[ { "cls_id": "homologset.agr.HGNC:31351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5F297-1", "uniprot_id": "S35G3_MOUSE", "id": "Q5F297-1", "name": "Solute carrier family 35 member G3", "aln": "MAASHPYFNLPDFTQPSPPSTPASLPSKHHHRCGPSNATKGLFVALLGGGLSAGFVGPFSRMAYQTSQLPSLELLIFRCLFHLPIALLLKFRGDPLLGPPDVRVRAFLHAILNVLSIGCAYSAVQVVPAGNAVTVRKGSSTVCSALLALCLESQGLSGYAWCGLFGSTLGLIIIVGPGLGTLQEGTTGLYTALGYVLAFLGGLALSLGLQIYRSLHFPSCLPTVAFLFGLVGLMVSVPGLFVLQTPVLPQDTLSWSCVVAVGLLALVSFVCVSYAVTKAHPALVCAVLHSEVVVALMLQYYVLYETVAPSDIMGAGVVLGSIAIITAQNLSCDKEGQTEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0K004-1", "uniprot_id": "S35G3_RAT", "id": "B0K004-1", "name": "Solute carrier family 35 member G3", "aln": "MAASHPYFNLPDFTQPSPPSTPSSLTSNHHNRCGPSNATKGLFVALLGGGLSAGFVGPFSRMAYQTSQLPSLELLIFRCLFHLPIALILKFRGDPLLGPPDVRVRAFLHAILNVLSIGCAYSAVQVVPAGNAVTVRKGSSTVCSALLALCLESQRLSGYAWCGLFGSTLGLIIIVGPGLGTLQEGTTGLYTALGYVLAFLGGLALSLGLQVYRSLHFPSCLPTVAFLFGLVGLIVSVPGLFVLQTPVLPQDTLSWSCMVAVGLLALVSFVCVSYAVTKAHPALVCAVLHSEVVVALMLQYYVLYETVAPSDIMGAGVVLGSIAIITAQNFSCDKEGQVEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7Q6-1", "uniprot_id": "S35G6_HUMAN", "id": "P0C7Q6-1", "name": "Solute carrier family 35 member G6", "aln": "MAGSHPYLNPPDSTHPSPPSAPPSLR--WHQCCQPSDATNGLLVALLGGGLPAGFVGPLSHMAYQASNLPSLELLICRCLFHLPIALLLKLRGDPLLGPPDIRGRAYFYALLNVLSIGCAYSAVQVVPAGNAATVRKGSSTVCSAVLTLCLESQGLSGYDWCGLLGSILGLIIIVGPGLWTLQEGITGVYTALGYGQAFVGGLALSLGLLVYRSLHFPSCLPTVAFLSGLVGLLGSVPGLFVLQPPVLPSDLPSWSCVGAVGILALVSFTCVSYAVTKAHPALVCAVLHSEVVVALILQYYMLHETVAPSDIVGAGVVLGSIAIITAWNLSCEREGKVEE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.****:* ** *:*****:*.** *: * **:**:**:********.******:*:****:*:******** **********:**:**********:* **:::*:*********************.************:*:****** **** ****:** *********** ***** **:****** **:********* :**************** *****: *********.****.* ****: ***:******.**************************:****:*:********:************** *:**::**:.**", "identical_positions": 273, "similar_positions": 43, "identity": "80.29%" }, { "cls_id": "homologset.agr.HGNC:31353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W4C2-1", "uniprot_id": "Q9W4C2_DROME", "id": "Q9W4C2-1", "name": "lysozyme", "aln": "---------------------------------------------------MRAAP---------FGSWYWLGLGLGLLLAIECGVVSAKRFLRCELARKLLDQ--HGFERSLLSNWICLLEHESDLDTGRITT-NANGSRNYGLFQINGR-FCQEG---RR--GGICNAKCEDFLDENLRESVTCAKRIQTSD-GFRHWAGWQRYCRNAQNLPNLKVICGI------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBX6-1", "uniprot_id": "A1ZBX6_DROME", "id": "A1ZBX6-1", "name": "lysozyme", "aln": "-------------------------------------------------MCLKARHPKTKRDLMNMKTFCLWIVPVLILLQLGIEQVESKKYQRCELTRVLVEN--YNFDKTFISNWICLVEHESYLDTTKVTK-KGNESKNYGLFQINSKDYCSEG---RK--GGQCNMKCEDFSNDDISDDIACARMIQERE-GFKYWKGWDRFCRNPQNLPNLRVACNLRSLSPVRSPRGFLTG---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBX7-1", "uniprot_id": "A1ZBX7_DROME", "id": "A1ZBX7-1", "name": "lysozyme", "aln": "---------------------------------------------------MASHLP--------KGGALFLVLNLLLLSQWET---ESKLLTRCQLAKELLR---HDFPRSYLSNWVCLVEAESGRSTSKSMQ-LPNQSVSYGLFQINSKNWCRKG---RR--GGICNIKCEEFLNDEISDDSRCAMQIFNRH-GFQAWPGWMSKCRG-RTLPDVSRC---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A2AE20-1", "uniprot_id": "LYZL5_MOUSE", "id": "A2AE20-1", "name": "Sperm acrosome-associated protein 5", "aln": "--------------------------------------------------------------------MKVCSIVVVILAVLLIAKLDAKIYERCELAKKLEEAGLDGFKGYTVGDWLCVAHYESGFDTSFVDH-NPDGSSEYGIFQLNSAWWCNNG---ITPTQNLCNIDCNDLLNRHILDDIICAKRVASSHKSMKAWDSWTQHCAG-HDLSEWLKGCSVRLKTDSSYNNW-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RCC1-1", "uniprot_id": "M0RCC1_RAT", "id": "M0RCC1-1", "name": "", "aln": "MLVFFFLLVFNRVCIQESGSAPSHVAHMFQNLSFRLVLIKPSILECYSLFLIITGSEARDHIEGFLAAMQFCSTVVVILATLLLATVDAKIYERCELARKLEKAGLNGFKGYTVGDWLCVAHYESGFDTSFVDH-NPDGSSEYGIFQLNSAWWCNNG---ITPTQNLCHMDCNDLLNRHILDDIMCAKRVVSSHKSMKAWDSWTRHCAG-HDLSEWLKGCDVPLKADSNYDDW-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QH8-1", "uniprot_id": "LYZL5_HUMAN", "id": "Q96QH8-1", "name": "Sperm acrosome-associated protein 5", "aln": "--------------------------------------------------------------------MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDH-NPDGSSEYGIFQLNSAWWCDNG---ITPTKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNGLSAWTSWRLHCSG-HDLSEWLKGCDMHVKIDPKIHP--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37161-1", "uniprot_id": "LYSX_DROME", "id": "P37161-1", "name": "Lysozyme X", "aln": "----------------------------------------------------------------------MRALLGICVLALVTPAVLGRTMDRCSLAREMAN---MGVSRDQLSKWACIAEHESSYRTGVVGPPNTDGSNDYGIFQINDMYWCQPS--SGKFSHNGCDVSCNALLTDDIKSSVRCALKVLGQQ-GWSAWSTW-HYCSG--YLPPIDDCFV-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83972-1", "uniprot_id": "LYSD_DROME", "id": "P83972-1", "name": "Lysozyme D", "aln": "----------------------------------------------------------------------MKAFIVLVALACAAPA-FGRTMDRCSLAREMSN---LGVPRDQLARWACIAEHESSYRTGVVGPENYNGSNDYGIFQINDYYWCAPP--SGRFSYNECGLSCNALLTDDITHSVRCAQKVLSQQ-GWSAWSTW-HYCSG--WLPSIDDCF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9D5-1", "uniprot_id": "A1Z9D5_DROME", "id": "A1Z9D5-1", "name": "lysozyme", "aln": "--------------------------------------------------------------MVRSSWSKVRVLPLLWFLFHGIPL-LAIRLQPCELAGQLYI---LDVPKSELPLWLCIAEFESRFNTHVVGQANADGSRDYGLFQISDRYWCAPPNRTEYYAFNDCNVNCTHLLSDDITMAVQCARLIQKQQ-GWTAWSVYPEFCNG--TLDAIDVCFQPGNATESMTSDELAEVKDC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.*: : . : * *: . ** * : * .**:**:.. :* . * .* : .: ** : . . * : * . * ", "identical_positions": 20, "similar_positions": 25, "identity": "8.33%" }, { "cls_id": "homologset.agr.HGNC:31357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGA2-1", "uniprot_id": "A0ABK0LGA2_RAT", "id": "A0ABK0LGA2-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "MGLLSGSTSVTLGMEYQLSPVRLVNAVLLGKRLRWIIITVLSTPCAWGLPHPHPARCARVRAAPLMPHAPSSPCRQTPGLRGPRDQLARPLCACAVGKRTGRSAGATTRMACAPGALGHRALWAVAWGLLLLVP-VLAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFADVFVALGPQHRAFGPYRGRAELQNDGPGDASLVLRNVTLQDYGRYECEVTNELEDDAGMVKLDLEGVVFPYHPRGGRYKMTFAEAQRACAEQDGILASAEQLHTAWRDGLDWCNAGWLRDGSVQYPVSQAREACG---GSGSPGAGGGTNGGVRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVALAGAVRACAARGATVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRTRCGGPRPGVRSLGFPDASRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGSRDPAAWTPLRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WM4-1", "uniprot_id": "HPLN4_MOUSE", "id": "Q80WM4-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "-------------------------------------------------------------------------------------------------------------MACAPGALGHRALWAVAWGLLLLVP-VLAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFADVFVALGPQHRAFGPYRGRAELQNDGPGDASLVLRNVTLQDYGRYECEVTNELEDDVGMVKLDLEGVVFPYHPRGGRYKMTFVEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVSHAREPCG---GTGSTGAGGGTNGGVRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVALAGAVRACAARGATVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRTRCGGPRPGVRSLGFPDASRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGSRDPAAWTPLRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UW8-1", "uniprot_id": "HPLN4_HUMAN", "id": "Q86UW8-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "-------------------------------------------------------------------------------------------------------------MVCARAALGPGALWAAAWGVLLLT--APAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFTDVFVALGPQHRAFGSYRGRAELQGDGPGDASLVLRNVTLQDYGRYECEVTNELEDDAGMVKLDLEGVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRARCGGRRPGVRSLGFPDATRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGARDPAAWTPLHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHT5-1", "uniprot_id": "A0A8M2BHT5_DANRE", "id": "A0A8M2BHT5-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "------------------------------------------------------------------------MRRWTSAVKRDSQKRDSCTTARLSLSSNNFIPSQHQTRHCMMMILFLEILTCTLLLLCPFVTSYPADLEKGRRRVVHVMEDDTGAVIVQTAPGKVVTHRGGTITLPCRYHHEPEDIDPNRIRIKWTKVSDAFQFEDVFVALGRQQKAFGSYQERVSLEQAGPGDASVIIHNITLEDYGRYECEVTNDMEDDTGFVNLDLEGVVFPYYPPSGRYKLNYHQAEEVCREQDAILASHPQLHKAWLEGLDWCNAGWLEDGSVQYPISHPRDQCG----------RKDSPPGVRNYGYRHKDDERYDAFCFTSNLNGRVYFLKRFKKVNYLEAVKACQRDGAFIAKVGQLYAAWKIQLLDRCEAGWVEDGSIRYPIVNPRARCGGPDPGVRNLGFPDKKFRLYGVYCFRKNTDIQSTQT------------PTETTSKMANSTRSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * .. : :. *. ::**::****:*.::*:*:******:**:******.******:*. . : :*:***** *.: * ******* *::***.*: *..*: ******::::*:**:***********::***.*:*:**********:* .****:.: :*:..* ***.**** *** ** :**********.*******:.:.*: ** .: *:*******: :************ ***:*** :: * *.:** ** :******:****:****** ***: *** ********:**** ****.***** . **:****:* :.: . : . * :. :", "identical_positions": 213, "similar_positions": 90, "identity": "41.52%" }, { "cls_id": "homologset.agr.HGNC:31367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R0J8-1", "uniprot_id": "GNTK_MOUSE", "id": "Q8R0J8-1", "name": "Gluconokinase", "aln": "-------MEAPGVLLVMGVSGSGKSTVGALLASKLG-----WKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQP--VVLACSALKKTYRDILIRGGSDAPLKSDDSAK-EPLAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPEN---FIQVSVDKSLPEITAAVMEALK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32PY9-1", "uniprot_id": "GNTK_RAT", "id": "Q32PY9-1", "name": "Gluconokinase", "aln": "-------METPGVLLVMGVSGSGKSTVGALLANKLG-----WKFYDADDYHSEENRIKMGKGVPLNDQDRIPWLCSLHDILLRDVASGQS--VVLACSALKKMYRDILNRGGSDVPPRSDESAKEEPLAGGKFLVVHLCGSFELIYGRLLQRRGHFMPPELLQSQFSILEPPSAPEN---FIHISVDKGLPEIAAAVLEALK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T6J7-1", "uniprot_id": "GNTK_HUMAN", "id": "Q5T6J7-1", "name": "Gluconokinase", "aln": "-------MAAPGALLVMGVSGSGKSTVGALLASELG-----WKFYDADDYHPEENRRKMGKGIPLNDQDRIPWLCNLHDILLRDVASGQR--VVLACSALKKTYRDILTQGKDGVALKCEESGKEAKQAEMQLLVVHLSGSFEVISGRLLKREGHFMPPELLQSQFETLEPPAAPEN---FIQISVDKNVSEIIATIMETLKMK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03786-1", "uniprot_id": "GNTK_YEAST", "id": "Q03786-1", "name": "Probable gluconokinase", "aln": "MTEKHKTMGKFKVIVLAGTAGTGKSTIAGELIHEFKDIYPDLKFIEGDDLHPPANVEKMTRGIPLNDDDRWDWLKKVAVESTKAAASTKEHLSIVACSSLKKKYRDLIR----------------HTCPESEFHFIFLYASKIEVLKRLKTRKGHFMKADMMESQFRDLELPDINDETDCDIVPLDFKTFYQIEKDVIQVVKSKVLNIE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .::: *.:*:****:.. * :: ** :.** *. * ** :*:**.*:** ** .: : .* : ::***:*** ***:: . :: .:.* .* : ** *.**** .::::*** ** * :: * * . :* :::.:* ", "identical_positions": 53, "similar_positions": 52, "identity": "25.36%" }, { "cls_id": "homologset.agr.HGNC:31369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N4H5-1", "uniprot_id": "TOM5_HUMAN", "id": "Q8N4H5-1", "name": "Mitochondrial import receptor subunit TOM5 homolog", "aln": "MFRIEGLAPKLDPEEMKRKMREDVISSIRNFLIYVALLRVTPFILKKLDSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AXP6-1", "uniprot_id": "TOM5_MOUSE", "id": "B1AXP6-1", "name": "Mitochondrial import receptor subunit TOM5 homolog", "aln": "MFRIEGLAPKLDPEEMKRKMREDVVSSIRNFLIYVALLRVTPYILKKLDSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6NZ76-1", "uniprot_id": "F6NZ76_DANRE", "id": "F6NZ76-1", "name": "", "aln": "MFKLEGLGPKMDPEEMKKKMREDVITSVRNFLIYVALLRVTPYVLKKLDSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::***.**:******:******::*:**************::*******", "identical_positions": 41, "similar_positions": 10, "identity": "80.39%" }, { "cls_id": "homologset.agr.HGNC:31371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LQ18-1", "uniprot_id": "A0ABK0LQ18_RAT", "id": "A0ABK0LQ18-1", "name": "", "aln": "MSARAVVPSSLAWGLLSFCFLCSGALGSQRPSRSLPPRPSQAKPGFGPTWMPPKGAEAALAFLYSGDVQQLSGANCSGKYEVRGAEGKAGVPPVLQRAAGTLAQAANFLNMLLQANDIREASVEEDVEWYQALVRSVAEGDPKAYRALLTFNPPPGASHLQLALQATRMGDETILQDLSGNKVQEENPEEDLDSPGLQKRVLTNDLRSLDSPKWPRGDGYVGDIQQVKLSPPFLECHEGRLRPGWLVTVSATFYGLKPDLTPEVRGQVQMDIDLQSVDINQCASGPGWYSNTHLCDLNSTQCVPLEGQGFVLGRYLCRCRPGFHGAGGSGGLEESATQTAGQFGSPQGSLGKLLGCQPCPEGCTSCLDATPCLVEEARALRTAVLACQACCMLAVFLSMLVAYRCRGSKRIRASGIVLLETILFGSLLLYFPVFILYFKPSVFRCVALRWVRLLGFAVVYGTIILKLYRVLQLFLSRTAQRGPHPSSGQLLQRLGQLLLLVLGFLVVWTAGVLEPGIQHTPLVTRGHTPTGRHFYLCHHDHWDYIMVVAEMLLLCWGSFLCYATRAVPSAFHEPRYMSIALHNELLLSTAFHTARFVLVPSLHPDWTLLLFFLHTHSTVTTTLALIFIPKFWKPGAPPREEILDEVYEDEPDLHRSGSYLNSSIASAWSERSLDPGDIRDELKKLYAQLEVRKTKEMAANNPHLPKKRGSSRQGLGRSFMRYLAEFPEALARQHSRDSGSLGLSSLPGSSRRRLLSSSLQGTEKAPALRKTRSTYEHHREHNTPPSESSLRRTLSKKASPTEGQVSVE-GPPALGFRSASAHNLTVGERLPRARPMSLQKSLSVVAGSREKALLVASQAYLEETYRQAKEREERKKAEAAMVSPVRRPSARRLEWPLRAPLSAPPSPAKSSSMESSHTPGRPHEEAGRRLPHPPIRHQVSTPILALSGACLGEPRMLSPTPTSTLAPVLLPALAPTPTPVLAPVSKPPQSPTLLTFICPWENAELPGKKENVVQEGPAGPERSSHTPASARTKIWRALSVAVEKKGTGESEALTEGGHVQGEADDTDEEKSKVFSKSHSLKTPLQQGSVRNLGLAIKALTRSRSAYKEKDGGEGTPETEKGKSTEVSTGAPPRSPRLGRPKAVSKQAALAPCEDEESLQNQQNAHTSRMLHVCQKEGSREQEDRNKRASQGPGERKIERTGKIALATLRQVFGEKNAEQAKESPVGYKEVPSLALQPLGSADHRVAEVCPWEVTESESGMGPQESVDKAKICSWEGTEGGGLEKKPSRQVLSRSWEEREKVPGESEPEGAGTITRKKPERLVRGQEAVCPWESPDSGGQSPQLVHQDSDRS-----QGRPVVVSKGEK------HPGALLPDAAKAELCLWEMRDVGEG--TSAQRVQELPEERHKSPKKATFWREQNLGGDLVSLCPWESTDFRGPSAVSLQAPGSS---GSFGSGITEICPWEAGELSNDKKAEVCPWELGDELAGTEALNQGTDRESLPGKEAASRKGCSVEVGGQTARAKSAVRQGQESVCPWEDETPEQSSPHPDNSSSKAGEKFLSNAGSQVLQVCPWEAIEPEERQATPSTVEICPWEVDGRT-ETRASEHAPKE-EVQKDEKKMPGRARIQ---AREETEGQIQKQEAICPWESTDCDSTSQR----TTENPQATLQKQGSMGDKAAEICPWDVEE--TAQKAKICPWDVDTGAGEERTVGAEASRISPNDASQTSADAGPSQVAGSALKKPERLSSEKEVVCPWDSMSPGTSSQQPDTLNTENVKDELQENVSP--RLLEVCPWETEEVPVSEKAKICAWELNEGTVGKGLEGETESEPAQPRRKNPEKAEFSFQEEGTSKGDTKLCQEEEAETACSWKP------PAQVSKASDLPSSSISQEAEGQSWEASDSASEKG----DLKTGSLPEYTSQGKV--AALKSQCSVDGGRASSELQPDCLRENMVAADSLSHPHSQCPDQPRASSQAPLSSEGGAAELCPWDASDPDLYKPDRDTKVELCSQRVTGRLTETETSRQDEEEKTQEEKERAPGKREHEGVAVQETPQTSNVGKQEAMCPRESQD---FGVQAATDASDGNKGSSE----------DVCPWEAEEVPSTEKAEICPWEAGPGAVGEEALDLGQDGES------QGAGGVERHLLRAA------EVVCPSEGSVSAGLYPQEDPVDTDRPKVSLHGASRQGK--AELCVWEVTDPEGNKIKGTMADICPWEEARAPPGESGLPALPVTQAD-VPAAPEKSVCLSVHTPLESSLPESKSVRPDVSKPPGTFPPEGVGEQE-PLEPEPGAKSSPK----EAEAPESLSLIEDQGQMASEAQAGDLSPPPDYPWDCE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PY61-1", "uniprot_id": "GP179_MOUSE", "id": "E9PY61-1", "name": "G protein-coupled receptor 179", "aln": "MGARAVVISSLAWGLLSCCFLCSGALGSQRPLRSLPPLPSQAKPRSEPMWMPPKGAEAALAFLYSGDVQRLSGANCSEKYEVRGAEGKAGVPPVLQRAAGTLAQAANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPKAYRALLTFNPAPGASHLQLALQATRMGDETVLQDLSGNKVQEETPGEDLDRPVLQKRVLTNDLRSLDSPKWPRGDGYVGDIQQVKLSPPFLECHEGQLRPGWLVTVSATFYGLKPDLTPEVRGQVQMDIDLQSVDINQCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYGASGSGGLEESATQAAGQFGSPQDSLGKLLRCQPCPEGCTSCLDATPCLVEEALALRTAVLACQACCMLAVFLSMLVAYRCRGSKRIRASGIVLLETILFGSLLLYFPVFILYFKPSVFRCVALRWVRLLGFAVVYGTIILKLYRVLQLFLSRTAQRVPHPSSGQLLRRLGQLLLLVLGFLVVWTAGALEPGTQHTALVTRGHTPTGRHFYLCHHDHWDYIMVVAEMLLLCWGSFLCYATRAVPSAFHEPRYMSIALHNELLLSTAFHTARFVLVPSLHPDWTLLLFFLHTHSTVTATLALIFIPKFWKPGAPPREEILDEVYEDELDLQRSGSYLNSSIASAWSERSLEPGDIRDELKKLYAQLEIRKTKEMAANNPHLPKKRGSSHQGLGRSFMRYLAEFPEALARQHSRDSGSLGLGSLPGSSRRRLLSSSLQETEKPPALRKTRSTYDHHREHNTLPFDSTLRRTLSKKASPTDGRESLADGPPALGFRSASAHNLTVGERLPRARPISLQKSLSVAAGSREKALLVASQAYLEETYRQAKEREERKKAEAAMVSPVRRPSTRRLEWPLRAPLSAPPSPGKSSSMDSSQTTARPHEEAGRRLPHPPIRHQVSTPVLALSGICLGEPRMLSPTPASTLAPILLPAPAPAPAPVLAPVSKPPQSPTLLTFICPWENAELPGKKENVVQEDPAGPERSGHSPASARTKIWRALSVAVEKRGTGESEALTEGGHVQGEADDTDEEKPKVFSKSHSLKTPLQQGSVRSLGLAIKALTRSRSTYKEKDGGEGTPETEKGKPTEVSTGAPLRSPRLGRPKAVSKQVALAPCEDEESLQNQQNAHTSRMLHVCQKEGSREQEDRNKRVAPGPGERKVERTGKITMTTLRQVFGEKNAEQAKESPAGYQEVPNPALQSLGSADHRVAEVCPWEVTEPESGMDPPESVNKAKVYSWERTEGGSLEKKPSRQVLSRSWEEREKVLAESETEGVGAIPRKKPERLVRSQEAVCPWESPDSGGLSPQLVHQESDRT-----GGRFVVVSKGDA------HPEALPSHAAKAELCLWEMSDVGEG--TSTQRVQELPEERQKSPKKATFWGERNLGGDLVSLCPWESTDFRGPSAVSLQAPGSS---GSLGSGIAEVCPWEAENIANDKKAEVCPWELGEELAGSDGLNPGADGKSLPGKETPSRKGCLAESGEQTVRAKPTVPQGQESVCPWEDEAPERSSPQPDKASSKAGEKLLSHGGSQVLQVCPWEAVKPEEKQATLSTAEICPWEVDGQP-ETRTSEHPSKG-EVHKDEEKMPGRARIK---AQEEAEGRIQKQEAICPWESMAPGSTPQR----DTEKAQASLQRQGSVAGRAAEIC----------------PWEVGTEVGEERTIGAEASEARPNDAGHASTDSGSRQVAASAPKKSERLGSEKEVVCPWDSLSPGDSSQQPDTPNTEKLKDELQEHGSS--RPIEVCPWEAEEVPTGEKAKICPWELNEGTVGKGLEREPGCEPERQRRQNLEEAGLPFQEEGTSKGDTKLCREQEGEAICPWKP------PAQVPKVSDLPLSTVGQGVEGQSLEASDRASEKGELRQDLKMGSLPEYITQ----------VVPVDGGGASSELQPISLQEGMVLAGSSSHPHIQCPDQPRVSSQPLVSTGDGTAEVCPWDAPDS-----DSDTKVEPCAQKVTGRVTETEMSRQDEKEKSQEEKERAPETRDHEGVAVQKMPQTSNFGKQEAVCPRESQD---FGVQAATDASDGSKGGSE----------KVCPWEVEEVPSIKEAEICPWEASPGAVGEGALDLGQDGES------QGEGRAERHLLKAA------ETVCPLEGTMSSGLFTQEDVVDTDLPKVGLHGASSPGKGLAELCVWEVTDPEGNKIKGTMADICPWEETRAQSDESGPLALPVTQAG-VPAAPEKSVCLSVHGPLESFLPESKSVRPDISKPPGSSRPEGVREQE-PLELETGAKSVPKPSPTETEAPESFTLTDDQGLMASEGEAGELSPPPDYPWDCE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PRD1-1", "uniprot_id": "GP179_HUMAN", "id": "Q6PRD1-1", "name": "Probable G protein-coupled receptor 179", "aln": "MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAALAYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSGNWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGRLRPGWLITLSATFYGLKPDLSPEVRGQVQMDVDLQSVDINQCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYGASPSGGLEESDFQTTGQFGFPEGRSGRLLQCLPCPEGCTSCMDATPCLVEEAAVLRAAVLACQACCMLAIFLSMLVSYRCRRNKRIWASGVVLLETVLFGFLLLYFPVFILYFKPSVFRCIALRWVRLLGFAIVYGTIILKLYRVLQLFLSRTAQRSALLSSGRLLRRLGLLLLPVLGFLAVWTVGALERGIQHAPLVIRGHTPSGRHFYLCHHDRWDYIMVVAELLLLCWGSFLCYATRAVLSAFHEPRYMGIALHNELLLSAAFHTARFVLVPSLHPDWTLLLFFFHTHSTVTTTLALIFIPKFWKLGAPPREEMVDEVCEDELDLQHSGSYLGSSIASAWSEHSLDPGDIRDELKKLYAQLEVHKTKEMAANNPHLPKKRGSSCQGLGRSFMRYLAEFPEALARQHSRDSGSPGHGSLPGSSRRRLLSSSLQEPEGTPALHKSRSTYDQRREQDPPLLDSLLRRKLAKKASRTESRESVE-GPPALGFRSASAHNLTVGERLPRARPASLQKSLSVAS-SREKALLMASQAYLEETYRQAKEREERKKAKAAMASLVRRPSARRLERPRGAPLSAPPSPAKSSSVDSSHTSGRLHEEARRRLPHPPIRHQVSTPILALSGG-LGEPRMLSPT--STLAPALLPALAPTPAPALAPVPVSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQ--PDSGNKAEICPWETSEG-APESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKT-RKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQ--ETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDLRQ----DPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPEL-KVSPKEAGSMGSRMAELCQWEITDPEGNKIKGTMADICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPLDHFFPESKIPCPKVSRPASTFTLEGVRELQGPSGLEPRTSLAPEPSLQEAES-QSSSLTEDSGQVAFEAQYEEFTPPTVYPWDWE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9ND25-1", "uniprot_id": "M9ND25_DROME", "id": "M9ND25-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELCIATKSKIETAQSSMPQSS-QCSSSSNCRNYQKKCHQNQTNTQVQSTQ-----------RSNCSSHSDRDHLTNQQKQQNQRTNS-----------------------------ATAASAAAATLSESTRCNIIISSSSSSSSSTKSSKNIREP------------------------------------------SSSSSTQLNTLYSLLVLLIVGLATATASPSPSP------------------------------------SHAPFGRE-----------------------------SRRDALLAYYKRAHLPQSSSSGISLGHKYH--------LLHDANGLDFDELTPTASSVSALSRAERFRLRKRSATP-----------------------TTPATAAGVTSLD------------------VATAAAAATDAAAKDAGSGKKPEEKCEPKVLETLPDEPFYDYT---------DIAEDAARQFIEFLSG---------------KFPNANTPIAIDEPTRAEVSRRANGIASYALNE-DDNLLAFAIAAPSIHTVVVKFRDNVTIPPDQ--------------VHNKAYLGSYWRELGAAWNSTDGTQEWGAPFRDCNLLTRRWLWPFRISFSEHRIKVVAAAFIAADEDVCNDG--------------------------------------LEEVFGRRHGCDRNTTFCLLTENKPAATRDVYTCLCRESYYLP---NSTLQGFRGDR--------------VELSEGYDNYSCIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVAIVLGACILCCIVLGVIVFRQRKCKAIASG----MWTVLETILLGIVLLYASVAVHFFPASTERCLLEPWLRELGFITCYGAIILKLYRHLVDFRTRKAHRWVLRDVD-------------LLKYLGTMVFAVICYMAAFTASSLDLLESAQLESLREADTNTCHPLKWELVTQTSEMLILCFGLHLSIASRN------------------------------------------------------------------------------------------------------------------------------------------------ANTQFRERQFLVTALTLEFLVSSSFYFLRFVYLPEMSPS--------------------------AILLALFIRSQLTNSFALG---------------------------LIFVPKLWYQHKQVRSLAYDLSIRLPVDAFKGTSHDAGQRLGGGYAGLCLGDP--------DIGELTISEMSPEDIRAELKRLYTQLEIMKNKTLRQDNPHISKRRGGR------------------------------------KAGHRRFSLQKKG------------------------------------------------------------SKDKALSAKHRSNKHHQDIEITEAEPSRTPEDS----------------------------VCSAEGPTDTYAEISGVSHSMLSHSMVSHSVVSHSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DY43-1", "uniprot_id": "A8DY43_DROME", "id": "A8DY43-1", "name": "G-protein coupled receptors family 3 profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------MRMWVRMPQAVQLLFAMGLWAMQGHAQLDSEPEAVGAEGAAGPGSPAPRNRIKAEADALMTGDSFNIRHG-------------------RSRSHFLHGSTNSSSSSGIGSGGGTTRLTLIPPTQLPGVGGTSP-----------------APVTHKIRKLHKKKINESIRKSVDKSLGLRHTPKNHRSLAEAEHLQGR------------PASEDAEDTALSEVMQLADEIELESS---------------------------FVTAAPTGDPDIGVKQARQFVRDEANYQEDDDDTIDDDEELDEEEEE------------------------------------APMSTTIKPKIASTRLLPVNGTWQRMGTISRDS-----------------------------------PPESDYDSNALDNAQED---------------------EEEEEGQPFGKLLPLNESLATTEWMDDGAQREPEAEARSQAASMEVKQISFDSDGDSDSEAGLDTSEVTMDDGYPPDAQVDDKTKQLVIG-DVEEDSGDNMESNQFTADVINARDSKIDLVSKFLQYIEQQHLMGSNCVAGTSLNLGEGVVDR-YAQDRFRVEAEVAVNRANMLTRIFKTTGRSVQEDVNLLHASVLSMVEFDDDIFAAGNCFDWNEHPAQPGLFCPFAYRLPPPNLGAVFAKDLAMEYHYLGNTSEWFFLARKNAEKVIARNEQYLKSFHLYSNRTEERIEDDTLAVKYEDGRWSKPYYDCGGGNIWMLTYTVPFFGYENGTYHFKGTSGIDIDLRRVDIDQCPQRHTPGTKR--------------------------------------PLNIFAGTDKCKQRTTMCEAIMG-LGFRRGSYKCLCRKGFYFPDIVSQHKFFN----------GSLLEEEYEKLMLGKNSTYNSNSEYECLPCAEG--CDSCEDSSPCIAALNWPMRTSILALACIVIGLLPPAAWFTFRYQQVKVVRAASPALLR--VIALGAFFIYCTNIVMYPNPNLYTCTARIWLREIGFSLTYGALMLKTWRISVIFRVRSAKAVKITDAA-------------LLKRLGIICGAIGTCLLVRTLVSPPDVVVG--RTADDLKAFLCKTDWWDYTFTSMEVLFLAWGVRLCIMVRK------------------------------------------------------------------------------------------------------------------------------------------------APSEFNESRFIS-MAIYNEFLLTCFLNVSMLFLQSPANP-------------------------DLLYIIFFCHTQLTVTLLLA---------------------------LIFGSKVYIVLRSGKSHQENIGMGTKASGAKFNFRPQVRTFANPSSVTTSTVPVAAETKLSDQEALEEIRQLSMQLQRIQEMAPPKGVAVMTISSLLDGLKTPGGLMVVAAAAGATAQG-------------------------HSAANRQSALPLLALN---------------------------------------------------VEMQKYSQQNNNSNGGRGSGRTSIPTMVLETPPSSTPPSAAYEERAVNTELSGDDFREQLLR-----RTADGHIICSRCLDASKEHYYCCPPRSACDHLGSPKEEGSLSFANIKLECMCSQSEDLDQDVGQRQRRPTVRTAATN------------TPPTSCKRAPRNLLEAELSISYQICDNCRSKYKLTGRRRSG--------------------SYSQAQENPQLGQQPAGQLPIQSRSTELLDRTTAAEVETEVEARTKAAHSTDDIVLYS------------SAPEELAAQLAEPVAAPSLGNVSSNSNNSTSGSGGTTRPKRPDKLVLDLNDRSKYTKEVSV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKA4-3", "uniprot_id": "Y1760_DROME", "id": "Q9VKA4-3", "name": "Probable G protein-coupled receptor CG31760", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKCWHNVVRRRRKKPTAAAAAKGS------------KGSHGGVASPRDEDAICQRQQQVDT-----------------------------YTWLTTQAVPLLWLHLLLLVAFAKHAAAATTIATN------------------------------------------------PEATTTTVSNYTVTTTALSSSTTTTSSGSAPA-------------------------------------------------------------------------LSSAADKFAGNWANLEDSFRNIVRIGDGNTVTRTSIEQSLVTIHDIATENLGTLCISTLYRPLQVPINSERYESSRQKTDLAASILQEVGIIRHGGLSDALAKGLLTDDFITG-----------------ARILALNLTNGAVQSYVWWVKGTAAEIQRYDEDGLQIGKKPAGSYPWFDDETSSPTLRSPKFAPSPPNN--------------YYKGWWTYPYFSCSQSRWLVSYSIAIPPIGRHG----LRGFISIDIDVSTLRVNQCEAEP------------------------YPFGSRRQKMQQLQTHNRLGARRSLFLGSRMGAIDESTINDLQAFHSSHKCHRTSMVCDYRQPSAET-----------------------------------------------PTVTGGKLLTTLTGSSSWTRGSYQCLCRGGFYSLRHPDGFN-------------GTIMEIAWQEQQDNISNYYS--EVFKCLPCAPG--CDTCTGPEPCLANYHWPFRISLLTISIGCACGTFVLAGYLFRHRRVKVFKVASPIFLM--ITLIGCAIMYLEMVAIFPYLDTTWCIATKWTRHMGFCITYTSLLMKTWRVSLTYRVKSAHKIKLNDQQ-------------LLQWMVPILLVMLIYLGTWTISATP--TAEVILDQSQLKFKQCSYNWWDHSLAIGEVFFLAWGIRVCYNVRN------------------------------------------------------------------------------------------------------------------------------------------------AESLYNEARLISYAIYNIALVNIAMVVFHVMLFPNAGPD--------------------------YKYMLGFVRTQLSTTTTIA---------------------------LVFGPKILRVFKGQGDKWDQKAKVRSITAS--FSLNGVGLVPEESPDLYQENEELKEQVQKLAHQIEFMKTVHMQMNNRHLKPKPGGYFTITSTSFQAPYSKNTVSTAQT-----------------------------------QTGKDENSTPTKLKS----------------------------------------------------------PKGKVXRGQRSVKDCSIEIDGGQGRTTLVEDAIEFNFHLADTEKGLIVQEDERPG-------SDEEEAALIAQFRRLFAPILDDSLNLYYQLNDLDDTEHVRIHQTVAQMNDLTSSEEETMVTQVN------------------------------------------------------------------------------------SPSPPPVGVELLLPISSDSSTASSSLYAIHTPSPAHPSGVLLMPQN-----------------------------LESPLLSGSDAITITEQVELHNPPHHLQLLEDENNTSCSLSSNLTDSKTLDGRTPIVV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . : : . * . : * : : : . :. : : . . : . : : : . . * : : . : . : . : * . . . .. . : .: : : . . .: : : : :. . : : : : . . . . *: : : : : * . : : : . :: : : . . . . :: . : . . . . : . . : ", "identical_positions": 6, "similar_positions": 94, "identity": "0.25%" }, { "cls_id": "homologset.agr.HGNC:31394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JN27-1", "uniprot_id": "TF2H2_RAT", "id": "A0JN27-1", "name": "General transcription factor IIH subunit 2", "aln": "-----------------------------------MDEEPERTK------------------------------RWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKTAKIRVSVIGLSAEVRVCTVLARET----GGTYHVILDETHYKELLARHVSPPPASSGSE-CSLIRMGFPQHTIASLSDQDAKPSFSMAHLDNNSTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYKGE--------RFCYGCQGEL-----------KDQHVYVCTVCRNVFCVDCDVFVHDSLHCCPGC-------------------VHKIPTQS------GV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIB4-1", "uniprot_id": "TF2H2_MOUSE", "id": "Q9JIB4-1", "name": "General transcription factor IIH subunit 2", "aln": "-----------------------------------MDEEPERTK------------------------------RWEGGYERTWEILKEDETGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKTAKIRVSVIGLSAEVRVCTVLARET----GGTYHVILDETHYKELLAHHVSPPPASSSSE-CSLIRMGFPQHTIASLSDQDAKPSFSMAHLDNNSTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEISLEEYKGE--------RFCYGCQGEL-----------KDQHVYVCTVCQNVFCVDCDVFVHDSLHCCPGC-------------------IHKIPTPS------GI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13888-1", "uniprot_id": "TF2H2_HUMAN", "id": "Q13888-1", "name": "General transcription factor IIH subunit 2", "aln": "-----------------------------------MDEEPERTK------------------------------RWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARET----GGTYHVILDESHYKELLTHHVSPPPASSSSE-CSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGN-TEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGE--------RFCYGCQGEL-----------KDQHVYVCAVCQNVFCVDCDVFVHDSLHCCPGC-------------------IHKIPAPS------GV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNP8-1", "uniprot_id": "Q9VNP8_DROME", "id": "Q9VNP8-1", "name": "General transcription factor IIH subunit", "aln": "----------------------------------MADDEQEDQKE----------------------------YRWETGYEKTWEAIKDDEDGMLDGAIAEIIQKAKRQRQAQKSKQNRLGMMRHMFVVLDCSESMSVPDLKPTRLRCTVKLLELFIEEFFDQNPISQLGLIALKAKRAEKVTELTGTSRVHLKALESLANVSLTSEPSLQNGLDLALKSLKVVPSHASREIVIIMGSLTTCDPVDINLTIDELKKEGIRCSVISLSAEIHVARYLTQQT----MGTFGAVLDDAHFRDQLMSQVDPPPAAKTQH-NSLIRMGFP-HTKNEVEGKDAPLSMCMCHIENLEEPSELTTTGHHCPQCNSKYCELPVECQSCGLTLVSAPHLARSYHHLFPVPNFEELPFEAMPASSSDLTSDVRECYGCAKALGQGV----DKVADKVVFRCGFCKQFFCVDCDIFIHDTLHACVGCNTIPGVDGLVYQQSSKSDQVDAHPGPSKQRGQCGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04673-1", "uniprot_id": "SSL1_YEAST", "id": "Q04673-1", "name": "General transcription and DNA repair factor IIH subunit SSL1", "aln": "MAPVVISESEEDEDRVAITRRTKRQVHFDGEGDDRVDQQQQQHSSSHRDRDKHVQRKKKKRLSNRNLQGSNGGYAWEDEIKRSWDLVKVDDEGDMASLVASIVEARKKRTAKKNITPYQRGIIRSLILTLDCSEAMLEKDLRPNRHAMIIQYAIDFVHEFFDQNPISQMGIIIMRNGLAQLVSQVSGNPQDHIDALKSIRKQEPKGNPSLQNALEMARGLLLPVPAHCTREVLIVFGSLSTTDPGDIHQTIDSLVSEKIRVKVLGLSAQVAICKELCKATNYGDESFYKILLDETHLKELFNEAVTPLPVNKINKGFTLVKMGFPTRIFEDT------PTFCSCH-------SKLVYGGYFCPNCHSKVCSLPTVCPCCDLMLILSTHLARSYHHLMPLKTFAEVPTTEKFRS--------EDCFSCQSRFPILKNHKNGKLLTSSRYRCEDCKQEFCVDCDVFIHEILHNCPGC--------------------ESKPVIT--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : . ** :::*: :* *: * : . : .*: *:: :: : *::* : :.:* *.:* **:*.* :: *:.*:********:*:* : *: :::::*..: *: :*:. . .:*** *.*.:* * :*.* :**::*::.**:* ** :* *. * ** .*:.***:: :. * : * . : :**::* :: : * * *. . .. :*::**** : . ::. .* . *. *:.**:*.:* *.**. * *.* *: :.*********:*: * *:. . . *:.* : . : * *:: ******:*:*: ** * ** . * : ", "identical_positions": 117, "similar_positions": 128, "identity": "22.94%" }, { "cls_id": "homologset.agr.HGNC:31397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14B24-1", "uniprot_id": "PRS57_MOUSE", "id": "Q14B24-1", "name": "Serine protease 57", "aln": "MPSSTAMVPGTRGGWHCLVLTTAAALTQLMWLP-GCCGSYIVGGHEVTPHSRPYMASVSFEGHHYCGGFLIHTHWVVSAAHCFSDRDPSMGLVVLGAHALLAPEPTQQTFSIAAAVSHPDFQPATQANDICLLRLNGSAVLGPAVRLLRLPRRNAKPPAAGTRCHVSGWGFVSDFEEPPPGLMEVEVRILDLSVCNSSWQGQLNPAMLCTHSGDRRRRGFCSADSGGPLVCGRRAHGLVSFSGLWCGDPKTPDVYTQVSAFVTWIWDVVR-ASSSPGSTGRSVRAV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IE59-1", "uniprot_id": "PRS57_RAT", "id": "Q6IE59-1", "name": "Serine protease 57", "aln": "------MVPGTGGGRDCLTLVVATALTQLLWLP-GCCGSHIVGGHEVKPHARPYMASVNFEGHHHCGGFLFHAHWVLSAAHCFSDRDPSTGLVVLGAHALLTPEPTQQVFGIAAVVSHPDFEPTTQANDICLLRLNGSAVLGPAVRLLRLPRRGAKPPVAGTRCRVSGWGSVSDFEEPPPGLMEVEVRILDLSVCNSSWQGQLSPAMLCTHSGDRRRRGFCSADSGGPLVCGNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVSWIWDVVR-ASPTPGSMGCSLRAV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWY2-1", "uniprot_id": "PRS57_HUMAN", "id": "Q6UWY2-1", "name": "Serine protease 57", "aln": "------MGLGLRG-WGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLPGTTRPPGEAA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * *..*:** : * *. *: *:*****.**:******* * *:*:*****::::**:*******.** ********.* :.*****.*.* * .:***:.* *:******************* *** * * *:**.*****:*:*** ****** ******.:**:** .******:*:*. :****:*** :*************** .*****************************:******* :*. **. : *. ", "identical_positions": 188, "similar_positions": 48, "identity": "64.83%" }, { "cls_id": "homologset.agr.HGNC:31399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31662-1", "uniprot_id": "S6A17_RAT", "id": "P31662-1", "name": "Sodium-dependent neutral amino acid transporter SLC6A17", "aln": "MPKNSKVTQREHSNEHVTESVA--DLLALEEPV------------------------------------------------------DYKQS--VLNVAGETGGKQKVAEEELDAED-RPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVI-RNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYNVIMTVKEKQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDT---FKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSP---MPTHRSYLGPGSTS---PLESSSHPN--GRYGSGYLLASTP-ESEL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJI1-1", "uniprot_id": "S6A17_MOUSE", "id": "Q8BJI1-1", "name": "Sodium-dependent neutral amino acid transporter SLC6A17", "aln": "MPKNSKVTQREHSNEHVTESVA--DLLALEEPV------------------------------------------------------DYKQS--VLNVAGETGGKQKVAEEELDTED-RPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVI-RNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYSVIMTVKEKQFPALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDT---FKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFQPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSP---MPTHRSYLGPGSTS---PLDNSNNPN--GRYGSGYLLASTP-ESEL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1V8-1", "uniprot_id": "S6A17_HUMAN", "id": "Q9H1V8-1", "name": "Sodium-dependent neutral amino acid transporter SLC6A17", "aln": "MPKNSKVTQREHSSEHVTESVA--DLLALEEPV------------------------------------------------------DYKQS--VLNVAGEAGGKQKAVEEELDAED-RPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVV-RNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSRDLIPPHVNFSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDT---FKVPKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVVATLPIPVVFVLRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSP---MPTHRSYLGPGSTS---PLETSGNPN--GRYGSGYLLASTP-ESEL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WEE1-1", "uniprot_id": "X1WEE1_DANRE", "id": "X1WEE1-1", "name": "Transporter", "aln": "MPKSSKVTQREHSNEPVTESVA--DLLALEAPM------------------------------------------------------DYKSSQMSMNMTGGSAPPIGKPDISPDLEDGRPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYFILLILIGIPLFFLELAVGQRIRRGSIGVWNYVCPRLGGIGASSLMVCGFVGLYYNVIIGWSIFYFFQSFQYPLPWSDCPIR-KNGSQAIVEPECEKSSATTYFWYRETLNITSTIADSGGLNWRMTLSLLAAWIIVCLAVIKGIQSSGKVMYFSSLFPYVVLFCFLVRGLFLKGAVDGIAHMFTPKLEIMLEPQVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSVINFLTSILATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSHDLIPPHVNFSHLTTSDYAEMYGVIKIVKEDSFAQLGLEQCLLEDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFFMLINLGLGSMIGTMTGITTPILDT---FKIRKEYLTVGCCIVAFLCGLLFVQRSGNYFVTMFDDYSAGLPLTIVVILENVSVAWIYGTKRFMQDLEDMLGFRPYSVYFYLWKYVSPVCLIILISASVVEMAISPLGYNAWVQDLAMERFQSYPPWAIVMCFALIIVAMLPLPLVFIARHFNWLPDGSNKLSVSYRKS-LAKEASTLE--DETRFILGKNPSEAPSP---MPSHRAYLGPGSTS---PVELITNSTSISGYGSGYQTNPAPPKSES-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7V4-1", "uniprot_id": "A0A0B4K7V4_DROME", "id": "A0A0B4K7V4-1", "name": "Transporter", "aln": "MAATKIIDAPRNGHEMAP--------LNTRARG------------------------------------------------------DGTHG-VTIVLTAPQRNSVQSVDIPGNEPE-RAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLN-GTG---FELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILV---KNKLLG--------------LNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFLMRSFQCLKVDLDIHQGSIRRNETTASTKEMIDNDDDDDEDDENDFSGPALGGHVKTQSDFSDDDEEDKPMTMRMMMMRPTTTTKTSNVLNVPTSRKNNYKKEAYDV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z122-1", "uniprot_id": "B7Z122_DROME", "id": "B7Z122-1", "name": "Transporter", "aln": "MANTAQLLRRQSSRDIILKSQKSIDQLELRELRGRLVSKEHGVSHHHHTSLHHQPLYGATNQGFMSDAFDESSELEQDPPPFGSEASTSKAKAELVAIATASADQQDIVEGEKEGEE-RESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWADCPTRLYKNFTYDHEPECVASSPTQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEE---------RNGLVAQN-------------------------------KTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNLPKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCWKYLSPCAMVTILLASFYQLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIVAVLRLCGIKVVEDS--DPAWFPEAELREVHGIVPHEPTELER---------------SIFCFNMDGTEG---------------MCCPKYGLPEKSLEEEE-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . : . . : * . . : :: : : : * :*..*: ::*: :*::*****:******.*:*****:*:*::::* : ***:* :**.:***:* *::*** : * ***** ** :* :*.****.** * .:*:::**. ****:.** .. ** ** * ::*** :*: : :: . .::: :.:.*: :* :* : :::** ****::*::::***:** *:.**: *:** *: *::**: : :*:* ** :*.**:*:::**.**.:***.*** .*** *. ***. * *:: * :*:*:::****. ::*. . .. ::. * * * ** ::..******* **:*: .:*.: :*:*:** **:.**:.* :* : *: .:.* .: *: .. *. . .: * :*.* . ::*.::. : * ::.::* ::: :*** .:* ::: * * :* : : *:::.* : : :*. : * ** . . . :* * : : : :* . * :*:* : * . . : . : : : : . . . . :.: ", "identical_positions": 192, "similar_positions": 222, "identity": "23.82%" }, { "cls_id": "homologset.agr.HGNC:31401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K938-1", "uniprot_id": "A0A0G2K938_RAT", "id": "A0A0G2K938-1", "name": "Solute carrier family 9 member C1", "aln": "TGMEEVFENLTTTHNVKLSNAWLDLLKSVFLSTPQDLPEIILILSLICTIGAFLNMHLKDFPIPLPVILFLIGCCFEILSFASTQIQLYADAIQWMDPDMFFGIFTPVIIFNVAFDMDIYMLQKLFWQILLITIPGFMINYTLILWYLQSVNKLSLKTIPWLLFSAVLISSDPMLTSASIRDLGLSRSLTNLINGESLLTSVISLIIYSAVVQISFKSKH-MNHTLAHKVMSTAWSYLVESFITGILITKAIQLWMATIFGDDVNHITLIFSVLYLIFYVCELIGMSGIFTLATIGLFLNSTSFKPGVEA-FLLEFWNCLSFIGFLMVFTFIGLLIPAHTYLYISFSDVYYSLNIYFTLIVLRLLVFLLMSPILSRLGHGFSWRWAFIMVWSEMKGTPNINMALLLAYSDVSLGSERERSQILFHGVSVCVITLIVNRFILPMAVIKLGLRDVTSTKYKSVYYTFQHFQELTKSTAMALKFDKDLANADWNMVDKAIILQNPYALNQEETTEHQKVKCPDCNKEIDETLNIEAMELANRRLLSAQIASYQRQYRNEILSQSAMQVLVGAAGSFGEKKGEYMSPENIKNYSESKKLLSFLRKLLLNWVYNTKKDKGVPSRYMFLHACHSIVFTNEFEYTGYIAVLMNTYPMIICWISRLKDIYQYEIKCANYYFLTFYILEALLKVAAMRKEFFSHTWLLFELGITLVGILDIILIETDSISYKFDLTETVVFMNVVRLLRILRILKLITPKLLQVIDKRMSQQISFRYAILKGYVQGEMDVLNIIDQIASSKQAKQILLKRVIRNMDHAMKELGYLEYDHPEIAVTMKTKEEVNVMLNMAREIVKAFRSKGIIHKVEGAEINKLIMAKKKQVLELQSVIQPLNVEEAPYYIPWLSEDPEAISFIQEKAKVVTFDCGNNIFEEGDEPEGIYVIISGMVKLKRSKPHLEMDRVSSESEVAQTRSYTLPHTEYLLSGEIIGELNCLTKERMQYSATCKTVVETYFIPISHLYEGFEKKYPNMKYKMWQKIGLAITAQKIRENLSFEDWNYKMQLKLCNVFVRDIPKTTKTDIYDETVTHVVLIHGSAEDCQLRKIYKAPFLIPVTCHQIQGLEEFTKVMIIQTSVAVRKFRWNVKKYNPPRRISMKPDS-TESLETLNESSEDDEDKKENEENEEYLEDI------------------IDISSVSKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UJY2-1", "uniprot_id": "SL9C1_MOUSE", "id": "Q6UJY2-1", "name": "Solute carrier family 9 member C1", "aln": "MEMEEISENLTASHSIKLTNMWLELLKSVFLSTPQDLPEIILILSLICTVGAFLNMHLKDFPIPLPVILFLIGCCFEILSFASTQIQIYADAIQWMDPDIFFGIFTPVIIFNVAFDMDIYMLQKLFWQILVITIPGFLINYTLILWYLQSVNKLSLKTVPWLLFSAVLISSDPMLTSASIRDLGLSRSLTNLINGESLLTSVLSLVIYSGVVHIRFKSKS-VNHTLAHKVMSTAWSYIVESFITGIVFTKVIQLWMATIFGDDVNHITLIFSVLYLIFYVCELVGMSGIFTLATIGLFLNSTSFKPGVEA-FLLEFWNCLSFIGFLMVFTFIGLLIPAHTYLHISFSDVYYSLNIYFTLIVLRLLVFLLMSPILSRLGHGFSWRWAFIMVWSEMKGTPNINMALLLAYSDISLGSERERSQILFHGVSVCVITLIVNRFILPMAVTKLGLRDVTSTKYKSVYYTFQHFQELTKSTAMALKFDKDLANADWNMVDNAIILQNPYAMNQEEITEHQKVKCPDCNKEIDETLNIEAMELTNRRLLSAQIASYQRQYRNEVLSQSAVQVLVGAAGSFGEKKGEYMSPENIKNFSESKKLLSFLRKLLLNWVYNTKKDKGVPSRYMFLHACHRIVFTNEFEYTGYLVVLMSTYPMIICWISRLKDIYDNEIKCANYYFLAFYILEALLKVAAMRKEFFSHTWLLFELGITLVGVLDIILIETDSISYNFDLTETVVFMNVIRLLRILRILKLVTPKLLQIIDKRMSQQISFRYSILKGYVQGEMDVLNIIDQIASSKQTKQILLKRVMRNMEHAMKELGYLEYDHPEIAVTMKTKEEINVMLNMAREIVKAFRSKGIIHKVEGTEINKLIMAKKIQVLDLQSVIQPFNVEEAPCNIPWLSEDPEAITFIQEKAKVVTFDCGNNIFEEGDEPEGIYVIISGMVKLKRSKPHLEMERVSAES---EIKIHPLPHTEYLLSGEIIGELNCLTKERMQYSATCKTVVETYFIPISHLYEGFEKRCPNMKHKMWQKIGLAITAQKIREHLSFEDWNYKLQLKLCNAFIRDIPKSMKTDIYDETVTHVVLIHGSAEDCQLRKIYKAPFLIPVTCHQIQGMEDFTKVMIIQTSIAVRKFRWNVRKYIPPRRISMKPDSERESFETLDETSEEDNGKKENQENEELIEEN------------------INI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0N8-1", "uniprot_id": "SL9C1_HUMAN", "id": "Q4G0N8-1", "name": "Solute carrier family 9 member C1", "aln": "---------------------MAGIFKEFFFST-EDLPEVILTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTVFGDDVNHISLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEETLLLEFWTFLSRIAFLMVFTFFGLLIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSRVGHEFSWRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITLVVNRFILPVAVTILGLRDATSTKYKSVCCTFQHFQELTKSAASALKFDKDLANADWNMIEKAITLENPYMLNEEETTEHQKVKCPHCNKEIDEIFNTEAMELANRRLLSAQIASYQRQYRNEILSQSAVQVLVGAAESFGEKKGKCMSLDTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGPSKYFFFRICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKLIAPKLLQIIDKRMSHQKTFWYGILKGYVQGEADIMTIIDQITSSKQIKQMLLKQVIRNMEHAIKELGYLEYDHPEIAVTVKTKEEINVMLNMATEILKAFGLKGIISKTEGAGINKLIMAKKKEVLDSQSIIRPLTVEEVLYHIPWLDKNKDYINFIQEKAKVVTFDCGNDIFEEGDEPKGIYIIISGMVKLEKSKPGLGIDQMVESK----EKDFPIIDTDYMLSGEIIGEINCLTNEPMKYSATCKTVVETCFIPKTHLYDAFEQCSPLIKQKMWLKLGLAITARKIREHLSYEDWNYNMQLKLSNIYVVDIPMSTKTDIYDENLIYVILIHGAVEDCLLRKTYRAPFLIPITCHQIQSIEDFTKVVIIQTPINMKTFRRNIRKFVPKHKSYLTPGL-IGSVGTLEEGIQEERNVKEDGAHSAATARSPQPCSLLGTKFNCKESPRINLRKVRKE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*..*:** :****:** ****.::***** **:*****:******:**.**:***:*:*:* **:*****.**:** *****::*..***** ***********:*:****::** *:**:* ***:* **. ******:*:*******:*:********** .*******:***:**: ::.::.: : : *****.:::. **:: **: **: :* **:**:*:********:****:******:***:********* :**:*******..:* :*****. ** *.*******:**********:*.* *:*******:******:*.:**:**:***:** ***** **** ***** *************: :**::*:******** **:***:*******:** *****.******** ***********:* ***************:::** *:*** :*:** *********.******* :* *****:*******************:*****:******* *******: ** :.***:***:* ::* ***********:*:* **:*:*:: ** ****:***:.**:.:**. :*:**.***:*: **. *:* :** **::********:*****:****:* :***.***:*:*.:**** *:*.* *: **.:**::*::::*****:**::*****:******:* :* *.********* *::.*****:**** **:***:*:***:**:****************:*****:******* **:*** **** *.**: ********* :**: **:*:*:.***. ****.:: : *.***************:********:***:********::*** * :::: .. : ..: .*:*:********:****:* *:*********** *** :***:.**: * :* *** *:******:****:**:*****::****.* :: *** : *******.: :*:****:.*** *** *:******:******.:*:****:****.: ::.** *::*: * :: :.*. *. **:* :::.. **: :. *:: ", "identical_positions": 763, "similar_positions": 263, "identity": "63.37%" }, { "cls_id": "homologset.agr.HGNC:31406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LE87-1", "uniprot_id": "A0ABK0LE87_RAT", "id": "A0ABK0LE87-1", "name": "WD repeat-containing protein 37", "aln": "MPTESG----SCSTARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLE-LFGQIEREFENLYIENLELRREIDS-LNERLAGEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYIGHRDGIWDVSVARTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDLDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSED-HPICNLFTCGFDRQAIGWNINIPALLQEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBE3-1", "uniprot_id": "WDR37_MOUSE", "id": "Q8CBE3-1", "name": "WD repeat-containing protein 37", "aln": "MPTESG----SCSTARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLE-LFGQIEREFENLYIENLELRREIDT-LNERLAGEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSED-HPICNLFTCGFDRQAIGWNINIPALLQEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2I8-1", "uniprot_id": "WDR37_HUMAN", "id": "Q9Y2I8-1", "name": "WD repeat-containing protein 37", "aln": "MPTESA----SCSTARQTKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLE-LFGQIEREFENLYIENLELRREIDT-LNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYAVQLPTPQPVADTS--ISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSED-HPVCNLFTCGFDRQAIGWNINIPALLQEK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEE4-1", "uniprot_id": "E7FEE4_DANRE", "id": "E7FEE4-1", "name": "WD repeat-containing protein 37", "aln": "MPVESG----NSAAARQVKQKRKSHSLSIRRTNSTEQDRTGMQRDMLEGQDSKLPMALRSNLLD-LFGQIEREFENLYIENLELRREIES-LNERLSGEGQTVEGGDLSKGALKTKASHSTSQLSQKLKTTYKASTSKIVSSFKATTSRAVCQLVKEYVGHRDGIWDLAVTRVQPLVLGTASADHCSMLWSIETGKCLLKYAGHAGSVNSIKFHPTEQMALTASGDQTAHIWRYMVQLPLPQPPADIS--ASLDDDVDFSDKDEADGDADGPNECPTIRVATTTLKSHQGVVIAADWLVGGKQVVTASWDRAANLYDVETSELVHTLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAVNRISVSANQRIIALPHDNRQVRLFDMNGVRLARLPRSNRQGHRRMVCCSAWNEE-NQACNLFTCGFDRQAIGWNINIPALLQEK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE73-1", "uniprot_id": "Q9VE73_DROME", "id": "Q9VE73-1", "name": "WD repeat-containing protein 37", "aln": "MKASKTRAVRLTSLTEDVAAVPEDAPFRARLHVLFAQIEREFEQLYLENQALQEKLDIATTTKESLIPPDARSAAGGSMSTQASSAALATPATQTDEVAGSFLAAASSTHKSLKAKLSSATGGSKAKASNKIKAQTSRIVSSFKAPT--VVSTVVREFGGHKDGIWQVAAKAGQP-IIGTASADHTACIWGVESARCLLQYQGHAGSVNSIKFHQQRDLVLTGSGDGTAHIWQAAVNWEVPKK--------GHSSEEELDDSDEQVEDRDRVDTLRTPLCEFTGPGGHLSVVVAADWLSSMDQIITGSWDRTAILWDVETGLPLQPLTGHDHELTHVSAHPTQRLVVTASRDTTFRLWDFR-EAIPAVSVFQGHTETVTSSVFARDDKVVSGSDDRTIKVWELRNMRSALATIRTDSSVNRLAVSTGG-IIAIPHDNRQIRLFDLNGQRVARLPRTSRQGHRRMVSSVAWAEEPLLDCDLFSCGFDRRVFGWSIVLP---KDN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ... : :.:. :. .: * * . : : **.* : : :. : *: *. . :.. : : .: *. : ... :: **:* * :*. . * ... **.**:******:.* . . :*:*: **:****:::. ** ::******* : :*.:*:.:**::* **.********* .::.**.*** *****: *: *: . ..: : .*.** * * . * * .* .**:*:*** . .* :*.****:* *:****. ::.*****:**** .:*********:************ :* :*.******:****:**: .*:*********:***:*:****.:*******::**: *... ***:******:****:.* *:*****:.********.. ** *: *:**:*****:.:**.* :* :::", "identical_positions": 212, "similar_positions": 144, "identity": "42.15%" }, { "cls_id": "homologset.agr.HGNC:31407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R521-1", "uniprot_id": "M0R521_RAT", "id": "M0R521-1", "name": "", "aln": "MSQRSLQQGTQGIWVILRGGGECLSPAQLPMSVVKSIEVVLPQDAVYLAGSNIDGQVVLTLNSTLVDPVVKVELVGRGYVEWNEEIG---ETRDYSRDVICNNKADYVHKTKTFP-------------IKDNWLRAGSHTFDFHFNLPPR-LPSTFNSKIGHISYFVQALCMGREHILAKKRLYLLVQGISEFRQRNLSENPLSVEAEKKVSYNCCSRGWVSLHVQMSKNTFVPGEKVTFTSEIRNHTGKYIKTVVFALYAHVQYEGFTPSAERRRRADSSE------------------LLRQMANARIPAFNSTTVVSAFNLPLVLSVS--------------SGSQENEIMRTS----------------------YELVVTIHLPWS-----------------------LSTVKAGLPIIIT------------------SAREDKANCPQVN--ELPY----------EDHLV-----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q497K5-1", "uniprot_id": "ARRD5_MOUSE", "id": "Q497K5-1", "name": "Arrestin domain-containing protein 5", "aln": "------------------------------MSVVKSIEVVLPQDAVYLAGSIIDGQVVLTLNSTLVDPVVKVELVGRGYVEWNEEIG---ETRDYSRDVICNNKADYVHKTKTFP-------------IKDNWLRAGSHTFDFHFNLPPR-LPSTFNSKIGHISYFVQALCLDREHILAKKKLYLLVQGISEFRQRNLSENSVSVEAEKKVSYNCCSQGWVSLHVQMSKNTYVPGEKVTFTSEIRNHTGKYIKTVVFALYAHVQYEGFTPSAERRRRADSSE------------------LLRQMANARIPAFNSTTVVSAFNLPLVLSVS--------------SGSQENEIMRTS----------------------YELVVTIHLPWS-----------------------LSTVKARLPIIIT------------------STREGQADCPRLD--ELPY----------EDHMV-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NEK1-1", "uniprot_id": "ARRD5_HUMAN", "id": "A6NEK1-1", "name": "Arrestin domain-containing protein 5", "aln": "------------------------------MSVVKSIELVLPEDRIYLAGSSIKGQVILTLNSTLVDPIVKVELVGRGYVEWSEEAG---ASCDYSRNVICNNKADYVHKTKTFP-------------VEDNWLSAGSHTFDFHFNLPPR-LPSTFTSKFGHVFYFVQASCMGREHILAKKRMYLLVQGTSTFHKETPFQNPLFVEAEEKVSYNCCRQGTVCLQIQMERNTFTPGEKVVFTTEINNQTSKCIKTVVFALYAHIQYEGFTPSAERRSRLDSSE------------------LLRQEANTPVTRFNTTKVVSTFNLPLLLSVS--------------SSTQDGEIMHTR----------------------YELVTTVHLPWS-----------------------LTSLKAKVPIIIT------------------SASVDSAICQLSEDGVLPVN---------PDHQN-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYX2-1", "uniprot_id": "A0A8M1NYX2_DANRE", "id": "A0A8M1NYX2-1", "name": "", "aln": "--------------------------MQRSIKELSVRYDPINETNTFTNGDIVEGRVVLEVTKEINVENLFVKLTGDADVRWTEGSGD--DERSYSDHERYFKQKQYFIQDSSKKGQCEKNTTLVSGETYGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVK-LKRSWKPTSSAQAEINFAPRNFGTNDHLLQPQSGTEDKKMKLFGS--GKMSMTVTTDKTGYMLGEIIRVSVDIDNSSSRDIKLKYSLKQLQTFIAGRSTTHAHKDIVKETKDCIP-----SGGKTRFVVDIKLPHDIMVTIENCRIIKVQYELKVYLDVS--------------FASDPTVKFPVV----------------------IIPPLQQCPPWHDPPPP-----------------YMPPQPNLVPYPGG------------------AAPPPAGLYPNLYDPVPPYPGTAAGTFPNPNAMLPGFHP--APSAPVYDLNQSTKESFPNAPH------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGU4-1", "uniprot_id": "Q9VGU4_DROME", "id": "Q9VGU4-1", "name": "", "aln": "------------------------------MESERLRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLFYTSKEVYEHSETPLP----------DFEPRGLELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVL-IQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTGGAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEELFGLANAPPGTPK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *. : *.: : :.. : *::.* . .* * .** .: * . .. . : .*.*.* *.. * : :*.:*.. * : * : . : * . : . : . . : : . ** : . : * : :: . . :: : : ::* : : . : . .. * .: * ", "identical_positions": 25, "similar_positions": 72, "identity": "4.45%" }, { "cls_id": "homologset.agr.HGNC:31409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7C4-1", "uniprot_id": "LRC26_RAT", "id": "Q6P7C4-1", "name": "Leucine-rich repeat-containing protein 26", "aln": "MRGSFFSRLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVAPVCPEACSCSPGGKANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAFKQCTQSLAARDLAVVYALGPASFLASLAICLALGSVLTACGARRRRRR-TTVRHLIRRQP----DPEGPASLEDVGSPTTTAIQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W20-1", "uniprot_id": "LRC26_MOUSE", "id": "Q91W20-1", "name": "Leucine-rich repeat-containing protein 26", "aln": "MRGSFFSRLPPQLS----LLLLLSLRRVWTQEDIGTAPSKSPVAPECPEACSCSLGGKANCSALALPAVPADLSWQVRSLLLDHNRVSALPPGAFANAGALLYLDLRENRLRSVHARAFWGLGVLQWLDLSSNQLETLPPGTFAPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSAIEAGLLNNLPALDVLRLHGNPWTCNCALRPLCTWLRKHPRPASETETLLCVSPRLQTLSLLTAFPDAAFKQCTQSLAARDLAVVYALGPVSFLASLAICLALGSVLTACGARRRRRRRTTVRHLLRRQL----DPEGPPSLEDAGSPVTAAIQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2I0M4-1", "uniprot_id": "LRC26_HUMAN", "id": "Q2I0M4-1", "name": "Leucine-rich repeat-containing protein 26", "aln": "MRGPSWSRPRPLLL----LLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLSPLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALRPPRPPDPNPDPDPHGCASPADPGSPAAAAQA-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. :** * * ****** **:* : ** * ** ***.*:* ** *.****:*****..** ::*:****:*** :*******.**** * **** *:***.*******.** ****:****:*.****:***** ********* ***: **.***** ******.*:*: .***. *****.*:*:**** *.*******:***:** *:**:**:*** * **. ** *.* **.:*:*.** *******:***.***.*** ****** **** ***** * :::* : **.* .* * ***.::* ", "identical_positions": 212, "similar_positions": 57, "identity": "62.54%" }, { "cls_id": "homologset.agr.HGNC:31412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63ZV7-1", "uniprot_id": "SWI5_RAT", "id": "Q63ZV7-1", "name": "DNA repair protein SWI5 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MIDEGEEVTEETLNSDIQKLKEKQDMLDKEISQLIAEGYRVIELEQHISLLHEYNDIKDVSQMLLGKLAVTRGVTTKELYPDFDLNPND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3D3-1", "uniprot_id": "SWI5_MOUSE", "id": "Q8K3D3-1", "name": "DNA repair protein SWI5 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MIDENNDVSEEALSSDIKKLKEKHDMLDKEISQLIAEGYRVIELEKHISLLHEYNDIKDVSQMLLGKLAVTRGVTTKELYPDFDLNLND", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1ZZU3-1", "uniprot_id": "SWI5_HUMAN", "id": "Q1ZZU3-1", "name": "DNA repair protein SWI5 homolog", "aln": "MQRRGQRDLWRHNKSCARNRCPRPPRERGGAGFPWVRAQLSVRQFTLRVRVPGPVHLRGRSPTPALDPLAPLNPLIRGPRTPGLRRWIQSLALLLPNCSSSRIPTVPRPHSGLWVQSDFPLGFLSRTEPRLTRSCRGAFRSPRPLPKSGQADGTSEESLHLDIQKLKEKRDMLDKEISQFVSEGYSVDELEDHITQLHEYNDIKDVGQMLMGKLAVIRGVTTKELYPEFGLDMND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FF22-1", "uniprot_id": "E7FF22_DANRE", "id": "E7FF22-1", "name": "DNA repair protein SWI5 homolog", "aln": "-----------------------------------------------------------------------MN------ETAELQMNTQPVS------DDAHVKVTPR-QGGVSSKRRLSE---SRCN---SRSVNSGFKSP----VLKPSMVKSPVCLEEEVKELKKTQDCLDSEIASLEKEGFVVQELDQHIDLLHEYNDIKDIGQTLLGRLAGLRGVTTRDLYSHFGLELDD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::::**:.:* **.**:.: **: * **:.** *********:.* *:*:** *****::**..*.*: :*", "identical_positions": 39, "similar_positions": 26, "identity": "16.6%" }, { "cls_id": "homologset.agr.HGNC:31416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMN4-1", "uniprot_id": "D3ZMN4_RAT", "id": "D3ZMN4-1", "name": "", "aln": "MVLLLLVAIPLLVHSSRGP------THYEMLGRCRMVCDPHASRGQGSDGAPSSVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGPGPGGAAPPAGYVPRIAFYAGLRRPHEGYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGGNTNKYSTFSGFIIYPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4ZJM9-1", "uniprot_id": "C1QL4_MOUSE", "id": "Q4ZJM9-1", "name": "Complement C1q-like protein 4", "aln": "MVLLLLVAIPLLVHSSRGP------THYEMLGRCRMVCDPHASRGQGPDGAPASVPSLPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGPGPGGAAPPAGYVPRIAFYAGLRRPHEGYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGGNTNKYSTFSGFIIYPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Z23-1", "uniprot_id": "C1QL4_HUMAN", "id": "Q86Z23-1", "name": "Complement C1q-like protein 4", "aln": "MVLLLLVAIPLLVHSSRGP------AHYEMLGRCRMVCDPHGPRGPGPDGAPASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGPGPGGVAPAAGYVPRIAFYAGLRRPHEGYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGGNTNKYSTFSGFIIYPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PTL2-1", "uniprot_id": "A0A8M9PTL2_DANRE", "id": "A0A8M9PTL2-1", "name": "", "aln": "MVLILLVTIPLLVHSTKGGGAGTSGSHYEMLGSCRMVCDPYTTS-QGQE--LTAVSPAPPDFP---NRRGKSGYRGPPGPPGPQGPPGEPGKPGPQGPPGPGPGGYVPSF-YSPKIAFYAGLRKQHEGTDVLKFDDVVTNVGNYYEPSTGKFTCPLPGIYFFTYHVLMRGGDGTSMWADLKKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVCVQLDGGKVHGGNTNKYSTFSGFLIYAD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***:*******::* :****** *******: . * : ::*.. **. .****:* *********:*******:*** ********* .*. * *:********: *** :**:********** **.::******:**:***:***************** *********************************** ::********************:**.*", "identical_positions": 178, "similar_positions": 33, "identity": "72.95%" }, { "cls_id": "homologset.agr.HGNC:31418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3J0-1", "uniprot_id": "D4A3J0_RAT", "id": "D4A3J0-1", "name": "", "aln": "MDWPLEDLLRAKGDMGLLQGQLSHALACRHCSSSICLQSPGNLVILFLFMVWQIRRWWQLVGWQQLQPWCSGDKMIQGKGLQLLYHLAFLDYLWKQKS---EEVEDEEKKEEELSLGPLKPYYPSQDTPVGNRFTTAPPQPSCSSKGLPTATETQEQVLKQPPSPSRPFPTFQILTNLPVRNKIASGSSLKQKKSQLFWGLPSLHSESLETIFLSSDGPSPLKLSICPSVFFNKVPFLPVYNLLLPYCHSSAFSPTPEAHTLGDLEEIAPGSQLVQSPPPPPISPVSSNLKPLLKGCKGIISDTEAHTPWFTQNKEAPCISQNQTLYPQPELQTIRSSTFLYSSETWREMPGDPSLHQHNPESPSASLLG---PHEVLDRFEMPWITMDQNEHPTASEAAMPTASPLPTSLTECQRANPTGELPRSKTLWETTVQKENPQACELPNSSPCQLTVPMTEGTGPPGAAPRYEAQWGVLVHKDIPQAFDPLISASCQPSGSLSEVKNVNPKERLSAPKDFRENTGYRKNPPVSKSPVSVPYSPLDTLSEHQKESPLEDLSRFRPQWQCRENSGSPWALETPTLNFNVGFNETTPMRVPLGCETQLKGTPSTENLCVYADLVSSPSLPSTSLPDFTIMGSQRILLESKASLETKEQTDHLWVTESPCP-HIPPLVPFIQSQRINTVNDFPRAETIGSNTEDTRKRLPSEPPFLNLNPSPALAQQPLRVSPIENPFKSEAWSRDTQRENNSLASELPAQRLSQHLLGPSP-AVLSDFESARGFMKQNENHCVSVSPVWDPSPHAHSALKFHVSEPSGDQC-MEAMDSVVER-MDSWANQLPAPSFFPALSQELHSETEFVHRDVLEREASQGPNPPVLNPLQPTCWP-----------IQPGLQKEEMFSEAKAEVPSSQGEAVLEVHGHPVIHAWQWSRELKLRLKKVQQSPTLKDPGSHHSARSSSVLN-LTPESWGLSSCP-QQTHVLSLHPCSSSCHPPKVQSTEPLPVQALHCS--HSS-QPQLQASRRAEQESQKKNKRMKWKAMDQTPSPG-HGHMKAAEN--CSGMGEPSNTRVLVSGKTQDKTPVLLSTQKRGSPRKPKAEKCGR-TARLESSTVTREKNPVWACRPEEASKSRLPEKSQYKAQSSPHTALVQQVLPNTTGPRDRQRSGPVAGDTQNPCPCKHCPWIPRKKQGSSTPILPSSTPKAPPTKGFQKLLDKFLGVHRPLPTKSSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V0E1-1", "uniprot_id": "S31G1_MOUSE", "id": "Q3V0E1-1", "name": "Spermatogenesis-associated protein 31G1", "aln": "--------------MGLLQGQLTHALACRHCSSITCLHSPGNLAILVLFMVWQIRRWWQLRGWQQLQPWCSGDKMTQGKGLQLLYHLAFFDCLWKQKS---EEEEKEEK--ECLSLNPLKPYHLSKDTPIGNGFSTAPPHPSCRSEGRPRATETQEQVLIQSPSPSRSFPTFQTLTNLPVRSKRASGSSPQQTKLQLFSGLPSLYNESLKTIFLSSDGPSPLKLSICPSVFLNKVPFPPAYNLLLPCYHSSTYYPTPEAHILEDLEEIAPGSQLVQSPPSPPIPLVSSNLKPLLKGYKRIIPDTEVHTQWFTQNKEVPSVSENQGLYPQPELQKFRSSTFLYSSEVWRKRPGDLRLHQHNPELPFAFLLYPFNPQEVLDRFEMPWRNMKQNEHPKASETAMPTASPLPISLTECQRVNPTGDLSQVKTLCQTTVQKENLQIYELPISAPCQLTVPVTEGTGPPGTPPGYEAQWGILAYKGIPQASDPLMPASCHPSGSLSKVKNVNPKERLSAPKDVRENLGYREHPHVSKSPVSAPSPPLDTLSDYQRENPPEDGSGFKPQWECKETSGSPWASETPTLDFHVGFYEATPMCVPLGSEAQLKGTPSTENLCVYADIVSSPSLPSVSLPDFAIMGPQRILLESKALWETKEQKKHLWTSDSSCP-HKTPLAPFIGPKRINTVDDVPRSEATGKNTDNTKKCSSSEPPFLNLNPSPALVQQPLRVSPIENPLKSKAWCGHIQRKNNFLASELPAQSLSQHLLEPSPEGVLSDVEPAGGFMK-NKNHCVSASPVWECSPSPNSVLKFHISEPSGDQCNCTPKESVAEWTKDSWANELPGSSFFSALSQEPHSETELVCRNVLEREASQGPNPPAVNPPQPTAWP-----------IQPGL------SEAKAEAPSSQGEAVSEVSDHPVIHAWQWSRQLKLRLNKLQQSPTFKSPGSHHSFSSSPVLN-LTLESWGPSSCS-QQMHPLSLHPCSSSSHPPKVQRAEALPVQAPHCL--HSSSQPQAQASGRAEQRSQK-SKRLKRKAMVQIPSPG-LGHVKADEN--CSGMGEPSDTGLLVSGKRQDKTLVLLSTQKRGSSRKSKAEKCGR-TARLGSPTNTRENNPAQACRPAEASMPRFSRKFEHKAQSSPHSALAQQLLPNAAGPQDRPRTGLVAGETQNPCPFKCCPWIPTKQQ------LSSLSQEAPPTRGFQKLIDKFLGVHRPLPTKSSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VYM1-1", "uniprot_id": "S31G1_HUMAN", "id": "Q5VYM1-1", "name": "Spermatogenesis-associated protein 31G1", "aln": "MEWLLEDLLGAKGDMGLLWGQLTHALACRHCG-SSCFQSPGNLVTLFLFVVWQIQRWWQLGRLRQLHPWCSGN-MVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQ---------------------------------------------------------------------------------------------------------------------------------------------------SPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEME-QKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQR-GEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKY------LSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** ***:********. *::*****. *.**:****:***** :**:*****: * *** * **:::**:* * **** ** *.**: : **.**** ::::* *: :.***:*** *:* * **.: *. ****.** ** **.:*** * ***. :* * *** *****:.***::*****.****** *:*.***:**:.* * ***** ***: .* ** : *** :**..**: .*..*.:. : :*:*: . * ::..:*. * : **.* . * **:: :* :*** :* :...*:...***: ::*.*: *: .**. . ***::* .*:*.:..* .***:*.: *:*.. ** * ::***:*:*.**. ** *:*.*::: : ::* ** ..*: ** * **: * ** **.*****..* : :**.* :* **** ** *..:**.::*. * * .* ..:: .:***. : .. :*: .:*:.::: .*..* * *.*.***. : *** .: .*:* . . *: :* **: ** *.*.* .** .**** :. * *: ::::**.. * ** .:*. * *:*** .**. . ...* : **.:**..* :.: * * : *:* *:* :**..***.* .::* :*. * :*** . .***.* ** :* *: ** ********:*****:*::***: : **. :* **.:*. : ** .**. ** : . * ***.** :** : . ***: ** :** * * * * **** **: .:::* * : * ** * *::* : ..* ****:: :***** :**: . *::** .**.** . * **** .* * :::*. * **. . :..: :::.*** *:** * :**:::**:*: .:* *.: .* * *** :: *. : :*. *:*:**:: * *. ********* ", "identical_positions": 450, "similar_positions": 309, "identity": "36.41%" }, { "cls_id": "homologset.agr.HGNC:31419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPZ9-1", "uniprot_id": "A0ABK0LPZ9_RAT", "id": "A0ABK0LPZ9-1", "name": "", "aln": "----------MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDG----GDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVR------KELKGGKAYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLS------GDPCFKTPPSTAKS---------------------------ISIPGQDSSLQLTCKGGGTSSGGSSSTNSLTGSRPPKAR------------PTILGSG---LAEEPEQSLSSPEEVFHS------------------------------------------------GHSRNSSYASQQSKLSGHS----TEHSRSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTS-----------------SSASGGLSMTVEGPEGSEREHRP---------SEKPPRPPEKPPRPPRP----LHLS--------------------------------------------------------DRSF----RRKKDSVESHP---TWVDDTRIDADDIVEKIMQSQDFTDGSN-TEDSNLRLFVSRDGSTTLSGIQLANRVSSGVYEPVVIESH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T9C2-1", "uniprot_id": "EEIG1_HUMAN", "id": "Q5T9C2-1", "name": "Early estrogen-induced gene 1 protein", "aln": "----------MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDG----GDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCVFRVSVR------KELKGGKAYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLS------GDPCFKTPPSTAKS---------------------------ISIPGQDSSLQLTCKGGGTSSGGSS-TNSLTGSRPPKAR------------PTILSSG---LPEEPDQNLSSPEEVFHS------------------------------------------------GHSRNSSYASQQSKISGYS----TEHSRSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTS-----------------SSASGGLGMTVEGPEGSEREHR----------------PPEKPPRPPRP----LHLS--------------------------------------------------------DRSF----RRKKDSVESHP---TWVDDTRIDADAIVEKIVQSQDFTDGSN-TEDSNLRLFVSRDGSATLSGIQLATRVSSGVYEPVVIESH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q78T81-1", "uniprot_id": "EEIG1_MOUSE", "id": "Q78T81-1", "name": "Early estrogen-induced gene 1 protein", "aln": "----------MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDG----GDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVR------KELKGGKAYSKLGFTDLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLS------GDPCFKTPPSTAKS---------------------------ISIPGQDSSLQLTCKGGGTSSGGSSSTNSLTGSRPPKTR------------PTILGSG---LPEEPDQSLSSPEEVFHS------------------------------------------------GHSRNSSYASQQSKLSGYS----TEHSRSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTS-----------------SSASGGLSMAVEGPEGMEREHRP---------SEKPPRPPEKPPRPPRP----LHLS--------------------------------------------------------DRSF----RRKKDSVESHP---TWVDDTRIDADDIVEKIMQSQDFTDGSN-TEDSNLRLFVSRDGSTTLSGIQLGNRVSSGVYEPVVIESH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RF39-1", "uniprot_id": "A0A8M1RF39_DANRE", "id": "A0A8M1RF39-1", "name": "", "aln": "----------MAFLVKKKKFKFQTHVTLEELTAVPFVNGVLFCKIRLLDG----GDFTASSSREEVHQNCVRWRKRFSFVCKMSANSNTGVLDPCMCRVSVR------KELKGGKAYSKLGFADLNMAEFAGSGWTARCCLLEGYDTKNTRQDNSILKVTIGMTLLS------GDPCFKTPPSTAKC---------------------------ISVAGQDPSLQLDCKGEGT-------AEVLP--RMAKQR------------PSILGSA---LPEEADQSQS-PDESFHT------------------------------------------------GHSRNSSYASQQSKLSGYS----TELSCSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTG-----------------SSVS------ADAP--SESDSR-----------------PDRPPRPPRP----ILPS--------------------------------------------------------SRPP----RRKQDSVEDQP---TWVNDTRIDADDIVEKIVQSQNFSDISN-NEDSNLRLFVSRDGTTALSGIQLGNRVSAGVYEPVVIESH---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VID5-1", "uniprot_id": "Q9VID5_DROME", "id": "Q9VID5-1", "name": "C2 NT-type domain-containing protein", "aln": "MTLLGPSAPGMAFMMKKKKYKFNVEVQLQDLVEVALVNEVLFAKIRLLDG----GSFQEYSSREEVRNHRVEWNRSFEFPCKMSANASTGVLDPCHLRISIR------KEMKGGRSYYKLGFIDLNLAEFAGAGLTSRRFLLEGYDSR-HRLDNSMLRVSIKMHMLS------GDILFKAPTPNLKSKQSKPSIDDFSNAATGVGLQIPTATALPSIGGGSGGASVSLGGSGVTLGGIPGNQSLPGTRPVSTTKEEDIDNQALIAAIVTDSG---LSESSESGVTLTTDNLQQHGSVVVANPISPVTQALPQLGIIGSNNYGTTGGAIGFTGAGNATLIEMGHSRNSSNTSQMSKGSGYSSFSHSQHSRQSSEGDSGHASRQNGQKGDEHQQCNSLRVVVAKSHHVHTHLSLSTTVEYASDEQLYQTPNATMTNSQKLAFEDFRTPMAELAAPLFQPMGAGCSGTPSSTYRSAGSPSHNTQYYDSGEASDTDECLNDESGDNDSGLEENFHTPRVAKIKSMENLSILEMEFHKASMELDRNSPRRLKQLAEHAQIPKMKSLNNLCFDHYAEQSVREEFQRMHEQSLEERMRFQQHHQLRKNSNASNGSATKIYVKHLSHQNHYHIKVGNAKFIGQDGNDSPQSMHYPIQKMRSMGTIQDIVSDRIEPDPFLTPTTERKPNFSRLVQSAEKPVLGSSYVNRLLTYDAVDSPSEPFNSSVSFMSRTPFQRAYRRNIQQGSSSTPLATQDFFAVRPHSTNAAYELMRNFSGVPRRLFDGNITTAGQNSNMGAVSTNRQQQPCAPGTNSFIGSNSSPSGTLASIHSSHSASSSNGSNSSSSGAVITFQCTAGSGQDTVDSANHQQQMTVGSPNGHGSNPRLGNVMSGDVISSMAASPTDACSIRSNPSAASLLLSTSAAAAEASALASATTMSVSGATLSPLATTQIIRRPSITMMNPSSGSLVISETGSLDRTKSSGEKRKKGALDDGPRVSDRVEETRVNPDSLIDEILKDTKLDQLEESAETSGLQLYIARDGTASLGGHEVKSSVRAGALKQVVMQDRR--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38177-1", "uniprot_id": "YBI6_YEAST", "id": "P38177-1", "name": "Uncharacterized protein YBL086C", "aln": "--------MPFNHNSKAKRPKFLLDLQIKELVNIPQSSGYCYTKWRLKDGTGTSGHKVALDGEHQTTSTQSRGTTKHVHVQHHRAQWNYSLDKPILVKLHLDKNGRFLKKILVLDVFFEFADANSSLTSSSSPNGKVKKTTYANATALTATGNNSYSQKITGKLLLGTVDIDITEYVKEDETPTTNR-----------------------FLLKHSKVNSIINVSLQLKLVRGSYEDFNISKSFTNGQLANYRPG---------INTILDNTSELSSPTSTTNQMSPKNTFSN------------------------------------------------FNGIGTTVAKPGTNATGNSTSIKSPTSTNHK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSEMTTKPG--------------------------------------------------------------------------------------------------------------------------------------------------------LSTTIS-----------------SSMSPLIESLYQKTFKLPWDPRPGEFTPRECVEDILQGGNGWAKNEKGINLIDLQALRLN----------------------------------------------EMEEEYYNPNYGNNLGNKASSWPPNPSDDGYSTMGKREYLEKKQNWSHMSRAQRAKLRTHNDEDNENTANDKGSDKDNNSVEDNNPTDFLTDRIRENKNWSIITPSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *: ** . :::*. :. . : * ** ** * ....:. . . . . : *: .: .* :: : *:: : ::. : .::. :... . : . : :** : :*. : : ... : * . . .: : :. : . : .. . . . . : : :. .:: :. :: :* * : * . . : * : .:: . .* . . : * : . .* .: * : : :: : . . . . :.* : .. .: :. : :.: ", "identical_positions": 27, "similar_positions": 127, "identity": "2.53%" }, { "cls_id": "homologset.agr.HGNC:31420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LHV7-1", "uniprot_id": "A0ABK0LHV7_RAT", "id": "A0ABK0LHV7-1", "name": "", "aln": "MMPVSRRNLDWTYSSLLLAIVLLSWGFVIYASTVAARWQLQKEFPDKFF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LHV9-1", "uniprot_id": "TZMP1_MOUSE", "id": "A0A140LHV9-1", "name": "Transition zone microprotein 1", "aln": "MRPMSRRSLDWTYSLLLLAIVLLSWGFVIYASTVAARRQLQKEFPDKFF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1B0GUW7-1", "uniprot_id": "TZMP1_HUMAN", "id": "A0A1B0GUW7-1", "name": "Transition zone microprotein 1", "aln": "MKPVSRRTLDWIYSVLLLAIVLISWGCIIYASMVSARRQLRKKYPDKIFGTNENL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:***.*** ** *******:*** :**** *:** **:*::***:* ", "identical_positions": 34, "similar_positions": 9, "identity": "61.82%" }, { "cls_id": "homologset.agr.HGNC:31421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRD5-1", "uniprot_id": "D3ZRD5_RAT", "id": "D3ZRD5-1", "name": "", "aln": "MRDLWILLFLPLFLAAFHGVKGCLECDPKFTEDVRILLENLVPLEVPERNQLLERQHKEITHISSKVSHKDKMLRLLAVRNVVKLRVWLKDEFYRLGNETWKGVFIIRGKLLAVRQNLENKLTQILKNFSEVACSEDCIVTEGPVLDCWTCLRMTTRCFRGEYCQDDDPREAENREISLYLIFTAEAVILASAVLLFHVCVTHRRKMRQIRRTLKTYLEKKLEELVEIIYKDE-KKDSEFGKSNTQSLTGQPPNAESEMKTGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6PWV3-1", "uniprot_id": "IZUM3_MOUSE", "id": "A6PWV3-1", "name": "Izumo sperm-egg fusion protein 3", "aln": "MGDLWVLLFSSLSLAAFHGVRGCLECDPKFTEDVRTLLGNLVPLEVPDRNQLLDRQHKEITHISSKVSHKDKMLRLLAVRNVIKLREWLKDEFYRLGNETWKGVFIIQGNLLEIRQNLEKKLTQIIKNFSEVACSEDCIVIEGPVLDCWNCLRMTTRCFKGDYCQDEDPKTAENREISLYLIFIAEAVILASAVLLFHVCISHRRKMKAIRRTLKTYLEKKLEELVEMIYKDDGEKNLEFGRSNSNSLTGEPTCAESEMQTGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZ72-1", "uniprot_id": "IZUM3_HUMAN", "id": "Q5VZ72-1", "name": "Izumo sperm-egg fusion protein 3", "aln": "MGDLWLFLLLP--LSAFHGVKGCLECDPKFIEDVGSLLGNLIPSEVPGRTQLLERQIKEMIHLSFKVSHSDKRLRVLAVQQVVKLRTWLKNEFYKLGNETWKGVFIYQGKLLDVCQNLESKLKELLKNFSEIACSEDCIVVEGPILDCWTCLRMTNRCFKGEYCGDEDPRKAENREIALFLILLATAVILGSAVLLFHFCIFHRRKMKAIRRSLKEYVEKKLEELMGKIDEKE-EKDFRLRK---------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***::*: . *:*****:********* *** ** **:* *** *.***:** **: *:* ****.** **:***::*:*** ***:***:*********** :*:** : ****.**.:::*****:******** ***:****.*****.***:*:** *:**: ******:*:**: * ****.*******.*: *****: ***:** *:*******: * :.: :*: .: : ", "identical_positions": 158, "similar_positions": 52, "identity": "60.08%" }, { "cls_id": "homologset.agr.HGNC:31422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWG8-1", "uniprot_id": "D3ZWG8_RAT", "id": "D3ZWG8-1", "name": "", "aln": "MGTFNSSCHECFKRKERWYEIGPTDLLERKGSLTLRSQDKKYSGPVLVYSWHRNREAFPKDYDMEDPKVATNLCKSTYHRLGTD-SPRWVSEAQEQMSQVLVNKDFLEKKKKALVHDETMCLGILESDPQLLPSGFREASMEPPPDPRKQCYSTTYSEDYVPQYEYPPPACPLQDDYSIVHRKCRSQFTDLNGSKRFGINKWHDESGIYANSKAKQKLYALAGNPIVPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQC3-1", "uniprot_id": "CFA95_MOUSE", "id": "Q9CQC3-1", "name": "Cilia- and flagella-associated protein 95", "aln": "MGTFDSQCHECFESKERWYEIGPTDLLERKGSLTLRSHHKKYSEPVLVYSWHRNREAFPKDYDIESLETVKNLCMSTYKRFGSD-SPRWMSEAREQMAQVLVNKDLVEKKKTGLLDEETLCPGILERDPELPPTGFRDVPMESPPDPRKPCFSTTYSEDFTPQYEYPPPACPRREEYSIVHRKCRSQFTDLNGSKRLGINTWHDESGIYANSEAKQKLYALARNPIVPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTT2-1", "uniprot_id": "CFA95_HUMAN", "id": "Q5VTT2-1", "name": "Cilia- and flagella-associated protein 95", "aln": "MDSLDRSCQDWCDRKQHWLEIGPPDLVERKGSLTLRSHHKKYSKPVLVYSWHRDREAFPKGYDIEGPEKVKKLCNSTYRRLGTDESPIWTSETHEKLSQMCLNTEWVEMKSKALLNEETVSSGIIERVTGLPATGFGAVFPRHPPDWSKMCALTTYSEDYVPPYDYQPHAYPCQDDYSIVHRKCRSQFTDLNGSKRFGINTWHDESGIYANSDVKQKLYPLTSGPIVPI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.::: .*:: . *::* ****.**:**********:.**** *********:******.**:*. : ..:** ***:*:*:* ** * **::*:::*: :*.: :* *...*:.:**:. **:* . * .:** . . *** * * ******:.* *:* * * * :::********************:***.***********..*****.*: .****:", "identical_positions": 130, "similar_positions": 63, "identity": "56.77%" }, { "cls_id": "homologset.agr.HGNC:31428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4J1N3-1", "uniprot_id": "GP15L_MOUSE", "id": "A0A0B4J1N3-1", "name": "Protein GPR15LG", "aln": "MRLLALSGLLCMLLLCFCIFSSEGRRHPAKSL---KLRRCCHLSPRSKLTTWKGNHTRPCRLCRNKLPVKSWVVPGALPQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZKM3-1", "uniprot_id": "GP15L_RAT", "id": "D3ZKM3-1", "name": "Protein GPR15LG", "aln": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFP---KLRPCCHLSPRSKPITWKGNHTRPCRPCR-KLESNSWVVPGALPQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWK7-1", "uniprot_id": "GP15L_HUMAN", "id": "Q6UWK7-1", "name": "Protein GPR15LG", "aln": "MRLLVLSSLLCILLLCFSIFSTEGKRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.**.*: :*:**:.::*:**:::*** : * *** * .: . **:*.* *: *: : . *********:", "identical_positions": 36, "similar_positions": 24, "identity": "44.44%" }, { "cls_id": "homologset.agr.HGNC:31440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUE3-1", "uniprot_id": "A0ABK0LUE3_RAT", "id": "A0ABK0LUE3-1", "name": "", "aln": "MLQQILQDMYIDPELLAELSDVQKHILFYKMREEQLRRWRERE-AWDALAQAEGLRPAKVKRASNKHIQWLLGADGEVWVWVMGEGPGDKPYEEISEELIAERARLQAQKEAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKVLEE--RIHEEFKRKEEEERRRGEEQIRLQEEQRAKELYWTLKQAQLHCQDSENEEREWEEQLRRSKAADEERSRRAQRARDEYRRHSLRAIQKGTVAGLSTMFQELGQN------------------------------HEQEARLYHQLPGTRPPSP----LTGPDRTWERPLRPLSREVIVRWFKEEQLPRRAGFERNTKSIAPWFHGIISRENAEDLLENMTEGAFLVRVSEKIWGYTLSYRLQRGFKHFLVDASGDFYSFLGVDPNRHATLTDLIDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6X942-1", "uniprot_id": "SH24B_MOUSE", "id": "A6X942-1", "name": "SH2 domain-containing protein 4B", "aln": "MLQQILQDMYIDPELLAELSDVQKHILFYKMREEQLRRWRERE-AWDALAQAEGLRPAKVKRASNKHLQWLLGADGEVWVWVMGEGPGDKPYEEISEELIAERARLQAQKEAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKILEE--RIHEEFKRKEEEERRRGEEQIRLQEEQRAKELYWTLKQAQLHSQASENEEREWEEQLRRSKAADEERSRRAQRARDEYRRHSLRAIQKGTVAGLSTMFQELGQN------------------------------HEQEARLYHQLPDTSPPSP----LTGPDRTWERPLRPLSREVIVRWFKEEQLPRRAGFERNTKSIAPWFHGIISRESAEDLLENMTEGAFLVRVSEKIWGYTLSYRLQRGFKHFLVDASGDFYSFLGVDPNRHATLTDLIDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SQS7-1", "uniprot_id": "SH24B_HUMAN", "id": "Q5SQS7-1", "name": "SH2 domain-containing protein 4B", "aln": "MLQQILHDMYIDPELLAELSDVQKHILFYKMREEQLRRWKERE-TWEALAQDEGLRPPKTKRASDKHIQWLLGADGEVWVWIMGEGPGDKPYEEISEELIAERARLQAQREAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKVLEE--RIHEEFKRKEEEERKRGEEQIRLQEEQRAKELYWTLKQAQLHCQASEKEEREWEEQLRRSKAADEERSRRAQRARDEYRHHSLRAIQKGTVAGLSSMFRELGQS------------------------------HEQEARLYHHLPDPGLPQP----LALPVRTWERPLRPVSRDVIVRWFKEEQLPRRAGFERNTKFIAPWFHGIISREDAEALLENMTEGAFLVRVSEKIWGYTLSYRLQKGFKHFLVDASGDFYSFLGVDPNRHATLTDLVDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RKL1-1", "uniprot_id": "A0A8M1RKL1_DANRE", "id": "A0A8M1RKL1-1", "name": "", "aln": "MMQQILRDMFVDPELLAELNEEQKQILFYKIRQEQVRRWTACEGSWENPLVKE-------RDESRKSVQWLQGRDGEVWVWVMGDAPGDKPYELIVKELMEERARRQAQLEAQELWRRKEEEIKQKFRHAITKEKARLVAGKWKEEAEDRKAAKQEEE--RIQEKLKKQEEEERQREEEEIRRAEEKRAKELYMSLEQEQ---KKSEQRDKAWEEHLCRCKAADEEMTRKACWARDEYKRQSLRAIEKGHVAGLSGHFQKQSQ------RRHSAFIEPSASPVSSNEVRPKPGLQRAEPPLYRRRQSRRHSTTTTTQPLMDSPAWLQTPRPGSRELVILWFNEEQKPKQAGYERNGKAIAPWFHGIISREDSETLLMNAAVGSFLVRVSERIWGYTLSYRTASGFKHFLIDASGDYYSFLGVDQNRHATLADLIDFHKEEIITTTGKELLLEACTRTGPSKDFGGLLP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QES0-1", "uniprot_id": "A0A8M9QES0_DANRE", "id": "A0A8M9QES0-1", "name": "", "aln": "MMQQILQEMYIEPDLLAELSEEQKQILFYKIRQEQVRRWNERE-RRDQSSAGK-------KKSNRRGIQWLLGSDGEVWVWVMGDALGDKPFEDIVEELMEERARKQAQREAQELRRVKEAEIEKKFRDAMAKEKARFAAEKWKEETDDRKAAKQEEEEDRIREELKKCEEEERQRGEEEIRQTEEKRAKELYISLKQEE---KRNERDDKEWQEQLRRSKAADEEMKCKARRARDEYKRQSLRAAEKGLVAGLSGLFHKTHLNGSGHNRRHGTAAEHSSPSAEASHSHATSAGQLTSG-HYRHRQHHRYSSP-VTQSLTECPVWIRPTRPNSRESIIRWFKEEQRPKRAGYERSSNTIAPWFHGIISRQESEALLTNAVEGSFLVRVSERIWGYTLSYRNPSGFKHFLIDASGDHYNFLGVDQNRHATLADLINFHKEEVITTSGGELLQDPCRPRSSAADHGGLFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:****::*:::*:*****.: **:*****:*:**:*** * : : : . : :*** * *******:**:. ****:* * :**: **** *** **:** * ** ** :***.*:::****: * *** * :****** ** **:*::*: *****:* **:** **:****** :*:* : : .*. :: *:*:* *.****** . :* *****:::**** :** ***** *:: : . *:: . . .* :. ** **: :: **:*** *::**:**. : ***********:.:* ** * . *:*******:********* ******:*****.*.***** ******:**::*****:**.:* *** :.* ... *. *: ", "identical_positions": 224, "similar_positions": 99, "identity": "47.86%" }, { "cls_id": "homologset.agr.HGNC:31446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ATY4-1", "uniprot_id": "A2ATY4_MOUSE", "id": "A2ATY4-1", "name": "", "aln": "MESTLEECNSRLRFVSGEMDNSSFIQFDVPEHSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPSVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTIGAEENPE--SRNGVKDGSFFTNPVEISPPYCPQVRQPPVSSDLRMETTPNKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGAYGSVLQHA-YPYSQTASQPSSVPEAFGGQTNSSPSRSMLSCFRGRGARQKRALSVHLHSDLQGVVQGSDSEAMMNNPGYESSPRERSARGYWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEVCGKCFPFQGTLNQHLRK----------NHPGVTEGRGRMESPERTDMYVEQKLESDASASEMALDSRLEMHTVSDAPD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LW70-1", "uniprot_id": "F1LW70_RAT", "id": "F1LW70-1", "name": "", "aln": "------------------MDSSSFIQFDVPEHSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPSVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTIGAEETPE--SRNGVKDGSFFTSPVEISPPYCPQVRQPPVSSDLRMETTPNKALRSRLQEEGHSDRGSSGSVSEYEVQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGTYGSVLQHA-YPYSQAASQPSSVPEAFGGQTNSSPSRSMLSCFRGRGARQKRALSVHLHSDLQGVVQGSDSEAMMNNPGYESSPRERSARGYWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEVCGKCFPFQGTLNQHLRK----------NHPGVTEGRGRMESPERTDVYGEQKLESDASASEMALDSRLEIHTVSDAPD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCN2-1", "uniprot_id": "ZBT34_HUMAN", "id": "Q8NCN2-1", "name": "Zinc finger and BTB domain-containing protein 34", "aln": "------------------MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPE--SRNGVKDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHA-YSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRK----------NHPGVAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V1A3-1", "uniprot_id": "B0V1A3_DANRE", "id": "B0V1A3-1", "name": "", "aln": "-----------------MEDCGSLIEFDVPEFSNTVLNQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSSLGTMSGLSISVIKSPEVFEQLLAFCYTGRMALRLRDVISFLTAASFLQMQAVIDKCTQILEGIHSKISIPASGEIDPDNECTTSRAGRNGVKDRGIFVNPTEISPSHFS--RQ-----NHCME---GQSSGKGIAEEGQSDRGSSDSISEQEASMEVESEQVELIGKDGQVTDVHIKLEKTDRPSYSDSSSAGDDGYHTELVDGEQVLAVSVGSYMPVLSSVGYTYSALPSS------CFVSLSSSSPSRSLLSSVRGGRARPKRPVPLPVDMLTQPKPGADEGEPPATTATFENDVRERSLRGQWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDNKPFHCQICGKCFPFQGTLNQHLRKKHMTSGTEINNHTDLLEEAPDGQRGEQEDISEGEAACGAAYPDDLSKKSPSEESGKCSPEEPPASKLLRGY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*:*:*****.*.***.*****************************************:*.***********.*.******:*******:*:*:**:************.**********.******: ..: . * ... .****** .:*..*.****.: . ** : ** .:: . : ***:******.*:** * .:* : ** :*: ::.*:*:*::*:**:**** ***** ********:******:**.**:* .**. . *.** .*. .* . :.******:**..** ** **.:.: :. * ..:.*. ... :*.. **** ** ************************************************************:***:*::***************** **..: * : *: *: : . * ..::. .* * ... : ", "identical_positions": 298, "similar_positions": 113, "identity": "55.08%" }, { "cls_id": "homologset.agr.HGNC:3145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P69744-1", "uniprot_id": "TRPV5_MOUSE", "id": "P69744-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "--------------------------------------------------------MG-----AKTPWIQLQKLLN-WWVRDQDWNQHVDQLHMLQQK---SIWESPLLRAAK----------------ENDMCTLKKLQHDQNCDFRQRGALGETALHVAALYDN---LDAAIMLMEAAPYLVTESTLCEPFVGQTALHIAVMNQNVNLVRALLARGASAS-------ARATGSAFHRSS---------------HNLIYYGEHPLSFAACVGSEEIVRL-LIEHGADIRAQDSLGNTVLHILVLQPNKTFACQMYNLLLSYDG-GDHLKSLELVPNNQGLTPFKLAGVEGNTVMFQHLMQKRKRIQWSFGPLTSSLYDLTEIDSWGEELS------FLELVVSSKKKEARQILEQTPVKELVSLKWKKYGQPYFCLLGALYIFYMVCFTTCCVYRP-----------------------LKFRDANRTHVR-DNTIMEQKSLQEAYVTYQD---------------------------KIRLVGELVTVIGAVIILLLEIPDIFRVGASRYFGQTVLGGPFHVIIITYASLVLLTMAMRLTNVNGEVVPMSMALVLGWCS-VMYFARGFQMLGPFTIMIQKMIFGDLLRFCWLMAMVILGFASAFYIIFQTEDPDNLG-----EFSDYPTAMFSTFELFLTIIDGPANYR-----VDLPFMYSVTYATFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICG-------CEYGLGDRWFLRVEHHQEQNPYRVLRYVEAFKSSDKEEVQEQLSEKQPSGTETGTLARGSVVLQTPPLSRTTSLSSNSHRGWEILRRNTLGHLNLGLDPGEGDGEEIYQF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JIP0-1", "uniprot_id": "TRPV5_RAT", "id": "Q9JIP0-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "--------------------------------------------------------MG-----VKKPWIQLQKRLN-WWVREQDWNQHVDQLHMLQQK---SIWESPLLRAAK----------------ENDMCTLKRLQHDQNCDFRQRGALGETALHVAALYDN---LDAAIMLMETAPYLVTESTLCEPFVGQTALHIAIMNQNVNLVRALLARGASAS-------ARATGSAFHRSS---------------HNLIYYGEHPLSFAACVGSEEIVRL-LIEHGADIRAQDSLGNTVLHILVLQPNKTFACQMYNLLLSHDG-GDHLKSLELVPNNQGLTPFKLAGVEGNTVMFQHLMQKRKHIQWSLGPLTSSIYDLTEIDSWGEDLS------FLELVVSSKKKEARQILEQTPVKELVSLKWKKYGQPYFCLLGMLYIFYMICFTTCCVYRP-----------------------LKFRDANRTHVR-DNTVLEQKPLQEAYVTYQD---------------------------KVRLVGELVTVIGAVVILLIEIPDIFRVGASRYFGHTVLGGPFHVIIITYASLVLLIMVMRLTSMNGEVVPISMALVLGWCS-VMYFSRGFQMLGPFTIMIQKMIFGDLLRFCWLMAMVILGFASAFYIIFQTEDPESLG-----EFSDYPTAMFSTFELFLTIIDGPANYS-----VDLPFMYHLTYFAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICG-------CEYGLGDRWFLRVEHHQEQNPYRVLRYVEAFKSSDKEEVQEQLSEKQPSGTETGTLARGSVVLQTPPLSRTTSLSSNSHRGWEILRRNTLGHLNLGQDLGEGDGEEIYHF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQA5-1", "uniprot_id": "TRPV5_HUMAN", "id": "Q9NQA5-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "--------------------------------------------------------MGGFLPKAEGPGSQLQKLLPSFLVREQDWDQHLDKLHMLQQK---RILESPLLRASK----------------ENDLSVLRQLLLDCTCDVRQRGALGETALHIAALYDN---LEAALVLMEAAPELVFEPTTCEAFAGQTALHIAVVNQNVNLVRALLTRRASVS-------ARATGTAFRHSP---------------RNLIYFGEHPLSFAACVNSEEIVRL-LIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRRHIQWTYGPLTSILYDLTEIDSWGEELS------FLELVVSSDKREARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLYMICFTTCCVYRP-----------------------LKFRGGNRTHSR-DITILQQKLLQEAYETRED---------------------------IIRLVGELVSIVGAVIILLLEIPDIFRVGASRYFGKTILGGPFHVIIITYASLVLVTMVMRLTNTNGEVVPMSFALVLGWCS-VMYFTRGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPTSLG-----QFYDYPMALFTTFELFLTVIDAPANYD-----VDLPFMFSIVNFAFTIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKLPRCLWPRSGICG-------CEFGLGDRWFLRVENHNDQNPLRVLRYVEVFKNSDKEDDQEHPSEKQPSGAESGTLARASLALPTSSLSRTASQSS-SHRGWEILRQNTLGHLNLGLNLSEGDGEEVYHF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QN56-1", "uniprot_id": "F1QN56_DANRE", "id": "F1QN56-1", "name": "", "aln": "--------------------------------------------------------MP---PAISGEINHWWRQMRFRLQHKKGWNEMLDETFLMQTK---RVNDIPLFSATK----------------ENNAACIKKLLDCSSTDIFERGELGETALHVAVMNDN---FEAAVALMNGAPELINEPMTSELYHGLTALHIAVINQNPNLIWEMIKRGADVTT------PRVTGMYFRKRR---------------EGLFYYGEHILAFAACVGNKDIMSM-LIKAGANIRAQDSRGNTILHLLVLQPNKTTACQIFDFLLAQDAEQDSALPLDMVPNYKGLTPFKLAARDGNVVVFQHLVNRRKVVQWSLGPVSSYLYDLTEIDSRVDEHS------VLEIIATSHKKEARRILELTPVRQLITLKWNLYGKHYFRSLMVIYLVYISIFTVCCINRP-----------------------LKGIPENYTKAGNDHTIKIKKTFKESYQSYTD---------------------------QLRLIAEIISLIGAIIILLIEIPGILAVGVKRFFGQTALGGLFHVTLISYALLVLLLCGLRVTGIQGELIPMAFSLILGWFS-LVYFARGFEMLGPYVIVIQKSIFGDITKFMWLSIIFLIGSSAALWIFYMTQEPLALP-----QYRSFPITLFSQFEVSVGQIDLPVDHT-----LFTHPVVYWTHVCFSLISNVLLFNLLVAMMSDTQWRVTQERDELWRTQVVATTLMLERKLPQCLWPRLGVCG-------LMFGLGERWYLRVEDRNDIMAQKLKRYVDAFS-----KDVEAPKEEKPSKSDG----------EQSIAESNKEKSKKSKQYWSLIRR------SIECEKEECVDCPNFKFL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PI57-1", "uniprot_id": "M9PI57_DROME", "id": "M9PI57-1", "name": "", "aln": "---------------MGNTESNVTSGVKKQAGVSTQALYKFVNLKGGGLLVDMMKRACQTKQFAEIDHAIKTKVEPFLYNKGAGRYFPISKLVLLRNRDRPRTRQLPEIRALENPDDDFNIHDYCPEVSEAEYISNPTAYRFVCWDLNMRGAVGETILHLCLLNASSLHADLAKRLLKFYPKLILDIYMSDEYYGESVLHIAIVNEDPAMVKYLLDANADVQERCCGAFMSAEDTKFSRTDSPDHEYVALCPMTNYDGYVYWGEYPLSFAACLSQEECFRL-VLARGADPDFQDTNGNTVLHMLVIYEK-----------IEMFDVGYEVGTNIHIKNIQNLTPLTLAAKLGRVEMFFHVMSIEREIYWQLGSITCAAYPLLMIDTINEETGNINKDSVLNFVVFGDKLEHLELLDG-VVIDLLKTKWDTFCKSRFYKQFYMFALYFLISLFSFILRPGPDAKDEDEDGANSTTAKSDLYRQNGSDSYHLHSKRATMTTEYKTFWLNFTEYYDPSEVEVLPAWWESYAQCPLMNLESDLAKLRIMAELLNFVGAILYLLVALREARFLGLKMFIEN-LMTAPSRVMFLFSCALMMTIPWLRVSCLTEIDDHVTVVIMLTTAPYFLFFCRGFKTVGPFVVMIYRMVMGDLLRFVSIYLVFVMGFSQAFYIIFLTFDNPSSPEDQDAESNPMPSPMESIVAMFLMSLTNFGDYYGAMVSTQHEYEAKILFFLFMVIVSVLLVNMLIAMMGNTYQKIAEIRN-EWQRQWARIVLVVERSVPPAERLKNFMQY-------SQSMSDGRRALVLRLNMTEEEKEEMKEVQEMKR---------------------------------IHQRFAKKRQMEREARALRRQQEYEKFFGTAPKSECSDNNNF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3W0-1", "uniprot_id": "Q9W3W0_DROME", "id": "Q9W3W0-1", "name": "", "aln": "MKFLLKKCLRKKAPEMKPGAILDAVISQSSATACKCLLYKLADYKRGGDLIDAINSGG----LIAVEQLIREQFGVFMYNDGKGQVINRAEFLRWKYR-DHTEVTIPIEASLS-----------------IHDPLGKWEDHKACWQMQYRGALGESLLHVLIICDSKVHTKLARVLLRVFPNLALDVMEGEEYLGASALHLSIAYSNNELVADLIEAGADIH-------QRAIGSFFLPRDQQRAN---PAKSTDYEGLAYMGEYPLAWAACCANESVYNL-LVDCGSDPDAQDSFGNMILHMVVVCDKLD--------MFGYALRHPKTPAKNGIVNQTGLTPLTLACKLGRAEVFREMLELSAREFWRYSNITCSGYPLNALDTLLPDGRTN-WNSALFIILNGTKPEHLDMLDGGIIQRLLEEKWKTFAQNQFLKRLLILSTHLLCLSVSVYLRPAHDG------------------EAEDEDSEGSDASAAALLDIQSDEGDSGGGDYN------------------------AQTVARYCAEFATLVGVLSYVIFQQGDEIKNQGLSAFLKQLSHAPAKAIFLFSNLLILACIPFRLIGDTDTEEAILIFAVPGSWFLLMFFAGAIRLTGPFVTMIYSMITGDMFTFGIIYCIVLCGFSQAFYFLYKGHPQVQST-----MFNTYTSTWMALFQTTLGDYNYPDLNQ-----TTYPNLSKTVFVIFMIFVPILLLNMLIAMMGNTYVTVIEQSEKEWMKQWAKIVVTLERAVPQADAKGYLEAYSIPLGPSDDSGFEVRGVMVIKSKSKTRAKQRKGAVSNWKRVG-RVTLTALKKRGMTGEEMRRLMWGRASISSPVKVTKQKLKDPYNLHTDSDFTNAMDMLTFASNPASSNGVTLRSVTAPPPAPPAPDPFRELIMMSDQRPETHDPHYFAGLQQLANKAFDLVEQTMKTQPQAPVAKKVDPLPVASVAKASPAAPATQATATAAAASDLMAMPLPISNLSNLFQDPKDIVDPKKLEEFMAMLAEVETEESDSGGPILGKLSLAKRTHNALSKAEIRRDQQGFEGHSHGQFQPMSSVWAPPGLDVDTGFHFDEAVAEEVLTIEQEAEVETEDGNGGQDSEDIPTAEEVHATMKQFHLRKCQPAQDEAARRAKSARVRRRNKVSPEQSDDPDERSQRGRSAYTRRTQSPPDPLEPWSTRELQDINKILARK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12324-1", "uniprot_id": "YVC1_YEAST", "id": "Q12324-1", "name": "Calcium channel YVC1", "aln": "--------------------------------------------------------------MVSANGDLHLPISNEQCMPENNGSLGFEAPTPRQILRVTLNLKYLIDKVVP----------------------IVYDPNDIVCDHSEILSPKVVKLAYEACGGNPKDKANKRKYQSVIIFSLLKVCEWYSILATMEVHNAKLYETRNLASQQLCKLLIER-------EETRDLQF----------------------LFMQLLLRRYVINENDEDQEPLNALELATDMHCTTVIGSSGFQRCLKWIWRG--------WIVQNGLDPTTFIKDDSLAEVSLISHFNPVRLKAPVYQNYLQMIFSFLFLGLYTLVVNGKDSERVQSFDLLES--------IFYVFNTGFILDELTKLYYIGYAHLSFWNLFNDTTYLIITFAMGFRAMSVTPLNAKYSS---------------------EDWDKISYRVLSCAAPFVWSRLLLYLESQRFIG-----------------------------IMLVILKHMMKESIVFFFLLFLIMIGFTQGFLGLDSADGKRDITGPILGNLTITVLGLGSFDVFEEFAPPYAAILY-----YGYYFIVSVILLNILIALYSTAYQKVIDNADDEYMALMSQKTLRYIRAPDEDVYVSP------LNLIEVFMTPIFRILPPKRAKDLSYT----------VMTIVYSPFLLLISVKETREARRIKYNRMKRLNDDAN-EYDTPWDLTDGYLDDDDGLFSDNRNSGMR--------ATQLKNSRSLKLQRTAEQEDVHFKVPKKWYKN----------------------VKKCSPSFEQYDNDDTEDDAGEDKDEVKELTKKVENLTAVITDLLEKLDIKDKKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * . . . :* : . : : . . * : :. .:. : : .:: *. :: : : .* . . : : ::: : . : . : *. : : . . : .: .:. : . * : : : :: : .: : : . :: . . * :: : . : : : : : : :: : :. . . . . . . . ", "identical_positions": 8, "similar_positions": 92, "identity": "0.66%" }, { "cls_id": "homologset.agr.HGNC:31452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJW5-1", "uniprot_id": "LUR1L_RAT", "id": "Q5BJW5-1", "name": "Leucine rich adaptor protein 1-like", "aln": "MEDGPLPDLRDIELKLGRKVPESLARSLRGEEPAPREGAADPSG-------VGGSCSSSSSCSSFAPSVSSSSSSSPASGSPRRSHPSALERLETKLHILRQEMVNLRATDVRLMRQLLLINESIESIKWMIEEKATVTSRGSSLSGSLCSLLESQSTSLRGSYNSLHDGSDGLDGISVGSYLDTLADDVPGHQTPSDLDQFSDSSIIEDSQALHKHPKLDSEYYCFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2P1-1", "uniprot_id": "LUR1L_MOUSE", "id": "Q8K2P1-1", "name": "Leucine rich adaptor protein 1-like", "aln": "MEDSPLPDLRDIELKLGRKVPESLARSLRGEELAPREGAADPSG-------VGGSCSSSSSCSSFAPSVSSSSSSSPASGSPRRSHPSALERLETKLHILRQEMVNLRATDVRLMRQLLLINESIESIKWMIEEKATITSRGSSLSGSLCSLLESQSTSLRGSYNSLHDGSDGLDGISVGSYLDTLADDVPGHQTPSDLDQFSDSSIIEDSQALHKHPKLDSEYYCFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IV03-1", "uniprot_id": "LUR1L_HUMAN", "id": "Q8IV03-1", "name": "Leucine rich adaptor protein 1-like", "aln": "MEDSPLPDLRDIELKLGRKVPESLVRSLRGEEPVPRERDRDPCGGSGGGGGGGGGCSSSSSYCSFPPSLSSSSSSSPTSGSPRGSHSSALERLETKLHLLRQEMVNLRATDVRLMRQLLVINESIESIKWMIEEKATITSRGSSLSGSLCSLLESQSTSLRGSYNSLHDGSDGLDGISVGSYLDTLADDVPGHQTPSDLDQFSDSSLIEDSQALHKRPKLDSEYYCFG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.********************.******* .*** **.* **.****** .**.**:********:***** **.***********:********************:*****************:********************************************************************:*********:***********", "identical_positions": 199, "similar_positions": 15, "identity": "87.28%" }, { "cls_id": "homologset.agr.HGNC:31454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69AB2-1", "uniprot_id": "TXND8_MOUSE", "id": "Q69AB2-1", "name": "Thioredoxin domain-containing protein 8", "aln": "MVKRIKNMSELKELFSDAGNKLVVVEFSAKWCGPCKTIAPVFQAMSLKYQNVTFAQVDVDSSKELAEHCDITMLPTFQMFKYTQKVTPFSRLKRVLCCLRSGPKSKMIFECHGADAKQLEKKIQELM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69AB1-1", "uniprot_id": "TXND8_RAT", "id": "Q69AB1-1", "name": "Thioredoxin domain-containing protein 8", "aln": "MVQKIKSMREFKELLGAAGNRLVVVEFSAQWCGPCKMIAPAFQAMSLQYRNVMFAQVDVDSSQELTEHCSIQVVPTFQMFKHSRKVTPFSRLKRILCCFRSGPGSKKIFEFQGADIEKLEEKIQELM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A555-1", "uniprot_id": "TXND8_HUMAN", "id": "Q6A555-1", "name": "Thioredoxin domain-containing protein 8", "aln": "MVQIIKDTNEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQNVFFANVDVNNSPELAETCHIKTIPTFQMFKKSQKVTLFSRIKRIICCYRSGFMSNLIFEFCGADAKKLEAKTQELM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: **. *:* :: **::*.**:**:: ***** : *.*:***::*:** **:***:.* **:* * * :******* ::*** ***:**::** *** *: *** *** ::** * ****", "identical_positions": 71, "similar_positions": 30, "identity": "55.91%" }, { "cls_id": "homologset.agr.HGNC:31455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4N9-1", "uniprot_id": "D4A4N9_RAT", "id": "D4A4N9-1", "name": "", "aln": "MRMKGLACPCPALPKFLELGTSLMAEGSRAQASGQGPPINIQFLRAQYEGLKRQQRTQAHLMVFPKEGIMPAPAELMTSTVWINKERRSSLSPEETDSEAEGMLEEADRSCRQAP---WHTYLELHRLVQTFHLEAGHQGNPKGYLVEPEPRLSPEGDTDVLKSSQKTHQEIKISEVAQRQGQGDRAPLQVAGS----SAQGLASTKNLHRSGKPAHYPFPQRKPPRISQAARNLGLYGPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JTZ5-1", "uniprot_id": "CI152_HUMAN", "id": "Q5JTZ5-1", "name": "Uncharacterized protein C9orf152", "aln": "--MEGLPCPCPALPHFWQLRSHLMAEGSRTQAPGKGPPLSIQFLRAQYEGLKRQQRTQAHLLVLPKGGNTPAPAESMVNAVWINKERRSSLSLEEADSEVEGRLEEAAQGCLQAPKSPWHTHLEMHCLVQTSPQDTSHQVHHRGKLVGSDQRLPPEGDTHLFETNQMTQQGTGIPEAAQLPCQVGNTQTKAVESGLKFSTQCPLSIKNPHRSGKPAYYPFPQRKTPRISQAARNLGLYGSA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**.*******:* :* : *******:**.*:***:.*********************:*:** * ***** *..:************ **:***.** **** :.* *** ***:**:* **** ::.** : :* ** .: **.*****.::::.* *:* *.*.** * ..: :.. * *:* * ** *******:*******.**************..", "identical_positions": 147, "similar_positions": 49, "identity": "61.0%" }, { "cls_id": "homologset.agr.HGNC:31456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A951-1", "uniprot_id": "D4A951_RAT", "id": "D4A951-1", "name": "", "aln": "MSSTRHHTWTRGSIGSLYLHRCSLPELYASLEIFNKESKKSNLQKICGMSFKEAQEVLWKILGGLISDSYDTVKGDERHPSIPVNKEERKTPSMSDLLHQSLLKGYNVPLEQVHSSQQRLAQVGIPPPPLSFPHGLSNELPVILPAQHFRKRIQSVTFRKLLLSSVAPGRLFYEEKPTSQQVSFDPGKQFLDLADLQWRYFKGLAKWGKMPRRFSLLNIEYNSEKRYVENQRMSGLIFPPLVRKTLMVYPQAEYDKEGQLYLTWKIVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TBE3-1", "uniprot_id": "CI153_HUMAN", "id": "Q5TBE3-1", "name": "Uncharacterized protein C9orf153", "aln": "MFLTGDTSPAEDNR-EATLPQCSLPELYACIENFNKESKKSNLLKMHGISLNEAQEVLARNLNVMSFTRGADVRG-DLQPVISVNKMNK-------------------PGKHRKTPSPKINK--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . : :... . * :********.:* ********** *: *:*::****** : *. : *:* : :* *.*** :: * :: ::.. :: : ", "identical_positions": 40, "similar_positions": 32, "identity": "14.93%" }, { "cls_id": "homologset.agr.HGNC:3146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42892-1", "uniprot_id": "ECE1_HUMAN", "id": "P42892-1", "name": "Endothelin-converting enzyme 1", "aln": "MRGVWPPPVSALLSALGMSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAALG---------------IQYQTRSPS----VCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN---------STASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIERLGGWNITGP------WAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENE-KVLTGYLN-YMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLEQISTLINTTDRC-----LLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT-----------ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNS-SVEAFKRQTECMVEQYSNYSVNGEP--VNGRHTLGENIADNGGLKAAYRAYQNWVK--------KNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESS--------HEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNP-PHKCEVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4PZA2-1", "uniprot_id": "ECE1_MOUSE", "id": "Q4PZA2-1", "name": "Endothelin-converting enzyme 1", "aln": "MRTVWSP-LAAALAALGMSTYKRATLDEEDLVDSLSEGDVYPNGLQVNFRSSRSGQRCWAARTSVEKRLVVLVTLLAAGLVACLAALG---------------IQYQTRTPP----VCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAVIKHLLEN---------ATASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIEKLGGWNITGP------WAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENE-KVLTGYLN-YMVQLGKLLGGGDEDAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLRQVSTLINNTDKC-----LLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCIPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIIMEIKKAFEESLSTLKWMDEETRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT-----------ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNS-SVEAFKQQTECMVQQYSNYSVNGEP--VNGRHTLGENIADNGGLKAAYRAYQNWVK--------KNGAEQTLPTLGLTSNQLFFLGFAQVWCSVRTPESS--------HEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNP-HHKCEVW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42893-1", "uniprot_id": "ECE1_RAT", "id": "P42893-1", "name": "Endothelin-converting enzyme 1", "aln": "MGSLRPP----QGLGLQWSSFFLGKKGP-GLTVSLP---LLASSLQVNFRSPRSGQRCWAARTSVEKRLVVLVTLLAAGLVACLAALG---------------IQYRTRTPP----VCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN---------STASASEAEKKAQVYYRACMN-ETRIEELRAKPLMELIEKLGGWNITGP------WAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENE-KVLTGYLN-YMVQLGKLLGGGDEDSIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNAIFYPV--EINESEPIVVYDKEYLRQVSTLINSTDKC-----LLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILEIKKAFEESLSTLKWMDEDTRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSLRVT-----------ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNS-SVEAFKQQTECMVQQYNNYSVNGEP--VNGRHTLGENIADNGGLKAAYRAYQNWVK--------KNGAEQILPTLGLTSNQLFFLGFAQVWCSVRTPESS--------HEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNP-RHKCEVW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1NC81-1", "uniprot_id": "A0A8M1NC81_DANRE", "id": "A0A8M1NC81-1", "name": "Endothelin-converting enzyme 1", "aln": "MESLRES---ILHLTFQMSTYKRATLEEEELLDTGSDGIYHTSSMQVGVQRG-LGLRCWAEKTHSERKLVVLVCALSVALFICIMSLG---------------LHYKESHPG----LCLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENT--------SMKSLSRAEQKAQWYYQACMN-ESKIEELGAKPLQDLINQTGGWGLKGP------WEKDNFQEVLRIVSANFRTSPFFTVFVSTDSKSSNSNIIQVDQSGLGLPSREYYLNKTANE-KYLNAYLN-FLVELGVLLGG-SQDTSQKMMEEIIEFETTLANITVPQVERRDEEKIYYKIQAKELATLAPAIDWMPFLSSVFAPV--ELNDSEPVVVYAKEYLQKVSELISNTNKS-----VLNNYMIMKVVRKMVSILDQKFQDAEQRFLEVMYGTKKSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVT-----------ADQLRKAPNRDQWSMTPPTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLAKWWQNS-SVEAFQHQTQCMVEQYSNYSINNEP--LNGKHTLGENIADNGGLNAAYKAYVNWIK--------KNGEEASLPALGMNNHQLFFVGFAQVWCSVRTPESS--------HEGVITDPHSPSRFRVIGTISNSHEFSEHFGCKADSPMNP-KRKCELW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5Y0-1", "uniprot_id": "NEP3_DROME", "id": "Q9W5Y0-1", "name": "Neprilysin-3", "aln": "MTRYKQT---------EFTEDDSSSIGGIQLNEATG-----HTGMQIRYHTARATWN-WRSRNKTEKWLLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKP--------AKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSG---YNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIE-YMTKVCVLLGANESDAR-AQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDG-GEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSN-----------LKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSK-SIERFNEKSECIARQYSGYKMNGRT--LNGKQTLGENIADNGGLKAAYHAYQRTKSD-------RDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETN--------LLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNP-TEKCEVW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK72-1", "uniprot_id": "Q9VK72_DROME", "id": "Q9VK72-1", "name": "", "aln": "-----------------------------------------------------MVNALWATLIS----LTLIGRVLANDLFSLPPATN-----------------------------HREEMLEDYGRFLLSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTTSAEIKAKQFYASCVEMKANLSLG-----YQYFMEHDGDRLKER--------NATYDWMYINFMSKYDIYPLLALKVHYSTSSRKFDILLT------LPS------------KVLAGFSEEQLKNMTREFGLDSSAEKVKQFVENFNNLTQFERNLVSLAKSRNETEQLN-FKEFLVKHKHDRLNWTRFFELAFNGS----QESHWPVLNQLDNINDLVFFLEQTNLE-----TLKGYIKMRELVKFYGLWKTQTKTG----------------GVQSECRSLSETYFNYALLPWFIGKVFDKERRADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDDLQHREVIDGVYSDINMTGN-WFENLCILEGSRARIR-----------LRSVDKALIP--LLMPTRTVNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWWSSA-SLRNFKERYRCLESQYNKFILMGVQ--TNGSLTSGDNIADNVGTRMAYYAFKRKTGD-------KAWLEKPLRGVNFNNKQLFFVKFAQTWCNGKDNGDK--------LRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEMNP-LKKCVVW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH96-1", "uniprot_id": "Q9VH96_DROME", "id": "Q9VH96-1", "name": "", "aln": "------------------------------------------------------MFHESLKLISLMLLWVIVAAVLTDCEARSLVDRS----------------ENSDSNGSSTNRSAAEYQLQEYAEFMKSYMNQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMD-----LAEALNVSSELAVAQRFYNACLGANLHPFNAADPAYLSLIRSIGGFPAVDG--------------------DAWKASNFNWINMSAHLANYGANGLIRETLQLRYPFEPYTKLPELGFDHIIVHEEN-ISRNTTRAFRLNEERMHGYLRAFGLPEDRIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRVFPQSEYYYNISWSG-----LHSTNKLFCDFYYVELDKVCARHRKA------VANYLAMKLLYRFDPKLKAPRYQR-------------------NYCSVTLYQSMRFLFNKLYMANNFSEAKRLEMSEMVRELRKSLRKALEDADWLDAESRARALLKESRIQPRIGSFQDDALSDRIIREINSLKVIEDRYAETNINLQHLVVQINRFSSRH-----FQELTNDTKPQKILTGLQVGAGYYTP-DNSINVMAGVVEPPIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEI-SQQALEDRAECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQL-LEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCSHYEEEHY--------WKGLS-DVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGAKTCRLW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCU2-1", "uniprot_id": "Q9VCU2_DROME", "id": "Q9VCU2-1", "name": "", "aln": "-----------------------------------------------------MSDPCWTTVFLWLLWLPHLQQNALVSGEDLPPPFQR-------------------------IYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYACGNWKS-TLTPQQQLQQQTDRELLLLVEEAVR----------------REDSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGMDILIGLRVGYNYGNVNENSLYLSEPSTLIPTELCTRNRSDIR-DSIYEPLEHRVASELKSWLALGHDESARLAADILSFEHELCGGMKGGSFESWDAEEQLYLANYTRKTLREFSNSIELDLDSYVRASFGQDIYKPVYMAAPEYFRQLKRTVSAHNIS-----LVANYIMYRAVSALNFPLDDRPQLR------------------KRECLERTKELLPTALGELYARQFGTEDGRIDLDNLYDTLKTALRQSLG-AEWLVEGTQRVGQEKLRNLK--------LQMPTYERPVILKLQLERGNYWQNLRQLLGVVQSQR-----N-----NRLFEEFLPAPTDPVEAYEARVRLRPVQRRLDMGLALLQPPAYDPRYGHAIRYATLGVQLAQQLVMAFDDP--HWSVGLLERDNWDGQ-TAWQYHIRSNCFARQVDNYLRPNVS-------ATTQLITDSAAINVAFRAYLTWLGFQEPNNDFTKLTKETLPDLNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNP-ASKCIIY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VME3-1", "uniprot_id": "Q9VME3_DROME", "id": "Q9VME3-1", "name": "", "aln": "-----------------------------------------------------------MLKLSLVAWLIFSLAWRTTPTACRQTNAP-------------------------------QSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLG-------LIDHSVNRKLELLLRRRNESSFESDSSILEQMR-LYYRSCKRLKPYNLKKYLQ----LLPPSNSTQWPSVGRGWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWDDSRNYSIYVNK----PSRQETQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRLQELEDDEGPREMQLGYLDSYLPQLRWLSFMRQVRIDS--ELDLRSTLIIENIPYLRALSDLMESESPD-----TVCSYIMLKWLAFLKQQGPADISRG--------------------ECVAALRRAMPLASSWLVGQQFSDPESESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRAVRLQMGFFQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVEEIGASRQFRQGLQCLQQQMAT-----------GSKWIDEKLADFVALRLAYETFFGVRDK-------REPRDPLLP--QFSQRQLFFITFAQFFCGRTPVLSPR-------SQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQA-SQRCRIW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . ** :*: ::*. : : :.. . : : . : : : : : : .*: . : * . . .: :: : * . : : . . . . .: : * : ... :* :.::: .** :. . : . .* : ::* . . * :: : . ***: :** *. *: .: * : * :* : * *.. * ::", "identical_positions": 27, "similar_positions": 84, "identity": "3.2%" }, { "cls_id": "homologset.agr.HGNC:3147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMI0-1", "uniprot_id": "ECEL1_MOUSE", "id": "Q9JMI0-1", "name": "Endothelin-converting enzyme-like 1", "aln": "--------------------------MEAPYSMTAHYDEFQEVKYVSRCGTGGARGTSLPPGFPRGSGRSASGSRSGLPRWNRREVCLLSGL---VFAAGLCAILAAMLALKYLGPGAAGGGGACPEGCPERKAFARAARFLSAN--LDASIDPCQDFYSFACGGWLR--RHAIPDD-KLTYGTIAAIGEQNEERLRRLLARP---TGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGG--------WDLGG----AADRPG-AARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLP--------------ERTLYLAQDEESE-----------------------------KILAAYRVFMQRLLR----LLGADAVEQK----AQEILQLEQRLANISVSEYDDLRRDVSSAYNKVTLGQLQKIIPHLQWKWLLDQIFQEDFSEEEEVVLLAT-----------DYMQQVSQLIRSTPRR--ILHNYLVWRVVVVLSEHLSSPFREALHELAKEMEGNDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEE---LDWMDAQTKAAARAKLQYMMVMVGYPDFLLKPEAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSSWLLPPQALNAYYLPNKNQMVFPAGILQPT-LYDPDFPQSLNYG----GIGTIIGHELTHGYDDWGGQYDRSGNLLH-WWTETSYSHFLRKAECIVRLYDNFTVYN--QRVNGKHTLGENIADMGGLKLAYYAYQKWVR-----EHGPEHPLHR----LKYTHNQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNP-VHKCSVW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHL3-1", "uniprot_id": "ECEL1_RAT", "id": "Q9JHL3-1", "name": "Endothelin-converting enzyme-like 1", "aln": "--------------------------MEAPYSMTAHYDEFQEVKYESRCGTGGARGTSLPPGFPRSSGRSASGARSGLPRWNRREVCLLSGL---VFAAGLCAILAAMLALKYLGPGAAGTGGACPEGCPERKAFARAARFLSAN--LDASIDPCQDFYSFACGGWLR--RHAIPDD-KLTYGTIAAIGEQNEERLRRLLARP---TGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGG--------WDLGG----AADRPG-AARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLP--------------ERTLYLAQDEGSE-----------------------------KVLAAYKVFMERLLR----LLGADAVEQK----AQEILQLEQRLANISVSEYDDLRRDVSSVYNKVTLGQLQKITPHLQWKWLLDQIFQEDFSEEEEVVLLAT-----------DYMQQVSQLIRSTPRR--ILHNYLVWRVVVVLSEHLSPPFREALHELAKEMEGNDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEE---LDWMDAQTKAAARAKLQYMMVMVGYPDFLLKPEAVDKEYE-FEVHEKTYLKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPT-LYDPDFPQSLNYG----GIGTIIGHELTHGYDDWGGQYDRSGNLLH-WWTEASYSRFLHKAECIVRLYDNFTVYN--QRVNGKHTLGENIADMGGLKLAYYAYQKWVR-----EHGPEHPLHR----LKYTHNQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNP-VHKCSVW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95672-1", "uniprot_id": "ECEL1_HUMAN", "id": "O95672-1", "name": "Endothelin-converting enzyme-like 1", "aln": "--------------------------MEPPYSLTAHYDEFQEVKYVSRCGAGGARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGL---VFAAGLCAILAAMLALKYLGPVAAG-GGACPEGCPERKAFARAARFLAAN--LDASIDPCQDFYSFACGGWLR--RHAIPDD-KLTYGTIAAIGEQNEERLRRLLARP---GGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGG--------WDLGG----AEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLP--------------ERTLYLAQDEDSE-----------------------------KILAAYRVFMERVLS----LLGADAVEQK----AQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEEEEVVLLAT-----------DYMQQVSQLIRSTPHR--VLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEE---LDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPT-LYDPDFPQSLNYG----GIGTIIGHELTHGYDDWGGQYDRSGNLLH-WWTEASYSRFLRKAECIVRLYDNFTVYN--QRVNGKHTLGENIADMGGLKLAYHAYQKWVR-----EHGPEHPLPR----LKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNP-AHKCSVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMQ2-1", "uniprot_id": "Q8IMQ2_DROME", "id": "Q8IMQ2-1", "name": "", "aln": "MTMEDRNRIWTTGNINHGFFGDNLQQQPLPLQRLQTPGNLSLLSAPIRANGSGNGNATANGHGQNSATESANGKQLPYEPISPNLIGIQSKFRRSYYHKVVLGGLLALVIILLIAIIVISLGLKKSSSICRSKECLRTAASLIYA--MDEQTDPCEDFYQFTCGRWAN--EHPRPDS-VTSNDWFRERQAHIMRVVREFLRSN---ITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENMTKPSKNPADDIVYITLQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPAS--HIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKS---TSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNEMDKPEPIG-WATSPSNVNAFHTFQSNAITVPIAILQYP-FYDLGL-EALNYG----SIGTILGHELTHGFDDSGRRFDRAGNMVE-WWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVK-----EVGRERSKLPGL--EHYSHEQLFFISFGNLWCETYTP-AASRYALTDSHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAS0-1", "uniprot_id": "Q9VAS0_DROME", "id": "Q9VAS0-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MTMKLFCIWIASHVLSVLVLAAPTSEDVLNQDTPYMKELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYKR--INSALNMRVLTTGVFETLTKGLNRKILKMLNTP---HDSHDTPEDIQVKHFYESCLQIKELNSTYSEKLKRLIAEFGT--------MPLLE----GSSWQEDDFDWLNTTARMAHRYGIMSIIGVGVATDFANNQKN--IIYINQQEFPLK--------------TRSMYMDNETAIYR---------------------------QNYQNNIQLILEKYLG------VKDELARK---AAKEMFEFEVDLAHGLVDNNKHLN-----LRDLIELLTVAELRERYAPTLDTDQLIFVSMGEKISDKVYEYN---------RRYQQNLVEVIERTPKS--TVANYLFLRLIWEFIQKPSG-----------------VAEKPTEACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAMTLEVNN----YVKENFTEEFADLNLQNTDCVENLR-QVQMLQAKQMRQLYHQPAKPLEAGELLSYTPSNILLENSIKVPVALLQPFYIWSDVYPNAVMFG----TLAYLIGHELIHGFDDSGRKFDEKGNSKD-WWDEKSSSNFLKRRDCFTKQYGRYVYDG--IQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDVHPKVKALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNP-IEKCILY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYJ1-1", "uniprot_id": "Q9VYJ1_DROME", "id": "Q9VYJ1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MKPPLSSITRLVVILGVMLLKLAAAQDCQQQLDNDT----------------DAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPL-----------------LANHTGGSFDWVLANAALR---TYGAQGLWRLLVKDNWQSADQRIFYMLPPKFDLLG--------------------RDDELN----------------------------EFLYQRYLKILLLELG---------LRVRRAALLAEKLVAFEKSLQKLLPNDAEQTL----VLRKPQSLKDLESQLPRLELKRYFETILEGIDWDSKTLLLVAD----------LDYLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFELRLHDDDKLGNQR--------NHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTAIQQIAVLFRDLKQQFELVLNET-EVFNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTPQLG------GNCDANLLQLSLSQAKLEYRQVFG-EPVTSVPADPLSVNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGCYLGVR----------YSNATLTVNENIADTEGLRLALDTYRHRSG---------------------ATNLRTFFVAFAQNWCG-----TVASTSGLSQHAGHAERVNNVVGNMPEFGDTFECKATSQMNP-VNKCHIW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : . .**::*: ::** : : . . . : . : ::..*: : . . * : . . . : : .. : : :: *.:: .: : . . . . : : * * : . : . : .:*. : : : : :: : ::: : : . : *: : * * *: . .:: .. * : .* .:: : . :: . :. ::.**: *.:* * .:* *: . * : .: : * . : .***** *:: * :*: : : **::*.: ** ..* *: . :.: **. *.* : *** ** ::", "identical_positions": 50, "similar_positions": 134, "identity": "5.49%" }, { "cls_id": "homologset.agr.HGNC:3148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVR2-1", "uniprot_id": "TYPH_RAT", "id": "Q5FVR2-1", "name": "Thymidine phosphorylase", "aln": "MAAPGTPPPLAPETAGADSGGGSG-------EHRQLPELIRLKRNGGHLSEADIRNFVHALMDGRAQDTQIGAMLMAIRLQGMDLEETSVLTQALAESGQQLEWPKAWHQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRSLGHTGGTLDKLESIPGFSVTQSPEQMLQILEEVGCCIVGQSEKLVPADGILYAARDVTATVDSVPLITASILSKKAVEGLSTLVVDVKFGGAAVFPDQEKARELAKMLVRVGMGLGLQVAAALTAMDNPLGRNVGHTLEVEEALLCLDGAGPPDLRDLVIRLGGAILWLSGQAETQDQGAARVAAALDDGSALHRFQLMLSAQGVDPGLARALCSGSPTQRRQLLPHARKQEELLSPADGIVECVRALPLACVLHELGAGRSRAGQPIRPGVGAELLVDVGQWLSRGTPWLRVHLDGPALSSQQRRTLLGALVLSDRAPFKAPSPFAELVLPPTTP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N42-1", "uniprot_id": "TYPH_MOUSE", "id": "Q99N42-1", "name": "Thymidine phosphorylase", "aln": "MAAPGTPPPSA-------SGGGGG-------EPRQLPELIRLKRDGGHLREADIRNFVHAVIDGRAQDTQIGAMLMAIRLQGMNLEETSVLTRALAESGQQLEWPKAWHQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRSLGHTGGTLDKLESIPGFGVTQSPEQMLHILEEVGCCIVGQSAKLVPADGILYAARDVTATVDSVPLITASILSKKAVEGLSTLVVDVKFGGAAVFPDQEKARELAKMLVRVGVSLGLKVAAALTAMDNPLGRSVGHTLEVEEALLCLDGAGPPDLRDLVIRLGGAILWISGQAETQDQGAARVAAALDDGSARRRFQLMLSAQGVDPGLAKALCSGSPTQRRQLLPHAREQEELLAPADGIVECVRALPLARVLHDLGAGRSRAGQPIRPGVGAEVLVDVGQCLSRGTPWLRVHLDGPALSSQQRRTLQGALVLSDRAPFKVPSPFAELVLPPTIAQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19971-1", "uniprot_id": "TYPH_HUMAN", "id": "P19971-1", "name": "Thymidine phosphorylase", "aln": "MAALMTPGTGAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8W2-1", "uniprot_id": "A0A8M3B8W2_DANRE", "id": "A0A8M3B8W2-1", "name": "Thymidine phosphorylase", "aln": "MSSED--------------------------DTISFPELIKLKRNGGQLSLAEIHTFVQGVTTGAIQKSQIGAMLMAIWQKGMTDEETLALTREMMNSGDTFKWPNEW--LVLDKHSTGGVGDKVSLPLAPALAACGCKVPMISGRGLAHTGGTLDKLESIPGFNVNQSVQQVKQILEDVGCCIVGQTESLVPADRVLYAIRDATSTVDSLPLITSSIISKKGAEGLSALVLDVKFGRAALYKDLDRARSLAQCLVTAGNELGIKTGAVLSRMDAPIGQTVGNAVEVCEALECLKGRGPDDLRELVTNLGGHLLWMCGHSSTLENGKHEIAVKLKNGEALNKFQAMLEAQGVTADVARSLCSDE-SRYFEYMKRAANQTELKVPKDGAVLDIDGLALAEVLHKLGAGRTKSGEKIDHSVGAEMLVEMGQLVQKGQTWIRIHHSSVDLSAQQRSDLQKALVIGRQDQYKAASRIVEFIYPNHHMS-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : .:****::**:**:* *:*: ** .: * * :********* :** *** .**: : :**: ::**: * ::************** ******************.*.***************.* ** :*: :*::.*******: .***** :*** **.*:****:****:**:*** .****:**:***** **:: : ::**.**: ** .* **::..*.*: ** *:*: **:::** *** *:.* ** ***:** *** :**:.*:: * :* .:*. *.:*.* :*: ** **** ..:*::***.. :. : : :* :* ** * ** * : .*.** ***.*****:::*: : .****:**::** : :* .*:*:* .. **. * * ***:. : : ..* :.*:: * ", "identical_positions": 230, "similar_positions": 125, "identity": "47.42%" }, { "cls_id": "homologset.agr.HGNC:3149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62651-1", "uniprot_id": "ECH1_RAT", "id": "Q62651-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "MATAMTVSSKLLGLLMQQLRGTRQLYFNVSLRSLSSSAQEASK-RIPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASD-ILQPPGDDVARIAWYLRDLISRYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLISACDIRYCTQDAFFQVKEVDVGLAADVGTLQRLPKVIGNRSLVNELTFTARKMMADEALDSGLVSRVFPDKDVMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKKDSKSITFSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35459-1", "uniprot_id": "ECH1_MOUSE", "id": "O35459-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "MATAMTVSSKLRGLLMQQLRGTSQLYFNISLRSLSSSAQEASK-RAPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASE-LMQPSGDDAARIAWYLRDLISKYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLVSACDIRYCTQDAFFQIKEVDMGLAADVGTLQRLPKVIGNQSLVNELTFSARKMMADEALDSGLVSRVFQDKDAMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKRDTKSITFSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13011-1", "uniprot_id": "ECH1_HUMAN", "id": "Q13011-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "MAAGIVASRRLRDLLTRRLTGSNYPGLSISLRLTGSSAQEEASGVALGEAPDHSYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASD-ILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQDLVKSVQATTENKELKTVTFSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W5W8-1", "uniprot_id": "Q9W5W8_DROME", "id": "Q9W5W8-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "----MSLS-RLNTLMKLTPKPT----------AIGSLKMQRNLSALPESGPTGSFKTLAVSSPKPFVFHVELHRPSKFNAISKQMWLEIKECFDGLATNPDCRAIVLSASGKHFTAGIDLNDMINVGQTLAETDDYARKGVSMERMIKVYQDSISSLEHCPKPVITAVHKACIGAGVDLITAADIRYCTEDAFFQVKEVDIGMAADVGTLQRLPKAVGSQSLARELCFTGRKFEAAEAHSSGLVSRLFPDKDSLLTGALAVAELIASKSPVAVKTTKESLVYSLEHTNQEGLDHILLLNKLNLLSEDFAQAVAAQLTKDDKP--VFAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* *: : .* : . . .:::: *:*.: .*:**:*:**.* **:.: :* *: ***: :: :.****:*:*.:** **:**** ** . . ** ** . :. :*. **.::. :*:******:*:* .***.****::*.*****::*****:****:*:************.:*.:**..** *:.**: * ** .******:* **: :* .*:*:* *:*******: :* .*:** :*: *.*::: * * ::*: ::* * : : .*:**", "identical_positions": 134, "similar_positions": 97, "identity": "40.73%" }, { "cls_id": "homologset.agr.HGNC:315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JZQ2-1", "uniprot_id": "AFG32_MOUSE", "id": "Q8JZQ2-1", "name": "Mitochondrial inner membrane m-AAA protease component AFG3L2", "aln": "MAHRCLLLWSRGGCR-RGLPPLLVPRGCLGPDRRPCLRTLYQYATVQTASSRRSLLRD---------VIAAYQRFCSRPPKGFEKYFPNGKNGKKASEPKEAVGEKKEPQPSGPQ-PSGGAGGGGGKRRGKKEDSHWWSRFQKGDFPWD-------------------------------DKDFRMYFLWTALFWGGVMIYFVFK--SSGREITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTPG----KTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRG----PAGIGRTGRGMGGLFSVGETTAKVLKDEIDVK--FKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRG-NFGGQS-EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDS--ALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISDAYRRTVALLTEKKADVEKVALLLLEKEVLDKNDMVQLLGPRPFTEKS-TYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEEKKEKEKEEPLNEKVVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LN92-1", "uniprot_id": "F1LN92_RAT", "id": "F1LN92-1", "name": "", "aln": "MAHRCLLLWGRGGCR-RGLPPLLVPSGCLGPGRRPCLRTLYQYATVQTANSRSSLLRD---------VIAAYQRFCSRPPKGFEKYFPNGKNGKKASESKEAVGEKKESQLSGPQ-SSGGASGGGGKRRGKKEDSHWWSRFQKGDFPWD-------------------------------DKDFRMYFLWTALFWSGVMIYFLFK--SSGREITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTPG----KTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRG----PAGIGRTGRGMGGLFSVGETTAKVLKDEIDVK--FKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRG-NFGGQS-EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDS--ALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISEAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFTEKS-TYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEKKEKKEKEEPVNEKVVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4W6-1", "uniprot_id": "AFG32_HUMAN", "id": "Q9Y4W6-1", "name": "Mitochondrial inner membrane m-AAA protease component AFG3L2", "aln": "MAHRCLRLWGRGGCWPRGLQQLLVP-GGVGPGEQPCLRTLYRFVTTQARASRNSLLTD---------IIAAYQRFCSRPPKGFEKYFPNGKNGKKASEPKEVMGEKKESKPAATTRSSGGGGGGGGKRGGKKDDSHWWSRFQKGDIPWD-------------------------------DKDFRMFFLWTALFWGGVMFYLLLK--RSGREITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTPG----KTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRG----PAGIGRTGRGMGGLFSVGETTAKVLKDEIDVK--FKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRG-NFGGQS-EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDS--TLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKS-TYEEFVEGTGSLDEDTSLPEGLKDWNKERE------KEKEEPPGEKVAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39925-1", "uniprot_id": "AFG3_YEAST", "id": "P39925-1", "name": "Mitochondrial inner membrane m-AAA protease component YTA10", "aln": "-----MMMWQRYARGAPRSLTSLSFGKASRISTVKPVLRSRMPVHQRLQTLSGLATRN---------TIHRSTQIRSFH-ISWTRLNENRPN-------KEGEGKNNG----------NKDNNSNKEDGKDKRNEFG-SLSEYFRSKE--------------------------------FANTMFLTIGFTIIFTLLTPSSNNSGDDSNRVLTFQDFKTKYLEKGLVSKIYVVNKFLVEAELVN---------TKQVVSFTIGSVDIFEEQMDQIQDLLNIPPRDRIPIKYIERSSPFTFLFPFLPTIILLGGLYFITRKINSSPPNANGGGGGGLGGMFNVGKSRAKLFNKETDIKISFKNVAGCDEAKQEIMEFVHFLKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEMFVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALGGANDEREATLNQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDPLLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERVIAGLEKKTRVLSKEEKRSVAYHEAGHAVCGWFLKYADPLLKVSIIPRGQGALGYAQYLPPDQYLISEEQFRHRMIMALGGRVSEELHFPSVTSGAHDDFKKVTQMANAMVTSLGMSPKIGYLSFD-QNDGNFKVNKPFSNKTARTIDLEVKSIVDDAHRACTELLTKNLDKVDLVAKELLRKEAITREDMIRLLGPRPFKERNEAFEKYLD---------------PKSNTEPP---------EAPAATN---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40341-1", "uniprot_id": "YTA12_YEAST", "id": "P40341-1", "name": "Mitochondrial inner membrane m-AAA protease component YTA12", "aln": "---MLLLSWSRIATKVVR--RPVRFRSYYGLTHIKSLHTQYRLLNRLQENKSGNKNEDNNEDAKLNKEIPTDEEVEAIR-KQVEKYIEQTKNNTIPANWKEQKRKIDESIRRLEDAVLKQESNRIQEERKEKEEENGPSKAKSNRTKEQGYFEGNNSRNIPPPPPPPPPKPPLNDPSNPVSKNVNLFQIGLTFFLLSFLLDLLNSLEEQS-EITWQDFREKLLAKGYVAKLIVVNKSMVKVMLNDNGKNQADNYGRNFYYFTIGSIDSFEHKLQKAQDELDIDKDFRIPVLYVQEGNWAKAMFQILPTVLMIAGIIWLTRRS-------AQAAGGSRGGIFGLSRSKAKKFNTETDVKIKFKDVAGCDEAKEEIMEFVSFLKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFYFVSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDEIDAIGKARQKG-NFSGANDERENTLNQMLVEMDGFTPADHVVVLAGTNRPDILDKALLRPGRFDRHINIDKPELEGRKAIFAVHLHHLKLA----GEIFDLKNRLAALTPGFSGADIANVCNEAALIAARSDEDAVKLNHFEQAIERVIGGVERKSKLLSPEEKKVVAYHEAGHAVCGWYLKYADPLLKVSIIPRGQGALGYAQYLPGDIFLLTEQQLKDRMTMSLGGRVSEELHFPSVTSGASDDFKKVTSMATAMVTELGMSDKIGWVNYQ-KRD-DSDLTKPFSDETGDIIDSEVYRIVQECHDRCTKLLKEKAEDVEKIAQVLLKKEVLTREDMIDLLGKRPFPERNDAFDKYLNDY-----ETEKIRKEEEKNEKRN---------EPKPSTN---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * . : : : * .. : : : * ** : . .. : .* :. * : : : : ::: . . .. :*::** : * ** * :: **** :*.. : : *.***:* **.::: *: *.* *:*: *: ... . :: :***::::. : : *: * . **:*.:..: ** :: * *:* **:****:*** ****** ***:* :* .:*****:****:******************.*** ******:*******.:****** **. **.*:*******:*: * :* :.* . *:* ****:*******..: :**:********:** **:*******:* *. *:::** *: ***: *:* : .* :**:*****:***:**.********** . :. :**********.*:*:*:::*. ***: **********.**:*::*************:* ******** : :* :::*: .** *:********:.* :*:** **::***. * * :..:**. *:* :.:: .: : : **:*: *. ** ** ::.:.: . **.:: .*: :* **.**.: ::**: *** *** *:. ::::::: . * : * : ", "identical_positions": 306, "similar_positions": 201, "identity": "35.46%" }, { "cls_id": "homologset.agr.HGNC:3151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH95-1", "uniprot_id": "ECHM_MOUSE", "id": "Q8BH95-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MAAL-RALLPRACSSLLSSVRCPELRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEQDPAVGAIVLTGGDKAFAAGADIKEMQNRTFQDCYSSKFLSHWDHITRVKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVEKLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGNKLEKRLFYSTFATDDRREGMTAFVEKRKANFKDH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14604-1", "uniprot_id": "ECHM_RAT", "id": "P14604-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MAAL-RALLPRACNSLLSPVRCPEFRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANFKDH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30084-1", "uniprot_id": "ECHM_HUMAN", "id": "P30084-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MAAL-RVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZZ04-1", "uniprot_id": "Q7ZZ04_DANRE", "id": "Q7ZZ04-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MALLCRSTGLLLKHSKLLPSALAATRQSSSGVQYEYILVDKKGEKKNVGFIQLNRPKALNALCDGLMLEVGKALDAFEMDSEVGAIVVTGSEKAFAAGADIKEMQNRTFQECYGGNFLAHWNRVSTVKKPVIAAVNGFALGGGCEFAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQEAKQSGLVSKIFPVDQLVPEAIKCGEKIAGNSKLVSAMAKESVNAAFELTLAEGSRFEKRLFHATFATEDRKEGMSAFVEKRKAAFQDK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * * . . . * :**.:::**:.:*:*::..**:*************:**: *:.:**.:** *. *****:**.:************** :**:**..:** **:::: :**********:*:*****:***************.*****:**********************************:***:****** **: ** ***:*.****.***:: ************:**:**.::**:**::****:**:***:******** *:*:", "identical_positions": 196, "similar_positions": 64, "identity": "67.35%" }, { "cls_id": "homologset.agr.HGNC:3153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61508-1", "uniprot_id": "ECM1_MOUSE", "id": "Q61508-1", "name": "Extracellular matrix protein 1", "aln": "MGTVSRAALILACLALASAASEGAFKASDQREMTPERLFQHLHEVGYAAPPSPPQTRRLRVDHSVTSLHDPPLFEEQREVQPPSSPEDIPVYEEDWPTFLNPNVDKAGPAVPQEAIPLQKEQPPPQVHIEQKEIDPPAQPQEEIVQ---KEVKPHTLAGQLPPEPRTWNPARHCQQGR-RGVWGHRLDGFPPGRPSPDNLKQICLPERQHVIYGPWNLPQTGYSHLSRQGETLNVLETGYSRCCR---CRSDTNRLDCLKLVWEDAMTQFCEAEFSVKTRPHLCCRLRGEERFSCFQKEAPRPDYLL--------------------------RPCPVHQNGMSSGPQLPFPPGLPTPDNVKNICLLRRFRA--VPRNLPAT--DAIQRQLQALTRLETEFQRCCRQGH-NHTCTWKAWEGTLDGYCERELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDILTLDLSRVTPNLMGQLCGSGRVLSKHKQIPGLIQNMTIRCCELPYPEQACCGEEEKLAFIENLCGPRRNSWKDPALCCDLSPEDKQINCFNTNYLRNVALVAGDTGNATGLGEQGPTRGTDANPAPGSKEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62894-1", "uniprot_id": "ECM1_RAT", "id": "Q62894-1", "name": "Extracellular matrix protein 1", "aln": "MGTIRSSALILACLALASAASEGAFKVSDQREMKPEHLFQHLHEVGYAAPPSPPQTRRLQVHHSETSPHDPPLFEEQKEVQPPSSPEDIPVYEEEWLTFLNPNVGKVDPALPQEAIPLQKEQPPPRIPIEQKEIDPPVQHQEEIVQSRQKEEKPPTLTGQHPPEPRTWNPARHCQQGR-RGIWGHRLDGFPPGRPSPDNLKQICLPERQHVVYGPWNLPQTGYSHLSRQGEALNLLETGYSRCCR---CRSDTNRLDCVKLVWEDAMTQFCEAEFSVKTRPHLCCKQRGEERFSCFQKEAPRPDYLL--------------------------RPCPIHQTGISSGTQLPFPPGLPTPDNVKNICLLRRFRS--VPRNLPAT--DAIQRQLQALTRLETEFQRCCRQGH-NHTCTWKAWEDTLDGYCDRELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDLLTVDLSRVTPNLMDHLCGNGRVLSKHKQIPGLIQNMTVRCCELPYPEQACCGEEEKLAFIEDLCGPRRNSWKDPALCCTLSPGDKQANCFNTNYLRNVALVAGDTGNATGLGQQGPTGGTNVGPAPGSKEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16610-1", "uniprot_id": "ECM1_HUMAN", "id": "Q16610-1", "name": "Extracellular matrix protein 1", "aln": "MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPE----HFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPP-FEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQK------------------EGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCH---CRSHTNRLECAKLVWEEAMSRFCEAEFSVKTRPHWCCTRQGEARFSCFQEEAPQPHYQL--------------------------RACPSHQPDISSGLELPFPPGVPTLDNIKNICHLRRFRS--VPRNLPAT--DPLQRELLALIQLEREFQRCCRQGN-NHTCTWKAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IMZ6-1", "uniprot_id": "A0A0R4IMZ6_DANRE", "id": "A0A0R4IMZ6-1", "name": "", "aln": "--MVWKSTLLSAVILHLFSSGAG---------------------------------------------------------------------------------QNMDPDVLMDSI-------------------------------------------------------------------------FPPARPSLYNLNSLCLHGNGRFRYTAESFPPSSFAHARRAGKTMNRLEAWFGQCCYGGLAHKNGQILCCAKQAWETALSYFCLEEFSTKTLVHDCCEKKGGERWGCFEREAPNPYYQP--------------------------LPG-YIAPQISSDRIFTWDP---------KAC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7D9-1", "uniprot_id": "A0ACD6B7D9_DANRE", "id": "A0ACD6B7D9-1", "name": "", "aln": "MSSPRGVGLYLTLLFALLCDASED-------------------------------SSLLQRDITDMLVDEVADGHQKESPLSPEEIEFLMMQRPVLPDFSKVMVAGSSDMTQREVTNFHPENVPIGPPVFGP---------------------------------------------RSAGPRTGPEVDFPPAFPNTGNLQDICRFSKAPVRYPKDMFPSSGFGNVARQGEAVNQLQSWYGVCCG--INGTQEEQICCAEQAWKKSLSAYCSQEFTIKTSHFFCCKKNGRARWSCFDKEASDSSYQVSSEISNGNASQKFKGFKYNSSACKGSLASPKALKKQTAAPDLTFPPGRPESSNIANICAHRKIRPRYITSCLPHTGYGWLVRQSKTINVLEREYNRCCKEKKGVQRCAEQKWKKMVDKFCKDEKKSKRQQFECCEKKKREEQYACFTSAAPDPGYSSTDGQLSSTAAPP-TLHTFCDVHTAIQSMKGFPFSLDNMAERCCLLAAQERPACIEAELGSHLNDMCKTKEPVKHH----CCASEIKNHVKCATKLLLRHIGKANKVKESGRKKCPLNI---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : . . . : ***. *. **:.:* . . * :* :.:.: * *:::* *: :. ** .. : : * : .*: ::: :* **: ** . ** .* *:.**:.**. . * . :: :.: * : * ", "identical_positions": 34, "similar_positions": 52, "identity": "5.7%" }, { "cls_id": "homologset.agr.HGNC:3154", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FW85-1", "uniprot_id": "ECM2_MOUSE", "id": "Q5FW85-1", "name": "Extracellular matrix protein 2", "aln": "MKLAVLFCFILLIVL---QTDCERGTRRQ--RRRMHQRRLRKSS-SFHLRANRQLEVQQTTA-APDARLPTANSDYSVEENIESLLSNLGVESSYSVLPGKKGYCFVKGMIMYNKAVWSPEPCTTCLCSNGRVLCDETECHPKACPYTIKPEGECCPICSDAEQESINK-----------------------LHKQVPPPQMEMDQVAIKEALQSEEDEEIAEGHKEHKKETSVPTKIHGDGERTERKLRPEKEGRSAHQPLYHGRREEEESKEETER------EGEEEEEEE----EEEEEDA----IRGDVFRMSSR-----------VIPGTPR----------------------GRPRLPRSCSLSYRTISCVHADFTEIPPITAPEVTNLELVGNSIISIPDEAFNGLPNLERLDLSRNNITSSGIGPKAFKSLKKLMRLNMDGNNLVHIPSDLPSTLEELKINDNNLQAIDEKSLSDLNQLVTLELEGNNLSEINVDPLAFQSLESLSYLRLGRNKFRIIPQGLPASTEELYLENNQIEEITEICFNHTRKITMIILRYNKIEESRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLIGNQIDRIPGYVFGHMQPGLEYLYLSFNRLSDDGVDLVSFYGAYHSLRELFLDHNDFKSIPPGIQDMKALHFLRLNNNKIRNIHPEQICNAEEDEDSALEHLHLENNYIRTREISSYAFSCIRLYSSIVLKPQHIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZS41-1", "uniprot_id": "D3ZS41_RAT", "id": "D3ZS41-1", "name": "", "aln": "MKQAVWFCLLLLILLTVFQTDCEPSPRRQ--RRRMHQR-LRKSS-SLYPRADRWLEVQQTTA-APDAGLPTAHSDYSVEENIQSLLGNLGVESSYGVLPGKKGHCSVKGMVMYNKAVWSPEPCTTCLCSNGRVLCDETTCPPKTCPYTVKPEGECCPICSDTEQ-----------------------------------------QESINQGRRKEEDS------------------------------------------------EEETEREGEEE------EEEEEEEEE----EEEEEDG----VRGDVFRMSSR-----------LIPGIPR----------------------GRPRLPRSCSLSYRTISCIYGDFTEIPPITAPEVTTLELVGNSIISIPNEAFNGLPNLERLDLSRNNITSSGIGPKAFKLLKKLMHLNMDGNNLVHIPSELPSTLEELKINDNNLQAIDEKSLSDLNQLVALELEGNNLSEINVNPLAFKSLKNLSYLRLGKNKFRIIPQGLPASIEELYLENNQIEEITEICFNHTRKITMIVLRYNKIEESRIAPLAWINHENLESIDLSYNKLYHVPSYLPKSLLHLVLIGNQIERIPGYVFGHMKPGLEYLYLSFNRLSDDGVDLVSFYGAYHSLRELFLDHNDFKSIPPGIQGMKALHFLRLNNNKIRNILPEQICNAEEDEDSALEHLHLENNYITTRAMSPYAFSCIRLYSSVVLKPQRIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94769-1", "uniprot_id": "ECM2_HUMAN", "id": "O94769-1", "name": "Extracellular matrix protein 2", "aln": "MKIAVLFCFFLLIIFQTDFGKNEEIPRKQ--RRKIYHRRLRKSSTSHKHRSNRQLGIQQTTVFTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEPCTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGDSSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEE------EEGEEGEED----EEDEEDP----VRGDMFRMPSRS----------PLPAPPR----------------------GTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIKIREIPSYTFSCIRSYSSIVLKPQNIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R2S9-1", "uniprot_id": "F1R2S9_DANRE", "id": "F1R2S9-1", "name": "", "aln": "MRPNLILAMSLLACLTFSLANEQRRPLVQGKRRGVGPKRARKQTSNISLQQGR----------TPES------NGQDRSVFMESYKKTKEPKPNFEVTAGKSENCVFRGITMYDQTAWSPKPCVSCLCSKGEVVCDQILCPTLQCQLKFQPMGECCPICIDQVLDEFSGDPPTPNDLADPYIEISHNRRDKDRLKKDEEERVRKKDAERKQRKKQKKEEAERQKKLKEAKEAKEKEAEQRRLREEEEEKAAAEERKKKMEEQRRAEEERARRLEMEQREMMRALEEAAERAQEGLRGDEATEDEDIVWLRGDVFQMSLVQPTKEASPSLLPLPEPSEPVEEDTETGEEGPDVFEEESEMVTTLLPPGCTISDVIVTCENAKLMGIPPLSIPELKSLNLQGNEIKTIPAGAFNGIPNLEWIDLGKNKIHSSGIDPQAFKGLKLLSRLYMDGNLLEQIPTELPSTLQELKINENNLREIEENSFEGLSSLVTLEMEGNLLSEGNVNPQAFKPLKELNYLRLNRNHFRTIPQGLPESLLELYLENNLIEDISEMAFNHTTNINVVVLRHNKLDESGIAPLAWINNRNLESIDLSYNNFYLVPSFLPKSLVHLVLVGNQIERIPGYVFAHMEPGLEYLYLSYNKLDGDGVEPESFFGTLNTMTELCLDHNHLMAIPMGINEMTTLHFLRLNNNKIRHVPEQAICDPLSEDDSHLVAVRLENNFIDPRKIPPTAFSCVRSYSSVVLKPQRIK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : :.: ** : . : . * ** : : **.: . : .* :* : . . . ::* :..: * .**. * .:*: **:::.***:**.:****.*.*:**: * . * .. * *****:* :: :.:::. .. * :. * * :: :* ** :***:*:*. :* .. ** .*::* ::* . : ***:: *::..*:* **.* :** ****:**** :**.:*:* ****.*:*** ** * :* **** * :**::*****:***:*:***: *:*:*:..*..**:**:*** *** **:* **:.*:.* ****.:*:** ****** * ******* **:*:*:.**** :*.:::**:**::*. ********:.**********::* ***:*****:****:****:*******.**:*********:*:* .**:: **:*: ::: ** ****.: :** **: *.:************:: : **:. .::** * ::****:* * :.. :***:* ***:*****.**", "identical_positions": 275, "similar_positions": 174, "identity": "36.81%" }, { "cls_id": "homologset.agr.HGNC:3155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUD0-1", "uniprot_id": "D3ZUD0_RAT", "id": "D3ZUD0-1", "name": "Protein ECT2", "aln": "MADDSVLPSPTEITSLADTSVFDSKVTETSKENLCMVSTSNVDEEMPQVEARVVVVQEAGKQEELLKALKTVKIMEVPVIKIKESCPGKSDEKLIKSIINMEIKVPCVKMDSMEEFGSLDSPEFENIFVVTDFQTSVFNDLYKADCRIVGPPVILNCAQMGEPLPFSCRPLYCTSMLNLVLCFTGFRKKEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSLGTPIMRPGWIYEAWERRNEQCFCAADDDFRNEFKVPPFQDCILSFLGFSDEEKHSMEEMTEMQGGTYLPVGDERCTHLIVDEN------------------------------------------------------------------------------TVKELPFEPSKKLFVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRR------------------------------------LKESLAQLSRETDLSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPDSSIHYGETPKSCAKSSRS-----------------------------------------------------------------------------------------------------------------------------------------STPVPPKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGDIFLKYSKDLVKTYPPFVNFFEMSKEMIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLIQRVETVSLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHDRTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSEELPKESWLKMLCRHVANTICKADAENLMYVTDPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRMALSSSH-SSEGRSPPSSGKLAVSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07139-1", "uniprot_id": "ECT2_MOUSE", "id": "Q07139-1", "name": "Protein ECT2", "aln": "MADDSVLPSPSEITSLADSSVFDSKVAEMSKENLCLASTSNVDEEMPQVEARVIMVQDAGKQEELLKALKTIKIMEVPVIKIKESCPGKSEEKLIKSIINMEMKVPCVKMDSMEEFESLDSPEFENIFVVTDFQNSVFNDLYKADCRIVGPPVILNCAQRGEPLPFSCRPLYCTSMLNLVLCFTGFRKKEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQCFCAAVDDFRNEFKVPPFQDCILSFLGFSDEEKHSMEEMTEMQGGSYLPVGDERCTHLIVEEN------------------------------------------------------------------------------TVKDLPFEPSKKLFVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRR------------------------------------LKETLAQLSRETDLSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPESSIHYGETPKSCAKSSRS-----------------------------------------------------------------------------------------------------------------------------------------STPVPPKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGDIFLKYAKDLVKTYPPFVNFFEMSKEMIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETVSLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHDRTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSEELPKESWLKMLCRHVANTICKADAENLMYVADPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRMALSSSH-SSEGRSPPSSGKLAVSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8V3-1", "uniprot_id": "ECT2_HUMAN", "id": "Q9H8V3-1", "name": "Protein ECT2", "aln": "MAENSVLTSTTGRTSLADSSIFDSKVTEISKENLLIGSTSYVEEEMPQIETRVILVQEAGKQEELIKALKTIKIMEVPVIKIKESCPGKSDEKLIKSVINMDIKVGFVKMESVEEFEGLDSPEFENVFVVTDFQDSVFNDLYKADCRVIGPPVVLNCSQKGEPLPFSCRPLYCTSMMNLVLCFTGFRKKEELVRLVTLVHHMGGVIRKDFNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQDFYAAVDDFRNEFKVPPFQDCILSFLGFSDEEKTNMEEMTEMQGGKYLPLGDERCTHLVVEEN------------------------------------------------------------------------------IVKDLPFEPSKKLYVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSMLSLNTPNSNRKRRR------------------------------------LKETLAQLSRETDVSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPESSINYGDTPKSCTKSSKS-----------------------------------------------------------------------------------------------------------------------------------------STPVPSKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDIFLKYSKDLVKTYPPFVNFFEMSKETIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETISLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHGQTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSDELPKENWLKMLCRHVANTICKADAENLIYTADPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRRALMTSHGSVEGRSPSSNDKHVMSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQ97-1", "uniprot_id": "Q8IQ97_DROME", "id": "Q8IQ97-1", "name": "", "aln": "------------------------------MEMETIEEQSKCEMSITTLPTRICLVGGVGQDADTLQAAESFGLPIVTSDTGLDILG--------------------------------ESSDWRTFYVLDDFEGASFEAIHKQKECILGPPALKYAAEMKQTLGQNSRPIYNYAMRGVVTCFTGIRKKDELTKLVNLIHSMGGCIKKDLNTKTTHLICNHSGGEKYQYAKTFRLTVVRPAWVFAAWADRNSLEFDATQENFTKTHRLKAFEGQKICFFGFPVEEHQHMVDVLLENGGVCAELDDPECSHVVMPNTGAVFTSTSTSTDTNPSTLINPPESQVPGSSSASQAGEEEQRKAEHLEQAEIKKMEYSHAETDNGMSLDIDQEQKENQGIEDEDDIHFDERLFVEAADIINHGEDQLPESDEEDLEEEQKPKVEEVLKEQEVEEDVQASTPKTSKIRTSLKAATPLSSPEMDGIALDFESTTQNISPILKAIDECDLETDDLPPSENDLKRKRESFDNVSLMSVDSFALPASTKKPKLIRTGSISRTLRRSVSFVAEPLMKTLRPRRSSVADASSFVGSEAADNSICSLASSINLTLNDSIRKPVKEKLRSFCGRITRSSSRRHDRGVDGTPECTTLLDSGFKTPKAPKLRSTATPKTAKRLFGPVSGVVSALTLTNPSTPTPNPNPNTNCTATLDVNDTSIHTFAFCAAAVTPAMPPSSSSSSSSPILSTSIAVHSSVQVIKSPEESTTRRNSPAPIEEPMAMVVDEHTTLTKPEPKNNHTHILKSDWFWYTIQNGYANEMDYLFGDYLDSITNTPNTDRRDSLPISFNKRKRKRFSQRIQLEGTPLGSGKRRSSVSDAGLLSVSNSLFDCTTSPDKLESDKLLHAEPEASDATPAKKSMRFNHFMDFYTTESNYVGILDTILNLFKNKLEELAETNDPLLNKSEIKTIFGNFLPIHEVHQSMLEHLRKLHANWREDCLIGDIIIQHRDELIKAYPPYVNFFEQMKEQLQYCDREYPRFHAFLKINQTKPECGRQGLQDLMIRPVQRLPSISLLLNDILKHTTSGNADHGRLEEALKAIKQVTLHINEDKRRTESRMAIFDIFNDIEGCPAHLVSSNRSFILKCEVNELSDSLSGRGDSLVLYLFSDSIELCKRRSKGFNTAKSPS----TAKTHKHLKLISLNTIRLVIDISDSP---RAFGLLLR---GDKEKLYTFTISDEETDKSVYVKKLCNQIAAHTCRTDADKLLICRTSQELEVDISDVNVSTLSKAFKLAAKTRLKVGRAFSFNKTPNKLKRAVSTMMTSPFGSTNSLTPAS--QLAQMRLASCTNINEVDDEDCASMRSSSPSTQSEMLVVPPLSVQPTRKNKAVVGRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 289, "similar_positions": 320, "identity": "20.87%" }, { "cls_id": "homologset.agr.HGNC:3157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MIW0-1", "uniprot_id": "A0A096MIW0_RAT", "id": "A0A096MIW0-1", "name": "Ectodysplasin-A", "aln": "MGYPEVERREPLPAAAPRERGSQGCGCRGAPARAGEGNSCRLFLGFFGLSLALHLLTLCCYLELRS--------ELRRERGTESRLGGPGAPGTSGTLSSPGSLDPVGPITRHLGQPSFQQQPLEPGEDPLPPDSQDRHQMALLNFFFPDEKPYSEEESRR--VRRNKRSKSGEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--TTVMGPPGPPGPPGPQGPPGLQGPSGAADKTGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLH-------------------PRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTN-YNTCYTAGVCLLKARQKIAVKMVHADISINMS--KHTTFFGAIRLGEAPAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54693-1", "uniprot_id": "EDA_MOUSE", "id": "O54693-1", "name": "Ectodysplasin-A", "aln": "MGYPEVERREPLPAAAPRERGSQGCGCRGAPARAGEGNSCRLFLGFFGLSLALHLLTLCCYLELRS--------ELRRERGTESRLGGPGAPGTSGTLSSPGSLDPVGPITRHLGQPSFQQQPLEPGEDPLPPDSQDRHQMALLNFFFPDEKAYSEEESRR--VRRNKRSKSGEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--TTVMGPPGPPGPPGPQGPPGLQGPSGAADKTGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLH-------------------PRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTN-YNTCYTAGVCLLKARQKIAVKMVHADISINMS--KHTTFFGAIRLGEAPAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92838-1", "uniprot_id": "EDA_HUMAN", "id": "Q92838-1", "name": "Ectodysplasin-A", "aln": "MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRS--------ELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRR--VRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--TTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLH-------------------PRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTN-YNTCYTAGVCLLKARQKIAVKMVHADISINMS--KHTTFFGAIRLGEAPAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MUJ1-1", "uniprot_id": "EIGER_DROME", "id": "Q8MUJ1-1", "name": "Tumor necrosis factor family member eiger", "aln": "--MTAETLKPFITPTSANDDGFPAKATSTATAQRRTRQLIPLVLGFIGLGLVVAILALTIWQTTRVSHLDKELKSLKRVVDNLQQRLGINYLDEFDEFQKEYENALIDYPKKVDGLTDEEDDDDGDGLDSIADDEDDDVSYSSVDDVGADYEDYTDMLNKLNNAHTGTTPTSETTAEGEGETDSASSASNDDNVFDDFTSYNAHKKKQERKSRSIADVRNEEQNIQGNHTELQEKSSNEATSKESPAPLHHRRRMHSRHRHLLVRKGESLLSARSEDSRPAAHFHLSSRRRHQGSMGYHGDMYIGNDNERNSYQGHFQTRDGVLTVTNTGLYYVY--AQICYNNSHDQNGFIVFQGDTPFLQCLNTVPTNMPHKVHTCHTSGLIHLERNERIHLKDIHNDRNAVLREGNNRSYFGIFKV------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :..::..: * . . *.*: : *.***:**.*.: :*:* : * .*:* . .: * . . . :.. . . * .. ::: * .: *.:* . : :: . .* : *:: .: .: .. ..* *:* :... .. :. . . . .. : .*..: . .: * ..: ... :.*: .: :..: :: :*:. .:* .. . * : : * .*.* * * * *::* .:: * * * .: *. .:.***** .:: *. .: :**:*:*: *: .::* :* :* * . : :: ::** ::: ", "identical_positions": 60, "similar_positions": 149, "identity": "14.12%" }, { "cls_id": "homologset.agr.HGNC:316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89020-1", "uniprot_id": "AFAM_MOUSE", "id": "O89020-1", "name": "Afamin", "aln": "MRHLKLTGFIFFLLPLTESLALPTKPQDVDHFNATQKFIDENTTYLAIIAFSQYVQEASFDEVETLVKVMLDYRDRCWADNTLPECSKTANDAIQDMLCDMEGLPQKHNFSHCCGKAGFPRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLHLYMYEVARRNPFVFAPVLLAVAAWFEEAATTCCEQQQKATCFQAKAAPITQYLKASSSYQRNVCGALIKFGPKVLNSINVAVFSKKFPKIGFKDLTTLLEDVSSMYEGCCEGDVVHCIRSQSQVVNHICSKQDSISSKIKVCCEKKTLEREACIINANKDDRPEGLSLREAKFTESENVCQERDSDPDKFFAEFIYEYSRRHPDLSTPELLRITKVYMDFLEDCCSRENPAGCYRHVEDKFNETTQRSLAMVQQECKQFQELGKDTLQRHFLVKFTKAAPQLPMEELVSLSKEMVAALTTCCTLSDEFACVDNLADLVLGELCGVNTNRTINPAVDHCCKTDFAFRRHCFEHLKADTTYELPSVSALVSALHTDWCQPRKEDLQNKKHRFLVNLVKWMPGITDEEWLCLFTKFTAAREECSEVQEPESCFSPESSKTGDESQATEKQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36953-1", "uniprot_id": "AFAM_RAT", "id": "P36953-1", "name": "Afamin", "aln": "MRHLKLTGFIFFLLSLTESLALPTKPQDVDHFNATQKFINENVAYLTIIASAQYVQEASFEEVEMLVKVMLDYKDRCLADSTLPECSKIANDAIQDMLCDMKGLPQKHNFSHCCRQAGFQRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLNLYMYEVARRNPFAFAPVLLNVAARFEEAATTCCEQQQKATYFQDKAAPITQYLKALSSYQRNVCGALLKFGPKTLNSINIAVFSKKFPKIGFEDLTSLLEDVSSMYDGCCEGDVVQCIRSQSQVMHHICSKQDSISSKIKACCEKKLPERADCIINANKDDRPEDLSLRTPKFTDSENVCQERDSEQDKFFAEFLYDYSRRHTELSTPELLRITKVYKDLLEDCCNRKNPLSCYRHAEDKFNETTERSLAMVQQECKQFQELGKDALQRHFLVKFTKAAPQLPMEELVSLSKEMVAALATCCTLSDEFACVDNLADLVLGELCGMNKNRTINPTVDHCCRADFAFRRPCFEHLKADTTYALPSVSALVSALRADWCQPLKEDLQNKRHRFLVNLVKWMPEITDEERLCLFTKFTAAGEECGNIQKPEACFSPESSKTGDVSQDAEKQR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43652-1", "uniprot_id": "AFAM_HUMAN", "id": "P43652-1", "name": "Afamin", "aln": "MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: **********: *****:***:*:*:::**:*****::* *::*** :******:*:*:* *** *::*:*** **.******* .*:.:*: :* *:************ :.. **********::*******************:.* **:*: ::*********.***.** **. ***.*.:***:*:*.. :* :* *:****** ****::*****:***.*.:: * :*::*:***** *::* :*:***** *:********:***. *:*::************** ***** ** ****:******:.**** ***:*********:: *.***:* ::*****.:** ******.::* *:*.:**. :** .***:.********::** *******:**:**** *: *:*:::** ****. ******.::**:*::******:************:*****:* ******:*****:::***** *** ****.** *..* : ::::* **. :*:**.* .******** :**** .***:*: . ::* : :.** **. **.* *: ", "identical_positions": 384, "similar_positions": 145, "identity": "63.16%" }, { "cls_id": "homologset.agr.HGNC:3164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60869-1", "uniprot_id": "EDF1_HUMAN", "id": "O60869-1", "name": "Endothelial differentiation-related factor 1", "aln": "---------------------------------------------------MAESDWDTVT---------------VLRKK---GPTAAQAKSKQAILAAQRRGEDVETSK-KWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMG1-1", "uniprot_id": "EDF1_MOUSE", "id": "Q9JMG1-1", "name": "Endothelial differentiation-related factor 1", "aln": "---------------------------------------------------MAESDWDTVT---------------VLRKK---GPTAAQAKSKQAILAAQRRGEDVETSK-KWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L496-1", "uniprot_id": "A0ABK0L496_RAT", "id": "A0ABK0L496-1", "name": "Endothelial differentiation-related factor 1", "aln": "MWRHPKNVGTQVSTCKARVCCGIACLMVWCGGTPGNCQEQRLGSQEIFLTCRHSSGWHEISGIVPSHLLPATVGRFRFRPRKMLGLACQSGVHLKSFPCADCKPHSVPLTLPAGAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBY3-1", "uniprot_id": "EDF1_DANRE", "id": "Q6PBY3-1", "name": "Endothelial differentiation-related factor 1 homolog", "aln": "---------------------------------------------------MAECDWDTVT---------------VLRKK---GSAAQSK-SKQAVTAAQRKGEAVETSK-KWAAGQNKQHVVTKNTAKLDRETEELSHQRVPLEVGKVIQQGRQNKGLTQKDLATKINEKPQIIAEYECGKAIPNNQVMGKIERAIGLKLRGKDIGLPLEACSKK-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFR6-1", "uniprot_id": "M9PFR6_DROME", "id": "M9PFR6-1", "name": "", "aln": "-----------------------------------------------------MSDWDSVT---------------VLRKK---APKSSTLKTESAVNQARRQGVAVDTQQ-KYGAGTNKQHVTTKNTAKLDRETEELRHDKIPLDVGKLIQQGRQSKGLSQKDLATKICEKQQVVTDYEAGRGIPNNLILGKMERVLGIKLRGKERGQPIAPPGKKXNDAAASAASGAPHTVTSGRSARQQNHQHTDSGGWSTVSGRRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O14467-1", "uniprot_id": "MBF1_YEAST", "id": "O14467-1", "name": "Multiprotein-bridging factor 1", "aln": "-----------------------------------------------------MSDWDTNTIIG-----------SRARAGGS-GPRANVARSQGQINAARRQGLVVSVDK-KYGSTNTRGDNEGQRLTKVDRETDIVKPKKLDPNVGRAISRARTDKKMSQKDLATKINEKPTVVNDYEAARAIPNQQVLSKLERALGVKLRGNNIGSPLGAPKKK-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*. : * . . . * : * .: .: . :. :*:****: : .:: :**: *.:.* .* ::******** ** :: :**..:.***: ::.*:**.:*:****:: * *: : ", "identical_positions": 39, "similar_positions": 49, "identity": "15.0%" }, { "cls_id": "homologset.agr.HGNC:3165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48303-1", "uniprot_id": "S1PR1_RAT", "id": "P48303-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "MVSSTSIPVVKALRSQVSDYGNYDIIVRHYNYTGKLNIGVEKDHGIKLTSVVFILICCLIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIMGWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNIS--KASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIISCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSHPQKDDGDNP--ETIMSSGNVNSSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08530-1", "uniprot_id": "S1PR1_MOUSE", "id": "O08530-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "MVS-TSIPEVKALRSSVSDYGNYDIIVRHYNYTGKLNIGAEKDHGIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIMGWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNIS--KASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIVSCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSHPQKDDGDNP--ETIMSSGNVNSSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21453-1", "uniprot_id": "S1PR1_HUMAN", "id": "P21453-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "-MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNIS--KASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNP--ETIMSSGNVNSSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDK4-1", "uniprot_id": "S1PR1_DANRE", "id": "Q9DDK4-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "---------------------MDDLIARHYNFTGKFRK-VHKDPGLKADSVVFIIVCCFIILENVLVLLTIWRTKKFHKPMYYFIGNLALSDLLAGVVYTANILLSGANTYKLTPTQWFFREGSMFVALAASVFSLLAIAIERHLTMLKMKLHNNGKTCRVFMLISTVWFIAAILGGLPVMGWNCIDSMNNCSTVLPLYHKAYILFCTTVFSVILMAIVILYARIYALVRTRSRKLVFRKVANGRGSNKSSEKSMALLKTVIIVLSCFIACWAPLFILLLLDVACQTLTCSILYKAEWFLALAVLNSAMNPLIYTLTSNEMRRAFIKMLNCGVCVQ--PSGKFSRPIMG-AEFSRSKSDNSSHPNKDEPEYSPRETIVSSGNITSSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.****:***:. ..*: .:* *****::**:*****::******:*****:******************.****:*****.******:***:*********:*************::*********..:. * *:***: *.*: ******:******.::..********** *********:::*::*****.***:*******:*.*** . :.:*****:*********** ****************.*:. **.**::**:**.******. **:*****.:*******:::.* * . .:***.***: *************:**: : . ***:****:.***", "identical_positions": 253, "similar_positions": 81, "identity": "65.37%" }, { "cls_id": "homologset.agr.HGNC:31652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPX2-1", "uniprot_id": "A0ABK0LPX2_RAT", "id": "A0ABK0LPX2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAWQDGGAKAAPSHHKISFSVLDILDP----------------------------------QKFTRAALPPVRLAALEAKKSLVEVEAG---------------------EDACSGNPIGSQETPDAVGGGTDPASPVEGSEAEEEEEAEDAGRAQRPERWQGAHAG---SLEAGAVAVGTEESGADG-----------------LPASPGSPGSPRPRRRRAE------------------------------------------------------------SSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAVQAGGSAPQPGTPNAVTGGGGSATGSSPGPPVPGALPFQTFPTYPATNVLFP-AASFPLTTTATGSPFTPFLGPPYLTP-FYAPHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42580-1", "uniprot_id": "NKX12_MOUSE", "id": "P42580-1", "name": "NK1 transcription factor-related protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAWQDVGAKAAPSHHKISFSVLDILDP----------------------------------QKFTRAALPPVRLAALEAKKSLEEVEAG---------------------QDACSGNPIGSQETPDAVGRGIDPGSPVEGSEAEEEEEAEDAGRAHQPERWQGVHEG---SPEARAVAVGTEESGAEG-----------------LPASPGSPGSPRPRRRRAE------------------------------------------------------------SSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAVQAGGGAPQPGTPGAVAGGGGSATGSSPGPPVPGALPYQTFPTYPATNVLFP-AASFPLTTAANGSPFTPFLGPSYLTP-FYAPHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UD57-1", "uniprot_id": "NKX12_HUMAN", "id": "Q9UD57-1", "name": "NK1 transcription factor-related protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAWQDGGAKAAPSHHKISFSVLDILDP----------------------------------QKFTRAALPAVRPAPREARKSLAEVEAG---------------------KDASSRDPVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGP-------------VRSPPGSPGSPRPRRRRLE------------------------------------------------------------PNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPG---AAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPFLGPSYLTP-FYAPRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A4P8-1", "uniprot_id": "B8A4P8_DANRE", "id": "B8A4P8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEYQESGGKGT-SDHRISFSIIDILDP----------------------------------TKFTSKKT---DVSEKERTSSSENTGFG---------------------SLEESRNGKHSDGECESTGDRSDDRHGCVRLHPPDPDVDFDCSSSHR-----SLKSG-------FSPCEDPDEAAEER-------------------MTPAPDDVSRQRRRRSD------------------------------------------------------------HSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGVESSLQAG---------------TNSLPNISPSCGSASALH----PPFSTGNMIFH---SGPVHLASSAGLLHPFLTDGFLQPAFFPPHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22807-1", "uniprot_id": "SLOU_DROME", "id": "P22807-1", "name": "Homeobox protein slou", "aln": "MVMLQSPAQKASDSASAQNTAVGGLMSPNSNPDSPKSNTSPDVASADSVVSGTGGGSTPPAAKIPKFIISANGAAVAGKQEQELRYSLERLKQMSSESGSLLSRLSPLQEDSQDKEKPNHNNNNSLTNHNANSNTRRSQSPPASVGSVSFSSPAQQRKLLELNAVRHLARPEPLQHPHAALLQQHPHLLQNPQFLAAAQQHMHHHQHQHHQHPAHPHSHQHPHPHPHPHPHPHPSAVFHLRAPSSSSTAPPSPATSPLSPPTSPAMHSDQQMSPPIAPPQNPPHSSQPPQQQQVAAPSDMDLERIKLVAAVAARTTQASSTSALASASNSVSNASISISNSSSGSPSGRDLSDYGFRIQLGGLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGSHSTPSVCPVDLTRSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPSGPFGHPRQWSYERDEEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMD------------------------VNSPTIPPPGGGSFG----PGAYASGLLYS--------HAVPYPPYGPYFHPLGAHHLSHSHS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *.:::* .: :* : : : * : * : . . . . . : . . : . . . .... . .* . : . :***************:*****::**************************************** : . : .:: * : .::: : *:: .. ", "identical_positions": 68, "similar_positions": 56, "identity": "9.77%" }, { "cls_id": "homologset.agr.HGNC:31653", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5VZQ5-1", "uniprot_id": "TEX36_HUMAN", "id": "Q5VZQ5-1", "name": "Testis-expressed protein 36", "aln": "MTKGRRFNPPSDKDGRWFPHIGLTQKTPESITSATSKEPQSPHLPR---QAEGKLPPIYKVREKQAVNNQFPFSVHDNRHSLENSGCYLDSGLGRKKISPDKRQHVSRNFNLWACDYVPSCLDG-------FSNNQISYVYKEAMVVSSFRRFPRCYKEIWNAFTFLPERSYTEVLKKKPKVRFTVDKKVVSSLES---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WCA3-1", "uniprot_id": "X1WCA3_DANRE", "id": "X1WCA3-1", "name": "", "aln": "MSKGGKRYFNKNKSVNWFVHTGFSQTEQTHHLCTSTGSALAHAVSQPLTPSEQRYPKVFINPEKKTMGREYPLSMHDNRTALQQCIDVYDQGSGRKKCLDERRQHNSHYSLRHHHHGTPSLVTAVKWEDSVYQKDFLPRQQIESREDKIRRRFPRDHSARSQVNAAAQADQCFMWFGRDDAKQFTPLSVLADANHSLTT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** : .:*. .** * *::*. .::: .. : :.: :* : * :: **:::..::*:*:**** :*::. *.* **** ::*** *: . .** : . :.:: :. *: . ***** :. :. : . : :. :** . :..: .* ", "identical_positions": 41, "similar_positions": 68, "identity": "20.6%" }, { "cls_id": "homologset.agr.HGNC:31658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2U6-1", "uniprot_id": "D4A2U6_RAT", "id": "D4A2U6-1", "name": "", "aln": "---MKLQVFWTG----------------LEYTCRLLGITTAAVLIGVGTETFLRGRFKSLAFYLLFTGVTISVCEGTYFVAQLLAICFKCQ----PGSLAHRAKEKAHWLGCFQKFLAYMLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKKKAAPEVMPPTEQYRDPSSSIVSTTGSGDTEQTYTFHEAFKEGPSSFLIH----------MKSILKGTKKPRVLQAQDTLMELALEPADSLAKK-KQVHFEDNVVRIIPSLTEG---LGDSDSGPEETSSDTTPIIPPSQTP-LFLPS-----------LMATDLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3K5-1", "uniprot_id": "TMM72_MOUSE", "id": "Q8C3K5-1", "name": "Transmembrane protein 72", "aln": "---MKLQVFWTG----------------LEYTCRLLGIATAAVLIGVGTETFLRGRFKSLAFYLLFTGVTISVCEGTYFVAQLLAICFKCQ----PGSLAHRAKERAHWLGCFQKFLAYMLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKKKAAPEVAPPTEQYTDPSSSVVSTTGSGDTEQTYTFHEAFKEGPGSFFIH----------MKSILKGTKKPRVLQTQDTLMELALEPADSLAKK-KQVHFEDNVVRIIPSLTEG---LGDSDSEPEETSSDTTPIIPPSQTP-HFLPS-----------LMATDLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PK05-1", "uniprot_id": "TMM72_HUMAN", "id": "A0PK05-1", "name": "Transmembrane protein 72", "aln": "---MQLQVFWTG----------------LEYTCRLLGITTAAVLIGVGTETFLQGQFKSLAFYLLFTGAAVSICEGAYFVAQLLAICFQCQ----PGSLADRVREKAHWLGCFQKFLAYLLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKRKAAPEVLASPEQYTDPSSSAVSTTGSGDTEQTYTFHGALKEGPSSLFIH----------MKSILKGTKKPSALQPPNTLMELSLEPADSLAKK-KQVHFEDNLVRIVPSLAEG---LDDGDSEPEETTSDTTPIIPPPQAP-LFLSS-----------LTATGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P9W7-1", "uniprot_id": "A0A8M1P9W7_DANRE", "id": "A0A8M1P9W7-1", "name": "", "aln": "---MKGSALWVI----------------VECSCRVLGISTAAVLCAVGIETQSQGEFTSLAVYLLLSSLVIMIFEVAYFIDALLATCLPCP----PTWKMFILWKKMAKVGGFQKFLYYTMMSVMCFLHPVLVWHAVIPGIMLVVTGFFNFILSKKKKSDVPKE---SRVFYGDPALSSVCVKDRGDSEDTFSFFNVISGKRASFIPNNSRIHDLTDRDQSLKNGQHKKRQTDRRNVHFIKSLRSNDTEMEEYHEVESEETTSDKAPMITLVSCWKKKENCFLFQSVTLSLGLLHPSIHPSIRLHTSIQLRDSIHHLLTQTRRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVY1-1", "uniprot_id": "Q9VVY1_DROME", "id": "Q9VVY1-1", "name": "Transmembrane protein 72", "aln": "MSQMQLQSQRVRRARHHRRNQSAEPCECLRPVIRVFGLLTSFVICGVGVDVYMHG--YRAGLYIVFSAVLVMFIEIKWLVTIFLQLQCAEDNYQRRSCSCLACWRLSAICGGWRPTPVYAVIGICLILYPHNLWLSYVAGMFLILLGLLRLCTLLRFS-----------------ASKEEGLLPQCDFEKVSSFVDTMEDDFAEIGAT-------------------------------QAGLDEEAEEEGD-DHTALDDDVC-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . :. *::*: *: *: .** :. :* ..*::::. : . * ::: :* . * :: * ::.: :*:* :* :.* :*:: *: : : . : . * *.. :* .:. ..: .* . ... :: ", "identical_positions": 23, "similar_positions": 64, "identity": "7.1%" }, { "cls_id": "homologset.agr.HGNC:3166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61794-1", "uniprot_id": "LPAR1_RAT", "id": "P61794-1", "name": "Lysophosphatidic acid receptor 1", "aln": "MAAASTSSPVISQPQFTAMNEQQCFYNESIAFFYNRSGKYLATEWNTVSKLVMGLGITVCVFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIDHCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRNENPNGPTEGSDRSASSLNHTILAGVHSNDHSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61793-1", "uniprot_id": "LPAR1_MOUSE", "id": "P61793-1", "name": "Lysophosphatidic acid receptor 1", "aln": "MAAASTSSPVISQPQFTAMNEQQCFYNESIAFFYNRSGKYLATEWNTVSKLVMGLGITVCVFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIDHCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRNENPNGPTEGSDRSASSLNHTILAGVHSNDHSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92633-1", "uniprot_id": "LPAR1_HUMAN", "id": "Q92633-1", "name": "Lysophosphatidic acid receptor 1", "aln": "MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *** ************* *****************:********************:***********************************************************************************************************************************::**************************************************************************:*************************************************************.***.*****************************", "identical_positions": 354, "similar_positions": 7, "identity": "97.25%" }, { "cls_id": "homologset.agr.HGNC:31666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LK01-1", "uniprot_id": "A0ABK0LK01_RAT", "id": "A0ABK0LK01-1", "name": "", "aln": "MKKLSKRREEIFRKMSEAAT-SSTEEIMDRRLSKGSPAEENRNITETLRGKVREKLKHAKISQGEKSSAELLADTRTCRWS----KTEVLLDEGLSFFILSGEEDSAASRSSRQKTVSESYFKHCASGGGFQIATEGQDEDFMEEVILTDLFEVKAAKYEDDQELIKKQEATIFVPSSSPVASQQKLPKGVLPRILEDEGLYTQKKPETCKKICNKMENRLLSLQEGKCWFEESGEIMSLPSPLRQSWN--FRLCMCKESLNPALKTIHRKAEKYDVGCCFRNRMDGQRETYQLDLNIVGLQFSHHPLFNQEQVLCARLLQLCESFQDRQKQSLSQLLYEKLRALKDATKLASKNPESSQFTKKSLQD------YYQQISDTEQLYDAEREKDHCLLHSVSQTWKQIKS-LRQKQGFTSTPVKLQFHRIKMNTWDEQNQVGMSEGPGDESEETPFPKEDPQETLSHPASDPEGLEAERRKPITLAPQLSFTAELTNIS---KCSLYEQKRRAKMQKLKYFIKIFYNDKQVSCTSVSPLQLDFKVMFQQIFNIQLMYWPETICLEVYEIRKRSTLLVKMYLPLPNKTELKGKTALEYTEFSSDKLVIPMDGGVGSNVPFNLEESENEELCLLTSGKLSYSLSWALDENGMPLTPVSQSLNSAYCSVLRNVDARGVPGLPWIVNSQKLCDWADDIRIDPNNPEYSDITELIMYLRHKGQEIPKYFR--LDQLQDEFNFVSEEEMKRSKRFQLLELRNAG-QLDLFLLQQMPLYDNEIP-DIVFQEFESQAQKDVSISDVNSITAQRINSVNFLRKVRRLIMKKIVKVSKFNLS-----DIVADYEEIVST--SQLTDALCKFIEPRRKLKPQRKERRK-VTAQSISDGDIKILVRILRAYNIPTRKTTSYRTWSMPTYLSSSMSYLRYQNEAKLVPSNEVINEDTVHPFIEVSFQHTVYQTNIANGSHPCWNEEIKVDFISPGHDYSFSSLSKIKDNIHINVFDEVVIEKHEDHCLKSCSAHSYIQKNWLGSISFPFSALLQQPEISGTFQVNIPPILLGYTWSNTYVSPREDCSGQ-NPKECTFLNIFATIEP-QISYVMYNPKVDEFSDQIDILQRAQTFTRNCKAMFPS--RRVMATVFNGEGMQILVTRYIKALNPPQQLLDIFLHDSNATLDLIARFVSLIPFAAETLDENDGADIWMTSECCISLAIGSKEEHAILLCNFFLYFGKKALVILGTSVLEGHVAYVLT--QETGECLLWNPSTGQCYKQFDPFCPLQSVDCLFNDKNVWFNIQQNNTPMAVHFDCSKESFWKQLLPKNFQWTKAQSVQPEEIVYLDTNKSMVEDLKSRIERALKCKMMEWRPKHPTRWNRQCTSVLRQILPKLE----FYTGSFASFE-DSELERLLQFYWVTGFPIQMPYTDVQAVIDAVYQTGVHSSEFPQTEFALAVYIHPYPNNILSVWIYLASLARHQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LIW0-1", "uniprot_id": "A0A140LIW0_MOUSE", "id": "A0A140LIW0-1", "name": "", "aln": "MKKISKRREEIFKKMSEAAN-SSTEEMVDRHLSK----EENRNITETLRGKVREKLKNAKISQGEKSSAEPLTDTKTYRWS----KTEVLLDEGLSFFILSGEEDSAVSQSSQQKTVSESYSKQSASGGGFRNTAEGPDEDFMEEVILTDLFEVKAADYEDDQEQIKKQEANIFVPSSSPVASQQKLPKGMLPRILEDEGLYVQKKPETYKKICNKMENRLLSLQEGKCWFEESGEIMSLPSPIRPSWN--YRLCMSKESLNPALKTIHRKAVKSDVGCCFRDRMDGQREMYQLDLNIVGLQFSHHPLFSQEHVLCARLLRLCESLQDRQRQSVSQLLYEKLRALKDATKLISKNPELSQFTTKSLQD------YYRQISDTKQLYEAEREKDHSLLHSVLQTWKQIKS-LRQKQGFTSTPVKVQFHRVKTNTWDEQNQAGVSEGPGDGSGETPLQNEDTEETLSHPASDPEGTEVEKTKPITLVPQLSFTAELTNLS---KCSF---------------------------------------------------------------------------------------------------------------------------------------------------------------VLRNVDARGVPGLPWIVNSQKLCEWADDARIDPHNPDYSDITEHIMCLRHKGQEIPKYFR--LEQLQDEFNFVSEEEMERSKRFQLLQLRNAG-QLDLFLLQPMPLYDNEIP-DIVFQ-------------------------------VRRLIMKRIVKVNKFNLS-----DIVADYEEIVST--SQLTDAICKFIEPRRKLKPQRKERRK-VTAQSISDGDMKILVRILRAYNIPTRKTVSYS---------------------------------------------------------------------SPGHDYSFSSLSKIKDNIHINIFDEVVIEKHE---------------------------------ISGTFQVNIPPILLGYTWSNTYVPPREDCSGQ-NPKECTFLNIFATIEP-QISYVTYNPKVDEFSDQIDILQRAQTFTRNCKAMFPN--RRVVATVFNGEGMHILVTRYIKALNPPQQLLDIFLHDSNATLDLIARFVSLIPFAAETLDENDGSDIWMTSECCISLAIGNKEEHAILLCNFFLYFGKKALVTLGTSVLEGHVAYVLT--QETDECLLWNPSTGQCHKQFDPFCPLQSVDCLFNDKNVWFNIQQNNTPMAVQFDYSKESFWKQLLPKNVQGTKAQSVQ-----------------------------------------------------------------------------------VTGFPIQMPYTDVQAVIDAVYQTGLHASEFPQTEFALAVYIHPYPNNILSVWVYLASLARHQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DHV5-5", "uniprot_id": "C2D2B_HUMAN", "id": "Q6DHV5-5", "name": "Protein CC2D2B", "aln": "MKKS--QREDIFKKMSEEMDNITAEEIIDKHLQKDLDAEENQNVAKTLRGKVREKLKISKINKGEKSSTEQLIDSEIHQRSKLSPQTEVSLDESLSFFILSGEEGSALGKSSEQRPVNRSYPKCFSLGVNLQNVAESEEEEFMKEFILTDILKVKAADYEDDQEQIKKQKANIFVPSSSPVVNQRKLPKDMMPRILEDEGFYIQRKPEIYKKTCNKMENRLLKLEEGKCWFGESGEIMSLPTPIKQSWN--FRLNVRKEPLNPLLKTIYRKAVKYDLGSSFMNKMEGSREIYQLDLNIVGLQFSHHHLFNQEQVLCARLLQLYECFQDRQQQNVSQLLYEKLKALTDATKLSNENSEINQLTRKSLQD------YYWQISNTKQMYDLERGKDLSLLHSILRTWKQIKS-LRHGQGFTSTPIKLQVQRIKMNKCDEQEQISEMSETEKKNEGKELKNGKKLESLSYLASD--ETEIERIKPITLRPQLSFTAELTSLS---KCSLHEQKRRAKIQKLKYFIKIFYNNKQVSCTSVSPLQFDFKVMFQQIFNIQLMYWPEVICLEVYEKSKRTSLLAKLYIPLPNYTELKGKTALQYVEFSSDKLVMPADGEVGSNVPFLLEGNGTEELCLLTSGKLSYSLSWSLDENGLPLIPMPQSLRSSYCSMLRNVDARSVPGIPWLMNEQKLFEWANEVRIDPNNPEYSDLMESVTYMRLKGQDIPKYFR--LEQLQDEFNFVSEEEMAKSKRFQLLQLRNAG-QLDNFLLQQMPLHDTEIP-DLVFQEYESQKEKEVSVSDVNSITAQRINSANFLKKVRRLIMKRIVKISKCNLS-----DIVNDYEEIVST--SQLTDAVCKFVEPRRKLKPQRKERKK-VTAQAISDGDIKILVRIVRAYNIPTRKTTINGSLDMPTCLKSSISCLRHRETIKSVASDETLHEDTVHPFVEVSFQHTVYKTNTASGSHPCWNEEIKVDFVSPGHDYSFSSLSKIKDNIYINIFDEMMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEISGTFQVTIPPVLLGYTWSNTYVFPKEDSNEQ-NLKECTFLNIFATIEP-QISYVTCNPTLDKFLDQTEVLQRAQIFKKNCKAMFPN--RRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYVVT--QETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKESFWKQLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPKHPTHWNRQCTFILRQILPKLE----FGIGSFVSSEGDNEFERILQFYWVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQHQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAV1-1", "uniprot_id": "C2D2A_DROME", "id": "A1ZAV1-1", "name": "Coiled-coil and C2 domain-containing protein 2A", "aln": "MEAALSRKTAKKKRKTHTTRGYRKREQEVQKLIR----ATEGRISGPEHDMEALSLQFFHGFEGEMQQENDFAVEDCQESD----------ED------SGGELAEEPTDSPSQTFIHIDLHDPPLAWGQLFKQRHYYDESLLYRPSNTLHFQLHLSDLSELKDSQIRMLNRYQEQSKS---KSGKLGSDLIGQLSGQKPASFLMGKHLYRSVCHRRFQSVFFPPMPPSELKGLPSRRCLKLCLKQLRFSLHPQLLEEHRLAQQLEDLFDVYSQQRKQRICRKLREELEIARQVALKLLASAGQDQTAEVKRQLKLTRQLRQRYYAESAAQRNLLQRLLKEWAKLKELRRQQRFQCTRFQLGLRVVHPPDLEASYCAWKESFETDLAEVYREHLELFYTRLRLWTDQKSHSRTATGHSKPPRKPQFDRIMASLRKEYDKT-FKDPEEPYVEVFRLHADEATARLSIPGGDQLPKARNYFLKIFLDGQFVGQSRTYRLEPDLQISINECIGVLLERSLPENLNIWLYEKSTLTPK------------------------------------------------------------------------------------------SRRLAQISTPLVLSSKDDAVQEKLSFQALSSTQLAGDVYLYYEYRSTEGWGSALHLDDVQRLPDALRQTLLPQSLPALPQASKELVTPRPPSGRIKKSQLPSLIFAEQQLQFCGLDVLLDNRRFQLLHSRHQQRNLHTKQLRFVPALEQEISEEEPLPDGRGTVQLLEPGTYWNPIDLHKHRGRKFLQLLYEVIASQSARRAKALQTPLPLLLLAEDSDRSSGTGWTALWRAFCSVFQGQRNSLPREPSGWSGHQSAPDLFKSFCVSLHVVRATGVPVRSRHILNLNERRSSAGGDMS--------TSLFVTQTLMYSNVRPFVTLSYGQRLCRSRTAEGSNPTWN--------EQLQLQIQSQFGDLRDDLKISLFDELIEQQYSDEAS---DVYQRVQCNWLGEFRVPINSLLASRTFEGCIELAMPKVLVGYKRPLIDSVTNMPTDQYPEFKEAVHLWFYLSIEPGGGDLAPLHSCALACAEKPELQQYLDERRLELQQLLPQPQRYVEPLVCTAQGKRVCLTRLMDPVPLPP----AAVPSGENPLEICIRYVSLLSHLRSYDPCQGFRGVWLDNQSLLDSTWCSVKDLGVLLCNYMLSLGLECWLILGVSCPHGECSFVLFRQPETAELFLVSPATGKRYQLQDVHCPLRRIYCVVGKQNIYFNIQTETRVSMTHFNLQDGACWFPLFRRRVPAPQSGVQKLD---YAYKRSYELSQLQKHIERKIMKKISAWRTTRKTIWNRAFQPRLHKILCDMEDLSTFSRGRYDEPIFSEQLEREFPNYRLYGFTLNFAYTNLAAISERIRTSCIHYNHDASVEFCVAVHLHAHANDVLSVWLFLLSMVPLVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: :: :. .* ::* : : .:: . :. .*: : :** .. : : . . :: .** . *. * : . . : . :*.:: . * :::: :. .: :: : *.* .. ** ..:: :: :: . :. *:: : :: . : . .* :: . : :. * *: :. : . : . *: *:::. ..: :.:: :* *: :. ::.: * * :: *.: : : *: : :: * .. : :. *::: : *.: ** * *.:..* * *..*: . .* :: . : . ** ..* : * * *: :. :. : *: . .:.. . : : *:* : : : * .: : : * . * * * :::::* . : : .:*****. *: :*. *: :* : **. : : : .:* .: .: * : :. * :. .* : * *.*...: :*: *:. . . : . .: : ::::** .:*.*. . : *.:..::*:: *.:***:: :::. :.* ::: :* :*:**. . .. . : **...* :: :*** . . :. :: :: * : : : ::*. * : . * . :* :. :** :..: * : ..: .::: *:***:.. . :. .:*: .: :. : . :: .:****::* :* :. : **.* .*. ::*: ** * :* .*:**: :: * .***: : *:...:*::**** :. . *: .. : * *: :.. .: : : **.:::.* :: :: : : : :* . ...**.:**::*.:.*::****::* *:. ", "identical_positions": 156, "similar_positions": 394, "identity": "10.57%" }, { "cls_id": "homologset.agr.HGNC:31668", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M362-1", "uniprot_id": "F1M362_RAT", "id": "F1M362-1", "name": "", "aln": "------MATEVHNLQELRRSAS--LATKVFIQRDYSDGTVCQFQTKFPPELDSRIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLACATAYFIFLCMETHYEKVLKKISRYIQEQNEKVFAPRGLLLTDPVERGMRVIEISIYEDRCSSGSSSSGSSSGSGSSSAGGGGAGAR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D428-1", "uniprot_id": "GOG7B_MOUSE", "id": "Q9D428-1", "name": "Golgin subfamily A member 7B", "aln": "------MATEVHNLQELRRSAS--LATKVFIQRDYSDGTICQFQTKFPPELDSRIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLACATAYFIFLCMETHYEKVLKKISRYIQEQNEKVFAPRGLLLTDPVERGMRVIEISIYEDRCSSGSSSSGSSSGSGSSSAGGGGAGAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TAP0-1", "uniprot_id": "GOG7B_HUMAN", "id": "Q2TAP0-1", "name": "Golgin subfamily A member 7B", "aln": "------MATEVHNLQELRRSAS--LATKVFIQRDYSDGTICQFQTKFPPELDSRIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLACATAYFIFLCMETHYEKVLKKISRYIQEQNEKIFAPRGLLLTDPVERGMRVIEISIYEDRCSSGSSSSGSSSGSGSSSGGGGGAGAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KH14-1", "uniprot_id": "A0A0B4KH14_DROME", "id": "A0A0B4KH14-1", "name": "Ras modification protein ERF4", "aln": "MSQGGGTTPAGGNPTALQATGGGVVFSKVFIQRDYSEGTSVKFHTRLPAELEGMIERHVFEATINRLNEFYAEAEEGSCGTYCEGCIGCITAYLIYMCSETHYEKTLRKISKFVASQNERIYNTKGLQLIDPTYRGLRVIEITIFDRPGRTXLPLSHSANEFFM-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * *: :.. : :*********:** :*:*::*.**:. ***::** *:: ** ******: . .:* ***:.* ***:*::* ******.*:***::: .***::: .:** * **. **:*****:*:: : . * *:. ", "identical_positions": 70, "similar_positions": 49, "identity": "40.0%" }, { "cls_id": "homologset.agr.HGNC:3167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9D3-1", "uniprot_id": "F1M9D3_RAT", "id": "F1M9D3-1", "name": "", "aln": "MASTHAQGHPPVLGNDTLREHYDYVGKLAGRLRDPPEGSTLITTILFLVTCSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGRKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKKHRVFLLIGMCWLIAFSLGALPILGWNCLENFPDCSTILPLYSKKYIAFLISIFTAILVTIVILYARIYFLVKSSSRRVANHN-SERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRAKECSILFKSQWFIMLAVLNSAMNPVIYTLASKEMRRAFFRLVCGCLVKGK--GTQASPMQP-----ALDPSRSKSSSSNNSSSHSPKVKEDLP------HVATSSCVTDKTR---SLQNGVLCK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0U9-1", "uniprot_id": "S1PR3_MOUSE", "id": "Q9Z0U9-1", "name": "Sphingosine 1-phosphate receptor 3", "aln": "MATTHAQGHQPVLGNDTLREHYDYVGKLAGRLRDPPEGGTLITTILFLVTCSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGRKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKKHRVFLLIGMCWLIAFSLGALPILGWNCLENFPDCSTILPLYSKKYIAFLISIFTAILVTIVILYARIYCLVKSSSRRVANHN-SERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRAKECSILFKSQWFIMLAVLNSAMNPVIYTLASKEMRRAFFRLVCGCLVKGK--GTQASPMQP-----ALDPSRSKSSSSNNSS-HSPKVKEDLP------RVATSSCIIDKNR---SFQNGVLCK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99500-1", "uniprot_id": "S1PR3_HUMAN", "id": "Q99500-1", "name": "Sphingosine 1-phosphate receptor 3", "aln": "MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGST-LTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGR--GARASPIQP-----ALDPSRSKSSSSNNSS-HSPKVKEDLP------HTAPSSCIMDKNA---ALQNGIFCN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NC80-1", "uniprot_id": "A0A8M1NC80_DANRE", "id": "A0A8M1NC80-1", "name": "", "aln": "MDDELEPGMN-----DVIVSHYNHSGKWG-----RPRSTGMCKTAFLMCICALIVIENITVLLALWRNKRFHSRMYFLIGNLALSDLLAGVAYVVNIFTSGRNTFFLSPGQWLLREGSMFVALSASTFSLLAIGIERHMTMVRLRPCETAGRGRLLALLGACWAVSVLLSALPSLGWNCLDRVHTCSTVLPLYDKSYIAFCISVFTALLAAIVVLYVRIYQLVTSSGRRVSSRP-SDRSLALLRTVVIVLGVFVACWAPLFSLLLLDVGCSPEQCPILYKVDWFIALAVLNSALNPLIYTFSSREMRTAFLRVLCCCQTSLDSMPTVAGTALPGIVIHTAENSKSSMAGAGSGAAKSSLMQSKVPTPSNSHHQDPSQTAVTHSSGPGNLLSAVLVKAGALPALGKF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :.: .**:: ** . ... .* ::: *::**:**: **:*:*:*::**.****:******.*****:** ***: **::** *** *:**********.*** *****.****:**:::** :: : *:: *:* ** ::. *.*** ******... ***:****.*.**** **:***:*.:**:**.*** **.**.*:*:.: *:**:*********:.**:***:*** *:*:**.* : *.**:* :*** *******:**:***::*:*** **:*::* * . : *.. * : : *:*. :.:...: :*. ::..:* : .*. :. : ..:: : ", "identical_positions": 178, "similar_positions": 119, "identity": "43.84%" }, { "cls_id": "homologset.agr.HGNC:31670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRT2-1", "uniprot_id": "D3ZRT2_RAT", "id": "D3ZRT2-1", "name": "Enolase 4", "aln": "MGEEGGGRSGGISR---DLLKLKQQAMAYYQENDVPRKLEELLNSTFYLQPADVYGHL-ANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICSVAIPTHSEVVENALP--EMVDADEAERQQAVSKAVRWINQFITEELWGLIPSNQAEVDRRLRIFFEHKVQADKDRKELERSQE-EPVPMTLPVILPPPPPPP----SKKKGQKAGRRDTLLEKPIFPPEPPEPVLHGSMAIGAVSLAVAKTSATLAGTPLYLTLALLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVMCIPSPGLTTKQGIELLLEIQKQVNRAMETLPPPKPETKKGHNGGKRSQPPITGRASHLGCLTINYDTIEQPLLLIQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVGTYKS-------AAEMVELYVDLINKYPSIIALIDPFRKEDSEQWDSLYAAVASRCYLIAGAASRSVSRLLEDRNISLLKYHGLIIKHTNQTTMSDLVEITHLINGKKHLAVFGSTDSESSDDSLVDLAVGLGARFIKLGGLSRGERMTKYNRLLAIEEELIQSGAWGFSEEHNFSFFQEDAT----TTTAEETLEPLDSIFPTEVIEESAKT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C042-1", "uniprot_id": "ENO4_MOUSE", "id": "Q8C042-1", "name": "Enolase 4", "aln": "MGDEDGGRRGGITR---DLQKLKQQAMAYYQENDVPRKLEDLLNSTFYLQPADVYGHLKANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICAVAIPTHFEVVENALP--EALDAEDSERAQAVNTAVQWINQSITEELWGLVPSNQAEVDHRLRTFFEHKVQEDKERKELEKSQE-ELVPAPPPVTLPPPPPPPPPPPSKKKGQKAGRRDTLLEKPVSPPEPPEPVLHGSMAIGAVSLAVAKASATLASDPLYLTLASLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVICIPSPGLTAKQSVELLLEIQKQVNRAMETLPPPKQETKKGHNGSKRAQPPITGKVSHLGCLTINYDAIEQPLLLLQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVGTHKS-------AAEMVELYVDLINKYPSIIALIDPFRKEDAEQWDSLYAALASRCYLIAGAASGSVSKLLECRNISTLKSHGLIIKHTNQTTMSDLVEITHLINGKKLLAVFGSTDSESSDDSLVDLAVGFGARFIKLGGLSRGERMTKYNRLLAIEEELIQRGVWGFSEEHNFSFFQEDAT----ATMAEETLGLLDSIFPTEVIEESAKT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNW6-3", "uniprot_id": "ENO4_HUMAN", "id": "A6NNW6-3", "name": "Enolase 4", "aln": "MEEEGGGRSCGTTR---ELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHL-ANCFSKLAKPPTICKIVGKDVLDGLGLPTLQVDIFCTIQNFPKNVCSVVISTHFEVHENALP--ELAKAEEAERASAVSTAVQWVNSTITHELQGMAPSDQAEVDHLLRIFFASKVQEDKGRKELEKSLEYSTVPTPLPPVPPPPPPPPP---TKKKGQKPGRKDTITEKPIAPAEPVEPVLSGSMAIGAVSLAVAKACAMLLNKPLYLNIALLKHNQEQPTTLSMPLLMVSLVSCGKSSSGKLNLMKEVICIPHPELTTKQGVEMLMEMQKHINKIIEMPSPPKAETKKGHDGSKRGQQQITGKMSHLGCLTINCDSIEQPLLLIQEICANLGLELGTNLHLAINCAGHELMDYNKGKYEVIMGTYKN-------AAEMVDLYVDLINKYPSIIALIDPFRKEDSEQWDSIYHALGSRCYIIAGTASKSISKLLEQGNISIPKSNGLIIKHTNQTTMSDLVEITNLIDSKKHITVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFKEEHTFFYFNEEAEKAAEALEAAAAREPLVPTFPTQGVEESAETGASSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BC6-1", "uniprot_id": "ENO4_DANRE", "id": "Q08BC6-1", "name": "Enolase 4", "aln": "MSYKGFPSHSKVSKEDQEFYDLKNKAAEYYRSNGVPQKIESVLNEMFWQKPDDIYGYL-ANYFSGLSYTPVISKITGKEVFDGRGLTAVQAEVHCIIRNEEKMVCGAVMDGSFDGLPDGVESGEMLSNGD-LQHLSITMALKWIRENFSPVLRGFNPTDQTNVDKILSDFAMARYLEHKDSLIREKEEELRNEAMSEAPPQATPTSAPA---KDKKGNDKGKKGNITENPLPPAEPPVPRLPGATAVGAVSLAVAKTAAELLGTPLYRHITAVRDPQAQK-EMQLPVPIITIMSCGKNSAGKLNLLEEIILMPSSSLRVREVIGMGLDLQCEMRRILN--------------GSTYKALPVG--VSDEGALQVGFDRPEQALDLLAEACANLALPLGSDLHLAVNCAAHSLMDYSRGKYEVMSGCHKS-------PDELVDIYEGLINKYPAIRSLIDPFRKEDVGQWERLASVIGQSCCLLADAASNLCPRWREAKPLPP-GATKAIIRHHSDMTISDLIQS--IAEHKETILAAG-----SGDASMVDLAVGSGVSFLKLGGLRGAKRMDKYNRLMAIEEE--QEGIAGAGEINQPVSFESESG--------------------WNSLTVSAK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTS-MKFLRLR-WPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDN------DKANYHGKSVLKAVGHVNDTLGPELIKAN---LDVVDQASIDNFMIKLDGTENKSK----------------------------------------------------------FGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGN----KEIILPVPAFNVINGG-SHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIK-----------------AKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAAS----EFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFP-IVSIEDPFDQD---HWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : .: *: . .* .. . .. : . : .: . : : * * .: : *. * .:::.:: : : . . : : :: *: :.. : * **: : : *: *: .*******: * . *** :: : : :*: .::. * . .*: ::*.: :* : : : :: .:.. :: .. * : . : ::.* *: :: . :: : : .: *. *:*:: *. . ::.::* :*:.:* * :: *** :: :*: . :.. : ::: . *::: : : . : . : * : **.** .. :* *. .:*: ***::: **** . . . ", "identical_positions": 60, "similar_positions": 152, "identity": "9.36%" }, { "cls_id": "homologset.agr.HGNC:31673", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A048-1", "uniprot_id": "D4A048_RAT", "id": "D4A048-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRRETKPESDRPRK-VRFRIASSHSGRVLKEVYEDGQAPGSLDSECASVCAIDGLSDSE--------------------------------------------------------------GHQNGHIG-----LEDNEQEKDQDN--------------LLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQP-SADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q50H32-1", "uniprot_id": "GRCR1_MOUSE", "id": "Q50H32-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRRETKPESDRPRK-VRFRIASSHSGRVLKEVYEDGQAPGSLDSECASICAIDGLSDSE--------------------------------------------------------------GQQNGHIG-----SEDNEQEKDQDN--------------LLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQP-SADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCTC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MXD5-1", "uniprot_id": "GRCR1_HUMAN", "id": "A8MXD5-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKREMKPESDRPRK-VRFRIASSHSGRVLKEVYEDGQPSGSLDSECASICGIDGLGDSD--------------------------------------------------------------GQQNGHIE-----SEGDENENDQDS--------------LLVLARAASEKGFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQP-STDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGEYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDILTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSMFRNCFTDSFKALKCTACNENGLQRCKNCAG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PYD8-1", "uniprot_id": "A0A8M9PYD8_DANRE", "id": "A0A8M9PYD8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERDTSRADEERAEKRVRFRVASARSGRVLQEVFRERGLEDFADTDTTVSSEPEPERASSP-----------------------------------------------------------VISEANSHLSGLGATAEPDDSGSEPDE--------------LLMYASATKNKLFTGKRVNIFSKNGTVRGVRDKVSAGQVLFNNLSKMYG---------DSLIMNRPKRR-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4S1-1", "uniprot_id": "GRCR2_DROME", "id": "Q9W4S1-1", "name": "Glutaredoxin domain-containing cysteine-rich protein CG12206", "aln": "MAAITSNVSRLEPMRGISIIIESPEVATATPPPATTTATAEAEAATKQVAPTAKSNSNTEMSLKSQAAGMLLAFGDTAATAKDNLETSYDTAAKSTAAPETNKIYPQLLLRIGGEIAGATASAEAAASAATAAAATATSPTIISCNGEIAASQAAATAADTAATLQHNNTVKIQIESQGQQRTLGKQISVVKLNEGVEEMQQHMCYLVDTSGQYSPCETLDSGTGSDLENHPQQQQQPQQVRSPQLELHLQTTRLMVNEEADHKHSPLETPSPVPKRAYSLTDDSEECDESSNSSLSCDSLHSGGLLPTTLLRDIRFRERASGPLVTKINGRPLQFETDGYYTFHVREHENFRSFGSNSSTEYEAQHFTDEQPGED----------FVGFRDIRTAGKLAGNSTIKSAKGTVRGVKNRVRNGVATFLQLQQ-PNVKNYMEKDVGKVVLYTTSMGIIRDTYAKCANVKKILRTLLIKFEERDIFMSVEYQQEMRERMQ--DETIRVPQLFVEGQLIGDANIVERLNESGELRQLLRPYKSIATAYTCQTCGGYRMLPCPACNGSKKSMHRNHFTAEFVALKCMNCDEVGLIKCPNC--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNL4-1", "uniprot_id": "GRCR1_DROME", "id": "Q9VNL4-1", "name": "Glutaredoxin domain-containing cysteine-rich protein CG31559", "aln": "-------------------------MVLATPP----------------------------VSKGGNAGGLFMDQYQQYAAHCETADSGNGSDLESTGLPTK-----------------PDDSEESGPSSLGSDSMHGSSTEYVRQS----ASQPSG-----------------QRQRQKSLRVLGALLPDSLLRD--IRDRRSTEYVVQFS------QPEDEEKIQVPDKIPEKPSPFRLARESLSEDKIEELRAAV-ERANFVQTGEETLDSIDATSQSLPASSNIGG------------HRG-----------------------NIN---YKYADDQYYSFHINEHENFGARSARSGDEADHSTGAGSEAGSDSGILTEQQDLFAGYRDVR-CGASSTQSTIRSAKGTVRGVKNRVRNGIATFLQLQQQPNAKNFKEKDLGKVVLYTTSMGIIRETYTKCANVKQILRTLLVKFEERDVFMSVEYQAEMRQRMQ--SGQVRVPQLYVEGQHIGDAETVERMNESGELRQLLKPYKSMASTYTCQTCGGYRLLPCPSCNGSKKSVHRNHFTAEFVALKCMNCDEVGLVKCHNC--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. : .* . : * . . . :.. : .. : . .* * :******: :* * . * :* : . ::: . ", "identical_positions": 14, "similar_positions": 30, "identity": "2.35%" }, { "cls_id": "homologset.agr.HGNC:31675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5A9-1", "uniprot_id": "YTHD2_HUMAN", "id": "Q9Y5A9-1", "name": "YTH domain-containing family protein 2", "aln": "MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVAQASVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91YT7-1", "uniprot_id": "YTHD2_MOUSE", "id": "Q91YT7-1", "name": "YTH domain-containing family protein 2", "aln": "MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMNTIDQGMAALKLGSTEVASSVPKVVGSAVGSGSITSNIVASSSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVAQASVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ABJ9-1", "uniprot_id": "A0A8I6ABJ9_RAT", "id": "A0A8I6ABJ9-1", "name": "YTH domain-containing family protein", "aln": "ARRRPLLSQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMNTIDQGMAALKLGSTEVASSVPKVVGSAVGSGSITSNIVASSSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVTQTSVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKNAKRKKKVLKRNVKAVGNKKRFCIDCSNGCVCLS-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7F1H9-1", "uniprot_id": "YTHD2_DANRE", "id": "E7F1H9-1", "name": "YTH domain-containing family protein 2", "aln": "MSASSLLEQRPKGQANKVQNGAVTQKDTLNDDEFEPYLNAQPRQSNAYTAMSDSYMPSYYSPSIGFTYSLNEAAWSTGGDPPMPYLASYGQLSNGEHHFLPDAMFGQSGALGNNPFLGQHGFNFFPSGIDFPAWGNSSSQGQSTQSSGYSSSYAYAPSTLGGAMIDGQSPFAANEPLNKAVGMNSLDQGMAGLKIGAGDMA---PKVVGSGLPGGPLS-QVSTAPTMPPASMAPAKTASWADIASKPAKPQPKLKTKGGLGGTNLPPPPIKHNMDIGTWDNKGNMPKPAAPQQTSLPTNGQPPNQSSPQPGATAGGVPQLPLSNGQLVPPTGQLVQHPLPPGGQPGAVPPQLSQGPPASQPSQPTRWVPPRNRANGFG-DAAGGPGQSPPNSGMGGITVPAEPHPVLEKLRMVNNYNPKDFDWNPK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSLANKG-PLYLLFSVNGSGHFCGVAEMRSPVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLDKARQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKVEVQGSDPYSNNSSRSHYRMQDRQGRVK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBZ5-1", "uniprot_id": "YTHDF_DROME", "id": "Q9VBZ5-1", "name": "YTH domain-containing family protein", "aln": "-MSGVDQMKIPGNTAKSVEERNIPWSQQVDEASYENLSSP----THDEVSGNDNSMQFQYPPFNFKENCNTPWNNMNKGRKANANHDSYRRHGHSIPNNTRRDEHQVNPWNSRKPAAQSFRNENDQPSTKLDNRTSDEAQNQEVVAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVPSPPSPIDLGYSDLSSDFSISSNTAPP-LGARAEKVHKDTENFLKYEHKG-----------------LGNNNNFSRAKVSPTGPVRRNLGPQQPVHHAAPRP----------ATNAGPFGPPNARRHDGGPHP--------------SRNSERSGNYSSFRGSEFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLDLKKAGSARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQD-KWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSKRPPMHGPDGNNHAPAPLARSFNRQADDKDRDRDGRGGMSQKHFNSGGGAGFRNPGHRGGAGSGGSHNNYSEYRRGFDIHKSSSDYQFKDRDGPDFDRENDFGSHYGSNNRKNEYKHNNTNKARLKTRDRDFSTEQIKIGVRFKDTDKDKMRSNEYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06390-1", "uniprot_id": "MRB1_YEAST", "id": "Q06390-1", "name": "Methylated RNA-binding protein 1", "aln": "---------------------------------------------------------------------------------------MNQIWSTGPPNFYFN-----------------------------SEWKENKRNDRTIEDSLRELDGLIHSLERTHIEVQTNPKLKN--------------------------------------------------------------DVTALNDINKKENKEEITHENYT-------------------------------------HQINSIP-----------------------------------------------------LTSSNLNRHFSFSRDYNQSDNSNNNYYREYLSKPRYLQQS------TKEQTFNEINKRKSAAIIPPWLNIPENSRFFVIKSSSLKHVKRSFYNGIWSSTHFGNKRLSEAYKKLNSGA-KVFLFFSINTSGRFCGVAEMVSDLKMDLDTSIWEDEQKYGKAFKVRWVIVRDINNRSLKRFLIPSNEMKPITHSRDTQEIPYSIGISIINLFKTQDS-----DIFSFLDETYE------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : ... :.: : . . . : : * : . : * .: : . : . . .::::. :. : .*.*:*** * ..::**: **.**..*****. *::. . : *:**:* **:***:*:* : :. : :.:*.:: *: *.*:*: *:*: * *::: : .** *.:*:******:* . . .::::: : . . : : ", "identical_positions": 51, "similar_positions": 94, "identity": "6.82%" }, { "cls_id": "homologset.agr.HGNC:31677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IFT6-1", "uniprot_id": "ANO7_RAT", "id": "Q6IFT6-1", "name": "Anoctamin-7", "aln": "-----------------------------------------------------------------------------------------------------------MLRKQAGEEDSVVLIDMTSPEAGNGCSYGSTAQASEAGKQQVAPSRVGSSANP--PIDFVLVWEED---LRS---RENPTQ-----------DKTDTHEIWRETFLENLRVAGLKIDQRDVQDEAAAVHYILLSAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLENVPD--------TPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYG--HQKKGLFGIDQLLAEGVFSAAFPLHDGPFSVVPESSQVLGLTQRQVLFKHWARWGKWRKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLAGCFLVFSDVPTQELCHSSDTFDMCPLCSDCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVR-----------RMLAGSVVLLMMVAVVIMCLVSIILYRAVMAIIVSKSNNAFLSAWASRIASLTGSVVNLVFILILSKVYVILAQVLTRWEMHRTQTAFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGVRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKLCS---RRKK----AGMGANPAPWEADYELLPCEG--LFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRVYYSWTR-APDLRGFLNFTLARAP----------PTFTSAHNRTCRYRAFRDDDG-----HYSPTYWTLLAIRLAFVIVFEHVVFSTGRFLDLLVPDIPESVEIKVKREYYLAKQALADN----EALLGATGVK--------GEQPPSSEPS-----LGLPA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14AT5-1", "uniprot_id": "ANO7_MOUSE", "id": "Q14AT5-1", "name": "Anoctamin-7", "aln": "-----------------------------------------------------------------------------------------------------------MLRGQAREEDSVVLIDMASPEAGNGCSYGSTAQASEAGKQQVAPSRVGSSAKP--PIDFVLVWEED---LRN---QENPTK-----------DKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPD--------TPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYG--HEKKGLFGIDQLLAEGVFSAAFPLHDGPFSAVPESSQVLGLIQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCSDCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVR-----------RMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRSDNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFS----RGKK----AGTGTHPAPWEADYELLPCEG--LFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTH-APDLHGFLNFTLARAP----------PTFTSAHNRTCRYRAFRDDDG-----HYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQALAEN----EALLGATGVK--------DDQPPSSEPS-----LGLPA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IWH7-1", "uniprot_id": "ANO7_HUMAN", "id": "Q6IWH7-1", "name": "Anoctamin-7", "aln": "-----------------------------------------------------MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRAQEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPR-IADFVLVWEED---LKLDRQQDSAAR-----------DRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPD--------VPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYG--HEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRAR-----------RMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRL---RSKKRKAGASAGASQGPWEDDYELVPCEG--LFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTR-AHDLRGFLNFTLARAP----------SSFAAAHNRTCRYRAFRDDDG-----HYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAEN----EVLFGTNGTK--------DEQPEGSELSSHWTPFTVPKASQLQQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FD02-1", "uniprot_id": "E7FD02_DANRE", "id": "E7FD02-1", "name": "Anoctamin", "aln": "----------------------------------------------------------------------------------------------------------MMKKKKSLVEDSATLIALSDHPEQ---TYGSIEKCAKPQENKNVFSDGVT------TIDFVLVWEESGSPLKSADGDELSFS-----------SSRDTHRKWRTEFLSKLQEAGLHQEMKEVVQGKTKTTYVLLSAPWNVLCYYAEEISLRVPLQVVTTPISNWSETILEKLHIPNIMAQDVPN--------YPPDYYTCPFRTTKLERFLGHENKDTFFKTTQRHQILYEILARTPYG--ALKRGEVGIGRLVSEKVLTAAFPLHEGPFQLPKTQEDPQCLNMRQILHHYWARWACWRKYQPLDHIREYFGEKIALYFAWLGFYTGWLLPAAVVGFIIFLFGIWLMVTDVPAEELCSSGNAFIMCPLCNICSHWNLSSICYTYKAGLLFDNGGTVFFSIFMSLWAVTFLEYWKRTSSILSHRWDCSEFEEIEERPRPEFTALAPMTVRNPVTGAEEPYFPEARRLS-----------RTLTGNMVIILMISIVLIFLMAIILYRTILSIIIYRSQSAFFIFSAGRIASLTGSMLNLLVILLLSRLYTYLAQCLTRWEMHRTQTEYENAFILKVFIFQFVNFYSSPVYIAFFKGRFVGYPGSYNTLLGIRNEDCGASGCLIELAQELLVIMVGKQVISNIQEFVLPKLKTWWHKRKLKPARSQEVIDEPDTNSQINPWENDYQLLVCEG--LFDEYLEMVLQFGFITIFVAACPLAPLFALINNWVEVRLDAQKFVCEYRRPVVERAQDIGIWLTILQFISYLAVISNAFLIAFTSDFLPRLFYRYT--AGSMSGYINFTLSVAP----------ANFT-QNEMSCRYRGLRDEKG-----QNTQDYYHLLAIRLSFVIIFEHVVLLIGRIIDWIVPDIPEEVEIKIKREHYMAKEALAENQSLSKSVLEEMGRQNFELRQRIRTQSPTNNMSPTSEDEAMPAL-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q76NS2-1", "uniprot_id": "Q76NS2_DROME", "id": "Q76NS2-1", "name": "Anoctamin", "aln": "MYSAVRTNDYDYPESEMDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRNHLPTGIGVTGDGGQGGGDDEVSRRLLRTSSNISNKDKKLPITYSQWKSRTYRRFDDGKRSVDFVLAYNGETQLEEHRRKCEIFEANLQREGLQLEHNKVQR----VHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHD--------------KDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFKELSYR--HGWYKSHQDQRLVPYNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELN--------GQQKSEGELRQRNNETVIRNRDEATSFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. :* : * . .: :. . * * . : : : *. * :* ** : ..* . : : *. ** *** : :::**: :. . :: . : : : . * :. .: * :: .*: :: *:.*: ** : : . . .** :*: : * :.*:.**: *: * : **. . *.: ****::: *** *:*********** *:* :*.* : ** * :* :.::* . .:: * .* *.. * : . *:*:. **.*:: *::*** **:*** .: * :**. : : . *:***:: * . * . .. :: : : ::. ::::::.: :: : .:*:** . * .:*..:::*:.* :*. :* ** **.:* **** ::::: :* ::*****:*:* .****:**:*****..*: ::*.*:*:* ..*** **. :*::**.*** :. : *.::* * ::: : : **:*: .*. *: ******:****:*:* * *****:**:** :*:**** *:: **** **:***:* *: :: :** *.*:::**:::::*: * : .: .::****: :: *** :*:. : . *: :*: **:*:::::::: .: ***:. : ::*** :: :: : : : : * .: : ", "identical_positions": 220, "similar_positions": 266, "identity": "20.81%" }, { "cls_id": "homologset.agr.HGNC:3168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LT65-1", "uniprot_id": "A0ABK0LT65_RAT", "id": "A0ABK0LT65-1", "name": "", "aln": "MGQCY---YNETIGFFYNNSGKELSLHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGMAYLFLMFHTGPRTARLSIKGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVTLIVGVWVAALGLGLLPAHFWHCLCDLDSCSRMVPLFSRSYLAVWALSSLLVFLLMVAVYTRIFFFVRRRVERMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLDCKSCNVLAVEKYFLLLAEANSLVNAVVYSCRDAEMRRTFRRLLCCTCLRWSHHKSAHYS-------------------------SSARTGASTRIMLPENGHPLMDSTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL06-1", "uniprot_id": "LPAR2_MOUSE", "id": "Q9JL06-1", "name": "Lysophosphatidic acid receptor 2", "aln": "MGQCY---YNETIGFFYNNSGKELSLHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGMAYLFLMFHTGPRTARLSIKGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVTLIVGVWAAALGLGLLPAHFWHCLCDLDSCSRMVPLFSRSYLAAWALSSLLVFLLMVAVYTRIFFYVRRRVERMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLDCKSCNVLAVEKYFLLLAEANSLVNAVVYSCRDAEMRRTFRRLLCCMCLRWSSHKSARYS-------------------------ASAQTGASTRIMLPENGRPLMDSTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBW0-1", "uniprot_id": "LPAR2_HUMAN", "id": "Q9HBW0-1", "name": "Lysophosphatidic acid receptor 2", "aln": "MGQCY---YNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYT-------------------------SSAQGGASTRIMLPENGHPLMDSTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFF1-1", "uniprot_id": "F1QFF1_DANRE", "id": "F1QFF1-1", "name": "", "aln": "MVFNSCEAFDNPVSYFYNRTGKPISPNWRTHDFVVVGLGLPICVFIILANMLVIAAIIVNRKFHFPIYYLLGNMAAADLFAGISYSYLVFHTGPWTINLTIKEWFVRGALINMSLTASVVNLLAVAVERHQTIFTMQLHTTMTRRRVVMLIVTIWVVAVVMGLVPTMGWNCVCDQLGCSTVAPLYSRSFLVFWAILNLMAFFIMVAVYTHIFIYVRRRSQVMSPHTD-QPSNNQTVISLMKTMSMILGAFVICWTPGLVILLLDGLKCIECHVLKYEKYCLVLAECNSLVNPIIYSFRDEDMRTTYKRILCFPWRRMRPHEGPSGIRFEPVK-------------------TGAPPEKNSQNSSSPEAAPPQSPLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIF4-1", "uniprot_id": "A0A8M2BIF4_DANRE", "id": "A0A8M2BIF4-1", "name": "", "aln": "MVCYN----NETVVFFYSISHKNISDTWGTKAKAVVGMGLLVSVFVIFTNILVMAAIFMNRRFHYPIYYLLGNLAAADLFAGTSYMYLMFHTGPWTAKLTTYQWFVRQGLIDTSLTASVFNLMAIALERHQTIFTMQLHSKMTNHRVVLLILGIWTVAIIMGLVPAMGWNCMCDIGNCSTMAPLYSRSYLVFWAAINLLTFTVMVAVYTRIFIYVRRKSQRMSQHTS-QVKHKETVVNLMKTVVMILGCFVVCWTPGMVLLLLDGL-CHSCDVLTYEKFFLVLAESNSLMNPIIYSYRDKDMRDTFKRILCLCCRSKQSEE-HSGVRFNTLEQERRRRVQQESYLARRARDAGAQQENGGRLVLQENKEMLESSDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::.: :**. : * :* * .: .**.:** :.*:::::*:**:*** **:** ********:******** :* :*:***** * .*: **:* .*:: ****** .*:*:*:***::::::***: :.. *** **: :*..*: :**:*: *:*:* ** :.** ***:*. ** .*:.* :******:**::***: : *: *.. : .:*.:.*:**: :***.**:***** *:****** * .*.** **: *:***.***:*. :** ** :** *::*:** .: :.* . : : .. ", "identical_positions": 149, "similar_positions": 106, "identity": "39.63%" }, { "cls_id": "homologset.agr.HGNC:31682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNU9-1", "uniprot_id": "A0ABK0LNU9_RAT", "id": "A0ABK0LNU9-1", "name": "", "aln": "-------------------------------------------------------------------------MSSPSLSDLGKREPGAAGADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFILNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPTLQAIFYPVQGKEPSVRQLALLHFRNTITLSVKLEDALARSHACVPPAIAQMLLVLQGVHESRGVTEDYLRLETLIQKVVSPYLGTYGLYSNEGPCTHS-CILEKR-FLRRSRSGDILAKNPVVRSKSYNTPLLNPVAEHEAEGTASGGTSIRRHSVSEMTSCPEPQGFVDTPDQGPSG--------------------TFRSSPSPHSGPCPSRLYPPAHSPEQG--PDHGSPP--TSSPETLVDQILESVDSDSEGIFIDFGRGSRSSVSDFEAAGGRPSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q812A5-1", "uniprot_id": "PRR5_MOUSE", "id": "Q812A5-1", "name": "Proline-rich protein 5", "aln": "----------------------------------------------------------------MRTLRRLKFMSSPSLSDLGKREPGAAGTDERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFILNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPTLQAIFYPVQGKEPSVRQLALLHFRNTITLSVKLEDALARSHARVPPAIAQMLLVLQGVHESRGVTEDYLRLETLIQKVVSPYLGTYGLYSNEGPCTHS-CILEKR-FLRRSRSGDILAKNPVVRSKSYNTPLLNPVAEHEAEGTAASGTSIRRHSVSEMTSCPEPQGFVDTPGQGPSG--------------------TFRSSPTPHSGPCPSRLYPPAHSPEQG--PGHGSPS--TSSPETLVDQILESADSDSEGIFIDFGRGSRSSVSDFEAPGGRPSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P85299-1", "uniprot_id": "PRR5_HUMAN", "id": "P85299-1", "name": "Proline-rich protein 5", "aln": "----------------------------------------------------------------MRTLRRLKFMSSPSLSDLGKREP-AAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPMLQAIFYPVQGKEPSVRQLALLHFRNAITLSVKLEDALARAHARVPPAIVQMLLVLQGVHESRGVTEDYLRLETLVQKVVSPYLGTYGLHSSEGPFTHS-CILEKR-LLRRSRSGDVLAKNPVVRSKSYNTPLLNPVQEHEAEGAAAGGTSIRRHSVSEMTSCPEPQGFSDPPGQGPTG--------------------TFRSSPAPHSGPCPSRLYPTTQPPEQGLDPTRSSLP--RSSPENLVDQILESVDSDSEGIFIDFGRGRGSGMSDLEGSGGRQSVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YY64-1", "uniprot_id": "A0A8M6YY64_DANRE", "id": "A0A8M6YY64-1", "name": "", "aln": "MLIVSLSTSSNHTHTHTHTHTHTHTHTHTHRDRVEVKETALCFPSCSSLTAVRVLYCVCVCVCVMRTLHRLSLMSSPSLNDSGRSER-SALDDRNNQQQQRAGTNATWNSIHNAVISVFQRRDLAQNELYVLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFCDVLSTLQAIFYPVQGKEPSVRQLALLHFRNIITLNMKLEEALSRPRARIPPSITQMLLVLQGVHECKGVSGDYLKLEALLQRVVSPYLSTHGLYCSDGTLTHCCCVLEKRLLLHRPRGSPAPAKHPVVRSQSYNVPLLTPVAEYECESSTGASVCVRRHSVCQMTSCAE------EPVEVCED--------------------ELLPAPSPP------------LLPQRG--PRGAS-----YSPEPTAEQTLEAPDSDMEGIFIDFKRCSGS----PEDSEGGESVA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NZ01-1", "uniprot_id": "A0A8M1NZ01_DANRE", "id": "A0A8M1NZ01-1", "name": "", "aln": "----MKRGSGNLWITMLENLSGGHSDRPSSR-------SSSTFSFSSLFALPHHLHMDGSSHPFRRTLYRLKLVSSPNLSQLGKSEK-------ASLEERGSGPNATWNSIHNAVIAVFQKKGLADNELYTLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFCDVLTMLQAIFHPVQGKEPSVRQLALLHFRNTITLNMKLDEALSRPRARVPPSIVQMLLVLQGVHESKGVSEEYLKLESLLQKVVSPYLGTQGLCSHECGASHCSCFIERRLQYCWSKSADLPSTNPVVRSKSYNIPMLTPVAEYDSEVSSVGSVGIRRHSACDVTSCIEHQGYSALSVGIETSSTPRLSLDHDLMMRGAAGQPSLISPPVFIHTSTGCLHAPDAQIASSESEKVVSSPPSCSSSPETIVMQGLDSLESDPEGIFIDFSHCRSD----SFGTSRKTS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***.*.: *: * . ::: : .*********.**:***::.*.::**: *********************************************************.***. *****:******************* ***.:**::**:*.:* :**:*.***********.:**: :**:**:*:*:******.* ** . : :*. *.:*:* .:.. :.:*****:*** *:*.** *::.* :: ... :****..::*** * . . : ..* .. .* *** . * *:: :** ******* : . . * ", "identical_positions": 190, "similar_positions": 87, "identity": "39.83%" }, { "cls_id": "homologset.agr.HGNC:31684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TTC2-1", "uniprot_id": "TYY2_MOUSE", "id": "Q3TTC2-1", "name": "Transcription factor YY2", "aln": "MASETEKLLCLNTESAEIP-----------ADFVELLPPDNIGDIEAVSLETSVGQTIEVYGDVGVDWAHGS-QYHSPVIALQPLVG--------SSLSSRDHDKEMFVVQTRE--------EEVVGYQDSDNLLFSPEFGSQMVLP-VNEDDYLQPTTASFTGFLAAENG--QGELSPYEGNLCGLTTFIEAGAEESVN--ADLGDK---QWEQK--QIDGLDGEFPFT--------MWDDVNEKEDPIAEEQAGESP----------PDYS-------------------EYMTGKKFPPEGIPG-----IDLSDPKQ------LAEFTSMRPKKPK--GDF-----------PRPIACSHKGCEKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C6P6-1", "uniprot_id": "TYY2_RAT", "id": "P0C6P6-1", "name": "Transcription factor YY2", "aln": "MASDTEKLMCLTTENAEIP-----------ADFVELQPLD---EIETVSLETNVSQTIEVYGDVGVDWAHGG-HYHSPLIALQPLAG--------SNLSNGDHDQEMIIVQTR---------EEVVDYQDSDNLLLGTEFESQMVLP-VNEDDYLQPTTATFSGFMAAENG--QDELSPYGGNLCGLTTIIEAGAEEGVN--PDLGDK---QWEQKQIQIDGLDGEFPFA--------MWEDNNLKEDPVAEEEAGEST----------PDYS-------------------EYMTGKKFPPEGIPG-----IDLSDPKQ------LAEFTSMKPKKPK--GDF-----------PRPVACSHKGCGKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15391-1", "uniprot_id": "TYY2_HUMAN", "id": "O15391-1", "name": "Transcription factor YY2", "aln": "MASNED---FSITQDLEIP-----------ADIVELHDIN----VEPLPMEDIPTESVQ-YEDVDGNWIYGG-HNHPPLMVLQPLF---------TNTGYGDHDQEMLMLQTQ---------EEVVGYCDSDNQ-LGNDLEDQLALPDSIEDEHFQMTLASLSASAASTSTSTQSRSKKPSKKPSGKSATSTEANPAGSS--SSLGTR---KWEQKQMQVKTLEGEFSVT--------MWSPNDNNDQGAVGEGQAENP----------PDYS-------------------EYLKGKKLPPGGLPG-----IDLSDPKQ------LAEFTKVKPKRSK--GEP-----------PKTVPCSYSGCEKMFRDYAAMRKHLHIHGPRVHVCAECGKAFLESSKLRRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHLRIHTGDKPFVCPFDVCNRKFAQSTNLKTHILTHVKTKNNP---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8ST83-1", "uniprot_id": "PHO_DROME", "id": "Q8ST83-1", "name": "Polycomb protein PHO", "aln": "MAYERFGIILQSEQYDEDIGNTKVNQKMNEGNHYDLHRKN--AFDRIIHSESKKGDNVINYNIHENDKIKAADNIFSSKLKMNPNMSYEMNINCFKNIGYGENQETSKVLTNSLSNNDINTEESGVVDKNSPFLTLGTTILNSNGKSRRWEQKLVHIKTMEGEFSVTMWASGISDDEYSGSDQIVGASDLLKGKEEFGIDGFTSQQNKEYQKMESKFTNAQTLEMPHPISSVQIMDHLIKERGNLSQENNISERILSKTTLSFEEPILLPDSSSIELVNETAAMTINNHRTLSNHTGNTGDLHALPSSVPFRIGLHEGQVNDCLSTISQSTHQDNTDSTGCGEMNLSEVTVSYTNDKKIACPHKGCNKHFRDSSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDACNKKFAQSTNLKSHILTHAKAKRNTSISGKSGCSNAESNSQSEDTSANYVKVELQDSVTENHVPFVVYAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : : * .: :* : . : * :.: * : .. : ... : ::* .. . :::: :: . *. * :* :. : .. . *:. .: . : .. : * : . . .. : : *.* : . *: ...: : . : .:: * ... ** * . .*:. .:*. *.* : : ::: * . .. *: : :.*.:.** * *:* :******* ***************:*****:***********:********:***********:******:*******.**:*********:*****.* *.: ", "identical_positions": 119, "similar_positions": 109, "identity": "22.8%" }, { "cls_id": "homologset.agr.HGNC:31685", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYF7-1", "uniprot_id": "WASH1_RAT", "id": "B2RYF7-1", "name": "WASH complex subunit 1", "aln": "MTAVKTQHSLAGQVYAVPLIQPDLRREEAIQQVADALQYLQNISGDIFSRISQRVELSRRQLQAIGERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPEHLQEYNSVFTGALD-PGLQRRPRYRIQSKHRPLDERALQEKLKYFPVCVSTKSEPED---------EAEEGLGGLPSN-ISSISSLLLFNTTENLY----KKYVFLDPLAGAVTKTHTMLGTE-EEKLFDAPLSISKREQLEQPAPENYFYVPGLGQVPEIDVPSYLPDLPGVADDLMYSADLGPGIAPSAPG--AIPELPAFHTEVAEPFQPEREDGALLA---------PPPPPPPPPPPPPPAPTAVVSAPQ--PPMSPDVVTVTGKVAREEDSGSGEAHSASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGKGP-----GTGTSEGPGGAFSRMSDSIPPLPPPQQ------PAGDEDEDDWES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDD8-1", "uniprot_id": "WASH1_MOUSE", "id": "Q8VDD8-1", "name": "WASH complex subunit 1", "aln": "MTPVKTQCSLAGQLYAVPLIQPDLRREEAIQQVADALQYLQNISGDIFSRISRRVELSRRQLQAISERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPEHLQEYGSIFTGALD-PGLQRRPRYRIQSKHRPLDERALQEKLKYFPVCVNTKSEPED---------EAEEGLGGLPSN-ISSISSLLLFNTTENLY----KKYVFLDPLAGAVTKTHTMLGTE-EEKLFDAPLSISKREQLERQAPENYFYVPDLGQVPEIDVPSYLPDLPGVADDLMYSADLGPGIAPSAPG--AIPELPAFHTEVAEPLQPELENEVLLA---------APPPPPPPPPPPPPAPTALVSTPQ--PPMFPDMATAAGQVAREEDSSSSMAHTASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGKGP-----STGTSEGPGGAFSRMSDSIPPLPPPQQ------PAGDEDEEDWES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQA3-1", "uniprot_id": "WASH6_HUMAN", "id": "Q9NQA3-1", "name": "WAS protein family homolog 6", "aln": "------------MAFHEMQAHKNALGTSGEQQAADITGPTPHQGG------WKQVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQD-PGLQRRPRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPED---------DAEEGLGGLPSN-ISSVSSLLLFNTTENLY----KKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPSIANDLMYSADLGPGIAPSAPG--TIPELPTFHTEVAEPLKADLQDGVLT--------------PPPPPPPPPPAPEVLASAP----PLPPSTAAPVGQGARQDDGSSS--ASPSVQGAPREVVDPSGGWATLLESIRQAGGIGKAKLRSMKERKLEKKKQKEQEQVRATSQGGHLMSDLFNKLVMRRKGISGKGP-----GAG--EGPGGAFARVSDSIPPVPPPQQ------PQAEEDEDDWES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG59-1", "uniprot_id": "WASH1_DANRE", "id": "A4IG59-1", "name": "WASH complex subunit 1", "aln": "MVRMTQKRYLEGQVYSVPLIQPDLRREEAVHQITDALQYLEMISTDIFTRVSESVEKNRAHLQSVTDRIKLAQARVQKIKGSKKATKVFSSAKYPAPEKLQDYSSIFTGAVD-PASQKRPRIKVQSKLRPLDDKAQQEKLMYLPVCVNTKKRSED---------ETEEGLGSLPRN-VNSVSSLLLFNTTENLY----KKYVFLDPLAGAVTKTHTTLETEKEDKPFDAPLSITKREQLERQTAENYFYVPDLGQVPEIDVPSYLPDLPGIADDLMYSADLGPGFAPSVPASNSIPELPSFGTDHDESSGSDSQ---FKL---------EAPPPPPPPPPPPPEPTHVPVPPPGTSAAPPPPPPPPPMTADNTDASSPAPPTGTVKGAPSEVVQPSNGRASLLESIRNAGGIGKANLRNVKERKMEKKKQKEQEQVGATVSGGDLMSDLFNKLAMRRKGISGKGPAGQGDSSEAPASSGGAFARMSDVIPPLPAPQQ------SAAD-DEDDWEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JW27-1", "uniprot_id": "WASH1_DROME", "id": "Q7JW27-1", "name": "WASH complex subunit 1", "aln": "----MEESPYLHSPYQVAIIATDLHHEDTIIQAAQSLDCLHKTINSIFERIDARLARNGSKVEDINNRVKRAQAKIDALVGSKRAIQIFAPARFPASDVLAPLPATFPQVAANPLMEQQVDQLPQGTYSSHSAADQKPDDADIFFHVRGDREQESPLVAERKITNRTAGLGILPAGGVRSVPSLMRFNTNEFAYGEDLNAWKRSLPPQNARRVASQSTQLTGEKQLAPAPHSLAHGTTKLATPAGDLRYNPAALAAPAIDVPLDLPDLPGIANDLQYEPVEEQTPIAPSQQFGDLPELPDLGLEEQDIIVQAIAAQTHIPGPVRRKSVGQCPSPVTAAPPPPPPPPPPPPPPP---PAQTSAIPSPPPFPTKGAVKPLSPSLATPLNMPQPPPATEDPRSELMAAIRNAGGVHGGRLRSPAAAPLDVVDNSRSKAGGAVT--GDLMADLHNKLMLRRKGISGSQN------PVEATAGNPLMQQLSRVIPPPVQPRKGSKSSDEHSEDDEDGWN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * :: : . ::: : :::. ***::: : ***:* ::*:.*::**.: * : *. . * ::: *.. . . : . : . * . . *. : *** ** . : *:.**: ***.* * : : * .* : *.: ** *::: . : * * .* **** *****.:*:** *.. .. :**** : : : * ...***** * .* . . . . : . : . * ... : *: :**:***: ..**. :: .:...: *. *.**:**.*** :*******. . . . : ::* *** *:: .: **:.*: ", "identical_positions": 98, "similar_positions": 125, "identity": "19.03%" }, { "cls_id": "homologset.agr.HGNC:31686", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D9R7-1", "uniprot_id": "DMRTC_MOUSE", "id": "Q9D9R7-1", "name": "Doublesex- and mab-3-related transcription factor C1", "aln": "---------------------------MVEEEVAKKYDSSFTAG-------------------KNTVQQIQAQVDTATQEESSQGPVLLNQHPETTSVPYTPETVGQQLMVSLPGEPHGTSAMPSMCPSLILQPCATTDPMLLQPQVMGPSASNQASVS-ATLEWQEMLEAAEALLALKNSSQTR------HQPCGMPGTAGERGLQLA--------------------------NPSMPPRPTSSGSLPSGHLDCMSLLT--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QR87-1", "uniprot_id": "DMRTC_RAT", "id": "Q4QR87-1", "name": "Doublesex- and mab-3-related transcription factor C1", "aln": "-MQRPSGSREVRKAVSAVSASKKEQATRVKKHVVRRQKGTMAAAPKSHVHVKKLTVEEGVRTGKNSVHQLQAQVDTATQQESSQGPVLLSQLPETTSVPYTPETMGQQLTVSLSGEPYGPSAMPSMCPSLILQPCATTDPMLLQPQ--GSSASNQASVS-ATLEWQEMLEAAEALLALKNSSQTR------HQPCGMPGTAGERGLQLP--------------------------NPSMPPRPASSGSLPSGHLDCMSLLT--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HYR2-1", "uniprot_id": "DMRTC_HUMAN", "id": "Q5HYR2-1", "name": "Doublesex- and mab-3-related transcription factor C1", "aln": "------------------MAAPPKAPIRVRNLTIR--AGALTGK-------------------ENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLPCTPVTLEQQL-VSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQ--VPKVSDQALVS-AHSEWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPP--------------------------SPSLRPRPASSISLPIGHLGCISLLS--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GKM7-1", "uniprot_id": "A0A8I6GKM7_RAT", "id": "A0A8I6GKM7-1", "name": "", "aln": "MGNGTEEAPSTPPGPSASSTGSVQPPWALPQPLQRATISRLPAG-LGLAREQMSLRTMEPKDKPAVPCRPSTSEYNMGNRTAAALPVMEPRLRGHTSHAGRGHSCGSRIQVREQGEALLAVGSEKKGHSAPIKRRQIRLPRTTVPRKPLKQAKKTSTKGRGRTAKENPVSQPEDLLPKSPQEESAHGSQVHCWPSALPPLSEQQLMGPPPSVDLHGAFTLSNPYSNMIPVPCTSTDHHCPLEPQGSGASDQATIECQETLEAAEALMTLKNSSWNWHQSHR", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :.. : .: . :. :: .:: : * . : .:: * *:. . . . : :: * *: .... : . . :. :. .* **. . :: *. * : :: : . . .* .* : . : * . * ", "identical_positions": 14, "similar_positions": 62, "identity": "4.98%" }, { "cls_id": "homologset.agr.HGNC:31689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUY7-1", "uniprot_id": "F1LUY7_RAT", "id": "F1LUY7-1", "name": "mitogen-activated protein kinase kinase kinase", "aln": "MEGSGG----GGLAPAEAPEEAGESPQGRLPPGPEGAAGPAEPESAGDAAGG---ETEGGRGPRRALRAVYVRSESSQGAAAGGGPEAGALKCLLRACEAEGAHLTSVPFGELDFGETAVLDAFYDADVAIVDMSDISRQPSLFYHLGVRESFDMANNVILYYDTDADTALSLKDMVTQKNIAS--------------------------SGNYYFIPYTVTPCADYFCCESDAQRRASEYMQPNWDTILGPLCMPLVDRFTTLLKDIRVTSCAYYKETLLNDIRKAREKYQ--GDELAKELTRIKFRMDNIEVLTSDIIINLLLSYRDIQDYDAMVKLVETLKMLP-TCDLADQHNIKFHYAFALNRRNSTGDREKALQVMLQVLRSCDHPAPDMFCLCGRIYKDIFLDSGCEEDASRDSAIEWYRKGFELQSSLYSGINLAVLLIVSGQQFETSMELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFTVSMLASDIGKAVQAAERLFKLKPPVWYLRSLVQNLLLIQRFKKPITEHSP--RQERLNFWLDIIFEATN--EVTNGLRFPVLVIEPTKIYQPAYVSINNEAEERTVSLWHVSPTEMK----QIHEWNFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEEQCNRFCSLVKEMLNNGVGSTVELEGEADGDTLEYEYDHDVNGERVVLGKGSYGVVYAGRDLSNQVRIAIKEIPERDISAGDRTQVLEHARYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFLRQVNKGKKNRIAFKPSEGVRSG----TGTLALPSSGELMGSSSSEHGSISPDSDAQPDAFFEKVQVP------KPQLSH-LLSVPDESSALDDRSTALPPEERDPGLFLLRKDSERRAILYRILWEEQNQVASNLQECVVQSSEELLLSVGHIKQIIGILRDFIRSPEHRVMAATISKLKVDLDFDSSSINQIHLILFGFQDAVNRILRNHLIRPHWMFAMDNIIRRAVQAAVAILIPELQAHFEPASETEG---------VDKDTEMERDYPLVDL------LSQEVHVTTRGTRHGSV--------AIQEGQPHQQDPSLQLSKLRQETNRLWEHLVQKEREYQNLLRLILEQKTQELYHLQLQY-KCNGGTENPPP-----HDGLG---------TNRELIDWLQLQGVDANTIEKIVEEDYTLSDILNDITKEDLRCLRLRGGVLCRLWHAVSQHR------------------------------------------------RQMQESSQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AQW0-1", "uniprot_id": "M3K15_MOUSE", "id": "A2AQW0-1", "name": "Mitogen-activated protein kinase kinase kinase 15", "aln": "MEGGGGSGGGGGPVPAEAPEEAGEPPQGRLPPGPEGAAGLAEPESTGDAAGG---EAEGGRGPRRALRAVYVRSESSQGAAAGGGPEAGALKCLLRACEAEGAHLTSVPFGELDFGETAVLDAFYDADVAIVDMSDISRQPSLFYHLGVRESFDMANNVILYYDTDADTALSLKDMVTQKNTAS--------------------------SGNYYFIPYTVTPCADYFCCESDAQRRASEYMQPNWDTILGPLCMPLVDRFTSLLKDIRVTSCAYYKETLLNDIRKAREKYQ--GDELAKELTRIKFRMDNIEVLTSDIIINLLLSYRDIQDYDAMVKLVETLKMLP-TCDLADQHNIKFHYAFALNRRNSTGDREKALQVMLQVLQSCDHPAPDMFCLCGRIYKDIFLDSGCEEDASRDSAIEWYRKGFELQSSLYSGINLAVLLIVSGQQFETSMELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFTVSMLASDIGKAVQAAERLFKLKPPVWYLRSLVQNLLLIQRFKKPITEHSP--RQERLNFWLDIIFEATN--EVTNGLRFPVLVIEPTKVYQPSYVSINNEAEERTVSLWHVSPTEMK----QIHEWNFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEDQCNRFCSLVKEMLNNGVGSTVELEGEADGDTLEYEYDHDANGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDI------------RYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFLRQVNKGKKNRIAFKPSEGVRSG----TGTLALPSSGELVGSSSSEHGSISPDSDAQPDAFFEKVQVP------KHQLSH-LLSVPDESPALDDRSTALPPEERDPGLFLLRKDSERRAILYRILWEEQNQVASNLQECVVQSSEELLLSVSHIKQIIGILRDFIRSPEHRVMAATISKLKVDLDFDSSSINQIHLILFGFQDAVNRILRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELQAHFEPASETEG---------VDKDTEVEGDYPLVDL------LSQEVHVTPRGTRPGSV--------AIQEGQPHQQDPSLQLSKLRQETNRLWEHLVQKEREYQNLLRLILDQKTQELYHLQLQY-KSNGGTENPPP-----PDGLG---------TDRELIDWLQLQGVDANTIEKIVEEDYTLSDILNDITKEDLRCLRLRGGVLCRLWHAVSQHR------------------------------------------------RQMQESSQ-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZN16-1", "uniprot_id": "M3K15_HUMAN", "id": "Q6ZN16-1", "name": "Mitogen-activated protein kinase kinase kinase 15", "aln": "MESGGG------NAPAGALGAASESPQCPPPPGVEGAAGPAEPDGAAEGAAGGSGEGESGGGPRRALRAVYVRSESSQGGAAGG-PEAGARQCLLRACEAEGAHLTSVPFGELDFGETAVLDAFYDADVAVVDMSDVSRQPSLFYHLGVRESFDMANNVILYHDTDADTALSLKDMVTQKNTAS--------------------------SGNYYFIPYIVTPCADYFCCESDAQRRASEYMQPNWDNILGPLCMPLVDRFISLLKDIHVTSCVYYKETLLNDIRKAREKYQ--GEELAKELARIKLRMDNTEVLTSDIIINLLLSYRDIQDYDAMVKLVETLEMLP-TCDLADQHNIKFHYAFALNRRNSTGDREKALQIMLQVLQSCDHPGPDMFCLCGRIYKDIFLDSDCKDDTSRDSAIEWYRKGFELQSSLYSGINLAVLLIVAGQQFETSLELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFSVSMLAHDVGKAVQAAERLFKLKPPVWYLRSLVQNLLLIRRFKKTIIEHSP--RQERLNFWLDIIFEATN--EVTNGLRFPVLVIEPTKVYQPSYVSINNEAEERTVSLWHVSPTEMK----QMHEWNFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEEQCSRFFSLVKEMITNTAGSTVELEGETDGDTLEYEYDHDANGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDS------------RYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFLRQVNKGKKNRIAFKPSEGPRG------VVLALPTQGEPMATSSSEHGSVSPDSDAQPDALFERTRAP------RHHLGH-LLSVPDESSALEDRGLASSPEDRDQGLFLLRKDSERRAILYKILWEEQNQVASNLQECVAQSSEELHLSVGHIKQIIGILRDFIRSPEHRVMATTISKLKVDLDFDSSSISQIHLVLFGFQDAVNKILRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELRAHFEPTCETEG---------VDKDMDEAEEG------------------YPPATGPG------------QEAQPHQQHLSLQLGELRQETNRLLEHLVEKEREYQNLLRQTLEQKTQELYHLQLKL-KSNCITENPAG-----PYGQR---------TDKELIDWLRLQGADAKTIEKIVEEGYTLSDILNEITKEDLRYLRLRGGLLCRLWSAVSQYR------------------------------------------------RAQEASETKDKA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IRP8-1", "uniprot_id": "A0AC58IRP8_DANRE", "id": "A0AC58IRP8-1", "name": "mitogen-activated protein kinase kinase kinase", "aln": "MEIMSN----------LPTGEAG----GDHTNAVSMSAGMERADVTSPSPVS----------KQRSLRAVYVLNDGLKAVAANS-PESGALQCLQRACDAESAILTTVTFGRLDFGETTVLDTFYDADIAVVDMSDVFRQPSLFYHLGVRESFDMANNVILYHDMDPDTAQSLKDMVAQKNTAARPVKIGFPWVQLPPEYRGSGLRNKASSGNYYFIPYLMTPNNEYLCCENVAQRRASEYMQPNWDNLLGPLCVPLVDRFVSLLKDIHVTSCASYKDALLNDIRKARDKYQ--GEELAKELSRIKLRIDNTEVLTQDIVMNLLFSYRDIQDYDAMVKLVQTIEMLP-TCDLANQPMIQFHYAFALNRRNSPGDREQALRVMLQVLQSCEHPAPDMFCLCGRIYKDIFLDSDCKDTKNRDNAIQWYRKGFELQATLYSGINLAVLLIVAGQQFETSIELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFTVSMLANDIPKAVQAAEKLFKLKPPIWYLRSVVQNLQLIQHFKKQNTEHSP--QRERLNFWMDIIVEATQ--GTTNGLRFPVLILEPTKVYQPSYVSINSEAEEKNVSIWHVSPAETK----GIHEWNFTASSIKGISISKFDERCCFLYVHDNSDDFQIYFSTEDQCGRFCSMVKELITDGSGNAVELEGEGDGDTLEYEYDYNENGDRVVLGRGTYGVVYAGRDLSNQVRIAIKEIPERDS------------RYSQPLHEEIALHKYLKHRNIVQYLGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPLK--EATIIFYTRQILEGIRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSSEAKSFILSSFEPDPNKRAMAGDLLKDPFLRQNIKGKKNKIAFKPSVCLCVLDYIRSVSLPVQLQTEATGSSSSEPGSVSPDCDSKQDVFFEKKKRSSSENLIKPPSST-FLSVPDESPTAEDRSSPASSENSDSGLFLLKKDSERRAILYKVLNEDQDKVTSNLMENHIQGQEELKLSVDHIKQIICILRDFIRCPERRVMATTISKLKLDLDFDSTSINQIQLVLFGFQDSVNKVLRNHHIKPHWMFAMDNIIRRAVQAAVTILIPELQTHFGPASESEG---------ADKDADEVDEEDDADFGSVARTTQEDQVLTSGVSTLSSV--------ISHDAQRLQHPLGAQLGRLKQETCRLLEELVQKEREYQQVLRQTLQQRVHDIELIRIRQ-QPAAAEMPTTPSVFHVTAQPE---------PDKKLTDWLKEQGADSETIDKFVAEDYSLSDVLCDITKEDLRCLRLRGGMLCRIWKAIQQHRNKG--------------------------------------------LRKVKNDEGNSEG---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDS9-1", "uniprot_id": "Q9VDS9_DROME", "id": "Q9VDS9-1", "name": "", "aln": "------------------------------------------------------------------MDVVCVMDTAVGDHLEDR---QCALEEIKQAVQSAGANFQRVQFERLDFGETNVLETFYNADVAIIDLSILTQQRPLSYHYGVRESFGMKENILTYNDIDSKQTLSLK--------LS--------------------------CANYLFLSYKRN-AETNSCHLTSQPNSGNNSKEPNAEGRVP----TLQWRLKRKLQDVEIQSKAHMREKFLSDMRTARDTYATNGAKLQSILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLVNDLKNIPNTRKYVETGNMSFLYAFALNRRNRKGDREKALESSLKALEKKENHFPDMLCLCGRIYKDIFVESDYTDATSLAHAIKWYRQSFEVQPNEYAGINLATLLVIEGKEFTNTEELQHIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLANDYAKAIQAAECMFKLKPPNWYLKSTIGNISLIHRFRKKPEERQPPIEEQVFQFWMDFFLEATNTEEVKNSIRFPILILEPQKIYMPSYVTINMDADEKSIQIVNICLAHAKNACKKIHDFLFVASKIKSVSLYKRDDRCAYLYVHHNSDDFQIYFPSTERRQKFYDMILEMTAD---QVVFVNLSNDDANIEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNS------------QDVQPLHEEIKLHSQLRHRNIVRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFLQDKPRKVRPALPINTEFGRSIS---VPADRFVHKTTPPLSYNTTCNTPTTPELDITHSSSVDIDELPSNQFMLERRNSHGFLLSPEIEPSTPSLRTSISETSETDGFYRLKKDSQRRTTLSKVLALDESKICDIWLKKVDADQNSIAIRKSDLEVLIRGLRDYIMNENEKHLEATINELKQKLNNDAVALDHLHLALYSFQDAVVCVLRYHCIKPHWMFALDNLVKRAVQAAVTIFSPELGANLADKDLSGNDDESLRTSLMQKGSTESQEKQSLEKVLPTSNTREGVGLTPAESGGDALSSSMECARILRDIRDNQQKLQRQLLEQQRQSMRALHNISQELAHIYMGGRKRLRRTINGFNKKCHRMSTSVGGTSGVRPNIAGNPRRQLNKHHFGLHEVDEQLEQWLTQQEIDEFSKTLILNEGFTFDDFIYNMEKLDLMRLGLRVGIEVRLWKLIIQERVCTSSDCVDSPPSTYHKPIGGNSSFALIDNNNTLPSPTTTTPGTPGIKTKIKKSESEYDSCSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* * . . . * : : :* :: .* : * * .****** **::**:**:*::*:* : :* .* ** ******.* :*:: * * *.. : *** : ..** *:.* . * . . ..: :** : : .* *: *:*:.: * . :: :*.*:*.**:.* * :* . * .:: *:*: .**: ::: .:: * **:*******:**: :: :* * . .: :.* ********* ****:**. *:.*.. :: ***:***********::*. : . **:***:.**:*.. *:*****.**:: *::* .: **::**: **.*:*:****..:.:****. ** :*:** * **:**** :****** ***:* : *: **::*:* *:.* ..: ::**:*::.***: ..*.:***:*::** *:* *:**:** :*:*:.:.: ::. :. * :*:: *.**.**.:*: * *:**.:****.*********.: :: :* .:: *: : ..* :: . *. .:*****:: :. ::***:*:** ***.** ..********:**:: : ******* **. *:*****:**** **:*::************* **.:****:* *.*: **::*****::****::*******************:************ :** **************:**:* ****..*****:*** :****.:*** ***..:*******::* **:*** **::*: *** .* . .* :.:**.: **:: : : :.::.. : . .:: . :*: * . .: . . . . :* *: ..: . . . . *:: *:***:**: * ::* ::.:: . : ..:.: : ..:: :* ***:* :.: : :**.:** .*: *: ::.:::* *:.***:* :** * *:******:**:::*******:*: *** ::: : . :*. : . : . :: : *: ** . :::: * ..: :: . * * : : : : :.:* :** * * : :: *.:::.*.: :: * ** * ** *: *:* : * * : .. ", "identical_positions": 482, "similar_positions": 397, "identity": "32.37%" }, { "cls_id": "homologset.agr.HGNC:3169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47752-1", "uniprot_id": "S1PR2_RAT", "id": "P47752-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "--------------MGGLYSEYLNPEKVQEHYNYTKETLDMQETP---SRKVASAF---IIILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGPVTLSLTPLQWFAREGSAFITLSASVFSLLAIAIERQVAIAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLDHLEACSTVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLGVFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVLRPLLCWRQGKGATGRR-GGNPGHRLLPLRSSSSLERG---LHMPTSPTFLEGNTVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52592-1", "uniprot_id": "S1PR2_MOUSE", "id": "P52592-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "--------------MGGLYSEYLNPEKVLEHYNYTKETLDMQETT---SRKVASAF---IIILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGHVTLSLTPVQWFAREGSAFITLSASVFSLLAIAIERQVALAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLNQLEACSTVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLGVFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVLRPLQCWRRGKGVTGRR-GGNPGHRLLPLRSSSSLERG---MHMPTSPTFLEGNTVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95136-1", "uniprot_id": "S1PR2_HUMAN", "id": "O95136-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "--------------MGSLYSEYLNPNKVQEHYNYTKETLETQETT---SRQVASAF---IVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERG---MHMPTSPTFLEGNTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8K8-1", "uniprot_id": "S1PR2_DANRE", "id": "Q9I8K8-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "MTTCRLFAGFCQAVTMSKYSQYFNKTLIQVHYLTAKEMTAEELRDRIESKQSLSSLNILFVVICSIIILENLLVLIAVFRNKKFHSAMFFFIGNLAFSDLLAGSAYIANIFLSGPRTFHLTPVQWFIREGTAFIALSASVFSLLAIAIERYIAITKVKVYGSNKTCRMFLLIGACWVMSILLGGLPIIGWNCINNLDDCSAVLPLNTRYYIRFVVTIFSIILLSIVILYVRIYLIVRTSHQEATNSPAYALLKTVTIVLGVFIICWLPAFTILLLDTSCKMKQCPILNNAGIFFSFATLNSALNPLIYTLRSKDMRKEFLRVLCCW--GLLNCGRP----PHRCMVPLKSSSSMEHCTNKHEHQSIPIMQDCTTCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:*:* : ** :** : *:: *:: ::::*. *::********* **.******::*:**** ****** *::** :*** *: ***:*** ***:***:*************** :*::***:***:*:***::****.*::*::******:****:.:*: **:**** :::*: ******:***:** ****** :**:** : : . : **************:******:***** :* :: **:* :* **:.:**** ***:*** **:*:*:*.** * ** * ** * : ::**:****:*: . : * : : .* *", "identical_positions": 196, "similar_positions": 85, "identity": "52.13%" }, { "cls_id": "homologset.agr.HGNC:31690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC88-1", "uniprot_id": "CR032_RAT", "id": "B1WC88-1", "name": "UPF0729 protein C18orf32 homolog", "aln": "MVCIPCIVIPVLLWIFKKFLEPYIYPVVS----RIWPRKAVQQLDNKNTGK---VDCKG---------------ADTNGFSTKGP----------TEVSDKKKD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WE4-1", "uniprot_id": "CR032_MOUSE", "id": "Q91WE4-1", "name": "UPF0729 protein C18orf32 homolog", "aln": "MVCIPCIVIPVLLWIFKKFLEPYIYPVVS----RIWPKKAVQQSGDKNMSK---VDCKG---------------AGTNGLPTKGP----------TEVSDKKKD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCD1-1", "uniprot_id": "CR032_HUMAN", "id": "Q8TCD1-1", "name": "UPF0729 protein C18orf32", "aln": "MVCIPCIVIPVLLWIYKKFLEPYIYPLVSPFVSRIWPKKAIQESNDTNKGK---VNFKG---------------ADMNGLPTKGP----------TEICDKKKD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97172-1", "uniprot_id": "U729_DROME", "id": "O97172-1", "name": "UPF0729 protein CG18508", "aln": "MVCVPCIIIPLLLYIWHKFVQPILLRYWN-----PWEKKD-DDGNVIKKGPDFPFECKGGVCPFVPGGKKTENVSDDDAEESENPPLNATAMAAETEVDESKKEI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***:**:**:*::**::* : . * :* :: . : . .: ** :. :. ::.* **: :.**: ", "identical_positions": 23, "similar_positions": 29, "identity": "21.9%" }, { "cls_id": "homologset.agr.HGNC:31696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZSG1-1", "uniprot_id": "ARK2C_HUMAN", "id": "Q6ZSG1-1", "name": "E3 ubiquitin-protein ligase ARK2C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRNR----------GAPFQRSQHPHATSCRHFH----------------LGPPQPQQLAPDFPLAHPVQSQPGLSAHMAPAHQHSGALHQSLTPLPTLQFQDVTGPSFLP---QALHQQYLLQQQLLEAQHRRLVSHP-------------------------------------------------RRSQERVSVHPHRLHPSFDFG-QLQTP--------------------------------QPRYLAEGTDWDLSVDAGLSPAQFQVRPIP------------------QHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVR-------------------ESYEELLQLEDRLG-------------NVTRGAVQNTIERFTFPHKYKKRRPQDGKGKKDEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QAU8-1", "uniprot_id": "ARK2C_MOUSE", "id": "E9QAU8-1", "name": "E3 ubiquitin-protein ligase ARK2C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRNR----------GAPFQRSQHPHATSCRHFH----------------LGPPQPQQLAPDFPLAHPVQSQPGLSAHMAPAHQHSGTLHQSLTPLPTLQFQDVTGPSFLP---QALHQQYLLQQQLLEAQHRRLVSHP-------------------------------------------------RRNQDRVSVHPHRLHPSFDFGHQLQTP--------------------------------QPRYLAEGTDWDLSVDAGLSPAQFQVRPIP------------------QHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVR-------------------ESYEELLQLEDRLG-------------NVTRGAVQNTIERFTFPHKYKKRRPQDSKGKKDEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BE56-1", "uniprot_id": "A0A8M2BE56_DANRE", "id": "A0A8M2BE56-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRNR----------GSHFNRHQHSHATSCRHFH----------------VGP--QAQIPVDFPMPHPGQSQTGMSHHLGPAHQPTAALHPSLNHIPAPPFQDIPAPPFLP---QALHQQYLIQQQILEAQHRRILPQPS------------------------------------------------RHAPDRTLPHPQTLRPPYEYPPSIHIPP---------------------------PVPQQPRYLAEGTDWDLSVDPGLP--QYHISPLT------------------QHYQHYLTSPRLHHFPRNTTSAQVVVHEIRNYPYPQLHLLALQSLSPSRHATAVR-------------------ESYEELLQLEDRLG-------------NVNRGAVQATIERFTFPHKYKKRRPLELKIGMDE-EELDTDEKCTICLSMLEDEEDVRRLPCMHLFHQACVDQWLATNKKCPICRVDIETQLSPDS--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YUK5-1", "uniprot_id": "A0A8M6YUK5_DANRE", "id": "A0A8M6YUK5-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRSRGCMDSLSSRTGAHFSRHQHSHATSCRHFH----------------LAAT-ATPLPADFPPP----------------------------PLAPPQYQEVP-PPFLP---QALQQQYLIQQQLLQR----------------------------------------------------------RRTQERVPLNTHRLRPGYEYAPPLHVPQ---------------------------PIPQQPRYLAEGTDWDLSVDAGVLH-QYPLQQIP------------------QPYQHYLASPRMHHLPRNTSTTQVVVHEIRNYPYPQLHLLALQSLSPSRHSSAVR-------------------ESYEELLQLEDRLG-------------SVSRGAIQTTIERFTFPHKYKKRKPLDLKFCEND-EESDVDEKCTICLSMLEDGEDVRRLPCMHLFHQACVDQWLATSRKCPICRVDIQTQLSPES--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFN6-1", "uniprot_id": "A0A0B4KFN6_DROME", "id": "A0A0B4KFN6-1", "name": "RING-type domain-containing protein", "aln": "MDSLENDQEELHHQPRVTLAYGSVATSSGGQENHSQYAMYYNQQRDSEGYMLMTPFLSSSQSHSHTRSPPTYTAMVEPRREESSGFEGLARRCDKCSSLDGLCRCESMVASSSRYADSTQNQSHSEAQFLEQPSSSTAAIANPPAVHSIPRPKRKKTEPLTMEPESDNDGDAVVASVSGTWPAGAIEEHAMDSTAVVYEVPSSSLQLSNSSFETAPSAVNAYDDVTSSASDTEHGQFAHTRTTNTTTTTSAVQAHKKKASRSNNASNTSSRAVDTDATPSTSAQSRKRQMSQFSYRKSRVLEPENESSDDGWDLRVHNPVPPIEPTVTIIRGSRGSDEAEIGHTDHNYYNSRCAVAGAPPDSTYIRSASCSTATHTTRSVDYGSRIGRRSAATGSPSTSSDQEQEQQQRQQQEEIIHEERRHQQSPGQPMHSMYGVPGESRMSWSRARPSDDSVPPRKHARMELPGRSRSKLSSTNFNSFYPGRRGHRTFAEQGNSSGQHHVRFPPSSTPNSNGPCVITYVGRPRDSQPAADLNLPSTSTGRRGSHETRADSVVLTAPDLQLDDWSSDDDDDDVVFVHSTREPILSIDLTSDDDGLANDTQLQRDRDRGRERERERARDREPYRNDTQPNPEDPNEDRRTMYDCAYTFPYARRTDRRTEANNEGTSAFAFYSGALADRAAISDHNYSYELDQLMDPGPGNFYPPRCSNMDPQRYFLPINESSMWMPGHPAPPPPPPPMPPILLPDNSSTEAYLRHQQRNLTSTPSSSSSEQTSTQQSRHRRSSPANVYHRYHPYYYAITTLPTVVESDYPPSLQPHPHPHPHFQPSQGGSSRSSLSGALNAAAVAATAAAVQAQTFSDLLSQAHNEGRAAALEGNRTPPHTMVHAQHQQRQSINPPAPGVASNANLAAAVSPPPPLEMYSGRSTIPHCGSPPFSVRRSEAAYSNRQHYQPQPHQGHQAPQNQMHAHIHPPHRASAIVATSLTPAPPYPVHQNLWYRQQSMQEMHRRHMTPTPIDLSSNAPLLTSTLRNGYLHSICSCVHARNGPVSSLDPAYYPPYDAAPAAAAPPPSPQQQSPATSGSGNSSVAAQASMRHLQLQPQQQPQAQQSPPVMQHMQRQRAIHHHMFHHHYSPLHLEIGLAPLSLGSRILIAPSRPNRGATLETIERNTLPHKYRRVRRPS--------ETDEDAEKCAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPICRVDIETHMPNDALPPSSSGVPDAANSAALXHCVHGIFM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* . . : . *. : .: :* :::... :* . . .* . : . :.:: .. **. : : ::. .: : : * : :: * * * *** :. : : * * ::* * .. . .. * . . : *.*.::. * : . : . *:** *. .*** **** *:****:: : . * : ***:***.::* ::*********** ******. .::********:*:: :: ", "identical_positions": 72, "similar_positions": 90, "identity": "5.66%" }, { "cls_id": "homologset.agr.HGNC:317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02772-1", "uniprot_id": "FETA_MOUSE", "id": "P02772-1", "name": "Alpha-fetoprotein", "aln": "------MKWITPASLILLLHFAASKALHENEFGIASTLDSSQCVTEKNVLSIATITFTQFVPEATEEEVNKMTSDVLAAMKKNSGD----GCLESQLSVFLDEICHETELSNKYGLSGCCSQSGVERHQCLLARKKTAPASVPPFQFPEPAESCKAHEENRAVFMNRFIYEVSRRNPFMYAPAILSLAAQYDKVVLACCKADNKEECFQTKRASIAKELREGSMLNEHVCSVIRKFGSRNLQATTIIKLSQKLTEANFTEIQKLALDVAHIHEECCQGNSLECLQDGEKVMTYICSQQNILSSKIAECCKLPMIQLGFCIIHAENGVKPEGLSLNPSQFLGDRNFAQFSSEEKIMFMASFLHEYSRTHPNLPVSVILRIAKTYQEILEKCSQSGNLPGCQDNLEEELQKHIEESQALSKQSCALYQTLGDYKLQNLFLIGYTRKAPQLTSAELIDLTGKMVSIASTCCQLSEEKWSGCGEGMADIFIGHLCIRNEASPVNSGISHCCNSSYSNRRLCITSFLRDETYAPPPFSEDKFIFHKDLCQAQGKALQTMKQELLINLVKQKPELTEEQLAAVTADFSGLLEKCCKAQDQEVCFTEEGPKLISKTRDALGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02773-1", "uniprot_id": "FETA_RAT", "id": "P02773-1", "name": "Alpha-fetoprotein", "aln": "MKQPATMKWSASISFLLLLNFAEPRVLHTNEFGIESTLDSSQCPTEKNMFNVATIVVAQFVQDATKAEVNKMSSDALAAMKENTGD----GCLENQLSVFLDEICHETELSNKYGFSGCCNQSGVERHQCLLARKKTAPDSVPPFHFPETAESCPAYEENRAMSINTFIYDVSKRNPFLYAPTILYLAAQYDKAVPACCKADNMEECFQTKRASMAKELREGSMLNEHVCAVIRKFGSRNLQAVLIIKLSQKFPKANITEIRKLALDVAHIHEQCCHGNAMECLQDGESVMTHMCSQQEILSSKTAECCKLPTIELGYCIIHAENGDKPEGLTLNPSEFLGDRNFAQFSSEEKLLFMASFLHEYSRNHPNLPVSVILKTAKSYQEILEKCSQSETPSKCQDNMEEELQKHIQESQALAKQSCNLYQKLGPYYLQNLFLIGYTRKAPQLTSAELIDLTGKMVSIASTCCQLSEEKRSACGEGLADIYIGHLCLRHEANPVNSGINHCCSSSYSNRRLCITSFLRDETYVPPPFSEDKFIFHKDLCQAQGRALQTMKQELLINLVKQKPEMTEEQHAAVTADFSGLLEKCCKDQDQEACFAKEGPKLISKTREALGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02771-1", "uniprot_id": "FETA_HUMAN", "id": "P02771-1", "name": "Alpha-fetoprotein", "aln": "------MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLISKTRAALGV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** . :::**:*: .:.** **:** * *** ** :* .: .:*** .:*** :** **.** .*.*:*::: :** ****.**..**:*:***.*: :*** *.**.** **:*:**:**.:* *:* *:.**.. ** *:**:* :* ***::::*:**:***:** **:*** : :****:* ****** *:::*****.*:**:*.*:*:::**:*.:** : *****:.:.*:***:**.*****:**.**:*: ::******.:*:::****: **.* :*****. :: * *******. *****: * ..*****:* **** ** :*:***:***** **:*.*****: ** ***:**** *: . ***: ******:*:*****:*:** *:*.** * *** **:.**:*******:**: :* **.: *:*******:* .**** *** *****:*:* .***.*:.:**.***:*** *::*:: ****.**.**:************** ********:*********::**** ** ***********: *:**.**::** ******* ****", "identical_positions": 367, "similar_positions": 155, "identity": "59.67%" }, { "cls_id": "homologset.agr.HGNC:3170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEH8-1", "uniprot_id": "D4AEH8_RAT", "id": "D4AEH8-1", "name": "Sphingosine 1-phosphate receptor 4", "aln": "MNISTWSTLVTPESCHRLAASGHSLLIVLHYNHSGRLASRGGPEDNGGLGMLRGPSVAAGCLVVLENAMVLAAIAIHMRSR-RWVYYCLLNITLSDLLTGLAYVVNVLLSGTRTFQLSPVHWFLREGLLFMALAASTFSLLFTAGERFATMVR-VAESGATKTSRVYGCIGLCWLLAATLGLLPLLGWNCVCAFQRCSSLLPLYSKGYVLFCVVVFALILVTILSLYGAIFRVVRANGQKSPRPPARRKSRRLLNTVLMILVAFVVCWGPLFGLLLADIFGSNVWAQEYLRGMDWILALAVLNSAINPLIYSFRSREVQHAVLTFLCCGCLRLGLRGPGDCLTRITEAHSGASTTDSSLRPRDSFRTSRSLSFK--------MREPLSSVSSIRSA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0L1-1", "uniprot_id": "S1PR4_MOUSE", "id": "Q9Z0L1-1", "name": "Sphingosine 1-phosphate receptor 4", "aln": "MNISTWSTLVTPESCHRLAASGHSLLIVLHYNHSGRLASRGGSEDGGGLGMLRGPSVAAGCLVVLENAMVLAAIAIYMRSR-RWVYYCLLNITLSDLLTGLAYVVNVLLSGTRTFQLSPVHWFLREGLLFMALAASTFSLLFTAGERFATMVR-VAESGATKTSRVYGCIGLCWLLAAILGLLPLLGWNCVCAFPRCSSLLPLYSKGYVLFCVVVFALILVAILSLYGAIFRVVRANGQKSPRPPARRKSRRLLNTVLMILVAFVVCWGPLFGLLLADIFGSNVWAQEYLRGMDWILALAVFNSAINPLIYSFRSREVQRAVLAFLCCGCLWLGLRGPGDCLTRITEAHSGASTTDSSLRPRDSFRTSRSLSFR--------MREPLSSISSVRST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95977-1", "uniprot_id": "S1PR4_HUMAN", "id": "O95977-1", "name": "Sphingosine 1-phosphate receptor 4", "aln": "MNAT--GTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPED-GGLGALRGLSVAASCLVVLENLLVLAAITSHMRSR-RWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFR--------MREPLSSISSVRSI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC10-1", "uniprot_id": "F1QC10_DANRE", "id": "F1QC10-1", "name": "", "aln": "MEVLR--SFSSASSCPDVYNWTSNSLILEHYNYTGRLHHRKPSKK--SVSAVTVLFLCFSVFIILENLMVLLAVLFRVRLRHRWIFICIANIALSDLLTGTSYVVNICMSGEQTFRLTPILWLFREGLLFVALAASIFSLLLIAVERYATMMKPVHQKTATKTYRVYIMMLLCWITAFIIGFLPLMGWNCVCDLRSCSTLLPLYSKSYILFALVIFFIILLTIGVLYFAIYCHVRSS-TETISARSRKRSLRLLKAVISIVGVFMVCWGPLFILLLVDFFCYSRSCSPLFN-PEWVIALAVLNSAMNPLIYSFGSLELRKAIATLLCCSCLKAGLCDPKTFMSKETSSTSGS--RHSSLR--NSFSKVRNLSTSPPPEPKNGKKTRLSSTTSCLSASSG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : :..** : . **: ***::*** * .:. .:. : :. . :::*** :** *: :* * **:: *: **:******* :*:.*: :** :**:*:* *::****** ***** ****: * **:***:: * :. **** *** : ***: * :*:***:****:* : **:******* *:**.:*:* :* :* ** **: *::. :: . :*::: ***::*: *: .*:******* ***.*.* . .. :. :*::****:***:**:**** * *: :*: ::***.** *: .* ::: ..: **: .**** :** *.** : *** :* * ", "identical_positions": 163, "similar_positions": 110, "identity": "40.85%" }, { "cls_id": "homologset.agr.HGNC:31700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCZ7-1", "uniprot_id": "ZBT7C_MOUSE", "id": "Q8VCZ7-1", "name": "Zinc finger and BTB domain-containing protein 7C", "aln": "MANDIDELIGIPFPNHSSEVLCSLNEQRHAGLLCDVLLVVQEQEYRTHRSVLAACSKYFKKLFTAGSLASQPYVYEIDFVQPEALAAILEFAYTSTLTITASNVKHILNAARMLEIQCIVNVCLEIMEPGGSVGEEDDKEEEDEDDDDEDEDDEEEEEEEEEEEEDDPEDFADQENLPDPQDITCPQSPSKTDHLTEKDYSDTPRDFPDSFQPGSPGHLGVIRDFSIESLLRENLYPKANIPDRRPSLSPFAPEFFPHLWPGGFGAFAQLPEQPMDSGPLDLVIKNRKIKEEDKEELAPPPPPPFSSDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGSLFPPWPLVEERKLKPKASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCSICEVRFTRQDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRGRKPAAWRAASLLFGPGGPSADKAAFVMPPALGDVGGHLGGTAVCLPGPSPAKHFLASPKGTLSLQELERQFEETQMKLFGRAQLEAERNAGGLLALALAENVAATRPYFPLPDPWAAGLAGLPGLTGLNHVASMSEANN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1YPR0-1", "uniprot_id": "ZBT7C_HUMAN", "id": "A1YPR0-1", "name": "Zinc finger and BTB domain-containing protein 7C", "aln": "MANDIDELIGIPFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFKKLFTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIVNVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQSPSKTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLRENLYPKANIPDRRPSLSPFAPDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKIKEEEKEELPPPPPPPFPNDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKPKASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRGRKPAAWRAASLLFGPGGPAPDKAAFVMPPALGEVGGHLGGAAVCLPGPSPAKHFLAAPKGALSLQELERQFEETQMKLFGRAQLEAERNAGGLLAFALAENVAAARPYFPLPDPWAAGLAGLPGLAGLNHVASMSEANN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************** ************************************:**********************************.*****************************. *******::*:*:**:**:**********:::**.***************:* ************ *************.****************************************:********.*****************************:****.*******..*************************************.*************************************************:*******************************************************************************************************:.************:*******:***************:***:**********************************:********:********************:*************", "identical_positions": 583, "similar_positions": 32, "identity": "94.18%" }, { "cls_id": "homologset.agr.HGNC:31702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32ZH7-1", "uniprot_id": "DFB14_RAT", "id": "Q32ZH7-1", "name": "Beta-defensin 14", "aln": "MRLHYLLFVFLILFLVPAPGDTFIPKSLRRFFCRVRGGRCAILNCLGKEEQIGRCSNRGQKCCRKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNV9-1", "uniprot_id": "DFB14_MOUSE", "id": "Q7TNV9-1", "name": "Beta-defensin 14", "aln": "MRLHYLLFVFLILFLVPAPGDAFLPKTLRKFFCRIRGGRCAVLNCLGKEEQIGRCSNSGRKCCRKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81534-1", "uniprot_id": "D103A_HUMAN", "id": "P81534-1", "name": "Beta-defensin 103", "aln": "MRIHYLLFALLFLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****.:*:*****.**. : ::*::::**:******:*.** ******:**. *:****:**", "identical_positions": 42, "similar_positions": 20, "identity": "62.69%" }, { "cls_id": "homologset.agr.HGNC:31703", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BJ52-1", "uniprot_id": "PLPR5_MOUSE", "id": "Q8BJ52-1", "name": "Phospholipid phosphatase-related protein type 5", "aln": "MPLLPVALISSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAATYLTMYITSTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQPENGHIHRDNVARMPMTNIPRVESPLEKVTS---------LQNHVTAFAEVT-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32ZL2-1", "uniprot_id": "PLPR5_HUMAN", "id": "Q32ZL2-1", "name": "Phospholipid phosphatase-related protein type 5", "aln": "MPLLPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQAENEHIHMDNLAQMPMISIPRVESPLEKVTS---------VQNHITAFAEVT-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6B5V9-1", "uniprot_id": "A0A8I6B5V9_RAT", "id": "A0A8I6B5V9-1", "name": "Phospholipid phosphatase-related protein type 5", "aln": "MPLLPAALISSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQPENGHLHRDNVARMPMTNIPRVESPLEKVFQNQYMEDDQEENSQGTSFKDCLARLFGWILGISHCEHLQTTSLPLQKSHDIEADGFSLHWTSSLFTIHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5WUN8-1", "uniprot_id": "A5WUN8_DANRE", "id": "A5WUN8-1", "name": "Phospholipid phosphatase-related protein type 5", "aln": "-----------MLYFQLVIMAGTVMLAYYFEYTDTFNVHVQGFFCHDNAYTKPYLGPEESSAIPPAILYAVVAGVPALVITVTESVLFLLQYVSEDLDNREKIIVMGDCCYLNPLVRRTFRFLGVYAFGLFATDIFVNAGQVVTGNLSPYFLTVCKPNYTALGCQQVVRFINQQDACTGNEDDILHARKSFPSKEAAISVYAALYVAMYITCSVKAKGTRLAKPVLSLGLMCLAFLTGINRVVEYRNHWADVIAGFIIGGAIAVFMVVCVVKNFKGKPLLSEIPPEESVSSGPMITQPRLDHTMEKYIA----------SQNPITYAEIT-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:*******************.*:********.** *** ***:***:**.:**::.****.*** * *:.:* ** .:.*::*:** *: *****:*******.****:*:********************:*:**::************ .:**. ::***** * *::***:*******:***** *::**** ::************.***********:***.******:******::* :****:*****:****: . :.:: ** . **:: .:** ..: :: : ", "identical_positions": 204, "similar_positions": 69, "identity": "54.11%" }, { "cls_id": "homologset.agr.HGNC:31704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VWR6-1", "uniprot_id": "Q9VWR6_DROME", "id": "Q9VWR6-1", "name": "Metalloendopeptidase", "aln": "---------------------------------MPRSALIVPGLICFWSALALALSATLEASTPATRKALLRARPAVPPAARWGANMQMLRRHNSPAFNFWTEDSD-----TNIWEHCGLFEGDIMLHRELLRNGLLNERLTWPEAAVPF------YIDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQGDKHWLLIKGN---YSGCWSSVGRRSGGQVLNLN----TPKCVTHG--VVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKN-GKATIEPLD-P--YASLGQRRGLSDKDVSKLNEMYEQDCSEDYLLNFDRFGNYIDELLDYFQGNIQDLLG----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3R0-1", "uniprot_id": "Q9V3R0_DROME", "id": "Q9V3R0-1", "name": "Metalloendopeptidase", "aln": "-------------------------------------------MIRVW--FQLFLLGTLCS--------------GIFPAP------------------FNTHYDE-----TDPELTAGYFQGDMDVD--YARNGQLSETRRWPNATVPY------RIS-EEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPS---TSGCSSKVGYQPGERTVKLKPGSLDTGCFKLG--TIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSIN-GEATIVALN-PEGQEQMGQRLMMSDTDVKRLNTMYK--CPIQL-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZX09-1", "uniprot_id": "D3ZX09_RAT", "id": "D3ZX09-1", "name": "Metalloendopeptidase", "aln": "--------------------------------------MGGVGSLGSLWPWMLTLLSLTGLILGAPSASRCSGVCSTSVPEGFTPEGSRVSQDKDIPAINQGLISE-----ETP-ESSFLVEGDIIRPSPFRLLSVTNN--KWPKGVDGI--VEIPFLLSSKYDEPSRQVIMEAFAEFERFTCIRFVAY-RGQRDFVSILP----MAGCFSGVGRSGGMQVVSLAPT-----CLQKGRGIVLHELMHVLGFWHEHSRADRDRYIRVNWNEILPGFEINFIKSRNSNML---APYDYSSVMHYGRFAFSWR-GQPTIIPL--WTSSVHIGQRWNLSTSDITRVCRLYS--CSPSVPDSHGRGFEAPSDGRSPTPASISHLQRLLEALSEESRSSAPSGSGTGGQGIIAGFVDSQQGWEHPAQSTFSVGALARSPQMLAAASKSRPGAGADSISLEQFQPAQAPAVPPVSFPDARDKPTPIQDAFARLALLPGGCAPGSHIREVPRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6HA09-1", "uniprot_id": "ASTL_MOUSE", "id": "Q6HA09-1", "name": "Astacin-like metalloendopeptidase", "aln": "-----------------------------------------MGIMGSLWPWILTMLSLLGLSMGAPSASRCSGVCSTSVPEGFTPEGSPVFQDKDIPAINQGLISE-----ETP-ESSFLVEGDIIRPSPFRLLSVTNN--KWPKGVGGF--VEIPFLLSRKYDELSRRVIMDAFAEFERFTCIRFVAY-HGQRDFVSILP----MAGCFSGVGRSGGMQVVSLAPT-----CLRKGRGIVLHELMHVLGFWHEHSRADRDRYIQVNWNEILPGFEINFIKSRSTNML---VPYDYSSVMHYGRFAFSWR-GQPTIIPL--WTSSVHIGQRWNLSTSDITRVCRLYN--CSRSVPDSHGRGFEAQSDGSSLTPASISRLQRLLEALSEESGSSAPSGSRTGGQ-SIAGLGNSQQGWEHPPQSTFSVGALARPPQMLADASKSGPGAGADSLSLEQFQLAQAPTVPLALFPEARDKPAPIQDAFERLAPLPGGCAPGSHIREVPRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6HA08-1", "uniprot_id": "ASTL_HUMAN", "id": "Q6HA08-1", "name": "Astacin-like metalloendopeptidase", "aln": "-----------------------------------------MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQGLILE-----ETP-ESSFLIEGDIIRPSPFRLLSATSN--KWPMGGSGV--VEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTY-QDQRDFISIIP----MYGCFSSVGRSGGMQVVSLAPT-----CLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNML---TPYDYSSVMHYGRLAFSRR-GLPTITPL--WAPSVHIGQRWNLSASDITRVLKLYG--CSPSGPRPRGRGSHAHSTGRSPAPASLS-LQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGS----PALPGGCVPRNHFKGMSED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LW01-1", "uniprot_id": "HE12_DANRE", "id": "Q1LW01-1", "name": "Hatching enzyme 1.2", "aln": "-----------------------------------------MDIRASLS----ILLLLFGLSQASPLR---------EFEAIFVSEPETVDITTQILETNKG-------------SSEVLFEGDVVLPKNRNALICEDKSCFWKKNANNI--VEVPYVVSGEFSINDKSVIANAISIFHAQTCIRFVPR-SIQADYLSIEN----KDGCYSAIGRTGGKQVVSLNRKG----CVYSG--IAQHELNHALGFYHEQSRSDRDQYVRINWNNISPGMAYNFLKQKTNNQN---TPYDYGSLMHYGKTAFAIQPGLETITPI--PDENVQIGQRQGLSKIDILRINKLYG--C-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AVT9-1", "uniprot_id": "A0A8M3AVT9_DANRE", "id": "A0A8M3AVT9-1", "name": "Metalloendopeptidase", "aln": "-----------------------------------------MNAMD-------RILRANQLSRGFPLR-----------------------------------------------------EGDILSPGSRSAITCLGDSCRWPKAVDGF--VYVPYIMSTLYDDMDRITIETGMLDISSSTCVKFVPR-THQANFLNIQP----RYGCWSYLGMTGGSQTVSLQSPG----CMWSG--VASHELMHALGFVHEQSRSDRDRYVSILWENIIENQRHNFRKYETNNLN---TAYDYSSVMHYGRYAFSED-GGPTIIPK--PDPYIPIGQRDGPSILDIHKINILYN--CGGLV-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TRG5-1", "uniprot_id": "A0AB32TRG5_DANRE", "id": "A0AB32TRG5-1", "name": "Metalloendopeptidase", "aln": "-----------------------------------------MFVTKVTFGLLALMLVYSAEGKPAQLS-----------------------VSELLHRANRG---------IIP-EADEPKLLDDIAVNEKNADPCTSYGCLWPKYSDGK--IYVPYVIANHYSSRELEIIQRGLDSFSYSTCIRFFPR-GNERDYISIES----RSGCYSYVGRQGYAQTVSLARSG----CLYHS--TVQHELLHALGFNHEQTRNDRDNHIQVIWENILDDMKYNFNKINTLNQG---TPYDYSSVMQYERYAFSKN-GLPTMIPI--PNNNAALGTSTEMSQNDIIRINRLYQ--CCK---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC98-1", "uniprot_id": "Q9VC98_DROME", "id": "Q9VC98-1", "name": "Metalloendopeptidase", "aln": "----------------------------------------MGKSQNNTGSLLLLIILGISLGDSMPLEDMDSQEMIDLTDLGDTLFGNPDVETTGALVEALGVESP-----LNPEELGTYHEGDILIPLSYRDARFNGTRNGILALSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPR-TTEKDYISIGSG---KSGCWSSIGRLGGRQEVNLQSPN----CLRTYG-TPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRN-GQPTLKALRATSDASQMGQRKGFSAGDVRKINAMYK--CKV---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K600-1", "uniprot_id": "A0A0B4K600_DROME", "id": "A0A0B4K600-1", "name": "Metalloendopeptidase", "aln": "MRHECGVERVGKQRSNGNIVTAKPNPSSIMCAQLSGSVVLLVQLQVAVLLVALLVLSATTLSESAKLPVRQYPAGVDFFEHEFTSVAEVLKPLSDEYDPYGPDIGDDDLGIDDPETMPRLFQGDIAIDPYTYITLRLGVNPMRHPKRLWPN-GTIPFEISPRYANQERQAIIQAVKTFNSLTCVHFVPYDGEVDDYLLIEPPLEGPQGCWSYVGRRGGEQVVSLQRPDENSAHCFSSEGRIMHELMHAIGIYHEQSRADRDNFVKIHWDNIVPRFRKNFKLVSKKKGK-YAFDYDYNSVMHYGEFYFSKRKGEKPTMTP--LQPGVRIGQRKTISKIDCLKINELYG--CLQGRRAKMYRSFCHLLGL-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : * .. :*::* . .:: : ** * :* : :.* *** *.:*: *:: :** .: : ::* ** *** *:::* *: * . . :* * * :: :* * ", "identical_positions": 32, "similar_positions": 38, "identity": "6.34%" }, { "cls_id": "homologset.agr.HGNC:31708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCF7-1", "uniprot_id": "D3ZCF7_RAT", "id": "D3ZCF7-1", "name": "Low-density lipoprotein receptor-related protein 12", "aln": "MARRWSTKESPRRGSAWLLLFLAGVYGNGALAELSENVHISGVSTACGETPEQIRGPTGIITSPGWPSDYPAKINCSWLIRANPGEIITISFQDFDIQGSRRCTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGKSEEPHCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCVQDAHPPTTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEESCPVIVPTRVITAAVIGSLVCGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFPSIRLPMTGRSRNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRETERSHPHRSLFSAESDDTDTENERRDTAGASGGVAAPLPQKVPPTTAVEATVGTGGNSSAQSTRGGHAD-GREVSSVEAPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSTNQNRSPLRQLDTGVSGREDDDDVEMLIPVSDGASDIDANECSRPLLDLASDQVQGFRQPHSSGNPGARTSNRDGPCERCGIVHTAQIPDTCLEAAVKTEACDDEALLLC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUJ9-1", "uniprot_id": "LRP12_MOUSE", "id": "Q8BUJ9-1", "name": "Low-density lipoprotein receptor-related protein 12", "aln": "MARRWSTKESQRRGSAWLLLFLAGVYGNGALAELSENVHISGVSTACGESPEQIRAPSGIITSPGWPSDYPAQVNCSWLIRANPGEIITISFQDFDIQGSRRCTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGKSEQPDCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCASDAHPPTTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMTGRSSNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRETERSRPHRSLFSVESDDTDTENERRDTAGASGGVAAPLPQKVPPTTAVEATVGSGGNSSAQSTRGGHAD-GREVSSVEAPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSTTQNRSPLRQLDTAVSGREDDDDVEMLIPVSDGASDIDANDCSRPLLDLASDQVQGFRQPHSAGNPGVRTSNRDGPCERCGIVHTAQIPDTCLEATVKTETSDDEALLLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y561-1", "uniprot_id": "LRP12_HUMAN", "id": "Q9Y561-1", "name": "Low-density lipoprotein receptor-related protein 12", "aln": "MACRWSTKESPRWRSALLLLFLAGVYGNGALAEHSENVHISGVSTACGETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRACGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSVRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDMAGASGGVAAPLPQKVPPTTAVEATVGACASSSTQSTRGGHADNGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSLSQNQSPLRQLDNGVSGREDDDDVEMLIPISDGSSDFDVNDCSRPLLDLASDQGQGLRQPYNATNPGVRPSNRDGPCERCGIVHTAQIPDTCLEVTLKNETSDDEALLLC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******* * ** **************** ***************:*****.*:**********:***::****:************************.********************************:********.:***************:*.*********************.***********:*..:*:***::*********************************************:**************.******************************************************:********************************************************************************* ***************************************************************************.******************:*************************************************************************************.*:****:*** **********************.**********:***.**.:.******.************* **************************: ..**:********* **:*:***.********************************* .**:*******..***************:***:**:*.*:************ **:***:.: ***.*.************************.::*.*:.********", "identical_positions": 781, "similar_positions": 64, "identity": "90.92%" }, { "cls_id": "homologset.agr.HGNC:31709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D416-1", "uniprot_id": "AR13A_MOUSE", "id": "Q9D416-1", "name": "ADP-ribosylation factor-like protein 13A", "aln": "-------------------------MFRLLTACWSRQKTTEEKQRNVTIIVIGLDNSGKSRLIEAFQRLIPSKMHKEMRPTQTTLLLDDYQVSIYDLTGDVKGREKWSSYYAQAHGLIFVVDSSDIARIQEVKIILTRIMFDKRVSGKPILILANKQDKKNALLPCDIIEYLLLERLVNETRSMCRVEPCSTIKRIPKRQQKPIVVGLRWLLAAIGDQYSELYTRQQIPNMS-ISTSKN-----IRGCGERCLSDSLPNR----VRHSNRQHFDKRQHMEHRQHVEQRHFEKRQHFEARQRLIQRSLDARPLKPILQKD------GFRIRPKKNMSVTFALDVIMEEGECSRKIGAPTISKPCSSQCYDTKTPDPSVDVSLFKAHKPKKRIETWDTEEMFLEDPREETFHSCD---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXT3-1", "uniprot_id": "AR13A_RAT", "id": "Q6AXT3-1", "name": "ADP-ribosylation factor-like protein 13A", "aln": "-------------------------MFRLLTACWSRQKATEGKQRNVTIIVIGLDNSGKSHLVAAFQRLIPSKMHSEMRPTQTTLLLDDYQVSVYDLTGDLKGREKWPNYYAEAHGLVFVVDSSDIARIQEVKIILTRLMFDKRVSGKPILILANKQDKKDALLPCDIIEYLLLERLVNETKSMCRVEPCSTIRNLPKRHQQPIVIGLRWLLAAIGDRYDELCTRHQTPSMSNISSSKN-----IRGCGERCSSDSLSTRGVGVVRNNHRQHFEKRQHLEHRQHVEQRHFEKRQHFESRQHLIQRSLDARPLKPILQKD------GFRIRPKKNMSVTFALDVIMEEGECSRKIGAPNISKPCNSQCYDTKTPAPSADANLFKARRPKKRIETWDTEEMFLEDPRGEAFRSCVTGHSSRSSRNTQSLYFTG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5H913-1", "uniprot_id": "AR13A_HUMAN", "id": "Q5H913-1", "name": "ADP-ribosylation factor-like protein 13A", "aln": "-------------------------MFRLLSSCCSCLRTTEETRRNVTIPIIGLNNSGKTVLVEAFQKLLPSKTDHCMKSELTTLLLDEYELSIYDLNGDLKGREAWPNYYAQAHGLVFVLDSSDIRRMQEVKIILTHLLSDKRVAGKPILILANKQDKKKALMPCDIIDYLLLKKLVKENKCPCRVEPCSAIRNLERRNHQPIVEGLRWLLAVIDT--------CQLPPTSSISISKN-----NTGSGERCSSHSFSTR----------TGMSK---------------------EKRQHLEQCSIEAKPLKSILQKE------GTRLWSKKNMSVTFALDEPMKEGECSRRMRAQNTTKLCYN---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKW5-1", "uniprot_id": "F1QKW5_DANRE", "id": "F1QKW5-1", "name": "", "aln": "MDSDILLYELRRRWCSPWCSPPQVNMFNLMSNCCSWVSKLQQPLRKITVLVVGLDKAGKTSCVRGMLRVPPGDVGPTHGCVRTELRLENYLVNILDIGGGLEVRGSWREHYGEAHGIIFVVDSSDRQRMKEVKETLVDLLKHPRVAGKPLLVLANKQDKMNALLGNELIEILSLERLVNQSRSLCHIEPCSASMDLRRWSDRKTLRGLRWLLRAVCLDYPDLCARVMRDGRRPLGPEEKERKGKIEKSRNKTKDEKIPTSKTDIRQEQHGETVRKNGTLQPIKNILNKENSFKKKLSKKKKVKVKIKKESPSRGVNEEEEIEANEAEQEHNQKDKASSALLPPKRGKLKRKAKVKEENSGLPESPNSELSKPSKGKEERKRKKKTVKVKRKNKINTEEVPAAYTQPVDLSNTFDLYRKAILALKARQEQDMVSG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.*:: * * : *::*: ::**:::**: : .: :: *.. * * *::* :.: *: *.:: * * .:*.:***::**:**** *::*** *. :: . **:***:*:******* .**: ::*: * *::**::.:. *::****: : : .: : ****** .: :. .:: . :: ...:.. . * . :::: . * : : ::: . : :*: : : * : : . :: . ", "identical_positions": 70, "similar_positions": 105, "identity": "16.13%" }, { "cls_id": "homologset.agr.HGNC:31710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61089-1", "uniprot_id": "UBE2N_MOUSE", "id": "P61089-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JXB2-1", "uniprot_id": "UE2NL_HUMAN", "id": "Q5JXB2-1", "name": "Putative ubiquitin-conjugating enzyme E2 N-like", "aln": "MAELPHRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGESKDSPFEGGTFKRELLLAEEYPMAAPKVRFMTKIYHPNVDKLERISLDILKDKWSPALQIRTVLLSIQALLNAPNPDDPLANDVVEQWKTNEAQAIETARAWTRLYAMNSI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35128-1", "uniprot_id": "UBE2N_DROME", "id": "P35128-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MSSLPRRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTG-PNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNIDRLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJS5-1", "uniprot_id": "Q9VJS5_DROME", "id": "Q9VJS5-1", "name": "UBC core domain-containing protein", "aln": "MAALTPRIIKETQRLLEDPVPGISATPDECNARYFHVLVTG-PKDSPFEGGNFKLELFLPEDYPMKAPKVRFLTKIFHPNIDRVGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAELWKVNERRAIQLARECTLKHAMQN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52490-1", "uniprot_id": "UBC13_YEAST", "id": "P52490-1", "name": "Ubiquitin-conjugating enzyme E2 13", "aln": "MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEG-PEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. ******::*: :*****.* *.: * ***:* : * .::**:*.* *: ** *.::*** ******:***:***:*:: **.**:** :*********:******** :***:*******.* * ** * ** * :* :. ", "identical_positions": 88, "similar_positions": 35, "identity": "57.14%" }, { "cls_id": "homologset.agr.HGNC:31713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q504P2-1", "uniprot_id": "CL12A_MOUSE", "id": "Q504P2-1", "name": "C-type lectin domain family 12 member A", "aln": "MSEEIVYANLKIQDPDKKEETQKSDKCGGKVSADASHSQQKTVLILILLCLLLFIGMGVLGGIFYTTLATEMIKSNQLQRAKEELQENVFLQLKHNLNSSKKIKNLSAMLQSTATQLCRELYSKEPEHKCKPCPKGSEWYKDSCYSQLNQYGTWQESVMACSARNASLLKVKNKDVLEFIKYKKLRY-FWLALLPRKDRTQYPLSEKMFLSEE-SERSTDDIDKKYCGYIDRVNVYYTYCTDENNIICEETASKVQLESVLNGLPEDSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QGZ9-2", "uniprot_id": "CL12A_HUMAN", "id": "Q5QGZ9-2", "name": "C-type lectin domain family 12 member A", "aln": "MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVLASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEKMANPVQLGSTY--FREA--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:.**:*::*:..: *: : .* * *... .** : :.*:* ******:**:***..:*:.** ** * *:**. .****.*: *** *:* *:**:***: **: **:********* ********: *:***** :: ***** ***:*:******::**:.***** :. * :**.* *.:* *: :::: *. *.: *::: *****:*: * * :** ::.:***: *. *** *. : * ", "identical_positions": 130, "similar_positions": 76, "identity": "48.33%" }, { "cls_id": "homologset.agr.HGNC:31723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFG1-1", "uniprot_id": "A0ABK0LFG1_RAT", "id": "A0ABK0LFG1-1", "name": "", "aln": "----------------MNLRRSLLGFTFCTCYLASHLTNKYVLSVLKFTYPTLFQGWQTLIGGLLLHMSWKLGWVEINSSLRSDVLTWLPASVLFVGIIYAGSKALSRLAVPVFLILHNAAEVLTCGFQKCVWKEKTSLSKICSALFLLAAAVCLPFQDSQFDPD----------------------GYFWALIHFFCVGSYKILRRSRK-PTVLSDIDQQYLNYIFSMVLLAFASHPTGDLFRAMDFPFLYFYSFYGSCCASGVLGFFLMLSTVKLRNILAPGQCAAWIFFAKVVTAGLSLLLFDMTLTRATVGWLSSGRAHLNDRLVTAWPMLQDKSQFCTNDQFNHSLKCSLSQLQKPQDTDHASYPQYRLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UME2-1", "uniprot_id": "S35D4_MOUSE", "id": "Q3UME2-1", "name": "UDP-N-acetylglucosamine transporter SLC35D4", "aln": "----------------MNVRRSLLGLTFCTCYLASHLTNKYVLSVLKFTYPTLFQGWQTFIGGLLLHMSWKLGWVELHSSPRSDVLIWLPASALFVGIIYAGSKALSRLAVPVFFILHNVAEVLTCGYQKCVWKEKTSLSKICSALFLLAAAGCLPFQDSQFDPD----------------------GYFWALIHIFCVGSYKILRKSRK-PTVLSDIDQQYLNYIFSMVLLAFASHPTGDLFGALDFPFLYFYRFHGSCCASGVLGFFLMLSTVRLRSILAPGQCAAWILCAKVVTAGLSMLLFDMALTKATVGCFLLG------GLGEALLVFSERR--------------SSS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q24JQ0-1", "uniprot_id": "S35D4_HUMAN", "id": "Q24JQ0-1", "name": "UDP-N-acetylglucosamine transporter SLC35D4", "aln": "----------------MCVRRSLVGLTFCTCYLASYLTNKYVLSVLKFTYPTLFQGWQTLIGGLLLHVSWKLGWVEINSSSRSHVLVWLPASVLFVGIIYAGSRALSRLAIPVFLTLHNVAEVIICGYQKCFQKEKTSPAKICSALLLLAAAGCLPFNDSQFNPD----------------------GYFWAIIHLLCVGAYKILQKSQK-PSALSDIDQQYLNYIFSVVLLAFASHPTGDLFSVLDFPFLYFYRFHGSCCASGFLGFFLMFSTVKLKNLLAPGQCAAWIFFAKIITAGLSILLFDAILTSATTGCLLLG------ALGEALLVFSERK--------------SS--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40107-1", "uniprot_id": "GMT1_YEAST", "id": "P40107-1", "name": "GDP-mannose transporter 1", "aln": "MSELKTGHAGHNPWASVANSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGYAKFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQAVAAKAASLAEGAAGAVAS----FNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWS-SVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIG------FLSGIIYAVAKQK--------------KQQ-----AQPLRK--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CE11-1", "uniprot_id": "GMT2_YEAST", "id": "P0CE11-1", "name": "Probable GDP-mannose transporter 2", "aln": "-------------------------------------------------------------------------------------------------MIYTSSKSLQYLAVPIYTIFKNLTIILIAYGEVLFFGGKVTSMELTSFIMMVLSSVVATWGDQQAIAIKASSLEDLDQELVESTIFVLNPGYLWMFTNCISSALFVLIMRKRIRLTNFKDYDTMFYNNVLALPLLLVFSFIMEDWS-TKNLSVNLSADSLAAMVISGLMSVGISYCSGWCVRVTSSTTYSMVGALNKLPIALAGLVFFDAPKNFLSFFSIFLG------FLSGLLYAVAKQK--------------KIQQQKVLAATLEK--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:.*::*. **:*:: ::* : :: . : . ..: :: * :::: :: .: *.* . **:* : : : . : :: :.: : :.* * : * :::: :* . *. * ::. : **. .. : .: : :. : *: * .:::** . : : * * . .: . ", "identical_positions": 28, "similar_positions": 80, "identity": "7.47%" }, { "cls_id": "homologset.agr.HGNC:31729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJ65-1", "uniprot_id": "D3ZJ65_RAT", "id": "D3ZJ65-1", "name": "", "aln": "MAR-AVGVR---GRVARYGRWRRGALLAFAAWTAGWVLAAALLLRAHPSVLSERCTDEKSRRILAALCRDYRGGWLTGALCEDLCVAG-ELLYQRCLYYERGKKVLQAQWRGQTVVLKSKREAFSSFPPLNLLEEE---AGPGAP-IPEAELLLMVAGEVKNTLGLELPNNSIAP-LWPARQGPG----WRQELASAWSLLQQEEYVYFSLLPDLSRHILPVLGSCGHFYAVEYLAAGSPHHKALFPLDDA---------GQAQAISHIALSFLDMVSHFDSDFSHRLHLCDVKPENFAIKRDFTVVAIDVDMAFFEPKMREILEQ--NCTGDEDCNFFDCFSKCDLRVNKCGARRVNSNLQVICDKIFQ---HWFSSSHRSPAISPQLQLQLQQAVQECAHHGDPSGNSWTASSSVFWKLRWLLQATLKELQEVEK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQT2-1", "uniprot_id": "DIK1C_MOUSE", "id": "Q8BQT2-1", "name": "Divergent protein kinase domain 1C", "aln": "MAR-AAGER---GRAARCGRWRRGALLAFAAWTAGWVLAAALLLRAHPSVLSERCTDEKSRRILAALCQDYRRGWLTGALCEDLCVGG-ELLYQRCLYYERGKKVLQAQWRGRTVVLKSKREAFSSFPPLTLLEEE---AGAGAPGIPEAELLLMVAGEVKNTLGLELPNNSIAP-LWPARQGPG----WRQQLASAWSLLQQEEYVYFSLLPDLSRHILPVLGSCGHFYAVEYLAAGSPHHKALFPLDDA---------GQAQAISHIALSFLDMVSHFDSDFSHRLHLCDVKPENFAIKRDFTVVAIDVDMAFFEPKMREILEQ--NCTGDEDCNFFDCFSKCDLRVHKCGAQRVNSNLQVICDKIFR---HWFSSTHRSPAVSLQLRLQLQQAVQECAQHGGSSGNSWTASSSVFWKLRWLLQATLKELQEAEK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0P6D2-1", "uniprot_id": "DIK1C_HUMAN", "id": "Q0P6D2-1", "name": "Divergent protein kinase domain 1C", "aln": "MAR-AAGARGPAGWCRRRGRCGRGTLLAFAAWTAGWVLAAALLLRAHPGVLSERCTDEKSRRILAALCQDYQGGTLAGDLCEDLCVAG-ELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEEAFSSFPPLSLLEEE---AGEGGQDMPEAELLLMVAGEVKSALGLELSNSSLGP-WWPGRRGPR----WRGQLASLWALLQQEEYVYFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDRAPGAPGG---GQAKAISDIALSFLDMVNHFDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDMAFFEPKMREILEQ--NCTGDEDCNFFDCFSRCDLRVNKCGAQRVNNNLQVICDKIFR---HWFSAPLKSSAVSFQLQLQLQEAVQECADPGVPSGNTRRAASSVFWKLRQLLQATLRELQEAEK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7V0B0-1", "uniprot_id": "A0A8N7V0B0_DANRE", "id": "A0A8N7V0B0-1", "name": "", "aln": "MWRPLRGALGSARRCLGVKVCRRSALLVVLLWLVSWIFLNGLVF-VHRNMFSDFCTDDKSKEILQRVCDEYHQGVLTGDLCDDLCVSG-QVEYKRCLYYENGKKVMAASWRGLPVVLKSKLENFSSYEALSLLDYPDGGAGGGEDELSPLDVVFYATLEIKNSLGLETGNNLTLPRLWGQRLKESERMYSRAELASLWALLQQEEYTFLRVLQDLTNHVAKILGSCGHFYAVEYLAAGHAWDQHIFSLDELTLSPSPSTFSVKEMVPRVALSFLEMVEHFENDFSHRLHLCDIKPENFAIRKDLTVVAIDVDMAFFEPKMREILEQ--NCTNDSDCNFFDCISKCDKTKNRCGSKRRNSNLQVICEKIFR---PWFSPTLLGAKAGLPLQVELQRAVQECAEMED-SEHRQDIRQQLYALLRELVQEDTGHPRGGQEHKRRRVHTALNF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVC9-1", "uniprot_id": "Q7KVC9_DROME", "id": "Q7KVC9-1", "name": "", "aln": "-------MLTALRRKIRFG-MQRTVLIAVLLAVG--IFSYAFLN-------LKFCFKLMSHRSLNLMCQKFEKHEYSGSLCEELCGSQSSFDNFQCPLNDMKTILFTAEKNGDLYAVKLAR---HNDDELSWTNNK-----GESIYPKLEEFHEIVKLHIILAYNVTLDDNMIRALVNQEIADDN-----SQQMVSFWRLFKDNNYMMGKLFDEES-IFPAVLGSCGPYYATEGLEIVQSNPSIMQYLASN-----------RVQRLKHALNIMEYIFRLDEMKPEPLKMCKMQVNRFGTASERRLKYQSAEHVYVESQLDKRLSRGVKCHAHQDCHFHSCRGLCDEEKQSCTHIQQNNNFQIFCEHILLGGGTFQPGLLSGVRLSKALQKLVKMCVQPPKEHQVPGRQWAPNTQLALRLYNELKQLHQAATASAGSVIPDEGQARRGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*:.. :: .:: . * . *:. * :* .:. :* **::** . .. :* : . :: *. .* .:* . *. : :. . .: : .: :. . ::.* * *:::::* :: : : . :***** :**.* * . : * **.::: : :::. .. *::*.:: :.*. : : ..: .:.*.:: : *.: :* ..**:*..* . ** : * : *.*:*::*::*: : . . . *: :: .** . . : . . * * . ", "identical_positions": 55, "similar_positions": 127, "identity": "12.25%" }, { "cls_id": "homologset.agr.HGNC:3173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35474-1", "uniprot_id": "EDIL3_MOUSE", "id": "O35474-1", "name": "EGF-like repeat and discoidin I-like domain-containing protein 3", "aln": "MKHLVAAWLLVGLSLGVPQ-FGKGDICNPNPCENGGICLSGLADDSFSCECPEGFAGPNCSSVVEVASDEEKPTSAGPCIPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEAEPCRNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEEMVFRGNVDNNTPYANSFTPPIKAQYVRLYPQICRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSVFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWMVHQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARFIRILPWSWYGRITLRSELLGCAEEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKH0-1", "uniprot_id": "A0A8I6GKH0_RAT", "id": "A0A8I6GKH0-1", "name": "", "aln": "MKHLVAAWLLVGL-LGVPQ-FVKGDICNPNPCENGGICLSGLADDSFSCECPDGFTDPNCSSVVEVG----------PCIPNPCHNGGTCEISEAYRGDTFIDYVCKCPQGFNGIHCQHNINECEAEPCRNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEEMVFRGNVDNNTPYANSFTPPIKAQYVRLYPQICRRHCTLRMELFGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDAKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43854-1", "uniprot_id": "EDIL3_HUMAN", "id": "O43854-1", "name": "EGF-like repeat and discoidin I-like domain-containing protein 3", "aln": "MKRSVAVWLLVGLSLGVPQ-FGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IMA9-1", "uniprot_id": "A0A0R4IMA9_DANRE", "id": "A0A0R4IMA9-1", "name": "", "aln": "-MGPLLVSIALCVHLAVPH-LVKA--------ADG--------------------EDPTSAG---------------PCHPNPCHNGGICEISETFRGDTFIGYVCKCPSGFNGIHCQHNVNECERSPCRNGGICTDLVANYSCECPGEYMGRNCQYKCSGPLGMEGGIISNQQITASSTHRALFGLQKWYPYFARLNKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYKVKGTDEDIIFRGNIDNNTPFANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELSGCSEPMGMKSGHIQDYQITASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQKKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLRAELLGCTEEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q6J1-1", "uniprot_id": "F1Q6J1_DANRE", "id": "F1Q6J1-1", "name": "", "aln": "-MLPVFLLLFVRTGASLPHPTSAGEVCEPVPCENS-------------ADCPTTPADENGSSASDWK----EQSIIGPCRPNPCHNGGLCELNQTDRGDALLGYLCRCPAGFNGVHCQHNVNECEKNPCRNGGSCTDLQANYTCLCPGEYMGQNCQYKCSGPLGMEGGIISNQQITASSTHRALFGLQKWFPYFARLNKKGLVNAWSAAEGDRYPWIQINLLRRMRVTALITQGAKRIGSPEYVKSFKVAYSEDGKAWSLFKVKGTDEDMIFTGNTDNSSPSVNSFSPPIEAQYIRVYPQICRKHCTLRMELLGCELTGCSEPMGMKTGHIQDYQLSSSSVFQTLSMDMFSWDPSKARLDKQGKVNAWTSAHNDQSQWLQIDLLIPTKVTGIITQGAKDFGHVQFVGSFKLAFSNDGEKWIIYQDEKQHKDKIFQGNFDNETHRKNVIDPPIYARFVRILPWSWYGRITVRMELLGCPEEQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .:*: . :. . . :. ** ******** **:.:: ***:::.*:*:** ****:*****:**** .**:*** **** ***:* ****:**:***********:*************************:**:********:***:***.**:******* *:****.:*************:**:*:***:***:* :*****:*:::* ** **.:* .***:***:***:*:***:**:********:****:*****:***:*******:::**:*:**.****:*:* ***************.*.*******:*:* ***:*******************:*:*:**:**:* ::** **:***:*******:**************.:************:* *****.**:", "identical_positions": 308, "similar_positions": 91, "identity": "64.03%" }, { "cls_id": "homologset.agr.HGNC:31736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48610-1", "uniprot_id": "KARG_DROME", "id": "P48610-1", "name": "Arginine kinase 1", "aln": "-----------------------------------M------------------------VDAAVLAKLEEGYAKLAAS-------------------------------DSKSLLKKYLTKEVFDNLKNKVTPTFK-STLLDVIQSGLENHDS----GVGIYAPDAEAYTVFADLFDPIIEDYHGGFKKTD--KHPASNFGDVSTFGNVDPTNEYVISTRVRCGRSMQGYPFNPCLTEAQYKEMESKVSSTLSGLEGELKGKFYPLTGMEKAVQQQLIDDHFLFKE-GDRFLQAANACRFWPSGRGIYHNDAKTFLVWCNEEDHLRIISMQQGGDLGQIYKRLVTAVNEIEKRVP-----FSHDDRLGFLTFCPTNLGTTIRASVHIKVPKLASNKAKLEEVAAKYNLQVRGT-RGEHTEAEGGVYDISNKRRMGLTEFEAVKEMYDGITELIKLEKSL-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VST4-1", "uniprot_id": "Q9VST4_DROME", "id": "Q9VST4-1", "name": "arginine kinase", "aln": "------MLLHLKLRLELQLLGRCAQLVINRHASKGN------------------------VDKEVMEQMEKGYKKLAES-------------------------------KSKSLLKKHLTKEIFEKLKTKTTPSFN-STLLHCISSGMCNHDS----GVGLYAPDPEAYKVFADLFDPVIEEYHKCFKKTD--KQPATAFGKGADFENLDPDGHFIVSTRVRCGRAVKGYPFNPCLTEADYMELESKICGAVTSLTGEYKGKYMPLTGMDKCIQEQLIEDHYLFKE-GDRFLASAGASRYWPTGRGIFLNSAKNFLVWCNEEDHIRIISMEKGGDLGKVYDRMVGGVEALGKQLQ-----FNRDERLGFLTFCPTNLGTSIRASVHIKLPNLMCDPDEMKKLADKYRLQIRGT-SGEHSEAKGGVHDISNQRRMGLTEYEIIKEMHDGIKGLIEAECKAKSA--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25809-1", "uniprot_id": "KCRU_RAT", "id": "P25809-1", "name": "Creatine kinase U-type, mitochondrial", "aln": "MAGPFSRLLSARPGLKLLALAGAGSLAAGILLRPES------------------------VRAATGERRRL-YPPSAEYPD---------------------------LRKHNNCMASHLTPAVYARLCDKTTPTG--WTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRT--MKHTTDL-DASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKKVEKLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVKLP-LLSKDSRFPKILENLRLQKRGT-GGVDTPATADVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLEKGQDIRIPPPLVHGKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30275-1", "uniprot_id": "KCRU_MOUSE", "id": "P30275-1", "name": "Creatine kinase U-type, mitochondrial", "aln": "MAGPFSRLLSARPGLRLLALAGAGSLTAGILLRPES------------------------VGAAAAERRRL-YPPSAEYPD---------------------------LRKHNNCMASHLTPAVYARLCDKTTPTG--WTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRT--MKHTTDL-DASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVEKLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLP-LLSKDNRFPKILENLRLQKRGT-GGVDTAATGSVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPPPLVHSKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12532-1", "uniprot_id": "KCRU_HUMAN", "id": "P12532-1", "name": "Creatine kinase U-type, mitochondrial", "aln": "MAGPFSRLLSARPGLRLLALAGAGSLAAGFLLRPEP------------------------VRAAS-ERRRL-YPPSAEYPD---------------------------LRKHNNCMASHLTPAVYARLCDKTTPTG--WTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRT--MKHTTDL-DASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLP-LLSKDSRFPKILENLRLQKRGT-GGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF23-1", "uniprot_id": "Q9VF23_DROME", "id": "Q9VF23-1", "name": "arginine kinase", "aln": "MTSIESKRVQYRKYLERAGVIDALSKALIKLYEEQNKPEDAIRFVRKFMCESCPDDAQYDVMKNDLEEAKTHISKLEQELERLRGQIKKSPEEYQELTTEGYKSLMDDEENVSSLLRKYLTPELLEEYMLVTTPAPVDAYLYDCAVSGFEHHDAP----VGIFAADADSYDVFNKLFDPIIKDYHGQMDNENDVLQKDPDFGNVDEIENLDPERKYILSARIRLARNIEGLPFFPKLTEKQFIEVEEKVRSATETMDGELIGSYLTMADIDAETQAEMVKRHILFQR-GDEKLTTAGCYRFWPTGRGVYHNPAETFLIWVNRQDHVHIMSMAQCGDLGDVYNRLVNGLTELEKTLA-----FARHPRYGNLTACPTNLGTTLRASVHIRLPLLSKDPDRLLALAEEQQLQVRGTDGGELSTVEDGVMDISNKRKLGFTEFELVKTLQDGVVTLINAEEELEISGQEG----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . .. : .:** : . .**: * . :*. : . **: * * ::* ** .****:*:: * . : . : . : . .:::*:*:* .* :.* .: * *. : *:* : .: : *: * : :: : * :::. * **.. . * :*. * ** .**:: * :.**:* *.:** :::** : *:: ::.*: .: : : : * . * * : **:**** :**.**:::* * . .: : : .** *** * : . .* **** ::* :* * :: : **: **. * ", "identical_positions": 87, "similar_positions": 111, "identity": "18.24%" }, { "cls_id": "homologset.agr.HGNC:31746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08EJ0-1", "uniprot_id": "PL8L1_MOUSE", "id": "Q08EJ0-1", "name": "PLAC8-like protein 1", "aln": "MSWMGHHFSRWCKDISVLSSHLPLFSPMPSEDEHLISNLRSHVPARVVVKQPIRGAIGRTTVAAIVQTGGDWSTGLFSVCRDRKICFWGLLCPMCLECDIARHYGECLCWPLLPGSTFALRIGTRERHRIQGTLCEDCVVVHCCWPFSICQVARELKMR-TSQLYEICEVPELKNTLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTM1-1", "uniprot_id": "D3ZTM1_RAT", "id": "D3ZTM1-1", "name": "", "aln": "MSWLGHHFSRWCEDISLLSTHIPLFSPMPSEDEHLISDLRSHVPACVVVKQPIRGASGRTTVTAIVQTGGDWSTGLFSVCRDRKICFWGLFCPMCLECDIARHYGECLCWPLLPGSSFALRIGTRERHKIQGTLCEDWVVVHCCWPFSICQVARELKMR-TSQLYEICEVPELKDTLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1L4L8-1", "uniprot_id": "PL8L1_HUMAN", "id": "A1L4L8-1", "name": "PLAC8-like protein 1", "aln": "MNWFGSNFFRCPEDLSLLNIYSPLLSHMSSEDEHFISNLRGHVPASAVVKQPVRGASGRTTITAIVQTGGGWSTGLFSVCRDRRICFCGLFCPMCLECDIARHYGECLCWPLLPGSTFALRIGTRERHKIQGTLCEDWLAVHCCWAFSICQVARELKMR-TSQVYEICAVPMTKDTLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDI5-1", "uniprot_id": "E7FDI5_DANRE", "id": "E7FDI5-1", "name": "", "aln": "MDSPG------PNDVEVN--------PVGSEK-----------MECPVLTQPGLGET-TTTVTTVTQTGGDWSTGLFDVCGDASTLLMGTFVPCCLDLSLAHQYGECMCLPLLPGSTFAMRVGIRERFKIRGNVCEDWMTVYCCYPLALCQMIREMKRRLKTQIYTVSTALESS----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * :*:.: : **. *:.** * **::::.****.******.** * : * : * **: .:*::****:* ******:**:*:* ***.:*:*.:*** :.*:**:.:::**: **:* * .:*:* :. . . ", "identical_positions": 63, "similar_positions": 49, "identity": "35.39%" }, { "cls_id": "homologset.agr.HGNC:31748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02781-1", "uniprot_id": "PSC2_RAT", "id": "P02781-1", "name": "Prostatic steroid-binding protein C2", "aln": "MRLSLCLLTI-LVVCCYEANGQTLAGQVCQALQDVTITFLLNPEEELKRELEEFDAPPEAVEANLKVKRCINKIMYGDRLSMGTSLVFIMLKCDVKVWLQINFPRGRWFSEIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6XE38-1", "uniprot_id": "SG1D4_HUMAN", "id": "Q6XE38-1", "name": "Secretoglobin family 1D member 4", "aln": "MRLSVCLLMVSLALCCYQAH-----ALVCPAVASEITVFLFLSDAAVNLQVAKLNPPPEALAAKLEVKHCTDQISFKKRLSLKKS----------------------WWK---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*** : *.:***:*: . ** *: . .**: .: :: :: :::.****: *:*:**:* ::* : .***: .* *:. ", "identical_positions": 32, "similar_positions": 33, "identity": "28.32%" }, { "cls_id": "homologset.agr.HGNC:31749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1Q6Z5-1", "uniprot_id": "F1Q6Z5_DANRE", "id": "F1Q6Z5-1", "name": "", "aln": "MDMSTSECFGCGRSGHWIKNCP---------NAG-RGRG-RGRGRG-------KDLFCYRCGEQGHIARDCEQTEDACYNCHRSGHISRDCKEPKKER---EQCCYNCGKAGHVARDCDHAN------EQKCYSCGGFGHIQKLCDK--VKCYRCGEIGHVAVQCSKATEVNCYNCGKTGHLARDCSIEASA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M0R729-1", "uniprot_id": "M0R729_RAT", "id": "M0R729-1", "name": "", "aln": "--MSGKSCFKCGRSGHWARECP---------KGGTRGRTTRGRTRGPQCSSASQSDVCYRCGETGHYAKDCDLLQDTCYNCGRRGHIAKDCTQAKRER---EQCCYICSRPGHLARDCDRQE------EQKCYTCGEFGHIQKDCTQ--IKCYRCGENGHMAVNCSKASEVSCYRCGESGHLARECPIEATA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WW36-1", "uniprot_id": "ZCH13_HUMAN", "id": "Q8WW36-1", "name": "Zinc finger CCHC domain-containing protein 13", "aln": "--MSSKDFFACGHSGHWARGCP---------RGGAGGRRGGGHGRGSQCGSTTLSYTCYCCGESGRNAKNCVLLGNICYNCGRSGHIAKDCKDPKRER---RQHCYTCGRLGHLARDCDRQK------EQKCYSCGKLGHIQKDCAQ--VKCYRCGEIGHVAINCSKARPGQLLPLRQIPTSSQGMSQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53849-1", "uniprot_id": "GIS2_YEAST", "id": "P53849-1", "name": "Zinc finger protein GIS2", "aln": "--MSQKACYVCGKIGHLAEDCDSE-------RLCYNCNKPGHVQTDCTMPRTVEFKQCYNCGETGHVRSECTVQR--CFNCNQTGHISRECPEPKKTSRFSKVSCYKCGGPNHMAKDCMKEDGI---SGLKCYTCGQAGHMSRDCQND-RLCYNCNETGHISKDCPKA------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8T8R1-1", "uniprot_id": "CNBP_DROME", "id": "Q8T8R1-1", "name": "CCHC-type zinc finger nucleic acid binding protein", "aln": "-MSMSATCYKCNRPGHFARDCSLGGGGGPGGVGGGGGGGGGGMRGNDGGGMRRNREKCYKCNQFGHFARACPEEAERCYRCNGIGHISKDCTQADNPT------CYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPETSKTCYGCGKSGHLRRECDEKGGRN--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: ** . * . ** *.: *: * *:.* ***:::* :... ** *. .* .::* . .**.*. **:.: * : ** *.: **: :* : ", "identical_positions": 32, "similar_positions": 35, "identity": "16.67%" }, { "cls_id": "homologset.agr.HGNC:31750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N8I0-1", "uniprot_id": "SAM12_HUMAN", "id": "Q8N8I0-1", "name": "Sterile alpha motif domain-containing protein 12", "aln": "MAVEALHCGLNPRGIDHPAHAEGIKLQIEGEGVESQSIKNKNFQKVPDQKGTPKRLQAEAETAKSATVKLSKPVALWTQQDVCKWLKKHCPNQYQIYSESFKQHDITGRALLRLTDKKLERMGIAQENLRQHILQQVLQLKVREEVRNLQLLTQGTLLLPDGWMDGEIRRKTTLL--------------------------------LGQTGVRENLLLFLHR--ISIIENSIQI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VE29-1", "uniprot_id": "SAM12_MOUSE", "id": "Q0VE29-1", "name": "Sterile alpha motif domain-containing protein 12", "aln": "MAVEALHCGLNPRGIDHSAHADGIKLQIEGEGVESQSIKNRTFQKVPDQKGTPKRLQGEAETAKSATVKLSKPVALWTQQDVCKWLKKHCPNQYQLYSESFKQHDITGRALLRLTDKKLERMGIAQENQRQHILQQVLQLKVREEVRNLQLLTQASVECSP-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LW70-1", "uniprot_id": "A0ABK0LW70_RAT", "id": "A0ABK0LW70-1", "name": "", "aln": "MAVEALHCGLNPQSIDHPAHADGIKLQIEGEGVESQSIKNRNFQKVSDQKGTPKRLQGEAETAKSATVKLSKPVALWTQQDVCKWLKKHCPNQYHIYSESFKQHDITDIHQGSEKAKSHTRRKYFLKSTYNSIHETAQMGRPFEERKWTRASPAETHRQEAGAHGGRPGEPATAHPAAGAPTEGSGRSQKPAVTHTRYPAASWWVGAPGEHGKTEHVIIATEESQKKFVVVSLQNFLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8ML92-1", "uniprot_id": "AVE_DROME", "id": "Q8ML92-1", "name": "Protein aveugle", "aln": "---------------------------MGEETINSTQNKTR------------------------TKTTRPKAVYLWTVSDVLKWYRRHCG-EYTQYEQLFAQHDITGRALLRITDSSLQRMGVTDNRDREAIWREIVKQRLKTDIMEIRDMERLNIY--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::* . *.: :... .*.* *** .** ** ::** :* *.: * *****. . .. * : : * . : : : . ", "identical_positions": 24, "similar_positions": 29, "identity": "10.08%" }, { "cls_id": "homologset.agr.HGNC:3176", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22387-1", "uniprot_id": "EDN1_MOUSE", "id": "P22387-1", "name": "Endothelin-1", "aln": "MDYFPVIFSLLFVTFQGAPETAVLGAELSTGAENGVQSPPPSTPWRPRRSKRCSCSSLMDKECVYFCHLDIIWVNTPERVVPYGLGGSSRSKRSLKDLLPNKATDQAVRCQCAHQKDKKCWNFCQAGKELRAQSTMQKSLKDSKKGKPCSKLGKKCIYQQLVEGRKLRR----------LEAISNSIKASFRVAKLKAELYRDQKLTHNRAH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22388-1", "uniprot_id": "EDN1_RAT", "id": "P22388-1", "name": "Endothelin-1", "aln": "MDYFPVIFSLLFVAFQGAPETAVLGAELSPRAEKEVQSPPPSTSWRPRRSKRCSCSSLMDKECVYFCHLDIIWVNTPERVVPYGLGSPSRSKRSLKDLLPTKTTDQGNRCQCAHQKDKKCWNFCQADKELRAQSTMQKGVKDFKKGKPCPKLGKKCIYQQLVEGRKLRR----------LEAISNSIKTSFRVAKLKAELYRDQKLIHNRAH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05305-1", "uniprot_id": "EDN1_HUMAN", "id": "P05305-1", "name": "Endothelin-1", "aln": "MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSP-RSKRALENLLPTKATDRENRCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: :*******: **************. .*: :.*.**..** *******************************:*******.. ****:*::***.*:**: ***** ************.*****:. *:*. :: **** *.************.***:** *:: **:*:**: .***.: *:: : ***** ", "identical_positions": 140, "similar_positions": 41, "identity": "65.73%" }, { "cls_id": "homologset.agr.HGNC:3177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22389-1", "uniprot_id": "EDN2_MOUSE", "id": "P22389-1", "name": "Endothelin-2", "aln": "MVS---AWCSIALALLLALHEGKGQAAATLEQPASAPKGRGPHLRFRRCSCNSWLDKECVYFCHLDIIWVNTAGQTAPYGLGNPPRRRRRSLPKRCECSTAGDSACATFCHRRHWPEAVVAPSSQAPAAVLKTGKMWTAEGDLLRKLRDISATKLRFARLQPEVTRKAIPAYSRWRKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23943-1", "uniprot_id": "EDN2_RAT", "id": "P23943-1", "name": "Endothelin-2", "aln": "MVSP--AWCSIALALLLALHEGKGQAAATMEQPASAPKGRGPHLRFRRCSCNSWLDKECVYFCHLDIIWVNTAGQTAPYGLGNPPQRRRRSLPKRCECSSAGDSACATFCHRRPWPEAEVTSSSQGPAAVLETSKTWTAAGDLLQKLRDISAAKLQFVRLRPELTREAIPAHSRRRKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20800-1", "uniprot_id": "EDN2_HUMAN", "id": "P20800-1", "name": "Endothelin-2", "aln": "MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1MT02-1", "uniprot_id": "Q1MT02_DANRE", "id": "Q1MT02-1", "name": "", "aln": "-MAFTLQTALLVLATLCVLQQGFGYPLSKQPEASSNPPAH-KRVRTKRCSCSSWLDNECIYFCHLDIIWVNTPNKITPLGLGSPLSRRRRSTG-RCECANPADRTCSSFCHTSSEDPDMEFVTQLD----NQSDHKDKTSDHLLLSLRRVVKHNLMTASRFASPKKKSRIS-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :.** * .*::* * . :. :.:* . .: ::* :****.****:**:************. : :* ***.* ***** **:*:.. * :*::** : ::.: : ..** ** : : . . ::. : ", "identical_positions": 51, "similar_positions": 50, "identity": "28.65%" }, { "cls_id": "homologset.agr.HGNC:3178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13207-1", "uniprot_id": "EDN3_RAT", "id": "P13207-1", "name": "Endothelin-3", "aln": "----MELGLWLLLGLTVTSAA--------------------------------------------AALPAQ---PGNAGQERGPGRSG-DQEEKRVP----AHHRPRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNHRGSLRGKRSSGPVPESSQSSPQTRLRCACSGVDDKACAYFCAH---VTSYSRRAEKAAAEEKQETGGPRQ-----------RLKSRTDKVHQP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48299-1", "uniprot_id": "EDN3_MOUSE", "id": "P48299-1", "name": "Endothelin-3", "aln": "----MEPGLWLLLGLTVTSAAGLVPCPQSGDSGRASVSQGPPEAGSERGCEETVAGPGERIVSPTVALPAQ---PESAGQERAPGRSG-KQEDKGLP----AHHRPRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRESLRGKRSLGPVPESSQPSPWTRLRCTCMGADDKACAHFCARTRDVTSYSGRAERPAAEEMRETGGPRQ-----------RLMSRTDKAHRP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14138-1", "uniprot_id": "EDN3_HUMAN", "id": "P14138-1", "name": "Endothelin-3", "aln": "----MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEE----TVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAP----EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IIJ3-1", "uniprot_id": "A0AC58IIJ3_DANRE", "id": "A0AC58IIJ3-1", "name": "Endothelin-3", "aln": "MAKLIPDALLLIVSLINIFTVD-------------------------------------------TSFSSEGDLHSSPVFSGGSSSVGHQQKEAKLVSASHAHTRSKRCTCYSFKDRECVYYCHLGIIWINTPQRTVPYGMSSYRSPQRLRRSSGTISVVLR-------RCLCTDHNDVHCYNFCDASSENVSEGRLRGRSP-----------------------WFWIFTDLE----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* *:..* :. .: ..: .. ... * .* * *.:****:::**:********.*******::*****:*.:* . * :** *.:. : ** * . * * ** * . :. : :. ", "identical_positions": 47, "similar_positions": 43, "identity": "18.8%" }, { "cls_id": "homologset.agr.HGNC:31789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TYU2-1", "uniprot_id": "AT135_MOUSE", "id": "Q3TYU2-1", "name": "Probable cation-transporting ATPase 13A5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKSKKD----------------------------------GHQAVLNEGEENELEVFGYHTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADTILLRT--TDEFRRYMRKKVFCLHLSTLKFPISKNPE-----------EPLVADHHSVINQAVMKPELKLRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTNEEQEVRRLVCGPNSIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEEHNKVQVTITVRDKGLQELESRLLVPGDILILPG--KISLPCDAILIDGSCVVNEGMLTGESIPVTKTPLPQTENTMPWKSHSLEDYR----KHVLFCGTEVIQVKPS-AQGLVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACVGVVGFFYALGVYMYHEVPPRETATMALILLSATVPPVLPAALTIGNVYAQKRLKKEKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTAGNCFQAVHS------------------FASGEAVPWGPLCAAMTSCHSLILLDGTIQGDPLDLKMFEGTGWNMEDS--QVASCKFGMADSSTVIKPGPKAS---------------QSPVDSITILR---------------QFPFSSGLQRMSVIAQLAGDLHLHVYMKGAPEMVARFCRSETVPKNFSQELRNYTVQGFRVIALAHKTLKMER-LSDMDHLAREKVESELAFLGLLIMENRLKKETRPVLKELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVVIVEANEPGDLVPASVTWQLVGTQEPGSGK------------------------------------------------------KDTYIDIGNSSVPAGKG-------------------------------YHFAMSGKSYQVLFHHFY----SMLPQILVNGTIFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKTANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYP-KLAPYRPAGQLLSPQLLLSVFMNSCFTCIVQVCTFLTVKQQPWYCEVYKYSECFLVNQSNLSANVSLDRNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYANYLFSLLLASAAGLTIFILFCDFQDLYRKMEFIPTPTS-WRVSILIAAFVQFCVAFFVEDAVLQNRELWLFIKKEFG--FYSKSQYRILQRKLAEDSTWPPVNRTDYAVNGKNGFYVNRAYESPEEVPKGKLKLEEQASEQHFWTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MA70-1", "uniprot_id": "F1MA70_RAT", "id": "F1MA70-1", "name": "Cation-transporting ATPase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKSKTD----------------------------------GHQAVLNEGEENELEVFGYQTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADIVLLRT--TDEFRRYMRKKVFCLHLSTLKIPISKNPG-----------EPLVADHHSVINQAVMKPELKLRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEDHNKVQVTITVRDKGLQELESRLLVPGDILILPG--KISLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQTENTMPWKSHSLEDYR----KHVLFCGTEVIQVKPS-GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACIGVVGFFYALGVYLYHEVPPRETVTMALILLTATVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTAGNCFQAVHS------------------FASGEAVPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEGTGWNMEDG--QVASCKYSTADSGTVIKPGPNAS---------------QSPVDSITILR---------------QFPFSSGLQRMSVIAQLAGDLRLHVYMKGAPEMVARFCSSETVPKNFPQELRNYTVQGFRVIALAHKTLKMEK-VSDVERLAREKVESELAFLGLLIMENRLKNETRPVLQELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVIIVEANEPGDLVPASVTWQLVGTQEPGSEKKVSQGSQQCF---------------------------------RSPCRNHAFRFQDTYIDIGNSSVPCGKG-------------------------------YHFAMSGKSYQVLFHHFY----SMLPQILVNGTVFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKVANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYP-KLAPYRPAGQLLSPQLLLSVFMNSCFTCIVLVCTFLSVKQQPWYCEVYKYSECFLVNQSNFSTNMGLERNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYTNYLFSLLLTSAVGLTVFILFSDFQDIYRRMEFIPTTTS-WRISILVAAFVQFCVAFFVEDAILQNRELWLFIKKEFG--FYSKSQYRILQRKLAEDSTWPPTNRTDYAVNGKNGLYINRAYESPEQVPKGKLKLGGQASEQHFWTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VNC0-1", "uniprot_id": "AT135_HUMAN", "id": "Q4VNC0-1", "name": "Probable cation-transporting ATPase 13A5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEENSKK----------------------------------DHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIPCPLQEADTVLLRT--TDEFQRYMRKKVFCLYLSTLKFPVSKKWE-----------ESLVADRHSVINQALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPG--KFSLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYR----KHVLFCGTEVIQVKPS-GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHS------------------FASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDC--IVDSCKFGTSVS-NIIKPGPKAS---------------KSPVEAIITLC---------------QFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLKMGN-LSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGK------------------------------------------------------KEIYMHTGNSSTPRGEGGS----------------------------CYHFAMSGKSYQVIFQHFN----SLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYP-KLAPYRPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVIYRGMELIPTITS-WRVLILVVALTQFCVAFFVEDSILQNHELWLLIKREFG--FYSKSQYRTWQKKLAEDSTWPPINRTDYSGDGKNGFYINGGYESHEQIPKRKLKLGGQPTEQHFWARL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZ26-1", "uniprot_id": "A8DZ26_DROME", "id": "A8DZ26-1", "name": "Cation-transporting ATPase", "aln": "----------------------------------------------------------------------------------------------------MFASQSKACDSPSETVHL--------------QSLPNHIEDLKFRNSDVETDDDLHFPGIAAKNKILKLSWWHSPVDMHYVATESVQPKKSDKVPSNKIKKVENNNTLVNGCSKTSARSVPLLKYNRPDQDGDSEENITSVLEPNVDEIYSKDSERLVDDSK----------------------------------PCIGLLNPDQEDQMKVCGYRRSLMRTGFCWACIFLTGGLLRLVLHWWRHLYLYATCSQCSLEEAEQVLVTEDYQGKHKMYHVKQIQVLTSSNLKTLLEKEQQSIERTHIECDHVENVLQLSVHFTSAQFKKCSSIRIFRCKQLVYAWNNNTNRFQRINGLDLNIPCSYYHQQR--GLPVHEQISRRIVFGDNEITVPLRDFKTLLFLEVLNPFYVFQLFSVILWFTYDYYYYACVILLMSVFGITVSVLQTKKNQDVLQKTVYNTGNAWVVDHKG--LSKELPTRAIVPGDIIEIPSS-GCTLHCDAILISGNCILDESMLTGESVPVTKTPLPSKRD----MIFDKTEHA----RHTLFCGTKVIQTRYI-GSKKVLAFVINTGNITAKGELIRSILYPPPVDYKFEQDSYKFIQFLAIIACVGFIYTLVTKILRGTDPVKIAVESLDLITIVVPPALPAAMTVGRFYAQKRLKTSEIFCISPRSINVAGSINCCCFDKTGTLTEDGLDMWGVVPKSS-TNQFQIP------------------LKSVDRLPFDHFLFGMVTCHSITILNGRMMGDPLDLKMFESTGWELEDSNNIPDTEKYGILYPTILRQPRGGLSGMAETESGSKNEIKRQSSVDDLLATVGISPSQKNFDHGIVREFPFTSALQRMSVVTRCLSDQVFNVYCKGSPEMLKKLCKPQSLPDNYSQQLSEFAKKGYRIIAIAFKALSHKMNYTKVQRLSREEVENNMEFLGFVILENRLKPDTTKVINALNAAKIRTIMITGDNILTAISVARDCGIVSPSQSVITVHADPIGDSANIQTNTGTECNFDNSSDKHYKLHYTLDLGSKTSRAYLFKSCFNSNLFDPETPEFTAQVGKTIFHMESTNSLVNESTSSYAESGLPTSDSLASVKTIDTWTHNDAELGIKHTPDESWRRQECIFAMDGKTWQIVKDYFP----EEMEILLTRGSIYARMSPDQKQALVIELQNLDYCVAMCGDGANDCGALKVAHAGISLSETEASIASPFTSRNPTISAVLKVIKEGRAALVTSFGIFKYMAAYSLVQFISVMILYSIDSNLTDKQYLYVDLGLISIFAFFFGKTESFDGMLVEQVPLSSLISSTPLASLLLHLTVVTAFQVTCWVHLHQQPWFKAFEPADEDHLG---------------------------CFENYTMFCISSFQYIILAFVFSKGAPYRKPLWSNWPLCLAFIVNLCIIVYLVLYPSDWVASFFQLIVPPTMRFRYVMLAYGAASFICHIFVESFLVEYLVFKKYQVKREKNWVTSKQKYMRLEHDISNIKNWPPITEVYEPNNLIDCETEQPTYVSLHAEQNHDTQLGKFPGFC------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12697-1", "uniprot_id": "YPK9_YEAST", "id": "Q12697-1", "name": "Vacuolar cation-transporting ATPase YPK9", "aln": "MDIPSSNQIQHGQRSERNRRMPRASFSSTATTSTAATLTSAMVLDQNNSEPYAGATFEAVPSSIVSFHHPHSFQSSNLPSPHSSGNLEQRGRRLTESEPLVLSSAEQSRSSSRNPSHFRFFTQEQISNAEGASTLENTDYDMAWDATPAYEQDRIYGTGLSSRRSSIRSFSRASSLSNAKSYGSFSKRGRSGSRAPQRLGENSDTGFVYHSATHSSSSLSRYTTRERIPIELESQTDEILEDESSTHSLESSDSRRSASENNRGSFSGHDDVHNQHSEYLKPDYHEKFYPQYAPNLHYQRFYIAEEDLVIGIAAYQTSKFWYIIYNLCCFLTFGLVYLLTRWLPHLKVKLYGVKVPLAKAEWVVIEN-EFGEFVIQPIDRQWYNRPLSTVLPFENYPNP--------SYEPNDINLSHHHANEINPNVPILITFEYRYIKFIYSPLDDLFKTNNNWIDPDWVDLSTVSN--GLTKGVQEDRELAFGKNQINLRMKTTSEILFNEVLHPFYVFQVFSIILWGIDEYYYYAACIFLISVLSIFDSLNEQKKVSRNLAEMSHFHCDVRV---LRDKFWTTISSSELVPGDIYEVSDPNITILPCDSILLSSDCIVNESMLTGESVPVSKFPATEETMYQLCDDFQSTQISSFVSKSFLYNGTNIIRARIAPGQTAALAMVVRTGFSTTKGSLVRSMVFPKPTGFKFYRDSFKYIGFMSLIAIFGFCVSCVQFIKLGLDKKTMILRALDIITIVVPPALPATLTIGTNFALSRLKEKGIFCISPTRLNISGKIDVMCFDKTGTLTEDGLDVLGVQISEPNGVRGQKFGELLSDIRQVFPKFSLNDCSSPLDFKSRNFFMSLLTCHSLRSVDGNLLGDPLDFKMFQFTGWSFEEDFQKRAFHSLYEGRHEDDVFPENSEIIPAVVHPDSNNRENTFTDNDPHNFLG------------VVRSFEFLSELRRMSVIVKTNNDDVYWSFTKGAPEVISEICNKSTLPADFEEVLRCYTHNGYRVIACAGKTLPKRT-WLYSQKVSREEVESNLEFLGFIIFQNKLKKETSETLKSLQDANIRTIMCTGDNILTAISVGREAGLIQCSRVYVPSINDTPLHGEPVIVWRDVNEPDKILDTK------------------------------------------------------TLKPVKLGNNSVESLRECN-----------------------------YTLAVSGDVFRLLFRDENEIPEEYLNEILLNSSIYARMSPDEKHELMIQLQKLDYTVGFCGDGANDCGALKAADVGISLSEAEASVAAPFTSKIFNISCVLDVIREGRAALVTSFACFQYMSLYSAIQFITITILYSRGSNLGDFQFLYIDLLLIVPIAICMSWSKSYE-KIDKKRPSANLVSPKILVPLLISVFLVFLFQFIPWIIVQKMSWYIKPIVGGDDAVQ---------------------------SSDNTVLFFVSNFQYILTAIVLSVGPPYREPMSKNFEFIVDITVSIGASLLLMTLDTESYLGKMLQLTPISNSFTMFIIVWVILNYYAQLYIPPSIKG------WLKKKKS-----SKKYKLLIQEEMKLKEV------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .... . :: : : .*: . : .** * : *: * . : .* :*: ::: .:. .: . ..: : . : :. : : : :. . *: . **. * *.:. * * * : :: :*. :**:****** *:: ** * *: *::::*:.* *: : :: . * : .. * : : :***** :.. * **::*:...*:::*.******:**:* * .. .. : : *: **::*:.: .. . *.*:.** *:**.*:**:::* * .:*: *::*:: *:: :. .** : : :* ::: .***.***::*:* :* .*** . ****** :*:.*.*: **************: *. . : * . : .: :***: ::* : *****:***: *.*.:*: . * : : .* * * *:****:.: .: : **:**:: .:* .::* :: : * :: :*:*:** * *:* ::::**:**.:: ***::*::*:** :* .:: *. *.***:* ****: ***:*.::. :: . : : . . . * .:.. :*:.*. :::: . : :* ..:::*****.:* *: ::*:*:* *.:************ *..****** ***:*:****: .*..* .:*:*******:**. *:*:: *. :*** :** . : : *:* *: : ..: :. ..:: : * ..*:*. * .::: . . . :: ::: .*: .: : . : .:: : .:: * *:::* * *:*:*: *: : . : : :: : : : . : : :: .: ::: : :. ..:* :. : . ", "identical_positions": 260, "similar_positions": 358, "identity": "15.58%" }, { "cls_id": "homologset.agr.HGNC:3179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26684-1", "uniprot_id": "EDNRA_RAT", "id": "P26684-1", "name": "Endothelin-1 receptor", "aln": "MGVLCFLASFWLALVGGAIADNAERYSANLSSHVEDFTPFPGTEFNFLGTTLQPPNLALPSNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGEQHRTCMLNATTKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTS-VPMNGTSIQWKNQEQN-HNTERSSHKDSMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61614-1", "uniprot_id": "EDNRA_MOUSE", "id": "Q61614-1", "name": "Endothelin-1 receptor", "aln": "MSIFCLAAYFWLTMVGGVMADNPERYSANLSSHMEDFTPFPGTEINFLGTTHRPPNLALPSNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGELHRTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTS-VPMNGTSIQWKNQEQNNHNTERSSHKDSMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25101-1", "uniprot_id": "EDNRA_HUMAN", "id": "P25101-1", "name": "Endothelin-1 receptor", "aln": "METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTS-VPMNGTSIQWKNHDQNNHNTDRSSHKDSMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P7F8-1", "uniprot_id": "A0A8M1P7F8_DANRE", "id": "A0A8M1P7F8-1", "name": "Endothelin-1 receptor", "aln": "--MTAFRILLLMMTSSCLLIG---RGSCQSNSSAASGRRDPGGSSGRVTSDLRAR--PLPP------ACLRRTYMEGVFKYVNTLLSCAIFVVGIVGNGTLLRIICQNRSMRNGPNALIASLALGDLIYITIDIPINVYKLLAMRWPFDDSVFGLFLCKLMPFLQKASVGITVLNLCALSVDRYRAVASWNRVQGVGIPVSTALEIICIWLLAVVLAVPEAIGFKMVSFEYNNVTIRTCMLKPETPFMTFYRDVKVWWLFGFYFCVPLLCTAVFYTLMTCEMLSNRKGSLKFSLSEHLKQRREVAKAVFSLVLIFALCWFPLHLSRILKKMVYFQNDVGRCDLLNFLLVFDYLSINLATINSCINPIILYFVSKKFKNCFRSCLCCWCYSDGSLMGSGAPLNATSLQYKSPEHN-------QRKDSYN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : . : . * * : .. . * . . : : :. **. * ::* : .***:**::**:**:**:***.****** **:.*******************:.**:****:**** *****.. **:*****:*****:***********************.****:***: **:**:.**:*:.:**:****** **.***.. :****:. : ** **:*** *********:**:***:**********..*:***:::*************:**.**:***************** ** : * .**:**.***::**:.*****:******* ************:***** *:.. *** * .*:*.**:*:*. ::* .:*** *", "identical_positions": 255, "similar_positions": 94, "identity": "59.58%" }, { "cls_id": "homologset.agr.HGNC:31791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LR17-1", "uniprot_id": "A0ABK0LR17_RAT", "id": "A0ABK0LR17-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MLPWRRNKFVLVEDEA-------------KRKAKSLSPG--------------------------------------LAYTSLLSSFLRSCPDLLPDWPLERLGR-----------------------VFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKG-DGCTDDAVGRIWARCGPGGGTKMKLTLGPHGIRMQPSER-GSGGSGGRRPAHAYLLPRITYCAADGRHPRVFTWVYRHQARHKAVVLRCHAVLLARAHKARSLARLLHQTALAAFSDFKRLQRQSDARHVRQQHLRAGGAAASVPRAPLRRLLNAKCAYRPPPGERSRGAPRLSSIQEEDEEEDAEEEDAQDSEGGALQRERP---EVLSLARELR-----------------TCSLRGAPAPPPPAQPRRWKAGSRERAGQAR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AM80-1", "uniprot_id": "A2AM80_MOUSE", "id": "A2AM80-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MLPWRRNKFVLVEDEA-------------KRKAKSLSPG--------------------------------------LAYTSLLSSFLRSCPDLLPDWPLERLGR-----------------------VFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKG-DGCTDDAVGRIWARCGPGGGTKMKLTLGPHGIRMQPSER-SSGASGGRRPAHAYLLPRITYCAADGRHPRVFTWVYRHQARHKAVVLRCHAVLLARAHKARSLARLLHQTALAAFSDFKRLQRQSDARHVRQQHLRAGGAAASVPRAPLRRLLNAKCAYRPPPGERGRGAPRLSSIQEEDEEEDAEEEDTRDSEEGALQRERP---EVLSLARELR-----------------TCSLRGAPAPPPPAQPRRWKAGSRERAGQAR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZT52-1", "uniprot_id": "FA43B_HUMAN", "id": "Q6ZT52-1", "name": "Protein FAM43B", "aln": "----------------------------------------------------------------------------------------------------------------------MLPWRRNKFVLVEDEA-------------KCKAKSLSPG--------------------------------------LAYTSLLSSFLRSCPDLLPDWPLERLGR-----------------------VFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKG-DGCTDDAVGKIWARCGPGGGTKMKLTLGPHGIRMQPCERSAAGGSGGRRPAHAYLLPRITYCTADGRHPRVFAWVYRHQARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFSDFKRLQRQSDARHVRQQHLRAGGAAASVPRAPLRRLLNAKCAYRPPPSERSRGAPRLSSIQEEDEEE--EEDDAEEQEGGVPQRERP---EVLSLARELR-----------------TCSLRGAPAPPPPAQPRRWKAGPRERAGQAR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHA6-1", "uniprot_id": "Q9VHA6_DROME", "id": "Q9VHA6-1", "name": "PID domain-containing protein", "aln": "MAANNGNKFSMEHDSEGCDEVDFIVATHNNNNDYEDLGSVSQAVINTKVAAAAATAAAATPNNEPNSNTLKKAKERRTLFHFGSNKKLSQSKSQESQEAGSKDATPATTAAPLPPVPIGTPPRQHKFVKSNSLARLLGNTYNAKKFEKQEQKRLASGSEGGKFNTYSGRRGRAGPYLERFKRVSKEDGDVAGEDDTVRVTNVITLTTDSRDLLYGSRQEHVGRTGGYDQNDQLTSKAYRTLTRSLGKLWRRTHSVDISTPDPEFKVSYLGNVLTGWAKAGEGCVEKQLNTLWRNYTQHSKPDVIMRLKVCASGLKATTR--------QHGLTEYWAHRITYCCAPKNYPRVFCWIYRHEGRKLKHELRCHAVLCSKEKIAQDICDTLRENLESALREFKREKILKQN--ARLSLANAVYDNPSLPRR--KIMLSVGGNNYRPPLERSKSAPKLMAIEEAIGEEEGDEIEDTNEPEMMPCCQKDSLYPAMTLGRRRCRRGHSIRRTGKIQSFSPCCSSHMAKELPQEETKTMAAAGSSANDGSDSDDFEKLLKFDTTLSNELLPYFDMQLHKNSSQSMVSLSELKEEEGEPLSLLPTINSDPSADPEADYNAEDHDVTAPRRSGVCSDGEEDFLDDADDHYFRHAAMLTMLHRSSMRKMRAADQTSLKYRHQTQSSISSNASSSTTASTSAAAGGGSAQQGLTSPDSDEGSISSGCETASTVTNANHEEYNSKRVSDPGQLEQSPDLELEQAQVLEQMMIYQRLEQQLRKNSGDATNYSSSSSITLKRSNSGSDKQERSDHPDDDNSDSDESGYVEFQEKERPGQQPLISEASVTLAKIATVKPQVPPKPAPRRSLSLNAVATGASAGSSAGKAPGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *::*** :. * * : * *:.* . .: : :: .. *** . *::** : * :.*::.. ** :.* ****.:* **. :**.:. :. :* . . ..: : * . ::. * :: * ***** * .:**** *:***:.*: ******* :: : *: :. *::. :*: :*** : .: .* . .* .*:** : :*.. ** **.:.**:* :*:* ** :* : :. :: .::*.*. ** : * * **. . *. ", "identical_positions": 89, "similar_positions": 100, "identity": "10.14%" }, { "cls_id": "homologset.agr.HGNC:31792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RC54-1", "uniprot_id": "M0RC54_RAT", "id": "M0RC54-1", "name": "", "aln": "MATNPQPQPPPPAPPPPPPQPQP--PPPPPGPGAGPGASGPGGAGAGSGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEETAGSTAPDDEKLESSVITQGAPAPGPSANVASDAMSILETITSLNQEANAAARASTEMSNAKASERISRKLSSQPSTDISTDKERGSEDGAEREKVTPDSGGEGLETAPKSEEPNDLPCPVEETKNHTKEN-SLLFLSKDAQQENSDPKIKSTDKGEKKPDGNEKGERKKEKKEKTEKKIDHSKRNEDTQKVKDERQAKDREAESTKLPSEKISSRARAAEGTKEDCSLVDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVMSESMEEGEITSEDEEKNKQNKTKAQTSDSTDGKARSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRRINREKLEEKRKQKAEKTKSSKAKSQGKSSVDLEDSSTKTLEPKAPRIKEVLKERKVLEKKVALSKRRRKDSRNADESSKKKPQAEEESKEALKTSEHCEKEKASS-KDLKHTHGKGEPNRPARRLSESLHSVDDNKTESKVEREYKRRTSTPVVLEGAQEETDSRDGKKQPDRSEINMEETQKQKSTLKNEKYQKKDDPET-HGKGLPKKEAKSAKERPEKEKAQSEEKSSSKHKHKSDSVHKVGDETEPHSSEKS-EAEESVRKQSQQTKLSSDDKTERKRKHRNERKLSVLGRDGKPVSEYTIKTDEHARKDN-KKDKHLSSEKTKAEHKSRRSSDSKLQKDVLSSKQHSVTLQKRSESCSEDKYETDSTNADSSSKPEELLHKERRRTKSLLEEKLVLKSKSKSQGKQIKVAETESQEGVTKQVTTPKPDKEKNTEDNDTERQRKSKLEDRTCEEAVAEPALESAVPSAHSSQKDSGHRAKVASVKEKHKTDKDSTSSKLERRVSDGHRSRSLKHSNKDVKRKEENKPDDKNGKEVDSSHEKGRGNGPVTEKKLSRRLCENRRGSTSQEMAK-EDKLAANLSGTASTSSLQRPKKSTETALIPEQEPMEIDSEAAVENVSELSKTEDISSNSSQQDTDFENVTKHKAAAGVLKDELRTSMVDSKPAAAVTCKSGRGLTITSNSEKHADHKSTLTKKVHSQSTASKATPREREPAQRGAQEISVDSEGSRKVLSRALSENEKGQKNLKGVSKTTEECGTHRNASLEFSTDSDLLSSLGSVSVVPQKESHDSSTITVVDREAISEGGKASTSLVNHSDIPNQNLAVKKSEILKTNGSKEGNDGFTVDILAKANGSGKRHLSEDSQAMLLCSKEGKVGIALAGKPSGVIGENKSISKQRSLMGTAKKESDLNVDPDVKQ-----------DSAAGEHVVDLTTRKEAETIRRKHNKDPDESKKIPTDIERKTENSEVDTSARRDSAP-VPQQRHGKMERGAAGSGRRDKSFIATSTEGTDKGIMLNTIKAGDATTTSSETGGKGVALPCTSIEADEGFIMGACPRNNPLQVGAEASECTVFAAAEEGKGVVTEGFAESEILLTSSKEGESGECTVAESEDRVAGPLTAHTVQAETNVNSITTEEKDDAVTSAGSEEKCGGSSCA----VEGTATFVGEVESDGAVTSAGTEIRAGSVSSEDVDGSQENRIQVGPKKETEGTVTCTGAKGRNDNFVFCLVTGAGTQEQRVVTGADVVQENDDKSLEASANQ-GDGSGTDGTEGESAVTSTGITEEDGEASANCTGSEDSTEGCAISSETEENAESAMDSTEAKDMTNTPLVATGPCDDEGIVTSTGAKEEDEEDEGVVTSTGRGNETGHASACTGIEE-SEGMLVCESGEGGGPIGPTMDHVDAEAGAAAMNTNDSNVDSMSGAEKEIKDTDICSSAKGIVESSVTSAFAGNSDRPPVLESSENPMASATSHHSDSQLTRKETVEDTTISTGLVRGSDDVLLSGAVPEYEVGHMSPRE-----------NEECDGLMASTASCDVSNKDSLAGSKSQGNGLVIPTS-TNDCTPPISAVIDVRGGHSCTLSTEENRNDARVHMEGFEAPMPSAISDEKSQLTASRSEEKDECAMISTSIGEEFEVPISSAVTITCAERQQPVAA-VEESTTGPALVSTEDFEIPMPSAPTEAESPLASTSKEEKDECALISTSIAEECEASASGVSRNAP----------SDGNAVISTSSVEDCEGSVSSAVPQESVCPSVVPVEETGDTAMISTSTSEGREAVMVGTIPTDEDQASTVRGEDLSDAAIISTSTAECVLTCTSLSRHEESQQASTHNPRGNGGRLVTKQSKCELPMPSLMTESNCKCPGPFTTGKGVGPLMAVSTRGEHDRLPVCEPSAGQSQPGTALCLGEEKSHGMDCPGQD--------------LNAKERNTLLSCVQRESKSVEAEAAGDSSTASGIVRKDSERNANSLSETNCLRRPEQKSAEDSSGSIHCLAAVNTG-AKTDNMLPITDAASECPS---DQQEPENNLKA-TTKCITGQESKMPSSHTAVLPSVCRVAPSAPKREGGLPAKSDHSGTWTSEGSAEKMGHVAGARQSYHREGNLDVTIPPEDNGCGIGNEELPPKGIEGSELSANLTTEISVSSEEDTNHGVVAAPENPCVGRPSGAAELQVEALLMSESLNVENSESRINEEIHYDSRNKEEISCGRKDSTEALSGCSAEADPEEVEEEERHISKRNRKQDYSSEEEELDDSPDVLDSRIQTAQRQCSETEPHDTKEENSGDLEEFSTLNSKANSSPA--LEDRDEFSSSEGTGEKIEPNEDDGSVKSQEDDQPIIIKRKRGRPRKYPAETAFKSKEDSKTETDITTVEQSPPGDKLKVSQADEFNKETTDLQEKSTSNDDNEEKTGS-VRRRGRKPKRSLTSSDDAESSEPERKRQKPFSETSEDKNDQDSDEEEEEEDEDEPLGATTRSATRSEAQRKNHSKPSTRATSKLGIPETVSPRNRQKLAKEKLSTSEKVSKSPPLGRSKAQLSPSVKRKRELSPPGARTRGQQKVDETPLKKAKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6J5-1", "uniprot_id": "BD1L1_MOUSE", "id": "E9Q6J5-1", "name": "Biorientation of chromosomes in cell division protein 1-like 1", "aln": "MATNPQPQPPPPAPPPPPPQPQP--PPPPPGPGAGPGASGPGSAGAGAGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEAAGSTAPDDEKPESSVITQGAPAPGPSANVASDAMSILETITSLNQEAN-AARASTEMSNAKVSERTSRKLSSQPSTDVSTDKERGSEDATEREKATSDSGGDGLEAALKSEEPSDLPCPVEETKNHMKENNSLLLLSKDAQQESTDPKIKSMDKGEKKPDGNEKGERKKEKKEKTEKKIDHSKRNEDTQKVKDERQAKDKEVESTKLPSEKSNSRARAAEGTKEDCSLLDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVVSESMEEGEITSEDEEKNKQNKAKVQPGDSSDGKARGVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRRINREKLEEKRKQKAEKTKSSKVKSQGKSTVDLEDSSAKTLEPKAPRIKEVLKERKVLEKKVALSKRRRKDSRNVDENSKKKPQAEEESKEALKTTEYCEKEKASS-KDLRHTHGKGEPSRPARRLSESLHSADENKTESKVEREYKRRTSTPVILEGAQEETDTRDGKKQPERSETNVEETQKQKSTLKNEKYQKKDDPET-HGKGLPKKEAKSAKERPEKEKAQSEDKPSSKHKHKGDSVHKMSDETELHSSEKG-ETEESVRKQGQQTKLSSDDRTERKSKHKSERRLSVLGRDGKPVSEYTIKTDEHARKDN-KKEKHLSSEKSKAEHKSRRSSDSKLQKDALSSKQHSVTSQKRSESCSEDKCETDSTNADSSFKPEELPHKERRRTKSLLEDKVVSKSKSKGQSKQTKAAETEAQEGVTRQVTTPKPDKEKNTEDNDTERQRKFKLEDRTSEETVTDPALENTVSSAHSAQKDSGHRAKLASIKEKHKTDKDSTSSKLERKVSDGHRSRSLKHSNKDMKKKEENKPDDKNGKEVDSSHEKGRGNGPVTEKKLSRRLCENRRGSTSQEMAK-EDKLVANMSGTTSSSSLQRPKKSTETTSIPEQEPMEIDSEAAVENVSELSKTEDISSNSSQQDTDFENVTKHKATAGVLKDEFRTSMVDSKPAAAVTCKSGRGLAVTSISERHADHKSTLTKKVHSQGNPSKAAPREREPIQRGAQEVSVDSEVSRKALSRAPSENEKGQKNLKGMSKTTEECGTHRNASLEYSTDSDLLSSSGSVTVVPQKESHNSNTIPVIDREAISEGGRASTSLANHSDVPNQYSTVKKSEVHKTNGSKEGNDGFTVDMPTKANGGSKRHLSEDSQATLLYSKESKISIPLADKSMSVTGDNKNINKQRSLMGTAKRESDLKVNPDIKQ-----------DSAAGEHVVDLSTRKEAETVRRKHN------KEIPTDVERKTENSEVDTSARRDSAP-VPQQRHGKMERGAAGSGRRDKAFIATSTEGTDKGIMLNTVKTGDATTTSSEVGEKGTALPCTSIEADEGFMMGACPKKHPLQVGAEASECTVFAAAEEGKGVVTEGFAESEILLTSSKEGESGECAVAESEDRVAGPLAAHTVQAEANVNSITTEEKDDAVTSAGSEEKCGGSACT----VEGTATFIGEVESDGAVTSAGTEIRAGSLSSEDVDGSQENRIQVGPKKETEGTVTCTETKGRNDNFI-CLVTRVETQEQRVVTGADVVQVNAAKPQEANANQ-GDGSGTDGAEGESAVTSTGITEEDGEASANCTGSEDNREGCAISSETEESAESAMDSTEAKDITNAPLVAAGPCDDEGIVTSTGAKEEDDEDEGVVTSTGRGNEPGHASACTGIEE-SEGMMVCESGEGGAQIGPTIDHVNAEAGAATVNTNDSNVDSMSGAEKEIKDTNICSSAKGIVESSVTSALAGNSDRPPVLCGSEGPMASASSHHSDSQLTRKETVEDTTISTGLVKGSDDVLVSGEVPECEVGHMSPRK-----------NEECDGLMASTASCDVSNKDSLAGSKSQGNGLMISTS-TNACTPQISAVIDVRGGHLSTLSTEEIRDGVRVHREGFEAPMPSAVSGENSQLTASRSEEKDECAMISTSIGEEFELPISSAVTVTCAERQQPVAA-VEESTTGPALVSTEDFEVPMPSAPTEAESPLASTSKEEKDECALISTSIAEECEASVFGVSRNAPSV--------TDGNAVISTSSVEDCEGSVSSAVPQESVCPSVIPVEETGDTAMISTSTSEGREAVMVGTIPTDDDQATTVRGEDLSDAAIISTSTAECVLTCTSLSRHEENQQA-THNPEGNGGHLATKQSKCELPMPSLVAERNCKCPGPFRMGKGVGPLMAVGTRGEHDRLPVCEPSVGQGQPGTALCLGEEESHGMDCPGQD--------------LNAKERNTLLSSVQRESKSAEAEAAGDSSTARRTVRKDSERNANSLSETNCLREPEQKPAEDTSGSTHCLTAVNPG-AEADGMLPITHAALEYP----DHQEPESNLKT-TTKCITGQESQMPSSHTGVLSAVCHVAPCASEQEGGLPTKSDHSGTWTSEGSPEKMGHVAGARQSFHREGNLDVTLPPEDNGCGVGNEESPPKGIGGLELSTGLTTEISVSSEEDTSHGVVAAPENPCVGRRRGAAELQMEALLMRESLNVEKSESRINEEIHFESQNKEEICCGRKGSTEALSGCSVEADPEEVEEEEKQISQRNRKPDYSSSEEELDDSPDVLDSRIETAQRQYSETEPHDTKEENSGDVEEFSSVTSKTNSSTG--LEDRDEFSSSEGTGEKTEPNEDDGSIKSQEDDHPIIIKRRRGRPRKYPAETAFKSKEDSKTETDITTVEQSSPSGKLKVSQADESNKEIANLEEKSTSNDDSEEKTAS-MRLRGRKPKRSLTSSDDAESSEPERKRQKSVSETSEDKKDEESDEEEEEEEEEEPLGATTRSATRSEAQRKNHSKPSTRATSKLGIPETISPRNRQKLAKEKLSTSEKVSKSPPLGRSKAQLSPSVKRKREVSPPGARTRGQQKVDENPLKKAKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFC6-1", "uniprot_id": "BD1L1_HUMAN", "id": "Q8NFC6-1", "name": "Biorientation of chromosomes in cell division protein 1-like 1", "aln": "MATNPQPQPPPPAPPPPPPQPQPQPPPPPPGPGAGPGAGGAGGAGAGAGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEGSGNTAPDDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEAS-AARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDSEN-MKQKTSATVQKDELRTCTADSK-ATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNLK--NTAAEEHVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPDVIPLFDKRTVLEGSTASTSPADHSALPNQSLTVRESEVLKTSDSKEGGEGFTVDTPAKASITSKRHIPEAHQATLLDGKQGKVIMPLGSKLTGVIVENENITKEGGLVDMAKKENDLNAEPNLKQTIKATVENGKKDGIAVDHVVGLNTEKYAETVKLKHKRSPGKVKDISIDVERRNENSEVDTSAGSGSAPSVLHQRNGQTEDVATGPRRAEKTSVATSTEGKDKDVTLSPVKAGPATTTSSETRQSEVALPCTSIEADEGLIIGTHSRNNPLHVGAEASECTVFAAAEEGGAVVTEGFAESETFLTSTKEGESGECAVAESEDRAADLLAVHAVKIEANVNSVVTEEKDDAVTSAGSEEKCDGSLSRDSEIVEGTITFISEVESDGAVTSAGTEIRAGSISSEEVDGSQGNMMRMGPKKETEGTVTCTGAEGRSDNFVICSVTGAGPREERMVTGAGVVLGDNDAPPGTSASQEGDGSVNDGTEGESAVTSTGITE-DGEGPASCTGSEDSSEGFAISSESEENGESAMDSTVAKEGTNVPLVAAGPCDDEGIVTSTGAKEEDEEGEDVVTSTGRGNEIGHASTCTGLGEESEGVLICESAEGDSQIGTVVEHVEAEAGAAIMNANENNVDSMSGTEKGSKDTDICSSAKGIVESSVTSAVSGKDEVTPVPGGCEGPMTSAASDQSDSQL---EKVEDTTISTGLVGGSYDVLVSGEVPECEVAHTSPSEKEDEDIITSVENEECDGLMATTASGDITNQNSLAGGKNQGKVLIISTSTTNDYTPQVSAITDVEGGLSDALRTEENMEGTRVTTEEFEAPMPSAVSGDDSQLTASRSEEKDECAMISTSIGEEFELPISSATTIKCAESLQPVAAAVEERATGPVLISTADFEGPMPSAPPEAESPLASTSKEEKDECALISTSIAEECEASVSGVVVESENERAGTVMEEKDGSGIISTSSVEDCEGPVSSAVPQEEGDPSVTPAEEMGDTAMISTSTSEGCEAVMIGAVLQDEDRLTITRVEDLSDAAIISTSTAECMPISASIDRHEENQLT-ADNPEGNGDLSATEVSKHKVPMPSLIAENNCRCPGPVRGGKEPGPVLAVSTEEGHNGPSVHKPSAGQGHP-SAVCAEKEEKHGKECPEIGPFAGRGQKESTLHLINAEEKNVLLNSLQKEDKSPETGTAGGSSTASYSAGRGLEGNANSPAHLRGPEQTSGQTAKDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQQGSEDNLKTSTTKCITGQESKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQASAEKTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLKMEAYVPSEEEKNGEILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDD-TIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQR-----------------------------------------------SKTQLSPSIKRKREVSPPGARTRGQQRVEEAPVKKAKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8C2-1", "uniprot_id": "A0A8M3B8C2_DANRE", "id": "A0A8M3B8C2-1", "name": "", "aln": "------------------------------------------MAALHPGDPQLVSVIVNHLKTEGLFDQFRR-DCLADVDTKPAYLHLRQRVDNFVSNHLANHTWSPQLNKNQLRNSIRQLVQQSGMLEQGVDRIVAQVVDPKVHHTFRPQVERIVRRFLSPHSHLEEEE---------------LPAVAPPLPAEHLEAEVLIQDDAAVSWSADVQMSESAGAESN------------------------------------------------LELSVEEMDISLPEEEEELQLKEEEPLLEEEEQPQVKEEEPHVKEAELETQEAVLKEEPKEEADASKETSSKSSGKSREENPETDSQK----------------PTSVKQKTRERLREEYSLEDSD-LEGLSDITVSSVHTSDLSSFEGDSEEDEAPSESTEEGEISSEEDGGRK------TPADGSDRKPRGVRQGYVHKPFLYSRYYSDSDDEVTVEQRRRSVAKEKEERLLKRQQNRERMEEKRRLRAAQREEQERKKQASVCADAR-----------PRAKEARKEKKFLEKKVALSRQRKRDSRKEDDRKRSDTEGDSLNKEVKPAGQRSGR------------------------------VDEQRRKKSDTEEKLCDRNRVHSFILDLESGTEER--------------------------------------------QRTKTARKEVHLKDKERKDEHKLKHKLKMDSRKSTDTDEKDGGAGKG------------------GAEEKKGSKVKPDRKSSVTSKDT--------KTPEAADEANLKKGKMAADAKDKEKPKTSGKSESKLLR------------RLDSTGSSEERSEVETG--------SEVNRKKDKHPKEMLKR--------------------------SKSHPEPHPEARPGEKLKVRADRRDSSVDKTQAQKSGSEPEGD----------------------------GRKPETSLKSKTLLEKHRSKSQNPAGGKPERKTEAKSKPAEDK---------REEKKTSEEKLRDTKVRKLKVQKDSKFEE----------------------ESLDSAAVSSSTPVSDDPFAALSDVTPESEDEEVEPKEPRPLSAEADALLSLMDISVRRDVEADMKMQEAALTLLSMGPDAGRSSDVVAADDQVAMQTVATDPEDAGSLPECAAADAAAPAATVEPMETESLRLQEVTSQSGDE---------------------------------------------QKEERDTHTHTTDTAQTLSADTAEPTLENTAADEPMQTPSADAAEPLEPVTAAEPASPVTEDAAEQRQTSS----ADETPAQTLPKHTAETHTPTTVNPAEPTAESAQMEES---------------------------------------------------------------------------------------------DEPEPVQILSAGTAESAQTHAAEEPAQTHAADEAESAQTLTADTESAQTRNADLNEPVLKMNADQAEHVQTHS--------ADDAECVQTPTAET---------------------------------------MRIYNADADVPAQTIHADEAESVQTPT------------------------AETDEPVETADADTSEPAQTLTADEADSAQTHIADTEP-------------------------------AQTLTADTVKTLNADEAEPVQTVDQDETVQMVDADEVESAQTLT----------------------------TETDGTAEMDNAEPAHTLTANEAEHELTADEAKSAQTLTADEADSAQTLTADEAKS-------------------------------AQTLTADEANSAQTLTADEAESVQTLTADEADSAQTLTVDEAK---------------------------------------------------------------------------------------------------------------------------------------SAQTLTADEADSAQTLTADEADSAQTLTADEAKSAQTLTADEAKSAQTLTADEAEHEQTLNADEA--------DSAQTLTADEADSAQTLTADEADSAQTLTADEADSAQMLTADEAESAQMLTADEAEHG------------------------------------------------------KTLNANEAESAQMLTADEIKTDRMLAADTDEPAQTLTAETAAP---------------------------------------------------------------------------------------------------------PSSSGEQESAAAAAEDEDGD------------------------DDEEDTRVSRTPRRGRSSRAAEAPQRETRSASQPKEVEP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVEEEPKEQSRRGR--------------------RSAAQTRDTPAVKPALKRKRSDEELKEDPEPSAKHRRDAVSPAGDQDASKASDEEEERKEEEEEETTEDQQRK------PARRGRPSK-------------------------------ASSATDDSDTGASEKRDGEKEEDEEEEKKSR--------ATTRAASRLEAERNKPSKPSTRALSKLSKEENTPHTRSVRG-------------------------------------------------------------------------------RKRDPSPPVSRTRGGQKSEDPAAKRAKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHZ9-1", "uniprot_id": "A0A0B4KHZ9_DROME", "id": "A0A0B4KHZ9-1", "name": "", "aln": "-------------------------------------------------MDDFIKTLIAEVKSQGVFDEFRFNCCLADVDTKPAYQNVRTQVETAVNDFLAKQQWTPETNKVQLRERLRKHLMDSDVLDKGVDQIVDQVVNPKVATIFEPKIESIVYKYLG---------------------------ITPPARPTMLSAPPLPPFGAHLNGSSLLN----------------------------------------------------------------------------------------------VETTVGLLPTDLEQISPDSDRATVKSESRDDELPPGVDDEDTSPSYELVSER--------------------KTLAIKEELNNVSLNNSDSVNGVSQASQLSQVSSDSRLTMASSTESMVDSHQHTAAHNSGEPENICEEAQMPKFSENSWDASAGTGRSEGRQLHFDIKQDAITFEG----TERKNSVSETTSTGLQILSIEDEIMSEVKANIDDANNASIESIAPEP------------------------VQVPAPPKVNPPPPPRPASPKVEPPPPAPPGVESPPGPQPPASPRFDP-------------------------------------PPPHTIEPPPPPAPPTLVP--------------------------------------------------------PPPPAPPTIKPPPPPAPPTVEPPPPPPPAPPTVEPPPPPPPAPT-----------------------KVEPPPPPAPAEVEPPPPPAPTELEPPPPPAPPKVELPPPPAPPKAEAAITPRRAKGSNG----------------------------------------------------------------------------------FITELAVTPKESETRDKPHNVNTDVKEDEQPATTEDKQDKPLELG---------------------------LDAPKDAVSTASESTESPTSTSSQSKSHSKSRDKEKEKD--------------RRHHRHSDDKHRRRSTDRDRDRSRD--------------------------KSHSKHSSSSSSKHSSSNSSSSKHKSSSSKNDKSSSSSSSRSNRESSSSKRSGTTSSSRHESSSHKKHKSSSSSSRSERDKGKEKDKEREKDSQSRSHHSSSSSSSSSRRKDHDRGRD---------------------------------------------------------------------------------------------RDRNKSNTSGSAENKAIHDDHSESKEKYKQRRGSDSNDEGKPPSSGGPAKNSQPEDSAATMKSDAPVENANGTNGNSNGSTN----------------------------------------------------------------------------------------------------------------GACDNVSGVVIVSDILQQSTSSFVELTAGSQSHDRAESSKHEPED--------------------------------------------------------------------------------IDGKEADNQPEKTELEARQ------------------------------DECASQNEVPTVEPQTLADSVPDLPAKESMDTLE-----------------------------------DEKVETNVEENKSEEESKPENPPEECVDEPAQVGDVED----------------------------------------PPQDADKPATPVPISNEQSDEFSADFVTHFEENTDEFRTRLQLIN-------------------------------------------------QLIEDRKNLLNRLSEDGTQEEAVDIR----------------------------------------------------------------------------------------------------------------------------------------------ALRRSLSKRRRSSMQEQHRVERETTPPQPRSPSSSSTAGSPAKRLRQDEPKSS---------------PTPSDASINSKENEALEKQEHADALSARRLSKKLCQQQRYTNDDLYKPRPILSQRSRRRGLDSIL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :: .:*::*:**:** *********** ::* :*:. * :.**.: *:*. ** ***: :*: : .*.:*:.*:*:*: ***:**: *.*::* * .:*. ..* . : : : . . . . : .. .. .. . ..: . .. . . : .:. : : : :: ** :** ::*::: : * :** .: *. . *.. .. :.: : : . :. : .. * : : .: :. :*:.*::: .. * : * :.* : : . . : ** . : * : : :. : . : .: .. : . : . : .* . : : . : : *:. :. *: . . : :. . :: . : : * * : . . .:. * : . * . :.* . : . :* . ... . . .. .. *: :. ... . :. .. : . * . . :.. . : . . : :* : . . . . . .: * : : *. . . . : :: . : :. : : * . .. . .. * ::. .. : : : :.. .: . : . * . : :* : . . :: :: . :: . : :: .:. . : : . . * ::.. * : :. * . . : : . .:. ", "identical_positions": 86, "similar_positions": 301, "identity": "2.76%" }, { "cls_id": "homologset.agr.HGNC:31793", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUV8-1", "uniprot_id": "A0ABK0LUV8_RAT", "id": "A0ABK0LUV8-1", "name": "", "aln": "MGVAKSWGGTCSAEPGKRRKMAAVVAMDTQLMLGVGLIEKDTNGEVLWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETIILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWSILHSYMHLHAEELEGLQMCTGYIAGFVDLEVSNRPDLYDVFVNLADSEIIIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEASDAG-KVFLNVEALKQKRFPPATENFLYHLAAAEQMLKADSYFIHGSLSSPLGAALLSVRLRAPGTVGTEASLLHKCCWEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8N2-1", "uniprot_id": "DEN10_MOUSE", "id": "Q9D8N2-1", "name": "DENN domain-containing protein 10", "aln": "--------------------MAAVVAMDTQLMLGVGLIEKDSNGEALWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYMHLHAEELEGLQMCTGYIAGFVELEVSNRPDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEVSDDGGKVILNVEALKQQRFPPATENFLYHLAAAEQMLKV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCE6-1", "uniprot_id": "DEN10_HUMAN", "id": "Q8TCE6-1", "name": "DENN domain-containing protein 10", "aln": "--------------------MAAAEVADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESHVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E7G4-1", "uniprot_id": "DEN10_DANRE", "id": "A8E7G4-1", "name": "DENN domain-containing protein 10", "aln": "-------------------------MATPELMLSLGLIEKDVNADTLWVWCYPSIDADLREVMLRKCCLTLDNQVLHTFVFGQFCRTWYYITTVEVQEPTVLKKVTHFSIVVTAKDFNPEKYAAFSRVLCRTYMKHGSPVKMMEGYIAVLTKGICQSDENGSFLIKDYDVRKALLAGSLKDVVSQFGMETIILYTALMLKKRVVVYHPRIEALLEFTRALPCLVWHRKDWSILHPFVHLENDELENLKVCTGYVAGFVDPEVKDRSDLFDVFVNLPDSEITVSQNAKEAMSMGKLHKEIGNFIVQAAEDADRSDAQVIKDISVKTKEILSNLMSLADHADNS---KLTLECLKQGHYPPATENFLFHLAAAEQLLKI------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:***.:****** *.:.******** * **:::******* :*::**.*****: ***:*:**:** :.::**********:*************:*:*** *:*:********.************:****** :*:* *** ****:**:********:**:********:*****:***: ****:**.*****:**:***.::**. :*** *::****:****: **.:*.**:******.:*** :: *****:*******:*::***:***.::*:::**:**::**:**:::* .::: : . *.:*.*** ::********:*******:** ", "identical_positions": 231, "similar_positions": 90, "identity": "55.13%" }, { "cls_id": "homologset.agr.HGNC:31795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC40-1", "uniprot_id": "NCBP2_RAT", "id": "B1WC40-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYREDYDAGRGGYGKLAQKQ----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ49-1", "uniprot_id": "NCBP2_MOUSE", "id": "Q9CQ49-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYREDYDAGRGGYGKLAQKQ----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JGR6-1", "uniprot_id": "NCBP2_DANRE", "id": "Q8JGR6-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MS-IKLNALFSDSYVDVSQYRDQHFKGNRYEQEKLLKQ------SATLYVGNLSFYTTEEQVHELFAKCGDVKRIIIGLDKIKKTACGFCFVEYYTRADAENAMRFVNGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRQDYDPARGGYGKMVQKS----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3L6-1", "uniprot_id": "NCBP2_DROME", "id": "Q9V3L6-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "--------MFAS--VELSSYRDQHFKGSRSEQERSLRD------SCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKYKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGRGKTGGQVRDEYRTDYDAGRGGYGKLLSQKI------------APNTDNR--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6PVI3-1", "uniprot_id": "NCB2L_HUMAN", "id": "A6PVI3-1", "name": "Nuclear cap-binding protein subunit 2-like", "aln": "MS-KDLKILCKDPALELSCYRDHQFSGRKFQQEKLLKE------SSTLNMGNLSFYTTEEKIHELFSRS-DIRNIFMGLDKIKKTACGFCFVECHNRADAENAMRFLTGTCLDEWIICTDWDVGFREGQQYGRGKSGGQVRDEFREDFHSGRGGFGRQTQI-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08920-1", "uniprot_id": "NCBP2_YEAST", "id": "Q08920-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSLEEFDEVKYDHSTKRLDTPSRYLLRKARRNPNGLQELRESMKSSTIYVGNLSFYTSEEQIYELFSKCGTIKRIIMGLDRFKFTPCGFCFIIYSCPDEALNALKYLSDTKLDEKTITIDLDPGFEDGRQFGRGKSGGQVSDELRFDFDASRGGFAIPFAERVGVPHSRFDNSSSQSNTNNYIPPPDAMGTFRPGFDEEREDDNYVPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .: : .: . *:. *.*: :*******:**:::***::. :: *.:***: * *.*****: :* *::::..* **: * * * ** :*:*:***::**** ** * *:...***:. ", "identical_positions": 52, "similar_positions": 47, "identity": "25.0%" }, { "cls_id": "homologset.agr.HGNC:31796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3P1-1", "uniprot_id": "TCHL1_MOUSE", "id": "Q9D3P1-1", "name": "Trichohyalin-like protein 1", "aln": "MPRLLRGVFCVVEIFHKYAIEDGGNQATLTRTELRQLLEGEIGDFLQPHVFHAVERKLNLLNFDRDGTISFEEFVLAIFSLLNPSYFDIS-LLNSEPRLMSKSEK--IDAVDLGAIGGNIQQVVGVGPTQERLIFPSEMASSGQPSNEEGEVGDEPMVSPCEDIKTHSLPRNVSEPNDPENQQPK--EDAQEVAQNVPATEYDGVQFKRNTVVEVPKQSTSPT------QEIPRERSKPSRRLSDTKISDHM-----------------IQRPTEDE------EHTSTTQDPFLQKRDKATGSENTDLSVVAATRKSSQTQEIFEPMDDTKLSEAQETGKDAGRIPPETN-LEEPKADAKVAESHGLPAQEREHNTRDQSVQSRSRNVSETSSRGEQEGE-----------WKEHERITLSPTADAETQDEKCQEFPGSWRENDAKKDSAAKDPSSEEGNQNLPEIKEDSVSGKEARHSEEDTVYAFEINKNSPAAEETLETRERSQELAPLEKQSQRKKHRATRIQDKPVRKEDHNEGEDSELSLTQSDEGFCEIPNSLAPEVGKSSSEIAEPHVPEDSQSQIDHHGDAKQESHTNNPDPQKQGAPGESSREQEAVVLSIQ-EDGQLPEGQEQSARDGLHDGLSSRTKGGPGAAVEPSEGEEVQEATAGRENRKALEAESLEAQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBF6-1", "uniprot_id": "D3ZBF6_RAT", "id": "D3ZBF6-1", "name": "", "aln": "MSRLLRGIFCVIEIFHKYASEDGNKEAMLTHRELRQLLEGEIGDFLQPHVFHAVERKLNLLHFDRDGTISFEEFLLAIFSLLNPPYFDIS-LLNSEPRLMSKSEK--TDAVDLGAITGSTQRVVGVGPTQERLIFPPEMSLSDQSRKEEGEAGDELMVSPWEDVKTHGLPRNVSEPNDPEKHQPK--EDAQEIAQTVPAAEYDVVQYQRNTAVEVSKQSAGPT------QEIPRQGNKTSRRQSDTKISDYV-----------------IQRPTDYE------EHASATQDPILQKEDKVAGSAHTDLPVVAATGKSSQTQEVLEPTDDTRLSETQGTGKDAGRMPPETTHLEEPKADASASGSHSLPVQEREH------VQSRSRNVSETSSRGDLEEE-----------CKEHERKTRSLAPEAETPDEKCQEFPGSQRENDVERGTAALDPSSGEGNQNLPEVKEESISEKKARHSEKDTVDTFAINKTSPAIEETPETRERSQELAPLEEQSQGKQHRAAKTHDESVRKEDHSEGEDPELSPTQSDEGFCETPNSLAPEVGKSSSEIAETRVPGESQRQVEHHGDAKQESHINNPDSQKQGVPGESNREQEEVVLSIQ-EDGQLPEEQEE-------------------------EREE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5QJ38-1", "uniprot_id": "TCHL1_HUMAN", "id": "Q5QJ38-1", "name": "Trichohyalin-like protein 1", "aln": "MPQLLRNVLCVIETFHKYASED-SNGATLTGRELKQLIQGEFGDFFQPCVLHAVEKNSNLLNIDSNGIISFDEFVLAIFNLLNLCYLDIKSLLSSELRQVTKPEKEKLDDVDVQATTGDGQWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNRVDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQREDEPS-SQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQEPGKDADQTPAKTKNLGEPEDYGRTSETQEKECETKDLP-----VQYGSRNGSETSDMRDERKERRGPEAHGTAGQKERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVSGEEAEHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQPVEEEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQGDQHGESVQGGHNNNPDTQRQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARG--EHKNQGPGTKGPGAAVEPNGHPEAQESTAGDENRKSLEIEITGALDEDFTDQLSLMQLPGKGDSRNELKVQGPSSKEEKGRATEAQNTLLESLDEDNSASLKIQLETKEPVTSEEEDESPQELAGEGGDQKSPAKKEHNSSVPWSSLEKQMQRDQEPCSVERGAVYSSPLYQYLQEKILQQTNVTQEEHQKQVQIAQASGPELCSVSLTSEISDCSVFFNYSQASQPYTRGLPLDESPAGAQETPAPQALEDKQGHPQRERLVLQREASTTKQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:***.::**:* ***** ** .: * ** **:**::**:***:** *:****:: ***::* :* ***:**:****.*** *:**. **.** * ::*.** * **: * *. * .**..****: ::*. *: *.* **. . .: *.* .: ***.:* :.** ***:::: : *::**:** : ::* : * : *. : .*:::.** :**.:: .:.:*. * :** * . *** : : *: * *:* **:.*: : * ::**. **: ..****: :. * :: ::* .****.: *.:*. * **: . .: :: : :: ** *** ****. : . * **::* * . . :::* * * **: * :.:*.::.: : ** *:*. **:: ::* ::*.*:::.*. :* .*.:** *.* :***:*:*****:** :: *.:: :*:.*.:** :***.* . ****** .* *****.* *:**** .* * :** * ::**:: * .* ****.*:**.***..* * ** ::: ** **.* **: * ", "identical_positions": 244, "similar_positions": 193, "identity": "26.73%" }, { "cls_id": "homologset.agr.HGNC:31797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7V6-1", "uniprot_id": "SP202_HUMAN", "id": "P0C7V6-1", "name": "Transcription factor SPT20 homolog-like 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGK------------------------------------------------------------------------------------------TLQEKLYDIYVEECGKEP----EDPQELRSNVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQ---------------------------------------------------------REDGSFAETIRLPYEERALLDYLDAEELPPALGDVLDKASVN--------------IFHSGCVIVEVRDYRQSSNMQPP--------------------------------------------GYQSRHILLRPTMQTLAPEVKTMTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQRYSWPSVKPQQ--EQSDCPPPPELRVSTSGQKE-ERKVGQ-----------------------------------------------PCELNITKAGSCVDTWK--------------------------------------------------------------------------------GRPCDLAVPSEVDVEKLAKGY------------------------------------------------------------QSVTAADPQLPVWPAQEVEDP----------------------------------FRHAWEAGCQAWDTKP--NIMQSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHS-ACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSS---------------------------------------SGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEK---------------------------------------------------------------------------------------HPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG---------------GAAPSHSQKPS-------VPLIKASRRRPAAG-RPTRFVKIAP---------------------AIQVRTG------STGLKATNVEGPVR-----GAQVLGCSFKP-VQAPGSGAPAPAGIS-----------------------GSGLQSSGG-PLPDARPGAVQASSPAPLQFFLNTPEGLRPLT---LQVPQGWAVLTGPQQQSHQLVSL-----QQLQQPTAAHPPQPGPQGSTLG------------LSTQGQAFPAQQLLNVNLTGAGSGLQPQP------------------------------QAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPG--VQAGSQLVGQRKGGKPTPPAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AQ58-1", "uniprot_id": "A0A8I6AQ58_RAT", "id": "A0A8I6AQ58-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQHLAEALEQTDDIIETVQQEPPPANPVPSGEK------------------------------------------------------------------------------------------SLHEKLYDIYVEECEKEA----EVEG-LRSNVNLLEKLMRREALPCLVVNLYPENQGYSLMLK---------------------------------------------------------DKEGVLIEPFPVPYLGQKLLEYLDAEELPSFLIDVLEKSPVN--------------VFHHGCVIAEIRDYRQCSDIHPPRELGAEPAVSSDVSSAASSAETSAELSAESSAVASDVSSASSTPAYQTRHILLRPTMQSLVSDVESITSDNRQWTEEEKLELESQLILATAEPLCLDPSVAVACTANRLLFNQQKMMTDSMRQCFTSHEWPYLELEE--EQYICTTPPDVSTMVACRKQVETKQGD-----------------------------------------------QYDLKIAEAGKCVDTWK--------------------------------------------------------------------------------QRACEPEAPREVDVHKYARGK------------------------------------------------------------QMAPCDDAESTAWPLPEVND-----------------------------------YPFECEEGSQQWEPKPSTSTAQSLSDPFFSPEVRLPTEGRCDSQMYLPQVAPSDHSDDGSVAGERIEPGKAMGVGQESVQSTAECLGKILQGS---------------------------------------TDSIHLGQPSLGKKATSQS---VSSPAVETRIK---------------------------------------------------------------------------------------SPAPLLTQPSTSGQGSSAVSSSSISVRG-RKLPRLAPSPKSAGQAQQTFWGVSSVNTLPSAAQSSARS---------------TGSSPVIQGPSSGTGQNVINLLGLAQRAPVLMNSPSRVLSFPTGARASTETSSRGFLPPRSQMLSTQTRTPQRSVQTSVKLIVKNTSGPVTVRLPPGSVILHPELQAQRQQPWPQLQQPQQQP-----------------------WPQLQQPQQQPWPQPQQPQLQTWPQTQQPQQQPWPQPQQPQQQPWLQQPRPQQYVQPELQRQKQLEPLYVLIPKQHQPPRAPVPPRPVPPACPQR------------SNIQQWALSAQQSGLLNLAEAGR--VRQP------------------------------QATVVCQLGSTQQS-HGHNLPSQSFQYP-AARVQQLQARGQNVQLRFMPRRVAMP-------RAAIQQTHQG--HTGG-QYRGTGRGEPPTAPDS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU86-1", "uniprot_id": "SPT20_DROME", "id": "Q9VU86-1", "name": "SAGA complex subunit Spt20", "aln": "MQSLDSSCQEADFIINDTLKKLKGSSNADHVQGLAVHAHGSGVHQTQFVQYGTSGSSPQLQPQQSYHQLHPTLQQQQFASSSSKSYLETSLLQAIPQIPAQPPICIFDDDESPTEGTGGSLGSLLTEPTSATPSGLPTAIAPSPSSCSSSTTTMSNFNSITSPSPVVPDLLLSTPPGVNSSLSNSSTGAASVSSKKSEKRPPSANSTASGGGHHLHHHHLHQTHNHHVLASPTSSPSKRQKSNSSSKESSSSSRSSAIPAASVSTATSSSQSARAGAGAASSNSNSKPPSSVCQSGNSKFFNLHEKIRDLYLQLLSNDLNYFAETGLKQRTRSFTLERLVDREKLNTIVVNLYPGNKGYSLALHYDEHMVLNPQTNEWSPTDKDETSSDAAGLGTGTGSHRSRPKPLAQDESQSKTEAGHAKHDFGLVEVLRWPYENDLLLQCIDREMLPEFLMDLLVAETVSLSDGEGTRVYAKPSVFYAGCVIAQIRDFRQTFATSTN--------------------------------------------ICDMKHILLRPTNATLFAEVQQMG---SQLPAEDKLALESQLVLATAEPLCLEPDPSIGRQAINSQHQRQLYNSHELRRQMKKFTQTAINRKRKLDQFTHHHGLELCDYLARLRQRPRTGSSSGGANATPATAPTNNPLVGAMLSSFTSKVPRRPHEVIRPIRPPTLEYPANLKVPEHVISVEKYAKAYEPLNEFSEACKDGCQPNCRHNFQPQLVEEYILETEREASEGRRALYHIKLSIFQRPSDAEYLGELYVDRDYREGERNGESCRFALGTRVHANRYIQQFREIFTEEGRKAVKITHLIPGHMPIVTHTGLTNEQRILLQQQQQQQQRQAQMQQQQQQQQQQVVVVANQQQQSQQQQQTQQAGQQLSATVHHVALPRQQITQKTLNLAGSNVINVQQNFRQQSAQQQQPQTYTIEAPQQQAAAQIVPQQQQQQQQQQQQHIHLQQLATGSSNTSTTTHQVSLSNGSLVLVQQQQPQQQSQQLAQALQHSGITIQPATIQQQQQQVKGTSVVGANSALRAQLNSNVPILQTQLKVQQQQIMQKQQQQQTTATSNNNNNNNNNNNMNNNTAIHPNPAINAIVNSIMNSANQYQQQQQQQHQQQHQQQTGNTSSNNNAAGSGGSTNNNGSSTSATTLKNSSNASILNLLNSAPAAMTSTPVASGTFTTSTGQQQPQTLTLVQHQQQSTPNTADAATATYVQTTRGTPTLVSTQRKQQSSEVLQNLLNANRKIGGGGTTTTTFRTNSAGNLIAVNLNQAGQSHHQQTGDGSQTVRVSMSALASQLASPPAVMTNPTTSYTVISSGNS---AAAAAAWIQSPTGPVQQRILSSLRRDSTTAPPNAIVVGMAAPSPGSDSNASNASGFAVPNNLASTSSGGGGGGGALSALLTNAATPSPSGSDHSQSSQTHQNQALLERLSNVTSNVSAVSMPHMSPQQPQPTQQFITKTIVHSPATSSIHSPMSSPHPQPSASPQQQQQQQQQQTTATLNLQGINLSQLQGAMANFAGLQNVQVQIPGFTQPISLQFSGNSLQQQQSGNTATGAGTAQGQQRSVLVSVPVSSQQQQLPHTITLQTQSAPHHQQQHQQTQQQHAPPTGTIVSLPSSGPGTQTVVITNNSGGGVTAGSSTSGSAGGGGGSGATTAMLTLPIAQIVGAGVQKLNPQTIRTSNVGGGIGIAQQTVQQQTIQSQSGGNSTAAIQLLGTIQPRARNVQVVGTKQLANRQLITTQRQIGGSTLKIATTPVNAANVVTSSANLTTTPIVMSAQKLQLKTVKAPVQQQQQPQQQQQQLQQQHRILNQQSTATVSSQTLPSPNQVQVAQQQQQQQQQLQHIQIAGRATTASGAISQRTLTALAAAKQQQQQQQAAVNRRRSTTDATK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :: : .: . .:. * . . .*:**: *:*:: :: * *:. **:*: ** * ::***** *:***: *: .: : * : ** **: :* * ** * *:* .*. :*: ****.::**:** . : :******* :* .:*: : : . *:*: *****:*********:*. ::. * . .::* :. :.: : . . :: :. :* :: : :: . .. :*::.: .*:.: ..* .*...: : * . : : :.:: . : . * . . *. . : : : : : ..: * ... . . * : *:. *. : .: : * : * . :. . . ... . : *.. * :** ::. . .. : :.. . : .. :* :: . .:.. .. : * .: :: : .. : :. . *** . . * . .. . . : : : . .: : . . .*:* * ... . * :. * *:: * *. . * *. . : :** . . * * : : * . : . : : * .* . * * : . . ", "identical_positions": 118, "similar_positions": 236, "identity": "6.14%" }, { "cls_id": "homologset.agr.HGNC:318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8MR45-1", "uniprot_id": "ASPG1_DROME", "id": "Q8MR45-1", "name": "Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase CG1827", "aln": "MRRHLRASLWILCLATMAFSILAAVNTSPKPTLTSAFSGKAGTTAVKANKTTGELLPMVINTWNFTAANVLAWRILKQSKGGLRQTRNAVVEGCSKCEKLQCDRTVGYGGSPDELGETTLDAMVMDGATMDVGAVAGLRRIKDAIKVARHVLEHTQHTMLVGDAASAFANAMGFESESLVTPESKDMWLQWTAENCQPNFWKNVHPDPKVSCGPYKPRPTPLTRWK-EDRARNEYEIGRKNHDTIGMIAIDVESNIHAGTSTNGARHKIPGRVGDSPIPGAGAYADNEVGAAVATGDGDVMMRFLPSLLAVETMRAGKPPAEAAQEGLRRILKHHKDFMGALIAVDRLGNYGAACYG------LAEFPFMVSSPAGADGPTRLETVKCIGGQDKVN-----IVAL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBI7-1", "uniprot_id": "A1ZBI7_DROME", "id": "A1ZBI7-1", "name": "", "aln": "---------------------------------------------------------MVINTWPFAEAKKEAWRLLNVKKGGLGQTRSAVVGGISMCEKLQCAKTVGYGGNPDERGDTSLDALLMDGGTMEVGAVGDLRRIRSAIKVAQHVLEHTLHTLLVGDGADEFANAMGLQYESLNSEDNIESLKNWTRHNCQPNFWRNVHPDPRTSCGPYQP----LVTWDPNAKQSDRIEIGPDNHDTITMAAIDEEGHIHVGTSTNGLRYTLPGRVGDASIPGSAAYADNEVGAAVTTGDGDILMRFLPSLLAVEAMRAGKTPAEAVELVIQRIQKHVKYFEVAVIVANRLGTYAVRCHGTGMARDNGKFAYMVSSPG---QPVRTESVECSANPEKSPSEDDRQVIW---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30919-1", "uniprot_id": "ASPG_RAT", "id": "P30919-1", "name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "aln": "---MARKWNLPFLLLPLVLGIPLVRGSNP--------------------------LPLVVNTWPFKNATEAAWWTLVS--GGS--ALDAVEKGCAMCEKEQCGGTVGFGGSPDEVGETTLDAMIMDGTAMDVGAVGGLRRIKNAIGVARKVLEHTTHTLLVGDSATKFAVSMGFTSEDLSTNTSRALHSDWLSRNCQPNYWRNVIPDPSKYCGPYKP-----PDFLEQNNRAHK-EVDIHSHDTIGMVVIHKTGHTAAGTSTNGLKFKIPGRVGDSPIPGAGAYADDMAGAAAATGDGDTLLRFLPSYQAVEYMRGGDDPARACQKVISRIQKYYPKFFGAVICANVTGSYGAACNRLP---TFTQFSFMVYNSL--HNQAIEEKVDCM-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64191-1", "uniprot_id": "ASPG_MOUSE", "id": "Q64191-1", "name": "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "aln": "---MERKSNLSLLLLLLVLGMPLVRGSSP--------------------------LPLVVNTWPFKNATEAAWWTLLS--GGS--ALDAVENGCAVCEKEQCDGTVGFGGSPDEGGETTLDAMIMDGTAMDVGAVGGLRRIKNAIGVARRVLEHTTHTLLVGDSATKFAESMGFTNEDLSTKTSRDLHSDWLSRNCQPNYWRNVIPDPSKYCGPYKP-----SGFLKQSISPHKEEVDIHSHDTIGMVVIHKTGHTAAGTSTNGIKFKIPGRVGDSPIPGAGAYADDTAGAAAATGDGDTLLRFLPSYQAVEYMRGGDDPAIACQKVILRIQKYYPNFFGAVICASVNGSYGAACNKLP---TFTQFSFMVSNSL--HNEPTEKKVDCI-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20933-1", "uniprot_id": "ASPG_HUMAN", "id": "P20933-1", "name": "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "aln": "---MARKSNLPVLLVPFLLCQALVRCSSP--------------------------LPLVVNTWPFKNATEAAWRALAS--GGS--ALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKP-----PGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLS---TFTQFSFMVYNSE--KNQPTEEKVDCI-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2C3-1", "uniprot_id": "ASPG2_DROME", "id": "Q9W2C3-1", "name": "L-asparaginase-like protein CG4372", "aln": "--MLAQSCCLRLLILLLLFTTIGSVPKKSLKYFTNRKLRERRIKLFG--TKKTEIQSLLISTWNYTDANLQAWSVLQQ---GPRRTRQAVIQGCMACQNQRCGRLLTGRSSPDTEGALTLEAAIMDGESLEYGAVAGMNGVRNAILVADAVLKYTKHSVLVGKSATKFARSLGYKEEYLTDARTRNVLKKWRSNGCQPNFWRDVHPSPAENCGPYSP----LPEHMHQHPMHQEYAIIQGQHDQLAFLALDAEGKFHVASQSSGAQFRIPGRVGDSAVPGAGIYADNEVGGAVASGDGDVLMRHLPAFLAVEAMRAGKEPDKAAELVVQRLLRHNTEFNGAVVVVNRRGIYAAACAG------LDEFHFVVSGGKEYLSMARVERVKCLERENEVIDGGPKGLFPTIPEKHKVP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::.** : *. ** * * : .** * *:. :* : ..** * :*:* :*** ::: ***..:. ::.** ** **::* *::***..* ** ::* * * . .* ..****:*::* *.* ****.* : .. ** : : .:. .: ..:.:.* :. : *****:.:**:. ***: .*.*.::*:** ::*.**: *** ** *. * * : : *: :: * *:: .. * *.. * :* ::* . : *.* ", "identical_positions": 93, "similar_positions": 97, "identity": "22.46%" }, { "cls_id": "homologset.agr.HGNC:3180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21451-1", "uniprot_id": "EDNRB_RAT", "id": "P21451-1", "name": "Endothelin receptor type B", "aln": "MQSSASRCGRALVALLLACGLLGVWGEKRGFPPAQATPSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRVAGVPPR--SF-PPPCQRKIEINKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINAYK-----------------LLAGDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDVITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAIFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPQRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48302-1", "uniprot_id": "EDNRB_MOUSE", "id": "P48302-1", "name": "Endothelin receptor type B", "aln": "MQSPASRCGRALVALLLACGFLGVWGEKRGFPPAQATLSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRGAGVPPR--SF-PPPCQRNIEISKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYK-----------------LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDMITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAVFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPHRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24530-1", "uniprot_id": "EDNRB_HUMAN", "id": "P24530-1", "name": "Endothelin receptor type B", "aln": "MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATP-LLQTAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPR--TISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK-----------------LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TTH1-1", "uniprot_id": "A0AB32TTH1_DANRE", "id": "A0AB32TTH1-1", "name": "Endothelin receptor type B", "aln": "MRFQIIMETRCVFCFLFL---------------------LTEHIAVMSAQGKDFNQSRLSMGPLSPTQKSTIVIGNQINESMPRRPKVLPPMCTDPTEIRDTFKYINTVVSCLVFVVGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIMIDIPINVYKITVLKSETQFFTDMIVPLLAKDWPFGVGLCKLVPFIQKTSVGITILSLCALSIDRFRAVSSWNRIKGIGVPKWTAIEIILIWVLSIILAVPEAIAFDMITMDYKGEQLRICLLHPKQRIKFMQFYKKAKDWWLFSFYFCMPLTCTAIFYTLMTCEMLRKKNGVQIALSDHIKQRREVAKTVFCLVLVFALCWLPLHLSRILQRTIYDERDPNRCELLSFFLVLDYIGINMASVNSCINPIALYMVSKRFKSCFRSCLCCWCLPP-EILAMDDKQSCIKLKEELQQVVHLWNTHIIRRSRSAVAPSGRPILMYTIPHLFGGQDYLKEVSQNSVDVCKQECQQRGPYTCDETVFSLCCLIMSENFLTPPSTADESIELYLFLRAYILKDLQLGHFY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *.:..::: * :*:. * . . . : : *.: ** .. ** * ** .*******:*******:*************************************:******.** *** *****. :*********:*****:**********:***:**.************:**:****:*::*******.**:** ****. **:*:*:* *: ******.************:**: **.*************.*:****.**:******************************: *:*:: :*:*******:************:**********:******.**:******* . * ::::****:*:* : : :: .:: * ", "identical_positions": 276, "similar_positions": 77, "identity": "49.46%" }, { "cls_id": "homologset.agr.HGNC:31802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96CB9-1", "uniprot_id": "NSUN4_HUMAN", "id": "Q96CB9-1", "name": "5-cytosine rRNA methyltransferase NSUN4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAALTLRGVRELLKRVDLATVPR-----------RHRYKKKWAATEPKFP--------AVRLALQNFDMTYSVQFGDLWPSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAK----------------------------------DFVNEAISHWELQSEGGQSAAPSP-ASWACSPNLR---CFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQP----------------GDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEE----------------------------------------------------NNIFKRSRKKERQILPVLQVQLLAAGLLATKPGG-------------------------------------------------------------HVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMD----TFCFFS--SCQVGELVIPNLMANFGPMYFCKMRRLT------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A099-1", "uniprot_id": "D4A099_RAT", "id": "D4A099-1", "name": "5-cytosine rRNA methyltransferase NSUN4", "aln": "-----------------------------------------------------------------------------------------------MELNLYRADGTVIILTHGNVNEFCPGKMDLCQVWHG--------LGRDRMMVPAPRSIQASSSSQFSPEPARVQLLFQSELLALLADMAAPVLRGVRKLLKLADFTPVPR-----------RHRYKKKWATTEPQFT--------PSRLALQNFDMTYSVQFGDLWPSIRVSLLSEQKYGALVNNFAAWDSVSAKLEQLSAK----------------------------------DFVSEAISYQKLEPESGLSPTLS----LDCSPNLR---CFTFSKGDVSRFPPASVGSLGLMDYYLMDAASLLPVLALGLQH----------------GDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSTSRTGRLQKVLHSYVPQDIRKGNHIRVTSWDGRKWGELEGDTYDKVLVDVPCTTDRHSLHEDE----------------------------------------------------NNIFQRSRKKERQMLPMLQVQLLGAGLLATKPGG-------------------------------------------------------------HVVYSTCSLSHLQNEYVVQGAIELLANQYNIKVQVEDLSHFRKLFMD----TFCFLP--SCQVGELVIPNLMANFGPMYFCKLHRVP------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPX3-1", "uniprot_id": "Q9VPX3_DROME", "id": "Q9VPX3-1", "name": "NOL1/NOP2/Sun domain family member 4", "aln": "-----------------------------------------------------------------------------------MLKARNVCLLSRRWKSGAKKRWNVLQNKKNNCDRALENFDDFYGSVYG--------TRWKNMRAALLTRHKYVALVNNFGDTEQTCAMLESDGAINMKSLINLAQDRVKDSTETVPEQGKSRHEIESKLDALLRKQQEREVASIYPSSPEDGSSAPLPLELKFDNVEEDQPEQVNNPFKQSLTKALEEDVKLDEHRLVDPQFGTGGLYEYMPAHSIKGME----------------------------DWVAESEHYKYYQTSADFPLAIEPEPSFHYPEHLS---LYTYEMGNCSDFKGPKKCMTGVLSHFMMDGASTLPPLFLQVKP----------------GERVLDACASPGGKSLLMLQTLHLDHLVCNDIQESRLNKLRKVMQEYLFDYKERWAGKRLILSQSDARNLDQYEQFDKILVDVPCTTDRHVLNEQD----------------------------------------------------NNIFKPTRIKERLRIPELQAGILANCLRLLRPGG-------------------------------------------------------------SLVYSTCSLSPIQNDGVVHMALQKVFTEYGITTTIKDLSRHTALFSD----VFKFEHPKGLKYGQMVVPYLPANFGPMYFSKITRNV------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C4P6S0-1", "uniprot_id": "SHTAP_MOUSE", "id": "C4P6S0-1", "name": "Sperm head and tail associated protein", "aln": "MNSSPPFLLKISAPSTSPQADCPNNYSFPPESPSSCRKGFTPVLTLEVPVAPGKDFNDHLSCNAGLSPNAGNRFTNPPYSREPFSCLTISSPCLPRRIPTPPPPPPVLSSPPPPERCPFEPFSPLLGRLYRQEPAGSSSPCFDRFSLQGSPSPHQRNLCCNYIDSPESQRSCPPSPRLCYVTSPPLIHQAPRASPVTSPELTHITLETGPVISTPLMPGSQGNYSIISPLLTHRPLRPGLAISPPLAHRSVETRPLTPASISHRGPHCPSRRSYNDPPLSSASSPPSGNPYHDNPMPPNSCEPKPQLDVPLGKNGCGPPLSSQAGMSGSPISPQEGCIHYSHLCPDSQISAPRSPFCVINLPPESAGSPSSSLPQALQKPCVGSFLWEPGGNSYLLLTPGTIISGPSCTTGPPLPQCPNPSPYFPSPLNNQCVAPPQSPRGYNEPRPPTSAPPQMKSPKSPESRRNPYKCRSLDNTPHHTPPSHSKSHKTNTCPQPPSQSFGLFSPCMEPAITTTSNSCPKEPPPETAVLKTVAPTSCPHSSPCNPALPSRYPKSSPHVPPPVSPCNTHMYSVVPPTSHLSPLSSPLNQSIPLPQPAVLPCGTYSAPRGPPSHIKSVAPPCSTHIYSFIPLRTPFDPRCLPVVPRARFCPTTVPCGIHTYAVTSPVPLNNPSQIPYSCSLPPSKTSSTCSTSVSSTIVCSDYQSSDSQINHQNKSQSPNKNSSLHNQSKSPLRRGAFQSRSRSRSSSPLQSSTQDRNESTNMGVKHHKRSRKQSQSPADGKIESQSKSLQHRKSVGQIKSPHSKKK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : * . . : : . .. . . . . . . : ... . . . . . : . . . * .: :: .: :. .: : :* * . * :: . . ** : . . . :. : . **.. :* .. :. . :* * :* * : :***. :.. . ::. . .::.: : : * : . .*: .. * ", "identical_positions": 20, "similar_positions": 89, "identity": "2.48%" }, { "cls_id": "homologset.agr.HGNC:31810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJS1-1", "uniprot_id": "A0ABK0LJS1_RAT", "id": "A0ABK0LJS1-1", "name": "", "aln": "MSSQGSYAKVAESFENISEHSCLSETSGALVDTETISDIKMKGPEVSLAPSSNVTETEESSVSSPQNTDENSGDGYQGYEGDDDDDDDD-------SNLPSFEDSDNFISSTECSSSPQELEEGEIVEEQSVGRLFHHYELEAGEVVEAQGVQNLFCSYELEEGEVLEAPRVQSMLCHYELEAGEVVEAQEVQGLFCHYELEEGEVVEAQGVQSLVQYHELEEGEVVEAQGVQSLVQYCELEEGEVVVAQGVQSLVQHHELEEGEVVEHEIGSLLLRRHHVLDACEIVEEQGLESPFHHRVLGQGVVGNDQDEVSEVYEQNSVERSEQYDIED-SSIDEWMALETSPLLKPRWNVLNALRDRQ-LGSSGRFVYEACGARLFVQRFSLEYVFEGHAGCVNTVHFNQRGTLLASGSDDLKVIVWDWLHQRPLLNFDSGHKNNVLQAKFLPNCNDAILAMCGRDGQVRVAHLSAMAGTHMTKRLVKHGGASHRLGLEPDSPFRFLSSGEDAVVFSIDLRQAQPASKLMVTKDGDK----KVGLYTVFVNPANVYQFAVGGQDQFVRIYDQRKIDENVNNGVLKKFCPHHLISCEYPAYITSLMYSYDGTEVLASYNDEDIYIFNSSDSDGAQYAKRYKGHRNNATVKGVYFYGPRSEFVMSGSDCGHIFIWEKSSCQIVQFLEADEGGTINCIDPHPYMPVLASSGLDHEVKIWSPIAETSSKLTGLKNVIKINKLKRDNFTLHHTSLFDNHMLWFLMSHLTQSNYQRNLRGIRIEVGGG---DFSDS---------------SSSSDEEENQD-SQCQTS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AHY8-1", "uniprot_id": "A2AHY8_MOUSE", "id": "A2AHY8-1", "name": "", "aln": "MSSHESYTNAAETPENISILSCLGETSGALVDTKTISDIKTMDPEVSLTPSSDVTGTEDSSVLSPQSTDVNSVDSYQGYEGDDDDEEDDEDDKDGDSNLPSLEDSDNFISCLENSYIPQNVEKREVVEEQSLGRRFHPYELEAGEVVEGQGGGSLFYPYELEAGEVVEAQNVQNLFHRYELEEGEVVEAQVVQSMFPYYELEAGEVVEAEEVQGFFQRYELEAREVIGAQGGQGLSRHYGLEGGEVVEATAVRRLIQHHELEEGEDVD-----------------------------------------DQEESSEMHEETSEDSSEQYDIEDDSLIDEWIALETSPLPRPRWNVLSALRDRQ-LGSSGRFVYEACGARLFVQRFSLEHVFEGHSGCVNTVHFNQHGTLLASGSDDLKVIVWDWLKKRSVLNFDSGHKNNILQAKFLPNCNDAILAMCGRDGQVRVAQLSAVAGTHMTKRLVKHGGASHRLGLEPDSPFRFLTSGEDAVVFNIDLRQAHPASKLLVIKDGDK----KVGLYTVFVNPANVYQFAVGGQDQFMRIYDQRKIDENVNNGVLKKFCPHHLLSSDYPAHITSLMYSYDGTEILASYNDEDIYIFNSSDSDGAQYAKRYKGHRNNSTVKGVYFYGPRSEFVMSGSDCGHIFIWEKSSCQIVQFLEADEGGTINCIDSHPYLPVLASSGLDHEVKIWSPIAEPSKKLAGLKNVIKINKLKRDNFTLRHTSLFNNSMLCFLMSHVTQSNYGRSWRGIRINAGGG---DFSDS---------------SSSS-EETNQE-S--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGE4-1", "uniprot_id": "DC8L1_HUMAN", "id": "A6NGE4-1", "name": "DDB1- and CUL4-associated factor 8-like protein 1", "aln": "MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGG---DTRDGGFLNDASTENQNTD-------------------------------------SESSS--------EDVELESMGEGLFGYPLVG-------------------------------------------------------------EETERE-----------EEEEEMEEEG------------------------------------------------------------------------------EEEEQPRMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQ-LGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDK----KVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSS---------------TSDTSEEEGQDRVQCIPS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W091-1", "uniprot_id": "Q9W091_DROME", "id": "Q9W091-1", "name": "DDB1- and CUL4-associated factor 8", "aln": "MDVEDSVASGAASACKRQKRNTDSQNDGEPEDAAQIGEENTVAESQPLINFDTIVTHNNNGESDMEGKENQLQDESE--------------------------------QSEEHLANKVGPEELPEIEQAGSSNLAHQLSPEAASTVLASDEPDASTGVIEPSDSEDYPPTSPTPIEASEAVSSPRFNPRNIPPTRSYRRISIELVGSYSDTSDSEEHELEEGTEHAEEYSDDAPEPHIAESADDSSSNDDMGPYSLSSEDETTTEVEN-------------------------------------LQDEVEFNEDINPADREKVDYAVNQVMCKCKPKYTWNYDQELLQREHNIINRIDWRGGHTSASSFGQGYYGSRQVVEQMTLLSSLNVHHGCVNSLNFNRAGDLICSGSDDLTIVVWDWAKEKQLHRFRSGHNMNIFQTKFIDSAGCLDIVSSSRDGQVRRSVIPPSGGVIKPIRLYTHSESVHKIIVVPHSRHELMSAGEDAAVKHFDLRASNAATTMMRCVYNDENERGRVRLFSIAHHPY-APEFCVSGSDDILRVYDKRNLAK-----AIHQMAPRNLLEAQI-TQITCAVYNHSGSEILASYSDAGIYLFDSRNYNRGDYLHCYKGHINSRTIKGVNFFGPRSEYIVSGSDCGNIFFWDKNTEAIINYMKGDHVGVVNCLEPHPWMPVLATSGLEHDVKIWTPQG-PERKLP--EDLLKQTLQRNFRCNIVESIDLDINNFQYFIRGFLQGSGASHLRQRHTSSLGHQMRDNSSSRSNGSNASNPTSHRRNSNSSDDTNDEGADADAALDTLHCRTQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . : . . . : .* : .: : . . . .:.. . ..: : * * :* . .. . . . . * * . : : : . :: . * : . :::. : * *:. * *:* .*::: * : * *.*.:::**: * :.*..*** ::**** ::: : .* ***. *::*:**: ... :. ..:***** : : . . *: .* . *.: : *.* ..::::****.* :*** ..*:.:: .*: :* *::: :* :*.*.* *:::*:**:*.: : .:::: *::*: .: : **. :*.:.*:*:****.* .**:*:* : .:* : **** *. *:* * *:*****:::******::*:*:*.: *:::::.*. . :**::.**::****:***::.*:**:* . . :*. ::::* . .. . .: : :: : ::: . * * . . * *.* .*.: :: .:: ", "identical_positions": 133, "similar_positions": 220, "identity": "16.08%" }, { "cls_id": "homologset.agr.HGNC:31811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJS1-1", "uniprot_id": "A0ABK0LJS1_RAT", "id": "A0ABK0LJS1-1", "name": "", "aln": "MSSQGSYAKVAESFENISEHSCLSETSGALVDTETISDIKMKGPEVSLAPSSNVTETEESSVSSPQNTDENSGDGYQGYEGDDDDDDDD-------SNLPSFEDSDN----FISSTECSSSPQELEEGEIVEEQSVGRLFHHYELEAGEVVEAQGVQNLFCSYELEEGEVLEAPRVQSMLCHYELEAGEVVEAQEVQGLFCHYELEEGEVVEAQGVQSLVQYHELEEGEVVEAQGVQSLVQYCELEEGEVVVAQGVQSLVQHHELEEGEVVEHEIGSLLLRRHHVLDACEIVEEQGLESPFHHRVLGQGVVGNDQDEVSEVYEQNSVERSEQYDIED-SSIDEWMALETSPLLKPRWNVLNALRDRQ-LGSSGRFVYEACGARLFVQRFSLEYVFEGHAGCVNTVHFNQRGTLLASGSDDLKVIVWDWLHQRPLLNFDSGHKNNVLQAKFLPNCNDAILAMCGRDGQVRVAHLSAMAGTHMTKRLVKHGGASHRLGLEPDSPFRFLSSGEDAVVFSIDLRQAQPASKLMVTKDGDK----KVGLYTVFVNPANVYQFAVGGQDQFVRIYDQRKIDENVNNGVLKKFCPHHLISCEYPAYITSLMYSYDGTEVLASYNDEDIYIFNSSDSDGAQYAKRYKGHRNNATVKGVYFYGPRSEFVMSGSDCGHIFIWEKSSCQIVQFLEADEGGTINCIDPHPYMPVLASSGLDHEVKIWSPIAETSSKLTGLKNVIKINKLKRDNFTLHHTSL--FDNHMLWFLMSHLTQSNYQRNLRG--IRIEVGGGDFSDSS-----------SSSDEEENQD-SQCQTS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AHY8-1", "uniprot_id": "A2AHY8_MOUSE", "id": "A2AHY8-1", "name": "", "aln": "MSSHESYTNAAETPENISILSCLGETSGALVDTKTISDIKTMDPEVSLTPSSDVTGTEDSSVLSPQSTDVNSVDSYQGYEGDDDDEEDDEDDKDGDSNLPSLEDSDN----FISCLENSYIPQNVEKREVVEEQSLGRRFHPYELEAGEVVEGQGGGSLFYPYELEAGEVVEAQNVQNLFHRYELEEGEVVEAQVVQSMFPYYELEAGEVVEAEEVQGFFQRYELEAREVIGAQGGQGLSRHYGLEGGEVVEATAVRRLIQHHELEEGEDVD-----------------------------------------DQEESSEMHEETSEDSSEQYDIEDDSLIDEWIALETSPLPRPRWNVLSALRDRQ-LGSSGRFVYEACGARLFVQRFSLEHVFEGHSGCVNTVHFNQHGTLLASGSDDLKVIVWDWLKKRSVLNFDSGHKNNILQAKFLPNCNDAILAMCGRDGQVRVAQLSAVAGTHMTKRLVKHGGASHRLGLEPDSPFRFLTSGEDAVVFNIDLRQAHPASKLLVIKDGDK----KVGLYTVFVNPANVYQFAVGGQDQFMRIYDQRKIDENVNNGVLKKFCPHHLLSSDYPAHITSLMYSYDGTEILASYNDEDIYIFNSSDSDGAQYAKRYKGHRNNSTVKGVYFYGPRSEFVMSGSDCGHIFIWEKSSCQIVQFLEADEGGTINCIDSHPYLPVLASSGLDHEVKIWSPIAEPSKKLAGLKNVIKINKLKRDNFTLRHTSL--FNNSMLCFLMSHVTQSNYGRSWRG--IRINAGGGDFSDSS-----------SSS-EETNQE-S--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7V8-1", "uniprot_id": "DC8L2_HUMAN", "id": "P0C7V8-1", "name": "DDB1- and CUL4-associated factor 8-like protein 2", "aln": "MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENRS--------SDQESASED-------IELESLEDFEH----FLMSGES---------------------LFHYPLVGEEETER----------EEEDEEIQE---------------------------------EGGEEEEEEEEE----------------------------------------------EEEEEEEEE-----------------------------------------EEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSALPRPRWQVVTALHQRQ-LGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDK----KVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCDFPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGPRSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIWTPTAKAATELTGLKKVIKKNKWERDEDSLHHGSL--FDQYMLWFLLRHVTQRGRHQDWRSGEAEFPDEESDESSST-----------SETSEEEVQDRVQCMPS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W091-1", "uniprot_id": "Q9W091_DROME", "id": "Q9W091-1", "name": "DDB1- and CUL4-associated factor 8", "aln": "MDVEDSVASGAASACKRQKRNTDSQNDGEPEDAAQIGEENTVAESQPLINFDTIVTHNNNGESDMEGKENQLQ-------DESEQSEEHLANKVGPEELPEIEQAGSSNLAHQLSPEAASTVLASDEPDASTGVIEPSDSEDYPPTSPTPIEASEAVSSPRFNPRNIPPTRSYRRISIELVGSYSDTSDSEE----------HELEEGTEHAEEYSDDAPEPHIAESADDSSSNDDMG-------------------PYSLSSEDETTTEVEN-------------------------------------LQDEVEFNEDINPADREKVDYAVNQVMCKCKPKYTWNYDQELLQREHNIINRIDWRGGHTSASSFGQGYYGSRQVVEQMTLLSSLNVHHGCVNSLNFNRAGDLICSGSDDLTIVVWDWAKEKQLHRFRSGHNMNIFQTKFIDSAGCLDIVSSSRDGQVRRSVIPPSGGVIKPIRLYTHSESVHKIIVVPHSRHELMSAGEDAAVKHFDLRASNAATTMMRCVYNDENERGRVRLFSIAHHPY-APEFCVSGSDDILRVYDKRNLAK-----AIHQMAPRNLLEAQI-TQITCAVYNHSGSEILASYSDAGIYLFDSRNYNRGDYLHCYKGHINSRTIKGVNFFGPRSEYIVSGSDCGNIFFWDKNTEAIINYMKGDHVGVVNCLEPHPWMPVLATSGLEHDVKIWTPQGPERKLPEDLLKQTLQRNFRCNIVESIDLDINNFQYFIRGFLQGSGASHLRQRHTSSLGHQMRDNSSSRSNGSNASNPTSHRRNSNSSDDTNDEGADADAALDTLHCRTQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . :. . . . : .* : .: . . .: . .:.. . ..: . .:.:. .:. :* .:*: . . * * . * : . * * : : * * : : : . . :: . * : . :::. : * * * *:* .*::: * : * ****:::**: * :.*..***.::**** ::: : .* ***. *::*:**: ... :. ..****** : : . . : * . *:: : *.* ..::::****.* :*** ..*:.:: .*: :* *::: :* . :*.*.*.*:::*:**:*:: : .:::: *::*:..: : **. :*.:.*:*:****.* .**:*:* . : .:* : :*** *. *:*** *:*****:::******:**:*:*.: *:::::... *.:**::.**::**** ***:*:****:* . . .* : .: . : . .: *: : ** :. : . .: .. *..: *.: :: :: ", "identical_positions": 140, "similar_positions": 227, "identity": "16.91%" }, { "cls_id": "homologset.agr.HGNC:31813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AB59-1", "uniprot_id": "RHG27_MOUSE", "id": "A2AB59-1", "name": "Rho GTPase-activating protein 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEG----DVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQR--PAVPEP-LAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTGGQRNSLAPG------------------------------------------------GPACLYVRPAAPVRPAQSLDDLARGGTAPP----------------AGLLGSAGHFKASSVAGSWVCPRPLAPSDSE-NVYEAIPDLRCPPRAESPKQVDDPPE--------------------PVYANVERQPRATSPRSAAAP------------------PRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFET--------PEGTTSP------ATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEEL---EEDHQEQLE--MQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASP--LVAPPGWSCQITPDKQMLYTNQFTQEQ--------------------------------------------------------------------WVRLEDQHGKPYFYNPEDSSVQWELPQVPIP------------------------------------APRSVRKSSQDSDTPAQASP-----------PEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPK------DKSSKKNVLELRSRDGSE--------------------------------------------------------------YLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWRE-------------EDVRQNAASPSLSPGGLESDLSRVRHKLRKF----LQRRP-----TLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEAR--GLDIDGLYRISGN-LATIQKLRYKVDHDER-----LDLDD--GRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS---------------------RCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TLK4-1", "uniprot_id": "RHG27_RAT", "id": "Q6TLK4-1", "name": "Rho GTPase-activating protein 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEG----DVYVLVEHPFEYTGKDGRLIAIQPNERCRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPVPAPQPSVLQQR--PTVPEP-LAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTSGQRNSLAPG------------------------------------------------GPACLYLRPAAPVRPAQSLDDLARGGTAPP----------------AGLLGSAGHFKASSVAGSWVCPRPLARSDSE-NVYEAIPDLRCPPRAKSPKQVDEPPE--------------------PVYANVERQPQVTSPRSAAAP------------------PRLSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA--------PEGATSP------TTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEEL---EDDPEEQLE--MQPSLSPRSPGQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSP--LVAPPGWSCQITPEKQMLYTNQFTQEQ--------------------------------------------------------------------WVRLEDQEGKPYFYNPEDSSVQWELPQVPVP------------------------------------APRSGRKSSQDSDTPAQASP-----------PEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWNASWTVLEGGVLTFFKDSKTSAASGLRQPSKLSTPEYTVELRGASLSWAPK------DKSSKKNVLELRSRDGSE--------------------------------------------------------------YLIQHDSEAIISTWHKAIAEGIEELSADLPQREEGEPSSADFGSSERLGSWKE-------------EDVRPNAASPSLNPGSQESDLSRVRHKLRKF----LQRRP-----TLQSLREKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEAR--GLDIDGLYRISGN-LATIQKLRYKVDHDER-----LDLDD--GRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS---------------------RCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZUM4-1", "uniprot_id": "RHG27_HUMAN", "id": "Q6ZUM4-1", "name": "Rho GTPase-activating protein 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVVG----DVYVLVEHPFEYTGKDGRRVAIRPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGNPAAAAPP-GPHPS--PAAPEP-LAYDYRFVSAAATAGPDGAPEESGGRASSLCGP-------------------AQRGAATQRSSLAPG------------------------------------------------LPACLYLRPAAPVRPAQSLNDLACAAVSPP----------------AGLLGSSGSFKACSVAGSWVCPRPLARSDSE-NVYEVIQDLHVPPPEESAEQVDDPPE--------------------PVYANIERQPRATSP-GAAAA------------------PLPSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA--------AEGAASP------ATSPASVDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAEN------EPEEELE--MQPGLSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSP--LTTPPGWSCHVSQDKQMLYTNHFTQEQ--------------------------------------------------------------------WVRLEDPHGKPYFYNPEDSSVRWELPQVPVP------------------------------------APRSIHKSSQDGDTPAQASP-----------PEEK-VPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFSTPEYTVELRGATLSWAPK------DKSSRKNVLELRSRDGSE--------------------------------------------------------------YLIQHDSEAIISTWHKAIAQGIQELSAELPP-EESESSRVDFGSSERLGSWQEK-----------EEDARPNAAAPALGPVGLESDLSKVRHKLRKF----LQRRP-----TLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEAR--GLDIDGLYRISGN-LATIQKLRYKVDHDER-----LDLDD--GRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRS---------------------RCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIFPPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2D3-1", "uniprot_id": "A0A8M2B2D3_DANRE", "id": "A0A8M2B2D3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPDPLFAPQHVWATMSLSQQVLVNYEYTYTARDGRNVSIKPNEHYILVNKTNEEWWHVQKDAADKPFYIPAKYVTELPPETSQTPLDPPEEFSG--YESLQFGSQTADPAEVTLRVPDSIKRDTEKDGHRISTFIIPKEFFELKGLDPDPIKTEAEAGPPVSSNTSSPTNG-----------------------------------------------ETAFIILPPPVYTVNTTQSTETDTRSVDDP------------KDSVGRPRVDSSTIDEDIQMLNRAGWSEVLDVMGKEKNVYESLDTVREPES---PKDEADMTVNTTPVTPDAPMVEDD----TAVYVNIPRKRQTTINNSSPIASLLQD-----FPEPPENFLLDSAGWQVHTDDQSGQEFYYQPSTGRSTWENPLSSRSMESPVGTEGGRSPPSFPQSPACSPVAPAPRRWSSDWEKVLDESTGRHYFFNTVSGQSSWDPPE------DVDSPGRLM--FLDDCPPPLPEEDYPASPELEEASPVSIPAEYSLIHVKKVSIPRVSLD--RSSPAGWSLDIDSEGTWTFTSEYTQEQ--------------------------------------------------------------------WIKSLDDQGRTYYYLRDGSKSQWNLPEINPGQGGVAAQWLALLPYSKNVAGSSPGWYSASPGQYGVGNGASGEQDTVGSNWRHSAGY-----------PDDKNHSSYIQNTSDSEASSSPDTPHNVSNLEKAGILNKTKVSENGKKVR-KNWGHSWTVLHGGKLTFHKDPKSTPAG-ASSKTNQILPEFTVDLKGATINRAPK------DKSSKKNVLELKTRTGAE--------------------------------------------------------------YLIQYDTDSIIQDWHKVILDTIHQLNGDQHHSEEEDEVIDKSPTLDREERPFE-------------KRTMSTATRQPSTSSTSEAEQKKVRTKLKKF----LLKRP-----TLQSVKDKGYIRENVFGCHLHNLCSQEKTRVPSFVEKCIRAVEKR--GLEIDGLYRVSGN-LAVIQKLRFKADHED------LDLEE--GNWD-IHVITGALKLFFRELQEPLFPYNLFNEFICAIKTPDYYSKI---------------------SHMRNLVRSLPPPNHDTMEALFSHLRRVIQHGNENRMTVQNVAIVFGPTLLKPEEETASIATYMVFQNQIVEFLLSEFESIFHM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B765-1", "uniprot_id": "A0ACD6B765_DANRE", "id": "A0ACD6B765-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGETGKMTSVHTLG------LVLVEFEYEYEGRDGHMVCIKPNERYILLAKTNDHWWHVCKDERAKPFYIPAKYVKELPPN-IPSPLDYREPPGPDVKPAVPDLTETRKADEVTIRLRS--KGNYHKTENRMSTFGVPLDLHEPPSYKHGGPSDSLISLSSVSASDSSKQKKRMSHAPNL----------------------------------LFGSHSNLPTELVPDKFRVPSFSPADPLHRPIPAKPVEIPIIK----NLNETKPHRTSPELESPIEPESESSSSEPMPSPDSE-NIYESISDLNIDLSSLTDKEPAGLPDTQTTTSSLPPSIKTDNDPTTALYANVADIKKNIPRSSNSSVSTCSSPGITLSPAPDSISPPSSAEWRVHTDHDSGKEFYYHPATGQSSWSDPRSP---QPGAGMESVTAP-----VPASSP--PSAR---SDWEQLLDEATGRHYYYNHASNKTSWTAPEPSAPASSKQGPHSQD--KDKERPPPLPEEDYPKNQHEESHISFQLPKDFQLPQIKRAVIPRAVMDTNKDVPTGWTQSVGTDGKSVFTSELTHEQ--------------------------------------------------------------------WIQSKDEKGKLYYYSKDGSKCQWTLPEALVPPGQPMNGNGVEQDGPPVLNNWRYTQFNISQEDLKFSPSHRRIASDNASDASSSGNS-----------PESQHYDKKFRRRRN-LSSYSTDSHSHHSSLEKAGILNKTKVAENGKRLR-KNWAQSWTVLHDGVLTFHKDPKFAPAG-MSSKTNQIVPEYTVELKGATLSWASK------EKSSKKNVLELKTRHGSE--------------------------------------------------------------YLIQYDTDSIIQDWQKIILDTIKLLHEHGHNSEDEAEDVP-----EKSPLPAD-------------KEKKPEAARLSSTSS-IDTDQGRVRTKLRKF----LQRRP-----TLQSVKEKGYIKENVFGCHLDTLCHRENTTVPKFVEKCIRSVEKR--GLKIDGIYRVSGN-LAVIQKLRYKADHEED-----LDLED--GQWEEIHVITGALKLFLRELPEPLFPFSFFDKFIAAIQISDYSQKV---------------------SYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFGPTLLRPQEE-SNITMHMVFQNQIVELVLNEFNELFQTK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JCF3-1", "uniprot_id": "X2JCF3_DROME", "id": "X2JCF3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTTTSQRPVTPGTPDSAHIVIGAAGFVAHERRQPGK--------------------------------------------------------------------------------------------TLMNCFRDRSTTSSS--------------------------------------------------------------SSQAQHAYVRG-------------------------HSVTSSTLFRLEGSGGSNCTLDKAGKQ--------DTGRPEAVVLLRELKTRPN------------------------KLALLKSSSSKD----------------------------LTRLFLDDSTNTAVLVSNTSIDVCSSNSSSG------------GSP---------------------AVGRSKSGRDRRNGLECCSSCSKRWHDLKQRMHTLEQDLLVQTT--YSQELEQKVGEMSRQLTELLQERDRERDKDKARFAAAGGVAAPG-------KRTAHGSPNVRPSR---LVAWMNLSN--------------------------------------------------------------------WFKSRPS----------------------------------------------------------------------------------------------------------------------VETLREQRIFFDEPCFDT-----------------ELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIEGIYRQC------GDYNKIQTLRFS-IDAND--------------------------------------------------------------YDSLRQPDVDIHTLTGVLKLFLREIKSPLVRVNEAKTFIG-------------------------------------QPNQWLLTDLSAKLDSLKRL----IRSLP-----ESN-RDTMDYIFGHFNRITKVPLQQISAETLSISVTPSIFHTVPQ--GVHMQDIQQLLREGETLADCVKLMIEYQGR-----IFDRL--RLIQTAHLLCRCVERFANHSKSEILNPKPNTPLYLPHLYTHSRFAP---------------------ESVSNPDHIVYRCTADRRRLSMRNLKKTLSQPD------------------------------LLFHNLF---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38339-1", "uniprot_id": "RGD1_YEAST", "id": "P38339-1", "name": "RHO GTPase-activating protein RGD1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEETAKKPASATVSAKSSHDGGTDDLAHLFSTPEIKKVLN------------------------------------------------------------------------------------------SDVAINALLSRLKQS------------------------------------------------------------LLTCEEFMKFIRKKYAFE----------------EEHVQELSKQYKHFFNIQGSTNSSLKKMIHEVLGFDGKMAQVKQSYITALQKMYSEIS--------------------SLLLTMTKLRKSVKENSK----------------------------RLEKDVSDAIHSAEKAQSRYNSLCQDWDK--------------------------------------LRMTDPTKTKLTLRGSKTTKEQEEELLRKIDNADLEYKQKVD--HSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLN---TGVTISPLDSTKSMKSFAGSVSNER--------------------------------------------------------------------DLYSFLN---------------------------------------------------------------------------------------------------------------------KYNQTGKHSLLINKNLIPVS--------------YKKHPSMNHGQKNKSPPKFAVDPSRNSIPKRMISTHNESPFLSSS------SNTAAVPNANLNSATPSL--------------------------------------------------------------NTNKQLPPTMASSISSTSNAAGAMSPSSSIVTSDTTSSIT--------------------------------KTLDPGNNSPQIPEELINSLDSDRP----ISHIQ-----TNNNMPPGVQKNFKTFGVPLESLIEFEQDMVPAIVRQCIYVIDKF--GLDQEGIYRKSAN-VLDVSKLKEEIDKDPANISMILPSKP--HSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRK---------------------NFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDAN---DVNFQIMAMEVLLEVSDQAFEPE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39960-1", "uniprot_id": "BEM2_YEAST", "id": "P39960-1", "name": "GTPase-activating protein BEM2/IPL2", "aln": "MKGLLWSKNRKSSTASASSSSTSTSHKTTTASTASSSSPSSSSQTIRNSTSGASPYMHSHHHHGQGHSHHRGEDNNRDKRKSSVFPPSKQYTSTSSSQVNLGMYHSDTNTRSSRSIASTLKDDSPSVCSEDEISNSSSQKSNAQDETPIAYKKSAHSKDSLLPSRSSSLSPPQSRCSTGTTLEKSLNTSGISNSSGTNNNNSNNNNDNEQKQRNVIHLNSENYDTTVFKTGWVNKSHGQTVATNYNSSMTAPSSSSSSSSQNLRNDAYSRNRESRFYGNDGSSLKNDDSSSTTATNSGNDVASARSSMAIDPQMLVPDYRLYRAQLKGCVLNLYKSGLNSNIKFFDPTLPASNSSIANENHQQKKQQTNNQAQAEALHQKQSFGQMGEPITLDLKYLSEVYPHPDLRQDSDGKIISGTIESLCHTVLFYPGPKQSDVPNEKSLSKTHRAVINLLLMFPLLDHFIKFLKVFNQFGLSFTKNKSRLTNNSTQFYNISPAVDDSMTQRLALTAKTILDVFPGFLLDEPMLKTIISLLDTISLHNDEISNNLKIKIANKHNELMKLTAFTRSLPMATSSTHELEIILDPSHFLSLDITTLADEVHHINLKFDKVWAPKFDYSLLYDSKFINRRIVSLNPLVFNNDQNIHFLGRLLISHLFPTNPEFSKKVTPKVRAELLDKWVQIGCRFEHLGDMVSWLAVATIICSIPVLRSSSWKYVPDQSLKTIFKDWVPTIIQLERRQRTSKSTSSVFILAPPNLDDDFTRANVISYFGDLLIHADDLPSDTKFKYLEKKINRTKNAFHKWQQRLQAIDSTRHKTNSTENVRDNDSPNNVVYQLWKFHLSQPPLNIEGIMKLSVQHEPPIIDQKAYSTIGSQRSALVTGSYLPILFNELFPNYSLFPKNTLVGAASDAKLPPPRSSARLSKSLSISEPIPIASNSHTMGSLTDDAMSSKNDNNKVTGVGKIDGPVIKEMSSKQSNKQRLLKSVRDVFNIDMDVFHISDELVFKSVYDNDGKSRPASMVIETPKRFSQHSSMLINNPATPNQKMRDSLDTTGRLSKTLENMDFFNNIGQVSDSLKESIIRVVLKSSSLEKIFDLLVLTSNIFSKLVDTKDLENYYYHQRQRGHSTRGLSDDNIGLLDYAFVKLTMDNDIFTETFFNTYKSFTTTTTVLENMAKRYVGAKSCSVSISKILDRSDDSKMKINEDTNLVSSSLYDQNFPVWDMKVTDDENINLIYMAKIQIGAAEAILHLVKNHYSDFTDDLCNNSTLLDIIKIMEQEVSTEWPTRIANSKLQKSLPENFVIETENLLTTLTDLFHGIKSAYQKQLYRPIGVNRTQKRITDILNSFNTFSFTDLNNIIDDPSFSDDMIRSFQKLHSTNYEDILEWIYQLDNFISKKFNLVSKKDWIVLFQELELLSKESLVSFFNYPLHFKSSKLINPGYLQLHEFEISNLFTWISTLILKDDNGTESLFFEKLPQSIKLLIKLHTSLTTFFVMEISNVNKSSSERLTTCKVILQILNYIRWKNGSLDLFDSEEDESPHAICPHIPAFIETAIAHAIISPESRNYELSWIKASEKLSDPTKGTQNLRSISNVLEKIDDIHIKRFIEIDDVFSKNCKNLCPCPGWFISRLLEISQFVPNMSITNSKLINFDKRRFVNNIISNVLDLIPNEREFPLDIEMSDENPSKRTTFGRILFNNFEDVNKVYRKKTKKVSESEAISERFQEQGVFNEILVNEIEKIKREARKLEVLLDQEKILKNSAALHQAVPKKNRKSVIISGTHSDNDHSYNINKNTGQTPSLGSVMESNNSARNRRDSRASFSTNRSSVVSNSSHNGVSKKIGGFFRRPFSIGGFNTSSSNYSLNSILSQEVSSNKSILPSILPEVDSMQLHDLKPSYSLKTFEIKSIMEIINHR-----------NIPAYYYAFKIVMQNGHEYLIQTASSSDLTEW----IKMIKASKRFSFHSKKYKGKTHNKIFGVPLEDVCERENTLIPTIVVKLLEEIELR--GLDEVGLYRIPGS-IGSINALKNAFDEEGATDN-SFTLED--DRWFEVNAIAGCFKMYLRELPDSLFSHAMVNDFTDLAIKYKAHAMVNEEYK----------------RMMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLAIVFSMSFINQEDLANSMGSRLGAVQTILQDFIKNPNDYFKQ-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06407-1", "uniprot_id": "RGA2_YEAST", "id": "Q06407-1", "name": "Rho-type GTPase-activating protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSADPINDQSSLCVRCNKSIASSQVYELESKKWHDQCFTCYKCDKKLNADSDFLVLDIGTLICYDCSDKCTNCGDKIDDTAIILPSSNEAYCSNCFRCCRCSNRIKNLKYAKTKRGLCCMDCHEKLLRKKQLLLENQTKNSSKEDFPIKLP-----------ERSVKRPLSPTRINGKSDVSTNN---------------------------------------------------TAISKNLVSSNEDQQLTPQVLVSQERD---------------ESSLNDNNDNDNSKDREETSSHARTVSIDDILNSTLEHDSNSIEEQSLVDNEDYINKMGEDVTYRLLKPQRANR----DSIVVKDPRIPNSNSNANRFFS-----------------IYDKEETDKDDTDNKENEIIVNTPRNSTDKITSPLNSPMAVQMNEEVEPPHGLALTLSEATKENNKSSQGIQTSTSKSMNHVSPITRTDTVEMKTSTSSSTLRLSDNGSFSRPQTADNLLPHKKVAPSPNKKLSRSFSLKSKNFVHNLKSKTSEMLDPKHPHHSTSIQESDTHSGWGVSSTHTNIRKSKAKKNPVS--------------------------------------------------------------------RGQSDSTIYNTLPQHGNFTVPEFNHKKAQSSLG-----------------------------------SISKKQNSNDTATNRRING------------SFTSSSSGHHIAMFRTPPLESGPLFKRPSLSSESAHHRSSSLQTSRSTNALLEDDSTKVDATDESATSLEKDFYFTELTLRKLKLDVRELEGTKKKLLQDVENLRLAKERLLNDVDNLTREKDKQSAS-------------------------------------------------------------SRESLEQKENIATSITVKSPSSNSDRKGSISNASPKPRFWKIFSSAKDHQVGDLE-----------SQQRSPNSSSGGTTNIAQKEISSPKLIRVHDE----LPSPGKVPLSPSPKRLDYTPDGSHLYGSSLQARCAYEKSTVPIIIRCCIDRIEKDDIGLNMEGLYRKSGS-QTLVEEIENEFAQNNSLHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERNLMNLHNLSLVFAPSLIHDFDGEKD-IVDMKERNYIVEFILGNYRDIFKQA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39083-1", "uniprot_id": "RGA1_YEAST", "id": "P39083-1", "name": "Rho-type GTPase-activating protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTAPNEQFPSCVRCKEFITTGHAYELGCDRWHTHCFACYKCEKPLSCESDFLVLGTGALICFDCSDSCKNCGKKIDDLAIILSSSNEAYCSDCFKCCKCGENIADLRYAKTKRGLFCLSCHEKLLAKRKYYEEKKRRLKKNLPSLPTPVIDN---------------GHTDEVSASAVLPEKT---------------------------------------------------FSRPASLVNEIPSGSEPSKDIETNSSD--------------IVPHFITGYNDSDDNSGSSKFGSNVSIDVIGPEENSTEHVNDDVKEEAEAPSANMSLNVATDPTLSCKEPPSHSR-----NLLNKTPLRNSSGQYLAKSPS--------------------SYRQGIIVNDSLEESDQIDPPNNSSRNASELLTSVLHSPVSVNMKNPKGSNTDIFNTGEISQMDPSLSRKVLNNIVEETNALQRPVVEVVKEDRSVPDLAGVQQEQAEKYSYSNNSGKGRKISRSLSRRSKDLMINLKSRATGKQDSNVKLSPASKVTSRRSQDLMRDNDSHTGLDTPNSNSTSLDILVNNQKS------------------------------------------------------------------LNYKRFTDNGTLRVTSGKETALEEQKNHSFKSPS-----------------------------------PIDHLLQSPATPSNVSMYR--------------------TPPLDSSLTFDRRNGSSYSNQNYSIPSWQKTPKTQLENSDNFEEQKETLYENSESRNDPSLDKEIVTAEHYLKQLKINLKELESQREELMKEITEMKSMKEALRRHIESYNSEKNKLYLD------------------------------------------------------------SNELSNNPPMINEISLGESPPVKHVATASSVARSSVKPKFWKFFSSAKPQTEQSIQGVSTNNTNSIVKSAPVLLSAPSSGSNSGRLEISPPVLQNPNEFSDVRLVPIENDANMGQSKDGEEYLDGSNLYGSSLVARCNYENNEIPMILSVCIDFIESDEENMRSEGIYRKSGS-QLVIEEIEKQFSAWKVQQN---TETPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLIRDFSGEKD-IIDMKERNYIVAFIFGNYKDILT--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . . . . : . : : . :. : : .: .: : . . :. : .: : . :: : . : : . :: :. : ", "identical_positions": 0, "similar_positions": 44, "identity": "0.0%" }, { "cls_id": "homologset.agr.HGNC:31814", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2G1-1", "uniprot_id": "D4A2G1_RAT", "id": "D4A2G1-1", "name": "", "aln": "MGQTPALERCSAQLDAFPQLLRPQGMDAATAPKQAWLLWSPLLFLLLLPGGSISSCPTLCDCTSQTRAVLCAHRRLDTVPGGLPLDTEVLDLSGNRLWGLQRGMLSRLGQLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIVGPGIFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQQLEVGDNHLVFVAPGAFSGLAKLSTITLERCNLSTVPGLALAQLPALVALRLRELDIERLPSGALRGLGQLKELEIHHWPSLEALDPGSLVGLNLSSLAITHCNLSSVPFQALHHLSFLQVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPACAGPQHVQGKNLREFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPQGSWLGRVGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNVTMPGIPGPFSLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHHMTFDFVAPRPSGDKNSGGNRVTAKLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q149C3-1", "uniprot_id": "LIGO4_MOUSE", "id": "Q149C3-1", "name": "Leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4", "aln": "-------------------------MDAATAPKQAWLPWSPLLFLLLLPGGSISSCPTVCDCTSQTRAVFCAHRRLDTIPGGLPLDTELLDLSGNRLWGLQRGMLSRLGQLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIVGPGIFSGLTALTLLDLRLNQIVLFLDGAFSELGSLQQLEVGDNHLVFVAPGAFAGLAKLSTITLERCNLSTVPGLALAQLPALVALRLRELDIERLPAGALRGLGQLKELEIHHWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALHHLSFLRILDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPACAGPQHVQGKSLREFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPQGAWLGRVGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNITMPGIPGPFFLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHHMTFDFVAPRPSGDKNSGGNRVTAKLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UY18-1", "uniprot_id": "LIGO4_HUMAN", "id": "Q6UY18-1", "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4", "aln": "-------------------------MDAATAPKQAWPPWPPLLFLLLLPGGSGGSCPAVCDCTSQPQAVLCGHRQLEAVPGGLPLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRHLDFGMSPPACAGPHHVQGKSLKEFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPHGAWLGRAGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNITVPGIPGPFFLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHHMTFDFVAPRPSGDKNSGGNRVTAKLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********** *.************ .***::******.:**:*.**:*:::*********:************:******. *************************************:***:****:********************.******:****************:*******:****************:************** ***:*************** ***********************:***********:*****::**********************************************************************************************:**** ********:*****.*:*****************************************************:*:****.*********************************************************:*:******* *******************************************************************", "identical_positions": 548, "similar_positions": 37, "identity": "88.67%" }, { "cls_id": "homologset.agr.HGNC:31816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXX0-1", "uniprot_id": "IQCF3_RAT", "id": "Q6AXX0-1", "name": "IQ domain-containing protein F3", "aln": "MELDQDQKVETPEAAENGKDEMQLEEQTQDEDTTETETETETETEAEAEGADGTILERTESVKAKLVPQAEKQIQDEKTGIKEADRAIQEQTQDDETEAEGADGAILKRSESVKVKLIPQAEKQIQDEKTGIKEADRAIQELPANAELAGVKIQAWWRGTLVRRTLLLAILSAWTIQSWWKETKSRLQG-RKLHDVMRCRLRNLNLKSISRRKRPNQSSFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7M6-1", "uniprot_id": "IQCF3_HUMAN", "id": "P0C7M6-1", "name": "IQ domain-containing protein F3", "aln": "-----------------------------------------MGSKCCKGGPDEDAVERQRRQKLLLAQLHHRKRVKAAGQIQAWWRGVLVRR--------------TLLVAALRAWMIQCWWRTLVQRR--IRQRRQALLRVYVIQEQATVKLQSCIRMWQCRQCYRQMCNALCLFQVPESSLAFQTDGFLQVQYAIPSKQPEFHIEILSI----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. *.* :** . * *. .:: . *: *.: : :::. :* : : :.: *:: :*: .: . * * **:*: * *: : :* .. : :* ::: .: .: ::::: :* ", "identical_positions": 21, "similar_positions": 54, "identity": "9.5%" }, { "cls_id": "homologset.agr.HGNC:31817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62855-1", "uniprot_id": "RS26_MOUSE", "id": "P62855-1", "name": "Small ribosomal subunit protein eS26", "aln": "MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPP--PRFRPAG-AAPRPPPKPM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62856-1", "uniprot_id": "RS26_RAT", "id": "P62856-1", "name": "Small ribosomal subunit protein eS26", "aln": "MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPP--PRFRPAG-AAPRPPPKPM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JNZ5-1", "uniprot_id": "RS26L_HUMAN", "id": "Q5JNZ5-1", "name": "Putative ribosomal protein eS26-like", "aln": "MTKKRRNNSHAKKGRGHVQPIRCTNCVRCVPTDKAIKKFVIRNIVEAAAVRDISEVSVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREACKDRTPP--PRFRPAG-AAPRPPPKPM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JVP7-1", "uniprot_id": "A0A0G2JVP7_RAT", "id": "A0A0G2JVP7-1", "name": "40S ribosomal protein S26", "aln": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSP--PRFRPAG-AAPRPPPKPM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13008-1", "uniprot_id": "RS26_DROME", "id": "P13008-1", "name": "Small ribosomal subunit protein eS26", "aln": "MTKKRRNGGRNKHNRGHVKPVRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDITEASIWDSYVLPKLYAKLHYCVSCAIHSKVVRNRSREARRIRTPP--LRSFPKD-MARNNQNRK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39938-1", "uniprot_id": "RS26A_YEAST", "id": "P39938-1", "name": "Small ribosomal subunit protein eS26A", "aln": "MPKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPPQRPRFNRENKVSPADAAKKAL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39939-1", "uniprot_id": "RS26B_YEAST", "id": "P39939-1", "name": "Small ribosomal subunit protein eS26B", "aln": "MPKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPPQRPRFNRDNKVSPAAAAKKAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*** ...: *:.****:*: *.** .:*.*****::.* ****:*****::*. :: *.*** * ******* ***::::* :*:* : *:.* * . : : ", "identical_positions": 51, "similar_positions": 35, "identity": "42.86%" }, { "cls_id": "homologset.agr.HGNC:3182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHM8-1", "uniprot_id": "A0A8I6AHM8_RAT", "id": "A0A8I6AHM8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MFPQPPRRVQRPGLMG--LESEHHSWGPWNAIMETESEQNSSSTNGSSSSGASSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNSSTAQQQTATTQASINLATTSAAQLISRSQSVS------------SPSATTLTQSVLLGN----------------TTSPPLNQSQAQMYLRPQLGNLLQVN-----------RTLGRNVPLASQLILMPNG-----------------AVAAVQQEVPPAQSP-------------------------GVHADADQVQNLAVRNQQAS-----AQGPQIPGSTQKAIPPGASPVSG-LSQASSQALAVAQAS------GASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGG------------------------------------------------------------------------------------LGQLPSSGLAGGNCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAE-------------------------GDGSSQQSVGMNLTRTATPAPSQTLISSATYTQIQPHS-----------LIQQQQQIHLQQKQVVIQQQ------------------IAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQATTLAAPQPPQVPPTQQVPPSQSQQQ------------------------------------------------------AQTLVVQPMLQSSPLSLPPEPTPKPP------------------------IPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRG-----------------------------MPGAVQPGQAHLASSQP--------------------------SSQ-APGALQECPPALATGMTLAPVQGTAHVVKGGPTASSP-------VVAQVPAAFYMQSVHLPGKAQTLAVKRKAESEEEREDLSALGSVLPTKASPAAESPKVIEEKNSLVEKAEPVASLNANPPNSDLVALAPTPSAPPPTLALVSR--------------------QMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETEKPLPAGLPTGLNESQSGGPLGGDSPCVDLDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKR---------KKMKEFQEASYARVRRRGPRRSSSDIARAKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64028-1", "uniprot_id": "PHC1_MOUSE", "id": "Q64028-1", "name": "Polyhomeotic-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSSSTNGSSSSGASSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNSSTAQQQTATTQASMNLATTSAAQLISRSQSVS------------SPSATTLTQSVLLGN----------------TTSPPLNQSQAQMYLRPQLGNLLQVN-----------RTLGRNVPLASQLILMPNG-----------------AVAAVQQEVPPAQSP-------------------------GVHADADQVQNLAVRNQQAS-----AQGPQMPGSTQKAIPPGASPVSG-LSQTSSQALAVAQASS-----GASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGG------------------------------------------------------------------------------------LGQLPSSGLTGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAE-------------------------ADGSGQQSVGMNLTRTATPAPSQTLISSATYTQIQPHS-----------LIQQQQQIHLQQKQVVIQQQ------------------IAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQ-------QQGTTLTAPQPPQVPPTQQVPPSQSQQQ------------------------------------------------------AQTLVVQPMLQSSPLTLPPEPTSKPP------------------------IPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGSAQAQALGLAQLAAAVPTPRG-----------------------------ITGAVQPGQAHLASSPP--------------------------SSQAAPGALQECPPALAAGMTLAPVQGTAHVVKGGPTASSP-------VVAQVPAAFYMQSVHLPGKAQTLAVKRKAESEEERDDLSALASVLPTKASPAAESPKVIEEKNSLGEKAEPVASLNANPPNSDLVALAPTPSAPPPTLALVSR--------------------QMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETKKPLQAGLPTGLNESQPSGPLGGDSPSVELEKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKR---------KKMKEFQEASYARVRRRGPRRSSSDIARAKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78364-1", "uniprot_id": "PHC1_HUMAN", "id": "P78364-1", "name": "Polyhomeotic-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVS------------SPSATTLTQSVLLGN----------------TTSPPLNQSQAQMYLRPQLGNLLQVN-----------RTLGRNVPLASQLILMPNG-----------------AVAAVQQEVPSAQSP-------------------------GVHADADQVQNLAVRNQQAS-----AQGPQMQGSTQKAIPPGASPVSS-LSQASSQALAVAQASS-----GATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGG------------------------------------------------------------------------------------LGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAE-------------------------ADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHS-----------LIQQQQQIHLQQKQVVIQQQ------------------IAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQP------------QATTLTAPQPPQVPPTQQVPPSQSQQQ------------------------------------------------------AQTLVVQPMLQSSPLSLPPDAAPKPP------------------------IPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRG-----------------------------MPGTVQSGQAHLASSPP--------------------------SSQ-APGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSP-------VVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSR--------------------QMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKR---------KKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W523-1", "uniprot_id": "Q9W523_DROME", "id": "Q9W523-1", "name": "", "aln": "MPHGFGAAPSVSVSGDTESESATTIRTPPPS--------PEATTSVKVNSTTRVDP--------------------------------QRPLRCLETLAQKAGISFDEDFAKSPSQSP---SSKAARGS---------------VGTPSIRRRHPLLPLSSRSPSAPDS---------KTTGRKLEKSQSPAQQVAAATNVPLQISPEQLQQLYANNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPSNHNQSPQTVLISPVNVISHSPQQQQNLLQSMAAAAQQQQLTQQQQQQLNQQQQQLNQQQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSTVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFWQNAAGLQPFGSNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQHILQQQ-MLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSTGATSQQQQQQPQQQSGQLQLSSVPFSVSPSMTAEDIAGITSSALQEALSVSGAIFQTTKPITCSSSTLPTSSVVTITSQSSTPLVTSSTVASMQQAQTQGTQIHQHQQLISATIAGGSQQQQQQQQLGLPSLTPTTPSPTTNPILAMTSMMNATVGHLSTAPP--VSVSSTAVTPSSGQLVTLSSASSGGGAGFPATPTKETPSKGPTATLVPIDSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKLTTCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAP-------GSDMVACEQCGKMEHKAKLK-RKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTESYQTVSDALPIQAATPEVPPISMPVLAAMSTSSPLSLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNINGSDRPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKEVPP-GDVKD----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39769-1", "uniprot_id": "PHP_DROME", "id": "P39769-1", "name": "Polyhomeotic-proximal chromatin protein", "aln": "MDR--RALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVIS--PQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQ--LTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIA--TSSALQAALSASGAIFQTAKPGTCSSSS-PTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQ----GPPSLTPTT-----NPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAP-------GSDMVACEQCGKMEHKAKLK-RKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAP-----KSSEVNGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:* : :*. . . . .. *: . * *. * : : . ..:: * : : .: **:. : :. *** *... :.: .**: * * ::* *. ** : : .*. .**:: * .:::.. *:. *:: . .** . . :. : * :.* :*:. *.** **::. *. **.*:.. .*::. : :* * ** ****. .. . :*::.*.: *:*:: * : *: :* :** .. .:* ..* *. * **.::.: ..* . .* **:.. * : .*: :: :* : **. . ** :....* .: :: *:* * * :. : :****::* *** ::*** : ::*** * *.* ::: : :***** * ****:: *. : :: * **.*.* :.. *.*** * * **. * *.. . . .. * :** ... .. .:. : *...* :. ..*.: * . :*. : * :.. . * :.. ::. .**::: * .. *.: : .*: .. **.*: .. *.* * ::* * *.* *: .. *... : . . : .. * . *:.: * : * * : : . :...:. .:.. .. : . .:.*.. .* : .: . *... *:*::**::***:*:**:***. ***** .: .: . . : : *. . :. . :::: ** *** ::: **:** *::: : *.... * :..::** . : . . *: . . .: .:. ::. * .::: . : .. . . * ***::* :** .* ***: .::* .*************:**:.**.:******** **:: :**. ", "identical_positions": 235, "similar_positions": 364, "identity": "14.51%" }, { "cls_id": "homologset.agr.HGNC:31822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1H2-1", "uniprot_id": "D4A1H2_RAT", "id": "D4A1H2-1", "name": "", "aln": "------------------------------------------------------MASSQGKNELKFADWMATLPESIHSIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMSFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVF--LDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFA--QEVSLKYLWEKSYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQAS--ITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWIRTQKPG------ESGINIVTADFVELG--DFISTVIKLNYVFDEGEANT----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLJ3-1", "uniprot_id": "PLCX3_MOUSE", "id": "Q8BLJ3-1", "name": "PI-PLC X domain-containing protein 3", "aln": "------------------------------------------------------MASSQGKNELKFADWMATLPESIHSIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMSFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVF--LDFNHFYGMQKYHHEKLVQMLKNIYGNKMCPAIFA--QEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQAS--ITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWIRTQKPG------ESGINIVTADFVELG--DFISTVIKLNYVFNEGEANT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HM9-1", "uniprot_id": "PLCX3_HUMAN", "id": "Q63HM9-1", "name": "PI-PLC X domain-containing protein 3", "aln": "------------------------------------------------------MASSQGKNELKLADWMATLPESMHSIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVF--LDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFA--QEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQAS--ITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPG------ESGINIVTADFVELG--DFISTVIKLNYVFDEGEANT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EK3-1", "uniprot_id": "PLCX3_DANRE", "id": "Q58EK3-1", "name": "PI-PLC X domain-containing protein 3", "aln": "------------------------------------------------------MASSQGKSELRYADWMSSLPDTLHGIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMNFTSQLEAGIRFFDLRISTKPRDPDNELYFAHGLFSATVREGLEQISTFLASHAREVVF--LDFNHFYGVQNLHHEKLVQMLRTVFGDRLCPVVFA--QEVSLKYLWEKEYQVLVFYHNPMALEVPFLWPGQMMPAPWANTTDPEKLILFLQAS--VKDRRRKGTFFVSQVVLTPKASTVMKGVTSGLRETITERALPSMMQWIRSQRPG------ESGVNIITADFVELG--EFISAVITLNYYLDDEEENAT---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIP3-1", "uniprot_id": "Q9VIP3_DROME", "id": "Q9VIP3-1", "name": "Phosphatidylinositol-specific phospholipase C X domain-containing protein", "aln": "---------------------------------------------------------------MSKDHWMRDLPSELRDLSIINLAIP-----GSHNSMTYGINSK-------------------------------SELSPDAEISIRRWHR--------------------------------------------------------------------------FFP----CFVRRWSKTQSSGTLDQLELGVRYFDLRIAQK----DDKFYYCHGLFAMEIFEPLLEIRQFVDTHPEEVVI--LDLQHFYAMTVAHHQKLHKDLIQFFAHRLYSTVDGSLKDCTLNRCLEMQRSVVIIYRRCPIPLPLRFWPSYAWPTPWPNKASVKKLQSFLEDS--LLSRQPQ-QGYVSQCLITPTGRYIAFRLFFTLKS-TAKRVDKKLQPWIQEQIPGPFEPKDEPRVNVFLADFVSLKGGQFCDWVVDLNTKLLEQLAGDKELESTEGVEEEEAQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKC3-1", "uniprot_id": "Q9VKC3_DROME", "id": "Q9VKC3-1", "name": "", "aln": "MVGKVLRLALVLLLLASWTNEGRAQTESYENPKALKVWLTISARKRFLEVSWSNAPANKGDQLLVTREDALSFQSQLLRKHTPLAGFPSEEGSGSGDGSPSYVPNSGFTARPATKAASKEEEQEQYWVANGGATEVVAAIEPRQGLSTQWFTTGLPFDYALSRNATVQTACYGFWASYIDAQGNILAKTCLKVFPRWMNDLKSKIGEMRLRDLFIPGTHDSGSYRPNFDPLLRESLVTKYALTQDDDIRGQLMHGVRYLDIRVGYYRNSPDPFFIYHGITKQRPLQEVINQVRDFVYETNEIIIFGLKEFPVGFGKGLGVHRLLISYLRDQLKDLIAHPSLT--WGASLRDIWARRQNVFLAYDHEAMVEEFPDVLFGSVEQRWGNKQTWDQLETYLRNVNDFDVSRFSSRPVSDMAELTPETWDVILDKTGGLRKMADNVNWRISQLYRNELGTN---------ANIVSADFIRGT--TLVETAIEYNARKIYM--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : .:* ** :. . : . : : * : : : . :: :: ** . .** *:*::*:*:. * : : : * : :: *: . ::: :: :. *. * . * . : :*. .*.: * * *. .:* :*. . : . . :** : *:. : : . .. *:. ***: : . .: * ", "identical_positions": 33, "similar_positions": 79, "identity": "6.41%" }, { "cls_id": "homologset.agr.HGNC:31823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQM5-1", "uniprot_id": "KPRP_RAT", "id": "Q7TQM5-1", "name": "Keratinocyte proline-rich protein", "aln": "MCDQQEIQCCGPIPQCCVKGSSFGPSQFPYANNQVLVEAPCEMQFLECAAPCPIQVSQT----PCQSSTTEVKGQAPCKTTN----VKCQTKTTQVKCQPKTTEIKCQAPCQAQVSCVQCQAPCQSQVSYVQVP--QPPQTYYVECAPVYYTETRFVEYPVSNYVPVPAPQPGYTYVECPSLGQGQGQGS--FSTRYQYQGSYGSCTSQSQSRGSYSSCGPQHQSQASYSYCEPQFQSRPSYTNCGTQRQSQASFGSCTSQLQSRASYSNCSSQRRSGTSFSTCAPQCQGQGTYGSFTAQRKSQSASRCLPS-RRLQPSYRSCSPPRHSEPCYSSCLPSRCSSGSYNYCTPPRRSEPIYGSHCSPRGRPSGCSQRCGPKCRIEISSPCCPRQVPPQRCPVQIPPIRGRSRSCPRQPSWGVSCPDLRPCAEPHAFPRPCRPQRLDRSPESSWRRCPVPAPRPYPRPEPCPSPEPRPCPRPRPRPEPCPSPEPRPRPRPDPCPSPELRPRPRPEPCPSPEPRPRPRPDPCPSPEPRPRPCPEPCPSPEPRPCPPLRRFSEPCLYPEPCSVSKPVPCPVPCPAPHPRPVHCETPGRRP--QPSPRSQPCPHPEPMPRPVPCSSPVPCGDPIHCPSPCSGHNPVPYSQELGCHESNPCRLDTEGP--SSYSFSQGQESNGCCVSGGVFSGSRGLSGCGDQGNTYRGMNCGACGGTQGAYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RUR4-1", "uniprot_id": "KPRP_MOUSE", "id": "B2RUR4-1", "name": "Keratinocyte proline-rich protein", "aln": "MCDQQPIQCCVPIPQCCVKGSSFGPSQFSYANNQVLVEAPCEMKVLECAAPCPVQVSQT----ACQSSTTEVKGQAPCKTTKGKCQAPCQSKTTQVKYQPKTTEIKCQAPCQTQVSCVQCQAPCQSQVSYVQIP--QPPQTYYVECPPVYYTETRYVEYPVSTYMPAPALQPGYTYVECPAVGQGQGQGQGGFSTQYQYQGSYGSCTPQSQSRRSYSSCGPQNQSQASYSYCEPQFQSGPSYTNCGPQRQSQASYGNCTSQLQSRASYSNCSSQRRSGATFSTCAPRCQSQGTYGSYTSQRRSQSTSRCLPP-RRLQPSYRSCSPPRHSEPCYSSCLPSRCSSGSYNYCTPPRRSEPIYGSHCPPRGRPSGCSQRCGPKCRVEISSPCCPRQVPPQRCPVQIPPFRGRSQSCPRQPSWGVSCPDLRPRADPHPFPRSCRPQHLDRSPESSRQRCPVPAPRPYPRPQPCPSPEPRPYPRPQP----------------------------------------------CPSPEPRPRPCPQPCPSPEPRPCPPLRRFSEPCLYPEPCSAPQPVPHPAPRPVPRPRPVHCENPGPRP--QPCP----LPHPEPMPRPAPCSSPEPCGQPVRCPSPCSGPNPVPYRQELGCHESNPCRLDTEGPRCGSYNFTQRQESNGSCESGDVFSGSHGLSGCGDQGNTCGGMNCGAYGGAKGAYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T749-1", "uniprot_id": "KPRP_HUMAN", "id": "Q5T749-1", "name": "Keratinocyte proline-rich protein", "aln": "MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQVKCQSKTKQVKG-----------QAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGR----FSTQCQYQG-------------SYSSCGPQFQSRATCNNYTPQFQLRP--------------------------SYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCP-RRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP--------------------------------------------------------------------------RQLSEPCLYPEPLPALR----PTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGPGDVFPERRGQDGHGDQGNAFAGVKG----EAKSAYF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** *** *: ******.** .** .:*:.**:*:*****:.::*.*.**:**.*. .***.**:** *: * .: *.: *.***::* **..*:*.*.**.******:***** ** ** :***.** **** :** **..*:* ** ** * *:: * **: ***: **** ******** **:*: . **** * ***.* .* ** ::**.*.*:** **:***:* *::*:*:*****. **** *******: *** ** ** * *.* *************.*:*. * *.**** *****:******************:***:* **:** *****.***:*** .:*:.:* * *::**:.***. :*** ***** **:** * **** * * *::********* .. : *.* *.* *** :** * ** **. *:***:* *.**.** ** :. :.**** * ***** :******.* *****.* .. .:.* ***.. * .*.**. :* .* *****: *:: ::.***", "identical_positions": 336, "similar_positions": 125, "identity": "46.93%" }, { "cls_id": "homologset.agr.HGNC:31824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTC4-1", "uniprot_id": "A0A0G2JTC4_RAT", "id": "A0A0G2JTC4-1", "name": "", "aln": "MSQQKQQPSELPNAPKCSPPKGPNFCLTSCSSSCGTSCSAGYSSQLRRLGLRNTANRKKIHHPQPRCLRGGTTYHCKEEEC---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YV94-1", "uniprot_id": "D3YV94_MOUSE", "id": "D3YV94-1", "name": "", "aln": "MSQQKPQLSELPNAPIYSPPKGPNLSLSTCSTSCGTSCSAGCSSYSKRLRLQNTVSHKEIHHPQPRCLRGSTTYHCKEEEC---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A183-1", "uniprot_id": "LCE6A_HUMAN", "id": "A0A183-1", "name": "Late cornified envelope protein 6A", "aln": "MSQQKQQSWKPPNVPKCSPPQRSNPCLAPYSTPCGAPHSEGCHSSSQRPEVQKPRRAR----QKLRCLSRGTTYHCKEEECEGD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** * : **.* ***: .* .*:. *:.**:. * * * :* :::. : : *** .********** ", "identical_positions": 34, "similar_positions": 19, "identity": "40.48%" }, { "cls_id": "homologset.agr.HGNC:3183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8QHL5-1", "uniprot_id": "PHC2_DANRE", "id": "Q8QHL5-1", "name": "Polyhomeotic-like protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKEQEQGSVASSASVTIPSTTSVS----------TSTSAGTLSNSSSR---QQTVPQISVYGGITDRQTVQVIQQALN------------------------------------------------RQPSTVAAQYLQQMYAAQ----QQHLMLQTAALQQQHLS------LAAVQQAS---------IVAGRQSCSQHGSTSQQTVASQTTINLATSPAARHLISRAQSGSSVPVC-IGQQAVLLGNSSTPTLTASQAQMYLRAQMAQQTNLVQVARSLGRAVPL--------------SSQLIFTPTASVTAIQPEAPAPSINTPPTSGQVQNLALRSQQGA--------LTSTLSQSQLQSLSVKQSVASVTGQSVARLKGLGAEPSPQGTAAKASPAETSSETTAKNDKTS----DLTTSVCPSVT---SVAGHPFISTAYTQIQT---HQLLQQ----HKQ-QFVIQQQPQI------------------------------------------------------------------------------------------------------------LQRGQAQ-LLEAAAIHPHTVQA-VAIQSALPAQP--------------------------QQCPIPLLPKVPVTCQQATIFHSTTVSQQALAQNGQAHILTHTKAPPLQLT-AVKCQIHPVQIQ--------------QGVASQNVPDKDTPVLLEPQLLSIPIQEPTRTELRQSDKES-----QVKENTQGSVNVK-----------------------------AGVGSPPAMTSGSGNNAP------------TVTGSAPQNGESKPPPQAVVKPQILTHVIEGFVIQEGAEPFPVERPSLLIENLKQKQHHAYSDLQKHN-------ADSEMEDLSLQELNNQPE---PVRTCEFCGNVDFAFNFKRSKRFCSTVCAKRYNVGCTKRMGLFP---GKSSPEDTKKPKASDESPKNCSTETRKRNPSIQTTTGASLLSPHPSHPSHGESSQCSDMSSYEEPISPLSNSSFGAPIEHE----ESFDHSRELTPLLTQHFLASDPTKWNVEDVYEFICSLPGCHEIAEEFRSQEIDGQALMLLKEDHLMSTMNIKLGPALKIFARISMLKDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F6P2R0-1", "uniprot_id": "F6P2R0_DANRE", "id": "F6P2R0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLTTGPNGARAAPQKSLRRVWQRGSRGSKVKHRGGTMEGEQSTPAASASSTTGTSTSTTNSTGTTSASTASTASSTSSSTSSA---RQAVPQISVYSGIPDRQTVQVIQQALN------------------------------------------------RQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSTAQLQSLAAVQQAS---------LAAGRQSSNQNGTSSTQSGSSQTTINLTTSPAAAQLISRAQSVNSAPSG-ISQQAVLLGNASSSTLTASQAQMYLRAQMAQQSNLVHVARSLGRAVPL--------------SSQLILAPTATVTALQSDTNT-TNNTQSASAQVQNLALRNHQG---------VSSTPQATGLQALSLKQTPVSIQPTPLIKT------PSQSTGAGKNNLNAASSDGVKKAEEGQ----TEMKAVNMSRN---VSSSHPLIAPAYAQIQP---QALIKQ----QPQ-QFVIQPQATP------------------------------------------------------------------------------------------------------------TSRSQPQ-LLQTASIQPHQQTASLGIPSSAQTST--------------------------VTGIIPVLPKPALHNQGSAQTQQATIFHSTVSHHAHT-ALAHAKAQPVQLT-AINLQIQPAQNQ--------------ASRLAQDDKEKPTSLVLREICPPVQIHPSTTTQGTDPPEQSKADTVNATSQTQGSVETAREP--------------------------TGAQLTSSMTSAVSSEPPP----------AAVMGNTTQNGENKPP-QAIVKPHVLTHVIEGFVIQEGAEPFPVERPPVAAESPKKPDTQLPSDPEKTASSNSLSATNSDTEEAGQQDTRVEEETEKPKLTCELCGWVDFAHKFKRSKRFCSMVCAKRYSVSCTKRVGLFRPDRTKSTNQINQWRRRRSHSPRGREAKKQRLSVSQQSQ-GESISSPLQSQPSQGESSPCSDISSYEEATSPLSAASSGPVVSQG----VVAANEPEELPLLSQHFLPCDPTKWNVQEVFEFIRSLPGCQEIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIFARINMLKDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A0M3-1", "uniprot_id": "D4A0M3_RAT", "id": "D4A0M3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSRASITTNTSGTN---------SSSGCSSSSGGGSG---RPTAPQISVYSGIPDRQTVQVIQQALH------------------------------------------------RQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVANRQGSTSGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSATASGLAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAAAAAASGPAPTQPVLPSLALKPTPSSSQPLPPTPQGRTVVQGSPVG--AKPSVTDNVTEPLKT-DGNS----NMEARPGPDRATVPTVATHQLTAPAYTQLQP---HQLLPQPSSKHPQPQFVAQQQPQP-----------------------------------------------------------------------------------------------------------PRPTPQVQSQPQLAAVSPSLALQPSPEGHAMPLGP--------------------------VTQALPLQCSTAHVHKPGSSQQCHLPTPDSGSQNGHPEGVSHAPQRRFQHTSAVILQLQPASPV--------PQQCAPDDWKEVVPAEKSVPVTRPGLSPHQQAIITAIPGGLPGPKSPNIQQCPAHETGQGIVHALT------------------------------DLSSPGMTSGNGNSAS------------SITGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLP-EKLPQQDHTTTTDSEMEEPYLQESK--EEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELSDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWH1-1", "uniprot_id": "PHC2_MOUSE", "id": "Q9QWH1-1", "name": "Polyhomeotic-like protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSNRASVTTNTSGTN---------SSSGCISSSGGGGGSGGRPTAPQISVYSGIPDRQTVQVIQQALH------------------------------------------------RQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVANRQGSTPGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSAAASGLAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELCTGSPARPPTPAQVQNLTLRTQQTP----AAAASGPPPTQPVLPSLALKPTPSSSQPLPAPPQGRTMAQGSPAG--AKPSGTDNAPETLKAGDGNC----NMEGRPGPGRA-VPAVATHPLIAPAYAHLQS---HQLLPQPPAKHPQPQFVAQQQPQP-----------------------------------------------------------------------------------------------------------PRPAPQVQSQPQLASVSPSLALQSSPEDHALPLGS--------------------------VTQALPLQCSTTHVHKPGNSQQCHLPTLDTGSQNGHPEGGSHPPQRRFQHTSAVILQVQPASPVT-------PQQCAPDDWKEVVPAEKSVPVARPGPSPHQQAIIPAIPGGLPGPKSPNIQQCPAHETGQGIVHALT------------------------------DLSSPGMTSGNGNSAS------------SIAGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLP-EKPPQQDHTTTTDSEMEEPYLQESK--EEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLDLPDMHMRDLVGVGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXK0-1", "uniprot_id": "PHC2_HUMAN", "id": "Q8IXK0-1", "name": "Polyhomeotic-like protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSSACATSSTSGAS---------SSSGCNNSSSGGSG---RPTGPQISVYSGIPDRQTVQVIQQALH------------------------------------------------RQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTP----AAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAG--AKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRT-VPAVAAHPLIAPAYAQLQP---HQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQ--------------------------------------------------------------------------------------------------SRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGP--------------------------VTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPP---------QQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALT------------------------------DLSSPGMTSGNGNSAS------------SIAGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLP-EKLPQQDHTTTTDSEMEEPYLQESK--EEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39769-1", "uniprot_id": "PHP_DROME", "id": "P39769-1", "name": "Polyhomeotic-proximal chromatin protein", "aln": "MDRRALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVISPQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQ--QQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPPSLTPTTNPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLP-KAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKAT------------MQEDIKLSGIASAP-----GSDMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMS-LPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPP--ISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . : :*: . . *:. . : * * :* : .**. . . ::** *:* **: ::* . * : **. ** . : . . * :::: . :*. : .:.:. .*.. :*::* .: . .. * *:::: ::::.*.: ::* : . * *:* * :* : . : : : : : : :. : * : *: * : * *. * *. : : * : . . *: . . : : . . * :: * .. . .: .. . . * ...:::. . .. : .: .**... * :*::**::*****:**:***. ***** * . .. : :.: : . ** ** ::. ::** **:** *::: . . . . . . .: .. . . : *: . *:. . . . . . :.*.*::* :** .****:: .::* ********:****.**:.:*.:******** *::. :*: ", "identical_positions": 115, "similar_positions": 202, "identity": "7.13%" }, { "cls_id": "homologset.agr.HGNC:31830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P63-1", "uniprot_id": "MICU2_RAT", "id": "Q99P63-1", "name": "Calcium uptake protein 2, mitochondrial", "aln": "----MAAAAGRSAWLAAWGGRLRRGLAAGRRAVPTRGPLA----------AAVAGVALAGAGAAWHHGRVKAAAREGSRTVSAQKNYLG---PIEKLSLRKQRFMQFSSLEHDGEYYMTPRDFLFSVMFEQVERKTLVKKLAKKDIEDVLSGIQTARCGST-FFRDLGDKGVISYTEYLFLLTILTKPHSGFHVAFKMLDVDGNEMIERKEFVRLQKIIS--------------------------------------------------------------KQDGFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFVENLQTEVQEMEFLQFSKGLNFMRKEDFAEWLLFFT--NTENKDIYWRNVREKLSVGESISLDEFKSFCHFTTHLEDFAIAMQTFSLAHRPVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRMHRGLWVSQQQSVQEYWKCVKKESIKGVKEAWRQQAGKGPF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CD10-1", "uniprot_id": "MICU2_MOUSE", "id": "Q8CD10-1", "name": "Calcium uptake protein 2, mitochondrial", "aln": "----MAAAAGRSAWLAAWGGRLRRGLAAGRRAVPTRGPLA----------AAVAGVALAGAGAAWHHGRVKAAAREGSRTVSAQKNYLG---PIEKLSLRKQRFMQFSSLEHDGEYYMTPRDFLFSVMFEQVERKTLVKKLAKKDIEDVLSGIQTARCGST-FFRDLGDKGVISYTEYLFLLTILTKPHSGFHVAFKMLDVDGNEMIERKEFVKLQKIIS--------------------------------------------------------------KQDGFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEFLQFSKGLNFMRKEDFAEWLLFFT--NTENKDIYWRNVREKLSVGESISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRMHRGLWVSQQQSVQEYWKCVKKESIKGVKEAWRQQAGKGPF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYU8-1", "uniprot_id": "MICU2_HUMAN", "id": "Q8IYU8-1", "name": "Calcium uptake protein 2, mitochondrial", "aln": "----MAAAAGSCARVAAWGGKLRRGLAVSRQAVRSPGPLA----------AAVAGAALAGAGAAWHHSRVSVAARDGSFTVSAQKNVEHGIIYIGKPSLRKQRFMQFSSLEHEGEYYMTPRDFLFSVMFEQMERKTSVKKLTKKDIEDTLSGIQTAGCGST-FFRDLGDKGLISYTEYLFLLTILTKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIIS--------------------------------------------------------------KQDDLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLFFT--NTENKDIYWKNVREKLSAGESISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRMHRGLWVPQHQSIQEYWKCVKKESIKGVKEVWK-QAGKGLF----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYC5-1", "uniprot_id": "Q1LYC5_DANRE", "id": "Q1LYC5-1", "name": "", "aln": "----MATWARLGATLRSTAKSFWP-----VRSIFYRRAFG----------AGLLGSVVAGG---FIYYKNEPRWRLWPHIVYAEDEKQEQ-IMVPQMSMRRRRFNQFASMIYEDEPYMTPRDFLHSVLMEKVDHKLKKKVLTKADLDEMIKVASKAEAGNN-LFRGIGDKGLISYTEYLFLLTIITKSDTGFHIAFKMLDIDGSETVDKMEFQKLKKVNG--------------------------------------------------------------PKK--ELLRQGGTELSD---NADEVDTTLQVFFFGKDGNKKLQYKDFCRFMEDLQAEVQEVEFTQFSKGMKTMRREDFAEWLLHFT--NEEDNEAYQDNMRKRIPTGQSITFDEFKEFCLFTYHLEDFAISVKMSIEGSKPIGLAQFKRAVMIATGHELSDNVLDTVFKLFDMDGDDCLSHKEFLAVMKDRVHRGLRVQPQYGVSGYWKCVKRETLEGAQEALR-KNGSPI-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHF1-1", "uniprot_id": "A0A0B4KHF1_DROME", "id": "A0A0B4KHF1-1", "name": "", "aln": "MAGLAARLTVKNCTIIAQRSSVIVGVGRSARFSSSSSQMGRIPGHKTRRLLTIVGGSAVSLAALAAFIKLRSAENPVNAVSLKRRMRDDSELENVKLTARERRFIKFASVEYDDQLYMTPQDFLDSVVEQEPRPRLKRRQLSSDEVDKYKENTPALKKGSTRLFRNLRDKGIVSYTEYLFLLSILTKPKSGFRIAFNMFDTDGNQRVDKDEFLVIISILAGALKDTQNVDPQTKRILSRLVSYDEQSQMTKPMAVPQAKRGIMERIFSGAWKEKHGEQEPEEELATPTPLEQNYVNDGEGLQRRHMVATTLQLHFFGKRGTGVINYDNFYRFMDNLQTEVLELEFHEFSKGNSVISELDFAKILLRYTYLATDEYDVFLERLLERVKDEKGISFHDFRDFCHFLNNLDDFTIAMRMYTLADRAISKDEFSRAVKICTGYKLSPHLIDTVFAIFDADGDGLLSYKEFIAIMKDRLHRGFKVSGRFFDYNEALDAYDEPDYPLFVAWRHRVCRHLDYFIDSDALWH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : : . : :. : * .. . : . . : : *.:** :*:*: ::.: ****:*** **: :: : : *:. :::. . *.. :**.: ***::*********:*:**..:**::**:*:* **.: ::: ** : .: . :. . . : . : ****: **** * ::*.:* **:::**:*: *:** :**** . : . ***: ** :* :: : : .: ::: :.*::.:*:.** * :*:**:*::: . :.: :*.*** :.** :** :::**** :** *** **: **:.::*:*:***: * : . *. . : : ", "identical_positions": 111, "similar_positions": 138, "identity": "21.18%" }, { "cls_id": "homologset.agr.HGNC:31834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A704-1", "uniprot_id": "D4A704_RAT", "id": "D4A704-1", "name": "Zinc finger protein 641", "aln": "--------------MLSEQSVAPGAGWEPMSAQLDAAEPGSERGAREEGPWRTAPRPLEHLHSGLEDETLSLQEKAPSAPWVPAVPQEGDTGDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLPQLEGGEEQWVPDPQDVEGRDIRKVTYAGDGGEPKGDTPELETEPSRTLSSMSEETVLWNPGQGPSWRSMPSSSTGTLPRPRFLQEDSVSHLLRSTDTDSLLKPHTCPQCGKQFVWGSHLARHQQTHTGERPYSCLKCEKSFGRRHHLIRHQKTHLHDKPSRCPECGKTFRCSSHLASHQRVHADSKSCKGQEIGESPGAQ---CAPPVPKCHVCTECGKSFGRRHHLVRHWLTHTGEKPFHCPRCEKSFGRKHHLDRHLLTHQGQSPGSSWDRGTSAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ34-1", "uniprot_id": "ZN641_MOUSE", "id": "Q8BZ34-1", "name": "Zinc finger protein 641", "aln": "--------------MLSEQAVGLGTGWEPMNTQLDAAELQSERGTREEGSWRTAPRPLEHLHCGLEDEPLSLQEKATSVPWVPAVPQEGNTGDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLSQQEGGEDQWAPDPQDVEGRDILKVTYTGDGGEPQGDTPELQVEPPRTLSSVTEDTALWNPGQGPSWESMPRNSTGMLLSPRFLQEDTFSRHLHRTDTDSLLKPHTCPQCGKQFVWGSHLARHQQTHTGERPYSCLKCEKSFGRRHHLIRHQKTHLHDKPSRCSECGKSFRCSSHLASHQRVHADSKSCKGQDFGESPAAQH--CVPPVPKCHVCTECGKSFGRRHHLVRHWLTHTGEKPFHCPRCEKSFGRKHHLDRHLLTHQGQSPGSSWDRRTAAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96N77-1", "uniprot_id": "ZN641_HUMAN", "id": "Q96N77-1", "name": "Zinc finger protein 641", "aln": "MQAEDRSQFGSAAEMLSEQTAALGTGWESMNVQLDGAEPQVERGSQEERPWRTVPGPLEHLCCDLEEEPQSLQEKAQSAPWVPAIPQEGNTGDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLSQLEGGEEQWVPDPQDLEERDILRVTYTGDGSEHEGDTPELEAEPPRMLSSVSEDTVLWNPEHDESWDSMPSSSRGMLLGPPFLQEDSFSNLLCSTEMDSLLRPHTCPQCGKQFVWGSHLARHQQTHTGERPYSCLKCEKTFGRRHHLIRHQKTHLHDKTSRCSECGKNFRCNSHLASHQRVHAEGKSCKGQEVGESPGTRKRQRAPPVPKCHVCTECGKSFGRRHHLVRHWLTHTGEKPFQCPRCEKSFGRKHHLDRHLLTHQGQSPRNSWDRGTSVF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:.. *:***.*..***.** ***::** .***.* ***** ..**:*. ****** *.*****:****:*********************************************************************.* ****:**.*****:* *** :***:***.* :******:.**.* ***::*:*.**** :. ** *** .* * * * *****:.*. * *: ****:*************************************:******************.***.****.***.***********:.******:.****.:: .***********************************:************************** .**** *:.*", "identical_positions": 332, "similar_positions": 59, "identity": "75.8%" }, { "cls_id": "homologset.agr.HGNC:31837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N5X7-1", "uniprot_id": "IF4E3_HUMAN", "id": "Q8N5X7-1", "name": "Eukaryotic translation initiation factor 4E type 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPP---------AAAPPAGAREPPGS--------------RAAAAAAAPEPPLGLQQLSALQPEP----------------GGVPLHS--SWT---------------------FWLDRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBB5-1", "uniprot_id": "IF4E3_MOUSE", "id": "Q9DBB5-1", "name": "Eukaryotic translation initiation factor 4E type 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPP---------AAAPP-GANEPLD------------------------------KALSALPPEP----------------GGVPLHS--PWT---------------------FWLDRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEIIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIHQLLPHIAFKAVFYKPHEEHHAFEGGRGKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNP1-1", "uniprot_id": "A0ABZ3NNP1_RAT", "id": "A0ABZ3NNP1-1", "name": "Eukaryotic translation initiation factor 4E type 3", "aln": "RTRGAVRPLLQGARRILVVRATAVQHRREGRGQSQRPGGAHQHRGARPAGQALGIEAVVSDGQVAGDAHAQQQEGRVEAEERGQEGQQLAAQRTRRRPRRGCRAPRSQHDGREAGERAQPVGQAQVEQQVVRRAVQAALPHDEQSEQHVARQAHAQQQAECGQPEAQRGSLGPAAAAARLTSVRHRRRAPPRRPSPLAVGLPGPALRHASSPGPRGCQPAPGRPCPGGSARLGRAAAISVAVRAVGDGHSLRPGRGGLHCRQARSPPHAPRPPPGPPPPPRLLALPPAGPAAAAAAAFATAFAAAAAAAAAAAEPPPLCRSAQRGRRRQSRRGIPRRTGPGWAGGAVATAGRGGRAQDARWRQVAFGPRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEIIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIHQLLPHISFKAVFYKPHEEHHAFEGGRGKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66HY7-1", "uniprot_id": "IF4E3_DANRE", "id": "Q66HY7-1", "name": "Eukaryotic translation initiation factor 4E type 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVPA---------APNLQLNTARQSSP--------------VNSTENDIHIDERELENITNHVEDG----------------TSLPLHS--PWT---------------------FWLDRSLPGTTAAECESNLKKIYTVHTVQSFWSVYNNIPPVSCLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKESTLAVWKELLLATIGEQFTDYCASEDEVVGVSVSVREREDVVQVWNGNASFANEANVLGRIYELLPQISFKAVFYKPHEEHHAFEGGRSRH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . * . . : : .:* :: *: : *****:***** *********:*** ***********:.***********************************:** :**************** .*::**::*******:********* ***:..**.** :*::***:*:*******************.:*", "identical_positions": 140, "similar_positions": 36, "identity": "26.22%" }, { "cls_id": "homologset.agr.HGNC:31839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M4Z8-1", "uniprot_id": "F1M4Z8_RAT", "id": "F1M4Z8-1", "name": "", "aln": "-----------------------------------------------MSSPVPQ----PASSGTQVQPGDL----------------------------------GPCPVAVSPVVPNH----------------------------------------LARGRLES--SFSVEAILARPETREHSATSLPLSTCTSLN-FGSVS-------------------------QYQV--LPWVCSTGTWLPTYLSVGIYPMC----SMSCMPGLNVTHLFCQQGLRLTGSELPSCLGP---LKRAPTVNLQDHNTERHQKRVRTMFSEQQLGELEKVFAKQHNLVGKERAQLAARLHLTENQVRIWFQNRRVKYQKQQKLKSPPP----DAMEEPSNSSEG--------------------------NVRNEDAEAGVGS--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TIS6-1", "uniprot_id": "NOTO_MOUSE", "id": "Q5TIS6-1", "name": "Homeobox protein notochord", "aln": "-----------------------------------------------MSS--------PAPSGTQVQPGSL----------------------------------RPCPGAVSPVVPRR----------------------------------------LARGRLES--SFSVEAILARPKTRELAATSLPLSTCTSLNLLGAVS-------------------------QYGV--LPWVCSTGSWLPAYLSVGVYPLC----SMSCVPGLNVTH--HQQGLRLTGSELPYCLGP---LKWAPTVDLRDHGTERHTKRVRTTFNLQQLQELEKVFAKQHNLVGKERAQLAARLHLTENQVRIWFQNRRVKYQKQQKLKLPSS----SVMEEPSSSSDG--------------------------NIQSEDAELGIGS--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MTQ0-1", "uniprot_id": "NOTO_HUMAN", "id": "A8MTQ0-1", "name": "Homeobox protein notochord", "aln": "-----------------------------------------------MPSPRPRGSPPPAPSGSRVRPPRS----------------------------------GRSPAPRSPTGPNTP---------------------------------------RAPGRFES--PFSVEAILARPDPCAPAASQPSGSACVHPAFWTAAS-------------------------LCATGGLPWACPT-SWLPAYLSVGFYP----------VPGPRVAPVCGLLGFGVTGLELAHCSGLWAFPDWAPTEDLQD--TERQQKRVRTMFNLEQLEELEKVFAKQHNLVGKKRAQLAARLKLTENQVRVWFQNRRVKYQKQQKLRAAVTSAEAASLDEPSSSSIA--------------------------SIQSDDAESGVDG--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEA3-1", "uniprot_id": "Q9VEA3_DROME", "id": "Q9VEA3-1", "name": "Homeobox domain-containing protein", "aln": "MLQNPSKYHANPLSHFLALHNTQASGGGSGGGSSVAGLGGLGGGIHAHGQPHHAALAAAAAAAVAVSAGQSSYQMEHQQQHHQLQQQQQQQQHHHHQQLHTHHQDGHHPHPPTPTTGNNNNNSSSSSNSSSHNSNSNHREQLAAAAATATSHAQLIEAAAAHSSLDVGKSFTIAAILGLQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSNPNNNNNNNNNGGSNSGNNNSSPSVNNFNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLSFQREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGNQVSVSANAAHSVSTERTNGCSAASPSLQEEDNEDSKHSLSLSGALPPLSRAQSESDLSICNDSLDGDSLMDGSEEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*.:. * . * . :*. . * . :: .*:: ***. . . * . : * : : ** * :.. : .: : . . . : : ***** *. :** ** * :*: :** :* ** *:*** **::******:*::*:: : *..* . .::.:* * . . ", "identical_positions": 49, "similar_positions": 60, "identity": "10.32%" }, { "cls_id": "homologset.agr.HGNC:31849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDU0-1", "uniprot_id": "HAP40_RAT", "id": "M0RDU0-1", "name": "40-kDa huntingtin-associated protein", "aln": "MAAGSASSLGGGSWPGSE-----------------AGDFLARYRQVSNKLKKRFLRK-------PNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALAVFTRMQRLAREHGGHPVQQPELPQQLPSVPQPSLPGPQPRPVLGSTLPLPLPPDHAPGSVAQSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYS----WEAFDGHG------QDSSGQLPEELFLLLQSLVMAAHEKDTEGIKKLQVEM---WPLLTAEQNHLLHLVLQETISPSGQGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00558-1", "uniprot_id": "HAP40_MOUSE", "id": "Q00558-1", "name": "40-kDa huntingtin-associated protein", "aln": "MAAGSASSLGGGAWPGSE-----------------AGDFLARYRQVSNKLKKRFLRK-------PNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALALFTRMQRLAREHGGHPVQQLELLPQPPSGPQPPLSGPQPRPVLGSTLPLPQPPDHAPGSVAPSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYS----WEAFDGHG------QDTSGQLPEELFLLLQSLVMAAQEKDTEGIKKLQVEM---WPLLTAEQNHLLHLVLQETISPSGQGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23610-1", "uniprot_id": "HAP40_HUMAN", "id": "P23610-1", "name": "40-kDa huntingtin-associated protein", "aln": "MAAAAAGLGGGGAGPGPE-----------------AGDFLARYRLVSNKLKKRFLRK-------PNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGEAASCQLLARDYTGALAVFTRMQRLAREHGSHPVQS--LPPPPPPAPQP---GPGATPALPAALLPP-----NSGSAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYS----WEAFDSHG------QESSGQLPEELFLLLQSLVMATHEKDTEAIKSLQVEM---WPLLTAEQNHLLHLVLQETISPSGQGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIC9-1", "uniprot_id": "A2BIC9_DANRE", "id": "A2BIC9-1", "name": "", "aln": "MAA--------------------------------EGDFLMRYRAVSNKLKKRFLRK-------PNVAEASEQFGQLAKELKQQDCPQYAAFCNLAMARCEQTLFNAPGEALALTDAARLFLASEQETRA-LRAPG-FDENMQAAMNCYSFAIKVYIEMNQPVMAASLSLELGNALKEMNRPGEAIIHFQRAAELQI-QMPIEALLSLWEMASCKILTRDYDGALAVLSEMQHMCQERG---------------------------------LQLP-------GTNTP----VGAFMDIIAKCEISRVLLLMLLEPPPQKLLPEHAQTLERYA----WESFDSHS------QVN--FLPENVFLLLQSVVMACQEKDTESLKALQTEL---WPLLSAEQNHLLHLVVQERITPFGQGI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXR6-1", "uniprot_id": "Q9VXR6_DROME", "id": "Q9VXR6-1", "name": "", "aln": "MDKLRGGSLGGGGSSSGAPSTAPGHEHHQLEQYQYPKNLIEQYLRASSKIKK-FERAGFFKRFAPSVVDVQADFQRLAYSFEESGIQQYAAMCHIGYAKCESYGGAPQRESEAYLRAARSFLAAHNESGR-LHLRTRHSGFREGAVHCY------HRAADRAVDGCVFKAAILRELKQLQRQLDSTSSFAS---------PTHQIHDLEISAETSGQRGDFRSALQHYDDIVDNVYERRG----------------------------------------------------ARMYGELLRRVEVLRLLLLVHLNLPPARQSPAHIKLIEYYYNLAQFESLPCSADDGGSAERPGAFVPEQQQYALAEITCAWVERKMCDLKHLLRDFGAEFGSLSDMERQLLAVMHAELARSY----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::: :* .*.*:** * * *.*.:. :* :*. .:. . *** *::. *:*:. *: * *** ** . :: * .. :.* . : .:.. .. : : *: : : : * * : * *. . *: .** : *: : ::: : *: *:***: *: ** : * * : :* * :*:: . : :**: * .:. * *:. :* * :: : *: :.:** :: * . ", "identical_positions": 60, "similar_positions": 88, "identity": "14.35%" }, { "cls_id": "homologset.agr.HGNC:3185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AIN6-1", "uniprot_id": "A0A8I6AIN6_RAT", "id": "A0A8I6AIN6-1", "name": "Early endosome antigen 1", "aln": "MDRPRRRGCSDSAPRPRRAGPPSCQLRGRPGRRALAGYLLAGSCSQPLAACGEVGAAKAASTAASSPPSSRLGCRPSRPPVVSNPHWVRRVPAAAAAAAAAAGQTMFRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPLCMKRCVTAIDLSEHYQQVHTELETRGQELLSDSNVTGFICPQCMKSLGSADELFKHYQAVHDAGNDSGHGGEASLALTRDDIALLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKSDGLVTD-SSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEEKGLRAAAEQKATHLTEELSKQTTVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSEHANSEATINQLRSELAKGPQEVAVYVQEIQKLKGSVNELTQKSQTLMEKLQKKDLDYTHLEEKHNEEALSRKNTQAALHQRDLDCQQLQARLTASEGSLQRIQGELREKGEAAQKLKEELREVETKHQHLKVEFKQLQQQREEKEQHGLQLQGEVSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQQQLTQLMEKLKNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKVSAQLDQVTAKFQEKQEHCTQLESHLKDYKEKHLSLEQKAEDLEGQIKKLEANNLEVKASREQAVQSLQQQRQLSTDLELRNAELRKQLQEQKEVVSHTKLDLQNKSEALENIKQTLTKKEEEKVVLKQEFEKLSQDSEAQHKELSDRMQAAITELMVMTAQKDALLAELSTTKGKLSKVSDSLQTSRSEFEKESQKGKAAVLDLEKACKELKHQLQQQTESALKEQSELKKSLEKERETSQQLMIELNSVKGEVTQAQNTLKQKEKEEQQLQGNINQLKQATEQKKKQMEALQGELKNVTSQKAQLESKLQQQAAQAAQELAVEKGKLSALQSTYDKCQADLQQLQSDLYGKESELLATRQDLKCVEEKLALAQEDLISNRNQIGNQNKSIQELQAAKAALEQDLAKKEEVLKEQSKALQDAQREKSVKEKELVTEKSKLAEMEEIKCRQEKEIAKLKEELKSHKQESIKEVTNLKDAKQLLIQQKLELQGKVDSLKAALEQEKERQQLMREQMRKEEEKRKEEFSEKEAKLHSEIKEKEAGVKKHEENEAKLTMQVTTLNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMSCGKCFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDLQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BL66-1", "uniprot_id": "EEA1_MOUSE", "id": "Q8BL66-1", "name": "Early endosome antigen 1", "aln": "---------------------------------------------------------------------------------------------------------MFRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSE------------------------------------------GFICPQCMKSLGSADELFKHYQAVHDAGNDSGHGGEAGLALTRDDITLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKSDGLVTD-SSAELQALEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEEKSLRAAAEQKVTHLTEDLNKQTTVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSEHAHLEATINQLRSELAKGPQEVAVYVQEIQKLKGSINELTQKNQNLTEKLQKKDLDYTHLEEKHNEESASRKTLQASLHQRDLDCQQLQARLTASESSLQRAQGELSEKAEAAQKLREELREVESTRQHLKVEVKQLQQQREEKEQHGLQLQGEVSQLHCKLLETERQLGEAHGRLKEQRQLSSEKLMEKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSATAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKGKESVSLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQQQLTQLTEKLKNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQLTAKFQEKQEHCIQLESHLKDHKEKHLSLEQKVEDLEGHIKKLEADALEVKASKEQALQSLQQQRQLSTDLELRNAELSRELQEQEEVVSCTKLDLQNKSEILENIKQTLTKKEEENVVLKQEFEKLSQDSKTQHKELGDRMQAAVTELTAVKAQKDALLAELSTTKEKLSKVSDSLKNSKSEFEKENQKGKAAVLDLEKACKELKHQLQVQAESALKEQEDLKKSLEKEKETSQQLKIELNSVKGEVSQAQNTLKQKEKDEQQLQGTINQLKQSAEQKKKQIEALQGEVKNAVSQKTVLENKLQQQSSQAAQELAAEKGKLSALQSNYEKCQADLKQLQSDLYGKESELLATRQDLKSVEEKLTLAQEDLISNRNQIGNQNKSIQELQAAKASLEQDSAKKEALLKEQSKALEDAQREKSVKEKELVAEKSKLAEMEEIKCRQEKEITKLNEELKSHKQESIKEITNLKDAKQLLIQQKLELQGRVDSLKAALEQEKESQQLMREQVKKEEEKRKEEFSEKEAKLHSEIKEKEAGMKKHEENEAKLTMQVTTLNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKALELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMSCGKCFSVTVRRHHCRQCGNIFCAECSTKNALTPSSKKPVRVCDACFNDLQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15075-1", "uniprot_id": "EEA1_HUMAN", "id": "Q15075-1", "name": "Early endosome antigen 1", "aln": "---------------------------------------------------------------------------------------------------------MLRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSE------------------------------------------GFICPQCMKSLGSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTD-SSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKKILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDLQG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QS51-1", "uniprot_id": "F1QS51_DANRE", "id": "F1QS51-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MLRRILQMTPGKGGSQ-----SSESEQPSADMNNESSE-------------------------------------------GFICPQCMKSHNSAEELFKHYEVFHEPGDQP-----SPFSPGREDLTLLRQEIQDLQASLKEERWFSEELKKELDKVQGR---IATNKGLQSDGTSGEDAELEMRLNESETEKFNIKQMKDLFEQKAAQLATEIVDIKSRYDEEKSMREALEQRLANLNQDMQKEKQEKEKLSAELLQRPGVEDVEVLKKELVQVQTLMDNMTREREEESERLKGQYEQLQANFTTSEKTIAQLKAELEKGPQEAAVYTQQIHQLQSSLNNLQQQSQALSEKLSRKEKENQELEERLGHEQASKKSLQANLHQKELELQESRARVSSGEAALSRAQAELTERGEEAARLRRELGELEKNQQELKAERKQLQQQREDKENQGLQQQSEISQLHAKLLEAERQVGELQGRLKEQRQLSGEKLKDREQQAADLQLKLSRLEEELKESSTKSTDLQHQLDKSKQQHQELQTLQQSTNGKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKESVSQLETEREDLCAKIQAGEGEAALLNQLQEKNHSLQEQITQLTDKLKNQSESHKQAQDNLHEQVQEQKTHLRSAQDRCQGLETTVTELNTQLTESREKIAQLDTQLKAKTEMLLSAEAAKNAQRADLESHLETAQNALQDKQQELSKVQAQLEEQARRLTEKQEQCSQLENGLKDSRDKLMTAEQRIETLQTQTKKAEVELTELRSGREQAQKEQSSLKKQISELEMKTKELNRLLDSEKQGASTQQEELKKKSSALTETRQKLEKAEQERGALQANLDKLSQEGQKQQAELDKKVQGLSSDLQKTQGEKETLVKEVATVKEALSKASKALKESQTQLDKEKKGSKATLEEKEKVFQKVQQELQKNSEATSKELSNVKGLLEKSIEAEKSLQSQLTALNAQLKQCQDTLKEKEKSEQQLQAELKTRQGSFSQEVKKLKTQVSELQASLAKKTEEEAKQKEQITALSKDLSSEKNRCAELQKTSDGTKESLTALQSDYYGKESELSAVRQDLKVCEEKLVLAQEELVTNRNQLSAYETQIQELKTGHTAMEIDLSKRDEKIKQQVETLQKLQKQQGQTEEQLKKEKAQCEELRESQSALEKDKNKLSADLKTLAEKNEKELKDLQAAKQLLIQQKVEMQGKVEAAQASVEKEQREHQKTRDSIKQNEQQLKAETNKIKQQLASEVKAKEEMVRQREEAEVKMSMQVTALNENVATLKREWQSSQRRVGELEKQTDELRGEIAVLEATVQNNQDERRALLERCVQGEGEMEKLQAKMLEMRRKLDDTTAAMQELGRENQSLQIKQSQSLTRKWTEDHEVQNCMACGKGFSVTVRKHHCRHCGNIFCAECSARNALTPSSKKPVRVCDNCFDELQG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***** ***: *** ** : :.*:*****. ********** .**:******:..*:.*::. : :: *:*::*****:**********:*:********:* ** *. .** :* :*.* ** :*:*::**:*********************.****:****:.:* * **: :.*.:::.*: :.*.:*******:*** ***************** ***.***:**.: ::**::.: * ** **::** *****.***.*::::*:.*:*:* *:.* * *:* :*: : .***: ..* *:*. ** ***::*: *: ::*:::.* :* * : ** *:.* : :*:.** *:*.. *.**.* ********:**::*** *.*:.***.****:***:** :**********.*** ::***.************:***. *:**:*****:*:****** *:****:..********************************.**.:* **.***** *********:*:*********:**:*:*** :************::***:******:***:**** .***:*.**.:**.**:**::*** *:*****:******** ******:.**:***:*********.*: .**:: : :: :***:* ***. **: ::* :: **: * *: : ** *.: *:::.:*** :. .. :: ::**:: ** : *: ::: .* : :*::**. * . :*.* * *:*. *: :::.***: : *: **..::* ::* :*::*: *::*.* ***.*.:*: *:::::**.: .**:: : **. ::::::** : * : ** .::* ***. *:.:.* :*.::: :: *.*:***::**.*****. :: : : .*: *:::: .*:: :*: * * ::* : :::*: ** : : **.. : : : **** **:**** *.***** **** ****:*::****:. :. ****::.::::* * :*:: :::: ::*:. *:::. .*::* **:: *:.* :. **: **. :**: :. **:.:*: *********:*:**:.:: :*::*:*:. :* ::.::::*:: * * : : :* **:* ** ::::** *.*::**:*:****:.*:*:*********.*******:**************************::****:****:* **::****:****:*************::*:*.***:**:******:*** ******:****:**********::*************** **::***", "identical_positions": 754, "similar_positions": 426, "identity": "48.36%" }, { "cls_id": "homologset.agr.HGNC:31850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDU0-1", "uniprot_id": "HAP40_RAT", "id": "M0RDU0-1", "name": "40-kDa huntingtin-associated protein", "aln": "MAAGSASSLGGGSWPGSE-----------------AGDFLARYRQVSNKLKKRFLRK-------PNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALAVFTRMQRLAREHGGHPVQQPELPQQLPSVPQPSLPGPQPRPVLGSTLPLPLPPDHAPGSVAQSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYS----WEAFDGHG------QDSSGQLPEELFLLLQSLVMAAHEKDTEGIKKLQVEM---WPLLTAEQNHLLHLVLQETISPSGQGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00558-1", "uniprot_id": "HAP40_MOUSE", "id": "Q00558-1", "name": "40-kDa huntingtin-associated protein", "aln": "MAAGSASSLGGGAWPGSE-----------------AGDFLARYRQVSNKLKKRFLRK-------PNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALALFTRMQRLAREHGGHPVQQLELLPQPPSGPQPPLSGPQPRPVLGSTLPLPQPPDHAPGSVAPSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYS----WEAFDGHG------QDTSGQLPEELFLLLQSLVMAAQEKDTEGIKKLQVEM---WPLLTAEQNHLLHLVLQETISPSGQGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23610-1", "uniprot_id": "HAP40_HUMAN", "id": "P23610-1", "name": "40-kDa huntingtin-associated protein", "aln": "MAAAAAGLGGGGAGPGPE-----------------AGDFLARYRLVSNKLKKRFLRK-------PNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGEAASCQLLARDYTGALAVFTRMQRLAREHGSHPVQS--LPPPPPPAPQP---GPGATPALPAALLPP-----NSGSAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYS----WEAFDSHG------QESSGQLPEELFLLLQSLVMATHEKDTEAIKSLQVEM---WPLLTAEQNHLLHLVLQETISPSGQGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIC9-1", "uniprot_id": "A2BIC9_DANRE", "id": "A2BIC9-1", "name": "", "aln": "MAA--------------------------------EGDFLMRYRAVSNKLKKRFLRK-------PNVAEASEQFGQLAKELKQQDCPQYAAFCNLAMARCEQTLFNAPGEALALTDAARLFLASEQETRA-LRAPG-FDENMQAAMNCYSFAIKVYIEMNQPVMAASLSLELGNALKEMNRPGEAIIHFQRAAELQI-QMPIEALLSLWEMASCKILTRDYDGALAVLSEMQHMCQERG---------------------------------LQLP-------GTNTP----VGAFMDIIAKCEISRVLLLMLLEPPPQKLLPEHAQTLERYA----WESFDSHS------QVN--FLPENVFLLLQSVVMACQEKDTESLKALQTEL---WPLLSAEQNHLLHLVVQERITPFGQGI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXR6-1", "uniprot_id": "Q9VXR6_DROME", "id": "Q9VXR6-1", "name": "", "aln": "MDKLRGGSLGGGGSSSGAPSTAPGHEHHQLEQYQYPKNLIEQYLRASSKIKK-FERAGFFKRFAPSVVDVQADFQRLAYSFEESGIQQYAAMCHIGYAKCESYGGAPQRESEAYLRAARSFLAAHNESGR-LHLRTRHSGFREGAVHCY------HRAADRAVDGCVFKAAILRELKQLQRQLDSTSSFAS---------PTHQIHDLEISAETSGQRGDFRSALQHYDDIVDNVYERRG----------------------------------------------------ARMYGELLRRVEVLRLLLLVHLNLPPARQSPAHIKLIEYYYNLAQFESLPCSADDGGSAERPGAFVPEQQQYALAEITCAWVERKMCDLKHLLRDFGAEFGSLSDMERQLLAVMHAELARSY----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::: :* .*.*:** * * *.*.:. :* :*. .:. . *** *::. *:*:. *: * *** ** . :: * .. :.* . : .:.. .. : : *: : : : * * : * *. . *: .** : *: : ::: : *: *:***: *: ** : * * : :* * :*:: . : :**: * .:. * *:. :* * :: : *: :.:** :: * . ", "identical_positions": 60, "similar_positions": 88, "identity": "14.35%" }, { "cls_id": "homologset.agr.HGNC:31851", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9QES7-1", "uniprot_id": "A0A8M9QES7_DANRE", "id": "A0A8M9QES7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------MARVIKDERSPDGLVKHTGGCHCGAVRFEVWSAADLHVFNCNCSICTKKQNLHFIVPKSQFTLLQGSDNIITYTFNTHMAKHTFCKTCGVQSFYTPRSNPDGFGVAPHCLDPGTVNSVTVEDFCGQN-WEESMQEHKTIKNMSKPTTQNT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A9A3-1", "uniprot_id": "D4A9A3_RAT", "id": "D4A9A3-1", "name": "Centromere protein V", "aln": "MRRTRSAVATDPREQRRSG---ASGGLSGGESRARRYQSRTRAGGGGGAASSQLSSKPRPK--------PPPRALAAAAEEPPPADTPAASVSAFDLGEQRERWETFQKRQRLSFEGAAKLLLDTFEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNRHFIVPASRFKLLKGAESITTYTFNTHKAQHTFCKRCGVQSFYTPRSNPGGFGIAPHCLDEGTVRSVVTEEFNGSD-WERAIKEHKTIKNMSKE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0U1RR11-1", "uniprot_id": "CENL1_HUMAN", "id": "A0A0U1RR11-1", "name": "Centromere protein V-like protein 1", "aln": "MGRVRNRATAQRRRRKRPGDPPAACAAIAVTGASRAQCPRVQVGVGSHAAAKRWLGRWRRKRRWRRVRKAGPRDLLPSAPTPDPPG-PAPSPKDLDLGAQRERWETFRKLRGLSCEGAAKVLLDTFEYPGLVHHTGGCHCGAVRFAVWAPADLRVVDCSCRLCRKKQHRHFLVPASRFTLLQGAESIVTYRSNTHPALHSFCSRCGVQSFHAAVSDPRVYGVAPHCLDEGTVRSVVIEEVGGGDPGEEAAEEHKAIHKTSSQSAPACPREQEQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::: * . ***:************ **:.***::.:*.* :* ***: **:** *:*.**:*::.* ** *** * *:**. ******::. *:* :*:****** ***.**. *:. * : *.: :***:*:: *. ", "identical_positions": 75, "similar_positions": 41, "identity": "27.47%" }, { "cls_id": "homologset.agr.HGNC:31852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5JQF8-1", "uniprot_id": "PAP1M_HUMAN", "id": "Q5JQF8-1", "name": "Polyadenylate-binding protein 1-like 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETLNFDVIK--GRPVRIMWSQRD--------PSLRKSGVGNVFIKNLGKTIDNKALYN---IFSAFGNILSCKVACDEKGPK-------GYGFVHFQKQESAERAIDVMNGMFLN-YRKIFVGRFKSHKERE----AERGAWARQSTSADVKDFEEDTDEEATLR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZSJ2-1", "uniprot_id": "A0A8I5ZSJ2_RAT", "id": "A0A8I5ZSJ2-1", "name": "", "aln": "-------QPSIRPKTGNPNPQVQHAAR--SLSSSCPER----------GRPRGCALVPQPRLSPPPRCPLAA-------------PQPRSPAAATGGTKETEAFPAARTTDANTPRPQPHAALPPAPRTPASPRPSAAAGCGLRAAETDSALR----------APGRRSPPGLTRSLPAARPERGP-------------GPQPPREPPAGVPAPTGPRRLSAPSVPGKGGR--GSGPAAAVTVASAATVAAEVAAAEAAAAAAAEAAAATVAEAVAEAS--VAEAEAEVEAEVEAEAAAEASLGEAAAAAALAREKAEAGGAAAAVAATEASLAEAS----LEEASLAEAAASPSYGRVDMDEELAAALAAEEEEAAAGGSDDGNPDFP-------------TASLYVGDLHPEVTESMLYEKFSPAGPILSIRLCRDKVTRRSLGYAYVNYQQPVDAKRALETMNFDVIN--GRPVRIMWSQRD--------PSLRKSGVGNVFIKNLGKTIDNKALYN---IFSAFGNILSCKVACDEKGPK-------GYGFVHFQKQESAERAIDALNGMFLN-YRKIFVGRFKSHKERE----AERGAWARQSTSADFKDFDDDSDDEATFR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QB54-1", "uniprot_id": "PABPA_DANRE", "id": "F1QB54-1", "name": "Polyadenylate-binding protein 1A", "aln": "MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMMTRRSLGYAYVNFQQPADAERALDTMNFDVIKGRPVRIMWSQRDPSLRKSGVGNIFIKNLDKSID-NKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETHEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAEMGARAKEFTNVYIKNFGEDMDDEKLKEIFCKYGP-ALSIRVMTDDSGKSKGFGFVSFERHEDAQRAVDEMNGKEMNGKQVYVGRAQKKGERQTELKRKFEQMKQDRMTRYQGVNLYVKNLDDGLDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTSQYMQRMASVRAVPNPVLNPYQPAPPSGYFMAAIPQAQNRAAYYPTSQLAQLRPSPRWATQGVRPQHFQNMPNAAVRPSAPRPQTFNPVRPASQVPRMMTSQRMGSQAMGPRPAAAGAATGPAQVRGVPQYKYAPGVRNPQQHMPTQPQVPMQQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQNMHPS-LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKSVPSPAVPAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W158-1", "uniprot_id": "Q9W158_DROME", "id": "Q9W158-1", "name": "RRM domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFVNSMTFRGNP---ANYHQQQPALNHHTLAAAHHQQQLHHHAAAAGHLSHVG----------------------GGHAASNHLAAAAVLGRHGHNSLGSGHTSTSSHSANVGVGVGG-----------------------------GALASGSTGGSGGNSSPD------------------SGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGN-SRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRD-------REQEKATHFKNLYVKNLSEEFTEQHLRE---MFEPYGRITSHKLMLDEEGRSR------RFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQ------------QEINRKLEERKRQKAGQIFYY----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . : . . . . : : . * . . . : .:* : ::.: : : : : . .: : . :* . . :: . . ::. . .. . : : .. . . . . : ", "identical_positions": 3, "similar_positions": 56, "identity": "0.47%" }, { "cls_id": "homologset.agr.HGNC:31853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DHV7-1", "uniprot_id": "ADAL_HUMAN", "id": "Q6DHV7-1", "name": "N6-Methyl-AMP deaminase", "aln": "------------------MIEAEEQQPCKTDFYSELPKVELHAHLNGSISSHTMKKLIAQKPDLKIHDQMTVIDKGK-----------------------------------------------------------KRTLEECFQMFQTIHQLTSSPEDILMVTKDVIKEFADDGVKYLELRST---PRRENATGMTKKTYVESILEGIK--------------------QSKQENLDIDVRYLIAVDRRG-------GPLVAKETVKLAEEFFLSTEGTVLGLDLSG----DP-----------TVGQAKDFLEPLLEAKKAGLKLALHLSEIPNQKKETQILLDLL---PDRIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPS---YDQHHFGFWYSIAHPSVICTDDKGVFATHLSQEYQLAAETFNLTQSQVWDLSYESINYIFASDSTRSELRKKWNHLKPRVLHI-------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80SY6-1", "uniprot_id": "ADAL_MOUSE", "id": "Q80SY6-1", "name": "N6-Methyl-AMP deaminase", "aln": "-------------------MEAGQQWPGKTDFYLQLPKVELHAHLNGSISSSTMKKLIAKKPHLNVHGHMTMIDKGK-----------------------------------------------------------KRTLQECFQMFQVIHQLTTSAEDILMVTKDVIKEFADDGVKYLELRST---PREENATGMTRKTYVESVLEGIK--------------------QCKQENLDIDVRYLMAIDRRG-------GPTIARETVELAKEFFLSTENTVLGLDLSG----DP-----------TIGQANDFLEPLLEAKKAGLKLALHLAEIPNREKENQMLLSLL---PDRIGHGTFLSASEAGALDQVDFVRQHQIPLELCLTSNIKSQTVPS---YDQHHFGFWYSIAHPSVICTDDKGVFATYLSQEYQLAAETFNLTPFQVWDLSYESINYIFACDNTRSELRKRWTHLKQKVLNCNEVNYF-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V9P6-1", "uniprot_id": "ADAL_DANRE", "id": "Q4V9P6-1", "name": "N6-Methyl-AMP deaminase", "aln": "-------------------MDTEADL-----FYRQLPKVELHAHLNGSVSFETMEKLIKRKPHLNIEHSMTAIRRGQ-----------------------------------------------------------RRTLDECFQVFKVIHQLVDSEEDILMVAKSVIQEFAADGVKYLELRST---PREVTETGLSKQRYIETVLEAIR--------------------QCKQEGVDIDVRFLVAVDRRH-------GPEVAMQTVKLAEDFLLSSDGTVVGLDLSG----DP-----------TVGHGKDLLAALQKAKNCGLKLALHLSEVPSQIDETELLLNLP---PDRIGHGTFLHPDVGGSDSLVDKVCKQNIPIEICLTSNVKGQTVPS---YDKHHFKYWYNRGHPCVLCTDDKGVFCTDLSQEYQLAASTFGLTKEAVWILSQQAIGYTFAPEPIKQRLEKTWAELKQQILQ--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHH7-1", "uniprot_id": "ADAL_DROME", "id": "Q9VHH7-1", "name": "Adenosine deaminase-like protein", "aln": "-------------------MEQ---------FLKGLPKVELHAHLNGSLGIKSLCDLGERLYGTSCKDFLKLCAHFSR---------------------------------------------------------FEKDMDACFEKFAFVHELTSTREGLRFATELAIRDFAEDNVQYVEMRTT---PKAN--ENYSRRDYLQIVIDAIK--------------------AASETYPEITVKLLPSINRAE-------PVDVAEETVSLAVELARAHPNLILGIDLSG----NP-----------GKGRFSDFAPILAQARDKGLKLAIHCAEIENP-SEVKEMLHFG---MSRCGHGTFLTPEDIG------QLKQRNIAIECCLTSNVKSGTVPS---LEEHHLKRIMEADAPKVICTDDSGVFDTTLTKEFLIAAETFGLTREQCIDLTLEAVHHSFASEQEQIQMADRVGNYADILVK--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I5ZWX3-1", "uniprot_id": "A0A8I5ZWX3_RAT", "id": "A0A8I5ZWX3-1", "name": "", "aln": "MGNSHSTPLLSALQELLGQRKLKIEKKILLSFLDECNRCAPWFIVSGSLTLRAWDKLGKDLDREITEGKLKPGTKPLWRMVRACLEDKRCEEAVRTGQKILTEQQESMSEGEKVSKGEKKRKGDKRNREKAEMKKGDNQDQETNKIYPSLKALTLGMSSDSELSDNDLADLEEEAARYEKERYYRDWPHANAMWQQAKEVDKEAVIPTAPPAPPYNSQHKRMVKPAGGTSFCPEVWKEIGLSFPVFLDANGQRYHEPVDSKTIKQLAKSVKTYGVNTAFVIAQIEALGRYCLTPGDWGSLARACLSPGQYLDWKSYLYEYANIQAAINLASGADPQRHWDADMLLGIGRFALDQIGYPDQVYSQINEIAIKAWKALPNRGAVSGNLTKVLQGSTEPFSDFVARMVESAIKVFGDPDTAMPLIKQLVYEQCTKECRTAITPYKHKGLEIWMKVCREIGGPLTNVGLAAAMIQLRKKVTAETCFKCGRKGHYRRQCPERSGERGSNRPPQPRLCPRCRKGNHWASECRSVKDLDGRPLATGYGGTQPKNGQRGPRPQGPQIYGALQKDRQGQEKQRPWPSLHHPKDQGEPLKAPQNWTSTPPPDSY", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : :.**: : .* . :. : . : : : :: *. .. :. : :: : .:* : * *: ::. : :: . : :* : :: : .. . : :: * * *: * * : . : : . . : . :* : .: *: : . .. .:. **. ::. * * . * . . . :. ::* * .: . . : :: : . . ", "identical_positions": 23, "similar_positions": 92, "identity": "3.81%" }, { "cls_id": "homologset.agr.HGNC:31855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10631-1", "uniprot_id": "PYY_RAT", "id": "P10631-1", "name": "Peptide YY", "aln": "MVAVRRPWPVMVAMLLVLLACLGALVDAYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRYGKREVPAALFSKLLFTDDS--ENLPFRSRPEGVDQW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPS2-1", "uniprot_id": "PYY_MOUSE", "id": "Q9EPS2-1", "name": "Peptide YY", "aln": "MVAVRRPWPVTVAMLLILLACLGALVDAYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRYGKRDVPAALFSKLLFTDDSDSENLPFR--PEGLDQW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JQD4-1", "uniprot_id": "PYY3_HUMAN", "id": "Q5JQD4-1", "name": "Putative peptide YY-3", "aln": "MVSVCRPWPAVAIALLALLVCLGALVDTCPIKPEAPGEDESLEELSHYYASLCHYLNVVTRQWW------------------------------EGADMW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8P2-1", "uniprot_id": "PYYA_DANRE", "id": "Q9I8P2-1", "name": "Peptide YY-A", "aln": "MAVMLKPWTVVATVLICVLLCLGTFVDAYPPKPENPGDDAAPEELAKYYTALRHYINLITRQRYGKRSTSEDVMAELLFGDDT---EHKQRSRYDDSFMW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :**.. . *: :* ***::**: * *** **:* : ***::**::* **:*::*** : :. *", "identical_positions": 30, "similar_positions": 23, "identity": "30.0%" }, { "cls_id": "homologset.agr.HGNC:31859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTX1-1", "uniprot_id": "D3ZTX1_RAT", "id": "D3ZTX1-1", "name": "Tripartite motif-containing protein 67", "aln": "MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPPPLLLSRGA---AAAAAAPPPDQDAAAGATCGGAGASTAGGLGGGAAGGGDHADKLSLYSETDSGYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACS------------SLCSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEGIVQRYQQGRGVAAGASAAPAVAICQLCDRTPPEPAATLCEQCDVLYCATCQLKCHPSRGPFAKHRLVQPPPPPAPP-EATSASVGTSTASSAGG--CRSPGGAGAPVP-----RKFPTCPEHEMENYSMYCVSCRSPVCYMCLEEGRHGKHEVKPLGATWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREQKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKEDDPSGFLQISDALIKRVQTSQEQWVKGAL--EPKVSAEFDLTLDSEPLLQAIHQLDFVQMKCR---------VPPVPLLQLEKCCTRNNSATLAWRTPPFTHSPADGYILELDDGDGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSG---HRDIILSNDNQTATCSSYDDRVVLGTAAFSKGAHYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLEVPTNLGRPKLSGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q505D9-1", "uniprot_id": "TRI67_MOUSE", "id": "Q505D9-1", "name": "Tripartite motif-containing protein 67", "aln": "MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPPPLLLSRG-----AAAAATPPDQDAAAGATSGGAGANTAGGLGGGATGGGDHADKLSLYSETDSGYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACS------------SLCSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEGIVQRYQQGRGVVPGAAAAPAVAICQLCDRTPPEPAATLCEQCDVLYCATCQLKCHPSRGPFAKHRLVQPPPPPTPP-EATPAVTGTSTASSAGG--CRSPGGAGASAP-----RKFPTCPEHEMENYSMYCVSCRSPVCYMCLEEGRHSKHEVKPLGATWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKEDDPSGFLQISDALIKRVQTSQEQWVKGAL--EPKVSAEFDLTLDSEPLLQAIHQLDFVQMK-----------LPPVPLLQLEKCCTRNNSVTLAWRTPPFTHSPAEGYILELDDGDGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSG---HRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLEVPTNLGRPKLSGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZTA4-3", "uniprot_id": "TRI67_HUMAN", "id": "Q6ZTA4-3", "name": "Tripartite motif-containing protein 67", "aln": "MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAGAAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACS------------SLSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGAL--EPKVSAEFDLTLDSEPLLQAIHQLDFIQMKCR---------VPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSG---HRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLEVPTNLGRPKLSGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9MRI4-1", "uniprot_id": "TRIM9_DROME", "id": "M9MRI4-1", "name": "E3 ubiquitin-protein ligase TRIM9", "aln": "MEDELRCPTCKQLYANPVLLPCFHALCLGCA--LDIQTPYSPGSALPGAVNGAG-----AASAAGHNGLHGNGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGS--ESVTSDQDQSDKVSIFSEADSGVVCCSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRF-----------CAREALRCQMCETDP-KVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKP--------------RGAAQQ-------------------------RESVCGEHEET-LSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFIQRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDDAALARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQPP--NHSFVEGYVLELDDGSGGEFREVYCGKETICTVDGLHFNSMYNARVKAFNSAGEGEYSELIGLQTAEVAWFTFDPVLSGGAGSGLIFSKNNATVSVEGWEHRVALGSVGFSRGVHYWEFTIDNYTADTDPAFGVARIDVARNKMLGKDEKSFAMYIDRQRSWFQHNSIHERRVEGGITTGSTIGVLLDLERHTLSFLVNEMPQGSVAFRDLYGVFYPAVSINRGVTLTMHTAMDAP------KMDYF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 294, "similar_positions": 253, "identity": "36.34%" }, { "cls_id": "homologset.agr.HGNC:31860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PV82-1", "uniprot_id": "FA53A_MOUSE", "id": "E9PV82-1", "name": "Protein FAM53A", "aln": "MVTLITEKLQNQSLDDLTRRACEAGP--YSAEKLNKSGHLFPLEISVDKSPWKALRGGWPTGSQAASGP---FSVGPHGVSHTEGLKWQLESPGP---MDVGHFLDLHDSTGPPAAPPTKRHCRSLSEPEELARCRSPWRPGSSKVWTPISKRRCNSGGSATLQCCSGVGNPTLQGTLVPGLPRRPVSPAGPTSPLTPRPASASSGFVDGSEGSTSSGPPWLSTGPCPFSSRRRLSLSQEHLVDTGACLPSASSTPTSTPELGRHHGLLRCRSQPCVLDGRRVRRKRRREEDARWTRPSLDFLKMTRTLKNSKSLCSLDYEDD-EDDTQEKTLVSSPCNSQGLVGIITPSSSPRIPRPGPDSPSIWASGEPEANPGEGGSSGDPSDWDSAGEEGIFPLDHGDLDLEQIENN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NSI3-1", "uniprot_id": "FA53A_HUMAN", "id": "Q6NSI3-1", "name": "Protein FAM53A", "aln": "MVTLITEKLQSQSLDDLTCKA-EAGPLQYSAETLNKSGRLFPLELN-DQSPWKVFSGGPPVRSQAATGPDFSFLPGLSAAAHTMGLQWQPQSPRPGAGLGAASTVDPSESTGSSTAPPTKRHCRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGGSATRQGSPGA-----------VLPRSAVWSTGPTSPATPRPSSASGGFVDSSEGSAGSGPLWCSAESCLPSTRRRPSLSQERLAGAGTPLPWASSSPTSTPALGGRRGLLRCRSQPCVLSGKRSRRKRRREEDARWTRPSLDFLKMTQTLKNSKSLCSLNYEDDDEDDTPVKTVLSSPCDSRGLPGITMPGCSQRGLRTSPVHPNLWASRESVTSDGSRRSSGDPRDGDSVGEEGVFPRARWELDLEQIENN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********.******* :* **** ****.*****:*****:. *:****.: ** *. ****:** * * ..:** **:** :** * :... :* :***..:*****************.****************:*****:****** * ..*. *** .* .:***** ****:***.****.****:.*** * *: .* *:*** *****:*..:*: ** ***:***** ** ::************.*:* ***********************:***********:**** **** **::****:*:** ** *..* * *..* *.:*** *. :. *. ***** * **.****:** : :*********", "identical_positions": 265, "similar_positions": 72, "identity": "64.48%" }, { "cls_id": "homologset.agr.HGNC:31865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3YZG8-1", "uniprot_id": "MTD2L_MOUSE", "id": "D3YZG8-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MATRARGFSLLRGRLGRGP---------VRAPGVAERAWRG-FGSSGRRHEAVIISGTNMAKQIQKEIQQGVESWIALGNRR-PHLSIILVGDNPASHTYVRNKIKAASAVGICSELIIKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRAGIET---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPREQLKAHTQLADIIIVAAGIPRLITADMVREGAAVIDVGIN--YIQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNIAY------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUA0-1", "uniprot_id": "MTD2L_RAT", "id": "D3ZUA0-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MATRARGLSLLRGRLGRGP---------ARAPGVAERAWRG-FGSSSRRHEAVIISGTEMAKQIRRELQQGVESWLALGNRR-PHLSIILVGDNPASHTYVRNKIRAASAVGICSELIVKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRAGIET---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRHTPREQLKAHTQLAEIIIVAAGIPGLITADMVREGATVIDVGIN--YVQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNITY------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H903-4", "uniprot_id": "MTD2L_HUMAN", "id": "Q9H903-4", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSAFRG-FRSSGVRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRR-PHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRTGIQT---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGIN--YVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEG5-1", "uniprot_id": "A0A8M2BEG5_DANRE", "id": "A0A8M2BEG5-1", "name": "methenyltetrahydrofolate cyclohydrolase", "aln": "MAAPG-ALTVNYTRIQTLMSCFTYCRRPKRWINLKTVNRRSSFCQSLKRHVATVVSGAELARQIHKEVQSDIAKLVAEGNRR-PHLSVILVGDDHASHTYVRNKTRTASLLGMSSSTIFRPSSVSQEEMLELIDKFNRDRNISGLLVQLPLPEHINERAICNAVAPEKDVDGFHIVNIGKLCLDQ---------RCMIPATAAAVWEIIRRTGLET---------VGKNVLVVGRSKNVGMPIAMLLHSDRKHERSGGDATVIMAHRCTPLPRLKELARLADIVIAAAGVPHLITADMVKEGAAVIDVGIN--RMQDPVTGKSRLVGDVDFEAVKEKAGFITPVPGGVGPMTIAMLQANTLVTEEKKIVEWAETRLCLLLASGSGSDAGHYTGMAKKDWIHWSSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04448-1", "uniprot_id": "MTDC_DROME", "id": "Q04448-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "aln": "--------------------------------------------MRFTSNMAQIIDGKAIAQEVRTQLAHELKGMEAAGYPK-PHLTAVIVGEDPASEKYVANKMVACREVGISSETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGRTALDM---------EANIPATPLGVKRLLEHMKIET---------LGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVTICHRYTPPKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGIN--RIKDESTGQFKLVGDVDFEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAARKQFDDRKSS-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02046-1", "uniprot_id": "MTD1_YEAST", "id": "Q02046-1", "name": "Methylenetetrahydrofolate dehydrogenase [NAD(+)]", "aln": "-----------------------------------------------MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVIE---DKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTG---KVTIAMLLRNMLRLVRNVELSKEK--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :*. .. :: : : * * .:..:: *:. *. . :. :*: . :: : : . * * :.*::* :*: : ::: : : : :***:*:: : . : .. :*.*. .: .::. : . *:: :* .**: *. *:* ** * .: * . . : *:* *. : : ::: . . : *:: *. .*:.* :*:*** * * .: ", "identical_positions": 41, "similar_positions": 97, "identity": "10.12%" }, { "cls_id": "homologset.agr.HGNC:3188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8YPE2-1", "uniprot_id": "A0A8J8YPE2_RAT", "id": "A0A8J8YPE2-1", "name": "Polycomb protein EED", "aln": "VAGSHARPPRRLGAICDSGGSGGGGGAGSFAAGSGRACLTAVWRRPRPRRQEPGGRRRNMSEREVSTAP---AGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGE------IRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75530-1", "uniprot_id": "EED_HUMAN", "id": "O75530-1", "name": "Polycomb protein EED", "aln": "-----------------------------------------------------------MSEREVSTAP---AGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGE------IRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q921E6-1", "uniprot_id": "EED_MOUSE", "id": "Q921E6-1", "name": "Polycomb protein EED", "aln": "-----------------------------------------------------------MSEREVSTAP---AGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGE------IRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q566T0-1", "uniprot_id": "EED_DANRE", "id": "Q566T0-1", "name": "Polycomb protein eed", "aln": "-----------------------------------------------------------MKMRRKMSEPHGEAGNEMPN-KKQKLSSDENSNPDLSGDDNDDAVSVESGTHPERPDTPTNTASAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHGQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGE------IRLLQSYVDADADENFYTCAWTFDCSSSHPLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADFDLLGEKIMSCGMDHSLKLWRLDSERLQRAIRGSYEYNPSKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGRMEDDIDRIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTLPRCTSAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24338-1", "uniprot_id": "ESC_DROME", "id": "Q24338-1", "name": "Polycomb protein esc", "aln": "----------------------------------------------------------------------------MSSDKVKNGNEPEESEES----CGDESASYTTNSTTSRSKSPSSSTRSKRRG--RRSTKSKPKSRAAYKYDTHVKENHGANIFGVAFNTLLGKDEPQVFATAGSNRVTVYECPRQGG------MQLLHCYADPDPDEVFYTCAWSYDLKTSSPLLAAAGYRGVIRVIDVEQNEAVGNYIGHGQAINELKFHPHKLQLLLSGSKDHAIRLWNIQSHVCIAILGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLNTPEFHHKIELSNTFSQEKSTLPFPTVTKHFPDFSTRDIHRNYVDCVQWFGNFVLSKSCENAIVCWKPGQLHQSFEQVKPSDSSCTIIAEFEYDECEIWFVRFGFNPWQKVIALGNQQGKVYVWELDPSDPEGAHMTTLHNSRSVATVRQIAFSRDASVLVYVCDDATVWRWNRRQTTSI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKD5-1", "uniprot_id": "Q9VKD5_DROME", "id": "Q9VKD5-1", "name": "Polycomb protein esc", "aln": "-------------------------------------------MTETNPSEISPPSEEPPAEDESTDHSPAEAVLSNNSSSVCNVVEPDDEHEVNSVDREDTASLFSTTTTTTRSKSPN--TRKLNRL--CRRIKAPKMVQPLYKYSSHVREDHNHQIFGVQFNPFLDRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSYDSVTGDPVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNIQSDVCVAVFGGVEGHRDEVLSVDFDLRGDRIMSSGMDHSLKLWRLDKPDIKEAIELSSGFSPNKNTGPFPTIKEHFPDFSTRDIHRNYVDCVQWFGDFVFSKSCENSIVCWKPGKLSESWHEIKPQESATTVLHHFDYKMCEIWFVRFAFNAWQKILALGNQLGTTFVWELDCNDPNLTKCSQLVHPKSNSTIRQTSFSKDGSILVCVCDDSTVWRWDRVN----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . ::.. * : : : . *..:*. . * : : :* . ::*:*. :*** ** ..:* ****.*.:**::*** . ::**: *.*.*.** ******::* :. *:**.** **:**::: :. :*:***:********* :**** ****::******:.. :*::************ *::: *::*:*.********* ::. : . *. * :. .*.. ** : . ******************:*:*::::******:*******:: :. ..:**.:* *:: .*:*. *:**::**.:: ***::***** *. :**:*: .**. :: : * :. :::** :**:*.*:*: ****:::***:* . ", "identical_positions": 178, "similar_positions": 137, "identity": "34.7%" }, { "cls_id": "homologset.agr.HGNC:31884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O97066-1", "uniprot_id": "O97066_DROME", "id": "O97066-1", "name": "Signal peptidase complex catalytic subunit SEC11", "aln": "MGVASMLQIDEMLGDFNRMNKRQSLYQVLSFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYKEEPVRVGEIVVFKVEGRDIPIVHRVIKLHEKEDGSVKFLTKGDNNNVDDRGLYAPNQLWLTK-KDIVGRARGFLPYVGIITIFMNEYPKVKWAILSILAIFVLLHRE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C7V7-1", "uniprot_id": "SC11B_HUMAN", "id": "P0C7V7-1", "name": "Putative signal peptidase complex catalytic subunit SEC11B", "aln": "------------------MNKWRLYYQVLNFGMIVSSALMIWKGLMVITGSESP-IVLLSGSMEPAFHRGYLLFLTNRVEDPIRVGEIAVLRIEGRKIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQDQHWLEK-KDVVGRARGFVPYIGIGTSLMNDYPKHKYEVLFLLGLFVLVHRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15367-1", "uniprot_id": "SEC11_YEAST", "id": "P15367-1", "name": "Signal peptidase complex catalytic subunit SEC11", "aln": "------------------MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNR-NTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ::*.. ::.:** *:*:** : *.* ** :*:*********:** :*** * : :**::.* .:**:.*******:: *::. . :******* :* .** .: :* * *::** .:*:.* :* * :.: *: :* :*.: .*: *", "identical_positions": 66, "similar_positions": 54, "identity": "35.48%" }, { "cls_id": "homologset.agr.HGNC:31886", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C672-1", "uniprot_id": "TSN19_HUMAN", "id": "P0C672-1", "name": "Tetraspanin-19", "aln": "---------MLRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDR------------NNFLTAFDENNHFIVPISQILIGMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTD-----------------------WIKNKNKENSGQVPCSCTKSTLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNIKNIIHAEM-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24188-1", "uniprot_id": "LBM_DROME", "id": "Q24188-1", "name": "Protein late bloomer", "aln": "-----------MGCATTSVKIASIVLN---AVLGFLAAGAIGWIAYN------------------ADTETEEFVIAAYIACS----LILVFALLGIFAAIRESVVLTATSAVFLLILAILQIVSTCLFLHEFD-----VKSGRDMVEVAWQANN----------MDSLQQKHECCGQSSAQD-----------------------YIH-----LSLLIPPSCYAD------LQQTPDHLYLDGCIEKVQSFYESDKLRFIIVSWVLVAFELICFALAVFLAISFKNKQRRMEF------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQK9-1", "uniprot_id": "Q8IQK9_DROME", "id": "Q8IQK9-1", "name": "", "aln": "------------MACCFNYKFVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLFYIALGVAIAG--FVATLAAVVGFWASCLHTYCFLTIYFLSVVVLLLTESVL-CLAITLWPHCLGISLDETQMVRSLQSNYGVPGQEQFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGYGQRNWPVPLSCCFLKNAGHSMAYLDPKPANESMCQSLERLSYERERHTESCLPHLDNWYREQYSIFLGASLILAMIEFCVLLAIIMSCTGLASQRARLKKPVQEMRTQKVKSRQTLIENIYEPDVELRENSNHSGDGIYLGPASRHVSSEDFKELYIKPRDLYKQHNLRTSPANRPTQMRNYLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O46101-1", "uniprot_id": "TSN2A_DROME", "id": "O46101-1", "name": "Tetraspanin-2A", "aln": "MGIGYGASDEQLEKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPG-----------FNDWLRILEAQSFYIGVYVLIGIS-IVMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTIN---SSLQPLLNVSLRGFVATSEYTYSNYVLTMIQENIGCCGATGPWD-----------------------YLD-----LRQPLPSSCRDT---------VSGNAFFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVKKEEEQASNYRR---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : . :: : : * : ..:* . . . .. : : : * *** . * ::. * .. . :.* .: ::. . :: * :. . . . ", "identical_positions": 12, "similar_positions": 40, "identity": "3.18%" }, { "cls_id": "homologset.agr.HGNC:3189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10126-1", "uniprot_id": "EF1A1_MOUSE", "id": "P10126-1", "name": "Elongation factor 1-alpha 1", "aln": "MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62630-1", "uniprot_id": "EF1A1_RAT", "id": "P62630-1", "name": "Elongation factor 1-alpha 1", "aln": "MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68104-1", "uniprot_id": "EF1A1_HUMAN", "id": "P68104-1", "name": "Elongation factor 1-alpha 1", "aln": "MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05303-1", "uniprot_id": "EF1A2_DROME", "id": "P05303-1", "name": "Elongation factor 1-alpha 2", "aln": "MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYEEIKKEVSSYIKKIGYNPASVAFVPISGWHGDNMLEPSEKMPWFKGWSVERKEGKAEGKCLIDALDAILPPQRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGLLKPGMVVNFAPVNLVTEVKSVEMHHEALTEAMPGDNVGFNVKNVSVKELRRGYVAGDSKNNPPRGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFSEIKEKCDRRTGKTTETEPKAIKSGDAAIIVLVPSKPLCVESFQEFPPLGRFAVRDMRQTVAVGVIKSVNFKETTSGKVTKAAEKAQKKK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08736-1", "uniprot_id": "EF1A1_DROME", "id": "P08736-1", "name": "Elongation factor 1-alpha 1", "aln": "MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYNPAAVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGNADGKTLIDALDAILPPARPTDKALRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPPKGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFAEIKEKVDRRSGKTTEENPKFIKSGDAAIVNLVPSKPLCVEAFQEFPPLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAAEKATKGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02994-1", "uniprot_id": "EF1A_YEAST", "id": "P02994-1", "name": "Elongation factor 1-alpha", "aln": "MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVK--WDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDKTEK-AAKVTKAAQKAAKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***:************************************ *:**************************:******.** **:***********************:**:*.*.*********:**********:****:****.****** : :.: *::** **.*.:***:**** :*.*******:****:*.: : **:***. * * ..*. *::*:*.* * *****.*************************::*** ** ***..:.*********** * :.:***************::*** *.**:* :** .*.*.* **:*******: **:************:* *: ** ***:**. * ** :******:: :**.**:***:*.::*********************:*: . ..****:*:** * ", "identical_positions": 336, "similar_positions": 81, "identity": "72.57%" }, { "cls_id": "homologset.agr.HGNC:31894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PZF7-1", "uniprot_id": "E9PZF7_MOUSE", "id": "E9PZF7-1", "name": "", "aln": "MEEQDNTAGKKLQHQTRAEAPGTKSWQSQAYTLGAISNFMSTFLTFPIYKVVFRQQIHAVALSEAVKQLWHEGPQYFYRGIYPPLLSKTLQGTLLFGTYDSLLCFLSPVGPHSLGQRWTAGLMSGVVEAVALSPFERVQNVLQDARKQACFPSTFSILKEFNSYGLWGRLSLGYYRGFWPVLVRNSLGSALYFSFKDPIQDGLARQGLPHWVPALVSGSVNGTITCLILYPLMVLVANMQSHIGWQRMPSLWASAQDVWDTRGRKILLIYRGGSLIVLRSSVTWGLTTAIHDFLQRKAHTKKEMTD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5H9E4-1", "uniprot_id": "S2553_HUMAN", "id": "Q5H9E4-1", "name": "Solute carrier family 25 member 53", "aln": "MGEQNHSPGKELQHRTRAEAPGKKSWHSQAYALGAVSNFMSTFLTFPIYKVVFRQQIHAMAVSEAVRQLWHEGPQYFYRGIYPPLLSKTLQGTLLFGTYDSLLCFLSPVGPHTLGHRWAAGLMSGVVEAVALSPFERVQNVLQDGRKQARFPSTFSILKEFNSYGLWGRLSLGYYRGFWPVLARNSLGSALYFSFKDPIQDGLAEQGLPHWVPALVSGSVNGTITCLVLYPLIVLVANMQSHIGWQNMPSLWASAQDVWNTRGRKLLLIYRGGSLVILRSSVTWGLTTAIHDFLQRKSHSRKELKTD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **:::.**:***:*******.***:****:***:***********************:*:****:*********************************************:**:**:*************************.**** ********************************.*********************.**********************:****:*************.************:*****:*********::********************:*::**:. ", "identical_positions": 272, "similar_positions": 31, "identity": "88.6%" }, { "cls_id": "homologset.agr.HGNC:319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61282-1", "uniprot_id": "PGCA_MOUSE", "id": "Q61282-1", "name": "Aggrecan core protein", "aln": "-MTTLLLVFVTLRVIAAVISEEVPDHD--NSLSVSIPQPSPLKVLLGSSLTIPCYFIDPMHPVTT---APSTAPLTPRIKWSRVSKEKEVVLLVATEGQVRVNSIYQDKVSLPNYPAIPSDATLEIQNLRSNDSGIYRCEVMHGIEDSEATLEVIVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQGGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYLHANQTGYPDPSSRYDAICYTGED-----FVDIPENFFGVGGEDDITIQTVTWPDLELPLPRNVTEGEALGSVILTAKPIFDLSPTISEPGEALTLAPEVGSTAFPEAEERTGEATRPWGFPAEVTRGPDSATAFASEDLVVRVTISPGAAEVPGQPRLPGGVVFHYR-PGSTRYSLTFEEAQQACMHTGAVIASPEQLQAAYEAGYEQCDAGWLQDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSSETYDVYCYVDKLEGEVFFATRLEQFTFQEARAFCAAQNATLASTGQLYAAWSQGLDKCYAGWLADGTLRYPIITPRPACGGDKPGVRTVYLYPNQTGLPDPLSKHHAFCFRGVSVAPSPGEEGGSTPTSPSDIEDWIVTQVGPGVDAVPLEPKTTEVP--------YFTTEPRKQTEWEPAYTPVGTSPQPGIPPTWLPTLPAAEEHTESPSASEEPSASAVP------------------------------------------------STSEEPYTSSFAVPSMTELPGSGEASGAPDLSGDFTGSGDASGRLDSSGQPSGGIESGLPSGDLDSSGLSPTVSSGLPVESGSASGDGE-VPWSHTPTVGRLPSGGESPEGSAS-----------------ASGTGDLSGLPSG------------------GEITETSTSGAEETSGLPSG------------------GDGLETSTSGVDDVSGIPTG------------------REGLETSASGVEDLSGLPSGE------------------EGSETSTSGIEDISVLPTGGESLETSASGVGDLSGLPSG------------------GESLETSASGAEDVTQLPTE------------------RGGLETSASGVEDITVLPTG------------------RESLETSASGVEDVSGLPSG------------------REGLETSASGIEDISVFPT----------------------------------------------------------------------------------------------EAEGLDTSASG----------------------------------------------------------GYVSGIPSGGDGTETSASGVEDVSGLPSG------------------GEGLETSASGVEDLG--PSTRDSLETSASGV-DVTGFPSGRGDPETSVSGVGDDFSGLPSGKEGLETSASGAEDLSGLPSGKEDLVGSASGALDFGKLPPGTLGSGQTPEVNGFPSGFSGEYSGADIGSGPSSGLPDFSGLPSGFPTVSLVDSTLVEVITATTSSELEGRGTIGISGSGEVSGLPLGELDSSADISGLPSGTELSGQASGSPDSSGETSGFFDVSGQPFGSSGVSEETSGIPEISGQPSGTPDTTATSGVTELNELSSGQPDVSGDGSGILFGSGQSSGITSVSGETSGISDLSGQPSGFPVFSGTATRTPDLASGTISGSGESSGITFVDTSFVEVTPTTFREEEGLGSVELSGFPSGETELSGTSGTVDVSEQSSGAIDSSGLTSPTPEFSGLPSGVAEVSGEFSGVETGSSLPSGAFDGSGLVSGFPTVSLVDRTLVESITQAPTAQEAGEGPSGILEFSGAHSGTPDISGELSGSLDLSTLQSGQMETSTETPSSPYFSGDFSSTTDVSGESIAATTGSGESSGLPEVTLNTSELVEGVTEPTVSQELGHGPSMTYTPRLFEASGDASASGDLGGAVTNFPGSGIEAS-VPEASSDLSAYPEAGVGVSAAPEASSKLSEFPDLHGITSAFHETDLEMTTPSTEVNSNPWTFQEGTREGSAAPEVSGESSTTSDIDTGTSGVPSATPMASGDRTEISGEWSDHTSEVNVAISSTITESEWAQPTRYPTETLQEIESPNPSYSGEETQTAETTMSLTDAPTLSSSEGSGETESTVAD--------------------------------------QEQCEEGWTKFQGHCYRHFHDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQWIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCKKGTVACGDPPVVEHARTLGQKKDRYEISSLVRYQCTEGFVQRHVPTIRCQPSGHWEEPRITCTDPNTYKHRLQKRSMRPTRRSRPSMAH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07897-1", "uniprot_id": "PGCA_RAT", "id": "P07897-1", "name": "Aggrecan core protein", "aln": "-MTTLLLVFVTLRVIAAVISEEVPDHD--NSLSVSIPQPSPLKALLGTSLTIPCYFIDPMHPVTT---APSTAPLTPRIKWSRVSKEKEVVLLVATEGQVRVNSIYQDKVSLPNYPAIPSDATLEIQNLRSNDSGIYRCEVMHGIEDSEATLEVIVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRTVGARLATTGQLYLAWQGGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYLHANQTGYPDPSSRYDAICYTGED-----FVDIPENFFGVGGEEDITIQTVTWPDLELPLPRNITEGEARGNVILTAKPIFDMSPTVSEPGEALTLAPEVGTTVFPEAGERTEKTTRPWGFPEEATRGPDSATAFASEDLVVRVTISPGAVEVPGQPRLPGGVVFHYR-PGSTRYSLTFEEAQQACIRTGAAIASPEQLQAAYEAGYEQCDAGWLQDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSSETYDVYCYVDKLEGEVFFATQMEQFTFQEAQAFCAAQNATLASTGQLYAAWSQGLDKCYAGWLADGTLRYPIVNPRPACGGDKPGVRTVYLYPNQTGLPDPLSKHHAFCFRGVSVVPSPG----GTPTSPSDIEDWIVTRVEPGVDAVPLEPETTEVP--------YFTTEPEKQTEWEPAYTPVGTSPLPGIPPTWLPTVPAAEEHTESPSASQEPSASQVP------------------------------------------------STSEEPYTPSLAVPSGTELPSSGDTSGAPDLSGDFTGSTDTSGRLDSSGEPSGGSESGLPSGDLDSSGLGPTVSSGLPVESGSASGDGE-IPWSSTPTVDRLPSGGESLEGSAS-----------------ASGTGDLSGLPSG------------------GEITETSASGTEEISGLPSG------------------GDDLETSTSGIDGASVLPTG------------------RGGLETSASGVEDLSGLPSGE------------------EGSETSTSGIEDISVLPTG-ESPETSASGVGDLSGLPSG------------------GESLETSASGVEDVTQLPTE------------------RGGLETSASGIEDITVLPTG------------------RENLETSASGVEDVSGLPSG------------------KEGLETSASGIEDISVFPT----------------------------------------------------------------------------------------------EAEGLETSASG----------------------------------------------------------GYVSGIPSGEDGTETSTSGVEGVSGLPSG------------------GEGLETSASGVEDLG--LPTRDSLETSASGV-DVTGYPSGREDTETSVPGVGDDLSGLPSGQEGLETSASGAEDLGGLPSGKEDLVGSASGALDFGKLPSGTLGSGQTPEASGLPSGFSGEYSGVDIGSGPSSGLPDFSGLPSGFPTVSLVDSTLVEVITATTASELEGRGTISVSGSGEESGPPLSELDSSADISGLPSGTELSGQTSGSLDVSGETSGFFDVSGQPFGSSGTGEGTSGIPEVSGQAVRSPDTTEIS---ELSGLSSGQPDVSGEGSGILFGSGQSSGITSVSGETSGISDLSGQPSGFPVLSGTTPGTPDLASGAMSGSGDSSGITFVDTSLIEVTPTTFREEEGLGSVELSGLPSGETDLSGTSGMVDVSGQSSGAIDSSGLISPTPEFSGLPSGVAEVSGEVSGVETGSSLSSGAFDGSGLVSGFPTVSLVDRTLVESITLAPTAQEAGEGPSSILEFSGAHSGTPDISGDLSGSLDQSTWQPGWTEASTEPPSSPYFSGDFSSTTDASGESITAPTGSGETSGLPEVTLITSELVEGVTEPTVSQELGHGPSMTYTPRLFEASGEASASGDLGGPVTIFPGSGVEAS-VPEGSSDPSAYPEAGVGVSAAPEASSQLSEFPDLHGITSASRETDLEMTTPGTEVSSNPWTFQEGTREGSAAPEVSGESSTTSDIDAGTSGVPFATPMTSGDRTEISGEWSDHTSEVNVTVSTTVPESRWAQSTQHPTETLQEIGSPNPSYSGEETQTAETAKSLTDTPTLASPEGSGETESTAAD--------------------------------------QEQCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQWIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCKKGTVACGEPPAVEHARTLGQKKDRYEISSLVRYQCTEGFVQRHVPTIRCQPSADWEEPRITCTDPNTYKHRLQKRTMRPTRRSRPSMAH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16112-1", "uniprot_id": "PGCA_HUMAN", "id": "P16112-1", "name": "Aggrecan core protein", "aln": "-MTTLLWVFVTLRVITAAVTVETSDHD--NSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTT---APSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGED-----FVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTFAPEIGATAFAEVENETGEATRPWGFP---TPGLGPATAFTSEDLVVQVTAVP------GQPHLPGGVVFHYR-PGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSG-EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSG-------------------LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSS-GLGVSGSTLTFQEG--EASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQKRSSRHPRRSRPSTAH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDA1-1", "uniprot_id": "F1QDA1_DANRE", "id": "F1QDA1-1", "name": "Aggrecan core protein", "aln": "-MLSLLLLSMCLWVFSATASFDYIDTEPESPLRVSIPNELPLRPLMGDTLVLPCYFQDNTVNDPG---APTIAPLSHRIKWSLVTKEKTTNILVASEGIVSIEKRYMDRITLVGYPMTPTDASIKITELHSNDSGVYRCEVMQGIEDSHDIVDVQVQGIVFHYRAITTRYTLNFEKAKAACIQNSAVIATPEQLQAAYDEGFHQCDAGWLADQTVRYPIHDPREACYGDKYEFPGVRTYGVRDVNETYDVYCFAERMTGKVFHTTSPNKFTFEEAEAQCSKLGAKLATTGQLYLAWKGGMDVCNAGWLADRSVRYPINIARPQCGGGLLGVRTVYLFPNQTGYPHPDSRYDAFCYSETGDEGSGFFPLDLELTTDGDNGVLTVDTITESHTVISKP-ASTESEVQG-EVVTYKPSVTTS-----VENPYT-ALDISHVLPSPPTSSVEKD-------------PDFGSGLSQSNKTEDTMSAT-------------GVVFHYRGGNCSRYPFGFVEAQLACKSIGAVIASAQQLQAAYEAGYHQCDAGWLSDQTVRYPIVSPRHQCSGDMEQVPGVRSYGLRPADERYDVYCYVDKLRGQVFHASSFEGFTYGEAVAHCQGQNASLASTAHLYAAWKQGFDKCRAGWLLDRSVRYSINIPRQQCGGGRTGVHTVYLFPNQTGSPDLHSKFDAYCFK----------------------------------EDLDLPLNESESQ----------ETVTEEKIVSISSHPALHRPEGTPIIAPSPTEPSGTEESVASSSGDLLSSGSGDQ-----------------------------------------------PSGSSVSSGDSSGTSSTDDLLTSG--------SGDQSGSGSSVTSGDYSGAS--GTDSLFSSGSGDRS-------SGSFSSSGDFSG---------------------------------------------ASGTDDLLGSGSGE-----------------------QPSGSFVSSGDFSG-------------------------------------------------------------ASGSGD-----------------------------------------------------MSSGSGSSSGSGSG-------------------------------------------------------------------LDILVTFSG---------------------IDTVFSGVGSTSGQLEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGEGSTEILTFQLDQISGSGSG------------------------------------------LGSGSGYSSEESGSTSDLSSSSGESGESGDLSGIS-SGSGFSEESS---------------------------------------GFSGFASGIFPSGGSSDISFIDGSGI--------------IMVDRPWMKISSFLTEQELGSGQVDFSG------------------SGLFSGSGVSGDISG-------------LSGEISGSSGDSSG----------------------------ISSDISGMSGDISGMSG---------DISGISGDITGMSGDLSGMS-------------SSDHSGSGSGLAFSGVTF--------------------------------LGSGFTDLTEQSREQEASGLVFFGSGEGSGFRSGGYAI---------------ESGERSGDSASSDVIFFSNNDMVEMSNKPLQGMELGRGE---VEYSGTVRLSSGSGDDQSVFISGHEWIPVTANTPSVKSTDPPPAELFD--QGPSDLYSDTAGHLGPYLKPEEIINNLDAVPLAALSSTTETASLQRPAVVERPAVNDY-LNPCEPNPCG-----------------------------------------------------------------------AGVCSVKDGVGLCHCPPGLHGE------------------------------------------------------------ECQFEVDVCHSNPCANGATCVEVEDTFKCLCLPSYEGDRCETDS-------------------------------------------HSCEKGWTKFQGNCYLHFSKRETWLDAEQRCRDLNAHLVSINTPEEQAFVNSNAQDYQWIGLNDKTVENDFRWSDGTQLQFENWRPNQPDNYFNSEEDCVVMIWHENGQWNDVPCNYHLPFTCKSGPVTCDKPPKVENAKMFGNKKERYQVNSIIRYQCSENFTQRHPPVIRCMADGQWEKPKVQCIPKVKFG--LHDKSVHHSHKAR--TALEKQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TGD0-1", "uniprot_id": "A0AB32TGD0_DANRE", "id": "A0AB32TGD0-1", "name": "Aggrecan core protein", "aln": "MSLIWLLLYICTHGISGMILFGDMADQ-DSTLSVSIPVEQPLRPLLGGSMVIPCYFQDITLQDPGTLTSPTNAPLSQRIKWSHIHKGKISLILVATEGQVQVETEYLDRVHLVNYPMVPSDATIEISELRSHDSGTYRCEVMQGIDDNYDSVEMQIQGIVFHYRAISTRYTLTFEMAKAACIQNSAVIATPAQLQAAYDDGFHQCDAGWLSDQTVRYPIHEPREPCYGDKDNFPGVRTYGVRDVNETYDVYCFAEKMSGRVFYSMSVEKFTFADAEDQCAKLGAQLATTGQLYLAWKTGMDVCNAGWLADRSVRYPINIARPQCGGGLLGVRTVYLFPNQTGYPYPDSRYDAICYEDKEDKVLIKTTPFPEIYTTTES-VLTVATVTSSSSDYTEQ-VTTEGEVRG-QILTDEPFNTTS-----TESPLSPPLNITDVEEDIINVATAP--------------PSLEHAIPSIN---VTAKIK-------------GVVFHYR-AESGRYAYTYEEAQDACQKLGAVIATPELLQAAYEAGLHQCSAGWLQDQTVRYPIVHPRKKCSGDSEDVPGVRSYNVRPAHEQYDVYCYMDQIKGEIFHVSSLAGFTYYEAVAHCRKLSSTLASTGELYAAWNQGFHKCSPGWLADRSVRYPVGSPDFDCGGNKTGVQTIYAQPNQTGSPHPYSRYDAYCFK----------------------------------ANLSLGFDED--------------------MLNATDITMLQRP-VHPIVPPLFVDMSG----SGSGSGYASASTSG--------------------------------------------------SGSDSASGSASGVPDSSSGYISG--------SGIASGSAS------GSGQS--GDGSGFLVRYQEGT-------DALMWSS--------------------------------------------------ASGSASEAKDGSG--------------------------SGIIITSGIQSG-------------------------------------------------------------DQESGE-----------------------------------------------------ESGHFAVASGLPSG-------------------------------------------------------------------LGSGISGSG---------------------TSGFFSGEES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGSGFFSVSFVDTKMIDLTARAFGEQ-ELSGFYTAESGFPSGSG---------------------------------------SFSGFETG-------SAIGFESNS---------------------------------AFGSG------------------------SGFETGSAIGFESNS-------------ASAFGSGSSSGFE-----------------------------SSSAFGFGSGSASGFG------------SGIASGIE--SSPASAFG-------------SGSASGFGSSSAIGLESS--------------------------------SASGFKSVSVTG----TSGYPNHPSGEVS------------------------ENIQRQ----DGEMIIFTDDEVTELTLRPTAGTEQGRGS---VEISGEGSTPEPYTEDS---IS-------VSNSTSHESNDLLPERDEK--ISVTMEAFDVTDKS-------PLITTPTNIP---VLTTPSSASLQMPKSTMNPSVNEAPFDPCDPNPCG-----------------------------------------------------------------------QGLCSLQDGVALCQCHSGFSGE------------------------------------------------------------NCSMLVQG---------------------------------------------------------------------------------CAEGWMEFMGSCYIHFDERETWTSAEQHCQELNSHLVSISSQQEQEFVKTQAQDYQWIGLNDKDVQNEFRWTDGSPLEYENWRPNQPDNYFSTGEDCVVMIWHENGQWNDVPCNYHLPFTCKSGPVTCTTPPEVQNARMLGNSKDRYPVNSFIRYQCNSGFTQRHLSVVRCLPDGQWEKPRVECIRGIENNR-LRKRSLYIRPKAVNSRTWRKVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : ::. : ..* **** **: *:* ::.:**** * . :*: ***: ***** : * * :***:** * ::. * *:: * .** *:**:::: .*:*:*** ******:**:*. ::: ::*********:***** *: *: **:****:**** ******::**********:********* *** ***** :********:**.***********.* *.**:: * :**** :* :* :**:***********: ***:*.*************. ***:***.********:..****** *.*****:** :: . :*: *:* . . **.*. * ::* :* * .. : . :: . . . .:.. : . ******* **. : *** ** **.**:.: ******** .**.**** ********* ** * ** :. ****:*.:**: * *****::*::.*::*..: : **: ** .* .::**:*..*****.:*:.** .*** * ::**.: * ***.:.**:*:* ***** *. *:..*:**: : : . . . : . * .. .. . *. .* * * *. . : ... . ** ** :** . ** . * : : : .. .* *** . ** .* ** ** .* : ** ** . :* . .* . *.** . : . : ::**: . .*: :. .*: :* :. * * * **: :*: :. : .. *. * .. ** **. **. ** :..: *. *.: *. ** *.. .: ** .:: *. : * * . . : : : :.* . . * *.* :* ** . : :. :.. . . : . : . .* . : * . * : : . . .. . . :.::* . . . ** : : * :** :: * ** ** .**** .**::*:: ::** ** : :** **:.:***********: ::.:***:** :::*:********:* : **********.*:********:******.*.*:* ** *::*: :*:.*:** :.*::****...*.*** ..:** ....**:*:: * *:.:: :: : ", "identical_positions": 497, "similar_positions": 353, "identity": "19.28%" }, { "cls_id": "homologset.agr.HGNC:31909", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89010-1", "uniprot_id": "O89010_MOUSE", "id": "O89010-1", "name": "", "aln": "MADFHNTQYCNLEESAQAQQE-SDNDQETMETSEEEEDTTTS----NKVYGSAIPSPPQSPQRAYSPCVALASIPDSPSEEASIKGSGGLE----DP---LYLLHSAQNTKVYDLVDFLVLNYEMKAFPTKAEMLESIGREYEEYFPVIFSEASECLKMVFGLDMVEVDPSVHSYMLVTALGITYDGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEVIWEMLNNIGLCGGRDP-YIHKDPRKLISEEFVQEGYLEYR--QVPNSDPPIYGFLWGPRALAETSKMKVLQFFASINKTHPRAYPEKYAEALRDEIERTKAWILSRCSNFSDHSSVLPFPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89009-1", "uniprot_id": "O89009_MOUSE", "id": "O89009-1", "name": "", "aln": "MADFHNTQYCNLQESAQAQQE-LDNDQETMETSEEEEDTTTS----NKVYGSGIPSPPQSPQRAYSPCVALASIPDSPSEEASIKGSEGLE----DP---LYLLHNAQNTKVYDLVDFLVLKYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEIDPSVHSYILVTALGITYDGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMLNNIGLYGGRNP-YIHKDPRKLISEEFVQEGYLEYR--QVPNSDPPSYGFLWGPRAFAETSKMKVLQFFASINKTHPRAYPEKYAEALQDEIDRTKAWILNRCSNSSD---LLTF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZW04-1", "uniprot_id": "D3ZW04_RAT", "id": "D3ZW04-1", "name": "", "aln": "MDDAHNIQYSNLQDNAQAEQE-LDNAQATMAAAEEEEATSTS----KAEYGSGIPSPLQSPERACSPSVALASIPVGPSEEASIRQLEALE----DP---LYLLHNAQNVKVYDLVDFLLFKYQTKAFTTKAEMLETIGREYDEYYPLIFSEASECMKLVFGLDIVEVDPSVHSYVLVTALGITYDGMLTDVQGMPKTGVLIVVLGVIFMKGNYVSEDIIWEMLNNIGLCGGMDP-YIHRDPRKLISEEFVQEGYLEYR--QVPNSDPPSHVFLWGPRAFAETTKLKVLQFFASITKTHPRAYPEKYAEALRDEIDRVEAWIFQQMLRHL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F2Z493-1", "uniprot_id": "F2Z493_MOUSE", "id": "F2Z493-1", "name": "", "aln": "MENPDNTHYCSLQGSARSQRE-LDNVQATIAVVDEEEATPTS----KKVYSSGIPSPPQSPQRASSPLVILASVPEGPSEEASTNQVEEQE----DP---LCMLYNAQNIKLYELATFLFFKYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECFKLVSGIGMIEVDPFVQSYILVPALGLTYDGMLTDVQSKPKTGILIVVLGAIFTQGNCVSEEIIWKMLNNIGLYGGRHL-YIHQDPRKFISEEFVQEGYLEYR--QVPNSDPPSYEFLWDPRAFAETTKMKVLEIFASITMTDPRAYTEKYAEALRDETERAQARIIQQIVLQL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43362-1", "uniprot_id": "MAGA9_HUMAN", "id": "P43362-1", "name": "Melanoma-associated antigen 9", "aln": "MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDSKEEEVSAAGSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYILVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEH-MFYGEPRKLLTQDWVQENYLEYR--QVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "----------------------------------------------------------------------MASTSRAARSQNAIPSQEAQQ-----P-------VDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVAGDKSE--LKKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVASIHELTPAQR-PQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: : * .. . *: : ::. : * .. ::: : . : .:: : * : :*. :::: .. :: : : *: :* :* *: :.* :. :: *. :.: . . : : ** : : :*:: **: . *:. * . ***..:* ** : :::: : .* : . ", "identical_positions": 25, "similar_positions": 79, "identity": "7.35%" }, { "cls_id": "homologset.agr.HGNC:31910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1YIY0-1", "uniprot_id": "FCRL6_MOUSE", "id": "A1YIY0-1", "name": "Fc receptor-like protein 6", "aln": "MLLWMVLLLCE-----------------------------------------------------------------------------------------SMAEAQELFPNPELTEFTNSETMD---VILKCTIKVDPKNPTLQLFYTFYKNNHVIQDRSPHSVFS-AEAKEENSGLYQCMVDTEDGLIQKKSGYLDIQFWTPVSHPVLTLQHEATNLAVGDKVEFLCEAHQGSLPIFYSFYINGEILGKPLAPSGRAASLLASVKAEWSTKNYSCEAKNNISREISELKKFPLVVSGTAWIKS-NMLPIWLPASLLGGMVIAAVVLMYFFKPCKKHARPETPTLKEP---DSFLYVSVDNQRYK---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23505-1", "uniprot_id": "GP42_RAT", "id": "P23505-1", "name": "Cell surface glycoprotein gp42", "aln": "MLLWMVLLLCV-----------------------------------------------------------------------------------------SMTEAQELFQDPVLSRLNSSETSD---LLLKCTTKVDPNKPASELFYSFYKDNHIIQNRSHNPLFFISEANEENSGLYQCVVDAKDGTIQKKSDYLDIDLCTSVSQPVLTLQHEATNLAEGDKVKFLCETQLGSLPILYSFYMDGEILGEPLAPSGRAASLLISVKAEWSGKNYSCQAENKVSRDISEPKKFPLVVSGTASMKS-TTVVIWLPVSCL----VGWPWLLRF--------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DN72-1", "uniprot_id": "FCRL6_HUMAN", "id": "Q6DN72-1", "name": "Fc receptor-like protein 6", "aln": "MLLWTAVLLFVPCVGKTVWLYLQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMGAATVQSRGQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTKLHPLRSALRLLFSFHKDGHTLQDRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAPCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVPWLPASLLGLMVIAAALLVYVRSWRKAGPLPSQIPPTAPGGEQCPLYANVHHQKGKDEGVVYSVVHRTSKRSEARSAEFTVGRKDSSIICAEVRCLQPSEVSSTEVNMRSRTLQEPLSDCEEVLC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** .:** :*.:.**** * *: : ..*. : : *:* *:.* ..: .*:::*:*:.* :*:*. :. : . *:* :**** * * .:.* :**:* *:: . :.**:*****:* .:: * ** *::***:: ** **:****:: :*:*: **.* ::*** .**:* . ****:*:*.:**: ** **:.* * . : . : ***.* * :. *: . ", "identical_positions": 91, "similar_positions": 82, "identity": "20.97%" }, { "cls_id": "homologset.agr.HGNC:31911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IZJ4-1", "uniprot_id": "RGDSR_HUMAN", "id": "Q8IZJ4-1", "name": "Ral-GDS-related protein", "aln": "-------------------------------------------------------MRKLLTNLPAAAVLSAQVYSAVLQG--------LWEENVCGTPGR----------------------------------------------------TRVCTALLYGQVCP------FQDSTDGLRTITSILFN-----WPPENTS-----------VYYQPPQRSSFRIKLAFRNLSWPGLGLEDHQEIVLGQLVLPEPNE-------------------AKPDDPAPRPGQ-----HALTMPALEPAPPLLADLGPALEPES-----------------------------------------------------PAALGPPGYLHSAPGPAPAPGEGPPPGTVLEPQSAPESSCPCRGSVKNQPSEELP-----------------------DMTTFPPRLLAEQLTLMDAELFKKVVLHECLGCIWGQGHLKGNEHMAPTVRATIAHFNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQLHKTWAGVSSKSMKELKELC-----KKDTAVKRDLLIKAGSFKVATQ-----ERNPQRVQMRLRRQK-KGVVPFLGDFLTELQRLDSAIPDDLDG----NTNKRSKEVRVLQEMQLLQVAAMNYRLRPLEKFVTYFTRMEQLSDKESYKLSCQLEPENP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PCE9-1", "uniprot_id": "M9PCE9_DROME", "id": "M9PCE9-1", "name": "", "aln": "MNFTSRANCKCPHSQKHQQKPALIKSHTCAYQLQDLTGYNRALMPPLDNTDFSNAWRQVNNNTTSQSCAYHQQRQQQQQQQDAKDSKRHYHHHTCPRQRKKSMTPVEPTHLCQKHQEAKQRRSRSASAKPRRNSSYHSYDDLDVSSAVLNAERKVVASLKYLCACTGATLRNLSKKTKDLHAKNYTYTKPTWRLWGEEHEKNAIFTVYLKKVRYHRPTPTASNDSDDEISHLEWETVRVRFVKAATLARLVEALATDDGELESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPAYDPHASIHEQHKKTLVSALHVWLDGFPEDWHEDNLQQILAFATKRLKRSDLHIKVLNRLERLIKQSLYGNGGGSGGSENNGHSWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPTHFLQAFRFPHVPVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSGGSE----TVVATINQFNAVLFRVVSSILIDR-LKPQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKIWEVLPKERMEVFTELANICSEDNNAWTLREVLKREGTAKNPDPGSDHSDRHLQKLILNLGTQTSHGTIPYLGTFLTDLTMIHTANPDYLTENKLINFDKKRKEFEVLAQIKLLQGAANTYNLQADALFDHWFNSMPVFDEREAFELSCRLEPPPPAPRKSVVSTNTSLTNTTASSTASIMGHRKTDSIHSNSSSGAGSQFYCELNSSTSSRHNSLDRDVHHQHASLMSASSSVSNLSLDSSNSGGRQSGKLTHSQSMGNGLKSHGNGTTNGGSPHINAQLVQPSSGTPHSAPDFYIIRVTYETDNIELDGIVLYKSIMLGNNERTPQVIRNAMLKLGLEDDPDRFTLAQVLPDKELVMPKNANVYYAVNTNYNLNFILRPRKEEGVAGSXSTAVPLSQLWCLGYEGEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: .* .: : * . * :..:.* : :* ::* * .*. :...*..*:: . : * *: . *::*. :* . : :*.* : :. : .*.:** . ..: :.*.: . * * : ** * :.** :*.: * . .. *.. : .:* . :. ..*. : * : . . : :::: :. .* * :***** **:****::: *:*** *.: . *.* ** *** :** : :.:* * *: ::.::** :.:**.:*:* *:****::.*:*** **.* :* * * :..: *: :.**. .::: . *::* : *: * . :*: *:: :.* *. :*.:*:** ***:* :.:* ** * * :*: **..** :::*** ** .*.*:. * :*. * :.::*:::***:*** * ", "identical_positions": 133, "similar_positions": 174, "identity": "13.6%" }, { "cls_id": "homologset.agr.HGNC:31914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKQ8-1", "uniprot_id": "D3ZKQ8_RAT", "id": "D3ZKQ8-1", "name": "Tumor necrosis factor receptor superfamily member 17", "aln": "MAQRCFHSEYFDSLLHACKPCRLRCSNPPAPCQPYCDPSMTSSVRGTYTVLWIFLGLTLVVCLALFTLSFLLRKMNPEALKDKPQSPGHLDGSVQLDKADTERTKSRAGDERILPRSLEYTVEECTCEDCIKSNPKGDSDHFFPLPAMEEGATILVTTKTGDYGKGLQNDDRRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGMKRSRGLALTAAAIKQAAGFTSKTETEPVFWVYVKEVLSKHELQRFYSLHHITADVGRGRAWLRCALNEHSLERYLHMLLADRTRLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNMTSLLKESTQGMSSLLREITASSAVSILIKPEQETDPLPVISKNVHVDARCKRERRRRKKVTNIVSFDDDDEEQGAGDTLKKMPGTAESSEENSDRSSVNIMAAFEGPFGPNSNGSQSSNSWKMDSASLNGELGYQKLDVKSIDD-DVDESEEAVYRNPLGRGHTGHKESPDRTLDGNASLPQVHGWAPLQVLHGDADADTDILFPVSGVGSYGTADAPVGSLENGTGTEDHILPEPGLRYREAGSPGRGSPLSSLLPSASVPESMTVHELRQAIVAMMNRKDELEEENGSLRNLLDGEMEHSAALRQEVDALRRKVTEQQERHATKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVVPSLWNVDAEVTVPEQKPGEVAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAYHVYQVYIRIKDDEWNVYRRYTEFRGLHHQLQSAFPQVRAYSFPPKKAIGNKDAKFVEERRKQLQSYLRSVMNKVIQMVPEFAANPKKETLVQLVPFFVDITPPGEPLSKSSRPKVVSRFPKLSRGHPREVRNVEPQSGDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3S3-1", "uniprot_id": "SNX29_MOUSE", "id": "Q9D3S3-1", "name": "Sorting nexin-29", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGSQNDDRRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGMKRSRGLALTAAAIKQAAGFTSKTETEPVFWVYVKEVLNKHELQRFYSLHHITSDAGRGRAWLRCALNEHSLERYLHMLLADRARLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGMSSLLREITASSAVSILIKPEQETDPLPVISKNVHVDTRCKRERRRRKKVTNIVSFDDDEEEQGTGDTLKKMPGTAESSEENSDRSSVNIMAAFEGTFGPNSNGSQSSSSWKIDSASLNGELGYQKLDVKSIDD-DVDENEEDAYRSPLGRGHTGHAESPDRTLDGNACLAQVHGWAPLQVLHGDADADTDVLFPVSGVGSYGAADAPVGSLENGTGTENHIIPEPGLRYREASSPGQGSPLSSLLPSASVPESMTVHELRQAIVAMMNRKDELEEENGSLRNLLDGEMEHSAALRQEVDALRRKVTEQQERHATKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEAVPSLWNVDAEVTVPEQKPGEVAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYTEFRALHHQLQSAFPQVRAYSFPPKKAIGNKDAKFVEERRKQLQSYLRSVMNKVIQMVPEFAANPKKETLVQLVPFFVDITPPGEPLNKSSRPKAVSRFPKLSRGHPREVRNVEPQSGDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUI4-1", "uniprot_id": "S29P2_HUMAN", "id": "Q8IUI4-1", "name": "Putative protein SNX29P2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEERSSMLPTMAAGPNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVT-LLKESTQGVSSVFREITASSAISILIKPEQETDPLPVVSRNVSADAKCKKERKKKKQVTNIISFDDEEDEQNSGDMFKKTPGAGESSEDNSDHSSVNIMSAFESPFGPNSNGSQSSNSWKIDSLSLNREFGYQKLDVKSIDDEDVDENEDDVYGNSSGRKHRGHSESPE---------------------------------------------------KNGA----HSVTQAGVQWHDLSS------LQPLPPGFK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *************** **********************************:* ********:**::********:***************:*:** .*::**:**:::*:****:****:::**.:** :** **:.****:***:******:***..***********.***:** *** *:************ ****.*: .* .. ** * ** ***: :**: * :.:.*::::: .* *..* *. . ", "identical_positions": 178, "similar_positions": 54, "identity": "18.13%" }, { "cls_id": "homologset.agr.HGNC:31918", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32ZH8-1", "uniprot_id": "DFB13_RAT", "id": "Q32ZH8-1", "name": "Beta-defensin 13", "aln": "----MRIFSLIVAGLVLLIQLHPAKGTLYRRFLCKKMKGRCETACLSFEKKIGTCRADLTPLCCKEKKKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2I4-1", "uniprot_id": "DFB13_MOUSE", "id": "Q8R2I4-1", "name": "Beta-defensin 13", "aln": "----MRIFSLIVAGLVLLIQLYPAWGTLYRRFLCKKMNGQCEAECFTFEQKIGTCQANF--LCCRKRKEH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZN7-1", "uniprot_id": "D107A_HUMAN", "id": "Q8IZN7-1", "name": "Beta-defensin 107", "aln": "MPGAMKIFVFILAALILLAQIFQARTAIHRALISKRMEGHCEAECLTFEVKIGGCRAELAPFCCKNRKKH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:** :*:*.*:** *:. * :::* ::.*:*:*:**: *::** *** *:*:: :**:::*:*", "identical_positions": 28, "similar_positions": 27, "identity": "40.0%" }, { "cls_id": "homologset.agr.HGNC:3192", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62631-1", "uniprot_id": "EF1A2_MOUSE", "id": "P62631-1", "name": "Elongation factor 1-alpha 2", "aln": "MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62632-1", "uniprot_id": "EF1A2_RAT", "id": "P62632-1", "name": "Elongation factor 1-alpha 2", "aln": "MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05639-1", "uniprot_id": "EF1A2_HUMAN", "id": "Q05639-1", "name": "Elongation factor 1-alpha 2", "aln": "MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05303-1", "uniprot_id": "EF1A2_DROME", "id": "P05303-1", "name": "Elongation factor 1-alpha 2", "aln": "MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYEEIKKEVSSYIKKIGYNPASVAFVPISGWHGDNMLEPSEKMPWFKGWSVERKEGKAEGKCLIDALDAILPPQRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGLLKPGMVVNFAPVNLVTEVKSVEMHHEALTEAMPGDNVGFNVKNVSVKELRRGYVAGDSKNNPPRGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFSEIKEKCDRRTGKTTETEPKAIKSGDAAIIVLVPSKPLCVESFQEFPPLGRFAVRDMRQTVAVGVIKSVNFKETTSGKVTKAAEKAQKKK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08736-1", "uniprot_id": "EF1A1_DROME", "id": "P08736-1", "name": "Elongation factor 1-alpha 1", "aln": "MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYNPAAVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGNADGKTLIDALDAILPPARPTDKALRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPPKGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFAEIKEKVDRRSGKTTEENPKFIKSGDAAIVNLVPSKPLCVEAFQEFPPLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAAEKATKGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02994-1", "uniprot_id": "EF1A_YEAST", "id": "P02994-1", "name": "Elongation factor 1-alpha", "aln": "MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVK--WDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVD-KTEKAAKVTKAAQKAAKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***:************************************ *:**************************:******.** :*:***********************:**:*.*.*********:**********:****:****.****** : :.* *::** **.* :***:**** :*.*******:****:*.: : **:***. * * * ..* *::*:*:* * *****.*************************:::** ** ***..:.*********** * :.:***************::*** *.**:* :**: .*.*.: **:*******: **:**:*********:* *: ** ***:**. * .** :******:: :**.**:***:*.::********************* *: * ..****:*:** * ", "identical_positions": 335, "similar_positions": 82, "identity": "72.35%" }, { "cls_id": "homologset.agr.HGNC:31921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z9L9-1", "uniprot_id": "A1Z9L9_DROME", "id": "A1Z9L9-1", "name": "Solute carrier family 25 member 35", "aln": "--------------------MATSDFVLGGVAAMGAGVFTNPVEVIKTRIQLQGELAARGSHAQPYKSVFQAFVTVAKNDGILGLQKGLAPALCFQFVINSFRLSIYT-HAVEKGWVHNNKGEISFAKGM----FWGALGGVVGSYCASPFFLIKTQLQAQAAKQIAVGYQHQHASMSDAIRKIYRKNGVFGLWRGSLANVSRATVASAVQIAVFGQAKSLLKENGVVT-HPTILSFCSGLAAGSFVSLAITPLDVVTTRLYNQGVDAQGRGIYYRGWLDCVLTILRSEGVYGLYKGFWPIYLRSAPYSTLVLLFFDELIALREKYDLHY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9M0-1", "uniprot_id": "A1Z9M0_DROME", "id": "A1Z9M0-1", "name": "Solute carrier family 25 member 35", "aln": "--------------------MTKSDFVLGGTAAMGAVVFTNPIDVVKTRMQLQGELAARGTYVKPYRHLPQAMLQIVLNDGLLALEKGLAPALCYQFVLNSVRLSVYS-NALELGYLQNADGSISFYRGM----FFGALGGCTGTYFASPFYMIKAQQHAQAVQSIAVGFQHKHTSMMDALLHIYRTNGISGFWRAALPSLNRTLVASSVQIGTFPKAKSLLKDKGWIT-HPVLLSFCAGLSSGTLVAVANSPFDVLTTRMYNQPVDEKGRGLMYKGLVDCFTKIWRTEGIHGMYKGFWPIYFRSAPHTTLTFVFFEKLLHLRDRYVFSQRRN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3KQZ1-1", "uniprot_id": "S2535_HUMAN", "id": "Q3KQZ1-1", "name": "Solute carrier family 25 member 35", "aln": "-----------------------MDFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNGIRLGTYG-LAEAGGYLHTAEGTHSPARSA----AAGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQGKGLMYRGILDALLQTARTEGIFGMYKGIGASYFRLGPHTILSLFFWDQLRSLYYTDTK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SWT3-1", "uniprot_id": "S2535_MOUSE", "id": "Q5SWT3-1", "name": "Solute carrier family 25 member 35", "aln": "-----------------------MDFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKGLGPALLYQFLMNGIRLGTYG-LAESRGYLHTNEGTHSPVRSA----AAGALAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQLRSFYNTYAK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L7L9-1", "uniprot_id": "A0ABK0L7L9_RAT", "id": "A0ABK0L7L9-1", "name": "", "aln": "-----------------------MDFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKGLGPALLYQFLMNGIRLGTYG-LAESGGYLRTKEGTHSPVRSA----AAGALAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSTKDLLSQWEIFPPQSWKVALAAAMVSGVAVVLAMTPFDVASTRLYNQPTDTRGKVLS-------ILETHRIQSIK-LHTTEPSHLFYLAKVNSLQVPTGEMLGEWGGPTTL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KPP4-1", "uniprot_id": "S2535_DANRE", "id": "A3KPP4-1", "name": "Solute carrier family 25 member 35", "aln": "-----------------------MDFILGGVAACGACFFTNPLEVVKTRMQLQGELKSRGTYQVYYRNVFHAFYTIGKIDGLAGLQKGLVPGLVYQFFMNGVRLGSYA-LTESLGYIHT-DGRVSATKST----VSGAIAGVVGAVMGSPIYLVKTHLQSQSTSSIAVGHQYKHRGMTNALFAIHKQHGILGLWRGASAAIPRVSVGSAAQLATFSASKEMVNDLQVFSEGSWLIALSAGMISSVVVVLAMTPFDVVSTRLYNQPVDHLGKGMLYRGFVDCFSKTLKKEGMTGLYKGLGASYFRLGPHTILSLLFWNELRCLHQSYS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32332-1", "uniprot_id": "OAC1_YEAST", "id": "P32332-1", "name": "Mitochondrial oxaloacetate transport protein", "aln": "MSSDNSKQDKQIEKTAAQKISKFGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSAS--AAKVYKNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHKVQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQS-YSEFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMK-DGPALHLTASTISGLGVAVVMNPWDVILTRIYNQ------KGDLYKGPIDCLVKTVRIEGVTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVYSIESRVLGHN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: .* ** * .***::::* *:*****: : *: :.: : :*: .*:*** .. :*: :*. **. * . : . :. ** .* *: .**::::*:: :: . * :* * :: .: :.: * : .*: *::*. : *. .*:.*: : *.:: . . : : :. :. : :. * ** **:*** : . : :.. ::. . : . . : . : ", "identical_positions": 52, "similar_positions": 96, "identity": "15.57%" }, { "cls_id": "homologset.agr.HGNC:31922", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15083-1", "uniprot_id": "ERC2_HUMAN", "id": "O15083-1", "name": "ERC protein 2", "aln": "--MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTS-SGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEG----VAST-TYPKG-TMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTGSSHHHHHQVPSMLRQVR---DSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQ---------HLQLTIQALQDELRTQRDLNHLLQQESGNR--GAEHFT-IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPSKS--------------LEDDNERTRRMAEAESQVSHLEVILDQK------------------------------------EKENIHLREELHRRSQ---------LQPEPAKTKALQTVIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEIQMLKANGVLNTE---------------------------------DREEEIKQIEVYKSHSKFMKTK-----------------------------IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLK---------------KAHNIEDD----------SRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES---LTLR---------------------------------------------HMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKAR-----------------------LASTQQSLAEKEAHLANLRIERR------KQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD--------------------RLVHQLKQQTQNRMKLMADNYDDDHHHYHH------------------------------------------------------------------------------------------------------------------------------------HHHHH----------------HHRSPGRSQ-------------------------------------------------HSNHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PH08-1", "uniprot_id": "ERC2_MOUSE", "id": "Q6PH08-1", "name": "ERC protein 2", "aln": "--MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTS-SGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEG----VAST-TYPKG-TMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLSGSSHHHHHQVPSMLRQVR---DSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQ---------HLQLTIQALQDELRTQRDLNHLLQQESGNR--GAEHFT-IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPSKS--------------LEDDNERTRRMAEAESQVSHLEVILDQK------------------------------------EKENIHLREELHRRSQ---------LQPEPAKTKALQTVIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEVQMLKANGVLNTE---------------------------------DREEEIKQIEVYKSHSKFMKTK-----------------------------IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK---------------KAHNIEDD----------SRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES---LTLR---------------------------------------------HMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKAR-----------------------LASTQQSLAEKEAHLANLRIERR------KQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD--------------------RLVHQLKQQTQNRMKLMADNYDEDHHHYHH------------------------------------------------------------------------------------------------------------------------------------HHHHH----------------HHRSPGRSQ-------------------------------------------------HSNHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K3M6-1", "uniprot_id": "ERC2_RAT", "id": "Q8K3M6-1", "name": "ERC protein 2", "aln": "--MYGSARTISNPEGSPSRSPRLPRSPRLGHRRTS-SGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEG----VAST-TYPKG-TMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLGGSSHHHHHQVPSMLRQVR---DSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQ---------HLQLTIQALQDELRTQRDLNHLLQQESGNR--GAEHFT-IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPSKS--------------LEDDNERTRRMAEAESQVSHLEVILDQK------------------------------------EKENIHLREELHRRSQ---------LQPEPAKTKALQTVIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEIQMLKANGVLNTE---------------------------------DREEEIKQIEVYKSHSKFMKTK-----------------------------NDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK---------------KAHNIEDD----------SRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES---LTLR---------------------------------------------HMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREFSMVDNSQHLQIEELMNALEKTRQELDATKAR-----------------------LASTQQSLAEKEAHLANLRMERR------KQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD--------------------RLVHQLKQQTQNRMKLMADNYDDDHHHYHH------------------------------------------------------------------------------------------------------------------------------------HHHHH----------------HHRSPGRSQ-------------------------------------------------HSNHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32U3W7-1", "uniprot_id": "A0AB32U3W7_DANRE", "id": "A0AB32U3W7-1", "name": "", "aln": "--MYGSARAVGHIEGSPARSPRLPRSPRLGHRRAN-SSSSG--GKTLSMENIQSLNAAYATSGPMYLSDHEG----VGSTATYPKG-TMTLGRATSRAMYGGRVTAMGSTPNIATVGIPHADLQSYGDLG---SLSLLHHQGTPSALLRQVVRGGGGELLELQAQLRDMQRENELLRRELDLKDSKLGSSTNSIKSFWSPELKKERIMRKEEAARTSILKEQMRVTHEENQHLLDSRRTKHLQLTIQALQDELRTQRDLNHLLQQESSSRAGGGDHFTTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPPASGR----------ASDEEEQERARRIAEAEAQLGHLEVILDQK------------------------------------EKENIHLREELHRRNQ---------LHPDPGKTKALQTIIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEIQMLKANGLLNTE---------------------------------DREEEIKQMEVYKNHSKFMKTK-----------------------------IDQLKQELSKKESELLALQTKLETLNNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLGNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQREREDRERMEELDSYKKENKDLKEKVNTLQVELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAIEQKKEECNKLETQLQKQAEQLF--SQMNNPKAHEVEVQQ--------SSRGNPEYVDRVKLLEKEVSYFKDESSKAQNEVERLLEILREVETEKNDKDKKIQELESPPPLATRPSPRPGGRAPSDPPPSVSAAPQQIGGMV-----------WDFLGKQTKDQIKKGPGIKLGPQMDKKGPGNILQDQRK--DNPMDNP---KMEELMNVLEKTRQELDATKQR-----------------------LSSTQQSLSERDGHLTNLRQERR------KQLEEILEMKQQALLAAISEKDANIALLELSSSNKKKTQEEVLALKREKD--------------------RLMHQLKQQTQSRMKLIADNYEDDHYHPHAPPPHMQPQPLHPQPQPQPPYPQGPHPHQPPYPHAPHPQHPQPPPHHPQHLQQPQPPGPHPPRPQQPHPQHQQHPQHQQHPQHPQHPQHPQHPQHPHPGIPPQQQQQHPHLQHPHGPPPQQGPHPPQPMPHPQQHPHHPPHPGPQGPHPRHPPPHHRGPGRGQP------------------------------------------------HPGHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7K9-1", "uniprot_id": "ERC_DROME", "id": "A0A0B4K7K9-1", "name": "Protein bruchpilot", "aln": "MSRDDYNPVTSSGVRSPGRVRRLQELPTVDRSPSRDYGAPRGSPLAMGSPYYRDMDEPTSPAGAGHHRSRSASRPPMAHAMDYPRTRYQSLDRGGLVDPHDREFIPIREPRDRSRDRSLERGLYLEDELYGRSARQSPSAMGGYNTGMGPTS--DRAYLGDLQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQ---------KQAMLVRQLEEELRLRMRQPNLEMQQ-------------------QMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQMYNNYTGASGSSPPLPDIIGQYYGPGSLGPGPLSYGSGNGYGPPGYDLYGPSTSTAAGGYGLYDPQIYGPCQQTSPIRRRRYSIAGLPSATMYNDVYGYPAPPLQQTSSSNIVNLLNEAHKSISRSSQILNLTNQARQLGQLVTTPLGGGGVGMGLGRVVSSYPTLHPGDTSPPYLNDNLMQMSTSFSSQPNMYFQPQAQVQQVLPTQLTAAQSAAAAAARLRPAYSVTNLVSSYPTTTAAGYGCKYGGYGNPYQSDLGYGNPLAPFQQRQLMAHQSLHASNPAISQYYQNQGAATGTGASAAALAYNLQQQFAGTQHYGGGSQGPPLGHSHIQASVQQQMHPQYQYHVHQHQNHLQTHPLAALANTSGPFGGTLASSARDYVDGLHHAAHSHTHPHSHPHHSSHHSHHTAYPHSHSHHQQQQPHQAHHHHHLPYSKLDLDYPKLPQEHKRQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAKVKQAQTQQQQQQDAGPAGFLKSFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . **.* ** . * :.: : .. ::. :.:: . :.:*. : .:.. :. : **: :*.*. :. .. .: .. : : . .: : . : : . . : :** * ::*** *::**::.:.***** :***:********** :****:*: *::::*::: *** : : :: *::*** : :* *: ::. : **:*: :*: :**:*::::* *:******* **************:* ***. : ...: .. : **. .:.: . **: . :.. :*.::* : . ::*:. :.* * : :: *: * ::: ::.:* .: **. . ... :: :.**:. : : *::: *:.:::.*:**: :*::**.:*:.* ::** ****** ***:: :***:*: :* *****: :::***: : .:*:. *:.*: ::** :::*:***.***:*****:: *::**:*: : *:.::*:. *.:: **::****:.:**: : :*::**:* ::*: ** : ..:* * * *:.: : *: : :: * . . * :*:* . : :*: . * .: .:: : *::* . .: .. : .:* . ::...**. *: * *: .:.: : :: *:. : : *:: :: *:::: : *:. :. *: *: .*** : * : : ::.* : : :* .:: ** : *:* * * *: * :::* : **: .. :*:: *: *:* : : : *: ::..:: : ::*: : . : : .: . * . * : *..* : : .:* * ", "identical_positions": 231, "similar_positions": 365, "identity": "10.19%" }, { "cls_id": "homologset.agr.HGNC:31923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Y9-1", "uniprot_id": "LCA5_RAT", "id": "Q5U2Y9-1", "name": "Lebercilin", "aln": "------------------------------------------MGERDQSSDTDQERKGGKHPYSS-------HYSSDFGSSPQSSGPSSPVN--TPPCASNREKNPKRHLSDHHVRHQTVRKVSPKAIPNKKGVRVGFRSQSLNREPLRKDPDIVTKRVLSARLLKITELQNEVSELQVKLAQLLKENKALKSLQYRQEKALSKFEDAENEISQLIHRHNGEITALKERLRKSQEKERMAEKRVKDTEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDNTERKIKELSKNLELSTNSFQRQLLAERKRAFEAHDENKILQKELQRLHHKLKEKEKELDIKNIYANRLPKSSPKKEKEIAR-KHASCQSDFTDLCTKAVQTAEDFEPEEFPFTAQTVLCYENRWDGSEYLPSYLEYQERNEHGSE-SLSSTLEQEGKYSDDQDSCTAKQETGKSECEWERE-------ELDK-VKGKSSLLGRTEKLVLEAGSVQTESYQAQTIDKFQ-DEAERLKTEMLLAKLNEINKELQDP--------QSLSRPLLPLLPNFESKLYSPDR---SLRPYTFSESLDRSFNGQHLSDMSFLTPRDEG------QSPGLIRSPAPSD--EFSFGSYVPSFGKTPGKSNPPSQKNSLLDFQSNMSEGLSKDSLDFISRK-EKKATLMEQLFGTSASASATNTSASTTTNTTTNTNTNTNTNTNTNCNVPSKSIDSHFPAASRGDLDPLHFLSGDRSSRVREPDGEDEDLFLSEGRSFNPNRHRLKHTSTKPTVTAVDSIDEDIEEVTLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ST9-1", "uniprot_id": "LCA5_MOUSE", "id": "Q80ST9-1", "name": "Lebercilin", "aln": "------------------------------------------MGERARSPDIEQGKKGGKHPYS--------HYSSDLGSSPQSSGPSSPVN--TTPCASTREKNPKRHLSDNQVHHPTVRKVSPKAVPSKKGIRVGFRSQSLNREPLRKDPDIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVLQKELQRLHHKLKEKEKELDIKNIYANRLPKSSPKKEKEIER-KHVSCQSDFTDQCTKGVQTAEDFELEDFPFTAQTVLCYENRWDEPEYLSSYLEYQDLNKHGSE-MLSSVLGQEGKYDEDEDPCSAKQEARKPESEWARE-------ELDK-VKGKSALLGRAEKLALEAGRFPTENYQAQSVDKFE-DEAERLKTEMLLAKLNEINKELQDP--------QNLGRAPLPLLPNFESKLHSPDR---STRPYSFPESLDRSFNGQHLQDLSFLTPRGEGGSPGPIRSPGQIRSPAPLD--EFSFGSYVPSFGKTLGKSNPPSQKSSLLDFQSNSSESPSKDSLDLMSRK-EKKATLMEQLFGPSAS----------------------------NTSVSSKSTDPHFPAASRGDMDPLHFLSGDRNSRVREPGDEEEDLFLREGRSFNPNRHRLKHASNKPTVTAVDSVDEDIEEVTLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VQ0-1", "uniprot_id": "LCA5_HUMAN", "id": "Q86VQ0-1", "name": "Lebercilin", "aln": "------------------------------------------MGERAGSPGTDQERKAGKHHYS---------YLSDFET-PQSSGRSSLVS--SSP-ASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWERE-------ELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDS--------RNLKYPVLPLLPDFESKLHSPER---SPKTYRFSESSERLFNGHHLQDISFSTPKGEG------QNSGNVRSPASPN--EFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRK-EKKANLMEQLFGASGS-----------------------------STISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQE-HDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QG33-1", "uniprot_id": "LCA5_DANRE", "id": "E9QG33-1", "name": "Lebercilin", "aln": "MDLHEDNQESEHSRLSHHNERKILESLRSGKQENNGKDMGNSAGDHAQSRTRETAGDPGRNGFSDGERSSGSFYSDDYENASHSDRSLSPSASPSPPRRGRSRRVSSSPLHKTGVHKGASRRILSHSHHPQQ-RAGAIRSQSLSKDAPSKEVDQVTKRMLSARLLKINELKNALSELRLHADELQRENRLLRQLQLRQEKALHRYNDTDSEISQLLARHNNETHVLRERLRRSQENQRTAERSLRERDAQLQRCRSQMQKLQQLADDQNLGEREELSRKLIGTQSRLQDSEHRVKELEKNMELSSGSFQRQLANERRKTHDAQQEVKALQEEVERLCTKLKEKERELDARNIYANRMHKASSRKEAENGS-----KRKGFNITSTKAVQTEDRTSSLDFPSPPPALTNNLPPDDQTDDYLSLKDQQSREHRTRESKEWKIQEFWREREKERHMESAREQEKEKETLHERERQTELLKDVERQRLDQDLSSNEKNFKGNRVGLNREEEDRRIGMSVSQKEEEIQKQRELEEEQQKVRNREIQDYNQERVEEERQRKEQLLAKMREIDIQTQGQDSDFFSDDTGSVRSPPRLSEQRNHNGFFKLTEPDENINTFSSGRRGGSLRAQAPNEDLDLAFGSYAPSFGKSTPRAGLGTRN------AQNHSPRELDEGLDLGGLVKERKSNLMQQLFGATAT---------------------------------------PPPSDPSSKMEILSPPLTTQFSGRRRDTDTPNELNIS---SLPNNRSTLQVSESRPAVRAITSFDDDIEELTL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVD0-1", "uniprot_id": "Q9VVD0_DROME", "id": "Q9VVD0-1", "name": "Lebercilin domain-containing protein", "aln": "-----------------------------------------------------------------------------MVSPRKLASSYGPRVSQSEPNNLMAASAKSCESLFSASSRESASLIYQRSKPPPPQQRGGVKG---SGSMSSQNHSEIHQRVMSARNLRAKTFQNQLADAQAEIANLAHENRMLRTLHNRQSSALNKYEAHNAELPKLLSSHAEELRMWQTKYRKLQAANKALELKLKQKEEIILTLSDQNKHYSQLNKDKNLDERQKLQEKLKSLEQRLEEKDNDMKLMARKVQLESKNIRQQLLNEQRKGKEVMLKLEKAKLEIS--------GYRKLEEYTLGTDKVNPLSSGRRTKLSG---VTDEPDKIDKLEKSMEMLDKAIEKNNQSEFTALTDVME----SESFYDFEKDSAEDKSGPNTPPSQIERQVGGRGGKLILPPATNHAKMGQKANRST---------------LSQVLSAQGKISVSSGKSAKSRIAVAVPKMESVQVSKRREPETVSRLASAETKPKQKP---------------LEYEYEDDYEPAGEDG---DDDAYGMMSKMCEGEEPQDNSEENANE-------------SSLLKYSAYMDNKSSEGDPLEESMEEYDGTDG-------------QQSQGSDDEDISVRAPRLKENMSSLRKQISNDFK-------------------------------------------ERESFLKTFCRQASNSNMRDDSASKKRNSIATG-----AAASSHMTGSRKNALLAALKTIDDNKSQD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * . : : :. ..:. . . :: . : :*::*** *: . ::* ::: : . :* :**: *: *: **..** ::: : *:.:*: * * : : *: * :: * ::: : : . :: .:: . ::* **:.* .** . : :*::.:. :* : ::::*.: .:::** *::: :. : : : *:. ::*: .: :::: *. :. : . . *.:: : : :: . . . :. . . :. : * . . : : : * . : *. * : : : . : . . . . : :. . . :: * : . .. *: : . : .:.:.. :.: . :.: :. . . :. : : : : : .. : * :.::: .: ", "identical_positions": 46, "similar_positions": 196, "identity": "5.69%" }, { "cls_id": "homologset.agr.HGNC:31926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F172-1", "uniprot_id": "F7F172_RAT", "id": "F7F172-1", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "aln": "----------------MLR---------------------YPYFCRTYN-----RLFSYFVDSGAFN-LDVCP--HTIHTTAAMHTEYKASEGIALCDTQKVYRSEETDSEAMAK--LHIPVMVDEVVQCLTPQKGQVFLDMTFGSGGHSKAILQKEPDVTVYALDRDPVAFTLAERLS--EMYPTQIHAMLGQFSQAETLLMKAGVQPGTVDGVLLDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDMPTAADVVNALDQQALASILRAYGEEKHAKKIASAIIQAR-STYPISRTQQLASIVAGAFPPSAIYARKDLLQRSTHIATKTFQALRIFVNNELNELYTGLRTAQKFLKPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVRQT-SQMDSDHEIEERRCVRAPLKWELIHKKVLTPEDQDVQANPRGRSAKLRAAIKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCL4-1", "uniprot_id": "MET15_MOUSE", "id": "Q9DCL4-1", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "aln": "----------------MLR---------------------YPYFYRTYN-----RLFSHFVDSGASN-LDVCP--HTIHTAVALHTESKAVEGTALCGPQKVYSSEEKELEAMAK--LHIPVMVDQVVHCLAPQKGQVFLDMTFGSGGHTRAILQKEPDVMVYALDRDPVAYAIAEQLS--RLYPTQIQALLGQFSQAEALLMKAGVQPGTIDGILMDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDTPTASDVVNALDQQALASILRAYGEEKHAKKIASAIIQAR-STYPISRTQQLASIVAGAFPPSAVYARKDLLQRSTHIATKTFQALRIFVNNELNELYAGLRTAEKFLKTGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVKQT-SQLDSDQETEERHSVRAPLKWELIHKKVLTPEDQDVQDNPRGRSAKLRAAIKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7V9-1", "uniprot_id": "ME15P_HUMAN", "id": "P0C7V9-1", "name": "Putative methyltransferase-like protein 15P1", "aln": "----------------MLR---------------------YPYFCRMYK-----ECLSCWLESGIPN-LGVWP--KRIHTTAEKYREYEAREQTDQTQVQELHRSQDRDFETMAK--LHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLS--ELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGSSLRKDGPLDIRMDGGRN-----------------ISSLCYLY-------------------------TERLTTAIY-------LYCHQDFPG-SSHICEQ-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FZ98-1", "uniprot_id": "A0AC58FZ98_DANRE", "id": "A0AC58FZ98-1", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "aln": "MTYDAATEWTESIESRMMKNLIYGGYMGWNKARNVSYIEHYDFYAIRYSRIYMPQYYSCFMAAPCRQTLGVWKHVATLRNPRMFRRCWRKSWHPGRLYTGSVPSSPDCEMPVQEEKPFHTPVMVKEVLQFLNIKPGQIVLDLTFGAGGHSKAILQSVPGVTVVAADRDPTAFRMAQQLA--EEYQGKVKPVLGRFSELNNLLPALGLGPGTVDAALLDAGCSSMQMDSAERGFSLSKDGPLDMRMDGDRYPDMPCAADVVNALDQQALASVLAAYGEERHTRKIAAAIAQAR-SVYPIGRTLQLASIVAGAFPASALYARRDRLQRPSHVATKTFQALRIFVNDELNELHAGLRVAQTLLRPKGRLCVLTFHSLEDRLTKRFLRGEDLAAPPRRSLRQHARARPAGQEEEFEEEEEGDEGGNSVHWVSLKKVIKPSEEEVQENPRARSAKLRTAVRQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGY5-1", "uniprot_id": "MET15_DROME", "id": "Q9VGY5-1", "name": "Probable methyltransferase-like protein 15 homolog", "aln": "----------------MKR----------------------------------------------------------LLNPTRLRLDWLRRSSIDVTTAP------------------HVPVLCDTAIEYLQPVPGGTYFDMTFGAGGHTRRLLEKCPEAKVYALDRDPLAHQLARDMSESEEFKGRLIPLLGKFSDLPKLFKEHGLAKNSVDGMLFDFGCSSMQFDEAVRGFSISRDGPLDMRMDGGHSGG-VTAADVLANVEEGDLVKILRMYGEEKAAKKIARGLVDARNALFKIETTKQLADIIENIMDGG---TRKDKLRRPAHSATKTFQAIRIFVNNELNEINYGMVLANEILRVDGRLVTITFHSLEDTIVKRHINGNVLAGAANALPLKYSSHYAIDEPDILESLTKKS------WKQLHRHVIVPDADEVARNTRSRSAKLRAAVKTN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : .. * **: . .:. * * :*:***:***:: :*:. . : * **** *. :*. :: . : :: .:**:**: *: *: .:.*. *:* ******:* . ** *: :*****:****.: : .: * * :*: : ::* .:* . : ", "identical_positions": 54, "similar_positions": 58, "identity": "11.79%" }, { "cls_id": "homologset.agr.HGNC:31927", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESG2-1", "uniprot_id": "ROP1_MOUSE", "id": "Q9ESG2-1", "name": "Ropporin-1", "aln": "MPQTDKQVCIPPELPELLKQFTKDAIRTQPPDLIQWAAEYFGAMSRGEIPPVRERSEQIPLSNWAELTPELLKVLHSRVAGRLIIHADELAQMWKVLNLPTDLFNSVMNVGRFTEEIEWLKFLALACSSLGVTIAKTLKIVCEVLSSDHDGGPPRIPFSTFQFLYTYIAEVDGEISSSHVSRMLNYIEQEVIGPDGLIKVNDFTQNPRVRLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLL5-1", "uniprot_id": "ROP1_RAT", "id": "Q4KLL5-1", "name": "Ropporin-1", "aln": "MPQTDKQVCIPPELPELLKQFTKAAIRTQPPDLIQWAAEYFGAMSRGEIPPVRERSEQVPLSNWAELTPELLKVLHSRVGGRLIIHADELAQMWKVLNLPTDLFNSVMNVGRFTEEIEWLKFLALACSSLGVTIAKTLKIVCEVLSCDHDGGPPRIPFSTFQFLYTYIAEVDGEISSSHVTRMLNYIEQEVIGPDGLIKVNDFTQNPRVRLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZX4-1", "uniprot_id": "ROP1B_HUMAN", "id": "Q9BZX4-1", "name": "Ropporin-1B", "aln": "MAQTDKPTCIPPELPKMLKEFAKAAIRAQPQDLIQWGADYFEALSRGETPPVRERSERVALCNWAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGLPRIPFSTFQFLYTYIAEVDGEICASHVSRMLNYIEQEVIGPDGLITVNDFTQNPRVWLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**** .*******::**:*:* ***:** *****.*:** *:**** ********::.*.***********:***:*.*****:*:********:*******************************:*****:***********.**:** **********************.:***:*****************.********** **", "identical_positions": 177, "similar_positions": 28, "identity": "83.49%" }, { "cls_id": "homologset.agr.HGNC:31928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0G8-1", "uniprot_id": "A0A8I6A0G8_RAT", "id": "A0A8I6A0G8-1", "name": "Neurobeachin-like protein 2", "aln": "MAASERLYELWLLYYAQKDLGYLQQWLKAFVGVFEKTISLSSLEP------RRPEEAGAEVPLLPLDALHVLAEQLDQD--NLEQA-----------LLLLKLFIILCRNLENVEAGWGQVLVPRVLALLTGLMAELKGSPPSQEDRSTQLENVALHALLLCEGLFDPYQTWRRQHSGEAISSKEKSKYKFPPAALPCEFGAFFQESLQDAEHLPPTLLLR-LIHLFGAVLAGGKENGQMAVSSGSVQGLLG----VLRGWGRGPAQ------DPHKMQLALRALVGAVHVLHASRAPPRGPE---LRTLLEGYFHILNADWPASPSSS----PEEALVALRVSMLDAIPMMLACEDRPVLQATFLSNN--------CFEHLIRLIQNSKLYLQ-ARAPPE--GDSDLATRLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSGSPSAKEVFKERIGYQHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMHPPPPIRNEQPVLVLTQWLPALPTAELRLFLAQRLWWLCDSCPASRATCVQAGLVSYLLETLNTG-TALGARCQEQLFALLQALGRVSLRPLELRRLLRPPPGLDSESCGTESQKAQHAGAIIRALSGMAR-HRGPARALRYFDLTPSMAGIMVPPVQRWPGPGFTFHAWLCLQSTEAAP--------------TSAPSRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYMTLSLPEVSFADSAWHSVAIVHVPGRRPFSQNLVNVFKDGHLVKTAPLRFPSLSEPFSSCCIGSAGHRTTTTTTG----LPVSSVS----TALSHT-HPSLTRSQSVPASTGLGWGPGLGAPPQEGSISSTLAGTQDTRWGSPTSLEGELGTVAIFHEALQASALRILCILGPNEPAPFKPEGELHELGAKLLLHYSPQACKNNICLDLSPGHGLDGRLTGHRVETWDVKDVVNCVGGMGALLPLLERVAVQPQEAEAGP---CETHDLVGPELTSGHNTQGLLLPLGKSSEERMERNAVAAFLLMLRNFLQGHTVNQESLVQCQGPAIIGALLRKVPSWAMDMNVLMSAQLLMEQVA---ADSSGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSIIREHRQKLRKKYGVQFILDALRTHYSPQRERPLAADDLRTVQTSLLGLVREFLVRNLSVDDMQV---VLSFLAAANEDCQVVGTLDLLLALLQGSPAQEPLAIFLLEPGNLEVLLTLLVRPKSTPLLSDRVCKILRRLQQNERLPERNRQRLRLHDCG-----LQGLVASLPEGIASPQLCQGLYKLFVGTVPQVVSPDCLNLSDLLAVVQLSLQADLSVRLDICRQLFHLIYGQPDVVRLLARQAGWQDVLTRLYVLEATATDSGPPRFVPELPTS---------------------------------------------------SELALSPPPTELPAESSDVFLPSESPCPDPDAFYHALSPFSMPFDLGLERASVDSGNTAGGS-------SSNGTITPAS-QPGTPSPLDGPRPFPTTQGRHSSSLSNVLEDGSLLEPTISGDDTSNT------SNPQQTPEEELCNLLTNVLFSVTWRGVEGSDEAAWRERGQVFSVLTQLGASAMLVRSPDCIKRSLLEMMLESALTDIKEAPPGGLANLSQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCNLLDRLGAWPHLAN--SIADLREMAQIGLRLVLGYILLE-DPQLHAQAYVKLHTLLQTAVPTRREEACYVLSKLEAALSRALTASSSE---TEH--------SCAAMAASERCSWLVPLVRTLLDRAYGPLGLQWGLPSLPPTNGSPTFFEDFQAFCATPEWRHFIDKQVQPTMSKFEMDTYAKSHDLMSGFWNACYDTLMSSGQRLQRDRIQSRRAFQVCSPAWGTVPPHLHGWRQLVGQGREWVGETAASGIDLFLPPQELVLEPAQRRARLEGLRYASVLKQQAAQHSTALLHWGALWRQLSSPCGAWALRVPPTPHWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEAPMTPTEEASLPLAVTKEAKISAPPEELLEDQLGEEELAVLETLMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQHVYFYDGSTERVETEEGIGHDFRRPLAQLREVHLRRFNLRRSALELFFIDQSNYFLNFPHKVAGASASPPCQAPRPQLYPIPPHTQVRNQVYSLLLRLRPPTQGYLSSRSPQEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPVLDLNNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQKHRRALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVADERERKALEGIISNFGQTPCQLLKEPHPPRLSAEEAAIRLARLDTHSPSIFQNLDQLKAFFAEVVSEGVPLLLALVPHRQTHSFITQSASDMLVTVSASGLLGTHSWLPYDRNINNYFSFSKDPTMGNPKVQKLLSGPWAPGSGVRGQALAVAPDGKLLFSGGHWDGSLRVTLLSRGRLLSQLSRHLDVVTCLALDTCGIYLISGSRDTTCMVWRLLQ--QNGLSAG------------------------LAPKPVQVLYGHEAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLP-GPISHLALGSEGQIVVQSSACERPGAQVTYSLHLYSVNGRLRASLTLTEQPTALTVAEDFVLLGTAQCSLHILHLNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIVVGAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPGEAR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQA0-1", "uniprot_id": "NBEL2_MOUSE", "id": "Q6ZQA0-1", "name": "Neurobeachin-like protein 2", "aln": "MAASERLYELWLLYYAQKDLGYLQQWLKAFVGVFEKTISLSSLEP------RRPEEAGAEVPLLPLDALHALAEQLDQD--DLDQA-----------LLLLKLFIILCRNLENVEAGWGQVLVPRVLALLTVLMAELKGS--SQESHGTQLENVALHALLLCEGLFDPYQTWRRQLTGEVISSKEKSKYKFPPAALPCEFGAFFQENLQDAERLPPTLLLR-LIHLFGAILAGGKANGQMAVSAGSVQGLLG----VVRGWGRGPAQ------DPQQVPLALRALVGAVHVLHASRAPPRGPE---LRTLLEGYFHILNADWPTSPSSS----PEEALVTLRVSMLDAIPMMLACEDRPVLQATFLSNN--------CFEHLIRLIQNSKLYLQ-ARAPPE--GDSDLATWLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSGSPSAKEVFKERIGYQHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMHPPPPIRNEQPVLVLMQWLPALPTAELRLFLAQRLWWLCDSCPASRTTCVQAGLVGYLLETLNTG-TALGARCQEQLLALLQALGRVSLRPLELRRLLRPPPGLDSESSGNESQKARHAGAVIRALSGMAR-HRGPARALRYFDLTPSMAGIMVPPVQRWPGAGFTFHAWLCLQSSEAVP--------------TSAPSRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYVTVNLPEVSFADSAWHCVAIVHVPGRRPFSQNLVNVFKDGHLVKTVPFRFPSLSEPFSSCCIGSAGHRTTTTTTG----LPASSVS----TALAHT-HPSLTRSQSVPASTGLGWGPGLGTPLQEGSVSSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQPSALRVLCSLGPNEPAPFKPEGELHEFGTKLLLHYSPQACKNNICLDLSPGHGLDGRLTGHRVETWDVKDVVNCVGGMGVLLPLLERVAVQPQEAEAGP---CETHDLVGPELTSGRNTQGLLLPLGKSSEDRMERNAVAAFLLMLRNFLQNHTVNQESLVQCQGPAIIGALLRKVPSSAMDMNVLMSAQLLMEQAA---ADGGGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSMVREHRQKLRKKYGVQFLLDALRTHYSPQRERPLAADDLRTVQTSLLGLVREFLVRNFSVEDMQV---VLNFLAATGDDGQVVGTLELLLTLLQGSPVQDPLAAFLLELGNLEVLLALLVRPKSTPLLTDRVCKILRRLQQNERLPERNRQRIRLHDCG-----LQGLVASLSEESISPQLCQGLYKLFVG-------TDCLNLSDLLAVVQLSLQADLSVRLDICRQLFYLIYGQPDVVRLLARQAGWQDVLTRLYVLEA-ATDSSPPRFLPELPIS---------------------------------------------------SELALSPPPTELPADSSDVFLPSESPCPDQDAFYQALSPFSTPFDLGLERASIGSGNTAGGG-------SSNGTVTPAS-QPGTPSPLDGPRPFPTAQGRHSSSLSNVLEDGSLLEPNISGDDTSNT------SNPQQTPEEELCNLLTNVLFSVTWRGVEGSAEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPPGGLANLSQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCNLLDRLGAWPHLAN--STADLREMAQIGLRLVLGYILLE-DPQLHAQAYVKLHTLLQTAVPTRREEACYVLSKLEAALSRALTTSSSE---TEH--------ASTAVAASERCSWLVPLVRTLLDRAYGPLGLQWGLPSLPPTNGSPTFFEDFQAFCATAEWRHFIDKQVQPTMSKFEMDTYAKSHDLMSGFWNACYDTLMSSGQRHQRDRIQSRRAFK------------------------------------------ELVLEPAQRRARVEGLRYASVLKQQAAQHSTALLHWGALWRQLSSPCGAWALRIPPAPHWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEAPMTPTEETSLPLAVTKEAKISAPPEELPEEQLGEEDLAALESLMEAAELDEKREKLVLSAECQLVTVVAVVPGLLEITTQHVYFYDGSTERVETEEGIGHDFRRPLAQLREVHLRRFNLRRSALELFFIDQSNYFLNFPHKVAASSASSPCQAPRPQLYPIPSHTQLRNQVYSLLLRLRPPTQGYLSSRSPLEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPVLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWAGSPEDFIQKHRQALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVADERERKALEGIISNFGQTPCQLLKEPHPPRLSAEEAANRLARLDTNSPSIFQNLNQLKAFFAEVVSEAVPLVLALVPHRQSHSFITQSSSDMLVTVSASGLLGTHTWLPYDRNINNYFTFSKDPTMGSPKVQKLLSGPWVSDSGVSAQALAVAPDGKLLFSGGHWDGSLRVTSLPRGRLLNQLSRHLDIVTCLALDTCGIYLISGSRDTTCMVWRLLQ--QSGLSAG------------------------LAPKPVQVLYGHVAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLP-GPISHLALGAEGQIVVQSSACERPGAQVTYSLHLYSVNGRLRASVTLTEQPTALTVAEDFVLLGTAQCSLHILHLNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIVVGAGQPSEVRSSQFARRLWRSSRRISQVSSGETEYNPGEAR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNJ1-1", "uniprot_id": "NBEL2_HUMAN", "id": "Q6ZNJ1-1", "name": "Neurobeachin-like protein 2", "aln": "MAASERLYELWLLYYAQKDLGYLQQWLKAFVGAFKKSISLSSLEP------RRPEEAGAEVPLLPLDELHVLAEQLHQA--DLEQA-----------LLLLKLFIILCRNLENIEAGRGQVLVPRVLALLTKLVAELKGCP-PPQGRGTQLENVALHALLLCEGLFDPYQTWRRQRSGEVISSKEKSKYKFPPAALPQEFSAFFQESLQNADHLPPILLLR-LIHLFCAVLAGGKENGQMAVSDGSVKGLLS----VVRGWSRGPAP------DPCLVPLALEALVGAVHVLHASRAPPRGPE---LRALLESYFHVLNADWPAGLSSG----PEEALVTLRVSMLDAIPMMLACEDRPVLQATFLSNN--------CFEHLTRLIQNSKLYLQ-SRAPPE--GDSDLATRLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSDSPSAKEVFKERIGYPHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMCPPPPIRNEQPVLVLAQWLPSLPTAELRLFLAQRLRWLCDSCPASRATCVQAGLVGCLLETLSTG-LALEARCQEQLLALLQALGRVSIRPMELRHLLRPRPGLDSEPGGAEAGKARHAGAVIRTLSGMAR-HQGPARALRYFDLTPSMAGIMVPPVQRWPGPGFTFHAWLCLHPMDTAP--------------TPAPTRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYLTMSLPEVSFADSAWHCVAIVHVPGRRPFSQNLVHVYKDGHLVKTAPLRCPSLSEPFSSCCIGSAGYRTTTTTTG----LPTPPVP----ATLAYT-HPALTRSQSVPASTGLGWGSGLVAPLQEGSIDSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQATALRTLCTLGPNETAPFKPEGELHELSTRLLLHYSPQACKNNICLDLSPSHGLDGRLTGHRVETWDVKDVVNCVGGMGALLPLLERVAAQPKEAEAGP---AETHDLVGPELTSGHNTQGLVLPLGKSSEERMERNAVAAFLLMLRNFLQGHMVNQESLVQCQGPAIIGALLRKVPSWAMDMNVLMSAQLLMEQVA---AEGSGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSIVREHRQKLRKKYGVQFILDALRTHYSPQRERPLAADDLRTVQTSLLGLAREFLVRSLSADDVQVTQTMLSFLAATGDDGQAVGALDLLLALLHGSLVQESLAVFLLEPGNLEVLLALLVRPGSLPLLPDRVCKILRRLQQNERLPERSRQRLRLRECG-----LQGLVACLPEGTVSPQLCQGLYKLFLG-------ADCLNLSDLLAVVQLSLQADLSVRLDICRQLFHLIYGQPDVVRLLARQAGWQDVLTRLYVLEA-ATAGSPPPSSPESPTS---------------------------------------------------PKPAPPKPPTESPAEPSDVFLPSEAPCPDPDGFYHALSPFCTPFDLGLERSSVGSGNTAGGG-------GSSGTLTPAS-QPGTPSPLDGPRPFPAAPGRHSSSLSNVLEDGSLPEPTISGDDTSNT------SNPQQTSEEELCNLLTNVLFSVTWRGVEGSDEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPVGVLASLTQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCSLLDRLGAWPHLAN--GTADLREMAQIGLRLVLGYILLE-DPQLHAQAYVRLHMLLQTAVPARREEACYVLSKLEAALGRVLNTSSLE---SATDEAGSPLAAAAAAAAAERCSWLVPLVRTLLDRAYEPLGLQWGLPSLPPTNGSPTFFEDFQAFCATPEWRHFIDKQVQPTMSQFEMDTYAKSHDLMSGFWNACYDMLMSSGQRRQWERAQSRRAFQ------------------------------------------ELVLEPAQRRARLEGLRYTAVLKQQATQHSMALLHWGALWRQLASPCGAWALRDTPIPRWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEVPLTPTEEASLPLAVTKEAKVSTPPELLQEDQLGEDELAELETPMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQNVYFYDGSTERVETEEGIGYDFRRPLAQLREVHLRRFNLRRSALELFFIDQANYFLNFPCKVGTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPPSQGYLSSRSPQEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEEAAHRLARLDTNSPSIFQHLDELKAFFAEVVSDGVPLVLALVPHRQPHSFITQGSPDLLVTVSASGLLGTHSWLPYDRNISNYFSFSKDPTMGSHKTQRLLSGPWVPGSGVSGQALAVAPDGKLLFSGGHWDGSLRVTALPRGKLLSQLSCHLDVVTCLALDTCGIYLISGSRDTTCMVWRLLH--QGGLSVG------------------------LAPKPVQVLYGHGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLGATFP-GPIFHLALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASLPLAEQPTALTVTEDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERSHVLVGLEDGKLIVVVAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPTEAR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAW3-1", "uniprot_id": "NBEL2_DANRE", "id": "E7FAW3-1", "name": "Neurobeachin-like protein 2", "aln": "MASKERLYELWMLYYTKKDVVYLQQWLEAFVASFEKVIDVHSIEP------RRLEEWSADVPLLPKEVLVFLSTQLWHS--ALHMSGQDQSITAPHPLLLIKFFIIICRNMENIDSEKTPGFVFETIKLLNFCLAQLKKQP----DDQSTLQAVVQHGLLLCENLFDPYQTWRRRQAGEEVSMLERSKYKFSPLVLPEELPMLFHEYLQDSELIPEPLVVR-LVHLQGAVISGCKRNGLLSITPQAVKDLMS----VLRSWCLCPASSPQQPRDPQLLRMALRCLTVMIHLLHSSSVNERQVE---IRSALDDYFQLLNWNRPPDSQQGDMHAWEDNLITLLEHMLNAIPEILQCSDRPVLQAIFLNNN--------CFEHILRLIQNSKLYQS-NRFKLECEGQCDLTTRLLTESEVEQVWEKGSDCITVHAIRVLTAIMSNSPSAKEVFKERIGYSQLFDVLKSQGQPTKRLLQELMNMAVEGEHSQAMQLGISNEQPLLLLLQWLPDLGSRSLQLLVSQWLAAVCRGTLSCRTVSVEAGLVGSLLEVLSEPPERLDRQCADSLLGLLQDLGSLSLRPCELKSLLK---LLRTEPG---APPHPYCGRVVRVLSAMAARGEGGCSALQYFDLTPPMAGIMVPAIQRWPGSAFAFHAWLCLNTDFPPPQHHYSESHLTNMDNTVRMAKGPRRKQLYSFFTASGTGFEAFFTTEEVLVVAVCTKKEYMAVSLPEHPFNDCAWHSVAIVHVPGRRPFGQNVVTVYVDGVQCKTAPLRFPSLNEPFTSCCIGSAGHRTTTTTMTTSPTLPNPPHSPSEMAFAAHTGPPTLLRSQSFPASFAAAAG-GRPGGNRESPVHTIQAGLQDTAWGSPSSLGGLLATAFICHEALQPAQARALFTAGPNNVSLFKADGEPSEVNSKLVLYYTPKAFKSQICLDLSPNHLYDGRLTGHRVVNWDVKDVLSSVGGMGALLPLLEQVCLLDQRETVG----QETSDLLGPELTSSRGPAGMLLPLGKSSEGRLEKNSVAAFLLMIKNMLRNHPANQESLLQCHGPAIIGAMLGKVPSSMMDMSVLMACQFLLKQVS---NEGNNALLSQLYQYLLFDFRIWSRSHFAVCLGHVQYLTTVINEGKLKTRRKYGVQYILDSIRTHYSVEKDGSPLSDERQTVQISLFSLLKDLLK-SPTAEELHS---VLAYAAIVQDEQQVISVLDVLHTVLKSSPPPREQVVTVLLDRRVEQLYYLLLKTNYGDEARERLFRVMYKVLKSERVHDRNKQLIKLKDSG-----YLGLVCSFGDVPITMTTVRCLYEQVLAT------DPTPSFKDLLAVVYLSHRADLSARLEIVRKLFCLIHSNEEYVKQLAHQSGWQDVLTKLYVKESYESRVRSQSNSLSSPTSSLDPVLSRPVFRRDDSVTEDVRQNVYITLAARHEEEYEEEEGETQDASEGFSDLSQSPPSTGQLKNDSLHFKPFDSGDQSSHSSTLSNTVDFPPSRLQEEDEAVYQPLSPFGSPFELELNHQKGPQTPVGSQPETPSPLEHNKTFLGMRPRKSSSLSNVLDDTSYSTEPPT-DTISNT------SNPQ-APEEELCNLLTNIVFSVLWIGTEGSEDVIWRERGQVFSVLTKLGSSCQLVRPPDDIKRSLLEMMLESSLSDLRDSQ-GVSLPHVPSLLRLLRLLQDFLFAEGTCNHTLWSEKIFEGVVNLLDRLKAWHTTPGSAGSAELKEMSLIGLRIITGYIQQQQNPQVCEMACLKLHSLLQTVLCLSWEEVCFLLGRLGAPLCPANSASDTS---AEG-----------------LPSPLVPIVRALLDQHADHTTLQEKLPNLPATNGSPSFAQDLQIYCSTAEWQQFYQNHVEPTMQQYELDTFGKSHDLMSNFWNSCFDDLMSTGQRRDKERSDSKAKFQ------------------------------------------EVIVDPYLKRVRTENSRYHSVQKMINGQQTVVWRHWRSLRRLLSSDRGAWPLRVQPEVKWKLSSAETYSKMRLKLVPNYSFDSHSDASALRDNMGADSPRSSTEP-LPLAVAREAKVSD----MDDDKLEDEDIVFLEEAEEAEEES-QKEKLVLSEDCELITIVAVVPGRLEVTTHHLYFYDGSSEKEETEEGIGFDFKRPLSQLREVHLRRYNLRRSALELFFIDQSHYFINFR-------------------------KGVRNKVYSRILGLRPPNLFYFGSRSPQELLKASNLTHRWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSAELDLDDPAVFRDLSKPIGVVNPRHAQNVREKYESFEDPTGTIDKFHYGTHYSNAAGVMHYMIRTEPFTSLHIQLQSGKFDCADRQFHSIAAAWQARMESPADVKELIPEFFYFPEFLENMNGFDLGCLQISQEKVNNVLLPPWASSREDFIRKHRKALESEHVSAHLHEWIDLIFGYKQRGPEAVEALNVFYYCTYEGAVDLDAIANETERKALEGIISNFGQTPCQLLKEPHPPRMSAENAFRRAARLDILPPNLFDQLSKLRS-FKEVVSDGLALVQAVVPRNQTRSFIIPGS-DILVTVSANGMIGTHSWLPYDKNIANYFTFTRDPSVSNPKTQRFLSGPFSPGVEMGSQVLVVSSDGRLLFSGGHWDCSLRVTMLGKAKLVGRICRHIDVVTCLALDLCGIYLISGSRDTTCMVWQVLQ--QGGFSSG------------------------LSPRPIQVLCGHDQEVTCVAISTELDMAISGSKDGTVIVHSVRRGQYLWTLRPPCENCVSAPVAQLEVGMEGHIVMQTVLEGRSAGKERYALHVYSVNGTLLASETLDEKISALYLVPDYLIVGTQQGNLHIRDLYSLNLAVAPLALKVPVRCVSVTKESSHILVGLEDGKLIVVGAGKPEEVRSGQFSRRLWGSTRRISQVSSGETEYNPVEAPAK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MRV7-1", "uniprot_id": "M9MRV7_DROME", "id": "M9MRV7-1", "name": "Neurobeachin-like protein 1", "aln": "MDNKKDIYNLWVQYTTKNDETHFRQFVARFVAIWRSQLQLDFQAENCPMWHEVQPDSGPHLGRLPDELLPAIGKFIIVARDVCETEGKLEEQAIEEVAILVDCLVIVCRHFDNILSIIKYEYKPNLIAILSRVFKQQMELP----QSVPAISHLFSSFSAFLEVMYDPYLTWRSFVRG---QSADYSRLSYKPHSVHVEIVPFIYDCFQEEKLIRYAEIGESLLNILGAVICGSQLQLKVQKSLNSTSTLTNRNTNALTTSSLAPCSG-DGLLDCDNLRNGMKAICPATVSITMSILRQWESANNLRRVALQCYALMVIVLQKSSPEER-----QIDLVTLVQLYCDALQELLATKHFDSGDANFDITSDADQDVAIDMAALSSTVAAVKFFVTGDAGVSEAVSDSNLLELLTNLPKLIKPWHISHSSSLCSTMEALAILARHSPQSASQLRQGERIERLFTSLQEYGSPTVELLDTCFMLGYDESEHFLLLP-----EVMLRLLNWVPTLQER-EQLHVTSLVLKGCTDNYRTKTVACGSHIIKAVCGCLLTA-ESLAENCVQNLIKLIEELSKLSIVPAELKCIFS----LLRQGTKFPQFKQLQQTLVVIALQSLRG----SNSCAEFFSIEQPTDGILVPDIRNWTISGSYGFIFHILVRFNQLK------------------EQSNSRRMLLTLQTASGSGFEVFVQPNGNVVVAALTRREYLTSSTATKTLMDGQWHYLTVAITPPKRPFSYSQINIYVDFVQKLSATLKVQAVNEPFTVCSIGAVVAPPQPGEVAKTGNMPRSSSQESGSSGYKGMLPSLLERTLSANVSNYFTLPMRTQTAFDPN-VKNFPIGMQDTVFGEQTCLNGHLGGVLLADP---TTSLKTIFDAGANFSSIFSQDNDLLELNSRFVFCYAPGAIWHGTCQDLIPGGKYPGRINAQHCKIVKIQETINSIGGISAILPMLHRLITLDQTTDISIGSVSEESLSCAPTPSAEEFTDWEMLSSNSYTEWKMLQHPLASFLCLLRYLTHEHETNQEQLLSSECLAIVGTMLQRCPPSLFDVNALMATHLLMESLQGHKAEAGGQLLDALYAHIVFDFAIWSRLQFQITLGHAQYLSAMIKNDRKFFRKRYGVQFVLDVVRQYYSTP--DSISDDDAKTIRATLFGIIKFYLQKDVNIKEVNS---MITFLASVRQDVVLVEFLEMMTFYVRGKNCKDQMVLLLHEPQSANLLYNFFVDKSYSNEIQEAAIRFISGLLATSRVHQKYKQVLRLYDQTTEQSMFPGFFSFITPLSLSSTILFHLVDEMLG--------LQPDYAGLIFLVYHVSSCDLPVKLEIAKRLLQTTFVKQQSTVAMAKQTGWQESIARLLIRKPITSSPPDEEKRRSFGIN----------------------------------LDVLLEDNSNFLAQADLITFSEQEIGLAQLQQQQQEELSDSGLILNEIQASVTEAATVIESEIKELAESVSGAVVENANSLFSVIRQTTHDLQDTFESLTQGSSTDTADGSQTPSIQREESLSSDTSSQSPHGPPKKSDSLESTSAFDFVADGDVDTEEQLVYLVSNTLFNIFWRGIPNDHPQCWQERGQVLGCINLLALNNELITSHLSLRLRILEMAVQASLFDLSEHGSQTLVNQENASHILRMVYELVVLGSNEDESKKCSTKLLDGVLALLDALMIFQQGSS----DDWSDMIRLCLGLLLKCSHHP-NPGIVAMATAKLHAILQSRSTEDPAELSYLLYSINRALDNAIEVGNPEEYS-----------------------FLMPVMKALLEKCRVAFNLDSTLPDLPSTSSGPVFFNDFQMYSTSKKWRNFIERMVKPLYDRYQRDIELHLWEPINRFWAECYEACKAASKQRATNQAENRRLFQ------------------------------------------QKIYMPWKVRQVEEMQRLQAAALQHKTIDSHIRKRWKTAKRFLYGPRGPWYTGEVDEEFWKLSQHENVARMRLKLEPQLYPNKHENAANLRDNA-----TSAYDTKEISEFDSTIKNAVVRDFLADDESSQLEEELRQLIDTQAQQDVALEKLVMSQDCELITLMTKVKGRIEVNQSVFTFVDLSPP---TEDGSKYDFRFSTNKIREVHLRKYNLRRSALEIFLVDQTSYFLNFT-------------------------TKTRNKVFTKIVGLPLPNILYGSGRSPAELLRASGLTQRWINREISNFEYLMYLNTIAGRSYNDLSQYPVFPWILADYTSDVLDLTDPKSFRDLSKPIGCINPKNEAEVRGKYDSFEDPSGAIPKFHYGTHYSNSAGVLHYLLRVEPFTSLHIDLQSGRFDVADRQFHSIPQTWKLLMDNPNDVKELIPEFFYFPEFLKNMNKFDLGHLQITKEKVDDVILPAWATTPEEFIAIHRRALESEYVSQHLHHWIDLIFGYKQKGPKAAEALNVFYYCSYEGAVDLDKITNPVEREAVEGMINNFGQVPSQLLREPHPRRLTQDETALKLVRAELRRPDLTQFLDKVVQYYCELSTPKDPIVYLSPPRSPPRSFLQLSP-DVLVSISKSTILGCNSWLSFDKDQG--FLLEIDATTANLKNRKRIFGPFHSSQQPHSQLFAVSTDGKLLYAGGIWDNSLRVYNLNKGKAVASVTRHLDIITCIALDNCGSYLVTGSRDCTCIVWSIQTNQQGGGSTNNIPVHALTGQSHLQAITQLNTQNSYSPKPLTVLYGHDDAISSVAIYTELDLVVSGSLDGTVNVYTLQEGQFVRTLKPIGCTESCVQISFVTLSYHGHIAFS------ALDDTSHSVHVYSINGCSLGSKYVSGRVTGLASASDYLVVADDAGDITMSRLHGLKPVFD-IPLHVPIQTVVVTPGNTHILAPLRDGRLAVIAVQLPSGGNKKHSVLNV-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: :*:**: * :::* :::*:: **. :.. :.: . : ...: ** : * :. : . :*:. ::*:**:::*: : . : :*. . : . :. : : * ::*** *** * . : *: .: * : *: :: : :*: . : : . *::: *::.* : : : : :.. * . .: *. * : .:..: : * * *: * :: .. .. : *::* :*: :* .. :* * .. : : : *:: * .:.:* * . ..: : . . .. .:..*: : **.: . ::: :* *:. * ** .**: : :. : .. : :* * :*:* * :* ::. : * . ::.. : :: : * * .* :.*: *:: *. :*: * **: :: * : :: .*..: . .:*.: . **:** ::.*. .. . : * : *: * :: *:**:***.*. . :***. *::**:: . . .: * ** :::. .* :***. . : :: * :..:: ::.***: *.**:. . . :* .. : . * *: * .* . : . * *** :*. :.* * *. . : . .: : : *.* : *. :.: *..::::: *:* * * ** *. **:..:: .:::.:..:**:..:**:*.:: : . * .* :: . . :*. .. :* :: ::.:*:** ::: : : * .***.*:... **:*::* : *. :*:..**: ::*::. :... ** ** :::*:* :*: .* : *** **:::::.: : *::****::** :* :** . *: :*:: :*:.: : * . . .::: :: : * . :: : *::: ::.. . : : * ::: : :.: : ..*: :: :* ::* : *:.. : : * . .:. . .*: :* .**..:*:* ::*: . : : . :*:*:***: :::* : :. : . . : : . . .. . : : : :: .. . . . *. : ::..***. .. * . * ..* :: : .**:* *::* :*.: * * .. *:*****:. :. *. . *: . :: :*** ::::* *: : * : : .: ... : * *:::** *** * : .. : :* : * :: :* : * :** :**: * .::* : .* . ... . *:*::::**:: *: **.**.*...* * :*:* :.:: :*::* :. *:* .::: * : : :. ** *:: ::.:: :: :.: *: : : * * * * :. .: :* : * * . *.* ****. *. ::***** *: : * :*: **** .: :. . * : : ::: : : : : . ****:* :*:*:*::: * * :*:. . * * *. **:* .**: . ::******::********:*::**: **:** . **:*:: :: * *. * ..*** *:*:**.**::*: ********** *******:************:* **.* *** :* ********* :**:: ** **:*****:*:* **********:***:**::*.*******::****:** :******:. :*: ::.* *************:**:* * **** **:::***.:*:**.** : *:** **:*****:** ***.**********:** * *********:******** ::: **:*:**:*.****.*.***:**** *:: ::: : .* : *.: : *.:: : *: : .:: *: .:**: .. *:**::* . ::* ::**.:*:: * : *.: .. * :: : **: .. .* :.*:.**:**::** ** **** * :.: : : *:*::**:*** ** **::**** **:** : *.* * . :*:*: ** ** ::.*** ****:.:*** **** :::::.**:: :*:* . : : :. .*:*... . . :::*:**:** .* : : :.* . *::::. : : * * . :.::*.:: * ** :*:*. *.**:* *: . *. .. : .: ", "identical_positions": 665, "similar_positions": 874, "identity": "22.25%" }, { "cls_id": "homologset.agr.HGNC:31930", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9P821-1", "uniprot_id": "ZN574_DANRE", "id": "A0A8M9P821-1", "name": "Zinc finger protein 574", "aln": "MESSSVYMCFPCYREFPTLEEVLAHQMTCTAENPQLLPNETPVEAAAAAAGLPQVAMQAVTVPQIQTQTAVDLSSLLQQKKTIQADAPRVLYQCADCEVLFDALSLWQQHRKMGCCLETEPAGEQTEETYEAVAQPQPSQKENENAVQEQNTPEQTQVKEVVEIRFESVSQGSVEVAGKVAAPATSEEEESSNSVSKEASATHEASSVETSAEASSPATRRRGQKKAKPPSSLLCVECGQSFSLVPELVTHRRTQHGLKDAIHRCAVCGEGFLNTTLFLYHRRQHRSEVEEEPKQASSGIPQISTAMLEAPGEGLLLLATAGEGQSLMEVTTLEQTITETPVAQVEVELEGNEIRGTEQEPMVEGAEILVEKTEEMLEEHEAPDQEVKMELVIEKVEGNVQMEKIGADEEIQDAVESNASENTSTAFLCHQCGSVFSNDQELAKHRKAEHGLEAALHTCGDCGAKFMSTTQFLYHRRQHKNTTAGHLVTAEVKSRLYTTAASGAAAADGGLEAPAKLSREWSRTALPHECPHCGQGFTRRSRLREHVFQHTGEKLFNCKICKKSFPSPANLLRHSLIHGGSRIYSCPICDKRFFQPTSLKRHMMTHQEGVQERRTRGRGKGRGPSSDGRLHICPECPASFKLEAQLKSHRLLHTSHPFPCSVCGEAFIRRKELDLHSLIHQDKEPKMCPNCGSQFLNQTVLDTHLQRCTGEQTGQRKYKGQGRGKVGGQLECDMCGHRCVTQDGLDLHRLSHTGQTPLRCPLAPCRRRFASSAALGEHLVAHCCGALGKRNAPRRFTCEFCGKEFAYASTFTVHMRTHTNERPFECAQCGKRFRQLPHLQDHERIHSGERPFTCWVCGKSFSVAARLTEHARVHSGERPYVCPRCPTAFRSRPNLDKHMRIHANDPVDPTAQNVMDDDAAVQTILLVQESASSSPSSSSSVMPVVQEGMFVTEEGGSSVVFLHPNMSMPTITVPAISVPSMNMPNISVVAGQDVPHTIEVILEETV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6ZS27-1", "uniprot_id": "ZN662_HUMAN", "id": "Q6ZS27-1", "name": "Zinc finger protein 662", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLENYGAVASLAAFPFPKPALISQLERGETPWCSVPRGALDGEAPRGISSGYPFLKPAG---------------------------------------------------ISHPEQVEEPLN-------------LKLQGEGPSLICPEG---------------------------------------------VLKRKKEDFILKEEIIEEAQDLMVLSS--------------------------------------GPQWCGSQELWFGKTCEEKSRLGRWPG--------------YLNGGRMESSTNDIIEVIVKDEMISVEES---SGNTDVNNLLGIHHKILNEQIFYICEECGKCFDQNEDFDQHQKTHNGEKVYGCKECGKAFSFRSHCIAHQRIHSGVKPYECQECAKAFVWKSNLIRHQRIHTG----------------------------------------------EKPFECKECGKGFSQNTSLTQHQRIHTGEKPYTCKECGKSFTRNPALLRHQRMHTGEKP----------------------------------------------------------------------------------YECKDCGKGFMWNSDLSQHQRVHTGDKPHECTDCGKSFFCKAHLIRHQRIHTGERPYKCNDCGKAFSQNSVLIKHQRRHARDKPYNCQIS------------HLLEH--------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * **: *: :.: . * . * .* . : :..:* * **.. .* .:*** : *: *** *:.. * :* .*.*::: :.* :: .: :: . *. :...*** :..*. . . . * . : ::::..:: . **..: :. * :.: .:: : :: . : : * .**: * :.. : :* *.***::.** * *:*. :: : *. **.* : *.* * * *. :.* ** * .:** *. **:.* :...* *. ** .::* * :**..* .:..* * : ***:. : *: *** * : * :: * *.**.::*.**::*** * .** *:***:****:.* ***:** : * :* * *: ::** * . *: * ", "identical_positions": 124, "similar_positions": 151, "identity": "12.33%" }, { "cls_id": "homologset.agr.HGNC:31932", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVR1-1", "uniprot_id": "NTM1B_RAT", "id": "D3ZVR1-1", "name": "N-terminal Xaa-Pro-Lys N-methyltransferase 2", "aln": "MAHLGAHFAFRSRWQKTDDELCRHSMSFILHKAIRNDFFQSYLYLLEKIPLVKLYALTSQVIDGEMQFYARAKLFYQEVPATEEGMMGNFIE---LSNPDIQASREFLRKFVGG--PGRAGTGCALDCGSGIGRVSKHVLLPVFSSVELVDMMESFLLEAQS-YLQVN--ENKVESYHCYSLQEFTPHLGRYDVIWIQWVSGYLTDKDLLAFLSRCRDGLKENGVIILKDNVAREG-CIFDLSDSSVTRDMDILRSLIRKSGLVVLGQEKQEGFPEQCVPVWMFALHSDRHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXM4-1", "uniprot_id": "NTM1B_MOUSE", "id": "B2RXM4-1", "name": "N-terminal Xaa-Pro-Lys N-methyltransferase 2", "aln": "MAHLGAHFAFRSRWQKTDDELCRHSMSFILHKAIRNDFFQSYLYLLEKIPLVKLYALTSQVIDGEMQFYARAKLFYQEVPATEEGMMGNFIE---LSNPDIQASREFLRKFVGG--PGRAGTGCALDCGSGIGRVSKHVLLPVFSSVELVDMMESFLLEAQS-YLQVN--EDKVESYHCYSLQEFTPHLGRYDVIWIQWVSGYLTDKDLLAFLSRCRDGLKENGVIILKDNVAREG-CIFDLSDSSVTRDMDILRSLIRKSGLVVLGQEKQEGFPEQCVPVWMFALHSDRHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VVY1-1", "uniprot_id": "NTM1B_HUMAN", "id": "Q5VVY1-1", "name": "N-terminal Xaa-Pro-Lys N-methyltransferase 2", "aln": "MAHRGAHFAFRSRWQKTDDELCRHSMSFILHKAIRNDFFQSYLYLLEKIPLVKLYALTSQVINGEMQFYARAKLFYQEVPATEEGMMGNFIE---LSSPDIQASQKFLRKFVGG--PGRAGTDCALDCGSGIGRVSKHVLLPVFNSVELVDMMESFLLEAQN-YLQVK--GDKVESYHCYSLQEFTPPFRRYDVIWIQWVSGHLTDKDLLAFLSRCRDGLKENGIIILKDNVAREG-CILDLSDSSVTRDMDILRSLIRKSGLVVLGQEKQDGFPEQCIPVWMFALHSDRHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JM82-1", "uniprot_id": "NTM1B_DANRE", "id": "B8JM82-1", "name": "N-terminal Xaa-Pro-Lys N-methyltransferase 2", "aln": "MEFSGTHQAFRNRWAKTDDEMCKHSMSFHLHKTLRKEFFASYLYLLEQIPLVKLYALTCEYIKGEKQFYYRAQNFYKDVPPSEEGMMGDFVE---ISDIDLEGSRQFLKKFVG---PGKAGTKCALDCGCGIGRVSKGVLFPVFESMEMLDMMEEFILHAHECYLGDY--ADRVESYYLYNLQEFIPPRKKYDVIWMQWVACHLTDKDLMEFLMRAKESLRPNGVIIIKDNMARQG-CKLDPIDSSIIRHLDIMNGIIQRAGLNILDVEKQEGFPEAIVPVWMIAMR-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38340-1", "uniprot_id": "NTM1_YEAST", "id": "P38340-1", "name": "Alpha N-terminal protein methyltransferase 1", "aln": "--------------------------------------MDVPADSHIK--------------------YEDAIDYWTDVDATVDGVLGGYGEGTVVPTMDVLGSNNFLRKLKSRMLPQENNVKYAVDIGAGIGRVSKTMLHKHAAKIDLVEPVKPFIEQMHVELAELK-DKGQIGQIYEVGMQDWTPDAGKYWLIWCQWCVGHLPDAELVAFLKRCIVGLQPNGTIVVKENNTPTDTDDFDETDSSVTRSDAKFRQIFEEAGLKLIASERQRGLPRELYPVRMYALKPMPN-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q6NN40-1", "uniprot_id": "NTM1_DROME", "id": "Q6NN40-1", "name": "Alpha N-terminal protein methyltransferase 1", "aln": "------MTTTLEEQLSDKLQMMDETTDKVQGSSKQKDDSSIAASSDAKTASPSSSDSSTKVAAPESEFYNKAQKYWSEVPATVNGMLGGLGY---ISAIDIQGSNVFLREIR---VPGN---RLALDCGAGIGRVTRNLLIPRFSCVDLVEQDPAFADKAREYCTSEDGSRGKVGQIYNVGLQKFTPTQ-QYDLVWTQWVLGHLTDRDLVSFFRRIKQGLAPGAFLCLKENVSSSKKTVEDRNDSSVTRPLDSYEHFLKEAGFRIVRKVKQQNFPKGLFPVYMIACKPVSKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * :: :* .: :*::*. :. *: .*. **::: * . *:* *.*****:: :* ::::: * . : .:: . : .:*.: * :* ::* ** :*.* :*: *: * .* .. : :*:* : * ***: * . ::..:*: :: :* .:*. ** * * : ", "identical_positions": 46, "similar_positions": 70, "identity": "15.75%" }, { "cls_id": "homologset.agr.HGNC:31940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7R4-1", "uniprot_id": "A0A0G2K7R4_RAT", "id": "A0A0G2K7R4-1", "name": "Olfactory receptor", "aln": "-MDHNNT-VSEFIMLGFTTDPVMQKVLFAVFLIVYTLTLIGNCSLIMLICNDSRLHTPMYFFIGNLSFLDLGLSSVYTPKILATCISEDKSISFAGCVTQFFFSAALDYTECYLLAAMAYDRYVAISKPLLYSQAMSLKLCVFFVAASYLGGFINSVIITKDTFALTFCSDNVIDDFFCDIPPLVKLACGKKDSFQSVLFFLLTSNVIIPIVFILATYLFIIATILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYARPRSSYSLDRDKIVSTFYTVVFPMLNPLIYSLRNKDVKEALNKLLK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TR95-1", "uniprot_id": "Q7TR95_MOUSE", "id": "Q7TR95-1", "name": "Olfactory receptor", "aln": "MEQYNDT-VTEFILVGFTTNPVMQLVLLVIFLAVYALTVLGNSTLIVLICNDSRLHTPMYFFIGNLSFLDLGLSTVYTPKILVTCISEDKSISFSGCVAQFFFSAGLGYTECYLLAAMAYDRYVAISKPLLYSQAMSLKLCAFLVGVSYLGGLINSFIITKDTFALTFCNDNVIDDFFCDIPPLVKLSCGKKKSFQSVLFFLLTSNVIIPIVFILATYLFIIATILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYARPRSSYSLDRDKIVSTFYTVVFPMLNPLIYSLRNKDVKEALSKLFK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ASV2-1", "uniprot_id": "A2ASV2_MOUSE", "id": "A2ASV2-1", "name": "Olfactory receptor", "aln": "MERGNHT-VSEFILLGFTSDPTTQLVLFVMFLIMYTLSVLGNITLIVLICNDSRLHTPMYFFIGNLSFLDLWLSNVYTPKILAICISENKSISFASCVAQFFFSAGLDYSECYLLAAMAYDRYVAISKPLIYSQAISMKLCAFFVAASYMGGFINSSIITKKTFTFDFCNDNVIDDFFCDLLPLVNLACGGKEGYQTLMYFLLTSNVMIPIALILASYIFIIATILRIRSTQGRMKAFSTCSSHLISVTLYYGSILYIYSRPRTRYSLDSDKVVSTFYTVVFPMLNPFIYSLRNKDVKEAMNKLFKIIPL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7N8-1", "uniprot_id": "OR9G9_HUMAN", "id": "P0C7N8-1", "name": "Olfactory receptor 9G9", "aln": "MQRSNHT-VTEFILLGFTTDPGMQLGLFVVFLGVYSLTVVGNSTLIVLICNDSHLHTPMYFVVGNLSFLDLWYSSVYTPKILVICISEDKSISFAGCLCQFFFSAGLAYSECCLLAAMAYDRYVAISKPLLYAQAMSIKLCALLVAVSYCGGFINSSIITKKTFSFNFCCENIIDDFFCDLLPLVKLACGEKGCYKFLMYFLLASNVICPAVLILASYLFIITSVLRISSSQGRLKAFSTCSSHLTSVTLYYGSILYIYALPRSSYSFDMDKIVSTFYTEVLPMLNPMIYSLRNKDVKEALKKLLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LHG2-1", "uniprot_id": "A0ABK0LHG2_RAT", "id": "A0ABK0LHG2-1", "name": "Olfactory receptor", "aln": "MERSNHT-VTDFILLGFSTDPVMEKILFVLFLGVYSMTLIGNTTLIILICNDSRLHTPMYFFIGNLSFLDLWYSSVYTPKILVTCISEDKSISFAGCLAQFFFSAGLAYSECYLLAAMAYDRYTAISNPLLYAQAMSRRLCICLVVYSYTGGFVNAIILTSNTFTLDFCGDNVIDDFFCDVPPLIKLACDVRESYQSVLYFLLASNVISPTLLILTSYLFIIAAILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYSRPSSSYSLERDKMVSTFYTVLFPMLNPMIYSLRNKDVKEALRKLFKLAHAEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFJ7-1", "uniprot_id": "Q8VFJ7_MOUSE", "id": "Q8VFJ7-1", "name": "Olfactory receptor", "aln": "MERGNHT-VTGFILLGFSTDPVMQKILFVMFLGVYSLTLLGNTTLIILICNDSRLHTPMYFFIGNLSFLDLWYSSVYTPKILVTCISEDKSISFAGCLSQFFFSAGLAYSECYLLAAMAYDRYTAISNPLLYAQAMSRRLCVCLVVYSYTGGFVNAIILTSNTFTLDFCGDNVIDDFFCDVPPLVKLACDVRESYQSVLYFLLASNVISPTLLILTSYLFIIAAILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYSRPSSSYSLERDKMVSTFYTVLFPMLNPMIYSLRNKDVKEALRKLFKLAPSEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5Q1-1", "uniprot_id": "A0A0G2K5Q1_RAT", "id": "A0A0G2K5Q1-1", "name": "Olfactory receptor", "aln": "MDEENVTEVTEFILLGFTGDMVLQQVLFFIFLTIYIISLLGNITLISLICSDSRLHTPMYFFIGNLSFLDLWYSSVYAPKILITCISEDKSISFAACLAQFFFSAGLAYSECYLLAAMAYDRYVAIANPLLYSQAMSPRLCASLVAASYLGGFANSTIITSETFTLSFCRDNIIDDFFCDLPPLVKLACDVKESYQAVLYFILASNVITPTVLILASYLFIIAAILKIRSTEGRLKAFSTCGSHLTAVTLYYGSILFIYSRPSTSYALERDKVVSVFYTVVIPMLNPLIYSLRNKDVKEALRKMLDTVKLS-", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *: **::**: : : *: :** :* ::::** :** ***.**:*******.:******** *.**:**** ****:*****:.*: ******.* *:** **********.**::**:*:**:* :** :* ** **: *: *:*..**:: ** :*:*******: **::*:*. : :: :::*:*:***: * :**::*:***:::*:* *::**:******.*** :*********:**: * : *::: **:**.*** ::*****:************: *:: ", "identical_positions": 170, "similar_positions": 84, "identity": "54.49%" }, { "cls_id": "homologset.agr.HGNC:31948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9QA28-1", "uniprot_id": "CEA16_MOUSE", "id": "E9QA28-1", "name": "Cell adhesion molecule CEACAM16", "aln": "MKMPLTWYSWFLLSAWILNTGAEISITPEPAQPAEGDNVTLVVHGLSGELLAYNWYAGPTLSLTFLVASYIVSTGDETPGPAHTGREAVRPDGSLDIHGALPGHTGTYILQTLNRQFQTEVGYGHMQVYEILAPPTVMANDTALVERRDTLRLVCSSPSP-AEVRWFFNGDALPVAVRLGMSPDGRMLTRHGVRREEAGAYQCEVWNPVSVSRSEPLNLTVYFGPERVAILQDSTTRTGCTIKVDFNMSLTLWCVARSCPEPEYVWAFNGKALKNGQDHLNISSMTAAHEGTYTCIAKNSKTLLSGSASVVVKLSAAAVAMMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGNWIAGPAHTGREVGFANCSLLVQKLNLTDAGRYTLKTVTLQGKTDTLEVELQVAPLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQE1-1", "uniprot_id": "CEA16_RAT", "id": "D3ZQE1-1", "name": "Cell adhesion molecule CEACAM16", "aln": "MKMPLTWGSWFLLSAWILNAGAEISITPEPAQPAEGDNVTLVVHGLSGELLAYNWYAGPSISLTFLVASYIVSTGDETPGPAHTGREAVRPDGSLDIHGALPGHTGTYILQTLNRQFQTEVGYGHMQVYEILAPPTVMANDTALVERRDTLRLICSSPSP-AEVRWFFNGDALPVAVRLGLSPDGRMLTRHGVRREEAGAYQCEVWNPVSVSRSEPLNLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWAFNGKALKNGQDHLNISSMSADHEGTYTCIAKNSKTLLSGSASVVVKLSAAAVAMMIVPVPTKPMEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGNWIAGPAHTGREVGFANCSLLVQKLNLTDAGRYTLKTVTLQGKTDTLEVELQVA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2WEN9-1", "uniprot_id": "CEA16_HUMAN", "id": "Q2WEN9-1", "name": "Cell adhesion molecule CEACAM16", "aln": "--MALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAPLG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.** **:**** :**.******* *****:*******************.*****::*:::********************************:* ** *:*******:***:********:**:**** ***:**.************:****** *********.*****:***:*****:*:***:***********************:****************************** *******:**********:***:**************:* :**********:******************** ********* ***************************************.**************.*************:*********:****:********* ", "identical_positions": 372, "similar_positions": 38, "identity": "87.12%" }, { "cls_id": "homologset.agr.HGNC:31949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D871-1", "uniprot_id": "CEA18_MOUSE", "id": "Q9D871-1", "name": "Cell adhesion molecule CEACAM18", "aln": "---------------------------------MDFSRPSFSPWR----------WLTLVASLLTCG--------------------------ICQASGQIFISPDSLLGVEKYR----TILTLENVPEDVLEYSWYRGKDNSTEN----------MIFSYKPPNTRHPGPSYSG-------------------------------------RENVTRAGSLVVRMSAVNDTGYYTVEVDTSNETQRATG---------------WLQIVKLRSNPGISANTSALVEGMDSVVAKCLTNSSNISWYVNFVP---------------TSGSNRMTISPDGKTLIIHRVSRYDHTLQCAIEDVPEILQKSELIQLTVAYGPDYVSLWT--QPYFFAGVLTADIGSSVQLECNCFSKPEPRYHWIHNGSFLSIP-------------------------ENNMTLPSLSWEQMG--SYRCVVE----NPETQLTFYRDVTIQPPRPPLPTVNRELYIPGPLVIFLILLT--------SLGGAFVCRVLVYS---------LFQSCSRGK---------------------TCHKC-----------PWQTN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MTB9-1", "uniprot_id": "CEA18_HUMAN", "id": "A8MTB9-1", "name": "Cell adhesion molecule CEACAM18", "aln": "---------------------------------MDLSRPRWSLWR----------RVFLMASLLACG--------------------------ICQASGQIFITQT--LGIKGYR----TVVALDKVPEDVQEYSWYWGANDSAGN----------MIISHKPPSAQQPGPMYTG-------------------------------------RERVNREGSLLIRPTALNDTGNYTVRVVAGNETQRATG---------------WLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNITWYVNDVP---------------TSSSDRMTISPDGKTLVILRVSRYDRTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRS--NPDDFNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS-------------------------DAKMNLSSLAWEQMG--RYRCTVE----NPVTQLIMYMDVRIQAPHEDLTCCPQRFLHLRIHGDVPHHAD--------SAG----WRLHLWSPDPCSDQPLLNQDKSGSM---------------------SVHPR-----------PEDKTRRASR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PQR1-1", "uniprot_id": "Q5PQR1_RAT", "id": "Q5PQR1-1", "name": "", "aln": "MAADVNFCQKSQRLGTEEQDGSCERLVSFEDVTVDFSQEEWQHLDSAQRCLYQEVMLEIYSHLLAVGYPRPEAILQMKNRKDTRLGQVDFLHQRCGQGQSEHDSPQQICVTTAFPRDASRVITRGGSYCSIMEEPWQGGDPKKTDQQNQIPPSSPGAFFSQKAVITDNCGGCEAAGGSIPLGPHLISTQKGSPRRCPCEKTLQPNLQTDSEHQSSATKQPNGVVDSCRLCTQGLSSAVCTTHSTGERACTGNQCANVLSPRSPLRQHGILSQDEPVEYTKDEKAFTAGSASCEQQTTNTLDLETHFICHICGKSFLQKSELSFHPGTSREETRYECPDCLKSLTTSPSSLQAHHEAHTKQKPYTCHDCGKSFSYASHLKVHLRIHTGERPYVCSDCGKAFSQKSVLTTHQRIHTGEKPYACSHCGKLFVYASDLRKHSRFHTGEKPYECRDCGKVFSNKSHLPVHRRIHTGEKPYKCRDCGKSFRRKSHLQVHGRTHTGEKPYACPDCGKAFSHSSVLSTHQRIHTGERPYVCSDCGKAMSSKAQLSEHQRVHTGEKPFVCVECGKAFGGRSSLQVHRRTHSGEKPFVCHKCGKGFLRKSQLSSHQQTHPGENP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:*: :. : : : **: * * . . . : : ::: .: * .* * ..: : ::* *. : : * :. :. ..: . :: : * :. : . :** ::. . : : .::. . * . .. : :: : ** .: .** . : * : :. :. * : . .:: :: : : .* . .* ..* : * * *.:: . . : *. : * *:* . ::* .: . . : : . * : : . . . * . : . ", "identical_positions": 35, "similar_positions": 115, "identity": "5.7%" }, { "cls_id": "homologset.agr.HGNC:31951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE93-1", "uniprot_id": "D3ZE93_RAT", "id": "D3ZE93-1", "name": "", "aln": "MEIQTWMPGCFSKGLLFSALFLALRLPQGSQAALHIQMIPEQPQKNQDLLLSLHGVPSTVQDFIWYLGEETSGGTRLFSYIPGLPRPQRDGNAMGQRDIVGFPNGSMLLRGAQPSDSGTYQVAATVNPAWTMKAKIDVQVADARK--VSSLLSANAGITTAIIVGSLAVGSLLLCGIAYLLVTRRHR---HR----KGQ------------------SPRNTATEKPEVNMSPESGDSNIYEVMPSPVFLVSPISDTEPGNPPVVSVSLPPPASQEPQPENQHY-QDLLNPDPAPYCQLVPTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z692-1", "uniprot_id": "CEA19_HUMAN", "id": "Q7Z692-1", "name": "Cell adhesion molecule CEACAM19", "aln": "MEIPMGTQGCFSKSLLLSASILVLWMLQGSQAALYIQKIPEQPQKNQDLLLSVQGVPDTFQDFNWYLGEETYGGTRLFTYIPGIQRPQRDGSAMGQRDIVGFPNGSMLLRRAQPTDSGTYQVAITINSEWTMKAKTEVQVAEKNKELPSTHLPTNAGILAATIIGSLAAGALLISCIAYLLVTRNWRGQSHRLPAPRGQGSLSILCSAVSPVPSVTPSTWMATTEKPELGPAHDAGDNNIYEVMPSPVLLVSPISDTRSINP---ARPLPTPPHLQAEPENHQYQQDLLNPDPAPYCQLVPTS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *****.**:** :*.* : *******:** **************::***.*.*** ******* ******:****: ******.****************** ***:******** *:*. ****** :****: .* *: *.:**** :* *:****.*:**:. ********. * ** :** *. ::*****:. : ::**.**********:********.. ** : .**.*. :.:***::* ******************", "identical_positions": 190, "similar_positions": 51, "identity": "62.71%" }, { "cls_id": "homologset.agr.HGNC:31952", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M601-1", "uniprot_id": "F1M601_RAT", "id": "F1M601-1", "name": "", "aln": "MTSLSSDLEHVSLPIQKDNLESPVPARRTSSRSPSSDEDPGLLSFSLAERNPPSPLVSGNLPFPASAPEKGKKQDDSEDSAEPEMLCSVEHPCQFFAEAQRLREQKLLLDEEVTVRGQVYGVHRVILAAISRLFRGRLLEGGGQQPGFSLDVTPRGWEAALTFAYEGVLGPAPQDEVLAAAKALGAPRVKIAAQLRPEGLGKAREDEKKLTQAEELRENLHSIERLYREGIGCDLELEAEGYRLQVHRVALACGSEFFGAMLLSGMRESQGTKVSLRTISSQDLRLLVSFAYTGVVRERWPGLLRAAQAALQYQSSSCLDLCQRALAQSLCPALCLALFPMIEAPGLEKVWKKAHHYLLTHLPAVASCPAFPSLPVTCLAELLDSDELHVQEEFEAFAAARCWLAANPETQESEAKALLRCVRFGRMSTRELRKVRAAGLPEPLQPDLLYQLMVEAEVPGQERWREPDQALVVIGGDGLRPDMDRRKPSCKVWWARAFHCGMGLVRTVEWCRLPNLPAPGRFRHGAASLTGGELYVCGGQDFYSPTNTLASTLRWSSSQEDWEEMAPLCQARSFFPLVVFDGQLYVLGGRDNGVALNSVETYNPELNVWRPAPALPAPCFAHAAAILEDRLYVSGGCSGTGQYLDSLIHYDPKLKKPGTLLSPMGVARASHVMAALGGKLYVAGGIGDTGDLLSFEAYEPKTDSWTHLASLPSPHVGAAGAVLQGELLVLGGYSHRTYAISHLVHAYCPGLDRWLCLGTLPRPRAEMPACVLTLSSVQHRALVPTQHQNKPAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UW92-1", "uniprot_id": "G3UW92_MOUSE", "id": "G3UW92-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLSGMRESQGTKVTLRTISSQDLRLLVSFAYTGVVRERWPGLLRAAQAALQYQSSSCLDLCQKALAQSLCPALCLALFPMIEAPGLEKVWGKAHDYLLSHLPAVASCPTFSSLPVTCLAELLDSDELHVQEEFEAFSAARCWLAANPETHESEAKALLRCVRFGRMSTRELRKVRAAGLPPSLPPDLLYQLMVEAEVPGQERWREPDQALVVIGGDGLRPDMDRRQPSCKVWWARAFHCGMGLVRTVEWCRLPNLPAPGRFRHGAASLTGSELYVCGGQDFYSHNSTLASTLRWSSSQEDWEEMAPLCQARSFFPLVVFDGQLYALGGRDNGVALNSVETYNPELNVWRPAPALPAPCFAHAAAILEDRLYVSGGCSGTGQYLDSLIHYDPKLKRPGTLLSPMGVARASHVMAALGGKLYVAGGVGDTGDLLSFEAYEPKSDSWTQLASLPSPHVGAAGAVLQGELLVLGGYSHRTYAISHLVHAYCPGLDRWLCLGTLPRPRAEMPACILTLPSVQHIALVPTQHQNKPAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NCF5-1", "uniprot_id": "KLH33_HUMAN", "id": "A6NCF5-1", "name": "Kelch-like protein 33", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLSGMRESQGTEVSLRTISTQDLRLLVSFAYSGVVRARWPGLLRAAQAALQYQSSSCLDLCQKGLARGLSPARCLALFPMAEAPGLERLWSKARHYLLTHLPAVALCPAFPSLPAACLAELLDSDELHVQEEFEAFVAARCWLAANPETQESEAKALLRCVRFGRMSTRELRRVRAAGLLPPLTPDLLHQLMVEADVPGQERRREPDRALVVIGGDGLRPDMALRQPSRAVWWARAFRCGVGLVRTVEWGQLPALPAPGRFRHGAASLAGSELYVCGGQDFYSHSNTLASTLRWEPSQEDWEEMAPLSQARSLFSLVALDGKLYALGGRHNDVALDSVETYNPELNVWRPAPALPAPCFAHAAAILEGQLYVSGGCGGTGQYLASLMHYDPKLEKPGTFLSPMGVPRAGHVMAALGGRLYVAGGLGETEDLLSFEAYELRTDSWTHLAPLPSPHVGAASAVLQGELLVLGGYSHRTYALSHLIHAYCPGLGRWLCLGTLPRPRAEMPACILTLPAVQHIALVPTPHQTKPAG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ************:*:*****:***********:**** *************************:.**:.*.** ******* ******::* **:.***:****** **:*.***.:******************** ************:**********************:****** .* ****:******:****** ****:************** *:** *******:**:******** :** **************:*.************ ..********..***********.****:*.**.:**:**.****.*.***:*******************************.:*******.****** **:******::***:******.**.********:******:*:* ********* ::****:**.*********.*******************:***:*******.******************:***.:*** ***** **.****", "identical_positions": 443, "similar_positions": 68, "identity": "55.86%" }, { "cls_id": "homologset.agr.HGNC:31955", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E8X2-1", "uniprot_id": "G5E8X2_MOUSE", "id": "G5E8X2-1", "name": "Polyadenylate-binding protein 5", "aln": "----------------------------MSLEAKYRAASLYVGDLHEDVTEDMLFRKFSTVGPVLSIRICRDLISQRSLGYAYVNFLQVNDAQKALVTMNFDVIKGKSIRLMWSQRDACLRRSGVGNVFIKNLDKSIDNKTLYEHFSPFGTIMSSKVMTDGEG-SKGYGFVHYQDRRAADRAIEEMNGKLLRESTLFVARFKSRKDREAELRDKPTEFTNVYIKNFGDDVDDEKLREVFSKYGQTLSVKVMKDATGKSKGFGFVSFDSHEAAKNAVEDMNGQDIN-GQTIFVGRAQKKVERQAELKEMFEQMKKERIRARQAAKLYIKNLDDTIDDETLRKEFSVFGSICRVKVMQ-EAGQSKGFGLICFFSPEAAAKAMAEMNGRILGSKPLNIALGQKH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L6B4-1", "uniprot_id": "A0ABK0L6B4_RAT", "id": "A0ABK0L6B4-1", "name": "Polyadenylate-binding protein 5", "aln": "----------------------------MSVETKYRAASLYVGDLHEDVTEDLLFRKFNTVGPVLSIRICRDLISHRSLGYGYVNFLQVGDAQKALETMNFDLIKGKSIRLMWSQRDACLRKSGIGNVFIKNLDKSIDNKTLYEHFSPFGKIMSSKVMTDEEG-SKGYGFVHYQDQRAADRAIEEMNGKLLRDSTLFVARFKSRKDREAELREKPAEFTNVYIKNFGDDMDDESLRSVFSKYGQTLSVKVMKDASGKSKRFGFVSFDSHKAAKNAVEDMNGRDIN-GQTIFVGRAQKKVERQAELKEMFEQMKKERIRARQAAKLYIKNLDDTIDDETLRKEFSVFGSICRVKVMQ-EAGQSKGFGLICFFSPEAAAKAMAEMNGRILGSKPLNIALGQKH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CB38-1", "uniprot_id": "PAB4L_HUMAN", "id": "P0CB38-1", "name": "Polyadenylate-binding protein 4-like", "aln": "----------------------------MNVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDIN-GQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQ-EEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQRH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21187-1", "uniprot_id": "PABP_DROME", "id": "P21187-1", "name": "Polyadenylate-binding protein", "aln": "------------------------------------MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFDLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKGYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDDEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQKKAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRSKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQIYQPNAASGFFVPTLPSNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGFQGTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITGQQTAAPNMQIPGAQIAGGAQQRTSNYKYTSNMRNPPVPQLHQTQPIPQQLQGKNSEKLIASLLANAKPQEQKQILGERLYPMIEHMHAN--LAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQVHRVTEPAN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04147-1", "uniprot_id": "PABP_YEAST", "id": "P04147-1", "name": "Polyadenylate-binding protein, cytoplasmic and nuclear", "aln": "MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELN-GEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARN--------------------------------------QMR-------------YQQATAAAAAAAAGMPG--QFMPPMFYGVMP--------PRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGPVYGVPPQGGFPRNANDNNQFYQ-------------------------------------QKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******** .*.* *: *.. *.* ***:*** ::: ****.**** : ..:*: :*: ::.: *:******. **:.* **:*****. ****::*: ** ** *:*.*: :* :* ***:.***:: . **. :*: :** **. ::*. . **:*: :* .. :**:*:**: : ** ::..* :* * .: .. ** * **** ::. : * **: :*. ::. *: ::*.***** ** **. :* : :: ..:*::*****::**: *. *: :*.* .*** * *:*****::** :.. *: *::* * :::..*** :*:.*:: ", "identical_positions": 145, "similar_positions": 120, "identity": "21.45%" }, { "cls_id": "homologset.agr.HGNC:31962", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ANF5-1", "uniprot_id": "A2ANF5_MOUSE", "id": "A2ANF5-1", "name": "", "aln": "MDPLQKWDPMSISVPSCIATVSSSQEASAAPQPSSSEKLSMGLSILSVSPSPRSSVPASLSEGLFQQQAREKKALWQQYWEKQGFPQRKKVFLRHSRRWHRDHMAPYLLERDLRGFPSGDKAQNQLR-----CQGHVQNIAGMSGQKNAAPNPPSWEMLVQGLNGLTLSLGANRPVPLPEEPWQQQEPEDMRQLERQQENLKMFQRMLK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDB6-1", "uniprot_id": "FA156_HUMAN", "id": "Q8NDB6-1", "name": "Protein FAM156A/FAM156B", "aln": "MDPLQKRNPASPSKSSPMTAAETSQEGPAPSQPSYSEQPMMGLSNLSPGPGPSQAVP--LPEGLLRQRYREEKTLEERRWERLEFLQRKKAFLRHVRRRHRDHMAPYAVGREARISPLGDRSQNRFRCECRYCQSHRPNLSGIPGESNRAPHPSSWETLVQGLSGLTLSLGTNQPGPLPEAALQPQETEEKRQRERQQESKIMFQRLLKQWLEEN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** :* * * .* :::..:***..*..*** **: **** ** .*.* .:** *.***::*: **:*:* :: **: * ****.**** ** ******** : *: * * **::**::* **.* *::*:.*:.* **:*.*** *****.*******:*:* **** . * **.*: ** *****. ****:** ", "identical_positions": 115, "similar_positions": 50, "identity": "53.49%" }, { "cls_id": "homologset.agr.HGNC:31963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BG41-1", "uniprot_id": "PSB11_MOUSE", "id": "Q8BG41-1", "name": "Proteasome subunit beta type-11", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MALQDVCKWQTPDTPRPSIHLPQAGGWAVPRGCDPQTFLQIHG-----P----RLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASRKVIPVHQRLLGTTSGTSADCATWYRVLRRELRLRELREGQLPSVAGTAKLLAAMMSCYRGLDLCVATALCGWDH-SGPALFYVYSDGTCLQGDIFSVGSGSPYAYGVLDRGYHYDMTIQEAYTLARCAVAHATHRDAYSGGSVDLFHVRESGWEYVSRSDACVLYRELQKARSLEQELEAKACGIYPEPATPQGARECKELFVEQEEVTPEDCAIIMKTETM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LAS0-1", "uniprot_id": "A0ABK0LAS0_RAT", "id": "A0ABK0LAS0-1", "name": "Proteasome subunit beta type-11", "aln": "MLVPLLSHDLEAFACLTSHTTKLRRTQLSPSACIQSSMGSCWSPASTHLWGKYRMTDRRLYWGLLQVSQQWKVRLTGGVLERWEALQACPVSPWQFSEVGGDPSPANSQACSETEKKRSISSHGSLAGSGYSPASPQRPSSSPAGPGLKCCPAPSNFHSASGMALQDVCKWQAPDTHGLSLRLPQAGGWAVPRGCDPQTFLQIYG-----P----RLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASRKVIPVHRHLLGTTSGTSADCATWYRVLRRELRLRELREGQLPSVAGTAKLLSAMMSRYRGLDLCVATALCGWDH-SGPALFYVYSDGTCLQGDVFSVGSGSPYAYGVLDRSYHYDMTVQEAYTLARCAVAHATHRDAYSGGSVDLFHVRESGWEYISRSDACVLYRELQEAQGFEQELEAKASEVLPEPATPQDARES-ELSVELEEVTPEDCKIIVKTETM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5LHX3-1", "uniprot_id": "PSB11_HUMAN", "id": "A5LHX3-1", "name": "Proteasome subunit beta type-11", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHG-----P----RLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDR-SGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKL--LEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30656-1", "uniprot_id": "PSB5_YEAST", "id": "P30656-1", "name": "Proteasome subunit beta type-5", "aln": "--------------------------------------------------------------------------------------------------------------------MQAIADSFSVPN-----------------------------RLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEE-------EGSFNNVIG-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8INY4-1", "uniprot_id": "Q8INY4_DROME", "id": "Q8INY4-1", "name": "Proteasome subunit beta", "aln": "------------------------------------------------------------------------------------------------------------------MALESICGMDKLP-------------------------------FMKSFGYR-TSKQTIEEIRVASSNMDNPLAIMAPPYENPRESVKKLN---ALSEVQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSP-EGPSLVYVDSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMTDIFSGGVVRLYHMDQGNWRNVANKDCQELHEQYSGVG----------NQQTP-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . . .* .*: :: . : *****:.* :: *:* ..*:*::.*. :.. : **: :: ::** :* :*** * * : **:*** : .* .::* :: : *:* .*.:. :.*: .** : ** *:* ::*.:*.**** . * *:** .*: *:: ::* *. :: *: * :*** * *:*: :..* .. * *. : . ", "identical_positions": 66, "similar_positions": 83, "identity": "13.92%" }, { "cls_id": "homologset.agr.HGNC:31966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q149M0-1", "uniprot_id": "CL12B_MOUSE", "id": "Q149M0-1", "name": "C-type lectin domain family 12 member B", "aln": "MSDEVTYATLMLQDSARVRGNQDGNNLRKEGHPAQSSLWRGAALSLMTLCLVLVTGLVTLATMFLQVSNDINSDSEKLSQLQKSIHPQQDNLSESLNSSR-KSLTEESLQSQISALLERQEQMATKLCKEFLIHASDHKCNPCPKTWQWYGNSCYYFSINEEKSWSDSRKDCIDKNATLVKIDSTEERDLLQSQLSLTFSFFWLGLSWNSSGRNWLWEDGSFPPPTLFSDKELASFNGSRDCAYFERGNIYASRCSAEIPWICEKTASLVKTEDLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABQ8-1", "uniprot_id": "D4ABQ8_RAT", "id": "D4ABQ8-1", "name": "", "aln": "MSDEATYTTLMLQDSAGVRGNQDANNLRKEECPAQSPLWRGAALSLMTLCLMLVTGLVTLATMFLQVSNDINSDSEKLSELQKIIHPQQDNLSESLNNSR-KGLTEESLQSQISALLERQGQMATKLCKEFLIHASDHKCNPCPKTWQWHGNSCYYFSANEEKSWRDSRKDCTDKNATLVKIDSIEERDLLQSQLSLTFSFFWLGLSWDSSSRNWLWEDGSLPPPTLFNEKELASFNGSRECAYFERGNIYVSRCSAEISWICEKTASLVKIEDLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2HXU8-1", "uniprot_id": "CL12B_HUMAN", "id": "Q2HXU8-1", "name": "C-type lectin domain family 12 member B", "aln": "MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTLGMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQMAIKLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLVKIDSLEEKDFLMSQPLLMFSFFWLGLSWDSSGRSWFWEDGSVPSPSLFSTKELDQINGSKGCAYFQKGNIYISRCSAEIFWICEKTAAPVKTEDLD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.**:** :**** .*.*:*.*****. ** *.:** ***.*:****:*: *****. ****:************:*** *: ******:.*..*. .: ** *:****::*:** *** ***:*::**:***:****** ***: ******: ****:* :***** ***:******* **:*:* ** * **********:**.*.*:*****.*.*:**. *** .:***: ****::**** ******* *******: ** ***:", "identical_positions": 186, "similar_positions": 57, "identity": "67.39%" }, { "cls_id": "homologset.agr.HGNC:31969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LX24-1", "uniprot_id": "A0ABK0LX24_RAT", "id": "A0ABK0LX24-1", "name": "", "aln": "MASRVNTTFTLIPSSKCRRLNHQSSDFCNTLDSDPQLLSTLGNFKVLPLEILHIILRYLSVKDIGMLSMVSKTVSQHIINYISTSSGSRRLLLQNFHDLDLPGTKEETALLEHYRALGLLFKRCTLLLPTKERLKYIQKILSEVPCFKFSGCSAPLQCLGLSCYGMFLQTLTAGWDELECHRVYNFLCEQTNLSRKMQTVVCNKPGSARKLELRVRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPTSPHDGQVIWQEMIEGPTDESSLKGLANAIKLLYDTGAKGWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAIELARLIVFLALVCEKELYCMDWTVRMMQKVCKVFNTATERKSFLQSVANAFACVTMEMLQPVMSGERDDDDRGFLNLFHLLHAQANFHKEVLYLTMNAVSS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A6H3-1", "uniprot_id": "FBX47_MOUSE", "id": "A2A6H3-1", "name": "F-box only protein 47", "aln": "MASRVNTSFTLIPKQKCRRSNHHSSYFCNTLDSDPQLLSTLGNFKVLPLEILHIILRYLSVKDIGMLSMVSKTVSQHIINYISTSSGSRRLLLQNFHDLDLPGTKEETALLEHYRALGLLFKRCTLLLPTKERLKYIHKILSEVSCFKFSGCSVPLQCLGLSCYGMFLQTLTAGWDELECHRVYNFLCELTNLSRKMQTVVCNKPGSARKLELRVRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPTSPHDGQVIWQEMIEGPTDESSLKGLANAIKLLYDTGAKGWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAVELARLVVFLALVCEKELYCMDWTVRMMQKVCKVFSTAAERKSFLQSIANAFACVTMEMLQPVMSGDRDDDDRGFLNLFHLLHAQANFHKEVLYLTMNAISS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5MNV8-1", "uniprot_id": "FBX47_HUMAN", "id": "Q5MNV8-1", "name": "F-box only protein 47", "aln": "MASRINTNFTLIPNQKLRRSNRQTSCYSKTLGSGFQPISTFGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHNLELPDRRQDSAILEHYRSLGLLFKRCTLLLPTKERLKYIHKILTEVSCFKFNGCAAPMQCLGLTCYGMFLQTLTAGWDELECHRVYNFLCELTNLCRKIQMAVCSKPGSAQKLELRIRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPISPQDGQVVWQEMIEEPTDEFSLKGLADAIKLLYDASTKEWTADDVISLVDELSVVPREWLLENNARLLMLSGNNICFSFMASKAVNGRTIELARLVVFLALVCEKELYCMDWTVKMMQKVCKVFSTPVERKNFLQNVANAFACVIMEMLQSIMSGDRDEDDRSFLNLFHLVHAQANFHKEVLYLTMNTPLST", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**.*****..* ** *:::* :.:**.*. * :**:****.*****::***:*******.***********************:*****:**:*:**. ::::*:*****:*********************:***:**.****.**:.*:*****:*************************** ***.**:* .**.*****:*****:******************************************** **:****:****** **** ******:*******:.:* *****************************:********:**********::*****:******************:*********.*..***.***.:******* *****.:***:**:***.*******:****************: * ", "identical_positions": 367, "similar_positions": 69, "identity": "81.19%" }, { "cls_id": "homologset.agr.HGNC:31971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3YUK0-1", "uniprot_id": "D3YUK0_MOUSE", "id": "D3YUK0-1", "name": "", "aln": "-----------------MSGQTPPT------HTLLTHEALIMSSLEELPTVVFPALFKEAFAGRQTNLLKAMVAAWPFPCLHVGSLMK--KP-NLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDYKSKTLDEKQ-LVKVLPRYARR-QRLKVIVNLSISSHFNK--SKAYFLNWAKQRIGSLYFCCIKMKIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFAPYFGHMKNLQKVFLAPLHKNTSPIINITSATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRGLLQKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYNELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPIFCSCFQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E0CZF1-1", "uniprot_id": "E0CZF1_MOUSE", "id": "E0CZF1-1", "name": "", "aln": "-----------------MSGQTPPT------HTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMK--KP-NLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQ-LVKVLPRYARR-QRLKVIVNLSISSHFNK--SKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QPH3-1", "uniprot_id": "J3QPH3_MOUSE", "id": "J3QPH3-1", "name": "", "aln": "-----------------MSGQTPPTLQKRARQTQLRDEALAISPLENVPAVYVPWLFQEAFAGRYNSLIKTMVAAWPFQYLPVGSLIN--MH-NLETLQALLDGVDRRLTRKFPPGRPKLQVLDMRNVHHVFWNIGSDANDSDSDAETLDEKQ-VVKALPRYALR-QRLKIIVDLSISSQLNE--EKAYFLNWAKQRKGSINFCCTKMKIWDAPDKVIREIMNVFHPEHITELELYTDWTLLRLAHFAPYFGQMKNLEKVFLAPLHKNTSPIMNITGASKVKCIKKIISQFSKFNCLQHVFMKRVHFLRDHLHQILGCLRTPLQTLSITHCLISQTDLDSFSCCHNLFKLKNLEIRGVTLFALDLMPLRGLLGKLAGTLKSLDFQWCSMKDSQLIVLLPALSQCSQLNQINFYSNDFSMAILKDLLQHTATWSKMNVEQYPVPLECYDALGHVSRERFVELCQELMDTLRAKREPKSISFATNVCQNCGKTCVYGQGARLCSCLQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QK78-1", "uniprot_id": "J3QK78_MOUSE", "id": "J3QK78-1", "name": "", "aln": "-----------------MSGQTPPTLQKRARQTQLRDEALAISPLENVPAVYVPWLFQEAFAGRHNSLIKTMVAAWPFQYLPVGSLIN--MH-NLETLQALLDGVDRRLTRKFPPGRPKLQVLDMRNVHHVFWNIGSDANDSDSDAETLDEKQ-VVKALPRYALR-QRLKIIVDLSISSQLNE--EKAYFLNWAKQRKGSINFCCTKMKIWDAPDKVIREIMNVFHPEHITELELYTDWTLLRLAHFAPYFGQMKNLEKVFLAPLHKNTSPIMNITGASKVKCIKKIISQFSKFNCLQHVFMKRVHFLRDHLHQILGCLRTPLQTLSITHCLISQTDLDSFSCCHNLFKLKNLEIRGVTLFALDLMPLRGLLGKLAGTLKSLDFQWCSMKDSQLIVLLPALSQCSQLNQINFYSNDFSMAILKDLLQHTATWSKMNVEQYPVPLECYDALGNVSRERFVELCQELMDTLRAKREPKSISFATNVCQNCGKTCVYGQGARLCSCLQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3YUJ6-1", "uniprot_id": "D3YUJ6_MOUSE", "id": "D3YUJ6-1", "name": "", "aln": "-----------------MSGQTPPTLQKRARQTQLRDEALAISPLENVPAVYIPWLFQEAFAGRHNSLIKTMVAAWPFQYLPVGSLIN--MH-NLETLQALLDGVDRRLTRKFPPGRPKLQVLDMRNVHHVFWNIGSDANDSDSDAETLDEKQ-VVKALPRYALR-QRLKIIVDLSISSQLNE--EKAYFLNWAKQRKGSINFCCTKMKIWDAPDKVIREIMNVFHPEHITELELYTDWTLLRLAHFAPYFGQMKNLEKVFLAPLHKNTSPIMNITGASKVKCIKKIISQFSKFNCLQHVFMKRVHFLRDHLHQILGCLRTPLQTLSITHCLISQTDLDSFSCCHNLFKLKNLEIRGVTLFALDLMPLRGLLGKLAGTLKSLDFQWCSMKDSQLIVLLPALSQCSQLNQINFYSNDFSMAILKDLLQHTATWSKMNVEQYPVPLECYDALGHVSRERFVELCQELMDTLRAKREPKSISFATNVCQNCGKTCVYGQGARLCSCLQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0J9YU01-1", "uniprot_id": "A0A0J9YU01_MOUSE", "id": "A0A0J9YU01-1", "name": "", "aln": "-----------------MSGQTPPTLQKRARQTQLRDEALAISPLGNVPAVYVPWLFQEAFAGRHNSLIKTMVAAWPFQYLPVGPLIN--MH-NLETLQALLDGVDRRLTRKFPPGRPKLQVLDMRNVHHGFWNIGSDANDSDSDAETLDEKQ-VVKALPRYALR-QRLKIIVDLSISSQLNE--EKAYFLNWAKQRKGSINFCCTKMKIWDAPDKVIREIMNVFHPEHITELELYTDWTLLRLAHFAPYFGQMKNLEKVFLAPLHKNTSPIMNITGASKVKCIKKIISQFSKFNCLQHVFMKRVHFLRDHLHQILGCLRTPLQTLSITHCLISQTDLDSFSCCHNLFKLKNLEIRGVTLFALDLMPLRGLLGKLAGTLKSLDFQWCSMKDSQLIVLLPALSQCSQLNQINFYSNDFSMAILKDLLQHTATWSKMNVEQYPVPLECYDALGHVSRERFVELCQELMDTLRAKREPKSISFATNVCQNCGKTCVYGQGARLCSCLQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A5E7-1", "uniprot_id": "A0A8I6A5E7_RAT", "id": "A0A8I6A5E7-1", "name": "", "aln": "-----------------MSGHIPPTLQKLARQTLLRNEAMAIACLGELPTMLFPALFKEAFEGRHINLIKEMVAAWPFPCLPVGALMK--TP-NGETMKALLDGVDMRLTRKFHPRRTKLQVLDLRNVHHNFWNIWTGVEDSSHSAENLEEKQ-VAKFFPRYALRRQRVKVIVELSIFSCLEE--ERACFLTWAQERKGFLHFCCTKMTIWDLPVHVIREILNVFDPQHITEFELHTEWTLLELAHFSPYFGQMRNLRKVFLEPLKGMISSNHNETGDREAKCIKKFISQFSKFNCLQHLSMFCPHFLRDHMNQVLGCLMTPLETLSVTCYIISQNELNSFSCCKSLFQLKHLELRGVILHDVDIMSLRGFLEKVADTLETLDLQCCRMKDSQLYALLPALRHFSQLTTVKFYSNKFSMPILKDLLQHTANWSKVNVEQYPAPLECYDDSAQVSVERFAQLCSELMDTLRAIRQPKNISFATEICYTCGERCVYHNGPRLCCCWQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZKI3-1", "uniprot_id": "A0A8I5ZKI3_RAT", "id": "A0A8I5ZKI3-1", "name": "", "aln": "-----------------MSGHTPPTLEKLARQTLLRNEAMAISCLGELPTILFPALFKEAFEGRHINLIKEMVAAWPFPCLPVGALMK--TP-NGETMKALLDGVDMRLTRTFHPKRTKLQVLDLRNEHHNFWNIWTGAEDSSHSAENLEEKQ-VAKVFPRYALRRQRVKVIVELSIFSCLEE--QQACFLKWAQERKGSLHFCCTKMTIWDLPVHVIREILKVFDPQHITEFELHNEWTLLELAHFAPYFGQMRHLRKVSLAPLK-IISSNRNETGDREATCIKKFISQFSKFNCLQHLSMFYCHFLRDHMNQVLRYLMTPLETLSVTCYIISQNDLDSFSCSQSLFHLKHLELIGVLLYGLDVMPLRGLLEKVADTLETLNLQWCGMKDPQLYALLPALRNCSQLTTVKFYSNKFSMPILKDLLQHTANWSQVNVEQYPAPLECYDDSSQVSVARFSQLCRELTDTHRAIRQPKNISFATEICYTCGKRCVYHNGPRLCCCWQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LJH5-1", "uniprot_id": "A0ABK0LJH5_RAT", "id": "A0ABK0LJH5-1", "name": "", "aln": "-----------------MSFQTPPTLQKLARQTLLRNEAVAMSCVGELPIVLFPALFKEAFEGRHINLVKEMVAAWPFPCLPVGALMK--TP-NAETLQAVLDGVDMRLTRKFHPRRIKLQVLDLRNVKHAFWNTWTGAEDCSCSAENLEEKQ-VVKVFPRYALRRQRVKVITELSIFSCLEE--QQACFLKWAQERMGSLYFCCTKMKIWDLPVCVIREILNVFDPQHITELELHTEWTLLELEHFAPYFGQMRNLRKVFLEPFHKVTLSNRNETRDREAKCIKKFISQFSKFNCLQHLCMFCTHFLRDHMNQVLGCLMTPLETLSVTCCVISQNDLDSFSCCLSLFHLKHLDLRGVVLHDLDVMPLRVLLEKVADTLETLDLQWCRMKNSQLYALLPALRHCSQLTTVKFYSNKFSMPILKDLLQHTANWSKVNVEQYPAPQECYDDSSQVSVERFSQLCHELMDTHRAIRQPKNISFATEICYTCGERCVYHNGPRLCCCLQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZL15-1", "uniprot_id": "A0A8I5ZL15_RAT", "id": "A0A8I5ZL15-1", "name": "", "aln": "LCYSSSPRNGHVALDLKMSVQSPPTLEKLAIQSLLRNEDVAMSSLGELPAVLFPALFKEAFTGKHINFVKEMVASWPFPCLPVGALMK--TP-NLEMLQAVLDGVDMRLTRKFHPRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENLKEKK-VMKVFHRYALR-KRVKVIVDLYICSCLKE--EQTCLLKWAQQRKGSLHFCCTKMKVWNLPVCVIREILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGIGDREAKCIKKFISQFSKFNCLQHLCMFCVHFLGDHMNQVLGCLMTPLETLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCRMTDSQLYALLPALRHCCHLTTVNFYSNNFSVPILKDLMQHTANWSRIRVEQYPAPLECYDDLAQVSVERFAEFSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGCRLCCCWH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A1M8-1", "uniprot_id": "A0A8I6A1M8_RAT", "id": "A0A8I6A1M8-1", "name": "", "aln": "--FTRCFLTG----DLKMSVQSPPTLEKLAIQSLLRNEDVAMSSLGELPAVLFPALFKEAFTGKHINFVKEMVAAWPFPCLPVGALMK--TP-NLEMLQAVLDGVDIQLTRKFHPRRTKLQVLDLRNMHHYFWNIQGGEEDSSCSAENLKEKK-VMKVFHRYALR-KRVKVIVDMYICSCLKE--EQTCLLKWAQQRKGSLHFCCTKMKVWNLPVCVIREILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGIGDREAKCIKKFISQFSKFNCLQHLCMFCVHFLGDHMNQVLGCLMTPLETLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCHLTTVNFYSNNFSVSILKDLMQHTANWSRIRVEQYPAPLECYDDLAQVSVERFAELSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6B4R9-1", "uniprot_id": "A0A8I6B4R9_RAT", "id": "A0A8I6B4R9-1", "name": "", "aln": "-----------------MSVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALF-EAFTGKHINLVKEMVSAWPFPCLPVGALMK--TP-NLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKK-VVKVFHRYALR-KRVKVIVELYIHSCLKE--EQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLETLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAELSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M1V6-1", "uniprot_id": "A0ABK0M1V6_RAT", "id": "A0ABK0M1V6-1", "name": "", "aln": "-----------------MSIPTPLTLQMLARQSLLRNEDVAISSLEEMPNVLFPALFKEAFEGRQTKLVKETVATWPLPCLPVGALMN--TQ-SLETFQAVLDGVDMRLTRKFHPR-TKLQVLDLRNAHHAFWNIWAGAEESSCSAENWEEKQ-VVKVLPRYALRRQRVKVIVELCIWSCLDE--TQAYFLKWAQQRKGSLHFCCTQMTIWELPLRVLKEILNVFNPQHITELELNTEWNLSDLAHFAAYFGKMINLQKVFLAPLHKMTLSNSTETRDRETKCIKKFISQFSKFNCLQHLCMFCVHFLRDHMNQVLGCLMTPLETLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCRMTDSQLYALLPALRHCCQLTMVNFYSNNFSMHILKDLLQHTINWSRINVEQYPAPLECYDDSAQVSVERFALLCPELMDTLRAIRQPKSISFATDTCQRCGECCVYHNGSRLCCCWQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LXK5-1", "uniprot_id": "A0ABK0LXK5_RAT", "id": "A0ABK0LXK5-1", "name": "", "aln": "-----------------MSIPTPLTLQMLARQSLLRNEDVAIFSLEEMPNVLFPALFKEAFEGRQTKLVKEMVATWPLPCLPVGALMK--TP-SLETFQAVLDGVDMRLTRKFHPR-TKLQVLDLRNAHQSFWNIWAGAEESSCSAENWEEKQ-VVKVLPRYALRRQRVKVIVELCIWSCLDE--TQAYFLKWAQQRKGSLHFCCTQMTIWELPLIVLKEILNVFNPQHITELELNTEWNLSDLAHFAPYFGKMINLQKVFLAPLHKMTLSNSTETRDRETKCIKKFISQFSKFNCLQHLCMFCVHFLRDHMNQVLGSLMTPLETLSITYYLISQKDLDSLSRRQSLFQLKHLDLSGVVLCDLDIMPLRGLLEKVADTLETLDLKWCRMNDSQLYALLPALRHCCQLTMVNFYSNNFSMHILKDLLQHTINWSRINVELYPAPLECYDDLAQVSVERFALLCPEIVDTLRAIRQPKSISFATDTCQRCGEHYVYHNGSRLCCCWQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "K9J7D1-1", "uniprot_id": "K9J7D1_MOUSE", "id": "K9J7D1-1", "name": "", "aln": "-----------------MNVHTPPTLQKLAIQTLVREEALGMSDLEEMAHGLFPALFKEAIDGRYIKLIKALVIAWPFHCLPVGALMR--TT-DLETLQAVLDGVDIRRTIGFHPRRKKLQYLDLRNVHHSFWNIWTDSEDSDYSAEILDEKK-ALQVRPRYALR-QRLKVTVDLCIRSCLDE--AQTWFLKWAQERKGSLYFCCTKMKIWTLPVKALRHIFHIFDPEHIMELELNTEWTLLELTHFAPYFGQMRNLCKVFLAPLHKIDFHLPNRTRVTEVKCINKFASQFSKFNCLQHLFMFCVHFLRSQMNQVLGCLMTPLKTFSITYSLISQRDLDSFACCQSLFQLKHLELRGVVLLDLDLMPLRGLLMKVAGTLETLDLQGCRMKDSQLSVLLPAFKQCSQISNINFYNNEFSMPFLKDLLQHTANWSKMNVEQYPAPLECYDEFAQVSVERFVRLCQDLMDTLRAIRQPKNTSFATDICHTCGERWVFDQVANLCRCWQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0J9YUM1-1", "uniprot_id": "A0A0J9YUM1_MOUSE", "id": "A0A0J9YUM1-1", "name": "", "aln": "-----------------MNVHTPPTLQKLAIQTLVREEALGMSDLEEMAHGLFPAHFKEAIDGRYIKLIKALVIAWPFHCLPVGALMR--TT-DLETLQAVLDGVDIRRTIGFHPRRKKLQYLDLRNVHHSFWNIWTDSEDSDYSAEILDEKK-ALQVRPRYALR-QRLKVTVDLCIRSCLDE--AQTWFLKWAQERKGSLYFCCTKMKIWTLPVKALRHIFHIFDPEHIMELELNTEWTLLELTHFAPYFGQMRNLCKVFLAPLHKIDFHLPNRTRVTEVKCINKFVSQFSKFNCLQHLFMFCVHFLRSQMNQVLGCLMTPLKTFSITYSLISQRDLDSFACCQSLFQLKHLELRGVVLLDLDLMPLRGLLMKVAGTLETLDLQGCRMKDSQLSVLLPAFKQCSQISNINFYNNEFSMPFLKDLLQHTANWSKMNVEQYPAPLECYDEFAQVSVERFVRLCQDLMDTLRAIRQPKNTSFATDICHTCGERWVFDQVANLCRCWQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N456-1", "uniprot_id": "L7N456_MOUSE", "id": "L7N456-1", "name": "", "aln": "-----------------MNVHTPPTLQKLAIQTLVREEALGMSDLEEMAHGLFPALFKEAIDGRHIKLIKALVIAWPFHCLPVGALMR--TT-DVETLQAVLDGVDIRRTIGFHPRRKKLQFLDLRNVHHSFWNIWTDSEDSDYSAEILDEKK-ALQVRPRYALR-QRLKVTVDLCIRSCLDE--AQIWFLKWAQERKGSLYFCCTKMKIWTLPVKALRHIFHVFDPEHIMELELNTEWTLLELTRFAPYFGQMRNLRKVFLAPLHKIDFHLPNRTRVTEVKCINKFASQFSKFNCLQHLFMFCVHFLRSQMNQVLGCLMTPLKTLSITYSLVSQRDLDSFACCQSLFQLKHLELRGVVLLDLDLMPLRGLLMKVAGILETLDLQGCRMKDSQLSVLLPAFKQCSQISNINFYNNEFSMPFLKDLLQHTANWSKMNVEQYPAPLECYDEFAQVSVERFAQVCQDLMDTLRAIRQPKNSSFATDICHTCGERWVFDQVANLCHCWQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0J9YUV1-1", "uniprot_id": "A0A0J9YUV1_MOUSE", "id": "A0A0J9YUV1-1", "name": "", "aln": "-----------------MNVHTPPILQKLAIQTLVREQALGMSDLEEMAHGLFPALFKEAIDGRYIKLIKALVIAWPFHCLPVGALMR--TT-DLETLQAVLDGVDIRRTIGFHPRRKKLQFLDLRNVHHSFWNIWTDSEDSDYSAEILDEKK-ALQVRPRYALR-QRLKVTVDLCIRSCLDE--AQTWFLKWAQERKGSLYFCCTKMKIWTLPVKALRHIFHVFDPEHIMELELNTEWTLLELTRFAPYFGQMRNLHKVFLAPLHKIDFHLPNRTRVTEVKCINKFASQFSKFNCLQHLFMFCVHFLRSQMNQVLGCLMTPLKTLSITYSLVSQRDLDSFACCQSLFQLKHLELRGVVLLDLDLMPLRGLLMKVAGILETLDLQGCRMKDSQLSVLLPAFKQCSQISNINFYNNEFSMPFPKDLLQHTANWSKMNVEQYPAPLECYDEFAQVSVERFAQVCQDLMDTLRAIRQPKNSSFATDICHTCGERWVFDQVANLCHCWQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0J9YVD0-1", "uniprot_id": "A0A0J9YVD0_MOUSE", "id": "A0A0J9YVD0-1", "name": "", "aln": "-----------------MTVQTPSTLQNLALQALLRDEALALSCLEEVPFLLFPALFKEAFAGRLKKLMKAIVAAWTFPCLPVGALMK--SP-NLETLQAVLDGIDMQLTRESHP-RGKLQVLDLRNVHHAFWDIWAGAEDGSCSSESLNEKPTVVKVLRRYAQR-KQLKVVADLCLRPRRDE--TQAYFLKWAQQRKDSLHLCCINMKIWAMPVDFVLEILNVFHPEHIEEFELNTEWNVFNLARFAPCLGQMRNLRKLLLAPLYKNVFKIANRTGDREDKCVKEFVSIFSKFNCLQHLSMQGVHFLTDHMSQVFRCLMTPLESLSITHYQISQSDLDSFSCCQSLFQLKHLEMKGMVLQVLDVMPLRGLLEKVAKTLETLNLQGCKLKDSQLNALLPSFIRCSQLTKINLYNNDFSMPILKDLLQQTANWNKMNVEQYPAPLECYNELGHVSVERFAQLCQELMDTLRAIRQPKSLSFATRICHKCGEPCVYGQGGRLCFCWR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0J9YU88-1", "uniprot_id": "A0A0J9YU88_MOUSE", "id": "A0A0J9YU88-1", "name": "", "aln": "-----------------MTVQTPSTLQNLALQALLRDEALALFCLEEVPFLLFPALFKEAFAGRLKKLMKAIVAAWTFPCLPVGALMK--SP-NLETLQAVLDGIDMQLTRESHP-RGKLQVLDLRNVHHAFWDIWAGAEDGSCSSESLNEKPTVVKVLRRYARR-KQLKVVADLCLRPRRDE--TQAYFLKWAQQRKDSLHLCCINMKIWAMPVDFVLEILNVFHPEHIEEFELNTEWNVFNLARFAPCLGQMRNLRKLLLAPLYKNVFKIANRTGDREDKCVKDFVSIFSKFNCLQHLSMQGVHFLTDHMSQVFRCLMTPLESLSITHYQISQSDLDSFSCCQSLFQLKHLEMKGMVLQILDVMPLRGLLEKVAKTLETLNLQGCKLKDSQLNALLPSFIRCSQLTKINLYNNDFSMPILKDLLQQTANWNKMNVEQYPAPLECYNELGHVSVERFAQLCQELMDTLRAIRQPKSLSFATRICHKCGEPCVYGQGGRLCFCWR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QMM8-1", "uniprot_id": "J3QMM8_MOUSE", "id": "J3QMM8-1", "name": "", "aln": "-----------------MSVQTPSTLQNLTLKALLRDEALALSCLEEVPFLLFPALFKEAFAGRLKKLMKAIVAAWTFPCLPVGALMK--SP-NLETLQAVLDGIDMQLTRKSHP-RGKLQVLDLRNVHHAFWDIWAGAEDGSCSSESLNEKPTVVKVLRRYARR-KQLKVVADLCLRPRRDE--AQAYFLKWAQQRKDSLHLCCINMKIWAMPVDFVLEILNVFHPEHIEEFELNTEWNVFNLARFAPCLGQMRNLRKLLLAPLYKNVFKIANRTGDREDKCVKEFVSIFSKFNCLQHLSMQGVHFLTDHMSQVFRCLMTPLESLSITHYQISQSDLDSFSCCQSLFQLKHLEMKGMVLQVLDVMPLRGLLEKVAKTLETLNLQGCKLKDSQLNALLPSFIRCSQLTKINLYNNDFSMPILKDLLQQTANWNKMNVEQYPAPLECYNELGHVSVERFAQLCQELMDTLRAIRQPKSLSFATRICHKCGEPCVYGQGGRLCFCWR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6V4-1", "uniprot_id": "D4A6V4_RAT", "id": "D4A6V4-1", "name": "", "aln": "-----------------MSVQSPPTFQKLARQTLLRNEAVIISFLEELPTVLFPALFKEAFEGRHSKLMKEQVTTWPFPCLPVGALMK--TP-NLETLHAVLEGVDMLLTRDIHHSKRKFQFLALRNVHHMFWHIWADEEDGSCSSESLDENP-VVKVLPRYALR-HKLKVVTELCFRPRLDE--AQACFLKWAQQRNGFLYFCCMKLKIWAMPMDFIREILNVFHPEHIE-LELNTEWNVFQLAQFASFFGQMRNLRKLLLAPLYKNVFKIANRTGEREDKCVKGFISMFSKFNCLQHLSLCGVHFLRDHMNQVFRSLMTPLVKLSIKHYRISQKDLDSFSCCQSLFHLKHLEMSGVTLSSLDIMPLRSLVEKVADKIQTLDLQGCRMKDYQLNALLPALTQCCQVAKINFYNNDFSMHILKDFLKHTATWSKINVEQYPAPLECYDELAHVCRERFAQLCLELIDTLGTIRQLKIISFATNMCHKCGMQCVYG--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "L7MTS5-1", "uniprot_id": "L7MTS5_MOUSE", "id": "L7MTS5-1", "name": "", "aln": "-----------------MSTYNPPTLLQLALDEVVKKDSIDFSDLEDLPITLFPPLFIKAFNSRHTEIVKKMVATWPFPCLPVGALLK--TA-GVEMLQAVLDGIDILLTQNVSLR-RKLQVVDMRDVHQDFWDVWTGKNDGVHSADEGIKEP-ISKHVPKYALR-RLLKVVTDLSLFFYLNT--HQRCFLQWAQQRNEYVRLCCLKMKILAFPVENIKWILNIFHPNYIEELEIYTNQVLPFLSCFAPCFGQMRNLLRFHVCQIYLMSGSGVYRFAEVK-RGAAKFLSQFSKLKCLQHLSMNGDYFSRYHMKHLFRCLKSPLESLSMNRCQLSKSDFKHMSDCQRLYQLKHLQFHGVEFPKSGFKSLQILLKNVSETLQTLKFEHCKMNDSQLKVLLPALSQCSQLTMVNFCDNDFSNLVLKDLLKCMANLSKLCVEQYPAPLECYDHRRNVVVEEFVQLCSDLMDILIAKRQPKTIIFATDTCSHCLRRCIYGRKTSLCLCWQQREV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ASI9-1", "uniprot_id": "A2ASI9_MOUSE", "id": "A2ASI9-1", "name": "", "aln": "-----------------MSFQDPPTLLSLAVQSLVKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGSWPLLCLPVGALMN--VP-DMSILQAVLDGVDMQLTGNFHPRKRKLQVLDLRNVHHHFWDVSAGPEDGDGSAETVCQKQ-KATRPHRYALR-RRLKVVTDLCLQFDLEE--HQTYFLQWAQERRCSLNLCCVKMQIRELPIHTVRKILQIFQPYCIEELELNTGWTLSTLACFTPCLGQMKNLRKLHLTLVHEKLFTFLRTSTDIQEKSVTKFISQFSKLNSLQHLNLTGLYFLTGHINELLGCLKTPLEFLSIALCKYSQSDMESFAQCQSLHHLKHLHLAGIILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVSAFIPALNKCSQLIEVNFCDNDISTSVLMNLLHHTANLSQLIMELYPAPLECYETGFVLRAERFVQLSSELMNILCTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1ARV5-1", "uniprot_id": "B1ARV5_MOUSE", "id": "B1ARV5-1", "name": "", "aln": "-----------------MSFQAPPTLLSLAVQSLAKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGAWPLPCLPVGALMN--IP-DMTVLQAVLDGVDMQLTGNFHPSKRKLQVLDLRNVHHHFWDVSAGPEDEDSSAETVCQKQ-KATHPHRYALR-RRLKVVTDLHLQFDLEE--HQTYFLQWAQERRASLNLCCVKLQIRGLAMHTVRKILQIFQPYCIEELELNTGWTLSTLACFAPCLGQMKNLRKLHLTLVHEKLFTFLHTSTDIQEKSVTKFISQFSKLNSLQHLALAGLYFLTGHMNELLGCLKTPLEFLSMALCKYSQSDMESFAQCQSLHHLKHLHLAGIILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVIAFIPALNKCSQLIEVNFCDNDISTSVLMNLLHHTANLSQLIMELYPAPLECYETGFVLRAERFVQLSSELMNILRTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ASJ0-1", "uniprot_id": "A2ASJ0_MOUSE", "id": "A2ASJ0-1", "name": "", "aln": "-----------------MNFQAPPTLLSLAVQSLAKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGAWPLPCLPVGALMN--IP-DMTVLQAVLDGVDKQMTGNFSPRNQKLQVLDLRNVHHHFWDVSAGPEDGDGSAETVCQKQ-KATRPHRYALR-RRLKVVTDLPLQFDLEE--NQTYFLQWAQERRGFLHLCCMKMQIRGLTIHTVRKILQIFQPYCIEELELNTGWTLSTLACFTPCLGQMKNLCKLHLTLVHEKLFTFLRTSTDIQEKSVIKVISQFPKLNSLQHLDLTGLYFLTGHMNELLGCLKTPLEFLSIALCKYSQSDMESFAQCQSLHHLKHLHLAGIILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVSAFIPALNKCSQLISVNFCDNDISISVLTNLLHHTANLSQLIMELFPAPLECYETGFVLRAERFVQLSSELMNTLCTVRQPHSICFASQLCLICSQHCTYGLETRLCHCCQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7MU96-1", "uniprot_id": "L7MU96_MOUSE", "id": "L7MU96-1", "name": "", "aln": "-----------------MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLID--KP-NLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETIPEKQ-EVEG---HSRR-QRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALEVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGR-----HTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRCLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTRCIYGNQTTFCECLE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AGW5-1", "uniprot_id": "A2AGW5_MOUSE", "id": "A2AGW5-1", "name": "", "aln": "-----------------MSFKDPPTLQQLARRSLLKDEALTISALPNLPVQLFPPLFKDAFTSRHPNILRQMVAAWPFPTLPVGALMK--IP-HLETLKAVLDGLDLLMSQKDRPSRWNLQVLDLRDAHQDFWDGWAGLLHEVCSQDVFGKNQPVGNHPILGENQ--TVTIKMNLSLMSRRPS-KYLKYLYRWAKERKNGIQVICEKLEFGAIPAYDPLNILKVFDAASIQELAINTRWDIYTLASLAPGVGRMKNLQKLLFKQICIPWDRPWDL--EKEACCVTEIFSQFSKLHKLQHLYLNDVYFLTERLDQMLRCFKGPLETLAITHCILSESDMMYLSQCPSTHQLKHLDLSGVTFI-LSHPFLGSLLERLTATLQTLKLKGCMLMDWQISDLLPALSQCSQLTEVNFVNNFLSMDSLKKLLQHTANLTQLTLEKYPAPDEVYDDRDGVIPDRFVRLCSELMYTLKGVRQPKQVYFVSKMFSYCWNFCIYSFVGNIEGEVIARL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2A8M8-1", "uniprot_id": "A2A8M8_MOUSE", "id": "A2A8M8-1", "name": "", "aln": "-----------------MSFKDPPTLQQLARRSLLKDEALTISALPNLPVQLFPPLFKDAFTSRHPNILRQMVAAWPFPTLPVGALME--IP-DLETLKAVLDGLDLLMSQKDRPSRWNLQVLDLRDAHQDFWDGWAGLLHEVCSQDVFGKNQPVGNHPILGEKQ--TVTIKMNLSLMSRRPS-KYLKYLYRWAKERKNGIQVICEKLEFGAIPAYDPLNILKVFDAASIQELAINTRWDIYTLASLAPGVGRMKNLQKLLFKEICIPWDRPWDV--EKEALILTEIFSQFSKLHKLQHLYLNDVYFLTERLDQMLRCFESPLETLAITHCTLSESDMRYLSQCPSTHQLKHLDLSGVTFI-LSHPFLGSLLERLTATLQTLKLKGCMLMDWQISDLLPVLSQCSQLTEVDFVKNFLSMDSLKKLLQHTANLTKLTLEKYPAPNEVYDDSDGVIPDRFVQLCSELMDTLKGVRQPKQVYFVSKMCLYCRNFCIYSFVGNI---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AGW8-1", "uniprot_id": "A2AGW8_MOUSE", "id": "A2AGW8-1", "name": "", "aln": "-----------------MSFKDPPTLQQLARRSLLKDEALTISALPNLPMQLFPPLFKDAFTNKHPNILRQMVVAWPFPTLPVGSLMK--IP-HLETLKAVLDGLDLLMSQKDRPSRWNLQVLDLRDAHKDFWDGWAGLLHEVCSQDVFGKNQPVGNHPILGGKQ--TMTIKMNLSLMSRRPS-KYLKYLYRWAKERKNGIQVICEKLEFGAIPAYDPLDVLKLCDAASIQELAINTCWDIYTLASLALGVGQMKNLQKLLFKEICISWDRPWDL--EKEARIVTEIFSEFSKLHKLQHLYLNDVYFLTERLDQMLRCFESPLETLAITHCTLSESDMSYLSQCPSIHQLKHLDLSGVTLI-LSHPFLQSLLERLTATLQTLKLKGCKLMDWQISDLLPALSQCSQLTEVDFVENFFSMDSLKKLLQNTANLTQLTLEKYPAPDEVYDDSDGVIPDRFLQLCSELIDTLKVVRQPKQVYFVSKRCLYCRNFCIYSFVGNI---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6X8-1", "uniprot_id": "A0A0G2K6X8_RAT", "id": "A0A0G2K6X8-1", "name": "", "aln": "-----------------MNFN-PPTLQHLAGRSLMKDEALAISALQDLPMQLFPPLFKDAFTSKQSNILKQMVAAWPFPCLPVGGLME--TPPHLETLKAVLDGLDLLMKQKVRLRMWKLQVLDLRDAHHDFWKGYTGIQDLVSSLDVIGKTQPVGNHPIIGGKQ--VMTVLMNLSFTSRHPS-KYIKYLCHWAKQRKNVIQVICQKLEFGAIPAYDSLNVLGVFDLGSIQELEINKCWDMCTLALLAPGLGQMKNLQKLLLKEICITVDWPWDQ--KTEGLCVKQIFFQFSKLRNLQHLYLNDVYFLNEHLDQVLRCLESPLETLAITHCMLSQSDMKYLSQCPSIHQLKHLDLSGVTFINLSHPFLRSLLERVTATLKTLKLNGCMIMDFQIRALLPVLSQCSQLTEVNFEENSLSMDSLKKLLQHTANLTHLTLEKYPAPDEVYDDTGNVIPHRFIQLCSELMDTLKILRQPNHVYFVSKKCLDCHKYFIYN--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ARR7-1", "uniprot_id": "A0A8I6ARR7_RAT", "id": "A0A8I6ARR7-1", "name": "", "aln": "---------MWENRQSTMNFNTPPTLLELGRRSLLQDEALTVSALQELPLELFPALFKDAFSSEQSIILRHMVVAWPFPCLPVGALMR--TP-HLETLKAVLGGLDLLLAQKVQPGRCKLQVLDLRDVNHNFWNVWTGMEDGVFSPDIS-HPQSLIYHPIQKGKQ--AVTVWINLSVNPRHSS-KYNEYFYQWAKERKDVVQVNCQKIEFWTNPFYDPC-LLDIVEPSSIQELEVYEHWDLETLAMLAPDLGQMINLQRLLLHNIHISLNWLGNK--EVEDYYVRMIIPLFSKLDKLQHLYLNDVCFVNEHLDQVLGCLNSPLETLVITRCKLSELDMSHLSQCPRVHQLKHLDLSGVDFINLSHEFLARLLKRLTATMQKLKLKSCMITDFQMDVLLPALSQCSQLTEVDFLMNFLSMDILKKLLQHTANLRQLTKEMYPAPCEVYDEFGNVLPHRFQQHCSDLMGTLKVIRQPKEICFMSNICAGCGEYSVYNLEAVLCSCWQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60810-1", "uniprot_id": "PRAM4_HUMAN", "id": "O60810-1", "name": "PRAME family member 4", "aln": "---------------MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWPFRRLPLRPLIK--MPCLEA-FQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMKGR--QPLTVFVELWLKNRTLD-EYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILSHMDVS----RYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1ARV6-1", "uniprot_id": "B1ARV6_MOUSE", "id": "B1ARV6-1", "name": "", "aln": "-----------------MSSKPLLTLQELAAQNILRNEALAISALQYLPELFLPQLLKQAYDGNHLKVLRAIVSSWPFPRLPLGALKKR-TPYLETQLQVVLEEVDKLLIQEVHPREYKLEVLDLRSVGQNYLNVWPGAMDD--WLPKTTQTDP--CCSKTVMT--QPLKVLVDLQLNNRGQS-RLFSYLVQWSDRRKGLLQLYCNKLQIWSPSQQNYRKLSQKVNLDYVETLGLHSSCSPSFLLNFAPYLRQMRNLRKLALSNIREE----HIISPEKRRCIITRFTLQILKLESLQKLHLDAVCFLEGHLDQLLGSVKTSLDELAVTHCNLSVSEWSHFSEFPCVSQLQQLNLENVRLTGLSPEPLQVLLVKAGPTLVALDLEDCHLEDGQLYAILPALSKCFKLTKFSFYGNQISMLAMKDLLHHTASLIHLRLELYPVPQDSYDYHGTPLMQRMQQHCDELMNLLKTFRNPGRVFFGTDRCDQCCNRYIYNKTIMCNCRRSY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M2Q6-1", "uniprot_id": "F1M2Q6_RAT", "id": "F1M2Q6-1", "name": "", "aln": "-----------------MSLQATPTLLQLAMQSLLRDEAVAISALPDLPMELFPPLFKDALTHKRSNILRRMVQVWPFPCLPLGGLMKMKAPYLDV-LQTILDGIDGLLDQNIHPSNYRLRILDLRALHKTFWTVWAGDKTASCISEAKCRRRSQRRGLETVAKP-ESLKVFIDLCLKPRALN-ACLSYVLLWARKRKALLQLGCKKLKINTIALQKNVKVLELLDLDCMEEVEVCCTWKLSTLAIFAPYLGQMKNLLSLILSHIHVP----ASISPEEKNQLVSQFTSQFPNLQCLQELSLDSACFLKGHMDQVFRCLEAPLEMLSITDSQLSESDLKALSQCPGIYQLKHLNLSGVILTNINPEPLRVLLERVAATLRILDLENCMIKDSQLSVFLPALSQCVQLIMFNYLRNPISVAALESLLLHTSKLSCLGLEMYSTPWEIFGAQSDSYHKRLDELREELSKTMMHLEHTRTVWFSVAPCLPNDNQVI----------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : . : :. .* : * . :: * *. * : * ::.:* :. .:. : :: . : . : : :: . . * * : . * :: . : . : . : * : . :* :* . . . . : :: **.: : * : .:: . .* : : : :: :*: * : .: : . * :: : *.:. * : : :: ::* : . .: .. * :. :: : : :..* : : .: :: .. * ", "identical_positions": 27, "similar_positions": 112, "identity": "5.3%" }, { "cls_id": "homologset.agr.HGNC:31972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQ-------------------------PPEQSALPTAASYFAQNESEHNGGLADASS--------------------------------------------------------------------------------LQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQNQLRLEQLQQHCQDQQSTGEQQRQQ-------YAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDES-SVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFKEASQVQPSKEETSEQKALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHEN---------------------VELQRQQLMLQQQLDRLRHYEAK-------AYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHN----------------------------HHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLP------TAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLG-------------------------------------------------------------VELPADAAQAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTEQPSHNHAGDHLNCCMGKFEVV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1IH00-1", "uniprot_id": "GOGA2_DANRE", "id": "A1IH00-1", "name": "Golgin subfamily A member 2", "aln": "---MADQNRQIKLAAAKKKLKEFQQKTIPSTGSAGPKKKRKVKGDQTDAPADRRSPENERVDVSQELEEAGAEHVSNPASAINTDNSAPQNYPADANGDEHPLENNRPLSSTESLRQLSQQLNGLLSESSTHINGDSDPPAVNEKELETRNQELSAALDSSALTNTQLTSKLETLTKQSQELSDQLQKERKEFEQKFTKEQGAMREQLQVHIQTIGILVSEKSELQTALSYTQQAARQKAAEAEDLSSRLQASKQRVSELERTLSSVSTQQKQHERHNKELEKERDSLRLEIIRFNNVSEESRQQSSELSEQLKLRVNENSALKLELEDLRKRLEMADVMLQQFSSQSGPPSEHQQLQLLLEEKHQLENHATQLMESVAQLQAERDQYAVQMQEDGRVWKDKTEQLLSQVRLMSEERDSTAAQILELQERIMELENTAAVMSTEQEPQASSQLSGPSE----TELALQETLRSLQEERDALSLQFQAQVRDNEQLSRLVQEQEVKLQELERQAERASEDAQDRLRILEDVQSDKATISRALTQNRELKDQLAELQNGFVKLTNENMELTSALQSEQHVKKEIARKMGQLQEDLHNAKEQLLESSSELTSVQEQRDQYLAHLQQYSAGYQQLLAEREHLQKQFLQQTQLMDRLQHDEVQGKVQLEQSHMQLQEVQEKLSRLVRDNEELKTEVQELLNGSIMNTSHRDEGDGLESQTLPESFQKSQIAIPEDFESREEMKEFIHSVLSRVEAERDEMSRRLEEERRIHQDTRQQLTALSHDHHHHHHHEPHSTCAETDGSEGVPVEVHEALRVAMEKLQERFTKLMQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQNQRAIMKQKHVEKEQYINMLAKDKEEMKTKLAELQDLVMRLVGERNEWYSRYMSAVGNRDLLNSNAEQIHPAERRMEISGVDAPAVLDMSTAMDVSSSPQSSTAEIQSQSSERPAADPISSPSLRPQEDGTARQIMQLLQEIQNPQSRPAPFLGENPCIPFFYRPDEHDEVKILVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A7E2F4-1", "uniprot_id": "GOG8A_HUMAN", "id": "A7E2F4-1", "name": "Golgin subfamily A member 8A", "aln": "----MLPVDGEERKSEGSDTEGDRTSPCAVSSATLKDLEVGGSGRRCSDPAGQPSNLLPQRGLGAPLPAETAHTQPS------------------------PNDRSLYLSPKSSSASSSLHARQSPCQEQA---------------------------------------------------------------------------------AVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEKKK--------------LNTDLYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEWSLCAVA---ATQKKKPDGFSSRS-KALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDAPAVSS----------------EVELQDLRKELERVAGELQAQVENNQCISLLNRGQKERLREQEERLQEQQERLRER--------------EKRLQQLAEPQSDLEELKH----------ENKSALQLEQQVK-ELQEKLGQVMETLTSAEK---------------------------------------------------------------------------EPEAAVPASGTGGESSGLMDLLEEKADLREHVEK---------------------------------------------LELGFIQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQG------------------------------GEEGEAAGAAGDGVAACGSYSEGHGKFLAAARN-PAAEPSPGAPAPQELGAADKHGDLCEASLTNS-------------------------------------------------------------------------VEPAQGEAREGSS------QDNPTAQPVVQLLGEMQDHQEHPG--LGSNCCVPCFCWAWLPRRRR----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. : : . .. . . . . ... * : . : * * :.. :. . . . . . .: .: .: : :.*: :. : :: : *: : .: :*: . .: :: *. :: : : . ... .:* :*: :. *: .* . :*..* ..::: :. : : : :* : :: :::* * * : . . :: .. :.* . : :* . : *:. . : .: : * *::: : . : : . : . : :: * * *.: :. . :: .: * * * :.:* **:: * *: *: .: *: .: ..: : * :: : : . . . .: **. .* .. : . . : *:..: .. :. . :. .: * . . :: *:::* :. . : . : . .: :.:: : : :. .:: ::: : :: . .. . * . : . ", "identical_positions": 44, "similar_positions": 223, "identity": "4.25%" }, { "cls_id": "homologset.agr.HGNC:31973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQPPEQSALPTAASYFAQNESEHNGGLADASSLQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQNQLRLEQLQQHCQDQQSTGEQQRQQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDESSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFKEAS-QVQPSKEETSEQKALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHENVELQRQQLMLQQQLDRLRHYEAKAYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHNHHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLPTAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLGVELPADAAQAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTEQPSHNHAGDHLNCCMGKFEVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8MQT2-1", "uniprot_id": "GOG8B_HUMAN", "id": "A8MQT2-1", "name": "Golgin subfamily A member 8B", "aln": "---MAEETGQSKLAAAKKKFKEYWQRN-----RPGVPAAAKRNTKANGSSP----------------ETAASGGCHSSEASSSASSSLHARQSPCQEQAAVLNSRSIKIS--------RLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEKKK-------LNTDLYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEWSLCAVA---ATQKKKPDGFSSRSKALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYAEQIK-------GERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEELERSLSR---LKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLLNRGQKERLREQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQVMETLTSAEKEPEAAVPASGTGG-ESSGLMDLLEEKADLR------EHVEKLELGFIQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQGGEEGEAAGAAGDGVAACGSYSEGHGKFLAAARN------------PAAEPSPGAPAPQELGAADKHGDLCEASLTNSVEPAQGEAREGSSQDNPTAQPVLQLLG----------------------EMQDHQEHPGLGSNCCVPCFCWAWLPRRRR----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: .*****:**:*** ** :**. .. .*:::.*: : ..:** :..* *: .::: : *. .:.:..: :: *:: :** :..:: :: * :*** : ::::* .:*: : * :: :: *:::* : : .:: :.. ::* .:*::*.*: **: .*. : : * :*..*.. ..::*. :: * : : :: :*: : :: :::* * * : ** *: ::* ::*: : :*:*.::: ..:* ***.:.: *: *: *. *: .. * : *:.** : ::: :.: :.* :.*.::*: ::. *:* :::*.. : . : :: : :*. * . ** : ::*: ::* * : **. : * : :. .. * : :*:* : . :. * :.*.. : . :* : ::: * . . .* .* . : * .. *.** * *: *:...* : . .:: *.: . *:: ..*.. : . :. : .*..*:. ::: ***:.* :* . :* :.* :*. .: * :*. ", "identical_positions": 116, "similar_positions": 261, "identity": "14.57%" }, { "cls_id": "homologset.agr.HGNC:31974", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ40-1", "uniprot_id": "NHRF3_RAT", "id": "Q9JJ40-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "aln": "MASTFNPRECKLSKKEGQNYGFFLRIEKDTDGHLVRVIEEGSPAEKAGLLDGDRVLRINGVFVDKEEHAQVVDLVRKSGNSVTLLVLDGDSYEKAVKHQVDLKELDQSPREPALNEKKPDLGMNGGVETCAQPRLCYLVKEGNSFGFSLKTIQGKKGVFLTDITPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQKTPFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQK-----GQIIKDIEPGSPAEAAGLKNNDLVVAVNGESVEALDHDGVVEMIRNGGDQTTLLVLDKEADRIYSLARFSPLLYCQSQELPNGSVKEAPAPISAPLEAPGSATTEDVGDHKPKLCRLIKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENEDIIIEVNGENVQDEPYDRVVERIKSSGEHVTLLVCGKVAYSYFQAKKIPILSSLADPLVAGPDAKGETEHDSAESTKDSSHPARDRTLSAASHSSSNSEDTVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIL4-1", "uniprot_id": "NHRF3_MOUSE", "id": "Q9JIL4-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "aln": "MASTFNPRECKLSKQEGQNYGFFLRIEKDTDGHLIRVIEEGSPAEKAGLLDGDRVLRINGVFVDKEEHAQVVELVRKSGNSVTLLVLDGDSYEKAVKNQVDLKELDQSQREAALNDKKPGPGMNGAVEPCAQPRLCYLVKEGNSFGFSLKTIQGKKGVYLTDIMPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQKTQFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQK-----GQIIKDIEPGSPAEAAGLKNNDLVVAVNGKSVEALDHDGVVEMIRKGGDQTTLLVLDKEAESIYSLARFSPLLYCQSQELPNGSVKEGPAPIPAPLEATGSEPTEDAEGHKPKLCRLLKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENEDVIIEVNGENVQEEPYDRVVERIKSSGKHVTLLVCGKMAYSYFQAKKIPIVSSMAEPLVAGPDEKGE---TSAESEHD-AHPAKDRTLSTASHSSSNSEDTEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MUH7-1", "uniprot_id": "PDZ1P_HUMAN", "id": "A8MUH7-1", "name": "Putative PDZ domain-containing protein PDZK1P1", "aln": "--------------------------------------------------------------------------------------------------------------------------MNGGVQTWTQPRLCYLVKEGGSHGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGSEQKGWGRVGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEG---IVVESKHD-SHMAKERAHSTASHSSSNSEDTEM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.*:. :***********.*.******:******::*** ******:******************:**********.*****:********* : * *** ****************:* :**************.*** *******:.***** **************:***:****.******:*****:***:***:: :* **:***:** ************.*** .:.**.... * : .******** * ::.********** ****:****:***** ****:**:****** ** :***::**:**:***::******** **.*********:**:*:** : ** * .** :* :* *::*: *:*********** *", "identical_positions": 295, "similar_positions": 66, "identity": "55.87%" }, { "cls_id": "homologset.agr.HGNC:31978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MB4-1", "uniprot_id": "ZNG1_RAT", "id": "Q99MB4-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "MLPAMKTVEAEEEYAED-CPELV-------------------------PIETKHQEKEENLD------FIIKIPVTIVTGYLGAGKTTLLNYILTEQHNRKIAVILNEFGEGSAVEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLKAIENLMQKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITVVDSKYGLKHLTEE-----------KPDGLVNEATRQVALADMILINKTDLVSE--EELNKLRTTIRSINGLGKVLETQRSRTHLSNILDLHAYDTLSGISLQKKLQHVS-TAPHLDQSIVTVTFDVPGSAEEESLN-----VFIQNLLWEKN--------VKNKDGRCMEVIRLKGLVSIK-DKPQQMIVQGIHELYELEESRVNWKDDAERACQLVFIGKNLDKDILQQLFITAVAETKEQTTAPGQ-DGACPPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEH6-1", "uniprot_id": "ZNG1_MOUSE", "id": "Q8VEH6-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "MLPAVKTVEAEEEYAED-CPELV-------------------------PIETKNQE-EENLD------FITKIPVTIVTGYLGAGKTTLLNYILTEQHNRKIAVILNEFGEGSAVEKSLAVSQGGELYEEWLELRNGCLCCSVKDSGLRAIENLMQKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITVVDSKYGLKHLTEE-----------KPDGLVNEATRQVALADMILINKTDLVSE--EELNNLRTTIRSINGLGKVLETQRSRVHLSNILDLHAYDILSGISLQKKLQHVS-TAPHLDQSIVTVTFEVPGSAKEECLN-----VFIQNLLWEKN--------VKNKDGHCMEVIRLKGLVSIK-DKPQQMIVQGIHELYDLEESLVNWKDDAERACQLVFIGRNLDKDVLQQLFLTAVAEAEEQRTAPGR-DGVCPSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V339-1", "uniprot_id": "ZNG1F_HUMAN", "id": "Q4V339-1", "name": "Zinc-regulated GTPase metalloprotein activator 1F", "aln": "MLPAVGSVDEEEDPAEEDCPELV-------------------------PIETTQSEEEEKSG------LGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKK-GKFDDILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEE-----------KPDGLINEATRQVALADIILINKTDLVPE--EDVKKLRTTLRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFDVPGNAKEEHLN-----MFIQNLLWEKN--------VRNKDNHCMEVIRLKGLVSIK-DKSQQVIVQGVHELCDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0B1-1", "uniprot_id": "ZNG1_DANRE", "id": "B0R0B1-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "-------MEDEDE-----CPELV-------------------------PIK------EKPSG------PTAQIPVTIITGYLGAGKTTLLNYILTEQHNKRIAVILNEFGEGSALEKSLAVSQAGELYEEWLELRNGCLCCSVKDNGLKAIENLMEKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDVYLDGIVTVIDAKYGLQHLTEE-----------KPEGLINEAARQIALADLTIINKTDLVHE--TELLKLRDTVRSINALVKILETQKSRVDLSEVLDLHSFDTKDGERLTKKLQLVKTSQPHLDKSMLTITFEVPGSVSEDLLN-----IFIQELLWEKT--------FKNKAGLPMTVIRLKGILSLQ-QKQKKVMLQGVHELYELEETPEFWADQEPRLNRLVFIGRNLDGEILKKEFISAVSNKDSVE-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53729-1", "uniprot_id": "ZNG1_YEAST", "id": "P53729-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "-MSALRNIKFNEEEDGE-LPCLVTGEENNLQEILENVSYDGGNIVSDAKVERVNKQVENTSAGATDVHEKKRIPVSIITGYLGSGKSTLLEKIALKGADKKIAVILNEFGDSSEIEKAMTIKNGSNSYQEWLDLGNGCLCCSLKNIGVKAIEDMVERSPGKIDYILLETSGIADPAPIAKMFWQDEGLNSSVYIDGIITVLDCEHILKCLDDISIDAHWHGDKVGLEGNLTIAHFQLAMADRIIMNKYDTIEHSPEMVKQLKERVREINSIAPMFFTKYSDTPIQNLLDIHAYDS---VRISDILDSGSGNGTIHDDRMGTIMLTFRPLKNEEEYNNKFIKQFLQPLLWKNFGAMTVLGGRRRDDGRDWEVQRTKGLILIEGENPIARVIQGVRDTYDVFPG---KYDGSNKECKIVLIGKYLEKESIEELLRKTLE-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ::: * ** :: *: :***:*:*****:**:***: * : .:::****** *:.* :**::::.:..: *:***:* *******:*: *::***:::::. **:* *****:*:***..:*.*** * *.*.:*:***:*::*.:: *: * : :* :. * *:*:** ::** * : . : :*: :*.**.: :: *: * . :.::**:*::* : . *: . . *. : *: : . .*: * *:* ***:: :.. . * * **:: :: :: ::**::: :: * : ::*:**: *: : ::: : :: ", "identical_positions": 113, "similar_positions": 134, "identity": "24.78%" }, { "cls_id": "homologset.agr.HGNC:31984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BS95-1", "uniprot_id": "GPHR_MOUSE", "id": "Q8BS95-1", "name": "Golgi pH regulator", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKLNLCVILLILVFMVPFYIGYFIVSNIQ--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAVARRTMFQR---GDVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LTD0-1", "uniprot_id": "F1LTD0_RAT", "id": "F1LTD0-1", "name": "", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIQ--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAVTRRTMFQR---GDVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7ZAQ6-1", "uniprot_id": "GPHRA_HUMAN", "id": "B7ZAQ6-1", "name": "Golgi pH regulator A", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIR--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAMARRTMFQK---GEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB29-1", "uniprot_id": "E7FB29_DANRE", "id": "E7FB29-1", "name": "", "aln": "MSFFVDSVIMFTS---------QVLFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVVFSITFAFSCTMFELIIFEILGALSSS--------SRYFHWKLNLYVILLVLIFVVPFYIGYFVVSNIR--LLQRQRLLFSCVVWFTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDSDILALERR-----------LLQTMDMIVSKKKR---IAMTRRQMYQR---GEEQNKQTGFWGMIKSVTSSPSGSENLSLIQQEVDALEELSRQLFLETVDLQATKERIEYSKTFQGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLVLAQIMGMYFVSSVLLMRMSMPLEYRSIVSEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38799-1", "uniprot_id": "YHN8_YEAST", "id": "P38799-1", "name": "Uncharacterized protein YHR078W", "aln": "MEALIVFIVLSVSGAFAYKCSYERLWFKVGSLFDIISTSSKKNVIPLASKMEVGSNEDVSSMGNFINKFYTEYSLPSHKVLQSLRVLFSLAMMTYTVTIEIILWQIKVAGMDKEVTFITTWVWPLTAIMLSFILILFQPFFIIISLLNKFYNDKFDIDRLIIVTCIILSTLIALLSYINIGPFQYTKN-------ILTRLSIGGVTVMASLSGLATVSSLYYNFLVIWHKFRNTPMSDPSFRNINNSNNNSKSLLWTTDAYIEEKIQDYEHNIEQNVQILRSLEEEVGENSTFKAELMEKIAWYQLELGKLEALLQQSPQVRTFKKAFEVGFIIYCLHKLIITFLKRIPYIIYHSLKYPDDYDYENFSENAASDPLAITIANILDFSFFRFNYQHDLDSLTKQISLFLSISLFLCCLSAVNTTISYVVTLLPIKFQILALFAMQNDDTANVLPEYTNNSSYKGKKRNYSQEQKGISLIKNLVVSELTGVYVLATTLMVRSHLPFEVSQRLKELLGGKFTVPNIVIDSWFDEVYAFACVFTFICIRIAERKLSTKKVSVE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: :: .* : *:* .* ** *:.:::.:*.: .: * : : *::: : : * ** :. : : * :. :: ::*::. **:* ::.:: :. :**:: : :: : : . : *: .*: :::*:.: ***:** ***:.:*.. * : : ::. :: : . * ** * * :.:* : : :. : : :: : :::.:: :* : *: :. :.: : : * * : * : :: * * ** .. . : ** ::* :.:: .: :.: :.:.:: :* : . * *.:: : : : :* ....: * : *::::: *:*.:::.*::* :* * :.*:** : . . *** :: .:.: ::: : :*.:: . *::: ", "identical_positions": 72, "similar_positions": 189, "identity": "12.88%" }, { "cls_id": "homologset.agr.HGNC:31986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60688-1", "uniprot_id": "FOXD4_MOUSE", "id": "Q60688-1", "name": "Forkhead box protein D4", "aln": "MNSARAGHLRSTPPPSPLSSDQ---DEVEIDVLAEEEDGDQTEEEDDEEESHKCLERSLQ------RPGARTLAGRSAGDCGDLSNSSGFLRKFRAPRTPATTTADGPQPAKPPYSYIALIT----MAILQSPHKRLTLSGICAFISGRFPYYRR------------KFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHHPPSGGHPHCPF----------PPPAVPATLHVS------------QPSLLLRYSAPPQPNLAAHPAAPP----RSHPCAPLHPHPMR------YLLLAAPAY-------GDNPRKAEGADPATPLAIPALQPVLGS-QPWERD-QSSGTRSGRGCASFTIESIMQGVTGGGTGSAQSPSFAPWSYCHLLQHPPCLLHPQAASPLFHMSAGSR-TILPQQPQPPLPLQQEQHHCAISCAPGKGVRLGQHLSAVAALLRQQPAADDGRLTTLAALSGREGTLPEF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63249-1", "uniprot_id": "FOXD4_RAT", "id": "Q63249-1", "name": "Forkhead box protein D4", "aln": "-------------------------------------------------------------------------------------------------------------PAKPPYSYIALIT----MAILQSPHKRLTLSGICAFISGRFPYYRR------------KFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3SYB3-1", "uniprot_id": "FX4L6_HUMAN", "id": "Q3SYB3-1", "name": "Forkhead box protein D4-like 6", "aln": "MNLPRAERLRSTPQRSLRDSDG---EDGKIDVLGEEEDEDEVEDEE-EAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALIT----MAILQNPHKRLTLSGICAFISGRFPYYRR------------KFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPF----------PLPAAHAALHNP------------HPGPLLGAPAPPQPVPGAYPNTAP----GRRPYALLHPHPLR------YLLLSAPVY-------AGAPKKAEGAALATPAPFPCCSPHLVL-SLGRRA-RVWR-RHREADASLSALRVL--CKGSGERVQGLRRVCPR--------------PRGATATCS-SDHQA-CCIPR----PLPL-------CCKCPPPP--LLGQFCSNSSS-IRRRTAPTAALPPRARCWAGTCRPRRPC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02361-1", "uniprot_id": "FD3_DROME", "id": "Q02361-1", "name": "Fork head domain-containing protein FD3", "aln": "MHTS------TDPMHTLHDS-----VSLSPPLIKSSRGGSSIGNGIGCSASSR----------------TAAADAMSMGCDDSDIEPSSMGGSGAAGGNGDGSGSSGGPLVKPPYSYIALIT----MAILQSPHKKLTLSGICDFIMSRFPYYKD------------KFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPLVPVHFNVPNFNGSREFDVVHNPADVFDSALRADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDVATVASAAGIPGHRD-YAERLSAGGGYMDLNVYNDDADTEADAEAEGDDDSCEDKIDVE----------SGNEQEDSHISDSVDSACTNRLDAPPEALIFEASAEASDSSPRRRFDSEPLVLRTSKQSSAKDFRIETLIGHHLHRGGSQEETSD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNN-----NPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLS----------SSSDVNPIGDP------------HGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENP--SDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : * : : *: ::.: * . . : : . *::* : .**. : *: * *:. :* .::::..::**.:: :. ", "identical_positions": 14, "similar_positions": 38, "identity": "2.73%" }, { "cls_id": "homologset.agr.HGNC:32", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESR9-1", "uniprot_id": "ABCA2_RAT", "id": "Q9ESR9-1", "name": "ATP-binding cassette sub-family A member 2", "aln": "MGFLHQLQLLLWKNVTLKRRSPWVLAFEIFIPLVLFFILLGLRQKKPTISVKEAFYTAAPLTSAGILPVMQSLCPDGQRDEFGFLQYANSTVTQLLERLNRVVEESNLFDPERPSLGSELEALHQRLEALSSGPGTWESHSARPAVSSFSLDSVARDKRELWRFLMQNLSLPNSTAQALLAARVDPSEVYRLLFGPLPDLDGK-----LGFLRKQEP--------------WSHLGS----------------------------------------NPLFQMEELLLAPALLEQLTCAPG-SGELGRILTMPEGHQVDLQGYRDAVCSGQATARAQHFSDLATELRNQLDIAKIAQQLGFNVPNGSDPQPQAPSPQSLQALLGDLLDVQKVLQDVDVLSALALLLPQGACAGRAPAPQAGSPSGPANSTGVGANTGPNTTVEEGTQSPVTPASPDTLQGQCSAFVQLWAGLQPILCGNNRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHLMTSNPKILYAPAGSEADHVILKANETFAFVGNVTHYAQVWLNISAEIRSFLEQGRLQQHLHWLQQYVADLRLHPEAMNLSLDELPPALRLDYFSLPNGTALLQQLDTIDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQDNVTVFASVIFQTRKDGSLPPHVHYKIRQNSSFTEKTNEIRRAYWRPGPNTGGRFYFLYGFVWIQDMIERAIINTFVGHDVVEPGNYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMKTMGLNNAVHWVAWFITGFVQLSISVTALTAILKYGQVLMHSHVLIIWLFLAVYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLG-SKYFALYEVAGVGIQWHTFSQSPVEGDDFNLLLAVTMLMVDTVVYGVLTWYIEAVHPGMYGLPRPWYFPLQKSYWLGSGRTETWEWSWPWAHAPRLSVMEEDQACAMESRHFEETRGMEEEPTHLPLVVCVDKLTKVYKNDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDQLTVEEHLWFYSRLKSMAQEEIRKEMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGAYGDGYRLTLVKRPAEPGTSQEPGMASSPSGRPQLSNCSEMQVSQFIRKHVASSLLVSDTSTELSYILPSEAVKKGAFERLFQQLEHSLDALHLSSFGLMDTTLEEVFLKVSEEDQSLENSEADVKESRKDALPG---------------AEGLTAVESQAGNLARCSELAQSQASLQSASSVGSARGDEGAGYTDGYGDYRPLFDNLQDPDSVSLQEAEMEALARVG--QGSRKLEGWWLKMRQFHGLLVKRFHCARRNSKALCSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQPRGNFIPYANEERREYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPAN---GSLGPMLNLSSGESRLLAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPLSPDEDSLLAWNTSLPPTAGPETWTWAPSLPRLVHEPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTGDILTDITGHNVSEYLLFTSDRFRLHRYGAITFGNIQKSIPAPIGTRTPLMVRKIAVRRVAQVLYNNKGYHSMPTYLNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFIIVAMSFVPASFVVFLVAEKSTKAKHLQFVSGCNPVIYWLANYVWDMLNYLVPATCCIIILFVFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLLQLFEHDKDLKVVNSYLKSCFLIFPNYNLGHGLMEIAYNEYINEYYAKIGQFDKMKSPFEWDIVTRGLVAMTVEGFVGFFLTIMCQYNFLRQPQRLPVSTKPVEDD-VDVASERQRVLRGDADNDMVKIENLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKDLLQVQQSLGYCPQFDALFDELTAREHLQLYTRLRGIPWKDEAQVVRWALEKLELTKCADKPAGSYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEAVCTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKSSQNVKDVVRFFNRNFPEAMLKERHHTKVQYQLKSEHISLAQVFSKMEHVVGVLGIEDYSVSQTTLDNVFVNFAKKQSDNVEQQEAEP-STLPSPLG-LLSLLRPRPAPTELRALVADEPEDLDTED-EGLISFEEERAQLSFNTDTLC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41234-1", "uniprot_id": "ABCA2_MOUSE", "id": "P41234-1", "name": "ATP-binding cassette sub-family A member 2", "aln": "MGFLHQLQLLLWKNVTLKRRSPWVLAFEIFIPLVLFFILLGLRQKKPTISVKEAFYTAAPLTSAGILPVMQSLCPDGQRDEFGFLQYANSTVTQLLERLHRVVEEGNLFDPVRPSLGSELEALRQRLEALSSGPGTWESHSARPAVSSFSLDSVARDQRELWRFLMQNLSLPNSTAQALLAARVDPSEVYRLLFGPLPDLDGK-----LGFLRKQEP--------------WSRLGS----------------------------------------NPLLQMEELLLAPALLEQLTCAPG-SGELGRILTMPEGHQVDLQGYRDAVCSGQATARAQRFSDLAAELRNQLDTAKIAQQLGFDVPNGSDPQPQAPSPQSLPALLGDLLDAQKLLQDVDVLSALALLLPQGACAGQASAPQASSLNGLANSTGIGANSGSNTTVEEGTQSPVSPASPDTLQGQCSAFVQLWAGLQPILCGNNRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHLMTSNPKILYAPVGSEADRVILKANETFAFVGNVTHYAQVWLNISTEIRSFLEQGRLQQHLQWLQQYVADLQLHPEAMNLSLEELPPALRQD-FSLPNGTALLQQLDTIDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQDNVTVFASVIFQTRKDGSLPPHVHYKIRQNSSFTEKTNEIRRAYWRPGPNTGGRFYFLYGLRLDQDMMERAIINTFVGHDVVEPGNYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMKTMGLNNAVHWVAWFITGFVQLSISVTALTAILKYCQVLMHSHVLIIWLFLAVYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASRCPQQPLAWVPSTLHCMKWQEWASIQWHTFSQSPVEGDDFNLLLAVTMLMVDTVVYGVLTWYIEAVHPGMYGLPRPWYSRYRSPIGWAVGGQKPGSGAGHGHTHRASALWRRIQACAMESRHFEETRGMEEEPTHLPLVVCVDKLTKVYKNDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRKETDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGAYGDGYRLTLVKQPAEPGTSQEPGLASSPSGCPRLSSCSEPQVSQFIRKHVASSLLVSDTSTELSYILPSEAVKKGAFERLFQQLEHSLDALHLSSFGLMDTTLEEVFLKVSEEDQSLENSEADVKESRKDVLPG---------------AEGLTAVGGQAGNLARCSELAQSQASLQSASSVGSARGEEGTGYSDGYGDYRPLFDNLQDPDNVSLQEAEMEALAQVG--QGSRKLEGWWLKMRQFHGLLVKRFHCARRNSKALCSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQPRGNFIPYANEERQEYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPAN---GSLGPMLNLSSGESRLLAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPVSPDEDSLQAWNMSLPPTAGPETWTSAPSLPRLVHEPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTGDILTDITGHNVSEYLLFTSDRFRLHRYGAITFGNVQKSIPASFGARVPPMVRKIAVRRVAQVLYNNKGYHSMPTYLNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFIIVAMSFVPASFVVFLVAEKSTKAKHLQFVSGCNPVIYWLANYVWDMLNYLVPATCCVIILFVFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLLQLFEHDKDLKVVNSYLKSCFLIFPNYNLGHGLMEMAYNEYINEYYAKIGQFDKMKSPFEWDIVTRGLVAMTVEGFVGFFLTIMCQYNFLRQPQRLPVSTKPVEDD-VDVASERQRVLRGDADNDMVKIENLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKDLLQVQQSLGYCPQFDALFDELTAREHLQLYTRLRGIPWKDEAQVVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKSSQNVKDVVRFFNRNFPEAMLKERHHTKVQYQLKSEHISLAQVFSKMEQVVGVLGIEDYSVSQTTLDNVFVNFAKKQSDNVEQQEAEP-SSLPSPLG-LLSLLRPRPAPTELRALVADEPEDLDTED-EGLISFEEERAQLSFNTDTLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZC7-1", "uniprot_id": "ABCA2_HUMAN", "id": "Q9BZC7-1", "name": "ATP-binding cassette sub-family A member 2", "aln": "MGFLHQLQLLLWKNVTLKRRSPWVLAFEIFIPLVLFFILLGLRQKKPTISVKEAFYTAAPLTSAGILPVMQSLCPDGQRDEFGFLQYANSTVTQLLERLDRVVEEGNLFDPARPSLGSELEALRQHLEALSAGPGTSGSHLDRSTVSSFSLDSVARNPQELWRFLTQNLSLPNSTAQALLAARVDPPEVYHLLFGPSSALDSQ-----SGLHKGQEP--------------WSRLGG----------------------------------------NPLFRMEELLLAPALLEQLTCTPG-SGELGRILTVPESQKGALQGYRDAVCSGQAAARARRFSGLSAELRNQLDVAKVSQQLGLDAPNGSDSSPQAPPPRRLQALLGDLLDAQKVLQDVDVLSALALLLPQGACTGRTPGPPASGAGGAANGTGAGAVMGPNATAEEGAPSAAALATPDTLQGQCSAFVQLWAGLQPILCGNNRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHLMTSNPKILYAPAGSEVDRVILKANETFAFVGNVTHYAQVWLNISAEIRSFLEQGRLQQHLRWLQQYVAELRLHPEALNLSLDELPPALRQDNFSLPSGMALLQQLDTIDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQDNVTVFASVIFQTRKDGSLPPHVHYKIRQNSSFTEKTNEIRRAYWRPGPNTGGRFYFLYGFVWIQDMMERAIIDTFVGHDVVEPGSYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMKTMGLNNAVHWVAWFITGFVQLSISVTALTAILKYGQVLMHSHVVIIWLFLAVYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLG-SKYFALYEVAGVGIQWHTFSQSPVEGDDFNLLLAVTMLMVDAVVYGILTWYIEAVHPGMYGLPRPWYFPLQKSYWLGSGRTEAWEWSWPWARTPRLSVMEEDQACAMESRRFEETRGMEEEPTHLPLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGTYGDGYRLTLVKRPAEPGGPQEPGLASSPPGRAPLSSCSELQVSQFIRKHVASCLLVSDTSTELSYILPSEAAKKGAFERLFQHLERSLDALHLSSFGLMDTTLEEVFLKVSEEDQSLENSEADVKESRKDVLPG---------------AEGPASGEGHAGNLARCSELTQSQASLQSASSVGSARGDEGAGYTDVYGDYRPLFDNPQDPDNVSLQEVEAEALSRVG--QGSRKLDGGWLKVRQFHGLLVKRFHCARRNSKALFSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQPRGNFIPYANEERREYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPAN---GSLGPTLNLSSGESRLLAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPASPDED-LQAWNVSLPPTAGPEMWTSAPSLPRLVREPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTGDILTDITGHNVSEYLLFTSDRFRLHRYGAITFGNVLKSIPASFGTRAPPMVRKIAVRRAAQVFYNNKGYHSMPTYLNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFIIVAMSFVPASFVVFLVAEKSTKAKHLQFVSGCNPIIYWLANYVWDMLNYLVPATCCVIILFVFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLLQLFEHDKDLKVVNSYLKSCFLIFPNYNLGHGLMEMAYNEYINEYYAKIGQFDKMKSPFEWDIVTRGLVAMAVEGVVGFLLTIMCQYNFLRRPQRMPVSTKPVEDD-VDVASERQRVLRGDADNDMVKIENLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKDEARVVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKSSQSVKDVVRFFNRNFPEAMLKERHHTKVQYQLKSEHISLAQVFSKMEQVSGVLGIEDYSVSQTTLDNVFVNFAKKQSDNLEQQETEPPSALQSPLGCLLSLLRPRSAPTELRALVADEPEDLDTED-EGLISFEEERAQLSFNTDTLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCJ8-1", "uniprot_id": "A0A8M2BCJ8_DANRE", "id": "A0A8M2BCJ8-1", "name": "ATP-binding cassette sub-family A member 2", "aln": "MGFLHQLHLLLWKNVTLKRRGPWVLAFEIFIPLVLFFILLGLRQKKPAIPVKEAFYSAAPLTSAGIIPIMQSLCPDGQRDEFGFLQYKNSTVTQLLERISEVVEQNHLFTSDRPSLGEELESLQQHLESLSSAQGPLESHYN--TSHGFTVGSVLRNQSMFQQFLIRNLSLPNDTSSLLLSSPVNLKEVYNLIFGTYPKAGSKGGERDEGQHQLNSPGEKLVQLEKQLLGGWHSLDGGLIQKALRDPTKAAHRQALLKVFSQALGIAGGVGGQKFDPQALREMEGVLLTGAVLESLTCGEGGNSEIGKILLVPEKQQAVLQAYRTTVCGLGAGQRAELFRQLSEELRDQIDTQRVFDQLRLEQSNMSGLLDQS----RLGALLKNLADVERLLRDVDLLSGLARLLPKGACAGHQPPPQANTTSWSSNTTTWGPNT-TDSSLEEGVGASESEAEAENPKSQFSAFVQLWAGLQPILCGNNRIFEPEALKQGNMSSLGFTSKEQRNLGLLVHLMTTNPKILYSPIDSEVDKVIQKANETFAFVGNVTHYARVWLNISAELRAFLEEGKLQNHLMWLQQFITDLKRHHELLNVSDSELMNSLLEENFTLPNTTTLLEQLHTIDNAACGWTNFMSKVSVDIFRGFPDEESIVNYTLNQAYHDNVSVFASVIFQTNKDGSLPPHVMYKIRQNSSFTEKTNEIRRAYWRPGPNTGGKFYFLYGFVWIQDMIERAIINTFVGHDVVEPGNYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMMIQHIVAEKEQRLKEVMKMMGLNNAVHWVAWFITGFVQLSISVTALTAILKYGKVLLHSDPFIIWLFLTIYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLG-SKYFALYEVAGVGIQWRTINQSPVEGDDFNLLLSMVMLTIDAIVYGVLTWYIEAVHPGMYGLPRPWYFPLQKSYWLGSGRIETWEWPWGGG--TRLSVMEEDQACAMEHRRSEETRGIEEEPNHLPLVVCIDKLTKVYKTGSKLALNKLSLNLHENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMERIRQNLGMCPQHNVLFDKLSVEEHLWFYSRLKGMAEEDIRKEMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVGGSRAVILDEPTAGVDPYARRAIWDLILKYKQGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKSTYGDGYKLTLVKKQSDSHTADQ----SSQSPSSSISPCSENRVTQFIRQYVASCLLVSDSNTELSYVLPSEAVKKGCFERLFQALEQSLDSLALTSFGVMDTTLEEVFLKVSEEDLSLENSDADMKDSPGGASAGKPSGLLGGPQCEGAPAAAVMRPEVELSNLMMCSRLSPSQASLQSGSSLGSVRGDEGGPYSEFYGDYCPLFDNGQDLDSASLRDEESSPQPTVLEGQGSFKLDGWWLKLRQFHGLIVKRFHCAKRNTKGIFSQILLPAFFVCVAMTVALSVPEIGDLPPLILSPSQYHNYTQPRGNFIPYANEDRSQYRTKFSPDAGPQRIVNTLRLPSGVGATCILKTPFNSTLDQLAQTLNPYANNSKTLAARYFDSMCLDSFTQGVPLSNFVPPPPSPAPSDDPEAHFED--GLWNYTAAPTTVREMATSPPTLPLSIHEPVRCICSMQGTGFSCPSGVGGRPPLMKVVTGDILVDITGRNVSEYLLYTSDRLRLHRYGGFTVGNIQKSVPASFGRKTPPMVRKIAVRRSSQVLYNNKGYHSMPTYLNVLNNAILRANLPSSKGNPSAYGITVTNHPMNRTSASLSLDYLLQGTDVVIAIFIIVAMSFVPASFVVFLVAEKSTKAKHLQFVSGCDPVTYWLANYIWDMLNYLVPATCCVLILFVFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSTAYVFLIVINLFIGITATVATFLLQLFERDKDLKLVNSYLKSCFLIFPNYNLGHGLMEMAYNEYINEYYAKIGQFDKVKSPFEWDIVTRGLVAMTIEGFVGFLITILCQYNFLRKAQRVPVNSQPVEDDDVDVACERRRVLRGDADNDMLKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIQEHSILRELLRVQQSIGYCPQFDALFDDLTAREHLELYTRLRGIPWKDEERVVQWALEKLELSKYADKPAGTYSGGNKRKLSTAIALIGYPSLIFLDEPTTGMDPKARRFLWNLILDIIKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNRFGDGYMITVRTKTTASVKEVIRFFNRNFPEAILKERHHTKIQYQLKSENISLAQVFSKMEQVVEVLSIEDYSVSQTTLDNVFVNFAKKQSDNLEQQESSPSSGGQSPLQHLLSLLRPRPANTELNALVSEEPEELESDDDEGLISFEEERVQLSFNTDTLC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:************.**************************:*.******:*********:*:****************** **********: .***:.:** . *****.***:*:*:**:**:. *. ** : .*::.** *: : :** :******.*:. **:: *: ***.*:**. . ..: * : :.* * *.. :.* .** :**: *:**.*** * ..*:*:** :** :: **.** :**. * **. * *: ***:*:* :: :** :: .* *. *: * *** :* *.:::*:***:**.** ***:***:*: . * *. . :* * *. .::: ***. :. : * .:. :.* ******************* :*****::************************:******:* .**.*:** ****************:******:*:*:***:*:**:** ****::::*: * * :*:* .** :* : *:**. :**:**.********* :**********:*****************:***:*********.********* *****************************:******: ***:*****:***********.************************************* *********:******* ********************************* :**:**. .******::************************************************************ . .:. *. ..: ..***:*:.*************::.** :*::***:******************** :.. . * :. . . :: .. ****** *: *****:****.*******:******** ..***********:********************************************:.**:*************:*:************.**:*:**:* ****************************************:************************* ***************************************.:*****:*****: ::. .:: ** . . :* *** :*:****::***.*****:.*****:*****.***.****** **:***:* *:***:**************** *****:**:*:* .. .* * . . .** **.*: *******.**:**.**:** *:: **** ***** ** *..**:: * .. . * *** **:* ***:******:*******:**:*.: *****************************:**********************:* :** ::****.**::*.*:**********:**:* * ..*. ** :.:*: ****:******:*****:****************.* : ** ** : .**: * * .*:** ::***** ** *********.***:** *:*******.****:*******:****:******.:*.**: **:**.:* :.* ********* :**:************** ***********.*****:************:******************************************************:*: ******:*************::*********************************************:***************************:*****:***********************:******************:****************::**.***::**:*******:.**:**.::***** ****.**:***********:**:**********:******************************:*****************:: **:*::**:****:***** *****:*******:********.**** :**:********:* ******:*******************::************************:*******************:****.******::***********************:: .**:*:**********:********:*******:***********:* **.*************************:****:.* * *** ********.* ***.***::***:*:::* **********.**********", "identical_positions": 1810, "similar_positions": 383, "identity": "71.85%" }, { "cls_id": "homologset.agr.HGNC:320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62151-1", "uniprot_id": "RAGE_MOUSE", "id": "Q62151-1", "name": "Advanced glycation end product-specific receptor", "aln": "MPAGTAARAWVLVLALWGAVAGGQNITARIGEPLVLSCKGAPKKPPQQLEWKLNTGRTEAWKVLSPQGG-PWDSVARILPNGSLLLPATGIVDEGTFRCRATNRRGKEVKSNYRVRVYQIPGKPEIVDPASELTASVPNKVGTCVSEGSYPAGTLSWHLDGKLLIPDGKETLVKEETRRHPETGLFTLRSELTVIPTQGG-THPTFSCSFSLGLPRRRPLNTAPIQLRVREPGPPEGIQLLVEPEGGIVAPGGTVTLTCAISAQPPPQVHWIKDGAPLPLAPSPVLLLPEVGHEDEGTYSCVATHPSHGPQESPPVSIRVTETGDEGPAEGSVGESGLGTLALALGILGGLGVVALLVGAILWRKRQPRREERKAPESQEDEEERAELNQSEEAEMPENGAGGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63495-1", "uniprot_id": "RAGE_RAT", "id": "Q63495-1", "name": "Advanced glycation end product-specific receptor", "aln": "MPTGTVARAWVLVLALWGAVAGGQNITARIGEPLMLSCKGAPKKPTQKLEWKLNTGRTEAWKVLSPQGD-PWDSVARILPNGSLLLPAIGIVDEGTFRCRATNRLGKEVKSNYRVRVYQIPGKPEIVNPASELTANVPNKVGTCVSEGSYPAGTLSWHLDGKPLIPDGKGTVVKEETRRHPETGLFTLRSELTVTPAQGG-TTPTYSCSFSLGLPRRRPLNTAPIQPRVREPLPPEGIQLLVEPEGGTVAPGGTVTLTCAISAQPPPQIHWIKDGTPLPLAPSPVLLLPEVGHEDEGIYSCVATHPSHGPQESPPVNIRVTETGDEGQAAGSVDGSGLGTLALALGILGGLGIAALLIGAILWRKRQPRLEERKAPESQEDEEERAELNQSEEAEMPENGAGGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15109-1", "uniprot_id": "RAGE_HUMAN", "id": "Q15109-1", "name": "Advanced glycation end product-specific receptor", "aln": "MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGVILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:**.. ******:*****.*.***********:*.********.*:********************. *******:******:*** ** *** ***:* ** ***.******************:.******.************************** *:*: * . ***:************:*** * *::** . **:***** ****:*.*.***** ** ** * * :**:****** *********** :.***.**:**:***.****.*****:***:* :*:* *******.******* .*.* : *.*:** : ***. ***************** .***:*.***::** * *******.**:************.* *..:***", "identical_positions": 305, "similar_positions": 63, "identity": "75.5%" }, { "cls_id": "homologset.agr.HGNC:3200", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10126-1", "uniprot_id": "EF1A1_MOUSE", "id": "P10126-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKG-------------SFKY-----------------------AWVLDKLKAERERGITIDISLWKFETS-------KYYVTIIDA---------PGHRDFIKN--MITGTSQADCAVLIVAAG----------------------------------------------------------VGEFEAGISKNG-----------------------------QTREHALLAYTLGVK--------QLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIG-----------------YNPDTVAFVPIS----GWNGDNMLEPSANMPWFKGWKVTR----------------------------KDGSASGTTLLEALDCILPP---TRPTDKPLRLP----------LQDVYKIGGIGTVPVG-------------------RVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALS-----EALPGDNVGFNVKNVSVKDVR--------RGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAG--------------YAPVLDCHTAHIACKFAELKE--------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62630-1", "uniprot_id": "EF1A1_RAT", "id": "P62630-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKG-------------SFKY-----------------------AWVLDKLKAERERGITIDISLWKFETS-------KYYVTIIDA---------PGHRDFIKN--MITGTSQADCAVLIVAAG----------------------------------------------------------VGEFEAGISKNG-----------------------------QTREHALLAYTLGVK--------QLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIG-----------------YNPDTVAFVPIS----GWNGDNMLEPSANMPWFKGWKVTR----------------------------KDGSASGTTLLEALDCILPP---TRPTDKPLRLP----------LQDVYKIGGIGTVPVG-------------------RVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALS-----EALPGDNVGFNVKNVSVKDVR--------RGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAG--------------YAPVLDCHTAHIACKFAELKE--------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VTE0-1", "uniprot_id": "EF1A3_HUMAN", "id": "Q5VTE0-1", "name": "Putative elongation factor 1-alpha-like 3", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKG-------------SFKY-----------------------AWVLDKLKAERERGITIDISLWKFETS-------KYYVTIIDA---------PGHRDFIKN--MITGTSQADCAVLIVAAG----------------------------------------------------------VGEFEAGISKNG-----------------------------QTREHALLAYTLGVK--------QLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIG-----------------YNPDTVAFVPIS----GWNGDNMLEPSANMPWFKGWKVTR----------------------------KDGNASGTTLLEALDCILPP---TRPTDKPLRLP----------LQDVYKIGGIGTVPVG-------------------RVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALS-----EALPGDNVGFKVKNVSVKDVR--------RGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAG--------------YAPVLDCHMAHIACKFAELKE--------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05303-1", "uniprot_id": "EF1A2_DROME", "id": "P05303-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKG-------------SFKY-----------------------AWVLDKLKAERERGITIDIALWKFETS-------KYYVTIIDA---------PGHRDFIKN--MITGTSQADCAVLIVAAG----------------------------------------------------------TGEFEAGISKNG-----------------------------QTREHALLAFTLGVK--------QLIVGVNKMDSTEPPYSEARYEEIKKEVSSYIKKIG-----------------YNPASVAFVPIS----GWHGDNMLEPSEKMPWFKGWSVER----------------------------KEGKAEGKCLIDALDAILPP---QRPTDKPLRLP----------LQDVYKIGGIGTVPVG-------------------RVETGLLKPGMVVNFAPVNLVTEVKSVEMHHEALT-----EAMPGDNVGFNVKNVSVKELR--------RGYVAGDSKNNPPRGAADFTAQVIVLNHPGQIANG--------------YTPVLDCHTAHIACKFSEIKE--------------------------KCDRRTGKTTETEPKAIK---------------------SGDAAIIVLVPSKPLCVESFQEFP------------------PLGRFAVRDMRQTVAVGVIKSVNFKETTSGKVTKAAEKAQKKK-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08736-1", "uniprot_id": "EF1A1_DROME", "id": "P08736-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKG-------------SFKY-----------------------AWVLDKLKAERERGITIDIALWKFETA-------KYYVTIIDA---------PGHRDFIKN--MITGTSQADCAVLIVAAG----------------------------------------------------------TGEFEAGISKNG-----------------------------QTREHALLAFTLGVK--------QLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIG-----------------YNPAAVAFVPIS----GWHGDNMLEPSTNMPWFKGWKVER----------------------------KEGNADGKTLIDALDAILPP---ARPTDKALRLP----------LQDVYKIGGIGTVPVG-------------------RVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQ-----EAVPGDNVGFNVKNVSVKELR--------RGYVAGDSKANPPKGAADFTAQVIVLNHPGQIANG--------------YTPVLDCHTAHIACKFAEIKE--------------------------KVDRRSGKTTEENPKFIK---------------------SGDAAIVNLVPSKPLCVEAFQEFP------------------PLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAAEKATKGKK------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02994-1", "uniprot_id": "EF1A_YEAST", "id": "P02994-1", "name": "Elongation factor 1-alpha", "aln": "--------------MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKG-------------SFKY-----------------------AWVLDKLKAERERGITIDIALWKFETP-------KYQVTVIDA---------PGHRDFIKN--MITGTSQADCAILIIAGG----------------------------------------------------------VGEFEAGISKDG-----------------------------QTREHALLAFTLGVR--------QLIVAVNKMDSVK--WDESRFQEIVKETSNFIKKVG-----------------YNPKTVPFVPIS----GWNGDNMIEATTNAPWYKGWEKET----------------------------KAGVVKGKTLLEAIDAIEQP---SRPTDKPLRLP----------LQDVYKIGGIGTVPVG-------------------RVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLE-----QGVPGDNVGFNVKNVSVKEIR--------RGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAG--------------YSPVLDCHTAHIACRFDELLE--------------------------KNDRRSGKKLEDHPKFLK---------------------SGDAALVKFVPSKPMCVEAFSEYP------------------PLGRFAVRDMRQTVAVGVIKSVDKTEK-AAKVTKAAQKAAKK--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O88943-1", "uniprot_id": "KCNQ2_RAT", "id": "O88943-1", "name": "Potassium voltage-gated channel subfamily KQT member 2", "aln": "MVQKSRNGGVYPGTSGEKKLKVGFVGLDPG-APDSTRDGALLIAGSEAPKRGSVLSKPRTGGAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSRDHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLVRIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVAWAGPRK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::* ::..* :. : .** * *: . ** : .: * * .* * . **. :.: :* : : :*: :* :* * : * *: .* :: : . .:: ::*.* ..* . :::.* ** : *** *: : *:. . . : : :::: : .: *:. * :*.. ** : ...:: . : :. . : ..*. :* * *.. ::* ::.::* * .: . .. * :.** * : .. : : * . .:* * : : ..*. :*.:: ** . * . : : ::.: *:: *: :. *. . * : :*: * : ** . : :* * .::. :. .. *:** :::: :. : .. . ::: : ", "identical_positions": 71, "similar_positions": 163, "identity": "8.32%" }, { "cls_id": "homologset.agr.HGNC:32003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B6VQA5-1", "uniprot_id": "SPT31_RAT", "id": "B6VQA5-1", "name": "Spermatogenesis-associated protein 31", "aln": "MENLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYLLLLPFLESH-------------------------------------------------------------------------------------------------------------------LSSSPS---------DINFTRKPQ--------------------------------------------------------------------------------------IQMTWQSQYMKKFRNHCRNDAKAWEECLKKLK------------------------------------EKEKDELFLEEMSPGHHLNSLGNMFNSASAKQDSTTLSPFWNLKEKSEEQMATQKLSYPKISGDHLQEKYDQLYWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIHLQDKMSPVLPHTHPLSYLDLQPPPLILSPLEFQSP----ALNQVHFQSPLPVLLPSSLPYSRDSGACYSQSQSKPHCPTT-EIQYRERPLVTKQLESRLTLPLMVQK--DAYSILASNPSHDWAVPIFPDNFPISCELRDKLEQHIQKWFIQHQWYFPPEIQESEEVMGLQNSVTGNYQIRDQPCTSQAHMSTGEHNKQGQKVKFQLENESCKNLGPILGKGPKDPVKGLEKNVVKVQGANILEPERNLVKHFKSDSRNDSS-NYIDEDLENNWKANFGTKSGQINQGLTPLSMRQSWLAMNDSFCDTDIHMETRNLTAIKSSEKFMCSREKLAFLNPETRQTLEEHVVRFWVKHRWGLPLKMLKPINLFKLKSTESLPLTLCTQPSSTNSVHRTNSAVEVVRFLGKP---CLRQIIIKDSSPPPGNLLLVSSPSCKRA--AIRRPPSGVDHEPSVALPNKPQSAYLAETLAYNFMETPTQSG---GVLKDEMETEEVL----------------------------------LLPRMTCAPNLRAHNPQAKVVSEYPYNVETELTGQPQIYTTSVLLPK-HSRSMPLPVDTLTSNALG-----------------DIVMVDGGNGLVQQRPSTPKHQVSQKGQIKMLVPTYQGEDTKRQSERKYED------MSKFSPVTERKNNFENQYYQTLPKTTQVLPESLFQRLLSRFLPRVHPKKTIKGQECHPQKDNPTAATAQNQRRQVRKQPYMDDNVTEAQKLMTTVGQMLEKKMM-QHQHHASKVNQPRVVPPGPTSWFSHGHMPVSCLKRRRPPSYPANSL-----CQRRYIQGRHNRGQLPQKSVQFSQKPQILRNPRHMYPKS-----------ALNVVNSSQNRTTVPRTPNQHLCCPRHCAFQRNVCRELGHPSVAFPNRKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAF0-1", "uniprot_id": "SPT31_MOUSE", "id": "E9QAF0-1", "name": "Spermatogenesis-associated protein 31", "aln": "MESLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYHLLLPFLESH-------------------------------------------------------------------------------------------------------------------LSSPPS---------NIKFTRKPQ--------------------------------------------------------------------------------------IQMTWQSQFKKKFRNHCRNDAKAWGECLKKLK------------------------------------EKEKDKLFLEEMSPGHHLNSLGNIFNSSSAKQDSTTLSPFWNLKEKSEEQVATQKLSYPKISEDHFQQKCDQLFWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIQLQDKMSPMLPHTHPLSYLDLQSPHLILSPLEFQTP----ALN-------LPVLLPSSLPYNSDFGTSYSQSQSKPQYLPT-EIKYNKKPSLAKQIENRSTLPLMVQKPQEAYDILAPNPSQDWVVSILPDNFPICRELREKLEQHIQKWLIQHQWNFPHKIQVSEKMKELQNTVIGNCQTRDKPGTLQA---LGEHSNEGQKRKFQLEKESGKNLGPILGKISKDPIRGLEK-------------------------------TTAIKDLENNLKAHLGTKSGQIDQGLTPLSMRQSWLAVDDSFYEMEN-----NLTSLKSSAKSMCSSEKLAFLKPETRQALEAHIVRFWAKHRWSLPLKILKPVKLFQLS-IESLPVVLCAQTSSTTSVHRTRSAAEVVRFLGKP---CLRQMIIEDSSPSPQNLLLVSSPSCKR---ARRRLPFGVDHEPSTALPTKPECGHISEDLTYNFMNTTSQTR---TIFKKEIETREVV----------------------------------LLPRRTSDQNLEAYKHQEKVVSEFPHNVETELAGQPQIYTTTVLPPK-RSRSMPLPVDTLTSHVLG-----------------DIVVADMDNSLVQQRPSTPKHLVSQKSQIKMLAPTYQSEGTKRQSEIKYED------RPKLTPVTEKKANFGSQYYQTLPKIAQVLPGRPPQRHLGRFLQWIHPKKTIKGHEFHPLKGNPTAAIVQNQRRQVRKIPYMDNNVTEAQELMTTVGQMLEKKMMLQHQPYASKFNQHREVPPAPMSRFSHGHMPVSYLQQRRAPSYPGSCS-----CQRCSVQNRHIRNQLPQRSVRFSKKPQNPRNPSHKKPQNPRNPSRLSRNAALNLVNS-QNRTIVPGNSNHHLYCPRHCALQRDVCRELGHSSVVFPNRKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VYP0-1", "uniprot_id": "S31A3_HUMAN", "id": "Q5VYP0-1", "name": "Spermatogenesis-associated protein 31A3", "aln": "MENLPFPLKLLSASSLNAPSSTPWVLDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSPGKRKCPVGRRRRPRGRMKNHSLRAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEPMEDAAPILSLLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVPQSLSPHEDLVASVPAISGLGGSNSHVSASSRWQETARTSCAFNSSVQQDHLSRHPPETCQMEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEKENVGSFTNRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKWIIQHWGNLG-RIQESLDLMQLQDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERDPCPHLGQILGETPQNLSRDMKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPVSNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSEVEVDMFLRKPPMASLRKQVLTKASDHMPESLLASSPAWKQFQRAPRGIPSWNDHEPLKPPPAGQEGRWPSKPLTYSLTGSTQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDVHGFEAPGTSKSSLHPRVSVSQDPRKLCLMEEVVSEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVHEEPRKPNCQGSCKSQRPMFPPIHKSEKFRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKKQPPSVSPFGENIKQIFQWIFSKK----------KSKPAPVTAESQK-TVKNRSCVYSSSAEAQGLMTAVGQMLDEKMSLCHARHASKVNQHKQKFQAPVCGFPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQIRNQQPLKSVRCNNEQWGLRHPQILHPKK-----------AVSPVSPPQHWPKTSGASSHHHHCPRHCLLWEGI----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** *: : :: * : *** *.:*::*::* .**:: ****:*. . *:*.** .:. :: *: ::: .*:: :. *. * ::.. : *.: ***: * :.*:* :***** *: :* .*:**:*. .****: *:*:: ..**** *:: : : :: .**:************* **:.: : ** ** **** :*.* **: : .***:* :::***:*. : :* *. :*:.. * :*** *: . : *.. . **.* : . * :: : * : :*:*.* :** *** :.:.: :.* .:: ..*:*:***:. *** :*****:**:*** : .** * .: **: *. * :.:* . *: ** .::.** *****.:. :** ***: .:: :.::. .:** **::* : ** ::** *: :*:****::::: : **:: **. : : : *:**:* *:* * *:****.****.***::***:: *:*. .**.:. : .**:.. : * .** ** ** .**: :: .:* : **.***: *: * * * **** . * : :: *:*.: :. *: .. **.*.: * ** : : . :****: .: *: ***: :: ** *. :: :* . :.*.*:. . ::. . **::.* .*: * *.* *: * ::.* :: . *:*: .:::** : : .. .: * **. * . . : ::: :..** *.:*:.. .:.*: *:: . : .. :*** ***:*****::** * :***.** : .* . *. .* : :: * **.... .* :.*: *.* * :**: .:: *:* *:. *:. *.. *: . .. ..:* ***** : ..: ", "identical_positions": 320, "similar_positions": 347, "identity": "23.09%" }, { "cls_id": "homologset.agr.HGNC:32005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B6VQA5-1", "uniprot_id": "SPT31_RAT", "id": "B6VQA5-1", "name": "Spermatogenesis-associated protein 31", "aln": "MENLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYLLLLPFLESH-------------------------------------------------------------------------------------------------------------------LSSSPS---------DINFTRKPQ--------------------------------------------------------------------------------------IQMTWQSQYMKKFRNHCRNDAKAWEECLKKLK------------------------------------EKEKDELFLEEMSPGHHLNSLGNMFNSASAKQDSTTLSPFWNLKEKSEEQMATQKLSYPKISGDHLQEKYDQLYWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIHLQDKMSPVLPHTHPLSYLDLQPPPLILSPLEFQSP----ALNQVHFQSPLPVLLPSSLPYSRDSGACYSQSQSKPHCPTT-EIQYRERPLVTKQLESRLTLPLMVQK--DAYSILASNPSHDWAVPIFPDNFPISCELRDKLEQHIQKWFIQHQWYFPPEIQESEEVMGLQNSVTGNYQIRDQPCTSQAHMSTGEHNKQGQKVKFQLENESCKNLGPILGKGPKDPVKGLEKNVVKVQGANILEPERNLVKHFKSDSRNDSS-NYIDEDLENNWKANFGTKSGQINQGLTPLSMRQSWLAMNDSFCDTDIHMETRNLTAIKSSEKFMCSREKLAFLNPETRQTLEEHVVRFWVKHRWGLPLKMLKPINLFKLKSTESLPLTLCTQPSSTNSVHRTNSAVEVVRFLGKP---CLRQIIIKDSSPPPGNLLLVSSPSCKRA--AIRRPPSGVDHEPSVALPNKPQSAYLAETLAYNFMETPTQSG---GVLKDEMETEEVL----------------------------------LLPRMTCAPNLRAHNPQAKVVSEYPYNVETELTGQPQIYTTSVLLPK-HSRSMPLPVDTLTSNALG-----------------DIVMVDGGNGLVQQRPSTPKHQVSQKGQIKMLVPTYQGEDTKRQSERKYED------MSKFSPVTERKNNFENQYYQTLPKTTQVLPESLFQRLLSRFLPRVHPKKTIKGQECHPQKDNPTAATAQNQRRQVRKQPYMDDNVTEAQKLMTTVGQMLEKKMM-QHQHHASKVNQPRVVPPGPTSWFSHGHMPVSCLKRRRPPSYPANSL-----CQRRYIQGRHNRGQLPQKSVQFSQKPQILRNPRHMYPKS-----------ALNVVNSSQNRTTVPRTPNQHLCCPRHCAFQRNVCRELGHPSVAFPNRKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAF0-1", "uniprot_id": "SPT31_MOUSE", "id": "E9QAF0-1", "name": "Spermatogenesis-associated protein 31", "aln": "MESLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYHLLLPFLESH-------------------------------------------------------------------------------------------------------------------LSSPPS---------NIKFTRKPQ--------------------------------------------------------------------------------------IQMTWQSQFKKKFRNHCRNDAKAWGECLKKLK------------------------------------EKEKDKLFLEEMSPGHHLNSLGNIFNSSSAKQDSTTLSPFWNLKEKSEEQVATQKLSYPKISEDHFQQKCDQLFWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIQLQDKMSPMLPHTHPLSYLDLQSPHLILSPLEFQTP----ALN-------LPVLLPSSLPYNSDFGTSYSQSQSKPQYLPT-EIKYNKKPSLAKQIENRSTLPLMVQKPQEAYDILAPNPSQDWVVSILPDNFPICRELREKLEQHIQKWLIQHQWNFPHKIQVSEKMKELQNTVIGNCQTRDKPGTLQA---LGEHSNEGQKRKFQLEKESGKNLGPILGKISKDPIRGLEK-------------------------------TTAIKDLENNLKAHLGTKSGQIDQGLTPLSMRQSWLAVDDSFYEMEN-----NLTSLKSSAKSMCSSEKLAFLKPETRQALEAHIVRFWAKHRWSLPLKILKPVKLFQLS-IESLPVVLCAQTSSTTSVHRTRSAAEVVRFLGKP---CLRQMIIEDSSPSPQNLLLVSSPSCKR---ARRRLPFGVDHEPSTALPTKPECGHISEDLTYNFMNTTSQTR---TIFKKEIETREVV----------------------------------LLPRRTSDQNLEAYKHQEKVVSEFPHNVETELAGQPQIYTTTVLPPK-RSRSMPLPVDTLTSHVLG-----------------DIVVADMDNSLVQQRPSTPKHLVSQKSQIKMLAPTYQSEGTKRQSEIKYED------RPKLTPVTEKKANFGSQYYQTLPKIAQVLPGRPPQRHLGRFLQWIHPKKTIKGHEFHPLKGNPTAAIVQNQRRQVRKIPYMDNNVTEAQELMTTVGQMLEKKMMLQHQPYASKFNQHREVPPAPMSRFSHGHMPVSYLQQRRAPSYPGSCS-----CQRCSVQNRHIRNQLPQRSVRFSKKPQNPRNPSHKKPQNPRNPSRLSRNAALNLVNS-QNRTIVPGNSNHHLYCPRHCALQRDVCRELGHSSVVFPNRKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VU36-1", "uniprot_id": "S31A5_HUMAN", "id": "Q5VU36-1", "name": "Spermatogenesis-associated protein 31A5", "aln": "MENLPFPLKLLSASSLNAPSSTPWVLDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSPGKRKCPVGRRRRPRGRMKNHSLRAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEPMEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVPQSLSPHEDLVASVPAISGLGGSNSHVSASSRWQETARTSCAFNSSVQQDHLSRHPPETCQMEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEKENVGSFTNRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKWIIQHWGNLG-RIQESLDLMQLRDESPGTSQAKGKPSPWQSSMSTGEGSKEAQKVKFQLERDPCPHLGQILGETPQNLSRDMKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVCVRRSWLAVNQALPVSNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSEVEVDMFLRKPPMASLRKQVLTKASDHMPESLLASSPAWKQFQRAPRGIPSWNDHEPLKPPPAGQEGRWPSKPLTYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDVHGFEAPGTSKSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVHEEPRNPNCQGSCKSQRPMFPPIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKKQPPSVSPFGENIKQIFQWIFSKK----------KSKPAPVTAESQK-TVKNRSRVYSSSAEAQGLMTAVGQMLDEKMSLCHARHASKVNQHKQKFQAPVCGFPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQIRNQQPLKSVRCNNEQWGLRHPQILHPKK-----------AVSPVSPPQHWPKTSGASSHHHHCPRHCLLWEGI----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** *: : :: * : *** *.:*::*::* .**:: ****:*. . *:*.** .:. :: *: ::: .*:: :. *. * ::.. : *.: ***: * :.*:* :***** *: :* .*:**:*. .****: *:*:: ..**** *:: : : :: .**:************* **:.: : ** ** **** :*.* **: : .***:* :::***:*. : :* *. :*:.. * :*** *: . : *.. . **.* : . * :: : * : :*:*.* :** *** :.:.: :.* .:: ..*:*:***:. *** :*****:**:*** : .** * .: *:: *. * :.:* . *: ** .::.** *****.:. :** ***: .:: :.::. .:** **::* : ** ::** *:.:*:****::::: : **:: **. : : : *:**:* *:* * *:****.****.***::***:: *:*. .**.:. : .**:.. : * .** ** ** .**: :: .:* : **.***: *: * * * **** . * : :: *:*.: : *: .. **.*.: * ** : : . :**.*: .: *: ***: :: ** *. :: :* . :.*.*:. . ::. . **::.* .*: * *.* *: * ::.* ::: . *:*: .:::** : : .. .: * **. * . . : ::: :..** *.:*:.. .:.*: *:: . : .. :*** ***:*****::** * :***.** : .* . *. .* : :: * **.... .* :.*: *.* * :**: .:: *:* *:. *:. *.. *: . .. ..:* ***** : ..: ", "identical_positions": 318, "similar_positions": 350, "identity": "22.94%" }, { "cls_id": "homologset.agr.HGNC:32006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B6VQA5-1", "uniprot_id": "SPT31_RAT", "id": "B6VQA5-1", "name": "Spermatogenesis-associated protein 31", "aln": "MENLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYLLLLPFLESHLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------SSPSDINFTRKPQ---------------------------------------------IQMTWQSQYMKKFRNHCRNDAKAWEECLKKLK------------------------------------EKEKDELFLEEMSPGHHLNSLGNMFNSASAKQDSTTLSPFWNLKEKSEEQMATQKLSYPKISGDHLQEKYDQLYWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIHLQDKMSPVLPHTHPLSYLD--LQPPPLILSPLEFQSPALNQVHFQSPLPVLLPSSLPYSRDSGACYSQSQSKPHCPTT-EIQYRERPLVTKQLESRLTLPLMVQK--DAYSILASNPSHDWAVPIFPDNFPISCELRDKLEQHIQKWFIQHQWYFPPEIQESEEVMGLQNSVTGNYQIRDQPCTSQAHMSTGEHNKQGQKVKFQLENESCKNLGPILGKGPKDPVKGLEKNVVKVQGANILEPERNLVKHFKSDSRNDSS-NYIDEDLENNWKANFGTKSGQINQGLTPLSMRQSWLAMNDSFCDTDIHMETRNLTAIKSSEKFMCSREKLAFLNPETRQTLEEHVVRFWVKHRWGLPLKMLKPINLFKLKSTESLPLTLCTQPSSTNSVHRTNSAVEVVRFLGKP---CLRQIIIKDSSPPPGNLLLVSSPSCKRA--AIRRPPSGVDHEPSVALPNKPQSAYLAETLAYNFMETPTQSG---GVLKDEMETEEVL----------------------------------LLPRMTCAPNLRAHNPQAKVVSEYPYNVETELTGQPQIYTTSVLLPK-HSRSMPLPVDTLTSNALG-----------------DIVMVDGGNGLVQQRPSTPKHQVSQKGQIKMLVPTYQGEDTKRQSERKYED------MSKFSPVTERKNNFENQYYQTLPKTTQVLPESLFQRLLSRFLPRVHPKKTIKGQECHPQKDNPTAATAQNQRRQVRKQPYMDDNVTEAQKLMTTVGQMLEKKMM-QHQHHASKVNQPRVVPPGPTSWFSHGHMPVSCLKRRRPPSYPANSL-----CQRRYIQGRHNRGQLPQKSVQFSQKPQILRNPRHMYPKS-----------ALNVVNSSQNRTTVPRTPNQHLCCPRHCAFQRNVCRELGHPSVAFPNRKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAF0-1", "uniprot_id": "SPT31_MOUSE", "id": "E9QAF0-1", "name": "Spermatogenesis-associated protein 31", "aln": "MESLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYHLLLPFLESHLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------SPPSNIKFTRKPQ---------------------------------------------IQMTWQSQFKKKFRNHCRNDAKAWGECLKKLK------------------------------------EKEKDKLFLEEMSPGHHLNSLGNIFNSSSAKQDSTTLSPFWNLKEKSEEQVATQKLSYPKISEDHFQQKCDQLFWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIQLQDKMSPMLPHTHPLSYLD--LQSPHLILSPLEFQTPALN-------LPVLLPSSLPYNSDFGTSYSQSQSKPQYLPT-EIKYNKKPSLAKQIENRSTLPLMVQKPQEAYDILAPNPSQDWVVSILPDNFPICRELREKLEQHIQKWLIQHQWNFPHKIQVSEKMKELQNTVIGNCQTRDKPGTLQA---LGEHSNEGQKRKFQLEKESGKNLGPILGKISKDPIRGLEK-------------------------------TTAIKDLENNLKAHLGTKSGQIDQGLTPLSMRQSWLAVDDSFYEMEN-----NLTSLKSSAKSMCSSEKLAFLKPETRQALEAHIVRFWAKHRWSLPLKILKPVKLFQLS-IESLPVVLCAQTSSTTSVHRTRSAAEVVRFLGKP---CLRQMIIEDSSPSPQNLLLVSSPSCKR---ARRRLPFGVDHEPSTALPTKPECGHISEDLTYNFMNTTSQTR---TIFKKEIETREVV----------------------------------LLPRRTSDQNLEAYKHQEKVVSEFPHNVETELAGQPQIYTTTVLPPK-RSRSMPLPVDTLTSHVLG-----------------DIVVADMDNSLVQQRPSTPKHLVSQKSQIKMLAPTYQSEGTKRQSEIKYED------RPKLTPVTEKKANFGSQYYQTLPKIAQVLPGRPPQRHLGRFLQWIHPKKTIKGHEFHPLKGNPTAAIVQNQRRQVRKIPYMDNNVTEAQELMTTVGQMLEKKMMLQHQPYASKFNQHREVPPAPMSRFSHGHMPVSYLQQRRAPSYPGSCS-----CQRCSVQNRHIRNQLPQRSVRFSKKPQNPRNPSHKKPQNPRNPSRLSRNAALNLVNS-QNRTIVPGNSNHHLYCPRHCALQRDVCRELGHSSVVFPNRKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VVP1-1", "uniprot_id": "S31A6_HUMAN", "id": "Q5VVP1-1", "name": "Spermatogenesis-associated protein 31A6", "aln": "MENLPFPLKLLSASSLNAPSSTPWVLDIFLTLVFALGFFFLLLPYLSYFHCDDPPSPSPGKRKCPVGRRRRPRGRMKNHSLRAGRECPRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEPMEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHTPDPLACSPPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVPQSLSPHEDLVASVPAISGLGGSNSHVSASSRWQETARTSCAFNSSVQQDPLSRHPPETCQMEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEKENVGSFTNQMTPEKHLNSLGNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKCSDPRLLQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHRQPFISSTPQFLPTPMAQAEAQA--HLQSSFPVLSPAFPSLIKNTGVACPASQNKVQALSLPETQHPEWPLLRKQLEGRLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKWIIQHWGNLG-RIQESLDLMQLRDESPGTSQAKGKPSPWQSSTSTGESSKEAQKVKFQLERDLCPHLGQILGETPQNLSRDMKSFPRKVLGVTSEESERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPVSNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSEVEVDMFLRKPPMASLRKQVLTKASDHMPESLLASSPAWKQFQRAPRGIPSWNDHGPLKPPPAGQEGRWPSKPLTYSLTGSTQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDVHGFEAPGTSKSSLHPRVSVSQDPRKLCLMEEVVSEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVQEEPRNPNCQGSCKSQRPMFPPIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKKQPPSVSHFGENIKQFFQWIFSKK----------KSKPAPVTAESQK-TVKNRSCVYSSSAEAQGLMTAVGQMLDKKMSLCHAHHASKVNQHKQKFQAPVCGFPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQIRNQQPLKSVRCNNEQWGLRHPQILHPKK-----------AVSPVSPPQHWPKTSGASSHHHHCPRHCLLWEGI----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** *: : :: * : *** *.:*::*::* .**:: ****:*. . . *.*. ** * ::: .*:: :. *. * ::.. : *.: ***: * ::*:* :*******: :* .*:**:*. .****: *:*:: ..** * *:: : : :: .**:************* **:.: : ** ** **** :*.* **: : .***:* :::***: : :... :*.. *: * :*** *: . : *.. . **.* : . * :: : * : **:*.* :** *** :.:.: :.* .:: ..*:*:***:. *** :*****:**:*** : .** * .: *:: *. * :.:* . *: ** .::.** *****.: :** ***: .:: :.::. .:** **::* : ** ::** *: :*:****::::: : **:: **. : : : *:**:* *:* * *:****.****.***::***:: *:*. .**.:. : .**:.. : * .** ** ** .**: :: .:* : **.***: *: * * * ** * . * : :: *:*.: :. *: .. **.*.: * ** : : . :****: .: *: ***: :: ** *. :: :* . :.*.*:. . ::. . ***:.* .*: * *.* *: * ::.* ::: . *:*: .:::** : : .. .: * **. * . . : :*: :..** *.:*:.. .:.*: *:: . : .. :*** ***:*****:*** * :***.** : .* . *. .* : :: * **.... .* :.*: *.* * :**: .:: *:* *:. *:. *.. *: . .. ..:* ***** : ..: ", "identical_positions": 320, "similar_positions": 340, "identity": "23.12%" }, { "cls_id": "homologset.agr.HGNC:32007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B6VQA5-1", "uniprot_id": "SPT31_RAT", "id": "B6VQA5-1", "name": "Spermatogenesis-associated protein 31", "aln": "MENLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYLLLLPFLESH-------------------------------------------------------------------------------------------------------------------LSSSPS---------DINFTRKPQ--------------------------------------------------------------------------------------IQMTWQSQYMKKFRNHCRNDAKAWEECLKKLK------------------------------------EKEKDELFLEEMSPGHHLNSLGNMFNSASAKQDSTTLSPFWNLKEKSEEQMATQKLSYPKISGDHLQEKYDQLYWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIHLQDKMSPVLPHTHPLSYLDLQPPPLILSPLEFQSP----ALNQVHFQSPLPVLLPSSLPYSRDSGACYSQSQSKPHCPTT-EIQYRERPLVTKQLESRLTLPLMVQK--DAYSILASNPSHDWAVPIFPDNFPISCELRDKLEQHIQKWFIQHQWYFPPEIQESEEVMGLQNSVTGNYQIRDQPCTSQAHMSTGEHNKQGQKVKFQLENESCKNLGPILGKGPKDPVKGLEKNVVKVQGANILEPERNLVKHFKSDSRNDSS-NYIDEDLENNWKANFGTKSGQINQGLTPLSMRQSWLAMNDSFCDTDIHMETRNLTAIKSSEKFMCSREKLAFLNPETRQTLEEHVVRFWVKHRWGLPLKMLKPINLFKLKSTESLPLTLCTQPSSTNSVHRTNSAVEVVRFLGKP---CLRQIIIKDSSPPPGNLLLVSSPSCKRA--AIRRPPSGVDHEPSVALPNKPQSAYLAETLAYNFMETPTQSG---GVLKDEMETEEVL----------------------------------LLPRMTCAPNLRAHNPQAKVVSEYPYNVETELTGQPQIYTTSVLLPK-HSRSMPLPVDTLTSNALG-----------------DIVMVDGGNGLVQQRPSTPKHQVSQKGQIKMLVPTYQGEDTKRQSERKYED------MSKFSPVTERKNNFENQYYQTLPKTTQVLPESLFQRLLSRFLPRVHPKKTIKGQECHPQKDNPTAATAQNQRRQVRKQPYMDDNVTEAQKLMTTVGQMLEKKMM-QHQHHASKVNQPRVVPPGPTSWFSHGHMPVSCLKRRRPPSYPANSL-----CQRRYIQGRHNRGQLPQKSVQFSQKPQILRNPRHMYPKS-----------ALNVVNSSQNRTTVPRTPNQHLCCPRHCAFQRNVCRELGHPSVAFPNRKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAF0-1", "uniprot_id": "SPT31_MOUSE", "id": "E9QAF0-1", "name": "Spermatogenesis-associated protein 31", "aln": "MESLPSLLESIYTTWL-SLSSTIWAMDMILAFVCGLGLYHLLLPFLESH-------------------------------------------------------------------------------------------------------------------LSSPPS---------NIKFTRKPQ--------------------------------------------------------------------------------------IQMTWQSQFKKKFRNHCRNDAKAWGECLKKLK------------------------------------EKEKDKLFLEEMSPGHHLNSLGNIFNSSSAKQDSTTLSPFWNLKEKSEEQVATQKLSYPKISEDHFQQKCDQLFWGLPSLHSESLVAAAWIPQTTSTLPSPFFLFNVISSVYPIQLQDKMSPMLPHTHPLSYLDLQSPHLILSPLEFQTP----ALN-------LPVLLPSSLPYNSDFGTSYSQSQSKPQYLPT-EIKYNKKPSLAKQIENRSTLPLMVQKPQEAYDILAPNPSQDWVVSILPDNFPICRELREKLEQHIQKWLIQHQWNFPHKIQVSEKMKELQNTVIGNCQTRDKPGTLQA---LGEHSNEGQKRKFQLEKESGKNLGPILGKISKDPIRGLEK-------------------------------TTAIKDLENNLKAHLGTKSGQIDQGLTPLSMRQSWLAVDDSFYEMEN-----NLTSLKSSAKSMCSSEKLAFLKPETRQALEAHIVRFWAKHRWSLPLKILKPVKLFQLS-IESLPVVLCAQTSSTTSVHRTRSAAEVVRFLGKP---CLRQMIIEDSSPSPQNLLLVSSPSCKR---ARRRLPFGVDHEPSTALPTKPECGHISEDLTYNFMNTTSQTR---TIFKKEIETREVV----------------------------------LLPRRTSDQNLEAYKHQEKVVSEFPHNVETELAGQPQIYTTTVLPPK-RSRSMPLPVDTLTSHVLG-----------------DIVVADMDNSLVQQRPSTPKHLVSQKSQIKMLAPTYQSEGTKRQSEIKYED------RPKLTPVTEKKANFGSQYYQTLPKIAQVLPGRPPQRHLGRFLQWIHPKKTIKGHEFHPLKGNPTAAIVQNQRRQVRKIPYMDNNVTEAQELMTTVGQMLEKKMMLQHQPYASKFNQHREVPPAPMSRFSHGHMPVSYLQQRRAPSYPGSCS-----CQRCSVQNRHIRNQLPQRSVRFSKKPQNPRNPSHKKPQNPRNPSRLSRNAALNLVNS-QNRTIVPGNSNHHLYCPRHCALQRDVCRELGHSSVVFPNRKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWB4-1", "uniprot_id": "S31A7_HUMAN", "id": "Q8IWB4-1", "name": "Spermatogenesis-associated protein 31A7", "aln": "MENLPFPLKLLSASSLNAPSSTPWVLDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSPGKRKCPVGRRRRPRGRMKNHSLRAGRECPRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEPMEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVPQSLSPHEDLVASVPAISGLGGSNSHVSASSRWQETARTSCAFNSSVQQDHLSRHPPETCQMEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEKENVGSFTNRMTPEKHLNYLRNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKWIIQHWGNLG-RIQESLDLMQLRDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERDPCPHLGQILGETPQNLSRDMKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVCVRRSWLAVNQALPVSNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSEVEVDMFLRKPPMASLRKQVLTKASDHMPESLLASSPAWKQFQRAPRGIPSWNDHEPLKPPPAGQEGRWPSKPLTYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDVHGFEAPGTSKSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVHEEPRNPNCQGSCKSQRPMFPPIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKKQPPSVSPFGENIKQIFQWIFSKK----------KSKPAPVTAESQK-TVKNRSRVYSSSAEAQGLMTAVGQMLDEKMSLCHARHASKVNQHKQKFQAPVCGFPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQIRNQQPLKSVRCNNEQWGLRHPQILHPKK-----------AVSPVSPPQHWPKTSGASSHHHHCPRHCLLWEGI----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** *: : :: * : *** *.:*::*::* .**:: ****:*. . *:*.** .:. :: *: ::: .*:: :. *. * ::.. : *.: ***: * :.*:* :*** * *: :* .*:**:*. .****: *:*:: ..**** *:: : : :: .**:************* **:.: : ** ** **** :*.* **: : .***:* :::***:*. : :* *. :*:.. * :*** *: . : *.. . **.* : . * :: : * : :*:*.* :** *** :.:.: :.* .:: ..*:*:***:. *** :*****:**:*** : .** * .: *:: *. * :.:* . *: ** .::.** *****.:. :** ***: .:: :.::. .:** **::* : ** ::** *:.:*:****::::: : **:: **. : : : *:**:* *:* * *:****.****.***::***:: *:*. .**.:. : .**:.. : * .** ** ** .**: :: .:* : **.***: *: * * * **** . * : :: *:*.: : *: .. **.*.: * ** : : . :**.*: .: *: ***: :: ** *. :: :* . :.*.*:. . ::. . **::.* .*: * *.* *: * ::.* ::: . *:*: .:::** : : .. .: * **. * . . : ::: :..** *.:*:.. .:.*: *:: . : .. :*** ***:*****::** * :***.** : .* . *. .* : :: * **.... .* :.*: *.* * :**: .:: *:* *:. *:. *.. *: . .. ..:* ***** : ..: ", "identical_positions": 317, "similar_positions": 350, "identity": "22.87%" }, { "cls_id": "homologset.agr.HGNC:32008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R6Y6-1", "uniprot_id": "M0R6Y6_RAT", "id": "M0R6Y6-1", "name": "", "aln": "MSGQLERCEREWHELEGEFQELQETHRIYKQKLEELTALQTQCSISISKQKRHLKDLKYALQRYKCHSSQEEAELVQQLAANIKERQNVFFDMEAYLPKKNGLYLNLVLGNVDVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAVACRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSSFLSGVMLTWPNGLIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLFCGHFWQLYNAVTLFELSSHEECKEWQVFVLALTFLILFLGNFLTTLKVVHAKL----------------QKNRNKTKQP-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TA38-1", "uniprot_id": "T120B_MOUSE", "id": "Q3TA38-1", "name": "Transmembrane protein 120B", "aln": "MSGQLERCEREWHELEGEFQELQETHRIYKQKLEELTSLQTLCSTSISKQKRHLKDLKHTLQRYKRHSSHEEAALIQQMTANIKERQNVFFDMEAYLPKKNGLYLNLVLGNVSVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAVACRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPNGLIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLFCGHFWQLYNAVTLFELSTHEECKEWQVFVLALTFLILFLGNFLTTLKVVHAKL----------------HKNRNKTKQP-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PK00-1", "uniprot_id": "T120B_HUMAN", "id": "A0PK00-1", "name": "Transmembrane protein 120B", "aln": "MSGQLERCEREWHELEGEFQELQETHRIYKQKLEELAALQTLCSSSISKQKKHLKDLKLTLQRCKRHASREEAELVQQMAANIKERQDVFFDMEAYLPKKNGLYLNLVLGNVNVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAVACRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPNGPIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLFCGHFWQLYNAVTLFELSSHEECREWQVFVLAFTFLILFLGNFLTTLKVVHAKL----------------QKNRGKTKQP-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY80-1", "uniprot_id": "T120B_DANRE", "id": "Q1LY80-1", "name": "Transmembrane protein 120B", "aln": "MS--LERCQSEWTEIEQEYQQLQETHKVYRQKLEELTNLQAICSSAISKQRKGLKDLKQSLYKCKKSCNGKDSEVINDLQVQIKERQNVFFDMEAYLPKRNGLYLNLVLGNVNVTLLSNQAKFAYKDEYEKFKLYMTIILMFGAVTCLFLLNYRVTDEIFNFLLVWYYCTLTIRESILRSNGSRIKGWWVSHHYVSTFLSGVMLTWPEGPMYQMFRSQFLAFSIYQSCVQFLQYYYQSGCLYRLRALGERNQLDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLYNAVTLFRLSALDDCKEWQVFMLALTFLVLFLGNFLTTLKVVHQKL----------------LKNKDKVKNN-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1M2-1", "uniprot_id": "TM120_DROME", "id": "Q9U1M2-1", "name": "Transmembrane protein 120 homolog", "aln": "MN--IDSLKNEWEELNKEFAELESCNRRYIELLEQLHSHQQICFNEIKHQRYRMNQITTSLRQFKGPVPAEDKEKVDDLHKMTLKRKAQLHEIEQSLPAKSGRYLQIILGDVNVSILNRNDKVRYKDDYEKFKLILNVIGLIMAFFN-LIFNYRALELAFIFLLVWYYCTLTIRESILKVNGSRIKGWWRAHHFISTVAAGVLLVWPQGEHWQIFRMQFMYFNVYISIVQYLQFGYQKGLLYRLKALGERHNMDITIEGFHSWMWRGLSFLLPFLFIGYGYQAYNAWTLYKLAYSPPDAPWHVSVMSGLFLLLFVGNMATTLWVVPEKIRERAKERYRLQSMGKSMKLRKEMKNSASDLDLSSGSKLSPTATTTTSIATATQTPAEKKET", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: : ** *:: *: :*:. :: * : **:* * * *.:*: ::::. :* : * :: :::: :*: :.::* ** :.* **:::**:*.*::*..: *. ***:****** :.:* :: *. ::::**. : * ***************** ********* :**::*:. :**:*.**:* :* ** **: *.:: * **:**: ** * ****:*****:::*:*:***:*******:******* *: :* *** **:.*: *:* ::: **:**:**: *** ** *: * : : *: ", "identical_positions": 144, "similar_positions": 102, "identity": "36.92%" }, { "cls_id": "homologset.agr.HGNC:32016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TN78-1", "uniprot_id": "ACSM4_RAT", "id": "Q7TN78-1", "name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "aln": "MKVLLRCQRLRFIWLAKPAGRHFHRDPQLWAPLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEHNCVQTGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFNTDTFLDTLTSYPITTLCSAPTVYRMLVQQDLKRYQFKRLRHCLTGGEPLNPEVLEQWKAQTGLELYEGYGQTEVGIICANRKGEEIKPGSMGKGVVPYDVQIIDEHGNILPSGKEGEIALRLGSDRPFCFFSEYVDNPEKTDATIRRNFYITGDRGVMDDDGYLWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W40-1", "uniprot_id": "ACSM4_MOUSE", "id": "Q80W40-1", "name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "aln": "MKVLLHCQRLRFIWLAKPAGRHFHRDSQLWAPLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIVSECPSLKTKLLVSPHHWDGWLNFQELLQSASEEHNCVETGSQEPMAIYFTSGTTGSPKMAQHSQGSLGIGYTLCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFDTDIFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYQFKRLRHCLTGGEPLNPEVLEQWKMQTGLELYEGYGQTEVGIICANRKGEAIKPGSMGKGVVPYDVQIIDENGNILPSGKEGEIALRLKSDRPFCFFSEYVDNPEKTDATIRRNFYVTGDRGVMDDDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPYKCSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7M7-1", "uniprot_id": "ACSM4_HUMAN", "id": "P0C7M7-1", "name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "aln": "MKIFFRYQTFRFIWLTKPPGRRLHKDHQLWTPLTLADFEAINRCNRPLPKNFNFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWRGR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:::: * :*****:**.**::*:* ***:**** ********::***************** ***:***********************:************************:************:****:***::********* *******:*****************:**. ***.*********: *:***.****:* *****.**:*******:********* ********.*****::*********.****:********:*********:** ************:** ******:********.*********:*****:** *******************: ****************:****:**: *********::*********:**:**.********** . *******:*****:** **** :**:********.***:****************************************** *********:*****:*. * **** *******:*********************************** ", "identical_positions": 491, "similar_positions": 63, "identity": "84.66%" }, { "cls_id": "homologset.agr.HGNC:32017", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70490-1", "uniprot_id": "ACSM2_RAT", "id": "O70490-1", "name": "Acyl-coenzyme A synthetase ACSM2, mitochondrial", "aln": "MHWLWKIPRLCTFWGTEMFHRTFHMNIKKLMPIQWGHQEVPAKFNFASDVIDHWASLEKAGKRSPGPALWWMNGSGEELKWNFRELSEISKQTANVLTGACGLQRGDRVAVVLPRVPEWWLVTLGCMRSGLVFMPGTTQMKSTDILYRLQSSKARAIVAGDEVVQEVDAVAPDCSFLKIKLLVSEKNREGWLNFKALLKDASPIHQCVETVSQESAAIYFTSGTSGPPKMAEHSHCSLGLKAKMDAG-WTGLGPSDTMWTISDTGWILNILGSFLEPWVLGTCIFVHLLPKFDPQTVLKVLSSYPINTLLGAPLIYRMLLQQDLSSYKFPHLHSCFSGGETLLPETLESWKAKTGLEIREIYGQTETGITCRVSRTMKVKPGYLGTAIVPYDVQVIDEQGNVLPPGKEGDMALRVKPIRPIGMFSGYVDNPKKTQANIRGDFWLLGDRGIKDTEGYFHFMGRTDDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRREVVKAFVVLAPEFLSHDQDQLTKVLQEHVKSVTAPYKYPRKVEFVLDLPKTITGKIERAKLRAKEWKTSG-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0L3-1", "uniprot_id": "ACSM2_MOUSE", "id": "Q8K0L3-1", "name": "Acyl-coenzyme A synthetase ACSM2, mitochondrial", "aln": "MHHLWKIPRLFTLWGNEISCRTFHMNIKKLIPIQWGHQEAPAKFNFASDVIDHWASVEKAGKRSSGPALWWMNGSGKEIKWSFRELSEASKQTANVLSGACGLHRGDRVAVVLPRIPEWWLMILGCMRTGLVFMPGTIQMRSSDILYRLQASKARAIVAGDEVAQEVDAVAPDCSFLKIKLLVSENSREGWLNFKALLKEASTIHQCVETESRESAAIYFTSGTSGPPKMAEHSHCSLGIKAKMDAASWTGLSTSDIIWTISDTAWIMNILGAFLEPWVLGACIFVHLLPKFDSQTVLKVLSSYPINTLVGAPIIYRMLLQQDLSSYKFPHLHSCFSGGETLLPETLENWKAKTGLEIREIYGQTETGLICRVSRTMKVKPGYLGTAFAHYDVQVIDEQGNVLPPGKEGDIAIRVKPIWPIGMFSGYVDNPKKTQDNIRGDFWLMGDRGIKDPEGYFHFIGRSDDIINSSGYRIGPSEVENALMEHPAVSETAVISSPDPSRGEVVKAFVVLAPEFLSHDRDQLTKVLQEHVKSVTAPYKYPRKVEFVLDLPKTVTGKIERAKLRAKEWKTSGRA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08AH3-1", "uniprot_id": "ACS2A_HUMAN", "id": "Q08AH3-1", "name": "Acyl-coenzyme A synthetase ACSM2A, mitochondrial", "aln": "MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRANDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *: * *:**.:: **:::* ::*:.:******.**********:****.:****** ..*****:**.*:*: *.****** *:*:****:*****:***********:*****: ***:*:**:***** **:*:******* ***:******** ****:**.:*. *:*******:. :****** **::**. *:**** *:*::********** *******:.***:******. **** .** :******.**:*** :::***.**:* *********. .:**.******::::***::*****************:.*.: **:*******.*:*:***:*** *******: * **:***:****:*** ****:**::*******.***:.:***** ***:********.** ********:******* :***:*:**::************************* ********** * **********.:***** :**** **:**************:****:****:****:***** **** ** ", "identical_positions": 418, "similar_positions": 110, "identity": "72.32%" }, { "cls_id": "homologset.agr.HGNC:32033", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32TKY4-1", "uniprot_id": "A0AB32TKY4_DANRE", "id": "A0AB32TKY4-1", "name": "", "aln": "-----------------------------------------------MAFIKEES--------------------------EDVKIEETFS--------------------------------------------------------------------VKNE----------------------------------DLQEQTDLVKEYERSKEEEHHVKIEDK--------------------------------------THLETDDILKMRDK---------------------------------------------------------------------------------------------------------------RCFTCNQCGKSLANKSKLKIHMRIHNREKLFTCTQCGKNFNQSSNLNQHMRIHTGEKPFTCTQCGKSFSQSSNLNLHMRIHTGEKPFTCSQCGKSFSQSSSLNLHMRIHTGEKPFTCTQCGKSFSQSSILNIHMRNHTGEKPFTCLQCGKSFSQSTYLNQHMRIHTGENLFTCTQCGKSFSNSANLNLHMRIHTGEKPFTCTQCGKSFSQSSNLNIHMRIHTGEKPFTCSQCGKSFSQSPYLNHHMRIHTGEKPFTCSQCGKSFSKSSNLNIHMRIHTGEKPFTCTQCGTSFSQSSNLNIHMRNHTGEKPFTCLQCGKSFSRSTSLNRHMMIHTGEKAFMCLKCENTFITAAELKRHQRVHTGEKPYKCSQCSKRFARSGTLKTHERIHTGEKL--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V348-1", "uniprot_id": "Z658B_HUMAN", "id": "Q4V348-1", "name": "Zinc finger protein 658B", "aln": "MMNLEKNFDKTTLFNHMRTDKRGKCSDLNEYGTSCDKTTAVEYNKVHMAMTHYECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEHNECTDALYQKLDFTAHQRIHTDFTAHQKFYLSDEHGKCRKSFYWKAHLIQHERPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTREKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYKCNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNECGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRIHTGEKPYECDECGKTFVRKAALRVHHTRMHTREKTLACNGFGKS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: : *. *. * **.** :::* .* * .: * : :..: .:*::*. * :**: .: : * :* : : **:**:*:*: * ** * ***.*** : *.:**:.*. .* *. * *****.**: *::* *:*::.* *::* ********:.*.:* *:*::.*:*. * .****** : *::***:* *.: *. * * ******: * :***:***.:**. * ******: : *. ***:* .* * :* ********: *.:***:*** ::* * ********: *.:***:*::.. *. * ********: *.:***:***:*:*. *:* ::****: *::**.:**:.* :. * * ******: * ***.*::.::*. * ******:: * .* :** :.*. ***:*******:*.:*.* **:..**:.*:******* ", "identical_positions": 229, "similar_positions": 142, "identity": "27.96%" }, { "cls_id": "homologset.agr.HGNC:32034", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA20-1", "uniprot_id": "D4AA20_RAT", "id": "D4AA20-1", "name": "Zinc finger protein 697", "aln": "MSFVQPHRKPQREGSGQPARVPARGPIAAASGRRAGARLGQCAQESPGASQGPCFPPCSLSCWMEQEDNLGVCADQSSEDRGMGSDFENSEDQEGDPEERGVGSNPQDTEER-GHLEQELDSNPQDDDLRGDPPERDIVSTVCSEGLLSEEEGAILREEEDDQPGVADMALFPGLSESDSITRSPQGEEEEEEE-EEEESAGENRLIEKEEPLPTPVLPWRRHLSLGGRHRGDKPAYRRFHRLHHPMAVDLGELDSLMASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAMASLEPFGLAGECGGVVGMMG----VGMGVSGGFGAGPTLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAAGGAGSAAAAAAALRPFACGECGKGFVRRSHLANHQRIHTGEKP---HGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKRTHSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFSCGQCEKRFSDFSTLTQHQRTHTGEKPYTCLECGKSFIQSSHLIRHRRIHTGNKPHKCTGCGKGFRYKTHLAQHQKLHLC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q569E7-1", "uniprot_id": "ZN697_MOUSE", "id": "Q569E7-1", "name": "Zinc finger protein 697", "aln": "---------------------------------------------------------------MEQEDNQGVCEYQTSEDRGMDSDLENSEDREGDPEERGMGSNPWDTEDR-GHLEQEVDSNPQDDDLRGDSRERDRASTVCSEGRLSEEERAILREEEDDQPGVADMALFPGLSESDSISRSPRGEEDEEEEDEEEESAGENRLIEEEDPLPTPVLPWRRHLSLGGRHRGDKPAHRRFHRLHHPMAMDLGELDSLMASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAVASLEPFGLAGECGGVVGMMGMGMGVGMGVAGGFGAGPTLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAAGGGAGSAGSAAALRPFACGECGKGFVRRSHLANHQRIHTGEKP---HGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKRTHSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFGCGQCEKRFSDFSTLTQHQRTHTGEKPYTCLECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TEC3-1", "uniprot_id": "ZN697_HUMAN", "id": "Q5TEC3-1", "name": "Zinc finger protein 697", "aln": "---------------------------------------------------------------MKQEDNQGVCAHQDSEDKGMGSDFEDSEDREGDPEEREMGSNPHDTNKREGHPEPEMGSNPQD------SRHREAVPDICTEGQLSEEEGVSVRGEEDDQSGVADMAMFPGLSESDSISRSLREDDD--------ESAGENRLEEEEEQPAPPVLPWRRHLSLGSRHRGDKPAHRRFHRLHHPMAVDLGELDSLVASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAAASLEPFGLAGECDAMVGMMG------VGVAGGFGAGPPLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAASGAG-----AAALRPFACGECGKGFVRRSHLANHQRIHTGEKP---HGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKRTHSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFRCGQCEKRFSDFSTLTQHQRTHTGEKPYTCIECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDQ3-1", "uniprot_id": "Q9VDQ3_DROME", "id": "Q9VDQ3-1", "name": "", "aln": "--------------------------------------------------------------MRDSAAHASPAAAATSTQKWIVCRVCLQQ-----PKEPMASIFNDDSEKDLTHMIRECGGVPIK-------QFDHYPDKICEKCFKVLKMAFKFR--ETCQRSYGHLRQFVGPVEVEQRPPEKKGSETATKLEPDVDPDEAEQEPEHDEEDEDVDLDESHYAEADDAAETQGGVFHDEIEDGILVELEKDRIVHVKNEQVEEDGIIEEVYDVYET----YEGDLIPDQGYDHEMADQALSELSAEIEYLDQVEH-----DQLTESAHEDDAEVDLNSTEEEFVP-------SKSVRASIHARNATKRR-----------------VNPRRSATSTASVAVESSTSKTTDRGNPLKVRRGNSDSAGSKMS---IKSEKDISIGEVLARKHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIHERRGQSARESVAGLVSYDTANIVGLDM---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . . * :: : . . .: *:* . *::. * * .. * . . :* : : .* * * . ..: * * * :. . . : .: :. :: *.:: * :: . .. . : ..: . : :: ..: : . :: * : : :.. : : * . *. *:.* : : . ... .. : . *: * *:.. : * * * .* :: ** *. . . .. . : .: *. **.:: :.*. : : :: ** : . ::* *:* : *. **: :. :* *.:* :**:* **: *. **. *: :.:* * .**:*:*** * * .*. * :* *:**.*:*: *. *.* *: .**. *: ******:.* ***.* *: :* .** ** . . . . *.* .: ", "identical_positions": 99, "similar_positions": 164, "identity": "15.57%" }, { "cls_id": "homologset.agr.HGNC:32035", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA49-1", "uniprot_id": "D4AA49_RAT", "id": "D4AA49-1", "name": "", "aln": "-------MAWVKGAFLDVLLLLLLLLSAQTLPLVAAGDSHD-CDAPLASSLPQLSFSSSSQLSSSHGPGFARLNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYHQEES-ILGFPGNTNADSVVQYSLQPSFHTRFLRFLPLAWNPKGRIGMRIEVYGCSYKSEVVYFDGRSSLLYKFDKGAIRPIREIISLKFKGMQNSGIIFHGKGRHGNHIALELIKGKLVVYLSSGNGNLPPVNSIMNFTLGSLLDDWHWHSVLIEILNYHVNFTLDKYTHHVHVNKESNYLDLDFEISFGEILMPEGHLLTSPHKNFHGCLENVYYNGVNIIKLAKKHEPQ----ILIKGNVSFTCPQPQTVPVTFQSSGSYLALPGSLREDKMSLAFQFRTWNKAGRVFFSQPEHGSGSLVLFLTNGKLRLSLSEPGQPLQNIT-TGAVLNDGLWHSVSLTAEGRYLSLVVDGDFSAQALMSVGIHLGDTYYFGGCPNNSSSSGCESPYGGFQGCLRLISIG-DKVVDPIAVQQGVLGGFSDLQIDSCGIIDRCLPNYCEHGSGCTQSWDTFSCDCDGTGYTGTTCHSSIYEQSCEAHRHRGSPSG--LYYIDVDGSGQLAPFLVYCNMTADTAWTVVQHGGPDVMTVRGGPEGHTRSAT-FSYAATAAQLRAVVDTADHCEQQVDLQCRTSGPSDIGDGT----SLSWWVGRTNETYTYWGGSLPDPQKCTCGLEGNCIDSQYHCNCDADRNEWTSDTIVLSHKEHLPVTEMVVTDTGRPHSE--AAYTLGPLLCQGDKSFWNSASFNTEASYLHFPTFHGELTADVHFLFKTTISSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCELTVQSLTPFNDNRWHHVRAERNVKGASLQVDQLPQKTQPNPADGHVRLQLNSQLFIGGTASRQKGFLGCIRSLQVNGIALDLEGR-AIMTPGVEPGCPGHCSSYGHLCRNGGKCQEKRRGIACDCAFSAYDGPLCSHEISAYFEMGSSVTYNFQERPPLDENTSSLASSLHGDVILSRETITLSFRTTQTPCLLLYVSS-FDEEYLSVILANNGSLQVRYKLDRHRNADAFNFDLRNLADGHFHQLMINREEAVVSVEVNQST----KRQVILSSGTEFNAVKSLTLGKVLEPLDVDPETQQAAAQGFTGCLSSVQFGLEVPLKAALNQD-LTRVTIQGGVTAAAHCAEG--PGSAVWKLSPGPSMGAGHSGSVEDRQPLPNTDRSDPGVIGGITAVVIFILLCASAIAIRVHQQRR-LHQKNESTVSKTEEC------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PY62-1", "uniprot_id": "E9PY62_MOUSE", "id": "E9PY62-1", "name": "", "aln": "-------MARVNGAFLDALLLLLLLS-VQTLPLVAAGDPHN-CDAPLASSLPQLSFSSSSQLSSSHGPGFARLNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYHQEES-ISGFPGNTNADSVVQYSLQPSFHTRFLRFLPLTWNPKGRIGMRIEVYGCSYKSEVVYFDGQSSLLYKFDNGAIRPVREVISLKFKAMQNSGIIFHGKGQHGTHIVLELNKGKLVVYLNSGDGNLPPVNSIMNFTLGSLLDDRHWHSVLIELHNMHMNFTLDKYMHHVHVNKETSYLDLNFEISFGEILMPGGRFLTFPHKNFHGCLENIYYNGVNIIKLAKKHESQ----ILIKGNVSFTCPQPQTIPVTFLSSGSYLALPSSLREDKMSLAFQLRTWNKAGHVFFSQVGHGSGSLVLFLKNGKLILNLSEPGQPLQSIT-TGAVLNDGLWHSVSVSAKGSYLSLLVDGDT-AQTLMSVEIHLGDTYYFGGCPNNSSSFGCEHSFGGFQGCLRLISVG-DKVVDPIAVQQGVLGSFSDLQIDSCGIIDRCLPSYCEHGSRCTQSWDTFSCDCEGTGYTGTTCHSSIYEQSCEAHRHRGSPSG--LYYIDVDGSGPLAPFLVYCNMTADTAWTVVQHGGPDVVTVRGGPEGHMHSAT-FSYAANAAQLHAVVNVAEHCEQQVDLQCRTSGPSDTGDGT----SLSWWVGRSNETYTYWGGSLPNPQKCTCGFEGNCIDSQYHCNCDADRNEWTSDTIVLSHKEHLPVTEMVVTDTGRPYSE--AAYTLGPLLCQGDKSFWNSASFNTEASYLHFPTFRGELTADVHFLFKTTISSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCELTIQSPTPFNDNRWHHVRAERNVKGASLQVDQLPQKTQSTPADGHVRLQLNSQLFIGGTASRQKGFLGCIRSLQVNGMALDLEER-AVMTPGVEPGCSGHCSSYGHLCRNGGMCQEKHRGIACDCAFSAYDGPLCSYEISAYFETGSSVTYNFQEYSTLSANTSYLASSLHGDVILSRETITLSFRTTQTPCLLLYVTS-FYEEYLSIILANNGSLQVRYKLDRHRNADAFNFDLRNLADGHFHQLTINREEAVVSVEVNQST----KRQVILSSGTEFNAVKSLVLGKVLEPLDADPETQQAAAQGFTGCLSSVRFGLEVPLKAALNQN-RARVTIQGSVAAAAHCAEG--PGSAERKLSPGPSMDAGHSGSAEDRQPLPNTDRSDPGVIGGITAVVIFILLCVSAIAIRVHQQRR-LHQKNESTVSKTEEC------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NU0-1", "uniprot_id": "CNT3B_HUMAN", "id": "Q96NU0-1", "name": "Contactin-associated protein-like 3B", "aln": "-------MASVAWAVLKVLLLL----PTQTWSPVGAGNPPD-CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREES-IWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSP-GRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQ----ILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVT-AGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIG-DKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSG--LYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGT----PLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSE--ADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEER-ATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSS-FYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSA----KKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGCAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRK-LRKENESKVSKKEEC------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1Z8-1", "uniprot_id": "A0A8M2B1Z8_DANRE", "id": "A0A8M2B1Z8-1", "name": "", "aln": "-------MDLRGSHTIGMILPLY-----LIFPFITGSTSKESCDSPLVSGLPQSAFTSSSELSSSHGPGFAKLNRRDGAGGWSPLDSNKYQWLEIKLEQRTEITGVSSQGRYGSSDWVTRYLLMFSDTGHNWRPYRQEDS-IGAFSGNSNADSVVMYKLQQPVVAQYLRILPLDWNPNGRIGLRLEAYGCQYRSDVAGFDGAAHLLYRPDPGVNPADKDMLSMNFKTMQSSGLLLHMEAHSGHTLTLDLFKGRLVLQLRKG--RALSADFHPLWSVGSLLDDQHWHHVSIERVRGLVNFTVDKNTQQFQLPEYWSRSEID-EISVGG-SSPSGLQKSHSRRNFHGCLENVFYNGVSVIDGAKEKR------VAITGNVSFACSESIEVPVTFAGPRSFLAVPWVSGGESVSVSLEFRTWNKAGLLMTFDLQQNAGTLWLYLSEAKARLQIQKSGRILTDVT-AGVNLNDGQWHRLELAIRRGRLAVTVDQTDSSAVATSVFAAPDSVLFLGGCPGDGS--GCRNPFNVFQGCMRLIRTD-GALVDLIKVQQMLLGNFSDLQMDVCGIVDRCSPNHCEHGGKCSQSWSTFHCNCSATGYSGATCHSSIYEASCEAYKHKGNTSG--FYYIDVDGSGPIKPQLIYCNMS-DKAWMVIQHNNTELTKLKTS-SGINQHLAHFNYSADAEQIRAVISQSEHCEQELSYHCRKSRLLNTPDGA----PFSWWVGGSGEAHMYWGGAVPGSQQCACGLQGNCVHPEHFCNCDADSKDWSNDSGLLAHKEHLPVQSLALGDISRSGSE--AAYRVGPLQCYGDGNFWNTAYFNKETSYLHFPTFHGELSADISFLFKTSSSSGVFLENLGFKDFIRIELSSPTEVVFSFDVGNGPLDVRVQTPSALNDERWHHVRAERNVKEASLCVDQHPAAVQKAPADGHIHLQLNSQLFVGGTASRQKGFLGCIRSLKLNGRTLDLEER-AAITPGVSAGCPGHCSSYGGLCLNHGSCVEKYSGFTCDCSLSPFTGTFCHKELSAFFKPGTSVTYTFKEPYELNRNISAQSSSIYSDLTLRGENISLSFRTSQAPALLLYVNS-YYREYLSILLNRNGHLDVKYKLAHSREAEVFRASGRNLANGQLHRVSVQRLAETLSIQVDQHE----KEEFNLTSDTEFNAIKSIVIGKVLDSGEVDPEIGRLNALGFTGCLSVVQFNSISPLKAALLYPDTSPVIVTGSLSESG-CGSSLLSNPHAAETTHSLTDHVGTVG---TGEPIVNAINGDSALIGGVIAVVIFVSLSALAVTARFLYRRKETFQSQEPKAGKTDDSPETPFNTDPNSQSIISDNQKEYFI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94887-1", "uniprot_id": "NRX4_DROME", "id": "Q94887-1", "name": "Neurexin-4", "aln": "MRPPRSNTKAAFSSLQFGLLCLLLLVNNGIKSVQADAFTDYFSDYDCNQPLMERAVLTATSSLTERGPDKARLN---GNAAWTPVENTYNHFLTLDLGDPRMVRKIATMGRMHTDEFVTEYIVQYSDDGEFWRSYVNPTSEPQMFKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDR--ISMRVELYGCDYISENLYFNGTGLVRYDLRREPITSTKESIRFRFKTAFANGVMMYSRGTQGDYYALQLKDNKMVLNLDLG------SRVMTSLSVGSLLDDNVWHDVVISRNQRDIIFSVDRVIVRGRIQGEFTRLNLNRELYLGG--VPNVQEGLIVQQNFSGCLENIYFNSTNFIRVMKDSTELGEGYLFTRVNTIYACPSPPIYPVTFTTRSSFVRLKGYENSQRLNVSFYFRTYEETGVMLHHDFYSG-GYLKVFLEFGKVKIDLKVKDKARIILDNYDDQFNDGKWHSFVISIEKNRLILNIDQRP-MTTTKSMQVATGAQYYIAGG----------KDKNGFVGCMRLISVDGNYKLPQDWVKGEEVCCGDDVVVDACQMIDRCNPNPCQHKGLCHQNSREFFCDCGHTGYAGAVCHTSNNPLSCLALKNVQHVQQRVNLNLDVDGSGPLEPFPVTCEFYSDGRVITTLSHSQEHTTTVDGFQEPGSFEQSIMYDANQLQIEALLNRSHSCWQRLSYSCRSSRLFNSPSEAGNFRPFSWWISRHNQPMDYWAGALPGSRKCECGILGKCHDPTKWCNCDSNSLEWMEDGGDIREKEYLPVRAVKFGDTGTPLDEKMGRYTLGPLRCEGDDLFSNVVTFRIADASINLPPFDMGHSGDIYLEFRTTQENSVIFHATGPTDYIKLSLNGGNKLQFQYQAGSGPLGVNVGTSYHLNDNNWHTVSVERNRKEARLVVDGSIKAEVREPPGPVRALHLTSDLVIGATTEYRDGYVGCIRALLLNGKMVDLKEYSKRGLYGISTGCVGRCESN--PCLNNGTCIERYDGYSCDCRWSAFKGPICADEIGVNLRSSSIIRYEFEGSFRST----------------IAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEIIFPKKHFGLGQYHDMHFMRKNGGSTVVLKVDNYEPVEYNFDIKASADAQFNNIQYMYIGKNE-----------SMTDGFVGCVSRVQFDDIYPLKLMFQQNPPKNVKSLGTQLTEDFCGVEPVTHPPIEIETRPPPLVD-------EEKLRKAYNEVDSVLLACLLVILFLLLILMFFLIGRYLHRHKGDYLTHEDQGADGADDPDDAVLHSTTGHQVRKRTEIFI--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * . . . .* . * . :. :::. :.:**. ::** * ..*:*: .. ::* :.* : : ::: * :.::** *:: :** *. *: * . * * **::.:*: :: .. ::::*: * *: . *.:*:* *** * *: *:* . : * . :: : :.** .*:::: .. * .*:* ..::*. * * ::****** ** * *. : *::*: : : . ::: *: .* * ::.* *****:::*.... *. : *. ::*... **** *:: : : :.::: :**::.:* :: : . * : ::* .* :.: .: : . :*** ** . .: . : : :* :: . ::.* . * **:*** . . : *: : *: :* * : *** *. *:* . * *. * *:* ***:* .**:* ** * :: . :*.**** : * : *:: * . . : . . . : * * *:.* :. :. * *.: * .: : . : .:***:. .:. *.*::*..::* **: *:* .. ****:. :* .* : .**:*** : . * . . .* . * :*** * ** * * . *. : :::*.* :.*: : *:*: ...*::. * .*:*::.* . .:: *.::.*.** : : : :**:.** * .*** * * * ** *.. *:*.*:*.:*.*: : *::****:* :** :**: *:..** *:*.: * * * * *: * :*** *.: *.:* *:.. : .: : * *: * * :.* *: . :** ..* ***:: : ..* * :.: :: * . .:.: : :. :. .: ::*:: : :. ::.::** :: : :** : **.**:* *:*. *** : * * *. . . : . : . *. ::. : .: ::: : : * ::: :* .. : ", "identical_positions": 271, "similar_positions": 395, "identity": "20.12%" }, { "cls_id": "homologset.agr.HGNC:32036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VIV9-1", "uniprot_id": "Q9VIV9_DROME", "id": "Q9VIV9-1", "name": "Nudix hydrolase domain-containing protein", "aln": "--MSQPASPTKWRTSASVILVSRDD-GNNK----------DYKVLMLKRSDATAIALNQTVFPGGLLDSGADESVAWLHYLEEFGVPQEALRRLVLIREDRPAILAPQGTGCYDRFFKRSRIWAREITLRLTAVRECFEEVGLLLCRSRSQLDFG------AVTCAQAVPDLESWQRRVHNKPAEFLTLCRELNVVPDLWALHEWSAWASPGFI--RKGHETVFFMAFVDKQP---ELLEEPSEVKETLWLTPVELLRLADLGNVWFMPPQVYELSRLMGIKAYQSLLEFAIKRSGLGTTMFLPIGYNCQGSMVFVLPGDDFYVPEPHLVHEIISFPGSEEEFRARS-KHLHRYT-YGPGVRNLELNIAPPNGHLKPLKFQAERQKL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIV5-1", "uniprot_id": "Q9VIV5_DROME", "id": "Q9VIV5-1", "name": "", "aln": "----MTTKTGTYRPSASLIVAAKEDSLEDY----------DYRLLLIKRTEKTSYALNHCVFPGGVFDPIEDQSAKWITFFKSFGVTDEQLKMCRHNQD------SPR-----PEFLSGGDHISRDIALRLTALRETFEEVGILICTEQDDIQKWDSKSGHPRTVLLESSEHFEWQHRVHNDASQFLELFRHYKVIPNIWSLQEWSIWRTAATA--NRKYDTVYYITMLDKYTRNIKLLLEPHEVASAHWLSPIEAWSSSQKAIIWLPFMLLYDIARLMNFYSFQELLNFSRQRSCNGSTMVQPVYYRCDDCMFGVLPGDELYPKEPGACTQTIILSGSVDDLHRKS-KQYNRYIVYDFHKVVLASNIPPCDGHLPLQPLVNNKLAKL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIV6-1", "uniprot_id": "Q9VIV6_DROME", "id": "Q9VIV6-1", "name": "Nudix hydrolase domain-containing protein", "aln": "----MSRLLPKIRSSSSLILLAKNQVEKSTSC--------DYNALLLTRTQKSTFMPESSVFPGGVCDAS-DSSPAWLEHFQRNEFSAAKLRNVGHVKGPRPDIFHTK---------ADKKSLDPSLALRLTAIRETFEELGILLCRDSKSLTSTS-----DYGAFYDQFDRAHWQHIVHNNASQFLELCKQLDVLPDVWSLHEWSVWRTPSTF--KKRFETAFFMTALEQEP---RVHIEPNEVKDSAWRSPLDYLQASLRKELWLPPPQFYELSRCLNFSSLDNLRQFAAEREVKGIQLIHPVVHKCTNGLVHLLPGDDAYPADPDASNEKIEIDLSVEEFRSKTNAKLHRSEHWNQHQSQLIIKFERDDGQVHPLDPTKL-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6AYD9-1", "uniprot_id": "NUD19_RAT", "id": "Q6AYD9-1", "name": "Acyl-coenzyme A diphosphatase NUDT19", "aln": "MS-----GPSSWRRAATVMLAAGWS---HASP-------AGFRLLLLQRAQNQRFMPGAHVFPGGVLDAADSSPDWVSLFAPRHTPPRFGLGPEPPRQPSFPGLF---------HGDADGAALPDDVALRICAIRETFEEAGVLLLRPRDSAR-ASQE---PSIALSPPAGLADWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWGGWLTPYGR-SSRRFDTTFLLCCLRETP---RVEPDLAEVVGYKWLSPSEATECFLSKEIWLAPPQFYEVRRLENFASLSALYRFCLDHPLEVPEKWLPIVLLTSDGSIHLLPGDELYVKGSDFLEKNMSIDKKTEEIVTEG-KVVNRIVIHSPHLYEIYMTLTSKSEHGYPKSYTAKKSCTARL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11930-1", "uniprot_id": "NUD19_MOUSE", "id": "P11930-1", "name": "Acyl-coenzyme A diphosphatase NUDT19", "aln": "MS-----SSSSWRRAATVMLAAGWT---HSSP-------AGFRLLLLQRAQNQRFLPGAHVFPGGVLDAADSSPDWVRLFAPRHTPPRFGLGPEPPRQPPFPGLS---------HGDADPAALPDDVALRICAIREAFEEAGVLLLRPRDAAP-ASQE---PSQALSPPAGLAEWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWGGWLTPYGR-TIRRFDTTFFLCCLRDIP---RVEPDVAEVVGYQWLSPSEATECFLSKEIWLAPPQFYEMRRLENFASLSALYRFCSDRPSEVPEKWLPIILLTSDGTIHLLPGDELYVKDSDFLEKNMSTDKKTEEIVKEG-KVLNRVVIHSPYVYEIYMTLPSENKHVYPRNYIVNKRCTAHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MXV4-1", "uniprot_id": "NUD19_HUMAN", "id": "A8MXV4-1", "name": "Acyl-coenzyme A diphosphatase NUDT19", "aln": "MSSSLRPGPSRWRRAASIVLAAGWSRPETATPPSRPPPAEGFRLLLLQRSPHQGFMPGAHVFSGGVLDAADRSADWLGLFAPHHGPPRFGLGPAPFSRTAFPSLPDTD-----DHKTDNTGTLPEDVAFRICAVREAFEEAGVLLLRPRTSPPGPAPG---PGLALEPPPGLASWRDRVRQDPRHFLRLCAHLDCTPDIWALHNWSAWLTPFLRGTTRRFDTAFFLCCLREPP---PVYPDLAEVVGYQWSSPSEATESFLSKEIWLPPPQFYEVRRLANFASLSDLHKFCLGRALEGLERWLPIILLTADGMVHLLPGDELYLEDSDFLENLMSTEKKTEEIMKEG-KQFHRIVTYHRHLYDIHVTVQPKYKHVYPKNSVVRKSHL---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::::: : .:. *:: *: **.**: *. .. . . * : .:::*: *:** *** *:*: *: *:... ** * . . *::*:*::*. * :. : .:*.: : : . . : : ** * :* : :*: .*:: * .: : . * .*. : *: . . :****: * . : : . ::: . :* : .. : ", "identical_positions": 45, "similar_positions": 87, "identity": "11.54%" }, { "cls_id": "homologset.agr.HGNC:32037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCR8-1", "uniprot_id": "D3ZCR8_RAT", "id": "D3ZCR8-1", "name": "", "aln": "MVVLALTLLVDAVAVFLLGSVLWVICRHLWTEHIPEGITHPMRLRVLSCLLQLSLTWGMLFEKLGLCYAPQFASFLH-DLMPLKKDP--DVVVKDVHFETIPVKLYKPKKPSSVPRIGIIFFHGGGTILGSLRTHHSICLRLSKDCDAVVISVGYRKSPMYKYPVMKDDCVAATTHFL-RSLDVYGVDPDRLVVCGDSVGGTAAAVTSQTVVHRKD--LPQIRAQILIYPSLQLVDFGSPSYQQNFNVPLLTSNLALYCFCCHLDVKLSWQSVIKSGRHLPPEIWEKYRKWLGVENIPERFKKQGYKPIPRGPVNNEVYQEIKTALNNTCSPLLAEDSLVSQLPETCIVSCEYDLFRDHSLLYKKRLEALGVPVTWHHMEDGFHGVLNTFEFGLLSIPCSLRIMDLIIRFIKKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A7Z8-1", "uniprot_id": "ADCL3_MOUSE", "id": "A2A7Z8-1", "name": "Arylacetamide deacetylase-like 3", "aln": "MVVLALTLLVGSVAVFSLGSLLWVVGKHFWTEHIPEGITHPWRLRILSCLFHLTMTWGMIFEKLGLCYAPQFASFLH-DLKPLKRDP--DVVVKDLHFGTIPVKLYKPKKPSSIPRLGIIFFHGGGTIIGSLRTHNSICLRLSKECDSVVVSVGYRKSPMYKYPVMKDDCVVATTHFL-ESLDVYGVDPARVVTCGDSVGGTAATVTSQMLVHRPD--LPRIKAQILIYPLLQLIDFGSPSYQQNRNIPLLSWDLAFYCFCCHLDVNISWKSVVKNGMHLPPDVWEKYRKWLGAENIPERFKNRGYKSIPWGPVNNDAYQEIKRSLNYTCSPLISEDSIVSQLPETCIVSCEYDLLRDHSLLYKKRLEDLGVPVTWHHMEDGFHGVLSALDYGLLSFPCASRIMDLIIQFIRKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VUY0-1", "uniprot_id": "ADCL3_HUMAN", "id": "Q5VUY0-1", "name": "Arylacetamide deacetylase-like 3", "aln": "MWDLALIFLA-AACVFSLGVTLWVICSHFFTVHIPAAVGHPVKLRVLHCIFQLLLTWGMIFEKLRICSMPQFFCFMQ-DLPPLKYDP--DVVVTDFRFGTIPVKLYQPKASTCTLKPGIVYYHGGGGVMGSLKTHHGICSRLCKESDSVVLAVGYRKLPKHKFPVPVRDCLVATIHFL-KSLDAYGVDPARVVVCGDSFGGAIAAVVCQQLVDRPD--LPRIRAQILIYAILQALDLQTPSFQQRKNIPLLTWSFICYFFFQNLDFSSSWQEVIMKGAHLPAEVWEKYRKWLGPENIPERFKERGYQLKPHEPMNEAAYLEVSVVLDVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKKRLEDLGVPVTWHHMEDGFHGVLRTIDMSFLHFPCSMRILSALVQFVKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NVX1-1", "uniprot_id": "A0A8M1NVX1_DANRE", "id": "A0A8M1NVX1-1", "name": "", "aln": "MNTATAILISAFAALFAA--FCLLVYFELRNVNIPPGVDSPAKLRVIHCTYMGITCLGYILERLGLCHQYNFVGWCRCHIMTCKRSVPHGLRIKDLTFSTVPVRVYEPTAASGEKKRGLVYFHGGGWMFGCIDDYDEVCQHISLKSNTTVVSVGYRLAPEHRYPAHLDDCEVATRHFLSIAATDFGVDPCRVAVGGDSAGANLAAALCQRLSKTQDGHLPSPCAQVLIYPALQMADFHLPSYQQNHSVPILFRGRTVFYFLQYLNGNTSVSQQILEGRHVPAELKLRYKKWLDPNSLPPQFIKQARCQQDLSSHDADVYHIVKQGLDPEISPLLAEDDVLRLVPPAFVLTCEFDVLRDDGFLYQKRLRDLGVDVTWEHLPEGFHGVISFFNQGWLTFQSSQRGLDSIVRYVKSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :: ..:* :: .: . :** .: * :**:: * * ::*:* :* :* : : .: . * . .: :.*. * *:**::*:*. .: : *::::**** ::*.: :. :* ::. ..::.*::**** * :::*. ** .** *** : :**** *:.. *** *. *:. .* : . * ** **:***. ** *: **:**. .:*:* . : * *: . * .. : .* *:*.:: :*:***. :.:* :* ::. . : .* :. *: ***::**.:: :* : :::**:* :**..:**:***. *** ***.*: :*****: :: . * : .: * :. :::::: :", "identical_positions": 114, "similar_positions": 150, "identity": "27.54%" }, { "cls_id": "homologset.agr.HGNC:32038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5XWI7-1", "uniprot_id": "A0A8I5XWI7_RAT", "id": "A0A8I5XWI7-1", "name": "", "aln": "-----MAVLWLLLLVGLSIFLLGVFIWAVVKHFLTAEISSSLQHPVKLRLMQCVVLFTIALGNILQKLRICSMPSFIKFLHDLRGR-KKDPT--LVVTNMHFGTIPVRLFQPKAVSSNLRRGIIFFHGGGALFGSLNLYHRLCSFLARETDSVLLSVGYRKLPDHHHPVIHLDCLNASIHFLKNLQT-YGVDPSRVVMAGESVGGWAVATVTQALACQDK--LPQIRAQVLITPILQGVNFQLPSQLQKRNVPLLTRDLMITFFCRYLNIDLSWKNAILTGACVPPDMWKKYSKWLSSDNIPQRFKGKDFSPEFLGPFNETAYLETKHVLDEKISPLLADDKIIAQLPDTFLLSCEHDILRDDTLLYKKRLEDQGVPVTWHHVEDGFHGCIIFFDNQFFSFPCSMNALNPTISYIKGI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A340-1", "uniprot_id": "D4A340_RAT", "id": "D4A340-1", "name": "", "aln": "-----MAVLWLVLLGGMLTFFLGVFVWAFIQHLLTVEIPSTLKHPVKLRILHFSFQYLINLGTILEKLRICSTPAFLLCIQDLVIIIKKDPN--MLVTDTRFGTVPVRLFKPKKVSSKLRRGIIFYHGGGGLFGSLDVYHGLGNFLARETDSVVLLVGYRKLPDHRHPVIHLDCLNASIHFLKNLQT-YGVDPSRVVIAGESAGGWAVATVTQALSCQDK--LPQIRAQVLITPVLQGVNFQLPSQLQKHNVPLLTRDLMITFICSYLSIDLSWKNAILTGACVPPDMWKKYSKWLSSDNIPQRFKGKDFSPEFLGPFNETAYLETKHILDEKISPLLADDKIIAQLPDTFLLSCEHDILRDDTLLYKKRLEDQGVPVTWHHVEDGFHGCIIFFDNQFFSFPCSMNALNATISYIKGI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVU7-1", "uniprot_id": "B1AVU7_MOUSE", "id": "B1AVU7-1", "name": "", "aln": "-----MAGFWLVLIGGLLTFFLGVFVWVFIQHLLTIEIPSTLKHPVKLWILHLIFQYLITLGTILEKLRICSMPAILQFFQDLIIIKKKVPN--VIVTDTRFGTVPVRLFRPKEVSSKPRRGIIFYHGGGAVCGSLDFYHGLGNVLAHETDSVVLLVGYRKLPDHHHPVVYLDCLNASIHFLKNLQT-YGVDPSRVVISGESIGGWTVATVTQALVSQAI--LPQIRAQVLITPGLQGINFQLPSHQQKQNVPLLTRDLVITFVCRYLSIDLSWKNAIVTGAFVPLDTWKKYSKWLSSDNIPKRFKSKKFHPEFLGPFSETAYLETKHVFDVNISPLLADDKIIAQLPDTFLVSCEHDVLRDDALLYKKRLEDQGVPVSWYHAEDGFHGCISLFDKQPFSFPCSMNVLNAVISYIKDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1ASB3-1", "uniprot_id": "B1ASB3_MOUSE", "id": "B1ASB3-1", "name": "", "aln": "-----MSVLWLVLLAGVSTFFLGVFVWAIIQHFLTVEIPSTLKHPAKLRFLHCMLLYLITLGNILEKLRICSIPRFLQFVQDLILI-RKNSN--VAVTDMHFGTVPVRLFKPKEASSKYRR---------------DTYHGLGSFLAHETDSLVLLVGYRKLPDYHHPVPFKDCLNATIYFLKNLEI-LGVDPSRVVLCGDSLGGWAVATVTQVLTSMPN--LPRIQTQVLIYPILHFINFQLPSYQQNKNVPFLTRDMLLMCVCKYLAIDLSWTDAMSTGAVIPLDKWKKYRKWLSYDNIPRRFWRQDTQPEVLGPFNEAAYLETKHVWNAEISPLLADDKIIAQLPKTFLVSCEHDVLRDDALLYKRRLEDQGIPVSWYHAEDGFHACINLFDKQPFSFPCSMKVTNAVARYIKDMC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTU9-1", "uniprot_id": "D3ZTU9_RAT", "id": "D3ZTU9-1", "name": "", "aln": "-----MAVLWLVLLVGLSTLNLGVFIWAAIHHFLTAEIPSALKHPVKLRFLHCVVLYVIALGKIFEKMKICSMPRFIQFFQDLIII-KKNHN--LVVTNMCFGTISVRLFQPKAVSSELRRGIIFYHGGGALCGSLDSYHNLCSFLAQQTDSVVLSVGYRKLPDHSHPCITKDCLNASIYFMKNLMT-YGVDPSRVVACGESIGGGAVALVIQALLSFPS--LPRIRAQVLITPVMQAVNFRLPSHQQNQNVPFLTNDILMIAVCKYMDIDFSWKDALLNGTYMPLDSWKKYSKWLSSDNIPRRFKSKSLLPEFSGPFNETAYLEIKHILDTEVSPLLVEDKIIAQLPQAFLVTCENDPLRDDALLYKKRLEDQGVPVTWYHVEDGFHGCIFLFDTHLFSFPCSIKIAKAVSSYIKGI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVU5-1", "uniprot_id": "B1AVU5_MOUSE", "id": "B1AVU5-1", "name": "", "aln": "-----MAIPWLVLLVSLSTFYLGVFIWTVIQHFLTVEIPSALKHPVKFRLLHCLMLYIITLGNILEKMKICSMIRFIQFFQDLIVI-KKNHN--LVVTNMHFGTIPVRLFQPKAVSSEGRRGIIFYHGGGAICGSLDCYHNLCSFLAQQTDSVVLSVGYRKLPDHHYPCISKDCLNASIHFLKNLMT-YGVDPSRVVACGESIGGGTVALVTQALVSFPS--LPHIRAQVLITPSMQAINFRLPSHQQNQNVPFLTRDILTIAVCKYLDIDLSWKDALFNGTYMHPDTWEKYRKWLSSDNIPRRFKNKSLLPEFSRPFNEAAFLEIRHNSGLEVSPILVDDKIIAQVPEAFLVTCENDPLRDDALLYKKRLEDQGVPVTWYHVEDGFHGCILLFDKQPFSFPCSIKIANAVASYIKGI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1AVU6-1", "uniprot_id": "B1AVU6_MOUSE", "id": "B1AVU6-1", "name": "", "aln": "-----MAVLCLLLLVGLPTFLLGVFIWAVVKHFITAEIPSSLQHPVKFRCMHCLMLFIMALGNILQKLRICSLPSFIIFMHDLVPI-RKDPT--LVVTNMHLGTIPVRLFQPKAVSSKLRRGIIFYHGGAAAFGSLDIYHNLCSFLVRETDSVLLSVGYRKLPKHHHPAALNDCLSATILFLKALET-YGVDPSRVVLCGDSFGGWVVASISQTLVSTPS--LPQIRAQVLIYPILQVINFLLPSLQQNKNIPLLSKDLLIIFVCNYLAIDLSWGDSMLTGAVIPLDKWKKYRKWLSSDNIPRRLWSQDTQPEFLGHFNEAAYLETKHIFNPEISPIIADDKTIAQLPEAFLVSCEYDIVRDDTLLYKKRLEDQGVPVTWHHVMDGFHGCVLLFDRKFLSFPCSIKVVNTVVSCIKSI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VUY2-1", "uniprot_id": "ADCL4_HUMAN", "id": "Q5VUY2-1", "name": "Arylacetamide deacetylase-like 4", "aln": "-----MAVPWLVLLLALPIFFLGVFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIFEKLGICSMPKFIRFLHDSVRI-KKDPE--LVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALET-YGVDPSRVVVCGESVGGAAVAAITQALVGRSD--LPRIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRGYQPWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZBA8-1", "uniprot_id": "D3ZBA8_RAT", "id": "D3ZBA8-1", "name": "", "aln": "MNMNSMLYLVGFLLATMCLLVLGVNVWVLIDDLRTIDVPPSVLHPVKLRILHYGFHLTTTWGNIFEKMKICSMSQFVCFVQDSLAP-KENLG--MFVKDLHFGTIPVRIFHPKAASSKPRRGIIFCHGGGALIGSLDSYHNLCAFLARETDSVLMSVGYRKLPYYHHPSLYYDCLNASIHFLNSLKV-YGVDPSRVVICGDSIGGAVAAIVTQTLSSRTD--IPKIRAQVLIYPVLQAFYFQSPSHLTNINIPFLTQEFFITCVCKYLAIDLSWKDTMLTGASISPSAWKKYEKWLSPENIPKRFKTEYRPPESPTPFNDAAYLETKHAMNVDISPLLADDKIITQLPEAFIVSLHWDIVRDDVLLYKKRLEDHGVPVTWHHVVDGFHGCMLLFDKKFFSFPCSVNIMHAVVSYIKGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BM81-1", "uniprot_id": "AD4F1_MOUSE", "id": "Q8BM81-1", "name": "Arylacetamide deacetylase-like 4 family member 1", "aln": "-----MLYLVGFLLATVCLLVLGVNVWVLIDHFLTIDVPPSIPHPVKFRILHFCFHLTTTWGHILEKMNICSMPQFFCFLQDSLSS-KENHG--VFVKDLRFGTIPVRLFRPKAASSKPRRGILFFHGGGAMIGSLDSHHNLCTFLARETDSVLVSVGYRKLPYYHHPSLYHDCINASIHFLKSLKA-YGIDPSRVVICGESIGGAAAVVVTQTLLSRTD--IPKIRAQVLIYPILQAFYFQSPSHLMHKNIPFLTKDFMITCICKYLAIDFSWKDAMLTGACISPSAWKKYEKWLSPDNIPKRFRTTYQPPESPAPFNEAAYLETKHAMNIDISPLVADDKIIAQLPEAFLVSLHWDIIRDDVLLYKKRLEDQGVPVTWHHVEDGFHGCILLFDKKLFSFPCSLNIVNAVVSYIKDL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2A752-1", "uniprot_id": "A2A752_MOUSE", "id": "A2A752-1", "name": "", "aln": "------MILMITLFTTATFLVLGVSVWVLIKEILTVHVPPPIPQRVKFHMLHYFFQLTIALGNVLEKMKICPMPRFFCFIQDLLVS-KNNFG--VLVKNMHFGTIPVRLFQPKATSSGPRKGIIFYHGGGGVFGSLDSYHNTCSYLAHETDSVVMAVGYRKLPDHHHPTAYHDCLNATVHFLKELKT-YGVDPARVVVSGESIGAGAAAIIAQVVLARKD--LPQFRAQVLINPVVQGVNFQLPSYQQYSDVPFLSRKFLMTCACKYLAIDQSWKDAMLKGTFIPPDHWKKYAKWLSSDNIPQRFKSQGRQPEFPGPFNESAYLETNHIFSLETSPLLADDKIIAQLPETFLVSSEYDVLRDDTLLYKKRLEEQGVPVTWCHLEDGFHGCIVLFDKNALSFPCSKKAMSSTVSFIKGI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1NVX1-1", "uniprot_id": "A0A8M1NVX1_DANRE", "id": "A0A8M1NVX1-1", "name": "", "aln": "------MNTATAILISAFAALFAAFCLLVYFELRNVNIPPGVDSPAKLRVIHCTYMGITCLGYILERLGLCHQYNFVGWCRCHIMTCKRSVPHGLRIKDLTFSTVPVRVYEPTAASGEKKRGLVYFHGGGWMFGCIDDYDEVCQHISLKSNTTVVSVGYRLAPEHRYPAHLDDCEVATRHFLSIAATDFGVDPCRVAVGGDSAGANLAAALCQRLSKTQDGHLPSPCAQVLIYPALQMADFHLPSYQQNHSVPILFRGRTVFYFLQYLNGNTSVSQQILEGRHVPAELKLRYKKWLDPNSLPPQFIKQARCQQDLSSHDADVYHIVKQGLDPEISPLLAEDDVLRLVPPAFVLTCEFDVLRDDGFLYQKRLRDLGVDVTWEHLPEGFHGVISFFNQGWLTFQSSQRGLDSIVRYVKSL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.. .: . .:.. : .*: :: * ::::: :* :. : :. : :.: :.*:.**::.*. .*. :: : :. : :::: :: :*** * : * ** *: *:. *:**.**. *:* *. .. : * : :* :**** * :: : ** .:*:* . *: : * : : * : . :* ***. :.:* :: .. .: .: . . **::.:*. : :* :*::: . * :*** :**::**.: *: *:* * :***. : :*: ::* .* . . :*.: ", "identical_positions": 68, "similar_positions": 131, "identity": "16.23%" }, { "cls_id": "homologset.agr.HGNC:32043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UWJ8-1", "uniprot_id": "C16L2_HUMAN", "id": "Q6UWJ8-1", "name": "CD164 sialomucin-like 2 protein", "aln": "MEAPGPRA-----------------LRTALCGGCC-----CLLLCAQ----LAVAGKGARGFGRGALIRLNIWPAVQGACKQLEVCEHCVEGDGARNLSSCVWEQCRPEEPGHCVAQSEVVKEGCSIYNRSEACPAAHHHPTYEPKTVTTGSPPVPEAHSPGFDGASFIGGVVLVLSLQAVAFFVLHFLKAKDS-TYQTLI-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D6W7-1", "uniprot_id": "C16L2_MOUSE", "id": "Q9D6W7-1", "name": "CD164 sialomucin-like 2 protein", "aln": "MAAPGPRA-----------------LRAALCGGCC-----CLLLCAQ----LVLAGKGARGFGRGALLRLNVWPTTQGGCKHLGHCEHCVDR--AHNFSICVWQQCGPEEPGHCVAQAEVVKEGCSIYNHSESCPASHHHSTEEPKPSTTGSPPIPEDHSPGFDGASFIGGIVLVLSLQATAFFVLRFLKAKDS-TYQTLI-------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LYT1-1", "uniprot_id": "A0ABK0LYT1_RAT", "id": "A0ABK0LYT1-1", "name": "", "aln": "KEAGGWRCSSVSVTRPWGSSRPVQKFRSLYWERYCSLAPVFLLLSSHSQPPPPLSGKGARGFGRGALLHLNIWPAAHGGCKHLGHCERCVDR--AHNSSICVWQQCGPEEPGHCVAHTEVVKEGCSVYNHSESCPASHHHSTEEPKTSTTGSPPIPEDHSPGFDGASFIGGIVLVLSLQATAFFVLRFLKAKDS-TYQTLEENQ----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PHX2-1", "uniprot_id": "M9PHX2_DROME", "id": "M9PHX2-1", "name": "", "aln": "MNRQAKFL-----------------ILCLFVGLFSANLCEEVTTPAPADTTTQESKNTTTPPDTTTTVTPPSTSTTSTTTEKTTTTPPITTSTEKTTTSTTPASTTSSTTPASTTSSTTPATTTTTPGTTSTTTPSPNSTTTTPPPHTSTTPAPKPVPCG-HFDGSSFIGGIVLTLGLLAIGLVAYKFYKARNERNYHTLXAATAFTSAFNAAAGAAAASSSAASTDAERVRFVQPSIPLRSPPTQPPPPPPTHMGGSGGGAAAAPQNCSPSARDRLLHT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : : : : . : : .:. :: . . * . . *. .: : .. : . * : *:.: .* * :* ..* * . ***:*****:**.*.* * .:.. :* **::. .*:** ", "identical_positions": 28, "similar_positions": 51, "identity": "10.0%" }, { "cls_id": "homologset.agr.HGNC:32044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT12-1", "uniprot_id": "E9PT12_RAT", "id": "E9PT12-1", "name": "", "aln": "MTEKILEKFDALEEKARILAAIREKNSN--WRLKKKPLITPMLFDHHVKFGDTITPAAFKTVANITEDESNDLKKSKKSVSFKYKPK-PRSDFEESDLRPPTLATVINDEESKLMEHKEENLKPSSTSLRFLKDK-ETGNTKPLPLPLPRSRHPSKKSAESSILSPTLNKVSNA-----------DQNESRAKKSTHSTDHSADSSRNGRKHRPEVNNLITKESELTRNDQARMTHPVKQNILFPLDCEDLLKDPKMKTIDLGPTETVHTSMEQNHASPIIFYDTKYVQMLFQTK-WFTPYALN------YTKKNIVLEKNCEIVKTLFNDEPSTISKPESTKSVAQQKRLRV-LSGELAQKSISEKRKKKHDSLVSKKISPNPLYNLSQTFSSLSKRFVGYFDKDVIQEKSDKADKYEL-FSKTKPPPTRKFTTLPIKYDSKPLRNILEIRKLNNITPLDNLLG---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5Q8-1", "uniprot_id": "CA141_MOUSE", "id": "Q9D5Q8-1", "name": "Uncharacterized protein C1orf141 homolog", "aln": "MTEKILEKFDALEEKERILEAIRENNTDRHHRQRKKPLITPLLFDLHVQFGDTITPSASKIIK----NKPHDLKNPKRSVSFKYKPNNSRSDLEESDLRPPILGTMINYEESKLMDHKEENLKSRPISLRYLKDKDETEYANPLPFPQLWSKHLCKKSAESSVPTPKLTNESNASKKENVSPPFTDQHESRTKKSMHSTDHSADSSTSRGKCPPKG---ITKESELTRNDEARKPHPVKQSIMLPLDCEDLLKNPKIKTIDLRPAVTVHTSMKQSHANPIIFYDTEYVQMLFLTK-RFTPYAMK------CTERNIVLEKNYEVLKVLFSDEPSAVSEP------IQQKHLQV-FSAEYAQKSINEKRKKKHDRLVSKKISPNTRYNLSQTFSSLSKKFVGYFDKDVTQGKSYKANRFER-FSKTKPPPTRKLTTLPIKYDSKPLKNIFEIHKLNNMTPLDNLLGLRA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JVX7-1", "uniprot_id": "CA141_HUMAN", "id": "Q5JVX7-1", "name": "Uncharacterized protein C1orf141", "aln": "MAEKILEKLDVLDKQAEIILARRTKINRLQSEGRKTTMAIPLTFDFQLEFEEALATSASKAISKIKEDKSCSITKSKMHVSFKCEPEPRKSNFEKSNLRPFFIQTNVKNKESESTAQIEKKPRKPLDSVGLLEGD-----------------------------------------------------RNKRKKSPQMNDFN------------------IKENKSVRNYQLSKYRSVRKKSLLPLCFEDELKNPHAKIVNVSPTKTVTSHMEQKDTNPIIFHDTEYVRMLLLTKNRFSSHPLENENIYPHKRTNFILERNCEILKSIIGNQSISLFKPQKTMPTVQRKDIQIPMSFKAGHTTVDDKLKKKTNKQTLENRSWNTLYNFSQNFSSLTKQFVGYLDKAVIHEMSAQTGKFERMFSAGKPTSIPTSSALPVKCYSKPFKYIYEL---NNVTPLDNLLNLSNEILNAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:******:*.*::: .*: * * : . . :*..: *: ** :::* ::::.:* * : ::. .:.:.* **** :*: :*::*:*:*** : * :: :**: : *:: : *: *:.. ..: *** : .*.. **.: .** : :.*::. ::** ** **:*: * ::: *: ** : *:*..:.****:**:**:**: ** *:.:.:: .. *::**:* *::* ::.::. :: :* *:* ::: :* : .:.::.:* *** : . :: * *. **:**.****:*:****:** * : * ::.::* ** **.. . ::**:* ***:: * *: **:*******. ", "identical_positions": 127, "similar_positions": 150, "identity": "26.79%" }, { "cls_id": "homologset.agr.HGNC:32046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAE3-1", "uniprot_id": "LELP1_MOUSE", "id": "Q9DAE3-1", "name": "Late cornified envelope-like proline-rich protein 1", "aln": "MSSD---KSSDSKNGLKNCDPRCEQKCETKCQPSCLNKLLQRCSEKCSLDKCPPSPNCPPCPPCPPCPLVCQSQCSTPTSPLCPPLCSPRCSGTLACCPPSCPQKGCVKPCPPKCPSPCLPRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T871-1", "uniprot_id": "LELP1_HUMAN", "id": "Q5T871-1", "name": "Late cornified envelope-like proline-rich protein 1", "aln": "MSSDDKSKSNDPKTEPKNCDPKCEQKCESKCQPSCLKKLLQRCFEKCPWEKCPAPPKCLPCP--------SQSPSSCPPQP-CTKPCPPKC-------PSSCP-----HACPPPCPPPE----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** **.*.*. *****:******:*******:****** ***. :***..*:* *** .** .* *..* *. *.*:* *.*** :.*** **.* ", "identical_positions": 62, "similar_positions": 22, "identity": "50.41%" }, { "cls_id": "homologset.agr.HGNC:32057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5H5-1", "uniprot_id": "D4A5H5_RAT", "id": "D4A5H5-1", "name": "", "aln": "MSFNDQQCKQPCVPPPCLQKTQEKCQAQAEDVCVPSCQDPCQDKCPQQAQETCGPQCQELSQGNCPQQGQDPCPPPSQDQCLPQCADPCQELAQTKCVEEFPQKALEKCSAQSKGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BV84-1", "uniprot_id": "PRR9_MOUSE", "id": "Q8BV84-1", "name": "Proline-rich protein 9", "aln": "MSFNDQQCKQPCVPPPCLQKTQEKCQAQAEDVCVSSCQDPCQDKCPQQAQEVCVSQCQELSQGNCPQQGQDPCLPPSQDQCLPQCAEPCQELAQTKCVEEFPQKVQEKCSSQSKGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T870-1", "uniprot_id": "PRR9_HUMAN", "id": "Q5T870-1", "name": "Proline-rich protein 9", "aln": "MSFSEQQCKQPCVPPPCLPKTQEQCQAKAEEVCLPTCQHPCQDKCLVQAQEVCLSQCQESSQEKCPQQGQEPYLPPCQDQCPPQCAEPCQELFQTKCVEVCPQKVQEKCSSPGKGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.:************* ****:***:**:**:.:**.****** ****.* .**** ** :******:* **.**** ****:***** ****** ***. ****: .***", "identical_positions": 84, "similar_positions": 18, "identity": "72.41%" }, { "cls_id": "homologset.agr.HGNC:32058", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLF0-1", "uniprot_id": "A0A8I6GLF0_RAT", "id": "A0A8I6GLF0-1", "name": "", "aln": "MVHFLHPLLWPRTLVLPYAQQDAQGHCLVQEEASPYPLVNICMDVLIAKLDKWCSKRPDGTLCLPEHWYFPHEIADKFLERMAWQGKLTDRTASIFQ-GKQVSLKLMNIRRVKLSAAAFTQAFCHHKLTEVDATSVDSQLLAPDIVHALQGSAWIQKNLQCLVLDSVSVP--QNSGLLALGQFTGLHTLSLANVSFRNEDLVGVSQLPSLESLDISNTLVTDISALLSCKNRLRSLTMHYLKCLAMNNPQILDVIRQLKCLLHLDISDHRQLKSDLAFYLLQQKDILPNLISLDISGGTDITDQVVESFLQHRPAMRFVGLLYTDAGYSDFFMGRQDLKVAGGANMSQISEALSRYRHRSCFVKEALYRLFTETLSLRVILPVVLKLVAIGMRNHPLDLPVQFTASACALNLTHQGLARGMPVRLLSEITYLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAARLVLRWVCKRESPKMQMMAVSITSILALKLSPEEIEQFQEELALAVKELLTIIRQKMAENLNDVTLLFTLKALWNLTDECPLACKYFIENEGLATIVQVLETF-SVSAIQSKVLGLLNNMAEVRELSPALVTEDLMEHTVSLLHSSDIEVSFLAAGVIAHLTC-DRQQWLSHSPRRRALLQDLHLTIQNWPSSRCDMSALVTYRSFKAFPPLLVNFSQPEVQRWALWAIHHVCNKNPSKYCKLLLEEGGLQLMYDIQEHDQASAQVRQMVSSILKEFRMHFTSFRRPPQPQRPF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BFL2-1", "uniprot_id": "ZY11A_MOUSE", "id": "A2BFL2-1", "name": "Protein zyg-11 homolog A", "aln": "---------------------------------------------------------------------------------MAWQGKLTDRTASIFQ-GKQMSLKLINIPRVKLSAAAFTKAFCHHKLIEVNATSVDSELLAPDIIHALQSSAWIQKNLQCLVLDSVSIP--PNSGLVALSHFTGLHTLSVANVSFCNEDLVSVSQLPNLGSLDISNTLVTNISALLSCKNRLRSLTMHYLKCLAMNSPQVLAVIRQLKCLLHLDISDHQQLRSDLAFYLLQQKDILPNLTSLDISGGTDVTDQAVESFLQHRPAMRFVGLLYTDAGYSDFFTAKQGLKVAGGANMSQISEALSRYRNRSCFVKEALFRLFTETLSLRAVLPVMLKLVAIGMRNHPLDLPVQFTASACALNLTRQELARGMPVRLLAEITDLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAAKLALRWVCRRESPKLRTMAVSITSILALKLSPEEMGQLQEELIMAIKELLTIIRQKLAENLDDVTFLFTLKALWNLTDECPLACKYFMENEGLATVIRVLETF-SISVIQSKVLGLLNNVAEVRELSSKLVTEDVIERIISLLHSSNLEVSFLAAGVLAHLTC-DRQHWLSRDLQRTDLLRYLHLAIQNWPSSRCDMSVLVTYRSFKAFSPLLVNFSQPEVQRWALWAIHHVCSKNP------------------------------------------------RPKDV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6WRX3-1", "uniprot_id": "ZY11A_HUMAN", "id": "Q6WRX3-1", "name": "Protein zyg-11 homolog A", "aln": "MVHFLHPGHTPRNIVPPDAQKDALGCCVVQEEASPYTLVNICLNVLIANLEKLCSERPDGTLCLPEHWSFPQEVAERFLRVMTWQGKLTDRTASIFR-GNQMKLKLVNIQKAKISTAAFIKAFCRHKLIELNATAVHADLPVPDIISGLCSNRWIQQNLQCLLLDSTSIP--QNSRLLFFSQLTGLRILSVFNVCFHTEDLANVSQLPRLESLDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQILAVIRELKCLLHLDISDHRQLKSDLAFHLLQQKDILPNVVSLDISGGNCITDEAVELFIRLRPAMQFVGLLATDAGSSDFFTTKQGLRVAGGASMSQISEALSRYRNRSCFVKEALHRLFTETFSMEVTMPAILKLVAIGMRNHPLDLRVQFTASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLLSLTNSRILVDVPFDRFDAAKFVMRWLCKHENPKMQTMAVSVTSILALQLSPEQTAQL-EELFMAVKELLAIVKQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLETF-SESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKHINSLLCSREMEVSYFAAGIIAHLTS-DRQLWISRDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQLWALWAMYHVCSKNPSKYCKMLVEEEGLQLLCDIQEHSEATPKAQQIAASILDDFRMHFMNYQRPTLCQMPF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TYQ1-1", "uniprot_id": "ZYG11_DANRE", "id": "Q5TYQ1-1", "name": "Protein zyg-11 homolog", "aln": "MIHLSQT----------------------MDKSSLPSLSDLCMSLVSSRLELFCEMRDDGSLSFREPLVFPQELADQLLCKMATDGVLNDSTVGIFRNCQQFRLRHACIRTARISAEAFHRALCPHRLVELDASRVNADLTIADILRGLSSNKSLQESLQRLVLNGLTMSSLEEPSRRCFSAMQGLRALSVSNVDFYDWGLADVCLLPRLESLDISNTSVSNLTPLLGLRSRLRYLTMHQLKRLEMTTAQLLAVLSQLEVLQHLDISDDKQFTSDVARQLLETPGILPQLVSLDVSGRKQVTDAAVKAFVEARPGMTFVGLLATDAGFSEFLSGEGSLKVTGEANETQICEALRRYSEREGFVREALFHLFSLTHAIEKPRPDILKLVALGMKNHPTTLNVQLAASACVFNLTKQELAFGIPVRLLGNVTQQLLEAMKTFPNHQQLQKNCLLSLCSDRILQEVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGAELFI-VKQLLHIVRQKTCQSTVDATLKFTLSALWNLTDESPTTCRHFIENQGLELFIKVLESFPSESSIQQKVLGLLNNIAEVSELHGELMVQSFLDHIRTLLHSPEVEVSYFAAGILAHLTSRGEKVWTLELTLRNTLLQQLHSAILKWPTPECEM---VAYRSFNPFFPLLECFQTPGVQLWAAWAMQHVCSKNAGRYCSMLLEEGGLQHLEAITSHPKTHSDVRRLTESILDGLQRHRARTGYTAIPKTQAHREKCNP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :* *.* *..**: :*. *: * .::*: ** :*:* *:* *::*: *.::* .**: .* .. :*:.** *:*:. ::. :. :. : **: **: ** * .*..*. ** * ******* *::::.** :.**: **** ** * *...*:* *: :*: * ******.:*: **:* **: .***:: ***:** . :** .*: *:. **.* ***** **** *:*: . .*:*:* *. :**.*** ** .*. **:***.:**: * ::. * :*****:**:*** * **::****.:***:* ** *:*****.::* *::* *.** :*********** ..*** :***:**:**::.::*:*.:*. ::: ***:: **** :**.*: *: ** : :*:** *::** :. *.*: ***.******* .* :*::*:**:** .::***:* * * **.********:*** ** *:.:..:.: :** * ::***::***::****. ..: * . * **: ** :* :**:. *.* *:****:.* *** *. * ** ** **: ***.**. . ", "identical_positions": 290, "similar_positions": 191, "identity": "37.56%" }, { "cls_id": "homologset.agr.HGNC:32060", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61830-1", "uniprot_id": "H3_YEAST", "id": "P61830-1", "name": "Histone H3", "aln": "MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5TEC6-1", "uniprot_id": "H37_HUMAN", "id": "Q5TEC6-1", "name": "Histone H3-7", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQEFKTDLRFQSSAVMALQEAREAYLVGLFEDTNLCAIHAKRVTIMPKDIQLVSRIRGERA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:********:**********:***********:**********************:***********: ****: *****.*******.********* ***:*. *:****:", "identical_positions": 118, "similar_positions": 13, "identity": "86.76%" }, { "cls_id": "homologset.agr.HGNC:32063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7V8-1", "uniprot_id": "D4A7V8_RAT", "id": "D4A7V8-1", "name": "", "aln": "MGVRGAFHLLLVCLSPALLSAVRINGDGQEVLFLAEGDNVRLGCPYILDPEDYGPNGLDIEWMQVNSEPS-HRENVFLTYQDKRISHGNLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMATRKVVVTVQARPAVPMCWTEGHMSKGNDVVLKCFANGGSQPLSYKWAKISGHSHPYRAGSYHSQHSFHSELSYQESFHSSINQGLSNGDLVLKGVNADDDGLYQCTVANHVGYSVCVVEVKVSDSQRVGMIVGAVLGSLLMLACLAVGIWGLICCCCGGAGAGGARGAFGYGVGGGVGGGACGDLASEIRVDAEAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKYAPPPCGGPEDVALVPRTTSAACEAGPSPVYIKVKSAEPADCADCAQVEQRSCKDGLLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P3A4-1", "uniprot_id": "VSIG8_MOUSE", "id": "Q6P3A4-1", "name": "V-set and immunoglobulin domain-containing protein 8", "aln": "MGVRGALHLLLVCLSPALLSAVRINGDGQEVMYLAEGDNVRLGCPYLLDPEDLGTNSLDIEWMQVNSEPS-HRENVFLTYQDKRIGHGNLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHMSKGNDVVLKCFANGGSQPLSYKWAKISGHSHPYRAGAYHSQHSFHSELSYQESFHSTINQGLGNGDLLLKGINADDDGLYQCTVANHVGYSVCVVEVKVSDSQRVGMIVGAVLGSLLMLACLALGIWGLICCCCGGGGAGGARGAFGYGVGGGVGGGACGDLASEIRVDAEAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKYAPPPCGGPEDVALVPRTASASCEAGPSPVYIKVKSAEPADCADCAQVEQRSCKDGLLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DPA2-1", "uniprot_id": "VSIG8_HUMAN", "id": "P0DPA2-1", "name": "V-set and immunoglobulin domain-containing protein 8", "aln": "MRVGGAFHLLLVCLSPALLSAVRINGDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGGSGAGGARGAFGYGNGGGVGGGACGDLASEIREDAVAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKYAPPPCGGPEDVALAPCTAAAACEAGPSPVYVKVKSAEPADCAEG----PVQCKNGLLV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * **:************************::*************:***** *.*.**********:*: *******:******.**.*************************************************:******************: ********:*.**************** :*****:* ****:************:*****.****:**.:. ***********:***************:*:*:*:* ****** *.***:*****:******.************ ***************** ** *********************************************.* *::*:*********:***********: .**:****", "identical_positions": 355, "similar_positions": 41, "identity": "84.93%" }, { "cls_id": "homologset.agr.HGNC:32068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TGZ0-1", "uniprot_id": "MIC10_HUMAN", "id": "Q5TGZ0-1", "name": "MICOS complex subunit MIC10", "aln": "MSESE------------------------LGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAPYLLHGKYVKEQEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TNS2-1", "uniprot_id": "MIC10_MOUSE", "id": "Q7TNS2-1", "name": "MICOS complex subunit Mic10", "aln": "MSESE------------------------LGRKWDRCMADTVVKLGTGFGLGIVFSLTFFKRRMWPLAFGSGVGLGMAYSNCQHDFQAPYLLHGKYVKEQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYW8-1", "uniprot_id": "MIC10_RAT", "id": "B2RYW8-1", "name": "MICOS complex subunit Mic10", "aln": "MSESE------------------------PGRKWDRCMADALVKLGTGFGLGMVFSLTFFKRRKWPLAFGSGVGLGMAYSNCQHDFQAPYLLHGKYVKEQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96VH5-1", "uniprot_id": "MIC10_YEAST", "id": "Q96VH5-1", "name": "MICOS complex subunit MIC10", "aln": "MSEQAQTQQPAKSTPSKDSNKNGSSVSTILDTKWDIVLSNMLVKTAMGFGVGVFTSVLFFKRRAFPVWLGIGFGVGRGYAEGDAIFRSSAGLRSSKV-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VY65-1", "uniprot_id": "Q9VY65_DROME", "id": "Q9VY65-1", "name": "MICOS complex subunit MIC10", "aln": "MSTTPEDR--------LRENIN-------------RCLSDSLVKGVGGLVIGSVVTLLFFRRRIWPVWLGTGFGVGVAYRGCEKELNDVKFGQRK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1B2-1", "uniprot_id": "Q9W1B2_DROME", "id": "Q9W1B2-1", "name": "MICOS complex subunit MIC10", "aln": "MSHEPQKP--------AKSAVKEPPVVSEETRTTDKCLADFCLKGGSGLIIGSAVTLFFTRPQTYPIWLGLGVGMGVAYDCCQARWN-----QQ--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ::: :* *: :* :: * : : :*: :* *.*:* .* : . : ", "identical_positions": 12, "similar_positions": 19, "identity": "11.76%" }, { "cls_id": "homologset.agr.HGNC:32069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A460-1", "uniprot_id": "D4A460_RAT", "id": "D4A460-1", "name": "", "aln": "MSVGAMN-KICP-------QADAESNMTTGRKTRPGGE-GCGPLCYSRRGACLSVFLLLLLAMLAALLLIVTILGHPQRTPEPHSCVTLANRTGFLCHDRRYCIPAHAVCDGIRTCPHGEDEAENLCRDLPKSLPSFLLTTCGNPDSWIYSDQKCDGTNNCGDCSDELSPVTACPPCGPGWWYCTPTVFRYCSCVPRVLCRDGVQHCSDWSDEYSCPGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YYZ1-1", "uniprot_id": "D3YYZ1_MOUSE", "id": "D3YYZ1-1", "name": "", "aln": "MSVGCERAEFCPACFWFLGQADAESNITTRRKARPGDE-GCGPLCCSRRGACLSVGLLLLLAMLAALLAVATILGHPPRTPETHSCVTLANRTGFLCHDRRHCIPAHAVCDGIRTCPHGEDEAESLCRDVPQSLPSFLLTTCGDPDSWIYSDQKCDGVNNCGDCSDELSPVTTCPPCGPGWWRCSPTVFKYCSCVPRDLCRDSVQHCSDWSDEYSCPGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T700-1", "uniprot_id": "LRAD1_HUMAN", "id": "Q5T700-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 1", "aln": "-----MN-KVFP--------QGENGYTAAESKAHPGGEAGGGHLCCSRRGACLSASLLLLLATVAALIALVTILGLPSCTPGAQACITLTNRTGFLCHDQRSCIPASGVCDGVRTCTHGEDEDESLCRDVPQSLPHFLVAHCGDPASWIYSDQKCDGTNNCGDCSDELSPVTVCPPCGPGWWRCPSTFFKYCDCIPRHLCRDHVQHCSDWSDEYACPGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. * . :. :: *::**.* * * ** ********. ****** :***: :.**** * ** .::*:**:*********:* **** .****:***.***** *.****:*:*** **:: **:* ***********.**************.********* *..*.*:**.*:** **** ***********:****", "identical_positions": 137, "similar_positions": 40, "identity": "62.56%" }, { "cls_id": "homologset.agr.HGNC:32070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0E3-1", "uniprot_id": "LYSM1_MOUSE", "id": "Q9D0E3-1", "name": "LysM and putative peptidoglycan-binding domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------MASPSRQPPLGGSGLLHGSRARSYGSLVQSSCSPVRERRLEHQLEPGDTLAGLALKYGVTMEQIKRTNRLYTNDSIFLKKTLYIPILSEPRDLFNGLDSEEE-NDGEEEVRPSKDEIGSSSGRRKNRGSGSGRPNGTGLP-PHQETSTPSHDLSASDFLKKLDSQISLSKKAAAQKLRKGESGVPEEDTGLYPSSPRMQQRAVLGPVPLTRTSRTQTLRDQEDEIFKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPY6-1", "uniprot_id": "A0ABK0LPY6_RAT", "id": "A0ABK0LPY6-1", "name": "LysM and putative peptidoglycan-binding domain-containing protein 1", "aln": "MLFHACIAQAGRPASSALRGSVFPMILPGRCAFWEMKSFGYLFYFLIFLERTPLTWTQVLASRRIQVFGDPRSFVTLDLGSEEMASPSRQPPLGGSGLLRGSRARSYGSLVQSSCSPVRERRLEHQLEPGDTLAGLALKYGVTMEQIKRTNRLYTNDSIFLKKTLYIPILTEPRDLFNGLDSEEEENDGEEEVRPSKDEIGSSSGKRKNQGSASSQPKGTGLP-PHQGTSTPSHDLSASDFLKKLDSQISLSKKAAAQKLRKGESGVPEEDTGLYPSSPRMQQRAVLGPVPLTRTSRTQTLRDQEDEIFKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96S90-1", "uniprot_id": "LYSM1_HUMAN", "id": "Q96S90-1", "name": "LysM and putative peptidoglycan-binding domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------MASPSRQPPPGGSGLLQGSRARSYGSLVQSACSPVRERRLEHQLEPGDTLAGLALKYGVTMEQIKRANRLYTNDSIFLKKTLYIPILTEPRDLFNGLDSEEE-KDGEEKVHPSNSEVWPHSTERKKQETGAGRANGEVLPTPGQETPTPIHDLSASDFLKKLDSQISLSKKAAAQKLKKGENGVPGEDAGLHLSSPWMQQRAVLGPVPLTRTSRTRTLRDQEDEIFKL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********* ******:*************:***********************************:********************:************** :****:*:**:.*: . * .**:: :.:.:.:* ** * * *.** ***************************:***.*** **:**: *** ******************:************", "identical_positions": 186, "similar_positions": 27, "identity": "59.81%" }, { "cls_id": "homologset.agr.HGNC:32071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A5F8MPH1-1", "uniprot_id": "A0A5F8MPH1_MOUSE", "id": "A0A5F8MPH1-1", "name": "", "aln": "---MAFLWQLPQRLLLLGTTALTVSALGTADLTDLCGQTWQEDALQLRSHSASRKFYFVTPDTDCILWLRAAAPEDRMRFQFRFFLVYSLSSAIRITAATQA-------------TAATPTTKASSRDPCAPGSYLQFYDGPQEAPRALGPPICGLTIPAPFTSSGPWLGLRLVTRGRQPRVDFLGEVTSFHLGS----CG--TYFRCRNGRCVPRSLLCDD-WNMDNCGDGSDQDSRPPASCGGPSLVPKEMGTLEDN---SSKALTLLVAPGSTAERTPPEGLAPITQEVLEGPWLWWVALASSMLLTCTGLLWCCCCPGWLAWHPGAHRLRLRCCAACNVCHLCPGRVAPGGLWLSWPAFQNQGGHR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2E6-1", "uniprot_id": "D4A2E6_RAT", "id": "D4A2E6-1", "name": "", "aln": "---MAFLRLLPQRLLLLGTTALTVSALGTADLTDLCGQTWQGDGLQLRSHSTSRKFYFVTPDTDCTLWLRAAAPEDRMRFQFRFFLVYSLSSATRTTAATQT-------------TVATPTAKASSRDPCAPGSYLQFYDGPQEAPRALGPPICGLTIPAPFMSSGPWLGLRLVTRGRQPRVDFLGEVTSFRLGP----CG--IYFRCRNGRCVPWSLLCDN-WNMDNCGDGSDQDSRPPASCGGPSLMPKETTTMEND---SSKPLTLLVALGSAAKQTSPAGLAPVTQEVLEGPWLWWVALASSILLTCTGLLWCCCCLGWLAWHPDAHRLRLRCCAACNVCHQCPGRVAPGGLWLSWPAFQNQGDHR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SZI1-1", "uniprot_id": "LRAD2_HUMAN", "id": "Q5SZI1-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 2", "aln": "-MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAPDTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAP----------------------PALNTSSPAPADPCAPGSYLQFYEGPPGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGP----CG--AYFRCQNGRCIPSSLVCDP-WGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAH---TSRSLTPSPALGSAGS--------------------LWIAAE---------------------------------------------RSSPAGRDPTRQDAALEGSTE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5D8-1", "uniprot_id": "A0ACD6B5D8_DANRE", "id": "A0ACD6B5D8-1", "name": "", "aln": "MAAARCIQQLSGWFVLLSLMTRQSHSIETVNVVDFCGQTIQGDGMIVKSHQESRKYYFVSMGTDCHLTMQSATPRDKVQFYFRFFLVYSLLRVSPHSPAPLPESPKGSSASGLTRPDLEPTTEEGPEDPCHAGSYIQFYDGRDRSAPLIGPPLCGKSPPRPVLSTGKFLTLRLVTRGTQPRVDFVGDFTSFRLGFNQSECSGEPYFNCRNGKCIPKSLVCADDKGIDNCGDGSDLIDYPGCNAPQSTPNPPQRHATQPAPMLNVPTLTVSTLKNCATPKAIPDPDSVTDSQSSMSLLALYVVLG--VTAAGVLLCWCCWAPGWFLWRVSVFRFMPCCNSCCASCQFCG-RSCSQNKDHRLAKVTPEGAATPVSSTTTVAV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. ::**. : :: *.::.::**** * *.: ::** **::***: .*** * :::*:* *:::* ********* . *:. .. *** .***:***:* :. :*.*:** . * *. *:* :* ******* ******:*:.***:** *. **.*:**:*:* **:* .:******** . . ... .: * : : : . .** ..: ::. * .. . :* ", "identical_positions": 97, "similar_positions": 80, "identity": "25.53%" }, { "cls_id": "homologset.agr.HGNC:3208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70251-1", "uniprot_id": "EF1B_MOUSE", "id": "O70251-1", "name": "Elongation factor 1-beta", "aln": "MGFGDLKTPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSGPPPADLCHALRWYNHIKSYEK-EKASLPGVKKSLGKYGPSSVEDTTGSGAADAKDDDDIDLFGSDDEEESEEAKKLREERLAQYESKKAKKPAV-VAKSSILLDVKPWDDETDMTKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6IPG1-1", "uniprot_id": "EF1B_RAT", "id": "A6IPG1-1", "name": "Elongation factor 1-beta", "aln": "MGFGDLKTPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAISGPPPADLCHALRWYNHIKSYEK-EKASLPGVKKSLGKYGPVSVADTTGSGAADAKDDDDIDLFGSDDEEESEDAKRLREERLAQYESKKAKKPAV-VAKSSILLDVKPWDDETDMTKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24534-1", "uniprot_id": "EF1B_HUMAN", "id": "P24534-1", "name": "Elongation factor 1-beta", "aln": "MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEK-EKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPAL-VAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96827-1", "uniprot_id": "EF1B_DROME", "id": "O96827-1", "name": "Probable elongation factor 1-beta", "aln": "MAFGDVTTPQGLKELNAFLADNSYISGYTPSKADLSVFDALGKAPSADNVNVARWYRHIASFEAAERAAWSGTPLPQLAGGKPTVAAAAKP-AAD--DDDDVDLFGSDDEED-EEAERIKQERVAAYAAKKSKKPAL-IAKSSVLLDVKPWDDETDMKEMENNVRTIEMDGLLWGASKLVPVGYGINKLQIMCVIEDDKVSIDLLQEKIEEFEDFVQSVDIAAFNKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32471-1", "uniprot_id": "EF1B_YEAST", "id": "P32471-1", "name": "Elongation factor 1-beta", "aln": "MASTDFSKIETLKQLNASLADKSYIEGTAVSQADVTVFKAFQSAYP----EFSRWFNHIASKAD-EFDSFP----------------AASAAAAEEEEDDDVDLFGSDDEEADAEAEKLKAERIAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIPIGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQSTDIAAMQKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *... *: ** ***:***.* . *:**::**.*. . . . **:.** * * : . :: . *:: :***:********* :*:::: **:* * :**: *** *** : **********:: :: *::*: :** **: :::*:*:**:**** **:*****. * *::.* **.*** *:**::*:", "identical_positions": 93, "similar_positions": 61, "identity": "40.97%" }, { "cls_id": "homologset.agr.HGNC:321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEH9-1", "uniprot_id": "D4AEH9_RAT", "id": "D4AEH9-1", "name": "Glycogen debranching enzyme", "aln": "------------------------------------------------------------------------------------------MEHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAVTVYTNYPFPGEAFNREKFRSLDWEN-----------PTEREDDSDKYCKVHLQQSGSFQYYFLQG-QEKSGGG------YIVVDPILRVG--ADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQALGLSRSCYSLADQLELNPDFSRP-NRRYTWDDVGQLVEKLKREWNILCITDVVYNHTAANSKWIHEHPESAYNLVNSPHLKPAWVLDRALWHLSCDVADGKYREKGVPALIENDHHMNCIRKIIWEDIFPRIQLWEFFQVDVQKAVEQFRRLLSQ-ENRRVTKSEPK--------EHLKIIQD----PEFRRLGCAVDMNIALATFIPHD----NGPAA-IEECCNWFRKRLEELNSEKHHLTSCHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKYPLVTRYFTFPFEEMALSAEESLLHRPDKACFLMAHNGWVMG-DDPLRNFAE--PG-SNVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATHFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEDLDNIFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCL----------------------------------RPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTVVSMACCASGSTRGYDELVPHQISVVAEERFYTKWNPGASPSDTGDVSIHSGIIAARCAINRLHQELGAKGF----IQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERN------TKPYRKDENSINGMPNMTVELR-ERIQLHESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSSHFKSGSLAVDNSDPILKIPFASIASKLTLAELNQVLYRCESEEQ---EDGGGCYDIPNWSSLKYAGLQGLMSVLAEIRPKNDLGHPFCENLRSGDWMIDYVSGRLISR--SGSIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDVAWKQMSSFVQNGSTFVKHLSLGSVQMCGVGKCPCLPLLSPSLLDVPCRLNEITKEKEQCCASLAAGLPHFSSGLFRCWGRDTFIALRGMLLVTGRYLEARNIILAFACTLRHGLIPNLLGEGTYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDS--APLPAGTL--DQPLFEVIQEAMQRHMQGIQFRERNAGPQIDRNMKDEGFNITVGVDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLCKSAVRWLLELSKKNIFPYHEVRVRR-HGKVVAVSYDEWNRKIQNSFEKLFHVSEDPSDPNEKHPNL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTAEKAWKALEIAEGKLLGPLGMKTLDPDDMVYCGVYDNALDNDNYNLARGFNYHQGPEWLWPIGYFLRAKLYFSKMMGPETAAKT--------VFLVKNVLSRHYVHLERSPWKGLPELTNENGQYCPFSCETQAWSMAAVLETLYDL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPN4-1", "uniprot_id": "F8VPN4_MOUSE", "id": "F8VPN4-1", "name": "Glycogen debranching enzyme", "aln": "------------------------------------------------------------------------------------------MEHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAVTVYTNYPLPGEAFNREKFRSLDWEN-----------PTEREDDSDKYCKLHLQQSGSFQYYFLQG-NEKSGGG------YIVVDPILRIG--VDNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLSRSCYSLADQLELNPDFSRP-SKRYTWSDVGQLVEKLKREWNILCITDVVYNHTATNSKWILEHPESAYNLVNSPHLKPAWVLDRALWHFSCDVADGKYREKGVPALIENDQHMNCIRKIIWEDIFPRIQLWEFFQVDVHKAVEQFRRLLSQ-ENRRVTKSEPK--------EHLKIIQD----PEYRRRGCAVDMDTALATFIPHD----NGPAA-IEECCNWFRKRLEELNSEKHHLTSCHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKYPLVTRYFTFPFGEMALSAEEALIHLPDKACFLMAHNGWVMG-DDPLRNFAE--PG-SDVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATHFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEELDNIFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCL----------------------------------RPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTVVSMACCASGSTRGYDELVPHQISVVAEERFYTKWNPGASPADTGDVNVHSGIIAARCAINRLHQELGAKGF----IQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERN------TKPYKKDENSINGMPNMTVELR-EHIQLHESKIVRQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSSHFKSGSLAVDNADPILKIPFASIASKLTLAELNQVLYRCESEEQ---EDGGGCYDIPNWSSLKYAGLQGLMSVLAEIRPKNDLGHPFCENLRSGDWMIDYVSGRLISR--SGSIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDVAWKQMSSFVQNGSTFVKHLSLGSVQMCGVGKCPCLPLLSPSLLDVPCRLNEITKEKEQCCASLAAGLPHFSSGLFRCWGRDTFIALRGMLLVTGRYLEARNIILAFASTLRHGLIPNLLGEGTYARYNCRDAVWWWLQCIQDYCRTVPNGLDILKCPVSRMYPTDDS--APLPAGTL--DQPLFEVIQEAMQRHMQGIQFRERNAGPQIDRNMKDEGFNITAGIDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLCKSAVRWLLELSKKNIFPYHEVRVKR-HGKVVAVSYDEWNRKIQNNFEKLFHVSEDPSDPNEKHPNL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTAEKAWKALEIAEKKLLGPLGMKTLDPDDMVYCGVYDNALDNDNYNLARGFNYHQGPEWLWPIGYFLRAKLYFSKMMGPETAAKT--------VFLVKNVLSRHYVHLERSPWKGLPELTNENGQYCPFSCETQAWSMAVVLETLYDL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35573-1", "uniprot_id": "GDE_HUMAN", "id": "P35573-1", "name": "Glycogen debranching enzyme", "aln": "------------------------------------------------------------------------------------------MGHSKQIRILLLNEMEKLEKTLFRLEQGYELQFRLGPTLQGKAVTVYTNYPFPGETFNREKFRSLDWEN-----------PTEREDDSDKYCKLNLQQSGSFQYYFLQG-NEKSGGG------YIVVDPILRVG--ADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLSRSCYSLANQLELNPDFSRP-NRKYTWNDVGQLVEKLKKEWNVICITDVVYNHTAANSKWIQEHPECAYNLVNSPHLKPAWVLDRALWRFSCDVAEGKYKEKGIPALIENDHHMNSIRKIIWEDIFPKLKLWEFFQVDVNKAVEQFRRLLTQ-ENRRVTKSDPN--------QHLTIIQD----PEYRRFGCTVDMNIALTTFIPHD----KGPAA-IEECCNWFHKRMEELNSEKHRLINYHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKHPLVTRYFTFPFEEIDFSMEESMIHLPNKACFLMAHNGWVMG-DDPLRNFAE--PG-SEVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATYFQGVRLDNCHSTPLHVAEYMLDAARNLQPNLYVVAELFTGSEDLDNVFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCL----------------------------------RPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTIVSMACCASGSTRGYDELVPHQISVVSEERFYTKWNPEALPSNTGEVNFQSGIIAARCAISKLHQELGAKGF----IQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERN------TKPYRKDENSINGTPDITVEIR-EHIQLNESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSPHFKSGSLAVDNADPILKIPFASLASRLTLAELNQILYRCESEEK---EDGGGCYDIPNWSALKYAGLQGLMSVLAEIRPKNDLGHPFCNNLRSGDWMIDYVSNRLISR--SGTIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDTAWKQMSSFVQNGSTFVKHLSLGSVQLCGVGKFPSLPILSPALMDVPYRLNEITKEKEQCCVSLAAGLPHFSSGIFRCWGRDTFIALRGILLITGRYVEARNIILAFAGTLRHGLIPNLLGEGIYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDS--APLPAGTL--DQPLFEVIQEAMQKHMQGIQFRERNAGPQIDRNMKDEGFNITAGVDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLSKSAVRWLLELSKKNIFPYHEVTVKR-HGKAIKVSYDEWNRKIQDNFEKLFHVSEDPSDLNEKHPNL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTTEKAWKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDNYNLAKGFNYHQGPEWLWPIGYFLRAKLYFSRLMGPETTAKT--------IVLVKNVLSRHYVHLERSPWKGLPELTNENAQYCPFSCETQAWSIATILETLYDL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAR0-1", "uniprot_id": "A0A8M2BAR0_DANRE", "id": "A0A8M2BAR0-1", "name": "Glycogen debranching enzyme", "aln": "-------------------------------------------------------------------------------------------MTAKQTRVMVLNDMEKLDRTLFRLDQGFELQFRLGPTLQGKHVRVYTNYPTEGERFDRQKFHALDWIN-----------PTAREDDSDKFCTLDLKISGSYQYYFGHGGDEKSGGG------YIVVDPVLRVG--ADNHVLPLDCITIQTYLSKCLGPLDEWSDRLRVAKEAGYNMIHFTPLQTLGESRSCYSLADQLELNPDFSPS-GQTYTWTDAGNLVEKLKNEWNMLCITDVVYNHTASNSKWIKKHPECGYNLVNSPHLKPAWVLDRALWHVTCAIADGKYEDRGLPALIQDHPHLHAIRGVLWQEVFPKIKLWEFFQVKIEALVEQFRALLQSGAKPDSSKTDGK--------KQLKIIQD----PQYRRFGNTVDMNTALELFVPNG----NSPGA-IEDCCNWLRRKLEELNGEQFHEVKHHQEQATNCIDGTVSYERLADHGPKLGPITRKHPLVTRYFTFPFEETTLEQDLELINQPEKSCHFLAHNGWVMG-DDPLRNFAE--PG-SNVYIRRELICWGDSVKLRYGSGPEDCPYLWAHMQKYTEITAKHFVGVRLDNCHSTPLHVAEAMLAAARSVRPNLYVIAELFTGSELIDNVFVNRLGITSLIREAMSAGDSHEEGRLVYRYGGEPVGAFLQPSL----------------------------------RPLVPSIAHAMFLDVTHDNECPIQIRSVYDSLPSSAIVSMACCATGSTRGYDELVPHQISVVSEERFYTKWSSQAKPSSPNEVNLQTGIIAGKLALNRLHQELAAKGF----SQVFVDQVDEDIVAVTRHCPSTHQSVVAVCRTAFKNPKHHRYTDEVPPMCIPGKIEEVVLEARTVERQ------TGTYKKDERSINGMPEYTVEIK-EHIQLADSKVVRQAGVTSRGRSEYVQEIVFEKLTPGSVIAFRVSLDPKSQELVGVLRNHLIQFNPLYKAGSVPDSNTPDILKSPLTQIMSKLTLADMNLLLFRCDSEEK---EDGGGCYNIPGWTPLKYGGLQGLLSVMAEIRPKNDLGHPFCDNLRQGDWMIDYVSNRLVSR--GGPLAEVGQWFQAMFAYLKHIPRYLIPCYFDAILVGAFTTALDATFRQMSSFVQDGSSFVKLLALGSVQMCGVGRFPALPPLSPALSDVPYRVNEITKEKEQCCVSMAAGLPHFSAGIFRCWGRDTFIALRGLLLVTGRHLEARNIILAFAGTLRHGLIPNLLGEGVGARFNCRDAVWWWLQCIQDYCTMVPNGTDILQCPVSRMYPTDDS--KPLTAGTV--DQLLYEVIHEAMERHIQGIEFRESNAGPQIDRNMRDEGFNIEAKVNPDTGFVYGGNRFNCGTWMDKMGESERARNKGIPATPRDGSAVEIVGLCKSTLRWLVELHKKGLFPYNTVKIQR-DGKQLSVAYDEWEMKIQKNFEKMFYVSHDPNDPNEKHPEL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTVEHAWKALNMAEEKLLGPLGMKTLDPDDMVYCGVYDNSLDNDNYNLAKGFNYHQGPEWLWPIGYFLRAKIFFAKKMGKDTYDKT--------VYLVKNVLSRHNVHMERSSWKGLPELTNENGQYCSFSCETQAWSLAAVLEVLHDL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32THB4-1", "uniprot_id": "A0AB32THB4_DANRE", "id": "A0AB32THB4-1", "name": "Glycogen debranching enzyme", "aln": "-------------------------------------------------MRSLSDVAARTAGDPDATFPVFKGHPKKST---------ASMFRGKQTRVLLLNDMESMERTLFRLEQGFELQFRLGPTLQGKSVHVHTNYPALYKKFVASSFRQLEWEN-----------PSGREDDSDKYCKLDLEIAGSYQYYFGCGNEQKTGGG------YIIVDPVLRVG--HERKILPLDCITVQTYLAKCLGPLDEWLDRLKVARETGYNMIHFTPLQKLGMSKSCYSIADQLELNPDFSPP-GKNYTWMDVGNLTEKLKKEWNMICITDVVYNHTAANSKWIRLHPECGYNLVNSPHLKPAWLLDRALWHFSCAIADGKYSDGGLPPLIENEKHITILKGLLWTEVFTHLKLWEFLQVNVEKAVEQFRKVLQAGNKPVGPELEGK--------PKLKVIQD----SQFRRLSNTVDMQLALEMFGRHT----NGPKS-IEECCDWFKKSLEELNVECYKEMHSHHEKAIDCIVGTVCYERIAAHGPQLGPVTQTNPLVLRYFTFPFEDMTMEQESQLMQDPNNACHLLAHNGWVMG-DDPLRNFAE--AG-STVYLRRELVCWGDSVKLRYGDKPEDCPYLWAHMKKYTEITAKHFSGVRLDNCHSTPLHVAEYILAVARQHRPDLYVVAELFTGSEELDNVFMTRLGITSLIREAMSAGDSHEEGRLVYRFGGEPVGSFIQPNL----------------------------------RPLEPSIAHAMFLDVTHDNECPIQVRSAYDALPSSAIVSMACCASGSTRGYDELVPHQISVVKEERLYPKWNPDALPSSGREVNLHSGITAGKLALNKLHQELAENGF----TQVYVDQLDEDTVAVTRHCPSTHQSVVTVCRTAFKDPKTHQFRESLAPMYIPGKIEEVILEARTVERS------AESYVKDETFINGLPNYTVEIR-EHIQLKESQIVKQGDATTKGRSEFVEEILFEKLTPGSVIAFRVSLDPNSQKMVGYLRTQLSQFNRLFKSGSLTDSNVAGILKISLEFLISKLTLAELNVLLFRCDAEEQ---EDGGGCYNIPSWMPLKYGGLQGFVSVLSEIRPKNDLGHPFCDNLRQGNWILDYVSTRLINK--GGALREVGKWFKAVFSYLKHLPRYLVPCYFDAIIVGAYATAVDAVFNQMSSFVLNGSTLVKQLALGSVQMCGVGRVPALPHLSPELEDVPVRVNSATKQEEQCCVSIAAGLPHFSTGIFRCWGRDTFIALRGLMLLTGRHLEARDIILAFAGTMRHGLIPNLLGQGVAARYNCRDAVWWWLQCIQDYCTIVPSGTDILMCPVSRMYPTDDS--EAQALGTVAHDQPLYVLIQEAMQRHMQGIQFRERNAGPQIDWNMQHEGFNVEAKVNPETGFVYGGNGFNCGTWMDKMGESDKAHNKGVPATPRDGSAVEIVGLSKSAVRWLMMMNETGHFPYSSVKIHR-DGAEQLITYKEWNQRIQENFERFFYVSDDPADPNEQRPDL---VHKKCIYKDSHGASSPWCDYQLRPNFTIAMVVAPELFSVQRAWKALEIVETKLLGPLGMKTLDPDDLVYCGVYDNALDNDDYNRAKGFNYHQGPEWIWLVGYFLRAKLYFGRKMGQEKYNQS--------VYLVKNVLSRLHTHLERSPWKGLPELTNENGQYCPFSCETQAWSIATVLEALFDL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2H8-1", "uniprot_id": "Q9W2H8_DROME", "id": "Q9W2H8-1", "name": "Glycogen debranching enzyme", "aln": "MRYQLFRWLYGLIATVDNEPLPLQIKSEEEAFGENKKKKQLASLENAISPGKLDSVAIRTVPSANANAMGNAGSAEIVSNQIIRRREMSTMGKETESHSIPISEGQDAEHILYRLKRGSKLSVHPDASLLGRKIVLYTNYPAEGQKFVRTEYRVLGWQLSNGKQITSVMHPEAHVVDTDIRSQVELNMSGTYHFYFRYLERPDTGCSGADGALYVQVEPTLHVGPPGAQKTIPLDSVRCQTVLAKLLGPLDTWEPKLRVAKEAGYNVIHFTPIQELGGSRSCYSLRDQLKVNSHFAPQKGGKISFEDVEKVIKKCRQEWGVASICDIVLNHTANESDWLLQHPDATYSCATCPYLRPAFLLDATFAQCGADIAEGSLEHVGVPAVIEQECHLEALKYQLHTSYMSKVNIHELYQCDVMKYVNEFMSQVRTREPPKNVANECRF-------QEIQLIQD----PQYRRLASTINFELALEIFNAFHGDCFDEESR-FRKCAETLRRHLDALNDRVRCEVQGYINYAIDNVLAGVRYERVQGDGPRVKEISEKHSVFMVYFTHTGTQGKSLTEIEADMYTKAGEFFMAHNGWVMGYSDPLRDFAEEQPGRANVYLKRELISWGDSVKLRFGRRPEDSPYLWQHMTEYVQTTARIFDGVRLDNCHSTPLHVAEYLLDAARKINPELYVVAELFTNSDYTDNVFVNRLGITSLIREALSAWDSHEQGRLVYRYGGVPVGGFQANSS----------------------------------RHEATSVAHALFLDLTHDNPSPVEKRSVYDLLPSAALVSMACCATGSNRGYDELVPHHIHVVDEERTYQEWG--------KGVDSKSGIMGAKRALNLLHGQLAEEGF----SQVYVDQMDPNVVAVTRHSPITHQSVILVAHTAFGYPSPNAGPTGIRPLRFEGVLDEIILEASLTMQSDKPFDRPAPFKKDPNVINGFTQFQLNLQ-EHIPLAKS-TVFQTQAYSDGNN---TELNFANLRPGTVVAIRVSMHPGPRTSF----DKLQKISAALRIGSGEEYS-------QLQAIVSKLDLVALSGALFSCDDEERDL-GKGGTAYDIPNFGKIVYCGLQGFISLLTEISPKNDLGHPLCNNLRDGNWMMDYISDRLTS---YEDLKPLSAWFKATFEPLKNIPRYLIPCYFDAIVSGVYNVLINQVNELMPDFIKNGHSFPQSLALSTLQFLSVCKSANLPGFSPALSPP---------KPPKQCVTLSAGLPHFSTGYMRCWGRDTFIALRGSMFLTGRYNEARFIIIGFGQTLRHGLIPNLLDSGSKPRFNCRDAIWWWMYCIKQYVEDAPKGAEILKDKVSRIFPYDDA--DAHAPGAF--DQLLFDVMQEALQVHFQGLQYRERNAGYEIDAHMVDQGFNNQIGIHPETGFVFGGNNFNCGTWMDKMGSSQKAGNKGRPSTPRDGSAVELVGLQYAVLRFMQSLAEKEVIPYTGVERKGPSGEVTKWSYKEWADRIKNNFDKYFFVSES------ETCSV---ANKKLIYKDSYGATQSWTDYQLRCNFPITLTVAPDLCNPQNAWRALERAKKYLLGPLGMKTMDPEDWNYRANYDNSNDSTDCTVAHGANYHQGPEWVWPIGFYLRARLIFAKKCG--HLDET--------IAETWAILRAHLRELQTSHWRGLPELTNDNGSYCGDSCRTQAWSVAAILEVLYDLHSLGADVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06625-1", "uniprot_id": "GDE_YEAST", "id": "Q06625-1", "name": "Glycogen debranching enzyme", "aln": "---------------------------------------------------MNRSLLLRLSDTGEPITSCSYG------------------KGVLTLPPIPLPKDAPKDQPLYTVK----LLVSAGSPVARDGLVWTNCPPDHNTPFKRDKFYKKIIHS---------------SFHEDDCIDLNVYAPGSYCFYLSFRNDNEKLETTR--KYYFVALPMLYIN----DQFLPLNSIALQSVVSKWLG--SDWEPILSKIAAKNYNMVHFTPLQERGESNSPYSIYDQLQFDQEHFKS------PEDVKNLVEHIHRDLNMLSLTDIVFNHTANNSPWLVEHPEAGYNHITAPHLISAIELDQELLNFSRNLKS-----WGYPTELKNIEDLFKIMDGIKVHVLGSLKLWEYYAVNVQTALRDIKAHWNDESNESYSFPENIKDISSDFVKLASFVKDNVTEPNFGTLGERNSNRINVPKFIQLLKLINDGGSDDSESSLATAQNILNEVNLPLYREYDDDVSEILEQLFNRIKYLRLDDGGPKQGPVTVDVPLTEPYFTR-------------FKGKDGTDYALANNGWIWN-GNPLVDFAS---QNSRAYLRREVIVWGDCVKLRYGKSPEDSPYLWERMSKYIEMNAKIFDGFRIDNCHSTPIHVGEYFLDLARKYNPNLYVVAELFSGSETLDCLFVERLGISSLIREAMQAWSEEELSRLVHKHGGRPIGSYKFVPMDDFSYPADINLNEEHCFNDSNDNSIRCVSEIMIPKILTATPPHALFMDCTHDNETPFEKRTVEDTLPNAALVALCSSAIGSVYGYDEIFPHLLNLVTEKRHYDISTP--------TGSPSIGITKVKATLNSIRTSIGEKAYDIEDSEMHVHHQG-QYITFHRMDVKSGKGWYLIARMKFSD--NDDPNETLPPVVLNQSTCSLRFSYALERVG-------DEIPNDDKFIKGIPTKLKELEGFDISYDDSKKISTIKLPN-------------EFPQGSIAIFETQQN-----------GVDESLDHFIRSGALKATS--------------SLTLESINSVLYRSEPEEYDVSAGEGGAYIIPNFGKPVYCGLQGWVSVLRKIVFYNDLAHPLSANLRNGHWALDYTISRLNYYSDEAGINEVQNWLRSRFDRVKKLPSYLVPSYFALIIGILYGCCRLKAIQLMSRNIGKSTLFVQSLSMTSIQMVSRMKSTSILPG-------------------ENVPSMAAGLPHFSVNYMRCWGRDVFISLRGMLLTTGRFDEAKAHILAFAKTLKHGLIPNLLDAGRNPRYNARDAAWFFLQAVQDYVYIVPDGEKILQEQVTRRFPLDDTYIPVDDPRAFSYSSTLEEIIYEILSRHAKGIKFREANAGPNLDRVMTDKGFNVEIHVDWSTGLIHGGSQYNCGTWMDKMGESEKAGSVGIPGTPRDGAAIEINGLLKSALRFVIELKNKGLFKFSDVETQD----GGRIDFTEWNQLLQDNFEKRYYVPEDPSQDADYDVSAKLGVNRRGIYRDLYKSGKPYEDYQLRPNFAIAMTVAPELFVPEHAIKAITIADEVLRGPVGMRTLDPSDYNYRPYYNNGEDSDDFATSKGRNYHQGPEWVWLYGYFLRAFHHFHFKTSPRCQNAAKEKPSSYLYQQLYYRLKGHRKWIFESVWAGLTELTNKDGEVCNDSSPTQAWSSACLLDLFYDLWDAYEDDS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: *: :. * . ...: : . * * .: . * :.: .*:: :*: .. *. . * * :. : :**:.: *: ::* ** . * * .**::****:* * *.* **: :**:.: .. *. :: :: :.: .: .: *:* **** :* *: **:. *. ..*:* .* ** : . : . * *. ::: .: : : : ::: * .: :.:: : .::* .:: . . : * . ... :. :: :* . : : : * *: **: :: .: *** . . :*:***: . .:** :**. : .*::**:: ***.****:* ***.**** :* :* : .* * *.*:*******:**.* :* **. .*:***:****:.*: * :*: ****:******:.* ...* .***::.** *:*.: : .: .**:*:* **** *. *:. * **.:::*::...* ** ****:.** : :* *:* * . ** : ::. :: .:. :.: ::.*.: . : ::. * :. :.: * : : : .: :. :* *:* . ::. * .* : . :: *:: :... . .:. : *: . * * :. *: .: ** * .* **.: * **** :*:: :* ***.**:. ***.*.* :** ** : : *::: * :*::* **:*.** *: : . . *. : .. : : *:: ::*: . : . : : :::******* . :******.**:*** :: ***. **: *:.*. *::********. * .*:*.*** *::: .:::* .*.* .** *:* :* **: :. .. * :: * :. * :*:::** *** ::* * .:*** :. .**::.**. :**********.*::* . * *.*****:*:*: ** :.:*:: : :. : : * : : ** ::..*:: :.*... . .::: **:* : : ..: ***** **.*::.***:* :.* :*: .. * **:**:*:**.* * *:*. *. : ::* ********:* *::*** * . : * : * * **.****.:.. * *. ***** * :*: :.** ", "identical_positions": 382, "similar_positions": 442, "identity": "21.97%" }, { "cls_id": "homologset.agr.HGNC:3211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29692-1", "uniprot_id": "EF1D_HUMAN", "id": "P29692-1", "name": "Elongation factor 1-delta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVAGASRQENGASVILRDIARARENIQKSLAG---------SSGPGASS----------GTSGDHGELVVRIASLEVENQSLRGVVQELQQAIS--KLEARLNVLEK--SSPGHRATAPQTQHVSPMRQVEPPAKKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPAL-VAKSSILLDVKPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFNKI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57776-1", "uniprot_id": "EF1D_MOUSE", "id": "P57776-1", "name": "Elongation factor 1-delta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVTSGSRQENGASVILRDIARARENIQKSLAG---------SSGPGASS----------GPGGDHSELIVRITSLEVENQNLRGVVQDLQQAIS--KLEARLSSLEK--SSPTPRATAPQTQHVSPMRQVEPPTKKGATPAEDDEDKDIDLFGSDEEEEDKEAARLREERLRQYAEKKAKKPTL-VAKSSILLDVKPWDDETDMAQLETCVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFDKI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B7W1-1", "uniprot_id": "A0A8M2B7W1_DANRE", "id": "A0A8M2B7W1-1", "name": "", "aln": "MRNRSHRNSSSNQSGSSERQTDRTTGCLSSGALEGLRSECSAIWFDRVQYERAESLYYVRLLQQQNGTTATASSSSSKRKQDTCQHGEQEACHHIVQSVWVNKPKYDQAESKFVGQNHAATPRSLQLQPSSQTPCDEGYQSQTPTPPTPASKPINGLPCLSLPPMGVWLQKPLFDKAEASFYQNLYNQNSTPRKPTNQSKSKRQNNNVAAPKKPVVCNQQDSNHPSTNQGAAGCYFLHADSERVWLDRGRYAEAESRFYGGAVGRSIKTPVNPSKQKQKKMTAADCLASERIWFDKPRYDEAERRFYEQMNGPTK--PKQDTGANTILQDIARARENIQKSLAGLKTTLQPSRGSAPKPSNPSHCSASSAGGSAADIGELAARMKSLELENQSLHKVVEDLRSALS--KMESRVSALERRSSSSSSSSSAPAVNGTRPAAAQKPPSAP--VKEEEDDDDDIDLFGSD-EEEDEEAERLKEQRLQEYAAKKAKKPAL-IAKSSILLDVKPWDDETDMSKLEECVRSVQMDGLLWGASKLMPVGYGIKKLQINCVVEDDKVGTDFLEEEITKFEDYVQSVDVAAFNKI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z1P2-1", "uniprot_id": "A0A8M6Z1P2_DANRE", "id": "A0A8M6Z1P2-1", "name": "", "aln": "MENQRRPRAKEETRQESTRNLPKSN-------------------------------------DGRRKRTRSSRSENLGSEEEGHSHHDLSSQGNKGEKVWFNRNLYEQADYDYQNLLSAG----------------------------------AGIPPVSSSPKDRIPRTLVFRAKRNGAQQSQDEDHQALTRSYVSRQLQRGSTHYRSSSEP----QKDRQFPKSSR------------KRVFSETER---------------------SPQKKDNITMSGLQGLAQENIWFDKSRYDEAERCFYEGANGIPQ--TSQERDASAILQDIAKARQNIQQSLAGVKTALQGS-KGHTRASKPRERKSSQNASKSEDQSELVSRLKSLELDNKNLHRVVDDLRATLS--KLESRMATLEK---TQAPATKGVTVIKAAPVQKPKVEEHN----GADDEDDDIDLFGSD--EEDEEAERIKAERVKEYSQRKAKKPAL-IAKSSILLDVKPWDDETDMSKLEECVRSVQMDGLLWGASKLVPVGYGIKKLQINCVVEDDKVGTDILEEEITQFEDYVQSVDIAAFNKI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL18-1", "uniprot_id": "EF1D_DROME", "id": "Q9VL18-1", "name": "Probable elongation factor 1-delta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVEALDKFWADKSRYDLAEKRFYE---GPQK--VTDRSHYSPLVSEIAKAREHIQNSLEK---------IDGVTLDD-------------GLNSELAKRLAQLEGEHKELKTQVSLLNELLT--ATVKRLETQLK---LTNGVSKEPEVEAKKPE--------------ANDDDDDVDLFGSDSEEEDGEAARIREERLAAYAAKKAKKVQI-IAKSNIILDVKPWDDETDLKVMETEIRKITQDGLLWGASKFVPVAFGIQKLSISCVVEDDKVSIDWLTEEIEKLEDFVQSVDIAAFNKI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32471-1", "uniprot_id": "EF1B_YEAST", "id": "P32471-1", "name": "Elongation factor 1-beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTDFSKIETLKQ-LNASLAD------------------------------KSYIEGTAVSQADVTVFKAFQSAYPEFSRWFN--HIASKADEFDS-----FPAASAAAAE--------------------EEEDDDVDLFGSDDEEADAEAEKLKAERIAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIPIGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQSTDIAAMQKL------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5PQJ6-1", "uniprot_id": "P5CR3_RAT", "id": "Q5PQJ6-1", "name": "Pyrroline-5-carboxylate reductase 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADEMSEPRRVGFVGAGRMAEAIAQGLIR---AGKVEAKQVLASAPTDKNLCHFRALG----------CQTTHSN--------------HEVLQNCPLVIFATKPQVLPAVLAEVAPVVTTEHIIVSVAAGISLSSMEELLPPKTRVLRVSPNLPCVVQEGAMVMTRGHHAGNEDAKLLQNLLEACGQCIEVPESYVDIHTGLSGSGVAFVCTFSEALAEG-----AIKMGMPSDLAHRIAAQTLLGTAKMLQQEGKHPAQLRTDVLTPAGTTIHGLHALEQGGFRAAAMSAVEAATCRAKELSKK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :: : : : . .. . . .. ..: : .: * :. .: . : : .. : * : .: : : : * * : . :* . :. ... . . . . *. ** : ", "identical_positions": 8, "similar_positions": 52, "identity": "1.35%" }, { "cls_id": "homologset.agr.HGNC:3212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1M4-1", "uniprot_id": "MCA3_MOUSE", "id": "Q9D1M4-1", "name": "Eukaryotic translation elongation factor 1 epsilon-1", "aln": "MAAAAELRLLEKSLGLKPGNKYSAQGERQIPVLQTNNGPSLMGLSTIATHLVKQASKEHLLGSTAEEKAMVQQWLEFRVTRVDGHSSKEDTQTLLKDLNSYLEDKVYLAGHNITLADILLYYGLHRFIVDLT-VQEKEKYLNVSRWFCHIQHYP----DIRQHLSSIVFIKNRLYANSH--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43324-1", "uniprot_id": "MCA3_HUMAN", "id": "O43324-1", "name": "Eukaryotic translation elongation factor 1 epsilon-1", "aln": "MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLT-VQEKEKYLNVSRWFCHIQHYP----GIRQHLSSVVFIKNRLYTNSH--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A4G8-1", "uniprot_id": "A0A8I6A4G8_RAT", "id": "A0A8I6A4G8-1", "name": "", "aln": "MAAAAELRLLEKSLGLKPGNKYSAQGERQVPVLQTNNGPSLMGLSTIATHLVKEANKEHLLGSTAEEKALVQQWLEFRITRVDGHSSKEDTQTLLKDLNSYLEDKVYLAGHNTTLADILLYYGLHRFICHWDDFVALFLWSNCHRSFSTTHVASSGSVGWLPPQSLVTLVHNMVLHSTLTFTLSVPYVFPKLQEVNTSKCIDFKTKDSLILSLACTHTHTEMQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QVE4-1", "uniprot_id": "F1QVE4_DANRE", "id": "F1QVE4-1", "name": "", "aln": "-MALRELNSLERFLGLKKANKYSTQGGKKVPVLQNNNGPALTGLVTIACHLVKEAKRPELLGDDAEQRAVVQQWLEHRITKLD-NCSKEEVKVILKDLNRYLEDKVYLAGNVFTLADILMYYGIHHIIVELA-IQEKECYLNVSRWFDHIQHYP----GIRHHLPPVVVLRNRVYPSGHH-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** **: ***. .****:** :::****.****:* ** *** ****:*.: ***. **::*:******.*:*::* :.**:: :.:***** ********:* ******:***:*::* . . : * * * : . . . :..::* : . ", "identical_positions": 79, "similar_positions": 46, "identity": "35.43%" }, { "cls_id": "homologset.agr.HGNC:3213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FR6-1", "uniprot_id": "EF1G_RAT", "id": "Q68FR6-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPEN---WRAFKALIAAQYSGAQIRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDD-GFCVFESNAIAYYVSNEE---------LRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGER-VTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----TERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQDLAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAVNQGKIFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8N0-1", "uniprot_id": "EF1G_MOUSE", "id": "Q9D8N0-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPEN---WRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDD-GFCVFESNAIAYYVSNEE---------LRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGER-VTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--TFQHVGKAVNQGKIFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26641-1", "uniprot_id": "EF1G_HUMAN", "id": "P26641-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPEN---WRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDD-GFCVFESNAIAYYVSNEE---------LRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGER-VTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAFNQGKIFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PE25-1", "uniprot_id": "EF1G_DANRE", "id": "Q6PE25-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPEN---WRAFKAQIAAQYSGARLKIASAPPAFTFGQTNRSPAFLGNFPLGKVPAYQGDD-GFCLFESNAIAHYLSNDV---------LRG-STPQASAQVLQWVSFADSEVIPPASAWVFPTLGIMQFNKQATEQAKEEVKRVLAVLNQHLNTRTFLVGER-ISLADITVVCSLLWLYKQVLEPAFRQPYPNVTRWFVTCVNQPQFKTVLGEVKLCEKMAQFDAKKFAEMQPKKEAPIKKEKGGKEGGKQQPQQQEKKEKKKEEKKAAPA-EEEMDECEAALASEPKAKDPFAHLPKSSFVMDEFKRKYSNEDTMTVALPYFWDHFDREGFSIWYAEYRFPEELTMAFMSCNLITGMFQRLDKLRKNAFASVILFGANNDSCISGIWVFRGQDLAFPLSDDWQIDYESYTWRKLDVDSEECKTMVKEYFAWEG--EFKHVGKPFNQGKIFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJH0-1", "uniprot_id": "EF1G_DROME", "id": "Q9NJH0-1", "name": "Elongation factor 1-gamma", "aln": "MVKGTLYTYPEN---FRAYKALIAAQYSGAQVKVADN---FKFGETNKSAEFLKKFPGGKVPAFETAE-GQYLSESNAIAYLLANEQ---------LRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNS--TAKQEAEAVLQQLNQKLQDATFLAGER-ITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQQQAQQQKQEKKPK-----EKKEAPKKAAEP-AEELDAADEALAAEPKSKDPFDALPKGTFNFDDFKRVYSNED-EAKSIPYFFDKFDAENYSIWFGEYKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASVCLFGEDGNSTISGIWVWRGQDLAFTLSPDWQIDYEVYDWKKLDAKSEETKKLVTQYFSWSG--TDKD-GRKFNQGKIFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29547-1", "uniprot_id": "EF1G1_YEAST", "id": "P29547-1", "name": "Elongation factor 1-gamma 1", "aln": "MSQGTLYANFR----IRTWVPRGLVKALKLDVKVVTP--------DAAAEQFARDFPLKKVPAFVGPK-GYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATEN-ISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLS---------PPQKKKEKKAPAAAPAASKKKEE--------------------AKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDYVP--AFDVAPDWESYDYAKLDPTNDDDKEFINNMWAWDKPVSVNGEPKEIVDGKVLK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36008-1", "uniprot_id": "EF1G2_YEAST", "id": "P36008-1", "name": "Elongation factor 1-gamma 2", "aln": "MSQGTLYINRS----PRNYASEALISYFKLDVKIVDL--------EQSSE-FASLFPLKQAPAFLGPK-GLKLTEALAIQFYLANQVADEKERARLLGS--DVIEKSQILRWASLANSDVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATEN-ISLGDLHAAGSWAFGLATILGPEWRAKHPHLMRWFNTVAASPIVKTPFAEVKLAEKALTY-------TPPKKQKAEKPKAEKSKAEKKKDE--------------------AKPADDAAP--AKKPKHPLEALGKSTFVLDDWKRKYSNDDTRPVALPWFWEHYNPEEYSIWKVGYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDFAP--AFDVAPDWESYEYTKLDPTKEEDKEFVNNMWAWDKPVVVNGEDKEIVDGKVLK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42936-1", "uniprot_id": "YG4D_YEAST", "id": "P42936-1", "name": "Putative elongation factor 1 gamma homolog", "aln": "MSDGTLFTDLKERKLIRTIVPRGLVRSLKLDVKLADP--------SDAQQLYEREFPLRKYPTFVGPHDEWTLTEAMAIDYYLIHLSSDKEAVRQLLGPEGDFKTRADILRWESLSNSDFLNEVCEVFFPLIGVKPYNATEFKAARENVDTIVSLYEKRLKKQQYLVCDDHETLADLISAAAFSLGFISFFDETWRSKHPEVTRWFNRVIKSRFFEGEFESFKMCETEMQ----------PIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***: * . ::: : ** : *:: . : *: ** . : : * ::: :* *:::.:. . ... * : . : : *. ::. : :*.*: .: * . *** . .. . *:.:. . . ", "identical_positions": 23, "similar_positions": 54, "identity": "5.0%" }, { "cls_id": "homologset.agr.HGNC:3214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05197-1", "uniprot_id": "EF2_RAT", "id": "P05197-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSG-VCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58252-1", "uniprot_id": "EF2_MOUSE", "id": "P58252-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSG-VCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLSAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13639-1", "uniprot_id": "EF2_HUMAN", "id": "P13639-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSG-VCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVM4-1", "uniprot_id": "A0A8N7UVM4_DANRE", "id": "A0A8N7UVM4-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIREIMDKKSNIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLYYELSENDSAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSG-VCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPDELFQTFQRIVENVNVIISTYGEGEHGPMGNIMVDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGDKKKGDLPPTERAKKVEEMMKKLWGDKYFDPSCGKFSKTANNADGKKLPRTFCQLVLDPIFKVFDAIMNFKKEETQKLIEKLEVKLDAEDKEKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQRYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMVPTTDKGRFYAFGRVFSGIVSTGQKVRIMGPNFTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFENSHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIVAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSDESDQVCLSKSPNKHNRLYMKSRPFPDGLAEDIDKGDVSSRQELKLRARYLAEKYEWEVAEARKIWCFGPDGTGPNILVDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHADAIHRGGGQIIPTARRVLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPIFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPYDVNSKPSQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P3J5-1", "uniprot_id": "EF2_DANRE", "id": "Q6P3J5-1", "name": "Elongation factor 2b", "aln": "MVNFTVDQIRAIMDKKSNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASARAGETRFTDTRKDEQERCITIKSTAISMYYELTENDLAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSG-VCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEDEGGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGE---AQLSPADRCKKVEDMMKKLWGDRYFDPAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDTEDKDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPGDDEAAMGIKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFDQAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSAESDQMCLSKSPNKHNRLYMKARPFPDGLAEDIDKGDVSSRQELKTRARYLADKYEWEVTEARKIWCFGPDGTGPNMLVDVTKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHTDAIHRGGGQIIPTARRVLYACQLTAEPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVMGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPKDAASKPCQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LYG5-1", "uniprot_id": "Q1LYG5_DANRE", "id": "Q1LYG5-1", "name": "", "aln": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKEC----KDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSG-VCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQ-----LGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IEY8-1", "uniprot_id": "A0AC58IEY8_DANRE", "id": "A0AC58IEY8-1", "name": "", "aln": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSKAGIVSSACAGETRFMDTRRDEQERCITIKSTAISIFYELADKDLAFIKEC----KDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSAGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLGPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPLIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQ-----LGPEEYIKKVEDMMKKLWGNSYFDSTTGKFSESATSPNGKKLPRTFVQLVLDPIFKVFDAIMNFKKEETAKLIEKMGIKLDAEEEKMEGKLLLKAVMRRWLQAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMVPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDPFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIFEDSGEHIIAGAGELHLEICLKDLEEVHG---LKKSDLFATYRETVSDGSKKMCLAKTPNQQSRLFFKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWVTREGILCAENMRGIRFDIHDATLTSTAIHRGPGQVITATRRVLYGCQLTAEPRLSEPVYLVEMQCPESVIGIIHAVLVRRRGVVFSESQVTGTPIYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQIMPGDPLNTTSKTAHIMADIRKRKGLPEANLALHRFLDKF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13060-1", "uniprot_id": "EF2_DROME", "id": "P13060-1", "name": "Eukaryotic translation elongation factor 2", "aln": "MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSG-VCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATYN-DDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFK----------------IDVVKLMNRLWGENFFNAKTKKWQKQKEADN----KRSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQDTRKRKGLKEGLPDLSQYLDKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32324-1", "uniprot_id": "EF2_YEAST", "id": "P32324-1", "name": "Elongation factor 2", "aln": "MVAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQK----TDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEG-VCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYADEVLG---DVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFG----------------VDKAKMMDRLWGDSFFNPKTKKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDPKADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPEQAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.**::* *** *:******. .********* ** .***::.* ***:** ***:***** *********:: *: ::* *.. .: .**:********************:*****:*** :.. **:*********:.*****::.:**:********: ::*:* * * **.*** ::** * :: : * *.:.***********::**: * ** . .::.:***: :*:. *: : : *:* :****:::* ****::*:* *:**: : *. :::. :** ***.*** :* *.:***:**.:******.** ** * ***** ** .:.:*.***.. **:*:***:**:*** ********:* * :* : ** ***:.****:**: *.***.:*****:**.*:* *.*** **:*:* **:****:** ::**:**********:*:** :. **********:*:**** : :.::****:**:*********:***. *. :* * ..:*****. *. .*:*:**::.*: :*: *: : :. *::* :.. :::: **: :::.* ::*::*********:*.***:: * ** ****:******:*.***.::** : *::*.:*.:: *.** : ***** **:* : ** *. : *.*:: **::* *:**** .:* ::. * ::** *..*.* ***:: :******.******.:* *.****.* *****. : .** : *: :: ** :*: * : * ", "identical_positions": 433, "similar_positions": 233, "identity": "50.0%" }, { "cls_id": "homologset.agr.HGNC:32151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KRE0-1", "uniprot_id": "ATD3A_RAT", "id": "Q3KRE0-1", "name": "ATPase family AAA domain-containing protein 3A", "aln": "MSWLFG-------IKGPKGEGTGPPLPLPPAQPGAESGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALNLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLNEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQ-VSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTAGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLK-VERPDSEASKPPHPSLLSC-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925I1-1", "uniprot_id": "ATD3A_MOUSE", "id": "Q925I1-1", "name": "ATPase family AAA domain-containing protein 3A", "aln": "MSWLFG-------IKGPKGEGTGPPLPLPPAQPGAEGGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLTEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLLGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQ-VSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTEGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLK-VERPDSQTNKPPHPSLLSC-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T2N8-1", "uniprot_id": "ATD3C_HUMAN", "id": "Q5T2N8-1", "name": "ATPase family AAA domain-containing protein 3C", "aln": "---------------------------------------------------------------------------MSKDALNLAQMQEQTLQLEQQSKLK------------------------------------------------------QLVN-EDLRKQEESVQK----------------------------------------------------HHQTFLESIRAAGTLFGEGFRAFVTDRDKVTATVAGLTLLAVGVYSAKNATAVTGRYIEARLGKPSLVRETSRITVLEALRHPIQQVSRRLLSRPQDVLEGVVLSPSLEARVRDIAIMTRNIKKNRGLYRHILLYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLYRTGQHSNKFMLILASCHPEQFDWAINACIDVMVHFDLPGQEERARLVRMYLNEYVLKPATEGKRRLKLAQFDYGRKCLEIARLTEGMSCRKIAQLAVSWQATAYASKDGVLTEAMMDACVQDFVQQHQQMMRWLK-GERPGPEDEQPSS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEX6-1", "uniprot_id": "ATD3A_DROME", "id": "Q9VEX6-1", "name": "ATPase family AAA domain-containing protein 3A homolog", "aln": "MSWLLGRNRQQPQPDQTAGFSEGGGAADPEGRTAGEKSGDSQLSRAERKAMEAYRFDSSALERAADAAKTLERSKHAREALELSKMQEATRQTEYNTKVKEYEAHIEQAKVEQKRIDHEERRKTLIEETKQQQQRAQYQDQLSRKRYEDQLLQQQRVQEENLRKQEESVQRQEAMRRQTIEHEIEMKEKNRLKLLEHELRAKARVDRENRDINLEKIRLKAQEHRTTVLEGIKTAGTVIGAGAEAMLTDWDKVLTAAGGLSLLALGVYTAKGATGVVSRYVEARIGKPTLVGETSRFAFLDALKNPLH-YLKRLRAKPTDALQGVVLNPKLEERLRDIAIATKNTRINKGMYRNVLMHGPPGTGKTMFAKKLAEHSGMDFAIMTGGDVAPMGKEGVTAIHKVFDWSHTSRRGLLLFVDEADAFLRKRSSEKISEDLRAALNAFLYRTSEQNPKFMLVLASNTPEQFDYAINDRLDEMVEFTLPGLEERERLLRLYFDKYVLQPAAAGAKRFKLDTFDYGKTCSKMAALCEGMSGREISKLGVSWQAAVYASEDGLLTEKMVLDRCYSAAQQHKQKMAWLSDQERADHKSITGTAAPPLTLTAKKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::**.*::*** * * * ::*:* * :: *:*********: *: *.**.*::***::* * .*::** *** ::..**:***:***:**.**.*..**:***:***:** ****::.*:**::*:: :** ::* *.*:**:*.*.** *:***** *:* : *:.:**::*::********:****** *****:************:*****:**:***: ********************::*********:*****:**.::. ****:*** *****:*** :* ** * ** *** **:*:*:::***:**: * :*:*: ****:.* ::* * *** *:*::*.*:*** .*:*:**:*** *: . .***:* * **. **.. : . ", "identical_positions": 239, "similar_positions": 112, "identity": "39.5%" }, { "cls_id": "homologset.agr.HGNC:32152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXX9-1", "uniprot_id": "ABEC4_RAT", "id": "Q6AXX9-1", "name": "Putative deaminase APOBEC-4", "aln": "MEPLYEEYLTHSGTIVKPYYWLSVSLNCTNCPYHIRTGEEARVPYTEFHQTFGFPW-STYPQTKHLTFYELRSSSGNLIQKGLASNCTGSHTHPESMLFERDGYLDSLIFHDSNIRHIILYSNNSPCDEANHCCISKMYNFLMNYPEVTLSVFFSQLYHTENQFPTSAWNREALRGLASLWPQVTLSAISGGIWQSILETFVSGISEGLTAVRPFTAGRTLTDRYNAYEINCITEVKPYFTDALHSWQKENQDQKVWAASENQPLHNTTP--------AQWQPDMSQDCRTPAVFMLVPYRDLPPIHVNPSPQKPRTVVRHLNTLQLSASKVKALRKSPSGRPVKKEEARKGSTRSQEANETNKSKWKKQTLFIKSNICHLLEREQKKIGILSSWSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q497M3-1", "uniprot_id": "ABEC4_MOUSE", "id": "Q497M3-1", "name": "Putative deaminase APOBEC-4", "aln": "MEPLYEEILTQGGTIVKPYYWLSLSLGCTNCPYHIRTGEEARVPYTEFHQTFGFPW-STYPQTKHLTFYELRSSSKNLIQKGLASNCTGSHNHPEAMLFEKNGYLDAVIFHNSNIRHIILYSNNSPCNEAKHCCISKMYNFLMNYPEVTLSVFFSQLYHTEKQFPTSAWNRKALQSLASLWPQVTLSPICGGLWHAILEKFVSNIS-GSTVPQPFIAGRILADRYNTYEINSIIAAKPYFTDGLLSRQKENQNREAWAAFEKHPLGSAAP--------AQRQPTRGQDPRTPAVLMLVSNRDLPPIHVGSTPQKPRTVVRHLNMLQLSSFKVKDVKKPPSGRPVEEVEVMKESARSQKANKKNRSQWKKQTLVIKPRICRLLER-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WW27-1", "uniprot_id": "ABEC4_HUMAN", "id": "Q8WW27-1", "name": "Putative deaminase APOBEC-4", "aln": "MEPIYEEYLANHGTIVKPYYWLSFSLDCSNCPYHIRTGEEARVSLTEFCQIFGFPYGTTFPQTKHLTFYELKTSSGSLVQKGHASSCTGNYIHPESMLFEMNGYLDSAIYNNDSIRHIILYSNNSPCNEANHCCISKMYNFLITYPGITLSIYFSQLYHTEMDFPASAWNREALRSLASLWPRVVLSPISGGIWHSVLHSFISGVS-GSHVFQPILTGRALADRHNAYEINAITGVKPYFTDVLLQTKR-NPNTKAQEALESYPLNNAFPGQFFQMPSGQLQPNLPPDLRAPVVFVLVPLRDLPPMHMGQNPNKPRNIVRHLNMPQMSFQETKDLGRLPTGRSVEIVEITEQFASSKEADEKKKKKGKK----------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*** *:: ***********.**.*:**************. *** * ****: :*:***********::** .*:*** **.***.: ***:**** :****: *:::..*************:**:***********:.** :***::******** :**:*****:**:.******:*.**.*.**:*:::*..*:*.:* * . :*: :** *:**:*:****.* .****** * . :: * : :. * *. ** .: * .* ** * *:*.*::**. *****:*:. .*:***.:***** *:* :.* : : *:**.*: * : : *::*::.::.: ** ", "identical_positions": 205, "similar_positions": 100, "identity": "51.64%" }, { "cls_id": "homologset.agr.HGNC:32153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B7U6-1", "uniprot_id": "Q3B7U6_RAT", "id": "Q3B7U6-1", "name": "", "aln": "MPPPPSTPPKTPNTMAFLHSSSIVQFECRHSNTSSRLLLILVLVLCGTLGTSVPSKQPRQSSLGTRSVSELSTVKVTQTKVQSDLELPQRLKLGLEKNPESQGEEPLCILRATAAAQTLASIIRSCYGPYGLQKFLVSAQGETVCTGHAAAILKALELEHPAARFVQELAQTQAENTGDGTAFVVLLTEALLEQAQYLLWAGLTPAQLREAFVTATAEVLTALPSLAICSLGPLEDPSWALYSVMSTHTLSNAEYLTKLVAQACWISREPNGSFKPESIVVCILQGGILTDSRIIPGIAICGKLCGRKTEVLNDARVALFNCPFGPSNPFAPATLRLSSPEELIRFRKQTEQ-VEMEIAELAMMGINVAVVLGEVNERSVDQADYCGVMVIQVKSRKEIVYLSDKLGVPLLNRILPPLEPGKCHKVYRMEFGESALIMFEWEREIAPFLSVVLRGPTIQGLRGAEQAVYYGIDAFSQLCQDPRLLPGAGATEMALARMLVDKGSRLDGPNGLAFQAFAQALSSLPKTLAENAGLAAQSVLAEMSGYHQAGNFVIGVGTDGLVNVAQEGIWDILRTKAQGLQAVTGLVQQLVTVDQIIVARKTPRYRLIPQSAQNANTSSP---LRAKFFGKYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NM43-1", "uniprot_id": "TCPQL_HUMAN", "id": "A6NM43-1", "name": "Putative T-complex protein 1 subunit theta-like 1", "aln": "----------------------------------------------------------------------------MDSTVPSALELPQRLALNPRESPRSPEEEEPHLLSSLAAVQTLANVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAAQTQAENSGDGTAFVVLLTEALLEQAEQLLKFGLPRPQLREAYATATAEVLATLPSLAIQSLGPLEDPSWALHSVMNTHTLPPMNHLTKLVAHACWAIKELDGSFKPERVGVCTLHGGTLEDSCLLQGLAISGKLCGQMAAVLSGARVALFACPFGPAHPNAPATACLSSPADLAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQARSRMEIIYLSEVLDTPLLPRLLPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTVVLRGATTQGLRSAEQAVYHSIDAYFQPCQDPRLIPGAGATEMALAKMLSDKGSRLEGPNGPAFLAFARALKYLPKTLAENAGLAVSDVVAEMSGVHQGGNLLMGVGAEGIINVAQEGVWDTLIVKAQGFRAVAEVVLQLVTVDEIVVAKKSPTHQQIWNPDSKKTKKRPPPVEKKKILGMNN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* * ******* *. .:.*.* ** :* : **.****.:**.****:* *****: :******* *:***:********* :::* *******:******************: ** **. .*****:.*******::****** ************:***.****. ::******:*** :* :****** : ** *:** * ** :: *:**.*****: : **..****** *****::* **** **** :* :* * ::* :* ::.:** ***********:*.:: ** *::***.:** **:***: *..*** *:*** .****::*** *:*:. ::**** :* *:*****.* ****.******:.***: * ******:***********:** ******:**** ** ***:**. ************...*:***** **.**:::***::*::******:** * .****::**: :* ******:*:**:*:* :: * :. .: ... * : *::* :", "identical_positions": 342, "similar_positions": 127, "identity": "54.03%" }, { "cls_id": "homologset.agr.HGNC:32156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M8M9-1", "uniprot_id": "LRC52_MOUSE", "id": "Q5M8M9-1", "name": "Leucine-rich repeat-containing protein 52", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSLASGPSSKLLLFSLGMGLVSGSK--------CPNKCVCQDQ-EVACIDLHLTEYPADIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFRLIYLDLSSNNLTSISPFSFSVLTNLVRLNISHNPHLLYLDKYVFANTTSLRYLDLRNTGLHIIDHNGFHHLVVLQTLYLSGNPWICNCSFLDFTIHLLVSHMDHPDAQNATCTEPAELKGWPITKVGNPLQYMCITHLDQQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQN-ALRTSSGDDTEDETGSRFANQIFRSNTHLGPIRRFPELI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FFB1-1", "uniprot_id": "F7FFB1_RAT", "id": "F7FFB1-1", "name": "", "aln": "MPDSSRERAYLPTKNHSLPPRGRGEKPLSQSLPRLLTSQKCQLATSLSGGSPLAPLHLQRQGKGETFQSCQVGKLPTALRTELAAEPPSRQQGTGPRVSTSVQFSCNGKLLCTKLECYSFFQHPSPALPHPSAAFRSEGQLAPALRKVEGGELWLLTMSLASGPSPKLLLFSLGMGLVSGSK--------CPNNCLCQDQ-EVACTDLQLTEYPTDIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFKLLYLDLSSNNLTSISPFSFSILTNLVRLNISNNPHLLYLDKYIFANTTSLRYLDLRNTGMQIIDHTGFHHLVVLQTLYLSGNPWKCNCSFLDFTIHLLVSHMDHPDAQNATCTEPPELKGWPITKVGNPLQYMCITHLDHQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQN-ALRKSSGDDTEDETGNRITNQMFRSNTHLAPVRRFPELI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N7C0-1", "uniprot_id": "LRC52_HUMAN", "id": "Q8N7C0-1", "name": "Leucine-rich repeat-containing protein 52", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSLASGPGPGWLLFSFGMGLVSGSK--------CPNNCLCQAQ-EVICTGKQLTEYPLDIPLNTRRLFLNENRITSLPAMHLGLLSDLVYLDCQNNRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNPHLLSLHKFTFANTTSLRYLDLRNTGLQTLDSAALYHLTTLETLFLSGNPWKCNCSFLDFAIFLIVFHMDPSDDLNATCVEPTELTGWPITRVGNPLRYMCITHLDHKDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQN-TRHKSSEED-EDEAGTRVEVSRRIFQTQTSSVQEFPQLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA04-1", "uniprot_id": "A0AB32TA04_DANRE", "id": "A0AB32TA04-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MRVLPEPSAQSLRLVFLLVFVMDVAPSPALTAGCPDRCVCDDQLVVQCAGQQLSDFPVDLPLATRQLIISNNRIGDLPALQLNYLSDLVYLDCSNNSLTEISESTFGNLRKLAYLDLSFNSLAQIEDRTFGPLASLVMLRMTDNPGLSEIHPDAFAENAALQVLDVSRNNLTALNISSLIALPALRSLGLSGNPWRCDCDTEDLCLWIQIEGFKFQDEGQTVCQGPPDMLGQRLAEVGMQLRSECHQGLGYWDYLFFIAIGFVIFSAGTVSAWVMGVLMVLYERYSKRKSEELDSDDEEETVTRGPGGGGGNHGNGDLNKPGMQV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . *.. * : : : :* . **:.*:*: * * * . :*:::* *:** **:* :.:*:* .***::*. *********.** : *: : ** .: :* ***** *.*:.*. :*. *:.** *.::.** * :. **:.::*: **: ...: :: .: * .*.:* ****** *:*. *: : : : :. * ::.* *.:: * ::.** *: * *. **:*:: *** **:****:**: ** ***:. : :.*. * :** . .: . * : ", "identical_positions": 106, "similar_positions": 103, "identity": "21.99%" }, { "cls_id": "homologset.agr.HGNC:32159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTB3-1", "uniprot_id": "E9PTB3_RAT", "id": "E9PTB3-1", "name": "Mitochondrial GTPase 1", "aln": "--MRLWPQAWS-AVGAAWRECFPLQGHDV-ARWFPGHMAKGLKKMQSSLKLVDCVIEVHDARYIPFSGRNPLFQELLG---LKPHLLVLNKMDLADLTE--QQKIVQHLEEKG--LRNVIFTNCIK--DENIKQIIPKVTELIGCSYRYHRAENPEYCIMVVGVPNVGKSSLINSLRRQHLRTG-------KAARVGGEPGITRAVTSRIQVCERPL-----MFLLDTPGVLAP-RIQSVETGLKLALCAACLAGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALAS---ASDHIEWVLKNVAIKLGKTRKVKVLTGTGNVNVIQPDYAIAARDFLR----TFR------SGRLGQVMLDRDIIPAC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2R6-1", "uniprot_id": "MTG1_MOUSE", "id": "Q8R2R6-1", "name": "Mitochondrial ribosome-associated GTPase 1", "aln": "--MRLWPQAWG-AVRGAWRECFPLQGHDV-ARWFPGHMAKGLKKMQSSLKSVDCVIEVHDAR-IPFSGRNPLFQELLG---LKPHLLVLNKMDLADLTE--QQKIVQRLEEKG--LSNVLFTNCVK--DENIKQIVPKVMELIRCSYRYHRAETPEYCIMVVGVPNVGKSSLINSLRRQHLRTG-------KAARVGGEPGITRAVTSRIQVCERPL-----VFLLDTPGVLAP-RIESVETGLKLALC-----GTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALAS---ACDQIEWVLKNVAIKLRKTRKVKVLTGTGNVNVIQPDYAMAARDFLR----TFR------SGLLGQVMLDRDIIPAC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT17-1", "uniprot_id": "MTG1_HUMAN", "id": "Q9BT17-1", "name": "Mitochondrial ribosome-associated GTPase 1", "aln": "--MRLTPRALCSAAQAAWRENFPLCGRDV-ARWFPGHMAKGLKKMQSSLKLVDCIIEVHDAR-IPLSGRNPLFQETLG---LKPHLLVLNKMDLADLTE--QQKIMQHLEGEG--LKNVIFTNCVK--DENVKQIIPMVTELIGRSHRYHRKENLEYCIMVIGVPNVGKSSLINSLRRQHLRKG-------KATRVGGEPGITRAVMSKIQVSERPL-----MFLLDTPGVLAP-RIESVETGLKLALC-----GTVLDHLVGEETMADYLLYTLNKHQRFGYVQHYGLGS---ACDNVERVLKSVAVKLGKTQKVKVLTGTGNVNIIQPNYPAAARDFLQ----TFR------RGLLGSVMLDLDVLRGHPPAETLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXJ5-1", "uniprot_id": "A0A8M9PXJ5_DANRE", "id": "A0A8M9PXJ5-1", "name": "Mitochondrial GTPase 1", "aln": "--MRIYHSLLN---AAKFRSVFDFGERDV-THWFPRHMAKGLKQMRANLRNVDCIIEIHDAR-IPFSGRNSSFQESLD---VRPHLLVLNKMDVADISK--KQSILKQFEREG--VKNVLFTDCLRQHDENVKKIVPLVSKLIESTSRFHREEERCYCLMVIGVPNVGKSSLINALRRTYLKKG-------KASKVGAEPGITKAVLTKIQVCERPI-----IHLLDTPGVLPP-RIENIETGMKLALC-----GTVLDHLVGEDVIADFLLFSLNRLERFSYVEKYSLEE---PCDDIQHVLKCIAVKLGKTRRVKAITGVGNITVQLPDYSAAAYDFIR----AFR------KGELGKVMLD--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCU5-1", "uniprot_id": "MTG1_DROME", "id": "Q9VCU5-1", "name": "Mitochondrial ribosome-associated GTPase 1", "aln": "-----MAAQLN-----PFRNAFRLPSKQR-INWFPGHMTKGMRQIQQKLRNVDCIVEIHDAR-IPLAGRNSQFFDTITGSGVKPHILVLNKVDLLGAKQ--QKSVLQQLRRQQPELQHILFTNCKDQRNNGVLDILPLATRLVSESSRFNRTQAAEHNLMIIGVPNVGKSSVINVLRNVHLKKK-------SAARVGAEAGITRSVGERIKIQENPP-----VYMIDTPGILQP-SIKDDEMGMKLALV-----GCLPDHIVGEDLIADYLLYWLNSHRKYDYVEMLKLSSG--PSDDISAVLAEYAHREELFHKVKQYDGR--VEVMT-NLLAAARKFIH----FFR------SGQLGHMNLDEPSGFR--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03151-1", "uniprot_id": "MTG1_YEAST", "id": "Q03151-1", "name": "Mitochondrial GTPase 1", "aln": "MHINVRGTRKIISNVSSFTPRYEFPKYSMPLTDFKGHQVKALKTFEKLLPQMNMIIELRDIR-APLSTRNVVFDRIARKEHDVMKLVVYTRKDLMPGNKPYIGKLKNWHEELG---EKFILLDCRN--KTDVRNLLKILEWQNYELETNGGYLPMGYRALITGMPNVGKSTLINSLRTIFHNQVNMGRKFKKVAKTGAEAGVTRATSEVIRVTSRNTESRNEIYLIDTPGIGVPGRVSDHNRMLGLALC-----GSVKNNLVDPIFQADYLLYLMNLQNLNDGRTELYPGSTNSPTNDIYDVLRRLQVNKSQNEKSTAIEWTNKWRLHGKGIIFDPEVLLNNDEFSYKNYVNDQLEKLGDLSYEGLSNKLKGNPNQVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . * * .*.:: :. * :: ::*::* * *:: ** * :::* .: *: .: .: : . :.:: :* . .: .:: : :: *:******::** ** . . ..::.*.*.*:*::. *:: .. :.::****: * :.. : : *** * : :::*. **:**: :* . . . :.: ** . .: . : . . ::. :: ** : : ", "identical_positions": 49, "similar_positions": 102, "identity": "12.96%" }, { "cls_id": "homologset.agr.HGNC:32166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JIZ3-1", "uniprot_id": "Q8JIZ3_DANRE", "id": "Q8JIZ3-1", "name": "", "aln": "MMSYIKQPHYAVNGLTLSASGMDLLHTAVGYPATPRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQTSGQPKPRPPKKKSSP--------------PPDLTSDPGTSSSVVAAPTPTVP-----PSVSAGTAPVSVWSPTSLSPLPDPLCG------SGTPCVQRPAP----------YPMSYGQPSSYSQGYGSS---PYFSGLDCSPYLSPMT-----------TQLSASGGALSPLTVPSMGGSLSQSPSLSSQGYSTASLGFSSVDCLDYKDQQA--WKLNFS--TVDCLDHK------FQVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90267-1", "uniprot_id": "OTX1A_DANRE", "id": "Q90267-1", "name": "Homeobox protein OTX1 A", "aln": "MMSYLKQAPYAMNGLGLGGATMDLLHPSVGYPTNPRKQRRERTTFTRTQLDILESLFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQSSTNSKIRPAKKKPSPSRESPGSESSGHFTPPAVSSSSSSSSSSSGSNPSALSGVGLISSSSSGTPVPSIWSPAPVSPVPAPPSLPDISPPASASCMQRAMSSGGGTTGVPSYPMPYNQAPSYAQGYPTSNAASYFGGMDCGSYLAPMTGHAHHHPHAHHSQLSTAAAVSGHHHPHHIGQSSGHHP--HHQGYGGTALPFSSSDCLDYKEQVASSWKLNFSSAAADCLDYKDQAAWRFQVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A6NFQ7-1", "uniprot_id": "DPRX_HUMAN", "id": "A6NFQ7-1", "name": "Divergent paired-related homeobox", "aln": "-----------MPGSEDLRKGKDQMHS-----------HRKRTMFTKKQLEDLNILFNENPYPNPSLQKEMASKIDIHPTVLQVWFKNHRAKLKKAKCKHIHQKQETP--QPPIP--------------------EGGVSTSVGLRNADTLP-----RLPNAAHPIGLVYTGHRVPSFQLILYP------------------------------NLKVPANDFIGHRIVHFG--------------------------------CCRDPNIYCLYPILESQVCAP----------SFHSGSPACSSNQSRER----------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * :*. :*:** **:.**: *: ** :. **: :::*:* **:: : :******:*** :: : : : : * : . * . . *:* . ::. .:. . ::: :... ... *: . . : * * :: .* * . :.: ", "identical_positions": 37, "similar_positions": 61, "identity": "10.88%" }, { "cls_id": "homologset.agr.HGNC:3218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35568-1", "uniprot_id": "FBLN3_RAT", "id": "O35568-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLQTVFLTMLTLALVKSQVTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETPAAEASSGAATGTIAARSMATSGVIPGGGFIASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRLDQVCINLRGSFTCHCLPGYQKRGEQCVDIDECSVPPYCHQGCVNTPGSFYCQCNPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPQNPCQDPYVLTSENRCVCPVSNTMCRDVPQSIVYKYMNIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLTGPREHIVGLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPB5-1", "uniprot_id": "FBLN3_MOUSE", "id": "Q8BPB5-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLQTLFLTMLTLALVKSQYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12805-1", "uniprot_id": "FBLN3_HUMAN", "id": "Q12805-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T0U7-1", "uniprot_id": "A0AB32T0U7_DANRE", "id": "A0AB32T0U7-1", "name": "", "aln": "MICSCINSLCNPRAFLQQRETTCSHSRTHTHTHTHTQLHQISSSSTHTAADLQHSSSLTPAEMWTVSLMMAALACVLSQEAEESVSYTRCTEGYEYDPFKEVCTDIDECVLVSDACKAGMKCINHYGGYLCLPQNAQIFINKENE-----------------------------------ASQSSDSVPQTHTETN-----------HRSAANGGS--QCSAGFTRDQHNYCHDVDECSQGLHTCGSDQICYNSRGSYSCQCQPGYQRHGEQCVDRNECLLSHYCMHRCVNTAGSYYCECNDGYQLASNNHSCVDVNECEVSQPCQHQCFNLLGSFICQCEQGYELGPDAVSCVDIDECSFSSYMCQYACVNSEGGYSCTCPDGYQIHRTRMCQDINECETAAHECREDEMCWNYYGGHRCYPRNPCLEPYVRTSENRCSC-QSAAACRGLPQSIVYKYMNMHSERSVPADIFQIQATNIFSSAHYTFRIKDGNDGGQFFLRRFSSAGAMLVLTQSLEGPQELIVDLEMITQHSLMNYRSSSLLRLTIIVGPFPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * * :** * ** :**:::**:**:***:**.:: *.***** :*.****.****:**********:.***::*:*: ** :: : *: :* * :* .:* . **:**: :.:** *:*:***: * *.* **:* * ***::*:* ****::****** :** :. ** : ****.**:**:*. *:***:**::***:***:.*: * :**:*:********:*****..* :.* ***** ***:*** ***. * :** **:**:: *:* *********: ***********:**.****:*** : *: *.**** * * : ** :*********.::*:****:******** *::.: *****.**:.*:*:**: *...*****.:** **:* **.***:* *: .:*:**:**********.*", "identical_positions": 261, "similar_positions": 118, "identity": "47.03%" }, { "cls_id": "homologset.agr.HGNC:3219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y8F2-1", "uniprot_id": "A0A8I5Y8F2_RAT", "id": "A0A8I5Y8F2-1", "name": "EGF-containing fibulin-like extracellular matrix protein 2", "aln": "MLPFASCLPGSLLLWAFLLLLLGAASPQDSEEPDSYTECTDGYEWDADSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVISDLHSEGPPPPAASAQHPNPCPPGYEPDEQESCVDVDECTQAIHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCNQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECETGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYVQVSDNRCLCPASNPLCREQPSSIVHRYMSITSERSVPADVFQIQATSVYPGAYNAFQIRAGNTQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVJ9-1", "uniprot_id": "FBLN4_MOUSE", "id": "Q9WVJ9-1", "name": "EGF-containing fibulin-like extracellular matrix protein 2", "aln": "MLPFASCLPGSLLLWAFLLLLLGAASPQDPEEPDSYTECTDGYEWDADSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVISDLHGEGPPPPAAHAQQPNPCPQGYEPDEQESCVDVDECTQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCNQGYELHRDGFSCSDIDECGYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECETGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYVQVSDNRCLCPASNPLCREQPSSIVHRYMSITSERSVPADVFQIQATSVYPGAYNAFQIRSGNTQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95967-1", "uniprot_id": "FBLN4_HUMAN", "id": "O95967-1", "name": "EGF-containing fibulin-like extracellular matrix protein 2", "aln": "MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ************:******:*****.****************.*****************************************.***.******.. **:***** *****:*:********:**:*************************************************************************************************:******************.**********:*****************************:******************************:***:************************:******************************:**:************************************************************", "identical_positions": 418, "similar_positions": 22, "identity": "94.36%" }, { "cls_id": "homologset.agr.HGNC:32190", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K8H7-1", "uniprot_id": "A0A0G2K8H7_RAT", "id": "A0A0G2K8H7-1", "name": "", "aln": "MRT-NTQAVPATNMAQMQ------TLVLFSTLLILCVSAASPEVWVQVQMEATNLSFFSVHCGVLGCNHISLVTVSWKGFVDARETKLAVLHPEFGTQQWAPASQAHWETPISISVTLTLEQSKARSSLANTTFCCEFVTFPHGSRVACRDLH-SSDPGLSAL-TPAPSLQADLAGILGTSGFFLFGFIFILCLRWWQRHRCSRKSQLSLSRTQAQ------------------------------METPLPH----------------------LASI----QGSFIFVDNGLYTLA------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1B0GS01-1", "uniprot_id": "A0A1B0GS01_MOUSE", "id": "A0A1B0GS01-1", "name": "", "aln": "MRTGNTQAAHATNMGQMQ------TLVLFSTLLTLCVSEASPEVWVQVQMEATNLSSFSVHCGVLGYSLISLVTVSCEGFVDAGRTKLAVLHPEFGTQQWAPARQAHWETPNSVSVTLTMGQSKARSSLANTTFCCEFVTFPHGSRVACRDLH-RSDPGLSAP-TPALNLQADLVRILGTSGVFLFGFIFILCLRWQQRHWCLSKSQPSLTSTQAQ------------------------------VETQPPH----------------------LAST----HSSFISMENGLYALA------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DKI7-1", "uniprot_id": "PVRIG_HUMAN", "id": "Q6DKI7-1", "name": "Transmembrane protein PVRIG", "aln": "MRTEAQVPALQPPEPGLEGAMGHRTLVLPWVLLTLCVTAGTPEVWVQVRMEATELSSFTIRCGFLGSGSISLVTVSWGGPNGAGGTTLAVLHPERGIRQWAPARQARWETQS--SISLILEGSGASSPCANTTFCCKFASFPEGSWEACGSLPPSSDPGLSAPPTPAPILRADLAGILGVSGVLLFGCVYLLHLLRRHKHRPAPRLQPSRTSPQAPRARAWAPSQASQAALHVPYATINTSCRPATLDTAHPHGGPSWWASLPTHAAHRPQGPAAWASTPIPARGSFVSVENGLYAQAGERPPHTGPGLTLFPDPRGPRAMEGPLGVR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .. . :: **** .** ***: .:*******:****:** *:::**.** . ******* * .* *.******* * :***** **:*** *::* : * * *. *******:*.:**.** ** .* ******* *** *:***. ***.**.:*** :::* * ::* : * * : .** ::* ** ** :.**: ::****: * ", "identical_positions": 119, "similar_positions": 50, "identity": "36.28%" }, { "cls_id": "homologset.agr.HGNC:32203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LLQ8-1", "uniprot_id": "A0ABK0LLQ8_RAT", "id": "A0ABK0LLQ8-1", "name": "", "aln": "MKHPFPQFPPILVIYCFCMLQIPSSGASPPLAGPPDGLDAVDPERLAHFLNQRETCSNQPKESRDVYKRFLFHYSRAWKSTHPVNSEFAPVHPLMRLAAKLPSRRMKRLPRLLHTDSRMATIDFPKKDPTTSLGRPFFLFRVTCWFLERALRSSWSLLCLHLRSLENRSSHLS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5H8A1-1", "uniprot_id": "NMS_MOUSE", "id": "Q5H8A1-1", "name": "Neuromedin-S", "aln": "MKHPLPHYSPILFIYCFCMLQIPSSGASPPLADSPDGLDIVDPERLAYFLKQREIHSNQPKENQDVYKRFLFHYSRTRKPTHPVSAEFAPVHPLMRLAAKLASRRMKRLPRLLRLDSRMATVDFPKKDPTTSLGRPFFLFRP--------------------RNGRYTDNNFQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5H8A3-1", "uniprot_id": "NMS_HUMAN", "id": "Q5H8A3-1", "name": "Neuromedin-S", "aln": "MKHLRPQFPLILAIYCFCMLQIPSSGFPQPLADPSDGLDIVQLEQLAYCLSQWAPLSRQPKDNQDIYKRFLFHYSRTQEATHPVKTGFPPVHPLMHLAAKLANRRMK---RILQRGSGTAAVDFTKKDHTATWGRPFFLFRP--------------------RNGRNIEDEAQIQW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCJ8-1", "uniprot_id": "A0A8M3BCJ8_DANRE", "id": "A0A8M3BCJ8-1", "name": "", "aln": "-MGFSAICCLLWFISCFYS-AVESFPSPLTDCDDNDSSDYIQGSAVLSSLCALQWRDQEQEHIQNVFKRFLFHYSKAQNSLGSVERESHSVHPLMRLSPRLSLRRKK---QQQLKNACGASARNIRDILCSYLG---FSLTP----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * ** : * . . .. *. * :: . : * ..: :. ::::********:: :. .*. .*****:*:.:*. ** * : .: *: :. : * * : ", "identical_positions": 29, "similar_positions": 41, "identity": "16.48%" }, { "cls_id": "homologset.agr.HGNC:32204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1IH00-1", "uniprot_id": "GOGA2_DANRE", "id": "A1IH00-1", "name": "Golgin subfamily A member 2", "aln": "------------MADQNRQIKLAAAKKKLKEFQQKTIPSTGSAGPKKKRKVKGDQTDAPADRRSPENERVDVSQELEEAGAEHVSNPASAINTDNSAPQNYPADANGDEHPLENNRPLSSTESLRQLSQQLNGLLSESSTHINGDSDPPAVNEKELETRNQELSAALDSSALTNTQLTSKLETLTKQSQELSDQLQKERKEFEQKFTKEQGAMREQLQVHIQTIGILVSEKSELQTALSYTQQAARQKAAEAEDLSSRLQASKQRVSELERTLSSVSTQQKQHERHNKELEKERDSLRLEIIRFNNVSEESRQQSSELSEQLKLRVNENSALKLELEDLRKRLEMADVMLQQFSSQSGPPSEHQQLQLLLEEKHQLENHATQLMESVAQLQAERDQYAVQMQEDGRVWKDKTEQLLSQVRLMSEERDSTAAQILELQERIMELENTAAVMSTEQEPQASSQLSGPSETELALQETLRSLQEERDALSLQFQAQVRDNEQLSRLVQEQEVKLQELERQAERASEDAQDRLRILEDVQSDKATISRALTQNRELKDQLAELQNGFVKLTNENMELTSALQSEQHVKKEIARKMGQLQEDLHNAKEQLLESSSELTSVQEQRDQYLAHLQQYSAGYQQLLAEREHLQKQFLQQTQLMDRLQHDEVQGKVQLEQSHMQLQEVQEKLSRLVRDNEELKTE--VQELLNGSIMNTSHRDEGDGLESQTLPESFQKSQIAIPEDFESREEMKEFIHSVLSRVEAERDEMSRRLEEERRIHQDTRQQLTALSHDHHHHHHHEPHSTCAETDGSEGVPVEVHEALRVAMEKLQERFTKLMQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQNQRAIMKQKHVEKEQYINMLAKDKEEMKTKLAELQDLVMRLVGERNEWYSRYMSAVGNRDLLNSNAEQIHPAERRMEISGVDAPAVLDMSTAMDVSSSPQSSTAEIQSQSSERPAADPISSPSLRPQEDGTARQIMQLLQEIQNPQSRPAPFLGENPCIPFFYRPDEHDEVKILVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CG33-1", "uniprot_id": "GOG6D_HUMAN", "id": "P0CG33-1", "name": "Golgin subfamily A member 6D", "aln": "MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPG-----------------------------------------------------------------------------------------DSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKK--------TNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRS--------------------------------------------------------------------SSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQ-------LQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQE---EMLREQEAQRVREQE----------RLCEQNERLREQQKTLQEQGERLRKQEQRLR---KQEERLRKEEERLQ-KQEKRLWDQEERLWKKEERLQKQEER----------------LALSQNHKLDKQLAEPQCSFEDLNNEKKS----ALQLEQQVKELQEKLDEEHLEAASQRNQ--QLETQLSLVALPGEGDGGQHLDSE--EEEAPRPTPNIPEDLESRE--------------------------------------------------------------------------------ATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKE-EEMKVKLLELQELVLPLVGN-HEGHGKFLIAAQN------PADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPAPGVAREGS-----------------PHNNPTVQQIVQLSPVMQDT-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "---------MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQPP------------------------------------------------EQSALPTAASYFAQNESEHNGGLADASSLQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQN-QLRLEQLQQHCQDQQSTGEQQRQQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDE---------------------------------------------------------SSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFKEASQVQPSKEETSEQK---ALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHENVELQ----------RQQLMLQQQLDRLRHYEAKAYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHNHHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLP------------------------------------------------------TAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLGVELPADAA--------------QAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTE--------------------QPSHNHAGDHLNCCMGKFEVV-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *****:*****:**: . . : . . :. . . . *:: **. :: .: :: . :*:: : ::: : .* : ::*:: * :: :. . ::* .:*: * *: .**:: *. *.: : : :. : :: *: . *: :. * : ::*. : . : ::: :: . : *.. :: *:. : : . * :. *:: *::: : :. : : . : . : :: *:* * * : :: : * ** .:::* **: :* ::: .* ..*: .:* : . :: * :*:: ....: ... * ..:*:: . :. : . : . : : * . : :.: : . .. : *: ... .. : . ..:: . * * .: ** .*. . * :* .. *: : * :::*:.* : : :. * :.: : *::: *: *:.**: * : . *.: .. . * . * . .. * .: : :: :: ", "identical_positions": 78, "similar_positions": 230, "identity": "7.49%" }, { "cls_id": "homologset.agr.HGNC:32205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1IH00-1", "uniprot_id": "GOGA2_DANRE", "id": "A1IH00-1", "name": "Golgin subfamily A member 2", "aln": "------------MADQNRQIKLAAAKKKLKEFQQKTIPSTGSAGPKKKRKVKGDQTDAPADRRSPENERVDVSQELEEAGAEHVSNPASAINTDNSAPQNYPADANGDEHPLENNRPLSSTESLRQLSQQLNGLLSESSTHINGDSDPPAVNEKELETRNQELSAALDSSALTNTQLTSKLETLTKQSQELSDQLQKERKEFEQKFTKEQGAMREQLQVHIQTIGILVSEKSELQTALSYTQQAARQKAAEAEDLSSRLQASKQRVSELERTLSSVSTQQKQHERHNKELEKERDSLRLEIIRFNNVSEESRQQSSELSEQLKLRVNENSALKLELEDLRKRLEMADVMLQQFSSQSGPPSEHQQLQLLLEEKHQLENHATQLMESVAQLQAERDQYAVQMQEDGRVWKDKTEQLLSQVRLMSEERDSTAAQILELQERIMELENTAAVMSTEQEPQASSQLSGPSETELALQETLRSLQEERDALSLQFQAQVRDNEQLSRLVQEQEVKLQELERQAERASEDAQDRLRILEDVQSDKATISRALTQNRELKDQLAELQNGFVKLTNENMELTSALQSEQHVKKEIARKMGQLQEDLHNAKEQLLESSSELTSVQEQRDQYLAHLQQYSAGYQQLLAEREHLQKQFLQQTQLMDRLQHDEVQGKVQLEQSHMQLQEVQEKLSRLVRDNEELKTE--VQELLNGSIMNTSHRDEGDGLESQTLPESFQKSQIAIPEDFESREEMKEFIHSVLSRVEAERDEMSRRLEEERRIHQDTRQQLTALSHDHHHHHHHEPHSTCAETDGSEGVPVEVHEALRVAMEKLQERFTKLMQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQNQRAIMKQKHVEKEQYINMLAKDKEEMKTKLAELQDLVMRLVGERNEWYSRYMSAVGNRDLLNSNAEQIHPAERRMEISGVDAPAVLDMSTAMDVSSSPQSSTAEIQSQSSERPAADPISSPSLRPQEDGTARQIMQLLQEIQNPQSRPAPFLGENPCIPFFYRPDEHDEVKILVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A6NDN3-1", "uniprot_id": "GOG6B_HUMAN", "id": "A6NDN3-1", "name": "Golgin subfamily A member 6B", "aln": "MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPG-----------------------------------------------------------------------------------------DSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKK--------TNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRS--------------------------------------------------------------------SSCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQ-------LQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQE---EMLREQEVQRVREQE----------RLCEQNERLREQQKTLQEQGERLRKQEQRLR---KQEERLRKEEERLQ-KQEKRLWDQEERLWKKEERLQKQEER----------------LALSQNHKLDKQLAEPQCSFEDLNNEKKS----ALQLEQQVKELQEKLDEEHLEAASQQNQ--QLETQLSLVALPGEGDGGQHLDSE--EEEAPRPTPNIPEDLESRE--------------------------------------------------------------------------------ATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKE-EEMKVKLLELQELVLPLVGN-HEGHGKFLIAAQN------PADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPAPGAAREGS-----------------PHDNPTVQQIVQLSPVMQDT-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "---------MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQPP------------------------------------------------EQSALPTAASYFAQNESEHNGGLADASSLQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQN-QLRLEQLQQHCQDQQSTGEQQRQQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDE---------------------------------------------------------SSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFKEASQVQPSKEETSEQK---ALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHENVELQ----------RQQLMLQQQLDRLRHYEAKAYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHNHHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLP------------------------------------------------------TAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLGVELPADAA--------------QAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTE--------------------QPSHNHAGDHLNCCMGKFEVV-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *****:*****:**: . . : . . :. . . . *:: :**. :: .: :: . :*:: : ::: : .* : ::*:: * :: :. . ::* .:*: * *: .**:: *. *.: : : :. : :: *: . *: :. * : ::*. : . : ::: :: . : *.. :: *:. : : . * :. *:: *::: : :. : : . : . : :: *:* * * : :: : * ** .:::* **: :* ::: .* ..*: .:* : . :: * :*:: ....: ... * ..:*:: . :. : . : . : : * . : :.: : . .. : *: ... .. : . ..:: . * * .: ** .*. . * :* .. *: : * :::*:.* : : :. * :.: : *::: *: *:.**: * : . *.: .. . * . * . .: * .: : :: :: ", "identical_positions": 78, "similar_positions": 231, "identity": "7.49%" }, { "cls_id": "homologset.agr.HGNC:32206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "---------MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQPPEQSALPTAASYFAQNESEHNGGLADASSLQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQNQLRLEQLQQHCQDQQSTGEQQRQQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDESSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFKEASQVQPSKEETSEQKALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHENVELQRQQLMLQQQLDRLRHYEAKAYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHNHHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLPTAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLG-------VELPADAAQAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTEQPSHNHAGDHLNCCMGKFEVV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NDK9-1", "uniprot_id": "GOG6C_HUMAN", "id": "A6NDK9-1", "name": "Golgin subfamily A member 6C", "aln": "MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKS--PGIPAGAKTKKKKTDSSPETTTSG--------------GGHSPGDSQYQELAVALESSSVTIN-------------------------QLNENIESLKQQKKQVEHQLEEAKKTNN-------EIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVS-----------TQQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLS---ELKNQMAEPPSLAPP-AVTSVVEQLQDEAKHLRQEVEGLEGK---LQSQVENNQALSLLSKEQKQRLQEQEEMLREQE---------------------AQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKK-EERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEK-------LDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESRE-------------------------ATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKE-EEMKVKLLELQELVLPLVGNHEGHGKFLIAAQNPADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPAPGAAREGSPHDNPPVQQIVQLSPVMQDT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::: :*****:********* * * *.. :. .*:* ..*.: . ** : * . :: *:. :* .: * *** :: .:: :: * :*** : :: :::: :* .* : : *:*:: * ::: :. :.. ::* .:*: * *: :**:: ** * .:*.. ::. * * : :: *:* * *:*:. :*. : ::*.:* .** *: :** ::* .:*:*.::: :.:: ***.:. .*: *: *...: *. ** : *:** *::::*.:* : :* :::.:: *.:. :.*::* * *: :: :*.*. :::* * ::*: : : * ** .:* *: .:. .. *::** :*:*: ::*.: : .*.:: *.::* *.*: . :: : .::::.* *::.:* :* *..* .: .: ::: . : . ** *: * .:.: : . *.* : . * * * .: ** **: . * .:* .. *: : * :::*::* : : *. * :** * * *::: *: *::**:.* * * *.:* ..* : : * . :.::: : * * .: : . * . :: : *: ", "identical_positions": 156, "similar_positions": 263, "identity": "19.16%" }, { "cls_id": "homologset.agr.HGNC:32207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGG3-1", "uniprot_id": "A0ABK0LGG3_RAT", "id": "A0ABK0LGG3-1", "name": "", "aln": "------------------------------MMRSLNQGSSAPGGAGKG--EEPEKLPELAEDESQVLRGTGHCKWFNVRMGFGFISMISREGNPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSPKGLESIRVTGPGGNPCLGSERRPKGKT-LQKRKPKADRWRRQDLLMDQMWTVREEESRMIPRCYNCGGLD-HHAKECGLPPQPKKCHYCQSIMHMVANCPHKLVAQLPASAQGRPEAESQPCTSPSPREVGGGHGCTVP-FPQEVTSEMAEQSDRSPQEVSATKAFAAIGEQNKKGPLIQKRKKT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q45KJ6-1", "uniprot_id": "LN28B_MOUSE", "id": "Q45KJ6-1", "name": "Protein lin-28 homolog B", "aln": "---------------------------------------MAEGGASKG--EEPEKLPGLAEDEPQVLHGTGHCKWFNVRMGFGFISMISREGNPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSPKGLESIRVTGPGGSPCLGSERRPKGKT-LQKRKPKGD------------------------RCYNCGGLD-HHAKECSLPPQPKKCHYCQSIMHMVANCPHKLAAQLPASSQGRQEAESQPCSSAAPREVGGGHGCTVL-FPQEVKSEMAEHSDRSPQEVSSTKAFAAIGEQNKKGPLIQKRKKT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZN17-1", "uniprot_id": "LN28B_HUMAN", "id": "Q6ZN17-1", "name": "Protein lin-28 homolog B", "aln": "---------------------------------------MAEGGASKGGGEEPGKLPEPAEEESQVLRGTGHCKWFNVRMGFGFISMINREGSPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSSKGLESIRVTGPGGSPCLGSERRPKGKT-LQKRKPKGD------------------------RCYNCGGLD-HHAKECSLPPQPKKCHYCQSIMHMVANCPHKNVAQPPASSQGRQEAESQPCTSTLPREVGGGHGCTSPPFPQEARAEISERSGRSPQEASSTKSSIAPEEQSKKGPSVQKRKKT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T854-1", "uniprot_id": "A0AB32T854_DANRE", "id": "A0AB32T854-1", "name": "", "aln": "MNFTKIVGCFLRGFVLLSTSVWIRISTHHIQGQTRITNSMAVHSISGG--PRRGGGSDTARTPPQSLSGSGYCKWFNVRMGFGFISMTSSEGKPVDPPLDVFVHQSKLVMEGFRSLREGEQVEFTFKRSSKGLESLRVTGPGGGPCSGSERRPKAKAPPLKRKPKGD------------------------RCYNCGGLD-HHAKECGLPPQPKKCHYCQSVTHMVAQCPHKGAPSPSAS-----QDPQRPSTSAQ-----------------------------SPEEESRSGSSSSPEEASQRGSRSQRWRKSRD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRN5-1", "uniprot_id": "LIN28_DROME", "id": "Q9VRN5-1", "name": "Protein lin-28 homolog", "aln": "------------------------------MENVQLENGLERRTTSQSSTSSANPANLASPTEECGCVRLGKCKWFNVAKGWGFL-------TPNDGGQEVFVHQSVIQMSGFRSLGEQEEVEFECQRTSRGLEATRVSSRHGGSCQGSTYRPRINR--RTRR---------------------------MRCYNCGEFANHIASECALGPQPKRCHRCRGEDHLHADCPHKNVTQSHSN----------------------------------------------SKSISNNSSSSAAQEKSEEAT----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * ****** *:**: .* * :****** : *.***** * * *** :::.:***: **:. *..* ** **: : .*: ****** : * *.**.* ****:** *:. *: *:**** ... :. .:. * . : : * .:... ", "identical_positions": 67, "similar_positions": 47, "identity": "21.14%" }, { "cls_id": "homologset.agr.HGNC:3221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97553-1", "uniprot_id": "EFNA1_RAT", "id": "P97553-1", "name": "Ephrin-A1", "aln": "MEFLWAPLLGLCCSLAAADRHIVFWNSSNPKFREEDYTVHVQLNDYLDIICPHYEDDSVADAAMERYTLYMVEHQEYVTCEPQSKDQVRWKCNQPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIYHQETQCLKLKVTVNGKITHSPHAHANPQEKRLQADDPEVQVLHSIGHSAAPRLFPLVWAVLLLPLLLLQTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52793-1", "uniprot_id": "EFNA1_MOUSE", "id": "P52793-1", "name": "Ephrin-A1", "aln": "MEFLWAPLLGLCCSLAAADRHIVFWNSSNPKFREEDYTVHVQLNDYLDIICPHYEDDSVADAAMERYTLYMVEHQEYVACQPQSKDQVRWNCNRPSAKHGPEKLSEKFQRFTPFILGKEFKEGHSYYYISKPIYHQESQCLKLKVTVNGKITHNPQAHVNPQEKRLQADDPEVQVLHSIGYSAAPRLFPLVWAVLLLPLLLLQSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20827-1", "uniprot_id": "EFNA1_HUMAN", "id": "P20827-1", "name": "Ephrin-A1", "aln": "MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIGHSAAPRLFPLAWTVLLLPLLLLQTP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************* ***********:****:*******:*********.********:* **:***:** *:*********:**:******************** ******************:::* :**:*****.*****.*:** ******* ******:******:*********.*:**********: ", "identical_positions": 173, "similar_positions": 23, "identity": "84.39%" }, { "cls_id": "homologset.agr.HGNC:32213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1RLQ5-1", "uniprot_id": "DIK1A_DANRE", "id": "Q1RLQ5-1", "name": "Divergent protein kinase domain 1A", "aln": "----------------------------------------MARGLFSRAWLSKTHHFQARLSYIRVKYLFLTWLAVFVSSWVVYVQYSTYTELCRGRECKSIICDKYSKGIIDGSACSSLCEESKLYFGRCLSTKPNNQVYTGSWGDQDGVIKCQLSDVLHYELGEELEPKKEITLFEKPTRGTSVEKFKEMVASHLKAKVGEQANLSNLVSLILSVADSNKDGHISLPEAKSAWALLQLNEVLLAVVLQGREHTPKLLGFCGDLYVVERVPHAPLFGITLPWPMDLWIPAGMRRSMDQWFTPSWPRKAKIFIGLLELIEDIFHGTFGSFLMCDMRASSFGYTDRHDLRLVDGRRVVAEEAFKQAMILQRCKDHEDCVYGADCRTSCDLSEQRCTAEVAQPNLARACGAMKDYLLRGAPFHLQEELEKQLYACMALKGSAEQMEMEHSLILNNLKTLLWKQISHTTDS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FCF0-1", "uniprot_id": "E7FCF0_DANRE", "id": "E7FCF0-1", "name": "", "aln": "MLLIAREVRRLRSITLFIIRSPYGEKHPGLVSAVKCGVSIMARGLIPWIWLKRPVYIQARFSYLHMKFLFFSWLAVFVGSWVVYVEYSSYTELCRGHECKNTICDKFQKGVIDGSACNSLCEKDTLYLGKCLSAKPSNQVYSGSWGDMEGIIKCQMKEDPHYDLGFELEPRKESASFSRPTKGTSMQKFKEMVFNHLKAKVGDQANLADLLTLVLGVADSNKDGEISLSEAHSAWALLQLNEFLLSVVLQEREHTPRLLGFCGDLYVMEKVPYVPLYGVSLPWMVELWIPASLRRSIDQWATPSWPRKAKIAIGLFELVEDVFHGTFGSFLMCDVSAAGFGYTERHDIKVVDARQIVPEVGFQEVMRERRCEEDTDCLYGRDCFTSCDLTKHRCTTEVTQPNLAKVCSTLKDYILYGAPSDIKDELDKQLYACIALKGASEQMEMEHSLILNNLKTLLWKKISHTKDS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5T7M9-1", "uniprot_id": "DIK1A_HUMAN", "id": "Q5T7M9-1", "name": "Divergent protein kinase domain 1A", "aln": "----------------------------------------MARSLCPGAWLRKPYYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D6I7-1", "uniprot_id": "DIK1A_MOUSE", "id": "Q9D6I7-1", "name": "Divergent protein kinase domain 1A", "aln": "----------------------------------------MARSLCAGAWLRKPHYLQARLSYMRVKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSNKPSNQMYLGVWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDRDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVMELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNEKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDLSTMKCTSEVIQPNLAKACQLLKDYLLHGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.* . ** :. ::***:**:::*:**::**.***.**::**:**:*******::**. ****:..*:***.**.*** ..**:*:*** **.**:* * *.: *::***:.: * ::* ****:** . *.:**:**:::****** . :***:*:*.**::*:.*:* ***.::**.:** **:**********.** *:** :****:*:********:* * :..*:*::*** ::*:**:.:***:** ********** ***:*::**:***.:*.***** * .:**.:::*:::** *::*.* ::: : ::*:.. **:** ** **** : :**:** *****:.* :***:* *** .:::**:****:*:*** :::*******************:**:*.**", "identical_positions": 241, "similar_positions": 135, "identity": "51.5%" }, { "cls_id": "homologset.agr.HGNC:3222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA19-1", "uniprot_id": "F1MA19_RAT", "id": "F1MA19-1", "name": "", "aln": "MAPAQRPLLPLLLLLLPLR----ARNEDPARANADRYAVYWNRSNPRFQVSAVGDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMERYILYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNLVDRPCLRLKVYVRPTNETLYEAPEPIFTSNSSCSGLGGCHLFLTTVPVLWSLLGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52801-1", "uniprot_id": "EFNA2_MOUSE", "id": "P52801-1", "name": "Ephrin-A2", "aln": "MAPAQRPLLPLLLLLLPLR----ARNEDPARANADRYAVYWNRSNPRFQVSAVGDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMERYILYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNLVDRPCLRLKVYVRPTNETLYEAPEPIFTSNSSCSGLGGCHLFLTTVPVLWSLLGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43921-1", "uniprot_id": "EFNA2_HUMAN", "id": "O43921-1", "name": "Ephrin-A2", "aln": "MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79727-1", "uniprot_id": "EFNA2_DANRE", "id": "P79727-1", "name": "Ephrin-A2", "aln": "--------MELSLVVFTVVCWVSVWSDD--RIISDRHAVYWNSSNSRFWQ------GEYTVAVSINDYLDVYCPYYESPQP-HSRMERYILFMVNHDGYLTCEHRMRGFKRWECNRPQSPDGPLRFSEKFQLFTPFSLGFEFRPGHEYYYISSPHPNHAGKPCLKLKVYVKPT-SSGYESPEPFLTDQSQRCGADGPCLAVLMLLLVFLLAGV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *:::.: . :* * :**:***** **.** * *** ********:***:* :* * .***:*:*:*** :*: :*:** *********** :*.***:***************************:. ** ..:***:*****:** .: **:***::*.:.. .. .* * : : ::: * * ", "identical_positions": 109, "similar_positions": 49, "identity": "51.17%" }, { "cls_id": "homologset.agr.HGNC:32220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L4S1-1", "uniprot_id": "A0ABK0L4S1_RAT", "id": "A0ABK0L4S1-1", "name": "NADH-cytochrome b5 reductase-like", "aln": "-MAER-EDD-HAEAWLQLKPVEPLPSQCCGSGCSPCVFDLYYRDLERWDTAQAKNDMSLLSGKQPPESQGCSTKLSPETFLAFHISTMEKVTRDTYLVRFTLPGNCH-LGLLPGQHLILRGVVDD-LEIQRAYTPISPATAQGYFDVLIKCYETGLMSRYVESWRPGDTAFWRGPFGSFLYEPKKYGELLMLAAGTGLAPMVPIVQSITDNEDDETFVTLVGCFKTFEDIYLKTFFQEQARFWNVRTFFVLSQEVSP-----------DQLPWS-----YRDKTHFGRLG-QELVDELVARCRRRPFTLVCG---SPAFTEDMARCLLSAGLTEDSYFLF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AS42-1", "uniprot_id": "NB5R5_MOUSE", "id": "B1AS42-1", "name": "NADH-cytochrome b5 reductase-like", "aln": "-MAET-EEEEDSEAWLRLKPVEPLPSQCCGSGCSPCVFDLYYRDLERWETARARNDRSLLSGKQPPESQSCSAKLSPETFLAFHISTMEKVTKDTYLVRFTLPGNSR-LGLRPGQHLILRGVVDG-LEIQRAYTPISPVTAEGYFDVLIKCYRTGLMSQYVESWRTGDTAFWRGPFGSFLYEPKKYGELLMLAAGTGLAPMVPILQSITDDEDDETFVTLVGCFKTFEGIYLKTFFQEQARFWNVQTFFVLSQEVSP-----------EQLPWS-----YRDKTHFGRLG-QELVAELVACCRRKPFTLVCG---SPAFNEDMARCLLSAGLTEDSYFLF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IPT4-1", "uniprot_id": "NB5R5_HUMAN", "id": "Q6IPT4-1", "name": "NADH-cytochrome b5 reductase-like", "aln": "MMAEREEDDDTEEAWMQLRPTEPLPSQCCGSGCSPCVFDLYHRDLARWEAAQASKDRSLLRG---PESQSCPSKLNPETFVAFCIIAMDRLTKDTYRVRFALPGNSQ-LGLRPGQHLILRGIVDD-LEIQRAYTPISPANAEGYFEVLIKCYQMGLMSRYVESWRVGDTAFWRGPFGDFFYKPNQYGELLLLAAGTGLAPMVPILQSITDNENDETFVTLVGCFKTFESIYLKTFLQEQARFWNVRTFFVLSQESSS-----------EQLPWS-----YQEKTHFGHLG-QDLIKELVSCCRRKPFALVCG---SAEFTKDIARCLLCAGLTEDSYFLF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWK8-1", "uniprot_id": "Q9VWK8_DROME", "id": "Q9VWK8-1", "name": "FAD-binding FR-type domain-containing protein", "aln": "-MLSYLEDLKENEDQLRD-------SDCCGNGCTNCILDNKPRPSKRVLLAGKRN--VILSYTKFRLLRREALGPNGQLLLLHFAHAAEEGDGDG-------AVDTV-LDIPPGHHVMLR--VG---SLLRPYSPYWSDFVAKEFRILVKLQPEGPMSRHLQAVQPDDLLEFRGPIGQYVHEPQPAKCIYIIAQGVAIAPTLPLVRQVLDNEEDMSRLWHLVCAHDLLHVYFREEMLEFAQFWNYRSCLYLPHQQCDSSACQEAGHCAQQCPQLRDNLRYKETAKVSRLDATELATHLNPAIPGQRVLIVAG---DSSFQKNIAQIATQSLDVDPANIYML", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36060-1", "uniprot_id": "MCR1_YEAST", "id": "P36060-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "-MFSR--------------------LSRSHSKALPIALGTVAIAAATAFYFANRNQHSFVFN------ESNKVFKGDDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGSNVVRPYTPVSDLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQFKSITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPDKFNVTYFVDDKQ-----------DDQDFDGEISFISKDFIQEHVPGPKESTHLFVCGPPPFMNAYSGEKKSPKDQGELIGILNNLGYSKDQVFKF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . . . :. : :: . . : : :. * . : :.: . :: : . .: *.*:* * :::* * *: :: . : .* ::**: .: :*: : ::. *..: * : : : :: :* : : : : : :: : . : : . : :: . :: . .* . .* .. :: . : : ", "identical_positions": 18, "similar_positions": 88, "identity": "5.28%" }, { "cls_id": "homologset.agr.HGNC:32221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UZW7-1", "uniprot_id": "EF2KT_MOUSE", "id": "Q3UZW7-1", "name": "Protein-lysine N-methyltransferase EEF2KMT", "aln": "MAPEDHEGATSLLQSFERRFLAARALPSFPWQSLEEKLKDPSGSELLLAILQRTVKHPVCVQHGPSVKYARCFLSKLIK---KHEAVPTEPLDALYEALAEVLMTQ---ESTQCHRSYLLPSGNSVTLSESTAIVSHG-TTGLVTWDAALYLAEWAIEN-----------PAAFTDRTILELGSGAGLTGLAICKACCPRAY---IFSDCHAQVLEQLRGNVLLNGFSLEPHTPIDAGSSKVTVAQLDWDEVTASQLS-AFQADVVIAADVLYCWEMTLSLVRVLKMLEDCQRKS-APDVYVAYTIRSQDTGKLFIEELDRAGIYWEEVPPHTGKLFPYEEHSAIVILKLVLTSRHGV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8P8-1", "uniprot_id": "D3Z8P8_RAT", "id": "D3Z8P8-1", "name": "", "aln": "MAPEDHEGATSLLQSFERRFLAARALPSFPWQSLEEKLREPSGSELLLAILQKTVKHPVCVQHGPSLKYSRCFLSKLIK---KHEAVPMEPLDALYEALAEVLMAR---ESTQCHRSYLLPSGDSVTLSESTAIVSHG-TTGLVTWDAALYLAEWAIEN-----------PAAFTDRTILELGSGAGLTGLAICKACYPRAY---VFSDCHAQVLEQLRRNVLLNGFSLELHTPIDSGSPKVTVAQLDWDEVTSSQLS-AFQADTVIAADVLYCGEVTLSLVRVLRMLTDCQRKK-APDVYVAYTIRSQDTGKLFITELDRAGIHWEEVAPHTGKLFPYEEHSAIVILKLTLTGRHGV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96G04-1", "uniprot_id": "EF2KT_HUMAN", "id": "Q96G04-1", "name": "Protein-lysine N-methyltransferase EEF2KMT", "aln": "MAPEENAGTELLLQSFERRFLAARTLRSFPWQSLEAKLRDSSDSELLRDILHKTVKHPVCVKHPPSVKYARCFLSELIK---KHEAVHTEPLDELYEALAETLMAK---ESTQGHRSYLLPSGGSVTLSESTAIISYG-TTGLVTWDAALYLAEWAIEN-----------PAVFTNRTVLELGSGAGLTGLAICKMCRPRAY---IFSDCHSRVLEQLRGNVLLNGLSLEADITAKLDSPRVTVAQLDWDVATVHQLS-AFQPDVVIAADVLYCPEAIMSLVGVLRRLAACREHQRAPEVYVAFTVRNPETCQLFTTELGRAGIRWEVEPRHEQKLFPYEEHLEMAMLNLTL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N2S9-1", "uniprot_id": "A0A8M1N2S9_DANRE", "id": "A0A8M1N2S9-1", "name": "", "aln": "---MEHKTRKDIIHRFQVNFLAMSLLNTFPWDHLDEEIRNSNTSDIIEDILHKTCLHPICVKNPPSLKYRRRFLTELIK---RQEKLSAEPLDILYEALGEVMCAQ---EEDLCFKTYLLPTGDAVSLAENVALISQG-TTGLVTWEAALYLAEWTLEN-----------AHIFKNKTVLELGSGIGLTGIVLCRSCSLTKY---IFSDCHQTVLQRLKDNITN----------CLANCDGVSVEELDWENVSDEQLQ-RIQANTIIAADVVYDPDIIACLVRLLSRLLNCKVEENHPDVYVASTVRNPQTYECFKKELERAGLRHVIMKDSVTQVFPYNRASTIEMIKIYV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWJ9-1", "uniprot_id": "Q9VWJ9_DROME", "id": "Q9VWJ9-1", "name": "Protein-lysine N-methyltransferase EEF2KMT", "aln": "--------MSRKYGKLQQQFLCCYPVNKMAWSSVTLPLSWEDQ----QELLAATCGHPMNQCYPVRRSYLEAFLKHLLLLLGDQEDLHDDIYSSLCGPVAENEASTG--SSTYAYKHYLLEPGAHITLRESTSFVAEG-TTGLCTWEAALALGDYLLQH-----------RDLVRGKNIVELGAGAGLLGIMLKLPALQLQVGQVLLTDGSEPCVQLMRENISLN-------FPDTPKEQMPQAEQLNWAAVSEFPWDSHAKTDLLIAADVIYDDSQFDALLGAMDYLYSRRGGG--LETLLASTVRNVDTLHKFMTQLGDSGYKVTPCANVSACASHFCRDHTAAVQIISIRR---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47163-1", "uniprot_id": "EFM3_YEAST", "id": "P47163-1", "name": "Protein-lysine N-methyltransferase EFM3", "aln": "------MNEDLFYDRLHQRCPGKYLLEELETSKSNDVLH-ASRFVCEMELVQKTNAYYCKTIVKMLLDHEWIFAKAFTIV--NDGEDEIEIYDYLYEKYIKLLSTGKPDPMMKDVVRYRFDEDVKIKIEETPNLISAASTTGFRTWEAALYMGDFLIHKPLQELAPVQGQDDGKKKLNVLEVGAGTGIVSLVILQKYHEFVNKMYVTDGDSNLVETQLKRNFELN-------NEVRENEPDIKLQRLWWGSD-----RVPEDIDLVVGADVTYDPTILPDLCECLAECLALDRCK---LCLLSATIRSESTVQLFSQECNKLGLKCTIVTSTEYDANNEIRAMKALQFKPLIAPIRIYKITKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : . : . :: * : .: * . : . : . * : : * : . :.: *. ::: . ***: **:*** :.:: :.: .::*:*:* *: .: : : . :: *. .* * . : ::.*** * * : :: *:*. .* . * : * . : ", "identical_positions": 30, "similar_positions": 69, "identity": "8.26%" }, { "cls_id": "homologset.agr.HGNC:32222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UZW7-1", "uniprot_id": "EF2KT_MOUSE", "id": "Q3UZW7-1", "name": "Protein-lysine N-methyltransferase EEF2KMT", "aln": "MAPEDHEGATSLLQSFERRFLAARALPSFPWQSLEEKLKDPSGSELLLAILQRTVKHPVCVQHGPSVKYARCFLSKLIK---KHEAVPTEPLDALYEALAEVLMTQ---ESTQCHRSYLLPSGNSVTLSESTAIVSHG-TTGLVTWDAALYLAEWAIEN-----------PAAFTDRTILELGSGAGLTGLAICKACCPRAY---IFSDCHAQVLEQLRGNVLLNGFSLEPHTPIDAGSSKVTVAQLDWDEVTASQLS-AFQADVVIAADVLYCWEMTLSLVRVLKMLEDC-QRKSAPDVYVAYTIRSQDTGKLFIEELDRAGIYWEEVPPHTGKLFPYEEHSAIVILKLVLTSRHGV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8P8-1", "uniprot_id": "D3Z8P8_RAT", "id": "D3Z8P8-1", "name": "", "aln": "MAPEDHEGATSLLQSFERRFLAARALPSFPWQSLEEKLREPSGSELLLAILQKTVKHPVCVQHGPSLKYSRCFLSKLIK---KHEAVPMEPLDALYEALAEVLMAR---ESTQCHRSYLLPSGDSVTLSESTAIVSHG-TTGLVTWDAALYLAEWAIEN-----------PAAFTDRTILELGSGAGLTGLAICKACYPRAY---VFSDCHAQVLEQLRRNVLLNGFSLELHTPIDSGSPKVTVAQLDWDEVTSSQLS-AFQADTVIAADVLYCGEVTLSLVRVLRMLTDC-QRKKAPDVYVAYTIRSQDTGKLFITELDRAGIHWEEVAPHTGKLFPYEEHSAIVILKLTLTGRHGV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C5J1-1", "uniprot_id": "F86B2_HUMAN", "id": "P0C5J1-1", "name": "Putative protein N-methyltransferase FAM86B2", "aln": "MAPEENAGTELLLQGFERRFLAVRTLRSFPWQSLEAKLRDSSDSELLRDILQKTVRHPVCVKHPPSVKYAWCFLSELIK---KHEAVHTEPLDKLYEVLAETLMAK---ESTQGHRSYLLSSGGSVTLSKSTAIISHG-TTGLVTWDAALYLAEWAIEN-----------PAAFINRTVLELGSGAGLTGLAICKMCRPRAY---IFSDPHSRILEQLRGNVLLNGLSLEADITGNLDSPRVTVAQLDWDVAMVHQLS-AFQPDVVIAADVLYCPEAIVSLVGVLQRLAACREHKRAPEVYVAFTVRNPETCQLFTTELGRDGIRWEAEAHHDQKLFPYGEHLEMAMLNLTL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N2S9-1", "uniprot_id": "A0A8M1N2S9_DANRE", "id": "A0A8M1N2S9-1", "name": "", "aln": "---MEHKTRKDIIHRFQVNFLAMSLLNTFPWDHLDEEIRNSNTSDIIEDILHKTCLHPICVKNPPSLKYRRRFLTELIK---RQEKLSAEPLDILYEALGEVMCAQ---EEDLCFKTYLLPTGDAVSLAENVALISQG-TTGLVTWEAALYLAEWTLEN-----------AHIFKNKTVLELGSGIGLTGIVLCRSCSLTKY---IFSDCHQTVLQRLKDNITN----------CLANCDGVSVEELDWENVSDEQLQ-RIQANTIIAADVVYDPDIIACLVRLLSRLLNCKVEENHPDVYVASTVRNPQTYECFKKELERAGLRHVIMKDSVTQVFPYNRASTIEMIKIYV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWJ9-1", "uniprot_id": "Q9VWJ9_DROME", "id": "Q9VWJ9-1", "name": "Protein-lysine N-methyltransferase EEF2KMT", "aln": "--------MSRKYGKLQQQFLCCYPVNKMAWSSVTLPLSWEDQ----QELLAATCGHPMNQCYPVRRSYLEAFLKHLLLLLGDQEDLHDDIYSSLCGPVAENEASTG--SSTYAYKHYLLEPGAHITLRESTSFVAEG-TTGLCTWEAALALGDYLLQH-----------RDLVRGKNIVELGAGAGLLGIMLKLPALQLQVGQVLLTDGSEPCVQLMRENISLN-------FPDTPKEQMPQAEQLNWAAVSEFPWDSHAKTDLLIAADVIYDDSQFDALLGAMDYLYSR--RGGGLETLLASTVRNVDTLHKFMTQLGDSGYKVTPCANVSACASHFCRDHTAAVQIISIRR---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47163-1", "uniprot_id": "EFM3_YEAST", "id": "P47163-1", "name": "Protein-lysine N-methyltransferase EFM3", "aln": "------MNEDLFYDRLHQRCPGKYLLEELETSKSNDVLH-ASRFVCEMELVQKTNAYYCKTIVKMLLDHEWIFAKAFTIV--NDGEDEIEIYDYLYEKYIKLLSTGKPDPMMKDVVRYRFDEDVKIKIEETPNLISAASTTGFRTWEAALYMGDFLIHKPLQELAPVQGQDDGKKKLNVLEVGAGTGIVSLVILQKYHEFVNKMYVTDGDSNLVETQLKRNFELN-------NEVRENEPDIKLQRLWWGSD-----RVPEDIDLVVGADVTYDPTILPDLC---ECLAECLALDRCKLCLLSATIRSESTVQLFSQECNKLGLKCTIVTSTEYDANNEIRAMKALQFKPLIAPIRIYKITKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : . : . :: * : .: * . : . : . * : : * : . :.: :. ::: . ***: **:*** :.:: :.: .::*:*:* *: .: : : . :: *. .* * . : ::.*** * * * :: *:*. .* . * : * . : ", "identical_positions": 30, "similar_positions": 69, "identity": "8.26%" }, { "cls_id": "homologset.agr.HGNC:32224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PKN7-1", "uniprot_id": "INCA1_MOUSE", "id": "Q6PKN7-1", "name": "Protein INCA1", "aln": "MQGQEDGDSILPFAKCSRVVSRFSPCSLPPQNRRPMPQPYGDAFWENLSQRSSSNWMVEQYIPPILRATDCSRPSLHPLEGLPPPEKLWRRKRKKLHLERMQK-GPGSIPARVRAVTYHLEDLRRRQGIINELKRAQWGSSDATPELPAL-EEGFELLSTTKYFDVEEERATYPQKETYSVTP-RDQLLWTPWTPVGQQGTYASGQLSSLT-YSTATARKNPVYDPQAMELESEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GGY4-1", "uniprot_id": "A0A8I6GGY4_RAT", "id": "A0A8I6GGY4-1", "name": "", "aln": "MQGQEDGDSILPFAKCSRVVSRSSPCSLPSQKSRPMPQPYGEIFWENLSRRSNSNWMIEQYIPPILRATGCSQPGLHPLEGLPPPEKLWRRKGKKLHLERMQK-GLGSTPARVRAVTYHLEDLRRRQGIINELKKAQWGSSEATPELPVF-EEGCELLSTTKYLDVEEERATYPQGENYFVTP-RDQLLWSPWTPVGQQGTYASGQLNSLA-YSTVTARKNPIYSPQRMELESEE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VD86-1", "uniprot_id": "INCA1_HUMAN", "id": "Q0VD86-1", "name": "Protein INCA1", "aln": "MQVQDDGVNLIPFAKCSRVVSRSPPPRLPSQSLRPMPQRYGDVFWKNLNQRPTPTWLEEQHIPPMLRATGCSQLGLYPPEQLPPPEMLWRRKKRRPCLEGMQQQGLGGVPARVRAVTYHLEDLRRRQSIINELKKAQWGSSGAASEPVVLGEEGCGFPSTNEYPDLEEERATYPQEEDRFLTPGRAQLLWSPWSPLDQEEACASRQLHSLASFSTVTARRNPLHNPWGMELAASEE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:** .::*********** .* **.*. ***** **: **:**.:*....*: **:***:****.**: .*:* * ***** ***** :: ** **: * *. ******************.******:****** *:.* .: *** : **.:* *:********* * :** * ****:**:*:.*: : ** ** **: :**.***:**::.* *** :.* ", "identical_positions": 141, "similar_positions": 52, "identity": "59.75%" }, { "cls_id": "homologset.agr.HGNC:32225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W47-1", "uniprot_id": "WIPI2_MOUSE", "id": "Q80W47-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-------MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTED-------------VCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGS--------------------------------------------------------------------ASIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFS-MDGMFLSASSNTETVHIFKLEA----VREK--PPEEPTTWTGY--FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVG--ASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY57-1", "uniprot_id": "WIPI2_RAT", "id": "Q6AY57-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-------MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTED-------------VCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGS--------------------------------------------------------------------ATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFS-MDGMFLSASSNTETVHIFKLEA----VREK--PPEEPTTWTGY--FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVG--ASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLVTQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4P8-1", "uniprot_id": "WIPI2_HUMAN", "id": "Q9Y4P8-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-------MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVD-KLEQIYECTDTED-------------VCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGS--------------------------------------------------------------------ATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFS-MDGMFLSASSNTETVHIFKLET----VKEK--PPEEPTTWTGY--FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVG--AADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRL---------AYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P910-1", "uniprot_id": "A0A8M1P910_DANRE", "id": "A0A8M1P910-1", "name": "", "aln": "-------MNLASQSGEAGCSQLLFANFNQDNT------------------SLAVGTKSGYKFFSLSSVD-KLEQIYECTDTED-------------VCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPSGLCALSISNDNCYLAYPGS--------------------------------------------------------------------ATIGEVQVFDTVNLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFS-MEGLYLSASSNTETVHIFKLET----QREKSVPQEEPTTWTGY--FGKVLMASTTYLPAHVTEMFTQGRAFATVRLPFSGHKNICALAIIQKIPRLLVA--AADGYLYLYNLDPQEGGECTLMKQHKLDGSAEPANEILEQTAHDRPLVAQTYSAAVAKG--------------------YSEDQGAVGGAGVEDDMNTLHLDEENEQPPLILETD-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PER1-1", "uniprot_id": "M9PER1_DROME", "id": "M9PER1-1", "name": "", "aln": "------MMSLLGRTDVDAG--EVFVNFNQNIT------------------SLAVATSGGYSLYSLGSVDSTLDKIYH-TKSDE-------------LFLIERLFESSLVAIVSQR-----APRKLKVCHFKKQSEICNYSYANTILAVKLNRERLIVCLEES-LYIHNIQDMKVVHTIRDTPCNPQGLCALSSSSEHCYLAYPGS--------------------------------------------------------------------VTAGEVQIFDAINLHAKTMIPAHDTPLAALAFSPSGTEIATASERGTVIRVFSSQDGSRLFELRRGLKRCVSIVSLSFS-TCAEYLVSSSNTETVHIFRLDRSATETAEGHGSKQSSDDWMGYSFFRFLSKTVTSYLPTQVTDVFSQGRAFASVTLPEAGVRRMCAIATIQKQLRLLIA--SQDGYLYVYSIPTVEGAECQLIKRHDLRLEDHYAMDIKVDSPQTLGLNSGVSIGGAAGVPPSSASAAGAGTGG-----SGGDGKSAVSVTGGVDKPSSSYASAVKGDDPVGPSSA-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43601-1", "uniprot_id": "ATG18_YEAST", "id": "P43601-1", "name": "Autophagy-related protein 18", "aln": "--------------MSDSSPTINFINFNQTGT------------------CISLGTSKGFKIFNCEPFG-----KFYSEDSGG-------------YAIVEMLFSTSLLALVGIGDQPALSPRRLRIINTKKHSIICEVTFPTSILSVKMNKSRLVVLLQEQ-IYIYDINTMRLLHTIETNP-NPRGLMAMSPSVANSYLVYPSPPKVINSEIKAHATTNNITLSVGGNTETSFKRDQQDAGHSDISDLDQYSSFTKRDDADPTSSNGGNSSIIKNGDVIVFNLETLQPTMVIEAHKGEIAAMAISFDGTLMATASDKGTIIRVFDIETGDKIYQFRRGTY-ATRIYSISFS-EDSQYLAVTGSSKTVHIFKLGHS---MSNNKLDSDDSN-------MEEAAADDSSLDTTSIDALSDEENPTRLAREPYVDASRKTMGRMIRYSSQKLSR--RAARTLGQIFPIKVTSLLESSRHFASLKLPVETNSHVMTISSIGSPIDIDTSEYPELFETGNSASTESYHEP--------VMKMVPIRVVSSDGYLYNFVMDPERGGDCLILSQYSILMD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q02887-1", "uniprot_id": "ATG21_YEAST", "id": "Q02887-1", "name": "Autophagy-related protein 21", "aln": "MKVLQFNQDATCCVVAASSHQISIFNCDPFGKCFEIDTKNSKKKTSNNNGSASNSESRNNEESILITNGSRDRTDAEEEEDNEDNALVTGNILKEGEFVIEMLFSTSLIAIADRG-QGLNKGKKLKIVNTKRKCTICEIVFPHEIVDVVMNRKRMCVLLESDQIFIYDISCMKPLETIDLWEDHYKRSQANSFSNASNTGTLEGDSAN-----------------------------------------------------------------LNRVATNLLANATQKSVNGSNPSVRTRRNSLRSKIRPRMVLSNDDRSILCFTAYSSPKKNKPNSEALYDVVIYDTLNVTPVNYLNSVHKGNVACLAVSHDGKLLATASDKGTIIRVFHTGVDSDYMSSRSLFKEFRRGTRLCNLYQLAFDKSMTMIGCVGDTDTIHLFKLDDASNSLPGDNSSNGHWNEEEYILASNSNPSMGTPKEIPLSKPRIANYFS-KKIKSSIPNQNLSRNFAYITVNESNRSCLG---------FPDEFPNQVYIASDDGTFSIYSIPSKPGECVLTKNNKFT--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : . . : . . . . . . . ::* **.:**:*:.. ::*:: : *: **: :. *: * :*:.*: * *:.. ::*::* *: :.** : * * . . . . . :: . :. . . . :. :.: ::: . .: .. . :: .: ... : : : : : : : : . . : . * . : . : . : ", "identical_positions": 25, "similar_positions": 98, "identity": "4.36%" }, { "cls_id": "homologset.agr.HGNC:3223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52797-1", "uniprot_id": "EFNA3_HUMAN", "id": "P52797-1", "name": "Ephrin-A3", "aln": "-------MAAAPLLLLLLLVPVPLLP------------------------LLAQG----PGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTFLAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08545-1", "uniprot_id": "EFNA3_MOUSE", "id": "O08545-1", "name": "Ephrin-A3", "aln": "-------MAAAPLLLLLLLVPVPLLP------------------------LLAQG----PGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSS--------GPGGGAEQYVLYMVNLSGYRTCNASQGSKRWECNRQHASHSPIKFSEKFQRYSAFSLGYEFHAGQEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTLLAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LV88-1", "uniprot_id": "A0ABK0LV88_RAT", "id": "A0ABK0LV88-1", "name": "Ephrin-A3", "aln": "MQGRILGWAQVPGLGSCKLMPSDCRPSGQASPLFFCFLPHSRGPRYFQYRLKALGGPTTPGSTHEKSSRCVQRHSSKSLRREGYTVQVNVNDYLDIYCPHYNSS--------GPGGGAEQYVLYMVNLSGYRTCNASQGSKRWECNRQHASHSPIKFSEKFQRYSAFSLGYEFHAGQEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTLLAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1Q1X6-1", "uniprot_id": "A0A8M1Q1X6_DANRE", "id": "A0A8M1Q1X6-1", "name": "Ephrin-A3", "aln": "-----MALAAVS-LYLLALAWTNLRP--------------------------VHG---------NNRHAVYWNSSNIHLRREGYTVQVSVNDYLDIYCPHYNQSQ----RGSLERGVAEQYVLYMVSYRGYRTCDPQMGFKRWECNRPHAPHAPIKFSEKFQRYSAFSLGYEFNVGHEYYYISTPIHHHGHSCLRLRVYVCCSTVSNSDDDSSP--PDYTVRP--KLHDIDEF---NPEIPKLEKSVSGSSPSGDRLLITV-ATLLLAALLVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. * * * . * : . *. **********.*************.* * *********. *****:.. * ******* **.*:********************:.*:******** *: .***::*:***::.*:*.:.. * *::*: * *:: :::* **::******:**:**. ::* ::* :::* ::*.*", "identical_positions": 118, "similar_positions": 53, "identity": "43.22%" }, { "cls_id": "homologset.agr.HGNC:32233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3I2-1", "uniprot_id": "D4A3I2_RAT", "id": "D4A3I2-1", "name": "", "aln": "MLSRRRVFAVEQLGGRDGAFEDLAQGCVVPGVTCTYRRIPDKTHGCSLDFREGRSELRGLERQMPLLKLASQDSGMEMVVGDSSLATLSGLSQDSLNLEPMGSPELPPAPLDRLLARRKLEQVLERSREFP----SLSGRHGSLQLQNKPVGGVSIFVGEQESTEADTELEASLEEAKEVGSMESGASTCLPGQGLRYLEHLCLVLEQMARLQQLYLQLQTQRPSRDPEEEE--LAPVLSSSHIPDNRVQGHREELSQTKDP-GAEAASLPQVGVLVDSPSSLPEALLEPTHILPPSQEHK-DLSHWDKVKVLLNRIRWRSPRLPEPPVPPDSSGPSLTFLCFSIGWSSGISLKGLQAIPNGRSLFQHWSLRSHEQKIFLYDLLAPEWRGFAKKSLTFWLTAASLHCQEKRLVLSPLHGEGQVLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66JV7-1", "uniprot_id": "CH058_MOUSE", "id": "Q66JV7-1", "name": "Uncharacterized protein C8orf58 homolog", "aln": "MLSRRRVFAVERLGGRDGAFEDLAQGCVVPGVTCTYRRIPDNTHECSLDFREGQNELRGLERQMPLLKLASQDSGMEMVVGDSSLATLSGLSQDSLNLEPMGSPELPPAQLDRLLARQKLEEVLERSREFP----SLSAQRGPLQLLNKPVDGVPIFAGEQESTEADTELEAGLEEAKEVGNMESAACTCLPGQGLRYLEHLCLVLEQMVRLQQLYLQLQTQRPSRDPEEEV--LAPALSSSHIPDNRVQEHREELSQTKDPEGAEAASLPEVGVLVTSPSRLPEALLEPTHILPPSQEPK-DLSHWDKVKVLLNRLRWRSPRLPEPPVPPDGSGSRMEFRNLS-----------------------DRTPCHSQRKTFIPALVVKKPR---AKNLSV---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NAV2-1", "uniprot_id": "CH058_HUMAN", "id": "Q8NAV2-1", "name": "Uncharacterized protein C8orf58", "aln": "MMGRRRAFAVD---GRDGAGEGLARGCIVPGVTSTYRRIPDAAHGCSS--WERGDKFRGVGREALFLKLASRDSGVEMAVGDSPLAALPGLSQDSLDFESSGSSE-PPAQVGRLLASQKLGEVLERSRRLPTAPTSLSGQHRSLRLASKPEREVPLGAGQQESMEADTDLEAGLEEE-AVGGLGPGAWACLPGQGLRYLEHLCLVLEQMARLQQLYLQLRIQRPPGDPGEEESTRAPLPSPLHTPGNRGQGPWELLSQTEHT-GAKAASPPKVEVPSANPPRLPETPVEPTYHLPSSQGHKRDISHWDKVKVLLNRICRRSHHHPEPPAPPDGSDPRIESRDLP-----------------------ERPQCRPHRKTFMPSLVVKKQR---AKNLSVG--------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.***.***: ***** *.**:**:*****.******* :* ** * .::**: *: :*****:***:**.****.**:*.*******::*. **.* *** :.**** :** :******.:* ***.:: .*:* .** *.: .*:*** ****:***.*** **.: ..* :********************.*********: ***. ** ** ** *. * *.** * * ****:.. **:*** *:* * .*. ***: :***: **.** * *:************: ** : ****.***.*.. : :. . . .:* *: *:. : * *.*:. ", "identical_positions": 203, "similar_positions": 85, "identity": "47.76%" }, { "cls_id": "homologset.agr.HGNC:32235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0VG62-2", "uniprot_id": "RBIS_MOUSE", "id": "Q0VG62-2", "name": "Ribosomal biogenesis factor", "aln": "MAKNKLKGQKSRNVFHIASHKTFKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELK---HHENEPANVDEATRLMAQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AMX9-1", "uniprot_id": "A0A8I6AMX9_RAT", "id": "A0A8I6AMX9-1", "name": "", "aln": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKEL----HHEKEPANVDEATRLMAQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N0T1-1", "uniprot_id": "RBIS_HUMAN", "id": "Q8N0T1-1", "name": "Ribosomal biogenesis factor", "aln": "MAKNKLRGPKSRNVFHIASQKNFKAKNKAKPVTTNLKKINIMNEEKVNRVNKAFVNVQKELAHFAKSISLEPLQKELIPQQRHESKPVNVDEATRLMALL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:* **********:* :********************.*****:*:****:*****:*:**:**:.:**** :**.:*.********** *", "identical_positions": 76, "similar_positions": 17, "identity": "76.0%" }, { "cls_id": "homologset.agr.HGNC:32237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8WCG0-1", "uniprot_id": "SERC4_RAT", "id": "A8WCG0-1", "name": "Serine incorporator 4", "aln": "-MGAKDITGRSTTQGFAQQHGGVSDVVVKTPFYQVSCCGPVSWTSGCHS----LTESTCSRLFYILLHMGASAICCLLLSKTVVERVWGKAHGIQMPSVLCAHLFGNSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTSPRAQLHNSFWSLKLLFLLGLCTAAFCIPDEHLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQDCS----WFLGVLLATLGFYSMAGVGAVLLFHHYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRLRQPNSGLLQASIISCYIMYLTFSALSSRPPETIIFQGQ--NHTLCLPGQNKMEPQIPDASVAVFSASIMYACVLFACNEASYLAQLFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQGS-RARPADQETPPAAQVQSQHLS---YSYSGFHFAFFLASLYVMVTLTNWFSYEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAHHSESPPP--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XK03-1", "uniprot_id": "SERC4_MOUSE", "id": "Q5XK03-1", "name": "Serine incorporator 4", "aln": "MMGAKVVTGRSTTQGLAQQHGGVSN-VVETPFNQASCCGPVSWTSGCHS----LTESRCSRLLYILLHVGASAICCLLLSKTVVERVWGKAHGIQMPSVLCAHLFGSSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTNPRAQLHNSFWSLKLLFLLGLCVVAFCIPDEDLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQDCS----WLLGVSLATLGFYSMAGVGAVLLFHQYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRRKQPNSGLLQASIISCYIMYLTFSALSSRPPETITFQGQ--NHTLCLPGRNKMEPQIPDTSVAVFSAGIMYACVLFACNEASYLAELFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQRS-RARSADQETPPAAQVQSQHLS---YSYSGFHFAFFLASLYVMVTLTNWFSYEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAPHSESPPP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NH21-1", "uniprot_id": "SERC4_HUMAN", "id": "A6NH21-1", "name": "Serine incorporator 4", "aln": "MVGAKAGPSPGTSLGLAQQHSGGSSVLVKSPFCQVCCCGPAPCASCCHSRWPSLTASTCSRLFYILLHVGASAICCLLLSRTVVERVWGKTHRIQMPSGLCAHLFGLSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVHLHSPTSPRAQLHNSFWLLKLLFLLGLCAIAFCIPDEHLFPAWHYIGICGGFAFILLQLVLITAFAHSWNKNWQTGAAQDCS----WFLAVLLATLGFYSMAGVGAVLLFHYYTHPAGCLLNKMLLSLHLCFCGLISFLSIAPCIRLKQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQGQ--NHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAEVFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLS---YNYSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F5D2-1", "uniprot_id": "E7F5D2_DANRE", "id": "E7F5D2-1", "name": "", "aln": "-----------MSTAQALHHSGVYNYFLNMVAYQICCCCGPAPCSLCCSFCPPVKSSTSTRIMYTLFHILACTVSCLMLSKTVSEAVR---ENVPFFNVVCDEAHGGGDCQMLVGYSAVYRVCFGTACFYLMMAIFLIDVKSSQDFRALIHNGFWFLKFITMLGMIAAAFFIPTESFLHAWHYVGVVGGFSFILIQLILITAFAHTWNKNWLTGAAENKR----WYVAVMCATLFFYTIATMAFTFMYKYYTHPAGCHLNKALLWTNLALCTIMSFIAITPCVQQKKPRSGILQASIICCYVMYLTFSALSSRPPEKVEYQGV--NITICYPKVSRDEIQNEGNAVAIMGAAIMYCCVLFACNEASYLAEVFGPFWMIKVYRYEFQKASCCFCCPEAEDEEE-----FVIDENKGCQKVVHNETQRVA---YSYFFFHFVFFLASLYVMMTLTNWFSYETAVLETTFTHGSYSTFWVKLSSCWACVVLYLWLLLGPLCQCQSDPKRPRRARIKR-RIAAHRHVSVSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12116-1", "uniprot_id": "TMS1_YEAST", "id": "Q12116-1", "name": "Membrane protein TMS1", "aln": "-------------MGAVISLPVSMAGSFVASCFGGCCSNLVTKTASSLG-----SSSLGTRLLYAVWLLLNSLISWVSYSAN---------KSILWPGKTCT---GTGECGFFT----VHRLNFALGCLHLILALVLTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPNDFYIFFSKWVSVPSGAIFILVGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMFCHQQ-CNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSSEPDDKMCNPLVRSSGTRKFSIILGSLFTFIAIAYTTTRAAANSAFQGTNTNGAIYLGNDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLGTSSPTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGR-TYFYSWVKIVSAWICYALYGWTVVAPAIMPDRFDYENYY------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .*. . : . . . * :*::* : : . :. : * . . : . * * .:* .: *:*: . . ::*: *:.* ::*. . ** ::*.:* **:: * : . :* ** : : :::.: .* ***: *:*:. **: * :. : . .: * : .* :*: : : ..:: : * * :*: : :* : : .::: * :: :*.**: *:*::. * ***:**:**.* : : . * . : : *. . * * **.: : : ::: : . : :. .. : :. : *.* **. ****: :: : ** .: : . .. : :: ***: *.* * ** ::.* ", "identical_positions": 80, "similar_positions": 147, "identity": "15.18%" }, { "cls_id": "homologset.agr.HGNC:3224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEN1-1", "uniprot_id": "D3ZEN1_RAT", "id": "D3ZEN1-1", "name": "Ephrin-A4", "aln": "MRLLPLLRTVLWAALLG--SRLRGCSSLRHSIYWNSTNPRLLRGDAVVELGLNDYLDIFCPHYESPGPP-EGPETFALYIVDWSGYEACKAEGANAFQRWNCTLPFAPFVPVRFSEKIQRFTPFPLGFEFLPGETYYYISVPTPESPGQ-CLRLQVSVCCKEDRS--ESAHPVGSPGESGTSGWRGGHAPSPLSLLLLLLLPILRLLRVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08542-1", "uniprot_id": "EFNA4_MOUSE", "id": "O08542-1", "name": "Ephrin-A4", "aln": "MRLLPLLRTVLWAALLG--SRLPGCSSLRHPIYWNSSNPRLLRGDAVVELGFNDYLDIFCPHYESPGPP-EGPETFALYMVDWSGYEACTAEGANAFQRWNCSMPFAPFSPVRFSEKIQRYTPFPLGFEFLPGETYYYISVPTPESPGR-CLRLQVSVCCKESGSSHESAHPVGSPGESGTSGWRGGHAPSPLCLLLLLLLPILRLLRVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52798-1", "uniprot_id": "EFNA4_HUMAN", "id": "P52798-1", "name": "Ephrin-A4", "aln": "MRLLPLLRTVLWAAFLG--SPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPP-EGPETFALYMVDWPGYESCQAEGPRAYKRWVCSLPFG---HVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQ-CLRLQVSVCCKERKS--ESAHPVGSPGESGTSGWRGGDTPSPLCLLLLLLLLILRLLRIL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7R4-1", "uniprot_id": "A0A8M1Q7R4_DANRE", "id": "A0A8M1Q7R4-1", "name": "Ephrin-A4", "aln": "MNTPRCSGVCAMMRLLALFIHVLSTTAKRHVVYWNSTNTRLTGDDYSVQVNLSDYLDILCPHYPGDHPSGASVETLALYLVAESQFRGCVDT-KEAIKRWECNQPFAPFGPVRFSEKIQRFTPFSLGFEFLPGHHYYYSSLSTDDGPPLPCMKLRVTVCCP--------PTTAGSSRQEATETPSHSTTVQNMTLTQLFLLLIPFLLSYFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . :*. : . :: ** :****:*.** .* *::.:.*****.**** . *. . **:***:* . :..* .* :** *. **. *:*******:***.********. *** *:.* :.. *::*:*:*** . ..**. :..*. . : . : * *:** * ** : ", "identical_positions": 76, "similar_positions": 58, "identity": "36.02%" }, { "cls_id": "homologset.agr.HGNC:32249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYA6-1", "uniprot_id": "A0ABK0LYA6_RAT", "id": "A0ABK0LYA6-1", "name": "", "aln": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UW31-1", "uniprot_id": "PATE2_MOUSE", "id": "Q3UW31-1", "name": "Prostate and testis expressed protein 2", "aln": "MFVLVM------ICLFCQYWG-VLNELEEEDRGLLCYKCKKYHLGLCYGIMTSCVPNHRQTCAAENFYILTKKGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSNYCNLPMGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UY27-1", "uniprot_id": "PATE2_HUMAN", "id": "Q6UY27-1", "name": "Prostate and testis expressed protein 2", "aln": "MLVLFLLG---TVFLLCPYWGELHDPIKATE--IMCYECKKYHLGLCYGVMTSCSLKHKQSCAVENFYILTRKGQSMYHYSKLSCMTSCEDINFLGFTKRVELICCDHSNYCNLPEGV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . * * . :: : :**:***********:* ** :*:*:**.*******.:********:*****.*******.* :*.*****.**.***** *:", "identical_positions": 65, "similar_positions": 23, "identity": "55.08%" }, { "cls_id": "homologset.agr.HGNC:3225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52803-1", "uniprot_id": "EFNA5_HUMAN", "id": "P52803-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97605-1", "uniprot_id": "EFNA5_RAT", "id": "P97605-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVRDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08543-1", "uniprot_id": "EFNA5_MOUSE", "id": "O08543-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ39-1", "uniprot_id": "A0A8M1PZ39_DANRE", "id": "A0A8M1PZ39-1", "name": "EPH-related receptor tyrosine kinase ligand 7", "aln": "MPQVEMFYLLFSSLWMSVLGLDPASKVVADRYAVFWNRTNPRFYRGDYHIDVCINDYLDVYCPHYMDTVPEERTERYVLYMVNYDGYSSCDHTAKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYYYISSTLAENGRRSCLRLKVFVRPTNNCDKS---HDRVDKFDDRSINSIENNNDGTSHESAEPSRSDVNSAGRVQTVGPLLASVLVLLASLSSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :***: *:* ***.*:. **.**.*******:** :**** ****************:**** *:***::**********:****:****:******************************************:****::.:*******:*********.* *: :*** ..:*: **:* :* * ********. *:* : . *** :*.*** * :*", "identical_positions": 161, "similar_positions": 39, "identity": "70.0%" }, { "cls_id": "homologset.agr.HGNC:32250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCR--------PKGLQKLSQAARQRCDEQQRKAPFQKFPTEL--------QWRNQQGTLAQPQMSIIPGYRKMSEPPVEMALGKPTGPEKP----ALQSLDGP--FILHSRQKEGHNMTVPGVAKPVFRQDGRKTVSENLLDQKVQDISHQH-PVAVPKRKSITELFHKESKTQGPSKK---MQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIE---------SGQALRMIFTKHSHNFWSSRFLTVPAPLPIEKQ-TPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSS-EDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A4E2-1", "uniprot_id": "A2A4E2_MOUSE", "id": "A2A4E2-1", "name": "", "aln": "--MESQIKG--LPAVPAQTAQGEPRSSWEQTLPSLKKENHMVKCRNCGGFGHNVRSRMCPMKQGHVLLVSQPLGARKEKENGDPCR--------PHGLQKLSQDTRQRFDEQQRKAPFQKFPMKP--------QKGDQQVNLAQPRMPSIPGIRKRSASPVKTSLGKQMCPGKP----VLQCFDSS--YILHSRQKEGRRMAVAGVAKLVLRQDGRNSASEELLDQK--GTSCQH-PVAVPKSNASSELFHKEPKAQGPSRK---TQPSQHPVIHQNRQNPKLSFGAPGKEASWCPTQPSQNPLKKQRLNSTDAPEKSHARTGSKGTLDSQSPPIANRLGLKGANEMSKKITAQDPSTDQQQLYSRAALFATRPCIEFHRASAGRVADQALRMIFTRHGSNCWSSRFLSVPPPLPLEKQ-TPPSESPTFPEEGEVAGSQVKVSILYEDLQVSSSSSENSDGE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q658T7-1", "uniprot_id": "F90A2_HUMAN", "id": "Q658T7-1", "name": "Putative protein FAM90A2P", "aln": "MTARRDPKPGAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCRALGHTVRSTRCPMKCWKAALVPPTLGKKEGKENLKPWKPQVEANPGPLNKDKGEKEERPRQQDPQRKALLHIFSGKPPEKLLPNRKGSTESSVFLRVASRPMPVHTTSKRPCVDPELADRSATEMSGRGSVLASLSPLRKASLRSSSSLGPKERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSREGGCREVPQAASKTHGLLQAVRPQAQDKRPAVTQPGPPAATHSLGLGSNLSFRPGAKRPAQAPIQGCLNFPKKPRLGPFQIPESAIQGGELGALENLQPPPAATELGPSTSPQMGRRTPAQVPGVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENRRWSSSLLAAPSFHSPEKLGVFLAQSPHVSEKSEGPCVRVPPNVLYEDLQVSSSS-EDSDSDLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . * * * : :. *. .:*: :**::* .:** .*. **:* : **. .** :: *** .* : * . :* .: * * :: **** :: *. : : :. : : :* . . . *. *.. . . .* .:. *:* .. * . .*.* : : *: .* ** * * : **: : :. : : :.*. .:: **. .. *. ..:*** . :. : .* * * ** *:.. : **.: . : *. * *..* . : :*.:: ..* *..*:* :.*..* :::.* . *.**::* : . *** :*:.*. . ** . :** ..*:.* . :* .:*********** *:**.: ", "identical_positions": 106, "similar_positions": 142, "identity": "22.84%" }, { "cls_id": "homologset.agr.HGNC:32253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKP-------ALQSLDGPFILHSR---QKEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MXJ8-1", "uniprot_id": "F90A5_HUMAN", "id": "A8MXJ8-1", "name": "Protein FAM90A5", "aln": "MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRVDPVLADGSATEMSDRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: . . :* : . ..* *: .*.. :..* . :*..* . : * ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 131, "similar_positions": 155, "identity": "28.23%" }, { "cls_id": "homologset.agr.HGNC:32255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKGLQKLSQAARQRCDEQQRKAP-----------FQKFPTELQWRNQQGTLAQPQMSIIPG-----YRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NKC0-1", "uniprot_id": "F90A7_HUMAN", "id": "A6NKC0-1", "name": "Protein FAM90A7", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRSPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRAEANPGPLNKDKGEKEERPRQQDPQRNALLHMFSGKPPEKPLPNGKGSTESSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAVRPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELRAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHPAAGHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :*:. : . ::: ::::* *. *.* * :*: ..: :.. : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*.**::* : : : ... :. .:: * *..* :.: : .: ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: ::. ::*. * *..* . : :*.:: ..****.*:* *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 122, "similar_positions": 163, "identity": "26.29%" }, { "cls_id": "homologset.agr.HGNC:32256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKG--------LQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NJQ4-1", "uniprot_id": "F90A8_HUMAN", "id": "A6NJQ4-1", "name": "Protein FAM90A8", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPSAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSIDRQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. : ** .*****:**::****** **. ***:* : **. .** *: *** .* :*:* :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..**** *:* *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 130, "similar_positions": 156, "identity": "28.02%" }, { "cls_id": "homologset.agr.HGNC:32257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNJ1-1", "uniprot_id": "F90A9_HUMAN", "id": "A6NNJ1-1", "name": "Protein FAM90A9", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGTFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ... :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** * *** ..*:.**. :* *****************.: ", "identical_positions": 130, "similar_positions": 155, "identity": "28.02%" }, { "cls_id": "homologset.agr.HGNC:32258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKG--------LQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQPQMSIIPG-----YRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NDY2-1", "uniprot_id": "F90AA_HUMAN", "id": "A6NDY2-1", "name": "Protein FAM90A10", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTTCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDWQPPHSTPCLPTAQACTMSHHPAAGHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. **:* : **. .** *: *** .* :*:* :* .: * * :: **** :: * *.* * :*: ..: :.. : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*.**::* : : : ... :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.* * *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 128, "similar_positions": 156, "identity": "27.59%" }, { "cls_id": "homologset.agr.HGNC:3226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52796-1", "uniprot_id": "EFNB1_RAT", "id": "P52796-1", "name": "Ephrin-B1", "aln": "MARPGQRWLSKWLVAMVVLTLCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNKPQQEIRFTIKFQEFSPNYMGLEFKKYHDYYITSTSNGSLEGLENREGGVCRTRTMKIVMKVGQDPNAVTPEQLTTSRPSKESDNTVKTATQAPG-RGSQGDSDGKHETVNQQEKSGPGAGGSGSGDTDSFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGDSGTAGTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52795-1", "uniprot_id": "EFNB1_MOUSE", "id": "P52795-1", "name": "Ephrin-B1", "aln": "MARPGQRWLSKWLVAMVVLTLCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNKPHQEIRFTIKFQEFSPNYMGLEFKKYHDYYITSTSNGSLEGLENREGGVCRTRTMKIVMKVGQDPNAVTPEQLTTSRPSKESDNTVKTATQAPG-RGSQGDSDGKHETVNQEEKSGPGAGGGGSGDSDSFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98172-1", "uniprot_id": "EFNB1_HUMAN", "id": "P98172-1", "name": "Ephrin-B1", "aln": "MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********.******** :**********************************************************************************:*.***********************:*******************************:***********************:***** ****** *** ************:*******.*..***.*.**********************************************************.*******************************************************", "identical_positions": 328, "similar_positions": 14, "identity": "94.8%" }, { "cls_id": "homologset.agr.HGNC:32260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKGLQKLS--------QAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MX19-1", "uniprot_id": "F90AC_HUMAN", "id": "A8MX19-1", "name": "Protein FAM90A12", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRAEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDYLRVASGPMPVHTSSKRPRLDPILADRSATAMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHEGREPLLVVKPTHSRPEGGCREVPQAASKTHGLPQAARPQAQDKRPAVTSLPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :*:. : . : * * :: **** :: * *.* * :*: .. . :* : . ..* :: *.. :.. .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.:.: : ::: : *: . *. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 126, "similar_positions": 158, "identity": "27.16%" }, { "cls_id": "homologset.agr.HGNC:32261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKG--------LQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7W8-1", "uniprot_id": "F90AD_HUMAN", "id": "P0C7W8-1", "name": "Protein FAM90A13", "aln": "MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :*:* :* .: * * :: **** :: * *.* * :*: . . :* : . ..* :: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 129, "similar_positions": 157, "identity": "27.8%" }, { "cls_id": "homologset.agr.HGNC:32262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7W9-1", "uniprot_id": "F90AE_HUMAN", "id": "P0C7W9-1", "name": "Protein FAM90A14", "aln": "MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGDCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: . . :* : . ..* :: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 128, "similar_positions": 157, "identity": "27.59%" }, { "cls_id": "homologset.agr.HGNC:32263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7V4-1", "uniprot_id": "F90AF_HUMAN", "id": "P0C7V4-1", "name": "Protein FAM90A15", "aln": "MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: . . :* : . ..* :: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 128, "similar_positions": 157, "identity": "27.59%" }, { "cls_id": "homologset.agr.HGNC:32264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DV73-1", "uniprot_id": "F90AG_HUMAN", "id": "P0DV73-1", "name": "Protein FAM90A16", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 129, "similar_positions": 156, "identity": "27.8%" }, { "cls_id": "homologset.agr.HGNC:32265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DV74-1", "uniprot_id": "F90AH_HUMAN", "id": "P0DV74-1", "name": "Protein FAM90A17", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 129, "similar_positions": 156, "identity": "27.8%" }, { "cls_id": "homologset.agr.HGNC:32266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DV75-1", "uniprot_id": "F90AI_HUMAN", "id": "P0DV75-1", "name": "Protein FAM90A18", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLKFPKKPRLGPFQIPESAIQGGELGAPGNLQPPPAATELGPSTSPQMGRRTPAQVPSVDWQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ... :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. : ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.* * *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 128, "similar_positions": 156, "identity": "27.59%" }, { "cls_id": "homologset.agr.HGNC:32267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DV76-1", "uniprot_id": "F90AJ_HUMAN", "id": "P0DV76-1", "name": "Protein FAM90A19", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLKFPKKPRLGPFQIPESAIQGGELGAPGNLQPPPAATELGPSTSPQMGRRTPAQVPSVDWQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* *: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ... :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. : ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.* * *. ..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 128, "similar_positions": 156, "identity": "27.59%" }, { "cls_id": "homologset.agr.HGNC:32268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRP--------KGLQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDG------PFILHSRQKEGHNMTVPGVAKPVFRQDGRKTVSENLLDQKVQDIS-----HQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NIJ5-1", "uniprot_id": "F90AK_HUMAN", "id": "A6NIJ5-1", "name": "Protein FAM90A20", "aln": "MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPGVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDYLRVARGPMPVHTTCKRPRMDPVLSGRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPRPAVRHQVHETLLVVEPTHSSPEGSCREVPQAASKTHGLLQAVRTQAQDKRPAVTSQPCPSAATHSLGLGSNLSFGSGAKRPAQAPIQACLNFPKKPRLGPFQIPESTIQGGELGAPENLQPPPAATELGPSRSPQMGRRTPAQVPSVERQPPHRRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :* . :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* :: .*. :..* .. *: . * * .. * : .*.* : * *: * *.** : . * :: * *..* :.: : .:.::: : *: . **. .. *. ..:*** : :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.::* * *..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 133, "similar_positions": 144, "identity": "28.66%" }, { "cls_id": "homologset.agr.HGNC:3227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52799-1", "uniprot_id": "EFNB2_HUMAN", "id": "P52799-1", "name": "Ephrin-B2", "aln": "---MA-VRRDSVWKYCWGVLMVLCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPTRRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNILGSEVALFAGIASGCIIFIVIIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRSG---NNNGSEPSDIIIPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52800-1", "uniprot_id": "EFNB2_MOUSE", "id": "P52800-1", "name": "Ephrin-B2", "aln": "-MAMARSRRDSVWKYCWGLLMVLCRTAISRSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCARPDQDVKFTIKFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSARNHGPTRRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNLLGSEVALFAGIASGCIIFIVIIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRGG---NNNGSEPSDVIIPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O73874-1", "uniprot_id": "EFNB2_DANRE", "id": "O73874-1", "name": "Ephrin-B2a", "aln": "MG-------DSLWRYYFGVLVIACKVNLSRALILDSIYWNTTNTKFVPGQGLVLYPQIGDKMDIVCPRVEGGSMEGVEYYKLYMVPLEQLKSCQVTKADTPLLNCVKPDQDVKFTLKFQEFSPNLWGLEFFRGKDYYIISTSNGTMEGLDNQEGGVCKTKSMKIIMKVGQNPSDPISPKDY-PTSYPPKHPDLGGKDSKSNEVLKPDASPHGEDKGDGNKSSSVIGSEVALFACIASASVIVIIIIIMLVFLLLKYRRRHRKHSPQHATTLSLSTLATPKRGGSGGNNNGSEPSDIIIPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*:* :*:*:: *:. :*::::*:.****::*:**:**************:**:**:*:. :: ****:*** :* . * :.* :******.:****:***:************** :.***********::***********:*::***:*****:.*.. *.:: ** * ... .*:.*.:. .:**:... :.:. *:....::******** ***..:*.*:*** **.****************:*************.* *********:********************************************", "identical_positions": 214, "similar_positions": 86, "identity": "62.94%" }, { "cls_id": "homologset.agr.HGNC:32270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKGLQKLS--------QAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MWA6-1", "uniprot_id": "F90AM_HUMAN", "id": "A8MWA6-1", "name": "Protein FAM90A22", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRARVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRAEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKTSLSSSSSLGPKERQTGAAADMPQPAVRHQGPEPLLEVKPTHSRPEGGCQEVPQAASKTHGLLQASRPQAQDKRPAVTPQPCPPAATHSLGLGSNLSFGPGAKKPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHSAAGHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: * ** .*****:**::****** **. ***:* : **. .** *: *** .* :*:. : . : * * :: **** :: * *.* * :*: .. . :* : . ..* :: .*.. :..* .. *: ..: : ** :. :...:.:*..*::* : :. : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :: :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 127, "similar_positions": 158, "identity": "27.37%" }, { "cls_id": "homologset.agr.HGNC:32271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKGLQKLS--------QAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MXZ1-1", "uniprot_id": "F90AN_HUMAN", "id": "A8MXZ1-1", "name": "Protein FAM90A23", "aln": "MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRSPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRAEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTPQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :*:. : . : * * :: **** :: * *.* * :*: .. . :* : . ..* :: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 128, "similar_positions": 158, "identity": "27.59%" }, { "cls_id": "homologset.agr.HGNC:32272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCRPKG--------LQKLSQAARQRCDEQQRKAPFQKF---PTELQWRNQQGTLAQP-----QMSIIPGYRKMSEPPVEMALGKPTGPEKPALQSLDGPFILHSRQ----------KEGHNMTVPGVAKPVFRQDGRK-TVSENLLDQKVQDISHQHPVAVPKRKSITELFHKESKTQGPSKKMQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIES---------GQALRMIFTKHSHNFWSSRFLTVPAPLPIEK-QTPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSSEDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7X0-1", "uniprot_id": "F90AO_HUMAN", "id": "P0C7X0-1", "name": "Protein FAM90A24", "aln": "MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQASRPQAQDKRPAVTPQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHSAAGHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: . * * *:: *. ** .*****:**::****** **. ***:* : **. .** *: *** .* :*:* :* .: * * :: **** :: * *.* * :*: .. . :* : . ..* :: .*.. :..* .. *: ..: : ** :. :...:.:*..*::**: : : ..: :. .:: * *..* :.: : : ::: : *: . **. .. *. ..:*** . :. :*.* *. * ** *:.. : **.: :. ::*. * *..* . : :*.:: ..****.*:* *.*..* :::.* * .*.**::* : .:. *** :*:.*: . ** : *** ..*:.**. :* *****************.: ", "identical_positions": 129, "similar_positions": 158, "identity": "27.8%" }, { "cls_id": "homologset.agr.HGNC:32275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9H2-1", "uniprot_id": "A0ABK0L9H2_RAT", "id": "A0ABK0L9H2-1", "name": "", "aln": "-----------MERGRPSSSPRSAEPAPPAAAAAAAARDSSPGQTGAGPTGPGGVAARSGSGRPAAANAARERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDTDAPGDPSLGALRGDGYLHPVKKWPMRSRLYIGATGQFLK-HSVPGEKGSHNDAPAASPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "V9GWT9-1", "uniprot_id": "V9GWT9_MOUSE", "id": "V9GWT9-1", "name": "", "aln": "-----------MERGRPASSPRSAESAAPP----AAARDWSPGPTGTGPTGLSGVAARSGGGRPAAANAARERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDTDAPGDPGLGALRGDGYLHPVKKWPMRSRLYIGATGQFLK-HSVSGEKASHSNTSTASQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU0-1", "uniprot_id": "TCF24_HUMAN", "id": "Q7RTU0-1", "name": "Transcription factor 24", "aln": "-----------MDRGRPAGSPLSASAEPAP--LAAAIRDSRPGRTGPGPAGPGG-GSRSGSGRPAAANAARERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAGLGALRGDGYLHPVKKWPMRSRLYIGATGQFLK-HSVSGEKTNHDNTPTDSQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PV37-1", "uniprot_id": "A0A8M1PV37_DANRE", "id": "A0A8M1PV37-1", "name": "", "aln": "MAERALDEDMAWQRGEDGGKSLRTQTWNQTCVKLATQREAKKWVK-SGPT----ASSRACKSQTSPENAARERSRVRNLRQAFHSLQAALPSVPPDTKLSKLDVLVLATNYIAHLTETL-DQGGMLGDQ--SVLQRVEYLHPVKKWPMRSLLYCGNIGERLTGAQVSQETASKAESRLTN--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**. .... :.. . *: *: . .**: .:*: .:.:. *********:.**:** .** :****************:***.******.:* *: .* ..*: ************ ** * *: *. .*. *. .: :: . ", "identical_positions": 70, "similar_positions": 47, "identity": "38.46%" }, { "cls_id": "homologset.agr.HGNC:3228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15768-1", "uniprot_id": "EFNB3_HUMAN", "id": "Q15768-1", "name": "Ephrin-B3", "aln": "MGPPHSG-------PGGVRVGALLLLGVLG--LVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGG-AQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP--GSFG--RGGSLGLGGGGGMGPRE-AEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V7D4-1", "uniprot_id": "G3V7D4_RAT", "id": "G3V7D4-1", "name": "Ephrin-B3", "aln": "MGGPHFG-------PGGVQVGALLLLGFAG--LVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPSYEFYKLYLVGG-AQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSQEPGKDSIPGDPNSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP--GSFG--RGGSLGLGGGGGMGPRE-AEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35393-1", "uniprot_id": "EFNB3_MOUSE", "id": "O35393-1", "name": "Ephrin-B3", "aln": "MGAPHFG-------PGGVQVGALLLLGFAG--LVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPSYEFYKLYLVEG-AQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSAEPGRDTIPGDPSSNATSRGAEGPLPPPSMPAVAGAAGGMALLLLGVAGAGGAMCWRRRRAKPSESRHPGP--GSFG--RGGSLGLGGGGGMGPRE-AEPGELGIALRGGGTADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8RI02-1", "uniprot_id": "A0A2R8RI02_DANRE", "id": "A0A2R8RI02-1", "name": "Ephrin-B3", "aln": "MGIQTRGAWVAMAFSDWVSALGFLLIFLMESLAVDATNMEPVYWNTLNRRFGDERGYILYPQIGDRLDLVCPATSPAGPNSPPEYEFYKLYLVSTREQADRCEVMGAPNLLLTCDKPNSDMRFTIKFQEYSPNLWGHEFKNLRDYYIIATSDGTKEGIDSMRGGVCVTRGMKLVLKVGQTAYG--LPPKPK------PDPGRPNSKIPDTE-----SGSKGGETSESGAVSASNIALISGGAGGAFILLIAIVIA--VVCYRRRKAKHSETHHPALTLSSLTPKRGSSGGTATGSSGGNNNGSEPSDIIIPLR---TSDSAYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * .. * . .:**: . *.. .:******: *:** * **:***********:** : *.**:*.*.********* *. ***. *********:*: *:******************:. :***********:**::*::****:*****::*:***:. * :* ** * * .:* *. : . *:. . . .*.:....:. ::*.*** :**:.:. * .:*:***:** **::**. .*: **.* * . *.. * .: :**.:: *.** ::*..:*******************: *****.******", "identical_positions": 176, "similar_positions": 93, "identity": "49.58%" }, { "cls_id": "homologset.agr.HGNC:3229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07522-1", "uniprot_id": "EGF_RAT", "id": "P07522-1", "name": "Pro-epidermal growth factor", "aln": "-------MLFSLTFLSVFLKITVLSVTAQQTRNCQSGPLERSGTTTYAAAGPPRFLIFLQGNSIFRINTDGTNHQQLVVDAGVSVVMDFHYKEERLYWVDLERQLLQRVFFNGSGQETVCKVDKNVSGLAINWIDGEILRTDRWKGVITVTDMNGNNSRVLLSSLKRPANILVDPTERLIFWSSV-VTGNLHRADLGGMDVKTLLEAPERISVLILDILDKRLFWAQDGREGSHGYIHSCDYNGGSIHHIRHQARHDLLTMAIFGDKILYSALKEKAIWIADKHTGKNVVRVNLDPASVPPRELRVVHLHAQPGTENRAQASDSERCKQRRGQCLYSLSERDPNSDSSACAEGYTLSRDRKYCEDVNECALQNHGCTLGCENIPGSYYCTCPTGFVLLPDGKRCHELVACPGNRSECSHDCILTSDGPLCICPAGSVLGKDGKTCTGCSFSDNGGCSQICLPLSLASWECDCFPGYDLQLDRKSCAASMGPQPFLLFANSQDIRHMHFDGTDYKTLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANLDGSQRERRITEGVDTPEGLAVDWIGRRIYWTDSGKSVIEGSDLSGKHHQIIIKESISRPRGIAVHPKARRLFWTDTGMSPRIESSSLQGSDRTLIASSNLLEPSGIAIDYLTDTLYWCDTKLSVIEMADLDGSKRRRLTQNDVGHPFSLAVFEDHVWFSDWAIPSVIRVNKRTGQNRVRLRGSMLKPSSLVVVHPLAKPGADPCLHRNGGCEHICQESLGTAQCLCREGFVKAPDGKMCLTRKDDQILAGDNADLSKEVASLDNSPKAYVPDDDRTESS-TLVAEIMVSGLNYEDDCGPGGCGSHAHCISEGEAAVCQCLKGFAGDGNLCSDIDECELGSSDCPPTSSRCINTEGGYVCQCSEGYEGDGIYCLDVDECQQGSHGCSENATCTNTEGGYNCTCAGCPSAPGLPCPDSTSPSLLG-------KDGCHW-VRNSNTGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLRWWKLRHADYGQRHDITVVSVCVVALALLLLLGMWGTYYYRTRKQLSESSKKPSEESSSNVSSNGPDSS-GAGVSSGPQPWFVVLEEHQQPKNGRLPAAGTNGAVVEAGLSSSL--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01132-1", "uniprot_id": "EGF_MOUSE", "id": "P01132-1", "name": "Pro-epidermal growth factor", "aln": "MPWGRRPTWLLLAFLLVFLKISILSVTAWQTGNCQPGPLERS-ERSGTCAGPAPFLVFSQGKSISRIDPDGTNHQQLVVDAGISADMDIHYKKERLYWVDVERQVLLRVFLNGTGLEKVCNVERKVSGLAIDWIDDEVLWVDQQNGVITVTDMTGKNSRVLLSSLKHPSNIAVDPIERLMFWSSE-VTGSLHRAHLKGVDVKTLLETGG-ISVLTLDVLDKRLFWVQDSGEGSHAYIHSCDYEGGSVRLIRHQARHSLSSMAFFGDRIFYSVLKSKAIWIANKHTGKDTVRINLHPSFVTPGKLMVVHPRAQPRTEDAAKDPDPELLKQRGRPCRFGLCERDPKSHSSACAEGYTLSRDRKYCEDVNECATQNHGCTLGCENTPGSYHCTCPTGFVLLPDGKQCHELVSCPGNVSKCSHGCVLTSDGPRCICPAGSVLGRDGKTCTGCSSPDNGGCSQICLPLRPGSWECDCFPGYDLQSDRKSCAAS-GPQPLLLFANSQDIRHMHFDGTDYKVLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANMDGSQRERLITEGVDTLEGLALDWIGRRIYWTDSGKSVVGGSDLSGKHHRIIIQERISRPRGIAVHPRARRLFWTDVGMSPRIESASLQGSDRVLIASSNLLEPSGITIDYLTDTLYWCDTKRSVIEMANLDGSKRRRLIQNDVGHPFSLAVFEDHLWVSDWAIPSVIRVNKRTGQNRVRLQGSMLKPSSLVVVHPLAKPGADPCLYRNGGCEHICQESLGTARCLCREGFVKAWDGKMCLP-QDYPILSGENADLSKEVTSLSNSTQAEVPDDDGTESS-TLVAEIMVSGMNYEDDCGPGGCGSHARCVSDGETAECQCLKGFARDGNLCSDIDECVLARSDCPSTSSRCINTEGGYVCRCSEGYEGDGISCFDIDECQRGAHNCGENAACTNTEGGYNCTCAGRPSSPGLSCPDSTAPSLLG-------EDGHHL-DRNSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELRHAGYGQKHDIMVVAVCMVALVLLLVLGMWGTYYYRTRKQLSNPPKNPCDEPSGSVSSSGPNSSSGAAVASCPQPWFVVLEKHQDPKNGSLPADGTNGAVVDAGLSPSLQLGSVHLTSWRQKPHIDGMGTGQSCWIPPSSDRG--PQEIEGNSHLPSY----RPVGPEKLHSLQSANGSCHERAPDLPRQTEPVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01133-1", "uniprot_id": "EGF_HUMAN", "id": "P01133-1", "name": "Pro-epidermal growth factor", "aln": "------MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGN--GNSTCVGPAPFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSE-VAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAAS-GPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVS---DQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLR-------EDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADT-EDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTS---------WRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPHQMELTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B8-1", "uniprot_id": "A0AB13A7B8_DANRE", "id": "A0AB13A7B8-1", "name": "Pro-epidermal growth factor", "aln": "--MCWRTIALTFGLWSWMVSMDPLRASGPAEEALCWGGRAWA-AGNFNCVEPEPYLIVGLGNSIQRMNLDGGDRRRIVSRAGRSILLDFHLSEWTMFWADTQTGQIRRAGLDGTRRQKLLSSVKGITGLVVDWIENSVLWSNADEGTIQRMDTDGRNDRVVLRNLSQPRGVVVDPNERYIFWLSDGATSSIQRSDMTGKMMSTVLKVADRLKVLAVDHRDRRLFWVQQGQRG-HTAMGSCNYDGNIINVFNQQFRPQSLRMTIFLDYVYLSDSKSKTITRLNKYTGGRQENVSSQRMPHSPADVKVVHPINQPVVETPFTPG----CSRHTGECVK-VCSSHTDTGLCGCKDGFTLSKHGNICEDVNECSLWNHGCSLGCENVPGSYFCTCPEGYLLLPDLKTCQENKPCVGKAVDCDHACVHTAQGDMCVCPEGSLLNPDGQSCTGCFSADRGGCSQMCVTLYPGRWVCECHPGYQIQPDGKHCAAT-GPPADLLFANIVDLRKINTDGKLSIKLLEKPGGNITAVDYDPVTNKVYFADKGLKHIERASLDEGFRELLVSTGLNSPEALAVDWIQRKLYWTDSGLSSISRSSLNGLDREIFINENIQKPRGIALHPQAQKIYWTDMGDRPAVERSGLDKDLREAVVSTGLVSPSGLAVDHGSQRLYWCDMSTSVIESANLDGSHRRVISQNQVDRPFDIAVFENVLWVSDLENHLIFRLDMRSGQNPERLLVDSIQPAALVVVHPLAKPGADVCLDGNGGCAQVCVSRLGLPHCSCHTNHVLSADGKGCRM---------INASFSESSEGGSNDGLRNKTLNDESTPLAMLYTEKMVS---DQDDCFSLSCVVNAQCFLQEGRAVCQCVRGFTGDGELCVDVDECKAGLADCSVSEAECVNTAGGYFCQCKNGFSGDGHHCVDIDECRLDLHDCDVNAECLNAVGEYQCRCRSGFTGTGFSCQAEFNGTSLWPSTASPPDVTSTLQHKNGVQSCPSTHDSYCLYDGVCFYFPDMESYACNCVLGYMGERCQFSDLEWWELQQAEEGKRR-NMVIAVCIVLLITILSIAACITFCYRPKRHFGGCS---LQDSVGEMSASEDSFT---ETTTATPEVYVVLDTSTCTADKVLHVQSTTSTICSSCPTQTG---------DRFSSEEAGKLQRDGCSLAVA----------------------ICSVSCDIPKILLTEKTTDNLISLEDAQSPTSSQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .: : :. * . .. * :*:. *:** *:: :* : .::* ** * :*:* .: ::*.* : : *. ::*: : : . : ::*:.::**: .:: : :* * * *.*.:::* *. * .: *** ** :** * .:..: *:.: * :.::*:. :..: :* *:**** * . .* : : **:*:*. :. .: : . *::* * : * * *:* :*:** .:. . . .: *** ** .* . : * :. . .: . * :*::**:. : *******: ****:***:* ****.**** *::**** * *:: .* : .*.* *: *::* *.** **:* **::*:** .*.*****:*:.* * *:*.***::* * * ***: ** . ***** *:*::: **. **.: * : *:*:*** .*:***...** ****.:* . ** : *:: *.**:*** *::**** * * : *.*.* .*: :* *.:*****:** *::::*** * * :* :.*: * :.*:.*: ***:::*. :: ***** . **** *:****:** : **:*.:** :****: :*.** ::*:: *:*:: ** . ::*::************* ** **** ::* . ** . * *: ..: : *** * :..:.:. . . :: : . * :* *** :*** . .* *:*. : * ***::**: **:** *:*** . . *. :.:.*:** ***.*:*.:*:.*** *.*:***: . *.*. ** * *: * * * * . : .*: * . . * . :*. ** ::*.*** .***::. :: *.****:** *:*** **.**:*::* *::: *::**:* * :* :. :. **.:: :. . ::. .: : : :: . :**:. : . . . .. : ", "identical_positions": 370, "similar_positions": 345, "identity": "29.91%" }, { "cls_id": "homologset.agr.HGNC:32291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M3C0-1", "uniprot_id": "A0ABK0M3C0_RAT", "id": "A0ABK0M3C0-1", "name": "", "aln": "-MQARRLAKRPSLGSRRGGAAPAPAPEAAALGLPPPGPSPAAAPGSWRPPLPPPRGTGPPRAAAASSPVLLLLGEEDEDEEGAGRRRRTRGRVAEKPRGGAEEEEDDEEEDEEVVVEVVDGDEDDEDSEERFVPLGPGRALPKGPARGAVKVGSFKREMTFTY---QSEDFRRDSSKKLSH-----HLFPLAMEEDVRTADTKKASRILDQ--DKE-TRSVCLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLT-SLSTSPLVRSPPVRPNEGLSGSWKEG--APSSSSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSP---VPLDDGIDEAEASNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLNTAAGIQKHIRAVHLGRVGESDCSD--GEEDFYYTEIKLNTDAVAEGLNSVAPVSPSQSLASPP----------------------------------------------------------------------------------TFPIPDSSRAETPCAKTDTKLVTPLSRSAPTTLYLVHTDHAYQATPPVTIP--GSAKFTPNGSSFSISWQSP----------------------------------------------------PVTFTGVPKAQRRRQKVPQGLRD------------------------GKQGHVVHRLPLEEGLPAVHRLSRGAGSPQPFLPLPLKGATQGPGKALLEFQEYNSLVELKQKLSTALL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERQ3-1", "uniprot_id": "ZN704_MOUSE", "id": "Q9ERQ3-1", "name": "Zinc finger protein 704", "aln": "-MQARRLAKRPSLGSRRGGAAPAPAPEAAALGLPPPGPSPAAAPGSWRPPLPPPRGTGPSRAAAASSPVLLLLGEEDEDEEGAGRRRRTRGRVTEKPRGVAEEEDDDEEEDEEVVVEVVDGDEDDEDAEERFVPLGPGRALPKGPARGAVKVGSFKREMTFTF---QSEDFRRDSSKKPSH-----HLFPLAMEEDVRTADTKKTSRVLDQ--EKE-TRSVCLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLT-SLSTSPLVRSPPVRPNEGLSGSWKEG--APSSSSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSP---APPDDGIDEADASNLLFDEPIPRKRKNSMKVMFKCLWKSCGKVLNTAAGIQKHIRAVHLGRVGESDCSD--GEEDFYYTEIKLNTDATAEGLNTVAPVSPSQSLASAP----------------------------------------------------------------------------------AFPIPDSSRTETPCAKTDTKLVTPLSRSAPTTLYLVHTDHAYQATPPVTIP--GSAKFTPNGSSFSISWQSP----------------------------------------------------PVTFTGVPVSPPHHPTAGSGEQ-------------------------RQHAHTALSSPPRG--TVTLRKPRGEG----------KKCRKVYG---MENRDMWCTACRWKKACQRFID-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNC4-1", "uniprot_id": "ZN704_HUMAN", "id": "Q6ZNC4-1", "name": "Zinc finger protein 704", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MTFTF---QSEDLKRDCGKKMSHQ----HVFSLAMEEDVKTADTKKASRILDH--EKENTRSICLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLT-SLSTSPLVRSPPVRPNESLSGSWKEGGCVPSSTSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSP---AQPDDGIDEAEASNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGDSDYSD--GEEDFYYTEIKLNTDSVADGLSSLAPVSPSQSLASPP----------------------------------------------------------------------------------TFPIPDSSRTETPCAKTETKLMTPLSRSAPTTLYLVHTDHAYQATPPVTIP--GSAKFTPNGSSFSISWQSP----------------------------------------------------PVTFTGIPVSPTHHP-VGTGEQ-------------------------RQHAHTVLSSPPRG--TVSLRKPRGEG----------KKCRKVYG---MENRDMWCTACRWKKACQRFLD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY51-1", "uniprot_id": "ZN704_DANRE", "id": "Q1LY51-1", "name": "Zinc finger protein 704", "aln": "-MHTRRLVKRSVIGSR----------------VYAPGLTGDAAP-----------LTGVIQAVKQ-----------DNRDASTGHRRN--------------------------VYTVLMQDGSVKEYSEEEIAQMTAKAPLKSSLKSTCNGG--QRDGLTQG---QNGGVQRGEALSLSP----------ESTEEPRVLEHKRTGRALET--EKDHTRSVSLLEQKRKVVSSSIDVPQARKSEEEVDMDKVTAAMVLT-SLSTSPLVRSPPVKVSEGLNGSWKDGGFTPSSYSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRMPSLSGPPDDNIDEHDGNSLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQRHIRTVHLGRNCDSECSD--GEEDFYYTEIKLNTDSVADGLSSLSPVSPS-VLSPPP----------------------------------------------------------------------------------ALDQRQPDGTNG--TKSESSSSTPLSRSAPSALYLVHTDHAYQATTPVTIPSTSSTGFTPSSSSFSISWQSP----------------------------------------------------PVTFTGTSASPTHSRTQGFGEQ-------------------------HSQTIAVLSSPPRAA-GSLSRKSRGEG----------KKCRKVYG---MENRDMWCTACRWKKACQRFVD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFN3-1", "uniprot_id": "A0A0B4KFN3_DROME", "id": "A0A0B4KFN3-1", "name": "", "aln": "MSTGRRLAKRSIIGTKVCAKGPDGLWYSGTISDVKTPPSYSGPLSPPPPPTFVVPGEAPINADTRYLVRFDFKTAVESPTATTSSAASTSSTSSTDPSVIVETRRAAN--VHISPAQALRRSAMIKEFRESDLIGPGFRSIMDTELQPGQRVYFTYNGREQSGDVVKHDATKDEVIVKITTVGNEEPIELKKRLEEVRLLESRRSARLADQDRDTDFARLADMSGERRRTTTHSIEVPSQLTAQHNSRKRPPSDHQDYGNYLETCRAAEILSSMKLQSPHGSMADKCSSPGS-SSSASWSSGSPSPPLSDDGHAHHSPHNIMSPHDADN--ARTRTASVSTSDEGIVIDYKEERKKKS---KKFRCVYRGCVGVVDDLNGVVRHIRKTHLGKDSHRSADDDGNEEDFYLEDADDDVEQVKPTLASEPTLSHRDMARPPHEDPEYQKQIVGNFKQGRGGSHYNHLAQSHGRTISGSNIPSTHQQQLQNNNTSCIPTSHLAHHNYTCPAATATVGSYSSTGTGSVAASSSASPIGKHARSSSSRPTHSVAPYPSPTYVQQQQHHQHTHHHNYAGSSGSSNSSSSSSPVIHSNSSANNMLQQLSQQNVTVTAHHSQQQQQLQQQQHHQQQQQHSHQQQQQHLLSSVTITPNFHPAQQQHHHQPMRGHQQQHPQTTAGNMVAQNNSNNHSNGSNPLQQQQHMAQQVAVKHTPHSPGKRTRGEN----------KKCRKVYG---MEKRDQWCTQCRWKKACSRFGDXKRQKSSTEAANQASAHQSKAATAASSAALSSSASATATPNPEAISATPSPAATSSTSSKMTTTVVRLAAEVAAGKQLPSSLTIKTNKRYGGPVQQQQQQPHPYAVTANSNTISNRPVRIRSVATSVIVAPIACAATTTNTTPSHMEDTDADEDADEELEEMEQEDQEQVDPEALEDQEEAQVAAANGLLAWSRAAANQQQAQAVLMQG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : *: : : :::.* : :.: :* : ::*:..: .*:** .:..: : *.*. .. . :. ** : *.* ***. ** .:** . . : . : :.*. . . ..:::* **:*. *:*:::.* *:. *: :*** ***: . . .* .***** : . :.: . * : ..:* .. :. .. . :::.:. * . *:. *: : :* :: .*: :...*.. * .*. . .* : : .: . . . : .** . * . : * :* :: . :* . : ", "identical_positions": 59, "similar_positions": 136, "identity": "6.08%" }, { "cls_id": "homologset.agr.HGNC:32296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT70-1", "uniprot_id": "D3ZT70_RAT", "id": "D3ZT70-1", "name": "", "aln": "MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARRSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLRETKGCSITEAVTILGKKLQDYQKQFNVTHLLALCDYFHNTFIRHYRLYQYVLSQDQEVNLTVAHVQMCTPPQPLPLTDGKDRDVWKHEQQVAELSAAEAEKRSDVLVLKETLRMEQAQMLQKAFGVEEAPTQLQPRPTLRREALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITAGPAALEDSPKASKANKGKKAKAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZQ3-1", "uniprot_id": "CH074_MOUSE", "id": "Q80ZQ3-1", "name": "Uncharacterized protein C8orf74 homolog", "aln": "MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARQSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLKETKGCSITEAVTILGKKLRDYQKQFNVTHLLALCDYSHNTFIRHYRLYQYVLSQDQEVNLTVAHEQICAPPQPLPLTDGTDRDVWRHEQQVAELSTAEVEKRANVLMLKETLRMEQAQMLQKAFGVEEAPGQLQPHPTLRKEALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITTGPAALEDSPKASKANKGKKAKAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P047-1", "uniprot_id": "CH074_HUMAN", "id": "Q6P047-1", "name": "Uncharacterized protein C8orf74", "aln": "MALLTPQGVKEVFQLQRPQGRERLRRLLNWEEFDEQRDSRRSILLDTLYESIIFAVGKGFPWVEVAQVVKFTEELLRETKGCSITEAVTILGNKLRDYRGHFNTTHLLALCDYFHHTFIRHYKLYQYVLGQDQQVDLTVAHLEVCMPPHPLPLAEGMDRDLWIHEQQVATLTEAEAQKRADVLLLKEALRLERENSLQKAF---AAAAPAQPGQVLERQELESLICQAVHTQMELLQELLQRQIQNTFAILDLKLQKKTLNLNAPTPIPPPITS-HAGQEEALKPQRASKGKKAKARK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RRK3-1", "uniprot_id": "A0A8M1RRK3_DANRE", "id": "A0A8M1RRK3-1", "name": "", "aln": "-MMASIHTLQEISRMKRDEGIDRLSRCFEWMGFDG-DDKRQFLHQEFVYENVMFAVTRGLPWSTVGQVAIISKDLLPKINGLKSSEVISLVKAGLSQINPRLSATHHAVLLDFIVQTYVPHQRLYQAAFSGETSLKRISQDLQIETPPQPRPLSEGTDTERWKQQQILQELRLAQSRTQAEIQELRETSRTQIMSTLQDKL------HSLPDEGQISRQEVEELLHSFLRSQGEIMMESLTKETRLTENLLQVKLRQSEVQRQLAN------TPVFPEKQTSITPTRSKKKGN-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::*: :::: :* ::* * ::* ** * *: : : :*:.::*** :*:** * **. ::::** : :* . :*.:::: * : . ::..** .* *: :*:: * :*** .:. : .:. . :: **:* **::* * : * ::* : * *: ..:::: *:*: * : . **. : : :: :* *: . :: * : * * : : : :*:::*::. :. . . *. . : : .. ::.* : ", "identical_positions": 58, "similar_positions": 114, "identity": "19.46%" }, { "cls_id": "homologset.agr.HGNC:3230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88278-1", "uniprot_id": "CELR3_RAT", "id": "O88278-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "-----MARRPLWWGLPGPSTPLLLLLLFSLFPSSREE----------------------------MGGGGDQGWDPGVATATGPR---------AQIGSGAVALCPESPG-------------------VWEDGDPGLG------VREPVFMKLRVGRQNARNGRG----------------------------------------------APEQPNREP----VVQALG---------------------SREQEAGQGSGYLLCWHP------------EISSCGR---------------------------------------------------------------TGHLRRGSLP-----------------------LDALSPGDSDLRNSSPHPS-----------ELLAQPDSPR---------------------------PVAFQRNGRRS-----------------------------------------------------IRKRVETFRCCGKLWEPG-HKGQGERSATSTVDRGPLR--RDCLPGSLGSGLGEDSAPRAVRTAPAPG--------------------------------SAPHESRTAPE----RMRSRG-------------LFRRGFLFERPGPRPPGFPTG---AEAKRILSTN-------------------QARSRRAANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDPGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHAPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRY----RFVGSPAARTAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR-SATVRVHITVLDENDNAPQFSEKRYVAQVREDVR---PHTVVLRVTATDKDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVMAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHSPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENSRLEYSLTGVASDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGMGLVTLALPLDYKQERYFKLVLTASDR-ALHDHCYVHINITDANTHRPVFQSAHYSVSMNEDRPVGSTVVVISASDDDVGENARITYLLEDN-------LPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVPVYELTAYAVDRGVPPLRTPVSIQVTVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDDGPNAHIMYQIVEGNIPELFQMDIFSG----ELTALIDLDYEAR-QEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGHFLEGVAAVLATPTEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTG----DFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTNAPNGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQPSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESSTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCNVAVALRFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSRKDFIGCMRDLHIDGRRVDMAAFVANNGTTAGCQAKSHFCASGPCKNGGLCSERWGGFSCDCPVGFGGKDCRLTMAHPYHFQGNGTLSWDFGNDMPVSVPWYLGLSFRTRATKGVLMQVQLGPHSVLLCKLDQGLLSVTLSRASGHAVHLLLDQMTVSDGRWHDLRLELQEEPGGRRGHHIFMVSLDFTLFQDTMAMGSELEGLKVKHLHVGGPPPSSKEEGPQG-LVGCIQGVWTGFTPFGSSALPPPSHRINVEPGCTVTNPCASGPCPPHANCKDLWQTFSCTCWPGYYGPGCVDACLLNPCQNQGSCRHLQGGPHGYTCDCASG-YFGQHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTSGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALGLRGTGAAVRLCDEDHG-WLEPDFFNCTSPAFRELSLLLDGLELNKTALDTVEAKKLAQRLREVTGQT-----------------------------------------------------DHYFSQDVRVTARLLAYLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMDLTYLNPVGLVTPNIMLSIDRME-----------------------------------------QPSSSQGAHRYPRYHSNLFRGQDAWDPHTHVLLPSQSP--------------------------------------------------------------------------------QPSPSEVLPTSSN-------AENATASGVVSPPAP--LEPESEPGISIVILLVYRALGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFRGRNFLRG---------------------------------------------------------------ALVSPINLEFRLLQTAN----RSKAICVQWD-PPGPADQHGMWTAR-----DCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAASVTALVLTAAVLLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHR----THNQLLCTVVAILLHYFFLSTFAWLLVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISIHEPLIWSFAGPIVLVIVMNGIMFLLAARTSCSTGQREAKKTSVLRTLRSSFLLLLLVSASWLFGLLAVNHSVLAFHYLHAGLCGLQGLAVLLLFCVLNADARAAWTPACLGKKAAPEET-RPAPGPGSGAYNNTALFEESGLIRITLGASTVSSVSSARSGRAQDQDSQRGRSYLRDNVLVRHGSTAEHAEHSLQAHAGPTDLDVAMFHRDAG----------ADSDSDSDLSLEEERSLSIPSSESEDNGRTRGRFQRPLRRAAQSERLLAHP-----KDVDGNDLLSYWPALGECEAAPCALQAWGSERRLGLDSNKDAANNNQPELALTSGDETSLGRAQRQRKGILKNRLQYPLVPQ-----TRGTPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSRERLEEVPVPAPVLHPLSRPGSQERLDTAPARLEPRDRGSTLPRRQPPRDYPGTMAG-RFGSRDALDLGAPREWLSTLPPPRRNRD-------LDPQHPPLPLSPQRPLSR-DPLLPSRPLDSLSRISNSRERLDQVPSRHPSREALGPAPQLLRAREDPASGPSHGPSTEQLDILSSILASFNSSALSSVQSSSTPSGPHTTATPSATASALGPSTPRSATSHSISELSPDSEVPRSEGHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZI0-1", "uniprot_id": "CELR3_MOUSE", "id": "Q91ZI0-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "-----MARRPLWWGLPGPSTPVLLLLLLSLFPFSREE----------------------------LGGGGDQDWDPGVATTTGPR---------AQIGSGAVALCPESPG-------------------VWEDGDPGLG------VREPVFMRLRVGRQNARNGRG----------------------------------------------APEQPNAEV----VVQALG---------------------SREQEAGQGPGYLLCWHP------------EISSCGR---------------------------------------------------------------TGPLRRGSLP-----------------------LDALSPGDSDLRNSSPHPS-----------ELLAQPDGSR---------------------------PVAFQRNARRS-----------------------------------------------------IRKRVETSRCCGKLWEPG-HKGQGERSATSTVDRGPFR--RDCLPGSLGSGLGEDSAPRAVRTAPTPG--------------------------------SAPRESRTAPG----RMRSRG-------------LFRRRFLFERPGPRPPGFPTG---PEAKQILSTN-------------------QARPRRAANRHPQFPQYNYQTLVPENEAAGTSVLRVVAQDPDPGEAGRLIYSLAALMNSRSLELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHAPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRY----RFVGSPAVRTAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR-SATVRVHITVLDENDNAPQFSEKRYVAQVREDVR---PHTVVLRVTATDKDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVMAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHAPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENSRLEYSLTGVASDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDR-ALHDHCYVHINITDANTHRPVFQSAHYSVSMNEDRPVGSTVVVISASDDDVGENARITYLLEDN-------LPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVPVYELTAYAVDRGVPPLRTPVSIQVTVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDDGPNAHIMYQIVEGNIPELFQMDIFSG----ELTALIDLDYEAR-QEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNRTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGHFLEGVAAVLATPTEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASTSTLFRPIQPIAGLRCRCPPGFTG----DFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFT--DCELDTEAGRCVPGVCRNGGTCTNAPNGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQPSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCNVAVALQFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFIGCMRDLHIDGRRMDMAAFVANNGTMAGCQAKSHFCASGPCKNNGFCSERWGGFSCDCPVGFGGKDCRLTMAHPYHFQGNGTLSWDFGNDMAVSVPWYLGLSFRTRATKGILMQVQLGPHSVLLCKLDRGLLSVTLNRASGHTVHLLLDQMTVSDGRWHDLRLELQEEPGGRRGHHIFMVSLDFTLFQDTMAMGGELQGLKVKQLHVGGLPPSSKEEGHQG-LVGCIQGVWIGFTPFGSSALLPPSHRVNVEPGCTVTNPCASGPCPPHADCKDLWQTFSCTCRPGYYGPGCVDACLLNPCQNQGSCRHLQGAPHGYTCDCVSG-YFGQHCEHRVDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALG-----AAVRLCDEDQG-WLEPDLFNCTSPAFRELSLLLDGLELNKTALDTVEAKKLAQRLREVTGQT-----------------------------------------------------DHYFSQDVRVTARLLAYLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGHLWAALGQRAPGGSPGSAGLVQHLEEYAATLARNMELTYLNPVGLVTPNIMLSIDRME-----------------------------------------HPSSTQGARRYPRYHSNLFRGQDAWDPHTHVLLPSQAS--------------------------------------------------------------------------------QPSPSEVLPTSSN-------AENATASSVVSPPAP--LEPESEPGISIVILLVYRALGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRG---------------------------------------------------------------VLVSPINLEFRLLQTAN----RSKAICVQWD-PPGPTDQHGMWTAR-----DCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVTALVLTAAVLLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHR----THNQLLCTAVAILLHYFFLSTFAWLLVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISIHEPLIWSFAGPIVLVIVMNGTMFLLAARTSCSTGQREAKKTSVL-TLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQGLAVLLLFCVLNADARAAWTPACLGKKAAPEET-RPAPGPGSGAYNNTALFEESGLIRITLGASTVSSVSSARSGRAQDQDSQRGRSYLRDNVLVRHGSTAEHTERSLQAHAGPTDLDVAMFHRDAG----------ADSDSDSDLSLEEERSLSIPSSESEDNGRTRGRFQRPLRRAAQSERLLAHP-----KDVDGNDLLSYWPALGECEAAPCALQAWGSERRLGLDSNKDAANNNQPELALTSGDETSLGRAQRQRKGILKNRLQYPLVPQ-----SRGTPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSKERLEEVPVPAPVLHPLSRPGSQERLDTAPARLEARDRGSTLPRRQPPRDYPGTMAG-RFGSRDALDLGAPREWLSTLPPPRRNRD-------LDPQHPPLPLSPQRQLSR-DPLLPSRPLDSLSRISNSREGLDQVPSRHPSREALGPAPQLLRAREDPASGPSHGPSTEQLDILSSILASFNSSALSSVQSSSTPSGPHTTAT----ASALGPSTPRSATSHSISELSPDSEVPRSEGHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYQ7-1", "uniprot_id": "CELR3_HUMAN", "id": "Q9NYQ7-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "----MMARRPPWRGLGGRSTPILLLLLLSLFPLSQEE----------------------------LGGGGHQGWDPGLAATTGPR---------AHIGGGALALCPESSG-------------------VREDGGPGLG------VREPIFVGLRGRRQSARNSRG----------------------------------------------PPEQPNEELGIEHGVQPLG---------------------SRERETGQGPGSVLYWRP------------EVSSCGR---------------------------------------------------------------TGPLQRGSLS-----------------------PGALSSGVPGSGNSSPLPS-----------DFLIRHHGPK---------------------------PVSSQRNAGTG-----------------------------------------------------SRKRVGTARCCGELWATG-SKGQGERATTSGAERTAPR--RNCLPGASGSGPELDSAPRTARTAPASG--------------------------------SAPRESRTAPEPAPKRMRSRG-------------LFRCRFLPQRPGPRPPGLPAR---PEARKVTSAN-------------------RARFRRAANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRY----RFVGPPAARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR-SATVRVHITVLDENDNAPQFSEKRYVAQVREDVR---PHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDR-ALHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDN-------LPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSG----ELTALIDLDYEAR-QEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGRFLEGVAAVLATPAEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTG----DFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQQSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGSFSCDCPVGFGGKDCQLTMAHPHHFRGNGTLSWNFGSDMAVSVPWYLGLAFRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTRGSGRASHLLLDQVTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQDTMAVGSELQGLKVKQLHVGGLPPGSAEEAPQG-LVGCIQGVWLGSTPSGSPALLPPSHRVNAEPGCVVTNACASGPCPPHADCRDLWQTFSCTCQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGG-YFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALG-----AAVRLCDEAQG-WLEPDLFNCTSPAFRELSLLLDGLELNKTALDTMEAKKLAQRLREVTGHT-----------------------------------------------------DHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYLNPMGLVTPNIMLSIDRME-----------------------------------------HPSSPRGARRYPRYHSNLFRGQDAWDPHTHVLLPSQSP--------------------------------------------------------------------------------RPSPSEVLPTSSS-------IENSTTSSVVPPPAP--PEP--EPGISIIILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRG---------------------------------------------------------------ILESPISLEFRLLQTAN----RSKAICVQWD-PPGLAEQHGVWTAR-----DCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHR----THNQLVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMNGTMFLLAARTSCSTGQREAKKTSAL-TLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQGLAVLLLFCVLNADARAAWMPACLGRKAAPEEA-RPAPGLGPGAYNNTALFEESGLIRITLGASTVSSVSSARSGRTQDQDSQRGRSYLRDNVLVRHGSAADHTDHSLQAHAGPTDLDVAMFHRDAG----------ADSDSDSDLSLEEERSLSIPSSESEDNGRTRGRFQRPLCRAAQSERLLTHP-----KDVDGNDLLSYWPALGECEAAPCALQTWGSERRLGLDTSKDAANNNQPDPALTSGDETSLGRAQRQRKGILKNRLQYPLVPQ-----TRGAPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSRERLEEA--PAPVLRPLSRPGSQECMDAAPGRLEPKDRGSTLPRRQPPRDYPGAMAG-RFGSRDALDLGAPREWLSTLPPPRRTRD-------LDPQPPPLPLSPQRQLSR-DPLLPSRPLDSLSRSSNSREQLDQVPSRHPSREALGPLPQLLRAREDSVSGPSHGPSTEQLDILSSILASFNSSALSSVQSSSTPLGPHTTATPSATASVLGPSTPRSATSHSISELSPDSEVPRSEGHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4X6-1", "uniprot_id": "A0A8M3B4X6_DANRE", "id": "A0A8M3B4X6-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "-------MAALLLDLGSLSPLLFLLLLSSLFTVIPGSGAGLCCRSRCTHPAPGDAQIASLPDGTITGALALGDWKIYPARTVGSRGRELQCSRSSAAGTPSVSLSPDYRNSSVWISEPAAHTGRCHRQPVWSDGGSGEKGVVSRVLASPVQYGKKRTVQRTRTRWRPKTRTVSFGTDSVFAHSVLDNCRTLDNKPRPNHCPYHPKREFAFAKTPTQPLLKAYSYSNVASDANKLHKATAHHPLSAPLNVIDLTREDWNGSSFGYVRGSSEPCARQLSPVLESETSSCLESYWITGCSERHPAWHSSYWHRFNISLMRYGVCVRQARENTNTTSSYNNSKAQFVHKKSHPNNPHGALRRDLISRVDCIRTDTRFDDRKANYNRSTGISAAPSYNGDVYNSDSSATGTPRGHNASQIYLLVELNFSKRFRDSYTHTRVIRSERAKDSAPGQWTAPFAVHEHAYSSDSTKSLFLMNWNTNNNNNCDKNHNNNNNNNNSSPGDQNANETQNVPDSNEREFIRGESARFPCSGARAERGDYKTDDSLNADGGATRPQLKSGKRVSLQAEGVSQQEEQLEAAAECGRREGQIEGGVKGEGRGEGDRQPVDGEWEESMEWVIAEDTKEERVLEGTNLQRKKEKGQGNDTSQSERESDDIKEGMWTEQNETKQSEVGVGNQYSEKQKYKDSDEVLREEGQEYSEEQTGIPSAGRSRRAANRQPQFPQYNYQVQVAENQPPGTSVIAMTAEDHDAGEAGRLSYSMAPLMNSRSMDYFQIDPITGLLTTTHILDREHMDLHYFRVTAADHGSPHLSGTTMVTITVADRNDHSPVFEQTEYRETIRENVEEGYPILQLRATDLDSTANANIRY----RFVGESAA--VARSAFEIDPRSGLITTRGIVDRETNERYTLLVEASDQGREPGPR-SATVSVHITVLDENDNVPQFSQKRYVVAVREDVR---PHSEILRISATDQDKDGNAAVHYNIISGNSRGQFAIDSVTGEIQVVAPLDFETEREYTLRLRAQDNGRPPLSNNTGIVSVQVTDVNDNPPIFVSTPFQATVLESAPIGHSILHIQAIDTDNGDNARLEYRLTGTGTDTPFVINAATGWVTVSSELDRESVEHYFFGVEARDYGSPPLSATASVTITVMDVNDNRPEFLQKEYYVRLNEDAAVGTSVVSVTAVDRDVNSAVTYQITGGNTRNRFAISTAGGAGLVSLALPLDYKQERRYVLTVTASDR-TLHDTCQVHINITDANTHRPVFQSAHYSVSVNEDRPPGSTVVVISATDDDVGENARITYYLEDN-------IPQFRIDPASGAITLQAELDYEDQMTYTLAITARDNGIPQKSDTTYVEVNVNDVNDNAPQFLSPRYQGGVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDRESVPFYELTAFAVDRGVPPQRTPVHIQVSVMDVNDNAPVFPADDFEVLVKENSAVGSVVAQITATDPDEGPNAQIMYQIVEGNIPEIFQMDIFSG----ELTSLIDLDYETR-NEYVIVVQATSAPLVSRATVRIRLVDQNDNGPQMQDFQIIFNNFVSNRSNTFPSGVIGRVPAHDPDVSDRLYYTIDRGNELHLLLLNHTSGEIRLSRKLDNNRPLVAPMLITVTDGIHSVSAQCVLRVLIITEEMLSSSITVRLQNMSQELFLSPLLTHFLDGVSAVLSVSPDDVFVFNVQPDADAG-KVLNVSFSAALP-------GGQFFPSEALEEQLYLNRPRLNALAHMEVLPFDDNVCLREPCQNYMKCISVLRFNSSAPFIASPSTLFRPIHPITGLRCRCPAGFTG----DYCEIEINLCYSNPCMNGGVCARREGGYTCICREDYTGERCEFDRRGGRCVAGVCRNGGTCRELSGGGFRCECPAG-GYEKPYCSVTTRSFPPKSFMMFRGLRQRFHLSISLSFATLESNGLLFYNGRFNEKHDFLALEILDGQMVLKYSTGESSTQVSPYLPGGVSDGNWHTVHIHYYNKPKRSVSGEVQGPSDEKVAVLSVDDCDTAVSLRFGAQLGNYSCAAQGRQTSSKKSLDLTGPLFLGGVPNLPENFPFSTREFIGCMKDLHIDNRPVDMAGFIANNGTLPGCSAKLPFCKSNPCQNGGTCRVSWETFSCDCPVGFGGKDCSLVMSHPHRFLGSSALWWDLKNEVTITTPWYMGLVFRTRSKEGVLLQAQAGQYTNLIFQVVGGQLVFSVARGSTRPVRLRLDQVQVCDGRWHDLQLELRDVRSGRETRYIATVRLDFGLYQGTVIVGNEINGVKVKHLHVGGVLGSG--EVQNG-IRGCIQGVRLGVRP-DSPALPRPSRTIKVETGCNVGNPCNSSPCPTHSQCTDEWDRHTCVCEPGFYGKSCMDACQLNPCENQAKCHRKPSSSHGYICDCEDS-HYGQYCQHRIEQQCPRGWWGSPTCGPCHCDASKGFDTDCNKTTGHCHCKEFHYRRRGSDICLPCDCYPVGSFSRSCDPESGQCQCRPGVIGRQCNMCDNPFAEVTQTGCEVIYDGCPKTITSAIWWPRTKFNLPAAVPCPKGSVG-----TAIRHCDGERG-WLDPDLYNCTSPPFVELNTALESLERNETELNTIIEKKLAHQLRDVTEAT-----------------------------------------------------SRLYGNDLQIAERLLSRLLTFESLQSGFGLTATQDAHFNENVLRGCSVLLGPASASLWRAQ----SSGQSGAAGLADLLEQYTRILAQNMKQTYLNPVALVAPNIVMTLDRVD-----------------------------------------NHTHVR--RRFPRYHSPLFRGQALWDAHTHVVLPPAAL--------------------------------------------------------------------------------VPQRNVFSAPSPAG------PVNLLANQTLEATAARRSLSLQEAPVSIVIILIYRSLGAALPPKYHTDRRGVRLPRHPVLNSPVVSISVYNNQTFVEG---------------------------------------------------------------FLESPVLLEFRLLETSN----RSKPLCVQWN-HSSIVSGGGCWTVR-----DCSVLYRNTSHVRCQCHRLGTFGVLMDSSQREQLEGDLETLAIVTYSSLSVSMAALLLTVLVLSCLRGLKSNTRSIHSNMAAATLLSHLTYLLGINQ----TEQQFLCTVVAILLHYFFMSAFAWLFVEALHIYRMQTEARNINYGAMRFYYAIGWGVPAIITGLAVGLDPEGYGNPDFCWISMYDKLMWSFAGPVSVVILMNGGMFLMVLRMTCNPTQKEIKKLPVISTIRSAFFLLLLSTCVWLFGLMAVNNSVLAFHYLFIILCCIQGLAVLLVFTVLNSEVQEAWKLACLGKKSPGEEPPRPPQITGQNPYNSASLLEQSGLHRITLGTSTISSVSSAR-----------------ENLLARQ------TLEHTLAHTGATDLDVAMFHRNGGTLTHNNLHACEDSDSDSDLSLEEERSLSIPSSESEDNVRLRGRIQRRFKRTGHGERLLTEATHNGGKDLDGNDLLSYWPALEGCEAH--SLQKWGSERRLGGDYNKDAANNNQPDAALTSGDEN--GLTHRHRKGILKNRLGCPPALQGLSAVGRAPSEMSWYRTSTLGHRGVPAASYGRMYSG--TGSLSQPASRYSSREHLDSLARRQRSRDNLDLLP-RRRELGAEHLGGSRERLGPVHSIHASREDLVGRGGLAGLMGAEGSLSGSRTQLNTLTRQQASREHLGGALMSSRSREQLESNGGAQPCREWLRTLPPRQLSHPDPHPPSSPPPPIT-----EEPHESLPSRRGRLDSAPPCRYPSSSAAAPGAPSSRPPSSEHLDILSSILASFSSSVLTPPPN---PAGPSP-----------SPPPPLSATSQSVSEVSPDSEVNRSDGQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V5N8-1", "uniprot_id": "STAN_DROME", "id": "Q9V5N8-1", "name": "Protocadherin-like wing polarity protein stan", "aln": "MQTREFPQRPLGLLLVLLVVLLQSSLIKSYLIIVHEDTPPG------------------------TVIFNASVYKLGSERHYKIN---------AHKSANFVHHLVSVN---------------------HKDGQIQLR---KALKCDGIYYPNLFTFYVDSTSNR----------------------------------------------LRSIDYYSLPVRIFVSGHS--------------------CNEDRRIEQELHHHHYEEE------------DNTGYSK-------------------------------------------------------------RRRRRSTQEMIQ-----------------------LNGNQLEEVFRQNSTEFRAG----------DLIFGDSFDN---------------------------EMRHRILSRKR---------------------------------------------------RAVGSPDPLHLQPALHRRISDAKQWISETYASYAIHTTDKWNQICLRRSQFINSLNAFLPRSVCQHCKVS------------------------------FLDVNDERFAIEHQSRDLVASRDVCIAES-------MWKVSITFNIRCDRRDIVDSDHRLKIVYHHQEFN--------------DTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDP---EDSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSN-TTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFR----DHFPSGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAFLSPLLNFFLDGLAAIIPCPKEHIFVFSIQDDTDVSSRILNVSFSARRP----DVSHEEFYTPQYLQERVYLNRAILARLATVEVLPFDDNLCVREPCLNFEECLTVLKFGNASEFIHSDTVLFRPIYPVNTFACSCPEGFTGSKEHYLCDTEVDLCYSDPCQNGGTCVRREGGYTCVCPSTHTGQNCETGVGHLRPCPSETCEGGLSCLSNYP------SSQPPPYTATCELRARAFGRNSFLTFESLKQRHRFNLKLRFATVQENGLLLYNGRYNELHDFIALEIHEGHVSFSFSLGDHSERISVIQEAKVSDGKWHQVEVVYLNRSVTLVLDNCDTAIALSGQLGDRWSCANRTTLKLDKRCS-------LLTETCHRFLDLTGPLQVGGLPRIPAHFPVTNRDFVGCISDLRIDDRFVDLNSYVADNGTLAGCPQKAPLCQSEPCFNGGTCREGWGTYSCECPEGYAGNSCQDNIPAPWRFSGDGSLSFNP-LLRPIQLPWTTSFSLRTRQKEAFLLQIQIGQNSSAAVCLRQGVLYYIFDGEP-----MYLAGAFLSDGEWHRVEIRWQQGSE-------IHFSVDYGQRSGSVPMSQKVQGLYVGKIVMGSPDGSIGAVPEASPFEGCIQDVRIGAGQ---SVLSRPTIRENVEDGCESRAQCP-DHCPNHSSCQSSWDLSTCECDSGYVGTDCAPICTVRPCAS-GVCRANTSLPRGYDCECNSSSRHGDYCEKELQQPCPGGWWGERVCGPCRCDLAQGYHPDCNKTTGQCYCKTNHYQPPNETACLSCDCYSIGSFSGACNPLTGQCECREGVIGRRCDSCSNPYAEVTLSGCEVVYDACPRSFAGGVWWPRTPLGGVAIEGCPPPARG-----KGQRSCDVQSGSWNTPDMYNCTSEPFVELRRQLSQLEKLELELNSFVAIKMAEQLRKACEAVDRRGASKDQKISGNGRPNRRYKMESSFLLSNGGNVWSHELEMDYLSDELKFTHDRLYGADLLVTEGLLQELINYELMQSGLNLSHSQDKYFIKNLVDAASVILDRKYEAEWRRATELIQRGP---DDLVDAFNKYLVVLARSQHDTYTSPFEIVQPNMALGLDIVTTESLFGYEPEQLSEYHRSKYLKPNAFTTESVVLPDTSGFLQHSARQRPVISFPKYNNYILD-RRKFDQHTKVLVPLEMLGITPPESDEISQSGRRGSSHDHRAIVAYAQYKDVGQLLPDLYDETITRRWGVDVELATPILSLQILVPSMEREQETQRLEIPSRKIFSSSSPSSSSSSGSTEQQFVEVFDVPKAPTSSSEQQIEDIRITAHEIPPPVSSVEQQEASSDEDGEEREPHIRLNLDDIEFHGNSGEEVISPDSPEMLNPNYEGVSSTGSDEQPKGENEAVYRDRRLVKRQVEITYPSEQMQQTEQVVYRSLGSPHLAQPIKLQMWLDVDSARFGPRSNPQCVRWNSFTNQWTRLGCQTEIPDFDGDFNPAAQQAILVNCSCTHISSYAVIVDVIDPEDIPEPSLLVQITSYSAFLVSLPLLLGVLLALALLRGQQTNSNTIHQNIVLCVFCAELLFFVGMQSRRQLLESEFPCKLTAICLHYFWLAAFAWTTVDCVHLYRMLTEMRDINHGPMGFYFAMGYGAPAIVVGLSVGVRAHEYGNSLFCWLSVYEPVVWWLVGPIAGMSVVNLLILFVSVKAAFTLKDHVLGFGNLRTLLWLSVVSLPLMGVMWVLAVLAASEHSQLLSLLLSGVVLLHALFCLIGYCIINKRVRENLQRTCLRCMGRKVPLLDSSMVVSNSSHNVNAAARPSNFLASGYDTTTRRNIGISASSTTSRSTAKTSSSPYSDGQLRQTSTSTSNYNSASDAPSFLRGFESSTTGRSRGGEEKPSRRQRKDSDSGSETDGRSLELASSHSSDDDESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELNVVQSPQLFPSVNKPVYAPRWSS--QLPDAYLQSPPNIGRWSQDTGSDNEHVHGQAKMTISPNPLPNPDLTDTSYLQQHHNKINMPPSILENIRDAREGYEDSLYGRRGEYPDKYGSYKPPSHYGSEKDYPGGGSGSQTIGHMRSFHPDAAYLSDNIYDKQR---TLGSGYLGAKSESPYLSKDRITPDIYGSRDGHYSLKRQPAYATDSLHSVHSLLKNDYHQQ------------------QQQQQQHHLQDRLSEGSDKNGYHFPYTAEEDHLPARKLS-HTQPPSLHGSQLMQPPGVGLVNDVNNPGLMGRHTLNGGSRHSSRASSPPSTMVAPMQP----------LGPLTSITDTERNIDDDETTV---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : *: * : . :. . : . : . .** . : . . * . ..: . : :. . : : .. ** : :: . . : . . . * . . . : : : : . :. . . * . .:. : : : : . : . : *. *: * * * * . * *::..*::* : *.* * . : **:..*::*** . *.:*. :*:: *: **** *: **:**.* *.. * *.** : :.* * ***:*.** ::. ::**.. * .:: ***** * **::.* * . . *.**.***:*:* . :*** : * *:* *:* . . * :**. *::.***:*** ****:: *.. * ** .. : :: *** *:. *. ::* **.**::.:*:***::*::.:: ***:*: *.* * :**** * *. ** * ::* * **: * * :: ** :***..*:*:.::::** *:*.* *:.: * :: : *:.::. **** . ****. :: * * *:* * ** **::**.:** ***** * * * * .:.** . **.*.:***.* * :* : *:** ****.****:: .* **:::* .******: : *.::*:* * . *********.. *:*:.* **.*: ** * *:*::*:**:*.*** **:*** *::: * *:. :***. :* ** * * *::**:*.* *. :*** **: *.******* * :. * . : *** ***:*::*:* *. ***::* :.: : **.*.*:**** :** : ****:*..:.*** ***:* ** :.* :*: : ****..*.*.::.: : * *** *****.:* * ***:* ** : *.*: *: .: *.: .* :* :: :****: :.: :**:*:*.** . * :.: :.* ***.* :.:**::***: : **** ***:**.*.****:*.* : **: :** :* :** : ** :*:.* * .*.* ::*:**::...* * * :***::* .*:****::* :* ****** **:*::*::. . :.:*:*.:* *:*.. :******* * ::..: *:*::*:.*. * : ::*******:*:**** *: :*::**:*..:: *: * :.***** *: : * ** **** *: *::****:** ***.*.********:* .* ** . * .. :** . .: . *.: :*:* .**: *..*:**.::.:.* ***:: .***:**** ** ***:***: *:: :.:* *: . :* . :***:** *.: * *:. . . : . . : . .* .:*::. . . :.:: ******* :**:*.:* :**.: ::*:**: **:**.* :*: .::*:*** .** * :* * ** *.* * * :**:** *:.*:.* :. * :* *..:* :: .: ** .: :*** .:..*:* * * : : * * . . : * :.**.** :.:. :: . :*: ..:: :. :::*: * :: :*. . . : ****.* * ..* *: :.* ** * . ** *:.* . *: :* * .*: * .* * :.** . . *: . .:** *:* .. .*.:*::.::* ** ****. .****.** :*:..:****.*:*:** **: .. **.****.:** * :* * :*** ** *.:**:*: *..*:**** :**.*:**.**::: ..:***:* :. * ** : * . * ** * * **::**** .* ** *. ** : *::. *:*.:**.. . .: :. *: :: ** *: :* *.*:.*: :** :* :*:: . *.:* * * .*. :::* **:. . ** .*. :* **: : :* : : : : :*:*:. :: : :* **:*::* *. . . ..*. : .. . *. : * : .:.. : ::. * . : :* :.. .. .: * .*: *:: * : **:. **:*: .. * * * . :: ..* * : .::.*::* * : : : :: . .*:. *: . * **. ::* . ** *:. . :.* :::*:: ..:: *. .** ****::::*** *: :*:*** .* *::: *.* **.*:*:*.**:: **:**: .. ***. ***:*::: ::* :.**: : ::* :::: : : . :: : :.. * * *::.::*... : * : ::.* *: : ::* .: :** . .. . ..:* : . *.: .::* .:. : :. * : * : .:: : *. * ****.*: . .. . * **:.::. *. : .. *.. : : * * . *.* :* :...* .: . *.:* * :: . . . . : * . .:.. : *** . . :*.*:*.*.:. . : .: * .: . .:. . *: * . . . : :: : .: * : :*:*: .: * . . .. * :: .. * :. . .* .. : *.:.:.: .. ", "identical_positions": 902, "similar_positions": 987, "identity": "22.37%" }, { "cls_id": "homologset.agr.HGNC:32305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLY5-1", "uniprot_id": "D3ZLY5_RAT", "id": "D3ZLY5-1", "name": "", "aln": "MSIEKMTKVEENLQRAVTLKKTVNRWQNFHTQCLWQMTLDQRRNLYATLRMQDTMEQELALSNKQLLLVRQAALHELFEKEYQQYQQELNRMGKAFYEERL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9D9-1", "uniprot_id": "CP141_MOUSE", "id": "Q9D9D9-1", "name": "Cilia- and flagella-associated protein 141", "aln": "MSAEKMTKLEENLQRAVALKKTVDRWRNFHIHCMWQTTLDQRRNLFAALRMKDTKEQELALSNKQLLVVRQAALHELFEKEYQQYQQELNQMGKAFYEERL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VU69-1", "uniprot_id": "CP141_HUMAN", "id": "Q5VU69-1", "name": "Cilia- and flagella-associated protein 141", "aln": "MSVEKMTKVEESFQKAMGLKKTVDRWRNSHTHCLWQMALGQRRNPYATLRMQDTMVQELALAKKQLLMVRQAALHQLFEKEHQQYQQELNQMGKAFYVERF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *****:**.:*:*: *****:**:* * :*:** :*.**** :*:***:** *****::****:*******:*****:********:****** **:", "identical_positions": 71, "similar_positions": 21, "identity": "70.3%" }, { "cls_id": "homologset.agr.HGNC:32308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQD2-1", "uniprot_id": "D3ZQD2_RAT", "id": "D3ZQD2-1", "name": "Adipolin", "aln": "MWAWGWAAAALLW----LQTAGVRARQELKKPRQLVVRVDSPNITT--SSHEGFPGSIKPPEASGPELSDAHMTWLNFVRRPDDGASRKRCRGRDKKSRGLSGLPGPPGPPGPPGPPGSPGLEVTPEALLQEFQEMLKEAAELRFSG--------IPDSLLPQE--PRQRLVVEAFHCRLKGPVTVDKKTLVELQGFQAPTTQGAFLRGSGLSLSLGRFTAPVSAIFQFSASLHVDHSELQ-GRGRLRTRDTVRVLICIESLCHRHTSLEAVSGLESNSRVFTVQVQGLLYLQSGQYVSVFVDNSSGAVLTIQNGSSFSGMLLGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2Z0-1", "uniprot_id": "ADIPL_MOUSE", "id": "Q8R2Z0-1", "name": "Adipolin", "aln": "MWAWGWAAAALLW----LQTAGAGARQELKKSRQLFARVDSPNITT--SNREGFPGSVKPPEASGPELSDAHMTWLNFVRRPDDGSSRKRCRGRDKKSRGLSGLPGPPGPPGPPGPPGSPGVGVTPEALLQEFQEILKEATELRFSG--------LPDTLLPQE--PSQRLVVEAFYCRLKGPVLVDKKTLVELQGFQAPTTQGAFLRGSGLSLSLGRFTAPVSAIFQFSASLHVDHSELQ-GRGRLRTRDMVRVLICIESLCHRHTSLEAVSGLESNSRVFTVQVQGLLHLQSGQYVSVFVDNSSGAVLTIQNTSSFSGMLLGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T7M4-1", "uniprot_id": "ADIPL_HUMAN", "id": "Q5T7M4-1", "name": "Adipolin", "aln": "MRRWAWAAVVVLLGPQLVLLGGVGARREAQRTQQPGQRADPPNATASASSREGLPEAPKPSQASGPEFSDAHMTWLNFVRRPDDGALRKRCGSRDKKPRDLFGPPGPPG------------AEVTAETLLHEFQELLKEATERRFSG--------LLDPLLPQG--AGLRLVGEAFHCRLQGPRRVDKRTLVELHGFQAPAAQGAFLRGSGLSLASGRFTAPVSGIFQFSASLHVDHSELQ-GKARLRARDVVCVLICIESLCQRHTCLEAVSGLESNSRVFTLQVQGLLQLQAGQYASVFVDNGSGAVLTIQAGSSFSGLLLGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1A5X5-1", "uniprot_id": "ADIPL_DANRE", "id": "A1A5X5-1", "name": "Adipolin", "aln": "MRCWVLAVVTAVLWSQCIPLGWAEGRKVPKRLKEGAPQHTEAFNTT-LSNSEELDGSPK--QVGENQRVDPLGSWMDFVKRP-VGNFPGKCR---KRKRPLPGPPGPPGPPGPQGPPGAPGAEVTQEVLLREFKEMIKEATERRAAVDRPSEPSQLPTALITLEGMTSYRRIEEAFHCKLKGPVVVDKKTLAELQNFQTPPAKGAFLRGTGMDQSTGRFTAPVTGIYQFSANVHIDHTEVKRSKSQLRARDNVRVLICIESLCHRYTSLEMIVGLESNSKIFTVSVHGLLELQAGQYTSIFVDNAAGASITIQNGSDFMGMLLGV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *... : : . . .*: :: :: : . *: *. * : : * :.. : *. :*::**:** * :* *: * * * ***** ** *.**:**:*::***:* * : : .*:. . * : ***:*:*:** ***:**.**:.**:*.::******:*:. : *******:.*:****.:*:**:*:: .:.:**:** * *********:*:*.** : ******::**:.*:*** **:***.*:****.:** :*** *.* *:***.", "identical_positions": 131, "similar_positions": 90, "identity": "40.31%" }, { "cls_id": "homologset.agr.HGNC:32309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B3P4-1", "uniprot_id": "A0A8I6B3P4_RAT", "id": "A0A8I6B3P4-1", "name": "", "aln": "MFLTVKLLLGRRCSLKVSGKESVATLKKLVSQHLQVPEEQQHLLFRGQLLADDKYLSDYS-IGPNASIN-VIMRPQEDVALDKTHQ--TQPLWLQLGQVLDKHFGSKDAKTVLGFLRQEHEERLQRLSLEGLEQLVGQLLAQQQLDELAEEKEAPAVASELQQNDEGEGGG--TGGGGKEEEEKEEAEKGADQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ84-1", "uniprot_id": "UBL4B_MOUSE", "id": "Q9CQ84-1", "name": "Ubiquitin-like protein 4B", "aln": "MFLTVKLLLGRRCSLKVSGKESVATLKKLVSQHLQVPEEQQHLLFRGQLLADDKYLSDYS-IGPNASIN-VIMRPPEDAALDKTHQ--TQPLWLQLGQVLDKHFGAKDAKTVLGFLRQEHEERLQRLSLEALEQLVGQLLAQQQLDELAEEKEAPAVASELEQNNGGGGGGGGTGGEGGGKKEEEEGEE-ADQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N7F7-1", "uniprot_id": "UBL4B_HUMAN", "id": "Q8N7F7-1", "name": "Ubiquitin-like protein 4B", "aln": "MFLTVKLLLGQRCSLKVSGQESVATLKRLVSRRLKVPEEQQHLLFRGQLLEDDKHLSDYC-IGPNASIN-VIMQPLEKMALKEAHQPQTQPLWHQLGLVLAKHFEPQDAKAVLQLLRQEHEERLQKISLEHLEQLAQYLLAEEPHVEPAGERELEAKARPQSSCD---------------MEEKE--EAAADQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEC8-1", "uniprot_id": "Q9VEC8_DROME", "id": "Q9VEC8-1", "name": "Ubiquitin-like domain-containing protein", "aln": "MQITIKVLKGKDCTIEVAPTSTILEVKHQIEAELQISATNQKLLLLGRPLNNEQTIASYPNIKEGTKLNLVVIKPCLRDSILRGFR---------------KHYSEPLAERMTNEFMADFERKINEQSLDDLERLADSIVNRAAT------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :*:*:* *: *:::*: .:: :*: :. .*::. :*:**: *: * ::: ::.* * .:.:* *:::* :: . .: **: *: : : :.*.:::. **: **:*. :: . ", "identical_positions": 28, "similar_positions": 58, "identity": "14.51%" }, { "cls_id": "homologset.agr.HGNC:3231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYP2-1", "uniprot_id": "CELR2_RAT", "id": "Q9QYP2-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYILRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSG----ELTALVDLDYE-DRPEYILVIQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELRLSRALDNNRPLEAIMSVLVSDGVHSVTAQCSLRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTG----DYCETEVDLCYSRPCGPHGHCRSREGGYTCLCRDGYTGEHCEVSARSGR-CTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPFCQVTTRSFPARSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVSVDGCDTGVALRFGAMLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRHFVGCMKNLQVDSRHVDMADFIANNGTVPGCPTKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQRFLGSSLVAWHGLSLPISQPWHLSLMFRTRQADGVLLQAVTRGRSTITLQLRAGHVVLSVEGTGLQASSLRLEPGRANDGDWHHAQLSLGASGGPGHAILSFDYGQQKAEGNLGPRLHGLHLSNMTVGGVPGPASSVARG--FRGCLQGVRVSETPEGVSSLDPSRGESINVEPGCSWPDPCDSNPCPTNSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEHQSACTRKPSAPHGYICECLPN-YLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPSSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCDEHRG-WLPPNLFNCTSVTFSELKGFAERLQRNESGLDSGRSQRLALLLRNATQHTSG-----------------------------------------------------YFGSDVKVAYQLATRLLAHESAQRGFGLSATQDVHFTENLLRVGSALLDAANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAG---TKLPRYEALRGERP-----------------------------PDLETTVILPESVFREMPPMVRSAGPGEAQETEELARRQRRHPELSQGEAVASVIIYHTLAGLLPHNYDP------------------------------DKRSLRVPKRPVIN--TPVVSISVHDDEELLPRALDKPVT----------------------------------------------------------------------------------------------------------------------VQFRLLETEERTKPICVFWNHSILVSGTG---------------GWSARGCEVVFRNES-----------HVSCQCNHMTSFAVLMDVSRRENGE--ILPLKTLTYVALGVTLAALMITFLFLTLLRALRSNQHGIRRNLTAALGLAQLVFLLGIN----QADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNASPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAGPVAFAVSMSVFLYILSARASCAAQRQGFEKKGPVSGLRSSFTVLLLLSATWLLALLSVNSDTLLFHYLFAACNCVQGPFIFLSYVVLSKEVRKALKFACSRKPSPDPALTTKSTLTS-------------------------------SYNCPSPYADGRLYQPYGDSAGSLHSASRSGKSQPSYIPFLLREESTLNPGQVPPGLGDPS---------GLFMEGQAQQHDPDTDSDSDLSLEDDQSGSYASTHSSDS---------------------------------------------EEEEEE----AAFPGEQGWDSLLGPGAERLPLHSTPK------------------------------------------------------------------DGGPGSGKVPWPGDFGTTTKENSGSGPLEERPRENGDALTREGS-----------------------LGPLPGPSTQPHKGILKKKCLPTISEKSSLLRLPLEQGTGSSRG------------------STASEGSRNGPPPRPPPRQSLQEQLNGVMPIAMSIKAGTVDEDSSGSEFLFFNFLH------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0M0-1", "uniprot_id": "CELR2_MOUSE", "id": "Q9R0M0-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 2", "aln": "----------------------------------------------------------------------------------------------------MRSRAASAPLPTPLLPLLLLLLLLP----------PSPLLGDQVGPCRSLGSGGRSSSGACAPVGWLCPASASNLWLYTSRCRESGIELTGHLVPHHDGLRVWCPESGAHIPLPPSSEGCPWSCRLLGIGGHLSPQGTLTLPEEHPCLKAPRLR----------------CQSCKLAQAPG----------------------------------------------------LRAGEGSPEESLGGRRKRNVNTAPQFQPPSYQATVPENQPAGTSVASLRAIDPDEGEAGRLEYTMDALFDSRSNHFFSLDPITGVVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGAGGS------PSDAFEIDPRSGVIRTRGPVDREEVESYKLTVEASDQGRDPGPR-SSTAIVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG---APVLRVTASDRDKGSNALVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRIRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYSLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTILDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDG-TRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIP-------QFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSG----ELTALVDLDYE-DRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELRLSRALDNNRPLEAIMSVLVSDGVHSVTAQCSLRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTG----DYCETEVDLCYSRPCGPHGRCRSREGGYTCLCLDGYTGEHCEASTHSGR-CTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPFCQVTTRSFPARSFITFRGLRQRFHFTLALSFATKERNGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVSVDGCDTGVALRFGAMLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRHFVGCMKDLQVDSRHIDMADFIANNGTVPGCPTKKIVCDSSICHNGGTCVNQWNAFSCECPLGFGGKSCAQEMANPQRFLGSSLVAWHGLSLPISQPWHLSLMFRTRQADGVLLQAVTRGRSTITLQLRAGHVVLSVEGTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQKAEGNLGPRLHGLHLSNITVGGVPGPASGVARG--FRGCLQGVRVSETPEGISSLDPSRGESINVEPGCSWPDPCDSNPCPTNSYCSNDWDSYSCSCVLGYYGDNCTNVCDLNPCEHQSVCTRKPNTPHGYICECLPN-YLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCDEHRG-WLPPNLFNCTSVTFSELKGFAERLQRNESGLDSGRSQRLALLLRNATQHTSG-----------------------------------------------------YFGSDVKVAYQLATRLLAHESAQRGFGLSATQDVHFTENLLRVGSALLDAANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAG---TKLPRYEALRGERP-----------------------------PDLETTVILPESVFREMPSMVRSAGPGEAQETEELARRQRRHPELSQGEAVASVIIYHTLAGLLPHNYDP------------------------------DKRSLRVPKRPVIN--TPVVSISVHDDEELLPRALDKPVT----------------------------------------------------------------------------------------------------------------------VQFRLLETEERTKPICVFWNHSILVSGTG---------------GWSARGCEVVFRNES-----------HVSCQCNHMTSFAVLMDMSRRENGE--ILPLKTLTYVALGVTLAALMLTFLFLTLLRALRSNQHGIRRNLTAALGLAQLVFLLGIN----QADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNASPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSVYDTLIWSFAGPVAFAVSMSVFLYILSARASCAAQRQGFEKKGPVSGLRSSFTVLLLLSATWLLALLSVNSDTLLFHYLFAACNCVQGPFIFLSYVVLSKEVRKALKFACSRKPSPDPALTTKSTLTS-------------------------------SYNCPSPYADGRLYQPYGDSAGSLHSASRSGKSQPSYIPFLLREESTLNPGQVPPGLGDPS---------GLFLEGQAQQHDPDTDSDSDLSLEDDQSGSYASTHSSDS---------------------------------------------EEEEEE----AAFPGEQGWDSLLGPGAERLPLHSTPK------------------------------------------------------------------DGGPGSGKVPWLGDFGTTTKENSGSGPLEERPRENGDALTREGS-----------------------LGPLPGPSTQPHKGILKKKCLPTISEKSSLLRLPLEQGTGSSRG------------------SSISEGSRHGPPPRPPPRQSLQEQLNGVMPVAMSIKAGTVDEDSSGSEFLFFNFLH------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCU4-1", "uniprot_id": "CELR2_HUMAN", "id": "Q9HCU4-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 2", "aln": "----------------------------------------------------------------------------------------------------MRSPATGVPLPTPPPPLLLLLLLLL----------PPPLLGDQVGPCRSLGSRGRGSSGACAPMGWLCPSSASNLWLYTSRCRDAGTELTGHLVPHHDGLRVWCPESEAHIPLPPAPEGCPWSCRLLGIGGHLSPQGKLTLPEEHPCLKAPRLR----------------CQSCKLAQAPG----------------------------------------------------LRAGERSPEESLGGRRKRNVNTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGS------PSEVFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGPR-STTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG---APVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDG-TRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIP-------QFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSG----ELTALVDLDYE-DRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTG----DYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGR-CTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQVTTRSFPAHSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQHFLGSSLVAWHGLSLPISQPWYLSLMFRTRQADGVLLQAITRGRSTITLQLREGHVMLSVEGTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGPAGGVARG--FRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPN-YLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCDEHRG-WLPPNLFNCTSITFSELKGFAERLQRNESGLDSGRSQQLALLLRNATQHTAG-----------------------------------------------------YFGSDVKVAYQLATRLLAHESTQRGFGLSATQDVHFTENLLRVGSALLDTANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAG---AKLPRYEALRGEQP-----------------------------PDLETTVILPESVFRETPPVVRPAGPGEAQEPEELARRQRRHPELSQGEAVASVIIYRTLAGLLPHNYDP------------------------------DKRSLRVPKRPIIN--TPVVSISVHDDEELLPRALDKPVT----------------------------------------------------------------------------------------------------------------------VQFRLLETEERTKPICVFWNHSILVSGTG---------------GWSARGCEVVFRNES-----------HVSCQCNHMTSFAVLMDVSRRENGE--ILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSNQHGIRRNLTAALGLAQLVFLLGIN----QADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAGPVAFAVSMSVFLYILAARASCAAQRQGFEKKGPVSGLQPSFAVLLLLSATWLLALLSVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRKALKLACSRKPSPDPALTTKSTLTS-------------------------------SYNCPSPYADGRLYQPYGDSAGSLHSTSRSGKSQPSYIPFLLREESALNPGQGPPGLGDPG---------SLFLEGQDQQHDPDTDSDSDLSLEDDQSGSYASTHSSDS---------------------------------------------EEEEEEEEEEAAFPGEQGWDSLLGPGAERLPLHSTPK------------------------------------------------------------------DGGPGPGKAPWPGDFGTTAKESSGNGAPEERLRENGDALSREGS-----------------------LGPLPGSSAQPHKGILKKKCLPTISEKSSLLRLPLEQCTGSSRG------------------SSASEGSRGGPPPRPPPRQSLQEQLNGVMPIAMSIKAGTVDEDSSGSEFLFFNFLH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V5N8-1", "uniprot_id": "STAN_DROME", "id": "Q9V5N8-1", "name": "Protocadherin-like wing polarity protein stan", "aln": "MQTREFPQRPLGLLLVLLVVLLQSSLIKSYLIIVHEDTPPGTVIFNASVYKLGSERHYKINAHKSANFVHHLVSVNHKDGQIQLRKALKCDGIYYPNLFTFYVDSTSNRLRSIDYYSLPVRIFVSGHSCNEDRRIEQELHHHHYEEEDNTGYSKRRRRRSTQEMIQLNGNQLEEVFRQNSTEFRAGDLIFGDSFDNEMRHRILSRKRRAVGSPDPLHLQPALHRRISDAKQWISETYASYAIHTTDKWNQICLRRSQFINSLNAFLPRSVCQHCKVSFLDVNDERFAIEHQSRDLVASRDVCIAESMWKVSITFNIRCDRRDIVDSDHRLKIVYHHQEFNDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDS---PVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTT-QLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFN----NFRDHFPSGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAFLSPLLNFFLDGLAAIIPCPKEHIFVFSIQDDTDVSS-RILNVSFSARRPD--VSHEEFYTPQYLQERVYLNRAILARLATVEVLPFDDNLCVREPCLNFEECLTVLKFGNASEFIHSDTVLFRPIYPVNTFACSCPEGFTGSKEHYLCDTEVDLCYSDPCQNGGTCVRREGGYTCVCPSTHTGQNCETGVGHLRPCPSETCEGGLSCLSNYPS------SQPPPYTATCELRARAFGRNSFLTFESLKQRHRFNLKLRFATVQENGLLLYNGRYNELHDFIALEIHEGHVSFSFSLGDHSERISVIQEAKVSDGKWHQVEVVYLNRSVT----LVLDNCDTAIALSGQLGDRWSCANRTTLKLDKRCSLLTET---CHRFLDLTGPLQVGGLPRIPAHFPVTNRDFVGCISDLRIDDRFVDLNSYVADNGTLAGCPQKAPLCQSEPCFNGGTCREGWGTYSCECPEGYAGNSCQDNIPAPWRFSGDGSLSFNPLLRPIQLPWTTSFSLRTRQKEAFLLQIQIGQNSSAAVCLRQGVLYYIFDGE-----PMYLAGAFLSDGEWHRVEIRWQQGS---EIHFSVDYGQRSGSVPMSQKVQGLYVGKIVMGSPDGSIGAVPEASPFEGCIQDVRIGAG----QSVLSRPTIRENVEDGCESRAQCP-DHCPNHSSCQSSWDLSTCECDSGYVGTDCAPICTVRPCASG-VCRANTSLPRGYDCECNSSSRHGDYCEKELQQPCPGGWWGERVCGPCRCDLAQGYHPDCNKTTGQCYCKTNHYQPPNETACLSCDCYSIGSFSGACNPLTGQCECREGVIGRRCDSCSNPYAEVTLSGCEVVYDACPRSFAGGVWWPRTPLGGVAIEGCPPPARGKGQRSCDVQSGSWNTPDMYNCTSEPFVELRRQLSQLEKLELELNSFVAIKMAEQLRKACEAVDRRGASKDQKISGNGRPNRRYKMESSFLLSNGGNVWSHELEMDYLSDELKFTHDRLYGADLLVTEGLLQELINYELMQSGLNLSHSQDKYFIKNLVDAASVILDRKYEAEWRRATELIQRGPDDLVDAFNKYLVVLARSQHDTYTSPFEIVQPNMALGLDIVTTESLFGYEPEQLSEYHRSKYLKPNAFTTESVVLPDTSGFLQHSARQRPVISFPKYNNYILDRRKFDQHTKVLVPLEMLGITPPESDEISQSGRRGSSHDHRAIVAYAQYKDVGQLLPDLYDETITRRWGVDVELATPILSLQILVPSMEREQETQRLEIPSRKIFSSSSPSSSSSSGSTEQQFVEVFDVPKAPTSSSEQQIEDIRITAHEIPPPVSSVEQQEASSDEDGEEREPHIRLNLDDIEFHGNSGEEVISPDSPEMLNPNYEGVSSTGSDEQPKGENEAVYRDRRLVKRQVEITYPSEQMQQTEQVVYRSLGSPHLAQPIKLQMWLDVDSARFGPRSNPQCVRWNSFTNQWTRLGCQTEIPDFDGDFNPAAQQAILVNCSCTHISSYAVIVDVIDPEDIPEPSLLVQITSYSAFLVSLPLLLGVLLALALLRGQQTNSNTIHQNIVLCVFCAELLFFVGMQSRRQLLESEFPCKLTAICLHYFWLAAFAWTTVDCVHLYRMLTEMRDINHGPMGFYFAMGYGAPAIVVGLSVGVRAHEYGNSLFCWLSVYEPVVWWLVGPIAGMSVVNLLILFVSVKAAFTLKDHVLGFGNLRTLLWLSVVSLPLMGVMWVLAVLAASEHSQLLSLLLSGVVLLHALFCLIGYCIINKRVRENLQRTCLRCMGRKVPLLDSSMVVSNSSHNVNAAARPSNFLASGYDTTTRRNIGISASSTTSRSTAKTSSSPYSDGQLRQTSTSTSNYNSASDAPSFLRGFESSTTGRSRGGEEKPSRRQRKDSDSGSETDGRSLELASSHSSDDDESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELNVVQSPQLFPSVNKPVYAPRWSSQLPDAYLQSPPNIGRWSQDTGSDNEHVHGQAKMTISPNPLPNPDLTDTSYLQQHHNKINMPPSILENIRDAREGYEDSLYGRRGEYPDKYGSYKPPSHYGSEKDYPGGGSGSQTIGHMRSFHPDAAYLSDNIYDKQRTLGSGYLGAKSESPYLSKDRITPDIYGSRDGHYSLKRQPAYATDSLHSVHSLLKNDYHQQQQQQQQHHLQDRLSEGSDKNGYHFPYTAEEDHLPARKLSHTQPPSLHGSQLMQPPGVGLVNDVNNPGLMGRHTLNGGSRHSSRASSPPSTMVAPMQPLGPLTSITDTERNIDDDETTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* *::**:*.* *. **** :** *.******* * **.*: **. ***:*::*:* * *****: * :.. * **.*:::.*** :** : ****.** : * * ***** ** :.:** : : ****.**.* .*:: ::* ****:* .*..: * *****.** : *.*: *: .:.*.* .* :* ::.:**** * .: **::*:*.** . * :.: : * ***.*** :*:::** * . **.* ***:**.*.*:**.* * : **: .*: **:*:* * ** *:.* * * *.* ****::...* * * :**::** :*:*:**::*: * ******.:*::.:** :. * :*:.**.:* ***... :*****:*. :* . * ..: ****:****::*: ::: .*******:*:**** *: .*::**:*..:: ** *.:******:**. : * ** **** *:******** ** * * *******:* . :**::**... * *.. .*:.* :*:. . .. .. *:: :*:* .**:**..*:**.:*.* * *** :.:********:** ***:***: : :*.::** *: : :* : . ****:** *:: * *:.: * . .: :*: * . * * *.: .. * .:: ******* :**:* :* *** *.****: :*::*.*.:*: .::*:***:.*** * :*:*. *.***** : *.::***** *:.*:** :::. * :* *.. :::: * **. ** *: :**** :..*** .*: :: ** * : .:* .: * . .**:**:.:: .. . :*.****: .. :. :::**::.::.:*. *. ..*... *.**:*.**:. .*: . *** **. * : ** :* *...** :*.* ** * :*: :* :.** .* :.. *:** *** .. * ***..::**** ****. .****.**:::*:.******:*:*:** ***:**...:** ****. **:* .*:* *** *: *****:** *.**:**** .**** **:***:: .*:***** :* * ** : *.. * ** : * * .*:::**** .* **: .:*:: * *:* : ::* **:* : . :*:*: *: * .*: :* * *:.** :** :* :**: ..*.:** : .*. : *. *:: :: * .**:. :.** *** ** **:.:.: : . .: * :*..*. : :* *. :. :: ... :. :* * : .: :. *: . : .*:.: *: :. ***. ** :.: *.:*.* ::. :* * * . *: : ..:* * : * :* * : . ::** : .: : * *: **:. : : . *.*.*.*::*:**::*: *: * :: :* *: *:*. *: .:: *:*** ::*.: *::*:. .: *:*:*::*:: : *.*.: ** **:::*.:*:*: ::.:**** ***:**:* .** **: :*:*.**::.**:**: .. ***. *****:*:.::* :.**:* :.::: :::.:*: : : : : . : * *.. * *:.. *:**:*:....: *: *:: ::. * ::.* ::.*.**: *: :* * . . .* .* :.* : . .* : .**.*. *:* *. ...* * :** .: ..*: * .*. . :*: : .. .**.* * .**:: ** *.: : :. . :. : * *. * ::.: ..* .**.*. . .* . : *.. ::* .* ::. * * ...: * *: .::.. :* . **.:. * . * *. ** .* :::*. :. * ..* .*. . ", "identical_positions": 753, "similar_positions": 719, "identity": "20.82%" }, { "cls_id": "homologset.agr.HGNC:32310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80YR9-1", "uniprot_id": "R12BA_MOUSE", "id": "Q80YR9-1", "name": "RNA-binding protein 12B-A", "aln": "-MAVVIRLLGLPFIAGPVDIRHFFKGLTIPDGGVHIIGGKVGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKVEMQKTIEMKR-----------------TARVGRGRPGSGASGVGNVYHFSDALKEEESYSGYGS--------SVNRDAGFHTNGTGL--------------------------DLRPRKTRPLKAENPYLFLRG----LPYLVNEDDVRVFFSGLCVDGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGTATEGGD---TPRMRSEEHSPSRRINGRHFRKRSHSKSPR-ARSRSP------------LGFYVHLKNLSLNTNKRDLRNLFRDTDLTNDQ-IKFVYKDERRTRYAFVMFKNQKDYNTALGLHKTVLQYRPVLIDPVSRKEMVRIIECYEKKRPESLEKERPGRVSQKYSQEGFS----GSGQKLCIYIRNLPFDVTKGEVQKFFADFSLVEDDIYLLCDDKGVGLGEALVRFKSEEQAMKAERLNRQRFLGIEVLLRLISEEQ-----MQEFGVKSSWLSNERTQACSRSHDGDDCSCLFDLKDPSSC--SFGQSESLRYHPKDLRKMGHFKHPQGYFRQSDRRSPEDFRHS--------------PEDYRHPWEEHTS------------------------HSREEDWRLPL-EDWKWSQEDDFRQCHEKDRRQL-----------------------------RSPWEEDFRRPSQ----------------------------------------------------------------------------------------EHFRRSYQEHIRQPPEEHFRRSREEDFRHVADEDFRQASDEDFRTS---------QEDLRYPTDEDFRRVSVEDLREVPEKDLRLPKNFRSPGEEFWTPP-DFRGQHPFGNFDHLQGGKFDFEKYKFGSF-----PDAKVTSDLNLNCVSDKIIPVKISNLPFKANASEILDFFHGYKVIPDSVSLQYNEQGLPIGEAIVAMTNYNEALAAVKDLSGRPVGPRKVKLSLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66JV4-1", "uniprot_id": "R12BB_MOUSE", "id": "Q66JV4-1", "name": "RNA-binding protein 12B-B", "aln": "-MAVVIRLLGLPFIAGPVDIRHFFKGLTIPDGGVHIIGGKVGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKVEMQKTIEMKR-----------------TARVGRGRPGSGASGVGNVYHFSDALKEEESYSGYGS--------SVNRDAGFHTNGTGL--------------------------DLRPRKTRPLKAENPYLFLRG----LPYLVNEDDVRVFFSGLCVDGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGTATEGGD---TPRMRSEEHSPSRRINGRHFRKRSHSKSPR-ARSRSP------------LGFYVHLKNLSLNTNKRDLRNLFRDTDLTNDQ-IKFVYKDERRTRYAFVMFKNQKDYNTALGLHKTVLQYRPVLIDPVSRKEMVRIIECYEKKRPESLEKERPGRVSQKYSQEGFS----GSGQKLCIYIRNLPFDVTKGEVQKFFADFSLVEDDIYLLCDDKGVGLGEALVRFKSEEQAMKAERLNRQRFLGIEVLLRLISEEQ-----MQEFGIKSSWLSNERTQACSRSHDGDDCSCLFDLKDPSSC--SFGQSESLRYHPKDLRKMGHFKHPQGYFRQSDRCSPEDFRHS--------------PEDYRHPWEEHTS------------------------HSREEDWRLPL-EDWP--QEDDFRQCHEKDHRQL-----------------------------RSPWEEDFRRPSQ----------------------------------------------------------------------------------------EHFRRSYQEHIRRPPQEHFRRSREEDFRHVADEDFRQASDEDFRIS---------QEDLRYPTDEDFRRVSVEDLREVPEKDLRLPKNFRSSGEEFWTPP-DFRGQHPFVNFDHLQGGKFDFEKYKLENF-----HDGKFVPDLKFNCGSGGIIRVMISNLPFKANANEILDFFHGYKVIPDSVSIQYNEEGLPLGEAIVSMTNYNEALSAVKDLSGRPVGPRKVKLSLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZM54-1", "uniprot_id": "D3ZM54_RAT", "id": "D3ZM54-1", "name": "", "aln": "-MAVVIRLQGLPFIAGPVDIRHFFKGLTIPDGGVHVIGGKAGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKVEMQKTIDMKR-----------------SARVGRGRPGPEASGVGNMYHFIDALKEEERYSGYGS--------AVNPDAGFHINGTGL--------------------------DLRPRKTRPLKAENPYLFLRG----LPYLVNEDDVRVFFSGLCVDGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGTASKGGD---TLHKRSEEHSPSRRLNDRYFWKRSRSKSPR-TRSRSP------------LGFYVHLRNLSLHTNKRDLRYLFRDTDLSNDQ-IKFLYKDDRRTRYAFVMFKNQKDYNTALGLHKTVLQYRPVLIDPISRKEMVKIIECYEKKRPESLEEERPGRVSQKYSEEGFP----GSGQKLCIYIRNLPFDVTKGEVQKFFADFSLVEDDIYLLSDDKGIGLGEALVRFKSEEQAMKAERLNRQRFLGTEVLLRLISEEQ-----MQEFGVNFSWMSNEKTQACSRSHDGDDCSCLFDLKDPLATGQSFGQSESIRYQPKDFRKMGHFKHPRGYFQQSDRHSPEDFRHS--------------PEDFGHPREEHSR------------------------RSREEDWRRPL-EDWKWPLEDDFRQSREKDCRQLPEKDF------------------------RCPWEEDFRRPSQ----------------------------------------------------------------------------------------EHFRRSYQEHIRQPPHEHFRYSREEDSRHVADEDFRYPADEDFRTS---------QEDLRCPTDEDFRQVCLEDHREVPEGDLRRSDKFRLPGEDFWTSS-DFRGHHPFVNFGHLEGGKFDFGKYNIGSF-----SEAKVTSDLNLSCRSGGIIPVKISNLPFKANSNEILDFFHGYKVIPGSVSLQYNEQGLPIGEAIVAMTNYNEALAAVKDLSGRPVGPRKVKLSLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IXT5-1", "uniprot_id": "RB12B_HUMAN", "id": "Q8IXT5-1", "name": "RNA-binding protein 12B", "aln": "-MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKAEMQKTIEMKR-----------------TDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGS--------SINQDAGFHTNGTGHG-------------------------NLRPRKTRPLKAENPYLFLRG----LPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGD---VLR-RSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSP------------LGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQ-IRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGN------SGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQ-----IQEFGVNFSVMSSEKMQARSQSRERGDHSHLFDSKDPPIY--SVGAFENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLPDNFRPPGEDFRSPPDDFRSHRPFVNFGRPEGGKFDFGKHNMGSF-----PEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDLNDRPVGPRKVKLTLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6E2-1", "uniprot_id": "E7F6E2_DANRE", "id": "E7F6E2-1", "name": "", "aln": "-MAVVIRLQGLRVTAGSEDIRNFFTGLRIPDGGVHIIGGELEEAFIIFASDEDARRAMSRSGGCIKGSTVNLFLSSKSEMQSVLEESTRRSE------------FKNRAMYKEPVKRASAEQGPLPFSKDTRPDVRRADHPE--------MRGRPASSTFSEARR-----------------------------QRDGDAPERAEVYLKLTG----MPFSATKDNVHNFFAGLKVDDILFLKNPRGMFSGNSMVRFTTKEDAIEGLKRDRQYMGSRYIQITRCTEEEWLKEGG-LIVAAD---MRKRTPVERVRSR--SPISYRSRS--------RSPSH------------EEYCIMFENLPPLVEKRDVRVFLQPVALKDDQIIIFSSKKDDKSKSAVVVFRSLTDYCAGLAHNKEMMYNKVVYVSPISKEKMVTMLESSIDARGEEKGSRRSAEASQ---SQRNT----PDSQLRCLYVRNLPFDVRKVEIMDFFHGYALTEDRVILLRDERGAGLGEALVIFQTEKEAMTGQSLNGQRFLGSEVMLKCITMSQ-----MAQFGVNDQPMVS----------------------------------------------------PQERNFQERNFQDRNFQDR--------------------------------------------------------NFQ---------------------------------------------------------------------------------------------------------------------------------------------------------------DRNFQE--RNFQERNFQERNFQD-RNFQDRNFQ---DRNFEER-------------------NFQRN------EVFNDGPGFINNQMPQG-DFEMLP---NMHQGYGGHEHFEP---NFGPGPDGNG-----RQHYEPPDAQFDAP----TCVKLVNLPSQIRIEEIYDFCYGYRVIPGSASLLFDRNGAPKRSATIAFDNHREALVAVRELNGRPIGTRKIQVFIL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T5C1-1", "uniprot_id": "A0AB32T5C1_DANRE", "id": "A0AB32T5C1-1", "name": "", "aln": "MTVVVLRLQGLNTEAGSEDIRRFFHGLHIPEGGVHIIGGEMGEAFIIFKTEREGQLAMRYSGKTLKGSSVSLHISSVAELKRKMESRLKKPKPTE--------LETNVVPSSPTDTNAALLLSLMGAIYGLHSNNKDNQQGQ--------TQQTPGNVNQNSPEMQTWPLTGKQMNTDAQHSLNHELASTEQQTGRGENLNLSKPGYLRLYG----FPDCVAKQEIFQFLRGLPVLEVITKVR--LQLGWCCLVKLASFSDAEEGLKYSHRKFKEFNVEVRLAHEKMWTDAVEESKNCTQ---NLKPHSSSEQNEANNNRNAVRAFTNKRIAEEQPSPGSPKKYCRNDPSPQKEYSVIVNNLSRNITKTEIKNIFGCHAIQNYRIKHLLNKWGERTSTAFITFDNSEDQASAMKMNGMNVGLKNIEVLSITKEEILDILSKNRFVKSWRPPPYGNTHLSMS-----------------CIYARNFPADVRKEEVKGFFMPYNIGDDAVRLLVDNQGNGIGEAIVEFRFQNIAKQAQRLHGKYFMGAKILLTCITHQQ-----MEKILGKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0D6-1", "uniprot_id": "Q9W0D6_DROME", "id": "Q9W0D6-1", "name": "RRM domain-containing protein", "aln": "-MSVIIRLQNLPWTANARDIRNFFSGLSIPEGGVHIIGGEMGDAFIAFSTDEDARCAMLKDREKLMEIQVRLLLSSRAEMQKVIETARKAASAQAPVSVPVPMPVVVPVTAAKVAGPAAPLPPIIGGLNTFLGQGQVKGVATGTVPSFLTYQQQAGITLSDVTGRRSRSRSSSSDDSDRERERDRQRERERGRKRRSDRLDKSQERELKMVAGGGALPSPWAQPPQNQLPAVGLGLNMGLNLNLPQIPSLQSYTTSTTTTNVTNNYNLEPSATSVQLLTALQQVSSGSAAPAQPSKSESEPIAFASVNPYAQMYPQLFQQQQMLLQQQQTQAKVSPTMGGSPGGGSTPQVVADTCYIRMSGMCQNTSYSDIRKYFQGMYIPHNG-IKIMMVNGSRTGVAYVEFSRVSSAQKAVQRNNTMFRDRLIQIVPVGDDEFEMAEERASRQGQDGSRSHGNHNGGDRGERGGGAPVPVPRPVTNVLYIEDLPQTTTEQDIMKMFS-ASYTVVDILLSPSPKNRRESVAFVLFAREAEADSALQDTSKHYIGFRQLRVRSSSEEDMQNAKEKQRRANEQLLKEEADQREELLKDQQRRQKQQQQENENIQANRFAADPRRRQAEDQQQQQQMNMGPNFNSNMSPNMMAPFVNGGNMPFHMPPLQQNGVNNFPFNMNNNYNYNGNSNGNGPNYPNDNGGAGVIQRPRQEDVFVRVHNCEYATRANDLGELFSLEHLRIEHIEQLFNERNQS-----------------SGEFIVEFSDPAS--------------------------------------------------------------------------------------CKLAIREFHNRRFRGRGLRVVAITPQEIADRMKKPFMDYLPGGNGPRKAETNNANDGAGGNKASAQPSRRRGPSRFDKPQEQPSQQQDRPLSLEREDNSSTSSNAPVKQHFNPFARPDPPLSSSSLSPSNQGQVKPTSPVPVPTSIIPDKFNRPGCVVAMRNVPFKAELKDIMRFFSDYKLSPDDIIRRFNDEGKPTGDTRVAFESPSEARSAFESRRKKQIFNRTVYLDII", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::** .* *.. ***.** ** **:****:***: :*** * ::.:.: *: . : * * :** *:: :: . :: : . . . * * : . :* : : : . . . . :: :. . : : .. : . . . : . : . .: ::: : : . : :: * : * . .: : . : : : .: .:: . . :* .::* . : :: :* : * . :. . *:* * : * . : ::* . : : : : ", "identical_positions": 45, "similar_positions": 110, "identity": "4.12%" }, { "cls_id": "homologset.agr.HGNC:32311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7A3-1", "uniprot_id": "MBOA4_MOUSE", "id": "P0C7A3-1", "name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "aln": "--------MDWLQLFF-LHPLSFYQGAAFPFALLFNYLCI---LDTFSTRARYLFLLAGGGVLAFAAMGPYSLLIFIPALCAVALVSFLSPQEVHRLTFFFQMGWQTLCHLGLHYTEYYLGEPPPVRFYITLSSLMLLTQRVTSLSLDICEGKVEAPRRGIRSKSSFSEHLW----DALPHFSYLLFFPALLGGSLCSFRRFQACVQRSSSLYPSISFRALT------------------WRGLQ-----ILGLECLKVALRSAVSAGAGLDDCQRLECIYLMWSTAWLFKLTYYSHWILDDSLLHAAGFG-AEAGQGPGEEGY--VPDVDIWTLETTHRISLFARQWNRSTALWLRRLVFRKSRR-------WPLLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHT------FANVCIRSWPLRLLYRALTWAHTQLIIAYIMLAVEGRSLSSLCQLCCSYNSLFPVMYGLLLFLLAERKDKRN--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1Q005-1", "uniprot_id": "MBOA4_RAT", "id": "B1Q005-1", "name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "aln": "--------MDWLQFFF-LHPVSLYQGAAFPFALLFNYLCI---TESFPTRARYLFLLAGGGVLALAAMGPYALLIFIPALCAVAMISSLSPQEVHGLTFFFQMGWQTLCHLGLHYKEYYLCEPPPVRFYITLSSLMLLTQRVTSLSLDISEGKVEAAWRGTRSRSSLCEHLW----DALPYISYLLFFPALLGGSLCSFQRFQACVQRPRSLYPSISFWALT------------------WRGLQ-----ILGLECLKVALRRVVSAGAGLDDCQRLECIYIMWSTAGLFKLTYYSHWILDDSLLHAAGFG-SEAGQRPGEERY--VPDVDIWTLETTHRISLFARQWNRSTAQWLKRLVFQRSRR-------WPVLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHT------FANGCIRSWPLRLLYRSLTWAHTQIIIAYVMLAVEGRSFSSLCRLCCSYNSIFPVTYCLLLFLLARRKHKCN--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96T53-1", "uniprot_id": "MBOA4_HUMAN", "id": "Q96T53-1", "name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "aln": "--------MEWLWLFF-LHPISFYQGAAFPFALLFNYLCI---MDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVC----KALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALS------------------WRGLQ-----ILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFG-PELGQSPGEEGY--VPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRA-------WPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHS------FANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1Q006-1", "uniprot_id": "MBOA4_DANRE", "id": "B1Q006-1", "name": "Membrane-bound ghrelin O-acyltransferase mboat4", "aln": "-------MIDLLWISSDGHPQLFYQFINIPFAFLFHCLSS---QGHLSIINRYVYLAMGGFMLAIATMGPYSSLLFLSAIKLLLLIHYIHPMHLHRWILGLQMCWQTCWHLYVQYQIYWLQEAPDSRLLLAISALMLMTQRISSLSLDFQEGTISNQS------------------ILIPFLTYSLYFPALLGGPLCSFNAFVQSVERQHTSMTSY-LGNLT------------------SKISQ-----VIVLVWIKQLFSELLKSATFNIDSVCLDVLWI-WIFSLTLRLNYYAHWKMSECVNNAAGLG-VYFHKHSGQTSWDELSDGSVLVTEASSRPSVFARKWNQTTVDWLRKIVFNRTSR-------SPLFMTFGFSALWHGLHPGQILGFLIWAVTVQADYKLHR------FSHPKLNSLWRKRLYVCVNWAFTQLTVACVVVCVELQSLASVKLLWSSCIAVFPLLSALILIIL----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08548-1", "uniprot_id": "ALE1_YEAST", "id": "Q08548-1", "name": "Lysophospholipid acyltransferase", "aln": "MYNPVDAVLTKIITNYGIDSFTLRYAICLLGSFPLNAILKRIPEKRIGLKCCFIISMSMFYLFGVLNLVSGFRTLFISTMFTYLISRFYRSKFMPHLNFMFVMGHLAINHIHAQFLNEQTQTTVD-----ITSSQMVLAMKLTSFAWSYYDGSCTSESDFKDLTEHQKSRAVRGHPPLLKFLAYAFFYSTLLTGPSFDYADFDSWLNCEMFRDLPESKKPMRRHHPGERRQIPKNGKLALWKVVQGLAWMILSTLGMKHFPVKYVLDKDGFPTRSFIFRIHYLFLLGFIHRFKYYAAWTISEGSCILCGLGYNGYDSKTQKIRWDRVRNIDIWTVETAQNTREMLEAWNMNTNKWLKYSVYLRVTKKGKKPGFRSTLFTFLTSAFWHGTRPGYYLTFATGALYQTCGKIYRRNFRPIFLREDGVTPLPSKKIYDLVGIYAIKLAFGYMVQPFIILDLKPSLMVWGSVYFYVHIIVAFSFFLFRGPYAKQVTEFFKSKQPKEIFIRKQKKLEKDISASSPNLGGILKAKIEHEKGKTAEEEEMNLGIPPIELEKWDNAKEDWEDFCKDYKEWRNKNGLEIEEENLSKAFERFKQEFSNAASGSGERVRKMSFSGYSPKPISKKEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. : : :: :: : : :: :.. : . :* .:: : . : : : * : *: :: . *: *::: :::*:: . :*. : .::* :::.:** *. .: * :: : : * :: :: : : : : . ::.**: * :.: .*:* . . : : : : .: . * : . : . ** .* **: *: : . : ** ** *** :** : * :: .. : : . : . : :* : :: .. :: . .: . : * . : : :::: ", "identical_positions": 37, "similar_positions": 130, "identity": "5.93%" }, { "cls_id": "homologset.agr.HGNC:32312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX46-1", "uniprot_id": "D3ZX46_RAT", "id": "D3ZX46-1", "name": "ubiquitinyl hydrolase 1", "aln": "-------MDDTEH-----ELQRVIRRHYREKRELQAHIQTLKASVPKNDKGRRKQLLSDIARLEAEMEQRHEQELEKFGENPE-SGVDSVTADLKKMN---------LENM--------PPRPAKSQKRRDRR----ANLERRRQE-RMPAAQ-AEQLAAYRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQLVFS---------VTIESLRYRTAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHKASWGGQLELRALSHVLQTPIEVVQAN-SPIIVIGEEYTRKPLTLVYLHYACDFGEHYNSVKPIEVPGAVGGMAPRLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IE21-1", "uniprot_id": "OTU6A_MOUSE", "id": "Q6IE21-1", "name": "OTU domain-containing protein 6A", "aln": "-------MSDTEQ-----ELQRVIRRHYREKRELQAHIQTLKASVPKNDKGRRKQMLADISRLEAEMEQRHKQELEKFGENPD-SSVDSVTADLEKMN---------LENM--------PPRPPKAQKRRDRR----AHQERRHQE-RMPAAQ-AEQLAANRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQLVFS---------VTIESLRYRTAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHNASWGGQLELRALSHVLQTPIEVVQAN-SPTIVIGEEYTRKPVTLVYLHYACDFGEHYNSVKPIEVAGAFGGMAPRLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L8S5-1", "uniprot_id": "OTU6A_HUMAN", "id": "Q7L8S5-1", "name": "OTU domain-containing protein 6A", "aln": "-------MDDPKS-----EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQD--D-SSIESVVEDLAKMN---------LENR--------PPRSSKAHRKRERM----ESEERERQESIFQAEM-SEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFS---------VSVEMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQAD-SPTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAG-AAGGVLPRLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV00-1", "uniprot_id": "OTU6B_DANRE", "id": "Q7ZV00-1", "name": "Deubiquitinase OTUD6B", "aln": "-------MEEVET-----AEEQLAKQHRKEKKDLQAKIQSMKNAVPKNDKKRRKQLTEDIAKLEAELSQKHENELKLQNT----SSVEEVSDALDSMS---------VANHEEQSDPSKQSRTSKAQKRRDKK----AALEKEREM-RIAEAE-VENLSGSRHQEGLKLREKLVERHLQIKEISSDGHCMYRAVEHQLTERGLA------LGLKELRDQTAQYMRSHADDFMPFLTNPNTGDMYTAEEFEKYCSDVADTAAWGGQLELKALSQVLQLPIEVIQAD-SPCITIGEEYDKPKITLIYMRHAYGLGEHYNSVEPLKDLANEEEG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUN9-1", "uniprot_id": "Q9VUN9_DROME", "id": "Q9VUN9-1", "name": "ubiquitinyl hydrolase 1", "aln": "MCDGDVAIAELESRLDEVSLEDIGARHRRERKDLQAKLQAMKKNAPKNNKNKRKEFLEEMARLEGELEQRHKAELKAAEAMEAPVLVEPVVKEPAEKPETEVTDDDGIEEKEEQLAP--NQRVSKAQKRRDKK----AKEARAREAEIKTELQNAANQPTPKLIELQQITAKLSQRQLSLHNIPSDGDCLYQSIRHQLIVNALPG-----HSVQELREETANYVRAHKDSLISYMIHPETGDILNDQQFEQYCHDIAKTHAWGGHIELKAISSLLRVPIEVIQAEGAPTLLGQEEFGGSPLIICYHRHIYQLGAHYNSTVPAA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38747-1", "uniprot_id": "OTU2_YEAST", "id": "P38747-1", "name": "OTU domain-containing protein 2", "aln": "-------MTGMESGENLENMEDILARHRKENKDLQNKITGMKKQATKS---KRKEVNSKCLDLQDKLKTKQENEIRDWKIANN-EVFDAEQEDEVTPEKLLEQLSISRDEKEQQNVPVQQQQQGQTKKRRNRQKERLAKRDAAIAKMKEEAALEASKQPDLKKMEQESIDQLCELKKLKQFDIQPDGHCLFASILDQLKLRHDPKKLDQDMDVMKLRWLSCNYVQEHRDDFIPYLFDEET---MKMKDIDEYTKEMEHTAQWGGEIEILALSHVFDCPISILMSG-RPIQVYNECGKNPELKLVYYKHSYALGEHYNSLHDS--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : :* :*.::** :: :* ..*. :**:. . :: :: ::. *:. .: : : :::::*:: : . : * .: : *. * .**.*:: :: .** : ** :. *:: * *.::.:: . :: .:: * :: . ***.:*: *:* :: **.:: : * * : : * :: :* **** ", "identical_positions": 40, "similar_positions": 88, "identity": "11.9%" }, { "cls_id": "homologset.agr.HGNC:32315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5JR98-1", "uniprot_id": "DYLT4_HUMAN", "id": "Q5JR98-1", "name": "Dynein light chain Tctex-type 4", "aln": "----------------MASRPLPPGRQEEENAKDSGRKPSPVRPRGCLPSIDE---ARPAGPGPAPASRRGSMLG------------LAASFSRRNSLVGPGAGPGGQRPSLGPVPPLGSRVSFSGLPLAPARWVAPSYRTEPVPGE--RWEAARAQRALEAALAAGLHDACYS-----------------------------------SDEAARLVRELCEQVHVRLRELS--------------------------------PPRYKLVCSVVLGPRAGQGVHVVSRALWDVARD---GLASVSYTNTSLFAVATVHGLYCE--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CDY7-1", "uniprot_id": "DYLT4_MOUSE", "id": "Q8CDY7-1", "name": "Dynein light chain Tctex-type 4", "aln": "----------------MACRTLPSRRQEEETTKDLALKLPPGKPGGHLPSIDE---TRPIGPG--PASRRGSLPG------------LHPSFSRRNSLAGPLVGPGGRRPSLGPVPPLGSRVSFSGLPLMLPRRMAPSYRLEPAPGE--HWEAAGAQRALEAALTTQLNGVCYC-----------------------------------GSEAGKLVQALCEQIHTRVRELN--------------------------------LPRYKLVCNVVLGPREGQGVHVVSRALWDAVHD---GLASATFTNPSLFAVATVHAVYWE--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4LEE2-1", "uniprot_id": "A0A0B4LEE2_DROME", "id": "A0A0B4LEE2-1", "name": "Tctex1 domain-containing protein 2", "aln": "----------------MTSWTTMKTRITASVR---------------------------------TTNRMNALLS------------ESMLSRRRAAQNPEGEATGGEAGEPRKEKPKNDWKFFH-----------TNFNMERAQK--------IIEDCIEERLLWDRFSRNYD-----------------------------------SWRALQLAEGLAAEIRDRVKKLN--------------------------------HRRHRIVCLLSIVEKQNQGVYQRMCHLMDEKRD---NFTQLVFERPTYFMIVVLYLVYKD--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3Z860-1", "uniprot_id": "D3Z860_RAT", "id": "D3Z860-1", "name": "", "aln": "MENPGLVVRGQAAPFSTALRSLINNPRYSDICFVVGQERQEVFAHRCLLACRCNFFQRLLGPGIPSPVVLSTVPAEAFLAVLEFLYTNSVKLHRYSVLEVLTAAVEYGLEELRELCLEFVVKVLDVELVCEALQVAVTFGLEPLQKRCIAFIETHSQEALRTRGFLELSATALLPVLRSDKLCVDEAELIQAARSWARVGAVSGVWGLDDDAEAAQAAGFCKRARGTGSRLSSIGGVGATRGRGGSSSGSRAEIGSARPSGAKRPGRTEPTGASHSGADASNQTYIHSATWGRGARTEGQGLPACMVTRFPLQVEQIVEAWKCHALRRGDAARSALCRRRRGTLPRDHHRFLDLRF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .. .:: . * . . : .: * : .:. . . :. . : .*. * . . .: .: : .:. . . : . ", "identical_positions": 4, "similar_positions": 40, "identity": "1.12%" }, { "cls_id": "homologset.agr.HGNC:3232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88281-1", "uniprot_id": "MEGF6_RAT", "id": "O88281-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MPVRAEARAAWR--VVALALLLLPAMPAAS--PPLTP-RPLQPSMPHVCAEQKLTLVGHRQPCVQAFSRIVPVWRRTGCAQQAWCIGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDV-----------------------------------DECASANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDECRAHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCAEGNGGCMHICQELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCAN-SPCCQQACANTPGGYECSCFAGYRLNTDGCGCEDVDECASGHGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTSLEESVVDLDGRLPFVR--PLPHIAVLRDELPRLFQDDYGAEEEAAAAELRGEHTLTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGQDGCDCPEGWTGIICNETCPPDTFGKNCSSPCTCQNGGTCDPVLGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNPKDGSCSCKAGFQGERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGASCNPETGTCLCLPGFVGSRCQDTCSAGWYGTGCQIRCACANDGHCDPTTGRCSCAPGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPRCEQSCRQGYYGPSCEQKCRCEHGAACDHVSGACTCPAGWRGSFCEHACPAGFFGLDCDSACNCSAGAPCDAVTGSCICPAGRWGPRCAQSCPPLTFGLNCSQICTCFNGASCDSVTGQCHCAPGWMGPTCLQACPPGLYGKNCQHSCLCRNGGRCDPILGQCTCPEGWTGLACENECLPGHYAAGCQLNCSCLHGGICDRLTGHCLCPAGWTGDKCQSSCVSGTFGVHCEEHCACRKGASCHHVTGACFCPPGWRGPHCEQACPRGWFGEACAQRCLCPTNASCHHVTGECRCPPGFTGLSCEQACQPGTFGKDCEHLCQCPGETWACDPASGVCTCAAGYHGTGCLQRCPSGRYGPGCEHICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCACRQGAACDPVSGACICSPGKTGVRCEHGCPQDRFGKGCELKCACRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECFCQNNGSCEPTTGACLCGPGFYGQACEHSCPSGFHGPGCQRVCECQQGAPCDPVSGQCLCPAGFHGQFCEKGCESGSFGDGCLQQCNCHTGVPCDPISGLCLCPPGRTGAACDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYMGPTCR--------EVPTQISSSR---PAPQHPSSR---AMKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80V70-1", "uniprot_id": "MEGF6_MOUSE", "id": "Q80V70-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MPVGVEARASWR--VVALTLLLLPAVPAAS--QPLPP-RPLQPSMPHVCAEQKLTLVGHRQPCVQAFSRVVPVWR-SGCGQQAWCVGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDV-----------------------------------DECANANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDECRSHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCADGNGGCMHTCQELRGLAHCGCHPGYQLAADRKACEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCAN-SPCCQQVCANTPGGYECSCFAGYRLNTDGCGCEDVDECASGHSGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTPLEESVVDLDGQLPFVR--PLPHIAVLGDELPQLFQDDYGAEEEAVA-ELRGEHTLTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGLDGCDCPEGWTGIICNETCPPDTFGKNCSSPCICQNGGTCDPVSGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNSKDGSCSCKAGFQGERCEAECEPGSFGPGCRNRCTCRPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGASCDPETGTCLCLPGFVGSRCQDACPAGWFGTGCQMRCACANDGHCHPATGRCSCAPGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPQCEQWCRQGYFGPGCEQKCRCEHGATCDHVSGACTCPAGWRGSFCEHACPAGFFGLDCGSACNCSAGAPCDAVTGSCICPAGRWGPHCAQTCPPLTFGLNCSQICTCFNGASCDPVLGQCHCAPGWMGPTCLQACPAGLYGKNCQHSCLCRNGGSCDPILGQCTCPEGWTGLACENECLPGHHGAGCRLNCSCLNGGTCDRLTGHCRCPAGWTGDKCQSPCVSGMFGVHCEEHCACRKGATCHHVTGACLCPPGWRGSHCEQACPRGWFGEACAQRCHCPPGASCHHVSGECHCPPGFTGPGCEQACQPGTFGKDCEHPCQCPGETWACHPASGACVCAAGYHGTDCQQRCPSGRYGPGCEQICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCTCGQGAACDPVSGTCICPPGKTGGHCERGCPQDRFGKGCEHKCACRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECSCQNNGSCEPTSGACLCGPGFYGQACEDTCPAGFHGSGCQRVCECQQGAPCDPVSGRCLCPAGFRGQFCERGCKPGFFGDGCLQQCNSPTGVPCDPISGLCLCPPGRAGTTCDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYTGPTCR--------EVPTQLSSIR---PAPQHSSSK---AMKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75095-1", "uniprot_id": "MEGF6_HUMAN", "id": "O75095-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MSFLEEARAAGRAVVLALVLLLLPAVPVGASVPPRPL-LPLQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWK-AGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLS-------------------------------------AECS-ASLCFHGGRCVPGSAQPCHCPPGFQGP---RCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVR--PLPHIAVLQDELPQLFQDDDVGADEEEA-ELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLR-------------------------------------------GWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TH19-1", "uniprot_id": "A0AB32TH19_DANRE", "id": "A0AB32TH19-1", "name": "", "aln": "---------------MDLHVLLLLLFLLTKIRPSCCL-RALHPFMPNVCSEPERVIRAEKQPCVQAFIQMVKVWR-QGCTGHAWCMDFERRTTYYIGYKQVYRQDFKMAYKCCPGWSQNNSKMGCLY----------------------------------------------------------------------------HIDECQVHNGGCQHRCVNTRGSYYCECNPGFRLHVDGRTCIAVLSCSVNNGGCEHECVQLSPVHFQCRCRRGYQLTADGKRCRLRNPCVEKNGGCVHLCRSDGGRVVCSCHQGFMLAVDQKSCEDVNECETGLAACAHSCRNTPGSFSCICNPGYELGSDGRKCYRIEMEIVNTCDSDNGGCSHRCQHGVLGPVCSCNHGYQLAEDLKTCLDLEECEEGTSCCEQDCTNYPGGYECYCRAGYRLNADGCGCDDVDECASDRGGCEHTCQNTAGSYHCFCRFGYRLGEDRHSCISLQRSVEELPGPVVVER--PLLHLALLQDYPQPLER--YHDYEEDSFGELRAESTFAEKFVCLNGTFGHDCSLTCDDCSNGGYCNAEGDACDCPDGWTGILCNQTCPEGTFGKNCSFTCKCRNGGTCDPISGKCRCPPGVNGDLCQDGCPKGMYGKHCNKKCNCANNGRCHRTYGACLCDPGLYGRFCHLPCPKWSYGSGCSSECQCVQQNTLECHRRHGTCVCKPGYQGKTCNRECDSGFYGPGCRLKCQCPAGVSCHPMSGQCQRQCPAGLHGEHCDRECPMGQFGVGCTQFCDCKGAPCNSVTGKCHCPAGQTGQHCEKECEEGRWGLGCAESCPSCDNGGVCDRQNGTCVCSPGFMGNLCQNVCPDGHFGLSCLLRCSCQNEGKCHHVTGLCVCKDGWMGPNCAKACVAGRWGPNCANQCDCRSSVGSCDPVIGLCHCEAGYMGPRCDQKCPQGFFGQSCQHRCQCENGAVCEHVSGACTCLAGWTGTYCEKPCPEGFHGLECQQKCQCLNGGRCHPVTGGCQCPSGWVGPVCNATCEAGTFGPACSQTCRCHNNGTCDPADGRCECGAGWTGSSCEQECSAGLYGVGCNQHCLCQNGGSCDRISGHCTCVSGWTGVACELECAAGHFGMDCQHKCECVNGGVCDRHSGRCLCPAGWTGTHCETACTQGFYGPGCKERCRCDHNAACHHITGTCLCPAGWRGTHCEKVCLPGSYGKRCAHRCQCPHGTSCNHVTGQCGCPAGLTGSGCERMCQSGTFGVNCNQVCQCSELNQLCHPVTGVCYCAPGYYGSKCETECEAGRYGPNCEQECQCLNNGVCKSSTGTCSCPPGFIGPNCNITCPLGRYGQDCAGVSLCGEGARSDPLTGRCVCRAGQRGRDCGKGCAEGWFGENCDQRCNCSNGGVCDALTGHCSCTLGWTGDTCEEVCPRGRYGSDCSEVCDCKNNSTCDRVTGVCLCSPGFYGHLCQHACPVGFHGHRCQLLCDCGANAPCDPETGRCLCPAGYQGLRCERECELGTFGADCVHRCDCDGDTPCDPINGRCLCAPGKTGSRCDIGCGVNRFGPDCSQRCECLNGGQCDPRNGRCTCLNGWIGPSCQQA------EWPSLNVRRCTHWMTLVYKALLALVPS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B4A3-1", "uniprot_id": "A0A8M3B4A3_DANRE", "id": "A0A8M3B4A3-1", "name": "", "aln": "--------------MKNVDLLLSLIILVDGINAVSRLGKDLKPHMPNVCAEKEVKLVAQMQPCVQAFTRMVKAWK-QGCQGQSWCVGYERRTAYYTAYRQVYRQEQQTVYKCCPGWSQLNGEAGCLYPVCRSGVCFNGGQCKEGSAQLCVCPAGFSGPSCQYDVNECEETNGGCEALCCNTIGSFYCKCPAGQELKEDGKTCQDIDECQVHNGGCQHTCVNTRGSYHCQCNAGSRLHVDGRTCIAVQSCGVGNGGCEHFCVQQTAGHVQCRCRPDYRLDADGKHCTLVNPCAEQNGGCSQMCHRDGAQARCECHPGYQLAEDGKTCEDIDECALGQTDCAHGCRNTRGSFMCVCSAAYELGVDGKQCYRIEMEIVNSCDHDNGGCSHHCEHSTAGPLCSCNEGYQLDHDHKTCVDINECVDGSSCCEHDCTNYPGGYECYCTAGYRLNTDGCSCDDIDECLAVNGGCDHACLNSAGSFQCSCRRGYRLDEDRRSCILMEESVEALSSGQTVNKPGPGPQLTILQDFDQILEK--YEDYEDD-TGELRAESTLAEKFICLNDSFGVDCSLSCEDCVNGGVCNKHRNACDCPDGWTGVVCNETCPEGWFGRNCSLLCKCKNGGVCDPVSGSCRCPPGVSGELCQDGCPKGLYGKFCNKRCNCANNGRCHRTYGACLCDPGLYGRFCHLPCPKWMFGPGCSEECQCVQQNTIECHRHHGDCICKPGYRGHTCKDECESGFFGSACENKCSCPPGVTCDHVTGACQPKCPAGKTGDKCDQDCVEGRFGIGCSQSCDCSGAPCDKVTGQCTCPAGTFGKRCEKECPEGRWGLGCQEWCPVCENGGRCDRRNGTCVCSPGFIGRLCQNSCPAGRFGVGCQLRCVCDLGVRCNPVSGRCSCPPGWTGHNCRKVCDAGRWGLDCESVCDCRNADGVCDAQTGRCHCEAGFTGARCDQKCPAGSFGPGCKHRCQCENQASCDHVGGACTCKTGWTGTFCEKPCPQGFYGLDCQQKCVCLNGGLCDHVSGQCFCKAGWIGTRCNQTCPAGWFGVSCSQTCVCHNNSSCDAVSGQCECGAGWTGDTCSQRCPAGVFGDGCVHRCLCQNGASCDPESGHCFCPSGWTGAACQLECPAGRFGSDCQDRCECVNGAQCDGQTGRCVCPPGWTGERCENECERGWFGVGCEDRCQCDHGAVCHHVSGQCLCPAGWRGRRCEKACLPGSFGQDCVQRCSCPSGSSCHHVTGHCGCAPGFTGDGCEHSCLPGTFGQDCNQVCQCSERNQLCHPVTGVCYCAPGFTGLKCEQTCPQGLYGSGCEHQCECLNGGVCLSDSGSCQCPAGFIGAQCNQTCPAGRYGLDCAHVSACGTGVRNDPATGRCTAHQ---------VCPPGWFGSGCSQRCDCSNRGVCDGVSGNCSCALGWTGKHCDKECPDGSFGPDCSLQCSCQNNSTCDRVTGSCHCRPGYYGHLCEHACPAGLFGSGCQQQCDCMNGASCHPDTGQCVCPAGVHGPRCQHVCAQGRFGVNCSQSCDCADGASCDPVSGRCVCPSGKTGVRCDSDCSVNRFGPDCSLLCECENGAQCDSRNGRCFCLSGWIGFTCSQS------APPELNSRRSE-------EDQLQLNTS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :** . *:* **:**:* : : .. ******: : * .*: ** ::**:. ****.** .*:*** : : . :** ** * .: *** .:***: ******* **** *** *:*:.* ***.*.***:*: ** :.****:* *** : : :*:** ::* **::* .**.: **.* : *: . . * ** *: ** * *:***::** * : ***.* ** *** *:* ..**** **::**********:*: .****** *.* **:*:* .**:* * :**:*:::* : :.**:: *:* ****** * *****.:***.*:*:*** : ..**:* * * ***::* *. **** ***:.* ::..: * . . : * ::::* * * : :: ***.* *::***:**: :** ****:*:** *** * :.****:****::**:*** . **:*** * *:***.**.: * *******.* *:****** ***.*.*:*:***.***** *****************.** * :*.***.:* * * :* .*. :.* * **.*::*. *: **: * :*..* * * **:*. ::* * :**.* *:.*.::* * **:.*: *.* ****. ***:* **.* *: * :* ******** * ** *::.. *: ..*:*:* ***:* **: *. * :* .* ** * :*. .:* * * ** * .* :.* :*:** :* *:* . * **. * * ****: *.:*:* * * :* .*:::*:*:: * *:**.***** :** *::**:.** **.**:* . * * *. *. *.* * * :* *. * :* . :* *** * *.*..:**.. *:*.*..** * :* * *..*::* .* : ***:**. ** *:* * .**:* **: ** . .*: *::*. ** :*:* **.**** :*:. * * :*: *.:** ** .::*:**:* * *..*:** .**: * .*:** :* : ***. . *.*.:*.* **.*: * * * * **..**: * ***.* * . :*:* **.**:*.:*. :** **:* .*: *. * *. ** :* * . *. . ** .*. * * * *:*.. .* *** *** * *: ** * :*. * * *:**.:*: .:* * * **:**: *:..** *:.* ** * * .*.*.* :*:*:**** :* *:: * * ** .* : *:. ...***:.* *:*..*::* *: .* .:***.*: *:* .*.:**. .*:* *:..: * :* * . ", "identical_positions": 653, "similar_positions": 385, "identity": "40.04%" }, { "cls_id": "homologset.agr.HGNC:32322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N7T827-1", "uniprot_id": "A0A8N7T827_DANRE", "id": "A0A8N7T827-1", "name": "", "aln": "-MSFAMVRPTPG--HYLCSEINMHSEDDDNGSEG-SGSEDKSFRTSSHGYGSFKLGVRKK-------RYSCRPLAIPTELCTPITEVRQRNTANARERERTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGEECGDGQPCLR--SSGSLFHHHHNVSKSSTPSPDS-------ENSQPRQICTFCLSNQRRLNKDRERKTVLRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NCA2-1", "uniprot_id": "A0A8M1NCA2_DANRE", "id": "A0A8M1NCA2-1", "name": "", "aln": "MMSFAMVRPAPS--RYVYSDISMMSEDDENGSES-SGSDDRSFHLDTSGY-DLKVGRKRKSSVGGGGRLIGVTPTIPTGTIGHVPEIRQRNAANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGEACGDGQPCHSGGPSTSNYYHHH-----GSPSRDS-------ENSQPKQICTFCLSNQRKMSKDRERKSALRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7RTU7-1", "uniprot_id": "SCX_HUMAN", "id": "Q7RTU7-1", "name": "Basic helix-loop-helix transcription factor scleraxis", "aln": "-MSFATLRPAPP-GRYLYPEVSPLSEDEDRGSDS-SGSDEKPCRVHAARC-GLQGARRRAG-----GRRAGG--GGPG--GRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHS---GPAFFHAARAGSPPPPPPPPP--ARDG-ENTQPKQICTFCLSNQRKLSKDRDRKTAIRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64124-1", "uniprot_id": "SCX_MOUSE", "id": "Q64124-1", "name": "Basic helix-loop-helix transcription factor scleraxis", "aln": "-MSFAMLRSAPPPGRYLYPEVSPLSEDEDRGSES-SGSDEKPCRVHAARC-GLQGARRRAG-----GRRAAG--SGPGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGEACGDGQPCHS---GPAFFHSGRAGSPLPPPPPPPPLARDGGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q59E67-1", "uniprot_id": "Q59E67_DROME", "id": "Q59E67-1", "name": "BHLH domain-containing protein", "aln": "-MAVSSSSSSFS--NYLMAVFAQDSNSSGSASGSGAAADSEDSQIGQEAN---PGGQENQG-------------------NHRRRPPRQK--INARERYRTFNVNSAYEALRNLIPTEPMNRKLSKIEIIRLASSYITHLSSTLETGTEC---QPCLL--------HKYE---------SEG--------ITRRISICTFCLKTK---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.: .: .*: . . *:.. .* . :.::.. : . .. **: ***** ** .**:*: ***.****** :******* :*******:**...* .* * *** : . :: .******..: ", "identical_positions": 53, "similar_positions": 44, "identity": "24.09%" }, { "cls_id": "homologset.agr.HGNC:32324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLL3-1", "uniprot_id": "LRC55_RAT", "id": "Q4KLL3-1", "name": "Leucine-rich repeat-containing protein 55", "aln": "MGDTWAQLPWPGPPHSALLLVFFLLAAGVMHSDAGASCPVLCTCRNQVVDCSNQRLFSVPPDLPMDTRNLSLAHNRIAAVPPGYLTCYMELRVLDLRNNSLMELPPGLFLHAKRLAHLDLSYNNLSHVPADMFREAHGLVHIDLSHNPWLRRVHPQAFQGLVHLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKANEEEEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UY51-1", "uniprot_id": "LRC55_MOUSE", "id": "Q3UY51-1", "name": "Leucine-rich repeat-containing protein 55", "aln": "MGDTWAQLPWPGPPHSALLLVFFLLAAGVMHSDAGTSCPVLCTCRNQVVDCSNQRLFSVPPDLPMDTRNLSLAHNRIAAVPPGYLTCYMELRVLDLRNNSLMELPPGLFLHAKRLAHLDLSYNNLSHVPADMFREAHGLVHIDLSHNPWLRRVHPQAFQGLVHLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKANEEEEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSA7-1", "uniprot_id": "LRC55_HUMAN", "id": "Q6ZSA7-1", "name": "Leucine-rich repeat-containing protein 55", "aln": "MGDTWAQLPWPGPPHPAMLLISLLLAAGLMHSDAGTSCPVLCTCRNQVVDCSSQRLFSVPPDLPMDTRNLSLAHNRITAVPPGYLTCYMELQVLDLHNNSLMELPRGLFLHAKRLAHLDLSYNNFSHVPADMFQEAHGLVHIDLSHNPWLRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKASEEEEI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************.*:**: :*****:******:****************.************************:*************:****:******** ******************:********:***************************::*********************************************************************************************************************************.*****", "identical_positions": 281, "similar_positions": 15, "identity": "94.3%" }, { "cls_id": "homologset.agr.HGNC:32325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCQ6-1", "uniprot_id": "D3ZCQ6_RAT", "id": "D3ZCQ6-1", "name": "Protein Flattop", "aln": "MATNYSANQYERAYLPRYLQNWSPAKPTKEKIATHEGYTQIIANDRGHLLPSVPRSKASPWGSYIGTWQMPLKIPPAKANLTARTTAAADSLTEW-----------------------------------IHKNPDLLNACNGLRPEIIGKPRDL---------NSQKKQ-KKSVTKTVQQALNPTIIPSSPVIQGDNPDEPQSSHPSAGHTPG-PQTPLNSPKNPPPSPS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P8X9-1", "uniprot_id": "FLTOP_MOUSE", "id": "Q6P8X9-1", "name": "Protein Flattop", "aln": "MATNYSANQYEKAYLPTYLQNWSPARPTKEKIAAHEGYTQIIANDRGHLLPSVPRSKASPWGSFMGTWQMPLKIPPAKVTLTARTTTAADNLTKW-----------------------------------IHKNPDLLNACNGLRPEISGKPFDP---------DSQTKQ-KKSVTKTVQQAPNPTIIPSSPVIQGDNPDEPQSSHPSAGHTPG-PQTPVNSPNNPPPSPCKSTK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTH2-1", "uniprot_id": "FLTOP_HUMAN", "id": "Q5VTH2-1", "name": "Protein Flattop", "aln": "MATNYSANQYEKAFSSKYLQNWSPTKPTKESISSHEGYTQIIANDRGHLLPSVPRSKANPWGSFMGTWQMPLKIPPARVTLTSRTTAGAASLTKW-----------------------------------IQKNPDLLKASNGLCPEILGKPHDP---------DSQKKLRKKSITKTVQQARSPTIIPSSPAANLNSPDELQSSHPSAGHTPG-PQRPAKS-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P4F6-1", "uniprot_id": "FLTOP_DANRE", "id": "Q0P4F6-1", "name": "Protein Flattop", "aln": "MSTSYSANQYESAFKSQKLQNWTIPKQFKERPSAAEGYTTFIATDRGHLLPGVRTKHRSAWPAFQGTWDLPRRIPPVSMNPTARSQVGQDRLMTWGQMKI--------------------------TTKQAHKGPGDSQAMNRNSHDVENINVDQPAEQSKISIDPDENQPEKPKSQHIQDQSRPASQQAQPIPENLNINQSRPASQRSQKAPSRPATQQNQAEFRPPTHNSRPASQEK--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4I5-1", "uniprot_id": "FLTOP_DROME", "id": "Q9W4I5-1", "name": "Protein Flattop homolog", "aln": "MALHFSAQQFEGRFQSKRLNNWEYPRFSPPRPRGLQKNAKVVAANNGHLLPEVIK-EGNSFGQYRGTYELPRRITRAFCAHYDACLSGRYKFVDFPRDLCNCQRENRRALACDQRLTLGHKDDPYWMRERCQTKCEGLQKLRALSERSARCNRAKCDVVSEKTVKMTPKAIKTTGVATEKRRRKRTITAFSKGRTALHPNELTKPIPSSEKPAATVATPKDKPKDKPKDKEAGKKDKTKDKGKEKERKAAKGH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :**:*:* : . *:** .: : : .:* :.***** * . ..: : **:::* :*. . . : : :. : . . : :.. : : . :: . : :... .. ", "identical_positions": 19, "similar_positions": 51, "identity": "7.51%" }, { "cls_id": "homologset.agr.HGNC:32326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB51-1", "uniprot_id": "TUTLB_RAT", "id": "D3ZB51-1", "name": "Protein turtle homolog B", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVISTRGLVAQVAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQPPPYVVEWFK----FGVPIPIFIKFGYYPPHVDPEYAGRAS------LHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLSASGKYQVSDG--SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDP---FPVITWR-KVGKPSRSKHN---ALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGG--YEQTFSVWM----KRAQFGPHDWLSLSVPL-GPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVT-------------------PPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVGERWEMLD-DAIPGTDGEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPL-----------------------------SSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEAT------TPIELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDP-LVPTSVAALKP-QLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGG-RLQATGQAR-PPAPRPFQHGQYYG--YLSSSSPGEVEPPPFYMPEVGSPLSSVMSS-PPLHTEGPFGHPTIPEENGE------NASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFP--HQLHPCDVAESLQPKPCLPRGLPPAPLQVPAAYPGMLSLEAPKGWVGKSPGRGPIPAPP------ATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFG---LDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQA---EMSEITLQPPAAVSFSRK---STPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDNLDVFGQTPSPRRMGEEPLRPE-PP----------------------------------------------------------TTLPTSG-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZ19-1", "uniprot_id": "TUTLB_MOUSE", "id": "E9PZ19-1", "name": "Protein turtle homolog B", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVISTRGLVAQGAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQPPPYVVEWFK----FGVPIPIFIKFGYYPPHVDPEYAGRAS------LHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASAKYQVSDG--SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDP---FPVITWR-KVGKPSRSKHN---ALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGG--YEQTFSVWM----KRAQFGPHDWLSLSVPP-GPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVT-------------------PPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVGERWEMLD-DAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPL-----------------------------SSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEAT------TPIELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDP-LVPTSVAALKP-QLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGG-RLQATGQAR-PPAPRPFQHGQYYG--YLSSSSPGEVEPPPFYMPEVGSPLSSVMSS-PPLHTEGPFGHPTIPEENGE------NASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFP--HQLHPCDVAESLQPKACLPRGLPPAPLQVPAAYPGMLSLEAPKGWVGKSPGRGPIPAPP------ATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFG---LDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQA---EMSEITLQPPAAVSFSRK---STPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDTLDVFGQTPSPRRMGEEPLRPE-PP----------------------------------------------------------TTLPTSG-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPX0-1", "uniprot_id": "TUTLB_HUMAN", "id": "Q9UPX0-1", "name": "Protein turtle homolog B", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATFIASVIGTRGLAAEGAHGLREEPEFVTARAGESVVLRCDVIHPVTGQPPPYVVEWFK----FGVPIPIFIKFGYYPPHVDPEYAGRAS------LHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVSDG--SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDP---FPVITWR-KVGKPSRSKHS---ALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVQVSMTTANVSWEPGYDGG--YEQTFSVWM----KRAQFGPHDWLSLPVPP-GPSWLLVDTLEPETAYQFSVLAQNKLGTSAFSEVVTVNTLAFPITTPEPLVLVT-------------------PPRCLIANRTQQGVLLSWLPPANHSFPIDRYIMEFRVAERWELLD-DGIPGTEGEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTEDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPL-----------------------------SSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSKKYSVAKAEAEAEAT------TPIELISRGPDGRFVMDPAEMEPSLKSRRIEGFPFAEETDMYPEFRQSDEENEDP-LVPTSVAALKS-QLTPLSSSQESYLPPPAYSPRFQPRGLEGPGGLEG-RLQATGQAR-PPAPRPFHHGQYYG--YLSSSSPGEVEPPPFYVPEVGSPLSSVMSS-PPLPTEGPFGHPTIPEENGE------NASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFP--HQLPPCDVPESLQPKAGLPRGLPPTSLQVPAAYPGILSLEAPKGWAGKSPGRGPVPAPP------AAKWQDRPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGAHGGPSTFG---LDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQA---EMSEITLQPPAAVSFSRK---STP-STGSPSQSSRSGSPSYRPAMGFTTLATGYPSPPPGPAPAGPGDSLDVFGQTPSPRRTGEELLRPETPP----------------------------------------------------------PTLPTSGKLQRDRPAPATSPPERALSKL----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9NYK6-1", "uniprot_id": "A0A8M9NYK6_DANRE", "id": "A0A8M9NYK6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFK----FGVPIPFFINFRFYPPHVDPEYAGRAS------LHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSDG--SLTVQAITREDRGAYSCRAHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPE--IPTIQWR-KVGKPSRSKHN---LLPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLFVIGTSPHAPTNVHVSASTSSANVSWEPGYDGG--FEQTFSVWYGPVKVKNDVGTHDWLSIPVPG-SQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLT-------------------PPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLD-DLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTDPFPPTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPPPLTPLPGIEPYWEEPDRSSYRPPSTSPQLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSK--HEAEVT------TPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRP-QISPVSSSQESYMQPPAYSPRFQ-RPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYG--YIGSGAEVEL-HPPFYMPDV-SPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVS-TTSQLPS-SSAFLQLEAPRTHLSRSPGRFPPQGPS------AKHIT---MQQAQTLGQLRHTAHGMGVPVLPYSGATT--RMGSPSTLHSESSDGWRSEAQP--WMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHP-ASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSP----PAESSDAFGQMPSQRRTDEEMLPSEPSP---------------GEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TAW7-1", "uniprot_id": "A0AB32TAW7_DANRE", "id": "A0AB32TAW7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTSRAGETVILGCDVVHPLNGQ--PYVVEWFK----FGVPIPFFINFRFYPPHVDPEYAGRAS------LHGKSSLRIERVRSEDQGWYECKVLMLEQQYHTFHNGSWVHLTVNAPPTFTDTPPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGNPVQDSTKYKVSDG--SLTLVSISREDRGAYTCRAYSEQGEAVHTTRLLVQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQVKPEDAGKYTCSPSNSLGRPPSASAYLTVHYPARVINMPPVIYVAIGLPGYIRCPVDANPPVTSVKWKKDGLPLRIEKYPGWSQMEDGSIRVSEVTEDSLGTYTCVPYNSLGTMGPSPPAPLVLKDPPKFLVVPGGEYRQEAGRELVIPCEAEGDP---FPNITWRKKVGKPSRSKHN---VLPRGSLQFKSLSKEDHGEWECVASNVATSITASTHLLVIGTSPHAPAKVHVTVSTTSANVSWDSSYDGG--FEQTFSVWYGHVVKREQLGPHDWLSMPVPS-GQHWLLVQGLEPETAYQFSVLAQNKLGTGPFSEVVTVNTLVFPISTPEPLVLLT-------------------PPRCLTANRTQQGVLLTWIPPANHTSPIDHYIMDFRLGERWDVLD-DAIPAGETEILARDLIQEAWYEFRVMAVMEDLVSEPSNVVGVSSTDYFPPPEVPDEGLARPVVAGIVATICFLAAAILFSTLAACFVNKQRRRKLKRRRDPPLSITHCRKSVETPS-----------------------------SSGKISPESIRSIGPPSESSE--DGLRAKKFPQSPAKEELSLYKKTKRAIISKKYSVSK--HEAEAT------TPIELISRGPDGRFVMDPTDMETPVKARRIEGFPFVEESDLYPEFRQSDEENDDPGPMPPVMATLRPHQISPISSSQESYLQPPAYSPRFQ-RPMEGMTIMETSRLQATGQIRGAPHFRAFTHGQFYS--YLGSPGEPEP-PPPFYMPDT-SPLSSVMSS-PPYHLEGPFGHPTIPEEIGEGEIQHYAVSGYTLPLAH-PSTSRSPDIWQRPDFTFATIEGPHFIFPPPHPLHLHPEPPLPPPLVLPPSALQPSTLQVSP-YPGILQLEAPKSRPGKSPSKVKPQGLP------AKRLP---MQEAQSLGQLRHTSHGMGVPVLPYPDPVS--HMVGPSSFG--SLDTRWYELTP--RLSPRQPRRMEP--SMVVLQPSRLSPLTQSPISSHEGSPEIVVRPRPRPSMIQPPIPPEMSEITLQPPSSASFSRR---SSPSSSPAQGQGSRRASPSYRSHMAFATSAASYPSQSPSP----PVESSNIFGQMPTQRRTEEEILPSEPSPPQLSASGYIHYVAILRKRRGAPSGSAGSERIEALRYQRVKKAKKVGIN-NNNSKARRKTGVPPSQTQQPHTSQVLQPEEALYLRKKK--KKLTRQDPYARFSALLYRRPTREDQKAILASMDTADPDHATLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q967D7-2", "uniprot_id": "TUTL_DROME", "id": "Q967D7-2", "name": "Protein turtle", "aln": "MGVCADLGSHRWCRALSTQHNTEKSKEQQQQSQPLEIPEQRASKCRGDIDRTTTTTIPASKTLTASPAKTAAFTVKTTRRRRSRRRAEGSSICVPIRRGQGSTPTPTIQVLQFVLVSLLALLAKNAQ-AHNIPEDAVHITAILGEGVIFNCHVEFP-NDHPVPYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATLMAVTQLVIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFR------EAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAPAAPRNVKAATQPPDSFFQLMPDEAGPKPGPPRNVSVTEVSNGFLITWQSPLERAHIVKFYTIKYRTDAQWKTLNRGQIRPEETQYLVKNLVGGRTYYFRVLANSEKSYESSDEVK-------FP---VPARVKHKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQEKEFNMVACRITDARNIAANN-------------------------------HHLHNRSTGSISSGQVPLKKYKQTRISSLTAILIAILHWIWPPDRCTNCHSIYSSPNLEDGDEDDGGGGRRRSVSRIQRSLDGRFVLDVEGVSKLGYSQQTLESGNVDVVDGGLFERRNSNVSQKSSSDDGGFLSRRN--FITARASWRRPLVASSSQLSLQSAADSARGFLQGLLKIGAKQSAVPPNSQSYFDEAVSGARYQNVLRPYTSSNNLYGNADRSRPLHINTIS-GSLSQQQQLYTPSRISRIFSSSPQQLQPHHQQLLLSSGGSGAYPTHFSDLSTVYPPNSAERSSHNLSSRYRYYSQELPSLRTIQEETRRQQQQKQHPLEDHFVPLQLPSPPSWRSYYQSQASYRPRTRWYPRHHSRLFSNRQQQHEMLSPLPQLNLNLRNSMNPGGLEASPESRSSSSGFG---SKNTSNHPGSTSEWRLLPPYRAPPSPPKHSGYFGGQQAQGQTPHGSYS-YPRATTPPYTMAHWLEMISRLNAATDSNLPKAPCPVDVG--SVDGHYEFDPATPTPSASSMLREDLNLHIDTHPYHHHTLGPLSGSLLHSHAPYGGGARKQRSLPAHLPRYDNVEVR-------------------------------------------------------LQAMREEFYAYRKRQAMQQMESVC--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .:.*::. . *: **.: *:. .:*: ** *:: *.* .* ..: ***::* * * :*::* : ** *:: * **.* ...:**.: .:*..*******:*::*::: . .:**:*.** ::*** *: ** : : .. *.** :.* * *.*.* : * ::. : : . : :. .* : :: :** * *:* * . :*:. **::::: * . *: ** * * .:.. ::*.*:* ***:* *: : . * *: ** * **:*** :**:*:*:* * :*.:* . ******:*.***:* *.* *:. : * ::* :.:.* * * ** *. : . * :**: . ...*: * *:*.*** ** * * ::::.** * * * *:::.* .: : * * * * *: : *: ..: :. *.: : * :**.* ::**.:* .::: * *:* : **.**** .: .: :: .:.* ..*.** ::* :::* : * :** ::.*. . : :: * . *:*:*.*:.:* ** . :*:*:** * . ::*. : * *** : .....:*.*::* .* ::: :. * :.:* :*. *: . * : : :.::* * **.:* :. ....:: ** :. :.: **:*. * *: .**::*. *. : **:::** ::. : . :.: : :: .* : . . . . : :: : : ** .: * .:. *.*. *****:. :. :: .: * *:..: .:.. . : : : . :* : ..: . :* .. .: * . : : . * . : .: * * . : : *: .. . * * . . ... . . : . . : *.* :* . .: . : * . * : .: .: * . ..* : . . . . : . .. *:* .* * . . . . :. : . : * :. ... . * * : : : * . .* .. :* . :* * . ", "identical_positions": 266, "similar_positions": 414, "identity": "15.92%" }, { "cls_id": "homologset.agr.HGNC:32327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D6I9-1", "uniprot_id": "LURA1_MOUSE", "id": "Q9D6I9-1", "name": "Leucine rich adaptor protein 1", "aln": "MEGTAESQTPDLRDVEGKVGRKIPEGLLRGLRGECELGTSGDVLLPGAPSTGHGLGDKIMALRMEL----------------------------------------------------AYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPGRSRRGSWDSLPDTSSTDRLDSVSIGSFLDTVTPRELDEQGLPGPSCPEIDWAKVIPTEDRARTEVDMTSTKLGSLTATWKLPGDGLQCGPPEPSEDGNANQGFEAHWYWGQCQDDVTFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0KXM3-1", "uniprot_id": "A0ABK0KXM3_RAT", "id": "A0ABK0KXM3-1", "name": "", "aln": "MEGTAESQTPDLRDVEGKVGRKTPEGLLRGLRGECDLGTSGDVLLPGASSTGHGLGDKIMALRMELPSASILGGDAVAVRESHCCRIKESGAQIGFLSNAVQLSLLSLGDQLGDQLRKAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPERSRRGSWDSLPDTSSTDRLDSVSIGSFLDTVAPRELDEQGHPGPSCPEIDWAKVIPSEDRARTEVDMTSTKLGSLTATWKLPGDGLQCGPPEPSEDDSAKQGFEAHWYWGQCQDDVTFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96LR2-1", "uniprot_id": "LURA1_HUMAN", "id": "Q96LR2-1", "name": "Leucine rich adaptor protein 1", "aln": "MEGTVESQTPDLRDVEGKVGRKTPEGLLRGLRGECELGTSGALLLPGASSTGHDLGDKIMALKMEL----------------------------------------------------AYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPGRSRRGSWDSLPDTSTTDRLDSVSIGSFLDTVAPSELDEQGPPGAPRSEMDWAKVIAGGERARTEVDVAATRLGSLRAVWKPPGERLQGGPPESPEDESAKLGFEAHWFWEQCQDDVTFL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.***************** ************:***** :*****.****.********:*** ***************************************************** **************:****************:* ****** **.. .*:******. :*******:::*:**** *.** **: ** ****..** .*: ******:* *********", "identical_positions": 199, "similar_positions": 25, "identity": "68.38%" }, { "cls_id": "homologset.agr.HGNC:3233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYP0-1", "uniprot_id": "MEGF8_RAT", "id": "Q9QYP0-1", "name": "Multiple epidermal growth factor-like domains protein 8", "aln": "MALGGALAAALALAFAVLGPLSHKVLAGDCKGQRQVLREAPGFVTDGAG--NYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPQGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQNHGQCKSP-GVCVCEPGWGGPDCGLQECSAYCGS--HGTCASTLGPCRCEPGFLGRACDLHLWENQGAGWWHSVSAGDPAFSARVGAAGAFLSPPGLLAVFGGQDLNKALGDLVLYNFSTNTWESWD-------------------------------------------------------------------------------------------LTPAPAARHSHVAVAWAGFLVLMGGELANGLLTNDVWAFSPLG-GGHWELLAPPASSSSGPPGLAGHAAALVDDIWLYVSGGRTQHDLFSSGLFRFRLDHTSRGYWEQVIPAGGR--PPAATGHSMVFHAPSRTLLVHGGHRPSTARFSVRVNSTELFHVDRRVWTTLKGR----DGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAYKVPPFVFQAPALDYHLDYCSMYTDHSVCSRDPECSWCQG--ACQSAPPPGTPSGACPAASCLGLGRLLSDCQACLAFS------------SPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGWWGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNASQPDKVSIVRSTTITLTPSAETDVSLVYRG--FIYPMLPGGPGGPGAEDVAVWARAQRLHVLARMARGPDTENMEEVG-RWVAQQEKETRRLQRPGSSRLFPLPGRGNKYAVEIRGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSLACSSYSSCLGCLADQGCGWCLNSATCHLRQ--GRAHCEDDGNG---ESLLVLVPALCPLCEEHRDCHACTQDPFCEWHQSTNRKGDAACSRRGRGRGALKNPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHS------------------EPRCRSCHGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLG---LPVALP------------------------ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGITHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCNFHSHCRRRGPGYCDECQDWTWGEHCERCRPGSFGNATGSG-GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQICSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRFGGLLPPGGGTARAGPG-LSYCVWVVSATEALQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSS--SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGICNQSLGVCICAEG-FGGPDCATKLDGGQLVWETLMDSRLS---ADTASRFLHRLGHTMVEGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAED-GGPGPSPRSFHAAAYVP----------AGRGAMYLLGGLTAG-GITCDFWVLNLTTLQWRQEKAPQSI--------ELPAVAGHTLTAR---RGLSLLLVGGYSPENGFNQQLLEYQLAT-TWVSGAQSGTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAK--------------------------------------------------------PRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNTWLLPDLTRPAFVGSPMEESVAHAVAAVGS-RLYISGGFGG-VALGRLLALTLPPDPCRLLPSPEACNQS-GACTWCHGACLSGDQAHRLGCGV--PPCSPMP---------RSPEECRRLRTCSECLARHPRTLQPGDGEASVPRCKWCTNCPEG-ACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLASKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRG--PESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGHCMEGGLSG-----------------PRDGLTCGRPGASWAFLSCPPEDECANGHHDCN-ETQNCHDQPHGYECSCKTGYTMDNVTGVCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSALGGGTCRPCHAFCRGNSHVCVSRKELEMARREPEKYSLDPEEIEAWVAEGPSEDEAVCVNCQNNSYGDRCESCLHGYFLLDG----KCTKCQCNGHADTCNEQDGTGCPCQNNTETGVCQGSS--PSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQPPPPPP---------PPPPPADG--------VPRVASDLGGLGTGSGSGSPV-----------------EPRVREVWPRGLITYVTVTEPSAVLVVRSVRDRLVITYPHEHHALKSSRFYLLLLGVGDPNGPGANGSADSQGLLFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD--------PAGPAPAWKPAGLPP----------------------PAFRRSEPFLAPLLLTGAG-GPWGPMGGGCCPPALPATTAG------------------------------------LRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGSGGAGGSGHGGGGGRKGLLSQDNLTSMSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60882-1", "uniprot_id": "MEGF8_MOUSE", "id": "P60882-1", "name": "Multiple epidermal growth factor-like domains protein 8", "aln": "MALGGALALALALALAVLGPLSLRVLAGDCKGQRQVLREAPGFVTDGAG--NYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPQGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQNHGQCKSP-GVCVCEPGWGGPDCGLQECSAYCGS--HGTCASTLGPCRCEPGFLGRACDLHLWENQGAGWWHSVSAGDPAFSARIGAAGAFLSPPGLLAVFGGQDLNKALGDLVLYNFSTNTWESWD-------------------------------------------------------------------------------------------LTPAPAARHSHVAVAWAGLLVLMGGELANGLLTNDVWAFSPLG-GGHWELLAPPASSSSGPPGLAGHAAALVDDIWLYVSGGRTQHDLFSSGLFRFRLDHTSRGYWEQVIPAGGR--PPAATGHSMVFHAPSRTLLVHGGHRPSTARFSVRVNSTELFHVERRVWTTLKGR----DGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAYKVPPFVFQAPALDYHLDYCSMYTDHSVCSRDPECSWCQG--ACQAAPPPGTPSGACPAASCLGLGRLLSDCQACLAFS------------SPTAPPRGPGALGWCVHNESCLPRPEQARCRGEQISGTVGWWGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNASQPDKVSIVRSTTITLTPSPETDVSLVYRG--FIHPLLPGGPGGPGAEDVAVWARAQRLHVLARMARGPDTENMEEVG-RWVAQQEKETRRLQRPGSDRLFPLPGRGNKYAVEIRGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSSACTSYSSCLGCLADQGCGWCLNSATCHLRQ--GRAHCEDDGSG---ESLLVLVPALCPLCEEHRDCHACTQDPFCEWHQSTNRKGDAACSRRGRGRGALKNPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHS------------------EPRCRSCGGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLG---LPVALP------------------------ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGITHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRRRGPGYCDECQDWTWGEHCERCRPGSFGNATGSG-GCRPCQCNGHGDPRRGHCDNLTGLCFCQDHTEGAHCQICSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRFGGLLPPGGGAARAGPG-LSYCVWVVSATEALQPCVPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSS--SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGICNQSLGVCICAEG-FGGPDCATKLDGGQLVWETLMDSRLS---ADTASRFLHRLGHTMVEGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAED-GGPGPSPRSFHAAAYVP----------AGRGAMYLLGGLTAG-GVTRDFWVLNLTTLQWRQEKPPQNM--------ELPAVAGHTLTAR---RGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAK--------------------------------------------------------PRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNTWLLPALTRPAFVGSPMEESVAHAVAAVGS-RLYISGGFGG-VALGRLLALTLPPDPCRLLPSPEACNQS-GACTWCHGACLSGDQAHRLGCGV--PPCSPMP---------RSPEECRRLRTCSECLARHPRTLQPGDGEASIPRCKWCTNCPEG-ACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLASKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRG--PESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGHCMEGGLSG-----------------PRDGLTCGRPGASWAFLSCPPEDECANGHHDCN-ETQNCHDQPHGYECSCKTGYTMDNVTGVCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGAQDHCLLCRNHTKGSHCEQCLPLFVGSALGGGTCRPCHAFCRGNSHVCVSRKELEMARKEPEKYSLDPEEIETWVAEGPSEDEAVCVNCQNNSYGDRCESCLHGYFLLDG----KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSS--PSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQPPPPPP---------PPPPPADG--------VPRVAADLGGLGTGSGSGSPV-----------------EPRVREVWPRGLITYVTVTEPSAVLVVRSVRDRLVITYPHEHHALKSSRFYLLLLGVGDPNGPGANGSADSQGLLFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD--------PAGPAPAWKPAGLPP----------------------PAFRRSEPFLAPLLLTGAG-GPWGPMGGGCCPPALPATTAG------------------------------------LRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGSGGAGGSGHGGGGGRKGLLSQDNLTSMSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7M0-1", "uniprot_id": "MEGF8_HUMAN", "id": "Q7Z7M0-1", "name": "Multiple epidermal growth factor-like domains protein 8", "aln": "MALGKVLAMALVLALAVLGSLSPGARAGDCKGQRQVLREAPGFVTDGAG--NYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQSHGQCQPP-GVCACEPGWGGPDCGLQECSAYCGS--HGTCASPLGPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPGLLAVFGGQDLNNALGDLVLYNFSANTWESWD-------------------------------------------------------------------------------------------LSPAPAARHSHVAVAWAGSLVLMGGELADGSLTNDVWAFSPLG-RGHWELLAPPASSSSGPPGLAGHAAALVDDVWLYVSGGRTPHDLFSSGLFRFRLDSTSGGYWEQVIPAGGR--PPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDRHVWTTLKGR----DGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAYKVPPFVFQAPAPDYHLDYCSMYTDHSVCSRDPECSWCQG--ACQAAPPPGTPLGACPAASCLGLGRLLGDCQACLAFS------------SPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGWWGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNTSQPDKVSIVRSTTITLTPSAETDVSLVYRG--FIYPMLPGGPGGPGAEDVAVWTRAQRLHVLARMARGPDTENMEEVG-RWVAHQEKETRRLQRPGSARLFPLPGRDHKYAVEIQGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSSSCTSYSSCLGCLADQGCGWCLTSATCHLRQ--GGAHCGDDGAG---GSLLVLVPTLCPLCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHS------------------EPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLG---LPVALP------------------------ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSR-GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPG-LSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSS--SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGTCNQSLGVCICAEG-FGGPDCATKLDGGQLVWETLMDSRLS---ADTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAED-GGPGPSPRSFHAAAYVP----------AGRGAMYLLGGLTAG-GVTRDFWVLNLTTLQWRQEKAPQTV--------ELPAVAGHTLTAR---RGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRGLGQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLLPDLTRSASVGPPMEESVAHAVAAVGS-RLYISGGFGG-VALGRLLALTLPPDPCRLLSSPEACNQS-GACTWCHGACLSGDQAHRLGCGG--SPCSPMP---------RSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEG-ACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRG--PESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSG-----------------PRDGLTCGRPGASWAFLSCPPEDECANGHHDCN-ETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDG----KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSS--PSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQPPPAPP---------PPPPPADG--------GPRGAGDPGGAGASSGPGAPA-----------------EPRVREVWPRGLITYVTVTEPSAVLVVRGVRDRLVITYPHEHHALKSSRFYLLLLGVGDPSGPGANGSADSQGLLFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD--------PTAPASAWKPAGLPP----------------------PAFRRSEPFLAPLLLTGAG-GPWGPMGGGCCPPAIPATTAG------------------------------------LRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGGGGAGGSGHGTGAGRKGLLSQDNLTSMSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QBZ9-1", "uniprot_id": "F1QBZ9_DANRE", "id": "F1QBZ9-1", "name": "", "aln": "-----MTFHIQTLLLPVLVVLVPAVWAGDCKGQRQVLRAVPGYVTDGPG--NYSVNGNCEWLIMAPSRNHRIVLNFMFIDTECTYDYLFVYDGDSYQSPLLASLSGKTLPQPIEAKSGKMLLHLFSDANYNLLGFNATYTFSVCPGDCSGHGRCDVATARCQCQQGWGGLDCNTPLCSQACTQRGHGICDKRGLKCICSSGFVGQDCQLGLRDNSGAGQWWEVSSGDVKAAPRTSSAGVYLASTGAMYMFGGFDLNRALEDLVVYNFSTNSWEQMT-------------------------------------------------------------------------------------------FSHSPAPRHSHTAVEWQGSMVIYGGELANHSLASDVWIYRPQ--QNEWQQLG--LSDAPGAPRLANHAAAIVD-HYLYVFGGRTEEDMFSSSLYRFRLRN---GVWEAVQPTGGK--PPATAGHSMIYHSPSKTLLVYGGHRPTTARFSVRVNSTDAFHVEKRFWTSFRSR----FPANGPRERAFHSATVIGNYMVVYGGNVHIHYTEEKCYDEEIFFYHLGCHQWVSVGDSLGQ-----RGVSVRGRYSHVAAVMEGRVLLVAGGYSGIARGDLVAYKVPLFVSSDPGD--RDSVCAEAPSESLCLKNPECSWCEG--RCREYQP----TDPCGSTGCLGLARFLSDCQSCLVFSG-----------VPNSLPRVSGEFGWCVQNESCLPVSEHSACRVDQISGAYGWWGERTRFLTSLPFCRTENYVPGLHLLTFQHPRNQSQPDKVSILRSTSIILNPSTEMDVTLQFRG--FIHPLWSSPP---HQETVAMWARIQKLHFTAQMAAGPNSLQLTDVLGRWSAQEEKDIHKLSRSDGSRLFQNLTRGNWYLIQAEGYLNNSASGQTSEMALTWNRTGLPGGSEISFLFLEPFRSNSCSEYRSCLACLSDQSCGWCPTVNLCFLRSDINQQPCIDPQGE---ERHLLLNPLHCTLCEEYRDCAACTQDPYCEWQINSSKKGDYLCSRRGRLEGSIREPGGCPNVCNQRLTCGECLSNSSQCAWCESAQSCFYFAAYLTKFPYGECRDWYDSVHS------------------VPQCKQCTALTTCSECLQTFQCGWCGDYSNPTIGRCLRGDWGGMNDHSAVNCSTAVAEVKATSPEPQTLSPPRLMELEMDLEMEQLEGMEGDGDAVWSYPSCPDVEECRLGLHTCHPSATCVNTPTSYECHCERGFTGDGVHHCNQTCYNECRQGRCSGSPLFECECSLGWTSDPATLVLS----GVECDVDCGCNFHSTCIT-APGICDQCQDWTTGPHCEHCKPGSFGSALARGDGCVPCQCNGHGDPLQGFCHNQTGQCYCTHHTQGPHCESCLPGYYGDPRDNGTCFSQCQGRSVLLSSSVPLSLSSSLGWHGAVGGHGGVGGHGGLSHCLWVLSVSQDLAPCMPGQSCPPVALTWHPDSHTHCTNSYVYVFDGLPRFLSNGVVHSHHNLIGAFCGTTRMEPITVEATSGVVSVYFEANVTSGRAQGFNASFWVKRCGNGSTDEGTVISAECQAGAQCINGLCECPHGLGGPQCDRPVCPGSCGAEEGRGTCNMNLGLCVCTEG-WAGSDCSSISDTDSLVWETLLDTQLS---VNKAHRFLRRMGHSLMSSPQGTLWMYGGLSLSEGILGNVYRYSVADRRWTEVLTSSVE-ESSMPLPRYHHASALVYYQFPISGSHSATRNLMFVVGGVTKE-GVANDTWCLNLDSQEWKQYKSS-----------VLPPVAGHTLTVR---KGSSVLLIGGYSPENGFNHHLLEFSPQSGNWTIALHTGTPPTGLYGHSAVYHEQTDAVYVFGGYRFHVEAVEPSGELYSLYYPNLTWSLLVPSQGNK--------------------------------------------------------PLSRFFHAAALVKDTMVIVGGRTGEEDYSNTVSLYQINCNTWIQPVSS----VGEPVNSSVSLAMTVWGD-RLFLSGGFNG-VTLGRFLTLSLPSDPCILLPTPEACNSSTGSCVWCRGTCASSDAAERLGCTLGLSTCSPTP---------RSPDQCRRLKTCSECLARHPKTFSSP--VQSALQCKWCTNCPEG-ACISSSVSCTSEHDCRINQREIFLSSNCTETSCEASDCPKCTASGKCMWTRQFKRTGETRRILSVNPTYDWTCFSYALLNVSPMQVESSPPMPCPEPCHEIKTCSQCLSSRGSDGGWQRCVWSMALQQCMSPSFVPLRCEAGQCGRLLSD--EDSCSPQCFQLTQCSQCISRPQCGWCAGRGGNGSGRCLQGGLNG-----------------VSEAL-CPQWNSSWSFLHCPEEDECSNGHHHCN-VTQDCHDLPEGYHCTCRQGYVLSSVSGQCEPVCAQGCVNGTCISPGICQCHFGFVGENCSSQCRCNKHSNCKSISQLDTCLECKNNTKGQHCDKCKPLFVGSAMGGGMCRPCREFCRGNSDICLSKDEHNKAMENPKDYPLDRESIEQWATEGPTEDHAVCVSCQNNSVGDKCESCLSGYFLLQG----KCEKCQCNGHADTCNEHDGTGCPCQNNTETSSCLSSP--QNDRKECYRQQCAKCKESFNGNPVNGRQCYRQFNVDSECCFDPTSQVNCFHEPNIRNLLRGRTVFFSAQPKFTNVDIRVTIDVTFGEVEVYVSNSHDTFIVQVDRQSGVHTIKIEDEATSATASRGEKEVPLAPPSPM--------KVFANSSSALLGTLSAKLQGS-----------------EREVREERAEGLITYITVWKPQTVLIVRGVRDRVVITFPHEVHSLKSSRFFIALRGVGTETHNGE-----SQGLLFLRQDQAHIDLFVFFSVFFSCFFLFLSVCVLLWKVKQFLDFRREQRRHIQEMTKMASRPFAKLTVYLEPEEPQLVYLPSAGGGSAVSLAHVRTGKLGGMVMGQRGRPGALSYKHDPGTGTATHHHHHLALSGGNNGQHLPLHYLNAHHYAPSSTANPTSHHQHHYPSSHGSYQHFCRSDPFLSQLMGFSYSSFKVGPITLEPTDDGMAGVATVLIQLPGGILAPNRACLGSALVTLRQNLQEYCGHGG--AGTHPGAGGGRKGLLGHQHLTTMAM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT6-1", "uniprot_id": "Q9VLT6_DROME", "id": "Q9VLT6-1", "name": "", "aln": "MYALLATLTFWTLVLQTEQAHPSTSPSAPCDRSRKVFTEPYGEISDGPSGFNYTQDSHCEWLIKARNDSQYITLTFHSMGTECSYDYIYVYDGDSFNSTLLGSFSGRTQPQRLVARSGSMLILMYSDTNYVLDGFRASYYISNCLNNCHNHGKCVGH--QCVCHGEWVGPDCEDEACPQRCGE-SQGRGRCQKSICHCSRGYSGRLCDLSDHPAGSS--WRWLATDAEGMTARAAHSAVYMEDEDALYVFGGYDLNNVISTLQIYRFSTSQWEDEWGIALQSRRHFYHPQKIDHTLLKAVLQHKNEDEAKLWGLNSDVSFFRNILYTLAESNLHQRRTRSSLPLTIVNANSTDEELNEYLEDILEEVTDHKPHGRYGHAADSVPGGFVIYGGKHANGSFYSDLWQYNNTESGGKWKQMA--IRSAVKPPALARHTLNTAG-SYLYIFGGSLETGEFSSSVYRIPLPLSEDSQWELVQPRGGKTLDVRLAAHSTVYYKATNSLIVFGGIMTSLARFSKLSDRIYAFQLDQMHWTEILYPRTALRDTNIPRERAFHTATISGNYMVVFGGYTHRHNKDEICYDNQMYWYHLSCHIWINQVVSADDS----LYPKPQGVFAHAAALRRNHTLLIVGGYHGNVNADLFAYELPQVLRVENTLYNPEISCRLHSSHTACLSNPECGWCSADSSCYGRTIGANCTTNLQTTRCPGICPSLGDCHSCLVHGSQWGKSSGNKAAFSVASKLGLNECTWCVQNAKCHHRDDNYGICGD----SSGWWGDKGTEIRRPSLCTSTDRRPGLTYIKYHFPINYTMPDYVGIVNATMVDFASPPFTTYFEHKLEGEMLARLVGFVRPQHQWNNSAIQVCTSYSSAVLRAGLGLNLDELVNVTTQSSNQSYCSNVQLPTTEQPFTIDFQTRRR---IGGNGIYN---AYQKTKMELQHLHNGQLN--AFTFEYLEPYYSGKCTQYSNCLHCLTDASCAWCPLTNICHLRSVNETEVCKMETLDTFHWSYLISQPSQCSNCTNYVSCEACARSGECEWWTEDAR-----CGRIGKTNSSVRAVEHCPRSCRERHGCQECLGERGRCVWCEASAQCFSFSVYTSEYQFGMCREWVDQVVSRQTQEIADHKPQQTPHFLQQQCKSCEQHRNCSSCLRTLSCGWCFDRDNPIEGICMQGDFSYS----AGNCSLALNSSSHH-------------------------------DAEWAYAQCPDVDECGLGLHDCHKEAKCTNTQGSYNCHCRRGYIGDGKFSCVRTCYELCQNGNCSGPPDYTCRCALGWT-------------GADCGLSCGCNNHSTCNE-RLGKCDQCQDWSEGEKCERCRQGSYGNATAPH-GCLPCECNGHGNQDLGVCNVSNGECYCKDNTQGLNCELCAPGYYGDPRGGGKCYYQCESRGILTNIGKSAIGSYQS-------YRSPWGASLEVKECLWILQP----KTLQAEKSLLQLEFQWQS-LAMDCDENAVYIYDSLPDLTG----ATQQNQLLAVVCAPYSSPRIIEARSSHVTVHYKQGSER-RHFGFNALYSVMNCVAG---------SCISPHICDAQQRCVCPAGYVGASCEIEICPSNCNAKRMQGFCDTEYGRCICSNANYAGADCGTLVQRNHLVMTELFNTQLLSESLEHLRKTIPRFGHSVNADRRGSLWMFGGYSPNHGPLNDFRQFDTKNSTWLQVTVESSTPEDRMPLGRYFHASEIYVK-----------KQIIYIYGGIGANSQLLNDFWMFSIQNQRWSQIKVEVEPPEADYEVDVPPPLAGHTLTHIRYQEHESLILLGGLSLNKSRPLELWEFNLDTGRWQQLAAVGARMPVLYGHTSVYHQETNSVYLFGGY-----STEPQSNLYALDLQKLSWTELPSFRELN--------------------------------------------------SPASLLPRARYFHSAVTTEHYMILYGGRTQPFNGTDVLIAYVYACNQWVRLTEDVELIGRVPASSYAEDMAIDPDTGAIYVIGGWDGSSTHSHVTKITLPDDICQLWSNGKYQCRHYMGCSYCTIQNTYSYSSHCFSHGR--TPCANHNGTLVVNNGAACDDDWMASRNCSSFATCGACLAAWPTHQEVAPVCHWCDDCGIRGRCVPAGVDCGRRSAWCNKELSVGVLGLCPLPQCYQLSCESCMLQPQCNWARNELGT--------------VECIAKELVEKNQYRVVES----CPLPCHTYENCSLCLS-QTPTQDHQECKWSTMLNLCLTPSSQPLLCAGGVCGLVLEASELQRCPEPCHVYTQCSSCLEHAHCGWCAREGFNGDGICTEGALEHKQEHPSGSTCDLIYASWRNDSQLTHADVVSWHYVQCPAENECINGHHNCDTVSEQCIDLDTAVGYKCVCAQGYREEQGACLPVCSQGCVRGNCVSPDQCQCDFGYVGANCSIQCLCNGHSNCESSSRLDICLKCHNNTMGEQCEKCQPLFVGNPREGHACQPCLDYCHGHSDVCVAYD------ADPAVFNMTRSELERILQEGPAYN-ATCLRCGNHTAGDRCDSCLTGYFRGSEDLHKECRPCQCHGHGNICDPVTGEKCNCANNTESDATCTAGGGKNSAQLCWMVQCSKCRDSYAGNPTDGHQCYKQITVESRMCFDAKPIEECKSKP--AALKPGQTVFFVIQPRFMNVDIRIIIDVTQGELDVFMSPQDDSFIVETNETTGYHEIFLDNRYNWGPKIKREHPLNVALPRHDNVTIQKLFSPERRIGGGGLGGGGGERIGANTYYVPQLQDCKSHGGHNFIVKDQHAKDLSTHVTLNHCNTLLRLFGLKNRLVLTLPQHAHNLSATRFFIALRASSGPE--------PSYGSVVFRQDQLHIDLFVFFSVFFSCFFLFLAVCVIVWKVKQAADLRRARRQHVVEMLHLAKRPFAQIFLASNGLDMD-----SPQPTSSSSSARAMR----------------------------QRARQALLLQEQSAGDSQSVMHHSTRRQS------------------------------------------SRIMMVAIEPTFDNLAAVGTVFISLPGRSRAPLSIALGSTLISYSRQYPLNTRHFMRAQRGQNVANHPA--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : . :. *. .*:*: * ::**.. **: :.:***** * . .: * * * :.***:***::****** ...**.*:** * * : * **.**: ::**:** * **.*:: :* * ..* .**:* * *. * * ** *. * . :* * *. *: *: *:* .: * ::: :.* . :..:: . : :*** ***..: * :*.**:. **. * *:.*.* * :*: **: *: : .*:* : ..*: :. .: .* ** *: .. :**: ** . ***.::*: * . ** * * **: :.** ::: .:.:*:*.** .: **** : *:::: ** : : *******:*:: ******:** .* * :* **:: :::***.** *:. * ::*.**: . .**:.*** * ..**.**::* .: * ...: * :***.**.. * :: * *: *.**::**... . : . ***:* .* :: : : **** : * : . *** :.:: * * : ** *.*:.:* : : ... :: : : *: . . : . * : :: :* : :. . :* . : * . : .* * . ::: * :.* . ::* :***: * *:.* .** **:* .*.** *.**. * *: * *. * :: .* **::. *** . : *.* *: ..::: ** * :* * :**.: .:*.**::: ** *:.* :.: .* ** * *.* * :*:.* .* .**:: .**** : .** * *::**:. . *** : . * *:*. ****:** *** ** *.* ** **:***.**: *** * :** : * :* ***.* : * * **** . *. .***. ** * * **:****: * :**:*: **:*.* . ** **:*****: * *. .* *:* .:*:* :*: * ******** .*.*: :* .*.:* . . * .. :. *:*::. . . : : : . * . * :*.:* : . :.:. : *. * ::* *. : :::: . **** .* * * ** * *. * :** .*.*. * *: . * *:*::. :.*.**.: : . ** *::::* : : : *:**:: . .:***:** . .* *.:. ::.. : * :: . : . * * .**: : ::: **: : * * :.: . .* * * *.:****** . *::*:** * ::. .* *:. : * *: . ****::***: *:::*:***: . *. :**:* . :*: * . : : * .* **::. . *:: ***: : :. : * ** *: * .. . . ::: **:.* : .:. ::** * * * .. : .* :* . :. :. ..*: . :: :.**. : . *:** :* *: . .* . :: .: . *. . * .* .* . :* *:*: * *:: *:: . * .* ** *** .*: ** : . . *.* ** *: *::** ** * .* ** :* : *. * ***: *: :.:***** * :*.* * :*.*. :. ** :: ** *:** ****.*: :::* * . .* . . * * ***:****.*.*:.*. *:*.**:** *** :* ** **:* . . * ** *:*:* *.:*::* *****.. * *:** :*:*:*.:*:: . :* : : ..:* ***: : *.*: * *:: *::*:*** *** . :* ***:**.: *: * * * ****:. : .. : *: **:**::*: *.* .*:***: :.*:.. *:*... :* :* * *:**:* **:* *****: :*** * :::::* . *:*:*.. :* * : :: . * . . * .. : *:: ...* *::*: . .::* : .:::*:*:* *:. * *.::**:: * . . * * :.:**** *******************::**::**.** * *: :*:*: ** ::*.****:: : .. .: . * * * . * .: : :::*** *.:*.*.*:::.*** ** .***:*:: :. . ", "identical_positions": 774, "similar_positions": 750, "identity": "24.26%" }, { "cls_id": "homologset.agr.HGNC:32331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNI7-1", "uniprot_id": "D3ZNI7_RAT", "id": "D3ZNI7-1", "name": "", "aln": "-----MPHSQESYPNPAVGDKDTHLGNLLAS-KKSTFKNPTHLVQQQDTWNRLSSASTATSIR-RDAYFYDPKIPKDDLDFRLAALYDHHTGAFKNKTEILLHQETIEDMQGTKLQFPGECFHSPSAPITSRTTIRHWINPK-------------KESIHSIQGSIVSP--HTAATNGGYSRKN-DGGFFST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAD0-1", "uniprot_id": "CF276_MOUSE", "id": "Q9DAD0-1", "name": "Cilia- and flagella-associated protein 276", "aln": "-----MLQPQETFSNPALRDEDKHLGNLWAS-KKSLYKNPAHLAQQQDPWSRLSSTPTATSRS-RDT-FFDSKIPKDDLDFRLATLYNHHTGAFKNKTEILLHQETIEDIQGTKIQFPGECFHAPSAPITSRTTIRHWINPK-------------KESIHSIQGSIVSP--HTAATNGGYSRKN-DGGFFST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T5A4-1", "uniprot_id": "CF276_HUMAN", "id": "Q5T5A4-1", "name": "Cilia- and flagella-associated protein 276", "aln": "-----MPPTRDPFQQPTLDNDDSYLGELRAS-KKLPYKNPTHLAQQQEPWSRLNSTPTITSMR-RDAYYFDPEIPKDDLDFRLAALYNHHTGTFKNKSEILLNQKTTQDTYRTKIQFPGEFLTPPTPPITFLANIRHWINPK-------------KESIHSIQGSIVSP--HTAATNGGYSRKK-DGGFFST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8Y5T1-1", "uniprot_id": "CF276_DANRE", "id": "A8Y5T1-1", "name": "Protein CFAP276", "aln": "-----MPQERDPFPFPRYEN-DFTLTGRKEI-QKLSDDKPTHLAQNDEPWRRLHNTTTEASSR-RTVFHYDTTTPKDSLDIHLKAAYDHHLGLFQNKSQTVMQMETVGADNGTKKNKE---LEDSVCDAENKG-IKVWVDTQ-------------KASLYSIKGSIESH--HTASTNRGYSRKH-DGGFYST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK88-1", "uniprot_id": "Q9VK88_DROME", "id": "Q9VK88-1", "name": "", "aln": "MIQYDTVQIKNVSWQPELHTEGTYVCSFPEPPLPEAHLKPGTWHGHLEPYQRLFYHQTMNSVRSSKRYRANPNIPKDTLDFSLQSRYDHTREAFPDKVDYVMQRETCRAISSWSAPGAAKEIGSQLKSFRVLRNTRFIRRKQEDVLGHPLRIGGCKEKIHPHSVKLICSGVHNQLVNNGFSRQTSDGNFFRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . : :* : :.: ** * * :. *** **: * : *:* * :* : ::: :* . : : : * .::. . .: . *. .* *:**: **.*: ", "identical_positions": 26, "similar_positions": 38, "identity": "13.54%" }, { "cls_id": "homologset.agr.HGNC:3234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3L3-1", "uniprot_id": "D4A3L3_RAT", "id": "D4A3L3-1", "name": "Multiple epidermal growth factor-like domains protein 9", "aln": "MNGGAERAMRSLPSLGGLALFCCAAAAAAS----AASAGNVTGGGGAEGQVVASPSPGLREQTSSPFSKAAAPTAQAPRTGPPRTTVHRTGAATPSAGSPETIP-VRTSAQPAATLFPV-VDLSSATPSEDGHTPTTEPLPSRPAPTTLASTAGQAPTTSVVTTAQASSTPGTPTAESPDRGRNSSRVPPTAPVTEAPTPPPPEYMCNCSEVGSLDVKRCNQTTGQCDCHVGYQGLHCDTCKEGFYLNHTVGLCLPCHCSPRGAVSILCNSSGNCQCKLGVTGSMCDQCQDGHYGFGKTGCLPCQCNNRSDSCDVLTGACLNCQENTKGEHCEECKEGFYQSPD--AARECLRCPCSAVTSTGNCTIEFGALEPTCDQCKDGYTGQNCNTCENGYYHSDSICLQCECHGHVDPIKTPKICKPESGECINCLHNTTGLWCEKCLEGYVRDLQRNCIKQEVIVPTPEGSTILVSNASLTTSVPTPVINSTFAPTTLQTIFSVSSSENSTS-ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDANEVAPNGQLTLTTPIHNYKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH27-1", "uniprot_id": "MEGF9_MOUSE", "id": "Q8BH27-1", "name": "Multiple epidermal growth factor-like domains protein 9", "aln": "MNGGAERAMRSLPSLGGLALLCCAAAAAAS----TASAGNVTGGGGAEGQVVPSPSPGLRDQASSPFPKTAAPTAQAPRTGPPRTTVRKTGATTPSAGSPEIIPPLRTSAQPAATPFPA-LDLSPATPSEDGHTPTTESPPSRPAPTTLASTVGQPPTTSVVTTAQASSTPGTPTAESPDRSSNSSGVPPTAPVTEAPTSPPPEHMCNCSEVGSLDVKRCNQTTGQCDCHVGYQGLHCDTCKEGFYLNHTVGLCLPCHCSPHGAVSILCNSSGNCQCKVGVTGSMCDKCQDGHYGFGKTGCLPCQCNNRSDSCDVHTGACLNCQENSKGEHCEECKEGFYPSPD--AAKQCHRCPCSAVTSTGNCTIESGELEPTCDQCKDGYTGQNCNKCENGYYNSDSICTQCECHGHVDPIKTPKICKPESGECINCLHNTTGFWCEKCLEGYVRDLQRNCIKQEVIVPTPEGSTILVSNASLTTSVPTPVINSTFAPTTLQTIFAVSSSENSTS-ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDANEVAPNGQLTLTTPIHNYKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1U4-1", "uniprot_id": "MEGF9_HUMAN", "id": "Q9H1U4-1", "name": "Multiple epidermal growth factor-like domains protein 9", "aln": "MNGGAERAMRSLPSLGGLALLCCAAAAAAAAVASAASAGNVTGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTP-LWATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLP--SSSNSSVLPTPPATEAPSSPPPEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPD--ATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTPTTLQTIFSVSTSENSTS-ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDGNEVAPNGQLTLTTPIHNYKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PS41-1", "uniprot_id": "A0A8M1PS41_DANRE", "id": "A0A8M1PS41-1", "name": "", "aln": "----MTCMRYTMLLFSVWELLLFGYTAGLSASDERRLPRAVLDETLEATTIPNHLQEDDRDSRFSPFTPAMTISNRDFRTTRNTNQVQSDWLTTTTTTT--------------------------TTPITTAELMTKTMNPTSEGSKVKENSTLSTTLNTTAKPTSSSPINDTKNTTPPALDTSNSTRTVKSTSNPPVVTTEKGLQCNCSTEGSVDPYTCDSVTSQCVCIIGYTGQRCDECEDEYFTNGTNG-CQPCDCHSYGAVSGLCNSSGMCNCKMGVHGDKCDDCLPGFMYFSSTGCQTCQCNNHSSYCHPQSGICVNCQGNTEGRSCEKCKYNFYRRPGSPVTEPCIPCPCSSVTSTGSCKLDSR-GQPYCVQCKPEYQGPNCEQCSDGFYNADSICLPCNCSGNGDPRLSPRICHPDTGYCLSCINNSTGPHCERCADGFTGDPLARNCTPTVVHTTPSSTTGWFLYTTMTSS-PNATTQFTSTTALLSSLASSTPNTTTTTTTVTPLPWNQFNIIILAVIIIVVIALLAVVGGVYTYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADISGLLEDEVSDMG-NGQLALTGPGSLYKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TEX5-1", "uniprot_id": "A0A8N7TEX5_DANRE", "id": "A0A8N7TEX5-1", "name": "", "aln": "-MWWLALMMFTSPAFPFIVFVCMGLTEAAHSYD--ALPLVIRKSRAVAEEHP----ETNADG-FSGHRLGIVALTPAPTITSARNPIN----VAAPAAT--------------------------IKPATTDPATPSPYNPSYMAAFARR------KLSSLETQMKVALMSDNR------ADRSAAVPDFSTTSD-----NSQELVCNCSGEGVSDPDECDRKTGQCDCMPGYTGLQCEECEEDHFTNGTIG-CLPCACDSFGAHGTSCDSSGMCTCKMGVYGPKCDDCHPGFFHFSSTGCQPCQCNNHSTYCHPQSGICLDCQDNTQGHNCEECLPSFYRRGGEGSADVCLPCPCSSETSSGICHLDSS-GRPVCAECKPGFTGPTCDSCTDGLFKSAGTCIPCDCNGNADPRSVPQICHPETGHCHRCVNHTTGAHCEICARGYTGDARRHNCTLRAVKVLPTTSVSSTPSSRLLTS-SSPTTN--PSLPTLQSGTGDSAGHNSTASALTVVSWTQFNIIILAVIIVVVVLLMGFVGGVYTYREYRNRKLNAPFWTIELKEDNISFSSYHDSIPHADPNGLLEEEPCVVAANGQLALATAANMYKA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. . : . . : . . :. .:..: : .* .. *: .. . .. . . . . . : ... **** * : *: *.** * ** * :*: *:: .: * * * * ** * . ** . *:*** * **:** * ** * *. *...** .*****:* *. :* *::** *::*. **:* .** . : * ****: **:* * :. .* * :** : * .*: * :* :: . * *:* *: ** *:**:*::* * *::::** ** * *:. * . . .: * :. : : :* .... : : . *.: . :.. .:*: ::: :.*.*******:***:**: *:..**.** ****:****************************:** .****:: :. ****:*: . **.", "identical_positions": 165, "similar_positions": 141, "identity": "27.14%" }, { "cls_id": "homologset.agr.HGNC:32348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUG6-1", "uniprot_id": "F1LUG6_RAT", "id": "F1LUG6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSSRQYRLSEVLQALEESRKLADADRGADQGLLGPFYNDVGMGYFQLQLFPLAVEAFLQALPLCRQAAEQATVLQNLGMTHNVLGNYWEAQEFHQKAVDLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSIRERLVAKLADATRTFVTQEKLAQAHFLPSVPGKLQTSWEASLEAKNSARVHSSAEDAQDS--------RSEEGREKK-KEGLMNMTIVLEPQRQDC--------------------------------------LGASEHLPSGGPWPRGVEHLVNTAPN----NRSSIGTKEALGRNLQRTSIQSGLCTIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYG0-1", "uniprot_id": "TTC24_MOUSE", "id": "Q8BYG0-1", "name": "Tetratricopeptide repeat protein 24", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQT----SRKAKTSARVQSSAEDAQESQ---WEGEASEGGHEKKEMEGLVNTATVLGPQRQN----------------------------------------RATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2A3L6-1", "uniprot_id": "TTC24_HUMAN", "id": "A2A3L6-1", "name": "Tetratricopeptide repeat protein 24", "aln": "MSSPNPEDVPRRPEPEPSSSNKKKKKRKWLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQACAFNLGAAYVETGDPARGLELLLRAHPEEKAQGRRHGDQCFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAAAGCMLKSGRHRVGEVVQVLEKSRRLA--ERSTERRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSSTAGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLSRSRQRRPMESGICTIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.* :: :.:*::.**:**:** :*.::: *** :***:*:** ******************* ..******:****:**.**** **:******..***************..***:*******:** *.********:*:**:*******************:************ **:**.*:**********: ** ::* :.*:: *.*.**:**: * ..*:. **: ..*. * *::** * * . * * : . *** ** * *: .*: .*** .:*:*.*. ** ::**:*:*:", "identical_positions": 191, "similar_positions": 77, "identity": "32.71%" }, { "cls_id": "homologset.agr.HGNC:32349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D5K1-1", "uniprot_id": "TMM81_MOUSE", "id": "Q9D5K1-1", "name": "Transmembrane protein 81", "aln": "MKTGAIVFILRSLLSITYLPLVLMT---LDIPEELQKAVGRVIVNATGCSVTCGLGYKEETECEVGPDG--VRRNCTFQRLECVTNWICGMLHFTIVHGKTFELNCLSSDILEKGQEAFRFTWRLARGIISTNDELFRPFRANSP-FIGFKPAYEYNAGTYRCDVQLLKNLKFVKRLYFGLRVLPPKLVNLNFQQSLTEDQKLIDKGWEVNLDNGSKPHLPVWQRKVTSALGIGIVAGVVGGVLVSVAVFKALGGTDGSGGRTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXW8-1", "uniprot_id": "TMM81_RAT", "id": "Q6AXW8-1", "name": "Transmembrane protein 81", "aln": "MKAVATVFICGSLVLITYLPLVVTSPQTLAIPEKLRQAVGRVVVNATACSVTCGLGYKEETSCEVGPDG--VRRDCRSQRLECLTNWICGMLHFTIIQRQQFELNCLSSDILTKGQEAFRFTWKLARGIISTNDELFKPFRANSP-FLRFKPAYESDSGTYRCDVQQLKNLKLVKRLYFGLRVLPPKLVNLNFQQSLTEDQKLAEEGWEVHLDNQSQPHLPGWRKKVSLALGVGIAAGVVGGVLVNVALCRVLGGTGGNGNLSSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P7N7-1", "uniprot_id": "TMM81_HUMAN", "id": "Q6P7N7-1", "name": "Transmembrane protein 81", "aln": "MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINATTCTVTCGLGYKEETVCEVGPDG--VRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSDILEFGQEAFRFTWRLARGVISTDDEVFKPFQANSH-FVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRVLPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKKKVASALGIGIAIGVVGGVLVRIVLCALRGGLQQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JI67-1", "uniprot_id": "TMM81_DANRE", "id": "B8JI67-1", "name": "Transmembrane protein 81", "aln": "-MALSTLWLVLMLWTSLFSDSQCSTLS-QAELQELEQIHTWVVSRSFPCSVTCGLGLLTQELCPIGVTRNISTSSCKLRTISCLDSWQCGLKTQTATVGRRLVLDCLEEVMEAMGRFSFVVSWRFAFAIITTDDSLFTRYEALSLDKVVLDPLREEDSGTYRCDVLDTG-KRRVKRMYKGVKVLSPKDLSLDFAQGLIH-WEIPESRFANLTSSRKVYSSSTIRNIVIISVPLSFAIAVVIFIFLFCYSRRARRAAHLCQDNI--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: * : : ::*.: *: .: *:****** : * :* .* : :.*: .* **: * : : *.**.. : *: :* .:*::* .:*:*:*.:* :.* * : :. * ::******* : ***:* *::**.*: :.*:* *.* . :: :. .. . . :. * :: :.:. .** ::: . ", "identical_positions": 54, "similar_positions": 80, "identity": "20.38%" }, { "cls_id": "homologset.agr.HGNC:3235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LS36-1", "uniprot_id": "A0ABK0LS36_RAT", "id": "A0ABK0LS36-1", "name": "", "aln": "-MQPPWGLALPLLLPWVAGGVG--TSPRDYWLPALAHQPGVCHYGTKTACCYGWKRNSKGVCE-------------------------------DVNECAFKPRPCQHRCVNTHGSYKCFCLSGHMLLPDATCSNSRTCARINCQYSCEDTAEGPRCVCPSSGLRLGPNGRVCLDIDECASSKAVCPSNRRCVNTFGSYYCKCHIGFELKYISRRYDCVDINECTLNTRTCSPHANCLNTQGSFKCKCKQGYRGNGLQCSVIPEHSVKEILTAPGTIKDRIKKLLAHKHTMKKKVKLKNVTPRPTSTRAPKVNLP-YSSEEGVSRGRNSGGEQKRKEERKRKRLEEEK-SEKALRNEVEQERPLRGDVFSPKVNEAEDLDLVYIQRKELNSKQEHKADLNISVDCSFDLGVCDWKQDREDDFDWNPADRDNDVGYYMAVPALAGHKKNIGRLKLLLPNLTPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEETKTEDGKWKTGKVPLYQGIDTTKSVIFEAERGKGKTGEIAVDGVLLVSGLCPDDFLSEEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJZ5-1", "uniprot_id": "EGFL6_MOUSE", "id": "Q9JJZ5-1", "name": "Epidermal growth factor-like protein 6", "aln": "-MQPPWGLALPLLLPWVTGGVG--TSPWDYGLSALAHQPGVCQYGTKMACCYGWKRNNKGVCEAMCEPRCKFGECVGPNKCRCFPGYTGKTCTQDVNECGVKPRPCQHRCVNTHGSYKCFCLSGHMLLPDATCSNSRTCARLNCQYGCEDTEEGPRCVCPSSGLRLGPNGRVCLDIDECASSKAVCPSNRRCVNTFGSYYCKCHIGFELKYIGRRYDCVDINECALNTHPCSPHANCLNTRGSFKCKCKQGYRGNGLQCSVIPEHSVKEILTAPGTIKDRIKKLLAHKRTMKKKVKLKMVTPRPASTRVPKVNLP-YSSEEGVSRGRNYDGEQKKKEEGKRERLEEEK-GEKTLRNEVEQERTLRGDVFSPKVNEAEDLDLVYVQRKELNSKLKHK-DLNISVDCSFDLGVCDWKQDREDDFDWHPADRDNDVGYYMAVPALAGHKKNIGRLKLLLPNLTPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEETKNEDGRWRTGKIQLYQGIDTTKSVIFEAERGKGKTGEIAVDGVLLVSGLCPDDFLSVEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUX8-1", "uniprot_id": "EGFL6_HUMAN", "id": "Q8IUX8-1", "name": "Epidermal growth factor-like protein 6", "aln": "-MPLPWSLALPLLLSWVAGGFGNAASARHHGLLASARQPGVCHYGTKLACCYGWRRNSKGVCEATCEPGCKFGECVGPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPGTIKDRIKKLLAHKNSMKKKAKIKNVTPEPTRTPTPKVNLQPFNYEEIVSRGGNSHGGKKGNEEKMKEGLEDEKREEKALKNDIE-ERSLRGDVFFPKVNEAGEFGLILVQRKALTSKLEHK-DLNISVDCSFNHGICDWKQDREDDFDWNPADRDNAIGFYMAVPALAGHKKDIGRLKLLLPDLQPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEKTTSEDEKWKTGKIQLYQGTDATKSIIFEAERGKGKTGEIAVDGVLLVSGLCPDSLLSVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E9Z3-1", "uniprot_id": "A0AB40E9Z3_DANRE", "id": "A0AB40E9Z3-1", "name": "", "aln": "MKHLTWISALSLLLSFTLGTAD----HRQRRQISVMSGLGVCRYGSRLECCYGWKKNTKGQCEAQCDLGCKHGECVGPNKCKCFPGYTGKTCSQDLNECGLKPRPCEHRCMNTFGSYMCYCLNGYMLMPDGSCANSRTCSLAHCQYGCEEVQSEVRCLCPSPGLQLGSDGKTCEDIDECATGKNQCPFNRQCTNTFGSYYCKCQPGYDLKYINGKYDCVDVNECTSNTHKCSHHAECINTLGSYKCKCKQGFRGSGFDCSVKP-FYHRSWDSSKGNTDVLVNAIPDFPSKTRILGKFENSIPEPVLTESPRQHLQPFDYDGEVYIGAPQETPVFPEEEEVEE--EEEEDTENQLE---DEELTSRGDVFS-----QDDFVSFYQSELELKEIQAAPLKERFLTDCDFDRGACEWVQDNADDLDWTIKYHPDGREYYLALEGPVGNRREQARMKLLLEDHMRQSSFCLRFDFRIEGPQTGVLRVKLDNS-AISIWERKQSQKQSWQSEQISISWTDSNPEAVVFEAERGRSGTGEIALDHVLLISGECSEDKTLDF-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* **.***.:. * . . : ***:**:: *****::*.** ** *:***..*****:***:**.*** *:**.*:**:**.:* *****: :***.**:. . :*:***.**:*..:*: * ******:.* ** **:*.**********: *::*:**. :***:*:***: ::: ** **:*:** **:*******::*.*: **. * :. : *. . :: : . . : *:: *.*. * *: :* :. : * * :** .: *:*: *: *. : * . ***** :: . .. *.. . .: .**.*: * *:* **. **:** : : :*:*: . .*:::: .*:**** : **.*** **:*: * :.* *** :.** **.. .:. *:: :: : . .::::******:. *****:* ***:** *.:. ", "identical_positions": 199, "similar_positions": 153, "identity": "35.79%" }, { "cls_id": "homologset.agr.HGNC:32350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R115-1", "uniprot_id": "TMM82_MOUSE", "id": "Q8R115-1", "name": "Transmembrane protein 82", "aln": "MFSLPSLSSWLPSLPSFEWGSSL-FDSLLQGLIGALGVSVLNSLLKVYFFVACVNDPQRQPQKQ-RLSAQWASLEMLHLAGLTLFLTLIGSRVAALVVLEFSLRAVSTLLSLGKGS-GNKERLQLFLVCQFSLGCGLSCGLSFLQEGAPHRSLNLLLSLGLAVLLALGARRLTRHICSLYELHSSQRYCGVCLGLLASQHGMPRLLSRTLTVAFAVSDLAAVALINKDFLSSSEAVRFWTPLTICYTLLVIYMQEE----------------------------------------------QWQHRFSLQGQVQTVLVRMGGLFLLLMTVGRWLDLLSIFFSLLGELWCLAGIRALIDLCQIQGFPPQRPTVTAAVTAEGESGWTDPCEPRPSTPAPARSAVPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L370-1", "uniprot_id": "A0ABK0L370_RAT", "id": "A0ABK0L370-1", "name": "Transmembrane protein 82 domain-containing protein", "aln": "MFSLPSLSSWLPNFPSFEWGSSL-FDSLLQGLIGALGVSVLNNLLKVYFFVACVNDPQRQPQMQ-RLRAQWASLEIVHLAGLALFLTVIRARVAALVVLEFSLRAVSTLLSLGKGS-RDKERLQLFLVCQFSLGCGLSCGLSFLQEGAPHRSLNLLLSLGLAALLSLGARRLNRHTCNLYELHSSQRYCGVCLGLLASQHGLPRFLGRALAVAFAVSDLAAVALINKDFLNTSEAVRFWTPLTICYTLLVIYMQGESPGAEVPSIGHTSQPPSPGTGLYCRLLRCHIGALKTRHLGLSSGLEEQQHRFSLQGQVQTVLVRMAGLFVLLMTVGLWLDLLGIFVSLLGELWCLAGIRVLIDLCQIQGFPPQRPTVTVAVTAEGESRWTGPSEPQPSTPAPARRAVPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0PJX8-1", "uniprot_id": "TMM82_HUMAN", "id": "A0PJX8-1", "name": "Transmembrane protein 82", "aln": "MFSLPSLPSWLPGLPSLEWGSSL-LDSLLQGLIGALGVLVLNSLLKVYFFVGCANDPQRRPEKE-RLRAQWASLETVHLAGLALFLTVVGSRVAALVVLEFSLRAVSTLLSLGKGSQGAAERLQLYLLCQYSLGCGLTCGLSFLQEGAPHRTLNLLLSLGLATLLGLGARRLHRHVCRLYELHSSQRYCGVCLGLLAHAHGLPQLLGRALAIAFAVGDLAAVALINQDFLTTSEAMRFWTPLTICYTLLVIYMQEE----------------------------------------------QRQHP-GLQSQVQTVLVRMGGLFVLLLTVGRWLDLLGILVSLLGELWCLVGVRTLLDLCQIQDFPSQRPPVST------------PSQPLPSAPQ-SQSSAPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WDB7-1", "uniprot_id": "X1WDB7_DANRE", "id": "X1WDB7-1", "name": "", "aln": "MLSF--LSWFVPSVPTWLTPNAIPLHSALQGLVGACGIWVLRNLLKTFLFVEAQSIADLDKDLKPKNKLNGGLTEKIQFWILTAVLSVVGSRVASLVVLEFSLRAISARITAGSDS-IIDPVLLLLVQCQFSLGCALTCSLKFLHEGAPQGWLSLSLAVGLSWFLATRCSRVWRHVNSMYPIHSTQRYCGLCIGLLTTGASILTWLCTALIITFSVSGIAAISNINQHFLSTTEALRFWTPLTICYSLLVVYMNED----------------------------------------------RRQQP--VQQIVNTVVVRLGGLFVLLITVGTWSDVLHVIICFIGEAACLLPSQDLLEAIYQHTSHEPKGQIK-----------------RPGNQGEHRKLGKFD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*: *. ::*..*: .:: :.* ****:** *: **..***.::** . . .: : : : : . * ::: *: .*::: :***:**********:*: :: *..* * * : **:****.*:*.*.**:****: *.* *::**: :*. . *: ** :* :**:*****:*:***: .: * :* ::*:*..:**:: **:.**.::**:**********:***:**: : . *: :* *:**:**:.***:**:*** * *:* ::..::** ** : *:: : : :. *. : ", "identical_positions": 128, "similar_positions": 113, "identity": "31.53%" }, { "cls_id": "homologset.agr.HGNC:3236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZB0-1", "uniprot_id": "A0ABK0LZB0_RAT", "id": "A0ABK0LZB0-1", "name": "Receptor protein-tyrosine kinase", "aln": "------------------------------------------------MGAAAQWFALPSSPSH-------LCAWISLPCCLSLGCCLA-----------VCQGTSNRLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAVLSNYGTNKTGLRELPMRNLQEILIGAVRFSNNPILCNMETIQWRDIVQDVFLSNMSMDVQRHLTGCPKCDPSCPNGSCWGRGEENCQKLTKIICAQQCS-RRCRGRSPSDCCHNQCAAGCTGPRESDCLVCHRFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGVSKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKG-----DSFTRTP---PLDPRELEILKTVKEITGFLLIQAWPENWTDLHAFENLEIIRGRTKQHGQFS-LAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKATNHVCNPLCSSEGCWGPEPTDCVSCQNVSRGRECVDKCNILEGEPREFVENSECIQCHPECLPQTMNITCTGRGPDNCIKCAHYVDGPHCVKTCP-----------------SGIMGENNTL---------------------------------VWKFADAN-----------NVCHLCHANCT------------------------------------------------YGCAGPGLKGCQQ----------PEGPKIPS--------------------IATG------------------------IVGGLLFIVVVALGIGLFMRR-RHIVRKRTLRRLLQER--ELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSN---FYRALMEEED-MEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSANSNSSAVACINRNG--SCRVKEDAFLQRYSSDPTSVLTEDNIDDTFLPVPEYINQSVPKRPAGSVQNPVYH-NQPLHPAPGRDLHYQNPHSN--AVSNPEYLNTAQPTCLS-SGFDSSALWIQKGSHQMSLDNPDYQQDFFPKEAKPNGIFKGPTAENAEYLRVAPPSSEFIGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01279-1", "uniprot_id": "EGFR_MOUSE", "id": "Q01279-1", "name": "Epidermal growth factor receptor", "aln": "--------------------------------------------------------MRPSGTAR-------TTLLVLLTALCAAGGALEEK--------KVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCS-HRCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKG-----DSFTRTP---PLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFS-LAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCP-----------------AGIMGENNTL---------------------------------VWKYADAN-----------NVCHLCHANCT------------------------------------------------YGCAGPGLQGCEVW---------PSGPKIPS--------------------IATG------------------------IVGGLLFIVVVALGIGLFMRR-RHIVRKRTLRRLLQER--ELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSN---FYRALMDEED-MEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSATSNNSTVACINRNG--SCRVKEDAFLQRYSSDPTGAVTEDNIDDAFLPVPEYVNQSVPKRPAGSVQNPVYH-NQPLHPAPGRDLHYQNPHSN--AVGNPEYLNTAQPTCLS-SGFNSPALWIQKGSHQMSLDNPDYQQDFFPKETKPNGIFKGPTAENAEYLRVAPPSSEFIGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00533-1", "uniprot_id": "EGFR_HUMAN", "id": "P00533-1", "name": "Epidermal growth factor receptor", "aln": "--------------------------------------------------------MRPSGTAG-------AALLALLAALCPASRALEEK--------KVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCS-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-----DSFTHTP---PLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFS-LAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCP-----------------AGVMGENNTL---------------------------------VWKYADAG-----------HVCHLCHPNCT------------------------------------------------YGCTGPGLEGCPT-----------NGPKIPS--------------------IATG------------------------MVGALLLLLVVALGIGLFMRR-RHIVRKRTLRRLLQER--ELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSN---FYRALMDEED-MDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYH-NQPLNPAPSRDPHYQDPHST--AVGNPEYLNTVQPTCVN-STFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04412-1", "uniprot_id": "EGFR_DROME", "id": "P04412-1", "name": "Epidermal growth factor receptor", "aln": "MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVT-YSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCTHG-CWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPG-HLLRDNGACVRSCPQD--KMDKGGE--CVPCNGPCPKTCPGVTV--------LHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYISNAYK--FDNRTCKICHPECR------TCNGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAKPDDYLQPKAAPGPSHRTDCTDEMPKLNRYCKDPSNKNS--------STGDD---ERDSSAREVGVGNLRLD---LPVDEDDYLMPTCQPGPNNNNNMNNPNQNNMAAVGVAAGYMDLIGVPVSVDNPEYLLNAQTLGVGESPIPTQTIGIPVMGGPGTMEVKVPMPGSEPTSS--DHEYYNDTQRELQPLHRNRNTETRV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..: . . .* :* **..:*: .. *.*: .*: :.** * ***::*:: . * *****..*:**:**:**: *::: : :******. :. : : : : : : * : :*:::* * * * ** **:: :*** :**.. : . *. * **. **.:* *** * :****::*: *: **: ** * .* :*** **.***** :.**:.*:.* ***..*: ***: ****** ::.******::******:** ::: *:*:***:* * ::::.* * *:*** *.* *: : ::* **. *: ** *.*:::** :* * .:* * ****.. :::.*******:* *:. : :* *.*** *:** .. *: **:* .: ** :*.**:**.*.*:*. *::***...*.* : . **. : .* . *: . :* *. :****. . :*::*:*.. . *: .*. :.. : .:* * ***** **.* *.*:* :*.* ** ***. ** * * ::*: .*::... **: **. * **:*** ..* ** : * * * :.*.:*. : * : :: * :: .:*.*:: : * *** **. ..* . ***:*::*::* *** **** ****:*:****:********** ::*..::.:*:* ***:*** :: :: :**.:*::* : ******* ********:::*:***: ****..******.***::**************:**. ************.::.:**:* ***:****:***.* :*::* :****::***:***:***.:*::.***.:*..::* * :* ** **::*:* ::.** :** **.*::* *:::**** ***.* **: :**: *..: : * * * : :...*:** *: . * *. * :..*. .:..: :* :* ** : : :* *** * . :*. . :* : : ** .* . * : . :*.***** ..*. :. * : : : . ::: . *..: : : . * .: : *: :. : ", "identical_positions": 463, "similar_positions": 367, "identity": "31.56%" }, { "cls_id": "homologset.agr.HGNC:32363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z5-1", "uniprot_id": "CHAC2_RAT", "id": "Q641Z5-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVE------------------------DPGGS-VWGVAYKLPVGKEEEVKTYLDFREKGGYRTTTVIFYPKDST-------------------TKPFS-VLLYIGTCDNPNYLG-PAPLEDIAEQIFNAAGPSGRNTEYLFELADSIRKLVPEDADEHLFSLEKLVKERLEGK--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQG1-1", "uniprot_id": "CHAC2_MOUSE", "id": "Q9CQG1-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVE------------------------DPGGS-VWGVAYKLPVGKEEEVKTYLDFREKGGYRTTTVIFYPKDST-------------------TKPFS-VLLYIGTCDNPNYLG-PAPLEDIAEQIFNAAGPSGRNTEYLFELADSVRKLVPEDADEHLFSLEKLVKERLEGK--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUX2-1", "uniprot_id": "CHAC2_HUMAN", "id": "Q8WUX2-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVE------------------------DPAGC-VWGVAYRLPVGKEEEVKAYLDFREKGGYRTTTVIFYPKDPT-------------------TKPFS-VLLYIGTCDNPDYLG-PAPLEDIAEQIFNAAGPSGRNTEYLFELANSIRNLVPEEADEHLFALEKLVKERLEGKQNLNCI--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KMJ1-1", "uniprot_id": "CHAC2_DANRE", "id": "Q4KMJ1-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYEDKRVGFVKGFSRRFWQGSTDHRGVPGKPGRVVTLIE------------------------DPEGC-VWGVAYKLPSGQEQEVKEYLDYREKGGYGVITVTFHPKDEQ-------------------QQPMQDTLLYIGSCDNPNYLG-PAPLETIAQQIVKSVGPSGKNTDYLFELADALRQLVPEDLDDHLFSLERLVKQLQEQEDMD-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYK7-1", "uniprot_id": "Q9VYK7_DROME", "id": "Q9VYK7-1", "name": "glutathione-specific gamma-glutamylcyclotransferase", "aln": "MLDFLTELRSSGSRADQLPGNIYTEFFANVIEEPREHGCKSADQDFTQGFSMLRTFDTENSNQLEPPAATDADVWIFGYGSLVWKTDFPYIDRRRGFVWGFKRRFYQHSIDHRGIPERPGRVVTLLPG-----------------------DPAQDRVYGVAYRIAASQKGAVLDHLDYREKNGYERCSLEFHEYPTDG------------------AEPIQ-VIMYVATQANDSYAGDVWQVPCIARQIFSSAGPSGPNREYLFNLAAAMDQLFPGAVDEHLEELVACVKRYIVEDEPQLIRHALLHEISGILEEEQLAEQAHQLEKLLERCQKPGGREWLIYAALQAKNKS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32656-1", "uniprot_id": "CHAC_YEAST", "id": "P32656-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase", "aln": "------------------------------------------------------------------MTNDNSGIWVLGYGSLIYKPPSHYTHRIPAIIHGFARRFWQSSTDHRGTPANPGRVATLIPYEDIIRQTAFLKNVNLYSESAPIQDPDDLVTIGVVYYIPPEHAQEVREYLNVREQNGYTLHEVEVHLETNREHEAELGEALEQLPRHNKSGKRVLLTSVYIGTIDNEAFVG-PETVDETAKVIAVSHGPSGSNYEYLAKLEQALAQMPIMKERGRITDHYLTALLETVNKYR------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::*****::* * .: . : .: ***:* * **** * .****.**: ** . **.* :. : * :*: **:.** : .: : . . :*:.: * : * : *. * : **** * :** :* :: :: :: . . ", "identical_positions": 48, "similar_positions": 48, "identity": "13.6%" }, { "cls_id": "homologset.agr.HGNC:32370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64017-1", "uniprot_id": "GP176_RAT", "id": "Q64017-1", "name": "Probable G protein-coupled receptor 176", "aln": "--MGHNGSWVSP-------NTSHP--RNTSG-----AQAG-ANSSAFGELSEAQL--YRQFTTTVQVVIFIGSLLGNFTVLWSTCRTTVFKSVTNRFIKNLACSGICASVVCVPFDIILSTSPHCCWWIYTMLFCKVLKFLHKVFCSVTVLSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAVTNVADIYATSTCTEVWSNSLGHLVYVLIYNVTTVIVPVAVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVTVFILCSVPYATLVVYQTVLNVPNTSVFLLLTAIWLPKVSLLANPVLFLTVNRSVRKCLVGTLVQLHHRYSRRNVVSTG--SGVVEPSLEPSMRSGSQLLEMFHIGQQQIFKPSEDEE-ESEAKYLGSTDFQAKEVLTSSPEGEE--SQLAPS--------------VPPPGTVDSVSRVSPVAPVEPGIFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLGNTPEELIQTKVPRVSRVERKMSRNNKVSIFPKVDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WT4-1", "uniprot_id": "GP176_MOUSE", "id": "Q80WT4-1", "name": "G protein-coupled receptor 176", "aln": "--MGHNSSWVSP-------NTSHP--RNTSG-----AEAG-ANLSAFGELSEAQL--YRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASVVCVPFDIILSSSPHCCWWIYTMLFCKVLKFLHKVFCSVTVLSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAVTNVADIYAMSTCTEVWSNSLGHLVYVLIYNVTTVIVPVAVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVTVFILCSVPYATLVVYQTVLNVPNTSVFLLLTAIWLPKVSLLANPVLFLTVNKSVRKCLVGTLVQLHHRYSRRNVVSTG--SGVAEPSLEPSMRSGSQLLEMFHIGQQQIFKPSEDEE-ESEAKYLGSADFQAKEVLTSCPEGEQEPPQLAPS--------------VPPPGTVDSEPRVSPVAPMESGIFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLGNTPEELIQTKVPRVNRVERKMSRNNKVSIFPKVDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14439-1", "uniprot_id": "GP176_HUMAN", "id": "Q14439-1", "name": "G protein-coupled receptor 176", "aln": "--MGHNGSWISP-------NASEP--HNASG-----AEAAGVNRSALGEFGEAQL--YRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVRKCLIGTLVQLHHRYSRRNVVSTG--SGMAEASLEPSIRSGSQLLEMFHIGQQQIFKPTEDEE-ESEAKYIGSADFQAKEIFSTCLEGEQG-PQFAPS--------------APPLSTVDSVSQVAPAAPVEPETFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLGNTPEELIQTKVPKVGRVERKMSRNNKVSIFPKVDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NID3-1", "uniprot_id": "A0A8M1NID3_DANRE", "id": "A0A8M1NID3-1", "name": "", "aln": "MEADNAESWFSQSENGTILNSSKLGFLNASSPVGLWGDAQDKEVTRLEEIVHAQERAYKDFTTTIQVFILIGSLLGNTAVLWCTIYTNVFKSVTNLFIKNLACSGICAGLVCVPFDIALSASPLCCLWVHTLLLCKAIKFLHRLFCSATVLSFAVIALDRYYSVLYPLERKISDARSRDLVIYIWVHAVLASVPVFAVSNVTDVYATSSCSD--GQSLGHLVYMITYSITTLILPLAVVFLAMVLIRRALSTSQKKKVIIAALRTPQNSISIPYVSQREAELHATLLSIVLVFTLCSTPYAALLIYHAILGAAKASSWLRLTAIWLPKVSLLTNPLFLLTVNRSVRRCLLDMLARLHRRYSRRNMVSIGGLAEVGPLGGETVVRSGSQLLEMFNIGQQQIFRPNEDEEDENEISSVASANFQPKDEGQGGNAGATDNTHQPQPGEGVKEEVLVLPKHSPIQSCAYSSSQVAPATPTDP-----EDATQFGFGPFELPPQWLPETRNSKKRLLPPLGNTPEELIQTKQPRV-RPERRISRNNKVSTFPNVDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: **.* *:*. *:*. .:* : : : *: .** *::****:**.*:******* ***.* *.******* ************.:******* **:** ** *::*:*:**.:****::***.*:***..********************:**:**:***.***:********:**:*:** *:*:: .:*******:: *.:**:*:*:.**** ::*******:****************:*****.*************:* ** ***.***:*::*:::*....:* :* ***:********:**:::****:***:**:. *.:**:******:** * : : . *. :**********:*******:*.**** *.* . :.*::**.*: * .: . . * . . * .:*:*.:* :. : : **************.************************ *:* * **::******* **:**.", "identical_positions": 318, "similar_positions": 126, "identity": "57.71%" }, { "cls_id": "homologset.agr.HGNC:32371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0N8-1", "uniprot_id": "TMM88_MOUSE", "id": "Q9D0N8-1", "name": "Transmembrane protein 88", "aln": "---------------------------------------------------------------------MAEVPGAQRPVLAGGPEP---RDPLDCWACAVLVTAQNLLVAVFNLLLLALVLGTILLPAVIMLGFGFLCHSQF-LRSQAPLCTSHLRDPGFTALLVTGFLLLVPLLVLALATYRRLCLRLRLADCLVPYSRALYRRRRIPQPKQIP-VSPGSRSVPTPG--KVWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7A2-1", "uniprot_id": "G3V7A2_RAT", "id": "G3V7A2-1", "name": "", "aln": "---------------------------------------------------------------------MAEVPAAQRPGLAGAPEP---RDPLDCWACAVLVTAQNLLVAVFNLLLLALVLGTILLPAVTMLGFGFLCH------SQAPPCTAHLRDPGFTTLLVIGFLLLVPLLVLALATYRRLCLRLRLADCLVPYSRALYRRRRIPQPKQIP-VSSSPRSVPTPG--KVWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PEY1-1", "uniprot_id": "TMM88_HUMAN", "id": "Q6PEY1-1", "name": "Transmembrane protein 88", "aln": "---------------------------------------------------------------------MADVPGAQRAVPGDGPEP---RDPLDCWACAVLVTAQNLLVAAFNLLLLVLVLGTILLPAVTMLGFGFLCHSQF-LRSQAPPCTAHLRDPGFTALLVTGFLLLVPLLVLALASYRRLCLRLRLADCLVPYSRALYRRRRAPQPRQIR-ASPGSQAVPTSG--KVWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F115-1", "uniprot_id": "E7F115_DANRE", "id": "E7F115-1", "name": "", "aln": "MRLTYQGLQQGKIRMSMNDTLEKGAHHQTIDLSEELPSISHHHQHHHPNLQHTNSLASTLPAGTAVGGSAVVVPPPYSPEAGGSEAPLELRGSLDCWACSVLVTAQNLLIAAINACLAGLVFGLILTPAIVMVVFGFLCHSTVRPHGSIPYCSDLLTDGGCVALLVVGFLLVTPLLVLALAAYCRLARHLQLGLCFIPYSRAVYKNLPATQHCGLAGGCCGQRSMKGAGKGKVWV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** . . ... * *..******:*********:*.:* * **:* ** **: *: ****** .. * *: * * * .:*** ****:.********:* **. :*:*. *::*****:*:. .* : . . ::: .* ****", "identical_positions": 74, "similar_positions": 40, "identity": "31.49%" }, { "cls_id": "homologset.agr.HGNC:32372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLN5-1", "uniprot_id": "D3ZLN5_RAT", "id": "D3ZLN5-1", "name": "", "aln": "MLYSLFLVPSLLLLVMPGPSRGWSRPLWYQVGLDLQPWGCQPNN----------LDNCRNSLGCPGYWMGLGGSRIYPVAGVTITTTMMLVISRVMLHRWRAKVAKGQLPQVTTNSCKHWKRQPTVSDRTLVLRVLHMLDAILLHIEGHLQRLASQQQIQIKGSPPASG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DA04-1", "uniprot_id": "TMM89_MOUSE", "id": "Q9DA04-1", "name": "Transmembrane protein 89", "aln": "MLYTLLLVPSLFLLVMPVPSQGWSRPLWYQVGLDLQPWGCQPNSPDIWGCQPNSLDSCKNSLGCPGYWLGLGGNRIYPVAGVTITTTMLLVVSRVIVHRWRAKVAKGQLPAVTSSSGKHWKEQPTVSDRTLVLRVLHMLDAILLHIEGHLQGLASQQQIQIKGSPPQSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RUT3-1", "uniprot_id": "TMM89_HUMAN", "id": "A2RUT3-1", "name": "Transmembrane protein 89", "aln": "MLHVLASLPLLLLLVTSASTHAWSRPLWYQVGLDLQPWGCQPKS----------VEGCRGGLSCPGYWLGPGASRIYPVAAVMITTTMLMICRKILQGRRRSQATKGEHPQVTTEPCGPWKRRAPISDHTLLRGVLHMLDALLVHIEGHLRHLATQRQIQIKGTSTQSG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * :* *:*** . .::.********************:. ::.*:..*.*****:* *..******.* *****::: ::: * *::.:**: * **:.. **.:..:**:**: *******:*:******: **:*:******:.. **", "identical_positions": 87, "similar_positions": 50, "identity": "51.48%" }, { "cls_id": "homologset.agr.HGNC:32375", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQPPEQSALPTAASYFAQNESEHNGGLADASSLQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQNQLRLEQLQQHCQDQQSTGEQQRQQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDESSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFKEASQVQP-SKEETSEQKALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHENVELQRQQLMLQQQLDRLRHYEAKAYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHNHHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLPTAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLGVELPADAAQAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTEQPSHNHAGDHLNCCMGKFEVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NN73-1", "uniprot_id": "GOG8C_HUMAN", "id": "A6NN73-1", "name": "Golgin subfamily A member 8C", "aln": "---MAEETRQSKLAAAKRKLKEYWQRNS-----PGVPAGAKRNRKTNGSIHETAT----------------SGGCHSPGDSSSTSSSLHAPQSPCQELAVVPDSRSVKVS--------QLKNTIKSLKQQKKQVEHQLEEEKKANNEKQKAERGLEVQIQRLN-------IQKGKLNTDLYHTKRSLRYFEEESKDLAVRLQHSLQRKGELERALSAVT---ATQKKKAERFSSRSKARMEWKLEQSMREQALLKAQLTQLKESLKEVQLERD-------EYAEHLKGERARWQQRMRKMSQEVCSLKKEKKHDKYRVETLERSLSK---LKHQMAEPLPPEPPAVPSEVELQHLRKELERVAGALQAQVEYNQRISLLNEGQKERLREQE---ERLQEQQERLREQEERLQQLAEPQNS---------------FKELNNENKSVLQLEQQVKELQEKLG------KRLAHPVASAQKEPEAAVPAPGPGGESSGFMDHLEEKADLSELVEKEELGFFQYYRERCHQKVYHPITKPGGSAKDAAPGGG---------------HHQAGPGQGGDEGEAAGAAGDGVAAGGDYKGHSKFLVTAQNPAHEPSPGAPAPQELGAAHKHGDLCEVS-LTDSVEPVQG-------ETREGSPHDKPTAQPIVQDHQEHPGLGSNCCVPFFCWAWPPRRRR----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::: .*****::***** ** * **. . . :::.* . :: :** :.* :*: .::: : .*. .:. . :.*: *::. **: :..:: :: * :*** : ::::* . *: : * : * .:*:::* ::: .:: :.. ::* .:*::* *:: **:: ** : : * .::*..*.. : ::*. :: * : : *: :*: : :: ::: :*.:* .** *: ::* ::*: : **::.::: :* :***.:.* *: *: *. :* : . * : *:.** : :: .:.:.* :.*.::*: :: :.*::* ***: :: .:* . :* ::*:: :: .:** :: ** :*. :.: : * ::: :* .*. :.* : : : .:*: :::*. :::*. :.:: .. .: *..* : . . :*. * :..*...: .... *. :.*.: . :. :* . *:: * * * : .*. :::** :*. :. : : ..:. : ::* :.* :*. .: :*. ", "identical_positions": 115, "similar_positions": 269, "identity": "14.45%" }, { "cls_id": "homologset.agr.HGNC:32376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQPPEQSALPTAASYFAQNESEHNGGLADASSLQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQNQLRLEQLQQHCQDQQSTGEQQRQQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDESSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFKEASQVQPSKEETSEQKALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHENVELQRQQLMLQQQLDRLRHYEAKAYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHNHHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLPTAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLGVELPADAAQAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTEQPSHNHAGDHLNCCMGKFEVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0D2H9-1", "uniprot_id": "GOG8D_HUMAN", "id": "Q0D2H9-1", "name": "Putative golgin subfamily A member 8D", "aln": "---------------------------------------------------------------------------------------------------------MEWKLEQSMREQALLKAQLTQLKESLKEVQLERDEYAEHLKGERARWQQRMRKMSQEVCSLKKEKKHDKYRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER--------------------------VAGALQAQVEYNQRIS-------LLNEGQKERLREQEERLQEQQERLPEQEERLQQLAEPQNSFKELN----------------------------------NENKSVLQLEQQVKELQEKLG---------------------------------KERLEAASQQKQQLTAQLS-------------------------------------LMALPGEGHGGEHLDSEGEEAPRPMPSVPEDLESREAMSGFMDHLEEKADLSELVEKEELGFFQYYRERCHQKVYHPITKPGGSAKDAAPGGG---------------HHQAGPGQGGDEGEAAGAAGDGVAAGGDYKGHSKFLVTAQNPAHEPSPGAPAPQELGAAHKHGDLCEVS-LTDSVEPVQG-------EAREGSPHDNPTAQPIVQDHQEHPGLGSNCCVPFFCWAWLPRRRR----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *:* *:*:**::: : :* :** :* . :: * :* :: .:: .: :::::: :* :* :::*:* :. *. *: . :.*:::*.: * . :*:* *:*:* *.:.::: : :: :*.*. .:.: :** :*:* **::* : :*... *:::: *:*:: ***:* . ::.:* * :. :: * .* .....: .: :. : : : * :: :: :.* : : : .:*: :::*. :::*. :.:: .. .: *..* : . . :*. * :..*...: .... *. :.*.: . :. :* . *:: * * * : .*. :::** :*. :. : : ..:. : ::* :.* :*. .: * :*. ", "identical_positions": 74, "similar_positions": 195, "identity": "9.31%" }, { "cls_id": "homologset.agr.HGNC:32378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "MPDDTQDAKAQKLAAARKKLKEYQQRASNNNGQPGAEEPVAATTQSHSSTVSISSNLSERSDSEINVNGGGAGGTQPPEQSALPTAASYFAQNESEHNGGLADASSLQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQNQLRLEQLQQHCQDQQSTGEQQRQQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDESSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNISLQAQFK--EASQVQPSKEETSEQKALKDELAVLKEQIEN---FEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKN-QLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLSHENVELQRQQLMLQQQLDRLRHYEAKAYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDNDHDHSHEHNHHNAGDHGHPHDHPHDHTHDHSHSHPHDHQHDHPHDHGQNHAHRQAAETLPTAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLGVELPADAAQAKQPEAAAGSEHTPGEGENSQQIINKIQDIISEIKENTEQPSHNHAGDHLNCCMGKFEVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0DX52-1", "uniprot_id": "GOG8F_HUMAN", "id": "P0DX52-1", "name": "Golgin subfamily A member 8F", "aln": "---MAEETRQSKLAAAKRKLKEYWQRNS-----PGVPAGAKRNRKTNGSIHETATSGGCHSPGDSATGIHGESPTSSATLKDLESPCQELAVVPDSRS----------------VKVSQLKNTIKSLKQQNKQVEHQLEEEKKANNEKQKAERELEVQIQRLN-------IQKGKLNTDLYHTKRSLRYFEEESKDLAVRLQHSLQRKGELERALS--AVTATQKKKAERQFSSRSKARMEWKLEQSMREQALLKAQLTQLKESLKEVQLERD-------EYAEHLKGERARWQQRMRKMSQEVCSLKKEKKHDKYRVEKLERSLSKLKHQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVEYNQRISLLNEGQKERLREQEERLQEQQERLPEQEERLQQLAEPQNSFKELNNENKSVLQLEQQVKELQEKLGKERLEAASQQKQQLTAQLSLMALPGEGD--GGGHLDSEGEEAPRPIPSIPQDLESREAMSGFMDHLEEKADLSELVEKEELGFFQYYRERCHQKVYHPITKPGGSAKDAAPGGG---------------HHQAGPGQGGDEGEAAGAAGDGVAAGGDYKGHSKFLVTAQNPAHEPSPGAPAPQELGAAHKHGDLCEVS-LTDSVEPVQG-------EAREGSPHDNPTAQPIVQDHQEHPGLGSNCCVPFFCWAWLPRRRR----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::: .*****::***** ** * **. . . :::.* . ::. . :* .: .. * . *... . * :... :* ..:. .: :**: :..:: :: * :*** : ::::* .:*: : * : * .:*:::* ::: .:: :.. ::* .:*::* *:: **:: ** : : **:*..*.. : ::*. :: * : : *: :*: : :: ::: :*.:* .** *: ::* ::*: : **::.::: :* ***.:.* *: *.. * .. * :* *: . *: *:* :.: .. : :::.*:::** ::. * * *::*::* * . .:* :* .:. : :: : :*: .*: *** : : :.: :.: .. .: .: :. : : : : :: :: :.* : : : .:*: :::*. :::*. :.:: .. .: *..* : . . :*. * :..*...: .... *. :.*.: . :. :* . *:: * * * : .*. :::** :*. :. : : ..:. : ::* :.* :*. .: * :*. ", "identical_positions": 113, "similar_positions": 280, "identity": "14.11%" }, { "cls_id": "homologset.agr.HGNC:3238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08154-1", "uniprot_id": "EGR1_RAT", "id": "P08154-1", "name": "Early growth response protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNYPKLEEMMLLSNGAP-------------------------------------------------QFLGAAGTPEGSGGNNSSSSSSSSSGGGGGGGSNSGSS--AFNPQGEPSEQPYEHLTTESFSDIALNNEKALVETSYPSQTTRLPPITYT-----GRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPTS-----------SSSAPSPAASSSSSASQSPPLSCAVPSNDSSPIYSAAP-------------------------------------------------------------TFPTPNTDIFPEPQSQAFPGSAG--------------------------------------------------------------------------------------------------------------------------TALQYPPPAYPATKGG--------------------------------------------------------------------------FQVPMIPDYLFPQQQGDLS-----------------------------------------------------------------LGTPDQKPFQGLENRTQQPSLTPLSTIKAFATQSGSQDLKALNNTYQSQLIKP----------------------------------------------------------------------------------------SRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK--SVVASSAASSLSSYPSPVATSYPS--------PATTSFPSPVPTSYSSPGSSTYPSPA----HSGFPSPSVATTYASVPPAFPAQVS-TFQSAGVSNSFS--TSTGLSDMTATFSPRTIEIC---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08046-1", "uniprot_id": "EGR1_MOUSE", "id": "P08046-1", "name": "Early growth response protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAP-------------------------------------------------QFLGAAGTPEGSGGN---SSSSTSSGGGGGGGSNSGSS--AFNPQGEPSEQPYEHLTTESFSDIALNNEKAMVETSYPSQTTRLPPITYT-----GRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPTS-----------SSSAPSPAASSSSSASQSPPLSCAVPSNDSSPIYSAAP-------------------------------------------------------------TFPTPNTDIFPEPQSQAFPGSAG--------------------------------------------------------------------------------------------------------------------------TALQYPPPAYPATKGG--------------------------------------------------------------------------FQVPMIPDYLFPQQQGDLS-----------------------------------------------------------------LGTPDQKPFQGLENRTQQPSLTPLSTIKAFATQSGSQDLKALNTTYQSQLIKP----------------------------------------------------------------------------------------SRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK--SVVASPAASSLSSYPSPVATSYPS--------PATTSFPSPVPTSYSSPGSSTYPSPA----HSGFPSPSVATTFASVPPAFPTQVS-SFPSAGVSSSFS--TSTGLSDMTATFSPRTIEIC---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18146-1", "uniprot_id": "EGR1_HUMAN", "id": "P18146-1", "name": "Early growth response protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAP-------------------------------------------------QFLGAAGAPEGSGSN--SSSSSSGGGGGGGGGSNSSSSSSTFNPQADTGEQPYEHLTAESFPDISLNNEKVLVETSYPSQTTRLPPITYT-----GRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPAS-----------SSSAPSPAASS-ASASQSPPLSCAVPSNDSSPIYSAAP-------------------------------------------------------------TFPTPNTDIFPEPQSQAFPGSAG--------------------------------------------------------------------------------------------------------------------------TALQYPPPAYPAAKGG--------------------------------------------------------------------------FQVPMIPDYLFPQQQGDLG-----------------------------------------------------------------LGTPDQKPFQGLESRTQQPSLTPLSTIKAFATQSGSQDLKALNTSYQSQLIKP----------------------------------------------------------------------------------------SRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK--SVVASSATSSLSSYPSPVATSYPSPVTTSYPSPATTSYPSPVPTSFSSPGSSTYPSPV----HSGFPSPSVATTYSSVPPAFPAQVS-SFPSSAVTNSFS--ASTGLSDMTATFSPRTIEIC---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26632-1", "uniprot_id": "EGR1_DANRE", "id": "P26632-1", "name": "Early growth response protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKTEMLLP-ALQISDPL-SFPHSP-TDNYPKLEEMIMLNSAGT-------------------------------------------------PFLNAT-APEG-----------------------------AVFGSGEPGEQ-FDHLAGDTLSEISM--EKPLSDQTYS--TQRLPPISYT-----GRFTLEPATNCSNSLWAEPLFSLVSGLVGINPPPASIPSSTSQATHPSSSSTSSIPSSSSSSTSSASLSCSVHQSEPNPIYSAAP-------------------------------------------------------------TYSSASPDIFPES-GPNFSTTVG--------------------------------------------------------------------------------------------------------------------------TSLQYSSSTYPSAKTCNP-----------------------------------------------------------------------SFSVPMIPDYLFTQQQSEIS-----------------------------------------------------------------LVPPDQKPIQTQAG--QQPALTPLHTIKAFATQTGSQDLKSV---YQSQLIKP----------------------------------------------------------------------------------------SRMRKYPNRPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEKGATAAVQSSVSNISISASSPVSSYPS---------PITSYPSPVS-SFPSPVNSCYSSPV----HTSYPSPSIATTYPSATSTFQTQVATSFPTSVASNIYSSPVTTPLPDMQSALSPRTADIC---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGW2-1", "uniprot_id": "A0A0B4KGW2_DROME", "id": "A0A0B4KGW2-1", "name": "", "aln": "MLLTMRRQNELIVGSQQHPSATSSASSSAGATSSPGLSGQNLNLVAGAGAATNSTSANSQDSLNTPTTPLLGLSRNPLQFAPPPAPPIAVPNPAASGPTFGYYQTVNAAPPIHHSPAATSEVSTAPQPPVELDEYVDILQVQQLLLDSSAAAAAAANNPPTTEQSVQQPQQNTVVQPHPHQQQQQQQQQQQPQQQQQQPQQILAKPRPRINLQKATEYAAQLAQAESSSPGSRRVLLDYPSPYLYGNPYHHHTPPGEDLVALWFGSNGTGGVAPGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTAAQSSGSPSTATYLSPAQFGGSHHGGASTSSNSLNSSSTASSSSTSSSLLHYTTASAAAAAAAAAAASANNSVLRARNQTATPTQGGSPGHVAVQPSATASSGRSSASHLSLLN-TSGQHSPTSSAVEQVEAHKQLIEALPGDLNTPVTTSSDIPSFFGPTTVVEPPPITGSIESEDLSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEESSNNSCNMYPQHNNNNNNNNNTTSSSTTTTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNTSSSNSNCHHSHQQQQQQQQQQHMSSPQQQYQQHQILHQQQQLPNHHHHHHHHHHHHSQLQQLQQQQQQQQQQQQHQQQPLHQQQQLQHQQQQQHHQQHYQQHAIQHQQSQQQASKISYRGIFTTTGNAMNAAAAAAAAAAQQQHQQQQQHQQQLPSPQLGVLAGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPPSYAGASAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSTVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEKVRGEQQQQQQQQQQQQQQQQQQQLQQQQEQHHLSLQQHQQYQQHHLLHSADLAIVTSSASMXRLENSASSVDQAQTPTPTPAPAATQKVSLALALDLDESAFPFELTSDYGTLSPLTSPRQFNYVWVGQDSSQPFFYKDNVSVQEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * *::: * .. * :: : .. ..... . * : . : . . . * . : * *:.:::*:..... . . :**:. . *.:* .: .. :. ::::. ..: .. :. ** .: * .:... :. . . .* ::*: . ::* *.:* : *** : * ...:: :* .** * : :* * . : *. *: * : *********** **********.*******************************.********************:*:***********:***:*:*::*: ** . . .. . . . .: . .. .:. ::. . . *. .: ..: :*: :: . :. :: : . *** : ", "identical_positions": 131, "similar_positions": 147, "identity": "10.3%" }, { "cls_id": "homologset.agr.HGNC:32387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84082-1", "uniprot_id": "ARF2_RAT", "id": "P84082-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "I3L3L1-1", "uniprot_id": "AL17B_HUMAN", "id": "I3L3L1-1", "name": "Putative ADP-ribosylation factor-like protein 17B", "aln": "MGNIFEKLFKSLLGKKKMRILILSLDTAGKTTILYKLKLGETVPAVPTVGFCVETVEYKNNTFAVWDVGSHFKIRPLWQHFFQNTKGARSPGSTHQGSLASGVLPIKCSHVEFGMWKGGRSHPFLPHSSR-CAGSGGQLDSILPHQSPAWGPWGCKDLSSGFPSFLTSSILWKSAVLLTPKA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:********:***:****::.**:************** *.::**:** ******** :*:*****.: ******:*:****:* .::: . .. . : . :.. *: :.. * ...:: . * :* * : .: . * ..: * * * . * ", "identical_positions": 75, "similar_positions": 50, "identity": "41.21%" }, { "cls_id": "homologset.agr.HGNC:32388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4K5-1", "uniprot_id": "D4A4K5_RAT", "id": "D4A4K5-1", "name": "", "aln": "MESMSELQNPLLPRSPTHLHRP-YPYPEAPPGWSCQEKLYSYLLGGAGPAQ------------------AHQLLDPGSLQLAVEAWYRPSCLLGRDKV----KEPKAGSCETSFTEAREPLVGPAEQRSEPGQA----EEDVTIHTVSYGVQEELQGQEDSQEEE-SDGTSTESECEDAFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLAILSIAVGAGLYVAVVVALAAYMSQNGHG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3USQ7-1", "uniprot_id": "SYN1L_MOUSE", "id": "Q3USQ7-1", "name": "Synapse differentiation-inducing gene protein 1-like", "aln": "MESLSELQNPLLPRSPTHLHRP-YPYPEAPPGWSCQEQLYSFLLGGAGPAR------------------AHQLLDPGSLQLAVEAWYRPSCLLGRDKV----KEPKAGSCETSFTEAREPLAGPAEEGSEPGQA----AEDVTIHTVSYGVQEELQGQEDSQEEE-SDGTSSESECEDAFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLSIAVGAGLYVAVVVALAAYMSQNGHG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NDD5-1", "uniprot_id": "SYN1L_HUMAN", "id": "A6NDD5-1", "name": "Synapse differentiation-inducing gene protein 1-like", "aln": "MESLSELQNPLLPRSPAHLHGP-YPYPETPPSWSCQEKLYSYLLGGAGPAG------------------AHQLLDPGSLQLAVEAWYRPSCLLGRDKV----KEPRAGSCETSFTEDREPQEGPPEQPTGPGQA----AENVTIQTVSYGVQEELRDQEDDQEEEESDATSTESESEDNFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLAIAVGAGLYVAVVVALAAYMSQNGHG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZE2-1", "uniprot_id": "SYN1L_DANRE", "id": "Q5TZE2-1", "name": "Synapse differentiation-inducing gene protein 1-like", "aln": "MESLSELQNPLLDKNSKHMVMADYGYGGDFHSNQYQENIINYFVTGGGGGGGGGGGGGGVAVTGGNGKAKSQLLDATSLHLAVEAFYKPNFILYKDDVSGKGKDYKNECCETTFMEKKDKEVVVETPSTEDPQAKLLDENDVKIQTVSYEVEEE-------EYVEYETDCSSDSESEDNFIVIPPRDHLGLAIFSMLCCFWPLGIAAFYFSQGTSKAVTKGDFPLASIASRRALFLAALSITIGTGVYVGVVVALIAYLSKPGHI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:******** :.. *: . * * . . **:: .::: *.* . ****. **:*****:*:*. :* :*.* *: : .***:* * :: : ** ::*.*:**** *:** : * . *::**.** *:.:********::************************::**** *** :******** *:*::*:*:**.***** **:*: ** ", "identical_positions": 121, "similar_positions": 57, "identity": "45.66%" }, { "cls_id": "homologset.agr.HGNC:32389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JZV9-1", "uniprot_id": "DHRS6_MOUSE", "id": "Q8JZV9-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "MGRLDGKVIVLTAAAQGIGRASALAFAREGAKVIATDINESKLQELESYRGIQTRVLDVTKKRQIDQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDNPKEALKTFLNRQKTGRFASAEEVALLCVYLASDESAYVTGNPVIIDGGWSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1J4-1", "uniprot_id": "DHRS6_RAT", "id": "D4A1J4-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "MGRLEGKVIVLTAAAQGIGRASALAFAREGAKVIATDINEAKLQELENYPGIQTRVLDVTKKRQIDQFASEIEKIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDDPKEALKAFLNRQKTGRFASAEEVALLCVYLASDESAYVTGTPVVIDGGWSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BUT1-1", "uniprot_id": "DHRS6_HUMAN", "id": "Q9BUT1-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q561X9-1", "uniprot_id": "DHRS6_DANRE", "id": "Q561X9-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "MGRLDGKVIVLSAAAQGIGKASAIAFAKEGAQVTATDINGEKLKELDGIPGIKTKVVDVTKKDQVDALAKDFDHVDVLFNIAGFVHHGSILDCEESDWDFTMNVNVRSMYLMIKAFLPKMLARKSGNIINMASVASSIKGVVNRCVYSTSKAAVIGLTKSVAADFLEQGIRCNCICPGTVDTPSLRERIQARPDPEQAFKDFMARQRTGRLCTAEEVAHLCVYLASDESTFVTGTEVIIDGGWRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:****:*:*******:*:*:***:***:* ***** **:**: **:*:*:***** *:* :*.:.:::*****:*******::*****.****:**:*****:************:********:*****:*** ******::***************::*******:**********:****** :*::* : *: **:***:.:***:* **********::***. *:***** *", "identical_positions": 178, "similar_positions": 51, "identity": "72.65%" }, { "cls_id": "homologset.agr.HGNC:3239", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51774-1", "uniprot_id": "EGR2_RAT", "id": "P51774-1", "name": "E3 SUMO-protein ligase EGR2", "aln": "-MMTAKAVDKIPVTLSGFMHQLPDSLYPVEDLAAP---SVTIFPNGELGGPFDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPISAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTPPASTTASSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLYQDPSAFLSPPPTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFP-SPCQRDPHGAAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGGEGPRLPGS---GSAAVTATPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSSSASAQSSASGPGGSQAGGSLCG--NSAIGG-PLASCTSRTRTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08152-1", "uniprot_id": "EGR2_MOUSE", "id": "P08152-1", "name": "E3 SUMO-protein ligase EGR2", "aln": "-MMTAKAVDKIPVTLSGFMHQLPDSLYPVEDLAAS---SVTIFPNGELGGPFDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPISAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTPPASTTASSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLYQDPSAFLSPPSTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFP-SPCQRDPHGAAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPGAGVTGPGASGGGEGPRLPGS---GSAAVTATPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSAPPSAQSSASGPGGSQAGGSLCG--NSAIGG-PLASCTSRTRTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11161-1", "uniprot_id": "EGR2_HUMAN", "id": "P11161-1", "name": "E3 SUMO-protein ligase EGR2", "aln": "-MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAAT---SVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFP-SQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05159-1", "uniprot_id": "EGR2B_DANRE", "id": "Q05159-1", "name": "Early growth response protein 2b", "aln": "--MTAKTLEKAPVSLGGFVHPLADSIYSVDELGTTLPASVTIYN--DLGGHYEQIN--AGDGLINGDMSTEKRALDLAYSSTFAQPAGPRNQTFTYMGKFSIDSQYPGN-WNPEGVINIVSAGILG-MTQPSS-ASSSPASSVSPSHFSSTLS--CTMAQNQADMEHIYSPPPP---YSGCG-EVYQDPSAFLS----TSTCPISY-PPPSYSSPKPNADSGLFPIIPDYAGFFQ-PPCQRDMQ--SMPDRKPFSCPLDSFKLPPPLTPLNTIRNFTLGGP-----------GPDGPRLPTA------------YTPQNLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERKSSSSSTGVSSSERG-------VATSICS--------------SSSNQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F266-1", "uniprot_id": "E7F266_DANRE", "id": "E7F266-1", "name": "", "aln": "MTATASTGDKMSASLTDFMRCLPSHVYGLDEIPPC---APTGFPHVDAGVCSDHYSEASAGGLSSDSFGVEKRDLDLPDPGKFSPHSAP----VAYTGKISIDAQ---GSWSQEGIINFISAGVQDRSTSPGSFSTGSPAGPPSD---------CSKIVQNLPNMEHMYTGPPP----YTCSAEGYQDPSVYLS----TTTCPITY-APPSYSAPKSTIDGALFSIIPDYGGFYQNSSCQRDNMA-VFQDIKPFSCSLESIRVPPPLTPLNTIRNFTLACP------------VDGSRPPLDG-----------TNPQNVPLRPILRPRKYPNRPCKTPVHERPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRKLSVGPHSSSAGGN------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.: :* ..:* .*:: *.. :* :::: . : * : : * :: . :..*: . .: *** ***. ...*: :.* .:* **:***.* **:**::***: * *.* ::.*.. . * ..: *. .:::*:*: *** * : *****.:** :::..::* .****.:**. * .*:.:**** **: . **** * ***.*.*:::::*******.*******. * :*.* * .*:::***************.*****************************:****************.********************:**:***********:****** *:*:** * . .: ", "identical_positions": 199, "similar_positions": 108, "identity": "41.37%" }, { "cls_id": "homologset.agr.HGNC:32390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GV27-1", "uniprot_id": "TM225_RAT", "id": "Q6GV27-1", "name": "Transmembrane protein 225", "aln": "MMRIPNRSIQAANIFFSSGAILLLIAGLIMENWVELIPKVRKDKVTHSPWLGCCPPFWPEESLEAIRRMMMMSLNISIYLNLIIGLQFTYMISQNKCVHLLIGFLSFFTGCLLFYAIIVYHHKLNKGQYVYFVNYKTKWIVFTIYLTIALFLTCGIFSFIQC---TNRCACMKFCVPHTESSSKAMTQNTIQVISLPPRSEMPRSIVHMHSDMPGKEGSISKPHLQSRRVTWAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9S2-1", "uniprot_id": "TM225_MOUSE", "id": "Q9D9S2-1", "name": "Transmembrane protein 225", "aln": "MMHIPNRSIQAANIFFSSGAILLLIVGLIMEDWVELIPKVRKDKTTHSPWLGCCPPFWPEESLEVVRRIMRMTLNISIYLNLIIGLQFSYMISQNKCVHLLVGFLSFFAGCLLFYAIIVYHHKLNKGQYVYFVNYKTKWIAFTVYLTIALFLTCGIFCFIQS---TNRCECMKFCIPHTESKSQEMIPSTIEVVSLPPRCAMPRSIVHVHS-VTSKDGSLNRPHTQARRVTWAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6GV28-1", "uniprot_id": "TM225_HUMAN", "id": "Q6GV28-1", "name": "Transmembrane protein 225", "aln": "MVHVSNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPEDDLKVVRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYHNKLKQGQSMHFSSYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNECKE---SENSIEDISLPECTAMPRSIVRAHT-----VNSLNK-KVQTRHVTWAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::.*****. **:*** *::*:: *: ::.*****.: .: * .****: ***.:***:.*:.:* :* :*.:*: ****:*::*:*:*.*** ::*: :****:* *::*:*:**:**::** ::* .*: .** :* **.: :: .**::.:::. *. * *::: ...*... .:*: :*** ******: *: .*:.: : *:*:*****", "identical_positions": 93, "similar_positions": 91, "identity": "39.74%" }, { "cls_id": "homologset.agr.HGNC:32393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C581-1", "uniprot_id": "TMM91_MOUSE", "id": "Q8C581-1", "name": "Transmembrane protein 91", "aln": "MDNSSIQELQQPLLPSITCDLLAPRSEKPELGTPFPETAFAESPRGWQLLLPPLPSVSAGLGEPETPDFEDTLSSDSDSDDDGGDRLSPLLPHDHLGLAVFSVLCCFWPVGIAAFCLAHKTNKAWAKGDVQGAGAASRRAFLLGVLAVGLGLCTYAAALVTLAAYLASRDPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LKI8-1", "uniprot_id": "A0ABK0LKI8_RAT", "id": "A0ABK0LKI8-1", "name": "", "aln": "MDNSSIQELQQPLLPSVTWDLLASKSEKPELGTLFPETAFADSPRGWQLLLPPLPSVSAGLGEPETPDLEDTSSSDSDSDDDGGDRLSPLLPHDHLGLAVFSVLCCFWPVGIAAFCLAHKTSKAWAKGDVQGAGAASRRAFLLGVLAVGLGLCTYAAALVTLAAYLASRDPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZNR0-1", "uniprot_id": "TMM91_HUMAN", "id": "Q6ZNR0-1", "name": "Transmembrane protein 91", "aln": "MDSPSLRELQQPLLEGTECETPAQKPGRHELGSPLREIAFAESLRGLQFLSPPLPSVSAGLGEPRPPDVEDMSSSDSDSDWDGGSRLSPFLPHDHLGLAVFSMLCCFWPVGIAAFCLAQKTNKAWAKGDIQGAGAASRRAFLLGVLAVGLGVCTYAAALVTLAAYLASRDPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..*::******* . : * :. : ***: : * ***:* ** *:* *************..**.** ******* ***.****:************:***************:**.*******:*********************:********************", "identical_positions": 131, "similar_positions": 23, "identity": "76.16%" }, { "cls_id": "homologset.agr.HGNC:32394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZP11-1", "uniprot_id": "A0A8I5ZP11_RAT", "id": "A0A8I5ZP11-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQTEGNPSEDGTTVSPTAGNLATPGSQGTAEEVAEGTVGTNDK------------------------------------------------------------------------------------------EEPPDGAEHLCKAASEGGISGGCQVEASILEELKTDSQGEARGKEE-AKADLAEEKGGKEDTTVSSQEDTGKKEETKPEPSEVTEKEEAVLPLEKQKVDEKETNLESKEKSDVNDKAEPES-----------------------------------KEDAG----------AEVTVKEAETESQKKADVKDQAEPQLQEVDGKE-----------------------------------------------------ARSDTKELVEPGSP---------------------------------------------------------TEEQEEQGKENESEERAAVIPSSPEDWPESPTDEGTSLSPDGLGPESTASGETSAS--ASESSPSEVPESPTEPLPSEKKKERAPERRVSAPTRPRGPRAQNRKAIMDKFGGAASGPTALFRNTKAAGAAIGG------------------------------------------------------VKNMLLEWCRAMTRNYEHVDIQNFSSSWSSGMAFCALIHKFFPDAFDYAELDPTKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LM3-1", "uniprot_id": "SMTL1_MOUSE", "id": "Q99LM3-1", "name": "Smoothelin-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQTEGNSSEDGTTVSPTAGNLETPGSQGIAEEVAEGTVGTSDK------------------------------------------------------------------------------------------EGPSDWAEHLCKAASKSGESGGSPGEASILDELKTDLQGEARGKDE-AQGDLAEEKVGKEDTTAASQEDTGKKEETKPEPNEVREKEEAMLASEKQKVDEKETNLESKEKSDVNDKAKPEP-----------------------------------KEDAG----------AEVTVNEAETESQEEADVKDQAKPELPEVDGKE-----------------------------------------------------TGSDTKELVEPESP---------------------------------------------------------TEEQE-QGKENESEERAAVIPSSPEEWPESPTDEGPSLSPDGLAPES--TGETSPS--ASESSPSEVPGSPTEPQPSEKKKDRAPERRVSAPSRPRGPRAQNRKAIMDKFGGAASGPTALFRNTKAAGAAIGG------------------------------------------------------VKNMLLEWCRAMTRNYEHVDIQNFSSSWSSGMAFCALIHKFFPEAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MU46-1", "uniprot_id": "SMTL1_HUMAN", "id": "A8MU46-1", "name": "Smoothelin-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQKEGKLSEDGTTVSPAADNPEMSGG-GAPAEETKGTAGKAIN------------------------------------------------------------------------------------------EGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKED-AEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKE-STLASEKQKAEEKEAKPESGQKADANDRDKPEPKA----------------------TVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQK-AVVEDEAKAEPKEPDGKEEAKHGAKE----------------------------------------EADAKEEAEDAEEAEPGSP---------------------------------------------------------SEEQE-QDVEKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPS--ASESSPSDVPQSPPESPSSGEKKEKAPERRVSAPARPRGPRAQNRKAIVDKFGGAASGPTALFRNTKAAGAAIGG------------------------------------------------------VKNMLLEWCRAMTKKYEHVDIQNFSSSWSSGMAFCALIHKFFPDAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLDVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PDW8-1", "uniprot_id": "M9PDW8_DROME", "id": "M9PDW8-1", "name": "Calponin-homology (CH) domain-containing protein", "aln": "MEVECDLGDIQNEELLRKMWQQSEDSERKRQIRSHLYKLRESRLCNLYRHETDPMSEPNGNGHGNVNTLAGYAGKDPLATSHGDALLDQNFQSLKSKEVRDSTSPTHELRFHSMTLSQPNTTGWDVQTSSEVSPDGRAYRTETLAKTDGVEKLNGGGLAEFKGRNEQRSSASHQGDDKNFVKQASDSSKTQLQETVVFGDETSGRTEMKMSSTSTSSSSKVVSSSSTVEYGDEPRYLLDNQEKPHKQHQTREWEQDQRRQEQRIQEQRQEQQIRQEQLQRQEEFQRQEQIQRQEQIQRQEQVQRQQERFTESREQSNSTRNVQTQQHYEENKRYVDMDKASPEYQRHVQHLMEQPGEIISNTVEYPKPNVKMITTVKRLPDGTIVKNKRYETEQLTPSQSHTTHKQTNNQTHNQTRNQVHNQRREQDEQDSQTRDVVDNVEQKHVTESQSFSSVKKSSRRFSTETTSETVEEYDDRDQPTSRVVQKAPTPSYAPPSHSPRQSPAKDFSTHGFPSVRPNKATQEYPSQRPGIAGEEVVVVRSEKSRQVKQQTSSQRTIETEVVGDDYQEPQRSPQKLREAPTPSWEQPATRRQPVEEDFSTHGFPSVRTTTTSTRPDQPDGEVLHTSKTVSRNQSANRKTNTERIIETQVEHPNAPSHSTPRSGSPRRSQPRDDYASSPRGPAGKPSQSRPSNTGGSTTTKTTTTSEPLTRRQLQKEREVDAAHRAFAASLRSSSPADSTTSVGSHHQTPRSSVSSNRTFRREMREGSHDSQAPSESSRISSTTVTRHTTGGNVTSNTIKTKTTKPVKTASEPRSPTPKAGGSVTTTTTTITTKSSPSPAPASPTTAAPPTSAPASSAPPDNKLSQYTYTTTKPGDIFSLPPTTPPTINNEPTLTTTRNTTTTTTTTTTATSDNLQNHPKKSAIEPATDTDSQPIRKVKLSANEAKVVEEAPCVRRQYYQLGNEGENPETPESSGTPANKKPHQMRRPHDEPEPQLRRSSKSPSVEPRQVQRETTFEGRRVSQDREISIDELILIEETSGAPGSPKIPSPRAQSPGKPATRSQSPEKPQPRATPRQSPEKEQPAFKQTHEVYTPSQPEKQFPRARSPEKTPGWTQPQVSPRQSPEKQLPRAQSPEKVPAVRQPSVSPRQSPEKQIPDPKTRDQGPGLPRISPRQSPEKQLPKDVPQKSRQSPEKDLTNQQRREEEIFRSTITTTQKRTTNNLNEEFITNERDNQNQPISEKKPQIPANAEPNTKPSETIESPDGGFPSKTTEVEAQPEVKESPTYRKKGLTRRETFEDRCRQILGMEEDGDTQGTYTERPNNEQEDVNVSHTTIETIQVKIEDCPNDDEDDKPRRVTETYVVRTQPKIKVEEELFVDVTEAEDVEILVNPSKKSPKEEDSPKYPKGPETPKSPRNDQRIPSIPKKGQSPVQFKTEETPRYPQEQERYPKEPETSQYPKESPRNPKEDAETININEETTIVITKEGSKSPSPRWSPSPERRVPKSQQPPSPTASPSVSPVSGRKIPNEVESNFVTEKIIDCRGKTVVEKISQRPRTPSPTTPKKNTKPSQKIPERVPETESEPEKDSESETKKTTSVSVTKTETERRNSRTTKTKQPLPLKEPQSKVPAGKSPRKDSLTGRKRDSLVEETRITTTTTTTRQGRKPSDTNGSPSIKDRLRSSPRKQKTSPQQTRTPTPAQTRNPEDDVDGDSSSPDASPTRVGNERRRSSNISVHTEIIIDHMAPKSPKTERRSQGGTGNVPSPIRKLPVTERKESAPVPRVTRRDKAEKVTRSTSENIIKMSGTKPHPEMSSLKPGGDRSRPSKCCTTKTINLSEQRINTATDIEGVIIDIQQAKSSREPSPDRIVPTPVPAELETGKPRYPDVVQEPDDEPRRKPQVTNIPIFEEESQTYVGCQISELHSSNGIEVDILDNPTVEAPKSLDYPVNTPDTDESLLSVHEKVSRFTHSAEKVKEPKVSAPFSREFDVNAKIPENDDCLLSINQKVDKFLRTAENVIRPTSLPSRPEIERPGLEEIDEELLRDDCTLSVSQKVHKFIDTAEKLAPTMPQKSPRLVANIERHISRQSEPERELDEESEPELDRDTDVEDDDQTSQLETEEEITQTVTKKETLKEFKQQTKETRETRRDSKAEPEKLQKKSPQTKVKEESARVPKYQAKVSQKVSQWEPKKQPQREPKVTQKETPLEPKKQPLSKVKDEPEKVNKREPKVPQKESQTKLKEEPERVTKKTPQKEPRKEPLRQSEDEPEFSPEEEFDDEPLPMTKTHTTAIEMKRQKDILNRPSVFGQRTPERKSSTTPSPTKLNGTRGRPSPSTNLITEEKRSYRNQVTNVSKPGTRKTTPSANSPAQSPPPKTTSISKRMEQISQQSWVVQDVDVDVEVVGPAPPSHISEKPQGKSPSPTSSRSLSRSPSRSPSRRTSTNLNTTSTNTTTTTEHPSTIKTTTPKPTSTNPSKDEPEIIPIESLTEKSITTTYTTNTTGRNVASRRNVFEPVHETHVDSEPTGRRPSYMDHTKSSLEHIRRDSLEINKSHYSRKSSMEDDSPVEPRNPNSSVKFDVPRKSSSRGADEPRKTSLKGKDEDSDLELEIEEIFDLQRLEKLLETVASYEMRRRIRAQMRLIRKNMINAGTTTTITTITTSTTPGKSSPLPKIRRDQSPAGAAEVKTKEVRTTTSRRQQQQRVEQVDSTTPIAPGKTSPHGKPPVKPRERSASPAQKRRISPPGKQSPGDRSTTTTTKVTTTSTTRGAPSKPAQGPIWADRSKVLKGHATVPQTNGSTPRKGSTSSTTSSSGKITRTMTSSSTTTSSSSTTNTRNKQREEDSITSSYGVGPTDENGLPLFGIRALKKKATPPAEEPCETKQEVTGYVIEEQFYSDNKSPPRHERKELIYSSNADELAAIKQQLQDEDDSSPPLLDARVVREFKKVESQQSLPEDARYVRRGSVKELSEKFIRKESSSSTHSTHSSIAQSLVRHEDETEDDSESNDVCSVIEAPQMRQNQSHTMSTTRSSNTRSFLNSSADQRQVTSVDDVLERMRNADNVEEPGDSSEDREARALLNKFLGASVIMQGVESMLPPTATGQRLNSQGVKTTRITNTYSKSGNSTSTTNNTSNTTNKVSSSSAPVTRTTCDIEEIWDEQVLKQLLEQASTYEERRKIRARLRELMAEREEQKNLKQAPKEEKEEEESSASEYEEIIEEVTDYSDEEEEVPPKKEEPKKEEVTKKEVTKKEVTTKQQEEIQQKAVKKVEKTETKTSQATESVSKKLAKVELASSSSSSTTDGVQVQGESLPAKATKTGATGAAGPVSSSSIGSRKSSSLSSSQVSTVVRARDKAKPEMMPVAGTGSGSESVPGSGAPNTGSRLSVPSKEDSGTESGEDLRLLAAGLRDTLQQQSGSDASEANRSLVEEVTDALSRLESSLKQGKELAVDGGQRQALLGLVARLQSGLSAPEKLAEDRKTDECQKEVETGSPEPDGDSRQSRFAKRRQRNSRHTVGVSREELADARRYMEDMLILEGKDFALSKTPSSSAVPVQLYRPNQFVAQSQQPQSVNNQPNATQALPTQNQSQLRPNTSNRRPLSGDYAVSFASYEANQNSQNSSPEGNGNSASNSQSNSNSSSNSSRFGGGKKHLMKRANTIDIPKAKAKYMADCDSDSDLEDDHGPHLGLKRAVQVSVKRRVHNAVPPFEPKTENDHKFLAFINKQSHQTGLGWSGGGGRSVSNWTHKFGNIKHTFETGAAATVTKGKPPPVPGHVPGWAKQEQLHHQQLQREQMQREQMQREQYQREQRQREQRELREQLQREQYQREQSQRDQNQRELSKREQFQREQLQREQLQREQLQREKLQREQLQREQLQREQLQREQLQREQLQREQLQREQLQRDQLQLQQQQQAAAAVQIERQRRQELERQLRLEQEARFEREERTRLEREYYEQQLQRQQVERQQQLDRQRQQQEQMERQRRQEMELRLQQQREQAAQVNNFIHAPQSVFRPIENETQPQPGIYKPIAHKSQPNPAVWKPPTQQSQPPQQSQQHLQPRSATTYSNTPSPSSTATSPIGLPWVAKPKVDNSDFRRKAHHFEERSLRDNIEQQQQPTYPNGNNGYLQRHNSLRSKAPALSEFKKRPSLPNAMDPGTAAPPRQVYQAPPPPTNISFTYADFPPVRRPQGASAHNYRSQPCLTSAVDQVEALTNPLGAPLVLTSSNPTYLPPPGSRRFDYISSPVDVDADSPPNSPTSFMTMPNPTLMTDNTDDDLDLDSDNNMLEYRAETKVMRKPRSQTAVRVADRRNAHMSDDEVYGKNSRAAKSLLYTMKQLGGGPGNASVGNSGQRRQPLTAPSSPKSGCLSPDGRPYQAPLVEPLFPQLSTFEPKRQPQFANSPMSTPPAVSMPSINYQANPTYTPPRSNQNSNSYLGETNTSYVVTYPLDDSGDEPEPESMATSVSQRLRRTSEHSNASSSLSLGSTSWTANPVHNTVPSVPLDSAMGPPVDRSTKPQVSQPVGPKMPQHVAQKQIPQQLPNQLPQQIPQQLPKQLPQQIPQQLPQQLPQQLPKQLPQQIPPQLPKQLPQQIPQPELPQQLPNNLPRHAPKLSSRSHTIQGDSGYENRPLQNRVMSQQTLNSSIITSNNHTTVQKQQKEQHINELRRKSLGNVLESSQRSTYFEQEYKSSAPPDTPDIVKSSLPKEDAPLLKKFGPPQRHHYMPNSYQSPQLNKQGNSNSTTTSSTSVRSTTVVQQQHHQQQHQQIKPSIVETPATPQPQVPPEDEIPHNIVFNNVSAFTSMSRRNHEEDSHQGTQSGSRVNRLSKCDSWNQICQLQQTAGPSPAKYNQPGSPGELRRTKSGHSLAVPKLYEAGIDKAQVSEKQRTVAAYFSGQKSPTGGQVEELRTSMTTTTSSRKSAINRTKTSEKLSAAARKSLSSLTTTSNGNVSTAGLGMVVRGGGVGGIGGGAALSRSATMPHIANLNLLDESNVEDAFEQLMMAQHKSSSSSEQRTETKSKDGGATVTTTTTKVTTRTVSGSAASKNISPLAKFKQLDKQAAAQQAQKSSPTTSTPTTPGGSAQPLFKFTDPALNARAATVKDQLLQWCKHKTQEYENVQINNFSSSWSDGLAFCALIHHFLPDAFDYTTLTKQTRRHNFELAFSVADEKAGIAPLLDVEDMVEMSRPDWKCVFVYVQSIYRRFRNCQ-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::. .: . :. :.* : . . . . : *:.. : : * . : :. . .* *.. . * :: :: : : .:. :.. ...:. * :*::.: . .* .*. . : ..*: * : :* .*. * :.. :. : : .: : :. : : *: * .: .* .. : :* ** : .. :. :..: : .:: :. .. .* .. .:*. **. * . . *: * .: :* . . .: : * *: : * :. .. *. :: .. *.:.: .*: . . ..:*:* . **: **:**: *::**:*:*:*******.*:*******:*:*:****: * .***** ****.*:: *. * **:*:***.:: ** ***:.*:*.:** : : ", "identical_positions": 97, "similar_positions": 178, "identity": "1.87%" }, { "cls_id": "homologset.agr.HGNC:32395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZW2-1", "uniprot_id": "F1LZW2_RAT", "id": "F1LZW2-1", "name": "Diacylglycerol kinase", "aln": "MDGVDSVPQGTAQPQDGEQPAESPEPPPPP-------PPPAPPPPSPPPPSPPPPAPPPFPEPSPEPVPEPALGPCPEATPEPATERDAKSTPEPALEPDSKPDPEPDPEPDSESAPEPDPEPDSEPAPEPDPEPDSEPAPEPDPEPDSEPAPEPDPEPDSEPAPEPDPEPDSERVPEPDPEPDSERAPEPDPEPDSEPAPEPDPEPDSERVPEPAPDPTLELASEPTREPTPDPAMERAPESCPEPTPESCPKMSPALHLLQVVPGEKSGRTSPVLLPLPSPKPPVTWSRIKKILKEGPLLKNCNSFKRWKLRYCLIQGQKLHFAHHPSFAHFETIDLSQVVLAESSCRNLCHGFCVITPHRKVSLVAPSRQDMEEWINIIKTVQQGEIRQIP--AAENNPFLIGMHYWYSSPNPRTQFCNVCRENIPALSRDAIICEVCKVKSHKVCALRANKDCKWNTLSITDDLLLPADEIQTMPHQWVEGNIPANSQCTVCHESCGSYHRLQDFRCLWCGSTVHGACQKRFSKECSFGSCRSLIVPPTALSDPRGDGQLVVSSEFWNLDWPLTCSCPLLIFINSKSGDHQGIIFLRKFKQYLNPSQVFDLAKGGPEAGIAMFKNFARFRVLVCGGDGSVSWVLSTIDAYGLHDRCQMAIIPLGTGNDLARVLGWGAFWSKGKSPLEILSRVEQAHVRILDRWSVMIRETPKPVP--LLKGQVGMDIPRFEAAAIKNVESATTELNKILKAKYPTEMVIATRFLCSAVQDFIDDIVKAWHQIKQNTTAVESVILKSDLMYDKLS---------------------VLLDLLAEDAVAASAERTATAYGSRSKPDGKAFVPELDHIAKAKMELAERAQKLQQSLKLILFQVEQVLDDESRQSLSVKNFASSLFLGDG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDD-SDDYDQSPRHRSRCDTLSSIPSLRSEDLDNLDLEHLHVTPETIR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FKERCVMNNYFGIGLDAKISLEFNARREEHPEQYNSRLKNKIWYGLLGSKELLQRSYRKLEERIHLECDGEAVSLPNLQGIVVLNITSYAGGVNFWGSNTATTEYEAPAIDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCREVIITIDGEGGIPVQVDGEAWIQKPGLIKIKYKNTAQMLMRDRDFENSMKTWESKHTEIQAVPAPHLDFQESQDSLSDGEYAQMQHLARRAENLISRLTDLSKVHQHVS-VLMDSVNASATILNDVFYSQDSGNEAGAASCIPIETLSRTDAVDVTFSLKGLYDDTKAFLDEN--LLR-DAKDRAMLETALDAMNMELRRILAIGWLS-------QIFYPEEQASDTY------------SLSRRFRVKFPKLGKKK-REEGGKPKSSQRFPGFLGKFWRRRNRGKQAKDDDPPTPSSSQL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6UUZ3-1", "uniprot_id": "F6UUZ3_MOUSE", "id": "F6UUZ3-1", "name": "Diacylglycerol kinase", "aln": "MDGVDSVAQGTAQPQDGEQPAESPEPPPPPPAPPPAPPPPAPPPPAPPPPAPPPPAPPPFPEPSPEPVPEPALGPCPEATPEPATETDAKSTPEPAPKPDSEPDSDPALEPDSEPAPEPDPEPDSEPAPEPDPEPDSEPAPEPDPEPDSEPAPEPDPEPDSEPAPEPDPEPDSEPAPEPDPEPDSE----PAPEPVSEPAPELVPELASEPAPEPVLEPTLELASELALEPAPDPAMERAPESWPEPTPESCLRMSPALHLLQVVPGEKSGTASPVLLPLPSPKPPITWSRIKKILKEGPLLKNCNSFRRWKLRYCLVQGQKLHFAHHPSFAHFETIDLSQVVLAESSCRNLCHGFCVITPHRKVSLVAPTRQDMEEWINIIKTVQQGEIRQIP--AAENNPFLVGMHYWYSSSNPRSHFCNVCRENIPALSRDAVTCEVCQVKSHKFCALRANKDCKWNTLSVTDDLLLPADEIQTMPHQWVEGNIPAGSQCVVCHKSCGSHHRLQDFRCLWCGSTVHGACQKRFSKECSFGSRRSSIVPPTALSDPRGDGQLVVSPDFWNLDWPLTCSCPLLIFINSKSGDHQGIIFLRKFKQYLNPSQVFDLAKGGPEAGIAMFKNFARFRVLVCGGDGSVSWVLSTIDAYGLHDRCQLAIIPLGTGNDLARVLGWGAVWSKGTSPLDILSRVEQAHVRILDRWSVMIRETPRQAP--LLKGQVAMDIPRFEAAAIKNVESATTELNKILKAKYPTEMVIATRFLCSAVEDFVEDIVKAWHQIKQNSTAVESVILKSDLMYDKLS---------------------VLIDLLAEDAVAASAERTATAYGSRSQADGKPFVPQLDHIARAKLELAERAQKLQQSLKLIIFQVEQVLDEESRQSLSVKNFTSSLFLGDG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDDDSDDYDQSPRHRSRCDILCSIPSLRNEDLDNLDLEHLHIAPETIR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FKEKCVMNNYFGIGLDAKISLEFNSRREEHPEQYNSRLKNKIWYGLLGSKELLQRSYRKLEERIHLECDGEAVSLPNLQGIVVLNITSYAGGVNFWGRNRATTEYDVPAINDGKLEVVAIFGSVQMAMSRIVNLQQHRIAQCHEVVITIDGEDGVPVQVDGEAWIQKPGLIKIKYKNVAQMLMRDRDFENSMKTWESKHTEIQAVQPPHLDFQESQDSLSDGEYAQMQHLARLAENLISRLTDLSKVHQHVS-VLMDSVNASANILNDVFYSQDSGNEAGAASCIPIETLSRTDAVDVTFSLKGLYDDTKAFLDEN--LLR-DAEDRAMLQTALDAMNTELRRILAIGWLS-------QIFFPEEQASDTR------------SLSRRFRIKFPKLGKKKQREEGEKPKSSQRFPGFLGKFWRRRNRSNRAKADDPPTPSSSQL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5KSL6-1", "uniprot_id": "DGKK_HUMAN", "id": "Q5KSL6-1", "name": "Diacylglycerol kinase kappa", "aln": "MDRGAAAAQGTAPPQDGEQPAESPEPPPPW--------PPPPPPPAPPP--APPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPAT------------------------EPASEPAPEP--------ATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEP--------------------APELTP----------------EVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIP--AAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVN-MPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTP--LLKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLS---------------------VLIDVLAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEESRQTISVKNFSSTFFLED---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNLDHLHFTPESIR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQHLARLAENLISKLNDLSKIHQHVS-VLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFSLKGLYDDTTAFLDEK--LLR-SAEDETALQSALDAMNKEFKKLSEIDWMN-------PIFVPEEKSSDTD------------SRSLRLKIKFPKLGKKK-VEEERKPKSGQSVQSFIGNLWHRRHREDEAEGDDPLTPSRSQL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BAY3-1", "uniprot_id": "A0A8M3BAY3_DANRE", "id": "A0A8M3BAY3-1", "name": "Diacylglycerol kinase", "aln": "-----------------------------------------------------------MLEHCAQLILLKGGDECSEN-PVLCTVMASKFN------------------------------PNVLYVREP---------------QESLTSPDPQVEAGDESS-DSDGEPE-------------------------------------------------ETSHKLIRKVSTS-----------------------------------------------------GQIRAKKSVKEGLLLKQTSSFQRWKRRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAETSTKNINNSFTVITPFRKLMLCAESRKEMEDWISALKSVQKWETYEAS--QFN-MEHFSGMHNWYACSHARPTFCNVCREALPGVTSHGLSCEVCKFKAHKRCAVRSTNTCKWTTLASIGNDIIEDEDGVSMPHQWLEGNLPVSAKCVVCDRNCGSVRRLQDWRCLWCKAIVHNSCKEQLGKVCPLGQCKVSIIPPTALNSIDSDG-------FWKATSP-SCSSPLLVLVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPQLGLRLFQKFETFRTLVCGGDGSVGWVLSELDKLSLHKQCQLGVLPLGTGNDLARVLGWGGLCDDDAQLLQILEKLERATTKMLDRWSVMTYEVPTKQTPAIVKDDDPSDSP---LQITQYADSVATHLTKILDSDKHSDVISSAKFLCGTVNDFVAEVGKAYERATENKEEADAMAKKCAMLNEKLD---------------------SLVKALSEDANAQLVPAGSISPDDSDTDQSRPFR--------SREQLMLRANSLKKALRQIIDQAEKVVDEQNRHTQ-VQRMSSTSSIKR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSSEDLKEAETRQNTLSPTATTPILLEK---SESFGTVLFSEESVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CTEKCVMNNYFGIGLDAKISLEFNNKRDENPKKCSSRTKNMMWYGVLGTKELVQKTYKNLEQRVQLECDGVSMSLPSLQGLAVLNIPSYAGGINFWGGTKEDNNFGAPSFDDKKLEVVAVFGSMQMAMSRVINIQHHRIAQCRQVKITILGDEGVPVQVDGEAWIQPPGIVQIVHKNRAQMLTRDRAFESTLKSWEDKRKGDSRPSRPRLNSQQSMEYLTEEECAQVQQLGLVADTLISRIREVAKTHKVVEQELAHAVNASAAVLSEAFPSKPSSPEG----------LSRSTAVDIVNSSTVLQQETKMLLEGK--LLQLESSQKEELLSTVENLSAELQKLEDIHWIC-------PSMHCSEEESSRV------------SGKSSMKLKIMPKGKKE-KERLHKQRSSSSLS---GSWDIKASVCDVDPAGN---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JQ65-1", "uniprot_id": "DGKH_DROME", "id": "A8JQ65-1", "name": "Diacylglycerol kinase eta", "aln": "------------------------------------------------------------MAHLKLDTLHVQRSPRGSRRSSPSSGRSSACSS-----------------------------------------------------GSISPVPIIPIISISHDGDESESESEIETEPAR--------------------------------------LFQRRMSTKCTNN-------------------------------------------------------------LAAIIKEGFLLKHTWSFQRWRRRYFRLKRNMLFYAKDEKCDVFDDIDLSDLCYFECGIKNVNHSFQIITPTRSLVLCAESRREMEDWLGSLKTATAPQRPRGDSFLIEQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKDIIEQADGIIMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAVACPIGPAKLSVVPPTSVHSISTDD-------AWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAIPVP----KTPKMSISTEQEAMLTGMVTSANHHLRFIVETNDTQTLIRSTRNLCDTVDDLVCRISEHHKDDEQLAVKCDILRQKLNMLLDALQEEEIGAHSGDDLIATIRSLIARSIPVTPGSNAYLLNPNISIEKTEKDQINTKERRNSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKLPTASGESTPCTSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVEVIQEIEEGANGETVYRKSRMSLTGGANIDDAGNRLSPCSDAGENTPTERKVDFLRVPIHTGEPIVDPLCDYRPHEVFERTYYMTREMDKGKEKDKEKDKPVEIDKEKDTCVEKEGSMPAEKLVHTCNLQVPGVVVTPNPQNVYSSASITIIDTDAQTTTEQSSSDDLGGEASDVLSAISNEECSVASEIFDKQDAGQTVGDIIQNMDASNFTHIDSPETSDETEAMPGESIMDDISSVLGHDITYALQDNTLTDDTTTLCSEHAGPPKPPRKKSLSALSRTQAHPRRRNSSPPRMARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLEQHRGGDNDSDYPEHEQTPTNKGANLLATTSEDELSTQTAIKIEIQDIDATVRNLNSSMKPNTILTTSTSPTKKSGHGQDVKRITFDESCKKESFDDVNPNYPQISVVVRPPTPLRGDCIKPTVSLLPVSSGGAMTVSMTCSGMLGVRAMNASEIRRHSSHAPGLAVREFDKDKDRRHSGFNPNQLTLDPEHARFLSSSPAASRRISCGSLFKPNEALPNLQTLKGSKSSLFMGSTLFGFDHLASAEKDKEEKSGKDKEKTPTDETNRKLPIINPLVRLPNWPNLANGGGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLELSLKSWQEKQRQHSISIQRDASSTASEHANSTDEVISERECYVLLN----FIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLRAYFNVLAPNEESDGRRKSRPFWVRLRSGSTAGQQAFKPPLTNTREAANNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .: : . . * . . . :. *. . : : : :*** :**: **:**: ** :: . *.:*:. *: :***: * . :*: :.* :*** *.: * * .*::**:*:. :*: : . : : . * **: *. .*****: :..:: ..: ****: * *: ** :: ***.**: .. :: : *****:***:*..: *.**...*** ****:***** : ** *: ::. * : : ::***:: . *. *. . .***:::******:**: ***:*** ***:***** . **. *: :*::* ** ***.*****.**** :* .:*.:**:.::***************. ... :**.: * * .::*****:* * . . * . *. .* *:.:. :: ::: **.:*:*:: : : : : * :: : *. : . . : . . : : : * :*:.::::: :: : * .. ::. : : : . : . . : : * : . .: : : ..:. *:**********:******:*: :*:*:* : ** :* :***:**:*:*:*:: ::**:*::***** :.**.***:.:***.*: ** **** . : *:::* *****:***:*** **::*:::******:.* *.* *: :*:*******:* **:::* :** .*** *:* :* ::* *: *: . . * . : * . :. : : ::. : *. : . : . .. : . *. *:: * * ::: :* . * . . * ::: :. *::: : : .*: .. * .* ..:: :. . . . . : ", "identical_positions": 294, "similar_positions": 326, "identity": "13.85%" }, { "cls_id": "homologset.agr.HGNC:32397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAC5-1", "uniprot_id": "D3ZAC5_RAT", "id": "D3ZAC5-1", "name": "", "aln": "MVDYYEVLGVPRQASAEAIRKAYRKLALKWHPDKNPEHKEEAERRFKQVAQAYEVLSDARKREVYDRCGEVGEVGGGGAAGSPFHDAFQYVFSFRDPAEVFREFFGGHDPFSFDFFG-DPLENFFGDRRSTRGSRSRGSVPFSTSFTEFPGFGGGFASLDTGFTSFGSPGNSGLSSFSMSCGGGAAGNYKSVSTSTEIINGKKITTKRIVENGQERVEVEEDGELKSLIINGKEQLLRIDTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35723-1", "uniprot_id": "DNJB3_MOUSE", "id": "O35723-1", "name": "DnaJ homolog subfamily B member 3", "aln": "MVDYYEVLGVPRQASAEAIRKAYRKLALKWHPDKNPEHKEEAERRFKQVAQAYEVLSDVRKREVYDRCGEVGEVGGGGAAGSPFHDAFQYVFSFRDPAEVFREFFGGHDPFSFDFFGGDPLENFFGDRRSTRGSRSRGAVPFSTSFTEFPGFGGGFASLDTGFTSFGSPGNSGLSSFSMSCGGGAAGNYKSVSTSTEIINGKKITTKRIVENGQERVEVEEDGELKSLIINGREQLLRINTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWF6-1", "uniprot_id": "DNJB3_HUMAN", "id": "Q8WWF6-1", "name": "DnaJ homolog subfamily B member 3", "aln": "MVDYYEVLDVPRQASSEAIKKAYRKLALKWHPDKNPENKEEAERRFKQVAEAYEVLSDAKKRDIYDRYGEAGAEGG-CTGGRPFEDPFEYVFSFRDPADVFREFFGGQDPFSFDLLG-NPLENILGGSEELLGKQKQ--------------------SVCTPFLCLQ---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.******:***:*****************:************:*******.:**::*** **.* ** :.* **.*.*:*********:********:******::* :****::*. .. *.:.: *: * * .: ", "identical_positions": 101, "similar_positions": 32, "identity": "41.74%" }, { "cls_id": "homologset.agr.HGNC:324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35083-1", "uniprot_id": "PLCA_MOUSE", "id": "O35083-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "aln": "MELWPGAWTALLLLLLLLLS---TLWFCSSSAKYFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHAKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLP--DRCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTR--NHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKERRFTSPGRCQVRVLPPVSTEGLTPDDVPALADSVRHSMLTIFREISTDGLGGGDCLKKP-----------------------------------------------------GGAGEARL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99943-1", "uniprot_id": "PLCA_HUMAN", "id": "Q99943-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "aln": "MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP--GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTR--NHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTS-GQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKP-----------------------------------------------------GGGG--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYJ4-1", "uniprot_id": "Q9VYJ4_DROME", "id": "Q9VYJ4-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "MITMTSFIELLGLFLLLMLP---FLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVSTLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAWLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTR--RNTGALHPFKKGAFHMAIDQQIPILPVVFSSYCTFLNDKKKILNS-GRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYKPIKKVGIPAASSASTSSTTTTTLASPGTAVTPVADAAVAAAAAVASSSSAYGQPPGYEAGAAKASLLKTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KTI0-1", "uniprot_id": "Q7KTI0_DROME", "id": "Q7KTI0-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "-MACTCEVIGLACVVALILS-------ATAKAPYQMRMFFIFFGAGLIVFLCVPFMILRPRDYRNALFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTR--NSKDSLLPFKKGSFHIALQGKSPVQPVVISKYS-FMDDEKKTFRP-GHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKEGQALSSKKQA------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33333-1", "uniprot_id": "PLSC_YEAST", "id": "P33333-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "-------MSVIGRFLYYLRS--------------VLVVLALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAK-KPYIMIANHQSTLDIFMLGRIFP--PGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNR-GCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVN------------------THNEGSSVKKMH---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : : . . : . : : *: :: * .:. : ::: ****::*: : : .. :*:.: : * * * ::** : .: . :.. . : . : :****** :: ***:*:**:* : : *: *:*.*. : : : * : * :.** . :.: : : : * . . ", "identical_positions": 35, "similar_positions": 73, "identity": "10.03%" }, { "cls_id": "homologset.agr.HGNC:3240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06889-1", "uniprot_id": "EGR3_HUMAN", "id": "Q06889-1", "name": "Early growth response protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS--------------------------------LLNQLPDNLYP-----------------------------EEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKP-----------------NPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDN------------------------------------------------------------------------------------------------------------------------------------IISLMSAGILGVPPASGALSTQTS--------------------------------------TASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYN------------------------------LYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQP--------------------------------------------------------------------------PLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGG------------------------------------------------------------------------------APSASSAPPVSLAPVVTTCA---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43301-1", "uniprot_id": "EGR3_RAT", "id": "P43301-1", "name": "Early growth response protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS--------------------------------LLNQLPDNLYP-----------------------------EEIPSALNLFSGSSDSVAHYTQMATENVMDIGLTNEKP-----------------NPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDN------------------------------------------------------------------------------------------------------------------------------------IISLMSAGILGVPPASGALSTQTT--------------------------------------TASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYN------------------------------LYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQP--------------------------------------------------------------------------PLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGG------------------------------------------------------------------------------APSASSAPTVSLAPVVTTCA---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43300-1", "uniprot_id": "EGR3_MOUSE", "id": "P43300-1", "name": "Early growth response protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS--------------------------------LLNQLPDNLYP-----------------------------EEIPSALNLFSGSSDSVAHYNQMATENVMDIGLTNEKP-----------------NPELSYSSSFQPAPGNKTVTYLGKFAFDSPSNWCQDN------------------------------------------------------------------------------------------------------------------------------------IISLMSAGILGVPPASGALSTQTS--------------------------------------TASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYN------------------------------LYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQP--------------------------------------------------------------------------PLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGG------------------------------------------------------------------------------APSASSAPTVSLAPVVTTCA---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4KGW2-1", "uniprot_id": "A0A0B4KGW2_DROME", "id": "A0A0B4KGW2-1", "name": "", "aln": "MLLTMRRQNELIVGSQQHPSATSSASSSAGATSSPGLSGQNLNLVAGAGAATNSTSANSQDSLNTPTTPLLGLSRNPLQFAPPPAPPIAVPNPAASGPTFGYYQTVNAAPPIHHSPAATSEVSTAPQPPVELDEYVDILQVQQLLLDSSAAAAAAANNPPTTEQSVQQPQQNTVVQPHPHQQQQQQQQQQQPQQQQQQPQQILAKPRPRINLQKATEYAAQLAQAESSSPGSRRVLLDYPSPYLYGNPYHHHTPPGEDLVALWFGSNGTGGVAPGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTAAQSSGSPSTATYLSPAQFGGSHHGGASTSSNSLNSSSTASSSSTSSSLLHYTTASAAAAAAAAAAASANNSVLRARNQTATPTQGGSPGHVAVQPSATASSGRSSASHLSLLNTSGQHSPTSSAVEQVEAHKQLIEALPGDLNTPVTTSSDIPSFFGPTTVVEPPPITGSIESEDLSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEESSNNSCNMYPQHNNNNNNNNNTTSSSTTTTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNTSSSNSNCHHSHQQQQQQQQQQHMSSPQQQYQQHQILHQQQQLPNHHHHHHHHHHHHSQLQQLQQQQQQQQQQQQHQQQPLHQQQQLQHQQQQQHHQQHYQQHAIQHQQSQQQASKISYRGIFTTTGNAMNAAAAAAAAAAQQQHQQQQQHQQQLPSPQLGVLAGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPPSYAGASAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSTVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEKVRGEQQQQQQQQQQQQQQQQQQQLQQQQEQHHLSLQQHQQYQQHHLLHSADLAIVTSSASMXRLENSASSVDQAQTPTPTPAPAATQKVSLALALDLDESAFPFELTSDYGTLSPLTSPRQFNYVWVGQDSSQPFFYKDNVSVQEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*::* : ..* ** *:: **.:* . *::. :::* :* : * . : *. .*: * * : . :.* .:..::*.: .. ...**.* *.: *:: . .: ....*:.* : * :*.*** .: * *.:: .: : .: . ::. * . .*. :* .* .::*: : * . :: : : * *::: ::. : : :: : ::. : ** * ... **.* *::************:****:***.*.**************:*****:*******************************:*::**********:*****:****: ** : * **:*:. .::** : .* ", "identical_positions": 147, "similar_positions": 129, "identity": "11.57%" }, { "cls_id": "homologset.agr.HGNC:32400", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32ZG2-1", "uniprot_id": "DFB30_RAT", "id": "Q32ZG2-1", "name": "Beta-defensin 30", "aln": "MG--SLQLILVLFVLLSDVPPVRSGVNMYIRQIYDTCWKLKGHCRNVCGKKEIFHIFCGTQFLCCIERKEMPVLFVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q30KN4-1", "uniprot_id": "DFB30_MOUSE", "id": "Q30KN4-1", "name": "Beta-defensin 30", "aln": "MG--SLQLTLVLFVLLSYVPPVRSGVNMYIKRIYDTCWKLKGICRNTCQKEEIYHIFCGIQSLCCLEKKEMPVLFVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q30KP9-1", "uniprot_id": "DB135_HUMAN", "id": "Q30KP9-1", "name": "Beta-defensin 135", "aln": "MATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCVNPKYLPILTGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *: * **:: ** *** *** *:**::*: :**:*:* ** * *:* ::*:*. ***:: * :*:* *", "identical_positions": 35, "similar_positions": 20, "identity": "45.45%" }, { "cls_id": "homologset.agr.HGNC:32403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0MAP6-1", "uniprot_id": "A0ABK0MAP6_RAT", "id": "A0ABK0MAP6-1", "name": "", "aln": "MGTRQTKGSLAER-ASP---GAAPGPRRERPDFWASLLLRAGDKAGRAGGGLPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDAMGAMEKLCRQLTYHLSPHSQWRRHRGLVKRKPQACLKALLSGNPPDNMVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRALLRDLTDTLKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGTGEEARE--------SQQDPIGSSVTPARGH-ESQETVIQT--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSF4-1", "uniprot_id": "LR75A_MOUSE", "id": "Q7TSF4-1", "name": "Leucine-rich repeat-containing protein 75A", "aln": "MGTRQTKGSLAER-ASP---GAAPGPRRERPDFWASLLLRAGDKAGRAGSGLPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDAMGAMEKLCRQLTYHLSPHSQWRRHRGLK-RKPQACLKALLSGNPPDNMVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRALLRDLTDTLKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGTGEEAREG------TDQQDPIGSPVTPARGQ-ESTECVIQT--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NAA5-1", "uniprot_id": "LR75A_HUMAN", "id": "Q8NAA5-1", "name": "Leucine-rich repeat-containing protein 75A", "aln": "MGTRQTKGSLAER-ASP---GAAPGPRRERPDFWASLLLRAGDKAGRAGAGMPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQWRRHRGLVKRKPQACLKAVLAGSPPDNTVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRAVLRDLTDILKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGSGEEVREGT-----VGQEDPGGGPVAPAEDHHEGKETVAAAQT------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9L3-1", "uniprot_id": "A0A8M9Q9L3_DANRE", "id": "A0A8M9Q9L3-1", "name": "", "aln": "MGAKQTKAAGQEAGASPQCTGWKRTPTKERSDILTSLMLRSGDKLRSSGT-PPPYQRRIGMIQEMMLMARQGKHDEATEMLKTLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLAKYIHCPKTEGDALGAMEKVCRQLTYHLSPHSQWRRQ-GLLKRKPQSCLKSVLSSPPSGGTLDLSGIPLGVKDMERLCAYLHHYASRIGSLELGFTELTDDAFLLLLPTLASLPRLETLALNGNRLTRAVLKELTDTLKDPDSFPSVTWIDLGNNVDIFSLPQPFLVSLRKRCPKQGNLPTILEFGESQASEPEGRVDEEDADATNRTESMGELRSEEEEEIDGEMEIEDMMEELLDFDREVQGKEDEDDSMWTLEEPRLVKDPTAKQSRDKRASKAEGEEDLQSQSSHLSCSSQSQHSSGAIEPLREDSVPDQLAGHSHNPT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::***.: * *** * * :**.*: :**:**:*** :* ***:**:**:**:: *.***:::** :*: **************************************:******.****:*****:****************: ** ****:***::*:. *... :******* :*:**: :**:: ..::.*:***** **** .* ***:*::**** ************:*::*** ****..**.********************:*****.****:******:**. .: * * .: :. * : . . :. : ", "identical_positions": 211, "similar_positions": 75, "identity": "47.63%" }, { "cls_id": "homologset.agr.HGNC:32404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M5B9-1", "uniprot_id": "F1M5B9_RAT", "id": "F1M5B9-1", "name": "", "aln": "ASVLRAMTLPYVMTPLGFGFCSPSLLLTGQVLLVVTQADPIAEWVQNPVRLTSEPWVPTKLWSLHHSDQPPKPLKVHTSQAGARAFDYQGSSAPSQVFSPPQELKDSFLSFQAVDTSTEPHPESDQFTVSYQH--------LANQMTPPRKLQENILKPKGDQNQSLAKAIVRTTKQFTKSQLQKKTVENEYRESNLNEAYSNGLPLQPQVNREEPPEPSELIEQPEYLLGAQTRDSENL------HMVQESPDRLPLLPEEHE----KEEPVQQHFASGKVVVLKRP---DMNVPSANGNEAHHSNLANVTVKPVD-----LEI---------------------------------------LVQFSEEPDEIESSLTQQEATAPNPELSEELEPSLVRQEALGESLELPEDLETSGSQLEVPALPTKPSEEVS----------------PPIEEEA---TPEPSVPRIIETPAATASHLSQDQVHHYTLPLITAK-------LTSKPFKEAKTSPVQKETSTRTLGSRMKAGHYGLEEQP-DEPSESSGEDESPE------------------------------------SPFLE-------------------------------------------------------------------------APNKAYYYHLPNITI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIQHSNPTEVTVQPLDLGFTLTPQLTPE-ELLQTMPETTTQITETPTEVVAPGLLYQKMTVPTPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QAEHSTTPVMTTG----------------------------------------ELSQT----------------------------------------------------TQDSTTQPIETTKGAVAQAPVYQEVTLATSSQNAVEYPTFPIITFQLLNLGLTK---HLEPAREAHD------------------------------------------------FTVLKETTILPLKNPQVTLPEQVH--TQHSHQSEITLLPLNPELSMSPQPTP----------------------------------------EVELSQTVQETK-----------------------------------------PLDLELALSSEP---------------------------------------------------------TTSHEITVS-PPQYHQMTLSEPS--SIQHPNLTDVTAQPMTLEFSVIPSPN----------------------------------------LNVETSPHIQETFPEAEPPPEEVTAKAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTDVCDFCLCENHTLLCVHLSPMQKLRQVPVPRPNTYKGTLTVL------------------------ILSKNHLTELHKDSFEGLLSLQVLDLSCNKIHYIERRTFESLPFLKYISLECNLLTELSFGTFQAWHGMQFLQQLILNRNPLTVVEDPFLFKLPTLKYLDLGATQVQLTTVENILMMTLELEHLILPSNMACCLCEFKVDIEVICKTIKLHCNTGCYTGWTNTTHCPTAS-IRNPEGTFMKVLLARKENTRAELTIEPERVHSDRNDPSSSGLMNEQLDFNDESDVISALNYILPYFSEGNLEDVVSTLLPFIKLFL---------------------------------------------------------------------------------------------AEIEKAERRLLSMNRAPEGTGSLRKRHFKEVRVKSLGSKQSAQTPVENSAKDRHLWRTAPRTGSPASVELQQLHLEQKPRVLVENSFPSEPLLAKDHGKELSSSL--GPALVDKAPAPKSLPEFLDRRKDLSYTIFVLESANANVKRAKGSNPNLQPEERRGNLR------------------KKKSHFQLIAKRPVAASSAVRSLVNSPAQGVLSSLGNLSYPERPFSESYTASQPSTEKPLEENQAATDNVKENILKLTVTVPAEIKSENKPREKPTTGSIVSTSS---LVPTVQQTSKPQSDFTVGSDTHAPSTEAAHPSLMSPGEQFESHLNQQLRPLIPNNDVRRLISHVIRTLKMDCSDTRVQLACAKLISRTGLLMKLLSEQQDFKLSRTDWDTDQWKTETYINESTEAQGEQKGLEPSQVR-TAPGQG--------------ASVSPISSAEMTWGSHSRSSASLITLAQP------RQR-----FPLSDGFFWIRCPLWLRDMYRPLHDTRKKNMAQDLQDKESSGEEEIFNKDVPG---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AWG4-1", "uniprot_id": "B1AWG4_MOUSE", "id": "B1AWG4-1", "name": "", "aln": "-------------------MFSPPRELKDSFLSFQAMDTSVASHPE------SDQFTVPHQHLAKQMTPPRKPLESVPKLNGD-----QNQSPQFKSISSLDQAADDQL-FEIPDPPLDSENSS-----------------ITKFIASPQSLQKELVQHR-----PLAKEVVGTTKQFAKSQLQKKTVVDEYRDPNMNEAYSKSLPLQSQANRE---GPSEKIEHPEYPLEAQTQESENL------DMVHESPEYLPVLPEEDEPSVPKENPVQHHFASGKAAALKHP---DRNAPSPKRNEARHSKLPNVTVKPED-----LEVTVMSEADKETQQTLSQQQAPGHLPESPKEVEPSSTPQDTLEQFSGGPEEIETLLTHQEAAAPNPELPEELGPSLVQQEVLSESLELPKDLEASGSQLEVPARRTKPPEEVN----------------PPTEQEARIPTPEPSMPNIIEIPAATVSHHNQDQVHHYTLPTITVQPADVEVTITSKPFKEAEISPVQEETQTP--GPPRKVGHYSLEQQP-AVSSESSGEVGSLERYLGFLTQPPEEEEEEEEEEDEESSLTQEDIPSQHPSPILEGEPSPIELQQPIRPSESPEEVGLGPENQSEVLVKPAELPEEVKSPVEQEAPLQAPESHFETIVDTPPIHEVQPAPNKAHHHHWPNVTVRPVDLELAITSEPTRETESSLAQQESSVHPSEYTEERDSFRYKQEQLAQPSKLEILIHTSEHHHLTSSPSAHHRTHHSSSPTTMVRPPDVQLTIAQNPTAEVEPPPAL--------HEVVGKPIAISDKGVNTSTHHTHPAVTPEPSEEVELLSNQEEAPVQSAEPVEYEKSSLSQQKSTDKNPELLEEGGLSSAQQETLVNPPVFPNEMIVQPSAHYEATGPPLIQTQLHPPASYNVTAKPPELTNEVETSSQQGVEPSNDQQEEVTSQYPMPPETHQDSPVYQWVLTQPAKLPEEVSSGQQGNLSPPLKHPPGVQFIPFQQELPDQHLEPPKEGFFLSPVADSVLFSPEDLEAMFRYETSVLHKPTVIHLNQAVSSMEVESLKVPTEQVEYSQVHFEYPSYTPAFPETQFSQEKSITQEADLHEDIYPFPTQHRGLYLPPDSFMGAEPSVTQHLSLSQLEDLAENVGPSLVLQLTPAQASEPPKEIVFSPTQQVVPNQLPESLNNIVTQL-LTQQIIGPTPGQIQEEYPTEHTVSFQALDLEFTITSQYTPEANHTTEPK----------RTPPPTYPQVTFSYPSEVTVQPLDLGLTISPQPTPE-ELPQAIPEITTQITEPPREVVAPAPLYQKMTVPTPGQDQVEYPIPPAISFQPLDLELTKNSEPTRETQQPTATMKTIVPSPEHLQDYISYVAEVTVQPLDLGLTISPQSAPEELPQPMPEITTQITEPPREVVAPAPLYQKMTVPTPGQDGVEYPILTAVSFQPLDQKLTISSEPTREVHHSTTPKETTVPPPKLSQVTLPREFHIQNLYLSEAAVQPVDLGLTITPQPNSEELP-QTISEITTQITEPPKELVAPLYQ--EVTVPTPGQDQAEYPTLPVASFQPLDPELTISSEPT-----------------------------------------------------RETEQPTAEVTVQSLDLELTISLQSTPEELLQTMPEITTQITEPPGEVVTPLYQEVTVSTPSLAQTEYPTSHIVSFQPLDLELTKNSEPTRETQQPTATMKTIVPSPEHLQDYISYVAEVTVQPLNLGLTISPQSAPEELPQP-------MPEITTQITEPPREVVAPAPLYQKMTIPTPGQDQDAHSTTLQPVGLELTETSDSTREAEHYTTLVMTTVSSPKYSLPEQVLLQHLNPAEVTVQALDLGLTITPQPDTEKELSQT----------------------------------------------------TQESTTQLIDPPKEAVAQAPVYQEVTLATPSQDAFENPTLPIITFRLLDP-------DPEPAREADN------------------------------------------------LATLKETTIPPPKYPPVTLPEQVH--TQHPHPSEVTFQPLDMELSMSPQPTP----------------------------------------EVELSQAEQETKTQPSYSAKEVVTPKPGYPEVTVPTPDQDKTEDQTLTAALFQPLDLELTRSSEP---------------------------------------------------------TTPHKSTVVSLPQYYQTTLSGEV--YTQHPNLTEVTDQPLNLELTVIPSPN----------------------------------------LNVETSPHIQEMLPEPERPHEEVTAKAPMFYEITPIQDQTPHLVSPKVTDQHIKVEHDIPTISS------------------------------------------------------------------------VENGLLAATYSSTALPLTHHEMVLLSEDQVQVLHGNPTQVTIHPSHPEFSLASPPATMVKRSAPVQS---------------TESSKETAAQSPVHLKETVLMIAHGQSQHLNSETTQPEVPATTHPETTQSTASPTTHSETTHSTASPTTHPDTTQSTASPTTHPETTQSTASPTTHSETTQSTTSPTTHPETTQSTASPTTHPDTTQSTASPTIHPDTTQYTTSPTTHPETTQYTDLTTMPPPSTHYEVVLSQSSQVQTQQPKPSEVTMWPSPTSQQSSTTPQSVILASPFATMLETTAQQIPSGIALEPMDLEPTITPYAGNFNTEKDLIFQMKPNVSTSTNICDLCLCENHTLLCSHLSPKRRLHQVPVLRPGTHKGTLTILNFHGNVISYIDKNVWKAYRWAEKLILSENRLTELHKESFEGLLTLQVLDLSCNKIHYIERRTFESLPFLKYINLGCNLLTELNFGTFQAWHGMQFLQQLILNHNPLTVVEDPFLFKLPTLKYLDLGATQVQLTMVENILMMMLELEHLILPSRMACCLCKFKADIEIICKTIKLRCHTGCLT---NTTHCLKAS-IGDPEGAFMKALLARKENSRAELTIEPEKSYADQTNLGSLGLMNEQLDFNDESDVISALNYILPYFSEGNLEDVVSTLLPFIKLLFSNIQNGDNSLGPFQNDTKSLTLKSVPKASKLAYKNKVNKLYFLENLLDEEINEVKEKEKTAMLVHHSGRLDPKFKRQIFEKRWEPARTGKDSLAEIEKAERQLHSMSRVPKETGSIQKRHFKDVSGKSLWSKQSVQTPVESISKDRQLG-------SPPSMELQQLGLEQKPRELVGYSFPSEPLLPKEHRGELSSSP--DLPLLDKAPTTNSLPDFIDRRKDLSYTIYVLESANANVKRAKGSNPSLQPEARHRNLR------------------KKKSHFQLIAKRP-AASSAVRSLISSSARGVFSSLGDLRYPERPFSELYVAPEPSTKKPLEENRAATDNVEENNLKQIVTTPEETTSENKPPENPTADSNVSTTSN--LISTVQQTSKPQSVFTVGADTHADLTDVAYPSLMSPGEQFESHLNQQLLPLIPNKDVRRLISHVIRTLKMDCSDTRVQMSCAKLISRTGLLMKLLSEQQDFKLSRADWDTDQWKTENYINESTETQGEQRSLEPSQLTKAVPGYGYNNKVILAISVTVIVTVLIIIFCLIEIYSHRTAKEGDEEKSSR------YKKNYYKISETQDGFFWLRCPLWLRDMYRPLHDTRKKNMAQDLQDKESSGEEEIFNKDVPREFKRRSSVKSSAEESVVEAPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2A9H6-1", "uniprot_id": "A2A9H6_MOUSE", "id": "A2A9H6-1", "name": "", "aln": "-------------------MLSPLEELTDSLLPFQDPSTLQELNPAS-------EELISHQDLTDKLIPTGKQPGNMLMLSGD-----QNQAP---TLSSEFKSTASLFGDAAKT-----------------------------FIVSPKELKKGLAQHK-----KLAKVVVG------KPQFQKPIMDDYYEDLTMNEPHSYNLPLQSQGNADEVPELLEQVELD--QMETQTQNPE--------NLQQEAPDYFPQSPEEDETLNKKEDPVHHQLYYALPTITGKPVDTQLKITSEPIKEVESSSYEEETPTQTPGPLVG-------------------------------AELFLSQQQQQPGEPSETPEEGESSGIDLESSIQPQEDSEEVGPLPTQQEDLSQHLGPVLEDESSLSELEQPIQLSESPEVVGSDSENQPEASVQPTVFPVVEQEAPFGAPESPIETVVETSPIPEIQPTQNENYQYHLPNVTVIPVDVTLTITLGPIKEVDSFLAQQEFPVHAIEYSNDIEPFLKEEEPPAQTSETPGESQFESQLEVPVQASEYDEELKSSATEQLAQFPENHGVTILPSNLYQTRHSSLSDVTGQPSDLAITITENPIEMGTSVYHDAAATPEEVEFLKTQQG------------VLSQSLEPILYDKPLSQQEDITGISQISEEGEPFPDQQETPEHSLELPTEEIAQPPGHHEVTGLPLGHGQVYSPASQNILTQYPTAPEEDQYSPVGQEVPNQLGEFSVEPSPSQQKLFPVLKPTAAQALKPPRVGNFSLIHNKIPHHSPKPLKNMVTDIPGHKMTVPRPDQDQGEYIISSNGSFQSLDLEVTVTSGITPETMHMLPTRTINPQIYSQVKISHPQHVETQHPNPAKTTVQPLDLELAINLQSTPKENFAQTLQETTTQLTGPLKEVTVQAPEHHEGTIPIPTQDQANYPRSPTVSFQSLDLEPTITPEANGEPYHPTVSQQIIIVHPPKHPLVIYSEQVHTQHPNPTEATAQPLNLELILTSQPTAEGELPQTLQDSTSQIIREPLIEVVALVPIYQEVTVQTPSQDQAEYLTSSTVSFQPLDLELSITPESTREPHLPTVPQQTIIVHPPKNPLVIHSEQVHTQHPNPTEATVQP--------------LDLQPTITPQPTAEGELLQTLQNSTGQITESPTAVAIPVPVYLDMTVPTLSQDQAEYLTSPTVSFQPLDLESTITPEPTREAEHFTTPKNTTAFPPKYTHMTLPQEVSVQHLKPTEGIVPPLNLELTITPQPATEGELSQTVQESTTQITEPHKEIIVPVPVFQEVTVPTPSQDQAEYQTFQHLNLELTSEPTKEAYRSTVSKTTITVNFPKRTQHPN--------PAEATDKPLDLELTIGSSYQSTAEGERFQETTTQISETPKQVVTPVPEYQEVAVSAPIQDQAKYPLLPTVSFHPLDLELTISSEPPREAYPTTTPDQTMVPPQKYPLGIYPGDAHIQHLNPTDITIQPLDLELTVHSQPTTEEEHSQSIRKNTTQITEPVKEVEALAPEGEDVTIPMPILEQTEFPTPNSVSLQSVDQELAILSDLPGWTYHPQKLKEIKRHTPGKIFLHYAEPPMGTVVETPDLFFLKTAKSKPVQETSIYITKSSKEIVARSPEHKEAVLPDPVEGQEKSLNPPNMSLKLLDQERIIPFLPRGLAQEPPNPKETKNHTPGKIFLHHAEHPIGMVAEPPDLFFLKSTKSKPTQKTPTQIKKLRKKVATHTLKYKKGMLTAPVEGQAESVPPPNMSLQPLDQELTISSQLPAWTHNSPNPKESRNHTPAKIFLHYAKPPMGTVVETPDPFFLKTSESKPVQETPTQITKSPKEVAAHTLEYKEGVVLAPVEGQAESVALPNMSLQALDQEFTISPQPPAWTHHPPNPKETKNHTPGKIFLHYAEPPMGMVVEPPDLFLLKTTKYNSVQKNPTQMTKSPKEILAQTPEYKEWVLPVPVEGQAESPTPPNMSLQLLDQEVIIPSLLSPPARDTPNPKETKTHTPGKIFPHYAEPPIRMSVEPPDLFFLRSTKSKSVQETPTQIINSPKDVTAPTREYKKGVLPASVEGQAESSLLPHISLQHLDQELIIPSLPPPQAHNPSNPKETKKYTPGKVFLYYADPPMGMVVEPPDLFFLETTNSKPVQETLTQISESPKEVAAQTLKYKKVVLPAPVQEQDESATSPKMSLQPLDQELTVSSQPPAWNHNPLNPKEIKNYAPGKISLHYAEPPMGTVVEPPDLFLLNTSKSNPGQENPTQITKSPKEVVGQTLDYKEGVLSGPIEGQDESPAPPSMSLQPLDQELTMSSQPPGYTHHSPNAAKTENHTPENNFFPYAEPPMGMVVQPPDLFFLKSTKSNLVQETPSLITKSPKEVAAHTLEYKKRLPPVPVEGQAESPPPPNISLQPLDQELTISSQPPGWTHHPPNPKETKNYTPGKIFLHYADTPLGMIVEPPDLFFLKTTTSEPVQETPSQITKLPKEIIAQTLEYKEGLLPVPFGGEDDSTTPPNVSLQPLDQEIIISFPSLGQAQQPPNVKESKEHQPEEILFHNAEPSMGTVVDLDLFFPKTMESKPVQEAPTQITKSPKEGVVQTLEYKELVVSSIIEGNVKYVTPNVSYRPLDLGLSESSGSTTEVYRSTTLNETTVPSSMHLQVPMPHLHSNFSVTQQPNTMAKHSSIMETPAHPSEIPVETVAQSVEYYPTIVLTSVYIETQHSNLSAIETAHSEVPTTTAPYPQAIYSEVPTTTGLYSEATHFGVSTTTAASPEITHSKAPETTALTPKWPGTTSLSPDQVEKHSSPTVQVLKMESTITPYSENSSTENDLTIEKSAYNYTKICDFCVCENETLLCVHLSPKWRLQQVPVPRPNTYNDTFVILNFKGNDISFIDKNVWKVYRWTEKLILSENHLTELHKESFEGLLSLQVLDLSCNKIRYIERGTFEPLPFLKYMNLGCNLLTELSFGTFQAWHGMQFLQQLILSRNPLAVVEDPYFFKLPALKYLDLGTTQVQLTTVESILIKTLELEHLILPSHMACCLCKFKADIEVICKTIKLHCHTGCLT---NTTRCLEEASIRNPEGAFMKVLQGRTGNTSTELIIEPERGNSDKDYANYSSSMDENIDLNDENDIMSALNYILPYFSEGNMEDIISSMLPFIKLLFSQEQDASNSLGSLQKDPERVPVTNESKTSNVTYKNKLNKHYFLENLLDTDTDEVQKEKKPGRHNAKSKNVGPKFKRQIFEKRWEPARAGEDSLAEIEKAERQLHSMSRVPKGTGSIQKRHFKDVSGKSLWSKQSVQTPVESISKDRQLG-------SPPSMELQQLGLEQKPRELVGYSFPSEPLLPKEHRGELSSSP--DLPLLDKAPTTNSLPDFIDRRKDLSYTIYVLESANANVKRAKGSNPSLQPEARHRNLR------------------KKKSHFQLIAKRP-AASSAVRSLISSPARGVFSSLGDLRYPERPFSELYVAPEPSTKKPLEENRAATDNVEENILEQIVTMPEETTSKNKSAKNPAADSDIPIPNIPGLIPPVLQTTKPPLHFIFGSDSPNNLEEFAYPSLMTPGEQFESHLNQQLRVLIPNNDVRRLISHVIRTLKMDCSDSQVQLSCAKLISRTGLLMKLLSEQQDFKLSRADWDTDQWKTENYINENTETQSKLKSLGRSQFGKEVSEFSYNNKVTLAISVTVVVIVLIIIFCLIEICSHRTKKGDKEKHKWR------KKYK---ERKNKEKYIWIRLPPRLRNILK-LDKKCGHDLRANTQDKLWEVKKRSSVKSSAES------------SEVAETPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NM11-1", "uniprot_id": "L37A2_HUMAN", "id": "A6NM11-1", "name": "Leucine-rich repeat-containing protein 37A2", "aln": "--MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWS------LAEIIGITRQLSTPQSQKQTLQNEYS--STDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNH----EVSVQPPGEDQAYYHLPNITVKPAD---------------------------------------------VEVTITSEPTNETESSQAQQETPIQFP---EEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVES---------------SPTQQETPGQPPEH--------HEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQS--------------------------PEPINNE------------------------------------------------------------------------NPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP---TQPPKKVVPQLRVYQGVTNPTPGQD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QAQHPVSPSVTVQ------------------------------------LLDLGLTIT----------------------------------------------------PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT---PKSMTEVEP-------------------------------------------------STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT----------------------------------------EVKPSPTTEETSTQ---------------------------------------PPDLGLAIIPEP-------------------------------------------------------------TTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQ-----------------------------------------------SESYTQNKALTAPEEHKASTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSACLT---NTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEP-SDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLD-VKSLLLPFIKLPTTG----------------------------------------------------------------------------------------NSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENAAEEKRLG-------SPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKVKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSEHFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFN--LGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQSEQKEKS-LELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKK-SSNEDKILNRDPGDS-------EAPTEEEESEALP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* * ..* . .. . . : . . :. :. : . . ..*:.*:: : :: ..* ** : : * . : .:. .** : : : : * : : .:*::.* : :*:* :* **. :* *. . . :: : * . * .:* *: . *:. **: * .:** : : * * *: : * ::... * . ::*: .** . :.: :: * ::. :: * *. .::* . . :. .*:. * . : : : . . . :: * **:* :*::*: .* ** :: * . *:. ::: ::* :* ***. . : . :: : : .. ... :* : * .*. . : : . . :.: *: . :. .* . .** . . :: . .. :. *: ** :.. *.. *. * . :** * * *: .:* . : . . ..:: * * : . . . :* * : *.:*::* * :. * * .*.* :*:**** .*.*::.*:.:* ** :*.******:******:** ********: *** ***.*****::.* **::***.*************::***.:***:.****::****:*****:*:* * ** ::.**: :***:*****.******:** .** :***:**:*::.* * ***:* : : :***:***.* .*. : :** :***. :* . . .*::* ***.*.:*:*.******* *:: : * :****** *:*:.. :. :.*. . *::*****:* :*: :*..*:.**. :::::* **.. *::* :* *. *. :. ::* :.::* :* . ..:...::**:. ** ***:::* :****:*.*..:* *:* ::.. : : :***::. : . **.:**:.*.::*.:****:* *.** * ...: :: :: :* : .:** : .. * *:*. ::* . . * ..* ** . .*:* . :* * :**:*** :*.*** ****::*****:***********.::**::********* ****** **:.* *: :******* *.****.**:*.: : :. .. . : * . : .* .: : * :::: : * . :: . :.* . :.. :. ", "identical_positions": 395, "similar_positions": 448, "identity": "10.27%" }, { "cls_id": "homologset.agr.HGNC:32406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BPW0-1", "uniprot_id": "IQCJ_MOUSE", "id": "Q8BPW0-1", "name": "IQ domain-containing protein J", "aln": "MRLEELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLSSSVSMNTFSDSSTPVS-----------------------------------VSRP--------------LAWTVLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1A5X6-1", "uniprot_id": "IQCJ_HUMAN", "id": "Q1A5X6-1", "name": "IQ domain-containing protein J", "aln": "MRLEELKRLQNPLEQVNDGKYSFENHQLAMDAENNIEKYPLNLQPLESKVKIIQRAWREYLQRQEPLGKRSPSPPSVSSEKLSSSVSMNTFSDSSTPFARAPVGKIHPYISWRLQSPGDKLPGGRKVILLYLDQLARPTGFIHTLKEPQIERLGFLTLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************:**** :********.*****:***.**********************:** ***********:*****************.: ::** *.: .*:", "identical_positions": 92, "similar_positions": 15, "identity": "57.86%" }, { "cls_id": "homologset.agr.HGNC:3241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUF2-1", "uniprot_id": "EGR4_MOUSE", "id": "Q9WUF2-1", "name": "Early growth response protein 4", "aln": "-------------------------------------------------------------------------------------------------------MLHLSDFSGSDALLSKPTEG-CAHASPELPRLPARDAPSAAAYPG-GDFLSWALSSCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDVPFPAGPDALLP---DLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGVPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPG-PAARLYQAGAYDTFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAAPPAQLSPLGLRGAATADFSKPLVADLPGGSGVAAP---SSPAASFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00911-1", "uniprot_id": "EGR4_RAT", "id": "Q00911-1", "name": "Early growth response protein 4", "aln": "-------------------------------------------------------------------------------------------------------MLHLSDFSGPDALLSKPTEG-CAHTSPELPRLPARDAPSAAAYPG-GDFLSWALSTCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPSPEAAASRSPLDVPFPAGPDALLP---DLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGAPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPG-PASRLYPPGAYDAFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAVPQAQLSPLGLRGAATADFSKALVADLPGGSGVAAP---SSPATSFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRTFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05215-1", "uniprot_id": "EGR4_HUMAN", "id": "Q05215-1", "name": "Early growth response protein 4", "aln": "MAVARGVGSPEPAPPQLYKWGGCGLGEPGSALERRGAAARGRCGRARAPRLPDSFPRGECPKPGARAPRSVRCGEPLPPASPPPARPQAQRARPRAPHSRRRAMLHLSEFSEPDALLVKSTEGCCAEPSAELPRLPARDAPAATGYPGAGDFLSWALNSCGASGDLADSCFLEGPAPTPPPGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAPFPEAFWEASPCAGAPSQCLYEPQLSPPDVKPGLRAPPASPALDAVS-AFKGPYAPWELLSVGAPGNCGSQGDYQAAPEARFPVIGTKIEDLLSISCPAELPAVPANRLYPSGAYDAFPLAPGDLGEGAEGLPGLLTPPSGEGGSSGDGGEFLASTQPQLSPLGLRSAAAADFPKPLVADIPGSSGVAAPPVPPPPPTPFPQAKARRKGRRGGKCSTRCFCPRPHAKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFASL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:** .**** *.*** **..*.***********:*:.*** ********.:***.***:*************.*************************************.***********.*****.***** *******.:*.********:*.********:************************.: *************.*.********.:*::*****..:***:*************. ** *** .****:*.*********:****.*****.*****.*:****** . .********.**:***.*.****:**.****** ..*.:.** **************:********.************:**********************************************************************************************:*", "identical_positions": 409, "similar_positions": 61, "identity": "69.32%" }, { "cls_id": "homologset.agr.HGNC:32411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR76-1", "uniprot_id": "D3ZR76_RAT", "id": "D3ZR76-1", "name": "", "aln": "MRTTLWTLSLG-SLLTLRAALIGTSSEDGQGNLRLAHRQSKCDGVVLVRHQGEWGHLCNLEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMVQPWLHNVSCWGNESSLWECSLGAWSQRACPHEWVVVALCANGTFREIRLVKGHSPCAGLPEIRNVNGVDRLCGLHVEEATVFCRELECGHALQAPRQDVGVS-KYMTCKGTEPTIRNCRLNNKLRGGCNLLLDAEVVCSGHVEARLVGGDHSCSGRLEVLRGLTWGTVCHADLDLPTAHVICRELGCGMAVSTLRGAQFGQGSGPVWLEAFRCVGNESMLFHCPQEPGHHCGHNQDVALTCSEFRLVNGSSDCEGRVELQVQGAWAPLCAANWDLADAMVLCHQLNCGNAVSIPPGGHFGDGDAPIWPDVFHCVGTEPHLLHCPASTLGAHSCVLGNTASTICSGLQDTLRLRDGQSYCDGRVEISLNGSWGRVLDDIWDIRGASVVCRQLECGEAQGAYDAPAPGFRTAPVGLSQVRCLGSETHLMQCNVSTSLLVPAATLRDAGVVCS----------------GSLRMRLAAGPGRCAGR-VEVFYQGSWGTVCDDAWDLQDAQVVCRQLDCGHALSAPGNAHFGAGTGRIWMDELHCLGNESLLWKCQSGNWGQHDCRHKEDAGVFCSESVALRLRGGTSGCVGWLDVLYNGSWGAVCSNALRDISLSIMCRQLGCGDQGWLENRPSPGPGLGISWVDKIKCRK-LHNATLWQCPSAPWNPHSCTQEEEVWINCEGLPQIGSQEPAQTPNCSSPLGCLEDSVLRVLGGEDGCSGRVELWHAGSWGTVCDDSWDLLDAQVVCRQLGCGQALAALEGAAFGPGMGPVWLDEVECLGSEVTLEACQAELWGHGDCTHKEDAGVRCAVKVQLFFCPTAPSLTPPPVAEAWNLPEVACLVLG-CLLGIVFLAMIAQWCHIRDASMGSG----------MLGNLQSDGVYEDIEVVPVMKKEENAISRLLMLEDGYDDAEEP---EGQPTESEEECNGHC----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1B0GSB0-1", "uniprot_id": "A0A1B0GSB0_MOUSE", "id": "A0A1B0GSB0-1", "name": "", "aln": "MRTTLWPLSLG-SLLTLGAALTGTSSEGDQGNLRLAHRQSTCDGVVLVRHQGEWGHLCNLEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMVRPWLHNVSCWGNESSLWECSLGAWSQRACPHEWVVVALCANGTFREIRLVKGHSPCAGLPEIMNVNGVDRLCGLHVEEATVFCRELQCGHALQAPRQDVGVS-KYMTCKGTESTIRNCRLNNKLRGGCNLLLDAEVICSGHVEARLVGGEHSCAGRLEVLRGLTWGTICHADLDLPTAHVVCRELGCGIAVSTLGGAQFGQGSGPVWLEAFRCVGNESLLFHCPREPGHHCGHEQDAALTCSEFRLVNGSSDCEGRVELQVQGTWAPVCAANWDLADAMVLCHQLNCGNAVSVPPGGHFGDGDDLIWPDIFHCVGTEPHLLHCAASTLGAHGCVLGNTASTICSGLQDILRLRDGQSYCDGRVEISLDGSWGRVLDDAWDLHGASVVCRQLGCGEAQRAYDAPAPIFRRVPVGLSQVRCLGSETRLVHCNVSTSLLVPAGTLRDAGVVCS----------------GSLRVRLAAGPGRCAGR-VELFYQGSWGTVCDDAWDLQDAQVVCRQLDCGHALSAPRNAHFGAGTGHIWMDELHCLGNESSLWKCQSGSWGQHDCRHKEDAGVFCSESVALRLRGGTSGCVGWLDVLYNGSWGAVCSNALRDISLSIICRQLGCGDQGWLENRPSSGAGLGISWVDNIKCRN-LHNATLWQCPSAPWNPHSCTQEEEVWINCEGTPQIALQDPAQTPNCSSPFGCLENSVLRVLGGEDGCSGRVELWHAGSWGTVCDDSWDLVDAEVVCRQLGCGQALAALGEASFGPGVGPVWLDEVECLGSEVTLEACQAEPWGHGDCTHKEDAGVRCAVKAQPSLCPTAPSLTPPSVAEVWKLSEIACLVLG-CLLGIVFLVMIAQWCHIRDASMGAG----------MLGHLQSEGIYEDIEVDPVPKKEENTVSRLLMLEEGYDDAEEP---EDQPTENDE----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0T1-1", "uniprot_id": "SRCRM_HUMAN", "id": "Q4G0T1-1", "name": "Scavenger receptor cysteine-rich domain-containing protein SCART1", "aln": "MRAALWTLGLGPLLLNLWAVPIG-----GPGALRLAYRHSTCDGVVLVRHHGAWGYVCNQEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMAQPWLHNVSCRGNESSLWECSLGSWCQSPCPHAWVVVALCSNGTFRELRLVKGRSPCAGLPEIRNVNGVDRLCVLHVEEAMVFCRELGCGPVLQAPRRDVGVVRKYLACRGTEPTIRSCRLDNNFRSGCDLRLDAEVVCSGHTEARLVGGEHPCAGRLEVT----WGTVCDAALDLATAHVVCRELQCGAVVSTPEGARFGRGSGPVWTEAFRCAGNESLLFHCPRGRGSQCGHGHDAGLRCSEFRMVNGSSSCEGRVEFQVQGSWAPLCATHWDIADATVLCHQLNCGNAVAAPGGGHFGDGDAAIWPDAFHCEGTESYLWNCPVSTLGAPACAPGNTASAVCSGLAHALRLREGQSRCDGRVEVSLDGVWGRVLDDAWDLRGAGVVCRQLGCRGAQQAYDAPAPSRGSVQVALSRVRCLGTETRLTQCNVSATLQEPAGTSRDAGVVCSGEVGTASPMARRHGIPGALTLSLHREPQGAAGRGAGALHGGAWGTVCDDAWDLRDAHVVCRQLGCGRALSALGAAHFGAGAGRIWLDELGCQGHESALWQCPSAGWGRHDWRHKEDAGVFCSESVALRLRGGTCCCAGWLDVFYNGTWGAMCSNALKDLSLSIICKQLGCG--VWGVGLAGEQALPLCGHRDRLGGQHRVPQAAQLHSVAMPFPPMAPALLR---PSRAGLSEDRPQAAGEPLNCSSWLGCPEEGALRVRGGEDRCSGRVELWHAGSWGTVCDDGWDLADAEVVCRQLGCGRAVAALGAAAFGPGSGPVWLDEVGCRGSEASLWGCPAERWGRGDRAHEEDAGVRCWEPGP------GPPLPAAPFRTFWVVSVVLGSLLGLLLLGLMAFLILPRVTQAMQRGLGRSEVSPGEAIYDVIGEMPPAGLYEEIMEAEAVLQDEEDGSVVKVDTEAAVSGEVSNLLEGQSIRAEGGHSRPVSQGYDEAAFPLEEMTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::**.*.** **.* *. * . * ****:*:*.*********:* **::** ********************************.:******** ************:*.* .*** *******:******:*****:********* ********* ****** ****** ** .*****:**** **::*:***.***.***:*::*.**:* *****:****.*******:*.*:***** ***:*.* ***.****:**** ** .*** **:**:****** *****.****:*****: * :*** :*..* *****:*****.******:****:***:**::**:*** ************: * ******** **** *** ***.:* :*..***** .*. *****::**** . ****:*** ******:**:* ******* **::**.****** * ** ******* . *.**:*****:**:* :****::* **.* ******** *:* : * * .*** . :: *:***********:**:******.**:**** ******:*:**:*** * *:** **:* *..**:** **********************. *.*****:***:***:*****:*:****:*:***** * . .. . . *.: :: : :*: :. : *: * : : . . * .: * ..:. **** :** *:..*** **** *******************.*** **:*********:*:*** *:**** ******** * ***.:* .* ** **:** :*:******* .*.*..... * :. : :** ***:: : ::.: : : .:* . ::*.: . *:**:* . ::*: * : : :. ..* . *.*. . : ", "identical_positions": 605, "similar_positions": 200, "identity": "57.78%" }, { "cls_id": "homologset.agr.HGNC:32414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4K7J2-1", "uniprot_id": "RBP2_DROME", "id": "A0A0B4K7J2-1", "name": "E3 SUMO-protein ligase RanBP2", "aln": "MFTTRKEVDAHVHKMLGKLQPGRERDIKGLAVARLYMKVQEYPKAIEYLNGYLRVRDDAVGHNMIATCYSRLNPPDVTEALQHYQRSIQIDPRQSEVVIDACELLVKENNASITECARYWLDQANSLDLSGNKQVFNLRMRVNLADSNGERDDTSGGDGEQNTLEILMYKELQARPQDVNIRIQLLRSYVEKMKIDQAFN--YALKTELESKNCTSQSNEWYEQIWMVLFKIEMAKDVKKNWRFWHFALHTLDR-LVQLSLEGSGLADSSKQLFRLDQYLFKFSTSIERSGDAPQRDLHQACIDHFTGQLLLHAVTLIFKREVLANKNKWMSTLRSALPLLLLGYQVRPIDDSSTNQWIKHCDAEQKQLIQMWRPQGAFRCAQLGRTLLGCLDRSQMEIKNDRENAEFDENKNSGNSMPGLFADSEELLASAHQQCLDKSWRSQIYQQLFTHAEHKLKDTSSHLVRNLRLQLPLFEWPNLAHIENYELQALVLPPHSLAQHVYLALGTDPNKLGDAPRVVFYEGFQRDVKQN--LNYCGQDSISQVDVDLYLYATTIQTRRKLQIQREVYDSSNLGNRNAAARPHMMPFANLVGQLGAPEQSNWWDLVVRLNSNQLITEGNRAEQRAQLQHGLEAVRGVNGPKADAIIIFQLGKILNSRSDRSSLEARIDTLYRQGFSILRHQHNQQMESYVRVFKYGSAGSTAAWQDLQSLAEEAVTYFSEKMFRIGQYEQFLDEVRGLHLPMAYFLQSEACHHLEESSKLPRTSRDRYSERRRECLQKTQKLIKNDDKHPLIAAMHRHQQDRNSRGIDNSFGSPDVHNNSSAYEDAEDDFYSHAAFSANRSRRQLEVTPVTPIVMAQPSQEMEQAVKQISKSLCVLKDDVSVGMEAMRQDIKVLTEKFTGLEDLLKKIKISSRDTPTRDVDPAAALGLDDLFIIEDALAEHQQQQQHQQQQSHNQGAIHPVVPNPYTSGFYNGMPNTPSAQERFLQGPYGSPMFNQNQMYNYYAAQAQAQAQAQFLRTPPAPGSIPPPNMFGPRNPNFGLPSMFPPPTVPSVAPYIDAMGNFTQPPPSLIPPPAQPAAPPAPLNILESKPVVALPTPGFFNTTTPVFGASPIQVPQSKPLTVPTVPIPSTAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQPTLSVTIPAQHIKPSLVQAPEQPAQSAQPAQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEEAEQNQSGATDPNKTLPQDTSADDYDPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFKSFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSAAPATSAPASATPFASFSFTPNGSSGFGTSTASPFGNLSFGTASAVGSGNNTTLFTTALIKDNTVQGKTLQQESQLNKSNSSDAEEEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNKVRLLMRREQVHKLCCNQRLLPETKFTYATNCKAAVTWGAQDYSDEELTTALLAVRFKSQDICQQFLEAVQKAQQSIGNEPKKEEVPSAAGEKEKPIKGFGDAFKPKAGSWNCQACYTNNGQDQLYCLACQEPKDATVPPKQSGLDQGNALNLTTSSSNKFSFGFASSATLPATGGFSFGGATQPKEKPAVAVVTASASAPTSVQTAALGFGKSSMTSGFGDAFKPAVGSWSCSACYVNNPGESLYCSACDAPKNDTVPQKEKSLGSGLNLPPTSKFSFGFGAAAAGDKDQAGDGATFNFAAMPAAVAPTTSIGSSSFTFSMTKPKPDQQQPNSTAAKEDEDNDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESD--WKERGLGDVKILRHRQTKKLRVVMRREQVFKICLNHVLNENVVYR--EKTETSWMFAVHDFSEGESVLERFTLRFKNKEVAQGFMEAIKNALNETAKPIEDSPVVGSVSQSTEANKPSQKNDGAAKSRGGESEVLDVGKTSSVRPTTHEVIPPLPMTLPLLTLPQPLAKPNDYQTPATILFKGSSLSRNNSSASEASKTPSSAFIFGSTDKSEPGKDAGPLANLQKLASGEGQGNVLGSIFRSGSSNENSSDGSVKFFFGGGNKAAEQQKKDSSESVFGGNKADSQSPATQEAPKLAFGGIAAPVFGDANPFGGHKVNLQKSDGKEEPKSIIGGTPLLFGGSNAFGIPKIETQSPAKDFVFGSAPAFGQMATFSFTAAKNEKEKDITSNNTTDLKAEGKEKKELVPETTSTFADLAKTGSTFADLASNPGGTFADLANKTGNDFANLSANSQGTTVGFNKSAGGGFYNLTHQNAFKNFESPQATEECDDDGDATTDDNYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVLEHPELQTFRLIMRQEQIHKLVLNMNISASLQMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTVNSCIKRAKALQGDEENKNDDAPEEQASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0DJD0-1", "uniprot_id": "RGPD1_HUMAN", "id": "P0DJD0-1", "name": "RANBP2-like and GRIP domain-containing protein 1", "aln": "---------MNVMGFNTDRLAWTRNKLRGFYFAKLYYEAKEYDLAKKYVCTYLSVQERDPRAHRFLGLLYELEEN-TEKAVECYRRSLELNPPQKDLVLKIAELLCKN--DVTDGRAKYWVERAAKLFP-GSPAIYKLKEHLLDCE----------GEDGWNKLFDWIQSELYVRPDDVHMNIRLVELYRSNKRLKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELS------ATFLEMKGHFYMHAGSLLLKMGQHGNNVQWQALSELAALCYVIAFQVP-------------------------RPKIKLIKGEAGQNLLEMMACDRLSQ--------------SGHMLLNLSRGKQDFLKEVVETFANKSGQSVLYNALFSSQSSK----DTSFLGSDDIGNIDVQEPELEDLARYDVGAIQAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSS--------YQPLCLPLP-VCKRLCTERQKSWWDAVCTLIHRKAVP-GNSAELRLVVQHEINTLRAQEKHGLQPALLVHWAKCLQKMGRG------LNSSYDQQEYIGRSVH-------------------------------------------------------------YWKKVLPLLKIIKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAVHGN-----IEDAVTAFESIKSVVSYWNLALIFHRKAEDIEN------------DAVFPEEQEECKNYLRKTRDYLIKIIDDSDSNLSVVKKLPVPLESVKEMLKSVMQELEDYSEGGP----------------LYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYS--------------------PKTPPRWAEDQNSLRKMICQEVKAITKLNSSKSASRHRWPTENYGPD---------------------------------------SVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAAN-----------------------------------------------------------------------------VTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKSEKPLENDTG-------------------------------------------------------------------------FQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFQFGKKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDACKTEDS-------DDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKILKNEVN-GKPRMLMRRDQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQKFEECQRLLLDIP--LQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTN-----------DQTKVTEEENKGSGTGAAGASDTTIKPNP------ENTGPTLEWDNYDLR-EDALDDNVSSSSVHDSPLASSPVRKNIFRFDES--TTGFNFSFKSALS--------------------------------------------------------------------------------------------LSKSPAKLNQSGTSVGTDEESDVTQ--EEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAELYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEK---DSLITPHVSRSSTP-------------------------------------------------------------------RESPCGKIAVAVLEETTRERTDVIQG------------------------------------------------------------DDVADAASEVEVSSTSETTTKAVVSPPKFVFG--------------------------------------------SESVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSNDSETSSVAQSGSESKVEPKK----------CELSKN---------------SDIEQSSDSKVKNLSAS----------------FPMEESSINYTFKTP-EKEPPLWHAEFTKEELVQKLSSTTKSADQLNGLLRETEATSAVLMEQIKLLKSEIRRLERNQEES--AANVEHLKNVLLQFIFLKPGSERESLLPVINTMLQLSPE-----------------------EKGKLAAVAQGLQETSIPKKK--------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . . ...::*: .*:** :.:** * :*: ** *:: : : .*: . :*:: *:**::::* *.::*:. .*** *: *:**:::* .* *. :::*: :: .: *:. *.* : .** .**:**::.*:*:. * .: ::.:*. : : :: :.. . .. : : * .:: :. *.:** : * *: *:*. .: :* : * :*. * . .:*: ..: . * : .:.*:: :** :*::* .*: :* : . * ::.:** **: : .: *:.** : .::. **: : .* ..:::* .. : :** :* :*: **: . * .: :: . : .: *:* .: .*:: *: ** : .:*.* :. . * : : *:: ::. *: . :**. :*::::* ... :: :*: : : :.** :* :*:. : :* : .*..*** * * .: :. ** ** * :** ::::*. : :. ::.: .* *:. . ::: * * * * * *: : . :: :...:*.. :.. : :* :: : ::* * :* :. : : *:::. : : :. :* : *: :* * *:.: .:* :: ::: . * : ** . .:..::: * . *:.:::::: *.. * : ::. .: :.: ::. * .: :: * . *: * .* : ::* :.:* ::: : .*. *.: :** : * . .. .: : .** . *..: : :*.:.:. : * :: :*.:. .:. *.: :*:::.*: :* .: :. :* :* :* : ... : :: ::*..: * . :. * :.* . * . **: . . . *:*:: . : ::: . ::::.: *::.* :* **: :*: **:*****.*.**:.: .**:*:* * .:********:*:*::..: .* *:****:** *:*.*: : . ::. :... * * *.*:** : . **.:**: ::.::* : .::.*: : : * :.* :. :. * : * : *:* : :: ** ::.* : * ** . ..* : * ... .:.. ..:.: .:: : : * *. *.:.*:. : *.:* *:**. :**.*:. ::*. .. :*..::...::*.: :* ***.:. **.**:**** ::*.:***:*:::: *:*:*** ::. *****:**:***:: :.*::*:****:**:*:* ** :. :: : : ** *:::. **::** :*::::*** ::**:.* : :.:* . * ** :. **:*: . : *. .: :. * :. : .* * :: *::..* ...::: : *. ..**:.** : .: :* :.. :: *.**.:.* *.: ***.*. :.::.: :* :. ::: : ** .:*:*. :*: :.:.... ****. : : ... .*::* .* ..: *.:: : .: . : : * : :: *: ** : : . : ::. :** : :::*: : .: * *.: **:. :* * :* : : .*..: ", "identical_positions": 378, "similar_positions": 744, "identity": "13.86%" }, { "cls_id": "homologset.agr.HGNC:32415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4K7J2-1", "uniprot_id": "RBP2_DROME", "id": "A0A0B4K7J2-1", "name": "E3 SUMO-protein ligase RanBP2", "aln": "MFTTRKEVDAHVHKMLGKLQPGRERDIKGLAVARLYMKVQEYPKAIEYLNGYLRVRDDAVGHNMIATCYSRLNPPDVTEALQHYQRSIQIDPRQSEVVIDACELLVKENNASITECARYWLDQANSLDLSGNKQVFNLRMRVNLADSNGERDDTSGGDGEQNTLEILMYKELQARPQDVNIRIQLLRSYVEKMKIDQAFN--YALKTELESKNCTSQSNEWYEQIWMVLFKIEMAKDVKKNWRFWHFALHTLDR-LVQLSLEGSGLADSSKQLFRLDQYLFKFSTSIERSGDAPQRDLHQACIDHFTGQLLLHAVTLIFKREVLANKNKWMSTLRSALPLLLLGYQVRPIDDSSTNQWIKHCDAEQKQLIQMWRPQGAFRCAQLGRTLLGCLDRSQMEIKNDRENAEFDENKNSGNSMPGLFADSEELLASAHQQCLDKSWRSQIYQQLFTHAEHKLKDTSSHLVRNLRLQLPLFEWPNLAHIENYELQALVLPPHSLAQHVYLALGTDPNKLGDAPRVVFYEGFQRDVKQN--LNYCGQDSISQVDVDLYLYATTIQTRRKLQIQREVYDSSNLGNRNAAARPHMMPFANLVGQLGAPEQSNWWDLVVRLNSNQLITEGNRAEQRAQLQHGLEAVRGVNGPKADAIIIFQLGKILNSRSDRSSLEARIDTLYRQGFSILRHQHNQQMESYVRVFKYGSAGSTAAWQDLQSLAEEAVTYFSEKMFRIGQYEQFLDEVRGLHLPMAYFLQSEACHHLEESSKLPRTSRDRYSERRRECLQKTQKLIKNDDKHPLIAAMHRHQQDRNSRGIDNSFGSPDVHNNSSAYEDAEDDFYSHAAFSANRSRRQLEVTPVTPIVMAQPSQEMEQAVKQISKSLCVLKDDVSVGMEAMRQDIKVLTEKFTGLEDLLKKIKISSRDTPTRDVDPAAALGLDDLFIIEDALAEHQQQQQHQQQQSHNQGAIHPVVPNPYTSGFYNGMPNTPSAQERFLQGPYGSPMFNQNQMYNYYAAQAQAQAQAQFLRTPPAPGSIPPPNMFGPRNPNFGLPSMFPPPTVPSVAPYIDAMGNFTQPPPSLIPPPAQPAAPPAPLNILESKPVVALPTPGFFNTTTPVFGASPIQVPQSKPLTVPTVPIPSTAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQPTLSVTIPAQHIKPSLVQAPEQPAQSAQPAQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEEAEQNQSGATDPNKTLPQDTSADDYDPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFKSFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSAAPATSAPASATPFASFSFTPNGSSGFGTSTASPFGNLSFGTASAVGSGNNTTLFTTALIKDNTVQGKTLQQESQLNKSNSSDAEEEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNKVRLLMRREQVHKLCCNQRLLPETKFTYATNCKAAVTWGAQDYSDEELTTALLAVRFKSQDICQQFLEAVQKAQQSIGNEPKKEEVPSAAGEKEKPIKGFGDAFKPKAGSWNCQACYTNNGQDQLYCLACQEPKDATVPPKQSGLDQGNALNLTTSSSNKFSFGFASSATLPATGGFSFGGATQPKEKPAVAVVTASASAPTSVQTAALGFGKSSMTSGFGDAFKPAVGSWSCSACYVNNPGESLYCSACDAPKNDTVPQKEKSLGSGLNLPPTSKFSFGFGAAAAGDKDQAGDGATFNFAAMPAAVAPTTSIGSSSFTFSMTKPKPDQQQPNSTAAKEDEDNDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESD--WKERGLGDVKILRHRQTKKLRVVMRREQVFKICLNHVLNENVVYR--EKTETSWMFAVHDFSEGESVLERFTLRFKNKEVAQGFMEAIKNALNETAKPIEDSPVVGSVSQSTEANKPSQKNDGAAKSRGGESEVLDVGKTSSVRPTTHEVIPPLPMTLPLLTLPQPLAKPNDYQTPATILFKGSSLSRNNSSASEASKTPSSAFIFGSTDKSEPGKDAGPLANLQKLASGEGQGNVLGSIFRSGSSNENSSDGSVKFFFGGGNKAAEQQKKDSSESVFGGNKADSQSPATQEAPKLAFGGIAAPVFGDANPFGGHKVNLQKSDGKEEPKSIIGGTPLLFGGSNAFGIPKIETQSPAKDFVFGSAPAFGQMATFSFTAAKNEKEKDITSNNTTDLKAEGKEKKELVPETTSTFADLAKTGSTFADLASNPGGTFADLANKTGNDFANLSANSQGTTVGFNKSAGGGFYNLTHQNAFKNFESPQATEECDDDGDATTDDNYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVLEHPELQTFRLIMRQEQIHKLVLNMNISASLQMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTVNSCIKRAKALQGDEENKNDDAPEEQASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0DJD1-1", "uniprot_id": "RGPD2_HUMAN", "id": "P0DJD1-1", "name": "RANBP2-like and GRIP domain-containing protein 2", "aln": "-MRRSKAYGERYLASVQGSAPSPGKKLRGFYFAKLYYEAKEYDLAKKYVCTYLSVQERDPRAHRFLGLLYELEEN-TEKAVECYRRSLELNPPQKDLVLKIAELLCKN--DVTDGRAKYWVERAAKLFP-GSPAIYKLKEHLLDCE----------GEDGWNKLFDWIQSELYVRPDDVHMNIRLVELYRSNKRLKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELS------ATFLEMKGHFYMHAGSLLLKMGQHGNNVQWQALSELAALCYVIAFQVP-------------------------RPKIKLIKGEAGQNLLEMMACDRLSQ--------------SGHMLLNLSRGKQDFLKEVVETFANKSGQSVLYNALFSSQSSK----DTSFLGSDDIGNIDVQEPELEDLARYDVGAIQAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSS--------YQPLCLPLP-VCKRLCTERQKSWWDAVCTLIHRKAVP-GNSAELRLVVQHEINTLRAQEKHGLQPALLVHWAKCLQKMGRG------LNSSYDQQEYIGRSVH-------------------------------------------------------------YWKKVLPLLKIIKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAVHGN-----IEDAVTAFESIKSVVSYWNLALIFHRKAEDIEN------------DAVFPEEQEECKNYLRKTRDYLIKIIDDSDSNLSVVKKLPVPLESVKEMLKSVMQELEDYSEGGP----------------LYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYS--------------------PKTPPRWAEDQNSLRKMICQEVKAITKLNSSKSASRHRWPTENYGPD---------------------------------------SVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAAN-----------------------------------------------------------------------------VTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKSEKPLENDTG-------------------------------------------------------------------------FQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFQFGKKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDACKTEDS-------DDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKILKNEVN-GKPRMLMRRDQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQKFEECQRLLLDIP--LQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTN-----------DQTKVTEEENKGSGTGAAGASDTTIKPNP------ENTGPTLEWDNYDLR-EDALDDNVSSSSVHDSPLASSPVRKNIFRFDES--TTGFNFSFKSALS--------------------------------------------------------------------------------------------LSKSPAKLNQSGTSVGTDEESDVTQ--EEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHMAELYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEK---DSLITPHVSRSSTP-------------------------------------------------------------------RESPCGKIAVAVLEETTRERTDVIQG------------------------------------------------------------DDVADAASEVEVSSTSETTTKAVVSPPKFVFG--------------------------------------------SESVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSNDSETSSVAQSGSESKVEPKK----------CELSKN---------------SDIEQSSDSKVKNLSAS----------------FPMEESSINYTFKTP-EKEPPLWHAEFTKEELVQKLSSTTKSADQLNGLLRETEATSAVLMEQIKLLKSEIRRLERNQEES--AANVEHLKNVLLQFIFLKPGSERESLLPVINTMLQLSPE-----------------------EKGKLAAVAQGLQETSIPKKK--------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : : *. :.::*: .*:** :.:** * :*: ** *:: : : .*: . :*:: *:**::::* *.::*:. .*** *: *:**:::* .* *. :::*: :: .: *:. *.* : .** .**:**::.*:*:. * .: ::.:*. : : :: :.. . .. : : * .:: :. *.:** : * *: *:*. .: :* : * :*. * . .:*: ..: . * : .:.*:: :** :*::* .*: :* : . * ::.:** **: : .: *:.** : .::. **: : .* ..:::* .. : :** :* :*: **: . * .: :: . : .: *:* .: .*:: *: ** : .:*.* :. . * : : *:: ::. *: . :**. :*::::* ... :: :*: : : :.** :* :*:. : :* : .*..*** * * .: :. ** ** * :** ::::*. : :. ::.: .* *:. . ::: * * * * * *: : . :: :...:*.. :.. : :* :: : ::* * :* :. : : *:::. : : :. :* : *: :* * *:.: .:* :: ::: . * : ** . .:..::: * . *:.:::::: *.. * : ::. .: :.: ::. * .: :: * . *: * .* : ::* :.:* ::: : .*. *.: :** : * . .. .: : .** . *..: : :*.:.:. : * :: :*.:. .:. *.: :*:::.*: :* .: :. :* :* :* : ... : :: ::*..: * . :. * :.* . * . **: . . . *:*:: . : ::: . ::::.: *::.* :* **: :*: **:*****.*.**:.: .**:*:* * .:********:*:*::..: .* *:****:** *:*.*: : . ::. :... * * *.*:** : . **.:**: ::.::* : .::.*: : : * :.* :. :. * : * : *:* : :: ** ::.* : * ** . ..* : * ... .:.. ..:.: .:: : : * *. *.:.*:. : *.:* *:**. :**.*:. ::*. .. :*..::...::*.: :* ***.:. **.**:**** ::*.:***:*:::: * *:*** ::. *****:**:***:: :.*::*:****:**:*:* ** :. :: : : ** *:::. **::** :*::::*** ::**:.* : :.:* . * ** :. **:*: . : *. .: :. * :. : .* * :: *::..* ...::: : *. ..**:.** : .: :* :.. :: *.**.:.* *.: ***.*. :.::.: :* :. ::: : ** .:*:*. :*: :.:.... ****. : : ... .*::* .* ..: *.:: : .: . : : * : :: *: ** : : . : ::. :** : :::*: : .: * *.: **:. :* * :* : : .*..: ", "identical_positions": 379, "similar_positions": 743, "identity": "13.9%" }, { "cls_id": "homologset.agr.HGNC:32416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4K7J2-1", "uniprot_id": "RBP2_DROME", "id": "A0A0B4K7J2-1", "name": "E3 SUMO-protein ligase RanBP2", "aln": "MFTTRKEVDAHVHKMLGKLQPGRERDIKGLAVARLYMKVQEYPKAIEYLNGYLRVRDDAVGHNMIATCYSRLNPPDVTEALQHYQRSIQIDPRQSEVVIDACELLVKENNASITECARYWLDQANSLDLSGNKQVFNLRMRVNLADSNGERDDTSGGDGEQNTLEILMYKELQARPQDVNIRIQLLRSYVEKMKIDQAFN--YALKTELESKNCTSQSNEWYEQIWMVLFKIEMAKDVKKNWRFWHFALHTLDR-LVQLSLEGSGLADSSKQLFRLDQYLFKFSTSIERSGDAPQRDLHQACIDHFTGQLLLHAVTLIFKREVLANKNKWMSTLRSALPLLLLGYQVRPIDDSSTNQWIKHCDAEQKQLIQMWRPQGAFRCAQLGRTLLGCLDRSQMEIKNDRENAEFDENKNSGNSMPGLFADSEELLASAHQQCLDKSWRSQIYQQLFTHAEHKLKDTSSHLVRNLRLQLPLFEWPNLAHIENYELQALVLPPHSLAQHVYLALGTDPNKLGDAPRVVFYEGFQRDVKQN--LNYCGQDSISQVDVDLYLYATTIQTRRKLQIQREVYDSSNLGNRNAAARPHMMPFANLVGQLGAPEQSNWWDLVVRLNSNQLITEGNRAEQRAQLQHGLEAVRGVNGPKADAIIIFQLGKILNSRSDRSSLEARIDTLYRQGFSILRHQHNQQMESYVRVFKYGSAGSTAAWQDLQSLAEEAVTYFSEKMFRIGQYEQFLDEVRGLHLPMAYFLQSEACHHLEESSKLPRTSRDRYSERRRECLQKTQKLIKNDDKHPLIAAMHRHQQDRNSRGIDNSFGSPDVHNNSSAYEDAEDDFYSHAAFSANRSRRQLEVTPVTPIVMAQPSQEMEQAVKQISKSLCVLKDDVSVGMEAMRQDIKVLTEKFTGLEDLLKKIKISSRDTPTRDVDPAAALGLDDLFIIEDALAEHQQQQQHQQQQSHNQGAIHPVVPNPYTSGFYNGMPNTPSAQERFLQGPYGSPMFNQNQMYNYYAAQAQAQAQAQFLRTPPAPGSIPPPNMFGPRNPNFGLPSMFPPPTVPSVAPYIDAMGNFTQPPPSLIPPPAQPAAPPAPLNILESKPVVALPTPGFFNTTTPVFGASPIQVPQSKPLTVPTVPIPSTAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQPTLSVTIPAQHIKPSLVQAPEQPAQSAQPAQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEEAEQNQSGATDPNKTLPQDTSADDYDPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFKSFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSAAPATSAPASATPFASFSFTPNGSSGFGTSTASPFGNLSFGTASAVGSGNNTTLFTTALIKDNTVQGKTLQQESQLNKSNSSDAEEEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNKVRLLMRREQVHKLCCNQRLLPETKFTYATNCKAAVTWGAQDYSDEELTTALLAVRFKSQDICQQFLEAVQKAQQSIGNEPKKEEVPSAAGEKEKPIKGFGDAFKPKAGSWNCQACYTNNGQDQLYCLACQEPKDATVPPKQSGLDQGNALNLTTSSSNKFSFGFASSATLPATGGFSFGGATQPKEKPAVAVVTASASAPTSVQTAALGFGKSSMTSGFGDAFKPAVGSWSCSACYVNNPGESLYCSACDAPKNDTVPQKEKSLGSGLNLPPTSKFSFGFGAAAAGDKDQAGDGATFNFAAMPAAVAPTTSIGSSSFTFSMTKPKPDQQQPNSTAAKEDEDNDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESD--WKERGLGDVKILRHRQTKKLRVVMRREQVFKICLNHVLNENVVYR--EKTETSWMFAVHDFSEGESVLERFTLRFKNKEVAQGFMEAIKNALNETAKPIEDSPVVGSVSQSTEANKPSQKNDGAAKSRGGESEVLDVGKTSSVRPTTHEVIPPLPMTLPLLTLPQPLAKPNDYQTPATILFKGSSLSRNNSSASEASKTPSSAFIFGSTDKSEPGKDAGPLANLQKLASGEGQGNVLGSIFRSGSSNENSSDGSVKFFFGGGNKAAEQQKKDSSESVFGGNKADSQSPATQEAPKLAFGGIAAPVFGDANPFGGHKVNLQKSDGKEEPKSIIGGTPLLFGGSNAFGIPKIETQSPAKDFVFGSAPAFGQMATFSFTAAKNEKEKDITSNNTTDLKAEGKEKKELVPETTSTFADLAKTGSTFADLASNPGGTFADLANKTGNDFANLSANSQGTTVGFNKSAGGGFYNLTHQNAFKNFESPQATEECDDDGDATTDDNYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVLEHPELQTFRLIMRQEQIHKLVLNMNISASLQMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTVNSCIKRAKALQGDEENKNDDAPEEQASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NKT7-1", "uniprot_id": "RGPD3_HUMAN", "id": "A6NKT7-1", "name": "RanBP2-like and GRIP domain-containing protein 3", "aln": "MSCSKAYGERYVASVQGSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDPRAHRFLGLLYELEEN-TEKAVECYRRSVELNPTQKDLVLKIAELLCKN--DVTDGRAEYWVERAAKLFP-GSPAIYKLKEQLLDCE----------GEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKRLKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELS------ATFLEMKGHFYMHAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVP-------------------------RPKIKLIKGEAGQNLLEMMACDRLSQ--------------SGHMLLNLSRGKQDFLKVVVETFANKSGQSALYDALFSSQSPK----DTSFLGSDDIGNIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSS--------YQPLCLPLP-VCKQLCTERQKSWWDAVCTLIHRKAVP-GNSAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKCLQKMG------SGLNSFYDQ----------------------------------REYIGRSVHYWKKVLP--------------------------LLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHVTFAILDAVNGN-----IEDAMTAFESIKSVVSYWNLALIFHRKAEDIAN------------DALSPEEQEECKNYLRKTRGYLIKILDDSDSNLSVVKKLPVPLESVKEMLKSVMQELENYSEGGP----------------LYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYSP---KTPPRWAEDQNSLLKMIRQEVKAIKEEMQELKLNSSKSASHHRWPTENYGPDSVP--------------------------------------------------DGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAAN-----------------------------------------------------------------------------VTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENDTG-------------------------------------------------------------------------LQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFQFGKKDLNFKGFSGAGEKLFSSQYGKMANKANTSGDFEKDDDAYKTEDS-------DDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVSQWKERGLGNLKILKNEVN-GKVRMLMQREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIP--LQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTN-----------DQTKVAEEENKGSGTG-------------------------------------------------AAGASDTTIKPNAENTG--------------PTLEWDNYDLREDALDDSVSSSSVHASP--------------LASSPVRKNLFHFDESTTG--------------------------SNFSFKSALSLSKSPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEFYRYDKDVGQWKERGIGDIKILQNYDNKHVRILMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEK---DSLITPHVSRSSTP-------------------------------------------------------------------RESPCGKIAVAVLEETTRERTDVIQG------------------------------------------------------------DDVADAASEVEVSSTSETTTKAVVSPPKFVFG--------------------------------------------SESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKK----------CELSKN---------------SDIEQSSDSKVKNLSASFPTEES-----------SINYTFKTPEKEPPLWYAEFTKEELVQKLSSTTKSADHLNGLLREIEATN------AVLMEQIKLLKSEIRRLERNQEQEVSAANVEHLKNVLLQFIFLKPGSERERLLPVINTMLQLSLEEKGKLAAVAQGEE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : :* .: *. . *::. :*: .*:** :.:** * :*: *:.**: : : .*: . :*:: *:**::::* *.::*:. .*** *: *.**:::* .* *. :::*: :: .: *:. *.* *: .** .**:**::.*:*:. * .. ::.:*. : : :: :.. . .. : : * .:: :. *.:** : * *: *:*. .: :* : * :*. * . .:*: ..: . * : .:.*:: :** :*::* .*: :* : . * *:.:** **: : .: *:.** : .::. **: : .* ..:::* . : :** :* :*: **: . * .: :: . : .: *:* .: .*:: *: ** : .:*.* :. . * : : *:: ::. *: . :**. :*::::* ... :: :*: : : :.** :* :*:. : ** : .*..*** * * .: :. ** *: * :** ::::*. : :. ::.: .* *:. . : ::::* * :. .:* *:.: : : :::...:*.. :.. : :* :: : ::* * :* :. : : *:::: : : :. :* : *: :* ** : .: .:* :: ::: * : ** . .:..::: * . *:.:::::: *.. * : ::. .: :.: ::. * .: :: * . *:. : *. .. *: :*: . :::* : .::: :: :: .*.*:* . .. .: : .** . *..: : :*.:.:. : * :: :*.:. .:. *.: :*:.:.*: :* .: :. :* :* :* : ... : :: ::*..: * . :. * :.* . * . **: .:. . *:*:: . : ::: . ::::.: *::.* :* **: :*: **:*****.*.**:.: .**:*:* *..:********:*:*::..: .***:**:**** *:*.*: : . ::. :... * *.*.*:** : . **.:**: ::.::* : .::.*: : : * :.* :. :. * : * : *:* : :: ** ::.* * * ** . *:.:: *:::. * . * .. .*. : .:*: .*: .*. * .*. * * *. :::* .. **. ::: .*. : :* :: :::.. ***.:. **.**:**** ::*.:***:*:::: *:*::** ::. *****:**:***:: :.*::*::***:**:*:* ** :. :: : : ** *:::. **::** :*::::*** ::**:.* : :.:* . * ** :. **:*: . : *. .: :. * :. : .* * :: *::..* ...::: : *. ..**:.** : .: :* :.. :* *.**.:.* *.: ***.*. :.::.: :* :. ::: : ** .:*:*. :*: :.:.... ****. .:.: : *.* * .: . . .. * : * ** .*. :: *: ** : : . : ::. . :** : :::*: : .: * *.: **:. : : : * : ", "identical_positions": 380, "similar_positions": 744, "identity": "13.93%" }, { "cls_id": "homologset.agr.HGNC:32417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4K7J2-1", "uniprot_id": "RBP2_DROME", "id": "A0A0B4K7J2-1", "name": "E3 SUMO-protein ligase RanBP2", "aln": "MFTTRKEVDAHVHKMLGKLQPGRERDIKGLAVARLYMKVQEYPKAIEYLNGYLRVRDDAVGHNMIATCYSRLNPPDVTEALQHYQRSIQIDPRQSEVVIDACELLVKENNASITECARYWLDQANSLDLSGNKQVFNLRMRVNLADSNGERDDTSGGDGEQNTLEILMYKELQARPQDVNIRIQLLRSYVEKMKIDQAFN--YALKTELESKNCTSQSNEWYEQIWMVLFKIEMAKDVKKNWRFWHFALHTLDR-LVQLSLEGSGLADSSKQLFRLDQYLFKFSTSIERSGDAPQRDLHQACIDHFTGQLLLHAVTLIFKREVLANKNKWMSTLRSALPLLLLGYQVRPIDDSSTNQWIKHCDAEQKQLIQMWRPQGAFRCAQLGRTLLGCLDRSQMEIKNDRENAEFDENKNSGNSMPGLFADSEELLASAHQQCLDKSWRSQIYQQLFTHAEHKLKDTSSHLVRNLRLQLPLFEWPNLAHIENYELQALVLPPHSLAQHVYLALGTDPNKLGDAPRVVFYEGFQRDVKQN--LNYCGQDSISQVDVDLYLYATTIQTRRKLQIQREVYDSSNLGNRNAAARPHMMPFANLVGQLGAPEQSNWWDLVVRLNSNQLITEGNRAEQRAQLQHGLEAVRGVNGPKADAIIIFQLGKILNSRSDRSSLEARIDTLYRQGFSILRHQHNQQMESYVRVFKYGSAGSTAAWQDLQSLAEEAVTYFSEKMFRIGQYEQFLDEVRGLHLPMAYFLQSEACHHLEESSKLPRTSRDRYSERRRECLQKTQKLIKNDDKHPLIAAMHRHQQDRNSRGIDNSFGSPDVHNNSSAYEDAEDDFYSHAAFSANRSRRQLEVTPVTPIVMAQPSQEMEQAVKQISKSLCVLKDDVSVGMEAMRQDIKVLTEKFTGLEDLLKKIKISSRDTPTRDVDPAAALGLDDLFIIEDALAEHQQQQQHQQQQSHNQGAIHPVVPNPYTSGFYNGMPNTPSAQERFLQGPYGSPMFNQNQMYNYYAAQAQAQAQAQFLRTPPAPGSIPPPNMFGPRNPNFGLPSMFPPPTVPSVAPYIDAMGNFTQPPPSLIPPPAQPAAPPAPLNILESKPVVALPTPGFFNTTTPVFGASPIQVPQSKPLTVPTVPIPSTAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQPTLSVTIPAQHIKPSLVQAPEQPAQSAQPAQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEEAEQNQSGATDPNKTLPQDTSADDYDPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFKSFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSAAPATSAPASATPFASFSFTPNGSSGFGTSTASPFGNLSFGTASAVGSGNNTTLFTTALIKDNTVQGKTLQQESQLNKSNSSDAEEEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNKVRLLMRREQVHKLCCNQRLLPETKFTYATNCKAAVTWGAQDYSDEELTTALLAVRFKSQDICQQFLEAVQKAQQSIGNEPKKEEVPSAAGEKEKPIKGFGDAFKPKAGSWNCQACYTNNGQDQLYCLACQEPKDATVPPKQSGLDQGNALNLTTSSSNKFSFGFASSATLPATGGFSFGGATQPKEKPAVAVVTASASAPTSVQTAALGFGKSSMTSGFGDAFKPAVGSWSCSACYVNNPGESLYCSACDAPKNDTVPQKEKSLGSGLNLPPTSKFSFGFGAAAAGDKDQAGDGATFNFAAMPAAVAPTTSIGSSSFTFSMTKPKPDQQQPNSTAAKEDEDNDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESD--WKERGLGDVKILRHRQTKKLRVVMRREQVFKICLNHVLNENVVYR--EKTETSWMFAVHDFSEGESVLERFTLRFKNKEVAQGFMEAIKNALNETAKPIEDSPVVGSVSQSTEANKPSQKNDGAAKSRGGESEVLDVGKTSSVRPTTHEVIPPLPMTLPLLTLPQPLAKPNDYQTPATILFKGSSLSRNNSSASEASKTPSSAFIFGSTDKSEPGKDAGPLANLQKLASGEGQGNVLGSIFRSGSSNENSSDGSVKFFFGGGNKAAEQQKKDSSESVFGGNKADSQSPATQEAPKLAFGGIAAPVFGDANPFGGHKVNLQKSDGKEEPKSIIGGTPLLFGGSNAFGIPKIETQSPAKDFVFGSAPAFGQMATFSFTAAKNEKEKDITSNNTTDLKAEGKEKKELVPETTSTFADLAKTGSTFADLASNPGGTFADLANKTGNDFANLSANSQGTTVGFNKSAGGGFYNLTHQNAFKNFESPQATEECDDDGDATTDDNYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVLEHPELQTFRLIMRQEQIHKLVLNMNISASLQMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTVNSCIKRAKALQGDEENKNDDAPEEQASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7Z3J3-1", "uniprot_id": "RGPD4_HUMAN", "id": "Q7Z3J3-1", "name": "RanBP2-like and GRIP domain-containing protein 4", "aln": "MSCSKAYGERYVASVQGSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDPRAHRFLGLLYELEEN-TEKAVECYRRSVELNPTQKDLVLKIAELLCKN--DVTDGRAKYWVERAAKLFP-GSPAIYKLKEQLLDCE----------GEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKRLKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELS------ATFLEMKGHFYMHAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVP-------------------------RPKIKLIKGEAGQNLLEMMACDRLSQ--------------SGHMLLNLSRGKQDFLKVVVETFANKSGQSALYDALFSSQSPK----DTSFLGSDDIGNIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSS--------YQPLCLPLP-VCKQLCTERQKSWWDAVCTLIHRKAVP-GNSAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKCLQKMG------SGLNSFYDQ----------------------------------REYIGRSVHYWKKVLP--------------------------LLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHVTFAILDAVNGN-----IEDAMTAFESIKSVVSYWNLALIFHRKAEDIAN------------DALSPEEQEECKNYLRKTRGYLIKILDDSDSNLSVVKKLPVPLESVKEMLKSVMQELENYSEGDP----------------LYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYSP---KTPPRWAEDQNSLLKMIRQEVKAIKEEMQELKLNSSKSASHHRWPTENYGPDSVP--------------------------------------------------DGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAAN-----------------------------------------------------------------------------VTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKESEKPLENDTG-------------------------------------------------------------------------FQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFQFGKKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDAYKTEDS-------DDIHFEPVVQMPEKVELVIGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVN-GKPRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQQLLLDIP--LQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTN-----------DQTKVTEEENKGSGTGAAGASDTTIKPN-------------PENTGPTLEWDN---------------------------------------------------------------CDLREDALDDSVSS-SSVHASPLASSPVRKNLFHFGESTTG--------------------------SNFSFKSALSPSKSPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEKVVFSHRAELYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHTITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEK---DSLITPHVSRSSTP-------------------------------------------------------------------RESPCGKIAVAVLEETTRERTDVIQG------------------------------------------------------------DDVADAASEVEVSSTSETTTKAVVSPPKFVFG--------------------------------------------SESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNASLKSNNSETSSVAQSGSESKVEPKK----------CELSKN---------------SDIEQSSDSKVKNLSAS----------------FPMEESSINYTFKTP-EKEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLREAEATSAVLMEQIKLLKSEIRRLERNQEQEESAANVEHLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : :* .: *. . *::. :*: .*:** :.:** * :*: *:.**: : : .*: . :*:: *:**::::* *.::*:. .*** *: *:**:::* .* *. :::*: :: .: *:. *.* *: .** .**:**::.*:*:. * .. ::.:*. : : :: :.. . .. : : * .:: :. *.:** : * *: *:*. .: :* : * :*. * . .:*: ..: . * : .:.*:: :** :*::* .*: :* : . * *:.:** **: : .: *:.** : .::. **: : .* ..:::* . : :** :* :*: **: . * .: :: . : .: *:* .: .*:: *: ** : .:*.* :. . * : : *:: ::. *: . :**. :*::::* ... :: :*: : : :.** :* :*:. : ** : .*..*** * * .: :. ** *: * :** ::::*. : :. ::.: .* *:. . : ::::* * :. .:* *:.: : : :::...:*.. :.. : :* :: : ::* * :* :. : : *:::: : : :. :* : *: :* ** : .: .:* :: ::: * : ** . .:..::: * . *:.:::::: *.. * : ::. .: :.: ::. * .: :: * . *:. : *. .. *: :*: . :::* : .::: :: :: .*.*:* . .. .: : .** . *..: : :*.:.:. : * :: :*.:. .:. *.: :*:.:.*: :* .: :. :* :* :* : ... : :: ::*..: * . :. * :.* . * . **: . . . *:*:: . : ::: . ::::.: *::.* :* **: :*: **:* ***.*.**:.: .**:*:* *..:********:*:*::..: .* *:******* *:*.*: : . ::. :... * *.*.*:** : . **.:**: ::.::* : .::.** : : * :.* :. :. * : * : *:* : :: ** ::.* : * ** . ..* : * ... * . * :: . *. : . :*:*.. .. .* * .*. * * ** :::* .. **. ::: .*. : :* :: :::.. ***.:. **.**:**** ::*.:***:*:::: *:*:*** ::. *****:**:***:: :.*::*:****:**:*:* **.:. :: : : ** *:::. **::** :*::::*** ::**:.* : :.:* . * ** :. **:*: . : *. .: :. * :. : .* * :: *::..* ...::: : *. ..**:.** : .: :* :.. :* *.**.:.* *.: ***.*: :.::.: :* :. ::: : ** .:*:*. :*: :.:.... ****. : : ... .*::* .* ..: *.:: : .: . . : * : :: *: ** : : . : ::. . :** : :::*: : .: * *.: **:. : : : * : ", "identical_positions": 379, "similar_positions": 746, "identity": "13.9%" }, { "cls_id": "homologset.agr.HGNC:32418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4K7J2-1", "uniprot_id": "RBP2_DROME", "id": "A0A0B4K7J2-1", "name": "E3 SUMO-protein ligase RanBP2", "aln": "MFTTRKEVDAHVHKMLGKLQPGRERDIKGLAVARLYMKVQEYPKAIEYLNGYLRVRDDAVGHNMIATCYSRLNPPDVTEALQHYQRSIQIDPRQSEVVIDACELLVKENNASITECARYWLDQANSLDLSGNKQVFNLRMRVNLADSNGERDDTSGGDGEQNTLEILMYKELQARPQDVNIRIQLLRSYVEKMKIDQAFN--YALKTELESKNCTSQSNEWYEQIWMVLFKIEMAKDVKKNWRFWHFALHTLDR-LVQLSLEGSGLADSSKQLFRLDQYLFKFSTSIERSGDAPQRDLHQACIDHFTGQLLLHAVTLIFKREVLANKNKWMSTLRSALPLLLLGYQVRPIDDSSTNQWIKHCDAEQKQLIQMWRPQGAFRCAQLGRTLLGCLDRSQMEIKNDRENAEFDENKNSGNSMPGLFADSEELLASAHQQCLDKSWRSQIYQQLFTHAEHKLKDTSSHLVRNLRLQLPLFEWPNLAHIENYELQALVLPPHSLAQHVYLALGTDPNKLGDAPRVVFYEGFQRDVKQN--LNYCGQDSISQVDVDLYLYATTIQTRRKLQIQREVYDSSNLGNRNAAARPHMMPFANLVGQLGAPEQSNWWDLVVRLNSNQLITEGNRAEQRAQLQHGLEAVRGVNGPKADAIIIFQLGKILNSRSDRSSLEARIDTLYRQGFSILRHQHNQQMESYVRVFKYGSAGSTAAWQDLQSLAEEAVTYFSEKMFRIGQYEQFLDEVRGLHLPMAYFLQSEACHHLEESSKLPRTSRDRYSERRRECLQKTQKLIKNDDKHPLIAAMHRHQQDRNSRGIDNSFGSPDVHNNSSAYEDAEDDFYSHAAFSANRSRRQLEVTPVTPIVMAQPSQEMEQAVKQISKSLCVLKDDVSVGMEAMRQDIKVLTEKFTGLEDLLKKIKISSRDTPTRDVDPAAALGLDDLFIIEDALAEHQQQQQHQQQQSHNQGAIHPVVPNPYTSGFYNGMPNTPSAQERFLQGPYGSPMFNQNQMYNYYAAQAQAQAQAQFLRTPPAPGSIPPPNMFGPRNPNFGLPSMFPPPTVPSVAPYIDAMGNFTQPPPSLIPPPAQPAAPPAPLNILESKPVVALPTPGFFNTTTPVFGASPIQVPQSKPLTVPTVPIPSTAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQPTLSVTIPAQHIKPSLVQAPEQPAQSAQPAQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEEAEQNQSGATDPNKTLPQDTSADDYDPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFKSFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSAAPATSAPASATPFASFSFTPNGSSGFGTSTASPFGNLSFGTASAVGSGNNTTLFTTALIKDNTVQGKTLQQESQLNKSNSSDAEEEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNKVRLLMRREQVHKLCCNQRLLPETKFTYATNCKAAVTWGAQDYSDEELTTALLAVRFKSQDICQQFLEAVQKAQQSIGNEPKKEEVPSAAGEKEKPIKGFGDAFKPKAGSWNCQACYTNNGQDQLYCLACQEPKDATVPPKQSGLDQGNALNLTTSSSNKFSFGFASSATLPATGGFSFGGATQPKEKPAVAVVTASASAPTSVQTAALGFGKSSMTSGFGDAFKPAVGSWSCSACYVNNPGESLYCSACDAPKNDTVPQKEKSLGSGLNLPPTSKFSFGFGAAAAGDKDQAGDGATFNFAAMPAAVAPTTSIGSSSFTFSMTKPKPDQQQPNSTAAKEDEDNDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESD--WKERGLGDVKILRHRQTKKLRVVMRREQVFKICLNHVLNENVVYR--EKTETSWMFAVHDFSEGESVLERFTLRFKNKEVAQGFMEAIKNALNETAKPIEDSPVVGSVSQSTEANKPSQKNDGAAKSRGGESEVLDVGKTSSVRPTTHEVIPPLPMTLPLLTLPQPLAKPNDYQTPATILFKGSSLSRNNSSASEASKTPSSAFIFGSTDKSEPGKDAGPLANLQKLASGEGQGNVLGSIFRSGSSNENSSDGSVKFFFGGGNKAAEQQKKDSSESVFGGNKADSQSPATQEAPKLAFGGIAAPVFGDANPFGGHKVNLQKSDGKEEPKSIIGGTPLLFGGSNAFGIPKIETQSPAKDFVFGSAPAFGQMATFSFTAAKNEKEKDITSNNTTDLKAEGKEKKELVPETTSTFADLAKTGSTFADLASNPGGTFADLANKTGNDFANLSANSQGTTVGFNKSAGGGFYNLTHQNAFKNFESPQATEECDDDGDATTDDNYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVLEHPELQTFRLIMRQEQIHKLVLNMNISASLQMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTVNSCIKRAKALQGDEENKNDDAPEEQASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O14715-1", "uniprot_id": "RGPD8_HUMAN", "id": "O14715-1", "name": "RANBP2-like and GRIP domain-containing protein 8", "aln": "MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDPKAHRFLGLLYELEEN-TEKAVECYRRSVELNPTQKDLVLKIAELLCKN--DVTDGRAKYWVERAAKLFP-GSPAIYKLKEQLLDCE----------GEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKRLKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELS------ATFLEMKGHFYMYAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVP-------------------------RPKIKLREGKAGQNLLEMMACDRLSQ--------------SGHMLLSLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPK----DTSFLGSDDIGKIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSS--------YQPLCLPFP-VCKQLCTERQKSWWDAVCTLIHRKAVP-GNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSG-------------------------------------------------------------------LNSFYGQLEYIGRSVHYWKKVLPLLKIIKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAVNGN-----IEDAVTAFESIKSVVSYWNLALIFHRKAEDIEN------------DALSPEEQEECRNYLTKTRDYLIKIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGP---------------LYKNGSLRNADSEIKHSTPS-----------PTKYSLSPSKSYKYSPETPPRWTE--------DRNSLLNMICQQVEAIKKEMQELKLNSSKSASR-----------------------------------HRWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAAN-----------------------------------------------------------------------------VTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLENDTG-------------------------------------------------------------------------LQAQDIRGRKKGRGVIFGQTSSTFTFADVAKSTSGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFQFGKKDLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDS-------DDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVN-GKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIP--LQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTN-----------------------------DQTKVTEEENKGSGTGVAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVHASP-----------------------------------------------------------LASSPVRKNLFRFDESTTG--------------------------SNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPRES-----------------------------------------------------------------------------------------------------------------PCGKIAVAVLEEITRERTDVIQGDD-----------------VADAASEVEVSSTSETTTKAVVSPPKFVF--------------------------------------------VSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKK----------CELSKN---------------SDIEQSSDSKVKNLSASFPTEES-----------SINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTKSADHLNGLLREIEATN------AVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPE-------------------------------------------------EKGKLAAVAQDEEENPSRSSG------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: :*: :* .:** . *::.:**: .*:** :.:** * :*: *:.*:: : : .*: . :*:: *:**::::* *.::*:. .*** *: *:**:::* .* *. :::*: :: .: *:. *.* *: .** .**:**::.*:*:. * .. ::.:*. : : :: :.. . .. : : * .:: :. *.:** : * *: *:*. .: :. : * :*. * . .:*: ..: . * : .:.*:: ::* :*::* .*: :* : . * *:.:** **: :* .: *:.** : .::. **: : .* ..:::* .. : :* :* :*: **: . * .: :: . : .: *:* .: .*:: *: ** : .:*.* :. . * : : *:* ::. *: . :**. :*::::* ... :: :*: : : :.** :* :**. : ** : .*..*** * * .: :. ** *: * :** ::::*. : :. ::.: .* *:. .. :.* .::. : .: *: : . :: :...:*.. :.. : :* :: : ::* * :* :. : : *:::. : : :. :* : *: :* * : .: .:* .: :.: . * : ** . .:..::: * . *:.:::::: *.. * : :.:* : :.: :*. . *. *: . :. :*.: *: : ::*.: * . *.:* : . :. * . : *.. * : * . .. .: : .** . *..: : :*.:.:. : * :: :*.:. .:. *.: :*:.:.*: :* .: :. :* : :* : ... : ::* ::*..: * . :. * :.* . * . **: .:. . *:*:: . : ::: . ::::.: *::.* :* **: :*: **:*****.*.**:.: .**:*:* *..:********:*:*::..: .*:*:******* *:*.*: : . ::. :... * *.*.*:** : . **.:**: ::.::* : .::.*: : : * :.* :. :. * : * : *:* : :: ** : ::* ...: . *.*.:: . . . . *.* :: : : . *..:* *: * .*. * * *. :::* .. **. ::: .*. : :* :: :::. ***.:. **.**:**** ::*.:***:*:::: *:*::** ::. *****:**:***:: :.*::*:****:**:*:* ** :. :: : : ** *:::. **::** :*::::*** ::**:.* : :.:* . * :* *. * . *: ..*: ** .* *. :. :..* *::..* ...::: : *. ..**:.* : .: :* :.. :* *.**.:.* *.: ***.*. :.::.: :* :. ::: : ** .:*:*. :*: :.:.... ****. .:.: : *.* * .: . . . * : * ** .*. :: *: ** : : . : ::. . **: : :::*: : .: * *.: **:. . * * . *.:*** . .: ", "identical_positions": 384, "similar_positions": 739, "identity": "14.08%" }, { "cls_id": "homologset.agr.HGNC:32419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4K7J2-1", "uniprot_id": "RBP2_DROME", "id": "A0A0B4K7J2-1", "name": "E3 SUMO-protein ligase RanBP2", "aln": "MFTTRKEVDAHVHKMLGKLQPGRERDIKGLAVARLYMKVQEYPKAIEYLNGYLRVRDDAVGHNMIATCYSRLNPPDVTEALQHYQRSIQIDPRQSEVVIDACELLVKENNASITECARYWLDQANSLDLSGNKQVFNLRMRVNLADSNGERDDTSGGDGEQNTLEILMYKELQARPQDVNIRIQLLRSYVEKMKIDQAFN--YALKTELESKNCTSQSNEWYEQIWMVLFKIEMAKDVKKNWRFWHFALHTLDR-LVQLSLEGSGLADSSKQLFRLDQYLFKFSTSIERSGDAPQRDLHQACIDHFTGQLLLHAVTLIFKREVLANKNKWMSTLRSALPLLLLGYQVRPIDDSSTNQWIKHCDAEQKQLIQMWRPQGAFRCAQLGRTLLGCLDRSQMEIKNDRENAEFDENKNSGNSMPGLFADSEELLASAHQQCLDKSWRSQIYQQLFTHAEHKLKDTSSHLVRNLRLQLPLFEWPNLAHIENYELQALVLPPHSLAQHVYLALGTDPNKLGDAPRVVFYEGFQRDVKQN--LNYCGQDSISQVDVDLYLYATTIQTRRKLQIQREVYDSSNLGNRNAAARPHMMPFANLVGQLGAPEQSNWWDLVVRLNSNQLITEGNRAEQRAQLQHGLEAVRGVNGPKADAIIIFQLGKILNSRSDRSSLEARIDTLYRQGFSILRHQHNQQMESYVRVFKYGSAGSTAAWQDLQSLAEEAVTYFSEKMFRIGQYEQFLDEVRGLHLPMAYFLQSEACHHLEESSKLPRTSRDRYSERRRECLQKTQKLIKNDDKHPLIAAMHRHQQDRNSRGIDNSFGSPDVHNNSSAYEDAEDDFYSHAAFSANRSRRQLEVTPVTPIVMAQPSQEMEQAVKQISKSLCVLKDDVSVGMEAMRQDIKVLTEKFTGLEDLLKKIKISSRDTPTRDVDPAAALGLDDLFIIEDALAEHQQQQQHQQQQSHNQGAIHPVVPNPYTSGFYNGMPNTPSAQERFLQGPYGSPMFNQNQMYNYYAAQAQAQAQAQFLRTPPAPGSIPPPNMFGPRNPNFGLPSMFPPPTVPSVAPYIDAMGNFTQPPPSLIPPPAQPAAPPAPLNILESKPVVALPTPGFFNTTTPVFGASPIQVPQSKPLTVPTVPIPSTAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQPTLSVTIPAQHIKPSLVQAPEQPAQSAQPAQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEEAEQNQSGATDPNKTLPQDTSADDYDPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFKSFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSAAPATSAPASATPFASFSFTPNGSSGFGTSTASPFGNLSFGTASAVGSGNNTTLFTTALIKDNTVQGKTLQQESQLNKSNSSDAEEEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNKVRLLMRREQVHKLCCNQRLLPETKFTYATNCKAAVTWGAQDYSDEELTTALLAVRFKSQDICQQFLEAVQKAQQSIGNEPKKEEVPSAAGEKEKPIKGFGDAFKPKAGSWNCQACYTNNGQDQLYCLACQEPKDATVPPKQSGLDQGNALNLTTSSSNKFSFGFASSATLPATGGFSFGGATQPKEKPAVAVVTASASAPTSVQTAALGFGKSSMTSGFGDAFKPAVGSWSCSACYVNNPGESLYCSACDAPKNDTVPQKEKSLGSGLNLPPTSKFSFGFGAAAAGDKDQAGDGATFNFAAMPAAVAPTTSIGSSSFTFSMTKPKPDQQQPNSTAAKEDEDNDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESD--WKERGLGDVKILRHRQTKKLRVVMRREQVFKICLNHVLNENVVYR--EKTETSWMFAVHDFSEGESVLERFTLRFKNKEVAQGFMEAIKNALNETAKPIEDSPVVGSVSQSTEANKPSQKNDGAAKSRGGESEVLDVGKTSSVRPTTHEVIPPLPMTLPLLTLPQPLAKPNDYQTPATILFKGSSLSRNNSSASEASKTPSSAFIFGSTDKSEPGKDAGPLANLQKLASGEGQGNVLGSIFRSGSSNENSSDGSVKFFFGGGNKAAEQQKKDSSESVFGGNKADSQSPATQEAPKLAFGGIAAPVFGDANPFGGHKVNLQKSDGKEEPKSIIGGTPLLFGGSNAFGIPKIETQSPAKDFVFGSAPAFGQMATFSFTAAKNEKEKDITSNNTTDLKAEGKEKKELVPETTSTFADLAKTGSTFADLASNPGGTFADLANKTGNDFANLSANSQGTTVGFNKSAGGGFYNLTHQNAFKNFESPQATEECDDDGDATTDDNYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVLEHPELQTFRLIMRQEQIHKLVLNMNISASLQMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTVNSCIKRAKALQGDEENKNDDAPEEQASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O14715-1", "uniprot_id": "RGPD8_HUMAN", "id": "O14715-1", "name": "RANBP2-like and GRIP domain-containing protein 8", "aln": "MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDPKAHRFLGLLYELEEN-TEKAVECYRRSVELNPTQKDLVLKIAELLCKN--DVTDGRAKYWVERAAKLFP-GSPAIYKLKEQLLDCE----------GEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKRLKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELS------ATFLEMKGHFYMYAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVP-------------------------RPKIKLREGKAGQNLLEMMACDRLSQ--------------SGHMLLSLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPK----DTSFLGSDDIGKIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSS--------YQPLCLPFP-VCKQLCTERQKSWWDAVCTLIHRKAVP-GNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSG-------------------------------------------------------------------LNSFYGQLEYIGRSVHYWKKVLPLLKIIKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAVNGN-----IEDAVTAFESIKSVVSYWNLALIFHRKAEDIEN------------DALSPEEQEECRNYLTKTRDYLIKIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGP---------------LYKNGSLRNADSEIKHSTPS-----------PTKYSLSPSKSYKYSPETPPRWTE--------DRNSLLNMICQQVEAIKKEMQELKLNSSKSASR-----------------------------------HRWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAAN-----------------------------------------------------------------------------VTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLENDTG-------------------------------------------------------------------------LQAQDIRGRKKGRGVIFGQTSSTFTFADVAKSTSGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFQFGKKDLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDS-------DDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVN-GKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIP--LQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTN-----------------------------DQTKVTEEENKGSGTGVAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVHASP-----------------------------------------------------------LASSPVRKNLFRFDESTTG--------------------------SNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPRES-----------------------------------------------------------------------------------------------------------------PCGKIAVAVLEEITRERTDVIQGDD-----------------VADAASEVEVSSTSETTTKAVVSPPKFVF--------------------------------------------VSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKK----------CELSKN---------------SDIEQSSDSKVKNLSASFPTEES-----------SINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTKSADHLNGLLREIEATN------AVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPE-------------------------------------------------EKGKLAAVAQDEEENPSRSSG------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: :*: :* .:** . *::.:**: .*:** :.:** * :*: *:.*:: : : .*: . :*:: *:**::::* *.::*:. .*** *: *:**:::* .* *. :::*: :: .: *:. *.* *: .** .**:**::.*:*:. * .. ::.:*. : : :: :.. . .. : : * .:: :. *.:** : * *: *:*. .: :. : * :*. * . .:*: ..: . * : .:.*:: ::* :*::* .*: :* : . * *:.:** **: :* .: *:.** : .::. **: : .* ..:::* .. : :* :* :*: **: . * .: :: . : .: *:* .: .*:: *: ** : .:*.* :. . * : : *:* ::. *: . :**. :*::::* ... :: :*: : : :.** :* :**. : ** : .*..*** * * .: :. ** *: * :** ::::*. : :. ::.: .* *:. .. :.* .::. : .: *: : . :: :...:*.. :.. : :* :: : ::* * :* :. : : *:::. : : :. :* : *: :* * : .: .:* .: :.: . * : ** . .:..::: * . *:.:::::: *.. * : :.:* : :.: :*. . *. *: . :. :*.: *: : ::*.: * . *.:* : . :. * . : *.. * : * . .. .: : .** . *..: : :*.:.:. : * :: :*.:. .:. *.: :*:.:.*: :* .: :. :* : :* : ... : ::* ::*..: * . :. * :.* . * . **: .:. . *:*:: . : ::: . ::::.: *::.* :* **: :*: **:*****.*.**:.: .**:*:* *..:********:*:*::..: .*:*:******* *:*.*: : . ::. :... * *.*.*:** : . **.:**: ::.::* : .::.*: : : * :.* :. :. * : * : *:* : :: ** : ::* ...: . *.*.:: . . . . *.* :: : : . *..:* *: * .*. * * *. :::* .. **. ::: .*. : :* :: :::. ***.:. **.**:**** ::*.:***:*:::: *:*::** ::. *****:**:***:: :.*::*:****:**:*:* ** :. :: : : ** *:::. **::** :*::::*** ::**:.* : :.:* . * :* *. * . *: ..*: ** .* *. :. :..* *::..* ...::: : *. ..**:.* : .: :* :.. :* *.**.:.* *.: ***.*. :.::.: :* :. ::: : ** .:*:*. :*: :.:.... ****. .:.: : *.* * .: . . . * : * ** .*. :: *: ** : : . : ::. . **: : :::*: : .: * *.: **:. . * * . *.:*** . .: ", "identical_positions": 384, "similar_positions": 739, "identity": "14.08%" }, { "cls_id": "homologset.agr.HGNC:3242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z6-1", "uniprot_id": "EHD1_RAT", "id": "Q641Z6-1", "name": "EH domain-containing protein 1", "aln": "MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQAVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSKRRHE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVK4-1", "uniprot_id": "EHD1_MOUSE", "id": "Q9WVK4-1", "name": "EH domain-containing protein 1", "aln": "MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQAVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSKRRHE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4M9-1", "uniprot_id": "EHD1_HUMAN", "id": "Q9H4M9-1", "name": "EH domain-containing protein 1", "aln": "MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************************************************************************************************************************************************************************************************************************************************************************************.*********************************************************.*********************************************************************************************************************:********", "identical_positions": 531, "similar_positions": 3, "identity": "99.44%" }, { "cls_id": "homologset.agr.HGNC:32422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z960-1", "uniprot_id": "D3Z960_RAT", "id": "D3Z960-1", "name": "", "aln": "MNVSFLNHSGLEEVG---GDARATLGNRSHGLG-TWLDCCPG-GAPLTASDG-VPAGLAPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLMQERRPSKDVGAAILGLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3URD2-1", "uniprot_id": "RPRML_MOUSE", "id": "Q3URD2-1", "name": "Reprimo-like protein", "aln": "MNVSFLNHSGLEEVG---GDARATLGNRSHGLG-TWLDCCPG-GAPLTASDG-VPAGLAPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLMQERRPSKDVGAAILGLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4K4-1", "uniprot_id": "RPRML_HUMAN", "id": "Q8N4K4-1", "name": "Reprimo-like protein", "aln": "MNATFLNHSGLEEVDGVGGGAGAALGNRTHGLG-TWLGCCPG-GAPLAASDG-VPAGLAPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLVQERRPSKDVGAAILGLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PLA0-1", "uniprot_id": "RPRML_DANRE", "id": "A5PLA0-1", "name": "Reprimo-like protein", "aln": "MNGTFFNHT-VFTHG--------VLLNRSQELAGTLVDCCTGNGSEVTANDGGGSLVLAQDERKLFVTRVVQIAVLCVLSLTVMFGIFFLGCNLMIKSESMINFLVKDRRSSKDVEAVMIGLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*:**: : . .* **:: *. * :.**.* *: ::*.** . ** ***.*:*:**.************:**:*******:**********:::**.**** *.::** ", "identical_positions": 66, "similar_positions": 31, "identity": "53.66%" }, { "cls_id": "homologset.agr.HGNC:32423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGP9-1", "uniprot_id": "DRS7C_RAT", "id": "D3ZGP9-1", "name": "Dehydrogenase/reductase SDR family member 7C", "aln": "MGIMAVLMLPL----------------LLLGVSGLLFIYQEASRLWSKSAVQNKVVVITDALSGLGKECARVFNAGGARLVLCGKNWEGLESLYAALTSVADPSK-TFTPKLVLLDLSDISCVEDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITFTKVLLPNMISRRTGQIVLVNNIQAKFGIPFRTAYAASKHAVMGFFDCLRAEVEEYDVVVSTVSPTFIRS------------YQAYPEQRNWGSSICKFFCRKL-TYGVHPVEVAEEVMRTVRRKKQEVFMANPVPKAAVFIRTFFPELFFAVVACGVKEKLSVPEEG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHS7-1", "uniprot_id": "DRS7C_MOUSE", "id": "Q8CHS7-1", "name": "Dehydrogenase/reductase SDR family member 7C", "aln": "MGLMAVLMLPL----------------LLLGISGLLFIYQEASRLWSKSAVQNKVVVITDAISGLGKECARVFHAGGARLVLCGKNWEGLESLYATLTSVADPSK-TFTPKLVLLDLSDISCVQDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKVLLPNMISRRTGQIVLVNNIQAKFGIPFRTAYAASKHAVMGFFDCLRAEVEEYDVVVSTVSPTFIRS------------YRASPEQRNWETSICKFFCRKL-AYGVHPVEVAEEVMRTVRRKKQEVFMANPVPKAAVFIRTFFPEFFFAVVACGVKEKLNVPEEG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNS2-1", "uniprot_id": "DRS7C_HUMAN", "id": "A6NNS2-1", "name": "Dehydrogenase/reductase SDR family member 7C", "aln": "MGVMAMLMLPL----------------LLLGISGLLFIYQEVSRLWSKSAVQNKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLDLSDISCVPDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPNMISRRTGQIVLVNNIQGKFGIPFRTTYAASKHAALGFFDCLRAEVEEYDVVISTVSPTFIRS------------YHVYPEQGNWEASIWKFFFRKL-TYGVHPVEVAEEVMRTVRRKKQEVFMANPIPKAAVYVRTFFPEFFFAVVACGVKEKLNVPEEG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E5C5-1", "uniprot_id": "DS7CA_DANRE", "id": "A8E5C5-1", "name": "Dehydrogenase/reductase SDR family member 7C-A", "aln": "MAVPSVMVLPL----------------LIVVFAGVYYVYNEVMRFMSKSVVRNKVVVITDAVSGMGSECARLFHAGGARLVLCGPSWDKLESLYDSLCSGSDPSQ-TFTPKLVLLDFSDMENISDVVSEICECYGCVDVLICNSSMKVKAPVQNLSLEMDKTIMDVNYFGPITLAKGVLPLMITRRTGQFVLVNSIQGKLALPFRTCYAASKHAVQAFFDCLRAEVEEFGISVSTISHTFINAGAENATPTEATPITATPTKATPTNPIWAYVCSKLNTHGVSPQILAQEIVRSVNRQSREVFLAHPVPTVALYIRALMPGCFFSVVSAGVRDGAMAEQLK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5BL28-1", "uniprot_id": "DS7CB_DANRE", "id": "Q5BL28-1", "name": "Dehydrogenase/reductase SDR family member 7C-B", "aln": "MGMSDIMWLDVSWAW--------LVLTAVLLAAAVFYLYTLILSHLAKTTVRNKVVLITDSLSTVGNECAKLFHAGGARLILCGSNWEKLEALAEQLTSQSDPTL-TFPPKLVELDFSDMESVPEVISEILECFCCLDVLVFNSSMKLKAPVHSLSLQMDRLLMDVNYFGPITLVKGFLPSLISRRSGHILLVNSIQGKLAMPFRTTYAASKHAVQAFFECLRAEVQEYGITVSTINHTFIKT------------SSSIPKDEITARSMKTDHRQTP--LGVSPKDVATELLRTLSSKKKEILMARWVPKAALYVRSLFPNLFFAIMAARVSNTVAETPDD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y140-1", "uniprot_id": "DHRS7_DROME", "id": "Q9Y140-1", "name": "Dehydrogenase/reductase SDR family protein 7-like", "aln": "MKVQDMDKCAPSSDWNVLYWVLGTVLMPVALPLAIINIWQRFQAQKFRNQLPGKVVLITGASSGLGESLAHVFYRAGCRVILAARRTQELERVKKDLLALDVDPA--YPPTVLPLDLAELNSIPEFVTRVLAVYNQVDILINNGGISVRADVASTAVDVDLKVMVVNYFGSVALTKALLPSMVKRGSGHICFISSVQGKFAIPQRAAYSASKHAMQAFADSLRAEVANKNINVSCVSPGYIRT--------------QLSLNALTGSGSSYGKVDETTAKGMSPDKLAERILQCILRKEPDIIVSDVQAKIAYYLRHLCPSLYFWIMAKRAVKLENAEKKST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : : .: :: :. : .***:**.: * :*.. *::* .*.*::*.. : ** : * : . :.*.:: **::::. : :. ..: : :*:*: *..:.::. . . ::::* :* .****.:::.* .** ::.* :*:: ::..:*.*:.:* *: *:***** .* :.***** : .: :* :. :*.: . . *: * :* .::: : :. ::::: .. * ::* : * :* ::: . . ", "identical_positions": 58, "similar_positions": 126, "identity": "16.96%" }, { "cls_id": "homologset.agr.HGNC:32427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M5B9-1", "uniprot_id": "F1M5B9_RAT", "id": "F1M5B9-1", "name": "", "aln": "ASVLRAMTLPYVMTPLGFGFCSPSLLLTGQVLLVVTQADPIAEWVQNPVRLTSEPWVPTKLWSLHHSDQPPKPLKVHTSQAGARAFDYQGSSAPSQVFSPPQELKDSFLSFQAVDTSTEPHPESDQFTVSYQH--------LANQMTPPRKLQENILKPKGDQNQSLAKAIVRTTKQFTKSQLQKKTVENEYRESNLNEAYSNGLPLQPQVNREEPPEPSELIEQPEYLLGAQTRDSENL------HMVQESPDRLPLLPEEHE----KEEPVQQHFASGKVVVLKRP---DMNVPSANGNEAHHSNLANVTVKPVD-----LEI---------------------------------------LVQFSEEPDEIESSLTQQEATAPNPELSEELEPSLVRQEALGESLELPEDLETSGSQLEVPALPTKPSEEVS----------------PPIEEEA---TPEPSVPRIIETPAATASHLSQDQVHHYTLPLITAK-------LTSKPFKEAKTSPVQKETSTRTLGSRMKAGHYGLEEQP-DEPSESSGEDESPE------------------------------------SPFLE-------------------------------------------------------------------------APNKAYYYHLPNITI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIQHSNPTEVTVQPLDLGFTLTPQLTPE-ELLQTMPETTTQITETPTEVVAPGLLYQKMTVPTPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QAEHSTTPVMTTG----------------------------------------ELSQT----------------------------------------------------TQDSTTQPIETTKGAVAQAPVYQEVTLATSSQNAVEYPTFPIITFQLLNLGLTK---HLEPAREAHD------------------------------------------------FTVLKETTILPLKNPQVTLPEQVH--TQHSHQSEITLLPLNPELSMSPQPTP----------------------------------------EVELSQTVQETK-----------------------------------------PLDLELALSSEP---------------------------------------------------------TTSHEITVS-PPQYHQMTLSEPS--SIQHPNLTDVTAQPMTLEFSVIPSPN----------------------------------------LNVETSPHIQETFPEAEPPPEEVTAKAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTDVCDFCLCENHTLLCVHLSPMQKLRQVPVPRPNTYKGTLTVL------------------------ILSKNHLTELHKDSFEGLLSLQVLDLSCNKIHYIERRTFESLPFLKYISLECNLLTELSFGTFQAWHGMQFLQQLILNRNPLTVVEDPFLFKLPTLKYLDLGATQVQLTTVENILMMTLELEHLILPSNMACCLCEFKVDIEVICKTIKLHCNTGCYTGWTNTTHCPTAS-IRNPEGTFMKVLLARKENTRAELTIEPERVHSDRNDPSSSGLMNEQLDFNDESDVISALNYILPYFSEGNLEDVVSTLLPFIKLFL---------------------------------------------------------------------------------------------AEIEKAERRLLSMNRAPEGTGSLRKRHFKEVRVKSLGSKQSAQTPVENSAKDRHLWRTAPRTGSPASVELQQLHLEQKPRVLVENSFPSEPLLAKDHGKELSSSL--GPALVDKAPAPKSLPEFLDRRKDLSYTIFVLESANANVKRAKGSNPNLQ------------------PEERRGNLRKKKSHFQLIAKRPVAASSAVRSLVNSPAQGVLSSLGNLSYPERPFSESYTASQPSTEKPLEENQAATDNVKENILKLTVTVPAEIKSENKPREKPTTGSIVSTSS---LVPTVQQTSKPQSDFTVGSDTHAPSTEAAHPSLMSPGEQFESHLNQQLRPLIPNNDVRRLISHVIRTLKMDCSDTRVQLACAKLISRTGLLMKLLSEQQDFKLSRTDWDTDQWKTETYINESTEAQGEQKGLEPSQVR-TAPGQG--------------ASVSPISSAEMTWGSHSRSSASLITLAQPRQR-----FPLSDGFFWIRCPLWLRDMYRPLHDTRKKNMAQDLQDKESSGEEEIFNKDVPG---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AWG4-1", "uniprot_id": "B1AWG4_MOUSE", "id": "B1AWG4-1", "name": "", "aln": "-------------------MFSPPRELKDSFLSFQAMDTSVASHPE------SDQFTVPHQHLAKQMTPPRKPLESVPKLNGD-----QNQSPQFKSISSLDQAADDQL-FEIPDPPLDSENSS-----------------ITKFIASPQSLQKELVQHR-----PLAKEVVGTTKQFAKSQLQKKTVVDEYRDPNMNEAYSKSLPLQSQANRE---GPSEKIEHPEYPLEAQTQESENL------DMVHESPEYLPVLPEEDEPSVPKENPVQHHFASGKAAALKHP---DRNAPSPKRNEARHSKLPNVTVKPED-----LEVTVMSEADKETQQTLSQQQAPGHLPESPKEVEPSSTPQDTLEQFSGGPEEIETLLTHQEAAAPNPELPEELGPSLVQQEVLSESLELPKDLEASGSQLEVPARRTKPPEEVN----------------PPTEQEARIPTPEPSMPNIIEIPAATVSHHNQDQVHHYTLPTITVQPADVEVTITSKPFKEAEISPVQEETQTP--GPPRKVGHYSLEQQP-AVSSESSGEVGSLERYLGFLTQPPEEEEEEEEEEDEESSLTQEDIPSQHPSPILEGEPSPIELQQPIRPSESPEEVGLGPENQSEVLVKPAELPEEVKSPVEQEAPLQAPESHFETIVDTPPIHEVQPAPNKAHHHHWPNVTVRPVDLELAITSEPTRETESSLAQQESSVHPSEYTEERDSFRYKQEQLAQPSKLEILIHTSEHHHLTSSPSAHHRTHHSSSPTTMVRPPDVQLTIAQNPTAEVEPPPAL--------HEVVGKPIAISDKGVNTSTHHTHPAVTPEPSEEVELLSNQEEAPVQSAEPVEYEKSSLSQQKSTDKNPELLEEGGLSSAQQETLVNPPVFPNEMIVQPSAHYEATGPPLIQTQLHPPASYNVTAKPPELTNEVETSSQQGVEPSNDQQEEVTSQYPMPPETHQDSPVYQWVLTQPAKLPEEVSSGQQGNLSPPLKHPPGVQFIPFQQELPDQHLEPPKEGFFLSPVADSVLFSPEDLEAMFRYETSVLHKPTVIHLNQAVSSMEVESLKVPTEQVEYSQVHFEYPSYTPAFPETQFSQEKSITQEADLHEDIYPFPTQHRGLYLPPDSFMGAEPSVTQHLSLSQLEDLAENVGPSLVLQLTPAQASEPPKEIVFSPTQQVVPNQLPESLNNIVTQL-LTQQIIGPTPGQIQEEYPTEHTVSFQALDLEFTITSQYTPEANHTTEPK----------RTPPPTYPQVTFSYPSEVTVQPLDLGLTISPQPTPE-ELPQAIPEITTQITEPPREVVAPAPLYQKMTVPTPGQDQVEYPIPPAISFQPLDLELTKNSEPTRETQQPTATMKTIVPSPEHLQDYISYVAEVTVQPLDLGLTISPQSAPEELPQPMPEITTQITEPPREVVAPAPLYQKMTVPTPGQDGVEYPILTAVSFQPLDQKLTISSEPTREVHHSTTPKETTVPPPKLSQVTLPREFHIQNLYLSEAAVQPVDLGLTITPQPNSEELPQTISEITTQITEPPKELVAPLYQE---VTVPTPGQDQAEYPTLPVASFQPLDPELTISSEPT-----------------------------------------------------RETEQPTAEVTVQSLDLELTISLQSTPEELLQTMPEITTQITEPPGEVVTPLYQEVTVSTPSLAQTEYPTSHIVSFQPLDLELTKNSEPTRETQQPTATMKTIVPSPEHLQDYISYVAEVTVQPLNLGLTISPQSAPEELPQP-------MPEITTQITEPPREVVAPAPLYQKMTIPTPGQDQDAHSTTLQPVGLELTETSDSTREAEHYTTLVMTTVSSPKYSLPEQVLLQHLNPAEVTVQALDLGLTITPQPDTEKELSQT----------------------------------------------------TQESTTQLIDPPKEAVAQAPVYQEVTLATPSQDAFENPTLPIITFRLLDP-------DPEPAREADN------------------------------------------------LATLKETTIPPPKYPPVTLPEQVH--TQHPHPSEVTFQPLDMELSMSPQPTP----------------------------------------EVELSQAEQETKTQPSYSAKEVVTPKPGYPEVTVPTPDQDKTEDQTLTAALFQPLDLELTRSSEP---------------------------------------------------------TTPHKSTVVSLPQYYQTTLSGEV--YTQHPNLTEVTDQPLNLELTVIPSPN----------------------------------------LNVETSPHIQEMLPEPERPHEEVTAKAPMFYEITPIQDQTPHLVSPKVTDQHIKVEHDIPTISS------------------------------------------------------------------------VENGLLAATYSSTALPLTHHEMVLLSEDQVQVLHGNPTQVTIHPSHPEFSLASPPATMVKRSAPVQS---------------TESSKETAAQSPVHLKETVLMIAHGQSQHLNSETTQPEVPATTHPETTQSTASPTTHSETTHSTASPTTHPDTTQSTASPTTHPETTQSTASPTTHSETTQSTTSPTTHPETTQSTASPTTHPDTTQSTASPTIHPDTTQYTTSPTTHPETTQYTDLTTMPPPSTHYEVVLSQSSQVQTQQPKPSEVTMWPSPTSQQSSTTPQSVILASPFATMLETTAQQIPSGIALEPMDLEPTITPYAGNFNTEKDLIFQMKPNVSTSTNICDLCLCENHTLLCSHLSPKRRLHQVPVLRPGTHKGTLTILNFHGNVISYIDKNVWKAYRWAEKLILSENRLTELHKESFEGLLTLQVLDLSCNKIHYIERRTFESLPFLKYINLGCNLLTELNFGTFQAWHGMQFLQQLILNHNPLTVVEDPFLFKLPTLKYLDLGATQVQLTMVENILMMMLELEHLILPSRMACCLCKFKADIEIICKTIKLRCHTGCLT---NTTHCLKAS-IGDPEGAFMKALLARKENSRAELTIEPEKSYADQTNLGSLGLMNEQLDFNDESDVISALNYILPYFSEGNLEDVVSTLLPFIKLLFSNIQNGDNSLGPFQNDTKSLTLKSVPKASKLAYKNKVNKLYFLENLLDEEINEVKEKEKTAMLVHHSGRLDPKFKRQIFEKRWEPARTGKDSLAEIEKAERQLHSMSRVPKETGSIQKRHFKDVSGKSLWSKQSVQTPVESISKDRQLG-------SPPSMELQQLGLEQKPRELVGYSFPSEPLLPKEHRGELSSSP--DLPLLDKAPTTNSLPDFIDRRKDLSYTIYVLESANANVKRAKGSNPSLQ------------------PEARHRNLRKKKSHFQLIAKRP-AASSAVRSLISSSARGVFSSLGDLRYPERPFSELYVAPEPSTKKPLEENRAATDNVEENNLKQIVTTPEETTSENKPPENPTADSNVSTTSN--LISTVQQTSKPQSVFTVGADTHADLTDVAYPSLMSPGEQFESHLNQQLLPLIPNKDVRRLISHVIRTLKMDCSDTRVQMSCAKLISRTGLLMKLLSEQQDFKLSRADWDTDQWKTENYINESTETQGEQRSLEPSQLTKAVPGYGYNNKVILAISVTVIVTVLIIIFCLIEIYSHRTAKEGDEEKSSRYKKNYYKISETQDGFFWLRCPLWLRDMYRPLHDTRKKNMAQDLQDKESSGEEEIFNKDVPREFKRRSSVKSSAEESVVEAPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2A9H6-1", "uniprot_id": "A2A9H6_MOUSE", "id": "A2A9H6-1", "name": "", "aln": "-------------------MLSPLEELTDSLLPFQDPSTLQELNPAS-------EELISHQDLTDKLIPTGKQPGNMLMLSGD-----QNQAP---TLSSEFKSTASLFGDAAKT-----------------------------FIVSPKELKKGLAQHK-----KLAKVVVG------KPQFQKPIMDDYYEDLTMNEPHSYNLPLQSQGNADEVPELLEQVELD--QMETQTQNPE--------NLQQEAPDYFPQSPEEDETLNKKEDPVHHQLYYALPTITGKPVDTQLKITSEPIKEVESSSYEEETPTQTPGPLVG-------------------------------AELFLSQQQQQPGEPSETPEEGESSGIDLESSIQPQEDSEEVGPLPTQQEDLSQHLGPVLEDESSLSELEQPIQLSESPEVVGSDSENQPEASVQPTVFPVVEQEAPFGAPESPIETVVETSPIPEIQPTQNENYQYHLPNVTVIPVDVTLTITLGPIKEVDSFLAQQEFPVHAIEYSNDIEPFLKEEEPPAQTSETPGESQFESQLEVPVQASEYDEELKSSATEQLAQFPENHGVTILPSNLYQTRHSSLSDVTGQPSDLAITITENPIEMGTSVYHDAAATPEEVEFLKTQQG------------VLSQSLEPILYDKPLSQQEDITGISQISEEGEPFPDQQETPEHSLELPTEEIAQPPGHHEVTGLPLGHGQVYSPASQNILTQYPTAPEEDQYSPVGQEVPNQLGEFSVEPSPSQQKLFPVLKPTAAQALKPPRVGNFSLIHNKIPHHSPKPLKNMVTDIPGHKMTVPRPDQDQGEYIISSNGSFQSLDLEVTVTSGITPETMHMLPTRTINPQIYSQVKISHPQHVETQHPNPAKTTVQPLDLELAINLQSTPKENFAQTLQETTTQLTGPLKEVTVQAPEHHEGTIPIPTQDQANYPRSPTVSFQSLDLEPTITPEANGEPYHPTVSQQIIIVHPPKHPLVIYSEQVHTQHPNPTEATAQPLNLELILTSQPTAEGELPQTLQDSTSQIIREPLIEVVALVPIYQEVTVQTPSQDQAEYLTSSTVSFQPLDLELSITPESTREPHLPTVPQQTIIVHPPKNPLVIHSEQVHTQHPNPTEATVQP--------------LDLQPTITPQPTAEGELLQTLQNSTGQITESPTAVAIPVPVYLDMTVPTLSQDQAEYLTSPTVSFQPLDLESTITPEPTREAEHFTTPKNTTAFPPKYTHMTLPQEVSVQHLKPTEGIVPPLNLELTITPQPATEGELSQTVQESTTQITEPHKEIIVPVPVFQEVTVPTPSQDQAEYQTFQHLNLELTSEPTKEAYRSTVSKTTITVNFPKRTQHPN--------PAEATDKPLDLELTIGSSYQSTAEGERFQETTTQISETPKQVVTPVPEYQEVAVSAPIQDQAKYPLLPTVSFHPLDLELTISSEPPREAYPTTTPDQTMVPPQKYPLGIYPGDAHIQHLNPTDITIQPLDLELTVHSQPTTEEEHSQSIRKNTTQITEPVKEVEALAPEGEDVTIPMPILEQTEFPTPNSVSLQSVDQELAILSDLPGWTYHPQKLKEIKRHTPGKIFLHYAEPPMGTVVETPDLFFLKTAKSKPVQETSIYITKSSKEIVARSPEHKEAVLPDPVEGQEKSLNPPNMSLKLLDQERIIPFLPRGLAQEPPNPKETKNHTPGKIFLHHAEHPIGMVAEPPDLFFLKSTKSKPTQKTPTQIKKLRKKVATHTLKYKKGMLTAPVEGQAESVPPPNMSLQPLDQELTISSQLPAWTHNSPNPKESRNHTPAKIFLHYAKPPMGTVVETPDPFFLKTSESKPVQETPTQITKSPKEVAAHTLEYKEGVVLAPVEGQAESVALPNMSLQALDQEFTISPQPPAWTHHPPNPKETKNHTPGKIFLHYAEPPMGMVVEPPDLFLLKTTKYNSVQKNPTQMTKSPKEILAQTPEYKEWVLPVPVEGQAESPTPPNMSLQLLDQEVIIPSLLSPPARDTPNPKETKTHTPGKIFPHYAEPPIRMSVEPPDLFFLRSTKSKSVQETPTQIINSPKDVTAPTREYKKGVLPASVEGQAESSLLPHISLQHLDQELIIPSLPPPQAHNPSNPKETKKYTPGKVFLYYADPPMGMVVEPPDLFFLETTNSKPVQETLTQISESPKEVAAQTLKYKKVVLPAPVQEQDESATSPKMSLQPLDQELTVSSQPPAWNHNPLNPKEIKNYAPGKISLHYAEPPMGTVVEPPDLFLLNTSKSNPGQENPTQITKSPKEVVGQTLDYKEGVLSGPIEGQDESPAPPSMSLQPLDQELTMSSQPPGYTHHSPNAAKTENHTPENNFFPYAEPPMGMVVQPPDLFFLKSTKSNLVQETPSLITKSPKEVAAHTLEYKKRLPPVPVEGQAESPPPPNISLQPLDQELTISSQPPGWTHHPPNPKETKNYTPGKIFLHYADTPLGMIVEPPDLFFLKTTTSEPVQETPSQITKLPKEIIAQTLEYKEGLLPVPFGGEDDSTTPPNVSLQPLDQEIIISFPSLGQAQQPPNVKESKEHQPEEILFHNAEPSMGTVVDLDLFFPKTMESKPVQEAPTQITKSPKEGVVQTLEYKELVVSSIIEGNVKYVTPNVSYRPLDLGLSESSGSTTEVYRSTTLNETTVPSSMHLQVPMPHLHSNFSVTQQPNTMAKHSSIMETPAHPSEIPVETVAQSVEYYPTIVLTSVYIETQHSNLSAIETAHSEVPTTTAPYPQAIYSEVPTTTGLYSEATHFGVSTTTAASPEITHSKAPETTALTPKWPGTTSLSPDQVEKHSSPTVQVLKMESTITPYSENSSTENDLTIEKSAYNYTKICDFCVCENETLLCVHLSPKWRLQQVPVPRPNTYNDTFVILNFKGNDISFIDKNVWKVYRWTEKLILSENHLTELHKESFEGLLSLQVLDLSCNKIRYIERGTFEPLPFLKYMNLGCNLLTELSFGTFQAWHGMQFLQQLILSRNPLAVVEDPYFFKLPALKYLDLGTTQVQLTTVESILIKTLELEHLILPSHMACCLCKFKADIEVICKTIKLHCHTGCLT---NTTRCLEEASIRNPEGAFMKVLQGRTGNTSTELIIEPERGNSDKDYANYSSSMDENIDLNDENDIMSALNYILPYFSEGNMEDIISSMLPFIKLLFSQEQDASNSLGSLQKDPERVPVTNESKTSNVTYKNKLNKHYFLENLLDTDTDEVQKEKKPGRHNAKSKNVGPKFKRQIFEKRWEPARAGEDSLAEIEKAERQLHSMSRVPKGTGSIQKRHFKDVSGKSLWSKQSVQTPVESISKDRQLG-------SPPSMELQQLGLEQKPRELVGYSFPSEPLLPKEHRGELSSSP--DLPLLDKAPTTNSLPDFIDRRKDLSYTIYVLESANANVKRAKGSNPSLQ------------------PEARHRNLRKKKSHFQLIAKRP-AASSAVRSLISSPARGVFSSLGDLRYPERPFSELYVAPEPSTKKPLEENRAATDNVEENILEQIVTMPEETTSKNKSAKNPAADSDIPIPNIPGLIPPVLQTTKPPLHFIFGSDSPNNLEEFAYPSLMTPGEQFESHLNQQLRVLIPNNDVRRLISHVIRTLKMDCSDSQVQLSCAKLISRTGLLMKLLSEQQDFKLSRADWDTDQWKTENYINENTETQSKLKSLGRSQFGKEVSEFSYNNKVTLAISVTVVVIVLIIIFCLIEICSHRTKKGDKEKHKWRKKYK---ERKNKEKYIWIRLPPRLRNILK-LDKKCGHDLRANTQDKLWEVKKRSSVKSSAES------------SEVAETPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60309-1", "uniprot_id": "L37A3_HUMAN", "id": "O60309-1", "name": "Leucine-rich repeat-containing protein 37A3", "aln": "MTSAQCPALACVMSPLR--FWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWS------LAEIIGIIHQLSTPQSQKQTLQNEYS--STDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNH----EVSVQPPGEDQAYYHLPNITVKPAD---------------------------------------------VEVTITSEPTNETESSQAQQETPIQFP---EEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVES---------------SPTQQETPGQPPEH--------HEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP------EPINNENPSPTQQEAAAEHPQTAEEGESS------------------------------------------------------------------LTHQEAPAQTPEFPNVVVAQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETP---TQPPKKVVPQLRVYQGVTNPTPGQD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QAQHPVSPSVTVQ------------------------------------LLDLGLTIT----------------------------------------------------PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT---PKSMTEVEP-------------------------------------------------STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT----------------------------------------EVKPSPTTEETSTQLP---------------------------------------DLGLAIIPEP-------------------------------------------------------------TTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQ-----------------------------------------------SESYTQNKALTAPEEHKASTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLT---NTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEP-SDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLD-VKSLLLPFIKLPTTG----------------------------------------------------------------------------------------NSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLG-------SPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFN--LGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKS-LEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDE-----------------EGFS---------------------------RDSEAPTEEESEALP------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* * ..* . .. . . : . . :. :. : . . ..*:.*:: : :: ..* ** : : * . : .:. .** : : : : * : : .:*::.* : :*:* :* **. :* *. . . :: : * . * .:* *: . *:. **: * .:** : : * * *: : * ::... * . ::*: .** . :.: :: * ::. :: * *. .::* . . :. .*:. * . : : . ..: . :: * **:* :*::*: .* ** :: * . *:. ::: ::* :* ***. . : . :: : : .. ... :* : * .*. . : : . . :.: *: . :. .* . .** . . :: . .. :. *: ** :.. *.. *. * . :** * *: .:* . : . . ..:: * * : . . . :* * : *.:*::* * :. * * .*.* :*:**** .*.*::.*:.:* ** :*.******:******:** ********: *** ***.*****::.* **::***.*************::***.:***:.****::****:*****:*:* * ** ::.**: :***:**:**.******:** .** :***:**:*::.* * ***:* : : :***:***.* .*. : :** ****. :* . . .*::* ***.*: *:*.******* *:: : * :****** *:*:.. :. :.*. . *::*****:* :*: :*..*:.**. :::::* **.. **:* :* *. *. :. ::* :.::* :* . ..:...::**:. ** ***:::* :****:*.*.. * *:* :: *: :: :***::. : . **.:**:.*.::*.:*** :* *.** * ...: :: :: :* : .:** : .. * *:*. ::*. . . * ..* ** . .*:* . :* * :**:*** :*.*** :***::*****:***********.::**::****:**** ****** **:.* *: :*********.****.**:*.: : :. . . : * . : .* : : :*. ::. ", "identical_positions": 392, "similar_positions": 434, "identity": "10.21%" }, { "cls_id": "homologset.agr.HGNC:32429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ79-1", "uniprot_id": "D3ZZ79_RAT", "id": "D3ZZ79-1", "name": "", "aln": "MAMAERPRPGWASYQNPNPNNCQDMGNSILLLLGLIVCINIGINLVTLLWSRIRILLHRMFH-IICEKESSKLSSLGKLAQPLRKQAYPEVHLRCTMDPVKMTVTPPPTRRRHRHRVPPSRRAHRPIAWAPDTDEEKPPQQRPAVCAHHWDRPKTWESFQSMHEIWEPWAQDGLEQPPQTIRFQPTVEGRPLKTEIRSEQGLEAYVYTVNPPPPSPEALSHKNNATGPGGGAEGEQSQGQPISPPFLGPANVPEIPRRRSSGRIVYDAREVRRRLRELTREVEALSHCYPLVSGSSTAEGTGKDWVYRPLKGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5F289-1", "uniprot_id": "SPEM1_MOUSE", "id": "Q5F289-1", "name": "Spermatid maturation protein 1", "aln": "MAMAERPRPGWASYQNPNINNCQDMGNSILLLLGLIVCINIGINLVTLLWSRIRILLHRMFH-IICEKETS--TSLGKLVQPLRKQTYPKVHLRCTMDPVKMTVTPPPTRRRYRHRAPPSRRARCPIAWAPDTDDEKPPHQHPAICSRHWNDSKDWEGFQSMQEVWEPWTQDGLEQPPQTIRFQPAVEARPLKSEIRSDQGLEAYVYTVNPPPPSPEALSHKNNAAGSGGCVEGEQAQGQPVSPSFLGPANVPEIPRRHSSGRIVYDARDVRRRLRELTQEVEALSHCYPLVSGSSAAEGTGKDWVYRPLKGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4L4-1", "uniprot_id": "SPEM1_HUMAN", "id": "Q8N4L4-1", "name": "Spermatid maturation protein 1", "aln": "MAMVERPRPEWASYHNCNSNSCQDLGNSVLLLLGLIICINISINIVTLLWSRFRGVLYQVFHDTICEKEAPKSSLLRKQTQPPKKQSSPAVHLRCTMDPVMMTVSPPPAHR-HRRRGSPTRCAHCPVAWAPDTDDEKP-HQYPAICSYHWDVPEDWEGFQHTQGTWVPWSQDAPESPPQTIRFQPTVEERPLKTGIWSELGLRAYVYPVNPPPPSPEAPSHKN--GGEGAVPEAEAAQYQPVPAPTLGPAVIPEFSRHRSSGRIVYDARDMRRRLRELTREVEALSGCYPLASGSSTAEETSKNWVYRSLTGR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.***** ****:* * *.***:***:*******:****.**:*******:* :*:::** *****:. : * * .** :**: * ********** ***:***::* :*:* .*:* *: *:*******:*** :* **:*: **: .: **.** : * **:**. *.*********:** ****: * *: **.****.********** **** * *. *.* :* **:... **** :**:.*::**********::********:****** ****.****:** *.*:****.*.**", "identical_positions": 200, "similar_positions": 66, "identity": "63.9%" }, { "cls_id": "homologset.agr.HGNC:3243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH64-1", "uniprot_id": "EHD2_MOUSE", "id": "Q8BH64-1", "name": "EH domain-containing protein 2", "aln": "MFSWLKKGGARGQRPEAIRTVTSSLKELYRTKLLPLEEHYRFGSFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGETEGTVPGNALVVDPEKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPTVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDDMLAQDIAKLMPLLRQEELESVEAGVQGGAFEGTRMGPFVERGP-DEAIEDGEEGSEDDAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPTNLPRRLVPPSKRRQKGSAE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8H8-1", "uniprot_id": "EHD2_RAT", "id": "Q4V8H8-1", "name": "EH domain-containing protein 2", "aln": "MFSWLKKGGARGQRSEAIRTVTSSLKELYRTKLLPLEEHYRFGSFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGETEGTVPGNALVVDPEKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLIFKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESVEAGVQGGAFEGTRMGPFVERGP-DEAIEDGEEGSEDDAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPTNLPRRLVPPSKRRQKGSAE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZN4-1", "uniprot_id": "EHD2_HUMAN", "id": "Q9NZN4-1", "name": "EH domain-containing protein 2", "aln": "MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPFVERGP-DEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKGSAE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QGV7-1", "uniprot_id": "E9QGV7_DANRE", "id": "E9QGV7-1", "name": "", "aln": "-MSAKGMRNRGGKCLKAVHTVTEALKILYRQKLLPLEKYYGFSDFHSSSLEDADFDNKPMILVLGQCSTGKTTFIRYLLEQEYPGSRVGPEPTTDSFTAIMHGEMEGIIHGNALTVDPNKPFRKLSPFGTTFLNRFQCVHLPNRVLESISIIDTPGILSVAKRKMDRGYDFPSVIRWFAEHVDRIILLCDAHKLEISDEFSRTILALRGNEDKLRVVLNKADMVDSQELMRVYGALMWSLGKVFCTPEVLRVYIGSFWTAPMRITDNRKLFEREEGDLFADLQNLPRNSALRKLNDLVKRARLVRAHAYIISCLKDEMPVVFCRGKKRRDLIYDLPTIYSRIQQRYQISPGDFPDCAKMQERLMSHDF-KFKGLKPKLLAGLDELLNTDIAKLMPLLRQEEEEAADQLLIQGGPLGSHRGPFIVGNPFHHSGSNGEIDQASNDEWVVSKDKAKYDEIFYNLSPHEGKLTGTKVKEWMLRTHLPSSVLGRIWKLADVDCDGKLDDEEFALAGHLIEVKLEGFGLPHELPTHLLPPSKRHRKNSEITDDD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . *: :*::***.:** *** ******::* *. ***.:*******.***:** ** *****:**:****** ************.*.*:***: ** : ****.***:******.***.****** *.:***:*************** **:::.******:*:*****:** **** ************.:* ****:***:**********::*:**********:****. *************: *: :.***:*** ** *** *:*.***::****************.****** **.*** ** : :*:::** .**.*:::** .::********* **** **:*** **:.****** .**::* ************* *:.: : *. *:: ***: .* ..: .:** .. .: ****:***:*********:* :***:*:*.* **: *:**.*********:*** ** *********.****.****.*** :** :*:*****::*.* ", "identical_positions": 364, "similar_positions": 113, "identity": "66.42%" }, { "cls_id": "homologset.agr.HGNC:32431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7L8-1", "uniprot_id": "TMIG1_MOUSE", "id": "Q9D7L8-1", "name": "Transmembrane and immunoglobulin domain-containing protein 1", "aln": "MVWKITGPLQAC-QLLLVVLSLPQGRTSSVLTVNGRTENYILDTQHGVQASLECAVQNHTEDEELLWYREDGIVDLKNGNKINISSVCVSPINESDNGVRFTCKLQRDQTVSVTVVLNVTFPPLLSGNGFQTVEENSDVSLVCNVKSNPQAQMMWYKNNSALVLEKGRHQIHQTRESFQLSITKVKKSDNGTYSCIASSSLKMETMDFHLLVKDKVFVMPAEPIIAACVVVVLTMAFALFSRRKRIMKLCGKKNDPNSETAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD96-1", "uniprot_id": "D3ZD96_RAT", "id": "D3ZD96-1", "name": "Transmembrane and immunoglobulin domain-containing protein 1", "aln": "MVRKIIRSLTAS-QLLLLVLSLPQGRTSSVLTVNGRTEDYILDTYYGIQASLECAVQNHTRDEELLWYREAGRVDLKNGNKINTSSVCVSPINESDNGVSFTCKLQRDQTVSITVVLNVTFPPLLSGNGFQTVEEGSDVRLVCNVKSNPQAQMLWYRNNSALVLEKGRHQIQQTRESFQLSITRVKKSDNGTYNCIASSSLKTETMDFHLVVKDKVPVMPIEPIIAACVVVFLTLAFALLSRRERIMKLCVKESGRNSETAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXZ0-1", "uniprot_id": "TMIG1_HUMAN", "id": "Q6UXZ0-1", "name": "Transmembrane and immunoglobulin domain-containing protein 1", "aln": "MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACVVIFLTLCFGLIARRKKIMKLCMKDKDPHSETAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * : ***::* **: *********:**:***** * **** *******.:******** * ****.***** ******.*.*.***: ***:* ***:**::**************.******.*:* ******:******:**:*.* * ***.****:** ********:*:*.*****.***.**** *::****:****. :* *********:.**:.*.*::**::***** *... :*****", "identical_positions": 180, "similar_positions": 50, "identity": "68.7%" }, { "cls_id": "homologset.agr.HGNC:32434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0Y7-1", "uniprot_id": "D4A0Y7_RAT", "id": "D4A0Y7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQTRGSR---GLPEKPLPATTHPPLSSLGAVFILLKSALGAGLLNFPWAFYKAGGLVPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCGPAMGKLCEACFLTNLLMISVAFLRVIGDQLEKLCDSLL--------PDAPQPWYAAQSFTLPLISVLVIFPLSALRDIALQEYTSILGTLAACYLALVITVQYYLWPQGLIRQPG--PLLSP--SPWTSVFSVFPTICFGFQCHEAAVSIYCSMQNQSLPHWTLVSVLSLMACCLVYTLTGVYGFLTFGTEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATQ-------GSPVLADPSGPWVR----------------------------LPLTFLWVAVTLAMALFLPDLSEIIGVIGGLS-AFFIFIFPGLCLISAVDTEPIGPRVKSRTTGSHGYHHEQFEEAGTDINRIGVVLPRRYCCVVWCEAQDCG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HZH7-1", "uniprot_id": "S38A8_MOUSE", "id": "Q5HZH7-1", "name": "Solute carrier family 38 member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQPRGSR---GPLEKPLPAATHPTLSSLGAVFILLKSALGAGLLNFPWAFYKAGGMLPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCGPAMGKLCEICFLTNLLMISVAFLRVIGDQLEKLCDSLL--------PDAPQPWYAAQNFTLPLISMLVIFPLSALREIALQKYTSILGTLAACYLALVITVQYYLWPQGLIRQPG--PLLSP--SPWTSVFSVFPTICFGFQCHEAAVSIYCSMWNQSLSHWTLVSVLSLLACCLVYTLTGVYGFLTFGPEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATR-------GPPVLADPSGPWVR----------------------------LPLTFLWVVVTLTMALFLPDLSEIISIIGGVS-SFFIFIFPGLCLICAVDTEPMGPRVKC-----------CLEAWGILSVLVGTFIFGQSTAVAMVELL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNN8-1", "uniprot_id": "S38A8_HUMAN", "id": "A6NNN8-1", "name": "Solute carrier family 38 member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQTPGSR---GLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGT-----PPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESH--PSLSP--ASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGW-------GPSALADPSGLWVR----------------------------MPLTILWVTVTLAMALFMPDLSEIVSIIGGIS-SFFIFIFPGLCLICAMGVEPIGPRVKC-----------CLEVWGVVSVLVGTFIFGQSTAAAVWEMF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G4J0-1", "uniprot_id": "A0AC58G4J0_DANRE", "id": "A0AC58G4J0-1", "name": "", "aln": "MSVSSLRSVSFGPYTEQMILVFPASMYAEPFAWLTSPQRANTGRTSPFPRTPCLLLGALGALSGDRKSNGDCDSSGPRIRFVSTGIFNKPTCLREHSLLCSGETTQSSSRNQMLRDAAIKCCLRAAALCRIGITWQIDGLHILPEESYLTVAFQLKTGLEALRMEELARESIRSISLLSKPARGSDVPRLGSFGAIFIMLKSALGAGLLNFPWAFEKAGGVNTAISVEMVSLVFLISGLVILGYASSISRQNTYHDVVRNVCGRRIGHLCEICFVFNLFMISVAFLVVVQDQLEKLCLSLYETVTGNTEAEMPHHWYTDYRFALSFMCLIIILPLSIPKEIGIQKYTSVMGTLAATYLSVAVIAKYYLKDTHTADLT---PEHSQGLGSWASMFSVVPTICFGFQCHEASIAIYSSMENKKITHWVFISVTSMIFCLLIYTLTGVFGFLTFGRKVASDILMSYPGNDVVMIIARLLFGISIVTIYPIILLLGRSVILTQILRFWERR----------TIMTPVFEGRCR----------------------------LILTILWITVTLLIAIFVPDMSEVISVIGGIS-AFFIFIFPGLCLIFVMQTEPINHRIRI-----------LLTGWGVVTIVIGAFIFGQSTTIAVMELAHKF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A5WVQ9-1", "uniprot_id": "A5WVQ9_DANRE", "id": "A5WVQ9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEELAKESI---SFLSKSSLETNEPRLGSLGAVFIMLKSALGAGLLIFPWAFAKAGGIHFAVTVEMISLVFLISGLVILGYSSSVSGRNTYQGVVTDICGPAIGKLCEICYVFNLFFISVAFLVIVADQLHKLCLSMYELITGLPESEMPYHWYTDQRFALFLLCLLFIFPLSVPKEISIQKYTSVLGTFAAAYLTVAIVVKYHMRPIHEINLS---PLYSSGISSWDSVFSVIPTICFGFQCHEACVAVYSSMENRRLSHWVFISVLSMLICLLIYSLTGVFGYLTFGKNVAPDILMSYSGGDVTMIVARLLFGISIITIYPIIVLLGRSVIQDPLLRRRLKH----------TAVTESYESRTR----------------------------VALTTAWVTVTLLIAVFIPDISKVISVVGGVS-AFFIFIFPGLCLIFVVQSESVSPTMRY-----------LLVTWGMITLLCGTLIFGQSTSVAIMQLITEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40074-1", "uniprot_id": "AVT6_YEAST", "id": "P40074-1", "name": "Vacuolar amino acid transporter 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVASIRSGVLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFIQARVAKYVPQGRASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWT-----------RNAWLLNRNVQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISYLLPPQSHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIPLIAISLALILYIAIGCAGYLTFGDNIIGNIIMLYP-QAVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFAEENVSISATSADEPTVATESSPLIRDSSLDLNEVIEEESIYQPKETPLRGKSFIVITCSILVASYLVAISVSSLARVLAIVGATGSTSISFILPGLFGYKLIGTEHKTAVPLT---------TKIFKYTGLLLFIWGLIIMITCLTAALKLN----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:: ::::* ***:* :*:** * : .. : : . : * :: : :. : ..: : . :* : : . : : :.*::: :: * : :: * . : :: ::.: *** :.: .*:*::. :. ** : : :* . . .::...* : *.: **. .:: . . : * :.: :: . ::* * *:**** :: :::* *. :.*: : : :: :*: .*: : : . :: * : :* :..: :*: :..::.::.::*. . : : **:*** : * : * * .: . ", "identical_positions": 51, "similar_positions": 145, "identity": "7.73%" }, { "cls_id": "homologset.agr.HGNC:3244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R491-1", "uniprot_id": "EHD3_RAT", "id": "Q8R491-1", "name": "EH domain-containing protein 3", "aln": "MFSWLGNDDRRKKDPEVFQTVSEGLKKLYKTKLLPLEEYYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDVEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEETQRPVQMVKGGAFEGTLQGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPPSKRKVAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXY6-1", "uniprot_id": "EHD3_MOUSE", "id": "Q9QXY6-1", "name": "EH domain-containing protein 3", "aln": "MFSWLGNDDRRKKDPEVFQTVSDGLKKLYKTKLLPLEEYYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDVEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEETQRPVQMVKGGAFEGTLQGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPPSKRKVSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZN3-1", "uniprot_id": "EHD3_HUMAN", "id": "Q9NZN3-1", "name": "EH domain-containing protein 3", "aln": "MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TYP7-1", "uniprot_id": "Q5TYP7_DANRE", "id": "Q5TYP7-1", "name": "", "aln": "MFSWLGTDDRRKKDPEVFQTVSEGLKKLYKTKLLPLEEHYKFHEFHSPALEDADFDNKPMVLLVGQYSTGKTSFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGTMEGLIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELINSLGEIYSRIEREHQISPGDFPNLKKMQEQLQAHDLNKFQPLKMKLLDTVDDMLAHDIAQLMVLVRQEETQRPNQVVKGGAFEGTMNGPFGHGYGEGAGEGIDEVEWVVARDKPMYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSDLPGHLVPPSKRKVPE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.****:**********:*******:*******:*:*******************************:****************************:* :**:***********************************.*********************************************************************:*****************************************************************:*********************************************.*****:*.*.***.*****************:**:****:*:.****** ***:.********************:*** *:*********::****************:.*********************:**:******:***:*****:*******************:*******************.:**.**:*******.*", "identical_positions": 490, "similar_positions": 42, "identity": "91.59%" }, { "cls_id": "homologset.agr.HGNC:32443", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPP7-1", "uniprot_id": "D3ZPP7_RAT", "id": "D3ZPP7-1", "name": "", "aln": "-----------------------MLAPG-------GGPEQRSKLVLQWRQLSWITCWIALCAVEVLPACPFSCTCDSRSLEVDCSGLGLTTVP---PDVPAATQSLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDQLPRSVFQDLVNLTELQLRNNSIRTLDRDLLQHSPRLRHLDLSINGLAQLPQGLFDGLLALRSLSLRSNRLQSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRAVPMEMFNYCSQLEDEN-SAGLDAPG--PPCTKASPEPPKPKPGAEPEPEPSTACPQKQRYRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKR-----QPLMGDPEGEHE-DQKQISSVA--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGX3-1", "uniprot_id": "LRTM2_MOUSE", "id": "Q8BGX3-1", "name": "Leucine-rich repeat and transmembrane domain-containing protein 2", "aln": "-----------------------MLAPG-------GGPEQRSKLVLQWRQVSWITCWIALCAVEVIPACPFSCTCDSRSLEVDCSGLGLTTVP---PDVPAATQSLLLLNNKLSALPSWAFANLSNLQRLDLSNNFLDQLPRSIFEDLVNLTELQLRNNSIRTLDRDLLQHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRAVPMEMFNYCSQLEDENNSAGLDAPG--PPCTKASPEPPKPKPGAEPEPEPSTACPQKQRYRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKR-----QPLMGDPEGEHE-DQKQISSVA--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N967-1", "uniprot_id": "LRTM2_HUMAN", "id": "Q8N967-1", "name": "Leucine-rich repeat and transmembrane domain-containing protein 2", "aln": "-----------------------MLAPG-------SSPGQRGRLALQWRQVSWITCWIALYAVEALPTCPFSCKCDSRSLEVDCSGLGLTTVP---PDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYCSQLEDENSSAGLDIPG--PPCTKASPEPAKPKPGAEPEPEPSTACPQKQRHRPASVRRAMGTVIIAGVVCGVVCIMMVVAAAYGCIYASLMAKYHRELKKR-----QPLMGDPEGEHE-DQKQISSVA--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q6C3-1", "uniprot_id": "A0A8M9Q6C3_DANRE", "id": "A0A8M9Q6C3-1", "name": "", "aln": "----------------------MQLCTA-------PTVGRRRRGNPDSQGFLGVLS-VCATLLQLCAGCPSECVCN--SLEANCSGRSLVSVPA-LTSLPEGTHTLLLANNRLSSLPLSAFANLSTLETLDLSNNYLDNLPSRLFRELSNLSELSLRNNSLTVLDRELFRGLTHLRKLDLSLNGLAAVPLGLLDELQQLTWLSLAGNRLHALERATFEPLVNLQHLELGMNPWECDCNLRDFKHWMEWLIYRGGYVDAVECTLPKDLRGRDIRGVPVEMFNYCLQLEDENGGGTGSTKGGSPPCFRGTAAPSSDSAVVRTEAELPDCV--KQRYRPVSVRRAIGTVVIAGVVCGIVCIMMVAAAAYGCIYASLMAKYQRELKKR-----QPLMGDAEAETDPEEKQISSVA--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B753-1", "uniprot_id": "A0ACD6B753_DANRE", "id": "A0ACD6B753-1", "name": "", "aln": "MNILISSGLMTLVSLCGTSKSCPLLCSCNINQTDCSHLYQLASLDSILEQLPFDTTNLNLSKNNFTTVEPGSFSNLSALLQLDYSRNLLSAINPGCFSNLSGLLHLDLSRNLLSRVFPSSFSHLNSLEFLDLSVNLLVRLPVNLFSDLSSLNELVLRDNRLKELNPAQFKGLTELRRLDLSLNSLSHVPTHLLDGLQNLLWLSLVGNKLKTLDRSSLESANTLQQLLLEGNPWNCNCKLIPLKYWLEWIVYTGGRVDSPNCSFPTDLQGKDLASLPMELFRHCYPLQLQT------------------RKPSAPEAHQGPSGD-----CMRQRYRAVSVRRATATVVVAGVVCSVVCVLMVVTATYGCIYATLVAHQQQQMLQRKRQQQEPLMVEKEPAHDEKEDLMPTIGKGAEAMECVGWMAFPPEVCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. : . . : : . * . *: : * * :: . . * * .* ** : :*::*..*: **** * * .** :* :* .*.** **:* : *: :: . **:****:*.*: :* *:* * * *** .*:*: *:* ::*. .** * : ***:*:*:* :*:*:**: * ** :* *::*.:*:*:*: :*:*:*.:* *: :. *. .. .. : :**:*..***** .**::*****.:**::**.:*:******:*:*: :::: :* :*** : * : .:. :.::. ", "identical_positions": 112, "similar_positions": 111, "identity": "25.99%" }, { "cls_id": "homologset.agr.HGNC:32448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3I5G5-1", "uniprot_id": "FOXI2_MOUSE", "id": "Q3I5G5-1", "name": "Forkhead box protein I2", "aln": "-----------------------------------------------------------------------------MAGFCDSLGSCSVP-----------HGLTRAIAHPPSYGRTDL---SSGRRLW-VNSAALSPAPYATGPGPAPSYAAA------------------------------------TLAVPG---SLLG---------------ASGGLAGADLAWLSLSGQQEL----------------------------------------------------------LRLVRPPYSYSALIAMAIQSAPLRRLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTLDPNCEKMFDNGNFRRKRRRRGETSEAAVPGASSP---EGTALEPRGSTPQDPQTSPSPSE-ATTTCLSGFSTAMGALAGGFGALPDGLAHDFSLRRPPPTAAAHSPQIPNTAPGFAPGHQTGATGFRMGHLIYSRDGTEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63248-1", "uniprot_id": "FOXI2_RAT", "id": "Q63248-1", "name": "Forkhead box protein I2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVRPPYSYSALIAMAIQSAPRRRLTLSQIYQYVAGNFPFYKRTKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWMLDPNCEKMFDNGNFRRKRRRRGE----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQN5-1", "uniprot_id": "FOXI2_HUMAN", "id": "Q6ZQN5-1", "name": "Forkhead box protein I2", "aln": "-----------------------------------------------------------------------------MATYCDDLGPSSAP-----------PGQAQATAHPPGYEPGDLGAVGGGPLLW-VNAPALSPKSYASGPGPAPPYAAP------------------------------------SYGAPG---PLLG---------------APGGLAGADLAWLSLSGQQEL----------------------------------------------------------LRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPALEPPSAACLDLQASPSPSAPEAATCFSGFASAMSALAGGLGTFPGGLAGDFSFGRRPPTVATHAPQTLNPSPGFAPGHQTAAAGFRLSHLLYSREGTEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLN-KWNAGKLSKIRRGASVTR-----------QLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** **:::*: ** *:* ::*::**::::.*:.**: :: .****:*******..*:***: .: *** * :. : .: * * ::. : : . ", "identical_positions": 36, "similar_positions": 40, "identity": "6.94%" }, { "cls_id": "homologset.agr.HGNC:3245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3Z7-1", "uniprot_id": "Q8R3Z7_RAT", "id": "Q8R3Z7-1", "name": "", "aln": "MRKDLRSLLNNERAPVTQRLMIGRCGRGRARERAVARASPAPRVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSMFGKENKKRELIFRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMSLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQP2-1", "uniprot_id": "EHD4_MOUSE", "id": "Q9EQP2-1", "name": "EH domain-containing protein 4", "aln": "----MFSWMGRQAGGRERSGGMDAVQTVTGGLRSLYQR----KVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H223-1", "uniprot_id": "EHD4_HUMAN", "id": "Q9H223-1", "name": "EH domain-containing protein 4", "aln": "----MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLR----KVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKAD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8X4-1", "uniprot_id": "A0AB13A8X4_DANRE", "id": "A0AB13A8X4-1", "name": "", "aln": "----MFTWVNKEQGGRNKEG--DMFQTVTEGLQSLYTK----KLLPLEETYLFHDFHSPALEEADFQSKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDGFIAVMYNDNEGVVPGNALVVDPKKPFRKLNSFGNSFLNRFICSQMPNQVLQSISIIDTPGILSGEKQRISRGYDFSEVLRWFGERVDRIILLFDAHKLDISDEFSEAIRAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVVRVYLGSFWAKPLQNAENRRLFEAETQDLFRDIQGLPRNAALRKLNDLIKRARLAKVHAYIISYLKKEMPSLFGKEKKKEELIAHLPEIYQILQREHHISPGDFPNVIKMQEQLQHYDFSKFPSMKVKLIESVDRMLSTKISYLMNMIREEESKQPPQMVKGGAFEDSSDGPFGHGYGEGVSAGADTEDWIVSRDKHRYDEIFYTLMPVNGRVTGINAKKEMMNSRLPNTVLGKIWKLADCDKDGMLDDEEFALAQHLIKIKLEGFELPIELPNHLVPPSHRKN-PTADILYNHQED", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :..: . : . ::: ::*****:* **:*******:***:.***:**********************************.******.:.** .****************. ***:*****:***:*****:***:**:*****************.:**:**.*************************:********************************************:***:*****:****::********:********.**::**:****************************.:****:**.*** :***** ****::**.****:* *****::***:** *:* ****:**.**:.*** **.:* :** . *.*:*:****:.:::***.:*****.. *** *:*:*::** ***:**** *:**:::*:******:.*:***:************ *****:******:*******:*:*** .** *********. *.** ", "identical_positions": 395, "similar_positions": 101, "identity": "70.92%" }, { "cls_id": "homologset.agr.HGNC:32456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCQ2-1", "uniprot_id": "D3ZCQ2_RAT", "id": "D3ZCQ2-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAADTGSWCVYAVLRFFYSLFFPGLIICGVLCVYLVIGLWVIRRHLQRKK---KSASTSKNGKDQMVVAFFHPYCNAGGGGERVLWCALRALQKKYPDAVYVVYTGDIH----VSGQQILEGAFRRFNIKLVHP-VQFVFLRKRYLVEDSRYPHFTLLGQSLGSILLGWEALMQRVPDVYIDSMGYAFTLPLFK-YVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTNIVYPPCDVQTFLDIPLH----EKKVTPGHLLVSIGQFRPEKNHALQIKAFAKLLNEKAAESR--HSLKLVLIGGCRNKDDEFRVNQLRRLSENLG--VQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVIPHEGQ-------------------------ITGFLAESEEG--------------YAETMAHILSLSPEKRLRIRETAR-ASLSRFSDQEFEVAFLCSVGKLLT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TZM9-1", "uniprot_id": "ALG11_MOUSE", "id": "Q3TZM9-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAADTGSWCVYAVLRFFYSLFFPGLMICGVLCVYLVIGLWVIRWHLQRKK---KSVSTSKNGKEQTVVAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDIN----VSGQQILDGAFRRFNIKLAHP-VQFVFLRKRYLVEDSRYPHFTLLGQSLGSILLGWEALMQRVPDVYIDSMGYAFTLPLFK-YVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTNIVYPPCDVQTFLDIPLH----EKKVTPGHLLVSIGQFRPEKNHALQIKAFAKLLNEKAAELG--HSLKLVLIGGCRNKDDEFRVNQLRSLSENLG--VQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTVILAHNSGGPKLDIVIPHEGQ-------------------------ITGFLAESEEG--------------YADSMAHILSLSAEERLQIRKNAR-ASISRFSDQEFEVAFLCSMEKLLT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TAA5-1", "uniprot_id": "ALG11_HUMAN", "id": "Q2TAA5-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAAGERSWCLCKLLRFFYSLFFPGLIVCGTLCVCLVIVLWGIRLLLQRKK---KLVSTSKNGKNQMVIAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDVN----VNGQQILEGAFRRFNIRLIHP-VQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFK-YIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTNIVYPPCDVQTFLDIPLH----EKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESP--PSLKLVLIGGCRNKDDELRVNQLRRLSEDLG--VQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGD-------------------------ITGFLAESEED--------------YAETIAHILSMSAEKRLQIRKSAR-ASVSRFSDQEFEVTFLSSVEKLFK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW24-1", "uniprot_id": "ALG11_DANRE", "id": "Q7ZW24-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "-----MSAHDHFSLCLCDLIRLLWSLMLPCFYLSFLLTTILFLFIMGVRSWLQMKR---KTRRVQ-DGRP--AVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQG----VTAEEILDGARRRFNIRLPRP-VKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFR-YLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEAEPAGREAVKLVLIGGCRNQEDEDRVLMLRGLCQELG--IADRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGG-------------------------PTGFLADDEDN--------------YADAMERILSMSPATRLEMRRRAR-LSVSRFSDQEFEGSFLSAMEPLMSTLRA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP06-1", "uniprot_id": "Q9VP06_DROME", "id": "Q9VP06-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "---------------------MFLFLFLLWLLLSLVLVAVLS-FLFLRQWLLGRKN---KLHTSSENGIN---VGIFHPYCNAGGGGERVLWCAVRALQEKYQNARMVIYTGDID----ASPNSILQKAKNVFNIAVDSDNVKFVFLKQRHWIEAKNYPHFTLLGQSIGSMVVGLEALCRFPPDIYIDTMGYAFTYPLFR-YLAQSKVGCYVHYPVISTDMLKRVQQRQMSHNNKKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWDVPFKTHRVYPPCEVSHLKSLQHT----EKGDE--FIILSVGQFRPEKDHPLQLQAIYELRTLLAQDEALWNQIKLVIVGSCRNEDDYERLKNMQDLTKHLS--LENNVQFSVNVPYEDLLKLYQTAHIGIHTMWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIVETSAGS-------------------------QNGFLATDAVE--------------YAENILNIIVNNSE-MNGIRNAAR-ASVERFSEQEFEKNFLRAVSTLFTNN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53954-1", "uniprot_id": "ALG11_YEAST", "id": "P53954-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "MGSAWTNYNFEEVKSHFGFKKYVVSSLVLVYGLIKVLTWIFRQWVYSSLNPFSKKSSLLNRAVASCGEKNVKVFGFFHPYCNAGGGGEKVLWKAVDITLRKDAKNVIVIYSGDFVNGENVTPENILNNVKAKFDYDLDSDRIFFISLKLRYLVDSSTWKHFTLIGQAIGSMILAFESIIQCPPDIWIDTMGYPFSYPIIARFLRRIPIVTYTHYPIMSKDMLNKLFK----------MPKKGIKVYGKILYWKVFMLIYQSIGSKIDIVITNSTWTNNHIKQIWQS-NTCKIIYPPCSTEKLVDWKQKFG--TAKGERLNQAIVLAQFRPEKRHKLIIESFATFLKNLPDSVS---PIKLIMAGSTRSKQDENYVKSLQDWSENVLKIPKHLISFEKNLPFDKIEILLNKSTFGVNAMWNEHFGIAVVEYMASGLIPIVHASAGPLLDIVTPWDANGNIGKAPPQWELQKKYFAKLEDDGETTGFFFKEPSDPDYNTTKDPLRYPNLSDLFLQITKLDYDCLRVMGARNQQYSLYKFSDLKFDKDWENFVLNPICKLLEEEERG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : * : : : * : . . ..:************:*** *: .: . *:*:** .. :.**: . *: : : *: *: * :: . : ****:**::**:.:. *:: . **::**:**:.*: *:: :: : *.*** :*.***. : : :. : . *: *: :* :* *. : ::.**:** .** :* :****... : . : :.****** * * :.:: : . :**:: *. *.::* : :: :.: . :.*. *:.::.: : :*:::********.:** **:* : :.* *.** **** . . .**: . :: : .* . : : *: :**: :*: : : : ", "identical_positions": 113, "similar_positions": 148, "identity": "20.04%" }, { "cls_id": "homologset.agr.HGNC:32458", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ARR7-1", "uniprot_id": "A2ARR7_MOUSE", "id": "A2ARR7-1", "name": "", "aln": "----------------MDLVTYDDVQVNFT-QEEWALLDPSQKS-----------------LYKDVMLETHRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPSEFIQCGKA---FAYESHSQRYEIKHTGEKHHDCNQCGKAFARS----------------------------DDLQKHKRTHTGEKPYKCNQCGKSFARSGDLQKHKR----------------------------THTGEKPYECNQCG------KAFARNCDLQKHKR---------THTGEKPYECN--------------------QCGKAFARKCDLQKHKRTHTGEKPYECKQCGKAFAESSTLQIHKRTHTGEKPYECNQCGKAFKRSSDLQKHKRTHTGEKPYECKQCGKAFAESSTLQIHKRTHTGEKPYECNQCGKAFKRSCELQKHKRTHTGEKP------------------------------------------------------------------------------------YECNQCGKAFKRSCELQKHKRIHTGEKPYKCNQCGKAFTQSSHLQIHKRTHTGEKPYECNQCGKAFARNCDLQKHKQTHTGEKPYECNQCGKAFARKCDLQNHKQKHTGEKPYEC--KQCGKAFAQSSHLRIHKRTHTGEKPYECNQCGKAFKRRSDLQVHKRTHTGEKP--YKCKQCGKAFARSGGLQKHKRTHTGERPNECN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARX0-1", "uniprot_id": "A2ARX0_MOUSE", "id": "A2ARX0-1", "name": "", "aln": "----------------MDLVTYDDVQVNFT-QEEWALLDPSQKS-----------------LYKDVMLETYRNLKAIGYIWEGHTSEDHFQTSRSHGRHERSCTAVKPSEFIQCGKA---FAYQSLRQRHERTHKGEKDYYCNQCGKAFIISSHLQIHKRRNTGEKPYECNQCCKTCTVRSDLQIHKQTHTGEKPYECNQCGKAFAGSGDFQKHKRRQRGEKPYECNQCGKTFAVRSDLRIHKRTHTGEKPYECKQCS------KAFIRRGDLQIHKR---------THTGEKPYECN--------------------QCGKAFIRSADLQIHKRTHTGEQPYECNQCGKAFIRSGDLQIHKRIHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFIRSGDLQIHKRTHTGEKPYECNQCGKAFIRSGDLQIHKRTHTGEKP------------------------------------------------------------------------------------YECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFIRSGDLQIHKRTHTGEQPYECNQCGKAFIRSGDLQIHKRTHTGEKPYEC--KQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFIRSGDLQIHKRTHTGEKP--YECKQCGKAFTKSSNLQIHERTHTGEKPYECNQCGKAFIHSGNLKRHKRTHTGEKLYEGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N769-1", "uniprot_id": "K7N769_MOUSE", "id": "K7N769-1", "name": "", "aln": "----------------MDAMTFDDVHVNFT-KEEWNLLEPSQMN-----------------LYKDVMLETYWNLTSIGYKWEDHHIEEPCQSSRRHTRHVR---------------------------------------------------------------------------------------SHSWKKLYECNQCGKAFTSHSSLRYHKR----------------------------THTGEKPYECNHCG------KAFARPAHLQRHKR---------THTGEKPYECN--------------------QCSKAFSCHSGLRYHKRTHTGEKPYECNQCGKAFARPADLQCHKRTHTGEKPYECNQCGKAFARPANLQCHKRTHTGEKPYECNQCGKAFSCQGGLRYHKRTHTGEKPYECNQCGKAFARPSHLQCHKRTHTGEKP------------------------------------------------------------------------------------YECNQCGKAFSSHISLRYHKRTHTGEKPYECNQCGKAFSGHSGLRYHKRTHTGEKPYECNQCGKAFATPSHLQCHKRTHTGEKPYECNQCSKAFARPAHLQHHKRTHTGEKPYEC--NQCGKAFARLSHLQCHKRTHTGEKPYECNQCGKAFSCHNSLRYHKGTHTGEKP--YECNQCGKALATSTHLQCHKRTHTGE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P6H7-1", "uniprot_id": "A0A1W2P6H7_MOUSE", "id": "A0A1W2P6H7-1", "name": "", "aln": "----------------MDAVTYEDVHVNFS-HEEWALLDSSQKS-----------------LYRDVMLETYWNLTAIGYKLEDPNVEEYYQSYRRHRRYNICHCGYKPCEHKGYGKNQYIFACNNFLQIYDRIQTEEKPYRCSQCSKAFANFRSLRKHEKNHTREKPYECSQCSKAFVSRSSLQIHERTHTREKLYDCNECGKAFSTRSHLQIHKR----------------------------THTGEKPYDCSECG------KAFARSSTLLIHKR---------SHTGEKPYGCN--------------------ECGKAFACRSHLQIHKRTHTGEKPYDCDECGKAFATRRHLQIHERTHTGEKPYECNQCGKAFIGRSHLQIHKRVHTGEKPYECNQCGKAFAYNSDLHRHEIIHTGEKPYGCNQCGKAFANRSSLRNHEEHHTLEKP------------------------------------------------------------------------------------YECTLCGKAFAYCSNLYIHERCHTGEKPYVCTQCGKAFARRSHLHIHERCHTGEKPYVCTQCGKAFARCSHLHVHERIHAGEKPYECNQCGKAFLLRSSLLIHERTHTGEKPYVC--NQCGKAFARQSHLQIHERSHTGEKPYECNQCSKAFVCRSNLQMHERTHTGERP--YECNQCGKAFSRRSLLQKHERSHSGEKPYACNQCGKAFASRSSLRNHEKHHNIEKPNECNQCAKAFTSFPPSSNI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LT76-1", "uniprot_id": "F1LT76_RAT", "id": "F1LT76-1", "name": "", "aln": "----------------MDAVTYDEVHVNFT-QEEWALLDRSQKS-----------------LYRDVMLETYKNLTAIGYNWEDYNIEEHCQSSRRRERHETSHPGEKPSEYTHCGKV---LAYQSHPQKHERIHTGKKPYDDTQCGEAFACHSN-LVHKRIHTGVKPYECNHCGKAFAYPSNLQRHERIHTGEKPYECNQCGKAFVTHSDLQIHKR----------------------------THTGEKPYECNQCG------KAFAYHSNLQRHER---------IHTGEKPYECN--------------------QCGKAFAWHRNLQRHERIHTGEKPYECNQCGKTFAHDSNLHIHKRKHAGEKPYECNHCGKAFPCHNLLQIHKRTHTGEKPYECNQCGKTFAYHSYLQMHERIHTGEKPYECNHCGKAFSQHSSLRVHKRTHTGEKP------------------------------------------------------------------------------------YECSQCGEAFAYHSHLQIHKTTHTGEKPFQCNQCGKAFVYNNHLLVHKRTHTGEKPYECNHCGKAFSQRSSLCVHKKTHTGEKPYKCNECGKAFARNSHLQRHKRIHTGEKPHEC--NQCGKAFARHSTLQLHKRKHAGEKPYECSQCGKAFPSHNLLHIHKRTHTGEKP--YECNQCGKTFAYHSHLQVHGRIHTGEKPYVCNQCGKAFACHRNLRVHKRKHSGEKPYECNHSGKAFSQHSSLQVHKRKRTGEKSYEL-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AGB5-1", "uniprot_id": "A0A8I6AGB5_RAT", "id": "A0A8I6AGB5-1", "name": "", "aln": "---------MLANNTAQQCHLFPAFLLSFAYLPEWALLNPSQKS-----------------LYKDVMLETYKNLTAIGYNWEDHYIEEEFQSSRRYGRHETGYTGEKPYECTHYGTG---FASHGHLQRHKGTYTGEKPYECKQCGKAFAWN----------------------------CHLQIHKRTHTGEKPYECDQCGTAFASHGHLQRHKR----------------------------THTGEKPYECNQCG------KAFSQHSSLQVHKR---------THTGEKPYECN--------------------QCGKAYARHSHLQRHKRTHTGEKPYECNQCGKAFAYHNSLQYHTRTHTGEKSYECKQCGKVFVCRDHLQIHKRTHAGQKRYECKQCGKVFAFHSHFQRHKR-HIGEKPYECNQCDKAFASHNNLQKHIKRHTGEKS------------------------------------------------------------------------------------YKCNQCDKTYAHYSHLQTHKRIHTGEKPYKCNQCGKAFSQHSSLQVHKRTHTGEKPYECNQCGKSYARHSHLQRHKRTHTGEKPYQCNHCGKAFAYYNSLQYHKRAHTREKSYKC--NQCDKAFASHSNLQKHIR-HTGD--YKCNQCVKTFTHHSHLQRHKRTHTGEKP--YECNQFGKIVAQHSTFHSIKKAHMGWRDGSVVKS-TECSSRGPEFNSQLPHGGSQPSVMESEALFWCA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AHP9-1", "uniprot_id": "A0A8I6AHP9_RAT", "id": "A0A8I6AHP9-1", "name": "", "aln": "-MISLGMPRSGQRPGTKGIVTYDDVHVHFT-QEEWALLDPSQKS-----------------LYKDVMLETYRNLTAIGYVWEDHNIEERFQSSRRYGRHTR---------------------------------------------------------------------------------------SLTKEQLSEFIQCGKTSTFQSHNQRQER----------------------------IHTGEKPYEGVQHC------EAFAYRSSLHIHKT---------KLGREKPYECN--------------------QCGKDFASHSCLQRHKRVHKGEKSHECSQSGKALGCQSGLQYHKRTHTGEKPYKCNQCGEAFVYHSDLQKHKRTHTGQKSFKCSQCGKAFSGNRHLLRHKRIHTGEKPYECNQCGKDFSQHSSLQRHKRIHTGEKP------------------------------------------------------------------------------------YECKQCGKGFACQSGLYIHKRTHTGEKPYECNQCDKAFACQSGLLYHKRTHTGERPYECNECGKAFIHHSHFQTHKRTHTGEKPFECDQCGKAFARNNHLLTHRRIHTREKLYER--KKGGKPLASHS----------------------------SLQVHKRTLTGEKP--Y-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NP11-1", "uniprot_id": "ZN716_HUMAN", "id": "A6NP11-1", "name": "Zinc finger protein 716", "aln": "----MAKRPGPPGSREMGLLTFRDIAIEFS-LAEWQCLDHAQQN-----------------LYRDVMLENYRNLVSLGIAVSKPDLITCLEQNKEPQNIKR--------------------------------------------------------------------------------NEMVAKHPVTCSHFTQDLQSEQGIKDSLQKVILRR---------------------------YGKCGQEDLQVKKCC------KSVG---ECEVHKGGYNYVNQCLSATQNKTFQTH--------------------KCVKVFGKFSNSNRHKTRHTGKKHFKCKNDGKSFCMLSRLNQHQIIHTREKSYKCEECGKSFNCSSTLTRHKRIHTGEKPYRCEECGKAFSWSASLTKHKRIHTGEKPYTCEERGKVFSR-STLTNYKRIHTGEKP------------------------------------------------------------------------------------YTCEECGKAFSRSSTLTNHKRIHTGERPYKCEECGKAFSLSSTLKKHKIVHTGEKLYTCEECGKAFTFSSTLNTHKRIHTGEKPYTCEECGKAFSLPSTFTYHKRTHTGEKPYKC--EECGKAFNCSSTLKKHKIIHTGEKLYKCKECGKAFTFSSTLNTHKRIHTGEKP--YKCEECDQTFKWHSSLANHKNMHTGEKPYKYE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PGG2-1", "uniprot_id": "M9PGG2_DROME", "id": "M9PGG2-1", "name": "", "aln": "MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNPGAIGATPAQWGSEMYPNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQPQSPPGGGQEARDN---GSGDGRQQQVSPSSSPYPSVQQQQRANGAGDEDPMNHQLANQQNPAPNQNQSSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQGGMLAPPG-----------FPPLHYLNKGVLPMEQSGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGAGANGSGGVGGATGASVGVGSVGVTSGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNTTKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQVANHLMNDAKSLAAQQFLNNNNPSAVDNKANILPVRSIASNAAAAAVVQQSVVKNELYFPQCYGPPFQHPFQAQQQQAQQPSVAHANGGPTPPVTVTVANSVASGVVVQQNASASVVAQXHPTTAATGAQQQQPSAPQQQHHPPPPPPTSTAHHIASAAAAVTAVTPSSAHASPVAAPQTVTLSITLPPPPASHTVHPGHPGHPGHPGVANGAAPPPPTLSHAIPIHPHIHSIFGSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :* :* :: : :* : . .: : . : * : :: :: : : . :: *.. : ..* ** : * * *: :.: *..**: * * * * *:.:* : * *.: * : * * ****: * . .* * * : . * .. * *.: : * * * .:*: * :*.* * . * * **.*: : * * : : : * : *:**:*: * .*.* * : * : * :: . : : : . . :: :: ", "identical_positions": 62, "similar_positions": 88, "identity": "6.51%" }, { "cls_id": "homologset.agr.HGNC:32459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZA3-1", "uniprot_id": "ZCH12_RAT", "id": "Q5HZA3-1", "name": "Zinc finger CCHC domain-containing protein 12", "aln": "MASILSRMGNSRGQNSPLPPWAHSMLRSLGRSLGPLMASMAERNMKLFSGRAEPAQGEETFENWLSQVTAVLPDWHMPEEEKVRRLMRTLRGPAREVMRLLQAANPCLDVEDFLRAMKLVFGESESSVTAHSKFVNTVQEPGEKPSLYVIRLEVQLQNAIQAGVFAEREANQARLHQLLVGAEMSTDLRFRLKSLLRVYAN-EPERLPNFLELIRMIREEEEWEEAFIHPKRPRRSQS-VERALSP-TFQSSPPVMISSIDCN--VIEIDDSPDDSDEDVILVEPDDPPLPSSSAGPSFLGRAVSEDQVLVIESPNIFEIQAPSTSSGAGRKNNNNFGELRRARKRKHTVHCSHCGEEGHSKETCDNESDRGQVFENLIITLQELTHTEERAREIFGEAIGLSELH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZA5-1", "uniprot_id": "ZCH12_MOUSE", "id": "Q9CZA5-1", "name": "Zinc finger CCHC domain-containing protein 12", "aln": "MASILSRLGSSRGQNSPLPPWAHSMLRSLGRSLGPLMASMAERNMRLFSGRAEPAQGEETFENWLSQVTGVLPDWHMPEEEKVRRLMRTLRGPAREVMRLLQAANPGLDVEDFLRAMKLVFGESESSVTAHSKFVNTVQEHGEKPSLYVIRLEVQLQNAIQAGVFAEREANQARLHQLLVGAEMSTDLRFRLKNLLRVYAN-EPERLPNFLELIRMIREEEEWEETFINPKRPRRAESVMERALSPMAFQSSPPIMISSIDCN--VIEIDDSPDDSDEDVILVEPEDPPLPSSSAS-SFLGRAVSEDQVLVIESPNIFEIQAPSTSSGAGRKNNRGFGELRRARKRKHTIHCSHCGEEGHSKETCDNESDKGQVFENLIITLQELTHAEERARGAPGEPIGLSEPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CG32-1", "uniprot_id": "ZCC18_HUMAN", "id": "P0CG32-1", "name": "Zinc finger CCHC domain-containing protein 18", "aln": "MASITACVGNSRQQNAPLPPWAHSMLRSLGRSLCPLVVKMAERNMKLFSGRVVPAQGKETFENWLIQVNEVLPDWSMSEEEKLKRLMKTLRGPAREVMRLLQAANPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGEKASLYVIRLEVQLQNAIQAGILAEKDANQTRLQQLLLGAELNRDLRFRLKHLLRMYAN-KQERLPNFLELIKMIREEEDWDDAFIKRKRPKRSEPIMERAASPVAFQGAQPIAISSADCNCNVIEIDDTLDDSDEDVILVVSLYPSLTPTGAP-PFRGRARPLDQVLVIDSPNNSGAQSLSTSGGSGYKND-GPGNIRRARKRKYTTRCSYCGEEGHSKETCDNESNKAQVFENLIITLQELTHTEERSKEVPGEHSDASEPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VD24-1", "uniprot_id": "ZCC18_MOUSE", "id": "Q8VD24-1", "name": "Zinc finger CCHC domain-containing protein 18", "aln": "MASLLARMGNSRRQNAAFMPFAHSMLRALGRSLGPLIANIAERNIQSFSGRAELGPGEETFENWLSQVHEVLPDWPMSEEEKIKRLMRTLRGPAREAMRLFQADNPNLNVAEFLRAMKLLFGASESSITAHGKFLSTLQAQGEKPSLYVIRLEVQLQNAIQAGVLPQSEANRTRLHQLLVGAELSRELRTKLKGLLQMHAHNEQENLPDFLELIRMIREEEDWDETFLRNKRPRRSETVMERAASPVVFQGSLPIVIGSADCN--VIEIDDSQDDSDEDVILVEPEDPPLSSPGAS-SLRGTASTQEEMLIIESPDDFDEESPSTSSGSGQRNN-GPGDLGRTRKRKYPIRCPHCGEEGHAKETCDNTSNKGQVFENLIVTLQELTHMERPKPSVPY---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJH1-1", "uniprot_id": "A0A8I6AJH1_RAT", "id": "A0A8I6AJH1-1", "name": "", "aln": "MASLLARMGNSRRQNAAFMPLAHSMLRALGRSLGPLIANIAERNIQSFSGRAELAPGEETFENWLSQVHEVLPDWPMSEEDKIKRLMRTLRGPAREAMRLFQADNPNLNVAEFLRAMKLLFGESESSITAHGKFLNTLQAQGEKPSLYVIRLEVQLQNAIQAGVLPQSEANRTRLHQLLVGAELSRELRIKLKGLLQMHAHNEQESLPDFLELIRMIREEEDWDETFLRNKRPRRSETVMERAASPVVFQGSLPIVIGSADCN--VIEIDDSQDDSDEDVILVEPEDPPLSSPGTS-SLRGTVSTQEEMLVIESPDESDEESPSTSSGSGQRNN-GPGDVGRTRKRKYPIRCPHCGEEGHAKETCDNTSNKGQVFENLIVTLQELTHMERPKPPAPY---------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: : :*.** **:.: * ******:***** **:..:****:: ****. . *:******* ** ***** *.**:*::***:********.***:** ** *.* :*******:** ****:***.**..*:* ***.******************::.: :**::**:***:***:. :** :** **:::*: : * **:*****:******:*:::*:. ***:*::. :*** ** .**.: *: *.* *** ******: ********** . *.*....: .: * . . :::*:*:**: :: ***.*:* :*: . *:: *:****:. :*.:******:****** *::.*******:******* *. ", "identical_positions": 224, "similar_positions": 108, "identity": "55.17%" }, { "cls_id": "homologset.agr.HGNC:3246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYD8-1", "uniprot_id": "B2RYD8_RAT", "id": "B2RYD8-1", "name": "ETS homologous factor", "aln": "-------------MILEGSGVMNLNPANNLLHQPPA-WTDSYSACNVS---SGFFGGQW-HEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDISGEHLCSMSLQEFTRAAGSAGQLLYSNLQHLKWNGQCSSDLFQSAHNVIVKTEQTDPSIMNTWKEENYLYDPSYGSTVDLLDSKTFCRAQISMTTSSHLPVAESPDMKKEQDHPVKSHTKKHNPRGTHLWEFIRDILLSPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70273-1", "uniprot_id": "EHF_MOUSE", "id": "O70273-1", "name": "ETS homologous factor", "aln": "-------------MILEGSGVMNLNPANNLLHQQPA-WTDSYPTCNVS---SGFFGSQW-HEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDISGEHLCSMSLQEFTRAAGSAGQLLYSNLQHLKWNGQCSSDLFQSAHNVIVKTEQTDPSIMNTWKEENYLYDPSYGSTVDLLDSKTFCRAQISMTTSSHLPVAESPDMKKEQDHPVKSHTKKHNPRGTHLWEFIRDILLSPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZC4-1", "uniprot_id": "EHF_HUMAN", "id": "Q9NZC4-1", "name": "ETS homologous factor", "aln": "-------------MILEGGGVMNLNPGNNLLHQPPA-WTDSYSTCNVS---SGFFGGQW-HEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TDV0-1", "uniprot_id": "A0AB32TDV0_DANRE", "id": "A0AB32TDV0-1", "name": "ETS homologous factor", "aln": "MSVISSTYVQHWIMVLQASGVMSIPATVSVDNQLPASWTTHYNCTDVSMMTSNFTSRLWTQDPHPQNWTKFQVWEWLQQTLDMHQIDATSIPFQNFDLDGRQLCNMSFQDFTRAAGSVGSILFQSLTDLKWNGQYGQTDMFTPADIKTEIDADFPCSILPFKEE-----SSFYSNPELFDIKSSFQPSSILPS----PAPSSPDPKRSQ-------VKRHNPRGTHLWEFIRDILLNPERNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGRNARGWRESEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:..***.: . .: :* ** ** * :** *.* . * :: *** ***:*******: ** :*:**..****:**:.*.:**.**:*:******:.*.:*:..* .****** .. : :. :: .: : *. : .:*:* ..: *. :*:* *: :.. :.: *...*** *:.* .*:*****************.*::*************:*****************************************************:*******.*:", "identical_positions": 167, "similar_positions": 79, "identity": "52.52%" }, { "cls_id": "homologset.agr.HGNC:32460", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8MTY0-1", "uniprot_id": "ZN724_HUMAN", "id": "A8MTY0-1", "name": "Zinc finger protein 724", "aln": "------MGPLTFMDVAIEFSVEEWQCLDTAQQN---LYRN------------VMLENYRNLVFLGIAVSKPDLITCLEQGKE------------------------------------PWNMERHEMVAKPPGMCCYFAQDLRPEQSIKASLQRIILRKYEKCGHHNLQLKKGYKSVDEYKVHKGSYNGFNQCLTTTQSKIFQCDKYVKDFHKFSNS---------NRHKTEKNPFKCKECG--------KSFCVLSHLTQHKR--IHTTVNSYKLEECGKAFNVSSTLSQHKRIHTGQKHYKCEECGIAFNKSSHLNTHKIIHTGEKSYKREECGKAFNISSHLTTHKIIHTGENAYKCKECGKAFNQSSTLTRHKIIHAGEKPYICEHCGRAFNQSSNLTKHKRIHTGDKPYKCEECGKAFNVSSTLTQHKRIHTGEKPYKCEECG--------------KAFNVSSTLTQHKRIHTGEKPYKCEECGKAFNTSSHLTTHKR--------IHTGEKPY------KCEECGKAFNQFSQLTTHKIIHTGEKPYKCKECGKAFKRSSNLTEHRIIHTGEKPYKCEECGKAFNLSSHLTTHKKIHTGEKPYKCKECGKAFNQSSTLARHKIIHAGEKPYKC--EECGKAFYQYSNLTQHKIIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTGEKPYKCKECGKAFNQCSNLTTHKKIHAVEKSDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "L7N1X4-1", "uniprot_id": "L7N1X4_MOUSE", "id": "L7N1X4-1", "name": "", "aln": "-----MEDMLSFWDVAIYFSAEEWDCQGPAQWD---LYRD------------VTLENYSNLVFLGLASSKPYLVTFLEQIQE------------------------------------PSDVKRQAAITVHPGGKCYTCKECGKGFEHKKVYQNHWRIHLRVKSYKCEECGKSFHFPSLLSAHKRKHTGEKLYSSEDSGKDFHCP------SLLSQN---------KIVHTEEKPYKCEDCG--------KGFHYPSRLSDHKK--IHTGEKPHKCEICGKAFDYPSRLSNHKRIHTGEKPYKCELCDKTFHDPSKLSQHKIIHTGEKPYKCEVCGKTFHYPSILSKHKIIHTGEKPYKCEVCGKTFHYPSILSKHKIIHTKENLCKCDICGKAFHYPLLLSQHKIVHTGKKPYKCENCDKSFHYPSKLSRHKKTHTGEKPYKCEVCG--------------KDFYYPSRLSKHKIVHTEENPYKCEVCGKAFDYPSRLSNHKK--------IHTEEKPY------KCEVCGKAFCFLSSLHKHKIIHTGEKPYKCDICGKAFGSPSRLSKNSKTHTGEKPYKCEVCGKAFHCPSILSVHKRIHTGEKPYKCEVCGKAFNIPSKLSHHNRIHTREKPYKC--EVCGKAFHYPSRLSKHKKIHTGGNPYNAEMCSKGFNYPSRLSEHKKLTTEEKPCKCEVCGKVFHFLSLLTIHKRIHTGEKPYKCEICGKDFHYPS-----------------LLSFFFFVFLFFFSFHFLLGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M9PGG2-1", "uniprot_id": "M9PGG2_DROME", "id": "M9PGG2-1", "name": "", "aln": "MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNPGAIGATPAQWGSEMYPNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQPQSPPGGGQEARDNGSGDGRQQQVSPSSSPYPSVQQQQRANGAGDEDPMNHQLANQQNPAPNQNQSSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQGGMLAPPGFPPLHYLNKGVLPMEQSGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGAGANGSGGVGGATGASVGVGSVGVTSGGRTGNGPGRP-HKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNTTKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQVANHLMNDAKSLAAQQFLNNNNPSAVDNKANILPVRSIASNAAAAAVVQQSVVKNELYFPQCYGPPFQHPFQAQQQQAQQPSVAHANGGPTPPVTVTVANSVASGVVVQQNASASVVAQXHPTTAATGAQQQQPSAPQQQHHPPPPPPTSTAHHIASAAAAVTAVTPSSAHASPVAAPQTVTLSITLPPPPASHTVHPGHPGHPGHPGVANGAAPPPPTLSHAIPIHPHIHSIFGSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ..: .. : * : **:: . :: . :: .: . :* :* :: . : .:: . . . :: : :. : . : . . : . : : .: *: .:. :: ::.* :.: . *. ::. :: : : * . : .. :. . .* . : : ..: :: *:. : :* *** *: * * *. ***. ..: *. *** *. * *::* **: *: * *.::*. *.:* :*:*.**: * :*.* *. : *.:* : * . .*: * : . :: : *.. . .:. .* :. * * :* :* *.* * : * * ** .:** * *** * *.*::: **.***: * * : *. : *. * :********** *** *. : * :*. * ::*: * * : * ..:::* * . :. : . : : . ::: :: : . . : . . : :: ", "identical_positions": 106, "similar_positions": 187, "identity": "11.29%" }, { "cls_id": "homologset.agr.HGNC:32462", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQK4-1", "uniprot_id": "A0A8I5ZQK4_RAT", "id": "A0A8I5ZQK4-1", "name": "Zinc finger protein 431-like", "aln": "------------------------MFQRTWKDALTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNWEDHTIEEHCQSFRRHGRHERCHTGEKPSE-------------------------------------------------------------------NTQCGKAFAQHSHLQRHKSTHTGEKLCECKPRDKAFTYD----------------------------SQLQTLERIHTGEKTYKCTQCGKAFERRCNFRRHKLIHSGRKSYKYNQCGKAFARLSHLKTHGITHTGEKPYKCDQCG-------------------KAFASHSYLQVHKREHTGEKPYECNQCGKAFVLHSALKTHERIHTGEKPYKCNQCGKAFARPSHLKRHGITHTGEKPYECEQCGKAFISCSYLQVHKRIHTGEKPYECDQCGKAFIRCSH---------------------------LQVHKREHTGEK-----------------------------PYECNQCGKAFVLHSDLKRHKR-----------------------------------------------------------------IHTGEKPYKCNQCGKAFARPSHLKRHGITHTGEKPYECEQCGKAFTSHSYLQRHKRIHTGEKPYKCNQCGKAFARPSHLKRHGITHTGEKPYECEQCGKAFTSH----------------------------SYLQVHQRIHTGEKPYVCDQCGKDFAYHSYLQVHKRIHSEEKPYVCDRC----------------------------DKAFAYHSYLQVHERIHNGENLYECDQCGKAFASHSSLRVHKRIHTGEKPYECNQCGKAFVGQSK------------------LKRHERIHTGEKPYKCNECGKAFVCNAYLRKHKATHTTVKPCECK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y7I7-1", "uniprot_id": "A0A8I5Y7I7_RAT", "id": "A0A8I5Y7I7-1", "name": "", "aln": "-----------------------MRMEFDTKDALTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNWEDHSFEEHCQSFRRYGRHERCHTGEKPSE-------------------------------------------------------------------NTQCGKAFAQHSHLQRHKSTHTGEKLYECKPRDKAFTYD----------------------------SQLQTLERIHSGEKPYKCNQCGKTFERRCNLGRHKLIHTGRKSYKCNQCGKAFARHSHLKLHGITHTGEKPYECDQCG-------------------KAFASHSYLQVHKTIHTGEKPYVCDQCGKAFAHSRPLRRHKIMHTRKKTYKCNQGGKAFARHSHLKTHGVTHTGEKPYKCDQCGKAFASHRYLQVHKRIHTGEKPYECDQCGKAFASHSH---------------------------LQVHRITHTGEK-----------------------------PYKCDQCGKAFAYHSYLQVHKR-----------------------------------------------------------------IHTGEKPYVCDQCGKAFAHLRHLQVHGITHTGEKPYKCDQCGKAFTSHSYLQVHKRIHTGEKPYVCDQCGKAFAQLSHLQVHGITHTGEKPYKCDQCGKAFSSH----------------------------SYLQVHKRIHTGEKFYECDQCGKAFASHSHLQVHKRIHTGEKPYVCDQCGKDFVVQRDLKRHKRTHTGEKPYKCNECGKAFVWNGSLRAHKVIHTGEKPYKCNECGKAFACNTSLRTHKAIHTGVKPFKCKQCGKAFVGQNY------------------LKKHERIHTGEKLYECNECGKAFVFDASLRKHKAVHTGVKP-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AEQ1-1", "uniprot_id": "A0A8I6AEQ1_RAT", "id": "A0A8I6AEQ1-1", "name": "", "aln": "------------------------------MDVLTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNWEDHTIEEHCQSFRRHGRHERCHTGEKPSE-------------------------------------------------------------------NTQCCKAFAQHSPLQRHKSTHTGEKLYECKSRDKAFTYY----------------------------SQLQTLERIHAGEKPYKCNQCGKAFTSHSSLQVHERIHTGEKPYKCNQCGKAFAQLSHLKTHGITHSGEKPYECEQCG-------------------KAFTSHSYLQVYKRIHTGEKLYECDQCGKAFVLHNALKRHKRIHTGEKLYECDQCGKAFAYHSYLQVHKRIHTGEKPYKCNQCGKAFAQLSHLKTHGITHTGEKSYECNQCGKAFTSHSY---------------------------LQVHKRIHTGEK-----------------------------LYECDQCGKAFVLHSTLKRHKR-----------------------------------------------------------------IHTGEKLYECDQCGKAFTSHSYLQVHKRIHTGEKLYECDQCGKAFVLHSALKRHKRIHTGEKLYECDQCGKAFAYHSYLQVHKRIHTGEKPYVCDRCDKAFAYQ----------------------------SYLQVHKRIHTGEKPYVCDRCDKAFAYHSYLQVHKRIHTRENLYECDQCGKAFTSHSSLQVHKRIHTGEKPYVCDQCGKDFVVPSDLKRHKRTHTEEKLYKCNECGKAFVCNASLRKHKATHTGVKPFDCKQCGKAFVGQND------------------LRRHERIHTGEKPYECNECGKAFSQSSQLQLHKRTHTY--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AWV7-1", "uniprot_id": "A0A8I6AWV7_RAT", "id": "A0A8I6AWV7-1", "name": "", "aln": "------------------------MSSLPAEDAVTYNDVHVNFTWEEWALLDPSQKNLYKDVMLETYRNLTAVGCSWKEHNIEERCQSSRRHGRHEKSPTEEKSSE-------------------------------------------------------------------YTQCGKAFACHSYPEMHERIHSGEKLYEDIQYGEAVVHH----------------------------SGLQIQKRTHTRENPYKCNQCDKAFANYGQLQRHERTHTRKKPYQCNECGKAFAYLSIIQMHKRTHTGEKPYKCNQCG-------------------KAFAYLSSFQMHKRTHTREKPYKCNQCGKAFAYLSSFQMHKRIHTGEKPCKCNQCGKAFAHYSTLQKHKITHTGEKPYECNQCGKAFARQSNLQGHKRTHTGEKPYECNQCGKAFARQSH---------------------------LQVHKRTHTGEKPYKCNQCGKAYKCRSSVNNHKIMTYSGQKPYECNQCGKAFVYHCILRKHKRTHTREKSYKLN----------QCGKTYKFNGLQNHKTTDTGEKLYECNECGKAFPHLHRLKRHERIHTGEKPYKCNECGKAFAYRSSLPKHKRTHTGEKPYKCNYCGKAYSQHSNLKTHKRIHTGEKPYECNQCGKAFALKSHLQVHKRTHTGEKPYKCNQCGKAFARQ----------------------------SYLQGHRRTHTGEKPYKCNQCGKVFAYPGYLQVHKRTHTGEKPYKCNQCG----------------------------KAFPCVRECKRHERIHTGEKPYKCNECGKAFGYHTSLQIHKATHSGKKPYECKQCNKAFAHHSQ------------------LQRHERIHTGEKPYKCNQCDKAFAQHNSLQIHKIIHTGEKPYECNQCGKAFAYHGYLQIHKRLHTGEKPYECNQCGKAFASQSDLKKHERIHTGKKPYKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZMG7-1", "uniprot_id": "A0A8I5ZMG7_RAT", "id": "A0A8I5ZMG7-1", "name": "", "aln": "MQIPEDLEKVWPWTGSLGREPLVPSAHANAKDAVTYDDVHVNLTREEWALLDPSQKSLYKDVMLETYRNLTAIGYNWEYHNIEEHCQSSRRHRRHESR-TGEKPSE-------------------------------------------------------------------YTQCGKAFTCHSYRQRHERINTGEKPYEGSQYDEAFVYH----------------------------SIRQIHKRIHTREKPYKCNRCDKAYLQHSHLQR----------------------------HKRAHTGERPYECKQCG-------------------KAFAYHSELQSHERIHTGEKPYRCNQCGKAFAHHCNLRVHKIIHTGEKPYKCNQCDKAYSQHCNLQIHKSTHTGEKSYKCNQCGKAFVYYGHLQRHKTTHTGEKPYKCNLCDKAFASHRY---------------------------LQVHKRTHTGEK-----------------------------PYECNQCGKAFVY-------------------------------------------------------------------------------------------------------------------------HDHLQIHKRTHTGEKPYECNQCGKTFAAHRYLQVHKRTHTGEKPYECNQCGKAFASH----------------------------SYLQVHKRIHTGEKPYECNQCGKAFAYPGYLQVHKRTHTGEKPYECNQCG----------------------------KAFAGQNVLKRHERIHTGEKPYKCNECGKAFVCNTSLHIHKATHTGEKPYECKQCGKAFASHGQ------------------LQSHEIIHTGEKPYKCNGCDKAYSRHSHLQRHKRTHTMNVTNVVEPLQVTVIFKGVVV------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AAI8-1", "uniprot_id": "A0A8I6AAI8_RAT", "id": "A0A8I6AAI8-1", "name": "", "aln": "------------------------------MSAVTYDDVHVSFTREEWALLDPSQKNLYKDVMVETYSNLTAIGYNWEDHNIEEHCQSSRRHARHERSTTGEKPCKGIQYGESFLHS------SLQIHKRTRTREKPYK----------------------------------CNRCDKAFSHHSYLQIHKRAHTGEKPYECNQCDKAYSRY----------------------------SYLQIHKRTHTGEKPYECKQCTKAFACHGQLRRHERIHTGEKPYKCNQCDKAFSRQSHLQIHKRTHTGEKPYECHQCG-------------------KAFVCSSHLQIHKRTHTGERPYECNQCGKAFLCHSSLRIHKRIHTGEKPYECNQCGKAFASISSLQYHKRTHSGEKPYKCNQCGNSYSQPCILKSHKRTHSGQKPYKCNQCDKAFACHSS---------------------------LQSHERTHTGEK-----------------------------LYECKQCGKAFTYHGGLQIHER-----------------------------------------------------------------THTGEKPYGCNQCDKAFACHSSLQNHKRTHTGEKPYQCNQCGKAFAYHNYLRIHKRTHTGEKPYECSQCGKAFSCHSTLQNHKRTHTGEKPYECNQCGKAFACF----------------------------SNLQNHKRTHTGEKPYECNQCGKAFACHNALQNHKRTHTGEKPYECDQCGKFYSNLHNLRIHKITHTGEKPYECDQCGKAFAYHGYLQIHKRTHTGEKPYECNQCGKAFAYHSNFRNHKRRHTGEKPYECNQCGKAFACHNS------------------LQNHKRTHTGEKPYECDQCGKAFAYHNYLQIHKKKHTGEKPYKCNQCSKAFACYSTLQNHKRMHTGEKPYECSQCGKAFSQPINLQKHKRKHTGETLEI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "K7N769-1", "uniprot_id": "K7N769_MOUSE", "id": "K7N769-1", "name": "", "aln": "------------------------------MDAMTFDDVHVNFTKEEWNLLEPSQMNLYKDVMLETYWNLTSIGYKWEDHHIEEPCQSSRRHTRHVRS-----------------------------------------------------------------------------------------------HSWKKLYECNQCGKAFTSH----------------------------SSLRYHKRTHTGEKPYECNHCGKAFARPAHLQR----------------------------HKRTHTGEKPYECNQCS-------------------KAFSCHSGLRYHKRTHTGEKPYECNQCGKAFARPADLQCHKRTHTGEKPYECNQCGKAFARPANLQCHKRTHTGEKPYECNQCGKAFSCQGGLRYHKRTHTGEKPYECNQCGKAFARPSH---------------------------LQCHKRTHTGEK-----------------------------PYECNQCGKAFSS-------------------------------------------------------------------------------------------------------------------------HISLRYHKRTHTGEKPYECNQCGKAFSGHSGLRYHKRTHTGEKPYECNQCGKAFATP----------------------------SHLQCHKRTHTGEKPYECNQCSKAFARPAHLQHHKRTHTGEKPYECNQCG----------------------------KAFARLSHLQCHKRTHTGEKPYECNQCGKAFSCHNSLRYHKGTHTGEKPYECNQCGKALATSTH------------------LQCHKRTHTGE-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARR7-1", "uniprot_id": "A2ARR7_MOUSE", "id": "A2ARR7-1", "name": "", "aln": "------------------------------MDLVTYDDVQVNFTQEEWALLDPSQKSLYKDVMLETHRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPSE-------------------------------------------------------------------FIQCGKAFAYESHSQRYEIKHTGEKHHDCNQCGKAFARS----------------------------DDLQKHKRTHTGEKPYKCNQCGKSFARSGDLQKHKR----------------------------THTGEKPYECNQCG-------------------KAFARNCDLQKHKRTHTGEKPYECNQCGKAFARKCDLQKHKRTHTGEKPYECKQCGKAFAESSTLQIHKRTHTGEKPYECNQCGKAFKRSSDLQKHKRTHTGEKPYECKQCGKAFAESST---------------------------LQIHKRTHTGEK-----------------------------PYECNQCGKAFKR-------------------------------------------------------------------------------------------------------------------------SCELQKHKRTHTGEKPYECNQCGKAFKRSCELQKHKRIHTGEKPYKCNQCGKAFTQS----------------------------SHLQIHKRTHTGEKPYECNQCGKAFARNCDLQKHKQTHTGEKPYECNQCG----------------------------KAFARKCDLQNHKQKHTGEKPYECKQCGKAFAQSSHLRIHKRTHTGEKPYECNQCGKAFKRRSD------------------LQVHKRTHTGEKPYKCKQCGKAFARSGGLQKHKRTHTGERPNECN-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARX0-1", "uniprot_id": "A2ARX0_MOUSE", "id": "A2ARX0-1", "name": "", "aln": "------------------------------MDLVTYDDVQVNFTQEEWALLDPSQKSLYKDVMLETYRNLKAIGYIWEGHTSEDHFQTSRSHGRHERSCTAVKPSE-------------------------------------------------------------------FIQCGKAFAYQSLRQRHERTHKGEKDYYCNQCGKAFIISSHLQIHKRRNTGEKPYECNQCCKTCTVRSDLQIHKQTHTGEKPYECNQCGKAFAGSGDFQKHKRRQRGEKPYECNQCGKTFAVRSDLRIHKRTHTGEKPYECKQCS-------------------KAFIRRGDLQIHKRTHTGEKPYECNQCGKAFIRSADLQIHKRTHTGEQPYECNQCGKAFIRSGDLQIHKRIHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFIRSGD---------------------------LQIHKRTHTGEK-----------------------------PYECNQCGKAFIR-------------------------------------------------------------------------------------------------------------------------SGDLQIHKRTHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFTKS----------------------------SNLQIHERTHTGEKPYECKQCGKAFIRSGDLQIHKRTHTGEQPYECNQCG----------------------------KAFIRSGDLQIHKRTHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFIRSGD------------------LQIHKRTHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECNQCGKAFIHSGNLKRHKRTHTGEKLYEGI---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P6H7-1", "uniprot_id": "A0A1W2P6H7_MOUSE", "id": "A0A1W2P6H7-1", "name": "", "aln": "------------------------------MDAVTYEDVHVNFSHEEWALLDSSQKSLYRDVMLETYWNLTAIGYKLEDPNVEEYYQSYRRHRRYNICHCGYKPCEHKG----------------------------------------------------------------YGKNQYIFACNNFLQIYDRIQTEEKPYRCSQCSKAFANF----------------------------RSLRKHEKNHTREKPYECSQCSKAFVSRSSLQIHERTHTREKLYDCNECGKAFSTRSHLQIHKRTHTGEKPYDCSECG-------------------KAFARSSTLLIHKRSHTGEKPYGCNECGKAFACRSHLQIHKRTHTGEKPYDCDECGKAFATRRHLQIHERTHTGEKPYECNQCGKAFIGRSHLQIHKRVHTGEKPYECNQCGKAFAYNSD---------------------------LHRHEIIHTGEK-----------------------------PYGCNQCGKAFAN-------------------------------------------------------------------------------------------------------------------------RSSLRNHEEHHTLEKPYECTLCGKAFAYCSNLYIHERCHTGEKPYVCTQCGKAFARRSHLHIHERCHTGEKPYVCTQCGKAFARCSHLHVHERIHAGEKPYECNQCGKAFLLRSSLLIHERTHTGEKPYVCNQCG----------------------------KAFARQSHLQIHERSHTGEKPYECNQCSKAFVCRSNLQMHERTHTGERPYECNQCGKAFSRRSL------------------LQKHERSHSGEKPYACNQCGKAFASRSSLRNHEKHHNIEKPNECNQCAKAFTSFPPSSNI----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A4K5-1", "uniprot_id": "A0A8I6A4K5_RAT", "id": "A0A8I6A4K5-1", "name": "", "aln": "------------------------------MDAVTYEDVHVNFSHEEWALLDPSQKSLYRDVMLETYWNLTVIGHKLEDHNVEEYCQRYRRHRRYNICHCGYKPCEHRG----------------------------------------------------------------YGKNQYIFACNNFLQIYDRIQTEEKPYGCNQCSKAFANF----------------------------RSLRKHEQNHTREKPYECSQCSKAFPSRSSLQIHERTHTGEKPYDCNECGKAFSTRSHLQIHKRTHTGEKPYDCNECG-------------------KAFARSSNLQIHKRSHTGEKPYDCNECGKAFACRSHLQIHKRTHTGEKPYDCDECGKAFATRSHLQIHERTHTGEKPYKCNQCGKAFIGRSHLQIHKRVHTGEKPYECNQCGKAFAYNSD---------------------------LHRHEIIHTGEK-----------------------------PYGCNQCGKAFAS-------------------------------------------------------------------------------------------------------------------------RSSLRNHEEHHTLEKPYECTLCGKAFAFCSNLYIHARCHTGEKPYVCTQCGKAFARR----------------------------SHLHIHERIHAGEKPYECNQCGKAFLLRSSLQIHERTHTGEKPYVCNQCG----------------------------KAFARQSLLQIHERSHTGEKPYACNQCSKAFVCRSSLQMHERTHTGEKPYECNQCGKAFTRRSL------------------LQKHERSHSGEKPYECNQCGKAFASRSSLRNHEKHHTIEKPNEYNQCAKAFTSLLPSSNI----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNF4-3", "uniprot_id": "ZN726_HUMAN", "id": "A6NNF4-3", "name": "Zinc finger protein 726", "aln": "------------------------------MGLLTFRDVAIEFSLEEWQCLDTAQKNLYRNVMLENYRNLAFLGIAVSKPDLIICLEKEKEPWNMKRDEMVDEPPGICPHFAQDIWPEQGVEDSFQKVILRRFEKCGHE----------------------------------NLQLRKGCKSVDECKVHKEGYNGLNQCFTTTQGKASQCG-------------------KYLKVFYKFINLNRYKIRHTRKKPFKCKNCVKSFCMFSHKTQHKSIYTTEKSYKCKECGKTFNWSSTLTNHKKTHTEEKPYKCEEYG-------------------KAFNQSSNYTTHKVTHTGEKPYKCEECGKAFSQSSTLTIHKRIHTGEKPCKCEECGKAFSQPSALTIHKRMHIGEKPYKCEECGKAFVWSSTLTRHKRLHSGEKPYKCEECAKAFSQFGH---------------------------LTTHRIIHTGEK-----------------------------PYKCEECGKAFIWP-------------------------------------------------------------------------------------------------------------------------STLTKHKRIHTGEKPYKCEECGKAFHRSSNLTKHKIIHTGEKPYKCEECGKAFIWS----------------------------SNLTEHKKIHTREKPYKCEECSKAFSRSSALTTHKRMHTGEKPYKCEECG----------------------------KAFSQSSTLTAHKIIHTGEKPYKCEECGKAFILSSTLSKHKRIHTGEKPYKCEECGKTFNQSSN------------------LSTHKIIHTGEKPYKCEECGKAFNRSSNLSTHKIIHTGEKPYKCDECGKSFIWSSTLFKHKRIHT-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZTI4-1", "uniprot_id": "A0A8I5ZTI4_RAT", "id": "A0A8I5ZTI4-1", "name": "", "aln": "------MIGLMCFDVGCRVSYGRAGNLLSRDMTVTFEDVHVNFTQEEWALLDPFQKKLYKDVMLETYRNLNAIGFNWEEQNIEEHCQRSRRQKRYFLYASSYKYASEEILMCAESLKVKQQCMKEVRVQRFPPNILTVENPLLYMLTVILKGMKGSIQKRSPLKLFSVLKPLLLTQVSKYIKEHKLDRNLMDVVNVVKFFQITVNLKSMKVFILKRNPTSIMNVIKPIHDPVASRCIKEFILERNPTNVMNVIKPFQTTVASRSIKEFTLERNTTNVMNVIKHFQYTVASRRIKEFTLDRNPTNVMNVIKPFHDPVDSSSINIFTLERNPTSVMNVIKPFHNTIAYGSIKEIILERNPTNVMNVIKPFQTTVASSRIKEITTEKNPTNVMNVIKPFHDPVTSRHIKVFTLERNPTNVMNVIKPFHDPVASRSIKEFTLERNPTNVMNVIKPFQTTVASSRIKEFTLERNPTNVMNVIKPFQTTVASSRIKEFTLERNPTNVVNVIKPFQKPVASRSIKEFTLERNPTNVMNVIKPFQYTVTSGSIKEFTLERNPTNVMNVIKHFHDTVASRHIKEFTLERNPTNVMNVIKPFHDLVASRSIKEFTLLRNPTNVMNVIKHFQYTVASRRIKEFTLERNPTNVMNVIKPFHDPVDSSSINMFTLERNPTNVMNVIKPFRNTVASRCIKEFTLERNPTNVMNVVKPFQDTVTSRSIKEFTLERNPTNVMNVIKPFQKSVASRSIKEFTLERNPTNVMNVIKPFQYTVTSGSIKEFTLERNPTNVMNVIKPFQTTVASRHIKEFTLERNPTNVMNVIKPFQDPVASRHIKEFTLERNPTNVMNVIKPFHDPVASRSIKEFTLERNPTNVMNVIKPFHDAVASRSIKEFTLERNPTNAMNVIKPFHDPVDSSTIKLHTGQKPYKCNECFEAFSEHSSLQMQKRIHTGEKPYKCNECDKAFSYHTSLQNHSRIHTIAKP-------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: ** :.:: *** *:. * .**::** *.: ** :* . : : . . : :: . :.:: . . :: . . :*:. . *.* : .. : *.* : * :: . : *.: .:. : : :.: .:. : *.* : .* *: : *.* . . * : ..: : . **: .::: : . * : . : . . : : . : : . : : ..::: . :*:. ..::: *:*: ", "identical_positions": 36, "similar_positions": 112, "identity": "3.59%" }, { "cls_id": "homologset.agr.HGNC:32463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQK4-1", "uniprot_id": "A0A8I5ZQK4_RAT", "id": "A0A8I5ZQK4-1", "name": "Zinc finger protein 431-like", "aln": "-----------------------------------------------------------MFQRTWKDALTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNWEDHTIEEHCQSFRRHGRHERCHTGEKPSE----------------------------------------------------------------------NTQCGKAFAQHSHLQRHKSTHTGEKLCECKPRDKAFTYD----------------------------SQLQTLERIHTGEKTYKCTQCG-------------------KAFERRCNFRRHKLIHSGRKSYKYNQCGKAFARLSHLKTHGITHTGEKPYKCDQCGKAFASHSYLQVHKREHTGEKPYECNQCGKAFVLHSALKTHERIHTGEKPYKCNQCGKAFARPSHLKRHGITHTGEKPYECEQCGKAFISCSYLQVHKRIHTGEKPYECDQCGKAFIRCSH---------------------------LQVHKREHTGEK-----------------------------PYECNQCGKAFVLHSDLKRHKR-----------------------------------------------------------------IHTGEKPYKCNQCGKAFARPSHLKRHGITHTGEKPYECEQCGKAFTSHSYLQRHKRIHTGEKPYKCNQCGKAFARPSHLKRHGITHTGEKPYECEQCGKAFTSH----------------------------SYLQVHQRIHTGEKPYVCDQCGKDFAYHSYLQVHKRIHSEEKPYVCDRC----------------------------DKAFAYHSYLQVHERIHNGENLYECDQCGKAFASHSSLRVHKRIHTGEKPYECNQCGKAFVGQSK------------------LKRHERIHTGEKPYKCNECGKAFVCNAYLRKHKATHTTVKPCECK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y7I7-1", "uniprot_id": "A0A8I5Y7I7_RAT", "id": "A0A8I5Y7I7-1", "name": "", "aln": "----------------------------------------------------------MRMEFDTKDALTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNWEDHSFEEHCQSFRRYGRHERCHTGEKPSE----------------------------------------------------------------------NTQCGKAFAQHSHLQRHKSTHTGEKLYECKPRDKAFTYD----------------------------SQLQTLERIHSGEKPYKCNQCG-------------------KTFERRCNLGRHKLIHTGRKSYKCNQCGKAFARHSHLKLHGITHTGEKPYECDQCGKAFASHSYLQVHKTIHTGEKPYVCDQCGKAFAHSRPLRRHKIMHTRKKTYKCNQGGKAFARHSHLKTHGVTHTGEKPYKCDQCGKAFASHRYLQVHKRIHTGEKPYECDQCGKAFASHSH---------------------------LQVHRITHTGEK-----------------------------PYKCDQCGKAFAYHSYLQVHKR-----------------------------------------------------------------IHTGEKPYVCDQCGKAFAHLRHLQVHGITHTGEKPYKCDQCGKAFTSHSYLQVHKRIHTGEKPYVCDQCGKAFAQLSHLQVHGITHTGEKPYKCDQCGKAFSSH----------------------------SYLQVHKRIHTGEKFYECDQCGKAFASHSHLQVHKRIHTGEKPYVCDQCGKDFVVQRDLKRHKRTHTGEKPYKCNECGKAFVWNGSLRAHKVIHTGEKPYKCNECGKAFACNTSLRTHKAIHTGVKPFKCKQCGKAFVGQNY------------------LKKHERIHTGEKLYECNECGKAFVFDASLRKHKAVHTGVKP-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AEQ1-1", "uniprot_id": "A0A8I6AEQ1_RAT", "id": "A0A8I6AEQ1-1", "name": "", "aln": "-----------------------------------------------------------------MDVLTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNWEDHTIEEHCQSFRRHGRHERCHTGEKPSE----------------------------------------------------------------------NTQCCKAFAQHSPLQRHKSTHTGEKLYECKSRDKAFTYY----------------------------SQLQTLERIHAGEKPYKCNQCG-------------------KAFTSHSSLQVHERIHTGEKPYKCNQCGKAFAQLSHLKTHGITHSGEKPYECEQCGKAFTSHSYLQVYKRIHTGEKLYECDQCGKAFVLHNALKRHKRIHTGEKLYECDQCGKAFAYHSYLQVHKRIHTGEKPYKCNQCGKAFAQLSHLKTHGITHTGEKSYECNQCGKAFTSHSY---------------------------LQVHKRIHTGEK-----------------------------LYECDQCGKAFVLHSTLKRHKR-----------------------------------------------------------------IHTGEKLYECDQCGKAFTSHSYLQVHKRIHTGEKLYECDQCGKAFVLHSALKRHKRIHTGEKLYECDQCGKAFAYHSYLQVHKRIHTGEKPYVCDRCDKAFAYQ----------------------------SYLQVHKRIHTGEKPYVCDRCDKAFAYHSYLQVHKRIHTRENLYECDQCGKAFTSHSSLQVHKRIHTGEKPYVCDQCGKDFVVPSDLKRHKRTHTEEKLYKCNECGKAFVCNASLRKHKATHTGVKPFDCKQCGKAFVGQND------------------LRRHERIHTGEKPYECNECGKAFSQSSQLQLHKRTHTY--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AWV7-1", "uniprot_id": "A0A8I6AWV7_RAT", "id": "A0A8I6AWV7-1", "name": "", "aln": "-----------------------------------------------------------MSSLPAEDAVTYNDVHVNFTWEEWALLDPSQKNLYKDVMLETYRNLTAVGCSWKEHNIEERCQSSRRHGRHEKSPTEEKSSE----------------------------------------------------------------------YTQCGKAFACHSYPEMHERIHSGEKLYEDIQYGEAVVHH----------------------------SGLQIQKRTHTRENPYKCNQCD-------------------KAFANYGQLQRHERTHTRKKPYQCNECGKAFAYLSIIQMHKRTHTGEKPYKCNQCGKAFAYLSSFQMHKRTHTREKPYKCNQCGKAFAYLSSFQMHKRIHTGEKPCKCNQCGKAFAHYSTLQKHKITHTGEKPYECNQCGKAFARQSNLQGHKRTHTGEKPYECNQCGKAFARQSH---------------------------LQVHKRTHTGEKPYKCNQCGKAYKCRSSVNNHKIMTYSGQKPYECNQCGKAFVYHCILRKHKRTHTREKSYKLN----------QCGKTYKFNGLQNHKTTDTGEKLYECNECGKAFPHLHRLKRHERIHTGEKPYKCNECGKAFAYRSSLPKHKRTHTGEKPYKCNYCGKAYSQHSNLKTHKRIHTGEKPYECNQCGKAFALKSHLQVHKRTHTGEKPYKCNQCGKAFARQ----------------------------SYLQGHRRTHTGEKPYKCNQCGKVFAYPGYLQVHKRTHTGEKPYKCNQCG----------------------------KAFPCVRECKRHERIHTGEKPYKCNECGKAFGYHTSLQIHKATHSGKKPYECKQCNKAFAHHSQ------------------LQRHERIHTGEKPYKCNQCDKAFAQHNSLQIHKIIHTGEKPYECNQCGKAFAYHGYLQIHKRLHTGEKPYECNQCGKAFASQSDLKKHERIHTGKKPYKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZMG7-1", "uniprot_id": "A0A8I5ZMG7_RAT", "id": "A0A8I5ZMG7-1", "name": "", "aln": "-----------------------------------MQIPEDLEKVWPWTGSLGREPLVPSAHANAKDAVTYDDVHVNLTREEWALLDPSQKSLYKDVMLETYRNLTAIGYNWEYHNIEEHCQSSRRHRRHESR-TGEKPSE----------------------------------------------------------------------YTQCGKAFTCHSYRQRHERINTGEKPYEGSQYDEAFVYH----------------------------SIRQIHKRIHTREKPYKCNRCD-------------------KAYLQHSHLQR----------------------------HKRAHTGERPYECKQCGKAFAYHSELQSHERIHTGEKPYRCNQCGKAFAHHCNLRVHKIIHTGEKPYKCNQCDKAYSQHCNLQIHKSTHTGEKSYKCNQCGKAFVYYGHLQRHKTTHTGEKPYKCNLCDKAFASHRY---------------------------LQVHKRTHTGEK-----------------------------PYECNQCGKAFVY-------------------------------------------------------------------------------------------------------------------------HDHLQIHKRTHTGEKPYECNQCGKTFAAHRYLQVHKRTHTGEKPYECNQCGKAFASH----------------------------SYLQVHKRIHTGEKPYECNQCGKAFAYPGYLQVHKRTHTGEKPYECNQCG----------------------------KAFAGQNVLKRHERIHTGEKPYKCNECGKAFVCNTSLHIHKATHTGEKPYECKQCGKAFASHGQ------------------LQSHEIIHTGEKPYKCNGCDKAYSRHSHLQRHKRTHTMNVTNVVEPLQVTVIFKGVVV------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AAI8-1", "uniprot_id": "A0A8I6AAI8_RAT", "id": "A0A8I6AAI8-1", "name": "", "aln": "-----------------------------------------------------------------MSAVTYDDVHVSFTREEWALLDPSQKNLYKDVMVETYSNLTAIGYNWEDHNIEEHCQSSRRHARHERSTTGEKPCKGIQYGESFLHSSLQIHKR-------------------------------------------TRTREKPYKCNRCDKAFSHHSYLQIHKRAHTGEKPYECNQCDKAYSRY----------------------------SYLQIHKRTHTGEKPYECKQCT-------------------KAFACHGQLRRHERIHTGEKPYKCNQCDKAFSRQSHLQIHKRTHTGEKPYECHQCGKAFVCSSHLQIHKRTHTGERPYECNQCGKAFLCHSSLRIHKRIHTGEKPYECNQCGKAFASISSLQYHKRTHSGEKPYKCNQCGNSYSQPCILKSHKRTHSGQKPYKCNQCDKAFACHSS---------------------------LQSHERTHTGEK-----------------------------LYECKQCGKAFTYHGGLQIHER-----------------------------------------------------------------THTGEKPYGCNQCDKAFACHSSLQNHKRTHTGEKPYQCNQCGKAFAYHNYLRIHKRTHTGEKPYECSQCGKAFSCHSTLQNHKRTHTGEKPYECNQCGKAFACF----------------------------SNLQNHKRTHTGEKPYECNQCGKAFACHNALQNHKRTHTGEKPYECDQCGKFYSNLHNLRIHKITHTGEKPYECDQCGKAFAYHGYLQIHKRTHTGEKPYECNQCGKAFAYHSNFRNHKRRHTGEKPYECNQCGKAFACHNS------------------LQNHKRTHTGEKPYECDQCGKAFAYHNYLQIHKKKHTGEKPYKCNQCSKAFACYSTLQNHKRMHTGEKPYECSQCGKAFSQPINLQKHKRKHTGETLEI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "K7N769-1", "uniprot_id": "K7N769_MOUSE", "id": "K7N769-1", "name": "", "aln": "-----------------------------------------------------------------MDAMTFDDVHVNFTKEEWNLLEPSQMNLYKDVMLETYWNLTSIGYKWEDHHIEEPCQSSRRHTRHVRS--------------------------------------------------------------------------------------------------HSWKKLYECNQCGKAFTSH----------------------------SSLRYHKRTHTGEKPYECNHCG-------------------KAFARPAHLQR----------------------------HKRTHTGEKPYECNQCSKAFSCHSGLRYHKRTHTGEKPYECNQCGKAFARPADLQCHKRTHTGEKPYECNQCGKAFARPANLQCHKRTHTGEKPYECNQCGKAFSCQGGLRYHKRTHTGEKPYECNQCGKAFARPSH---------------------------LQCHKRTHTGEK-----------------------------PYECNQCGKAFSS-------------------------------------------------------------------------------------------------------------------------HISLRYHKRTHTGEKPYECNQCGKAFSGHSGLRYHKRTHTGEKPYECNQCGKAFATP----------------------------SHLQCHKRTHTGEKPYECNQCSKAFARPAHLQHHKRTHTGEKPYECNQCG----------------------------KAFARLSHLQCHKRTHTGEKPYECNQCGKAFSCHNSLRYHKGTHTGEKPYECNQCGKALATSTH------------------LQCHKRTHTGE-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARR7-1", "uniprot_id": "A2ARR7_MOUSE", "id": "A2ARR7-1", "name": "", "aln": "-----------------------------------------------------------------MDLVTYDDVQVNFTQEEWALLDPSQKSLYKDVMLETHRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPSE----------------------------------------------------------------------FIQCGKAFAYESHSQRYEIKHTGEKHHDCNQCGKAFARS----------------------------DDLQKHKRTHTGEKPYKCNQCG-------------------KSFARSGDLQKHKR----------------------------THTGEKPYECNQCGKAFARNCDLQKHKRTHTGEKPYECNQCGKAFARKCDLQKHKRTHTGEKPYECKQCGKAFAESSTLQIHKRTHTGEKPYECNQCGKAFKRSSDLQKHKRTHTGEKPYECKQCGKAFAESST---------------------------LQIHKRTHTGEK-----------------------------PYECNQCGKAFKR-------------------------------------------------------------------------------------------------------------------------SCELQKHKRTHTGEKPYECNQCGKAFKRSCELQKHKRIHTGEKPYKCNQCGKAFTQS----------------------------SHLQIHKRTHTGEKPYECNQCGKAFARNCDLQKHKQTHTGEKPYECNQCG----------------------------KAFARKCDLQNHKQKHTGEKPYECKQCGKAFAQSSHLRIHKRTHTGEKPYECNQCGKAFKRRSD------------------LQVHKRTHTGEKPYKCKQCGKAFARSGGLQKHKRTHTGERPNECN-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARX0-1", "uniprot_id": "A2ARX0_MOUSE", "id": "A2ARX0-1", "name": "", "aln": "-----------------------------------------------------------------MDLVTYDDVQVNFTQEEWALLDPSQKSLYKDVMLETYRNLKAIGYIWEGHTSEDHFQTSRSHGRHERSCTAVKPSE----------------------------------------------------------------------FIQCGKAFAYQSLRQRHERTHKGEKDYYCNQCGKAFIISSHLQIHKRRNTGEKPYECNQCCKTCTVRSDLQIHKQTHTGEKPYECNQCG-------------------KAFAGSGDFQKHKRRQRGEKPYECNQCGKTFAVRSDLRIHKRTHTGEKPYECKQCSKAFIRRGDLQIHKRTHTGEKPYECNQCGKAFIRSADLQIHKRTHTGEQPYECNQCGKAFIRSGDLQIHKRIHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFIRSGD---------------------------LQIHKRTHTGEK-----------------------------PYECNQCGKAFIR-------------------------------------------------------------------------------------------------------------------------SGDLQIHKRTHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFTKS----------------------------SNLQIHERTHTGEKPYECKQCGKAFIRSGDLQIHKRTHTGEQPYECNQCG----------------------------KAFIRSGDLQIHKRTHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECKQCGKAFIRSGD------------------LQIHKRTHTGEKPYECKQCGKAFTKSSNLQIHERTHTGEKPYECNQCGKAFIHSGNLKRHKRTHTGEKLYEGI---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P6H7-1", "uniprot_id": "A0A1W2P6H7_MOUSE", "id": "A0A1W2P6H7-1", "name": "", "aln": "-----------------------------------------------------------------MDAVTYEDVHVNFSHEEWALLDSSQKSLYRDVMLETYWNLTAIGYKLEDPNVEEYYQSYRRHRRYNICHCGYKPCEHKG-------------------------------------------------------------------YGKNQYIFACNNFLQIYDRIQTEEKPYRCSQCSKAFANF----------------------------RSLRKHEKNHTREKPYECSQCS-------------------KAFVSRSSLQIHERTHTREKLYDCNECGKAFSTRSHLQIHKRTHTGEKPYDCSECGKAFARSSTLLIHKRSHTGEKPYGCNECGKAFACRSHLQIHKRTHTGEKPYDCDECGKAFATRRHLQIHERTHTGEKPYECNQCGKAFIGRSHLQIHKRVHTGEKPYECNQCGKAFAYNSD---------------------------LHRHEIIHTGEK-----------------------------PYGCNQCGKAFAN-------------------------------------------------------------------------------------------------------------------------RSSLRNHEEHHTLEKPYECTLCGKAFAYCSNLYIHERCHTGEKPYVCTQCGKAFARRSHLHIHERCHTGEKPYVCTQCGKAFARCSHLHVHERIHAGEKPYECNQCGKAFLLRSSLLIHERTHTGEKPYVCNQCG----------------------------KAFARQSHLQIHERSHTGEKPYECNQCSKAFVCRSNLQMHERTHTGERPYECNQCGKAFSRRSL------------------LQKHERSHSGEKPYACNQCGKAFASRSSLRNHEKHHNIEKPNECNQCAKAFTSFPPSSNI----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A4K5-1", "uniprot_id": "A0A8I6A4K5_RAT", "id": "A0A8I6A4K5-1", "name": "", "aln": "-----------------------------------------------------------------MDAVTYEDVHVNFSHEEWALLDPSQKSLYRDVMLETYWNLTVIGHKLEDHNVEEYCQRYRRHRRYNICHCGYKPCEHRG-------------------------------------------------------------------YGKNQYIFACNNFLQIYDRIQTEEKPYGCNQCSKAFANF----------------------------RSLRKHEQNHTREKPYECSQCS-------------------KAFPSRSSLQIHERTHTGEKPYDCNECGKAFSTRSHLQIHKRTHTGEKPYDCNECGKAFARSSNLQIHKRSHTGEKPYDCNECGKAFACRSHLQIHKRTHTGEKPYDCDECGKAFATRSHLQIHERTHTGEKPYKCNQCGKAFIGRSHLQIHKRVHTGEKPYECNQCGKAFAYNSD---------------------------LHRHEIIHTGEK-----------------------------PYGCNQCGKAFAS-------------------------------------------------------------------------------------------------------------------------RSSLRNHEEHHTLEKPYECTLCGKAFAFCSNLYIHARCHTGEKPYVCTQCGKAFARR----------------------------SHLHIHERIHAGEKPYECNQCGKAFLLRSSLQIHERTHTGEKPYVCNQCG----------------------------KAFARQSLLQIHERSHTGEKPYACNQCSKAFVCRSSLQMHERTHTGEKPYECNQCGKAFTRRSL------------------LQKHERSHSGEKPYECNQCGKAFASRSSLRNHEKHHTIEKPNEYNQCAKAFTSLLPSSNI----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R8G4-1", "uniprot_id": "M0R8G4_RAT", "id": "M0R8G4-1", "name": "", "aln": "MNSLPSWVQGSPSHRLLGNVVSLSMTSLNRTLLSVLPGSFCICVSPNSAAFLNLGQCGLCSAQDMEDLLSFTDVAIDFSADECECLEPAQWNLYKEVMLENYSNLVFLGLAFSKPYLVTFLEQSSDPWSMKR---------------------------------------------------------------------------------------------KASAAIHLGLKPHKCKECGKAFDRN----------------------------SVLIQHQRIHTGERPYKCDECG-------------------KSFNYSSSLKQ----------------------------HQRIHTGEKPYRCDVCGKAFNCSSYLGKHQRIHTGEKRYRCEECGKAFTNCSGLIVHRRVHTGEKPYKCEECGKAFSVRTTLSKHQRIHTGEKPYKCDECGKTFNVHSTLSKHQRIHTGEKPYKCEECGMAFNVRCI---------------------------LSKHQRTHTGEK-----------------------------PYKCKECGKAFNC-------------------------------------------------------------------------------------------------------------------------SSSLHQHQQIHRGEKLYKCDDCGQAFSCSSYLYKHRRIHTGMKPYKCKECGKAFYCS----------------------------VNLIYHQRVHTGEKPYKCNECGKAFSICSTFMKHQRIHSGEKPYKCKECE----------------------------KAFNNCYNLIQHQRIHTGEKPYKCKDCGKAFNYTSSLAQHERIHTGEKPYKCEECGKAFNSSSN------------------LKHHWRLHTGEKPYKCEQCGKAFKNCSGFTRHYRIHTRENPD----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16372-1", "uniprot_id": "ZFP58_MOUSE", "id": "P16372-1", "name": "Zinc finger protein 58", "aln": "-------------------------------------------------------------------MLSFWDVAIDFSPEERECLEPDQWDLYRDVMLENYSHLDFLGLALSKPFLVTFLEQRQGPWDVKR---------------------------------------------------------------------------------------------QAAAAVHPGKTVNKCKDFSKAFFCK----------------------------SLLTQHQRIRTGEKAFKCEECG-------------------KAFNNRSNLSE----------------------------HKRIHTGEKPYKCEECGKAFRIRSKLSTHQRVHTGEKPYKCEECGKAFNSHSNLSEHKRIHTGEKPYKCEECGKAFSTRSTYYRHQKNHTGKKPYKCEECAKEFSYPSLLKVHQRIHSAEKSYKCEECGKPFYCPLL---------------------------LKKHQIIHSAEK-----------------------------PYKCAECGKAFHY-------------------------------------------------------------------------------------------------------------------------PSLLKRHQRIHAGKKPCKCKDCDRAFYSSAFLKRHQRIHSEENSYKCGECGKRFCSF----------------------------PHLQYHQRFHSGEKPYKCEQCGKTFSTLSYLPWHKLRHSGEKSYKCEKCG----------------------------KMFYSTLDLKKHQKIH----EYKCGECHYGFPNYAALTAHQRVHTGEKPHVCEQCGKDFSRIDS------------------LNQHQLVHTGEKPYKCEKCGKCFYRSSSLKRHQGIHS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DKX0-1", "uniprot_id": "ZN728_HUMAN", "id": "P0DKX0-1", "name": "Zinc finger protein 728", "aln": "-----------------------------------------------------------------MGSLTFRDVAIQFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLGIAAPKPDLIIFLEQGKEPWNMKRHELVKEPPVICSHFAQDLWPEQGREDSFQKVILRRYEKCGHENLQLKIGCTNVDECKVHKKGYNKLNQSLTTTQSKVFQCGKYANIFHKCSNSKRHKIRHTGKKLLKCKEYVRSFCML----------------------------SHLSQHKRIYTRENSYKSEEHG-------------------KAFNWSSALT-----------------------------YKRIHTGEKPCKCEECGKAFSKFSILTKHKVIHTGEKHYKCEECGKAFTRSSSLIEHKRSHAGEKPYKCEECGKAFSKASTLTAHKTIHAGEKPYKCEECGKAFNRSSNLMEHKRIHTGEKPCKCEECGKAFGNFST---------------------------LTKHKVIHTGEK-----------------------------PYKCEECGKAFSW-------------------------------------------------------------------------------------------------------------------------PSSLTEHKRIHAGDKPYKCEECGKTFKWSSTLTKHKIIHTGEKPYKCEECGKAFTTF----------------------------SSLTKHKVIHTGEKHYKCEECGKVFSWSSSLTTHKAIHAGEKLYKCEECG----------------------------KAFKWSSNLMEHKRIHTGEKPYKCEECGKAFSKVANLTKHKVIHTGEKQYKCEECGKAFIWSSR------------------LSEHKRIHTGEKPYKCEECGKAFSWVSVLNKHKKIHAGKKFYKCEECGKDFNQSSHLTTHKRIHTGGKTLQM----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZTI4-1", "uniprot_id": "A0A8I5ZTI4_RAT", "id": "A0A8I5ZTI4-1", "name": "", "aln": "-----------------------------------------MIGLMCFDVGCRVSYGRAGNLLSRDMTVTFEDVHVNFTQEEWALLDPFQKKLYKDVMLETYRNLNAIGFNWEEQNIEEHCQRSRRQKRYFLYASSYKYASEEILMCAESLKVKQQCMKEVRVQRFPPNILTVENPLLYMLTVILKG---MKGSIQKRSPLKLFSVLKPLLLTQVSKYIKEHKLDRNLMDVVNVVKFFQITVNLKSMKVFILKRNPTSIMNVIKPIHDPVASRCIKEFILERNPTNVMNVIKPFQTTVASRSIKEFTLERNTTNVMNVIKHFQYTVASRRIKEFTLDRNPTNVMNVIKPFHDPVDSSSINIFTLERNPTSVMNVIKPFHNTIAYGSIKEIILERNPTNVMNVIKPFQTTVASSRIKEITTEKNPTNVMNVIKPFHDPVTSRHIKVFTLERNPTNVMNVIKPFHDPVASRSIKEFTLERNPTNVMNVIKPFQTTVASSRIKEFTLERNPTNVMNVIKPFQTTVASSRIKEFTLERNPTNVVNVIKPFQKPVASRSIKEFTLERNPTNVMNVIKPFQYTVTSGSIKEFTLERNPTNVMNVIKHFHDTVASRHIKEFTLERNPTNVMNVIKPFHDLVASRSIKEFTLLRNPTNVMNVIKHFQYTVASRRIKEFTLERNPTNVMNVIKPFHDPVDSSSINMFTLERNPTNVMNVIKPFRNTVASRCIKEFTLERNPTNVMNVVKPFQDTVTSRSIKEFTLERNPTNVMNVIKPFQKSVASRSIKEFTLERNPTNVMNVIKPFQYTVTSGSIKEFTLERNPTNVMNVIKPFQTTVASRHIKEFTLERNPTNVMNVIKPFQDPVASRHIKEFTLERNPTNVMNVIKPFHDPVASRSIKEFTLERNPTNVMNVIKPFHDAVASRSIKEFTLERNPTNAMNVIKPFHDPVDSSTIKLHTGQKPYKCNECFEAFSEHSSLQMQKRIHTGEKPYKCNECDKAFSYHTSLQNHSRIHTIAKP-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VDN4-1", "uniprot_id": "Q9VDN4_DROME", "id": "Q9VDN4-1", "name": "C2H2-type domain-containing protein", "aln": "------------------------MHLNHATAATAAMANYQHYQLPASHGGGGGGGGGGGGGGGSNGGSGPGPNSGQQQPTTLASLQQSPFALHQLTAVQAIQHPTHQAMLHPQHPLVHLLDISTTTANSGGGGGGSHTPIS------------------------------------------------------------------------PMKQEVQSVISEEEVVVDDPRKKKQCHVCKNKFRQL----------------------------TTLRNHMKIHTDERPYKCKHCD-------------------KAFRQISTLTN----------------------------HVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPQTGSGKHRKSQMHQAYQQQHQRVQISKTLYSGSYSSPAAEELVKPFQCSVCKRRFPQLSTLHNHERTHIDPKPYKCETCDKSFSQLAT---------------------------LANHKKIHTGDK-----------------------------PYTCSYCHMQFRQ-------------------------------------------------------------------------------------------------------------------------QSTLTNHLKTHTHQIAPGGVGGAGGGGGAVTATVDHSMPAPLAPGTQQLTSGLLPNN------------------------------LHGSTANIIQLDHHPLLHFLDGSTTVSSVVATAAANTKVEHFQAGGSP----------------------------SGRMTVVGTINMLKGDNPDRPFGCSVCQRFFSQQSTLVNHIKTHTGEKPYKCKICEVNFRQVAT------------------LNNHMKIHTGEKPYNCSFCPKQFRQKSTLQNHLRVHTC--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: *:: . : : . : . . . ..:: * : ..* * * . . : . . . . :. : . : :. : .* : .: :: * . . . : . . : : . : . : . : . . : *:*: ", "identical_positions": 10, "similar_positions": 59, "identity": "0.96%" }, { "cls_id": "homologset.agr.HGNC:32464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZD8-1", "uniprot_id": "A0A0G2JZD8_RAT", "id": "A0A0G2JZD8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMLSFRDVAIDFSAEEWECLDLAQWKLYRDVMLENYNNLVFLGLASCKPYLVTFLEQIQEPSDVKGRATTTMHPGG-------------------------------------------------------------------------------------------KCCTCKVCGRVFEWTKVFQNHQIIDLGVKGYECEECTKYTHIPSLLPEEKTIHTVEKPYKCEVCGKAFCIPLLLSKHKIIHTEENPYKCDLCGKAFQHPSRLSRHKKIHSGDKP-YKCEVCGKAFHFPSLLLVHKRIHTGEKPYKCEVCGKAFHYPSILSKHKRIHTGEKPYKCEVCGKAFHISSFLSKHKIIH------RGEKPYKCDVCGKAFHYPSRLSNHKKIHSG----EKPYKCEVCG--KAFRILSLLSKHKIIHTEENPYKCEVCGKAFDYPSRLSTHSKMHTEEKPYKCEACGKAFRSLSSLSKHRRIHTGDNYYNSEVCGKAFIYPLRLSKHKKICTGEKPYKCEVCG------KAFNDSLVLSKHRAIHTGEKLYKCDVCGKAFYYPSRLNNHRKIHSGEKP----------------------------YQCEECGKAFCFPSSLSKH---KRIHTGEKPYKCKECDKAFRSLSSLSKHRRIHTGEKPYKCEVCGKAFHYPSLLSKHKITHTEEKPYKCEVCGQGFHVPSKLSHHKIIHTGESPYKCEVCG------------------------------------------------------------------------------------KAFCIPLLLSKHKISHTGENHSNSQLSKKAFIYPS----------------------------RLSKHKKIHKRVKPYKCEVCGKAFRFPSLLLIHKGIHTGEKPYKCEECGKAFYYPSLLSKHKRVHTGEKPYQCEVCGKGFHVSSSLSKHRIIHTGEKPYKCEVCEKAFRFSSSLSKHKRIHTGKKPYKCEECGKAFHFPSLLSKHKISHTGEKPYNCDLCGKAFYYPSLLSKHKMIHTGE-KPHKCDICGKAFHYPSKLSNHKKIHTGEKPYKCEVCGNVFCFASSLSKHKRIHTGENPYKCDVCGKAFYYPSLLCHHKIIHTGEKPYKCEVCGKAFHYPSLLSKHKIIHTGKKPYKCEVCGKAFHYPSRLSKHKKIHGAGEMAQELRELATLSRS----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A1R7-1", "uniprot_id": "A0A8I6A1R7_RAT", "id": "A0A8I6A1R7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSFRDVAIDFSAEEYECLDPAQWKLYRDVMLENYSNLVFLGLASAKPYLVTFLEQTQEPSDVKGGTATIKHPVE-------------------------------------------------------------------------------------------KCCTCKECGKVFEWTKVFQNHQIIDLGVKGYKCEECTKYTHIPSLLPEEKTIHTVEKPYKCEVCGKAFCIPLLLSKHKIIHTGENPYKCDVCGKAFQHPSRLSRHKKIHSGDKP-YKCEVCGKAFHFPSLLLVHKRIHTGEKPYKCEVCGKAFHYPSILSKHKRIHTGEKPYKCEVCGKAFHISSFLSKHKIIH------RGEKPYKCDICGKAFHYPSRLSNHRKIHSE----EKPYKCEVCG--KAFRFLSLLSKHQIIHREENPYKCEVCGKAFDYPSRLSTHSKMHTEEKPYKCEACGKAFRSLSSLSKHRRIHTGDNYYNSEVCGKAFVYPSRLSKHK-ICTGEKPYKCEVCG------KAFHVASLLSKHRTVHTGEKLYKCDVCGKAFYYPSRLSNHKRIHTGEKP----------------------------YQCEVCGKAFCFPPSLSKH---KRIHTGEKPYKCKECGKAFRFPSSLSAHKKIHTGEKPYKCDVCGKAFHYPSLLSKHKIIHTGEKPYKCEVCGQAFHVASKLSHHKIIHTGEKPYKCEICGKAFHYSSLLSKHKIIHTGKKPYKCDICDKAFYYPSRLSSHTKMHTGEKPYKCEVCGKAFCSPSSLSKHKRIHKVEKAYSCEVCGKVFCIPLLLSKHKRIHLGESHCNSEICSMAFVYPSRLPKHKKNHTREKPYKCEVCGKAFDYPSRLSKHKKIHTRVKPYKCEVCGKAFHFVSLLLVHKGIHTGEKPYKCEECGKAFYYPSLLSKHKIIHTGEKPYQCEVCGKGFHVSSSLSKHRRIHTGEKPYKCEVCEKAFRFSSSLSKHKRIHTGKKPYKCEECGKAFHFPSLLSKHKISHTREKPYNCDLCGKAFYYPSLLSKHKMIHTGE-KPHKCDVCGKAFHYPSKLSNHKKIHTGEKPYKCDICGNVFRFPSSLSEHKRTHTGENPYKCEVCGKAFHVPSKLSHHKIIHTGEKPYKCEVCGKAFHYPSLLSKHKIIHTGKKPYKCEVCGKAFHYPSRLSKHKKIHGAREMSQGLRALVALPEILSSIPSNYIVAHNHL-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8JJX8-1", "uniprot_id": "B8JJX8_MOUSE", "id": "B8JJX8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVGAGSSAIFQEMLSFRDVAIDFSAEEWECLEPAQLDLYRDVMLENYSNLVFLGLASSKPYLVTCLEQIQEPSDVKRGAATSMLPER-------------------------------------------------------------------------------------------KCYKCKECGKVSEWTKVFQNHQMLDLGMNYYKCEECAKSFHSPSLSSEENRIHAGEKPYKCEVCGKAFCIPLLLSKHKIIHKGENLYKCEVCGKAFQHPSRLSRHKKIHSEEKP-YKCEVCGKAFHFPSLLLVHKRVHTGEKPYKCTVCGKAFHYPSIFSKHKRIHTGEKPYKCEECGKAFHISSFLSKHKIIH------RGEKPYKCEVCGKAFHYPSRLSNHKKIHSG----EKPFKCEVCG--KAFRILSLLSKHKIIHTEENPYKCEVCGKAFDYPSRLSNHAEMHTREKPYKCEVCQKAFRSLSSFSKHKRIHTKDNYYNSELCGKAFIYPSRLSKHKKICAGEKPYKCEVCG------KAFHVASLLSKHRTIHTGEKLYKCEVCGKAFYYPSRLSNHKKIHTGEKP----------------------------FQCEVCGKAFCFPSSLSKH---KRIHTGEKPYKCKECGKAFRSLSSLSKHKRIHTGEKPYKCEECGKAFHYPSLLSKHKIIHTGEKPYKCDICDQAFHVPSKLSHHKIIHRGEKPHKCEVCG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KAFHYPSRLSNHKKIHSEEKPYKCEVCGKAFRILS------------------------------------------------------------------------------------LLSKHKIIHTEE-NPYKCEVCGKAFDYPSRLSTHAKMHTREKPYKCEVCQNAFRSLSSLSKHKIIHKEEKPYKSDICGQAFHVPSKLSHHKIIQTGEKPYKCEVCGKAFCIPLLVSKHKRVHTGENPYNSQVYNKAFIYPLRLSKHKKICTKEKPYKC--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NN14-1", "uniprot_id": "ZN729_HUMAN", "id": "A6NN14-1", "name": "Zinc finger protein 729", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGAPGSLEMGPLTFRDVTIEFSLEEWQCLDTVQQNLYRDVMLENYRNLVFLGMAVFKPDLITCLKQGKEPWNMKRHEMVTKPPVMRSHFTQDLWPDQSTKDSFQEVILRTYARCGHKNLRLRKDCKSANEGKMHKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKT-YKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIH------TGEKPYKCEECGKAFKWSSKLTVHKVVHTG----EKPYKCEECG--KAFSQFSTLKKHKIIHTGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECG------KAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKH---KIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGE-KPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECAKAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TPY2-1", "uniprot_id": "A0AB32TPY2_DANRE", "id": "A0AB32TPY2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFIK----------EESEDVKIEETFTVKQED---------------------------------------------------------------------------------------------------------------------------LQEQT----------------------------------------DLIEENE-GRKEEEHHVKIEEKTHLQTDGILKRGDKNSFTCTQCGKSYGSKDYLKIHMMIHTGEKLFTCPQCGKSFGRKRELKIHKRIHTGEKPYTCTRCGKSFSQSSNLNQHMRIH------TGEKPFTCTQCGKSFNRSSSLNEHMMIHTG----EKPFTCTQCG--KSFGRNFDLKIHMMIHTGENPFRCTHCGKSFSQSSYLNQHMRIHTRENPFTCTQCGKSFHRSSSLNNHKTIHTR----------------------------EKPFTCTQCG------KTFNNSSHLYEHMRIHTGEKPFTCTQCGKSFSLSSNLNRHMRIHTREKP----------------------------FTCTQCGKSFICSSSLNLH---IMSHTGEKLALKQRSQWTFFPMDFHSYARECVRQETKFVCQVSQFTALQSSSLVNSDLQNRIT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9QDC4-1", "uniprot_id": "E9QDC4_DANRE", "id": "E9QDC4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFIK----------EESEDVKIEETFTVKQED---------------------------------------------------------------------------------------------------------------------------PQEQT----------------------------------------DLIEEYE-GSKQEEHHVKIEEKTHLQTDGVLKRRDKNRFTCTQCGRSFGRKGDLRIHMRIHTGEKISTCTQCGKSFGRKDHLKIHMMIHTGEKPFTCTQCGKSFSYSSHLNEHMRIH------TGEKPFTCTQCGKSFSHLSSLNQHIRIHTG----EKPFTCTQCG--KSFR----------------------------HSLILKQHIRIHTGEKPFTCTQCGKSFRQSSSLNYHKKIHTG----------------------------EKPFTCTQCG------KSFSQSSSFNQHMRIHTGEKPFTCTQCGKSFSQSSSFNYHMRIHTGEKP----------------------------FKCTQCGKSFRISTSLNLH---MMSHT----------------------------REKPFTCT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TT05-1", "uniprot_id": "A0AB32TT05_DANRE", "id": "A0AB32TT05-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMAFIK----------EESEDVKIEETFTVKQED---------------------------------------------------------------------------------------------------------------------------LQEQIGWFHSQTPTQ---------------------------SYRDLIKDYE-ESK-EEHHVKIEDKTHLVTDGILKVRDKSCLTCTQCGKSLASKSKLKTHMRIHTGEKPFTCYQYGKSFS-KSSLYRHKKIHTGKKTFTCTQCGKSFNCSSHLNQHIRIH------TGEKPFRCTQCGKSFNCSSHLNEHMMIHTG----EKPFTCTQCG--KSFSKSSSLYRHMKIHTGEKPYTCTECRKSFSQSSSLNLHMRIHTGEKPFTCTECGNSFSKSSSLYRHMKIHTG----------------------------EKPFTCTECG------KSFIQSSCLNVHMRIHTGEKPFTCTQCGKSFIHSSHLNQHLMIHTGEKP----------------------------FKCPQCGKSFSQS-YLKKH---MKIHTGVREYMCLECEKTFITAAELKRHKRIHTGEKPYKCSQCSKRFAHSGTLKAHQRIHTGDKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JE90-1", "uniprot_id": "A0AC58JE90_DANRE", "id": "A0AC58JE90-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTFIK----------EESEDVKIEETFTVKQED---------------------------------------------------------------------------------------------------------------------------LQEQTDLIVLKEETQ----------------------------HWNKMEEPHQEITADEKPTLTEKTSSLGRPRKSKT--ECNFSSKQRRKSFIQKRNLGDHMRVHTREKPYTCEQCGKSFGKKRSLKTHMRIHTGERPYTCQQCGKSFKQIGTLKGHMRIH------TGERPYTCQQCGKSFKQSATLKGHMRSHTG----ERPYTCQQCG--QSFY----------------------------YAGNFAAHKRIHTREKPYTCQQCGKSFKQSGTLKGHMRIHNG--------------------------------GKTQCG------KSFAQKQKLDTHMTIHTGEKPYTCTECGKSFTCKSSLINHMKTHTREKL----------------------------FACNQCGKSFTCKANLMNH---MDGHTGTIVFICDQCGKSLTRKDYIKQHMKTHSREDRFRCRECGKSFKQKINLSAHMKLHNAEQSPQH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7S6-1", "uniprot_id": "A0A0B4K7S6_DROME", "id": "A0A0B4K7S6-1", "name": "", "aln": "MSANRRRRSASAASSIAAETATAATAATAEAISTAPSKEQLSPPIAGGSASADEDLLEMPRICRCCCKRDLKLLGLFEASQPTLANTTVASASAAASVASNKSSGTLAKTCATEAETETPQTLSANPVNPGTKATSSPSEAATTLSTSTRPASASFSSTSFSTSTSPMRRRTTNTTAPSASPAPRGRSSDNAVDYTLSGAHSSMDIVLEEMTIWMLNINRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDFAQEISDRQTARQAKRQQKVQKKTHDRWLQLEPTSHEEQQPIRKRRMVSESDGDSTAAAAAAEAATATATTPAKQVRTDFESLPPPKPSPQQHRVRKYRTLSIDCEMERPAASINASSMPWKTKAARKELSENWASSCSTAVMSPNRQRSSTSSSEHMSDLSVGPCCGFESDSNPSSTSNSARRTVILVKQQSPEKTSPMYDLMPRRGRRPRKAPIYMPAKRQRRSLVRKEPLYRKAQPVNEENKKSDQKDIYPKESRMEGLAPSCDEAIDSTSDAPMEVASNVVQKKCDEICLNGLIDSRNQLGAMEMEPVNEMIASNGVDKELTLSVQNNKETTSEEQIFEATSVIKESVQPEQSAEDIQVRTEIESIANDIRAEADLVQSEELTSSTETSESQPKAVEQLESMGKQESYALPQNMEAHESVQQTQTVDESDSADQREIIVSIPLEVLDENLQRRLCVDPETEAANRQSADPKEFALRPDDVNNNENDENFCQSATADSFNSAVALRTNKIEATPPGGTDSDDTDTDEVPIVPSGPTPMDFMAEFAKHCANGIEQLKVTTPVPSPTPSDLVPLNDLEAKQKLEVEMNDVETTLNGILNEMQDQHMYTPNCAHIDEFLTPADYATLTEQESSVSSPPNPFEQSSVAEPKDEKPSATEDPFDNSNFTN-------------ELIGFQNDIPCFENIETPEEGQNLHLELTQFLRDLQPSQSDPPAGEQVEKIEMETQPSTVQMDVQSNLPVQAADTQPQNESANHSPFESPISSPQVQSQIELQMEPQIETQMQPQIETRMQHDVLSVQSPQNHQPQVQSHDQSQMQHQIPPQIEPQIEVQNQEQNTLQLVPQAQHQVVPHVQLQSQLVPHVQTQGTTTTVTYEQIYQQHIVQQTVQQSSNKMQVISLPSAGSETTRQWQTQQSQQQQQVQWSSVGGLEAIKSAPVESVAPTTTTYYISASDLYPQQTETYTMLQPASNESYVIEQVNHQQQHCQQQIQMSQQQHQRQHQQQQAQQQQQPIMILIQQPEIQQPVASASNPQQAPLHIYNAATSNDVHQMQHTQRQQIRQQYQHQQYQRLQQPQQTRVVQSHPVLG--MPGATSISTKVTPIPVTAARGRPLTLKCRFCHNGPRFSSSLEYSRHIIDLHPAVAPFNCPHCPMAFAGRTKRSQHILSHHVVQQYQCGQCSHVFPAQKALDVHIQRFHMTLKTDPSGAVKVEDVQLQITSERRPRGRPYKPRLQLQQHQLQPQQKLQVQQHQQQQKALQQLPQAQHHQQQQQPQLQQEVLQQVQQLQVQVQ--------------------------------PQQHQQHQQVLQVQQPQQQPLMQPQSPHPSTVEMQASPTTPRKILCCPDCEDCTSGHSHANEQFEELQTLQAPPTVLTPPSTIVSVPSPQPMVYSQHITMPSPEQSEPDSTTTLRQYRKRGVIVGPQGPLHLATPVASPSPSSSPSSSTVDHIPPASPATPASPAPPPSPAVASTVQVSELRTSHHCLYCEERFTNEISLKKHHQLAHGALTTMPYVCTICKRGYRMRTALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIKFHGELGYQCDGCDRTFEYLKELRKHRRTHS-EMFYKCKFCPSSFMRFTNFRAHMKTHLPLGVFRNEDAASKSPSNNNSHASSDKLENPATPIEETPLTPMSSGGHLYHSPDEYPNSVESCAGNSVALESYATTP---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::: : . . : * . : : ::: :: : . : . . . * * : *: : ::. : : : : . : . . : :* :* . : *: .. : : * ** .: : : . :: * * :. * *. : * ", "identical_positions": 15, "similar_positions": 58, "identity": "0.74%" }, { "cls_id": "homologset.agr.HGNC:32466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ARW3-1", "uniprot_id": "A2ARW3_MOUSE", "id": "A2ARW3-1", "name": "", "aln": "---------------------------------------------MNLITYDDVHVNFTQEEWALLDPSHKNLYKDVMVETYRNLTAIGYIWEEHTSEDHFQNSRSHGRHERSCSAEQ-----------------LSEFIHCGKAFAYESGSQRHQIKHTGEKHHDCNQCGKAFKRRSDIQIHKQTHTGEKPYECNQCGKAFAGSGDLQ------------------------------------------------------------------------------------------------------------KHKRTHTGEKPYKCNQCGKAFSQSSHLRIHKRTHTGEKPYECKQCGKAFAHSSHLHIHERTHTREKPYECKQCGKAFSQSSHLQIHKRTHTGEKPYECKQCGKAFAQSSHLRIHKQTHTGEKP------------------------------------------------------------------------------------YECKQCGKGFAGSGDLQKHKQTHTGEKPYECKQCGKAFSRKSDLQKHKRTHTGEKPYECKQCGKAFAQSSTLQIHKRTHTGEKPYECKQCGKAFAGSSGLQCHKRSHTGETPYECNQ--GGKPFEGSSGLEYNNRTQTAEKPYECNQCGKVFAGRSDL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WRJ1-1", "uniprot_id": "A0A087WRJ1_MOUSE", "id": "A0A087WRJ1-1", "name": "", "aln": "---------------------------------------------MDAVTYDDVHMNFTEEEWDLLDSSQKRLYEEVMLETYQNLTDIGYNWQDHHIEEHCQSSRRHERHERSHIGEK-----------------PYERNQCGKAFERYNHLQIHKRTHTRQKPYECNQCGKVLSCHRSLQYHKRTHTGEKTCECNQCGKAFIRPTQLQ------------------------------------------------------------------------------------------------------------THKRTHSGEKPYECNQCGKAFAVQYNFQKHKRIHTGEKPYQCNQCDKAFSQNCSLQYHKRTHTGEKPYECNQCGKAFAFQSSLQYHKRKHTGEKPYQCNQCGKAFAHHSSLQYHKIKHTGEKP------------------------------------------------------------------------------------CECTQCGKAFARPNELQNHKRTHTGEKPHECNQCGKAFAVQYNLQKHKRIHTGEKPYQCNQCDKAFSQKSNLQYHKRTHTGEKPYECNQCGKAFTAHCSLQIHKRMHTGEKPYQCNQ--CGKTFVHHTSLQYHKRIHFRKKP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5RM15-1", "uniprot_id": "A0A1D5RM15_MOUSE", "id": "A0A1D5RM15-1", "name": "", "aln": "---------------------------------------------MDALTYDDVHINFTPEEWALLDHTQRNLYTDVMLETYKNLVAIGYKPEDK-IIEHLQNFRIPGRHKGSLTREK-----------------PYEYTQCGKASTRHIGLQRHERIHTGEKPYKCNQCGKAFVDYCTLQKHERTHTGEKAYECNECGKGFTQQAYLQ------------------------------------------------------------------------------------------------------------NHKRTHTGEKPYECYECGKGFAHYSTLRKHGSTHTGEKPYECNECGKAFAQQSHLQNHKRTHTGEKPYECNECGKAFSQHSSLQNHKRTHTGEKPYECNECGKAFSQYSNLRKHKRTHTGEKP------------------------------------------------------------------------------------YECNECGKAFSQHSSLQQHKRTHTGEIPYECNECGKAFSQHSSLQMHKRTHTGEKPYECKQCGKAFSQHSSLRKHKRTHTGQKPYECSQCGKAFSRHSSLQQHKRTHTGEKPYECNE--CGKAFTQQGHLQKHKRTHTGEKPYECNQCGKAFSEPSSLQMHKRTHNGEKLDVCN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CB33-1", "uniprot_id": "ZN735_HUMAN", "id": "P0CB33-1", "name": "Zinc finger protein 735", "aln": "---------------------------------MAKRPGPPGSREMGLLTFRDIAIEFSLAEWQCLDHAQQNLYRDVMLENYRNLFSLGMTVSKPDLIACLEQNKEPQNIKRNEMAAKH----------------PVTCSHFNQDLQPEQSIKDSLQKVIPRTYGKCGHENLQLKKCCKRVDECEVHKGG----YNDLNQCLSN-----------------------------------------------------------------------------------------------------------------------TQNKIFQTHKCVKVFSKFSNSNRHNARYTGKKHLKCKKYGKSFCMFSHLNQHQIIHTKEKSYKCEECGKSFNHSSSGTTHKRILTGEKPYRCEECGKAFRWPSNLTRHKRIHTGEKP------------------------------------------------------------------------------------YACEECGQAFRRSSTLTNHKRIHTGERPYKCEECGKAFSVSSALIYHKRIHTGEKPYTCEECGKAFNCSSTLKTHKIIHTGEKPYTCEECGRTFNCSSTVKAHKRIHTGEKPYKCEE--CDKAFKWHSSLAKHKIIHTGEKPYKCK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2A8Q4-1", "uniprot_id": "A2A8Q4_MOUSE", "id": "A2A8Q4-1", "name": "", "aln": "---------------------------------MSVFLVN---TPQGLLTFKDVAVEFSLEEWERLSFAQRSLYIDVMLENYNNLLFVENHFICAKCGKALDEDSQ-----------------------------YIVHEHMN--IQEKSSKWNKLSNVILESP------------------HCVPHK------CSEWDKCFS----------------------------------------------------------------------------------------------------------------------------------------QRSHLSIHQKIHTGEKPYKCSECDKCFTEKGILRIHQKIHSGEKSYKYHECDKCFPKKSHLSIHLRIHKGEKPYKCSDCDKCFTEKRKLRRHQKIHTGEKP------------------------------------------------------------------------------------YKCSECDKCFIQKYSLSDHQRIHTGEKPYKCSECNKCFIQKSSLNNHQSIHTGEKPYKCSECDKCFTDKRNLRRHQKIHTGEKPYKCSECEKCFTDKGSLRRHQKIHTGEKPYKCSE--CEKCYTDKGSLRRHQKIHKGEKLTNAVNVTNALLKKAI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M9PGG2-1", "uniprot_id": "M9PGG2_DROME", "id": "M9PGG2-1", "name": "", "aln": "MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNPGAIGATPAQWGSEMYPNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQPQSPPGGGQEARDNGSGDGRQQQVSPSSSPYPSVQQQQRANGAGDEDPMNHQLANQQNPAPNQNQSSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQGGMLAPPGFPPLHYLNKGVLPMEQSGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGAGANGSGGVGGATGASVGVGSVGVTSGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNTTKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQVANHLMNDAKSLAAQQFLNNNNPSAVDNKANILPVRSIASNAAAAAVVQQSVVKNELYFPQCYGPPFQHPFQAQQQQAQQPSVAHANGGPTPPVTVTVANSVASGVVVQQNASASVVAQXHPTTAATGAQQQQPSAPQQQHHPPPPPPTSTAHHIASAAAAVTAVTPSSAHASPVAAPQTVTLSITLPPPPASHTVHPGHPGHPGHPGVANGAAPPPPTLSHAIPIHPHIHSIFGSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: : :. : : .: . : * .: .: : * :*. : *.: .* * * * *: **.: *.:.* : * * .****: * :*.* * * * * . .* * *.: * * .* * . *: * :*.* * * * **.***: * * : * *. * ***:*** * :* : * : * : * *: *: * : : : : : : ", "identical_positions": 64, "similar_positions": 61, "identity": "6.82%" }, { "cls_id": "homologset.agr.HGNC:32467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M9PGG2-1", "uniprot_id": "M9PGG2_DROME", "id": "M9PGG2-1", "name": "", "aln": "MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNPGAIGATPAQWGSEMYPNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQPQSPPGGGQEARDNGSGDGRQQQVSPSSSPYPSVQQQQRANGAGDEDPMNHQLANQQNPAPNQNQSSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQGGMLAPPGFPPLHYLNKGVLPMEQSGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGAGANGSGGVGGATGASVGVGSVGVTSGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNTTKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQVANHLMNDAKSLAAQQFLNNNNPSAVDNKANILPVRSIASNAAAAAVVQQSVVKNELYFPQCYGPPFQHPFQAQQQQAQQPSVAHANGGPTPPVTVTVANSVASGVVVQQNASASVVAQXHPTTAATGAQQQQPSAPQQQHHPPPPPPTSTAHHIASAAAAVTAVTPSSAHASPVAAPQTVTLSITLPPPPASHTVHPGHPGHPGHPGVANGAAPPPPTLSHAIPIHPHIHSIFGSL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B4DX44-1", "uniprot_id": "ZN736_HUMAN", "id": "B4DX44-1", "name": "Zinc finger protein 736", "aln": "--------------MGVLTFRDVAVEFSPEE-------WECLDSAQQRLYRDVMLENYGNLVSLGLAIFKPDLMTCLEQRKEPWKVKRQEAVAKHPAGSFHFTAEILP-------DHDIKDSFQKVILR-------------KYGSCDLNNLHLKKDYQSVGNCKGQKSSYNGLHQCLSATHSKTCQCNKCG----------------------------------------------------------RGFQLCSIFTEHKDIFSRE---------------------------------------------------------KCHKCEECGKDCRLFSDFTRHKKIHTVERCYKCEECGKAFKKFSNLTEHKRVHTGEKPYKCEGCGKTFTCSSTLVKHKRNHTGDRPYKCEECGKAFKCFSDLTNHKRIHTGEKP------------------------------------------------------------------------------------YKCEECNKAYRWFSDLAKHKIIHTGDKPYTCNECGKAFKWFSALSKHKRIHTGEKPYICEECGKAFTRSSTLFNHKRIHMEERPYKCEECSKTFKCFSDLTNHKRIHTGEKPYKC--EECGKASSWFSHLIRHKRIHTREKLHKC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . *:: :: : :. *: :: .. ::*. : .: : :*. :*::: : * *. ...: .: * *:. *. *: : *: * : :: : *. : ::** : *. .* .* . : :: * ..: * .::. ::: .. : .** **** : * : :*.:*** * : *.**** *:: *:**:* *:*:.***:.* *.::* : * :* * *:*::*: * **** *: : *.:* * * . .* :* *:* :: : * :* ** .:**.* **** *: * *::* ****.***: * * : * : : * :* *** *:**** :*.* *: : * :*.* * *::*: * :* : : ..: :* * . : * ", "identical_positions": 121, "similar_positions": 139, "identity": "12.9%" }, { "cls_id": "homologset.agr.HGNC:3247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07896-1", "uniprot_id": "ECHP_RAT", "id": "P07896-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MAEYLRLPHSLAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAFTP-GLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPVEEAIKFAQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQGSPPLKEWQSLAGPHGSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBM2-1", "uniprot_id": "ECHP_MOUSE", "id": "Q9DBM2-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MAEYLRLPHSLAMIRLCNPPVNAISPTVITEVRNGLQKASLDHTVRAIVICGANDNFCAGADIHGFKSPT--GLTLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEEAIKFAQTVIGKPIEPRRILNKPVPSLPNMDSVFAEAIAKVRKQYPGRLAPETCVRSVQASVKHPYEVAIKEEAKLFMYLRGSGQARALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEAS---KSGQASAKPNLRFSSSTKELSSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEGSKPEDVDGVLEEFGFRMGPFRVSDLAGLDVGWKVRKGQGLTGPSLPPGTPTRKRGNTRYSPIADMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSEFLSQYRETHHIKQRSISKEEILERCLYSLINEAFRILEEGMAASPEHIDVIYLHGYGWPRHVGGPMYYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQGSPPLKEWQSLAGPHSSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08426-1", "uniprot_id": "ECHP_HUMAN", "id": "Q08426-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MAEYTRLHNALALIRLRNPPVNAISTTLLRDIKEGLQKAVIDHTIKAIVICGAEGKFSAGADIRGFSAPRTFGLTLGHVVDEIQRNEKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSDYLKKLASQGNPPLKEWQSLAGSPSSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYL3-1", "uniprot_id": "ECHP_DANRE", "id": "Q6NYL3-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MARYELVKRSVALITLTNPPVNALSSAVRHAISKTMERALSDPKVTAVVICGENGRFCGGADIREFAGPLR-GPPLVPLLDAIEAGEKPVVAAIEGVALGGGFELALVCHYRIAHYKARLGLPEVTLGILPAAGGTQRLPRLIGIPAALELITTGRHVSAQEALKLGMVDQVTEQNTCEVALEFALKAVGKPLSSRRLSMLTTPCPPGLDGIFEAATMQVQKKARGVMAPLACVQAVRAAT-LPYSEGIKREGELMATLFSSGQAQALQYSFFAQRTAEKWTLPSGAQWNNSKPREIQSAAVIGLGTMGRGIVVSLARVGISVIAVESEKKLLETGRQMVIGMLERDAK---RRGVSASLNLLKFSLSLQDLKDVDLVIEAVFEDMALKKQIFRELSRVCRPATLLCSNTSGLDVDALADVTDRPQLVAGMHFFSPAHVMKLLEVVCGPRSSKEAIATAMSLGKRMGKVSVAVGNCPGFVGNRMLMPYLEQATFLLEEGATPQQIDKALEDFGFAMGVFRMSDLAGLDVGWRVRKESGLTGPDVDPKDPPRRRQGRKYCPIPDMVCQQGRFGQKTGRGWYMYDKPGDTNAKPDPLIQNLLETYRSRYGIQPRKITDQEIIERCLFALANEGFRILKDKIAGQPEDIDVIYLFGYGFPRHRGGPMFYASMVGLERVLERLEYYHHALPDVPHLEPSPLLKKLVARGSPPIQKWREHIKSMHSHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* : .::*:* * ******:*.:: : : :::* * .: *:**** :..*..****: * . * .* ::* *: :***:***:*:*:***:**** ******: :*::*:*** **:**.* *** ***: *:*.**:***:*: : ::***:**::* *.:.:. * *:.** .:*:..**: . . *.:*.:* * ::::: * :* :**::::*:. **. .**.* :*: * ****:****:***::.*:**: ****.*:.:..: :.*..*:*********.:*:**. *.*:**:*: : * :..::: **::*. : * . : ::: * ::* ****:*****:* ***::* *** :*:* ::**:***.*:** :*. ****:** * *******:*:****: . ** :***.*.*.*:: *:.*.**** ******** ** :*. **:***:.*:::* .**:*** ** **:**********: ** .***** : * * *:* . :*.*: *::*: ********:*** **** . **** :. :*. **. : *: *.*:.:**:****::* **.**** : :*. **.***:**.***:*** ****:**: *** ***:*: *:: **:*:**** *::*.::*.**:::*:. . *:*", "identical_positions": 344, "similar_positions": 230, "identity": "47.58%" }, { "cls_id": "homologset.agr.HGNC:32479", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGS2-1", "uniprot_id": "BOLA2_MOUSE", "id": "Q8BGS2-1", "name": "BolA-like protein 2", "aln": "-----------------------------------MELSADYLREKLRQDLEAEHVEVEDTTLNRCATSFRVLVVSAKFEGKPLLQRHRLVNECLAEELPHIHAFEQKTLTPEQWTRQRRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEV8-1", "uniprot_id": "A0A8I6AEV8_RAT", "id": "A0A8I6AEV8-1", "name": "BolA-like protein 2", "aln": "-----------------------------------MELSADYLREKLRQDLEAEHVEVEDTTLNRCVTSFRVLVVSAKFEGKPLLQRHRLVNECLAEELPHIHAFEQKTLTPEQWTRQRQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3K6-1", "uniprot_id": "BOLA2_HUMAN", "id": "Q9H3K6-1", "name": "BolA-like protein 2", "aln": "-----------------------------------MELSAEYLREKLQRDLEAEHVEVEDTTLNRCSCSFRVLVVSAKFEGKPLLQRHRLVNACLAEELPHIHAFEQKTLTPDQWARERQK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z933-1", "uniprot_id": "A1Z933_DROME", "id": "A1Z933-1", "name": "BolA-like protein 2", "aln": "----------------------------------MSKYDSKYLEEKLKRELQTEYVSVTDES-DGCGGKFSAVIVSPAFSGKTLLQKHRLVNSTLAEELKEIHAFSQKSYTPEEWEKVKAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53082-1", "uniprot_id": "BOL2_YEAST", "id": "P53082-1", "name": "BolA-like protein 2", "aln": "MTGERIEKVKINDEFAKSHFLTTQWRETKRQRHYKMPVTEQGLRERIESAIPQVYHIIVTDLSYGCGQSFDIVVVSDFFQGKSKLMRSRAVNKAVKEELQEIHAFSCKCYTEEEWSKIVV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.*::. : : : * .* ::** *.**. * : * ** : *** .****. * * ::* : ", "identical_positions": 23, "similar_positions": 20, "identity": "19.01%" }, { "cls_id": "homologset.agr.HGNC:32480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA62-1", "uniprot_id": "D4AA62_RAT", "id": "D4AA62-1", "name": "PAK4-inhibitor INKA1", "aln": "--MHSARLDSFLSQLRWELLCARDTASPPMPGPLQPK---------PKTDQNIQPKRRFRASDVLEE---DSVCCVEEEEEE---GLVAEDRGAPLGCPREHALDWDSGFSEVSGSTWREEELSVPRRQAPPERPPHSQRFSVSDLPVRSRAAVTNIPPAHRPRPKSTPDACLEHWQGLE----AEDWTAALLNRGRSRQPLVLGDNCFADLVHNWMELPEATSEGSDGDVPRARARPPQFLLGLSEQLR--RRLARARRT----------AMAGKRLSCPPRPEP-------------DLPADISRFAALMNCRSRQPIIYNDVS-YL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX62-1", "uniprot_id": "INKA1_MOUSE", "id": "Q9CX62-1", "name": "PAK4-inhibitor INKA1", "aln": "--MHSARLDSFLSQLRWELLCARDTGSPPMSGPLQPK---------PRTDQNVQPKRQFRASDVLEE---DSVCCVEEEEEE---GLVAEDKGLPLGCPREHALDWDSGFSEVSGSTWREEEPSVPQRQAPRERPPHSQRFSVSDIPMRSRAAVTNIPPAHRPRPKSTPDACLEHWQGLE----AEDWTAALLNRGRSRQPLVLGDNCFADLVHNWMELPEATSEGSDGDVPRARARPPQFLLGLSEQLR--RRLARARRT----------AMASKRLSCPPRSEP-------------DLPADISRFAALMNCRSRQPIIYNDVS-YL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EL1-1", "uniprot_id": "INKA1_HUMAN", "id": "Q96EL1-1", "name": "PAK4-inhibitor INKA1", "aln": "MDMHSARLDSFLSQLRWELLCGRDTGSPSMPGPLQPT---------SQTGPDVQPSHQLRASGALEE---DSVCCVEEEEEEEEEAVVTEDRDAALGGPREHALDWDSGFSEVSGSTWREEELPVSQRPAPSAQPLRRQCLSVSGLPMPSRAPVASVPPVHHPRPKSTPDACLEHWQGLE----AEDWTAALLNRGRSRQPLVLGDNCFADLVHNWMELPETGSEGGDGGGHRARARPPQFLLGLSEQLR--RRLARARRT----------AMAGKRLSCPPRPEP-------------ELPADVSRFAALMSCRSRQPIICNDVS-YL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QR98-1", "uniprot_id": "INK1A_DANRE", "id": "F1QR98-1", "name": "PAK4-inhibitor inka1", "aln": "MLCLQESGDCLRDQMRYMMRSLQDLKHLRRSCVAPPVGPPVRLRACKQLIAQRERRARLRISDASEASSYDSACCLSSSLEEEE---SASDPSAVSSPSSERSLEFDSGYSEAS---WQDEGVVLRRTKNIRVSS--------------TACLRTNQLSNTRARPKSTSDACLESWTSFETASDPEDWTTSLLTRGRNRQPLVLGDNSFADLIHNWMDLPECP-EQTELKHSSGRSFAKDFLVNIKRRIAGFSRSADGRRKSSDVTKLSKSIVPTKRLSCQIDVQHKMPFFYKSHTGLNELDTDYYQFSALMKSGSRTPIVCNDIIGYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QPR4-1", "uniprot_id": "INK1B_DANRE", "id": "F1QPR4-1", "name": "PAK4-inhibitor inka2", "aln": "MLCVRNSGECFRDHMRHMMRSLQDLKQIREPDDQSKCSYVTRAR--QKRIKQREQLSRLRISDVSDTSTYDSACCLASPLEEEEDQENHAERLAQGSPSSIKSLDFDSGYSEAS---WQDEGVVLRRTRNVRVSS--------------SACVRTN-----RIRPKSTSDACLERWTSFE-ASDPTDWTTSLLTRGRNRQPLVLGDNSFADLIKNWMDLPECP-DSAELKPSR----KTAFLVNMRRKIAGISKGLEERRS-----------AEAKRMSCPVGFQPPKPFFHQSHTSLHPMGTDFYQFSSVMKSGSRQPIICNDVIGYI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: .::* : . :* . : : : ::* *.. : **.**: . ** : . . ::*::***:**.* *::* : : . : . :. : *****.***** * .:* . ***::**.***.*********.****::***:*** : : **:.: .:: : **. **:** : : :* :*:::*.. ** **: **: *:", "identical_positions": 76, "similar_positions": 75, "identity": "23.1%" }, { "cls_id": "homologset.agr.HGNC:32483", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BLS0-1", "uniprot_id": "OST4_RAT", "id": "B0BLS0-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "aln": "MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPK---KQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LX8-1", "uniprot_id": "OST4_MOUSE", "id": "Q99LX8-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "aln": "MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPK---KQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C6T2-1", "uniprot_id": "OST4_HUMAN", "id": "P0C6T2-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "aln": "MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPK---KQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H0WEU8-1", "uniprot_id": "H0WEU8_DANRE", "id": "H0WEU8-1", "name": "", "aln": "MVTDVQLAIFANMLGVSLFLLVVLYHYVAVNNPK---KLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7U3-1", "uniprot_id": "OST4_DROME", "id": "A1Z7U3-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Ost4", "aln": "MITDVQLAIFSNVLGVFLFLLVVAYHYINANTGKPSAKAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:********:*:*** ****** ***: .*. * * :", "identical_positions": 25, "similar_positions": 7, "identity": "62.5%" }, { "cls_id": "homologset.agr.HGNC:32484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K619-1", "uniprot_id": "A0A0G2K619_RAT", "id": "A0A0G2K619-1", "name": "", "aln": "-----------MEPNACKTSESEEDDIEEEESEEECVREESTTP-NSSQQALGKADYKEFENGVALSVVAKNIPKKILSTTDTDDLEVGRRK-------------------------------RKRKRRPLAINLTNCKYESVRRAAQMCGLKEVGEDEEWTVYWTDCSVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMQKLYPTEYNIFPRTWCLPADYGDFQAYGRQRKTRTYICKPDSGCQGRGIFITRTPKEIKPGEHMICQQYITKPFLIDGFKFDMRIYVLITSCDPLRIFMYEEGLARFATMPYVEPSHNNLDRTGQSGEEGQELSNLGAEQWEEVCMHLTNYAINKHNENFVRDD--AVGSKRKLSTLNAWLREHSHDPRELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLCGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSRLDREVKDALLCDAMNLINLRGCDKKKVIEEEKRRVKERLFPCHQQPREARREQ--------------LESSQAAMHD-QELYEDSHLGGYRRIYPGPDS---EKYAPFFKHNG-SLFQETAASKAREECARQQLEEIRLKQEQQENPGTKKRKENKEQNQGESAGEKSRSRVATRVLATNLAYRNRNQEKELLPVQLDTMQPQDIVEEEELERMKLLLQRENLIRSLGIVEQLTRMLYPSHRSHRKLHEYRPRFHQDGLSSQELQPVNLVPLVFLRGAASEHIPPHFLQPLRP-----HELIPRILGPLSSMNPAIAQHSRYHLQPKNFNWIGDSAATGPCSLS-VKKSGRHYFSSSRVRLTSQGQASRRLEAINRALSGS-VPPTLTPKQGYL--LQPERQENGSWTECCNLPCMVNSEHRGTKAGDLTLCPASAPVLQHSSPLLNIIQHR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4Q9F6-1", "uniprot_id": "TTL13_MOUSE", "id": "A4Q9F6-1", "name": "Tubulin polyglutamylase TTLL13", "aln": "-----------MEPNNCKTSESEEDDIEEEESEEECVREESTTP-NSTQQALRKADYKEFENGVALSVVAKKIPKKILSATDTDDLEVGRRR-------------------------------RKRKRRPLAINLTNCKYESVRRAAQMCGLKEVGEDEEWTVYWTDCSVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMQKLYPTEYNIFPRTWCLPADYGDFQAYGRQRKTRTYICKPDSGCQGRGIFITRTPKEIKPGEHMICQQYITKPFLIDGFKFDMRIYVLITSCDPLRIFMYEEGLARFATMPYVEPSHNNL---------------------EEVCMHLTNYAINKHNENFVRDD--AVGSKRKLSTLNAWLREHSHDPQELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLCGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSRLDREVKDALLCDAMNLVNLRGCDKKKVIEEDKRRVKERLFPCHQQPRETRREQ--------------FELSQAAMHD-QERYEDSHLGGYRRIYPGPDS---EKYAPFFKHNG-SLFQETAASKAREECARQQLEEIRLKQEQQENPGTKKRKENKEQNQGESAGEKSRSRTATRVLATSLAYRNRNREKELLPVQLDTTQPQDIVEEEELERMKLLLQRENLIRSLGIVEQLTRMLYPSHRSHRKLHEYRPRFHQDGLSSQELQPVNLVPLVLLRGAASEQIPPHFLQPLRP-----HELIPRILGPLSSINPAIAQHSRYHLQPKNFNWIGDSAATGPCSLS-MKKSGRHYISSSRVRLTSR---KRRKAQHSTKTANG-LQSLLIER------LPTSSRLKSSGQDLCLQKAKNTETPR---------------VLQHSKILWGSVKTKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNM8-1", "uniprot_id": "TTL13_HUMAN", "id": "A6NNM8-1", "name": "Tubulin polyglutamylase TTLL13", "aln": "-----------MEPSTCRTMESEEDYVEEKESEK-CVKEGVTNPSNSSQQALLKADYKALKNGVPSPIMATKIPKKVIAPVDTGDLEAGRRK-------------------------------RRRKRRSLAINLTNCKYESVRRAAQMCGLKEVGEDEEWTLYWTDCAVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMYKLYPSEYNIFPRTWCLPADYGDFQSYGRQRKARTYICKPDSGCQGRGIFITRNPREIKPGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLRIFTYEEGLARFATTPYMEPSHNNL---------------------DNVCMHLTNYAINKHNENFVRDG--AVGSKRKLSTLNIWLQEHSYNPGELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLNGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSCLDQEVKDALLCDAMTLVNLRGCDKRKVMEEDKRRVKERLFQCYRQPRESRKEK--------------TESSHVAMLD-QERYEDSHLGKYRRIYPGPDT---EKYARFFKHNG-SLFQETAASKAREECARQQLEEIRLKQEQQETSGTKRQK-ARDQNQGESAGEKSRPRAGLQSLSTHLAYRNRNWEKELLPGQLDTMRPQEIVEEEELERMKALLQRETLIRSLGIVEQLTRLQHPGPQGQKKLHESR-----DRLGSQELKSMSLVLLVLLRGAATEQGAPHFLHPVLP-----HESIPRILGALPSMNAAIPHVPRYHLQPKNFNWTGEPAAINSCSLS-MKKAGRCYFSSARIRLTSQGQASRRLEAINRVLAGS-VPPTLTPKQGYF--LQPERVASDSWT-ECTLPSMVNSEHR---AAKVPLCPASAPMLQRSRALLNINQFR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8CVX7-1", "uniprot_id": "TTLL6_DANRE", "id": "A8CVX7-1", "name": "Tubulin polyglutamylase ttll6", "aln": "-----------------------MGTPAERSVSEVCRCE--PDP-GLEGEGWGSDTHAEPSN--------TPIP-----------LPVANKK-------------------------------KKRKKK-LWINLTNCKYESVRRAARRYGIREAAEGEDWTLYWTDCSVSLDRVMDMKRYQKINHFPGMNEICRKDLLARNMNRMLKLFPKEYNIFPRTWCLPADYSDFQAYTRAKKHKTFICKPDSGCQGRGIYLTKSSKDIRPGEHMICQVYMSKPFIIDGFKFDLRIYVLVTSCDPFRVFMYDEGLVRFCTTHYTEPTVSNL---------------------EDVCMHLTNYAINKHSENFVRDE--DTGSKRKLSSFKKHMEDMSYDTEKLWTDIEDAIIKTLISAHPILKHNYQTCFPNHASG--SACFEILGFDVLLDRRLKPWLLEVNHSPSFTTDSRLDREVKDSLLYDTLVLINLGACDRRKITEEEKRRVKERLQ--QNRSREARNEE--------------PRQSQAASMELMQKYEAKHMGGFRRIFPRDGG---EKYEKYFQHSS-SLFQETAASKAREECARQQLQELRLKQEQKER---DKKGSRKQDLQGESAGEKVKPRKSQPPHKTSNSLP---AMLELSSVREETPVSLERIEKEEAERVRELQQRETLLLNMGVVNQVRQLLQSANRLTQCINHSHEQASFPPHCRHDHKLDTLAEISWRQKNIYSTMQHQILARNRPSLPNVHSQTLQNRKPWPSLEHGLLQPVQTQAAALKHYGLEEMVASNAEEQANLIKAT----SAQQIPLTINGSFIWRQGSLSSSLAESRARATMLAMPP----LGPGRLHRPTIFHDPNSLSIISTPAP-----LVPRPHLSHDLRKAPRRVLPHEHSL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBN5-1", "uniprot_id": "A1ZBN5_DROME", "id": "A1ZBN5-1", "name": "", "aln": "MPSKKSPRPTYCEPNPYTRFFNAHKSLPPDKNGQKQEIYNRESVYVLSNKSRGKRRSGRENNQPTWRRRGGGVNEDHIMVVTQDNTQQQRDKPLLTASQLDSICYDVIKEPPMQFHVNGTDIVPSIRGLRLSVCVEHTRFQLVAKVTRNMGFQHVPEHRLWNIQWSDSTPHHDLLRNMKRFQQINHFPGMVEICRKDLLSRNLNRMLKMFPGDYRIFPKTWLMPTDAYDVAIYAN-KHKRTFILKPYSAGQGRGIWITTDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTTGNS---------------------HNVFMHLTNYCLNRRNSQYMVGNGPEAGSKRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTLISAWPTLKHNYNVCFP--KHDKIQASFQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDTLNMLSTALVDKEQIIRDDRTEHRARLLRNIYNKKAAAQMPGYSSPIREVGGHDVRQACSIGALTQQIAWEESHLGNYRRIMPPRDSSKVNYYCKFYEQNKQPMFADTVASRRREQLNLQAIQKHQRER-QQDLIQQQQIHTQAQNRMGKHVRWPGDLVQGEQVNPVILQSRRRREEAEAYAKKHRALIAREIQR-----------QKEQLLAPTCAKERLGIWQSVRREKRSQFSPKRGSSITKAYRRKQQRNLSLRARQQRMIEMEAQRDAKFLEQHAQ-----KQRLEGGRKTGQSESPNLLSKITAKSKTSLKKKMKPKGKPELKKET-LQEGNHCQMTKSKVELTPGSKARAFANWTARTINEAETDQLLSWRKERANQLNETRLRELIFSKMYENGHLTKNDIK----------CFPDLLYQILNNDCKEASSR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. . .* : . : : * : : : ::: * :.:: *::.. * . *.: *:*.: : : :***:*:******* ********:**:*** *::* :*.***:** :*:* *. * . :: :*:* ** *. *****::* : : *::*** *: :*::***:***:*:*.*:** **:*:* *:***.**.* * *: .* .:* ******.:*::..::: . .*******::: : : .:: ::* .::* ****:*** . *:***..*** . *.*::****:*:* :***::*****:**:::*. :* *** .*: *:: ::. *:.:: .::: . : ** . : : . . . . :* .*:* :*** * . : * ::::. .:* :*.**: **: * ::: : :: *:: .: :: *: . . . * . : : . : . *:* *: ::: . : : :: : .* ::* :. . * . : : . . : : :. : :: ** . : * . : : ", "identical_positions": 172, "similar_positions": 216, "identity": "18.7%" }, { "cls_id": "homologset.agr.HGNC:32486", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCW1-1", "uniprot_id": "D3ZCW1_RAT", "id": "D3ZCW1-1", "name": "", "aln": "MSTSLTTCEWKKVFYEKMEVAKPADSWELIIDPNLKPNELGPGWKQYLEQHASGRFHCSWCWHTWQSANVVILFHMHLDRAQRVGSVRMRVFKQLCYQCGTSRLDESSMLEENIEGLVDNLITSLREQCYDEDGGQ-YRIHVASRPDTGLHRSEFCEACQEGIVHWKPSEKLLEEDAA-FT-DDSKRKGQAGFISDFFSFRWCLFWGALCLVIVYLQFFRGRSGFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZI2-1", "uniprot_id": "RTP2_MOUSE", "id": "Q80ZI2-1", "name": "Receptor-transporting protein 2", "aln": "MSTSLTTCEWKKVFYEKMEVAKPADSWELIIDPTLKPNELGPGWKQYLEQHASGRFHCSWCWHTWQSANVVILFHMHLDRAQRVGSVRMRVFKQLCYQCGTSRLDESSMLEENIEGLVDNLITSLREQCYDEDGGQ-YRIHVASRPDSGLHRSEFCEACQEGIVHWKPSEKLLEEDAA-YT-DASKKKGQAGFISSFFSFRWCLFWGTLCLVIVYLQFFRGRSGFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QGT7-1", "uniprot_id": "RTP2_HUMAN", "id": "Q5QGT7-1", "name": "Receptor-transporting protein 2", "aln": "MCTSLTTCEWKKVFYEKMEVAKPADSWELIIDPNLKPSELAPGWKQYLEQHASGRFHCSWCWHTWQSAHVVILFHMFLDRAQRAGSVRMRVFKQLCYECGTARLDESSMLEENIEGLVDNLITSLREQCYEEDGGQ-YRIHVASRPDSGPHRAEFCEACQEGIVHWKPSEKLLEEEVTTYTSEASKPRAQAGSGYNFLSLRWCLFWASLCLLVVYLQFSFLSPAFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A889-1", "uniprot_id": "A0AB13A889_DANRE", "id": "A0AB13A889-1", "name": "", "aln": "----MASMLWESSLREKSSDLH-EDTWHITIDDSIEPHRQARDWYQYISG-SFARFRCSLCKRGWVSKRVQVVFHFNLNAAKREGTIKLRRFKQKCRRCNEARMEDPNFAVENIDVLIERLVEKIRMRCYSENLGENNRPSVFSGRVNGPHESQHCEACQSGICSQAN----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: *:. : ** . : *:*.: ** .::* . . .* **:. : .**:** * : * * .* ::**: *: *:* *::::* *** * .*. :*:::..: ***: *::.*: .:* :**.*: *: * * * .* *.::.*****.** ", "identical_positions": 54, "similar_positions": 59, "identity": "23.89%" }, { "cls_id": "homologset.agr.HGNC:32487", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6J4-1", "uniprot_id": "ALKB2_MOUSE", "id": "Q6P6J4-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "------------------------------------------------MDKFLVRPDLRDLQGGGEEPAPTGGASGDLKSPDWRHLRAEGLSCDYTVLFGKAEADKIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLTPKPWVPVLERVRDRVCEVTGQTFNFVLVNRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFIFRHKDSRGKRPRRTVEVVRLQLAHGSLLMMNPPTNTHWYHSLPIRKRVLAPRVNLTFRKILPTKK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5G5-1", "uniprot_id": "A0A0G2K5G5_RAT", "id": "A0A0G2K5G5-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "MCRALARVAAPDPPVEHGCVPVLAYPAGRRTEAPCFSGTRLWLAGGGGMDRFLVRPDRGDIQGAAEEPAPTGEASGDMQSPGWQHFRAEGLNCDYTVLFRKAEADQIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLTPKPWIPVLERVRDQVCRVTGQTFNFVLVNRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDILFRHKDSRGKRPRRAVEVVRLQLAHGSLLMMNHPTNTHWYHSLPIRKRVLAPRINLTFRKILPTKK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NS38-1", "uniprot_id": "ALKB2_HUMAN", "id": "Q6NS38-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "MDRFLVKGAQGGLLRKQ------------EEQEP------------TGEEPAVLGGDKESTRKRPRREAP--GNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTKK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3QK41-1", "uniprot_id": "A3QK41_DANRE", "id": "A3QK41-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "MDKFLTRKRKR-----------------------------------SSEEPDEWKTEALIKKPTEEEECEEGEEEFSNPIP-WQKIEAEGLDCDYSLLFNKEEADHLFNQLEEEVEYFTGDNAKLQVYGKSYNIPRKQATYGDEGLMYSFSGVNLLAKPWTSTLEHIRDAVTKATGYTFNFVLINRYKDGHDHIGEHRDDERELDPACPIASVSLGAARHLIFRHRDARTGPRKRQIEPVKLELANGSLLLMNFPTNTYWYHSLPIRKKVITPRINLTFRRIVKNRQKNGTKTE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .. . * *:::.****.*.*::** * ***.:*.:**:******* *::**:** :.:********* ** *:***:.* .*** ..**::** * .** ******:****** ************* *..******:**.*.::***:*:* * : *:* **:****:** ****:******:**:*::**:*****:*: .:: ", "identical_positions": 127, "similar_positions": 59, "identity": "43.2%" }, { "cls_id": "homologset.agr.HGNC:32488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1RIV1-1", "uniprot_id": "A0A8M1RIV1_DANRE", "id": "A0A8M1RIV1-1", "name": "", "aln": "MKMMDSRSLRSVSALLLFLQFCWCFSDGDQKSRPNFVLMMVDDLGIGDIGCYGNTTIRTPNIDRLASDGVKLTHHLSAAPLCTPSRTAFMTGRYPLRAGMGSTG-RVQVILFLAGSGGLPPNETTFAKLLQKQGYTTGIVGKWHLGVNCESRSDLCHHPNNHGFDFFYGLPFTLFVDCAVGAGSGVLLDYQEMLLNSCKLLLVCVLTLLALRGSGLLCAGWRLLFHLSAAALICFLLWFVPFGLLRVWNCILMRNGEVVEQPMNLQTLNSRLMREAEQFMERHRDGPFLLFVSFPQVHTPMLVTEGFAGKSRHGLYGDNVEEVDWMVGRVVDTIDRLGLTEKTLLYFTSDHGGGIE----EGPRGGWNGIYRGGKAMGGWDGGIRVPGIFRWPGRLAAGREVAEPTSLMDVFPTVVKLAGGELPKDRLLDGHDLMPLLEGSSSRSQHEFMFHYCGMYLNAVRWHPQNSSSIYKVVFFSPVFSPAGSSGCFSTGSCMCHKPHVTYHSPPLVFLISSDPSESVPLTEQTDPRVPEVLQRVQRAVEEHRRSLTPVEMQLTWRKTLWRPWLQPCCGTFPYCTCSEEDTHTTG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5FYA8-1", "uniprot_id": "ARSH_HUMAN", "id": "Q5FYA8-1", "name": "Arylsulfatase H", "aln": "---------------------------MTRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFLLLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEKVASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSG-DVTYHDPPLLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWLQPCCGTFPFCGCDKEDDILPMAP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::***:**:*.****:**: ****.:: *********:**:**:**:**.:*****:**:*****:*:** *: :.: :*.******.**********::** **::******:.* **.* *:** ****.:***:** *: ** .. . : : * * * : : ** : : :.. *:::* :: *:: * *: .:*: * ******** *:::***: :.: * :::** *:**:: *****.** :****:: .: *.*:*::* *******:*****:::*::*: *:::**:*****:** :* *******:***.****:************. * *** : *******::**: :.** *.:**::**::******* :*:*:***:*****:**::**** ::.::::*. :.:* * * *:..*:.:* * * .****.***:* ** ****::**. :.:* . .*::::: *:.****:**** *:: :*:*:***********:* *.:** . ", "identical_positions": 288, "similar_positions": 167, "identity": "48.81%" }, { "cls_id": "homologset.agr.HGNC:3249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48024-1", "uniprot_id": "EIF1_MOUSE", "id": "P48024-1", "name": "Eukaryotic translation initiation factor 1", "aln": "-------------------------------------------------------------------------------MSAIQNLHSFDPFADASKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLI-EIGLAKDDQLKVHGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41567-1", "uniprot_id": "EIF1_HUMAN", "id": "P41567-1", "name": "Eukaryotic translation initiation factor 1", "aln": "-------------------------------------------------------------------------------MSAIQNLHSFDPFADASKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLV-EIGLAKDDQLKVHGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0KVZ2-1", "uniprot_id": "A0ABK0KVZ2_RAT", "id": "A0ABK0KVZ2-1", "name": "", "aln": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLI-EIGLAKDDQLKVHGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VZS3-1", "uniprot_id": "ETIF1_DROME", "id": "Q9VZS3-1", "name": "Eukaryotic translation initiation factor eIF1", "aln": "--------------------------------------------------------------------------------MSIQNLNTRDPFADAIKGNDDDIQDG---LVHIRIQQRNGRKTLTTVQGLSAEYDLKKIVRSCKKEFACNGTVIEHPEYGEVLQLQGDQRENICQWLT-KVGLAKPDQLKVHGF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32911-1", "uniprot_id": "SUI1_YEAST", "id": "P32911-1", "name": "Eukaryotic translation initiation factor eIF-1", "aln": "--------------------------------------------------------------------------------MSIENLKSFDPFAD--TGDDETATSN---YIHIRIQQRNGRKTLTTVQGVPEEYDLKRILKVLKKDFACNGNIVKDPEMGEIIQLQGDQRAKVCEFMISQLGLQKKN-IKIHGF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ***** .* *: . :******************:. :** *:::: **.*****.:::.** **::******* ::*::: ::** * : :*:***", "identical_positions": 55, "similar_positions": 30, "identity": "28.35%" }, { "cls_id": "homologset.agr.HGNC:325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3K7-1", "uniprot_id": "PLCB_MOUSE", "id": "Q8K3K7-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta", "aln": "-MDPWPWLTAALLLLLLLVQLSRTARFYAKVGLYCVLCLSFSAAASIVCLLRHGGR--TVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILP--KRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIPQENSAIKEPGVLPAQ------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AC45-1", "uniprot_id": "D4AC45_RAT", "id": "D4AC45-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "-------MGAAG-------RLNRTARFYVKVGLYCVLCLSFSAAASIVCLLRHGGR--TVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILP--KRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMVKENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIRVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISEIPQENSTIKESGVLPAQ------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15120-1", "uniprot_id": "PLCB_HUMAN", "id": "O15120-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta", "aln": "-MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGR--TVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP--ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTI0-1", "uniprot_id": "Q7KTI0_DROME", "id": "Q7KTI0-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "---MACTCEVIGLACVVALILSATAKAPYQMRMFFIFFGAGLIVFLCVPFMILRPR--DYRNALFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTR--NSKDSLLPFKKGSFHIALQGKSPVQPVVISKYS-FMDDEKKTFRPGHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKEGQALSSKKQA------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYJ4-1", "uniprot_id": "Q9VYJ4_DROME", "id": "Q9VYJ4-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "MITMTSFIELLGLFLLLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVSTLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAWLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTR--RNTGALHPFKKGAFHMAIDQQIPILPVVFSSYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYKPIKKVGIPAASSASTSSTTTTTLASPGTAVTPVADAAVAAAAAVASSSSAYGQPPGYEAGAAKASLLKTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33333-1", "uniprot_id": "PLSC_YEAST", "id": "P33333-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "------------------MSVIGRFLYYLRSVLVVLALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAKK-PYIMIANHQSTLDIFMLGRIFP--PGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVNTHNEGSSVKKMH---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : : . . *: :: . ..: ::: **** :*: : : .. :*:.: : .* * * :::* : : : . : ... : ::***** . : *****:*::* : : *: *** *. . : . : : * : * :.*. . .: : : * . ", "identical_positions": 32, "similar_positions": 68, "identity": "9.28%" }, { "cls_id": "homologset.agr.HGNC:3250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMJ3-1", "uniprot_id": "IF1AX_MOUSE", "id": "Q8BMJ3-1", "name": "Eukaryotic translation initiation factor 1A, X-chromosomal", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG--DDDEDIDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VV72-1", "uniprot_id": "IF1A_RAT", "id": "Q6VV72-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG--DDDEDIDDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47813-1", "uniprot_id": "IF1AX_HUMAN", "id": "P47813-1", "name": "Eukaryotic translation initiation factor 1A, X-chromosomal", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG--DDDEDIDDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7EZM1-1", "uniprot_id": "F7EZM1_RAT", "id": "F7EZM1-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG--DDDEDIDDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VEA1-1", "uniprot_id": "Q9VEA1_DROME", "id": "Q9VEA1-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENEFEKRELIFKEDQQEYAQVTKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINQGDIILVGLRDYQDSKADVILKYTPDEARNLKTYGEFPESVRINETVTFVEDGFDED-IEFG----DEISSEDDADSVDNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38912-1", "uniprot_id": "IF1A_YEAST", "id": "P38912-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MGKKNTKGGKKGRRGKNDSDGPKRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELPENAKINETDNFGFESDEDVNFEFGNADEDDEEGEDEELDIDDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:: ****: *****:.: ****::**: *****: *******:** **** :*:.***********:. .****:.***:**.:.**: **. ****.** **:** .:**** .* . :: ::* *: *: .:*:*", "identical_positions": 80, "similar_positions": 40, "identity": "52.29%" }, { "cls_id": "homologset.agr.HGNC:3252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "J3QMW5-1", "uniprot_id": "J3QMW5_MOUSE", "id": "J3QMW5-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGA-GDDDE-IMF-----DDIG-EDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QPI8-1", "uniprot_id": "J3QPI8_MOUSE", "id": "J3QPI8-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGA-GDDDQ-IVF-----DDIG-EDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VLT7-1", "uniprot_id": "A0A1Y7VLT7_MOUSE", "id": "A0A1Y7VLT7-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGP-GDDDE-IVF-----DDIG-EDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QQ02-1", "uniprot_id": "J3QQ02_MOUSE", "id": "J3QQ02-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGP-GDDDE-IVF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNG9-1", "uniprot_id": "A0A1Y7VNG9_MOUSE", "id": "A0A1Y7VNG9-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGP-GDDDE-IVF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VK80-1", "uniprot_id": "A0A1Y7VK80_MOUSE", "id": "A0A1Y7VK80-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARNLKAYGELPEHAKINETDTFGP-GDDDE-IVF-----DDIG-DEDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJE9-1", "uniprot_id": "A0A1Y7VJE9_MOUSE", "id": "A0A1Y7VJE9-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPEEARNLKAYGELPEHAKINEMDTFGP-GDDDE-IVF-----DDIG-DEDED-TDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QP87-1", "uniprot_id": "J3QP87_MOUSE", "id": "J3QP87-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGA-GDDDE-IVF-----DDIG-DEDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QNT6-1", "uniprot_id": "J3QNT6_MOUSE", "id": "J3QNT6-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGA-ADDDE-IVF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6YNI8-1", "uniprot_id": "F6YNI8_MOUSE", "id": "F6YNI8-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGP-GDDDE-IVF-----DDTG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BMJ3-1", "uniprot_id": "IF1AX_MOUSE", "id": "Q8BMJ3-1", "name": "Eukaryotic translation initiation factor 1A, X-chromosomal", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14602-1", "uniprot_id": "IF1AY_HUMAN", "id": "O14602-1", "name": "Eukaryotic translation initiation factor 1A, Y-chromosomal", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60872-1", "uniprot_id": "IF1A_MOUSE", "id": "Q60872-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VV72-1", "uniprot_id": "IF1A_RAT", "id": "Q6VV72-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VEA1-1", "uniprot_id": "Q9VEA1_DROME", "id": "Q9VEA1-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENEFEKRELIFKEDQQEYAQVTKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINQGDIILVGLRDYQDSKADVILKYTPDEARNLKTYGEFPESVRINETVTFVEDGFDED-IEFG----DEISSEDDADSVDNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38912-1", "uniprot_id": "IF1A_YEAST", "id": "P38912-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MGKKNTKGGKKGRRGKNDSDGPKRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELPENAKINETDNFGFESDEDVNFEFGNADEDDEEGEDEELDIDDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:: ****: ****:.: ****::** *****: **** :*: **** :*:.:***** ****:. .****:.*:*:**.:.*:: **. :***.** **: * .:*** .* . :: : * *: ::: *:*", "identical_positions": 67, "similar_positions": 43, "identity": "43.79%" }, { "cls_id": "homologset.agr.HGNC:32521", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A2R8QMU9-1", "uniprot_id": "A0A2R8QMU9_DANRE", "id": "A0A2R8QMU9-1", "name": "", "aln": "----MALLVLLILSLPACASMRTNREDFEGFRVEEKPEAAAFKPKQPPHIIFILTDDQGFNDIGYHSG-EIRSPTLDKLASEGVRLENYYVQPLCTPSRSQLITGRYQIHTGLQHSIIRPRQPNCLPLDVVTLPQRLQEIGYSTHMVGKWHLGFYRKDCLPTRRGFHTYFGSLTGSVDYYTYGS--CDGKSLCGFDLHEGESVAWGRAGKYSTHLYTQRVRKILATHDPTSQ--PLFIFLSLQAVHT-----PLKPPKEYIYPYRNIGNVPRRKYAAMVSIVDEAVRNITYALRKYGFYRNSVVIFSTDNG----AQPLTGGSNWPLRGCKGTYWEGGIRGVGFVHSPLIRHRRRISRDLIHITDWYPTLVGLAGGNVSQHQGLDGFDVWPTISEGKESP--RLEILHNIDPLNR---------------RSR-GSLKDGYGLWDTTVQAAIRVGDWKLLTGDPGNGDWVPPHVLTHFPSSWWHLERDIG-------------------EKRKSVWLFNVTGDPCERHDLAVHRP--DVVRELLARLAFHNRTAIPVRYPP-DDTRANPSANGGAWRPWVGEDDEEENWDGVYYKRG---KNRKRKKCRLCKLQSFFKKFNLKIMSKQI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F4Z7-1", "uniprot_id": "E7F4Z7_DANRE", "id": "E7F4Z7-1", "name": "", "aln": "----MAVRALLALSVLAYLGAADLTQDWTGPNQVEQPNHAR------PHIIFIMTDDQGFNDIGYHNT-DIHTPTLDRLAAAGVKLENYYIQPICTPSRSQFITGRYQIHTGLQHSIIRSRQPSCLPFGLRTLPQRLQEAGYATHMVGKWHLGFYKRDCLPTRRGFNTYFGSLTGSVDYYTYKS--CDGPKVCGFDLHDGERVAWGQGGRYSTHLYTQRVRKILAAHDPSSQ--PLFIFLSFQAVHT-----PLQSPKEYVYPYRRMGNMFRRKYAGMVSAVDEAVRNVTYALRKYGYYKNTVIFFSTDNG----GQPLFGGSNWPLRGRKGTYWEGGVRGIGFVHSPLLRRRRRVSRALIHITDWYPTLMRLAGGNVSQAEGLDGFDMWDTISDGKESP--RFEILHNIDPLYN---------------AARHGSLKNGYGIWNTAVQAAVRVGDWKLLTGNPGYGDWIPPQMLGNFPESWWSLERHT--------------------EAKKSLWLFNVADDPYERFDLAERRP--DVVKQLLARLSFYNRTAVPVRYPS-EDPRADPSRNGGAWGPWEGDG---ENWEPFYIKK----KKAKKQKRKFCKMKSFFRRLNIRIMSNRI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32KJ8-1", "uniprot_id": "ARSI_RAT", "id": "Q32KJ8-1", "name": "Arylsulfatase I", "aln": "-MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAEDQPSAAPPQPPHIIFILTDDQGYHDVGYHGS-DIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDN--CDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHSP-QK--PLFLYVAFQAVHT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNG----GQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASP--RTEILHNIDPLYN---------------HARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLERMA--------------------SIRQAVWLFNISADPYEREDLADQRP--DVVRTLLARLADYNRTAIPVRYPA-ANPRAHPDFNGGAWGPWASDEDEEEEDEEEEGRARSFPRGRRKKKCKICKLRSFFRKLNTRLMSHRI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32KI9-1", "uniprot_id": "ARSI_MOUSE", "id": "Q32KI9-1", "name": "Arylsulfatase I", "aln": "-MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAGDQPSVAPPQPPHIIFILTDDQGYHDVGYHGS-DIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDN--CDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHNP-QN--PLFLYVAFQAVHT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNG----GQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASP--RTEILHNIDPLYN---------------HARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLERMA--------------------SIRQAVWLFNISADPYEREDLAGQRP--DVVRTLLARLADYNRTAIPVRYPA-ANPRAHPDFNGGAWGPWASEEEEEEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSHRI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FYB1-1", "uniprot_id": "ARSI_HUMAN", "id": "Q5FYB1-1", "name": "Arylsulfatase I", "aln": "-MHTLTGFSLVSLLSFGYLSWDWAKPSFVADGPGEAGEQPSAAPPQPPHIIFILTDDQGYHDVGYHGS-DIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDN--CDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSP-QR--PLFLYVAFQAVHT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNG----GQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASP--RTEILHNIDPLYN---------------HAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLERMA--------------------SVRQAVWLFNISADPYEREDLAGQRP--DVVRTLLARLAEYNRTAIPVRYPA-ENPRAHPDFNGGAWGPWASDEEEEEE----EGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSQRI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QK47-1", "uniprot_id": "A0A8M9QK47_DANRE", "id": "A0A8M9QK47-1", "name": "", "aln": "----MDVLGLGFCLLLGLIHTIEGKVVKRGRVP--------------PHIVFVMVDDQGYNDIGYHGS-EIQTPVLDQLAGEGVKLENYYVQPICSPSRSQLMTGRYQIHTGLQHSIIRARQPLCLPPDTPTLPERLQEAGYSTHMVGKWHLGFCRPECLPTSRGFQSFLGSLTGSGDHFSFQS--CDGTEACGFDLHDGDRPAWELRGNYSTRLYTERVKDILRRHDH-RK--PLFLYVALQAVHT-----PLQAPGHLLRRYQALGNRPRRHYAAMVSGVDESVGEIVSELRERGYYDNSVLIYSSDNG----GQPLSGGCNWPLRGGKGSYWEGGVRAVGFVHSPLLKRKGVVSHALIHISDWYPTLLSLAGYRESDSNHLDGQDVWETISSDLPCP--RTEILFNIDPVSRRHGD----------INPKLLTLN-GFGIWDTGVRAAIRAGDWKLLTGNIGDGDWFPPQTMPGGPQQWQGMEKRRD-------------------QRGKSVWLFNITADPYERADLAEARP--EVVKVLLTRLSEYNRTAVSPRNPP-DDPMADPQLHGGVWTPWLGQEEHRDEGGVEEPDSIN-RKARSKSTCRLCKLRALFKKVGSRMQRATLFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVM1-1", "uniprot_id": "Q9VVM1_DROME", "id": "Q9VVM1-1", "name": "Sulfatase N-terminal domain-containing protein", "aln": "MSTHLDKFSSATSLLTGFVLCIALSNGIVATSDK-------------PNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVAPMCTPSRAALLTGKYPINTGMQHYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGYN-GHDFRDSLKSTHDHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYES--VEREIVHVIDEDVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWLQLQQVSFG---ERNISELRDQSRIECP-----DPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKP-GDPNCDPRFYHNEWTWWQDEKAS---------------SSGTIGVMKVFTLLVVFIFTSSCIN------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQS4-1", "uniprot_id": "Q8IQS4_DROME", "id": "Q8IQS4-1", "name": "Sulfatase N-terminal domain-containing protein", "aln": "-------MRGLSAFLLLLCLQRVKSD-ESAAARR-------------PNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAPAMCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPEYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELECRDRGVYVTDLLTAEAERLIKDHADKE--QPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNRRKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWRLSAL--QMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATSRALSRYDLRRLTQQRISLTRRLAAVRCG-----DLQR---SCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQELRASASRPGNRA-SMPEADPTLHTCAWESFEVLKP------------------------RIVPLECDYVGVPC---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVM4-1", "uniprot_id": "Q9VVM4_DROME", "id": "Q9VVM4-1", "name": "Sulfatase N-terminal domain-containing protein", "aln": "-------MTSGKILVLLVVSSILSLAYGSGYSTK-------------PNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPNLCTPSRATLLTGKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHDKSK---PLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEP--KPRTMIHVLDEVFGYSSY--MRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLT---KDRIRQMRSEATETCPPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLAQMYP--LQLQQLADELEQIRKTAIPSARVPHSDSRANPTFHNGNWEWWNNTDTQ---------------SGSGTFSINLWLAMGSIIGLVYRNLL-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:*:::: ** * .*:.::. :: :* :* ** * *:. * :*:***. :::*:* *:** ** :* :* *. :.: ::: ** * ::******: : : ** ***. .:* . *:: * *:: . * * * : . : * ***: : * *: *::.* . : : : : :* **.*:: :*::* * *:::: :*** . ..*:* ** * : ***.:* . : *. :. . :: * *** *. *** ::* :. . ::. :* . : . . : : :::: ** *: :* . * .: * . . ..* * : .. ", "identical_positions": 95, "similar_positions": 122, "identity": "15.06%" }, { "cls_id": "homologset.agr.HGNC:32522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q09014-1", "uniprot_id": "NCF1_MOUSE", "id": "Q09014-1", "name": "Neutrophil cytosol factor 1", "aln": "MGDTFIRHIALLGFEKRFIPSQHYV-YMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEIHTENRVIPHLPAPRWFDGQRAAESRQGTLTEYFNGLMGLPVKISRCPHLLDFFKVRPDDLKLPTDSQAKKPETYLVPKDGKNNVADITGPIILQTYRAIADYEKSSGTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYAAVEEDEMSLSEGEAIEVIHKLLDGWWVVRKGDITGYFPSMYLQKAGEEITQAQRQIRGRGAPPRRSTIRNAQSIHQRSRKRLSQDTYRRNSVRFLQQRRRPGRPGPLSTDG-TKDNPSTPRVKPQPAVPPRPSSDLILHRCTESTKRKLTSAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M707-1", "uniprot_id": "NCF1_RAT", "id": "F1M707-1", "name": "Neutrophil cytosolic factor 1", "aln": "MGDTFIRHIALLGFEKRFVPSQHYV-YMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEIHTENRVIPHLPAPRWYDGQRAAESRQGTLTEYFNSLMGLPMKISRCPHLLNFFKVRPDDLKLPNDSQVKKPETYLTAKDGKNNVADITGPIILQTYRAIADYEKGSKTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYAAVEEDEVSLSEGEAIEVIHKLLDGWWVVRKGDITGYFPSMYLQKAGEEITQAQRQIRSRGAPPRRSTIRNAQSIHQRSRKRLSQDTYRRNSVRFLQQRRRPARPGPQSPD--SKDNPSTPRAKPQPAVPPRPSSDLILHRCTESTKRKLTSAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NI72-1", "uniprot_id": "NCF1B_HUMAN", "id": "A6NI72-1", "name": "Putative neutrophil cytosol factor 1B", "aln": "MGDTFIRHIALLGFEKRFVPSQHYVRYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENHQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIK-RGAPPRRSSIRNVHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************:****** *****************:********* ********** *:.***:*******:*:*******.:******* . **.** *********:************.*.*.******* .****...:***************:*** * :**:::*****:***************:****:***:*********:***:*********:****:*** **:** ****:************:**.*:***********:*::::******: ********:***.:*************:************** .**** *.. ::: .* * ***********:****:**:*******:***", "identical_positions": 313, "similar_positions": 59, "identity": "79.85%" }, { "cls_id": "homologset.agr.HGNC:32523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q09014-1", "uniprot_id": "NCF1_MOUSE", "id": "Q09014-1", "name": "Neutrophil cytosol factor 1", "aln": "MGDTFIRHIALLGFEKRFIPSQHYVYMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEIHTENRVIPHLPAPRWFDGQRAAESRQGTLTEYFNGLMGLPVKISRCPHLLDFFKVRPDDLKLPTDSQAKKPETYLVPKDGKNNVADITGPIILQTYRAIADYEKSSGTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYAAVEEDEMSLSEGEAIEVIHKLLDGWWVVRKGDITGYFPSMYLQKAGEEITQAQRQIRGRGAPPRRSTIRNAQSIHQRSRKRLSQDTYRRNSVRFLQQRRRPGRPGPLSTDG-TKDNPSTPRVKPQPAVPPRPSSDLILHRCTESTKRKLTSAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M707-1", "uniprot_id": "NCF1_RAT", "id": "F1M707-1", "name": "Neutrophil cytosolic factor 1", "aln": "MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEIHTENRVIPHLPAPRWYDGQRAAESRQGTLTEYFNSLMGLPMKISRCPHLLNFFKVRPDDLKLPNDSQVKKPETYLTAKDGKNNVADITGPIILQTYRAIADYEKGSKTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYAAVEEDEVSLSEGEAIEVIHKLLDGWWVVRKGDITGYFPSMYLQKAGEEITQAQRQIRSRGAPPRRSTIRNAQSIHQRSRKRLSQDTYRRNSVRFLQQRRRPARPGPQSPD--SKDNPSTPRAKPQPAVPPRPSSDLILHRCTESTKRKLTSAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MVU1-1", "uniprot_id": "NCF1C_HUMAN", "id": "A8MVU1-1", "name": "Putative neutrophil cytosol factor 1C", "aln": "------------------------MYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENHQGTLTEYCSTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIK-RGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*****************:********* ********** *:.***:*******:*:*******.:******* . **.** *********:************.*.*.******* .****...:******************* * :**:::*****:***************:****:***:*********:***:*********:****:*** **:** ****:************:**.*:***********:*::::******: ********:****:*************:************** .**** *.. ::: .* * ***********:****:**:*******:***", "identical_positions": 291, "similar_positions": 57, "identity": "74.42%" }, { "cls_id": "homologset.agr.HGNC:32525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT24-1", "uniprot_id": "A0A0G2JT24_RAT", "id": "A0A0G2JT24-1", "name": "", "aln": "MNPE----------SGPGHGARTPP----MFQATRGLKANLK--------DAVARPWRSLARMP-KPE-VQDLEAAAAG----HEGLLPIERSFQNAAKSNNLDLMEKLFEKKVNINAVNNMNRTALHFAVGRNNLSAVDFLLSHKARVDVADKHGLTVLHLAAWSGSFEIMLMLVKAGADQRAKSQEGMNALHLAAQNNNLHIVDYLIQDLHLQDLNQPNERGRKPFLLAAEKGHVEMIEKLV--FLNLHTSEKDKEGNTALHLAAMHGHSPVVQVLLTQWSEVNETNELNISALQTAT------------------------RN---------GHTSLVNFLLSENADSQQQKETKEPPLHLAVINNRPAVVDSLLSAQHDVDALDQRQQTPLHVAADLGNVELVETLLKAGCNLKITDKQGKTALAVAARSHHSLIVDMLIKAERYYAWRE----EHPENIQDSAVSSTLTFKQDHSLETRHVRMLLWNLAYRQLKRKDWQRLARLWSFTEDQIRAIEEQWSGNDSFHEHGYRALLIWLHGALMTQSDPAKQLYEELVRAGFPELAEKSRRFKSKTDSSSKKCAVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14DN9-1", "uniprot_id": "AKD1B_MOUSE", "id": "Q14DN9-1", "name": "Ankyrin repeat and death domain-containing protein 1B", "aln": "MNPE----------SAQGHGARAP-----MLQAARGLKANLR--------DVATRPWRSLARMP-KPE-VQDPETAAAG----HEGLLAIERSFQNAAKSSNLDLMEKLFEKKVNINAVNNMNRTALHFAVGRNSLSAVDFLLSHKARVDVADKHGLTVIHLAAWSGSFEIMLMLVKAGADQRAKNQEGMNALHLAAQNNNLHIVDYLIHDLHLHDLNQPNERGRKPFHLAAERGHVEMIEKLI--FLNLHTSEKDKDGNTALHLAAMHGHSPAVQVLLTQWSEVNESNELNVSALQTAT------------------------RN---------GHTALVNFLLGENADLQQQKESKEPPLHLAVINNRPAVVNSLLSARHDVDVLDQRRQTPLHVAADLGNVELVETLLKAGCNLKITDKQGKTALAVAARSQHSLVVDMLIKAERYYAWRE----EHRESIQDSAVSSTLTFKQDHSLETRQIRTLLWNLAYRQLKKKDWQRLARLWSFTEDQIRAIEEQWSGNDSFHEHGYRALLIWLHGALLTQLDPAKQLYEELLCAGFPELAEKIRQFKSKTDSSSKKCAVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHY2-1", "uniprot_id": "AKD1B_HUMAN", "id": "A6NHY2-1", "name": "Ankyrin repeat and death domain-containing protein 1B", "aln": "MDPAG---------RARGQGATAGGLLLRAAAAAKGLREDLW--------GAAALPWRSLSRIP-KREGLGEEDTAVAG----HELLLPNERSFQNAAKSNNLDLMEKLFEKKVNINVVNNMNRTALHFAVGRNHLSAVDFLLKHKARVDVADKHGLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYLIQDLHLKDLNQPDEKGRKPFLLAAERGHVEMIEKLT--FLNLHTSEKDKGGNTALHLAAKHGHSPAVQVLLAQWQDINEMNELNISSLQIAT------------------------RN---------GHASLVNFLLSENVDLHQKVEPKESPLHLVVINNHITVVNSLLSAQHDIDILNQKQQTPLHVAADRGNVELVETLLKAGCDLKAVDKQGKTALAVASRSNHSLVVGMLIKAERYYAWRE----EHHESIRDPSTGFTLTFKQDHSLETRHIRTLLWDLAYHQLKANEWQRLARSWNFTDDQIRAIEEQWSGNESFREHGHRALLIWLHGTLMTQGDPAKQLYEELVHAGFPKLAEKTRHFKSKTDSNSKKCVVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZ15-1", "uniprot_id": "A0A8M9PZ15_DANRE", "id": "A0A8M9PZ15-1", "name": "", "aln": "MQTKPGVFYSTRASKAKSLSKQYSTVYSTMEKKAHALKDYILKQPVWMKENLNPKTWIKTDHSKGFAEFILPKDIGADGGYDNKEMLLETEKDFIEAAKRNNVEGMK-LLGRGVNVNAKNVHGRTALHYAVACRNVEAVDVLLRRRAKLDLQDKHGLTAVHLAAWFGSLEILKLLVQGGADQSIENTEGLNMLHCAAMNNHTDIVAYIIDDLQMGELDKEDQFGNRPFVLAAAHGCVPMLQMLMEEHYNMATMQENQVGDTPLHLAAKHGQREALQLLLENFHIRNEVNQAGQTALYLAADGAHEDCVQTLLEAQCDPNIFTLSRNSPLHPVCERGHFQIVQLLINSGAQINAQNQQMQTSFHLAVRNCHIPVIHTLLEAGCDPNLTDHMGQTALHIAAEMGKVDVVEMILKAGVDLQIRDRQNKTALGVAARGNMVIIVDMIIKAERYFKWKDNLQITNTDAIESLHSESPLTFKLDHSPDTKPVRDIMWDLAYKHLKRNDWKKLAEHWEFTDAQMAAIEEQWTGLNSFQEHGNRMLLIWLHGVLIEESSPSKGLYEGLLASGNSKVAGRMLLHISVVFRVCSDLCL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. . . . ::.*: : . . .* . : * : : .. * :* ** *:.* :*** .*:: *: *: : **:*. * .*****:**. . :.***.** ::*::*: ******.:***** **:*:: :**:.**** :. :*:. ** *: .*: ** *:*.**:: :*:: :: *.:** *** :* * *:: * . *: * :::: *:*.***** **: .:*:** :: ** *: . ::* *: ** ** :*::*:....: : : : :..:**.* * : .*:.:**.* * : :: **.**:**: *:*::** :**** :*: *:*.****.**:*.: ::*.*:******: *:: : : *.. .**** *** :*: :* ::*:***::** ::*::**. *.**: *: ******:* :**:*** * *******.*: : .*:* *** *: :* .::* : . * . ... : ", "identical_positions": 196, "similar_positions": 181, "identity": "33.28%" }, { "cls_id": "homologset.agr.HGNC:32528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00LT2-1", "uniprot_id": "PRCD_MOUSE", "id": "Q00LT2-1", "name": "Photoreceptor disk component PRCD", "aln": "MCTTLFLFS-LAMLWRRRFTNRVEPEPSRVDGTVVGSGSDTDLQSTGREKGPVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2A6-1", "uniprot_id": "A0ABK0M2A6_RAT", "id": "A0ABK0M2A6-1", "name": "", "aln": "MCTTLFLLS-VAMLWRRRFTNRVEPEPSRVDGTVVGSSSETDFQATSREKEPVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00LT1-1", "uniprot_id": "PRCD_HUMAN", "id": "Q00LT1-1", "name": "Photoreceptor disk component PRCD", "aln": "MCTTLFLLSTLAMLWRRRFANRVQPEPSDVDGAARGSSLDADPQSSGREKEPLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:* :********:***:**** ***:. **. ::* *::.*** *:.", "identical_positions": 34, "similar_positions": 14, "identity": "62.96%" }, { "cls_id": "homologset.agr.HGNC:32535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q58FG0-1", "uniprot_id": "HS905_HUMAN", "id": "Q58FG0-1", "name": "Putative heat shock protein HSP 90-alpha A5", "aln": "----------------------------------------------------------------------------------------------------------------------MGFHHVGQAGLELLTSGHPALER-----------------------------------------RPEYLEERRIKEIVKKHSQFIGYPITLFVEKKRNKQVSDAEA--EKKEDKRKKKK---ESNDKPEIEDVGSDEEEE-KKDADKK-KKKSKEKYIDQ-ELNKTKPIWTRNPDAITNEEYGEFHQSLTNNWEDHLAVKHFSVEGQLEE-------------------------------------------------------------------------------------------------------------------------------------------LKDSRRVMKANQKHIYYITGETKDQVANSAFVECLQKHGLEVIYMIELIDKYCVQQLKELESKTVVSVAKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDMLEKKVKKVVVSN---------------------------------------------------------------------------------------CMEDPQRHTNKIYRMIKLGLGVDEYDPTANDINAAITKEMPPLRGGDDTSRMEEVGGSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZQP6-1", "uniprot_id": "A0A8I5ZQP6_RAT", "id": "A0A8I5ZQP6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------WTRGRS-CTLIS--FPTSKT-----------------------------------------EPSLLRN-------------------------VSDDEAEEKE--EKEEEKEKEEK---ESDDKPEIEDVGSDEEEEEKKDGDKKEKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWKEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVQRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISHEMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSAFGDEMVSLKDYCTRMKENQKHIYFITGETKDQV-----------HGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSSCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKA-EADKNDKSVKDLVILLYKTALLSSSFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMPPLEGDDDISRMEEVD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02828-1", "uniprot_id": "HSP83_DROME", "id": "P02828-1", "name": "Heat shock protein 83", "aln": "MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNS-EPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEM---ETDE-PKIEDVGEDEDAD-KKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKA-DADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSLVEDTEDASHMEEVD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15108-1", "uniprot_id": "HSC82_YEAST", "id": "P15108-1", "name": "ATP-dependent molecular chaperone HSC82", "aln": "--MAGETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEVPIPEE--EKKDEEKKDE-----DDKKPKLEEV--DEEEEEKKPKTKK----VKEEVQELEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNIDEDEETETAPEAST---EAPVEEVPADTEMEEVD---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02829-1", "uniprot_id": "HSP82_YEAST", "id": "P02829-1", "name": "ATP-dependent molecular chaperone HSP82", "aln": "--MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEE--EKKDEEKKDEEKKDEDDKKPKLEEV--DEEEE-KKPKTKK----VKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEAST---AAPVEEVPADTEMEEVD---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:: . . . . *.: ..: . : **:: ..*.: :. *::*:* **: : ** * **: : *******:*****. *::***. *::*::*:*:: * *********** * * * :**::*:****: . * :.:**::: : **:* . :*** :.* :*.::*: :** * :.** ::*:. ::* * * :*.:* .:*:***** .::.* .:.:* *:*.***.:** : : . :. :.****. ", "identical_positions": 100, "similar_positions": 98, "identity": "13.76%" }, { "cls_id": "homologset.agr.HGNC:32537", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLF3-1", "uniprot_id": "A0A8I6GLF3_RAT", "id": "A0A8I6GLF3-1", "name": "", "aln": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKS------------------------------------------------------------------------------EDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMT----------------------------------------------------------------------------------------------------------------------------------------------------SLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDE-VTAEELS-AAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58FF8-1", "uniprot_id": "H90B2_HUMAN", "id": "Q58FF8-1", "name": "Putative heat shock protein HSP 90-beta 2", "aln": "MPEEVHLGEKEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNTQEHTLTLVDTGIGMTKADLINNLGTIAKF------------------------------------------------------------------------------QDQTEYLEEMQVKEVVEKHSQFLGYPITLYLEKEREKEISDGKAEEEKGEKEEENKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNTEDITQEEYGEFYKSLTNDWKDHLAVRYF--------------------------------------------------------------------------------------------------------------------------------------------------SVEEYVSRMKEIQKSIYYITGESKEQVANSAFVEQVWKRDSRVVYMTEPIDGY---QLKEFDGKSLVSVTKEGLELPEDGEEKKRMEERKAKFENLCKFMKETLDKKVEMVTVSNRLVSSSCCIVTSTYSWTANMEQIMKA------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57521-1", "uniprot_id": "HS90B_DANRE", "id": "O57521-1", "name": "Heat shock protein HSP 90-beta", "aln": "MPEEMRQ-EEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEISDDEAEEEKAEKEEKEEEGEDKPKIEDVGSDDEEDTKDKDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIPP-------------LEGDDDASRMEEVD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02828-1", "uniprot_id": "HSP83_DROME", "id": "P02828-1", "name": "Heat shock protein 83", "aln": "MP-------EEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAP---------------SLVEDTEDASHMEEVD-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*.**************************** **:************** ***:******:* *.:*** **::********:**:******** :***:*:** ::**:*:** **:****.* :****:**:* .:*::** * :*:.: ::*******.*:: :. ... **.*.**** ::*************.:**::************ *:****: *: ******: ** :*:*:****:**::*****:* *. .*: ****** * :**::.**.************** .***: ** ::***.***:**. **:*** *.:..***.*.****** .*:****:**** ", "identical_positions": 246, "similar_positions": 85, "identity": "32.98%" }, { "cls_id": "homologset.agr.HGNC:32538", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O57521-1", "uniprot_id": "HS90B_DANRE", "id": "O57521-1", "name": "Heat shock protein HSP 90-beta", "aln": "MPEEMRQEEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHG-EPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEISDDEAEEEKAEKEEKEEE----GEDKPKIEDVGSDDEEDTKDKDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEAD-KNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIPPLEGDDDASRMEEVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q58FF6-1", "uniprot_id": "H90B4_HUMAN", "id": "Q58FF6-1", "name": "Putative heat shock protein HSP 90-beta 4", "aln": "-----------------------MSLIINTFYSNKEIFLQELISNASDALDKIRYESLTDPSKLDGGKELKIDIIPNPRECILTLVNTGIGMTKADLINNLGAIAKSGTEAFMEAFQSCAEISMIGQFGVGFYSAYLVAEKV-AITKHNDEEQYSWVSSAGSSFTLHVDHG-EPIDRDTKVILHLKEDQTEYLEERWVKEVVKKHPQFIGCLIAVYLEKEPEKEISDD--EEEKGEKEEEDKD----DKEKPKTEDVGSDEEDDTDKNNKKKTKKIKEKYTDREELNQTKPIWTRNPDDITQEECGEFYKSLTSAWEDHLAVKQFPVE-----------------------EQEENEQLCVHHVWIMDSFDDLMPEYVGFVR------------------------------------------EDKENNKKLDEVFSKISWLGIHEDSINWRHLSELLWSHTFQSGDEMTSLSEYVSCMKEAQKSICDIIGECKEQVANSAFVEQEWKKGFEVIYMSEPIDEYCVQQLKEFDGKSLLSVTKEGLELPEDEEEKKIMEESNVKFENLCRLMKEILDKKVERVTISSRLVSSPCRIVTSTYS----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02828-1", "uniprot_id": "HSP83_DROME", "id": "P02828-1", "name": "Heat shock protein 83", "aln": "------MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNS-EPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEM----ETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADAD-KNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAG--DAPSLVEDTEDASHMEEVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15108-1", "uniprot_id": "HSC82_YEAST", "id": "P15108-1", "name": "ATP-dependent molecular chaperone HSC82", "aln": "--------MAGETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEVPIP--EEEKKDEEKKDE-----DDKKPKLEEVDEEEEE-----KKPKTKKVKEEVQELEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNIDEDE-----ETETAPEASTEAPVEEVPADTEMEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02829-1", "uniprot_id": "HSP82_YEAST", "id": "P02829-1", "name": "ATP-dependent molecular chaperone HSP82", "aln": "--------MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIP--EEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEE------KKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDE-----ETETAPEASTAAPVEEVPADTEMEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******.********:**:************::*:**.:*: :* * : *: * : ::******::*:****:******:*****:.: *::************ :***::* . :* *::*** * *.**.***: *. * :.*.* : *.:*:** :*:** :**::::*.:*:. * : : ** :**:. ::** : :::.: .:** *:*..::: . *.*.:**: : ****:***:*****.**::** . ****::. *** * **:*.** ::.:* :* *::*:* *. ::*:**::.*:: **.:: .*: . *:* **:***: * *:.:* :: * *:: **::**: * : ** : * **. . * :*.*:: :.***:::::***** . :**::.** *:.:**: :** * :.** *:. ::* * : :*.**..:**:*.:* :*:.:*. * *. :. ", "identical_positions": 219, "similar_positions": 176, "identity": "29.96%" }, { "cls_id": "homologset.agr.HGNC:3254", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GH40-1", "uniprot_id": "A0A8I6GH40_RAT", "id": "A0A8I6GH40-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "MGFSFRDKMAPSTPLLTVRGSEGLYMVNGP---PHFTESTVLPREPGKNCKVYTFSKDGTLFAWSNGEKVNIINVANK-----GLLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDGTAGTPNLQLYDVKTGTCLKSFIQ-------KKMQNWCPSWSDDEIICARNVNNEVHFFENNNFNSACFLREPRAMCLKYQEKAPQTCLQSDLIETVPQKVFLDTIANKLHLQKVNDFNLSPGTQPFKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATN------GESAVVQLPKNGPIYDVAWNPSSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLYKYDVPSNGELWQVSWQP--------FLDGIFPAKTITYQAVPSEVPSEEPKVATAYRPPALRNKP-VTSSKLHEEEP------PQNMKPHPSSDKPLSKTALKNQRK------------------HEAKKAAKQ--------EARN------DLAPTPVPQSAPRSTVTQSASGDPEVDK--KIKNLKKKLKAIEQLKEQAAAGKQLEKNQLEKIQKETALLQELEDLELGV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJW6-1", "uniprot_id": "EIF2A_MOUSE", "id": "Q8BJW6-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPSTPLLTVRGSEGLYMVNGP---PHFTESTVLPRESGRNCKVYTFSKDGTLFAWSNGEKVNIINVANK-----GLLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDGTAGTPNLQLYDMKTGACLKSFIQ-------KKMQNWCPSWSDDEIICARNVNNEVHFFENNNFN---------------------------------------TIANKLHLQKVNDFNLSPGTQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTEVDKTGASYYGEQTLHYIATN------GESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQP--------FLDGIFPAKTIKYQAVPSEVPSEEPKVATAYRPPALRNKP-VTNSKLHEEEP------PQNMKPHPGSDKPLSKTALKNQRK------------------HEAKKAAKQ--------EARS------DAAPTPVPQSAPRNTVTQSASGDPEVDK--KIKNLKKKLKAIEQLKEQAAAGKQLEKNQLEKIQKETALLQELEDLELGV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY44-1", "uniprot_id": "EIF2A_HUMAN", "id": "Q9BY44-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPSTPLLTVRGSEGLYMVNGP---PHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVNIISVTNK-----GLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCLKSFIQ-------KKMQNWCPSWSEDETLCARNVNNEVHFFENNNFN---------------------------------------TIANKLHLQKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATN------GESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATIFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQP--------FLDGIFPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKP-ITNSKLHEEEP------PQNMKPQSGNDKPLSKTALKNQRK------------------HEAKKAAKQ--------EARSDKSP--DLAPTPAPQSTPRNTVSQSISGDPEIDK--KIKNLKKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4QRJ7-1", "uniprot_id": "EIF2A_DANRE", "id": "Q4QRJ7-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPPTPHLAVRGSDGTLLLHGP---PNCQESSAFQRDD-RQGRYMTFSNDGTLFAWCNGSQVTVLKVPSG-----DLVKSFDLPKTTALEFSPLNKVLATWQQYTKTQDNPQGEANLQLWDLQTGACMKAFYQ-------KKMTGWCPSWADDESISVRNVNNELHFFENNNFE---------------------------------------TIANKLHLQKVSEFALSPGSQPSKVAVYVPGSKGAPSFVRLYQYPNFGGPTCALANKSFFKADKVNMLWNKKATAVLVTASTEVDKTGASYYGEQTLHYVATN------GESAVVQLPKNGPIYDVSWSPNSTEFCVVYGFMPAKATVFNNKCESVFDFGTGPRNAAFYSPQGHILVLAGFGNLRGQMEVWD-VKKYKQVSKPQAEDTTHFSWCPDGEHIVTATCSPRLRASNGYKIWHYTGTVLYKHETPSGKELWEVLWQP--------FPAGVFPERAVKYQALPSELGSTEAKPAQAYRPPALRNKPQTASSKLHEEEP------PQNMKPGAAGEKQPSKAALKNQKR------------------REAKKAAKQ--------ENKP------DEAPPPAADPAPVSHVTSSC-GDPETDK--KIKNLKKKLKAIDELKEQQAAGKVMQKNQLEKMQKEAQLLKELEDLELGL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNX8-1", "uniprot_id": "EIF2A_DROME", "id": "Q9VNX8-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "----MAAAADLVVPTLAIRSSVAVELWSSAGSKQPFEHKPHLPREETKSSRSICFSSNGRYFAYSNGQEVKVLQASRDSAASWPVICVLPRPKAFYLQFSPRGSYLCTWEHYAITKDRPEGSPNLLVYEVATGVEVFAIVQ-------KNQADWQPSWSADESIFALVVGGEALFYDLGEGAEKG----------------------------------FATTSRKIGGSRGGMLSLGPGNCPPFLAFYTPGAKGAPSMCKLYKYPALG-QNQTVACKSFFQADRVEMLWNKRGSGLLLLTSTEVDKSGASYYGNQAVHFMATK------GDTCSVPLSKEGPVHCVKWSPKATEFVVVYGFMPSKAALYNLKCDVVFDFGEGPRNCAYFNPFGNLIALAGFGNLPGAVEVWD-VSKREKLANLKCADTTVFEWHPNGEWFVTATTAPRLRISNGFKVYHYSGALLHETMWPQGQELLGIEWQQ--------FADKTFSEPKITKAKHEGIKSSQPEASKKAYTPPHLRLLKEGKNPEKYLPQPSIPGLAPTAAAGGVNGNKRNNKNKQRSARKDVNVVNGGDADSAPTEVVDQAAPVARQSPVFVAAEERKPQHTPRQKYQPDNAADQPPNSYGQGHPNGQHISDKERKIRSVAKKLSDIKKLKVRRSQGENLELNQLNKIKMEAQYLDELKALKQSA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53235-1", "uniprot_id": "EIF2A_YEAST", "id": "P53235-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "-----------MSSQFFLKTSQDIELFQSY---PTFEQSNTNSKDFPVISS--VLSPCGRFLALSTKENVKVFTGPCLD----NVLLTMKLSDVYDLHFSPAGNYLSTWERASIQDPNHKNVKVWYLNKPFKKDCVSEDIVPAYEYQAKSQSGWFLQFSKLDNYGLRLFKHDLKIVKLSSANADN----------------------------FDFQSPFAVLSDDETSQHFTTYLISPAEHP-TICTFTPEKGGKPAQLIIWALSEGK-ITKKIASKTFFKADSCQLKWNPLGNAILCLAITDFDSSNKSYYGENTLYLLSFQGVNGTLGGNSVRVSLTTGPVHDFTWSPTSRQFGVIAGYMPATISFFDLRGNVVHSLPQQAKNTMLFSPSGHYILIAGFGNLQGSVEILDRLDKFKCVSKFDATNTSVCKWSPGGEFIMTATTSPRLRVDNGVKIWHVSGSLVFVKEFK---ELLKVDWRSPCNYKTLENKDEAFFENHIINNWEPLPDSTTSSLDPKISNKSELQIHSSVQEYISQHPSREASSNGNGSKAKAGGAYKPPHARRTGGGRIVPGVPPGAAKKTIPGLVPGMSANKDAN-----TKNRRRRANKKSSETSPDSTPAPSAPASTNAPTNNKETSPEEKKIRSLLKKLRAIETLKERQAVGDKLEDTQVLKIQTEEKVLKDLEKLGWKDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: * : . .. :: :* * :* . .:*.:: . :: : .. *.*** .. *.**: : . . : . . : *. .* .:: : . : : . .. . : . .: :.*. * :. :.* * *: :: . :* *:**:** : ** ...:* : *:.*.:. ****::::: :: : * .. . **:: . *...: :* .: *:**:. :.:: : : *..: .:* :.* *: : :****** * :*: * :.: : ::: . ::: * *.** ::*** :**** .** *::* :*:::. ** : *: * : . . *: . . * . : : : . : . * .. .. .. : **:.: *** *. ** : : *. :: .*: *:: * *.:*: * ", "identical_positions": 93, "similar_positions": 181, "identity": "13.29%" }, { "cls_id": "homologset.agr.HGNC:32545", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACQ1-1", "uniprot_id": "D4ACQ1_RAT", "id": "D4ACQ1-1", "name": "", "aln": "MDQNVDQPRQEEPSLRLEKLQHWAKRRHSGHLLVLAVSQLWLAIAVVPFTLSVSCLNSACHLATVLPLWPGASGLLTGIVTLEFRRAPCIWKVRAMMISNTLNLILGFIAVVMEVIKTALGTASADSSQSTGLLVLELSAEAFTLGGVLFSTYALFLLSQRKPGSFKKSRLQYQELQEGLSEVEEVSGLENDPVVASTGN--RTEE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UNB8-1", "uniprot_id": "TM253_MOUSE", "id": "Q3UNB8-1", "name": "Transmembrane protein 253", "aln": "MDQNANQPRQERPSVRLEKLQHWARHKQSGRLLVLAVSQVWLAIAMVPFTISVSCLTSACHLVTALPLWPGASGLLTGIITLELRRAPCIWKVRAMMISNTFNLILGFVAVVIEVMKTALGTASMDSSQSTGLLVLELSAEAFTLAGVLVSTYALFLLSQRKPGYFKRSRLQYRELQEGLSEMEEVSGLENGPVVASTGN--RTDE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7T8-1", "uniprot_id": "TM253_HUMAN", "id": "P0C7T8-1", "name": "Transmembrane protein 253", "aln": "MEDRAGEQEQERHSLRLEKLQHWARHRQSGHLLVLAVSQLWLAVVVVPLAVSVACLNSDCHMATALPLGPGASGLLTGTVTLELRRAPRLWKVRAMMIFNTFNLILGFIVVVVEVMKTALGPAPTASSQHAGLLVLELSAEAFTLGGVLVSVHALFLLSQRKPGCCRSQSLHYQELQEGFSELEEVPGLENGPTVASTGANERVGQREQTRAALLPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::...: .**. *:*********::::**:********:***:.:**:::**:**.* **:.*.*** ********* :***:**** :******** **:******:.**:**:*****.*. *** :**************.***.*.:*********** : . *:*:*****:**:***.****.*.***** *. : ", "identical_positions": 136, "similar_positions": 52, "identity": "62.67%" }, { "cls_id": "homologset.agr.HGNC:3255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1Z1-1", "uniprot_id": "E2AK3_RAT", "id": "Q9Z1Z1-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "aln": "MERATQPRPRA--LLLLFLLLGCAAGISAVARARS--LLAPTSDTAFGLGAAAAPTSAARVP---AVATAEVTVEDAEALPAASGEQESRATESDDDVELRPRGRSLVIISTLDGRIAALDAENHGKKQWDLDVGSGSLVSSSLSKPEVFGN---KMIIPSLDGDLFQWDRDRESMEAVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKLRYICSALGCR------------RWDSDEMEEEED--------------------ILLLQRTQKTVRAVGPRSGSEKWNFSVGHFELRYIPDMETRAGFIESTFKLG--------------------GNKEDSKIISDVEEQD---VDTVIKVSVADWKVMAFSKK-GGRLEWEYQFCTPIASAWLVR-DGKVIPISLFDDTSYTANEEVLEDEED-IVEAARGATENSVYLGMYRGQLYLQSSVRVSEKFPTRPKALESVNGESAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSN------------DKYSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDSPHYSKNIRKKDP--------------------------------ILLLHWWKEIFGTILLCIVATTFIVRR------------LFHPQP--HRQRKESETQCQT---------ESKYDSVSADNSDNSWNDIKHSG---YVSRYLTDFEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLETPPEKWQEEMDEIWLKDEST-DWPLSSPSPMDAPSVKIRQMDPFSTKEQIEVIAPSPERSRSFSVGISCGRTSSSESQFSPLEFSGTDCGDNSDSEDAAHNLQDSCLTDCD-MEDGTVDGDDEGHSFELCPSEASPYTRSREGTSSSIVFEDSGCDNASSKEDPRMNRLHNGHHYVNKLTEFKHSSSRSSSEAT-LSTSPTRPTTLSLDFTRNTVDRLQPSS------PKVYLYIQMQLCRKENLKDWMNRRCSMEDREHRVCLHIFLQIAEAVQFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQ---DEEEQTVLTPMPAYATHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPQEHMMVQDMLSPSPMERPEATDIIENAVFENLEFPGKTVLRQRSRSLSSSGTKHSRQPSSTFSPLPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2B5-1", "uniprot_id": "E2AK3_MOUSE", "id": "Q9Z2B5-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "aln": "MERATRPGPRAL-LLLLFLLLGCAAGISAVAPARS--LLAPASETVFGLGAAAAPTSAARVP---AVATAEVTVEDAEALPAAAGEPESRATEPDDDVELRPRGRSLVIISTLDGRIAALDAENDGKKQWDLDVGSGSLVSSSLSKPEVFGN---KMIIPSLDGDLFQWDRDRESMEAVPFTVESLLESSYKFGDDVVLVGGKSLITYGLSAYSGKLRYICSALGCR------------RWDSDEMEEEED--------------------ILLLQRTQKTVRAVGPRSGSEKWNFSVGHFELRYIPDMETRAGFIESTFKPG--------------------GNKEDSKIISDVEEQEATMLDTVIKVSVADWKVMAFSRK-GGRLEWEYQFCTPIASAWLVR-DGKVIPISLFDDTSYTASEEALGDEED-IVEAARGATENSVYLGMYRGQLYLQSSVRVSEKFPTSPKALESVNGENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSN------------DKYSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDSPHYSKNIRKKDP--------------------------------ILLLHWWKEIFGTILLCIVATTFIVRR------------LFHPQP--HRQRKESETQCQT---------ESKYDSVSADVSDNSWNDMKYSG---YVSRYLTDFEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLETPPEKWQEEMDEIWLKDEST-DWPLSSPSPMDAPSVKIRRMDPFSTKEQIEVIAPSPERSRSFSVGISCGQTSSSESQFSPLEFSGTDCGDNSDSADAAYNLQDSCLTDCEDVEDGTVDGNDEGHSFELCPSEASPYTRSREGTSSSIVFEDSGCGNASSKEEPRGNRLHDGNHYVNKLTDLKCSSSRSSSEATTLSTSPTRPTTLSLDFTKNTVGQLQPSS------PKVYLYIQMQLCRKENLKDWMNRRCSLEDREHGVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQ---DEEEQTVLTPMPAYATHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFSTQMERVRILTDVRNLKFPLLFTQKYPQEHMMVQDMLSPSPTERPEATDIIENAIFENLEFPGKTVLRQRSRSMSSSGTKHSRQPSCSYSPLPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZJ5-1", "uniprot_id": "E2AK3_HUMAN", "id": "Q9NZJ5-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "aln": "MERAISPGLLVRALLLLLLLLGLAARTVAAGRARG--LPAPTAEAAFGLGAAAAPTSATRVPAAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDETELRPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGN---KMIIPSLDGALFQWDQDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCR------------QWDSDEMEQEED--------------------ILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPN--------------------ENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKK-GGHLEWEYQFCTPIASAWLLK-DGKVIPISLFDDTSYTSNDDVLEDEED-IVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVTNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSN------------DKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDP--------------------------------VLLLHWWKEIVATILFCIIATTFIVRR------------LFHPHP--HRQRKESETQCQT---------ENKYDSVSGEANDSSWNDIKNSG---YISRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDEST-DWPLSSPSPMDAPSVKIRRMDPFATKEHIEIIAPSPQRSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCD-VEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEAT-LSISPPRPTTLSLDLTKNTTEKLQPSS------PKVYLYIQMQLCRKENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQ---DEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3B8-1", "uniprot_id": "A0A8M2B3B8_DANRE", "id": "A0A8M2B3B8-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "aln": "MERGFQFGNVCISLLLLLVLRTLTATLQTQSLSEREVEVAPTPNTEAAEHAAVMERPLDNVG--GALGIGEVTVEDDDYGSTG----DSDEPSGDTDANFHKHRRALVIISTLDGRIAALDPLNQGRKQWDLDVGSGCLVSSSLSKPEIFGN---KMFIPSLDGALFQWNRDRESMEAVSFSVESLLDSSYRIGEDTVLVGGKSLTTYGLGAYSGKLKYICSAVGCS------------RWG-DEEGEPED--------------------VLLLQRTQKTVRAVRPRNGFEKWNFSVGNFELKFVPEIQSKLNFLEGEAPSGETWREVRREAQRVIQEETDAQTKNHAKMHPNSAHTQVEGLDLVIKVSVPDWKVMAFSTKPEGQLIWEHQFCTPIASAWLVG-GGKVTPISLFDDTSYNSQTETETQEDDDIMEEARGATESSVYLGMFQGQLYLQSSVRISEKFPSKSKALNGWGGDTDMMPPPTVKWKPLIHSPSRTPVLVGSEEFDKCLNN------------DKFSHEEYSNGALSILQYPYDNGYYFPYSPRYRNRRDETAVSVLLKKDGEGSQVRRKDP--------------------------------VLLLPWWKEILGTIFFCIAATTYIVRK------------FFHPPTTYSRQRKESETQCQT---------DTKFEADVTEPKEVVVTDMRPCE---YVSRYLTDFEPVQCLGRGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIIRYFNAWQESPPQGWQEDMDKRWLKDASTADWLLSSPEHMEAFSVKVP------------VATPSPVDSSCMCA--AGGDTSVCVGDQVCVEGLGPDSMMSERDSQADP--------------DAIMEVSDSPHSFELCPPRTVAHG-DCTSSSFDIVFEDSGCEHQDNDSDLSGSTPVP----PVCLSQSGSKPQRSTSTGPPISLP-SRPTTLSLAPSTPCPVVRPLLT------PKVYLYIQMQLCRKENLKDWMAQRCLPELREHTQCLDIFLQIAEAVDFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQEE-DDEELSTLTPMPIYARHTGQVGTKLYMSPEQLSGNSYSHKVDIYSLGLILFELLCPFRTQMERVRTLTEVRALQFPAAFCKANILEAQMVRCMLSRVPAERPEASEITEAPLFQELEVPCRIRQRTRTYSASSAG-RPSRQISSSN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NIV1-1", "uniprot_id": "E2AK3_DROME", "id": "Q9NIV1-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase", "aln": "-MQDDLDGIVRHRRRSLSFLQIVTLTMAGLVAFDPAQVLAGHPTTDSELQTAGSPR--------------------------------PPGLEHCVDQEERRVARRLLYISTLDGRLSALDIAKSGKLRWSVPTGPGPLISSSIHRLELTNNGQFVRMIPSLSGGIYKFDGD--SIDPIPITAEHLLSSSAKFSDDLVISGGKETRSYGVSVRTGQLLYECSLNGCVNSTEEGLAIDDTIREPDEEDQLEDGEQLRDEAGYIVRHDPLLDDVIIVRRQTQTVRAVESRTGVERWNFSVGQHELDLVRPSECQLQPRD---------------------------------------ELELAVLDVDIKVVVPEGIICAFSKSEPQTMLWKYKFDHPIVSAWNTNADDELQPIDLFSSAQWLWDQDENDTELP-----NAPQSPPSIYLGMYDKQLYIQESIRLRQEIMDQTKVYQQLTGDTSLMPR--IPWKPISASSKSLVIFRKDQEDPEMIAEGAVAQGGELVPYDDENFAVAAQSVLNASEFVNGNGFYFYTTGDLNGPQECSTQNNPTDLPAITAPTSPTNATSEGTEATGNHSVNDDLGFSLDDIDAPVKVVILSLWFWWKEIVVIAFTSAVILNIFMGQRNQRVEREYLVIERHVPVQTAIEATEASTQALLGPVVPMQRPGNRFSFPPGQANQRTISESTTHSGEHYTSRFQSDFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSRQRVLREARTLASCEHHNIVRYFHSWTETPPTGWQEEEDRKLLAHELSTSIQIETPDDSTMPSLTEQLKEKRQQQLLSWVSDAANSTACSHDFHLPGESSLKNIREEYDYDEEEDSLIEFRSESQSAALR-------------AEEEDDTDDDYEEDEEQQGDHEKRHRSSVSIDIHSASFDLKNINYSQHQLVSNSFQIESVRPKSSGSDDANDDNKARRKPLTLALAQNHNNNQNGSQPTPSSATILNGTVAKPSKVYLYIQMQLCRKESLRDWLRD--NRSETRAAHIGDIFHQIVDAVDYVHLKGLIHRDLKPSNIFFSQDGQIKIGDFGLVTDMADIPNLVAKCGDQSGLPSCARHTQQVGTHLYMSPEQLLGQHYDYKVDIYSLGLIFFELHVYFSTEMERIKTLRSLRDGQYPKDFAVNYPQQYDLLQQMLSAQPEQRPQTKQLKSQLRNILQLPHLLSEGQSEQAELAERARRLSRSRTFSSSSEPHQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .* : * . : :* . . : : : * *: *******::*** : *: :*.: .*.* *:***: : *: .* :****.* ::::: * *::.:.::.* **.** ::.:* *: ***. :**:.. :*:: * ** ** ** : ** :::::* :***** .*.* *:******:.** : : : : . : :* *** *.: : *** . : *:::* **.*** ..:: **.**..:.: . : * : *:****: ***:*.*:*: ::: .*. : .:. ::* : ***: *.. :: .:* : : : *. .. ::..*. :: .**:*: .. :. . .:. : * *****. : . . :: : * : .*:.**. .::. : .: .: * **: :*** :**:***********:**:*: .****** ***:* :*::*:**.::**. ** .*:***::* *:** ***. *. * . : . :.:*. *:. : .: : . . : : : . . :: . : . . . * . * .* . . : . ... . : . ..: :: . .: . . : . .**************.*:**: . . .** **.:**:::* ***:***********: *. :*:******* * : : : :* * ** ****:*******: *: *.:****:*****:*** * *:***:: * .:* ::* * : ::: *** * :**:: :: . : . . :. . : **. . : ", "identical_positions": 277, "similar_positions": 297, "identity": "22.02%" }, { "cls_id": "homologset.agr.HGNC:32550", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBS3-1", "uniprot_id": "ZBT42_RAT", "id": "B1WBS3-1", "name": "Zinc finger and BTB domain-containing protein 42", "aln": "--------------------------------------------------------MEFPEHGVRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDQPASSRDTVRLNGDIVTVPAFSRLLDFMYEGRLDLHSLPVEDVLAAASYLHMYDIVKVCKGRLRKKDPDLETRTLGT-ELPGQTPHPLPSWPPAFCQATPKAKPPSLGVKAVHPLPKFGPPSWQVSEESSGALDLSLKPGPRPEQAHPPCLLQTSQCSSIQQGAQPLVKAEQDSFSEQDSSSPQSADRSPP-PVCASAARG---------LAVNLEPLHIQGTGSQQLGLHAEPVVDSEDLGP--------------GRHLCICPLCCKLFPSTHALQPHLSAHFRERDSVRTRLSPEGAVPTCPLCSKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHAVVHTREKPHACRWCERRFTQSGDLYRHVRKFHYGLVKPLLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q811H0-1", "uniprot_id": "ZBT42_MOUSE", "id": "Q811H0-1", "name": "Zinc finger and BTB domain-containing protein 42", "aln": "--------------------------------------------------------MEFPEHGVRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDQPASSRDTVRLNGDIVTVPAFSRLLDFMYEGRLDLHNLPVEDVLAAASYLHMYDIVKVCKGRLRKKDPDLETRTLGT-ELPGQPPHPLPSWSPAFCQAAPKAKHPSLGVKATHPLPTFGPPSWQVAEQSSGALDLSLKPSPRPEQVHPPCRLQTSLCSSVQQVAQPLVKAEQDSFSEQDSSSPQSADRSPP-PVCASAAQG---------LAVDLEPLHIEGTGSQQLGLPAEPVLDSEELGP--------------SRHLCICPLCCKLFPSTHALQLHLSAHFRERDSVRARLSPEGSVPTCPLCSKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHAVVHTREKPHACRWCERRFTQSGDLYRHVRKFHYGLVKPLLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RXF5-1", "uniprot_id": "ZBT42_HUMAN", "id": "B2RXF5-1", "name": "Zinc finger and BTB domain-containing protein 42", "aln": "--------------------------------------------------------MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQEKDRSLDPGNPAPGAEPAQPPCPWPVWTADLCPAARKAKLPPFGVKAALPPRASGPPPCQVPEESDQALDLSLKSGPRQERVHPPCVLQTPLCSQRQPGAQPLVKDERDSLSEQEESSSSRSPHSPPKPPPVPAAKG---------LVVGLQPLPLSGEGSRELELGAGRLASEDELGP--------------GGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HQ89-1", "uniprot_id": "A0AC58HQ89_DANRE", "id": "A0AC58HQ89-1", "name": "Zinc finger and BTB domain-containing protein 18", "aln": "MHLFKAAWLVFEMGLDLLLFVYKCVLKSTCHEWPPSVYLTSSFSCFFFPARFSSIRMEFPDHSRQLLQCLSQQRQQGFLCDCTVLVGETRFRAHRAVLASCSMYFHLYYRDQLD-KRDVVLLNSDIVTVSAFSLLLEFMYEGKLEFSAIPVEDVLAAASYLHMYDIVKVCKSKLKEKELLPEEQQKAN----------------GVNYVAETCVLTAGKTKAHVSSSAS---SQRSRDDTDCALDLSLKPVWIGEFSG-----QLALDSQ-QQDTQTLVKEQHDVLSEQEDADPASPESRRFGNNGRSAAVTGFSELFPRNKHEDLMEEELSGVRSQRQ-LGDSEGDDEEDLASSDISTSSGVLLSSAGAQVCVCPLCSKVFPNPHVLQLHLSSHFREKDGVRSKLSPDGSVPTCSQCGKTFSCMYTLKRHERTHSGEKPYTCAQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCGLVKTLAIG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:*. :** * ***: ***********::** *******:**:****:***: .**.* **.****..**. **:*****:*:: :**********************.:*::*: : . . .: .. .. .** . . : :::. *******. * * . *. * :*.*** ::* :***:.:.. . .** .* :.* *:. * ..::*.. . :*:****.*:**..*.** ***:****:*..*::***:* .***. *.***** ******************.***************:***********:***************:**** ****.* : ", "identical_positions": 212, "similar_positions": 93, "identity": "42.23%" }, { "cls_id": "homologset.agr.HGNC:32554", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SWY7-1", "uniprot_id": "FA83G_MOUSE", "id": "Q5SWY7-1", "name": "Protein FAM83G", "aln": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELSRIVEAIEVYDPGSEDPRVSGRRPEPQDNGGADASEETSAAGGPPAT-ETLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQPHIKEVVRKMVSQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGVLAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSQSVSLKDIPMEKEPEPEPIVLPSVVPLVPTGTMAKKLVNPKYALVKAKSVDEIAKSSSDKQEVTRPPGLRGPAVAERPGDLSELLPPVHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPN-------IWNPQPNQMNRIKIRDTAHASAQHQLWK-----------------QSQGA--------------------------RPCPAPCPPPAPRDSQ----------------------------------------------------------------GVVPAENGFPQGNPEPQAPVP-------------KPRTVPVASVLARDG---------------------------------------SDIGWALDTPEKE----------------------TPQNGIDPRLPST-----------ASESEVPQQQHSSMTQDDPDGLERGLPNGLDEDED---------------DDDDYVTLSDQDS-----------------------------------------------------------------LSGSSGPGPGHRRPSV----------------------------------------ASSMSDEYFEVRERSVP----------------LQRRHSEQMANGPGHPPRRQLSAPHVTRG--------------------------------------------TFGGPLSSPLWAQGRSREDVDAS-RIQGQRPMDRQAQGQHFHRHGSTTSRT---------PGPPRFRPAADGTQSSS----------------KKASPAAAGPHHWQ--------PKGSPTPRMLPDPGSPRPTRN-------------------------TRLRAELRATEEHAS----------PFGIPYSKLSQSKHLKARAGGSQWAP-------------SDSKRRA---RDHKEP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZN30-1", "uniprot_id": "D3ZN30_RAT", "id": "D3ZN30-1", "name": "", "aln": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVAQGRDAFYEVLKRENIRDFLSELELSRIVEAIEVYDPGSEDPRVSGRRSELQDNGGVDASEDTSAAGGPPATAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQPHIKEVVRKMVSQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGVLAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSQSVSLKDIPMEKEPEPEPIVLPSVVPLVPTGTMAKKLVNPKYALVKAKSVDEIAKTSSDKQEVTRPPGLRGPAVAERPGDLSELLPPVHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPK-------IWNPQPNQMNRIKIRDTAHASTQHQLWK-----------------QSQGA--------------------------RPCPEPCLPPAPRDSQ----------------------------------------------------------------DIVPAENGFSQGNSEPQAPVP-------------KPRTVPVASVLAQDG---------------------------------------SDIGWALDTPEKE----------------------TPQNGIDPKLPST-----------TSESQVPQQQQLPVTQDDPDDLETGLPNGLYEDEDE--------------DDDDYVTLSDQDS-----------------------------------------------------------------LSGSSGPGPGHRRPSV----------------------------------------ASSMSDEYFEVRERSVP----------------LQRRHSEQVANGPSHPPRRQLSAPHVTRG--------------------------------------------TFGGPLSGPLWAQGRGREDIDAS-RIQAQRPVDRQAQGQHFHRHGSTTSRT---------PGPPRYRPAADGTQSSS----------------KKASPATAGPNHWQ--------PKGSPTPRMLPDPGSPRPTRN-------------------------TRLRAELRATEEHPS----------PFGIPYSKLSQSKHLKARAGGSQWVP-------------SDSKRRA---RDHKEP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6ND36-1", "uniprot_id": "FA83G_HUMAN", "id": "A6ND36-1", "name": "Protein FAM83G", "aln": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGPSQGPEDNG-VGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDPN-------IWNPQPSQMNRIKIRDTSQASAQHQLWK-----------------QSQDS--------------------------RPRPEPCPPPEPSAPQ----------------------------------------------------------------DGVPAENGLPQGDPEPLPPVP-------------KPRTVPVADVLARDS---------------------------------------SDIGWVLELPKEE----------------------APQNGTDHRLPRM-----------AGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEE--------------DDDDYVTLSDQDS-----------------------------------------------------------------HSGSSGRGPGPRRPSV----------------------------------------ASSVSEEYFEVREHSVP----------------LRRRHSEQVANGPTPPPRRQLSAPHITRG--------------------------------------------TFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKD---GFPGPPRYRSAADSVQSST----------------RNAGPAMAGPHHWQ--------AKGGQVPRLLPDPGSPRLAQN-------------------------ARPMTDGRATEEHPS----------PFGIPYSKLSQSKHLKARTGGSQWAS-------------SDSKRRAQAPRDRKDP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F4B5-1", "uniprot_id": "E7F4B5_DANRE", "id": "E7F4B5-1", "name": "", "aln": "MALSQVQCLDDNHINARTNESKPEFLYSEGQRLALETLIHAGRDAFEDYIKTNSIRCFLSDLELERIFGTAEVYSPGSPQNNAEVYWE--------GDGEEIS--------------LQYWPDRSDRSIPQLDIGWPDRASYRGVTRVQVYTQPPYEGQSHIKGVVRKMIGQAQKVIAVVMDLFTDIDIFKDLLDASYRRKVAVYIMLEATGVKHFMRMCEKAGMHTGHLKNLRVRSIRGAEFLSRSSKRVYGSQSQKFMFIDGDKAVSGSYSFTWSASRLDRNLITVLTGQAVDTFDTLFQDMYMLSNGVCLSKINLSSEPEPE-YVPQAVPTPLPSATKALKLINPKYTLVSNC-AFTTNGPVSDQTSAQNSTSKN----QTEVVKVTPVVPPVHPGLLNLEKADMINYIPTWPDPDPP--SDVIGFINIRDANKPLQAHLMRSELFEVSQAIRFKDPVHEPVESSFLRASPGPVSQTSSHPEVPAQKQTPGEAQMDFDKNQHQTSNQSENLVLPLEKPKMMHVLAFNKVDKEEPCVSEKDLDTKSLQSKNICTKKDFAKAISSFQDDTVSDTKGIQDTLQPLNCSNHTSEELYWKSSAVSNKSDLVESFAIPKSPSVKQSQDDQIITDVVTQNHIETKPETNQNGWNGTKMSNCDSSMSSLSDEYYECFSPVADFRSVEDIFVPEETRESLPNPIKKGHQGQAILRSKSCPAQDCEDLGNSQNYFTPKLLKTSCSIIFNFLSAECKTTAALSKTTFAQENDKGAIINDSKQPVKDSESCCFLQTPNGYLNFSLTSDEYFECSDTVGLKSEIDCVVSKELSSAENINEPQRITKLILEAEKLPELGCQNIKEKVEPEMHSGQEQPEFQHVLHMTADSNLPDGSRAVLLSEDNTQAQSNDKLLKQVQDSEVTSKPAVDTESMSSVLQQHMARASQQFLERQTKAVSVELTEKMSIQDLQIESLQEVLPHASQNINSKDKFVLFDKRNSNPEFESEVSVDVVCEEHFVKSLQDLQPELSSDLIPKPPEVNKVADKMAMQDLQLKASLNLMCEGSKKESVQGLQPNASLDLIGEVKPLWSSKKNSESGFVSEVSVDLVCEEQSVQTLQDLHPGSSSDLQLKTSEVNVCVEKSEKKAMQDLQLEEGLDLVCEESEKESLQGLQPDTSLGLTGKENPLLLAKKISNPNLECEVNRDVACEEKSVKSLQDLQPEPSSNLLLKPTEVNVSVEVAENNAMQDLQLKVSLEESEKESPQGLQPTAITLIDEEKPLLLAMKHSDSGFLSEVSVDVVCEEHSVKPLQDLQPEVSLDLMLKPAEGNVILHYATDSVFNCSILQDKADVTSVIPEKPEITKLIELPKIKELQKSLTCLDCSSKHQHNLRSEEDVNEHLRLPNDEVSQAVLKIKSEQHNSQMKIPEQFESIELLILEDSDLQMTEQDQSDPGSPIVALSKETKICKTKPIQMKTTIDRKLTEEKLGHEVYSRNGKETCYPTAPDEEKQEGEHICTNQTYKNLPEAKPKMESLARKHSLQTSSRIPIQARRGSTKLPIGKLDTSNCSSGLQAPKCGIHKQLPGKPMGQKKTSITPPSSPEKPSIGKITPVRPTQIPQRPTWTVPTPNSPTSPTNQNQQTAPRIKPPDQPNVSRSASMTKYSRSSYEISCTRQVKKQAVKGILPSP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BI56-1", "uniprot_id": "A0A8M2BI56_DANRE", "id": "A0A8M2BI56-1", "name": "", "aln": "MALSQVQCLDDNHVNWRLNESKPEFFYSEDQRLALESLATKGRDAFDAFVKERELRPFLSEPELEMFRRSIEEYKPGSEHQKQDGMTE--------GEDRAVS--------------LQYWPDRSDTSIPNLDLGWPDCNSYRGVTRVNVYTQPPIDGQTHIKEVVRKAIAQAQKMIAVVMDVFTDVDIFKDLIEAGFKKKVAIYIIIDNAAVQHFLLMCERANMHKGHLNHLRVRCIGGSEFYTRSAQKVRGSLSQKFMFVDGDRAVSGSYSFTWTASRLDRNIITVLTGQAVETFDKQFRELYMSSRGVNLSKIPMAEPPEPE-PIPVAVPPPVP-VNVARKMINPKYALVN---ADASSKASSDKASAKNSNTPNPMVQLPKPQRELPEAPPKHPGLVGLPKADLILYLPIWPEPDPS--SDVIGFINIRDTSKPAQVHLMRSQMFETSQAIRFKDPFTAPPEDPLP------------------EKATP--------------------------RPKATQLPKINAVEPN------------------------------------------VQSVPQPQ------------PDSSIANQDTPANTSQTPNSPDQQQDP---------KPNPPAQEPEPNPE---------------------------------------PVEVQQAVEIPVPKPRTLQLVVN-----------MSEGSGDAEVTLVKR----------EENQTIGSKDAHLDLQDNDADSTAVTCAHSLKDKD------------ENSTTSDEYYECTDSDG-------------------------------SDKLPNG--------------------------RITGSGRVGDHSPDALN---------------------------------------VMARFSQSMLDLRSDDP----------------DLRSTVEKNRLNAQSRDKAKLYKTVSRSP----------------------------------------------VRDTYGRAKLVIGKPGGFHR-----HPKSSDHLIGGHR-YWQGKMYAPE------------PPSNGSDQQNLHRSG----------------RSPRRQNPGCRIER------LQTSQTPAQRLMHTQTLSPARR-----------------------------VSQTKSLSPHRR-----VETRTPLGIPLSKYASFKHLKAKVPVNTS-----------GFALGDK----LLTQRHKDN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**********:* * .******:*** ******:* ***** :* ..:* ***: **. : : * *.*** . . . .. * *:***::** ***:**:**** :******..** *** :**.*** **** :.****:******:***:******::*.:::***:**::: : *::*: ***:* ** ***::****. *:** :**: :. * :*****:***:**.*******:*:* ***:*:**:**.*: ** *:::*: *..* *. * : . **** : :* . :* . * *::****:**. . *:: .. .. . . ** ****: * :*::: *:* * :*** **::*:*** *.. : . . : *:::*. . : : :. . :* : . :. :. : * .* . . : : : * : .. * . . ::* : : : .*:* :* . :... : *:. :: : *: . * . . . . . : : . . . : : :. : . :. . . . .. : : . : . . ..: :: :.*: :. . *. :.: ", "identical_positions": 217, "similar_positions": 205, "identity": "12.98%" }, { "cls_id": "homologset.agr.HGNC:32565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQF4-1", "uniprot_id": "JUNO_MOUSE", "id": "Q9EQF4-1", "name": "Sperm-egg fusion protein Juno", "aln": "MAQWWQILLGLWAVLPTLAGDKLLSVCMNSKRHKQEPGPEDELYQECRPWEDNACCTRSTSWEAHLEEPLLFNFSMMHCGLLTPACRKHFIQAICFHECSPNLGPWIQPV-------VPNGQEEQRVWGVPLCQEDCEDWWRACHSSLTCKSNWLHGWDWSEEKKHCPAHEPCLPFSYHFPTPDDLCEKIWNNTFKASPERRNSGRCLQKWFEPTLSNPNVEVALHFAGSALAPQLSYTLPAFSLCLLFHP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M928-1", "uniprot_id": "JUNO_RAT", "id": "F1M928-1", "name": "Sperm-egg fusion protein Juno", "aln": "MAQWWLILLGLWTVLPSLAGGKLLNVCMNSKHHKQEPGPEDKLYFECMPWKDNACCTRDTSWEAHLDEPLLFNFSMTHCGLLTPLCHKHFIQAICFYECSPNLGPWIQPV-------VPNRQEEQRLWDVPLCLEDCEEWWKDCRTSHTCKADWLHGWVWDQGKNGCPAHAPCLPFSDYFPTPADLCEKIWNNTFKASPERRNSGRCLQKWFEPTHGNPNVEVALHFAGSASAPQLSYSITAFSLCLLLHA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6ND01-1", "uniprot_id": "JUNO_HUMAN", "id": "A6ND01-1", "name": "Sperm-egg fusion protein Juno", "aln": "MACWWPLLLELWTVMPTWAGDELLNICMNAKHHKRVPSPEDKLYEECIPWKDNACCTLTTSWEAHLDVSPLYNFSLFHCGLLMPGCRKHFIQAICFYECSPNLGPWIQPVGSLGWEVAPSGQGE-RVVNVPLCQEDCEEWWEDCRMSYTCKSNWRGGWDWSQGKNRCPKGAQCLPFSHYFPTPADLCEKTWSNSFKASPERRNSGRCLQKWFEPAQGNPNVAVARLFASSAPSWELSYTIMVCSLFLPFLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** :** **:*:*: **.:**.:***:*:**: *.***:** ** **:****** *******: . *:***: ***** * *:*********:************* .*. * * *: .**** ****:**. *: * ***::* ** *.: *: ** ***** :**** ***** *.*:********************: .**** ** **.** : :***:: . ** * : .", "identical_positions": 154, "similar_positions": 45, "identity": "61.35%" }, { "cls_id": "homologset.agr.HGNC:3257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64270-1", "uniprot_id": "EI2BA_RAT", "id": "Q64270-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEDG---ELIKYFKSQMKGDPNMASAVAAIQTLLEFLKRDKGETIQGLRAHLTKAIETLCAVDSSVA-VSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLSRISLSRTKIASLCHAFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKVDLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSVQAGQDLKEEH--PWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC8-1", "uniprot_id": "EI2BA_MOUSE", "id": "Q99LC8-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEDG---ELIEYFKSQMKGDPKMASAVAAIQTLLEFLKRDKGETLQGLRANLTYAIKTLCGVDSSVA-VSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKIANLCHTFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALSHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQEDVPDKFKYKADTLKSVQTGQDLKEEH--PWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14232-1", "uniprot_id": "EI2BA_HUMAN", "id": "Q14232-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MDDK---ELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVA-VSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEH--PWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILD9-1", "uniprot_id": "A0A0R4ILD9_DANRE", "id": "A0A0R4ILD9-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEER---ELVEYFRGQIREDPDVASAVAAIRSLLEFLKRDQSETILGLRENMTQAIHRLQEADSSVA-VSSGGELFLRFISLTSLEHPDLSQCKNVMIERGELFLKKISLSRGKVGKLCHTFIKDGAKILTHSSSRVVLKVLENAAADNKRFTVYVTESQPDSAGKLMAEKLRKLSIPVTVVLDAAVGYILEKVDLVIVGAEGVVESGGVINKIGTYQMAVCSKAHNKPFYVVAESFKFVRLYPLNQQDVPDRFKYKADVLK---TAEDLNQEH--PLIDYTPPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAD4-1", "uniprot_id": "Q9VAD4_DROME", "id": "Q9VAD4-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "MPQITENGQDFDVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAGELFCRFITLS-LDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDLPNEYKYSRKHLN------DVSKVH--PLVDYTPPVYITLLFTDLGRLTPSAVSDELIKLYM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14741-1", "uniprot_id": "EI2BA_YEAST", "id": "P14741-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "---MSEFN----ITETYLRFLEEDTEMTMPIAAIEALVTLLRIKTPETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLYGDWENCKQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLP----MAGPPLDFTRRTDDLEDALRGPTIDYTAQEYITALITDLGVLTPSAVSEELIKMWYD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : * .:: :***.:*: :*. . * : : : : . . : :. ::* **: . .:*:: :::.*::*: : ** :.. ** *. **.*. **.*: * * * :*:. .. *: : * .: *:::*:*.* :::..* *:****.*.*.**:** :** :.: :: .*****::**.** *::**.. *:* *. *:.. * :***. ** *:**** *******:****:: ", "identical_positions": 86, "similar_positions": 97, "identity": "27.22%" }, { "cls_id": "homologset.agr.HGNC:32576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "J3KML0-1", "uniprot_id": "J3KML0_MOUSE", "id": "J3KML0-1", "name": "", "aln": "----------MAAKRILVYRNGDAFFPGHQLVVTQRRYPTMEALLYEVTSAVQAPLAVRVLYTLSDGHPVTNLADLQNGGQYVAAGFERFHKIQSLG----DP---------SPYLAVLC---------------LSVFRNGDLLSPPFSLKLSQTAIQDWDTVLKLLSEKVTLQSGAVHKLCTLEGLPLSTGTALVNGHYYVAVGEEEFKALPYMELLVPSPSLSRGCWCPPGLKYKAHRKRVQGYKASAAQP------FPKEPGETGPSTFYARPQ---QPWSKLPALSSPSGVTGVYG-------APYPRKETAGAQEVNEDENTRTEEPVDQPAKAL--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2VCK2-1", "uniprot_id": "DCD2B_HUMAN", "id": "A2VCK2-1", "name": "Doublecortin domain-containing protein 2B", "aln": "-----MAGGSPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQP------SPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPSGVIGVYG-------APHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISASAPALPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0BNA7-1", "uniprot_id": "EIF3I_RAT", "id": "B0BNA7-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVS-----------FFDLRDPSQIDSNEPYMKIPCNDSKITSAVWGPLGECIIAG----HESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTSLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA---------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: *:** :*. : :.: :.. * . . * .* . : . . : . : . .. : ::. : * * : : .:: * :*:. : .:* * * : : *: . .:* **. : : :: ::..* . . : ... : : : : .: . .* :: :* :*. . . * * :* * :. ::*. : . : .: ", "identical_positions": 27, "similar_positions": 90, "identity": "7.36%" }, { "cls_id": "homologset.agr.HGNC:3258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62818-1", "uniprot_id": "EI2BB_RAT", "id": "Q62818-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MPGAAAKGSELSERIESFVETLKRGGGRRTSEDMARETLGLLRRLITDHHWNNAGDLMDLIRREGRRMTAAHPPETTVGNMVRRVLKIIREEYGRLHGR----SDESDQ--QESLHKLLTSGG---LSEDFSFHYAPLKSN------IIEAINELLVELEGTTENIAAQALEHIHSNEVIMTIG-FSRTVEAFLREAAQK-RKFH-VIAAECAP--FCQGHEMAVNLS-EAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG-SLRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFISNIGGNAPSYVYRLMSELYHPDDHVL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LD9-1", "uniprot_id": "EI2BB_MOUSE", "id": "Q99LD9-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MPGAAAKGSELSERIEGFVETLKRGGGQRSSEDMARETLGLLRRLITDHHWNNAGDLMDLIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGR----SDESDQ--QESLHKLLTSGG---LSEDFSFHFAPLKAN------IIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG-YSRTVEAFLKEAARK-RKFH-VIVAECAP--FCQGHEMAVNLS-KEGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG-SLRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFISNIGGNAPSYIYRLMSELYHPDDHVL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49770-1", "uniprot_id": "EI2BB_HUMAN", "id": "P49770-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGR----SDESDQ--QESLHKLLTSGG---LNEDFSFHYAQLQSN------IIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG-FSRTVEAFLKEAARK-RKFH-VIVAECAP--FCQGHEMAVNLS-KAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG-ALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76863-1", "uniprot_id": "O76863_DROME", "id": "O76863-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MKEQPLK--EITQLIHAIKVGLVEG-----SYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQETVTSNIARRILKLTREEFDLLHAKVQHFADDSQA--SLSLHKLVTQTSESNVSVDYSVPQHGLREA------LLDHLQEVETELETSSENICVQAEEHIHSSEIILTLG-HSRSVENFLKRAIKK-RQFLTIIVAECAP--ACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHSVLANG-GLRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIPYDS-IPAREAKVYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLTELYHPEDLEI-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32502-1", "uniprot_id": "EI2BB_YEAST", "id": "P32502-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "MSSQAFTSVHPNAATSDVNVTIDTFVAKLKRRQVQG-SYAIALETLQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSSGSSSMKTKTDYRQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLA-QHNIETLVVPDSAVFALMSRVGKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGGSQRILPRMD--PRKRLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQIDVHLDKNKA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. *. : * . * :: :** :: :* *.:.. *:: :* . : * * .*: **:* : *:* : . *:.:*: . . . * :: :: :::: *:: *.* * : **. *:::* *::* ** * .: .: ::.:* * ..*::* .*: : .:* *:.*:*:**:****.******::::.** : : *. ::. .*:.. .*::. * ::**** . : : * . .: ::* . .. .. : *****: : ::*:* ** **::**: : *: * : ", "identical_positions": 81, "similar_positions": 122, "identity": "21.04%" }, { "cls_id": "homologset.agr.HGNC:32583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V670-1", "uniprot_id": "G3V670_RAT", "id": "G3V670-1", "name": "Methionine aminopeptidase", "aln": "MAAPIGVHLLVRGGCQRILS--SPLHHLFLHKRAGSQ-QRR-YFFWRQRDISHSVVSPAAVSPAHPVPEHIKKPDYVTTGIVP-DWGDSIEVKNEDQIQGLREACRLARHVLLLAGKSLKVGMTTEEIDALVHREIIRRDAYPSPLGYGRFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDESGTKLVEVARACRDEAIAACRAGAPFSVIGNTISHITRQNGLQVCPHFVGHGIGSYFHGHPEIWHHANDNDLPMEERMAFTIEPIITEGSPEFKVLEDAWTVVSLDNRRSAQFEHTVLITPRGVEILTKVPQEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPW9-1", "uniprot_id": "MAP12_MOUSE", "id": "Q9CPW9-1", "name": "Methionine aminopeptidase 1D, mitochondrial", "aln": "MAAPIGVPLLVRGGCQRILS--SPLNHIYLHKRSGSQ-QRRHFFFWRQRDISHSVVSPAAVSPAHPVPKRIKKPDYVTTGIVP-DWGDSIEVKDEDQIQGLREACRLARHVLLLAGKSLKVDMTTEEIDALVHWEIIRHDAYPSPLGYGRFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDESGKKLVEVARRCRDEAIAACRAGAPFSVIGNTISRITHQNGLQVCPHFVGHGIGSYFHGHPEIWHHANDNDLPMEEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEHTVLITPRGVEILTKLPQEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UB28-1", "uniprot_id": "MAP12_HUMAN", "id": "Q6UB28-1", "name": "Methionine aminopeptidase 1D, mitochondrial", "aln": "MAAPSGVHLLVRRGSHRIFS--SPLNHIYLHKQSSSQ-QRRNFFFRRQRDISHSIVLPAAVSSAHPVPKHIKKPDYVTTGIVP-DWGDSIEVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMTTEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDEAIAACRAGAPFSVIGNTISHITHQNGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDLPMEEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEHTVLITSRGAQILTKLPHEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBS4-1", "uniprot_id": "MAP12_DANRE", "id": "Q4VBS4-1", "name": "Methionine aminopeptidase 1D, mitochondrial", "aln": "MAAPCAAQCLYRTGGLRLLQRISRLPHCHKDASLAHQCQFHRSFFWRKPKTSHSVVRPAIVRPAYPVPKHIQRPDYVSSSKVP-EWPDYIEIKDEEQIQGLRRACQLARHILLLTGNSLKVGMTTDEIDFIVHQEAIRHNGYPSPLHYGGFPKSVCTSVNNVVCHGIPDSRPLQDGDIINIDVTVYLEGYHGDTSETFLIGSVNDQGRKLVDVARQCRDQAIAACGPGQPLCVIGNIISNIANSNGFRVCPYFIGHGIGEYFHGHPEIWHHANDNDLKMEEGMSFTIEPILMEGTSGFRILSDKWTAVSVDDKRSAQFEHTVVITSDGVEILTKLPEED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKV9-1", "uniprot_id": "Q9VKV9_DROME", "id": "Q9VKV9-1", "name": "Methionine aminopeptidase", "aln": "---------MRRIG---------LLNSLMRQKTTARN-LFQFGKVKGDTGKYEQIVSTGQVSPERFVPEEIKKPAYYFKNMPPGNTLGSPEIKSQVQIDAMRLSGRLAARILRECGKLATVGTTTDQIDAFAHERILESKAYPSPLRYAGFPKSICTSINNIACHGIPDDRQLADGDIINIDVTVFLNGYHGDCSETFRVGNVDERGGFLVEATKSCLDQCISLCGPGVEFNEIGKFIDRYCDEHDLASIAAFIGHGIGSYFHGPPEILHYYNEIPGKMQPGMTFTIEPILSLGGAEIAVLQDGWTAISLDGARSAQFEHTILITETGTEILTRDQ---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * * . . : : . . ..:* .. * . **:.*::* * .. * : . *:*.: **:.:: : :** ::* *: .*. **::** :.* . : ..***** *. ****:***:**: ******.* * ***********: :***** **** :*.*:: * **:.:: * *:.*: * .* : **: *.. .:.: . *:*****.**** *** *: *: *: *:******: * . : :*.* **.:*:*. ********::** *.:***: ", "identical_positions": 125, "similar_positions": 91, "identity": "36.87%" }, { "cls_id": "homologset.agr.HGNC:3259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70541-1", "uniprot_id": "EI2BG_RAT", "id": "P70541-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKLKPDIVCIPDEADMGTADSLRHIYPKLKTDVLVLGCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESTEPVPGQKGKKKTVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFQTGLVDAHLYCLKKYVVDFLMENKSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKEPKSLDIYSFIKKDNTLTLAPYDACWNAFRRDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHPSAQIANKHLIGADSLIGSDTQVGEKSSIKRSVIGSSCVIRDRVTVTNCLLMNSVTVEEGSSIHGSVICNNAVVEAGAEIRDCLIGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AUN2-1", "uniprot_id": "B1AUN2_MOUSE", "id": "B1AUN2-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKMKLDIVCIPDEADMGTADSLRHIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESIEPVPGQKGKKKPVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFHTGLVDAHLYCLKKYVVDFLMENRSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKELKSLDIYSFIKKDDTLTLAPYDACWNAFRGDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHSSAQIVNKHLIGADSLIGPDTQIGEKSSIKHSVIGSSCVIRDRTSITNCLLMNSVTVEEGSSIHGSVICNNAVIETGAEIKNCLVGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR50-1", "uniprot_id": "EI2BG_HUMAN", "id": "Q9NR50-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALCAEFK-------------------------MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEED--LKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAK----AKRVNEVIVGNDQLMEI----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZA22-1", "uniprot_id": "A1ZA22_DROME", "id": "A1ZA22-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "MTEFQAVVFAAGR-------------------------GTRLPEVLG----------------DAPKCLLPVGPYPLIWYPLNLLQQHNFTEVIVVVLEQEKLEIQSALENTP----------------------LKLRLDYATIPSDGDFGTADSLRYIYDKIKSDFLVVSCDLVSNVSLYPLINKFR-EHDAALAMLLFPSGFESDVVMPGPKSKHK--PERDLIGIHAATQR-----LAFVSAASDCEETLNIQRHLLKNRGRLDVYSRLVDAHVYVLKKWVIDYLRRKENISTFKGEFLPHLIKKQHSKRPPKTVQDTTSEVGVVTKNEDHVLHYVGHTILDQKITQT---SLFNQSLSQ--SPYHGDIVRCYG-------IQAPRDAIGVRVNNTLSFLAINRKLASIWNNLCGEKHPLISPGAVVKSTQT-KEIIAADNAKLSEKTSLNFSVFGPNCIISPKNIVANSLIMSNAIVEEGCNIDNCIIGHRAQVKSGSVLKNCIIGPNYVVEEG----THSQAVHLSNADQFMEIDIQ-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09032-1", "uniprot_id": "EI2BG_YEAST", "id": "P09032-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MSIQAFVFCGKGSNLAPFTQPDFPFQTQNKDSTAATSGDKLNELVNSALDSTVINEFMQHSTRLPKALLPIGNRPMIEYVLDWCDQADFKEISVVAPVDEIELIESGLTSFLSLRKQQFELIYKALSNSNHSHHLQDPKKINFIPSKANSTGESLQKELLPRINGDFVILPCDFVTDIPPQVLVDQFRNRDDNNLAMTIYYKNSLDSSIDKKQQQKQKQQQFFTVYSENEDSERQPILLDVYSQRDVTKTKYLQIRSHLLWNYPNLTVSTKLLNSFIYFCSFELCQLLKLGPQSMSRQASFKDPFTGNQQQQNPPTTDDDEDRNHD-DDDDYKPSATSIQPTYFKKKNDLILDPINCNKSLSKVFRDLSRRSWQHSKPREPIGIFILPNETLFIRANNLNAYMDANRFVLKIKSQTMFTKNIQIQSAAIG------ADAIVDPKCQISAHSNVKMSVLGTQANIGSRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKLSNCYIEGHYVVEPKNNFKGETLANVYLDEDEEDELIYDDSVIAGESEIAEETDSDDRSDEDSDDSEYTDEYEYEDDGLFER", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**.*:. * :: :: . ** ***:* *:* * *: :: .* *: **. : : : : :: . **...: . : : ::: *.::: **:::::. ::: ** * *** : .. . : *:* . . . :* : : * *: :* : .: . : *:::.:* . : : * . : :..: : :* .. .. :: : .. .. * . : . .: : *... :: ** : .: . : .. : : : . ::. ::.:: **:*... * : ::..*:: .. : : :...:* * : . : :* : :* . . *: *: ", "identical_positions": 54, "similar_positions": 154, "identity": "9.22%" }, { "cls_id": "homologset.agr.HGNC:32594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLR6-1", "uniprot_id": "A0A8I6GLR6_RAT", "id": "A0A8I6GLR6-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein", "aln": "-MEAPGSGSGDGGGDPGGDGAHPDARGP-------SSGPCAAARDSERQLRLRLCVLNEILATERDYVGTLRFLQS-----AFLQRIRQNVADSVDKGLTEENVKILFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKVPAARAFLLNCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELSKRTPGKHPDHSAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDALIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMSKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYAPVIKDRDYHLKTYKSVVPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFKDESQYFRFHADEEMEGTSSKNKQLRNDFKLVENILAKRLLIPPQEDDYGFDLEEKNKAVVVKSVQRGSLAEMAGLQAGRKIYSINEDLVFLRPFSEVETILNQSFCSRRPLRLLVATKAKETIKIPDHPEALSFQIRGTAPPCVFAVGRGSEAVAAGLCAGQCILKVNGNSVANDGALEVLEHFQAFRSRREE-ALGLYQWVYHSHEDAQQARASQGAPDEDP-----QEDD---SVLPLLSLGPQLSLHEDSAVVSLTLDNVHLEHGVVYEYVSTAGAKCHVLEKIVEPRGCFRLAAKILEAFAEDDSLFVQNCGRLMAMGSAIITMSHYEFHNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEDHPLCGLDFCPTNCHINFMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMAYTQHCITTMAAPSWKCAPAVDGDSQSQGLIDSIFVSASGALSQQERGLSFLLKQEDREIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSAAP--CDPPLVEETSSSPPASEESEVDRTDHGGIKKVCFKVSEDEQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDETGSGDELPCDIRIPSDKQDKLHGCLEHLFNQVDSIHALLKGPVMSRAFEETRHFPMEHSWQEFKQKEECTVRGRNLIQISIQEDPWNLPSSIRTLVDNIQRYVEDGKNQLLLALLKCTDTELQLRRDAVFCQALVAAVCTFSEQLLAALDYRYNNNGEYEESSRDASRKWLEQVAATGVLLHWQSLLAPATVKEERTMLEDIWVTLSELDNVTFSFKQLD-ENSVANTNVFYHIEGSRQALKVVFYLDGFHFSRLPSRLEGGASLRLHTVLFTKALENVEGPSPPGSQAAEDLQQEINAQSLEKVQQYYRRLRAFYLERSNLPTDATTTAVKIDQLIRPINALDELYRLMKSFVHPKAGAGG-SLGAGLVPVSSELCYRLGACQITMCGTGMQRSTLSVSLEQAAILARSHGLLPKCVMQATDIMRKQGPRVEILAKNLRIKDPMPQGAPRLYRLCQPPVDGDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZK0-1", "uniprot_id": "PREX1_MOUSE", "id": "Q69ZK0-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein", "aln": "-MEAPGSGGGDGGGDPGGDGAHPDARGP-------VSGPCAAARDSERQLRLRLCVLNEILGTERDYVGTLRFLQS-----AFLQRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKVPAVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHTAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTELLLQGNLLKISAGNIQERAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDALIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMSKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYAPVIKDRDYHLKTYKSVVPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFKDESQYFRFHADEEMEGTSSKNKQLRNDFKLVENILAKRLLIPPQEDDYGFDLEEKNKAVVVKSVQRGSLAEMAGLQAGRKIYSINEDLVFLRPFSEVETILNQFFCSRRPLRLLVATKAKETIKVPDHPEALSFQIRGTAPPCVFAVGRGSEAVAAGLCAGQCILKVNGTSVANDGALEVLEHFQAFRNHREE-ALGLYQWVYHSHEDAQLARASQGAPDEDP-----QEDDQPDSALPLLSLGPQLSLHEDSAVVSLTLDNVHLEHGVVYEYMSTAGAKCHVLEKIVEPRGCFRLAAKILEAFAVDDSIFVQNCGRLMAMSSAIVTMSHYEFHNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQASLEPHPLCGLDFCPTNCHVNLMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQG-LNPMAYTQHCITTMAAPSWKCSPAVDEDSQGQGLNDSSYGSASGAPSQQDRGLSFLLKQEDREIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSAAPAPCDPSLVEETSSSPPVSEESEVDRTDHSGIKKVCFKVSEDEQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGSGDELPCDMRIPSDKQDKLHGCLEHLFNQVDSIHALLKGPVMSRAFEETRHFPMKHSWQEFKQKEECTVRGRNLIQISIQEDPWNLPSSIRTLVDNIQQYVEDGKNQLLLALLKCTDTELQLRRDAVFCQALVAAVCTFSEQLLAALDYRYNNNGEYEESSRDASRKWLEQVAATGVLLHWQSLLAPASVKEERTMLEDIWVTLSELDNVTFSFKQLD-ENSVANTNVFYHIEGSRQALKVVFYLDGFHFSRLPSRLEGGASLRLHTVLFTKALESVEGPPPPGNQAAEELQQEINAQSLEKVQQYYRKLRAFYLERSNLPTDAGATAVKIDQLIRPINALDELYRLMKTFVHPKAGAAG-SLGAGLIPVSSELCYRLGACQITMCGTGMQRSTLSVSLEQAAILARSHGLLPKCVMQATDIMRKQGPRVEILAKNLRIKDPMPQGAPRLYQLCQPPVDGDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCU6-1", "uniprot_id": "PREX1_HUMAN", "id": "Q8TCU6-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein", "aln": "-MEAP--SGSEPGGDGAGDCAHPDPRAPGAAAPSSGPGPCAAARESERQLRLRLCVLNEILGTERDYVGTLRFLQS-----AFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMNKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTYKSVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFRDESQYFRFHADEEMEGTSSKNKQLRNDFKLVENILAKRLLILPQEEDYGFDIEEKNKAVVVKSVQRGSLAEVAGLQVGRKIYSINEDLVFLRPFSEVESILNQSFCSRRPLRLLVATKAKEIIKIPDQPDTLCFQIRGAAPPYVYAVGRGSEAMAAGLCAGQCILKVNGSNVMNDGAPEVLEHFQAFRSRREE-ALGLYQWIYHTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPRLSLCEDSPMVTLTVDNVHLEHGVVYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVENCRRLMALSSAIVTMPHFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCPTNCHINLMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMSYTQHCITTMAAPSWKCLPAAEGDPQGQGLHDGSFGPASGTLGQEDRGLSFLLKQEDREIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSGGS--CDASLAEEASSLPLVSEESEMDRSDHGGIKKVCFKVAEEDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGSGDELPCDMRIPSDKQDKLHGCLEHLFNQVDSINALLKGPVMSRAFEETKHFPMNHSLQEFKQKEECTIRGRSLIQISIQEDPWNLPNSIKTLVDNIQRYVEDGKNQLLLALLKCTDTELQLRRDAIFCQALVAAVCTFSKQLLAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHCQSLLSPATVKEERTMLEDIWVTLSELDNVTFSFKQLD-ENYVANTNVFYHIEGSRQALKVIFYLDSYHFSKLPSRLEGGASLRLHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEKVQQYYRKLRAFYLERSNLPTDASTTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAG-SVGAGLIPISSELCYRLGACQMVMCGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIMRKQGPRVEILAKNLRVKDQMPQGAPRLYRLCQPPVDGDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G9V8-1", "uniprot_id": "A0AC58G9V8_DANRE", "id": "A0AC58G9V8-1", "name": "", "aln": "MSHSYEMLGAERLLWGCGQALMADCHAED-----------ASPQGHTRLFINLGSPQQNEPPTYPAYVFCNGCPSSCNPSLAFLQRIRQTAEN--QQCLTQEQVKVLFSNIESILDVHREFLSTLDASLQPEPQAHHSLGHVFLQFKVRFSVYGEYCSNHEKALRLLMELNKIPHIRAFLLHLMLLGGKKSTDVPLEGYLLSPIQRICKYPLLLRELLKRTPKKHSDYPAVEEALQAMKAVCCNINETKRQMEKLEALEILQSHIEGWEGTNLTDICTELLLQGNLLKISAGNIQERVFFLFDNLLVYCKRKSRVSG-KKSTKRTKSINGPQYVFRGRINTEVMEVENVEDGTADYHSNNYTVTNGWKIHNTAKNKWFVCMAKNAEDKQKWLDAILKEREQRESLKLGMERDAYVMIAEKGEKLYHMMMTKNRHLIKDRRRKLTNVPKCFLGNEFVSWLLESGEISKAEEGINLGQALLENGIIHHVSDKHQFKNEQVLYRFRYDDGTYKARSEMEDIISKGVRLYCRLHSLFTPVVKDRDHHLKTFKSVIPASKLVEWLVSQGDSASREDAVTLGVGLCNAGFMHHVLEKSEFKDESQFFRFYADEETEGTSSKSKQLRSDFKLIENILAKSLVIHPEEEDYGFEIEEKNKAIIVKSVSRGSYAEMAGLQPGRKIYSINEDLVFLRPFSEVETMINQSFCIRRSLRLLVATKNKEIVKIPDVHGTLPFVLSGSCPPHIHAVKKGSEAAAAGLQPGQCVLKVNGNNMNQSGYQEVLEHFSGYQPVLEQQDTSCGQWAYRVYEDVEEQMSFRGCENGSD------SEDGCTNGTGSVRRLEQLSISDDGPLVSLNVDNVHVEHGVVYEYVSPAGIKHCVLEKMVEPKGCFNLTAKILKAFVKDDSLFVKSCRQLMALNDKVVTMPQFEFRNICDTKLESIDKRISSYKQFVEELQTKAWPTFKQASTKPHILGCMDFVPTNCHLNLMQVSCPKNTSSAGRAFSIRFGRKNSFFGLDPDQANLNPMSHSVHCVTSMGAPSFSCQSLDEETENGEGNSED-------SRKHEEGGLSFLLKQEDTESQDNYICLYNRLDIAVREMKQYVAQIDVLLSSITGPTQPQG--SEPPSFESGPSTSPIPEETDQDKTEHCGNKRVCFKVNEDDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGSGDELPCDMQIPFDKQDKLHGCLEHLFNQVDSINSLLKGPVMSKACEETKHFHTDHSQPEFRHTDDWTVRWRYVLHKNIQEDPWNLPISIKSLINSLHRFVEDGRSQLLLALLKCTDTKLQLRRDVIFCQSLVGALCALAEQLVTALNLRFNNNGEYEEDSKEVSHKWLEQISTIGVLFNFQSTLSP-HVREERIMLEDTKAALQDLEKVTVLFRPLENECLVPNTSVHYQVEGSRQAIRVTMFLDNCHFSELPTRLQNGGSLKLQSVLFTRGLEKPEGVLSQDFVTMEEFQQRTNALSLEKVKGYYRKLRAFYLEKSNS--DSNSTAMKIDQLLRPLNTLDDLCRLMQTYMNVKASSAGQPSGVSVLLVSSELCNRLGACQITMCATGMQRCTLTVSLEQATILARNHSLMPRCLMQTMDLMRKQGTRVEISAKNLRVMDQMPPLAPRLFRLCLPPSDGDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ..: *: .* :. *:.: * : . :: * ** .* ***:****.. : :: **:*:**:******.**:**::**::*: .*:****::*.**:***:** :*.** *************:****:* ***** *****:*:**:********************:** **** **.*:.**:.******:**.**************** **********:*******:*****.************.*****************:* ************. *:*************************.***********************.**:*******:::********************************.*: :*********:.***********:**** *****:***:**************************:***************:***:*************::**:****:****:***:*.****:**::***. :**:**:******* ************:****:***:**** ******.****.****:****** *:* *:*:****::******::****.*** **:**** *********************:::** ** **.******** ** :*:** :* * : *:.** :.** :**** **** .***:*****..: :.* ******..:: *: . ** *: :**.: : : . . .:* . : :**: :*..:*:*.:****:********:*.** : ****:***:*** *:****:**. :**:**:.* :***:.. ::**.::**:**********.:**:.*::*. :*:::. *.****. : * * :** *****:*:*:** **.*.*.**:******** *::****:*. ****::: **:*:*.***:.* . : :.:* :. : ::: ********** * ** *: *:.:**:*::******:**: ***:** **. .:.. *. .* . .**:: *:::* * *:***** *::****************************************** *********::** ********************::********:* ***:** .** **::.:: *:* * ::: .********* **::*::.::::****:.************:******.:***:**.*:*::::**::**. *:********.*::.*:*****::: ***:: ** *:* *:*** **** .:*.:*::**. *: *: * *.**.*.*::******::* ::**. ***.**:**:.*.**:*::.***: **. ** . . : *::** ** *****: ***:*******:** *: :**:*****:**:*:**:* ***::::: *..:.* . *..:: :***** ******:.**.*****.**:******:****.*.*:*:*:**: *:*****.**** *****: * ** ****::** ** ****", "identical_positions": 1039, "similar_positions": 382, "identity": "62.14%" }, { "cls_id": "homologset.agr.HGNC:326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D517-1", "uniprot_id": "PLCC_MOUSE", "id": "Q9D517-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "aln": "------------MGLLAYLKTQFVVHLLIGFVFVVSGLIINFTQLCTLALW-PISKHLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTD-QATVD-------------HFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLADYP------------------EYMW---------------FLLYCEGTRFTETKHRISMEVAA--SKGLPPLKYHLLPRTKGFTTAVQCLRGTVAAIYDVTLNFRGNK---------NPSLLGILYGKKYEADMCVRRFPLEDIPA-DETSAAQWLHKLYQEKDALQEMYKQKGVFP---GEQFKPAR----RPWTLLNFLCWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V648-1", "uniprot_id": "G3V648_RAT", "id": "G3V648-1", "name": "", "aln": "------------MGLLAYLKTQFVVHLLIGFVFVVSGLIINFTQLCTLALW-PISKNLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTD-QATVN-------------HFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLANYP------------------EYMW---------------FLLYCEGTRFTETKHRVSMEVAA--SKGLPPLKYHLLPRTKGFTTAVQCLRGTVAAIYDVTLNFRGNK---------NPSLLGILYGKKYEADMCVRRFPLEDIPA-DETGAAQWLHKLYQEKDALQEMYKQSGVFP---GEQIKPAR----RPWTLLNFLCWATFLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRZ7-1", "uniprot_id": "PLCC_HUMAN", "id": "Q9NRZ7-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "aln": "------------MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALW-PVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTD-QATVE-------------RFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYP------------------EYMW---------------FLLYCEGTRFTETKHRVSMEVAA--AKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNK---------NPSLLGILYGKKYEADMCVRRFPLEDIPL-DEKEAAQWLHKLYQEKDALQEIYNQKGMFP---GEQFKPAR----RPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV49-1", "uniprot_id": "Q9VV49_DROME", "id": "Q9VV49-1", "name": "", "aln": "------------MSHLRGLG-----RLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVYIDPQDEQK-------------FFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAEFIFLDRNFEKDKVVIKTQLKEVFSYP------------------DPVW---------------LLLNAEGTRFTPAKHELSVKFAE--ERGLPLLKHHLIPRTKGFTTSLPTMRGICPAIYDINLAFKKNAEP-------KPTMLSQLNGEPVEPYMYIRRVPLDVVPD-DEKEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKPRLSTLLNFLGWATFAVLCILHYLVTSLVAGNWFGFITVLSILGGFYSLMEYAVNASKISKASAYGAAAAKK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38226-1", "uniprot_id": "CST26_YEAST", "id": "P38226-1", "name": "2-acyl-1-lysophosphatidylinositol acyltransferase", "aln": "MLHQK------IAHKVRKVVVPGIS----LLIFFQGCLILLFLQLTYKTLYCRNDIRKQIGLNK-TKRLFIVLVSSILHVVAPSAVRITTENSSVPKGTFFLDLKKKRILSHLKSNSVAICNHQIYTDWIFLWWLAYTSNLGANVFIILKKSLASIPILGFGMRNYNFIFMSRKWAQDKITLSNSLAGLDSNARGAGSLAGKSPERITEEGESIWNPEVIDPKQIHWPYNLILFPEGTNLSADTRQKSAKYA--AKIGKKPFKNVLLPHSTGLRYSLQKLKPSIESLYDITIGYSGVKQEEYGELIYGLKSIFLEGKYPKLVDIHIRAFDVKDIPLEDENEFSEWLYKIWSEKDALMERYYSTGSFV------------------------SDPE-TNHSVTDSFKINRIELTEVLILPTLTII-WLVYKLYCFIF-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12185-1", "uniprot_id": "YD018_YEAST", "id": "Q12185-1", "name": "Uncharacterized acyltransferase YDR018C", "aln": "MKHSQKYRRYGIYEKTGNPFIKGLQRLLIACLFISGSLSIVVFQICLQVLLPWSKIRFQNGINQ-SKKAFIVLLCMILNMVAPSSLNVTFETSRPLK-----NSSNAKPCFRFKDRAIIIANHQMYADWIYLWWLSFVSNLGGNVYIILKKALQYIPLLGFGMRNFKFIFLSRNWQKDEKALTNSLVSMDLNARCKGPLTN-YKSCYSKTNESIA------------AYNLIMFPEGTNLSLKTREKSEAFCQRAHLDHVQLRHLLLPHSKGLKFAVEKLAPSLDAIYDVTIGYSPALRTEYVGTKFTLKKIFLMGVYPEKVDFYIREFRVNEIPLQDDEVFFNWLLGVWKEKDQLLEDYYNTGQFK------------------------SNAKNDNQSIVVTTQTTGFQH-ETLTPRILSYYGFFAFLILVFVMKKNH---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : : . *: * . . : : : : . : : : : . . *.. : : ** *:: * : . .. *: * :*::*: :::* .*:: :*. .: * : . : : ::: ***.:: .:. * . . :: *:*::.*: :: : ::**:.: : . : : :* . :. :* *: *: .: *** : : : ..* * . : * : : ", "identical_positions": 35, "similar_positions": 95, "identity": "7.69%" }, { "cls_id": "homologset.agr.HGNC:3260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63186-1", "uniprot_id": "EI2BD_RAT", "id": "Q63186-1", "name": "Translation initiation factor eIF2B subunit delta", "aln": "MAA----VAVAVR-------------------EESRSEMKTELSPRPGAAGR---------ELTQEEKLQLRKEKKQQKKKRKE--------EKGADQEIGSAVS------------AAQ-RQD-PVRELQGTG---SQLGGTTGEKLPAG-RSKAELRAERRAKQEAERALK--------------QARKGEQGGPSPQACP-STAGEATSGVKRVPEHTQADDPTLLRRLLRKPDRQQ--------------VPTRKDYGSKVSLFSHLPQYSRQSSL----------------TQYMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLHALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFFNKEVTGMSSSKREEEAKSELKEAIDRYVQEKIVLASQAISRFASKKISDGDVILVYGCS-SLVSRILQEAWVEGRRFRVVVVDSRPRLEGRHMLHCLVRAGVPTSYLLIPAASYVL-PEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGD-----------------------------------------------------------QVTLANWQNNSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61749-1", "uniprot_id": "EI2BD_MOUSE", "id": "Q61749-1", "name": "Translation initiation factor eIF2B subunit delta", "aln": "MAA----VAVAVR-------------------EESRSEMKTELSPRPGAAGR---------ELTQEEKLQLRKEKKQQKKKRKE--------EKGADQEIGSAVS------------AAQ-RQD-PIRELPGPG---SQLGGTAGEKLPAG-RSKAELRAERRAKQEAERALK--------------QARKGEQGGVPPQACP-STAGETTSGVKRVPEHTPADDPTLLRRLLRKPDRQQ--------------VPTRKDYGSKVSLFSHLPQYSRQSSL----------------TQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCIALLHALQQVIQDYTTPPSEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFLTKEVTGMSSSKREEEAKSELREALDRYVQEKIVLAAQAISRFASTKISDGDVILVYGCS-SLVSRILQEARVEGRRFRVVVVDSRPRLEGRHMLHSLVRAGVPTSYLLIPAASYVL-PEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGD-----------------------------------------------------------QVALANWQSHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI10-1", "uniprot_id": "EI2BD_HUMAN", "id": "Q9UI10-1", "name": "Translation initiation factor eIF2B subunit delta", "aln": "MAA----VAVAVR-------------------EDSGSGMKAELPPGPGAVGR---------EMTKEEKLQLRKEKKQQKKKRKE--------EKGAEPETGSAVS------------AAQ-CQVGPTRELPESG---IQLG-TPREKVPAG-RSKAELRAERRAKQEAERALK--------------QARKGEQGGPPPKASP-STAGETPSGVKRLPEYPQVDD-LLLRRLVKKPERQQ--------------VPTRKDYGSKVSLFSHLPQYSRQNSL----------------TQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCS-SLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVL-PEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGE-----------------------------------------------------------HVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7A1-1", "uniprot_id": "A0A8M2B7A1_DANRE", "id": "A0A8M2B7A1-1", "name": "Translation initiation factor eIF2B subunit delta", "aln": "MADSDGRQVDSIN-------------------HATGEEGKLQDIVKAKSEGK---------ELTKEEKQRLRKEKKQHKKNKKDDNKGPPEKEKEKEKEKASAPP------------PSKPVTQSPAHKAAAPAPVTASASETPAAAEKPA-KTKAELRAERRARQDSERASK--------------QGKK-EGGQQSTSSKPKASPNELQPVVKRLPEHVQVDDPAALKKLAKKLERQQKSGQGCGLNITGVQVPLRSDYGYKVSLFSHLHQYSRKNPP----------------TQQISIPATVIHPSIVRLGLQYSQGIIAGSNARSVALLHAFKQVIQDYSTPPNEELSRDLVNKLSPYISFLSQCRPLSASMGNAIKYIKKEISNIPNQCKEEEAKGKLQACIDSYINEKIILASEAISKYAIEKISNGDVILVYGCS-SLVNHILCEAFEKQRQFRVIVVDSRPRLEGREALRRLVKKGIRCTYVLISALSYIL-PEVSKVFLGAHALLANGYVMSRVGTSQIALVAKAYNVPVLVCCETYKFCERVQTDSFVSNELDDPDDLIVTRNG-----------------------------------------------------------KTHLENWQTVKSLGLLNLVYDVTPPDFVDLVITDLGMIPCTSVPVVLRVKNVDQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1Q8-1", "uniprot_id": "Q9W1Q8_DROME", "id": "Q9W1Q8-1", "name": "Translation initiation factor eIF2B subunit delta", "aln": "MVLTSEQVPQTLKSKHKKQRQRNRPRNKRNRLEDSHSTTQETSAIDATSAMPGNAVDPLATEKTRDQIMAEREAKKLAKQAKKQKTAPTPTAATPAVLTTPSAPATKIITEVEQTTITTKLTTTTTTKVQDAVASKTTQPAAVNGKDAEAGEKTREQIKAEREAKKAAKKAGKGGGAKVEGIAQQLADLKVAEKAPVAASAAPSTTEADQEKKKPALSKAERRAIQEAQRAAKAQVQTKKAQHAAKAPPSAAPKGPNRKSVSPTTAATSSSPVKCPASTPNVDCRVKLFNHLVCAKEDSQFINDPLVHPSIARLGVQYAKRTVVGSNARCIAFLHALRQVVHDFETPAKKEFGRSLDAAVKHHVDHLHKCRPLAVSVSNAYKQFKNQLTQLPADVPETESKELLVHFIDTYIENQIGKAAQAISGFLQEKITDGDVLLTFACS-SLIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCTYVLINAVGYVM-AEATKVLLGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQTDAIVYNELSDPN--QLVRGD-----------------------------------------------------------KCQLSNWAAKGKLLPLNLSYDITPPELVSAVVTEVAILPCTSVPVILRIKPDIGY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12754-1", "uniprot_id": "EI2BD_YEAST", "id": "P12754-1", "name": "Translation initiation factor eIF2B subunit delta", "aln": "MSESEAKSRSATPPSKAKQATPTTTAAANGEKKLTNKELKELKKQEKAAKRAAMKQANGISIEQQQQQAQMKKEKKQLQREQQQKREQKQKNANKKKQNERNVKK------------STLFGHLETTEERRATILALTSAVSSPKTSRITAAGLMVPVVASALSGSNVLTASS-------------LMPVGPNASSTVSASAPASTTTTLPASSAALSAGTSSASTNTPTAIQQEIASSNASDVAKTLASISLEAGEFNVIPGISSVIPTVLEQSFDNSS------------LISSVKELLLNKDLIHPSILLLTSHLAHYKIVGSIPRCIAMLEVFQIVIKDYQTPKGTTLSRNLTSYLSHQIDLLKKARPLSVTMGNAIRWLKQEISLIDPSTPDKAAKKDLCEKIGQFAKEKIELADQLIIDNASTQIEESTTIVTYGSSKVLTELLLHNAISLKKNIKVIVVDSRPLFEGRKMAETLRNAGVNVMYALITSLDTIFNMDVDYVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQLDSVTFNELADPNDLVNIDYENPVERRGNKGALLNQFIKERKFEKKKLAMENKPKGNKIGGKKGSEGESKDASNEEDSNSKNILDGWQELPSLNIVNILYDLTPPEYIKKVITEFGALPPSSVPVILREYKGSA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : . : : ::: :: ** :: ::: . .. .: . . . .. : *. : . * . : . . : * :: :. : .: . : . . .. . : ::**:: * : :: : ** .*.:*:*..:: *::*: ** :.*.* :. :. * :.**::.:: ** : :.:::: : . : :* * :. : :::* * : * :* :. .::.:..* * . : :* ::*:****** **:. . * *: * ** : . :: :. *:****::*:** : :*.**: :*: *. *:*******: **.:*.* *:.. *** **: : * .* .* :*: **:***: :. *:*:.. :* :****:** ", "identical_positions": 97, "similar_positions": 163, "identity": "14.08%" }, { "cls_id": "homologset.agr.HGNC:3261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64350-1", "uniprot_id": "EI2BE_RAT", "id": "Q64350-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "-MAATAAVPSAVGGRANKR---GGG-SGGGGTQGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQK--SKWCHPTSLNVVRIITSDLYRSLGDVLRDVDAKALVRSDFLLIYGDVVSNINISKALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVLAVDSTTNRILHFQKTQGLR---HFSFPLG-LFQGSLDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTR-DDFVRGLLVNEEILGNQIHLHVT-SREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSSTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVVGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVILKPHCVLTSQVVVGPDIILPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGPEGQGYLWKAEDVDEKEDEELRQSLWGLMINMEEESETESERSVDPEELDSRAGSPQLDDIR-------------VFQNEVLGTLQRGREENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQVDGVLDPNRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVP--SLAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNQQLQRFIQWLREAEEESSDDD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHW4-1", "uniprot_id": "EI2BE_MOUSE", "id": "Q8CHW4-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "-MAATAAVPGAAAGRASKR---GGGGSGGGGTQGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQK--SKWCHPTSPNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDVISNINICRALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVMAVDSATNRVLHFQKTQGLR---RFSFPLS-LFQGSGDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTR-DDFVRGILMNEEVLGNQIHLHVT-TREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSTTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVKLKPYCVLTSQVVVGPDITLPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGLEGQGYLWKAEGVNSKEDEELRQSLWGLMIKTEEESETESEGSVDPEELDSRAGSPQLDDIR-------------VFQNEVLGTLQRGREENISCENLVLEINSLKHAYNISLKEVMQVLTLVVLEFPLQQVDGLLDPNRYCALLLPLLKAWSPVLRNYIKRAADHLEALAAIEDFFLEHETLVT--SMAKVLMAFYQLEILAEETILSWFSQRDTTDEGQQLRKNQQLQRFIQWLREAEEESSEDD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13144-1", "uniprot_id": "EI2BE_HUMAN", "id": "Q13144-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLK--SKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLR---RFAFPLS-LFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTR-DDFVRGLLVNEEILGNQIHMHVT-AKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIK-------------VFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGI--SMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W541-1", "uniprot_id": "Q9W541_DROME", "id": "Q9W541-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "----------------------------------MAQFEKEIVQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLYRSSIREHIRAGIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGADTVTNADLRPVLEQHKRQAKFDKGT-AATLVFKECANNVRT---GNEVLIAVDRRNDRLHYHQRLRMHHKENRYQLPLD-VFLGN-SCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQTR-DDFVRGLLINEELLDSRIYVALLPAAQYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGLYK-LQQEYVFHKDNIYKSPEAHVSKVALLQN-VVIEAGSHVDSGSVISDSVIGANCRIGKNCRLTNAFLMADVTVMDNCRLEHCVVGEGAIINEDCDVSAGCVLGAKSVLPAKKTLAK-TLITRTPSRRRSD------------DEVVVELKSIGPHAYIVSDLTTGDPEDSECEDLLPQQPLSIPKMGDLLAPLDEISYCSDFSEDDED-ASRAVTPLPDDTN-------------IFLGEVIDSLTRGFREKSNPDFLVLEINSSRYAYNMSLKEVN--FNVVKAVFGMQSIVEPANDN-VLVAINAAFKQLGPVVSNYIKSEDSMMDCLKALEDVYEENHLVRG--KISQIVHYLYDKDFVSESAIQAWYAQLDEEEHAHLRQSLAKLVAWLDQSSEEDDDEEDDD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32501-1", "uniprot_id": "EI2BE_YEAST", "id": "P32501-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "----------MAGKKGQKK------SGLGNHGKNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGVHEVFLICSSHANQINDYIEN--SKWNLPWSPFKITTIMSPEARCTGDVMRDLDNRGIITGDFILVSGDVLTNIDFSKMLEFHKKMHLQDKDHISTMCLSKAS--TYPKTRTIEPAAFVLDKSTSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTSHVPLIFQENFDYQSLRTDFVKGVIS-SDILGKHIYAYLT--DEYAVRVESWQTYDTISQDFLGRWCYPLVLDSNIQD--DQTYSYESRHIYKEKDVVLAQSCKIGKCTAIGSGTKIGEGTKIENSVIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKIDDNMDLDRNTKISASPLKNAGSR----MYDNESNEQFDQDLDDQTLAVSIVGDKGVGYIYESEVSDDEDSSTEACKEINTLSNQLDELYLSDDSISSATKKTKKRRTMSVNSIYTDREEIDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVTYHEVR--IATITALLRRVYHFIATQTLGPKDAVVKVFNQWGLLFKRQAFDEEEYIDLMNIIMEKIVEQSFDKPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLT--VKWVEWLQNADEESSSEEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:::*. .* *:: . ****.** :::*:* * :**.*.*: . .*.::: :. : * . *. **.:**:* :.:: ..*:*: .*.::* :: ** *: :*. : * . . . : . ..:* ..* :.* : : :. : .. . . :: :*:* :* * :. : :* :***:*: ***:*:: .::*..:*: : :*. :*.. *. :. *.: ** **:. : .: . * . :**: :. :.: . : : . : :*: :... * :**** .*:**.* : :::: . : .. :.:.:: . * : . :. .:: : : . * . : *: * . :: .:. *. * .: : .. . :* .: . . .: : :. * * : :: *. .:: . : :**:*: : : *:: :** : : : : : :: . :. . . :: : : : *: : . : :*: ::: *..* *: : . . . :. ::: : :::...:: ", "identical_positions": 96, "similar_positions": 249, "identity": "12.89%" }, { "cls_id": "homologset.agr.HGNC:3262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y871-1", "uniprot_id": "A0A8I5Y871_RAT", "id": "A0A8I5Y871-1", "name": "Protein argonaute-1", "aln": "LPNSRRWPDSVLTGFFVFTAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLERDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJG1-1", "uniprot_id": "AGO1_MOUSE", "id": "Q8CJG1-1", "name": "Protein argonaute-1", "aln": "-------MEAGPSG----AAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL18-1", "uniprot_id": "AGO1_HUMAN", "id": "Q9UL18-1", "name": "Protein argonaute-1", "aln": "-------MEAGPSG----AAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WG39-1", "uniprot_id": "X1WG39_DANRE", "id": "X1WG39-1", "name": "Protein argonaute-1", "aln": "-------MEAGPSG---AVPVGPYPPPLQQVFQAPRRPGMGTVGKPIKLLANYFEVEIPKMDVFHYEVDIKPDKCPRRVNREVVEYMVQHFKPQLFGDRKPVYDGKKNIYTVLALPIGSEKVDFEVTIPGEGKDRIFKVSIRWLAKVSWRLLQETLVSGRLQVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKTLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNANFNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKSERIGKSGNIPAGTTVDTSITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHVSGQSNGRDPQALAKAVQIHHDSLRTMYFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* ...*.* **************:****************:***:**:******************************:***************** *****.*:********************:*** ****:*:*:****:: ***********************************************************************************************.*****************************************************************************************************************************************.:*******************************************************************************************************************************************************************************************************************************************************************************************************************:************************.*****************.******************************************************************************************:*****************:*:*:*******", "identical_positions": 820, "similar_positions": 30, "identity": "94.47%" }, { "cls_id": "homologset.agr.HGNC:3263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ81-1", "uniprot_id": "AGO2_RAT", "id": "Q9QZ81-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKEYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJG0-1", "uniprot_id": "AGO2_MOUSE", "id": "Q8CJG0-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKV8-1", "uniprot_id": "AGO2_HUMAN", "id": "Q9UKV8-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPALAPPAPPP-PIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AKD0-1", "uniprot_id": "A0A8M3AKD0_DANRE", "id": "A0A8M3AKD0-1", "name": "Protein argonaute-2", "aln": "MYPIGAAGATELFQGRPSSGSDVSAPASPP-APQEYVFKPPQRPDFGTMGRTIKLQANFFEMEIPKLEVYHYEIDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVYDGRKNLYTAMPLPIGRDKVELEVTIPGEGKDRSFKVAIKWMSCVSLQALHEALSGRLPNIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDDMTEVNGRVLQAPSILYGGRVRISSAQLSIWLNPCLIWSCLWLFQNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLATMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPFEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* :*. ::.**... . *.**** ****** *************:***:::****:**********************************:************************:******* ***:***:*********:*******.:*****************************.*************************************************:*****************************************************************.***:**********::************************************************************:*********.***********:**:*:**:*.*****.******* :*****************************************: **:**:*********************************:*** ** ***********************************:****:****************************** *************************************.*************:******:*********************:****:*****:***:***************:*******:************ *:*********************** ****************************:*:*****:*********************************************************:********:***********", "identical_positions": 785, "similar_positions": 61, "identity": "87.32%" }, { "cls_id": "homologset.agr.HGNC:3265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68101-1", "uniprot_id": "IF2A_RAT", "id": "P68101-1", "name": "Eukaryotic translation initiation factor 2 subunit 1", "aln": "MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEVDGDDDAEEMEAKAED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWX6-1", "uniprot_id": "IF2A_MOUSE", "id": "Q6ZWX6-1", "name": "Eukaryotic translation initiation factor 2 subunit 1", "aln": "MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEVDGDDDAEEMEAKAED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05198-1", "uniprot_id": "IF2A_HUMAN", "id": "P05198-1", "name": "Eukaryotic translation initiation factor 2 subunit 1", "aln": "MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVDGDDDAEEMEAKAED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20459-1", "uniprot_id": "IF2A_YEAST", "id": "P20459-1", "name": "Eukaryotic translation initiation factor 2 subunit alpha", "aln": "MSTSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIP----LEELYKTIAWPLSRKFG----HAYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQALLESKELDN-RSDSEDDEDESDDE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ****::*:**::*:*****:.********.****:*******************:****:*:*: .**:*****************.*: ****:*: *****:****: ** :: . **.*:: ** :. *: **:*** :: * :: :.:: .:* : * * *.:************:**:*:.******:*:**::. : *** * :*::*:*.* **:** :*:: :*:. *..*: *.* * : ** *: * **.** *:::** :* * :* . *.:** :* : : ", "identical_positions": 164, "similar_positions": 86, "identity": "51.9%" }, { "cls_id": "homologset.agr.HGNC:3266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L45-1", "uniprot_id": "IF2B_MOUSE", "id": "Q99L45-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MS---GDEMIFDPTMSKKKKKKKKPFMLDEEGDAQTEETQPSETKEVEPEPTEEKDVDADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIE--SDAQEPAEPEDDLDIMLGNKKKKKKNVKFPEEDEILEKDEA-LEDEDSKKDDGISFSSQT--AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEK-RKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDT--RLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20042-1", "uniprot_id": "IF2B_HUMAN", "id": "P20042-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MS---GDEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIE--SDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEA-LEDEDNKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEK-RKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDT--RLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41375-1", "uniprot_id": "IF2B_DROME", "id": "P41375-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MD---AEDG-FDPTLLKKKKKKKTTFDLD------AALGLEDDTKKEDPQ----------DEASAEGGAAAEEDNLDLESFGKKKKKKKKPFNMDEIEAAIPSFGGDDVAASEEPEEEEINLDMDFSMAKKKKKSKKKELDELFADQADD-DKSEDKENDEDNSS------TWFGSDRDYTYDELLKRVFEIILDKNPDMAAGRK-PKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDT--RLFFLQCESCGSRCSVASIKSGFQAVTGKRAAIRAKTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09064-1", "uniprot_id": "IF2B_YEAST", "id": "P09064-1", "name": "Eukaryotic translation initiation factor 2 subunit beta", "aln": "MSSDLAAELGFDPALKKKKKTKK---------------VIPDDF-----------------DAAVNGKENGSGDDL-FAGLKKKKKKSKSVSADAEAEK--------------EPTDDIAEALGELSLKKKKKKTKDSSVDAFEKELAKAGLDNVDAESKEGTPSAN----SSIQQEVGLPYSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRRRM-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . : ***:: ****.** .: : : : . *:* : . *****.*. * * ** : : :. *****. . : : . .. * :..:. . : .: . .*.***.*.*:*: :**::..... ** : ** :* * *** * *: **.: *** *:**: :*:********:**:::*:***:** **:******** *****:**:* :* *::: **:*: *::* * **:***:****..*** : ", "identical_positions": 111, "similar_positions": 83, "identity": "32.46%" }, { "cls_id": "homologset.agr.HGNC:32669", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVM4-1", "uniprot_id": "LIN41_RAT", "id": "D3ZVM4-1", "name": "E3 ubiquitin-protein ligase TRIM71", "aln": "MASFPETDFQICLLCKEMCGSPAPLSSSSSASSSSSQTSTSSAGGGG-PGAAARRLHVLPCLHAFCRPCLEAHRLPAPGGAGPAEALKLRCPVCDQKVVLAEAAGMDALPSSAFLLSNLLDAVVATADEPPPKNGRAGGGPGGAGGHSNHRHHAHHPAQRAAAPAP------QPPP-------GPAASPGSLLLRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIE----RGPPGPAAASAAQQLGLGPPFAGAPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTLGRHGGHSFAYLQDALQDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEERECELLWKVEKIRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRALDILLARDRMLAQVQELKTIRGLLQPQE--DDRVMFTPPDQALYLALKSFG---FVSSGAFAPLTKAAGDG--IKRALQGKVASFTVMG--YDHNGEPRLSGGDLMSVVVLGPDGNLFGAEVSDQ----QNGTYVVS---YRPQLEGEHLVSVTLYNQHIENSPFKVVVKSGRSYVG------------------IGLPVLSFGSEGDGEGKLCRPWGVSVDKEGYIIVADRSNNRIQVFKPCGSFHHKFGTLGSRPGQFDRPAGVACDASRRIVVADKDNHRIQIFTFEGQFLLKFGEKGTKNGQFNYPWDVAVNSEGKILVSDTRNHRIQLFGPDGVFLNKYGFEG-SLWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHPDCQSAR-FLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFEANGSFLCKFGAQGSG-------FGQMDRPSGIAVTPEG-LIVVVDFGNNR----------ILIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1PSW8-1", "uniprot_id": "LIN41_MOUSE", "id": "Q1PSW8-1", "name": "E3 ubiquitin-protein ligase TRIM71", "aln": "MASFPETDFQICLLCKEMCGSPAPLSSNSSASSSSSQTSTSSAGGGG-PGAAARRLHVLPCLHAFCRPCLEAHRLPAPGGAGPAEALKLRCPVCDQKVVLAEAAGMDALPSSAFLLSNLLDAVVATAEEPPPKNGRAGGGPGGAGGHSNHRHHAHHPAQRAAAPAP------QPPP-------GPAASPGSLLMRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIE----RGPPGPAAASAAQQLGLGPPFAGAPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTLGRHGGHSFAYLQDALQDSRALTIQLLADAQQGRQALQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEDRECELLWKVEKIRQVKAKSLFLQVEKLRQSLSKLESTISAVQQVLEEGRALDILLARDRMLAQVQELKTIRGLLQPQE--DDRIMFTPPDQALYLALKSIG---FVSSGAFAPLTKATGDG--IKRALQGKVASFTVMG--YDHDGEPRHSGGDLMSVVVLGPDGNLFGAEVSDQ----QNGTYIVS---YRPQLEGEHLVSVTLYNQHIENSPFKVVVKSGRSYVG------------------IGLPGLSFGSEGDGEGKLCRPWGVSVDKEGFIIVADRSNNRIQVFKPCGSFHHKFGTLGSRPGQFDRPAGVACDASRRIIVADKDNHRIQIFTFEGQFLLKFGEKGTKNGQFNYPWDVAVNSEGKILVSDTRNHRIQLFGPDGVFLNKYGFEG-SLWKHFDSPRGVAFNNEGHLVVTDFNNHRLLVIHPDCQSAR-FLGSEGSGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFEANGSFLCKFGAQGSG-------FGQMDRPSGIAVTPDG-LIVVVDFGNNR----------ILIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2Q1W2-1", "uniprot_id": "LIN41_HUMAN", "id": "Q2Q1W2-1", "name": "E3 ubiquitin-protein ligase TRIM71", "aln": "MASFPETDFQICLLCKEMCGSPAPLSSNSSASSSSSQTSTSSGGGGGGPGAAARRLHVLPCLHAFCRPCLEAHRLPAAGGGAAGEPLKLRCPVCDQKVVLAEAAGMDALPSSAFLLSNLLDAVVATADEPPPKNGRAG-APAGAGGHSNHRHHAHHAHPRASASAPPLPQAPQPPAPSRSAPGGPAASPSALLLRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIE----RGPPGPGAAAAAQQLGLGPPFPGPPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTMGRHGGHSFIYLQEALQDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEERECELLWKVEKIRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRALDILLARDRMLAQVQELKTVRSLLQPQE--DDRVMFTPPDQALYLAIKSFG---FVSSGAFAPLTKATGDG--LKRALQGKVASFTVIG--YDHDGEPRLSGGDLMSAVVLGPDGNLFGAEVSDQ----QNGTYVVS---YRPQLEGEHLVSVTLCNQHIENSPFKVVVKSGRSYVG------------------IGLPGLSFGSEGDSDGKLCRPWGVSVDKEGYIIVADRSNNRIQVFKPCGAFHHKFGTLGSRPGQFDRPAGVACDASRRIVVADKDNHRIQIFTFEGQFLLKFGEKGTKNGQFNYPWDVAVNSEGKILVSDTRNHRIQLFGPDGVFLNKYGFEG-ALWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHPDCQSAR-FLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFESNGSFLCKFGAQGSG-------FGQMDRPSGIAITPDG-MIVVVDFGNNR----------ILVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P6Z4-1", "uniprot_id": "A0A8M1P6Z4_DANRE", "id": "A0A8M1P6Z4-1", "name": "E3 ubiquitin-protein ligase TRIM71", "aln": "MASFPDSDLQTCPLCKELCGCSAPISSNSSTSSSSSQTSNSSS------TSSTRRLHVLPCLHAFCRQCLEGQRS-------PGDPLKLRCPTCDQKVSLSES-GVDALPSSNFLFSNLLDVVVSAEEQG--KNGRSS-AVVHHGGLLRPQHLSD-----------------------------------------PQ-CSSCDEGNPATSHCLDCQEYLCDNCVRAHQRVRLTKDHFIEGLLESLHLANRTNNSNTPVSISQSFHN-SFSMLNVFQERMDFCQHHDDAVLRFFCDSCTVPICRECSLGRHAGHSFTYLQDALQDSRALTIQLLADAQQGRQAIQLSIEKAQAIAEQVELKAKVVQSEVKTITLRHKKALEERECELLWKVEKIRQVKAKSLYLQVEKLHQNLTKLDSTIATVTQVLEEGRSIDVLLAREHMLNQLQELKSLRCILQPQE--DDRIMFTPPDQALLIAIKSLG---LISSGAFATASKAHGEG--IKRALQGKPASFTVVG--YDHDGEPRLSGGDSVSVVLMSPDGNLSSAEVSDH----QDGTYTVS---YLPKGEGEHLLSVLICNQHIEGSPFKVMVKSGRSYGG------------------VGLPMASFGGEGDGDGQLCRPWGICVDKEGYVVVADRSNNRVQIFKPCGTFHHKFGTLGSRPGQFDRPAGVACDSQRRIIVADKDNHRIQIFTFDGQFLLKFGEKGTKNGQFNYPWDVAVNFEGKILVSDTRNHRVQLFGPDGTFLNKYGFEG-ALWKHFDSPRGVAFNQEGHLVVTDFNNHRLLVIRPDCQSAR-FLGSEGTGNGQFLRPQGVAVDQEDRIIVADSRNHRIQVFEPNGNFLCKFGTHGNG-------FGQMDRPSGIAVTPDG-VIVAVDFGNNR----------ILMF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4M2-1", "uniprot_id": "WECH_DROME", "id": "Q9V4M2-1", "name": "Protein wech", "aln": "-------------MMELLSNNSVPQQMASSNAPSANNVAHSSTANGS--GGGSVSSNASNSSERLLAGILE------------------SFPAWDLNVGLLPNVGQSSPPRADFFINNFLGGLDTH--------GDFSIGPIGSGARSNPKMSPESSN------------------------------------NSSISCGWCEVS--ASIRCLECNEFMCNDCLREHRNSPLSSNHSIVS-------------LPTPIGASPTGGS---SVNAQTPPSGNFICDIHNEMLRYVCDYCRKLVCQCCTLHEHKEHSYASIQSFMVGSKEKLEGAIESSQVGTRCIKSSIDKALAFIRLIERNCSELSDNIRKAFRQFIIAIEDRERFLLDFVEKLRQRRLAILHDQMAGLKSALAGLSETSDMLSKVADNACNMDQIEIAMKLTNGQRQMEQFAGIYKDLQPKQEVFAFAPPDYSLLQDIRNQGGVILVDDKNLPIVSSSNGIVPSVSSVNAVAAASVGVVGGVAGVVGGVGVSNGLDLAFGMNMPNNPLSVASSSVRRPLLRDNSFRIPSPIMQPRGGSACGMSSGMSSAALDWELNGLRSSPGLHFSAPRTTQAIPGCMDLVKVRNSNALSLSFATEGHEDGQVSRPWGLCVDKMGHVLVSDRRNNRVQVFNPDGSLKFKFGRKGVGNGEFDLPAGICVDVDNRIIVVDKDNHRVQIFTASGVFLLKFGSYGKEYGQFQYPWDVAVNSRRQIVVTDSRNHRIQQFDSEGRFIRQIVFDNHGQTKGIASPRGVCYTPTGNIIVSDFDNHCLYLIDPDINDILSVKGHEGSGFHEFNRPSGLCCDDEGRIIVADSKNQRILVFNQNLDFMWDIEVRPSINPLMPPTLDEKDRTCDVAIMPDGRIVFLIELSPDSKEGSNPYKRFVHVF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.. ..* . ** :.*:.:.: ** ..: :. . . : ** *. * :* * * .: * : *::.*:*. : : * . . *. . : .. . *. *: . *: :**:*:*.:*::*:* *:. *:.:* * :. . . . *: .* . .: :*: ** * :*: *:: .* **: :*. : .*: : .:* * :.:: **::* :. . :* :.. :..::: :. *:*:** ** ***:** : *. *: *:. * *..* : :* ::. :* : :: :::: . : : : :: . *:*** :* ::. * ::.. :. :.: * :. . **. *:* . * *.* :: : *:. * *. * : ::.:: :. *: . :* : . :: . : ..* : . . **. **. :*::.****:.*** *.::*:** ***:*:*:* *:::.*** * *:** ***:. * ..**:*.******:**** .* ******. *.: ***:******** . :*:*:*:****:* *..:* *:.: *:. . * : *****.:. *:::*:**:** * :* ** :. . * **:* :* **.*:. *:*.*******:*:*: :*: * .*: .: .: . :.: **...:*: *:* ::. :::. : : :*", "identical_positions": 214, "similar_positions": 284, "identity": "23.09%" }, { "cls_id": "homologset.agr.HGNC:3267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "C9WPN6-1", "uniprot_id": "IF2H_RAT", "id": "C9WPN6-1", "name": "Eukaryotic translation initiation factor 2 subunit 3, Y-linked", "aln": "-----------MAGG-----------EAGVTLGQPHLSRQDLA-------------------------------------TLDVTKLTPLSHEIISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDSSCPRPECYRSCGSSTPDEFPSDIPGIKGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTIDDE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0N2-1", "uniprot_id": "IF2H_MOUSE", "id": "Q9Z0N2-1", "name": "Eukaryotic translation initiation factor 2 subunit 3, Y-linked", "aln": "-----------MAGG-----------EAGVTLGQPHLSRQDLA-------------------------------------TLDVTKLTPLSREIISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDSSCPRPECYRSCGSSTPDEFPSDIPGTKGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDGEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTIDDE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z0N1-1", "uniprot_id": "IF2G_MOUSE", "id": "Q9Z0N1-1", "name": "Eukaryotic translation initiation factor 2 subunit 3, X-linked", "aln": "-----------MAGG-----------EGGVTLGQPHLSRQDLA-------------------------------------TLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81795-1", "uniprot_id": "IF2G_RAT", "id": "P81795-1", "name": "Eukaryotic translation initiation factor 2 subunit 3, X-linked", "aln": "-----------MAGG-----------EAGVTLGQPHLSRQDLA-------------------------------------TLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41091-1", "uniprot_id": "IF2G_HUMAN", "id": "P41091-1", "name": "Eukaryotic translation initiation factor 2 subunit 3", "aln": "-----------MAGG-----------EAGVTLGQPHLSRQDLT-------------------------------------TLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGW6-1", "uniprot_id": "IF2G_DANRE", "id": "F1QGW6-1", "name": "Eukaryotic translation initiation factor 2 subunit 3", "aln": "-----------MAGD-----------ESGTTLGQPHLYKQDLS-------------------------------------TLDVSKLTPLSQEIISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKVYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVNKIPVPVRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQELEVRPGIVSKDHEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLAKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTITPTVDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24208-1", "uniprot_id": "IF2G_DROME", "id": "Q24208-1", "name": "Eukaryotic translation initiation factor 2 subunit 3", "aln": "-----------MATA-----------EAQIGVNR-NLQKQDLS-------------------------------------NLDVSKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLGYANAKIYKCDNPKCPRPASFVSDASSKDDSLPCTRLNCSGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKQILILQNKIDLIKESQAKEQYEEITKFVQGTVAEGAPIIPISAQLKYNIDVLCEYIVNKIPVPPRDFNAPPRLIVIRSFDVNKPGCEVADLKGGVAGGSILSGVLKVGQEIEVRPGVVTKDSDGNITCRPIFSRIVSLFAEQNELQYAVPGGLIGVGTKIDPTLCRADRLVGQVLGAVGQLPDIYQELEISYYLLRRLLGVRTDGDKKGARVEKLQKNEILLVNIGSLSTGGRISATKGDLAKIVLTTPVCTEKGEKIALSRRVENHWRLIGWGQIFGGKTITPVLDSQVAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32481-1", "uniprot_id": "IF2G_YEAST", "id": "P32481-1", "name": "Eukaryotic translation initiation factor 2 subunit gamma", "aln": "MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQ-AKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : ** . *.:**.*** *:*.*********************:*****:*****:****************:** ::..**.* .: * *.. . . *.::*****************:***.************************************:::*****:**::*..* *: :.* *::**:*:****:**********:.: *:**:.**** *** ***************.*: ************.**:*:*:*:*:***:*:** .*:: *:****.*******:*:*::*.**********:*********:****:** * **:*: ::**.*:********:*:*:*: *:*.**. **:*:***** :**.*: *.*.*:.:: **.*.*** .********:*:*******. * * *: * ", "identical_positions": 304, "similar_positions": 105, "identity": "56.82%" }, { "cls_id": "homologset.agr.HGNC:32670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PP9-1", "uniprot_id": "TRI16_MOUSE", "id": "Q99PP9-1", "name": "Tripartite motif-containing protein 16", "aln": "MAELDLIAPGPLTGVTAHP--------------------LAPLGPDP--------------VSAIPVEKEDADPLSKSGEETQEQGHDPAELGAPGEEDQILCDFCLGASRVRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPAKDQDLRTCPAHHSPLVSFCHTHQQCICQECGEGEHRGDSTVSLDAARRNKEVDLRCMQLDLEQKLKLNENAIARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQADVMVFLEEKEQAALNQVNSIKTHLEHRSLEMEKSKQELERLAAISNTVLFLEEYCKLKK-TEDTASPSIYIGLKDKLSGIRKVITDSTLNLIQLLES-YKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQEDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVELSGGGTYVGLTCKGIDRKGEERNSCISGNSFSWSIHWNGKEFTAWHSDTETPLKVSPFRRLGIYVNFPGGILSFYGVEYDAMTLIHKFDCKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAGSSVEAAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q309B1-1", "uniprot_id": "TR16L_HUMAN", "id": "Q309B1-1", "name": "Tripartite motif-containing protein 16-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELETMAAISNTVQFLEEYCKFKN-TEDITFPSVYIGLKDKLSGIRKVITESTVHLIQLLEN-YKKKLQEFSKEEEYDIRTQVSAIVQRKYWTSKPEPSTREQFLQYVHDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDQKGEERSSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFWRLGVYIDFPGGILSFYGVEYDSMTLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P9M9-1", "uniprot_id": "A0A8M1P9M9_DANRE", "id": "A0A8M1P9M9-1", "name": "", "aln": "MSAMVLTAELPACSMTSEIPKEEKIEENRPKYTEVEDKKIQVNGSPPEKHTEGEKDVKTIEESKIQKDLKEIEVNKESKDPQKDDEDDEEEEEEVLGPDVVTCDSCIDKP-CRAKKSCLTCLVSYCESHLRPHLENAKFQSHRLVDPLRDIERRTCEAHRSPLELYCC--MCCLCPACVTEEHLGHQALPIAEARRNIEKELQDKQTEMLKTMTAAENAINKLQVNTVSIEGSVQEVRAVMEEQFSILQAAVEQVKRDVCELLEAEERQALRQADGIRVHLEQRCAELKKTQSRVQKISKNKHDIHFLQEYSEWKKEAVDVSLPGVYIGLVDRLQAFSHVIVRSTNRMCDNLHSSYTNKLKDTCKNDNVGIKTTVFAVMAAKKNMMLPDPKTRDDFLQYVTPLSLDANTAHVFLRLTEECKKVTNTTPWQHSYPDLPERFQDFKQVLTQESFYLGRHYFEVDMKGEGTHVGLTYKSIDRKGSQSNSCIAGNNFSWCLQWNGRSFSAWHSDVETPLSCPKTTHIGIYVDYSGGLLAFYDVEN-GMTLIHKYQAEFLEPLYPAFWLPKKENVVLLEPGAASPLSSPSPSPDASTK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. * ***.:.: :* :** :*: ** *.:.*:.*** *. *::*::..:: :: .: : **:**.: *: : * : *.:**** *:*..: :**. ** .: : *.. *.:**:: .:::: .*:* * *:: * *:* **::****. :::*.:*** :*** *: :********:*.*****.** .::***:*:*:** *:****:: * **:**** *.**:**.: .***:**.***.::***:.*:**:** ****. ::*:*:::.**:*:**.** .***:**: .:* **:*.****.****.: : . .* ... . ::. ", "identical_positions": 148, "similar_positions": 131, "identity": "24.96%" }, { "cls_id": "homologset.agr.HGNC:32671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPQ4-1", "uniprot_id": "TRI72_RAT", "id": "A0JPQ4-1", "name": "Tripartite motif-containing protein 72", "aln": "MSTAPGLLRQELSCPLCLQLFDAPVTAECGHSFCRACLIRVAGEPADDGTVACPCCQASTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRTLVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKAQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRMFLAALESSLDREAERVRGEAGVALRRELSSLNSYLEQLRQMEKVLEEVADKPQTEFLMKFCLVTSRLQKILSESPPPARLDIQLPVISDDFKFQVWKKMFRALMPELEELTFDPSSAHPSLVVSASGRRVECSEQKAPPAGEDTCQFDKTVAVVAKQLLSQGEHYWEVEVGDKPRWALGVMAADASRRGRLHAVPSQGLWLLGLRDGKILEAHVEAKEPRALRTPERPPARIGLYLSFADGVLTFYDASNTDALTPLFSFHERLPGPVYPMFDVCWHDKGKNSQPLLLVGPDSEQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1XH17-1", "uniprot_id": "TRI72_MOUSE", "id": "Q1XH17-1", "name": "Tripartite motif-containing protein 72", "aln": "MSAAPGLLRQELSCPLCLQLFDAPVTAECGHSFCRACLIRVAGEPAADGTVACPCCQAPTRPQALSTNLQLSRLVEGLAQVPQGHCEEHLDPLSIYCEQDRTLVCGVCASLGSHRGHRLLPAAEAQARLKTQLPQQKMQLQEACMRKEKTVAVLEHQLVEVEETVRQFRGAVGEQLGKMRMFLAALESSLDREAERVRGDAGVALRRELSSLNSYLEQLRQMEKVLEEVADKPQTEFLMKFCLVTSRLQKILSESPPPARLDIQLPVISDDFKFQVWKKMFRALMPALEELTFDPSSAHPSLVVSSSGRRVECSDQKAPPAGEDTRQFDKAVAVVAQQLLSQGEHYWEVEVGDKPRWALGVMAADASRRGRLHAVPSQGLWLLGLRDGKILEAHVEAKEPRALRTPERPPARIGLYLSFADGVLAFYDASNPDVLTPIFSFHERLPGPVYPIFDVCWHDKGKNAQPLLLVGPEQEQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMU5-1", "uniprot_id": "TRI72_HUMAN", "id": "Q6ZMU5-1", "name": "Tripartite motif-containing protein 72", "aln": "MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDREAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPEGAEA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****:***************************** ******* **** ******.************:*****************************:***********************:*********** ***********:******************************:******.***********:*********.******************************:***********:*************:**********:******** ******************:********:*********. ****:*****:* **:*******:***********:**:*.*******************:*****************:*** *:********.****:*****:.*.*.*:*:****** ****:***********:********: :*", "identical_positions": 426, "similar_positions": 40, "identity": "89.31%" }, { "cls_id": "homologset.agr.HGNC:32672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BLX8-1", "uniprot_id": "WDR83_RAT", "id": "Q5BLX8-1", "name": "WD repeat domain-containing protein 83", "aln": "MAFPEPKPRAPELPRKQLKT-LDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRKPEPVQTLDEARDGISSVKVSDHEILAGSVDGRVRRYDLRMGQVTSDYVGSPITCTCFSRDGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQKYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGSLALALPVG--SNVVQSLAYHPADPCLLTAMGGSIQYWREETYEAEGGAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAJ4-1", "uniprot_id": "WDR83_MOUSE", "id": "Q9DAJ4-1", "name": "WD repeat domain-containing protein 83", "aln": "MAFPEPKPRAPELPQKRMKT-LDCSQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRKPEPVQTLDEARDGISSVKVSDHEILAGSVDGRVRRYDLRMGQVSSDYVGSPITCTCFSRDGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQQYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG--SNVVQSLAYHPTEPCLLTAMGGSIQYWREETYEAEGGAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRX9-1", "uniprot_id": "WDR83_HUMAN", "id": "Q9BRX9-1", "name": "WD repeat domain-containing protein 83", "aln": "MAFPEPKPRPPELPQKRLKT-LDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG--SGVVQSLAYHPTEPCLLTAMGGSVQCWREEAYEAEDGAG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DH44-1", "uniprot_id": "WDR83_DANRE", "id": "Q6DH44-1", "name": "WD repeat domain-containing protein 83", "aln": "MAFPQPRPQAPQLPQHLWRT-VDCQQGAVRAVRFNADGNYLLTCGSDKSLKLWSVSRGTLLKTYSGHGYEVLDADGSYDNSQLCSCSSDKTVILWDVASGQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCWDTRSRRMEPIQILDESQDGISSLKVSEHELLTGSVDGRVRRYDLRMGQLQVDYIGSPITCVCFSRDGQCTLSSSLDSTVRLLDKSTGEMLGEYSGHVNKGYKLDCCLTDKDTHVLSCSEDGHVYYWDLVEGSLTLKLPVG--KAVVQSLSFHPTEPRLLTSMEGRVQVWGAEPEDAAENES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJL9-1", "uniprot_id": "Q9VJL9_DROME", "id": "Q9VJL9-1", "name": "WD repeat domain-containing protein 83", "aln": "---------MPEFENFNVKTTIDCKQGAVRAVRYNVDGTYCLSCGSDKKIKLWNPASGLLLKTYGGHADEVTDAAGSCDSSYIVSASLDKSIIYWDVSTGAPVRRLRSHAGGVRCVCFNEDSSIAISGGRDNAVMCWDIRTRRLDPVQVMKEARDCITTVATNENRIYAASLDGCVRTYDIRVGELTCDKIGEPITYLAQTRDEQCLVAGCQDSVVRLLDCETGGLLSEYRGHRGDDYHIECGILSNDAQIVTGSSDGDAFVYDLLDGKVLQRIRISDNGGVVHSLATHPKRQEMLFARRRDMYVFSTDLQIEEEQL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: . :* :** ********:*.**.* *:*****.:***. * **:**.**. ** ** ** *.* : * . **::: ***::* .*::*.*** *. * ***:::: :**. *.:: *** *:*: :*:* :.*::* :::: ..::.: :.*:** ** **:*:*:: * :*.*** . :** ** : .. **.:**** .** :*.** ** .. *:::* : ..*::::: *.**..: :**::* : : :. **:**: ** :* : : : : ", "identical_positions": 116, "similar_positions": 105, "identity": "36.48%" }, { "cls_id": "homologset.agr.HGNC:32686", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NK02-1", "uniprot_id": "TRI75_HUMAN", "id": "A6NK02-1", "name": "Tripartite motif-containing protein 75", "aln": "--------------------------------------------------------------------------MAVAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLD-----LQELFPCPVCRHQCQEGHFRSNTQLGRMIE-----IAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELS-ELSELELLSQIKIFYE--SENESSPSIFSIHLKRDGCSFPPQY---SALQRIIKKFKVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAFPTPLLLEVKARA-IGIFLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYFYVG-----PDSQPLRICTGTVCE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UWZ0-1", "uniprot_id": "TRI75_MOUSE", "id": "Q3UWZ0-1", "name": "Tripartite motif-containing protein 75", "aln": "--------------------------------------------------------------------------MAHVEVLARLQKETKCPICLDDLTDPVTVECGHNFCRSCIKDFWAG-----QQATSSCPVCRHQCQHRNLRSNAQLGNMIE-----TAQLLQGME-NKR-HESSTSCERHNQALTLFCEDDLQLLCDQCVEPESHGRHQVLSITEAASLHRKHLQDYSKLLKWEVKEIQGLMSALNKRTVTLREQAEAQRSQLTSECEKLMRFLDQEERAAFSRLEDEEMRLEKRLLDNIAALEHHGSSLRDLLRHLMLTG-ELSEAKMLSTVKDFYLNCRRQLISPSIFPVQLRRVEYSFPLQY---SALQKVIQHFTDNVTLDLKTAHPNLLISKDRTCVTFTKKRQRIPGSSS-FTKSPVVLGIPHFNSGRHFWEVQVGKKPKWAIGICKADSSIGERQ-SPNPWGYWRIVWQGDSFNVSGADPDSRLKAARATS-IGVFLDYELGEVSFYGMPEKCHLYTFRDTFSGPVCPYFYIG-----PQSEPLRLCSATDSEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GIM4-1", "uniprot_id": "A0AC58GIM4_DANRE", "id": "A0AC58GIM4-1", "name": "", "aln": "MRRHVQTSLTKSDVMRETPANFQQDQNPETPPILSPSQQESQSRRARRTEQSMSSSLPAQNKMDKQKLRPEIPPRVSKSSAQRLSRDLTCSICLDLFKQPVSLPCDHTFCEACITSYWSGPRVKCQAGSGSCPQCRKVFHGKSYRPNRIVANIVESYCQGMEESGVRLGAVSEPAPTAPLCMRHREELKLYCEEDQELVCLVCGISQDHRAHTLVCVQDAQKRYRASLTTSANALQKELNTALECERETEEEVKKLKDHTADLKQRIEAQFSELHQFLYQEEKLLQVKLKTEERRELIRLDEHKALLSVEISRLRRAVNDIEDKLSEQDPYTLLRSIKGLLQRQPPKFERPTLTPPSLCEGRFAGPLQYRVWKSLKGSIYPVPSAITFNSKTANPWLSLTSSLTCVRYQTFNSSVQDNPQRFNAALSLMGGQGFTKGRHYWEVEVYSSTVWTVGVARESVTRKGVINTMPANGFWTLSLSYGVQYMAGTSPPTLLSLEEPLARIGVYLDYKRGLVSFYNAESMTHLYTFRDTFTETLFPYFNLGFLDKVHENEPLKVFMPKI---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. : .*.**** :.:**:: *.*.**.:** . * . .** **: : *.* :..::* : .. :. * :*.: *.::*::* ::* * . .* * : : .* :* : : *: :: .:. *:: . :..: :: ..* :** :*:: :* ** :* : : :. : *: : .: * . :* :* : : *:: . * . : * ** .:*: * . : :: :**:* * ::.. . * : . .. : . .. *. ::* * .***:**::* ... *::*:.: . . : * : . . .*: * . * .. : **::***: * :***. . *: ** ***: .: *** :* :.:**:: . ", "identical_positions": 95, "similar_positions": 156, "identity": "16.81%" }, { "cls_id": "homologset.agr.HGNC:32687", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2A7-1", "uniprot_id": "A0A0G2K2A7_RAT", "id": "A0A0G2K2A7-1", "name": "Mediator of RNA polymerase II transcription subunit 11", "aln": "MATYSLANERLRALEDIEREIGAILQNAGTAILELSKEKTNERLLDRQAAAFTASVQHVEAELSAQIRYLTQVATGQPHEGSSYSSRKDCQMALKRVDYARLKISDVART-------CEQMLEN--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8C6-1", "uniprot_id": "MED11_MOUSE", "id": "Q9D8C6-1", "name": "Mediator of RNA polymerase II transcription subunit 11", "aln": "MATYSLANERLRALEDIEREIGAILQNAGTAILELSKEKTNERLLDRQAAAFTTSVQHVEAELSAQIRYLTQVATGQPHEGSSYSSRKDCQMALKRVDYARLKISDVART-------CEQMLEN--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P086-1", "uniprot_id": "MED11_HUMAN", "id": "Q9P086-1", "name": "Mediator of RNA polymerase II transcription subunit 11", "aln": "MATYSLANERLRALEDIEREIGAILQNAGTVILELSKEKTNERLLDRQAAAFTASVQHVEAELSAQIRYLTQVATGQPHEGSSYSSRKDCQMALKRVDYARLKLSDVART-------CEQMLEN--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNK7-1", "uniprot_id": "MED11_DANRE", "id": "A3KNK7-1", "name": "Mediator of RNA polymerase II transcription subunit 11", "aln": "-----MANDRLRALEDVEKEIALVLQSAGTIVLELSKEKANASLLDRQLNQFQTSINRVESELSSQIRYLTQVATGQPHEGSTYSARKDCQMALNRAEYARVKLGELGRT-------CEMMLDPQT------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVS4-1", "uniprot_id": "MED11_DROME", "id": "Q9VVS4-1", "name": "Mediator of RNA polymerase II transcription subunit 11", "aln": "----MNPLDKIHALDEIEKEIILCMQSAGQALQELGKEKSSQKNAETQSQQFLKSLSSVESKLSEQINYLTQVSTGQPHEGSGYASAKVLQMAWHRIQHARSRVRELEETKAKHSHAARQQLKRQQEHAAAQQQQQQQQQQQQQQQQMQQAAQQQQQQTGGGNAGSGDHPMGGDSSMSTN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::::**:::*:** :*.** : **.***:. : * * *:. **::** **.*****:******** *:: * *** :* ::** :: :: .* .. *. ", "identical_positions": 45, "similar_positions": 35, "identity": "25.0%" }, { "cls_id": "homologset.agr.HGNC:32689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "V9GXG1-1", "uniprot_id": "SLN14_MOUSE", "id": "V9GXG1-1", "name": "Protein SLFN14", "aln": "---------MPYAEITVNLGKVTLGEENRKKMTNSCLKRHENSSLVQAVCALLNSGGGVIKAEINDKSYSYRCHGLGQDLETSFQKLLPSGSQKHLDYMQQNHDLLIFVKSWSPDASSLPLRICSLRSNLYQRDVTSAINLCANGALELLREKESRAQRGTPRLHSQD--HILNRTIQEEEDIKMCALEFLKKDKLNFKEKLSFTESTHVEFKRFTTKKIVPRIKETLAHYVSAFANTQGGYIIIGVDDKSKEVFGCKKEKVNPDSLKTEIKNCIEKLPTYHFCREKPKVNFTTKILKVYQKEALYGFVCVVQVEPFCCVVFAEDPDSWIMENNIVTRLKVQQWVEMMLDIQSDPSSGFPTINDSAHLMTPALSAPRRPAYLTKVLEHKETLQRHFFSVTQENLQFQPESLCKKLFSDHEGLEDLLKAQTHPCSHGIVIFSRSWAGDIGLMREEKVLCDALLVAVGSPLVLYTILTDPSSTGRADYTQNTALQLKRQLQTLGGYPGKICVIPRVIYLASRGSRPDQPPVYYPRPYTLSSKAEVEDLLQGLVLVSLCSRSVLSDQLGCEFFKQCLEEQANTLSRNLQESRELFIHCLPGTRKTALAIKMVEKIKDVFHCKPKEILFVCENDSLRDFVMQQVTCRAVTRRTFMREEFPKIKHIVMDETENFCSRHGDWYVKAKSTTHPKANGAANEHPHHGILWLFLDPFQVRHADGSGLPVPSAQFPRKMITSEIHCAVEIAKVMKDEMKRMQENPPSMGLPDTLATFQEAPYEEAMRAGALPGVCEIKANLTPEQIANYVAEKCHSLFHEGYLPQDIAILYRRREDRGQYKDVLLKAMARGTT----EVAFNSAADVCADGIILDSVEQFSGMVRNIVFGLCPESVHSEGVHKLCFASKAIKHLYLLYGGRTAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7P3-1", "uniprot_id": "SLN14_HUMAN", "id": "P0C7P3-1", "name": "Protein SLFN14", "aln": "MESLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKAEIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLRICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPS--LVTDYNSCLISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLRYPRSYRLADEEEMEDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIETHRPSEVVFSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHKLCFASRAIKHLYLLYEKRAAY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.*: *::*:* :*************** *** :::*:***************:**:***:**********************:******.*:***********. **************:*********.*..******** ***** **::. . ::*** ******::: * **:***** :****.****************::***** *.*************::**********.*** ****** **.**:********:*** ************:****:.* *:***:************ ******::* ****..:*** **** ** *.* . : .: *::.* ** : *.* ** :.**:****:*.****::**:************: **.*:*: ****:************:*: :*::*******:**.**:****** **. .* :*::*** ***::***:***.**:*:***:*:*:* ***.: *: ***.* *:.: *:*****.**:***.***:****:*****: : **:: **..**::*****:*:**.********::*****:*********:***.***:*** **.**:****:***: ** ***************::*:**:***. *****:*:..*: *************::*** .*** ******** *** ****:*******:****::***** ***** *.*:.**** * ******* *:***.********.******: ****:***** ** ****:*: .***** * **.*..*:.* .. *:***::****: *.:****.**. :** .*******:********* *:*:", "identical_positions": 634, "similar_positions": 179, "identity": "69.37%" }, { "cls_id": "homologset.agr.HGNC:32690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAE3-1", "uniprot_id": "D3ZAE3_RAT", "id": "D3ZAE3-1", "name": "", "aln": "-----MEVLVGPGPRQAGGGLGAARSTSSGRAARTTEVPWARFSAWLECVCVVTFDLELGQALELVYPSDFRLTDKEKSNICYLAFPDSHSGCLGDTQFSFRMRQCGGQKSLWHVDDRSYNSKAPLALQREPAHYLGYVYFRQVKDSSVKRGYFQKSLVLVSRLPFVRLFQSLLSLIAPEYFEKLAPCLEAVCNEID-QWPAPVPGQTLNLPVMGVVIQVRIPSRVDKLESSPP--------KQCDQENLLPAPVVLTSVHELDLFRCFRPVLTHVQTLWELMLLGEPLVVLAPSPDVSSELVLALTSCLQPLKFCCDFRPYFTIHDSEFKELTTRTQAP---PNVVLGVTNPFFIKTLQHWPHVLRIGEPK--------------------------MSGDLPKQVKLKKPSRLKTLDTKP---------GLYTSYTAHLHRDKALLKRLLKGIQKKRPWDVQSALLRRYLLELTQSFIIPLEHYMASLMPLQKNITPWKSPPQICPFRQDDFLQSLEHAGPQLTCILKGDWLGLYRRFFKSPHFDGWYRQRHKEMAQKLEALHLEAICEANIEAWMKDKSEVEVVDLVLKLREKL--VRAQGHQLP-VKEVTLQRVQLYIDTVIGSLPKDLQAVLCPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9V7-1", "uniprot_id": "DEN6B_MOUSE", "id": "Q9D9V7-1", "name": "Protein DENND6B", "aln": "-----MEVPVGPGPRQAGGGLGATRSSSSGRAARTAEMPWARFSAWLECVCVVTFDLELGQALELVYPSDFRLTDKEKSSICYLAFPDSHSGCLGDTQFSFRMRQCGGQRSLWQVDDRSYNNKAPLALQREPAHYLGYVYFRQVKDSSVKRGYFQKSLVLVSRLPFVRLFQSLLSLIAPEYFEKLAPCLEAVCNEID-QWPAPVPGQTLNLPIMGVVIQVRIPSRVDKLESSPP--------KQCDQENLLPAPVVLTSVHELDLFRCFRPVLTHVQTLWELMLLGEPLVVLAPSPDVSSELVLALTSCLQPLKFCCDFRPYFTIHDSEFKELTTRTQAP---PNVVLGVTNPFFIKTLQHWPHVLRIGEPK--------------------------MSGDLPKQVKLKKPSRLKTLDTKP---------GLYTSYTAHLHRDKALLKRLLKGVQKKRPWDVQSALLRRHLLELTQSFIIPLEHYMASLMPLQKNITPWKSPPQICPFRQDDFLRSLEHAGPQLTCILKGDWLGLYRRFFKSPHFDGWYRQRHKEMAQKLEALHLEAICEANIEAWMKDKSEVEVVDLVLKLREKL--VRAQGHQLP-VKEVTLQRAQLYIDTVIGSLPKDLQAVLCPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEG7-1", "uniprot_id": "DEN6B_HUMAN", "id": "Q8NEG7-1", "name": "Protein DENND6B", "aln": "-----MDALLGTGPRRARGCLGAAGPTSSGRAARTPAAPWARFSAWLECVCVVTFDLELGQALELVYPNDFRLTDKEKSSICYLSFPDSHSGCLGDTQFSFRMRQCGGQRSPWHADDRHYNSRAPVALQREPAHYFGYVYFRQVKDSSVKRGYFQKSLVLVSRLPFVRLFQALLSLIAPEYFDKLAPCLEAVCSEID-QWPAPAPGQTLNLPVMGVVVQVRIPSRVDKSESSPP--------KQFDQENLLPAPVVLASVHELDLFRCFRPVLTHMQTLWELMLLGEPLLVLAPSPDVSSEMVLALTSCLQPLRFCCDFRPYFTIHDSEFKEFTTRTQAP---PNVVLGVTNPFFIKTLQHWPHILRVGEPK--------------------------MSGDLPKQVKLKKPSRLKTLDTKP---------GLYTAYTAHLHRDKALLKRLLKGVQKKRPSDVQSALLRRHLLELTQSFIIPLEHYMASLMPLQKSITPWKTPPQIQPFSQDDFLRSLEHAGPQLTCILKGDWLGLYRRFFKSPHFDGWYRQRHKEMALKLEALHLEAICEANIETWMKDKSEVEVVDLVLKLREKL--VRAQGHQLP-VKEATLQRAQLYIETVIGSLPKDLQAVLCPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4D1-1", "uniprot_id": "Q9W4D1_DROME", "id": "Q9W4D1-1", "name": "UDENN domain-containing protein", "aln": "MSADARIKQMAPSLDTTEREREHQNVDATNSNSEPSASDWVNFSQWMHCFCVVTFDLNLGQALEHVYPPAFMPSDQEVSNICYMAFPDSNSGCMGDTKFHMRLR-CTTRRDSLPG----YNAECSPALRQDGSHYWGFVYFRQKRDANLPRGYFQKSFIIITRLPFFNLYYDILSQLAPRYFEEGTDVLRLASEQINRQWPGLRVGKPLQLPLLDCSYQICIPRTSSSRKSTADGGIAGGAVESPPAMAACPAAKVLASVNEIELFRSLDFVMEQLYTLWELVITAEPIVVVGTSPADCSHMVQTLLAMIAPLEYCAEARPYFTIHDSEFREFTQECSSKTTLPACILGVTNPFFVKLLKDWPHMLRLVDNQKNMQQQQHLLLGQKHARNIASATSFSSSTELGGRIALKSNTNLNGSSSSSNGSGDASSAGLHSKYRPYLKKDKALIKKVLLGMKTKRPEHVQTALIRRHLLELTQSFMIPLERYMASLMPLQKDISPFKSAPNANSFKLDDFLGTLETAGPQLTSPLKGDWKGLYRRFFRSPNFRGWYGARHRELQLTLQDLQLQALSVANLEHWAHDKQEVEIIDMILKLKQKLNLYGDKATQLEGNNGSTQQQIRAQIECMKGLLPPDLKNVVNL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :... : ::. :... *..** *:.*.*******:****** *** * :*:* *.***::****:***:***:* :*:* * ::. ** ... **::: :** *:***** :*:.: *******:::::****..*: :** :**.**:: : *. ...:*: ***. *:.*:**::. *: ** .. :*:. :. **. **:**:*::***.: *: :: *****:: .**::*:..** .*.:* :* : : **.:*.: ***********:*:* . .: * :********:* *:.***:**: : : * :* :: **. :.*: .:.. **:: * .:*::****:*::* *::.*** .**:**:**:********:****:**********.*:*:*:.*: .* **** :** ******. ***** *******:**:* *** **:*: .*: *:*:*:. **:* * :**.***::*::***::** :. ** : * *: : *: : * ** **: *: ", "identical_positions": 257, "similar_positions": 185, "identity": "40.16%" }, { "cls_id": "homologset.agr.HGNC:32695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAH4-1", "uniprot_id": "D3ZAH4_RAT", "id": "D3ZAH4-1", "name": "", "aln": "MASSPLPGPNDILLASPSSAFQPDALSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTP-DAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPP-LAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAATGGAGPGAGGPGGGCVAGVGVGATAGAGAAAGTKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFGLCHKK-EDAGTAAEALGGAGAGSAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGDSPALLRQAFLDLAEPGGAGGSAEAAPPPGQPPPVVANGPGSGPP-ATGGTGSRDTLFESPPGGSGGDCSAGSTPPAEPGVTSGNGATSSGAGSVGTRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDSESLAKLHGASAGAPHSAPAHHHHHHH-HPHHHHHHPPQPPSPLLLLQPQPDEPGSERHHPAPPPPPPPPP---LAPQPHHRGLLSPEGTSCSYPSEDSSEDEEDEEEEQEVDVEGHKPLEGEEEEDGRDPEDEEEEEEETRVLLGDSLVGGGRFLQGRGLSEKGSGRDRTTPAVGAFPLALNSSRLLQEDGKLGDPGGSDLPAPPPPSLAPQKASGGGGSRPGSPVHHPSLEEEPSYKDNQKPKENNQVILSAKDDN-FSDKNKEHS-FFITDSDSSG-DFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNSSFPVFNNFQDQVKRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7M7C7-1", "uniprot_id": "SKOR2_MOUSE", "id": "A7M7C7-1", "name": "SKI family transcriptional corepressor 2", "aln": "MASSPLPGPNDILLASPSSAFQPDALSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTP-DAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPP-LAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAATGGAGPGAGGPGGGCVAGVGVGASAGAGAAAGTKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFGLCHKK-EDAGTAAEALGGAGAGSAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGDSPALLRQAFLDLAEPGGAGGSAEAAPPPGQPPPVVANGPGSGPP-ATGGTGARDTLFESPPGGSGGDCSAGSTPPAEQGVTSGTGSASSGAGSVGTRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGTPHSAPAHHHHHHH-HPHHHHHHPPQPPSPLLLLQPQPDEPGSERHHPAPPPPPPPPP---LAPQPHHRGLLSPEGTSCSYPSEDSSEDEEDEEEEQEVDVEGHKPLEGEEEEDGRDPEDEEEEDEETRVLLGDSLVGGGRFLQGRGLSEKGSGRDRTTPAVGAFPLALNSSRLLQEDGKLGDSGGSDLPAPPPPPLAPQKASSSGGSRPGSPVHHPSLEEEPSYKDNQKPKENNQVIISTKDDN-FSDKNKGHG-FFITDSDSSG-DFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNTSFPVFNNFQDQMKRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2VWA4-1", "uniprot_id": "SKOR2_HUMAN", "id": "Q2VWA4-1", "name": "SKI family transcriptional corepressor 2", "aln": "MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTP-DAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKK-EDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPG-SDLPPPPPPPLAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHS-FFITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNTSFPVFNNFQDQMKRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TYK6-1", "uniprot_id": "A0AB32TYK6_DANRE", "id": "A0AB32TYK6-1", "name": "", "aln": "MDKSLLPGPKDIVMATPPSSFQQEPLTPPR---SSLKPNQVGQVILYGVPIVSLVIDNQERLCLAQISNTLLKNYSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENSPPKLPDNFAFEVMHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTP-EAKYTQPDAANFNSWRRHLKLAEKTPPDDLMFAWEDVKAMFNGGSRKRALPS----SHCSSMSAVKAVNSVLPHMIS------------------------------PELTQKRGRYEDDDD-------LDSNSLSP------------------------------------------RKAPRSYPVIPVPSKG-FG-MLQKFP-TTSLFPSPYTFP----AFGLCPQK-KDD---SEASNGQ--------KNNSLSGLLWP-GRKDAFYPPFCMFWPPRATGGIPVPTYLQPQPNALSSL----TESPS-LRQAFLDLSEQGDAGSGLDTNP--------------------------RSGLFDS-------DCPP---------VTSELRPAPEG------------WLKLLDTPSLQARKASYHSAFRPV--VKDTESIAKLHGS----------------------------------------LEDFGPERH-------------------------LSP-GTSCSYQS-----DSAESDEEQEVDVETKQ--------------DEEQEDFGSRVAQTPPQPCG---LHMRGLPDSQTTAEQAKELA-SFPSIPAETPAEDKPG---------LAVSPPTILKVP-----------SPVHG-SLEESAAYRNAHKSRDDGLPAYATKNKTAASDDNKEQSSFFVSETETSAPEYWRENPTDQSQEANSPVSLKKDVENMEKEELQKVLLEQIDLRRRLEQEFHALKGSSPFPVFHNFQDQMKRELAYREEMVQQLQMIPYAN-IIRKEKVGTHLNKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D1YSG4-1", "uniprot_id": "D1YSG4_DROME", "id": "D1YSG4-1", "name": "", "aln": "---------MDLNENFKMASISVAHFDRMENCQTSQRSNHVSSVLLYGVQIVSLHIEGQERLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPVSSRRCGMITRREAERLCKSFLGDNTPPRLPDDFAFNVQHKCAWGCRGSFLPSRYNSSRAKCIKCSYCGMFFSPNKFIFHSHRITTNDRYVQPDAANFNSWRRHMSLSGNDYDEKIIHAWEDVKAMFNGGTRKRLVGSSINPRSPGSPTQSTAVSSGVGSSSCG-----------------------------SPTSFERDTNEVDGK--------SGSSLPQR-----------------------------------------SQIDSQYNYGTVAAAAAVVGVTAVAAATVGVPFNLHGSTVLSPLHSLRNERDLSIMPISRNFVVDYMWQQKDQHYQQPYARKIPSGDNSDSSLDFDSWVKPDSNNPIPNANSVRTSDNCSFNIK---NESHSSIYGIIKNHKLSGVPNSGLNLSDYN------------------------IPSILNCSAFKPVVASTAIVSTSLYTRSNESTRTDCNN------------PAQSTRTTTVLTHNSISASSHQIVGHKTFSPILGKIHSN--------------------------------------------------------------------------PEKNRIVSVFASSSTGNADDNDDDDEVVDIETTE------------------DEGKFTVQHADSPKTQYDAISGSDSPSRSPSTSTNIDVEQDVDVDIITTDTEDQLELS-----------------------VGRYSTENTSHSLSFFQAEKIQISDLSPNTKTSSGDNETNTLKDAKGINGNLQILARRKRNKLQKDRCLSKRTVSKCVSDKSLIKGLAAN-ELSSSLQIQQHVAFPVFLKSQLHSLRPQQAQQVVSLTTNSVAESNKWSYPVGNIEPLCCYQTSGNKNSLV-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :::. : . :. :.*:*..*:***: **** *:.***************::**********************************:*********:************:* **:***:***:* *:*********:*:***************.*:************ . : :*.*************:.*: : :.::.************:*** : . . : .*. . . :* : *.. . **. : .* .*.: . . : . .: : . ..* :: . :. . * * :. * : * : . :* .. ::. : : :* : : : : * . .. : :::. ... . . : . . *:.: * : :.*:*. . . : * . :.:::: **:* : :: * . : . .. . . . : :: .. * *: : : . . : : .. . .. . ::: . . : * . .: * ** *.: : . . : ::: : *:.::: *: . . *. :.: .. : : : : * ::. : ", "identical_positions": 196, "similar_positions": 203, "identity": "19.23%" }, { "cls_id": "homologset.agr.HGNC:32696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1B8-1", "uniprot_id": "DCD2C_MOUSE", "id": "Q9D1B8-1", "name": "Doublecortin domain-containing protein 2C", "aln": "MGTRGPYALVDTTPAKTILVYRNGDQFYVGRKFVFSRRRVANFEALLEQLTEQVEVPFGVRRLYTPTRGHPVLGLDALQTGGKYVAAGRERFKKLDYIHIVPRKPSKMRKLKEIKPVVHCDIKVPSRWQIQSRTSRYINVFTNGRLFIPPIKVIIPKFSLSDWNSVLAMIGEKVFPLGGVRKLFTMDGHLLDDSKNLQDNYFYVAAGLETFKSIPYWKSSWVPSEVQQRFGGNDKYTQTKKRVESKVKEPLQNDSVPPRSQDSVYYAKE-KKQMDTELLVQSGAEGDVYKAQTPAKEAQEALEVKEDPEVKVEVPVDQAPAEIVKEIDEIGDSSPGLKSGMHIPASFM------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZV25-1", "uniprot_id": "A0A8I5ZV25_RAT", "id": "A0A8I5ZV25-1", "name": "Doublecortin domain-containing protein 2C", "aln": "MGTRGPYALVDTTPAKTILVYRNGDQFYVGRKFVFSRRRVANFEALLEQLTEQVEVPFGVRRLYTPTYGHRVLELESLQTGGKYVAAGRERFKKLDYIHIVPRKPTKMRKLKEIKPVVHCDINVPSRWQTQSRTSRYINVFTNGRLFIPPIKIIIPKFSLSDWNSVLAMIGEKVFPLGGVRKLFTMDGHLLDDSKNLQDNYFYVAAGLESFKSIPYWKSSWVPSEVQQRFGRNDKYTQTKKRVEYKGKEPLQSDSVPPKIQDSVYYAKE-KKQMDTEPLIESGAEGDVYKAQTPAKEAQEALEVKEDPDMKVELPVDQAPAEIVKEIDEIGSGSPGLESGMEKEMERLYEDIDRKHLSRASSRIKRWFQRLKKYDMTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MYV0-1", "uniprot_id": "DCD2C_HUMAN", "id": "A8MYV0-1", "name": "Doublecortin domain-containing protein 2C", "aln": "MGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFTMNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVPSEVQQRYANVEKNSQRKKKVDSKGKEPCKYDGIPPKTQDSVYYAKEEKKKTLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQRQAEIVKEDEEIHENTPDFEGNKDKEDARLCEDVERK-MAREWKPVD-------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** * *********:****** ****:***:****.*.************:********:*** ** ** *::**:*************:***********:*:**************:***:** * **:************* *:**********: *** *****************:****.***:****:****.***:** :*****. ********:. :* :* **:*: * *** : *.:**: ********* **: :* *:: ********* **:**:* **:***: ::::*:**** ****** :** ..:*.::.. . : ", "identical_positions": 246, "similar_positions": 60, "identity": "65.08%" }, { "cls_id": "homologset.agr.HGNC:32697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYT9-1", "uniprot_id": "A0ABK0LYT9_RAT", "id": "A0ABK0LYT9-1", "name": "", "aln": "---MGDLKSGFEEVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRTTVHKRMDHLKVKKHHCDLEELRKLKAINSIAFHAAKCTLISREDVEALYTSCKTERVLKTKRRRVGRALATKAPPPERAAAASPRPAFWKDKHQLWRGLSGAARPLPISAQSQRPGAAAARPAAHLPQIFSKYPGSHYPEIVRSPCKPSLNYETAPLQGNYVAFHSDPAYFRSLLCSKHPAAAAAAAAAAAAAAAAAAYYQ-----AAGPQPKAATGAGGPVSLTYRCKRKRGGAKNCLLAPHTGARRLLLLPRSYKAKAAAAAAAAAAAAAAAAGATCLERFHLVNSFCPPPHHHHHHHHHHHHHHHRAQQPTPSHHPPHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSDFGSSLSSSSNSVSSEEEEEEGEEEEEEEEEE-GGSGASDSSEISSEEEDSSTESDSSSGSSQVSVQSIRFRRTSFCKPPSVQAQANFLYHLASAAAAAKPAAFEDAGRLPDLKSSVKAESPEEWNLQSWAPKGAPVYCPASLGSCFPEIRNDRVSEITFPHSEISSTVKRTDLTVNCQAEGASSPSPKTNNVFPQQRILREARKCLQATPTTHCAENSTMAARFLNNDSCGTAANSGKDSKIPHCPEFATDLPSPQTDPGVDAAAAAAAAAAAAAAAAAATKAESLCTDTGD---KTLPFLHN-IKIKVEDSSANEDYEPDLITSELKWECNDTEGEFYSVTEKKEEDALVPTAKEGFACPEKETPSLNPLAQSQGLSCTLGSPKPEDGEYKFGARVRKNYRTLVLGKRPVLQTPPVKPNLKSARSPRPTGKTETHEGTLDDFTVLNRRKKVASNVASAVKRPFNFMANFPCPPSLIIGKDGDLWPAYSLNTTKDSQPPHKAHPIWKWQLGGSAIPLPPSHKFRKFNS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YR3-1", "uniprot_id": "SKDA1_MOUSE", "id": "Q80YR3-1", "name": "SKI/DACH domain-containing protein 1", "aln": "---MGDLKSGFEEVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRTTVHKRMDHLKVKKHHCDLEELRKLKAINSIAFHAAKCTLISREDVEALYTSCKTERVLKTKRRRVGRALATKAPPPERAAAASPRPAFWKDKHQLWRGLSGAARPLPISAQSQRPGAAAARPAAHLPQIFSKYPGSHYPEIVRSPCKSSLNYETAQLQGNYVAFHSDPAYFRSLLCSKHP--------------------------------------------------------------------------------------------AAAGATCLERFHLVNSFCPPPHHHHHHHHHHHHHHHRAQQPTPSHHPSHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSDFGSSLSSSSNSVSSEEEEEEGEEEEEEEEEEEGGSGASDSSEISSEEEDSSTESDSSSGSSQVSVQSIRFRRTSFCKPPSVQAQANFLYHLASAAAATKPAAFEDAGRLPDLKSSVKAESPEEWSLQSWAPKGTPVYCPASLGSCFPEIRNDRVSEITFPHSEISSTVKRTDLTINCHAEGASSPSPKTNNVFPQQRILREARKCLQATPTTHCAENSTIAARFLNNDSCGTTANSGKDSKIPHCPEFATDLPSLQSDPRVDTAT-------AAAAAAAATKAESLCTGTGD---KTLPFLHN-IKIKVEDSSANEEYEPELITNKLKWECNDAEGEFYNMTEKKEEDALVPTAKEGFACPEKETPSLNPLAQSQGLSCTLGSPKPEDGEYKFGARVRKNYRTLVLGKRPVLQTPPVKPNLKSARSPRPTGKTETHEGTLDDFTVLNRRKKVASNVASAVKRPFNFMANFPCPPSLIIGKDGDLWPAYSLNTTKDSQPPHKAHPIWKWQLGGSAIPLPPSHKFRKFNS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1XH10-1", "uniprot_id": "SKDA1_HUMAN", "id": "Q1XH10-1", "name": "SKI/DACH domain-containing protein 1", "aln": "---MGDLKSGFEEVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRTTVHKRMDHLKVKKHHCDLEELRKLKAINSIAFHAAKCTLISREDVEALYTSCKTERVLKTKRRRVGRALATKAPPPERAAAASPRPGFWKDKHQLWRGLSGAARPLPISAQSQRPGAAAARPAAHLPQIFSKYPGSHYPEIVRSPCKPPLNYETAPLQGNYVAFPSDPAYFRSLLCSKHPAAAAAAAAAAAAAAAAAAAAAYYQVSAAGPQPKAAAGAGGPGSLSYRCKRKRGGAKDCLLAPHAGARRLLLLPRSYKAKAAAAAAAAAAAAAAAAGATCLERFHLVNGFCPPPHHHHHHHHHHHHHHHRAQPPQQSHHPPHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSDFGSSLSSSSNSVSSEEEEEEGEEEEEEEEEE-GGSGASDSSEVSSEEEDSSTESDSSSGSSQVSVQSIRFRRTSFCKPPSVQAQANFLYHLASAAAATKPAAFEDAGRLPDLKSSVKAESPAEWNLQSWAPKASPVYCPASLGSCFAEIRNDRVSEITFPHSEISNAVKRTDLTINCLAEGASSPSPKTNNAFPQQRILREARKCLQTTPTTHCADNNTIAARFLNNDSSGAEANSEKYSKILHCPEFATDLPSSQTDPEVNAAG------------AAATKAENPCTDTGD---KTLPFLHN-IKIKVEDSSANEEYEPHLFTNKLKCECNDTKGEFYSVTESKEEDALLTTAKEGFACPEKETPSLNPLAQSQGLSCTLGSPKPEDGEYKFGARVRKNYRTLVLGKRPVLQTPPVKPNLKSARSPRPTGKTETNEGTLDDFTVINRRKKVASNVASAVKRPFHFMANFPCPPSLIIGRDGDLWPAYSLNTTKDSQTPHKAHPIWKWQLGGSAIPLPPSHKFRKFNS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSP4-1", "uniprot_id": "A0A8M1PSP4_DANRE", "id": "A0A8M1PSP4-1", "name": "", "aln": "MKKMGDLESGFEEMQGVKLGYLIIKGKQMFALSQVFTDLLKNIPRTTVHKRMDHLNVKKHHCDLEELRKLKAINSIAFHAAKCTLISREDVEALYFSCKTERVLKSNKRRD-KTKTSSEKMCDGKNYTSAKSDFWREK--VWLSLHGVPQTFSFKNKAVRQ-DPVSRSHSNLPQIYSKSFARDFQPVAKSASTPFKNYETDQIPDNYVAFNQKHTFIRHVVNRQPLLYQSAIAAPAKHQGN--------------------------ADLLYKRKRKR----------------------------------ESSARQLWSRSRRSHPVLVVPKCCKPKVSNGSLSQFHHLEHGFYVDPRNTVH-------------FQESCSSDTESSTISERVNNDSDFGSSFSTTSNSGTSDEEEED--------------DSLSDSSDVSSDEE-SSSQSESSSVSSQVSVQSIRFRRARFS-SINTKAPLLLQPTFHYRPNVQTIATNQDLTTTLDCERTGKTQKSDFGDAHENGDAANNVQKFCSVRTCFPDLREKEDSEAPLR-LEVSNDPKTTDS--NKIKEIRLTPNTLGNKAFPQQRIPASANKCSQG-LISHCVPDKEITVCKSSDSNLSLVANFKREVKT------SLKLPSPIKH--------------------IKTEAEELINNEGNRAVKTPPFLLNNVKIKVED--IFDDYEYAKQPPEYQCKDNDADGQCISDP-FKETDHWKAAESSG-----QKHPACNEESKS-----TLNARCSEEEECKNGVRVRKNYRSLLLGKKAESARTSAKSASKVDRSSRSAGKFASSEISSGDCAGTSKRKRASASVAS-LKKPFRFMANFPSPPALLIGNDGDLSPAYSLNSSRSNQLPPRSHPVWRWQLGHSVVPPPPSHKFRKASVIP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:*****::**:*************************************:*************************************** *********:::** :: ::. : :*.:. **::* :* .* *..:.:.:. :: * ..:*. ::****:** . .: :.:*.... **** : .***** .. :::* :: : : : . . :* * * : :.** .* * : * * ******:***: *::. ********:*::*** :*:****: .. ****::**:** **::*:*** *************: *. . ..:* : : . . . *: :* * : : *::.. . :. . . * .*: :**.::*:.. ** .: *:*. * ** * * :*.. *:.****** .*.** * :**. :. ::. .:.. . ** : * : .*** .. *:**. .. *: ** *** * :****** ::** . : : : **:.*: . . ** * .: ..* :: *: * ::* **.: .*: * * *.*******:*:***:. ...*. * **.*.:** : * : .* : .:**:.::.*** :*:**.******.**:*:**.**** ******:::..* * ::**:*:**** *.:* ******** . ", "identical_positions": 329, "similar_positions": 221, "identity": "35.38%" }, { "cls_id": "homologset.agr.HGNC:32698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEJ5-1", "uniprot_id": "D3ZEJ5_RAT", "id": "D3ZEJ5-1", "name": "", "aln": "MLSLIPAAGGHTLPQLVLGEEHRDITQVPHLHDALSGTTWMTAWDGVLPFYPQP-RHAAGFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSTSRVQVHVGLHVGLEGVNITLRGTPMQQLN-ETIDYNEQFTWRLNEDYTKEYVQALEKGLPDPVLYLAEKFTPNSP-CGLYHQYHYAGHYAGATLWVAFCFWIIANALLSMPAPLYGGLALLITGAFTLFSVFAFASISSVPLCHFRLGSAALTPHYGASFWVTLATGILSLLLGGLVVILHYTRPSVLRALLDQNVK---------DCSNQADGNSH---------------------------------------------------------------------------------------------------------FILDNPQHRQSKTPDLN-----VTTLL----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D311-1", "uniprot_id": "DOXA2_MOUSE", "id": "Q9D311-1", "name": "Dual oxidase maturation factor 2", "aln": "----------------------------------------MTAWDGVLPFYPQP-RHAASFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSPSRVQVHVGLHVGLAGVNITLRGTPRQQLN-ETIDYNERFTWRLNEDYTKEYVHALEKGLPDPVLYLAEKFTPSSP-CGLYHQYHLAGHYAAATLWVAFCFWIIANALLSMPAPLYGGLALLTTGAFTLFGVFAFASISSVPLCHFRLGSAVLTPYYGASFWLTLATGILSLLLGGAVVILHYTRPSALRSFLDLSVK---------DCSNQAKGNSP---------------------------------------------------------------------------------------------------------LTLNNPQHEQLKSPDLN-----ITTLL----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1HG44-1", "uniprot_id": "DOXA2_HUMAN", "id": "Q1HG44-1", "name": "Dual oxidase maturation factor 2", "aln": "----------------------------------------MTLWNGVLPFYPQP-RHAAGFSVPLLIVILVFLALAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSAEWFVGTVNTNTSYKAFSAARVTARVRLLVGLEGINITLTGTPVHQLN-ETIDYNEQFTWRLKENYAAEYANALEKGLPDPVLYLAEKFTPSSP-CGLYHQYHLAGHYASATLWVAFCFWLLSNVLLSTPAPLYGGLALLTTGAFALFGVFALASISSVPLCPLRLGSSALTTQYGAAFWVTLATGVLCLFLGGAVVSLQYVRPSALRTLLDQSAK---------DCS-QERGGSP---------------------------------------------------------------------------------------------------------LILGDPLHKQAALPDLKC----ITTNL----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYU3-1", "uniprot_id": "A0AC58IYU3_DANRE", "id": "A0AC58IYU3-1", "name": "", "aln": "MRVTEPLANTVLLSALVLACGG-----------------KMTFYDGIYPFYPLQ-RSPFMINISLLVAILVFSVLAVSFLFILPGIRGRSRWFWMFRIFISLFIGVVLVVLNFTGDWAEARVKANTTYKSFSTAVVSAEVGLHVGLYGINITLKGEPVTQIN-ETINYNEIISWSSSVD--EQYGDALERGLPNPILYIAEKFTYNSA-CGLIYQYSYSARFASANLWTAFCCWLLANILFSMPVILYAGYMMIATAAFIFFSVASFSTIYNVSPCDFSIGSEALRTDYSHSFWLALATGLLCAVIGLLVVLLDCLFPARMREAFSVGVDDEDD-----ECCADEGYLNS---------------------------------------------------------------------------------------------------------GFLEGVIHDDVTPAENNSLPQQITTLTRL--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJQ7-1", "uniprot_id": "Q9VJQ7_DROME", "id": "Q9VJQ7-1", "name": "", "aln": "----------------------------------MKGWFDAFRDDGGPTLYSFSNRTPVTGDVSIVAVSVLFATFYVAFLVIFPGVR-KQKFTTFSTVTLSLFVGLVILITRLGSAWHVAHATIIAPYKAFSREKLPARIGTHIGLMHVNVTLTAIPIGNWTPPDIDYNERFTWEGANDMSANYRHALQRGLPFPILTVAEYFSLGREGFSWGGQYRAAGYFASIMLWASLASWLLMNLLL-IAVPRYGAYMKALTGALLVCTTVGYHCLLPKRPLSIHLEGGRLEFHFGWCYWLVLVAGILCFIAGVLISIIDLVWPHTFSTVLEVYYGTPYDRHVILEESSDVRYRKPRNSRSLEDPPGLGSRILRRLSSKARDLQPGTAPRRDSPAGVSSSGGVENKGFQSDAPKSPWRYPFRRSQQMAQQQHSHPLHQHPLQQHHQHHQHHHQQQLQFVGGPVVQHPMHHMQRTMSQDSGSSIASAAVQISPLHKHALARMLPNPPVERIRDMDHW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .:*. * . .:.:: . ::* : .:**.*:**:* :.:: : : :***:* :: .: . * . . :.**:** : ..: :** :*:** . * : . *:*** ::* : :* .**::*** *:* :** *: . . ** :. :*. **.::. *:: * *: .. *.. *.*: . . . : : : . * :. .:*:.*.:*:*. . * : :. * : :. : . : . : * . . :: ", "identical_positions": 60, "similar_positions": 110, "identity": "11.76%" }, { "cls_id": "homologset.agr.HGNC:327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQR2-1", "uniprot_id": "ADAS_RAT", "id": "Q9EQR2-1", "name": "Alkyldihydroxyacetonephosphate synthase, peroxisomal", "aln": "MAEAAG-------EAGAS-------ERDPDAVRARRRLRVLSGHLLGRPQEAPSTNECKARRAASAAGASPAASPAAPESGTIPKKRQELMKWNGWGYNDSKFLLNKKGQVELTGKRYPLSGLALPTLKDWIQNTLGVNLEHKTTSKPSINPSEAPPSIVNEDFLQELK-EAHISYSQDADDRVFRAHGHCLHEIFLLREGMFERIPDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSIVGGWISTRASGMKKNVYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGFKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYVVGESFETSAPWDRVIDLCRNVKERIRRECKERGVQFAPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAARDEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPSNIFGNRNLL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0I1-1", "uniprot_id": "ADAS_MOUSE", "id": "Q8C0I1-1", "name": "Alkyldihydroxyacetonephosphate synthase, peroxisomal", "aln": "MAEAAAG------EAGAS-------ERDPDAGRARRRLRVLSGHLLGRPQEAPSTNECKARRAASAAGASPAATPAAPESGTIPKKRQEVMKWNGWGYNDSKFLLNKKGQVELTGKRYPLSGLVLPTLRDWIQNTLGVSLEHKTTSKTSINPSEAPPSIVNEDFLQELK-EARISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLGLEYYVIGESFETSAPWDRVIDLCRNVKERIRRECKERGVQFAPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEHTEAAAREEILANGGSLSHHHGVGKIRKQWLKESISDVGFGMLKSVKEYVDPSNIFGNRNLL----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00116-1", "uniprot_id": "ADAS_HUMAN", "id": "O00116-1", "name": "Alkyldihydroxyacetonephosphate synthase, peroxisomal", "aln": "MAEAAAAAGGTGLGAGASYGSAADRDRDPDPDRAGRRLRVLSGHLLGRPREALSTNECKARRAASAATAAPTATPAAQESGTIPKKRQEVMKWNGWGYNDSKFIFNKKGQIELTGKRYPLSGMGLPTFKEWIQNTLGVNVEHKTTSKASLNPSDTPPSVVNEDFLHDLK-ETNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V778-1", "uniprot_id": "ADAS_DROME", "id": "Q9V778-1", "name": "Alkylglycerone-phosphate synthase", "aln": "---------------------------------------------MAAKRNAVTTEAPESSAPGEGTALALDSRLSKRVESVIPKKRHEALKWFGWGYNDSQFYG-KDGIICFRGEKYPLGGCELPSFTKWVEKKFDLRVD--TTKQYPQLPRTYPRPVENAPFLHELKGTTQVDYSAEGIDRLVRCHGQTLNDIYSLWHHKFRRIPDLVVWPRCHDEVVQLVRLANKHNVMLVPFGGGTSVSGAITCPQNESRMICALDTSQMNRLLWLNRENLTVCFESGIVGQDLERVLRSEGLTVGHEPDSYEFSTLGGWVATRASGMKKNVYGNIEDLVVRVRMVTPSGTLERECSAPRVSCGPDFNHVILGSEGTLGVITEVVLKVRPLPSLRRYGSLAFPNFEQGVLFMREVARRRCQPASVRLMDNEQFMFGQALKPEKS-WWASVVDAMKQRYVTSWKGIDLNQICAATLLFEGDLKDVQRQEALIYEIAEKFQGFPAGGQNGERGYILTFVIAYIRDFGLHQGIVAESFETSVPWDRCSLLCRSVKQRVVSECSKRSINYYTIS-CRVTQTYDAGACIYFYFGFRSTDVADPVELFEAIEHSARDEILSCGGSLSHHHGVGKIRSHWYRNAVTETGSSLYSAAKRHLDPKNIFALGNLLPLEEAQASPPPPTSSTPPKAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ::* :*: :: ....: : : : ...*****:* :** *******:* *.* : : *::***.* **:: .*:::.:.: :: **.: . * * .: * **::** :.:.** :. **:.*.**: *::*: * . *.****:*:** ***:**::*.** *:*: ::*:******* .: ** :*:* * :********:**::.:***. .*:**.**:*** *:..* .****** *** :***::*********:*********:::**** * :*:....**:* ***::*.*:***********..:*:** *. ::***:********* :**:*::** ***:*****:** **:****: * ::*.:*.:*: *:*.:**:* **:..******** :.* ::* :*:** ** *:.** :**:***:**:****:**:.*. ::.******.**** ***.**:*: **.::.::: .:* *****************.*. .::**: :** * :**:***: ************:*.:* ::::::.* .: .:.* ::**.***. *** ", "identical_positions": 307, "similar_positions": 201, "identity": "45.08%" }, { "cls_id": "homologset.agr.HGNC:3270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UGC7-1", "uniprot_id": "EI3JA_MOUSE", "id": "Q3UGC7-1", "name": "Eukaryotic translation initiation factor 3 subunit J-A", "aln": "--MAAAAAAAAAAGDSDSWDADTFSMEDPVRKVAGGGTAGGDRWEGEDEDEDVKDNWDDDDDENKEEA---EVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR-LEEPEESKVLTPEEQLADKLRLKKLQEESDLELAKETFG------------VNNTVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSL---YYASFLEALVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKA-KKKKKGVVPGGGLKATMKDDLADYGGYEG----------GYVQDYEDFM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66JS6-1", "uniprot_id": "EI3JB_MOUSE", "id": "Q66JS6-1", "name": "Eukaryotic translation initiation factor 3 subunit J-B", "aln": "MAAAAAAAAAAAAGDSDSWDADTFSMEDPVRKVAGGGTAGGDRWEGEDEDEDVKDNWDDDDDENKEEA---EVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR-LEEPEESKVLTPEEQLADKLRLKKLQEESDLELAKETFG------------VNNTVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSL---YYASFLEALVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKA-KKKKKGVVPGGGLKATMKDDLADYGGYEG----------GYVQDYEDFM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0JPM9-1", "uniprot_id": "EIF3J_RAT", "id": "A0JPM9-1", "name": "Eukaryotic translation initiation factor 3 subunit J", "aln": "----MAAAAAAAAGDSDSWDADTFSMEDPVRKVAGGGTAGGDRWEGEDEDEDVKDNWDDDDDENKEEA---EVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR-LEEPEESKVLTPEEQLADKLRLKKLQEESDLELAKETFG------------VNNTVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSL---YYASFLEALVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKA-KKKKKGVVPGGGLKATMKDDLADYGGYDG----------GYVQDYEDFM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75822-1", "uniprot_id": "EIF3J_HUMAN", "id": "O75822-1", "name": "Eukaryotic translation initiation factor 3 subunit J", "aln": "-----MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEA---EVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR-LEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFG------------VNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSL---YYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKA-KKKKKGVVPGGGLKATMKDDLADYGGYDG----------GYVQDYEDFM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXU0-1", "uniprot_id": "EI3JA_DANRE", "id": "Q7SXU0-1", "name": "Eukaryotic translation initiation factor 3 subunit J-A", "aln": "------------MADADSWDADSFEPEEPIKKAAVH-----DKWEGEDEDDDVKDNWDDDEEEEKEEE--EEKKTEAKPTEKKKLSEKIKEKENLQRKKQEELRKQQLEETKRDTPLTPEDELAEKLRVKQLQEDSDLELAKEAFG-----------VVSNNVTGIDAVSPSSKDDFTEFERLLKEKISPYEKSI---HYSGFLETLFRDLCLSLEVEDLKKINNSLTVLLSEKQRQEKANKG-KKKKKGVLPGGGLKAKMKDDLADYGGFDG----------GYAQDYEDFM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q803P1-1", "uniprot_id": "EI3JB_DANRE", "id": "Q803P1-1", "name": "Eukaryotic translation initiation factor 3 subunit J-B", "aln": "------------MADSDEWDADNFEPNEPIKIATAGR---LDRWEGEDEEEDVKDNWDDEEEEKEEEKKVEQKIAEVKPPEKKKLSDKIKEKELLQKKKQEELKKN--QETAASESLTLEEQLAEKARLKKLQEEADMELAREAFGVDPAAANASTTVNTTNASGIEAMCPSSKDDFVTFEKLLKEKITQFEKSV---HYPSFLESLFRELCISLEVDDLKKISTSLSVLLTEKQKQEKEKKANKKKKKGVVPGGGLKANMKDDFADYGGFDG----------GYGNEYDDFM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K550-1", "uniprot_id": "EIF3J_DROME", "id": "Q7K550-1", "name": "Eukaryotic translation initiation factor 3 subunit J", "aln": "------------MADDWESAADSEVVIRPTAAASVN------KWEGEDEDEDIKDSWEDEEEKKDEEK-----PTKTEAPAKPKPNKALKAKLEQQALLEEEAEAK------RLANLSPAEKLAEKLRLQKIQEASDLKHAQEAFG------------VTSTCGGLDAFNPETKEEFKEFGATLSWKVGQFRESE---HFPQFVEDLVRSLCVNLSAADIKKVKMNVEILHSEKLKLEKANAK---KPAGKGKGKVTLRTENDDIDGYQKYGN----------DFTEDYDDFM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05775-1", "uniprot_id": "EIF3J_YEAST", "id": "Q05775-1", "name": "Eukaryotic translation initiation factor 3 subunit J", "aln": "-------MSWDDEAINGSMGNDDAVLMDSWDAEIGDDEPVMQSWDAEEEEKKPAPKPKKEQPKKVKKG------KESSADRALLDIDTLDEKTRKELIKKAEMESDLNNAADLFAGLGVAEEHPRARALQKEQEEQ--ALKRPAFT------------KDTPIETHPLFNAETKREYQDLRKALTAAITPMNKKSPLNYSSSLAIDLIRDVAKPMSIESIRQTVATLNVLIKDKEREERQARL-ARVRGGTATGGAGKKKVKGKTNLGGAFKKDQDFDLDGPDDFEFGDDDFM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . *:.*:*:.. . ..:: :: :: : . . :. * : : * . * :: . ::: ** : :* . . ..:: :: : *. : .:. : . : *.*.:. :. .::: .: :* .:* : *: * * . :.. : .: :***", "identical_positions": 21, "similar_positions": 76, "identity": "7.17%" }, { "cls_id": "homologset.agr.HGNC:32700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8H9-1", "uniprot_id": "D3Z8H9_RAT", "id": "D3Z8H9-1", "name": "", "aln": "ME--KTDVINFKALEKELQAALAADEKYKRENAAKLRAVEQRVPSYEEFRGIVLASHLKPLEQKDKVG-GRRFVSWNCHTTREKTSQDVVTEMPQEKSPVQPTTSAEFYRDWRRHLRSGSERYQALLQLGGSKLGHLFQTDVGFGLLGELLVALAEHVKPSDRRAVLGILHSLANTGRFTLNLSLLSHAERESCQLLFQKLQAMG-TTRPMQEGLSMEEP-----SAGLQGEEG-------LLQELLGLYGIH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9P2-1", "uniprot_id": "DAA19_MOUSE", "id": "Q9D9P2-1", "name": "Dynein axonemal assembly factor 19", "aln": "ME--KNDVINFKALEKELQAALAADEKYKRENAAKLRAVEQRVPSYEEFRGIVLASHLKPLEQKDKMG-GKRFVPWNCHTTRERTSQDVVTEIPQEKSPFQPTTSAEFYRDWRRHLRSGPERYQALLQLGGPKLGHLFQMDVGFGLLGELLVALAEHARLSDRTAVLGILHSLANTGRFNLNLSLLSHAERESCQRLFQKLQAMS-TTRPMQEGLTVEEP-----SAGLQGEEG-------LLQELLELYGVH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IW40-1", "uniprot_id": "DAA19_HUMAN", "id": "Q8IW40-1", "name": "Dynein axonemal assembly factor 19", "aln": "ME--RNDIINFKALEKELQAALTADEKYKRENAAKLRAVEQRVASYEEFRGIVLASHLKPLERKDKMG-GKRTVPWNCHTIQGRTFQDVATEISPEKAPLQPETSADFYRDWRRHLPSGPERYQALLQLGGPRLGCLFQTDVGFGLLGELLVALADHVGPADRAAVLGILCSLASTGRFTLNLSLLSRAERESCKGLFQKLQAMG-NPRSVKEGLSWEEQGLEEQSGGLQEEER-------LLQELLELYQVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGB6-1", "uniprot_id": "DAA19_DANRE", "id": "Q6DGB6-1", "name": "Dynein axonemal assembly factor 19", "aln": "ME--NSDVINFSCLEKELHSALQADRKYQRENDAKFRALNQKVASYEEFRDIVLASHLKPLDRNDISG-SPRKQPWNPVACRTNYVCASSEQVQPQLSEVQPRSASEFIRDWRRFAGCSFEKYSLLVSLGGEALQKIFSTEIGLGLLGEFLLILSQCLKSGDEDRVTGVLDGLSKTGRFSINLSLLSQAEQEACEELFNKLKVAAGECHPYKDNSNTSVVC----EAGLTHMEDNKTDITTTLKELAGKYGTEK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8J9-1", "uniprot_id": "A1Z8J9_DROME", "id": "A1Z8J9-1", "name": "Dynein attachment factor N-terminal domain-containing protein", "aln": "MDNWKITAEELIRLRESCLQCIRDGELYELRNDAKLRAVYS-TQNYEEFKNIVDAAHLRPVTKGDKANFKTKNRLWNSAARD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . :: *.:. .: .. *: .* **:**: . . .****:.** *:**:*: : * . : ** : ", "identical_positions": 21, "similar_positions": 27, "identity": "8.27%" }, { "cls_id": "homologset.agr.HGNC:32701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38889-1", "uniprot_id": "SKN7_YEAST", "id": "P38889-1", "name": "Transcription factor SKN7", "aln": "MSFSTINSNVNKTTGDSNNNTTENSSTADLLGMDLLQSGPRLMNTMQPNNSSDMLHINNKTNNVQQPAGNTNISSANAGAKAPANEFVRKLFRILENNEYPDIVTWTENGKSFVVLDTGKFTTHILPNHFKHSNFASFVRQLNKYDFHKVKRSPEERQRCKYGEQSWEFQHPEFRVHYGKGLDNIKRKIPAQRKVLLDESQKALLHFNSEGTNPNNPSGSLLNESTTELLLSNTVSKDAFGNLRRRVDKLQKELDMSKMESYATKVELQKLNSKYNTVIESLITFKTIN--ENLLNNFNTLCSTLANNGIEVPIFGDNGNRNPTGNTNPATTTAIQSNNNTNNASPATSTVSLQLPNLPDQNSLTPNAQNNTVTLRKGFHVLLVEDDAVSIQLCSKFLRKYGCTVQVVSDGLSAISTLEKYRYDLVLMDIVMPNLDGATATSIVRSFDNETPIIAMTGNIMNQDLITYLQHGMNDILAKPFTRDDLHSILIRYLKDRIPLCEQQLPPRNSSPQTHSNTNTANSNPNTINEQSLAMLPQDNPSTTTPVTPGASISSAQHVQQGQQEQQHQIFHAQQQQQHHNAIANARSDVAIPNLEHEINTVPHSSMGSTPQLPQSTLQENQLS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9UBD0-1", "uniprot_id": "HSFX1_HUMAN", "id": "Q9UBD0-1", "name": "Heat shock transcription factor, X-linked", "aln": "---------MEDKRSLSMARCEERNSRGQDHGLERVPFPPQLQ-------SETYLHPADPSP------------------------------------------AWDDPG------STGSPNLRLLTEEIAFQPLA--------------------------EEASFRRPHPDGDVPPQGEDNLLSLPFPQKLWRLVSSNQFSSIWWDDSGACR-------------------VINQKLFEKEILKRDVAHKVFATTSIKSFFRQLNLYGFRKRRQCTFRTFTRIFSAKRLVSILNKLEFYCHPYFQR--DSPHLLVRMKRRVGVKSAPR---------HQEEDKPEAAGSCLAPADTEQQDHTSPNEND---------------------QVTPQHREPAGPNTQIRSGSAPPATPVMVPDSAVASDNSPVTQPAGEWSE---GSQAHVTPVAAVPG------------------------------------PAALPFLYVPGSP------TQMNSYGPVVALPTASRSTLAMDTTGLPAPGMLPFCHLWVPVTLVAAGAAQPAASMVMFPHLPALHHHCPHSHRTSQYMPASDGPQAYPDYADQST---------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. . * . *..* .: *:: : *:* *. ** : : :* : * .**. . ::*.:.: .. :* * *:. **: * : :. :* : *:...* : : ::..*: .:.:. * : : * :* : :.::*: :::* :..: : .:.:: : : : .:**::: * . :. : * : . :*. :: * : :: .* :: .* .: :*: :** :: *: .:. . * ..*: *.. .. :.: :. : :.: * : * : **: *:.* :*: .* *: *: . * ...:*** . . *:. :. : . . * ::..: **:. . *:. :* : ::. .: ", "identical_positions": 64, "similar_positions": 171, "identity": "10.26%" }, { "cls_id": "homologset.agr.HGNC:32709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z9K4-1", "uniprot_id": "A1Z9K4_DROME", "id": "A1Z9K4-1", "name": "", "aln": "MTDGEQQEALVKRAEDEREDIFRRYELGLDPSNVVDSWENPTFEIYHRTDKYGFLHDSRLPSTRDAQEVHRNKIEMERDKKWMKMLNQWPPPQD--KLHKRVYKGIPDRVRMVAWNKLLDIQQSINNNAGVYLRMLQLARKYSTETRQIDADVNRQFRDNLAFRERYSVKQCSLFNVLNAYSIYNSELGYCQGMACVAGVLLLYLHEEEAFWALNTLITDQKYGMHGLFIEGFPKLTRFIDHHDRIMSKIMRKLHKHFTKHNVDALLYAIKWFFVVFVERVPFSLSLRVWDIFMLDGDRVILSMAITILYLHKDELLRLKDMDAIIEYLQVRLHKNFGYSDDDAIQALERVMKKLKDLKLDVPPPAKSNEFPTRKLGDFVEADMEKKIGRRRNDYTDAEKQVITDVISRQEQNAIDVQSTVSYETSECATGDGYSMKTFESITSLATSPANSSYSLYSNGFVVTTIDSEQDPARSQSIHNLSYLQTHPALPPNGLQHMRHSFSSDSDSRNRIDLDQALEVLQRQQLPLHPKTPSSQVVYIVQNGGGGGRYMDGHRDAADDDDDDALSVENTRL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A087WXS9-1", "uniprot_id": "TBC3I_HUMAN", "id": "A0A087WXS9-1", "name": "TBC1 domain family member 3I", "aln": "---MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELP-PLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCN-RFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSS--------ASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGG---------------AVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. . :*****: :** * .. *. :* . :..*: *::*::.** . *:*.:: : *:.*..**:.**.:* :. ** .*.***:* .:* *. **: :: :*.* * * : .:: * . ::** **. :*.:: **:**..** .*:::* **. **.*:***:.:: :*.::**** **:***** *::.:::.::*:. . .: : *:::::::. * * *::: . .: :: :::: :.:.*:**:**:::::*::.::.:: : :::..* : . .. .: : *: ..:. .:* .:: *. ****. : *:*****.:: .: *. .* : ..::*. .. :* : ..... : .:* ..*. : :.:*.: ::*. .:: . . : :: * : . * :* . ::.* ... * : ** * :: . : ::. : ::* : : .:.. .* :*.::: ", "identical_positions": 119, "similar_positions": 237, "identity": "20.62%" }, { "cls_id": "homologset.agr.HGNC:3271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1JU68-1", "uniprot_id": "EIF3A_RAT", "id": "Q1JU68-1", "name": "Eukaryotic translation initiation factor 3 subunit A", "aln": "MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSK--KHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQ--QVNIKSLEDVVRAYLKLAEEKTEAAKEES--QQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQS--TAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVR-FNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVAQIYQSIEFSRLTSLVPFVD-----AFQLERAIVDAARHCDLQVRIDHTSRTLSFGSD--------LNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVT------------AYIKNSRKEHQRILARRQTIEERKERLESLNIQREKEELE----------QREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRVKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERKITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGEDPLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRR-ETRDDERPHRRDEDRLRRLGGDDEERESSLRPDDDRIPRRGLDDDRGPRRGPDEDRFSRRGTDDDRPSWRNADDDRPPRRIGDDDRGSWRHTDDDRPPRRGLDDDRPPRRGLDDERGSWRTAEEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRR------------------------------GMDDDRGPRRGLDDDRGPWRNAAEDRISRRGADDDRGPWRNMDDD---------RVPRRGDDARPGPWRPFVKP--GGWREKEKAREESWGPPRESRPPEEREWDRDKEKDRDNQDREENDKDLERDRDRERDGDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRDRDDRRDLRDLRDRRDLRDDRDRRGPPLRSEREEASSWRR-TDDRKDDRTEERDPPRRVPPPTLSRERERERDRE--GEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23116-1", "uniprot_id": "EIF3A_MOUSE", "id": "P23116-1", "name": "Eukaryotic translation initiation factor 3 subunit A", "aln": "MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSK--KHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQ--QVNIKSLEDVVRAYLKLAEEKTEAAKEES--QQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQS--TAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVR-FSVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVAQIYQSIEFSRLTSLVPFVD-----AFQLERAIVDAARHCDLQVRIDHTSRTLSFGSD--------LNYATREDAPVGPHLQSMPSEQIRNQLTAMSSVLAKALEVIRPAHILQEKEEQHQLAVN------------AYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELE----------QREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRVKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHSRLEDRKRQRKEERKITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDDPLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRR-ETRDDERPHRRDEDRLRRLGGDDEERESSLRPDDDRIPRRGLDDDRGPRRGPDEDRFSRRGTDDDRPSWRNADDDRPPRRIGDDDRGSWRHTDDD----------RPPRRGLDDERGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRR------------------------------GMDDDRGPRRGLDDDRGPWRNAAEDRISRRGADDDRGPWRNMDDD---------RVPRRGDDARPGPWRPFVKP--GGWREKEKAREESWGPPRESRPSEEREWDRDKEKDRDNQDREENDKDLERDRDRERDGDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDREDRRRDRDDRRDLRDLRDRRDLRDDRDRRGPPLRSEREEASSWRR-TDDRKDDRTEERDPPRRVPPPALSRDRERERERE--GEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14152-1", "uniprot_id": "EIF3A_HUMAN", "id": "Q14152-1", "name": "Eukaryotic translation initiation factor 3 subunit A", "aln": "MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSK--KHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQ--QVNIKSLEDVVRAYLKMAEEKTEAAKEES--QQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQS--TAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVR-FNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVD-----AFQLERAIVDAARHCDLQVRIDHTSRTLSFGSD--------LNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVT------------AYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELE----------QREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLG-DDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDD----------RPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKP--GGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRR---DLRERRDLRDDRDRRGPPLRSEREEVSSWRR-ADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PCR7-1", "uniprot_id": "EIF3A_DANRE", "id": "Q6PCR7-1", "name": "Eukaryotic translation initiation factor 3 subunit A", "aln": "MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVIKSK--KHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQ--QVNIKSLEDVVRAYLKLAEEKTETAKEES--QQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSKVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLGQIQRHHNQS--TAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFALSKKPPKPQLMANYYNKVSTVFWKSGNALFHSCTLHRLYHLSREMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKHRRLATLLGLQSPPTRQSLINDMVR-FNLLQYVVPEVKELYNWLEVDFHPLKLCGRVTKVLNWVRDQAEKESDLQQYVPHLQNNTILRLLQQVAQIYQSIEFSRLASLVPFVD-----AFQLERSIVDAARHCDLQVRIDHSSRTLSFGSD--------LNYSTKEDSPVGPFLQNMPSEQIRNQLTAMSSSLAKAIQVIKPASILQDHEEQRQQAIT------------AYLKNARKEHQRILARRQTIEERKERLESLNIQREKEELE----------QREAELQKVRKAEEERLRQEAKEREKERIMQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKKAYEEQRIKDMELWELQEEERITNMKMEREKALEHKQRMSRMMEDKENFLSKIKAARSFIYEEKLKQFQERLVEERKKRLEERKKQRKEDRRKAFYHQKEEEAQRIREEQLKKEREERERLEQEQREEEEREYQERLRKLEEQERKQRARQQEIEERERRKEEERRAPEE---KPNKEWAEREESG-WRKRGEGESEWRRPVPDRDWRQEGREGREEPDREDRDLPFRRGGESARRG----ASDEKGLRRGCDDDRGPRRGGDDERPPRRGFDDDRGTRRGFDDDRGQRR-GDDDRG--------------------PRRGMDD----------DRGPRRPIDDDRGPRR------------SDDDRGPRR------------------------------GFDDDRGPRRGMDEPRGPRRGADDDWGPRRGGDDERGGRRGMDDS----------GPRRGEDSRP--WKPLGRPGAGGWREREKAREESWGPPRDSG------------HDDDGGERDGDDQR-EGERFRERRSAREEGSAWRRGGGGG--GGGEEQSSWRDS-RREDFDREDRRERR-------DMRERRDDRE-RDIRGP--QRDQDEGGSWRRGGEERREERKEERDAP--------PRPRERDRDSG-----EKSTWRSDKDKENPRRTKNETDDDGWTTVRR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN25-1", "uniprot_id": "EIF3A_DROME", "id": "Q9VN25-1", "name": "Eukaryotic translation initiation factor 3 subunit A", "aln": "MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQ--LVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQT--TGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVR-LNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPEN-ALLTPYIQSLKDVTIMRLIRQISQVYESIKFQRLLQLASFCN-----IFELEKLLVESVRHNDMQIRIDHQKNSIYFGTD--------LTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVN------------HYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEAR----------RQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVAQQERLKRMYPDRDEFLEALKKERASLYVEKLKKFEAALEAERKKRLADRIIRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLSRELASERERTEKDRDTWRPRGGDRPSASNG-GSSEWRRAAPAASERN--DRGGERIERGGER--IERGGERLERG------GERIER-GGDRDRKDNEGADSSWRVRREPDSQRAAAP-KDSGAPQSR--------------------------------------------DDKWRRGGERDRDFRIDGAR--------RDRDDGPRR--------------------------------DRDDGPRRDRDDERGGFRRADG--------------------------------ARRTDEPQR-----------------------------------------------------------------------------------------ETGGNWRDAPRHADRETRRPAERRD--------RDVRETRGDQRGSAPKEAASGGVGGNWRTAPATREEKPAAK-------------RDQAQEKENK------------------------AGDDGEWTSVKRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38249-1", "uniprot_id": "EIF3A_YEAST", "id": "P38249-1", "name": "Eukaryotic translation initiation factor 3 subunit A", "aln": "MAPPPFRPENAIKRADELISVGEKQAALQSLHDFITARR-IRWATPSTVEPVVFKFLEIGVELKKGKLLKDGLHQYKKLIQGSTEGLVSVGAVARKFIDLVESKIASEQTRADELQKQEIDDDLEGGVTPENLLISVYESDQSVAGFNDEAITSWLRFTWESYRAVLDLLRNNALLEITYSGVVKKTMHFCLKYQRKNEFKRLAEMLRQHLDAANYQQSKSGNNLVDLSDADTLQRYLDQRFQQVDVSVKLELWHEAYRSIEDVFHLMKISKRAPKPSTLANYYENLVKVFFVSGDPLLHTTAWKKFYKLYSTNPR-ATEEEFKTYSSTIFLSAISTQLD----------EIPSIGYDPHLRMYRLLNLDAKPTRKEMLQSIIEDESIYGKVDEELKELYDIIEVNFDVDTVKQQLENLLVKLSS----KTYFSQYIAPLRDVIMRRVFVAASQKFTTVSQSELYKLATLPAPLDLSAWDIEKSLLQAAVEDYVSITIDHESAKVTFAKDPFDIFASTASKEVSEEENTEPEVQEEKEETDEALGPQETEDGEEKEEESDPVIIRNSYIHNKLLELSNVLHDVDSFNNASYMEKVRIARETLIKKNKDDLEKISKIVDERVKRSQEQKQKHMEHAALHAEQDAEVRQQRILEEKAAIEAKLEEEAHRRLIEKKKREFEAIKEREITKMITEVNAKGHVYIDPNEAKSLDLDTIKQVIIAEVSKNKSELESRMEYAMKKLDHTERALRKVELPLLQKEVDKLQETDTANYEAMKKKIVDAAKAEYEARMADRKNLVMVYDDYLKFKEHVSGTKESELAAIRNQKKAELEAAKKARIEEVR-KRRYEEAIARRKEEIANAERQKRAQELAEATRKQREIEEAAAKKSTPYSFRAGNREPPSTPSTLPKATVSPDKAKLDMIAQKQREMEEAIEQRLAGRTAGGSSPATPATPATPATPTPSSGPKKMTMAEKLRAKR------LAKGGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *****:***:*::.**: **: * :.: : . **:::*:* : *:*:*.:: *:**.**::: * .: *: * * ::.:.*.: : : .: :**:. ***.:*:*. .::: : : .*::* **** *:*** *: * * .:.: :::***:* ** **::*.: ** ** .:: . :.:.. :: . *: *: :* ::.:***:**::::**:. *: :**:.* *. :****::: ** :*: *:*: : ::::* : *::::: :: ::*:::* : : : :: **.* *** ::..::. .: * :.::**: :**:*. .: :: .:: : . . : *: *:: : *:: :* : ::. ..* .*..: :::*: ::::. . :.: *** . .: *..* . * * :*. .* . : . . * :. . : :. * : :: :: :.: :: . : . . *.:*: . .:: * :: : *:: : *.* .* * : . ::::*: * . * :* : :.** : * ::.:: .**:.::: **:*: *** * *:**::. : : .* :* :: : * : : .::.: : * * :. : :: : * :: *: : :*: :. : ::: : * . : ... . :. . * : * . : :. . : . . . * : * :. . .* * ", "identical_positions": 165, "similar_positions": 329, "identity": "11.43%" }, { "cls_id": "homologset.agr.HGNC:3272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNA7-1", "uniprot_id": "EIF3I_RAT", "id": "B0BNA7-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDS----NEPYMKIPCND--SKITSAVWGPLGECIIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTSLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13347-1", "uniprot_id": "EIF3I_HUMAN", "id": "Q13347-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDN----NEPYMKIPCND--SKITSAVWGPLGECIIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZD9-1", "uniprot_id": "EIF3I_MOUSE", "id": "Q9QZD9-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDS----NEPYMKIPCND--SKITSAVWGPLGECVIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZV55-1", "uniprot_id": "EIF3I_DANRE", "id": "Q7ZV55-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFSVAKDPIANVWYSVNGERLGTYNGHTGAVWCVDVDWDTKNVLTGSADNSCRLWDCETGKQLALLETSSAVRTCGFDFSGNIIMFSTDKQMGYQCFLNYYDLRDP-QQIED----NQPYISVPCSE--SKITSAVWGPLGEFVIAGHENGEINQFSAKSGE-VLKKAKEHTKQINDIQSSVDLTMIISASKDCTAKMFDSSTLEHVKTFKTERPVNSAAISPIMDHVVMGGGQEAMEVTTTSTRIGKFEARFFHAAYEEEFGRVKGHFGPINCVAFHPDGKSYSSGGEDGYVRIHYFDPHYFDFELEA--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O02195-1", "uniprot_id": "EIF3I_DROME", "id": "O02195-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MRPLMLQGHERSITQIKYNREGDLLFSCSKDQKPNVWYSLNGERLGTYDGHQGAVWCLDVDWESRKLITGAGDMTAKIWDVEYGTVIASIPTKSSVRTSNFSFSGNQAAYSTDKAMGQSCELFLIDVRNADSSLSE----QEPTLRIPMTE--SKITSMLWGPLDETIITGHDNGNIAIWDIRKGQKVVDSGTDHSAGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPIMDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVQTFDSTYFENIFE---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40217-1", "uniprot_id": "EIF3I_YEAST", "id": "P40217-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKAIKLTGHERPLTQVKYNKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVMKNPGSINIYEIERDSATHELTKVSEEPIHKIITHEGLDAATVAGWSTKGKYIIAGHKDGKISKYDVSNNYEYVDSIDLHEKSISDMQFSPDLTYFITSSRDTNSFLVDVSTLQVLKKYETDCPLNTAVITPLKEFIILGGGQEAKDVTTTSANEGKFEARFYHKIFEEEIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIRLHHFEKSYFDFKYDVEKAAEAKEHMQEAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: * ****.:**:***:******: :** .****:******* ** *::*.:*.* :: :**:.* : ::** . * :* : .*: *. ** *: * : ::. . ::* : : . * *.. .: :*:**..*:: :. .. : . * *.*:* * * * ::::*:* .: :.* :* *.:.*: *:*:*.::* :.:::****:* :*****:. ***::**:* :***:.*::*****:* :*: *:*.**:******::*:: *: **: : ", "identical_positions": 114, "similar_positions": 108, "identity": "32.85%" }, { "cls_id": "homologset.agr.HGNC:3273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P9U8-1", "uniprot_id": "EIF3H_RAT", "id": "Q6P9U8-1", "name": "Eukaryotic translation initiation factor 3 subunit H", "aln": "MASRKEGTGSTATSSSSTGGAVGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKANITFEHMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIIKYNTYMRNSSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPHQAPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYSN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WK2-1", "uniprot_id": "EIF3H_MOUSE", "id": "Q91WK2-1", "name": "Eukaryotic translation initiation factor 3 subunit H", "aln": "MASRKEGTGSTATSSGSAGGAVGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKASITFEHMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKSLQLLMDRVDEMSQDIIKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPHQAPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15372-1", "uniprot_id": "EIF3H_HUMAN", "id": "O15372-1", "name": "Eukaryotic translation initiation factor 3 subunit H", "aln": "MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AXJ2-1", "uniprot_id": "EI3HA_DANRE", "id": "Q6AXJ2-1", "name": "Eukaryotic translation initiation factor 3 subunit H-A", "aln": "MASRKESAASGS-----------------NPLDFPVKQIQVDGLVVLKIIKHYQEEGQGSEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDVEFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVSRALLDSQFSYQHAIEESVVLIYDPLKTAQGSLCLKAYRLTPKLMEICKEKDFTPEGLKKAAVAYEHMFEEVPIFIKNSHLINVLMWDLQEKSTLADKHELLNLSSSNHLEKSLQLLMDRVDDMSQDIVKYNTYCRNLSKQQQQKQQYQQRRQQENAQRQSRGEPPLPEEDISKMFKAPQAPPRMDTLLIAGQINNYCQNIKEFTSQNLGKLFMAEALQSNSS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5PR67-1", "uniprot_id": "EI3HB_DANRE", "id": "Q5PR67-1", "name": "Eukaryotic translation initiation factor 3 subunit H-B", "aln": "MASRKETPNG-------------------KTLDTPVKQIQIEGLVVMKIIKHYQEEGQGSEVVQGVLLGLVVEDQLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTLYGSFVSRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLCLKAYRLTPKLMEICKEKDFSSEGLKKASVGYEHMFEEVPIVIKNSHLINVLLWELEEKSTAADKHELLSLSSSSHLEKSLQMLMDRVDDMSQDIVKYNNYSRSLSKQQQQKHQYVQRRQQENAQRQSRGEPPLPEEDLTKMFKPPQPPPRMDTLLIASQINTYCQTIKEFTSQNLGKLFMAEALQGPSS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U9Q4-1", "uniprot_id": "EIF3H_DROME", "id": "Q9U9Q4-1", "name": "Eukaryotic translation initiation factor 3 subunit H", "aln": "MANRANRHAART-----------------EDSDNTINYVQCDGLAVMKMVKHCHEESSNMDLAQGALLGLVVDKCLEITNCFPFPKS--GDETMDEEMYQLTVMRRLRRVNVDHLHVGWYQSSDVGNSLSMALLESQYHYQTSIEESVVVVYDTQKSSRGFLCLKAYRLTPQAIQMYKDGDFTPEAFRTLKVGYENLFAEIPIVIKNSPLTNIMMSELNELLPEDKGHNFLDLGTATVLENQMRSLIERVDELYQEAVRYNKYQQVVFKQDTEKHRALAKLAAENAVRTSKGEPTVPEEEVIKQFRPMTAPNRLTATITSGQINTHAQHIAQFCSQSLAKLFITESLQIAKEAKETK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* : . * .:: :* :**.*:*::** :**... ::.**.******:. **********: .* :** **: :** **:**:**********: *. :: ***:**: ** :******::**. *:::* *.********: ::: *: **:.*.::. : :* :* *:**.**** * *::: :*:: . . *::*.*.::. * :.:: *::***:: *: ::**.* : **: :*:: : ** * *:***.:***:: * *:. .* *: : : :.***.:.* * :* :*.*.***::::** .. ", "identical_positions": 137, "similar_positions": 118, "identity": "38.38%" }, { "cls_id": "homologset.agr.HGNC:3274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1D1-1", "uniprot_id": "EIF3G_MOUSE", "id": "Q9Z1D1-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPTGDFD-SKPSWADQVEEEGEDDKCVTSELLKGIPLPTGDTSPEPELLPGDPLPPPKEVINGNIKTVTEYKIEEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQE-EEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQAAQSKTGKYVPPSLRDGAS-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RK09-1", "uniprot_id": "EIF3G_RAT", "id": "Q5RK09-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPTGDFD-SKPSWADQVEEEGEDDKCVTSELLKGIPLPTGDTSPEPELLPGDPLPPPKEVINGNIKTVTEYKVEEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQE-EEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQAAQNKTGKYVPPSLRDGAS-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75821-1", "uniprot_id": "EIF3G_HUMAN", "id": "O75821-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPTGDFD-SKPSWADQVEEEGEDDKCVTSELLKGIPLATGDTSPEPELLPGAPLPPPKEVINGNIKTVTEYKIDEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQE-EEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQATQNKTGKYVPPSLRDGAS-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRC4-1", "uniprot_id": "EIF3G_DANRE", "id": "Q6DRC4-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPSIEFDDSKPSWADQVEEEGDE----------------------------GSLPSPKETVKGNIKTVTEYKIDDDGQKFKIIRTFKIETRKASKAVARRKNWKKFGNSEYDAPGPNVATTTVSDDVFMTFISSKEDLNAQDQDEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEK-AAEPEPAQPVQNKTGKYVPPSLRDGGT-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKNTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSNN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4X7-1", "uniprot_id": "EI3G1_DROME", "id": "Q9W4X7-1", "name": "Eukaryotic translation initiation factor 3 subunit G-1", "aln": "--MPGVETIKSSWADEVELDYG------------------------------GLPPTTETVENGQKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGDSKNDKPGPNSQTTMVSEEIIMQFLNSKEDEKANDPLLDPT-----KNIAKCRICNGEHWSVNCPYKGTA----------MDTN-MMEKKASAAAAAAVDAP-KSGKYVPPFLKD----SQKGALG-MRGRDDTAAIRISNLSESMTEADL-EELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSKPQNN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDM6-1", "uniprot_id": "EI3G2_DROME", "id": "Q9VDM6-1", "name": "Eukaryotic translation initiation factor 3 subunit G-2", "aln": "-----MKTFVTSWADEVDADYVD-----------------------------GLPPSNEYIKGDFKYVTEYKFNDDGKKVKVVRTFKIEKQIVPKAVARRRNWVKFGDSRSDKPGPNSQTTMASEEIFMQFIGSKDFDQTHETQLDPG-----KNIAKCRICNGEHWSVNCPYKGTS----------MDSKTVMETKANAAAAAAISDPSKTGKYVPPFMKDGGGISGSKNWGRGRDRDDSSAVRISNLSESMTETDL-EELVKKIGPHTKMYLAREKNSGLCKGFAYVHFKFRQDAAAAIEVLNGHGYDHLILCVEWSKPQP--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04067-1", "uniprot_id": "EIF3G_YEAST", "id": "Q04067-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "----MSEVAPEEIIENAD-------------------------------------GSRSIITYKIEDGVKYKITQKVKEVKVL-------EKVHKSVAERKNWHKYGSEKGSPAGPSAVTARLGEEVELRLS--RNWKQAEEERIQKEKASLTKTGLQCRLCGNDHMTMNCPFKTILSELS-ALEDPATNEGGVEAASEEKAGQVGGAGSIPGQYVPPSRRAGARDPSSDAYRDSRERDDMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::.: . . : : .:** .. :: *:: . . *:**.*:.* *:*... . .**. *: .::: : : :: : .: : :. .**:* .:* : .**:* . : . .*:**** : * ** .:::: ::.*. * .* :**. :.. .:: :.::* :* .:*:*:: * .: * *: :.* ** :*** ***:**. ", "identical_positions": 51, "similar_positions": 95, "identity": "15.69%" }, { "cls_id": "homologset.agr.HGNC:3275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AC36-1", "uniprot_id": "D4AC36_RAT", "id": "D4AC36-1", "name": "Eukaryotic translation initiation factor 3 subunit F", "aln": "MASPAVPASVPPATAAAAPAPAVTSAPASAPTPPTPAPAQAATPAAAPAPVSS-DPAVATPAAPGQTSTSTPAPAQTPAPSQPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDE--VAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPN--PIHLTVDTGLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTC-FSPNR---VIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCH4-1", "uniprot_id": "EIF3F_MOUSE", "id": "Q9DCH4-1", "name": "Eukaryotic translation initiation factor 3 subunit F", "aln": "MASPAVPANVPPATAAAAPAPVVTAAPASAPTPSTPAPTPAATPAASPAPVSS-DPAVAAPAAPGQTPASAPAPAQTPAPSQPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDE--VAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPN--PIHLTVDTGLQHGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTC-FSPNR---VIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00303-1", "uniprot_id": "EIF3F_HUMAN", "id": "O00303-1", "name": "Eukaryotic translation initiation factor 3 subunit F", "aln": "MATPAVPVSAPPAT----PTPVPAAAPASVPAP-TPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDE--VAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPN--PIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTC-FSPNR---VIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NXK7-1", "uniprot_id": "A0A8M1NXK7_DANRE", "id": "A0A8M1NXK7-1", "name": "Eukaryotic translation initiation factor 3 subunit F", "aln": "------------------------------------------------------------------------------------MAVHGP-----VVKIHPVVLASIVDSYERRNEGASRVIGTLLGTADKHSVDVTNCFSVPHNESEDE--VAVDMEFAKNMYELHKKVSPSEVIVGWYATGFDITEHSVLIHEYYSREAPN--PIHLTVDTALQSNKMNIRAYVSSQMGVPGKTVGVMFTPLSVKYIYYDTERIGVDLLQRTR-ASPGR---TNGLTTDLAQVAGAAGRVQEMLATVLSYIEDVLSGKVMADNSVGRFLMDLVNKVPKIPAEDFENMLNSNINDLLMVTYLANLTQAQIALNEKLVVL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN50-1", "uniprot_id": "EI3F1_DROME", "id": "Q9VN50-1", "name": "Eukaryotic translation initiation factor 3 subunit F-1", "aln": "-----------------------------------------------------------------------------------MSALNLT------VRVHPVVLFQVVDAFERRNADSHRVIGTLLGSVDKGVVEVTNCFCVPHKEHDDQ--VEAELSYALDMYDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYARECNN--PVHLTVDTSLQGGRMGLRAYVCIQLGVPGGKSGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPAHRPKTVPPMLDLAQISEASTKLQSLLDLILKYVDDVIAHKVTPDNAVGRQLLDLIHSVPHMTHEQFTQMFNANVRNLLLVITLSQLIKTQLQLNEKLTFLPTA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z6K7-1", "uniprot_id": "EI3F2_DROME", "id": "A1Z6K7-1", "name": "Eukaryotic translation initiation factor 3 subunit F-2", "aln": "-------------------------------------------------------------------------------------MMSRNFSMRAKVYLKPLVFFQIIDAYDRRPKGDNQVMGTLLGRNKEGHIEITNCFTVPHKEHSENKRIDLDMAYASEVLELNMFAYPNERVLGWFCTGKSVSRSASLIHDYYVRECCEGQPLHLLVDAALKNQRLSTRLYCAVEMGVPGGTKGLMFSLVPLEISNENSDLVALRCIEKQSQQQASK--QMERFVPELAQVVDATRDMQHRLDLVLRYINDVLARKKKPDNVVGRSLYAALTAVPLLDSDKFRVMFNTNLRDMLMAITLSTMIKTQLEISEKLSCMQDQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::*::: .::*:::** . :*:***** .: :::**** ***:* .:: : :: :* :: :*: . ..* ::**:.** .::. : :**:** **. : *:** **:.*: ::. : * . :**** . * **: :.:: :.: ..: : : .. : :* *: *: :* * :* * :**:: * .** *** * : ** : :.* *:*:*:.::*:. *: : ::*: :.*** : ", "identical_positions": 74, "similar_positions": 104, "identity": "19.84%" }, { "cls_id": "homologset.agr.HGNC:3277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60228-1", "uniprot_id": "EIF3E_HUMAN", "id": "P60228-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSD-DIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60229-1", "uniprot_id": "EIF3E_MOUSE", "id": "P60229-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSD-DIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q641X8-1", "uniprot_id": "EIF3E_RAT", "id": "Q641X8-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSD-DIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DRI1-1", "uniprot_id": "EI3EA_DANRE", "id": "Q6DRI1-1", "name": "Eukaryotic translation initiation factor 3 subunit E-A", "aln": "MAEYDLTTKIAHFLDRHLVFPLLEFLSVKEIYNEHELLHGKLDLLSDTNMVDFAMDVYRNLFPDKEIPNSLREKRTTVVAQLKQLQSETEPIVKVFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALNSLWGKLASEILMQNWEAAMEDLTRLRETIDNNTVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIELFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDSAQKKLRECEAVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISIGMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAISPYQQVIEKTKSLSFRSQMLAMNIEKKQSNANRNETPNWAAQDAGFY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LUA8-1", "uniprot_id": "EI3EB_DANRE", "id": "Q1LUA8-1", "name": "Eukaryotic translation initiation factor 3 subunit E-B", "aln": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSETNMVDFAMDVYKNLYPDKEIPHSLRDKRTTVVAQLKQLQSETEPIVKMFEDPETQRQMQSTRDGRMLFEYLADKHSFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPSTDRNALSSLWGKLASEILMQNWEAAMEDLTRLRETIDNNTVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIELFLYQPQYLNAIQTMCPHILRYLSTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDSAQRKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISISMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKISHSNRNETPNWAAQDTGFY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O77410-1", "uniprot_id": "EIF3E_DROME", "id": "O77410-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MANFDLTRINCQFLDRHLTFPLLEFLCGKEIYNQQELLEYILETVNKTNMIDYTMDTRKRLNLSQEMPEELVQRKAEVLATLKQLQNEVAPIMKAT---DILKNGESMKDSKTFVNALQKDYNFKVEHLESAYKLAKYLYECGNYQESTSYLYFCLIVMSPNDKNYLNVLWGKLAAEILTLNWNTALEDLTRLRDYIDNANFST-IQALQQRTWLIHWSVLVFFNHPKGRDLIIEMFLYKPLYLNAIQTMCPHIMRYLATAVVIN---RTRRNALKDLIKVIQQESYTYRDPITEFLECLYVNFDFEGARLKLHECQTVILNDFFIVACLNEFVEDARLMIFETFCRIHQCITISMLADKLNMKPNEAECWIVNLIRNARLNAKIDSKLGHVVMGTQPLSPYQQLVEKIDSLSMRSEHLAGLIERKSKQKQNQES----ADSWKYY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*** .:******.*******. *****::***. *: :..***:*::**. :.* . ::*. * :::: *:* ***** *. **:* : :: :* :*.: :.: * ..:.*: *:*:: *: **: ******. ::.**** :::...*:* *. ******:*** **::*:******:: *** ..*: :*:***********::********** **::***:* ************:***:***: * *.**:.****:**********:******:*********:.*: **:**::*::****:****::*:*:***:************:*.********.*:*** ***********:*************.:.:*****::** .***:**: ** **:* .: ...*: ::. :*", "identical_positions": 257, "similar_positions": 126, "identity": "57.62%" }, { "cls_id": "homologset.agr.HGNC:3278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYK8-1", "uniprot_id": "EIF3D_RAT", "id": "Q6AYK8-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDETSFQLVDTARTQKT-AYQRNRMRFAQRNLRRDKDRRNMVQFN---LQTLPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQ---KPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGRE--RYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSEEDEEDEEEEE---EEEEEEET--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70194-1", "uniprot_id": "EIF3D_MOUSE", "id": "O70194-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDETSFQLVDTARTQKT-AYQRNRMRFAQRNLRRDKDRRNMVQFN---LQTLPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQ---KPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGRE--RYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSEEDEEDEEEEE---EEEEEEET--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15371-1", "uniprot_id": "EIF3D_HUMAN", "id": "O15371-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDESSFQLVDTARTQKT-AYQRNRMRFAQRNLRRDKDRRNMLQFN---LQILPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQ---KPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGKE--RYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDEEEEEEEE---EEEEEEET--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TH15-1", "uniprot_id": "EIF3D_DANRE", "id": "Q6TH15-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFHAPVIQDNPSGWGPCAVPEKFKDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDEASFQLVDTAKTQKT-AYQRNRMRFAQRNLRRDKDRRTLTQFN---MQTLPKSAKQKERDRMRLQKKFQKQFGVRQKWDQKSQAQLKPRDSSVEVRSDWEVKEEMDFPRLMKMRYMDVADPLDIECCGALEHYDKAFDRITTRNEKPLKSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMCCTRSVNSWDIIVQRVGNKLFFDKRDNSDFDLLTVSETANEPPQDEGSSLNSPRNLAMEATYINHNFSQQCLRMGGE--RYKFPNPNPFVEEDTEKSEVASVAYRYRRWKLGEDIDLIVRCEHDGVMTGANGEVSFINVKTLNEWDSRYCNGVDWRQKLDSQRGAVLATELKNNSYKLARWTCCAILAGSEYLKLGYVSRYHVKDSSRHVVLGTQQFKPNEFASQINLSMENAWGILRCVIDICRKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDEEEDDEDE---EDEEEDEDN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGC7-1", "uniprot_id": "EI3D2_DROME", "id": "Q9VGC7-1", "name": "Eukaryotic translation initiation factor 3 subunit D-2", "aln": "-------MSNYAPFIKPYVEYNEHGWGPCEVPE--LDVPYQPFCKSDRLGKICDWTAMVP-EKKFPSKYASTFGNNSQYAYFYEDDDSTFHLVDTTGSKATKPYQRGRYRPNMRNNVRSRGRTGRGTPNIASLGGSTAGGATASTTKYGKGRNTRNTQNMGRRFG-RNAPT-RIRESSVMVQSDWVSIEEIDFPRLLKLALPNIKDGKDIATCGWLEFYDKLYDRVNLRNEKPLQKMDRVVHTVTTTDDPVIRRLSRTMGNVFATDEILSTIMCCTRSNYSWDVVVEKLGTKVFLDKRYNDQFDLLTVNETSVEPPMDEEGSINSAHSLAMEATLINHNFSQQVLRIGDQEPRFMFEEPNPFE--EPGVD-LASIGYRYRQWDLGNDVVLIARCKHNGVIQGPNGDVQFLSIKALNEWDSKVTNSVEWRQKLDTQRGAVLASELRNNACKLARWTVEAVLAGSDQLKLGYVSRMNPRDHLRHVILGTQQFKPQEFATQINLNMDNAWGVLRCLIDLVMRQPDGKYLIMKDPNKPMIRLYDVPENAFDSDGDEEEESSD----PLSNSNDN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCK0-1", "uniprot_id": "EI3D1_DROME", "id": "Q9VCK0-1", "name": "Eukaryotic translation initiation factor 3 subunit D-1", "aln": "MSETINTAAQFPSFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTNTSNNDKKYQNKYASSFGTGIQYSYYHEEDETTFHLVDTARVQKP-PHQRGRFR-NMRNSRSGRGRNAR--------GGLNTHGMTTLSGKNVKARDPRHGRGMGKKFGHRGPPP-KMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGVDIVTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCSTRSNYSWDIVIEKVGDKVFMDKRDHTEFDLLTVNESSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEPKYKFEESNPFISEDEDIQ-VASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFMTIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDEGFQQVYNYAHNKI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :: * ***** :*: *:*****.*.*****:.*** :*:: .**:* ** . **:*::*:*:::*:****: : . .:**.* * ** .:.* . : :. :: .: :::. :. : *:*** *::** **:***:*:*: :: : ** ** **.*** :**:. :.****:.:.*:.************:*::* ******* **:*:*..*** ***::::::* *:*:*** : :******.*:: *** *: .* **.:.**:*** ******** *: * : :: * :.*** : . :**:.***::*.**.*: *:.**:*:**: ..*: .*:.:*:******: *.*:******:*****:*.**:**: ***:** *:****: ******** : :* ***:********:***:****.::****:***:**: : :*****:***** :**:*.:*:.:*.*: .:: : .: : . ", "identical_positions": 251, "similar_positions": 167, "identity": "43.88%" }, { "cls_id": "homologset.agr.HGNC:32789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB94-1", "uniprot_id": "GFRAL_RAT", "id": "D3ZB94-1", "name": "GDNF family receptor alpha-like", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MLVFIFLAVRLSSENESSSQTNDCAYF-------------------------MRQCLTDTDGCKQS------WRSMEDACLVS--GDSCKINNPLPCNLSIQSLVEKHFQFKGCLCTDDLHCTVNKIFG------------------------------------KKCTNKTDSMKKDNKYKRNLTT-PLYHDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFKQMQSCLEVTEACVGDVVCNAQLALYLKACTANGNLCDVKHCQAAIRFFYQNMPFNTAQMLAFCDCAQSDIPCQQSKETLHSKPCALNVVPPP-TCLSVIHTCRNDELCRTYYRTFQTECWPHVAGKCREDETCISMLGKQDLTCSGS----------DSCRAAYLGTFGTVLQVPCACRSITQGEEPLCMAFQHMLHSKSCFN-----------------------------------------YPTP-NVKDISSYE------RKHSKEITLTGFNSP-------------------------------------------------------FSG--------------------ELIYVVVCMVVTSGILSLVMLKLR---IPSKK-----RDPAPIEIAGAVIIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6SJE0-1", "uniprot_id": "GFRAL_MOUSE", "id": "Q6SJE0-1", "name": "GDNF family receptor alpha-like", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MLVFIFLAVTLSSENESSSQTNDCAHL-------------------------IQKCLIDANGCEQS------WRSMEDTCLTP--GDSCKINNSLHCNLSIQALVEKNFQFKECLCMDDLHCTVNKLFG------------------------------------KKCTNKTDNMEKDNKDKWNLTTTPFYH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFKQMQSCLEVTEACVGDVVCNAQLALYLKACSANGNLCDVKHCQAAIRFFYQNMPFNTAQMLAFCDCAQSDIPCQQSKETLHSKPCALNIVPPP-TCLSVIHTCRNDELCRTHYRTFQTECWPHITGKCHEDETCISMLGKQDLTCSGS----------ESCRAAFLGTFGTVLQVPCACRGVTQAEEHVCMIFQHMLHSKSCFN-----------------------------------------YPTP-NVKDISSYE------KKNSKEITLTGFNSF-------------------------------------------------------FNG--------------------ELLYVVVCMAVTCGILFLVMLKLR---IQSEK-----RDPSSIEIAGGVIIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXV0-1", "uniprot_id": "GFRAL_HUMAN", "id": "Q6UXV0-1", "name": "GDNF family receptor alpha-like", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MIVFIFLAMGLSLENEYTSQTNNCTYL-------------------------REQCLRDANGCKHA------WRVMEDACNDSDPGDPCKMRNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKLLG------------------------------------KKCINKSDNVKED-KFKWNLTT-RSHH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPP-TCLSVIRSCQNDELCRRHYRTFQSKCWQRVTRKCHEDENCISTLSKQDLTCSGS----------DDCKAAYIDILGTVLQVQCTCRTITQSEESLCKIFQHMLHRKSCFN-----------------------------------------YPTLSNVKGMALYT------RKHANKITLTGFHSP-------------------------------------------------------FNG--------------------EVIYAAMCMTVTCGILLLVMVKLRTSRISSKA-----RDPSSIQIPGEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UV70-1", "uniprot_id": "A0A8N7UV70_DANRE", "id": "A0A8N7UV70-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------MRATRAAILLASHLLFGLVCIDASRSTDCISH-------------------------MAACVS-PHVCKSQ------QSTLRQTCQFK--DGTCRMTNAERCSGSLQMMLEGSPALRGCVCSLTDPCRTLQQLY------------------------------------SHCQPHWALKNKHLEASDHKAH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALHADRPCLEEIAACLGEESCNRPMVPLLQECKAS----SCNQCTEAIRQFYSALPHSVAETLVFCECGAQDQQCQEMKALIHYGSCVSEQTQTPWTCLEALDSCFEDASCRQVFDGFLSKCFEAEESAFDSTSDWLYLLDP-DFFLGED----------VECRAAFVETVGSVLHHPCTCAGLHHHHQYKCDELKLIFQDKSLFKRSRRKDSLL------------------------------HGKPHEPNTQQQPSNEPSPDQQRIDGANLIHGQSNDS-------------------------------------------------------SNGQQATNESHVQQKLLSDQLLYLLIYISALMVLVLFIVSLVLHRVRRIHQAAGKPTFEDQQSKSLMMLSSVII------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7J4-1", "uniprot_id": "A0A0B4K7J4_DROME", "id": "A0A0B4K7J4-1", "name": "", "aln": "MTRFRIKNLKILSCCLSLWVVLFGGALHLAQGSEFPERECCDLTTTSTVGPLPMPPAALPTDKSLSSATTALETDLAIGRSGSTIKGVVAILNCILARQLCFEDPSCSAILEIIPRVCGPIPVSCSTVTVTKCQAALRTLQAFQFFRPTCLCKEPGMDPDCNHFRDFLFDHPCGFVLKKAEKDPYPIDALPTCNHALSVCQQERKCLKLFEDFKTHCKVR--DNKCKMENRDACHDSWTNLRLS--PMFGCICPNNHMKKRCDRIFNIVNHNPCVDRLIFFPNGLPKLKQPRPKAKPRPKPKPKSKPKPRQRHHGMNGTELMTNNIEYHDEPNGLSDPEDEANETVDEDPGGHGDEDEDEEDDDYDDRIRAEIYSNYPHYLHPPSWGINNPLVLASHSPHTLDDDDDVVVEVVANKKPPPVTLHHHNDELDHDVVVVVDAGPHSHSHPHSHTFYSHGDQSSTTGSGLPGPAPTIPSPPNTGTKMHKTAPLGDLVAGSDITHRTYTGPSMDERVRILGMDEKLHQRIFNDNLALIDTPLIAMGSGSGSGTVTTSVSGYGLGMGMGLSGSFNYLGSMHGVPSYPFNISGFHQRHMAAAAADNEPFDIIDTGLGYGGNGNAGVYYQSGQDVEVDLSTEIIKQHFQSTCHTALDTCREDPSCSSSLQPMLTHCELHR--CNRNACMSSLQAFYKGPHEDLNLDIAFCLCKKTS--SQQNGNGNRHDMCMIAQEKLHPVCAQRPPDNSNPASSNGIYYHPPPACHVVAD-SCKEDRECRLKLEYYEQACAVDSVTKKCAGRPSGCRTAMIGILGTMLRTTCACQGTDPQHLYQCVGWRRLLWMNPCVVEAQKDFHMKRLAELGFLTTTTTTTTTTTTTTTTTTTRAPPPPPPPTTTTTTTTSMQPRQTPRKPATHIFKDVITAKEKSEPTSVEHNYLDPPDSIPLPSVNVESGGNGGNDDYHNGNGNGHGNGNGNGRRKNGGKGRGGSVDFDDPVIFVDPRETTEFVGISITEPVTTTTTTMATTTTTQPPRNCVVQRPRQSDQLIREGSSKRIYSLDDVECSELCSCGESLILTCHALCVPFAPCRTALAFYSHASPAYQAFRGRCLCYSGRFICMKPPLGEYILPGGIFLLLGYSAADEALLRPHTNLGVQDAVRALQQYVTTYIDNQTQCTLTLFNMTEENIIIAARLPHDGKLKDIELLRKEKDECTAILKTISHQINSEHSELQSHRLLSIFKMSEVEVVWPESTSAAARSGHGPGQFAGCDRLLYAAMLALAYLSSWTTLRMSDVAT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. :* * *: :. * .. *:: * * * : : *:* . : :. : .. : . : : .* :* : *. : * * . : * ::: **. . :.** * . .*: : * .* . : .. : . * . * : . . *::* : .*::*: *:* . * : :: :. . * .. . : . .: .* : :. .: ::. : . ", "identical_positions": 35, "similar_positions": 88, "identity": "2.72%" }, { "cls_id": "homologset.agr.HGNC:3279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFC8-1", "uniprot_id": "EIF3C_RAT", "id": "B5DFC8-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYVRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDDDGVSGTAFLKKKPDS----SGESRKFHKKMEDDDEDSEDSEDEE-WDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRMDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIASENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILE-----ESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----ICQIYLRRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1B4-1", "uniprot_id": "EIF3C_MOUSE", "id": "Q8R1B4-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVGNTTFLKKKQES----SGESRKFHKKMEDDDEDSEDSEDEE-WDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIAAENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILE-----ESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----ICQIYLRRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99613-1", "uniprot_id": "EIF3C_HUMAN", "id": "Q99613-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAP---SGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILE-----ESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----VCRIYLLRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFQ2-1", "uniprot_id": "EIF3C_DANRE", "id": "Q6PFQ2-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFATGSDSESEESSSADEITPKAAGTTLRQQALLLSDDEEDTKRVVRSAKDKRFEELTNLIKTIRNAIKIRGISKCLEEFEQLCRAFVKSKTIVDKEG---VPKFYIRLLADLEDYLNQLWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFETEIASYKENPEQSADEEEEKDDIGSGSSESDDDDDDDITAKSFMKKKPQEEEKKAPEASKFLKGAADEESESDDDEDSEDWASDSVGSDSESEDNDGTAASLAVVFLKKDVGEKASDRKKDDRR--RRHKKKERIEEEAEEEGEAEEGG-WEKVKGGVPLVKEKPKMFAKGTEINTGVVVKKLSEILQARGKKGTDRAAQIELLHALAGIAAENNLGEGILVKIKFNIIASLYDYNPNLAAFMKADMWKKCLDCIDELLDILFNNNNIFIGENIAE-----DSENLAISDQPFRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVDNLKDEGRVCGIIDRLLQYLETKGSTEE-----VCRVYLRRIMHTYYKFD-----YKAHRRSLG-LQGETKSEQDQEESEGDDSAIIMDRLCKFIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGMIKDAHNALLDIQSSGRAKELLGQGLLMRNMQERNAEQEKIEKRRQ-VPFHMHINLELLECVYLVSAMLLEIPYMAAHEFDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWRTCHSFIINEKMNSKVWDLFPEAKCVREMLVRKIQEESLRTYLFTYSSVYDSISMETLSEMFELELPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTSLQNMALQLAEKLGGLVENNERVFDLKQG---------------------VYGGYFN---RDQKGGYQQKQGYQRGDQKGGYQQKQNYQRGGYRNQNQSSY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAX1-1", "uniprot_id": "EIF3C_DROME", "id": "A1ZAX1-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFANGSESESES--SEEEIQATNFN---KASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVALESDGGDAGDDSDAGVKPTEAVPKAVKS------------APAKAAPADDDDSDDSIDWDSDSE-SETESSDDENQYQNMRERFLKRTTEKEEKD---DDKRKDKRKEQKTKIRKRAE----DDEDGEWETVVKGH--VVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQKISEPMKLEHWALLLEVMQSMMKLLLANADIIMSESVAE-----EHEEYATS--PFYVRGCPLAAVERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNE-----RCRIYLRKIEHLYYKFD-----PEVLKKKRGELPATTSTSVD-----------VMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQGNVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQ-MPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMIS---KTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVGMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWLGQRRDRNNRNRNQRGHHKNNQDRQQQQQQ---------QVQTIDEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32497-1", "uniprot_id": "EIF3C_YEAST", "id": "P32497-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFSSNYEYDVASSSSEEDLLSSSEEDLLSSSSSESELDQESDDSFFNESESE----------------SEADVDSDDSDAKPYGPDWFKKSEFRKQGG-------------GSNKFLKSSNYDSSDEESDEEDGKKVVKSAKEKLLDEMQDVYNKISQAENSDDWLTISN-----------------EFDLISRLLVRAQQQN------------------------------WGTPNIFIKVVAQVEDAVNNTQQADLKNKAVARAYNTTKQRVKKVSRENEDSMAKFRNDPESFDKEPTADLDISANGFTISSSQ-----GNDQAVQEDFFTRLQTIIDSRGKKTVNQQSLISTLEELLTVAEKP----YEFIMAYLTLIPSRFDASANLS-YQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIEDEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQFKSKFTSKDQLDSADYVDNLIDGLS-TILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEECHQILNDLLSSSHLREILGQQSLHRISLNSSNNASADERARQCLPYHQHINLDLIDVVFLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAKSMQKGNWRDSVKYLR----EIKSWALLPNMETVLNSLTERVQVESLKTYFFSFKRFYSSFSVAKLAELFDLPENKVVEVLQSVIAELEIPAKLNDEKTIFVVEKGDEITKLEEAMVKLNKEYKIAKERLNPPSNRR---------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.. : : . * ::: .. .. . *:*. . ....::.: . .: . .. : : * . .: :.:::. * ...:. .::. * : : ::*: . :*. .:: .: : : : : .: : . * : . . :. :: : :: . :: : ::. .. : . : * .: . : .. :* *:. **** .:: *. * * :: : : :.:*.: :* . ::: : * :: :..::. * : :.. : : * : *. :: ***:*:** * : : ****.:*: .*:** : * *:* . . :. : :: :: * *** : :. . :. . ::: *. * :*: . ::. *** :**: *::. : *:*::* *::* **: *.. :**:** :.:**:.**: ::.*: * *: :.: :*:*.* * : : . : . *: ** :*:* ****:*:: *:*..::*:*** ::*. . : : *. * : :.*. :: .: ****::*::*: *:*:*: *:*: . .:: : * * *: : . * *.. :: ***:**:*::. .* *:*: .*:::::* .* .::..:* : *: *.*:: . . :.: : *: :* :.. . . . :: ", "identical_positions": 138, "similar_positions": 306, "identity": "14.11%" }, { "cls_id": "homologset.agr.HGNC:32790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6VBQ8-1", "uniprot_id": "PNO1_RAT", "id": "Q6VBQ8-1", "name": "RNA-binding protein PNO1", "aln": "----METQNTGTEDGFTPVTHRGG-----------RRAKKRQAEQSSAAGQDGDAGRMDTEEARPAK--------------RPVFPPLSGDQLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTC-KDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPS7-1", "uniprot_id": "PNO1_MOUSE", "id": "Q9CPS7-1", "name": "RNA-binding protein PNO1", "aln": "----METQSTGTEDGFTPVTHRGG-----------RRAKKRQAEQSSAAGQDGEAGRMDTEEARPAK--------------RPVFPPLSGDQLLTGKEETRKIPVPGNRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTC-KDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVHVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRX1-1", "uniprot_id": "PNO1_HUMAN", "id": "Q9NRX1-1", "name": "RNA-binding protein PNO1", "aln": "MESEMETQSARAEEGFTQVTRKGG-----------RRAKKRQAEQLSAAGEGGDAGRMDTEEARPAK--------------RPVFPPLCGDGLLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTC-KETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6VEU3-1", "uniprot_id": "PNO1_DANRE", "id": "Q6VEU3-1", "name": "RNA-binding protein PNO1", "aln": "----MESVSDSTAEVSATMDCDGNTEA-------FEKVKSKKREKCKRAAAEMDTQTEESSSSAPVK--------------RPHFPALSGDQLGGGVDEMRKVPVPSHRYTPLKENWLKIFTPIVENLQLQVRFNLKTRQVEIKTC-KETQDIGALTRAADFVKAFVLGFQVEDALALIRLDELFLETFDVTDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTKTRIVLADTKIHILGSFQNIKMARTAICNLILGSPPSKVYGNLRAVATRSAERF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR89-1", "uniprot_id": "PNO1_DROME", "id": "Q9VR89-1", "name": "RNA-binding protein pno1", "aln": "----MEAENIR-ADAFEPAKRATK------------RGASGGGQQDVEMQVDEATGIEG--QVLGSS--------------RASAPPKAKR----ARSELRKVSVPPHRYSSLKEHWMKIFTPVVEHMKLQIRFNMKARQVELRVG-PETPDIANLQRGADFVRAFLCGFEVDDALALLRLEDLFVESFEIKDVKTLRGDHQSRAIGRLAGKGGRTKFTIENVTKTRIVLADSKIHILGSYQNIQLARRAVCNLILGSPPSKVYGNLRAVASRLSERM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99216-1", "uniprot_id": "PNO1_YEAST", "id": "Q99216-1", "name": "Pre-rRNA-processing protein PNO1", "aln": "----MVAPTALKKATVTPVSGQDGGSSRIIGINNTESIDEDDDDDVLLDDSDNNTAKEEVEGEEGSRKTHESKTVVVDDQGKPRFTSASKTQGNKIKFESRKIMVPPHRMTPLRNSWTKIYPPLVEHLKLQVRMNLKTKSVELRTNPKFTTDPGALQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVKTLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKERY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . :. : :. .. . * **: ** :* :.*:: * **:.*:**:: **:*:*:*::.**::. * * . * :.***::** **:::*::**:**::*::*:*::.***.* *** ******:***.*:***:***.*:******* ::****.: :*::** :: .****.**.*****:*:**:* :* ", "identical_positions": 93, "similar_positions": 73, "identity": "33.45%" }, { "cls_id": "homologset.agr.HGNC:328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIA7-1", "uniprot_id": "D3ZIA7_RAT", "id": "D3ZIA7-1", "name": "", "aln": "MEKFSVSAILLLVAISGTLAKDTTVKSGSKKDPKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNRPLMVIHHLDECPHSQALKKVFAENKEIQKLA-EQFVLLNLIYETTDKHLSPDGQYVPRIVFVDPSLTVRADITGRYSNRLYAYEPSDTALLHDNMKKALKLLKTEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88312-1", "uniprot_id": "AGR2_MOUSE", "id": "O88312-1", "name": "Anterior gradient protein 2 homolog", "aln": "MEKFSVSAILLLVAISGTLAKDTTVKSGAKKDPKDSRPKLPQTLSRGWGDQLIWTQTYEEALYRSKTSNRPLMVIHHLDECPHSQALKKVFAEHKEIQKLA-EQFVLLNLVYETTDKHLSPDGQYVPRIVFVDPSLTVRADITGRYSNRLYAYEPSDTALLYDNMKKALKLLKTEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95994-1", "uniprot_id": "AGR2_HUMAN", "id": "O95994-1", "name": "Anterior gradient protein 2 homolog", "aln": "MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLA-EQFVLLNLVYETTDKHLSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RZ65-1", "uniprot_id": "AGR2_DANRE", "id": "Q5RZ65-1", "name": "Anterior gradient protein 2 homolog", "aln": "MLKGLLSVLLVMVALSSALGKPE--KTTPKKE-KEKR--VPQTLSRGWGDQLIWAQTYEEALFWSRSKNKPLMVIFHLEDCPHSQALKKAFAEDKEIQKLADEDFVILNLVYETTDKHLSPDGQYVPRIIFVDPSMTVRADITGRYSNRMYAYEPADMKLLLSNMQRALKFLKTEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :*.:*::**:* :*.: *. .**: *:.* :**************:*******: *::.*:***:*.**::*********.***.******* *:**:***:******************:*****:*************:*****:* ** .**::***:*****", "identical_positions": 121, "similar_positions": 38, "identity": "68.75%" }, { "cls_id": "homologset.agr.HGNC:3280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G061-1", "uniprot_id": "EIF3B_RAT", "id": "Q4G061-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAAPEAAEERAEPARQQPVSESPPTD---EAAGSGGSEVGRTEDAEEDA---EARPEPEVRAKPAAQSEEETAASPAASPTPQSAQ-----EPSAPGKAEAGGEQAR-HPSAR-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYP--EEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKSNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZQ9-1", "uniprot_id": "EIF3B_MOUSE", "id": "Q8JZQ9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPARQQPASESPPTD---EAAGSGGSEVGQTEDAEEDA---EAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSPSQEPSAPGKAEAVGEQARGHPSAG-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYP--EEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKSNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55884-1", "uniprot_id": "EIF3B_HUMAN", "id": "P55884-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYP--EEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKNNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WET9-1", "uniprot_id": "X1WET9_DANRE", "id": "X1WET9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MRDTENMEA------------------------------------------------------------------------------------------------------------------------------------EMEYDDEEEPSFSDPEDFDDDISDQELLGDVLRDKPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNEFYP--DADGKTKGYIFLEYSAPSHAHEAVKNADGYKLDKQHTFRVNLFTDFDKYMS--ICDEWEAPEKQPFKDFGNLRHWMEDPDCRDQYSVIYDSGE---RTGIFANDVKEPIEVEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYVVTFS------------PLMDTKDDPQAIIIWDVLTGQKKRGFHCESS--AHWPIFKWSPDGKFFARMTQDMLSIYETPS-MGLLEKKSLKINGIKDFSWSPG-------------DNIIAFWVPEDKDIPARVTLMQFPSRNEMRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKDSIIAFAWEPNGSKFAVLHG--------ESPRINSSFYHVKSNGK------IDLIKMFDKQQANSIFWSPQGQFLVLAGLRSM---NGALAFVDTS---------------DCTMMNIAEHYMASDVEWDPTGRFVVTSVSWWSHKVDNAFWLWTFQGRLLQKNNKERFCQLLWRPRPPSLLTQEQIKLIKKDLKKYSKIFEQKDRLSQSKASKELVDKRRTMMEEYRKHRKRAMDMYQEQRPLRLELRGGVDTDELDSNVDDWEEETIEFFINEEIIPIGDL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E940-1", "uniprot_id": "EIF3B_DROME", "id": "Q0E940-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MAKKKSEEHSG--------------------------------------------------------------------------------------------------------------------------------TDANDSDYQEEPNFDDPPGFVDNISDEDLLGDMLAQRPSEADGVESVVVVDNIPKVEPVRLEKLKLVINKLFSNYGEIVNVVYPV-DEEGKTKGYAFMEYKQARQAEEAVKKLNNHRLDKNHTFAVNLFTDFQKYEN--IPEKWEPPTVQTFKVQSDLYNFINDPDTYDQYCVAAETAPNCVQVGFWQNVLPEPFELETRERFTDTFVKWSPLGTYVVTFHKPGVAIWGGSSFQKIQKFPHPGTQFVEFSPCENYLVTYG------------PTPTG----QKIIIWDIRTGAEKRSFVADGM--SVLSMFRWSHDDKFVARMGENSIHIYETPS-FYLLDLKSIKIPGIRGFSWSPT-------------DNVIAYWVEEQNQIPARVTLMEIPKKREIRNKNLFHVADCKLHWQKSGDYLCVKVDRYSKLKKDKKDLDVKFLGMFYNFEIFHMREKEIPVDSVEIRELILAFAWEPVGNKFSIIHG--------ETNSSNVSFYEVNKGVK------PSLVKRLEKKSCTHLFWSPRGQFIVMANLT-----MGTFEFVDSTN--------------DYIITASPDHFRASEVEWDPTGRYVVTGVSSWKVKEDTGFNMYTFQGRIIKRTILKNFVQFLWRPRPPTLLSEEKQKEIKKNLKKYYAAFEQKDRLRLTRASKELLEKRSQLRETFMEYRNKRIAEWAEQKSRRIMLRGHVDTDNLET--DEVDEEIVEFLVKEEVTLLE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06103-1", "uniprot_id": "EIF3B_YEAST", "id": "P06103-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MKNFLPRTLKNIYELYFNNISVHSIVSRN------------------------------------------------------------------------------------------------------------TQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFN---EEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGK----------TQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . .*.* :.: :: . : * ..:. :**:. * : . :: ** .: .:**: *:: * :* : *****: *:* .* . :*. .. :** :* : : :.*.::* . : :: * .* ..* :: : . **: : : .:: : :* * .:: .:*::** ***: ::*: *:: *** .*.::::* * ..: ..** *.*:**:. . : : ***: :* * .:.:** :.*: *** : : ::::.. : *: *::* **:.**::* . ::*:*. * :: .. .*: :.* . :: **.:* : .****:..::**.:*:* .* : . *::* :: *:::**: **::: :: *.*** *.:* : . ** :. * .*:* : * .. : *** *:*:*:. * . : * * . . : *::: ***:**:*.: * . * : .: ::.: *.:::. * :: *****.::*:: : * ::*:*::: **::* : * ::*: :: : : : ::*: :. :: *:.: : :: ** :* : ", "identical_positions": 149, "similar_positions": 249, "identity": "16.72%" }, { "cls_id": "homologset.agr.HGNC:3282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60843-1", "uniprot_id": "IF4A1_MOUSE", "id": "P60843-1", "name": "Eukaryotic initiation factor 4A-I", "aln": "MSASQD-----SRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60842-1", "uniprot_id": "IF4A1_HUMAN", "id": "P60842-1", "name": "Eukaryotic initiation factor 4A-I", "aln": "MSASQD-----SRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7F7A6-1", "uniprot_id": "F7F7A6_RAT", "id": "F7F7A6-1", "name": "RNA helicase", "aln": "MWAWQQRPHLGAVSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02748-1", "uniprot_id": "IF4A_DROME", "id": "Q02748-1", "name": "Eukaryotic initiation factor 4A", "aln": "MDDRNE-------IPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10081-1", "uniprot_id": "IF4A_YEAST", "id": "P10081-1", "name": "ATP-dependent RNA helicase eIF4A", "aln": "MS--------------EGITDIE-ESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQ--IVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATLLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* .:* *. *::.:.:: .****:* *.****::.****:*********:* :.* **:**********.**:*: **:*: .:: ***:******** ***:*****. :* *******.. :.. *. ::*******:* ::*: : .. **:*:********* ***:** ::* * . .**:******* *****: ***:*: *****:*******:***:**:.*::* * ***:::::**:*** ******: ** :: .*****::.*: *::*:.**::*******:**:**********************:*:*********************::*::* ::::* ** * ***:* ::* *: ", "identical_positions": 233, "similar_positions": 103, "identity": "56.55%" }, { "cls_id": "homologset.agr.HGNC:3284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14240-1", "uniprot_id": "IF4A2_HUMAN", "id": "Q14240-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "MSGGSADYN----REHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RKI1-1", "uniprot_id": "IF4A2_RAT", "id": "Q5RKI1-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "MSGGSADYN----REHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10630-1", "uniprot_id": "IF4A2_MOUSE", "id": "P10630-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "MSGGSADYN----REHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R166-1", "uniprot_id": "F1R166_DANRE", "id": "F1R166-1", "name": "RNA helicase", "aln": "MSSGSADYNSSRDRDHGGPEGMEPDGVIESNWNEITDNFDDMNLKETLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEQKETQALVLAPTRELAQQIQKVILALGDYMGASCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLSTNIQVVLLSATMPADVLEVTTKFMREPVRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02748-1", "uniprot_id": "IF4A_DROME", "id": "Q02748-1", "name": "Eukaryotic initiation factor 4A", "aln": "----MDDRN---EIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10081-1", "uniprot_id": "IF4A_YEAST", "id": "P10081-1", "name": "ATP-dependent RNA helicase eIF4A", "aln": "--------------MSEGITDIE-ESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQ--IVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATLLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:: :. *::.:.:: :****:* * ****::.****:*********:* :.* **:**********.**:*: **::: . : ***:******** ***:*::**. :* *******.. :: . *. :********:* ::*: : .. **:*:********* ***:** ::* * . **:******* *****: ***:*: *****:***********:**:.*::* * ***:::::**:*** ******: ** :: .*****::.*: *::*: **::*******:**:**********************:*:**********************:*::* ::::* ** * :**:* ::* *: ", "identical_positions": 229, "similar_positions": 101, "identity": "55.58%" }, { "cls_id": "homologset.agr.HGNC:3285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0R4IMF6-1", "uniprot_id": "A0A0R4IMF6_DANRE", "id": "A0A0R4IMF6-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAASAKKNKK-KGKTLTLTDFLAEDSGGNAPPSYAPPKPTSWADETDDLEGDVTTSWHT--------------------------------------------EDEVYRAPPIDRSILPTAPRAAREPNVDRSRLPRSPPYTAFLGNLPYDVTEDSIKNFFRG-----LSISAVRLPREPS-----NPERLKGFGYAEFDDVESLLQALSLNEENLGNRRIRVDIADQSNEKERD--DRSVSGRDRNRS------DRDMGPDKTDSDWRARPKSE--ADDGPRR-DDAFAERSKDRYDSDRHREGQRWDN-----DRYDGG--RDRY-----RERYDDRERRDYDRG--------------------------------------------------------------------------FDSRSG-GRRPFGSGFRRDYDDRRDDFRG--------SGDRYGDREER-----------FERRDERRDDRGPPQRPKLNLKPRSVPKDEEPSRGPSASS-------------GRAASIFGGAKPVDTAAKEREVEERLKKEQDRLQRQLEEDKNRG------PERKPRERHPSWRSED-QGTERSRTGSESSQTGNPPS--RGQRRRESERSVENEVFSSRDEELSSHGSQSPASKQEALPLKVVPAPPPKENAWAKRSAMSAGSTESDSKP-AVSPSSAAPPRSLP----------GSGDVPQRNKDENKADGVRRD--------RGPSRGRGGASGSGAGRGRG-DAASRDRRKE-TDRKD----------------------------------------------------------------------------------------ARRERDLRPAPEPKKFEESPSPKFSSASKYAALLMDGEQAGEEDGGN--------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q8G3-1", "uniprot_id": "F1Q8G3_DANRE", "id": "F1Q8G3-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAASAKKNKK-KGKTLTLNDFLADETGGNAPPSFPTTKATSWADETDDLEGDVSTSWHT--------------------------------------------VEDTYRAPPIDRSILPTAPRAAREPNVDRSRLPRSPPYTAFLGNLPYDVSEESIRDFFRG-----LAISAVRLPREPN-----NPERLKGFGYAEFDDIESLLRALSLNEENLGNRRIRVDIADQSNDKERD--SGMMSGRDRDRDRG---RGMDSGPDKTDSDWRARPSSD--QDDGPRK-DDGYGDKSRDRYESDRFRDGPRRDDRFSGRDRYDDRDRKDRYDDRDRRDRFDDRGSRDYDRGG-------------------------------------------------------------------------FDSRGG-GRRGFSSGFRRDYEDRRD-------------GDRFGDRED--------------RRDEGREERGPPQRPKLNLKPRSIPKEEEQSGSVSPQSNPTNT--------SRASSIFGAAKPVDTAAKEREVEERLKKEQERLQRQLEEDKNRP------SERRPRDRDPSWRSEE-PPKERQHTGSESSHP-------KGSRCRDDEHS-ENEVFSGQESEPISPTSPSPTSNQGSLPLKVMPAPPPKENAWAKR-SLGGGANEKEAPPSANAPINKSAPRPN-----------RSADERESGKDENRVDGVRKDKVLPAGRGGGGGVGRGGGSVEGVGKGRGVDCPNKEKRREPSDRKE----------------------------------------------------------------------------------------VKRDKDPRIASEPKKYEESAPPKFSSASKYAALLMDGDQGEEGDGEE--------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BGD9-1", "uniprot_id": "IF4B_MOUSE", "id": "Q8BGD9-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAASAKKKNK-KGKTISLTDFLAED-GGTGGGSTYVPKPVSWADETDDLEGDVSTTWHSN-------------------------------------------DDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEDSIKDFFRG-----LNISAVRLPREPS-----NPDRLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD--DRSF-GRDRNRD-----------SDKTDTDWRARPTTDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDG-YRDG-----YRDGPRRDMDRYGG---RDRYDDRGSRDYDRG--------------------------------------------------------------------------YDSRIGSGRRAFGSGYRRDDDYRGG-------------GDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPRLNLKPRSAPKEDDASASTSQSS--------------RAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPK---------LDRRPRERHPSWRSEETQERERSRTGSESSQTGASATSGRNTRRRESEKSLENETLN-KEEDCHSPTSKPPKPDQ---PLKVMPAPPPKENAWVKR-SSNPPARSQSSDTEQPSPTSGGGKVAAV----------QPPEEGPSRKDGNKVDVVGAT------------QGQAGSCSRGPG-----DGGSRDHWKD-LDRKD----------------------------------------------------------------------------------------GKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDEDEGDDCTE-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23588-1", "uniprot_id": "IF4B_HUMAN", "id": "P23588-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAASAKKKNK-KGKTISLTDFLAED-GGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSN-------------------------------------------DDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRG-----LNISAVRLPREPS-----NPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD--DRSF-GRDRNRD-----------SDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDG-YRDG-----YRDGPRRDMDRYGG---RDRYDDRGSRDYDRG--------------------------------------------------------------------------YDSRIGSGRRAFGSGYRRDDDYRGG-------------GDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQST--------------RAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPK---------LERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLN-KEEDCHSPTSKPPKPDQ---PLKVMPAPPPKENAWVKR-SSNPPARSQSSDTEQQSPTSGGGKVAPA----------QPSEEGPGRKDENKVDGMNAP------------KGQTGNSSRGPG-----DGGNRDHWKE-SDRKD----------------------------------------------------------------------------------------GKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGEDYAE-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7PLL3-1", "uniprot_id": "Q7PLL3_DROME", "id": "Q7PLL3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASAGKKGKKNKGTVISLQSFLCNSDAPVGTTQVSKKIRNLDGDDSDDGSGTLPLVYQL-----------------------------------------------------------PTAPRANR--IFDDNSIPHKAPFIAYINNLPFDANEDDLYEFFEG-----INLISLRLPREDG-----ENGRSRGFGYVELENREDLIHVLSLPDPSIKGRRIRIELSNENDQQSRQKSNRRFDGFGNNGD------------NRDSGNWRRDSQNNGSNFGYSSNFERSFNRERKSLPDRDDVNTPGSWRTS--------------------ARPQSIDTSPTRREVEQ-------------------------------------------------------------------------VSEKYREGRVKIADRYSREETSKVE-------------------------------------EERPKLNLKPRTLPLPDVKTIEFEKCDVDEFNLDKQGG------------TSSLNVFGSAKPVDTAARELEIEQRLALARKQDKGRR--------------EQGLNEKLAELQVDKNDNESLSATVS----------------WRTNQDYKESDKIN------------------------------------------------------------------------------KCPGEKQRDEEIHRLNHARGQ-------------------------------FNRPELLREKPNAN----------------------------------------------------------------------------------------GESKRDCRNDRSVSKKTSQNDLVLQSSNKYSGLDNEGSE----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34167-1", "uniprot_id": "IF4B_YEAST", "id": "P34167-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPPKKTVKKMDLTSFLNDDTFGSSWAEEDVDLNKITIPIETANANTIPLSELAHAKNNSNN----------------------------------------TRSGGFGGSFGGRSRLDPALGGGSSDRREEYPVPDAPPYRAVINNIPWDITPEGVQAWVEDGLVKPEAVEEVVLPKNLR-----DPTRLKGNAFVTLKERADLVAVLKFNGTKLNERTVYVSVAAPRRGGGADVDWSSARGSNFQGD---------GREDAPDLDWGAARGSN-------------FRGPRREREEVDIDWTAARGSN------------------------FQGSSRPPRREREE-------------------------------------------------------------------------VDIDWSAARGSNFQGSSR-----------------------------------------------------PPRR-----------EREEPDIDWSAAR---------------GSNFQSSSRPPRREREEPDIDWSAARGSNFQSSSRPPRR----------EREKEEPALDWGAARGAQFGKP---------------------QQTKNTYKDRSLTN-----------------------------------------------------------------------------KKTTDEQPKIQKSVYDVLRTE---------------------------------DDDEDEEAEKQN----------------------------------------------------------------------------------------GDAKENKVDAAVEKLQDKTAQLTVEDGDNWEVVGKK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I6AQ81-1", "uniprot_id": "A0A8I6AQ81_RAT", "id": "A0A8I6AQ81-1", "name": "", "aln": "MLALSSARRSASEVGATPYPILLLLVPRAQCSSSQESPTLSRSTSKNPVHPSVMGMRSQAVEEGVPPSVPRWTSFCIVKPRKAEPHSFREKVFRKKAPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVHDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKAAMELQPSQHRYVGYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYHITGPGPRQICISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGPRLNFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTPRNDPSVSVDYNMTEPAVRWDSYENFNQHHEDSVDGSLAHTRGPLDGSPYAQVQRVPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPPPTAAERQELDRLLGGCGVASAGRGAGRETAILDDEEQPSVGGGLHLGMYPGHRPGLSRRCSCRQGLREPCGVPNGGYYRPEGTLERRRPPYGGYEGHPQGYTEASVEKRRLCRSLSEGPYPYAPELGKPANGDFGYRPAGYREVVILEDPGVPALCSCPACEEKMALPTAALYGLRLEREAGEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPVPDYGCLKSPKVGEEGHEGCSYAVCPEGRYGHPGYPALVTYGYGGAVPSYCPAYGRAPHSCGSPSEGRGYPSPGAHSPQAGSVSPGSPPYLQSRKLGYEAPAEDGRDKYSLPGPLASAGPLASTESPEPSWRDGSSGHSTLPRSPRDAQCSASSELSGPSTPLHTSSPVQGKESTRRQDTTRSPSLAPTQRLSPGEALPSVVQGVTEKTPELLASSRPEPLDPSPFSQTSTPSSPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQGPQGPSDSPDGSPLTPVPTQMPWLVGSPEPPQSSPTPAFPLATSYETNGPTQPPLPEKRHLPGSGQQSSPPARGTNQHVTFASPLPDVTQPPEHPLQENQSSVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETSEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKVFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : . . . . .: . : . .* : .: . . * : . * * . :.: . : : :. : * . : .: . : . : * : . * . : . . . .. . : * : : : . . : : : . . .. : ", "identical_positions": 9, "similar_positions": 62, "identity": "0.62%" }, { "cls_id": "homologset.agr.HGNC:3287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63073-1", "uniprot_id": "IF4E_MOUSE", "id": "P63073-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "------------------MATVEPETTPTTNPP-----------PAEEEKTESNQEVANPEHYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHPLQNRWALWFFK--NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63074-1", "uniprot_id": "IF4E_RAT", "id": "P63074-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "------------------MATVEPETTPTTNPP-----------PAEEEKTESNQEVANPEHYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHPLQNRWALWFFK--NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06730-1", "uniprot_id": "IF4E_HUMAN", "id": "P06730-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "------------------MATVEPETTPTPNPP-----------TTEEEKTESNQEVANPEHYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHPLQNRWALWFFK--NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DFS6-1", "uniprot_id": "IF4EA_DANRE", "id": "Q9DFS6-1", "name": "Eukaryotic translation initiation factor 4E-1A", "aln": "------------------MATAEPETS--TNPS-----------NSEEKNEENEQQIVSLEDYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHPLQNRWALWFFK--NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRADLDRFWLETLLCLVGEAFDDHSDDVCGAVVNIRTKGDKIAIWTTDYENKDAIVHIGRVYKERLGVPPKVIIGYQSHADTATKSGSTTKNKFVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48598-1", "uniprot_id": "IF4E_DROME", "id": "P48598-1", "name": "Eukaryotic translation initiation factor 4E1", "aln": "-MQSDFHRMKNFANPKSMFKTSAPSTEQGRPEP---------PTSAAAPAEAKDVKPKEDPQETGEPAGNTATT----------------------------------------------------------------------------------------------------------------------------------------------------------------TAPAGDDAVRTEHLYKHPLMNVWTLWYLE--NDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSK-TDLDNLWLDVLLCLIGEAFD-HSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRY0-1", "uniprot_id": "Q9VRY0_DROME", "id": "Q9VRY0-1", "name": "eIF-4F 25 kDa subunit", "aln": "----------MLTTQQTEFKMMDNGTETLADSP---------SSSSEDLKTLSDMDIRKPVTEIVDLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKHPLENTWTLWYLE--NDRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGSK-AELDKLWLDVLLILIGEAFE-NTEEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLLVLPP-HQLQYQLHKDTMCKQGSVIKAVYCV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5B3-1", "uniprot_id": "Q9W5B3_DROME", "id": "Q9W5B3-1", "name": "eIF-4F 25 kDa subunit", "aln": "MLPNSFYRMRDFANPRTMFKSCANNNEYPTQGPQKVESPTDVTQPAAAPQSTEDTQPEKTQEPMNDPNKTSPSEPQKRGKGNRKGKKNQKNAPRTPSQTSKSSRSNNPGKDGKSTGNDDNEKGKGQGKQMVQQKENSPEQEQSTSAQYRKNVLDKDLQDKKLIEKNMQGKIITQENLLGQKVLMRLSEQKLLSLRLEPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLE--NDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLTKSAK-MALDSFWMDAMLCLIGEACK-HSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSB6-1", "uniprot_id": "Q9VSB6_DROME", "id": "Q9VSB6-1", "name": "eIF-4F 25 kDa subunit", "aln": "-MASAQVQSFDIMKQQDQQHQLNSIHKHHHH------------HEGVPLESNSPEPIDEEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQVEYKHPLEHVWTLWYLE--NDRTKHWKDMLNEITEIDSVETFWSLYHTIKTPAELKIGCDYSVFKKGIKPMWEDEANIKGGRWLVTVSKSAK-AELDQIWLDILLLMVGQNFE-YSDEICGAVINIRNKSNKISVWTANGSNEMAILEIGQKLKILLHLQS-HSLQYQLHSDAMSKFNSGVKSVYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSG1-1", "uniprot_id": "Q9VSG1_DROME", "id": "Q9VSG1-1", "name": "eIF-4F 25 kDa subunit", "aln": "-MVYTGYVSNGLQNAEETAWVPYGDPNDWSHGL--------AVYDGLELMSGNEEELQPSLNRVMKNID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDLAMKHPLEHTWTLWHLE--NDRTKRWAEMLVDVTSFNTVEDFFSVYYFVKPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLDKASR-TYIDKMWHDLLLCMIGECFQ-HSDEICGVVINVRNKANKLSLWTKDSRNVEAILSIGRQIKELLHLGI-MEIQYQVHKDAMVNHGPNVNAIYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAR1-1", "uniprot_id": "Q9VAR1_DROME", "id": "Q9VAR1-1", "name": "eIF-4F 25 kDa subunit", "aln": "---------------MENLRQTKESSEFKMGTS---------------LDNNKLASLGATN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHRLQNTWTLWGVK--YDPEISWEDMLKEIDSFNTVEDFWNLYFRIDTPSKLNRGCDYMLFKKGIRPMWEDPPNKGGGRWTYKVDKRST-AELDKTWLDVLLCMIGEACD-HCDQICGAFVRIRKNINKISVWTKADAGDECNEQC--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07260-1", "uniprot_id": "IF4E_YEAST", "id": "P07260-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "------------------MSVEEVSKKFEENVS------------VDDTTATPKTVLSDSAHFD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLR--GKGADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTK-SEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHSSANGRHPQPSITL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * *:** : * * : .:: ** *: : : . .: ** :*:..:.* *** * **:* : :* * :* ::*: . .:: *..: :* :*:::*. . ", "identical_positions": 29, "similar_positions": 40, "identity": "6.7%" }, { "cls_id": "homologset.agr.HGNC:3288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62622-1", "uniprot_id": "4EBP1_RAT", "id": "Q62622-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 1", "aln": "MSAGSSCSQTPSRAIP--TRRVALGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVAKTPPKDLPTIPGVTSPTSDEPPMQASQSHLHSSPEDKRAGGEESQFEMDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60876-1", "uniprot_id": "4EBP1_MOUSE", "id": "Q60876-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 1", "aln": "MSAGSSCSQTPSRAIP--TRRVALGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVAKTPPKDLPAIPGVTSPTSDEPPMQASQSQLPSSPEDKRAGGEESQFEMDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13541-1", "uniprot_id": "4EBP1_HUMAN", "id": "Q13541-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 1", "aln": "MSGGSSCSQTPSRAIPA-TRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVTKTPPRDLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ56-1", "uniprot_id": "4EBP_DROME", "id": "Q9XZ56-1", "name": "Eukaryotic translation initiation factor 4E-binding protein", "aln": "MSASPTARQAITQALPMITRKVVISDPIQMP-EVYSSTPGGTLYSTTPGGTKLIYERAFMKNLRGSPLSQTPPSNVPSCLLRGTPRTPFRKCVPVPTELIKQTKSLKIEDQE-QFQLDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**...:. *: ::*:* **:*.:.* :*:* **:******:*******::**:* *: : *.**:::*** ::*: :* : . :.* ...:. : .:* **::*:", "identical_positions": 43, "similar_positions": 45, "identity": "36.13%" }, { "cls_id": "homologset.agr.HGNC:3289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0I3-1", "uniprot_id": "A0A8I6A0I3_RAT", "id": "A0A8I6A0I3-1", "name": "", "aln": "MSASAGGGHQPSQSRAIPTRTVAISDAAQLPQDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPMAQTPPCHLPNIPGVTSPGALMEDSKVEVNNLNNLNNHDRKHAVGLCEAARAPDVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70445-1", "uniprot_id": "4EBP2_MOUSE", "id": "P70445-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 2", "aln": "MSASAGGSHQPSQSRAIPTRTVAISDAAQLPQDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPMAQTPPCHLPNIPGVTSPGALIEDSKVEVNNLNNLNNHDRKHAVG-DEAQFEMDI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13542-1", "uniprot_id": "4EBP2_HUMAN", "id": "Q13542-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 2", "aln": "MSSSAGSGHQPSQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVG-DDAQFEMDI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ56-1", "uniprot_id": "4EBP_DROME", "id": "Q9XZ56-1", "name": "Eukaryotic translation initiation factor 4E-binding protein", "aln": "MSASPTARQAITQALPMITRKVVISDPIQMPEVYSSTPGGTLYSTTPGGTKLIYERAFMKNLRGSPLSQTPPSNVPSCLLRGTPRTPFRKC-VPVP--TELIKQTKSLKIE-DQEQFQLDL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*. . : :*: .: **.*.***. *:*. *.:******:*******::**:* *: : *.**::****.::*. :* : :... * * .:* :: :. : : *: ", "identical_positions": 43, "similar_positions": 43, "identity": "35.25%" }, { "cls_id": "homologset.agr.HGNC:329", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25304-1", "uniprot_id": "AGRIN_RAT", "id": "P25304-1", "name": "Agrin", "aln": "------------------------------MPPLPLEHRPRQE--------------------------------------------PGASMLVR-------------------YFMIPCN------------ICLILLATSTLGFAVLLFLSNYK------PGIHFTPAPPTPPDVCRGMLCGFGAVCEPSVEDPGRASCVCKKNACPATVAPVCGSDASTYSNECELQRAQCNQQRRIRLLRQGPCGSRDPCANVTCSFGSTCVPSADGQTASCLCPTTCFGAPDGTVCGSDGVDYPSECQLLSHACASQEHIFKKFNGPCDPCQGSMSDLNHICRVNPRTRHPEMLLRPENCPAQHTPICGDDGVTYENDCVMSRIGATRGLLLQKVRSGQCQTRDQCPETCQFNSVCLSRRGRPHCSCDRVTCDGSYRPVCAQDGHTYNNDCWRQQAECRQQRAIPPKHQGPCDQ-TPSPCHGVQCAFGAVCTVKNGKAECECQRVCSGIYDPVCGSDGVTYGSVCELESMACTLGREIQVARRGPCD--PCGQCRFGSLCEVETGRCVCPSECVESAQPVCGSDGHTYASECELHVHACTHQISLYVASAGHCQTCGEKVCTFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYLSACELREAACQQQVQIEEAHAGPCEPAECGSGGSGSGEDDECEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPRSPVCGSDGVTYGTECDLKKARCESQQELYVAAQGACRGPTLAPLLPVAFPHCAQTPYGCCQDNFTAAQGVGLAGCPSTCHCNPHGSYSGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGHSGCTPCSCDPRGAVRDDCEQMTGLCSCRPGVAGPKCGQCPDGQVLGHLGCEADPMTPVTCVEIHCEFGASCVEKAGFAQCICPTLTCPEANSTKVCGSDGVTYGNECQLKAIACRQRLDISTQSLGPCQESVTPGASPTSAS---MTTPRHILSKTLPFPHNSLPLSPGSTTHDWPTPLPIS-PHTTVSIPRSTAWPVLTVPPTAAASDVTSLATSIFSESGSANGSGDEELSGDEEASGGGSGGLEPPVGSIVVTHGPP--IERASCYNSPLGCCSDGKTPSLDSEGSNCPATKAFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFWSVRLRELGPGKLVRAIVDVHFDPTTAFQASDVGQALLRQIQVSRPWALAVRRPLQEHVRFLDFDWFPTFFTGAATGTTAAMATARATTVSRLPASSVTPRV-YPSHTSRPVGRTTAPPTTRRPPTTATN-MDRPRTPGHQQPSKSCDSQPCLHGGTCQDQDSGKGFTCSCTAGRGGSVCEKVQPPSMPAFKGHSFLAFPTLRAYHTLRLALEFRALETEGLLLYNGNARGKDFLALALLDGRVQFRFDTGSGPAVLTSLVPVEPGRWHRLELSRHWRQGTLSVDGETPVVGESPSGTDGLNLDTNLYVGGIPEEQVAMVLDRTSVGVGLKGCIRMLDINNQQLELSDWQRAAVQSSGVGECGDHPCLPNPCHGGALCQALEAGMFLCQCPPGRFGPTCADEKSPCQPNPCHGAAPCRVLSSGGAKCECPLGRSGTFCQTVLETAGSRPFLADFNGFSYLELKGLHTFERDLGEKMALEMVFLARGPSGLLLYNGQKTDGKGDFVSLALHNRHLEFCYDLGKGAAVIRSKEPIALGTWVRVFLERNGRKGALQVGDGPRVLGESPKSRKVPHTMLNLKEPLYIGGAPDFSKLARGAAVSSGFSGVIQLVSLRGHQLLTQEHVLRAVDVSPFADHPCTQALGNPCLNGGSCVPREATYECLCPGGFSGLHCEKGLVEKSVGDLETLAFDGRTYIEYLNAVIESELTNEIPAPETLDSRALFSEKALQSNHFELSLRTEATQGLVLWIGKAAERADYMALAIVDGHLQLSYDLGSQPVVLRSTVKVNTNRWLRIRAHREHREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLQKLPVGQALPKAYGTGFVGCLRDVVVGHRQLHLLEDAVTKPELRPCPTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ASQ1-1", "uniprot_id": "AGRIN_MOUSE", "id": "A2ASQ1-1", "name": "Agrin", "aln": "------------------------------MPPLPLEHRPRQQ--------------------------------------------PGASVLVR-------------------YFMIPCN------------ICLILLATSTLGFAVLLFLSNYK------PGIHFTAAPSMPPDVCRGMLCGFGAVCEPSVEDPGRASCVCKKNVCPAMVAPVCGSDASTYSNECELQRAQCNQQRRIRLLRQGPCGSRDPCANVTCSFGSTCVPSADGQTASCLCPTTCFGAPDGTVCGSDGVDYPSECQLLRHACANQEHIFKKFDGPCDPCQGSMSDLNHICRVNPRTRHPEMLLRPENCPAQHTPICGDDGVTYENDCVMSRIGAARGLLLQKVRSGQCQTRDQCPETCQFNSVCLSRRGRPHCSCDRVTCDGAYRPVCAQDGHTYDNDCWRQQAECRQQQTIPPKHQGPCDQ-TPSPCRGAQCAFGATCTVKNGKAVCECQRVCSGGYDPVCGSDGVTYGSVCELESMACTLGREIRVARRGPCD--RCGQCRFGSLCEVETGRCVCPSECVESAQPVCGSDGHTYASECELHVHACTHQISLYVASAGHCQTCGETVCTFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYLSACELREAACQQQVQIEEARAGPCEPAECGSGGSGSGEDNACEQELCRQHGGVWDEDSEDGPCVCDFSCQSVLKSPVCGSDGVTYSTECHLKKARCEARQELYVAAQGACRGPTLAPLLPMASPHCAQTPYGCCQDNVTAAQGVGLAGCPSTCHCNPHGSYSGTCDPVTGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGHSGCTPCSCDPRGAVRDDCEQMTGLCSCRPGVAGPKCGQCPDGQALGHLGCEADPTTPVTCVEMHCEFGASCVEEAGFAQCVCPTLTCPEANSTKVCGSDGVTYGNECQLKTIACRQRLDISIQSLGPCRESVAPGVSPTSAS---MTTPRHILSRTLASPHSSLPLSPSTTAHDWPTPLPTS-PQTVVGTPRSTA---------ATPSDVASLATAIFRESGSTNGSGDEELSGDEEASGGGSGGLEPPVGSVVVTHGPP--IERASCYNSPLGCCSDGKTPSLDSEGSNCPATKAFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFWSIRLRELGPGKLVRAIVDVHFDPTTAFQAPDVGQALLQQIQVSRPWALAVRRPLREHVRFLDFDWFPTFFTGAATGTTAAVATARATTVSRLSASSVTPRV-YPSYTSRPVGRTTAPLTTRRPPTTTAS-IDRPRTPGPQRPPKSCDSQPCLHGGTCQDLDSGKGFSCSCTAGRAGTVCEKVQLPSVPAFKGHSFLAFPTLRAYHTLRLALEFRALETEGLLLYNGNARGKDFLALALLDGHVQFRFDTGSGPAVLTSLVPVEPGRWHRLELSRHWRQGTLSVDGEAPVVGESPSGTDGLNLDTKLYVGGLPEEQVATVLDRTSVGIGLKGCIRMLDINNQQLELSDWQRAVVQSSGVGECGDHPCSPNPCHGGALCQALEAGVFLCQCPPGRFGPTCADEKNPCQPNPCHGSAPCHVLSRGGAKCACPLGRSGSFCETVLENAGSRPFLADFNGFSYLELKGLHTFERDLGEKMALEMVFLARGPSGLLLYNGQKTDGKGDFVSLALHNRHLEFRYDLGKGAAIIRSKEPIALGTWVRVFLERNGRKGALQVGDGPRVLGESPKSRKVPHTMLNLKEPLYVGGAPDFSKLARGAAVASGFDGAIQLVSLRGHQLLTQEHVLRAVDVAPFAGHPCTQAVDNPCLNGGSCIPREATYECLCPGGFSGLHCEKGIVEKSVGDLETLAFDGRTYIEYLNAVTESELTNEIPAPETLDSRALFSEKALQSNHFELSLRTEATQGLVLWIGKVGERADYMALAIVDGHLQLSYDLGSQPVVLRSTVKVNTNRWLRVRAHREHREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLQKLPVGQALPKAYGTGFVGCLRDVVVGHRQLHLLEDAVTKPELRPCPTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00468-1", "uniprot_id": "AGRIN_HUMAN", "id": "O00468-1", "name": "Agrin", "aln": "MAGRSHPGPLRPLLPLLVVAACVLPGAGGTCPERALERREEEANVVLTGTVEEILNVDPVQHTYSCKVRVWRYLKGKDLVARESLLDGGNKVVISGFGDPLICDNQVSTGDTRIFFVNPAPPYLWPAHKNELMLNSSLMRITLRNLEEVEFCVEDK------PGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQ-APSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCD--RCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSASV-TVTTPGLLLSQALPAPPGALPLAPSSTAHSQTTPPPSSRPRTTASVPRTTVWPVLTVPP-TAPSPAPSLVASAFGESGSTDGSSDEELSGDQEASGGGSGGLEPLEGSSVATPGPP--VERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSVRAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDFDWFPAFITGATSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPKSRKVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESELANEIPVPETLDSGALHSEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRPCPTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKT2-1", "uniprot_id": "A0A8M9PKT2_DANRE", "id": "A0A8M9PKT2-1", "name": "Agrin", "aln": "MGSADRKAVYWPVWSFALVFVLLIQRCHGGCSEKELEKREEEANVVLTGTVEEILNMDPVHNTYSCKVRVWRYLKGKTMVNGEVLLDGGNKVMIGGFGDPHICDNQVATGDTRIFFVNLAPEYMWPNHKNELMLNSSLMRITLRNLEEVEHCVEDHKMIIADKPVHFTPAP--PPDGCRGKLCGFGAVCERDQADPSKGECVCKKIVCTSVVAPVCGSDSSTYSNECELEKAQCNTQRRIKVMRKGPCALKDPCSEVTCSFGSTCIQSSDGLSAKCMCPLSCENVPKHVVCGSDGLDYQSECELNMKACATQKNIRVHHQGRCDPCSDTLNSLSTACRVNPKTYQQITFAPAESCPPDEMPICASDGHTYESMCQMERTALKNNLELKKVSLGSCKEKGGCPNGCKFNAICLLDNGEFRCSCDPIQCDGTYKPLCGKDGKTYPNDCERKLQECRTQKDIPVKQQGPCDLNLESPCLKKTCEFGAVCVVKNSEAVCECSDACPQDQDPVCGSDGHTYSSSCQMKAMGCALQKQIQMQHKGPCADESCTNCSFGAICDAQTGRCVCPKGCLETRQPVCGSDGTTYDNECKLNVQACTKQLDLKVVAHGECKTCGSTVCSWGSQCVNNKCECQQCTGQPVKPVCGSDGNTYNNDCELRLASCQKQRKIEVAKPGVCD-EDCGSGGSGSGSE-TCEQDRCRRYGGTWDDDMEDERCVCELNCQIVLHSPVCGSDGNTYSSDCELKKTRCEKQIDLSVQSQGPCPTIVSPPPELVASQHCSQTVYGCCEDNKTAALGVGLAGCPSMCQCNHYGSYGGTCDPSTGQCSCKPGVGGLKCDRCEPGFWNFRGIVTENMSGCTPCNCDGVGSVRDDCEQMSGLCSCKPGVKGMKCNVCPDGSKMGVNGCDKGPKAPKSCAELVCHFGSSCVEVNGQAHCECPSPDCDEKNKTKVCGSDGVTYADRCQLKTIACRQDKEIKVEHLGQCKESIELTAKPTPFPTTHRTTPPTAHVKVTKQRHGHRTTTPDSYVVEAMPPPRLDGARKFSSPFTTHR------PTTPYKPLRTSSPPLDFDESGSGEPSGDDEMVSGMEESG------EEPLGTTVATTTLPTAEERSSCDNTAFGCCPDGKTAAVNSEGTNCPSTMRFSGFLHLDKVEGQEVFYTPEMEDPKSELFGETARSIESAMNELFRKSDVQKDFQSVRVRNLSPSNSIIAHFEAHFDPDTRFNVGDIEGALLKQLKASKDTGIVVKKPEEENIRINNYGLSTVPFFTTTTTTVASVTTPTTTTTTMSPSSAYTTLR--PITTRRPFTRTTTPAPATTTAPHVPKTTVSLMNRLGPHAHSPCDSQPCRHGGTCEEDD--NDFTCICPAGRGGAVCEKVIKYFIPSFGGKSYMAFQTMKAYHTVRIAMEFRASEMTGILLYNGQKSKKDFLSLTLVEGYVELRFNTGSGTASVISKVLVKPGRWHQLVVVRNRRNAMLSVDNEPSVEGQSPPGTDGLNLDTDLFIGGVLDDMSADVKERTSVSAGLVGCIRMLDVNNLVYNLQENGGSVLYGSAIGECGNNPCLPNPCKNGASCQVKEAEIFHCKCVNGFSGPTCADAHNPCDPNKCHPPSRCQVLPEGGYKCECPMGREGRHCEKVSDKGG--AFIPYFTGDSFLELKGLHTYNQDLRQKFSMTIVLLANDSKGMIFYNGQKTDGKGDFISLSLNDGILEFRYDLGKGPAVIRSKEKIKLNEWNTVNLERASRKGEISINGKDPVRGEAPKSRKNQHTDLNLKESLFVGGAPDFRKVARAAAIKDGFKGAIQKITLMGIPILKADNALSSTDVSMYPNHPCSKDV---CENGGRCNPQLNSYECACRHGFSGHHCQDTIFEKSAGDTEAIAFDGHTFIEYHNGVTKSQLTNEIPDPESLENPSDQSEKALLVNKFELSIRTEATHGLILWSGKGVERSDYIALAIVDGRVQMTYDLGSKPVVLRSTVRVNTNHWIRIKASRALRDGSLQVGNEAAVTGSSPLAATQLDTDGALWLGGLEELSVARRLPKAYSTGFIGCVKDVIVDGVELHLVEDALNTPKISHCSAK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:* .: * .::: :*: . : *: : .: : . : : ***..* *** *** ********* . .*.:..***** *.: ********:*********::***. ****::: :***. :***::********* *:** :*.*:** :* ..*. .****** ** .**:* :*** *::: :.:* ****..:: . . *****:* : : .*.**. . *:*..** ***. * * * . ..* *:** *.*: :. **: *:**::** .*. :**** : ***:*:*:*.:**:** .** *: *** *: ** *:***** *** * ***.*.***.:* *** .*. ******** **.* *:::: .*:* ::*:: ::*** * :* **::*:.:*******. *: ******** ** .** *:*:***:*:.* *.: * *:***. **::*: * .:* * :* * ******* ** . **** *:* :* :** *:.* *: :*********.: ***: **: ** **:* ** ***::.** * ******** **.::*.***:*** : * * :**.* . .* :* **:** ****:** *** ********* *:** :***.***** ******:******:****************:. ******.** *:********:*****:*** * **. **** :* **: .. :* :*.*: *.**: *** * *:* ** * * * ***********.:.****:***** :*. : ** *:*:: . **. . *** :. . . :*.: . . .* . .:. . : . . .* . * **** : *.*:*: .. * ** * *: *.* * **:** *:.:***.****.::::**:***:* *.*.*.*: *****:****** ****************::::***:***:*** *:*:*:*.*.: : * .:.**** * *.. *: ***:*::.*: .: *::* .*::*: ::. .. : ::: : *: :*. :**.: .:*: *. * * :*. :**:. .: ... ... :. ..****** *****:: .*:* *.***.*:***** :*:* *:*::** *::****:*:*:**** * *:*****: ****:*:*::* *::**:****.* : * * *:**:**:* : *: *.. ****.*..* *:**.*********.*::**: :: * . :** *. ** ****:**:** :* :. .*.:****::** ****:.** ** ** * *:* * ****** :.**:** ** .: *:**. ** :* **:**.* .*:.. * .*:. *.* *.***:****: :** :*::: :*:**....*:::************:**:*.: *** ******.*:***:* : *. * * *** .*** : :.. * **:***** ** *****.*::****** *:**.**: .**.*.** ::* * :*. ::.* .**: :..***:: * **. * *: :* * * **** **:. :.***.** :::****:*::** *.* :*:*:**** **:*:. : ***** *:****:*****:**:** ** **:**:*******::*::*:***:******** ****:*:*: * * *:*********.*******.*************** :*.*. *****.***:**::**:*. ***:***:..*:: *.: ", "identical_positions": 963, "similar_positions": 517, "identity": "46.28%" }, { "cls_id": "homologset.agr.HGNC:3290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEG8-1", "uniprot_id": "D4AEG8_RAT", "id": "D4AEG8-1", "name": "", "aln": "MTYPSIACCDCLHLRAVFHGFKAPAVAFLLLTMSTST--------SCPIPG------SWDQLPDGYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTIPPTVPPFKLELLKEQKQTEEEIT--DDEQFEMDM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VV3-1", "uniprot_id": "4EBP3_MOUSE", "id": "Q80VV3-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 3", "aln": "--------------------------------MSSST--------SCPIPG------CRDQLPDGYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTLPAVPPSKLELLKEQKQTEVEIT--DDEQFEMDM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60516-1", "uniprot_id": "4EBP3_HUMAN", "id": "O60516-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 3", "aln": "--------------------------------MSTST--------SCPIPG------GRDQLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTPPTAPLSKLEELKEQ-ETEEEIP--DDAQFEMDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98TT6-1", "uniprot_id": "4EB3L_DANRE", "id": "Q98TT6-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 3-like", "aln": "--------------------------------MSTNTQQ----SKSCPIPTRVLHLKDWSQLPDCYSQTPGGTLFSTTPGGTRIIYDRKFLLDCRNSPIARTPPCCLPQIPGVTIPSLHPVSKLQELKEELEEEKELAA-DDSQFEMDI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ56-1", "uniprot_id": "4EBP_DROME", "id": "Q9XZ56-1", "name": "Eukaryotic translation initiation factor 4E-binding protein", "aln": "--------------------------------MSASPTARQAITQALPMITRKVVISDPIQMPEVYSSTPGGTLYSTTPGGTKLIYERAFMKNLRGSPLSQTPPSNVPSCLLRGTPRTPFRKCVPVPTELIKQTKSLKIEDQEQFQLDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.. : *: *:*: ** ******::******::**:* *: : :.**:::***. :*. : .* : .: *: **::*:", "identical_positions": 34, "similar_positions": 31, "identity": "22.82%" }, { "cls_id": "homologset.agr.HGNC:32926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M7S7-1", "uniprot_id": "A0ABK0M7S7_RAT", "id": "A0ABK0M7S7-1", "name": "", "aln": "MRQFRSGGRLFLADFGSHDATQEKWKCLFSKGLDIADNLRVESSFLLCGSLAVEN-YELSLTESVTVQEGLCVFVPCQVKYPA----SGGSVFGYWFQDGANTNLNSPVATNDPHR-PVQQETQGRFYLVG-GIDTKNCSLDIRDARKSDTGKYFFRLDG--SVKYSFRNRMLSVHVTALTKTPNLQVTSTLVSGTSTRVICSVLWACEQGTPPIFSWMSS-----------ALTSLGRRTILSSELNLTPRPQDNGTNLICQVTFPGAGVTVERTQQLSVTYAPQKLTIRVSWGDGTET--KVLQSGASLQIQEGESLRLVCVADSNPSAMLSWKR---QTQKNFRLSKGDELQLPRVELEDQGKYICQAKNSLGTQTASVSLSIRSLLQLLAPSCSWDSEGLHCSCSSRAWPA----PSLGWRLGEGLLEGNSSNASFTVM---SSSAGPWVNSSLSLSVEFSTDHRLSCEAWNDYGVQRATIVLVPGQGVSQADKSETSGGAVQGAIWGAGLMALLAVSFCLIFFIVKFLRKKSALEVAAMEGNHLAKNLVSTINSASMISSNIPLRYPIQDHLNESESQTQ---KEEPPLATAPDIPKDEPELHYASLSFQGPRPQQPKNTETIKSVYTEIKIHKR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920G3-1", "uniprot_id": "SIGL5_MOUSE", "id": "Q920G3-1", "name": "Sialic acid-binding Ig-like lectin 5", "aln": "----------------------MRWAWLLP--------------LLWAGCLATDG-YSLSVTGSVTVQEGLCVFVACQVQYPN----SKGPVFGYWFREGANIFSGSPVATNDPQR-SVLKEAQGRFYLMG-KENSHNCSLDIRDAQKIDTGTYFFRLDG--SVKYSFQKSMLSVLVIALTEVPNIQVTSTLVSGNSTKLLCSVPWACEQGTPPIFSWMSS-----------ALTSLGHRTTLSSELNLTPRPQDNGTNLTCQVNLPGTGVTVERTQQLSVIYAPQKMTIRVSWGDDTGT--KVLQSGASLQIQEGESLSLVCMADSNPPAVLSWER---PTQKPFQLSTPAELQLPRAELEDQGKYICQAQNSQGAQTASVSLSIRSLLQLLGPSCSFEGQGLHCSCSSRAWPA----PSLRWRLGEGVLEGNSSNGSFTVK---SSSAGQWANSSLILSMEFSSNHRLSCEAWSDNRVQRATILLVSGPKVSQAGKSETSRGTVLGAIWGAGLMALLAVCLCLIFFTVKVLRKKSALKVAATKGNHLAKNPASTINSASITSSNIALGYPIQGHLNEPGSQTQ---KEQPPLATVPDTQKDEPELHYASLSFQGPMPPKPQNTEAMKSVYTEIKIHKC---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08ET2-1", "uniprot_id": "SIG14_HUMAN", "id": "Q08ET2-1", "name": "Sialic acid-binding Ig-like lectin 14", "aln": "----------------------MLPLLLLP--------------LLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDR-RVKPETQGRFRLLG-DVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGN-----------ALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFRE-GKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ----------------------------------------------RSSSSCICVT---EKQQGSWP------------------------------LVLT----------------LIRGALMGAG--FLLTYGLTWIYYTR-----------------------------------------------CGGPQQSR---AERPG--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5V7-1", "uniprot_id": "A0AB32T5V7_DANRE", "id": "A0AB32T5V7-1", "name": "", "aln": "--------------MKIISLCTIIFMLVFN---------------VLCEENADNGWNISFSPREVTAVKGLCAHISCTFTYPV----AENPIQSVIWQSCVAKDKCNLIFQNNVEKNKLKKNELGHIKMLEPDLSKNNCSIILKDIKENEK-EYTFRIKAK-------QQYTFNPTVKISIKDEPTLVVPPLSEKVEVNLTCSAPFPCPETPPVITWWIKTKEENYIKLDNNKITQVHSEHVYYSYLTLIPTSDQHDGTVGCDVRYGNKKINTNNTLEVKYVQALQIVGENT--------------------LMEGDTLNLTCTFRSHPPASNPVWRFNGNTDNLNTQTSAGTLMIANVGKEHAGIYVCEMTYMNKTLNASITINITEVN-ILGENRLKKGDTLNLTCSFKNHPQSSSNPVWSFNGDADKLKNQASAANLIIDNVTKEHAGIYACEMTYMKKTLNASITVDITGVLDFLLSIPNIFTFVAGMAFSALIFSVILCCWVCCHRGKKQKVPTANPDAEINLETVQTDVAQNGTTEQTPLHEQPDGETPKTPATPTDGAEEDEALGTEAREVDYASIDYSLLKDKPPEEAETEPTDTDYAEIKKDRTKDWKDTEDPQDGDEQVETFDQKEMGAEEELYSQVPQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . .**. :***. :.* . ** : .: ::. . : *: .: : : *:: :: ..:***: : * : :. * **:. :: :. * : . .* . ..: ** .* .* * . :: : . * *.* * .:::. .: *:* . :..:.* ::. * * : : **::* *.* *:*.* . * : : : * :.. .. * : *. : *. :.: .:* . : : .. * : :. . * : * . :.* ", "identical_positions": 51, "similar_positions": 112, "identity": "7.86%" }, { "cls_id": "homologset.agr.HGNC:32929", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6B9Z0-1", "uniprot_id": "IGFL_MOUSE", "id": "Q6B9Z0-1", "name": "Insulin growth factor-like family member", "aln": "MKIRNACAVLIEVLLFILEGVTGARKISTFSGPGSWPCN--PKCDGRTYNPSEECCVHDTILPFKRINLCGPSCTYRPCFELCCPESYSPKKKFIVKLKVHGERSHCSSSPISRNCKSNKIFHGEDIEDNQLSLRKKSGDQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWQ7-1", "uniprot_id": "IGFL2_HUMAN", "id": "Q6UWQ7-1", "name": "Insulin growth factor-like family member 2", "aln": "MVPRIFAPAYVSVCLLLLC----PREVIAPAGSEPWLCQPAPRCGDKIYNPLEQCCYNDAIVSLSETRQCGPPCTFWPCFELCCLDSFGLTNDFVVKLKVQGVNSQCHSSPISSKCESRRRFP-------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * ... :.* *::* .*:: : :*. .* *: *:*..: *** *:** :*:*:.:.. . ***.**: ******* :*:. .:.*:*****:* .*:* ***** :*:*.: * ", "identical_positions": 49, "similar_positions": 44, "identity": "34.51%" }, { "cls_id": "homologset.agr.HGNC:3293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60573-1", "uniprot_id": "IF4E2_HUMAN", "id": "O60573-1", "name": "Eukaryotic translation initiation factor 4E type 2", "aln": "---------MNNKFDALKDDDSGDHDQ---------NEENSTQKDGEKEKTERDKNQSSSKRKAVVPGP----AEHPLQYNYTFWYSRRTPGRPT--------SSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKP-----------------------------------------MWEDDANKNGGKWIIRLR--KGLAS---------RCWENLILAMLGEQFMVG-EEICGAVVSVRFQEDIISIWNKTASDQATTAR------IRDTLRRVLNLPPN--------TIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BMB3-1", "uniprot_id": "IF4E2_MOUSE", "id": "Q8BMB3-1", "name": "Eukaryotic translation initiation factor 4E type 2", "aln": "---------MNNKFDALKDDDSGDHDQ---------NEENSTQKDGEKEKTDRDKSQSSGKRKAVVPGP----AEHPLQYNYTFWYSRRTPGRPT--------SSQSYEQNIKQIGTFASVEQFWKFYSHMVRPGDLTGHSDFHLFKEGIKP-----------------------------------------MWEDDANKNGGKWIIRLR--KGLAS---------RCWENLILAMLGEQFMVG-EEICGAVVSVRFQEDIISIWNKTASDQATTAR------IRDTLRRVLNLPPN--------TIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07260-1", "uniprot_id": "IF4E_YEAST", "id": "P07260-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "--------------------------M---------SVEEVSKKFEENVSVDDTTATPKTVLSDSAHFD----VKHPLNTKWTLWYTKPAVDK-----------SESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRP-----------------------------------------EWEDEANAKGGKWSFQLRGKGADID---------ELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTKSE-DKEPLLR------IGGKFKQVLKLTDD--------GHLEFFPHSS---ANGRHPQPSITL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "E1JIV5-1", "uniprot_id": "E1JIV5_DROME", "id": "E1JIV5-1", "name": "", "aln": "-----------------MSMEKVANKQ---------YETKNWPDIVDSDDSDVDNQIDVDNLPPLEVGP----GENRLQHTYCLWFSRKETQR----------AAADYSKSLHMVGRCASVQQWWSLYSHLIRPTALKPYRELLLFKQGIIP-----------------------------------------MWEDPANSKGGQWLIRLR--KNKVD---------RAWENVCMAMLGEQFLVG-DEICGVVLQTKYPNPSIQVACSSRPIICIIYTRFVVQFGKCKIIIVTNNNKR--------NVYEFLTIIVIKIHEEMLSLLSRKCKFVNAPNELVTRIGRFLF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18916-1", "uniprot_id": "ACHG_RAT", "id": "P18916-1", "name": "Acetylcholine receptor subunit gamma", "aln": "MHGGQGPQLLLLLLATCLGAQSRNQEERLLADLMRNYDPHLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPKDYEGLWILRVPSTMVWQPDIVLGNNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLVFQSQTYSTSEINLQLSQEDGQAIEWIFIDPEAFTENGEWAIRHRPAKMLLDPVTPAEEAGHQKVVFYLLIQRKPLFYVINIIVPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLMVVTILIVVNSVVVLNVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVHPRAPAAVQDARLRLQNGSSSGWPIMTREEGDLCLPRSELLFRQRQRNGLVQAVLEKLENGPEMRQSQEFCGSLKQASPAIQACVDACNLMARARHQQSHFDSGNEEWLLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNQVPDLPFPGDPRPYLPLPD", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : :: : : : : :. : * : . : * :*:.. : * :.*:* :: * . . : : : : . * *: : .: : . : : ", "identical_positions": 9, "similar_positions": 42, "identity": "1.73%" }, { "cls_id": "homologset.agr.HGNC:32930", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6B9Z0-1", "uniprot_id": "IGFL_MOUSE", "id": "Q6B9Z0-1", "name": "Insulin growth factor-like family member", "aln": "MKIRN-ACAVLIEVLLFILEGVTGARKISTFSGPGSWPCN--PKCDGRTYNPSEECCVHDTILPFKRINLCGPSCTYRPCFELCCPESYSPKKKFIVKLKVHGERSHCSSSPISRNCKSNKIFHGEDIEDNQLSLRKKSGDQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXB1-1", "uniprot_id": "IGFL3_HUMAN", "id": "Q6UXB1-1", "name": "Insulin growth factor-like family member 3", "aln": "MRPRCCILALVCWITVFLLQCSKGTTDAP--VGSGLWLCQPTPRCGNKIYNPSEQCCYDDAILSLKETRRCGSTCTFWPCFELCCPESFGPQQKFLVKLRVLGMKSQCHLSPISRSCTRN----------------RRHVLYP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * *:: : :*:*: .*: . . *.* * *: *:*..: *****:** .*:**.:*. . **.:**: **********:.*::**:***:* * :*:* *****.*. * :: *", "identical_positions": 55, "similar_positions": 39, "identity": "38.46%" }, { "cls_id": "homologset.agr.HGNC:32931", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6B9Z0-1", "uniprot_id": "IGFL_MOUSE", "id": "Q6B9Z0-1", "name": "Insulin growth factor-like family member", "aln": "-MKIRNACAVLIEVLLFILEGVTGARKISTFSGPGSWPCN--PKCDGRTYNPSEECCVHDTILPFKRINLCGPSCTYRPCFELCCPESYSPKKKFIVKLKVHGERSHCSSSPISRNCKSNKIFHGEDIEDNQLSLRKKSGDQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6B9Z1-1", "uniprot_id": "IGFL4_HUMAN", "id": "Q6B9Z1-1", "name": "Insulin growth factor-like family member 4", "aln": "MVPRISAAIFIFELLGSNSEGVTDLR---------LWLCQPAPRCGEWTYNPLEQCCDDGVILDLNQTRLCGSSCTFWPCFQHCCLESLGSQNQTVVRFKVPGMKPDCKSSPITRICAQEYHPKSPVSRSDLI----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*. .::*:* ****. * * *: *:*. **** *:** ...** ::: .***.***: ***: ** ** ..::: :*::** * :..*.****:* * .: :. ..: : ", "identical_positions": 45, "similar_positions": 43, "identity": "31.47%" }, { "cls_id": "homologset.agr.HGNC:32933", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1W2Q6F6-1", "uniprot_id": "A0A1W2Q6F6_RAT", "id": "A0A1W2Q6F6-1", "name": "", "aln": "-MDPETRELRALEEEVAALQRECRMLQ-----NLEEKTSGAWKSFKKFSQSDSEEWESLKDLRSQLGHLKSELSFLSKLTGFNIRNYSK-MEDIGNTEQTENDTKKVLQRHRLSGNCNMVTFQLEFEVLEIETKEKKSSIITDLSIIMEPTEYSELSEFASRAEEKRDLLMFFRSLHFFVEWYEYRENTFKHFKERYPDSVYLSEGTCSHCMEIRNARLPGFELVIVWRIQIDEEGKVFPKLDLLTKVPEQALEMDKNRVIETAPLSFRSLLGVLGIEAALDSLIRLFNTDK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZ92-1", "uniprot_id": "CENPP_MOUSE", "id": "Q9CZ92-1", "name": "Centromere protein P", "aln": "-MDSETRELRALEAEVAALQRECRMLQ-----NAGEKASGAWKSFQKISQSDSEEWESLKDLRSQLEHLRSEHSFLSKLTGFNIRNYSK-MEDIVNTEETEKDTKKVLQKHRLSGNCNMVTFQLEFEVLEMETKEKKSSIITDLSIIMEPTEYSELSEFASRAEEKRDLLMFFRSLHFFVEWCEYRENTFKHFKEKYPDTVYLLEGTCSHCMEIRSTRQPGFELVIVWKIQIDEEGMVFPKLDLLTKVPERALGLDKNRVIETAPLSFRSLLGVLGIEAALDSLIRLFSGDNN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IPU0-1", "uniprot_id": "CENPP_HUMAN", "id": "Q6IPU0-1", "name": "Centromere protein P", "aln": "-MDAELAEVRALQAEIAALRRACEDPP-----APWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINIRNHSKQTEDLTSTEMTEKSIRKVLQRHRLSGNCHMVTFQLEFQILEIQNKERLSSAVTDLNIIMEPTECSELSEFVSRAEERKDLFMFFRSLHFFVEWFEYRKRTFKHLKEKYPDAVYLSEGPSSCSMGIRSASRPGFELVIVWRIQIDEDGKVFPKLDLLTKVPQRALELDKNRAIETAPLSFRTLVGLLGIEAALESLIKSLCAEENN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LV50-1", "uniprot_id": "CENPP_DANRE", "id": "Q1LV50-1", "name": "Centromere protein P", "aln": "MEQKYEEDIQKLQQEIEMLEAEQEETLRSIFVQHGDRLQQGVKSACEERGGGGAQQHAVSKLITEVRELEKDLRRQTEINGITLN--------ECFVKTLHKSERKLVQQLRLAGHCGLLLFQVEFAVTEIQEDNVLHRRVTELNIVVDGVEFKDFSAFVSRVEDTKDLLLFFRTLRTFSERCEDRRQTFQHFQEKYPDVVNLPEGCRSEIMIIRSPQLPGISMTLFWKIHVSKEGVVKPLLDLLLKMPDQALELDTKKVMEKGSDYFQSLLQLLGVEASIEGLIRAVCS----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: *: *: *. . :. . ** . .: ..* .:: .*..: : :.*:.:. .: .:. :*::*: **:*:* :: **:** : *:: .: :*:*.*::: .* .::* *.**.*: :**::***:*: * * * *..**:*::*:*** * * ** * * **.. **:.:.:.*:*::.::* * * **** *:*::** :*.::.:*... *::*: :**:**:::.**: . ", "identical_positions": 78, "similar_positions": 110, "identity": "26.53%" }, { "cls_id": "homologset.agr.HGNC:32934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZX8-2", "uniprot_id": "SO1B2_RAT", "id": "Q9QZX8-2", "name": "Solute carrier organic anion transporter family member 1B2", "aln": "---------------------------------------------MDHTQQSRKAAEAQPSRSKQTRFCDGFKLFLAALSFSYICKALGGVVMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGSILTALPHFFMGY-YKYAK-ENDIGSLGNST---LTCFINQMTSPTGPSPEIVEKG---CEKGLKSHMWIYVLMGNMLRGIGETPIVPLGISYLDDFAKEGHTSMHLGTLHTIAMIGPILGFIMSSVFAKIYVDVGYVDLNSVRITPNDARWVGAWWLSFIVNGLLCITSSIPFFFLPKIPKRSQEERKNSVS-------LHAPKTDEEKKHMTNLTKQEEQDPSN---------------MTGFLRSLRSILTNEIYVIFLILTLLQVSGFIGSFTYLFKFIEQQFGRTASQANFLLGIITIPTMATAMFLGGYIVKKFKLTSVGIAKFVFFTSSVAYAFQFLYFPLLCENKPFAGLTLTYDGMNPVDSHIDVPLSYCNSDCSCDKNQWEPICGENG-VTYISPCLAGCK--------------------------------SFRGDKKPNNTEFYDCSCISNS----GNN--------------SAHLGECPRY-KCKTNYYFYIILQVTVSFFTAMGSPSLILILMKSVQPELKSLAMGFHSLIIRALGGILAPIYYGAFIDRTCIKWSVTSCGKRGACRLYNSRLFGFSYLGLNLALKTPPLFLYVVLIYFTKRKYKRNDNKTLENGRQFTDEGNPDSVNKNGYYCVPYDEQSNETPL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJL3-1", "uniprot_id": "SO1B2_MOUSE", "id": "Q9JJL3-1", "name": "Solute carrier organic anion transporter family member 1B2", "aln": "---------------------------------------------MDQTQHPSKA--AQPLRSEKTRHCDGFRIFLAALSFSYICKALGGVIMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGTGCFIMGIGSILTALPHFFMGY-YRYAT-ENDISSLHNST---LTCLVNQTTSLTGTSPEIMEKG---CEKGSNSYTWIYVLMGNMLRGIGETPIVPLGVSYIDDFAKEGNSSMYLGTLHTIAMIGPILGFIMSSVFAKLYVDVGYVDLRSVRITPQDARWVGAWWLGFIVNGLLCIICSIPFFFLPKIPKRSQKERKNSAS-------LHVLKTDEDKNPVTNPTTQEKQAPAN---------------LTGFLWSLRSILTNEQYVIFLILTLLQISSFIGSFTYLFKFIEQQFGQTASQANFLLGVITIPTMASGMFLGGYLIKRLKLTLLGITKFVFFTTTMAYVFYLSYFLLICENKAFAGLTLTYDGMNPVDSHIDVPLSYCNSDCICDKNQWEPVCGENG-VTYISPCLAGCK--------------------------------SFRGDKKLMNIEFYDCSCVSGSGFQKGNH--------------SARLGECPRD-KCKTKYYFYITFQVIISFFTALGSTSLMLILIRSVQPELKSLGMGFHSLVVRTLGGILAPVYYGALIDRTCMKWSVTSCGARGACRLYNSRLFGMIYVGLSIALKTPILLLYVALIYVMKRKMKRNDNKILENGRKFTDEGNPEPVNNNGYSCVPSDEKNSETPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V0H7-1", "uniprot_id": "SO1B7_HUMAN", "id": "G3V0H7-1", "name": "Putative solute carrier organic anion transporter family member 1B7", "aln": "--------------------------------------------------------------------------------------------MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMALPHFFMGY-YRYSK-ETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERG---CVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQKERKVSLF-------LHVLKTNDKRNQIANLTNRRKYITKN---------------VTGFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDESQWEPVCGNNG-ITYLSPCLAGCK--------------------------------SSSGNKEP--IVFYNCSCVEVIGLQNKNY--------------SAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSAEEQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PU70-1", "uniprot_id": "A0A8M9PU70_DANRE", "id": "A0A8M9PU70-1", "name": "Solute carrier organic anion transporter family member", "aln": "----------------------------------------------------------MSTEKKKEPCCSKLKMFLAAMCFVFFAKAFQGSYMKSSVTQIERRFDVPSSLIGFIDGSFEIGNLFVIAFVSYFGAKLHRPRLIAAGCLVMSAGSFITAMPHFFQGQ-YKYESTISHFSASVNGTENVLPCLTNASLAQDSEIPTVESQA--ECEKASSSSLWLFVFLGNMLRGIGETPVMPLGLSYLDDFSREENTAFYLALIQTVGIMGPMFGFMLGSFCAKLYVDIGTVDLDSITINYKDSRWVGAWWLGFLVTGGVMLLAGIPFWFLPKSLTRQGEPESEKKPGAPEGGEQERFIPDNNKHNPPASKPAPVTMSAL---------------AKDFLPSLKKLFSNTIYVLLVCTGLIQVSGFIGMITFKPKFMEQVYGQSASRAIFLIGIMNLPAVALGIVTGGFIMKRFKVNVLGAAKICIVASVLAFCSMLIQYFLQCDNSQVAGLTVTYQGAPEVSYQTETLISQCNIGCSCSLKHWDPICASNG-VTYTSPCLAGCQ--------------------------------TSTGIGKE--MVFHNCSCIGEALLPYTNM--------------SAVLGQCPRKSDCDFMFKIYMAVTVIGAFFSAVGATPGYIILLRSITPELKSLALGMHTLIVRTLGGIPPPIYFGALIDKTCLKWGLKQCGGRGACRIYDSGAFRNAFLGLIYALYSSSYLLFGLLYNRLSHREKKQALKDQLKAPEQDSCGVSTTNGNASSAIVKCENPDQETTI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7C1-1", "uniprot_id": "A0ACD6B7C1_DANRE", "id": "A0ACD6B7C1-1", "name": "Solute carrier organic anion transporter family member", "aln": "----------------------------------------MSEPTIEDNGKPTSQQELCSPEAPEEPRCSSLKIFIGALSFAYFSKTLCGTYMKSAITQIERRFDLSSSAVGLVDGSFEMGNLLFVAVVSHFGARLHRPRLIGMGCFLMAIGSALTGLPHVFMGR-YKFDTAVQGF---ANETVVIAPCQYPTNPSEHS-IQHIDNTTGTDCVKDPGSSMWIYVFLGNALRGIGETPVTPLGISYIDDFAKAENSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDSVSITPQDARWVGAWWLGFFVSSAFLVLSGVPFWFLPRSLPKQGEEEKEIYN-----------TDDANKEHSVLQTTHTMTLADI---------------AKGFLPSLKRLLCTPAYFLLLCGIVLKFNSFIGLLTFKAKYMEQQFGQSASRANFLIGVLILPVVAVGIFLGGLLMKKYKLSVVAGAQLSFITSFTAFLLLLLHFGTKCDNVPVAGLTVSYNGTPYMPSDQRSLESQCNQDCSCSTSEWDPVCSDSG-ITYMSPCLAGCT--------------------------------ASTGQGKN--TVFHNCSCVLSPSPAEGGR--------------SVSLGQCPQGSACARSFTSYMAVSVLSSFINSLGTTPGYMIIIRCIAPELKSLALGIQTLVMRTLGGIPAPIYFGALIDTTCLKWGLKKCGGRGACRIYDSNMYRVIFLSLTTALSGCSYFFIIAVIVLLRRQFIKEEVKALQQMAGKQNEIELRSPEMQNPDGTKTDERDKNNTEG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58J631-1", "uniprot_id": "A0AC58J631_DANRE", "id": "A0AC58J631-1", "name": "Solute carrier organic anion transporter family member", "aln": "MVETAVSSAPEPGKHQAQPVSLSSDNSDPPAVQPPRVEPLPFKFIMEGSSNGMEYSDRNEKASSTTCCSPRLKIFICALAFCYFSKSMTASYTKSTITQIEKRFEITSSTVGFIDGSFEMGNMLVITLVSYVGAKFHRPKIIGAGVLLMGIGTLLMASPHFLMGR-YKYGTAATHTNDAGNFT-VISTCSSDSQETLQQPYSECQIIE------AESSLLWVVVLLGNAMRGIGEASIVPLGMSFIDDYARPENSAFYIGCLNTLRGIGPIFGFILGSLCANLYVDFDLVNQESVTITPQDSRWVGAWWLGFVVSGLLTLLAAFPFWFLPRALPENSQ--------------------TSELDHPSEQHKTTPSLTEI---------------IKDFAPTFKRLLTNKIYILYLAYSIVAFNDFAIVATYTPKYLEQQFGQSASKANFLIGVTCIPAVALGIFLSGLMMKRFKWGLLASARVNLFTGVTMLLLAVPFFALSCENLDVAGVTVPYQGSTEVQGVISDVLPSCNADCGCPDLQWDPVCGENG-VTYISPCHAGCN--------------------------------STQGAGWN--KTFHDCRCIQSWGLSVGNS--------------SAVLGQCSRDPNCNQMIYVFLGVQSLVLFVYSLGAVPFLTFSMRIVDPEMKALSVGVLLLSIRVLGGIPAPIYFGGLIDTTCLKWGQRKSCGRGACRIYDNETFRFLFQGMTIGLRVLACSVLWIATIEIKRKSAEQ----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NHT1-1", "uniprot_id": "A0A8M1NHT1_DANRE", "id": "A0A8M1NHT1-1", "name": "Solute carrier organic anion transporter family member", "aln": "---------------------------------------------MEGSTIGMEHSDRNQKTSQTKCCPPRLKIFIAALAFCYFSKSMTASYTKSTITQIERRFEIPSSTVGIIDGGFEMGNMLVITLVSYVGAKFHRPKIIGAGVLLMGIGTLLMASPHFIMGR-YKYGTAATHTNDAGNFT-VISTCSSDSQKTLQQPFSGCRKEE------AESSPLWVIVVLGNTMLGIGEASIIPLGMSFVDDYARPENSAFYIGCLNTIKGIGPIFGFVLGSLCANLYVDIGLVNKESVTITPQDSRWVGAWWLGYVVSGLLTVLAAFPFWFLPKALPENSQ--------------------ISLLDNTPQQHKTTPSLTEI---------------VKDFAPTFKRLLTNKIYILYLAYSIVAFNDFAILVTYTPKYLEQQFGQSASKANFLIGVTCVPAVALGVFLSGLMMKRFKWGLLASARVNLLTIVATVFLTVPFFALSCENLDIAGVTVPYQGSTEVQGVTSDVLPSCNADCGCPDLHWDPVCGENG-VTYISPCHAGCS--------------------------------STQGAGRN--KTFHDCGCIQSWGLSVGNS--------------SAVLGQCSQNPNCNRMMYLYLGLQSLALFVYSLGAVPLFTMSLRIVDPELKSLSVGVLLLSIRVLGGIPAPIYFGALVDSSCLKWGQRKSCGRGACRIYDIETFRFLFQGLTNCLRVLACSLLWIATIWIKRKIQNDKQISEDMELQRGPSDDPEHEDAVK----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "--------------------------------------MAEVKRRDPNRPPGHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDKTEDDCDDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP----TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLA----LRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFSMTQAGQLNLTS-----------NCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNATSKLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWT-KTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEEERANRKDQPITPLLAKKSEQE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W271-1", "uniprot_id": "Q9W271_DROME", "id": "Q9W271-1", "name": "Solute carrier organic anion transporter family member", "aln": "-------MTEERGKVDLEKSETLPFIEKPFAISDKERESAPENETEGEDGGKDTYCGFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTN----------QERDKKLCQPTAGGCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEP----TLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKR--------------RLQLKQDERKQSLPLNERS---------------------LADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCEGSDRLNTLTTLSAGN-----------SCSASCHCDYVHYAPVCSADN-ITFISACHAGCS---------------------------------ERTKDALGRTIYTGCECLGSSSLNSE--------------PESQFAVDGTCPVDCFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWG-KTCSNKGNCWLYDTKSMRYALNLSAAFFIFLGGFLNIAVWYHAKNLKIFDEEESSPKDSLKNKEVEMKTIDSNPE---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :*:*:.:.:. *:: . ::. :: .:.: ..: :**: :. * . : *.: * : :. .: : *:*:: .** :::** : ::. :. : * ..: :. . . ::: * :*.**:*****.:.: . . . : ::* . .: :. : . . :. . . : * :* : * : : * : . .:. .* ::.: * . * . . *. * * : *:* *: *.* *** : . . * : . : . . : : : *::. *. : *. * *: :* ::* *: * . .* * :*: : . . ", "identical_positions": 57, "similar_positions": 139, "identity": "6.99%" }, { "cls_id": "homologset.agr.HGNC:32935", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76M99-1", "uniprot_id": "S22AO_RAT", "id": "Q76M99-1", "name": "Steroid transmembrane transporter SLC22A24", "aln": "--------------MAFQDLIT-QIGCLGRFQILHLIFVLICFILVVPHTVLENFTAAIPSHRCWVPILDN-NTMSDNNSRILSQDDLLRISIPMDSNLRPE---KCRRYIQPQWDLLHLNGTFSTVTEPDT------EPCVDGWVYDQSTFLS-------------TTVTQWDLVCGSQTLNSVAKFIYMTGIFIGHLMGGHLSDKFGRKFIVTCGLLTLAVTETSVAFAPTFLIYCSLRFLTGISSSCIRTNSALLILEWTSPKFQAMVMALIFSAGGIGQVLLGVLAFGIRNWQHLQLAMSVPVFFLLIPTRWLSESARWLIITNKPQEGLKELIKVAHINGIKNSRDVLTLEVVKTTMKDELEAAETKPSPLVLFRTPNLRKRICLLSFVRCVSLISTVGLLINLQYLSNKVFLLQCLYG--VVCTPANLLGNFSMNYMGRRTTQIIFMSVMGISILS------ITFLTQEMQ------IPRLVLASLGGAISSASLTSTAVLSNELVPTVIRATALGVIGIFGSAGAALSPLLMILMTYSASLPWIIYGVLPILSSL-VVLLLPE--TRNQPLPDSIQDVENKRKSSREVKK-DAVAKVTPF----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCA0-1", "uniprot_id": "S22AJ_MOUSE", "id": "Q8VCA0-1", "name": "Solute carrier family 22 member 19", "aln": "--------------MAFQDLII-QIGSLGRFQILHMIFVLICHALSAPHTLLENFTAAIPSHRCWVPILDN-DTASDNGSRILSQDDLLRISIPLDSNLRPD---KCRRYIQPQWHLLHLNGTFPTVTEPDT------EPCVDGWVYDQSTFLS-------------TTVTQWDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDKFGRKLIFTCSLLKMAITETCVAFAPSFLIYCSLRFLSGIFSSTLRTNSALLILEWTSPKFQALVMALIFIASGVGQTLLGGLAFAFRNWHHLQLALSVPMFLLLIPTRWLSESARWLIMANKPQKSLKELKKAACVNRIKNSGDALTLEVVKTIMKEELEAAQTKPSPLDLFRTPNLRKRICLLSFVRFVSVMSLLGLLINIQYLSNNVFLLQCLYG--VVCIPANVLGNFSMNYMGRRMTQLIFMSVLGISILA------VVFLPQEMQ------ILRVFLSTLGGAISSASITSTLVHANELVPTIIRATALGVVGIAGSAGGALSPLLMILTTYSASLPWIIYGILPFLGGL-VALLLPE--TKNQPLPDSIQDIENKRKSSKEAKK-DVVAKVTPL----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70609-1", "uniprot_id": "O70609_RAT", "id": "O70609-1", "name": "", "aln": "--------------MAFQDLLN-QVGSLGRFQILQMTFILIFNIIISPHSLLENFTAVIPNHRCWVPILDN-DTVSGNDNGNLSQDDLLRVSIPLDSDLRPE---KCRRFVQPQWDLLHLNGTFSSVTEPDT------EPCVDGWVYDQSTFLS-------------TIITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICASLQMAVTETCAAFAPTFLIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLCAGAIGQTVLAGLAFTVRNWHHLHLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGMKNSTDVLTIEVVRTIMKEELEASQTKSSLWDLFRTPNLRKRICLLSLVRFVVWLSVIGLLINFQHLRINVFLLQCLLG--IITIPANLVGIFLVNHLGRRISQLFIISLFGISILA------IIFVPQEMQ------ILRMVLATFGGVFSFVSVSSALVHANELLPTIIRATALGVIGIAGSTGAALSPLFMILRTYSDSLPWIIYGVLSFLGGL-VVLLLPE--TKNQPLPDSIQDVENEGRASRQGKQNDTLIKVTQF----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76M72-1", "uniprot_id": "S22AR_MOUSE", "id": "Q76M72-1", "name": "Solute carrier family 22 member 27", "aln": "--------------MSFQELLN-QVGSLGRFQILQIVFLLLLNAIVVPHIAMENFTAAIPNHRCWVPILDN-DTASDNGSRILSQDDLLRISIPLDSNLRPE---KCRRFAQPQWHLLHLNGTFSNVSEPDT------EPCVDGWVYDRSNFLS-------------TIVTEWDLVCESQALNSVTKFSFMIGLFIGGIICGHLSDRLGRKFILTCALLQFAITETCVAFAPSFFIYCSLRFLAGLSVEPILVNSHLLMLEWTSPKFLTMMAALLSCAPNIGYMISAGLAFLFRIWHHLQLTMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGD-LTMEIVRTSMKAELEAAKTKPSLRDLFHTSILRKRICVLSFMRLFFTVSIFGLAVHLQHLSSNIILLQFLIS--ALAILVSVIGPFVLNHIGRRITYLVLMSLRGIFILI------AVFVPQEMQ------TLRIIMATLAEGISSLCVGVSRLHTNELLPTTLRATAVGVIGFFGNSGSFLSPLFMLLATYYANMPWIFYGGFSIFNAF-TVFLLPE--TKNQPLPDSTHDVGNDWKESRKGKKEDPIIKVTRF----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6T423-1", "uniprot_id": "S22AP_HUMAN", "id": "Q6T423-1", "name": "Solute carrier family 22 member 25", "aln": "--------------MAFQDLLD-QVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFILDHRCWVHILDN-DTIPDNDPGTLSQDALLRISIPFDSNLRPE---KCRRFVHPQWKLIHLNGTFPNTSEPDT------EPCVDGWVYDQSSFPS-------------TIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSFVRFASTIPFWGLTLHLQHLGNNVFLLQTLFG--AVTLLANCVAPWALNHMSRRLSQMLLMFLLATCLLA------IIFVPQEMQ------TLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFAILSGL-VVLLLPE--TRNQPLLDSIQDVENEGVNSLAAPQRSSVL---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDS2-1", "uniprot_id": "Q9VDS2_DROME", "id": "Q9VDS2-1", "name": "", "aln": "--------------MKKDNLYRGWMPNIRRNSPAPLDLGHMAHSFTCTDPKANEVSPQTPHPKANNLADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRKFLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGLGTCCLVTR--DKEQPPVGAVVNKGQQLIAFT------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDR9-1", "uniprot_id": "Q9VDR9_DROME", "id": "Q9VDR9-1", "name": "Solute carrier family 22 member 3", "aln": "MTDSQSMGSIPRKSSPELDVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQ----SSLPCEHVEHRTDYKS--------------LISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYN---NRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRS----QLVYIHLIWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTR-RHWRWAGNLMIIAGLSTYLIWLLPETER-NSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNTYRRQSAIILRRCSTVSSDCSAYSNELLSNFERNMAVSIADIWHINFHPSSEIEMEVEQSGPEAHRAHSSETI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * . : : : :. : : : * : . .. . .: : ::**:* : : :: . * ::* :. : : . . .:. :: :* *:. : .. :: : : * :* :: : : :: . :.:. * .::.** : : : : . .:. . :* : : :: : * . : : : .. :. : :: :: ::.: :.: : .*::. * . ..:: * :. : : .: * :** . ", "identical_positions": 22, "similar_positions": 120, "identity": "3.34%" }, { "cls_id": "homologset.agr.HGNC:32940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43688-1", "uniprot_id": "NKX26_MOUSE", "id": "P43688-1", "name": "Homeobox protein Nkx-2.6", "aln": "MLSSPVASTPFSVADILRLECQQKDSKTLSQWELHRNPVKPRYLRMNQESGWFESSD---------RAQAVPFRCTWETVLEMGSNPVGEPQTPPGTISRLGARNPMTDRGVGNLSGDMRRGGPVSTRTRPQRKSRVLFSQAQVLALERRFKQQRYLTAPEREHLASALQLTSTQVKIWFQNRRYKSKSQRQDQTLELAGHPLAPRRVAVPVLVLDGKPCLDPD--VAAFLGPY-KATSPYSCFGGYAGTPYDASYASRCTSASAGPGPLTPLASSGFSPGGQSAAPQGHLPATPQGVTAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EZF0-1", "uniprot_id": "F7EZF0_RAT", "id": "F7EZF0-1", "name": "", "aln": "MLRSPVASTPFSVEDILRLEYWQKDSKTMSQWELHRNTVKPQYIRMNPESGRSESFDT-------VQTEATPFLCTWETVLEMDSNLVREPKTPPGTISPLGVENLMMEHGVGNRSDDPRRAGPVPTVTRPRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASVLQLTSTQVKIWFQNRRYKCKRQRQDQTLELAGHPLAPRRVAVPVLVLDVKPCLDPD--RHAFPSPY-ATTVLYSCFSSYTGTPYSASYAGRYT--GAGPGPLAPLASSGFSPGGQSAAPQGHLAATPQGVTA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NCS4-1", "uniprot_id": "NKX26_HUMAN", "id": "A6NCS4-1", "name": "Homeobox protein Nkx-2.6", "aln": "MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ***:****** ****** :. . : .: .:::.. : :*:**: *. * : : * . *:****.:: : **:. .: * ** . : ::**** ... * . . . :* :**.**********************:*********.******************.* ****::********:********** * ****.*. ** .** :. ***:..*:*:**.*.*. : :**.* :****:**. ***.*:*****.** *** * ", "identical_positions": 156, "similar_positions": 71, "identity": "51.83%" }, { "cls_id": "homologset.agr.HGNC:32942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERS8-1", "uniprot_id": "SEBOX_RAT", "id": "Q9ERS8-1", "name": "Homeobox protein SEBOX", "aln": "------------------------------MASPVEASPG-CASGL---------GPHRRKRTTFSVGQLLELERVFAARPYPDISTREHLAQITHLPEAKIQVWFQNRRAKRIKDRKPGALNARLELPPN-CSLPDTP-----------------------QLSWDPGTPSHPLHS---------TSSAQQTSACPPQTSCLAPILG---PGQS---WSG-AKAAAPWG------TSEVSGVHS-LEQIVP-------------------QTSLGNLSDLIYTSAIVTNVDHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70368-1", "uniprot_id": "SEBOX_MOUSE", "id": "P70368-1", "name": "Homeobox protein SEBOX", "aln": "------------------------------MASPVEASPG-CASGL---------GPHRRKRTTFSVGQLVELERVFAARPYPDISTREHLAQVTHLPEAKIQVWFQNRRAKRIKDRKPGALNSRLELPPNSCSLPDTP-----------------------QLPWDPGTSSHPLHP---------TSSAQYTSACPPQTSCLGPILG---PGQS---WSG-AKVAAPWG------TSGASGIHSSLEQIVP-------------------QTSLGNLSDLIYTSAIVTNVDHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB31-1", "uniprot_id": "SEBOX_HUMAN", "id": "Q9HB31-1", "name": "Homeobox protein SEBOX", "aln": "------------------------------MPSPVDASSADGGSGL---------GSHRRKRTTFSKGQLLELERAFAAWPYPNISTHEHLAWVTCLPEAKVQVWFQKRWAKIIKNRKSGILSPGSECPQSSCSLPDTL-----------------------QQPWDPQMPGQPPPS---------SGTPQRTSVCR-HSSCPAPGLS---PRQG---WEG-AKAVAPWG------SAGASEVHPSLERATP-------------------QTSLGSLSDLIYALAIVVNVDHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JJ26-1", "uniprot_id": "SEBOX_DANRE", "id": "Q8JJ26-1", "name": "Homeobox protein SEBOX", "aln": "MALFYDQSFDLGLVQKINMETESDFIFNTNMLQFTDVTTKHMLSSPELDRTGHVEGQRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESKIQVWFQNRRARSMKSKKLITPVSR-RSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLIRQALNPWPQNRPPISPDLPEILQWANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQMNCFAAHPEGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQRQALTHYPQTSLGDISDLIYKAAVVTNLEEC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:.:. *. * ::**** ** .** ****.* ***:*: :*:** :* ***:*:*****:* *: :*.:* . . * . *::* * : . :* .:* . :. . *. :** . : * *. *. . .. * * :: . ::: * *****.:***** *:*.*::. ", "identical_positions": 65, "similar_positions": 59, "identity": "22.11%" }, { "cls_id": "homologset.agr.HGNC:32947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A306-1", "uniprot_id": "D4A306_RAT", "id": "D4A306-1", "name": "RING finger protein 207", "aln": "MSGAIFAPLEGLGALDAASGHPLVCPLCHTQYEHPCLLDCFHDFCAGCLRGRATDGRLSCPLCQHQTLVKGPSGLPPADRLLQFLVDSSGDGIEAVHCANCDLECSKQDAETTYFCNTCGQPLCARCREETHRARMFARHDIVALGQRSRDFIQKCKLHSEPYIVFSTDKKSLLCIRCFRDMQGESRAHCVDLESAYVQGCERLEQAVLAVKALQTATKEAIALLQAMVEEVRHSAAEEEAAIHALFGSMQDRLAERKALLLQTVQSQYEEKDKAFKEQLTHLASLLPTLQVHLVICSSFLSLASKAEFLDLGYELMERLQGIVTRPHRLRPAQSSKIASDHRAEFARCLEPLLLLGPRRAVSTVGGANTLAGGSSPKVLKTQ--SCPSPVG---KMSGSPVQKPSPHRFISTKVLLAEGEDTPFTEHCRHYEDSYRGLQLEVQNLKDQVQELHRDLTKHHSLIKAEIMGDILHRSLLLDTRIASEYASMEGMRAIFQEIWEDSYQRVATQQEIYEAQLHDLLQLKQENAYLTTITKQITPYIRSIARVKERLEPRFQGP---VAEHSEHRQNLYDET-----PARTDPGCTTEKRDKASEPSGSSWALSGLPEGPSLNNQDHLRP-KLEAGDEG--WRAGSGSKGACYQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V3A7-1", "uniprot_id": "RN207_MOUSE", "id": "Q3V3A7-1", "name": "RING finger protein 207", "aln": "MSGAIFAPLEGLSALDAASGHPLVCPLCHGQYERPCLLDCFHDFCTGCLRGRATDGRLSCPLCQHQTLVKGPSGLPPVDRLLQFLVDSSGDGSEAVRCANCDLECSQQDAETTYFCNTCGQPLCARCREETHRARMFARHDIVALGQRSRDVIQKCTLHSEPYIMFSTDKKSLLCIRCFRDMQGESRAHCVDLESAYVQGCERLEQAVLAVKALQTATKEAIALLQSMVEEVRHSAAEEEAAIHALFGSMQDRMAERKALLLQTVQSQYEEKDKAFKEQLTHLASLLPTLQVHLVICSSFLSLASKAEFLDLGYELMERLQGIVTRPHRLRPAQSSKIASDHRAEFARCLEPLLLLGPRREVSTVGGANTLSGGSSPMVLKTP--SCPSPVG---KMSGSPVQKPSPHRFISTKVLLAEGEDTPFTEHCRHYEDSYRGLQVEVQNLKDQVQELHRDLTKHHSLIKAEIMGDILRRSLLLDTQIASEYASLEGRRAIFQEIWEDSYQRVATQQEIYEAQLRDLLQLRQENAYLTIVTKQITPYIRSIARVKERLEPRFQVP---VDEHAEHGQNMYDET-----PGRTDPGCTTEKRDKASEPNGSSWSLSSLPEGPSLKNQDHLRP-KLEAGDEG--WRAGSGSKGACYQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZRF8-1", "uniprot_id": "RN207_HUMAN", "id": "Q6ZRF8-1", "name": "RING finger protein 207", "aln": "MSGAIFGPLEGPSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCGQPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCLEPLLLLGPRRVAAAASGANTLAGGLGPKALTGP--HCPSPVG---KMSGSPVQKPTLHRSISTKVLLAEGENTPFAEHCRHYEDSYRHLQAEMQSLKDQVQELHRDLTKHHSLIKAEIMGDVLHKSLQLDVQIASEHASLEGMRVVFQEIWEEAYQRVANEQEIYEAQLHDLLQLRQENAYLTTITKQITPYVRSIAKVKERLEPRFQAP---VDEQSESLQNTHDDSRNNAASARNNPGSVPEKREKTSEPKGNSWAPNGLSEEPLLKNMDHHRS-KQKNGGDVPTWREHPT--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QHE3-1", "uniprot_id": "RN207_DANRE", "id": "E9QHE3-1", "name": "RING finger protein 207", "aln": "MSGEIFYSVDNLYDLDSANCHPLVCHLCQEQYEHPCLLDCYHTFCASCLRGRVADSRLTCPVCGHQSVVKGINALPPEDRLLKFLVDSSADSEETVQCANCDLECKKQDVDAMYYCNTCCQPLCRDCRETTHKAKMFSRHEIVSLAKRTKEAHKKCALHEEFYIMFSTEKKSMLCINCFRDMQVESRAHCIDIETAYIQGCEKLDQAVLAVKELQMSAREAIILLKAMIGEVRANVDEEESAICTLFSNMQEKLAERKKILLKAARSQHEEKERTFKEQLSHLAALLPTLQVHLVTCSAFLSSANKFEFLDMGYQLMERLKKIVKLPHRLRPTQSSKINTEYRSEFARCLEPLLLLGQRRSMSTTGSVALALGNASGLMQSSLSVQCHSPAMSDMSLCSSVVRRPTSHRYISTKVLLAKGGETPFMEHCCNYENSYRTLQTEIQKLKDQVQEIHRDLTKHHSLTKPDSMSEILEKSVQVDSQISSEYASVELMRAMFEEIWEETLQRVANEQEIYEAQLHDLLQLKQENSYLTTISRQIGPYIRSIAKVKERLEPRLKEPKELKDDRTEIMLKLYEDS---------TSTADTQPSNELSCNTEDNWTLNSLSEETNPKNKDYYRTNKQKNTTDSTNRKEIPM--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IKW1-1", "uniprot_id": "A0A0R4IKW1_DANRE", "id": "A0A0R4IKW1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLCLSLSLSEMPFG------------------------------------RRPTFHRHICTKVLLAEGRESPFTEHCRNFEKSYRSLQTEIQRLKDEVQEMHRDLTKHHSLINTDTMNEILERCLLIDEQIASQYSAVQTQRTVFEEKWDVTFQRVTNEQEIYEAQLHDLLQLKQENSYLTTIARQIGPYILSIAKVKERLEPRFQKP---ENDCIDTTVKIHEDQ---------------ISCKKKSCSDRDSDSSLILPPD------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *. . . ::*: ** *.******:* ::** *** ::*.*** ** *:* ***:***:********** :.: *.::*.:.: :* :*:*:::::: *.:*:* *: : ***:.:********:*****:***:*** :::** **: ***:********:: * : : : ::: .: * .. : *. ", "identical_positions": 91, "similar_positions": 66, "identity": "13.98%" }, { "cls_id": "homologset.agr.HGNC:32949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B4V4-1", "uniprot_id": "A0A8I6B4V4_RAT", "id": "A0A8I6B4V4-1", "name": "", "aln": "-MAFCRLPAWSSQTVR--------WFPKAAISCLPWEAAMAFPHLQQPSFLLASLKADSINKPFAQRCQDLVKVIEDFPAKELHAIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYSIAMEFLDPSGPMMKLVYKLQAEDYNFDFPVSCLPGPVKASIQENVLPDSPLYHNKVQFPPTGGLGLNLALNPFEYYMFYFALSLIS----QKPMPMSFHVRTSDCAYFILVDRYLSWFLP--TEGSVPPPLCSS---------PGGSSPSPAPRTPAMP---------FASYGLH-TSLLKRHISHQT-SVNADPASHEIWRSETLLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLNVSSALHSPAQPSLQALHAYQESFMPTEEHVLVVRLLLKHLHAFANSLKPD--QASPSAHSHATSPLEEFKRAAVPRFVQQKLYVFLQHCFGHWPLDASFRAVLEMWLSYLQPWRYAPEKQAQGSDSQPR--CVSERWAPFIQENLLMYTKLFVSFLNRALRTDLVSPKNALMVFRVAKVFAQPNLTEMIQKGEQLFLEPELIIPHRQHRLFTA---TSSFLSPWPPVVTDASFKVKSHVYSLEGQDCKYTPMFGPEVRTLVLRLAQLITQAKQTAKSISDQCVESPTGRSFLSWLGFGSTDTNSWYPANDPDEMGQDSIRKTDEYLEKALEYLRQIFRLSEAQLAQLTLALGNARDENG-KQQLPDCIVGEEGLILTPLGRYQIINGLRRFEIEYQGDLELQPIRSYEITSLVRALFRLSSAINRRCAGQMAALCSRNDFLGSFCRYHLTEP-ALSNRHLLSPVGRRQVTTPARGPRLSLRFLGSYRTLLLLLMAFFVASLFCIGPLPCSLLLVLGYILYAIAMTLLTERGKLHQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPR5-1", "uniprot_id": "NSMA3_MOUSE", "id": "Q6ZPR5-1", "name": "Sphingomyelin phosphodiesterase 4", "aln": "---------------------------------------MAFPHLQQPSFLLASLKADSINKPFAQRCQDLVKVIEDFPAKELHAVFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYSTAMEFLDPSGPMMKLVYKLQAEDYNFDFPVSCLPGPVKASIQENVLPDSPLYHNKVQFPPTGGLGLNLALNPFEYYMFYFALSLIS----QKPMSMTLHVRTSDCAYFTLVDRYLSWFLP--TEGSVPPPLCSS---------PGGSSPSPAPRTPAMP---------FASYGLH-TSLLKRHISHQT-SVNADPASHEIWRSETLLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLTVSSALHSPAQPSLQALHAYQESFTPTEEHVLVVRLLLKHLHAFANSLKPD--QASPSAHSHATSPLEEFKRAAVPRFVQQKLYVFLQHCFGHWPLDATFRAVLEMWLSYLQPWRYAPEKQAQGSDPQPR--CVSEKWAPFIQENLLMYTKLFVSFLNRALRTDLVSPKNALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELIIPHRQHRLFTV---TTSFLSPWPPVVTDASFKVKSHVYSLEGQDCKYTPMFGPEIRTLVLRLAQLITQAKQTAKSISDQYVESPTGRSFLSWLTFGLTDTNSCYPANDLDEIGQDSIRKTDEYLEKALEYLRQIFRLSEAQLAQLTLALGSARDENG-KQQLPDCIVGEEGLILTPLGRYQIINGLRRFEIEYQGDLELQPIRSYEITSLVRALFRLSSAINRRFAGQMAALCSRNDFLGSFCRYHLTEP-ALSNRHLLSPVGRRQVTNPARGPRLSLRFLGSYRTLLLLLMAFFVASLFCIGPLSCSLLLVLGYVLYAIAMTLLTERGKLHQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXE4-1", "uniprot_id": "NSMA3_HUMAN", "id": "Q9NXE4-1", "name": "Sphingomyelin phosphodiesterase 4", "aln": "MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSFLLASLKADSINKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYSIVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTPTGGLGLNLALNPFEYYIFFFALSLIT----QKPLPVSLHVRTSDCAYFILVDRYLSWFLP--TEGSVPPPLSSS---------PGGTSPSPPPRTPAIP---------FASYGLHHTSLLKRHISHQT-SVNADPASHEIWRSETLLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPSLQALHAYQESFTPTEEHVLVVRLLLKHLHAFANSLKPE--QASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFLQHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPR--CVSEKWAPFVQENLLMYTKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQHRLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLITQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENG-KKQLPDCIVGEDGLILTPLGRYQIINGLRRFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHLTEP-GLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCTLLLTLGYVLYASAMTLLTERGKLHQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFJ7-1", "uniprot_id": "NSMA3_DANRE", "id": "Q6PFJ7-1", "name": "Sphingomyelin phosphodiesterase 4", "aln": "---------------------------------------MAASALQQPSYLLANLKADWTNKPLHQRCHELCKIIDDYPAKELHAIFPWLVECVFGSLDGILTGWNLRFLQARS--AEYSIAMEFLDPSGPMMKLVYKLQAEEYKYEFPISYLPGPIKSSIHAGVLPDCPLFHNKIQFPMSG----LLFLNPFEYYMFNFASSLIA----PKNYPQGQHGSSSDSAYFVLVDTYLKYFLP--TEGNVPPSPFSD---------TRGTVASPAPRSTNVP---------YVGYGGHSTSLLKRHITHQS-SVNADPAAQEIWRSETLLQVFVEMWLHHYSLEMYQKLQSPQVK-----------------------------EPFMPSEEHVLVVRLLVKHLHTFSSSLKPESISSSPSAHSHS-SPLEELKRVVVQRFVQQKLYVFLQHCFGHWPLDASFRAVLETWLSYIQPWRYTGDKNNTQTDGPNR--TVPDKWASFVQENLLLYTKLFQGFLNRAMRTDLVNAKNALMVFRVAKVFAQPSLSEMIQKGEQLFLEPEHAILQRHNRVFLTPSHGGSFLSARQPMGTDNVFKVKSHVYSLEGQDCQYNLMFGPDQRKNVLKLIQIIAQARQTAKRISDHSTEMAANNSFLSWFGVGSPDHNSTFTGGEMDEMGGEGVKKTHEFLDKALDYLCQIFRLNAGQLSQLISNVASVDNNGA-SKQLPDCIPSENGLVLTDLGRLQIINGLRRFEIEYQGDPELQPIRSYENAFLVRLLFQISSFINERLGEHMEVLCSRQDFLGSVGRHYLSSSSAVVEQRRKSPVTRQMRDRPQR-ARLSLRALASYRTLLTLLLLYMLFALLSFGLFSSTGLILIISFLYELLSNFFHEKLKTH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH0-1", "uniprot_id": "Q9VGH0_DROME", "id": "Q9VGH0-1", "name": "Sphingomyelin phosphodiesterase 4", "aln": "------------------------------------------MSQTMPPENLSSRLLTVLSLPLFERVHELSILFDRCSLRQVQEIFPHVVHSIFG-IDGNPLGWGLRTTTLENNPVQFQTLHQFFGVCGPLMHVCHRLLVDQYKFELDINLLPAKFVSLLQNGQNPS--FYAELINVETMMHQVSTLSLNAFDFYVIHFVLYALQPLHSINPIAMQIHNVRSKTVYLKLVAEYLNNFLPLLPDARIEPVHFSSGVKAPQPLPAQALQPQRQPRYIKIPSSYRNGGNVSGGGGIPSASVGVGNISPQSNSPSASSNRAYAWRSESVLHFFVDIWLR-YDIES---------------------------------------EHHLPSSDFVRGVRTLVKQVHFFAN------------GAQHDHSSLCALRKVSLS-MVKARIYAFIVGLIDRWPLDSSLMVVLELWLSYIQPWRYTIASLNNKTPSLSYRPPISSCFDGFIIDNLIMYTHIFMQLLPHFGRLDYTVYRNAFMLYRLATIFSQHDLVDKLQRFEAIHAGNSFGFDSPQRQVNIMN----------KSVSPGTPWNQAVNISSAK----LFSYTMQTQMETFLLLISMARNSVLRDIAKLRNEIAERQRSEGFLKNF------YKKIFGECTQEEVTLREFSRIPEVLRQCIDAFCRTFNVDQANLSMHETLPEEPSVPSAPAVQNFSFFDASDTLDTSKLNPHQMS--LNASSLHAAVDPATLPIQTNEVRALVRMLHFVSEKINNKYGSQLQGFYVRDDYFGKVARQLLYAP--MTEQWFDKSSGHVEICENLVPPRVCLRPLGSIPALTTIGCSMIFGQLVWGAPLLGIFILATVLLVYIMLQALFS--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *:. . *: :: ::* ::: . :::: :** :*..:** :** **.** . .::. :*:. **:*:: ::* .::*:::: :. **. . : :: *. :: : ::. * **.*::*:: *. : : . * *. .*: ** **. *** .:. : * *. . . .. ** :* . * :*: :*: *: * .*.. ****::*:.**::**: *.:* * . *:.:.* ** *:*::* *:. . .* *.* :::. : :*: ::* *: :.:****::: .*** ****:*****: . : :.. : *: :**::**::* :* : * * . ::*:*::*:*.:*:* .* : :*: * :. . : :.:: . .. :: :: * : :. : .: .. :* : .. : : :. .* ...**. : : : :*: . : * * :.:: : : *.:. .:* .. * . : ..: * : *. *: *. .:. * **:: * *** *. :*. **.: . :: : *:*::*.. * * . : .: .. : .*:.** *.* :* : :. *. . : :: .:* :: ", "identical_positions": 150, "similar_positions": 267, "identity": "16.72%" }, { "cls_id": "homologset.agr.HGNC:32950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKN9-1", "uniprot_id": "D3ZKN9_RAT", "id": "D3ZKN9-1", "name": "", "aln": "------------------------------MAPQQTGSRKRKASEVEQGAGTSSSPGRAA--AAAGTGQADGPLLLAKRPRRPVARRSVVHYLKGRALGAYGHPGLVGFEGDLRSYGVLRLPELLRERQLALGPLNKVFASQWLNARQVVCGTKCNTLFVVDVQTGRITRIPLLRDRGPGQTRAQPTCGIHAIQLNPSKTLLATGGENPNSLAVYQLPTLDPVCLGDRQGHRDWIFAIAWMSDTVAVSGSRDGTVALWRVDPDMFNGSIQGWHNNSGIPRYSHIRPRDMEAIPRATTNPGNRKVRALAFSGRNQELGAVSLDGYFHLWKARSSLSRLLSLRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIKPLCSREGGTGVRSLSFYHHIITVGTGHGSLLFYDIRAQKFLEERASANPDSFLGRTGRKLKLTCGRGWLNQDELWVNYFGGTEEFPNALYTHCYNWPEMKLFVGGGPLPSGLHGNYAGLWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGW4-1", "uniprot_id": "DC122_MOUSE", "id": "Q8BGW4-1", "name": "DDB1- and CUL4-associated factor 12-like protein 2", "aln": "------------------------------MAPQQTGSRKRKASEVEQGAGTSSLPGRAA--AAAGTGQADGPLLLAKRPRRPVARRSLVHYLKGRALGADGHPGVAGFEGDLRSYGVLRLPELLRERQLTLGPLNKVFASQWLNARQVVCGTKCNTLFVVDVQTGRITRIPLMRDRGPGQTRAQPTCGIHAIQLNPSKTLLATGGENPNSLAVYQLPTLDPVCLGDRQGHRDWIFAIAWMSDTVAVSGSRDGTVALWRVDSDMFNGSIP-WHNNSGIPRYSHIRPRDMEAIPRATTNPGNRKVRALAFSGRNQELGAVSLDGYFHLWKARSSLSRLLSLRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIKPLCSREGGTGVRSLSFYQHIITVGTGHGSLLFYDIRAQKFLEERASASPDSFLGRTGRKLKLTCGRGWLNQDELWVNYFGGTEEFPNALYTHCYNWPEMKLFVGGGPLPSGLHGNYAGLWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CBW4-1", "uniprot_id": "DC121_MOUSE", "id": "Q8CBW4-1", "name": "DDB1- and CUL4-associated factor 12-like protein 1", "aln": "MRQADSQTQPSPAEQETPQPAGPSNRSPPTMGPQQTGSRKRKAAEVDQGAGTSSSPGPAAPMATAGEGNAEGSMLLTKRPRRPVAHLSMVNYLKGRALGADGHPGLAGFEGDLRSYGVLRLPELLRERQLTLGPLNKVFASQWLNARQVVCGTKCNTLFVVDVKTDHIMRIPLMRDRVPDLSRGPPSCGIHAVELNPSKTLLATGGENPNSLAVYQLPTLDPVCLGDCQGHRDWIFAIAWMSDTVAVSGSRDGTVALWKVDPDMFNGSIA-WHKDAGLPVYAHISPTDMEAIPKATTNPGNRKVRALAFSNKNQELGAVSLDGYFHLWKARSSLSRLLSLRLPYCRENVCLTYCDEFSLYAVGSQSHVSFLDLRQGQQNIPPLCSREGGTGVRSLSVHQHIVTVGTGHGSLLFYDIRAQKFLEERSAANPDMFPVPSGRKLKLTCGSGWINQDDLLENYVAGVEDFPNALYTHCYNWPEMKLFVGGGPLASGLHGNYAGLWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VW00-1", "uniprot_id": "DC122_HUMAN", "id": "Q5VW00-1", "name": "DDB1- and CUL4-associated factor 12-like protein 2", "aln": "------------------------------MAQQQTGSRKRKAPAVEAGAGSSSSQGLAA---ADGEG-----PLLPKKQKRPATRRRLVHYLKGREVGARGPAGLQGFEGELRGYAVQRLPELLTERQLDLGTLNKVFASQWLNARQVVCGTKCNTLFVVDVQSGHITRIPLMRDKEAGLAQAHQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPTLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDMFNGSIA-WHSEVGLPVYAHIRPRDVEAIPRASTNPSNRKVRALAFSGKNQELGAVSLDGYFHLWKARSTLSRLLSIRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIRPLCSREGGTGVRSLSFYQHIITVGTGHGSLLFYDIRAQKFLEERASSSLDSMPGPAGRKLKLACGRGWLNQDDVWVNYFGGMGEFPNALYTHCYNWPEMKLFVAGGPLPSGLHGNYAGLWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGE3-1", "uniprot_id": "DCA12_DROME", "id": "Q9VGE3-1", "name": "DDB1- and CUL4-associated factor 12 homolog", "aln": "------------MFNGMVRTIRDSVVGTYPSCHVSSRLEERRAKQRAMRQERRRKPDKPDD-FVTYEDSGSDEETPQQQEEVLNTSYNLCDYLRSRESGLRDRRSVN---VEYTSRYVLTH-DMLRETQISLGYINKVFCSKWLSSRQVVFGTKCNKLLVYDVNMRRVDAIPTLSNSRANHPEVQG--GLHAIELSPSRSFLATGARNSSDIAVYRLPTLDPVCVGE-GGHRDLIMGMCWLDDQFLVSGSKDSRMALWRINEDHMEFPDG---GEEACPTFATIHPLSVKEVRTAQR------IRSLCFNKEFKEIAALSLNGYIHIFNAET-FKQTLSRKLPNCQDNVSIAYHSDG-LYAVGCRSYTILLDAR-TLQTIKKITSRYSGCGIRATSFEGNLLTVGTGLGMLLFYDIRAGKYLESSVNAS---------RTVALKCSKGIVYPEDEMDG-FQQVKYVP-AIYTHCYDSTRMRLFAAGGPLPATLVGNYAGVWQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .:*:* . . . . :: . : : .**:.* * . .: : . * ::* * *: ** :****.*:**.:**** *****.*:* **: :: ** : : .. .. *:**::*.**:::****..*...:*:*:******:*:*: **:* *:.:.*:.* . ****:*. :***::: * :: . : . * :: * * .:: : * :*:*.*. . :*:.*:**:**:*:::*.: :.: ** :** *::**.::* .: *****.:*:. :** * *.* : ** .* *:*: *. :::***** * ******** *:**. :. *.: * *. * : :: . . .* *:*****: ..*:**..****.: * *****:*.", "identical_positions": 152, "similar_positions": 149, "identity": "30.28%" }, { "cls_id": "homologset.agr.HGNC:32951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LXL3-1", "uniprot_id": "F1LXL3_RAT", "id": "F1LXL3-1", "name": "", "aln": "VLKTLNISVFSDLKVLSNMKPASAFLLLISLACLFLS-VDAVSQGG-FQAFCNNYEKTLATDGKSCPKIHKP--VCGTDGKTYQNRCEF-CQTAMERSVG-KLGFKHEGKC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D256-1", "uniprot_id": "ISK12_MOUSE", "id": "Q9D256-1", "name": "Serine protease inhibitor Kazal-type 12", "aln": "------------------MKPAGAFLLLISLACLFLS-VDAVSQGG-FQAFCSNYEKTLAPDGKSCPKTHKP--VCGTDGKTYQNRCAF-CQTAMERSLG-KLGFKHEGKC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5DT21-1", "uniprot_id": "ISK9_HUMAN", "id": "Q5DT21-1", "name": "Serine protease inhibitor Kazal-type 9", "aln": "------------------MRATAIVLLLALTLATMFS-IECAKQTK-QMVDCSHYKKLPPGQQRFCHHMYDP--ICGSDGKTYKNDCFF-CS-KVKKTDG-TLKFVHFGKC----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKE7-1", "uniprot_id": "Q9VKE7_DROME", "id": "Q9VKE7-1", "name": "Kazal-like domain-containing protein", "aln": "------------------MKYLTLLLVLGLLIALFAG--SSEG------SYCP------------CDLKTKGTQVCGSNGVTFKNRCEFECSQRDYKKLGRTLNIRKDGPCNETN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PBA3-1", "uniprot_id": "M9PBA3_DROME", "id": "M9PBA3-1", "name": "Kazal-like domain-containing protein", "aln": "------------------MKFLSILVALCLLLALTISPISCDDTEKVVRPICP------------CPRNYEP--VCGSNLVTYPNRCEFDCVRRNVERQGRSMGLLRDGTC----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .: * . . .. * * . :**:: *: * * * * . * .: : : * * ", "identical_positions": 14, "similar_positions": 17, "identity": "12.17%" }, { "cls_id": "homologset.agr.HGNC:32954", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAC7-1", "uniprot_id": "TTC32_MOUSE", "id": "Q9DAC7-1", "name": "Tetratricopeptide repeat protein 32", "aln": "MALRPGREGGESSAALATAQARFSRGEFAEARELYSAFIGQCARHG-------SKCSPEDLATAYNNRGQTKYFSVDFYEAMDDYTSAIEILPSFEVPYYNRGLIRYRLGYFDEALEDFKKALDLNPGFQDAVLSLKQTILDKEEKQRRNAEKSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RDE8-1", "uniprot_id": "M0RDE8_RAT", "id": "M0RDE8-1", "name": "", "aln": "MAVPRGRERGESPAALAMAQARFARGDFTEARELYSAFIGQCASHR-------SKCSPEDLATAYNNRGQTKYFSVDFYEAMDDYTSAIEILPNFEVPYYNRGLIRYRLGYFDEAVEDFKKALDRNPAFQDAVLSLKQTILDKEEKQRRNAQKSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5I0X7-1", "uniprot_id": "TTC32_HUMAN", "id": "Q5I0X7-1", "name": "Tetratricopeptide repeat protein 32", "aln": "---MEG-QRQESHATLTLAQAHFNNGEYAEAEALYSAYIRRCACAASSDESPGSKCSPEDLATAYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKKVLDLNPGFQDATLSLKQTILDKEEKQRRNVAKNY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TYX3-1", "uniprot_id": "Q5TYX3_DANRE", "id": "Q5TYX3-1", "name": "", "aln": "-------MENSELKILQKAHEEFNSKNYKRAEELYTQFIESCTKSR--------DCNGQDLAIAYNNRGQVKYLRVDFYEAMDDYTSAIHINRQFEVPLYNRGLIRYRLGFFKEAEGDFRRVLELNPDFKDAKESLNQTLLDREEKVKR----GY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * *: .* :: .*. **: :* *: .*. :*** ******* **: **************.: .**** ****** ****:*.:* **::.*: ** *:** **:**:**:*** :* .*", "identical_positions": 70, "similar_positions": 31, "identity": "45.16%" }, { "cls_id": "homologset.agr.HGNC:32958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LBQ6-1", "uniprot_id": "A0ABK0LBQ6_RAT", "id": "A0ABK0LBQ6-1", "name": "", "aln": "--MAGELSQEALLDFLCQAGGRVRNAELLSHFKSFLRDPHVPSGQLQERRELFKGFVNSVAAVRQDPDGTKYVVLKRRYRDLLGEEGLQRP------APTDQ-----QPRSHRRLDP------------EPQKPPAGAGTR-VDVGDDELVGSSARKAAGPDPGPGDSPSQRTLGPEAA----QARGRCAAVGTRGRCCWECQQNGWGQPTEQPLPEDLGDPAAACEKPERAAPARDDLGAPGWLREGAAAERSPESVTPVWAPAAVEAAGSPTSPPALPPHPAPSREPLELFTAGFPNHSTQQLQQQQQRTREWVARYPLAPEAGIQGPIRAWSVLPDN-FLQLPSETAFGVSETNSALPEPALSFHSLLPGVPDESSESWPGNPPLTVFRSIR-CQLSLQDLDDFVDQESHGSEESSSGPKESPGTPEEGLQTVLRTSSWGELRDPVEDQFVSPNEGSPCLIPRGLRNRGNVPSFRKAPTVAKSLGDHPQE--TFPAPKFRRSVRRSSRTGRTKSPSSSDEEHLDEDLLKRSRRPPRSRKPSKAGALPSPRVDVVLIQKLANANAVTGQP---HSSWVPGRDGSAALIPHRPSEHRSPLVPLDAREHEWIVRLASGSWFHVQMLFWEDPQLALYRDFLTGYTALHWIAKHGDLNALQDLVSGARKAGVALDVN----VRSSCGYTPLHLAAMHGHQGVIKLLVQRLASRVNIRDCSGKKPWQYLNSNVSGETWQLLGAPRGKPIFPVYSLVQSSSPARKVKSREVSRTVTRKTSLAALLKTQHNKWKLASQYEKFHTPKDREEYSD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZW2-1", "uniprot_id": "SWAHB_MOUSE", "id": "Q8BZW2-1", "name": "Ankyrin repeat domain-containing protein SOWAHB", "aln": "--MAGELSQEALLDFLCQAGGRVRNAELLSHFKSFLRDPHVSPGQLQERRERFKGFVNSVAAVRQDPDGTKYVVLKRRYRDLLGEEGLQRP------GPVDG-----KPRGHRRRDP------------EPQKPPAGAGTQ-VDVG------GSAQKVAGPDPSPEDSPNQRTPEPEAA----QARGRCAAVGTRGRCCWECQQNGWGQSTGQPLPEDLGDPAVACEKPERAAPARDDLGAPGWLREGEAAEHAPGSVPPVWPPTAVEAAGSPTSPPALPPHPAPSREPLELFTAGSPNHSTQQLQQQHQRTQEWVARYLQVPEPEIQAPTRAWSVLPDN-FLQLPSETAFGVSETSSALPEPALSFHSLLPVVLDESSESWPGNAPSTVFRSIR-CQLSLQDLNDFVEQESHGSEESSSGPKESPGTPEEGLQPVLRTSSWGELRDPVEDLFLPPND-SPCLIRRDLGYRGNAPSFRKVPTVAKSLGDHPQE--PFPALKFRRSVRRSSRTGRTKSPSSSDEEHPDEDLWKRSRRPPRSRKPSKAGALPSPRVDAVLVQKLADANAVASQP---HSSWIPSRDGSAALIPHRPSEHRSPLVPLDTREHEWIVRLASGSWLHVLTLFWEDPQLALHRDFLTGYTALHWIAKHGDLCALQDLVSGAQKAGIALDVN----VRSSCGYTPLHLAAIHGHQGVIKLLVQRLASRVNIRDCSGKKPWQYLNSNVSGETWQLLGAPRGKPIFPVYSLVQSSSPARKVKSREVSRNVTRKTSLAALLKTQHNKWKLASQYEKIHTSKEREEYSD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NEL2-1", "uniprot_id": "SWAHB_HUMAN", "id": "A6NEL2-1", "name": "Ankyrin repeat domain-containing protein SOWAHB", "aln": "--MARELSQEALLDFLCQAGGRVTNAALLSHFKSFLRDPDASPSQHQHRRELFKGFVNSVAAVRQDPDGTKYVVLKRRYRDLLGEEGLQRPREPPAAAPSAGGAAPCSPRGARRGEPPQQQPRRRRREKEPEEEPAGAAARAADAACNGLPGSDSRRAPGKGGGSKGSPGQRPPVPAAAAAGAQARASCAAAKTQGRCCWECLQNNLAVLPGELG--ALPHSATAEEKPARALPAQDDRGASREREEGALAEPAPVPAVAHSPPATVEAATSRASPPALLPGPAPRGDRPELLTPSSLHYST--LQQQQQRTREWVARHPQVPEARDQGPIRAWSVLPDN-FLQLPLEP--GSTEPNSEPPDPCLSSHSLFPVVPDESWESWAGNPSLTVFRSIR-CQLSLQDLDDFVDQESDGSEESSSGPKDSPGASEEGLQVVLGTPDRGKLRNPAGGLSVSRKEGSPSRSPQGLRNRGDGHISQQVPAGANGLAGHPLKPLPWPVPKLRRSLRRSSLAGRAK-LSSSDEEYLDEGLLKRSRRPPRSRKPSKAGTAPSPRVDAGLSLKLAEVKAVVAERGWRHSLWVPSGEGSAALAPHRTSEHKSSLVPLDAREHEWIVKLASGSWIQVWTLFWEDPQLALHKDFLTGYTALHWIAKHGDLRALQDLVSGAKKAGIVLDVN----VRSSCGYTPLHLAAIHGHQGVIKLLVQRLASRVNVRDSSGKKPWQYLTSNTSGEIWQLLGAPRGKPIFPVYPLVGSSSPTRKAKSKEISRSVTRKTSFAALLKSQHNKWKLANQYEKFHSPREREEYSD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7Z0B0-1", "uniprot_id": "B7Z0B0_DROME", "id": "B7Z0B0-1", "name": "", "aln": "MELPKELSVAEIRNYMLANECKVTNHALVKHFKKFLTHPQSQ----NEARKRFKTYVTLLSTIKNE-NNQKFLILRKKYVNECPTDEVVER----AVAAASGIPEPSSPGGASLNFD------------SPMRQPPPYKPPPMVTSPPAVSIAKEHQENYQECVDEFTAAIKRIEPARLER--RTSVKSEDLDQQEKPEKTSRSNSIDVIDNKENIPRFSFSSEASSASSTSIEKPEMADPTAPAAVGDVAEN---PISVKEATRKFNRMASEEEAKIISPPAKKKPEKQLIEEKDSPEVTLAHPKAKEWIVSMAKANYQELAKMASEYPELVKLQCPATGYTALHWAAKHGNEDVVKLIAGTYKADVNARTNGGYTPLHLATQFGRDNIFELLWNVYKANRDIMDWSGNKPLDYSRQRSSVSASTCSS-EYAKYFFGADVGNSFRTLGFIESSQITGGTLGSALTRGKKRAQNRFATISGGSLGGVGGAVSRSQSMTVSRRPKKQPGQPISGIFKPATEDGDLLPCEMEGQPVPFRGASTRRKESFLRKTFRATAGGSRRPLAKDVFTNPP--EHEIKARKKHAIEKDLGFLRIGSLNVRVKKTTEAFSNFLGVGNGSGVAPTGYGNGGSAVAANRHHPRSHRAPHQRHHHHVGTTRSRHPNQRAAMSTPYATNGGLPSRASVPNSRNIYDGVHKSWGSADNIPHRSEDLMPPPKAVEYISKRNKSSKRSSYASNTTDSPRDSICSSNSSSNLNGGYSSMPTTPNQLRAPKGIAASFAVDSDSDSACGFDSTWSVNCRGSSSSNPSQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *** : ::: :* * *:.***.** .*. :. *: ** :*. ::::::: :. *:::*:::* : : : . .. .* . .* . *. . .. .. :: :. : * :: . : : . .*. : : .: * . . : : ... * ** . .. .: * .. : * . : : . . : : :. . *.: .: : * . * . : * . * : . . . : . . . . . .:*. : : :*: *: ::. . ... *. . *. :. * : .: : ..:* . : *.: .:.. . . .. : :. .. :* * :...: * : * : .:: : *. . : .... *. .. . . * :. .. :: :..** . .. :* :.. .: * * :* : . . . .* *:* : .:* * . : :* . : .. . : .*: *. : .:**.. . . ... : .: : * . :: *: . ... : . :. . .: *: ", "identical_positions": 69, "similar_positions": 247, "identity": "8.53%" }, { "cls_id": "homologset.agr.HGNC:3296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU13-1", "uniprot_id": "D3ZU13_RAT", "id": "D3ZU13-1", "name": "", "aln": "-------------MNKAPQPTG-----PPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGG--------------FRSLQHFYPSRAQPPSSAASRVQSAAPARP-------------GPAPHVYPAGSQVMMIP-SQISYSASQG--AYYIPGQGRST-------------------------------------------------YVVPTQQYPVQPGAPGFYPG--------------------------------------ASPTEFGTY-------------------------------------AGAYYPAQSVQQFPASVAPAPVLMN--------QPPQIAPK------------------RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGG---SLEPQPNGE-SPQVAVIIRPDDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSES-------------------NLGVLSIPGDTMTTGMIPISVEESTPIS------CESGEPYCLSPEPT-LAEPILEVEVTLSKPIPESEFSSSPLQVSTSLVPHRAETHEPNGVIPSEDLEPEVESSTEPAPPPLSACASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVPS-AALASIVSPTPPVAP-SDTSAAQEEEIEEDED-------EDGEAES------------EKGGED-LPLDSTPVPAQLSQNLEVAAAPQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEVDPAVPEVENQPPTGSN------PSPESEGSAALPQPEEAEETWDSKEDKIHNA----ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHITDVVLDKANKTPLRSLDPSRLPGINCGPDFTPSFANLGRPTLSSRGPPRGGPGGELPRGPQAGLGPRRSQQGPRKETRKIISSVIMTEDIKLNKAEKAWKPSSKRTAADKDRGEED-ADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLA-----IDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTE-----KPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQK----EMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFAKAKP---------RMDQYFNQMEKIIK------------EKKTSSRIRFMLQDVLDLRQSN-WVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMA--KGGDKRRGGP-----------------PGPPVNRG-LPLVDDGGWNTVP--------ISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGR---LSWGKGSSGGS---GAKPSDTASEATRPAT--LNRFSALQQTLPVENTD---------NRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER-SRERPSQPEGLRKAASLTEDR--GRDPVKR---------EATLPPVSPPKAALAVDEVERKSKA-----IIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREH---MGRLLHQLLCAGHLSTAQYYQGLYETLELAEDMEIDIPHVWLYLAELITPILQEDGVPMGELFREITKPLRPMGKATSLLLEILGLLCKSMGPKKVGMLWREAGLSWREFLAEGQDVGSFVAEKKVEYTLGEES----EAPGQRALAFEELRRQLEKLLKDGGSNQRVFDWIEANLNEQQIASNTLVRALMTTVCYSAIIFET-PLRVDVQVLKVRAR-LLQKYLS-DEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWLREAEDEESDHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZJ6-1", "uniprot_id": "IF4G1_MOUSE", "id": "Q6NZJ6-1", "name": "Eukaryotic translation initiation factor 4 gamma 1", "aln": "-------------MNKAPQPTG-----PPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGG--------------FRSLQHFYPSRAQPPSSAASRVQSAAPARP-------------GPAPHVYPAGSQVMMIP-SQISYSASQG--AYYIPGQGRST-------------------------------------------------YVVPTQQYPVQPGAPGFYPG--------------------------------------ASPTEFGTY-------------------------------------AGAYYPAQGVQQFPASVAPAPVLMN--------QPPQIAPK------------------RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGG---SLEPQPNGE-SPQVAVIIRPDDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSES-------------------NLGVLSIPGDTMTTGMIPMSVEESTPIS------CETGEPYCLSPEPT-LAEPILEVEVTLSKPIPESEFSSSPLQVSTALVPHKVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKKVSS-AALASILSPAPPVAP-SDTSPAQEEEMEEDDDDE-----EGGEAES------------EKGGED-VPLDSTPVPAQLSQNLEVAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEVDPAVPEVENQPPTGSN------PSPESEGSMVPTQPEETEETWDSKEDKIHNA----ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHITDVVLDKANKTPLRQLDPSRLPGINCGPDFTPSFANLGRPALSNRGPPRGGPGGELPRGP-AGLGPRRSQQGPRKETRKIISSVIMTEDIKLNKAEKAWKPSSKRTAADKDRGEED-ADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLA-----IDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTE-----KPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQK----EMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFAKAKP---------RMDQYFNQMEKIIK------------EKKTSSRIRFMLQDVLDLRQSN-WVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMA--KGSDKRRGGP-----------------PGPPINRG-LPLVDDGGWNTVP--------ISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGR---LSWGKGSSGGS---GAKPSDTASEATRPAT--LNRFSALQQTLPAENTD---------NRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER-SRERPSQPEGLRKAASLTEDR--GRDPVKR---------EATLPPVSPPKAALSVDEVEKKSKA-----IIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREH---MGRLLHQLLCAGHLSTAQYYQGLYETLELAEDMEIDIPHVWLYLAELITPILQEDGVPMGELFREITKPLRPMGKATSLLLEILGLLCKSMGPKKVGMLWREAGLSWREFLAEGQDVGSFVAEKKVEYTLGEES----EAPGQRTLAFEELRRQLEKLLKDGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFET-PLRVDVQVLKVRAR-LLQKYLC-DEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWLREAEDEESDHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04637-1", "uniprot_id": "IF4G1_HUMAN", "id": "Q04637-1", "name": "Eukaryotic translation initiation factor 4 gamma 1", "aln": "-------------MNKAPQSTG-----PPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---------------------HFYPSRAQPPSSAASRVQSAAPARP-------------GPAAHVYPAGSQVMMIP-SQISYPASQG--AYYIPGQGRST-------------------------------------------------YVVPTQQYPVQPGAPGFYPG--------------------------------------ASPTEFGTY-------------------------------------AGAYYPAQGVQQFPTGVAPTPVLMN--------QPPQIAPK------------------RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGG---GLEPQANGE-TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP-SESQPSSPSPTPSPSPVLEPGSEP-------------------NLAVLSIPGDTMTT--IQMSVEESTPIS------RETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPP--ACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAP-SATSPAQEEEMEEEEEEEEGEAGEAGEAES------------EKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSN------PGPESEGSGVPPRPEEADETWDSKEDKIHNA----ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGP-AGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEED-ADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLA-----IDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTE-----KPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQK----EMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKP---------RMDQYFNQMEKIIK------------EKKTSSRIRFMLQDVLDLRGSN-WVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMA--KGSDKRRGGP-----------------PGPPISRG-LPLVDDGGWNTVP--------ISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGR---LSWGKGSSGGS---GAKPSDAASEAARPATSTLNRFSALQQAVPTESTD---------NRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER-SRERPSQPEGLRKAASLTEDRDRGRDAVKR---------EAALPPVSPLKAALSEEELEKKSKA-----IIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREH---MGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEES----EAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFET-PLRVDVAVLKARAK-LLQKYLC-DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAE-EESDHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B020-1", "uniprot_id": "A0A8M3B020_DANRE", "id": "A0A8M3B020-1", "name": "", "aln": "-------------MNKPPQPITGPPAVPHPAQSPGLTQAAYPPGQPSSVVFPGPSP-QMNTAPQPRQFAPGP---RALHQQGGFRSLQPYYTNRPNMQGSAP-RVPTSNTTRP-------------VAPTHVYQPTSQVMMIPQQQLQFAANSQGHPIYLHGQFRSP-------------------------------------------------YMPPTQQFPVSSGTAGFYGG--------------------------------------SSPAEYGTYDPSLAGRERRGGGGRGTSRENGRLSLHGAPLTSQRYPAAAYYPAT--QQYQTPVPPTPVMMNPAQQQQAPLPQQAAPQPT-----------GPVKPRERKQIRIRDPNQGGRDITEEIMSGGRTTSTPTPPQTAGTEVGSPVQTNGESVPTFPAEISTDDEVKAMVSPASASTPPPCKTP----EPPAPSSIDS-----KPESEV-------------------RPASPESK--------IPSPPEEDLVVP------SPS-PPPANNPQTS---EPQIADSVDAP-VLPEASAQKEPKEPCAPVEPEEAEEKE---------YEPVAETEVTAASSP--AVVASSAVESSPNVAED--RDGAPVITEMPVPELAADEPKEQPLLN--GLPQDSAEVPDVKPESSANPVAEQVVPQDQQS----CLTAVKASV------------EETEKEKAEEAPTPAPVCLVEETTMQAASPIVL---KKKKKIKDLNKK-DVGDVLDAFKEPEEEKPAPEPEVVQKEP------PAP---------PVEETDETWEEKEDKLDTENIEPEASKPVEQKYQYKEEQWKPINPEEKKRYDREFLLGFQFISASMHKPEGLPHISDVVLDKANKTPLRPLDPRSL--MNCGPDFTPSYANLGRQSSG------GGGRGPSARRPQPGRGKDQISRNP-----KIITSVSLKDNIELNQAENAWTPSVKKQVRSRGEEEEDDAEAAKTQELFRRVRSVLNKLTPQMFQQLMKQVTELA-----IDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMGLKVPTSD-----KPGVTVNFRKLLLNRCQKEFEKDKDDDEIFEQKQK----ELDAATEEEERQRLNDELQDAKDKARKRSLGNIKFIGELFKLKMLTEPIMHDCIVKLLKNHD----EDSLECLCRLLSTIGKDLDFEKAKP---------RMDQYFHQMEKIIK------------EKKTSSRIRFMLQDVLDLRKNN-WVPRRGDQGPKTIDQIHKEAELEEHREQIKVQQQLLSKKDSSQGRGGR-----------------GGPHSSGGRGSQTQDEGWNIVP--------ITTKSRPIDTSRLSKITKPG--DFNNQLLAPGGKGSWGSWGKGSSGGT---GAK-STGEQDQGRPTTSTLNRFSALQQSGPPSSSSSSMDS----DRRVPQRNSSSRDRSDRDRGDRDRFDRFDRRDDRDRGLDRPLQAITKRSFSRESEERRGGDNRGPPDSVRRVSSMTDNRDRGSRDRDRSKETVKPMAAPALPPPAPVKPAMSEEDLDKKSKS-----IIEEYLHINDLKEAVQCVQELNSVSLLFVFVRNGVEATLERSTIAREH---IGLLFQKLVSAKILHPEQYYKGLQEILEIADDMAIDIPHIWLYLAEIITPMLQDGGIPMGQLFREVSKPLLPMGKAAILLVDVLNIFCKGLSHKKAGAMWLEAGLSWKDFLPEDEDVNKFVTEQKMEFTLGEES----EKPSKKELTAEELSKHLDRLLQEKANNQRIYDWVEANLDEQKMSSSQFVRALMMSVCQSAIICEN-PYRVDVEQINQRAK-LLQKYLS-DEQKELQALYALQALMVQMEQPANLLRMFFDALYDEDVIKEEAFYKWESSKDPAEQQGKGVALKSVTAFFTWLREAE-SESDNS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DZ29-1", "uniprot_id": "A8DZ29_DROME", "id": "A8DZ29-1", "name": "", "aln": "MQQAIPTLPTQSDIDKAMQPHSAQNMILPANKKTKKYDQQVPTSKPQSLHQPLQPQHSHPTAQPQFQINKAYNVVSILKASAQIAQQSPHLTNQQHPPIHHPQQTQQHQQSYTNVVNRSLSASEPVRAQSSVICNGSSILTVNSRQLNSGDMNSTAIYNISSYRKLTGSLDGNVCFLNVQDIKQNGNISGSVVSNKSIVGVGSEKSSCTGVSINNQIVLPNAQIGTSMGIAGTTTAGTSYMHEKNIVGVSVNCVNTSKKYDFNNSSLLSNNSYPASTAEYVSTGNNNSGNTRSNPQSGGIFRGPPSTPNAPRGASGGATRHVHVQPMYSQPLHQNMVLQQYTQYNPRQQTFPASHLQYAPAPMPYYQYQYVPTLQQQPPHTRSAVTVNTNVNVGNNLQPVQSGPNGPLPVPGASSSQIQLLTSTVQPGASTVMGVGGPGSTMGQVGVPPMVGVGVMTTSVQPQPVQVQPASRRRHQHRLQIIDPTTKKNILDDFDKTKSNTDNEFSDQVTSTNTPATVLSEGPIRIPQQESVGLNNLTSTSSQGSESRTNAPYIPIETTPISRTDVGPTPIVSAMTDAPSVEILPTPQRGRSKKIPIVSPKNVSESIVAPITDETDDAGSTPISRATEESMPPNQTHPNLLISDSSKHKQAVSNSEISKDAPTGLKEMHVAELESSVASENHPAGILDVNVNKSSQSLDFSADPEIDSIGAISPTSPNAVSPILHEVLDNTELSKKLENSTTERFKDSQSVEKPTHQELSLRNATDETEISAMALQDVNSLDNNQIEKTYPSKPKLNVDVSEDISSRESAIKSTSTKNTGVDVGLQSDSKPETTLNDKQDSTDLKVKVSAKISSIINYNEGQWSPNNPSGKKQYDREQLLQLREVKASRIQP---------EVKNVSILPQPNLMPSFIRNNNNNKRVQSMVGIIGNRSNESAGNYIGKQMSMSGVQSGGGRSSMKG---------MIHVNLSLNQDVKLSENENAWRP----RVLNKSDGDSDAKSALEKDELVRRVRGILNKLTPERFDTLVEEIIKLK-----IDTPDKVDEVIVLVFEKAIDEPNFSVSYARLCQRLAAEVKVIDERMESETKSNSAHFRNALLDKTEQEFTQNVSQSTAKEKKLQPIVDKIKKCTDANEKAELEAFLEEEERKIRRRSGGTVRFIGELFKISMLTGKIIYSCIDTLLNPHS----EDMLECLCKLLTTVGAKFEKTPVNS---------KDPSRCYSLEKSITRMQAIASKTDKDGARVSSRVRFMLQDVIDLRKNK-WQTSR-NEAPKTMGQIEKEAKNEQLSAQYFGTLSSTTPGGSQGGSGKRDDRGNSRYGESRSSSAYGGSHSQRGDNGNLRHQQQNNVGGNVSGGAGHSNGNNDENTWHVQTSKGSRSLAVDSNKLEGLSKLSDQNLETKKMGGLTQFIWISSDTTRLSSAPTPTPSNPFAVLSSLIDKNSNERDRDRSGPRNKGSYNKGSMERDRYDRGMHSRTGSSQGSRENSSSRGGQQGRTLLSSSVQKSTSHSKYTQQAPPTRHTVKAQSSVGSSNVNTGPLYRGSEQQTSATFSQTTRSVAPVAVFIEASETDLKLIKSVVSEIVDLSAASKEVTPGAVSCIKRVPEKLRCSFIYYILTDYLHLANVGKQYRRYLSIAVSQLIQQNYISADHLRLAYNEFTVYANDLIVDIPELWLYILQFAGPLIVKKILTISDLWNNNLKENSPSNVAKKFLKTYLIYCTQEVGPNFARNMWIKFNLKWSDFMPESE-VADFIKFNRLEYVENESKSPVIDHRETPEKHVKNVIDHIEHLLKEGTTADCIIDYSNG---NIMVVDKLFIRGLTETLSNFSIHYKDNSYKLESETFQKFCIPVLQRYIDSNEDHQLECLYTLQLLVHGLEHPRGLLSELIGELYDAFVIQKESLCKWRDSKD--QSAGKGVAVKSLNPFFNSLLNDDAN-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39935-1", "uniprot_id": "IF4F1_YEAST", "id": "P39935-1", "name": "Eukaryotic initiation factor 4F subunit p150", "aln": "-------------------------------MTDETAHPTQSASKQESAALKQTGDDQQESQQQRGYTN---------------------YNNGSNYTQKKPYNSNRPHQQRG-------------------------------GKFGPNRYNNRGNYNGGGSFRGG----------------------------------------------------HMGANSSNVPWTGYYNN-----------------------------------------------------------------------------------YPVYYQPQQMAAAGSAPANPIPVEEK-----------------------------------SPVPTKIEITTKSGEHLDLKEQHKAKLQSQERSTVSPQ-------------------PESKLKETSDSTSTSTPTPTPSTNDSKASSEENISEAEKTRRNFIEQVKLR------------------------------------KAALEKKRKEQ---------LEGSSGNNNIPMKTTPENVEEKGSDKPEVTEKTKPAEEKSAEP--------------------EVKQETPAEEGEQGEKGQIKEESTPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSAIESAPVPPSEQVKEETEVAETEQSNIDESATTP-------------------------------AIPTKSDEAEAEVEAEAGDAGTKIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIE-------GPDIKYKKEHVKYTYGPTFLLQFKDKLNVK-ADAEWVQSTASKIVIPPGMGRGNRSRDSGRFGNNSSRGHDFRNTS-------------VRNMDDRANSRTSSKRRSKRMNDDRRSNRSYTSRRDRERGSYRNEEKREDDKP-----------------------------KEEVAPLVPSANRWVPKFKSKKTEKKLAPDGKTELLDKDEVERKMKSLLNKLTLEMFDAISSEILAIANISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGT------------PLEPEMMSEEYYAAASAKRRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQ------------TAKISSRIKFKLIDIKELRHDKNWNSDKKDNGPKTIQQIHEEEERQRQLKNNSRSNSRRTNNSSNRHSFRR-----------------DAPPASKDSFITTRTYSQRNSQ-------------------------------------------------------------RAPPPKEEPAAPTSTATNMFSALMGESDDEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ...: . . : . : . . :: . . : . .* * . . : :. : *..: . .. : . . . : : . . . ::. . * . . . .. . . . . .. : : : : : : . . : ::. . : .. :** . : . . . ::..: :* . . * . . : * : * * .: .. . ..::: *:::.:***** : *: : .:: : . : :. ** :* ** .**::* **.:* : . . : *: : . ** :. :. ::. . .: ::*. * ::*** *:::.:** ::..*. *:: *: **.: .**.*:* .:: .. . ::: * : ***::* * *: :** .: * . : ::.***: **.:* : :. : ... .. . . . . *:. * *:.* .. ", "identical_positions": 69, "similar_positions": 205, "identity": "3.5%" }, { "cls_id": "homologset.agr.HGNC:32960", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC89-1", "uniprot_id": "B1WC89_RAT", "id": "B1WC89-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MAQALEDRNPLSEASDEPCESNAPSTPQIRSHSKDYGSLG--------------RYKGQAVADSANLSRERIIPR---------------ALTVSGANGTRRRGALRELLGLQGAAPTGWLSEEH--------------LEFAASGSRRSSGQGSGRVCLE-----------PREHAWILAAAECRFEVLLEMLEVEPRLLMREDPITGYSVLHWLAKHGRHEELILLHDFARRQGLPFDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADPSRRDYNGNRPCHYLR--------------------PDASLSLRELSGAEEWEIERDRELENANNNSS---SSTTTTTGWLKCTSSVSRIKSVGINYKEASQSVKEKKAW-------------------------GNQGGQGNGLLRQLFPFTQNR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BY98-1", "uniprot_id": "SWAHD_MOUSE", "id": "Q8BY98-1", "name": "Ankyrin repeat domain-containing protein SOWAHD", "aln": "----------------------------------------------------------------------------------------------------------MAQALEDGNPLPKASNRPAESEAPSDPQI----KDNHCLG--------------RYKVQAVRDSANLSQERIFHS---------------ALTVSGASWARRRGELRELLGLQGAAPAGWLSEEH--------------LEPAVPGSRRSSGQGSSRVCLE-----------PREHAWILAAAECRFEVLLEMLEAEPSLLMREDPITGYSVLHWLAKHGRHEELILLHDFARRRGLPFDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADPSRRDHSGNRPCHYLR--------------------PDASLNLRELSGAEEWEIERDRKRENANNNSSRTTTTTTTTSRWLKRTPSASCIKSTGVHYKEASQPVKEKKAS-------------------------STQEGQGRCLRRYLFPFTQNR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJG2-1", "uniprot_id": "SWAHD_HUMAN", "id": "A6NJG2-1", "name": "Ankyrin repeat domain-containing protein SOWAHD", "aln": "----------------------------------------------------------------------------------------------------------MAQLGGAANRAPTASLAPTSQSLRCAPQPRPSRADTGSLG--------------RYWGKAAAAAS---REHPFPG---------------TLMHSAAGSGRRRGALRELLGLQRAAPAGWLSEER--------------AEELGG----PSGPGSSRLCLE-----------PREHAWILAAAEGRYEVLRELLEAEPELLLRGDPITGYSVLHWLAKHGRHEELILVHDFALRRGLRLDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADATRRDHSGHRACHYLR--------------------PDAPWRLRELSGAEEWEMESGSGCTNLNNNSS-------GTTAWR--AASAVGATAVETSRRVAASRTKAKDTA-------------------------GSRVAQMHSLFRHLFPSFQDR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QL15-1", "uniprot_id": "A0A8M9QL15_DANRE", "id": "A0A8M9QL15-1", "name": "", "aln": "------------------------------------------------------------------------MYEGNCNGAISSNEGHFNAP-------PGAEALPSEEPREETNASGNNANSSDSPKNRIASQFRAHLEERLSRHGP------------RSVSPASSAASSSRRSKLHKPPEGWEPGASRKLSVDASEKGSLTPAMRKKYLKELFLNNGSGLSSILLSKHK-----------SSEEEESAEYGDTLNCGYELWALD-----------PMEHAWMLSAVDGNYDTMLEFLAEDPSLLSRKDFISGFTALHWLAKNGRDETLLQLLRHAEKEGLSVNVNLRGSGGMTALHVAAMHEQYMVVKVLVGAFSANIDVMDYNGKRAWQYLK--------------------EKAPREMKELLG--AWDDEHTVGHLNVNNSAS----------------------QAQPVEEHAQDNKAEVDGSG-------------------------GITRQRFRSFKRLLYSAGLIEKI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0B0-1", "uniprot_id": "B7Z0B0_DROME", "id": "B7Z0B0-1", "name": "", "aln": "MELPKELSVAEIRNYMLANECKVTNHALVKHFKKFLTHPQSQNEARKRFKTYVTLLSTIKNENNQKFLILRKKYVNECPTDEVVERAVAAASGIPEPSSPGGASLNFDSPMRQPPPYKPPPMVTSPPAVSIAKEHQENYQECVDEFTAAIKRIEPARLERRTSVKSEDLDQQEKPEKTSRSNSIDVIDNKENIPRFSFSSEASSASSTSIEKPEMADPTAPAAVGDVAENPISVKEATRKFNRMASEEEAKIISPPAKKKPEKQLIEEKDSPEVTLAHPKAKEWIVSMAKANYQELAKMASEYPELVKLQCPATGYTALHWAAKHGNEDVVKLIAG-----TYKADVNARTNGGYTPLHLATQFGRDNIFELLWNVYKANRDIMDWSGNKPLDYSRQRSSVSASTCSSEYAKYFFGADVGNSFRTLGFIESSQITGGTLGSALTRGKKRAQNRFATISGGSLGGVGGAVSRSQSMTVSRRPKKQPGQPISGIFKPATEDGDLLPCEMEGQPVPFRGASTRRKESFLRKTFRATAGGSRRPLAKDVFTNPPEHEIKARKKHAIEKDLGFLRIGSLNVRVKKTTEAFSNFLGVGNGSGVAPTGYGNGGSAVAANRHHPRSHRAPHQRHHHHVGTTRSRHPNQRAAMSTPYATNGGLPSRASVPNSRNIYDGVHKSWGSADNIPHRSEDLMPPPKAVEYISKRNKSSKRSSYASNTTDSPRDSICSSNSSSNLNGGYSSMPTTPNQLRAPKGIAASFAVDSDSDSACGFDSTWSVNCRGSSSSNPSQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : * : .: : . *: .. . : .: * . :: * : *::: .. .:: : :: * *: :*::.*** **:*..: : : :*. .** *.**:*: : :.::* .. *: * .*::. .* : .. :: * : ... . : . . . : . : * : ", "identical_positions": 28, "similar_positions": 80, "identity": "3.57%" }, { "cls_id": "homologset.agr.HGNC:32961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V124-1", "uniprot_id": "EID3_MOUSE", "id": "Q3V124-1", "name": "EP300-interacting inhibitor of differentiation 3", "aln": "------MSKEKCSLTGGKEKRGELVRSLAWQHLVKQEEE------EAVKKEEKEE-----GEDEEEEGSDSSSDDPNPEPPCMHPDLLELVVDREKCRKIRRQYRQLIYTVQQNREDIVNTASD--TLSEALEEAN------VLFDGVSR-TREAALDAQFLVLASDLGKEKAKQLNTDMNFFNPIAFCDLLLLFVGFNWVEEECKEFSDCDDSIVLSFWGMLHEEATSWMLQAETFHFIFGSFKAERSARKPRLGCHKRACKMEGSGDMPTKLRRLDVHANQETTEKEVERILGLLQTYFQKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIIRDGFARIRLDQDRLPILEPTNVSQVDDE-------SDSYSYCRKQGVISLSLQDWKNIVSTFEISEAMIKN-SY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LFN0-1", "uniprot_id": "A0ABK0LFN0_RAT", "id": "A0ABK0LFN0-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "------MSEEKCSLTGGEEKGEELARSLAWQHLVKQAEEDDDDDEEALKKEEEEEEEEEEDEEEEEEGPDSSSDDLSPEAPCMHPDLLELAVDREKCRSIRRQYRQLIYTVQQNREDIVNTASD--SLTEALEEAN------VLFDGVSR-TREAALDAQFLVLASDLGKEKAKQLNSDMSFFNHVAFCELLLVFVGLNWMEEECEELSECDESIALSFWNMLHKEATAWMLQAETFHFIFGSFKAERSARKPRQEHHKRACKMEGNGDMPTKLRKLDVHANQETTEKEVERILGLLQTYFQKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIIRDGFARIRLDQDRLPILEPTNVNQVDEE-------NDSCSYCRKQGVISLSLQDWKNIVSTFEISEAMIKN-SY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N140-1", "uniprot_id": "EID3_HUMAN", "id": "Q8N140-1", "name": "EP300-interacting inhibitor of differentiation 3", "aln": "------MKMDVSVRAAG------------------------------------------------------CSDDLSSGEADVDPKLLELTADEEKCRSIRRQYRQLMYCVRQNREDIVSSANN--SLTEALEEAN------VLFDGVSR-TREAALDARFLVMASDLGKEKAKQLNSDMNFFNQLAFCDFLFLFVGLNWMEGDPDKLSDCDDSIALSFWKAIEKEATSWMVKAETFHFVFGSFKLERSAPKPRLEHQKKVRKMEENGNMPTKLQKLDLSSYPEATEKNVERILGLLQTYFRKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIVRDGFARIRLDEDRLPILEPMNVNQMGEG-------NDSSCHGRKQGVISLTLQEWKNIVAAFEISEAMITYSSY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKV4-1", "uniprot_id": "Q9VKV4_DROME", "id": "Q9VKV4-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "----------------------------------------------------------------------------------MDSSESQSQMDDQDARILRLQN--LIEKNIEIEQQIENNTIG--ESITAIEEII------QTANDISKGHEDRRTNSTELVLDTELLRRNFEVVGKAIQHNTNVTDRMVATAINDLVFKESEED--WDALCSLAIQFGRPLFTNDSMLPFIDVTPKVVVQKQRAPR----------KTKSQVDEK-----RPEKSDQLERKDEGAASVTHMLKQIRQIYRDGNQEPIPYFKLICNPNNFMDTVQNALQLSFLVKENYISIENGEDGLPLVRVVNSKSVEGN-------APS------QAICSIDVTFCEKMVKHYNLHEPMLKRLPVSEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43124-1", "uniprot_id": "NSE4_YEAST", "id": "P43124-1", "name": "Non-structural maintenance of chromosome element 4", "aln": "MSSTVISRKRRNSTVTEPDSSGETRKQKKSRSDEKSSSSKDGDPQLEFKVLQGYRDLESEMHKGRAQVTRTGDIGVAMDNLNAVDSLFNKVIGIKNNGLFAHDARAMVSISELAQISVRNLKFDDSRSMVNLENIVNSLKRYMLKEHFKLNNIAENRNDLTLAADEQSAADQQEESDGDIDRTPDDNHTDKATSSFKATSMRHSYLQQFSHYNEFSQFNWFRIGALYNTISKNAPITDHLMGPLSIEKK-PRVLTQRRRNNDQVGEKITAEKITQHSLNSTQQETTPEQVKKCFKKLSKKLG--PEGSINLFKFIIDPNSFSRSIENLFYTSFLIKEGKLLMEHDEEGLPTIKIKQSISHTDSRSKEIERQRRRAAHQNHIIFQMDMPTWRKLIKKYNITSPFLD-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :. : : :: . .: . . :*: : .. : *. : : : . :. . . . .: : . . :. : : :: . .: : .* : : : : .: *::: :**.* :::* : **::::. :. .:: ** :. : . : : .: : .::: ::: ..:: ", "identical_positions": 12, "similar_positions": 91, "identity": "2.91%" }, { "cls_id": "homologset.agr.HGNC:32962", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6X9-1", "uniprot_id": "F1M6X9_RAT", "id": "F1M6X9-1", "name": "Palmitoyltransferase", "aln": "--------------------------------------------------------------------MKEMSTCGIGQNRVLP-EAQENNVKKLLPRPLSRVNGWSPPLHSFQAISWTTYLAMSIVTFGIFIPFLPTSWKYAANAVMGGVFMFHLVVHLIAITIDPADTNVRLKKDYLEPVPTFDRSKHAHVIQNQYCHLCEVTVS-KKAKHCSSCNKCVSGFDHHCKWLNNCVGKRNYWFFFFSVASAAFGLLGVLIILLYIFIQYFVNPNGLR-----------------------------------------------------MDPLYKGAAVWIGAGWTCLSVFIEISSENTWLLFLSLSPVPVKTPVVLSIAAMVLLLAIASFVLLGHLLVFHFYLISKKLSTFDYMMQTRFQKSP---------------------RPAEKKE-------------------------LPPRKKGNVSQ------------EKSNNLTWPTSPT-----RPRVEPQRLLLSTLSPQSNECFMAPAPKTPPQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14AK4-1", "uniprot_id": "ZDH11_MOUSE", "id": "Q14AK4-1", "name": "Palmitoyltransferase ZDHHC11", "aln": "--------------------------------------------------------------------MKEMNICGINKNWVLP-EAQENNVKKFLPRPLSRVNGWSPPLHSFQAISWITYLAMSIVTFGIFIPFLPYSWKYAANIVMGGVFIFHLIVHLIAITIDPADTNVRLKKDYTQPVPAFDRSKHTHVIQNQYCHLCEVTAS-KKAKHCSACNKCVSGFDHHCKWLNNCVGRRNYWFFFWSVASAAVGILGVMIILCYICIQYFVNPDELR-----------------------------------------------------TDPLYK-----------------EIISENTWLLFLSLWPVPVKTPIVLSIAVMALLLAIASFVMLGHLLIFHLYLITKNMSTFDYLMKTRFKKNL---------------------HPAEEKE-------------------------LPLQKKGDLPQ------------EKSDNWAWPKSP-------PRVGSQKFPVSTLSPKSSVCFVASPPKICHSED--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7U3-1", "uniprot_id": "ZH11B_HUMAN", "id": "P0C7U3-1", "name": "Probable palmitoyltransferase ZDHHC11B", "aln": "-----------------------------------------------------------------------MDTRSGSQCSVTP-EAIRNNEELVLPPRISRVNGWSLPLHYFRVVTWAVFVGLSLATFRIFIPLLPHSWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVN-KKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPRVLR-----------------------------------------------------TDPRYE-----------------DVKNMNTWLLFLPLFPVQVQTLIVVIIRMLVLLLDLLGLVQLGQLLIFHIYLKAKKMTTFEYLINTRKEESSK--------------------HQAVRKDP------------------------YVQMDKGFLQQGAGALGSSAQGVKAKSSLLIYKCPCHFCTSVNQDGDSKAQEADDAPSTSTLGLQQETTEPMKTDSAESED--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZI4-1", "uniprot_id": "ZDH11_DANRE", "id": "E7EZI4-1", "name": "Palmitoyltransferase ZDHHC11", "aln": "--------------------------------------------------------------------MTNLNCFGRHRRRTAPHNATGSRSELVAPPIHSRINGWSSPLHSFQFIALLIFSFMAIVAFGIYVPLLPAPWSYAAYALIGSAFVLHLFSHVTAVTIDPADVNVRRRKDYSSPMPTFDNSKHPHVIDNLHCTLCEVDVS-PKAKHCSTCNKCIADFDHHCKWLNNCVGGRNYWFFFTAVSSAVIGVILLIPLVLFVFIEHYVNPAVLR-----------------------------------------------------TAPQFQ-----------------TVKGNGTWLVFLPVAPVETSSISLLVVSFITALLSLAALLLLCHLLCFHIYLLSQGISTYEYIVRKRQSPNPKEKQQVPPAL----PSNGATAQSLELQEPPLNCD----------APLSSRSCTFKLEDRGPMPEPICAEMEEASGEHHLSYSSESATQKIAGESVMSLPVVWSLSETERPQASQVEVKPLEGRPVVQDPLGSSIMDTALVHQQLMTEQPQYLHFKQKMP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPM2-1", "uniprot_id": "Q9VPM2_DROME", "id": "Q9VPM2-1", "name": "Palmitoyltransferase DHHC domain-containing protein", "aln": "MSTTAAGLKSGPKGAYGVRSETDHIITISTAGLTESHSESPAKGVVTPVRKPHSLGSEDSPENIIPGEQAETNKKPLHLCRLSQLVSYQSNIADVQHRKGRRLHGLQLPLHPLQIFGWLVLLLFGVASYWVLIPAFHARIQGPLYGLITGLYLVHIASHLTALLTDPADKELRRVHRNDRIVPEFDRSKHSHVIENGRCHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVAFLMCVVSAVVATLVIVAAVVAQIVFYYIQPDWLSFYWCPTESSHTIESGDFINITLSLSNGTMMLIEQHTSEEDVHQEMWDEEQANMTISTLPTLLENFTAIIEASATRPGISPTNHTETQPVVTGIGLNETIFMFLLGVLGLLAAVSAGLLLHLCFFHIYISFLGLTTYEYIRNHRQAQDAKTKQLLEGAPGVRAPKNGNVHFSASLPEPHNPSKSLPGGQQLYCCSSAPHPSQHSQESVGQTEQSLRLHCCASSREFHQSGQAIYVCSLLEEAVPQIQVEPDTLSSFHCCSSFAASSLQRRVSLAKGSLISAEPRHLRPATYLQYTEQCTLCTFRLRRGSGPGTGSSGAVSSAGGSSSTRTLTSQTGGSSASATAAGNISKHQRWRRKWNCCAAVPDSPDLPNDLLAALTFRESEEAAAAAKLNAQELPIQFIRTLNGGLDQELPLKATTATPTPPRSSRLRYMLRLLGRYRRPRCRHGAHHGIAAKEHQNIGGSAIKQNQIRPLQLQAAGRGYANSTATPTPPASSPSRSSLESSDLSTSTSPSCGKKELMLLPTSVIRDDSVTTYTLTLPPALPPPTRRKMNQTTQELAELAETLGFASNLQHSQHNSQTNSRTLPSFGNVYRRQRRKHFLRTRSPTLSPIHESGLSNPTSPQPLRHHHQNLANSNSNPAKAMSSPMLNRNSGSANSSALLVQNLCSLAGETLRNSASNSSLQSLSSNSSST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. . *::* . *** :: . :.:.:: : :* : . : . : .*: *: * **** ::* : :* **.***.***:* * **:: .. ::*** ****:. *******:*:*:* *** *: * **. . : :: : : : ::* * . : . : : . .: : : ** . * :* **:*: ::*::*: . * . : . * : . .: ", "identical_positions": 64, "similar_positions": 83, "identity": "6.61%" }, { "cls_id": "homologset.agr.HGNC:3297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62448-1", "uniprot_id": "IF4G2_MOUSE", "id": "Q62448-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MESAIAEGGASRFSASSGGG--GSR---GAPQHYPKTAG---------------------------------NSEFLGKTPGQNAQKWIPARSTRR---------------------------------------------------------------------------------------DDNSAANNSANEK-------------------------------------------------------------------------------------------------------------------------------------------------------ERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQG-RSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQ-----SQFGEMGGKFMKS-QGLSQLYHNQSQGLLSQLQGQ-----------------SKDMPPRFS----KKGQLNADEISLRPAQSFLMN--KNQVPKLQPQI-TMIPPSAQPPRTQTPPLGQT-----PQLGLKTNPPLIQEKPAKTS---------------------------------------------------------------------------KKPPPSKEELLKLTEAVVTDYLNSGNAN---------------------------------------------DAVSGVREMRAPKHFLPEMLSKVIILSLDRS-DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIIS---ELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDN--ISPKLHVD-----------KGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDIT---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNC4-1", "uniprot_id": "A0ABZ3NNC4_RAT", "id": "A0ABZ3NNC4-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------VESAIAEGGASRFSASSGGG--GSR---GAPQHYPKTAG---------------------------------NSEFLGKTPGQNAQKWIPARSTRR---------------------------------------------------------------------------------------DDNSAANNSANEK-------------------------------------------------------------------------------------------------------------------------------------------------------ERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQG-RNDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQ-----SQFGEMGGKFMKS-QGLSQLYHNQSQGLLSQLQGQ-----------------SKDMPPRFS----KKGQLNADEISLRPAQSFLMN--KNQVPKLQPQI-TMIPPSAQPPRTQTPPLGQT-----PQLGLKTNPPLIQEKPAKTS---------------------------------------------------------------------------KKPPPSKEELLKLTEAVVTEYLNSGNAN---------------------------------------------DAVSGVREMRAPKHFLPEMLSKVIILSLDRS-DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIIS---ELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDN--ISPKLHVD-----------KGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDIT---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78344-1", "uniprot_id": "IF4G2_HUMAN", "id": "P78344-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MESAIAEGGASRFSASSGGG--GSR---GAPQHYPKTAG---------------------------------NSEFLGKTPGQNAQKWIPARSTRR---------------------------------------------------------------------------------------DDNSAANNSANEK-------------------------------------------------------------------------------------------------------------------------------------------------------ERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQ-----SQFGEMGGKFMKS-QGLSQLYHNQSQGLLSQLQGQ-----------------SKDMPPRFS----KKGQLNADEISLRPAQSFLMN--KNQVPKLQPQI-TMIPPSAQPPRTQTPPLGQT-----PQLGLKTNPPLIQEKPAKTS---------------------------------------------------------------------------KKPPPSKEELLKLTETVVTEYLNSGNAN---------------------------------------------EAVNGVREMRAPKHFLPEMLSKVIILSLDRS-DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIIS---ELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDN--ISPKLHVD-----------KGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDIT---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4J3-1", "uniprot_id": "A0A8M1N4J3_DANRE", "id": "A0A8M1N4J3-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MESVIAEGGASRFSASSGGG--GGR---GASQHYPKTVG---------------------------------NSEYLGKTPGPSVQRWVPSRSTRR---------------------------------------------------------------------------------------DVN-----SSTEK-------------------------------------------------------------------------------------------------------------------------------------------------------EHHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVDSKLVLKGIILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPTPEIQSSQKQSTTFRRLLITKLQDEFENRTKNVDLYDKQDNPLTSEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHEKAKSLMDQYFGRMQSLMNNKDLPARIRFLLQDTVELRENNWVPRKAFIDNGPKTINQIRQDAVKDLGVFIP-PMNQGMRMDFFLEGPFMPNRMKLDRETLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTLGRHRTNPLFN---GHMASQPQ-----SQFDLGMKPFMKSNQGQNQHFHNQNQNHLNQQQAQ-----------------SKDMPPRF-----KKGQMNADEISLRPAQSFLLN--KNQVPKLQPQIPTMIPPSAQPPRTQTPPLGQP-----PQLGLKTNPPLIQEKPQKTT---------------------------------------------------------------------------KKPPPAREELLKMTENIVTEYLNNRNME---------------------------------------------VAVSGVREMKAPKHFLPEMLSKIILCSLERT-DEDREQASTLINTLRTEGFITGEHFMQALLNVLDQCPKIEVDIPLVKSYLAQFAARAVIA---ELVSVAELAHPLENGNHFPLFLLCLQQASKLKDREWLTDLFQQSKVNMQKMLPEIDQNKDRMLEVLEGKGLSFLFPLLKLEKELLKQIKADPSPQTIYKWIKDN--ISPKLHID-----------KGFINILVTSFLQYIFAELGVP-ECDEQLSFPSKEQLDQEKQLLHSFKPVMQKFLHEHTNLQVSALYALQVHCNANAFPKGMLLRYFVHFYDMEIIEEEAFLAWKEDIS---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z968-1", "uniprot_id": "A1Z968_DROME", "id": "A1Z968-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "MPLSTYDAAPLLHSYDDSPQRWSGVTNGHQAGVIIDQFRGGKAIIIEGGTSTGDTKSIGGGSDLRLVITANPSEIERNYEQPTNRGGGGGGGVIGVSCGGQTPPTPSVGKTLLNTSPNLLPITTATDTFNNLKNLVKIDKGSSPSSGSNSLGGNYRKGGSNGSGYKSAGGNGGSPAISGNSEGGRNGSRSSGGPTGHFSTGYSKNSVKIRQHDSEVSPRPRRSYQGDSSSSRYYPKNSDILGQGLGGNSDSYNGSSSSGRYQQQDQQGGSHRGSRSNYHSNSDGSYNRSINSNSVGGGGSGAVGSGSGGSNYRSARNYENGNGSNGTQPRYGSGNGNGNSSNSNSSSGYNGSAASSTNSKSSYGASRGGNDGGVSSGYSSNYRDNYEDSPSHQRYNNTNSLERNGGGGSGAGASGGPRSYGRSDADRYGGTPSSRTPNLRNGSASAQISGSTSNSSNISLNSGSASAAGGGTPHSQQQQERSQAGKASTPPPITGRWIPPSLRPQHGLTQSEKNDAVFRRVRGILNKLTPEKFQELSDELLKLDLNSIAILKGVILLIFDKALDEPKYSSMYAQLCKRLSEEAPSFD-------KEPSNSSTFLRLLIAVCRDKFNNRLKRDENDNRPPPENEADEEERRHLAKQRMLGNVKFIGELNKLDMLSKNVLHQCIMELFDK--KKKRTAGTQEMCEDMECLAQLLKTCGKNLDSEQGKELMNQYFEKLERRSKSSEYPPRIRFMLKDVIELRQNNWVPRKLGTTEGPVPIKQIRSDDDSIIRTPFP-NRNRDMRNNDRDSDSWMN-RFHLNIQP-GGYNDMFSGLSVT--GASP---IVSPFATSNRDRDRDNRQYNNRGDRNRDRDQGGSGGANYGNRYNKHNQNGGGSGGGSSNNRDRDDSRRNNDRDRDRNDGQYGGNQLLGSKELAPRFKRNLITTNQDAVENLQMRPAANSLLFRAASQNQKFPATLPMSTPPNSSGSNNQGSSQGQLSNSHYPMLGTPTSHLINPTRPSSTPSAEYADNRTLLGVQQERGLKATSSSPNFSSGAEKLDLDGQAGRKGSHDGKDQGKNGSVERPSTPAGGIGSAKQQKKDKGPNKEELSKKASQYFKDRFYYDEEEDAEVTEIEIKDIDETKTEEADAAPVEVSEVKEDAAIPVTTPDRFTKLVDGFLELKLPEKALKDVCINLLMEVLDRVNDVFLERAVRLLQTLRKQSNIKPNIVVEIFKQVVNKMNEREALNPRIVSLVASLLAKTICEP--ALLKLSDIANFTDNGQHYPLFLLVLQQLVKVIGKDALEEKFRASKVDLMNSLPEADRNKERLAGILEDRKLSFLYPLLKVQAEMLKQLQSDPNPNNFYKWIKAN--VDNKYYKD-----------PGFIQALMTVVVKYVTKETTLA-DNLDPKEHPEKSVTQKEQQLLENYSQMLQTFLGQNE-LQLMALYALQTFCYNENFPKGMLCRWFKYLYESEIIEEEAFVLWKEEIS---DKYPGKGSALFQVNAWLTWLQEAESEDDED---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39936-1", "uniprot_id": "IF4F2_YEAST", "id": "P39936-1", "name": "Eukaryotic initiation factor 4F subunit p130", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MTDQRGPPPPHPQQANGYKKFPPHDNQYSGANNSQPNNHYNENLYSAREPHN-NKQYQSKNG------------------------------------KYGTNKYNNRNNSQGNAQYYN-----------------------------------------------------------------------------------NRFNNGYRLNNNDYNPAMLPG-------------------------------------------------------------------------------------------------------------------------------------------------MQWPANYYAPQMYYIPQQMVPVASPPYTHQPLNTNPEPPSTPKTTKIEITTKTGERLNLKKFHEEKKASKGEEKNDGVEQKSKSGTPFEKEATPVLPANEAVKDTLTETSNEKSTSEAENTKRLFLEQVRLRKAAMERKKNGLIS--------------ETEKKQETSNHDNTDTTKPNS--VIESEPIKEAPKPTG----------EANEVVIDGKSGASVKTPQH-----VTGSVTKSVTFNEPEN---ESSSQDVDELVKDD------DTTEISDTTGGKTVNKSDDETINSVITTEENT--------VKETEPSTSDIEMPTVSQLLETLGKAQPISDIYEFAYPENVERPD-----IKYKKPSVKYTYGPTFLLQFKDKLKFRPDPAWVEAVSS--------------KIVIPPHIAR------NKPKDSGRFGG------DFRSPSMRGMDHTSSSRVSSKRRSKRMGDDRRSNR--GYTSRKDREK----AAEKAE-----------------------------------------------------------------------------EQAPKEEIAPLVPSANRWIPKSRVKKTEKKLAP-----------------------------------------DGKTELFDKEEVERKMKSLLNKLTLEMFDSISSEILDIAN--QSKWEDDGETLKIVIEQIFHKACDEPHWSSMYAQLCGKVVKDLDPNIKDKENEGKNGPKLVLHYLVARCHEEFEKGWADKLPAGEDGNPLEPEMMSDEYYIAAAAKRRGLGLVRFIGYLYCLNLLTGKMMFECFRRLMKDLNNDPSEETLESVIELLNTVGEQFEHDKFVTPQATLEGSVLLDNLFMLLQHIIDGGTISNRIKFKLIDVKELREIKHWNSAKKDAGPKTIQQIHQEEEQLRQKKNSQRSNSRFNNHNQSNSNRYSSNRRNMQNTQRDSFASTKTGSFRNNQRNARKVEEVSQAP--RANMFDALMNNDGDSD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39935-1", "uniprot_id": "IF4F1_YEAST", "id": "P39935-1", "name": "Eukaryotic initiation factor 4F subunit p150", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MTDETAHPTQSASKQESAALKQTGDDQQESQQQRGYTNYNNGSNYTQKKPYNSNRPHQQRGG------------------------------------KFGPNRYNNRGNYNGGGSFR-----------------------------------------------------------------------------------------GGHMGANSSN-------------------------------------------------------------------------------------------------------------------------------------------------------VPWTGYYNNYPVYYQPQQMAAAGS-----APANPIPVEEKSPVPTKIEITTKSGEHLDLKEQHKAKLQSQ-ERSTVSPQPESKLKETSDSTSTSTPTPTPSTND--SKASSEENISEAEKTRRNFIEQVKLRKAALEKKRKEQLEGSSGNNNIPMKTTPENVEEKGSDKPEVTEKTKPAEEKSAEPEVKQETPAEEGEQGEKGQIKEESTPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSAIESAPVPPSEQVKEETEVAETEQSNIDESATTPAIPTKSDEAEAEVEAEAGDAGTKIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPD-----IKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTAS--------------KIVIPPGMGRG-----NRSRDSGRFGNNSSRGHDFRNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNR--SYTSRRDRERGSYRNEEKRE-----------------------------------------------------------------------------DDKPKEEVAPLVPSANRWVPKFKSKKTEKKLAP-----------------------------------------DGKTELLDKDEVERKMKSLLNKLTLEMFDAISSEILAIAN--ISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGTPLEPEMMSEEYYAAASAKRRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQTAKISSRIKFKLIDIKELRHDKNWNSDKKDNGPKTIQQIHEEEERQRQLKNNSRSNSRRTNNS---SNRHS-FRRDAPPASKDSFITTRTYSQRNSQRAPPPKEEPAAPTSTATNMFSALMGESDDEE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . : . . . * . . . . : :::.. : : * *: :. . .. : * .. :* .* : . . : *: : * . : : . .: . . : * : * . . . : ... .: .: . .. . . :. . :. . : :: . . : . :.* : : :. : . : ... . .: . . : . * :. . . : . : :: : .: :: : :: . * . . :. . : : :. :: . . : .: . : : * : :: . * : .: . . . *: * * ::: .::*:: .*. :.: . :: :. : * ::: *. . : : . . . .: :. . : :. : . * : ..::* : :. . . : : * :. : ", "identical_positions": 25, "similar_positions": 197, "identity": "1.64%" }, { "cls_id": "homologset.agr.HGNC:32971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IFW3-1", "uniprot_id": "K1C39_RAT", "id": "Q6IFW3-1", "name": "Keratin, type I cytoskeletal 39", "aln": "MDTKGSTVTISSSTPPQNCSGNTNVRTNSS-NKSCY------HDVQSTGHALQTPQGQGCRPSPCLYRCPNYLIRTYSFHPCPDDCSRCSDGINSHEKETMQILNERLASYLEKVRMLEGENADLEDKIQEECSKTLPILCPDYLSYYTTIEQLQQKILCTKAENSRLVSQIDNTKLAADDLRAKYEAELSLRQLVEADANGLKQILDALTLSKADLEARVQSLTEELLCLKTNHEEEINSLQCQLGDRINIEVTAAPSVDLNQILQKMRCQYESIVETNRKDVEEWFNTQMEELNQQVVSSSQQQQCCQKDIIELRRTISALEVELQAQHRMRDSQECILAETEARYTALLAQIQSLIHNLEAQVAEIRSALQRQNQEYEVLLDIKSRLECEIATYRSLLESLDGRLPCNPCTTTWEP----SCQARAMECLTPVYTSISLPGIHKPCRASGPPSRILVKICTITKEIKDGKVISSHEHVQPCYITRPAKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IFX4-1", "uniprot_id": "K1C39_MOUSE", "id": "Q6IFX4-1", "name": "Keratin, type I cytoskeletal 39", "aln": "MDTKGSTVTISSSTPPQNCSGNTNFRTNSSSNKSCC------HDGQSTGCALQTPQGQGCGSSPCLYRCPHYLIRTYSFHPCLDDGSRCTEGINTHEKETMQILNERLANYLEKVRMLEGENADLEDKIQEACSKALPILCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLAADDLRANYEAELSLRQLVEADANGLKQILDALTLSKADLEARVQSLTEELLCLKTNHEEEVNSLQCQLGDRINIEVTAAPSVDLNQILQEMRCRYESIMETNRKDVEEWFNTQMEELNQQVVSSSQQQQCCQKDIIELRRTISALEIELQAQHRMRESQECILTETEARYTALLAQIQSLIHNLEAQVADIRSALQRQSQEYEVLLDIKSRLECEIATYRSLLESLDGRLPCNPCATKWEP----SCQARAMECFTPVYTSSSLPGIHKPCRASGPPSRILVKICTITKEIKDGKVISSYEHVQPCYITRATKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6A163-1", "uniprot_id": "K1C39_HUMAN", "id": "Q6A163-1", "name": "Keratin, type I cytoskeletal 39", "aln": "MDTKGCTTTNSPSTPCQNCSRITNVSTISS-NNGCHPGGLTVNNCQPAGHVLRIPWDQGCQPTPRFCRKPIYLMNNFNARFSLDDCSWYGEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVISSYEHVQPCFIIRPAKV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*.* *.*** **** **. * ** *:.* :: *.:* .*: * .*** .:* : * * **:..:. : . ** * :***::*************.**:****** ***:**.**** ..* **:*************:************************:******:****:*******:*********:.***.******:****.*******.**:**:********:*::********.****:**:***:**.*:********:*****:********:**********:******::.:**:*********:******:**********:******.*****:*:**.**:**.****:***:********:******** **: ** * :*. ** **:: *:*. :*. ** * .::: * *.** **********************:******:* *.:**", "identical_positions": 346, "similar_positions": 94, "identity": "70.33%" }, { "cls_id": "homologset.agr.HGNC:32979", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYQ1-1", "uniprot_id": "A0A0G2JYQ1_RAT", "id": "A0A0G2JYQ1-1", "name": "", "aln": "MSLCESLTFVFKRSYSGFGSAAGACKLGGVNHFRFRARNMAEKGAGGGAGGGSDDSYYEDVGDDCVVKAAVEVFEKLKGISCPFLDGLYITEPKTIMELLCRPSKYRLDILEWMCIRVCPSLQDKFSLLKGNAVDMKIQEMVKLGHDLMLCAPDDQDLLMGRECPQKQLQFMDKLLDMMQSLATGCSSSSSLKEHLEGATEKNDALLGELFSS---PNLWAILKPESDPWPLDMQSSLNKQCDDLPKAG----------------PSAQSEGE-KVADLARQLQESATKLQTLRDQCFAQHKAG-----TDTSTVDQKLRLVISDFYQLILAFLQVYDDELGECCQRPVPSLHPSGPIIQAVYQTLASCGQLLKAVMEIADTSAEAMEAARKQEGEPNCWSSNNSGISLAARIDEVTQKYKILTDRFHRGTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKT8-1", "uniprot_id": "HAUS7_MOUSE", "id": "Q8BKT8-1", "name": "HAUS augmin-like complex subunit 7", "aln": "---------------------------------------MAEEGAG----AGSDDSYYKDVGDDCVVKAAVEVFEKLKGVNCPFLDGLYITEPKTIMELLCRPSKYRLDILEWMCIRVCPSLQDKFISLKGNALDLKIQEMLKLGHELMFCAPDDQDLLMGRECPQKQLQFMDKILDMMQSLATGCSSSSSLKEHLEDTTEKNEALLGELFSS---PNLRAILKPESDPWPLDMQSSLNKQSDDLPKAD----------------PSAQSEGE-KVADLARQLQESATKLQTLRDQCFAQHKAG-----TDTSTIDQKLRLVISDFYQLILAFLQVYDDELRECCQRPVPSLHPSGPIIQAVYQTLASCGQLLRAVMEIADTSAEAMKAARKQEGEPNCWSSNNSGISLAARIDEVTQKYKILTDRFHRGTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99871-1", "uniprot_id": "HAUS7_HUMAN", "id": "Q99871-1", "name": "HAUS augmin-like complex subunit 7", "aln": "---------------------------------------MAGQDAG---CGRGGDDYSEDEGDSSVSRAAVEVFGKLKDLNCPFLEGLYITEPKTIQELLCSPSEYRLEILEWMCTRVWPSLQDRFSSLKGVPTEVKIQEMTKLGHELMLCAPDDQELLKGCACAQKQLHFMDQLLDTIRSLTIGCSSCSSLMEHFEDTREKNEALLGELFSS---PHLQMLLNPECDPWPLDMQPLLNKQSDDWQWAS----------------ASAKSEEEEKLAELARQLQESAAKLHALRTEYFAQHEQGAAAGAADISTLDQKLRLVTSDFHQLILAFLQVYDDELGECCQRPGPDLHPCGPIIQATHQNLTSYSQLLQVVMAVADTSAKAVETVKKQQGEQICWGGSSSVMSLATKMNELMEK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7N2-1", "uniprot_id": "A0AB13A7N2_DANRE", "id": "A0AB13A7N2-1", "name": "", "aln": "-----------------------------------------------------------MAGISKEHQLSLRVYNTLQSLGCPLVDGLYLREADSVQELLCTPSFHRTDILKWICASICPSLKEKFSSIKSTPNEESIEELTRFGYEMMLCKANDKDLIKGLAPPLRQLVFLEQLLRVIQADSSLCSGQNSSSG---DEGVKSNDLLEELISQDHLPDLYMLLDPACNPWPAHIREHLIRTHSAHNKINGNHSKFSDFVSRSDQDSRLVSHGEESLTEAMALLKSTQSTLDELHKECEFLQSHS----SGSAVLSPCALKLAISDMSQLMTAFGHIYNTDFKGYCQRSPPTLSSEMTVFQSVHQLLHTCNTELEAVKQLSETSTSLTHTLQQLQTDRRYWSKGEK-HTLPKQLEELKNRYMAFLSLHQS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : ::.*: .*:.:.**:::***: *..:: **** ** :* :**:*:* : ***:::* :*. . : .*:*: ::*:::*:* .:*::*: * . :** *::::* ::: : **. .* . *.: ** **:*. *.* :*.* .:*** .:: * : . . . *. * .::: *:.: :.*. *: : :. . . *:*. **: **: ** ::*: :: ***. * * . .::*:.:* * : . *..* :::**:. .: :: : : *. ... :*. :::*: :: ", "identical_positions": 83, "similar_positions": 135, "identity": "19.21%" }, { "cls_id": "homologset.agr.HGNC:3298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A378-1", "uniprot_id": "A0A8I6A378_RAT", "id": "A0A8I6A378-1", "name": "", "aln": "VKKIRPHRPSPATEKGAASPGEGDRDPPPPAHEDIAVKGSAAAAGTGPGTGAAAAAAAAAVPPPHPAAAAAAAAAAAAAAAVAAAPPHPNIRALQTPAPQQIPRGPVQQPLEDRIFPPTVSAVYSTVTQVARQPGPPTPSPYSAHEINKGHP------NLAATPPGHASSPGLS-----------------------QTPYPSGQNAGPATLVYPQAPQTMNSQPQAR----SP-------------FFQRPQIQPPRAAIPNSSPSLRPGAQTPTA-VYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPP-------QQYPVQPPGPGPFYPGPGPGDFAN--AYGTPFYPSQPVY-QSAPIIVPTQQQPPPAKREKK---TIRIRDPNQGGKDITEEIMSGGG-SRNPTPP---IGRPTSTPTPPQQLPSQAPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQIPETAAGEPSPEPPRTSSPTTLPPLARSSLPSPMSAALSSQQLLT--AEDKCELSSSKD-DAPPVRSPTSCTAAPGPSLTD--DIGLCKKPCGVAPPDGQLVSSPVLIN---EMNGVGEKLPAKENTVDMVRQEVLPLTLELEILEHPQEERKVECTPTPITPSTMPSFSPAPPTPPASPPCTPVVL--SATIARSPAVATVIQRVVDEGESLRTCLSKDAKETQDKAEAESDGQTEETADPQNAHA--GRSPAPVQTATTAPKTWKKTKERTRTPDEVLEAEAEPKAEEELSVDSVLEPEQEKMSQGFQFERDPSTLKRAKAEEENGEEAEPVRNGAESASEGEGGDANSGSTDSSGDGVTFPFKAESWKPADTEGKKQYDREFLLDIQFMPACIQKPEGLPPISDVVLDKINQPRLPMRTLDPRILPRGP--DFTPAFADFGRQTPGGRGVPLLSVGPRRSQPGQRREPRKIIT-VSVKEDVHLRKAENAWKP--SQKRDSHADDPESIKTQELFRKVRSILNKLTPQMFNQLMKQVSALT-----VDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMAD-----KPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQK----ELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLCN-WVSRRADQGPKTIEQIHKEAKIEEQEEQRKV-QQLMTKE-----KRRPG---VQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVP-----KAQLGSWGKGSSG--------------GAKASETDALRSSASSLNRFSPLQPPAP-SGSPSATPLD--FDSRRALTSRGSMGREKSDK-PLPAGTARPNTFLRG-SSKDLLDNQSQEEQRREMLET---------VKQLTGGVDAERASTEADRSKARELVKSEVCTVPAPDKPALSEEEVERKSKSIIDEFLHIN-----------DFKEATQCIEELSAQGPLHVFVKVGVEFTLERS-----------------------QITRDHMGHLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIVEFSKPLLPVGRAGVLLSEILHLLCRQMSHKKVSALWREADLSWKDFLPEGEDVHNFLLEQKLDFTESEGPCSSEALSKKELSAEELSQRLEKLIMEDKADDERIFDWVEANLDESQMSSPTFLRALMTAVCKAAIVADCSTFRVDTAVIKQR-VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XI3-1", "uniprot_id": "IF4G3_MOUSE", "id": "Q80XI3-1", "name": "Eukaryotic translation initiation factor 4 gamma 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSQPQAR----SP-------------FFQRPQIQPPRAAIPNSSPSIRPGVQTPTA-VYQANQHIMMVNHLPMPYPVTQGHQYCIPQYRHSGPPYVGPP-------QQYPVQPPGPGPFYPGPGPGDFAN--AYGTPFYPSQPVY-QSAPIIVPTQQQPPPAKREKK---TIRIRDPNQGGKDITEEIMSGGG-SRNPTPP---IGRPASTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPETAAGEPTPEPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFT--AEDKCELPSSKEEDAPPVPSPTSCTAASGPSLTD--NSDICKKPCSVAPHDSQLISSTILIN---EMNGVGEKLSAKENTVGMLRQEVLPLTLELEILEHPQEELKVECTPTPIAPSMLPAFSPAPPTPPTSPPCPPVVL--SAAIARSPAVATEVQRVADEGESLRTCLSKDAKEMQDKAESESDGQAEETADPQSLHS--GRSPAPVQTATTAPKSWKKTKEQTRTPDEVLEAEAEPKAEEELAVDSVLEPEQEKMSQGFPSERDPSALKRGKAEEGNGEEAEPVRNGAESASEGEGGDGNSGSADSSADGLTFPFKAESWKPADTEGKKQYDREFLLDIQFMPACIQKPEGLPPISDVVLDKINQPRLSMRTLDPRILPRGP--DFTPAFADFPRQTPGGRGVPLLNVGPRRSQPGQRREPRKIIT-VSVKEDVHLRKAENAWKP--SQKRDSHADDPESIKTQELFRKVRSILNKLTPQMFNQLMKQVSALT-----VDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMAD-----KPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQK----ELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLCN-WVSRRADQGPKTIEQIHKEAKIEEQEEQRKV-QQLMTKE-----KRRPG---VQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVP-----KAQLGSWGKGSSG--------------GAKASESDALRSSASSLNRFSPLQPPAP-SGSPSATPLE--FDSRRALTSRGSMGREKSDK-PIPAGTARPNTFLRG-SSKDLLDNQSQEEQRREMLET---------VKQLTGGLDAERASTEADRSKTRELAKSEMCAVPAPDKPALSEEEVERKSKSIIDEFLHIN-----------DFKEATQCIEELSAQGPLHVFVKVGVEFTLERS-----------------------QITRDHMGHLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIVEFSKPLLPVGRAGVLLSEILHLLCRQMSHKKVGALWREADLSWKDFLPEGEDVHHFLLEQKLDFTESEGPCSSEALSKKELSAEELSQRLEKLIMEEKADDERIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADCSTFRVDTAVIKQR-VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQAGKGVALKSVTAFFTWLREAEEESEDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43432-1", "uniprot_id": "IF4G3_HUMAN", "id": "O43432-1", "name": "Eukaryotic translation initiation factor 4 gamma 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSQPQTR----SP-------------FFQRPQIQPPRATIPNSSPSIRPGAQTPTA-VYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPP-------QQYPVQPPGPGPFYPGPGPGDFPN--AYGTPFYPSQPVY-QSAPIIVPTQQQPPPAKREKK---TIRIRDPNQGGKDITEEIMSGGG-SRNPTPP---IGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPRE-DTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLIN---EINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNS--RRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPRGP--DFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIIT-VSVKEDVHLKKAENAWKP--SQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLT-----VDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMAD-----KPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQK----ELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLCN-WVSRRADQGPKTIEQIHKEAKIEEQEEQRKV-QQLMTKE-----KRRPG---VQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVP-----KAQLGSWGKGSSG--------------GAKASETDALRSSASSLNRFSALQPPAP-SGSTPSTPVE--FDSRRTLTSRGSMGREKNDK-PLPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLET---------VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHIN-----------DFKEAMQCVEELNAQGLLHVFVRVGVESTLERS-----------------------QITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQR-VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IL91-1", "uniprot_id": "A0AC58IL91_DANRE", "id": "A0AC58IL91-1", "name": "", "aln": "---------------------------------------------MSLPPKAVPKPAAAAAAGTGPGTGQLSASQLRTTLTTVPLQSVAQQVFLN--FPSRYPRVPPPLDERIFSTQP-VSAVYS----VQRPPGPP----FTAHEINKGHP------NLAATPPGHASSPGLSQVSVSTVSTAHLYGHPKGWEPGGGSPYTTGQNAGTTPLVYSPTTQPMNAQPQSRPFAPGPRPTHHQGGFRSIQFFQRTQMQTARPTIPSNTPPIRPTSQTPTAAVYSPNQHIMMT-MAHMPFHSPQTAQYYIPQYRHSAPQYVGPP-------QQYPVQPTGPSTFYAAASPGEFPAPYAAGPPYYPGQPVYTPSPPIIVPTPQQPPPAKREKK---TIRIRDPNQGGKDVTDEILSGVGLSRNPTPP---VGRPSSTPTPPQFLCPHPHYPHIFYLKSQ------QLNSQVADHGHIMYNVDSSPHLPASFN----LKADDKPKLEFSLQRTASPGLRQPDTPLERRDPSSPVQTPSSPPHKPELPPSD----SETASSVATAPTPSI-PASTEESADAPSPLAEPSLTKAITPEPESSEPEKSSSPPPQSLSGSLTQHEKAVNGLTD-VDAAPLSEELETQP--REASPLLPTSSVPQSEPRPVTPVLEEESDPINMNSPLPPVEDDAGCPDNVSPSLSTSTTAAISTTPPAPPPGLSHPSQVSAALDRRPSNGAEIKETGK-ENEALPDKRGEPFLQSRKSSNQATSSAPKTWKKPKEDMPVGQDQCPDKEEDT-------DQASMEPAPESPSPPPVEVERRPSVGAVLEENGEQEVEPLRNGAEHTSETESSDSI-----HPP-AVKEPLIKVLPQPAEKNGKKQYNRDFLLGFQFMPACVQKPEGLPPISDVVLDKINQNKLPMRPVDPRVLSRGP--DFTPAFADFSRPISGGRGAPLLNVGMRRPPG------RKIITNVSVIDEVQLKTTENAWKP--GMKREGAVEDPDAQRTQELFRKVRSILNKLTPQMFSQLMKQVTDLT-----IDTEERLKGVIDLVFEKAINEPSFSVAYGNMCSCLATLKVPMTD-----KPNSTVNFRKLLLNRCQKEFEKDKMDDDAFEKKHR----ELEAATASSERERLQEELEEAKDKARRRSIGNIKFIGELFKLRMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLHN-WVSRRADQGPKTIEQIHKDAKLEEQEEQRKVHQQLLSKDN----KRRP-----VVQREETWSTVPMTKNSRTIDPAKIPKFSKPAIDEKIQLGP-----RAQVN-WMKGSSGGA------------GAKASESDASRPS-ASLNRYSPLQPSALQTSSLPSTSPD--FDSRRVLGSRGSSGRERNDK-PLSAGPARTGPISLSSSNKETPEELVQEVSRRDSNAS---------DTPKLLVSTAD-KSRLENSQPRESAVKLEALSGPSPDKPALSEEEMERRSKSIIDEFLHIN-----------DYKEALQCVEELEQSAMLYVFVRVGVESTLERS-----------------------QITRDHMGQLLFQLLQAGVLPKLQFFKGFSETLELADDMAIDIPHIWLYLAELVTPVLREGGISMRELFSEFSKPLLPVGRAGILFSEILHLLCKQMSHKKVGSLWRDSGLSWADFIPETEDVHSFITEHKLEFTLSDGSNPTEAVSKRTLSPEELNKQLEKLLLEDMVGDEQIFDWVEANLDESEMSSAPFVRALMTAVCKAAVKTEGSSCKVDLSIIQTR-LPVLHKYLNSDTERQLQALYALQALIVKLDQPANLLRMFFDCLYDEDVISEDAFYKWEVSKDPAEQQGKGVALKSVTAFFTWLREAEEESEDN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BDQ6-1", "uniprot_id": "A0A8M3BDQ6_DANRE", "id": "A0A8M3BDQ6-1", "name": "", "aln": "---------------------------------------------MSLPPKVVPKPAAVAVS--GHVTGPAPPTQLRAALTSVSLPPGAQNAPPSAVPPTQIPRAALSLDERMFPAHSGVTAVYS----VSRHPGPP----FPGHDLSKTHP------NLAGTPPGHATSPALSQVSVP---AGPSYRILKPWETGGAPPYNPAQNAGSAPLVYSPQTQPMNVQPQTRPFVTGPRPTHHQ-------FIHRSQMQPARPTLPTNNPSIRPGSQTPTATVYPPNQPIMMT-MTPMPFAT-QTHQYYIPQYRHSAP-YVGPP-------QQYAVQPPGSGTFYPGPSPAEYPTPYAAGPPYYTGQTVYPPSPPIIVPAPMPPPPTKREKKPSSQIRIRDPNQGGKDITEEIMFGS---RNPTPP---AGHPASTLTPPAGRPSSTPTPPSGRLSSTPTPPQRPSNCQTPEQTAYVNQTQRLSESPAPMDGKPSLAIDDRPKMESGPIKSISPGPRPSESCLEKREISSLPLLVSSSPE----------------VDVSSHPTS----GCIKPTAAGEPEFISPSATKAQTYQVISGEESVPEASPRLSASLSLR----VVNGVNE-PQTPSSYEEPEVQEALKMSSSCEIQGTSFMEESGQEVPVALEELQ----AEHLPSLAAHVPLIPGVQASSITSSTTSVLAPPPGLAP-LVQSVVLEVSEQNKTSDDVQLKAQDASESQTQSNSR-------KFTPAQAVPVVPKPWKKPNDEDLMMETLKKENEEETSKDCSAGDEMVLQSSLGTYSSPFTVPEHQEKHS---EENGETETEPFRNGVETESTDSGVTLG-----DSRGSMCSPTQLIQEGLVQSNGKRQYDRDFLLGFQFMPACVQKPEGLPPISDVVLDKMNQNKLPLRSVDPRLISRGTPQDFTPAFADFSRQMAGGRGAPLLNV--RRLPP------RKIIVNLSVSDDVQLKKAENAWKP--GMKREGVAEDPETIRTQELFRKVRSILNKLTPQMFHQLMKQVTDLT-----INTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLATLKVPTAD-----KPNTTVNFRKLLLNRCQKEFERDKVDDVVLERKQK----EIDSATSPTEKERLQEELEEAKDKARRRSTGNIKFIGELFKLKMLTEPIMHDCVVKLLKNHD----DESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLHN-WVSRRADQGPKTIEQIHKEAKLEEQEEQRKVHQQLLSKDM----KRRPDQREQRSMREETWNTVPTTKNSRTIDPTKIPKISKPQIDEKIQLGP-----RAQIN-WVKGSSG--------------GAKASDSELTRSAGNTLNRYSALQSSTSQSSSTPAQTSE--SEPRRSLGSRGSMGRERSEK-PVSLGPSRPGPFGRGSSAKELIDNMVPEETRREGQDS---------HHTSRKASISEEKCEMENSRSAESVKSETLLVSGVSEKPVLSEEEIERKSKAIIDEFLHIN-----------DYKEAVQCVLEIEQPSMLCVFVRMGLESTLERS-----------------------QKAREHMGLLYYQLIQKGILPHSQLYKGFSEMLEQADDMAIDIPFIWLYLAELLSPLLKEGGINMRELFSELSKPLLPVGRAAILFSEILHLLCKQMSHRKVGDLWRESGLNWADFLPEGEHLPAFISQHKLEFTVSDISPVSPASAKPSLSPEELFKQLEQLLLEDMSSDEQIFDWIEANLDESQMSSSPFLRALMTAICKAAVKDESTSCRVDTAIIQKR-LPILHKYFDSDTERQLQALYALQSLIVALDQPPNLLRMFFDCLYDEDVISEDAFYQWETSKDPAEQLGKGVALKSVNAFFTWLREAEEESEDN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DZ29-1", "uniprot_id": "A8DZ29_DROME", "id": "A8DZ29-1", "name": "", "aln": "--------MQQAIPTLPTQSDIDKAMQPHSAQNMILPANKKTKKYDQQVPTSKPQSLHQPLQPQHSHPTAQPQFQINKAYNVVSILKASAQIAQQSPHLTNQQHPPIHHPQQTQQHQQSYTNVVNRSLSASEPVRAQSSVICNGSSILTVNSRQLNSGDMNSTAIYNISSYRKLTGSLDGNVCFLNVQDIKQNGNISGSVVSNKSIVGVGSEKSSCTGVSINNQIVLPNAQIGTSMGIAGTTTAGTSYMHEKNIVGVSVNCVNTSKKYDFNNSSLLSNNSYPASTAEYVSTGNNNSGNTRSNPQSGGIFRGPPSTPNAPRGASGGATRHVHVQPMYSQPLHQNMVLQQYTQYNPRQQTFPASHLQYAPAPMPYYQYQYVPTLQQQPPHTRSAVTVNTNVNVGNNLQPVQSGPNGPLPVPGASSSQIQLLTSTVQPGASTVMGVGGPGSTMGQVGVPPMVGVGVMTTSVQPQPVQVQPASRRRHQHRLQIIDPTTKKNILDDFDKTKSNTDNEFSDQVTSTNTPATVLSEGPIRIPQQESVGLNNLTSTSSQGSESRTNAPYIPIETTPISRTDVGPTPIVSAMTDAPSVEILPTPQRGRSKKIPIVSPKNVSES-IVAPITDETDDAGSTPISRATEESMPPNQTHPNLLISDSSKHKQAVSNSEISKDAPTGLKEMHVAELESSVASENHPAGILDVNVNKSSQSLDFSADPEIDSIGAISPTSPNAVSPILHEVLDNTELSKKLENSTTERFKDSQSVEKPTHQELSLRNATDETEISAMALQDVNSLDNNQ--IEKTYPSKPKLNVDVSEDISSRESAIKSTSTKNTGVDVGLQSDSKPETTLNDKQDSTDLKVKVSAKISSIINYNEGQWSPNNPSGKKQYDREQLLQLREVKASRIQPEVKN-VSILPQPNLMPSFIRNNNNNKRVQSMVG------IIGNRSNESAGNYIGKQMSMSGVQSGGGRSSMKGMIHVNLSLNQDVKLSENENAWRPRVLNKSDGDSDAKSALEKDELVRRVRGILNKLTPERFDTLVEEIIKLK-----IDTPDKVDEVIVLVFEKAIDEPNFSVSYARLCQRLAAEVKVIDERMESETKSNSAHFRNALLDKTEQEFTQNVSQSTAKEKKLQPIVDKIKKCTDANEKAELEAFLEEEERKIRRRSGGTVRFIGELFKISMLTGKIIYSCIDTLLNPHS----EDMLECLCKLLTTVGAKFEKTPVNSKDPSRCYS--LEKSITRMQAIASKTDKDGARVSSRVRFMLQDVIDLRKNK-WQTSRNE-APKTMGQIEKEAKNEQLSAQYFGTLSSTTPGGSQGGSGKRDDRGNSRYGESRSSSAYGGSHSQRGDNGNLRHQQQNNVGGNVSGGAGHSNGNNDENTWHVQTSKGSRSLAVDSNKLEGLSKLSDQNLETKKMGGLTQFIWISSDTTRLSSAPTPTPSNPFAVLSSLIDKNSNERDRDRSGPRNKGSYNKGSMERDRYDRGMHSRTGSSQGSRENSSSRGGQQGRTLLSSSVQKSTSHSKYTQQAPPTRHTVKAQSSVGSSNVNTGPLYRGSEQQTSATFSQTTRSVAPVAVFIEASETDLKLIKSVVSEIVDLSAASKEVTPGAVSCIKRVPEKLRCSFIYYILTDYLHLANVGKQYRRYLSIAVSQLIQQNYISADHLRLAYNEFTVYANDLIVDIPELWLYILQFAGPLIVKKILTISDLWNNNLKENSPSNVAKKFLKTYLIYCTQEVGPNFARNMWIKFNLKWSDFMPESE-VADFIKFNRLEYVENESKSPVIDHRETPEKHVKNVIDHIEHLLKEGTTADCIIDYSNG---NIMVVDKLFIRGLTETLSNFSIHYKDNSYKLESETFQKFCIPVLQRYIDSNEDHQLECLYTLQLLVHGLEHPRGLLSELIGELYDAFVIQKESLCKWRDSKD--QSAGKGVAVKSLNPFFNSLLNDDAN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39935-1", "uniprot_id": "IF4F1_YEAST", "id": "P39935-1", "name": "Eukaryotic initiation factor 4F subunit p150", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDETAHPTQSASKQESAALKQTGDDQQESQQQRGYTNYNNGSNYTQKKPYNSNRPHQQRGGKFGPN------RYNNRGNYNGGGSFRGGHMGANSSN--VPWTGYYNNYPVYYQPQQMAAAGSAPANPIPVEEKSPVPTKIEITTKSGEHLDLK-------------------EQHKAKLQSQERSTVSPQPESKLKETSDSTSTSTPTPTPSTNDSKASSEENISEAEKTRRNFIEQVKLRKAALEKKRKEQLEGSSGNNNIPMKTTPENVEEKG-----------------------------------------------------SDKPEVTEKTKPAEEKSAEPEVKQETPAEE---GEQGEKGQIKEESTPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSAIESAPVPPSEQVKEETEVAETEQSNIDESATTPAIPTKSDEAEAEVEAEAGDAGTKIGLEAEIETTTDETDDG-------------------TNTVSHILNVLKDATPIEDVFSFN-------------------YPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQS-----------TASKIVIPPGMGRGNRSRDSGRFGNNSSRGHDFRNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNRSYTSRRDRER--------GSYRNEEKREDDKPKEEVAPLVPSAN------------RWVPKFKSKKTEKKLAP---------DGKTELLDKDEVERKMKSLLNKLTLEMFDAISSEILAIANISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGT------------PLEPEMMSEEYYAAASAKRRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQTA-----KISSRIKFKLIDIKELRHDKNWNSDKKDNGPKTIQQIHEEEERQRQ------------------------------------------------------------------------------------------------------LKNNSRSNSRRTNNSSNRHSFRRDAPP--------------ASKDSFITTRTYSQRNSQR----APPPKEEPAAPTSTATNMFSALMGESDDEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . : : .* : : .: : . : . * . . : :. : *:.: .: . . : : . :. . : . . .: : . . .*: : . :: . . . * : . .. . .: ..: *: * . .:*: *:::.:***** : * : .:: : . : :. ** :* ** :** :* *..:* :. . . : *: : . ** :. :. :.. . .: . :**. * ::*** *::: :** ::..*. *:: :: **.: .**.*:* .:: .. ::. : :: * . : ***::* * *: :** : * : : : .***: **.:: : :. * .. . .:. . : : : .. . . . . . .: ", "identical_positions": 61, "similar_positions": 177, "identity": "3.11%" }, { "cls_id": "homologset.agr.HGNC:3299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07205-1", "uniprot_id": "IF5_RAT", "id": "Q07205-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDIGTGKKEKE-KKNRKGK---DKENGSVST--------------SETPPPPPP-NEISPP---HAVEEEEDDDWGEDTTEEAQRRRMDEISDHAKGLTLSDDLERTVEERVNILFDFVK-KKKEEGIID--SSDKD-------IVAEAERLDVKAMGPL--VLTEVLFDEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKTAS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AVQ3-1", "uniprot_id": "A0A8I6AVQ3_RAT", "id": "A0A8I6AVQ3-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKVLNRPPTYPTKYFGCELGAQAQFD--NDRYIVNGSHEANKLQDMLDGFIKKF-----CENPETDLHVNPKKQTIGNSCKACGYRGMLDTHQKLCTFILKNPPENSDIGTGKKEKE-KKNRKGK---DKENGSVST--------------SETPPPPPP-NEISPP---HAVEEEEDGDWGEDTTEEAQRRRMDESSDHAKGLTLSDDLERTVEERVNILFDFVK-KKKEEGIID--SSDKD-------IVAEAERLDVKAMGPL--VLTEVLFDEKIREQIKKYRRHFLRFCHNNKKAQWYLLHGLECVVAMHQVQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIHVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKTLS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59325-1", "uniprot_id": "IF5_MOUSE", "id": "P59325-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDIGTGKKEKE-KKNRKGK---DKENGSVST--------------SETPPPPPP-NEISPP---HAVEEEEDDDWGEDTTEEAQRRRMDEISDHAKGLTLSDDLERTVEERVNILFDFVK-KKKEEGIID--SSDKE-------IVAEAERLDVKAMGPL--VLTEVLFDEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKTAS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55010-1", "uniprot_id": "IF5_HUMAN", "id": "P55010-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDSGTGKKEKE-KKNRKGK---DKENGSVSS--------------SETPPPPPPPNEINPPP--HTMEEEEDDDWGEDTTEEAQRRRMDEISDHAKVLTLSDDLERTIEERVNILFDFVK-KKKEEGVID--SSDKE-------IVAEAERLDVKAMGPL--VLTEVLFNEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKAAS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXK6-1", "uniprot_id": "IF5_DROME", "id": "Q9VXK6-1", "name": "Eukaryotic translation initiation factor 5", "aln": "MATVNVNRSVTDIFYRYKMPRLQAKVEGKGNGIKTVLVNMAEVARAIGRPATYPTKYFGCELGAQTLFDHKNERFVVNGSHDVNKLQDLLDGFIRKFVLCPECDNPETNLTVSAKNQTISQSCKACGFHGLLKVNHKVNTFIVKNPPSLNPAAQGSSLTEGKRSRKQKQKNDNADGSMTNNSLANNSGGESDGGNGTNQASQTEAEISAAIPEKTAKDDDDEGWSVDVSKEAIRARLQDLTDGAKGMTISDDYDKTEKERIDIFYELVK-DKRDKKQLDDVQTHKE-------LVIEAERLDIINKAPL--VLAELLFTENIIKDVQKNRPLLLRFTLNNPKAQRYLIGGVEQTVELHKGILMSKVAGIFKLFYDLDILDEAVILEWAQKVSKRHVSKNIAAEIHEKAMPFVLWLKNAEEESSESEEEEDDESEEDNYVSSAGQRGGQRVVQRGIPRAVAGDEDD-EDDVNIDDI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38431-1", "uniprot_id": "IF5_YEAST", "id": "P38431-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSINICRDNHDPFYRYKMPPIQAKVEGRGNGIKTAVLNVADISHALNRPAPYIVKYFGFELGAQTSISVDKDRYLVNGVHEPAKLQDVLDGFINKFVLCGSCKNPETEIIIT-KDNDLVRDCKACGKRTPMDLRHKLSSFILKNPPD-SVSGSKKKKKAATASANVR----GGGLSISDIAQ-----------GKSQNAPSDGTGSSTP----QHHDEDEDELSRQIKAAASTLEDIEVKDDEWAVDMSEEAIRARAKELEVNSELTQLDEYGEWILEQAGEDKENLPSDVELYKKAAELDVLNDPKIGCVLAQCLFDEDIVNEIAEHNAFFTKILVT-PEYEKNFMGGIERFLGLEHKDLIPLLPKILVQLYNNDIISEEEIMRFGTKSSKKFVPKEVSKKVRRAAKPFITWLETAESD----DDEEDDE-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: *. * ******* : *****:******.::*:.::::.:.**..* .**** *****: :. ::*::*** *: ****:*****.** *.****:: :. *.: : ..***** : :. .:*: :**:****. . . .. . . . : : . *:: . : .. ... .:::: . : . * . : .* : :*:: :: :.::: ::.: .: : :: .*: : :* .**: : **:: ** *.* ::: : . : :: . : : :: *:* : :.: *:. :. *: :*: *::.* *: :. * **:.*.*::: ::: * **: **: **.: ::*::** ", "identical_positions": 105, "similar_positions": 158, "identity": "22.11%" }, { "cls_id": "homologset.agr.HGNC:33", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VRG4-1", "uniprot_id": "Q9VRG4_DROME", "id": "Q9VRG4-1", "name": "", "aln": "------------MAKVTNWDKFVLLLWKNWTLQWNHKWQMVIELVLPAIFSLLLVLVRTLVDTEQK-GVRYYNEQNLTDLNLLQHSLHRSSYLGKLIALIAPNRRRKNGGFSKFEFILCYSPVNPVLKKLVEEAWQSLG--KNKICESENATQLELDTVSKNAFAGVQFDDAWANLTENDPLPNDFHFALRFP------AELRTATIAIANTWLTMRLFPTIDLTGPRNEGDDDGGIPPGYLREGFLPLQHSLS---MAYLRQKSGEQD--LPNVVMKRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYITAEKEKQLKEVMKIMGLSNWLHWTAWFVKSFIMLTISAILIAILVKINWS-EDVAVLTHANFTALVFFLIIYIVSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLIS-NTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFWCGEREYTGVED---------------------IPNG--HVEQRDPKAFETEPEGKHIGLQMRHLKKRFGN----KMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTAIINGSDIRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRG-KAVEQEVAKYLKMIELEDKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWDLLQQEKVGRTLLLTTHFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGSG--YRLICVKRDDCETNEVTALLNKYIPGLKPECDIGAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAEKDNTGNIKDQHEIMNGGSGFRGEDDNESVQ---------------------------SDGIFSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNKLLLLIQNIMPVFFVVVTILIIKTQGTFQEL---KPITISLTQYPLAVTVLDRSNVQNGTGYEIANKYEDLARSYGSNYGL----ELTGTQGFEDYILDLGKTIQVRINSRYLVAATITESK----ITAWLNNQALHTAPLTVNMVHNAIADKLFG-------------------------------------------------------------------SSVKIQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSELFDTKDTADILGWIFRIFPHFSLAMSLNKVYTNTATRNACAKAGA--LPPILLCELVPQCCNLKPYFAWEEPGVLPETVYMAVTGVVFFLIIIVLEFRLINELMFKIRQLISKPP----PPPTEGQLDDD-VANERERILQMS--SNELATKNLVLDRVTKYYG---QFMAVNQVSLCVQEVECFGLLGVNGAGKTTTFKMMTGDERISSGAAYVQGLSLESNMNSIYKMIGYCPQFDALLDDLTGREVLRIFCMLRGVQESRIRQLSEDLAKSFGFMKHIDKQTHAYSGGNKRKLSTAIAVIGSPSVIYLDEPTTGMDPAARRQLWNMVCRIRDSGKSIVLTSHSMEECEALCTRLAIMVNGEFKCIGSTQHLKNKFSKGLILKIKVRRNLEALRQARLSGGYARNPD-------------------------------------------EQTVPAQMSQRD-IDAVKEFVETEYPNSILQEEYQG--ILTFYIPLTGVKWSRIFGLMESNRDQLNVEDYSVSQTTLEEIFLEFAKYQREDTRANQ------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVJ9-1", "uniprot_id": "Q9VVJ9_DROME", "id": "Q9VVJ9-1", "name": "ABC transporter domain-containing protein", "aln": "MKSERESFSTSEIYAVGDWDKLKLLMWKNWILQWNQKMQIVFALVLPVLFLCLILVLRIIVLPEKM-DEIRYPTVSISDLNLYMR-----------MVPLGNRILHENGSLNIPRNFLCYTPNNPINSAIVGATAIRLR--LLGTRAYDTALHMEQDMVLHNFLAGVQFEDNENVNTNDAGYPLNLNYSLRFP------SELRTMQGPIIDTWRTSRLFLSYDTSGSRNRLDNDGGVPVGYIREGFLPIQHALT---MSWLALASGVTDTGIPAIHLQRFPYRAYTYDQLLSGLRQLLPFVILLSFIYPASTVTKYVTSEKELQLKEIMKLIGVHNWLHWVAWFVKSYIMLMLVVFLIMSLIMVKFY-ASVAVLTFSSWVPVLLFLHTYVVTSVCLCFMLAVLFSKASTASAVAAIFWFLTYIPYSFGYYYYERLSLMSKLLISLIFSNSALGFGIHVIVMWEGTGEGITWRNMFHPVSTDDSLTLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYWR--QYVPSLNI---------------------VPSF--QTILHGSAKAKSCRRAREVGIQLFNLQKNYGK----LKAVKGISLKMHRNEITVLLGHNGAGKTTTINMITGIVKPTSGTAIVNGYDIRTHLAKARESLGICPQNNILFKEMSVRDHIIFFSKLKGIRGTKAVENEVGKYMTMLKLQDKSYVAAKNLSGGMKRKLSLCCALCGNAKVVLCDEPSSGIDAAGRRSLWDLLQSEKDGRTILLTTHYMDEADVLGDRIAILSEGKLQCQGTSFYLKKRFGTG--YLLVCIMQSGCDVGAVTQLIRKYVPPIKPERVLGTELTYRLPTEYSKKFAELLQDLDEKCAQLQLVGYGLSGATLEDVFMAVNTDKRVQGGAE--------GPPVDGSIDFKELV---------------------------FDSKTREKRRIRR----CFMFWQALFLKKFYTTTRNYWLLGIQLVLPIAVMALTILNSRGGRIYYEL---PAMPISINQYSSAYVVLEDNTTDKTS--SLADAYSKHLEHYARRCTL----LRTGDLKFEDYILSHDVNHSRRIDFHFLAGLTVSENN----FIVWLNNKPLHTAPLTLNLLHNALAIKLLG-------------------------------------------------------------------QDASTYVTNEPLPYSDDTRTLRLNKGQVLGAEISINLSLTMCFITAFYAIPIIRERETRAKLLQFLSGVDVCAYWTSHIVWDYLVFVLSALSSILTIAAFKEIGYITPLDLSRYFYMLLIFGFPGIMLSYAASGCFSDAATGFTRISIINTLMGTGLFLMFMTLNFEAFQLKDVAEKLAWYFRLSPHYSLASSTHSIHIGYNIRRGCSIGGIRKLPKQLRCRNVPICCDIPGYYGWRKPGVLVEITYMIMLGSTLFLLIVMHDAKVCNLIAEKLGNCFSKRK----RVEGGTSIENDSVVAEQRVVREMI--NSGRKDVPLLVYKISKRYR---SKLAVKAISFHVPHAECFGLLGINGAGKTSTFKMLAGDEKITSGEAYIDGTNIST--HKVYRKIGYCPQFDALFEDLTGRETLNIYCLLRGVQRRHVTPICWGLAISFGFAKHMDKQTKHYSGGNRRKLSTAISVLGNPSVLYLDEPTSGMDPAARRQLWQIIGLIRTAGKSIVLTSHSMDECEALCSRLAIMVDGEFKCLGSVQSLKNQFSKGLILKVKVKHKKKTFQRVVEDSSSSNDKKSISETDLKF---------------------------------LQMASVMESSQADRILKVNRFISKEIPDAELKEEYNG--LITYYIPHS-KTLSKIFQLLETNSHKLNIEDYLIMQTRLEEIFLDFASKRDSSDIFTKRIYSCSWPPVS-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0G2K1Q8-1", "uniprot_id": "ABCA3_RAT", "id": "A0A0G2K1Q8-1", "name": "Phospholipid-transporting ATPase ABCA3", "aln": "---------------MVVLRQLRLLLWKNYTLKKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVPNATVYPDQHIQELPLFFSFP------------------PPGGSWELAYVPSHSDAARTITEAVRREFMIKMR-VHGFSSEKDFEDYVRYDNHSSNVLAAVVFEHTFNHSKDPLPLAVRYHLRFSYTRRNYMWTQTGNLFLKETEGWHTASLFPLFPSPGPREPSSPDGGEP-GYIREGFLAVQHAVDKAIMHYHANASAHQLFQKLTVITKRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKLKEYMRMMGLSSWLHWSAWFLMFLLFSLIVVSFMTLLFCVKVK-KDIAVLSNSDPSLVLAFLLCFAISSISFSFMVSTFFSKANMAATVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLSCLLS-NVAMAMGAQLIGKFEAKGTGIQWCDLLNPVNVDDDFCFGQVLGMLLLDSVLYGLVTWYVEAVFPGQFGVPQPWYFFLMPSYWCGNPRTVVGKE---------------------EEGG-DPEKAFRTEYFEAEPEDLAAGIKIKHLSKVFQVGNKDKMGIRDLTLNLYEGQITVLLGHNGAGKTTTMSMLTGLFPPTSGHAYIRGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAEHLYFYAQLKGLSV-QKCPEEVKQMLHTLGLEDKRDSRSKFLSGGMKRKLAIGIALIAGSKVLMLDEPTSGMDAVSRRAIWDLLQQQKSDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGSSLFLKQKYGAG--YHMTLVKEPHCNPEGISQLVHHHVPNAMLESHAGAELSFILPKESTHRFESLFAKLEKKQKELGIASFGASVTTMEEVFLRVGKLVDTSMDIQAIQLPALQYQHERRASDWALD--SNLCGVMDPTNGIG-----------ALIEEEEVLVKLNTGLALHCQQFWAMFLKKAAYSWREWRMVAAQILVPVTCLTLALLAINYTSEIFDD---PPLKLSLNEYGTTVVPFSVPGTS-RLGQQLSEHLRDMLQAERQEPRE----VLG---DLEEFLVFRASVEGGGFNERCLVATSFKDSGERTVVTALFNNQAYHSPATALAIVDNLLFKLLCG-------------------------------------------------------------------PRASIEISNYPQPRSTLQVAKDQFNEGRKGFDIALNLLIAMAFLASTFSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLVPSLLLLVVFRAFDVHAFTRDGHMADLLLLLMLYGWAIIPLMYLLSFFFSAASTAYTRLTIFNILSGIATFIVVTIMRIPAVKLEELSRTLDHVFLVLPNHCLGMAVSNFYENYETRRYCTSSEV----ATHYCKKYNIQYQEN-FYAWSTPGIGKFVTSMAASGGIYLTLLFLIETNLLWRLRTFVCAFRRRWTLAELQNRTSVLPEDQDVADERSRVLVPS--LDSMLDTPLIINELSKVYDQRAPLLAVDRISLAVQKGECFGLLGFNGAGKTTTFKMLTGEETITSGDAFVGGYSISSDIGKVRQRMGYCPQFDALLDHMTGREMLVMYARLRGIPERLIDACVENTLRGLLLEPHANKLVKTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLQAKVRSEGKQE---------------------------------------------------------------------VLEEFKAFVDLTFPGSVLEDEHQD--MVHYHLPGCDLSWAKVFGILEKAKEKYGVDDYSVSQISLEQVFLSFAHLQPPTTEDGR------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R420-1", "uniprot_id": "ABCA3_MOUSE", "id": "Q8R420-1", "name": "Phospholipid-transporting ATPase ABCA3", "aln": "---------------MAVLRQLTLLLWKNYTLKKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVPNATVYPDQSIQELPLFFSFP------------------PPGGTWELAYVPSHSDAARTITETVKREFMIKMR-VHGFSSEKDFEDYIRYDNHSSSVLAAVVFEHSFNHSQDPLPLAVKYHLRFSYTRRNYMWTQTGNIFLKETEGWHTTSLFPLFPSPGPREPSSPDGGEP-GYIREGFLAMQHAVDKAIMRYHANTSAQQLFQKLMVITKRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKLKEYMRMMGLNSWLHWSAWFLMFFLFFLIVVSFMTLLFCVKVK-KDIAVLSNSDPSLVLAFLLCFAISSISFSFMVSTFFSKANIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLSCLLS-NVAMAMGAQLIGKFEAKGTGIQWRDLLNPVNVDDNFCFGQVLGMLLLDSALYGLVTWYVEAVFPGQFGVPQPWHFFLMPSYWCGNPRTVVGKE---------------------EEGS-DPEKALRNEYFEAEPEDLVAGIKIKHLSKVFQVGNKDKMGIRDLTLNLYEGQITVLLGHNGAGKTTTMSLLTGLFPPTSGHAYIHGYEISQDMAQIRKSLGLCPQHDVLFDNLTVAEHLYFYAQLKGLSL-QKCPEEVKQMLHILSLEDKRDLRSKFLSGGMKRKLSIGIALIAGSKVLMLDEPTSGMDAVSRRAIWDLLQQQKSDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGSSLFLKQKYGAG--YHMTLVKEPHCNPEGISQLVHHHVPNAMLESHAGAELSFILPKESTHRFESLFAKLEKKQKELGIASFGASVTTMEEVFLRVGKLVDTSMDIQAIQLPALQYQHERRASDWALD--SNLCGVMDPTNGIG-----------ALIEEEEVLVKLNTGLALHCQQFWAMFLKKAAYSWREWKMVAAQVLVPLTCLTLALLAIHYTSEIFDD---PLLKLSLNEYGRTVVPFSVPGTS-RLAQQLSENLRDMLQAERQEPRE----VLG---DLEEFLVFRASVEGGGFNERCLVATSFKDRGELTVVTALFNNQAYHSPATALAIVDNLLFKLLCG-------------------------------------------------------------------PQASIEISNYPQPRNTLQVAKDHFNEGRKGFDIALNLLIAMAFLASTFSILAVSERAVQAKHVQFVSGVHVATFWFSALLWDLISFLVPSLLLLVVFQAFNVHAFTRDGHMADLLLLLMLYGWAIIPLMYLMSFFFSAASTAYTRLTIFNILSGIATFIMVTIMRIPAVKLEELSRTLDHVFLVLPNHCLGMAVSNFYENYETRRYCTSSEL----AAHYCKKYNIQYQES-FYAWSTPGVGKFVTSMAASGGIYLTLLFLIETNLLWRLRTFICAFRRRWTLAELQNRTSVLPEDQDVAEERSRILVPS--LDSMLDTPLIINELSKVYDQRAPLLAVDRISLAVQKGECFGLLGFNGAGKTTTFKMLTGEETITSGDAFVGGYSISSDIGKVRQRMGYCPQFDALLDHMTGREMLVMYARLRGIPERLINACVENTLRGLLLEPHANKLVKTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLQAKVRSEGKQD---------------------------------------------------------------------ALEEFKAFVDLTFPGSILEDEHQD--MVHYHLPGCDLSWAKVFGILEKAKEKYGVDDYSVSQISLEQVFLSFAHLQPPTTEDGR------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99758-1", "uniprot_id": "ABCA3_HUMAN", "id": "Q99758-1", "name": "Phospholipid-transporting ATPase ABCA3", "aln": "---------------MAVLRQLALLLWKNYTLQKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVPNATIYPGQSIQELPLFFTFP------------------PPGDTWELAYIPSHSDAAKTVTETVRRALVINMR-VRGFPSEKDFEDYIRYDNCSSSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFPLFPNPGPREPTSPDGGEP-GYIREGFLAVQHAVDRAIMEYHADAATRQLFQRLTVTIKRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRLKEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFMTLLFCVKVK-PNVAVLSRSDPSLVLAFLLCFAISTISFSFMVSTFFSKANMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCSCLLS-NVAMAMGAQLIGKFEAKGMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYGLVTWYMEAVFPGQFGVPQPWYFFIMPSYWCGKPRAVAGKE---------------------EEDS-DPEKALRNEYFEAEPEDLVAGIKIKHLSKVFRVGNKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGLSR-QKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGELQCCGSSLFLKQKYGAG--YHMTLVKEPHCNPEDISQLVHHHVPNATLESSAGAELSFILPRESTHRFEGLFAKLEKKQKELGIASFGASITTMEEVFLRVGKLVDSSMDIQAIQLPALQYQHERRASDWAVD--SNLCGAMDPSDGIG-----------ALIEEERTAVKLNTGLALHCQQFWAMFLKKAAYSWREWKMVAAQVLVPLTCVTLALLAINYSSELFDD---PMLRLTLGEYGRTVVPFSVPGTS-QLGQQLSEHLKDALQAEGQEPRE----VLG---DLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVNALFNNQAYHSPATALAVVDNLLFKLLCG-------------------------------------------------------------------PHASIVVSNFPQPRSALQAAKDQFNEGRKGFDIALNLLFAMAFLASTFSILAVSERAVQAKHVQFVSGVHVASFWLSALLWDLISFLIPSLLLLVVFKAFDVRAFTRDGHMADTLLLLLLYGWAIIPLMYLMNFFFLGAATAYTRLTIFNILSGIATFLMVTIMRIPAVKLEELSKTLDHVFLVLPNHCLGMAVSSFYENYETRRYCTSSEV----AAHYCKKYNIQYQEN-FYAWSAPGVGRFVASMAASGCAYLILLFLIETNLLQRLRGILCALRRRRTLTELYTRMPVLPEDQDVADERTRILAPS--PDSLLHTPLIIKELSKVYEQRVPLLAVDRLSLAVQKGECFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQRIGYCPQFDALLDHMTGREMLVMYARLRGIPERHIGACVENTLRGLLLEPHANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLRAKVQSEGQQE---------------------------------------------------------------------ALEEFKAFVDLTFPGSVLEDEHQG--MVHYHLPGRDLSWAKVFGILEKAKEKYGVDDYSVSQISLEQVFLSFAHLQPPTAEEGR------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q293-1", "uniprot_id": "A0A8M9Q293_DANRE", "id": "A0A8M9Q293-1", "name": "", "aln": "---------------MAVWQQFGLLLWKNYIQQKRQILVTLVEIALPLLFSAILIVLRQKVSFTNYPNATHYQSFPLNGLPPLLCY----------------------QQLQLAYVPANASVVQQIAQDVQQNLQSCIKNVRGFETEEQFEEFVKTDPESGKILAAIVFEHPFSHDDEPLPLQVSYHLRFTYSPRNAPAREKSELNPNNDMDWHTLSLFPLFQMPGPREQHDPHGGTP-GYYREGFLQVQYAVDRAIMMAYNRSAAMALFDQTQVLLSRFPYPAFIYDVFILAIQNQLPLLLVLSFTYTALNIVRAVVQEKERKLKEYMRMMGLSNWLHWSAWFLMFFLFLSISIFFVTVLFCVKVS-PNGAVLTYSDPTLVFVFLLVFAISTINFSFMISVFFSRANVAAAAGGFIYFLSYLPYVFLWPRYDLLSHAQKVSACLIS-NVAMAMGAQLIGMFEGKGTGIQWHNLFEAVTVDDDFSLAQVIGLLLLDALLYGLVAWYVEAVFPGEYGVPQPWYFFILPSYWCSSPRVAFLKE---------------------KEDEEDAEKASKGEFMEEEPAGLVAGVKIKRLAKVFKVGNKSKEAVRDLTLNMFEGQITVLLGHNGAGKTTTLSMLTGLFPPSSGRAYINGYDICQDMALIRRSLGLCPQHDVLFDNLTVREHLLFYTQLKGYPR-EKIPGEVDRIIRILNLEDKRNAKCKTLSGGMKRKLSIGIALIGDSKVVMLDEPTSGMDPSARRATWDLLQGEKRGRTILLTTHFMDEADLLGDRIAIMASGELQCCGSPLFLKNKYGAG--YHMVIVKDAFCNVSEITRLVHMYVPDATLESSAGAELSYILPKESTSRFELLFAELEMNRDELGIASYGASVTTMEEVFLRVGKLVDSSLDIQAIQLPALQYQHERRSHDWTMDDSSSISGMTDVTDFTDSC---------TMISEDGSNIKLNTGARLYMQQFYAMFLKRALYSWRNWKVMVAQFLVPLIFTVLALVVARSLPSSHSS---PQLRLALKQYGQTHVPVAVEANAGPLASLLAEIYTTQLPSQNAIAAP----NIT---DFSEYVLYNAQREGGAFNEHCVVGAAFRSSD----VIGYFNNQGYHTPATALMLVDNALFKLLAG-------------------------------------------------------------------PNASIQTGNDPMPRNVSETAQSQLSESQTGFAIAINLMYGMASLASTFALLLVSERSVKSKHVQQVSGVYLTNFWFSALLWDLINFLLPCLLMLVVFRVFSVKAFVAQNHLVDVLFLLLLYGWAVIPLMYLMSFLFSTAATAYTRLTIFNIISGTATFLAVTIMTIPELNLLHLSHLLDKVFLIFPNYCLGMSFTEFYQNYEMITFCTSSPL----AKYICKYYNITYQMN-YFSMEEPGVGRFLVALSLQGVVFIILLFLIELRCIR----LLLNLCRRRKKALLLAEEALQPEDRDVAEERKRVLECQPVVESMVGSPLVVQELSKMYSGGQSLLAVDRLSLAVGKGECFGLLGFNGAGKTTTFKMLTGDESITSGDAFIDGYSILTDVKKVQQRIGYCPQFDAVLDHMTGRETLSMYARLRGIPEKYVTACVENVLRSLLLEPHADKLVRSYSGGNKRKLSAGMALIGGPPVIFLDEPSTGMDPVARRLLWDAITRTRESGKAIIITSHSMEECEALCTRLAVMVNGQFKCLGSPQHLKSKFGSGYTLLAKVRVETELEE-------------------------------------------------------------------SDLQLFKDFIESTFPGSLLKDEHQG--MVHYHLTDKTLTWAQVFGVLETAKEKYSIEDYCVSQISLEQVFLSFAQFQHCAEACRK------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVK6-1", "uniprot_id": "Q9VVK6_DROME", "id": "Q9VVK6-1", "name": "ABC transporter domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLADGSYP--LYKTGFLAVQQALSQVHIKHKCKEFNKTQGDIKFPPIKDLPSPPIFKSDNSSTLQDVGIMIIVIIIFFVVVSLTKSIVEEKELQLKVTLNLMGVGSCLQWVAWYIQTFIIFLIGSSIITLFWKLVLPNSEISFMPFTHWSMALFVLLVLSHCTICFSFLMSSLISTTYRISLVTFLALIATYLPFLILHSKGCSEGLNVFLSLFLLS---GLQVLVVGICMWEDYGEGLQWGNLFETSWPGGTLSVGYILLVMILASFLSLLLCLYLEKIRPGPYGVPQPWHFPCTRCCSTESLLPYSRLFN----------------RIFGIYSAAPDEERPDLQLIEPDPVDKIAGVQIRGLSKTFGK----MEVVKNVSFDMFEGQITVLMGHNGAGKTTLISMLAGFISPTSGTALINGFDIRQERRQAQRCIGLCPQQNVLFKHLSSVSHIQLFSRLRGLRG-AEVKSEVQNYLKKLNLQEKKRLAARNLSGGTQRRLSVACSLCGGVKVLICDEPSTGLDPSARRELWRLILEAKEGCTILLTTHQLDDGEVLGDRVVIISDGQLRCIGSLPFLKKQVDAS--CLITCEARKRCDLEKLTSLISRHVGTIQPFSIKGRDVCYKLPLSKSKYFSSLFRDLESQMNILGVRGFSLSSVSLEEIFMSFGAEDLNSRQSG--------GAEKRDDDD---------------------------------RDDDEENEVQDGNVRSCKKQWRAMMTKKVMALYDNKVYFLLLLLTPIVYYITTLMMATKP-HHSGR---PTFNISDYGVDKFTILLSVPVSKSYTEERRADSIASLIKGKLKLIVV----SEQ----IKDYVDDKWKSREGRR-EINFVSMAIDTGDRTGLIGWVGPRHYVHAAPMILNLVYNALAQELIG-------------------------------------------------------------------PKISIEVTSVPFTLRKKEDFLISNNG-----DIPIYVIGYVSIAMIIFSSAVIQERVSHMKMLQEVSGLEMITYWLSHLAFDMVVFFILVLALLLPLYGYAPWYLLLCVLFFTGLAGLIFIYFLISMLSATFLAVSMILLSVIIGSLILMILGALALIFKMVYVAIYVANMHPLIAGYNCIQKCFHYMSLCGSYISEAQNPLSENLTSDEMY----------CINPLAFLEPRCVCVNPMTWPDMLVMLGTAIILFLLIMFFEYGSCVWYRCKGCCPYSSKG----------SIEDPKVSREAEKIRAMD--ADQIGTRALVVNGVSKKYG--CDQLAVNNISFALKPSHCVGLLGPNGAGKTTTFKMIVGEHSIDKGNIYISGYSMRMKRNKAMKELGYCPQSDSFFEFLTGRQLLKVFLLIWGFPSKDLNKRCEKLADQFGFRKHLDKKITYYSGGTKRKINAAVACGAN-SLICLDEPSAGVDPASRRHVWTIINEVAQQGKAVLLTSHNMDEINALCSKSVILVDGSIYAMGSVQHVKNKIAKGMTLKLVVNVQPDNMVA-------------------------------------------------------------------MLTKIEDDIYMTYPNAELKEKYEFS-GRLTFQISKDTSWSEIFEYVEGNRSSWHLEDYSLSQPSLEDAFEEIAEERRKKKSNQS------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDR4-1", "uniprot_id": "Q9VDR4_DROME", "id": "Q9VDR4-1", "name": "ABC transporter domain-containing protein", "aln": "-----------MNRNLTYCQKYRLLLWKDIKLQLTNWVELVMIIFLSALMPIFFSIGTKVAKSIFPPDIEMEKSPGPKSVN------------------------------TSLFVDLYFTPNNGILEQLITQLANISEFKSVEVFDTNSELYLQLMINRN------------------------------------------AIGIAFPSEWYDIKSCPEVLNLTIFMPLSIK-RKDFKYFESGFLLLQERISKIFIFFKN----AGNGKIPRVLMNHFPYPSYVPN-HYAESAKAMTYMTLISFFLPCITIAKYVVAEKERHQKAVLTAMGFSNSIHWLAWYTKSMLLLLLCLLIMISIFSIGLI------YEFSSLVCLMTIFLVYIHSLVLFAFFISSFFSRSLSAVVATILMYFSTALPFLIVGAENSSVAAQTAASIGLNS---ALFYILDSVAVMEMQSVGAQWYTIDNTASSGYKLSIVGYMLIMISISWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYWCPLRYGSSVFHQGALLPLAGKNSEGNLPAAHPTRQPIIYLDDRTQENFQRVNISKKIGIEVRSLSKTFGFR----NVVKDLFFNVYENEITALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEAKVAKSSLGICPQHSVIFKGMSARDHIYFFSRVKGYNK-TEAMMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACALCAGSKVILCDEPSSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQILCYGTLGYLKQLPFTS--YTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHGVDVSYKLPRSQIDRFPEFFQQLEENKKSLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGVNDKVEFGVQTDKAIRTKDRANNSLVRYQHQVDPPNETILNTKTPINPIEIWRPIDREKGSCMAQWQAMFIKKKNYTASRALIFILILIIPLFYYIIVLGTAASEKCAHRTDKQPVLPLSLDYYSYDDMIILLEVDKQLYKSEGEAYVQLVKEPATVESVDSIFS----------HLLKAPPIIRRDIKRKYVCGASFNNAS--TITAWFNSDAFEHSAPIALNLVYNALGKAVFEDQDFSILVNRGDLHDFIWLNNASSMRRRYKRQNDPDYTDYSDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNIITVQMSIIEAASTLYNEKGKRKQLFGTLIIITAYIALCLSIFSIFVTKERVEHFKMQQEIYGVTLFYFWSTHFVGDFLIYAIYMGALTIAIYHFTIWY--------QVVVMLLLIGFACLPFVYLCSLLFSLPNIAFAGIFAILVMTGGMLFSFMYMLTLITDVNFTTVFAILPMYVGTFGLFKCLAWREYCNREVLPPIEELDCK--------------FGNCNVFCACKPERTWMEVWLLMVHCLVWFIFLWFSNFGYEIGYRFKPKLSNRIWHN---------NEKHIRVLDEERRVGLIP--KYEHEDYPIIVDQVTKNYCR--AKNAVQLVSFAIRPGDTFGLLGAQGAGKTSIFQMIAGETSMSHGNIYVRGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIHCLLHGVPKDHIKAVSEQMAIEFNFKDQLDRPIHTYSGGKKRKLNIALAIDSG-SVLCLDDTNGSVDHATQRFIWRKLEAVKRSGRPVLLTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTIVIRLRVNPSDGKLKR-------------------------------------------------------------------RFQQLIADMAELFPLATLHEALET--CLIYHININVTTLANLFYQMEKIRNEGLLEDYSITQVSLDEIYRILNDEEDPNLVDLDSTHNSEVLEDIRDTTRDTTRGTTRDTNLVSDEGIQKEKVKRKKVEEEDRDRQESTETSKPKVKRSPATQSDSTDTDEMEVEKGEKLKKKTSTFFQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBS3-1", "uniprot_id": "A1ZBS3_DROME", "id": "A1ZBS3-1", "name": "ABC transporter domain-containing protein", "aln": "-----MSSGESPVKTQSSICLLWLVICKTARFQFSNTLTSVIIIVGPIVVFLVYAATALFREPQEETSVKYPPVN-----------------------------------ITTKVPYIYYSPENLVLAAVIEDVVHDLKAVGSKAFASASELNKALIGKDTYGYVGIEFDDSFSDIN------------------------ELPINVTVGLRFPLHLRKNPKMVWDNTSILKHSKMDVDYYQVEGFLVVQAKLSEALIRAKN-----EAVVLPEVILQHYP---DVAEVDRLDNRVALGGVLFLPVTISAAYLAQMIVMERRDHLRDMLELMGVRAWIYWLSWFLVAFLLLSIPTVFMVLLLKWRYF-------SLSDSSLVLFFLLVYNLEVLTSAFMISSFFSDTVGVQVAIVIVHLIGCLPWRLLLMGYVPTLPRTIFVCLFLN--SSLAMGLQQFIKSENLRLGLHWTYLFERTDWDEFVHLGPILLFMLFGCLLRILVLAYMEQLRSYQN---RKWYFPVQPSFWCRWNRRPRSDD-------------------------------FDVEGQETGIRGHPLIVRARNIEKVFNEW----IAVKDLNLNFYQDEITVFLGHNDSGKSTILMLLAGFLRPSAGEITINGYDLATNQRKARQSMCICPQPNVLFEKVNARWHLQFYCRLKGLNR-QEASAETDKYLEIGRLQDFANTKVKNLPSGIKRMLMLCCNLCGNSKILLLDEPGTSMDPAMRSNMWDLLRRERKGRCIIMATHNMNEAEVVADQIVVLCDAQVIGYGTTGFLTQIAGTGSSYLLICTKMDTCIVAEVTNFLQIRFPDIKLHNEFSIYVTYELPTKYVQQYAALFLELEEALGELNLAEISVCAPTLGSVFLQMGEEMRQSWNRISSFDLLSSPSPMLSLLN----------------------------------LLPTFEVREDDGRVKCCNQWRAIVEKKRLFTLRHQKFYCMIIATPIIICLLIISFSIFIFLVDHHLS-ELLVTDLSIYPKAVFVIDSPAEGNRFERHYMANVIGQGGTVRSTSGTP----------IDDYLLAEMESDQVKVQHTFLAGATFDSNAN--SIIAWSNNKLKHGSALSMGLVYAAIGQELAK---------------------------------------------------------------------LDIRIVNKPYQDTVQQAVRGLIYAS--TIEFAVLVFHYLVLGTAIFAVLPIVERRSKVQHQQFSSGMSRSTYWLSHLSWDYCFYIAMILPLIVVAG-------ITIGSVLPVIVQLLAFGFSAISFTYLLCLMSNDFGKMFSIILYINMIG-------VLALFIHPKSPQTRYAVIESVLLVHPHYSLCCGMYEAIR-------------------------------------MSTFSLKQLPYLIFSGAAYLTIVVFAWVPRRLNYVFKSIRNEKIYP--------SYKDEDKEVDKMRRRLAYLT--TAHYAFFPLILKNLSKRYG---SFVAVRSLTLDLNPFECVGLLGRNGSGKSSIFRMIVGMESITVGSIHIKGYSLKTRPKDASRHVGFCPRELMLLSFMTGKDALRFCCLINGIRREYIKSLVASLAECFELVPHMNKRISTYSNGTKRKLMIAMGTLAP-SLMCLDEPTAGVDMHAKYEIWSILDGIRQGGRSILLTTHNLEECEFLCTNVGIMDHGSLLCYGSLSRLKHRFNMGIFVKVKMGTRAEMDDERDNWMQITMMPPNDSEMGSTVGARRMMLAHLLRHHNPPVEPVKKSRTSRAQPDTTNSELNMRKDYEALLQELEEVFKKDHPYSTVSEKYSYRGMITFCIPRGQIKWSAIFEYMENLKDEMQILYYSVSHTTFQDVFMKFVRKQNQ------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :* : : . * . : .: . : : :. *:. : : : :*. : * :*: :: : :: : : . .: : .*::: ::* : : : *: : : .: . * * * : . . . : : . : : *:* : . : * : : :. : * : ::.: :.....:**.::**:.:**:* : :: *:. *::* : * :: . : .: :*** .::*. :. *: :: :::* * : * : *. * :* * : * .. *::: *** :.:*. * :: : . ::::*: :::.:::.*::.:: ..:: *: :*.: :. : . :: :: . . : : ** . : :: .*: * : . :: ::: .. : : *:. *: . *: : : . .: . . :. * .. : :: : : . : : : ** : : * *: :* : : * : : *: : : . : . : . . : : :: . .. * : ::: ::* * ** ::: : . .**** :*:**:: *:*:.* : * .: * : :*:**: . :**:: * . : *. : : : : :: **.*.:**: .:. . .:: **:.. .:* :: :* : *:.:::*::.::* : :*:. .: *.: ** . :: .. : : : . . * : : : . . : :* :* . : * : : ::: : : . ", "identical_positions": 112, "similar_positions": 340, "identity": "5.51%" }, { "cls_id": "homologset.agr.HGNC:330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAG1-1", "uniprot_id": "F1MAG1_RAT", "id": "F1MAG1-1", "name": "Agouti-related protein", "aln": "-MLTAMLLSCVLLLALPPTLGVHMGVAPLKGIRRSDQALFPEFSGLSL----KKTAADRAEDVLLQKAEALAEVLDPQNRESRSPRRCVRLHESCLGQQVPCCDLCATCYCRFFNTFCYCRKLGTGTTNLCSRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56473-1", "uniprot_id": "AGRP_MOUSE", "id": "P56473-1", "name": "Agouti-related protein", "aln": "-MLTAMLLSCVLLLALPPTLGVQMGVAPLKGIRRPDQALFPEFPGLSLNG-LKKTTADRAEEVLLQKAEALAEVLDPQNRESRSPRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGT-ATNLCSRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00253-1", "uniprot_id": "AGRP_HUMAN", "id": "O00253-1", "name": "Agouti-related protein", "aln": "-MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQALLPELPGLGLRAPLKKTTAEQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGT-AMNPCSRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P467-1", "uniprot_id": "A0A8M1P467_DANRE", "id": "A0A8M1P467-1", "name": "Agouti-related protein", "aln": "MMLNTVIFGWFLVNVVVMASHPHLRRRENSFILTSDTDSLPEMEHLEIN-----SAEEKILEDLEAYDEDLGKAVHLQRRGTRSPSRCIPHQQSCLGHHLPCCNPCDTCYCRFFKAFCYCRSMDNTCKNEYA--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.: ::. *: .: : :: . * .* :**: * : :: :: : * : *.:.:. * * .**. **: ::****:::***: * *******::*****.:.. * : ", "identical_positions": 37, "similar_positions": 43, "identity": "27.61%" }, { "cls_id": "homologset.agr.HGNC:3300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63241-1", "uniprot_id": "IF5A1_HUMAN", "id": "P63241-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MAD-DLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDG-YLSLLQDSGEVREDLRLPEGDLGKEIEQKYDCGEEILITVLSAMTEEAAVAIKAMAK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63242-1", "uniprot_id": "IF5A1_MOUSE", "id": "P63242-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MAD-DLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDG-YLSLLQDSGEVREDLRLPEGDLGKEIEQKYDCGEEILITVLSAMTEEAAVAIKAMAK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3T1J1-1", "uniprot_id": "IF5A1_RAT", "id": "Q3T1J1-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MAD-DLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDG-YLSLLQDSGEVREDLRLPEGDLGKEIEQKYDCGEEILITVLSAMTEEAAVAIKAMAK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NX89-1", "uniprot_id": "IF5A1_DANRE", "id": "Q6NX89-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MADPDLDFASGDAGASATYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTNKKYEDICPSTHNMDVPNIKRNDYQLVDISEG-FLSLMMDNGDVREDLRVPDGDLGKEIENKFAAGEEMLVTVLSAMGEESAVALKPMTK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GU68-1", "uniprot_id": "IF5A_DROME", "id": "Q9GU68-1", "name": "Eukaryotic translation initiation factor 5A", "aln": "MAELDDQFETTDSGASTTYPMQCSALRKNGFVMLKSRPCKIVEMSTSKTGKHGHAKVHMVGIDIFSNKKYEDICPSTHNMDVPNVKREDLQLIAISDDSFLTLMTESGDLREDLKVPEGELGEQLRLDFDSGKDLLCTVLKACGEECVIAIKTNTALDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23301-1", "uniprot_id": "IF5A1_YEAST", "id": "P23301-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MSDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDG-FLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19211-1", "uniprot_id": "IF5A2_YEAST", "id": "P19211-1", "name": "Eukaryotic translation initiation factor 5A-2", "aln": "MSDEEHTFENADAGASATYPMQCSALRKNGFVVIKGRPCKIVDMSTSKTGKHGHAKVHLVTLDIFTGKKLEDLSPSTHNLEVPFVKRSEYQLLDIDDG-YLSLMTMDGETKDDVKAPEGELGDSMQAAFDEGKDLMVTIISAMGEEAAISFKEAPRSD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : * . *:*:*:*:*************::*.******:***************:* :***:.** **:.*****::** :**.: **: *.:. :*:*: .*: ::*:: *:*:**..:. : *:::: *::.* **..:::* . ", "identical_positions": 75, "similar_positions": 56, "identity": "47.17%" }, { "cls_id": "homologset.agr.HGNC:3301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GZV4-1", "uniprot_id": "IF5A2_HUMAN", "id": "Q9GZV4-1", "name": "Eukaryotic translation initiation factor 5A-2", "aln": "MAD-EIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDG-YLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V7J7-1", "uniprot_id": "G3V7J7_RAT", "id": "G3V7J7-1", "name": "Eukaryotic translation initiation factor 5A", "aln": "MAD-EIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDG-YLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGY2-1", "uniprot_id": "IF5A2_MOUSE", "id": "Q8BGY2-1", "name": "Eukaryotic translation initiation factor 5A-2", "aln": "MAD-EIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDG-YLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NX89-1", "uniprot_id": "IF5A1_DANRE", "id": "Q6NX89-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MADPDLDFASGDAGASATYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTNKKYEDICPSTHNMDVPNIKRNDYQLVDISEG-FLSLMMDNGDVREDLRVPDGDLGKEIENKFAAGEEMLVTVLSAMGEESAVALKPMTK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GU68-1", "uniprot_id": "IF5A_DROME", "id": "Q9GU68-1", "name": "Eukaryotic translation initiation factor 5A", "aln": "MAELDDQFETTDSGASTTYPMQCSALRKNGFVMLKSRPCKIVEMSTSKTGKHGHAKVHMVGIDIFSNKKYEDICPSTHNMDVPNVKREDLQLIAISDDSFLTLMTESGDLREDLKVPEGELGEQLRLDFDSGKDLLCTVLKACGEECVIAIKTNTALDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23301-1", "uniprot_id": "IF5A1_YEAST", "id": "P23301-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MSDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDG-FLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19211-1", "uniprot_id": "IF5A2_YEAST", "id": "P19211-1", "name": "Eukaryotic translation initiation factor 5A-2", "aln": "MSDEEHTFENADAGASATYPMQCSALRKNGFVVIKGRPCKIVDMSTSKTGKHGHAKVHLVTLDIFTGKKLEDLSPSTHNLEVPFVKRSEYQLLDIDDG-YLSLMTMDGETKDDVKAPEGELGDSMQAAFDEGKDLMVTIISAMGEEAAISFKEAPRSD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : * . *:*:*:***************::*.******:***************:* :***:.** **:.*****::** :**.: **: *.:. :*:*: *: ::*:: *:*:**..:. : *::: ::: * .** .:::* ", "identical_positions": 75, "similar_positions": 52, "identity": "47.17%" }, { "cls_id": "homologset.agr.HGNC:3308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00773-1", "uniprot_id": "CELA1_RAT", "id": "P00773-1", "name": "Chymotrypsin-like elastase family member 1", "aln": "------------------MLRFLVFASLVLYGHSTQDFPETNARVVGGAEARRNSWPSQISLQYLSGGSWYHTCGGTLIRRNWVMTAAHCVSSQMTFRVVVGDHNLSQNDGTEQYVSVQKIMVHPTWNSNNVAAGYDIALLRLAQSVTLNNYVQLAVLPQEGTILANNNPCYITGWGRTRTNGQLSQTLQQAYLPSVDYSICSSSSYWGSTVKTTMVCAGGDGVRSGCQGDSGGPLHCLVNGQYSVHGVTSFVSSMGCNVSKKPTVFTRVSAYISWMNNVIAYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X79-1", "uniprot_id": "CELA1_MOUSE", "id": "Q91X79-1", "name": "Chymotrypsin-like elastase family member 1", "aln": "------------------MLRFLVFASLVLCGHSTEDVPETDARVVGGAEARRNSWPSQISLQYQYGGSWHHTCGGTLIRSNWVMTAAHCVDSPMTYRVVVGEHNLSQNDGTEQYVNVQKIVSHPYWNKNNVVAGYDIALLRLAKSVTLNNYVQLGVLPREGTILANNSPCYITGWGRTRTNGELAQTLQQAYLPSVSYSICSSSSYWGSSVKNTMVCAGGDGVRSGCQGDSGGPLHCMVNGQYAVHGVTSFVSSMGCNVARKPTVFTRVSAYISWMNNVIASN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNI1-1", "uniprot_id": "CELA1_HUMAN", "id": "Q9UNI1-1", "name": "Chymotrypsin-like elastase family member 1", "aln": "--------------------------MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRR3-1", "uniprot_id": "A0A8M9PRR3_DANRE", "id": "A0A8M9PRR3-1", "name": "pancreatic elastase", "aln": "MMETFRDQTSRKTRNMLRILLLSVLATLVLAEPRYLEDIDIEGRVVGGEVAKPNSWPWQISLQYLSGSSYYHTCGGSLIRPGWVMTAAHCVDSPRTWRVVLGDHDIYNHEGREQYISVSRAHIHPNWNSNSLSSGYDIALLELSSDASLNSYVQLAALPPSGQVLPNNNPCYISGWGRTQTGGSLSAELKQAYLPVVDHDTCSRSDWWGSTVKNTMICGGDGT-LAGCHGDSGGPLNCQVSGQYVVHGVTSFVSSAGCNTNKRPTVFSRVSAYISWINDVSTIH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P7N7-1", "uniprot_id": "A0A8M1P7N7_DANRE", "id": "A0A8M1P7N7-1", "name": "pancreatic elastase", "aln": "---------------MLRILLLSVLATLALAEPRYLKDIAIEERVVGGEIAKPHSWPWQISLQYSDLGTYYYYCSGTLIRPGWVMVAAHCVEALRKWTVALGDHDIYTHEGPEQYISVSEVFIHPNWNPNNVAFGYDIALLRLSIDATLSSYVQVATLPSSGEILPYGHTCYITGWGYTETGGSLSAQLKQAYMPVVDYETCSQKDWWGSSVKETMICAGGTTSMSACHGDSGSPLNCLFNGKYVVHGVTSFVSPEGCNTYKKPTGFTRVSAYINWINQIISEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* . : ***** * :*** ****** .: :: *.*:*** .***.*****. .: *. *:*:: ::* ***:.*.. ** ** :.: *******.*: ..:*..***:..** .* :*. . .***:*** *.*.*.*: *:***:* *.: ** ..:***:** **:*.*. :.*:****.**:* ..*:* *********. ***. ::** *::*****.*:*:: : ", "identical_positions": 117, "similar_positions": 78, "identity": "41.2%" }, { "cls_id": "homologset.agr.HGNC:3309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A488-1", "uniprot_id": "D4A488_RAT", "id": "D4A488-1", "name": "", "aln": "MQPTMALHR-PSNQTLASMLLALLLVCPALASEIVGGRPAQPHAWPFMVSLQRRGGHFCGATLIARNFVMSAAHCVNGRNFQSVQVVLGAHDLRRREPTRQIFSVQRIFENGFDPSRLLNDIVIIQLNGSATINANVQVAELPAQGQGVGNRTPCVAMGWGRLGTNRPLPSVLQELNVTVVTNLCRRRVNVCTLVPRRQAGICFGDSGGPLVCNNLVQGIDSFIRGGCGSGFYPDAFAPVAEFADWINSIIRSHDDRPLTNPKDREREGRTN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UP87-1", "uniprot_id": "ELNE_MOUSE", "id": "Q3UP87-1", "name": "Neutrophil elastase", "aln": "----MALGR-LSSRTLAAMLLALFLGGPALASEIVGGRPARPHAWPFMASLQRRGGHFCGATLIARNFVMSAAHCVNGLNFRSVQVVLGAHDLRRQERTRQTFSVQRIFENGFDPSQLLNDIVIIQLNGSATINANVQVAQLPAQGQGVGDRTPCLAMGWGRLGTNRPSPSVLQELNVTVVTNMCRRRVNVCTLVPRRQAGICFGDSGGPLVCNNLVQGIDSFIRGGCGSGLYPDAFAPVAEFADWINSIIRSHNDHLLTHPKDR--EGRTN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08246-1", "uniprot_id": "ELNE_HUMAN", "id": "P08246-1", "name": "Neutrophil elastase", "aln": "----MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRR-SNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* * : **.:* **:* .********** *:*******.*** ************ ********** . *.::*:******:* *:* *** *:********:** .*******:***************:*****: :*: . *:***** ** ** .************.:*** ****** ****:******.*****.*::** **:****.**:*********:*.:**:***: :*. .:*:* .**:", "identical_positions": 182, "similar_positions": 48, "identity": "66.91%" }, { "cls_id": "homologset.agr.HGNC:33100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7B7-1", "uniprot_id": "GPX8_MOUSE", "id": "Q9D7B7-1", "name": "Protein peroxidase GPX8", "aln": "MEPFAAYPLKCSGPKAKIFAVLLSMVLCTVMLFLLQLKFLKPR-TNSFYSFEVKDAKGRTVSLEKFKGKASLVVNVASDCRFTDKSYQTLRELHKEFGPYHFNVLAFPCNQFGESEPKSSKEVESFARQNYGVTFPIFHKIKILGPEAEPAFRFIVDSSKKEPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPW7-1", "uniprot_id": "D3ZPW7_RAT", "id": "D3ZPW7-1", "name": "Glutathione peroxidase", "aln": "MEPLGAYPLKCSGPKAKIFAVLLSMVLCTVMLFLLQLKFLKPR-INSFYSFEVKDAKGRMVSLEKFKGKASLVVNVASDCRFTDKSYETLRELHKEFGPYHFNVLAFPCNQFGESEPKSSKEVESFARKNYGVTFPIFHKIKILGPEAEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TED1-1", "uniprot_id": "GPX8_HUMAN", "id": "Q8TED1-1", "name": "Protein peroxidase GPX8", "aln": "MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPK-INSFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQVIIKKKEDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV14-1", "uniprot_id": "GPX8_DANRE", "id": "Q7ZV14-1", "name": "Probable glutathione peroxidase 8", "aln": "MEALGGYPSKSSASRAGLFKVLLSVALCMGSLYLLQNKLSKSRKTKDFYSYEVKDARGRTVSLEKYRGKVSLVVNVASGSELTEQSYRALQELHRELGTSHFNVLAFPCSQYGDTESGTSREIEAFAKSNYGVTFPIFNKIKIMGSEAEPAFRFLTDSVQKIPRWNFWKFLVSPEGQVVRFWKPEEPVSDIRKEATTLVRNIILKKRQEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:..** *.*..:* :* ****:.** *:*** *: *.: :.**::*****:** *****::**.********...:*::.* *:***:*:*. **.******.*:*::*. .*:*:*:**:.*********:****:*.*.******:.** :* *******:**.******:**:****:. ** . : :: ::*:**:::*", "identical_positions": 119, "similar_positions": 69, "identity": "56.67%" }, { "cls_id": "homologset.agr.HGNC:33104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80YP6-1", "uniprot_id": "ZIK1_MOUSE", "id": "Q80YP6-1", "name": "Zinc finger protein interacting with ribonucleoprotein K", "aln": "-------------MTAEMDMALMQGCVTFQDVAICFSHEEWRLLDETQRLLYLSVMLQNFALINSQGCGHKTEDEERRVSTRASKGLR-SETTP---KTNLCEKCVPILQDILCLPGLPGQK-HSTEASSKVDQHQDHNSTGKPLEKNADRSSY----LFYLSAKSFPSWDVEKDLPDILSLLKSQVCPKTKKYRKSTEGRKET-SHESD-KSEECQSLSSQKQTLAHHPKTSNGKKLYECSKCGKTFRGKYSLDQHQRVHTGERPWECRDCGKFFSQTSHLNDHRRIHTGERPYECSECGKLFRQNSSLVDHQKTHTGARPYECSQCGKSFSQKATLVKHKRVHTGERPYKCSECGNSFSQSAILNQHRRIHTGVKPYECRECGKSFSQKATLIKHQRVHTGERPYKCSECGKSFSQSSILIQHRRIHTGARPYECSQCGKSFSQKSGLIQHQVVHTGERPYECDTCGNSFSQCSSLIHHQKCHNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RA43-1", "uniprot_id": "M0RA43_RAT", "id": "M0RA43-1", "name": "Zinc finger protein interacting with ribonucleoprotein K", "aln": "-------------TTAEVDMALMQGCVTFQDVAISFSHEEWRLLDETQKLLYLSVMLQNFALINSQGCGHRTEDEERRVSTRASKVLR-SETVPFTQKSHLCEKCVPILQDILCLPGLPGQK-HSIEASSEVDQHQNHNTTGKPLKKNADKASY----LFYLSAKSFPSWDVEKDLPDILSLLKSQVCPKTKKPRKSTDDRKET-SHESH-MSEECQRLSSQKQTFAHHPKASNGKKLYECSKCGKTFRGKYSLDQHQRVHTGERPWECRDCGKFFSQTSHLNDHRRIHTGERPYECNECGKLFRQNSSLVDHQKTHTGARPYECSQCGKSFSQKATLVKHQRVHTGERPYKCSECGNSFSQSAILNQHRRIHTGVKPYECRECGKSFSQKATLIKHQRVHTGERPYKCSECGKSFSQSSILIQHRRIHTGARPYECNQCGKSFSQKSGLIQHQVVHTGERPYECDTCGNSFSQCSSLIHHQKCHNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3SY52-1", "uniprot_id": "ZIK1_HUMAN", "id": "Q3SY52-1", "name": "Zinc finger protein interacting with ribonucleoprotein K", "aln": "MAAAALRAPTQVTVSPETHMDLTKGCVTFEDIAIYFSQDEWGLLDEAQRLLYLEVMLENFALVASLGCGHGTEDEETPSDQNVSVGVSQSKAGSSTQKTQSCEMCVPVLKDILHLADLPGQKPYLVGECTNHHQHQKHHSAKKSLKRDMDRASYVKCCLFCMSLKPFRKWEVGKDLPAMLRLLRSLVFPGGKKPGTITECGEDIRSQKSHYKSGECGKASRHKHTPVYHPRVYTGKKLYECSKCGKAFRGKYSLVQHQRVHTGERPWECNECGKFFSQTSHLNDHRRIHTGERPYECSECGKLFRQNSSLVDHQKIHTGARPYECSQCGKSFSQKATLVKHQRVHTGERPYKCGECGNSFSQSAILNQHRRIHTGAKPYECGQCGKSFSQKATLIKHQRVHTGERPYKCGDCGKSFSQSSILIQHRRIHTGARPYECGQCGKSFSQKSGLIQHQVVHTGERPYECNKCGNSFSQCSSLIHHQKCHNT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* .* * :*****:*:** **::** ****:*:****.***:****: * **** ***** . ..* : *:: . *:: ** ***:*:*** *..***** : .:: .***.*::: *.*::: *::** ** :* *.* .*:* **** :* **:* * * ** . *: :: *::*. * ** * :*:* .:**:. .************:******* **************.:**************************.***************** *************************:***********.*********************.***** :**************************.:**************************.***************************:.*******************:", "identical_positions": 334, "similar_positions": 75, "identity": "68.58%" }, { "cls_id": "homologset.agr.HGNC:33107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB44-1", "uniprot_id": "D3ZB44_RAT", "id": "D3ZB44-1", "name": "", "aln": "MPRSPARRAPPPLQIPMAVTWPLTDPARGLMAFEDVAVYFSQEEWMFLNAAQRALYRHVMLENFALVDSIGPSVSRPRVIIQLQRGEEPWVPNRTIAGPGRGTHRRSSLGSNYSARDRHVSGASPGATCDRPVRISTSLLPPAGAYPDAKILEGHQSACPSLQKKPTGVSVIYWEQLLLGSSSSEATVSLRLTSPVGVPENGSSRVKAFSDLLAPGKQLRVAEQQKPEMQLNPGRTFQSIPDLHEAEEGHG--ISGACHESQGDPSVPEAPIWDELGEALQAGPGLFSGDKPFECRACNKVFVKSSDLLKHLRTHTGERPYECAQCGKAFSQTSHLTQHQRIHSGETPYVCMVCSKAFRHSSSLVRHQRIHTVEKTFHCNECGKAFSHGSNLSQHRKIHAGGRPYACAQCGRRFCRNSHLIQHERTHTGEKPYACSLCGAAFSQGSSLFKHQRVHTGEKPFSCPQCGRAFSHSSNLTQHQLLHTGERPFRCGDCGKAFAKGAVLLSHRRIHTGEKPFVCTQCGRAFRERPALFHHQRIHTGEKALRRPRGNMHSQIGSLGVSLDGTHPKATLDPPAVPNIAEA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AW86-1", "uniprot_id": "Z324B_HUMAN", "id": "Q6AW86-1", "name": "Zinc finger protein 324B", "aln": "------------------------------MTFEDVAVYFSQEEWGLLDTAQRALYRHVMLENFTLVTSLGLSTSRPRVVIQLERGEEPWVPSGKDMTLARNTYGRLNSGSWSLTEDRDVSGEWPRAFPDTPPGMTTSVFPVADACHSVKSLQRQPGASPSQERKPTGVSVIYWERLLLGSRSDQASISLRLTSPLRPPKSSRPREKTFTEYRVPGRQPRTPERQKPCAQEVPGRAFGNASDLKAASGGRDRRMGAAWQEPHRLLGGQEPSTWDELGEALHAG------EKSFECRACSKVFVKSSDLLKHLRTHTGERPYECTQCGKAFSQTSHLTQHQRIHSGETPYACPVCGKAFRHSSSLVRHQRIHTAEKSFRCSECGKAFSHGSNLSQHRKIHAGGRPYACAQCGRRFCRNSHLIQHERTHTGEKPFVCALCGAAFSQGSSLFLHQRVHTGEKPFACAQCGRSFSRSSNLTQHQLLHTGERPFRCVDCGKGFAKGAVLLSHRRIHTGEKPFVCTQCGRAFRERPALLHHQRIHTTEKTN-AAAPDCTPGPG----FLQGHHRKVRRGGKPSPVLKPAKV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:************* :*::**************:** *:* *.*****:***:********. . .*.*: * . ** :.**.*** * * * * ::**::* *.* ..* *: : .*.** ::***********:***** *.:*::*******: *:.. .* *:*:: .**:* *..*:*** * ***:* . .**: *. *:. :..* :*.: . *.. ********:** :*.******.************************:*************************.* **.*****************.**:*:*.****************************************************:.*:************* ***********:*.****:**:******************* ****.***********************************:******* **: . : . * *:* * *. . . * : * ", "identical_positions": 371, "similar_positions": 94, "identity": "63.42%" }, { "cls_id": "homologset.agr.HGNC:33109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q2S6-1", "uniprot_id": "E9Q2S6_MOUSE", "id": "E9Q2S6-1", "name": "", "aln": "MANSNSQDMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRDMMLETYSNLVAVVGRCISKPDLIVLLEQEKEPWMAVKEETDRPSPD--------------------------LETDYDAENISPENPINNKKFLKQSIKQL-ITFDPKDSST-SIGPNYSTFHGLQDCQS-DAGQQITNKEGVPPHTCQTLAHNTEKPYECKECGKCFGCRSTLTQHQSIHTGEKPYECEECGKAFRLPQQLTRHQKSHSGEKPFECNECGKAFHLPDLLKYHKTIHTGEKPFECRECGKSFNRVSNLVAHRIIHADVKPYKCSECGKAFKRRSNLVQHQKTHSDERPFQCKDCGKGFIVLAQLTRHQNIHTGEKSFECHECGKAFRLPQQLTRHQKSHSGEKPFKCNECGKAFHLPDLLKYHKTIHTSTKPFECRECGKSFHRISNLVEHRLIHADVKPHKCNECGKAFKRSKSLMQHQKIHSGERPFQCQECGKAFIVLTHLTRHQTIHTGEKSFECNECGKKFRTATHLVMHQTIHTGEKPFECNVCGKAFRLQVYLSEHQKIHIEEKPFKCKLCGSAFRRKYQLNEHYTIHTDEKPYQCKECGKCFRQRSNFTEHQSIHTGNKPFECKECGKFFRLNTLLIRHQKSHSSERPYKCKECGKAFHLPSELNNHQIVHTSNRPFECKVCGKSFKRESTLIQHSVIHGGVKSYECNECGKAFIHRSSLFHHRKIHSDEKPFKCQECGKAFVVLAYLTRHQSIHTGEKSFECQQCGSAFRYKSQLSKHQRSHTDVKLFQCMEGGNDFVHGTNLSIHQGIHTSENPFQCNEYGEAFKYHYQFPWTF---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A327-1", "uniprot_id": "D4A327_RAT", "id": "D4A327-1", "name": "", "aln": "MASSSSQHMACGSVTFRDVAVDFSQEEWACLDATQKVLYRDAMLETYSHLVTVVGSCLSKPHLITLLEQEKEPWMAVKEETDRPSPE--------------------------LETGYDAENISPENPINNGKFLKQSIKQLSRTFDFKDSSS-SNGPNYSAFHGLKDCQG-DADQQITNKEEMPPYTCQTLAHNIERAYECKECGKCLGCRSTLTQHQTIHTGEKPYECKECGKAFRLPQQLTRHQKFHSGEKPFKCNECGKAFHLPDLLKYHKTIHTGTKPFECRECGKAFNRVSNLVAHRIIHADVKPYECNECGKAFKRRSNLVQHQKIHSDERPFQCKDCGKGFIVLAQLTRHQNIHTGEKLFECHECGKAFRLPQQLTRHQKSHSGEKPFKCNECGKAFHLPDLLKYHKTIHTGTKPFECRECGKSFNRVSNLVEHRIIHADVKPYACNQCGKAFKRQKSLMQHQKIHSGERPFQCKDCGKAFIVLSHLTRHQTIHTGEKSFECNECGKKFRTATHLVMHQTIHTGEKPFECNVCGKAFRLQVYLSEHQKTHIEGKPFKCKLCGSAFRRKYQLNEHYTIHTDEKPYQCKECGKCFRQRSNFTEHQSIHTGNKPFECKECGKSFRLNTLLIRHQKSHSGERPYECKECGKAFHLPSELNNHQIVHTSKRPFECKVCGKSFKRESTLIQHGAVHAGVKSYECSECGKAFIHRSSLFHHRKIHSDEKPFKCQECGKAFVVLAYLTRHQSIHNGEKSFECQQCGSTFKYKSQLNKHQRSHTDVKLFQCMEGGNDFVPGTNLSIHQGIHSGENPFQCNEYGEAFKYHYQFPWTF---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0U1RQ84-1", "uniprot_id": "A0A0U1RQ84_MOUSE", "id": "A0A0U1RQ84-1", "name": "", "aln": "MASSSSQDMVCGSVTFRDVAVDFSQEEWAFLDATQKVLYRDMMLETYSNLVAVVGSCISKPDLIVLLEQEKEPWMAVKEETDWPSPD--------------------------LEADYDAENVFPENHSYNRNSPKQDIRQSSKTFDFRGSRF-SDGPKCSTFQGLQGCQEGDAGQQVTKKEGVPPYTCQTLAHSLQKPYECKQCGKCFNCSSTLSQHQSVHAGEKPYECKEYGKVFRLPQQLTRHQKSHSSEKPFECNECGKAFHLPHLLQNHKTTHTGTKAFECEECGKIFNRVSNLVAHRIIHADVKPYKCNECGKAFKRRSYYMQHQKIHSGERPFQCKECGKAFIFLAHLNGHQMIHTGEKSFACKECGKAFRLLQQLTRHQKFHSGDRPFKCNECGKAFPFPDRLKLHKTIHTNTKPFECRECGKSFKCVSHLAQHRIIHADVKPYECSECGKAFNRRSNLIQHQKIHSGEKPFECKDCGKAFTVLPQLTRHQRIHTGEKPFECKECGKKFYTGPHLAQHQRVHTGEKPFECNVCGKAFRLRACLSEHQKTHIEEKPFKCKLCGSAFRSRYQLSLHRQTHPHVRPFQCQECGKAYILLAQLIQHQTVHTG----------------------------ERSFECKECGKKFHTGSHLVQHQHFHTGEKPFECHVCGKAFR--------------------------------------------------------FQVYLSEHQKTHIEEKPFKCKVCGSVFRHRYQLSEHRLAHIDVRP---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LRD5-1", "uniprot_id": "A0ABK0LRD5_RAT", "id": "A0ABK0LRD5-1", "name": "", "aln": "MASSSSQHRACGSVTFRDVAIDFSKEEWACLDATQKVLYRDTMLETYRHLVSVVGRCISKPHLITLLEQEKEPWMAVNEETDRPSPAEGRQPKSQRVCRVEEAVRWSLTHQKGLETCFEAENVSPENHNYNIKSPKQTTQQLSKTLDAQGS-------HCSVFKGQRNCQEGDAAQKITNKKKLPTYTSQTLAHNMGKPYKCKDCGKCFGCKSNLIQHQSIHTGEKPYKCKECGKTFRLQQLLSRHQKSHSNERPFECDECGKGFHLSTLLKYHKNTHTGSKPFQCEECGKSFNRISTLFQHRTIHAGVKPYKCSVCGKAFNRRSNLMQHQKIHSGDKPFHCKECGKAFTVLAQLTRHQNIHSEDKSFECKQCGKIFSSGSYLLRHYDTHTSEKPFECNVCGKAFRLHLYLNEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDVKPYQCKDCGKFFRRRSNFTEHQSIHTGKKPFECKQCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNYHKASHTGQTPFHCEECGKSFKRVSSLVEHRIIHSGVKPYKCSECGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHTG----------------------------KKSFECDQCTSAFRLPYQLTQHQRIHYEVKPFQCKECGKGFVR--------------------------------------------------------STGLRIHERIHTGEKPFQCRECGEAFQYHYQFLGHFRIHVGKNPYECTECGKCFTYGRDLKIHQRTHTAEKS-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6R6-1", "uniprot_id": "Z780B_HUMAN", "id": "Q9Y6R6-1", "name": "Zinc finger protein 780B", "aln": "--------MVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLENYSHLIS-LGSSISKPDVITLLEQEKEPWIVVSKETSRWYPD--------------------------LESKYGPEKISPENDIFEINLPKHVIKQISKTLGLEAFYFRNDSEYRSRFEGRQGHQEGYINQKIISYEEMPAYTHASPIHNTHKPYECKECGKYFSCGSNLIQHQSIHTGEKPYKCKECGKAFQLHIQLTRHQKFHTGEKTFECKECGKAFNLPTQLNRHKNIHTVKKLFECKECGKSFNRSSNLTQHQSIHAGVKPYQCKECGKAFNRGSNLIQHQKIHSNEKPFVCRECEMAFRYHYQLIEHCRIHTGEKPFECKECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKECGKSFNRSSNLIQHQSIHADVKPYECKECGKGFNRGANLIQHQKIHSNEKPFVCRECEMAFRYHYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCGKAFNRGSNLVQHQSIHTGEKPYECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKFFRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKFHTGEKPFECKECGKAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYECKECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQLTEHYRIHTGEKPFECKECGKAFGLLTQLAQHQIIHTGEKPFKCKECGKAFNRGSNLVQPQSIHTGEKPYECKECGKAFRLHLQLSLHQKLVQVRNPLNVRNVGQPSDISSNLLNIRKFILG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 271, "similar_positions": 189, "identity": "31.22%" }, { "cls_id": "homologset.agr.HGNC:3311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFC2-1", "uniprot_id": "SP88E_DROME", "id": "Q9VFC2-1", "name": "Serine protease inhibitor 88Ea", "aln": "---------MHILSISLMAVLPAIALAGLCGVEPDAGLLDQRLNL------------------------YKGQQNFAVSMLNVIRQ------STPNENVFFSPYSTYHALLLAYFGS-SGDTE-KELAKVLHLDWADSKEVVRSAYILEKMNRKERQSKMPLEFSSADRIFFANDLHVT----ECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFN---SNSLEDVLSRLNADSLDDSLKQAMPR--EIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTS---ETIS--IGDSKHVAKIKVDEEGSTAAAATVLF-----TYRSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDPKTIKQ------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFC1-1", "uniprot_id": "Q9VFC1_DROME", "id": "Q9VFC1-1", "name": "", "aln": "---------MHTFSLVLLALLPVVTIAALD--KPELSFLNEFSQI------------------------FKGERDFSLALMKQIRE------IYPSGNLFFSPFSTYNALLLAYFSS-SEQTE-RELAQALNLGWALNKQQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVS----NKFNTLLYGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSN---KISLNRVISRLNADSVKKWFERALPQ--KIELSLPKFQFEQRLELTPILSLMGVNTMFTRN-ATFGDLTA---DPISLVIDDAQHLAKIKVDEVGSTAAAATILL-----VSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDPRQMQH------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4G075-1", "uniprot_id": "ILEUA_RAT", "id": "Q4G075-1", "name": "Leukocyte elastase inhibitor A", "aln": "-----------------------------------------MEQL------------------------SSANSLFALELFHTLSE------SSPTGNIFFSPFSISSALAMVFLGT-KGTTA-AQLSKTFHFDSVED-----VHSRFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEFLTSTQKMYGADLAPVDFQHASEDARKEINQWVKGQTEGKIPELLAVGVVDSMTKLVLVNAIYFKGMWEEKFMKQDTTDAPFRLNKKNTKSVKMMYQKKKFFFGYISDLKCKVLEMPYQ---------------GGELSMVILLPEDIEDESTGLKKIEEQITLEKLREWTKRENLENIDVHVKLPRFKIEESYILNSNLGRLGLQDLFNSSKADLSGMS----GSRDLFISKIVHKAFVEVNEEGTEAAAATAG------IATFCMLLPEEEFTADHPFIFFIRHNPTANVLFLGRVCSP-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D154-1", "uniprot_id": "ILEUA_MOUSE", "id": "Q9D154-1", "name": "Leukocyte elastase inhibitor A", "aln": "-----------------------------------------MEQL------------------------SSANTLFALELFQTLNE------SSPTGNIFFSPFSISSALAMVILGA-KGSTA-AQLSKTFHFDSVED-----IHSRFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDARKEINQWVKGQTEGKIPELLSVGVVDSMTKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKKDTKTVKMMYQKKKFPFGYISDLKCKVLEMPYQ---------------GGELSMVILLPKDIEDESTGLKKIEKQITLEKLLEWTKRENLEFIDVHVKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGMS----GSRDLFISKIVHKSFVEVNEEGTEAAAATGG------IATFCMLLPEEEFTVDHPFIFFIRHNPTSNVLFLGRVCSP-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8WGA3-1", "uniprot_id": "F8WGA3_RAT", "id": "F8WGA3-1", "name": "Leukocyte elastase inhibitor", "aln": "-----------------------------------------MEQL------------------------SSANSLFALELFHTLSE------SSPTGNIF-SPFSISSALAMVFLGA-KGSSAPSSLRLTFHFDSVED-----IHSRFQSLNAEMRKHGASHTLKVANRLYGEKTYNFLPEFLASTQKMYGADLAPVDFQHASEDARKEINKWVKGQTEGKIPELLAGGVVNSTTKLVLVNAIYFKGIWQEKFLTRHTTDAPFRLNKKDTKMVKMMYQKEKFPFGYIPDLKCKVLEMPYQ---------------GGELSMVILLPEDIEDESTGLQKIEEQLTLEKLYEWTKHENLKEIDVHVNLPKFKIEESYILNSNLGRLGLQDLFSSSKADLSGMS----ESRDIFISKIVHKSFVEVNEEGTEAAAATAG-------LVEYCLVSIEAFIVDHPFLFFIRHNPTANMLFFGRVCSP-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHP7-1", "uniprot_id": "ILEUB_MOUSE", "id": "Q8VHP7-1", "name": "Leukocyte elastase inhibitor B", "aln": "-----------------------------------------MEQL------------------------SSANTLFTLELFHTLKE------SSPTGNIFFSPFSISSSLAMVFLGA-KGSTA-AQLSKTLHFDSVED-----IHSCFQSLTAEVSKLGASHTLKLANRLYGEKTYNFLPEFLASTQKMYSADLAAVDFQHASEDARKEINQWVKGQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKKDTKTVKMMYQKKKFPFGYISDLKCKVLEMPYQ---------------GGELSMVILLPEDIEDESTGLKKIEEQLTLGKLHEWTKHENLRNIDVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLSGMS----GSRDLFVSKIVHKSFVDVNEQGTEAAAATGGII---QVLCEKMPTPQEVFTVDHPFLFFIRHNPTANMIFFGRVCSP-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SV42-1", "uniprot_id": "ILEUC_MOUSE", "id": "Q5SV42-1", "name": "Leukocyte elastase inhibitor C", "aln": "-----------------------------------------MGQL------------------------SSANNLFALELFHTLNE------SNPTGNTIFSPVSISSALAMVYLGA-RGSTA-AQLSKTLHFDSAED-----IHSQFQSLTAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASIQKTYSADLALVDFQHASEDARKEINQWVKGQTEEKIQELFAVGVVDSMTKLVLVNATYFKGMWQKKFMARDTTDAPFRLSKKVTKTVKMMYLKNNLPFGYIPDLKCKVLEMPYQ---------------GGELSMVILLPEDIEDETTGLEEIEKQLTLEKLQEC---ENLQNIDVCVKLPKFKMEESYILNSNLGQLGVQDLFSSSKADLSGMS----GSRDLFISKIVHKSYVEVNEEGTETDAAMPG------TVVGCCLMPME-FTVDHPFLFFIRHNPTAHVLFLGRVCSP-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30740-1", "uniprot_id": "ILEU_HUMAN", "id": "P30740-1", "name": "Leukocyte elastase inhibitor", "aln": "-----------------------------------------MEQL------------------------SSANTRFALDLFLALSE------NNPAGNIFISPFSISSAMAMVFLGT-RGNTA-AQLSKTFHFNTVEE-----VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQ---------------GEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMS----GARDIFISKIVHKSFVEVNEEGTEAAAATAG------IATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z6R4-1", "uniprot_id": "A1Z6R4_DROME", "id": "A1Z6R4-1", "name": "", "aln": "-----------------------------------------MSEP------------------------QEGRNQFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGA-SGSTA-EELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDRGP--VLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFAD-SEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYD---------------YSNIHMLILLPNEVN----GLQELEQQLNTVDLADIDAALTLQ--DVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDK-AKLDGLFT---SQSGQKISAARHRGYIDVNEAGSEAAAVSFMK-----IVPMMLNMNKKLFKADHPFVFYIRN--PQAVFFAGRFSNPKSGSGSGEEGLSREGFDANMYNV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3N1-1", "uniprot_id": "SP27A_DROME", "id": "Q9V3N1-1", "name": "Serine protease inhibitor 27A", "aln": "MTKMGGNLAVMLLSLFLSALATGNGNSIPTTTTPQGVFETRTDKLPGGAASVPSGAGIYDDIDTFVPFRSDSHDPFSWHLLKTVLQN-----ETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANTQTDIRSQNN---VREFYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTN-PEAAADAINAWAANITQGRLQQLVAPDNVR-SSVMLLTNLIYFNGLWRRQFAT--TFQGSFFRSKDDQSRAEFMEQTDYFYYTTSEKLKAQILRLPYK----------------GKNSLFVLLPYALN----GIHDLVKNLENDELKSA--QWAMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIFEDS-ASLPGLTRGADVAGKVKVSNILQKAGINVNEKGTEAYAATVVE----IENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSPTTQN-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLV3-1", "uniprot_id": "Q9VLV3_DROME", "id": "Q9VLV3-1", "name": "", "aln": "-----------------------------MQGNNKIKYLVLLLIA------------------------TSVLGKFKLNLLELVMD-------KAESNFIASPLCIEIGISMILMGA-KGTTA-EELRSVLDLPVDVT-------EMAKKYERIMSNFQKHNGLRFTNWLYVNETYEVRQDYNTLMKSTFMAEGKDP---LSQRKASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMSHVG--RFRIADHSYGQIIEMPFD---------------NSDLSMIIGLPLHNT-YLSSIEKILRTLSESLVENN----------VHVELPKFKIKYQTELVESLKKLGIHLIFSNT-SDLSGLLT---NGTGAKINHVVHKSFIEINERGASTGEASDHA-----ESIQKKTRASTSFKVNRPFVFLIRD--KHTVYFRGRVVRLPNELHL-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL44-1", "uniprot_id": "Q9VL44_DROME", "id": "Q9VL44-1", "name": "", "aln": "--------------------------------------MSEAANP------------------------TPYDCHIGAGIYHSIAT------SFAEQNVVVSPLLLEATLSLLFLGS-DGATA-EELQKQLRLKQRFASN--AKMANFYAAELGNITTDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLLAAN-LQSKWFLPFSAYRTGLYEFHSGSQVKSVPMLFDDDMFVKFAELRDLDARAIELPYEH--------------AEELSMLLILPNQRG----GLQELEKQLHDLDLGALQQRMQMEG--VQVLLPKFSIDFECSLRQPLKQLGFEEIFAAS-ANFKHLH----ASANLPIADVLQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAIRS--ENVTYLMGHVVEF-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . * . ** : : .: .* : : . . . : :* .. * * * * . :: : :.:*: . :.: ** .:. : : : : : **:: :. * * :*. :* : : : : : :.::* *: : * ::**.* * : * ", "identical_positions": 26, "similar_positions": 61, "identity": "5.15%" }, { "cls_id": "homologset.agr.HGNC:33110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZMW2-1", "uniprot_id": "ZN782_HUMAN", "id": "Q6ZMW2-1", "name": "Zinc finger protein 782", "aln": "MNTFQAS---------------VSFQDVTVEFSQEEWQHMGPVERTLYRDVMLENYSHLVSVGYCFTKPELIFTLEQG-----------------------------------------------------------EDPWLLEKEK----------GFLSRNSPEDS------QPDEIS----------EKSPENQGKHLLQVLFTN-----------------KLLTTEQEISGKPHN--------RDINIFRARMMP---------------CKCDIAGSACQG---------------------LSLMAPHCQYSKEKAHERNVCDKWLISIK----DGRTNTQEKSFAYSKIVKTLHHKEEVIQHQTIQTLGQDFEYNESRKAFLEKAALVTSNSTHPKGKSYNFNKFGENKYDKSTFIIPQNMNPEKSHYEFNDTGNCFCRITHKTLTG--------------GKSFSQKSHIREHHRVHIG---VKPFEYGKSFNRNSTLPVHQRTHATDKYSDYHPCTETFSYQSTFSVHQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKPYECPECGKAFSEKSRLRKHQRTHTGEKPYKCDGCDKAFSAKSGLRIHQRTHTGEKPFECHECGKSFNYKSILIVHQRTHTGEKPFECNECGKSFSHMSGLRNHRRTHTGERPYKCDECGKAFKLKSGLRKHHRTHTGEKPYKCNQCGKAFGQKSQLRGHHRIHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTGEKPYQCEECGKTFRQKSNLRGHQRTHTGEKPYECNECGKAFSEKSVLRKHQRTHTGEKPYNCNQCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSSLREHQKAHPGD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RCK0-1", "uniprot_id": "M0RCK0_RAT", "id": "M0RCK0-1", "name": "", "aln": "MNLSQKPQRVHPQEQDGSCERLVSFEDVTVDFSQEEWRRLDPAQRRLYQEVMLEIYSHLLSVGYPIPSPGAIFRIKKRKKTQTGEAKFPHHQCWCQEVESEFYTPRQKASENAAFQTRKASALSGHGLWCSILEVLWQDPDLTKRDGQSQIPPWSPGAFLNKKTQNTDRDCGCKEPGKTTPLVSNLISTQKGAPKSLAKHLKRNLEANGEEQGNVTKQLNDIVTLGRLCTQDTNCTVPHEGPCEGDQCRKVPIHKQPLAEKEVHSHEKPDEGTGRGRTDDASAFCQHQTAHTGEGPLVCHKCEEVFLQKTEFASHQETHPEKPYECPDCGKSFSRTSNLQVHHRIHTGEKPYECRDCGKSFNNTSQLKVHYRIHTGERPYVCPVCGKAFKQKSILSTHETIHTGEKPYKCTVCGKLFSCTSRLKVHYQIHMKEKPYECGDCGKAFKRKSSLTVHQKIHSRQTRHACSECGKEFSQKSELSTHQRLHLGKNSHKCADCGKAFTYASQLKMHHRVHTGEKPYKCRDCGKSFTYSFTLNVHRRIHKVEKPHKCSVCGKALASKYQLEEHERIHTGEKPYVCTECGKGFHGRSGFLRHQITHTRDKPFVCHKCGKAFFQRSQLTSHQQTHTGEKPYPCRYCGKSFSHTSQLTVHHRIHTGERPYKCNYCGKSFSNSSQLKEHLRIHTGETPYACSECGKAFSRRSSLNLHTKIHTGEKHHICSECGKAFSQKSVLRTHQRIHTGEKPYKCGDCGKALASKGQLRDHQRIHTGEKPYVCPECGKGFFGRSSLHRHQMTHTKERPFVCQKCGKTFIQKSALTSHQQIHTGEKPYVCPECGKGFYNKSSLPRHQMTHTKGRSFVCQKCGKAFLQKSVLKCHQRTHTCKKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VGR8-1", "uniprot_id": "Q9VGR8_DROME", "id": "Q9VGR8-1", "name": "", "aln": "MRCAVPN--------------CRNFSDCRSKRNAAQQQRLGFFRFPKCPDTFKAWLAFCGYTEESLKLKNPCICIEHFK----------------------------------------------------------------------------------DEDIEGS------------------------LKFEMGLAKKRTLRPG-----------------AVPCVNKSQESGSDR-------ARKERSQRRRNQE-----------------------------------------------LVAELLAEEEAKLIHPEATSFEQDSVYLSETVTMELDPLSGEEKLEELQKCRTCYN--DFTADFRAKDLFDPANSVLLFHIEVISGVWISHKPDEPRLMCPACKSALDQAIDFREMCISTELKLSQAKPSTDEVQIEAENENPISSDH---------------DLISDTENTNVEEIEDAG---------GDHVEDEATSDDQTSQEAVDEVAESPAAQDPLSVALGAKIFKELLDQYTGKEKARLRKGAPIASKPKAKEKAAGEQKPKRS--ANPKTKEERNLIRRAQLRAKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRNMHIRIR---------------------------HRGETPFACGFCSETFAYPGARQKHESEVHNAAPRLIVKR---INPKPMPKPRESVR-----YQCKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTHEK-RPLQCDVCLKGFYQRTRLREHELIHTGERPYWCEVCNVNFRYKYNMKSHANSKMHQDNARKLGVVQIVATE---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .*.* . . : :::. . :.: :. . : : ::: : : . . . : * .. .:. ... *. : : : .. : :. . . . . : *: . :: : :. . : : .. : :. .. . . : : ::: .: . .: . . : . :*:... .. . * *. . : : .: :: . . ..:: .:.:.: . : *. . : :: :** . .. . : :: :: : *. *.:** * * ** * : * * *:* :* * : * ** *: *. *.::* .. . * . : :. *. : :. :: *:* * : :.* * * : **. :.* * .*.* : ..*: *: ** :* *: * * * ::: * .*: ****:** * *. * * .: * :: : . : ", "identical_positions": 70, "similar_positions": 185, "identity": "7.93%" }, { "cls_id": "homologset.agr.HGNC:33111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0V8-1", "uniprot_id": "D4A0V8_RAT", "id": "D4A0V8-1", "name": "Zinc finger protein 784", "aln": "--------------------------VLVPDGGRPATPPGDLIEIQVVKVTDTTSAPEPPEPGSFHCALCPAAFRLVSELLFHEHGHLAGLEGLGQGGDPSRCHVCGHSCPGPASLRAHYSLHTGERPYRCPLCPRAFKALAPLLRHQHRHGVEPGTPGRLLPTAAAGQPNSRVAQERSEVVMTAAAAGAVVGKPFACRFCAKPFRRSSDMRDHERVHTGERPYHCGICGKGFTQSSVLSGHARIHTGERPFRCMLCDRTFNNSSNFRKHQRTHFHGPGPGVGESGGQLRSSSVSQESRSKCGTENTMEEGCRETKKVNVEVDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCA9-1", "uniprot_id": "ZN784_HUMAN", "id": "Q8NCA9-1", "name": "Zinc finger protein 784", "aln": "MAAARPEAQSRSSPTPESRSQEPLDLVLVPDDCRPGTPPSDLIEIQVVKVTDTTLVPEPPEPGSFHCALCPAAFRLVSELLFHEHGHLAGAEGGGQGGDPSRCHVCGHSCPGPASLRAHYSLHTGERPYRCALCPRAFKALAPLLRHQHRHGVEPGTSRRPPDTAAVAEQRPGVAPERAEVVMAAAAAGAAVGKPFACRFCAKPFRRSSDMRDHERVHTGERPYHCGICGKGFTQSSVLSGHARIHTGERPFRCTLCDRTFNNSSNFRKHQRTHFHGPGPGLGDSGGQLG-SSAAEGSGSGCGVGDPAEEGRGETAKVKVEADQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BI69-1", "uniprot_id": "ZN784_MOUSE", "id": "Q8BI69-1", "name": "Zinc finger protein 784", "aln": "MAAARPDPPIPSSPTRESPSPEPPDLVLVPDG-RPVTPPGDLIEIQVVKVTDTTSVPEPPEPGSFHCALCPAAFRLVSELLFHEHGHLASMEGLGQDGDPSRCHVCGHSCPGPASLRAHYSLHTGERPYRCSLCPRAFKALAPLLRHQHRHGVEPGTSERLLPTTTTGQPNSRVAQERSEVVMAAAAAGAVVGKPFACRFCAKPFRRSSDMRDHERVHTGERPYHCSICGKGFTQSSVLSGHARIHTGERPFRCMLCDRTFNNSSNFRKHQRTHFHGPGSGVGESRGQLRSSSVSQES--------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****. ** ***.************** .*********************************. ** **.**********************************.*************************. * *::..: .. ** **:****:******.***********************************.*************************** ************************.*:*:* *** **.:: * ", "identical_positions": 231, "similar_positions": 24, "identity": "71.3%" }, { "cls_id": "homologset.agr.HGNC:33112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGD4-1", "uniprot_id": "A0A8I6AGD4_RAT", "id": "A0A8I6AGD4-1", "name": "", "aln": "--------------------MDALTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNWEDQ------------CIEEHCQSFRRHGSMCGSVRAPSETRSVWSPGAGVRSSCEPSNLDAGNQALVLFNGSLCS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1M5V3-1", "uniprot_id": "F1M5V3_RAT", "id": "F1M5V3-1", "name": "", "aln": "--------------------MDALTYDDVHVNFTREEWALLDPSQKSLYKDVMQETYRNLTAIGYNCEDH------------SIEEHCQSFRRHGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LX67-1", "uniprot_id": "F1LX67_RAT", "id": "F1LX67-1", "name": "", "aln": "MARIFS-----------LLTKKAVTYEDVHINFTREEWALLDPSQKSLYKDVMLETYGNLTAVGYYWEDH------------GIEEYCQNFRRNGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQV5-1", "uniprot_id": "ZN788_HUMAN", "id": "Q6ZQV5-1", "name": "Putative KRAB domain-containing protein ZNF788", "aln": "MRNMIPQDNENPPQQGEANQNDSVAFEDVAVNFTPDEWALLDPSQKNLYREVMQETLRNLASIEVLWKRD------------SLKVKVISMEKF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPB3-1", "uniprot_id": "Q7TPB3_RAT", "id": "Q7TPB3-1", "name": "", "aln": "MH--------------RKQEMEPVTFEDVAVNFTLGEWTMLDSSQKKLYRDVMKETFMNLISIGKTEEEDNEEYQNPKGSLRTLMVERLCKYHHGNQYGETQRQSPDHVVSEKMPPAVSECERDILIHLPSDMHFKGQTGEKPCQYQEQMEKTLKHKKCWKDFSYSELLWMHKNPPMKQKPHENKEANEASRSFTSDHDYEGTFTEEKSYICKQCGKAWSDSCSLLWHERSHIQEKRHTCKQCGKAFSRPSQLHKHERIHTGEKPYVCTHCGKAFIDRRTCHNHERTHTGVKPFACKQCGKAFLRSCQLLIHERIHTGERPFVCKHCGKAFTYSSACYYHERIHTGEKPCVCKQCGKAFKCSAYLHIHERSHSGEKPYVCKHCGKAFAYATGCHKHERIHTGEKPYMCVQCGKLFTFPRSLHIHERSHSGEKPYVCKQCGKSFTQGTSLRRHERIHTGEKPYVCRQCGKAFIQRDDCYSHERTHTGEKPFMCVQCGKTFTFSKSLQIHEKNHTGEKPYICKQCGKAFTCSTYLLRHERTHSEKKLSG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..::::** :*** **::**.***.**::** ** ** :: : . : : ", "identical_positions": 20, "similar_positions": 19, "identity": "3.66%" }, { "cls_id": "homologset.agr.HGNC:33113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8MUP2-1", "uniprot_id": "CSKMT_HUMAN", "id": "A8MUP2-1", "name": "Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial", "aln": "MAALRRMLHLPSLMMGT--CRPFAGSLADSCLA---DRCLWDRLHAQP-RLGTVPTFDWFFGYDEVQGLLLPLLQEAQAAS--PLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAVARG--GLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGSYGWTVT----VQELGPFRGITYFAYLIQG---SH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q501S4-1", "uniprot_id": "CSKMT_DANRE", "id": "Q501S4-1", "name": "Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial", "aln": "MLLNRFLVPLRSLQKLTQARRWHQTSLINDLVVNMDKKAMWDRFYTENGSKGQFKNFEWFFGFPSVKDLVLPALQAMSCSHSGPLHILDMGCGTSALGPCIYSTSPCAVRVTCADISPVAVK----LMEEHTKSTSTQPCNPSSALVFLELDCTQMTGHFKSRSLDLILDKGTTDALVRSKEGQVKAGQILRQSLQVLRPSGSFLQFSDEDPDARLIWLEREVQGAEVTADVGVQEIGELRGVSYFCYQISPRSRPHS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :: * ** * * . ** :. :. .:.:***:::: * . .*:****: .*:.*:** ** ..: **::**:*****:* . :*:.** .* * .*:***** *:* . .*. * :*:*:* *:. *. :: . .* *::*:***** **:.*. * :* *:* :.*:**.*.*:::********.** **: * ** ***:* :**::**.* *. .* ", "identical_positions": 100, "similar_positions": 76, "identity": "38.76%" }, { "cls_id": "homologset.agr.HGNC:33114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8J5-1", "uniprot_id": "D4A8J5_RAT", "id": "D4A8J5-1", "name": "", "aln": "MAHVMTFRDVAVDFSPEEWACLSLEQRSLYRDVMLENYSHLVSVGLCIYQPHVFPVLEKEQDACVDLSNETSRFLPDTDSGWQMKKVLPKNSIFGSRLSRWEVMRMERNQGLEGSSPGVDWEDKGQDQSQNENQEERLKQMTLTCDKLPLLNLLTAFNQCPRLNTAEKAKEFKSE-KSFSFAPEPSQLQLIHTDAKFREDKSCGKTFPPGPKLPRYRAVPAGKKAFQCEECGKAFSFRSSLTGHKRIHTGEKPFKCKECGKAFRFHSLLSVHVRTHTGEKSYECKECGKYFNYSSDLTRHHRIHTGEKPYQCRECGKAFSCGSDLTRHQRIHTGEKPYECHECGKAFIQQSHLIKHQRIHTGEKPYVCKECGKAFTCGSQLSQHRKIHTGDKFHKCKECKNSFSFALDHTQRQLIYIGEKFFEDKENGKAFFPDAEFPQYDTAPSGKKLYECKECGKAFSLRAIVSSLKKIHNREKLFKCKDCEKAFRCPSDLSRHQKIHTGEKPYKCKECGKGFICRSDLGRHQRVHTGVKPYECKECGKAFTRGAHLTQHQKIHSKKSHDFNEGEKAFGSGSDHTPGSLIDTGEKCWEGKEYGETVLHDPERTQPQTAKTTYDCKEKGKDFSWRSRDTDLKTVHIREKRFQCKECPKAFRYSSELTRHQRLHTGEKPYKCQECWKAFASASDLARHQRIHTGERPYECNECGKAFIQQSHLIKHQRVHNVEQPKDVMSAEKSSPGSQMLLNMREFTLVNNLINLRSVGKILLMAQLSQCPKVYTDEKLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PG37-1", "uniprot_id": "ZN790_HUMAN", "id": "Q6PG37-1", "name": "Zinc finger protein 790", "aln": "MAHLMMFRDVAVDFSQEEWECLDLEQRDLYRDVMLENYSNMVSLGFCIYQPEAFSLLEKGKEPWKILRDETRGPCPDMQSRCQTKKLLPKNGIFEREIAQLEIMRICKNHSLDCLCFRGDWEGNTQFQTLQDNQEECFKQVIRTCEKRPTFNQHTVFNLHQRLNTGDKLNEFKELGKAFISGSDHTQHQLIHTSEKFCGDKECGNTFLPDSEVIQYQTVHTVKKTYECKECGKSFSLRSSLTGHKRIHTGEKPFKCKDCGKAFRFHSQLSVHKRIHTGEKSYECKECGKAFSCGSDLTRHQRIHTGEKPYECNECRKAFSQRSHLIKHQRIHTGEKPYECKECGKAFTRGSHLTQHQRIHTGEKSHECKECGKAFIRGSNLAQHQNVHVGRKPYKCEKCG----------------------------KAYIWSSHLARHQRIHTGRKPYECKQCGKTFTWASYLAQHEKIHNERKSYECKECGKTFLHGSEFNRHQKIHTGERNYECKECGKTFFRGSELNRHQKIHTGKRPYECEECGKAFLWGSQLTRHQRMHTG--------------------------------------------------------------------------------EEPYVCKECGKSFIWGSQLTRHKKIHTDAEPYGCKKSSHIFSHHSYFT-EQKIHNSANLCEWTDYGNTFSHESNFAQHQNIYTFEKSYEFKDFEKAFSSSSHFISLL------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:* ********* *** **.****.***********::**:*:*****..*.:*** ::. * :** ** :* * **:****.** .::: *:**: :*:.*: . ***.: * *: ::**** :**: **:* * :* *.** ****.:* :***. *:* ..: :* *****. ** **.**:** *..:: :*::* : **:::*:****:**:********************:********* **** * ************** *. .******:*********:*.** **** *.* :*************:****** : *** :*********.: ******** **:*:**:::*.* * :**::* **:: .:.:.::: :*:* ****:***:*: : ::. :****..* ::**:* *:* *::.*********: *:****** *: *:*.***::*** :****:****** *::**:**::*: *: : **** *:* :.*:****:::**. :** *::. : *: * :: .*:**.. . * .: *::* ::*:: :**.::..*:. :. . **: ..*. ::.: ", "identical_positions": 339, "similar_positions": 181, "identity": "43.41%" }, { "cls_id": "homologset.agr.HGNC:33116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFP7-1", "uniprot_id": "D3ZFP7_RAT", "id": "D3ZFP7-1", "name": "Protein inscuteable homolog", "aln": "------------------------------MRRPPGDGDSTGEGPGNWGLWG----------AQESRRLCCVGPDRCG------------------------------------QALLQIGMNMMALP------------------------------------GGRHLGSIPLQEQR------LHFMQVDSVQRWMED-----LKLMTECECMCVLQAKPISLEEDTQSDLILAGGPGP-----------------------------------GDPLQLLLKRGWVISTELRRIGQKLAQ---------------DRWAR----------------------------------VHSMSVRLTCHARSMVSEYSTISRTTSQEMGQAEKLLMEKCSELSAVTER---------CLQVENEHVLKSMKACVSET------------------LSMLGQHFGQLLELALTREVQALVRKIDTSDNIYITES---TTGNLFSLTQEG-APLCRIIAKEGGVVALFKVCRQDTFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLTDILTDDSHS---EATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLASAALANITFFEKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRS--GTPAEVAACERVQQKAAVTLARLCRD--------------PDVAREAVRLSCMSR-------------LIELCRSPSERNSSDAVLVACLAALR-----------RLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3HNM7-1", "uniprot_id": "INSC_MOUSE", "id": "Q3HNM7-1", "name": "Protein inscuteable homolog", "aln": "------------------------------MRRPPGDGDSTGEGPGNWGLWG----------AQESRRLCCVGPDRCG------------------------------------QALLQIGINMMALP------------------------------------GGRHLDSVPLQEQR------LHFMQVDSVQRWMED-----LKLMTECECMCVLQAKPISLEEDTQGDLILAGGPGP-----------------------------------GDPLQLLLKRGWVISTELRRIGQKLAQ---------------DRWAR----------------------------------VHSMSVRLTCHARSMVSEYSTISRTASQEMGQAEKLLMEKCSELSAVTER---------CLQVENEHVLKSMKACVSET------------------LSLLGEHFGQLLELALTREVQALVRKIDTSDNIYITES---TTGNLFGLTQEG-APLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLADILTDESHS---EATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLASAALANITFFDKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQCGSDIIQENGVQLIMGMLSEKPRS--GTPAEVAACERVQQKAAVTLARLCRD--------------PDVAQEAVRLSCMSR-------------LIELCRSPSERNSSDAVLVACLAALR-----------RLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1MX18-1", "uniprot_id": "INSC_HUMAN", "id": "Q1MX18-1", "name": "Protein inscuteable homolog", "aln": "------------------------------MRRPPGNGEAASEGPGGWGLWG----------VQESRRLCCAGHDRCK------------------------------------QALLQIGINMMALP------------------------------------GGRHLDSVTLPGQR------LHLMQVDSVQRWMED-----LKLMTECECMCVLQAKPISLEEDAQGDLILAGGPGP-----------------------------------GDPLQLLLKRGWVISTELRRIGQKLAQ---------------DRWAR----------------------------------VHSMSVRLTCHARSMVSEYSAVSRNSLKEMGEIEKLLMEKCSELSAVTER---------CLQVENEHVLKSMKACVSET------------------LSMLGQHFGQLLELALTREVQALVRKIDASDNIYTTES---TTGNLFSLTQEG-APLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEKVDGVLCLADILTDNSHS---EATRAEAAAVVAQVTSPHLPVTQHLSSFLESMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAIRVLLEACSDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRS--GTPAEVAACERVQQKAAVTLARLSRD--------------PDVAREAVRLSCMSR-------------LIELCRSPSERNSSDAVLVACLAALR-----------RLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2R4-1", "uniprot_id": "Q9W2R4_DROME", "id": "Q9W2R4-1", "name": "", "aln": "MSFQRSYSKVWWGSEQSSLTSGGFYSSFSGGSSTSSTSNYPQRQPASLGPLGNLSCIQEVEDEQNSSKLSWHKHDSPGSLRSQDSGFSDNEESHQLQHQQNLSPPSPQSDKQQTPAATPTSVHSVATPPTVVRRVGNSSFYSPLISVTRRISFTSGQITPKTRSGDEDAEDAELEASRSRLFEQLDSMKLDDGEAEAEEDSPPRPAIRRRRRLMRKPMPEPEAASASEEEEVVIAPPPPPPYNNETVYLGEAPPPYNNETVTFGATEQDESLQQQPSPLRVRSLR-FTASTSTPKSGSKIAKRGKKHPEPVASWMSEQRWAGEPEVMCTLQHKSIAQEAYKNYTITTSAVCKLVRQLQQQALSLQVHFERSERVLSGLQASSLPEALAGATQLLSHLDDFTATLERRGVFFNDAKIERRRYEQHLEQIRTVSKDTRYSLERQHYINLESLLDDVQLLKRHTLITLRLIFERLVRVLVISIEQSQCDLLLRANINMVATLMNIDYDGFASLSDAFVQNEAVRTLLVVVLDHKQSSVRALALRALATLCCAPQAINQLGSCGGIEIVRDILQVESAGERGAIERREAVSLLAQITAAWHGSEHRVPGLRDCAESLVAGLAALLQPECCTQTLLLCAAALNNLSRMEATSHYSIMSNEAIFRLIDTLEHQTCGTSVFLYEQIVGMLHNMSLNKKCHSHLANGVIINFITSVYQTEFYQTYGSRAESDAQRRTIKTILHTLTRLASDSPTLGAELLEQWHLPDLLRQSLALKPANSQQQQHLDSSYGGDISQLARQLLRAHGQEQQLLQATPAPGGSFSSGHQTPEAQTQTNSSGMSSSGSKTKAKSSASPLLKFNLTRQESFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... .: . . *.. * * *:* :*. * * .:: :* * *... . * .* *. *::*. : *: : . . * .:* : . . : ::::* * * .**:: * :. **. : *.*:*: :*** ::. :: * * . * :. .: * . *:.: .:::*. ** : . *: *:.::: .:* :.:* .* *.* : * *:.** .*: *: .: ...*:.: :* *.*. :.:: .* :*: * :.. .: . ***:**::**. :.::** . .*: : *** :* . * **.:::**:*:. :::..: : *.:*:.* * * .. :.:**.:*** *:: :: : ::. :** *::: .: : : :*** :* ***: ::* *.: : :::* .: . : . *: ** * .*. :. **:**. * **: :::: *. . : :*.*. . :..: *: . .* : . ..*:..*. : .:. : : . :****", "identical_positions": 128, "similar_positions": 228, "identity": "14.88%" }, { "cls_id": "homologset.agr.HGNC:3312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF91-1", "uniprot_id": "ELAV1_RAT", "id": "B5DF91-1", "name": "ELAV-like protein 1", "aln": "--------------------------------------MSNGYEDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70372-1", "uniprot_id": "ELAV1_MOUSE", "id": "P70372-1", "name": "ELAV-like protein 1", "aln": "--------------------------------------MSNGYEDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15717-1", "uniprot_id": "ELAV1_HUMAN", "id": "Q15717-1", "name": "ELAV-like protein 1", "aln": "--------------------------------------MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QTX4-1", "uniprot_id": "A0A2R8QTX4_DANRE", "id": "A0A2R8QTX4-1", "name": "ELAV-like protein", "aln": "MAVRRGHIRYLKVCEVQNQGNDRDSHKGASSIKQEVYDMPNGYEDPMGDEPSD--AKTNLIINYLPQNMSQEELRSLFSSIGEVESAKLIRDKMAGHSLGYGFVNYVNPSDAERAINTLNGLRLQSKTIKVSYARPSSDGIKDANLYISGLPKTMTQKNVEDMFTQYGRIINSRILVDQASGLSRGVAFIRFDKRSEAEEAIKDLNGSKPSGASEPITVKFAANPNQSKNSQLLSQLYHTQSRRFGGPVHHQPQRFRFSPMSVDHS--VSSMNVASSSSSGWCIFVYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTSKCKGFGFVTMTNYEEAAMAISSLNGYRLGDKVLQVSFKSSKSHK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.***** *.:: . .:****:*******:*:*********************:*************...******.*********************: ************:*****:*****:::*******:****::*********************..:** **.*:**************.** *******: :**********.********.*** :*.:**...:*******:*********************************.********************:**********:******:.****", "identical_positions": 266, "similar_positions": 47, "identity": "73.08%" }, { "cls_id": "homologset.agr.HGNC:33125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99NI3-1", "uniprot_id": "GT2D2_MOUSE", "id": "Q99NI3-1", "name": "General transcription factor II-I repeat domain-containing protein 2", "aln": "MAQVAVTTQPT-DEPSD-GRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVYVVGTERGCAFVNARQDLQKDFAQHCQGEGLPEEKPLCLGNGEACP-GEAQLLRRAVQDHFCLCYRKALGTTAMVPVPYEQMLQDEAAVVVRGLPEGLAFQHPDNYSLATLKWILENKAGISFAVKRPFLGAESQLGGLGMVTDAGRPTVPPNDSYGPVSVKTEPMEDSGTSPRAAAMLIKTESEDPNYNVCNVQGSQHFSASSDVTGMELPSEESTRMVALET-NEDPETEVKMEGNASPSNLVNSAAGVEDLRIIQVTVADNEKERLSGLEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILDAADFIKFTVIRPLPGLELSN----------------VGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSVSVSKEYNLRRHYQTNHSRHYDQYSGQAREEKLRELKRGLRKYLLGASEIVCPEQP--FPNASPPTNSAVQPAEEVAGSLWEKLRQKIRSFVAYSIAIDEITDINDTTQLAIFIRGVDDNFDVSEELLDTVPMTGAKSGNEIFLRVEKSLKKFSIDWSKLVSVASTGTPAMMDANSGLVTKLRARAASCCKGADLKSVRCIIHPEWLCAQKLRMGHVMDVVVDSVNWICSRGLNHGDFTTLLYELDSQYGSLLYHTALKWLGRGLVLRRFFESLEEIDSFMSSRGKPVPQLSSRDWILDLAFLVDMTTHLNTLDASLQGHSQIVTQMYDFIRAFLAKLCLWETHLARNNLAHFPTLKSVSRSESDGLNYIPKIVELKAEFQRRLSDFKSCESELTLFSSPFSTTIDSVREELQMEVIDLQCNTVLRTKYDKVGVPDFYKHLWSSYPKYRSHCARMLSMFSSTHICEQLFSILKLSK-------KEAQWGAALQVAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZN25-1", "uniprot_id": "A0A8I5ZN25_RAT", "id": "A0A8I5ZN25-1", "name": "", "aln": "MAQVAVSTQPMGNESSD-GRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVYVVGTERGCAFVNARQDLQKDFAQHCQGEGLPEEKPLCLENGAACP-GEAQLLRRAVQDHFCLCYRKALGTTAMVPVPYEQMLQDEAAVVVQGLPEGLVFQHPDNYSLATLKWILENRAGISFVVKRPFLGAESQLGGLGTVTDAERPAAPPNDSYGPVSVKTEPMEDSGTSPMAAAVLIKTESEDPNFSPCNAQGSQHPSASSEVIEMELPSAGSTPVVSSET-NEDAEAEVKMEGNANPSSTVNSAAGVEDLKIIQVTVPDNEEERLSGLEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILDAADFIKFTVIRPLPGLELSNGQAIGSCQITIPCLYKVGKRKIDQEGRVFQEKWERAYFFVEVQNVPTCLICKQSVSVSKEYNLRRHYQTNHSRHYDQYSGQAREEKLRELKRGLRKYLLGASEIVCPEPT--LSNASPPTNSVVQPVEDVAGSLWEKLRQKIRSFVAYSIAIDEITDINDTTQLAIFIRGVDDNFDVSEELLDTVPMTGAKSGNEIFLRVEKSLKKFSIDWSKLVSVASTGTPAMMDANSGLVTKLRARAALCCKGADLKSVRCIIHPEWLCAQNLKMGHVMDVVVDSVNWICSRGLNHSDFTTLLYELDSQYGSLLYHTALKWLGRGLVLRRFFESLEEIDSFMSSRGKPVPQLSSRDWILDLAFLVDMTTHLNTLDASLQGHSQIVTQMYDFIRAFLAKLCLWETHLARNNLAHFPTLKSVSRSESDGLNYIPKIVELKAEFQKRLSDFKSWESELTLFSSPFSTKIDSVREELQMEVIDLQCNTVLRTKFDKVGVPDFYKHLWSSYPKYRSHCAKMLSMFSSTHICEQLFSIMKLSK-------KEAQWGSALQAAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6EKJ0-1", "uniprot_id": "GTD2B_HUMAN", "id": "Q6EKJ0-1", "name": "General transcription factor II-I repeat domain-containing protein 2B", "aln": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSN----------------VGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:* * :*.*. *******:***************************:************** *:*****::* .*** * ** * ** **:::**:**:*:**:** ******.*******:**:*::****:*****:.****:**.**********:***** ::*****.****** * **** *. ..*.:* **:.********** * * *: :*.******: * ***: *:*.:* **** ** :*. * ***.*:***:***:..*. .*********.*:****.***:****.:********************************************************************:**:***************** ****************************:*********:*****************:*****: : *:***:***:********:*: *** :.*.**. :* ***.*::**.******:*******************:************:****************:*****************.*:**:************:***.******::*.* ****:***: ****** ****:*:*.*******.************.:*****************:* :***.*****:*******************:***** *** ********* ***:*: **************:***************:*********** ***.***********.***:***:****** *************.****:****************:**:****:*:***:**.*****: ***::****.**:********:**** *::**.:.*: **", "identical_positions": 737, "similar_positions": 136, "identity": "76.37%" }, { "cls_id": "homologset.agr.HGNC:33128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYR7-1", "uniprot_id": "ACOT3_MOUSE", "id": "Q9QYR7-1", "name": "Acyl-coenzyme A thioesterase 3", "aln": "------------MHAFTTQNPNRMAPTVILEPAGGCLCDQPVHIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGIGSGLLEYRASLLAGKGFAVMALAYNNYEDLPKDMDIIHLEYFEEAVTYLLSHPQVTGSGVGVLGISKGGELGFAMASFLKNITAAVIINGSISNIGGNLQYKDETVPSVGINTKRVKRTKDGLKDIVDLLNNPLEGPDQKSLIPVERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHHIEPPYFPLCKASLNSLVGGPVIWGGEPRAHAMAQVDAWQQLQTFFHNHLDGKKKTIPAKL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Q2Z6-1", "uniprot_id": "ACOT5_MOUSE", "id": "Q6Q2Z6-1", "name": "Acyl-coenzyme A thioesterase 5", "aln": "-----------------------MVPTVSLEPTGHSCWDEPLSIAVRGLAPEQPVTLRTALRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYKYDDLPKVIDILHLEYFEEAVTYLLSHPQVKGPGVGLLGISKGAELSLSMASFLKGITAAVVINGATVNVISTLYYKEESLPGLGMHLERIKVTKDGFKDIIDILNVPLEAPDQKSLIPLERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIVCYPKTGHHIEPPYIPWSIAAPHSYFDKPILLGGEPRAHAMAQVDAWQRLQTFFHKHLSGDKRPSPAKL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88267-1", "uniprot_id": "ACOT1_RAT", "id": "O88267-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "-----------------------MEATLSLEPAGRSCWDEPLSITVRGLVPEQPVTLRAALRDEKGALFRARALYRADAHGELDLARAPALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTICYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPLVE--QKSFIPVERSDTTFLFLVGQDDHNWKSEFYANEISKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLGGKSHGVSPKI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55137-1", "uniprot_id": "ACOT1_MOUSE", "id": "O55137-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "-----------------------MEATLNLEPSGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLVKRDVQTPFVVELEVLDGHEPDGGQRLAHAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKNMETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPLVD--KKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHAMAQLDAWQQLQTFFHKQLGSECLHVSPKI----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TX2-1", "uniprot_id": "ACOT1_HUMAN", "id": "Q86TX2-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "-----------------------MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T759-1", "uniprot_id": "A0A8N7T759_DANRE", "id": "A0A8N7T759-1", "name": "", "aln": "MYATLKCALKPFARNTLAKMHYSSGVSIRLLPSYKCSFEDPVHVTVSGLNPHQRVDLRSKITDEGGRDFKALATYQADDSGQIDLKRDSSLGGSFTGVEPMGLYWALKADTISCKFKLKDVTRPALVDIEVVSDD-----KVLAKVTNERHCLTDGVRRRPLNEDRIRGTLFMPPGKGPFPGILDTYILRGGHFELRAALLAKRGFAVLALAYQNYQDLPKSSDKFHLEYFEEGIDFLRQQPEVKGQKIGLLSISKSGDLALSMSTFLPDIAATVWINGCNANSVVPLYYKDMYIPPLTLDFKKKKITPLGLVDMLDVVKDPMSKEGLPSVIPIERAPGRFMFIASEANMNWRSAYHAKLACDRLKAHGKKNYELVKYEKAGHFIEVPYMPFCFANFHSVLKQPVLFGGEPKCHSEAQVDAWPRIINFFKKHLATADYNLSPMLEENIHEMSQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NZE7-1", "uniprot_id": "A0A8M1NZE7_DANRE", "id": "A0A8M1NZE7-1", "name": "", "aln": "MYAALKFAFMPFAR-SLAKVHYSSGVSIKLLPSYKCSFEDPVHVMVSGLNPHQRVNLRSKITDEGGRDFKASAIYLADDNGQIDLKRDSSAGGSFSGVEPMGLFWALKADLLSCKFKLKDVTRPALVDIEVVGEDE----KVLAKVTNERHCLSEGVRRSLVTEGRIRGTLFMPTGNGPFPGILDTYILKGGPFELRAALLAKRGFAVLALAYQNYQDLPKKADKFHLEYFEEGLDFLRRQPEVKGQKIGLLSISKSGDLALSMSTFLPDITAAVWINGCNANSLIPLYYKDMYIPPLTLDFKKKKMTALGLVDMLEVVNDPMSKEGLPTVIPIERASASFMFIASEADMNWRSVYHAKLACDRLKAHGKNNYELVKYEKAGHFIEVPYMPFCLAAFHGVLEQPVLFGGEPKAHSEAQVDAWQRIIIFFKRTLGS-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *: . ::*: : * ** *.* * **: : ** * *:* * * ** *::** * .: ****:*:***** **::.: :: :** * *::**:. . : *.:. :**: :. **** : .*:*.***:*. ******:* : .* :* **:*** :****:**** :*:**** : :::*****.: :* :*:*.* :*:*.***..:* ::*::** .*:*:* ***. : ** :* : : :: * * * *::: :: *: :.**:**: *:*:..: : **:* ::* ..**:***:.: ::: * :**.** **:* . * : . : ****: *: **:*** :: **:. * ", "identical_positions": 151, "similar_positions": 125, "identity": "33.26%" }, { "cls_id": "homologset.agr.HGNC:3313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CH84-1", "uniprot_id": "ELAV2_RAT", "id": "Q8CH84-1", "name": "ELAV-like protein 2", "aln": "--------------------------------------------------------------------METQLSNGPTCNNTANGPTTVNNNCSSPVDSGN---TEDSKTNLIDNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPN-----RRYPGPLAQQAQRFRLDNLLN----MAYGVK-RFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60899-1", "uniprot_id": "ELAV2_MOUSE", "id": "Q60899-1", "name": "ELAV-like protein 2", "aln": "--------------------------------------------------------------------METQLSNGPTCNNTANGPTTVNNNCSSPVDSGN---TEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPN-----RRYPGPLAQQAQRFRLDNLLN----MAYGVKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12926-1", "uniprot_id": "ELAV2_HUMAN", "id": "Q12926-1", "name": "ELAV-like protein 2", "aln": "--------------------------------------------------------------------METQLSNGPTCNNTANGPTTINNNCSSPVDSGN---TEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPN-----RRYPGPLAQQAQRFRLDNLLN----MAYGVK-RFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8S0A2-1", "uniprot_id": "A0A2R8S0A2_DANRE", "id": "A0A2R8S0A2-1", "name": "ELAV-like protein", "aln": "-----------------------------------MAVRLCDVASLLRSGSWAAEPWTG----QVIAAMETQLSNGPSCT-SSNGPNSVSNTCTSPVEMPNG--SEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYMEPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQFGRIITSRILVDQVTGVSRGVGFIRFDRRVEAEEAIKGLNGQKPPGATEPITVKFANNPSQKSSQALLSHLYQSPN-----RRYPGPLAQQAQRFRLDNLLN----MAYGVKSRFSPMTIDGVTSLAGINLPAHAGTGWCIFVYNLAPDADENVLWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAVAIASLNGYRLGDRVLQVSFKTNKTHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PBZ2-1", "uniprot_id": "M9PBZ2_DROME", "id": "M9PBZ2-1", "name": "", "aln": "MVEGQTAVQQQQQQPSGAGGASGVGSTTGSAGGPATANNVTNSQAQTNGGTTATTTAAAGAGSTTNAAVGQATANNAASNNNNNNNNTNNNNNNNATANNNNNNEPDPKTNLIVNYLPQTMSQDEIRSLFVSFGEVESCKLIRDKVTGQSLGYGFVNYVKQEDAEKAINALNGLRLQNKTIKVSIARPSSESIKGANLYVSGLPKNMTQSDLESLFSPYGKIITSRILCDNITGLSKGVGFIRFDQRFEADRAIKELNGTTPKNSTEPITVKFANNPSSNKNSMQPLAAYIAPQNTRGGRAFPANAAAGAAAAAAAAAIHPNAGRYSSVISRYSPLTSDLITN-GMIQGNTIASSGWCIFVYNLAPDTEENVLWQLFGPFGAVQSVKVIRDLQSNKCKGFGFVTMTNYEEAVLAIQSLNGYTLGNRVLQVSFKTNKNKQTXLLTKLAAVVNANAAAAALAANGLVLHNHHHHSNIGSINNNSNNSNGCSAAAFPLGKYVNHSSNNRQHNINNSTSNTSKQKPASTSNKQQSMAPPKRLASSTAATTGDLAATAATNSSSSSHSASSGDAGATGTAASSSSSSSSTNNNILKTSTKFIYNKPQNQYELLQQQLQLQQEFAQFLTNVANSAATPSSNGSANSTNQRNGGGTIGMGLGMSANSAGGGSGNKNSNGNNGYMPTWSNWFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*..:.. . *. .: .*. .... * *.***** *****.*:*:*::*** *:**:*****:***:************:. :*******:*******.****** ***** **:.**********.***.:**.*** :*:******* *::**:*:********:*.**:.*** *** .* .:*************.:... * :*: * :*. * * :: .* *:**:* * :*. . *: ..:************::*.:***:******* .******:::**************:**.:** ***** **:***********.::: ", "identical_positions": 211, "similar_positions": 89, "identity": "30.8%" }, { "cls_id": "homologset.agr.HGNC:33131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3X1-1", "uniprot_id": "M0R3X1_RAT", "id": "M0R3X1-1", "name": "Proactivator polypeptide-like 1", "aln": "--MNIMLCVLILWSGLLGATKASPISVPHECAKGSEVWCQDLQAAARCRAVRHCQSAVWS---KPTVKSLPCSVCQDVAAAASNGVNPDAKESDILASVMKTCEWLPSQESSAKCKWMVDNHSAAVLVMLRGAPGT----ALASVCTALTLCEPLQRHLAVATSERPLTQEDANEVMAPFLSNGALTFHPS----------------------------------------------------------------------------------------QMPVGAVCHDCVQLISRLQSALESNLTLAEVT--------------------------------------------------------------------------------VQNQCQSMGPGLAALCENYVHWQFVPAKQALQTLPPQEVCRKGGFCEEQRESAHWLAQVAAVDG---------------------------------------------------VPSLEMELPKK---------NELQMQLGLTCDVCLNVVQELDKWLETNSTEALISHALERVCSIMPESLVQQCITLVDTYGPNLVQLVS-KVTPEKVCETIRLCGSKR-------------------------QARSISRVATTTPPLLMDE-ENQGSFCQGCKRLLGVSSQNLDRKSTKRDILNAFKGGCRILPLPYVLQCNRFVAEYEPVLIESLRFMMNPTDLCKKMGACHGPKVPLLGTDQCVMGPRFWCKSPE--------------------------------------------------------------------------AAEMCDALEHCQRLVWKKPISRTNEQP----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1C1-1", "uniprot_id": "SAPL1_MOUSE", "id": "Q8C1C1-1", "name": "Proactivator polypeptide-like 1", "aln": "-----MLCALILWSGLLGAARASPISVPRECAKGSEVWCQDLQAAAKCRAVRHCQSAVWN---KPTVKSLPCSVCQDVAAAAGNGVNPGATESDILTSVMKTCEWLPSQESSAKCKWMVNNHSAAVLSMLSGAQET----DLASVCTALTLCEPLQRHLAETTSERPLTQEDANEVMAPFLSNGALSFHPS----------------------------------------------------------------------------------------QMPEGAVCHDCVQLISLLQDALESNLTLAEVT--------------------------------------------------------------------------------VQNQCQSMGPGLAALCENYIHRQFVPAKQTLQGLPPQEVCRKGGFCE--RESAHWLTRVAAVDG---------------------------------------------------VPSLEMEMPRT---------NELQMQLGLTCDVCLNLVQELDKWLVTNSTEALISHTLERVCTVVPEPLVQQCITLVDTYSPELVQLMS-KVTPEKVCETIKLCGSKR-------------------------RARSISRAVATTPSLPVDE-ENQGSFCQGCKRLLGMSSQNLDHKSTKRDILNAFKGGCRILPLPYVMQCNRFVAEYEPVLIESLKFMMNPTDLCKKMGACHGPKTPLLGTDQCVMGPSFWCKSPE--------------------------------------------------------------------------AAEMCNALEHCQRLVWKKPVSKINEQP----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUJ1-1", "uniprot_id": "SAPL1_HUMAN", "id": "Q6NUJ1-1", "name": "Proactivator polypeptide-like 1", "aln": "-----MLCALLLLPSLLGATRASPTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWN---KPTAKSLPCDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDS----APAQVCTALSLCEPLQRHLAT---LRPLSKEDTFEAVAPFMANGPLTFHPR----------------------------------------------------------------------------------------QAPEGALCQDCVRQVSRLQEAVRSNLTLADLN--------------------------------------------------------------------------------IQEQCESLGPGLAVLCKNYLFQFFVPADQALRLLPPQELCRKGGFCEELGAPAR-LTQVVAMDG---------------------------------------------------VPSLELGLPRKQ--------SEMQMKAGVTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVA-KITPEKVCKFIRLCGNRR-------------------------RARAVHDAYAIVPSPEWDA-ENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGACHGPRTPLLGTDQCALGPSFWCRSQE--------------------------------------------------------------------------AAKLCNAVQHCQKHVWKEMHLHAGEHA----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y125-1", "uniprot_id": "Q9Y125_DROME", "id": "Q9Y125-1", "name": "", "aln": "MERAGLLAVLALCCAFGVFAAATPLLGSSKCTWGPSYWCGNFSNSKECRATRHCIQTVWETQKVPVDTDSICTICKDMVTQARDQLKSNQTEEELKEVFEGSCKLIPIKPIQKECIKVADDFLPELVEALASQMNPDQVCSVAGLCNSARIDELYKNGIQAGLDGTVQNEDDSSEETELAMQPNQLSCGNCNLLSRLMHSKFAATDRDDMVETMLHMCGSLSSFSDACANIVLTYFNDIYDHVSKHLTTDAVCHVSGVCASRYHQHEEEKQPQEALVALDAGDDIPCELCEQLVKHLRDVLVANTTETEFKQVMEGFCKQSKGFKDECLSIVDQYYHVIYETLVSKLDANGACCMIGICQKNSASSMKDVPIMPLLPVIEPAQVKITIEKLEKHEKKQLGASEPKFSQQEILDMQLPIDHLMGAANPGALVEGGELCTLCEYMLHFIQETLATPSTDDEIKHTVENICAKLPSGVAGQCRNFVEMYGDAVIALLVQGLNPRDVCPLMQMCPKNLPKKEDVEVFNPQPASDEQDPPTCPLCLFAVEQAQMKIRDNKSKDNIKKVLNGLCSHLPNEIKEECVDFVNTYSNELIDMLITDFKPQEICVQLKLCPKTTYALWDLRISLEDDVDGEDKSSSEEISFNDIESLEELPPQLAFDPGFTAAPNCLICEELVKTLEKRMGKHPTRDSIKHILEESCDRMRKPMNTKCHKVIDKYGDKIADLLLKEMDPKLICTELGMCILADLDDLEVDEALKYDVIALPRQDNKLSSSIKEPPTCVLCEFIMTKLDADLKNKTEQDDIKRAIEAVCNRLPATVRKQCDTFVDGYASAVLKLLSDVPPKQVCQKLQLCFSVAVTDEVLECGVCHGVTQALLPFLREKKDNVSEVTALQMTSVGCENLPAKYYKICSEMISIYGSSIKNLAKRPYIDQSHICAEIGKCFESEKSSLAFARISA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..* * .: : *:* . :*: *. ** ::. : .* *. :* :**. *. .. * :*:*:.: * : ::.. .*.:: . :*: :* : . * :.: . . :: * . . * :*.: : * :. : .::*: * : . *: : . *. * : :. *:..: :* * ::.. :.: :.:*.. . :.:: : :* .: : * : . * :* : : .. * . : :*:. : : ** :*: *:: : : *.:: *.:.*: :*: :* : ::*: :*:**. .*:::: ...*:::* ::** . . : * * . .. * *:.*: .:.: :.*: .* :: .* : * :*::.: :* : : * *:* :*.::* * . * .*:. : : . ::*: :: * . .. . . ", "identical_positions": 81, "similar_positions": 200, "identity": "8.5%" }, { "cls_id": "homologset.agr.HGNC:33132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9F8-1", "uniprot_id": "G3V9F8_RAT", "id": "G3V9F8-1", "name": "", "aln": "MTPAVLLAILCLRLISSSPAPDPVLDAEWQKWKIKYEKTYSLEEEGQKRAVWEQNMKKIKLHNGENGLGKHGFTMEMNAFGDMTIEEFRKLMIEIPIPTVKKENSVQKRQAVNVPNFINWRKRGYVTPVRRQGRCNACWAFSVAGAIEGQMFRKTGQLIPLSVQNLVDCSRTQGNLGCYLGNTYFALQYVKENGGLESEATYPYEGKEGSCRYHPDNSTASIAGIEFVPKNEHALMNAVATLGPISVAIDARHESFLFYRNGIYHEPNCNSSVVTHSMLLVGYGFVGEESDGRKYWIVKNSMGNKWGNRGYMKIAKDQGNHCGIATYALYPRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NE16-1", "uniprot_id": "CATL3_HUMAN", "id": "Q5NE16-1", "name": "Putative inactive cathepsin L-like protein CTSL3P", "aln": "-------------------------------------------------------MKMIEQHNQEYREGKHSFTMAMNAFGEMTSEEFRQVVNGFQNQKHRKGKVLQEPLLHDIRKSVDWREKGYVTPVKDQCNWGSVRTD----------VRKTEKLVSLSVQTWWTALGFKAMLAAFLENHYFASSMLPTMEAWTLRKPFHMKKSSGDWKVQGHRGAS----------GESLLASGESQQSPEVAQYSGKHQ--------------VQCHLIEEALQMLSGGDEDHDED-------------KWPHDMRNHLAGEAQV-------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *: ** * ***.*** *****:** ****::: : . :* : :*: :: : ::**::******: * . .: : .*** :*:.****. . :. *..:* * *** . : . . .: : ..*. : : ...:: .* * .. : .* . ..:*: :. :: .:: ::. * ..:.* ** : ::* : ", "identical_positions": 58, "similar_positions": 80, "identity": "17.42%" }, { "cls_id": "homologset.agr.HGNC:3314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATM0-1", "uniprot_id": "A0A8I6ATM0_RAT", "id": "A0A8I6ATM0-1", "name": "ELAV-like protein", "aln": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDK-------------ITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATG-VSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNP---SQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVK-------RFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60900-1", "uniprot_id": "ELAV3_MOUSE", "id": "Q60900-1", "name": "ELAV-like protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDK-------------ITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATG-VSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNP---SQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14576-1", "uniprot_id": "ELAV3_HUMAN", "id": "Q14576-1", "name": "ELAV-like protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDK-------------ITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTG-VSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNP---SQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYA7-1", "uniprot_id": "A0A8M3AYA7_DANRE", "id": "A0A8M3AYA7-1", "name": "ELAV-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MVT-IISTMETQVSNGPSGTSLPNGPVISTNGATDDSKTNLIVNYLPQNMTQEEFKSLFGSIGEIESCKLVRDK-------------ITGQSLGYGFVNYVDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKDMEQLFSQYGRIITSRILVDQVTAGISRGVGFIRFDKRNEAEEAIKGLNGQKPLGAAEPITVKFANNP---SQKTGQALLTQLYQTAARRYTGPLHHQTQRFRLDNLLNASYGVKSSLSVLPRFSPITIDSMTSLAGVNLTG-PTGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTSKQHKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16914-1", "uniprot_id": "ELAV_DROME", "id": "P16914-1", "name": "Protein elav", "aln": "----------------------------------------MDFIMANTGAGGGVDTQAQLMQSAAAAAAVAATNAAAAPVQNAAAVAAAAQLQQQQVQQAILQVQQQQTQQAVAAAAAAVTQQLQQQQQAVVAQQAVVQQQQQQ----------AAAVVQQAAVQQAVVPQPQQAQPNTNGNAG-SGSQNGSNGST-ETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELEAIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAFLNPQLVRRIGGAMHTPVNKG-LARFSPMAGDMLD------VMLPNGLGAAAAAATTLASG--PGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . *. .. * : .*. .:**:* :::**********.**::*::***.*:*:*** **:*** .*********** *:**::*:*.****:**.******:***** :*:.************:*:::* :*: :* ******* : . ::********** ** .** .*** .* ..::**.***:*.* *: * : * .** *.:* .:: * .: : .: : * :.. :. * . :* .*..: **:***:**::*:.*********** .**:::* ***:***:***:*********** :**** :*:*********.* : ", "identical_positions": 184, "similar_positions": 99, "identity": "33.7%" }, { "cls_id": "homologset.agr.HGNC:33145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYF7-1", "uniprot_id": "WASH1_RAT", "id": "B2RYF7-1", "name": "WASH complex subunit 1", "aln": "MTAVKTQHSLAGQVYAVPLIQPDLRREEAIQQVADALQYLQNISGDIFSRISQRVELSRRQLQAIGERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPEHLQEYNSVFTGALD-PGLQRRPRYRIQSKHRPLDERALQEKLKYFPVCVSTKSEPED---------EAEEGLGGLPSN-ISSISSLLLFNTTENLY----KKYVFLDPLAGAVTKTHTMLGTE-EEKLFDAPLSISKREQLEQPAPENYFYVPGLGQVPEIDVPSYLPDLPGVADDLMYSADLGPGIAPSAPG--AIPELPAFHTEVA-----------EPFQPEREDGALLAPPPPPPPPPPPPPPAPTAVVSAPQPPMSPDVVTVTGKVAREEDSGSGEAHSASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGKGP-----GTGTSEGPGGAFSRMSDSIPPLPPPQQ------PAGDEDEDDWES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDD8-1", "uniprot_id": "WASH1_MOUSE", "id": "Q8VDD8-1", "name": "WASH complex subunit 1", "aln": "MTPVKTQCSLAGQLYAVPLIQPDLRREEAIQQVADALQYLQNISGDIFSRISRRVELSRRQLQAISERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPEHLQEYGSIFTGALD-PGLQRRPRYRIQSKHRPLDERALQEKLKYFPVCVNTKSEPED---------EAEEGLGGLPSN-ISSISSLLLFNTTENLY----KKYVFLDPLAGAVTKTHTMLGTE-EEKLFDAPLSISKREQLERQAPENYFYVPDLGQVPEIDVPSYLPDLPGVADDLMYSADLGPGIAPSAPG--AIPELPAFHTEVA-----------EPLQPELENEVLLAAPPPPPPPPPPPPPAPTALVSTPQPPMFPDMATAAGQVAREEDSSSSMAHTASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGKGP-----STGTSEGPGGAFSRMSDSIPPLPPPQQ------PAGDEDEEDWES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VEQ5-1", "uniprot_id": "WASH2_HUMAN", "id": "Q6VEQ5-1", "name": "WAS protein family homolog 2", "aln": "MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQQVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQD-PGLQRRPRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPED---------DAEEGLGGLPSN-ISSVSSLLLFNTTENLY----KKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPGIANDLMYIADLGPGIAPSAPG--TIPELPTFHTEVA-----------EPLKVDLQDGVLT-----PPPPPPPPPPAPEVLASAP--PLPPSTAAPVGQGARQDDSSSS--ASPSVQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSMKERKLEKKKQKEQEQVRATSQGGHLMSDLFNKLVMRRKGISGKGP-----GAG--EGPGGAFARVSDSIPPLPPPQQ------PQAEEDEDDWES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG59-1", "uniprot_id": "WASH1_DANRE", "id": "A4IG59-1", "name": "WASH complex subunit 1", "aln": "MVRMTQKRYLEGQVYSVPLIQPDLRREEAVHQITDALQYLEMISTDIFTRVSESVEKNRAHLQSVTDRIKLAQARVQKIKGSKKATKVFSSAKYPAPEKLQDYSSIFTGAVD-PASQKRPRIKVQSKLRPLDDKAQQEKLMYLPVCVNTKKRSED---------ETEEGLGSLPRN-VNSVSSLLLFNTTENLY----KKYVFLDPLAGAVTKTHTTLETEKEDKPFDAPLSITKREQLERQTAENYFYVPDLGQVPEIDVPSYLPDLPGIADDLMYSADLGPGFAPSVPASNSIPELPSFGTDHD-----------ESSGSDSQ-FKLEAPPPPPPPPPPPPEPTHVPVPPPGTSAAPPPPPPPPPMTADNTDASSPAPPTGTVKGAPSEVVQPSNGRASLLESIRNAGGIGKANLRNVKERKMEKKKQKEQEQVGATVSGGDLMSDLFNKLAMRRKGISGKGPAGQGDSSEAPASSGGAFARMSDVIPPLPAPQQ------SAAD-DEDDWEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JW27-1", "uniprot_id": "WASH1_DROME", "id": "Q7JW27-1", "name": "WASH complex subunit 1", "aln": "----MEESPYLHSPYQVAIIATDLHHEDTIIQAAQSLDCLHKTINSIFERIDARLARNGSKVEDINNRVKRAQAKIDALVGSKRAIQIFAPARFPASDVLAPLPATFPQVAANPLMEQQVDQLPQGTYSSHSAADQKPDDADIFFHVRGDREQESPLVAERKITNRTAGLGILPAGGVRSVPSLMRFNTNEFAYGEDLNAWKRSLPPQNARRVASQSTQLTGEKQLAPAPHSLAHGTTKLATPAGDLRYNPAALAAPAIDVPLDLPDLPGIANDLQYEPVEEQTPIAPSQQFGDLPELPDLGLEEQDIIVQAIAAQTHIPGPVRRKSVGQCPSPVTAAPPPPPPPPPPPPPPPPAQTSAIPSPPPFPTKGAVKPLSPSLATPLNMPQPPPATEDP---RSELMAAIRNAGGVHGGRLRSPAAAPLDVVDNSRSKAGGAVT--GDLMADLHNKLMLRRKGISGSQN------PVEATAGNPLMQQLSRVIPPPVQPRKGSKSSDEHSEDDEDGWN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *.:* .**::*::: * :::*: *. .** *:. : . ::: : :::. ***::: : ***:* ::*:.*::**.: * : *. . * ::: *.. . . : . : . * . . *. : *** ** . : *:.**: ***.* * : : * .* : *.: ** *::: . : * * .* **** ******:*:** * . .. :**** : : . . ...***** *. .. . . . .. . .: .* . :* *: *: :**:***: ..**. :: .:...: *. *.**:**.*** :*******. . . . : ::* *** *:: .: **:.*: ", "identical_positions": 110, "similar_positions": 139, "identity": "21.36%" }, { "cls_id": "homologset.agr.HGNC:33146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY13-1", "uniprot_id": "A0A8I5ZY13_RAT", "id": "A0A8I5ZY13-1", "name": "", "aln": "-----------------------MDDKLHSVKVFVLVEDEQWKIIGTGQISSKYIERLQGVCLLVHSESDGSQIMECKIYPNVPYHKQRGEIIVWSEAKNHGMAIYFQEPSGCQEIWEDICQVQGKDPSVEITQEVTDDLET--FADLLPIGNLFEMPNCELN----TLEHIADLFTFVDKTPNH-RERMAMVLEKGSYIKKLLQLFNTCEKLKNMEALHFLNNIIKGILFLDDTRLLNIMFSDEFFMDVVGCLEYDPALDQPKQ-YREFLLQN-AKFREIMPITNSQLRQKIQETYRMQYVYDIVLPAPSIFDSN-LLSDLNAMIIFNKSEIITMLQDDENFLLEALSQLKDNTVGY---------ERWYELLLFFKEFCIFAKALENQEKDELLKTLIKLGIMSALKVLVHMH-DYQIQKAALDIFPYLVEYNPCLVREYLLEEAQDSEDNDELLINVMIKQMIYDPDPEFSKDIILPAVLRALLDPENMHVTANGCEKAKFLNFFYARCMGNLIAPILSTTVENDTDDN------MVNICPN-YQNAQLLGVILEILTFCVQYHSTYMKNYILNNNLLSRILMLMSSKHTFLILCAVRFMRKIISLKDEIYNLYIIKKNLFEPIVNAFMHNGTRYNMLNSAIIELFEFIRQENIKSLIANIVENFFIAFESIEYVQTFKGLKTKYEE-------EKKRESGIRRNLYNVIYQKIYCRHIKVMELK--------------------VKADICCREITEEE-----------------------------------GAILPMGKE---FPS----------------HYDIIMKIKETN--------------ENENVIEHP------------------KSNETSKCSSSCGDASSNKMSMVHCS------------------------------------------------SLVPLVDYP------------YDTDGESDDDPYGND--------------------------ENDDEDKDNEPLSKRPNLSS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ADI4-1", "uniprot_id": "A2ADI4_MOUSE", "id": "A2ADI4-1", "name": "", "aln": "-----------------------MDDKLHSVKIYVMVEDEQWKGIGAGQISSKYIERLQGVCLIVQSESDGSLIMECKIHPNVPYHKQRGEIIIWSETKNHGMAIHFQEPNGCQEIWEDICQVQGKDPNVEITEELTDNLKT--FEELLPIWNLVEMQNCELH----TLENIADLFTFVHETPSH-KERLVLVLEKGVYIKKLLQHFNTCEKLKNMESLYYLNNIIKGILFLDNTHLFNIMFSDEFFMDMVGCLEYDPALDHPKQ-YREFLTQN-AKFKEILPITHFQLRQTIQQTYRMQYVHDIVLPIPSICESN-LLYGLNTMIIYNKIEIITMLQDDENFLLEVLARLKDNTVGN---------DRRHELLLFFKEFCTFAKTLENLEKHELLKTLINLGVMSALKAVVHMH-DYQIQIAALDIFPYLVEYNPCLVREYLLDEAHDTDD-DDLFLNIMIKQMICNSDPRFSQGIILPAILCALLDPENMHVTANGCEEKEFLNFFYTRCINNLIAPILSATVEKENANN------RANICPDNYQNAQLLGVVIEILTFCVQYHSTYIKSYILDNNLLSRILVLMTSKHTFLILCAVRFMRKLIGLKDEIYNLYIIKENLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVENFFISFESIEYVQTFKGLKIKYEE-------EKN-ECQVRRNLLNVVCQKIYCICTNDMGLK--------------------VKSDICHRRITETK-----------------------------------EAILPNRRD---FPS----------------HYGIIMKIEETN--------------ESESAIEGQK----------------IKSSEAFERCPSHGDASATRMSRSHCS------------------------------------------------SLVPLVNYP------------YDTDDENGDDPYGND--------------------------NDEDE----EPPQKRPNLSS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3V0Y1-1", "uniprot_id": "P4R3C_MOUSE", "id": "Q3V0Y1-1", "name": "Protein PPP4R3C1", "aln": "-----------MTWPSEARPNINMEYRLHTVKVYVMMEDKQWKNVGTGQISSKYSEQLQGVCLLVHSLSDGSPIMECKIHPNVPYQKQQGKIIIWSEAKNHGMAIHFQEPNDCQEIWEDICQIQGKDPHVEITQELTDDLET--FEHMPLIWNWVEMSNCEIH----TLKNIAELFPFVFEMPSQ-KERLALFLENEGYIKKLLQLFHTCEKLKNMEGLYYLHNIIKGILFLNNTRLFNIMFSDEFFMDIVGCLEYDPALDQPKQ-YREFLTQN-SKFKEVIPIIHSQLRQKIQQTYRMQYVHDIMLPTPSIFQTN-LLSDITTMIFFNKINIITMIQEDENFLLEVFSQLKDNSIGD---------ERRIELLLFLKEFCEFAKTLQSQKKNELLKTLIKLGIMSVLKVVVHMN-DYQIQVGALDIFAYLVEYSPCLVRAYAMEEAQDSEDNDDLLINIMIKQMICDFDPEFSQGIIMTAVLHELLNPENMRTTAKGCERKVFLNFFYKRYMRKLIAPILSIRVKYDSNDN------RVYICPDNYQNAQLLGAVLEILTFCVQYHSMYIKHYIFSNNLLRSILVLMSSKHTFLILCAVRFMRKIIGLKDKMYNHYIIKKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRKENITSLIVNIVENFFRAFKSIEYVQTFKGLKTKYEE-------EKKRKSQRRKNLHSIMHPKMYYRHIEDMEVK--------------------VKADICCRGIIEEEERQ---------------------------GGGEEGAILPMGSD---FTN----------------NYDIFMKNKDTN--------------ESESAIEGQK----------------IKSSEASECCPSHGDASATRMSRSHCS------------------------------------------------SLVPLVDYL------------YDTDDENDDDPYGNDKH------------------------EDEHEDEDEEPPPKRPNLST-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M5R2-1", "uniprot_id": "A0ABK0M5R2_RAT", "id": "A0ABK0M5R2-1", "name": "", "aln": "------------MWPSKVRPEMNMKDKLHRVKVYAMLEDKQWKDIGTGQISSKFIK-LQGMCLFVHSESDGSPIMECKIHPNVPFKKQQGEVIIWFEAKNRGMAIHFQDPNGCEEIWKDICQVQGKDPNVEITQELTDDVEN--FENLPLNWDQIEMLNYKFP----TLKNMANLLTIIGEMPRL-KERLVLVLENESYIKKLLQLFNTCETKLNIEGLHYLNSVIKGILFLNDTRLFKIMCSDEFFMDVVGCLEYGPDLNQPKR-HREFLTQN-VKFKEVIPITQTQLRQKIQQTYRLQYVHDIMLPTPSMFQAN-LLSDLTTMIFFNKIEIITMLQEDEKFLLEVFTQLKDNTVGD---------DRRYELLLFFKEFCVFAKTLQSQDKNALLKTLIRLGIMNTLKVVVHMN-DNQIQIAALDIFAYLVEYNPRIVQAYAMEEAQNSENNDDLLINIMIKRMICDSDPEFSRGIILPAVLHALLDPENMHVTANGCERKGFLNFFYTHCMNTLIAPILSTTVQNYSDEN------RANICPDNYQNAQLLEVILEILTFCVQCHSMYIKNYILTNNLLSRILVLMSSKHTFLILCALRFMRKMIGLKDEMYNLYIIKQNLFEPVVRTFMHNGPQYNMLNSAIIELFEFIRQENIKSLIANIVENFFTAFESVEYVQTFKGLKTKYEE-------EKKRESRIQRYLHNMIYQKICCRHIQVMEVK--------------------VKADICCRGITEEKEEEKEEGGGGGGGGG---------------GGGGGGAIVPMGTD---FPN----------------HYELFMKIKETN--------------ERENEIECPK----------------RKLSEVSKCSSYESDDSDNGMSRVHCS------------------------------------------------SLVPLVDYP------------YDTDGDNDDDPYDKD--------------------------ENEDE----EPPQKRPNLRS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZMV5-1", "uniprot_id": "P4R3C_HUMAN", "id": "Q6ZMV5-1", "name": "Protein PPP4R3C", "aln": "-----------------------MAGLRYSVKVYVLNEDEEWNNLGTGQVSSTYDEQFQGMSLLVRSDSDGSVILRSQIPPDRPYGKYQETLIVWYEAENQGLVLKFQDPAGCQDIWKEICQAQGKDPSIQTTVNISDEPEED-FNEMSVISNMVVLPDCELN----TLDQIADIVTSVFSSPVTDRERLAEILKNEAYIPKLLQLFHTCENLENTEGLHHLYEIIKGILFLNEACLFEIMFSDECIMDVVGCLEYDPALDQPKR-HRDFLTND-AKFKEVIPITNSELRQKIHQTYRLQYIYDILLPVPSIFEDN-FLSTLTTFIFSNKAEIVSMLQKDHKFLYEVFAQLKDETTHD---------DRRCELLFFFKELCSFSQALQPQSKDALFETLIQLGVLPALKIVMIRD-DLQVRSAAAVICAYLVEYSPSRIREFIISEAHVCKD-SDLFINVIIKQMICDTDPELGGAVHLMVVLHTLLDPRNMLTTPEKSERSEFLHFFYKHCMHKFTAPLLAATSEHNCEEDDIAGYDKSKNCPNDNQTAQLLALILELLTFCIQHHTFYIRSYILNKDLLRKALILMNSKHTHLILCVLRFMRRMICLNDEAYNNYIIKGNLFEPVVNALLDNGTRYNMLNSAILELFEYIRVENIKPLVSHIVEKFYNTLESIEYVQTFKGLKIKYEK-------ERDRQSQIQKNLHSVLQNIVVFRGT-IEEIG--------------------LEEEICFMEDAGEVVMPPLEDDDEFMETK---------------RTQEGEAVMPPLEDDDKFTETKRTHQEGEAVMPPLEDDDEFMETKRNQ--------------EHEGKVDSPK----------------RTSSGDFKFSSSYSACAAIGTGSPSGS------------------------------------------------SVVRLVDHP------------DDEEEKEEDEEEKEE--------------------------DKEDE----TSPKKKPHLSS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFS5-1", "uniprot_id": "PP4R3_DROME", "id": "Q9VFS5-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "----------------------MTTDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQDTLIVWSEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPPIELPPCELS----RLEDISETIQSCLSTPLR-KEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFEIFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKK-HRQYLKQL-AKFREAVPIKNLDLLAKIHQTFRVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDDERYLLDVFAVLTDPTTGD---------AKRRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMN-DKKTKSASIDILTAIVEFSPLVVRNYTLNQAN-RPEVERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENMLT-----EKGDFLNFFYKYSVQTLVAPVILNTIGDRPQNE-------------DYQTAQLLGIVLDILSFCVEHHSYHIKNFLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRYNLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMENRTDGGLPIIRSGGRFRRDQRQMEEEEEMWFNEEDDFTEEIDTYNNVMKSVSEKNGPQTQNQQKSSPPHSTSPHSGLLGSLSTTASSTATSATSGAPVASGSSSPEAISADEQTQAAVHLAAAALQHHQQQQQQQQQNPFQQQTQPEIAELQQQLSSVEAPQSQELELSQSAAASASPTSSSSSLEASTSSSSASSSSSSSSSSSPPGSSAAASLCDSATVAAVAASQFLSTIATAMAASVTAAAATNSSPSISPAPAVSSPDIENADAQLPPSDDASSPASGEQDANSTEGTSSEADKTTAKKGLVDYESDSGEDDYEEDEYSEGPQAQKRARQA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40164-1", "uniprot_id": "PP4R3_YEAST", "id": "P40164-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "MSLPGTPTTSPTPMDEDTEQAVSVNTEPKRVKVYILE-NNEWKDTGTGFCIGEVDEGKFAYLVVSDEDSPTETLLKSKLEGNIEYQRQEETLIVWKDLGGKDIALSFEESMGCDTLCEFIVHVQR-NIESNISLVTVKSSDNGLGSVHDIITGPVTLPSNDQQQNSQTLLEALKILNENTSFDFLKNETIEFILQSN-YIDTLISHFHKAEEEKIPKDLFLLSNIIKTLILYNKRDILESMVEDDRIMGIVGILEYDTEYPTSKANHRKYLGSKGPNFKEVIPLENEDLKIIMKKCFRLQFLKDVVLVR---FLDDHNFNLISEIVMDLETCIIDFLQVG-TFLDRLIELYDTKTLPESSSEKEKFVQKRKDGIRLLQQCVQMSINLDAVDRSKFYKTLVRKGLFKVLDYAFHMETDSNVRILATDTIITIIEHDILLIHNVQNEDSFKRQHKSAPDDKSSHRKYPQDYSSSTDSKLLLILSTILLSD------------RSPGLREQVVQALNTLLHPEGCVGNGEGSYDLMG----------RSNYEAKNTSEDFPSFSYGLNSDSINLNNYHYSSDEMNNLEPESESEFQVMEYFANFYNKIAPILFGPLIKKDITTE---MAEIDGQIEKVTKDDLLLIHLVKLVSFVCTEHDRVLSRRFILENGILDSVSKLIGGNHMMQLRLTAVR----CIKNLMCLDDKYYHRYMISKNLYAPVFKLFQEN-------------------IDKNNLANSCIQDFFRIIITECRAYQSDG------------HNRKEKTNGSYDGNGNDVKTNVNNNRTNFTILNKYLVQTYGDVLRKATDIP--------------FIQDMLETGEEN--------------QPDHSSFENSIEGGNDISVNMSTDGFAS-----------------------------------------------NHLEDIDIK------------NVKRLHSEIEHFENDP-------------------------HYSGDQLAFKKSVDQMNAST-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:: : :.:*. *:* . : . :. * . ::..:: : : : . :*:* : . .:.: *:: .*: : : * : * : : : .. . . : . * . . . . .* : *:. ** .*:. *: .* : *. * .::* ::: :. ::: * *: ::.:** ***.. .* :*.:* . :*:* :*: : :* ::: :*:*:: *::* : : :. ::: : *: ::* . :* : : : : : :::: : *: : : :** *:: .*. . . * : : : ::*.. :: .:: . . : .: : .. . : : * : . *. : .: * : *: : ::: :: .: :. : .: : * . : . : * . : * . . : : : : ::* :::*..:: *. * :: : . : : : :: : . : . . . : . :: : . . . : . :. : :. . : : . ", "identical_positions": 62, "similar_positions": 235, "identity": "5.97%" }, { "cls_id": "homologset.agr.HGNC:33147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A571BGB0-1", "uniprot_id": "A0A571BGB0_MOUSE", "id": "A0A571BGB0-1", "name": "", "aln": "---------------------MENSKLTKKKAGQKR---------------------------------------------------------------QRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDEIDSVHALELYKDKRVLSLKVIAKRVVSSGVTDSSFVDAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGNLQIMEGISDPPSLDNDLE-LVDGLIGKHVENTNDDGSKRDGLIIYQIETKPRVYLIKYEDDVHIHVTHLEKEF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0N4SW15-1", "uniprot_id": "A0A0N4SW15_MOUSE", "id": "A0A0N4SW15-1", "name": "", "aln": "---------------------MESSKLTKKRAGRKR---------------------------------------------------------------QRSRSPALLKRNIVGCRISHKWKEGDESITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVIAKRVVSSGVTDSSFVDAIVGKEVNHLFEGEHGSKEEWRGMIRSQVPILDNSFYITYERYPILYTYQLLDDFKEGDLQIMEGISDPPSLDIDLE-LVDGLIGKHVENTNDDGSKRDGLIIYQIETKPRVYLIKYEDDVHIHVTHLEKEF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1B0R2-1", "uniprot_id": "B1B0R2_MOUSE", "id": "B1B0R2-1", "name": "", "aln": "---------------------MESSKLTKKRAGRKR---------------------------------------------------------------QRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLE-LVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BPZ2-1", "uniprot_id": "SPI2B_HUMAN", "id": "Q9BPZ2-1", "name": "Spindlin-2B", "aln": "MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKK---------------------------------------------------------------QRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKKS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NVE3-1", "uniprot_id": "SPI2C_MOUSE", "id": "Q6NVE3-1", "name": "Spindlin-2C", "aln": "MKTPHKKGAAKEQMGEGVGHHIGSTTIKKKKASQKR---------------------------------------------------------------QRSRSSS--RRSIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERILKLKILPDKVSFSGVSDVRLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMNAWFYITYERDPVLYMYQLLDDYKEGDLRIMPESSASPPADREPEGVVDGLIGKHVEYTKEDGSKRTGKVIHQVKAKPSVYFIKFDDDFHIYVYDLVKKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LUT3-1", "uniprot_id": "F1LUT3_RAT", "id": "F1LUT3-1", "name": "", "aln": "---------------------MENAKMNKKRAGQKR---------------------------------------------------------------QRSRSPTPPRGNIVGCRISHEWKEGDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKVLSNRVASSQVIDPSLADAIIGKAVEHVFEGEHGSKDQWRGMVLGQAPILDASFYITYEKDPVLYMYQLLDDYKEGDLRIMAGSSEPPPLDIDLE-LVDGLIGKHVEYTKDDGSKRVGMVIHQVEAKPTVYFIKFEDDFHIYVYDLVKQF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LPW6-1", "uniprot_id": "F1LPW6_RAT", "id": "F1LPW6-1", "name": "", "aln": "MEPSSTQKAQEQHTSKASGQDVEKEKMNKKRAGQKRKMENETTNRRRAGQKRQMENETTNRRRAGQKRQMENETTNRRRAGQKRQMENETMNRRAGQKRQRRRSPTPPRRNIVGCRISHEWKEGDEPITHWKGTVVEQVPVNPSLYLVKYDGVDCVYGLELYKDKRVRSLKILSNNVGSSQATDPSFADTIIGKAVEHVFEGEDGSKDEWKGIVLGQAPVLDANFYVTYENDPVLYMYQLFEDYREGDLRILEGFDEPPPLDIPVE-LLSFLVGTCAEYTTDDGSKRVGMVIHQVEGNPSVFLVKFPDDVHIYVCSLVKIR-", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:.**:..:*: ** *..: : .******** ****** **:*:***::***:********** :*.*:.***::*:*: .**::...* * * :.::*:** *:*:****.***::*:*:: .*.*::. **:***. *:** ***::*::**:*:*: . .*. : ::. *:*. .* *.:***** * :*:*:: :* *:::*: **.**:* * * ", "identical_positions": 106, "similar_positions": 84, "identity": "32.92%" }, { "cls_id": "homologset.agr.HGNC:33148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0H3-1", "uniprot_id": "SUMO1_RAT", "id": "Q5I0H3-1", "name": "Small ubiquitin-related modifier 1", "aln": "MSD----QEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G2XKQ0-1", "uniprot_id": "SUMO5_HUMAN", "id": "G2XKQ0-1", "name": "Small ubiquitin-related modifier 5", "aln": "MSD----LEAKPSTEHLGDKIKDEDIKLRVIGQDSSEIHFKVKMTTPLKKLKKSYCQRQGVPVNSLRFLFEGQRIADNHTPEELGMEEEDVIEVYQEQIGGHSTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SZR5-1", "uniprot_id": "SUMO1_DANRE", "id": "Q7SZR5-1", "name": "Small ubiquitin-related modifier 1", "aln": "MSD----TETKPSSDG-GEKKDGEYIKLKVIGQDNSEIHFKVKMTTHLKKLKESYSQRQGVPVNSLRFLFEGQRITDNLTPKELGMEDEDVIEVYQEQTGGCRND", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12306-1", "uniprot_id": "SUMO_YEAST", "id": "Q12306-1", "name": "Small ubiquitin-related modifier", "aln": "MSDSEVNQEAKPEVKP--EVKPETHINLKVS-DGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGATY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:**. . : *:*:* :..***.**:* ** *::* :::.:*** ::*****::* ** : **::*.**::*:**.::** ** ", "identical_positions": 42, "similar_positions": 32, "identity": "40.0%" }, { "cls_id": "homologset.agr.HGNC:3315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09032-1", "uniprot_id": "ELAV4_RAT", "id": "O09032-1", "name": "ELAV-like protein 4", "aln": "--------------------MEWN-----------------GLKMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG---VSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61701-1", "uniprot_id": "ELAV4_MOUSE", "id": "Q61701-1", "name": "ELAV-like protein 4", "aln": "--------------------MEWN-----------------GLKMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG---VSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26378-6", "uniprot_id": "ELAV4_HUMAN", "id": "P26378-6", "name": "ELAV-like protein 4", "aln": "--------------------MEWN-----------------GLKMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG---VSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IEW8-1", "uniprot_id": "ELAV4_DANRE", "id": "A0A0R4IEW8-1", "name": "ELAV-like protein 4", "aln": "MFEISRTLNAALLSNEGSTETQWRQADLPQLQGWAEKGLLTQPKMIISNMEPQVTNGPNSATANGPSSNSRSCPSPMQTGGSNDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGPTGGSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAAEPITVKFANNPSQKTSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVK--------------RFSPITIDSMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *****.*****:***.* *:******.*.********.:.********************************************************************************************************************************* ******************************:**************:**************************************** ********.************************************************************************************************:***", "identical_positions": 351, "similar_positions": 15, "identity": "82.59%" }, { "cls_id": "homologset.agr.HGNC:33154", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ44-1", "uniprot_id": "D3ZZ44_RAT", "id": "D3ZZ44-1", "name": "", "aln": "MAGH-----GWG----APWVLVAAATLLHACGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQG-RHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPP-EPSDMPCADDECFSGDGTTPLVVLTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAV-AAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESGETPKATKGNYIEVRTGEPPERRGCELSRPAPETQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAATGPPRASTSSSGSARSPRTFRAETAGAHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPP--PPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8T7-1", "uniprot_id": "ELFN1_MOUSE", "id": "Q8C8T7-1", "name": "Protein ELFN1", "aln": "MAGH-----GWG----TAWVLVAAATLLHAGGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQG-RHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPP-EPSDMPCADDECFSGDGTTPLVILTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAV-AAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESSETPKATKGNYIEVRTGEPQERRGCELSRPG-EPQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAAPGPPRASTSSSGSARSPRTFRAEATGTHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPP--PPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7U0-1", "uniprot_id": "ELFN1_HUMAN", "id": "P0C7U0-1", "name": "Protein ELFN1", "aln": "MAGR-----GWG----ALWVCVAAATLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGQG-RRGHR-SILSKLQSVCTEDSYAAEVVGPPRPASGRSQPGRSPPPPPPPEPSDMPCADDECFSGDGTTPLVALPTLATQAEARPLIKVKQLTQNSATITVQLPSPFHRMYTLEHFNNSKASTVSRLTKAQEEIRLTNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEKHKKAASAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAG-EVEQYKLVESADTPKASKGSYMEVRTGDPPERRDCELGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGPVSVAEPPLVLLSEPLAAKHGFLAPGYKDAFGHS-LQRHHSVEAA-GPPRASTSSSGSVRSPRAFRAEAVGVHKAAAAEAKYIEKGSPAADAILTVTPAAAVLRAEAEKGRQYGEHRHSYPGSHPAEPPAPPGPPPPPPHEGLG-RKASILEPLTRPRPRDLAYSQLSPQYHSLSYSSSPEYTCRASQSIWERFRLSRRRHKEEEEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBN8-1", "uniprot_id": "A0A8M2BBN8_DANRE", "id": "A0A8M2BBN8-1", "name": "", "aln": "MASRRASEACYGGMVKSAFFWSVAIICLTYMGGVKGDCWLIEGEKGFVWLAICSQNQPPYEAIPQHINSTIVDLRLNENKIKSIHYSALSRFTNLTYLNLTKNEINYIEDGAFSAQFNLQVLQLGFNKLRNLTEGILRGLGKLQYLYLQANLIETVTPNAFWECPNIENIDLSMNRLQVLDGSTFTSLTKLTTCELYTNPFNCSCELLGFVKWLSVFPN--RTSERMVCDSPAGVSGYSLLSQNPTNPTYRNALHMLSTVCTEDYVTPYISVPP----------DTTTFPPD----STPCGLEDCPSGTEPEEISISPTFL-DLDVKPIMKLKQVSHTNAVITVQIPYPYKKMYILVLYNNSFFTDIQNLKRQKEDIELKNLKPHTDYTYCVASIRNSLRFNHTCLTLSTG-PKNGKERVASNATATHYIMTILGCLFSMVIVLGIVYYCLRKKRQQDEKHKKAG------SLKKNIIELKYGGELEGGTISRMSQKQMMAGESMTRMPYLPSGS-EMEQYKLQDISDTPKMAKGNYMEVRTGEHPDRRDCEMSMAG-NSQGSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGAVSTAEPQLVLISEQPQSKSGFLSPVYKDSYHHS-LQRHHASDAS--PKRPSTATGGSIRSPRPYRSE--GSYKS---ESKYIEKTSPTGETILTITPAAAILRAEAEKIRQYSEHRHSYPDAHQIEELEGP-----------ESRKTSILEPLTRPRARDLAYSQLSPQYHNLSYSSSPEYYCKPSHSIWERFKLHRKRHKDE-EYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: :* : :. .* * * .:.*******:*********************:**.**********:*:*::*::**** ************.********.**********:*:*******:****.**:**********.* ..:******* ********:* *...**:.*:**:.**:*:*** ********::**:.*.* :* :*: *:**. :** **.*. . . * *.:****. :. : ** :.. ** . **. ::* ** . : .*: : :.:* :*:**:::..*.* **:* *:::** * :*** :..*.: :*:*.*.** . *:*****.* . :.******:. . *.* :**************.**:*** ******::*:*:****** ****.******* *:*. :: ::* ::. *::**:****:. ::***** : .:*** :**.*:*****: :**.**:. .. :.*.*************:*********************.***.**.*** ***:** :* .**:* ***:: *. *****: :*: * *.**::.** ****.:*:* * :*: *:***** **. ::***:****::*****:* ***.*******.:* * * **:**********.***.*********.********* *:.* *****::* *:***:: *:********************************:**", "identical_positions": 475, "similar_positions": 196, "identity": "56.35%" }, { "cls_id": "homologset.agr.HGNC:33155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TPD7-1", "uniprot_id": "LR75B_MOUSE", "id": "Q7TPD7-1", "name": "Leucine-rich repeat-containing protein 75B", "aln": "MGARLG------------RRAR----ADAPAAPS---------------------AGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILHRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRKH-----HRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDTRGVELVVLDLSFTELSDELLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDTAKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEP-GGGMAETTAAVSTWGSAATEAGPEPQG----------------CCAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M1Z9-1", "uniprot_id": "A0ABK0M1Z9_RAT", "id": "A0ABK0M1Z9-1", "name": "", "aln": "MGARLG------------RRAR----ADAPAAPS---------------------AGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILYRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRKP-----HRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDSRGVELVVLDLSFTELSDDLLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDATKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEP-GGGMAETTAAVSTWGSAATEAGPEPQG----------------CCAR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2VPJ9-1", "uniprot_id": "LR75B_HUMAN", "id": "Q2VPJ9-1", "name": "Leucine-rich repeat-containing protein 75B", "aln": "MGARLG------------RRAGPEAGSEAGAAAG---------------------CGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLERTLLPDILYRDVAFLNPVDPISHDLLVNLARDLQCPKKDYELWKSSDKICRQLIYHLTPHSKQQQGSSLRQRKTQSCLKSSLQKTLLAGETVDLSGIPLSTQDVQHITRYLSSHGAVLAVLDLSFTGLSDELLHLLLPSLWALPRLTQLLLNGNRLTRATARKLTDAIKDTTKFPALAWVDLGNNVDVASLPQPLLVGLRRRLSQRTSLPTIYEGLDLEP-EGSAAGATTPASTWDSTAAGLGPEPQA----------------CCAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXP5-1", "uniprot_id": "E7EXP5_DANRE", "id": "E7EXP5-1", "name": "", "aln": "MGSKLTRQSSLDSQASFFRRGRQDHEERRTGGRG-DFLFSSLMLRSDKLPGVLRRSSPCPYVRRVAWVREIQTLLKEQKLEQAIDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLNLARDLQCPKREADALKSSEKICRQLIYHLTPHSKWSR-QNVPRRKTQACLKTTLKKKLAN-DTVDLSGIPLSGRDLHRVAYYLQNNGSSVTAVDISFTELHDESLRLLLPYLGVLPKLSTLAINGNRLTVAILKDLIEVVKDPQKFPCLAWVDLGNNVDIFTVPQPLLVALRRRFGMRSSLPTIYEYSEGQGSSYCLETSVEEISVFEEEEEDEEDELEDHLVLEAWSVEEKNTLHFCER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QJF5-1", "uniprot_id": "F1QJF5_DANRE", "id": "F1QJF5-1", "name": "", "aln": "MGSRLSRQNSLDNEN-FSRRRRKHLDSTGESDRGGDFLFTSLMLRSDKLPGMLRRSNHSPYVRRVAWIREMQKLLRERKIEEATDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLSLARDMQCPKKDLETLKSSDKICRQLIYHLTPHSKWLR-KSMTRRKAQACLKTTLQKKLCS-DSVDLSGIPLSTRDIRHVAYYLQTSGGAVISVDLSFTELRDEGLRLLLPFLGALPKLTTLALNGNRLTLGILKDLSEAFKESKRFSCLAWIDLGNNVDIFTMPQPLLVALRRRCSLKSSLPTIYEYTEGQPYCYRMESSIEEPSHYEEEEDEDYDEDLEPWSIGEQKSSGSFTLHHCER", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::* ** . . .. .** *** *:**:*. *:*:: *.* ::*:***:***** . * ***:::.:*** ******:**:.****:****:: : ***:*************** :**:*:.**::*:*.* ::********* :*::::: **.. * : :*:*** * *: *:**** * .**:*: * :****** . :.* :..*:. :*. ***:*******: ::******.**** . ::******* : : : * : . * * *", "identical_positions": 145, "similar_positions": 82, "identity": "39.73%" }, { "cls_id": "homologset.agr.HGNC:33156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALY3-1", "uniprot_id": "A0A8I6ALY3_RAT", "id": "A0A8I6ALY3-1", "name": "", "aln": "MEGKGKVKRPKAYMVRHNR--RRRRLNPIPFPELFDGDMDKLPEFIVQTGSYMLVDHKIFDTDELKVTFLITRLKGRALQWVIPYIKIESPLLNDYIGFLNEMKRVFGWEEDEDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q17RB0-1", "uniprot_id": "RTL8B_HUMAN", "id": "Q17RB0-1", "name": "Retrotransposon Gag-like protein 8B", "aln": "MEG--RVQLMKALLARPLRPAARRWRNPIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIKKESPLLSDYRGFLAEMKRVFGWEEDEDF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :*: ** :.* * ** ******* **** *:********.***:**.: *..* **********.* ********** *****.** *** **************", "identical_positions": 82, "similar_positions": 13, "identity": "71.3%" }, { "cls_id": "homologset.agr.HGNC:33159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32Q92-1", "uniprot_id": "ACOT6_MOUSE", "id": "Q32Q92-1", "name": "Acyl-coenzyme A thioesterase 6", "aln": "-----------------------MAATLSVEPAGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGMLFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQIPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGKGQFPGIIDLYGSIGGLCEHRASLLAGHGFAVLALAYFQFEDLPENLSDVRLEYFEEALALMLRHPQVKGPNIGLIGVSKGADLCLSMAAFLKDNITATVLINACVANTLVPLYYKDLFVPELGCDQTK---NKSGLMDLRDMWNNPLEEPNHQSLIPLEKAQGPFLFLVGMDDHNWKSDVYARIACERLQAHGKDRPQIIYYPETGHCIEPPYFPPPIATVHFVLGEAVFNGGKPRAQSRAQLDAWQRIQTFFQKYLNGEKPARHSKL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3I5F7-1", "uniprot_id": "ACOT6_HUMAN", "id": "Q3I5F7-1", "name": "Acyl-coenzyme A thioesterase 6", "aln": "-----------------------MAATLILEPAGRCCWDEPLRIAVRGLAPEQPVTLRTSLRDEEGALFRAHARYRADARDELDLERAPALGGSFAGLQPMGLLWALEPEKALVRLVKRDVRTPFAVELEVLDGHDTEPGRLLCLAQNKRDFLRPGVRREPVRAGPVRAALFLPPDEGPFPGIIDLFGSSRGLCEYRASLLAGHGFAVLALAYFRFEDLPEDLNDVHLEYFEEAVDFMLQHPKVKGPSIALLGFSKGGDLCLSMASFLKG-ITATVLINACVANTVAPLHYKDMIIPKLVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDAWQQIQTFFHKHLNGKKSVKHSKI----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T759-1", "uniprot_id": "A0A8N7T759_DANRE", "id": "A0A8N7T759-1", "name": "", "aln": "MYATLKCALKPFARNTLAKMHYSSGVSIRLLPSYKCSFEDPVHVTVSGLNPHQRVDLRSKITDEGGRDFKALATYQADDSGQIDLKRDSSLGGSFTGVEPMGLYWALKADTISCKFKLKDVTRPALVDIEVVSDD-----KVLAKVTNERHCLTDGVRRRPLNEDRIRGTLFMPPGKGPFPGILDTYILRGGHFELRAALLAKRGFAVLALAYQNYQDLPKSSDKFHLEYFEEGIDFLRQQPEVKGQKIGLLSISKSGDLALSMSTFLPD-IAATVWINGCNANSVVPLYYKDMYIPPLTLDFKKKKITPLGLVDMLDVVKDPMSKEGLPSVIPIERAPGRFMFIASEANMNWRSAYHAKLACDRLKAHGKKNYELVKYEKAGHFIEVPYMPFCFANFHSVLKQPVLFGGEPKCHSEAQVDAWPRIINFFKKHLATADYNLSPMLEENIHEMSQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NZE7-1", "uniprot_id": "A0A8M1NZE7_DANRE", "id": "A0A8M1NZE7-1", "name": "", "aln": "MYAALKFAFMPFAR-SLAKVHYSSGVSIKLLPSYKCSFEDPVHVMVSGLNPHQRVNLRSKITDEGGRDFKASAIYLADDNGQIDLKRDSSAGGSFSGVEPMGLFWALKADLLSCKFKLKDVTRPALVDIEVVGEDE----KVLAKVTNERHCLSEGVRRSLVTEGRIRGTLFMPTGNGPFPGILDTYILKGGPFELRAALLAKRGFAVLALAYQNYQDLPKKADKFHLEYFEEGLDFLRRQPEVKGQKIGLLSISKSGDLALSMSTFLPD-ITAAVWINGCNANSLIPLYYKDMYIPPLTLDFKKKKMTALGLVDMLEVVNDPMSKEGLPTVIPIERASASFMFIASEADMNWRSVYHAKLACDRLKAHGKNNYELVKYEKAGHFIEVPYMPFCLAAFHGVLEQPVLFGGEPKAHSEAQVDAWQRIIIFFKRTLGS-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: : *: :..:::*: : * ** *.* * **: : ** * *:* * * ** .::** * .: ****:*::**** **::.: :: :** * *::**:. . : *. . ::*. : **** : . :*.:**:*..:* ****:* : * * **:*** :********* .::***:. ...:******.: :: ::*:*** .*.*:..**..**.***::** . *:*:* **.* **:: **:***: :* * * * . *:: : : .:*:.: . :::*:*:* *:*:.. : .*:* :*::*.:**:****.. ::: * ::** *: **:* * .* ** :.:: **:*:.:*.**:*** :* **:: * ", "identical_positions": 153, "similar_positions": 145, "identity": "33.63%" }, { "cls_id": "homologset.agr.HGNC:3316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9V2-1", "uniprot_id": "G3V9V2_RAT", "id": "G3V9V2-1", "name": "", "aln": "-------------MAAVVQQNDLVFDFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNGYAGLACVEEPNDMITESSLDVAEEEIIEDDDDDITLTVEASCHNGDETIETIGAAEALLNMDSPGP-VLDEKRINNNIFSSSEDD-IVAPITHVSVTLDGIPEVMETQQVQESN--------------ADSPGASSPEQPKRKKGASLTCLGRRKTKPPRPDSPATTPNISVKKKSK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEGPSSSTESSDQSLSSTTTSSRNQAN--------------------------RTRMSSSPGIKGGATTILKPGNPKVAKPKDTVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAIPE-----EATITSTMQEEAAGSSVQG--IRTIQASTQVPVVVSPGNQQ--LHTVTLQTVPLTT----------------VIASTDPSSGAGP-------------------------------------------------------------QKFILQAIPSSQPMT---VLKEN-VLLQSQKPGSPPSIVFSPT-------------PVQQVLTGS--VQSLGNGAVSMASPPNFSATAPVVTFS-RSSQLAAHPPGTVITSVIKAQETKTPKAEVEKK-AEGHLNGDPEEIEQQPQPYVMVVSSS--NGFSSQVAITQNE--------------------LLEPSSF----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60775-1", "uniprot_id": "ELF1_MOUSE", "id": "Q60775-1", "name": "ETS-related transcription factor Elf-1", "aln": "-------------MAAVVQQNDLVFEFASNGMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAAEALLNIDSPSPPVLDEKQINNNIFSSSEDD-IVAPITHVSVTLDGIPEVMETQQVQETN--------------ADSPGASSPEQRKRKKG--------RKTKPPRPDSPTTTPNISVKKKNK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDQSLSSTTASSRNQAN--------------------------RSRVSSSPGIKGGAATILKPGNSKAANPKDPVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAVPE-----EATIASTMQEEAANSSVPS--IRTIQASTQVPVVVSPGNQQ--LHTVT---VPLTT----------------VIASIDPSSGAGS-------------------------------------------------------------QKFILQTIPSSQPMT---VLKEN-VMLQSQKPGSP-SIVLSPT-------------QVQQVLTSN--VQSICNGAGSVASAPSFSATTPVVTFS-RSSQLVAHPPGTVITSVIKAQETKTLKQEVEKK-AEDDLNEDAEKSAQQPQPYVMVLSSS--NGFSSQVAVKQNE--------------------LLEPNSF----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32519-1", "uniprot_id": "ELF1_HUMAN", "id": "P32519-1", "name": "ETS-related transcription factor Elf-1", "aln": "-------------MAAVVQQNDLVFEFASNVMEDERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGP-MLDEKRINNNIFSSPEDDMVVAPVTHVSVTLDGIPEVMETQQVQEKY--------------ADSPGASSPEQPKRKKG--------RKTKPPRPDSPATTPNISVKKKNK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTS--------------------------RSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEG----EAARTSTMQDETLNSSVQS--IRTIQAPTQVPVVVSPRNQQ--LHTVTLQTVPLTT----------------VIASTDPSAGTGS-------------------------------------------------------------QKFILQAIPSSQPMT---VLKEN-VMLQSQKAGSPPSIVLGPA-------------QVQQVLTSN--VQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSS--NGFTSQVAMKQNE--------------------LLEPNSF----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2K0-1", "uniprot_id": "A0A8M6Z2K0_DANRE", "id": "A0A8M6Z2K0-1", "name": "", "aln": "-------------MTTVVQANELVFEFASNGMDEINQLDDPSVFPAVIVEQVPAADLMQVYSGLEADEVTNGIMVDAIQDVVEENMMG----DVGLSVETPVSGGEDNMETIEAAEALLNMESPNN-ILDEKRMIHTYGNILETD-----LSYISLRPEHLSNGMDVAHDDETSS-------------LDEVPQKNFSKPARKTK-------VRKPRPARPCSPITNPSLPLKKKSK-----------------EGKGNTIYLWEFLLALLQDKNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPTDLVIIDEDDGQGDDGGAGYGGHRAAPHGRVGRG--------------------------SSRSQGRNTQVKTVKREMSPG-LNSRNGKQAEQLLQTVHVLQPNQGAAVPAQTHSVRTINMPGSVPMVLTSG--AQGGGPMTLQTLPLSSVLTNGDSSTHASPPRVILHTVPSTSPGGKDVLTIQTASLTTDSLH---------SQQLLVSTLSSSSGGV-------------------------------------------------------------ISTTPQQTASLNGITRLVTLNANGQPVVAQQPGTVIATVLKPSEYQS--------LQVKEEISDPQYFQSLVNNSPSFASFCKDEIAEGMAEMS--YRTVIINTAGQELSQSLNGHSQLASSPSEGLTPVEELEVRGEVALHPEPEAKELLESSQGLQELPVTMQIPASH--------------------FIQVKAEPTET------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11536-1", "uniprot_id": "E74EB_DROME", "id": "P11536-1", "name": "Ecdysone-induced protein 74EF isoform B", "aln": "MIMVQHLVAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPGAIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKVLYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKSLMKRYYTEIPIVKQSTSPAPQQQLQQQHHLQQQQQQQPHNGSTFAGATALLHIKTEQNTLLTPLQLQQQQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQNNAANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEIDCNGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .** :*. .. . .. :: .: . :..* : : . . . : . : : :.. . : :* .: :*::.*. : *. : . . : :* : : : . . . .. .: . ** : *. : *.: :::.: :.. :: * ** *: .* :. . . . :.***: *: . .: : .: . * : *: .. :*. .:: :.:. . : . : . . ... : : ::. : * : . . : * .. : . : .. . :.. . . . .. * * : . *:. * . * . : : *. : *: : : * . : . : : .:* . : : * ..* : . : . : : * . . : . ::: .: ", "identical_positions": 39, "similar_positions": 178, "identity": "4.42%" }, { "cls_id": "homologset.agr.HGNC:33160", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHW6-1", "uniprot_id": "D3ZHW6_RAT", "id": "D3ZHW6-1", "name": "", "aln": "MKVTFSVAVLVLAISVWTSFAVDFFLPMGFHTTEELLKETKALCVKNVQMCWILTYFKLSEPICGSNQVTYNGECHLCSEILFEDRTIIKVHDGPCETSSD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q09TK9-1", "uniprot_id": "ISK8_MOUSE", "id": "Q09TK9-1", "name": "Serine protease inhibitor Kazal-type 8", "aln": "MKVIFSVAVLVLASSVWTSLAVDFILPMNFHMTGELLQKTKALCIKNIQLCWILSYFKVSEPICGSNQVTYEGECHLCSGILYEDRTVIKVHDGPCEHSSDESEH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7L1-1", "uniprot_id": "ISK8_HUMAN", "id": "P0C7L1-1", "name": "Serine protease inhibitor Kazal-type 8", "aln": "MKGICSDAILVLATSMWMAFAIDFPLPM--ASERGQLDKTIVECLKNVNKCWFLSYIKPSEPICGSDQVTYSSDCHLCSKILFEGLNITKLYDGQCENS------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *:**** *:* ::*:** *** *.:* . *:**:: **:*:*:* *******:****..:***** **:*. .: *::** ** * ", "identical_positions": 51, "similar_positions": 24, "identity": "48.57%" }, { "cls_id": "homologset.agr.HGNC:33164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NXT2-1", "uniprot_id": "H3C_HUMAN", "id": "Q6NXT2-1", "name": "Histone H3.3C", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVK-PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84245-1", "uniprot_id": "H33_RAT", "id": "P84245-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PI20-1", "uniprot_id": "H33_DANRE", "id": "Q6PI20-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "C0HL66-1", "uniprot_id": "H33A_DROME", "id": "C0HL66-1", "name": "Histone H3.3A", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HL67-1", "uniprot_id": "H33B_DROME", "id": "C0HL67-1", "name": "Histone H3.3B", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P84244-1", "uniprot_id": "H33_MOUSE", "id": "P84244-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61830-1", "uniprot_id": "H3_YEAST", "id": "P61830-1", "name": "Histone H3", "aln": "MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:******:*** *** ****:***********:************************:*******:*:*****: *****.*:*****.********* ***:****:****:", "identical_positions": 117, "similar_positions": 14, "identity": "86.03%" }, { "cls_id": "homologset.agr.HGNC:33169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10083-1", "uniprot_id": "AST5_DROME", "id": "P10083-1", "name": "Achaete-scute complex protein T5", "aln": "------------------------------------------------------MALGSENHSVFNDDEES------SS---AFNG------------PSVIRRNARERNRVKQVNNGFSQLRQHIPAAVIADLSNGRRGIGPGANKKLSKVSTLKMAVEYIRRLQKVLHEND-------QQKQKQLHLQQQHLHFQQQQQHQHLY--AWH--------------QELQLQSPTGSTSSCNSISSYCKPATSTIPGATP-----------------------------------------------PNNFHTKLEASFEDYRNNSCSS-GTE----DEDILDYISLWQDDL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09774-1", "uniprot_id": "AST3_DROME", "id": "P09774-1", "name": "Achaete-scute complex protein T3", "aln": "-------------MTSICSSKFQQQHYQLTNSNIFLLQHQHHHQTQQHQLIAPKIPLGTSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPYGE---QLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGR----GSSKKLSKVDTLRIAVEYIRGLQDMLDDGT-------ASSTRHIYNSADESSNDGSSYNDYND--SLD--------------SSQQFL--TGATQSAQSHSYHSASPTPSYSGSEI-----------------------------------------------SGGGYIKQELQEQDLKFDSFDS-FSDEQPDDEELLDYISSWQEQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10084-1", "uniprot_id": "AST4_DROME", "id": "P10084-1", "name": "Achaete-scute complex protein T4", "aln": "MKNNNNTTKSTTMSSSVLSTNETFPTTINSATKIFRYQHIMPAPSPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPYNVDQSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGR---GPHKKISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNAVTQLQLCLDESSSHSSSSSTCSS--SGHNTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCVSTSKNQQTCHSPTSSFNSSMSFDSGTYEGVPQQISTHLDRLDHLDNELHTHSQLQLKFEPYEHFQLDEEDCTPDDEEILDYISLWQEQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1LUI6-1", "uniprot_id": "F1LUI6_RAT", "id": "F1LUI6-1", "name": "", "aln": "--------MNSNFCRALVDR---GSPGGIQLGVVAPAGPTPLAATEPLGNVPFLLYPGHSEPSYYDAYTGVFPYVPFPGAFGVYDYPFEP--------AFIQKRNERERQRVKCVNEGYARLRGHLPGALA--------------EKRLSKVETLRAAIRYIKYLQELLSAAP------------------DGAPPTAT------------------------------------SPPPAHAGHGNALQPPSLVAESS-------------------------------------------------GSSFSPSPFLESEEPSL---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QWB7-1", "uniprot_id": "ASCL5_MOUSE", "id": "M0QWB7-1", "name": "Achaete-scute homolog 5", "aln": "--------MNSNFCRALVDR---GPPGGMQLGVVAPAGQTPLAATEPLSNVPFLLYPGHSEPPYYDAYTGVFPYVPFPGAFGVYDYPFEP--------AFIQKRNERERQRVKCVNEGYARLRGHLPGALT--------------EKRLSKVETLRAAIRYIKYLQELLSATP------------------DGAPPPAT------------------------------------SPPPAHTGHSNVPQPSSLVAESS-------------------------------------------------GSPFSSSPFLESEEPSL---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU5-1", "uniprot_id": "ASCL5_HUMAN", "id": "Q7RTU5-1", "name": "Achaete-scute homolog 5", "aln": "--------MNNNFCRALVDRRPLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAFGVYEYPFEP--------AFIQKRNERERQRVKCVNEGYARLRGHLPGALA--------------EKRLSKVETLRAAIRYIKYLQELLSSAP------------------DGSTPPASRGLPGTGPCP----------------------APPATPRPDRPGDGEARAPSSLVPESSE------------------------------------------------SSCFSPSPFLESEESWH---------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . : :** ***:*** **:.: .** *:* :: *::***.**: *:.**: **.:: : . . . . . . . . ", "identical_positions": 26, "similar_positions": 32, "identity": "7.41%" }, { "cls_id": "homologset.agr.HGNC:3317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ACZ4-1", "uniprot_id": "A0A8I6ACZ4_RAT", "id": "A0A8I6ACZ4-1", "name": "", "aln": "---------MDAAAP----------------------------------GATRQNAPGLLPRPSRSS--------------------------AGVTVLRPLPVEASVHSSNAHCTDKT-------IEAAEALLHMESPTCLRDSRS----------------------------------------PEFIHAAMRPDVITETVVEVS---TEESEPMDASPIPTSPD--SHEPMKKKKVGRKPKTQQSPVSNGSPELGVKKKAREGKGNTTYLWEFLLDLLQD------KNTCPRYIKWTQREKGIFKLVDS-------KAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEG----------QRLVYQFKDMPKN---------IVVIDDDK---------------------SETCPEDLAAAADDKSLERVSLSAESLLKAATAVRGGKNSSPMNCSRAEKGVTRVVNITSPAHD---ASSRC---------------PTTTAPVSAAAAPRTVRVAMQVPVVMT-SLGQKISTVAVQSVN---------------AGT--PLITST-SPATASSPKVVIQTVPTVMPASAENG----DRITMQPAKIITIPATQLAQCQLQTKSNLTGSGSISLVGTPLAVRALTPVSIAHGTPVMRLSVPAQQASGQTPPRVISAVIKGPEV-KSE--AKKQEHDVKTLQLVEEKGADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHC9-1", "uniprot_id": "ELF2_MOUSE", "id": "Q9JHC9-1", "name": "ETS-related transcription factor Elf-2", "aln": "---------MASAVVDSGGSALELPSDGGENQE---------------GGDTGPDCPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENSETVEASVHSSNAHCTDKT-------IEAAEALLHMESPTCLRDSRSPV----------------------------EVFVPPCISTPEFIHAAMRPDVITETVVEVS---TEESEPMDASPIPTSPD--SHEPMKKKKVGRKPKTQQSPVSNGSPELGIKKKAREGKGNTTYLWEFLLDLLQD------KNTCPRYIKWTQREKGIFKLVDS-------KAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEG----------QRLVYQFKDMPKN---------IVVIDDDK---------------------SETCPEDLAAAADDKSLERVSLSAESLLKAATAVRGGKNSSPLNCSRAEKGVARVVNITSPTHD---GSSRS---------------PTTTAPVSAAAAPRTVRVAMQVPVVMT-SLGQKISAVAVQSVN---------------AGTGSPLITST-SPASASSPKVVIQTVPTVMPASTENG----DRITMQPAKIITIPATQLAQCQLQAKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSVPAQQASGQTPPRVISALLKGPEG-KSE--AKKQEHDVKTLQLVEEKGADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15723-5", "uniprot_id": "ELF2_HUMAN", "id": "Q15723-5", "name": "ETS-related transcription factor Elf-2", "aln": "---------MTSAVVDSGGTILELSSNGVENQE---------------ESEKVSEYPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENVETVEASVHSSNAHCTDKT-------IEAAEALLHMESPTCLRDSRSPV----------------------------EVFVPPCVSTPEFIHAAMRPDVITETVVEVS---TEESEPMDTSPIPTSPD--SHEPMKKKKVGRKPKTQQSPISNGSPELGIKKKPREGKGNTTYLWEFLLDLLQD------KNTCPRYIKWTQREKGIFKLVDS-------KAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEG----------QRLVYQFKDMPKN---------IVVIDDDK---------------------SETCNEDLAGTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINCSRAEKGVARVVNITSPGHD---ASSRS---------------PTTTASVSATAAPRTVRVAMQVPVVMT-SLGQKISTVAVQSVN---------------AGA--PLITST-SPTTATSPKVVIQTIPTVMPASTENG----DKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSMPTQQASGQTPPRVISAVIKGPEV-KSEAVAKKQEHDVKTLQLVEEKPADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QIV0-1", "uniprot_id": "A0A2R8QIV0_DANRE", "id": "A0A2R8QIV0-1", "name": "", "aln": "---------MTSVVLVDSGGAVVEYVTAVDDHLPEEGGVYEVEGEMEGEVEGDVEYPAVIVEPVPSARMEQGFAAQVLVYDDETYLMQGVAEEQEVETEVLETVEASVHG--VQCSDKT-------IEAAEALLHMDSPSSLRGDRSP-----------------------------EVFVPPCVNTSEFLHAAMRPDVLTETVVEVS---TEDMEPMEVVTVIQEPEMLDTEPSKRRKSGRKPKPHH--ISNGSPDMGIKKKSREGKG-STYLWEFLLDLLQD------KNTCPRYIKWTQREKGIFKLVDS-------KAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEG----------QRLVYQFKEMPKD---------IVVIDDDK---------------------CDPG-DDVIG---EKTYERVPPSSDTLLTDLSKTPTILRAADRTVLHPGSPKAKAALTATPVQRTVMVSTAD---------------PSHATIISNANAPRTVRVAMQVPVVMTNSLGQKISTVAVQSTN---------------PSLLTTAPTNTGSPTGTNAPKVLIQTMPTMVPATAENG----DKITVQLAKIITIPATQLTQCQLQAKPG-TPTG-INLMGAPLTVRALTPMSVAPGTQVVRLAVPAQQSPVQAKTQVPVSIQTQTRIPISVQTASTVQSVPLQIQIQQSQLSPKEKTTESKPDITVLDNPTLKVPEEASNPQSEAES-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11536-1", "uniprot_id": "E74EB_DROME", "id": "P11536-1", "name": "Ecdysone-induced protein 74EF isoform B", "aln": "MIMVQHLVAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPGAIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKVLYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKS-LMKRYYTEIPIVKQSTSPAPQQQLQQQHHLQQQQQQQPHNGSTFAGATALLHIKTEQNTLLTPLQLQQQQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQNNAANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEIDCNGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * .: . : :. . .* . * :*::: :**: : . : :. *:. ** .*: :** * : :: .: . . : :: . : : :.:...:: . : .* :: *** . .:.. ::*. :. .:* :* :* ::* : . *:. *** : *: : . ::* * :: *:: :: *. :: . . . .: : :. . .** .. . . . : *: .: :: : : *. :. . ::. ..: .* *: :: :::. .. . .. .* . .. . ** .*::.: : : :* :* * * . : *: : . :* * :: :: .: .. : * . : . :. :. : * : . : ", "identical_positions": 51, "similar_positions": 174, "identity": "5.77%" }, { "cls_id": "homologset.agr.HGNC:33179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UTA9-1", "uniprot_id": "I4E1B_MOUSE", "id": "Q3UTA9-1", "name": "Eukaryotic translation initiation factor 4E type 1B", "aln": "---------------------------------------------------------------MNKVEGGGHKEEVVVKEKE-------------------VVKEKPSEATAEGVQAGEAKDLPGSLKTQRRKAHREHPPEVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKLHPLQYRWVLWFFK--NDRSRAWQDNLQLVTKFNTVEDFWAVYSHIKLASKLSSGCDYALFKEGILPMWEDNRNKQGGRWLLSIDKQLRHFELDRLWLETLLCLVGNCFEEYSREVCGAVVNIRTKRDKIALWTSEAEDKAGVMQIGQIYKERLGISTKTIIGYQAHADTAAKSNNLAN-KFVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A3E5-1", "uniprot_id": "A0A8I6A3E5_RAT", "id": "A0A8I6A3E5-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "MLVRPLLLLVLYSSLSCQEVAPDANFPPPSQLQSQCANCQTDYRTQERTLEASLQGRRELEAQMSKAEGEGQEEEEEEEEEEEKEEEEEEEEEEKEEEEEEEVKEKPSEATAEGLQG-EARDLPGSLKTVKQKAQREHPTKLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RELHPLQFRWVLWFFK--NDRSRAWQDNLQLVTKFDTVEDFWATYRHVKLASKLSCGCDYALFKEGIQPMWEDSRNKRGGRWLLSLAKQQRHMELDRLWLETLLCLLGESFEEYSGEVCGAVVNIRTKGDKIALWTSEAENKAGVMHIGHIYKERLGLSTKTIIGYQAHADTAAKSNSLAKNKFVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NMX2-1", "uniprot_id": "I4E1B_HUMAN", "id": "A6NMX2-1", "name": "Eukaryotic translation initiation factor 4E type 1B", "aln": "----------------------------------------------------------MLAVEVSEAEGGIREWEEEEKEEE------------------------AAERTPTGEKS---PNSPRTLLSLRGKARTGGPMEVK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LELHPLQNRWALWFFK--NDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PW28-1", "uniprot_id": "IF4EB_DANRE", "id": "Q9PW28-1", "name": "Eukaryotic translation initiation factor 4E-1B", "aln": "---------------------------------------------------------------MASCAVQLIDKVPKKKVEK--------------------------------------------------KKFEPNILKEP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CMKHPLQNRWGLWFYK--NDKSKMWQDNLRLITKFDTVEDFWGLYNNIQLPSKLSSGCDYSMFKDGIEPMWEDRSNKCGGRWLITLAKQHRHTELDHFWLETLLCLIGEGFSSFSRDICGSVINIRAKGDKIALWTSNAENCETVTYIGRKYKESLGLPQKLVIGYQAHADTATKSNSITKNKFVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48598-1", "uniprot_id": "IF4E_DROME", "id": "P48598-1", "name": "Eukaryotic translation initiation factor 4E1", "aln": "--------------------------------------------------------MQSDFHRMKNFANPKSMFKTSAPSTE-----------------------QGRPEP---------PTSAAAPAEAKDVKPKEDPQETGEPAGNTATT----------------------------------------------------------------------------------------------------------------------------------------------------------------TAPAGDDAVRTEHLYKHPLMNVWTLWYLE--NDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKS-SKTDLDNLWLDVLLCLIGEAFDH-SDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRY0-1", "uniprot_id": "Q9VRY0_DROME", "id": "Q9VRY0-1", "name": "eIF-4F 25 kDa subunit", "aln": "-----------------------------------------------------------------MLTTQQTEFKMMDNGTE-----------------------TLADSP---------SSSSEDLKTLSDMDIRKPVTEIVDLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKHPLENTWTLWYLE--NDRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRG-SKAELDKLWLDVLLILIGEAFEN-TEEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLLVLPP-HQLQYQLHKDTMCKQGSVIKAVYCV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5B3-1", "uniprot_id": "Q9W5B3_DROME", "id": "Q9W5B3-1", "name": "eIF-4F 25 kDa subunit", "aln": "-------------------------------------------------------MLPNSFYRMRDFANPRTMFKSCANNNE-----------------------YPTQGPQKVESPTDVTQPAAAPQSTEDTQPEKTQEPMNDPNKTSPSEPQKRGKGNRKGKKNQKNAPRTPSQTSKSSRSNNPGKDGKSTGNDDNEKGKGQGKQMVQQKENSPEQEQSTSAQYRKNVLDKDLQDKKLIEKNMQGKIITQENLLGQKVLMRLSEQKLLSLRLEPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLE--NDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLTKS-AKMALDSFWMDAMLCLIGEACKH-SDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSB6-1", "uniprot_id": "Q9VSB6_DROME", "id": "Q9VSB6-1", "name": "eIF-4F 25 kDa subunit", "aln": "-----------------------------------------------------------------MASAQVQSFDIMKQQDQ-----------------------QHQLNS------IHKHHHHHEGVPLESNSPEPIDEEIYQVE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKHPLEHVWTLWYLE--NDRTKHWKDMLNEITEIDSVETFWSLYHTIKTPAELKIGCDYSVFKKGIKPMWEDEANIKGGRWLVTVSKS-AKAELDQIWLDILLLMVGQNFEY-SDEICGAVINIRNKSNKISVWTANGSNEMAILEIGQKLKILLHLQS-HSLQYQLHSDAMSKFNSGVKSVYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSG1-1", "uniprot_id": "Q9VSG1_DROME", "id": "Q9VSG1-1", "name": "eIF-4F 25 kDa subunit", "aln": "-------------------------------------------------------MVYTGYVSNGLQNAEETAWVPYGDPND-----------------------WSHGLA---------VYDGLELMSGNEEELQPSLNRVMKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDYDLAMKHPLEHTWTLWHLE--NDRTKRWAEMLVDVTSFNTVEDFFSVYYFVKPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLDKA-SRTYIDKMWHDLLLCMIGECFQH-SDEICGVVINVRNKANKLSLWTKDSRNVEAILSIGRQIKELLHLGI-MEIQYQVHKDAMVNHGPNVNAIYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAR1-1", "uniprot_id": "Q9VAR1_DROME", "id": "Q9VAR1-1", "name": "eIF-4F 25 kDa subunit", "aln": "----------------------------------------------------------------------MENLRQTKESSE-----------------------FKMGTS----------LDNNKLASLGATN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHRLQNTWTLWGVK--YDPEISWEDMLKEIDSFNTVEDFWNLYFRIDTPSKLNRGCDYMLFKKGIRPMWEDPPNKGGGRWTYKVDKR-STAELDKTWLDVLLCMIGEACDH-CDQICGAFVRIRKNINKISVWTKADAGDECNEQC--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07260-1", "uniprot_id": "IF4E_YEAST", "id": "P07260-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "----------------------------------------------------------------MSVEEVSKKFEENVSVDD----------------------------------------TTATPKTVLSDSAHFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLRGK--GADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTK-SEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHSSANGRHPQPSITL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * * ** : * * : : ..: ** *: : . .: ** :*:..: * *** * **:* : :* * :* ::*: . :: * .: :* :*:::*. . ", "identical_positions": 29, "similar_positions": 36, "identity": "5.68%" }, { "cls_id": "homologset.agr.HGNC:3318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V7E1-1", "uniprot_id": "ELF3_RAT", "id": "Q4V7E1-1", "name": "ETS-related transcription factor Elf-3", "aln": "MAATCEISNVFSNYFNAMYSSEDPTLAPAP-LTTFGTEDFVLTLNNQHMSPEGPVGCVGPQTRSQRDRTEPPAVLHLAEKASWTGERPQFWSKTQVLDWISYQVEKNKYDASSIDFSRCDMDGATLCNCALEELRLVFGP-LGDQLHAQLRDLTSSSSDELSWIIELLEKDGMTFQEGLGDSGPFDQGS---PFAQELLDDGRQASPYYGSSYG-----PGAPSPGSSDFSTSGTDTPQSSHS------SDSGGSDVDLDLTDSKVFPRDGFPDYKKGEPKHGKRKRGRPRKL--SKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVGESQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UPW2-1", "uniprot_id": "ELF3_MOUSE", "id": "Q3UPW2-1", "name": "ETS-related transcription factor Elf-3", "aln": "MAATCEISNVFSNYFNAMYSSEDPTLAPAP-PTTFGTEDLVLTLNNQQMTLEGP----GPQTRSQRDRTDPLAVLHLAEKASWTSERPQFWSKTQVLEWISYQVEKNKYDASSIDFSRCDMDGATLCSCALEELRLVFGP-LGDQLHAQLRDLTSNSSDELSWIIELLEKDGMSFQESLGDSGPFDQGS---PFAQELLDDGRQASPYYCSTYG-----PGAPSPGSSDVSTARTATPQSSHA------SDSGGSDVDLDLTESKVFPRDGFPDYKKGEPKHGKRKRGRPRKL--SKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVGESRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78545-1", "uniprot_id": "ELF3_HUMAN", "id": "P78545-1", "name": "ETS-related transcription factor Elf-3", "aln": "MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGT------------------------EKASWLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGP-LGDQLHAQLRDLTSSSSDELSWIIELLEKDGMAFQEAL-DPGPFDQGS---PFAQELLDDGQQASPYHPGSCG-----AGAPSPGSSDVSTAGTGASRSSHS------SDSGGSDVDLDPTDGKLFPSDGFRDCKKGDPKHGKRKRGRPRKL--SKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVLQSRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB26-1", "uniprot_id": "E7FB26_DANRE", "id": "E7FB26-1", "name": "", "aln": "-MASSELSLILNNANANLYPEPQASLLSMCRPPHLS----EITFNSNST------------------------------LGSWDQVNPQMWSRQNVLEWIGFHVEESRFDAGLLNLNYCTMDGLTLCATSKEALMSMFGPELGNLLHHSLESLKARYVNDLSENTVLSESEFELLDNILQNSFPSMHGPGLGPLLETVVVQSTIPTDNSDAKYSYFDEYTSQLTPESDHGYDSLTESFQSSHAGSFLNPSSPESNSSDSDPEYSETPYSISSKNFSKQEPEKTKRGRGRPPKLRDSDGFDHFIQSKKSKHAPRGTHLWEFIRDILIHPEQNQGLMKWEDRRDGVFKFLKSEAVAQLWGQKKKNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSTGWRIEETGY---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.*:* ::.* :*.. :.:* . . :. :*:.. .** .**:**: :**:**.::**:.::**. :::. * *** *** : * * :*** **: ** .*..*.: ::** * *.: ::: * :. * :*. *: : :: :. .: .. . .. :* *.. : * : :***: *.. ... * * .: . : .* :*:: ** **** ** *. : . ::.************************ *:******:*::******:***************.***********************************:**: **. ", "identical_positions": 159, "similar_positions": 105, "identity": "38.5%" }, { "cls_id": "homologset.agr.HGNC:33185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NSW5-1", "uniprot_id": "DBX1_RAT", "id": "Q5NSW5-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQS---------AFSGHSSFLVEDLIRISRP----------PTYLPRSIPTASLSPPRQEAPTALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA---------------PRRETSPALLQSPPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSD--------------------------------------VGQKGPGDEEED----------------------------------SPGASLAYHAPPDP--------------------------------------------------------RHL----LEGPLPASPAHSSSPGKPSD---------------------FSDSDEDEEGEEDEEITVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52950-1", "uniprot_id": "DBX1_MOUSE", "id": "P52950-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQS---------AFSGHSSFLVEDLIRISRP----------PTYLSRSIPAASLSPPSQEAPAALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA---------------PRRETSPALLQSPPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSD--------------------------------------VGQKGPGDEEED----------------------------------NPGARLAYHAPADP--------------------------------------------------------RHL----LEGPLPASPAHSSSPGKPSD---------------------FSDSDEDEEGEEDEEITVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMT0-1", "uniprot_id": "DBX1_HUMAN", "id": "A6NMT0-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQS---------AFSGHSSFLVEDLIRISRP----------PAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRG-----------GSPPTAFSPASETTFLKFGVNAILSSG---------------PRTETSPALLQSVPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSD--------------------------------------VGQKGPGNEEEEEGP------------------------------GSPSHRLAYHASSDP--------------------------------------------------------QHLRDPRLPGPLPPSPAHSSSPGKPSD---------------------FSDSEEEEEGEEQEEITVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTU1-1", "uniprot_id": "DBX1A_DANRE", "id": "Q9PTU1-1", "name": "Homeobox protein DBX1-A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMIPSVIAP-------------------------PAIYSAFMRP------AASLHS---------PFPAHPSFLVEDLLRINRP----------SGFLSQTAHSPCASPPNSTPLSIPDNCRILDRVSPGITEKHGP----------CSPKTPVS-SKDPTYLKFGVSAILAPS---------------PKKATSPPSVHSIHPKGFSVPYFDG--------SFCPFVRSSYFPAPSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKTNPHPDLSD--------------------------------------VGKKSSEDEDED------------------------------------DACAPSHFCLSP--------------------------------------------------------RRV---------MSNSTDSSITFKHSD---------------------FSESED--------EITVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9PTU0-1", "uniprot_id": "DBX1B_DANRE", "id": "Q9PTU0-1", "name": "Homeobox protein DBX1-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMLPSVIAP-------------------------PAMYPSFLRPSSALSLPPALQS---------AFTTHSSFLVEDLLRISRP----------AAFMHRSIPSPSASPPATGVTTLNTTSSAVHVAMSTALAKRS-----------SSPQTSIS--SDPNYLKFGVNAILAST---------------TRNASPPPPVQGMNAKTFPFPCFDG--------SFHPFIRASYFPASSSAVPIPG--TFAWPLTARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLATKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKMNPNPDLSD--------------------------------------VGKRFEHEAVLR-----------------------------------ESPRAPFCQSRGD--------------------------------------------------------HEFN-------ADLHFKSPSISSKHSD---------------------FSESED-------EEITVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W064-1", "uniprot_id": "Q9W064_DROME", "id": "Q9W064-1", "name": "", "aln": "MSTAFLVDSLLHAQQTYTESQLKSSLSEMLLSRRSATGTDAADPADQPTESCGCSKLRGYKCDKCREIRAESVESIEEMDEDDGSSSADEIVADIGSVEGEEPHMDLDEELEEELADVDEPVSIKLPKVEPKETSMPTVGNTILKDTNSKPILKFSVSAILGDTREGVRVRNEFMQPQHIWPYLQQNFMQQHSHQYQQHHQQQQPHSHPQHQPLAVPGHQHSHPHSHHHHHHHPGAGHAHFPHPAFLTHQLPPHQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLPPGQGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQSASATPTPLPGTTVSSAAASPPGVTASEFQAKINAEMQKQLVAADLKFKLENSIQEAKQRRFEQLQQQLHHSPHFSAMREVELAAAAAAAQLHHHHQQQQQQQQQQHAQQQHAQQQHQGGSEFMKLYYDDYDDSNSDSDEEISVT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : * . : .: * . : : .. *.:**..:* .: . :. :.. *.* .. .* * . * . :*.. . ..*. : . . * : *: .. * .*:.. :...*:* *.*. ::********:******* ***.*** **:************* :****************************:***.*:****.* **:***** * : . . . :.. . : .: : :. : **:*:", "identical_positions": 107, "similar_positions": 83, "identity": "14.44%" }, { "cls_id": "homologset.agr.HGNC:33186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8VQH7-1", "uniprot_id": "F8VQH7_MOUSE", "id": "F8VQH7-1", "name": "Homeobox protein DBX2", "aln": "MDGPDTPSIPVLKTLSGSADRSRTLPEEPLRAKDSPLSPDPVRALSLSLRTRSPRLPGQRARTMLPSAVAAQAGAYWDVVASSALFGLP-APGFGSLGKSFLIENLLRAGAGPT-----HAPPPPRPAPGPECPQLRPLPASPVPLKLCPAG--------PFGVRWAFQMP---------PGRAPGERDSAFQPSAPVPSKPFLLSAPPFYSACCGGSCRRPASPTAFSREEHGLPLLTQDSNSKARRGILRRAVFSEEQRKALEKMFQKQKYISKTDRRKLAVSLGLKESQVKIWFQNRRMKWRNSKEKEVLSSRCLQEVSLQEDRLARPAVGCPPQCPSIWEVSQPHSSPSWREETPESAERLTQENSGVL--EADSLRGTLYLCPEKGPRDKHGLQSTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LRM4-1", "uniprot_id": "F1LRM4_RAT", "id": "F1LRM4-1", "name": "Homeobox protein DBX2", "aln": "MDGSDTPSIPVVKTQSGSADCSRTLPEALLRAKDALRSPDPAGALSRSPRTRSPRLPGQRARTMLPSAVAAQAGAYWDVVASSALLGLP-APGFGSLGKSFLIENLLRAGAGPT-----HAPPSPRPAAGPECPQLRSLPANPVPLKLCPAG--------PFGARWAFQMP---------PGRAPGERDSAFQPSAPVPSKPFLLSAGPFYSACCGGSCRRPASPTAFSREEHGLPLLTQDSNSKARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRRKLAISLGLKESQVKIWFQNRRMKWRNSKEKEVLSNRCLQEVSLQEDRLAQPAAGCPPQCPSVWEVSQPHSSPSWREESPESVERLSQENSGVP--EAGSLRGVLYLCPEKGPRDKDGLCSAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZNG2-1", "uniprot_id": "DBX2_HUMAN", "id": "Q6ZNG2-1", "name": "Homeobox protein DBX2", "aln": "---------------------------------------------------------------MLPSAVAAHAGAYWDVVASSALLNLPAAPGFGNLGKSFLIENLLRVGGAPTPRLQPPAPHDPATALATAGAQLRPLPASPVPLKLCPAAEQVSPAGAPYGTRWAFQVLSPSADSARLPGRAPGDRDCTFQPSAPAPSKPFLLSTPPFYSACCGGSCRRPASSTAFPREESMLPLLTQDSNSKARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWFQNRRMKWRNSKEKEVLSNRCIQEVGLQEDPLSRSALGFPSPCPSIWDVPQQHSSPRWRENSPEPSERLIQESSGAPPPEANSLQGALYLCSEEEAGSKGVLTGAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********:*************:.** *****.************.*..** ** * .* .. .***.***.*********. *:*.*****: ******:**.:******.********: ****************.***.*** ************************:********************:***:.*****************************.**:***.**** *::.* * *. ***:*:*.* **** ***::**. *** **.**. **.**:*.****.*: . .* * .::", "identical_positions": 236, "similar_positions": 53, "identity": "58.71%" }, { "cls_id": "homologset.agr.HGNC:33187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVW0-1", "uniprot_id": "A0A8I5ZVW0_RAT", "id": "A0A8I5ZVW0-1", "name": "", "aln": "-MAGAAGGGGAGLAVSTGLEAATLQKLALRRKKVLGAEEMELYELSQAAGAAIDPDVFKILVDLLNLNVAPLAVFQMLKSMCAGQRLASDPQ-DSVSMSLSTSTS-ETRGRNRGGPILGNVTIVAERGSRERPIQRMPRQPSATR---LPKVGGPGKSNSRSSP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ25-1", "uniprot_id": "MZT2_MOUSE", "id": "Q9CQ25-1", "name": "Mitotic-spindle organizing protein 2", "aln": "MAAAAAAAGGAALAVSTGLETATLQKLALRRKKVLGAEEMELYELAQAAGAAIDPDVFKILVDLLNLNVAPLAVFQMLKSMCAGQRLASDPQ-DSVPISLSTSTS-ETRGRNRGGPILGNVTISAERGSRERPIQRMPRQPSATR---LPKVGGSGKSNSRSSP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P582-1", "uniprot_id": "MZT2A_HUMAN", "id": "Q6P582-1", "name": "Mitotic-spindle organizing protein 2A", "aln": "-MAAQGVGPGPGSAAPPGLEAAR-QKLALRRKKVLSTEEMELYELAQAAGGGIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQ-DPAAVSLPTSSVPETRGRDKGSAALGGVLALAERSNHEGSSQRMPRQPSATR---LPKGGGPGKSPTQGST-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DC17-1", "uniprot_id": "MZT2_DANRE", "id": "Q6DC17-1", "name": "Mitotic-spindle organizing protein 2", "aln": "-MPSAPDSPSLSVNVSG-----NVQKYSIKKKKVLNAEETELFELTQAAGVVIDQEVFKIIVDLLKMNVAPLAVFQTLKTMCAGQKVSETSTGDASSTSHTTAVPTESRVRSKMSSGQG------EKSARESSSQRVPRQVSATRGQKSTKSSGSSSSSSQLTSN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . .. ** ::::****.:** **:**:**** ** :****:****::********* **:*****:::. . *. . * .*: *:* *.: .. * *:. :* . **:*** **** .* .*...* :: :. ", "identical_positions": 63, "similar_positions": 48, "identity": "38.18%" }, { "cls_id": "homologset.agr.HGNC:33188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3J8-1", "uniprot_id": "AMTN_MOUSE", "id": "Q9D3J8-1", "name": "Amelotin", "aln": "MKTMILLLCLLGSAQSLPKQLNPASGVPATKPTPGQVTPLPQQQPNQVFPSISLIPLTQLLTLGSDLPLFNPAA-GPHGAHTLPFTLGPLNGQQQLQPQMLPIIVAQLGAQGALLSSEELPLASQIFTGLLIHPLFPGAIPPSGQAGTKPDVQNGVLPTRQAGAKAVNQGTTPGHVTTPGVTDDDDYEMSTPAGLRRATHTTEGTTIDPPNRTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3HS82-1", "uniprot_id": "AMTN_RAT", "id": "Q3HS82-1", "name": "Amelotin", "aln": "MKTVVLLLCLLGSAQSLPRQLSPALGAPATKPTPGQVTPLTQQQPNQVFPSISLIPLTQLLTLGSDLPLFNPAT-MPHGTQTLPFTLGPLNGQQQLQPQMLPIIVAQLGAQGALLSSEELPLASQIFTGLLIHPLFPGAIQPSGQTGAKPDVQNGALPTRQAGASPANQATTPGH-TTPAVTDDDDYEMSTPAGLQRATHTTEGTTMDPPNRTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UX39-1", "uniprot_id": "AMTN_HUMAN", "id": "Q6UX39-1", "name": "Amelotin", "aln": "MRSTILLFCLLGSTRSLP-QLKPALGLPPTKLAPDQGTLPNQQQSNQVFPSLSLIPLTQMLTLGPDLHLLNPAAGMTPGTQTHPLTLGGLNVQQQLHPHVLPIFVTQLGAQGTILSSEELP---QIFTSLIIHSLFPGGILPTSQAGANPDVQDGSLPAGGAGVNPATQGTPAGRLPTPSGT-DDDFAVTTPAGIQRSTHAIEEATTESANGIQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :**:*****::*** **.** * *.** :*.* * ***.******:*******:****.** *:***: . *::* *:*** ** ****:*::***:*:******::******* ****.*:**.****.* *:.*:*::****:* **: **.....*.*..*: .**. * ***: ::****::*:**: * :* :..* :", "identical_positions": 121, "similar_positions": 61, "identity": "56.54%" }, { "cls_id": "homologset.agr.HGNC:3319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWM8-1", "uniprot_id": "D3ZWM8_RAT", "id": "D3ZWM8-1", "name": "", "aln": "-MAIALQPSDLVFEFASNGMDD-IHQLEDPS--------------------------------VFPAVIVEQVPYPELVHLYSGLDLDEVHSGIIRDRTLCMTQDQILEGSILLTDDNVSTSN----NSSSTEVLFNVATPSDVLDEKQIFSTPEVLP----------DSNSVQAINLPNFLLSTPEPDDPKKTSDAGDQKEYS-LEEVSREENLRKIGKSRKRNRKTKNNRSTSPVTDPSVPIRKK-------SKDGKGSTIYLWEFLLALLQDRNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESTETPEDSSQASTSSTPS-----TSTTRRPSSRVVTRASPEDKDSPSWEKPKVEHTGLQPSASLELGLSVDEEVPTTSTMIVSPLQSQAKPAKTVSTS-APSNIHLGVAP--VGPGSTVTLQTIPLTTVLTNGPPAGTTAPAQLVLQSVPQVST-FKDTLTLQTSFPLNA-SLQENQVATQGTPLILSGLPQLLAGANHQSNPVTSQVIG-AGSAGP-SSQPPGTVIAAFIRT---------------SNGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQAHLQPLQSQALSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSSSGSLLVTEPNMTTSGSLLTRSPTQAPFSPFNPTS-----LIKMEPHDI----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2U4-1", "uniprot_id": "ELF4_MOUSE", "id": "Q9Z2U4-1", "name": "ETS-related transcription factor Elf-4", "aln": "-MAIALQPSDLVFEFASNGMDD-IHQLEDPS--------------------------------VFPAVIVEQVPYPELVHLCSGLDLDEVHNGIIRDRTLCMTQDQILEGSILLTDDDVSTSN----NVSSTEVLFNVATPSDVLDEKQIFSSPEVLS----------DSNSVQAINLPNFLLSTPEPDDLKKTSDAGDQKEHSEEEKVSREENLRKMGKARKRNRKTKNNRSTSPVTDPSMPIRKK-------SKDGKGSTIYLWEFLLALLQDRNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESPETPEDSSQASTSSTPS-----TSTIRRASSRVGTRASPEDKDNPPWEKPKVQHTGLQPSASLELGLSVDEEVPTTSTMLASPLQSQARLTKTVSSSPAPSNIHLGVAP--VGPGSTVTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPQVST-FKDTFTLQTSFPLNT-NLQENQVATQGAPLILSGLPQLLAGANPQSNPAPSQVIG-AGSAGP-SSQPPGTVIAAFIRT---------------SSGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQGHLQPLPSQVLSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSGSGPLFVTEP-------SVTRSPTQAPFSPFNPTS-----LIKMEPQDI----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99607-1", "uniprot_id": "ELF4_HUMAN", "id": "Q99607-1", "name": "ETS-related transcription factor Elf-4", "aln": "-MAITLQPSDLIFEFASNGMDDDIHQLEDPS--------------------------------VFPAVIVEQVPYPDLLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLTDDNEATSH----TMSTAEVLLNMESPSDILDEKQIFSTSEMLP----------DSDPAPAVTLPNYLFPASEPDALNRAGDTSDQEGHSLEEKASREESAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKK-------SKDGKGSTIYLWEFLLALLQDRNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDESSEATAAPPQASTASVAS-----ASTTRRTSSRVSSRSAPQGKGSSSWEKPKIQHVGLQPSASLELGPSLDEEIPTTSTMLVSPAEGQVKLTKAVSASSVPSNIHLGVAP--VGSGSALTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPAAST-FKDTFTLQASFPLNA-SFQDSQVAAPGAPLILSGLPQLLAGANRPTNPAPPTVTG-AGPAGP-SSQPPGTVIAAFIRT---------------SGTTAAPRVKEGPLRSSSYVQGMVTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSRPTVGLTPVAELELSSGSGSLLMAEPSVTTSGSLLTRSPTPAPFSPFNPTS-----LIKMEPHDI----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2K0-1", "uniprot_id": "A0A8M6Z2K0_DANRE", "id": "A0A8M6Z2K0-1", "name": "", "aln": "-MTTVVQANELVFEFASNGMDE-INQLDDPS--------------------------------VFPAVIVEQVPAADLMQVYSGLEADEVTNGIMVDAIQDVVEENMMGDVGLSVETPVSGGEDNMETIEAAEALLNMESPNNILDEKRMIHTYGNIL----------ETD-LSYISLR--------PEHLSNGMDVAHDDETSSLDEVP-QKNFSKPAR-KTKVRKPRPARPCSPITNPSLPLKKK-------SKEGKGNTIYLWEFLLALLQDKNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPTDLVIIDEDD--GQGDDGGAGYGGHRAAP-----HGRVGRGSSRSQGRNT----------QVKTVKREMSPGLNSRNGKQAEQLLQTVHVLQPNQGAAVPAQTHSVRTINMPGSVPMVLTSG-AQGGGPMTLQTLPLSSVLTNGDSSTHASPPRVILHTVPSTSPGGKDVLTIQTASLTTD-SLHSQQLLVSTLSSSSGGVISTTPQQTASLNGITRLVTLNANGQPV-VAQQPGTVIATVLKP---------------SEYQSLQVKEE--ISDPQYFQSLVNNSPSFASFCKDEIAEGMAEMS-----YRTVIINTAGQELSQSLNGHSQLASSPSEGLTPVEELEVRGEVALHPEPEAKELLESSQGLQELPVTMQIPASHFI-----QVKAEPTET----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11536-1", "uniprot_id": "E74EB_DROME", "id": "P11536-1", "name": "Ecdysone-induced protein 74EF isoform B", "aln": "MIMVQHLVAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPG--AIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKVLYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKSLMKRYYTEIPIVKQSTSPAPQQQLQQQHHLQQQQQQQPHNGSTFAGATALLHIKTEQNTLLTPLQLQQQQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQNNAANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEIDCNGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:***:. . :: ...* * *: .. . :* : :: . : : ::::: .. . :* :: :*. : . * ::: : . . :. * :... * :. .. . :* :..: . :.. .: * ** *: .* :. . . . :.***: *: . .: : .: . * : *: .. :*. .:: ::.:. . :: : : : : . . * . : : : * :. .. . : : :.* .. .:: : ... .*. . : :: .: :: . .: . . : .* ** : :: :.. . : :: . . * . : . : . . : : * * * . : . . .. . . : . :: . . ", "identical_positions": 36, "similar_positions": 179, "identity": "4.07%" }, { "cls_id": "homologset.agr.HGNC:33193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPI2-1", "uniprot_id": "D3ZPI2_RAT", "id": "D3ZPI2-1", "name": "", "aln": "MKLLLWACIMCVAFAKRRRYPFIHKKSPSSTEEDYFGNRYPLKPSLNIPYGLWNDNLPPFVLPPLNTQQGNAITKFSGNSELERGLSLYPWIPTSPKFRYIYQNYNYPADAPLNGPAIVPLPPPRPFPPRPYPFVIPPKISVISPIGHEPVAASAVPAEGEALVPEIPVDKHIAGLPPVIKLATPMPPSEPKSLAPEPAPAHFAAPEPVPVHFLAPEPAHPQPEMAVPAAPHPMAPEPAVALSVGAQPLEAETPAGQSPENKPTSGELAVAQSLPTLPAAGQPPPDELMASQSLVGKLITAEPTEAKQEGPEPFEAKSASHEPQVFYQMLMNQSET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6MZM9-1", "uniprot_id": "PRR27_HUMAN", "id": "Q6MZM9-1", "name": "Proline-rich protein 27", "aln": "MKLLLWACIVCVAFARKRRFPFIG--------EDDNDDGHPLHPSLNIPYGIR--NLP----PPLYYRPVNTVPSYPGNTYTDTGLPSYPWILTSPGFPYVYHIRGFPLATQLN------VP---PLPPRGFPFVPPSRF----------FSAAAAPAA-----------------PP---------------IAAEPA-----AAAPLTATPVAAEPAAGAPVAAEPAAEAPVGAEPAAEAPVAAEP-AAEAPVG-------------------VEPAAEEPSP---------------AEPATAKPAAPEPHPSPSLEQANQ------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:*****::**:*** ** .: :**:********: *** *** : *::..:.**: : **. **** *** * *:*: .:* : ** :* *:*** :*** *.:: .:*:*.** ** :*.*** *. *:.. :*.*** * * *** *:..***. .*.*:* **:*.* . *** :*.* ***: ** .***. : * .: * ", "identical_positions": 111, "similar_positions": 60, "identity": "33.04%" }, { "cls_id": "homologset.agr.HGNC:33194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97830-1", "uniprot_id": "UNC4_RAT", "id": "P97830-1", "name": "Homeobox protein unc-4 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MMDGRLLEHPHAQFGGSLGGVVG--FPYPLGHHHVYELAGHQLQSAAAAAAAASVPFSIDGLLSGSCAAAAASVVNPTPLLPAACGVAGESQPFKLADSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALAVRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQSRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPTASAKGPGAHGSGIAGSAPVPPGEPPAPGTCDPAFYPSQRSGAGSQPRLGRPADKDTVPCGPGAAST------AGLPKASPFSVESLLSDSPPRRKATP-ANTAATAGLDFTPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGPELVPKDAPPAPPAPPAPPAQASFGAFPGPVGAADPAFARRSPEVVASPGP--PAPASFRGLA-AAAAESGAGDCADAGTVCPAAPPPPPLETSPGPGPRAPSPPGEPATCGAAEPG----AATGSSPPEGEEVDMD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08934-1", "uniprot_id": "UNC4_MOUSE", "id": "O08934-1", "name": "Homeobox protein unc-4 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MMDGRLLEHPHAQFGGSLGGVVG--FPYPLGHHHVYELAGHQLQSAAAAAAAASVPFSIDGLLSGSCAAAAASVVNPTPLLPAACGVAGESQPFKLADSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQSRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPTAAAKGPGAHGSGIAGSAPVPPGEPPAPGTCDPAFYPSQRSGAGSQPRLGRPADKDTVPCGPGAAAT------AGLPKASPFSVESLLSDSPPRRKATP-ANAAATAGLDFTPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGPELVPKDAPPAPPAPPAPPAQASFGTFPGPGGAADPAFARRSPEVVASPGP--PAPASFRDLT-AAAAESGAGDCADVGTVCPAASPPPPLETSPGPGPRAPSPPGEPATCGAAEPG----AATGPSPPEGEEVDMD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJT0-1", "uniprot_id": "UNC4_HUMAN", "id": "A6NJT0-1", "name": "Homeobox protein unc-4 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MMDGRLLEHPHAQFGGSLGGVVG--FPYPLGHHHVYELAGHQLQS---AAAAASVPFSIDGLLGGSCAAAAS-VVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPP--AAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAP---SPRPGPRPPSPAEEPATCGVPEPG----AAAGPSPPEGEELDMD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q50D79-1", "uniprot_id": "UNC4_DANRE", "id": "Q50D79-1", "name": "Homeobox protein unc-4 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MMDSRILEHPHAQFGGSLGSMVGMGFPYHLGHHHVYDISGHQLQS------AAAVPFSIDGLLNGSCS---GSVANSNPLLGSGCGVNGDSQ-YKLGDGGDPDKESPGCKRRRTRTNFTGWQLEELEKASNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARRELERLEKKKRKQERKLLKSQNKLLAG----ELFHTPGSDSDSGVSQSTDSES-------------TPHTGPQHSAHRQQTEHICEQHAR-----HQRASTVNETAEPMDSTRNSGLCPANGITR-----ASTLQKLNPFSVESLLADSSPRR----------KTILDFSQ--LPPQRPLVGKGHFLLYPITQPLGFIVPQTAMKQ-------SHDSGNS--GHHCSTTDTSTSNQ-----KNVNHLCRDNTGASDELQR--ETKNSSIQSPSTSSEKCFS----ESNSPQKESENDSESTVTN--SSQKESISANLSEYSDRKSR-----SSADTNTDGEDVDMD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IVX3-1", "uniprot_id": "A0A0R4IVX3_DANRE", "id": "A0A0R4IVX3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MMDSRILDPPHAQFGGSLGGMV--SFPYHLSHHHVYELAGHQLQS------TAAVPFSIDGLLNGSCT---ASVVNSNPLLSSGCGMNGDNQQYKLTDSGDPDKDSPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLIESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARRELERLEKKKRKQERRLLKSQNKLLPG----DLFHTPGSDSDSGLSQITDSEQ-------------SLHCDMGR-NQTQPSCDQTPQKLQ-----NQRNADQDASGSELDSSDSGQQSNLCSNSR-----SSALQKLNPFSVESLLSDSRPRR----------KPPMDFP---VPTPRPLIGKGHFLLYPITQPLGFIVPQTALKS-------TAPGPDTENGQKGPATDITFAGNPGHRNAKENNSVNNNSGARAIKGQ--VSQSGNISCSTQSSSPQTTINGHSAGSCNERCPQDIELELVDPKSPQSEKKEQSLPDYPPQNSESA--TTSKDTDKDSVDVDME--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O77215-1", "uniprot_id": "UNC4_DROME", "id": "O77215-1", "name": "Homeobox protein unc-4", "aln": "MVLETSEGDTKKFLTNNNNSSASRNNNSHNNNNNNHSPKEIPEETGRSSSTSSNSIPNAHRTNAGQHLLGGSPSSACSTSVSGCGMPSEGLHPTAALQLYAAAAQLAPNGVRVPPWGPFLQFGVPGVFGPNGPFLGRPRFDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTVATIQHRLMIGNRQSLPPAG-PPSEGSNEDGGFPGDGDDDSSAAKRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTKKGPGRPAHNAQPQTCSGEPIPPNELKAKERARR----RKKLAKAIDRQARKLQA------------------------------------------KGITVDLEALKAEYISQ---------HKANGTFSDSDLEDDG---IQIDVVGGTDS------DDEGDSDAVSPVRLGGGGGGGG----------------------------GTGGGGGGGASSSLHCGLDGDGDSSRAGSFIGGGGSLGSPSSVAPPSMLSNGAVQFGKLEPMDGNESEERDRERDSPKPLLFPAKAFHQLNLQSSQQHHGLVVGQGQGSGSGHGHGHQHNHHQHHLHHGSASASAAAAVANLVHQTSPISMRRSNPFSIESLLFNNT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VX20-1", "uniprot_id": "Q9VX20_DROME", "id": "Q9VX20-1", "name": "Homeobox protein unc-4", "aln": "---------MDQLIQQLQQAAAARGQVQHP-------------------------------------------------------------HGSSALQLYAAAAAVN---MQVSGWSSVLNLSMD---APNPEISPNSVTNSSSVYMIRQMALIQQARVAAAAVAMQQQQQQQRDLNRELGMDPHSEQRIKLDSVSPT-----HNIHAGSSRGIKQDP-LSDEGADSNLGQ----NDCTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAHPQSCSGDPIPLSELRARELAQR----SKRMKKAIDRQAKKLQD------------------------------------------KGLEVDYARLEAEYLAA---------HQENGVDENNWLDDDGYDDLHIDVVG------------------VEPEYVTG---------------------------------------------DSLDH-------------------SFCSSRTYQTKSTSS----------ELDSNDMGLQGRVETPPPP---------QPPMQNKTLYN-------------------------------------------------------SPFSIESLLGS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . *. : : .: . : .:. . :. : ..*:** ****..***.***:. . *****:******* :*** *.*: ********* **:*:***********::* :***:*: .*: :* : *: : :. * : * . : . . .. : . ..* . : . . . .: . ", "identical_positions": 65, "similar_positions": 67, "identity": "9.54%" }, { "cls_id": "homologset.agr.HGNC:33196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7Z9-1", "uniprot_id": "PLIN5_RAT", "id": "M0R7Z9-1", "name": "Perilipin-5", "aln": "--MDQRGKDTTLALHSRMSGDQTAQDPGSSLGELDQHNVVKRVVALPLVRATCTAVSGAYNSAKDRHPLLGSACRFAEHCVCSVATCALDHAQPLLEHLQPKLATVNDLACRGLDKLEEKLPFLQQPSDTVVTSAKDAVAKSVTGVVDLAQRGRRWSGELRRSVSQ-----AMDTVLRRSVSQAMDTVLGKSEELVDHFLPMTEAELVALATESQGPEVGSVEEQRQKQGYFVRLGSLSARLRHLAYQHSLGKLRESKHRTQEMLAQLQKTLELIQHMQSRASPTPTFHHPKVQELCGDWSPCLENG------------------YRHSQVELETLALSRSLTLELQSAVDALAGCVRGLPPSAQAKVAEVQRSVDALQATFADAHCLGDVAPTALAEGQDSVAQAHACVDEFLDLVLRAMPLAWLVGPFAPILVERSEPLINLATCVDEVVGDPDPRWAHMDWPAQQRAWEAEPADPGG---------------QEAEPPLGQVKHTMMPELDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVZ1-1", "uniprot_id": "PLIN5_MOUSE", "id": "Q8BVZ1-1", "name": "Perilipin-5", "aln": "--MDQRGEDTTLAPHSRMSGDQTAQDPGSSLGELDQQNVVNRVVALPLVKATCTAVSSAYNSAKDRHPLLGSACRLAEHCVCSVTTCALDHAQPLLEHLQPQLATVNDLACRGLDKLEEKLPFLQQPSDMVVTSAKDTVAKSVTGMVDLAQRGRRWSGELR-----------------RSMSQAMDMVLGKSEKLVDRFLPMTEAELAVLAAEAEGPEVGTVEEQRQQQGYFVRLGSLSARLRHLAYEHSLGKLRQSKHRTQEMLAQLQETLELIQHMQRGASPSPTFHPPKTQELWGSWSPCLENG------------------RSHSEVELETLALSRSLTLELQNAVDALAGCVRGLPPSAQAKVAEVQRSVDALQATFADAHCLGDVAPTALAEGRGSVARAHACVDEFLDLVLRAMPLPWLVGPFAPILVEQSEPLINLATCVDEVVGDPDPRWAHMDWPAQKRAWEAESADPGG---------------QEAEPPRGQGKHTMMPELDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00G26-1", "uniprot_id": "PLIN5_HUMAN", "id": "Q00G26-1", "name": "Perilipin-5", "aln": "-----------------MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELK-----------------RSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPES------------------RRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGJ3-1", "uniprot_id": "F1QGJ3_DANRE", "id": "F1QGJ3-1", "name": "Perilipin", "aln": "------------------MADNVKTAEKDKEDSQEQQSVISRVGNLPLVSSACGAVYNAYSSTKDSVPLLKGVMEVAESGVRTLGAAASTGSKPILDRLEPQIAAVNEYAIKGLEKVEGNLPILQQPADKLVSDTVGMVYQSVTGAKDAVVGAVMEGVEKTRMAVTGGINTVMGSRVGQMVSNGVDKALTHSEDWVEQNLPISEKELATLAEPRPGEEEGFIVSTR--SSYFVRLGKLSAKVRERALEQSLLRARKARDTTHASVTQMTSTMDLLESARVTLTSANQQLAGAPEQLLQRWKEWKEGQPKELQEKVTAETEADGAKDKEQEMESKALLMVRGLSDQLKTACSGVVSSVQGLPGTVQEQLLNARRTAGELQASLSGTKTL---TPVLLLQTRQQIGQVRQSLDGVVEYLLNNTPLNWLVGPFAPQITEKGE----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXY7-1", "uniprot_id": "LSD2_DROME", "id": "Q9VXY7-1", "name": "Lipid storage droplets surface-binding protein 2", "aln": "MASAEQKHATGNGTTGNGTAMNDVDQPKDAKDLLPHLESLERIIKLPVVNAAWDKSQDVYGKVKGKNRVFEWALTAAEDCVT----RAVTTAAPFVTKLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAKSKVIDVVQPHLERVVKFKAAG--------------------QQKAASLKDLAWQKAN-------EVLATQYGSLAVN--GVDTTTALAERLLEYYFPKCESDVE----EDNDDKQNAVVQNGKSSENDMPVPASEDPVLHTVQTVGRLSNKISRRVYRNVSRQIKQVQKGN---------------------INDYLSSLIAALKLHQYINFINSSMGTNVEQSGGSSSDACSPFGTTTSTTTTTTTSSTSNNKPVVALPHVAKSKRAPAVSSQ---------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :.*: **:* :: ..*. .*. :: . ** * * : *:: :*: :* ::. :*::*:* : *::::..: : ..: . * . * : . . : : * . ::: : : ** * : * . ** : . :.. : . :. :. . ::. : : .:: : .:* * :: ..: *. . :.. :: :.: . : . . . ", "identical_positions": 29, "similar_positions": 101, "identity": "5.63%" }, { "cls_id": "homologset.agr.HGNC:3320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A588-1", "uniprot_id": "A0A8I6A588_RAT", "id": "A0A8I6A588-1", "name": "ETS-related transcription factor Elf-5", "aln": "----------MLDSVTHSTFLPNASFCDPLMSWTDLFNNEEYYPAFEHQTAACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDANCISFCHFNISGLQLCSMTQEEFIEAAGICGEYLYFILQNIRSQGYSFFNDAEETKTAIKDYADSSCLKTSGIKSQDCH--TRTNLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDK3-1", "uniprot_id": "ELF5_MOUSE", "id": "Q8VDK3-1", "name": "ETS-related transcription factor Elf-5", "aln": "----------MLDSVTHSTFLPNASFCDPLMPWTDLFSNEDYYPAFEHQT-ACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDANCISFCHFNISGLQLCSMTQEEFIEAAGICGEYLYFILQNIRSQGYSFFNDAEETKTGIKDYADSSCLKTSGIKSQDCH--SRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKW6-1", "uniprot_id": "ELF5_HUMAN", "id": "Q9UKW6-1", "name": "ETS-related transcription factor Elf-5", "aln": "MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQT-ACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEDKL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********************.*****.**:********* *********************************:******:****************:****:*************:***********:*: *******.************* :**.*********************************************************************************************:**", "identical_positions": 238, "similar_positions": 14, "identity": "89.47%" }, { "cls_id": "homologset.agr.HGNC:33205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FS7-1", "uniprot_id": "TM183_RAT", "id": "Q68FS7-1", "name": "Transmembrane protein 183", "aln": "MARGPGQLSGPRPDTVTMPKRGKRLKFRAHDACSGRVTVADYANSDPAVVRSGRVKKAVANAVQQEVKSLCGLEASQVPAEEALSGVGEPSDILDSSDEMDAQEESTQERSVSRKKKSKRHKEDLDGAGGEEYPMDIWLLLASYIRPEDIVNFSLICKNAWTVTCTAAFWTRLYRRHYT-----LDASLPLRLRPESME--KLRCLRACVIRSLYHMYEPFAARISKNPAIPESTPSTLK-----NSKCLLFWCRKIVGNRQEPMWEFNFKFKKQSPRLKSKCMERLQPPIQYQDVHTNPDQDCCLLQVTTLNFIFIP--IVMGMIFTLFTINVS-----TDMRHHRVRLVFQDSPVRGGQHLRSEQGVQVVLDPVHSVRLFDWWHPQYPFSLRA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJB9-1", "uniprot_id": "TM183_MOUSE", "id": "Q9JJB9-1", "name": "Transmembrane protein 183", "aln": "MARGSGQLGGPHRDTVTMPKRGKRLKFRAHDACSGRVTVADYANSDPAVVRSGRVKKAVANAIQQEVKSLCGLEASQVPAEEALSGVGEPCDILDSSDEMDAQEESTQERSVSRKKKSKRHKEDPDGTG-EEYPMDIWLLLASYIRPEDIVNFSLICKNAWTVTCTAAFWTRLYRRHYT-----LDASLPLRLRPESME--KLRCLRACVIRSLYHMYEPFAARISKNPAIPESTPSTLK-----NSKCLLFWCRKIVGNRQEPMWEFNFKFKKQSPRLKSKCMERLQPPIQYQDVHTNPDQDCCLLQVTTLNFIFIP--IVMGMIFTLFTINVS-----TDMRHHRVRLVFQDSPVRGGQNLRSEQGVQVVLDPVHSVRLFDWWHPQYPFSLRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1AE95-1", "uniprot_id": "T183B_HUMAN", "id": "Q1AE95-1", "name": "Putative transmembrane protein 183BP", "aln": "MARGPGPLGRPRPDTVAMPKRGKRLKFRAHDACSGRVTVADYADSDLAVVRSGRVKKAVANAVRQEVKSLCGLEASQVPAEEALSGAGEPYDIIDSSDEMDAQEENIHERTVSRKKKSKRHKEELDGAGGEEYPMDIWLLLASYIRPEDIVNFSLICKNAWTVTCTAAFWTRLYRRHYT-----LDASLPLRLRPESME--KLHCLRACVIRSLYHMYEPFAARISKNPAIPESTPSTLK-----NSKCLLFWCRKIVGNRQEPMWEFNFKFKKQSPRLKSKCTGGLQPPVQYEDVHTNPDQDCCLLQVTTLNFIFIP--IVMGMIFTLFTINVS-----TDMRHHRVRLVFQDSPVHGGRKLRSEQGVQVILDPVHSVRLFDWWHPQYPFSLRA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9A5-1", "uniprot_id": "A1Z9A5_DROME", "id": "A1Z9A5-1", "name": "", "aln": "--------------------------------MSFDADCDEFIKN--KLFRS---------------KGKCDIYARQSDVCVAVK-----------------------QKSTFRATAPTLPMAEGNNNNVISMRYDIWFHISMHIDPEDVQTFALICKQTSRLVASRAFWRNLYRRHCTGATSGWNLNLPAELQLESIRNCKTRALKSLVIAALFHCHRPLKVRLELGYNLDWMLQRIFVSCFQTHYQCLWIMCYKFWNRQSHEQDETETHTGEVVNDWESLADD---DATKLAPTFCNPHEGVVLLVVICRHFVPTSNHLAYGPQQQRYRLRATRELLCTDMRAKNLELDFAEDGCRN-------VSVTVKHDRIEKYKVLPWWHPDFQRFVK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: .. :.** *. *.: * * . *:. :::. * . .. : :. . . ***: :: :* ***: .*:****:: :..: *** .***** * : .** .*: **:. * :.*:: ** :*:* :.*: .*:. . : : : :** : * *: ..:.. * : : : :* . . : .. **.:. ** * :*: . :. * : :..: **** :.:.* * :. :. .* * * :.. ::: ****:: :: ", "identical_positions": 69, "similar_positions": 110, "identity": "17.47%" }, { "cls_id": "homologset.agr.HGNC:33206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYE0-1", "uniprot_id": "A0ABK0LYE0_RAT", "id": "A0ABK0LYE0-1", "name": "", "aln": "------------------------------------------------------------------------------------------MPEDLALESNPSDHPRASTIFLSKSQTD---VREKRKSNHLNHVS---------------PGQLT-------KKYSSCSTIFLDDSTVSQPNLRTTIKCVTLAIYYHIKNRDANRSLDIFDERSHPLTREKVPEEYFKHDPEHKFIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPTNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLNFLFAPLSKERAQNLEAISRLCEDKY-KDLCRAAMRRSLSADNFI-----GIQRSNAILS----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YUJ3-1", "uniprot_id": "CCYL1_MOUSE", "id": "D3YUJ3-1", "name": "Cyclin-Y-like protein 1", "aln": "METRIRAAQLKGRGG------AFPKLGRRAGPAEPDYESEVYEAAAGDAVAVAPAPAAAVEPAELDFGAGEG--------HHLQHISDREMPEDLALESNPSDHPRASTIFLSKSQTD---VREKRKSNHLNHVS---------------PGQLT-------KKYSSCSTIFLDDSTVSQPNLRTTIKCVTLAIYYHIKNRDANRSLDIFDERSHPLTREKVPEEYFKHDPEHKFIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPTNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLNFLFAPLSKERAQNLEAISRLCEDKY-KDLCRAAMRRSLSADNFI-----GIQRSNAILS----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08CI4-1", "uniprot_id": "CCYL1_DANRE", "id": "Q08CI4-1", "name": "Cyclin-Y-like protein 1", "aln": "MGNTVSCCVSPSGS---------PKLPRQVERLE-DYQNNT------------------------DISDDTG--------PYLQHISDREVPDDLALESNPSDHARASTIFLSKSQTD---VRDRRKSNHINHVS---------------PGLLS-------KKYSSCSTIFIDDSTVSQPNLKSTIKCVTLAIYYHIKNRDSDRSLDIFDEKMHPLSREQVPDDYSRTDPEHKLIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAELDICPSNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLSFPLEPLSNERAQKLEAISRLCEDKY-KDLSRVAMRRSFSADNLV-----GIRRSNAVLS----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKF0-1", "uniprot_id": "Q9VKF0_DROME", "id": "Q9VKF0-1", "name": "", "aln": "MGNKNSCCAYSSPQSDRKSKDMPPVFEERIIQLGHPPHTSQHQLDGHHGSASAVHLHHHHHGHNQQQNQQGGGGDNYENQQNLQHISER---EALEGEEDPSVDPTAATMFLERSKVENGGMTRKRSQQQIAQQAGSGGGGGGGGGGGSTPGGNSCGGGGGMKKSSSCSTIYLDDSTVSQPNLKNTVKCVSLAIYYHIKNRQSDRRLDIFDEKLHPLTHDQVPDNYDTHNPEHRQIYKFVRTLFNAAQLTAECAIITLVYLERLLTYAELDVGPCNWKRMVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRTLAEANELNFPTEPLSKERAQKLEAMSRVMQDKVTAEALKNGIKKWSSMDNISQG---GPRRSVAILS----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C7X3-1", "uniprot_id": "CCYL3_HUMAN", "id": "P0C7X3-1", "name": "Putative cyclin-Y-like protein 3", "aln": "---------------------------------------------------------------------------------------------------------MACAVFQIP------------------------------------PWHLD-------RKYGSCSTILLDNSTASQPDLR------------HTLERYANRSLAIFEEPVHPLPQEKLPGKSFKHDPKRNCIFRHFCTLFQVIKLTAPCAIVALVYIKRLLTSANIDLCPTNWKKIVLGTMLLASKVWRNHGLWSVDDSQNSKDTAVENMSKMEKCFLELLEFNIHVSASVYAKYYFDLCALANDHDLYFLFSFLHKDKAQKLEGHT--SQHSLSLGPCRVGMENYATYSPLSSQPVLGALSLAEVLPQEIKQEIHQVLMDHGVPCHYTCFLLHPEDSTLERFLVLHSIQGLQEDSVLCKVEIHGLSPQPQTYQSHFRSPSLAELLNRISGTCRNHFAGMQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.::* * :* .***** :*:**.***:*: * :* ::* * **:* ***.::::* . :*::. *::.. ***.. :*** ***::***::**** *::*: * ***::***::******* ::.:*.** .* ** :**:*.::*: *****:***:*.:********** :**: ::* * * :::**:**. : :.. : .:.. : . : * :*. ", "identical_positions": 101, "similar_positions": 81, "identity": "19.96%" }, { "cls_id": "homologset.agr.HGNC:3321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4GTP4-1", "uniprot_id": "ELK1_RAT", "id": "A4GTP4-1", "name": "ETS domain-containing protein Elk-1", "aln": "---------MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSAVA-MAPATVHSGPGDNATGKPGTPKGAGMTGQGGLARSSRNEYMRSGLYSTFTIQSLQPQP--------------PLHPRPASVL-------------------------------------PNTTPAGVPAPPSGSRSTSPN---------------------------PLEACLEAEEAGLPLQVILTPPEAPNQKSEELSLNPGFGRPQPPEVKVE-GPKEELEVTEVGGFSPEAVKAEQEVSPS-----EGLLARLPAILTENTAQVCGLSTSTTEITQPQKGRKPRDLELPLSPSLLGGQGPERTPGSGTSSGLQAQG---PALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41969-1", "uniprot_id": "ELK1_MOUSE", "id": "P41969-1", "name": "ETS domain-containing protein Elk-1", "aln": "---------MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSAIA-MAPATVHAGPGDTATGKPGTPKGAGMTGQGGLARSSRNEYMRSGLYSTFTIQSLQPQPQ------------PPIPPRPASVL-------------------------------------PNTTPAGVPAPASGSRSTSPN---------------------------PLEACLEAEEAGLPLQVILTPPEAPNQKSEELSLDPSFGHPQPPEVKVE-GPKEELEAARAGGFSSEAVKAEPEVSAS-----EGLLARLPAILTENTAQVCGLSTSTTEITQPQKGRKPRDLELPLSPSLLGGQGPERTPGSGTSSGLQAPG---PALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19419-1", "uniprot_id": "ELK1_HUMAN", "id": "P19419-1", "name": "ETS domain-containing protein Elk-1", "aln": "---------MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIHAAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQP--------------PPHPRPAVVL-------------------------------------PSAAPAGAAAPPSGSRSTSPS---------------------------PLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGLGRALPPEVKVE-GPKEELEVAGERGFVPETTKAEPEVPPQ-----EGVPARLPAVVMDTAGQAGGHAASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPG---PALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UV82-1", "uniprot_id": "A0A8N7UV82_DANRE", "id": "A0A8N7UV82-1", "name": "", "aln": "MESNPLISAMDPSITLWQFLLHLLDDQNQKHLISWTSGDG-EFKLLDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVSGQKFVYKFVTYPDPNSADGLKGTEDSQRASTGEKLELSIQTKPMGGATTANQCLSKSLQVQRSSPSSVQRSSRNDYMKSGLYSTFTIQSLQTPCKGNSKLIKTEHVLNDCNPKPASLDRTMHEMRVCQTEGQQGSVQAQSTVESSNLQVIVTQPSPCATPALSPQTPSGSATAITNNQAQKSQSLGDPPQIYLSDPSSLTSLIPLPPGECVVNPSQHVFVVIKPPSVGQSKESSLSADEDLLEIVSLEDKADVEPVSAVPVPGVTDAPIPVDATSPCVEPVGPPVGEGEVKEKPELPEDTNTASASLQASTQDV-QPPKSKKPRVLELPSSSTLLP-PGLSLDKVNAAVNSLLASGSATNTLTPTVITSHSLTPVLLTPSPLPSTIHFWSTLSPIAPRSPAKLSFQFPSNGSNQIQIPALSVDGLSTPVVLSPGPQKP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:*******:** :*.: *:***** ** ****:************************************:************:**: ... . . :.: : *. :: : . . ... ... . :. ..: *****:**:*************. *:** : * ::** . ..*** :: .. ** . . :.. : *::.**.. : *...*. : .: . . * *.: * . : .. . . :. * . ** . * : :. . :*: :: ** *.:*** **** *.:** * . ..: ..* * * :***:::.:*:*********.**.:************************.** *::**::******************", "identical_positions": 200, "similar_positions": 117, "identity": "38.17%" }, { "cls_id": "homologset.agr.HGNC:33227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9M6-1", "uniprot_id": "D3Z9M6_RAT", "id": "D3Z9M6-1", "name": "", "aln": "MRVRLGALAGAAALSGALSFVLLAAAIGTDFWYIIDTERLEKSSPRMRDQ-GPVNRSQSEPLSSHSGLWRTCRVQSTCTPLMNPFWQENVTVSDSSKQLLTMHGTFVILLPLSLIVMVFGGMTGFLSFLLRAHLLLLLTGTLFLFGAMVTLTGISIYIAYSAVAFREAMCLLEERALLDQVDIRFGWSLALGWISFVSELLTGVVFLAAARVTNLSQRQEQAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D563-1", "uniprot_id": "TM114_MOUSE", "id": "Q9D563-1", "name": "Transmembrane protein 114", "aln": "MRVRLGALAGAAALSGALSFVLLAAAIGTDFWYIIDTERLERSSQRMRDQ-GPANRSQQEPLSSHSGLWRTCRVQSSCTPLMNPFWQENVTVSDSSRQLLTMHGTFVILLPLSLIVMVFGGMTGFLSFLLRAHLLLLLTGILFLFGAMVTLTGISIYIAYSAVAFREAVCLLEERALLDQVDIRFGWSLALGWISFVSELLTGVVFLAAARALSLSQRQDQAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B3SHH9-1", "uniprot_id": "TM114_HUMAN", "id": "B3SHH9-1", "name": "Transmembrane protein 114", "aln": "MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**.*******:**************************::. :* *. **** *****************.******** ******:**:******************:**************:*:******* **********:***:******.*****:*****:******** ************::*****..****** .* :**:***", "identical_positions": 183, "similar_positions": 26, "identity": "82.06%" }, { "cls_id": "homologset.agr.HGNC:33230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VGK1-1", "uniprot_id": "Q9VGK1_DROME", "id": "Q9VGK1-1", "name": "", "aln": "MKLPVICRTCDSTDTDNLLKLATPSKKYPDKLLSEILCELTEIN-LDATGSQKFPQCLCSGCTKKLMGAYCYVKQAMAANELLMKHLKNGAAP-TSTDCLQEAPMELCAEQHVEVKLETEDEDCGENDVTITCSELPEPDETDMESKKSVDPLTMIETVKLEMEPRSVEKPAYDDPTSDFEDEDSLDNLPLYNRIQKWKTGRKSVYKCHDCPRSFKRFDFLKRHEMRVHKPETRLYDCSLCIRKFSRSEALEAHLKIHRNSKRSANISEHKKAKAVDLNLCKP---HGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLCGRPNMEPHELAELFYPDSKDLSEEQLINLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDHDDQHKRRKKSRKATYSCELCQQKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECSECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKE-------HDIPLAETLIAATSRPNGAKR-ITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQPGVGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQCSSTEKKHACGKCSYKFMWPENLEQHILLQH-SKSSVSNPTGDRHTQGTGDLEKDATEDGIPLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMR--RHFDEVEAWLRRQK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8N4W9-1", "uniprot_id": "ZN808_HUMAN", "id": "Q8N4W9-1", "name": "Zinc finger protein 808", "aln": "MLREEAAQKRKGKESG--MALPQGRLTFRDVAIEFSLAEWKFLNPAQRALYREVMLENYRNLEAVDISSKHMMKEVLSTGQGNREVIHTGTLQRHQSYHIGDFCFQEIEKEIHNIEFQCQEDERNGHEAPTTKIKKLTG-STDQHDHRHAGNKPIKDQLGSSFYSHLPELHIFQIKGEIANQLEKSTSDASSVSTSQRISCRPQIHISNNYGNNPLNSSLLPQKQEVHMREKS--FPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHT--GEKPYKCEECDKVFSQKSTLERHKR--IHTGEKPYKCKVCDTAFTCNSQLARHRRIH-TGEKTYKCNECRKTFSRRSSLLCHRRLHSGE--KPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGEK--------------PYRCQVCDTAFTWNSQLARHTRIHT--GEKTYKCNECGKTFSYKSSLVWHR--RLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHR---------RLHSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIHGIGKFD----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:. ...::. : *. .: * :. *.* . :* : : ::. . :.: :*:.:::.: : ::.*: .: : : :: :: ::::: :::: . ::.. * : .** ..:: .. .: : : .: .: * :: . :: :. . . .: : * .:: .:: .. . .:* ::: : :: : *. . : *. *. *. * * ..*: * : : *: * * :* * ..:. :.* * . *..: . . : .. . : .. : *: : . . * . .:: . ... :. : . :: * :* : **.*: * : * :: .* *: .: *: * .** * . . *.:*:. :..:* : *: * * : :* * * * ::*::*.**::.*.::.** * .* * *: *...* :: ** * : * *:: :.: : ::::*. :* : **: .*. *. *:: .* * :*. . :: *. .. . : ** .:: :. * *::*.. . : :: :* * .: .::*::* . ** : ** : . **.: * *. *: . : :* :: *. .* .. .:: :. : : ..* :*..*.:*:. *: * * : :.. * : *. ** * ::** * * *****.:** :*: ** *:* ** * *:**.***::*. *** * ...:*.** *:* **:** *:* : : ..** * **** *: *. **: * : *** :*: :: :** ", "identical_positions": 177, "similar_positions": 330, "identity": "18.59%" }, { "cls_id": "homologset.agr.HGNC:33234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8N6-1", "uniprot_id": "LIN37_MOUSE", "id": "Q9D8N6-1", "name": "Protein lin-37 homolog", "aln": "MFPVKVKVEKSEMEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTPLDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPTVRERERSPGSPLPPLPEDGEGSEVINSKNRDVYKLPPPTAPGPLGDACRSRIPSPLQPETEGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A503-1", "uniprot_id": "D4A503_RAT", "id": "D4A503-1", "name": "", "aln": "MFPVKVKVEKSEMEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTLSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPTVRERERSPGSPLPPLPEDGEGSEVINSKNRDVYKLPPPTAPAALGDACRSRIPSPLQPETQGTTDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GY3-1", "uniprot_id": "LIN37_HUMAN", "id": "Q96GY3-1", "name": "Protein lin-37 homolog", "aln": "MFPVKVKVEKSELEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTPSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERECSPSSPLPPLPEDEEGSEVTNSKSRDVYKLPPPTPPGPPGDACRSRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYERQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************:********************************** ******************************************************************************:***** **.********* ***** ***.**********.*.. *************** :**.***************************************************:**", "identical_positions": 229, "similar_positions": 10, "identity": "93.09%" }, { "cls_id": "homologset.agr.HGNC:33237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCV3-1", "uniprot_id": "A0ABK0LCV3_RAT", "id": "A0ABK0LCV3-1", "name": "Dual specificity phosphatase 28", "aln": "----------------------------MGTSEA--------AQPPFARVAPALFIGNARAAGATELLVRAGITLCVNVSRQQ---PGPRAPGVAELRVPVFD------DPAEDLLTHLEPTCAAMEAAVRDGGSCLVYCKNGRSRSAAVCTAYLMRHRGHSLDCAFQMVKSARPVAEPNLGFWAQLQKYEQTLQAQA-------ILPQEP----TDPE------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTR5-1", "uniprot_id": "DUS28_MOUSE", "id": "Q8BTR5-1", "name": "Dual specificity phosphatase 28", "aln": "----------------------------MGTSEA--------APPPFARVAPALFIGNARAAGATELLVRAGITLCVNVSRQQ---PGPRAPGVAELRVPVFD------DPAEDLLTHLEPTCAAMEAAVRDGGSCLVYCKNGRSRSAAVCTAYLMRHRGHSLDRAFQMVKSARPVAEPNLGFWAQLQKYEQTLQAQA-------ILPREP----IDPE------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0W2-1", "uniprot_id": "DUS28_HUMAN", "id": "Q4G0W2-1", "name": "Dual specificity phosphatase 28", "aln": "----------------------------MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQ---PGPRAPGVAELRVPVFD------DPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQS-------CLQGEPPALGLGPEA-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE47-1", "uniprot_id": "F1QE47_DANRE", "id": "F1QE47-1", "name": "", "aln": "-------------------------------------------MLHLSAVTDCLLISNARSACNNDLIQKEAVTLCINVSKQQ---PFPSAR-VSTLRVPVYD------DPNEDLYRYFDRCADAIASEAGRGGRTVVYCKNGRSRSATVCVAYLMKHQSLTLTDAFQVVKSARSVVEPNPGFWSQLERYEQELKIRR-------SGSRKSK---LPPP------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAB0-1", "uniprot_id": "Q9VAB0_DROME", "id": "Q9VAB0-1", "name": "Protein-tyrosine-phosphatase", "aln": "---MQELIVGGIAISGVPFANETVEKESRQNQLSASTLEDHTPFPGLSRITPSLILCGA-AAVVPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQD------RSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRGSSSVAMVYFASLDKEIPDILEPEYRAMEDFYQRYRSSLKRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40479-1", "uniprot_id": "SDP1_YEAST", "id": "P40479-1", "name": "Dual-specificity protein phosphatase SDP1", "aln": "MNIYTSPTRTPNIAPKSGQRPSLPMLATDERSTDKESPNEDREFVPCSSLDVRRIYPKGPLLVLPEKIYLYSEPTVKELLPFDVVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKTN------VQANSYR---KVP-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : . . :: . ::: . : :: : : :::* * ****:: **:*:: . :* ::. ::: .*. *: ** .:* *. . * ", "identical_positions": 17, "similar_positions": 41, "identity": "7.17%" }, { "cls_id": "homologset.agr.HGNC:33238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71RI9-1", "uniprot_id": "KAT3_MOUSE", "id": "Q71RI9-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "MLLAQRRLISLGCRSKPIKTIYSSSKVLGLCTSAKMALKFKNAKRIEGLDSNVWVEFTKLAADP--SVVNLGQGFPDISPPSYVKEELSKAAFIDNMNQYTRGFGHPALVKALSCLYGKIYQRQIDPNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFYDCYEPMVRMAGAVPVFIPLRS-KPTDGMKWTSSDWTFDPRELESKFSSKTKAIILNTPHNPLGKVYTRQELQVIADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGP-AHLIKHLQTVQQNSFYTCATPLQAALAEAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLNSVGLKPIVPDGGYFIIADVSSLGADLSDMNSDEPY----DYKFVKWMTKHKKLTAIPVSAFCDSKSKPHFEKLVRFCFIKKDSTLDAAEEIFRAWNSQKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q58FK9-1", "uniprot_id": "KAT3_RAT", "id": "Q58FK9-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "MLLAQRRLFSLGCRAKPIKTIYSS-KVLGLSTSAKMALRFKNAKRIEGLDQNVWVEFTKLAADP--SVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRS-KRTDGMKWTSSDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKVASLPGMWDRTLTIGSAGKTFSVTGWKLGWSIGP-GHLIKHLRTVQQTSVYTCATPLQAALAEAFWIDIKRMDDPECYFNSLPKELEVKRDRMACLLNSVGLKPIIPDGGYFIIADVSSLGVDLSDVKSDEPY----DYKFVKWMTKNKKLSAIPVSAFCDSESKPHFEKLVRFCFIKKDSTLDAAEEIFRTWNSRKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6YP21-1", "uniprot_id": "KAT3_HUMAN", "id": "Q6YP21-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "MFLAQRSLCSLSGRAKFLKTISSS-KILGFSTSAKMSLKFTNAKRIEGLDSNVWIEFTKLAADP--SVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRS-KPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGP-NHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPY----DYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3E5-1", "uniprot_id": "KAT3_DANRE", "id": "Q7T3E5-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "-MHPIHLLRIVSSVRRLLQTNRCR--SFSSCQHNMASIKHKNARRIEGLDKNVWVAFTSVAADP--SIVNLGQGYPDIPPPSYVKEGLAQAAMVDRLNQYTRGFGHPTLVKALSKVYGKVYDRQLDPFKEILVTVGGYGSLFSTMQALVEEGDEVIIIEPFFDCYVPMVKMAGAKPVLIPLRL-KSTATTGISSADWVLDQEELASKFNSKTKAIIVNTPNNPIGKIFSRSELQAIADLCIKHDTLCFSDEVYEWLIYKGHEHVKIATLPGMWDRTITVGSAGKTFSVTGWKLGWSIGP-EHLIRHLQTVMQNSLYTCPTPLQEAVGRGLLRDFELMGQPDCYFSALALELEGKRDRMAAMLAQTGMTPVVPEGGYFMIVDVTALNQDLTHMGDDEPY----DYKFVKWMIKEKKLAAIPVTAFVGEDSVKQFEKYIRLCFIKQESTLDAAEAILKNWNKG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IBA4-1", "uniprot_id": "A0A0R4IBA4_DANRE", "id": "A0A0R4IBA4-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "----------------------------------MSSIKHKNAKRIEGLDKNVWVAFTSLAADP--TVVNLGRGYPDIPPPLYVKEGLAQAALVDQLNQSTRSFGHPTLVKALSKVYGKVCDRQLDPFKEILVTVGAYGSLFSTMQALVEEGDEVVIIEPFFDTYVPMVKMAGAKPVLIPLRL-KSTATTGISSADWVLDQEELASKFNSKTKAIIINTPNNPIGKVFSRSELQAIADLCIKHDTLCFSDEVYEWLIYKGHEHVKIATLPGMWDRTITIGSAGKTFSVTGWKLGWSIGP-EHLIKHLQTVMQNSLYTCPTPLQEAVGRGLLRDFELMGQPDCYFSSLALELEGKRNRMAAILAQTGMTPVVPEGGYFIMADVTALNQDLTHMGDDEPY----DYKFVKWMIKEKKLAAIPVSAFVGEDSVKQFEKYIRFCFIKQESTLDAAEAILKKWNKD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47039-1", "uniprot_id": "BNA3_YEAST", "id": "P47039-1", "name": "Probable kynurenine--oxoglutarate transaminase BNA3", "aln": "------------MKQRFIRQFTNLMSTSRPKVVANKYFTSNTAKDVWSLTNEAAAKAANNSKNQGRELINLGQGFFSYSPPQFAIKEAQKALDIPMVNQYSPTRGRPSLINSLIKLYSPIYNTELKAEN-VTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPINPPKELDQRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHLYFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYAAKAHTRICFASPSPLQEACANSINDALKIG-----YFEKMRQEYINKFKIFTSIFDELGLPYTAPEGTYFVLVDFSKVKIPEDYPYPEEILNKGKDFRISHWLINELGVVAIPPTEFYIKEHEKAAENLLRFAVCKDDAYLENAVERLKLLKDYL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..*: : .* .:. :. : : ::***:*: . . * :. : : : :** : *:*:*:::* :* : : ::.. : : *:.*. .::. : .*:: ****::: **:* * * :.:.*. * :*:. * . :*.:: .:: . :.*****:*:***:**:**::.*.** .:.::*:*::.: :****** * :.. : * : : *:*:*****:*:.***::** :. .*: : .. ::..:*** * ...: :: **. : * * . :. :: . *: *:* **::.*.: : :* *::: :*: :. : *** : * .. *: :*:.. *.:: *: * :: . ", "identical_positions": 97, "similar_positions": 164, "identity": "20.95%" }, { "cls_id": "homologset.agr.HGNC:33241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A514-1", "uniprot_id": "D4A514_RAT", "id": "D4A514-1", "name": "", "aln": "MEKVVTMETDLAEVPQKRALSSQDSLLSQEKS-AEGDVAALRLTARPQEAVTFKDVAMDFTPEEWGKLDPVHRDVMLENYRNLVSLWLPISKPDDYDSEDGKELLKLERKS---PKCSDSDVETRPESKESTSVLDFPKEES------DKRTQKTAFDPHVETALECEHWLEPQQGNREKHPRQVSTHPNSLPEEGDSECDVYWRNFSQKPCLMTDDRDLEGSCDFHTLEERLKQKSKFMKKQRPYKDKKPHKCDDCGELFTYHSVLIRHQRVHTGEKPYSCSECGKSFSHRANLTKHQRTHTRVLFECGECKKTFIESSALAVHQRIHIGERPYECGECGKGFNRSTHLAQHQLIHTGVKPYECNECDKAFIHSSALIKHQRTHTGEKPYKCQECGKAFSHCSSLTKHQRVHTGEKPYECSECGKTFSQSTHLVQHQRIHTGEKPYECHECGKTFSRSSNFAKHQRIHVGKKPYKCGECGKAFIHSSALIQHQRTHTGEKPFRCNECGKSFKCSSSLIRHQRTHTEEQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CG31-1", "uniprot_id": "Z286B_HUMAN", "id": "P0CG31-1", "name": "Putative zinc finger protein 286B", "aln": "------METDLAEMPEKGVLSSQDSPHFQEKSTEEGEVAALRLTARSQAAAAAAAPGSR-SLRGVHVPPPLHPAPAREEIKSTCSLKACFSLSLTLTYYRTAFLLSTENEGNLHFQCP-SDVETRPQSKDSTSVQDFSKAESCKVAIIDRLTRNSVYDSNLEAALECENWLEKQQGNQERHLREMFTHMNSLSEETDHEHDVYWKSFNQKSVLITEDRVPKGSYAFHTLEKSLKQKSNLMKKQRTYKEKKPHKCNDCGELFTCHSVHIQHQRVHTGEKPYTCNECGKSFSHRANLTKHQRTHTRILFECRECKKTFTESSSLATHQRIHVGERPYECNECGKGFNRSTHLVQHQLIHTGVRPYECNECDKAFIHSSALIKHQRTHTGEKPYKCQECGKAFSHCSSLTKHQRVHTGEKPYECSECGKTFSQSTHLVQHQRIHTGEKPYECSECGKTFSQSSNFAKHQRIHIGKKPYKCSECGKAFIHSSALIQHQRTHTGEKPFRCNECGKSFKCSSSLIRHQRVHTEEQP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:*:* .****** **** **:*********.* *.: . : . *:* *: :. ** :* . **. *.:. :*. *******:**:**** **.* ** *: *:::.:*.::*:*****:*** ****:*:* *:: ** ***.** * * ****:.*.**. *:*:** :** *****: *****::*****.**:******:******* *** *:***********:*.*********************:**** ****** ***:**.*****:*******.************.*********:**************************************************************************************** *******:***********:*******.*********************************************.*****.", "identical_positions": 379, "similar_positions": 69, "identity": "71.51%" }, { "cls_id": "homologset.agr.HGNC:3325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9V6-1", "uniprot_id": "D4A9V6_RAT", "id": "D4A9V6-1", "name": "", "aln": "-------------------MQGWLGMESAITLWQFLLHLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPDILKMDPHAVEISRES------LLLQDSDCKVSPEGREIHKHGLSSLKS-ASRNEYIHSGLYSSFTINSLQNAPEAFKAIKTEKLEEPCDDSPPVEEVRTVIRFVTNKTDKHITRPVVSLPSTSE-AAAAASAFLASSVSAKISSLMLPNAASVSSASPSSSRSPSLSPNSPLPSEHRSLFLEAACHDADSLEPLNLSSGSKTKSPSLPPKGKKPKGLEISAPQLLLSGTDIGSIALNSPALPSGSLTPAFFSAQTPSGLLLTPSPLLPSIHFWSSLSPVAPLSPARLQGPNTLFQFPTLLNGHMPMPLPSLDR---------APSPVLLSSSSQKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41971-1", "uniprot_id": "ELK3_MOUSE", "id": "P41971-1", "name": "ETS domain-containing protein Elk-3", "aln": "-------------------------MESAITLWQFLLHLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPDILKMDPHAVEISRES------LLLQDGDCKVSPEGREVHRHGLSSLKS-ASRNEYLHSGLYSSFTINSLQNAPEAFKAIKTEKLEEPCDDSPPVEEVRTVIRFVTNKTDKHITRPVVSLPSTSETAAAAASAFLASSVSAKISSLMLPNAASISSASPSSSRSPSLSPDSPLPSEHRSLFLEAACHDSDSLEPLNLSSGSKTKSPSLPPKGKKPKGLEISAPQLLLSGTDIGSIALNSPALPSGSLTPAFFTAQTPSGLFLASSPLLPSIHFWSSLSPVAPLSPARLQGPNTLFQFPTLLNGHMPVPLPSLDR---------APSPVLLSPSSQKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41970-1", "uniprot_id": "ELK3_HUMAN", "id": "P41970-1", "name": "ETS domain-containing protein Elk-3", "aln": "-------------------------MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRES------LLLQDSDCKASPEGREAHKHGLAALRS-TSRNEYIHSGLYSSFTINSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVRTVIRFVTNKTDKHVTRPVVSLPSTSE--AAAASAFLASSVSAKISSLMLPNAASISSASPFSSRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPLNLSSGSKTKSPSLPPKAKKPKGLEISAPPLVLSGTDIGSIALNSPALPSGSLTPAFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPIPSLDR---------AASPVLLSSNSQKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J6Y3-1", "uniprot_id": "A0AC58J6Y3_DANRE", "id": "A0AC58J6Y3-1", "name": "", "aln": "MFMWVSSVCSSFLHRPKTCAIGELDMESAITLWQFLLQLLLDQSHKHLICWTSNDGEFKLLKSEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPDILKMDPQAVELGRDGGHVAGGVMLQDVESDCG-EGEESPKLSLSSLRSPACRNEYLHSGLYSSFTVSSLQNPPPLLRPIKVENQRG-CERG---EEGQTVIRFVTNRSEKAIPLASSPPPSSGEVFFTSKSSPCSSRSPSPSHSPVYTLRHGQSPEARIDESEPSAQPLN-LSSSHR----ERAQNQASPLERR-------TSSNRLPPKARKPKGLEISAPSILLSGSDLGSIALNSPALPSGSLTPAFFTAQTPSGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGHSSLFQFPSLLNGPLPVPLPNLDSPSSSSSSSSSSSSLLLSSSGQKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ************:*****.*:****************:**************************************************:******:***:.*:. ::*** :.. . **.* : .*::*:* :.****:*********:.****.* ::.**.*: . : . ** :********:::* :. . . **:.* :: *: :* .: * : . . *. : .. .** .* . *.*.** * * :::..** *.* ****.:********** ::***:*:********************:****.**:*:.****.********************* .:*****:**** :*:*:*.** :.*.:***...***", "identical_positions": 246, "similar_positions": 96, "identity": "54.67%" }, { "cls_id": "homologset.agr.HGNC:33251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7K4-1", "uniprot_id": "G3V7K4_RAT", "id": "G3V7K4-1", "name": "Gap junction epsilon-1 protein", "aln": "MSLNYIKNFYEGCVKPPTVIGQFHTLFFGSVRMFFLGVLGFAVYGNEALHFSCDPDKREINLFCYNQFRPITPQV-FWALQLVIVLLPGAIFHLYAACKSINQECILQKPTYTVIYILSALLRISLEVSAFWLQIHLFGFQVKPVYLCDAESLGQKINTLKCMVPEHFEKTIFLIAMYTFTVITMVLCVAEIFEIIFRRSCFLFKR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX92-1", "uniprot_id": "CXE1_MOUSE", "id": "Q9CX92-1", "name": "Gap junction epsilon-1 protein", "aln": "MSLNYIKNFYEGCVKPPTVIGQFHTLFFGSVRMFFLGVLGFAVYGNEALHFSCDPDKREINLFCYNQFRPITPQV-FWALQLVIVLLPGAIFHLYAACKSINQDCILQKPVYTVIYVLSVLLRISLEVFAFWLQIHLFGFQVKPIYLCDTESLGKKPNILKCMVPEHFEKTIFLIAMYTFTVITMVLCVAEVFEIIFRRSCFLFKR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NN92-1", "uniprot_id": "CXE1_HUMAN", "id": "A6NN92-1", "name": "Gap junction epsilon-1 protein", "aln": "MSLNYIKNFYEGCVKPPTVIGQFHTLFFGSIRIFFLGVLGFAVYGNEALHFICDPDKREVNLFCYNQFRPITPQVSFSALQLVIVLVPGALFHLYAACKSINQECILQKPIYTIIYILSVLLRISLAAIAFWLQIYLFGFQVKSLYLCDARSLGEN-MIIRCMVPEHFEKTIFLIAINTFTTITILLFVAEIFEIIFRRLYFPFRQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "U3JA75-1", "uniprot_id": "CXE1_DANRE", "id": "U3JA75-1", "name": "Gap junction epsilon-1 protein", "aln": "MSLNYIKNFYEGCLRPPTVIGQFHTLFFGSVRTFFLGVLGFAVYGNEALHFSCDPDKRELNLYCYNQFRPITPQV-FWALQLVTVLVPGAVFHLYAACKNIDQEEILHRPMSTVFYIISVLLRIILEVLAFWLQSHLFGFLVDPIFMCDVTGLGKILNVSKCMVPEHFEKTIFLSAMYTFTIITILLCIAEIFEILFRRLGYLNQPMT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************::***************:* ****************** *******:**:************ * ***** **:***:********.*:*: **::* *::*::*.**** * . ***** :**** *..:::**. .**: :************* *: *** **::* :**:***:*** : : ", "identical_positions": 142, "similar_positions": 36, "identity": "68.27%" }, { "cls_id": "homologset.agr.HGNC:3326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41158-1", "uniprot_id": "ELK4_MOUSE", "id": "P41158-1", "name": "ETS domain-containing protein Elk-4", "aln": "MDSAITLWQFLLQLLQEPQNEHMICWTSNNGEFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILKMDPLT--VGRIEGDCEALNSIETSSS--KDVEYG---GKERPPQPGAKTSSRNDYIHSGLYSSFTLNSLNTSNKKLFKSIKIENPAEKLAEKKA-QEPTP---SVIKFVTTPAKKPPIEPVAAA-FATSPSLSPSSEETIQALETLVSPTLPSLETPASISILATTFNPTPPVPSTPLPLKEPPRTPSPPLSSNPDIDTDIESVASQPMELPENLS----LEPKNEDSALPEKDKTNNSSRSKKPKGLELTPALVVTGSDPSPLGILSPSLPTASLTPALFSQTPILLTPSPLLSSIHFWSTLSPFAPLSPARLQGANTLFQFPSVLNSHG-PFTLSGLDGPSTPGPFSPDLQKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28324-1", "uniprot_id": "ELK4_HUMAN", "id": "P28324-1", "name": "ETS domain-containing protein Elk-4", "aln": "MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMT--VGRIEGDCESLNFSEVSSSS-KDVENG---GKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTP---SVIKFVTTPSKKPPVEPVAAT-ISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIP-PLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLS----LEPKDQDSVLLEKDKVNNSSRSKKPKGLELAPTLVITSSDPSPLGILSPSLPTASLTPAFFSQTPIILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHG-PFTLSGLDGPSTPGPFSPDLQKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R0K1-1", "uniprot_id": "F1R0K1_DANRE", "id": "F1R0K1-1", "name": "", "aln": "MDSSVTLWQFLLQLLLDPGNEQLICWTNEDGEFKLLQAEEVARLWGARKNKPSMNYDKLSRALRYYYDKNIIKKVNGQKFVYRFVSYPDILKGDVMARAEGADGGSNGPLPLSDQPTNISRDKDNKSIIERGAGTLAQSKSSSRNEYIHSGLYTSFTLTSLQSG-TQLFKATKNENPGEKLMEKKSTQDSPQPLSTVIKFGTMPQKSTTASAIGRPELPEQSAQSPLADP--ESKQTSISNTVCAFVEKTSSENAMTGFPVSSISPSVLHHSSQSPSSSPMTDSQQLVIDSEIESLSSQPSELQLQVQPFSVSKATVSSCVLPESPPRNISSKSKKPKGLELMPTLVVTSSDLSPLNLSSPSLPTASLTPAFL-QTPLLLTPSPLLSNIHFWSTLSPVAPLSPARRQGAHNLFQFPSVLSSTQFTVPIYNLDGTNTPGPLSPDPQKT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::********** .* *:::****.::*:************** *****.************** **************:*****:**: * :: * *. .* : .:. :* : : . . :*:****:*******:****.**::. :*** * ***.*** ***: *:.. :**** * * *... ..:. . :. .: ** :: :: :* :* .: :: :* . * * :. .* .:.* :.. . *.: **::*:*::*** ** ::. :.. ....* *. * **:********* *:**:*.** ***.: ************:: ***::********.*********.******* ***:.********.* ...: .***..****:*** ***", "identical_positions": 224, "similar_positions": 117, "identity": "50.11%" }, { "cls_id": "homologset.agr.HGNC:33264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "J3QPR6-1", "uniprot_id": "J3QPR6_MOUSE", "id": "J3QPR6-1", "name": "", "aln": "MRKENLDSKHHYVKVSQDNLMENILEMEATCAICLDIYSHPIYLSCAHILCFDCGKKWMTKKEDLIMTCPVCRKEQKRPVKYDGVMKELAILLKQHGPLLKQHKGQITGLLRLVSENTALAAKTGDSSREPSNDLKGG---KPGHNLVEDPRRFISSAHVVDNSHFFS-VCHWEVDVEKRNEWAPGICKEPVSRRNIYLLREHKFQLLGEKTREIRVNFISERHHRSPGLYHVGIFLALTMEETKFVMGKATTLPMSIIISAFLELIPLF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWI9-1", "uniprot_id": "RFPLB_HUMAN", "id": "Q6ZWI9-1", "name": "Ret finger protein-like 4B", "aln": "--------------------MAKRLQAELSCPVCLDFFSCSISLSCTHVFCFDCIQRYILENHDFRAMCPLCRDVVKVPALEEWQVSVLTLMTKQHNSRLEQSL-HVREELRHFREDVTLDAATASSLLVFSNDLRSAQCKKIHHDLTKDPR----LACVLGTPCFSSGQHYWEVEVGEVKSWSLGVCKEPADRKSNDLFPEHGFWIS-MKAGAIHANTHLERIPASPRLRRVGIFLDADLEEIQFFDVDNNVLIYTHDGFFSLELLCPFFCLELLGEGESGNVLTICP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *: * :*.:***::* .* ***:*::**** :::: ::.*: **:**. * *. : :. *::: ***.. *:* :: ** . *:.:* * *..* ****:.. * *:*.:*** * *:... * * :***:* : :.*: *:****..*:. *: ** * : *: *:.* ** ** * :***** :** :*. . ..* : ***: * ", "identical_positions": 87, "similar_positions": 74, "identity": "30.1%" }, { "cls_id": "homologset.agr.HGNC:33267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCK4-1", "uniprot_id": "M0RCK4_RAT", "id": "M0RCK4-1", "name": "", "aln": "-MLKRKISPVGEGEAMSPPKKSYTLDMVSNKSPEASAEAKGEGAIVSQKTQAEMMEGDPKVCAQNCAPKQCKPMAGDAILPSPRDSLPEDSLHCKDGDSTVTGARVSNDCSAGTAGVPALSSSEARRYVSSLKP-TVTNYEIKCALMTEIRRFGRQYGRLFEILEEVQGPLEVRIQFVEFSIKEAARFKRRHLIQYLEKMLEKLKSERSLNSAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HYN5-1", "uniprot_id": "CT451_HUMAN", "id": "Q5HYN5-1", "name": "Cancer/testis antigen family 45 member A1", "aln": "MTDKTEKVAVDPETVFKRPRECDSPSYQ--KRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTG------FSKDRMMQKPGSNAPVGGNVTSSFSG--------DDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .*. .:. *::. : . * . : *: :** * : : * :.. : .: .*.* .. .* :.:* : * *..: .*..*:.. *. .. *.*. .** *. * :** *:.*:* .*::* ::**:** **** ** :*.* ****** **.::::*:* *::: ", "identical_positions": 54, "similar_positions": 69, "identity": "25.23%" }, { "cls_id": "homologset.agr.HGNC:33268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCK4-1", "uniprot_id": "M0RCK4_RAT", "id": "M0RCK4-1", "name": "", "aln": "MLKRKISPVGEGEAMSPPKKSYTLDMVSNKSPEASAEAKGEGAIVSQKTQAEMMEGDPKVCAQNCAPKQCKPMAGDAILPSPRDSLPEDSLHCKDGDSTVTGARVSNDCSAGTAGVPALSSSEARRYVSSLKP-TVTNYEIKCALMTEIRRFGRQYGRLFEILEEVQGPLEVRIQFVEFSIKEAARFKRRHLIQYLEKMLEKLKSERSLNSAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NHU0-1", "uniprot_id": "CT453_HUMAN", "id": "Q8NHU0-1", "name": "Cancer/testis antigen family 45 member A3", "aln": "-----MTDKTEKVAVDP----ETVFKRPRECDSPSYQKRQRMALLARKQGAGDS-----LIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSK-DRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *:.* *: ..:. ..* : : . *::::* * : * .. .*: * *:*.** ** ** :* .. * : . . ....:. : .. *.*. .** *. * :** *:.*:* .*::* ::**:** **** ** :*.* ****** **.::::*:* *::: ", "identical_positions": 57, "similar_positions": 65, "identity": "26.76%" }, { "cls_id": "homologset.agr.HGNC:3327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99372-1", "uniprot_id": "ELN_RAT", "id": "Q99372-1", "name": "Elastin", "aln": "MAGLTAAVPQPGVLLILLLN------LLHPAQPGGVPGAVPGGVPG----GLPGGVPGGVYYPGAGIGG--------------------------------------------GLGGGALGPGGKP---PKPGAGLLGAFGAGPGGLGGAGPG------AGLSYASR---PG-------------------------------------------------------------------GVLVPGGGAGAAAAYKAAAKAGAGLGG-------------------------------------------------------------------------------------------------------------IG---------GVPGGVGVGGVPGAVGVGGVPGAVGGIG--------------------GIGGLGVSTGAVVPQ-----------------LGAGVGAGGKPGK-----VPGVGLPGVYPGGVLPGTGARFPGVGVLPGVPTGTGVKAKVPGGGGGAFSGIPGVGPFG-GQQPGVPLGYPIKAPKLPGG------------YGLPYTNGKLPYG-------------------VAGAGGKAGY---PTGTGVGSQAA--------------------VAAAK--AAKYAGAGGGGVLPG-------VGGGGIPG-----------------------GAGAIPG------------------------IGGITGAGTPAAAAAAK------------AAAKAAKYGAAG-------GLVPGG------PGVRVPGAGIPGV-----------------------------------------GIPGVGGIPGVGGIPGVGGIPGVGG-PGIGGP---------------GIVGG---------------------------------------------------PGAVS-----------PAAAAKAAAKAAKYGARGGVG------IPTYG--VGAGGFPGYGVGAG--------AGLG-----------GASQAAAAAA-----------AAKAAKYGAG--------------------------------------GAGTLG---GLVPGAVPGALPGAVPGALPGAVPGALPGAV---------------PGVPG-----------TGGVPG----------------------------AGTPAAAAAAAAAKAAAKAGQY--------------GLGPGVGG---------VPGGVGVG---------------GLPGG-----------VGPG-GVTG-IGTG--PGTGLVPGDLGGAG-TPAAAKSAAKAAAKAQYRAAAGLG-----------------------AGVPGLG--------------------VGAG-----VPGFGAGAG---------------------------------GFGAGAGVPGFG--AG------------------------------------------------------------------------------------------AVPG-------------------------SLAASKAAKYGAAGGLGGPGGLGGP--------------GGLGG--------PGGFGGP---------------GGLGGVPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVAG--GAP--AAAAAAKAAAKAAQYGLG-----------------------------GAGGLGAGGLGAGGLGAGGLGAGGLGAGGLGAGG-----------------------VIPGAVGLGG-VSPAAAAKAAKYGAAGLGGVLG-ARPFPGGGVAARPGFGLSP---------IYPGGGAGGLGVGGKPPKPYGGALGALGYQ----------GGGCFGKSCGRKRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54320-1", "uniprot_id": "ELN_MOUSE", "id": "P54320-1", "name": "Elastin", "aln": "MAGLTAVVPQPGVLLILLLN------LLHPAQPGGVPGAVPG--------GLPGGVPGGVYYPGAGIGGL-------------------------------------------GGGGGALGPGGKP---PKPGAGLLGTFGAGPGGLGGAGPG------AGLGAFPAGTFPGA------------------------------------------------------------------GALVPGGAAGAAAAYKAAAKAGAGLGG-------------------------------------------------------------------------------------------------------------VGGVPGGVGVGGVPGGVGVGGVPGGVGVGGVPGGVGGIG--------------------GIGGLGVSTGAVVPQ-----------------VGAGIGAGGKPGK-----VPGVGLPGVYPGGVLPGTGARFPGVGVLPGVPTGTGVKAKAPGGGG-AFAGIPGVGPFG-GQQPGVPLGYPIKAPKLPGG------------YGLPYTNGKLPYG-------------------VAGAGGKAGY---PTGTGVGSQAA--------------------AAAAK--AAKYG-AGGAGVLPG-------VGGGGIPG-----------------------GAGAIPG------------------------IGGIAGAGTPAAAAAAK------------AAAKAAKYGAAG-------GLVPGG------PGVRLPGAGIP----------------------------------------------------GVGGIPGVGGIPGVGG-PGIGGP---------------GIVGG---------------------------------------------------PGAVS-----------PAAAAKAAAKAAKYGARGGVG------IPTYG--VGAGGFPGYGVGAG--------AGLG-----------GAS-PAAAAA-----------AAKAAKYGAG--------------------------------------GAGALG---GLVPGAVPGALPGAVP-------------------------------AVPG-----------AGGVPG----------------------------AGTPAAAAAAAAAKAAAKAG-----------------LGPGVGG---------VPGGVGVG---------------GIPGG-----------VGVG-GVPGGVGPGGVTGIGAGPGGLGGAG-SPAAAKSAAKAAAKAQYRAAAGLG-----------------------AGVPGFG--------------------AGAG-----VPGFGAGAGVPGFG----------------------AGAGVPGFGAGAGVPGFG--AG------------------------------------------------------------------------------------------AVPG-------------------------SLAASKAAKYGAAGGLGGPGGLGGP--------------GGLGG--------PGGLGG-------------------AGVPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVAG--AAPPAAAAAAAKAAAKAAQYGLG-----------------------------GAGGLGAGGLGAGGLGAGGLGAGGLGAGGLGAGG-----------------------LGAGGLGAGGGVSPAAAAKAAKYGAAGLGGVLG-ARPFPGGGVAARPGFGLSP---------IYPGGGAGGLGVGGKPPKPYGGALGALGYQ----------GGGCFGKSCGRKRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15502-3", "uniprot_id": "ELN_HUMAN", "id": "P15502-3", "name": "Elastin", "aln": "MAGLTAAAPRPGVLLLLLS-------ILHPSRPGGVPGAIPG------------GVPGGVFYPGAGLGA---------------------------------------------LGGGALGPGGKP---LKP----------VPGGLAGAGLG------AGLGAFPAVTFPG--------------------------------------------------------------------ALVPGGVADAAAAYK-AAKAGAGLGG-------------------------------------------------------------------------------------------------------------VP---------------------------------------------------------GVGGLGVSAGAVVPQ-----------------PGAGV----KPGK-----VPGVGLPGVYPGGVLP--GARFPGVGVLPGVPTGAGVKPKAPGVGG-AFAGIPGVGPFG-GPQPGVPLGYPIKAPKLPGG------------YGLPYTTGKLPYGY--------------GPGGVAGAAGKAGY---PTGTGVGPQAA--------------------AAAAAKAAAKFG-AGAAGVLPG-------VGGAGVPG-----------------------VPGAIPG------------------------IGGIAGVGTPAAAAAAA------------AAAKAAKYGAAA-------GLVPGG------PGFGPGVVGVPG-----------------------------------------------------AGVPGVG-VPGAGI-PVVPGA---------------GIPGAAV-------------------------------------------------PGVVS-----------PEAAAKAAAKAAKYGARPGVGV---GGIPTYG--VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAA-----------AAKAAKYGAA--------------------------------------GAGVLG---GLVPG-----APGAVP-------------------------------GVPG-----------TGGVPG----------------------------VGTPAAAAAKAAAKAAQFG------------------LVPGVGV---------APG-VGVAPGV------------GVAPG-----------VGLAPGVGVAPGVGVAPGVGVAPG-IGPGG-VAAAAKSAAKVAAKAQLRAAAGLG-----------------------AGIPGLG--------------------VGVG-----VPGLGVGAG-------------------------------VPGLGVGAGVPGFG--AG------------------------------------------------------------------------------------------ADEGVRRSLSPELREGDPSSSQ----HLPSTPSSPRVPGALAAAKAAKYGAAVP--------------GVLGG--------LGALGG-------------------VGIPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVVG--AGP-AAAAAAAKAAAKAAQFGLV-----------------------------GAAGLG-------GLGVGGLGVP--GVGGLGG------------------------------------IPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP---------IFPGG-------------------------------------ACLGKACGRKRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1TQS2-1", "uniprot_id": "A0A8N1TQS2_DANRE", "id": "A0A8N1TQS2-1", "name": "Elastin", "aln": "MANRSVALLLLGFFLSVQLSPSLQGGVYVPQAGGGGAGPG-GAGVLPGAGLYPGAGSSP-YKAAKAAAG----------------GYG------------------------GAAGAGALGAGGYG--------------AGGYGGYGGYGGAGRFYPMAG-GLKPAKSGAG-----------------------------------------------------------------LPGGVLPGGVLPGGVLPGGVLPGGVLPGGGLPG--------------------------------------------------------------------------------------------------------GAGGKPPK--------GPGVGGAGTGLPGLGIP---------------------------QTGVQGLGPGGVGPG-------------------------AKAAKAGKAPVPGVGVPGPYQGG-LP--GQGFNGRGVLPGVATGTGLKPKSGGGQG-LVPGAGGRGPFGGPLQQGVFHGYPLKSPKAPG-------------AGLPYTGGKLPYG----YGGFGGGAGLP--GGKAGAGSKPGY---PTGTGVGSLG---------------------VSAAQAKAAKYGAGAGLG------------GAGAFPG--------------GVGAGLG--GAGAFPG-----------------------GAGGFYPGAVGTGGLTP-------------AQAKAAKYGAVP--GATGIGGLPG--AGGLFPGPGVGGAGALSP---------------------------------------AQAKAAKY---------GAGAVPGGAG--VLPGG-------------AGVLPGG---------------------------------------------------AGGIYPAPGG------AGALSPAQAKAAKYGAVPGG----AGVLPG-----GAGVLPGG-------------AGVLPGG-AGIVPGAGGVYPAPGGAGALSP-----AQAKAAKYGAGAVPG--GAGILPGGAG-----ILPGG----AGILPG--GAGILPGGAGIVPGAGGVYPGAGGAGALS-PAQAKAAKYG--------------AGAVPG---GAGILPGGAGILPG---------GAGIGPGGVYPG--------TGGAGALSPAQAKAAKYGAVPGGAGI-LPGG---AGILPGAGG--------VYPGAGGAGALSPAQAKAAKYGAGAVPGG----AGVLPG--GAGIVPG---RTGIVPAG---PGIVPGAGGVYPATGGLTPAQAKAAKYGLGAAG---------------------GAGAVPGVG--------------GLYPGAGGAG----VAPGYGSVAG---------------LGGQLG----------AGGLAAGAKPPKYGVPGG--------------------------------------------------------------------------TGFGVPG---------GVPG-GIPITG---PG------------GYPAGAKALKYGLGSGGLPAGTGVVPGLQRPGLG------GALGGAGTGTGYPFGGYG-----AGAKPPKYG-VPG---GVPG---GVPG---GVPG---GVPG---GYPAGVK--PPKYG-VAGGAGTVPG-AGGVP-----LAG------TGTGLAPG------AGVGGYPG----------GVKPPKTGAGIAGTGIAAPGAT--------------PGGTGIVVPGVPGGTGIAVP------------------SGTGVPILP----SGKPAKLPTLAPAG-TAVPGGAQRVPGAVPGGAYPYGSG-------------------------QYYGSAGPSG-VGTGVLPGAKPLKAPGVGGAGGVGGVGGLYPG----------------AGVGLGTGGVG---------TGAKPPKPGYGS---VGTGYAQPGGVAAGGYGAYP-----------GGYGAG------LSPQQAKAAKYGGGLTGFLGGG-YRGGAGCQGKYCGRRRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z3N0-1", "uniprot_id": "A0A8M6Z3N0_DANRE", "id": "A0A8M6Z3N0-1", "name": "Elastin", "aln": "MARRKVPLLLHGFLLLVLCRSSLQGGIYIPAGAGGGPGAGLGAGVGTGAGLGIGTGPGGGYGAGIGGAGPGVGPGGVGTGLGLGTGLGGLGTGTGIRPGTGAGGLGGIGPGGGGLGTGGLGTGGLGTAGLGTGPFVKPPKTGGYGGLPGIGAGGTGVGLGGLGLRPAGPGVGGLVPGGFGVGTGVGGTGTGVPAIGVGTGVGGLGIGGVGPGGAGIGVGGKPPKTGVSTGGIGPGGVVPGGIRPGGIVPGGVGPGGIVPGGVGPGGIFPGGVGPGGIVPGGVGPGGIVPGGVGPGGIVPGGVGPGGIVPGAGRKPGKPGYVGPGGGAGPFGTGTLGAGDPRFGAIPLTPGGTGTGYPSGGGYGGYGGPGGIYPGAAGQKPPKPGIGPGGTGTGLGGAGFGLGGAGVRPGGVGIGPGGTGIGSGGTGLGPGGTGVGTGGVGIGPGGTGTGGVGIAPGGSSFLPQTGLPGIGPGTGGKVGKPGKAPVPGVGIPGLYQGGIVP--GQGFGGRGVLPGVATGTQTGQLGQG-----ALGANGRGGFG-QQIPGVFGGYPLISPKSGGAAKSQAKAAKYGAAGVPGLGGGLGVGGVPGAGGITGTSGVPGLGGVPGAGTVPGIGSVPGAAGIPGVGGIPGAGGATPGGLYPGAGGIYPGGAGAKARKYASGVGTGGLPGSGVGLGGLGTGGLPGSGVGVGGLGTGGLPGSGVGVGGLGTGGLPGSGVGVGGLGTGGLPGSGLGGGGLGAGGLPGSGVGGGGLGAGGLPGSGISPEGYAAAKARKYAQLGRGGTLGTGGLPGGAAGVGLPGGGLGAGGQLGTGGLGTYGLPGGGLGGLPGGGAGGLPVGGIGGLPGSGTGYADAKARKYAQLGRGGTLGTGGLPGGTAGVGLPGGGLGAGGQLGGGLGTGGLPGGGLGTGGQLGGGLGTGGLPRGGLGTGGQLGGGIGTGGLGTGGLPTGGLGGLPGGGVGGLPGGGIGGLPGSGIGYADAKARKYAQLGRGGTLGSGGLPGGTAGVGLGGLPGGGLGTGGQLGGGLGTGGLPGGGLGGLPGGGAGGLPGGGAGGLPGSGIGYAEAKARKYAQLGRGGTLGTGGLPGGAAGVGLGGLPGGGLGTGGQLGGGLGTGGLGTGLGGLPGGGAGGLPSGGVGGLPGYAEAKARKYGLLGRGTGLGPGTGLAAGIPGGLPSTGIAPGGAGGLPGSGVGQGGIPGVGYGSGGAPSGGFGPGSVPGGGYGPGGISAAKARKYGIIAGAGGVGLPGGQLGSGTVPGVGAGGGTPVAGIGPGGVPVGGYRPGGVPAGGYGPGGVPAGGYGPGGVPAGGYGPGGVPAGGYGPGGVPAGGYGPGGVPAGG--FGQGSGAYPGGAKALKYGPGGSGGIPGLGLQGQVGTGPAGGLGTGAGQVGGFGPGTLGGPGSGFAGSGLPGSAVGAGSRGGLGPGYGTGAGGYGPGSKAAKYGLPGFGGALGTGALPGAGTGAGGYGGAQKLPKYGQPVGGVGSVPSGSVPATGGTGVTGTGISTGGTAIPLATGTDRGGLRPGVIGSPDGGTRGTGEAQGGTKAPKTESGGPVEGSGVTGGPIDTDGLYGVAGTGIPILAGERPGGTGVPRPEIGDSGTLPGAKPLKPPGTGGGAIAGRGDTPGTIEGGPGSIGSGIGGVGGGPGGVGATPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGGVPGGVGSGLTGTGGVKPPKVYGGAGGTGALGVGGVGGLGPAGGGGAGLLPGGGGLLPGGGAAGTGFGLQKPGKSYGGAGSLGAGGILPGTGIRFPSGAAVGSKPGKVYGAGTLGGLGGPGGYGAGPGGYGGGPGGYGSGPGSAGGLGGPGFGGLGYGPGGVKPPKSYGGAGALGGAGQGGIGGGPGRLGVGPGGAGGIGGGLGVGPGGVGGGPGGLGGGFGGYGGVGGGPGGTGGGLRYPGGAGAGKPGKAGFGTGALGGQGYQPGGSVPGYGTGAGPGAGYQQQYPGFGGPGAGGPGSAPLTPQQSKAAKY-AALQGFLGAGGYRGGAGCQGKYCGRRRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .. *.:* : : * ** .*. * .. : .. . .. * *.**.** ** * * . .* . . * : *** ... .*. ** * *:..*.. . * .* *****:** * ** :* * * * ******.**: * * * * ** ** ***: :** * *:* * * * .**. .* * .:*: . ..* * *:. . . * * ...** .*.:** **: .. .. . * *** **. * :** ** * *.* :** : * : *. * : . . * *** **. :* * * :** .* * . ..* *** **. *:* * * :** .. .:** :* :** .. . : *** . **.* ** .. .:. * * . * .. ** : .* . *** . .. * . : *.* *.* ** * ** * . . * :* * . * ..: .. * * :** *. * *:** * . * .. . . :* .*. * . . *.**:*. ..* .* * . : * .. * * * * .* ** ***:**", "identical_positions": 205, "similar_positions": 151, "identity": "9.69%" }, { "cls_id": "homologset.agr.HGNC:33270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCK4-1", "uniprot_id": "M0RCK4_RAT", "id": "M0RCK4-1", "name": "", "aln": "MLKRKISPVGEGEAMSPPKKSYTLDMVSNKSPEASAEAKGEGAIVSQKTQAEMMEGDPKVCAQNCAPKQCKPMAGDAILPSPRDSLPEDSLHCKDGDSTVTGARVSNDCSAGTAGVPALSSSEARRYVSSLKP-TVTNYEIKCALMTEIRRFGRQYGRLFEILEEVQGPLEVRIQFVEFSIKEAARFKRRHLIQYLEKMLEKLKSERSLNSAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DMU8-1", "uniprot_id": "CT455_HUMAN", "id": "P0DMU8-1", "name": "Cancer/testis antigen family 45 member A5", "aln": "-----MTDKTEKVAVDP----ETVFKRPRECDSPSYQKRQRMALLARKQGAGDS-----LIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSK-DGMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *:.* *: ..:. ..* : : . *::::* * : * .. .*: * *:*.** ** ** :* .. *. : . . ....:. : .. *.*. .** *. * :** *:.*:* .*::* ::**:** **** ** :*.* ****** **.::::*:* *::: ", "identical_positions": 57, "similar_positions": 66, "identity": "26.76%" }, { "cls_id": "homologset.agr.HGNC:33271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCK4-1", "uniprot_id": "M0RCK4_RAT", "id": "M0RCK4-1", "name": "", "aln": "MLKRKISPVGEGEAMSPPKKSYTLDMVSNKSPEASAEAKGEGAIVSQKTQAEMMEGDPKVCAQNCAPKQCKPMAGDAILPSPRDSLPEDSLHCKDGDSTVTGARVSNDCSAGTAGVPALSSSEARRYVSSLKP-TVTNYEIKCALMTEIRRFGRQYGRLFEILEEVQGPLEVRIQFVEFSIKEAARFKRRHLIQYLEKMLEKLKSERSLNSAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DMU7-1", "uniprot_id": "CT456_HUMAN", "id": "P0DMU7-1", "name": "Cancer/testis antigen family 45 member A6", "aln": "-----MTDKTEKVAVDP----ETVFKRPRECDSPSYQKRQRMALLARKQGAGDS-----LIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSK-DGMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *:.* *: ..:. ..* : : . *::::* * : * .. .*: * *:*.** ** ** :* .. *. : . . ....:. : .. *.*. .** *. * :** *:.*:* .*::* ::**:** **** ** :*.* ****** **.::::*:* *::: ", "identical_positions": 57, "similar_positions": 66, "identity": "26.76%" }, { "cls_id": "homologset.agr.HGNC:33273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ACD0-1", "uniprot_id": "A0A8I6ACD0_RAT", "id": "A0A8I6ACD0-1", "name": "", "aln": "MSVCTLSVPVSSISPGRRCSAFSDAGVLGCVSINSNTDEDGVLEGKMVAEGSNKETKLPAKKKRKKGLRIKGKRRRKKLILAKKFSKDLGSGRPVADAPASLASSAAEQDEESLFDGNIEKQIYLPSTRAKTSIVWHFFHVDPQYTWRAVCNLCEKSVSRGKPGSHLGTSTLQRHLQARHSPHWTRANKFGVTNGEEDFSLDLSLSPSSPGSNGSFEYIPTDSLDENRMGKKRDKSASDALRAKRGRFLIKSNIVKHALIPGTRAKTSAVWNFFYTDPQHISRAVCNICKRSVSRGRPGSHLGTSTLQRHLQATHPIHWAVANKDSGAIGNGLDETETESGDLLNDTLHG-EKSSGSQDLTAEDLSDSDDTDEPPVLEVENRSESPIPVAEQDNLAHTQERETTTDTHCEDAASSQISQAVIQMIVEDLHPYNYFSTPAFQRFLQIVAPDYRLPSETYFFTKAVPQLYDSVREKIFLTLENVQSQKIHLTVDIWTHDPSTDYFIVTVHWVSLETASSPSNGGTPNFRKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKGGGFTHVPCFLHCLNIVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKN-LKQDETGHWISTFYMLKWLLEHCYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQRVSVKTTGLNQVLPIIHHLLFSLQRLREDFQVRGITQALNLVDSLSLKLESDALLSAMLKSKHCILATLLDPCFKNSLEDFFPQGADLETYKQILAEEVCNYMESSPGACQIASSEASGPLVRLGTDSFTS-IKEGTSSAGSMDSSAADSVAIGSRSFLFPSAVAVVDEYFKEKYSELSGGDDPLVYWQRKVSIWPALTQVAIQYLSCPMCSWQSECMFTTNSHFHPKQIMNMDFDNIEQLIFLKMNLENVNYDYSTLILSWDPE-NKAVQNNEKEILP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D2EAC2-1", "uniprot_id": "ZBED6_MOUSE", "id": "D2EAC2-1", "name": "Zinc finger BED domain-containing protein 6", "aln": "MSVCTLSVPVSSISPGRRCSTFGDAGILGCVSINSNTDEDDVVEGKMVAEGANKETKLPAKKKRKKGLRIKGKRRRKKLILAKKFSKDLGSGRPVADAPASLASGAPEQDEESLFEGNIEKQIYLPSTRAKTSIVWHFFHVDPQYTWRAICNLCEKSVSRGKPGSHLGTSTLQRHLQARHSPHWTRANKFGVTNGEEDFTLDLSLSPPSPGSNGSFEYIPTDSVDENRMGKKRDKSASDALRAKRGRFLIKSNIVKHALIPGTRAKTSAVWNFFYTDPQHISRAVCNICKRSVSRGRPGSHLGTSTLQRHLQATHPIHWAVANKDSGAIGNGLDETETESSDLLNDTMPG-EKSSGSQDLTAEDLSDSD-TDEPPCLEVENRSESPIPVADQDNPVHAQERETT--THCENAAANQISQAVIQMIVEDLHPYNYFSTPAFQRFLQIVAPDYRLPSETYFFTKAVPQLYDSVREKIFLTLENVQSQKIHLTADIWTHDPSTDYFIVTVHWVSLETASSPSNGGTPNFRKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLTPSFIVSDNSSNVVHAIKGGGFTHVPCFLHCLNIVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKN-LKQDETGHWISTFYMLKWLLEHCYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQRVSVKTTGLNQVLPLIHHLLFSLQRLREDFQVRGITQALNLVDSLSLKLESDALLSAMLKSKHCILATLLDPCFKNSLEDFFPQGADLETYKQILAEEVCNYMESSPGACQISSSETSGPLVRLGTDSFTS-IKEGTSSAGSLDSSAAGSVAVGSKSSLLPAAVAVVDEYFKEKYSELSGGDDPLVYWQRKVSIWPALTQVAIQYLSCPMCSWQSECMFTTNSHFHPKQIMNMDFDNIEQLIFLKMNLENVNYDYSTLILSWDPE-NKAVQSNEKEILP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86452-1", "uniprot_id": "ZBED6_HUMAN", "id": "P86452-1", "name": "Zinc finger BED domain-containing protein 6", "aln": "MSVCTLSVPVSSLSPGRRCNTFSDSGILGCVPINSNTDEEDVVEEKMVAEGVNKEAKQPAKKKRKKGLRIKGKRRRKKLILAKKFSKDLGSGRPVADAPALLASNDPEQDEESLFESNIEKQIYLPSTRAKTSIVWHFFHVDPQYTWRAICNLCEKSVSRGKPGSHLGTSTLQRHLQARHSPHWTRANKFGVASGEEDFTLDVSLSPSS-GSNGSFEYIPTDPLDDNRMGKKHDKSASDALRAERGRFLIKSNIVKHALIPGTRAKTSAVWNFFYTDPQHISRAVCNICKRSVSRGRPGSHLGTSTLQRHLQATHPIHWAVANKDSGAVANGLDEAETERSDLLSDTLHG-EKSTGSQDLTAEDLSDSD-SDEP-MLEVENRSESPIPVAEQGTLMRAQERETT---CCGNPVSSHISQAIIQMIVEDMHPYNYFSTPAFQRFMQIVAPDYRLPSETYFFTKAVPQLYDCVREKIFLTLENVQSQKIHLTVDIWTHDPSTDYFIVTVHWVSLETASFLNNGRIPDFRKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKDGGFTHVPCFLHCLNMVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKN-LKQDETGHWISTFYMLKWLLEHCYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQKVSVKTAGLNQVLPLIHHLLLSLQKLREDFQVRGITQALNLVDSLSLKLETDTLLSAMLKSKPCILATLLDPCFKNSLEDFFPQGADLETYKQFLAEEVCNYMESSPEICQIPTSEASCPSVTVGADSFTSSLKEGTSSSGSVDSSAVDNVALGSKSFMFPSAVAVVDEYFKEKYSEFSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMNLKNVNYDYSTLVLSWDPEQNEVVQSSEKEILP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM61-1", "uniprot_id": "Q9VM61_DROME", "id": "Q9VM61-1", "name": "BED-type domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKKSNVWQYFYKTSG--TVATCLLCNRNYSRRGRG----TTCLRNHLKSKHPPEFLSLSGDIKYLDLVKSEISIGSPQHPTAQLELNLHETDSDPLDTEDISYSKRCDEKLALMLLN------------------------------------------------HSFEFIEGPGFVNFIRTLQPRYTIQPRSYYEKILCEDIQRKMHQHLKQQVDLLD--AISLSTSLWRGDKGEGLLSLSCSGISRDFQTHRLMLKCEALNYESTSKLACCIRDLVPSLAIEVPKEKIHCVIR---------------DEMTALPG---SLPDCSVHRLQMCVRFALQSNELLQNLSSKCKQIVDHFASSKMANDHLKFIQEIRLTRDPCTLTPYDPCQWNSAFQMMSSVFRMKDALSLYCEEYSLVQIYPDEWIEIDLCSKVMQPCEETIKIWSNPSTTTSSVIPLVAALRDSLRTDVHNFVSSVTICSF----ARKLLEELEMKFAHITSDINFLMATYLDPRYK---QAFFTE-----REEQLVANEVLLQLAGVPEDCNG---QPPLKIIKVSSTSSQKNESKIDSILDSILTTGTTNTQQPNTSMGSQSQIKNLLYLYNSE-PRIDRNMDPLIWWRSNIKYIS-LYGIVRKFLSAPAASVVSEGLFRKSTHLYFDMQAGLSPESASKMLLMKANFSFSNSEIN-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* **::**. . : *.* :*:*. ** * *: *:.**::.** .: . * : .* . : . : :.:.*: * :**:* *. ** * : * *.::::. *.* .*:: : * * : ..:*: . :: ::::: :: :: * *:..:* * . . : :: :* : : :. :. :: :* : : :: :::* : : : *: . : * :* *:: :: : .:: ::*: .:: .**: * *.: *: :*: : *. :. :* *:* *:. ::. :: . * * : . :* : ..:::* **: : * :: ..*:*:: * **: .:* :: : .* * : :: : .. ::** *** :* : **.: :*::*:** : . * *: :.. : :.: * . .: * .*: ::.. .. . * : : : ::.: ..:. . ***::*: ::. . * :. ::**.* .* ** :* ..:*:: . .:. :. .:::::* *:. * : . ", "identical_positions": 110, "similar_positions": 240, "identity": "11.14%" }, { "cls_id": "homologset.agr.HGNC:33274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1J3-1", "uniprot_id": "D4A1J3_RAT", "id": "D4A1J3-1", "name": "", "aln": "MALQTPVLSPATPTVMAESALYRQRLEVIAEKRRLQEEIGAARRELEEEKFRVERLKRKSLRERWLMDGAAEGPERQEDPASKDPESPEGQAQARIRNLEDSLFSLQSQLQLLQSASTGAQHRPAGRPAWRREGPRPLSQPAMDTGPTGPTDVDKRTSLPDAPVGISSESPSDPREESIGVLPALRPSPEAIGTSSEANGPCPGHSSLPEQ-LSLGVSS----VTKAKGDGVVEVVWAGLRATENSATGPTGVELEAKVEEVVLEAIGARQGTSSPDLPTWVKEGRGVVEVVWEGLGGRDLDVTEESGSGAEAMHTGTPRLQEQFESETCRKEEGASRDSLEGVGQGGPGAEEGSFIWVEKVALSEDWEEILMEGLEAPPEAGSARGPEALMGAQ---PRGDESSWEVEKREVEKMEGREEKGRAEKLGAELEDGAAVLPDATQGGEESEAEKIERKDGEGPFPEEIATDEEKWEVKEKKDEEPLEVEKGGEEEPPTIEKPLVAEKEAEGSPETEKKGNETPLGQEKDGEGSLDRESK-TEILLDGETGGESSLDETKGSKKLLDEETGGEGSLDEATKGSKKLLDGEAGGSELFSEVEKTSGAKDDVSPEEQGKSNEGADFQAEEASQPGATLCVQEEPRSEEQGLQDPEKQESPVEEATRKPQPCTESEGPPEDATPLLAETPAPEQPVESQPLLRQEVSSTNPGDHPAPTYAPAPQLEL---AEVKEASGPKQKTCQCCVVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2TJV2-1", "uniprot_id": "PALM3_MOUSE", "id": "A2TJV2-1", "name": "Paralemmin-3", "aln": "MALQTPVLSPATPTVMAESALYRQRLEVIAEKRRLQEEIGAARRELEEEKLRVERLKRKSLRERWLMDGAAEGPERPEEPASKDPQSPEGQAQARIRNLEDSLFSLQSQLQLLQSASTGAQHRPAGRPAWRREGPRPLSQSAMEAAPTAPTDVDKRTSLPDAPVGMSPESPSDPREESIAVLPASRPSTEAIGTSSEANGPCPGHSPLPEQ-LSLGVSS----VTKAKGDGAVEVVWAGLRATENSATGPTDVELEAKVEEVVLEAIGARQGTSSPELPTWVKEGRGVVEVVWEGLGGRDLDVTGESGRDAEATHTSSRRLQEQFEAETCRKEEGASRDSLEGVGQGGPGVEEGSFIWVERVALSEDWEEILMEGLEAPQGAGSAGEPEALIGAQ---PRGGEASWEVEKREVEKVEGIEEKGRAEKLGAEREDGVAVLPDETQGREENEAEKVERKDSEGPFPAEIATDEEKWEVKTTEGEESLEVEKGGEAEPVTTEKPLVTEKKPEGSLETERKGSEMPLDQEKDGEGSLDRESKTTEILLDGEIGDKSSLDETKGSKKLLDEKTGGEGSLDEEAEGSKKLLDREADGIEPFSEVDKTSGAKDDVSPEEQGKANEGAEFQAEDASPPGATVCVQDEPRSEEQGQQEPEKQEGLVEGAASKPEPCTEREGPPGDATLLLAETPAPEQPVESQPLLHQEASSTNPGDHPAPTYAPAQQLEL---AEAKEASGPKQKTCQCCVVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NDB9-1", "uniprot_id": "PALM3_HUMAN", "id": "A6NDB9-1", "name": "Paralemmin-3", "aln": "---------------MAESSLYRQRLEVIAEKRRLQEEIRAARREVEEEKLRVERLKRKSLRERWLMDGAAAVPEPSEDPTSKDPQSPEGQAQARIRNLEDSLFTLQSQLQLLQSASTGAQHKPSGRPSWRRQGHRPLSQSIVEAGSVGQTDLNKRASLPAGLVGTPPESPSEPREDVLGFLPGPRQVPGAAGDSSEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGGGVVSVVWEGLRATEDCATGATGPELEAKVEEVVLEAIGDRKGAGSLELPAWVKEDRGIVEVVWEGVGGSDAEAMGEIGRVPEVVQTSSPRLQERLEAAASIEGEDVPQGSPEGDGQGGSGGEEGSFIWVERVTLSEEWEELLVEGLEGPEVAGRERGDESPLGAEGAKTGGGEETWEAEKRKAEESMG---IGSEEKPGTGRD-------------EAEMSPVVERKGGE-----------KKLELESRGSAEKLGTEREGGEEPLGIERKVEGHLRAEKEGDEEKRGAE-----EEEVEEPLGVEKK----------GGEEEPEATKEP--LEAERKGGEETLEAEKRGG-----------EESLETEKTQGTEGDLNLE-QG-SREGSESQAEEMNEAGPPLEANTETRPEKEGPQPQEKPVGALEEEGVKPQTAAEGQGPLGDATPLLAETPAPEQPAECQPLLQGEGPSANPSAHPVPTYAPARQPEPSAPTEGEEASGPKQKTCQCCAVM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:******************* *****:****:******************** ** *:*:****:******************:*****************:*:***:***:* *****. :::.... **::**:*** . ** ..****:***: :..**. * . * * *********. . *** ** . . * :***.*.*.*** ******:.***.*. *************** *:*:.* :**:****.**:*******:** * :. * * .*. :*.: ****::*: :. : *...:.* ** ****.* *********:*:***:***:*:****.* ** *: :**: . *.* :**.***:.*: * * ** *: : * . : :***..* :* *:: . * * .*: * ** *: : . ..* . : *::* * *:: * .*. *.* *.:.. : ** . * *..*** :*: .*. * *.:**.*::.*:. * ** :.**:: ***: . .*..: .: *.*.*::* * ** . :* **:..:* :** *** ***********.*.****: * .*:**. **.****** * * :* :*************.**", "identical_positions": 366, "similar_positions": 167, "identity": "49.13%" }, { "cls_id": "homologset.agr.HGNC:33276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2VIS4-1", "uniprot_id": "FILA2_MOUSE", "id": "Q2VIS4-1", "name": "Filaggrin-2", "aln": "MAYLLRSVVTIIDVFYKYTKQDEECGTLSKDELKELLEKEFRPILKNPDDPDTVDVIMHMLDRDHDRRLDFTEFILMIFKLALACNKVLGKEYCKASGSKKHRRGHQHQEEESETEEEEE-TPRQKSGFRFSSWSEGEEHGHSSGGSRGPAKHRRGSNSKRLERQDELSSS---EESRKKHHGSIFGHSWSSNKEKDGSRSEELGEKGDKSYDSPSRESEEEYESGYRLNHQGREGHSGLSCGLEKNKYELNYIQLRKGGEQKLGYNTSSSGNSKIQSHVYGFSNSSGCCRPKNASSSCQASRSQGQGNQSCRTQSNCQSGTSGGQGYGCVSEGQSSRCCQPKPRSCSQSSSQRGYGSKQCGQPQNCGRQQRMGSSHSSCCGPYGSGATQSSGCGQQRMSSCGHSSSSHQKGCSSNGFSKGDQRASGSGHSSCCEQHGTNSSQSSGFKQHGHESGQSCCGQHGTASSQSSGYSQHRVGSGQSCHYGQHGSSSGQSSSSGRHGSGSGQSSSSRHNRSGSSQSSGLEEHGSSSHQSHSSGHHGSGSRQSSGSEQHGAVSGQSSGS-----------GKHETGPSQSSSSGHHGSGSQQ------HGGGSGQSTGFGEHES----------SSGHSSSSGQHRSGSRHSSGSGKHESGRSQSSGSGHHGSGSQQ-------------------------------HGGGSGNSTGFGEHGSSSHPLPSSGQNESSSGQSSRSERHGTGSGQSSGFGQHGSGSHQSS-----------------------SSGHNEYGSGQTSSSWPHGKGSGQESGYGEQESGHGQSSSSWQHGTGPGQSSSSEEEESRPGQSSSSWQHGKGSGQESGYGEQEAGHGQSSSSWQHGTGAGNQSSGYGEHKSGPSHSSRSWHHGTGSGQSLGFGQHGKGSHQSESSGHYESVSEPSSSSWQHGNGSGESYGYGEHESGHGQSSSAWNHGNESGQSNGYGEHESGHGQSSSAWNHGNESGQSNGFGENESGRDQE-GYQQRESFHGQHRHPLSQHEQHSQFGYGRSPRSPVHPESSEGEEHSVVPRRYSGYGHGQGQAGHQQRESGYGQRGRPQGPSQDSSRQPQAGHGQPSQSGYGRSPRRSQVHPEYSEGEAHSEVSQRHSGSSHCHCHCHGQARHQQR--ESVHGQRGRPQGPSQDSSRHPQAGPGQPSQSGSRRSPRSQPVHPESSEGEEHSVVPQRHSGSGHGHGQGQGQAGHQQRES---VHGQQGRPQGPSQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGHG--QGQGQGQAGHQQRESVHGQRSRPQGPFQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGHGQGQGQAGHQQRESVHGQPVRPEVPTQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRNSESCHCHCHDQAGHQQRES---VHGQRGRPQGPSQDSSRHPQAGPGQPSQSGSRRSPRSSPVHPESSEGEEHSVVPQRHSGSGHGHGQGQGQAGHQQRESVHGQRGRPQGPTQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGHGHGQGQGQAGHQQRESVHGQRGRPQGPSQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRYSGSGHGHGQGQAGHQQRESVHGQR-GRPQGPSQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVIPQRHSGSGHSHGQGQVHAEHQQRES-VHGQRGRPQGPSQDSSRQPQAGQGQPSLSGSGRSPRRSPVHPESSEGEEHSVVPQRHSHSESGHGHGQGQGQAGHQQRESVHGQRGRPQGPSQDSSRQPQAGQGQPSQSGSGRSPGRSPVHPESSEGEEHSVVPQRHSESGHGHGQGQGQAGHQQRESVHGQRGRPQGPSQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGHGQGQGQAGHQQRESVHGQPVRPQGPSQDSSSQPQASQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGHG-QGQGQAGHQQRESLHGQRGRSQSPFHPSHSIHWQSKCTISKKSSRLSGHYGRNHFQSTISGNQYDSSQSSRHGSYGPQDYDYGQSGYGPSGRLRSNSQSSIPFSSAHRATNMEVLPCGQSFSPSDHVGTKANEQIGELVFKYRESETGPDQSVDYYNLTESNSTTRG-HECSHGHSVVVPEHSDDSDFNYGHSYNGKQQICQSQPTVQSCFDDSQYILFQKHLESPSFGNQSGFSPNERQLYTCNESIDSYHLSSDSNNRNQIYSSNNSFPNLYCIGTEQCIYLPSATILGEGTEGQEPGYTQPGTICKYNQFLDGRKSRTRGNHETGKMKSGSAYLDSNTPLYTYVQEQKSYYFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5D862-1", "uniprot_id": "FILA2_HUMAN", "id": "Q5D862-1", "name": "Filaggrin-2", "aln": "MTDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKELHPVLKNPDDPDTVDVIMHMLDRDHDRRLDFTEFLLMIFKLTMACNKVLSKEYCKASGSKKHRRGHRHQEEESETEEDEEDTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIR-EQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNS----SSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQ-TCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYG-QHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSS-YGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSG-QYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQS-SYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSN-YGQHGSGSSQSSGYGQHGSSSGQTTG-FGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRS----RQSSYGQHG--SGSSQ-SSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQH-ESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRG-------DTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESE-STVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHR--PQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSG--HTHGQSGSQHGESE-SIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEE---PEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTG--HTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSG----HTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRP-HSR-GHTHGQAGSQHGESE-SIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGG--SHTHSGHTHSQARSQHGESE-STVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSG--HTHGQ-AGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQS----TQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQ-GTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAH---YGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAG-SQQRQPGSTVHGRLETTHGQTGDTTR----HGHSGYGQSTQTGSRSSR---ASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLSWSTDSTANKQLSRH----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *******:*********** *******.*********::*:******************************:******::******.****************:**********:** ** :***:*.**********:*** ***..* *:****:** **.:**** * *:*::* * *****..*::.** * ** *: :**: ****** ****** * *:**.*******.. :* * * * ***** . *.**:* :**. *:****** **:*******: * ***** . **.**** .****:**** **.* * **:...**** ******::: ******* * * ***:***** ****.:**.. **:. .***: *.* .*** *** ** .***.:*:. *****. ******:** *** **** ::**** **.** .**::. :*****.*****. *: ********. :: * *.****: :*** * ** . *:* * ***** . ***: *.**** *:* *..**:. *::**** * **.*****:***:*** *** *.*** : ***::** *:* ** ***:* *::**** * ** **.:*:*:*:***** .. **:* ****** :**:*************** *** ***:.::** ***. **.**.*.:*:*: ** ***:. ***:*.****. :.***. *** ***.**.*.****:: :. **:*. ** :.:* * **:*:* **..:** :******* ***** . **** * *:: * *. **. ***..**:::*:*:*.** ****. :**. ****.*:*:**** *:**. :* ..*.*** :*:: ** .*. ** *: * ** :.**.. * * . :.. :** :*.. . : **:*: :.:: *:*.***:* .*.** ** * * .. . **:*: * . :.: : * *. .. . :. * *:*: * :* :**:* .. *....:* ::*.* .:. *.: * .: . . .:. . . : *** *:. * **. ** ** ***:* .:* : :::*:.*:****.:*:** : ** . :.*.*:.* ** *.:*** * :. : .*.: :::: :.****. *::*: ::*:**.:*:** * *: *.::::.* ** *.:* .. : *.*. .* *..: .:** : . * ::: : ::*:**.:* ** : **.. *.***:.* ** .:* ..: : *.*** *: ** ***::* .:* : *::**.: *:.:* ** : * .. *.***:.* ** .: *** * ***. .* *..: . :*.:: .:* * *::*:. :*: *.:*:** : *: . *.**::.* ** .:* . * :*:. .* : . :** ::* .:* *:: :.::*:**.:* ** : *: . *.***:.* ** *.: ::* * ***. : * * **: :* * .:* : *::*:.: :* .:*:** : **.. *.* *:.* :* :.: *** * :**.:::* : ** ** ::* :* : *::*:.::*:**.: :** : ***. *.* *:.* ** ..** **. ** ***. .* *..: . *. ::* .:* : *:* :.*:*:**.:****. : * . *.***:.* ** *:.*** *.*.:.* *..: .:** :: .:* : *::.: :..:**. *:** : **.. *.* *:.* * *.: *** * *** *. :. .*** : .:* : *:: : ::.:**.:* ** : **:. *.* *:.* ** *.: *** .**:. . :*::* . :* :*:: .. : :** * ** :::.** :*: * .* :*: * : . *:: :** ::*:** . ** .. :.. :: * :. . * :.. : .::::.. .*: : :.:* :* . :*.*: :* : :**:: ...*:. :.**:* : .: : : :* .**: : .* .* : .*:* * :.: * : ::: * .:....* .:..: : *:... :: : ...:* *. * :* . .*. . * .: . ..::*. .* : * .: ", "identical_positions": 989, "similar_positions": 717, "identity": "40.17%" }, { "cls_id": "homologset.agr.HGNC:33277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z988-1", "uniprot_id": "D3Z988_RAT", "id": "D3Z988-1", "name": "", "aln": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPAATTSFSQKSPQARALCRSCSHYEPPTFFLQEPEDDDFEGVRNGGGRVAYKSISQEDVELPSASFGGLQALNPNRLSAMREAFSRSRSALPWSSRRSKCPHEGAFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUM6-1", "uniprot_id": "F163B_MOUSE", "id": "Q8BUM6-1", "name": "Protein FAM163B", "aln": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPAATTSFSQKSPQARALCRSCSHYEPPTFFLQEPEDEDFEGVRNGGGRVAYKSISQEDVELPSASFGGLQALNPNRLSAMREAFSRSRSVSTDV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C2L3-1", "uniprot_id": "F163B_HUMAN", "id": "P0C2L3-1", "name": "Protein FAM163B", "aln": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPTASTSFSQKSPQARALCRSCSHCEPPTFFLQEPPEEE-EDVLNGGERVLYKSVSQEDVELPPGGFGGLQALNPNRLSAMREAFARSRSISTDV-------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************************************************************:*:******************* ********** ::: *.* *** ** ***:********...*******************:**** . ", "identical_positions": 145, "similar_positions": 12, "identity": "80.56%" }, { "cls_id": "homologset.agr.HGNC:33278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKZ5-1", "uniprot_id": "A0A8I6AKZ5_RAT", "id": "A0A8I6AKZ5-1", "name": "", "aln": "MGPGLGQQLGNLHHIFQVRNNLQGMSGNSLLGSCDLKDGY-VGTSETISMNQISATGSPSSFQDIRAPDTRAPSVANLHFTLEAFECLSASQVGRLWEQVRQFWADHFSRRFSPRRPPLRHISSTSTFYLLDYRTRQAELGLSYGAPRTRLSDEAFVFRGGRWTAEGKGARARTSLPSPTTPTWKPQGQPIKSQVLLEENNYLKLQQELLMDMLTETTARMQLLEKKVATDDDPAAPARSWKRKIHKHEG--AGVLIVQPRALESR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CVN6-1", "uniprot_id": "CBY3_MOUSE", "id": "Q9CVN6-1", "name": "Sperm annulus positioning complex subunit Chibby3", "aln": "-------------------------MADSKMKWGQAWDSS-LGTATTSSS---SATGSPSPFQNIRVPDTRAPRVAHTTFTLEAFECLAASQAGRLWKQVRQFWVDHFSRRFSPRRPPLRHISSMSTFYLLDHRTRQAELGLNYGEPRTRLSDEAFVFRGGRWTPEGKRASARTPLPSSTIPAWKPQVQPIKSQVLLEENNYLKLQQELLMDMLTETTARMQLLEKKVDADNNPAAPARSWKRKMPKQRG--AGVLIIQPRALESR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NI87-1", "uniprot_id": "CBY3_HUMAN", "id": "A6NI87-1", "name": "Sperm annulus positioning complex subunit Chibby3", "aln": "-----------------------MWASRDHLPEPDLGDAAPPGSPSSFWTSGLPRQERSTSRQRSRGSPS-STCVPYKVHALATFECSATSHASRLWQTLQQFWADHISRPFSPRRPPLRRMPSLSTFYLLDHNTRQAELGLAYGAPCMRLSNQAFVFRGGRWTTESQLARTRSPLLSRTAWGWKAQVQRSKSQVLLEENNYLKLQQELLIDMLTETMARMHLLEKQRNPEVIPTAAARAGQRKMRKRAGASAGVLMIQPCALDSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B9A0M5-1", "uniprot_id": "B9A0M5_DROME", "id": "B9A0M5-1", "name": "", "aln": "-------------------------------------------------------------------------------MQLATFCCPSSISDSQPLPFKQLFAMPLFNKKFESKPIPVRQGRCN-----IGHPVATEDLD-DFRQISLTLGNKELRFADGIWMHSTRKGDVDDMLR-----------LNKKFRALEEENNMCNLKIEVMLDLLAEHATELSELKPKEK-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* * :: .: : * :.: *..: *:*: . :.: . :*. : *.:: : * .* * . : . . * * :.* **** :*: *:::*:*:* :.: *: : ", "identical_positions": 25, "similar_positions": 45, "identity": "9.4%" }, { "cls_id": "homologset.agr.HGNC:33279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBC4-1", "uniprot_id": "D3ZBC4_RAT", "id": "D3ZBC4-1", "name": "", "aln": "MKPVHERSQECLPPKKRDLPVT--------SCSTNHTPSSD--------------------ASEWSRGVVVAGQS----QTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPY--SLPYAVPPNFLPNPLLSPSANLATTHLPHFVPYASLLAEEAAPP-PQAASPAQSFTKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQTSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANG-QRQRERS-VRRESEPLDSTSSKGESQGLVPVVECMVDGQLFSGSQTPRVEVAAPTHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDE-PSPLNLS---HHTLDHQGEGR-GSARNPTEVVEKNQTRV---------------------FYPQSHQEPVKHRPLPKAVVVANGNLVPTGTDPSLLPVG--SEILVASSLDMQARATFPDKEP---TPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQ-WPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNS--------------VSQASCAPPGQLGTPR----ERPERTILGPRDLCDSEGKNQTSGEGSRVGEPSQPE-------------------------PSAQACWPAPSFQRYSMQGEE------ARAALLRPSFIPQEVKLSIEGRSNAGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7T6-1", "uniprot_id": "ATX1L_MOUSE", "id": "P0C7T6-1", "name": "Ataxin-1-like", "aln": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSD--------------------ASEWSRGVVVAGQS----QTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPY--SLPYAVPPNFLPSPLLSPSANLATTHLPHFVPYASLLAEEATPP-PQAASPAQSFNKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQMSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANG-QRQRERN-VRRESEALDSASSKGESQGLVPVVECMADGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDE-PSPLNLS---HHNLDHQGEGR-GSARNPTELVEKSQARV---------------------FYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDPSLLPVG--SEILVASSLDLQARATFPDKEP---TPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQ-WPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNS--------------VSQASCAPPGQLGTPR----ERPERTVLGPRDLCDSEGKNQPSGEGSRVGEPSQPE-------------------------PGAQACWPAPSFQRFSMQGEE------ARAAMLRPSFIPQEVKLSIEGRSNAGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7T5-1", "uniprot_id": "ATX1L_HUMAN", "id": "P0C7T5-1", "name": "Ataxin-1-like", "aln": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSD--------------------ASEWSRGVVVAGQS----QAGARVSLGGDGAEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPLHYAQLPSTSLQFIGSPY--SLPYAVPPNFLPSPLLSPSANLATSHLPHFVPYASLLAEGATPP-PQAPSPAHSFNKAPSATSPSGQLPHHSSTQPLDLAPGRMPIYYQMSRLPAGYTLHETPPAGASPVLTPQESQSALEAAAANGGQRPRERNLVRRESEALDSPNSKGEGQGLVPVVECVVDGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKEE-PSPLNLS---HHTPDHQGEGR-GSARNPAELAEKSQARG---------------------FYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDSGLLPVG--SEILVASSLDVQARATFPDKEP---TPPPITSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQ-WPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTTQLFSLPCHRLQVGDVCISISLQSLNSNS--------------VSQASCAPPSQLGPPR----ERPERTVLGSRELCDSEGKSQPAGEGSRVVEPSQPE-------------------------SGAQACWPAPSFQRYSMQGEE------ARAALLRPSFIPQEVKLSIEGRSNAGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB74-1", "uniprot_id": "E7FB74_DANRE", "id": "E7FB74-1", "name": "", "aln": "MKPVHERNQECLPPKKRDLPVNNNNNNTSINTNSNSSSSISGGAGGSGIGPGGAGGGGEDAPSSQSSGANAESQSSEWVRAQTGVHYGVESAEGLVGLPVDQYSMLYKVALPTGTYSPTSLHPVLTH-----AYTVPSPMLQHTSVPYPPT----FPHSSLQFVNPPYPTAVPYAVPPGFVPSSLIPPQSGIS---QPHLVPYPSVIQEGVVSSQPQPQVSSHAYTKMLAP------LVLSSEQAATQVPIGTVGMLPTGELSPRGVPVFYHPAVRG----VQSHSSSLEQDREVNG----GDRDHGGRESHQDAVYSARSVRLMQTTVLEPQQDKSLKSRRPEGR---MSPGQSSTPDTDLEVQQVVGRLASP---VHGSSRKDASHVPLNLSQSSQRSRETQGEIRTAYALNPAESRAHQQQIVQQGHAVILANGQPVLVPLDYHHHHQQQQQPQQHHYQPNDVASAAIVASPATYTKAMDAAACLPERAVAEPPPQQGQQVISAPAPGAFPQAPLLAPTGPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEMSGGLKIDSSMVVDIRASQQRPGLVALHFNVGEQQSKVTIDVPPEHPFFVYGQGWSSCSPERTAQLYGLTCHHLQVGDVCVSVTLQQQAASQQKPPQQVQARTPTKANSTSGATPQPMGPPAPQHTPRPQSHLKIHREREHNKEEPMQIGGSRHIDMPPRPNRTSAEHTHSQSNYYLHTEGHAPGVGAASQRRWSAPGFQRYSIKNEDGRLVSAATSGSSRPSFIPQEVKLSIEGRSNAGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3V7-1", "uniprot_id": "Q9W3V7_DROME", "id": "Q9W3V7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQMHMELSYGRGYDPIGRQPPSLPPPSQQHWSSNGFSDDSA--------------SCFRRGSYIELASGAMRRVEDIRTEDFIQSALRSQLFELREATVVRIDWSG-CPSLVTLTFSYDTHHAKMDLQVQPGHPMFVYGQGWASCDPQLSLQLYELKCQQLQVGDICLSLVPNEQPAAP---------------CPPQPAPPPPCPPPS----------------LPPSMEMPVPMGS------------------------------------PPTGSYGFLPFKHPYEMYAQM-------------ASFVAVYTQHMMGKLNY---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . . :. . * * :*: *:**:* ::****::*:**::** * ::: .: ** * * *.:* * * . :::*: ::* * **:*******:**.* : **: * *::*****:*:*: :. : .. *.* .* . * . : * : :.: : .**:. .: : . ", "identical_positions": 58, "similar_positions": 67, "identity": "7.28%" }, { "cls_id": "homologset.agr.HGNC:33280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DA97-1", "uniprot_id": "SEP14_MOUSE", "id": "Q9DA97-1", "name": "Septin-14", "aln": "-MAEKPTNTSVPIPGSEDPQKEN-IRCLSTLGHFGFECLPTQLVN--------------KSIQKGFSFNILCVGETGIGKTTLINTLFNTNLKE---------TKSSHFYSKVGLTVKTYELLERNIPLRLTVVKTVGYGDQINKEASYQPVVDYLDAQFEAYLQEELKIKRSLADYHDSRIHVCLYFITPTGHSLKSLDLLTMKSIDRRVNIIPLIAKADSLSKNDLQRFKNNIMSELNSNGIQIYQFQVDDEA----SAQVNS--SGLLPFAVVGSMEEVKVGKRMVR--GRHYPWGVLQEVENENHCDFVKLRDLLLSTNMEDLKDQTHTQHYECYRSNRLQK--LGFSDTGPDNRPVS--------------FQEMYEAKRREFHNQCQKEEEELKQTFMQRVKEKELTFKDAEKELQDKFEHLKRIQQE-------------------------EILKLEEERRKLEEQIIDFYKMKAASESAQAQVCTNIKKDKDRKK---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2Q660-1", "uniprot_id": "A0A1W2Q660_RAT", "id": "A0A1W2Q660-1", "name": "", "aln": "-MAEKPINTLVQTPGSEDPENEN-IRCLTTLGHFGFECLPTQLVN--------------KSIQKGFSFNILCVGETGIGKSTLINTLFNTNLKE---------AKSSHFYSKVGLKVKTYELLERNIPLKLTVVKTVGYGDQINKEASYQPVVDYLDAQFEAYLQEELKIKRSMPDYHDSRIHVCLYFITPTGHSLKSLDLITMKSIDRRVNIIPLIAKADSLSKNDLQRFKNNIMSELSSNGVHIYQFLADDEA----TAQVNS--SGLLPFAVVGSMEEVKVGKRMVK--GRHYPWGVLQ-VENENHCDFVKLRDLLLCTHMEDLKDQTHTQHYECYRSSRLQK--LGFSDKGPNNKPVS--------------FQEMYEAKRQEFHDQCQREEEELKQTFMQRVKEKELTFKDAEKELQDKFEHLKRIQQE-------------------------EILKLEEERRKLEEQIIDFYKMKAASESAQAQPCFQRSPREAGAKESCPTGSGRGERVLAASCVRTSGAVVKRQPKITPLAANPIQFHAPPSALPLRVRAPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZU15-1", "uniprot_id": "SEP14_HUMAN", "id": "Q6ZU15-1", "name": "Septin-14", "aln": "-MAERTMAMPTQIPADGDTQKENNIRCLTTIGHFGFECLPNQLVS--------------RSIRQGFTFNILCVGETGIGKSTLIDTLFNTNLKD---------NKSSHFYSNVGLQIQTYELQESNVQLKLTVVETVGYGDQIDKEASYQPIVDYIDAQFEAYLQEELKIKRSLFEYHDSRVHVCLYFISPTGHSLKSLDLLTMKNLDSKVNIIPLIAKADTISKNDLQTFKNKIMSELISNGIQIYQLPTDEET----AAQANSSVSGLLPFAVVGSTDEVKVGKRMVR--GRHYPWGVLQ-VENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQK--MGFTDVGPNNQPVS--------------FQEIFEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQE-------------------------EIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTDTKKDKHRKK---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54359-1", "uniprot_id": "SEPT2_DROME", "id": "P54359-1", "name": "Septin-2", "aln": "--------MSVEVDFVD--KKEVHLRTLKQSGHVGFDSLPDQLVN--------------KSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFES---------TPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDET----VAETNTSMNSHIPFAVVGSTEFIKVGNKLIR--ARQYPWGTVQ-VENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQ--MGFSDVDSDNKPIS--------------FQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAE-------------------------EKRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSKKK-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32458-1", "uniprot_id": "CDC11_YEAST", "id": "P32458-1", "name": "Cell division control protein 11", "aln": "-MSGIIDASSALRKRKHLKRGITFTVMIVGQSGSGRSTFIN----------------------------TLCGQQVVDTSTTILLP-----------------TDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRR-NPRFKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEMGGDVGTIRGRKYPWGILD-VEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEALSGESVAAESIRPNLTKLN---------------GSSSSSTTTRRNTNPFKQSNNINNDVLNPASDMHGQSTGENNETYMTREEQIRLEE--------------------------ERLKAFEERVQQELLLKRQELLQREKELREIEARLEKEAKIKQEE---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07657-1", "uniprot_id": "SHS1_YEAST", "id": "Q07657-1", "name": "Seventh homolog of septin 1", "aln": "MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKR-NPRFEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEGRYV-----REYPWGIIS-IDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSS-VANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * : :. :. .:. . :. : . : :.: * * *:.::.. . : : .*: *:: * ** :::* .* *:* .**:* ****.*:.:*: ::.:. .*::*:*:::*:::: :* : *: :: .: **:: * : : * ***:: * . * : *.**** :. :::.. .*: *:: *: :::.:::: *: ** ** . *. . .: . . .: . ::: . : : . ::: . . . * * : . . ", "identical_positions": 53, "similar_positions": 124, "identity": "9.45%" }, { "cls_id": "homologset.agr.HGNC:33282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEEGDRGDS--VDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQEGDRRES--VNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC4-1", "uniprot_id": "CT47A_HUMAN", "id": "Q5JQC4-1", "name": "Cancer/testis antigen 47A", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEE--EEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMA----REPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQ---PEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : * . ..****:* .. ***:: .: . .. : .* *:::* :*::*::**:**::*:*: :***** .: : . * .::: . : * . *: :* .* : ::.** ** : * :*.: ** : :.* * *: * *:* .::.: ..::.:: *:: *:: :::. :::. . ", "identical_positions": 60, "similar_positions": 104, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:33293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3U9-1", "uniprot_id": "A2A3U9_MOUSE", "id": "A2A3U9-1", "name": "", "aln": "MSTTSDQDPAIESRDNPLTLEGEWVQEALESGAVDLDG--SSATTESEEIVVDCPREVEDVG-AGSPEEE--GDRGDSVDVEEDSEIEAVTEEEEEGEEEEGVLGRQNVVVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILARDPRNE--MDTPNTSESDNSSERQTSPEPIPSTVRASEYEHQGPDLPEVISTFPELEEPAAFEEAADHYLQETTAGAAGQAIEEMAAAAAEEVAEASEEEIAKEIIEQAVASEGENRCARQYEEDETIDEGEKKGEEKKNEEALDEMDPDAANYYTNKFS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8J5-1", "uniprot_id": "A0A0G2K8J5_RAT", "id": "A0A0G2K8J5-1", "name": "", "aln": "MSTRGRRDPTRESRDNPVTLEGEWVLEAAEGGAVGLDG--SSATLEAEEVVVDCHREVEDVGPERNPEQE--GDRRESVNVEEDSDIEAVEEEEDD-QHQESDLANQN-VVDAHHFPMAGFRFMFLDLVHAILNRVYYNDHILVRDPRENQVMGSSNTSESGHPRELQVPPGPIPSTVRASEYEHQGSDLPEVISTFPELEEPADFEED---YLQEPAFRAAGQAVEEVA-------EEAAAEEPAKEIIGQAMTSEGENHCARQYKDDNIVDEEEEEEEEEMKNEGFEKMDSDAEDYCTNKFS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C2W7-1", "uniprot_id": "CT47B_HUMAN", "id": "P0C2W7-1", "name": "Cancer/testis antigen family 47 member B1", "aln": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDMVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPQGGSAEEDSDIGPATEEEEE-EEEGNEAANFDLAVATRRYPAAGIGFVFLYLVHSLLRRLYHNDHIQIANRHLSRLMVGPHAAVPNLWD--NPPLLLLSQRLGAGAAAPEGEGLGLIQEAASVQEAASVPEPAVPADLAEMAREPAEEAADEKPP------EEAAEEKLTEEATEEPAAEEPTSEEAVAP-EEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDVENKVKNSKGT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . :.*: .:: *:: ** . * .. . *. .*: . **. **.:* . : . :. ..****:* .. ***:: :.: . .. : .* ::::* **: *:** ***::*.*:*:**** : : . * .::: .. : . :.. : *. :* .* : .: . * .: * * * : .* :* :* . **: *: ::* :. :.* .. * :: .: *: ** . . :: : : . **.. ", "identical_positions": 61, "similar_positions": 105, "identity": "19.74%" }, { "cls_id": "homologset.agr.HGNC:333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFC2-1", "uniprot_id": "SP88E_DROME", "id": "Q9VFC2-1", "name": "Serine protease inhibitor 88Ea", "aln": "-------------------------------------------------MHILSISLMAVLPAIALAGLCGVEPDAGLLDQRLNLYKGQQNFAVSMLNVIRQST--------------PNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEVV-RSAYILEKMNRKER---------QSKMPLEFSSADRIFFANDLHVTECARNRLAEEVQQIDFKS---QTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSET---IS--IGDSKHVAKIKVDEEGSTAAAATVLFTYRSA------RPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDPKTIKQ-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFC1-1", "uniprot_id": "Q9VFC1_DROME", "id": "Q9VFC1-1", "name": "", "aln": "-------------------------------------------------MHTFSLVLLALLPVVTIAALD--KPELSFLNEFSQIFKGERDFSLALMKQIREIY--------------PSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQV-LVSYTLAQRQDEFR---------WRQSPMELSSANRIFVDRTINVSNKFNTLLYGATKELDFKN---DPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRN-ATFGDLTADP---ISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSS------RQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDPRQMQH-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VII7-1", "uniprot_id": "Q9VII7_DROME", "id": "Q9VII7-1", "name": "", "aln": "---------------------------------------------------------------------------MKYLCLLLLATSVSCRFTDDLYQLLAKEN--------------ADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLP-DDKKE----VAAKFKDLLSKLE---------GRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITASIVNKWVDTQTSGKIRDLVMPSDV-ANLVLVILNAIYFKGQWQKKFNTEQTKS-DFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYR---------------NSNLSMVIFLPDKV-----DGLPELEKKMVGFTPK-LININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTS-ADFNDLVAN----SGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKS----IRSPP--MDFNVNHPFAYVIRDA--ENIYFQGHFVNPEL----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLQ7-1", "uniprot_id": "Q9VLQ7_DROME", "id": "Q9VLQ7-1", "name": "", "aln": "---------------------------------------------------------------------------MKHLCLLLLATSVSCRFADDFYQLLAKEN--------------AANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLP-DDKKE----VAAKYKDLLSKLE---------GREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNNWVDNQTRGKIKDLVSSNDM-SKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHDSELGAKIIELPYR---------------NSSLSMLIFLPDQV-----DGLSELEKKIVGFKPK-LSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKS-ADFKDLVEN----SNVHVKKVIHKAFIEVNEEGAEAAAATALLFVRYS----MPMPSSQMVFNADHPFAYVIRDR--ETIYFQGHFVKPNE----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLZ8-1", "uniprot_id": "Q9VLZ8_DROME", "id": "Q9VLZ8-1", "name": "", "aln": "---------------------------------------------------------------------------MKYLYLLLLATSVESGFWEDFYRILASQN--------------AKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFS-ENKTL----VANNYRSLLSDLK---------RRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYIDDIDAKIIELPYW---------------NSTLSMRIILPNSV-----DGLRKLKEKVGFIDYH-LEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPS-ADLNGLVLE----SGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPP--MEFIADHPFFYVIHDN--KVIYFQGHIVEPRW----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7YTY6-1", "uniprot_id": "SP42D_DROME", "id": "Q7YTY6-1", "name": "Serine protease inhibitor 42Dd", "aln": "---------------------------------------------------------------------------MYYLCIFLWVTSVACQTSKEIYQLLSKSH--------------TNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEA----VAARYGALLNDLQ---------GQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYL---------------NSNLSMTIFLPREV-----EGLSALEEKIVGFARP-LVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDK-SDLSGLFADK---SGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAG-----FST---FLMADHPFAFVIRDA--NTIYFQGRVVSP------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8V6-1", "uniprot_id": "Q0E8V6_DROME", "id": "Q0E8V6-1", "name": "", "aln": "---------------------------------------------------------------------------MKYLCWILVTTSVLGQFTKQLYRSFLQDN--------------KQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLP-EDKKN----VATIYDKLLTKLE---------RGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGRFKMR--TSTIDQIIELPFA---------------YSNLSMVIVLPKDN-----GSLTQAEATIESYPQIVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSS-SDIS-VLLNQ---SGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYA---TSV--VTFTVNSPFVFMIRDD--DNIYFRGRVVDPLKKSNPIDRITI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLV3-1", "uniprot_id": "Q9VLV3_DROME", "id": "Q9VLV3-1", "name": "", "aln": "---------------------------------------------------------------------MQGNNKIKYLVLLLIATSVLGKFKLNLL-ELVMDK--------------AESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLP-VDVTE----MAKKYERIMSNFQ---------KHN---GLRFTNWLYVNETYEVRQDYNTLMKSTFMAEGKDP-LSQR-KASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMSHVGRFRIA--DHSYGQIIEMPFD---------------NSDLSMIIGLPLHN-----TYLSSIEKILRTLSES-LVENNVHVELPKFKIKYQTELVESLKKLGIHLIFSNT-SDLSGLLTNG---TGAKINHVVHKSFIEINERGASTGEASDHAES-IQKKT---RAS--TSFKVNRPFVFLIRDK--HTVYFRGRVVRLPNELHL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P01015-1", "uniprot_id": "ANGT_RAT", "id": "P01015-1", "name": "Angiotensinogen", "aln": "MTPTGAGLKATIFCILTWVSLTAGDRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGA-VLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRG--FSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLG----------------ESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKN-PPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAE-ANLGKMGDT-----NPRVGEVLNSILLELQAGEEEQPTESAQQPGSPE----------VLDVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11859-1", "uniprot_id": "ANGT_MOUSE", "id": "P11859-1", "name": "Angiotensinogen", "aln": "MTPTGAGLKATIFCILTWVSLTAGDRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGA-ILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRG--FSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLG----------------ERATLLLIQPHCTSDLDRVEALIFRNDLLTWIEN-PPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE-ANLSNIGDT-----NPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPE----------ALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01019-1", "uniprot_id": "ANGT_HUMAN", "id": "P01019-1", "name": "Angiotensinogen", "aln": "MAPAGVSLRATILCLLAWAGLAAGDRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLDF-TELDVAAEKIDRFMQAVTGWKTGCSLMGASVDSTLAFNTYVHFQGKMKG--FSLLAEPQEFWVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVPFT----------------ESACLLLIQPHYASDLDKVEGLTFQQNSLNWMKK-LSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTE-LNLQKLSND-----RIRVGEVLNSIFFELEADERE-PTESTQQLNKPE----------VLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3N1-1", "uniprot_id": "SP27A_DROME", "id": "Q9V3N1-1", "name": "Serine protease inhibitor 27A", "aln": "----------------MTKMGGNLAVMLLSLFLSALATGNGNSIPTTTTPQGVFETRTDKLPGGAASVPSGAGIYDDIDTFVPFRSDSHDPFSWHLLKTVLQNET-------------ADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANTQTDIRSQNN---VREFYRKTLNSFK--------KENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNPEAAADAINAWAANITQGRLQQLVAPDNVRSSVMLLTN-LIYFNGLWRRQFATTFQGS--FFRSKDDQSRAEFMEQTDYFYYTTSEKLKAQILRLPYK----------------GKNSLFVLLPYALNG-IHDLVKNLENDELKSAQWAMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIFEDS-ASLPGLTRGADVAGKVKVSNILQKAGINVNEKGTEAYAATVVEIENKFG-----GSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSPTTQN--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL44-1", "uniprot_id": "Q9VL44_DROME", "id": "Q9VL44-1", "name": "", "aln": "------------------------------------------------------------------------------MSEAANPTPYDCHIGAGIYHSIATSF--------------AEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAK--MANFYAAELGNIT----------TDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLLAANLQSKWFLPFSAYRTGLYEFHSGSQVKSVPMLFDDDMFVKFAELRDLDARAIELPYEH--------------AEELSMLLILPNQRGG-LQELEKQLHDLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAAS-ANFKHLHAS----ANLPIADVLQKLRINLNESGSGSGPELPKNATEYKPIVIS-NSSRQKFFRADHPFFFAIRSE--NVTYLMGHVVEF------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ** : .: * .: . : . .. * :: . :* : : * . : : :*:: : * : . : : : : : :::. . . ** : : . : * ", "identical_positions": 11, "similar_positions": 42, "identity": "2.11%" }, { "cls_id": "homologset.agr.HGNC:3330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8C3-1", "uniprot_id": "EMAL1_RAT", "id": "Q4V8C3-1", "name": "Echinoderm microtubule-associated protein-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEISDRIASLEQRVQMQED----------------DIQLLKSALADVVRRLNITEEQQAVLNRKGP-------------TKARPLGQTLPLRTTVNNGTVLPKKPSASLPSPSGSRKEMVVPVTKS-INRTSSSERVSPG----------------------------------------------------------GRRESSGDSKGSRNRTGSTSSSSSGKKNSESKP---KEPTFSPEEGYVKMFLR-------GRPVTMYMPKDQVDS-------------------------------YSLEAKAELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGSHLCAVDDSNDHVLSVWDWQREERLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGNSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTN--RISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRRLISWN--GNYQKLHKAEIPEQFGPIRTVAEGK----GNVILIGTTRNFVLQGTLTGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPE---GSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05BC3-1", "uniprot_id": "EMAL1_MOUSE", "id": "Q05BC3-1", "name": "Echinoderm microtubule-associated protein-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVSDRIASLEQRVQMQED----------------DIQLLKSALADVVRRLNITEEQQAVLNRKGP-------------TKARPLGQTLPLRTTVNNGTVLPKKPSASLPAPSGARKEVVVPVTKS-INRTSSSERVSPG----------------------------------------------------------GRRESSGDSKGSRNRTGSTSSSSSGKKNSESKP---KEPAFSPEEGYVKMFLR-------GRPVTMYMPKDQVDS-------------------------------YSLEAKAELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGGHLCAVDDSNDHVLSVWDWQKEERLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGNSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTN--RISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRRLISWN--GNYQKLHKAEIPEQFGPIRTVAEGK----GNVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPE---GSDGTDINAVCRAHERKLLCTGDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00423-1", "uniprot_id": "EMAL1_HUMAN", "id": "O00423-1", "name": "Echinoderm microtubule-associated protein-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQED----------------DIQLLKSALADVVRRLNITEEQQAVLNRKGP-------------TKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKETAVPATKSNIKRTSSSERVSPG----------------------------------------------------------GRRESNGDSRGNRNRTGSTSSSSSGKKNSESKP---KEPVFSAEEGYVKMFLR-------GRPVTMYMPKDQVDS-------------------------------YSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTN--RISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWS--GNYQKLRKTEIPEQFGPIRTVAEGK----GDVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPE---GSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXY5-1", "uniprot_id": "E7EXY5_DANRE", "id": "E7EXY5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEDGFSSYSSLYDTSSLLQFCNDDSASATSSMEVTDRIASLEQRVQMQED----------------EIQLLKSALADVVRRLNISEEQQAMLNKKGP-------------TKARPMIAALPLRPTVNNGTVLPKK-GGTLPSPSNCKKDNNSPATRSTVKRTSSSEHVGPN----------------------------------------------------------NRKDSGVDSKNNRTRAGSTGSNSSGKKTTETKQ---REPVFSADEGYVKMYLK-------GRPITMYMPKDLVDT-------------------------------YCLETKADLPPKKLKLDWVYGYRGRDCRSNLYLLPTGETVYFIASVVVLYNVDEQLQRHYTGHTDDIKCLAVHPDKITIATGQVAGTSSDGKQLAPHVRVWDSVSLNTLHILGNGFFDRALVCLSFSKSNGGSWLCVVDDSNDHMLSVWDWQREDRLAEVKCSNESVFAADFHPTDANIIVTCGKSHLCFWSLEKGSLVKKQGLFEKQEKPKFVLCVTFSENGDAITGDSSGNILVWGKGSN--RISLAIQGAHEASVFALCMLRNGTLVSGG-KDRKLISWD--ENFQKIQTVEVPELYGPVRTVAEGR----GETVLIGTTKNYVLQGSLNGEFIPITQGHTDELWGLTIHPLKHQFLTCGHDKHIYLWDSDSHQPIWTKTLEDSAQSAGFHPSGATVAVGMQTGRWLVLDTESKDLVTVHTDGNEQLSVIRFSPDGNFLAIGSHDNYIYIYAVAENGKKYSRVGKCSGHSSFITHLDWSVDSQYLVSNSGDYEILYWIPSVCKQVVSVETTRDIEWATFTCTLGFHVFGLWPD---GSDGTDINAVCSSYAKRLLVTGDDFGKVHLFSFPCSQSRAPSHIYSGHSSHVTNVNFLFDDSHLVSTGGKDMSIMQWRVV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUI3-1", "uniprot_id": "EMAL_DROME", "id": "Q9VUI3-1", "name": "Echinoderm microtubule-associated protein-like CG42247", "aln": "MPQISPNAPLEGNVSPPPTQPHLDDNLHNGNGNGNGIHSSSSNINKHGSNINGNNDSNRSSPAKSPKRPVSSSFRIQNTSRYDNDEEDLAASEQVAGGDRQVPDYWQQRNGATTGATSGRQSRAISPGYLDNMSENSEQPPVVPLVRSKSRPEISSAAASRYNNLSYWKARRVVFYRNGDPFFPGVELRYRPGRDVTSLDNLLDKISPKMDLPRGARYVFSMDGDRKYHLDELEDGAFYVVSSFKAFKPASYGKKNGMWYASPGNQGWGSKPASRKPSIMEADLGTLSTTSGSIKRSAGRVIRIINNLDHSVQCRVLLNLRTSQPFEEVLEDLGQVLKINGAKKMYTGTGQEVRSFSQLRNEFADVDTFYLATGTALIAGSPIRRSRSRPSVVAAAPILPTDELPKVPLRGARPRSKSRPRILYAPESEILRPNGEYTMLDIMKEEPTKVTIRGLRRTFYPPVHHAPADNSPPDKKLQLQWVHGYRGIDARRNLWVLPSGELLYYVAAVAVLFDRDEDAQRHYTGHTEDIMCMDVHPSRELVASGQKAGRDRKSQ---AHVRIWSTESLQTLYVFGMGELDSGVTAVAFSQLNGGSYILAVDSGRESILSVWQWQWGHLLGKVATLQEGLSGAAFHPLDDNLIITHGRGHLAFWHRRKDGFFERTDIVKQPSRS-HVTSVQFEPDGDVITADSDGFITIYSVDSDGAYFVRTEFEAHNKGIGCLIMLGEGTLLSGGEKDRKIAAWDSLQNYKKIADTKLPEAAGGVRTIYPQRPGRNDGNIYVGTTRNNILEGSLQRRFTQVVFGHGRQLWGLAAHPDDELYATAGHDKHVALWRK--NKLIWTIQTGYECVALAFHPFG-TLAAGSTEGHLLVINCENGAVMLTLRVCGSPLNCVAYNQVGDMIAMGSQNGSIYLFRVSRDGFSYKKVNKIRG-SQPLTHLDWSMDGNFVQTVTIDFDLLFWDAKSLSPERSPIAMKDVKWLTNNCTVGFLVAGQWSNRYYSTTNTIVATCSRSAAHDMLASGDAEGYLRLFRYPCISPRAEFHESKVYSGMLACVRFLCGDHTLITVGGTDASLMVWDIVEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:*. *. . .*:: . . *:::: . .: :** : .: :: *.. * .: ::::.. : ::. .* . .: * :** .. : . :* . . :. **.* : ... ::. * :*:: .* : :.:: . : . : *: *: .** :* *:. : : :. . * *:*:*:**:**** *.* **::**:** :*::*:*.**:: :*: ****:**.:*: *: ***.: :*:** ** . ..: .***:*.: :*:**:::* * :* .:..::**: *** : .**...: :****:** . *..* :*.: .* *** * *:*:* *:.** ** . ..: :: .:.:: .:. .* .* *. :**.**.**.* * ::. .:: : : **: .: .* ** :***:*** ***:: :*. *::*: .::** * :**: : . : :***:* :*:*:* * :. ** :****: *. . : *.***** ** :: :* . : .*** * .:*.* *: :*:: *. :: . .. *. : :. *:::*:**::. **:: *: :* .*.:*.* * *. :******::.::: : : *:::*:* .. . * : :*::* * .**:** * * *.: .: .* : : . : : :* :** * ::** :** . ** * :*. :: * ** * *::.**.* *:* * :: ", "identical_positions": 229, "similar_positions": 300, "identity": "21.13%" }, { "cls_id": "homologset.agr.HGNC:3331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63190-1", "uniprot_id": "EMD_RAT", "id": "Q63190-1", "name": "Emerin", "aln": "MDDYAVLSDTELAAVLRQYNIPHGPILGSTRKLYEKKIFEYETQRRRLSPPSSSSSSFSYRFSDLDSASVDSDMYDLPKKEDALLYQSKDYNDDYYEESYLTTRTYGEPESVGMSKSFRRPGTSLVDADDTFHHQVR-DDIFSSSEEEGKDRERPIYGRDSAYQSIAEYRPISNVSRSSLGLSYYPRSSTSSVSSSSSSPSSWLTRRAIRPEKQAPTAALGQDRQVPLWGQLLLFLAFATFLLFVYYSIQAQEGNPFWMDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08579-1", "uniprot_id": "EMD_MOUSE", "id": "O08579-1", "name": "Emerin", "aln": "MDDYAVLSDTELAAVLRQYNIPHGPIVGSTRKLYEKKIFEYETQRRRLLPPNSSSSSFSYQFSDLDSAAVDSDMYDLPKKEDALLYQSKDYNDDYYEESYLTTKTYGEPESVGMSKSFRQPGTSLVDAD-TFHHQVR-DDIFSSLEEEGKDRERLIYGQDSAYQSIAHYRPISNVSRSSLGLSYYPTSSTSSVSSSSSSPSSWLTRRAIRPEKQAPAAALGQDRQVPLWGQLLLFLVFAAFLLFVYYSIQAEEGNPFWMDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50402-1", "uniprot_id": "EMD_HUMAN", "id": "P50402-1", "name": "Emerin", "aln": "MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAAS-SYSFSDLNSTRGDADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDAD-AFHHQVHDDDLLSSSEEECKDRERPMYGRDSAYQSITHYRPVS-ASRSSLDLSYYPTSSSTSFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLFFIYHFMQAEEGNPF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QIK0-1", "uniprot_id": "E9QIK0_DANRE", "id": "E9QIK0-1", "name": "", "aln": "MSSLSVKSDKEICQLLDEYGIKHGPIVESTRKLYEKKLNEAMAKKTKPSSPD------------------------------------KTYYREEQEE--VEYVTYHQPQQQTRHEVYGDVTRRSKASDSDFAHDVG--------------SKLSAYREDVDYT----NEPVTRQSHSAYQSSSRPPSSKPVQSAESTKS-----------------------AGVPAWLRILVFLIIAAFLYYVYTSMEPAEETPFKTIQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. : **.*: :* .*.* ***:: ***:*****: * ::: : .*. * * : ** . ** :*:. . :* * *:* : * .* * .*:: *:*: * * **.. :.*:.. ** * ::*:** :. .* ::* ::. * .** ", "identical_positions": 53, "similar_positions": 52, "identity": "20.31%" }, { "cls_id": "homologset.agr.HGNC:3332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7KZI7-1", "uniprot_id": "MARK2_HUMAN", "id": "Q7KZI7-1", "name": "Serine/threonine-protein kinase MARK2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQ-------------------------PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ-IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRT------------ELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEG------DTITLKPRPS----ADLTNSSAPSPSHK-VQRSVSANPK-QRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAAR---PRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS---GHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPESKDR-----VETLRPHVVGSGG--NDKEKEE-------------------FREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05512-1", "uniprot_id": "MARK2_MOUSE", "id": "Q05512-1", "name": "Serine/threonine-protein kinase MARK2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQ-------------------------PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKIDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ-IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRT------------ELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEG------DTITLKPRPS----ADLTNSSAPSPSHK-VQRSVSANPK-QRRSSDQAV-PAIPTSNSYSKKTQSNNAENKRPEE--ETGRKASSTAKVPASPLPGLDRKKTTPAPSTNSVLSTSTNRSRNSPLLDRASLGQASIQNGKDSLTMPGSRASTASASAAVSAAR---PRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSSGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS---GHSQGRRGASGSIFSKFTSKFVRR---------NLNEPESKDR-----VETLRPHVVGSGG--TDKDKEE-------------------FREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHERYMLLCVHGTPGHENFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08679-1", "uniprot_id": "MARK2_RAT", "id": "O08679-1", "name": "Serine/threonine-protein kinase MARK2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQ-------------------------PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ-IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRT------------ELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEG------DTITLKPRPS----ADLTNSSAPSPSHK-VQRSVSANPK-QRRSSDQAV-PAIPTSNSYSKKTQSNNAENKRPEE--ETGRKASSTAKVPASPLPGLDRKKTTPTPSTNSVLSTSTNRSRNSPLLDRASLGQASIQNGKD---------------------------------------------------------STAPQRVPVASPSAHNISSSSGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPFGVTPASPS---GHSQGRRGASGSIFSKFTSKFVRR---------NLNEPESKDR-----VETLRPHVVGGGG--TDKEKEE-------------------FREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHERYMLLCVHGTPGHENFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B4V1-1", "uniprot_id": "A0A8M3B4V1_DANRE", "id": "A0A8M3B4V1-1", "name": "MAP/microtubule affinity-regulating kinase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTRIPLLAIHDHSSGQ---SHSDSKPGGRSTMPHS-----TADEQ-------------------------PHIGCYRLLKTIGKGNFAKVKLAKHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKLLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTLGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPTKRGSLEQQIMKDRWMNVGHEDEELKPYIEPQPDYKDPKRTGQHPSSAGGWKRDIMIRMGYSLDEIQDSLINQKYNDVMATYLLLDYRNSELDE--------LSIKARPG----TDITN-NAQSPSHK-GQRSTSNLKS--RRSTDQSS--------VSSKRPQGDSKH-IGSSG---------SSSKVPPSPLISGDHKKT-PTPSTNSILSSGTGRSRNSPITERATLG---VQNGKDSLHTPGSRASTASAAAVLAASS---RTRHHKSLSTSAHPSPP--------DLHAHRPSTANQRAPVVSPSAQNINISSMA-DRTNFSRGVTSRSTFHAGQQRATRDQQASAYNDPSASPSLSHGNSQVRRPGT-GIFSKFTSKFVRRNLSFRFPRRSPYEGEGRDEASRPMLSTADKMEKGTQGHPSDENKDSFSSSSPASSTPSSTQAS---KDTKPRSLRFTWSMKTTSSMEPNEMMKEIRKVLDSNSCEYELRERFMLLCMSGNPAHDDFVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BAY8-1", "uniprot_id": "A0A8M3BAY8_DANRE", "id": "A0A8M3BAY8-1", "name": "MAP/microtubule affinity-regulating kinase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTRPQGVAVIENSSSQ---THSDAKGGVRSSAPRCRNAVATAEEY-------------------------PHIGNYRLLKTIGKGNFAKVKLARHVLTSKEVAVKIIDKTQLNSSSLQKVFREVRIMKLLNHPNIVKLFEVIETDKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPTKRGSLEQQIMKDRWMNVGYEDDDLKPYIEPQPDYKDPRRT------------DIMLQMGFSQEEIEDSLVKQKYNEVMATYLLLDYRNSELDEG-----VNLSLKSRPG----SDLTNSNAPSPPHK-VQRSVSSTQKPARRSTDQGS--------YS-KRPQGENKHGVEDSGR----KGSSSSTKVPPSPVISSERKKS-STPSTNSILSTGTSRSRNSPISERATLG---VQNGKDSLSTPGSRASTASAGPVLSSSSSSSRTRHHKSLSTSAHPSPA--------DLHSHRPSDPPQRAPGASPSAHNISSAAGT-DRTNFPRGVPTRNTFHLGQQRGARDQQGSPYHGAPASPSLSHGNSQQRRPAASGIFSKFTSKFVRRNLSFRFPRRSPYEGEGQEEGSRSMLSSAEKSEKTSVG-PEDENKD--PSSSPGGGTPPAAPVSSLKDQSKPRSLRFTWSMKTTSSMEPSEMMKEIRKVLDANSCEYELRERYMLLCMAGNPARDDFVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBL9-1", "uniprot_id": "A1ZBL9_DROME", "id": "A1ZBL9-1", "name": "MAP/microtubule affinity-regulating kinase 3", "aln": "MSTAMRTTLQSVPEALPADSVSNGTASNVAAPAAPVSSATNAVPPLAAVSSTTATYATNSISTSSHSVKDQQQQQQQQQHDSANANIVSLPPTTTPVANTNTMMPIVTSSNSATSNSTAATPTPASGAAATGGVGSVSQGPATVSASAANTNHSHQHSHQHHHHVANNMTTDGARLSSNNSAVVASSAINHHHHHTPGSGVAPTVNKNVLSTHSAHPSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLET-IMGDKWMNMGFEEDELKPYIEPKADLADPKRI------------EALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDGSRSGSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISASST---KPSRRAS---------SGVGPTNAAATVAAATG----AVGAVNPSNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQRPASATQKMLTTADTTLNSPAKPRTATKYDPTN----GNRTVSGTSGIIPRRS------TTLYEKTSSTEKTNVIPAETNLFDRLRMASAVKSSRHFPRNVPSRSTFHSGQTR-ARNNTALEYSGTSGASG------DSSHPGRMSFFSKLSSRFSKR-------------PTIAD------------------------------------------------EAAKPRVLRFTWSMKTTSPLMPDQIMQKIREVLDQNNCDYEQRERFVLWCVHGDPNTDSLVQWEIEVCKLPRLSLNGVRFKRISGTSIGFKNIASRIAFDLKLXLNQTNNEGNAAATASRPTDPTDTMTTTNCRRPSNDSTSRLSELSLLCRSLTSQQGSQRRKKSRLSTGGSEDQKKSNSLLSAFQMYSPFSSKENMQSSEEVEDLHVIDTQPGHSVDVPLFADFSPINPIMEEDAEGVEGGKTSEAKVISGGSGQKVKGDGGGGGGGNRLKRNIKHTGSLIVRKLTAGRHNDADKKGAIRKKDKEQQEVADTDKERPTSKPEGKVAMLRTTTL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . : . ... :* : *** *:*:**************:*: *.****:*********..****:********:*:********:****:*****:************** **********.*************** *:************:::************** *.********************* **************************..*:*************************:***:***:**.:** ** *:***:*.*:::****:** .* **:* : :: **:. .**: ** :*::*:******. :.:: : :::: .. :: . .. **.*: :** * . : : :. . . ..:: :. . :: . . . :. :.:.* :...: : : *: : : * : ..: :. . . :*.*.*.:*.*** ** * .*:: : ...:.. : : . .:***::*:* :* : :*** ***********.: *.::*::**:*** *.*: * :*:::* *: * * :.:****:**********************:.******:** :*** ", "identical_positions": 340, "similar_positions": 171, "identity": "26.62%" }, { "cls_id": "homologset.agr.HGNC:3333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54848-1", "uniprot_id": "EMP1_RAT", "id": "P54848-1", "name": "Epithelial membrane protein 1", "aln": "----------------------MLVLLAGLFVVHIATAIMLFVSTIANVWMVADGIDSSIGLWKNCTSGSCDGSLSYG------NDDAIKAVQAFMILSIIFSIISLVVFVFQLFTMEKGNRFFLSGSTMLVCWLCILIGVSIYTHHYAHSEGNFFPSSHQGYCFILTWICFCFSFIIGILYMVLRKK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47801-1", "uniprot_id": "EMP1_MOUSE", "id": "P47801-1", "name": "Epithelial membrane protein 1", "aln": "----------------------MLVLLAGLFVVHIATAIMLFVSTIANVWMVADYANASVGLWKNCTGGNCDGSLSYG------NEDAIKAVQAFMILSIIFSIISLVVFVFQLFTMEKGNRFFLSGSTMLVCWLCILVGVSIYTHHYAHSEGNFNSSSHQGYCFILTWICFCFSFIIGILYMVLRKK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54849-1", "uniprot_id": "EMP1_HUMAN", "id": "P54849-1", "name": "Epithelial membrane protein 1", "aln": "----------------------MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYA------SEDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANRDG---TQYHHGYSYILGWICFCFSFIIGVLYLVLRKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJK5-1", "uniprot_id": "A0A8M3AJK5_DANRE", "id": "A0A8M3AJK5-1", "name": "Epithelial membrane protein 1", "aln": "MAAFSISIKDIVASCFPSRPLNMLKALAGICLLHLTTIFFLFWATIDDAWWFTRTLYT--DLWGQWVMENNDNVWVYMDIPTSYRKDYLQAVQGFAVLSCLFAVFSLIVFIIQLFTLGKGKRFILSGVVQLISCFCIMVALSVYTDHFHRGEK----DGWYGWSYIMAWFGWLLTLFTGIMYIILRKRVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***: ::*::* ::** :** :.* .: : .** : . . .. * .* :::**.* :** :*.:::*:**::****: **:**:*** . *:. :**::.:*:** *: . : . *:.:*: *: : :::: *::*::***: ", "identical_positions": 51, "similar_positions": 64, "identity": "26.84%" }, { "cls_id": "homologset.agr.HGNC:3334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HH2-1", "uniprot_id": "EMP2_RAT", "id": "Q66HH2-1", "name": "Epithelial membrane protein 2", "aln": "MLVILAFIIVFHIVSTALLFISTIDNAWWVGDGFSADIWRVCTNSTNCTEINDLSSTEEFSGYSVMQAVQATMILSTILSCISFLIFLLQLFRLKQGERFVLTAIIQLMSCLCVMIGASVYTDRRQDLHHQNSQLYYLLQEGSYGYSFILAWVAFAFTFISGLMYMILRKRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88662-1", "uniprot_id": "EMP2_MOUSE", "id": "O88662-1", "name": "Epithelial membrane protein 2", "aln": "MLVILAFIIVFHIVSTALLFISTIDNAWWVGDSFSADLWRVCTNSTNCTEINELTGPEAFEGYSVMQAVQATMILSTILSCISFLIFLLQLFRLKQGERFVLTSIIQLMSCLCVMIGASIYTDRRQDLHQQNRKLYYLLQEGSYGYSFILAWVAFAFTFISGLMYMILRKRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54851-1", "uniprot_id": "EMP2_HUMAN", "id": "P54851-1", "name": "Epithelial membrane protein 2", "aln": "MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDS-----FQEYSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QIK8-1", "uniprot_id": "EMP2_DANRE", "id": "F1QIK8-1", "name": "Epithelial membrane protein 2", "aln": "MLVILAFIILFHITSAILLFIATINNAWRIKGDFSMDLWYNCN-TTACYDIPKS----ATYDAAYLQAVQATMILATILCCVGFFVFILQLFRLKQGERFVFTAIIQLLSAFCVMTGASIYTAEGLTFNGQE------FKNAEYGYSFVVAWVAFPMTLLSGLMYLVLRKRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***** ***.*: ****:*::*** : . * *:* *. .* * * . : :*********:***.*:.*::*:*************:*:****:*.:*** .**:** . :: :: ::..****:::*****. *::**:**::*****", "identical_positions": 87, "similar_positions": 46, "identity": "50.58%" }, { "cls_id": "homologset.agr.HGNC:33340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VE94-1", "uniprot_id": "F110C_MOUSE", "id": "Q8VE94-1", "name": "Protein FAM110C", "aln": "-MRALPTLDSLARMRPPLGDP----RAAEDTLTPRPANKSAVERLAADRAKYVRSTLGSSRGPVSEHRVPEAPGVQH---------RNPIPSALAPAPVARRAIARKP--LRPDSLVIYRQKCEFVRGSDADCSRVGLMKKFFQGSGKDKMAVAPETTRVADEDKTTKETEATWTKSSQAAAARPASMLPPPTPVVAVKSPAEKTRVANEDKTTKETEATWTKSSQAAAARPASMLPPPTPVVAVKSPAEKTRVANEDKTTKETEATWTKSSQAAATRPASMLPPPTPVVAVKSPALPFEVAPRVPVGCSGVQLRVSRSKGLQRSQSDLSSRYSIAKAESDTFFKYCGLDPDVVEALGRENFSAGSDCVTLKVRSVSMAASDSSFSRHS---EDGLQEEELLEQVPSTTSVVERNARIIKWLFTCKKAKETPSQKLQGPA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RKJ0-1", "uniprot_id": "F110C_RAT", "id": "Q5RKJ0-1", "name": "Protein FAM110C", "aln": "-MRALPTLDSLARTRPSLGDS----RAAEGTLTRQPANKSAVERLAADRAKYVRSTLGSSRGPVSENRVPEAPGVQH---------RNPIPSTLAPAPVARRAVARKP--LRPDSLVIYRQKCEFVRGSDADSSRVGLMKKFFQGSGKDKMSVTPETTRVADEYKT-----------------------------------------------------------------------------------------------KETEATWTKASQAAAAKPASMLPPPAPVVAMESPALPFEVAPRVPVRRSGVELRASRSKGLQRSQSDLSSRYSTARAESDTFFQYCGLDPEVVESLGRENFSAASDCVTPKMRSVSMATSDSSFSRHS---EDGLQEEELLEQVPSTTSVVERNARIIKWLFTCKKAKETPSQKLQEPA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1W6H9-1", "uniprot_id": "F110C_HUMAN", "id": "Q1W6H9-1", "name": "Protein FAM110C", "aln": "-MRALAALSAPPNERLLPRDP----AATRDPDAARPARRSAVERLAADRAKYVRGRPGTGRGVASEGSGPGAIKCPG---------NDPGPPARAPAPVARRAIARKP--LRPDSLIIYRQKCEFVRGSGADGPRASLVKKLFQGPGKDKAPVP----RTGDEGKAG-----------------------------------------------------------------------------------------------NPETVPTTPG--PAADPA---IPETPAPAARSAAP-----SSVPAAPPGPEPRVVRRRGLQRSQSDLSSRYSAALAESDTFFQYCGLDPEVVEALGRENFTAGSDCVTLKVRSVSVATSGSGFSRHSGGDDEGLQEEELIEQVPSTTSVIERNARIIKWLYTCKKAKETPSQEQSRTRGSKPSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E4Y7-1", "uniprot_id": "A0AB40E4Y7_DANRE", "id": "A0AB40E4Y7-1", "name": "", "aln": "MLKKTQGSFEVDPSRILVKGPEFLRKQMERENEANKGRVSAVERLAATKPQYVKCQQEVGSSQEPVISTGSASGSSRGSSKGDGSVKNTVNVDYKELPEEDSNVVRRSSSKKRDSILLYRQKCELLRG--APVLRRRLNRKPLLTVRDKGGESDRATSKECGKESS--------------------------------------------------------------------------------------------------QVTLTASGTNEVQRAT----PHRKVLETK-------------------EQERKSRTGVARSSSDISSRYSKNFADFDVFFKYCGLDGDIIESLGKENFSARSDDLSSNIRSISVSTSDDGFSSCS----DGLQEEELQETVRQGSSVIERNARIIKWLYSCRNAAESGKTLRDLD-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * .. . . .. ******** :.:**: . . . * .:. * :.*:. : **:::******::** * * * :* : .. : .: .: :.. * .. . .: * . . : . *: **.**:***** *: *.**:***** :::*:**:***:* ** :: ::**:*:::*...** * :******* * * . :**:**********::*::* *: . . ", "identical_positions": 89, "similar_positions": 83, "identity": "19.96%" }, { "cls_id": "homologset.agr.HGNC:33342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UW43-1", "uniprot_id": "SG11B_MOUSE", "id": "Q3UW43-1", "name": "Sperm-associated antigen 11B", "aln": "-----------------------------------------------------------------------------------MIPRLLPFFASLLFAALLFP--------------------GLSNASSINHLVTEPPSFPKDEFPARGVNGSQLLHHRVKR--LPPRTPPYHE-------PEPNYQIVNCKKSEGQCQEYCNFMETQVGYCSKKKEPCCLHPF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F947-1", "uniprot_id": "F7F947_RAT", "id": "F7F947-1", "name": "Beta-defensin-like domain-containing protein", "aln": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKR--FPPRTPPYHE-------PGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDA7-1", "uniprot_id": "SG11A_HUMAN", "id": "Q6PDA7-1", "name": "Sperm-associated antigen 11A", "aln": "-----------------------------------------------------------------------------------MRQRLLPSVTSLLLVALLFP--------------------GSSQARHVNHSATEALGELRERAPGQGTNGFQLLRHAVKRDLLPPRTPPYQVHISHQEARGPSFKICVGFLGPRWARGCSTGNEKYHLPYAARDLQTFFLPFW", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **** ...**:.***:* * *.* :** .**. . ::. *.:* ** **:* *** :*******: *.::* . .: .. *. : :. : ** ", "identical_positions": 40, "similar_positions": 32, "identity": "17.7%" }, { "cls_id": "homologset.agr.HGNC:33345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTT0-1", "uniprot_id": "D3ZTT0_RAT", "id": "D3ZTT0-1", "name": "", "aln": "MDLN-CTGGLLEKEARRRRIILNQSQKDTLRVWFEKNPNPDLATRGHLAKKLGISESQIMTWFQKHRKIRKQVEFECCSEESQEQGQDKP-------RVKEAGRSRTHFTKFQIDILIEAFEKNRFPGIVTREKLAQETGIPESRIHIWFQNRRARHPDPKQGTRATSHPPESSQCPAQKT------------TGQLAPSKDPTSSCSVILPLSPPHTPNGPLDLSRGRQKQLPETTVLQPSQVVQRRGDDQNPSLFIDHLSEVKSPGEKEGFHTQAPLQLPIQKRGHNPSENSGLSVPPLEDSTQVSAVN---QHFRKPDQKDLAFLQHWDEWFQSMLAEWMPDKGYWAVKTDLHPWQAQLLQLLYVSEQTDQTPQQPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1W2PPF3-1", "uniprot_id": "DUXB_HUMAN", "id": "A0A1W2PPF3-1", "name": "Double homeobox protein B", "aln": "MNLEGTSGGILQKEFWRNRIQYNQSQKDILQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYRVKQRKLDYKCFSEKDQTQGHDQSQHLTQEYLPKEARQKQTFITWTQKNRLVQAFERNPFPDIATRKKLAEQTGLQESRIQMWFQKQRSLYLKKSRMEPMNLLVDDPNERPDATVGWHPINLFLPTDSSHYFSCSHSSSGHETLPPVLP--STQAPWDPFRFHVSQGPNVMIMQPTQAVQEGEKSDQPLIIPNHLLTL--PILTKDLDTPTPFWLQYQEEHQNHKEHSGSGVPQVKSHSQPEPEHREQQPLNLGQFDISNILQRWDEICQALLAEWDPLKGTH-------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*: :**:*:** *.** ****** *: **:::* ** *:* :***::*:.**:* .**:::* :::::::* **:.* **:*:. *** :.:*.:* * : *::***:* **.*.**:***::**: ****::***::*: : . .: . :..: * .. :.: .....:*. ..: *: * :.:.* * * : .* *:. ::**:*.**. ..::* :: :** : * .:.:.* :*: * *:. :* .*:** .** ::. :* .. : * :. : . :**:*** *::**** * ** ", "identical_positions": 113, "similar_positions": 127, "identity": "29.74%" }, { "cls_id": "homologset.agr.HGNC:3335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35912-1", "uniprot_id": "EMP3_MOUSE", "id": "O35912-1", "name": "Epithelial membrane protein 3", "aln": "MSLLLLVVSALHILILVLLFVATLDKSWWTLPDKESLNLWYDCTWNTTTQTWACSNVSENGWLKAVQALMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSAAVFSGALIYAIHTEEILAKHPSG--GSFGYCFALAWVAFPLALVSGTVYIHLRKRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYW5-1", "uniprot_id": "EMP3_RAT", "id": "Q9QYW5-1", "name": "Epithelial membrane protein 3", "aln": "MSLLLLVVSALHILILVLLFVATLDKSWWTLPEKESLNLWYDCTWNTTAKTWACSNVSENGWLKAVQALMVLSLILCCLSFILFMIQLYTMRRGGLFYATGLCQLCTSAAVFSGALIYAIHAKEILAKHPSG--GSFGYCFALAWVAFPLALVSGIIYIHLRKRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54852-1", "uniprot_id": "EMP3_HUMAN", "id": "P54852-1", "name": "Epithelial membrane protein 3", "aln": "MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESLNLWYDCTWNNDTKTWACSNVSENGWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAIHAEEILEKHPRG--GSFGYCFALAWVAFPLALVSGIIYIHLRKRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9B4-1", "uniprot_id": "E7F9B4_DANRE", "id": "E7F9B4-1", "name": "Epithelial membrane protein 3", "aln": "MAFLLMSVTVLHLITLAMLFIATMEKSWWTLGDIQNTDLWYKCSYDNSSGTWLCASVNESEWLQSVQALMILSVILSSISFMVFLGQLFTMSKGGLFYFTGLCQLFAGFAAFAAVLIYTFQKREILQNDTELEKGRFGYCYILAWVCVPLLLVSGALYVHLRKRA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::**: *:.**:: * :**:**::****** :. :***.*:::. : ** *:.*.*. **::**.**:**:**..:**::*: **:** :***** ****** :. *.*:..***::: .*** :.. * ****: ****..** **** :*:***** ", "identical_positions": 83, "similar_positions": 55, "identity": "50.3%" }, { "cls_id": "homologset.agr.HGNC:33358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NK44-1", "uniprot_id": "GLOD5_HUMAN", "id": "A6NK44-1", "name": "Glyoxalase domain-containing protein 5", "aln": "-MLRHLPSRLPVKMWGRTLEKQSWRDSSQ---TPPPCLIRRLDHIVMTVKSIKDTTMFYSKILGMEVMTFKEDRKALCFGDQKFNLHEVGKEFEPKAAHPVPGSLDICLITEVPLEEMIQHLKACDVPIEEGPVPRTGAKGPIMSIYFRDPDRNLIEVSNYISS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D8I3-1", "uniprot_id": "GLOD5_MOUSE", "id": "Q9D8I3-1", "name": "Glyoxalase domain-containing protein 5", "aln": "-------------MCDPTSESQLWRSSSQ---IPSPCLICRLDHIVMTVKNIEDTTMFYSKILGMEVTTFKGNRKALCFGDQKFNLHEVGKEFDPKAAHPVPGSLDVCLITEAPLEEVIERLKAFDVPIEEGPVFRTGAKGPILSIYFRDPDRNLLEVSSYVTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LL65-1", "uniprot_id": "A0ABK0LL65_RAT", "id": "A0ABK0LL65-1", "name": "Glyoxalase domain-containing protein 5", "aln": "-----------MVFWALT---TLWRTSSQ---TPSPCLICRLDHIVMTVKNIEDTTMFYSKILGMEVTTFKGDRKALCFGDQKFNLHEVGKEFDPKAAHPIPGSLDVCLITETPLEEVMKRLKAFDVPIEEGPVSRTGAKGPILSIYFRDPDRNLIEVSNYVTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q502D1-1", "uniprot_id": "GLOD5_DANRE", "id": "Q502D1-1", "name": "Glyoxalase domain-containing protein 5", "aln": "MALTLRVCSTFLRSCSSNSKSVLSGLSSVRFRSSCPVLISHLDHLVLTVRDLNKTTKFYSEVLGMEVVTFKGDRKALSFGEQKINLHQVGKEFEPKAQTPTPGSADLCLITKTPLKAVADHLKACGVTIEEGPVDRTGAVGPISSLYFRDPDDNLIEVSNYQQ-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** . * ** :***:*:**:.::.** ***::***** *** :****.**:**:***:*****:*** * *** *:****:.**: : .:*** .*.****** **** *** *:****** **:***.* ", "identical_positions": 84, "similar_positions": 30, "identity": "51.22%" }, { "cls_id": "homologset.agr.HGNC:3336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5Y4N8-1", "uniprot_id": "AGRE1_RAT", "id": "Q5Y4N8-1", "name": "Adhesion G protein-coupled receptor E2", "aln": "--------MWGFWLLLFWGFSGTHRWGMTTLAILGQRLNGVNECQDTTTCPAYATCTDTTESYYCTCKQGFLPSNGQTNFQGPGVECQDVNECL-----------------------------------------------RSDSPCGSNSVCTNIPGRARCSCLSGFSSSAGGSWILGSPGHFLCTDVDECLTIGICPK-------------NSNCSNSVGSYSCTCQSG--FVSNGSTCEDEDECVTRNACPEHATCHNTLGSYYCTCNEGLEFSGGGPMFQGLEESCEDVDECSRNSTLCGPSFICINTLGSYSCSCPAGFSLSTFQIPGHPADGNCTDIDECDDICPSNSSCTNTLGSYFCTCHPGFASSNGQLNFTDQEVTCEDID--ECTQDPFRCGRNSSCTNVPGSYNCSCLPDFRMDPGGSQAHGNFTCKRIPFKCKEDLIPKSEQIEQCQAGQGRNLDYTSFCTFVNATFTILDNTCENKSAPVSLQSA--------------ATSVSLMLEQASTWFEFSREETSTLGTILLETVESTMLAALLTPSGNASQTIRTEYLEIESKVINEECNEENVSIN----LKARGDKMDVGCFIIKESESTGTPGVAFVSFAHMDSVLDERFFEDGQA------------------------SWKLRMNSHVVGGTVTGERKEDFSKPIVYTLQHIQPKQKSERSICVSWNTDVEDGRWTPSGCETVEASETHTVCSCNRMTNLAIIMASG-------ELTMEFSLYIISYVGTVISLVCLALAIATFLLFR--AVQNHNTYLHLHLCVCLFLAKILFLTGIDKT----DNQTACAIIAGFLHYLFLACFFWMLVEAVMLFLMVRNLKVVNYFSSRNIKMLHLCAFGYGLPVVVVIISATVHPWGYGMHNRCWLNTETGFIWSFLGP---VCMIITINSALLAWTLWVLRQKLCSVNSEVSKLKDTRLLTFKAIAQIFILGCSWVLGIFQIGPL------ASIMAYLFTTINSLQGAFIFLIHCLLNRQVRDEYRKLLTRKTDLSSHSQTSGILLSSMPSTSKTG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61549-1", "uniprot_id": "AGRE1_MOUSE", "id": "Q61549-1", "name": "Adhesion G protein-coupled receptor E1", "aln": "--------MWGFWLLLFWGFSGMYRWGMTTLPTLGQTLGGVNECQDTTTCPAYATCTDTTDSYYCTCKRGFLSSNGQTNFQGPGVECQDVNECL-----------------------------------------------QSDSPCGPNSVCTNILGRAKCSCLRGFSSSTGKDWILGSLDNFLCADVDECLTIGICPK-------------YSNCSNSVGSYSCTCQPG--FVLNGSICEDEDECVTRDVCPEHATCHNTLGSYYCTCNSGLESSGGGPMFQGLDESCEDVDECSRNSTLCGPTFICINTLGSYSCSCPAGFSLPTFQILGHPADGNCTDIDECDDTCPLNSSCTNTIGSYFCTCHPGFASSNGQLNFKDLEVTCEDID--ECTQDPLQCGLNSVCTNVPGSYICGCLPDFQMDPEGSQGYGNFNCKRILFKCKEDLILQSEQIQQCQAVQGRDLGYASFCTLVNATFTILDNTCENKSAPVSLQSA--------------ATSVSLVLEQATTWFELSKEETSTLGTILLETVESTMLAALLIPSGNASQMIQTEYLDIESKVINEECKE-NESIN----LAARGDKMNVGCFIIKESVSTGAPGVAFVSFAHMESVLNERFFEDGQS------------------------FRKLRMNSRVVGGTVTGEKKEDFSKPIIYTLQHIQPKQKSERPICVSWNTDVEDGRWTPSGCEIVEASETHTVCSCNRMANLAIIMASG-------ELTMEFSLYIISHVGTVISLVCLALAIATFLLCR--AVQNHNTYMHLHLCVCLFLAKILFLTGIDKT----DNQTACAIIAGFLHYLFLACFFWMLVEAVMLFLMVRNLKVVNYFSSRNIKMLHLCAFGYGLPVLVVIISASVQPRGYGMHNRCWLNTETGFIWSFLGP---VCMIITINSVLLAWTLWVLRQKLCSVSSEVSKLKDTRLLTFKAIAQIFILGCSWVLGIFQIGPL------ASIMAYLFTIINSLQGAFIFLIHCLLNRQVRDEYKKLLTRKTDLSSHSQTSGILLSSMPSTSKMG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14246-1", "uniprot_id": "AGRE1_HUMAN", "id": "Q14246-1", "name": "Adhesion G protein-coupled receptor E1", "aln": "--------MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKG-NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECS-----------------------------------------------QSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPE-------------HSDCVNSMGSYSCSCQVG--FISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT--------------------------------------------------EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDID--ECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCENKTTVVSLKNT--------------TESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLD----LVAKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERFFKDHQAPLT-------------------TSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQPKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAVIMASG-------ELTMDFSLYIISHVGIIISLVCLVLAIATFLLCR--SIRNHNTYLHLHLCVCLLLAKTLFLAGIHKT----DNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGP---VCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPV------AGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASKTG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QH00-1", "uniprot_id": "A0A8M9QH00_DANRE", "id": "A0A8M9QH00-1", "name": "", "aln": "-----------MTMTDIILHKRFLKAPSTISVIMQDSTLILAFLMVTPVMSTAANLTDPCYNYTVLSDSWRSVNNTNNGYCDNSVSWSGWYRLFIN-----------------------------------------GLSAHIPDTCVAVFRCGTSYPLWIRGGHPTVQDGVVTRDVCGNTGGFCCYYGSYPIGVKACPGDYYVYELRSPTFCNSAYCADVGSVIISSTAATPVIITPDPCYTYTVLDDPWRADSSQPSKPVTKCDTSVSWSGWYRLFINGLNAHIPDTCVEQYSCGTEIALW------------------------------------IHGGHPTVEDGVVTRDVCGYAGGYCCFYGS-FPIRVKACPRNYYIYELLRPY--FCTSAYCAVVSNMSSISTTVTPQTSSAVINITLQEGCSNQSS-GCLKNLLEQIENITAQ-------------ELPLNTVTDILTVVFNASEKISVSSSSASPAQ--------------------------LASYGTKVLKSSEKLISTLVKPTETSANVSFTLAAVEGKVFMVGPQVTLD-KIPQLDTTNSSVDID----LIG----------IAKNNNDR--SAVAFMSYTTMENLLKADFFNTTND-------------------------TIKTMMSTVISATLPKTSNTALTKAVNFTFRHIREFEPSGSLSCVYWN----ISEWIVDGCSVLNSNSSHTVCSCVHLSTFALIMQTSSS-----PPPSD-LLELLGLVCVIVGLVFFSLALLSFALCQ--WSPGVNNVARINICISLLSAHLLFLLTQQFLSLIRPQQVLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQISSKKREVLSSGFLCVIGYVLAMVVVCVSIGLVPEGYGSE-HCWIKTDEGFIWSFLGP---VCVILALNLILFFKIVITLNSTLKNLNAEVSQMKQTKVMVFKTLGQFVVLGCPWILGFFTNG--------SEVLEIVFLIFNSQQGTFIFLIYCLLNNEIRQQYKNCFTCLCSGHSIKCNK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PZQ0-1", "uniprot_id": "A0A8M9PZQ0_DANRE", "id": "A0A8M9PZQ0-1", "name": "", "aln": "-------------MMHIYLLSLGLLFALIEHSIMQD-----------------------------CSDGYK----KQRGKCVD------------------------------------------------------------EDECEQELICGE----------------------------------------------------------NSNCYNTVGSYYCQCHTG-------------------FIPEGTKPTVNFTRADG-IQCKDFNECLNTSINCGPNAECVNN------------------------------------------------------------------EGGYACICR-------------------------------TGYTPNNGKQTFFVGQGVQCDDLKGALQEGCTNHTAKVCLENLLEQTENIKDE-------------ELSLDTVTSLLSMVLDAAVNIHMSSSSANPNE--------------------------LTSYGNRVLINNEELMSTLVKQTDTSANVSFTLADVEGRVFMVGPHVTLD-EIPRLHTRNCSIDID----LIG----------IANNNNGTRSAAVIFLGYNTMENLLKADFFNATND-------------------------TVNTMMSSVISVTLPKTTNTALSKPVNFTFRHIREFDPSGSFSCVYWN----ISKWIVDGCSVLNTNRSFTVCSCVHLSTFALIMQTRSH-----PPESDSLLNVLNVVCVIVGLLFFSLALLTFTRCQ--WSPGVNNVARINICISLLLAHLLFLLTQQFLSLIRRQKVLCMLISGLLHFLFLSGFVWMFIEAVLLFICVKNLSQISSQMKNVLRNKLLCVIGYAVALVVVSISAAVVPNGYGSE-KCWIQMHKGFIWSFLGP---VTIIIALNVILFISIGFSLKSAFKKLNADVSQLNQTKIVMFKTLAQFVVLGCSWILGFFTNS--------SKVLEILFLILNSQQGTFIFLIYCVLNKGIRQEYRKLFTSLYSGLKPKNFNWSSENTEDSTIHGLQMK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVGAGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQLHHHHNHHGEDTASPTKPSSKLPAGGNATSPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTN-PTCVFWN--YIDHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQT----ETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLT-SDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. . . . : * . . :. : . . : : .. . : ::: . : : :: : : : :. .: . . : . : :. : * .: ::.:*. : . : * *:. : : ::..: *:.::: : ** *. * ** .:. :.::*** :::.:*::* : : :: : : :: : :*: :: . . .. : :.*: . *** . . * *: :** :*: *: **. : : . : . :.* :.: ** :* : * * . * : .:::: : * : .:. :: .. . : : : ..:. :: :.:*.. * . * : : * :*: * :**:::*: * :* :*:. . . . ", "identical_positions": 50, "similar_positions": 174, "identity": "2.91%" }, { "cls_id": "homologset.agr.HGNC:3337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LY89-1", "uniprot_id": "A0ABK0LY89_RAT", "id": "A0ABK0LY89-1", "name": "", "aln": "--------------------------------MCFGPCPSSRGDRVSGPRAQSGVAFVPGAGARRALGLFPRHFPVTFQRGGQFRGGPCPRPLHKGPAQPP-----ATALCQPRRCPFRATMRGVSCHLLLVLCFVPNLSGVGTQKASG--CARWCPPNSECESNRSCKCKPG----FNSSSPDGLITNPAQSCEDINECI-QTDNLCGPYAMCMNSEGSYY--------------------CVCNLGYKLLSGAESFTNKSENTCQASVDTGMIPVPSSIHTVPTAR-KLPEQP----------TTVHPRTQLGDSGERTPKDVNECTSGQNQCHQSTHCINKMGGYSCICRRG------------WKPAPGSPNGPVNTVCEDVDECSSGQHQCHSSAICKNIP--------------------GSYKCRCPPGWIAIPRDKPN--NTVCQEP--HFPTWTLLPTAHSQALLSFSVEVQNLLRDFNPATVNYTIQKLIEAVDKLLEMPMDIG----TQTQQVATQLLSNLEQSLRTLAQFLP---------------KGPFTYKSP-SNTELALMVKEQDNKDVTTVHHSQAWMQLD---WAVTAGAKSSENGYSVAGILSSPNIQKLLANTSLNLE-----------QKRDTLEDLYGSPVQSVTLTFLSNINAIFLTNTDTEKLASDVTFKFNLTSVKSLKAREELMCAYWKSHDNGSGSWATDGCSMNDTG----FCHCNHLTSFAVLMAQYHVQ----------DPRLELITKVGLLLSLVCLLLCILTFLLVKPIQSSRTMVHLHLCICLFLGSVIFLVGVENEGGEVGLRCRLVAMLLHFCFLAAFCWMALEGVELYFLVVRVFQGQGLSTWHRCL------VGYGVPLLIVAIS-AAARMDGYGHATYCWLDFRKQGFLWSFSGPVAFIIFCNAAIFVITVWKLTKKFSE--INPNMKKLRKARVLTITAIAQLLVLGCTWGFGLFLFN------PHSTWLSYIFTLLNCLQGLFLYVTLCLLNKKVREEY------WKWACMVTGNKYTEFTSSTTGTGTSQTRTLRPSESGM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0M6-1", "uniprot_id": "AGRE5_MOUSE", "id": "Q9Z0M6-1", "name": "Adhesion G protein-coupled receptor E5", "aln": "-------------------------------------------------------------------------------------------------------------------------MRGVRCPGLLVVCILLSLSGAGTQKAESKNCAKWCPINSKCVSNRSCVCKPG----FSSEKE--LITNPAESCEDINECL-LPGFSCGDFAMCKNSEGSYT--------------------CVCNLGYKLLSGAESFVNESENTCQASVNTGTTPVPSRIHTVTTAPGNLPEQT----------TTVH-QTQMGDSEERTPKDVNECISGQNHCHQSTHCINKLGGYSCICRQG------------WKPVPGSPNGPVSTVCEDVDECSSGQHQCHNSTVCKNTV--------------------GSYKCHCRPGWKPTSGSLRGP-DTICQEP--PFPTWTLLPTAHSQTLLRFSVEVQNLLRDFNPATVNYTIQKLIEAVDKLLEDPMET------QTQQVAAQLLSNLEQSLRTLAQFLP---------------KGPFTYTSP-SNTELSLMVKEQDNKDVTTVHHGQTWMELD---WAVTAGAKISENGSSVAGILSSPNMEKLLGNTPLNLE-----------QRRASLEDFYGSPIPSVSLKLLSNINSVFLTNTNTEKLASNVTFKFDFTSVESIEPRHELICAFWKAH-NGNGYWDTDGCSMNGTG----FCHCNHLTSFAILMAQYHVQ----------DPRLELITKVGLLLSLICLLLCILTFLLVKPIQSSRTMVHLHLCICLFLGSIIFLVGVENEGGEVGLRCRLVAMMLHFCFLAAFCWMALEGVELYFLVVRVFQGQGLSTWQRCL------IGYGVPLLIVAISMAVVKMDGYGHATYCWLDFRKQGFLWSFSGPVAFIIFCNAAIFVITVWKLTKKFSE--INPNMKKLRKARVLTITAIAQLLVLGCTWGFGLFLFN------PHSTWLSYIFTLLNCLQGLFLYVMLCLLNKKVREEY------WKWACMVTGSKYTEFNSSTTGTGTSQTRALRSSESGM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHX3-1", "uniprot_id": "AGRE2_HUMAN", "id": "Q9UHX3-1", "name": "Adhesion G protein-coupled receptor E2", "aln": "-------------------------------------------------------------------------------------------------------------------------MGGRVFLVFLAFCVWLTLPGAETQDSRG--CARWCPQDSSCVNATACRCNPG----FSSFSE--IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYD--------------------CVCSPGYEPVSGAKTFKNESENTCQDVDECQQN--PRLCKSYGTCVNTLGSYT----------CQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPG------------WQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTV--------------------GSYSCRCRPGWKPRHGIPNNQKDTVCEDM--TFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS---------------NGLLNFSYP-AGTELSLEVQKQVDRSVT-LRQNQAVMQLD---WNQAQ--KSGDPGPSVVGLVSIPGMGKLLAEAPLVLEP----------EKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHR---SVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEE--------DPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYL-FLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAIS-AASRPHLYGTPSRCWLQPEK-GFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSS--LNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVG------PAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQY------GKWSKGIR--KLKTESEMHTLSSSAKADTSKPSTVN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B737-1", "uniprot_id": "A0A8M2B737_DANRE", "id": "A0A8M2B737-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------MELKWAFILGLFLPSCSG-------------------------CALG----YKFVKR---KCVDEDECETPGMCG---------DAQCVNTDGSYY--------------------CTCAAGFKMS---------QTGPCKDINECLED--ELICPAQMRCENTFGSYV----------CVCPTGHQWKN--EAECEDEDECLS--SPCGLHRSCFNTPGSFVCKCSPG------------FRELEGG-------MCADINECSESPDVCGTNGDCINNP--------------------GGFSCRCHQGFTNYGNNQSKCIEMSCDQFK-PEPDAGNTPEKLKHLMSLLMNSCKSLN---DPHGEHFTAEKLLENLCNSTDDLLSEGN---VADGETLSVFLDAVENSMRLIGPQLK---------------DPVTKMETQNTYAEVAVTRNQTPPSGSVTLSTGSAHFNTS---WETVVG--KSYPGFAFVALVSYKDMNSSSDLFNSMAR------------------EKSDVKEKQITYKLNSKVVTAVVSNPDTKHLSKPVTLIFTHEEKRAESEGVAYSCVYWSES---ERGWSGRGCELAWSNSTHTACSCSHLSSFAVLMALYPVED---------TFELVVITRVGLVLSLICLILCILTFRFCRSIQGTRNSIHLHLSVCLFIADLVFLCGISSTHNQV--ACAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVLVFHTTLKHLYMYAV-------GYGVPLVIVSIS-AIAVPKGYGTDRHCWLSLEG-YLILSFFIPVCIIVILNITVFIITVWKLALKFSS--LNPDLSKLHKIRSFLATAVAQLCVLGGSWVFGFFLFQK-----NGTEVMLYLFIILNSLQGALIFIMHCLLSKQVRVEYR-----SLFMRMCSNKKKGDYSVSSTEPSHSSQKPLQIDQSTGESTI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVGAGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQLHHHHNHHGEDTASPTKPSSKLPAGGNATSPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTN---PTCVFWNYI---DHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSI--FCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVN--CYYLLSYGLSLSVVAIS-LVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . * :. .. : :. * : . . : . : * .: . . . :. *. * : .. . .... . .. * :* : : . . : : : . : : : : : *: :* * . .: : : . . .. :. . . . * : : : . : . : *.: : : : :*:. :*: : *.:*. * **. : * *.**:.**:** . : : :*: : :: : * *.: ::.: . :: : :**: ::** .:.. .: * ::: ** *: *: *.. . .**:. *:** * * * : * ** :. .:: : : . : . * . * : . * :*. * . : . : * * :* * * ::: *: .:::* :* : . . . . . . ", "identical_positions": 64, "similar_positions": 171, "identity": "3.72%" }, { "cls_id": "homologset.agr.HGNC:3338", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60598-1", "uniprot_id": "SRC8_MOUSE", "id": "Q60598-1", "name": "Src substrate cortactin", "aln": "MWKASAGHAVSIT-QDDGGADDWETDPDFVNDVSEKEQRWGAKTVQGSG-HQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDRSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKG----------FGGKFG-VQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSSAVGFDYKERLAKHESQQDYAKGFGGKYGVQKDR---MDKNASTFEEVVQVPSAYQKTVPIEAVTSKTSNIRANFENLAKEREQEDRRKAEAERAQRMAKERQEQEEARRKLE------EQARAKKQTPPASPSPQPIEDRPPSSPIYEDAAPFKAEPSYR----GSEPEPEYSIEAAGIPEAGSQQGLTYTSEPVYET---TEAPGHYQAEDDTYDGYESDLGITAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HL2-1", "uniprot_id": "SRC8_RAT", "id": "Q66HL2-1", "name": "Src substrate cortactin", "aln": "MWKASAGHAVSIT-QDDGGADDWETDPDFVNDVSEKEQRWGAKTVQGSG-HQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKG----------FGGKFG-VQTDRQDKCALGWDHQEKLQLHESQK-------------------------------------DYAKGFGGKYGVQKDR---MDKNASTFEEVVQVPSAYQKTVPIEAVTSKTSNIRANFENLAKEREQEDRRKAEAERAQRMAQERQEQEEARRKLE------EQARAKKQTPPASPSPQPAEDRPPSSPIYEDAAPLKAEPSYG----SSEPEPEYSTEAAGLPEASNQQGLAYTSEPVYET---TEVPGHYQAEDDTYDGYESDLGITAIALYDYQAAGDDEISFDPDDVITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14247-1", "uniprot_id": "SRC8_HUMAN", "id": "Q14247-1", "name": "Src substrate cortactin", "aln": "MWKASAGHAVSIA-QDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSG-HQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKG----------FGGKFG-VQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDR---MDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEARRKLE------EQARAKTQTPPVSPAPQPTEERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYES---AEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABE6-1", "uniprot_id": "A0AB13ABE6_DANRE", "id": "A0AB13ABE6-1", "name": "", "aln": "MWKAAAGQSVSMS-VDEG-ADDWETDPDFENDVSEKEQRWGAKTVQGSG-HQEHINIHKLRQTVSTEHSDLKQKELATMPKASHGYGGKFGLQQDRMDKSAVGHEYQSKLSKHCSQTDTSKGFGGKYGLQEDRVDQSAVGFEYVGKTEKHASQKDYSTGFGGRYGVQADRVDQSAVGFEYQGKTEKHESQKDYAKGFGGKFGVETDKVDKSAMGFEYQGKTEKHESQKDYVKG----------FGGKFG-VQTDRQDKSAVGWDHQEKLQLHESQK-------------------------------------DYSKGFGGKYGVQKDR---MDKSAGTFEEVQKPSAAYQKTRPVEAASSSASSIKARFENIAKQKEEEEQQRLEEERSRRQAKEKQEQEEAR------------THMKTQEEPASVCS--VEN---GSHVYELEQ-HTAEHTHE------EP----------------------PQEDLYQN---TEP----DTGAESY-EYAEDVGITAVALYDYQAAGDDEISFDPDDIITNIEMIDEGWWRGVCRGAYGLFPANYVEVRQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDF4-1", "uniprot_id": "Q9VDF4_DROME", "id": "Q9VDF4-1", "name": "", "aln": "MWKASAGHQIQATSAASAEDDDWETDPDFVNDVSEQEQRWGSKTIDGSGRTAGTIDMDKLREETEQADLDKK-KQLLKDQNAGYGYGGKFGVEKDRMDKSAVGHDYQGKVGKHASQKDYSDGFGGKFGVQEDRKDKSAVGWDHVEKVEKHASQKDYATGFGGKFGVQSDRVDKSAVGWDHIEKVEKHESQKDYSKGFGGKFGVQEDRKDKSAVGWDHKEAPQKHASQVDHKVKPVIEGAKPSNLRAKFENLAKNSEEESRKRAEEQKRLREAKDKRDREEAAKKTVAENTPR------------------TSTEAPPPKGSRAAIQTGRTGGIGNAISAFNQMQSPVSETPPARKEPIIIPKAQPVKIELEAKEEPTASTTSAAVAPTPTVVPAREPETAPVAKAAAPPPDVVPQIEVETVDTPPRSEPQSPVYVPTPQPEVHAQVQVQPEPQPQADPEPVVEEEPLYQNQAEIKAASPLPPTNGTVSEAVAPSGTATVPEEAIYANSDNLADYLEDTGIHAIALYDYQAADDDEISFDPDDVITHIEKIDDGWWRGLCKNRYGLFPANYVQVVGQNS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**: :. : .. ********* *****:*****:**::*** *::.***: . . * *:* . :*.:*******:::****:*****:**.*:.**.** * *****:*:* ** *:****::: *.*********::****::***:****:****::: *.******:**:******:*:: *: ****:*:::: .:** ** *: : .** : .: :::. :.*::*: :.:: : . *.: .:*..* :.: .:*::: . : : ..:. :: .:* : . : *:* : *: . : * * . :: . * * : . : : .. * .* ** *:********.**********:**:** **:*****:*:. *********:: ", "identical_positions": 188, "similar_positions": 136, "identity": "32.53%" }, { "cls_id": "homologset.agr.HGNC:33383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A275-1", "uniprot_id": "D4A275_RAT", "id": "D4A275-1", "name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase", "aln": "MKLRSKAAALLLLALAVLLLALLSLRARQDLEPPGFPARPEAAPQRRHAPVPTLPPEPRAFPGAAGPRFPRRRPPRLRPGASRPRAASRGKLARRSGEVRSLHSV-PPELWIHLAVVACGNRLEETLVMLKSAVLFSH--RKMRFHIFTEDALKPEFDKQLRQWPDSYTKKFEHKLYPITFSVGNPQEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPVDDIWKLLRQFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSTQFKNSLIPTGLAWEEMLLPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCKEAEREGVSVLHGNRGVYHDDKQPTFRALYEAIRDFPFRDNLFQSMYYPLQ--LKFLETVHTLCGRIPQVFLKQIEKTMRRAYEKHIVIHVGPNPMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810K9-1", "uniprot_id": "GXLT2_MOUSE", "id": "Q810K9-1", "name": "Glucoside xylosyltransferase 2", "aln": "MKLRSKAAALLLLALAVLLLALLSLRARRDPEPPGFPARPEAAPQRRHAPVPTLPPEPRAFPGAAGRRSPRRQPPRLRPRAGRPRAASREKLARRPGETRSLHSV-PPELWIHLAVVACGNRLEETLVMLKSAVLFSH--RKMRFHIFTEDALKPEFDKQLRQWPDSYTKKFEHRLYPITFSVGNPQEWKKLFKPCAAQRLFLPAILKDVDSLLYVDTDVLFLRPVDDIWKLLRQFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRNTQFKNSLIPAGLAWEEMLLPLYQKYKSAITWGDQDLLNIIFYYNPECLYVFPCQWNYRPDHCMYGSNCKEAEREGVSVLHGNRGVYHDDKQPTFRALYEAIRDFPFQDNLFQSMYYPLQ--LKFLETVHTLCGRIPQVFLKQIEKTMRRAYEKHVIIHMGPNPMS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PJZ3-1", "uniprot_id": "GXLT2_HUMAN", "id": "A0PJZ3-1", "name": "Glucoside xylosyltransferase 2", "aln": "MKLRSKAAALLLLALAALLLALLSLRAGR-AEPPALPARPASAPQRHPAPVPARWPGPGALPGAS-PGVRRRRPPRPRPRAGRRGAARLEKLARRPGEPRSFQAVLPPELWIHLAVVACGNRLEETLVMLKSAVLFSH--RKIQFHIFTEDSLKPEFDKQLRQWPDSYTKKFEHRIYPITFSVGNPQEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPVDDIWKLLRLFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSTQFKNSMIPTGLAWEDMLYPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCREAEHEGVSVLHGNRGVYHDDKQPTFRALYEAIRDFPFQDNLFQSMYYPLQ--LKFLETVHTLCGRIPQVFLKQIEKTMKRAYEKHVIIHVGPNQMH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBY3-1", "uniprot_id": "Q9VBY3_DROME", "id": "Q9VBY3-1", "name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase", "aln": "------MQHLHMCLLCLIALAILSYFVHQ---------RPSWVTENK-----------GKMLGYN--ELQTGKPP------------------------------------LYIVVVSCGQRVQETLVMIKSAILFNYDEEYLKFVIFTEDGKGDEFREKLTDWRDIKPFTFDFEILPLKFPSGNEVEWRNLFKPCAAQRLFLPSLLTHVDSLLYVDTDILFLSPISDIWRFFKKFNETQMSALTPEHENENIGWYNRFARHPFYGRLGVNSGVMLMNLTRMR-----------EMKWEQHIVSIHKEYKLRIIWGDQDIINILFYYHPDKLYIMPCEYNYRPDHCMYMSICNMS-QTGVKVIHGNRGYFHSDRQPLFKSIYGAMENYQLGSNANTEFLMPLHAALSIPSIKNSSCGKISNEVLKVANAVVTKRYREV-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *. : **:** . : ** ..:.: : * :** :::.**:**:*::*****:***:**.: . ::* *****. ** ::* :* * . .*:..: *:.*. ** **::************* :*..**********:*** *:.***:::: **.**::*::**** :****.********* *************:* : **: : .::::** * *****::**:**::*: **::**::********* * *. : : **.*:***** :*.*:** *:::* *:.:: : .* .: **: *.: . :: **:*.: .** : .: : *.: ", "identical_positions": 166, "similar_positions": 114, "identity": "36.97%" }, { "cls_id": "homologset.agr.HGNC:33391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q561R8-1", "uniprot_id": "CAHM6_RAT", "id": "Q561R8-1", "name": "Calcium homeostasis modulator protein 6", "aln": "MEKFKAVLDLQIKHRSALGYGLVTLLTAGGEKIFSTVVFQCPCTATLNLTYGLVFLLVPALALFLLGYALSARTWRLLTGCCSRSASTRSSSGLRSTLVCAQVSAVAALAPLTWVAVALLGGSFYQCAVSGSTRLASYLCKDRNHSCIAKLPQVPCNKQEA-EMQEILSQLKAQSQVLGWVLIAAVIFLLLVFKCVSRCFSPVSYLQLKFWEIYLEKEKQILQSQAAEHATQLARENIRSFFECSKPKECNTPSRKDWQQISALYTFNSKNQFYSMLHKYVSRKEVSSSLHSVEGDVVVPVLGFVDDAAMANTHGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C9E8-1", "uniprot_id": "CAHM6_MOUSE", "id": "Q8C9E8-1", "name": "Calcium homeostasis modulator protein 6", "aln": "MEKFKAVLDLQRKHRNALGYSLVTLLTAGGEKIFSSVVFQCPCTATWNLPYGLVFLLVPALALFLLGYALSARTWRLLTGCCSRSA--RFSSGLRSAFVCAQLSMTAAFAPLTWVAVALLEGSFYQCAVSGSARLAPYLCKGRDPNCNATLPQAPCNKQKV-EMQEILSQLKAQSQVFGWILIAAVIILLLLVKSVTRCFSPVSYLQLKFWEIYWEKEKQILQNQAAENATQLAEENVRCFFECSKPKECNTPSSKDWQEISALYTFNPKNQFYSMLHKYVSREEMSGSVRSVEGDAVIPALGFVDDMSMTNTHEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R3K3-1", "uniprot_id": "CAHM6_HUMAN", "id": "Q5R3K3-1", "name": "Calcium homeostasis modulator protein 6", "aln": "MEKFRAVLDLHVKHHSALGYGLVTLLTAGGERIFSAVAFQCPCSAAWNLPYGLVFLLVPALALFLLGYVLSARTWRLLTGCCSSAR-ASCGSALRGSLVCTQISAAAALAPLTWVAVALLGGAFYECAATGSAAFAQRLCLGRNRSCAAELPLVPCNQAKASDVQDLLKDLKAQSQVLGWILIAVVIIILLIFTSVTRCLSPVSFLQLKFWKIYLEQEQQILKSKATEHATELAKENIKCFFEGSHPKEYNTPSMKEWQQISSLYTFNPKGQYYSMLHKYVNRKEKTHSIRSTEGDTVIPVLGFVDSSGINSTPEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*****: **:.****.**********:***:*.*****:*: **.******************.************** : .*.**.::**:*:* .**:*********** *:**:**.:**: :* ** .*: .* * ** .***: :. ::*::*.:*******:**:***.**::**:...*:**:****:******:** *:*:***:.:*:*:**:**.**::.*** *:*** **** *:**:**:*****.*.*:********.*:* : *::*.***.*:*.*****. .: .* :", "identical_positions": 199, "similar_positions": 87, "identity": "62.97%" }, { "cls_id": "homologset.agr.HGNC:3340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV90-1", "uniprot_id": "D3ZV90_RAT", "id": "D3ZV90-1", "name": "", "aln": "---------MCQAWCTPRTAAAPGHRAFPRAPLPHSSSAAATMFQPATKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEP---------------------------------------------------------------------LRPTALNYPHPSAAETAFVSGFPAAAAAGASRSLYGGPELVFPEAMNHPALTVHPAHQLGSSSLQPPHSFFSAQHRDPLHFYPWVLRNRFFGHRFQASEVPQDGLLLHG---------------------------------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS-----------------HHINRWRIATKQANGEDIDVTSND----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04742-1", "uniprot_id": "EMX1_MOUSE", "id": "Q04742-1", "name": "Homeobox protein EMX1", "aln": "------------------------------------------MFQPAAKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEP---------------------------------------------------------------------LRPTALNYPHPSAAETAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGSSSLQPPHSFFSAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHG---------------------------------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS-----------------HHINRWRIATKQANGEDIDVTSND----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04741-1", "uniprot_id": "EMX1_HUMAN", "id": "Q04741-1", "name": "Homeobox protein EMX1", "aln": "---------MCLAGCTPRKAAAPGRGALPRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEP---------------------------------------------------------------------LRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHG---------------------------------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS-----------------HHINRWRIATKQANGEDIDVTSND----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q804S6-1", "uniprot_id": "EMX1_DANRE", "id": "Q804S6-1", "name": "Homeobox protein EMX1", "aln": "------------------------------------------MFSATGKRCFTIESLVAKE-----------------SPITLEDP---------------------------------------------------------------------IRPTALSY---SAPADSFLNGYQSP----AGRALYPNPELVFSETVNHAPLSMHP-HQLGSAPLQHPH-FFGTQHREPLNFYPWVLRNRFFGHRFQGNDVSQDTLLLHG---------------------------------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLANSLSLSETQVKVWFQNRRTKYKRQKLEEEGPECTQKKKGN-----------------HHINRWRIATKQTGSEDIDVMSDA----------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFQ3-1", "uniprot_id": "Q9VFQ3_DROME", "id": "Q9VFQ3-1", "name": "", "aln": "MVTCGRQTFNMLPMAPTSPFVSSSSSVAASSTSVSASSTVSASASSKPKLAFSIDSIVGESSTRSAPLRVSVISSPPPRSESPASPTNTNNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQLLQQHQQHLQQQHHQQQQHFIQQQQQLYLREREREREREREREREKSRERENQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * *:*:*:*.:. : .* :** .* : . : . :. * :: .: ..*: * :* * * .. * :: * : :* : .. . . .* *****:******:***:**:*** ************* .***:**************:** : * . . :.:**. : :. * . . ::*: .: ", "identical_positions": 75, "similar_positions": 62, "identity": "14.31%" }, { "cls_id": "homologset.agr.HGNC:3341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCK7-1", "uniprot_id": "D3ZCK7_RAT", "id": "D3ZCK7-1", "name": "", "aln": "----------------------------------------MFQPAPKR--CFTIESLVAKD----------------SPLPASR----SEDPIRPAALSYANSSP------------------------------------------------------------INPFLNGFHSAAAAAA-------------------------------------------------------AGRGVYSNPDLVFAEAVSHPPN------------------------------PAVPVHPVP----------------------PPHALAAHPLPSSHSPHPLFASQ--------------------------------------QRDPSTFYPWLIHRY-RYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKG---------------THHINRWRIATKQASPEEIDVTSDD------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04744-1", "uniprot_id": "EMX2_MOUSE", "id": "Q04744-1", "name": "Homeobox protein EMX2", "aln": "----------------------------------------MFQPAPKR--CFTIESLVAKD----------------SPLPASR----SEDPIRPAALSYANSSP------------------------------------------------------------INPFLNGFHSAAAAAA-------------------------------------------------------AGRGVYSNPDLVFAEAVSHPPN------------------------------PAVPVHPVP----------------------PPHALAAHPLPSSHSPHPLFASQ--------------------------------------QRDPSTFYPWLIHRY-RYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKG---------------THHINRWRIATKQASPEEIDVTSDD------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04743-1", "uniprot_id": "EMX2_HUMAN", "id": "Q04743-1", "name": "Homeobox protein EMX2", "aln": "----------------------------------------MFQPAPKR--CFTIESLVAKD----------------SPLPASR----SEDPIRPAALSYANSSP------------------------------------------------------------INPFLNGFHS-AAAAA-------------------------------------------------------AGRGVYSNPDLVFAEAVSHPPN------------------------------PAVPVHPVP----------------------PPHALAAHPLPSSHSPHPLFASQ--------------------------------------QRDPSTFYPWLIHRY-RYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKG---------------THHINRWRIATKQASPEEIDVTSDD------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18488-1", "uniprot_id": "EMS_DROME", "id": "P18488-1", "name": "Homeotic protein empty spiracles", "aln": "----------MTKMIPP----------------VPTAAAAVMMPTPKQKIGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNVPGSPPQTPPATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQHLQAPHPHPHLSPAQQHVLHQHLLMQQQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSLKRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKAL-PPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPG------SFLVP--PFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRN---------------MHNGSGDEDDDELIDMEMDECPSDEEH----------ELDASH------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFQ3-1", "uniprot_id": "Q9VFQ3_DROME", "id": "Q9VFQ3-1", "name": "", "aln": "MVTCGRQTFNMLPMAPTSPFVSSSSSVAASSTSVSASSTVSASASSKPKLAFSIDSIVGES------------STRSAPLRVSVISSPPPRSESPASPTNTNNSGRRTPRG--------------------------------YIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGN------------------------------------------------TAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAG-----------PPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPG--------HPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIFP-RFPG------NFLFQ--PFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQLLQQHQQHLQQQHHQQQQHFIQQQQQLYLREREREREREREREREKSRERENQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.* *:*:*:*.:. :* . . **: : .* . .* *. . . * *: . . . * * :* * .. . *.** .. **. :****: *: * : ** * .**. *****:******:***:****** *:******** **:.*.*:**************.** : * ... .::. *. . : : .*: ", "identical_positions": 85, "similar_positions": 61, "identity": "13.2%" }, { "cls_id": "homologset.agr.HGNC:3342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT82-1", "uniprot_id": "A0A0G2JT82_RAT", "id": "A0A0G2JT82-1", "name": "Homeobox protein engrailed-like", "aln": "----------------------MEEQQPEPKSQRD--------------------SGLGAVAAAAAVVAAAAPGGLSLSLSPGASGSSGS--DGDSVPVSPQPAPPSPPAAPCLP---------PLAHHPHLPPHPPPPPPPPPPPPPPQHLAAPAHQPQPAAQLHRTTN----FFIDNILRPDFG----------------------------------------CKKEQPLPQLLVASAAAGGG------AAGGGSRVERDRSQTGAGRDPV-------------------HSLGTRASGAASL--LCAPDANCGPPDGSQPATAVGAGASKA----GNPAAAAAAAAAAAAAAVAAAAAAASKPSDSGGG-SGGSAGSPGAQGAKFPEH-NPAILLMGSANGGPVV---KTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKN--EKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09065-1", "uniprot_id": "HME1_MOUSE", "id": "P09065-1", "name": "Homeobox protein engrailed-1", "aln": "----------------------MEEQQPEPKSQRD--------------------SGLG-------AVAAAAPSGLSLSLSPGASGSSGS--DGDSVPVSPQPAPPSPPAAPCLP---------PLAHHPHLPPHPPPPPPPPPPPP--QHLAAPAHQPQPAAQLHRTTN----FFIDNILRPDFG----------------------------------------CKKEQPLPQLLVASAAAGGG-----AAAGGGSRVERDRGQTGAGRDPV-------------------HSLGTRASGAASL--LCAPDANCGPPDGSQPATAVSAGASKA----GNPAAAAAAAAAAAAAAVAAAAAAASKPSDSGGG-SGGNAGSPGAQGAKFPEH-NPAILLMGSANGGPVV---KTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKN--EKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05925-1", "uniprot_id": "HME1_HUMAN", "id": "Q05925-1", "name": "Homeobox protein engrailed-1", "aln": "----------------------MEEQQPEPKSQRD--------------------SALG-------AAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPPAAPCLP---------PLAHHPHLPPHPPPPPP--------QHLAAPAHQPQPAAQLHRTTN----FFIDNILRPDFG----------------------------------------CKKEQPPPQLLVAAAARGG--------AGGGGRVERDRGQTAAGRDPV-------------------HPLGTRAPGAASL--LCAPDANCGPPDGSQPA-AAGAGASKA----GNPAAAAAAAAAAVA---AAAAAAAAKPSDTGGGGSGGGAGSPGAQGTKYPEHGNPAILLMGSANGGPVV---KTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKN--EKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04896-1", "uniprot_id": "HME1A_DANRE", "id": "Q04896-1", "name": "Homeobox protein engrailed-1a", "aln": "----------------------MEDQRRGQGEEED--------------------DSGS---------------------------------------------LPSPPLLP----------------------------------------------------AHRNTD----FFIDNILRPDFG----------------------------------------CKRER--------------------------ERVTRD-----SGVRPT-------------------ALPDSRSDGVSS-----SASSTVSSPVSSRQSNKVEQGSSKS----SSPS----------------------------------------------------------------------KDSQKQILWPAWVYCTRYSDRPSSGPRTRKLKKKNNNTESDDKRPRTAFTAEQLQRLKAEFQTSRYITEQRRQALARELGLNESQIKIWFQNKRAKIKKSSGFKNALAMQLMAQGLYNHSTTTIQEEEDN----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02836-1", "uniprot_id": "HMEN_DROME", "id": "P02836-1", "name": "Segmentation polarity homeobox protein engrailed", "aln": "MALEDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDK-TNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQIP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..*: .:.: . .*.* : .:. * *.*** ** .:::: *: .: .. .: . ..:. :. . . .* : :*:: ...: .:. : :******************* *: *: :: .::*******::*** *** **: .**:**:*** *: **.***:***************::* ** **::*********:*..: .:::. ", "identical_positions": 92, "similar_positions": 80, "identity": "16.64%" }, { "cls_id": "homologset.agr.HGNC:33426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60928-1", "uniprot_id": "GGT1_MOUSE", "id": "Q60928-1", "name": "Glutathione hydrolase 1 proenzyme", "aln": "--------------------------------------------MKNRFLVLGLVAVVLVFVIIGLCIWLP--------------------YTSGKPDHVYSRA----AVATDAKRCSEIGR---DILQEGGSVVDAAIASLLCMGLMNAHSMGIGGGLFFTIYNSTTGKVEVINAREVAPRLANTT---MFNNSKDSEEGGLSVAVPGEIRGYELAHQRHG--RLPWARLFQPSIQLARHGFPVGKGLAIALDKKRDVIEKTPALCEVFCRQGK---VLQEGETVTMPKLADTLQILAQEGAKAFYN--GSLTAQIVKDIQEAGGIMTVEDLN--------NYRAELIEHPMSIGLGDATLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPAAYYEPEFY-------LQDDGGTAHLSAVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFINQFRVAPSP-ANFIKPGKQPLSSMCPSIILD-KDGQVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKD--IDQVVTAGLKIRHHHTEVTPTFIAVVQAVVRASGGWAAASDSRKGGEPAGY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5MD39-1", "uniprot_id": "GGTL3_HUMAN", "id": "B5MD39-1", "name": "Glutathione hydrolase light chain 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSEFFAAQLRSQISDHTTHPISYYKPEFY-------TPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVCSPVSGILFNNEWTTSALPAFTNEFGAPPSP-ANFIQPGKQPLLSMCPTIMVG-QDGQVRMVVGAAGGTQITTDTALAIIYNLWFGYDVKRAVEEPRLHNKLLPNVTTVERN--IDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYR2-1", "uniprot_id": "Q9VYR2_DROME", "id": "Q9VYR2-1", "name": "", "aln": "--------------------------------------------MYIRIGLNSLISVVIVILVAVYIYRYPDGNAGKKKASRRPPNPEDPLPPSNSPLHRFSRA----AICSDSDVCSQLAK---KVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKENKSYSILAREMAPLALRADNFSSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFG--RLKWKDLVLPTLELCRRGYRLYKHQYDALILNQDMIRADSGLRRMFIDPDTGRFWPLGHLIRPAAQLCNTYDRLANEGPLSFYR--GSIADDLLADLKDAGSAITKEDLN--------QAHAKLSS-AIVMPLDEYDLHLTPPPGSGHVLGFIMNILKEFRAEFSRAGTMSPR--QIHLMVEAMKFGFVKRWQLDES-------ASEELLSNLTSHELAKSVARQINHTHTFNRPEFYGASPGIQIRDEHGTAHTSVLHGN-DAVSVTSSINFYFGSGRTGRRTGVIFNNAMSDFSIEQLKNYFDLPFVPGTNGVAPAARPMSSMCPVIVTERATGNVRLVVGAAGGTKIISALSPLLVRILWQEASIKAAIDASRIHHQMLPNVLLYEYG--LRQSYVDSLAERGHRCERYENRGSVICGIAQANDTIWVNSDFRKPGGVSGF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05902-1", "uniprot_id": "ECM38_YEAST", "id": "Q05902-1", "name": "Glutathione hydrolase proenzyme", "aln": "MLLCNRKVPKTLNTCFILHIFTLLTLGVLVSGMPSKMVSFASQETLQRINNLLRGSANRDVDIIAEYLKKDDDDDGGDKDHHNIDIDPLPRRPSLTPDRQLLKVGLHGAISSDLEVCSNLTINEVLLKFPGSNAADAAVTQALCKGMVNFFNSGIGGGGYVVFSGKDDEDHLSIDFREKAP--MDSHKFMFENCSLCSKIGGLAVGVPGELMGLYRLFKERGSGQVDWRDLIEPVAKLGSVGWQIGEALGATLELYEDVFLTLKEDWSFVLNSTHDGVLKEGDWIKRPALSNMLMELAKNGSVAPFYDPDHWIAKSMIDTVAKYNGIMNLQDVSSYDVHVTKPLSMKIRKGANFIPDNDMTVLTSSGSSSGAALLAALRIMDNFQNQ----EGGDYEKETTYHLLESMKWMASARSRLGDFEGEALPKHIEEVLDPEWALKAVKSIKRNSQDGNFKTLENWTLYDPAYDINNPHGTAHFSIVDSHGNAVSLTTTINLLFGSLVHDPKTGVIFNNEMDDFAQFNKSNSFELAPSI-YNFPEPGKRPLSSTAPTIVLS-ELGIPDLVVGASGGSRITTSVLQTIVRTYWYNMPILETIAYPRIHHQLLPDRIELESFPMIGKAVLSTLKEMGYTMKEVFP-KSVVNAIRNVRGEWHAVSDYWRKRGISSVY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : . . :: : **** * : . .**: *::**: *** . :*::**: : * * . * *. :*: * .* *: * :****:**::* : :: * : :: .*:*:::**: * : : * : : :*: .: .. . . ** : :. ", "identical_positions": 42, "similar_positions": 60, "identity": "6.28%" }, { "cls_id": "homologset.agr.HGNC:33429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M6Z9M8-1", "uniprot_id": "A0A8M6Z9M8_DANRE", "id": "A0A8M6Z9M8-1", "name": "", "aln": "MAFFKSFQQSLPSVSAMLESVTEKVDDLAFALSDVTYTVTGELAEHVNTIIHKVQAEELKRIRKKEAEEKEAAARQVQERRDTFLDRAKIQTQAASGLVEDPEPQIAKNDNCSVLSIETLSSESDLSQTPDMLIEKFKAQNSADALSVCQQNGSCIKETSESTKAKPSSPADGNEKKKSSSRDAEEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q58G82-1", "uniprot_id": "SY14L_HUMAN", "id": "Q58G82-1", "name": "Putative synaptotagmin-14-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEGFQILVQNTVQGTIHKIKCV------------------------------CDSQMSVSEMSCSESTSACQSLEDGSVPEILISLLYNATNGRLSAEVIKGSHLKNWAANRPPN-------------------TYVKLTLRKSTDQEMSKCKISIRRGRPNPVYKETFVFKVTLFQLSHVTLMLSVYNKSSMRRK-MIGWIYLGLNSSGEE-LNHWTEMKESKGRQVRRWQALLESR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .: * .: ::* *.: .*** *:*::****::*: * :**.****:.*:****.****.*******:** ***:*** ******* :* .******* *: **:***.*******:*:*****.***:****** **:** ***** ********* *.**********:** **::**** ", "identical_positions": 125, "similar_positions": 39, "identity": "18.17%" }, { "cls_id": "homologset.agr.HGNC:3343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8B1-1", "uniprot_id": "D3Z8B1_RAT", "id": "D3Z8B1-1", "name": "Homeobox protein engrailed-like", "aln": "-----------------------------------------------------------------------------------------------------------------MEEKDSKSSETAA--EAQRQPEPSPGGGSGGG------------------------SSPSD------------------------------------------------------------------------SDTGRRRALMLPAVLQAPGNHQHPHR------------------ITN----------FFIDNILRPEFG-RRKDAGTCCAGAGGARGG----EGGAGSTEGGGG-ADGAEQILG--ARESRPNPACAPSAGGPLSGASGDPAADGEG--GSKTLSLHGGAKKPGDPGGSLDGALKARGLGGGDLSVSSDSDSSQA---SATLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKNPNK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTT--AKEGKSDSE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09066-1", "uniprot_id": "HME2_MOUSE", "id": "P09066-1", "name": "Homeobox protein engrailed-2", "aln": "-----------------------------------------------------------------------------------------------------------------MEEKDSKPSETAA--EAQRQPEPSSGGGSGGG------------------------SSPSD------------------------------------------------------------------------SDTGRRRALMLPEVLQAPGNHQHPHR------------------ITN----------FFIDNILRPEFG-RRKDAGTCCAGAGGARGG----EGGAGTTEGGGGGAGGAEQLLG--ARESRPNPACAPSAGGTLSAAAGDPAVDGEG--GSKTLSLHGGAKKPGDPGGSLDGVLKARGLGGGDLSVSSDSDSSQA---SATLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKNPNK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTT--AKEGKSDSE--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19622-1", "uniprot_id": "HME2_HUMAN", "id": "P19622-1", "name": "Homeobox protein engrailed-2", "aln": "-----------------------------------------------------------------------------------------------------------------MEENDPKPGEAAAAVEGQRQPESSPGGGSGGGGG----------------------SSPGE------------------------------------------------------------------------ADTGRRRALMLPAVLQAPGNHQHPHR------------------ITN----------FFIDNILRPEFG-RRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGG-AGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEG--GSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQA---GANLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKNPNK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTT--AKEGKSDSE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31533-1", "uniprot_id": "HME2B_DANRE", "id": "P31533-1", "name": "Homeobox protein engrailed-2b", "aln": "-----------------------------------------------------------------------------------------------------------------MEEND----------HSNRDVERQ--------------------------------DSGDE------------------------------------------------------------------------SNR------AILPLLQAPGN-VLPHR------------------ITN----------FYIDNILRPDFG-RRKEG-SRRDEINIV-------------------------------ERENR--CPSAPGSG------QVAP-VSGEG--TSSPRAVNASKKTDIST----DESLKSRAET-GDQCLSSDSDCSQR---CAAQAKQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKTPTK----------------------EDKRPRTAFTAEQLQRLKNEFQNNRYLTEQRRQALAQELGLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHATV--TKDDKSDSD--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09015-1", "uniprot_id": "HME2A_DANRE", "id": "P09015-1", "name": "Homeobox protein engrailed-2a", "aln": "-----------------------------------------------------------------------------------------------------------------MDENE----------QSARDVEQR--------------------------------GASDE------------------------------------------------------------------------SNS------AIRPLLQAPGNLQLPHR------------------ITN----------FFIDNILRPDFG-RKKEANITRYEDNHG-------------------------------ARENH--NPTGPSTG------QVGSTVPAEE--ASTTHTSSGGKEAEIES----EEPLKPRGEN-VDQCLGSESDSSQSN--SNGQTGQGMLWPAWVYCTRYSDRPSSG--PRSRKPKKKAASK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELGLNESQIKIWFQNKRAKIKKASGVKNGLAIHLMAQGLYNHSTT--SKEDKSDSD--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05527-1", "uniprot_id": "HMIN_DROME", "id": "P05527-1", "name": "Homeobox protein invected", "aln": "----MSTLASTRPPPLKLTIPSLEEAEDHAQERRA--------------GGGGQEVGKMHPDCLPLPLVQPGNSPQVREEEEDEQTECEEQLN-------IEDEEVEEEHDLDLEDPASCCSENSVLSVGQEQSEAAQAALSAQAQARQRLLISQIYRPSAFSSTATTVLPPSEGPPFSPEDLLQLPPSTGTFQEEFLRKSQLYAEELMKQQMHLMAAARVNALTAAAAGKQLQMAMAAAAVATVPSGQDALAQLTATALGLGPGGAVHPHQQLLLQRDQVHHHHHMQNHLNNNENLHERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVS-----GSSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICS--NSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGED-------SGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEEELQELQEAASAAAAKEPC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02836-1", "uniprot_id": "HMEN_DROME", "id": "P02836-1", "name": "Segmentation polarity homeobox protein engrailed", "aln": "MALEDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAG-----------GRLPPPAHQQQSTAKPSLAFSISN--------------------ILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLR-RSAANAVIPPPMSSKMSDANPEKSALGSLCKAVS-QIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSG--PRYRRPKQPKDKTN---------------------DEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQIP-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . . : ... . : : : :: . :. : . . . ..: *. . .. : . :... . :***************** ** *:**: .. ::*******:. ** *** **: ******:*** *: **.***:************:**::* ** **::*********:* ::: :. . ", "identical_positions": 82, "similar_positions": 61, "identity": "13.33%" }, { "cls_id": "homologset.agr.HGNC:33433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R952-1", "uniprot_id": "M0R952_RAT", "id": "M0R952-1", "name": "Sulfotransferase", "aln": "MAEKSKFIEYIDDALEKSKETALSQLFLTHQGIPYPVTMCTLETFRALDAFEARSDDILLASYPKCGSNWILHIVSELIFAVSKKKYACPEFP-VLECGDAEKYQRMKRLPSPRILTTHLHCDKLPQSVFKSKAKILVMFRNPKDTAVSFFHFHNDVPDIPSYASWDEFFRQFIKGQVSWGSYFDFAINWNKHIDEENVKFILYEDLKENLVVGIKQISEFLGFSLTDAQIKTISAQSTFQAMRAKSQETHGAIGPFLFRKGEVGDWKSLFNETQNQEMDERFKESLAGISLGDKLKYDSYCLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CC03-1", "uniprot_id": "ST6B1_MOUSE", "id": "P0CC03-1", "name": "Sulfotransferase 6B1", "aln": "MADKSKFIDYIDDALEKSKETTLSQLFLTYQGIPYPVTMCTQETFRALDAFEARSDDVLLASYPKCGSNWILHIVSELIFAVSKKKYACPEFP-VLECGDAEKYQRMKLFPSPRILTTHLHYDKLPQSIFKNKAKILVIFRNPKDTAVSFFHFHNDVPDIPSYASWDEFFRQFIKGQVSWGSYFDFAINWNKHIDDENVKFILYEDLKENLVVGIKQISEFLGFSLTDEQIETISTQSTFLAMRANSQETHGAIGPFLFRKGEVGDWKRLFNETQNQEMDERFKECLAGTSLGDKLKYEAYCLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IMI4-1", "uniprot_id": "ST6B1_HUMAN", "id": "Q6IMI4-1", "name": "Sulfotransferase 6B1", "aln": "MADKSKFIEYIDEALEKSKETALSHLFFTYQGIPYPITMCTSETFQALDTFEARHDDIVLASYPKCGSNWILHIVSELIYAVSKKKYKYPEFP-VLECGDSEKYQRMKGFPSPRILATHLHYDKLPGSIFENKAKILVIFRNPKDTAVSFLHFHNDVPDIPSYGSWDEFFRQFMKGQVSWGRYFDFAINWNKHLDGDNVKFILYEDLKENLAAGIKQIAEFLGFFLTGEQIQTISVQSTFQAMRAKSQDTHGAVGPFLFRKGEVGDWKNLFSEIQNQEMDEKFKECLAGTSLGAKLKYESYCQG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYJ6-1", "uniprot_id": "ST6B1_DANRE", "id": "F1QYJ6-1", "name": "Sulfotransferase 6B1", "aln": "---MSQMKSRMETAAKMKDEDKL----YRRDGILYSTVLSPPETLDKLKDLQAREDDLILVAYPKCGFNWMVAVLRKIINASTGKDEKPPERPPLVEFLPPTVQEEMAQMPPPRLLGTHLHPDNMPATFFTKKPKILVVFRNPKDTVVSYYHFMNKNPVLPNAESWDKFFSDFMTGDVSWGSYFDHALAWEKRIDDPNVMIVMYEDLKQNLPEGVKKISEFFSLPLTDEQVSSIAGQSTFSAMVENSQKSHGNFGSIFFRKGEVGDWKNHFSEAQSKQMDELYHSKLAGTKLAARMNYDLYCQ-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: . :: * : ..* * :** *. .:.. **: *. ::** **::*.:***** **:: :: ::* * : *. ** * ::* . :.* :*.**:* **** *::* :.* .*.****:*******.**: ** *. * :*. ***:** :*:.*:**** ***.*: *:*::* ** :::*****:** *:*:*:**:.: **. *:.:*: **** ** :**.:** .*.::********** *.* *.::*** ::. *** .*. :::*: ** ", "identical_positions": 130, "similar_positions": 95, "identity": "42.76%" }, { "cls_id": "homologset.agr.HGNC:33434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNU0-1", "uniprot_id": "D3ZNU0_RAT", "id": "D3ZNU0-1", "name": "RING finger protein 215", "aln": "MGPADRPALRSPSSPPPPPSPPSPLLLLLPLLPLWLGLMGPGAAADGSEPEARAGRGGARAVRVDVKLPRQDALVLEGVRIGSEASPEPLLGGRLLLMDVVDAEQEIPADGWIAVAYVGKEQVAQFHQENQGSSQKAYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKLLEALLQRTQATAEISSGESLSANIEWKLTLWTTCGLSKDG-YGGWQDLVCLGGAQAQEQKPLQQLWNAILLVVMLLCTGLVVQAQRQASRQSQQEPGGQEDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPG---AETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SPX3-1", "uniprot_id": "RN215_MOUSE", "id": "Q5SPX3-1", "name": "RING finger protein 215", "aln": "MGSADRPALRSPSLPPPPPSPPSPLLLLLPLLPLWLGLMGPGAAADGSEPATGEGRGGARSVRVDVKLPRQDALVLEGVRIGPEDGPEPLLGGRLLLMDVVDAEQEIPVDGWIAVAYVGKEQVAQFHQENQGSSQKAYPKALVQQMRRALFLGASALLLLILNHSVVRELDVSQLLLRPVIVLHYSSNVTKLLEALLQRTQATAEISSGESLSANIEWKLTLWTTCGLSKDG-YGGWQDLVCLGGAQAQEQKPLQQLWNAILLVAMLLCTGLVVQAQRQASRQNQQEPGGQEDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPG---TETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6U7-1", "uniprot_id": "RN215_HUMAN", "id": "Q9Y6U7-1", "name": "RING finger protein 215", "aln": "MGPAARPALRSP--PPPPPPPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAAGAGRGGARAVRVDVRLPRQDALVLEGVRIGSEADPAPLLGGRLLLMDIVDAEQEAPVEGWIAVAYVGKEQAAQFHQENKGSGPQAYPKALVQQMRRALFLGASALLLLILNHNVVRELDISQLLLRPVIVLHYSSNVTKLLDALLQRTQATAEITSGESLSANIEWKLTLWTTCGLSKDG-YGGWQDLVCLGGSRAQEQKPLQQLWNAILLVAMLLCTGLVVQAQRQASRQSQRELGGQVDLFKRRVVRRLASLKTRRCRLSRAAQGLPDPG---AETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNRYSDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCC7-1", "uniprot_id": "A0A8M2BCC7_DANRE", "id": "A0A8M2BCC7-1", "name": "", "aln": "MG--ALACLSAVCWLWFCPLVSSEQVAFVEVFLEDHQHILQGEVVQGSLEND----------PMDNHSKKKHGLKGELILVKDEA-----------LKSNSEINDGKDPDPWIGVVPVQMEEGTVSSNSNQES----FAASMVNKMKRALVLGASALIILALNQNTVREMDLSQVLSKPIIVIQTSENVTKLIGALLRGLRATAKITYKSFLQDSLGATLTLWSSCGRSRGGLYGEWQGVICTGETNSQVQKYLQQLWNTVVLVALVLSTGVIVQARWQY--QDNQFNDDLESNLKQDILKRLSALKTRTYRQPKVRCDPTQTQTMETESCAVCLEQYNNNQCLRVLPCLHEFHRDCVDPWLLLQQTCPLCKRSVLGNFY---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ..* : * .* : :: :: * ..:** :* : ::..* * : : * * . : :: : **.*. * *: : :.*: * :. ::*::*:***.******::* **:..***:*:**:* :*:**:: *.*****: ***: :***:*: . *. .: .****::** *:.* ** **.::* * :.:* ** ******:::**.::*.**::***: * *.:: .. . :*: :::**::**** * .:. . .:. :*:*****: : *:* ****** ************:********* .**** * ", "identical_positions": 139, "similar_positions": 110, "identity": "36.29%" }, { "cls_id": "homologset.agr.HGNC:33437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E1JJS1-1", "uniprot_id": "E1JJS1_DROME", "id": "E1JJS1-1", "name": "glutathione transferase", "aln": "MSVSFLASLLGLSNDEDQLQVAFDEVLKRRVPSRQPTNLRMSAPIRYYYDLMSQPSRALFIIFRLSNMP--FEDCVVALRNGEHLTEDFKKEINRFQRVPCIH-DNGYKLAESVAILRYLSAKGKIPEHLYPKYFVDQSRVDEFLEWQHMSLRLTCAMYFRTVWLEPLL-TGRTPSEAKIETFRMQMERNLDVVEEVWLEGKDFLTGSSLTVADIFAACEIEQTRMADYDVR-IKYPKIRAWLKRVRQSCN-PYYDVAHEFVYKISGTGPQAKL-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7X7-1", "uniprot_id": "A1Z7X7_DROME", "id": "A1Z7X7-1", "name": "", "aln": "----------------------------------------MSKPIRFYYDLLSPIARGLWIGLKFSNSP--VEYCPIALRKFEQLTDEYKK-INRFQKVPAIV-GGDFHLSETIAIIRYLADKGQFDEKLYPKTLENRARVDEFLEWQHLNIRLACSMYFRDAWLFPMNGIAPKPKPEQIQALIEGVENNLGLLERLWLEN-DFLVGKNLTMADILGSSEINQLRLCQYRVDEKKFPKVVKWLERVRVSAN-PYHDEGLTFIDRKSKQSTAAKL-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30713-1", "uniprot_id": "GSTT2_RAT", "id": "P30713-1", "name": "Glutathione S-transferase theta-2", "aln": "------------------------------------------MGLELYLDLLSQPSRAVYIFAKKNGIP--FQLRTVDLLKGQHLSEQFSQ-VNCLKKVPVLK-DGSFVLTESTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTK-VLGPLIGVQVPE-EKVERNRNSMVLALQRLEDKFLRDRAFIAGQQVTLADLMSLEELIQPVALGCNLF-EGRPQLTAWRERVEAFLGAELCQEAHNPIMSVLGQAAKKTLPVPPPEAHASMMLRIARIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61133-1", "uniprot_id": "GSTT2_MOUSE", "id": "Q61133-1", "name": "Glutathione S-transferase theta-2", "aln": "------------------------------------------MGLELYLDLLSQPSRAVYIFAKKNGIP--FQTRTVDILKGQHMSEQFSQ-VNCLNKVPVLK-DGSFVLTESTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTK-VLGPLIGVQVPQ-EKVERNRDRMVLVLQQLEDKFLRDRAFLVGQQVTLADLMSLEELMQPVALGYNLF-EGRPQLTAWRERVEAFLGAELCQEAHSTILSILGQAAKKMLPVPPPEVHASMQLRIARIP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CG30-1", "uniprot_id": "GSTT2_HUMAN", "id": "P0CG30-1", "name": "Glutathione S-transferase theta-2B", "aln": "------------------------------------------MGLELFLDLVSQPSRAVYIFAKKNGIP--LELRTVDLVKGQHKSKEFLQ-INSLGKLPTLK-DGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQ-VLGPLIGVQVPE-EKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELF-EGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZ94-1", "uniprot_id": "E7EZ94_DANRE", "id": "E7EZ94-1", "name": "glutathione transferase", "aln": "------------------------------------------MPLELYLDLHSQPCRSVFIFAKINKIP--FEYKAVDLSAGEQYGDEFGK-VSIIRKVPALK-DGDFLLTESIAILLYLAGKHSTPDHWYPADLQKRAQVDEFLSWQHTNIRSHGSKVFWFKGVLPAVTGAPVPK-EKMDSALEDLNMSLKIFEDKFLQSRPFIIGDKISLADIVAIVEMMQPVATGVDVF-EGRPALSAWRDRVKKEVGVELFDEAHKVIMN-VESLPQTFENKGLPEFFKLKIQKMFN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12390-1", "uniprot_id": "GST2_YEAST", "id": "Q12390-1", "name": "Glutathione S-transferase 2", "aln": "--------------------------MNGRGFLIYNGGEKMKQKMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLA-KNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKG-VIHMMNKRAELELLDPVSVYFHHA-TPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRERPYVAGDSFSMADITVIAGLIFAAIVKLQVP-EECEALRAWYKRMQQRPS----------VKKLLEIRSKSS--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : * . .: : : :: :: . :* : ... ::* ** *: : :. : . : . : * :: *...::**: : : : * *:. . : . ", "identical_positions": 12, "similar_positions": 46, "identity": "4.1%" }, { "cls_id": "homologset.agr.HGNC:3344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIB0-1", "uniprot_id": "D3ZIB0_RAT", "id": "D3ZIB0-1", "name": "", "aln": "MCLAPWLSVASAVCSHFYHRLLRTYFKDRLTRFKFTFYIVQLLSGIGSHPNLKAPKIKLDCEDPLIRAYESFGENMLLLQCRNTASPPKPCDMV---KMSLL-VFLGLLGVSAAMP--MPMPRMPGFSSKSEEMMRYNQFNFMNAPPMMHMGPWQNGLPMPPHMPPQYPPYQMPMWPPPVPNGWQ--QPPMPNFPSKTEQTQETAKPNQTDPQEPQPQKQPLKEPPNEAARAKDEAQPPQPFPPFGNGLYPYQQPPWPIPQTGPPTGFGRPKFSNEEG-NPYYAYFGYHGFGGRP-YYSEEMFE-DYEKPKEKDPPKPEDPPPDDPPPEASTNSTVPDANATQSIPGGGQGGNDSSPVGNTGPGPNAGNNPTVLNGVFPLPKVNVSGQGVPKNQIPWRPSQPNIYENYPYP---NYPSERQWQTTD-TQGPKQNGPGYQNPQIQRGPQWNSFAWEGKQATTHPGNPTYHKPSPPTSRVNYPNYAGNPVNFGRKLPGPKKPFMGANPASNKPFVGANPASNKPFVGTNPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFMGTNPAANKPSIGTNAASNKPFVGTNAGTNKPFMGINVASNKPFMGTNPASNKPFVGTNPASNKPFVRSNHASNKPFVGANAASNKPFVGTNVPSVGPKQVTVSHNMKTQNPKEKSLGQKERTVTPTKDTGNPWRSSKQYGINNPNYNLPHPEGSMVGPNFNSFDQQENTYFSRGDSRKVASPNRQIQSQNLPKGIALEPRRTPFESETKRPELKHSTNMP-VYPKKNPSPTRGHFPAGRNNWNHQKTLPPLKEGHGRKEENLRHPPYGSRGNVFYHEYNNPYPNEKSPYLRGNTWDKRISTPGTMMQPENPQYTMSSLDQKETEQYNEEDPIDPNEDESFPGQSRWGDDELSFKGNPTLRQYEGEQYTSTLAKEYLPYSLSNPPKPSEDFPYSEFYPWNPHETFPIYNPGPTIAPPVDPRSYYVNNAVGQEESTLFPSWTSWDHRNQAERQKESEPYFNRNVWDQSMSLHKSNIQNP----NHPYSTTSPAGFPKDPTWLEGENLNYDLQITSLSQPEREQLAFPDLRPQSYPTGQNEDHLFHQSQRGSCCIGGSTGHKENVLALHDYTSSYGLPPRKTQEISPVHTESSYTKYAKPNVSPASILPNQRNISENKLTAESPNPSPFGDDVPTVRKNTPNSGKNQLETG-IIALSEASSSQPKNTACLKSDLGGDRRDVLKQFFEGTQLGERTAGLTPEQLVIGSPDKGSGPDGTHSEVQGSEGEMQQQRPPTIRKLPCFGSKLAKLHSSSTGPPTNNGGPSLPNGALSTPTESPDTLVGLATREQFKSINVDQLNADGHTTLESFQ-DTSQQDQAHGCLLLQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55196-1", "uniprot_id": "ENAM_MOUSE", "id": "O55196-1", "name": "Enamelin", "aln": "---------------------------------------------------------------------------MLLLQCRNPTSPPKPCGLVPNVKMSLL-VFLGLLGVSAAMPFQMPMPRMPGFSSKSEEMMRYNQFNFMNAPPMMPMGPYGNGMPMPPHMPPQYPPYQMPMWPPPVPNGWQ--QPPMPNFPSKTDQTQETAKPNQTNPQEPQPQKQPLKEPPNEAARAKDDAQPPQPFPPFGNGLYPYPQPPWPIPQRGPPTAFGRPKFSNEEG-NPYYAFFGYHGFGGRP-YYSEEMFE-DYEKPKEKDPPKPEDPPPDDPPPEASTNSTVPDANATQSIP---EGGNDTSPIGNTGPGPNAGNNPTVQNGVFPPPKVNVSGQGVPKSQIPWRPSQPNIYENYPYP---NYPSERQWQTTG-TQGPRQNGPGYRNPQVERGPQWNSFAWEGKQAT-RPGNPTYGKPPSPTSGVN---YAGNPVHFGRNLPGPNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPYVGANPASNKPFIGANPAANKPSIGTNPAANKPSIGTNPAANKPFVRNNVG----------------------ANKPFVGTNPSSNQPFLRSNQASNKPFMRSNQASNKPFVGTNVASVGPKQVTVSHNMKTQNPKEKSLGQKERTVTPTKDASNPWRSAKQYGINNPNYNLPRSEGSMVGPNFNSFDQQENSYFSKGASKRVPSPNIQIQSQNLPKGIALEPRRTPFQSETKKPELKHGTHQP-AYPKKIPSPTRKHFPAERNTWNRQKILPPLKEDYGRQDENLRHPSYGSRGNIFYHEYTNPYHNEKSQYIKSNPWDK--SSPSTMMRPENPQYTMTSLDQKETEQYNEEDPIDPNEDESFPGQSRWGDEEMNFKGNPTVRQYEGEHYASTLAKEYLPYSLSNPPKPSEDFPYSEFYPWNPQETFPIYNPGPTIAPPVDPRSYYVNNAIGQEESTLFPSWTSWDHRNQAERQKESEPYFNRNVWDQSINLHKSNIPN------HPYSTTSPARFPKDPTWFEGENLNYDLQITSLSPPEREQLAFPDFLPQSYPTGQNEAHLFHQSQRGSCCIGGSTGHKDNVLALQDYTSSYGLPPRKNQETSPVHTESSYIKYARPNVSPASILPSQRNISENKLTAESPNPSPFGDGVPTVRKNTPYSGKNQLETG-IVAFSEASSSQPKNTPCLKSDLGGDRRDVLKQFFEGSQLSERTAGLTPEQLVIGIPDKGSGPDSIQSEVQGKEGEMQQQRPPTIMKLPCFGSN-SKFHSSTTGPPINNRRPTLLNGALSTPTESPNTLVGLATREQLKSINVDKLNADEHTTLESFQ-GTSPQD--QGCLLLQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRM1-1", "uniprot_id": "ENAM_HUMAN", "id": "Q9NRM1-1", "name": "Enamelin", "aln": "---------------------------------------------------------------------------MLVLRCRLGTSFPKLDNLVPKGKMKILLVFLGLLGNSVAMP--MHMPRMPGFSSKSEEMMRYNQFNFMNGPHMAHLGPFFG-----NGLPQQFPQYQMPMWPQPPPNTWHPRKSSAPKRHNKTDQTQETQKPNQTQSKKP-PQKRPLKQPSHNQPQPEEEAQPPQAFPPFGNGLFPYQQPPWQIPQRLPPPGYGRPPISNEEGGNPYFGYFGYHGFGGRPPYYSEEMFEQDFEKPKEEDPPKAE-----SPGTEPTANSTVTETNSTQPNPKGSQGGNDTSPTGNSTPGLNTGNNPPAQNGIGPLPAVNASGQGGPGSQIPWRPSQPNIRENHPYPNIRNFPSGRQWYFTGTVMGHRQNRPFYRNQQVQRGPRWNFFAWERKQVA-RPGNPVYHKAYPPTSRGNYPNYAGNPANLRRKPQGPNK-----------------------------------------------------------------------------------------------------------------------------------------HP----------------------------VGTTVAPLGPKPGPVVRNEKIQNPKEKPLGPKEQIIVPTKNPTSPWRNSQQYEVNKSNYKLPHSEGYMPVPNFNSVDQHENSYYPRGDSRKVPNSDGQTQSQNLPKGIVLGSRRMPYESETNQSELKHSSYQPAVYPEEIPSPAKEHFPAGRNTWDHQEISPPFKEDPGRQEEHLPHPSHGSRGSVFYPEYNPYDPRENSPYLRGNTWDERDDSPNTMGQKESPLYPINTPDQKEIVPYNEEDPVDPTGDEVFPGQNRWG-EELSFKGGPTVRHYEGEQYTSNQPKEYLPYSLDNPSKPREDFYYSEFYPWSPDENFPSYNTASTMPPPIESRGYYVNNAAGPEESTLFPSRNSWDHRIQAQGQRERRPYFNRNIWDQATHLQKAPARPPDQKGNQPYYSNTPAGLQKNPIWHEGENLNYGMQITRMNSPEREHSSFPNFIPPSYPSGQKEAHLFHLSQRGSCCAGSSTGPKDNPLALQDYTPSYGLAPGENQDTSPLYTDGSHTKQTRDIISPTSILPGQRNSSEK---RESQNP--FRDDVSTLRRNTPCSIKNQLGQKEIMPFPEASSLQSKNTPCLKNDLGGDGNNILEQVFEDNQLNERTVDLTPEQLVIGTPDEGSNPEGIQSQVQENESERQQQRPSNILHLPCFGSKLAKHHSSTTGTPSSDGRQSPFDGDSITPTENPNTLVELATEEQFKSINVDPLDADEHSPFEFLQRGTNVQDQVQDCLLLQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*:** :* ** .:* **.:* ******* *.*** * ************************.* * :**: . :* *:* ******* * ** *: :.. *: .**:***** *****:.::* ***:***:*.:: .:.:::*****.********:** **** *** **..:*** :***** ***:.:********** ******** *:*****:****.* .* .*.::****.::*:**. * :****:** **: ** *:****.. **: * * **.**** * .*********** **:*** *:** *** *. . * :** * *:* *::***:** **** **.: :****.* *. .*** * *****.:: *: **:* :* ***.*..:*** .* :* * ******.** **: :.***:. .***.::** :*:.**:**:.** * *****.**:**:*:.:* *::*...: * *********.* .** *::***::.****.: * .**:: ***:: **** **.*::*: **:**. **::*:* **.:****.:** **. .*:* *::.*.**: .:*.** : *.* *.:.: **** ******:**. ** ****.*** :*:.***.**:*:****:*:*. .********.**.** *** *******.*.*.** **...*:.**::.*.****** * ******** .***** **: *:* .******:***: *:*: :** :.:** : *:* * *******.:*** :. ****: :**:: * ***:**:* **** ******* *.*** *:* ***:***.****.* :.*: **::*:.*: * :: :**:****.*** **: ** ** * *.*.*:*:*** * **** *:.:.**** *.***.***.***** .::*:*.**..**.***..********* **:**.*:. :*:** .*.* *****..* :******: :* ***:**.* .: : :* ****.*:*** ***.**:****** *:** *:.:* :* .*. ** :.******", "identical_positions": 654, "similar_positions": 289, "identity": "46.65%" }, { "cls_id": "homologset.agr.HGNC:33446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35215-1", "uniprot_id": "DOPD_MOUSE", "id": "O35215-1", "name": "D-dopachrome decarboxylase", "aln": "MPFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLVSSIGVVGTAEQNRTHSASFFKFLTEELSLDQD--------RIVIRFFPLEA-WQIG--------------KKGTVMTFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LB54-1", "uniprot_id": "A0ABK0LB54_RAT", "id": "A0ABK0LB54-1", "name": "D-dopachrome decarboxylase", "aln": "MPFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLISSIGVVGTAEQNRSHSSSFFKFLTEELSLDQDRYVELVRERICDSVLCMRLGWGVGDHLLVPASTPCLSPRKCSVSAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NHG4-1", "uniprot_id": "DDTL_HUMAN", "id": "A6NHG4-1", "name": "Putative D-dopachrome decarboxylase-like protein", "aln": "MPFLELDTNLPANRVPAGLEKRLCAAAASILGKPADRVNVTVRPGLAMALSGSTEPCAQLSISSIGVVGTAEDNRSHSAHFFEFLTKELALGQDR------FPTVLSTSPAAHGGPRCPGEIIEGKKSCLN-EEALFIYFI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**:*****.*:*****:*****:*:**.** ***.**:***::: :. ******:* :**********:**:**: **:***:**:*.** .: . ", "identical_positions": 65, "similar_positions": 27, "identity": "46.1%" }, { "cls_id": "homologset.agr.HGNC:3345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DKY8-1", "uniprot_id": "Q6DKY8_RAT", "id": "Q6DKY8-1", "name": "", "aln": "--MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35709-1", "uniprot_id": "ENC1_MOUSE", "id": "O35709-1", "name": "Ectoderm-neural cortex protein 1", "aln": "--MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWSVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14682-1", "uniprot_id": "ENC1_HUMAN", "id": "O14682-1", "name": "Ectoderm-neural cortex protein 1", "aln": "--MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAINWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEHYDPTINKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKP6-1", "uniprot_id": "F1QKP6_DANRE", "id": "F1QKP6-1", "name": "", "aln": "MKMSVCVHENRKSRASTGSMNIFLFHKSSYADSVLMHLNALRQQRLFTDVLLHAGSRSFPCHRAVLAACSRYFEAMFSGGLRESQDSEVDFRDSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPSNCLGMLLLSDAHQCTQLFQLSWSMCLSNFPAICKTEEFLQLPKDMLVQLLAHEELETEDERLVYESALNWVNYDLERRHCHLPELLRTVRLALLPAIFLMENVSTEELIIAQAKSKELVDEAIRCKLRILQNDGVVNSPCARPRKTSHALFLLGGPTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYVTGGRGSENGVSKDVWVYDTLHEEWSKAAPMLIARFGHGSAELRHCLYVVGGHTAATGCLPASPSVSLKQVEQFDPVANKWSMVAPLREGVSNAAVVSVKLKLFAFGGTSVAHDKLPKVQCYDPSENRWTVPASCPQPWRYTAAAVLGNQIFVMGGDTEFSACSAYKFSSETYQWTKVGDVTAKRMSCQAVASGNKLYVVGGYFGTQRCKTLDCYDPTLDAWNSITTVPYSLIPTAFVSTWKHLPA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.**********:**:**:************ *** ***************.*:***********************:*******:* :*******************************************************:***************:*::*** ****** :* *.*:*****:**:****: ***************:**:.***::*:*:*****:**********:*****: **** * ****:*:*******:********.* *******.******** ****************************************:*******************************:**********:****************************::**. ***:****************.************:*********** .****:***:******************:***************.*******************:**************** **************.************************:", "identical_positions": 522, "similar_positions": 51, "identity": "88.32%" }, { "cls_id": "homologset.agr.HGNC:33451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RAS3-1", "uniprot_id": "M0RAS3_RAT", "id": "M0RAS3-1", "name": "", "aln": "MVKPGRVARPTARSAGLGGSGQPQARQQQQSQGQQRLASRPGQRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKKTLSN----------KKRKKEAQVAFKKTLEKEAKGEEPDITVPKFKQRKGE-------SDVAYIQRMEQEAQHVLFLSKNQATRQPEVQAAPKKEKSERK---KAFQKRRLEKAQKKKEARAVDRLEQ------ELLKDTVKFGEVVLQPPELTVQPRRSTSRD---APGKKSLMLK-MLLGPGGVSP---APATSLARQRILGEERERAVQAYRALKKLHRQEVTPAQPPGSSSQRQPQACL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0K4-1", "uniprot_id": "CC137_MOUSE", "id": "Q8R0K4-1", "name": "Coiled-coil domain-containing protein 137", "aln": "MARPGNIALVTARSAGLRGSGQPQGRRQQQAQGQQRSASLPGQRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKKTLSN----------KKRKKEAQVAFKKTLEKEAKGEEPDIAVPKFKQRKGE-------SDVAYVQRMEQEAQHVLFLSKNQAPRQPEVQAAPKKEKSERK---KAFQKRRLEKAQRKREARAVDRLEQ------ELLKDTVKFGEVVLQPPELTVQPRRSTSRD---APGKKSLMLKKMLLGPGGGSP---APATSLARQRILGEERERAVQAYRALKKLHRQEMTPAQPPGSSFQRQGHACL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PK04-1", "uniprot_id": "CC137_HUMAN", "id": "Q6PK04-1", "name": "Coiled-coil domain-containing protein 137", "aln": "MAGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISN----------KKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGE-------SDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPK-EKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQ------ELLRDTVKFGEVVLQPPELTARPQRSVSKD---QPGRRSQMLR-MLLSPGGVSQ---PLTASLARQRIVEEERERAVQAYRALK--QRQQQLHGERPHLTSRKKPEPQL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VX38-1", "uniprot_id": "Q9VX38_DROME", "id": "Q9VX38-1", "name": "", "aln": "MARKRKIPVRKHHGVRDPLKQLEQKEKKLSKVTNNPPVKKDEQQVSFKFRQFQQLANATKSGKKLRLGEIGREDKPKSSPGSKPGSSSSSKETRNIKQFANETDEDYLRRVNRMTNASVREAHYEAKYGVNVIRNPKTGEITVQKRPKNEIDELLKQKQKEQRLAGKRGRKKVQVVHKP--MDAKTSRELVKRAYKEAQQEVDTEEKQNAGPTEFKQDAVAFGEIVHAPPSLKILPRKAEKSETVPRPGRKANLLLKSMLNPDQGQSNRGPEDDDSSRLKLAAQSKSAFKAPTKAQMKGKRKDLPLATRSMLETERSKMVQLYRQLKNKTTADS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . . . : .:: . :: . : . * : : * :. :** ** *. : ... *: :: *: *: : .. *.: : :..: .::: : * :. ::: :: . *: .*:: * . :. * : .: .* .*.* * *. : .* *: *: :*:* ***:* **.*. *::: . : **::: :* :*.*. . . . :* :: :.:. . :* :*:: . . .:. * ", "identical_positions": 44, "similar_positions": 108, "identity": "13.17%" }, { "cls_id": "homologset.agr.HGNC:33454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQQ3-1", "uniprot_id": "A0A8I6AQQ3_RAT", "id": "A0A8I6AQQ3-1", "name": "", "aln": "MREAEACCTLRKMSAFYQCVRPDPSDLDMISTRVMDIKLREAAEGLGEDSTGKKKSKFKTFKK-LFGKKKRKET-APTGNSAWKQNPAKSEVITIEESGPVYDSEDELEESRGTMGSRALSHDSIFFPESGQDPARPVRVFSQENVCDRIKALQLKIQCNVKLGPPPP-GGLPIKRAEETGMSSEDDGLPRSPPEMSLLHDVGPGPAIKILVSSS----------RPQSPDHMSDASVSSRTLD------GSLAPVVDFSHPPEFSSCLDNSAAKHKLLVKPRNQRSSKLRRLSSRAQSECLSDLSWTLEEEDYEEKSLFHVSMEESPDVRQRDLMPGRRSEFGGPATLLSPGGACARRARLQHSTAVSASMEEGGSLGNEPSSLPATPEVSEPMAVSVPGLESLSLLESSPYHIPRVEIKKEELSTGGLCPLVESTSKEAPCGSGDVETPLSTDIPERDVVPSKEGSAPPEGDQAFPEGDTTLPGGDTLPPEGNTTPPKGVMAPPERDISPSKDNMSPPKRIMAPPERDKSPSEGDVAPPKRIMAPPERDKSPSEGDVAPPKRIMAPPERDKSPSEGDVAPPKRIMAPPERDKSPSEGDVTPPKRIMAPPERDKSPSEGDVAPPKGIMAPPEIDKSPSEGDVAPPK------------------------------------------GIMEPPERDMLLPKGDIPPAKTITDTNLETPSDTERQDQSVQ-EEELTLVVPRPERATGTESSTIPAPSPPAPKSCLKHKTLVPSG--------SAAESPLKEPSLSVQDKAAVPPARHRPTQAATS-GGPERAAPGRKSDRSAEPQRSSVKRFSVTSSRARARASSSRLPEYSAHVPAGGRAPLLRSGLAWRSEAALDDLQVPP-----KPPDRKTTGGDPQNS--GDVGAGQAGPGKSLQDAESCAAT-------LQEPAAGEDQSLFPVKLRSTSLSLKYRDSSAHEAKAIKRYSAEVRLEKGGLALLPKDEQSHVGAAPALRGSRSPNGQGKGKTRSPEQPGTKPPLPRKPLLQSLTLPYPAAGPDTSPGESERLIPVNQPP---EPRKEKSPHQGAEKGQPPAATGPGADGQPTPPWITMARQKRRGAPDLPVNQEEKPGSRLQKTETGKQAKVAERVQESVKQGDFVRSKSFLMTPAKPPVTQRQGSKLSLKEGLQRGISLSHQNLAAQAAATTEKELHQLKRASYAS-SDQPSWMELARKKSQAWSDMPQIIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q3M9-1", "uniprot_id": "E9Q3M9_MOUSE", "id": "E9Q3M9-1", "name": "", "aln": "----------------------------MISTRVMDIKLREAAEGLGEDGAGKKKSKFKTFKK-LFGKKKRKESPSPTGNSAWKQNPAKSEVIAVEESGPVYDSEDELEESRGTMGSRALSHDSIFFPESGQDPARPVRVFSQENVCDRIKALQLKIQCNVKMGPPPP-GGLPIKRAEETGMSSEDDGLPRSPPEMSLLHDVGPGTTIKILVSSS----------RPQSPDHMSDASISSRTLD------GSLAPVVDFSHPPEFSSCLDNSAAKHKLLVKPRNQRSSKLRRLSSRAQSECLSDLSWTLDEEDYEEKPLLHVSMEETPDARQRDLIPGRRPEFGGPATFLSPGGACARRARLQHSMAVSASMEEGGCPRDEPSSLPATPEVTEPMVVSVPSLESPSLPESSPNHILHSKSQKEELSPGGLCPLVESTSEEAPCGSGVAETPLSTDVPERDMGPSKEGSAPPEGDPAFSERHMAFPGGGSIPPEGNTTPHKGVMEPPERDMSPSKDNMAPPKRIIAPPERDMLPSEGDVAPPKRIMAPPERDMSPPEGDVAPPKKIMAPPERDMSPPEGDVAPPKKIMAPPERDMSPPEGDVAPPKKIMAPPERDMSPSEGDVAPPKKIMAPPERDMSPPEGDVAPPKKIMAPPERDLSPSEGDVAPPKRIMAPPERDMSPFKGDMAPPKGIMEPPNRDTSLPKGDTPPPETITDTNLETPSDTERQDQSVQKEEELTLVVVPRPEGVGTESSTAPAPSPPVPKSCLKHKALVTSG--------SPAESPLKEPGPAVQDKAVVPPARPRPTQAATS-GGPERTALGRKNERSAEPQRSSVKRFSVTSSRARARVSGSRLPEYSAHVPAGGRAPLLRSGLAWKSEAALDDLQVLP-----KPQDRKTMGGDPQNS--GDVGAGQAGPGKSPQEAEPCASS-------VQEPANGEDQSPFPVKLRSTSLSLKYRDSSAQEAKAIKRYSAEVRLEKGGLALLPKDEQSHVGAAPALRGSRSPNGQGKGKTRSPEQPGTKPPLPRKPLLPSLTLPYPPTGLDTSPGESERLIPVILPP---EPRKEKLSNQGAEKGQPPAATGPGADGQPTPPWITMARQKRRGAPDLPVNQEEKPGSRILKTETGKQAKVAERAQESVKQGDFVRSKSFLMTPAKPAVTQRQGSKLNLKEGLQRGISLSHQNLA-QAAATTEKELHQLKRASYAS-TDQPSWMELARKKSQAWSDMPQIIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NV74-1", "uniprot_id": "CRCDL_HUMAN", "id": "Q6NV74-1", "name": "CRACD-like protein", "aln": "----------------------------MISTRVMDIKLREAAEGLGEDSTGKKKSKFKTFKK-FFGKKKRKESPSSTGSSTWKQSQTRNEVIAIESGPVGYDSEDELEESRGTLGSRALSHDSIFIPESGQDATRPVRVFSQENVCDRIKALQLKIQCNVKMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVS---------------PDHVSDSTVSARISD------NSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPE-----------------------------------GDTTPP----------------------------------------------------------ETDPAATSEAPSARD----------------GPERS-VPKEAEPTPP-------------------------VLPDEEKGPP----------------------------------------------------------------GPAPEPEREAETEPERGAGTE-------------------PERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRG-AKKFSVSSCRARPRPGVSRPLER-----ASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDS--GDRAASPAGPRKSPQEAAAAPGTR-EPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLER-SLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGERE---PRKEPR---TAEK-RPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQGAKLNFKEGLQRGISLSHQNLA-QSAVMMEKELHQLKRASYAS-TDQPSWMELARKKSQAWSDMPQIIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6Z7-1", "uniprot_id": "A0A8M2B6Z7_DANRE", "id": "A0A8M2B6Z7-1", "name": "", "aln": "-----------------------------------MESIPVDMDKNAEELTGRKKSRFKQLKTRLFGKLKKKES-----EGLIKQSQSASDINAPDSRRGGDDSEDEFTYPQG-LSPRALSHDSIFFTDQTQS-TEPTRVLSQENVHGKIKALQLKLQQQNLHLGPPP-MLIPGKRTEDSGATSEDDGLPCSPPETYLYERVMHGGIYKYPEPR----------------KHLSSLSLAGTG-----------------SEEEEQGDLFQSSSRPLSPVFKPSSQ--SIICSSSSLATPTVGVDFSSPASYTATLDNSAAHHRMSVKPRNQRASTRGNR-----GPAVSISPRKRSESISDLDSILSEKDDDDDDEVDDEIMTSTETVHHLSHSPPTVEIKVET-TIPEAPETPVQIQEEDEEKLSTPHLTPLSAEILKSQESLEPEGKLTMN---------------------------------------------------------------------------------------------------------------------------------------PLYLQPMPFGSGPPSP---------------------------------------------------------------------------------------------------SGLPEVHLIEAESFIQ------------------------KDGMHDIQIVAKESMKEEPSTRFHPVPLPRAK---------------------KPKVEIKSPPSPKASTESVSLQFLLASAKNRSKTNNDATLNEGDLKMKMQTINSNLEVLKD-----------EEKETKPVENLLYRMQKSIEKIEDTKSIRREAPAPPVMSKLAPGTN--GKKVDSPTENVDSEKQEE-----------------PEERRSAFGVHLRTTSLSLKYRSEVSRMKDETKRYSLES-------STVLADSEEHAGKAEVFRGASDSSFRSKAKKQDPQ--SLETPLVAQDYGRSSIQNTTGTCKEAEPDWMSLAREKTRAY---QPLMSRFSTNQSSVQPSPPAQATKPALQPKTQTLTTTVLHPLKTQPIQSSSQQSAHKPAVKPTPAGPKDKPQDNSRNNTTEDDTTKRTATIS----------KMDFNARPVPPNSNTEALTITSDPPPATSSSSSSSPSSPADAV-GAQPSWMELAKRKSLAWSDKKTLE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BEX9-1", "uniprot_id": "A0A8M2BEX9_DANRE", "id": "A0A8M2BEX9-1", "name": "", "aln": "--------------------------------MNVLEASGDPEGEATDDLTGRKKSRLKSLKSRLLVKIKRKED-----DGGLKQSQSESDIAWG---------AEDSDCSKGMLGSRAFSHDSIFQAEHGHSDTEPLRVLSQENIHGNIRALQMKLQQQKMHLGPPP-LLLPSKQREDAGRNSEDDGLPRSPPEVSHSDALYMSISNKYSLPSKNHSTLSLAGTGSEEEEQASSQPLSPRSISPAPLSPQAPGSAVDFSTPPQVVSLLDNSAARHRMSLKPKNQRASAKNKRVSITQDGSRTRSESLNNLDQSVATRQEEEGVALVKEIPRAQSYSSQVLRPGEKLTAMPIKSLPISPLMALQTAEDAQISSEPELASNILSTSPARSPSPKEMPSAEPPVAKPPIPVVPIDRKRKEESETFSSSKLLKSSQSNPVSTVRPAVSTTPELNPVKDQKKTNTVPAQNQMDILRKYSVQSPVNIESSISASPNVICGVSLRPSSFRRYVPSTDDKPESKTLPPVIPVSAVSQDTAQTETIKRQRTVSGSFSVSSDKNQERQRTGSFTGVVGQDGLKKEAIEVNKPTLKFKTDWQVGSQVEKAIKDPCVSLPPSSKKEDKGYSDSVIPPKSTDLSKPMNVEEIQINEKQE----------------------------------------------IKVETTEQGLSEVEAAEEADEDVVEDAMAGKAKESTNAFGVKLRSTSLSLKFRLDKAQSDDKAKRHSFETFPQAPSVASQSD------SASYVEPEAQRTGAIRVHAKLKDPPLQTNSSTNLVQASSSFSREKERPGFLRPTEPPQPSSSDTKIAPSPPKECTDLPPVETPAVSSQETVPTSTPSEVSWMEMAREKTRSLQQLFTSRLPEFPSLQSRPSTSSTTQVQSSQANPKTTPNITSQPTATQPQLKPIDTKQPPCAHPSGRPTQSNTQVTPVQTQTRTTTSQPSASSTTTQPVIDSTKDVQFQSKTQVCNSIVKPTQSSVTSTSNIHASKQPTPIPPIQQSSPFRSASQRPSQAIQQPTPPPGPPHLFSSPKVTSHLGVQQSASTVLKEQALNEEVEPTVISGKADRASVLQGKGSTPEDGRAVWAAGLGNKSSLVQRWENQTTTATKNIDQKSSSESRSAPQSAVSDRPFRPSISKVSGTGPDSSSSSQASVSSVPVRSAEREEKGQQKSPSSSPSSSPLQSARDSGQPSWMELAKRKSLAWSDMSMD--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :*:***::* :*. :: * *:** .. **. : .:: :: .:* :..**:****** .: :. :.* **:****: ..*:***:*:* : *** :* *: *::* .******* **** . : . * .: *. .:: * : . ::.*: .** .* * * : . . . : . .: . .: : :: : .. : . . . . . . . * . . . : . * : . . : . . . . : : :. . * . . . : : : . .: .: .:: : : . : : . . : . . :.: .. . :.. : . : . : . . * . . . *.. . . . : . . ..:.. : . . : . : . . . . .. . . * ********::** **** ", "identical_positions": 81, "similar_positions": 177, "identity": "6.49%" }, { "cls_id": "homologset.agr.HGNC:33455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKX5-1", "uniprot_id": "D3ZKX5_RAT", "id": "D3ZKX5-1", "name": "Solute carrier family 15 member 5", "aln": "-MFVTGFIINDEKAPLPLHGGPERQKTVGHLG---------CFRVGICSLLVELCERFTFFEVVCNMIPFCTRRLGCYNHQAAILNLCFIGASVLTPVFMGWLSDSKYLGRNKLVYIAVFLHFLGTALLSVLAFPSEDFYGGTSPASN-MPMKKRAGLFHVALLTLCLGTGGIRAVVCLPDACGHWEQESKKPMSFCNWASWSMNLNTAVVFLGVSSIQLLGSGAVMILLPSLSVFTASVTLYMTYCDLIYEPENHCSLPTVSRAFARVLKTRCLLYCHLGRAGSSWLARAMAKQGVCHCELQEEETENVFSALLSLFSFQLIYRMCLTQIPSGYYLQTMHSNRTLGGVPLPIALMNAISLLPLLTLGPFMDFFSNCLLPSKRDGPFLSVCIIAGNICAAFSVAVAGFLEIHRK--LAQEQSPSGKLSSVSSMACVYLVPQYVLLGVSEVLVNPAVSTVTRRVVPSTFRRASMTCLTLFHGSAYFAGALLIELVYLISEGNWFPNTLNKGNLESFFFVLASLTLLNILGLWRVLP-RCCNLNHFNAQRIHGNNCEETLLLSEKSLKFYGSTQETSSSIDLRETAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBB2-1", "uniprot_id": "S15A5_MOUSE", "id": "Q8CBB2-1", "name": "Solute carrier family 15 member 5", "aln": "-MPITDFIINDEKTPLVLHGGPEQWKTVGPYG---------CFRVGICLLLVELCERFTFFEVVCNMIPFCTGRLGSYNHQAAMLNLGFIGTSVLTPVFMGWLAD-EYFGRNKLMYIALSLHFLGTALLSMLAFPAENFYRGAYPVFNNTSVEEQAGLFHVALLTLCLGTGGIRAVVCPPDMCGSQERESKKPMPFCNWASWSANLNAAVVFLGISSIQPLGSGALGILLPSLSVFTALVTLYLKHCDLIYRPENRCSLLTIARAFVRALKTRCLPYCHFGRDGSSWLDHAMEKQGGHHSELQEEDTRN-ISALLPLFSFQILYRTCLLQIPSGYYLQTMNSNRNWGGFSLPIALMNAISLLPLLILPPFMDYFSNCLLPSKRDGPFLSACMIAGNICAASSVAMAGFLEIYRK--LAREQSPSGKLFSVSSMACVCLVPQYVLLGVSEVLVNPAVSMVTHRVIPG----ASMAFLTLSHGSACFAGAMLIKLLYLISEGNWFPNTLDKGNLENFFFVLASLMLLNILGLWRASW-RYCNLNHFNAQRIRGNRCEETLLLTEKSLKFYGSTQGASSSIDLWETAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NIM6-1", "uniprot_id": "S15A5_HUMAN", "id": "A6NIM6-1", "name": "Solute carrier family 15 member 5", "aln": "-MSVTGFTITDEK--VHLYHSIEKEKTVRHIGDLCSSHSVKKIQVGICLLLVELCERFTFFEVVCNMIPFCTIKLGYHNCQAAILNLCFIGTSILTPVFVRWLTD-VYLGRNKLVYICLFLHFLGTALLSVVAFPLEDFYLGTYHAVNNIPKTEQHRLFYVALLTICLGIGGVRAIVCPLGAFGLQEYGSQKTMSFFNWFYWLMNLNATIVFLGISYIQHSQAWALVLLIPFMSMLMAVITLHMIYYNLIYQSEKRCSLLTGVGVLVSALKTCHPQYCHLGRDVTSQLDHAKEKNGGCYSELHVEDTTF-FLTLLPLFIFQLLYRMCIMQIPSGYYLQTMNSNLNLDGFLLPIAVMNAISSLPLLILAPFLEYFSTCLFPSKRVGSFLSTCIIAGNLFAALSVMIAGFFEIHRKHFPAVEQPLSGKVLTVSSMPCFYLILQYVLLGVAETLVNPALSVISYRFVPSNVRGTSMNFLTLFNGFGCFTGALLVKLVYLISDGNWFPNTLNKGNLESFFFFLASLTLLNVLGFCSVSQ-RYCNLNHFNAQNIRGSNLEETLLLHEKSLKFYGSIQEFSSSIDLWETAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYQ7-1", "uniprot_id": "A0AC58IYQ7_DANRE", "id": "A0AC58IYQ7-1", "name": "Solute carrier family 15 member 5", "aln": "MLPIDVFDRPEHLLHGICKTSHPGMFNKPHKGR-------KKLQVIICVLFVELFERFTFFGIVCNMILFCTIKLGYSSYQAAMVNTCFVGACILTPVLVGWFAE-TCLGRTTVLCFCALLHFIGTALLPVVAFPFEDFYINTHNIVHQLEPHEQHILFYLALIAVALGIGGIRAILCPMAAYHLQSCDQPKLLSFFNWFYWMVNLNSTVVFLGIAYIQQSVAKNLCFLIPFTSVLLALIALHMVRNKLTFRPKKGSSLLTTLGVFLNSFKMCCLHYRHLSGDVANWLDRAKENNGGCYSETSVENVKI-LVKLFPLFGLQLLYRACITQIPSGYYLQTMHSNLKLNGFLLPVAVMKVISILPVLILAPLLELLNTYYQSPKKKLPSPATFITMGHGCAALSALLAGISEIHRKDYPEVEQTLSGKVLQVSSMTCFQLTPQYILLGVAEAFVTPACSLIAFCLTPSNLRGVSLHFLTLSYGGGCFLGAFLIHLLYFVSGGNFYPNNLSSGNMERFFFILATLMAINTLVFWRISQSRYADLSVELSSGIKDSPLSEKLLQYKTCLRFY-DTMERSDTLTSMETVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :. . . * ::* ** *:*** ****** :***** *** :** . ***::* *:*:.:****:: *::: :**..:: :. ***:*****.::*** *:** .: : :: **::**:::.** **:**::* . . * :.* ** * ***:::****:: ** : : :*:* *:: * ::*:: .* :..:: .** * .: :* * *:. :. * :* ::* :.* *:. : *:.** :*::** *: ***********:** . .*. **:*:*:.** **:* * *::: :.. ..*: . :. : *: ** *. :**: **:** **. ***: ****.*. * **:****:*.:*.** * :: . *. .*: *** * . * **:*:.*:*::* **::**.*..**:* ***.**:* :* * : * .:*. :. *:.. .*.** :..*:** . *.:: **.:", "identical_positions": 200, "similar_positions": 175, "identity": "34.19%" }, { "cls_id": "homologset.agr.HGNC:3346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VGU3-1", "uniprot_id": "Q9VGU3_DROME", "id": "Q9VGU3-1", "name": "", "aln": "-----MLTYVAIALCAVTGASCFILGALVQQHLSFRQIKSVMLTDPYVYQCRQPIYRALSMFGHSSRKSITRTESNQTASIGDESGTSKRYSERQDPGSVSIFEHFLLWGRRKAHNAISKMTLSVGPNGSRHENIEHVADIMKYGFPG-MDEIHVYK--NFVLSYDRRNRIAHWVCEHVKSGCVQERDEKTLNKPNAYITDNTIPTIFSANMRDFKNSDWVGGHLASPQNYKCDALKFLEAYKFTNIVP-INRGLKNHIWYRLESYVRDKAIEFDSVHVYTGPLFMPQ-RITFRNWSVRYHVMGMN-TVAVPTHFFKIIIREDEFN---RDMPIMEGYVVPNAYVDKDMDLRSFLADVRDIEHFAGLKFCDGQQRDQLELPVKPPSMTDFQN---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPZ0-1", "uniprot_id": "Q8IPZ0_DROME", "id": "Q8IPZ0-1", "name": "Endonuclease", "aln": "MDRKWQLLGLGFVLGVTALCASFVGGMYFQHTDARKRLRELIQTDPYAYYLSPKIYEVFTFF-----------ESN-------------------------------------------------------NEDDHRMRQIMKFGFPG-LDDLRLYS--DFVLSYDRRNRVAHWVCEHLQADSIHPNRGRRGRNP--YQPDLSVPSNFRSELSDYRRSGFDRGHLAAAGNHHLQQNHCEDTFFLTNIAPQVGQGFNRSAWNNLEQYVRNLVHRFGSVFVCTGPLYKPN-QRPGGKWAVEYEMIGLN-MVAVPTHFFKVIMVESKLH---LGKPYMEGYVLPNAPIPDGLPLRSFLCDIREIEHYAGLKFFDGLRRSALFGSNYPSESRVFREFS-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O08600-1", "uniprot_id": "NUCG_MOUSE", "id": "O08600-1", "name": "Endonuclease G, mitochondrial", "aln": "-----MRALRAGLTLALGAGLGAAAEHWRRR---EGKAPGLLGRVPLLPVVAA-DLPALPGG-----------------------------------------------------------------------PAGGTGELAKYGLPG-VAQLRSRE--SYVLSYDPRTRGALWVLEQLRPERLRG---DGDRSACDFREDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQRAMDDTFYLSNVAPQVPH-LNQNAWNNLERYSRSLTRTYQNVYVCTGPLFLPR-TEADGKSYVKYQVIGKN-HVAVPTHFFKVLILEAAGG-----QIELRSYVMPNAPVDETIPLERFLVPIESIERASGLLFVPNILARAGNLKAITAGSK-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14249-1", "uniprot_id": "NUCG_HUMAN", "id": "Q14249-1", "name": "Endonuclease G, mitochondrial", "aln": "-----MRALRAGLTLASGAGLGAVVEGWRRRREDARAAPGLLGRLPVLPVAAAAELPPVPGG-----------------------------------------------------------------------PRG-PGELAKYGLPG-LAQLKSRE--SYVLCYDPRTRGALWVVEQLRPERLRG---DGDRRECDFREDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQKAMDDTFYLSNVAPQVPH-LNQNAWNNLEKYSRSLTRSYQNVYVCTGPLFLPR-TEADGKSYVKYQVIGKN-HVAVPTHFFKVLILEAAGG-----QIELRTYVMPNAPVDEAIPLERFLVPIESIERASGLLFVPNILARAGSLKAITAGSK-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08466-1", "uniprot_id": "NUC1_YEAST", "id": "P08466-1", "name": "Mitochondrial nuclease", "aln": "------MCSRILLSGLVGLGAGTGLTYLLLN----KHSPTQIIETPYPPTQKP-NSNIQSHS-----------------------------------------------------------------------FNVDPSGFFKYGFPGPIHDLQNRE--EFISCYNRQTQNPYWVLEHITPESLAAR--NADRKNSFFKEDEVIPEKFRGKLRDYFRSGYDRGHQAPAADAKFSQQAMDDTFYLSNMCPQVGEGFNRDYWAHLEYFCRGLTKKYKSVRIVTGPLYLPKKDPIDNKFRVNYEVIGNPPSIAVPTHFFKLIVAEAPTANPAREDIAVAAFVLPNEPISNETKLTDFEVPIDALERSTGLELLQKVPPSKKKALCKEVNCQIVVRDFSNAAIKQSKDVKLLPPPKKRN----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IPY9-1", "uniprot_id": "Q8IPY9_DROME", "id": "Q8IPY9-1", "name": "", "aln": "----MEAPVKGIIGILATAGSFFALGAYYQHIDVMRKIRRLEQRNPHAYFIRRKLYALLGIFAVRPDNS---------------------------------------------------------EFDVDTDDCHKLGGIMKYGFPS-TNDITINETFDFVTSFDRRNSAILWMCERV----------------------------------DLSNRVVYGDSTSVAPAGAFGQSEAARVFFLSNIRPFLNRGFNLTVWDRLLQYVHEMSQRHGTVYAYTGSIYLPR-ELKSNSWFLEFQSEERT-MVAVPTHFFKILVIDKKFAG--DTIPYAEAYVMPNSPLNNNVELKTLLSDVREIENATGLRFFEGLDRNFVNTQASNSFVPSVNGPLTNPLTLPMTNALDSHSALTSSISPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ95-1", "uniprot_id": "Q9VQ95_DROME", "id": "Q9VQ95-1", "name": "", "aln": "-MSFSESNVHQWALCALAGVTGFVCGAFVQQEASIRQLLQQIRRDPYVYHHRHKLYPMLSTFG---------------------------------------------------------------------TDHEARLWNRPTSWADKFRELVLSPILDLVSATVTLKWDSATTTDLLDLVKYGLPSTENLYVHKDYVVSQDLRTNGVRWICEHFRGDYQR-VSSDGGGYSTMNLRYNDVYVLSCGSMSICKAFKRKIWNDLENYVSSMAKEFGSVYAYTGPIYTPT-CYEIGKWTMKYEVFDWI-PIPVPSHFFKVLIVESGVPG---SQPFMEAFIIENS-RRVGGKLNDHRVKVGEIERYTGLRFNKIMQPVVQFGKDSFTVDTRAWAGRLEEISEPLVTFPPDQKLNLI-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . .. :: . : . . : : : : .: :: : . :: * * : . .* **.:: * . :.:. :.**:****::: : ::: * * : :*. :** : ", "identical_positions": 18, "similar_positions": 48, "identity": "4.3%" }, { "cls_id": "homologset.agr.HGNC:3347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VVU9-1", "uniprot_id": "Q9VVU9_DROME", "id": "Q9VVU9-1", "name": "DNA/RNA non-specific endonuclease domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKCIRFSLLVVGLLAAPAAWARVPCPEVELPPVVEDDGIFERIAVAPPQP--------------------------------VGRAGACSVT----------------------------------IRGG-LPSPEPVYLKT---DSEDFYPFSDVGVMEFESGGSLQLWCPSGFNT------HSENLLT-ASCVSGTTFSVGGSNFEFKDLYCKSWPGFKAVKSGATCNGG-------IVIRVGFEITSSR---FAEQMQICFNEEEEVTRYTRHKLEPGSNYYETGVARITFQTAGFFDGKNVDKLYTQATQLETINNELGGDAEKYFDSSSNVYLARGHLGAKADFDYAPEQRATFLFINAAPQWQTFNAGNWARVEDGLRAWVS--------------KNKLNVNCYTGVYGVTTLPNKDGVETPLYLAKDDNNNGLIPVPKLYFRVVIDP-SSHRGIVFVGVNNPHLTEEQIKRDYVICDDVSDQVTYINWKTTD-----IKAGWSYACEVADFLKTVKHLP--ALTAKGGLLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVV1-1", "uniprot_id": "Q9VVV1_DROME", "id": "Q9VVV1-1", "name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKCL--VLIAFSGLFLASAQARI-LPAEDLP------WELPEVPVAVNEI--------------------------------EPRAAGCSIK----------------------------------IRSSELKDPQPLLIKS---DTSEIVGFSDTGYVDVDKDKTIEFHCTSSLASP-----LSGKSVT-AKCVGGTTFKIDDKEHDLSAIKCTSWPVFVGKKSGSSCNGGT------TLIKVGFELSGSR---FATQYEVCFNEDEEVTRYVYHRLEPGNNYYATGVDRITFGAGGYFAGKNVDKLYTQAVQKETIDKELDMDSSRFFDSAKNIFLARGHMGAKADFVFAPEQRATFLFINAAPQWQTFNAGNWARVEDGVRAWVA--------------KENKHVECWTGVWGVTTLPNKNGEQRQLYLSHDNNGNGLIPVPKLYFRVVIEP-STKKGIVLIGVNNPHLSLEEIKRDYILCTDVSDRINWISWKKTD-----ITAGYSYACEVPEFRKKVTHLP--EFSVSG-LLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU22-1", "uniprot_id": "Q9VU22_DROME", "id": "Q9VU22-1", "name": "DNA/RNA non-specific endonuclease domain-containing protein", "aln": "MWSNRCSIFILALLVASGAVKVSGRLPRILPESLAEGDEGVTVRGDCEFKVNGDLNDPAPLFSRHNSYEIIVPDPTDTVRLVNGELLDMFCPGVGFAAPFVNRWQVTATCLQNKYFLVDDLIYPFANFSCTAWPIFTALRSGKDCNGGTDLVQVGFEVEDGGFLQSYELCHDAEAEATRYVHHVLYPSSYDYQHGVARPNFLELDFYGGRDVNTKYTQVQQNITISNILGLDASPYFNFSDDRILSRGHMIAKTDQIFGAAQHTTFLFINVAPQWQTFNGGNWEKVETSVRKFVADRNLTTDCYTGTWGVSTLPDVDGIERELYLDFDENNNGLIPVPKIYFRVVIDRVTREGIVLIGINNPYLTLEQIQKDYILCQDIGHQLSWLTWYKEDLHEGYSYACSVEDFIEVVKDLPLEDLHTNGILGLDDVTTVEPSTTESSTTTEEPSSTTSTEIPSTTDTTPSSTSVSSTTEEPSSSTASPTTELPTSTVISTTEPPTSTVTSTTKPPTSTVASTTEQPTSTVTSTTEPPTSTVTPTTEPPTSTVTSTTEPSSSTTLEPTSTTSSSTTSQPTLSTEESTSTSPTSTSTSSPPVTTANPIANPCRFSTNGDLKDPAPLLTPQGALSWLLPDESGLYTVEEGSSIDLHCTGALVSPFNRYTALSARCVGDQLYEAEGQLVNIRGFVCQSWPTYAAVRSGQSCAGGTDVVHIGFDVAAGFLSHVELCYDQQEQISRYARYELTPANVAYQKGVAQPGYLRGDFYSGEDVNVLYDQSHQLDAFSTALGLDASQYFDSTKDLYLTRGQLAARLDFVHSSAQRATHFYVNAVPQWRSINIGNWLAVESSLKQFVADEALNVSVHAGSYDISTLPNSQGVQTPLYLNAETKQLPVAKILYRIVIDQESRKGVVLIVVNNPHITLTETLEDYVICEDVGAQIDWLDWDKANLQKGYSYACSVEDFIEVVKDLPTDQLQTTGILGLTDQILDNEVCSFKVNGDLKDPAPLFVVRSELGHARYLEPNQEGVVQLKHGEALEFHCINSFSGP-----FSGYTFVNSTCWQQQSILAMGSLYQLQDFVCTSWPTYTARRSGRPCNGGT------DLLEVGFQLSSSSSDDFLQTYDVCHDELSEVTRYVHHVLYPGSDQYQRSVSRPSFIPGDFYGGKDVNTLYTQVQQNITVSEILGMDASPYFNTTGNVYLARGHLSAKTDFVFGAAQKASFFFVNAAPQWQTFNGGNWERIEDSVRKFVA--------------DENITVDCYTGTWGVSTLPDVNGIGRELYLDFDENNNGLIPVPKLYFRVIIDR-ESRNGIVLLGVNNPHATIEQIEEEYIICQDIGAQLSWVSWTKED-----LKKGYSYACTVEDFTAVVKDLPLQDLFVDGVLGV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU24-1", "uniprot_id": "Q9VU24_DROME", "id": "Q9VU24-1", "name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMLQFIGLILAVVILREIRAREAIATIPDVGQIIKDLDGLHIDGEMFHQ---------------------------------GSPCRVDVQN----------------------------------DLPRLDKVQPLYLRP---GTDLYWLPNAYGHLEVQRGASIELHCSHSFAPANGESLDAKLRSIRVKCVQDTTFEWMGAKIHFSDFVCNHSMPYTVERLDRSCGSDTPSPSTSYLYRVGYDTGDGR---FVATMELCHDPNQLRTHYAHHQLTPANVHFQKKLKRPRFSTAGHFTGFDMARIYSPKSQEK-------LMVPGLIDVKSGLFLARGHLTAKADLIYASQQKSSFNYMNVAPQWQSFNGGQWSKLEESTRQYVA--------------RSGITATVYTGIYGEMKVAG----SKVLHMTTNANNIGVVAVPQLFYRVLIDEGHPTRGIALVGVNNPHATLAQIHESYIICDPVEESVQWLSWLHKSNAKGNLKNGYLYACSVANLARAVGHLPRPLLEVDELLT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAU2-1", "uniprot_id": "Q9VAU2_DROME", "id": "Q9VAU2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDLKYMLTILSLYFFVGSVQANCLIDLAHL------------------------------------------------------------------------------------------------------------------NANYVYLSQNNGVYDIQRSDIVEIHQTLYLLCN------GGLHRTTFLCRYDSVFSP-----ALSSAACAPPDPVVVKVPDTSCSIPS------ATFAVGFSFNGR----FMELYRNCFDGYSLAFQHSIYKAYRYVNTVPR--PNPTWQSDQLSGG--FDNAYEGRATQACLLTNLG-------AVQPQCKFDRGHMTPASAFISTELKKSTFRYLNAIPQYRGVNRGKWKAVETWVNNMVRGLYDNPIINNVQIPRTYDVLKVCIGALGVHRLRHN---TNNNMIPIYLLDNNKIPVPEWMYKIVSHLS-GDKWVMLTYND---VSLPNQQALNQICH-VIPCHPGLNLNTKD-------VGHTVCCDPYRFITINAPHLTGVC--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KRX0-1", "uniprot_id": "Q7KRX0_DROME", "id": "Q7KRX0-1", "name": "Endonuclease", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMHELRYLIITLSLFLTVGNVKSFCQITQAET------------------------------------------------------------------------------------------------------------------WTDRLFVHIVNNRYELLLTDQLQPNQQISLLCD------GNAQVFTSTCRNNGQFSP-----PLPRTNCSKAIPPSV-VPTSSNICPH------TMYLVGFKYGNT----FMELYRSCYDARTMKAYFSINTVYPTNLKSDR--PPTVFDKDGIITP--ADEATFQMNSIYNRFEYLFGSGQTYVPSSRSLSFDRGHLTPVADYSFPKILRQTNKYLNVVPQYYNINRSNWKIVENWVRGQK------------------DVLNVCTGALGVLDLLNR---SQK-SVSIYLAPN-KNPVPRWTYKIIRSLTTGIKYVILTSNN---GWETQQPNPASVCK-VTACPR--TLNPTG-------TGYTFCCDPIDFIRRNVPNLAGVCWDNTENV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZTW9-1", "uniprot_id": "D3ZTW9_RAT", "id": "D3ZTW9-1", "name": "Nuclease EXOG, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAKGFASRLRDSRRFLNGFLAGAVVGAAGAG-----------------------------------------------------------------------------------------------------------------LTALQFLQRRDAGSARPARQPHESVEKVVLEQFG-----FPLTGTETRRYTN---------HALSYDQAKRVPRWVLEHISKDKIIG-------DADRKHCKFKPDPT--VPSAFSALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQNFE-NNSGYWNRIEMYCR-------ELTERFEDVWIVSGPLTLPHTR-NDGTKTVSYQVIGED-NVAVPSHLYKVILARRSPE-----------------------STEPLALGAFVVPNKAIGFQSQLSEFQVSLHDLEKMSGLVFFPHLDRTRDIRNICSVDTCKLLGFQEFTLYLSTRKIDGARSVARLEKVLEALKSSGVEPDDYFLSRYGKKLEELKAKEQKDAQLEKQS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C163-1", "uniprot_id": "EXOG_MOUSE", "id": "Q8C163-1", "name": "Nuclease EXOG, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAKSFASRLRDSRRFLNGFLAGAVVGAAGAG-----------------------------------------------------------------------------------------------------------------LTALQFFRRPDAESAKLARQPHESAEEAVLEQFG-----FPLAGTETRRYTN---------HALSYDQAKRVPRWVLEHISKDKIIG-------DADRKHCKFKPDPS--VPSAFSALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQNFD-NNSGYWNRIEMYCR-------ELTERFEDVWIVSGPLTLPHTR-NDGTKTVSYQVIGED-NVAVPSHLYKVILARRSPE-----------------------STEPLALGAFVVPNKAIGFQSQLSEFQVSLHDLEKMSGLVFFPRLDRSRDIRNICSVDTCKLLGFQEFTLYLSTRKIDGARSVARLEKVLEALKSSGVEPDDYFLSRYEKKLEELKAKEQKDAQLEKQS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2C4-1", "uniprot_id": "EXOG_HUMAN", "id": "Q9Y2C4-1", "name": "Nuclease EXOG, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAG-----------------------------------------------------------------------------------------------------------------LAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFG-----FPLTGTEARCYTN---------HALSYDQAKRVPRWVLEHISKSKIMG-------DADRKHCKFKPDPN--IPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFD-NNSGYWNRIEMYCR-------ELTERFEDVWVVSGPLTLPQTR-GDGKKIVSYQVIGED-NVAVPSHLYKVILARRSSV-----------------------STEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08466-1", "uniprot_id": "NUC1_YEAST", "id": "P08466-1", "name": "Mitochondrial nuclease", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCSRILLSGLVG-LGAGTGLTYLLLNKHSPTQ-----------------------------------------------------------------------------------------------------------------IIETPYPPTQKPNSNIQSHSFN--VDPSGFFKYG-----FPGPIHDLQNREE---------FISCYNRQTQNPYWVLEHITPESLAAR------NADRKNSFFKEDEV--IPEKFRGKLRDYFRSGYDRGHQAPAADAKFSQQAMDDTFYLSNMCPQVGEGFNRDYWAHLEYFCR-------GLTKKYKSVRIVTGPLYLPKKDPIDNKFRVNYEVIGNPPSIAVPTHFFKLIVAEAPTANP---------------------AREDIAVAAFVLPNEPISNETKLTDFEVPIDALERSTGLELLQKVPPSK------KKALCKEVNCQIVVRDFSNAAIKQSKDVKLLPPPKKRN--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VAU3-1", "uniprot_id": "Q9VAU3_DROME", "id": "Q9VAU3-1", "name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRILLLLLAFCALAHGQCRFTRAQVQGTN-------------------------------------------------------------------------------------------------------------------RIFMVRGQNRQLSLKRTASSAVGETLQMWCNP-----RDIVATTCQAGRVPAFQP-----PLPMTCRAAPAAITTPVQDRRCPAT--------MYRVGYNVGNNQ---FLELYRACFDTRAVRAIFVEHRVYGKPFYITR--PCVQFSSDGVISG--ADEASYTVRNIHGTFRRLFGNNQNYIPNNRDVIINRGHLAASADFFFGDQLCATFKYVNAVPQFKSINDGNWETIERFVRNSVTG---------------NNFVNVRTGARGVLSLPSG------NRPKNVFLSGNRNPVPQWMYKIVRNANNQPIVAFLTLNN---IYARQRPAAPNFCQPVNCPVALVNTAQAG---------FSFCCNPATFRP------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . * : . :. . . : . : . ", "identical_positions": 1, "similar_positions": 14, "identity": "0.07%" }, { "cls_id": "homologset.agr.HGNC:33480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P82712-1", "uniprot_id": "CCD1P_DROME", "id": "P82712-1", "name": "Probable cytochrome P450 12d1 proximal, mitochondrial", "aln": "-------------MNTLSSARSVA--------------------------------------------------IYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMR---AFMP-GGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDP-KTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKN--RDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAG---EKINSNSMLERLMEIDP--KVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMK-EATYYPRPDEFLPERWLR---DPETGKKM----QVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMF-VMEPAITFPFKFTDIEQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KR10-1", "uniprot_id": "CCD1D_DROME", "id": "Q7KR10-1", "name": "Probable cytochrome P450 12d1 distal, mitochondrial", "aln": "-------------MNTLSSARSVA--------------------------------------------------IYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMR---AFMP-GGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDP-KTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKN--RDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAG---EKINSNSMLERLMEIDP--KVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMK-EATYYPRPDEFLPERWLR---DPETGKKM----QVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMF-LMEPAITFPFKFTDIEQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGZ0-1", "uniprot_id": "C12E1_DROME", "id": "Q9VGZ0-1", "name": "Probable cytochrome P450 12e1, mitochondrial", "aln": "---------------MLSTQWNAN--------------------------------------------------KQIS--RQIYQLCRGLAQKATAVNLEEAKPYADIPGPSKLQLIR---AFLP-GGLYKNLPVHEMFLDMNRQYGSIFRMPSVAG-TDLVLTMNPQDYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIRIIRDP-VTQEMPDDFAVDIRHLVIESICSVALNTHLGLLGEQ--RNNKDIQKLVLALQDVVELGFQLDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGTLNEIGLETSLLEKLARFDR--QTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVREFIPERWLR---DESNSHLVG--ETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNFKIGFDYPIENAFKAQF-FVQPNIPFKFKFIERNE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VE01-1", "uniprot_id": "C12A5_DROME", "id": "Q9VE01-1", "name": "Probable cytochrome P450 12a5, mitochondrial", "aln": "--------MLKGRIALNILQSQKP--------------------------------------------------IVFSASQQRWQTNVPTAEIRNDPEWLQAKPFEEIPKANILSLFA---KSALPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKEIRDA-STQEVPGNFLETINRWTLESVSVVALDKQLGLLRES--GKNSEATKLFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEG-VVRPEHEQSVLEKLLKVDK--KVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLY-SEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAFRSAL-INLPNIPLKFKFTDVPN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VE00-1", "uniprot_id": "C12A4_DROME", "id": "Q9VE00-1", "name": "Probable cytochrome P450 12a4, mitochondrial", "aln": "--------MLKVRSALSLIQSQKA--------------------------------------------------TLSLATQKRWQTNVATAEAREDSEWLQAKPFEQIPRLNMWALSM---KMSMPGGKYKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDP-DTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNS--NKESEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEG-VVRPENEQSVLEKLLKVDR--KVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALT-RDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSAL-INLPNIPLKFKFIDLPN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVR9-1", "uniprot_id": "C12C1_DROME", "id": "Q9VVR9-1", "name": "Probable cytochrome P450 12c1, mitochondrial", "aln": "--------MLR----LTVKHGLRA--------------------------------------------------NSQLAATR--NPDASSYVQQLESEWEGAKPFTELPGPTRWQLFR---GFQK-GGEYHQLGMDDVMRLYKKQFGDICLIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFGN-GAEWGKNRSAVNPVLMQHRNVAIYLKPMQRVNRQFVNRIREIRDK-ESQEVPGDFMNTINHLTFESVATVALDRELGLLREA--NPPPEASKLFKNIEVLMDSFFDLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQAIERIDRKSSQG-DS--NDHKSVLEQLLQIDR--KLAVVMAMDMLMGGVDTTSTAISGILLNLAKNPEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRIPKGTKLLMTNSFLLK-DDRLYPRAKEFIPERWLRRKDDDKSDVLMN--KDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIEYNYSTEKPYKCRF-LYKPNIPLKFKFTDLKY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V8M2-1", "uniprot_id": "C12B2_DROME", "id": "Q9V8M2-1", "name": "Probable cytochrome P450 12b2, mitochondrial", "aln": "--------MWKYSNKIIYRNVSGNQLWFNR--------------------------------------------NSSVGGTLSQQTQLELADSRIDEKWQQARSFGEIPGPSLLRMLS---FFMP-GGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNP-ETHTLTTDFHNQLKMWAFESISFVALNTRMGLLSD---NPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIETAMRGFGKNDDG-------KTKCVLEQLLEHNK--KVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSN-DDKYFAQSSEFIPERWLKSDLAPDIQACPAA-RTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTI-ILSPCGDIRFKLEPVGDLM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V5L3-1", "uniprot_id": "C49A1_DROME", "id": "Q9V5L3-1", "name": "Probable cytochrome P450 49a1", "aln": "-----MSGLRKTSIALMRRSTSSTTILPHSGGVGGAVSPPSSGVGVATEIEKSIAMQRLRTGESSNPKKLNVSQQPVTSVATTRTTASSLPAETTSSPAAAVRPYSEVPGPYPLPLIGNSWRFAPLIGTYKISDLDKVMNELHVNYGKMAKVGGLIGHPDLLFVFDGDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHILLQPQTAKKYIPPLNDIASEFMGRIELMRD--EKDELPANFLHELYKWALESVGRVSLDTRLGCLSP---EGSEEAQQIIEAINTFFWAVPELELRMPLWRIYPTKAYRSFVKALDQFTAICMKNIGKTMDKADADEARG-LSKSEADISIVERIVRKTGNRKLAAILALDLFLVGVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRACVKETLRMRPVVIANGRSLQSDAVINGYHVPKGTHVIFPHLVVSN-DPAYFPEPKRFLPERWLKQSTDAAGCPHAN--QKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKVSYNS-GEFVYRVNS-TYIPQSPLNFKLTLRDE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V6D6-1", "uniprot_id": "CP301_DROME", "id": "Q9V6D6-1", "name": "Probable cytochrome P450 301a1, mitochondrial", "aln": "--------MNNLSLKAWRSTVSCGPNLRQC-------VPRISGAGS----------RRAQCRESSTG--------VATCPHLADSEEASAPRIHSTSEWQNALPYNQIPGPKPIPILGNTWRLMPIIGQYTISDVAKISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLLD--ENQELPEDFDNEIHKWSLECIGRVALDTRLGCLESNL-KPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPTPLWTRYVKNMNFFVGVCMKYIQSATERLKTQDP----SLRAGEPSLVEKVILSQKDEKIATIMALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGN-MEEYVTDAATFRPERWLKP--QHGGTP-----GKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNH-KPLDYAVTF-MYAPDGPLRFKMTRV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8WGA0-1", "uniprot_id": "C27C1_DANRE", "id": "A8WGA0-1", "name": "Cytochrome P450 27C1", "aln": "--MALQSTILHMARKNLLQESCRQLLIQTHGL---------------------------------HKSVASGSLEIAAHSQADLKEESAVSPAEEVQKAARVKSLKEMPGPSTVANLL---EFFYRDGFSR---IHEIQMEHAKKYGKIFKSR--FGPQFVVSIADRDMVAQVLRSESATPQRGNMESWKEYR-----DLRGRSTGLISAEGDEWLKMRSVLRQLIMRPRDVAVFSSDVNDVVADLVKRVKTLRSQQDDSQTVLNINDLFFKYAMEGVATILYETRLGCLENEIPKMSQEYITALHLMFSSFKTTMYAGAIPKWLRPIIPKPWEEFCSSWDGLFKFSQIHVDKRLSEIKKQMEKS---EEIKGGLLTHMLVTREMNLEEIYANMTEMLLAGVDTTSFTLSWSTYLLARHPTIQQQIFEEVDRVLGGR--VPTGEDVPYLPLIRGLVKETLRLFPVLPGNGRVTHDDLIVGGYLIPKGTQLALCHYSTSM-DEENFPRPEEFRPDRWIRK----------DASDRVDNFGSIPFGYGIRSCIGRRIAELEMHLALTQLLQNFHIEVSPQTTEVHAKTHGLLCPGASINLRFTDRK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4G0S4-2", "uniprot_id": "C27C1_HUMAN", "id": "Q4G0S4-2", "name": "Cytochrome P450 27C1", "aln": "MQTSAMALLARILRAGLRPAPERGGLLGGGAP---------------------------------RRPQPAG-ARLPAGARAEDKGAGRPGSPPGGGRAEGPRSLAAMPGPRTLANLA---EFFCRDGFSR---IHEIQQKHTREYGKIFKSH--FGPQFVVSIADRDMVAQVLRAEGAAPQRANMESWREYR-----DLRGRATGLISAEGEQWLKMRSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGVATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFCRSWDGLFKFSQIHVDNKLRDIQYQMDRG---RRVSGGLLTYLFLSQALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERH-VPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSY-QDENFPRAKEFRPERWLRK----------GDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQTNAVHAKTHGLLTPGGPIHVRFVNRK---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* * : . :* : * : : . : * * * . .: :. *: . * * :. .:: : : ::: . :. : :* : : : .:* : : . : : : . : :::: * *. *: * * : *: : . : ::. :** * . .. * * :: ** : *. : . * *:**:: * :*:*.* * * *:*..:: :. .:.: :.: . * : .:: ", "identical_positions": 39, "similar_positions": 94, "identity": "6.43%" }, { "cls_id": "homologset.agr.HGNC:33482", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWR7-1", "uniprot_id": "A0A1B0GWR7_RAT", "id": "A0A1B0GWR7-1", "name": "", "aln": "--------MPS-LVVSG-IMERNGGFG-ELG--CFGGS---AKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAAPAAPSAAPAAQTPQPPTAPKGANDAKLCALYKEAELRLKG-SSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGV-------------------APALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNSDGDFLAG-SPDAALDSRYSDAWRVHAPGCK------------PLS-TFRQNSLGCIGECGVDSAFEAPRLGEQGGDFGYGGYLFPGYGV----------------------------------GKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSS---AKARAGP-----------------PGAHRSPATSAGPEQLTGLPRRPPGEPLQGFSKLGAGGLRSPGGG--------------------------------RDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UYU0-1", "uniprot_id": "G3UYU0_MOUSE", "id": "G3UYU0-1", "name": "", "aln": "--------MPS-LVVSG-IMERNGGFG-ELG--CFGGS---AKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAAPAAPSAAPAAQTPQPPTAPKGANDAKLCALYKEAELRLKG-SSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGV-------------------APALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNSDGDFLAG-SPDAALDSRYSDAWRVHAPGCK------------PLS-TFRQNSLGCIGECGVDSAFEAPRLSEQGGDFGYSGYLFPGYGV----------------------------------GKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSS---AKARAGP-----------------PGAHRSPATSAGPEQLTGLPRRPPGEPLQGFSKLGTGGLRSPGSG--------------------------------RDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L020-1", "uniprot_id": "MEX3A_HUMAN", "id": "A1L020-1", "name": "RNA-binding protein MEX3A", "aln": "--------MPS-LVVSG-IMERNGGFG-ELG--CFGGS---AKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPPTAPKGASDAKLCALYKEAELRLKG-SSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGV-------------------APALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLAG-SPDAAIDSRYSDAWRVHQPGCK------------PLS-TFRQNSLGCIGECGVDSGFEAPRLGEQGGDFGYGGYLFPGYGV----------------------------------GKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSSS--AKARAGP-----------------PGAHRSPATSAGP-ELAGLPRRPPGEPLQGFSKLGGGGLRSPGGG--------------------------------RDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXM9-1", "uniprot_id": "E7EXM9_DANRE", "id": "E7EXM9-1", "name": "", "aln": "--------MPSLLVLAG-IMEKNGGYGGDLAGSGFGSEGLLVPPEEEEDDSRALRVALGQLSLLGLGEG---EDGAPAGGGGGGGGVQDRS-----------------NNNHHNHIQAEPGMLQGKN--KLCALYESSPTETKGRGCNITECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFLITGRKEDVALARREIISAAEHFSMLRASRNKFSGSP---------------------PAPLPGQTTIQVRVPYRVVGLVVGPKGSTIKRIQQQTCTYIVTPSRDRDPVFEITGSPGNAERAREEIEAHIAFRTGGLHDHNNENDCLGPESGNGGLESRLQQVWGLQGAPRK------------PLASSYRQN---------FSDTVVGSSSGGGGGIYSKGDFNNHGSSG----------------------------------DKPSSYFGSEGTQS--WGDPDYPKQVAYYAQQRSKSFGGLPLPLTRLSPGLPE-------------PCGTGNSNAVGSPHAQARRAHSEPTAATGAFTGRLPVPDSPPAMS--------------------------------RDCMTCFESKVTAALVPCGHNLFCMECAIRICELNHPECPVCHTLVTQAIRIFS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4F3-1", "uniprot_id": "Q9V4F3_DROME", "id": "Q9V4F3-1", "name": "RING-type domain-containing protein", "aln": "MAAQVTPKISTCINSKGSIQKKNQAQHHDMS----EQSKVNESTLPLSDDPRTLQLAL-ELSLVGFNDN---QNCYAQPAQPLPMPLSARSDFEIG------------TINSTLPIPSAPNCLLLPN-----AGAVSSEDRSKK-SQNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVNKAKREILSAADHFSLIRASRKPVSDSQNNGMVGSTTSSGGGAVPRMSGPPCMPGQVTIQVRVPYRVVGLVVGPKGATIKHIQQETQTYIVTPSREKEPIFEVTGLPDNVDTARKQIEAHIALRTGSGSGSGDAITMQSSDSVDTKEYASLPSLTQILNDDLNSEILSSIYKNSVPSTQEYANNSMKTVVN--VSNSVKLVQGHHTGNCFQKSEFAEMEMTANITAADILDKRLPGNEVSVPLAKANVANIVFRTTSSKTLSFCPPTSTSASFHSNCNANILTRSCSSASSTTSTKSTNNSANTPPEILNIWKSISDSIDVDEGIGDSPSIWNQPANIIPTAHCSPTISISPTDSLLGMGEHSANQQNLNHAKEPIMPNLPQKIKGIQVQSNADNFLTHRECFVCNENTVTTALVPCGHNMFCMECANHICLSMDAVCPVCNSIVYHAMRILG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: : * * ::* . ::. . :* *:*::** :*.*:*:.: . . : . * . * .: . * . * *******:*************************************::***:*** *:***:***:***::****: . : .. :***.**:****************:***:***:* ***:****:::*:**:** *.*.: **::**:***.*** .. . * : : . : : * : : :* ... . *. : . : .. : : . : . .. : .. *.: . : * .. * .: * . .. *:*:.* *. **:********:****** :** .. ****: . :*:**:.", "identical_positions": 168, "similar_positions": 120, "identity": "25.61%" }, { "cls_id": "homologset.agr.HGNC:33488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKN0-1", "uniprot_id": "D3ZKN0_RAT", "id": "D3ZKN0-1", "name": "", "aln": "----------RP---TGPALVAP----AYLQLWLPGAALEFSQR-------LGPPNAEPTMRRHEEKDAELDRRIVALRKKNQALLRRYQEIEEDRRQAEQGGMAVTTPGFLQPDSLTVTISQVPGEKRVVSRNWARAPLSPGVTATQTDG-DAADSLGTFSMGDRVELAVTMENKAKAKRIVSEKPMSQARSPRAKGTSGGGRGQSSPLQTTFSPDSAGKGALEPRSPGLVPGPPSQQPLGMPPEATWDYTQWKQEREQIDLARLARHRNPQGDWSRPWDLDKAKPMPQNCNKPRDKDLA-MGSRKGPRTHQKPQHPPSFLDGKCRGGQSGRPSVTSTIGSKPQGKERLTGRARRCTIL----LLQ---GSQSTMKTPSAEEECIQKRTEREPDRQETKSATSPILASPEGLREELGTSTASLAPDSPQHSDLAPLDLSVGGASSPRPGESTHIPSPKAGAQESPESWPNGSEQQTLEGSDHQPGLEVHSCTESLREAETPEPKEDRVARAGAQQNLTPRSRPPRGIGPRARGMS-KRSRAGGPGPAGRC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KGF9-1", "uniprot_id": "CCD9B_MOUSE", "id": "A3KGF9-1", "name": "Coiled-coil domain-containing protein 9B", "aln": "MISCAEQRSRSR---QGEADRAGSGGSSFPPALAPGSCFEILSAPGISMHLAGPHKAESTMRRHEEKDAELDRRIVALRKKNQALLRRYQEIEEDRRQAEQGGMAVTTPGLLQPDSLTVTISQVPGEKRVVSRNWARAPLSPGVTTTLTDDEDAADAPGTFSMGHRVELAVTMENKAKAKRIVSEKPTTQARSPRAKGTSGGGRSWRAPLQMTSSSDSAGKGVLEPRSPGVVSSPPPQQSLGLSPEASWDYTQWKQEREQIDLARLARHRNPQGDWSRPWDLDKAKSMPQNCHKPRDRDLA-MGSRKGPRTHQKPQHPPSSLDGKCRGGQSGRPSMTSTIGSNAQGKERLTGRARRYDMKED-EMLQSQEGSQSSTKTPSAEEEFVQKRNEREPDRQETVPATSPIPASPEGLKGESGTSTASLAPDSPQHSDLAPLDLSVGGASSRKPGKSTCILGPKAGAQQSPVSWPNGSEQQTLGCTDHQPGLEVHSCTESQRKAQTPEPMEDRAGKAGAQENLTPRSRPPRGIGPRARGTS-KRSRAGGPGPAGRC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUT6-1", "uniprot_id": "CCD9B_HUMAN", "id": "Q6ZUT6-1", "name": "Coiled-coil domain-containing protein 9B", "aln": "MISCAEQRSRQGEAGRGPAPVAP----AFLPLWLPRGCSGILSVPAVAMHSAGTPRAESPMSRQE-KDAELDRRIVALRKKNQALLRRYQEIQEDRRQAEQGGMAVTTPALLQPDGLTVTISQVPGEKRVVSRNWARGTCGPRVTNEMLEDEDAEDHGGTFCLGELVELAVTMENKAEGKRIVSEKP-TRARNQGIEGSPGGRVTRSPPTQVAISSDSARKGSWEPWS----------RPVGEPPEAGWDYAQWKQEREQIDLARLARHRDAQGDWRRPWDLDKAKSTLQDCSQLRGEGPARAGSRRGPRSHQKLQPPPLLPDGKGRGGQASRPSVAPATGSKARGKERLTGRARRWDMKEDKEELEGQEGSQSTRETP-SEEEQAQKQSGMEQGRLGSAPAASPALASPEGPKGESVASTASSVPCSPQEPDLAPLDLSLGGAGIPGPRESGCVLGLRPGAQESPVSWPEGSKQQPLGWSNHQAELEVQTCPEPQRGAGLPEPGEDRSGKSGAQQGLAPRSRPTRGGSQRSRGTAGVRRRTGRPGPAGRC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * :: * .. : . *. .**..* *:* **************************:****************.:****.*********************.. .* ** :. ** * ***.:*. ***********:.******** ::**. :*:.** .* * : *.*** ** ** * :.:* .*** ***:******************:.**** *********. *:* : *... * ***:***:*** * ** *** ****:.***::.: **:.:*********** : *: ****: :** :*** **:. * .* : .*:** ***** : * :**** .* ***..********:***. * :* : . :.***:** ***:**:**.* ::**. ***::*.*. * * *** *** .::***:.*:*****.** . *:** : * *:* *******", "identical_positions": 295, "similar_positions": 103, "identity": "53.54%" }, { "cls_id": "homologset.agr.HGNC:3349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGP3-1", "uniprot_id": "A0ABK0LGP3_RAT", "id": "A0ABK0LGP3-1", "name": "", "aln": "MECREETRTEGSRNKETPPGPTLHPLCLSPARGPCMSGPFTYQEMRMGCKAALDAGPGQDRRPLPSQRAQCLFLTIQSARDPCPALSLQPTSPDFSAATSEGWSRDVVAPAACSLRIPVRTHAGPGAHQQPCLWTPDKAQRTDSRVDSMDRSMLPLVITLLLVIYSFVPTS-LAERVGCDLQRVDSTRGEVTYTTSQVSEGCVAQVANAAHEVHVLFLNLSRRKSEVELTLQASKQNGTETREVFLVFISNENVLVKLQAPEIPLHLVYNSSLEVFKG--PKVNSTPLPSFTSKTQILDWAAT-KGTITSIAALDDPKSIVLR--LGQDPKAPPFCFPEAQKDMGVTLEWQPRTQTPVQGCHLEGVTGHKEAYVLRIRSGSEAGPRTVTVTVKLSCTSG--DAVLILQGPPYVSWLIDTNHNMQIWTTGEYSIKIFPENNIKGFELPDTPQGLIGEAR-KLNASIVT-FVEIPLTSDVSLTVSSCGGGLQTSPAPVVTTPPKDTCSPELLMSLIQPKCGNDVMTLALNKKLVQTLQCTITGLAFWDSSCQAKDQDGHLVLSSTYSSCGMKVTDHVISNEVIINLPSGLPPLRKKVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQGFVQVSMSPLTSEVTVQLDSCHLDLGPEGDMVELIQSRAAKGSCVSLLSPSPEGDPRFSFLLRVYMVPTPAAGTLSCNLALHPSTLS--QEVYKTVSMRLNIVSPDLSG---KGLVLPSVLGITFGAFLIGALLTAALWYIYSHTRAPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63961-1", "uniprot_id": "EGLN_MOUSE", "id": "Q63961-1", "name": "Endoglin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MDRGVLPLPITLLFVIYSFVPTTGLAERVGCDLQPVDPTRGEVTFTTSQVSEGCVAQAANAVREVHVLFLDFPGMLSHLELTLQASKQNGTETQEVFLVLVSNKNVFVKFQAPEIPLHLAYDSSLVIFQGQ-PRVNITVLPSLTSRKQILDWAAT-KGAITSIAALDDPQSIVLQ--LGQDPKAPFLCLPEAHKDMGATLEWQPRAQTPVQSCRLEGVSGHKEAYILRILPGSEAGPRTVTVMMELSCTSG--DAILILHGPPYVSWFIDINHSMQILTTGEYSVKIFPGSKVKGVELPDTPQGLIAEAR-KLNASIVTSFVELPLVSNVSLRASSCGGVFQTTPAPVVTTPPKDTCSPVLLMSLIQPKCGNQVMTLALNKKHVQTLQCTITGLTFWDSSCQAEDTDDHLVLSSAYSSCGMKVTAHVVSNEVIISFPSGSPPLRKKVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQAFVQVSVSPLTSEVTVQLDSCHLDLGPEGDMVELIQSRTAKGSCVTLLSPSPEGDPRFSFLLRVYMVPTPTAGTLSCNLALRPSTLS--QEVYKTVSMRLNIVSPDLSG---KGLVLPSVLGITFGAFLIGALLTAALWYIYSHTRGPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17813-1", "uniprot_id": "EGLN_HUMAN", "id": "P17813-1", "name": "Endoglin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MDRGTLPLAVALLLASCSLSPTS-LAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEP-PGVNTTELPSFP-KTQILEWAAE-RGPITSAAELNDPQSILLR--LGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEAR-MLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1Z2R986-1", "uniprot_id": "EGLN_DANRE", "id": "A0A1Z2R986-1", "name": "Endoglin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MKSICCVLVLCLLLCRRSTASES------ICELKDVSGNSNDWIVLREKPLGCWTDFQTENGTEVHIINLEDNPS------VFTVNLLKANKSVVIFTSSSAQSSHAMLFDNPAVSIYVTNKTSLTFIHPTQKPLQILTAPPAGNVSAVLRWAAETFGGVTSVTNARNPKTITFTGVKGSQNSSRCELMPETPTEKPFIHLELNEPIEALKSCYMKHEG--EKLHIINIPDG--VTIRHVSVHLLS-------DCNVVLRGPAGTHWIIKNSLRIGILSNNQIHLQSFPLR--PRMAISDNPTDIRQKALSYFSSGFISSYSEIRLN-VTNVELWITDYSISSAPTEVEKTTPSPTSPPFPVQ-----------MQLFSSPDFTTPIDN--------NSRVLSDKRVYAEISSQTFREASIRVSSCWVRSTPVTREMPFREEPCFIKDCPKRLSFSFQILQDLPAGSWDLECAVKLCGVKRINNEES-CTSETPVKRN------------VQVKPFTPTTNSCFEFGLSAVLGIAFGGFLIGVLLTG-------------------------ALWFIKIRTGHPVALG-------------------MRSTAAELSVLSISGCPCGLTKRQPVPTHPSPS--ENSSANASIGSTQSTPTSSMA--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * : **: * . : *:*: *. .: .: . .: ***:: *: .: .. :.. . :: :.. : :: :.:::. .:** :: :: *. . :* *** * :** : :*::* : *. : : *: : .. ::.* :: :: :::.: * . * *:* : *. ::*:**. . *:*. . : * :..: .: ** . :.*.* .: :* :.:.::: : *: * ..: . :.::*: : .*.*. *..* : * * . . . :. :. :.. : .:: ...::*: : . : . .* . *:***: *.. : . ::: :: * .** :: : *:: .:...*. : .: * . .**: . . :::. * * : .: :: * . . . :**:** : .:*: *.**:* ********* *: : ", "identical_positions": 89, "similar_positions": 204, "identity": "10.95%" }, { "cls_id": "homologset.agr.HGNC:33499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R950-1", "uniprot_id": "M0R950_RAT", "id": "M0R950-1", "name": "", "aln": "--------------------MAGTPAPNSHRKQSGGLEPFLGLSRSIENPPSKRARSFSETTVPDPEDPFGEHAEFTADDLEELDILASQALSQCPVAPPNLSCAHKVRR-LDGLPNSPIRKNREDIPVKDNFELEVLQIQYRELKEKLKAMEEEILIKNGEIKILRDSLHQTESVLEEQKRSHFLLEQEKTQALSEKEKEFSKKLQSLQSELQFKDAEMNELRTKLQSNERTNKLTIPSVSQVSPRKGSSVVVKSEACSPHVGKTTFPTKESFSANTPLFHPCQTEAGHKFLVGQEVSDNKAH-VGGNLLKQDVQQKILTDSWVQRKNTQGTRRPAFCSILINLLLKQPLVPGSSLGLCHLLSSGAEVPTGPILQPAGL-STLPGTSGLRTISSSDGPFSPSALREAQNLAFTGLNLVARSESSHDGDVA--GRRVFPLCQLPGAVHILPLVQFFIGLHCQALQDLTPAKKNGAPGASPTDTSHMSSGVEASPEDSVCSLESTSVASLSVLQHLVCHSGAVVCLLLSGMGTNAAAREGD--LSQTCAD--TVSASREDAHGQNQHPLLKMLLQLMAFSSTTSGQFQASVLSQCLKVLVKLAENASSDLLPRFSFVFP--MLPQCLCSELPLSCVLLAVELLSVLVDQDSLAQQLCSHSEGCLLLRLYMYITSRPDKTASETQWLQLEQEVVWLLAKLSVQSP--SPAGIVSDCQCNVEAVRALTVMLHRQWLTVRRAGGP-RTHQQKQT--VRCLRDTVLLLHSLSQKDKLFTVHCVEVLHQYDQVMPGVSMLIRALPDVTDCEEAALDDLCAAETD-LEDAEMDCS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMG1-1", "uniprot_id": "ATRIP_MOUSE", "id": "Q8BMG1-1", "name": "ATR-interacting protein", "aln": "--------------------MAGTPAPNSHRKQSGGLEPFPGLSRSIENPPSKRARSFSETTVPDPEDPFGEHAEFTADDLEELDILASQALSQCPVAPRNLSSAHKVRR-LDGLPNSPIRKSREDIPVKDNFELEVLQIQYKELKEKLKAMEEEILIKNGEIKILRDSLRQTESVLEEQKRSHFLLEQEKTQALSEKEKEFSRKLQSLQSELQFKDAEMNELRTKSQSNGRTNKPAAPSVSHVSPRKGSSVVLKSEACSPHVGKTTFPTKESFSANTPLFHPCQTEAGHRFLVGQEVSDNKNHSLGGSLMKQDVQQRILADGWMQRKDAQG-------SILINLLLKQPLVPGSSLGLCHLLSSCPEVPTGTLLQPPGL-STLPGTSGLRTISSSDGPFSPSALREAQNLAFTGLNLVARTESSHDGDMA--GRRVFPLHQLPGAVHLLPLVQFFVGLHCQALQDLAPAKKSGVPGDSATHTSCMSSGVEASPEDSIHGLESFSVASLSVLQNLVCHSGAVVCLLLSGMGTEAAAREGN--LVQTCAD--TTSASREDAHDQDQHPLLKMLLQLMASSSAASGHFQASVLGLCLKVLVKLAENASSDLLPRFSCVFP--VLPQCLGSALPLPCVLLAVELLSVLLDHDSLAWQLCSHPEGCLLLRLYMYITSRPDRTASETQWLQLEQEVVWLLAKLSVQSP--APAGIGSDCHCNVEAVRALTVMLHRQWLTVRRAGGP-RTHQQKQT--IRCLRDTVLLLHSLSQKDKLFTVHCVEVLHQYDQVMPGVSMLIRALPDVTDCEEAALDDLCAAETD-LEDSEMDCN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXE1-1", "uniprot_id": "ATRIP_HUMAN", "id": "Q8WXE1-1", "name": "ATR-interacting protein", "aln": "--------------------MAGTSAPGSKRR-SEPPAPRPGPPPGTGHPPSKRARGFSAAAAPDPDDPFGAHGDFTADDLEELDTLASQALSQCPAAARDVSSDHKVHRLLDGMSKNPSGKNRETVPIKDNFELEVLQAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTESGYKPLVGRE--DSKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQG-------SILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRAFPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQ--VLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVWLLAKLGVQSP--LPPVTGSNCQCNVEVVRALTVMLHRQWLTVRRAGGPPRTDQQRRT--VRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETD-VEDPEVECG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TCL1-1", "uniprot_id": "A0AB32TCL1_DANRE", "id": "A0AB32TCL1-1", "name": "", "aln": "MDFPPSKRLKGPQVKTGPDPFDDDIDFTQDDLEQIDIIASQAISADVQNSGSKRSFDAVLACADEPSKAPVRSGRKTFALGDACSSSTYNNTHAQRKEPSVYSTPEVSMEFLHSPADPDSARDGPSSKDGDDLYYKQLEEQQAELKKKLKEVEEEILMKNGEIRVLRDSLKQAHQEREQQRQAQIILEKEKTQAQSDREKELSRKVQSLQSELHFKEAEMNEMRGKLQSVERGGKQSGTPARQAVKSPLSRTFMTKENFSAEISKRTSPVKPGPSSDNAALSRCLLPE-----------------------EQRSQQCIASDLQKEG------------CVLLKLLLQQPLDP-SVLGLCHLLSISPDALPNMLTQHGYISPGSLSTSSSSSTDLRSFPRSPSQFHHLQSLAMSALTALSLHEPSTVSRPS----------SCPSAVHFLPLLSFHISTYCQSLEVFDSSTKSSLHSGSLSGSSDSS--LSSVLEESLSGQEELALAALRALQHIVCYSKEALEDVIR-----------------------MQTPKNMLGEIQNQMPVLRRLLQLADPAFSTAAGHREALVSCSWRILSVLAERAEDNLISRLQVVMSSPVLSKCLTLETTYSIVHLCVRFLSFIICNDEMASKLCLHDYPCPFLKIFQYVTSRPDKSSTEDAWSRLELVVIRLLTKLFTQRAGTWAALCESSCQCVNEVVRTVVVVLHRQWLKTKCRGGQTVGTQIWSSPGLQVLREALMLLHWLLLKDSAFSEHCLDVLHMYDQVIPAIRDTFRLLPDLSESEELALEEICRSETEYVEDMDVETGS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. . . . . . :. ***: . : . :*... . * : . : : . * . . *.. .. :. *:: : *: * ***:*:* :***:*:*****::*****:*:.. *:*::::::**:***** *::***:*:*:*******:**:*****:* * *: * .* : ... :. . ..:. * *....* : *.* . *:: . * :* * * : .:*::***:*** * * *.****** .: .. * : . . *. : . . . * * ::. *.**::.*. :: * * . : . *.***:***:.*.:. :**:*: : .:.:.. . * : :* * :.: *:*: * ::::* **::**:* .: :: :. . .. *.* *:*: **:* : :::. : ::: . ::* ***.:. :::.*:. *: :*.:** . . * *.*.:**.: :*.:* :** * * :* :: *:*****: : * * :** *: **:** .* . .. *.*:* *.**::.*:******..: ** * : :: **::::*** * **. * **::*** :***:*.: :* ***:::.** **:::* :**: :** ::: . ", "identical_positions": 214, "similar_positions": 253, "identity": "25.81%" }, { "cls_id": "homologset.agr.HGNC:3350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04764-1", "uniprot_id": "ENOA_RAT", "id": "P04764-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17182-1", "uniprot_id": "ENOA_MOUSE", "id": "P17182-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILRIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSQAVEHINKTIAPALVSKKVNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIAKAGYTDQVVIGMDVAASEFYRSGKYDLDFKSP-DDPSRYITPDQLADLYKSFVQNYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAASEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06733-1", "uniprot_id": "ENOA_HUMAN", "id": "P06733-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSP-DDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1X2-1", "uniprot_id": "A0A2R8Q1X2_DANRE", "id": "A0A2R8Q1X2-1", "name": "phosphopyruvate hydratase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGVKRAVKYVNEFLAPALCNQNVSVLEQEKIDKLMLDMDGTDNKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASNFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAISKAGYTDKIVIGMDVAASEFYKGGKYDLDFKSP-DDPSRYISPDKLADLYKSFVKDYPVVSIEDPFDQDDWEAWTNFTATTNIQVVGDDLTVTNPKRIAKAVSDKACNCLLLKVNQIGSVTESLQACKMAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGDKARFAGKNFRKPI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKE--IILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00925-1", "uniprot_id": "ENO2_YEAST", "id": "P00925-1", "name": "Enolase 2", "aln": "-------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDEDKSKWMGKGVMNAVNNVNNVIAAAFVKANLDVKDQKAVDDFLLSLDGTANKSKLGANAILGVSMAAARAAAAEKNVPLYQHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEAMRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKVKIGLDCASSEFFKDGKYDLDFKNPESDKSKWLTGVELADMYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAANWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDKAVYAGENFHHGDKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00924-1", "uniprot_id": "ENO1_YEAST", "id": "P00924-1", "name": "Enolase 1", "aln": "-------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKIKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDNAVFAGENFHHGDKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX11-1", "uniprot_id": "ERR2_YEAST", "id": "P0CX11-1", "name": "Enolase-related protein 2", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX10-1", "uniprot_id": "ERR1_YEAST", "id": "P0CX10-1", "name": "Enolase-related protein 1", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42222-1", "uniprot_id": "ERR3_YEAST", "id": "P42222-1", "name": "Enolase-related protein 3", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : ** ::**********:: * *:**: ********::**:*:** :*:.: **.* .** :*. :.. : . .: * :* :*.:::.:*** ***::*********:...:*.*.:*.:.**:::*:*: ::*** :**:***:***. **:*** * *.** .* **:::*:****:** : * ::* .* ******.**:* ::.*::: ** .*: .:: :*:* *.* *:: *:***:**. .* *:::. :**: *:.::: :*::*:***: :*.* :* : ..:*::.**** ** *** * .*..: ****:****:::**: * : .**.*:*********.**.****** ****:** .******* *::******:* :**. *:. ", "identical_positions": 199, "similar_positions": 144, "identity": "39.48%" }, { "cls_id": "homologset.agr.HGNC:33504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UU41-1", "uniprot_id": "SCIMP_MOUSE", "id": "Q3UU41-1", "name": "SLP adapter and CSK-interacting membrane protein", "aln": "-----------MSWWRDNFWIILAMSIIFISLVLGLILYCVCRWQLRQGRNWEIAKPSKQDGRDEEKMYENVLNSSPGQLPALPPRGSPFPGDLAPQEAPRQPSAWYSSVKKVRNKKVFAISGSTEPENDYDDVEIPATTETQHSKT-TPFWQAEVGLHSSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LNG9-1", "uniprot_id": "A0ABK0LNG9_RAT", "id": "A0ABK0LNG9-1", "name": "", "aln": "-----------MSWWRNNFWLILAVTIISISLVLGLILYCVCRWQLRQGRNWEVAKPSIQDGREEDKMYENVLNSSPGRLPALPPRSSPFPEDPAPQESPRQPSAWYSSVKKVKKKNVFDISVSTDPENDYDDVEIPATTEIQHSITPIPLWQAETGLHSSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWF3-1", "uniprot_id": "SCIMP_HUMAN", "id": "Q6UWF3-1", "name": "SLP adapter and CSK-interacting membrane protein", "aln": "MDTFTVQDSTAMSWWRNNFWIILAVAIIVVSVGLGLILYCVCKWQLRRGKKWEIAKPLKHKQVDEEKMYENVLNESPVQLPPLPPRNWPSLEDSSPQEAPSQPPATYSLVNKVKNKKTVSIPSYIEPEDDYDDVEIPANTEK-----------------ASF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:***:***::** :*: *********:****:*::**:*** :. :*:********.** :**.****. * * :***:* **.* ** *:**::*:.. *. :**:*********.** :**", "identical_positions": 81, "similar_positions": 33, "identity": "50.0%" }, { "cls_id": "homologset.agr.HGNC:33517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AI83-1", "uniprot_id": "A0A8I6AI83_RAT", "id": "A0A8I6AI83-1", "name": "", "aln": "MSRETAALACRAPKGQSGLSFVKTEEKDGVWKQDFGFQGHLQSQEVFRQQFRQFGYSDFTGPRQALNQLQKFCQQWLRPEEHSKEQILELLVLEQFLTILPMELKAWVQEHGPRNGEEAVTLLEELEREFDEPKHQNTAHGQEMICKETTLMG--MSESLSSPLQSLENHCKSELQEPQVFHERDKATLPFRVEDEDSKMATGKALTAKQEGIECVASVAMESPGRLPRETSPVQRVEETMEFLDNEKQQGSDDTSNKTSPLSSQEGGFSLAPFSKKTPTEQNIFEYNESEGILSQNLHGTTQPRTDTGKLLYACMDCGKAFCNRSKLIRHQRSHTGERPYACKECGKAFGFRADLVRHQRIHSGEKPYKCCDCGKAFGNNTGLTRHRRIHTGEKPYGCDECGRAFSQCSTLIQHKKIHSGEKPYSCEECGRAFVQSSALIQHKKIHSGDKGFKCTECGKTFWTSYVLREHQRIHTGEKPYQCNECGKSFNRSTALTVHQRTHSGEKPYECNECRKTFRHRSGLVRHQRTHTRVKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86W11-1", "uniprot_id": "ZSC30_HUMAN", "id": "Q86W11-1", "name": "Zinc finger and SCAN domain-containing protein 30", "aln": "MSGEATVLAYHAPEEQEGLLVVKVEEENYVLDQDFGLQENPWSQEVFRQKFRQFSYSDSTGPREALSRLRELCCQWLRPEVHSKEQILELLMLEQFLAILPEELQAWLREHRPENGEEAVTMLEELEKELEEPRQQDTTHGQEMFWQEMTSTGALKSLSLNSPVQPLENQCKTETQESQAFQERD------------GRMVAGKVLMAKQEIVECVASAAMISPGKLPGETHSQRIAEEALGGLDNSKKQKGNAAGNKISQLPSQDRHFSLATFNRRIPTEHSVLESHESEGSFSMNSNDITQQSVDTREKLYECFDCGKAFCQSSKLIRHQRIHTGERPYACKECGKAFSLSSDLVRHQRIHSGEKPYECCECGKAFRGSSELIRHRRIHTGEKPY---ECG-------------------------ECGKAFSRSSALIQHKKIHTGDKSYECIACGKAFGRSSILIEHQRIHTGEKPYECNECGKSFNQSSALTQHQRIHTGEKPYECSECRKTFRHRSGLMQHQRTHTRV--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *::.** :**: *.** .**.**:: * .****:* : *******:****.*** ****:**.:*:::* ****** **********:*****:*** **:**::** *.*******:*****:*::**::*:*:*****: :* * * * **.**:*.***:**:* **.*.*:*** .:*.:**.* **** :*****.** ***:** ** . : .**:: ***.*:* .: :.** * *.**: ****.*.:: ***:.::* :**** :* * :. ** .** : ** *:*******: ******** ****************.: :***************:**:***** ..: * ************ *** ***:** :***********:***.::* ***:* * :* ************:*********:*:*** *** *:*******.************::******** ", "identical_positions": 325, "similar_positions": 105, "identity": "60.63%" }, { "cls_id": "homologset.agr.HGNC:33519", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NND2-1", "uniprot_id": "A0ABZ3NND2_RAT", "id": "A0ABZ3NND2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------MVLPDGEGRNEEDSRQGQPG-----------SEATAVGGDEAEELSG-----------QGGRPVRTAGLMDN--QEDNGATGCDQENEKQPKEPVLKDMGTTEDVQSAPELVTRMHPMPLRVCRVEPISVRVPRVQRIQRMVPQTACATYGASWTAYSTYGALYTGYVTYSALCTAYATYGASCAAYATYGALWTPSATYGVPCTAYAIYGALCTTYATYSASCTTYATYGAPWTAYATYGAPWTAYVPDSAPWTAYATYGACTAYATYGAPYTAYVTYDTAWTASSMYGALWTAYATYGDLCTGYATYGALCTIYAPSGALCTAHSAYGSLYTTYATYGAPCTAYATCGAPWTVYVTYTALCKAYVMYGAPCTSYAIYGALCTAFTPYGAFCTAYATYGVLWTAFDTCDALFTAYATYNAPSSNVQPEPVLVPRRHLHDRFTDPELQELERVFQRNHYLSAEERKQLARGMGVSEAKLQRWFKKRREHFRREQSQSGG------------APPGNTPP--------------------------------------LSEDGAGALVYHP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "L7MUB9-1", "uniprot_id": "L7MUB9_MOUSE", "id": "L7MUB9-1", "name": "", "aln": "-------------------------------------------------------------------------------------MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPG-----------SGVSAAEGYRAGELS------------AGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVK----------PMSGPWSTVNPVRVLVP------------------------------------------------------------------------------------------------------------------------------------------------EFLHGWQQS-----------------------------------------------------------------------------------------------------------------------------------------------------------FNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AWM0-1", "uniprot_id": "A2AWM0_MOUSE", "id": "A2AWM0-1", "name": "", "aln": "--------------------------------------------------MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESA-----------LGATAARGRGKEALNG-----------ESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEA--------PRQVPRRRLHHR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7M4-1", "uniprot_id": "RHF2B_HUMAN", "id": "P0C7M4-1", "name": "Rhox homeobox family member 2B", "aln": "---------------------------------------------------------------------------------MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPE-----------QGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGNLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLE-------PGNAQQPNVHAF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMA------------RNMLPFMA--------------------------------------VGQPVMVTAAEAITA---------------PLFISGMR--DDYFWDHSHSSSLCFP------MPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWH1-1", "uniprot_id": "Q9VWH1_DROME", "id": "Q9VWH1-1", "name": "Homeobox domain-containing protein", "aln": "-----MIRATSCALSTRPLRSPKAPSHRHKIRSIKTGARSPRDSFQLDYSIDFFKTYIDTQRFYAGHKLDFKHQSCAGGPGSGGAGGPGPGGGGGASGVVVVGGTSNSNNPAAAQQQQQQQQQQQQQQQQQS-----------GGNNPSNGSNSAVALSLAHPHAHASHAHSSHAHGSHAHALAIAHGHHGLLPSVVPQQQQQQQQQQQQQQQQQQAQQLPPGVGVASPLQQQQQQQQQQQQQQQQQQQQQQLINNGGVSAGTPTLLIGNGPSSSGAGTGSVSAAAAAAAAAAAASSSSSSLPHVAPHSLGLSPQSSADSQQFNIFPAIFSRQLNFSAGGQGGKLSMDELRPNLVGGLLGLQQGLLEDHASMQHGGVGQDTKFMSFQDQRLMGIGGSHEN---------------------RLLSLASSVQDTRSPITTLEKSSSSSLNHQRKCSSTPEDFSALYSGLPTPGMDSSSHHHTPAHTPPSRLSDHTISAEGAFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQHAGHTPTTASCPTPARRRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQNRRAKYRKQEKQLQK------------ALAPSVIP--------------------------------------SCNGMMRNIQGYSVSRGYQPYPHHNTMNRYPQDLFQMG--ASSYPGMTQPFSMAHS------TNMGSVGVRQDSMGEFHGMSPEDEWYNKSLSALRMNSSHHPNLSAPMLQYQT------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2P8-1", "uniprot_id": "Q9W2P8_DROME", "id": "Q9W2P8-1", "name": "", "aln": "----------------------------------------------------------------------------MMTTTTSQHHQHHPIMPPAMRPAPVQESPVSRPRAVYSIDQILGNQHQIKRSDTPS-----------EVLITHPHHGHPHHIH---------HLHSSNSNGSNHLSHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQ------------DKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAAS------AGYPQNLSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQSPNSAAGASSNASTPVSVVTKGED----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KSE4-1", "uniprot_id": "Q7KSE4_DROME", "id": "Q7KSE4-1", "name": "", "aln": "MEHDSFDDPIFGEFGGGPLNPLGAKPLMPTTTAMHPVMLGSVHELCSQQQQQQQQQRLPDCNTILPNGGGGGAGSGGAGGSPNYVTKLDFVNKMGCYSPSQKYEYISAPQKLVEQQQQQQHHHQHHQHYTATPPPSHNGILLHKQSSQQQQQQQQQLVGILDYHPLNGKLDYSSSPKDQYEPQQLQHLYGGSPHHLDHLDHGSDGLLQDSSPVMINGGSAGGKLKKPDEMCSQLEAGGAGVTPPSSSSTVVNGTTNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGNANSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQTTTVTPPGSMDSWTSYQTPYELTPQFSLLSPAASPYGTYSGQYGAYVHESQLFPMRHYEYGSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTAQQQQLADGTLVTVHAHQQQQQQQQQLNGKYLSAEEAKYVHLQCHQSGGGLELSPGASCHLVEAQGQHYVTTATGGAASAGGTSSDDNDSGGMQTVIKSEEVSQQQQQQQGQSYVLPPFLH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9XZU0-1", "uniprot_id": "Q9XZU0_DROME", "id": "Q9XZU0-1", "name": "", "aln": "-----------------MDKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIGGLGGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPDTPPQ-----------SSNSLDNELKASYGTG-----------AMSPSRLSPNIFLNLNIDHLGLERGGSGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHPPQQHASDPIHAGS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSHHQQQQQQHQQEQHNPQLHPGLEFAASLSLDMTDGSSAYDEMKFLSVDVDQFTIDS-----------FKADCILS--------------------------------------MEQSQMQAYGGHSQLVG-------------SSNELCLDGIGMSSFGMEEGEPKSPPSLLVLDKSLPSLSIGVEGIADLVEQLHHHQHEGGPVGGGVITGDVM------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : . :* : . : : : . ", "identical_positions": 1, "similar_positions": 14, "identity": "0.12%" }, { "cls_id": "homologset.agr.HGNC:33522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPC3-1", "uniprot_id": "D3ZPC3_RAT", "id": "D3ZPC3-1", "name": "", "aln": "-MASGGLLVAGASFAAFQGLHWGLQLMPTPES-VRDRWMWRNIFVSLMHSLLSGTGALVGLWLFPQMVTDPIYDHPSWARVLVAVSVGYFVADGVDMLWNQTLAQAWDLLCHHLVVVSCLSTAVVSGHFVGFSMVSLLLELNSICLHLRKLLLLSHKASSLAFRVSSWATLTTLVLFRLLPLGWMSLWLFQQHYQVSLALVILCGTGLVTVGSISISLGVRILIKDVLQPRPYPFILVHKETQQTKTCEP---VTRNNSTLSLKG---------------MEVFSS----VNPQGGGAGKRRW---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC26-1", "uniprot_id": "TLCD2_MOUSE", "id": "Q8VC26-1", "name": "TLC domain-containing protein 2", "aln": "-MASWGLLVAGASFTAFRGLHWGLQLLPTPKS-VRDRWMWRNIFVSLIHSLLSGVGALVGLWQFPQMVTDPINDHPPWARVLVAVSVGYFAADGVDMLWNQTLAQAWDLLCHHLAVVSCLSTAVVSGHYVGFSMVSLLLELNSICLHLRKLLLLSHKAPSLAFRVSSWASLATLVLFRLLPLGWMSLWLSRQHYQLSLALVLLCVAGLVTVGSISISTGIRILTKDILQSQPYPFILMHKET---KTREP---VARNTSTLSLKGSRYLYSTAAAALGGHLMVLASPKRCMTPSVLGLQERRLEPGKVAHADNASTWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGC4-1", "uniprot_id": "TLCD2_HUMAN", "id": "A6NGC4-1", "name": "TLC domain-containing protein 2", "aln": "-MAPTGLLVAGASFLAFRGLHWGLRRLPTPESAARDRWQWWNLCVSLAHSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHHQVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHEKTRGTRTRRDNGPVTSNSSTLSLKD-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WGS4-1", "uniprot_id": "TLCD2_DANRE", "id": "A8WGS4-1", "name": "TLC domain-containing protein 2", "aln": "MELNSVILTTGSSVGFFKLVNYGLGKLPIPETARRNAWKWNNISTSFVHSLITGVWSVLCFCMHPQMAEDLIETHSVFSHALVSVSIGYFIYDFLDMVINQKIIHSWELLFHHVVVITCFGISVLTCRYVGFAVVALLVEINSVFLHLRQVLRMANLAKSTFYRVNSMINLGTYVVFRINTLAWMTRWLVLNRDLIPLFSYTIGSVGLAIMTAMNIVLFYRLMRSDFMKASREKELRKEKEKEKDM------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.:*:*. *: :::** :* *:: *: * * *: .*: ***::*. ::: : .***. * * *. :: .**:**:*** * *:: **.: ::*:** **:.*::*:. :*:: ::***::*:**:*:** ****::* ::. * * : *.* .* * .:**: .*.**: ** :: :.* : **. : :.* *:: .*.::. .::. ", "identical_positions": 75, "similar_positions": 88, "identity": "23.58%" }, { "cls_id": "homologset.agr.HGNC:33525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AHC5-1", "uniprot_id": "A2AHC5_MOUSE", "id": "A2AHC5-1", "name": "Ferritin", "aln": "---------------------------MAEAP-------SRVRQNYDWQCEDAINTHIQLRLYASYVYMSMAVYFDRDDVAQENFKRFFLTKSHNCQTSAEMFMHLQNKRGGCISLQDIARPERDSWHGGFQAMECAFHMEMLINQSLLNMHEVAKEKGDPHLCHFLEQNCLDQQVDILKEMSGYLTNLRQMGAIEHNLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AHC6-1", "uniprot_id": "A2AHC6_MOUSE", "id": "A2AHC6-1", "name": "Ferritin", "aln": "---------------------------MAEAP-------SRVRQNYDWQCEDAINTHIQLRLYASYVYMSMAVYFDRDDVAQENFKRFFLTKSHNCQTSAEMFMHLQNKRGGCISLQDIARPERDSWHGGFQAMECAFHMEMLINQSLLNMHEVAKEKGDPHLCHFLEQNCLDQQVDILKEMSGYLTNLRQMGAVEHNLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MX2-1", "uniprot_id": "FH17E_MOUSE", "id": "Q99MX2-1", "name": "Ferritin heavy polypeptide-like 17E", "aln": "---------------------------MAEAP-------SRMQQNYDWQCEDAINTHIQLCLYASYEYMSMAVYFDRDDVAQENFKRFFLTKSHNCQTSAEMFMHLQNKRGGCSSLQGIARPERDSWHGGFQAMECAFHMEMLINQSLLNMHEVAKEKGDPHLCHFLEQNCLDQQVDILKEMSGYLTNLRQMGAVEHNLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K1G6-1", "uniprot_id": "A0A0G2K1G6_RAT", "id": "A0A0G2K1G6-1", "name": "Ferritin", "aln": "---------------------------MAEAP-------SQVRQNYDWHCEDAVNTHIQLRLYASYVYMSMAVYFDRDDVALGNFKRFFLSKSHECQAKAEVFMHLQNTRGGCLSLHDIARPERDSWHGGSQAMECALHMEMMINQSLLNMHEVAKEKGDAQLCHFLEQNFLNQQVEVLKEVGGYLTNLRQMGAQEHSLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZC26-1", "uniprot_id": "D3ZC26_RAT", "id": "D3ZC26-1", "name": "Ferritin", "aln": "---------------------------MAEAS-------SQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIZ8-1", "uniprot_id": "D3ZIZ8_RAT", "id": "D3ZIZ8-1", "name": "Ferritin", "aln": "---------------------------MAEAS-------SQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AUI2-1", "uniprot_id": "A0A8I6AUI2_RAT", "id": "A0A8I6AUI2-1", "name": "Ferritin", "aln": "MGFVRGPRRHQRQRCPPHFQRYRAANALVFMPPPIFSPPSDVRQNFHTDCEAAINRHVRLQLSTSYVYLSMCFYFDREDVALENFSRYFLNKSHECTRNAEIFLALQNQRGGRISLRTIYKPDCDNWIGGLPAMERAFQLELHLNQSLVAMYQLAARKRDGHLCSFLQTHFLRKQVAVLKEMSSFLISMRQMGSPEVGMAEYLFGKLSLGDNPKEK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GIM8-1", "uniprot_id": "A0A8I6GIM8_RAT", "id": "A0A8I6GIM8-1", "name": "Ferritin", "aln": "---------------------------MTTIP---------TGKNFHTDCEAAINRHVRLQLSTSYVYLSMCFYFDREDVALENFSRYFLNKSHECTRNAEIFLALKNQRGGRVSLRTIYKPDCDNWIGGLPAMERAFQLELHLNQSLVAMYQLAARKRDGHLCSFLQTHFLRKQVAVLKEMSSFLISMRQMGSPEVGMAEYLFGKLSLGDNPKEK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7X4-1", "uniprot_id": "FHL19_HUMAN", "id": "P0C7X4-1", "name": "Putative ferritin heavy polypeptide-like 19", "aln": "----------------------------------------------------------------------MAFYFDQDDAALEHFDRYFLRQSQEKREHAQELMSLQNLRGGRICLHDIRKPEGQGWESGLKAMECTFHLEKNINQSLLELHQLARENGDPQLCDFLENDFLNQQAKTIKELGGYLSNLHKMGAPEAGLAEYLFNKLTLGRSQKHTRAQTGPTATGCLPLLAPPGGTSMFPFQNILFIFLLSVLPLLAIKLSVLKAIKVSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYH1-1", "uniprot_id": "Q9VYH1_DROME", "id": "Q9VYH1-1", "name": "Ferritin", "aln": "--------------------------MAWCFRDIRRHMCMLVRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMTYMNKRGGLIILSSVPQP-LPCFASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIEANFLQEQVDGQKILADYIS---QLEKAQNQVGEFLFDKYMGSGMHPAK-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :**:.* : : *:** * : .: :: * *** * : :* : . *:: ::::* :*: *: :: :* : * :** *: . * :*. * :..:: :: : :.*:**.* . ", "identical_positions": 30, "similar_positions": 47, "identity": "11.07%" }, { "cls_id": "homologset.agr.HGNC:33527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32T7F9-1", "uniprot_id": "A0AB32T7F9_DANRE", "id": "A0AB32T7F9-1", "name": "Insulin", "aln": "MGTFVFPLMPSRAMGQAAGRYISSTIQAQSWPLFTDSAHSGKGCACPQSVSTMVLLLQA-SVLILLLASLPG-SQSSPSQHLCGSSLVDALYLVCGPRGFFYTNRGRRDLE-TLLALLSNLA-------------------------GYEAADAD-PLKEKVMKM-KRGIVEQCCHRPCTIYHLEDYCS---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O73727-1", "uniprot_id": "INS_DANRE", "id": "O73727-1", "name": "Insulin", "aln": "----------------------------------------------------MAVWLQAGALLVLLVVSSVS-TNPGTPQHLCGSHLVDALYLVCGPTGFFYNP--KRDVE-PLLGFLPPKS-------------------------AQETEVADFAFKDHAELIRKRGIVEQCCHKPCSIFELQNYCN---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P01322-1", "uniprot_id": "INS1_RAT", "id": "P01322-1", "name": "Insulin-1", "aln": "----------------------------------------------------MALWMRFLPLLALLVLWEPKPAQAFVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVPQLELGG-------------------------GPEAGDLQ-TLALEVARQ-KRGIVDQCCTSICSLYQLENYCN---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8WCM5-1", "uniprot_id": "INSR2_HUMAN", "id": "F8WCM5-1", "name": "Insulin, isoform 2", "aln": "----------------------------------------------------MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQASALSLSSSTSTWPEGLDATARAPPALVVTANIGQAGGSSSRQFRQRALGTSDSPVLFIHCPGAAGTAQGLEYRGRRVTTELVWEEVDSSPQPQGSESLPAQPPAQPAPQPEPQQAREPSPEVSCCGLWPRRPQRSQN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: :: .:* ** : . *****. **:******* ****. :*: * * . . . : .. . :: * . . :* . ", "identical_positions": 27, "similar_positions": 26, "identity": "10.71%" }, { "cls_id": "homologset.agr.HGNC:33529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U301-1", "uniprot_id": "AKAP2_RAT", "id": "Q5U301-1", "name": "A-kinase anchor protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEIGVSVAECKSVPGITSTPHSKDHSSPFYSPSHNGLLTD----------------HHESLDNDVAREIQYLDEVLEANCCDSSVDG-------TYNGISSPEPGAAILVSSLGSPAHSATKVEPIEKASGRQLP-------------PHIELSRSPSDSMAEGERANGHSTD-------------------------QPQDMLGNSLQAPASPSSS--------------------------------------TSSHCSS-----------------------------------------------------------RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEEDEHEKEQFCIRKVRPSEEMIELEKERRELIRSQAVKKNPGIAAKWWNPPQKKTIEEQLDEEHLESHRKYKERKEKRAQQEQLQLQQQQQQQLQQ----LQQLQQQ------QQQQLSTSQLCTAPAA-HEHLDSIEHTKEDVVTEQIDFSAARKQFQQMENSRQ-TLAKGQSTPRLFSIKPFYKPLGSINSDKPPTILRPATIGGTV--EDSSTQAAKEQKALCVSESQSAGAGTGNAATQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDEDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETPNALQENSLADFSLPQTPQTDNPSEGR-EGVSKSFSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDKAEVHTSKEGSEQQEPGAMVEEAGSQAPGSEKPQGMFAPPQVSSPVQEKRDVLPKILPGEDKTLREKGPSQPPTAVQPSGPVNMKETRPEGGYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVRQSTP--SPRAQNAPSLPSRTTCYKTAPGKIEKVKPPP--SPTTEG---PSLQPDLAPEEAAGAQRPKNLMQTLMEDYETHKSKRRERMDDSS-------------VLEATRVNRRKSALALRWEAGIYANQEEEDNE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54931-6", "uniprot_id": "AKAP2_MOUSE", "id": "O54931-6", "name": "PALM2-AKAP2 fusion protein", "aln": "-------------------------------------MAEAELHKERLQAIAEKRKRQTEIEGKRRQLDEQVLLLQHSKSKVLREKWLLQGVPAGTAEEEEARRRQSEEDEFKVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDLQKSFSTADG----------------------------------ASGWSTVLLQGDELTADPIGTN-ADMAIQKPPQ----LSEDANQLRSKQDNCGDSRLEPAASSLSPDHKN---------------MEIGVSVAECKSVPGVTSTPHSKDHSSPFYSPSHNGLLAD----------------HHESLDNDVAREIQYLDEVLEANCCDSSVDG-------TYNGISSPEPGAAILVSSLGSPAHSVTEAEPTEKASGRQVP-------------PHIELSRSPSDRMAEGERANGHSTD-------------------------QPQDLLGNSLQAPASPSSS--------------------------------------TSSHCSS-----------------------------------------------------------RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEEDEREKEQFCVRKVRPSEEMIELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHRKYKERKEKRAQQEQLQLQQQQQQQLQQQQLQQQQLQQQQLQQQLQQQQLSTSQPCTAPAA-HKHLDGIEHTKEDVVTEQIDFSAARKQFQLMENSRQ-TLAKGQSTPRLFSIKPYYKPLGSIHSDKPPTILRPATVGGTL--EDGGTQAAKEQKAPCVSESQSAGAGPANAATQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDEDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETPSALQENSLADFSLPQTPQTDNPSEGR-EGVSKSFSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDKAEAHTSKEGSEQQEPEATVEEAGSQTPGSEKPQGMFAPPQVSSPVQEKRDILPKNLPAEDRALREKGPSQPPTAAQPSGPVNMEETRPEGGYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVRQSTP--SPRAKNAPSLPSRTTCYKTAPGKIEKVKPPP--SPTTEG---PSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEEDNE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2D5-4", "uniprot_id": "PLAK2_HUMAN", "id": "Q9Y2D5-4", "name": "PALM2-AKAP2 fusion protein", "aln": "-------------------------------------MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQ----LSEDDIWLKSEGDNYSATLLEPAASSLSPDHKN---------------MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTD----------------HHESLDNDVAREIRYLDEVLEANCCDSAVDG-------TYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAP-------------PHIELSNSSPDPMAEAERTNGHSPS-------------------------QPRDALGDSLQVPVSPSST--------------------------------------TSSRCSS-----------------------------------------------------------RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ----------------------PPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ-AVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPP--EDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQ--SPRTKNAPSLPSR-TCYKTAPGKIEKVKPPP--SPTTEG---PSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEEDNE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U0R7-1", "uniprot_id": "A0AB32U0R7_DANRE", "id": "A0AB32U0R7-1", "name": "", "aln": "MLVTAAERRRGKPEREEKGEDAAMMGTAILRKDPAYEMAEAELHKERLQALAEKRKRQAEIEDKRRQLDELVLQLQHFKSKAMRERWLLQGTPAALQEEDEDRRKQVEQDELHIKRLEDTIHRLESEICHLENEELQISAKEQVLRERLRETERSIEDLQKSLQNQDGDAVNYNCSQIPGLPELNSQTPVSASGDHQPPRKPALYAMEINVEKDRKTGATKILSASAVSPQDAHQRGVKVYDDGRKVIYEVRSGGSTTMENGTHAWSPGEMNQLMQQVGGKQQPSDGARVTVTPAEPQQTGGQLSAKEPKQDKKQNHSKGYEGEVTETPKASADKPVTMIFMGYHSIEDEEESKKLLGFDGTIKAEIVLIDEDDEKSLREKTVTDISTIDGNAADLVSGRPLSDTTELSSEGKEESSTKELPSTGSEKARSVLLTAENGLYPSATARFSDPQKSPVHSEDDSELKRDRSLKTVSFFDSVSVISGGQSNMELGVQTETQQSYMSSGQNKVKHGGEGLDSEVAQEILYLDEVLEANCCDPRAEMTSNGTSSPDTESIRVHGTGPSVHTCDTTALNHHEVVLEGKKQTTFVDDNYNTKPNGHAAMIGNNGTRSPESPRTAMKKEARFELRPFHEEKKPSKLFDTP--TEKEIRVKKVRPSEEVAELERERLELIRGQAVKKNPGIAAKWWNPPQEKTLEEELEPEQLESLRKYEERKQRKPETNRMPQAAPRQT---------------------------TTFIQPEIAN-----------KEDVVMEEIDFSAARKQFLQMEQSKHPTVPKRNVAPQLYSAKPFFRTPEVTHVERSCGSVTVANQEGVTSYDGSEVTTVKAEKIYCCS------------------GESFIPTKDG-LSQNEMKDDDFTCARAVMTIVKDED---VDLCQRSFNSSHHTEEIDSGLDDLSLRSQDTTVLETLSNDFSMDNISDSGASNETMSAYLENSLGEYSFPSTPMATTPINGKHEISIKSPGDQ-----IGTYQGDGLTEEELEYHAGILVQNAIQQAIAQQNDKWEPLQATQHSSP-ITERHVESVQPQP-LVERP-TVTPPPKVPSPLQEKE-------TAPQITIAQATPVIPMNNYKPPSPSPPPNEKPEFSYFSKYSEAAELRSTATVTRAQETEVTSGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQAQTLHPPRAQKLKASTQPSKLVLTGKTAPGKIEKVRPAPPASPCSSDGALPSPLSDLGSDDSGGAQRPKNFMQTLMEDFETHKVKRREKAEDNSFVHS-----VTSEVLEATRVTRRKSNMAVRWEAGIYANQEDAEEEEEEEEE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *: ** :.. * *: .. :. . :* ::* ::: :*. *:: :::: :* .::*: *. * .. *: : .*. **.. . . * *.:: :: * .. * *.. ::: ::: ** . *.. ** . :. * *: **. ** *. * . *::****:****.***:*******: ::: ::*******: ***:** ****.******************:**:**:*: *:*** :**:***:::.: ::: * .: . * ***:* *:********** **:*:: ::.* : :*:*:* **:::. : ::. .. * :.. . :.* :* * *:* * **: :*.:**.****:*:***:* :* .**.* * **:*****:**:***************************** .* ****.::*:*.** : .* :*: * ** .*: .* .. .:: ***:**:***********:* ** : : :. . **.. . . *:* : **:*.**:***. .. : :: : * * :*..* : :** .***************:: :**::* ***********************************. : : : :.. .. **********:*.* ** :.. ** .**..:::.*:*****:*******:**** ****: :*.* *******.**** :*:***********: ::* ", "identical_positions": 363, "similar_positions": 229, "identity": "26.77%" }, { "cls_id": "homologset.agr.HGNC:3353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17183-1", "uniprot_id": "ENOG_MOUSE", "id": "P17183-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERDLPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09104-1", "uniprot_id": "ENOG_HUMAN", "id": "P09104-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07323-1", "uniprot_id": "ENOG_RAT", "id": "P07323-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAEKDLPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRCITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGEEARFAGHNFRNPSVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKE--IILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00925-1", "uniprot_id": "ENO2_YEAST", "id": "P00925-1", "name": "Enolase 2", "aln": "-------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDEDKSKWMGKGVMNAVNNVNNVIAAAFVKANLDVKDQKAVDDFLLSLDGTANKSKLGANAILGVSMAAARAAAAEKNVPLYQHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEAMRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKVKIGLDCASSEFFKDGKYDLDFKNPESDKSKWLTGVELADMYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAANWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDKAVYAGENFHHGDKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00924-1", "uniprot_id": "ENO1_YEAST", "id": "P00924-1", "name": "Enolase 1", "aln": "-------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKIKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDNAVFAGENFHHGDKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX11-1", "uniprot_id": "ERR2_YEAST", "id": "P0CX11-1", "name": "Enolase-related protein 2", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX10-1", "uniprot_id": "ERR1_YEAST", "id": "P0CX10-1", "name": "Enolase-related protein 1", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42222-1", "uniprot_id": "ERR3_YEAST", "id": "P42222-1", "name": "Enolase-related protein 3", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : ** : **********:: * *:**: ********::**:*:** :* .: **.* :** ::*. :.. ::.: : * :* :*::::.**** ***::*********:...:*.**:: :.**:::*:*: ::*** :**:***:***. **:*** * *.** :* :*:::*:**** ** : * ::* .* ******.**:* .:**::: .** .*: :: :*:* *.* *::**:***:**. :* *: :. :*. *:.::: :*::*:***: :*.* :** : ..:**:.**** ** ** *:*:*..: ****:****:::*:* * : .**.*:*********.**.****** ****:** .******* *:::*****:* :**. *:. . ", "identical_positions": 201, "similar_positions": 142, "identity": "39.88%" }, { "cls_id": "homologset.agr.HGNC:33531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01768-1", "uniprot_id": "NDKB_MOUSE", "id": "Q01768-1", "name": "Nucleoside diphosphate kinase B", "aln": "-MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHDWVYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19804-1", "uniprot_id": "NDKB_RAT", "id": "P19804-1", "name": "Nucleoside diphosphate kinase B", "aln": "-MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFKPEELIDYKSCAHDWVYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22392-1", "uniprot_id": "NDKB_HUMAN", "id": "P22392-1", "name": "Nucleoside diphosphate kinase B", "aln": "-MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B3-1", "uniprot_id": "A0AB13A7B3_DANRE", "id": "A0AB13A7B3-1", "name": "Nucleoside diphosphate kinase", "aln": "MSAKTERTFIAVKPDGVQRGLMGEIIKRFEQKGFRLVAMKFLQVCVLMVDQDAVASEDLLKQHYIDLKDRPFYPGLVKYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIEVGRNIIHGSDSVDSANTEISLWFKPEELVSFKSCAQQWIYE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08879-1", "uniprot_id": "NDKA_DROME", "id": "P08879-1", "name": "Nucleoside diphosphate kinase", "aln": "MAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTW-----------ASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36010-1", "uniprot_id": "NDK_YEAST", "id": "P36010-1", "name": "Nucleoside diphosphate kinase", "aln": "MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVK-----------ADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ***** :*********:.:*:.***:**::***:*: *... *::** : :**:* :*.:*.***::. **** :**: ** :** *** .* ******** *::***: ****:*.**: ** ***: :**: : . .*:**", "identical_positions": 79, "similar_positions": 45, "identity": "48.17%" }, { "cls_id": "homologset.agr.HGNC:3354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15429-1", "uniprot_id": "ENOB_RAT", "id": "P15429-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21550-1", "uniprot_id": "ENOB_MOUSE", "id": "P21550-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13929-1", "uniprot_id": "ENOB_HUMAN", "id": "P13929-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAIFAGRKFRNPKAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKE--IILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00925-1", "uniprot_id": "ENO2_YEAST", "id": "P00925-1", "name": "Enolase 2", "aln": "-------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDEDKSKWMGKGVMNAVNNVNNVIAAAFVKANLDVKDQKAVDDFLLSLDGTANKSKLGANAILGVSMAAARAAAAEKNVPLYQHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEAMRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKVKIGLDCASSEFFKDGKYDLDFKNPESDKSKWLTGVELADMYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAANWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDKAVYAGENFHHGDKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00924-1", "uniprot_id": "ENO1_YEAST", "id": "P00924-1", "name": "Enolase 1", "aln": "-------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKIKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDNAVFAGENFHHGDKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX11-1", "uniprot_id": "ERR2_YEAST", "id": "P0CX11-1", "name": "Enolase-related protein 2", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX10-1", "uniprot_id": "ERR1_YEAST", "id": "P0CX10-1", "name": "Enolase-related protein 1", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42222-1", "uniprot_id": "ERR3_YEAST", "id": "P42222-1", "name": "Enolase-related protein 3", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : ** : **********:: * * **: ********::**:*:** :*..: **.* :** ::*. :.. ::: .: * :* :*.:::.**** ***::*********:...:*.**:*.:.**:::*:*: ::*** :**:***:***. **:*** * *.** :* **:::*:****:** : * ::* .* ******.**:* ::**::: ** .*: .:: :*:* *.* *:::*:***:**. .* :: :. :*.: *:.::: :*::*:***: :*.* :*: : ..:**:.**** ** *** *:*:*..: ****:****:::*** * : .**.*:*********.**.****** ****:** .******* *:::**** :* :**. *:. . ", "identical_positions": 201, "similar_positions": 145, "identity": "39.88%" }, { "cls_id": "homologset.agr.HGNC:33543", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50237-1", "uniprot_id": "ST1C1_RAT", "id": "P50237-1", "name": "Sulfotransferase 1C1", "aln": "---------------MSLEKMKD------LHLGEQDLQPETREVNGILMSKLMSDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPSPLNSG--LDLANKMPSPRTLKTHLPVHMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIEQFKAGKVLWGSWYDHVKGWWDVKDQHRILYLFYEDMKEDPKREIKKIAKFLEKDISEEVLNKIIYHTSFDVMKENPMANYTTLPSSIMDHS-----ISPFMRKGMPGDWKNYFTVAQSEDFDEDYRRKMAGSNITFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VR3-1", "uniprot_id": "ST1C1_MOUSE", "id": "Q80VR3-1", "name": "Sulfotransferase 1C1", "aln": "---------------MPLEKLKD------LHLDEQNMQPETREVNGILMSKMMSENWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPPPLNSG--LDLANKMPSPRTLKTHLPVQMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIETFKAGKVLWGSWYDHVKGWWDVKDKHRILYLFYEDMKEDPKREIKKIVKFLEKDISEEVLNKIIHHTSFDVMKQNPMANYTTLPSSIMDHS-----ISPFMRKGMPGDWKNYFTVAQSEDFDEDYRKKMAGSTITFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IMI6-1", "uniprot_id": "ST1C3_HUMAN", "id": "Q6IMI6-1", "name": "Sulfotransferase 1C3", "aln": "---------------MAKIEKNA------PTMEKKPELFNIMEVDGVPTLILSKEWWEKVCNFQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQTLDRHAFLELKFPHKEKPD--LEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHS-----ISPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1L8-1", "uniprot_id": "Q9W1L8_DROME", "id": "Q9W1L8-1", "name": "", "aln": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAIS-YFHHWRGMVG-YQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF40-1", "uniprot_id": "A0A0B4KF40_DROME", "id": "A0A0B4KF40-1", "name": "", "aln": "---------------MNRVQVTP-------RSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCGTTWMQELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSRYYHGVSFGFN-YGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHEN-AGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : ::: : **: :.* .*.**** :*: :: *: *.: . : * .*:* . : : **: :*:**. ::* .:*. . *::** **. *. :* *.. . . :: . . . * :: :. ::: :* :* : *..: :**:: :.:: :::: * ** *:.** *: .: *:*:* .. *: :. .. : : :.: ", "identical_positions": 46, "similar_positions": 94, "identity": "8.36%" }, { "cls_id": "homologset.agr.HGNC:33547", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA48-1", "uniprot_id": "D3ZA48_RAT", "id": "D3ZA48-1", "name": "", "aln": "MNIEVGNVSYTGAIVSWSSSEPCLEDYYHIMYRPNWNSIFSSYLRYSFHREEKVPRTITSVALEHLAPSTLYFLCISCKKAAFPYSHYCTMFHTLDKSPLAAGGSLVDPQISLWVLMAILLACFTAVLAFICLQFWCIRCHEPRWSYRAGHMEEANGLVRWPEETPALGQREEDLQGFPLEELPRKNSGARAEAELEAEASQDVIDVVALAREVGDQPAILPHYKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJN4-1", "uniprot_id": "FNDC9_MOUSE", "id": "Q8BJN4-1", "name": "Fibronectin type III domain-containing protein 9", "aln": "MNIEVGNVSHTGAIISWSPSEPCLEDYYHIMYRPNWNSIFSGYLRYNFHHEEKVPRTITSVALEHLAPSTLYFLCISCKKAAFPYSHYCTMFHTLDKSPLAAGGSLVDPQISLWVLMAILLACFTAVLAFICLQFWCLRCHEPRWSYRAGQMEEANGLVRWPEETPALGQREEDLQGFPLEELPRKNSGARAKAEPEAEAIQDALEVVALAREIGNQPAILPHYRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBE3-1", "uniprot_id": "FNDC9_HUMAN", "id": "Q8TBE3-1", "name": "Fibronectin type III domain-containing protein 9", "aln": "MNIEVGNISYTGAIISWSSSEPCLEDYYHIMYRPNWNSIFSGYLRYSFHHEEKVPRTISSVVLEHLAPSTLYFLCISCKKAAFPYRHYCTMFHTLDKSPLAPGSSLVDPQISLWVLMAILLACFTAVLAFICLQFWCVRCHEPRWSYRAGHMEEANGLVRWPEEAPDLGQREEDLQGLPLVEMPRKNS--RDGAELDPEANQDAPDAGALQRGGGDPPAILPHCGE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:*:****:***.**********************.****.**:********:**.*********************** ***************.*.*********************************:************:*************:* **********:** *:***** * ** :.** **. :. ** * *: ****** *", "identical_positions": 187, "similar_positions": 22, "identity": "82.74%" }, { "cls_id": "homologset.agr.HGNC:3355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFX0-1", "uniprot_id": "Q9VFX0_DROME", "id": "Q9VFX0-1", "name": "Aminopeptidase", "aln": "-------------------MIVTAKLVAIGLGLALTAFTVSTIVLAVQKANLKSDLRDAQEKLDLLEAGYTSTAAPTTASTANPGSTASPGSTAEPGSTAEPGSTAEPGSTASPGSTVTP--GSTASTSEPGTTASPEKIDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSLNLNISSVSIMNTG-SDTLEILETT-----VDAVREFLIFQLNEPLTKGR---TVRLHIGFEGSMANKIVGLYSSSYVKEDETR--KWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVDSSVSQG--AFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDE-ATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVD--AVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQTVENP-----DQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNE---YKYSTAETGNFFTEIDKLE-LGYNVTEIMLTWTVQMGLPVVTIEKVSDT---EYKLTQKRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWFYHDQSEITVT--VPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALAD---STQLPYATAFELTRYLDKETDYVP---WSVAASRLTSLKRTLYYT-STYAKYKKYATALIEPIYTALTWTVGED-HLDNRLRVTALSAACSLGLE--SCLTEAGEQFNAWLAKPEDRPKADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLAWN-EEYVRGQDYFTCLTYISANPVGESLVWDYVREN----------------------WQRLVDRFGLNERYLGNLIPSITARFSTQTK---LEEMEQFFAKYPE--------AGAGTAARVRALETVKNNIVWLAENLEGVDAWLD--KQPL-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFW9-1", "uniprot_id": "Q9VFW9_DROME", "id": "Q9VFW9-1", "name": "Aminopeptidase", "aln": "-------------------MFLSGYWLQVVLSWAVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWS--------------------------------------------GESRTR--MKREDTT-----------DYRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNRE-VEKFELEEE----------RQFLIITLTEELAVDA---SITLGIIFGGQMKDKLVGLYSSTYLNEAGAT--RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSG-SYHAVSNMQQTESNYLG--DYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDP-SYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVN--AVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESP-----DEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVK---HQFNNTVTDDFLTEVEAVV-TDLDIKKLMLTWTEQMGYPVLNVSKVADG---SFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFAD-DGSENSFIYDYDVDSVGIA--VPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALAD---ANQLSYKIPLDMTAYLAQERDFVP---WYVASNKLRSLHRSLMFS-EGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNRLRVSILTAACALGVP--DCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQ----------------------WPQLTTRFGLNNRNFGRLIAQITANFASSVK---LEEVQHFFSKYPE--------SGAGANSRLEAVETIKYNIEWLSRNEADITDWLSGTASPLTKKNQL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INH6-1", "uniprot_id": "Q8INH6_DROME", "id": "Q8INH6-1", "name": "glutamyl aminopeptidase", "aln": "MYAAKNVRPRSSLSTDDNHRIKDTNRPHKARSNTILTLAAFCVFLLVLCGFLLGALVYVGKNIAEEHQRQQHANASQWALNSTIRTVYVDRDQLLSTKPIISVLSDNRFYTTQVPTSKKSSIMATVAPAVKAASKVLQNLGFRLPKQIKPSKYRLHLRPDLERKNYSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLD-ESGAPLKDITPTLTFAHPEFEYWVTEFEQPLEAG----NYSLLLNFTGSLVDRITGMYQSSYLDKLKNRS-RSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVASEYVDG--DITEVTFAETVPMSTYLAAFVVSDFQYKETTVEG----TSIALKVYAPPAQVEKTQYALDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDE-STSSSVNKQRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVK--QMHPEWDMDNQFVIEELHPVLTIDATLASHPIVKSIESP-----AEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVR---HIYSTATTEDYLTAVEEEEGLEFDVKQIMQTWTEQMGLPVVEVEKSGS----TYKLTQKRFLANEDDYAAEAEASSFNYRWSIPITYTSSINSEVQSLIFNHNDNEATIT--LPEEASWIKINTNQVGYYRVNYGSEQWAELISALKNSRETFSTADRAHLLNDANTLAA---AGQLNYSVALDLISYLESEQDYVP---WSVGTSALATLRNRVYYT-DLYTNYTTYARKLLTPIVEKVTFTVAAD-HLENRLRIKVLSSACSLGHE--SSLQQAVTLFNQWLASPETRPNPDIRDVVYYYGLQQVNTEAAWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWLLQRYINWAWD-ESNVRRQDYFTLLGYISTNPVGQSLVWDYVREN----------------------WEKLVDRFGINERTLGRLIPTITARFSTETK---LEEMQQFFAKYPE--------AGAGTAARQQALEAVKANIKWLAANKAQVGEWLANYVQQSSVTNRIQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16406-1", "uniprot_id": "AMPE_MOUSE", "id": "P16406-1", "name": "Glutamyl aminopeptidase", "aln": "---------------------MNFAEEEPSKKYCIKGKHVAIICGVVVAVGLIVGLSVGLTRSCEQ------------------------------------DTTPAPSQPPPEAS--TALPPQDQNVCPDSEDESGEWKNFRLPDFINPVHYDLEVKALMEEDRYTGIVTISVNLSKPTRDLWLHIRETKITKLPELRR--PSGEQ-VPIRR--CFEYKKQEYVVIQAAEDLAATSGDSVYRLTMEFKGWLNGSLVGFYKTTYMEDGQIR---SIAATDHEPTDARKSFPCFDEPNKKSTYSISIIHPKE--YSALSNMPEEKSEMVDD-NWKKTTFVKSVPMSTYLVCFAVHRFTAIERKSRS-----GKPLKVYVQPNQKETAEYAANITQAVFDYFEDYFAMEYALPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDP-LLSASSNQQRVASVVAHELVHQWFGNTVTMDWWDDLWLNEGFASFFEFLGVN--HAEKDWQMLSQVLLEDVFPVQEDDSLMSSHPVVVTVSTP-----AEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLKK---FQFANAKTSDFWDSLQEAS--NLPVKEVMDTWTSQMGYPVVTVSGRQ-------NITQKRFLLDSKADPSQP-PSELGYTWNIPVRWADN-DNSRITVYNRLDKGGITLN-ANLSGDAFLKINPDHIGFYRVNYEGGTWDWIAEALSSNHTRFSAADRSSFIDDAFALAR---AQLLNYKIALNLTMYLKSEEDFLP---WERVISSVSYIISMFEDDRELYPMIETYFQGQVKPVADLLGWQDTGS-HITKLLRASILGFACKMGDR--EALGNASQLFDSWLKGSA-SIPVNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVKLLARYLEMLKD-PNIIKTQDVFTVIRYISYNSYGKTMAWNWIQLN----------------------WDYLVSRFTINDRYLGRIVT-IAEPFNTELQ---LWQMQSFFAKYPN--------AGAGAKPREQVLETVKNNIEWLNVNRQSIREWFASLP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50123-1", "uniprot_id": "AMPE_RAT", "id": "P50123-1", "name": "Glutamyl aminopeptidase", "aln": "---------------------MNFAEEEPSKKYCIKGKHVAIICATVVAVGLIVGLSVGLTRSCEP------------------------------------GTTPAPSNPPPHTS--TALPPQDQNVCPDSDDESGEWKNFRLPDFIQPVHYDLEVKVLMEEDRYTGIVSISVNLSKDTRDLWLHIRETRITKLPELRR--PSGEQ-VPIRR--CFEYKKQEYVVIQAEEDLAATSGDSVYRLTIEFEGWLNGSLVGFYRTTYTEDGQTK---SIAATDHEPTDARKSFPCFDEPNKKATYNISLIHPKE--YSALSNMPVEKKETLDN-DWKKTTFMKSVPMSTYLVCFAVHQFTSIQRTSRS-----GKPLTVYVQPNQKQTAEYAANITKAVFDFFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDP-LLSASSNQQRVASVVAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEFLGVN--HAEADWQMLSQVLLEDVLPVQEDDSLMSSHPVVVTVSTP-----AEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLEN---FKFKNAKTSDFWDSLEKAS--NQPVKEVMDTWTSQMGYPVVTVSGKQ-------NVTQKRFLLDYKADPSQP-PSALGYTWNIPIKWTEN-GNSNITVYYRSNREGITLN-ANLSGDGFLKINPDHIGFYRVNYEAETWDWIAETLSSNHMNFSSADRSSFIDDAFALAR---AQLLDYEKALNLTRYLTSEKDFLP---WERVISAVSYIISMFEDDRELYPLIETYFRSQVKPIADSLGWQDTGS-HITKLLRASVLGFACKMGAG--EALGNASQLFEAWLKGNE-SIPVNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVTLLARYLEMLKD-PNIIKTQDVFTVIRYISYNSYGKSMAWNWIQLN----------------------WDYLVNRFTINDRYLGRIVT-IAEPFNTELQ---LWQMQSFFAKYPN--------AGAGAKPREQVLETVKNNIEWLKLNRKSISEWFTSMP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07075-1", "uniprot_id": "AMPE_HUMAN", "id": "Q07075-1", "name": "Glutamyl aminopeptidase", "aln": "---------------------MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGG------------------------------PGTAPAPSHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKR--PSGDQ-VQVRR--CFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVK---SIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKE--YGALSNMPVAKEESVDD-KWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNS-----GKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDP-KESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVN--HAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTP-----DEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEK---YQFKNAKTSDFWAALEEAS--RLPVKEVMDTWTRQMGYPVLNVNGVK-------NITQKRFLLDPRANPSQP-PSDLGYTWNIPVKWTED-NITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALAR---AQLLDYKVALNLTKYLKREENFLP---WQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGD-HVTKLLRSSVLGFACKMGDR--EALNNASSLFEQWLNGTV-SLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKD-TNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLN----------------------WDYLVNRYTLNNRNLGRIVT-IAEPFNTELQ---LWQMESFFAKYPQ--------AGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JIB4-1", "uniprot_id": "B8JIB4_DANRE", "id": "B8JIB4-1", "name": "Aminopeptidase", "aln": "--------------------MESLDFEKKEKRYCIRGKHAAIICAVIVVTGVAVGLGVGLSLNSSSE-----------------------------------KETPLPTPLPTEVP--------DDRPCKPSENTNGGWSNFRLPDYILPFHYDLHMEPDLNTDIYTGDVSVHLKLTQPSQHLWLHIRDTFVTVMPSLQRSSPSGVTSVKLKQ--CFEYKPQEYVVVEAAEQLSVTGPDEHYVLTLHFQGWLNGSLVGFYRTTYQENGVTK---KIAATDHEPTDARKSFPCFDEPNKKATYTISITHDST--YKALSNMPVEKTEKLSE-QKTKTSFMKSVKMSTYLVCFAVHQFDFVERTSKR-----GIPLRIYAQPLQISTAAYAADVTQVIFDYFEEYFDMEYSIQKLDKIAIPDFGTGAMENWGLITYRETNLLFDE-KESSSVNKQRVASVIAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEYIGVE--EAEHDWGMRDVMLINDVYPVMVDDALLSSHPIIVDVSSP-----AEITSVFDAISYNKGASILRMLEDLLGRETFRDGCRRYLKT---YLFQNAKTSDFWKALADES--GLPVADIMDTWTKQMGYPVLSLTNTDT----EAKLTQTRFLLDPNADPSQP-TTPLGYKWTIPVKWKAL-DSTNNSFIFEKGQTEAVISGYSHATNGLIKVNKDHMGFYRVNHHDQMWSDIAEQLLMDHQVYDATDRSSYIDDIFALGR---ADMVDYGNAFNLTRYLADETEYIV---WDRVSASISYVREMLADDTVLYPLFQKLFRGHVQKISRELGWKDEGN-QTQRLLREIVLGIACQMGDQ--EALDQASDIFNKWIKGTIGSVPVNLRLLVYRYGMMNSGTEESWEIMFQKYLSATLAQEKDKLLYGLASVKNIHLLHRLLEATKN-ESIIRSQDVFTLVQYVSRSSDGKIMAWDWMTLN----------------------WDYLVNRYTINDRNLGRLPARITTTYSSNLQ---LWKMEHFFALHPN--------AGAGEMPRKQALETVKNNIEWVERNKDEIRFWLENNVS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40462-1", "uniprot_id": "TM108_YEAST", "id": "P40462-1", "name": "Protein TMA108", "aln": "-----------------------------------MSDNLLSLENPVVPSHYELRLEIDPKQ--------------------------------------------------------------------------------SSPNFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHS-KDLIVLSAHATIGSTKFDLKISQDTGKHLSIFNS--------ESPIQLSNDCPLILS---VQYVGKIRDIKTHHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQ--YKAVSNTPVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEG-DRTIPVSIYAP-WDIANAAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKFLK-SQNITNFVSSWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQ---LEDVPYQVPLFGVLPDGKMDTKNVLLTDRT-------LKFDYPILVINHLAQGYYRVSYESEECYALINDKITEETLSEIDLRKIFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDRASLTSSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLFLNKNSAKCAELCQIYFKHLLQGPRSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQNSSETAMLIQNGAIESLGFCLDSDIVKKTLNFITSNIESEGMELALFGFNYNFKKRLNKNEKPQDQVVRETIWEWYMGNFDQWARKATRKGTTTGDHLHKALRSISLIIFQMFVADEPQKIEKFINLEKEKLGQSLLSLDDIWASVQQDEESRKTIRRDLASLV----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * . * . : : : : . . * : . *:: :.: . : ::. :* * : ***:*** *: : :.: * .:** . . * : *:* : : : : . .: *. : .. : .*: *.: *** :* : ***::*::* : . ** : :: :.**:.* *:** :::. *:.**:**.** :. :. .: . : : .. *. . : : : : ** :* ** ::* *: :... : . .. . : : : ..: :** * **: : ::** **: : . : :*: . : .* *:***.: : . * :: :. : :.: :: : * : : : : : : : . . : . :. .. . *. : :: : . *. . : : . ::: : . : : . : ::: . .: : : * .: * . . . : * .: *.: *: :: : .: : : ", "identical_positions": 79, "similar_positions": 204, "identity": "7.19%" }, { "cls_id": "homologset.agr.HGNC:33550", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M575-1", "uniprot_id": "F1M575_RAT", "id": "F1M575-1", "name": "Nuclear GTPase SLIP-GC", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEETEALEGAIPHSADCELFKEPVKKRRRSH--------HDWKFQAFPSAEQSALKEYEKLECRTRRVLSN-----------------TYQKLIQSVFLDDSIPSG------LKYLIN-----------RLLALIEKPPLEPVYVGFLG----------ITGAGKSSLINALIQQAMFLPVSGESVCTSCIVQVSSGCCEQYEAKIHLLSDQEWK------------AELKDLTKLLHRAEWS---------------------------------------------------------GEEEAETWDRDDAAAEAARKLQMLYGHGADRKHYEDLLRMKPRGRIPTSRTITLK-AEEAGELSVKLDPFIRTQRRDWDGESAETPIWPLIKYVEVILPKSSLIPEGVVLVDIPGTGDFNSKRDEMWKKTIDKCSMIWVISDIERVSGGKAHEDLLSESIKACQRG-FCRDIALVVTKTDKLHLQEYLRERKMGNQAIQSQREAVLQRNEIIKLQRNKILKEKLKRKLPADSKVLEASDLVYTVSAHEYWQQALLTEE-ESEIPKLREYIRKRLLDKKRRLVTKYVTEAFGLLLLTDTFNSEENLLTEQLNMGGLR---QFVEEKMELLEKAIEQCFARIEQPLRTGVQVARASYRRILGACLVRSRGNQGFHQTLKAVCLKNGVYASR-TLARIDLNEALSQPIYDQIDPVFGGIFRDGKPTAPALMQHIDAFKQSLEKRMAEIGVRSGWKHDGYKRSFLIQEISAILGSLESHILRRKRKIYESVTSSIQNDLKPCYEEAAQITGKKACERMKDAIRRGVERQVAEGLFERAQERMWHQFRQLKPGITEKVKGSITTMLTLAAPQGDGLYKELADVRNEQKEMEKLHRSLREVAENAQLRRGMQDFLLRMSPSKAGPHGTKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YWJ0-1", "uniprot_id": "SLIP_MOUSE", "id": "D3YWJ0-1", "name": "Nuclear GTPase SLIP-GC", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEMEALVGVVPHSADCDLFKEPVRKRRRLH--------RDRQFQAFPSAEQSALKEYEKLECRTRRVLSN-----------------TYQKLIQSVFLDDSIPSG------LKYLIN-----------RLLALIEKSPLEPVYVGFLG----------ITGAGKSSLINALIRQAMFLPVSGESVCTSCIVQVSSGCCEQYEAKIHLLSDQEWK------------AELKDLTKLLHRAEQS---------------------------------------------------------GEEEADLWDRDDATEEAAQKLRMLYGHGAERRHYEELLRLKPRGRIPNSRTITLK-AEEAGELSVKLDPYIRTRRRDWDGESAETQIWPLIKYVEVILPKSALIPEGVVLVDIPGTGDFNSKRDKMWKKTIDKCSVIWVISDIERVSGGKTHEDLLSESIKACQRG-FCRDIALVVTKTDKLHLQEYLRERKMGNQAIQSQREAVLQRNEIIKLQRKRMLKEKLKRKLPADSKVLEASDLVYTVSAHEYWQRTILTEE-ESEIPKLREYIRKRILDKKRRLVTKYVTEAFGLLLLTDTLNTEESLLTEELNTGGLR---QFVEEKMELLEKAIEQCFARMEQPLQTGVQVAMTSYRRILGSCLVRSRGNQGFHQTLKAVCLKNGVYASR-TLARIDLNEALSQPIYDQIDPVFGGIFRDGKPTAPALMQHIDAFKHSLEERMAEVGVRSGWKQDGYKRSFLIQEISAILGGLESHILRRKRKIYKSVTSSIQNDLKPCYEEAAQITGKKACERMKDVIRRGVERQVAEGLFERAQERMWHQFRQLKHGITEKVKGSITTMLTLAAPQGVGLCKELADVRNEQKEMEKLYRSLREVAENAQLRRSMQDFLLRMSPSKAGPHGTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CJ6-1", "uniprot_id": "SLIP_HUMAN", "id": "Q68CJ6-1", "name": "Nuclear GTPase SLIP-GC", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAETKDVFGQEPHPVEDDLYKERTRKRRKSD--------RDQRFRAFPSMEQSALKEYEKLESRTRRVLSN-----------------TYQKLIQSVFLDDSIPNG------VKYLIN-----------RLLALIEKPTVDPIYIALFG----------STGAGKSSLINAIIQQAMFLPVSGESICTSCIVQVSSGCCVQYEAKIHLLSDQEWR------------EELKNLTKLLHRTEEL---------------------------------------------------------SREEADAWNRDEAVEEATWKLQMIYGNGAESKNYEELLRAKPKRKIPTSRVITLK-AEEAEELSIKLDPYIRTQRRDWDGEAAEMRIWPLIKHVEVTLPKSDLIPEGVVLVDIPGTGDFNSKRDEMWKKTIDKCSVIWVISDIERVSGGQAHEDLLNESIKACQRG-FCRDVALVVTKMDKLHLPEYLRERKAGNQAIQSQREAVLERNEMIKLQRTRILKEKLKRKLPADFKVLEASDLVYTVSAQEYWQQALLTEE-ETEIPKLREYIRKSLLDKKKRTVTKYVTEAFGLLLLTDSFNSTQNLPNEHLHMSVLR---RFAEEKVELLEKAIAQCFACMEQPLQEGVRTARTSYRCILRACLVRSKGNQGFHQTLKAVCLKNGIYASR-TLARIDLNEALTQPVYDQIDPVFGSIFRTGKPTGSALMPHIDAFKQSLQEKMTEIGIRSGWKYDSCKKNFLIQEISAILGGLEDHILRRKRRIYESLTASVQSDLKLCYEEAAQITGKKACERMKDAIRRGVDRQVAEGMFERAQERMQHQFQQLKTGIVEKVKGSITTMLALASSQGDGLYKELADVGSEYKEMEKLHRSLREVAENARLRKGMQEFLLRASPSKAGPPGTSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HWZ3-1", "uniprot_id": "A0AC58HWZ3_DANRE", "id": "A0AC58HWZ3-1", "name": "", "aln": "MDSHTINFITWNINGLKQNKYQKFQELQCADVVFLQETHIGAGDEHVIEGLKDEWNVFYTKYNSSSSGTAILVRKSLDFKCLSVEKGHCGEYVLLKCELEGCLYTLVSVYNHQTDTKTLDNLSRYLQSMTTGLLVIGGDFNTFLNPFIDKKCTGKMTKNRMHNKLILCVENFMESLQLADVWRRMNPVKQDFTFYIRDRPVSRLDYFFIPDECMWRVGSCEIMNFGELKDHQPVSLEINSVYFTAKKQFHCKNILLTDETSSSQSEESSPGVSEVDIVSAVQSLQVSDTVRPDDIPVSSYKDNIRDVIPHIKMLYGKIHRGEVNCPELYFQDPQDDIPHFLNADYLIIATILARRLNYLLNPQSKGTIKDTAIVMITPKTVCTEAMLCCLKDEIEDSHSVLYQDFQLVEKILRDSKFKKCQGCPLKPVLTALKLKSCALKLCKNLENYAVHVFKTNVIICVPSEDLDEILAMESSNNEEYDIMTLYRGQSVEGNESASEDYDGLLEDTEDNSQCEDSDNGSNEHEGKSKSIESDGRTTMYAVVTLEKSEEVMVTASNWLSEGKKQCYWPPYKSSEKLMEAVQKGLAPQTGEKSWEKLAVLFHGEYGTYEEANKKRKEMNEQTEQAATAVNQVTGTCPQSPGPSQSGISQNASGTKRKRESRDLLISAKSYSDIEILNIAKKIMNEVDDRLRNITSTDQKTNEIKNTILDSIAKMKEMDKDKRRKETIGVFGKTGEGKSSLLNAVLGLEGLLPSGSLGACTAVITQVEANLEDSKYIAEIELISKEEWENEIASTDERTDTDNERIIAVYGADADKKSLEELKKDAKYAEIDQFLSIGKKTISHSEVLDFDLDVKCHIQQSEYS---PGGWYWPLVKSVTIKIPDRQELLEHIVLFDIPGTGDCNKIRNDLWKSKVRECSSVWIVNGISRAISSIEPWSIMEHCMQDLGPGGQCKTINFICTRTDDINIKEYQRSALPSGDQFTSGKNLKTACIHHRNKTAKDSVKNKFETMKSKDFRRFTAD--VFTVSSKAYFDADLQMDQNETEIPKLQDLLKNTNKSIRRELIRDYVNQAKGVLFFIQSIKLDTNEGMAKLKATVCKDYYESLEKALKELNSRFDSHYKIIEQCFSKGVEKSVEQCVSTTKPVIASVKPSD---KTLQALCKNKGYYWPKSKDAAVDLNKCLAKHIYDNIDEEFNLIFPVDSKIKTGKSVQEQIDKFSIIQNGTVYPPSS---MLYHIQNFMKTEETKVKTFLKRDVVHRKKKIYSSIQTTIQDQMTAGYKKAAEKKGVGAMGRRETTIIETIELLKDS-MFKDTKIQFLKEFKSVTSDICERLKSELSRSVERSFSQSS--KASLMDVSKEIETLETLSEHIAEI-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 143, "similar_positions": 307, "identity": "10.16%" }, { "cls_id": "homologset.agr.HGNC:33551", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AMZ4-1", "uniprot_id": "NDUF8_MOUSE", "id": "A2AMZ4-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8", "aln": "MSVNGAVWGRVRSRFRAFPEHLAACGAEASAYGKCVQASTAPGGRLSKDLCVREFEALRSCFAAAAKKT-----MMG---GS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M8P4-1", "uniprot_id": "A0ABK0M8P4_RAT", "id": "A0ABK0M8P4-1", "name": "", "aln": "MSVNGAVWGRVRSRLRAFPEHLAACGAEASAYGKCVQASTAPGGRLSKDLCVREFEALRSCFAAAVGQEDHDGRLLGRAMGTDALY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1L188-1", "uniprot_id": "NDUF8_HUMAN", "id": "A1L188-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8", "aln": "MSANGAVWGRVRSRLRAFPERLAACGAEAAAYGRCVQASTAPGGRLSKDFCAREFEALRSCFAAAAKKT-----LEG---GC----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "U3JA56-1", "uniprot_id": "U3JA56_DANRE", "id": "U3JA56-1", "name": "", "aln": "MSGS-NVWTRSRARMRLFPELMAQCSGEATAYGKCVAATTTGKQELTRNMCVKEFEALKSCFQSAAKKA-----VK----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . ** * *:*:* *** :* *..**:***:** *:*: .*::::*.:*****:*** :*. : : ", "identical_positions": 33, "similar_positions": 22, "identity": "38.37%" }, { "cls_id": "homologset.agr.HGNC:3356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06802-1", "uniprot_id": "ENPP1_MOUSE", "id": "P06802-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "aln": "MERD--------GDQAGHGPRHGSAGNGRE------LESP----AAASLLAPMDLGEEPLEKAERARPAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKLKNCG----TYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTAN-----HQEVKSGTYFWPGSDVEID-----------------GILPDIYKVYNGSVPFEERILAVLEWLQLPSH-ERPHFYTLYLEEPDSSGHSHGP------VSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKK--YVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQ-------HFRPYLKPFLPKRLHFAKSDR--------IEPLTFYLDPQWQLALNPSERKYCGS-------------GFHGSD-NLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSND-LGCTCDPWIVPIKDFEKQLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLRNDQFSRDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924C3-1", "uniprot_id": "ENPP1_RAT", "id": "Q924C3-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "aln": "MERD--------GEQAGQGPRHGPAGNGRE------LESP----AAASLLAPMDLGEEPLEKAERARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVCSCADDCKAHNDCCINYSSVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKLKNCG----TYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTAN-----HQEVRSGTYFWPGSDVEID-----------------GILPDIYKVYNGSVPFEERILAVLEWLQLPSY-ERPHFYTLYLEEPDSSGHSHGP------VSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKK--YVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYSFNYEALAKNLSCRETNQ-------HFRPYLKHFLPKRLHFAKNDR--------IEPLTFYLDPQWQLALNPSERKYCGS-------------GFHGSD-NLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNESHGSLNHLLKKPIYTPSHPKEESFLSQCPIKSVSSD-LGCTCDPSIVPIMDFEKQFNLTTDAVEDVYSMTVPNGRPRNLQKQHRVCLLHQQQFLTGYSLDLLMPLWTSYTFLSNDQFSTDDFSNCLYQDLRIPLSPMHKCSYYKSTSKLSYGFLTPPRLNRVSRQIYSEALLTSNIVPMYQSFQVIWQYLHDTVLRRYAQERNGVNVVSGPVFDFDYDGRYDSSEILKQNTRVIRSQENLIPTHFFIVLTSCKQLSESPLKCTALESSAFLLPHRPDNIESCTHGKQESAWVEELLALHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22413-1", "uniprot_id": "ENPP1_HUMAN", "id": "P22413-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "aln": "MERDGCAGGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPLEKAARARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGG-LLPVISKLKKCG----TYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAK-----YQGLKSGTFFWPGSDVEIN-----------------GIFPDIYKMYNGSVPFEERILAVLQWLQLPKD-ERPHFYTLYLEEPDSSGHSYGP------VSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKK--YIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQ-------HFKPYLKHFLPKRLHFAKSDR--------IEPLTFYLDPQWQLALNPSERKYCGS-------------GFHGSD-NVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTFSQED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "---------------MELQNDLESLDNELN-----------------------DFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTN-NPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKV-PFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSH--FGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED-------KYTVYVNGNFPKEWNFNDGKN------HHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQ-GYIEPFQNTEIYNLLCDICGVAEKDRNSNDGTG--MLMNQLREPQSSEEV----------------------------EIEDDFDYLVSKFGEFSTYNIIWGG-YPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "--------------------------------------------------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK--------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDN--GPRTIANRSNTYFNGTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSN-TADPIWQLLQTESQG--EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIPNVDSYGHSFGYDLRD----KRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNN-EVVPPFENIEVYNMLIKASALLGEEKTKKEKS----LLQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :. : :: . * : * : . .. . : : . *:::*:***:. : :* : :*: * : * * :**:*****:::*** ** ***:.* ::* . .* : :*** : : .*.:****:* * : :* :.::: ::.::::. :**.: *: : *: **..* . . : : .** :. *::.*:. .* *::::*****.: . : : : : . . . * . : : : :. : :: :: : :: . .. : : : : : : . . . * ** : * :* ::*:* ** * : .*:* *:**:: . : .. .. : * : ", "identical_positions": 76, "similar_positions": 143, "identity": "7.68%" }, { "cls_id": "homologset.agr.HGNC:3357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1E6-1", "uniprot_id": "ENPP2_MOUSE", "id": "Q9R1E6-1", "name": "Autotaxin", "aln": "--MARQGCFGSYQVISLFTFAIGVNLCLGFTASRIKRAE-WDEGPPTVLSD-SPWTN----TSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCG----THAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLEELNKR----LHTKGSTE-------------------------ERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYESEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64610-1", "uniprot_id": "ENPP2_RAT", "id": "Q64610-1", "name": "Autotaxin", "aln": "--MARQGCLGSFQVISLFTFAISVNICLGFTASRIKRAE-WDEGPPTVLSD-SPWTN----TSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCG----THAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPKTIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPDEVSRPNYPGIMYLQSEFDLGCTCDDKVEPKNKLEELNKR----LHTKGSTEAETGKFRGSKHENKKNLNGSVEPRKERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWAYFQRVLVKKYASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYESEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13822-1", "uniprot_id": "ENPP2_HUMAN", "id": "Q13822-1", "name": "Autotaxin", "aln": "--MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSD-SPWTN----ISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCG----THSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKR----LHTKGSTE-------------------------ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HF17-1", "uniprot_id": "A0AC58HF17_DANRE", "id": "A0AC58HF17-1", "name": "", "aln": "--MSNMDFIEVFSVLWLFS---RLTVCKTYVVRRSGKAASPDESLSKSFSD-HPFTS----LAGSCKKRCFELVEADPPNCRCDNLCKTYNMCCSDFDDHCLKTAGGFECSKERCGENRNEQHACHCSEDCMAKGDCCTNYRSLCKGDVPWLQEECEEIKNHECPAGFVRPPVIMLSVDGFRASYMK-RGGTVIPNIEKLRSCG----THAPYMRPMYPTKTYPNLYTITTGLYPESHGIVGNSIHDPSFDANFNFRGKEKLNHRWWGGQPIWITAMKQGVKAGSFFWPVAIPMERRVLTMLQWLHLPDAERPYLYAMHSEQLDSYGHKLGPHSTELNSALRDVDKVIGQLMNGLKQMKLHRCINIILVGDHGMEEAHCDKTEFLSSYMSNTEDLILIPGSLGRIRARNPNNSKFDAKAVVANLTCKKPDQHFKPYLKQHLPKRLHYANNDRIEEIHLMVERKWHIARKIMKTKRN-HEKCGFAGDHGYDNKINSMQTIFLGYGPAFKFKTKIPPFENIELYNIMCDLLGLKPAPNNGTHGSLNQLLRTPVYIPNMPEEVTKPNPAGPVIAIND-DLGCTCEDKVSNKLRSKSRGKRALKVTLVRGYNVESLWLCLLQNKVDELNQRLRQVIDDNKNLPYGRPAVMFRTKYCILHHTDYISGYSEALHMPLWTSYTVSKQVDFTPLTDALSNCIRPDSRVPTAYSQSCSNYRTEKQISYSFLYPPQLSSTQEARYDAVLITNTVPMYTAFKRVWSYFQKSLVKRYASEKNGVNVVTGPIFDYDYNGLRDSAETIKQFVSG-SVQIPTHYFVVVTSCLDYTQTVDSCVGPLSVFSFILPHRSDNEETCNSSEDESKWVEELMKTHTARLRDVELLTGLDFYRRTSRTYEEILALKTYLHTYESEI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGF---HSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGD----------IPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLN------------------ERPQLILGYVPNVDAFGHKHG--------------YPSESEYYYEDFTETLGEVDTFLKQLVES-LQERNLTSFTN-------------------------LVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED---------------KYTVYVNGNFPKEWNFNDGKN------HHMAS-------------------------------------IWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQGYIEP---------FQNTEIYNLLCDICGVAEKDRNSNDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK----------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDNGPRTIANRSNTYFNGTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSN-TADPIWQLLQTESQG------------EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLK------------------DRPELVISYIPNVDSYGHSFG--------------YDLRD----KRLQKLIGEVDGFFLDLIEG-LQKRNLLKISN-------------------------VMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGD--------EISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGD-------------------------------------IWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNNEVVPP---------FENIEVYNMLIKASALLGEEKTKKEKS--LLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : :: : . : :: : : : . . *::*:***:. :. : .: :: :*: * :*:* * :**:*:** :::.** ** ****.* : * . *. : :*:* . : * : :: *. . . :.. :.::: :. *: ::.::: .*:.*.: * : . : ... :: : : *: * : : : .*** .: .: : : ..: . * : .. : :: : : : . : . : *:: : .* .: :. .: : . . :.. : . . . : : : ", "identical_positions": 42, "similar_positions": 137, "identity": "4.65%" }, { "cls_id": "homologset.agr.HGNC:33577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P37297-1", "uniprot_id": "STT4_YEAST", "id": "P37297-1", "name": "Phosphatidylinositol 4-kinase STT4", "aln": "MRFTRGLKASSSLRAKAIGRLTKLSTGAPNDQNSNGTTLDLITHTLPIFYSTNTSKIYTIPLTLSEWEVLTSLCVAIPTTLDLVETMLKEIIAPYFLETPRQRISDVLSSKFKLEQMRNPIELLTFQLTKFMIQACEQYPVLYENIGGIISTYFERVLKIFTIKQSGLLSLVGFINAFIQFPNSTELTKFTWKKLAKLVLRGSFLNEVDKILNSSATFTNDSIVQYYDAGNELSSAYLLELISRLQVSLISHLLNTSHVGANLSEFLLNQQYQFYKFDQEVADENDDTKCIDDFFFNVRSNKQFFTDMCKISLQFCSESHILDLSTDNRARFSFDTRAHYLQTLCLIPFIEDTESELFESFTNVVSESIDKFFLSDVVTPSLIKAIVASASLLNFFTEKLSLTLIRMFPLLVASPHITTETVNDVAKIFTTGLYPLNEDAIVSTIYSMNNLLAVSEDGSPVPVLRERQLTITSGKNIEKDYFPLRNSSASLDGTGALLGNTTVGQLSSHDVNSGATMTYHASLISNCVAATTTIASYYNTQSITALTISILTQKVNSMSKELDGVILNSLARLAPNTSLTEFSLLLKFFKSRTVIATKIDDSALLKNIIKAKCVISKELLARHFSSDLYFMYLHDLLDSIIASGEVERLEHHRPQTEISRVADQIATYLEPLAALLPVPGDTPLDINKDEVTTNKFRNAWFNFVIHGYHLGGPIVKRNFSFLLTIAYNSPPLASEFPANNKELSLEMNTILRRGSSNENIKQQKQQITEYFNTNIVQYRTTSSSKIMFLAAAVLLETIRCEAGDCSKTLLYFSDPSILSGSIEKCIAVLSVSMIRKYARLIQKGNDAIFNSKMIAQQLNNLLLCLSHREPTLQDAAFHACEIFIRSIPSSLCHHLSLYTLLDMLTALFDSILDSEAHKFEPRYEFKLKHSKTTILVPSSSSWRATTLSRLHKSAKEWVRILLNRSNQDTKILLQSYISDLGEYSRLNSVEFGVSFAMDMAGLILPADKELSRLTYYGPEKPNTISGFISLHSWRSKYLFDTAITSSPEDIKRQIGISTQNIRKNLTLGNKIITKDVTDFLDMATALLILGNGAPASLIYDIVHIPFEVFTSASLKIATNVWLTIITEKPEVAHLLLVEVCYCWMRSIDDNIGLYSRDHDLKGEEYQKMEYSPYDKAGINRDAKNASQAMQPHLHVIKFFASHFEGTLFQSDFLLKIFTKCALYGIKNLYKASLHPFARMIRHELLLFATLVLNASYKQGSKYMGRLSQEITNGALSWFKRPVAWPFGSNELKIKADLSVTRDLFLQLNKLSSLMSRHCGKDYKILNYFLASEIQQIQTWLTPTEKIEGADSNELTSDIVEATFAKDPTLAINLLQRCYSKKAEDVLVGLVAKHALMCVGSPSALDLFIKGSHLSSKKDLHATLYWAPVSPLKSINLFLPEWQGNSFILQFSIYSLESQDVNLAFFYVPQIVQCLRYDKTGYVERLILDTAKISVLFSHQIIWNMLANCYKDDEGIQEDEIKPTLDRIRERMVSSFSQSHRDFYEREFEFFDEVTGISGKLKPYIKKSKAEKKHKIDEEMSKIEVKPDVYLPSNPDGVVIDIDRKSGKPLQSHAKAPFMATFKIKKDVKDPLTGK-----------------NKEVEKWQAAIFKVGDDCR--------------------QDVLALQLISLFRTIWSSIGLDVYVFPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYEYFTSKFGNESTIEFQNARNNFVKSLAGYSVISYLLQFKDRHNGNIMYDDQGHCLHIDFGFIFDIVPGGIKFEAVPFKLTKEMVKVMGGSPQTPAYLDFEELCIKAYLAAR---PHVEAIIECVNPMLGSGLPCFKGHKTIRNLRARFQPQKTDHEAALYMKALIRKSYESIFTKGYDEFQRLTNGIPY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A4QPH2-1", "uniprot_id": "PI4P2_HUMAN", "id": "A4QPH2-1", "name": "Putative phosphatidylinositol 4-kinase alpha-like protein P2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVEQKFGLFS----------AEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFS---------------------------------------------------------SLLQRSMSLNIGRAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQG---------EKRLREDISIMIKFWTAMFSDKKYLTASQLVP-----------------------------------------------------------------------------------------------------------------------------PADIGDLLEQLVEENTGSLSGPAKDFYQRGFDFFNKITNVSAVIKPYPKGD--ERKKACLSALSEVTVQPGCSLPSNPEAIVLDVDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKLGDDCRQKSYWGARMPTDRILRLPASQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVQATWLCGEPGPYMDVVVSLVTIMLDTGLPCFRG-QTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYNMIQYYQNDIPY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::::**:* ::: : *. :.* .. : ** *.*:..:** : : *. ::**: * ::*.:: :* : .:: .::. * *. **: . : .* * : . . ::: . *: . * : :* :: *:: :*.* . **. :* *::: *. ..*:* . :***:* *:**:::*.:*. :*** * . *:*: . :*:: *:*. *****:.:*:*:* ***.*:** ****::*.**:*: . * : : : .*******:***** **:****:*.**:.*:. :***::******.*********: :*:..*** ***:: *:*:*** ::*:***: **:** **::*:*.**:: :***:********* *.:** :******:*: *** :***.*** :***. ::..: * *:*::* . *:::.::. *. **.:*****:* :**: *: **.*: *::*** :: :*:..: * :: *: :* *.***", "identical_positions": 209, "similar_positions": 193, "identity": "10.77%" }, { "cls_id": "homologset.agr.HGNC:3358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DYE8-1", "uniprot_id": "ENPP3_MOUSE", "id": "Q6DYE8-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "aln": "---------MDSRLALATEEPIKKDSLKKYKILCVVLLALLVIVSLGLGLG-LGLRKPEEQ-GSCRKKCFDSSHRGLEGCRCDSGCTGRGDCCWDFEDTCVKSTQIWTCNLFRCGENRLETALCSCADDCLQRKDCCADYKTVCQGESPWVTEACASSQEPQCPPGFDLPPVILFSMDGFRAEYLQTWST-LLPNINKLKTCG----IHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVHLNKNFSLSSVEKSNPAWWSGQPIWLTAMY--QG---LKAACYYWPGSDVAVN-----------------GSFPTIYRNYSNSVPYERRITTLLQWLDLPKAD-RPSFYTIYVEEPDSAGHSSGPVSAG------VIKALQSVDNAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPKIN---------FYMYQGPAPRIRTRNIPQDFFTFNSEEIVRNLSCRKP-DQHFKPYLTPDLPKRLHYAKNVR--------IDKAHLMVDRQWLAFRSKGSSNCGGG--------------THGYN-NEFKSMEAIFLAHGPSFIEKTVIEPFENIEVYNLLCDLLHIEPAPNNGTHGSLNHLLKTPFYKPSHAGELSTPADCGFTTPLPTDPLDCSCPALQNTPGLEEQANQRLNLSEGEVAATVKANLPFGRPRVMQKNGDHCLLYHRDYISGYGKAMKMPMWSSYTVLKPGDTSSLPPTVPDCLRADVRVAPSESQKCSFYLADKNITHGFLYP-AIKGTNESRYDALITSNLVPMYKEFKKMWDYFHEVLLIKYAIERNGLNVVSGPIFDYNYDGHFDAPDEITQYVAGTDVPIPTHYFVVLTSCKDQTHTPDSCPGWLDVLPFIVPHRPTNIESCSENKTEDLWVEERFQAHAARVRDVELLTGLDFYQEKAQPVSQILQLKTYLPTFETII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97675-1", "uniprot_id": "ENPP3_RAT", "id": "P97675-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "aln": "---------MDSRLALATEEPIKKDSLKRYKILCAVLLALLVIVSLGLGLG-LGLRKPEEHIGSCRKKCFDSSHRGLEGCRCDSGCTDRGDCCWDFEDTCVKSTQIWTCNSFRCGETRLEAALCSCADDCLQRKDCCTDYKAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWST-LLPNINKLKTCG----LHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMY--QG---LKAASYYWPGSDVAVN-----------------GSFPNIYRNYSNSVPYESRIATLLQWLDLPKAE-RPSFYTIYVEEPDSAGHKSGPVSAG------VIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEIN---------FYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKS-DQHFKPYLTPDLPKRLHYAKNVR--------IDKVHLMVDRQWLAYRNKGSSNCEGG--------------THGYN-NEFKSMEAIFLAHGPSFKEKTVIEPFENIEVYNLLCDLLHIQPAPNNGSHGSLNHLLKAPFYQPSHAEELSKSAGCGFTTPLPKDSLNCSCLALQ-TSGQEEQVNQRLNLSGGEVSATEKTNLPFGRPRVIQKNKDHCLLYHREYVSGFGKAMKMPMWSSYTVPKPGDTSSLPPTVPDCLRADVRVDPSESQKCSFYLADQNIDHGFLYPPAIKGNNESQYDALITSNLVPMYKEFKKMWDYFHKVLLIKYAIERNGVNVVSGPIFDYNYDGHFDAPDEITNYVAGTDVPVPTHYFVVLTSCKNKTHTPDSCPGWLDVLPFVVPHRPTNVESCPENKAEDLWVEERFKAHIARVRDVELLTGLDFYQEKTQPVSEILQLKTYLPTFETII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14638-1", "uniprot_id": "ENPP3_HUMAN", "id": "O14638-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "aln": "---------MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLG-LGLRKLEKQ-GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDT-LMPNINKLKTCG----IHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMY--QG---LKAATYFWPGSEVAIN-----------------GSFPSIYMPYNGSVPFEERISTLLKWLDLPKAE-RPRFYTMYFEEPDSSGHAGGPVSAR------VIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINF--------FYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKP-DQHFKPYLTPDLPKRLHYAKNVR--------IDKVHLFVDQQWLAVRSKSNTNCGGG--------------NHGYN-NEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQ-NSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLT--IVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED-------KYTVYVNGNFPKEWNFNDGKN------HHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQG-YIEPFQNTEIYNLLCDICGVAEKDRNSNDGTG--MLMNQLREPQSSEEV--------------------------------EIEDDFDYLVSKFGEFSTYNIIWGG---YPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK-------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDNGPRTIANRSNTYFNGTHDFKTLT--ILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSN-TADPIWQLLQTESQG--EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIPNVDSYGHSFGYDLRD----KRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNNE-VVPPFENIEVYNMLIKASALLGEEKTKKEKS----LLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: * * * . . .. . *::*:***:. : * :: :: :*: : :* . :**:*****:::*** ** ***:.* ::* ..:* . : :*:* :* *.* : ****:* * : :. . ::: ::.::*:. . ** : *. : *: ** * . : : ** : *:*.*::*** . *:::::****.: : : : . :** : :: . . : : :: :. :: :: . . : . :. : : : . * .***: *: .* ::*:. ** * : : **:* *:**:: . : .. .. : * ", "identical_positions": 82, "similar_positions": 127, "identity": "8.6%" }, { "cls_id": "homologset.agr.HGNC:33584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBT3-1", "uniprot_id": "B1WBT3_RAT", "id": "B1WBT3-1", "name": "BICD family-like cargo adapter 2", "aln": "MDGTFLWQCPVIPTTRGRPSPSRSTAPSPVQACTWRRLRKRSSGIGEPRREPGGDRCVGTMDSPGGPSFSSGLLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNAQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRGQCQTQALAGAELRTRLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQGRLQTTHEELLLLRRERKEHKLELERARFEAGEALSTLRRLQRRVSELE-------------------------------------------------------EESRLQDAEISGASLQTELAHSLDSDQDQDQQVNECRASQTILSPETEEASSPQPSIQEESLEPPKKRASLSPVEILEEKEAEVARLQDEISLHRTELQSLRDELQ-RQKELRAQDNPEEALSCALSDRDEAVNKALKLSLELNRVSLERDSLSRELMRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAA----PRRSKTRFSLRLGSGQSG-GFLSNFFRRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHW5-1", "uniprot_id": "BICL2_MOUSE", "id": "Q8CHW5-1", "name": "BICD family-like cargo adapter 2", "aln": "------------------------------------------------------------MDSPGEPSFPSGLLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELE-------------------------------------------------------EESRLQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQETSSPQPSIQEEILEPPKKRASLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQ-RQKELRAQDNPEEALSSALSDRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAA----PRRAKTRFSLRLGSGQSG-GFLSNLFRRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1A5D9-1", "uniprot_id": "BICL2_HUMAN", "id": "A1A5D9-1", "name": "BICD family-like cargo adapter 2", "aln": "------------------------------------------------------------MSSPDGPSFPSGPLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLSAQHLEREERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELE-------------------------------------------------------EESRLQDADVSAASLQSELAHSLD-DGDQGQGADAPGDTPTTRSPKTRKASSPQPSPPEEILEPPKKRTSLSPAEILEEKEVEVAKLQDEISLQQAELQSLREELQ-RQKELRAQEDPGEALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSASASSST--PRRAAPRFSLRLGPGPAG-GFLSNLFRRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JMK8-1", "uniprot_id": "BICL2_DANRE", "id": "A0JMK8-1", "name": "BICD family-like cargo adapter 2", "aln": "----------------------------------------------------------------------------MAPTMGVDDLLASPQDDRS------------------PTLLEKDLILAAEVGQALLEKNEELASQIMQMES----EMEAMQQEKHMVQRRLEVRDLEASQREAELQADISALRAQLEQKHIQGRDRRREESEQLIQLSNHNQKLVEQLAEAVSLEHTLRTELRTLREEMEDTSFSKSISSARLDSLQAENRVLKERCTHMDERLKSTQEDNERLRSERDGLRERAIELQTSLKDKETELEQEHSTVFQLRTVNRTLQQRVQALG-------------------------------------------------------EEASLGEATCFPLSLQSEIQQCQA------------------------------------------KETILAHSSVLREKEEEIQRLQKELQSRETELEGLREEVK-LFR----------------NSPGKPTYKALEEEMILARQ--ERDALNQQLLNTIRHKVALSQEVESWQEDMRLVICQQVQLQQQEKEKENNKERTGFQRGTRTTKSLRLRGEEGRKGFFSALFGGD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SWR2-1", "uniprot_id": "BICDR_DROME", "id": "Q8SWR2-1", "name": "Bicaudal D-related protein homolog", "aln": "----MHKPKLANAITAAAIASSISTKNNNNNSIVGGSSSSSSGGNKSKRPRQFGQYSIGVGTGAGAGGLLRSDDSGFDHLDYSSLIGDSIDLEHYISAMEARRHDQEPDVWAQLQQKESDILLAAELGKALLEKNEELVKQQEKLIEDYSSKIEKLEQEKHVLRQKLAIAEDESDQRVLELQSDLTELKDKLQTQDTAIRQAEKEKTILIDELQHQNTRLTEQIQEAHATELKLSAQIQELKDQYHYRNSSLQEHVNSLESIKTELNLTTGKRQELERRLQIAQEEKESLTSSLEESSDRIHMLERHAREQETKLETTLQALERSQRENNVLSERLGADTNSSTPGRKSLQFEMECDEDDGSYTETGKPNQMFVEARSVYIQLKSLVDSLKVSHDDDSGLNSDISLELESMDNTISSSERHEDGHLAIEFRQGMLSSMSDELTRLLLNLDAGNFKKMLDQTRNLVLEQEDEIKRSHQLIQQLEAKVTVTDVELQNVKEERDQARGDLEDNTDRDELLSKAQTERDAANDRRTKAEVELAKTRVELMQANSQLLESIQQKVELSQQLEQWQMDMHELIDEQMRSKLINNRRAMAAESSAPSPPSSAAANLAKRVTSYK---LWSLFQR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *.*::****:*: ***:**** * : . * ::**:* ::: * * . * **:.*: *: :* : :: :*.: : :*..:* :* :*: :* * * :: *: . . : *:*:: * .: : .:: ::: :*: : . : :. *. :::. :** . . *..*: ::: * . . : . :. * . :.... : :*: :: .**: :::* . .. . . : : .: * : * . :*:.:*::** *:*::* ** **: :* :*:: : :: : . .* : :* ", "identical_positions": 68, "similar_positions": 132, "identity": "10.83%" }, { "cls_id": "homologset.agr.HGNC:3359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTJ4-1", "uniprot_id": "ENPP4_MOUSE", "id": "Q8BTJ4-1", "name": "Bis(5'-adenosyl)-triphosphatase enpp4", "aln": "---------------------------------------------------------------------------------------------------------------------------MFNMKILVIPLFWG--------------LVTGYK--GNSSDSSAPRLLLVSFDGFRADYLKSYDLPHLQNFIKEG-------VLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDSVTKKHFSESNDKDPFWWN-GAEPIWVTNQLQENR----SSAAAMWPGTDVP-----------------IHNITASYFMNYSSSVSFKERLGNVTTWLSS--SNPPVTFAALYWEEPDVSGHKYGPEDKE-----NMRRVLKEVDDLIGDIVLKLKVLGLWDSLNVIITSDHGMAQCSKNR---------LIDLDSCIDRSNYSVIDLTPVAAILP-KINVTEVYDKLKR---------CNPHMNVYLKEAIPNRFYYQHSSR--------IQPIILVAEEGWTITLNKSSFK----------------LGDHGYD-NSLPSMHPFLAAHGPAFRKGYRQSTINTVDIYPMMCHILGLKPHPNNGTLSHTKCLLVDQWCINLPEAIGIVVSALLVLTMLTGLMIFMRSR-ASTSRPFSRLQLQEDDDD-PLID------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2W1-1", "uniprot_id": "D4A2W1_RAT", "id": "D4A2W1-1", "name": "Bis(5'-adenosyl)-triphosphatase ENPP4", "aln": "---------------------------------------------------------------------------------------------------------------------------VFNMKLLVILSFWG--------------LVAGYR--GNSSYSSAPQLLLVSFDGFRADYLNNYDLPHLQNFIKEG-------VLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDDVTKKHFSESNDKDPFWWN-GAVPIWVTNQLQENR----SSAAAMWPGTDVS-----------------IHNVTPSYFMNYSSSVPFEERLNNVATWLSS--SNPPVTFATLYWEEPDVSGHKYGPEDKF-----NMRRVLKEVDGLIGDLVQKLKALGLWESLNVIITSDHGMAQCSENR---------RIYLDTCINHSDYSVIDLTPVAAILP-KINVTEVYNKLKH---------CNPHMTVYLKEAIPNRFYYQHSDR--------IQPILLVADEGWTIALNTSSSK----------------LGDHGYD-NSLPSMHPFLAAHGPAFRKGYRQSTINTVDIYPMMCYILGLKPHPNNGTFSHSKCLLVDQWCINLPEAIGIVVSALLALTVLTGLIIFMQNR-ASASRPFSRLQLHEDDDDDPLIE------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6X5-1", "uniprot_id": "ENPP4_HUMAN", "id": "Q9Y6X5-1", "name": "Bis(5'-adenosyl)-triphosphatase ENPP4", "aln": "------------------------------------------------------------------------------------------------------------------------------MKLLVILLFSG--------------LITGFR--SDSSSSLPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEG-------VLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWN-EAVPIWVTNQLQENR----SSAAAMWPGTDVP-----------------IHDTISSYFMNYNSSVSFEERLNNITMWLNN--SNPPVTFATLYWEEPDASGHKYGPEDKE-----NMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDR---------LINLDSCIDHSYYTLIDLSPVAAILP-KINRTEVYNKLKN---------CSPHMNVYLKEDIPNRFYYQHNDR--------IQPIILVADEGWTIVLNESSQK----------------LGDHGYD-NSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIAIVIGSLLVLTMLTCLIIIMQNR-LSVPRPFSRLQLQEDDDD-PLIG------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566N0-1", "uniprot_id": "ENPP4_DANRE", "id": "Q566N0-1", "name": "Bis(5'-adenosyl)-triphosphatase enpp4", "aln": "--------------------------------------------------------------------------------------------------------------------------MQISAYLCALIACCG--------------LTLSAPTANNKSSSEAPPLLLVSFDGFRADYLNKYSFPNLEKFFSDG-------VLVHELTNVFTTKTFPNHYSLVTGLYAESHGMLASIMYDPVAKKHFSIKNDSDPFWWD-EATPIWVS-VEESGY----HAASAMWPGSDVN-----------------IQNHTLKYTFKYDSRVSFKERLGNITQWMTT--DKS-LKFASLYWEEPDFSGHTYGPDNTT-----EMARVLKEVDGHVGYLMEELDRMELWGKINVIITSDHGMAQCSEER---------IIRLDDCVSPSSYTLVDLTPVAAIIP-LEDKTTVYNNLSS---------CHVHLKAYMKNDVPDRLHYKNNER--------IQPIILVADEGWTIVKNGRLPR----------------LGDHGYD-NTLPSMHPFLAAHGPAFRKGYKMSSFNSVDLYPLMCHLIGIPPKANNGSFAHVRCTLVNEQCGELALAVGLVMGVLIILTTFTCLFKLMKNRNVSSPRPFARLELDDDGDDEPLLE------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED-------KYTVYVNGNFPKEWNFNDGKN------HHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQGYIEP-FQNTEIYNLLCDICGVAEKDRNS--NDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK-------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDNGPRTIANRSNTYFNGTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSN-TADPIWQLLQTESQG--EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIPNVDSYGHSFGYDLRD----KRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNNEVVPP-FENIEVYNMLIKASALLGEEKTK--KEKS--LLQ---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . :::*:***:. :. * * .: . . . : * *:*****:::*** * **:::. ::* ...* . :* : : *** *: ****::* :: * ::. :.::* :: :: : : * : * **..* : . : ::* . :: *. * *::*.*****:: : . : : . : : : : . :. : . :: . : . .. : * ::.: ::: :* ***: *. .* ..: . ** * : . :: ::* :: .: . .. . *:: ", "identical_positions": 60, "similar_positions": 125, "identity": "7.88%" }, { "cls_id": "homologset.agr.HGNC:33593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1KXW8-1", "uniprot_id": "FA72A_RAT", "id": "A1KXW8-1", "name": "Protein FAM72A", "aln": "MSTNNCTFKDRCVSILCCKFCKQVLSSRGMKAVLLADTDIDLYSTDIPPTNTVDFIGRCYFTGIHKCKLKDIACLKCGNIVGYHVIVPCSSCLLSCNNGHFWMFHSQAVYGINRLDSTGVNFLLWGNLPETEECTDEEMLEISAEEYIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ8-1", "uniprot_id": "FA72A_MOUSE", "id": "Q8BFZ8-1", "name": "Protein FAM72A", "aln": "MSTNNCTFKDRCVSILCCKFCKQVLSSRGMKAVLLADTDIDLFSTDIPPTNTVDFIGRCYFTGICKCKLKDIACLKCGNIVGYHVIVPCSSCLLSCNNGHFWMFHSQAVYGINRLDATGVNLLLWGNLPETEECTDEETLEISAEEYIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6L9T8-1", "uniprot_id": "FA72D_HUMAN", "id": "Q6L9T8-1", "name": "Protein FAM72D", "aln": "MSTNICSFKDRCVSILCCKFCKQVLSSRGMKAVLLADTEIDLFSTDIPPTNAVDFTGRCYFTKICKCKLKDIACLKCGNIVGYHVIVPCSSCLLSCNNRHFWMFHSQAVYDINRLDSTGVNVLLRGNLPEIEESTDEDVLNISAEECIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6J4-1", "uniprot_id": "B0S6J4_DANRE", "id": "B0S6J4-1", "name": "", "aln": "MSTSN--FKNKCVTQINCIYCDSLLCTRGMKAVLLADTEIELFSTDIPPNRTVDFVASCYSTESCKCKLRDIACLKCGNVVGYHVVAPCKPCLLSCNNGHFWMFNSEAVSTINRLDATGQNLLLWGDLPELEDSDDESLESFSEEEYLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. **::**: : * :*..:*.:***********:*:*:******..:*** . ** * ****:*********:*****:.**..******* *****:*:** *****:** *.** *:*** *:. **. .:* ** :*", "identical_positions": 91, "similar_positions": 35, "identity": "61.07%" }, { "cls_id": "homologset.agr.HGNC:33595", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3Q0-1", "uniprot_id": "D4A3Q0_RAT", "id": "D4A3Q0-1", "name": "V-set and transmembrane domain-containing protein 2B", "aln": "MEQRNRLGALGYLLPLLLHSLLLFVADATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRLQDEGVYECRVSDYSDDDTQEHKAQALLRVLSRFTPPNMQAAEAVSHIQSSGPRRHGASSAVSSNNAGAALLTTSETSHDDKNPLPASPPSGSG--VPEAAAAAAASATHKATTMASAAAASSSASPPSGQAVLLRQRHGSGTGPGYSADPLLSLLLLALHKFLHPLLGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JME9-1", "uniprot_id": "VTM2B_MOUSE", "id": "Q9JME9-1", "name": "V-set and transmembrane domain-containing protein 2B", "aln": "MEQRNRLGALGYLLPLLLHSLLLFVADATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRLQDEGVYECRVSDYSDDDTQEHKAQALLRVLSRFAPPNMQAAEAVSHIQSSGPRRHGASSAVSSNNAGAAVRTTSETSHDDKNPPPGSPPAGSG--VPEAAAAAAS-ATHTATTTAAAAAASSSASPPSGQAVLLRQRHGSGTGPGYSADPLLSLLLLALHKFLHPLLGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NLU5-1", "uniprot_id": "VTM2B_HUMAN", "id": "A6NLU5-1", "name": "V-set and transmembrane domain-containing protein 2B", "aln": "MEQRNRLGALGYLPPLLLHALLLFVADAAFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRLQDEGVYECRVSDYSDDDTQEHKAQAMLRVLSRFAPPNMQAAEAVSHIQSSGPRRHGPASAANANNAGAASRTTSEPGRGDKSPPPGSPPAAIDPAVPEAAAASAA---HTPTTTVAAAAAASSASPPSGQAVLLRQRHGSGTGRSYTTDPLLSLLLLALHKFLRLLLGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************* *****:********:*******************************************************************************************************************:*******:**********************.:**..:****** ****..:.**.* *.***:. . *******:*: *..** .:****:********************** .*::***************: ****", "identical_positions": 246, "similar_positions": 29, "identity": "85.42%" }, { "cls_id": "homologset.agr.HGNC:33596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17533-1", "uniprot_id": "DFA29_MOUSE", "id": "P17533-1", "name": "Alpha-defensin 29", "aln": "MKTLVLLSALVLPCFQVQADPIQN-TDEETKTEEQPEEEDQAVSVSFGGTEGSALQDVAQRRFPWCRKCRVCQ-KCQVCQKCP-VCPTCPQCPKQPLCEERQNKTAITTQAPNTQHKGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3YX03-1", "uniprot_id": "D3YX03_MOUSE", "id": "D3YX03-1", "name": "", "aln": "MKTLVLLSALALLALQVQADPIQN-TDEETKTQEQPGEEDQAVSVSFGGTEGSALQDVAQRRFPWCRKCRVCQ-KCEVCQKCP-VCPTCPQCPKQPLCKERQNKTAITTQAPNTHHKGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17534-1", "uniprot_id": "DFAR2_MOUSE", "id": "P17534-1", "name": "Alpha-defensin-related sequence 2", "aln": "MKKLVLLFALVLLAFQVQADSIQN-TDEETKTEEQPGEKDQAVSVSFGDPQGSALQDAALG---WGRRCPQCP-RCPSCPSCP-RCPRCPRCK----CNPK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64263-1", "uniprot_id": "DAR10_MOUSE", "id": "Q64263-1", "name": "Alpha-defensin-related sequence 10", "aln": "MKKLVLLSAFVLLAFQVQADSIQN-TDEETKTEEQPGEENQAMSVSFGDPEGSALQDAAVG---MARPCPPCP-SCPSCPWCP-MCPRCPSCK----CNPK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4JEI5-1", "uniprot_id": "Q4JEI5_RAT", "id": "Q4JEI5-1", "name": "", "aln": "MKTLVLLSALVLLAFQIQADPIQE-AEEETKTEEQPADEDQDVSVSFEGPEPSALQNLEIR--WPWKRCHCRS-FCRPYENATSFCAQGLFKQHKFCCLETWPPRMK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1N8-1", "uniprot_id": "DFA22_MOUSE", "id": "Q8C1N8-1", "name": "Alpha-defensin 22", "aln": "MKKLVLLSALVLLAYQVQTDPIQN-TDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSR----DLICLCRKRRCNRGELFYGTCAGPFLRC----CRRRR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28311-1", "uniprot_id": "DEFA4_MOUSE", "id": "P28311-1", "name": "Defensin alpha 4", "aln": "MKTLVLLSALVLLAFQVQADPIQN-TDEETKTEEQPGEEDQAVSISFGGQEGSALHEKSLR----GLLCYCRKGHCKRGERVRGTCGIRFLYC----CPRR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4JEI9-1", "uniprot_id": "Q4JEI9_RAT", "id": "Q4JEI9-1", "name": "", "aln": "MKTLVLLSALVLLALQVQAEPTPK-TDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLR----DLKCFCRAKSCNWGEGIMGICNKRYGSL--ILCCR-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62715-1", "uniprot_id": "DEF2_RAT", "id": "Q62715-1", "name": "Neutrophil antibiotic peptide NP-2", "aln": "MRTLTLLTALLLLALHTQAKSPQG-TAEEAPDQEQLVMEDQDISISFGGDKGTALQDADVK---AGVTCYCRSTRCGFRERLSGACGYRGRIYR--LCCR-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LSU5-1", "uniprot_id": "F1LSU5_RAT", "id": "F1LSU5-1", "name": "", "aln": "MRTLTLLTALLLL-LHTQAESPQG-SPKEAPDQEQLDMEDQDISVFFGGDKGTALQDA------AGSTCSCRIGTCVSGEWLSWVCRINGRIYR--LCCR-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62714-1", "uniprot_id": "DEF4_RAT", "id": "Q62714-1", "name": "Defensin alpha 4", "aln": "MRTLTLLITLLLLALHTQAESPQE-RAKAAPDQD-MVMEDQDIFISFGGYKGTVLQDAVVK---AGQACYCRIGACVSGERLTGACGLNGRIYR--LCCR-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59665-1", "uniprot_id": "DEF1_HUMAN", "id": "P59665-1", "name": "Neutrophil defensin 1", "aln": "MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSR---KNMACYCRIPACIAGERRYGTCIYQGRLWA--FCC--------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*.:* :: * : *:.. : : : . : : : . :. * * * * ", "identical_positions": 9, "similar_positions": 20, "identity": "7.56%" }, { "cls_id": "homologset.agr.HGNC:336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29089-1", "uniprot_id": "AGTRB_RAT", "id": "P29089-1", "name": "Type-1 angiotensin II receptor B", "aln": "MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKN--TPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPS--DNMSSSAKKSASFFEVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29755-1", "uniprot_id": "AGTRB_MOUSE", "id": "P29755-1", "name": "Type-1 angiotensin II receptor B", "aln": "MILNSSIEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYQWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFVIILTSYTLIWKALKKAYKIQKN--TPRNDDIFRIIMAIVLFFFFSWVPHQIFSFLDVLIQLGVIHDCEIADVVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKARSHAGLSTKMSTLSYRPS--DNMSSSARKSAYCFEVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25095-1", "uniprot_id": "AGTRA_RAT", "id": "P25095-1", "name": "Type-1 angiotensin II receptor A", "aln": "MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKN--KPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPS--DNMSSSAKKPASCFEVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29754-1", "uniprot_id": "AGTRA_MOUSE", "id": "P29754-1", "name": "Type-1 angiotensin II receptor A", "aln": "MALNSSTEDGIKRIQDDCPRAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKN--KPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPS--DNMSSAAKKPASCSEVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30556-1", "uniprot_id": "AGTR1_HUMAN", "id": "P30556-1", "name": "Type-1 angiotensin II receptor", "aln": "MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKN--KPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPS--DNVSSSTKKPAPCFEVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5V1-1", "uniprot_id": "A0ACD6B5V1_DANRE", "id": "A0ACD6B5V1-1", "name": "Type-1 angiotensin II receptor", "aln": "MENQTSAMS--EDLHVNCSMSGRHGFIFTFIPVVYGCNFVIGIIGNSMVVAVIFRYMKLKTVANVFVLNLAISDLTFLITLPLWATFTATGYHWIFGAFLCKASAGMVIFNLYTSIFFLTALSIDRYLAIVHPVRSRRQRTLFYANLTCVLIWLFALLLSAPTALSRDVYDIG--NLTLCAVWHSSKQIHFLVTLSVLKSVLGFIVPFLIIITCYCLIGRALLGSRGLLRKSVRSREDETLRMIAATVLAFFVCWAPHQAFHFMELLATLGVVENCQTLDVIDTAMPFTICISYLNSCVNPILYGFVGHNFRKNLLRLLSCGSGEASNRFSINSKIDVNSHCNSGLLNQTSSKNDSASMVKAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* . : :: :*. :***.:**.:**.:*. **:**:***:** **: ********.**:****::** **:******.:** *:* ** .*** ::. * ****:*:*:**.************::** :**:: *::**::***:* * * *: : *:*: * *:*:**. :.*:: : : *.: *.:***:.**:**:*.* ** :** : : :: .*:*: :::* * ** **..* *** * *:::* **::.:*. *::*****:****:*:*.*:**::***:*::*:: :*:**. . * .: .:.:*:.. *: * * :*: ...* :..", "identical_positions": 161, "similar_positions": 125, "identity": "44.35%" }, { "cls_id": "homologset.agr.HGNC:3360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60841-1", "uniprot_id": "ENSA_RAT", "id": "P60841-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLP-SAGADKNLVTGDHIPTPQDLPQRKSS----------------LVT--SKLAGGQVE---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60840-1", "uniprot_id": "ENSA_MOUSE", "id": "P60840-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLP-SAGADKNLVTGDHIPTPQDLPQRKSS----------------LVT--SKLAGGQVE---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43768-1", "uniprot_id": "ENSA_HUMAN", "id": "O43768-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPERAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLP-SAGPDKNLVTGDHIPTPQDLPQRKSS----------------LVT--SKLAGGQVE---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BF67-1", "uniprot_id": "A2BF67_DANRE", "id": "A2BF67-1", "name": "Alpha-endosulfine", "aln": "MSSDNQ--DTETHPEQVDET------QESQDTN-SNPVRTEEAKLKAKYPNLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAGPDKNIVTGDHIPTPQDLPQRKSS----------------LVT--SKLAG-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8X2-1", "uniprot_id": "ENSA_DANRE", "id": "Q1L8X2-1", "name": "Alpha-endosulfine", "aln": "MSENPDDLELESEEKQCELKSGCVYLQDSPEKT-CNPILSEEAKLKAKYPSLGHKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKSKHVV-QSAAEKSLVTGDHIPTPQDLPQRKNT----------------ILT--SKLAG-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUB8-1", "uniprot_id": "Q9VUB8_DROME", "id": "Q9VUB8-1", "name": "", "aln": "MSSAEE--NSNSPATTPQDT------ETTEQANLTDLEKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAKQKGGGVKQV----FANKVTTGEAIPTPETVPARKTS----------------IIQPCNKFPATS-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9P305-1", "uniprot_id": "IGO2_YEAST", "id": "Q9P305-1", "name": "mRNA stability protein IGO2", "aln": "MS-EDLSPTSSRVDLSNPHG-------FTKEGVDLSKLSPQELKLYKMY---GKLPSK-KDLLRHKMQD-RQYFDSGDYALKKAGVIKSDDVIVNNSSNNLPVTNPSGLRESIIRRRMSSSSGGDS----------ISRQGSISSGPPP----------------------------RSPNK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53897-1", "uniprot_id": "IGO1_YEAST", "id": "P53897-1", "name": "mRNA stability protein IGO1", "aln": "MSNENLSPNSSNPDLTKLNN-------GESGTIDTSKFSPNEMKLYKMY---GKLPSK-KDIFKHTMQK-RKYFDSGDYALQKAGIQNND--PINYGKNNLPLTNPSKLREDIIKRRISTCPSTASTAGVVDNATLIQKEGSISSGPPSSNNGTIGGGSTSSTPVGNHSSSSSSLYTESPIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . :* ** * : *. . :: : :*. :::****** : * . :.: : : : *: : : ..:.. ", "identical_positions": 16, "similar_positions": 29, "identity": "8.79%" }, { "cls_id": "homologset.agr.HGNC:33600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9X5-1", "uniprot_id": "D4A9X5_RAT", "id": "D4A9X5-1", "name": "", "aln": "-----------MIQSESVNEDIPMWLWLASNKATRASRQRRSWQSAGAMAEPQEQLLQLQKDNRDGRLRKQELEELVRGLEAESESLTGRLDELRERERSLQRRRSQTSRAIRGEAREAARERAERARGLLEAAEQHRQDLEQHNRKLQEQWEELSSQLFYYGGEQLSQQRAEQQLGTQLVALQKHLELAEAKFSMQAEDLRQGTQRTEEAWASFQEQSGVLQELQGKVMEAAAALEATRSGSEPWNSQPRRVQDCSGSLMEEVARADCEKRLFGGAGAGSLRLWALSALQTLLLLPLGFLVLPLIYLVLARPDTIGPGLQSLGSDAVFRRLRYTLSPLLELRARGLLPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJB1-1", "uniprot_id": "T191_MOUSE", "id": "Q9JJB1-1", "name": "Transmembrane protein 191", "aln": "------------------------------------------------MTEPQEQLLQLQKDNRDGRLRKQELEELVRGLEAESESLTGRLEELRERERSLQRRRSQASRAIRGEACEAARERAERARGLLEAAEQHRQDLEQHNRKLQEQWEELSSQLFYYGGEQLSQQRAEQQLGNQLVALQKHLELAEAKFSMQAEDLRQGAQRTEEAWASFQEQSGVLQELQGKVMEAAAALEATRGGSEPWNSEPRPVQDCAGSLMEEVARADCEKRLFGGTGAGSLRLWALSALQTLLLLPLGFLVLPLIYVVLAKPDAVGPGLQSLGSDAVFRRLRYTLSPLLELRARGLLPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7N4-1", "uniprot_id": "T191B_HUMAN", "id": "P0C7N4-1", "name": "Transmembrane protein 191B", "aln": "MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLG-PRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEDLEQHSRQLQEQWEELSSQLFY-GGEPQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKVPPASPPPDLGR--CDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVLLTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .** ************ ******:*:**********. **::* ****** *****:::.::*** *********.* ** **:*::*****.*:************** *** **: :****. ***:**:.*****:* ::* *.*:*.: :* **** ****: *** . :...* .. * :.: * ** .: *****:**** *.*****. * ::* .*.***.** *** ** *.*:: ** *.::.. * ** *::.:***************.****:", "identical_positions": 181, "similar_positions": 68, "identity": "51.71%" }, { "cls_id": "homologset.agr.HGNC:33601", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9X5-1", "uniprot_id": "D4A9X5_RAT", "id": "D4A9X5-1", "name": "", "aln": "MIQSESVNEDIPMWLWLASNKATRASRQRRSWQSAGAMAEPQEQLLQLQKDNRDGRLRKQELEELVRGLEAESESLTGRLDELRERERSLQRRRSQTSRAIRGEAREAARERAERARGLLEAAEQHRQDLEQHNRKLQEQWEELSSQLFYYGGEQLSQQRAEQQLGTQLVALQKHLELAEAKFSMQAEDLRQGTQRTEEAWASFQEQSGVLQELQGKVMEAAAALEATRSGSEPWNSQPRRVQDCSGSLMEEVARADCEKRLFGGAGAGSLRLWALSALQTLLLLPLGFLVLPLIYLVLARPDTIGPGLQSLGSDAVFRRLRYTLSPLLELRARGLLPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJB1-1", "uniprot_id": "T191_MOUSE", "id": "Q9JJB1-1", "name": "Transmembrane protein 191", "aln": "-------------------------------------MTEPQEQLLQLQKDNRDGRLRKQELEELVRGLEAESESLTGRLEELRERERSLQRRRSQASRAIRGEACEAARERAERARGLLEAAEQHRQDLEQHNRKLQEQWEELSSQLFYYGGEQLSQQRAEQQLGNQLVALQKHLELAEAKFSMQAEDLRQGAQRTEEAWASFQEQSGVLQELQGKVMEAAAALEATRGGSEPWNSEPRPVQDCAGSLMEEVARADCEKRLFGGTGAGSLRLWALSALQTLLLLPLGFLVLPLIYVVLAKPDAVGPGLQSLGSDAVFRRLRYTLSPLLELRARGLLPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGB0-2", "uniprot_id": "T191C_HUMAN", "id": "A6NGB0-2", "name": "Transmembrane protein 191C", "aln": "-------------------------------------MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVLLTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .** ************ ******:*:**********. **::* ****** *****:::.::*** *********.* ** **:*:: ****.*:****************** **: :****. ***:**:.*****:* ::* *.*:*.: :* **** ****: ****:* ****** *:* :.* * :.: * ** .: *****:**** *.*****. * ::* .*.***.** *** ** *.*:: ** *.::.. * ** *::.:***************.****:", "identical_positions": 191, "similar_positions": 65, "identity": "56.34%" }, { "cls_id": "homologset.agr.HGNC:33605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z830-1", "uniprot_id": "D3Z830_RAT", "id": "D3Z830-1", "name": "", "aln": "--MGYFLFFRLFLLWVLAAFSQGKRLSPTSPLRYSRFLDPSHAVFLRWDFDYETEIITFELQVQTTGWVGLGITDRYTFVGSDLVVGGVLPNGNVYFSDQHLLDEDTLEQDGSQDAELLKLTEDSVSTTMRFSRPFRSCDPHDHDITSDTMRVLAAYGLDDIPKMNRERTFVKSIFLLQILQYDDEDAPEDTVIYDLKISNFLIPEEDTTYACTFLPLPIVSKKHHIYKFEPILVERNETMVHHVLVYACGNSSVLPTGIGECYGADPAFSLCSHVIAGWAVGGLSYQFPDDVGISIGTPFDPQWIRLEIHYSNFQNLPGIRDTSGMRLYYTSHLRKYDMGVLQLGISVFPIHFIPPGAEAFLSYGLCKTDKFEEMNGAPVADIYVSACLLHTHLAGRSLQALQYRNGTQLQIVCKDFSYDFNLQESRDLPHPVVIKPGDELLIECHYQTLDRDFMTFGGASTINEMCLIFFFYYPRINISSCMGYPDIIYVTNELGEEASENPMENLMVLNNVEWTPENIKTAEKACKESQQTVLIKTIDEEVENTTGWIPDIIPTPRGACLESSGGKVEPQDKTPAGFRAVPMALSGSNTATLRHLPMITVLFLQGCLSWLLAMLQTGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT41-1", "uniprot_id": "MOXD2_MOUSE", "id": "Q7TT41-1", "name": "DBH-like monooxygenase protein 2", "aln": "--MACVLLFRLFLLLVLAAFSQGKRLGPTSPLRYSRFLDPSRAVFLRWDFDYEAEIITFELQVQTTGWVGLGITDRYTFVGSDLVVGGVLPNGNVYFSDQHLLDEDTLEQDGSQDAELLRLTEDAVSTTMRFSRPFRTCDPHDRDITSDTMRVLAAYGPDDIPKMSREHTFVKSIFLLQMLQYDDQDAPEDTIIHDLKISNFIIPEDDTTYACTFLPLPIVSKKHHIYKFEPILVERNETMVHHVLVYACGNSSVLPTGIGECYGSDPAFSLCSHVIAGWAVGGLSYQFPDDVGISIGTPFDPQWIRLEIHYSNFQNLPGIRDTSGMRLFYTSHLRKYDMGVLQLGISVFPIHFIPPGAEAFLSYGLCKTDKFEELNGAPVSDIYISACLLHTHLAGRSLQALQYRNGTQLQVVCKDFSYDFNLQESRDLPHPVVIKPGDELLIECHYQTLDRDFMTFGGASTINEMCLIFFFYYPRINISSCMGYPDIIYVTNELGEEASENPMENLMVLDNVEWTPENIKKAEKACKESQQTVLIKTIDEEVENTTGWIPDIIPTPRGPCLESTGGKVEPQDNTPAGFRAVPLALSGSNTATLRPLPMIAVLFLQGSLSCLLAMLQTGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHM9-1", "uniprot_id": "MOXD2_HUMAN", "id": "A6NHM9-1", "name": "Putative DBH-like monooxygenase protein 2", "aln": "--MAHDLLFRLFPLLALGVPLQSNRLGPTSRLRYSRFLDPSNVIFLRWDFDLEAEIISFELQVRTAGWVGFGVTNRYTNVGSDLVVGGVLPNGNVYFSDQHLVEEDTLKEDGSQDAELLGLTEDAVYTTMHFSRPFRSCDPHDLDITSNTVRVLAAYGLDDTLKLYRERTFVKSIFLLQVVHPDDLDVPEDTIIHDLEITNFLIPEDDTTYACTFLPLPIVSEKHHIYKFEPKLVYHNETTVHHILVYACGNASVLPTGISDCYGADPAFSLCSQVIVGSAVGGTSYQFPDDVGVSIGTPLDPQWI-LEIHYSNFNNLPGVYDSSGIRVYYTSQLCKYDTDVLQLGFFTFPIHFIPPGAESFMSYGLCRTEKFEEMNGAPMPDIQVYGYLLHTHLAGRALQAVQYRNGTQLRKICKDDSYDFNLQETRDLPSRVEIKPGDELLVECHYQTLDRDSMTFGGPSTINEMCLIFLFYYPQNNISSCMGYPDIIYVAHELGEEASE-----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CS6-1", "uniprot_id": "MOXD2_DANRE", "id": "Q08CS6-1", "name": "DBH-like monooxygenase protein 2 homolog", "aln": "MGTCLKGNMSVLSLVLFLLSVQQFWAQEDPLLPFSEHLDLEHNVQLKWGFDKIQGTILFQLSVNTSGWISFGLSPNGGMTGADIVIGGVDNKG-TYFTDRHALGNSMPVVDQKQNYKLLSLSESDGKTVMKFQRSIESCDENDLPVTILPMKLIYAYGETDDISYHKAQRGTKEVNLLKYMPR---ASLSNATYFDITMENFMLPANQTYYHCKTARAPTFDSKQHIYRIEPVIT--NYDLVHHLLLYRCPPTVTEPLEL-ECYTKT---ERCMETIAVWGVGGGDFEFPEVAGLPIGGNVGDFFYRLEVHYNNVNKTAGRVDSSGLRFYYTSKLRQHDAGILMTGLAVIPSYAIPPKAKSFLTYGMCDTTYIPKVLET-ANDLQVFSVMMHTHLAGRKVRVGHFREGKQIDLLAVDENYNFEFQQVTNLGKTKTVKLGDKLLVECTYNTENRNTLTQGGLSTSDEMCLAFLFYYPAMNLSGCESLPHFSSLVSEMGAGDTG---TWLYMMNTMAWNDSSINEYQQTLKKINQTVIVVNSFNKASITNGTIPDLKVSPPEPCVRACATKN-------LAFMSLFLCLAGMWAS----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * : * . * :*..** .. : *:*.** * *:*.*.*:**:.:*:: . .*:*:*:*** :* .**:*:* : :. * .*: :** *:*. *.*:*.*.:.:** :* :* .:::: *** * . : : .*.: **: : .:: .*: : **::* ::* * *. * ...*:***::** :. * ***:*:* * : . * : :** . * ..*. .*** .::**: .*:.** .. : **:**.*.:: .* *:**:*.:***:* ::* .:* *: .:* : *** *::*::**:* * : :: : *: : . ::******* ::. ::*:*.*: :. * .*:*::*: :* :* **:**:** *:* :*: :* ** ** :**** *:**** *:*.* . *.: :. *:* : ", "identical_positions": 157, "similar_positions": 168, "identity": "25.28%" }, { "cls_id": "homologset.agr.HGNC:33609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6P320-1", "uniprot_id": "MARHB_RAT", "id": "A6P320-1", "name": "E3 ubiquitin-protein ligase MARCHF11", "aln": "MSDEGSKRGSR---ADSLEAEPPLPPPPPPP---PPGESSLVPTSPRYRPPLPAP---LERIVGSGEPPVELAPRRK--GEPLPPLPPSRLPGDQEVSAAGDSCEGPRRLPEVKLPEAAAGKGSPAEPEAGACREGERRGTGDQPETRSVYSSRSSSSGGSGDQRSGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVTAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLSALRNRNLVHPTQLTSPRFQCG-YVLLHLFNR-MRAHEDVS-EDNGSGEVVMRVTSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBH7-1", "uniprot_id": "MARHB_MOUSE", "id": "Q8CBH7-1", "name": "E3 ubiquitin-protein ligase MARCHF11", "aln": "MSDEGKKRSSR---ADSLEAEPPLPPPPPPP---PPGESVLVPTSPRYRPPLPAP---LERIVGSGEPPVELAPRRKGAGEPLPPLPPSLLPGDQEVTAAGDSCEGPRRLPEVKLPEAATGKGSPGEPEAGACREGERRGTGDQPETRSVCSSRSSSSGGGSDQRSGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVTAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLSALRNRNLVHPTQLTSPRFQCG-YVLLHLFNR-MRAHEDVS-EDNGSGEVVMRVTSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNE9-1", "uniprot_id": "MARHB_HUMAN", "id": "A6NNE9-1", "name": "E3 ubiquitin-protein ligase MARCHF11", "aln": "MSFEGGHGGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRG-ADELPPPPLPLQPAGQEVAAAGDSGEGPR-----RLPEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGG-GDQRAGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLTALRNRNLVHPTQLTSPRFQCG-YVLLHLFNR-MRPHEDLS-EDNSSGEVVMRVTSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q1P8-1", "uniprot_id": "A0A8M1Q1P8_DANRE", "id": "A0A8M1Q1P8-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--------------MDVHAEAGPLHVQAVDE---PPGGATVTVTAAQFQP---------QTVPGSD-------------GEDVLQEPGAGVQTPSPAAAEADP-----------ITEIESEDG----ACAGTDTLLEDSGGQSAVKTETVGSSCS------------NESCIPTPGCRICFQGAEQGELLSPCRCAGSVRHAHQQCLLKWISEKGSWSCELCNYRFNILPIHIKSPQQWQRVTMTLVEKVQVIAVFLGGLFLLASVSWLLWSALSPEALWQRSDILFQICYGMYAVMDLVCIGLIVHEGGAVYNVLLRWRAVNLLWDVQNYDKSRDLENT----HSPHRNLWLPLTHTHR---VSNTHTQTTRLESSPRCPLHLFSMCLNGTTNLSPQEQGSGELVVRVTSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . *** . . ::.:: * : *.. .: : * . . .:* .*. :.* : .* . **: * * . :*.:* ** * :: * *:************.**** ****::** ********:***:**** **::: .*::*.* *** :::*******:***:**.***:***:******:** *:***.***********..*************.***.*: ******* *** ****: *:*:: *. *.*****: :. * *: :.*::.. ****. :. ::* :::.***:*:*****", "identical_positions": 165, "similar_positions": 89, "identity": "40.05%" }, { "cls_id": "homologset.agr.HGNC:33624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1Q8-1", "uniprot_id": "D4A1Q8_RAT", "id": "D4A1Q8-1", "name": "Bcl-2-like protein 15", "aln": "MSKMKNPRTFEEQTECIMNTLLTDFLTPTFQAANRNLPDADEPCSGEDYSFDVAIVAGRLRMLGDKFNGELEASVNNIIAETIRGQAG-TVLKDTVQSLSKTWCTQNPTLAFETAFLAVSVKLLEYVARKAPEMASQVAACMTGMINGDTTIRQFIQDLGGWGNLEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08ED0-1", "uniprot_id": "B2L15_MOUSE", "id": "Q08ED0-1", "name": "Bcl-2-like protein 15", "aln": "MSKMKNPRTFEEQTECIVNSLLKDFRTPLSHAANRNLSGADEPCSGEDYSFDVAIIVGRLRILGDQFNGELEASANNIIAVTIGGQAGSTVLNDTVQSLSRTWCTQDPTLVFERAFLAVSVKLLEYVVRKAPNVARQVANYVTGMINGNTAIREFIQGQGGWENLES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TBC7-1", "uniprot_id": "B2L15_HUMAN", "id": "Q5TBC7-1", "name": "Bcl-2-like protein 15", "aln": "---MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRMLGDQFNGELEASAKNVIAETIKGQTG-AILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLLEYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..:*********:*:** ** :* :.*.*** .** *** ******:.****:***:********.:*:** ** **:* ::*:***:***:***:*:.:*.:* ************:.: **::. *** :******: :**:***. *** ***.", "identical_positions": 102, "similar_positions": 41, "identity": "61.08%" }, { "cls_id": "homologset.agr.HGNC:33627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LTT8-1", "uniprot_id": "F1LTT8_RAT", "id": "F1LTT8-1", "name": "", "aln": "MWCLERL-----------------LRDRDGFLPGRARRSKARSSAACANVLTPDRIPEFCIPPRLEP----------------------------------STASAALRDAWAADVESDDGAG---LTDWDPRSQAALSLPHLPRARTVYGFCALLESPHTRRKESLFLGHL---GAPVRRP---GLRHRTHTYASPHRVSDAPRPA----------------------------PGDPDAARVPTPTPAPSRR--RLLHSP--GRLLSRALR---APR--GPARARPGSRGDE------------------HERAASCAPPAPTRPDPQRLQAEANVALGRGGCTLRLAAEYCPRSACLRLRLLRAEGPAA-VLEPRALGCRLSLVLRPSG---QQRASVVRRSRKAALDQDCCFDGLPEEQLRRLAVRIKAESKGRGLERRRPLGQGELLLGSLLLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q861-1", "uniprot_id": "E9Q861_MOUSE", "id": "E9Q861-1", "name": "", "aln": "MWCLERL-----------------LRDRDGFLPGRVHRSKARSSAACANVLTPDRIPEFFIPPRLEP----------------------------------STAWAALREAWAADTEADDGAG---RTDWDPRSQAALSLPHLPRARTAYGFCALLESPHTRRKESLFLGHP---GVPVRRP---GLRHRTHTYASPRRVPDAPRPA----------------------------PGDPDAARVPTPTPAPSRR--RLLRSP--GKLLSRALR---APR--RLASARPPCRGDE------------------HERAASCAPPVPSSPDPERLQAEASVALGRGGCTLRLAAEYCPRSACLRLRLLRAEGPAA-ALEPRALGCRLSLVLRPSG---QQRASVVRRSRKAALDQDCCFDRLPEEQLRRLAVRIKAESKGR------RLGQGELLLGSLLLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCU7-1", "uniprot_id": "C2C4A_HUMAN", "id": "Q8NCU7-1", "name": "C2 calcium-dependent domain-containing protein 4A", "aln": "MWCLERLRLGPECL----------RRSGDWLLPGRARGAKSRTTAACANVLTPDRIPEFCIPPRLMP----------------------------------RLALAALRNSWVEEAGMDEGAG---RTDWDPRSQAALSLPHLPRVRTAYGFCALLESPHTRRKESLLLGGP---PAPRPRAHTYGGGGGPDALLGTLRVPRAPGPAT---------------------------PAAPGCPRPPQDALARRPRGCRLLRVP--DGLLSRALR---AGRSRRLTRVRSVSSGNEDKERRAGSQ--------SPARAPSTSPPSSRVPFPERLEAEGTVALGRAGDALRLAAEYCPGTGRLRLRLLRAESPAGGAPGPRAVSCRLSLVLRPPGTALRQCSTVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRERGRLLGQGELSLGALLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TFI7-1", "uniprot_id": "A0AB32TFI7_DANRE", "id": "A0AB32TFI7-1", "name": "", "aln": "MWVVEKIRVSVERTNLPLPITEYSFKLGDIMFGDKSSIDKAKKVLLCPNIITPDTIPEFCIPPKISSPMEGKNIELGRQTPCIRVSPCEKGSPKREIVSREMTNNHIIQVESVDDGPYDNGCSDEETTNADPQSQAALSLPHLAKAQTCYGFCTLLESPHTRRKESLFHNDPNSSGIPLVLPRSRSSTCSKSSLSASPLLPSSYSPSSFSLNSLTSRLSPKGFTLHRQGTLDSDTTSSAESSPFSSPLLNRCPQKSSLLKALNHENLLYRNLRKAAMSRNNSLSTDEGSSTDNSPNVMRRASEGLVEPLPCGFGLAPPAIFPMDLVLHRERVMKENLVPVGREG-TLRLSAEYCPENQRLRVRLISAEGLYALSVDPKSINCSVSLSLMPGKIQ-KQRSTVIRKSRNPIFNEDFFFDGITEDDLCQRSLRFKVVNKMSTMKRDYILGSYDLPLTSIVTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*:: : * :: .: *::. *.*::*** **** ***:: . :: . : *:*.. *: **:**********.:.:* ****:*************: . * . . : .. :. : *: .. . .. . : **: ** * ** * : . . .:. *.. * :*: * *.:** * :***:***** . **:**: **. . *:::.* :** * * :* ::*: :**:. :::* ** :.*::: : ::*.*. .: **. :* * ::: *", "identical_positions": 103, "similar_positions": 101, "identity": "22.44%" }, { "cls_id": "homologset.agr.HGNC:33628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9N9-1", "uniprot_id": "A0A8I6A9N9_RAT", "id": "A0A8I6A9N9-1", "name": "", "aln": "MRLLGRLR-----SSTPEPAFSN--------------------------VLTPGRIPEFCIPPRLP-------------------VPDAPESPLPAASLPWRCAAEPDLWPRTHDGRENGDEDGAGLTDWDPRSQAALSLPHLPRARTVYGFCALLESPHTRRKESLFLGHP---GTPRLGFRHRAHTCAWQRR--ASDSE-----------------------LAAPRDLDTAPSVAP------------VPHVRRLLRAP--DGLLSRALR---VPRGR--ATARPGSRGDERE------------------RAASCAPPAPTGPDPERLQAEANVALGRGGCTLRLAAEYCPRSACLRLRLLRAEGP-AAELEPRALGCRLSLVLRPSGQQR---ASVVRRSRKAALDQDCCFDGLPEEQLRRLAVRIKAESKGRGLERRRPLGQGELLLGSLLLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NLJ0-1", "uniprot_id": "C2C4B_HUMAN", "id": "A6NLJ0-1", "name": "C2 calcium-dependent domain-containing protein 4B", "aln": "MRLLEKLCSSAAGSSAPKPAFAK--------------------------VLTPNRIPEFCIPPRLP-------------------APCTLESPIRAAAVPRRCAAESDLWPRAAD-------EDAGRTDWDPRSQAALSLPHLPRVRTTYGFCALLESPHTRRKESLLLGGP---PAPRP----RAHSCGGGGGPDAPLGT-----------------------LCGPRGPGPATPAAPGGPRLPQDALAAGPRRCRLLRVP--DGLLSRALR---AGRSRRLARVRSVSSGNEDEERRAGSE--------SPARAPSSSPLSSRAPLPERLEAKGTVALGRAGDALRLAAEYCPGTRRLRLRLLRAESLFGGAPGPRAVRCRLSLVLRPPGTARWQCSAVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRDRGRLLGQGELSLGALLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TFI7-1", "uniprot_id": "A0AB32TFI7_DANRE", "id": "A0AB32TFI7-1", "name": "", "aln": "MWVVEKIRVSVERTNLPLPITEYSFKLGDIMFGDKSSIDKAKKVLLCPNIITPDTIPEFCIPPKISSPMEGKNIELGRQTPCIRVSPCEKGSPKREIVSREMTNNHIIQVESVDDGPYDNGCSDEETTNADPQSQAALSLPHLAKAQTCYGFCTLLESPHTRRKESLFHNDPNSSGIPLVLPRSRSSTCSKSSLSASPLLPSSYSPSSFSLNSLTSRLSPKGFTLHRQGTLDSDTTSSAESSPFSSPLLNRCPQKSSLLKALNHENLLYRNLRKAAMSRNNSLSTDEGSSTDNSPNVMRRASEGLVEPLPCGFGLAPPAIFPMDLVLHRERVMKENLVPVGREG-TLRLSAEYCPENQRLRVRLISAEGLYALSVDPKSINCSVSLSLMP-GKIQKQRSTVIRKSRNPIFNEDFFFDGITEDDLCQRSLRFKVVNKMSTMKRDYILGSYDLPLTSIVTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: :: :. * * ::**. ********::. * ** . . * .. *: **:**********.:.:* ****:*************: . * * *: :*. :. * .. .. :. *: **:. :.** * ** *.. : . * .:. : *... **: : *.:** * :***:***** . **:**: **. . *::: * :** * * * : ::*: :**:. :::* ***:.*::: : ::*.*. .: .* **. :* * ::: *", "identical_positions": 107, "similar_positions": 95, "identity": "23.31%" }, { "cls_id": "homologset.agr.HGNC:33629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPP8-1", "uniprot_id": "CCD61_RAT", "id": "A0JPP8-1", "name": "Centrosomal protein CCDC61", "aln": "MEQPAGLQVDYMFRGVEHAVRVVVSGQVLELEVEDRMTADQWRGEFDANFIEDLTHKTGNFKQFSIFCNMLESALTQSSESVTLDLLTYTDLESLRSRKLG--GRPGP-CPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGHLRGMNGG--QDARETEIWHLREQVTRLASEKRELEAQLGRSREEALAGRAARQEAESLRGLVRGLELELRQERGLGGRAAGRRSQDCRRLAKELEEVKASERNLRARLKTLNCELAMYRRGRRTLP----AGARED---RALSSRERSTSRGRTATRSSSRE--SNRGARSHGRP------------AHPSPSPTGSRVPRFDPTAFVKAKEKKQREIRMKRQQQQQQQRNRMGSGGSGDGPSVSWSHQTRPPAAVTGRGDAANRSRNRSSSVDSFRSRCSSVSSCSELEDFSQSVSKSRRCRGRGKPPSPIPWSGSKTKSTTRERNNHQRHLASSGAWVPIKEYSSDYQGADMAEIDARLKALQEYMNRLDTRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UJV1-1", "uniprot_id": "CCD61_MOUSE", "id": "Q3UJV1-1", "name": "Centrosomal protein CCDC61", "aln": "MDQPAGLQVDYIFRGVEHAVRVVVSGQVLELEVEDRMTADQWRGEFDANFIEDLTHKTGNFKQFSIFCNMLESALTQSSESVTLDLLTYTDLESLRSRKLG--GRPGALAPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGHLRGLNGG--QDARETEIWHLREQVTRLTSEKRELEAQLGRSREEALAGRAARQEAESLRGLVRGLELELRQERGLGGRAAGRRSQDSRRLAKELEEVKASERNLRARLKTLNSELAMYRRGRRTLPP---VAVREG---RASSSRERSTSRGRAVTRSSSRE--SSRGARGRGRP------------AHPSPSPTGSRAPRFDPTAFVKAKEKKQREIRMK---QQQQQRNRMGSGGSGDGPSVSWSQQTRPAAAVTGRGDAVNRSRNRSSSVDSFRSRCSSVSSCSELEDFSHSVSRSRRCRGRGKPPSPTPWSRSKTKSTTQERSDHQRHLASSGGWVPIKEYSSDFQGADMAEIDARLKALQEYMNRLDTRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6R9-1", "uniprot_id": "CCD61_HUMAN", "id": "Q9Y6R9-1", "name": "Centrosomal protein CCDC61", "aln": "MDQPAGLQVDYVFRGVEHAVRVMVSGQVLELEVEDRMTADQWRGEFDAGFIEDLTHKTGNFKQFNIFCHMLESALTQSSESVTLDLLTYTDLESLRNRKMG--GRPGSLAPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGRRTPPVQP-PPTRED---RASSSRERSASRGRGAARSSSRE--SGRGSRGRGRP------------ARPSPSPTGGRALRFDPTAFVKAKERKQREIQMK-----QQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRR-RGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAADMAEIDARLKALQEYMNRLDMRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CF3-1", "uniprot_id": "CCD61_DANRE", "id": "Q08CF3-1", "name": "Centrosomal protein CCDC61", "aln": "MEVGTVVQEEMKFRGSEFAVKVEMAERLLIVEISDVVTADQWRGEFGPAYIEDLTRKTGNFKQFPVFCSMLESAVHKSSDSVTLDLLTYSDLELLRNRKAGVVGRPRA-QPQSPALSAKRYLILIYTVEFDRIHYPLPLPYLGKPDPAELQKEIRALRSELKTLG-LRGD--HKVSDQETRKLRTELALVRDEKEALAKALDR---LQMVGSGSAPGARGLREAVHSLEEQLLKERAKSQRSAIKKSQEQRLLVEQLEELRASERALRIRVKSLTTELALLRRGRATPVLSDRGGLRGDGVVHRSLSRERSLTRVGIRARSGSRERIEDRGRRSEERVRRADSSGSRNCITRPSPSPTGSRVPRFDPTAYIQDRQRRQKEAELK-----SQRKIRRDMLAS---PSLMERGRSRSREPVPQLMRAGSAGRGRSVSVESRRSRCSSEGSVAEFEELAKPLNS------RGRK------LMSNGPAVSRGRHINKKPMCSTPAQRMRAGDTSMDTGADLSEIDARLQALQDYMRDLDTGH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : :* : *** *.**:* :: ::* :*:.* :*********.. :*****:******** :** *****: :**:*********:*** **.** * *** . *:*. *.:********:************** *****. ** **:*:.** * : * :.. : * :** ::: : .**. * *.* :.* .: *..** *:.** :* :**. . * * ::.*: * *.::*** :**** ** *:*:*. ***: :*** * * . : ***** :* :**.*** ..** *.. * ::*******.*. ******::: ::::*:* .:* .*:: * . .* **: :::. .:. * . .*.** **:* ****** .* :::*:::..:. **: *: : . * ::: :..: . :* .**::******:***:**. ** ", "identical_positions": 217, "similar_positions": 142, "identity": "40.33%" }, { "cls_id": "homologset.agr.HGNC:3363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97687-1", "uniprot_id": "ENTP1_RAT", "id": "P97687-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 1", "aln": "MEDIKDSKVKRFCSKNILIILGFSSVLAVIALIAVGLTHNKPLPENVKYGIVLDAGSSHTNLYIYKWPAEKENDTGVVQLLEECQVKGPGISKYAQKTDEIAAYLAECMKMSTERIPASKQHQTPVYLGATAGMRLLRMESKQSADEVLAAVSRSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRFTQEQSWLNFIS-DSQKQATFGALDLGGSSTQVTFVPLNQTLEAPETSLQFRLYGTDYTVYTHSFLCYGKDQALWQKLAQDIQVSSGG----ILKDPCFYPGYKKVVNVSELYGTPCTKRFEKKLPFNQFQVQGTGDYEQCHQSILKFFNNSHCPYSQCAFNGVFLPPLQGSFGAFSAFYFVMDFFKKMANDSVSSQEKMTEITKNFCSKPWEEVKASYPTVKEKYLSEYCFSGTYILSLLLQGYNFTGTSWDQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYISLMVLFSLVLVAMVITGLFIFSKPSYFWKEAV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55772-1", "uniprot_id": "ENTP1_MOUSE", "id": "P55772-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 1", "aln": "MEDIKDSKVKRFCSKNILIILGFTSILAVIALIAVGLTQNKPLPENVKYGIVLDAGSSHTNLYIYKWPAEKENDTGVVQQLEECQVKGPGISKYAQKTDEIGAYLAECMELSTELIPTSKHHQTPVYLGATAGMRLLRMESEQSADEVLAAVSTSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRFTQEQSWLSLIS-DSQKQETFGALDLGGASTQITFVPQNSTIESPENSLQFRLYGEDYTVYTHSFLCYGKDQALWQKLAKDIQVSSGG----VLKDPCFNPGYEKVVNVSELYGTPCTKRFEKKLPFDQFRIQGTGDYEQCHQSILELFNNSHCPYSQCAFNGVFLPPLHGSFGAFSAFYFVMDFFKKVAKNSVISQEKMTEITKNFCSKSWEETKTSYPSVKEKYLSEYCFSGAYILS-LLQGYNFTDSSWEQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYIGLMVLFSLLLVAVAITGLFIYSKPSYFWKEAV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49961-1", "uniprot_id": "ENTP1_HUMAN", "id": "P49961-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 1", "aln": "MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNE----ILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFLNLTSEK--VSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDMV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5W7-1", "uniprot_id": "A0ACD6B5W7_DANRE", "id": "A0ACD6B5W7-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 1", "aln": "MDEQGEVKVKNPWHRPVVIFLMAVVAVGIVIMVSISVVQHKPLPQKYKYGIVLDAGSSHTSVFIYKWPAEKENNTGMVQQHHTCNVKGKGISSYFDKPHGAGASLEECMKEAKEKIPAHRHSETPVYLGATAGMRLLKMEDEMASEKVLTSVAHSLKTYPFSYQGARILSGQEEGAFGWITVNYLSENLRKP-------------AGTLGALDLGGASTQITFVP-QQIIESSDNSIDFRLYGNDYHLYTHSFLCYGKDQALKLAMAEKLRSTPDKTDAILLRDPCFHPGYNTTKTLESVN-TPCMK--PLKMPKEQFSHVGLGNWSQCQESIRKVFNTSHCPYSGCSFNGVFQPTVEGKFGAFSAFFFVMDFLNLKNDS----LDKTKQRLAMYCSTPWQKIVQDHPKVKEKYLSEYCFSATYILTLLEHGYNFTSDNWNDIKFIKKIGDSDAGWTLGYMLNLTNMIPAEDPDKPLMPHGGYVTFMILFSLLILVLIIMAYIYFRRFTKTAQKDII", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : :** : :: :* :.:: ::::.:.::*.**:: *************.::**********:**:*: . *.*** ***.: :* . . * :**: : * ** :: :**************:**.: ::.** * **..***.:***:*::******:****:*** .: : *:*******:***:**** :. :*:.:.:::***** ** :************** :*:.:: :.. :*:**** ***:.. .:..: *** * .:* :** * *::.**::** :.**.*:**** *:***:* *.:.*.*******:***.*:: .. :* .: :*: .*:: .:. ************.:***: * :**:** .*:.*:*: ** .*:******************:* .. :.*. *: :*:****::..: * . : : : : :. : ", "identical_positions": 228, "similar_positions": 162, "identity": "44.1%" }, { "cls_id": "homologset.agr.HGNC:33630", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z954-1", "uniprot_id": "D3Z954_RAT", "id": "D3Z954-1", "name": "", "aln": "-----------MKCLEGLHLQHRPSKFSVPLAP----------EEGLECAFQLEEEE--------KENEEKF--------------------VCSDWAPEGK------------------------------------------------------------------------------------EEGND----------------------------LWDPAIVSAIQNTQV-----------PQQRGLHSSPTVRASGALGMSPASLHFLCQS-------------VFPRTS---SPAHHFG---------------------------------------PQQP------------------------------------------------------SPDPFLFCSPLTPWPPKLRLPSHLTQLHP----------------QHQKILQQQQ---QQWSQTARRVPGQKPRSRE-------------------SDAYANLMTRKEKDWVIRVQMVQLQSENPRLDDYYYQKYYQKLEKRQ-------------------------------------ADQELLGQRNRAQSLKLVTPYIQKSE---------VYESVVRIEGSLGQVAVSTCFS-PRRAIDAVSHG--------------------------TQEQDTGAASSQRLRVLSQIEKMFLQLLKIEEGQN---DGLPQHYHLREQ--SNQVEKLFQALKTQEQNNLEEAA--------------------------------DNLLQVLSVRKGKIFVARLLPFLLQDQAVSLLLY---ITYHLPLLIQRDMADQSLQMLFKPLRKYIRHLTFPQLLHALQG--------LMLLSPDSSERPVSVVLQNQFGISLLYALLSHGEQLVS-LDSSLQ-SSSDCVAWTDLVILVAWEIAQLPAASLAEPLAFPRNLLPLFYHHMDQQLVQQLEARMELAYIY-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ARM1-1", "uniprot_id": "PATL2_MOUSE", "id": "A2ARM1-1", "name": "Protein PAT1 homolog 2", "aln": "-----------MKCLEGLHLQQRPSKFSVSLAP----------EEGLVCAFQLEEE---------KENEDEC--------------------VCSDQAPEVK------------------------------------------------------------------------------------EEGCG----------------------------LGDPAIVSAFQNTQV-----------PQQRGLHSSHRVKVSGALGMSSASLHFMWQS-------------VFPRAS---SPAHHFG---------------------------------------PQQP------------------------------------------------------SPDPFLFYSPLTPWPPKLSLPSHLTQLHP----------------QHQQILQQQQRWRRRRSPTARSVPAQKPWSREP----------------AASDAYANLMTRKEKDWVIRVQMVQLQSENPRLDDYYYQKYYQKLEKRQ-------------------------------------ADKELLGQKTRAESLKLVTPYIQKPE---------VYESVVRIEGSLGQVAVSTCFS-PRRAIDAVSHG--------------------------TQEQDTGAASSQRLRVLSQIEKMFLQLLKIEEGQN---DGLPQLYHTREQ--SSQVEKLFQALKTQEQNNLEEAA--------------------------------DNLLQVLSVRKGKVLVARLLPFLPPDQAVSLLLY---ITYHLPLLIQRDMADQGLHMLFKPLGKYISHLTFHQLLHAMQG--------LMLLSPGSSERPVSVVLQNQFGISLLYALLSHGEQLVS-LDPSLR-SSSDCATWTDLVILIAWEIAQLPAASLAEPLAFPRNLLPCSAITWTSN----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C9JE40-1", "uniprot_id": "PATL2_HUMAN", "id": "C9JE40-1", "name": "Protein PAT1 homolog 2", "aln": "-----------MNCLEG------PGKTCGPLAS----------EEELVSACQLEKEEENEGEEEEEEEDEED--------------------LDPDLDPDLE------------------------------------------------------------------------------------EEEND----------------------------LGDPAVLGAVHNT---------------QRALLSSPGVKAPGMLGMSLASLHFLWQTLDYLSPIPFWP--TFPSTS---SPAQHFG---------------------------------------PRLP------------------------------------------------------SPDPTLFCSLLTSWPPRF---SHLTQLHP----------------RHQRILQQQQ-----HSQTP-SPPAKKPWSQQ-------------------PDPYANLMTRKEKDWVIKVQMVQLQSAKPRLDDYYYQEYYQKLEKKQ-------------------------------------ADEELLGRRNRVESLKLVTPYIPKAE---------AYESVVRIEGSLGQVAVSTCFS-PRRAIDAVPHG--------------------------TQEQDIEAASSQRLRVLYRIEKMFLQLLEIEEGWK---YRPPPPCFSEQQ--SNQVEKLFQTLKTQEQNNLEEAA--------------------------------DGFLQVLSVRKGKALVARLLPFLPQDQAVTILLA---ITHHLPLLVRRDVADQALQMLFKPLGKCISHLTLHELLQGLQG--------LTLLPPGSSERPVTVVLQNQFGISLLYALLSHGEQLVS-LHSSLEEPNSDHTAWTDMVVLIAWEIAQMPTASLAEPLAFPSNLLPLFCHHVDKQLVQQLEARMEFAWIY-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAC4-1", "uniprot_id": "E7FAC4_DANRE", "id": "E7FAC4-1", "name": "", "aln": "-----------MGDSEDPEKNREPIPDAVWPENGD-----QWSDKGEDDECGLLQEMAEEDEEIDLYNEETFGLDEAVNGDTPDIDPTDLLLLSSDSSPTPQSSHPPPPPPPPPLPPKSPFTYSTHCPPRPEPHSWPHTPTGRSQRGRGGRGQLFDDPAVVKTVKGRPSLKSIDSAIVDCSLSTYWEDLNSNSWMVA----------PLKSSRSPAQTILQDQAIVGVIDRSAHGRVPPVSPNFLSPMRPFSTSRGRRGQPFVGSFNQRCHYQAQKTPMAPCPVFRPQRLFSPQQQYNQPGGFMS---------------------------------------PSRPPLSTSMPR----------------------------------TPKLMHLRFGTDSPRPAPFYSPSASIMQGLRAPGPVVQFHP----------------QHKRLLSQRQ-----------PRPHKKPLSWD---------------------PYSQIMSDKEKEWIIRLQMIQLQSENPHLDDYYYQEYYQRMETKL-------------------------------------AEEEYVGDRTKKEPPKLTTPYVSKNV---------SYIPVVHIEGSLGQVAVSTCFS-PRRAIDAVHAS--------------------------THDEHKDTRQ-QRLEVLSTIEKLYLILLEVEEAEK---VKTTVSDKEEESRLMQNMKRKVEQLYNELRCTNLDSG--------------------------------EEFLSCLLVSKGKRLVARLLPFLSHDSALHILST---VTKHLPVLMSRDT-DEALPILYPSLRAVINGLVFSQLIRILKE--------FTALLPDSQDTRLTLACQNKFGLSLLYALLSQGERLLS-SDLPMEPSIGDFETWTDTVFHVARQLSQT---SLVEPLLLPSNLLTLFCRYLDKRTVHQLKNNMESATGYLAVAS--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEN9-1", "uniprot_id": "Q9VEN9_DROME", "id": "Q9VEN9-1", "name": "", "aln": "MDDSFFGFDTNLPDEDGGDGRIVEAEYDALNDETFGSAINGDWEEAHETMVRLGGNGERVRKRPAESSGNTDFADQGNGAFLRHANPLSSAPSSSGSTPAPLNAPFRQSRHIGDSDLELNISSMKLDDMDLSSFTTDSEAGGLSNRIKLDSGVWGSQPFPNNQHLFREPMRSAFKPQQQQHQQHQPQQMKPPQEANANFALNPQPFPKITTLEDIERNMIIQQAIPKQQQQSQQQAERKMFDDFSLGNRQQVPTPTMLQQQMLQQQHHQKQQSQQQPPQQAQHKVPPGFLGTPHTSPPRPNLGFPGPELLPTPSSQQQLNGIGGNRVPPGFIYPQGLPGNIPQLPQHPLMQQHMPHNFPLPGGNQRPLPNPQALPTALNNFAMHPSFNAMRAAGIHPGAFMQPPHPHQMLPPRMPPHPLQAATSLLGQQPPNSMYNMFNMRLVQEIQQNHPLLQQAAVVRQMQQSRAGSVASDRQRSQAQQQQQGRRPDGTGNYPLEEYDEYANLMSTRDKHWLIGIQLSQLNTDTPYIDDYYYTVFRERKAQQNGQMRNSQAHKDNQLNHPLTQPRGHAQLILVQLGNKNGTRNGHGRERRNSENTNSTSGNTNNGSGGNNNNLTGYIFSPLKFENSLGKLQYGSVTA-PRKIIDADIMSGESNAAAEANATSSS--KSSTPLPTSASHDVNPSSMRKSRHILLLIETLYRYLLKLEDLESPEVMATIELKKKKEAERIAALEQLEMANKTPEERAAEAANPQTMNPQLKNKFNYEVETKAALVNKLKAGLAFDKVIAMMNVRKGKILIRRIMPFIADQSIRWVVWSGVFCSLQTVVKKDKDDVEGVLYALYPEFKKHVNKATFELLVSISSA--------ITLN-----DKKLAGIFCSRFGILSLVALILRAEEIYV-SRTDATLSEENRQKWREFLAQVASCLNRTIQNQTIS-AAIESDAIQPLMDHFERFKDLKLDALLALITEARHQID--------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25644-1", "uniprot_id": "PAT1_YEAST", "id": "P25644-1", "name": "Deadenylation-dependent mRNA-decapping factor PAT1", "aln": "--MSFFGLENSGNARDGPLDFEESYKGYGEHELEEN---DYLNDETFGDNVQVGTDFDFGNPHSSGSSGNAIGGNGVGATARSYVAATAEGISGPRTDGTAAAG---------------------------------------------------------------------------------PLDLKP------------------------MESLWSTAPPPAMAPSPQSTMAPAPAPQQMAPLQPILSMQDLERQQRQMQQQFMNFHAMGHPQGLPQGPPQQQFPMQPASGQPGPSQFAP---------------------------------------PPPPPGVN-------------------------------------------------VNMNQMPMGPVQVPVQASPSPIGMSNTPSPGPVVG----------ATKMPLQSGRRSKRDLSPEEQRRLQIRHAKVEK-------------------ILKYSGLMTPRDKDFITRYQLSQIVTEDPYNEDFYFQVYKIIQRGGITSESNKGLIARAYLEHSGHRLGG----------RYKRTDIALQRMQSQVEKAVTVAKERPSKLKDQQAAAGNSSQDNKQANTVLGKISSTLNSKNPRRQLQIPRQQPSDPDALKDVTDSLTNVDLASSGSSSTGSSAAAVASKQRRRSSYAFNNGNGATNLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDD---------------------------SSYDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIILSSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIRNNNVSFLTTSKIGLNLITILISRAALIKQDSSRSNILSSPEISTWNEIYDKLFTSLESKIQLIFPPREYNDHIMRLQNDKFMDEAYIWQFLASLALSGKLNHQRIIIDEVRDEIFATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFLNVMGLVYRDGEISELK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: : : . : . : . . : . * * * : . . . * : : . : *: :*: ::*.:: *: *: : * :*:*: : : : . : .: . : : **:: **: :: : . : . ::. :. . . :.. . : .: : . ** :: *:: *: :. :: : : . * : : :: : : :: .::*: : *: :. : . : * : : : ", "identical_positions": 24, "similar_positions": 105, "identity": "2.26%" }, { "cls_id": "homologset.agr.HGNC:33631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTZ1-1", "uniprot_id": "E9PTZ1_RAT", "id": "E9PTZ1-1", "name": "Platelet endothelial aggregation receptor 1", "aln": "---MPLCP-LLLLALGLRLAGTLNSNDPNVCTFWESFTTTTKESHLRPFSLPPAESCDRPWEDPHTCAQPTVVYRTVYRQVVKMDSRPRLQCCGGYYESSGACVPLCAQECVHGRCVAPNRCQCAPGWRGDDCSSECAPGMWGPQCDRLCLCGNSSSCDPRSGVCFCPSGLQPPDCLQPCPDGHYGPACQFDCHC-YGASCDPRDGACFCPPGRTGPSCNVPCSQGTDGFFCPRTYPCQNGGVPQGSQGSCSCPPGWMGVICSLPCPEGFHGPNCTQECRCHNGGLCDRFTGQCHCAPGYIGDRCREECPVGRFGQDCAETCDCAPGARCFPANGACLCEHGFTGDRCTERLCPDGRYGLSCQDPCTCDPEHSLSCHPMHGECSCQPGWAGLHCNESCPQDTHGAGCQEHCLCLHGGVCLADSGLCRCAPGYTGPHCANLCPPNTYGINCSSHCSCENAIACSPVDGTCICKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEGVCSPQTGACTCTPGWRGVHCQLPCPKGQFGEGCASVCDCDHS--DGCDPVHGHCRCQAGWMGTRCHLPCPEGFWGANCSNACTCKNGGTCVPENGNCVCAPGFRGPSCQRPCPPGRYGKRCVP-CKCNN--HSSCHPSDGTCSCLAGWTGPDCSESCPPGHWGLKCSQPCQCHHGATCHPQDGSCVCIPGRTGPNCSEGCPSRMFGVNCSQLCQCDPGEMCHPETGACVCPPGHSGAHCKVGSQESFT------IMPTSPVIHNSLGAVIGIAVLGTLVVALVALFIGYRHWQKGKEHEHLAVAYSTGRLDGSDYVMPDVSPSYSHYYSNPS---YHTLSQCSPNLP--PPN-----KIPGSQLFVSSQASERPNR-NHGRDNHATLPADWKHRRES----HDRGTSHLDRRYSCSYGHRNGPGPFCHKGPISEEGLGASVMSLSSENPYATIRDLPGLPGEPRESSYVEMKGPPSVSPPRQPLHLRDRQQQ-QLQSQRDSGTYEQPTPLSRNEESVGSMPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPSRRQDR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIK5-1", "uniprot_id": "PEAR1_MOUSE", "id": "Q8VIK5-1", "name": "Platelet endothelial aggregation receptor 1", "aln": "---MPLCP-LLLLALGLRLTGTLNSNDPNVCTFWESFTTTTKESHLRPFSLLPAESCHRPWEDPHTCAQPTVVYRTVYRQVVKMDSRPRLQCCRGYYESRGACVPLCAQECVHGRCVAPNQCQCAPGWRGGDCSSECAPGMWGPQCDKFCHCGNNSSCDPKSGTCFCPSGLQPPNCLQPCPAGHYGPACQFDCQC-YGASCDPQDGACFCPPGRAGPSCNVPCSQGTDGFFCPRTYPCQNGGVPQGSQGSCSCPPGWMGVICSLPCPEGFHGPNCTQECRCHNGGLCDRFTGQCHCAPGYIGDRCQEECPVGRFGQDCAETCDCAPGARCFPANGACLCEHGFTGDRCTERLCPDGRYGLSCQEPCTCDPEHSLSCHPMHGECSCQPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGLCLADSGLCRCAPGYTGPHCANLCPPDTYGINCSSRCSCENAIACSPIDGTCICKEGWQRGNCSVPCPLGTWGFNCNASCQCAHDGVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASVCDCDHS--DGCDPVHGQCRCQAGWMGTRCHLPCPEGFWGANCSNTCTCKNGGTCVSENGNCVCAPGFRGPSCQRPCPPGRYGKRCVQ-CKCNNN-HSSCHPSDGTCSCLAGWTGPDCSEACPPGHWGLKCSQLCQCHHGGTCHPQDGSCICTPGWTGPNCLEGCPPRMFGVNCSQLCQCDLGEMCHPETGACVCPPGHSGADCKMGSQESFT------IMPTSPVTHNSLGAVIGIAVLGTLVVALIALFIGYRQWQKGKEHEHLAVAYSTGRLDGSDYVMPDVSPSYSHYYSNPS---YHTLSQCSPNPP--PPN-----KVPGSQLFVSSQAPERPSR-AHGRENHVTLPADWKHRREP----HERGASHLDRSYSCSYSHRNGPGPFCHKGPISEEGLGASVMSLSSENPYATIRDLPSLPGEPRESGYVEMKGPPSVSPPRQSLHLRDRQQR-QLQPQRDSGTYEQPSPLSHNEESLGSTPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPSRRQDR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VY43-1", "uniprot_id": "PEAR1_HUMAN", "id": "Q5VY43-1", "name": "Platelet endothelial aggregation receptor 1", "aln": "-MSPPLCP-LLLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHS--DGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVP-CKCAN--HSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFT------VMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRHWQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPS---YHTLSQCSPNPP--PPN-----KVPG-PLFASLQNPERPGG-AQGHDNHTTLPADWKHRREPPPGPLDRGSSRLDRSYSYSYS--NGPGPFYNKGLISEEELGASVASLSSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQFWDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPLRRQDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8N2-1", "uniprot_id": "E7F8N2_DANRE", "id": "E7F8N2-1", "name": "", "aln": "MKTAEICVVLFVLGCVCELSLSLDPRDPNVCSLWESFTTSVKESYAQPFDQMSEEPCSEPWS-ANKCTRHRITYKTLYRQVVKMDYRRRYQCCPGFYESRNKCVPRCTKECVHGRCVAPDRCQCEMGWRGDDCSSSCDGQHWGPGCRRLCECQNGGECDVLTGNCQCPAGYTGQHCHDPCPVKWFGQGCRQECQCGTGGICNQTTGECVCKQGFTGTLCEESCPRPKR---CAARCPCQNGGICQG-NGVCLCPPGWMGPVCTERCPPGRFGINCSKDCLCHNGGHCDQEKGQCQCDAGYTGERCNEECPVGTYGEDCKGVCDCANGARCYNIHGGCLCEPGFKGPRCDHRMCPEAVFGMHCQHRCLCNPLNTLSCHPLKGECTCQPGWAGLYCNETCAQGYYGNGCLEPCLCVNGGVCDSVTGQCHCPPGFTGLHCEKLCEDGFYGKGCLSACKCVNSIVCSPVDGACICKEGWRGPDCSIACSEGTWGPGCNRTCKCTNGASCDPADGSCKCTAGWRGASCDEPCLIGTFGPGCQNQCDCVHD--EGCESVTGQCLCLPGWTGVRCTQQCPEGTWGIQCNQTCSCLNSATCQAHTGTCLCKPGFWGAQCQHMCSAGLFGEKCSRHCPPCVH-ASSCHHITGDCQCLSGYTGPLCEQACPVGRYGSHCSNVCRCTNNATCHHEVGLCICPAGWTGSDCSLLCQAGTFGINCAQTCSCPPNHSCDPHNGDCVCEPGP-GEACKP-EQELSV------MVPVSPVERDSWGAIAGIVVLVILVVLLLAVLLLYRRRQQDKQSNTPVVSFSSTRTVSSEYAVPDVPHSYHHYYSNPS---YHTLSQNRPPLPHLPNNQDRAIKNTNNQLFCSLKNMERERRGLFTADTNATLPPGWKHQEPP----KDPGAFGIDRSYSYSAT----LGKHYNK-ELKDSCVAVSSSSLNSENPYATIKDLPGLPVCPPESSYMEMKS----AVPRQ-----------RSYTQIISPPLMTAPALPCTGHCSLSNAEEQE--LQNHYDLPINSHIPGHYDLPPVRRPPSPSPRRLPN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0A0-1", "uniprot_id": "DRPR_DROME", "id": "Q9W0A0-1", "name": "Protein draper", "aln": "--MLPVILIACLAQLVLAQADLKDLDGPNICKRRELYNVDVVYTELQSFQERGSTWCV---TFPPRCSTYRIKHRVVNKTKTIAKNRIVRDCCDGYIASAGECVPHCSEPCQHGRCISPEKCKCDHGYGGPACDINCPPGWYGRNCSMQCDCLNNAVCEPFSGDCECAKGYTGARCADICPEGFFGANCSEKCRCENGGKCHHVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGACMCNPGWTGDVCANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMTCDCANDAMCDRANGTCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSAQCTRPCTFLRYGPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCDCQNGAKCEPETGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTGERCERKCDTGKFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVCRCLNNSSCDPDSGNCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYIGLTCEHPCPAGLYGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVHHKVCRKADGMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHGCVCRSGYTGDNCDELIASQRIADQSENSSRASVALTLVLMTLFACIIFAVFIYYRRRVSNLKTEIAHVHYTHDTNPPSWPPN-----HNFDNPVYGMQAETRLLPNNMRSKMNNFDQRSTMSTDYGD-----DCNASGRVGSYSINYN----HDLLTKNLNADRTNPIVYNESLKEEHVYDEIKHKEGYK-DPDEYDHLDYSRPSTSQKPHYH----------RMNDAMLNINQDEEKPSNVKNMTVLLNKPLPPTEPEPQHECFDNTNTN--LDNVSTASPSSSPKFLK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IP58-1", "uniprot_id": "Q8IP58_DROME", "id": "Q8IP58-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIREKLFGKLLLLLAMVLPLGSGQNSTLKINTN--VKDIEAGVVALPSIQG------------------------------PGNICIREEPYVEHVQVPEMQP-------------VRVRTSSWCMEIPPRCATFK--------------------TEMREVMRVQKLNKTRTVRFCCQGYEGNLSDSQAT-------CKPICRGGCGRGSCVMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNLCQCQNGAACDNKSGLCHCIAGWTGQFCELPCPQGTYGIMCRKACDCDEK---PCNPQTGACIQQD--------QPLQLNVSHVIVETVNSTLEKMGIIPRPTTPVPLP---------------------------------------EVIVIKQPTSNENAQHSPKIIVHQSSSDLLENLHTAAAAGVPTPEVIHVITNGITSPQEHLAGFVGG----EANSSQTATADHQSGLVVT--------------------------------------LVSIMLLLLVAIAVGSLYVYRRYHHKNAAVYNANGTVTTLPAN-PEVVLTEAAVLGKNFHEPLP------------EPP---------------VAFAVTPQSNEAQPELYDSPSNNSSIKTPPYAYAR-----------KESLYSVVSP---------------KSRKGSLDSHLYDEIRYHQQHHHQQHHPRSHQH----------------------------VQHSTTASQFLPARPQIMPANDQFSNGSVHPHQRSHHVTHLIIPPQNSNFLQVPAQITAKRVAHL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . * . . .. . . . .. * . *: : : .: : * .* . * *: * . . . * * . . . * * *: .* * . :* .* *.* : . *. * * * .** * *: * * :* * . *:* . *:. * * . . . : . . : . . . .* . . : . . .* . * . . . * : : : * .:. : : : . . . * : . .: ** * .* * :. . : . : . .. ... ", "identical_positions": 48, "similar_positions": 94, "identity": "4.51%" }, { "cls_id": "homologset.agr.HGNC:33632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZV4-1", "uniprot_id": "A0ABK0LZV4_RAT", "id": "A0ABK0LZV4-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MEEVIAGLQGFTFTFEQDVELQRGTGLLPFQGMDKSSSAVCNFFAKG----LCVKGMLCPLRHEQ--GEKMVVCKHWLRGLCRKSDCCNFLHQYDVSRMPVCYFHSKFGNCNNK-ECPFLHLKPVPKLQDCPWYDQGFCKEVGPLCKYRHVHQVLCPNYFIGFCPKGP-KCQFGHPKMSPILHRSN-------------------------------MKPINQLWDSTTSTGNT---------LVPHSQAKATVHHQKRWS----LPP--------ACSSRAHLAP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UWW6-1", "uniprot_id": "G3UWW6_MOUSE", "id": "G3UWW6-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MEEVIAGLQGFTFAFELDVESQKGTGLLPFQGMDKSSSAVCNFFAKG----LCVKGMLCPLRHEQ--GEKLVVCKHWLRGLCRKSDCCDFLHQYDVSKMPVCYFHSKFGNCSNK-ECLFLHLKPVLKLQDCPWYNQGFCKEVGPLCKYRHVHQVLCPNYFTGFCPEGP-QCQFGHPKMSPPFHPSNVK-----------------------------LQPVNQPWDSTTSTGNT---------LVSPFQAKPMVHGQRRWS----LPQ--------ACSSRAHPAP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMK7-1", "uniprot_id": "CPS4L_HUMAN", "id": "A6NMK7-1", "name": "Putative cleavage and polyadenylation specificity factor subunit 4-like protein", "aln": "MQEVIAGLERFTFAFEKDVEMQKGTGLLPFQGMDKSASAVCNFFTKG----LCEKGKLCPFRHDR--GEKMVVCKHWLRGLCKKGDHCKFLHQYDLTRMPECYFYSKFGDCSNK-ECSFLHVKPAFKSQDCPWYDQGFCKD-GPLCKYRHVPRIMCLNYLVGFCPEGP-KCQFAQ-----------------------------------------------KIREFKLLPGSK---------I-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPT8-1", "uniprot_id": "CPSF4_DROME", "id": "Q9VPT8-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MDILLANVSGLQFKAERDLIEQVGAIPLPFYGMDKSIAAVCNFITRNG--QECDKGSACPFRHIR--GDRTIVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSRFNACHNK-ECPFLHIDPQSKVKDCPWYKRGFCRH-GPHCRHQHLRRVLCMDYLAGFCPEGP-SCKHMHPHFELPPLAELGKDQLHKKLPTCHYCGELGHKANSCKQYVGSLEHRNNINAMDHSGGHSGGYSGHSGHIEGADDMQSNHHSQPHGPGFVKVPTPLEEITCYKCGNKGHYANKCPKGHLAFLSNQHSHK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06102-1", "uniprot_id": "YTH1_YEAST", "id": "Q06102-1", "name": "mRNA 3'-end-processing protein YTH1", "aln": "MSLIHPDTAKYPFKFEPFLRQEYSFSLDPDR-------PICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPECVFFSKNGYCTQSPDCQYLHIDPASKIPKCENYEMGFCPL-GSSCPRRHIKKVFCQRYMTGFCPLGKDECDMEHPQFIIPDEGSKLR-----------------------------IKRDDEINTRKMDEEKE-------------RRLNAIINGEV---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : .. * * : : . * .:*:* * :* ** :* :. :**:*******:*.* *.:**:*:: :** * *.*: . * :. :* :**:.* * .* *. *** *. * :*: :::* *: **** * .*. : : ", "identical_positions": 53, "similar_positions": 46, "identity": "17.49%" }, { "cls_id": "homologset.agr.HGNC:3364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35795-1", "uniprot_id": "ENTP2_RAT", "id": "O35795-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 2", "aln": "MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHR-------FHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAA---LVLLLRQVRSAKSPGAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55026-1", "uniprot_id": "ENTP2_MOUSE", "id": "O55026-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 2", "aln": "MAGKLVSLVPPLLLAAVGLAGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVRGGGISSYANDPSRAGQSLVECLEQALRDVPKDRYASTPLYLGATAGMRLLNLTSPEATAKVLEAVTQTLTRYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPDNEVHLRLYGQHYRVYTHSFLCYGRDQVLQRLLASALQIHR-------FHPCWPKGYSTQVLLREVYQSPCTMGQRPQTFNSSATVSLSGTSNAALCRDLVSGLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLKTVMGLPVGTLKQLEDATETTCNQTWAELQARVPGQQTRLPDYCAVAMFIHQLLSRGYRFDERSFRGVVFEKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAA---LVLLLRQVRSAKSPGAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5L3-1", "uniprot_id": "ENTP2_HUMAN", "id": "Q9Y5L3-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 2", "aln": "MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHG-------FHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAA---LVLLLRQVHSAKLPSTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWQ3-1", "uniprot_id": "A0A8M3AWQ3_DANRE", "id": "A0A8M3AWQ3-1", "name": "apyrase", "aln": "MDKLFVKFVASGSLLLFGIVSILLLTVSIHEIREPAQYMYGIVLDAGSSHTALYVYKWPADKLNGTGVVTQHSECHVKGGGISGYAGQRGAAGRSLELCLKQAVLDIPPHRHHLTPVYLGATAGMRLLKLSNPYKASQVLQEVKETIKSFPFSFRGAVILSSQDEGVYGWVTVNYLLENFIKYGYVGRWLNSGRKTVGALDLGGASTQITFETPERVESELNHMTLRLFGHEYSLYTHSYLCYGKEEALRMILAYLITSQDYTSTSKMYHPCYPSDFINAFRLKEVFDSPCTASWRPKPYNPHSHITVQGTGDYQSCLGNTSKIFSFKSCSFSQCAFNGVFQPNISGGFMAFSAYYFTHSFLQQITEMKISTYAQLEEATQAVCNMTITEMTMKAPDLKKYLKDYCAVAVYIQVLMLRGYNFDENSFQNVAFQKKAGEASVGWALGYILSVSSLLPEESAAIRKGLCPAAWTGLMFLISVLLTATFCYMVLLVIQRRKSKEDVS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UUT2-1", "uniprot_id": "A0A8N7UUT2_DANRE", "id": "A0A8N7UUT2-1", "name": "apyrase", "aln": "MQLQTCTIIAG---LFVSFVGILLLVVNTEDFKEPAQLMYGIVLDAGSSHTSMFIYKWPADKQNGTGIVSQHSECRVKGGGISSYAGIKGAAARSLEECMDKATKSIPKSRQRITPVYLGATAGMRLLNISKPKESAEVLKEVGEKLKSYPFSFKGASILTGQDEGAYGWITVNYLLENFIKYGFVGQWITPGRDTVGALDFGGASTQITFVTKQTVENKDDLMKLRLYGRDYQIYTHSFLCYGQDQALLRLLAHLITTQG--SDTSIIHPCYPADYSSSIKLGSVFDTPCVK--RQTPYKPDDELQIKGTGNYNQCLGNVSQLFSFSSCSYSKCSFDGVFQPNITGNFMAFSAFYYIHQFLQKAAGITITSPADLEHAAQFVCNMSFQQMQNKFPTEGDHLRDYCADSVLMRVLLINGYGFSDLSFPHISFQEKVEDTSVGWSLGYMLSLSNLLDAENAMVRKALCPDAWRAAVLLFSVLVIAS-LFFLLRSYQKNGTKLCCYI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .::. .:..:*** * .:.:**. ************::::******* *.**:* ***.* * *****.**. . *.:** *:.:* .:* * **:********* ::::.* :: ** * ..:. :**.*:** **:.*:**.:**:*.***********:**:*: . : *:**:*:********* * . *. . : *:*:*:.* :****:****::: * :** : : ***:* .: . . * .*:::**. * :: : :.*:.: * . .* :*.:.**.:*:*:*:***** ::*.*:****::: .** : : : :** *: .** : :: : * * **** :: :: *: .** *.: :* : *::*. :::***:***:*.::.*: : . :**. :* ::*:: : *: ::* * . :* ", "identical_positions": 186, "similar_positions": 162, "identity": "36.83%" }, { "cls_id": "homologset.agr.HGNC:3365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFW6-1", "uniprot_id": "ENTP3_MOUSE", "id": "Q8BFW6-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 3", "aln": "---MFTVMTRQPCEQAG-FRALSRTPAIVTLVVLLVSIVVLVTLTLIQIRHPQVLPPGLKYGVVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCILKVKEQVPEHLHGSTRIYLGATAGMRLLRLQNETAAREVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVAGEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGQNEAEKKFLAMLLQSPSTEANISNPCYPQGYSTAFTLGHVFGSLCTEKQRPESYNSSKSVTFMGTGDPRLCREKVASVFDFNACQEQDACSFDGIYQPKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPALLSRFDETYARSYCFSAHYIYHLLVNGYKFTEETWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIHLPIQPPVFMGVLAFFTAIALLCLAFLLYLCSSFRTKERSENAFDQAVDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5S7-1", "uniprot_id": "A0A0G2K5S7_RAT", "id": "A0A0G2K5S7-1", "name": "apyrase", "aln": "RTTVLTSFTEIKEKIVSCFRALSRTPAIVTLVVLLVSIVVLVTLTLIQIHHPQVLSPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCMLKVKEQVPKHLHESTRVYLGATAGMRLLRLQNETAAHEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVSEEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGRNEAEKKFLAMLLQSPSTDANISNPCYPHGYSTTFTMGHVFGSLCTEKQRPKSYNPSDTITFTGTGDPQLCREKVASVFDFSACQEQDACSFDGIYQPKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPSLLPRFDETYARSYCFSAHYIYHLLINGYKFTEATWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIQLPIQPPVFMGVLAFFTAIALLCLAFLFYLCSAFRTKERSENAFDQAVDSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75355-1", "uniprot_id": "ENTP3_HUMAN", "id": "O75355-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 3", "aln": "---MFTVLTRQPCEQAG-LKALYRTPTIIALVVLLVSIVVLVSITVIQIHKQEVLPPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASALNLSGSFSLDTFNSSTWNFCSQNWSQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFFTAAALLCLAFLAYLCSATRRKRHSEHAFDHAVDSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* :*. : .. ::** ***:*::************::*:***:: :**.******:*******************************:*********** *****.*:***:*: *** ***.*** ** ::******************.**************************************:*******************:*****************: ***: *:** :*******.************:*************...*. :::*****:.** :**:****.**** .***:***... :** ***** **:*****:***.**::*::*****:****::************************ :**.*:*:** :.**:** **.:***.*********:*****::******* *****:************************** ****:***:****:*.****** ******** ****: * *.:**:***:*****", "identical_positions": 411, "similar_positions": 88, "identity": "77.11%" }, { "cls_id": "homologset.agr.HGNC:3367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6S9-1", "uniprot_id": "ENTP5_RAT", "id": "Q6P6S9-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 5", "aln": "----------------------------------------MATSWASVF-LLIIAYVGGTVFYREQQTWFEGVFLSSMCPVN-----------------------------------------------------VSAGTFYGIMFDAGSTGTRIHVYTFVQRTSGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEVAKDSIPRSHWKRTPVVLKATAGLRLLPEQKAQTLLLEVEEIFKNSP--FLVPDDSVSIMDGSYEGILAWVTVNFLTG--QLHGRGQETVGTLDLGGASTQITFLPQLEKTLEQTPKGYLASFEMFNSTFKLYTHSYLGFGLKAAR-----------LATLGALEAEGTDGHTFRSACL-PRWLEAEWIFGG-------VKYQYGGNQEGE---------MGFEPCYAEVRRVVQGKLHQPEE--IRGSS-FYAFSYYYDRAAETHL--------IDYEKGGVLKVEDFERKAREVCDNLESFSSGSPFLCMDLSYITALLKDGFGFEDGTLLQLTKKVNNIETGWALGATFHLLQSLGITS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUZ9-1", "uniprot_id": "ENTP5_MOUSE", "id": "Q9WUZ9-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 5", "aln": "----------------------------------------MATSWGAVF-MLIIACVGSTVFYREQQTWFEGVFLSSMCPIN-----------------------------------------------------VSAGTFYGIMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEVAKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSP--FLVPDGSVSIMDGSYEGILAWVTVNFLTG--QLHGRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAAR-----------LATLGALEAKGTDGHTFRSACL-PRWLEAEWIFGG-------VKYQYGGNQEGE---------MGFEPCYAEVLRVVQGKLHQPEE--VRGSA-FYAFSYYYDRAADTHL--------IDYEKGGVLKVEDFERKAREVCDNLGSFSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLLQSLGITS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75356-1", "uniprot_id": "ENTP5_HUMAN", "id": "O75356-1", "name": "Nucleoside diphosphate phosphatase ENTPD5", "aln": "----------------------------------------MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPIN-----------------------------------------------------VSASTLYGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSP--FLVPKGSVSIMDGSDEGILAWVTVNFLTG--QLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAAR-----------LATLGALETEGTDGHTFRSACL-PRWLEAEWIFGG-------VKYQYGGNQEGE---------VGFEPCYAEVLRVVRGKLHQPEE--VQRGS-FYAFSYYYDRAVDTDM--------IDYEKGGILKVEDFERKAREVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHLLQSLGISH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8A7-1", "uniprot_id": "E7F8A7_DANRE", "id": "E7F8A7-1", "name": "nucleoside diphosphate phosphatase", "aln": "-------------------------------MSQQMLHLTLVSMWLFAGYFLAEATYYNHHMYNRYRAINHNANMDNQLPPEEPVVMEPVAP----------------------------------------RQVNFSRVFYGIMFDAGSSGTRIHIYKFIQKDPVELPVLDNEMYHAVKPGLSAYADMPEKGGESIVQLLKVAKKTIPKEQWIQTPVVLKATAGLRLLPEEKAKALLNEVKEVFDDSP--FFVPNNSVTIMNGINEGVLAWVTVNFLTG--HLYSKTKRTVGILDLGGGSTQITFLPRLKKTVQSAPSDYIAKINMFNSTYELYTHSYLGNGVFASR-----------LATLGALGADGLEWKVFRSSCL-PKKFSEEWSFGG-------LTYKVSGTPDGY---------AGYKLCYQEVLQVVKGIVHQPFE--VKGSSIFYAFSYYYDRAVESGL--------IDGSRGGTVEVRDFKKKAKEVCNKMTKYRPISPYLCMDMTYITCLLKDGFGFKDSTVLQLAKKVNNVETSWALGAIFDHFHNFSIQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T969-1", "uniprot_id": "A0AB32T969_DANRE", "id": "A0AB32T969-1", "name": "nucleoside diphosphate phosphatase", "aln": "----------------------------MNLLYPAPLSAALADLGQMVMKMMMFWLLPVWTLLLLSSSASSSSPPSSSAAADFSVRFGHTLPSLS-------------------------------------RPANSTQIFYGIMFDAGSTGTRIHVYTFIQREPDGLPVLDNEMFHSMKPGLSAYADMPEIAGHTVRQLLRVAKKTVPPLEWKRTPLVFRATAGLRLLPAAKAHALLEEVQDVFDESP--FYVPPDSVRIMNGTSEGILAWVTVNFLTG--RLERNTEKTVGILDLGGGSTQITFLPKSKKTIEAAPPDYISRFQMFNCSYQLYTHSYLGNGIKAAR-----------LSALGALNADGLEKKLFRSSCL-SRSHTAEFSFGG-------VSYHVSGDISGV---------RGYKACYQELVKVVKGIIKQPLE--LRDSSSFYAFSYYYDHAVEAGL--------IDEQRGGAVKVRDFRKTARQVCNRPARHTQLNQFLCMDLTYITCLLKDGFGFKESTVLQLTKKVRNVETSWALGAAIDHFQKSRIH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PBV2-1", "uniprot_id": "M9PBV2_DROME", "id": "M9PBV2-1", "name": "nucleoside diphosphate phosphatase", "aln": "MTNTDVRKRKLATDEKPPRRKSSGSPNASSGGNRGPSGLKISFLCLIISVILLLFVFGVYHLYYVKDEVPKVVLTKTSDFPTVTVPYAHVEPHFAPPVRRVITKKPIANKPTTDNDAGFVSENASPYLARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAFIPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSE--FSVDMDAVEIMDGTDEGIFSWFTVNFLLG--RLSKTN--QAAALDLGGGSTQVTFSP-TDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAAR-----------HAVFTHGYKK--EDTVLESVCVNPIIANRTWTYGN-------VQYKVSGKENGKSS--AEQPIVDFDACLELVKSKVMPLVKPKPF--TLKQHAVAAFSYYFERAIESGL--------VDPLAGGETTVEAYRKKAQEICAIPNDEQ---PFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVLTSDEKFSNS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32621-1", "uniprot_id": "GDA1_YEAST", "id": "P32621-1", "name": "Guanosine-diphosphatase", "aln": "-------------------------MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKTPEDISILPVNDEPGYLQDSKTEQN------------------------YPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSP--PTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ::****:*:*: *.* * * :. :****:: . ...:: ** * :* **:..:******** *: :* *.: : .. * ..* **.* **:::*.*.*:* * .. :****.***:.* * . : . . . :: .*:** *: .* . . : * *: . : : . .* . . . : . ***::::: : :: . ... . .:*:*::: **: *:.: :: **: . * .*.**. : ", "identical_positions": 75, "similar_positions": 101, "identity": "13.18%" }, { "cls_id": "homologset.agr.HGNC:3368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U0P5-1", "uniprot_id": "ENTP6_MOUSE", "id": "Q3U0P5-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 6", "aln": "-----------------------------MRKIPNHGTLRMTKVAYPLGLCVGLFIY-----------------------------VAYIKWHRASAAQAFFTIAGAASG----------ARWTQQAFSSPGSAARGHEVFYGIMFDAGSTGTRIHVFQFARPPGE-TPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASP--FLVGDDCVSIMNGTDEGVSAWITVNFLTG--SLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTYKLYSYSYLGLGLMSARLAILGGVEGKPAEND----------KELVSPCLSPRFRG--------EWEHAEVTYRISG--------QKAVG-LYELCASRVSEVLRNKVHRT----EEAQHVDFYAFSYYYDLAASFGLIDAEKG------GSLVVGDFEIAAKYVCRTL--ETQPPSSPFACMDLTYISLLLHE-FGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ER31-1", "uniprot_id": "ENTP6_RAT", "id": "Q9ER31-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 6", "aln": "-----------------------------MRKIPNHGTLRMTKVAYPLGLCVGLFIY-----------------------------VAYIKWHRASAAQAFFTIAGAASG----------VRWTQQAFSSPDSATRGHEVFYGIMFDAGSTGTRIHVFQFARPPGE-TPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASP--FLVGDDCVSIMNGTDEGVSAWITVNFLTG--SLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDD----------KELVSPCLSPRFRG--------KWEHAEVTYRISG--------QKAVG-LYELCASRVSEVLRNKVHRT----EEAQHVDFYAFSYYYDLAASFGLIDAEKG------GSLVVGDFEIAAKYVCRTL--ETQPPSSPFACMDLTYISLLLHE-FGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75354-1", "uniprot_id": "ENTP6_HUMAN", "id": "O75354-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 6", "aln": "-MKKGIRYETSRKTSYIFQQPQHGPWQTRMRKISNHGSLRVAKVAYPLGLCVGVFIY-----------------------------VAYIKWHRATATQAFFSITRAAPG----------ARWGQQAHSPLGTAADGHEVFYGIMFDAGSTGTRVHVFQFTRPPRE-TPTLTHETFKALKPGLSAYADDVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKKVFKASP--FLVGDDCVSIMNGTDEGVSAWITINFLTG--SLKTPGGSSVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTALRMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDG----------KELVSPCLSPSFKG--------EWEHAEVTYRVSG--------QKAAASLHELCAARVSEVLQNRVHRT----EEVKHVDFYAFSYYYDLAAGVGLIDAEKG------GSLVVGDFEIAAKYVCRTL--ETQPQSSPFSCMDLTYVSLLLQE-FGFPRSKVLKLTRKIDNVETSWALGAIFHYIDSLNRQKSPAS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PBV2-1", "uniprot_id": "M9PBV2_DROME", "id": "M9PBV2-1", "name": "nucleoside diphosphate phosphatase", "aln": "MTNTDVRKRKLATDEKPPRRKSSGSPNASSGGNRGPSGLKISFLCLIISVILLLFVFGVYHLYYVKDEVPKVVLTKTSDFPTVTVPYAHVEPHFAPPVRRVITKKPIANKPTTDNDAGFVSENASPYLARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAFIPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSE--FSVDMDAVEIMDGTDEGIFSWFTVNFLLG--RLSKTN--QAAALDLGGGSTQVTFSP-TDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAARHAVFTHG---YKKED----------TVLESVCVNPIIANR-------TWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKP----FTLKQHAVAAFSYYFERAIESGLVDPLAG------GETTVEAYRKKAQEICAIP--NDE---QPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVLTSDEKFSNS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32621-1", "uniprot_id": "GDA1_YEAST", "id": "P32621-1", "name": "Guanosine-diphosphatase", "aln": "----------MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKT-----------------------------PEDISILPVNDEPGYLQDSKTEQN----------YPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSP--PTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :. : : :. . : : : * ::******:*: ::* .* .* *. :****:: : .*:.: **. * :* . ..**:.:********* *:.::*. *:. : . * * *.**.* :**: :*:* *:* * . . .. :********:.* * : : ... .:: .*:** ** .* : ::. * * *: * . : : .. . : . :. : . ***::: : *: . . . . . .. : ... *:**:: **: :.: : :: :** . * .*.**. : : : ", "identical_positions": 83, "similar_positions": 123, "identity": "14.59%" }, { "cls_id": "homologset.agr.HGNC:33699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CWU5-1", "uniprot_id": "KHDC3_MOUSE", "id": "Q9CWU5-1", "name": "KH domain-containing protein 3", "aln": "MASLKRFQTLVPLDHKQGTLFEIIGE-PKLPKWFHVECLEDPKRLYVEPRLLEIMFGKDGEHIPHLESMLHTLIHVNVWGPERRAEIWIFGPPPFRRDVDRMLTDLAHYCRMKLMEIEALEAGVERRRMAAHKAATQPAPVKVREAAPRPASVKVPETATQPAPVKVREAAPQPAPVQEVREAAPQQASVQEEVREAATEQAPVQEVREAATEQAPVQEVSEAATEQAPVQEVNEAATEQASVQAVREAATRPAPGKVRKAATQPAPVQVCQEATQLAPVKVREAATQPASGKVREAATQLAPVKVRKAATQLAPVKVHEAATQPAPGKVSDAATQSASVQVREAATQLSPVEATDTSQLAQVKADEAFAQHTSGEAHQVANGQSPIEVCETATGQHSLDVSRALSQKCPEVFEW-ETQSCLDGSYVIVQPPRDAWESFIIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVV1-1", "uniprot_id": "KHDC3_RAT", "id": "D3ZVV1-1", "name": "KH domain-containing protein 3", "aln": "MATLKTFRTLVQLKHKLGKAYEIVGE-PRLPKWFHVEYLEDPKKMYVEPTLVEIMFGKDGEHIPHVECTLHVLIHVNVWGPEKQAEILIFGPPNFQKDVAQMLSNVAHFCRMKLMEKEALEAGVERRLMAASKATTQPTPVKVRDAATQVAPVQVRDAAIQPAPVKVRDAATQVAPVQ-VHEVATQPVPVQ--VRDAATQPVPVR-VRDAATQPVPVR-VRDAATQPVPVR-VRDAATQPVPVR-VRDAATEPVPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVREAATQQTPVEVADDTQLVQLKAGEAFAQHTSGKVHQDVNGQSPIEVCEGATQRHSVDASEALSQKCPEDLEGGDTETSLDDSYVIIRPSRAVWEPFVML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q587J8-1", "uniprot_id": "KHDC3_HUMAN", "id": "Q587J8-1", "name": "KH domain-containing protein 3", "aln": "MDAPRRFPTLVQLMQPKAMPVEVLGHLPKRFSWFHSEFLKNPKVVRLEVWLVEKIFGRGGERIPHVQGMSQILIHVNRLDPNGEAEILVFGRPSYQEDTIKMIMNLADYHR-------QLQAKGSGKALAQDVAT---------------------------------------------------------------------------------------------------------------------------QKAETQRSSIEVREAGTQRS-VEVREAGTQRS-VEVQEVGTQGSPVEVQEAGTQQSLQAANKSGTQRSPEAASKAVTQRFREDARDPVTRL---------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : * *** * : . *::*. *: .*** * *::** : :* *:* :**:.**:***:: : ***** .*: .*** :** * ::.*. :*: ::*.: * *:* . : :* *: :.* ** :.::* : .** : *:**:*.** : :*::..** :**:*:.*.** : ...:.** :* . .*.** :.*:..*: ", "identical_positions": 75, "similar_positions": 79, "identity": "16.97%" }, { "cls_id": "homologset.agr.HGNC:33700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C8N6-1", "uniprot_id": "NEMP2_RAT", "id": "P0C8N6-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "MPPGS--WWLVLWLPPLATLPAGAVPQEEAAMSVPRCKSLKETDLIKTSVSDCYCYNQHSQIEWTYMWSTVQVTVTSPGLLSIVYITGRHTCQHTETILSFLKCVTHNFWTAEEAKEVTIVFSPYGETVCFSVKPVGSLLTYAVSVNRNVVDFRLFLVFATGIFLFFYAKTLSQSPVFYYSSGTVLGILMTLVFVLLMTKKHIPKYSTFGALMIGCWFASVYVLCQLMENLKWLWCGNRIYVLGYVLVVGLCSFSACYSRGPPADEGSRDLLMWALRFLSLVLVYTGMAISQFAYAVMILLLLS----WTRHYLLRAFSCLRWKVRQWFATRALVVRYLTDDEYREQAEAETASALEELRQACCRPDFPSWLAVSRLQAPKKFAEFVLGASHLSPEEVSTHEK--QYGLGGAFLEEQLFSLQTESLPAS---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CB65-1", "uniprot_id": "NEMP2_MOUSE", "id": "Q8CB65-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "MLPRL--WWLVLWLQPLATLPASAVHDEEAAMSVPRCKSLKETDLIKTSVSDCYCYNQHSQIQWTYMWSTVQVTVTSPGLLNIVYITGSHNCQHTESILSFIKCVTHNFWAPEEAEEITIVFSPYGETVCFSVKPVGRLLPYIVSVSRNIVDFKLFLVFVTGIFLFLYAKTLSQSPVFYYSSGTVLGILMTLVFVLLMAKKHIPKYSTFGALMIGCWFASVYVLCQLMEDLKWLWYGNRMYILGYVVVVGLCSFAACYSHGPLADEGSRDLLMWTLRLFSLALVYTGVAAPQFAYAVLIVLLFS----WSLHYLLRAFSYLRWKMRPWFTAEPQVARYLTDDEYREQAEAATARALEELRQACCRPDFPSWLAVSRLQAPKKFAEFVLGASHLSPEEVSTHEK--QYGLGGAFLEEQLFSLQTDSLPAS---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFY4-1", "uniprot_id": "NEMP2_HUMAN", "id": "A6NFY4-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "MGPRQGRWWLLLWLPPLATLPVRG-EAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQVEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITIIINPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILLMSS----WSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRKPDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEE--QYGLGGAFLEEQLFNPSTA--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYC4-1", "uniprot_id": "NEMP2_DANRE", "id": "F1QYC4-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "-MEKLAAFILVLTLLCAYWQSAEG----IREYSYADCTDVKGDSAHRYSGSRCFCYSPGTVIKWKDIWSTFKVNVSSNVDVVVVFPMETINCHHPDDLLTVMNCFVEHYWPSTVQRETSLEIPLVDVDICFMIKSPRSNTEYTLHVSNKRLNRMCFLLFVCGLILFFGARNICRSSLFFYTTGVSLGIIATFVFLTLLLRNFVPKRGLFLVLLGAGSGLSYMGIQRVLNEWDDIVTEHWMELLAYVLISGLFSFAVCYKHGPITNKHTLNFMTCSMQAVGIVLLYYGITFPPAYFVLVAVLLCWKILPLAWSLLMGICSLFYSFLALFRRRRRPTVRLLTEEEYREQGEIHTRASLDELREYCNRPGFPAWETVLRLRSPQRFAEFLRQGSHITQEEHQNHEN--HYGLGGAYYENVIFNNSSSSDTQSHREEAEDNSEDEIVGNSPPVLNNLPSPTIYPPTICPYPPVTYTPQPEPLDPEDQDFF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXD6-1", "uniprot_id": "NEMP_DROME", "id": "Q9VXD6-1", "name": "Nuclear envelope integral membrane protein", "aln": "-MHSAGLLMLTVAGYFTSGIPGNTASSDVAYLTPGTYINLSEN-ILGLQTLRTFCYP-GKRLTVSSLFETVEFVLAIGSDD-----YSQYGGKTPEEVLQHYKDKQSLFSITLFAQKRQLLQLSPFEQQCIGISSRQ---AYTVILNSIPLDLWRLAQFAVGILILFSARRLAKNSVFYYLVGIVIGICASLLVVIYLAAKLFPRRTMMYGVLIGGWTIGFYVIKQLADNLRLILITYRDHVLGYLVITGLISFLICYRIGPPKNPRSQTIVMWVLQAIGAVMAYFSSWHTSAVIFIMVLVFVA------HYFPISWTNQIKFMYRRRFPLKR---RMLTQEEYEQQTAVETSKSLADLRKYVNSPECKQWAVMGKLRDPLRFASFANGAPHLDDEEIEDHSRTIEESMDAAPEEESVEEPEEDKPAELLPLPNSQFRYQQAARNSEPEPESESDDSEEEEFFEQEVDLRQVVQ------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : :. . :** . : . ::.*.:. :: : .: :* : : . .: : *: :.. * : :. :: : *. *::::: *: :.:.. *:* * :*: :::.: : . .*: : :: . . : :: :: : :*.*::: *: ** ** ** : : :: :: .. .: * . . : ::: : . : . : **::**.:* * :* :**. * * .: :*: * :**.* ..*: ** . *.. . .:..* *: : . . ", "identical_positions": 47, "similar_positions": 128, "identity": "9.67%" }, { "cls_id": "homologset.agr.HGNC:33701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43527-1", "uniprot_id": "CASP1_RAT", "id": "P43527-1", "name": "Caspase-1", "aln": "MADKVLRAKRKQFINSVSVGTINGLLDELLEKRVLNQEEMDTIKLANITVMEKARDLCDHVTKKGPRASQMFITYICNEDCYLAEILELQSGPSAETVFVTEDSKGGHPFSSETKEKLNKEGGAFPGPSGSLKFCPLEIAQKLWKENHSEIYPIMKTPTRTRLALIICNTDFQHLSRRVGADVDLREMKLLLQDLGYTVKVKENLTALEMTKELKEFAACPEHKTSDSTFLVFMSHGLQEGICGITYSNEVADILKVDTIFQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVGNSEEGFLTDAIFEDDGIKKAHIEKDFIAFCSSTPDNVSWRHPVRGSLFIESLIKHMKEYAWSCDLEDIFRKVRFSFEQPDSRLQMPTTERVTLTKRFYLFPGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5EG05-1", "uniprot_id": "CAR16_HUMAN", "id": "Q5EG05-1", "name": "Caspase recruitment domain-containing protein 16", "aln": "MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAETLGL----SAALQAVQDNP--AMPTCSS--------------PEGRIKLCFLEDAQRIWKQKLQRCH--------------VQNTIIKWSERYTSGSF---EMQWLFLRTNFIERFWRNILLLPL------------HKGSLYPRIPGLGKELQTGTHKLS------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******: *** **:*:. ***********:.********:.:* * ***:*:* * * * **.:*.*: *****:**.**** * * ** * ::. . * .*. *.* :*:* ** **::**:: .. : : ** :: .* ..... **: *: .: :. .*: * : ** * . : :.: ** * :: ", "identical_positions": 87, "similar_positions": 58, "identity": "21.64%" }, { "cls_id": "homologset.agr.HGNC:33702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R719-1", "uniprot_id": "M0R719_RAT", "id": "M0R719-1", "name": "MICOS complex subunit MIC13", "aln": "MVARVWSLMRFLIKGSVAGGAVYLVYDQELLGPSDKSEAVLRKAEEVVPPAMYQFSQYVCQQTGLEMSQLPAPPKINFPNFRDSWNSGIISVMAALSVAPSKAREYSREGWEYVKEHTK-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R404-1", "uniprot_id": "MIC13_MOUSE", "id": "Q8R404-1", "name": "MICOS complex subunit MIC13", "aln": "MVARVWSLMRFLIKGSVAGGAVYLVYDQELLGPSDKSEAALRKAEEVVPPAMYQFSQYVCQQTGLEMPQLPTPPKIKFPNFRDSWNSGIISVMSALSVAPSKAREYSKEGWEYLKEHSK-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XKP0-1", "uniprot_id": "MIC13_HUMAN", "id": "Q5XKP0-1", "name": "MICOS complex subunit MIC13", "aln": "MVARVWSLMRFLIKGSVAGGAVYLVYDQELLGPSDKSQAALQKAGEVVPPAMYQFSQYVCQQTGLQIPQLPAPPKIYFP-IRDSWNAGIMTVMSALSVAPSKAREYSKEGWEYVKARTK-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUK1-1", "uniprot_id": "MIC13_DANRE", "id": "Q1LUK1-1", "name": "MICOS complex subunit MIC13", "aln": "MAAKIFPVVKFATKVTIAGGALYVAYDSGLLGGSNEGSVALARAKSAIPPAVDEWMKYFG-------FELPATPKIEFS-PLDAWNSGVQKSIHALSVAPSTVGDYTKQGLQYVKDLSK-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVH3-1", "uniprot_id": "MIC13_DROME", "id": "Q9VVH3-1", "name": "MICOS complex subunit MIC13 homolog QIL1", "aln": "------MVLGFLVRGGLVAATVYYTQKVGIWGDSDQTDKLYNDIKSELRPHVQKLEKQLP----FEVPQLPKTGEMRFL-AKHYYNEGVKNTFRFIHMLPCYAGRGLKKVKDTFQDFAQSP--------------------AIAGGAESSPPK-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2T5-1", "uniprot_id": "Q9W2T5_DROME", "id": "Q9W2T5-1", "name": "MICOS complex subunit MIC13", "aln": "------MFTTLMYRTAAVSMTVYITNRVGVWGKTEETDHLLDQITNGLQPVFGLLRRTLK---------LDESDLSVGELSRKYYNEGVKGTFRIIRNIPNYSEELADGAKVTCLDLVEKAKELRHKEYSKWWNTSTNKEQLIIDSPDSAAGDGSFEDLVPFEKPKTVDNFAGEEGNGALEQRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : .. ::* . : * ::: . . : * . : . * . . :* *: : : * : ", "identical_positions": 7, "similar_positions": 25, "identity": "3.8%" }, { "cls_id": "homologset.agr.HGNC:33703", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D9N5-1", "uniprot_id": "CIB4_MOUSE", "id": "Q9D9N5-1", "name": "Calcium and integrin-binding family member 4", "aln": "MGQCLRYQMQWEDLEEYQALTFLTRNEILCIHDTFLKLCPSGKHYKEATLTMDQVSSLPALRVNPFRDRICRVFSHDNVFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFNENGFIDEEDLEEIVLRLLKSDDASEDLLMDVMHHVLSESDLDNDSMLSFSEFEHAMAKSPDFMNSFRIHFWGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZX64-1", "uniprot_id": "D3ZX64_RAT", "id": "D3ZX64-1", "name": "", "aln": "MGQCLRYQMQWEDLEEYQALTFLTRNEILCIHDTFLKLCPPGKHYKEATLTMDQVSSLPALRVNPFRDRICRVFSHDDVFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFNENGFIDEEDLQKIVLRLLKSDDVSEDLLQDVTHHVLSESDLDNDNMLSFSEFEHAMAKSPDFMNSFRIHFWGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0PJX0-1", "uniprot_id": "CIB4_HUMAN", "id": "A0PJX0-1", "name": "Calcium and integrin-binding family member 4", "aln": "MGQCLRYQMHWEDLEEYQALTFLTRNEILCIHDTFLKLCPPGKYYKEATLTMDQVSSLPALRVNPFRDRICRVFSHKGMFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFNENGFIDEEDLQRIILRLLNSDDMSEDLLMDLTNHVLSESDLDNDNMLSFSEFEHAMAKSPDFMNSFRIHFWGC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:******************************.**:********************************..:*******************************************:.*:****:*** ***** *: :***********.****************************", "identical_positions": 169, "similar_positions": 13, "identity": "91.35%" }, { "cls_id": "homologset.agr.HGNC:33704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHB8-1", "uniprot_id": "D3ZHB8_RAT", "id": "D3ZHB8-1", "name": "Transmembrane protein 198", "aln": "-MPGTMETLRFQLLPPEPD-DTFWGAPCQQPLE------RRYQALPALVCIMCCLFGVVYCFFGYRCFKAVLFLTGLLFGSVVIFLLCYRERVLETQLSAGASAGIALGIGLLCGLVAMLVRSVGLFLVGLLLGLLLAAAALLGSAPYYQ--PGSVWGPLGLLLGGGLLCALLTLRWPRPLTTLATAVTGAALIATAADYFAELLLLGRYVVERLRAAPVPPLCWRSWALLALWPLLSLMGVLVQWRVTTERDSHTEVVISRQRRRVQLMRIRQQEERKE--KRRKKRPPRAPPRGPRA---------------PPRPGPPDPAYRRRPVPIKRFNGDVLSPSYIQSFRD---------------RQTG------SSLSSFMASPTDTDYEYGSRGPLTACSGPPVRV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG75-1", "uniprot_id": "TM198_MOUSE", "id": "Q8BG75-1", "name": "Transmembrane protein 198", "aln": "-MPGTMETLRFQLLPPEPD-DTFWGAPCEQPLE------RRYQALPALVCIMCCLFGVVYCFFGYRCFKAVLFLTGLLFGSVVIFLLCYRERVLETQLSAGASAGIALGIGLLCGLVAMLVRSVGLFLVGLLLGLLLAAAALLGSAPYYQ--PGSVWGPLGLLLGGGLLCALLTLRWPRPLTTLATAVTGAALIATAADYFAELLLLGRYVVERLRAAPVPPLCWRSWALLALWPLLSLMGVLVQWRVTTERDSHTEVVISRQRRRVQLMRIRQQEERKE--KRRKKRPPRAPPRGPRA---------------PPRPGPPDPAYRRRPVPIKRFNGDVLSPSYIQSFRD---------------RQTG------SSLSSFMASPTDTDYEYGSRGPLTACSGPPVRV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66K66-1", "uniprot_id": "TM198_HUMAN", "id": "Q66K66-1", "name": "Transmembrane protein 198", "aln": "-MPGTVATLRFQLLPPEPD-DAFWGAPCEQPLE------RRYQALPALVCIMCCLFGVVYCFFGYRCFKAVLFLTGLLFGSVVIFLLCYRERVLETQLSAGASAGIALGIGLLCGLVAMLVRSVGLFLVGLLLGLLLAAAALLGSAPYYQ--PGSVWGPLGLLLGGGLLCALLTLRWPRPLTTLATAVTGAALIATAADYFAELLLLGRYVVERLRAAPVPPLCWRSWALLALWPLLSLMGVLVQWRVTAEGDSHTEVVISRQRRRVQLMRIRQQEDRKE--KRRKKRPPRAPLRGPRA---------------PPRPGPPDPAYRRRPVPIKRFNGDVLSPSYIQSFRD---------------RQTG------SSLSSFMASPTDADYEYGSRGPLTACSGPPVRV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q498W5-1", "uniprot_id": "TM198_DANRE", "id": "Q498W5-1", "name": "Transmembrane protein 198", "aln": "-MTSTLQTLAFKLAPPSREAGSGQLEPCSDVQG------RRYEVVPSVVCSMCCLFGIIYCFFGYRCFKAVLFLTGLMFGSVIIFLLCYKERVLDTQLSVEASVGIGLGIGTLCGLVTMLVRSVGLFMVGLLLGLLVGIGTLIGMEELSSNPPRSVWVPLGVLLGLGMLFAVLTLQWQRCFTTLSTAVFGAAVIVVATDYFVELFALVRYIYERVKTGPREPVCWTTWVVLGAWPALALLGVLVQWRVTAEGYSHTKVMISRQQRRVQLMRIRQKEERRESSRKKKRK------QPQSAQHTH-----------AAKALHPEPAYRRKPNPIRRFDGDVLSPSYIQSFRD---------------RQVDGRAYPVGGLMPSGHTSVDMDYDCGSTVPLTAGVGPHVRV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RBN9-1", "uniprot_id": "F1RBN9_DANRE", "id": "F1RBN9-1", "name": "Transmembrane protein 198", "aln": "-MTSPAQFLAFKLSLPSNDGSPERLFSCDEDIE------RRYEVVPSVVCSMCCLFGIIYCFFGYRCFKAVMFLTGLMFGSIIIFMLCYKERVMDTQLSVEASVGIGLGIGTLCGLVTMLVRSVGLFMVGLLLGLLVALASLVVLEEFYH--PRTVWLPLGVLLGSGMLFAVLTLQWQRCFTTISTAVFGSAVVTVTVDYFVELFALTRYIYERVKVDPPRQVCWFTWVVMGVWPVLALLGVLIQWKVTAEGYSHTEVFINHQQRRVQLMRIRQKEERRECRKKKKKKPQKQPPQQQQQKYHHPPQTNPHPPNPPPKVQHPEPTHRRKPNTIRRFDGDVLSPSYIQNFRD---------------RRADRRGYSHGRLIG-GSHVVDLDYDYGSQVPLTAHTGPVVRG-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K5P9-1", "uniprot_id": "A0A4D6K5P9_DROME", "id": "A0A4D6K5P9-1", "name": "Transmembrane protein 198", "aln": "MRVAADMVYDYGSEDSMSTTHLDWPFLIKGILEGQTCTPTAPEPLAAILWAIFAVFGIVYALLGYRCLRAVGFLSGLLVGANGIFIL---QDFQITFLGKPADSALAIVAGLLGAVLGSTYPVASVLISAFAGALLSGAAMAVCVATFPDN-EFGYREIYVAVVGGAVICSVLTLCCVKYVTILTSSIVGTAMILSAIDFFTHGLETINWIIG-MRPHPSPPPCYG-GLLIAAWPVTIVLSIMVQCFITAWRVDHRKRVYMRHHNHPGHAHGAHLPHSQQQAGPNHGIAPVRRSQSRTR---------------ETREEARQRKFR-YLYQVRTARGDIISQNFVSALQKRIQLSGTETPSERSIKSSSNERNTFRSDRTHFTTIHDPDSELCDKIEIVRDIGXQTSNSYMXLYP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . . : :.::: : .:**::*.::****::** **:**:.*: **:* : . * *. *. .:.: * * .:: ..::: .: .** . . : ::* .:: ::*** : .* ::::: *:*:: : *:*.. : .:: :: * *: ::. ** ::.:::* :*: .* : . :::.: : : . :: .: : .: : .* :: **::* .::. ::. : . * * : . :. * . ", "identical_positions": 47, "similar_positions": 125, "identity": "11.33%" }, { "cls_id": "homologset.agr.HGNC:33705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R975-1", "uniprot_id": "M0R975_RAT", "id": "M0R975-1", "name": "", "aln": "MSRSSPFRVGSKIPTMGYLCLPLFQLALSNLSCEDNEMCVNYDEQYPDGWSIWLLLLTVVVV-LLCGVVLFCLQCWLKSCGTDRPRRTMAVFAVGDLDPVYGAEMAGSPTAGICLPTQNTELC--PAPSLGALGPPPPYEEILKTN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P86045-1", "uniprot_id": "TM207_MOUSE", "id": "P86045-1", "name": "Transmembrane protein 207", "aln": "MSTSSPFRVASKIVTAGCLCLPLFQRVLSDLSCEENEMCVNYDERYPDGWYIWFFLLIFLVV-LLCGVVLFCLQCWLKRCGINPPRRTMAVFAVGDLDPVYGAEMAGSPTSGICHPTQNTELC--SAPCFGALGPPPPYEEILKAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWW9-1", "uniprot_id": "TM207_HUMAN", "id": "Q6UWW9-1", "name": "Transmembrane protein 207", "aln": "MSRSRLFSVTSAISTIGILCLPLFQLVLSDLPCEEDEMCVNYNDQHPNGWYIWILLLLVLVAALLCGAVVLCLQCWLRRPRIDSHRRTMAVFAVGDLDSIYGTEAAVSPTVGIHLQTQTPDLYPVPAPCFGPLGSPPPYEEIVKTT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * * * * * * * ******* .**:*.**::******::::*:** **::** .:*. ****.*::******: : *************.:**:* * *** ** **..:* .**.:*.**.*******:*:.", "identical_positions": 84, "similar_positions": 34, "identity": "57.53%" }, { "cls_id": "homologset.agr.HGNC:33706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LX90-1", "uniprot_id": "F1LX90_RAT", "id": "F1LX90-1", "name": "", "aln": "IRGCMHSTRDHTNHSRGEPSPSEAPAVISAHSKMPKSVSISKQLASIKALKRGSDLEKAMATIALVFRNASDPDGKLGKATAKNLLQTQFRNFTEREETKPKSRDLLSELDEHTEKKLDFEDFVILLLSLAIMSDLLQNIWSENTMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C9X1-1", "uniprot_id": "SNTAN_MOUSE", "id": "Q8C9X1-1", "name": "Sentan", "aln": "MGGCMHSTWDHALHSRGEPRPSEAPASISAPSKMPKSVSISKQLASIKALKKGSDLEKAIATIALVFRNASDPDGKLGKATAKKLLQTQFKKFTEREETKPKYQDILSELDEHTENKLDFEDFVILLLSLAIMSDLLRNMWNENTMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMZ2-1", "uniprot_id": "SNTAN_HUMAN", "id": "A6NMZ2-1", "name": "Sentan", "aln": "MGGCMHSTQDKSLHLEGDPNPSAAPTSTCAPRKMPKRISISKQLASVKALRKCSDLEKAIATTALIFRNSSDSDGKLEKAIAKDLLQTQFRNFAEGQETKPKYREILSELDEHTENKLDFEDFMILLLSITVMSDLLQNIRNVKIMK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": ": ****** *:: * .*:* ** **: .* **** :********:***:: ******:** **:***:**.**** ** **.******::*:* :***** :::*********:*******:*****:::*****:*: . : **", "identical_positions": 95, "similar_positions": 32, "identity": "64.63%" }, { "cls_id": "homologset.agr.HGNC:33708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H45-1", "uniprot_id": "TTC36_RAT", "id": "Q66H45-1", "name": "Tetratricopeptide repeat protein 36", "aln": "------MGTPNDQAVLQAILNPNTPFGDVVGLDL-EETE--EGDEDGVFPQAQLEQSKALELQGVRAAEAGDLHTALERFGKAISLLPERASAYNNRAQARRLQGDVAGALEDLERAVTLSGGR-GRAARQSFVQRGLLARFQGRDDDARRDFEQAARLGSSFARRQLVLLNPYAALCNRMLADMMGQLSAPSNGR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBW8-1", "uniprot_id": "TTC36_MOUSE", "id": "Q8VBW8-1", "name": "Tetratricopeptide repeat protein 36", "aln": "------MGTPNDQAVLQAIFNPDTPFGDVVGLDL-EEAE--EGDEDGVFPQAQLEHSKALELQGVRAAEAGDLHTALEKFGQAISLLPDRASAYNNRAQARRLQGDVAGALEDLERAVTLSGGR-GRAARQSFVQSGLLARFQGRDDDARRDFEKAARLGSPFARRQLVLLNPYAALCNRMLADMMGQLRAPSNGR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NLP5-1", "uniprot_id": "TTC36_HUMAN", "id": "A6NLP5-1", "name": "Tetratricopeptide repeat protein 36", "aln": "------MGTPNDQAVLQAIFNPDTPFGDIVGLDLGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGR-GRAARQSFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAALCNRMLADMMGQLRRPRDSR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E7I5-1", "uniprot_id": "TTC36_DANRE", "id": "A8E7I5-1", "name": "Tetratricopeptide repeat protein 36", "aln": "------MASAHDRAVLQAIFNPTSPIGDVPGLNQ--EEE--LMDDDSAFDPELVKQVKDLELQGVSSAESGDLPAALQHFNQAISVLPQRASAYNNRAQTKRLLGDTKGAVEDLEHAISLSNGK-GRSACQALVQRGLLLRLSGHDEEARLDFERAAALGSEFARQQAVILNPYAALCNRMLSEVISKLRNPEVSEMQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU70-1", "uniprot_id": "TTC36_DROME", "id": "Q9VU70-1", "name": "Tetratricopeptide repeat protein 36 homolog", "aln": "MPQANLTLSPHDQQVLDSIFNP-LELSSLQTNNLIPAES---DLKDEEPDTQAIKASRELELKAIALSESGELDGALELFQQSLN-LAQRASVLNNRAQTLRLAKRDEEALDDLNKALELANDQQTRTKCHAHCQRGVLYRKLDNLEAARADFEAAAQLGSKFAREQLVEINPYAALCNQMLRQAFDQLK--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:*: **::*:** :..: : . .* :: : ***:.: :*:*:* **: * ::: *.:***. *****: ** *::**::*: *:..: *: :: * *:* * .. : ** *** ** *** ***.* * :********:** : :.:* ", "identical_positions": 63, "similar_positions": 54, "identity": "31.82%" }, { "cls_id": "homologset.agr.HGNC:33709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R8J6-1", "uniprot_id": "M0R8J6_RAT", "id": "M0R8J6-1", "name": "", "aln": "MTSTNKGGE-AKKQGVSRKQLLEELNEKRESYCLVERSNRVSLLRVQKRHFSQAYQSLSSMNVKESVPESSRTSWIERD--LFVHKEKRHFVPKNHAIFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CVW4-1", "uniprot_id": "SPT45_MOUSE", "id": "Q9CVW4-1", "name": "Spermatogenesis-associated protein 45", "aln": "MTSMNKGNE-EKTQGANRKQLLEELNEKRESYCLVERSNEVNLLRVQKRHFSKAYQTLACMHIKESVPESTRTSWVKHD--LSVHKEKRHFLPKNNAIFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q537H7-1", "uniprot_id": "SPT45_HUMAN", "id": "Q537H7-1", "name": "Spermatogenesis-associated protein 45", "aln": "MASINRTIEIMKKHGVSKQHLLEEINKKRESNCLVERSNQVSLLRVQKRHFPDAYQSFTDTTTKEPVPNSGRSSWIKLS--LLAHMERKHFPPKNNAIFG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGS7-1", "uniprot_id": "SPT45_DANRE", "id": "Q5RGS7-1", "name": "Spermatogenesis-associated protein 45", "aln": "---------------MSKQERLYELNMHRETWCRVETTSKYWNLP-ERKHFRCHLQNTCDISALQTASPEQRSAWMSSGGQNTAHPERRHFEDSYRAHLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::. * *:* :**: * ** :.. * :::** *. :... . *::*:. . .* *::** . .* : ", "identical_positions": 19, "similar_positions": 30, "identity": "19.0%" }, { "cls_id": "homologset.agr.HGNC:33710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3A2-1", "uniprot_id": "CDPF1_MOUSE", "id": "Q8R3A2-1", "name": "Cysteine-rich DPF motif domain-containing protein 1", "aln": "------------------------------MASETEPRPLGTFECQLCALSAPYSYVGQKPPDTQAVVLLEESYIMKDPFSS-------DKARFLVLGSRCSVCSRLVCVGPDCSLFYSKRVCLPCVQENMSAFPQEIQQDVEKRKSTSKKHSNRP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AB90-1", "uniprot_id": "D4AB90_RAT", "id": "D4AB90-1", "name": "Cysteine-rich DPF motif domain-containing protein 1", "aln": "------------------------------MASEAEPHPLGMFKCQLCALTAPYSYVGQKPPDTQAVVLLEESYIMKDPFSS-------DKARFLILGSRCSVCSRLVCVDPECSLFYSKRVCLPCVQKNISAFPQEIQQDVEKRKGASKKHSNRP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVV7-1", "uniprot_id": "CDPF1_HUMAN", "id": "Q6NVV7-1", "name": "Cysteine-rich DPF motif domain-containing protein 1", "aln": "------------------------------MASHVECRPLGVFECELCTLTAPYSYVGQKPPNTQSMVLLEESYVMKDPFTS-------DKDRFLVLGSCCSLCSRLVCVGPECSLFYSKRFCLPCVRENINAFPQEIRQDLEKRKAPSKRTPSQPGSRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGZ1-1", "uniprot_id": "CDPF1_DANRE", "id": "Q5RGZ1-1", "name": "Cysteine-rich DPF motif domain-containing protein 1", "aln": "-------------------------------MDLTEGSALGVFSCQLCEVSSPYSFYGQKPPNTRAIVLLEECFGIKDPFSP-------EREKFLILGSKCSLCSKTVCVG------------------------------TVRRSCDSQSEAKL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHN3-1", "uniprot_id": "CDPF1_DROME", "id": "Q9VHN3-1", "name": "Cysteine-rich DPF motif domain-containing protein 1", "aln": "MDPDDDLVLENEAEEIERLQLPEELKKPIDPEEEDERVARIEFNCSGCEMHEMVHYFGRKPPFALGVIYPEDNYVMRDPFQPPPPRWQSKPEYYIAMGTKCSICSKTVCKDPGCSFYYTASFCLPCGKEELKNWPPEAQARIRKQMSVSQGRQT------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . *.*. * : : *:*** : .:: *: : ::*** . . :: :*: **:**: ** . :: *: . ", "identical_positions": 20, "similar_positions": 28, "identity": "12.5%" }, { "cls_id": "homologset.agr.HGNC:33711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BL86-1", "uniprot_id": "MBLC2_MOUSE", "id": "Q8BL86-1", "name": "Acyl-coenzyme A thioesterase MBLAC2", "aln": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDCGSKEDAGRR-PLLAVATHVHFDHSGGLYQFDQVAVHRAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKVLFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNPRTSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A249-1", "uniprot_id": "D4A249_RAT", "id": "D4A249-1", "name": "Acyl-coenzyme A thioesterase MBLAC2", "aln": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDCGAKEDAGRR-PLLAVATHVHFDHSGGLYQFDQVAVHRAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKVLFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNPRTSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68D91-1", "uniprot_id": "MBLC2_HUMAN", "id": "Q68D91-1", "name": "Acyl-coenzyme A thioesterase MBLAC2", "aln": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDREAKEDAARR-PLLAVATHVHFDHSGGLYQFDRVAVHHAEAEALARGDNFETVTWLSDSEVVRTPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKILFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNSRTSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0T6-1", "uniprot_id": "B0R0T6_DANRE", "id": "B0R0T6-1", "name": "", "aln": "MAATDWYAHKSLENGVFWIQERFYESGNRANIWLIRGSHQDVVIDTGLGLRSLPEYIQEKSLLGD-----DAKRKNPLLAIGTHVHFDHSGGLHQFQQVGVHKAEVDALANGDNFETVTWLSDREIVEVPSPGWRARQYRVKAVTPTHILQEGDVINLGDRQLSVLHMPGHSRGSICLHDKESKMLFSGDVVYDGSMIDWLPYSRISDYIHSCERLVEMVDKEEIDQVMPGHYNTFGGKRLHRLASNYIASAGTCHRASTSVVKSIASLALRASNSRSAC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* :******* :*:******************:***.*****************: ...** * ** *: ****:.***********:**::*.**:**.:***.************ *:*..*********:**:** ** ***:***********:*:***************: *:***********:************: :****:*:**: :::*:***:****.:**.*******:.** **:.** .::*:******.:*.*:: ", "identical_positions": 201, "similar_positions": 58, "identity": "71.79%" }, { "cls_id": "homologset.agr.HGNC:33713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V2K1-1", "uniprot_id": "CX065_MOUSE", "id": "Q3V2K1-1", "name": "Uncharacterized protein CXorf65 homolog", "aln": "MFIIIKHGDNQEFLVNSNCSVLLLLHYIRKKMKLRKTDTIDLCDESGTMKLLFLSKT-PGDSASKFLTARNTYYVCKVERGAPGTRIENSYKAIVPMLKNPEPELVDSLRTQCDFLERSRIKMLRTLEAKRLAAMESSVNLPARSPKGGGAQQTTSTSSQLKSKGGRSDEDGPPSTRRPFYKTRADFLKRHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NEN9-1", "uniprot_id": "CX065_HUMAN", "id": "A6NEN9-1", "name": "Uncharacterized protein CXorf65", "aln": "MFIFIKHGDNQQFLVNTNCAVVVLLYYIRSKVKLPKTNTIDLCEQTGKMKMLFLMKPNHAEYASKYLTARSTYYVCKVERGPPGTRLENAYRAFVPLLKNPEPWLLVALRIQCDALERRRIQMLKMKEAKKVVIIEPPASVPSKQSGRSDKKKSTRKSPTFRNRPDFRKNKG-----RQLNKT----TKQKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*******:****:**:*::**:***.*:** **:*****:::*.**:*** *. .: ***:****.**********.****:**:*:*:**:****** *: :** *** *** **:**: ***::. :*....:*::.. .. :::* .*. ::.: . .:.* * : ** *:::", "identical_positions": 97, "similar_positions": 62, "identity": "50.52%" }, { "cls_id": "homologset.agr.HGNC:33714", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91V79-1", "uniprot_id": "FITM1_MOUSE", "id": "Q91V79-1", "name": "Fat storage-inducing transmembrane protein 1", "aln": "--------------------------MERGPTVGAGLGAGTRVRALLG-----CLVKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVN------SRTIFASHGNFFNIKFVNSAWGWTCTFLG-------GFVLLVVFLATR--RVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLP-----------QG---LLLHELPDRKSCLAAGHQWRG-YTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAP------------------------------------LRLVFLLNVLLLGLWNF------LLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQP---WSPGIPGHGLFPRSRSM-----RKHN---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZIQ3-1", "uniprot_id": "D3ZIQ3_RAT", "id": "D3ZIQ3-1", "name": "Fat storage-inducing transmembrane protein 1", "aln": "--------------------------MERGPMVGAGPGAGTRVRALLG-----CLVKVVLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVN------SRTIFASHGNFFNIKFVNSAWGWTCTFLG-------GFVLLVVFLATR--RVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLP-----------QG---LLLHELPDRKSCLAAGHQWRG-YTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAP------------------------------------LRLVFLLNVLLLGLWNF------LLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQP---WSPGIPGHGLFPRSRSI-----RKHN---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5D6W6-1", "uniprot_id": "FITM1_HUMAN", "id": "A5D6W6-1", "name": "Fat storage-inducing transmembrane protein 1", "aln": "--------------------------MERGPVVGAGLGAGARIQALLG-----CLLKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVN------PRTIFASHGNFFNIKFVNSAWGWTCTFLG-------GFVLLVVFLATR--RVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLP-----------QG---LLLHELPDRRSCLAAGHQWRG-YTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAP------------------------------------LRLVFLLNVLLLGLWNF------LLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQP---WSPGSPGHGLFPRPHSS-----RKHN---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5CZN0-1", "uniprot_id": "FITM1_DANRE", "id": "Q5CZN0-1", "name": "Fat storage-inducing transmembrane protein 1", "aln": "-----------------------------------------------------------MFLNSILVVI-TDLAAGLLGNTSFRRHFHLLLSALLLFGPLLSLWVS------HYSVFAKRTHFLYRVFLRSGWGWTCIFVG-------SFVFVLSFSVRR--SLTLSLRHLSRLAVAGGLWLGFRKLLCLLENATGSCYEPLSAALEMTSGTNGEGQPLLLLREAETKETCVRSGMLWRG-YEVSEDALLLCLCCLLLAEETAVFGPYLNLGGPSEAP------------------------------------LRILFLFCVLLLSLWVF------LLLCLLAYFPEFPTQLLGGALGCLSWRALYQGWYRLRPSWYCPGRPGVGLLSTQSKQDELLETQTNAKEID----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRJ2-1", "uniprot_id": "FITM2_DROME", "id": "Q9VRJ2-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "-----------------MATKRRPLRPNLGGTAGSPSSSGSNMNFRPGGPDITRSEARGTRPTAAPTSIREILVMGVIHLCKKTIFFNTDLKVALYLGSLFVISVIGDFVPFPKTYFARSDNLFNQYFVKIGWGWTLLFVV-------PFLVLSAYTITCGDHKRMLRHHFPRIVIATFFWFFWTKLFNVVENSYGRCTTKGY----------------------ATKSSCLKAGHLWKG-FDISGHAFILIHSSLVLIEEARPIIRWETIKEHIRNERHNRSTAENSGTNPLRTLNEEQMRSLQFLYKRLTPIIRTLFIGMAALQLLWDI------MLVGTMLYYHRMIEKVISGIIAILTWYFTYRFWYPTPG--LLPEAPGNGSFSYQREIPTFPFKRPSHLSTGAATTSSGSNSSRTNLNGKAATTGVPRDQQIPTFMGMPLFTSPKAASAAANLLMSDQQKRERDREQQTLES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53012-1", "uniprot_id": "SCS3_YEAST", "id": "P53012-1", "name": "Acyl-coenzyme A diphosphatase SCS3", "aln": "MSSKWFNAIHLLVCPLTVLVGYLMNAYGYGAALQATLNKDGLVNAMLVKKGWFWTSLVGWWCIIRYRAVPGATGRDRRHIVQSFKRYAILTVWWYVFTQGIWFGVG----PIMDLVFVYTGGHCHYDVFDDAGHVNEDFQGSVTRTNRALALIHNVLTLHGHHQEHRQQQLWDRSIGSIQGALQATQPKTPKNVTASAAAAIN--------TFIHDQMHRWQGPLTTSAQCRRFGGHWAGGHDPSGHVFLATLMCMFLLGELRVFGRRALAHLYAQKWQ-----------------------------------LVRLVTRLFDTGPLWTWRRCGGGSMTCGARLWRAIVEPPVTCAAALLRLTRCIACDHPVIILLTLLVTWLWQLLLTAVASRFHTVREHMSGLLAAYIVTGLVYARDAAALRPV---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : * *. .. . . * : .: ::: :. :: . . * * * * . * ..:: .:.: * : : :. ** : : : . : : : . ", "identical_positions": 11, "similar_positions": 43, "identity": "2.3%" }, { "cls_id": "homologset.agr.HGNC:33715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1L0-1", "uniprot_id": "D4A1L0_RAT", "id": "D4A1L0-1", "name": "", "aln": "----------------------------MDTRDDVTLAKVVAPVAVYCGSVPRTSVGLRAPPPGSIDSS--------EASPQPVSSVLPSSEKPSQLLSGHEDQSSLTLDAPLKGWQARNGYPRNLR------------ALPLGPHPLAVIPSLESEASSVAR----------DTIQIKDKLKKRRLSEGMAASSQVSLDPVGGPKG-------VPLRSTIPRTASQRLLR--VPRPMPPIQSIPTTPEANSAKEKDLDPPGGR-----PGAGAQEVQISRQYLHCADEKMHKS------------------------------------------LGGIVIPPIPKARMPTGTSSCRPGSRSSPLCPGQDGLMGTRAPPTRLTCE---------------NGPLEKTPKSLAPKPLVPAVKAKSAEAPPTSLASSQSTFTLTAFS-SHAKETRSLTNEEDQRESSTKVQVTISKSAQEKMRLKQLKEMELLRRAKEPERERELASQGLGTWRTSAKEGLLPLR----GSGTLSEPTGMSSPRRNNIGVLQRKRANRASLPNIPVS----------------------KQEPGFARHASANSLP------AMLTLGSPEWEEEEEEEMDLQALREFRPFS--------NPELGLTEALQCLSSNDWQMKEKGLVNIQRLAACHSEVLGTRLHDVSLAVTAEVTNLRSKVSRLAISTLG----------------DLFRALKKSMDQEAEEIVRCLLQKMGN----------------TSEFIQRAANRALGAMVENVTPARALVALTSAGVY---HRNPLVRKCTAKHLSAVLEQIGAEKLLSGSRDNTD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLVHNLVRLAQDSNQDTRFYGRKMVNILMANAKFDAFLKQSLPSHDLRKVMAAIKQRGIQDNHELPSAKGRK-----------------------VLKSLVVCENGLPSQEGLGSNGPRLVGLRSSMRGGVEMAEQLR--------------------------------------ELTRLLEAKEFQARMEGVGKLLEYCKTKPEHVAANLVQVFDAFTPRLHDSNKKVN-------------------------QWALESLAQMLPILRESIHPMLLS-----LIIVAADNLNSKNSGISTAASTVLDAMMDSLDHLCLLQAFAG------------------RVRFLTGPAVLDVTDR-LSALVASVYPRKPQAVERHILPVLWYFLNKMTG-------------------NGVLPGRGGNVRTAVCRLARSLQEQMG-------SRLQDFAANQPQQALKTLQGLLVSESLGDNNKVTSGGMAPDIQMTGAICPQQLD-------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TYG6-1", "uniprot_id": "TGRM2_MOUSE", "id": "Q3TYG6-1", "name": "TOG array regulator of axonemal microtubules protein 2", "aln": "----------------------------MDTRDDVTLAKVPAPVAVYCGSVPRTSVGLRAPPPGGIDSSL---LAHDEASLQPVSSVLPSSEKPSQLSREHEDQSSLMLNAPLKGWQARNGYPRGLG------------VLPLGHHLGAAIPSLESEASSVAR----------DTIQIKDKLKKRRLSEGMAASSQASLDPVGGPRG-------VPLRSTIPRTTSQRLLR--VPRPMPPIQSIPTTPEANSAKEKDLDPPGGRQDLQDPGASAQEVQISRQYLHCADEKMHKS------------------------------------------LGGLVIPPIPKARMPTGTSSCRPGSLPSPLCPSQDVLMGPKAPHTRLTCE---------------NGPLEKTPKSPASKPLVPVVKAKSAEAPETSLASSQSTFTLTAFS-SHAKETRSLENEEDQKESSTKVQVTISKSAQEKMRLKQMKEMELLRRAKEPEWERELVSQGLGTRRTSAKEGLLPLR----GSGALSEPAGMSSPRRNNMGALQRKRANRASLPSIPVS----------------------KQEPGFARHASANSLP------AVLTLGSPEWEEEEEE-MDLRALRELRPFS--------NPELGLTDALQCLNSNDWQMKEKGLVNIQRLAACHSEVLGTRLHDVSLAVTAEVTNLRSKVSRLAISTLG----------------DLFRVLKKNMDQEAEEIVRCLLQKMGN----------------TSEFIQRAANRALGAMVENVTPARALVALTSAGVY---HRNPLVRKCTAKHLSAVLEQIGAEKLLSGSRDNTD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLVHNLVRLAQDSNQDTRFYGRKMVNILMANAKFDAFLKQSLPSHDLRKVMAAIKQRGIQDNHELQSAKGRK-----------------------VSKSLVVCENGLPSHEG------------------VETSEQLR--------------------------------------ELTRLLEAKEFQARMEGVGKLLEYCKAKPELVAANLVQVFDVFTPRLHDSNKKVN-------------------------QWALESLAQMLPILKESIHPMLLS-----LIIAAADNLNSKNSGISTAASTVLDAMMGSLDHLCLLQAFAG------------------RVRFLTGPAVLDITDR-LSVLVASVYPRKPQAVERHILPVLWYFLNKMSG-------------------NGVLPGRGGNVRTAVCRLARSLQEQMG-------SRLQDFAASQPQQVLKALQGLLASESLGANDKVIGGRMAPDIQMTGTTCPQQLD-------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUX3-1", "uniprot_id": "TGRM2_HUMAN", "id": "Q6ZUX3-1", "name": "TOG array regulator of axonemal microtubules protein 2", "aln": "----------------------------MGTRDDVPEAKVLVPVAVYCGSIPRTSAGPRVLPPGSINSS----LPHGEGSLQPEPRALLNNEEPSQLLRGLGQLGGLKLDTPSKGWQARNGHPRNLR------------ALSLGDQPLVLLPSPESEANSVAR----------DTIQIKDKLKKRRLSEGLAASSRASLDPGGGPQG-------VPLHSTIPRATSQRLLR--VPRPMPLIQSIPTTPEASGVKEKGLDLPGSIPGPHELRPGAQEAQISWQYLHCNDEKMQKS------------------------------------------LGAIVIPPIPKARTVAATPSRVPGSLPSPLPPGQGVLTGLRAPRTRLARG---------------SGPREKTPASLEPKPLASPIRDRPAAAKKPALPFSQSAPTLTAFSFDCAREACPPLKEEDQKEIGTKIQVTISKSAREKMQLKQMKEMELLRRLEEPRTGQELTSQCLGSQRAFMKEGLLPLR----GSGTLSVPTRLSGPCRNDVSIILRKWASRASLPSIPIS----------------------RQEPRFARHASANSLP------AVLTLGSPEWEE--EEEMDLRACKELRPFS--------NPELGLRDALQCLNSSDWQMKEKGLVSIQRLAACHSEVLTGKLHDVCLVVTGEVTNLRSKVSHLAISTLG----------------DLFQALKKNMDQEAEEIARCLLQKMAD----------------TNEFIQRAAGQSLRAMVENVTLARSLVVLTSAGVY---HRNPLIRKYAAEHLSAVLEQIGAEKLLSGTRDSTD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLVHNLVRLAQDSNQDTRFYGRKMVNILMANTKFDAFLKQSLPSYDLQKVMAAIKQQGIEDNDELPSAKGRK-----------------------VLRSLVVCENGLPIKEGLSCNGPRLVGLRSTLQGRGEMVEQLR--------------------------------------ELTRLLEAKDFRSRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPRLQDSNKKVN-------------------------QWALESFAKMIPLLRESLHPMLLS-----IIITVADNLNSKNSGIYAAAVAVLDAMVESLDNLCLLPALAG------------------RVRFLSGRAVLDVTDR-LAVLVASVYPRKPQAVERHVLPILWHFLNTATR-------------------NGTLPGPSGNIRGVVCRLSRSLQEHMG-------SRLLDFAASQPKHVLKTLQELLDSESLGGSRKATDRGVAPDSKTTGSSYPFQLD-------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPK5-1", "uniprot_id": "Q9VPK5_DROME", "id": "Q9VPK5-1", "name": "TOG domain-containing protein", "aln": "MFFRRVLDSARNHLPPKSTTESPAVHYYSEDSESVTYVSGAVDCEVKDSNNNQSAVGAGAPLPAIMKIQRRAEAPIGAVQLTPLWEHILRTRRLPETIFPSAMYAEFHERLQDPEWQVRQHALRVLVDVLVVMQDEADGHMEREQLIGLLVENLGHQAPTVRKGALDCLRVYLAETAIPETVMLGILDAGLTKQVPADSEHMGRLSCGVLLSVPALLQSIMHTAQRHRIVHSTVERVVAHMDQVVQQEITVKVLSKIRELLGVHEFEEIMGNVGRGDTLSRYYQLSQVYGVSGKSKTGGEVKAGAWRALPREQGWRNGNAVQNLDTTLQIQSNCLDMGKIIMETEIKINDDTVTMRILEADTETEESDSPTRIFSNEEDGTDLICHPLSSSGSTHQEPNIGAGIVKVISDSELDEPHIKAGSVSEPGTPSRGLKRVTFGGEIVKMRTPDSDAASSTNNSRSPTQTNQSITVSSSEDAAISDLVSSDEKSTLSRPVNDKRTTALVLEIPFDNTKPLPQDRSLCSQPHRHQSNAQSEPSSNSPRNRQENKARLSPSPSSPGFRSRSTSPTGSNNISPKVPHKQIEVLHNLQRDPSPRSQRRSEDMDGNGDGKALHATGNPSSSPTQPLISRTRSASTMSPVSPATPKSWEDLDIVNLKTLLELRSGDWRNRLMGIGQLELALSSSSNLALVQPYLDSLLRTLLSSERHFEVSDLKRELLVNLISRLPLDNLEERTPQILSGLCRQGNAGANRVCKALMQRLPAGTIVAKLTSPEFLHAKSSKFRDHALQMSIFALMTFPGTCFDISLLTTQAVYSLLNRKRRVRQAALEVLAVLADISSIKEVLTIVSETTDGVELGPMVLEATSVRLSRLQLPIVTPDSGVLFVFNQTDPPGARRFGADVDWIHQGEGSASPNTIKRRRMRAASSQRNVLGGAEAKNKNDPFPSFRQVNESVHRHSFHSPPETLDMASPINDFSQRLSFGAKTNGGSQSFIERRFLAKACSDTSMDGRSTDSTTTTCSSGSATDSFIQLTSRTGGRLAGPNSRFPTMNQHADFVNNFMRSMQRGSKSHSVERPNYPKVSYSIPKSQQMIRKKFQHKDSFTKLGDEPPGQSIENNKFNESQRRKSGISTDHMESLDSKCADVIKSVDTETEVNGMTNGSPISASSTSYSQKSTASAKSSISQNEMGKRPFSSTGLWNDCKVEVLNREHNPNEAFGELVVDAIKVQTESEPTAHEELLKLNGSLNSLHSKTESIKTQLEETTPQLSRAQSVKSLLIEEDIESSNSFVVVEEVENELESSPAKGEEEVPLQEELATPVKATKLENHTFGPKLVPTHDEIVIHSRSVSLDSLYGTRPASKQGSMDTSTSTAENTSQTGSQIGNTSVPAKAQHTPLKHKSKTSYFLRAQRRISPSKQPIKMSQAELFPQNMVRFDRPREALLKTFDQLDSSNWEVNVSGLKSMVRLIRYHAETLDNQMHMTCIQLTRSVRNLRSQVARASCQAAAELFSLKSTSLQQECDDLVCALLHRTADTNRFLRADANRALESMVDHAQPQKILNILATKGAQHQNALVRTTSAKLLFRLVERLGSDRIYAMGRESRDKFFVVGANLLLEGSLETRSYAKSLFRALSENHNYQRLLLEVIPPRTYRNVEKTLRSITR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*. .. . * .. :::.* . *. :. . . * : ... .: . : **.*: * * : : . :* :* : * :.: *. *:: . .. : * . *:* : : :*::: * * :. ::.: : . .* : * .: :* * . : . :* ::: . * . : * .. : . : . . * * * : . * :* . : .* :. : : : . :... : . .: *: *:.* . :.. :: * * :: . : . :.. :. :: * : *.: * *: * *:: .. ..: . . * :::* : ::.: *: : *.*. . :: : *.* : :: .:* * *.**: : *: .:: :. *:: : : .* * :: : :** * . * ::: * :. : *:.: :.*:*:: :.:* ::* :: *:: . : **: .** :*: :*: : : *:.: : . :::*: :.** :*:*::* * ..:. . : :: : .* : ::::.: * . :. :*.:: .:: ** . .: ** * . * :: * * * .:.. ::.: . * *:: * .:.:* :. .. : :.:. :. * * * : .: : ..:: * *:. :* : .*:* . :: :*: : :: . : * ** . :. :.: : *.::*:: .:* .:* * : : .* . : * *.*:.::. :.* .: :.. :: . * * .: . . . . .. * :: ", "identical_positions": 127, "similar_positions": 355, "identity": "7.67%" }, { "cls_id": "homologset.agr.HGNC:33716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNM5-1", "uniprot_id": "A0ABZ3NNM5_RAT", "id": "A0ABZ3NNM5-1", "name": "", "aln": "---------------MAASAG---------------GPGSWSENILTYFLRNR----QITAEDGAEILWYHAANHKCQMSDALKSAA--HMIEADVLLPSDGSEHG-QPIMAHPPETGSDNTLQEWLAEVTKSN-------KGIKLDFKSLAAARASMLFLDN----VKQHLQRPVWINADVLPGPN--GSSKVVDAKAFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGYTWPMVKEMDYICS-----ELTQPVTFPVRAALVRQSCSQLLWLLTKS---SRYSLTVWTGKDDIYPTEDLLYIRDCFNKTQVFYDILEPQN------------YEFKQAIGIR-HSLRI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YUE4-1", "uniprot_id": "F151B_MOUSE", "id": "D3YUE4-1", "name": "Protein FAM151B", "aln": "---------------MAACAG---------------GPGSWSENILKYFLRNN----QITAEDGAEILWSHAANHKSQMNEALKSAA--HMIEADVLLPSDGSEHG-QPIMAHPPETSSDNTLQEWLAEVVKSN-------KGIKLDFKSLAAVRASMLFLDN----MKQHLQRPVWINADILPGPN--GSSKVVDAKAFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGYSWSMVKEMDYICS-----ELTQPVTFPVRAALVRQSCPQLLWLLTKS---NRYSLTVWTGKDDIYSTEDLLYIRDYFNKTQVFYDISEPQN------------HEFKQAIGIRGHSLRI----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXP7-1", "uniprot_id": "F151B_HUMAN", "id": "Q6UXP7-1", "name": "Protein FAM151B", "aln": "---------------MAASAG---------------GPGSWSENILEYFLRNS----QITAEDGAEITWYHAANHKAQTNEALKSTA--HMIEADVLLPSDGSEHS-QPIMAHPPETNSDNTLQEWLTEVMKSN-------KGIKLDFKSLAVVEPSMMLLEN----VKRHLKRPVWINADILPGPN--GNSKVIDAKPFLDTVISFFPDVTFSLGWTTGWHPEKVNEGYSWTMVKEMEYICN-----ELSQPVTFPVRAALVRQSCSQLLWLLKKS---NRYSLTIWTGKNDNYSVEDLLYIRDHFDKKQVFYDILEPQN------------HEFKQAIGIKVNL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGP9-1", "uniprot_id": "A2BGP9_DANRE", "id": "A2BGP9-1", "name": "", "aln": "-----MGLVKHKLYRFIACAAIIASLIVFYLKLQSISKGSMSEQTLEYFLNKG----TIRRKDAADIEWYHAANSKSKLIEALRGSA--QMIEADVLLR--GADPE-EPIMAHPPAKDSDITLQDWLKEVVKSD-------KGIKLDFKSLAAVSQSMSLLEE----VRDQLKGPVWINADILPGPG--GTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCR-----PLKQPVTFPVRASLLPMSFPQFQWLLEQS---DRYSLTVWTGKDDALNVNDLMPYRKNLGKRRIYYDLLESQI------------KQFKALAGYD----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU9-1", "uniprot_id": "Q9VLU9_DROME", "id": "Q9VLU9-1", "name": "Menorin-like domain-containing protein", "aln": "MDSKITFLLTTLLFVLVAKINGSALNASNYQYQVVVEQTAPDDSQIEYIFLKQSDMMKVWGTNLTAITWAHAVNSQQLLDEVLTETSGIDFIEADIVLGKLNGDGEDMPIMAHPPANVSDLTLSEFLNQIINFNRDHEDQKKGVKLDFKSIEVFEGSLDILDVNIPNVSLPTTYPVWINADILSGPVEQNRTVPVDADRFFAGCMR-YKQAVLSIGWTTNWGADFRDGEYTQQQCDDMLETLSENNVLSTGQAITFPVRAGIAANSEEQLHRLVAAVNETNESTLTIWSSAGDYVDVDKLRKLIFSFGLDRVYLDVPEELASQLNLDNPGNGASTFKSLFGFSFMSLCFWALSSWMQRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : .:. : *:: : : : : * * **.* : :.* :: .:****::* ..: ******* . ** **.::* :: : : **:******: . *: :*: : *******:*.** . : :*.. *: : .:*:****.* : : *: .:* *.:******.: * *: *: .. :**:*:. .* .:.* :. ::: *: * ** * ", "identical_positions": 75, "similar_positions": 80, "identity": "20.89%" }, { "cls_id": "homologset.agr.HGNC:33717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJG1-1", "uniprot_id": "D3ZJG1_RAT", "id": "D3ZJG1-1", "name": "Protein-lysine methyltransferase METTL21C", "aln": "MDQHLHTAQQPLRLG----------------TPQEDVFAGPSVESDMIESSLHSIQKFVPTDYASYTQEHYHFAGKKIIIQESIENYGTVVWPGATALCQYLEDHTEELNLEDAKILEIGAGPGLVSIVSSLLG-------AQVTATDLPDVLGNLQYNISKNTLECTAHLPEVKELVWGEDLDQKFPKS-----SFYYDYVLASDVVYHHYFLDKLLATMVYLSQPG--TVVLWANKFRFSTDYEFLDKFKQAFDTTLLAEHSESSVKLFKGILKWD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLU2-1", "uniprot_id": "MT21C_MOUSE", "id": "Q8BLU2-1", "name": "Protein-lysine methyltransferase METTL21C", "aln": "MDQHLHIAQQPLLSG----------------TPQEDGFAGPSVEFDRIESSLRSIQKFVPTDYASYTQEHYQFAGKKIIIQESIENYGTVVWPGATALCQYLEDHTEELNLQDAKILEIGAGAGLVSIVSSLLG-------AQVTATDLPDVLGNLQYNILKNTLECTAHLPEVRELVWGEDLEQSFPKS-----TCCYDYVLASDVVYHHYFLDKLLATMVYLSQPG--TVVLWANKFRFSADYEFLGKFKQAFDTTLLAEYSESSVKLFKGILKWE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZV1-1", "uniprot_id": "MT21C_HUMAN", "id": "Q5VZV1-1", "name": "Protein-lysine methyltransferase METTL21C", "aln": "MDVCLSSAQQPGRRGEGLSSPGGWLEAEKKGAPQKDSTGGVLEESNKIEPSLHSLQKFVPTDYASYTQEHYRFAGKEIVIQESIESYGAVVWPGAMALCQYLEEHAEELNFQDAKILEIGAGPGLVSIVASILG-------AQVTATDLPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKS-----AFYYDYVLASDVVYHHYFLDKLLTTMVYLSQPG--TVLLWANKFRFSTDYEFLDKFKQVFDTTLLAEYPESSVKLFKGILKWD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53970-1", "uniprot_id": "EFM6_YEAST", "id": "P53970-1", "name": "Protein-lysine N-methyltransferase EFM6", "aln": "MESIFGGFGDLVVPR------------------PKEHLG---------QTDLSFGGKLLPALKICEDGGESGCGGKVWIAGELLCEY------ILEKSVDHLLSKTVNGTKQFKKVLELGSGTGLVGLCVGLLEKNTFHDGTKVYVTDIDKLIPLLKRNIELDEVQYEVLA---RELWWGEPLSADFSPQEGAMQANNVDLVLAADCVYLEEAFPLLEKTLLDLTHCINPPVILMAYKKRRKADKHFFNKIKRNFDVLEITDFSKFEHYLKERTHLFQLIRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : : :: . :..* *::*: . . .** : * : .* ::* .:: : . : *:**:*:*.***.: .:* ::* .**: .:: *: *: : :: . :** *** *. .*. . : * ***:* ** . : * *:: *:: .*:* * * * .:* .*:.*:*: **. :::..: . * : :: ", "identical_positions": 52, "similar_positions": 80, "identity": "18.44%" }, { "cls_id": "homologset.agr.HGNC:33718", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIM8-1", "uniprot_id": "D3ZIM8_RAT", "id": "D3ZIM8-1", "name": "", "aln": "MAYDHSDASCGATMACRTIEYTTETGEDQKVMAYCRYTQDWSMPTPG----VKGAREQAKKSAP--------VAGAGEKRKKGPWTTEPPKPGWALTQEKLAAMSSTVRRRHLLFSDLLDMV-EVGSMFPRESVELSYCMPDPRIWTQALELPSERQNRLLGILKAAEARGRIRALRLRYTRMRAEEISLLIQKQRCARAAIRLELFLPPQLKPTKIPDPLDRQERRRVETILEEEVDGNIFPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIG2-1", "uniprot_id": "LKAM1_MOUSE", "id": "Q8BIG2-1", "name": "Protein LKAAEAR1", "aln": "------------------------------------------MPTLG----VKGARERDKNSASGAGAGAGAGAGAGEKHRKGPRTTDPPKTGWALTKQRLVALSPTLRQRHLLFGDFLDDIGKVASMFPRESVELPYDMPDPRTWSQALNLPSEHQNRFLGLIKAAEARGRVHTLRLRYTRMRAEEISLLIQKQSSARAAIRLELFLPPQLKPTKIPDPLDRHERRRVETILEEEVDGNIFPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TD35-1", "uniprot_id": "LKAM1_HUMAN", "id": "Q8TD35-1", "name": "Protein LKAAEAR1", "aln": "------------------------------------------MPPPAKEGGRKGPRERSGKSAP--------GTAQGEERAKGAPATEPPKPGWALTPQGLAAMLPAQRHRHLLFGDLLEDVGAAASTFPCGSVEPGYRMPDPRPWTQSLELPAERQNRLLGVLKAAEARGRVRALRLRYTRMRAEEIALLIQRQKSARAAIRLELFLPPQLKPARIPDPLDRQERRRVETILEENVDGTIFPR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. . **.**: :**. :. **:: **. :*:***.***** : *.*: .: *:*****.*:*: : ..* ** *** * ***** *:*:*:**:*:***:**::********:::*************:****:* .*****************::*******:***********:***.****", "identical_positions": 122, "similar_positions": 45, "identity": "50.0%" }, { "cls_id": "homologset.agr.HGNC:33719", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBW3-1", "uniprot_id": "D3ZBW3_RAT", "id": "D3ZBW3-1", "name": "", "aln": "MEGVSALLASCPTAGLAGGLGVTACAAAGVVLYRIARRVKP-THTMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYMEHLNHVVSSVPSPRDPAQ--------PQQWVSSQVLLCRKCSHHQTTKIKQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVDYYIKHQN-RQLRALLLSHQFRR-REVDQAHGQSFSSS--AMKAPFQVILLRALAFLACAFLLSTALYGPGE--PFTPGAALPPALPPGGNSSAASDN-ATSQA----EGWQQLLGLLPEHATEKLHEAWAFGQSHQTGIVAVGLLTCLLAMLLAGRIRLRRIDAFSTCLWALLLGLHLAEHYLQAASPGWLDTLKFSTTSLCCLVGFTAAVATRKATGPRRFRPRRYFSGDSASLFLSSPSLAVPYPSVTASPASLFIPTPP-GFLPLSKQQLFRSPRRVSPSSLPGRLSRALSLGTIPSLTRTDSGYLFSGSRPPSRVSPAGEVSLSDYFSLLSSSFPSSPLPSPAPS--VASSVASSSGSLRHRRPLISPARLNLKGQKLLLF-SPPGEAPNTPSSS---EEHSPPNGSLF-IDPPQLLQRNRTRDTKHTVDTRSMLARDSAHSGHSIKKEDESSQSST-CIVDTTTKGCSEETTPWKARVSPSLVRGLLAVSLAVNALFTSAYLYQNLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A8U2-1", "uniprot_id": "TM201_MOUSE", "id": "A2A8U2-1", "name": "Transmembrane protein 201", "aln": "MEGVSALLASCPTAGLAGGLGVTACAAAGVVLYRIARRVKP-THTMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYMEHLNHVVSSVPSPRDPAQ--------PQQWVSSQVLLCRRCSHHQTTKIKQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVEYYIKHQN-RQLRALLLSHQFRR-READQAHGQSFSSS--AVKAPFQVILLRALAFLACAFLLFTTLYGPSE--PFTPGAALPPALPPGGNSSAASDN-TTSQA----EGWQQLLGLLPEHATEKLHEAWAFGQSHQTSIVAVGLLTCLLAMLLAGRIRLRRIDAFSTCLWALLLGLHLAEHYLQAASPGWLDTLKFSTTSLCCLVGFTAAVATRKSTGPRRFRPRRYFSGDSASLFPSSPSLAVPYPSVTSSPASLFIPTPP-GFLPLTKQQLFRSPRRVSPSSLPGRLSRALSLGTIPPLTRTDSGYLFSGSRPPSRVSPAGEVSLSDYFSLLSSSFPASPLPSPAPS--VASSVASSSGSLRHRRPLISPARLNLKGQKLLLF-SSPGEAPNTPSSS---EEFSPPNGSLF-IESPQLPQRNHTRDTKHTMEMRSMLARDSARSSHSIKKEDESSQSST-CVVDTTTKGCSEETTPWKARVSPSLVRGLLAVSLAVNALFTSAYLYQSLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SNT2-1", "uniprot_id": "TM201_HUMAN", "id": "Q5SNT2-1", "name": "Transmembrane protein 201", "aln": "MEGVSALLARCPTAGLAGGLGVTACAAAGVLLYRIARRMKP-THTMVNCWFCNQDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYLEHLNHVVSSAPSLRDPSQ--------PQQWVSSQVLLCKRCNHHQTTKIKQLAAFAPREEGRYDEEVEVYRHHLEQMYKLCRPCQAAVEYYIKHQN-RQLRALLLSHQFKR-READQTHAQNFSS---AVKSPVQVILLRALAFLACAFLLTTALYGASG--HFAPGTTVPLALPPGGNGSATPDNGTTPGA----EGWRQLLGLLPEHMAEKLCEAWAFGQSHQTGVVALGLLTCLLAMLLAGRIRLRRIDAFCTCLWALLLGLHLAEQHLQAASPSWLDTLKFSTTSLCCLVGFTAAVATRKATGPRRFRPRRFFPGDSAGLFPTSPSLAIPHPSVGGSPASLFIPSPP-SFLPLANQQLFRSPRRTSPSSLPGRLSRALSLGTIPSLTRADSGYLFSGSRPPSQVSRSGEFPVSDYFSLLSGSCPSSPLPSPAPS--VAGSVASSSGSLRHRRPLISPARLNLKGQKLLLFPSPPGEAPTTPSSS---DEHSPHNGSLFTMEPPHVPRKPPLQDVKHALDLRSKLERGSACSNRSIKKEDDSSQSST-CVVDTTTRGCSEEAATWRGRFGPSLVRGLLAVSLAANALFTSVFLYQSLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG66-1", "uniprot_id": "TM201_DANRE", "id": "A4IG66-1", "name": "Transmembrane protein 201", "aln": "MEALNQILIEYPPL-VVGGVGATAVAAGGALIYRIATRKKP-THLQVNCWFCNQDTVVPYGNRNCWDCPYCEQYNGFQENGDYNKPIPAQYMEHLNHGVSAG--VPETPK--------TLQWVNCQMLLCKKCNNNQTLKIKQLASFIPREDENYDEEIEVYKHHLEQTYKLCRPCQTAVEYYIKHQN-RQLRALLFNHQLRRTRDADKAFIKNTYS----LSTPAWLILLRILTFLACAFLVAVALSGYVDESPSVTQTLSGGVVPPKRVLQNENESKTDEGS----LMWDDLMGLLPEKAVENARLFWQSGSDHQMAVASVGLLTCITGVLMAGPVRLRRIDAVASVLWLLVICFYLAECYLKTDVPSWLEMVKFGITSVCCLVGFAAAVATRKSTSQRRARGRRYLSGGSPGEFFCN---HGPLLSAPVSESSTFIPTPPPNLSQLLIRQQSQRTRKASPSSLPGRLNRALSLGTIPSLARADSGFLFSGSRPSSQCKDS---PPSDYYSLKSGSRPSSPGPSPTPS--VAGSVTSTSSSARQRRPLISPARLNISGQKLRLF-SSPLEPFSLASPPPFLSEHNPMHSRGFLPDVPHFHLQNHG----------SVIDEGSVF-EHLEKPMGSSSSSSN-CHVDTTTGNNIESKPGWKGFLGMTLWPGLLFASLTINLSFICIYVYYNWR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBL2-1", "uniprot_id": "A1ZBL2_DROME", "id": "A1ZBL2-1", "name": "Ima1 N-terminal domain-containing protein", "aln": "------MLTLLIRLAATAIPVCAILFVAGTFLFKVYISIRSRYDARVNCWFCNGNVRVPYQDRNSWTCPSCEQYNGFTKDGDYNRDITSQRDCSLGSQKNSSKGSSSICANSYYSDVLTAQPPAPKNGLCDQCNEAQRLKVEKLSQFEPKNESRFDQELKVYRERLEKQFRLCSSCERHVNKVLHEKKKMVLSSKFLNYIIKGASLLKQPHFNRLAAAQKQFKLQRYRILMTILTVVNILCLLCRLPNATSIQFTTYLGKFIGLTLFYAYSHVLALIRVVTSSVGIFLEQREMIAKLLLYGRTFGKLLLYSLGIGQQQ-VQQATFASCFIGIYPYAMLALCFLHTIYDGLKFTRFTIALLLWSGYAMGIEFLDPYISGIS-FILVGSFVTLVLLATNRTNLLSQVNRDESACESFHRLCADECDDETLSMLSQQLSGYSDISN-SNLSMRTASVCHSPAPTISQRTIQAPASLLSLDSLHLSKQRMEQQAWSSNYGDASTVVAPRVQPAMMFQQKPMRPLESQWYRHGQSNLAQGNTFTRSTQNLLMPSRLPSINRNVGGADVSAWVAANQSVNQDLCTANLMRHYEEKQQNQLSRTSSQSSGFESQPRPEAQCGTGAATVRDYGWSEARESQRNFAVFPPMPSPTPTITPSEYQYSRTALPQQQPTMQPGDLLRKWIEINSKSSQPIH----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .. : ..*..:::: :. . ******* :. *** :**.* ** ******* ::****: *.:* *. .: . . * : ** :*.. * *:::*: * *::: .:*:*::**:.:**: ::** .*: *: ::.:: * : ::.: :: .:.. : : .. **: *:.: *: . .: . : ** . : * .:* : : :*: .: . : * :.:. * : : * : :*: . : . : .*.: * . : .* .. .. * . * : . . : . : . . .. ***.:: : . :*.. : : : :. . * * . ... : * . . :.. . *: * .: : :. . ... ... : : .: : .. . . : .. . . * * . : :: * * . . :: ", "identical_positions": 82, "similar_positions": 190, "identity": "11.83%" }, { "cls_id": "homologset.agr.HGNC:3372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY52-1", "uniprot_id": "D3ZY52_RAT", "id": "D3ZY52-1", "name": "", "aln": "MQLGEQLLVSSVNLPGAHFYSLESARGGGGGGGGGGGGGGGGSASLLPGAAPSPQRLDLDKASKKFPGSLPCQAGSAEPAGAGAGAPAAMLSDADAGDTFGSASAVAKPGPPDGRKGSPCAEEELP--------SAATAAATARYSMDSLSSERYYLPSPGPQGSELAAPCSLFQYPAAAGAAHGSVYPASNGARYPYGSMLPPGGFPAAVCPPARSQFGPATGSGSGAGSSGGGAGGPGGYPYGQGSPLYGPYAGTSAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQNFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPVTNKLDIGSYESEYSSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGAYQRKMAAGLPWTSRMSPPVFPEDQLAKEKVKEEISSSWVETPPSIKSLDSNDSGVYNSACKRKRLSPTTSSNGNSPPIKCEDINTEEYSKDTSKGMGAYYAFYTTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54839-1", "uniprot_id": "EOMES_MOUSE", "id": "O54839-1", "name": "Eomesodermin homolog", "aln": "MQLGEQLLVSSVNLPGAHFYSLESARGGGGGGGGGGGGGGG-SVSLLPGAAPSPQRLDLDKASKKFPGSLPCQAGSAEPAGAGAGAPAAMLSDADAGDTFGSTSAVAKPGPPDGRKGSPCAEEELP--------SAATAAATARYSMDSLSSERYYLPSPGPQGSELAAPCSLFQYPAAAGAAHGPVYPASNGARYPYGSMLPPGGFPAAVCPPARAQFGPAAGSGSGAGSSGGGAGGPGAYPYGQGSPLYGPYAGTSAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQNFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPVTNKLDIGSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGAYQRKMAAGLPWTSRMSPPVFPEDQLAKEKVKEEISSSWIETPPSIKSLDSSDSGVYNSACKRKRLSPSTPSNGNSPPIKCEDINTEEYSKDTSKGMGAYYAFYTSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95936-1", "uniprot_id": "EOMES_HUMAN", "id": "O95936-1", "name": "Eomesodermin homolog", "aln": "MQLGEQLLVSSVNLPGAHFYPLESARGGSGG-----------SAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDS-------------------SHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************.*******.** *.. **.******:**********.***.*:* *.***.*.**********:****:*.*::****************.***** :**:******************* **************** * *****.**.****.***********************.*:****.:*:*****.*.**.**** * *.**:******.*::********************************************************************************************************************************************************************************************************************* *************.**************************************************** ******.******:**************************************:************** **.**.****:********.***:***********.*****.*****:****:..** ***.*******:************.******:*", "identical_positions": 613, "similar_positions": 55, "identity": "85.61%" }, { "cls_id": "homologset.agr.HGNC:33720", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0U0-1", "uniprot_id": "A0A0G2K0U0_RAT", "id": "A0A0G2K0U0-1", "name": "", "aln": "MAAVKSPMQELKNANEPFDTMSPILLKSLVEEPKKRTEVPNHLLESKVYAKLLNNKVIQARPGIVHFGGYTIEKEHQQILNIANISDEDTHLHILPPQTKYFQISFEKKEHRLIPGLSLTVTITFSPDEWRYYYDCIRIHCKGDDTLLVPIHAYPVLNDLDFPTFINLSDVLLGESKSYVIPLQCSCPVDFEFHITLLRSHQAFTIEPKSGIIPANGEARVTVTFTPIQYGIAQIKIQLWISQFNSQPYECVFTGTCHPNIALPLEEFKRLNDR----SKKVNVPLEKT-AYVQFYPTVAQAKKPQKLKEIDYQDLRFPADLSNPFAVATVLNQEAGKMKIKDLKQVLDQGDEVSKTKQMKEAIFEQKVRQDIVTEIENHLKWQVHLGKEHTTYKFKKELIEERQKAREKYKQNRGDPIIGEELQRLQMKQSKKRIVHNLEEKVQEFHANFDPLINNMWLSRHRAQRRFQQAARKIMLERRLLLMLCAIREMDKEGIMRKLVQVKRSLVQAENPYRSLKVRVSQDDNLWPYSLQPEEVLHFAFPTDS--QSYNELALDGLGLVPIKSSDIQIKHNYPFFTLKVPQLYKIKGYHPFSVNKSSTNYRLQKLARPLKHGAEDEVTTIITLPKKN-TVQVSEKPS------------ILSMKPPEGLAMSVEYDPLYIFNPSPGLFTMKHPLTYEETLIDYHLCTHPKYKYTQEPHQGSSIPLTQKQFLHHTDIIPGIMNWKKFQPLVFSSMSE-SSKENTQRSDWYSPVMLPIDIPSPLEDLPEEDRLETTERDLCDQDIEVMLTPEMIQVEFPILTHRDSKKEKD---------------FKDPTQLPEKVGEKVQEEMKNLRNKALNTYLILD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A9Q751-1", "uniprot_id": "PCDP1_MOUSE", "id": "A9Q751-1", "name": "Cilia- and flagella-associated protein 221", "aln": "MEVVKSPMQELQQAKEPFDTMSPLLLKSLVEEPKKRTEVPNHLLESRVYAKLLNNKVIQARPGIVHFGGYEIESKHQQILNIANISDEDTHLHILPPQTKYFQINFEKKEHRLIPGLSLTVTITFSPDEWRYYYDCIRIHCKGDDTLLVPIHAYPVLNNLDFPTFINLSDVFLGESKSYVIPLQCSCPVDFEFHITLLRSHQAFTIEPKSGIIPANGKAKVTVKFTPIQYGMAQIKIQLWISQFNSQPYECVFTGTCYPNMALPLEEFKRLNTR----SKKVNVPLEKT-TYVQFYPAPAKAK-PQKLKEIDYQDLRFPADLSNPFAVATVLNQEPGKLKIKELKQVLDQGDEISKTRQMKEAIFEQKVRQDILTEIENHLKWQVHLGKEHTTYRFKRELTEEWKKARAKYKQNRGDPVEGEELQRLQTEQSQKRIVRDLKGKRQEFHPNFDPLVNNVWLTRHRAQRRFQQAARKIMLERRLLSMLGAIRGMDKESILRKIIQVNGKLIQGENPSRGRRAHLKQEDNIWRYSLESEEVLHFAFPTDS--ESYNELALDGLGLVPIKSPEIQIKHSYPYFTLKVPQLYKIKGYHPFSVNKSSTNYRLQKLARPLKHGAEDEVTTIITIPKKD-TTPLSAKPS------------ILSMKPPEGLAMSVEYDPLYIFNPSPGLFAVKHPLTYAETLIDYHLCSHPKYKYTQESHMGSSIPLTQRQFLHHTDIIPGIMNWKKFQPLVFSSMSDPSMVEATQRSDWYSSVMLPIDVPAPLEDLPEEDRLETTERDLCDQGIEVMLTPEMVQVEFPMLIHRDSKKEKD---------------FKDSTQLPEKVGERVQEEMKNLRSKALNTYLILD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0U5-1", "uniprot_id": "PCDP1_HUMAN", "id": "Q4G0U5-1", "name": "Cilia- and flagella-associated protein 221", "aln": "MAVVKTPSRGLKNAKEPFNNASPHLLKNLVEEPKKRKEVPNHLLESKVYAKLVNNKVIQARPGIIHFGGYQVEKQHQQILHLVNVSNEDTRVHILPPQTKYFEINYVRKEHHLVPGLSLTVTVTFSPDEWRYYYDCIRVHCKGDDTLLVPIHAYPVMNSLDFPSFINLSNVLLGESKTYVIPLQCSCPVDFEFYITLIQSHQAFAIEPTSGIIPANGKMTVTIKFTPFQYGTAQIKMQLWISQFNSQPYECVFTGTCYPNMALPLEEFERLNTL----SKKVNVPPEKAMMHINFHRPPAKPK-PQKVKEIEYQNLRFPVDLSNPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDIHEEMENHLKWQVHLGKDPMSFKLKKELTEEWQKACAKYKLDRGDPILDEEFQRLKTEVSHKRVVRNQEEKIKEFHPTFDPLINNTWLSRSRAQKRFQQVARKVMIQGRLFNMLSAVREMDKESILRKIGQAKQSIAQEANFFKFFLRRISQDDYTSRFSVSPKEVLPFAFPDCSPPQDSNELAPDGLGLVPIKSSEVQIKQSYSFFNLQVPQLYKIKRYQPFSVHKSSTSYRPQKLARALKQGAEDEVTTITALPKQDSTTQLSGKTS------------VLSMKPPEALAMSLDYDPLYVFNPNPGLFAVMHPLTYAETLIDYHLCSHPKYKFTKESRHGSSIPVTQKQFLHHTDIIPGIMHWKSFQSLVLSSLPDPSKMETTKSCDSFNSFMLPIDVPAILDALPEEDRLETVERELCEQNVEVMLTPEMIKVEFPMLNYKDIRKEKE---------------VKDQAQPAEKAGEKLLEEMRNLRGKALNTYLILE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RQR0-1", "uniprot_id": "A0A8M1RQR0_DANRE", "id": "A0A8M1RQR0-1", "name": "", "aln": "MEVVHSAPETFSKTVKRKNLLP---LSQLLEDTRTIATVPNHLLETKVFTTLKSNSVVQAEPSELHFSGFEVGKDYKKILKLVNVSSDVLSVHILPPQTKEFQIKYTKK-CRLVPGLAYTVTVFFRPDEWRYFSDNIRIHGKGEENLLVPVHAYPVINDLHIPSHISLPPVPLGQSTTHVIPLSCSCPVDFEFQVHCLQPHKAFTVRPLSGIIPANGKTVLKVTFTPLRYGTADITLQLIISQFNSKPVIWTVTGSSTPYLLLSKPDGNGDEEDDFADEQKTYGKYPTLTSHPKLKMTPYLDKGSKKKTKPVPQLQVSTTDVSTHAGLVKMLLQPQDKMRFKDLREAMSYTKVADQTREMKEAAFLKRVQQ--KEEKGNSIRWQVDLGDDPCSTELKLKILKEQDEAVAVYKLKYSG--ESVAISRPSTKLFSRRVLRHVG-QVPACTAVFSRYGTGQLEVRQRALRLFQQAARKVVLQCRMNKRLVSLRELVR----------KTRSQQGNN-------ESDLDEKSCLFILTPEKIRPFSFKTFISEDQADKPAAKAFRHVPAKTPEADMKLRTPLFTLKVPQQYRLMGYQPLSAYEAAASYIPPELSRPLRTGAQDELFPVVTCTSVDLSEDEEEKNPQEDDRADLSLNPTLSFCAPETLLKPPRAHPLRIFNPAPHVHAFKAAPLYLETDLDFYLCPLPRYTITSANVRGVDN-TTKKKVLDRQDIIKGIMTWKKFPSMALKSLSNISTLKIDCIP--HMSDMLPMEAPPVLQNLP--DNIRDEIQSGVSESSELRLTPEMVEAEFSLSERSSATSVKQEPVEGNSPTTPAARPISAEITTRDTHGQLPESTLTKLRARVLNRFKDFKSTGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 249, "similar_positions": 302, "identity": "28.42%" }, { "cls_id": "homologset.agr.HGNC:33722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5N4-1", "uniprot_id": "A0ABK0M5N4_RAT", "id": "A0ABK0M5N4-1", "name": "", "aln": "MRKPCDPLLWLCFSWLLLQHLVAWLLPGMKRPLSPPPSGEKEPPTTAASECPPHSPESSKPKRERKRPSYTLCDVCNIQLNSAAQAQVHCGGRAHQRRLRQLSLGKTSTGPAGPASSAPSPLLASLTLPTQPLQPPLDLKHLLAFHLNGTTPLSLFPNFSTMDPVQKAVISHTFGVPSPLKKKLFISCNICHLRFNSANQAEAHYKGHRHARKLKAVEAAKSKQRPRNL---------TTNGTVASTASPPASGSPGNPQSKDPASPPRGPSLQLPPTPDP-------STRDPAHSELS--DAAASSSSSSCPPCSPDPSREAPGPEPAEVAAGNGVNGEGRGEKGRLYCPTCKVTVNSASQLQAHNTGAKHRWMVEGHQGAPRRGRGRPVSRGGTGHKTKRVIGNRGGRQGPNPPFHCALCQLHVNSETQLKQHMSSRRHKDRLAGKPPKS-------------SSQHSKLQKHTALAVSVLK--------------SKLALQKQLTKTLAARFLPGPLPTTAAAICALPGPLTLRPAATAAATLFPAPVLGPALFRTPAGAVRPAAGPILFAPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A5E6-1", "uniprot_id": "Z385C_MOUSE", "id": "A2A5E6-1", "name": "Zinc finger protein 385C", "aln": "-----------------------------------------------------------------------------------------------------MLLG--------PASGSPSPLLASLTLPARPLQPPLDLKHLLAFHLNGTTPLSLFPNFSTMDPVQKAVISHTFGVPSPLKKKLFISCNICHLRFNSANQAEAHYKGHRHARKLKAVEAAKSKQRPRNP---------TTNGTVVSSASPPASGSPGTPQSKGPASPPLGPSLQLPPTPDPSAGDPVHSAGDPVHSELC--DAAASSSSSSCPPCSPDPSREAPGPEPAEGAVGSGVNGEGRGEKGRLYCPTCKVTVNSASQLQAHNTGAKHRWMVEGHQGAPRRGRGRPVSRGGTGHKTKRVIGNRGGRQGPSPPFHCALCQLHVNSETQLKQHMSSRRHKDRLAGKPPKS-------------SSQHNKLQKHTALAVSVLK--------------SKLALQKQLTKTLAARFLPGPLPTTAAAICALPGPLTLRPAATAAATLFPAPVLGPALFRSPAGAVRPAAGPILFAPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66K41-1", "uniprot_id": "Z385C_HUMAN", "id": "Q66K41-1", "name": "Zinc finger protein 385C", "aln": "-----------------------------------------------------------------------------------------------------MLLG--------PASGAPSPLLASLPLPTRPLQPPLDFKHLLAFHFNGAAPLSLFPNFSTMDPVQKAVISHTFGVPSPLKKKLFISCNICHLRFNSANQAEAHYKGHKHARKLKAVEAAKSKQRPHTQ---------AQDGAVVSPIPTLASGAPGEPQSKVPAAPPLGPPLQPPPTPDP-------TCREPAHSELL--DAASSSSSSSCPPCSPEPGREAPGPEPAAAAVGSSMSGEGRSEKGHLYCPTCKVTVNSASQLQAHNTGAKHRWMMEGQRGAPRRSRGRPVSRGGAGHKAKRVTGGRGGRQGPSPAFHCALCQLQVNSETQLKQHMSSRRHKDRLAGKTPKP-------------SSQHSKLQKHAALAVSILK--------------SKLALQKQLTKTLAARFLPSPLPTAATAICALPGPLALRPAPTAATTLFPAPILGPALFRTPAGAVRPATGPIVLAPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QV45-1", "uniprot_id": "A0A8M1QV45_DANRE", "id": "A0A8M1QV45-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------MLIG---------TAAQGSPLLASLPMQGRPLQTPLDLKHFLPFRLSGSSPLSLFPNFNNMDPVQKAVINHTFGVPQSLKKKQVISCNICHLRFNSTNQAEAHYKGHKHARKLKALEAQKNKQQRRQQDNSHHNREREKDRERDKERERVKASAPDPPPALLDDTAIEGTAVSDPESALRVDDAHCSSVVLTPISEVSSADLCASSPHSQHPDALLEPSGDTSPPPQDSPAADTPAEKEPKKSKQHLHCPICKVTVNSSIQMEAHNSGTKHKLMMDGQSVLPRR-RGKAMSSRPS-CKSKRLAS-KGSLGVASKSFYCEVCEIHVNSETQLSQHMNSRRHKDRLAGKPPKPKFNPHAKSQPTSTVSQGVRWNGYAGGAVSAMKKVISQCNLSSLSSQTKLVLQKQLTKNLTASFLPTPLTPPTLCTVAAN-PLALRHPP--GTTFIQTPILGPALFRPAPGPLRATHTPIIFSPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* ::. *******.: :***.***:**:*.*::.*::********..*********.******..**** .************:**********:*******:** *.**: : : . :.:*. * : :. *..:. * :. : . **: * .:**. *. * . :*. ::. * *... . * : .* :*:** *******: *::***:*:**: *::*: *** **:.:* : *:**: . :*. .. .*:* :*:::*******.***.***********.**. ** : : ::. *** :* :**.*******.*:* *** **...: . * **:** .. .:*:: :*:*******...*.:*.: **:::**", "identical_positions": 193, "similar_positions": 129, "identity": "33.51%" }, { "cls_id": "homologset.agr.HGNC:33724", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8ND94-1", "uniprot_id": "LRN4L_HUMAN", "id": "Q8ND94-1", "name": "LRRN4 C-terminal-like protein", "aln": "MLGSPCLLWLLAVT----------FLVPRAQPLAPQDFEEEEADETETAWPPLPAVPCDYDHCRHLQVPCKELQRVGPAACLCPGLSSPAQPPDPPRMGEVRIAAEEGRAVVHWCAPFSPVLHYWLLLWDGSEAAQKGPP----LNATVRRAELKGLKPGGIYVVCVVAANEAGASRVPQAGGEGLEGADIPAFGPCSRLAVPPNPRTLVHAAVGVGT-------------ALALLSCAALVWHFCLRDR-----------WGCPRR-AAARAAGAL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TYX2-1", "uniprot_id": "LRN4L_MOUSE", "id": "Q3TYX2-1", "name": "LRRN4 C-terminal-like protein", "aln": "MLGSLSLLWLAAMTT---------SLVSQPQILTLEDYQEGEEDDVTVATPSL-AVRCDYDRCRHLQVSCQELQKVGPVACLCPGLSREDQQPEPPRLGEVQIMAEEGYAVVHWCAPFSPVSHYWLLLWESNGAPQKSAP----LNATVRRAELKGLKPGVAYVLCVVAANDAGESNVPGAEVEGPENWTGPSFGPCRKFIMPPKPVTLVYAAVGVGT-------------ALALLSCAALVWHFCLRER-----------WGCPRRQGMAQASEAL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q499N6-1", "uniprot_id": "UBXN1_RAT", "id": "Q499N6-1", "name": "UBX domain-containing protein 1", "aln": "MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLSHILGREPTPSEQVGPEGSGSAAGESKPVLTEEERQEQTKRMLELVAQKQREREEREEREALEREKQRRRQGQELSAARQKLQEDEIRRAAEERRREKAEELAARQRVREKIERDKAERAQKYGGTVGSRSSPPATDPGPVPSSPRQEPPTKREYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVELHRGEEPGQDQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* * : *. . : *: . *: . * .: .: . .... * *: : :. *: *: :. . .:. : : . * ** * ** * .. * : :.* :. . . .. . ** * . : : . * *:.. * .: :. * *** ", "identical_positions": 30, "similar_positions": 56, "identity": "10.1%" }, { "cls_id": "homologset.agr.HGNC:33725", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUM7-1", "uniprot_id": "A0ABK0LUM7_RAT", "id": "A0ABK0LUM7-1", "name": "", "aln": "MEVGVRAALGLSLTSMTGLSLISPAWFQSPFSSYGVFTYCSWPQDDSWNQSCVTFWSLKDMPTLPWKVSAAMLLGGWLLLSLSALLLSAWALAPRRLFPRRGFGPTPVVQAAAAASTLVGLLVFPATLASPFAKEVCKGSSMYHSGTCWLSWGYAMAILNVVLTSLL-VIRW-QTTPVQRVAVPFSSDTQGVILVPE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UUA0-1", "uniprot_id": "LHPL7_MOUSE", "id": "Q3UUA0-1", "name": "LHFPL tetraspan subfamily member 7 protein", "aln": "MEVGVRAALGLSLTGMSGLSLISPAWFQSLSSSYGIFTYCSWPPGDCWNQSCVTFGSLKDMPSLAWKVSAATLLGGWLLLSISALLLSAWALAPRRLFARTGFGPTPVVQAAAAVSMLVGLLVFPATLASPFAKEICEGSSMYHSGACRLSWGYATAILNMVLTSLL-VIRW-QVTTVQRAAVPFSSETQRAILVPE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ICI0-1", "uniprot_id": "LHPL7_HUMAN", "id": "Q6ICI0-1", "name": "LHFPL tetraspan subfamily member 7 protein", "aln": "MLSSVWVALGLSLTCTSAFSLISPAWFQTPTFSFGILTYCSWPQGNSWNQSCVTFSSLEDIPDFAWKVSAVMLLGGWLLLAFNAIFLLSWAVAPKGLCPRRSSVPMPGVQAVAATAMIVGLLIFPIGLASPFIKEVCEASSMYYGGKCRLGWGYMTAILNAVLASLLPIISWPHTTKVQGRTIIFSSATERIIFVPEMNK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* .******* :.:*********: *:*::****** .:.******** **:*:* :.*****. ********::.*::* :**:**: * .* . * * ***.**.: :****:** ***** **:*:.****:.* * *.*** **** **:*** :* * :.* ** :: *** *: *:*** ", "identical_positions": 112, "similar_positions": 46, "identity": "56.0%" }, { "cls_id": "homologset.agr.HGNC:33727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYT2-1", "uniprot_id": "A0A0G2JYT2_RAT", "id": "A0A0G2JYT2-1", "name": "", "aln": "------MRNWCLCQICTCGRHRCPHGITRVYEHSGISCPTTEYMEKYPKYGDVLPPQSLKPKPGFQAYRGKMEGVTTFKSDYRP---YEVVKQPRHMPEEYKPKQGEIDLGTTYKRDFN-PYKVQPVVKVRPVERQEVKKGKLDTVPTYKDDYRSWDIQKCELCKPEQAYHPPDVKFGNSTTFQDDYVPREIQ---PRPSFKPCSVVKCPVGPFNGDTSHRRDYVPHQLEVKFARPKEVYKPTDQPFEDLTTHRNDFQGLT----GETAKICRPPYTRVTQNIQFKGSTEFRDSFQPWEIP---PPKVKKVAEYVPPSGSMQLDSTSHLDYVPYRASRVVAIRPVSHRRQSNFPFQGKSTMKEDFPAWESCRQGLIKQQQQIPNPSGKFEGLSTFRSHFVPHELIPT---ESCKPLNEALKSSVPLDDVTMYSIQFTP------------KKQEICPASYPSPPGYIFENTNSQGHKFFRKIIP-----AVKAF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQB6-1", "uniprot_id": "SAXO2_MOUSE", "id": "Q8BQB6-1", "name": "Stabilizer of axonemal microtubules 2", "aln": "------MRNWCLCQICTCG------------------------------------------------------------SDYRP---YEIVKQPRHIPEEYKPKQGKIDLGTTYKRDFN-PYKVQPLIKVRPVERQQVKKGKLDTVPTYKDDYRSWDIQKCELCKPEQAYHPPDVKFGNSTTFQDDYVPQEIK---PRQSFKPCSVVKCSVGPFNGDTSHRRDYVPHQLEVKFARPKEIYKPTDQPFEDLTTHRNDFQGLA----GETAKICRPAYTRVTQNIQFKGSTEFRDSFQPWEIP---PPKVKKVAEYVPPSGSMQLNSTSHLDYVPYQASRVVAIRPVSHRRQSNFPFQGKSTTKEDFPAWEICRQGLIKQQQQIPNPSGKFEGLSTFRSHFVPHELIPT---ESCKPLNEALKSSVPLDDVTMYSIQFTP------------KKQEICPASYPSPPGYIFENTNSQGHKFFRKIIP-----AVKAF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q658L1-1", "uniprot_id": "SAXO2_HUMAN", "id": "Q658L1-1", "name": "Stabilizer of axonemal microtubules 2", "aln": "-MGAKSMRSWCLCQICSCG------------------------------------------------------------SDYCP---YEIVKQPRHVPEEYKPKQGKIDLGTTYKRDLN-SYKVQPVAIVRPLER-QVKKGKLDTVPTYKDDYRAWDLHKSELYKPEQTYHPPTVKFGNSTTFQDDFVPQEIK---PRQSFKPSSVVKRSTAPFNGITSHRLDYIPHQLELKFERPKEVYKPTDQRFEDLTTHRCDFQGLI----GETAKLCRPVHTRVTQNALFEGSTEFRESFQPWEIP---PPEVKKVPEYVPPTGSMLLNSTSHLDYVPYQANHVVPIRPVSQKRSNNFPFQGKSIMKEDFPAWESCRQGLIKKQQQIPNPSGKFDGLSTFRSHYVPHELIPT---ESCKPLNIAFKSSVPFDDVTMYSVEYTP------------KRQEICPASYPSPPGYIFDNTNSQGHKFFRKIIP-----AVKAF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N8B9-1", "uniprot_id": "A0A8M1N8B9_DANRE", "id": "A0A8M1N8B9-1", "name": "", "aln": "------MTRLCICEMCSCGRHRCTHRPTTLYKKDPQTNVLSEYIEKYPPYKGHTRPKSLKPQLKYKAHQDTMDATTTFRTDYIP---YPVTHRPEKQQLEYKPKSGEIDLGTTYKQDFN-PYEVQPFTPLRPKERVHVVNAKLDTVPTYKEDFRQWEIIRRELTKPDTTYQPPATKFGNSTTFQDDFVHRGLV---PRESYKPSNVAKLSDTPFEKNTSNKLSYVPHPLEARYVKPPEEYKPSSHPFHDVTTHRQDYQGLP----SQSTKSCKPEPVKVASNKPFQSSTEFRDQYQHWPVS---LPQMQKSVEYTSPTANMDLTTTSHSDYIKHQIQPFVSSKPFSLPAKSSRPFQGNTTMRDDFQPWVAQRQSIIRKQAELQRPSGKMEDLTTFRAHFVQHEAQPS---FSFKPQNSPLHTDIPLQADTMYRTDFTP------------KKISMCPASFETPPGFVFENRDDQGHRFFRKMTSSDRIETPKEMVLTA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE97-1", "uniprot_id": "Q9VE97_DROME", "id": "Q9VE97-1", "name": "Stabilizer of axonemal microtubules 1", "aln": "MSGDCNTYCQNACDPCQAPTDFSPCPPNSTCPPCDCGDYAGCCYQQPP------RTMPILPKSHFMRSTAPLDTDTIYRRSFYANCGDNIRARPVMPCSQIRASTAPLEKCTIQKLSYMPPCPVKRTPPIVPMESGLRFEGPIYAMTSQKHDYVPKGIVKRDPIKPRVAICTSNAPMERCTIQKLSYMPIDVCQNPPPKAMVQGSHYCKPAGPMERCTIQKLSYMPVCLPAKEPTPWADKIRCVPPRYSNVCTTYNLSYMPNCNEARTAPVTPLTTLRFCGNDAGSGSTVYKLSYMPVDASRTKPAPVLPRDTFCRPSGPLERCTIQKLSYQPNCTERTPPIRPMENGLRFDGPMYAMTTQKHDFVAKPHVRRAPIMPRTAFCRPTGAMERCTVNKLSYMPVDVTCFPRAESVRPRQGFCRNEGPMEKCTTYKLSYLPNCVPPKEPLPWARYTSYCRPTGPIEKCTIQKLSYGPPGAFQRCGGPCGTGANDGTFPKAGIC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * . .: . : :* : :.. . :: * * . . *: : * * :. : ::.: *.*: : : : ** : .. . : ..* : .:: : * : . . *:: * :: .*:* * : * . . : . : ..:: :. * ..** :: .: . . : : *:. : : .: .* . . :*.. . *: . : :.** . *:. * : : .*:* :: :. : :: : * :* : :.. *:: * * .: * : . * .: : . . * * . : ", "identical_positions": 42, "similar_positions": 124, "identity": "8.4%" }, { "cls_id": "homologset.agr.HGNC:33728", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1X4-1", "uniprot_id": "A0A0G2K1X4_RAT", "id": "A0A0G2K1X4-1", "name": "", "aln": "MDPRGPAPQPFQQLEKPGRIRRRKTRRERNKALVSSHRPLARQDPPISSRDPCVIFQEPATSTAPKLVVITQGRLSREHRGLFNHEVKSLDVARLLNRGSLESCTPLLPTKSSCSPVRVQEPDLQSKGKENKVPGGSGPGPPNSPDLPVLGQLLEELQCQLVVPQAFPRRNLVQEARDTIIRTLQGCHGCVPDLALVLRGCQLPLPEAKRRAPERQRMAPSCINAPEHAPREGRQRTQQATKGCNFALPHTCSSITPAHRVSQVQPPDRQLPFLSSASSPSGAAWGPPTAFDMLKSIWLIATPPPP--QPWDVCPPQPLPQPSLPLLPRTSALDWSPNPPAPLPSLSWVVTQSSPEAWSFPPMRLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RW88-1", "uniprot_id": "PRR19_MOUSE", "id": "B2RW88-1", "name": "Proline-rich protein 19", "aln": "MDPRGPVPQPFQQLQKPGRIRRRKTRRERNKALVSSHRPLARQDPPISSRDPCVILQDPVASAAPKLVVITQGRLSREHRGLFNHEVKSLDVARLLNRGALESHTPQLPTKPSCSPVGVQEPDLQSKGKENKVPGGSGPGPPNSPDLPVLGQLLEELQYQLIVPQAFPRRNLVQESRDTIIRTLQGCHGCVPDLALVLRGCQLPLPEAKPRVPERQRMASSCMEVPEHAPREGKQRTQQATKGCDFAIPHTCNSTTPAHRGSQVQPPGHQLPFLSSASSPSGAAWGPPTAFDMLKSIWLIATPPPPPPQPWDVRPPQPLPQPPSPLLPRTSALDWSPNPPAPLPSLSWVVTQSSPEAWSFPPMRLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJB7-1", "uniprot_id": "PRR19_HUMAN", "id": "A6NJB7-1", "name": "Proline-rich protein 19", "aln": "MDTQGPVSQPFQQPEKPGRVRRRKTRRERNKALVGSRRPLAHHDPPVAIRDP------PVVPTASKLVVITQGRLSREHRGLFNHEVKSLDVARLLSSGTLVPGSPTLPAKPSPSPGRAQEPAPRSRDKENQVPGGSGPGPPSSPELSGVGQLLAELQCQLSLPQAFPRRNLIQDARDAIVHTLQACHGCVPDLALVLRGCQPPLPGAKPGVSER-KMTPFWINSPDQVPEQERQRKQQGTKEFTFPMPYTS-SMPTAHRGSLAPPRGPWPPYFPSLSSPSGTAWGPPTAFDLLKSIWLVATPPPP--RPWGVGLPQPLPQPSSPLLPRTSVLDWSPSPPSPLPSLSWVVAQSSPEAWSFPPMRLY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:**..***** :****:**************.*:****::***:: *** *...:*.*******************************. *:* . :* **:*.* ** .*** :*:.***:**********.**:*. :**** *** ** :*********:*::**:*::***.**************** *** ** ..** :*:. :: *::.*.: :**.**.** *.:*:*. * ..*** * . * . *::.* *****:*********:******:****** :**.* *******. *******.*****.**:*********:***************", "identical_positions": 242, "similar_positions": 76, "identity": "66.12%" }, { "cls_id": "homologset.agr.HGNC:3373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGW0-1", "uniprot_id": "A0ABK0LGW0_RAT", "id": "A0ABK0LGW0-1", "name": "histone acetyltransferase", "aln": "MAENVVEPGPPSAKRPKLS-----------------------SPALSASASDGTDFGSLFDLEHDLP-------------DELINSTELGLTNGGDI------------SQLQTSLG-----------IVQDAAS-------KHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQN------------SPGLSLINSMVKSPMAQTGLTSPNMG-MGSSGPNQGPTQSTAGMMNSPVN--------------------------------------------QPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRG-------RPNMQYPN---------------------AGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQS---HKMGMMSNPTPYGSPYTQNSGQQIGASGLGLQIQTKTVL---------PNNLSPFAMDKKAVTGGGMPNMGQQPTPSVQQP--GLVNPVAP------GMGSG------------AHTADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQS------------------------------------ILTGAPVGLGNPSS-------------------------------------------LGVGQQSTPSLSTVSQIDPSSIERAYAALG------------LPYQVNQIPPQPPVQAKNQQSQPSGQSPQGMRSMNNMS----------------------------------------ASPMGVN-------------------------GGVG----VQTPNLLSDSMLHSTINSQNPMMNENASVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQNMLPSAPGMVPVPMN--------------------------TAPNMGQQPTGMTTNGPLPDPSMIRGSVPNQMMPRMTPQP-----------------------------GLNQFGQMNIPQPP---------------------------------------------------------------IGPRQPSPLQHHGQLAQSGSLNPPMGYGPRMQQTSGQNQFLSQTQFPSQGMNVTNMPLAPSSSQAPVSQAQMSS-SSCPVNSPIMPPGSQGSHIHCPTLPQQA-HQNSPSPVPSRTPT-----PHHTPPSIGTQQPAATAIPAPVP--TPPAMPPGAQPQSLRPPSRQTPTPP-THLPPQVQP-----SLPVPP-ADQSQPQPRSQQSTAASVPTPTAPLLPPQPPTPLSQP-AVSVEG-----------QVSNPPS--------------------TSSTEVNSQTIPEK-----QPSQEVKMEVKMDVDQPEP----------------------------ADAQPDDTKE-----------------AKAEDGK--------VEPTETE--ERGPELKTEVKEEEDQPSTSA-----------------------------------------------AQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP-----------DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNSSPQYGLLADRYHFCEKCFNEIQGESVSLGDDPSQPQTT---------INKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEVIWPSGFVCDGCLKKTARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN-TSNESTD--------VTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGVPNVSNDLSQKLYATMEKHKEVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVAGQQQG-----LPSP-----TPATPTTPTGQQPATPQTPQPQPTSQPQPTPP------------------------------------NNMTP--------------------YLPRTQTAGPVSQGKAAGQVTPPTPPQTAQPP----------LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR----------PIQHQM---APMAPMGMNPP-------------PMARGPGGHLDPGMGP--------AG--------MQQQPP---WAQGGMPQPQQMQS-------------------GMP---RPAMMS----------VAQHGQPLNMAPQP-----------------GLGQVGVSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN---------SNPQPLPGQPGMPQGQ-----PGLQPPTMPGQQG--VHSNPALQNMN--------------PMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN----MNHNTMPSQFRDILRR-------------------QMMQQQ---GAGPGIGPGMANHNQFQQP-------------------------------------QGIGYPPQQQQQQQQQRMQHHMQQMQQGN--------MGQMGQLPQALGAEAGAS------------------------LQAYQQRLLQQQM-----GSPAQPN-PMSPQQHMLPNQAQ--SPHLQGQQIPNSLSN--QVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSP--QTSSPHP--------GLVAA-------------QAANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSADSADLSSNLSQSTLDIH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RWS6-1", "uniprot_id": "EP300_MOUSE", "id": "B2RWS6-1", "name": "Histone acetyltransferase p300", "aln": "MAENVVEPGPPSAKRPKLS-----------------------SPALSASASDGTDFGSLFDLEHDLP-------------DELINSTELGLTNGGDI------------SQLQTSLG-----------IVQDAAS-------KHKQLSELLRSGSSPNLNMGVGGPGQAMASQAQQN------------SPGLSLINSMVKSPMAQTGLTSPNMG-IGSSGPNQGPTQSPAGMMNSPVN--------------------------------------------QPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRG-------RPNMQYPN---------------------AGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQP---LKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVL---------PNNLSPFAMDKKAVPGGGMPSMGQQPTPSVQQP--GLVTPVAA------GMGSG------------AHTADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQS------------------------------------ILTGAPVGLGNPSS-------------------------------------------LGVGQQSTPSLSTVSQIDPSSIERAYAALG------------LPYQVNQIPPQPQVQAKNQQSQPSGQSPQGMRSVNNMS----------------------------------------ASPMGVN-------------------------GGVG----VQTPNLLSDSMLHSTINSQNPMMSENAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQNMLPNAPGMGPVPMN--------------------------TGSNMGQQPTGMTTNGPVPDPSMIRGSVPNHMMPRMTPQP-----------------------------GLNQFGQMNMPQPP---------------------------------------------------------------IGPRQPSPLQHHGQLAQSGSLNPPMGYGPRMQQASGQNQFLSQTQFTSQGMNVTNMPLAPSSGQAPVSQAQMSS-SSCPVNSPIMPPGSQGSHIHCPTLPQQA-HQNSPSPVPSRTPT-----PHHTPPSIGNQPPPATAIPTPVP--TPPAIPPGPQPPSLHPSSRQTPTPP-THLPPQVQP-----SLPAAPSADQSQQQPRSQQSTAVSVPTPTAPLLPPQPSTPLSQP-AVSIEG-----------QVSNPPS--------------------TSSTEVNSQTIPEK-----QPSQEVKMESKMEVDKPEP----------------------------ADAQPEDTKE-----------------AKGEDVK--------VEPTEME--ERGPELKTDGKEEEEQPSTSA-----------------------------------------------TQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP-----------DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN----------RYHFCEKCFNEIQGESVSLGDDPSQPQTT---------INKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPSGFVCDGCLKKTARTRKENKLSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN-TSNESTD--------VTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVAGQQQG-----LPSP-----TPATPTTPTGQQPATPQTPQPQPTSQPQPTPP------------------------------------NNMTP--------------------YLPRTQTTGPVSQGKAPGQVTPPTPPQTAQAP----------LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR----------PIQHQMPQMSPMAPMGMNPP-------------PMARGPGGHLDPGIGP--------AG--------MQQQPP---WAQGGMPQPQQMQS-------------------GMP---RPAMMS----------VAQHGQPLNMAPQP-----------------GLGQVGVSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN---------PNPQPLPGQPGMTQGQ-----PGLQPPTMPGQQG--VHSNPALQNMN--------------PLQAGVQRAGLPQQQPQQQLQPPMGAMSPQAQQMN----MNHNTMPSQFRDILRR-------------------QMMQQQ---GAGPGIGPGMAN--QFQQP-------------------------------------QGIGYPPQQQQQQ---RMQHHMQQMQQGN--------MGQMGQLPQALGAEAGAS------------------------LQAYQQRLLQQQM-----GSPAQPN-PMSPQQHMLPNQAQ--SPHLQGQQIPNSLSN--QVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSP--QTSSPHP--------GLVAA-------------QAANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSSDNADLNSNLSQSTLDIH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09472-1", "uniprot_id": "EP300_HUMAN", "id": "Q09472-1", "name": "Histone acetyltransferase p300", "aln": "MAENVVEPGPPSAKRPKLS-----------------------SPALSASASDGTDFGSLFDLEHDLP-------------DELINSTELGLTNGGDI------------NQLQTSLG-----------MVQDAAS-------KHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQS------------SPGLGLINSMVKSPMTQAGLTSPNMG-MGTSGPNQGPTQSTG-MMNSPVN--------------------------------------------QPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRG-------RQNMQYPN---------------------PGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVL---------SNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQP--GLVTPVAQ------GMGSG------------AHTADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQP------------------------------------ILTGAPVGLGNPSS-------------------------------------------LGVGQQSAPNLSTVSQIDPSSIERAYAALG------------LPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMS----------------------------------------ASPMGVN-------------------------GGVG----VQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQNMLPNAAGMVPVSMN--------------------------PGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQS-----------------------------GLNQFGQMSMAQPP---------------------------------------------------------------IVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSS-SSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPT-----PHHTPPSIGAQQPPATTIPAPVP--TPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQP-----SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQP-AVSIEG-----------QVSNPPS--------------------TSSTEVNSQAIAEK-----QPSQEVKMEAKMEVDQPEP----------------------------ADTQPEDISE-----------------SKVEDCK--------MESTETE--ERSTELKTEIKEEEDQPSTSA-----------------------------------------------TQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP-----------DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN----------RYHFCEKCFNEIQGESVSLGDDPSQPQTT---------INKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN-TSNESTD--------VTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQG-----LPSP-----TPATPTTPTGQQPTTPQTPQP--TSQPQPTPP------------------------------------NSMPP--------------------YLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPP----------LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR----------PIQHQMPPMTPMAPMGMNPP-------------PMTRGPSGHLEPGMGP--------TG--------MQQQPP---WSQGGLPQPQQLQS-------------------GMP---RPAMMS----------VAQHGQPLNMAPQP-----------------GLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN---------SNPQPIPGQPGMPQGQ-----PGLQPPTMPGQQG--VHSNPAMQNMN--------------PMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN----MNHNTMPSQFRDILRRQ------------------QMMQQQQQQGAGPGIGPGMANHNQFQQP-------------------------------------QGVGYPPQQQQ-----RMQHHMQQMQQGN--------MGQIGQLPQALGAEAGAS------------------------LQAYQQRLLQQQM-----GSPVQPN-PMSPQQHMLPNQAQ--SPHLQGQQIPNSLSN--QVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSP--QTSSPHP--------GLVAA-------------QAN-PMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNSDLNSNLSQSTLDIH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQU5-1", "uniprot_id": "A0A8M3AQU5_DANRE", "id": "A0A8M3AQU5-1", "name": "histone acetyltransferase", "aln": "MADNVLDSGPPTAKRPKLS-----------------------SPALSVSASDGNDFGSLFDLEHDLP-------------DELINSSDLGLPNGMDP------------SQLHTSLG-GGGMSGPLGVSGQDTAA-------KHKHLSELLRPGAPP-------SAST--ATGSPGN------------AASLGMMGGLSGGPVTQG------MGGPQQ-----QPSMMPQPGMVGGLN--------------------------------------------RAMMGTQKGN--GQPQ---------SMMGGQMMNGAPRMGYA-------NVNMNAGM---------------------AGNGNMLPDSLQQPNAGQQMA--QAAMRPQQPGAVNKMGMMGAPGPYGGSYGQCGGQ----SQLGPQLQNKAGQ---------PNSINQFNMDKKPQLGQNMGGMQGP----------GVVGGVS-------GPGGT----------AAPPAADPEKRK-LIQQQLVLLLHAHKCHRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKS-----------------------------------AGDKRNQQS------------------------------------LLGGAGMAMGGPLGG-----------------------------------------SLPGGQPSAPNINPPSQIDPSSIERAYAALG------------LTYQGNQASNQN--------QQTSVPGQPGMRSLNNMAG---------------------------------------GNSMGVN-------------------------GGVGAPMSNQHPGMLPDGMLHRNMTAQS-LMNDSSGVGNMGSAATATPPSAG-MRKSWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQ-------------------------------------------------------DGPHSDPSLVQATGPSQMVNRMQNPAG----------------------MPHSLNGMNQFGQVGMQQP----------------------------------------------------------------MGQRATPPLPMGANLNQMSMQGTPRMAQPNVPQLQNQYMQN-QFTGTGAGLGQGAVGLNQPAGQGAMPQNQMPTPPSLSVHSPVAQSQSS-VPVSGAAAGPQGPPSNHPPPAPQPGLH-----THCPPLRQNSPSPARSLTPTPAPHQTPPQLPGNQTPQPHTPNSSTTMAPPASQLPPMAQGVASEKSSQLQQQSHGGGATGGPQTGLASSVPSQNAHGLCTHPHSPLSQKSSATVDG-----------QASTPAS--------------------VSSADPSSQLTSSEPTAPLDSKTEVKQQDEEEENENETEDKASGKMAA----------------MQTEIKSEEKPE-----------------IKKEEPAGDECKTEPMETSTAE--DKKPEVKTEPKEEEVAGANST-----------------------------------------------PANTQS----KKKEFKPDELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPVRIRTSNKTNLDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQELGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPKYGLLADRYHFCEKCFNEIQGENVSLGDDPTQPQTS---------INKDQFQRKKNDTLDPELLLECGDCGRKMHQICVLHNETIWPSGFICDGCLKKSNSTRKENKYAAKRLPQTKLGNFLETRVNDYLKRQNHPESGEVTIRVVHISDKVVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGTDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRHLRTGVYHEILIGYLEYVKKMGFVMGHIWACPPSEGDDYIFHCHPSDQKIPKPKRLQEWYKKMLDKAVTERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENNTSSESID--------ATNGDSKNAKKKNNKKTSKNKSSLSRANKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRFIAGPAANSLPPISDPDTLMACDLMDGRDAFLTLARDKHLEFSSLRRAKWSSMCMLVELHNQTQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNVKGHEHKMEKLGLGLDDESNNQAAASTQNPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQETKCPVPFCLNIKHKLRQQQLQHRLQQAQMLRRRMATMQRVGQPPPCGGGPPGGLPSPGNNGATGPSTPTSVGTQPATPQTPTQLTPNLISLPQPGAGGVPAGAPQQSPQHPVHHQFQQMPGAGGMMNSQQQQMVPQQSLGQVPHPHNQYG-------PHPTGPSPNTQSQGKPGLGPATPPQLPSNPGTVPMAQQQQPTGPPAAAVEIAMKIQQVADAQRKMAQVQLLQRQAAQAGMM--PQH--HQ--QPQGQIGVAHPGIGMVGPQGLASQAQTSANRVQMEQQQGPQG---MMGAGP-------MQQQQPQQVAVQGQMPPQMHPQQPRMNPPL-QPQ-QQQWPGQGMPTQQRPAMMSQQGMVSMQ-PQPQPQQPSQQTQQQQAPQMPNRNALMSMVQAGLQSGVASGAAASNLPQGALQQLLRTLRSPSSPQQQQQVLNILRSSPLLMAAFIKQRVHKYKG-------GTGGPSGPQGGPGPMGGQPVGVNTGVPQPGMHLGQG--VNMQSQLLSQQQSQQQQQ---MQQRPLLQQQQVAALQQQQQQQQQQQQQQQQQQHQQQQQQ---QQHQQQQQQQQGIQGQGTPNMANPHFRELVMRRQQQLQFQQQQQQQQQQQQQQMSNHAAFQ-----QQQGYMSQQGNMQVPPGG-------QPLQGVQPGQQQNFPGNPAQQQAAAALQQRLAQQQHQL--------QMQQQQNAATQGPDMGPGGGPQPTQLGPGLQSP-----QALLQQALHQRLFPQQQ-HLSGTSPAQQNNPMSPQQ---QQISQ--SPHLQGQQLPSSLSN--QVCSPQ--PSPRPQSQPPHSSPSPRLQPQPSPHHISPQTQTGSPHPSHLQQHHSGMAPPPPPHQ-------QPQHNSKDPSGFG-ADQNAMLSQLS---GMAGLHGPGANDM-LPPSGQDLGINMNLTL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BE71-1", "uniprot_id": "A0A8M3BE71_DANRE", "id": "A0A8M3BE71-1", "name": "histone acetyltransferase", "aln": "MAENVLDSGPPSAKRPKLS-----------------------SPALSASASDGNDFGSLFDLEHDLP-------------DELISSSELSLANGGDL------------SQLHTSLGSGGGVIGGAVSGGQDAAA-------KHRQLSELLRHGSTP-------GAQQQGAMGNPG-------------GASMGLFGNMKVSPGTQS------MGPQGQQHLSMQAGLMQQQQMVDYLN--------------------------------------------RNMLGPQKGN--GQQQPGGPAPQHQNALASQMMNGSPRIGHH-------NPGMGN------------------------SNSNLLAEALQQQQQQQQTVGSQGGLRPQQPGAISKMGINAGSGPYGGPYSQSASQGLGVAGLAPQLQNKPGL---------PNSPAQFNLDKKPLPIHGIPGMQASQSSPVGAGGGGVAAGMVPNAQGSLGPGSAGSVVSAAVVGGVPPAADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQSE----------------------------------SMIATGGVALSSSMG------------------------------------------NVTGGSPSAPSLNTPGQIDPSSIERAYAALG------------LTYQGNQAPPQ--------------PVQQTQRPVNTMG----------------------------------------ANSMGVN-------------------------GAVGGQSQNQQSSLLQDTMLHLNMNSQS-LINDS-GVG---SLPMANPAASGSMRKSWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRAEYYHFLAEKIYKIQKELEEKRRTR--------LQKQGIMPSQAGMNPSGLQQAT-----------------------TGIGQPGPPTGLPSNGPLSDPAVVRPTGPNQMMNRMQNTA-----------------------------GMNSFGNHMGMQS----------------------------------------------------------------MGQRSTPPLNQGS-------MVPGRMPQPNVAQMQNQYMQTGPFQASSPVRSAGPVDLVHGGNDGAATQQGQMPLSSLPVGSPLAQPGSAGGAGSGSSVGSLGPSSMSAVPPSSTPTHSISL-SHCPPVHQNSPSPAHSRTPTPT--------PGSQTPQPHTPS-----------LPHLSSNGSQQQFPPSASSDSGMQPLGTPPAVSHSGLSTPNAS---QHPRTPLSHKGSLPVDG-----------QAATPAS--------------------VSSVEASFQQAPSDSTATLEPKEEVKAKDEEEEEAMEEERTAK----------------------EEDSKPEEKPE-----------------VKKEEPLSDGG---PMETASDE--DKKPEIKIEPKEEEEGSESAT-----------------------------------------------SQSSVSGATNKKKIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPSLLGIP-----------DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPKYGLLADRYHFCEKCFNEIQGETVSLGDDPSQPQTATIFLNISRSINKDQFEKKKNDTLDPELFVECMDCGRKMHQICVLHNETIWPSGFVCDGCLKKSNKTRKENKYAAKRLPQTKLGNFLETRVNAYLKRQNHPESGEVTVRVVHVSEKMVEVKPGMKSRFVDSGEMSESFPYKSKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRFLRTEVYHEILIGYLDYAKRQGFTTGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKAVAERVVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENSTSNESVE--------TTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLFAAPNSNALLPIVDPDPLMACDLMDGRDAFLTIARDKHLEFSSLRRSKWSTMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMDKLGLGLDDESNSQVASTTQNPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMVRRRMASMQRTGQQLPGGG---CGLPSPGNGCNTGPSTPTPS-TQPPTPQTPNQQCQ--PPATQPGVGNVPS--QQQQQLAGMAHQYQPISGSGGMINSSQQSMLPQQQQQPTPAQHLQNANNLPPYVQRPTGSSPHSQSMGKPGMVPGGFSQQQQSNLGQPVMPQHQPPGPPPAAVEIAMKIQRVAETQRQMAQQKILQRNQAPG-MM--PPHGLHQGPQTQNQMGINLPGTAMVGP----SQAQVAVARNQMDQQQG------MVTAG--------MQQQQP---GPRSQLPQVQLQQGQQGAPQL-QVSPQQQWTGPGMPPQQRPGVMNQMGLQGMAAPQHQQQQAVGQSQPQ------GNSGVMGMISS-QGGAAPAGAGPGNHSQAALQDLLRFLRLPSSPHQQQQVLSILRSNPLLMATFIRQRAPRYLGRGGPGAGGAGVPGGPGGGPGIMDGQQMNVNPNAAQGGMHMTQG--TTMQMNPLQQQQQQQQIQQRPMMSGNLQQQQQMAVLQQQQQQGVMPSQGTNISNIPPQLRE---MMRRHLQQQQQQQQQQ-----------------QQQQQQQQQQQQQQQQQHQQMGNHAQFQHPQPPQQQGYLGQSGIPPQQPGQPHPGGLQQQQGGAQPGTQQNYSGSVSHQQVAAALQHSLQQQQLQM--------QQQQSAMGGYQGADGGPGGGGPLQQQQQQMQSAPMGSQPQMFQQAIQQRLLQQQQSHLGGGSPAQHN-PMSPQQSQ-QQMSQ--SPHLQG-QLPNSLGN--QVRSPQ--PSPRPQSQPPNSSPSPRLQPQPSPHHISP--QTGSPHPGHLPQHHSGMAAPPPPQQQAQASQQQQQVNAMDQGPFG-ADQNVLLSQLS---GMGALHGQGTNDM-LTNN-QDMGSNINHSLDLM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MS40-1", "uniprot_id": "M9MS40_DROME", "id": "M9MS40-1", "name": "histone acetyltransferase", "aln": "MMADHLDE--PPQKRVKMDPTDISYFLEENLPDELVSSNSGWSDQLTGGAGGGNGGGGASGVTTNPTSGPNPGGGPNKPAAQGPGSGTGGVGVGVNVGVGGVVGVGVVPSQMNGAGGGNGSGTGGDDGSGNGSGAGNRISQMQHQQLQHLLQQQQQGQKGAMVVPGMQQLGSKSPNLQSPNQGGMQQVVGTQMGMVNSMPMSISNNGNNGMNAIPGMNTIAQGNLGNMVLTNSVGGGMGGMVNHLKQQPGGGGGGMINSVSVPGGPGAGAGGVGAGGGGAVAANQGMHMQNGPMMGRMVGQQHMLRGPHLMGASGGAGGPGNGPGGGGPRMQNPNMQMNFRPFAAQLNSLPYGVGQYGGPGGGNNPQQQQQQQQQQLLAQQMAQRGGVVPGMPQGNRPVGTVVPMSTLGGDGSGPAGQLVSGNPQQQQMLAQQQTGAMGPRPPQPNQLLGHPGQQQQQQQQPGTSQQQQQQQGVGIGGAGVVANAGTVAGVPAVAGGGAGGAVQSSGPGGANRDVPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFRQNHSVFQNANVPPGGGPAGIGGAPPGGGGAGGGAAGAGGNLQQQQQQQQQQQQNQQPNLTGLVVDGKQGQQVAPGGGQNTAIVLPQQQGAGGAPGAPKTPADMVQQLTQQQQQQQQQVHQQQVQQQELRRFDGMSQQVVAGGMQQQQQQGLPPVIRIQGAQPAVRVLGPGGPGGPSGPNVLPNDVNSLHQQQQQMLQQQQQQGQNRRRGGLATMVEQQQQHQQQQQQPNPAQLGGNIPAPLSVNVGGFGNTNFGGAAAGGAVGANDKQQLKVAQVHPQSHGVGAGGASAGAGASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLAEKIYKIQKELEEKRLKRKEQHQQMLMQQQGVANPVAGGAAGGAGSAAGVAGGVVLPQQQQQQQQQQQQQGQQPLQSCIHPSISPMGGVMPPQQLRPQGPPGILGQQTAAGLGVGVGVTNNMVTMRSHSPGGNMLALQQQQRMQFPQQQQQQPPGSGAGKMLVGPPGPSPGGMVVNPALSPYQTTNVLTSPVPGQQQQQQFINANGGTGANPQLSEIMKQRHIHQQQQQQQQQQQQGMLLPQSPFSNSTPLQQQQQQQQQQQQQQQATSNSFSSPMQQQQQGQQQQQQKPG--SVLNNMPPTPTSLEALNAGAGAPGTGGSASNVTVSAPSPSPGFLSNGPSIGTPSNNNNNSSANNNPPSVSSLMQQPLSNRPGTPPYIPASPVPATSASGLAASSTPASAAATCASSGSGSNSSSGATAAGASSTSSSSSAGSGTPLSSVSTPTSATMATSSGGGGGGGGNAGGGSSTTPASNPLLLMSGGTAGGGTGATTTTSTSSSSRMMSSSSSLSSQMAALEAAARDNDDETPSPSGENTNGSGGSGNAGGMASKGKLDSIKQDDDIKKEFMDDSCGGNNDSSQMDCSTGGGKGKNVNNDGTSMIKMEIKTEDGLDGEVKIKTEAMDVDEAGGSTAGEHHGEGGGGSGVGGGKDNINGAHDGGATGGAVDIKPKTETKPLVPEPLAPNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIP-----------DYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFNDIQGDTVTLGDDPLQSQTQ---------IKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKK-EAGAGEVHIRVVSSSDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKGQKKAKKSNKSKAAQ-RKNSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGS-ALADHKQANPQEARKQSIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALMSRTAAPAALQG--PAAVSGP-----TVVSGGVPVVGMSGVAVSQQVIPGQAGILPPG-----------------------------------AGGMSP----------------------STVAVPSPVSGGAGAGGMGGMTSPHPHQPGIG---MKPGGGHSPSPNVLQVVKQVQEEAARQQVSHGGGFGKGVPMAPPVMNRPMGGAGPNQNVVNQLGGMGVGVGGVGGVG--VGGVGGVGVNQLNSGGGNTPGAPISGPGMNVNHLMSMDQWGGGGAGGGGANPGGGNPQARYANNTGGMRQPTHVMQTNLIPPQQQQQMMGGLGGPNQLGGGQMPVGGQHGGMGMGMGAPPMAGTVGGVRPSPGAGGGGGSATGGGLNTQQLALIMQKIKNNPTNESNQHILAILKQNPQIMAAIIKQRQQSQNN--------AAAGGGAPGPGGALQQQQAGNGPQNPQQQQQQQQQQQVMQQQQMQHMMNQQQGGGGPQQMNPNQQQQQQQVNLMQQQQQGGPGGPGSGLPTRMPNMPNALGMLQSLPPNMSPGVSTQG---------GMVPNQNWNKMRYMQMSQYPPPYPQRQRGPHMGGAGPGPGQQQFPGGGGGAGNFNAGGAGGAGGVVGVGGVPGGAGTVPGGDQYSMANAAAASNMLQQQQGQVGVGVGVGVKPGPGQQQQQMGVGMPPG----------------------MQQQQQQQQPLQQQQMMQVAMPNANAQNPSAVVGGPNAQVMGPPTPHSLQQQLMQSARSSPPIRSPQPTPSPRS-APSPRAAPSASPRAQPSPHHVMS---SHSPAPQGPPHDG------------------MHNHGMHHQSPLPGVPQDVGVGVGVGVGVGVNVNVGNVGVGNAGGALPDASDQLTKFVERL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :: *. ** *:. * *: .*..*.. *. .: : . : .* .: * : .*:: : * :.:.: :*::*..**: . .. :.:...: . : : : . :. . : :.* * : . *. * . .* . . : : : .: . :* . *. .* *: : .*. . ::: . *:. *. . *:.** *****:********:***: * : . **: :*::**.** ** *: .*.* : ********: *:*.* . .* :* *::. **.: :** :: . ... . : * . . . * .. : * .** *. : *. * .: ...:*.* .... ..:* .: . . . . . .. .*.*:*.:* *****************.**::::*:**.***:**.*** **** *:.*:****:**************** .* :*:* * * :: * :: : .* : *. : * .. . * . :. * * * . . . . . .. . . . .. . *... . . . * . . . .: : :* * : . * . :.*.* .*: . . ... . *. . : : : : : : * :: :* : : ::* : : : .:: . . : ** *:*:*** **:**** ****:***:*** ****. **** ***:***.*:**.**: :::.*:*.:**:*:**:****:*************:**:**:**** ******* ******** *.**.*************** *:**** ** :*:****:***:.*:***** *.** *:*:**.. *** *: * :::* :**** ****** : ***.**:**.****. .***** ***** *:** ::*.*** :*::: .. :*** :*** *:* *******: ***:.*** :.***::********:** *:************:**.** *****:********:*: ** ******:**::*.*: *:. .*******************.********************.: **:::*****:*** **:* ** *********************:*****:::: : :. : ..**.*: :*: **:.*.*:: * *.**.. : .**** *:***************: : . :* ** ***.*:.************:*****:*******:::*::.** ***.* **:******.** ****:*****:*:****.* : .*:***:***:.:** * .* ::*: *********.******:*** ******** ******.****.*******************:*:* ******* ***:**:*** *:::** *::***:* *.*.. * :..* * : .. . .. : . * * ..* : . . : .: . .*.. .:::. ::*. * *: : : * :* ::: * .* *:* . * * :* : :*. . . * ::: :: .: .:*::* **: .* ::*::*:** . * * * . * . : * . * *** * : : . : : * . . .: : * * * .. * :*: : ** . .: : * : : :** *: .* . : *** ****. : .*.::**. :.******: . : ** * . . : *: :. :: .. * . ::. ", "identical_positions": 777, "similar_positions": 548, "identity": "22.59%" }, { "cls_id": "homologset.agr.HGNC:33731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A3M1-1", "uniprot_id": "A0A8I6A3M1_RAT", "id": "A0A8I6A3M1-1", "name": "", "aln": "MSAATAP--ERGWKSEKVDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTPVGQLPSTEIPARPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQ----------PHSQKMSPE-EVSAHDALIS---------KESDTPKLGHCSSPSGSEDSGINAIGAHYVESCDE--------DTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETMETTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6GQU0-1", "uniprot_id": "CC070_MOUSE", "id": "Q6GQU0-1", "name": "UPF0524 protein C3orf70 homolog", "aln": "MSAATAP--ERGWKSEKVDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTPVEQLPSTEIPAKPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQQ--------APHSQKMSPE-EVSAHDALIS---------KESDTPKLGHCSSPSGSEDSGINAIGAHYVESCDE--------DTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETMETTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NLC5-1", "uniprot_id": "CC070_HUMAN", "id": "A6NLC5-1", "name": "UPF0524 protein C3orf70", "aln": "MSAAASPASERGWKSEKLDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYMYQPMTPVEQLPSTEIPARPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQP--------APHSHRMSPE-EVSAHDALIS---------KESNTPKIDHCSSPSSSEDSGINAIGAHYVESCDE--------DTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETIETTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY84-1", "uniprot_id": "CC70A_DANRE", "id": "Q1LY84-1", "name": "UPF0524 protein C3orf70 homolog A", "aln": "MAASGGQ------KSEKLDEAQALARSCAGR-PDFLPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTSVCQLPSTAVPVAPSGHTHTMNLSISLAERFLRTAPKFQAPPCPESPKFCVISDLFVDDYMVKRINGKMCYVQRPPPPTPNPTHQPQTAAPQPVPQRSKNSHQVGPTVKQGQAKEKISAPKMDHCSSPSSSEDSGINALGLHYMESCDEDSCVDDDDEEEEDDELSTDGNSSPGSFWDQDECTLLSPSKSIVEIIEKIETTV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A3KNX6-1", "uniprot_id": "CC70B_DANRE", "id": "A3KNX6-1", "name": "UPF0524 protein C3orf70 homolog B", "aln": "MAYSGAQK---ALKSDKLDEAQALAKSCAGR-PDFLPCDGLSICATHSHGKCFKLHWCCYLGWCHCKYVYQPMTNVAQLPSTPVPAAPSDCPDTIDLSISLTERFLRISPCFQAPPCPESPKYCNIAELFIDDYIVKRINGKMCYVQRP-------QAHVEPAQMNPIQKQHTEDKQI--------VEETVKGPKMGHCSSPSTSEDSGINALGGHFLESCEE--------ESEEEDELSTDGHSSPGSLWDQDECTLLSPSKSMVEIIENIETTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : . **:*:*******:***.* *** ***********************:********:***** * ***** :*. * ..*:::*:**:*:**: :. **.* *:**::* *::**:*:* ** *********: .. .* : .. : : . **:.****** ********:* *::***:* : ** ***:: . ** * *: *********:* :*:**.:****", "identical_positions": 141, "similar_positions": 56, "identity": "51.09%" }, { "cls_id": "homologset.agr.HGNC:33732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBU1-1", "uniprot_id": "B1WBU1_RAT", "id": "B1WBU1-1", "name": "Protein phosphatase 1 regulatory subunit 42", "aln": "MVRLTVDLIAKN-SNLKPRKEETLVQCLKKITHINFSDRNIDSIDDLSLCKNLSVLYLYDNRISQVTNLNYTTNLTHLYLQNNCISCIENLSSLKKLEKLYLGGNYIAVVEGLEGLEELRELHVESQRLPLGEKLLFDPRTLRSLAKSLSTLNISNNNIDDIKDLEMLENLNHLIAVDNQLMHVKDLEVLLRKLMKLWKMDLNGNPVCLKPKYRDRLILMSKSLEFLDGKEIKNLERQFLMNWKASKEAKKISKKRRNRSEDQNNSYISNFETIHHIVPVYYPQVGKPKVVFFSDVQRYL--GKASSKFSQEDKTTITEDIGNLSLKESESLLTKTDIHEPHLLQNPKVKENLSENKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1Z4-1", "uniprot_id": "PPR42_MOUSE", "id": "Q8R1Z4-1", "name": "Protein phosphatase 1 regulatory subunit 42", "aln": "MVRLTVDLIAKN-SNLKPRKEETLAQCLKKITHINFSDRNIDSIDDLSLCRNLSVLYLYDNRISQVTNLNYTTNLTHLYLQNNCISCIENLSSLKKLEKLYLGGNYIAVIEGLEGLEELRELHVESQRLPLGEKLLFDPRTLRSLAKSLSTLNISNNNIDDIKDLEILENLNHLIAVDNQLMHVKDLELLLKKLMKLWKMDLNGNPVCLKPKYRDKLILTSKSLEFLDGKEIKDMERQFLMNWKASKDAKKISKKRRSRSEDASNSYISNFETVHHIVPVYYPQVGKPKVIFFSDVQRYLVHGNASSKCSQEDKTTITEDIGNLSLKESESSLTKNDIHEPHLLQNPKVKENLSEKKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4L9-1", "uniprot_id": "PPR42_HUMAN", "id": "Q7Z4L9-1", "name": "Protein phosphatase 1 regulatory subunit 42", "aln": "MVRLTLDLIARN-SNLKPRKEETISQCLKKITHINFSDKNIDAIEDLSLCKNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCIENLRSLKKLEKLYLGGNYIAVIEGLEGLGELRELHVENQRLPLGEKLLFDPRTLHSLAKSLCILNISNNNIDDITDLELLENLNQLIAVDNQLLHVKDLEFLLNKLMKLWKIDLNGNPVCLKPKYRDRLILVSKSLEFLDGKEIKNIERQFLMNWKASKDAKKISKKRSSKNEDASNSLISNFKTMHHIVPVYYPQVGKPKLAFFSEIQRYPVNANASPESS------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GQN5-1", "uniprot_id": "PPR42_DANRE", "id": "Q6GQN5-1", "name": "Protein phosphatase 1 regulatory subunit 42", "aln": "MVRLTVHLIAKLGSHSKSSRSESFQQYLRKLTHLNFSDKNIEEIDDLSVCRNLTVLYLYDNQISQICNLGFASNLTHLYMQNNNISCIENLSSLHKLSKLFLGGNSITVVEGLEELKSLKELHVEGQKLPCGEKLAFDPHSISSLSETLCILNISKNNIDELWDLAPLRKMTHLFAADNQLHDIQELETVFSQWFKLRLLDLSRNPVCHKPKYRDRLITVCKFLDDLDGKQINELSRQFLINWKASKDAKKKPEDGKDNKLQVANQLSTSAD--FHLGPQH-PSVRERS----SSLSKPSENEKPGVTFRTDQIQADSRGRG--TRGDSSTEWQSLKI--------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.***: *: *. :.*:: * *:*:**:****:**: *:***:*:**:******* ***: **.:::******:*** ******* **:**.**:**** *:*:**** * .*:*****.*:** **** ***::: **:::*. ****:****:: ** *.::.:*:*.**** .:::** :: : :** :**. **** ******:** .* *: ****:*:::.****:******:*** .:. ... : *. :. . .*: * : *.* : . *.:.: :.. ", "identical_positions": 154, "similar_positions": 94, "identity": "43.02%" }, { "cls_id": "homologset.agr.HGNC:33733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRF8-1", "uniprot_id": "D3ZRF8_RAT", "id": "D3ZRF8-1", "name": "Transmembrane protein 202", "aln": "MERRKEQAMTFYSPKVNKIKGDLKYQQPTLPTNKQ---SMSAQKRQQYLSEAYTYTRMFCASLSGFSLLLLICTSPMHWVQFLVTNNGLELNAGLWTLCNHELCWSHILKPPYYLQYSRALFIISVLCELIGLGLFFNSCRPTERIVSSELDLKVSMLSFCSAICLLLCLNLFLAQVEWHTKSAMESELLWTYYLNWSSDFLSVCAGIISFLNYITFQSHPPDGSVSEDLQQKYRLGFGPVPMTLPATAEMSPSKMPFLSGRQEKLRNVKRGKLATTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W35-1", "uniprot_id": "TM202_MOUSE", "id": "Q80W35-1", "name": "Transmembrane protein 202", "aln": "MER-KEQTMTFYSPEVIKIKGDLRYQRPTLPTNQQ---SVSTQKRQQYVNEACTYIRMFCGSLSGFSVLLLACTSPLNLVQFLVNNNGLELKAGLWTLCYHELCWSHTPKPPYYLQYSRALFLISILFMLISLGLLLSSCRPAERMMSAELDLKVSMLSFCSAVSLLLCLNLFLAQVELYTKNAMEYEFLWTYYLSWCSEVLYICVGIISFLNFITFQFHPPDEGVSADLWQKSRLGIGPVPKTLSATAERSRSEMQFLSGRQEKLQNVRKGKLATTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGA9-1", "uniprot_id": "TM202_HUMAN", "id": "A6NGA9-1", "name": "Transmembrane protein 202", "aln": "MERREHLTLTFHSPEVPKIKGNRKYQRPTVPAKKHPSASMSCQRQQQLMDQAHIYIRTLCGSLCSFSLLMLIAMSPLNWVQFLVIKNGLELYAGLWTLCNHELCWSHTPKPPYYLQYSRAFFLISVFTILTGLGWLFSSWILNRGSMTTNLDLKVSMLSFISATCLLLCLNLFVAQVHWHTRDAMESDLLWTYYLNWCSDIFYMFAGIISLLNYLTSRSPACDENVTVIPTERSRLGVGPVTTVSPAKDEGPRSEMESLSVREKNLP--KSGLWW----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :. ::**:**:* ****: :**:**:*:::: *:* *::** :.:* * * :*.**..**:*:* . **:: ***** :***** ******* ******* ***********:*:**:: * .** ::.* . ::::********** ** .********:***. :*:.*** ::******.*.*:.: : .****:**::* : . * .*: :: ***.***. . .*. * . *:* ** *:::* : * ", "identical_positions": 135, "similar_positions": 78, "identity": "48.39%" }, { "cls_id": "homologset.agr.HGNC:33736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKP1-1", "uniprot_id": "D3ZKP1_RAT", "id": "D3ZKP1-1", "name": "", "aln": "MDEGSEVSTDGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDQQSVGRAKMVKYLLENSADPNIQDKSGKSALMHACLERAGPEVVSLLLKSGADLSLQDHSGYSALVYAINAEDRDTLKVLLSACQAKGKEVIIITTAKSPSGRHTTQQYLNMPP-ADMDG--SHPPAT---PSEIDIKTASLPLSYSSETDLTLFGFKDRELSGSSDNTWDPDSPRRRPGMATNGPKLSQAPAWIKSTP-SLKHQARVASLQEELQDISPEEEVAYKTN-ALALSKRFITRHQSIDVKDTVHLLRAFDQVN-------------SRKMSYD-EINYHSLFPEGNQSC---VETPTDQDPDSSQ-IFASTLKNIVQKRNSGANHYSSDSQLAEGITPPTSEDGKAS--------KKKIFAPSPSLLSGSKELVETAPPGPLSRRNHAVLERRGSGAFPIDHSLAQSRPGFLPPLNVNPHPPITDIGVNNKICG-------LLSCGQKVLMPTAPIFPKEFKTKKMLLRRQSLQTEQIKQLVNF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UUF8-1", "uniprot_id": "AN34B_MOUSE", "id": "Q3UUF8-1", "name": "Ankyrin repeat domain-containing protein 34B", "aln": "MDEGSEVSTDGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDQQSVGRAKMVKYLLENSADPNIQDKSGKSALMHACLERAGPEVVSLLLKSGADLSLQDHSGYSALVYAINAEDRDTLKVLLSACQAKGKEVIIITTAKSPSGRHTTQHHLNMPP-ADMDG--SHPPAT---PSEIDIKTASLPLSYSSETDLTLFGFKDKELCGGSDNTWDPDSPPRKPVIATNGPKLSQAPAWIKSTP-SLKHQARVASLQEELQDITPEEEIAYKTN-ALALSKRFITRHQSIDVKDTAHLLRAFDQVN-------------SRKMSYD-EINYHSLFPEGSQTS---VEIPTDRDPDSNQ-IFASTLKSIVQKRNSGANHYSSDSQLAEGVTPPTVEDGKAA--------KKKIFAPSPSLLSGSKELVEPAPPGPLSRRNHAVLERRGSGAFPLDHSLAQSRPGFLPPLNVNPHPPITDIGVNNKICG-------LLSCGQKALMPTAPIFPKEFKTKKMLLRRQSLQTEQIKQLVNF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A5PLL1-1", "uniprot_id": "AN34B_HUMAN", "id": "A5PLL1-1", "name": "Ankyrin repeat domain-containing protein 34B", "aln": "MDEGMEISSEGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDHQSVSKAKMVKYLLENNADPNIQDKSGKTALMHACLEKAGPEVVSLLLKSGADLSLQDHSSYSALVYAINSEDTETLKVLLSACKAKGKEVIIITTAKLPCGKHTTKQYLNMPP-VDIDG--CHSPATCTTPSEIDIKTASSPLSHSSETELTLFGFKDLELAGSNDDTWDPGSPVRKPALAPKGPKLPHAPPWVKSPP-LLMHQNRVASLQEELQDITPEEELSYKTN-GLALSKRFITRHQSIDVKDTAHLLRAFDQAS-------------SRKMSYD-EINCQSYLSEGNQQC---IEVPVDQDPDSNQTIFASTLRSIVQKRNLGANHYSSDSQLSAGLTPPTSEDGKALIG------KKKILSPSPSQLSESKELLENIPPGPLSRRNHAVLERRGSGAFPLDHSVTQTRQGFLPPLNVNSHPPISDINVNNKICS-------LLSCGQKVLMPTVPIFPKEFKSKKMLLRRQSLQTEQIKQLVNF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJQ9-1", "uniprot_id": "A0A8M2BJQ9_DANRE", "id": "A0A8M2BJQ9-1", "name": "", "aln": "MEDSVEVRTDGNSLLKAVYLCRLRLTRLLLEGGAYINESNERGETPLMVACKSHHSDAQSVPKPKIIRYLLENGADPNIQDKSGKTALMHACMERAGEEVLSLLLSSGADPSLEDHTGSSALVYAVNAGDKDALRVLLDACKAKGKEVIIITTDKLPSGRQMTKQYLNVPPPPNLEDRLHCAPASCMCPSEIKLCTPHISPPTNNRSEINLGSTQTLPISKPGSPTQVSSPLQAASVAKLLHLQRLHSEPWLKIPSSLLLQQSKSSSLTEELLDITPEEELSFGYNGCRPPMKAMVARHQSIDIKDTTGLLRAFEMTSDAERERKNEQKWLSRKMSYDGELLPHSTSHQNLKQASITDTLPVERDPDCLPNLAISSLRNVFRRRNIGMDHYSSDSQLPQFGSQPSEDLGKTGGGGTGGVEKRKLVISRSSTLSGSRESLESLVQ----RRSPAMLERRGSGALLLDH-ISQTRPGYLPPL--NPHTPIPDIKANAGVGSKPVVGTAPIVAGSRHFVPCAPNHPRDYKNKKSLLRRHSMQTEQIKQLVNFEEIFGQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::. *: ::****:***: .*******************:*******:***::* * *** :.*:::*****.***********:******:*:** **:****.**** **:**:. ******:*: * ::*:***.**:*********** * *.*:: *:::**:** :::. .**: ****.: *. . . ...:::.* . : :. .. * ... . : :: .*:* .. * :* : :** *** **:****::: * . * :::******:***. *****: .. ******* *: :* :. : . *.::***. : *:*:.:.::** * :********. : *: : **: *:*:. . .* ** *:* :* **. *:********: :** ::*:* *:**** *.*.**.** .* : . : .*.: ::* .* .*:::*.** ****:*:*********** ", "identical_positions": 243, "similar_positions": 151, "identity": "43.78%" }, { "cls_id": "homologset.agr.HGNC:33737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1F6-1", "uniprot_id": "A0A8I6A1F6_RAT", "id": "A0A8I6A1F6-1", "name": "NHS-like protein 2", "aln": "MPFYRRTVVPQRLCPRNPPQPLAELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLYRRTVRLRRRLPCRLLGPEDDEELQAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLLGQTFR------SSDEAPEPTPSPRPQSAKRLEFVLMPAKWQLSEDETTTQGVRAPEACLSLCT-ADKQIAWNRPFPLPILKEKRWLQSCSIQSDLVPINTSGQQFDRHASFR---HSLFNTETAVNPKSTLRRRRTIIGFSNFSQRDQGHSSSPTGSLAHSATSDIRPGHPAPQVVQGRVAVGQEARFPSLTSPGLRHSSSEPGDTHQARSGPDPPSMESMAVVYSVPSSCNGPTESTFSASWKGDAFTYMTPSASNQGNQVSENGKNPSSGNS---WVPLNTLP--PLVPKEAATLFVTRDNPAG---CPGLPSYSEHPTLRRQIPERPPKIGLLPRGASRLETGPGGTN--RFRERSLSVPTDSG---VTSVDYDEEQKVN-----EARILPYASTSSEGSNSTDNIAALSTEQEARHR--RQRSKSISLKKAKKKPSPPMRSVSLVKDEPAVPPEGELVLP---KDQRPRSLCLSLEHQG--------HHPPHPDAQGHPAVPTFKDPEG-------TQFSHHWYLTDWKSG-DTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVASPGRPTGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSTSVRVRPVVPERKSSLPPTSPMEKICKSRLSFDLPLTSSTTLDLSGMSISIRSKTKVSRYHSDTNFGAKLVQKTSPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE-SPDYTEEPG----AEEVFTLPERKVKPPIAEKPPLARRPPSLVHRPSSLPGEYPLTSPTMAMTPRSSIPHMKQLPQDSYTVLRKPKSPSFPVGRSPGESTAASSLVFSPLASSSGAFFSG----TQQPPQASVEDGDPKVRALPERISLQSQEEAEKKMTKIPPPVPKKPSVLYLP---------------LTSPVAQMDACMAEPRLPFSPIITLEEDAKCPSTGDD-------QKSPGKR-----VTSTLHIDR------EKEATSPGRSVEPSAEEKSLIS-----DKTAEWIAED-DDDVFVAS---RTTEDLFTVIHRSKRKLLGWKETGEGFTGSRPSSHSPVKNTAESPTGESAAAPGPSGSACLDAGRNDDFKALLQKKGSKATPRTRPSAAELLKSTNPLARRIIAQFSKDYEP----TDNPST---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AXH1-1", "uniprot_id": "NHSL2_MOUSE", "id": "B1AXH1-1", "name": "NHS-like protein 2", "aln": "MPFYRRTVVPQRLCPRNPPQPLAELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLYRRTVRLRRRLPCRLLGPEDDEELLAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLLGQTFR------SSDGAPEPTPSPRPQSAKRLEFVLMPAKRQLSEDETTTQGVRAPEACLSLST-ANKQSAWNDPFPLPILKERLWLQPCSTQSDLVPINISGQQFDRHASFR---HSLFNTETAVNPKSTLRRRRTIIGFSNFSQRDQGHSSSPTGSLARSATSDIRPGHSAPQVVQGRVAVGQEARFPSLTSPGLRHSSSEPGDAHQARSASDHPGMESMAVVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSASSQGNQVSENGKNPSSGNS---WVPLNTLP--PLVPKEAATLFVTRDNPAG---CTGLPSYSEHPTLRRQIPERPPKIGLLARGTSRLETGPGGTN--RFRERSLSVPTDSG---VTSVDYDEEQKTS-----ETRILPYASTSSEGSNSTDNIAALSTEQEARHR--RQRSKSISLKKAKKKPSPPMRSVSLVKDEPALPPEGELVLP---KDQRPRSLCLSLEHQG--------HHPPHPDAQGHPAVPMLKDPGS-------TQFSHHWYLTDWKSG-DTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVASPGRPTGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSASVRVRPVVPERKSSLPPTSPMEKICKSRLSFDLPLTSSTTLDLSGMSISIRSKTKVSRHHSDTNFGVKLAQKTSPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE-SPDYIEEPG----AEEVFTMPERKVKPPIAEKPPLARRPPSLVHRPPSLPGEYPLTSPTMAMASRSSIPHMKQLPQDSYTVLRKPKSPSF-----PGESTASSSLVLSPLASSSGAFFSG----TQQPPQASVEDGGPKVRALPERIGLQSQEEAEKKMTKIPPPVPKKPSVLYLP---------------LTSPVAQMDACMAEPRLPFSPIITLEEDGKCPSTGDD-------QKSPGKG-----VTSPLHTDT------EKEAISPGRSVEPSAEEKSLIS-----DKTAEWIAEE-EDDVFVAS---RTTEDLFTVIHRSKRKLLGWKETGEGFTGSKPSSHSPVKNTADSPTGEAAAAPGPSSSACLDAGRNDDFKALLQKKGSKATPRTRPSAAELLKTTNPLARRIIAQFSKDYEP----TDNPST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HYW2-1", "uniprot_id": "NHSL2_HUMAN", "id": "Q5HYW2-1", "name": "NHS-like protein 2", "aln": "MPFYRRTVVPQRLCPRNPPQQLAELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLYRRTVRLRRRLPCRLLGPEEDEEELAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLVGQTFR------SSDEATKPTPNPRPQSARRLEFILMPTKRQLSEDETTTQGVRAPEASLSLSTTADKQTAWNSLFPLPILEEKRWPQLCSTQSDIVPINISGQQFDKHASLR---HSLFNTETAVNPKSTLRRRRTIIGFSNFSQRDQGHSNSPAGSVAHSTTSDIRPSHSVPEGVHGRVAVGQDARFPSLTSPVLRTPSSEPDEPHQARSGPNPPGMESMGMVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNS---WVSLNKVP--PLVPKEAATLLVARDNPAG---CSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLETGPGGAS--RFRERSLSVPTDSG---TTDVDYDEEQKAN-----EACALPFASTSSEGSNSADNIASLSAQQEAQHR--RQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALP---KDQRPKSLCLSLEHQG--------HHSSHPDAQGHPAIPNHKDPES-------TQFSHHWYLTDWKSG-DTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE-SPEYAEEPR----AEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSG----TQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLP---------------LTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDD-------LQSLGQR-----VTSTPQADS------EREASPLGSSVEPGTEEKSLIS-----DKTAEWIAED-DDDVFVAS---RTTEDLFTVIHRSKRKLLGWKEPGEAFVGGRTSSHSPIKNTAESPISESTATAGSGSSANLDAGRNDDFKALLQKKGSKATPRSRPSAAELLKTTNPLARRIIAQFSKDYET----TDNPST---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUJ8-1", "uniprot_id": "A0A8M3AUJ8_DANRE", "id": "A0A8M3AUJ8-1", "name": "", "aln": "MPFCKRTIVPKDVS-RSRGAVLTDLVDVCGLTLCAVLRQLSDLSRQSVSILEELEGELASICYRSGALENKLTSLQKHIAALATKPPAKTATNLDSESKR-----TAHFQSSWQQHVNVFGSWSRPECVQELHQEAQLNLQSLLQD-FEEQLYDNRVTGQTFKHPSSQSSEDTSTTLSRSPSSLNNKKTEFVFVPANKQVCEDETTTLGVRAQDP--SPCASEKTLLGWNAALSPPVAEKPRWYLGRQTPAQLVPIEITGQSFDKHAARHSELRATIRTDSAVNPK-TIRRPRSVVAGPDVTLHCQGDSKILAVDLIQGACS---PGSSQPRSLEPTTENTGQQHIP------LRKTQSDLEYSIPP-SPKTPSGMMDHATLMCPSPSWNGPKGSTFSPSWN-DSYNYALVTSPASKQPVTKTGMLTPGGDRGGLICPSQTSSGLSMSSGSHSSSFTSISEPCGHRVYTVSTQGSGVVTGKRNETEVTASTAVTRNSKSEQEKRSARSNVFRFRERSLSTPTDSGSFCSADNICSPGEAVSGVPEGESYALLYPSNSSEDSTSTDNVSVTTGSDFLPDGRLRSRSRSISLKKSKKKPPPPVRSVSLMKNLSEIRGMGSYQNEGHFRDGRPKSLFIPRDIQDSFQPEFLIAKPDDDTDQAHSSLETSSDISQPADRETELGFPPHWQLNEWKSNNDPYRSLSGSSTATGTTVIECMKVRGSSESLNSPSTSRATSPSQMSIEAET--KVSPFKPPCLLSPSSGYSSQSETPTPTISNTLLTG---PSPVGCKMRPKIPERKSSLPAS--AKDKSRSRLSFELPAN--AQLDLS----FVKPKPKASRRHSDTST-ANKPGKLSPSQSSLPMVTTTDLRNIRLRSVSRSELEDSPDGSSDIIEEEQSRDLSPPITPSNTKQPKPPVAMKPPLPKRPVNLTLKSPSS-------SPLTPESPPSSPVDRPMPVGNIYMVVRKPKPKRPAQASLSTSAIATQEPIRSHVSTFPEFDLEHGIPIEEDLPSPSSPEREDKCKTLPSRMTISCLAELDKRKPKVPPPVPKKPSVLLLPSPSIQTNGGAERQTLLSESISQSPTGTSASEIEGDLLKDEEEDYSAKQISHENHQIPELYETFGNEENDVVVEEYSSEDRGSHHFMERETPPAEIVKEIYTETEILEENISAVDKTELHITEETEDEVFVNTPTTHTTEDLFTIIHRSKRKVLGRKEPSDSFGRSQ-CLVSPVKSSSTDFRTLGLGTTPRSSS------RNENFMALLQKRSSKASSGTRVSAMELLKSTNPLARRVTEFSQSQPDGSAMNTPKPSSQDQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :**:**: :. *. *::* **. *: ::****:**. :*:::**:***.* :: *:.:* .: . *::::.. * . ::* * *** :***:* **** * .** .*:** :***********: :*** : *: ****: *.* :. : .* . . :: **:::*:: *:.****** **** :. * .: .. .** :. *: :: * . :::***: :**.**:**: : :: :.*::***** *:** *:::. .:.: : **.*. : .: :.: * *. . *. :. . : ::* ** ..*: . . * ..* . . : . ..* ***. ****.**: *::.* ::. . : *.:.* .. *: . :. . .: . . :: :.: .:*.* . . . :*: .* ... .: . *. *. .. :. ********.***** :. . : .. *: * :.*.***.*.*:**:: : .: . *.**:****:*:****.** *****:*: . : * :* **:** :. : *. :. . *.*.:: .* *. ** *.:***. *.*:***.************ :*:****** ********:***:***.*: ** :*. *:****************:* :* * *.. . ::** :********.: :. :*****:** . . **** ::.*.*.** **:*. .: * .*.*. :**** :***.:******:** **. : *.: ** : : . :: ***:* ***:.:** .*. :..* ** . .. ** . : * *:****. . .: *... : : .:: . :. :: *. * : * :.**.*: :.. * :*: *:*********** ** *:.. :* : : ..: . : *** .. ..: :: *: * . * *:*: . * :* : * . *** *:*: :*:*** : :*******:*******:** **..:.* .: . **:*.:: . . .:. ..* **::* *****:.***:. :* ** ****:*******: ..: : * :**: ", "identical_positions": 433, "similar_positions": 395, "identity": "32.53%" }, { "cls_id": "homologset.agr.HGNC:33738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1B0V2-1", "uniprot_id": "EZHIP_MOUSE", "id": "B1B0V2-1", "name": "EZH inhibitory protein", "aln": "MASSSSPERGLEALRDTDESEGEAPGPSGPRGRGGPSGAGSALRLRSLEAEMAAACVTSTAGEDLGTFSEPGSQHGDPEGGGGPDLELGHARPMMRSQRELGLTPKGGGKADQGGKGRKGGSGSPPHTKSSRKREQPNPNRSLMAQGAAGPPLPGARGSPAMPQPESSLSPRPDQSHHFDFPVGNLEAPGP-TLRSSTSQGSGSTPVPEALR------CAESSRAESDQSSPAGRELRQQASPRAPDDDDDGDGGPDPRGSGTPEGWVLRSGVVPFGRRSSASEVSPEEVRPEAQCTGWNLRPRPRS--------------SASAVSPEARPKAQSAGR-NLRPRPRSSASVVSPEARPKAQSAGRNLRPRPRSSASVVSPEARPEAQSAG-----RNLRPRATPRVPVAPSSTTRSSSDRGSSRAPRSR----SRSRSCSTPRLGSDHQRSRKIKMRLDLQVDREPESEAEQEEQELESEPGPSSRPQASRSSSRFAVPGRSSLAAEDSPPRRPVRMRASSPSPPGRLY-PLPKHYFEGVHSPSSSSSESSSVSSSHSPLNKAPDPGSSPPLSSLSGPNPFWLALIADLDNLDSSSPRVPGEEIEAAPHTREEEDKKCRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWI7-1", "uniprot_id": "F1LWI7_RAT", "id": "F1LWI7-1", "name": "", "aln": "--EGRKEGRKKERKEGRKQASKAPVASSVLTVCSGTSAAGSTFQG--VEVDLGEPETFSMAIENLGTFSVPDNQPFDPEGSFGPNIQLGRVRPMTRSQRELGQALRG----------EKDSNEPPAQTKSCRKRKQPSQN--LTTKSLGALQLPEALELPHRLQLPSSLSSQPSSSHHSEYAVGNLDSPGPTTLRSTTRSGPVSTPAPMALSQAFLTVSGPPSSASGSSSDENVQELSQQTILQAPDDGVFCRE-PDSRGSVIPGGWVLRSRVVTFG-HHSPALVSP-EVQPEVHTIGWNLRPRATPRIPVLHSGPPVSSPDTGSRATQSRSRSRSASRPGSDHRRRSRETKMEPEPEPEPKSESESDHELESESEAEAEPESEAEAEPESEAETEAESEAEAEPESEAEPEPESEAEPESEPEVEPESEPEVEAEVEPESEPEAEAEVEPESEPEVEAEAEAEPESEPESESEPELVEMEPGPRSQSQARPFTSTPTLPRRSSHATASSPPRRPVRMRASSPSPPGRLY-PLPGQYGEGASS-SSSSTSELCVSSPHSLKGSSPPLSDLSSVSGPS-PNTLWRALIPDLDNLHSSSERESEEETG---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86X51-1", "uniprot_id": "EZHIP_HUMAN", "id": "Q86X51-1", "name": "EZH inhibitory protein", "aln": "--MATQSDMEKEQKHQQDEGQGGLNN----------------------ETALASGDACGTGNQDPAASVTTVSSQASPSGGAALSSSTAGSSAAAATSAAIFITD--------------EASGLPIIAAVLTERHSDRQDCRSPHEVFGCVVPEGGSQAAVGPQ---------KATGHADEHLAQTKSPGNSRRRKQPCRN-------------------QAAPAQKPPGRRLFPEPLPPSSPGFRPSSYPCSGASTSSQATQPGPALLS----------HASEARP-ATRSRITLVASALRRRASG------------------PGPVIRGCTAQPGPAFPHRATHLDPARLSPESAPGPARRGRASVPGPARRGCDSAPGPARRG---------RDSAPVSAPRGRDSAPGSARRGRDSAPGPALRVR--------TARSDAGHRSTSTTPGTGLRSRSTQQRSALLSRRSLSGSADENPSCGTGSERLAFQSRSGSPDPEVPSRASPPVWHAVRMRASSPSPPGRFFLPIPQQWDESSSSSYASNSSSPSRSPGLSPSSPSPEFLGLRSISTPS-PESLRYALMPEFYALSPVPPEEQAEIESTAHPATPPEP-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . .:.. *. :. . . . :: .: . .. .*.*. . . . . . :. : : .. * : :*.. : : . . . * . : * : :.: .:** *. . . .: *. . * : .. . . : * :* .: . * .:.. . ** *. .. * : ... : : :.**. * . .. . * . .. : . : *. . :. : . . . . . . :. : .. . .. : :*. : .: * * . : ..* :.*************:: *:* :: *. * :*.:.. . *. * . :* . .:* * *:.: **:.:: * . . . * ", "identical_positions": 57, "similar_positions": 154, "identity": "9.18%" }, { "cls_id": "homologset.agr.HGNC:33739", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ18-1", "uniprot_id": "D3ZQ18_RAT", "id": "D3ZQ18-1", "name": "F-box only protein 50", "aln": "MACPAPPPPVNLDPRNHDPVVQTLGMEKIPDRDALSGRMEAEGSQNSEELPPHPQSPPPPPSPR---------SPTSPETPELPQPNAPTEFEARQLLVEEWGPVSGKLELPPSISWKLLFLERPLYRNLLNSPNPEGINIYQPAPPTG------PTRKP--LKELGNFRGWYITTENLQGPLS---------------WTVKEQCVNLLAKKLWEELLDDEQPDITIMDWFEDSRLDQCVYELHVWLLAADRRTVIAQHHVAPRTNGRGPPGRWVQVSHVFRQYGPGVRFVHFQHKTKNRMEPGGLRRTRVTDSSVSVQLRE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9C2-1", "uniprot_id": "FBX50_MOUSE", "id": "G3X9C2-1", "name": "F-box only protein 50", "aln": "-------------------------MEKTQDRDTLSGRMEAEGSLNSEELPPHPQSPPPPPSPR---------SPTSPVTPELPQPNAPTEVEARQLLVEEWGPLSGKLELPPRISWQLLFLERPLYRNLLSSPNPEGINIYQPAPPTG------PTRKP--LKELGNFRGWYITTQNLQGPLS---------------WTVKEQCVNLLAKKLWEELLDDEQPDITIMDWFEDSRLDQCVYELHVWLLAADRRTVIAQHHVAPRTNGRGPPGRWIQVSHVFRQYGPGVRFVYFQHKAKNRMEPGGLRRTRVTDSSVSVQLRE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZVX7-1", "uniprot_id": "FBX50_HUMAN", "id": "Q6ZVX7-1", "name": "F-box only protein 50", "aln": "-------------------------MEEVREGHALGGGMEADGPASLQELPPSPRSPSPPPSPPPLPSPPSLPSPAAPEAPELPEPAQPSEAHARQLLLEEWGPLSGGLELPQRLTWKLLLLRRPLYRNLLRSPNPEGINIYEPAPPTG------PTQRP--LETLGNFRGWYIRTEKLQQNQS---------------WTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDACVYELHVWLLAADRRTVIAQHHVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDSSVSVQLRE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568V3-1", "uniprot_id": "FBX50_DANRE", "id": "Q568V3-1", "name": "F-box only protein 50", "aln": "-----------------------------------------------------------------------------------------MATDWKQKCDSEWQLGAHGVPMPDTVDWKSVFETKPFERNLLQNPSPYGVNHTVPPPEPHRSGIPPPSDRPPQLEPEGNFSGWKTNTEVLPYDTSGIPPGVVICQLPQHRWFTLEQCVDLKAAGLWDQLLDDFQPEIVIEDWYEESQLHKCIYQLDVKLLGADGETVIKQHTYNPEEDLECYSHTWKKVSHVFSKYAPGVRYIHFLHRLKNQFMVEFFN-TKVTDSSVIVKASKPSVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* .** : : :* : *: :: :*: **** .*.* *:* *.* . *: :* *: *** ** *: * * * . :***:* * **::**** ** *.: **:*:*:*. *:*:*.* **.** .*** ** *. . . . * :***** :*.****:::* *: **:: :. *:****** *: : ", "identical_positions": 84, "similar_positions": 55, "identity": "25.69%" }, { "cls_id": "homologset.agr.HGNC:3374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHS1-1", "uniprot_id": "EPAS1_RAT", "id": "Q9JHS1-1", "name": "Endothelial PAS domain-containing protein 1", "aln": "----------------------------------------------------------MTADKEKKRSSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDN--------------------------LYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLKTGSGFGKKNKDR------STERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVYNNCPPHSSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELVGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVVYNPRNLQPQCIMCVNYVLSEIEKNDVVVSMDQTESCSSH----------------------------------------------------------------------------------------------------------------------------------------------------------------------TLMAMNSIFDTSDDVALSEKSNY-----------------------LFTNLKEEPEDLAQLAPTP-------------------GDAIISLDFGSQNFDESSTYGKAILPPGQ--PWATELR-SHSAQSESRSLP-AFTVPQAGSPGNATPSAT---SSSS-CSTPSSPEDYYSSLENHLKIEVIEKLFAMDTEAKDQCSTQTDFN---------ELDLETLAPYIPMDGED-FQLSPICPEEPLVPESP------------------QPNPQHCFSTMSSIFQPLTPGASQGTFFLDKYPQQLESRKTESEHWPMSTIFFDAGSKGSLPPC-------------------------CGQASTPLSSMGGR-------------------------------------------------------------------------------SNTPWPPDPPLHLGPTKWSVGNQSAEPLGPLPLGTSQLEPPSTPP----------------------------------------------HVSMFKMRSAKDFGARGPYMMSPAMIALSNKLKLKRQLDY--EEPAFQDTSGGDPPGTSSSHLMWKRMKSLMGGTCPLMPDKTVSASMAPDEFTQKSMRGLGQPLRHLPPSQPPSTRSP-----GENAKSGFPPQCYASPFQDYSPPGAQKGSGVASRLLGP--------SFEPYLLPELTRYDCEVNVPEPGSSTLLQGRDLLR--------------------ALDQAT---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97481-1", "uniprot_id": "EPAS1_MOUSE", "id": "P97481-1", "name": "Endothelial PAS domain-containing protein 1", "aln": "----------------------------------------------------------MTADKEKKRSSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDN--------------------------LYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLKNGSGFGKKSKDV------STERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVYNNCPPHSSLCGSKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------HLMAMNSIFDSSDDVAVTEKSNY-----------------------LFTKLKEEPEELAQLAPTP-------------------GDAIISLDFGSQNFDEPSAYGKAILPPGQ--PWVSGLR-SHSAQSESGSLP-AFTVPQADTPGNTTPSAS---SSSS-CSTPSSPEDYYSSLENPLKIEVIEKLFAMDTEPRDPGSTQTDFS---------ELDLETLAPYIPMDGED-FQLSPICPEEPLMPESP------------------QPTPQHCFSTMTSIFQPLTPGATHGPFFLDKYPQQLESRKTESEHWPMSSIFFDAGSKGSLSPC-------------------------CGQASTPLSSMGGR-------------------------------------------------------------------------------SNTQWPPDPPLHFGPTKWPVGDQSAESLGALPVGSSQLEPPSAPP----------------------------------------------HVSMFKMRSAKDFGARGPYMMSPAMIALSNKLKLKRQLEY--EEQAFQDTSGGDPPGTSSSHLMWKRMKSLMGGTCPLMPDKTISANMAPDEFTQKSMRGLGQPLRHLPPPQPPSTRSS-----GENAKTGFPPQCYASQFQDYGPPGAQKVSGVASRLLGP--------SFEPYLLPELTRYDCEVNVPVPGSSTLLQGRDLLR--------------------ALDQAT---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99814-1", "uniprot_id": "EPAS1_HUMAN", "id": "Q99814-1", "name": "Endothelial PAS domain-containing protein 1", "aln": "----------------------------------------------------------MTADKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDN--------------------------LYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKSKDM------STERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------HLMAMNSIFDSSGKGAVSEKSNF-----------------------LFTKLKEEPEELAQLAPTP-------------------GDAIISLDFGNQNFEESSAYGKAILPPSQ--PWATELR-SHSTQSEAGSLP-AFTVPQAAAPGSTTPSAT---SSSSSCSTPNSPEDYYTSLDNDLKIEVIEKLFAMDTEAKDQCSTQTDFN---------ELDLETLAPYIPMDGED-FQLSPICPEERLLAENP------------------QSTPQHCFSAMTNIFQPLAPVAPHSPFLLDKFQQQLESKKTEPEHRPMSSIFFDAGSKASLPPC-------------------------CGQASTPLSSMGGR-------------------------------------------------------------------------------SNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAPLG-----PPVSPP----------------------------------------------HVSTFKTRSAKGFGARGPDVLSPAMVALSNKLKLKRQLEY--EEQAFQDLSGGDPPGGSTSHLMWKRMKNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHLPLPQPPSAISP-----GENSKSRFPPQCYATQYQDYSLSSAHKVSGMASRLLGP--------SFESYLLPELTRYDCEVNVPVLGSSTLLQGGDLLR--------------------ALDQAT---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UR89-1", "uniprot_id": "A0A8N7UR89_DANRE", "id": "A0A8N7UR89-1", "name": "", "aln": "----------------------------------------------------------MTAEREKKRHPSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHSISSHLDKASIMRLAISFLRTRKLFSSGQTVQQMRSQNGSQMDN--------------------------LYLKSLEGFVIVVTSDGDMIFLSENVSKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSIKSGPVYSRKGKEM------STSRDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLQVCSSRPPQ-ILCGFSEPPLTCITMLCAPIPHPSNVDTPLDSKTFMSRHSMDMKFIYCDERVSSLIGYRPEELLGRSVYEFCHALDSENMTKSHQNLCNKGQVVSGQYRMLAKNGGYVWVETQATVIYNNRNSQPQCIICINYILSSVEEQSVIFSLDQTEALFKPY---------------------------------------------------------------------------------------------------------------------------------------------------------------------HTYDMGEIFSQN--TSISEPQNN-----------------------LFTTLKEEPEELAQLAPMP-------------------GDAIIALDFERAEFEEATFFSKSSKLPAVGPSWVVDTPPDGSPERNLSSLPSSFTVPQVPPAGKCTPCTTPCLSSCSSCSTPSSPVDCCGSGEWDLKVELTEKLFASESGATNPTDSQLNLS---------DLDLETLAPYIPMDGED-FQLHPICLEEPVPDAGPGL----------------SAAVQHSFSSVADLFQPLG-----------QYPPYNKNR---------PSTCPDAT---HIQPY-------------------------QTTPNIPLSSEKQR-------------------------------------------------------------------------------QSLHWPPDQLSQYEHTNVGCMDDRNTGGPGQACN-----FNVPPP----------------------------------------------HQRFFENFTPVQKG------MSLGQRALLNNFKRKRQSEFP-LSCSFSDIPKQVVAPHKSTDGMRKRMKPMNDDSCAFSVRKSLSTSVLTDKFPCMQS-GLVD-----PQACSRSVKGC-----PEDLKQHCTDSFCSNSSRQYNMMPSRKHTGMISQLLAP--------SFDSYCLPELTRYDCEVNMPLQGNLHLLQGSDLLR--------------------ALDQST---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24167-1", "uniprot_id": "SIMA_DROME", "id": "Q24167-1", "name": "Protein similar", "aln": "MVSLIDTIEAAAEKQKQSQAVVTNTSASSSSCSSSFSSSPPSSSVGSPSPGAPKTNLTASGKPKEKRRNNEKRKEKSRDAARCRRSKETEIFMELSAALPLKTDDVNQLDKASVMRITIAFLKIREMLQFVPSLRDCNDDIKQDIETAEDQQEVKPKLEVGTEDWLNGAEARELLKQTMDGFLLVLSHEGDITYVSENVVEYLGITKIDTLGQQIWEYSHQCDHAEIKEALSLKRELAQKVKDEPQQNSGVSTHHRDLFVRLKCTLTSRGRSINIKSASYKVIHITGHLVVNAK-------------GERLLMAIGRPIPHPSNIEIPLGTSTFLTKHSLDMRFTYVDDKMHDLLGYSPKDLLDTSLFSCQHGADSERLMATFKSVLSKGQGETSRYRFLGKYGGYCWILSQATIVYD--KLKPQSVVCVNYVISNLENKHEIYSLAQQTAASEQKEQHHQAAETEKEPEKAADPEIIAQETKETVNTPIHTSELQAKPLQLESEKAEKTIEETKTIATIPPVTATSTADQIKQLPESNPYKQILQAELLIKRENHSPGPRTITAQLLSGSSSGLRPEEKRPKSVTASVLRPSPAPPLTPPPTAVLCKKTPLGVEPNLPPTTTATAAIISSSNQQLQIAQQTQLQNPQQPAQDMSKGFCSLFADDGRGLTMLKEEPDDLSHHLASTNCIQLDEMTPFSDMLVGLMGTCLLPEDINSLDSTTCSTTASGQHYQSPSSSSTSAPSNTSSSNNSYANSPLSPLTPNSTATASNPSHQQQQQHHNQQQQQQQQQQHHPQHHDNSNSSSNIDPLFNYREESNDTSCSQHLHSPSITSKSPEDSSLPSLCSPNSLTQEDDFSFEAFAMRAPYIPIDDDMPLLTETDLMWCPPEDLQTMVPKEIDAIQQQLQQLQQQHHQQYAGNTGYQQQQQQPQLQQQHFSNSLCSSPASTVSSLSPSPVQQHHQQQQAAVFTSDSSELAALLCGSGNGTLSILAGSGVTVAEECNERLQQHQQQQQQTSGNEFRTFQQLQQELQLQEEQQQRQQQQQQQQQQQQQQQLLSLNIECKKEKYDVQMGGSLCHPMEDAFENDYSKDSANLDCWDLIQMQVVDTEPVSPNAASPTPCKVSAIQLLQQQQQLQQQQQQQQNIILNAVPLITIQNNKELMQQQQQQQQQQQQEQLQQPAIKLLNGASIAPVNTKATIRLVESKPPTTTQSRMAKVNLVPQQQQHGNKRHLNSATGAGNPVESKRLKSGTLCLDVQSPQLLQQLIGKDPAQQQTQAAKRAGSERWQLSAESKQQKQQQQQSNSVLKNLLVSGRDDDDSEAMIIDEDNSLVQPIPLGKYGLPLHCHTSTSSVLRDYHNNPLISGTNFQLSPVFGGSDSSGGDGETGSVVSLDDSVPPGLTACDTDASSDSGIDENSLMDGASGSPRKRLSSTSNSTNQAESAPPALDVETPVTQKSVEEEFEGGGSGSNAPSRKTSISFLDSSNPLLHTPAMMDLVNDDYIMGEGGFEFSDNQLEQVLGWPEIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. ::** .* ******************:* **: *** . .:*****:**::*:**: ::::. : .: . : .:::. * ::::**: *:: :**: ::***: :::*:*::: *:.*::::* *** **:* *::* *.: : **:*:*:***:*.***::*:***::**:* **:: * . : : ** ***::: **.:.**:::**:**:* * *::: .*:** *::**. * :. *. ***.: :.:.: .*** :.:**:*.* *** *: :*.*::*: : :**.::*:**::*.:*:: : *: * : . * . . ::: : :* *****::*:: . . * .::. *: : : ... . . . *.: . . * : .*: .... .. . . .. . : . . : ** . : :* . : .* :*.. .: ** *.: .:. . . .. : :.:: . :* * : :. . * : * . .** . * : . :: : . ..* : : :. . * *. * : : . . . . :::: . .. : * .: * . * . . . . : * . :. . .:. . : :: .: * ** : . . : . *:.* :: :**::. ", "identical_positions": 174, "similar_positions": 280, "identity": "11.43%" }, { "cls_id": "homologset.agr.HGNC:33741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKQ1-1", "uniprot_id": "A0A8I6AKQ1_RAT", "id": "A0A8I6AKQ1-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "aln": "------MQLCQ-------GASSMAAAEV-PGYLVSPQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESVPPDWPYYLAIDRILAKVPESCEGKLPDGQQPGPSTSQTEASLSPSAKSTPLYLPYTQCSYE----------GRFEDDRSDSSSSLLSLKFRSEERPVK------KRKMRSCHLQKKK-----------------------LRLLEAMLEEQRRLSRAMEETCREVRRVLDQQN--------ILQVQSLQLQERMMSLLEKIIAKSNV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIL2-1", "uniprot_id": "MSD1_MOUSE", "id": "Q8BIL2-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "aln": "MVRWPGLRPCLSAILNPAGASNMAAAEV-PGYLVSPQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESIPPDWPYYLAIDRILAKVPESCEGKLPDGQQPGPSTSQTEASLSPSAKSTPLYLPYTQCSYE----------GHFEDDRSDSSSSLLSLKFRSEERPVK------KRKMRSCHLQKKK-----------------------LRLLEAMLEEQRRLSRAMEETCREVRRVLDQQN--------ILQVQSLQLQERMMSLLEKIIAKSNV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZTZ1-1", "uniprot_id": "MSD1_HUMAN", "id": "Q6ZTZ1-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "aln": "MVRGAGPGPSLSALSHPTGASGMAAAEG-PGYLVSPQAEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESAPPDWPYYLAIDGILAKVPESCDGKLPDSQPPGPSTSQTEASLSPPAKSTPLYFPYNQCSYE----------GRFEDDRSDSSSSLLSLKFRSEERPVK------KRKVQSCHLQKKQ-----------------------LRLLEAMVEEQRRLSRAVEETCREVRRVLDQQH--------ILQVQSLQLQERMMSLLERIITKSSV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZ34-1", "uniprot_id": "E7EZ34_DANRE", "id": "E7EZ34-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "aln": "----------------------MASEDLCFSYTVPGSNEKHRRARNWTDSEMKALVYIWEEYVTELKKAKRNAKIYETMAKQLYELTGEQRHREEIKMKITNMTFQFRKLKYTANGGSSTPDWPYYKSIERILSKVPDHGHMSPPNLSSSGPSTSQHDPAVPQSAPPSGFLPEYTGSSEE----------RDMNDE-DDGLTDNSASSFETRSQPHK------RRRLSHVSLRRKK-----------------------LRVLDAMLKEQRRISHAVEEACHEVRRVMHQQN--------FLQVQSLQLQERMMNLLEKMIPAQSAPS-WPNPASAKGLGTPTPE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7H8-1", "uniprot_id": "Q9I7H8_DROME", "id": "Q9I7H8-1", "name": "Myb/SANT-like DNA-binding domain-containing protein", "aln": "----------------------------------MPYEKFNKKRRQWEDSGVLELIKLWKVCAYELRTIKRNGHLYVAMAKQLTSLG-VPVTALEVHFKVNNLTQRYRQEQKTFETTGIISTWKFYSQVDDVFKSLAAHTGYKDKRMTSASNTSSLPSTSESPVWKNPMSQQEFNSNNTEGFYKTEYGMHRHFMDHSQPPPNAGSVDNFMASSAAVAAVAAAASARLADNNMDQQMNTAAGGSGGSGGGGGNTNGGVANYQKIKKSHEDYDKFVDIVKNIVDTHKSTPDKVDTFGDFIKSYMKRWPERLQDEAINHITNYVIVKNMEHSMVSSHNPEGVNNRQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: *:* *: : *: :*: **: ***.::* **.:* .: *:::*:.*:* ::*: : : . . * :* :: :: .:. . .. ::* ..: . . :. . * : *. . . .* : . . :: : :: : :. :: :: ::: : . .: . :: . :**:. :. : . : .. ", "identical_positions": 27, "similar_positions": 93, "identity": "7.83%" }, { "cls_id": "homologset.agr.HGNC:33742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1PRL5-1", "uniprot_id": "CAVN4_RAT", "id": "B1PRL5-1", "name": "Caveolae-associated protein 4", "aln": "MEHNGSASNAGKIHQNRLSSVTEDEDQDAALTIVTVLDRVATVVDSVQASQKRIEERHREMGNAIKSVQIDLLKLSQSHSNTGYVVNKLFEKTRKVSAHIKDVKARVEKQQVRVTKVETKQEEIMKKNKFRVVIFQEDVPCPASLSVVKDRSLPENEEE-AEEVFDPPIDLSSDEEYYVEE----SRSARLRKSGKEHIDHIKKAFSKENMQKTRQNFDKKVSGIRTRIVTPERRE--RLRQSGERLR--QSGERLRQSGERFKKSISNATPSKEAFKIRSLRKPKD-PKAEGQEVDRGMGVDIISGSLALGPIHEFHSDGFSETEKEVTKVGYIPQEGGDPPTPEPLKVTFKPQVRVEDDESLLLELKQSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AMM0-1", "uniprot_id": "CAVN4_MOUSE", "id": "A2AMM0-1", "name": "Caveolae-associated protein 4", "aln": "MEHNGSASNAGKIHQNRLSSVTEDEDQDAALTIVTVLDRVASVVDSVQASQKRIEERHREMGNAIKSVQIDLLKLSQSHSNTGYVVNKLFEKTRKVSAHIKDVKARVEKQQVRVTKVETKQEEIMKKNKFRVVIFQEDIPCPASLSVVKDRSLPENQEE-AEEVFDPPIELSSDEEYYVEE----SRSARLRKSGKEHIDHIKKAFSRENMQKTRQTLDKKVSGIRTRIVTPERRE--RLRQSGERLR--QSGERLRQSGERFKKSISSAAPSKEAFKIRSLRKAKD-PKAEGQEVDRGMGVDIISGSLALGPIHEFHSDEFSETEKEVTKGGYSPQEGGDPPTPEPLKVTFKPQVRVEDDESLLLELKQSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BKX8-1", "uniprot_id": "CAVN4_HUMAN", "id": "Q5BKX8-1", "name": "Caveolae-associated protein 4", "aln": "MEHNGSASNADKIHQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVEE----SRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRE--RLRQSGERLR--QSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAARPVYPPHEGREIPTPEPLKVTFKSQVKVEDDESLLLDLKHSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L260-1", "uniprot_id": "CVN4A_DANRE", "id": "A1L260-1", "name": "Caveolae-associated protein 4a", "aln": "MEKRG---------DVILGVEDESGQPVSALSILSLLERVSTIIDGVQASQQRMEERQQQLEGSVSAVQSELLKLARDHGATATTVDKLLQKARRVSTHVKEVRSRVEKQNVRVKKVETTQDELLTRNKFRVVIYQGEKEVPSVAVTKTPKGAGLAELEVEPDEYDIPADLSSDEEYMVVEDAESSRGARLKQSGLKGIENIKAAFSKENMNKTREKTRENLSKTKESLSKTGQTLGTKFNTLGEKIVPPEQREKIKQSSERLKENIAKKAPTKESFKIK-LKKERT--VAEGQEGAEAEPAVTPPKGRKSSP--------------DVTYTEVVTENKREGPVSE------EGATRIHED-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.* : *. *. : :**:*:::*::*::::*.*****:*:***:::: .::.:** :****::.*. *. ::**::*:*:**:*:*:*::*****:::*.***..*:*::.:*******:* . *: . . :. : * : :* * :******* * * **.***::** : *::** ***:***:***:. :::. : : .. : ::. **:: :. *:::**.**:*:.*:. :*:**:**:: *:* : ***:* . . . . .* :.: ..: : *..* : .::.:* ", "identical_positions": 112, "similar_positions": 131, "identity": "30.11%" }, { "cls_id": "homologset.agr.HGNC:33743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLZ3-1", "uniprot_id": "D3ZLZ3_RAT", "id": "D3ZLZ3-1", "name": "", "aln": "--------------------------MKERFTEADTGAKLDDFRKRLLGFIVGIMIIAFTFTCFCLLHYNCMVEEVQSPGGLNKENMAAISSWVSKVSACQPDMITEDILEAQPLLFNSDQLSGPSCQEKHLISNNIVKSIQPSSLEKSCIPS-NVQKTTKYINIEKSSTSCSPKPSNRLLESKRSIKSSDPKRLHKSSHMERTCKKHNIKKSQKITHGYKLGNVNSSCSDKQVTPWLAVLKTSTKQITQSSSSIPCKQSTFTKPCRIRKPNLPYGHYEVKRPANR-GKTLFPKPTAAKTCRHYKERCLVCNTSGFLLNDLSGAEKNHAGNICGSMKMKPCLHTFYDTEYKYNYYQKSVSN-DTMKMYDSEDSNAEIVIICDTSQDDITNKGTFRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAS1-1", "uniprot_id": "E9QAS1_MOUSE", "id": "E9QAS1-1", "name": "", "aln": "------------------------------------------------------MIIAFTFTCFCLLHYNCMVEEVQPPGGLNKENMEAISSWVSKVSEYQPDMIVEDILETQPLLLNVDQTSAPLCPDKQPIPNNTAKSIQASSLEKPCIPSPNAQKSTKCINIEKSSTSCSAKYSNRPLKSNRPTMSSNPKRLCKSSHLEKTYNKCGLKKSNKLNHACKFANFNSSCSDKQATPWLSVLKSSAKQTTQSSSLISHDQITPTKPRRIKKPNLSHGHYEVKRSVNR-RKPLLPMPTTAKVCRHYKDKCLVCNNSGFLLSDLSGEEKNNEEKLYGSMKVKPHHNPFYDTGYKYKTYEKSVSN-DTMKECDSEDSNSEIVLICDISHDNITNK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JRM2-1", "uniprot_id": "CX066_HUMAN", "id": "Q5JRM2-1", "name": "Uncharacterized protein CXorf66", "aln": "MNLVICVLLLSIWKNNCMTTNQTNGSSTTGDKPVESMQTKLNYLRRNLLILVGIIIMVFVFICFCYLHYNCLSDDASKAGMVKKKGIAAKS---SKTSFSEAKTASQCSPETQPMLSTADKSSDSSSPERASAQSSTEKLIRPSSLQKPSIPN-------------------SAGKLTRPSYPKRSSKSSCSKKLSKSSHLEKAHKKGSLEKLCKLDYACKLASSDKPVR-------------PPQLFKPLYSSHPQNEISPSKPFGPQELAKPPKHFNPKRSVSLGRAALLSNSELAETCQPYKKKHLVAKTYRPLVNDISEAKEKNTQNLHVSSKVKSSSRSFRKLDSRNNAYGDHVNDSDTMKYYSEVDSDKVIIITCDRGYNQVTSEVTLND", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:.*.* *** *****: ::.. .* ::*:.: * * **.* :.. : *:**:* . *: * . . :: .. * *:.***:*..**. *. .* .:*. ** .*:* ****:*:: :* .::* *: :. *:.. :.. ..: . * . .: : :** :: . *:: **... .*:. . *:.*: **.: **.:. *:.*:* :::: :: * *:*. ..* . : : * . *.: **** .. **: *:: ** . :::*.: ", "identical_positions": 80, "similar_positions": 118, "identity": "20.2%" }, { "cls_id": "homologset.agr.HGNC:33744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AC18-1", "uniprot_id": "A0A8I6AC18_RAT", "id": "A0A8I6AC18-1", "name": "", "aln": "-MALPWLQRLELVLFTAAFLCGALAAAALTRTQASFGGSCPLYGAVALNGT--YLALSHPSASSLCYFVAGASGILALYCLLLLFFWVYSSCIE-DSQRGSIGLRIALVISAIAIFLILVSACILRFGTNSFCNSIISLNHTIS-CSEAQKISWKPPGTAVQFYSNLHNAETSSWVNLILWCLALMLQVMQCKFQATPYQPQERGDPEWSSETDALVGHRQSHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CY24-1", "uniprot_id": "T179B_MOUSE", "id": "Q9CY24-1", "name": "Transmembrane protein 179B", "aln": "-MALPWLQRVELLLFTAAFLCGALAAATLTRTQGSFGGNCPLYGVAALNGS--SLALLGPSAPSLCYFVAGASGILALYCLLLLFFWVYSSCIE-DSHRGSIGLRIALAISATAIFLILVSACILRFGTNSFCNSIISLNLTIS-CSEAQKTSWTPSGTAVQFYSNLHTAETSSWVNLILWCLALLLQAMQCKFKATSYQPQERGDQEWSSETDALVGHHQSHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7N9-1", "uniprot_id": "T179B_HUMAN", "id": "Q7Z7N9-1", "name": "Transmembrane protein 179B", "aln": "-MALSWLQRVELALFAAAFLCGAVAAAAMTRTQGSFSGRCPLYGVATLNGS--SLALSRPSAPSLCYFVAGASGLLALYCLLLLLFWIYSSCIE-DSHRGAIGLRIALAISAIAVFLVLVSACILRFGTRSLCNSIISLNTTIS-CSEAQKIPWTPPGTALQFYSNLHNAETSSWVNLVLWCVVLVLQVVQWKSEATPYRPLERGDPEWSSETDALVGSRLSHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T392-1", "uniprot_id": "T179B_DANRE", "id": "Q7T392-1", "name": "Transmembrane protein 179B", "aln": "-MALPRPLLLELLLYGSCFICGIITAASVTISQGSFDGKCMLYGSVRLNSS--TIDVLSFSSLSLCYFVSAISVCVAVFCFSLTLYWIYIAFVDGEIKREKLWMNVTLGLSGVFLFFLLVTGCILKIGRDRLCDSLLHTVSNITRCEEAQNKSWRSPINASQFYTRLHSAETAVWVNFFFWMIIVVLVLIQ-RHKGSEIRPGTEDPSAPPSETEPFFNRPGRP-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F498-1", "uniprot_id": "E7F498_DANRE", "id": "E7F498-1", "name": "", "aln": "MMGLPWLLVLELVLYAGCFICGVIAAAWMTLTQGHFDGLCILYGSVHFNTSGQALTVEGSSSPSVCYFVSAIAVCMAIYCFSLILYWIYASCVEEDVRRGTVSLNTSLGVCGLLLFLLLVSGCILKIGRDSLCFSVLHNVPSLNSCEDAENKTWAHPYSGNQFYTGLYSTERSMWVSFFFWILITAVVVIQ-RRQSSSLKVWGDDEWSR-AETEPFLHRPSRQR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*. :** *: ..*:** ::** :* :*. *.* * *** . :* : : : *: *:****:. : :*::*: * ::*:* : :: : :* : :. :* :.. :*::**:.***::* :* *:: .:. *.:*:: .* . .. ***: *:.:* : **.:.:* : : :* : :.: : . :**:.:. ", "identical_positions": 55, "similar_positions": 86, "identity": "24.55%" }, { "cls_id": "homologset.agr.HGNC:33745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IMG9-1", "uniprot_id": "SMIP8_RAT", "id": "Q6IMG9-1", "name": "Sperm microtubule inner protein 8", "aln": "MARIIDLVPWDECSAHLYASPAILIPLERVRRPLAGVKHQLYHPGLPSLRRMDMDSVKGCLSDEHCQSSTYYTKDDFNEAHFTLLGVPNKPLHCLDFTATGQKLCHKYRDGKMIPIVPGIQRADWPCFTRAIEDWSQFVSKSGEFKLPCANRRVEGFSGYAVRYLKPELTQNWRYCLNQNPSLDRYGQKPLPFNTLNSFRRFGSHYSRINYLTPWH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IMH0-1", "uniprot_id": "SMIP8_MOUSE", "id": "Q6IMH0-1", "name": "Sperm microtubule inner protein 8", "aln": "MAQIIDLVPWDECSAHLYASPAVLLPLERVRHPLAGVKHQLYHPALPSLRRMDMDTVKGCLSDEHCQSSTYFSKDDFNKAHFTLLGVPNKPLQCLDFTATGQKLCHKYRGGKMIPIAPGINRVDWPCFTRAIEDWSKFVSRSEEFKLPCANKRVEGFSGYAVRYLKPEVTQNWRYCLNQNPSLDRYGQKPLPFDSLNAFRRFGSHYSRINYLTPWH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6URK8-1", "uniprot_id": "SMIP8_HUMAN", "id": "Q6URK8-1", "name": "Sperm microtubule inner protein 8", "aln": "MARIIDLVPWDDGSTHVYASPAILLPMERQRNQLAGVKQQLYHPALPTLRHMDRDTVKACLPDEHCQSTTYCRKDEFDNAHFTLLGVPNKPLQCLDITATGQKLRNRYHEGKLAPIAPGINRVDWPCFTRAIEDWSHFVSSAGEFKLPCLRKRAEGLSGYAVRYLKPDVTQTWRYCLSQNPSLDRYGQKPLPFDSLNTFRSFGSSYSRVNYLTPWH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:********: *:*:*****:*:*:** *. *****:*****.**:**:** *:**.**.******:** **:*::*************:***:******* ::*: **: **.***:*.*************:*** : ****** .:*.**:**********::**.*****.***************::**:** *** ***:*******", "identical_positions": 160, "similar_positions": 42, "identity": "74.07%" }, { "cls_id": "homologset.agr.HGNC:33747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2T4-1", "uniprot_id": "FIBIN_RAT", "id": "Q5U2T4-1", "name": "Fin bud initiation factor homolog", "aln": "------------------MMFTKLIWMGFFCHLCRGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDRRRCSQGEGGQASSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLGISVGLRDKYELLAHTIRSHGTRLGRLKSDYLEGGGQKMG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQS3-1", "uniprot_id": "FIBIN_MOUSE", "id": "Q9CQS3-1", "name": "Fin bud initiation factor homolog", "aln": "------------------MVFPKLIWMGFFCHLCRGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDRRRCSQGEGGQASSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLDISVGLRDKYELLAHTIRSHGTRLGRLKSDYLEGGAQKTG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAL6-1", "uniprot_id": "FIBIN_HUMAN", "id": "Q8TAL6-1", "name": "Fin bud initiation factor homolog", "aln": "------------------MVFLKFFCMSFFCHLCQGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDHRRCSQGEGSQVGSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLDISVGLRDKYELLALTIRSHGTRLGRLKNDYLKV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1IGX5-1", "uniprot_id": "FIBIN_DANRE", "id": "A1IGX5-1", "name": "Fin bud initiation factor", "aln": "-------------MGTMASPLFILIACLLSMRVGGAFFAGPLYPEMSNGTFHHYFVPDGYYEENDDPEKCQMLFKMMDNRKCTLDEDQDS------VIRDDFTIIKRHIEDAARVLEGIGKSISFDLDGEDSYGKYLRRETTQISEAFSNSEKSLLELEVKFKQSQENELKEEHKISDDFLNMIVHTRDVLKETLDISLGLKDKHELLSLIIRSHGTRLSRLKNDYMKV------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB12ZRE6-1", "uniprot_id": "A0AB12ZRE6_DANRE", "id": "A0AB12ZRE6-1", "name": "", "aln": "MWTSPLSGRSDLRRGQKRSIMLPFALGLFLLPLCGAVYEGPLLPEMSNGTFHHFFVPDGDYEETEDPEKCQMLFKWIDRRPCPLEEDRDT------VIREDFVIVKQQIEDAARVLETLGKSISFDLDGEDSYGKYLKREIEQIGEAFTNVEKSLLELESKFKQSQETEQREESEFSSNFIKPVYDVRETLQETLDISSGLKDKHELISLIVRNHGSRLSRLKNDYLNV------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . : *** *******:**:***** ***.:******:**: *.* *. *. : .:*::*.:: :::***.**** :.****:*****:******:** **.:*::* :*** *** ****.** : ::* .:..:*: : ..*. *:***.** **:**:**:: :*.**:**.***.**:: ", "identical_positions": 99, "similar_positions": 64, "identity": "42.13%" }, { "cls_id": "homologset.agr.HGNC:33748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9Z9-1", "uniprot_id": "D4A9Z9_RAT", "id": "D4A9Z9-1", "name": "", "aln": "MGQKASQHVALRDSQEVLVMCEVVSAAISHAAQKLKEYLGFEYPLSRLCLTASFLAEIFLVHFITFCQERGADEWLTTTKTSKHQALLFGADWIWTFWGPDKQIRLQVAVQALRMASLPPRDPKSC-----ESRGEES-WRKGRFDKLEEFCNLVGEDCLGLFIIFGVPGEPKAIRGVVLETVRNGMVESQLPGRKAVEQFVLETEDCVSIKELLGNCLDKRDGLSDMGKVYVRIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7T1-1", "uniprot_id": "REP15_MOUSE", "id": "Q9D7T1-1", "name": "Rab15 effector protein", "aln": "MGQKASQQVAPKDSQEVLAMCEVVSAAISHAAQKLKEYLGFEYPLSRLCLAASSLTEVFLVHFVTFCQERGADEWLTTTKMTKHQAWLFGADWIWTFWGPDKQIRLQVAVQTLRMASLPLTDPKSC-----ESRGEES-WKKGRFDKLQEFCNLVGEDCLGLFIIFGVPGEPKAIRGVVLESVRNGMMESQLPGRKAVEQFVLETKDCISIKELLGNCLSKRDGLSDMGRVYIRIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6BDI9-1", "uniprot_id": "REP15_HUMAN", "id": "Q6BDI9-1", "name": "Rab15 effector protein", "aln": "MGQKASQQLALKDSKEVPVVCEVVSEAIVHAAQKLKEYLGFEYPPSKLCPAANTLNEIFLIHFITFCQEKGVDEWLTTTKMTKHQAFLFGADWIWTFWGSNKQIKLQLAVQTLQMSSPPPVESKPCDLSNPESRVEESSWKKSRFDKLEEFCNLIGEDCLGLFIIFGMPGKPKDIRGVVLDSVKSQMVRSHLPGGKAVAQFVLETEDCVFIKELLRNCLSKKDGLREVGKVYISIL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******::* :**:** .:***** ** *************** *:** :*. * *:**:**:*****:*.******** :**** ************.:***:**:***:*:*:* * :.*.* *** *** *:*.*****:*****:************:**:** ******::*:. *:.*:*** *** ******:**: ***** ***.*:*** ::*:**: **", "identical_positions": 162, "similar_positions": 46, "identity": "68.64%" }, { "cls_id": "homologset.agr.HGNC:33749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8F1-1", "uniprot_id": "CC184_RAT", "id": "Q4V8F1-1", "name": "Coiled-coil domain-containing protein 184", "aln": "MEDSLLEIMTKDGGDMPAPLEVSTVPAVGDVISGEYNGGMKELMEHLKAQLQALFEDVRAMRGALDEQASHIQVLSDDVCANQRAIVSMCQIMTTAPRQGGLGVAGGKGSFPSVPHEPETPSPGIGDSGLLGRDPDEEDEEEEEEKETASPATPTSHCERSESP--GLLGENGPLVEPLDLPDITLLQLEGEASL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMK5-1", "uniprot_id": "CC184_MOUSE", "id": "Q8BMK5-1", "name": "Coiled-coil domain-containing protein 184", "aln": "MEDSLLEIMTKDGGDMPAPLEVSTVPAVGDVISGEYNGGMKELMEHLKAQLQALFEDVRAMRGALDEQASHIQVLSDDVCANQRAIVSMCQIMTTAPRQGGLGVAGGKGSFPSVPHEPETPSPGIEDSGLLGRDPDED--EDEEEKETPNPATPTSHCELSESP--GLLGEDGPLVEPPDLPDITLLQLEGEASL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q52MB2-1", "uniprot_id": "CC184_HUMAN", "id": "Q52MB2-1", "name": "Coiled-coil domain-containing protein 184", "aln": "MEDGLLEIMTKDGGDMPAPLEVSTVPAVGDVISGEYNGGMKELMEHLKAQLQALFEDVRAMRGALDEQASHIQVLSDDVCANQRAIVSMCQIMTTAPRQGGLGVVGGKGSFQSDPQEPETPSPGIGDSGLLGRDPEDE-EEEEEEKEMPSPATPSSHCERPESPCAGLLGGDGPLVEPLDMPDITLLQLEGEASL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.****************************************************************************************************.****** * *:********* *********::: *:***** ..****:**** .*** **** :****** *:**************", "identical_positions": 171, "similar_positions": 13, "identity": "87.69%" }, { "cls_id": "homologset.agr.HGNC:33751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCH2-1", "uniprot_id": "NHLC3_MOUSE", "id": "Q8CCH2-1", "name": "NHL repeat-containing protein 3", "aln": "--------------------------------------------------MARAWVCLAGAAFFLSCLVLHSRFCGSLVSRTFSFHVSWRMEDPLFRLDLGWPKNSEYFTGATFCVAVDSLNGLVYVAQRGDNIPKVLVFSEDGYFLRAWNYTVDTPHGMFVSGTPFEQSVWITDVGSGPYGHTVKKYNSLGDLVQVLGTPGKKGTGLNPLQFDNPAELYVDDTGEMYIVDGDGGLNNRLVKLSQDFMILWLRGENGTGPAKFNIPHSVTLDAVGRVWVADRGNKRLQVFDKDTGEWLGAWDNCFTEEGPSAVRFTPDGKYLIVAQLNLSRLSVLLAPPSGSIGDCSVVSTIQLADQVLPHLLEVDRKTGAVYVAEIGAKQIQKYIPWHSRTPAFGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2F6-1", "uniprot_id": "D4A2F6_RAT", "id": "D4A2F6-1", "name": "NHL repeat-containing protein 3", "aln": "MYFSERGSHCFSVTVPSLFSFAVLCFDSWMLPLPQTRLQAPLTFTSQALRMARTWVCLAGAVFFLSCLVLHSRFCGSLVSRTFSFHISWRMEDPLFRLDLGWPKNSEYFTGATFCVAVDSLNGLVYVAQRGDDIPKVLVFSEDGYFLRAWNYTVDTPHGMFVSGTPYEQSVWITDVGSGPYGHTVKKYNSLGDLVQVLGTPGKKGTGLNPLQFDNPAELYVDDTGEIYIVDGDGGLNNRLVKLSQDFMILWLRGENGTGPAKFNIPHSVTLDSVGRVWVADRGNKRLQVFDKDTGEWLGAWDNCFTEEGPSAVRFTPDGRYLIVAQLNLSRLSLLAAPPSGSIGDCTVVSTIQLADEVLPHLLEVDRKTGAVYVAEIGAKQIQKYVPWHSRTPALGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JS37-1", "uniprot_id": "NHLC3_HUMAN", "id": "Q5JS37-1", "name": "NHL repeat-containing protein 3", "aln": "--------------------------------------------------MARFWVCVAGAGFFLAFLVLHSRFCGSPVLRNFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSVWITDVGSGFFGHTVKKYSSFGDLVQVLGTPGKKGTSLNPLQFDNPAELYVEDTGDIYIVDGDGGLNNRLIKLSQDFMILWLHGENGTGPAKFNIPHSVTLDSAGRVWVADRGNKRIQVFDKDTGEWLGAWNNCFTEEGPSSVRFTPDGKYLIVAQLNLSRLSVVAAPPVGSIGECSVISTIQLADQVLPHLLEVDRKTGAVYVAEIGAKQVQKYVPLNSYVPSFGS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ***:*** ***: ********** * *.*:* :*** *. *:***:****:.*****:**************:.****:***:***:******************:*.:.* :************ :*******.*:***************.**************:***::*************:***********:*******************:.************:**************:*********:*******:*************:: *** ****:*:*:*******:************************:***:* :* .*::*:", "identical_positions": 284, "similar_positions": 49, "identity": "71.54%" }, { "cls_id": "homologset.agr.HGNC:33752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D4V6-1", "uniprot_id": "TO20L_MOUSE", "id": "Q9D4V6-1", "name": "TOMM20-like protein 1", "aln": "MPSVRLGVGLLAGLAAGGAVVLLSYCVYLDWRRHRDPAFRRRLQDKRRAGQPKAQAPARQLWDPVKKEELQEYFFREVQMG---------------------KLCLIRGERGMGFEHLTNALLVCEQPKELLMFFKKTLPPEVFQMLLDKIPLI--------CQQLEETCRSTEHLKDDPD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JU30-1", "uniprot_id": "A0A0G2JU30_RAT", "id": "A0A0G2JU30-1", "name": "TOMM20-like protein 1", "aln": "MPSVRLSVGLLAALAAGGAVALLCYCVYLDRRRHRDPAFRRCLRDQRRAGQSNAKAPARQLWDPEKKKTLQEFFLQEMQMG---------------------KLCLARGEHGMGFEHFTNALLVCGQPKELLMFFKNTLPPEVFQMLLYKIPII--------CQQLEADMHEQEVLDG-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXN7-1", "uniprot_id": "TO20L_HUMAN", "id": "Q6UXN7-1", "name": "TOMM20-like protein 1", "aln": "MPSVRSLLRLLAAAAACGAFAFLGYCIYLNRKRRGDPAFKRRLRDKRRAEPQKAEEQGTQLWDPTKNKKLQELFLQEVRMG---------------------ELWLSRGEHRMGIQHLGNALLVCEQPRELLKVFKHTLPPKVFEMLLHKIPLI--------CQQFEADMNEQDCLEDDPD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGX9-1", "uniprot_id": "Q9VGX9_DROME", "id": "Q9VGX9-1", "name": "TOMM20-like protein 1", "aln": "MIGVSGTFKVLAAISG---ILFMGYCVYFDKQRRSDPDFKRKLHERRIQRSLASVKSTASVS--MSERDVEVYFMTQIHKG---------------------ETLITNGDVEAGVEHLINAILVCGQPSKLLQLLQSTLPMDIFTTMLIKM------------HAYEASQRCLPVLVDDEATSSL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35180-1", "uniprot_id": "TOM20_YEAST", "id": "P35180-1", "name": "Mitochondrial import receptor subunit TOM20", "aln": "MSQSNPILRGLAITTAIAALSATGYAIYFDYQRRNSPQFRKVLR-QRAKEQAKMEEQAKTHAKEVKLQKVTEFLSMELAKDPIPSDPSEREATFTTNVENGERLSMQQGKELEAASKFYKALTVYPQPADLLGIYQRSIPEAIYEYIILMIAILPPANVASFVKGVVGSKAESDAVAEANDIDD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ** :. . *.:*:: :*: .* *:: *: :* . . : : :: . . : .*. . .:: :*: * ** .** . : ::* :: :: : : : ", "identical_positions": 18, "similar_positions": 44, "identity": "9.73%" }, { "cls_id": "homologset.agr.HGNC:33753", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN13-1", "uniprot_id": "INSY1_RAT", "id": "B0BN13-1", "name": "Inhibitory synaptic factor 1", "aln": "MNIRGAPDLGQPSDDPNSGGERERIRQRMKMVIGQLEGILRELKEVAKELREVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGAGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPSDSVDGPEAPRPGTGPDYQLMNGGLPIPNGPRVETPDSSSEEAFSAGP-AKGQVPQRTPGTRERVRFSDKVLYHALCCDDEEGDGE--EVEEEEAG-LAPELPRVEPHTGPLKPSPAPYKTKRSPLTTRRLGP---TLAPEQTRRVTRNSSTQTVSDKSTQTVLPYTATKQKAKGKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CD60-1", "uniprot_id": "INSY1_MOUSE", "id": "Q8CD60-1", "name": "Inhibitory synaptic factor 1", "aln": "MNIRGAPDLGQPSDDPNSGGERERIRQRMKMVIGQLEGILRELKEVAKELREVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGVGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPSDSVDGPEAPRPGTGPDYQLMNGGLPIPNGPRVETPDSSSEEAFSAGP-AKGQVPQRTPGTRERVRFSDKVLYHALCCDDEEGDGE--EGEEEEEGDLAPELPRVEPHTGPLKPSPAPYKTKRSPLTTRRLGP---TLAPEQTRRVTRNSSTQTVSDKSTQTVLPYTATKQKAKGKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2T9L4-1", "uniprot_id": "INSY1_HUMAN", "id": "Q2T9L4-1", "name": "Inhibitory synaptic factor 1", "aln": "MNIRGAPDLGQPSDDPSSGGERERIRQRMKMVIGQLEGILRELKEVAKELREVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGMGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPSDSVDGPESTRPGAGPDYRLMNGGTPIPNGPRVETPDSSSEEAFGAGPTVKSQLPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEQ-EVEEEEVG-LPPEPAHTEAHAGPHKPSPAPYKSRRSPLTSRHSGS---TLAPEQTRRVTRNSSTQTVSDKSTQTVLPYTATRQKARGKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L899-1", "uniprot_id": "INSY1_DANRE", "id": "Q1L899-1", "name": "Inhibitory synaptic factor 1", "aln": "MSQSRAPAR-EPSETPS---QREQIRSHMKMVIQQLEGILKELKDVAHELREVVGQIDKLTSDLELDLDADDWTVATASSTSSSER----GLCEAFRLDFLGQDSLSDSWDFCSFLESSSRRSARDDTKPP-PTTASVYSQMNGGLPVPNGPLIITPDSSSEEASSSTH-SQSQKTSRTAGTRERVRFSDKILYHALCCDDDEDEDEDEDGRDEEEDKLDTDSERSPLAGSPVPPLPELYNCREPPAGGSHTIPRKDALNPGCRKKLLRNSSTQTVSDKSTQTLLPYVPAKHRNKDL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ** :**: *. :**:**.:***** ******:***:**:******.********::::*:.****.**.******:: * : :***: * *****:*****: *: .: *..:.. * :.. * **** *:**** : ********* .: :.* ..**.***********:*********:*.:.* : .:** . * .: : .* * * *: :..* : . :* * ::: ***************:***..:::: :. ", "identical_positions": 143, "similar_positions": 79, "identity": "47.99%" }, { "cls_id": "homologset.agr.HGNC:33754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A288-1", "uniprot_id": "A0A8I6A288_RAT", "id": "A0A8I6A288-1", "name": "", "aln": "MKGRAQHHGSAHLCVGWWSLVGATPPSERSTALEGVAMGLPWKGRRLLLQPARSPAHAHARLHGRVAAGVRTRCVEQRSQGAASTAAQEGSMSATRAKKVKMATKSCPECDQQIPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRRRTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSSSAKKHEEEREKQEKEIDIYANLSDEKAFVFSVALAEINRKIINQRLIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR55-1", "uniprot_id": "CP087_MOUSE", "id": "Q9CR55-1", "name": "UPF0547 protein C16orf87 homolog", "aln": "-------------------------------------------------------------------------------------------MSATRAKKVKMATKSCPECDQQIPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRRRTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSSSAKKHEEEREKQEKEIDIYANLSDEKAFVFSVALAEINRKIINQRLIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PH81-1", "uniprot_id": "CP087_HUMAN", "id": "Q6PH81-1", "name": "UPF0547 protein C16orf87", "aln": "-------------------------------------------------------------------------------------------MSATRAKKVKMATKSCPECDQQVPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRRRTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSASAKKHEEEREKQEKEIDIYANLSDEKAFVFSVALAEINRKIINQRLIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGQ4-1", "uniprot_id": "CP087_DANRE", "id": "Q6DGQ4-1", "name": "UPF0547 protein C16orf87 homolog", "aln": "-------------------------------------------------------------------------------------------MSTNKVKKVKMATKSCPECDQQIPVACKSCPCGYVFISRKLLNAKLNERS--GVMDKLEDKRRRTERIRKEKINLTSTSDMENRRRSRTNSHSDPIRRGRGRPKTVGLKKQEEEKEKQEREVDIYANLSDEKAFVFSVALAEINRKILGQRLIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.:.****************:***********:********** .*:* .. :* * *******:*:**** * ..*:***:***:***** *********: . **:***:****:*:*************************:.*****", "identical_positions": 117, "similar_positions": 26, "identity": "47.76%" }, { "cls_id": "homologset.agr.HGNC:33755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAQ5-1", "uniprot_id": "CP086_RAT", "id": "D3ZAQ5-1", "name": "Uncharacterized protein C16orf86 homolog", "aln": "MASAGAKRQPEAQNGAAVGLAQVAEIPECPGTEEC-------LVPAHETCSTPGEDRCPVGHSLEPELQEEGINLGEEGLNPGVEAGEERGPKPTSSIVRPAHGPKRK---------------AEAELPPGLLLQKEEPEGSHSESSLSSKQHKKAKKRKSVGAPVPPAVASASAP-TETLGLEPFAVPWVLAGKAQRLRPLYQYINYCNPELNQAGDGDREPEAEPESELALAPEEAGVEQLQLQTLLPMAGELGLGLALPCPNPLAPLTHNLPPLVEEVGEEPGGLSSLRVSGSLKAEVDKTTQVDIDKMLSVCAAPLVPPLSPQYK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4A5-1", "uniprot_id": "CP086_MOUSE", "id": "Q9D4A5-1", "name": "Uncharacterized protein C16orf86 homolog", "aln": "MASEGAKRQPETQNGAAVGLAQVAESLECPGTEEC-------LVPAHETCRSPGEDKCPVGHSLEPELQEEGIKVGEEGLNAGVEAGEERGPKPTSSIVRPAHGPKRK---------------SEVELPPGVLQKKEEPEGSHSESSLSSKQHKKAKKRKSGGAPVPPAVASASAPAAETLGLEPFALPWVLAGKAQRLRPLYQYINYCNPELNQEEDGDREPEVEPEAELALVPEEPGVEQLQLQTLLPVAGELGLGLALPCPNPLVPLTHNLPPLVEEVGEEPGGLSSLRVSGSLKAEVDKTTQVDIDKMLSVCAAPLVPPLSPQYK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZW13-1", "uniprot_id": "CP086_HUMAN", "id": "Q6ZW13-1", "name": "Uncharacterized protein C16orf86", "aln": "MASAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLER---------KAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQ--ALLPLAGELGPGLALPCPSPLVTPTHALAPLGEEAGEEPGGLPSLGVS-DHKAEVDKSTQVDIDKMLSVCTAPLVPPLSPQYK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **:*:* .*:.:.** .*::* .. *.** ******: : .**: *.* : *.****** ::*** :. . * *****:*. ***** ****** :*.**** : ::****.*:**.* *:*********** **** **** :. *** ** ***********:********* .** *.*.*.*:*** .*** ****** :***:***** *******.**.. ** *.** **.*******.** ** . ******:************:************", "identical_positions": 194, "similar_positions": 56, "identity": "58.97%" }, { "cls_id": "homologset.agr.HGNC:33756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1Q7P2-1", "uniprot_id": "A0A8M1Q7P2_DANRE", "id": "A0A8M1Q7P2-1", "name": "", "aln": "-----------MVSGLGRCLAAAALLSFLLFLSSLWLPQGTVQGCEDSWR-----------------------------------PCLSAYKSAKQVDHASIPEELRASDLIRECNGQKFQVSRLLLHLNSALGPASDVLLDPYLLCWEELIKFMEALGPLVGFFTHKVEEKIALIRQLS--LEESTRHSVTASNSMMYGAQHEAP-------PPGHAYHSVHSMLEAELQRGVVSFDQQTPSGSRTLLRLHRSLLWLQLLLEKLGTEREG----RSFGELCREAYLEVLAPHHPWLVQRAAELVFHAMPDRSVFLQLVCVRT-QEEAEPVMRIVVAAIREIHQRTQRELEIRNMLDLP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2CF29-1", "uniprot_id": "A2CF29_DANRE", "id": "A2CF29-1", "name": "", "aln": "-----------MDV---RCRACVVVIFILLLLGSLCLHR-ILEHHSEVY--------------------------------------------SVKIKVVSLVTDNTSDAPLSVCPDQSFQIAYLLAHLQAAPLAANDVLLKPYLASWDELIKFLEALGPIVGIISQEIESKTTIIRDLAQKAEEEEKKMIERKETTKQLAQSKSSNYSKMDQTLSSGYTSVRSMIKMELENGLVDFQTQTNSGCRTLLRLHRALLWLQNFLHELGKDVAKGERLRRPSDLCKETYQRTLARHHSWWARKAAELAFLAMPERSYFYKLVCVKT-QAEASVVLNRVVKAIEKVYKRNEVALQEHDMLDLP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5Y8A9-1", "uniprot_id": "A0A8I5Y8A9_RAT", "id": "A0A8I5Y8A9-1", "name": "", "aln": "MVLGVSLSP-ALGRWFRHAIPFAIFTLLLLYISVWLFHEWPFELPAQRTQQSGLWELKLSSPSPALTSLLPVTSGVLPGCRPGVQSCNPERALPSQIGPALRPLVVPEKEEP-PCLRPHGLLGRMVSPFLACMSPEGDVELSQYLAGWRELLRLLTPLGSVFAFATSEASNKVTALEAHVHGPDASHYTSLVTMATWERRAV-------------------------LLERPGTTPRHLARPSGSQTLLLLHRALRWSQLCLHRVATGKLGG---PEAGAQCRDAYSTALAPYHPWLIRQAARLAILTLPSRSRLLQLACPGTGEADARVALARAARVLEDVYNRTQGLLASHGLLQLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0R6-1", "uniprot_id": "GLTD2_MOUSE", "id": "Q8K0R6-1", "name": "Glycolipid transfer protein domain-containing protein 2", "aln": "MVMGVSLSP-ALGRWFRHAIPFAILTLLLLYISIWFFYEWPFPLPAQRTQQSGLRGLKLPSPSPVLGSLLSFP--------AGVQSCNPERPLPSQTGPAARPLVVPEKEEL-PCLGPHGALGRMVSPFLACMSPEGDVALSQYLAGWRELLRFLTPLGTVFAFATSEAFNKVTDLEARVHGPNASHYTSLMTMITWERGAG-------------------------LLQRPGTEPGHSAGSSGSRTLLLLHRALRWSQLCLHRVATGTLGG---PDAGTQCGEAYSTALAPHHPWLIRQAARLAILALPSRGRLLQLACPGTGEADARVALARAAGVLEDVYNRTQGLLAGHGLLQLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NH11-1", "uniprot_id": "GLTD2_HUMAN", "id": "A6NH11-1", "name": "Glycolipid transfer protein domain-containing protein 2", "aln": "--MGVAARPPALRHWFSHSIPLAIFALLLLYLSVR-------SLGAR----SGCG--------------------------PRAQPCVPGETAPFQVRQESGTLEAPERKQP-PCLGPRGMLGRMMRRFHASLKPEGDVGLSPYLAGWRALVEFLTPLGSVFAFATREAFTKVTDLEARVHGPDAEHYWSLVAMAAWERRAG-------------------------LLEQPGAAPRDPTRSSGSRTLLLLHRALRWSQLCLHRVATGALGG---PDAGVQCSDAYRAALGPHHPWLVRQTARLAFLAFPGRRRLLELACPGATEAEARAALVRAAGTLEDVYNRTQSLLAERGLLQLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MLW4-1", "uniprot_id": "Q8MLW4_DROME", "id": "Q8MLW4-1", "name": "Glycolipid transfer protein domain-containing protein", "aln": "------------------------------------------------------------------------------------------------MSKTSLATQTNGTAEN----GNCFDILKVSNLFETSLLDEDDVQLDAYLAAYEEIMKFFQLMGSVFSFVSSDVRSKIDILYALRAKDAEEQEHFNTFRTMLD------------------------------YEKEAQLLTQKGYVSGSRTLLRLHRGLDFVYEFLNRIQAIPDDQ----KTVDVCKEAYDDTLGKHHSFLIRKGARLAMYAMPTRGDLLKKVCSDVEAAKEN--LPSMLKHMRTNYDRTEDLYTLYDLHSLP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. .** *. ** : ::.:: :*.:..: : . * : . . . . **.:*** ***.* : *..: * ::* .*. :*.: :: *.*.: ::* * : : .* . . : :. :.*.: .: .*.", "identical_positions": 28, "similar_positions": 63, "identity": "7.8%" }, { "cls_id": "homologset.agr.HGNC:33757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BP07-1", "uniprot_id": "TM220_MOUSE", "id": "Q8BP07-1", "name": "Transmembrane protein 220", "aln": "MAPAVATWAPGLWRACNALMAAFFALAAVVQVNDPDAELWVVVYMIPAVLTLLVGFNPLVTGNFIWKSVSAIHMLFCALWAGGLAYHFLLHAKQNLLNEEEGRELSGLVIVTAWMALCHSSSKNPGGGRMHLAIAVVITLLPLLSWVYVHMNKEMRSSWPTHCKTVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2I6-1", "uniprot_id": "D4A2I6_RAT", "id": "D4A2I6-1", "name": "", "aln": "MASAVAPWAPGLWRACNALMAAFFALAAVVQVNDPDAELWVVVYMIPAVLTLLVGFNPLVTGNCIWKSVSAIHMLFCALWAGGLAYHFLLHAKQSILNEEEGRELSGLVIVTAWMALCHSSSKNSVGGRMHLAIAVVITLFPLLSWVYVYMNKEMRSSWPTHCKTVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6QAJ8-1", "uniprot_id": "TM220_HUMAN", "id": "Q6QAJ8-1", "name": "Transmembrane protein 220", "aln": "-------MAPALWRACNGLMAAFFALAALVQVNDPDAEVWVVVYTIPAVLTLLVGLNPEVTGNVIWKSISAIHILFCTVWAVGLASYLLHRTQQNILHEEEGRELSGLVIITAWIILCHSSSKNPVGGRIQLAIAIVITLFPFISWVYIYINKEMRSSWPTHCKTVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FET6-1", "uniprot_id": "E7FET6_DANRE", "id": "E7FET6-1", "name": "", "aln": "MNKNGVSVFQTIWRVCNLFMSVFFSLATYVQINDPDAALWMVGYAIPAVLCFLIFCQQQITESLLWRRIADLHVLVASTFGVILAWKLYKEGITDIFQQEEGRECCGLLLTVFWLLLCRHSGRSSTIGSVRIFTAVGISVFPFVTWLYYYMNKELRKHWPEHCTTAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**.** :*:.**:**: **:***** :*:* * ***** :*: : :* . :*: :: :*:*..: :. ** : . .::::***** .**:: . *: **: *.:.. * ::: *: *:::*:::*:* ::***:*. ** **.*.:", "identical_positions": 57, "similar_positions": 61, "identity": "34.13%" }, { "cls_id": "homologset.agr.HGNC:33758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8L9-1", "uniprot_id": "D4A8L9_RAT", "id": "D4A8L9-1", "name": "BTB/POZ domain-containing protein 17", "aln": "---------------MIRKGSCKPGSWGSFWAILALVGLATRAVGSTRLGAF-SGSAMSLPAAAQRADVVGEAAGISINHSHMLLQRLQDLLRHGNASDVVLRVQAVGTDEVRAFHTHRLLLGLHSELFRELLS--NQSEVVLQEPGDCAAVFDKFIRYLYCGELTVLLAQAIPLHRLATKYRVASLQRGVADYMRAHLAGG--AGPAVGWYHYAVSTGDEALRESCLQFLAWNLSAVAGSAEWGAVSPELLAQLLQRSDLVLQDELELFHALEAWLGRTRPPPTVAERALRAIRYPMIPPAQLFQLQARSAALARHGPAVADLLLQAYQFHAASPLHYAKFFHVNSSAFLPRNYLAPAWGAPWVINNPARDDRSTSFQTQLGPSGHDAGRRITWNVLFSPRWLPVSLRPVYADAAGTALPAARPEDG----RPRLVVTPASSGGDAAGVSFQKTVLVGARHQGRLLVRHAYSFHQSSEEAGDFLAHADLQRRNSEYLVENALHLHLIVKPVYHTLIRTPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB72-1", "uniprot_id": "BTBDH_MOUSE", "id": "Q9DB72-1", "name": "BTB/POZ domain-containing protein 17", "aln": "---------------MLRKGSCKPGSWGSFWAILALVGLVTR--------------------AAQRADVGGEAAGTAINHSHMLLQRLQDLLRQGNASDVILRVQAVGTDEVRAFHTHRLLLGLHSELFRELLS--NQSEVMLRESRDCAAVFDKFIRYLYCGELTVLLAQAIPLHRLATKYRVASLQRGVADYMRAHLAGG--VGPAVGWYHYAVSTGDEALRESCLQFLAWNLSAVAGSAEWGAVSPELLAQLLQRSDLVLQDELELFHALEAWLGRARPPPTVAERALRAIRYPMIPPAQLFQLQARSAALARHGPAVADLLLQAYQFHAASPLHYAKFFHVNGSAFLPRNYLAPAWGAPWVINNPARDDRSTSFQTQLGPSGHDAGRRITWNVLFSPRWLPVSLRPVYADAAGTALPAARPEDG----RPRLVVTPASSGGDAAGVSFQKTVLVGARHQGRLLVRHAYSFHQSSEEAGDFLAHADLQRRNSEYLVENALHLHLIVKPVYHTLIRTPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NE02-1", "uniprot_id": "BTBDH_HUMAN", "id": "A6NE02-1", "name": "BTB/POZ domain-containing protein 17", "aln": "---------------MPRRGYSKPGSWGSFWAMLTLVGLVTH--------------------AAQRADVGGEAAGTSINHSQAVLQRLQELLRQGNASDVVLRVQAAGTDEVRVFHAHRLLLGLHSELFLELLS--NQSEAVLQEPQDCAAVFDKFIRYLYCGELTVLLTQAIPLHRLATKYGVSSLQRGVADYMRAHLAGG--AGPAVGWYHYAVGTGDEALRESCLQFLAWNLSAVAASTEWGAVSPELLWQLLQRSDLVLQDELELFHALEAWLGRARPPPAVAERALRAIRYPMIPPAQLFQLQARSAALARHGPAVADLLLQAYQFHAASPLHYAKFFDVNGSAFLPRNYLAPAWGAPWVINNPARDDRSTSFQTQLGPSGHDAGRRVTWNVLFSPRWLPVSLRPVYADAAGTALPAARPEDG----RPRLVVTPASSGGDAAGVSFQKTVLVGARQQGRLLVRHAYSFHQSSEEAGDFLAHADLQRRNSEYLVENALHLHLIVKPVYHTLIRTPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E4N9-1", "uniprot_id": "A0AB40E4N9_DANRE", "id": "A0AB40E4N9-1", "name": "", "aln": "MLSYVPASYIKSVGQAAHTDRETRVGEKKHIERNKDNMVKSGGRSVPVVVCLASLCLALCAGAALKPDVLLDNTATTLNHSMALVQRMEALLTQGNGSDVVLRVQTVNTDEVKVIQVHSLVLTLQSDVFDELLQTRNSTAMVLKETSDCAAVFEKFVRYLYCGDITVRLNQAIPLHKLATKYHVWDLQQGLTQYMTQHLSSDSPAGHVVAWYQYATQIGDVTLQNSCLQYLSWNLSSVLQSAEWSSVSGELLLSLLQRSDLVLQSELELYEALEAWINQNQPSDETAENALKAIRYAMISPQNLFHLQKKSPLMLKYYESVRDLLFLAFQFHAASPIQLAKYYDVNCSLFTPRNYLSLSWGSPWVINNPTRDDRSFSFQTQLGPSGHDVSKRITWNALFSPRWLPLSVRSSYPEQG--SMLLTRTDAG----RPRIIVTPATSSPDFAGVSFQKTVIVSARKQGKVVVRHVYNFHQSTEEAGDFLLEADLQRRASEYLIDSSLYLHIIVKPLYHTLIVSKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K2-1", "uniprot_id": "A0ACD6B7K2_DANRE", "id": "A0ACD6B7K2-1", "name": "", "aln": "---------------MARVRRNELVFVYLFFS-----MLVAG-----------SLLRPVRGG--LRAEGLVEGSAEVISHSQGLVARLEGLLLLGNNSDISLRVETVDADEVKVIQAHTLVLSMQSRVFEEMLRKRNSSTLVLQETAECTAVFDKFIRYLYCGELSLQLDQATPLHSLATKYAISGLQQGLTQYMSQNLASDSPTGHVVGWYQYATKVGDMTLKNNCLQFLSWNLSSVLQSPEWPLVSIELLMTLLQRSDLVLKNELELFEAVETWLTQNNPDSLTAENALRLVRYAMIPPRELFRLQRQSPIMTRYHESVRDLLYMSYQFHSASPLQLAKFFDMNCSLFVPRNYLSSMWGAQWIINNPARDDRSTSFQTQLGPSGFDSSKRVTWNALFSPRWLPLSMRPMYTEQG--AMQPPRPDGGSGIARPRIIITPATSSADFAGVNFQKTVLVLTRQKGKLVVRHILGFHQSTEEVGDFLADADLQLRTSEYVVDGSLYLHIIVKPIYQTLITTKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : :.: : :. :.** :: *:: ** ** **: ***::..:***:.::.* *:* ::* :* *:* *.: :*:*. :*:***:**:******:::: * ** *** ***** : .**:*:::** :*:.. .* .*.**:**. ** :*::.***:*:****:* *.** ** *** *********:.****:.*:*:*: : .* .**.**: :**.**.* :**:** :*. : :: :* *** ::***:***:: **::.:* * * *****: **: *:****:***** **********.* .:*:***.********:*:*. *.: . :: .*.: * ***:::***:*. * ***.*****:* :*::*:::*** .****:**.**** .**** * ***:::.:*:**:****:*:*** : .", "identical_positions": 222, "similar_positions": 148, "identity": "42.61%" }, { "cls_id": "homologset.agr.HGNC:33760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3Z9-1", "uniprot_id": "M0R3Z9_RAT", "id": "M0R3Z9-1", "name": "Keratin-associated protein", "aln": "MANRNNCSSS--CTSGSLRNSCHIPASSNIALCSTNMGCGEVFCVPSNCQDHTWFMDNCPETFAEPISGQPPSREASGFENSCCSS-AYCVPRPCHGSGYLPTTSFISGSCLPASYRPVSYVSSSCRPVSPFMNSCRPVS-CGSGGYRPLPCVSNSCRPVGIVTYGCRPSGCVTYGPQTIHIVSNSLRPLQPVCGGCQPAIPVFGSCRPSCSAQGGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7N2-1", "uniprot_id": "KR261_MOUSE", "id": "Q9D7N2-1", "name": "Keratin-associated protein 26-1", "aln": "MASRNNCSSSGNCSSGSLRNTCHIPASSSIALCSTNMGCGEVFCVPSSCQDHTWFMDNCPETFAEPLSGQPPSREASGFENSCCSS-TYCVPRHCQGSGYIPASSFISGSCLPASYRPVSYVSSSCRPVSPFMNNCRPVS-CVSGGYRPLPCGSNSCRPLGIVTYGCRPSGCVTYGPQTIHIVSNSLRPLQPVCGGCQPSIPVFGTCRPSCSAQGGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PEX3-1", "uniprot_id": "KR261_HUMAN", "id": "Q6PEX3-1", "name": "Keratin-associated protein 26-1", "aln": "MSCPNYCSGN--SNSGSLRTSRHIPLTS-IDLCPTSVSCGDVLYLPTSSQDHTWVTDNCQETCGEPTSCQPVHCETGNLETSCGSSTAYYVPRPCQGSSFLPAS-FFSSSCLPVSCRPQRYVSSGCRPLRPLLNSYQPIGDCVPNAYRPQFCLSKSCQPQNLLTSGCQPSSCLAYRPQSLHVVSSSLRPLGPLFSGCQPLTHVFSTCRPSCSGL---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * **.. ..*****.: *** :* * **.*.:.**:*: :*:..*****. *** ** .** * ** *:..:*.** ** :* *** *:**.::*:: *:*.****.* ** ****.***: *::*. :*:. * ...*** * *:**:* .::* **:**.*::* **::*:**.***** *: .**** **.:******. ", "identical_positions": 108, "similar_positions": 64, "identity": "49.77%" }, { "cls_id": "homologset.agr.HGNC:33762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47940-1", "uniprot_id": "RES18_RAT", "id": "P47940-1", "name": "Regulated endocrine-specific protein 18", "aln": "------------------------------------------MQSSLKPAGSGVLQLLVCFLLLYSRPSSCSDINAHDGQGQVGSEQLWTFQGLVASVFQYLQLLFHHIVPQGMFWTDDIAYELMTKKVEHLSRLHPQYPCRKEGKVVSPIATTGVRGKQEEKLRLLSPQKSPAVKVNRDRCFTTKVIPKATKQEVTHPSKGFF-------------GP------FPTVGLNLVAD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47939-1", "uniprot_id": "RES18_MOUSE", "id": "P47939-1", "name": "Regulated endocrine-specific protein 18", "aln": "------------------------------------------MQSSLKPAGSGHLQLLVCFLLLYSRPGSCSDINAHDGQGQVGSEQLWTFQGLIASVFQYLQLIFHQIVPEGMFWADDIAYELMTKKVEHLSRLHPQYPCRKDMKAVSPTANAGVRSKQEEKLQLLSPQKSPTVKVNRDRCFTTKVIPKATKQEATHPTKGFF-------------GP------FPTVGLNLVAD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5W5W9-2", "uniprot_id": "RES18_HUMAN", "id": "Q5W5W9-2", "name": "Regulated endocrine-specific protein 18", "aln": "MAVDVEFGVAGWWEAAAPLSPSAVAATFTETWPGSERAEPGRIQHPLWPGSSEGLQLLVCFLLLNSCPGGCSDTSAHDGQDQVGVGQLWPLQGFATPVFQHLQVVLQQIIPQGLFWKDDITQDAMIQKMEHASRLHPQEPCLKDGKALFPTKTT----------------ESPLAKVNRDQCFTSEVVSKALKQEVANPVKITYRCSYGGLDMMQAPGPSKEEIIYKIMRLLWATSYCGPQPCG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* *..* ********** * *..*** .*****.*** ***.:**: :.***:**:::::*:*:*:** ***: : * :*:** ****** ** *: *.: * .: :** .*****:***::*:.** ***.::* * : ** : : * .:. ", "identical_positions": 81, "similar_positions": 47, "identity": "33.2%" }, { "cls_id": "homologset.agr.HGNC:33763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CXL7-1", "uniprot_id": "SNORC_MOUSE", "id": "Q9CXL7-1", "name": "Protein SNORC", "aln": "MASCLALRVALLLISGVLAPAVLT-AEGPQEPDPTLWNEPIELPSGEGPLESTSHNQEFAVSGPPFPTSAPAPEDSTPPARVDQDGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LSS7-1", "uniprot_id": "A0ABK0LSS7_RAT", "id": "A0ABK0LSS7-1", "name": "Secondary ossification center-associated regulator of chondrocyte maturation", "aln": "---MIAIGSPYGFCVGLCAPGLLSFPEGPQEPNPTLWNDPIELSSGEGPLESTSHKQEFAVSGPPFPTSAPAPEDSTPPARVDQDGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UX34-1", "uniprot_id": "SNORC_HUMAN", "id": "Q6UX34-1", "name": "Protein SNORC", "aln": "MASCLALRMALLLVSGVLAPAVLT-DDVPQEPVPTLWNEPAELPSGEGPVESTSPGREPVDTGPPAPTVAPGPEDSTAQERLDQGGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: . : *: **.:*: : **** *****:* **.*****:**** :* . :*** ** **.*****. *:**.*************************************", "identical_positions": 79, "similar_positions": 19, "identity": "64.75%" }, { "cls_id": "homologset.agr.HGNC:33764", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GIN6-1", "uniprot_id": "A0A8I6GIN6_RAT", "id": "A0A8I6GIN6-1", "name": "", "aln": "MLHLRPRSPSADPASCWSPQASAPSPAKRRRLHQEPARPEPLAQPELEEPA-GTASSALTSVVFLAAGCALQLPLDGVDLLLEPEPTSALQVSLQGHTILLVPEGLLTEPQPEQPGFVATSPQGAAPQDMP----QDHLLGFQ-QEAFCEYFYQEGVCDEDADMDILGSWASPPAGQATGSLSSITGVLSPWSQGGVPEPCLLVPSTGAEQYYQSSIEELDSYLLGPCPGSPLQPLPASPL-SSQEQRSPRPPRSPRPPCKARKRLFYD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A3M0-1", "uniprot_id": "A0A8I6A3M0_RAT", "id": "A0A8I6A3M0-1", "name": "", "aln": "MLRLRPRSPSADPASCWSPQASAPSPAKRRRLHQEPARPEPLAQPELEEPA-GTASSALTSVVFLAAGCALQLPLDGVDLLLEPEPTSALQVSLQGHTILLVPEGLLTEPQPEQPGFVATSPQGAAPQDMP----QDHLLGFQ-QEAFCEYFYQEGVCDEDADMDILGSWASPPAGQATGSLSSITGVLSPWSQGGVPEPCLLVPSTGAEQYYQSSIEELDSYLLGPCPGSPLQPLPASPL-SSQEQRSPRPPRSPRPPCKARKRLFYD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZMC7-1", "uniprot_id": "A0A8I5ZMC7_RAT", "id": "A0A8I5ZMC7-1", "name": "", "aln": "MLRLRPRSPSADPASCWSPQASAPSPAKRRRLHQEPARPEPLAQPELEEPA-RPASSALTSVVFLAAGCALQLPLDGVDLLLEPEPTSVLQVSLQGHTILLVPKELQASTHFGQPGFVATSPQGAAPQDMS----QDHLAGLQ-QESLCEYFYQEGVCDEDADLDFLEPWAKLPAGQAPGSLSSITGVPSSWSQDRVPEPCPLVPSTGAEQYLQRSIEELDSYLLGPFPGSPLQPLPAFLR-SPQEQRSPRPSCSPRPPCKARKRLIYD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YWX5-1", "uniprot_id": "D3YWX5_MOUSE", "id": "D3YWX5-1", "name": "", "aln": "MLRTRPRSPCVDPAPCWSPQTSAPSPAKRRRLHQEPACPEPLAQPELEAPA-EPT----TSVVFLAAGSALQLPLDGIDLLLEPEPTSVLQVSLQGHTILLVPEGLMTQPQPGQPGFVAISPQGAAAQDGP----QDHLVGLQ-EET-CEYFYQEDVCNEDADLEFLEPWARPPDDQANGSFFSIPGVPSPLLQEQVPG-----PSTGAERYSPRSIWELDSYLLGPLPGSPLQPLPPSPSQSPQEQLPPCPPCSPRAPCKARKRLVYD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3UW32-1", "uniprot_id": "G3UW32_MOUSE", "id": "G3UW32-1", "name": "", "aln": "MLRTRPRSPSANPAPCWSPQTPAPSPAKRRRLHQEPACPEPLAQPELEAPA-EPASSALTSVVFLAAGSALQLPLDGIDLLLEPEPTSVLQVSLQEHTILLVPEGLMTQPQPGQPGFVAISPQGAAAQDGP----QDHLVGLQ-EETFCEYFYQEDVCDEDADLELLEPWARPPDDQANGNFSSIPGVPSPLLQEQVPG-----PSTGAERYSPRFIWELDSYLLGPLPGSPLQPLPPSPSQSPQEQLPPRPPCSPRAPCKARKRLVYD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CWP9-1", "uniprot_id": "P23A3_MOUSE", "id": "Q9CWP9-1", "name": "Proline-rich protein 23A3", "aln": "MLRTRPRSPSADPAPCWSPQTPAPSPAKRRRLHQEPACPEPLAQPELEAPA-EPT----TSVVFLAAGSALQLPLDGVDLLLEPEPTSVLQVSLQGHTILLVPEGLQDSTHFGQPGFVAISPQGAAAQDGP----QDHLVGLQ-EETFCEYFYQEDVCDEDADLEFLEHWASPPDDQANGNFSSIPGVPSPLSQDQVPG-----PSTGAEQYSPRFIWELDINMLGPFPGSPLQPLPPSPSRNPQEQLPPCPPCSPRAPRRARKRLVYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZRT6-1", "uniprot_id": "PR23B_HUMAN", "id": "Q6ZRT6-1", "name": "Proline-rich protein 23B", "aln": "-MVSRPRSPSAFPAPWWGQQPGGPGPAKRLRL-EEPAGPEPRAAPSLEDPAGDPAVDALTSIVVLAAGCALRVPLDDVDLVLEPAPTSILRVSLGGHTLILIPEVLLSSVD-ERSGAQHDSSAGLEVDVFLGAVREDVVVELEFCASVPEIAAQEEAYEEDADPEFPELRMDSPTGSAAGLYPSSRSMFIPYREGPIPEPCALAPNPSSERRSPRPIFDLEFRLLEPVPSSPLQPLPPSPCVGSPGP-HARSPLPERPPCKARRRLFQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *****.. **. *. *. .*.**** ** :*** *** * *.** ** .: **:*.****.**::***.:**:*** *** *:*** **::*:*: * . . :.* *. * : :* : :: : * ** . :**** :: * ..* * * .: . : :* *...:*: * :*: :* * *.*******. .. . .. . *.* :**:**. ", "identical_positions": 93, "similar_positions": 67, "identity": "34.57%" }, { "cls_id": "homologset.agr.HGNC:33765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A518-1", "uniprot_id": "A0A8I6A518_RAT", "id": "A0A8I6A518-1", "name": "", "aln": "MDRHIPMHALPKEIQQMSPEETVCKYCGVSYLILHEFKAMEEKLKAVQEELKFYQGSIEREKRLQEKLQSLSQEFEKYKTDSESKKERVQHASMQLKKQQNEFQRVQKELSHLQLELKIKQKQSQVFSQRLSEYKYFWNKTLLLLTFTKRELTSIKYEINDNFQNWTSLKGEVFLQIKSISDTALAEIDMLNKSLTVSQRNKVSLEEEMKCLKVLSDAAILRSQQMEASKQHEVNLQARCYELQKEALDLQCQVEALGLRLQKTVKELDNCKEMLMKKSNDANNCERELRKLKFESIISESRHKRLLKEKEDSLITCQQLYKTVQEELTTKGRQEEDIKRRINLAENELEMTKTLLLQTQEEILTLKNERELMLVSHQKSIEQLQETLRQKLLSDDSWREKIEAELSKERARHRIEFQDQALLFKEEAKLELDIEKEKHQEIIRKYQKEQEGLQSKIADLIADATKDLRLEVASLQEKLHESHARYTEESESKKKEIEDLKNLVAELECRLKEETGHDDSVSKELKKEMKQKSDELERVRLAQTQLLQQFSQSQEENTFLQETVRRECEERFELTEALSQAKEQLLELKRSGGSLRCSLNKGALTHPVSAVSNHRELSNVRHNCGRGTSSASLRGLPKPTATPTPDKLKKVDSSGLPALSQAYPPRGRAISVTEARQRLTAIIRRRLSQQR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A571BF98-1", "uniprot_id": "A0A571BF98_MOUSE", "id": "A0A571BF98-1", "name": "", "aln": "MDRHIPMHALPEEIQKMSPEETVCKYCGVSYLILHEFKAMEEKLKAVQEEMKFYQGSVEREKKLQEKLQSLSQEFEQYKSDSESKKARVEDASIQLKKQQNGFQRVQKELGHLQLELKIKQKQSQVFSQRLSEYKYFWNKTLLLLTFTKRELTSIKYEIYDNFQNWTSLKGEVFLQIKSISDTALAEIDMLNKSLTVSQRNKVCLEEEMKSLKLLSDAAILRSQQMEASKQHEVNLQARCYELQKEALDLQCQVEALGLRLQKTAKELDNCKEMLMKKSNDAESCERELRKLKFESIISESRHKRLLKEKEDSLITCQQLYKTVQEELTTKERQEEDIKRRINLTENELEMTKSLLLQTQEEILTLKNERELMLVSHQKSIEQLQETLRQKLLSDDSWREKIEAELSKERARHLIEFQDQALLFKEEAKLELDIEKEKHQEIIRKYQQEHEDLQRKIGDLIADATKDLRLEVASLQEKLHESHAQYTEESESKKKEIEDLKNLVAEFQCRLKQETGRDDSISEELKKEMKQKSDELERVRLAQTQLLQQFSQSQEENTFLQETVRRECEERFELTEALSQAKEQLLELRRSGGNLPCSLNKGTLTYPASAVSNHRELSSGRQNCGRGTGTPSLRGLPKPTASPTPDKLKKVSSSGLPALSQAYPPRGRAISVNEARQRLTAILRRRLSQQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMV7-1", "uniprot_id": "LEKR1_HUMAN", "id": "Q6ZMV7-1", "name": "Protein LEKR1", "aln": "MDHHIPMHALPEEIQKMLPEEKVCKYCGVSYLILHEFKAMEEKVKAMEKEMKFYQGSVDREKRLQEKLHSLSQELEQYKIDNKSKTERIYDVGMQLKSQQNEFQKVKKQLSHLQDELKIKYRQSYIFRLCFC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:********:***:* ***.*********************:**:::*:******::***:*****:*****:*:** *.:**. *: ...:***.*** **:*:*:*.*** ***** :** :* :. ", "identical_positions": 89, "similar_positions": 32, "identity": "12.88%" }, { "cls_id": "homologset.agr.HGNC:33766", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LXM2-1", "uniprot_id": "F1LXM2_RAT", "id": "F1LXM2-1", "name": "", "aln": "MEPTAQRRTEKSFSYVIRAPSIDGSDGINVDVKIDTCWVFRDVEERDKEQGCLPETASS-LDLDTGLLREQLESSERKLLAAVDKHVISESGLRNRVRELELSERRLLLKVEQLRACVAQERSATLHTQEQLQALQGTLVSQVREAESSIR---RQRWLQERLQRKDEALARQAAALKRCGRVQRQQLGLVREQERVLRVQVQRLERDVRRLGRAAGLLLAQLHAADSSPGTRSSGSQFLAGSLGDTEVIELSALRARAELAERERAKAVRRLREHSATERQLREQLEELRCCVYGLTLSEIGLHSQVEELAHQNRRLRAQLG------HSSPGALGCAQSDSLPPLQAVVLDPCSSHSCHG-----DACGLQGLAGQLSEEPPSCVGDGPDHHMTVSTR---TMGKLQRDLSGSEHRQAALVQPHPDLQAPWLLCGCPPGSGMDEPLCSLSLAGLSENLQTVGAQEALLLLPTSMFQLWGPAGDPELLLPPLLQECPLQELQTLEELDRMSSPAHGAFAHPGCHCNLARSHDTSLSQESSHISNDSFLTKGPEEPRDTLQGGHGPPVTSAEKWGVMGTLGGIKSELDDRCLLLLQGSEKLSLDTEVHSLEGMQEGGWAADTQAVASFPWLHSECLTLPLRGTNSRSQEGPDSLSKSRSVEGCGWECLVNLSPEKEEEAIN---FGDHETQEPWTNGSQLPVGKGKEAWRSAQGKLGHQLCFGDTELLPK---ERSGDEEQEEIQIGVTSDPASVG-PEQPEFKTRVGEEQRVLIDDQDLLQFPRLAS--AGTSSEGPCSSQALITGQDRCALQTDTLEKEAEACFQQLNNPKLVCGDAQRTSALVR-QSQRATQRWR-VIEEGVCLQQSLASQDLN----AKSNRNSEGVGPKEDVVLCNGEDLPGAALDGDKANWGPAELGGSQLSPT-WCTLNRAGSRFHQLLANMKKERSQVLLDNARLEGDQEGCRHEGCPCEKEHTGEVAKALRLEQANHVLQGELVRLRHELDQCMQAMSDLEECNRKSYCKISQLEEENEKLKGDLGQLHKAVSESVRKAGSRVKHVTQENTELRALISELGGSYKGLIKDTVLGIEDMVWALQGENEHLVGRVQSLEREV-LQMSRDLGKEKWYSQGNSNMAE-DKGHTKDKEVQVTMFSRQLSTRAGGPSWSEKSNVTG---GPSLDLEGSRCRADTSKTSSVCAVT--TGPQEAHTNGAGGDGAWLQKEQKIPWCSVQEGHPQKSRSHSPQPPNSKVVASEEDTKLCIQRLHHQVRTLQCQLRDQGWALRELQAAQDEATGLQDKLKSKLEELWEQQREVRLASSPLKAKMASLVRKCQERNRLIEHLLQELPRHEPKNHLLSELAQNMLEDVALAEYSATFLTPEASETSCHLDVSSKETSARGGVQEYLFDSEADSVLQNLWGVESWCLPGAEWALQTSP---------------------------GSPKERRQ-----HHQAHHAGKDECPSQVTNGAEVAL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A338P719-1", "uniprot_id": "A0A338P719_MOUSE", "id": "A0A338P719-1", "name": "", "aln": "MEPTAQGQTEKSFSYVIRAPSIDGSDGINVDVKIDTCWVFRDMEESDKEQGRLPETASS-LDLDTGLLREQLESSEQKLLAAVDKHMVSESGLRSRVQELELSERRLLLKVEQLSACVAEERSATIRVQEQLQALKGTLVSQVREAESAVR---RQRRLQERLRRKDEALARQAAALKRCGRVQRQQLGLVREQERVLRVQVQRLERDVRRLGHAAGLLLAQLQAADSSPIMGSSGPQFLAGPLGDPEGEELSALRARAELAERERVKAVLRLREHSATERQLREQLEELRCCVYGLTLSEIGLHSQVEELAHQNRRLRAQLG------HGSPGALGCAQSDSPPPPRAEVLDPGSSHGCHG-----DARELQGPAGQFSEESPSCVGDGPDPHMMVLAR---TIGKLQRDLPGSEHRQGALIQPHLDAQVLRLLCSCPPGSGMDEPLCSLGLSEVSENLQSVGAQEPLLLLPTSMLQLWGPAGDPELLLLPLLQECPLQELQTQEELDSMLSPALGALAHSSCHRNLARNHDITFGRESPLISNGSSLTKGPKEPRDKWQEGSGPPVTSAEKWGVMGTLGGVKSELDDRCLLFLQDSEKLSLDTEVHTPESMQGGGGAADTQAVSSFPWLGSECLILPLHGTASRSQEGPDSLSKRGNVEGCGWERLINLSPE-EEEATS---FRAHGTRT-RTNGSQLSLGKGKDIWRSAQGKQGHQLCFGDAEFLQK---ERSGDGEQEKMQVRVASDSASVG-PEQPEFKTRVGQEQ--CIDDQDFLQLSRWAS--AGASSEGPFSSQALITGQDRRALQTDTLEKEVGAGFQQLNNLQSVCGDPQQMSALMR-ESHSATHRWRRDMEEGVCLQQALASQDLN----AKPNKNDEGVGLDEDVVLCNGEVFPGAVLNGDKANWGSSELGGSQLPAT-CYILNKAGSRFHQLLANTEKERSQILLDNAGLQGHQEGCHHEGCPCEKEHAREAAKALRLEQANHTLQGELVRLRHELDGCLQAVSDLEECNRKSYCKISQLEEENEKLKRDLGQLHKAVAESVRKAGSRVKHVTLENAELRALISELGVSYKGLIKDTVLGIEDMVWALQGENKRLVGRVQGLEREV-LQMSRDSGEETWYSQGNASMVG-DKGHAEDKEVQVTMFSRQLSTRACGPSWAEKSDVAG---GPSLDLEDSKCRADATMTSSVCAAT--TGPQEAHTNGAAGDRAWLPKEQKTPWCSVQQGAPQRSRSLSPQLQNSKAAASEEDTRLCIQRLQHQVRTLQCQLRDQGWALRELQMARDEAVGLQDKLKSKLEELREQQHEVRLASSPLKAKLASLVHKCQERNRLIEHLLQELPRHEPRNRLLSELAQNMLEDIALAEYSATFLTPGAPEMFCHLDVSSKETLA-GGAQESLFNSETDSVLQSLWGAESWSHPGVEWALQTAPP--------------------------GSPKERRH-----HHQAHHDGKDECLSQMTNGAEVAL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZRC1-1", "uniprot_id": "CD050_HUMAN", "id": "Q6ZRC1-1", "name": "Uncharacterized protein C4orf50", "aln": "MEPTAKGRTEESFSYVIRAPSSEGFDIMNVDVKIDTSWIFQDMEDSAEERECLQEEAAGRPDMDMGALRRQLESSEQKLSAAEDKYVTSESGLRSRIQELELSERKLLRKVDQLSTHVAQERSAWLQAQEKLAALQGELASQIREESVARRQQWRLRRLQERLRRKDEALGQQAAALERCRRTQRRQLGLVREQERVLREQVQRLERNVRRLCRAAGLLLAQWDTAAP----GSQG--------ATEAAAELRALQARAERSEREREEAARSLQEHRATERQLRGQLEELRCCIYGLKLSEIGLQGQVEDLAQQNQCLREELGAQAPIGHCSLDALGCVQGDSLPLPREEALDPCRSQDWRNSLRSNDAPRQRAPAGQSPEGPCTWSRIRPGRASSVLAPGPETTSELPRDLAGSNREQLTLAEPSLDEQILLLVCGCPPEECLDESLLRMDLAWISENLAADPAAEAFLLVQTSALPLWGPAGDSASWRPLLLQEVPSDGQKIQEELATRSPPPPKATGHPGWDCHQTRGRGASLFHEAPYISNHPFLKKHPKDLKDTWNNGGGSLAGRTEEGKARGTLGRKGKNLGDKYQLSQESHQNLSLENGAGAAEDVQDQNGASETKAATCRPGSWQEFLMPLLQGEASVSKEGPESLSRRERVEGYVWGLRGGLSSENEEVAPPATFSRAHETKEPWPTDSQLLAGKVRATGRTARGKEENQVWLGNALLLQGGSLEDKGLEEEDEMPHQEASGLGCRGAPEEPDSQEHESKEMLFFAGETGLPLFPRFALSVEGAEPTDHGHPQAVSKGHNRCALTIDELAQDVEACFQQLSTLQPGSRGWQCSASACRGENWSFAQKWHSGWER-AHSQQVWGNWGICSNEEAKSKESGEGDKPGKTTALGTSEVPG---NPGTLPHWDEASPNPPQGPAEPWGALERVRSRFHQLISGLKKQRSQILHDNTKLHGDQERFHERVCALEREREREVTKISRLERDNHRLVGDISQLKKELDQYLQAISDLEDCNGKSYCKILELEEENETLKGNLGQLQKATSESVRKSKDTMEQVTLENWKLQTLISELGVSYKELIKDIVLGIEDMIRALSGENEHLLRRVHVLEREVTLQRSTDQGR---LVRGREHLQGKAKMHALDKEVQVTPLTGQLLSRACGPPLEEEMSLAAGQTGPSTGTGNSRRGADSPPPSLVWRNTGVANALQGNVSGAEVKEAHLEKEEKRPRCSVAQGQALSSLSNGPMLRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAH---QASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDVALAEYTATFLAPGVPETSHHLDVKS-EMTAALRAQTYLLNPEMDSVLQSSLSSESWPIPEPEWPAQTAQLDSLKLPLSLVSTLDPGTCLAAVTVEPGLPAQRLQEKGGMPCPALQVDNVPAPSELLSPARILAFHQELRQSICSNSQVHKSPLELEM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****: :**:********** :* * :********.*:*:*:*: :*: * * *:. *:* * **.******:** ** **:: ******.*::*******:** **:** : **:**** ::.**:* **:* *.**:** . : * * * *****:******.:*****:** *.**:************* *******:**** :******** .:* . *.* . ** **:**** :**** :*. *:** ******* ********:***.******:.***:**:**: ** :** * * .****.*.** * : .*** *:. :. ** :. *** .* . : *. * : * .:* ***.**::.* :* :* * * *:*.*** . :**.* :.*: :**** : * *.:**: ** : *******. **** * : : *** .*. * .*.. . : :*.:. :: :*:. *** . *.* *:: :*. : * *. . :*: . **** .:*.*: * :. ::***:. . : *.:* . *::*:*.:. * .* * *:* * *:***:***: *** * .**.* ** * * *: ...*** ** : *:*:** :*: :*:: :* * .* *:::: :*. .. * **:*: : : .:* .: .: :.* * *:.. . .**: .*::* ** * * ::. * ****.. : . . * :: * :. :::*: *. . ** .. .: **.:...** : ..* ..* * .:*. :. . .* .. *::. ******::. :*:***:* **: *.*.** :.. *. *:*: *.:* ***: ** * *:: :*::*** :**:****:** ****** :******.** :****:**.:*****: . :::** ** :*::****** *** **** *******: **.***::*: **: ***** ** * * *. :*. : * *: ******* :: ** :** **. *: .::. *** . .*: **:. .* * * :.. :.:..** . * * **:* * *** :* . * * .* :*:. .:***.:* *:*:*:* ********** * * : ***. **::*::***** ::*:*.:** :*****:****:**:****** ****** ** * **********:*:*****:****:* ..* ****.* * * .* *::.* *****. . *** * **. **: * * :* : * : .: . *:: . *.: ", "identical_positions": 638, "similar_positions": 375, "identity": "41.67%" }, { "cls_id": "homologset.agr.HGNC:33767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAL1-1", "uniprot_id": "D4AAL1_RAT", "id": "D4AAL1-1", "name": "", "aln": "MASEKDAEKDAEKDAVPALPKLNN-NQTAENTTKPVKDQPRLLRGDDIHLPRFSLKQGMIPTRYVMPWKENMKFRSVNLKQAEACGIYAGPLEDSLFWGYSERLCHGEDRKAVLKKGPPEIKIADMPLHSPLSRYQSTVISHGFRRRLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9I1-1", "uniprot_id": "SMI10_MOUSE", "id": "Q9D9I1-1", "name": "Sperm-associated microtubule inner protein 10", "aln": "MASEKDDG--------PALPKLDDDNQTAENTCKPAEEQPQQLRWDDIHLPRFSLKQGMIPTRYVMPWKENMKFRNVNLQQAEACGIYAGPLEDSLFWGYSERLCHGEDRKAVLKKGLPEIKITDMPLHSPLSRYQSTVISHGFRRRLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNM6-1", "uniprot_id": "SMI10_HUMAN", "id": "Q6ZNM6-1", "name": "Sperm-associated microtubule inner protein 10", "aln": "MASGKDTC--------PTLPKLTN-NCSDESLYKSAN------KYEEIHLPRFSLKQGMIPRRYVMPWKENMIFRNVNLKQAEVCGIHTGPLEDSLFLNHSERLCHGEDRKVVFQKGPPEIKIADMPLHSPLSRYQSTVISHGFRRRLV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** *:**** : * : *. *..: : ::************** ********** **.***:***.***::******** .:***********.*::** *****:************************:", "identical_positions": 99, "similar_positions": 22, "identity": "66.44%" }, { "cls_id": "homologset.agr.HGNC:33768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIS7-1", "uniprot_id": "D3ZIS7_RAT", "id": "D3ZIS7-1", "name": "", "aln": "MAVSVLRLMVVLGLSALILTCWADDNPNDNDHLDEKSDKPDDSKNPEPGFPKFLSILGSEIIENAVDFILRSMSRGSSFMELEGDPGQQPSKVTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V2D2-1", "uniprot_id": "CE046_MOUSE", "id": "Q3V2D2-1", "name": "Uncharacterized protein C5orf46 homolog", "aln": "MAVSVLRLMVVLGLSALILTCRADDNPNENDNPDSKPD--DSSKNPEPGFPKFLSILGSEIIENAVDFILRSMSRGSSFMELEGDPGQQPSKVTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWT4-1", "uniprot_id": "CE046_HUMAN", "id": "Q6UWT4-1", "name": "Uncharacterized protein C5orf46", "aln": "MAVSVLRLTVVLGLLVLFLTCYADDKP---DKPDDKPD--DSGKDPKPDFPKFLSLLGTEIIENAVEFILRSMSRSTGFMEFDDNEGKHSSK---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** ***** .*:*** ***:* *: *.*.* *..*:*:*.******:**:*******:********.:.***::.: *::.** ", "identical_positions": 58, "similar_positions": 24, "identity": "61.05%" }, { "cls_id": "homologset.agr.HGNC:33769", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKQ1-1", "uniprot_id": "A0A8I6GKQ1_RAT", "id": "A0A8I6GKQ1-1", "name": "", "aln": "------MGQHLLRQDSPTETPRGPRKPSGNKRARSLDRQVLRK-DPESSNSRHLSSTTCRR------TASDRARGSESPSHFAEAQGPAAAATARPLGEGNKFLPSEQGPPEDTKKERPPREAQHSWLRAVFDLLLMR-LEEPREKASKMSKGKGNLP------EAAEEPALKKKSQE-KRAVRKKYSHRKPIAEEPPEPQTAEAKGQEDIPPSVAASLATEETDLGLICRGGPESDLPQALPAEGGHAETPGSSGQAAGPPPEEDPRKPDQDDVIWQIVELLKKAGDLLEEEVRRRHQRAPAELLQLRQVPQPEVIPPQKPTPPPRKKSLEKKSSLKR--ALSLKKTTSEEPKRVGLATILGPETRP-KRPSFLPLCVSGPRTSTSRSYDSEAPTVHEVRSVRGGGSHPSELHPPPAVFQGPEEKPLLDRASESREFRRKILALLQSAEEE--QQQVQVKEAEEAGEHPAPAGKVKSQAKKSNLRRAFSLRKHGSKESKRTEASGTPGSGNLEARPPKRHGFLPMCVGGHRASIPSS--PESLEFQKAEAAGGGPAGSPEVPFQARSHIPDEGPPPEGAWESKELIIQKLVASLQEVDRELGRQIRKYPSFRRFFNEFSDASLRKLVATLDRQKALLAEEDRSLGNRPPPPCAFGALNKFATNHSCAICTLMQSRGQYRGHSYAHFLSRKAQQDIMSLDGQSPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CC96-1", "uniprot_id": "BNIP5_MOUSE", "id": "Q8CC96-1", "name": "Protein BNIP5", "aln": "MPRSRNPSQGMPRDSSDSCGLSPVETPKGKKRARSLDRQVPRKKDPESSNTRCPSSATCRR------TASDGARSSESPSHFAEAQG--ATAAALPPGEGRGFLPSEQGPPEDTKKERLPREAQQSWLRLVLNILLMR-IEEPREKASRASKGKGDLP------EAAEEPALRKKSHE-KRTSRKKHSHRKPIAEEPPGPQTAEAQGREDVPPSLAASSAPHEIALGLICRGGPDSDLPQALPTEGDHAETPDSFGQASGPPLEEDPRKPDQDDVIWQIVELLKKAGDQLEEEQ--------------VQIPQPEAVPPRKPTPLPRKKSQEKKSSLKR--VLSLKKPASEEPKRVGTATTLGPETRP-KRPSFLPLCVSSQRASTSSSLDLEAPEFQEVPSVDGGGSHPSELHTPAAIFQGPEEKPLLDRASESREFRRKILVLLQSAEDERGEQEAQAQEAEKAGENPTPAGKVKSQVKKSNLRRAFSLRKHSSKDSKKTEASGTPGSGSLEARPPKKHGFLPMCVSGHRASISSS--PESLEFQKTEAAGGAPAGSPGAPFQARSHTPDEGPSPERAWESKEFMIQKLVASLQEVDRDLGRQIRKYPSFKRFFNEFSDASLRKLVATLERQKASLSEEGRSLANRPPP-CAFGTLNKFAATRSCTICTLMQSRGEYKGHSYAHFLSRKAEQDITNLDSQSPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C671-1", "uniprot_id": "BNIP5_HUMAN", "id": "P0C671-1", "name": "Protein BNIP5", "aln": "-----------------MENPRCPRRPLAEKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALHWTTSDWARHSDSPAPSAEAHC--TTAAAPTPEETGDFLPSEQRPSQDTKKG---------WLKTMLNFFVRTGPEEPREKASRRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQDQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDH-QSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEEEQ--------------SLASQLGVALPN-PAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKR-GAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSES-QEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRR---AGAAGAASPEARRPKRPSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACESKEIIIQKLVALLQEVDGQLGQQIRRHPSFKRFFYEFSDSSLSKLVATLRSQVAHSSKLDRNRARRLYQ-FDVSLANKFAGSNSHAMCILMGLRDHYN---CTQFPYREDQPNITSPKVESPD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .:*:****** ..** : : * .*. *:** ** *:**: ***: ::*:* . * ****** *.:**** **: :::::: ********: .:** .:. *** ****:**::. *:. *** .*:* ** . .* **:*:*: .. **: . * ** *** :** *:: : . : : . :*:* **: :***** :* ******:.** *** .* . *. *:* **** ***:**** . ** ***.** * * .**: * *:.********. *.* * * . * * .:*. *. .*.. ** * .*. * * *: ****** :** :**: :**.**:: ::: *.:: * . *:*:* : *** *:*.:**** :** **:.:: :*:.*:.. *** **: .***:**.***.* .** **.** ::. .* * *. . .* ***.* *: .* . * ****::****** ***** :**:***::***:*** ****:** ****** * * :: .*. ..* .. **** ..* ::* ** *..*. ::* *: : :* . . :***", "identical_positions": 278, "similar_positions": 169, "identity": "39.43%" }, { "cls_id": "homologset.agr.HGNC:3377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LHG8-1", "uniprot_id": "A0ABK0LHG8_RAT", "id": "A0ABK0LHG8-1", "name": "Protein 4.1", "aln": "MSHFCSLLPCAAVTMAALSLPAWLCDNNVYLWNIMTTEKSLAAEAENSQHQ--KEEGEGATNSGQQESQLEEASQAAAAEGSNQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQVSEEEGREVESEREKGEGEQKETELGTSLDEDVILKAPIAAPEPELKTDPSLDLHSLSSIETQPAQEEHREDPDSETKEGEGIEECSGTEVKED-PESRAEREPETSQKPIRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAVWDSTTSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTVQSELGDYDPELHG-VDYVSDFKLAPNQTRELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTLPKS-KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS--KRASRSLDGAAAAES----------TDRSPRPTSAPAIAQSQVMEG-------PGAPAKKAPKEAVKVEEKRGEEPAEP-EPEPTEAWK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKRERLDGENIYIRHSNLMLEDLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSQEEIKKHHASISELKKN-------------------------------------------------------------------------------------------------------------------------------------------------------FMESVPEPRPSEWDKRLSTHSPFR-----------------------------------------------------------------------------TLNINGQVPTGDGSVNGIRTEEVASVTQGPSAYPASERECPKQSVVPSESLMTTPPESPQSFGSGSLSKNSKEAKETEEKEQGAGGHLGAEERPTGPRGECLGVEEQASALSFPVTP-------------------------------------------ASRQLHLGGEKADSSEEPGAPAETPETQSGSFLDSPVGNQFPILTRSFQPPLVKTQTVTISDTANAVKSEIPTKDVPIVHTETKTITYEAAQTEDSN----------------------------------------------GDLDPGVLLTAQTITSETTSSTTTTQITKTVKG---GISETRIEKRIVITGDAD-IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48193-1", "uniprot_id": "EPB41_MOUSE", "id": "P48193-1", "name": "Protein 4.1", "aln": "----------------------------------MTTEKSLAAEAENSQHQQQKEEGEGATNSGQQETQLEEASQAAAAEGSDQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQVSEEEGREVESEKEKGEGGQKEIELGNSLDEDIILKAPIAAPEPELKTDPSLDLHSLSSIETQPAQEEHREDPDSETKEGEGIEECSGTEVKED-PESRAEREPEASQKPVRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLALWDSATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHG-MDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKS-KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS--KRASRSLDGAAAAES----------TDRSPRPTSAPAIAQSQVTEG-------PGAPIKKTPKEAVKVEEKRGEEPAEPAEPEPTEAWKVEKTHTEVTVPTSNGDQTQKLAGKGEDLIRMR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKKRERLDGENIYIRHSNLMLEDLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSQEEIKKHHASISELKKN-------------------------------------------------------------------------------------------------------------------------------------------------------FMESVPEPRPSEWDKRLSTHSPFR-----------------------------------------------------------------------------TLNINGQVPTGDG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPLVKTQTVTISDTANAVKSEIPTKDVPIVHTETKTITYEAAQTEDSN----------------------------------------------GDLDPGVLLTAQTITSETTSSTTTTQITKTVKG---GISETRIEKRIVITGDAD-IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11171-1", "uniprot_id": "EPB41_HUMAN", "id": "P11171-1", "name": "Protein 4.1", "aln": "----------------------------------MTTEKSLVTEAENSQHQQ-KEEGEEAINSGQQEPQQEESCQTAAE-GDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHG-VDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKS-KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS--KRASRSLDGAAAVDS----------ADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQKLAEKTEDLIRMR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKKRERLDGENIYIRHSNLMLEDLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSQEEIKKHHASISELKKN-------------------------------------------------------------------------------------------------------------------------------------------------------FMESVPEPRPSEWDKRLSTHSPFR-----------------------------------------------------------------------------TLNINGQIPTGEG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNS----------------------------------------------GDLDPGVLLTAQTITSETPSSTTTTQITKTVKG---GISETRIEKRIVITGDAD-IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V8R9-1", "uniprot_id": "EPB41_DROME", "id": "Q9V8R9-1", "name": "Protein 4.1 homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPAEIKPSAPAEPETP----------------------------TKSKPKSSSSSHGKPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAES--TNTPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKSSTLDHRGDRNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAVDAAAVPLSDSQKRSYSPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGAAGAAAAAAKPKKRRVKIMVITSKFDPSTKRIDAENGSIEHSTGILDPATGLIDTKYGVIDPKKGTLEALNTKTGKKEVFQGDVDGKTGNLHLVSGVADPKTGRLDDTLGQIVCITPQDNPVVELTVITSRIDPATGKIDTVNGDVERSLGVLNLDTGLLDTKYGEINTRTGELKAIDPKSGKIVVSKNVKVDPGTGQITILGIVDPKTNKIDPNQGRLIEVGQQIDPIVEVTSLAGKFDSKRNIIDPKTAQVETSGGQFDPKAGKIDTKYGQIDLVKHTITFNDPKSGKTVTRDIKIEPTTGQIVLKNQVNPKNNKPDKDYARIISLRIVQQRVDPATKAPITEVSASKDKDIVVDPKSNQIWVPTGATDPATKEQQYISSSVDPKTGYVITIYGYLDPKTNEIKKQTKLDPNTIKIEPTSGKIYTATGEVDQATGEPLYAATQVDPESGEVYTKLARVDPKTGKIVIVRILLISKTDERGRPEEIDPSTCEIDPVSGRVLKFFNKTVYVYNMIDPVTGEIVQVDPNDPRFAGARTTVTHTMTLTGEIDPVTGRIKSEYGDIDPNTGDIDPATAVTDPVTGKLILNYAQIDPSHFGKQAQVQTTTETVPITRQQFFDGVKHISKGALRRDSEGSSDDDMTAQYGADQVNEILIGSPAGQAGGKLGKPVSTPTVVKTTTKQVLTKNIDGVTHNVEEEVRNLGTGEVTYSTQEHKADATPTDLSGAYVTATAVTTRTATTHEDLGKNAKTEQLEEKTVATTRTHDPNKQQQRVVTQEVKTTATVTSGDQYQRRDSVSSTSSGDSGTPIDGPYDGASVVRTDNQKSPLFTTSATTGPHVESTRVVLGEDTPGFSGHGEIISTQTVSSKTRTVETITYKTERDGIVETRVEQKITIQSDGDPIDHDKALAEAIQEATAMNPDMTVEKIEIQQQTQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :*: * * : :..... : : .:*:***.:: : ::::* *:*::: :* ***:*:*****: : .:**** * :.* .* .* :** ******:*:**.******:****:*:**: *****:*.* ****** :***:****.* *:.***:***** ***:***:***:::. :**:*:*.:*******:******* *** *****:****:******:********.***:******* *:******* *:*********..:******** ********** :.:.:.** * .:**.:**.*****:: :.: :**..*:*:** * : :***:*. * .:. .*. * :.. * ::. : : * ** : * *. :: : :. :* * . :*:*.** *.**. :*: .* :: ** ::.: *.. : : :*...* .:*: .* *:.:.*:: . * ** :.* :. .* :..: *::* . * *. *: :: ... *: **. .: *:::* **.* * * * * ** ***:*::*.* .*.* ****:.*.:**:**. :***:* *: ::*:*: ", "identical_positions": 282, "similar_positions": 202, "identity": "14.7%" }, { "cls_id": "homologset.agr.HGNC:33772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD29-1", "uniprot_id": "D4AD29_RAT", "id": "D4AD29-1", "name": "Ragulator complex protein LAMTOR4", "aln": "MTSALTQGLERIPDQLGYLVLSE-GAVLASSGDLENDEQAASAISELVSTACGFRLHHGTNIPFKRLSVVFGEHTLLVTVSGQRVFVVKRQNRGREPIDV---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF66-1", "uniprot_id": "LTOR4_MOUSE", "id": "Q8CF66-1", "name": "Ragulator complex protein LAMTOR4", "aln": "MTSALTQGLERIPDQLGYLVLSE-GAVLASSGDLENDEQAASAISELVSTACGFQLHHGTNIPFKRLSVVFGEHTLLVTVSGQRVFVVKRQNRGREPIDV---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0VGL1-1", "uniprot_id": "LTOR4_HUMAN", "id": "Q0VGL1-1", "name": "Ragulator complex protein LAMTOR4", "aln": "MTSALTQGLERIPDQLGYLVLSE-GAVLASSGDLENDEQAASAISELVSTACGFRLHRGMNVPFKRLSVVFGEHTLLVTVSGQRVFVVKRQNRGREPIDV---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P3X8-1", "uniprot_id": "LTOR4_DANRE", "id": "Q0P3X8-1", "name": "Ragulator complex protein LAMTOR4", "aln": "MTTALTQGLERIPDQLGYLVISE-DGVLASAGELENDEHTAGVIMQMVRTACRFRLHGTAEPPFKRMSVMFEDYVYAVTISGQKVFVVKRQNNQREPVIV---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZL6-1", "uniprot_id": "LTOR4_DROME", "id": "Q9VZL6-1", "name": "Ragulator complex protein LAMTOR4 homolog", "aln": "-MLKMDREKLIVPNQIGYLILKEDGAVLESGGDLKNDERSANVIMGLLNLTETIDESFMPSSSCERITIDYEHHYYSICMSNRRIYIIKISKSQNGVTTTTSSSSSNSVYNDASDSGAVLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:*:***::.* ..** *.*:*:***::*..* :: : : . . :*::: : .: : :*.::::::* .: . . ", "identical_positions": 19, "similar_positions": 43, "identity": "15.7%" }, { "cls_id": "homologset.agr.HGNC:33773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9K6-1", "uniprot_id": "D3Z9K6_RAT", "id": "D3Z9K6-1", "name": "", "aln": "MPWKVLTILLVLSSAQATA-CRWSRAALFPAAHRPKRSLSLPLNPVLQTSLEEVELLYELLLAEIEISPDLKISIKDEELASLRKALNFHSICNNIIPKSIPDIRRLSANLANNPGVLKKEDFERIALTLAYTAYRTALSEGHQKDIWAQSLISLFQALRHDLMRSSSPGVPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BR21-1", "uniprot_id": "F180A_MOUSE", "id": "Q8BR21-1", "name": "Protein FAM180A", "aln": "MSWKALTILLVFSSTQATASCRWSRAALFPAAHRPKRSLSLPLNPVLQTSLEEVELLYELLLAEIEISPDLEISIKDEELASLRKALSFHSICNNIIPKRIPDIRRLSANLANHPGILKKEDFERITLTLAYTAYRTALSEGHQKDIWAQSLISLFQALRHDLMRSSSPAVSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWF9-1", "uniprot_id": "F180A_HUMAN", "id": "Q6UWF9-1", "name": "Protein FAM180A", "aln": "MHWKMLLLLLLYYNAEASMCHRWSRAVLFPAAHRPKRSSSLPLNPVLQTSLEEVELLYEFLLAELEISPDLQISIKDEELASLRKASDFRTVCNNVIPKSIPDIRRLSASLSSHPGILKKEDFERTVLTLAYTAYRTALSHGHQKDIWAQSLVSLFQALRHDLMRSSQPGVPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** * :**: .::*: *****.*********** ********************:****:******:************** .*:::***:*** *********.*:.:**:******** .*************.***********:**************.*.*..", "identical_positions": 134, "similar_positions": 27, "identity": "77.46%" }, { "cls_id": "homologset.agr.HGNC:33775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9C8-1", "uniprot_id": "M0R9C8_RAT", "id": "M0R9C8-1", "name": "", "aln": "MWLAKLSTRVLLLLLLALALSPPGTQ-------------------G-RPRGRRAARVT--ELLPQLFLPVTGTRLAPR--TSRSTEIFPRDLTLKDKFIKHFTG-PVTFSAECSKHFHRLYHNTRDCSMPAYYKRCARLLTRLAVSPLCSQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "J3QPP8-1", "uniprot_id": "ALKL1_MOUSE", "id": "J3QPP8-1", "name": "ALK and LTK ligand 1", "aln": "MWLTKPSTPVSALLLLALALSPPGTQ-------------------G-RPQRSLAARVA--ELRPELFLPVTGTRLPPR--ASRSTEIFPRDLTLKDKFIKHFTG-PVTFSAECSKHFHRLYHNTRDCSTPAYYKRCARLLTRLAVSPLCSQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXT8-1", "uniprot_id": "ALKL1_HUMAN", "id": "Q6UXT8-1", "name": "ALK and LTK ligand 1", "aln": "MRPLKPGAPLPALFLLALALSPHGAH-------------------G-RPRGRRGARVTDKEPKPLLFLPAAGAGRTPS--GSRSAEIFPRDSNLKDKFIKHFTG-PVTFSPECSKHFHRLYYNTRECSTPAYYKRCARLLTRLAVSPLCSQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W2C9-1", "uniprot_id": "ALKL1_DANRE", "id": "F8W2C9-1", "name": "ALK and LTK ligand 1", "aln": "MRAEKRWHILLSMILLLITSSQCMDSKEVKESERKTLLNLILQVIGEKPASRRVTSGLYSVSQDAKFSSRENTAHLPKPDNSRPIEIVPRDTSMKDKFIEHFTAGPVKFPSECRTHFHRIYHNTRDCSRPTYYKRCARLLTRLAMSPLCTQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : ::** :: * * :* : * . .: * **. **.*** .:*****:***. **.*..** .****:*:***:** *:*************:****:*:", "identical_positions": 58, "similar_positions": 27, "identity": "38.16%" }, { "cls_id": "homologset.agr.HGNC:33776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQR2-1", "uniprot_id": "CFA77_HUMAN", "id": "Q6ZQR2-1", "name": "Cilia- and flagella-associated protein 77", "aln": "MPEARSSGPDLTRWRKQQQPVRRTVSQVCPPPRRPLTVADIRSGMENERLGVVRDSMFQNPLIVKAAGPASVGTSYSVYDSSAVQKVIPSLAGHHIKGGPQAELGKPRERSYSLPGINFNYGLYIRGLDGGVPEAIGRWNVFKQQPTCPHELTRNYIAMNRGAVKAGLVTARENLLYRQLNDIRISDQD-DRRMKKEPPPLPPNMTFGIRARPSTPFFDLLQHRYLQLWVQEQKATQKAIKLEKKQKVVLGKLYETRSSQLRKYKPPVKLDTLWHMPHFQKVGRHLDTFPTEADRQRALKAHREECAVRQGTLRMGNYTHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WRI3-1", "uniprot_id": "CFA77_MOUSE", "id": "A0A087WRI3-1", "name": "Cilia- and flagella-associated protein 77", "aln": "MPDPAKPGKDLTAWKKKKQPVHRTVSQICPPPRRPLTVVDIRTGMENERLGVVRDSMFQNPLIVK------------------------------------AELGKPRERSCSLPGINFNYGLYIRGLDGGVPEAIGHWNVFKQQPTCPHELTRNYIAMNRGAVKAGLVTARENMLYRELNDIRINDQE-DRRQK-EPPPIPPNMTFGIRSRPSTPFFDLLQHRYQQLWVQEQKATQQAIKMEKKQKVILGKLYETRSSQLRKYKPPVKLDALWHMPHFKKVASHLATFPTEADRQRALKAHKEEYAVRQGTLRMGNYTHP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BFC9-1", "uniprot_id": "CFA77_DANRE", "id": "A2BFC9-1", "name": "Cilia- and flagella-associated protein 77", "aln": "--------------------------------------------MESPRIGVVRDSMLHRPLLIK------------------------------------PTLGKSKSRGLSYPGPEFVFGTATTVQDGGVQEAISNWHTHTMS-TTHRAAERDFIALNREGVKSGLVTAKELHQYRATHDIRRKPLTREGFRRSAPPRLSPDDSFFVSNRPSTPISELIEYKYAQRWLEEQQVRDRVLQAHQHKKAQLGRIQDTRTTLLRKSQPLPEAPSTWKLPRFQKVGAALDTFRDPEARKKAMNAHCSESVSRRGILGQGTYTVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. *:*******::.**::* . ***.:.*. * ** :* :* **** ***..*:... . * : *::**:** .**:*****:* ** :*** . : : ** :.*: :* : *****: :*::::* * *::**:. ::.:: .:::*. **:: :**:: *** :* : : *::*:*:**. * ** *::*::** .* . *:* * *.** ", "identical_positions": 92, "similar_positions": 78, "identity": "28.66%" }, { "cls_id": "homologset.agr.HGNC:33778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQN5-1", "uniprot_id": "D3ZQN5_RAT", "id": "D3ZQN5-1", "name": "", "aln": "MGTVVAKLLLPTLSSLAFLPTVSIATKRRFYMEAMIYLFTMFFVAFSHACDGPGLSVLCFMRRDILEYFSIYGTALSMWVSLMALADFDEPQRSTFTMFGVLTIAVRTYHDHWGYGVYSGPIGTATLIIAVKWLKKMKEKKGLYPDKSIYTQQIGPGLCFGALALMLRFFFEEWDYTYVHSFYHCALAMSFVLLLPKVNKKAGNAGDPAKLTFSTLCCTCV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1N4-1", "uniprot_id": "MYMK_MOUSE", "id": "Q9D1N4-1", "name": "Protein myomaker", "aln": "MGTVVAKLLLPTLSSLAFLPTVSIATKRRFYMEAMVYLFTMFFVAFSHACDGPGLSVLCFMRRDILEYFSIYGTALSMWVSLMALADFDEPQRSTFTMLGVLTIAVRTFHDRWGYGVYSGPIGTATLIIAVKWLKKMKEKKGLYPDKSIYTQQIGPGLCFGALALMLRFFFEEWDYTYVHSFYHCALAMSFVLLLPKVNKKAGNAGAPAKLTFSTLCCTCV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NI61-1", "uniprot_id": "MYMK_HUMAN", "id": "A6NI61-1", "name": "Protein myomaker", "aln": "MGTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCFMRHDILEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSGPIGTAILIIAAKWLQKMKEKKGLYPDKSVYTQQIGPGLCFGALALMLRFFFEDWDYTYVHSFYHCALAMSFVLLLPKVNKKAGSPGTPAKLDCSTLCCACV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQ69-1", "uniprot_id": "MYMK_DANRE", "id": "Q6IQ69-1", "name": "Protein myomaker", "aln": "MGAFIAKMLLPTISSLVFVPAASVAAKRGFHMEAMVYFFTMFFTAIYHACDGPGLSILCFMKYDILEYFSVYGTAISMWVTLLALGDFDEPKRSSLTMFGVLTAAVRIYQDRLGYGIYSGPIGTAVFMITVKWLQKMKEKKGLYPDKSVYTQQVGPGCCFGALALMLRFYFEEWDYAYVHSFYHVSLAMSFILLLPKKNRYAGTGRNAAKLNCYTLCC-CV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.:**:****:***.*:*:.*:*:** *:****:*:**:**.*: ***:*****:****: *******:****:****:*:**.*****:**::.*:**** *** ::*: ***:******** ::*:.***:*************:****:*** ***********:**:***:******* :*****:***** *: **. .*** **** **", "identical_positions": 154, "similar_positions": 49, "identity": "69.68%" }, { "cls_id": "homologset.agr.HGNC:3378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTP0-1", "uniprot_id": "E41L1_RAT", "id": "Q9WTP0-1", "name": "Band 4.1-like protein 1", "aln": "MTTETGPDSEVKKAQEETPQQPEAAAAVTTPVTPAGHSHPETNSNEKHLTQQDTRPAEQSLDMEEKDYCEADGLSERTTPSKAQKSPQKIAKKFKSATCRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDHDTEEHVG-NYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKG--FLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG--------------------------AEFSRPASVSENHDAGPDGDKREDDAESGGRRSEAEEGEVR-----TPTKIKELKPE-------------QETTPRHKQE------------------------------FLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDR-----------------------------------------------------------DWERERRLP---------------------------------------------------------------------------------------------------------------------------------------------SSPASPSPKG------------------------TPEKAS-------------------------------------------------------------------------ERAGLREGSEEK-------------------------------------------------------------------------------------------------------------------------------------------------VKPPRPRAP------ESDTGD-----------------------------------------------------------------------EDQDQERDAVFLKDNHLAIERKCSSITVSS-------------TSSLEAEVDFTVIGDYHGGAFEDFSRSLPELDR----------------------------------------------------------------------------------------------------------------DKSDSET--------EGLVFARDL-KGPSSQEDESGGIEDSP---------------------------------------------------------------------------------------------------DRGACSTP----ELPQFESVKAETMTVSSLAIRKKIEPEAMLQSRVSTADST-QVDGGAPAAKDFMTTPPCITTET------------ISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYG------------------------------------------------------------ATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDED-VDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2H5-1", "uniprot_id": "E41L1_MOUSE", "id": "Q9Z2H5-1", "name": "Band 4.1-like protein 1", "aln": "MTTETGPDSEVKKAQEETPQQPEAAAAVTTPVTPAGHSHPETNSNEKHLTQQDTRPAEQSLDMDDKDYSEADGLSERTTPSKAQKSPQKIAKKFKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVG-NYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKG--FLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG--------------------------AEFSRPASVSENHDAGPEGDKREDDAESGGRRSEAEEGEVR-----TPTKIKELKPE-------------QETTPRHKQE------------------------------FLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDR-----------------------------------------------------------DWDRERRLP---------------------------------------------------------------------------------------------------------------------------------------------SSPASPSPKG------------------------TPEKAS-------------------------------------------------------------------------ERAGLREGSEEK-------------------------------------------------------------------------------------------------------------------------------------------------VKPPRPRAP------ESDMGD-----------------------------------------------------------------------EDQDQERDAVFLKDNHLAIERKCSSITVSS-------------TSSLEAEVDFTVIGDYHGGAFEDFSRSLPELDR----------------------------------------------------------------------------------------------------------------DKSDSET--------EGLVFAQDL-KGPSSQEDESGGLEDSP---------------------------------------------------------------------------------------------------DRGACSTP----EMPQFESVKAETMTVSSLAIRKKIEPEAMLQSRVSAADST-QVDGGTPMVKDFMTTPPCITTET------------ISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYG------------------------------------------------------------ATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDED-VDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4G0-1", "uniprot_id": "E41L1_HUMAN", "id": "Q9H4G0-1", "name": "Band 4.1-like protein 1", "aln": "MTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVG-NYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKG--FLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG--------------------------AEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVR-----TPTKIKELKPE-------------QETTPRHKQE------------------------------FLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDR-----------------------------------------------------------DWERERRLP---------------------------------------------------------------------------------------------------------------------------------------------SSPASPSPKG------------------------TPEKAN-------------------------------------------------------------------------ERAGLREGSEEK-------------------------------------------------------------------------------------------------------------------------------------------------VKPPRPRAP------ESDTGD-----------------------------------------------------------------------EDQDQERDTVFLKDNHLAIERKCSSITVSS-------------TSSLEAEVDFTVIGDYHGSAFEDFSRSLPELDR----------------------------------------------------------------------------------------------------------------DKSDSDT--------EGLLFSRDLNKGAPSQDDESGGIEDSP---------------------------------------------------------------------------------------------------DRGACSTP----DMPQFEPVKTETMTVSSLAIRKKIEPEAVLQTRVSAMDNTQQVDGSASVGREFIATTPSITTET------------ISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYG------------------------------------------------------------ATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDED-VDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJ90-1", "uniprot_id": "A0AB32TJ90_DANRE", "id": "A0AB32TJ90-1", "name": "", "aln": "--------------------MSERNSATKNPADGG-------------FTDHDSKMSDEHRDTDD---------SSEKTPSRMSRSPQK-SKRPKTVPVKVLLLDGSAYESGVEKLCKGQVLLDMVCEHLNLLEKDYFGLSFSDTECQKNWLDPSKEIKKQIRVGPWHFSFAVKFYPPDPSQLIEDITRYYLCLQLREDILSGRLPCSFVTHALLGSYAIQAELGDYDPEEHGP-DYINEFRFAPNQTRELEERVMELHRTYRGMSPAEAEINFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCASGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRASKRLWKVCIEHHTFFRLVSPEPPPKG--FLVIGSKFRYSGRTQAQSRQASALIDRPAPQFERSISRRYLLSRSIDGESAL---------------GDTMDRLSQHTSSEPVPSLPRDELDQDYLEPSLDQDLDQDHEQEEEQRLESDSTPSKTVELKREEAGSPVDSKTELDQDLTPRPKQEQ-----------------------------FLDKPEDVLQKHQASINELKRALREPNSKLVHREKRLSGASSGSTPEKKSASEESLLIEKQDGCQRDLPLSKKDEKSRSPRVASLATGFNRETDDRVREKNIISVAKRTSTENILSPEKPLRNRAKSPALRYNHFQGINSLDEKAYDNGHSHDRPLSENVIHTNGCDTYATERLWGDKKYMGVTNIEHETTNQDLARYVERSFGEASPNAAMDKYMRDRYNESRCERQSYEKEPENTRATLLKQTSKADPKGKGSTIQRHDSTASDTSQSELKRIVPLKPERSKKLKDRKGAKLQGQPSERSISGSFDESEGINSKEDQVVFENALDTLSQSKNSATLESIGTFAKQDWASNYHNWETREYIRQSVQDRPQLRDLKNNIDHRLSIEQDQFLFDDPLFMFDFPTNS-----------------------------------------------------------------------------------------------TFPAFDQIAPLYPPVKSQRARETRTKPITKSDSGNSLHKSSAMESSKRKSVEPLSTPAIHAEPQEEAQREPWERRLG---------------------------SVSEDDPDPDTLYLKETHLGIERKCSSITVSS-------------TSSLEAEVDFTVLMDFQTG-MEEFSRGMTELGE----------------------------------------------------------------------------------------------------------------KDYSPDFGLSDRPTHPAFILGADPIYLPEERHVEVQRPVEKP---------------------------------------------------------------------------------------------------KPVVEPKPPEERKPEPFVPKKAPRSVKAAQALRKDSTEQANAQSMRRESSESPPIHPLSRESSEIIASQALRKTEVK--IETQPNGSEVTTTIMEIADPDHGISGMREAAYSMTERVSPVCQSFHRVNLGSLARDGS-------------------------------------------------------PLMVTENVTSATTTHVTKTVKGGYSETRIEKRIIITGDDD-VDQDQALAMAIKEAKQQHPDMLVTKAVVVRETESSTQDPHEESKS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V8R9-1", "uniprot_id": "EPB41_DROME", "id": "Q9V8R9-1", "name": "Protein 4.1 homolog", "aln": "-------------------------------------------------MPAEIKPSAP----------------AEPETPTKSKPKSSSSSHGKPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAES--TNTPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKSSTLDHRGDRNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAVDAAAVPLSDSQKRSYSPTKGPQGYSSG------APGSYKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGAAG--AAAAAAKPKKRRVKIMVITSKFDPSTKRIDAENGSIEHSTGILDPATGLIDTKYGVIDPKKGTLEALNTKTGKKEVFQGDVDGKTGNLHLVSGVADPKTGRLDDTLGQIVCITPQDNPVVELTVITSRIDPATGKIDTVNGDVERSLGVLNLDTGLLDTKYGEINTRTGELKAIDPKSGKIVVSKNVKVDPGTGQITILGIVDPKTNKIDPNQGRLIEVGQQIDPIVEVTSLAGKFDSKRNIIDPKTAQVETSGGQFDPKAGKIDTKYGQIDLVKHTITFNDPKSGKTVTRDIKIEPTTGQIVLKNQVNPKNNKPDKDYARIISLRIVQQRVDPATKAPITEVSASKDKDIVVDPKSNQIWVPTGATDPATKEQQYISSSVDPKTGYVITIYGYLDPKTNEIKKQTKLDPNTIKIEPTSGKIYTATGEVDQATGEPLYAATQVDPESGEVYTKLARVDPKTGKIVIVRILLISKTDERGRPEEIDPSTCEIDPVSGRVLKFFNKTVYVYNMIDPVTGEIVQVDPNDPRFAGARTTVTHTMTLTGEIDPVTGRIKSEYGDIDPNTGDIDPATAVTDPVTGKLILNYAQIDPSHFGKQAQVQTTTETVPITRQQFFDGVKHISKGALRRDSEGSSDDDMTAQYGADQVNEILIGSPAGQAGGKLGKPVSTPTVVKTTTKQVLTKNIDGVTHNVEEEVRNLGTGEVTYSTQEHKADATPTDLSGAYVTATAVTTRTATTHEDLGKNAKTEQLEEKTVATTRTHDPNKQQQRVVTQEVKTTATVTSGDQYQRRDSVSSTSSGDSGTPIDGPYDGASVVRTDNQKSPLFTTSATTGPHVESTRVVLGEDTPGFSGHGEIISTQTVSSKTRTVETITYKTERDGIVETRVEQKITIQSDGDPIDHDKALAEAIQEATAMNPDMTVEKIEIQQQTQ-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . .. .:. .. :.: *.. :* ***.* : ::: *: ::: :* ***:*******:: . :.*** .* :.* :* ..* ::*:******:*:** ******:****:* **: *****:********** :*:*:**:*.** *:.::::***** ***:::*:**:*::* :*.***:::*******:******* ******:********.***:***:****************** :*********:**:********.***::*:*** *:********::*** .*. * *:**.:**.*****:: :.: :**..* *:*: * ***:*. .: . . . . :. ... :* * * . :: :: . *.: ** ::* . . * :: * . *: . :: : .. ..*. .* .*:: . : .. : :.. .: ... *. . :. *:..: :: *...* *.: :**::.:..:.: . : : .:*. . .. : : : . . * .. . .. : :*: :. .: . : : ::: . . * :.: . ...: : . : : . : : * .... : :. * . ** :.* ***:*::* * .* * :*:*:*** **:**. :*** * * : ::*: ", "identical_positions": 252, "similar_positions": 256, "identity": "14.11%" }, { "cls_id": "homologset.agr.HGNC:33781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCA8-1", "uniprot_id": "M0RCA8_RAT", "id": "M0RCA8-1", "name": "Purple acid phosphatase", "aln": "MPSGGLRGSPDFGKQEGDERKMLRARPRWMGTPELRPPVGLRHLLHHSPQRRFSHSAFLPHGHPDRRTEGPAWHRSILHPLWDPPTEFDPTPAFLDTSHHPPTMSPFLGGWLF-CLLLLFSLG------VQGTPEYPRATPEQVHLSYPGE--PGTMTVTWTTWAP-------ARSEVQFGTQLSG--PLPLRAHGTSSAFVDGGVLRRKLYIHRVTLRKLLPGAHYVYRCGSSQGWSRRFRFTALKNG-VHWSPRLAVFGDMGADNPKALPRLRRDTQQGMFDAVLHVGDFAYNMDQDNARVGDRFMRLIEPVAASLPYMTCPGNHEQRYNFSNYKARFSMPGDNEGLWYSWDLGPAHIISFSTEVYFF-LHYGRHLVEKQFRWLERDLQKANK--NRVARPWIITMGHRPMYCSNADLDDCTRHESRVRKG---LQGKLFGLEDLFHKYGVDLEFWAHEHSYERLWPIYNYQVFNGSL-ERPYTNPRGPVHIITGSAGCEELLTPFVRKARPWSAVRVKEYGYTRMHILNGTHLHIQQVSDDQDGKIVDDVWVVRPLLGRMMYH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BX37-1", "uniprot_id": "ACP7_MOUSE", "id": "Q8BX37-1", "name": "Acid phosphatase type 7", "aln": "-------------------------------------------------------------------------------------------------------MSPFLGGWLFFCMLLPFSPG------VQGAQEYPHVTPEQIHLSYLGE--PGTMTVTWTTWAP-------ARSEVQFGSQLSG--PLPFRAHGTARAFVDGGVLRRKLYIHRVTLRKLQPGAQYVYRCGSSQGWSRRFRFTALKNG-VHWSPRLAVFGDMGADNPKALPRLRRDTQQGMFDAVLHVGDFAYNMDQDNARVGDRFMRLIEPVAASLPYMTCPGNHEQRYNFSNYKARFSMPGDNEGLWYSWDLGPAHIISFSTEVYFF-LHYGRHLIEKQFRWLENDLQKANK--NRVARPWIITMGHRPMYCSNADLDDCTRHESRVRKG---LHGKLFGLEDLFHKYGVDLEFWAHEHSYERLWPIYNYQVFNGSL-ESPYTNPRGPVHIITGSAGCEELLTPFVRKPRPWSAVRVKEYGYTRMHILNGTHMHIQQVSDDQDGKIVDDVWVVRPLLGRMMYH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNF0-1", "uniprot_id": "ACP7_HUMAN", "id": "Q6ZNF0-1", "name": "Acid phosphatase type 7", "aln": "-------------------------------------------------------------------------------------------------------MHPLPGYWSCYCLLLLFSLG------VQGSLGAPSAAPEQVHLSYPGE--PGSMTVTWTTWVP-------TRSEVQFGLQPSG--PLPLRAQGTFVPFVDGGILRRKLYIHRVTLRKLLPGVQYVYRCGSAQGWSRRFRFRALKNG-AHWSPRLAVFGDLGADNPKAVPRLRRDTQQGMYDAVLHVGDFAYNLDQDNARVGDRFMRLIEPVAASLPYMTCPGNHEERYNFSNYKARFSMPGDNEGLWYSWDLGPAHIISFSTEVYFF-LHYGRHLVQRQFRWLESDLQKANK--NRAARPWIITMGHRPMYCSNADLDDCTRHESKVRKG---LQGKLYGLEDLFYKYGVDLQLWAHEHSYERLWPIYNYQVFNGSR-EMPYTNPRGPVHIITGSAGCEERLTPFAVFPRPWSAVRVKEYGYTRLHILNGTHIHIQQVSDDQDGKIVDDVWVVRPLFGRRMYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5D6U8-1", "uniprot_id": "ACP7_DANRE", "id": "A5D6U8-1", "name": "Acid phosphatase type 7", "aln": "-------------------------------------------------------------------------------------------------------MAAAPPPPPPLLLLLLCVCA------VFADVPIG-TQPEQVHISYPGV--QNSMLVTWSSANK-------TDSVVEYGLWGGK--LFSHSATGNSSIFINEGAEYRVMYIHRVLLTDLRPAASYVYHCGSGAGWSELFFFTALNES-VFFSPGFALFGDLGNENPQSLSRLQKETQIGTYDVILHIGDFAYDLYEDNGRIGDEFMKQIQSIAAYVPYMTCPGNHEWAFNFSQYRARFSMPGDTEGLWYSWNVGPAHIISFSTEVYFYYLEYGLDLLFRQYEWLRADLQEANRPENRAERPWIITMGHRPMYCSNDDDDDCTHFQSYVRLGRNDTKPPAPGLEELFYQYGVDLELWAHEHTYERLWPVYDYKVFNGSS-EEPYVNPKAPVHIITGSAGCREKHDGFIPKPRDWSAFRSTDYGYTRLQLINNTHLYLEQVSDDQYGKVIDQMTLVKEKHGPDAWR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JB52-1", "uniprot_id": "X2JB52_DROME", "id": "X2JB52-1", "name": "Purple acid phosphatase", "aln": "-------------------------------------------------------------------------------------------------------MQRLQFALLASLLLLVLLLPGIRSTPIDQDVDIVHYQPEQVHLSFGAERTDSEIVVTWSTRSLPPDQEVGAVSVVEYGQLVDGQVRLTQQARGKATKFVDGGHKQATQFIHRVTLRDLEPNATYSYHCGSDFGWSAIFQFRTVPSASVDWSPSLAIYGDMGNENAQSLARLQQETQRGMYDAIIHVGDFAYDMNTKNARVGDEFMRQIETVAAYLPYMVVPGNHEEKFNFSNYRARFSMPGGTENMFYSFDLGPVHFVGISTEVYYF-LNYGLKPLVFQFEWLREDLAKANLPENRNKRPWIILYGHRPMYCSNENDNDCTHSETLTRVG--WPFVHMFGLEPLLYEFGVDVAIWAHEHSYERLWPIYDYKVRNGTLKDSPYNDPSAPVHIVTGSAGCKEGREPFKGKIPEWSAFHSQDYGYTRLKAHNRTHIHFEQVSDDKNGAIIDDFWLVKSKHGSYRN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :** : ***:*:*: . . : ***:: : * *::* . :. * *. *:: * :**** * .* * . * *:*** *** * * :: .. . :** :*::**:* :*.:::.**:::** * :*.::*:*****:: .*.*:**.**: *:.:** :***. ***** :***:*:*******..*.::**:::**.*::.:*****:: *.** . : *:.**. ** :** ** ***** ********* : :***: :: .* * *** *::::***: :*****:******:*:*:* **: : ** :* .****:******.* * ***.: :*****:: * **::::*****: * ::*:. :*: * ", "identical_positions": 182, "similar_positions": 122, "identity": "32.16%" }, { "cls_id": "homologset.agr.HGNC:33782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBG6-1", "uniprot_id": "D3ZBG6_RAT", "id": "D3ZBG6-1", "name": "peptidyl-tRNA hydrolase", "aln": "MQRKMRPAILMIRKMAGSG-VEPQILVQYLVLRKDLSQAPFSWPTGALVAQACHAATAALHLHRDHPHTAAYLRELGRMRKVVLEAADETTLKELAETLQQKNVDHTLWLEQPENIATCIALRPYPKEEVSQYLKKFRLFK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z4S3-1", "uniprot_id": "PTRD1_MOUSE", "id": "D3Z4S3-1", "name": "Putative peptidyl-tRNA hydrolase PTRHD1", "aln": "MHRKVRPASLMIRKMACSG-VEPQILVQYLVLRKDLSQAPFSWPTGALVAQACHAATAALHLHRDHPHTAAYLRELGRMRKVVLEAADETTLKELAETLQQKNIDHTLWLEQPENIATCIALRPYPKEEVSQYLKKFRLFK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6GMV3-1", "uniprot_id": "PTRD1_HUMAN", "id": "Q6GMV3-1", "name": "Putative peptidyl-tRNA hydrolase PTRHD1", "aln": "MHRGVGPAFRVVRKMAASG-AEPQVLVQYLVLRKDLSQAPFSWPAGALVAQACHAATAALHTHRDHPHTAAYLQELGRMRKVVLEAPDETTLKELAETLQQKNIDHMLWLEQPENIATCIALRPYPKEEVGQYLKKFRLFK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VET3-1", "uniprot_id": "Q9VET3_DROME", "id": "Q9VET3-1", "name": "peptidyl-tRNA hydrolase", "aln": "--------------MSN--------IVQYIVVRSDLRSA-LSWPLGAVIAQSCHATAAVIHLNSEDADTVAYLNDLDNMHKVVLEAKDESALVKLSEKLKENEIKHKLWIEQPENIPTCIALKPYVKDTVHKYVKHLKLLKE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5RIN6-1", "uniprot_id": "Q5RIN6_DANRE", "id": "Q5RIN6-1", "name": "peptidyl-tRNA hydrolase", "aln": "--------------MATPGSGSSRRLVQYVIVRSDLIHS-LSWPLGAVITQACHAATAAIHLHYSDPDTQQYLAELDSMHKVVLQAPDEASLSTLSSTLEEKDIAHKLWMEQPENIPTCLALKPYPKETVQPYLKKFKLFK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :***:::*.** : :*** **:::*:***::*.:* : ....* ** :*. *:****:* **::* *:..*::::: * **:******.**:**:** *: * *:*:::*:* ", "identical_positions": 54, "similar_positions": 45, "identity": "38.03%" }, { "cls_id": "homologset.agr.HGNC:33783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADJ5-1", "uniprot_id": "D4ADJ5_RAT", "id": "D4ADJ5-1", "name": "Hairy and enhancer of split-related protein HELT", "aln": "-----------MTLSVEKSKVVWKGDRDRVHNWRE-----LTLGGWWPRPKALAFSLVVAGRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFP----------------------------------------------------RGREKAELLAEFANYFHYGYHECMKNLVHYLTT--------VERMETKDTKYARILAFLQSKARLGAEPAFPPL--------------------SLPEPDFSYQLHPAGPEFPGHSP--GEATVFPQGATPGSFPWPPGAARSPALP-----YLSSATVPLPTPAQPHSPFLAPMQGLDRHYLNLIGHG----------HPNTLNLHTP--------QHPPVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TS99-1", "uniprot_id": "HELT_MOUSE", "id": "Q7TS99-1", "name": "Hairy and enhancer of split-related protein HELT", "aln": "-----------------------MSDR-----------------------------LKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFP----------------------------------------------------RGREK-ELLAEFANYFHYGYHECMKNLVHYLTT--------VERMETKDTKYARILAFLQSKARLGAEPTFPPL--------------------SLPEPDFSYQLHAASPEFPGHSP--GEATMFPQGATPGSFPWPPGAARSPALP-----YLSSATVPLPSPAQQHSPFLAPMQGLDRHYLNLIGHG----------HPNGLNLHTP--------QHPPVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFD8-3", "uniprot_id": "HELT_HUMAN", "id": "A6NFD8-3", "name": "Hairy and enhancer of split-related protein HELT", "aln": "-----------------------MSDK-----------------------------LKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFP----------------------------------------------------RGREKAELLAEFANYFHYGYHECMKNLVHYLTT--------VERMETKDTKYARILAFLQSKARLGAEPAFPPLG-------------------SLPEPDFSYQLHPAGPEFAGHSP--GEAAVFPQGSGAGPFPWPPGAARSPALP-----YLPSAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHA----------HPNALNLHTP--------QHPPVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6QB00-1", "uniprot_id": "HELT_DANRE", "id": "Q6QB00-1", "name": "Hairy and enhancer of split-related protein helt", "aln": "---MNARALYKRPPPVSSSQSEASGKRRTRTLDALGFDNYIICNYRLVFYEMMASKMKDRKKTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQNSGKLEKAEILEMTVQYLRALHSADFP----------------------------------------------------RGREKGELLTEFANYFHYGYHECMKNLVHYLTT--------VERMETKDTKYARILAFLQSKVVT--EPVFGSLG-------------------TIS-PDPTDLLCQL--EYQSPSP--TES-VFQQ-SPPGHFSWHS-STRSPTLA-----YPAMS---------QHSGYLSPVQGLDHHYMNFIGH-------------NAFSLHNA--------QHAAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGZ5-1", "uniprot_id": "CWO_DROME", "id": "Q9VGZ5-1", "name": "Transcription factor cwo", "aln": "MEPYWNETNGHAAHPVKYESEAAVSSFPYCTESSLNFSTSATAYSEDDAEYATGRRNKTSRQDPLSHRIIEKRRRDRMNSCLADLSRLIPPQYQRKGRGRIEKTEIIEMAIRHLKHLQSECQQKESDYRSGYMDCMKEAAKFLYDVHMQDFCHRLLGRLQEHIDEMFKTDCYKSTRSCHMPDNVSASSGSPHQAYHPPLCHLRDMLATSASDVEHSQDHNDVKDLSFRNHLNQLQRSQQAAAAAAVAAAAVAVANGSSPASNAGVDSKVPLTNGGGTGGAPPAADNVPSNSTGSGSAAACAGGNSNSSGSNSSNAASSTICPPAGGSCPAKVTPLAAHQQPHQAPVITSTAPHHHHHHTDSSHHDFESSREPILHTDTSNMHSPPPRDLLLQQHPHLAHSHHTQDSLMSVRMRNYSESSHEIEHNNNYKYKNHIKERFVHELHDEETSSEHCPVAAHLQSDHSHLQALSEHSKDGTEPEIAPIMAKKRKLAEAAANGEIPLEVHTESSNAGASSANRLDKPSPSFNFSDIKDIKAELHNGNSNSSPLLAKLSAVAAAGGQLSTPSSTTAPLPPRHTFTVPIFALHGQGNYYVPLNVDYNALVPFLNGMDLLEKSYTSMPVVHPININVNFMPSSPSASLLAAAAAAAVAVGKQQQQQAVVAAGAGLPLSTNSAAAQAAAVAAAAVAKAKLEQAMNQSW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : *:**::********:* ** :*.: :* ::. *::**:**:**::::*: *:* *. . : :: :. * .** : :* . *:* :: :.** .: . * ** . ... . .:. . : : . *. .: . . . :: *. . . :: ::. .:*: . .* : .:*.. **. : ", "identical_positions": 45, "similar_positions": 83, "identity": "6.45%" }, { "cls_id": "homologset.agr.HGNC:33784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPQ8-1", "uniprot_id": "ALKMO_RAT", "id": "A0JPQ8-1", "name": "Alkylglycerol monooxygenase", "aln": "MRNPGAQDNVSVSQGMRAMFYMMKPSETAFQTVEEVPDYVKKATPFFIFLILLELVVSWILKGKPSGRLDDILTSMSAGVVSRLPNLFFRSLEVTSYIYIWENYRVCELPWDSPWTWYLTFLGVDFGYYWFHRMAHEINIIWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFVPPSVFAVHIQFNLLYQFWIHTEVIRTLGPLELVLNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFKVQFHHLLYIWTTFWATPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEVTGQEVPFTSSASQFLKIYAVLQFAVMLVFYEETFANTAVLSQVTILLRICFIILTLTSIGFLLDQRPKAAIVETLRCLLFLTLYRFGHLKPLIESLSFAFEIFFSVCIAFWGVRSITHLASGSWKKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BS35-1", "uniprot_id": "ALKMO_MOUSE", "id": "Q8BS35-1", "name": "Alkylglycerol monooxygenase", "aln": "MRSPGAQDNVSVSQGMRAMFYMMEPSETAFQTVEEVPDYVKKATPFFIFLILLELVISWILKGKPSGRLDDALTSISAGVVSRLPSLFFRSLEVTSYIYIWENYRLLELPWDSTWTWYFTFLGVDFGYYWFHRMAHEINIFWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFIPPSVFAVHIQFNLLYQFWIHTEIIRTLGPLEVILNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFNVQFHHLLYIWTTFWTTPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEVTGQEVPFSSSASQLLKIYTVLQFAVMLAFYEETFANTAVLSQVTLLLRIFFFILTLTSIGFLLDQRSKAATMETFRCLLFLTLHRFGHLKPLIPSLSFAFEIFFSVCIAFWGVRSITQLTSGSWKKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNB7-1", "uniprot_id": "ALKMO_HUMAN", "id": "Q6ZNB7-1", "name": "Alkylglycerol monooxygenase", "aln": "MKNPEAQQDVSVSQGFRMLFYTMKPSETSFQTLEEVPDYVKKATPFFISLMLLELVVSWILKGKPPGRLDDALTSISAGVLSRLPSLFFRSIELTSYIYIWENYRLFNLPWDSPWTWYSAFLGVDFGYYWFHRMAHEVNIMWAGHQTHHSSEDYNLSTALRQSVLQIYTSWIFYSPLALFIPPSVYAVHLQFNLLYQFWIHTEVINNLGPLELILNTPSHHRVHHGRNRYCIDKNYAGVLIIWDKIFGTFEAENEKVVYGLTHPINTFEPIKVQFHHLFSIWTTFWATPGFFNKFSVIFKGPGWGPGKPRLGLSEEIPEVTGKEVPFSSSSSQLLKIYTVVQFALMLAFYEETFADTAALSQVTLLLRVCFIILTLTSIGFLLDQRPKAAIMETLRCLMFLMLYRFGHLKPLVPSLSSAFEIVFSICIAFWGVRSMKQLTSHPWK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYE4-1", "uniprot_id": "ALKMO_DANRE", "id": "Q6NYE4-1", "name": "Alkylglycerol monooxygenase", "aln": "MAQVEAN-NVTVSQGFRMLFSLMTPEESSFATVEEVPKYVNQATPYFIGLILLEIVLGWLKTDGPHIKINDFITSLSAGMMSRLPQLMMRSVELSAYIYIWDNFHFLELPWDSAWTWWLAFLGVDMGYYWFHRFAHELNILWAGHQVHHSSEYYNLSTALRQSVTQQFSSWIFYSPLALLIPPSVFAVHIQFNLLYQFWIHTELVKDLGPLELILNTPSHHRVHHGRNPYCIDKNYAGILIIWDRMFGTFAPESDKVIYGLTHPIGTFEIWSVEFLYYPYLWQRFWEVEGISNKLSVIWKGPGWTPGKPRLGDIADIPQITGEEKPHDPAWSPVMQAYVILQFFLLLDVYNSLLLDQMILSELTVILLTAYVLLSLTSLGFLIDQRSNAAELEMLRCVLIMLLHRFGYIKPLLPALAFPMEAFILISTIYWSLQSVKQRTDKMKKQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *: :*:****:* :* * *.*::* *:****.**::***:** *:***:*:.*: .. * :::* :**:***::****.*::**:*:::*****:*::. :*****.***: :*****:*******:***:**:**.**.***** *********** * ::**:**.****::****:***:*************::. *****::************** ********* *****::**** .*.::*:*******.*** .*:* : :* ** . *: :*:**::***** ******* :**::**:* *. .: * .:: *.::** ::* .*:. : : **::*::* :.:*:***:***:***.:** :* :**:::: *:***::***: :*: .:* .: :. :*.::*:.: :. * ", "identical_positions": 239, "similar_positions": 139, "identity": "53.47%" }, { "cls_id": "homologset.agr.HGNC:33785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AB26-1", "uniprot_id": "A0A8I6AB26_RAT", "id": "A0A8I6AB26-1", "name": "", "aln": "MTAGSPGDRG-ARRSPEGRVSRLGRRLGRRRRPRSPPEPLRVRARLRLRSPSGAFAALGALVVLVGMGIAVAGYWPG-------RASHAHVPRT-------------GRAHGPHERLRLLGPVIMGVGLFVFICANTLLYENRDLETRRLRRGVLRAQALRPPDGPGWD----------------------------------ALLPSPAHGSPGAV--AEPETWDLAPRRGPSPVPSVRSLRSEPAN--------------------PRSGLPALLHSYPLKGPG--------LPPPWG--------PRTQTGHVIITVQPSGSCIEHSKSLD-----------LGLGELLLGAPAARDCAHRSWPRLDRLSLGGYAKLGG--DLGARV---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z0P8-1", "uniprot_id": "D3Z0P8_MOUSE", "id": "D3Z0P8-1", "name": "", "aln": "MTAGSPGDGG-ARRSPEGRVSRLGRRLGRRRRPRSPPEPLRVRARLRLRSPSGAFAALGALVVLVGMGIAVAGYWPG-------RASHTHAPRT-------------GRAHGPHERLRLLGPVIMGVGLFVFICANTLLYENRDLETRRLRRGMLRAQALRPPDGPGWD----------------------------------ALLPSPAHGSPGAV--AEPETWDLAPRRGPSPVPSVRSLRSEPAN--------------------PRSGLPALLHSYPLKGPG--------LPPPWG--------PRTQTGHVIITVQPSGSCIEHSKSLD-----------LGLGELLLGAPATRDCAHRSWPRLDRLSLGGYAKLGG--DLGARV---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69YZ2-1", "uniprot_id": "T200B_HUMAN", "id": "Q69YZ2-1", "name": "Transmembrane protein 200B", "aln": "MTAGSPEECGEVRRSPEGRVSRLGRRLGRRRRPRSPPEPLRVRARLRLRSPSGAFAALGALVVLVGMGIAVAGYWPHRAGAPGSRAANASSPQMSE---LRREGRGGGRAHGPHERLRLLGPVIMGVGLFVFICANTLLYENRDLETRRLRQGVLRAQALRPPDGPGWDC---------------------------------ALLPSPGPRSPRAVGCAEPEIWDPSPRRGTSPVPSVRSLRSEPAN--------------------PRLGLPALLNSYPLKGPG--------LPPPWG--------PRTQTGHVIITVQPSGSCIEHSKSLD-----------LGLGELLLGAPAARDCAHRSWPRLDRLSLGGYAKLGGGGDLGARV---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKP7-1", "uniprot_id": "A0A0R4IKP7_DANRE", "id": "A0A0R4IKP7-1", "name": "", "aln": "--MRTQKSRG--RTSATHSRQRLPRFSLHSRRKKEG----VIQGKLRIRSMPGAFLVLGVVVVVVGTALAVAGYWPYRAHRSSLDTVEEGSSGTASGWGLGSKGLFSAASLVHSERMKLLGPVIMGVGLFILICANTVLYENRDRETQMLLAQMRSVICSVSAAVPSADLLQVNSLARHYQWVSSLPAAHLNILCLQEMSSSEPLLQVKSMDEEDSIQQQDTVHTEVLHHQDSSSTPSVHSSNSCNNSKEVLCMDEQRTTSALDLRQESHFALSNCMTASSMSTLGGEECEIFPIPPRRSYSMNHRTKPQILPRNLVHPEDKSVSSMGHHRLLPRQSSSEVCINMVGVDIKTLDLIPVEEQRHRSWPRLDLGSARKYLKLENKEDSVEKLLDQLEQQCLQMNKSYGSGPFQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * *. .** * : ** :. ::.:**:** .*** .**.:**:** .:******* : . . . : **::************::*****:****** **: * : . . .. *. * .** . . :: :. : ::..*..***:* .* . .: .*. : : .:. * :** . *: . ::: . : * *.: * : * :*:. *. ...: ******** * * ** . * :: ", "identical_positions": 90, "similar_positions": 85, "identity": "21.9%" }, { "cls_id": "homologset.agr.HGNC:33787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D853-1", "uniprot_id": "EFMT2_MOUSE", "id": "Q9D853-1", "name": "EEF1A lysine methyltransferase 2", "aln": "MNADAEGHSGAVVPAQSPEGSSAADDFVPSALGTREHWDAVYERELRTFQEYG-DTGEIWFGE-ESMNRLIRWMQK----HKIPLDAS-VLDIGTGNGVFLVELV---------------------------KHGFS-NITGIDYSPSAIKLSASILEKEGLSN-INLKVEDFLNPSTKLSGFHVCVDKGTYDAISLN---PDNAIEKRKQYVMSLSRVLE-VKGFFLITSCNWTKAELLDAFSEG-FELFEELPTPKFSFGGRSGNTVAALVFQKRGTSLDKIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLB6-1", "uniprot_id": "A0A8I5ZLB6_RAT", "id": "A0A8I5ZLB6-1", "name": "EEF1A lysine methyltransferase 2", "aln": "MNADAEGNSGAVVSAQSREGSPVADDFVPSALGTREHWDAVYERELKTFQDYG-ATGEIWFGE-ESMYRVIRWMQK----HKIPLDAS-VLDIGTGNGVFLVELVDLNYHSVVGVVVNSLCMEILILANEEVKHGFS-NITGIDYSPSAIKLSASILEKEGLSD-VNLKVEDFLNLSTKLSGFHVCVDKGTYDAISLN---PDNAVEKRKQYVMSLSRVLE-VKGFFLITSCNWTKAELLDAFSEG-FELFEELPTPKFSFGGRCGNTVAALVFQKRETSLDKVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JPI9-2", "uniprot_id": "EFMT2_HUMAN", "id": "Q5JPI9-2", "name": "EEF1A lysine methyltransferase 2", "aln": "MSSGADGGGGAAVAARSDKGSPGEDGFVPSALGTREHWDAVYERELQTFREYG-DTGEIWFGE-ESMNRLIRWMQK----HKIPLDAS-VLDIGTGNGVFLVELA---------------------------KFGFS-NITGIDYSPSAIQLSGSIIEKEGLSN-IKLKVEDFLNLSTQLSGFHICIDKGTFDAISLN---PDNAIEKRKQYVKSLSRVLK-VKGFFLITSCNWTKEELLNEFSEG-FELLEELPTPKFSFGGRSGNSVAALVFQKM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5D013-1", "uniprot_id": "EFMT2_DANRE", "id": "Q5D013-1", "name": "EEF1A lysine methyltransferase 2", "aln": "MNSSVSTHGTGDCPVNCTK----SEDFAPSKLGTKEYWDGAYKRELQTYKDIG-DVGEIWFGE-ESMHRVIRWMEA----QNISENAA-ILDIGTGNGMFLVELA---------------------------RHGFS-NLTGIDYSKAALELTTNILVEEGLKN-INIQVEDFLNPSTELKGFDVCIDKGTFDAISLN---PEDREEAKKHYVTSLRAVMR-PNGFFIITSCNWTKEQLLEIFKPG-FELVRELPTPNFQFGGVTGNSVTALVFKQTD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQJ8-1", "uniprot_id": "Q9VQJ8_DROME", "id": "Q9VQJ8-1", "name": "Protein-lysine N-methyltransferase CG9643", "aln": "MDSELNG----------------------SELGTKEFWESSYNREIRNYKSHG-DVGEIWFDE-SAQWRTIDWLLNE---EKIDKEASRVLDLGCGNGMFLVGLA---------------------------NEGFTGDLTGVDYSPKAVELAQNIAEDNKLS--ITYKVADLTQPQNELGQFDVVHDKGTYDAVSLC---PDNAKEKRALYLDTVEKLLRTADSLFVITSCNWTEDELVDSFAEK-FVKYYTIPTPTFKFGGKVGNVVTSIVFKRKKE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40516-1", "uniprot_id": "EFM4_YEAST", "id": "P40516-1", "name": "Protein-lysine N-methyltransferase EFM4", "aln": "MQGTADLS--------------------TSKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS-VVDLGTGNGHMLFELH---------------------------QTEFQGKLVGIDYSEESVKLASNIAEATGVDNFISFQQADIFSGDWKPGKYDIVLDKGTLDAISLSGMKINGKLDVVDVYAGVVERILK-KDGIFLITSCNFTQDELVKIIETDNLKMWKTIKYPVFQFGGVQGATICSVAFVKQN-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. . * ***::.*: * *:..:: .*: **.: .: : * :: .* :*: ::*:* *** :*. * . * .:.*:*** :::*: .* :. :. : *: . . : :.: **** **:** :. : * : ::. ..:*:*****:*: :*:. : : : * *.*** * : ::.* : ", "identical_positions": 53, "similar_positions": 77, "identity": "18.6%" }, { "cls_id": "homologset.agr.HGNC:33788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q569A3-1", "uniprot_id": "CK087_RAT", "id": "Q569A3-1", "name": "Uncharacterized protein C11orf87 homolog", "aln": "MSARAPKELRLALPPCLLNRTFASHNASGGSNAGIRSSGAGG-GTCITQVGQQLFQSFSSTLVLIVLVTLIFCLIVLSLSTFHIHKRRMKKRKMQRAQEEYERDHCSGSHGGGGLPRAGVQAPTHGKETRLERQPRDSAFCTPSNATSSSSSS---PGLLCQGPCAPPPPPPVPSPHGAHAASSCLDTPGEGLLQTVVLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32M26-1", "uniprot_id": "CK087_MOUSE", "id": "Q32M26-1", "name": "Uncharacterized protein C11orf87 homolog", "aln": "MSARAPKELRLALPPCLLNRTFASHNASGGSSAGLRSSGAGG-GTCITQVGQQLFQSFSSTLVLIVLVTLIFCLLVLSLSTFHIHKRRMKKRKMQRAQEEYERDHCSGSHGGGGLPRAGVQAPTHGKETRLERQPRDSAFCTPSNATSSSSSSSSSPGLLCQGPCAPPPPLPAPTPQGAPAASSCLDTPGEGLLQTVVLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUJ2-1", "uniprot_id": "CK087_HUMAN", "id": "Q6NUJ2-1", "name": "Uncharacterized protein C11orf87", "aln": "MSARAPKELRLALPPCLLNRTFASPNASGSGNTGARGPGAVGSGTCITQVGQQLFQSFSSTLVLIVLVTLIFCLIVLSLSTFHIHKRRMKKRKMQRAQEEYERDHCSGSRGGGGLPRPGRQAPTHAKETRLERQPRDSPFCAPSNASSLSSSS---PGLPCQGPCAPPPPPPASSPQGAHAASSCLDTAGEGLLQTVVLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************ ****...:* *..** * *******************************:**********************************:*******.* *****.************.**:****:* **** *** ********** *..:*:** ********.***********", "identical_positions": 170, "similar_positions": 18, "identity": "85.0%" }, { "cls_id": "homologset.agr.HGNC:3379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K162-1", "uniprot_id": "A0A0G2K162_RAT", "id": "A0A0G2K162-1", "name": "", "aln": "MTTEVASASEVKKGSDPSGADAHKEKAKEVVENEQTAASELDEGKASQPGPTAESQSSPHRRKRGKDPSENRGISRFIPPWLKKQKSYSLVVAKDGGDKKEPTQADGEDQILDKEDTLPEEESRAKGDAEEMAQRKHLEVKVEVREEKSALK-------SSAEIQPAEQVRKDKEEEVIQDIQEEKLEGGAAKRETKEVQTSELKAEVASQKAAKKTKTVLAKVTLLDGTEFSCDLEKRAKGQALFDRVCEHLNLLEKDYFGLIFQEHPEQKNWLDPAKEIKRQLRSLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDISSGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDS-IDLGDFQFAPTHNKELEEKVAELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPGELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPK-TKFLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASS--KRVSRSLDGAPIGVVDQSLMKDFPGPPGEGSVPGPGVVSYTTVQDG-------------------------------RRDGKSPTKVTPL-LAEGKKNTLRVDGDNIYVRHS------------------------------------------------------NLMLEDLDKAQEAILKHQASVS---------------------------------------------------------ELKRNFMESTPEPRPSEWEKRRVTPLSCQILARNSQTLFKDILSAKLMSQMAAARTPEEATQVHKTPRALVSEGPCT---------------------------------------------------------------------------------------------------------------------------------------------GTRDAVKSSHETLNVVEEKKRAEVGKGE----------------------------------------SVITEEMNGKELSPGSGPGETRKVEPMAHKDSTSLSSESSSSSSESEE-DVGEYQPHHRVTEGTIREEQE------------------------------------------------------------------------------------------------YEEELEEEPGQGAKVVEREAAMPEAIPDRQAG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASVLPVETEAQENVVAQKLPGEKGAHRGTAEQDMSEEAEEDQHRVN-----------------------------------------------------------GEVPHLDIDGLPEIVCPSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQ-------------------------------IDGGAGGDSGVLLT-------------------------------------------------AQTITSESASTTTTTHITKTVKGGISETRIEKRIVITGDAA-LDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70318-1", "uniprot_id": "E41L2_MOUSE", "id": "O70318-1", "name": "Band 4.1-like protein 2", "aln": "MTTEVGSASEVKKGSDQAGADASKEKAKEVE-NEQTPVSEPEEEKGSQPGPPVERQSTPRLRKRGKDPSENRGISRFIPPWLKKQRSYNLVVAKDGGDKKEPTQADVEDQILGKEESLPEEESRAKGDAEEMAQRKHLEVQVEVREAKPALK-------SSVETQPAEEVRKDKEE-TIQDTQEEKLEGGAAKRETKEVQTSELKAEVASQKATKKTKTVLAKVTLLDGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDHPEQKNWLDPAKEIKRQLKNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDS-IDLGDFQFAPAHTKELEEKVSELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPK-TKFLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASS--KRVSRSLDGAPIGVVDQS-------PPGEGSVPGPGVISYTTIQDG-------------------------------RRDSKSPTKATPL-PAEGKKNTLRVDGDNIYVRHS------------------------------------------------------NLMLEDLDKAQEAILKHQASIS---------------------------------------------------------ELKRNFMASTPEPRPSEWEKRRVTPLPFQPQA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSHETLNVVEEKKRAEVGKDE----------------------------------------SVITEEMNGKEMSPGHGPGETRKVEPVAHKDSTSLSSESSSSSSESEE-DVGEYQPHHRVTEGTIREEQEE-----------------------------------------------------------------------------------------------CDEELEEEPGQGAKVVEREAAVPDAVPDRQAG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASVLPVETEAQEHVVAQKLPGEKGAHGGTAEQDPREEAEEDPHRVN-----------------------------------------------------------GEVPHLDLDGLPEIICCSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQ-------------------------------IDGGAGGDSGVLLT-------------------------------------------------AQTITSESASTTTTTHITKTVKGGISETRIEKRIVITGDAA-LDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43491-1", "uniprot_id": "E41L2_HUMAN", "id": "O43491-1", "name": "Band 4.1-like protein 2", "aln": "MTTEVGSVSEVKKDSSQLGTDATKEKPKEVAENQQNQSSDPEEEKGSQPPPAAESQSSLRRQKREKETSESRGISRFIPPWLKKQKSYTLVVAKDGGDKKEPTQAVVEEQVLDKEEPLPEEQRQAKGDAEEMAQKKQ-EIKVEVKEEKPSVSKEEKPSVSKVEMQPTELVSKEREE-KVKETQEDKLEGGAAKRETKEVQTNELKAEKASQKVTKKTKTVQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLDPAKEIKRQLRNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAELGDYDPEEHGS-IDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPK-AKFLTLGSKFRYSGRTQAQTRQASTLIDRPAPHFERTSS--KRVSRSLDGAPIGVMDQSLMKDFPGAAGEISAYGPGLVSIAVVQDGDG-----------------------------RREVRSPTKAPHLQLIEGKKNSLRVEGDNIYVRHS------------------------------------------------------NLMLEELDKAQEDILKHQASIS---------------------------------------------------------ELKRNFMESTPEPRPNEWEKRRITPLSLQTQG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSHETLNIVEEKKRAEVGKDE----------------------------------------RVITEEMNGKEISPGSGPGEIRKVEPVTQKDSTSLSSESSSSSSESEEEDVGEYRPHHRVTEGTIREEQE------------------------------------------------------------------------------------------------YEEEVEEEPRPAAKVVEREEAVPEASPVTQAG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASVITVETVIQENVGAQKIPGEKSVHEGALKQDMGEEAEEEPQKVN-----------------------------------------------------------GEVSHVDIDVLPQIICCSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQ-------------------------------IDGGAGGDSGTLLT-------------------------------------------------AQTITSESVSTTTTTHITKTVKGGISETRIEKRIVITGDGD-IDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V8R9-1", "uniprot_id": "EPB41_DROME", "id": "Q9V8R9-1", "name": "Protein 4.1 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPAEIKPSAPAEPETPTKSKPKSSSSSHGKPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAES--TNTPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKSSTLDHRGDRNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAVDAAAVPLSDSQKRSYSPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGAAGAAAAAAKPKKRRVKIMVITSKFDPSTKRIDAENGSIEHSTGILDPATGLIDTKYGVIDPKKGTLEALNTKTGKKEVFQGDVDGKTGNLHLVSGVADPKTGRLDDTLGQIVCITPQDNPVVELTVITSRIDPATGKIDTVNGDVERSLGVLNLDTGLLDTKYGEINTRTGELKAIDPKSGKIVVSKNVKVDPGTGQITILGIVDPKTNKIDPNQGRLIEVGQQIDPIVEVTSLAGKFDSKRNIIDPKTAQVETSGGQFDPKAGKIDTKYGQIDLVKHTITFNDPKSGKTVTRDIKIEPTTGQIVLKNQVNPKNNKPDKDYARIISLRIVQQRVDPATKAPITEVSASKDKDIVVDPKSNQIWVPTGATDPATKEQQYISSSVDPKTGYVITIYGYLDPKTNEIKKQTKLDPNTIKIEPTSGKIYTATGEVDQATGEPLYAATQVDPESGEVYTKLARVDPKTGKIVIVRILLISKTDERGRPEEIDPSTCEIDPVSGRVLKFFNKTVYVYNMIDPVTGEIVQVDPNDPRFAGARTTVTHTMTLTGEIDPVTGRIKSEYGDIDPNTGDIDPATAVTDPVTGKLILNYAQIDPSHFGKQAQVQTTTETVPITRQQFFDGVKHISKGALRRDSEGSSDDDMTAQYGADQVNEILIGSPAGQAGGKLGKPVSTPTVVKTTTKQVLTKNIDGVTHNVEEEVRNLGTGEVTYSTQEHKADATPTDLSGAYVTATAVTTRTATTHEDLGKNAKTEQLEEKTVATTRTHDPNKQQQRVVTQEVKTTATVTSGDQYQRRDSVSSTSSGDSGTPIDGPYDGASVVRTDNQKSPLFTTSATTGPHVESTRVVLGEDTPGFSGHGEIISTQTVSSKTRTVETITYKTERDGIVETRVEQKITIQSDGDPIDHDKALAEAIQEATAMNPDMTVEKIEIQQQTQ-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : .:.. . . .... :.: *.. .:******: . .::::* *: ::: :* ***:******* :: .: :.*** * :.: ::. .* :** ******:****.******.****:*:** .*****:********** :*:* ****.** : * :*::** :. ***:** :*****:* ***:*: ::*****:*:******* ********* *****.***:*:*:****************** :****:**.*:**:********.******:*** *******:**::** .* * .:**.:**.*****:: :.* :**..*:*:*: * : .***:*. .:. :: . . * : ::: .: :.. *.. * *:*:: . * ::**:* . *::.* : * *: .. :. . ** : *. : .: *:** **.. *. : ***..:: . . *: .: : : *: *.:: .. .:.: * .. : :. : *.. .:: : .::: ** . *::.: : * : . : : . * . * : * * *: .:* .:::: ***.: : .: . . . * .. : :: * *:. * * **:: .: :.. :.****. : .* * .* : *. * ** :.** ***:*::*.* .*. :***:***:**:** :***:* :: ::::*: ", "identical_positions": 287, "similar_positions": 260, "identity": "15.15%" }, { "cls_id": "homologset.agr.HGNC:33790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9N4-1", "uniprot_id": "A0A8I6A9N4_RAT", "id": "A0A8I6A9N4-1", "name": "", "aln": "---MLRAVWLRLCAALCSLLLG--RAEAPSP-G--------VPPERSRP-------------YTVLRGQN-----LVL------------MGTVFSILLVT------------VVLMAFCVYKP---IRRR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N812-1", "uniprot_id": "CL076_HUMAN", "id": "Q8N812-1", "name": "Uncharacterized protein C12orf76", "aln": "MFQNLQGTFEKEIGKIIPFTIAFKRAEAVEPDGCVQSWRCCLPCDLGQASRFIHTTVCSAIRWRSCKGERNFAERHILPAELEEQSNHAGMGPILPAMPSVDGNHFQHPAGDCHPYGILCLQAHSASVTARQVLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:..: : . : .: :. **** .* * :* : .:. : :*:. :* **.::. : . :*: : * ", "identical_positions": 14, "similar_positions": 31, "identity": "10.37%" }, { "cls_id": "homologset.agr.HGNC:33792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR22-1", "uniprot_id": "D3ZR22_RAT", "id": "D3ZR22-1", "name": "", "aln": "MSEADPSSGFAGSVENGTFLELFPTSLSTSVDSSSGHLSNVYIYVSIFLSLLAFLLLLLIIALQRLKNIISSSSSYPEYPSDAGSSFTNLEVCSISSQRSTFSNLSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CD78-1", "uniprot_id": "SRTM1_MOUSE", "id": "Q8CD78-1", "name": "Serine-rich and transmembrane domain-containing protein 1", "aln": "MSEADSSSGFAGSVENGTFLELFPTSLSTSVDSSSGHLSNVYIYVSIFLSLLAFLLLLLIIALQRLKNIISSSSSYPEYPSDAGSSFTNLEVCSISSQRSTFSNLSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2A2V5-1", "uniprot_id": "SRTM1_HUMAN", "id": "A2A2V5-1", "name": "Serine-rich and transmembrane domain-containing protein 1", "aln": "MSEPDTSSGFSGSVENGTFLELFPTSLSTSVDPSSGHLSNVYIYVSIFLSLLAFLLLLLIIALQRLKNIISSSSSYPEYPSDAGSSFTNLEVCSISSQRSTFSNLSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*.****:*********************.**************************************************************************", "identical_positions": 103, "similar_positions": 4, "identity": "96.26%" }, { "cls_id": "homologset.agr.HGNC:33795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEH8-1", "uniprot_id": "A0ABK0LEH8_RAT", "id": "A0ABK0LEH8-1", "name": "Nutritionally-regulated adipose and cardiac enriched protein homolog", "aln": "MVASSFVDTGDCQMRSAAPVSHPNPHPRTRHPTRENEGTTWGSQPPRTERDDDRKCPPSILRPRRQECGCPGGEPQRNQRHVRFREPLEVAVHYIARKDRTAAIKVPRRAAPHGGSPLQPAFCGGSLFLWLILCVLLGVVLGLYCGRAKYVTGALEDLWAQLLVLTSRLWRAVLACWHCLLQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNX7-1", "uniprot_id": "NRAC_MOUSE", "id": "Q8BNX7-1", "name": "Nutritionally-regulated adipose and cardiac-enriched protein", "aln": "-------------MRSAARVSRSNSHPRTRHPTRENEGTTWGSQPSRTERDGDRKCPPSILRPRRQECGCHGGEPQKTSRHVRFREPLEVAVHYIARKDTTAAIKVPSRPASHGGSPLQPASCSGSLFLWLTLCALLGVVLVLYCGQAKRVTAALEDLLAQLLALILRLWRVVLACWH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N912-1", "uniprot_id": "NRAC_HUMAN", "id": "Q8N912-1", "name": "Nutritionally-regulated adipose and cardiac enriched protein homolog", "aln": "-------------MRTAAGAVSPDSRPETRRQTRKNEEAAWGPRVCRAEREDNRKCPPSILKRSRPEHHRPEAKPQRTSRRVWFREPPAVTVHYIADKNATATVRVPGRPRPHGG----------SLLLQLCVCVLLVLALGLYCGRAKPVATALEDLRARLLGLVLHLRHVALTCWRGLLRL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:** . .:.:*.**: **:** ::**.: *:**:.:********: * * .:**:..*:* **** *:***** *: **:::** *. .*** **:* * :*.** :.* ****:** *: ***** *:** * :* :..*:**: ", "identical_positions": 77, "similar_positions": 45, "identity": "42.08%" }, { "cls_id": "homologset.agr.HGNC:338", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35351-1", "uniprot_id": "AGTR2_RAT", "id": "P35351-1", "name": "Type-2 angiotensin II receptor", "aln": "MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35374-1", "uniprot_id": "AGTR2_MOUSE", "id": "P35374-1", "name": "Type-2 angiotensin II receptor", "aln": "MKDNFSFAATSRNITSSRPFDNLNATGTNESAFNCSHKPSDKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLALADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKGSSLREMDTFVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50052-1", "uniprot_id": "AGTR2_HUMAN", "id": "P50052-1", "name": "Type-2 angiotensin II receptor", "aln": "MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* ::*:**:****. *. :* :*.***::***:**:****:***:***:****** ******:********************:**************************************************************************:**********************************************************************************************************************:***:***********************************************************:*****.******:****", "identical_positions": 332, "similar_positions": 25, "identity": "91.46%" }, { "cls_id": "homologset.agr.HGNC:3380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2J2-1", "uniprot_id": "E41L3_HUMAN", "id": "Q9Y2J2-1", "name": "Band 4.1-like protein 3", "aln": "MTTESGSDSESKPDQEAEPQEAAGAQGRAGA-PVPEPPK-------EEQQQALEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGS-DYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKK--FLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDG---------------------EVGTGQYATTKGISQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPIS----------------------------------------------------------------------------------------------------------------------AIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEED---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AELKAQELEKTQDDLMKH--------------------------------------------------QTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQE---------------------------DAPMIEPLVP--------------------------------------------------------------------------------EETKQSSGEKLMDGSEIFS-------------------------------------------------------------------------LLESARKPTEFIGGVTSTSQSWVQKMETKTES--------------------------------------------SGIETEPTVHHLPLSTEKVVQETVLVEE---------------------------------------------------------------------RRVV--HASGDASYSAGDSGDAAAQPAFTG---IKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEP---------------GVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDAD-IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WV92-1", "uniprot_id": "E41L3_MOUSE", "id": "Q9WV92-1", "name": "Band 4.1-like protein 3", "aln": "MTTESGSDSESKPDQEAEPQEAAGPQGQAGAQPGPEPAGGNGSLNGEKQQPALEQFPEAAAHSTPVKREIGDKDRDFAAAAAKQLEYQQFEDDKLSQRSSSSKLSRSPLKIVKRPKSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQIRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGN-DYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKK--FLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVSENHEIYMKDSVSAA---EVGTGQYATTKGISQTNLITTVTPEKKAEEERVEEEDRRKKAEEATPVT----------------------------------------------------------------------------------------------------------------------ALRHEGK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDSERTDTAADGETSATESDQEED---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEIKAQDLDKTQDELMKH--------------------------------------------------QTNISELKRTFLETSTETALTNEWEKRLSTSPVRLAARQE---------------------------DAPMIEPLVP--------------------------------------------------------------------------------EETKQSSGEKLMDGSEILS-------------------------------------------------------------------------LLESARKPTEFIGGVSSTTQSWVQKLETKTEP--------------------------------------------VEAEVESTPHPQPLSTEKVLQETILVEE---------------------------------------------------------------------RHVMSVHASGDASHTARDEVDAAESTPTDRRHTGKGKEGSSVTEAAKEQRGEEVDQSAPEQEQPATVSHE--EEQASTIRTSEGLEQKSHFESSTVRVESTSVGSISPGGAKLEISTKEVPVVHTETKTITYESSQVDPGADLEP---------------GVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDAD-IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V8R9-1", "uniprot_id": "EPB41_DROME", "id": "Q9V8R9-1", "name": "Protein 4.1 homolog", "aln": "------MPAEIKPSAPAEPETPTKSK----------------------------------------------------------------------PKSSSSSHG----------KPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAES--TNTPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKSSTLDHRGDRNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAVDAAAVPLSDSQKRSYSPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGAAGAAAAAAKPKKRRVKIMVITSKFDPSTKRIDAENGSIEHSTGILDPATGLIDTKYGVIDPKKGTLEALNTKTGKKEVFQGDVDGKTGNLHLVSGVADPKTGRLDDTLGQIVCITPQDNPVVELTVITSRIDPATGKIDTVNGDVERSLGVLNLDTGLLDTKYGEINTRTGELKAIDPKSGKIVVSKNVKVDPGTGQITILGIVDPKTNKIDPNQGRLIEVGQQIDPIVEVTSLAGKFDSKRNIIDPKTAQVETSGGQFDPKAGKIDTKYGQIDLVKHTITFNDPKSGKTVTRDIKIEPTTGQIVLKNQVNPKNNKPDKDYARIISLRIVQQRVDPATKAPITEVSASKDKDIVVDPKSNQIWVPTGATDPATKEQQYISSSVDPKTGYVITIYGYLDPKTNEIKKQTKLDPNTIKIEPTSGKIYTATGEVDQATGEPLYAATQVDPESGEVYTKLARVDPKTGKIVIVRILLISKTDERGRPEEIDPSTCEIDPVSGRVLKFFNKTVYVYNMIDPVTGEIVQVDPNDPRFAGARTTVTHTMTLTGEIDPVTGRIKSEYGDIDPNTGDIDPATAVTDPVTGKLILNYAQIDPSHFGKQAQVQTTTETVPITRQQFFDGVKHISKGALRRDSEGSSDDDMTAQYGADQVNEILIGSPAGQAGGKLGKPVSTPTVVKTTTKQVLTKNIDGVTHNVEEEVRNLGTGEVTYSTQEHKADATPTDLSGAYVTATAVTTRTATTHEDLGKNAKTEQLEEKTVATTRTHDPNKQQQRVVTQEVKTTATVTSGDQYQRRDSVSSTSSGDSGTPIDGPYDGASVVRTDNQKSPLFTTSATTGPHVESTRVVLGEDTPGFSGHGEIISTQTVSSKTRTVETITYKTE--RDGIVETRVEQKITIQSDGDPIDHDKALAEAIQEATAMNPDMTVEKIEIQQQTQ--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **. ***: .: .: :****. . *. .:* ***** .::::: *: :::.:* ***:*********. . : :.*** * :.* .*:.:* ::* ******:*:**.******:****:*:**:.*****:*** ****** ****:****.:* . *:.:*::***:* ******::***:*:* :*****:*:*******:******* *******:***********:***:**********:*******::************:********.******:*** **********: **. .*. * .:**.:**.*****:: :.: :**..* *:*: * ***:*. . . *: : . *.:.: : . * *::: *:*::.:* .* : *: ::*: *.. ..:** . : *: : .: *::.:: .*. *:: * :: : . ** :..: .::*.: : . :*. : * : : .**: * .. *..*::** * .::: . ::: : ..* *. ::.::: . . * .. . :.:.* . *:: ::..: . :.: .. : .:*:.:::: : * . : : :: : : *: .:: ::: ::* .: . . .. : :: * * . .*. :: . . ..**:*:.:. . ::.. .*..:*. * ::*:**::*:* :. * *: *: :.** ***:*::*.* .*.* ****:***:**:**. :***:* *: ::::*: ", "identical_positions": 305, "similar_positions": 299, "identity": "16.98%" }, { "cls_id": "homologset.agr.HGNC:33800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810M6-1", "uniprot_id": "LIAT1_MOUSE", "id": "Q810M6-1", "name": "Protein LIAT1", "aln": "-------------------MAGRGGTGAAEYGEEG--------------EEEEEEEAREGGAEGSPGSKLPPIVGTASELAKRKVKKKKKKKKTKGSGKGDADKHHSRGRKNQPLSSSFHDILNPHKDHGLRAEPRDKEENRQTLP-YSYSINHPCFAEIEDTLSSQINESLRWDGILTDPEAEKERIRIYKLNRRKRYRLMALK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFHSDPCVEESVENLPYLSDKDCSPCSKQPSSKGDHAHSYFEA---SKLLHPELATTVAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRL2-1", "uniprot_id": "D3ZRL2_RAT", "id": "D3ZRL2-1", "name": "", "aln": "-------------------MASRSGTGVVEYGEEG--------------EEEEEEEVREGGAEGSPGSKLPPIVGTTSDLAKRKVKKKKKKKKTKGSGKGD-DKHHSRGRKNQPLSSSFHDILNPHRDHGSRAEPRDKEETRQTLP-YSYSMNHPCFAGIEDSLSSQINESLRWDGILADPEAEKERIRIYKLNRRKRYRLVALK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFHSDPCVEESVENLPYLSDKECSPSSKQPSSKGDHAHSYFEA---SKLPHPELATTAVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQX7-1", "uniprot_id": "LIAT1_HUMAN", "id": "Q6ZQX7-1", "name": "Protein LIAT1", "aln": "METRGPGLAVRAESRRLVGIGPRAPPGRVGLQPSGRLDRRGGAGTMGYKDNDGEEEEREGGAAGPRGSRLPPITGGASELAKRKVKKKKRKKKTKGSGKGD-DKHQSQSLKSQPLSSSFHDILSPCKERGPKPEHRQSKVEKKHLPSDSSTVSLPDFAEIEN-LANRINESLRWDGILADPEAEKERIRIYKLNRRKRYRCLALKGFHPDPEALKGFHPDPDALKGFHPDPEALKGFHPDPEALKGFHPDPEALKGFHPDPEALKGIHPDPEALKGIHPDPEALKGFHPDPEALKGFHPDPEALKGFHTDPEALKGFHIDPEALKGFHPDPKALKGFHPDPKALKGFHTDPEALKGFHPDPKALKGFHPDPEALKGFHPDPEALKGFHPDPEALKGFHTDPNAEEAPENLPYLSDKDGSSSHRQPTSKAECPNLCFEGNLTPKLLHSDLAPTLLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *. .* . .* ::: *** ***** *. **:****.* :*:**********:*********** ***:*:. *.***********.* :::* :.* *:.: :: ** * ::. * ** **: *:.:***********:********************* :*** **:** .**: *********: *.. :**:**.: .: **. .** *.:**.* *", "identical_positions": 134, "similar_positions": 56, "identity": "29.45%" }, { "cls_id": "homologset.agr.HGNC:33802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D5S1-1", "uniprot_id": "TX19B_MOUSE", "id": "Q9D5S1-1", "name": "Testis-expressed protein 19.2", "aln": "MCPPVSVRHGAKGMSCLYGAWLYHLVHGEQMKICFACFKAAFLVVKNMLEMGDW----------EEGVWDAEPMELSEAS----SEPEEWPGLSG----------------GEGQGHLPHGISVSAGSGAQ------------GPQPVPTELGPQEAVPLDLGPEDAEWTQALPWRFDGLSPCSHWLIPPLSWWEIFNVSPSPGQPVLLELSPTWPMDPLEAEAWLVGLKFVFLLGGFDAICYMLSMTPCWAVRTRVQRWQVLLDPGDVRVAQLQNAPEQQ-----DLHRWKLSVLESSELGMELVPADCSLQKGGFKVHSYLPWHNSTPESWSREPGERLLVVEVVSLRELPCFRSPSPDPHN----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXL6-1", "uniprot_id": "D3ZXL6_RAT", "id": "D3ZXL6-1", "name": "", "aln": "MCPPVSVRHGAKGMSCLYGAWLYQLVHGEQMKICFACFKAAFLVVKNMLEMGDW----------EEEVWDAEPMELSEAG----SEPEEWPGLSW----------------GEGQGHTPHGISASTGSGAQAPGLVGTEGTGQGPQPVPTELGPQEAVPLDLGPEDAEWTQALPWRFDGLSPCSHWLIPPLSWWDIFNASPSPGQPVLLELSPTWPMDPLEAEAWLVDLKFVFLLGGFDAICYMLSMTPCWAVRTRVQRWQVLLDPGEVRVAQLQNAPEQQ-----DLHRWKLSILESSELGVELVPADCSLRKGGFKVHSYLPWHNSTPEAWNREPGERLLVIEVVSLRELPCFRSPSPEPHN----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MV2-1", "uniprot_id": "TX19A_MOUSE", "id": "Q99MV2-1", "name": "Testis-expressed protein 19.1", "aln": "MCPPVSVRHGARGMSCLYEAWLYHLVHGEQTKICFACFKAAFLLNKLYLEMGDWQEEE--EEEEEE---DADLLEYLSES---ESESEQEPGPEQ------------DAWRGLGSLYVPQSVSE--GSGVLLPTPVWTQG-ILFSIFVPTELFPQEAVPLDLGPEDAEWTQALPWRLDGLFPCSHQLIPPLTWWDIFDVMPSPGQPVLLELRCHWPLDQTVAQSWLQDQKFVLLLDSVQSRCHLLSMRVRWVVRTQVQHWQVLLDPGEMWVAHFRKEVGQHGLYHQSLNPWRLSILTASELGMELLPATCYLWNKGFWVGSFLPWHINMPETWSWEPGERLFITDATICGTDYHLAQSFLDSHPTPHPLLTLTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XHY3-1", "uniprot_id": "TX19A_RAT", "id": "Q5XHY3-1", "name": "Testis-expressed protein 19.1", "aln": "MCPPVSVRHGARGMSCLYGAWLYQLVHGEQMKMCFACFKAAFLLNKFYLEMGYWEQEELSEEEEEEEVWDAEPMEHLSESESLESDSKQDAGSEQDAGSEPNTRSEQDAWQGVGSLYVPQSVSEYGGPGALVPTPSWTQW-VVFSISVPTELLPQEAVPLDLGPEDVEWTQALPWRLDVLFPCSHRLIPPLSWWDILDVMPSLGQPVLLELRSLWPLDQSVAQTWLQDQKFVLLLDSIHFMCHLLSMHVCWAVRTQVQHWQVLLNPGEMWVAHLKRVLFRP----RGLYPWSLSILKSSDLGMELVPAAFYLRKKGFWVGSFLPWNSSIPETWSWDPGERLFITDATICATNYHFARSFFP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NA77-1", "uniprot_id": "TEX19_HUMAN", "id": "Q8NA77-1", "name": "Testis-expressed protein 19", "aln": "MCPPVSMRYEEEGMSYLYASWMYQLQHGDQLSICFTCFKAAFLDFKDLLESEDW----------EEDNWDPELMEHTEAE----SEQEGSSGMELS--------------WGQSPGQPVQGGSEAWGPGTLAAAPEGLEDAGLDPHFVPTELWPQEAVPLGLGLEDADWTQGLPWRFEELLTCSHWPS----------FFPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*: .*** ** :*:*:* **:* .:**:******* * ** * ** *.: :* . *: : .* . * . :. * *.*. . ***** *******.** **.:***.****:: * .*** ** ", "identical_positions": 70, "similar_positions": 31, "identity": "18.72%" }, { "cls_id": "homologset.agr.HGNC:33803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BP01-1", "uniprot_id": "VMAC_MOUSE", "id": "Q8BP01-1", "name": "Vimentin-type intermediate filament-associated coiled-coil protein", "aln": "MSAPPPLQIREANAHLAAVHRRAAELERRLLAAERTIGAQAERLACHDQHLRAALDELGRAKDREISALQEQLLSSEATVRSLQAAVDQRDQMIQQLQPRADLLQDITRHRPPLAALLATLEEAEELGPLPAS-HSHRAQLLPDGPG--PP--LGN----NMGKEEGQDDQDDQQPAVFGTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6QZQ4-1", "uniprot_id": "VMAC_RAT", "id": "Q6QZQ4-1", "name": "Vimentin-type intermediate filament-associated coiled-coil protein", "aln": "MSAPPPLQIREANAHLAAVHRRAAELERRLLAAERTMRAQAERLACQDQQLRAALDELGRAKDREIFTLQEQLLSSEATVRSLQAAVEQRDQMIQELQPRADLLQDITRQRPPLAALLATLEEAEELGPLPSS-HSHGAQLLPDGPG--PP--LGN----SMREEEGQD---DQQPAVFGTTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2NL98-1", "uniprot_id": "VMAC_HUMAN", "id": "Q2NL98-1", "name": "Vimentin-type intermediate filament-associated coiled-coil protein", "aln": "MSAPPALQIREANAHLAAVHRRAAELEARLDAAERTVHAQAERLALHDQQLRAALDELGRAKDREIATLQEQLMTSEATVHSLQATVHQRDELIRQLQPRAELLQDICRRRPPLAGLLDALAEAERLGPLPAS-DPG--HPPPGGPG--PP--LDN----STGEEADRD---HLQPAVFGTTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QC89-1", "uniprot_id": "A0A2R8QC89_DANRE", "id": "A0A2R8QC89-1", "name": "", "aln": "MSSPSPVQIREANAHLAALHRRVSELEQRLREAERTVREQAESLIRKDEQLRAATQEITEAKDKEIFFLHEKLCQSEESIHKLNQTIKEKDSLIGQLQHRCQLLDNICKSRPLLDSMLAQMAEAERMGPVSDLGKPTTNSSLTDGESNCSPSRLSNHKDFSLSEDDSDDQ--ELDGVVFGTTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*..:***********:***.:*** ** ****: *** * :*::**** :*: .***:** *:*:* ** :::.*: ::.::*.:* :** *.:**::* : ** * .:* : ***.:**:. .. ..* . .* *.* . :: . * . : .******", "identical_positions": 75, "similar_positions": 56, "identity": "40.98%" }, { "cls_id": "homologset.agr.HGNC:33808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZVW7-1", "uniprot_id": "I17EL_HUMAN", "id": "Q6ZVW7-1", "name": "Interleukin-17 receptor E-like protein", "aln": "MLAGQALAFLGLTWGTFQSLAIPRITECGLSCSQGFACRSHRNRNIFNSFCRPRPVSMSRSVLEALTSSTAMQCVPSDGCAMLLRVRASITLHERLRGLEACAMSLDTQETQCQSVWVARASHRQQGGQQLQVHFGCFAVSVAQHLYVTLRTIPHFCGVQLDQRHLVEDCGEEDVGRSVPDCLAGKLSYWVDRRRKAILVQVPRASGSPDYYLRLCLKR-FTCEDAGAPVRVTANSVSQAVFLPYSQELPCLCLEGWSATPDAVRIQICPFENDTEALEVLWDTVYYHPESQTLSWEPACPVSGHVSLCWRPGPGAGCRKLQQSSQLVHRRVQYPLVDTQPQLCLKFSTSWGSWVRCPFEQRRFPTWKMTIQPSPTKGHLRVTFFSSSPAHFQVHLCHRRKSQLPACQRTLQASPLPSASGDLAAAPAFAFLDLPREEACAPGICIQGWRTDVHFSVPQQLCNLRSSGCPSLRGRRRPRTRPRPPTAGWAWR------ALNRRLGGGNGETIRP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RS12-1", "uniprot_id": "A0A8M1RS12_DANRE", "id": "A0A8M1RS12-1", "name": "", "aln": "MICFWLPLLLLLQKHTVQMERIERNQDCGWNCSEGLQCKPRAYSPLSAFHCRNQPISS--AVFNDVMLSTVLACEERK-CSLQLRMATSVNVTGNIRGVSVCADSAGMIG-HCQIYTFGRVGGFNVTGKQVDVRFKCVPVRPGQHLFVTLKTIPNYCKAMWSQRHLVPDCRHEGVRDEVAECITGKLAYTVDKAKKLFSVTVTGAPEDTEYNLRLCHKRNVICAGEGTHKTVKPQHLQRSVQLHYSKALPCLCIEGWPAKVDARRVQVCPFKNN---FEELWSGITYDLRKGELIWEPLCPVKVLVSLCHADGSKS-CRDIGEAFHSDGQKVVFSSVDPHPALCTKFTTEVGTWIRCPFSEGNFSVWTAKMAFK--DGQQWAEISAWVKANFSVSICEMK----PSQCKSIEGSNLKTLSVDKTKPTVFNLS----ESACKVCVCIQVQRVDVLFSVPVLQCDLQCPNWCHDPDSDHSEDIEMILLPAVIFLTVILAVVLFGRLTIKDGDEKKGRLWKKLRCQGMNQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. :* * *.* * * :** .**:*: *:.: : .** :*:* :*:: : **.: * . *:: **: :*:.: .:**:..** * . :** ..*.. : *:*::*:* *..* .***:***:***::* . .***** ** .*.* .*.:*::***:* **: :* : * *. *. ..:* **** ** . * . *: *..: :.::* * **: *****:***.*. ** *:*:***:*: :* **. : *. .. * *** ***. **** *. : **.: :: : ::* :. **.:* ** **:*. *:*:****.: .*..*. .: . .*: . : : *:*.* :*. : *: ::::.* * : * * : ...* : *.** :*** *.** **** *:*:... . :.. .. : .* ** :*: : ", "identical_positions": 166, "similar_positions": 162, "identity": "31.5%" }, { "cls_id": "homologset.agr.HGNC:33809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4F4-1", "uniprot_id": "A0A8I6A4F4_RAT", "id": "A0A8I6A4F4-1", "name": "", "aln": "-----------------MSKAHLLLLLATLVLTSHVHGATLGSEDTWKPLSNPRNRELFFRSLQAYFKRRGLDLGNLPNTFFVNEDPRPLSFESEHIASAFADYEEQKNSLPNSRKG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A5F8MPB3-1", "uniprot_id": "A0A5F8MPB3_MOUSE", "id": "A0A5F8MPB3-1", "name": "", "aln": "-----------------MSQVHLLLLLAALVLTSHVHGATLRNEDTWKPLSNPRNRELFFRSLQAYFKGRGLDLGNLPNTFFLNEDPRPLSFGSEHIASAFADYEEQKNSLRNSYKG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXQ4-1", "uniprot_id": "CB066_HUMAN", "id": "Q6UXQ4-1", "name": "Uncharacterized protein C2orf66", "aln": "MIIDSSRIPSFTQLHSTMTRAPLLLLCVALVLLGHVNGATVRNEDKWKPLNNPRNRDLFFRRLQAYFKGRGLDLGTFPNPFPTNENPRPLSFQSELTASASADYEEQKNSFHNYLKG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::. **** .:*** .**:***: .**.****.*****:**** ****** ******.:**.* **:****** ** *** *********: * **", "identical_positions": 68, "similar_positions": 17, "identity": "58.12%" }, { "cls_id": "homologset.agr.HGNC:3381", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49222-1", "uniprot_id": "EPB42_MOUSE", "id": "P49222-1", "name": "Protein 4.2", "aln": "MGQALSIKSCDFHAAENNEEHYTKAISSQHLTLRRGQSFTITLNFRAPTHTFLSALKKVALIAQTGEQPSKINKTQAIFPISSLGDQKGWSAAVEERDAQHWTVSVTTPVDAVIGHYSLLLQVSGKKQYPLGQFTLLFNPWNRDDAVFLQNEAERTEYVLNQNGFIYLGTADCIQEEPWDFGQFEKDVMDLSLKLLSMDKQVKDWNQPAHVARVVGALLHALKKKSVLPISQTQAAQEGALLYKRRGSVPILRQWLTGQGRAVYETQAWVSAAVACTVLRCLGIPARVVTTFDSAQGTVGSLLVDEYYNEEGLQNGEGQRGHIWVFQTSVECWMNRPDLSQGYGGWQILHPRAPNGAGVLGSCSLVPVRAVKEGELQLDPAVPELFAAVNASCVVWKCCEDGKLELTNSNRKDVGNCISTKVVGSDRCEDITQNYKYPAGSLQEKEVLEKVQKERLKLGKDNGMCPPSCEPWDPLHMFFEASSSIPLSGDGQLSVTLINPTDEEKKVHLVIGAQALYYNGVLAAGLWSKKQLFMLKPNQVMRLSTNLSFSCFEQTPPENSFLRVTAMARYSHTSLSCFAQENMAIGKPDLIIEMPKRAAQYRPLTVSVRMHNSLEAPMQNCIISIFGRGLIHREKRYGLGSLWPGSSLHTQFQFTPTHLGLQRLTVEVDCDMFQNLTGYRSVLVVAPEVSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16452-1", "uniprot_id": "EPB42_HUMAN", "id": "P16452-1", "name": "Protein 4.2", "aln": "MGQALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSKDKQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTVVAPELSA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.******:**.*****:***:**::* :****.*** * ****.::**.******* ***********:*** ********:* ***.******* **:*****.***************:** *************:*****:***:* **:*****:********** *.******* **:****:*** ****:.*.**.*****:***** **:: *** .****:****** ***************:**.**: **** ********************* ***** * **:*****************:**:****.****.** *.***.******* ****.******.********** * * ***.:****:*************.****:** * *** **** **************** **********:*:**::: ****: *** *. .**:::::*.**:** **.*:****:* :::** *:*.**.**::******* ** ** : *..* :: .* ** **:.****:***:**** :*.:.*******::** :*.* *:**::* **:***.** ::***:***::*:***:********: * : *:** .:: ::*******:***********:******.*:** *****:*.", "identical_positions": 505, "similar_positions": 123, "identity": "73.08%" }, { "cls_id": "homologset.agr.HGNC:33814", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M632-1", "uniprot_id": "F1M632_RAT", "id": "F1M632-1", "name": "Adenylate kinase 9", "aln": "MASEEKTEE-HPFADIFNEDETDRNCLLSKPACFIIFGKPGVGKTTLARSIAQAWKCIRVEAISVLEEHIAAENETGTMLQSLLVSGHTVPDELVTKLVLEKIKSPEVSHFGYILTEIPSLSQDNMTSLKQIEIIKHLELQPDVIINIKCSDYDLCQRISGQRQHSTTGYIYTREQWDPEIIESRRKKKKEVLKEGKAEEEEEEEQEEEEEAFLAEMQMVTETLQYLVQRPEDYLENIEVTVNLYKELLLNALEEVMAEHNPQYLIELDGNKPPEELFLTVIERLKYLNVRRAAIITKLQG-TEEEMTDIIDTEELFRTVSSYKLMGPRYRWNRSKWARACPVSLKDGNIYPGAADFSVSFLGKMYCLSSEETLKLFLLNPRPFLLPPMPLPPCKVFIFGPNHSGKTTLANLIAEHFKAKVIDYATLVQPRFDSAREKLIKDTISEATNTAIKLVKERLLNDLRVKKQEEKTLKELRMHYTKKEYEDFSDYKKTKSSEEFPSSADDPEAQGSRNLSALEIGPEDKSRSENTISGDTDKD-------------------------------GSPEELIEEVTENHPEVFAMIEDTLRHSKELNFEQPYDKQAEILEEVIKEVTKDNKNRFAGAPKYGGWIVKN-FPIMRELWMSLIEKALLPDLVVNLSDTESNGKIVLTRLYLSNKAEINAKILERLKEELQVKKREEDEIRKVKEEELRLEEEKQRMMELEAKKAK-------------VVEEPDN-EAEEEVDVEESEIHEETEAQEMGELARESSIPGGSESSEVPEAEHDPEAEFKAPEDTAVEAETEKGSKETLELEEQLK-AMLPEFPEDGYPNVPEMEPLKEVLANYLIAWKQLEPIISDSLVPVLTVDISNKTPKELLQRVIEMMEKPFKYGAWELNAEDYEEEAEDYQAEMEVEEEQEEEEEEEEEGEEKSKERRRHLGDTKHFCPVVLKENFVLQPGSTEEAVKYREKIYYFSTPEAKEKFLEHPEDYVSQNEPLKAPPLRICLLGPHGSGKTVCARKLAENFGIFHIQFEEFLQERMLLKAERKFGPEFEDDSEEE-----------QAMKQELEELAAQANVKIEEDNTK---KQLPEVQFTEEEEAIKLSLTDNEPLPSEILDPMLSEWWLKEPIRSTGFILDGFPRYPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQLKKSERKKMIKEMKAKIKEDMVAKRRAELISEREKRKKGEGAFR-----DEEEFSDEDAEDE---DDIENILEEEFPKDEEEMS-EEDEEQEGDATERLRSELGEKFETETNNIQSIQDEFERFLIPIIPVNGARKMHIVQYVLNVKLKPLVENRASIFEKCYPVSPHLAHKMLAFTYKHMSSFGYWDPVKLSEGETIKPVETAENPLNPIIHRHYIYFLSTKQTKEKFMMNPIKYIRQPKPKASMPVRIMIVGPPKSGKSTVAKQLANDYGLKCLSMGDALRGMLSNHPEAELSLRINWHLHKGMTVPDDLAIQALDISLLDSVCNTVGVVIDGYPVTPHQVELLEARSIIPMIIFELDVPSKEIFKRLLLEKKSEQGMPYPMHNSTQIIAYRNAKYRKNVNEIRQFYQRQHQNWHVIDGFHSKWWVWNEVIKDIQQMNKYIQTYMEKIKEGKAACIDKLCITPEELISRLGEFKQFCPVSLAESNELIDCSVTSSLEFTAEFRGHYYKMSSQEKLNKFLKNPELYVPPLAPHPLPPDDMLPKRLTLSELKSRFPMSAELQGYCPVTYKDGKQRYEALVPGDNEYAVEYRGRIYICESEEKLQKFLRLPMKYWDQKLPHKLPPPKESIHLTSLPLPGYLEQGTATSLIKAMNAAGNLKPKLPFLSVRRSVLLYIAFHLKAFNPKGSEYSRKKYKKKMEQFVERCELITYLSSKMTRKFKEPQFRPIDFDHKLQTFMSLKNIDPVTG--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UYQ4-1", "uniprot_id": "KAD9_MOUSE", "id": "G3UYQ4-1", "name": "Adenylate kinase 9", "aln": "MASEEKTEELHPFTDIFNEDETDRNCLLSKPTCFIIFGKPGAGKTTLARNIAQAWKCIRVEALSVLEEHIAAEKETGAMLQSLLVSGHSIPDELVTKLILEKIKSPEVAHFGYILTEMPSLAQDNMTSLKQIELVKNLELQPDIIINIKCSDYDLCQRTCGQRQHSTTGYVYTREQWDPEIIESRRRKKRDFPKEGKSEEEEEEEEQEEEEAFIAEMQMVAEILQHLVQRPEDYLENVEITVKLYKELLLSALEEVMAEHNPQYLIELDGNKSPEELFMTVIERLKYLNVRRAAVITKLQG-TEEEMTDIIDTEELFRTVSSYKLIAPRYRWYRSKWARSCPVSLKDGNIYSGAADYTVSFLGKMYCLSSEETLKLFSLNPRPFLLPPMPLPPCKVFIFGPEHIGKTTLANLIAEHFKAKVIDYAKLVQPRFDSAREKLIKDTITEATNTAIKVVQQRLLNEKQAKQQEERTLKELQVQYSKREYNDFLS----KSSEELPS----LENTGS-KLSSLEIGQEDKSKSETTITGDQVKD-------------------------------VSTEESIEEVTENHPEVFAILEDTLRHAKELNFEQPHDKQAEILEEVIKETE-DNKNRFPGAPKHGGWIVEN-FPLVRELWLSLIEKALLPDLVVYLSDAESNGKHVLNRLYLKNKAEIDGKILERLQEEAQAKKREEEEIRKVKEEELRLEEEKQRLMELATKKSKGRHRLTTLVAHHLALPYPDYPDNEAEEEVEDSEIHEESEAQEIPEYTRGSSLPEASETSETPEGDHEPEAEFKPPGDTAVEAETEKDPKEGLGSEDLLK-VMLPEFPEDGYPNVPEMEPLKEVLNNHILSWKQLEQTIMDNVVSTLTVDVSNKTPQELLQRVVETMERPFKYSAWELNAEDYEEEAEDYQAETEIDEEQEEEEEEEEEGEEKIKEKRRHMGDTKHFCPVVLKENFVLQPGNPDEAVKYREKIYYFSSTEAKEKFLEHPEDYVSQNEPLKAPPLRICLLGPHGSGKTVCARKLAENFGIFHIQFDEFLQEKMLLKAERKFGPEFEDDSEEE-----------QLVKQELEELAAQANVKIEEDTTK---KQLPDVQLTEEEEAIKLSLTDNEPLPSEILDSILSEWWLKEPIRSTGFILDGFPRHPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQHKKLERKKLIKDLKTKIKEDMVAKRRAELILEREKKRREDGTFR-----DEDEFSDEDADYE---DDIENILEEEFPKDEEEMS-EEDEEQEADATERLRNELGEKFETETNNIQSIQDEFDKVLIPIIMVNGARKMHIVQYVMNMKLKPLVENRESIFEKCYPVSSHLAHKMLSYTYKHMSSFGYWDPVKLSEGETIKPVENAENPLNPVIHRHYIYFLSNKQTKEKFMMNPIKYIRQPKPKATMPVRIMIVGPPKSGKTTVAKKLASDYGLRCLSVGDALRGMLNNHPDSELSLMLNWHLHKGKTVPDELAIQALDISLMESVCNTIGVVIDGYPVTPHQMDLLEARSIIPMVIFELHVPSKEIFKRLLLEKKTEQSMSYPLHNSSQIIAYKNAKYHKNINEIRQFYQKQHQNWHVIDGFHSKWWVWNEVLKDIQQMNKYIQTYMKKIKEGKAACIDKLCITPEELIARLGEFKQFCPVSLAESNELIDCSVTSSLEFAAEFRGHYYKMSSQEKLNKFLKDPELYVPPLAPHPLPPDDLLPKRLTLSELKSRFPKCAELQGYCPVTYQDGKQRYEALVPGNIRYALEYRNCIYICESEEKLQKFMRSPMQYWNQKLPRKLPPLKESIHLTSLPLPGYLEQGTATSLIKAMNAAGNLKPKLPFLSVRRSVLLYIAFHLKAFNPKGSEYSRKKYKKKLEQFVERCELITYLSSKMTRKYKEPQFRAIDFDHKLQTFLSLKNIDPVTG--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TCS8-4", "uniprot_id": "KAD9_HUMAN", "id": "Q5TCS8-4", "name": "Adenylate kinase 9", "aln": "MTSQEKTEE-YPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG-AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFLGKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVVDYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGY----IQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDN-CPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAK-------------EAEETDN-EDEEEIEGDELEVHEEPEASHD---TRGSWLPEEFEASEVP--ETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEE--EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENE-----------QAAKQELEELAIQANVKVEEENTK---KQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRR-ENVVR-----DDEEISEEELEEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKPLVENRASIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYPVIHRQYIYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELSVPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQHQNWYVIDGFHSKWWVWNEVIKNVQMVNKYMQTYLERIKAGKAACIDKLCITPQELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYKMSSQEKLNKFLENPELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRYEALVPGSINYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREPILLTSLPLPGYLEQGIATSLIKAMNAAGCLKPKFPFLSIRRSALLYIALHLKAFNPKGSEYTRKKYKKKMEQFMESCELITYLGAKMTRKYKEPQFRAIDFDHKLKTFLSLRNIDPING--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R9YJL3-1", "uniprot_id": "A0A2R9YJL3_DANRE", "id": "A0A2R9YJL3-1", "name": "", "aln": "MSSDLIVSN-LPLVDKLIEDEAERAILLSKPACFIIIGKPGVGKSTLAKKIAKTWNCILIDDTDVLNNHINNETDQGKQLFRILAEGKAVPEEMMVNLIVDRLKSPDIKHYGYVLACLPSISEEYMKIQEQIDLIKTLKMSPDFIINIKCADRDLIRRLSEERQHPETGCVFPKEKWDPDKKESLMKQSNMEEEEEEEEEGEEETTEDLEVEEIEEIQLQKDVIAQLVRVTENYPENVTSRIKCYKDNILRPLEDYMAGHNPPYLFELDGNTDPEELFESVMSHLEFMAVRCPAVPVQLMPTEDAELTDQMEPEELFRTLSSCRNVAPGFPWRTSRWAFNCPVALKEGKVIKGKPEFAVGFMDKIYVLSSDDALQKFMANPRCYLLQPKPHVPCRVSVIGPPRSGKSTMCGLLAEKYGALVVDVRELMERNQGLLKQDMLNKVRHDATIAGLEKVRAKMELEATA----------------------------------------------------------------------------------------------------------------IEVTEDHPDVQAFVEEAIKEAAES--PAPRELYLDALEKHIKEIEAEDAD----AESKRGWILDIPSSRSHLITIEEIHGALTPEIIFCLKDNDREGRTVLTRMYERNKEEVDQAVMTRLQNQRNLQKTQDHETLKHSEDSKKDSQYSDTLSKLET-------------------------------------VHEESESSDK----------------------------------SDDEGKTPSKNE-----------VVLPTVWENGHPDGPEMDVFKVELKQFVTDWESMEQTITCSYA---VLEINNKTPQGILQEMTDHMEKPFKHKAIMTSSADLEEEEEAIHMLIQAEKQDDVVNEEEEQESEEFN-FKRQLGDTKHFCPVVLKEKGLLQPCLDEYAAKYRDKVYYFSSKEALEKFLQNPELYISNKELLKPPALRVSMLGVRGSGKTTHGKWLAQQLGIFHIQFRERLQELIQRKTQKRVSPADDSEPPEEPPEELQSLLKAQARIQSAESPTDQDNTTSLEETASGSPDAKEEEALTEDEEAIKAYLQNGDPLPSEILEMLLFQWWNQEPYKSTGFILEGFPQNHEEVSFMAEHHLFPDVVAVMSVEVSEVVRRLLPSRLNRWRERRERKQQQIHLVMKLRKEIRERAITKRRAEIMAEQAFRKLSPPTLSPLKEQEEEEEKEEAVDEEQELEEIEAMLLEEFPPEDEEETEDEEQETEESAEERLEVEISERFEKDDDNLTSMTDLLSDNQIPRLVISAGRLPRIVRYQLLKEIKPLMENRDSLFQTCQPISYSLARRLLYCSFKYPSAFGCWDPVKYTEGDLIQPPQDSYHSTFPVILHQFIYFFASKETRNTFILNPIKYLRQPRPNPSLPIKLAIIGPPKSGKTTVAQAFAREYGLTRLSIGDAIRMVLNSQAKTDLACQVQIHLKQGQTVPDELAIQCVEVAVMNLVCTTRGFVLDGFPVTKHQAELLES-CIIPMVVVELQLDTVEVLKRGLRDREKNNRSHQVHHDSLQALNIRNSCFRQEAEALRLHLHNQYHNWTPVDAHKSKWWVQERILDEVRISMRHIHSYLERIHKGQAACINRLCITPQELQSRLGEFGHYCPVSLALHRHLVDCSHNTSLELAAEFKGQFYKMASREFLERFLESPEQFVAPGCPYPLPPASLLPHKLSAGQVKSRFPQQVEMKGFCPVTYLDGKQRYEALLRGNMEYAAEYRNKIYIFESEKKQEQFLRSPETYWDQKLPHKLPPLEEPVLLTSLPILGYLEQSVAVPIIKAMTDVGQLKPKFPFLSVKRSAILYLAFHLKAFNSRNSEYIRQKYKKKLQKFEEGCELISYLSTTMK-TYKSPLNLPTEFLQKLDRFLALEKSTKTDSGLIQLGGI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*: ..: *:.* : ***::* *****.**:::****.**:***: *:::*:** :: :*:::* *.: * * :* .*:::*:*:: :*::::::**:: *:**::: :**:::: *. :**:::* *::.**.******.* ** :* . :*** ** ::.:::***: *. ::.. :: : ** *** :: * : *:*: : : **: .*:* **: :: **: :* .**: ** *** **:**:**. .**** *:.:*::: :: .*: .:* : *:.* :: :*****::* : :.* : * *:*. *** **:*:: * .:::*.*:.*:* ***:::*: * *** :** * * **:* ::** **:*:..::**:: . *:* *:: . . :: :::.. :** :.:: *: :: : . *** :**:* :::*:::: : : * : : *:: : * :: : * . ***:. . : : : *. .: *:::. *.* : :*: ::.*:* :* *:: :: ** :: : :* ::.* * .*:. : .: . : :* :***.*:.. : * : . : .:** . *:.:*: ***: :* : ..: *:.:* * ::: ::**: :**.: : **:**:: * .. * *** * : : ::: : :** : .:: : :*::*************: :*** : *.***:*:****: ** ****::** *::::* **.*.**:.::* :***** .: **:::.****** * *** : *::::..* :.:. :* * *. *. : * *.. *:.:. . : :**:**.** * :.:***.***: :* :** :** :******:***: **..*:.:: :***....:.*: .::. ****:::::*: :: :* :: ::: .:: :*: ::*****:: *: :: .. :::* .:* : : ::** :* :*** ::** : :*::* * .* ***. *:.*:** : .*: : * :. ** : :...* :**:* : ::***:*** *:*:.* *:. **:::* ::*: *:** ***** :**: *:* : : :. *:* :::***::.*:*::.*: *****:***:*:.::*::: *:*******:***: :: :*** **:*.*:* :*..:..::*: :: **::* *.**:****.::::::: **.* *.*:**:*** ** :***: .****::.** : : *::** * :::.:: *:* * : .* :::: :* . :.*::** :*..:***** :.::.::: :::::*:::*: *:****::*****:** :***** ::****** ..*.*** . ***::***:*::***:*:* *::**:.** :*.* .*:***. .::*::*: .::***** .*::*:***** **:******: *. .** **:. *** *.::* ::*:* * **:****:**** .*.: *****: *****. *..:****. .* ****:****::**.:**:*:******.:.*** *:*****:::* * ****:**.:.*. .:*.* . :* :**. *::*.: . ", "identical_positions": 638, "similar_positions": 666, "identity": "32.4%" }, { "cls_id": "homologset.agr.HGNC:33816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZI94-1", "uniprot_id": "D3ZI94_RAT", "id": "D3ZI94-1", "name": "", "aln": "MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKQLPQGPGEVPMASSITTPTPTEEGECQSLVQSGRQEETSRYLDGYCPSASSLAYSALDAKCSGWDRSDRPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQSQGRWDHETIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7E1Z1-1", "uniprot_id": "TM215_MOUSE", "id": "A7E1Z1-1", "name": "Transmembrane protein 215", "aln": "MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKQLPQGPGEVPMASSVTTPTPTEEGECQSLVQSGRQEETSRYLDGYCPSASSLAYSALDAKCSAWDRSDRPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQSQGRWDHETIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68D42-1", "uniprot_id": "TM215_HUMAN", "id": "Q68D42-1", "name": "Transmembrane protein 215", "aln": "MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKPPPQSQGEVSVASSINSPTPTEEGECQSLVQNGHQEETSRYLDGYCPSGSSLTYSALDVKCSARDRSECPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQIQGRWDHETIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************************************************************ **. ***.:***:.:**************.*:**************.***:*****.***. ***: *********************************** **********", "identical_positions": 216, "similar_positions": 13, "identity": "91.91%" }, { "cls_id": "homologset.agr.HGNC:33818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QR77-1", "uniprot_id": "CMI2A_RAT", "id": "Q4QR77-1", "name": "Ciliary microtubule inner protein 2A", "aln": "MTATQKHNLFTPEPHYIPGYAGFYPQLRYQVGNTYGRTTAQLLTDPSVQKSPCSVLSPMSKPKFIEDFSKSKPPWMPCRDLTEPYIPHYTNLKPYKNFEILGKLPRQEVDTQGMPQGENISRHVPLPAGFMPYPPYPPCPPGRKGEARDLGHPGLLLAYGEEAWKNAAPLQETPGRYHQLYHCRRDEYLPPHP-PQETLDVGRYQRLPQLDHPNLIQRKAISGYAGFVPRFAWVMGMNYRDGVIQAMDDFDKNQFVFKHPVCTLGERLPKTHWPTTTIYRSQGLIPFYMGFIPSMQDNYAMTFGNSTRRAYQKELERRSQTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4K5-1", "uniprot_id": "CMI2A_MOUSE", "id": "Q9D4K5-1", "name": "Ciliary microtubule inner protein 2A", "aln": "MTATQKHNLFTPEPHYIPGYAGFYPQLRYQVGNTYGRTTAQLLTDPSVQKSPCSVLSPMTKPKFIEDFSKSKPPWIPCRDLREPYIPHYTSLKPYKNFEILGQLPRQDVDTQGPPQVE--NRQGPLTAGFMPYPPYPACPPGRKGEARDLGHPGLLLAYGEEAWKDAAPLQDTPGKNNQLYHCRRDEYLPPHP-PQETLDVGRFQRLPQLDHPNLIQRKAISGYAGFVPRFAWVMGMNYRDGVTQAMDDFDKNQFVFRHPVCALGERLPRTHWPNTTIYRSQGLIPFYMGFIPSMQDNYALTFGNSTRRAYQKELDRRSHTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6J272-1", "uniprot_id": "CMI2A_HUMAN", "id": "Q6J272-1", "name": "Ciliary microtubule inner protein 2A", "aln": "MTTTQKHDLFTPEPHYVPGYAGFFPQLRYQVGNTYGRTTGQLLTDPSVQKSPCSVLSPMSKPKFIEDFSQSKPPRVPCQDLTEPYIPHYTSLKPSKNFEILGQLPPLEVDAQEPPGVENIPRQILLPAGFTPDTPHPPCPPGRKGDSRDLGHP----VYGEEAWKSATPVCEAP-RQHQLYHCQRDEYPPPARRQQETLDVGSFQRLPQLDHPNLIQRKAISGYAGFIPRFTWVMGLNYRDGVMQAMDEFDKSQFLFRNPHCDLGEKLPGTHWPSNHIYSSQGLIPFYMGFIPAMQDNYALTFGNSTRRAYWKEWAKRNHTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:****:********:******:***************.*******************:*********:**** :**:** ********.*** *******:** :**:* * * *: *.*** * .*:*.*******::****** .*******.*:*: ::* : :*****:**** ** ******* :***********************:***:****:****** ****:***.**:*::* * ***:** ****.. ** *************:******:********** ** :*.:**", "identical_positions": 238, "similar_positions": 46, "identity": "73.91%" }, { "cls_id": "homologset.agr.HGNC:3382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AT61-1", "uniprot_id": "A0A8I6AT61_RAT", "id": "A0A8I6AT61-1", "name": "Dematin", "aln": "MERLQKQPLTSPGSVSSSRDSSVPGSPS-NIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRECSLSPKSTSPPPSPEV--------WAESRTLG---IISQASTPRTTGTPRTSLPHFHHPETTRPDSNIYKKPPIYKQRESVGGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRKGAEEEEEEEDDDSEEEIKAIRERQKEELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLHSGTSKSSSLPSYGRTTLSRLQSTEFSPSGSEAGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV69-1", "uniprot_id": "DEMA_MOUSE", "id": "Q9WV69-1", "name": "Dematin", "aln": "MERLQKQPLTSPGSVSSSRDSSVPGSPS-SIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRECSLSPKSTSPPPSPEV--------WAESRTLG---IISQASTPRTTGTPRTSLPHFHHPETTRPDSNIYKKPPIYKQRESVGGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRKGAEEEEEEEDDDSEEEIKAIRERQKEELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLHSGTSKSSSLPSYGRTTLSRLQSTEFSPSGSEAGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08495-1", "uniprot_id": "DEMA_HUMAN", "id": "Q08495-1", "name": "Dematin", "aln": "MERLQKQPLTSPGSVSPSRDSSVPGSPS-SIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEV--------WADSRSPG---IISQASAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRRGAEEEEEEEDDDSGEEMKALRERQREELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLHQGTSKSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E6V5-1", "uniprot_id": "A0AB40E6V5_DANRE", "id": "A0AB40E6V5-1", "name": "", "aln": "--------MQKAGTAPSSRGPSAPGSPATSIVARMDNQVIGYKDLAAIPKDKAILEVERPDLMVYEPHFNMAALDHVGLSRSRERSMSPHSISPPPSPEISASKELKDWSEQGSPGGSNMGSTTQLRKISPASKGPMQHFHRPDS---GINLYKKPPIYKN-ERQTGAPHSK---QDLIIVSSKFPAAQPPDPSLPSKIETEYWPCPPSLATMEIEWR-----RKAAEQGKPMEDDDFEDLTEDAKRLQEQELQKIQSNLGKLILKEEIEKSGLIRRKTRSLPDGTNIHLGSSASTTKSASLPPCSRTGLTRLQSADFSSTDNGKAKTGVPNGDSQSGRMDRGNSLPSILEQKIYPYEMLIVTHRGRTKLPPGVDRTRLERHLSPEEFHSLFGMPITEFDRLSLWKRNDMKKKVSLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..*:...**..*.****: .***:*****:***************::******:*****. : *:** *.**** *:**:* *******: *::. : * : * :. : : :.: .: ***:*:: . *:********: * *:*::* :**** ************. *:****:*********.:* *** *:.**: : **** : : :. *.:**.*: *****:*****:*** ********** * :* . .*:**:***. .** *:****::**.:.. ...*: **:.* **********.:***********:**::*********** *******.*:* :*.*. **.:*:*****::***.***", "identical_positions": 229, "similar_positions": 103, "identity": "54.92%" }, { "cls_id": "homologset.agr.HGNC:33821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LIC3-1", "uniprot_id": "A0ABK0LIC3_RAT", "id": "A0ABK0LIC3-1", "name": "", "aln": "MTSPATTLFGMSSPALANPRKHQEPGVRPASVTAALPSTLELLKDVHLGLAVPCQDPARLALLSGHYLYYHYGCDGLDDRGWGCGYRTLQTLCSWPE---GQSSGVPGLAALQGALEDMGDKPPGFRGSRNWIGCVEASLCLEHFGGPQGRLYHLPRGAELRGELERLYSHFTAGGGPVMVGGDADAQSKALLGICEGPDMEVYVLILDPHYWGTPKNRCELQAAGWVGWQKALPPTADKSLSASKVWVRHDGRAGESEFRVNLVYPTSSRSAGVKTLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZP0-1", "uniprot_id": "UFSP1_MOUSE", "id": "Q9CZP0-1", "name": "Ufm1-specific protease 1", "aln": "-------------------------------MTAALPSTLELLKDVHLGLPVPCHDPARLALLSGHYLYYHYGCDGLDDRGWGCGYRTLQTLCSWPG---GQSSGVPGLPALQGALEAMGDKPPGFRGSRNWIGCVEASLCLEHFGGPQGRLCHLPRGVGLRGEEERLYSHFTTGGGPVMVGGDADAQSKALLGICEGPGSEVYVLILDPHYWGTPKNRCELQAAGWVGWQKVKSVFDSNSFYN-------------LCFTRNL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NVU6-1", "uniprot_id": "UFSP1_HUMAN", "id": "Q6NVU6-1", "name": "Ufm1-specific protease 1", "aln": "---------------------------------------MEPLRDVHVGLSPPSRGPVRLALLSGHYLYYHYGCDGLDDRGWGCGYRTLQTLCSWPE---GQPAGVPGLAAVQAALEDMGDKPPGFRGSRDWIGCVEASLCLAHFGGPQGRLCHVPRGVGLHGELERLYSHFAGGGGPVMVGGDADARSKALLGVCVGSGTEAYVLVLDPHYWGTPKSPSELQAAGWVGWQEVSAAFDPNSFYN-------------LCLTS-LSSQQQQRTLD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V6M7-1", "uniprot_id": "UFSP1_DROME", "id": "Q4V6M7-1", "name": "Probable Ufm1-specific protease 1", "aln": "-------------MAAEKCAEEFGDSSAASLKIVPKDYAYPLLEDPQGALTTPTEG-GRTLVTRGGFNYFHYGCDGHQDAGWGCGYRTLQSAISWIQRRQGSSGHVPSIREIQQILVAIGDKGPEFVGSRDWIGTLEEFYVIDVLHQVPCKILHA-KELSSDEILGELRSYFEKYQGFVAMGGLSDTASKAITGYHCSARGRIFLQVVDPHFVGVPSSRQHLIDLGYVRWVPVDEFAG--STYN-------------LCLILQP---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* : .*. * .. * : * : *:****** :* **********: ** *... **.: :* * :*** * * ***:*** :* : : :: * : .* *:* * * :** :*: ***: * .. . :: ::***: *.*.. .* *:* * . * : ", "identical_positions": 66, "similar_positions": 46, "identity": "23.66%" }, { "cls_id": "homologset.agr.HGNC:33823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5G5D5-1", "uniprot_id": "SYNA_MOUSE", "id": "Q5G5D5-1", "name": "Syncytin-A", "aln": "MVRPWVFCLLLFPCSSAYSDSWMPLVNLTQHLLQEANSSFSSNCWVCLSIQTQRS-LAMPAPLRTWTETPMKLRIMYSARTLSGPYPITDLERRLQNFQPLTPHSSFVNPDQRAIAFLQITSVTGILPILSRITSVRYPD-DHVYESAQRPIWGSLSTQTILTSQAPLCISRFFKNSNHATFVGKLPASLCNHTFQLSPSANHQSIDLSSSYAFAPLMAMPGSKWRNPLRFSGPPSLNSGMP-HYSCPIDDIHCHTYPTTPWRSCPSFP-ASTCYNLTLFEPDNSSHPITLSVDTTYFKIKLQGHKDPYPLFQYQPLMGAALSGQYSIWEYEPTVKKNGGITPNIFSHLVSLTYSFCLNSSGVFFLCGNSTYVCLPANWSGVCTLVFQYPDIELLPNNQTISVPLFATVPSSVPASRRKRALPLLPLLAGLGIASALGLGIAGITTSTVYFQQLSKALSDSLDEIATSIISLQDQIDSLAGVVLQNRRALDLIVAERGGTCLFLQEECCFYINQSGVVRHAARKLRERASELGTSSSS-WIQWLGLGPWLPSWLTSLMAPILFILVLLVFRPCLLNCLTHSVSRRMSSFIHTTTEGHVDKILLLRESQYKRLPQEPPEEDAV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5G5D4-1", "uniprot_id": "Q5G5D4_RAT", "id": "Q5G5D4-1", "name": "", "aln": "MVRPWVFCVLLFPCSSAHSDSWMPLVNLTQRLLRDANSSFSSNCWVCLSIQTQRS-LAVPAPLRSWTETPMKLRIMYSARTLSGSYPITDLERRLQNFQPLTPHYSFVNPDRRAIAFLQVTSITGILPILSRLTPVKYPN-DRFYESAQRPIWGSLSTQTILTAQAPLCISRFFKNSKYATFVGNLSASLCNHTFQLSPSANHQSIDLSTSYAFAPLMAMPGLKWRNPLHFSGPPSLNSGKP-HHSCPVDDIHCHTYPTTPWRYCPSFLSSSTCYNLTLFEPNNVSHPITLSVDTTYFKIKLQGHKDPYPLFQYQPLMGAALSGQYSIWENEPNVQENGGLTPNIFSHLVSLTYSFCLNSSGVFFLCGNSTYVCLPANWSGVCTLVFQYPDIELLPNNQSIMVPLFATVPSSVPASRRKRALHLLPLAAGLGIASALGLGAAGIATSTMYFQKLSKALSNSLDEVATSILSLQDQIDSLAGVVLQNRRALDLLVAEKGGTCLFLQEECCFYINQSGVVRYAARKLRERASELGPSSRS-WIQQLGLGPWLPSWLTSFMGPILFILVVLVLGPCLLNCLTHSVSRRMSSFIHTTTKGHVDKILLHRETQYKRLPQEPQEEDSV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BI41-1", "uniprot_id": "SYNB_MOUSE", "id": "Q8BI41-1", "name": "Syncytin-B", "aln": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRS-LAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAP-FGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDS-WGQWPDLGRWLP-WLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQN--FQYKKLPQDSPDEDTIPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A443-1", "uniprot_id": "A0A8I6A443_RAT", "id": "A0A8I6A443-1", "name": "", "aln": "MTHLWVLCFVLFPSSLSYPESWMPLINLTHHILRDANSSLFPNCWVCLSTQTQRS-LAVPAPLSTWTDTPMKLHLTYSVKAFPGSFPISDLERRLRLFHPLIASYPFHNPERRAITFLQLVSSTGIFRIITRITSVIYPEKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTLRISPSTSHENLDLSITHPFKQAMKRPNAKWKNPLRFSGPPSLIFSKPSYHPCPAD-KYCHTSPATPWMRCPHAP-SSTCYNLTLFESDNLTHPVTMSVDSTHFKAKLQGRRDPYPLSHYQPIPGAALSGQYSVWENEITIQENWGVTSNIFSHLLSFSYIFCLNSSGVFFLCGTSTYVCLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSASVLRPKRSPHLLPFLAGLGISSALGTGIAGLASSTLYFQRLSKALSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLRERASELSQHSDS-WGQWPDPGRWLP-WLTPFLGPLLFIFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKMQVDSILQN--FQYKKLPQDSQDEDTIPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60508-1", "uniprot_id": "SYCY2_HUMAN", "id": "P60508-1", "name": "Syncytin-2", "aln": "-MGLLLLVLILTPSLAAYRHPDFPLLEKAQQLLQSTGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPN--------LKGLMRPANSLLSTVKQDFPDIR----------------------------------QKPPIFGPIFTNINLMGIAPICVMAKRKN---GTNVGTLPSTVCNVTFTVDSNQ-------------QTYQTYTHNQFRHQPRFPKPPNITFPQGTLLDKSSRFCQGRPSSCSTRNFWFRPADYNQCLQISNLSSTAEWVLLDQTRNSLFWENKTKG-ANQSQTPCVQVLAGMTIATSY------LGISAVSEFFGTSLTPLFHFHISTCLKTQGAFYICGQSIHQCLPSNWTGTCTIGYVTPDIFIAPGNLSLPIPIYG----NSPLPRVRRAIHFIPLLAGLGILAGTGTGIAGITKASLTYSQLSKEIANNIDTMAKALTTMQEQIDSLAAVVLQNRRGLDMLTAAQGGICLALDEKCCFWVNQSGKVQDNIRQLLNQASSLRERATQGWLNWEGTWKWFS-WVLPLTGPLVSLLLLLLFGPCLLNLITQFVSSRLQAIKLQTN------------LSAGRHPRNIQESPF---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:* *. :: .. :**:: ::::*:.:.*. .***:* * .*: . * **. **. :*:: * . :: :: ..* . *: * : *::*.: *: * . **:*: * .* **.*.:::** *: :... . :::: :*. **.: . :. . :. . * ::: :.. : : :. .:: * :* : * : * ::: .* :. . . :: *. : **::.*.*::** * : ***:**:*.**: : *** : *.* :: :*::. . . * :*: ::*: ***** :. * * **::.::: :.:*** :::.:: :* :: ::*:******.*******.**::.* :** ** *:*:***::**** *: *:* ::**.* : . * : . *:. *: .: .*:: ::.:* : .**** :*: ** *: :: * . : *:: :. ", "identical_positions": 135, "similar_positions": 198, "identity": "21.63%" }, { "cls_id": "homologset.agr.HGNC:33825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IE38-1", "uniprot_id": "ISK14_HUMAN", "id": "Q6IE38-1", "name": "Serine protease inhibitor Kazal-type 14", "aln": "MAKSFPV-FSLLSFILIHLVLSSVSGPRHWWPPRGIIKVKCPYEKVNLSWYNGTVNPCPGLYQPICGTNFITYDNPCIL-CVES-LKSHGR-IRFYHDGKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IE46-1", "uniprot_id": "ISK14_RAT", "id": "Q6IE46-1", "name": "Serine protease inhibitor Kazal-type 14", "aln": "MVKYFQVLWSLLFSIMLHSMLLAAPGARVWWPTHGLIKIKCPYKKVKLSWFNKTVDPCPGLKQPICGTNFVTYDNPCIL-CVES-LKSGGQ-IRYYHTGRC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PBA3-1", "uniprot_id": "M9PBA3_DROME", "id": "M9PBA3-1", "name": "Kazal-like domain-containing protein", "aln": "--------MKFLSILVALCLLLALT----------ISPISCDDTEKVV----RPICPCPRNYEPVCGSNLVTYPNRCEFDCVRRNVERQGRSMGLLRDGTC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* :: :* : . : :.* : : .: *** :*:**:*::** * * : **. :: *: : : * *", "identical_positions": 19, "similar_positions": 26, "identity": "18.81%" }, { "cls_id": "homologset.agr.HGNC:33826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q642A4-1", "uniprot_id": "CH082_RAT", "id": "Q642A4-1", "name": "UPF0598 protein C8orf82 homolog", "aln": "-MWPPCGAMRNLALVLARSQRARACSGNERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPN---SPTVPSHVQWQGRRIALTMDLAP---LLLAAPPP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE95-1", "uniprot_id": "CH082_MOUSE", "id": "Q8VE95-1", "name": "UPF0598 protein C8orf82 homolog", "aln": "-MWPPSGAVRNLALVLARSQRARTCSGVERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPS---SPTVPSHVHWQGRRIALTMDLAP---LLPAAPPP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1X6-1", "uniprot_id": "CH082_HUMAN", "id": "Q6P1X6-1", "name": "UPF0598 protein C8orf82", "aln": "-MWPPCGTLR--TLALARSRGARACSGDGGVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDPQFLVTFFSRLRPNRSGRYEAAFPFLSPCGRERNFLRCEDRPVVFTHLLTADHGPPRLSYCGGGEALAVPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPG---APALPSHVRWQGRRLALTMDLAP---LLLAARSP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JMG6-1", "uniprot_id": "B8JMG6_DANRE", "id": "B8JMG6-1", "name": "", "aln": "--------MRFVKRIFSR-QCGLFCRNVS--SYTQGQSPEARIREYFYYIDHQGQLFLDDTKVKNFVTCFKDQHFLVFFFSRLKVNQSGRYQQDFPFVSLCGRERNFLRCEDQPIVFTHLFSEVGLEDRLSYCGGGAKLSVPFRPQSLFMHPDSGRVYHPGPERTGGAGLLRSALAIEISAHFGYDTGQDGTAAQPTHFTWAGRRHALSKELEK---HFPVQKDECMKIR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MKL1-1", "uniprot_id": "U598_DROME", "id": "Q8MKL1-1", "name": "UPF0598 protein CG30010", "aln": "MFILRSRSLTNLKFVRSP---SISCRYVQ---YNQGQSPEPKIREYFYYIDHEGMLFLDDAKMKNFTSCFKEKDFLKFFFNRLRLNKTSRYESEFPYISLCGRERNFIRCDDTPVVFTEQLRKDD-TEVLSYAHAGQVLTLPYEPHKLYMDPRNGRVYHPAAPQVGGIGLVRSKLAIELSQHFEFLAG----EASPTHFQWNGERLELQNEWVNNTQRFPMNEDCK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * *.******.: ******:**:* *****:*:*** :***: .** **.**: *::.**: **::* *******:**:* *:***. : ***. .* *::*:.* * . .**:***.. :.** **:** **:*:* * : .. : *:*. * *.* * : : ", "identical_positions": 85, "similar_positions": 51, "identity": "36.96%" }, { "cls_id": "homologset.agr.HGNC:33829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZR37-1", "uniprot_id": "PKHG7_HUMAN", "id": "Q6ZR37-1", "name": "Pleckstrin homology domain-containing family G member 7", "aln": "---------------------------------------MEKTESFCPEVPPQDCG----------ASPRPSLRSLPKN---QGSLL--QFDRQAPGRISTSPTLRR----LRTRGCGTRQDAWQVTT---WGSWGAPVGFPCYLSKSLPGSPKDSSHLLSPLRLHSRLTSEPERALN--AADSLEPQT---RPTDKYLPPELQPVNEGSLHQASLRQQEGHFLPSPTLRHPSPQGEELHPS-------------------RFYEHRRSSVVLNLPGLEVFPGDLLVSDGAADYLCHPLLLLNSESKKPRWPFSKRGVG-KDKHKHISDLENCLSSVKITSFRGYDFYGLKDKTWDEVLETHHKLPTDQLDLK-KQQEAVWELFTSECTYFLDHLLVLKMIFMNTLRYLQTHEYLLDVDLWRLFANLEELTQTSLGFVNSLFGIIKDYVDASEISSSLDFISVLTKYFRGSLCQSHQTYCLNYSAAIFYLESLRQRDDFGIYLKWCEQNEQCRRLHVPELLVAPLQRLTRYPLLLKNIWKRSMDSAEKIMIYSIKEKVEKSIRDLEGKVKWLDNFQKFRYLQEIIVWPPLWDRDKRFFIPECLKHIFKEHMAENILSPTSRHLLYEGKLTLAESTRFLDVYLFLFNDFLLVTKTKCNKKKLGGSDPGLMCPSLTPELQAVIKEGGSCTVLDQPIPLDRLVVKSIEPLHVSVFGLRNAFLIQHENRYRQCIAAFLLQAQTENIKKTWMAQITTAISCFTKSQETK-KISLFTLPAESSEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8HAL3-1", "uniprot_id": "A8HAL3_DANRE", "id": "A8HAL3-1", "name": "", "aln": "MTELNYAFISENRKEVDKSLDWSYIDWHDKKMVKGTDAQTQTQHVHSKDIDTQTTNPCTMRINFDSTSSGMKLGSVTTSNCTSGDLITQEIHRHSPAPISPSQTQRRMPLPLHTPNFHRHSPACCSTSPALWRSSGMSYSVDFHRHSPTRISTSPTLRRMRSTRIYNRETSNPAKPLREESSTPMSPHSSFFREKSPLAADEENKSPESSVTPGTVRTHRSQTLDNGSICKSKESCDSKKPASDKESTTDDNEQVKDPCHKRLKERRRSSVVVSLPGLDVSPGDLFVSNGAADMLNK----SDYSEKKSKWPFSRRSTQTKVKTRSGADIDKCLASVQVPEWRDTDFQTFKDMSLVDFLQGRSELKAAQHPMTYKTQEAIWELFTSECVYFLDQLMVLKEVFLTTLSDLQTRQCLQDIDSWRLFANLNELCLVSFGFLTSLLRVIKEMWTDPDSCSTQSLHDLFRKAFSESICHCLQKYCLNYSTAILYLDSLKLREDFGSFVKWCERNEECRRLQLKDLLVVPLQRFTRYPLLLKNIGKRSCSKAEENTIQSIVDLVDRAIYDLEGKVKWLDNYQKVKQLKETLVWLPVWESDKRAHVPESLKHLLKPVTLENLVIN--RSLLHDGKLFLIENTKQQEVYLFLFDEFLLITKIKRNKK----QKSGVVDFAAGQELELLLQEGCSFTVLDQPISLDRLQLKNIDQLNATASTLPNSFIIMHQNRYQQCIAVFVLQAQSESTKKAWMSEIEKAVSSLLKQDSLHPRVNNSFHYTESSQI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . .. :: .* . :*. .* *:... .*.*: ::.*::*. **.* * ** *:* . :. * *: * * * . .. : .. *.. : : : . *::.* **:* :.*. :: .:.*:: * .. . * : *.*: .::* :..: * . :: :.. . :. :*: *: *:******:.****:* ****:**:**** * : : ..**.:****:*.. * * : :*:::**:**::..:*. ** :** : :.*: : :* : * :. * ***:********.****:*:*** :*:.** ***:: * *:* *******:** .*:**:.**: :**: .: .*: .: .:: * * *:*:. *.******:**:**:**: *:*** ::****:**:****:: :***.****:********** *** ..**: * ** : *:::* ***********:**.: *:* :** *:*: *** .:**.***::* **:: * **::*** * *.*: :******::***:** * *** ...*:: : **: :::** * *******.**** :*.*: *:.:. * *:*:* *:***:****.*:****:*. **:**::* .*:*.: *.:. : ::. :***:*", "identical_positions": 290, "similar_positions": 235, "identity": "37.23%" }, { "cls_id": "homologset.agr.HGNC:3383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZV26-1", "uniprot_id": "A0A8I5ZV26_RAT", "id": "A0A8I5ZV26-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------CVRRRQGNSGKASCVALFLTD-------------NSKAELGPCGWILVAVSFIFVLITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIMGSHH-----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54116-1", "uniprot_id": "STOM_MOUSE", "id": "P54116-1", "name": "Stomatin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MSDKRQSSHVQSQRIPESFRE-------------NSKTELGACGWILVAASFFFVIITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILPCTDSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPVDMLQGIMGSNH-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27105-1", "uniprot_id": "STOM_HUMAN", "id": "P27105-1", "name": "Stomatin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MAEKRHTRDSEAQRLPDSFKD-------------SPSKGLGPCGWILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIIGAKHSHLG-------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IGK4-1", "uniprot_id": "A0A0R4IGK4_DANRE", "id": "A0A0R4IGK4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------MEDGRETAAMREEERRKRQIDSELSSRNNKDQWCHTVDDSQALENTDSDIGLCGWILVIFSILLTLLTLPLSIWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFILPCTDSFINVDMRTITFDIPPQEVLTKDSVTVSVDGVVYYRVQNATLAVANITNADAATRLLAQTTLRNVLGTKNLAEILSDREEIAHSMQSTLDDATDDWGIKVERVEIKDVKLPLQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIIFPLPIDMMQSFL--KH-----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZA4-1", "uniprot_id": "BND7A_DROME", "id": "Q9VZA4-1", "name": "Band 7 protein CG42540", "aln": "MPDSMMDMEHRDHQLHRQQQQSHHHQPPRLTASTSTFAPPAPAGSQSEERDRDRDRERDHHLHHHQSNNVASSPLPVTASIQLHQQQPQQQQQQQPLTQLQQPQLREREHHQQQQQQQQQMMQQPQQQQQMQQPQQQLPHSHHALMQQSQQQQAIHRAEARRADEEISDKASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQVQLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFLKTNEATTQQNARAAAAAIGNTPPPLQLAPQQQMGQQQQPQYQQPQQQQQQYQPQQQQQQQQQQPQQQDQLYQQGQQISSAM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: . : . . . ** :*: *. :.::*:*:*:::*:*:::****.:******:::*******:****** ** .**:** ::*:****:*******:***.******.***:::**: **. :***********.:**::* :***:* *: ** **:*** *************:**:************:************* :*****:*** ** :**:**********.**:*******:****:*:: :: :. ", "identical_positions": 168, "similar_positions": 70, "identity": "33.27%" }, { "cls_id": "homologset.agr.HGNC:33830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZ71-1", "uniprot_id": "A0A8I5ZZ71_RAT", "id": "A0A8I5ZZ71-1", "name": "", "aln": "MASGSGAG---AAASANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEALSSVIKELRKGT--EALKAAENTS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUR9-1", "uniprot_id": "MZT1_MOUSE", "id": "Q8BUR9-1", "name": "Mitotic-spindle organizing protein 1", "aln": "MASGSGPG---AAASANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEALSSVIKELRKGT--EALKAAENTS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08AG7-1", "uniprot_id": "MZT1_HUMAN", "id": "Q08AG7-1", "name": "Mitotic-spindle organizing protein 1", "aln": "MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEALSSVIKELRKAT--EALKAAENMTS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C8Y1-1", "uniprot_id": "MZT1_DANRE", "id": "P0C8Y1-1", "name": "Mitotic-spindle organizing protein 1", "aln": "MAS---------PASANMNAVRETMDVLLEISRLLNTGLDMESLSICVRLCEQGINPEALSSVIKELRRAS--DSLKASENSTSQG-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6ILY6-1", "uniprot_id": "Q6ILY6_DROME", "id": "Q6ILY6-1", "name": "", "aln": "-----------MSEQPTQHKSDDRFTILQTLSDVVDSGLSKEALKICIELVDNGVCGGALAHVIRTIREEIQDDEDKESDDSGESAASTDSTL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. : : : :* :* ::::**. *:*.**:.* ::*: **: **: :*. : * ::: ", "identical_positions": 16, "similar_positions": 28, "identity": "17.2%" }, { "cls_id": "homologset.agr.HGNC:33834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FJQ8-1", "uniprot_id": "F7FJQ8_RAT", "id": "F7FJQ8-1", "name": "", "aln": "MDLQRPHRELRRKHRKQPSLQSKLNPLLPPTMYCNCFSEGIRAAPVNYWISGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVADCPPWKVWTPSTPCLLLRPPALCQTALVPVAEQSEPLRSMLCT-RATGTQPARERTPPQPPEASGDKDSSSFS--SFGSVLGPGWQNPCCCFWNHQGDLPSFASFAP--VPCLCCNWAHLSGPILPPLSSEQPLLESLKPGPRLPGPMWMPGAWHFPGLHLLARLRQGT---------EAPEVPQAPGIG----------------------GKSWPRAKQAPGFQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A5F8MPE2-1", "uniprot_id": "A0A5F8MPE2_MOUSE", "id": "A0A5F8MPE2-1", "name": "", "aln": "-------------------------------MYCNCFSEGILAAPVNHWVSGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKKFTYKFNFSKLMVANCPPWKVWAPPSPRLLLRSPALCQP-LVPMAKQSEPLYSMLCT-RATETQPAGERTPQRPPKASGDKESSSFNCECFGSVLGPGWQRPCCCLRNLQGGLPSPAPLAS--VPCLCCNWTHLLGPILPPLPSEQSLSGSSKPGPRLSGPMCMPGTWHFPGLHLLARLRQNTGQGLWCQFLRPEELVVNPGPGPSRH--LDSNEGLSSGTQGLKLGKGISMSPNPENMRVMWPSDPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZN32-1", "uniprot_id": "ETV3L_HUMAN", "id": "Q6ZN32-1", "name": "ETS translocation variant 3-like protein", "aln": "-------------------------------MHCSCLAEGIPANPGN-WISGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVVNYPLWEVRAPPSPHLLLGAPALCRPALVPVGVQSELLHSMLFAHQAMVEQLTGQQTPRGPPETSGDKKGSSSSVYRLGSAPGPCRLGLCCHLGSVQGELPGVASFTPPLPPPLPSNWTCLSGPFLPPLPSEQQLPGAFKPDILLPGPRSLPGAWHFPGLPLLAGLGQGAGERLWLLSLRPEGLEVKPAPMMEAKGGLDPREVFCPETRRLKTGEESLTSPNLENLKAVWPLDPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.*::*** * * * *:***********************************************************************************************:**********:*.: * *:* :*.:* *** .****:. ***:. *** * *** : :* * : ::** **::****..** . :**. ** ** : . ** **. *.::. * * .**: * **:****.*** * : **. *.** :**:****** *** * *.: .. : *. *: : : .:: ", "identical_positions": 196, "similar_positions": 58, "identity": "49.87%" }, { "cls_id": "homologset.agr.HGNC:33842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZF7-1", "uniprot_id": "AARD_RAT", "id": "Q91ZF7-1", "name": "Alanine- and arginine-rich domain-containing protein", "aln": "MGLGDYSHCRQRMSRGLYGVSGRATLWSPAFHPVHRMPCGTWRI--EAPEHVRASSPVLEHLRRQLERAFQRAAARGRARRAREAVAAVAAAAAAAREERSRARMECALARLRAELLELRFQNHQLARTLLDLNMKMQQLKKRQDQERASKPQSPQDEEMNPECGNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q811W1-1", "uniprot_id": "AARD_MOUSE", "id": "Q811W1-1", "name": "Alanine- and arginine-rich domain-containing protein", "aln": "MGLGDYSHCRQRMSRGLYGVSGRAALWSPVFHPVHRMPCGTWRIGIEVPEHVRASSPVLEHLRRQLERAFQRAAARGRARRAREAVAAVAAAAAAAREERSRTRMECALARLRAELLELRFQNHQLARTLLDLNMKMQQLKKRQDQELASKPQSPQDKEMNSECGSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4LEZ3-1", "uniprot_id": "AARD_HUMAN", "id": "Q4LEZ3-1", "name": "Alanine- and arginine-rich domain-containing protein", "aln": "MGPGDFRRCRERISQGLQGLPGRAELWFPP-RPACDF-FGDGRS-TDIQEEALAASPLLEDLRRRLTRAFQWAVQRAISRRVQEA-----AAAAAAREEQSWTGVEATLARLRAELVEMHFQNHQLARTLLDLNMKVQQLKKEYELEITSDSQSPKDDAANPE----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **: :**:*:*:** *:.*** ** * :*. : * * : *.. *:**:**.***:* **** *. *. :**.:** *********:* : :*.:********:*::****************:*****. : * :*..***:*. *.* ", "identical_positions": 89, "similar_positions": 39, "identity": "53.29%" }, { "cls_id": "homologset.agr.HGNC:33843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z6K4-1", "uniprot_id": "NRARP_HUMAN", "id": "Q7Z6K4-1", "name": "Notch-regulated ankyrin repeat-containing protein", "aln": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTN-----CEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANR---DGWSALHIAA--------------------------------------FGGHQDIVLYLITKAKYAASGR---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9S9-1", "uniprot_id": "D3Z9S9_RAT", "id": "D3Z9S9-1", "name": "", "aln": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTN-----CEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANR---DGWSALHIAA--------------------------------------FGGHQDIVLYLITKAKYAASGR---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZA8-1", "uniprot_id": "NRARP_MOUSE", "id": "Q91ZA8-1", "name": "Notch-regulated ankyrin repeat-containing protein", "aln": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTN-----CEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANR---DGWSALHIAA--------------------------------------FGGHQDIVLYLITKAKYAASGR---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7T3Y0-1", "uniprot_id": "NARPA_DANRE", "id": "Q7T3Y0-1", "name": "Notch-regulated ankyrin repeat-containing protein A", "aln": "MSQADISTCSAP--QRVFQEAVKKGNTKELHSLLQNMTN-----CEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANR---EGWSALHIAA--------------------------------------FGGHQDIVLYLITKAKYSSGAR---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T3X9-1", "uniprot_id": "NARPB_DANRE", "id": "Q7T3X9-1", "name": "Notch-regulated ankyrin repeat-containing protein B", "aln": "MSQADM-TCSAR--QRVFQEALRKGNTKELHSLLQNMTN-----CEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADTRLANR---DGWSALHIAA--------------------------------------FGGHQDIVLYLITRAKYSSSAL---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53066-1", "uniprot_id": "YGZ2_YEAST", "id": "P53066-1", "name": "Ankyrin repeat-containing protein YGL242C", "aln": "-----MNTEGASLSEQLLDAARRN-NLDLLETVFDSLDNDPEKIAKLINESKEPLGNTALHLCCKYGSWEVLDKILDQDGEIEIDPQNDVDGDTPLHVTVRYSQEEPEHGTFIARNLIEVGADPRVRNYNNQKPVDLVHGDELDELIDLLQGAELAIDSTNGSGDNNEDGEMIDDGPSDDDEEDDKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .* ::::: * :: * . *.::::.: * .:: :* * *:**** . *. *::. ::. ..: .: : :* :.**::. .*.. * :: *: *: : .. ", "identical_positions": 22, "similar_positions": 52, "identity": "11.76%" }, { "cls_id": "homologset.agr.HGNC:33844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IA44-1", "uniprot_id": "GLT12_DROME", "id": "Q8IA44-1", "name": "Putative inactive polypeptide N-acetylgalactosaminyltransferase 12", "aln": "---------MEVFASVLNCCFKYIVLPVWIFIV--------------------------------------------------------------------------------------------LLLLHRDLSSWDGLMGPLSHPGLGENGSASYLSVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVND-HSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAY-QRSIE-RRGMYDWSLTRREVPLSRARRSH-LPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQ--KSRNLKRIIEVWTGDLKSAIYKYQP-HLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLN-HVAALNRTDYASGHVKTLEFPKKCLTINAKSQNLFLERCSTNNT---LQN-----WTLTYVKDLR--------VAGNICAEVRPNLRLGYSFCHSLGGRQSWHYDSVSNQLMSN-----TKCLEFTD----ELNIFLAICDAANGKQRWILDNIN---LSVMQSANILV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IA41-1", "uniprot_id": "GLT11_DROME", "id": "Q8IA41-1", "name": "Putative inactive polypeptide N-acetylgalactosaminyltransferase 11", "aln": "-------MKSLLFGTPCSCAIFILVYCIITLFI--------------------------------------------------------------------------------------------WFLYTDNLSNAIVDFEYFSIKNLGELGKEAHLQMTETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYS--SEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIR-----------HIHHKLPIVIQLEMESSKGIIHARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAY-RKLVEPEQLAFDWQLDHIFLPLDQHSWNS-LPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDE-LEAQMAPNRNPSLQ--VQKNFKRVVDVWLDEYKLHFYRYNP-KLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAPHFCLSIKG---GFPVIRKCHSTN---FED-----WTLTSRCQLK--------HG-NMCLDVDYKNNVRATKCTKKLSKNPWHYNYQHSSFVSNG----NKCLQIDVN---KVGLILSACDSDVTEQRWMFTKVQDFKLDHMRDICLSVNH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUT6-1", "uniprot_id": "GALT8_DROME", "id": "Q9VUT6-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 8", "aln": "MCLDIWRHKKKVLPLLLLMAIGSIIYYLYTLKLEGERDESATST---------------------------------------------------------------------------------TSRLERDIRDLQAVFESEVIPDLGALGRPARGNWTEEQLEAIAKSQRETGYNAWLSKRISPERSLYDMRHRSCKKLKYP--MEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQADEKLN--------DFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAY-RRGKP-SRGFFNWEFNYIQLPLLKEEAVA-MPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGN-FQIRYTNKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMP-HLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYASGVLQSISSPKLCLDRKDPSHGQPKLAPCSSDH---VFPSPEQYWSLTNHRELR--------SGFYCLEVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNFRHCLEAQPE---LNAVTSSVCDPKNHKQQWKFGYLNSQRLQHFWDNVKTQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q49A17-1", "uniprot_id": "GLTL6_HUMAN", "id": "Q49A17-1", "name": "Polypeptide N-acetylgalactosaminyltransferase-like 6", "aln": "---MKR-KQKRFLQMTLLFTVALIFLPNVGLWS---LYKDKHLVKSAE-------------------------------------------------------PGEQQTFPLGLGD--GQFYSWTDGLRRKDWHDYESIQKEAMRSGKGEHGKPYPLTEEDHDDSAYR----ENGFNIFVSNNIALERSLPDIRHANCKHKMYL---ERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDDFSEREHLKDK------LEEYMAR-FSKVR-IVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYV------PYKVPS--GTSLARNLKRVAETWMDEFAEYIYQRRP-EYRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYPPVEPPPAAWGEIRNVA-ANLCVDSKHGATGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNS--PVTLYDCHGMKGNQLWGYR-KDRTLFHPVSN-SCMDCNPAE----KKIFMAR-CDPLSETQQWIFEHINMTVLEKFNHHANS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZYW6-1", "uniprot_id": "A0A8I5ZYW6_RAT", "id": "A0A8I5ZYW6-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "---MKR-KQKRFLQMTLLFTVALIFLPNIGLWS---LYKDKHLMKSAE-------------------------------------------------------PAEHQTFPLGLGD--GQFYSWTDGLRRKDWHDYVSIQKDALRSGKGEHGKPYPLTEEDHDDSAYR----ENGFNIFVSNNIALERSLPDIRHANCKHKMYL---ERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHLKDK------LEDYMAR-FPIVR-IVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHSHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYV------PYKVPS--GTSLARNLKRVAETWMDEFAEYIYQRRP-EYRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYPPVEPLPAAWGEIRNVA-ANLCVDSKHGAMGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCLDAISHSS--PVTLYDCHGMKGNQLWGYR-EDRTLFHPVSN-SCMDCNPAE----KKVFMAR-CDPLSETQQWMFEHINMTVLEKISHYAIS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6WV16-1", "uniprot_id": "GALT6_DROME", "id": "Q6WV16-1", "name": "N-acetylgalactosaminyltransferase 6", "aln": "---MRRPNLKWIVKASLLLLISLTLFVLITSWISSTPYTNKPVHHGVEPVPEKAGLSGDVKVKVPAIKQPEPQKPQEPDFEEDPELQKIDEPEPVEEEVDNPHPADDEPQQQPQEE--LQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRM-SLENGFNALLSDSISVNRSVPDIRHPLCRKKEYV---AKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKE------LETYIAEHFKWVR-VVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQD-EGARGAFDWEFFYKRLPLLPEDLKH-PADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPR------NHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADN--IKTPQRTQFWELSWKRDLR----LRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFS----QEVVANK-CDTDNRFQQWNFGSFNKTALDNYSQDLVLSL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IA42-1", "uniprot_id": "GALT4_DROME", "id": "Q8IA42-1", "name": "N-acetylgalactosaminyltransferase 4", "aln": "-MAIKKRYVKRLLRKVVLLLVVIVTVSLVTTLVVERRMKNAAELTEQLD----------------------------PNGDPITPVFRAANIHPTRKAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEH-YEMNGFNGLISDRISVNRSVPDLRLEACKTRKYL---AKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQP------LDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALD-KSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPM------KPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADN--RTHPQPNQFWELSIFRDLR---MKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLEGFVENG--IAKVVANS-CENGNDRQRWEFGFVNHTMLDTFYDGLK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IA43-1", "uniprot_id": "GLT10_DROME", "id": "Q8IA43-1", "name": "Putative polypeptide N-acetylgalactosaminyltransferase 10", "aln": "---MNVDLRLIVRLLLAILLTSLVTTILMGKQIHRRLVKSMVKTTGEKD-------------------------------SLPARQLPKREISPKVADFPPPLTLNQTELDILKIQRNNSFRLPQQE-AIKEWQDAIFFKEDSNRRGLGEQGRAVQLPNAKLNPDDFQ------DFYAELSDRIPLNRSLPDTRPISCRKRKYL---ENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQIVLVDDDSNLPELGQQ------LEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEVNTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQN-TMTRSGFNWWLESESLPIFPEDKSP-DSTPYRTPVLSG-AMAIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHIGKRPM------KSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALECKTFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLARCTGH--NSMPGEHQNWSLTQDHEIQ---LTNSKDDCLEAQGLRSK-SVWLFRCHKNGGNQYWYYNHRHRWIQQGQIWVWCLEAQLASGHKVGKVLANKICDKNQLEQQWKVGRNAPYDPQREPH-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . * * . : ::. *. .*:: * * * * . :::: :* *:* : *: ::. * :::**.* . * : :* . : : : *.:.: * . .** **: * : . *::* :. : * : ::* : :*: . *. . : :*: :* .:..:* * : . *:*:*:* ** : .**:*:. : :* :*: : * .: .: : : .*: *. : :: . * : . *: : : ::: : * ..: * : . . *: *:* . . ", "identical_positions": 56, "similar_positions": 115, "identity": "7.98%" }, { "cls_id": "homologset.agr.HGNC:33847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GR74-1", "uniprot_id": "A0A1B0GR74_MOUSE", "id": "A0A1B0GR74-1", "name": "", "aln": "MCSYYHMKKRSVLGCNITIFAVMFSHLSAGNSPCGNQATVLCISRLEFVQYQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJ69-1", "uniprot_id": "IGIP_HUMAN", "id": "A6NJ69-1", "name": "IgA-inducing protein homolog", "aln": "MCSYYHMKKRSVSGCNITIFAVMFSHLSAGKSPCGNQANVLCISRLEFVQYQS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************ *****************:*******.**************", "identical_positions": 50, "similar_positions": 2, "identity": "94.34%" }, { "cls_id": "homologset.agr.HGNC:33848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M07-1", "uniprot_id": "COA5_MOUSE", "id": "Q99M07-1", "name": "Cytochrome c oxidase assembly factor 5", "aln": "MPRYYEDKPEGG-ACAGVKEDLGACLLQSACVLQEGKSPRQCLKE--------GNCRALQYSFFECKRSMLDARSRFRG----RKGY-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LRY3-1", "uniprot_id": "A0ABK0LRY3_RAT", "id": "A0ABK0LRY3-1", "name": "Cytochrome c oxidase assembly factor 5", "aln": "MPRYYEDKPEGG-ACAGVKEDLGACLLQSACVLQEGKSPRQCLKE--------GNCRALQYSFFECKRSMLDARSRFRG----RKGY-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86WW8-1", "uniprot_id": "COA5_HUMAN", "id": "Q86WW8-1", "name": "Cytochrome c oxidase assembly factor 5", "aln": "MPKYYEDKPQGG-ACAGLKEDLGACLLQSDCVVQEGKSPRQCLKE--------GYCNSLKYAFFECKRSVLDNRARFRG----RKGY-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P451-1", "uniprot_id": "COA5_DANRE", "id": "Q0P451-1", "name": "Cytochrome c oxidase assembly factor 5", "aln": "MPKYYEDKEDDGRACSGLREDFKACLLQHDCVVKEGKKPSECLKE--------GHCRSIQVAFFECKRSMLDTRSRFRG----RKGE-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02772-1", "uniprot_id": "COA5_YEAST", "id": "Q02772-1", "name": "Cytochrome c oxidase assembly factor PET191", "aln": "MVAS----------CKDQKKAVAICLQRSPCVMIERHNPQECLDNPELNKDLPELCIAQMKAFLDCKRGIVDMTKRFTGNAPLSTGKYDQQYENLCKGKFDPREEMEKLKLLNSQQKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . :: . ** : **: * :.* :**.: * : :*::***.::* ** * .* ", "identical_positions": 20, "similar_positions": 19, "identity": "16.95%" }, { "cls_id": "homologset.agr.HGNC:33849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9X0-1", "uniprot_id": "D3Z9X0_RAT", "id": "D3Z9X0-1", "name": "", "aln": "--------------------------------------MKPGKQ-------AGR---LREAMSAAPG-------RTAIQPEPSLWLGNQSRWLGLLLLLLPLLG---ITWTEVQ--PPQLPKQVPIVQALSRKESFLILTTHNRLRSQVHPSAANMQRMDWSESLAQLAQARAALCGTSATPNLAATLRNTPDVGWNVQLLPMGSASFVEVVNVWFAEGLQYRHGSAECAHNATCAHYTQLVWATSSQLGCGWQPCFVDQVATEAFVCAYSPGGNWEINGKMIAPYKKGPWCSLCTAS--VSGCFKAWDHAGGLCEVPRNPCRMSCRNLGHLNISTCRCHCPPGYTGRYCQVRCSIQCVHGRFQREECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSPEADTYYGAKMKCQGKGGVLAQIESQKVQDILAFYLDHLETTNKVTDSDFETKNFWIGLTYKAAKDSFRWTTGEHKSFTSFAFGQPDNQ---------GFGNCVEMQASAAFNWNDQRCKTRNRYICQFAQKHYSQWEPGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSQ1-1", "uniprot_id": "CL18A_MOUSE", "id": "Q7TSQ1-1", "name": "C-type lectin domain family 18 member A", "aln": "MTGAEEWKLSMGLEDTVPARLHEHGEASWTAERSHVCSIRQANDSAGALPVAGKPEPMARSLASAPVSPWHHMDRGSTTPAKARSHSASYHCPSSSQICVPGVGSPSAGYGDVPGASGHRPNLLSWPPALSRKESFLILTAHNRLRSRVHPPAANMQRMDWSESLAQLAEARAALCVTSVTPNLASTPGHNSHVGWNVQLMPMGSASFVEVVNLWFAEGLQYRHGDAECAHNATCAHYTQLVWATSSQLGCGRQPCFVDQEAMEAFVCAYSPGGNWDINGKTVAPYKKGTWCSLCTAR--VSGCFKAWDHAGGLCEVPRNPCRMSCRNLGHLNISTCRCHCQPGYTGRYCQVRCSVQCVHGQFRKEECSCICDVGYGGAQCATKVGFPFHTCDLRIDGDCFMVSPEADTYYGAKMKCQGKGGVLAQIESQKVQDILAFYLGRLETTNEVTDSDFETKNFWIGLTYKAAKDSFRWTTGEHQSFTSFAFGQPDNQ---------GFGNCVEMQASAAFNWNDQRCKTRNRYICQFAQKHYSRWEPGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXF7-1", "uniprot_id": "CL18B_HUMAN", "id": "Q6UXF7-1", "name": "C-type lectin domain family 18 member B", "aln": "----------------------------------------------------------------------------MLHPETSPGRG------HLLAVLLALLG---TTWAEVW--PPQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCG-IPTPSLASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQTAIEAFVCAYSPGGNWEVNGKTIIPYKKGAWCSLCTAS--VSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGLVWLSAAMGFGNCVELQASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PBI0-1", "uniprot_id": "M9PBI0_DROME", "id": "M9PBI0-1", "name": "SCP domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MSIKIILFLIA------------------IEVCNQTIGIGLRSLILEAHNRR------------RAKYGNQPMVLDEELCTECSEYADEIVRN--------------------------------------------EGVYTENYLEYLYAT-----------------------------------DPISAKHLQVVCVFREAL--PRECVRIWFHYRGFAEN-----------------------------TKYYRFTAMIWNASTRLG---------VGLG-----------------RIQETRYLVVRYAP-----------PGNILREMASN------------------------------------VPKRPTTFWDAEHIVDHGFEFA---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INR8-1", "uniprot_id": "Q8INR8_DROME", "id": "Q8INR8-1", "name": "SCP domain-containing protein", "aln": "------------------------------------------------------------------------------------------MLLIRSLVIVFLVAIS----------------EFDRNFAINHDNAGIVLREINKR------------RDRHGVPKLTLDNVLSKGCQSYAWKLSKS-----------------------------------------------ATLNYS-----------------------------------------DPTNKDYTESICRFEVKRGALSRCVKNWYNGRKFDILD----------------------------PKAKDFTAMIWRSSVSLG-----------YGDAN--------------INALQGVFVVRYTP-----------PGNVKGLYTDN------------------------------------VPPRKRKQKKKKRENKQKEDCASRQDN---------RYVLLLSILSLVSTNWQS-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. ::. ::* *: * . * : . * :* . * : *.: * : : : . . : : * :* : *.: .: .. :: . ", "identical_positions": 12, "similar_positions": 36, "identity": "2.2%" }, { "cls_id": "homologset.agr.HGNC:3385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDH4-1", "uniprot_id": "D3ZDH4_RAT", "id": "D3ZDH4-1", "name": "Ephrin type-A receptor 1", "aln": "---------------------------------------------------------MERRWPLGLALLLLLLCAPLPPGARAEEVTLMDTSTAQGELG---WLLDPPETGWSEVQQMLN--GTPLYMYQDCPIQEGGDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLFYMESDQDVGIQLRRP---LFQKVTTVAADQSFTIRDLASGSVKLNVEHCSLGHLTRRGLYLAFHNPGSCVALVSVRVFYQRCAETVHGLAHFPHTLPG-PTGLVEVAG-TCLSHAQISLGSSGTPRMHCSPDGEWLVPVGQCQCEPGYEESGGSVGCTACPTGFYRMDMNTLHCLKCPQHSVAESEGSTICTCENGHYRAPGEGPQVACTRPPSAPQNL-SFSASGTQLSLRWEPPRDTGGRQDIRYSVECLQCRGIAQDGGPCQPCGKGVHFSPAASGLTASTVQVEGLEPYANYTFTIKSQNRVSGLDSSSPSSASLSINMGQAESLSGLSLKLVKKEP--------------------------------RQLELTWAGSRLQNPGGNLSYELHVLNQDE-EWHQMVLEPR---VLLTKLQPDTTYIVRVRTLTPLGPGPFSPDHEFRTSPPVSRSLTGGEIVAIIFGLLLG----IALLIGIYVFRSRRG--QRQRQQRQRERTTNVD---------------------------REDKLWLKPYVDLQAYEDPAQGALDFAQELDPAWLIVDTVIGEGEFGEVYRGALRIPS--QDCKTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITEFMENGALDAFLKEREDQLVPGQLVAMLLGIASGMNYLSGHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQLLTDPHSLRTIANFDPRVTLRLPSLSGSDGIPYRSVSEWLESIRMKRYILHFRSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFKD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60750-1", "uniprot_id": "EPHA1_MOUSE", "id": "Q60750-1", "name": "Ephrin type-A receptor 1", "aln": "---------------------------------------------------------MERRWPLGLALLLLLLCAPLPPGARAEEVTLMDTSTAQGELG---WLLDPPETGWSEVQQMLN--GTPLYMYQDCPIQEGGDTDHWLRSNWIYRGEEASRIYVELQFTVRDCKSFPGGAGPLGCKETFNLFYMESDQDVGIQLRRP---LFQKVTTVAADQSFTIRDLASGSVKLNVERCSLGHLTRRGLYLAFHNPGSCVALVSVRVFYQRCAETVHGLAHFPDTLPG-PGGLVEVAG-TCLSHAQISLGSSGTPRMHCSPDGEWLVPVGQCQCEPGYEESSGNVGCTACPTGFYRVDMNTLRCLKCPQHSIAESEGSTICTCENGHYRAPGEGPQVACTRPPSAPQNL-SFSTSGTQLSLRWEPPRDTGGRHDIRYSVECLQCRGIAQDGGPCQPCGKGVHFSPAASGLTTSTVQVQGLEPYANYTFTVKSQNRVSGLDSSSPSSASLSINMGHAESLSGLSLKLVKKEP--------------------------------RQLELTWAGSRPRNPGGNLSYELHVLNQDE-EWHQMVLEPR---VLLTKLQPDTTYIVRVRTLTPLGPGPFSPDHEFRTSPPVSRSLTGGEIVAVIFGLLLG----IALLIGIYVFRSRRG--QRQRQQRQRERTTNVD---------------------------REDKLWLKPYVDLQAYEDPAQGALDFAQELDPAWLIVDTVIGEGEFGEVYRGALRLPS--QDCKTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITEFMENGALDAFLKEREDQLAPGQLVAMLLGIASGMNCLSGHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQLLTDPHSLRTIANFDPRVTLRLPSLSGSDGIPYRSVSEWLESIRMKRYILHFRSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFKD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21709-1", "uniprot_id": "EPHA1_HUMAN", "id": "P21709-1", "name": "Ephrin type-A receptor 1", "aln": "---------------------------------------------------------MERRWPLGLG-LVLLLCAPLPPGARAKEVTLMDTSKAQGELG---WLLDPPKDGWSEQQQILN--GTPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRP---LFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPG-PAGLVEVAG-TCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNL-SFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEP--------------------------------RQLELTWAGSRPRSPGANLTYELHVLNQDE-ERYQMVLEPR---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLG----AALLLGILVFRSRRA--QRQRQQRQRDRATDVD---------------------------REDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPS--QDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFKD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O13146-1", "uniprot_id": "EPHA3_DANRE", "id": "O13146-1", "name": "Ephrin type-A receptor 3", "aln": "-------------------------------------------------------MALFRIYSFLAPFHILVLCQALRN-YPDNEVTLLDSMSAPGDLG---WEAYPSE-GWEEISVMDER-NIPMRTYQVCNVMEAN-QNNWLRTGLIQR-EGAQRVYVEIKFTLRDCNSLPGVPG--TCKETFNVYYHESNNAVAAPLRHIRESQYIKIDTIAADESFTQTDVGDRVMKLNTEVRDISGLSKRGLYLAFQDLGACIALVSVRVFYKRCPLAVLNLARFPDTVTGGDSALVEVRG-TCVEDAEELEG----PRMFCSADGGWLVPIGRCVCRPGFEEVDG--HCQPCRSGFYKASAMDAYCVKCPPHSYSHQDKASECVCERGFYRAESDPRSMACTRPPSAPGNP-ISMVNETAVTLEWSPPRDSGGRGDVSYSVHCRKCSGETGASERCVPCGSGAHFNPRQFGLTHPRVLVTELQPHTNYTFSVEALNGVSDLSPS--PRQLVSVNVTTSQTVS--VILKERKGT--------------------------------DSVTLAWQGPEPVD-GTVVEYEVTYYEKNQQDQNYTVLKTKSNSMTVDGLKPGTTYIFRVRARTDGGYGNYKGEIELETSHEDMLAVGDPNQQTILAISVAGGAVLLVLLVACFIVSGRRCGYIKAKQDPEEEKMQFQHG--------------------------RVKLPETRTYIHPHTYEDPNQAVRDFAKEIEVSNIRIERVIGAGEFGEVCSGRLRLPS--KREIQVAIKSLKAGYSEHQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIVTEYMENGSLDTFLKKHDGQFTVIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVISYGERPYWEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRLIRNPSSLKQLANSAVWEDPVTPEAAVN------TVEDWLDLIKMGQYKEHFSSAGYVTLDSVLYVSSSELDKMGVELAGHQKKILSSIQCLQAHHGTQVQV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHN-VNNWLWSPFIDR-GSANRLYIEIQFTIRDCSLFP--GNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQ----NSDVDINTEVKSIAVN-KKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYET----PTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKN---ESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTG----VLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREI-ENASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILDGQRGQN-IFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: ::::. : : * * : * : : . ** * . . * * : ::** : * * *.*:::*::**:***. :* . *****.: : * : . *.: *. . :.:*.* .:. ::*:*:**:: *:*:::::*:*:* *. . .:*:* .* .* ::* . **: .*. * *. ** * : * * *..*:* * * * :: * ** :* : . :. * * *.** .: :.* **:** * .. * : *..* .. .. .... . * *. .. :.* :. . : : *:* :.**. :.: * ** :. *: .* : . * * . . . : : .*:.: : * .* * .:** * * * :. .* . .: : .*:: :. : ::: :.. :.*:. ::**** *. :*::*:: : :: :** ****:* * *::*. ****:** . :** **:*****.**::: *:**:*: :*:**:**:****:**:**: .:.:: **: ** ***:**. ** ***********:*** :* **::****:* : :: . :* *:*****:********:.* **:******:*:*:***:*:*::** : ***:*:*:::.*****.*:*** *::** :** :*: ** * .: *:.* :* ** . . :.. **: *:* :* ** .*. . : : :::.:* .**: * ****:** . : :. ", "identical_positions": 269, "similar_positions": 272, "identity": "23.91%" }, { "cls_id": "homologset.agr.HGNC:33853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQI0-1", "uniprot_id": "D3ZQI0_RAT", "id": "D3ZQI0-1", "name": "", "aln": "MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKDKQEGIE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08740-1", "uniprot_id": "RPB11_MOUSE", "id": "O08740-1", "name": "DNA-directed RNA polymerase II subunit RPB11", "aln": "MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRGAIKDKQEGIE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1A7-1", "uniprot_id": "RPB1C_HUMAN", "id": "Q9H1A7-1", "name": "DNA-directed RNA polymerase II subunit RPB11-b2", "aln": "MNAPPAFESFLLFEGEK-ITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRTCLLPLRLLP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJE4-1", "uniprot_id": "RPB11_DROME", "id": "Q9VJE4-1", "name": "DNA-directed RNA polymerase II subunit RPB11", "aln": "MNAPPTFESFLLYEGEKKIIKELDTKVTNAAIFTINKEDHTLGNMIRNQLLKDPNVLFAGYKVPHPLEHKFVIRIQTTADYSPQEAFMNAITDLLAELSLFEERFKDAIKEKKEGGD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38902-1", "uniprot_id": "RPB11_YEAST", "id": "P38902-1", "name": "DNA-directed RNA polymerase II subunit RPB11", "aln": "MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAAYKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ** *** ***. : : ***..** ::*::********:*: :**:* :****.*** **: :: :*:*** .*.*::*: ** ..:: :*. :: .*. ", "identical_positions": 50, "similar_positions": 35, "identity": "41.67%" }, { "cls_id": "homologset.agr.HGNC:33854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SPX1-1", "uniprot_id": "CC157_MOUSE", "id": "Q5SPX1-1", "name": "Coiled-coil domain-containing protein 157", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHLLGSQACMDSLRKDLTDLQGTIVDVFSRAGPVRFPSWKFPDRVACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCASYLENLSVEQMMPPARAAGPCMSVGLTVRRFWSNLLRLGLLYQQAVPQKRANQGEISITKPTAKGEPARSPECMTAKFIKPPSPVPGLPLICQGLQSIPVRVSLRSPGGTSEKTKSVYSQTVETALVPCDACTSVQGSLWEVGKVVISLCQSQNLPSSLGQFQKLVKDSLGLKPLPAATVGHWAAEQSKDLTRLNKHVGALTQLVGPLRAQLEDAEGQKDGLRKQVSKLEQALQQEQGQRQRQTE--------EAERTLAKCEHDRHQLLTETCDLKTKVAVLEGDLKQQQKSIQAMEAKAQQLEEEGERRAAAERQVQQLEEQVQ-------LLAGRLDGASQQIRWASTELDKEKARVDSMVRHQESLQAKQRTLLQQLDCLDQEREELRGSLDEAEAQRSELEEQLQSLQSDREQEQCQLQAQQELLQSLQQEKQDLEQVTTDLQLTISELRQQLEELKERERLLVAFPDLHQPEEAQIQ---------------SSSNVTQDMERQVQANAIRIQVLQEENKRLQSMLTKIREVAQQGGLKMVPQGQLWSPPYKGIQGATPPAQAQSAFSGLTGRRQSPGSRTSSTGR---------------------THPGGLRTSPSRQPGGLPSKFSLGDGSHSASCTQNPIRALARLRRKLSPNR-QAGSTYQPQERPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LQI7-1", "uniprot_id": "A0ABK0LQI7_RAT", "id": "A0ABK0LQI7-1", "name": "", "aln": "MHMFMVRSRGDQRPTLTSLTKWKHWKQSQREDSLDTLHPRHRKHTAGGKEVPQRPRGSGGTRPTTGLQAEEHGARYLFGLSDYWRRRGYRLHGSGLHDCDAQGCQSASVWTTGTATRLSSPHEVSNSMARWRRPREKPRRHFRPRPLAVSHFQPRPACTMARYAVAMAASWAPCFRVSRDPWSRRRSGGSSVSLPDTELRLRRRRQGWEGRLRPALNQEARSQKARHLHESRTSQPSPKAGHSRSLQLHGQTSVRGAVGMAHLLGSQACMDSLRKDLTDLQGTIVDVFSRAGPVRFPSWKFPDRVACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCASYVENLSLEQMMPPARVAGPCMSVGLTVRRFWSNLLRLGMHYQQVVPQKRTNQGEISITKPTAKGEPARSPECMTAKFIKPPSPVPGLPLICQGLQSLPVRVSLRSPGGTSEKTKSVYSQTVETALVPCDACTSVQGSLWEVGKVIINLCQSQNLPSSLGQFQRLVQDSLGLKPLPAATVGHWAAEQSKDLTRLNKHVGALTQLVGPLRAQLEEAEGQKDGLRKQVSKLEQTLQQEQGERQRQTE--------EAKRTLAQFEHDRHQLLTETCDLKTKVAILEEDLKQQQKSMQAMEAKAQQLEEEGERRAAAERQVQQLEEQVQ-------LLAGRLDGASQQIRWASTELDKEKARVDSMVRHQESLQAKQRTLLQQLDCLDQEREELRGNLDEAEVQRSELEEQLQSLQSEREQGQCQLQAQQEVLQSLQQEKQDLEQVITDLQLTISELQQQLEELKERERLLVAFPDLHQPVEAQIQ---------------SSSNVTHDMERQVQANDIRIQVLQEENKRLQSMLTKIREVAQQGGLKMVSQGQLWSSPYKGIQGTIPPAQAQSALSGPTGRRQSPGSKTSGSGK---------------------THPGGPRTSPSRQPGSLPSKSSSGDGAHSATCTQNPIRALARLRRKLSPNRGQAGSPYQPQERPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q569K6-1", "uniprot_id": "CC157_HUMAN", "id": "Q569K6-1", "name": "Coiled-coil domain-containing protein 157", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCMSYLENLGSEQMMPPAQAAGPCMSVGLTVRRFWDSLLRLGTLHQQPLPQKGANQRETPTSKPTTKGEPARSPEYLTTKLIKPSSPVLGLPQTCQEPESIPVRASLQFPATTFKNTRSVHSQTIETALVPCDACASVQGSLQKVGKVVISLCQSQNLPSSLGQFQQLVQDSMGLRPLPAATVGRWAAEQRKDLTRLSKHVEAL-------RAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAE--------EDEQCLSEWEHDKQQLLTETSDLKTKMATLERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQLQ---SEREQGQCQLRAQQELLQSLQREKQGLEQATTDLRLTILELERELEELKERERLLVAFPDLHRPTETQIHGGRSSSVESQITCPTDSGNVTDHMERQVQSNDIRIRVLQEENGRLQSMLSKIREVAQQGGLKLIPQDRLWSPSSKGTQGATPPVQAKSTSPGPLGRQHLPSSRTGRTLLGQPCTSPPRQPCTSPPRQPCTSPPRQPCTSPSRQPCSQPSKSLLEGVTHLDTCTQNPIKVLVRLRKRLSPGRGQASSAHQPQERPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTW5-1", "uniprot_id": "F1QTW5_DANRE", "id": "F1QTW5-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHLLGRQDCIDSLRRDLIDLQGALLDVFSKTGPVRFPSWKFPDKLSCNLDLVRLLEEYDYVEDDEEFSQHSHIVLQELLIDRLMLLLQSFNVHAELLLEKQQTLSLDPNETSVSIGPVVKRYWKNLLQLNSQQKQESSCSGNQP------------PSQQSPSVSKTAPNTPTTLKTQSASMSSIHKTSSSSPAFTLQHGSCVSTHSVSCQTVESALVPCEACACVQAVLKENSDAVVSLCQSLGLPCSMQGFLEAVEETQQLGRLSACDISQWASEQRRDMSRVGKHVLEVRETVEPLKRKVKETEMEREKLRKQLSETVNREKEERRKMDEQWERKMQEVKVKSEDAVRRLKQEQEELKRGLTLLEDRNSELTVELKLQTEAKHSLEFERNGLQEEVHRLHSFETMLKEVEESRQ--------------NLEKELRSTQTLLDKERGRNHSVQHQHEALQVKQTALRKHLDVLVQQTEELHSSLEECEDEKADLGNKLKQIMREKDTLQEQLTHQQSQNSSLCTEIESQQTQITELEERVSRLEGMLEEAVQRERLLVAFPELSPQAAPQTT-----------------GDVVCDMEHQLKANLVRIRVLQKENSSLSNSLVRLKEREENQ-----------KASDSGISEMDLRMEAQVMEPQDN------------------------------------SGASSVISSPTSSSSVLHHQTLCLSLHQDVEERYKNIRQAARIR--------SAGTCRRPK----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**** * *::*** ** ****:::****::************:::*:**:* ***.**:* .* **:* ** ** **:****:***** : * * :* . ..:*:* .*:*:*..**:*. :* . . : . :**. .: .*.: . .. :: . :: : .*:** .**:*:*****:**:.**. * : ...::.**** .**.*: * . *::: * *.*. :.:**:** :*::*:.*** : : :::::* ::: **** .: : ::*: .* * : : : . ::::.:* *: : : * :** * :: :::* : : *:** .* : * ::::**. * . ::: :.* ****:.* .*: :::*:**.** :* ::** * *: ***:..*:*.* ::: : ::*: ::: * ** **. .** * :. : *:*. : .*. *** :*********:* .* .:*. .**:*:::* :**:***:** *.. * :::* :: ... .* . :*: . : . :**: .. : . : : *: .*:* .*.: :*: ", "identical_positions": 209, "similar_positions": 225, "identity": "20.31%" }, { "cls_id": "homologset.agr.HGNC:33855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0N4SV92-1", "uniprot_id": "A0A0N4SV92_MOUSE", "id": "A0A0N4SV92-1", "name": "", "aln": "-MAEAGSPVGGSGVARESRRRRKMVWQAWQEQALLSTFKEKRYLSFKERKELAKRMGVSDCRIRVWFQNRRNRSGEEGHASKRSIRGSRRLASPQLQEELGSRPQGRGLRSSGRRPRTRLTSLQRRILGQAFERNPRPGFATREELARDTGLPEDTIHIWFQNRRARRRHRRGRPTAQDQDLLASQGSDGAPTGPEGREREGAQESLLPQEEAGSTGMDTSSPSDLPSFCRESQPFQVAQPRGAGQQEAPTQAGNAGSLEPLLDQLLDEVQVEEPAPAPLNLDGDPGGRVHEGSQKSFWPQEEAGSTGMDTSSPSDSNSFCRESFPSQVAQPCGSGQEDARTQADSTGPLELLLLDQLLDEVQKEEHVPVPLDWGRNPGSREHEGSQDSLLPLEEAANSGMDTSIPSIWPTFCRESQP-PQVAQPSGPGQAQAPTQGGNTDPLELLLYQLLDEVQVEEHAPAPLNWDVDPGGRVHEGSWESFWPQREAGSTGLDTSSPSDSNSFCRESQTSQVAQPCGSGQEDARTQANSTGPLELLLLDQLLDEVQKEEHVPAPLDWGRNPGSREHEGSQDSLLPLEEAANSGMDTSIPSIWPTFCRESQPPQVAQPSGPGKAQAPTQGGNTDPLELFLDQLLTEVQLEEQGPSPVNVEETWEQMDTTPDLPLTPEEYQTLLDML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6RFH8-1", "uniprot_id": "DUX4C_HUMAN", "id": "Q6RFH8-1", "name": "Double homeobox protein 4C", "aln": "MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPE-------------------GRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAP-----------SWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGIS-------------QPAPARG---------------------------DFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDG--------------------------------------------------------------LPGPCAVAQPGPAQAGPQGQGVLAPPTSQG------------------------SPWWGWGRGPQVAGAAWEP-----QAGAAPPPQPAPPDASAASTDASHPGASQPLQ---EPGRSSTVTSSLLYELL------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. ** ***::** . *.:** : *:.: * .: *:.**: :*:.: *:::****.*.*. .: : ..*. * * .. *** ** :*. * :* :***:: **:*:******:*****. *:*********: : **..** .* :: ..* *: * :. .:*: * . .:* : .* *:*. *. *:**. * .:. :**** .: ::*: .:. .. ..: . *..:** .* *. * * :** * * *.* * .**. * . *. . * :* .:**. :**:: .:*.*:.: . ::. . .:** * .*:.: ::. * ** ", "identical_positions": 119, "similar_positions": 128, "identity": "17.6%" }, { "cls_id": "homologset.agr.HGNC:33856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6ND91-1", "uniprot_id": "ASPDH_HUMAN", "id": "A6ND91-1", "name": "Aspartate dehydrogenase domain-containing protein", "aln": "MAD----RGPWRVGVVGYGRLGQSLVSRLLAQGPELGLELVFVWNRDPGRMAGSVPPSLQLQNLAALGERRPDLVVEVAHPKIIHESGAQILRHANLLVGSPSALSDQTTERQLLEASQHWDHAVFVARGALWGAEDIRRLDAAGGLRSLRVTMATHPDGFRLEGPLAAAHSPGP-CTVLYEGPVRGLCPFAPRNSNTMAAAALAAPSLGFDGVIGVLVADTSLTDMHVVDVELSGPRGPTGRSFAVH-TRRENPAEPGAVTG---SATVTAFWQSLLACCQLPSR----PGIHLC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCQ2-1", "uniprot_id": "ASPDH_MOUSE", "id": "Q9DCQ2-1", "name": "Aspartate dehydrogenase domain-containing protein", "aln": "MATSTLPQVPYKVGVVGYGRLGQSLVSRLLAQGSELGLELVFVWNRDPGRMAGSVPPALQLQDLTALEERHPDLVVEVAHPKIIHESGAQILRHANLLVGSPSALADQTTEQQLLEASKRWGHTVFVARGALWGSEDISRLDAAGGLQSLRVTMATHPDGFRLEGPLAAAHSSGP-RTVLYEGPVRGLCPLAPRNSNTMAAAALAAPSLGFDRVIGVLVADLSLTDMHVVDVELLGPPGPSGRSFAVH-THRENPAQPGAVTG---SATVTAFWHSLLGCCQLTSR----PGIHLC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0J9-1", "uniprot_id": "ASPDH_RAT", "id": "Q5I0J9-1", "name": "Aspartate dehydrogenase domain-containing protein", "aln": "MDASMVPRVPHKVGVVGYGRLGQSLVSRLLAQGSELGLELVFVWNRDPGRMAGSVPPALQLEDLTTLEERHPDLVVEVAHPKIIHESGVQILRHANLLVGSPSALADQTTERQLLEASNHWGHTVFVARGALWGCEDISRLDAAGGLQSLRVTMATHPDGFRLEGPLAAAHSSGP-RTVLYEGPVRGLCPLAPRNSNTMAAAALAAPSLGFDRVIGVLVADLSLTDMHVVDVELTGPQGPQAAALPCTPTERTQPSLALSLAPLLLQPSGTAYWAAVSFPPDLGSASAEFPPLPLLSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66I59-1", "uniprot_id": "ASPDH_DANRE", "id": "Q66I59-1", "name": "Aspartate dehydrogenase domain-containing protein", "aln": "MAD-----KALKVGIVGYGHLGQFLVEKIQSEGAEVGLQLAFVWNRNADKLKDSLPKDLILHDLSDFTQRDTDVIVEVCHPLIVKEFGVRFLSHAHFLVGSPSALSDGQLEQDLRTAAKQQGKTLYVPSGALWGGQDIQKMNDSGTLRALSIRMSKHPSCFRLTGGLLSDWTEGEGRRVLYRGSVAELCPLAPNNVNTMAAAAIAASKLGFHGVTGEIVSDTALADYHVVEVDVTGPDG-----FSVK-TMRQNPAKLGAVTG---KATYNSFWSSLLVCKGHGGR------VYLC--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :**:****:*** **.:: ::*.*:**:*.*****:..:: .*:* * *.:*: : :* .*::***.** *::* *.::* **::********:* *::* *::: .::::*. ***** :** ::: :* *::* : *:.**. *** * * : : * ***.*.* ***:**.* *******:**..***. * * :*:* :*:* ***:*:: ** * :. * * :*: ::: ..: .::* :: . : * ", "identical_positions": 113, "similar_positions": 93, "identity": "37.92%" }, { "cls_id": "homologset.agr.HGNC:33857", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CAT8-1", "uniprot_id": "FBX48_MOUSE", "id": "Q8CAT8-1", "name": "F-box only protein 48", "aln": "MKKTSKKNNNFKIPGTELN--SADAERGKEESQRNFVELLPLEVTYKIFSQLDIQSLCRASRTCTGWNCAIRNNDSLWKPHCLTIRAVCQREIDDDIKSGYTWRVILLRNYQKSKVKYEWLSGRYSNIRSPVNLPEKAMCPMDADTWGEILDAELEREVEKLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M155-1", "uniprot_id": "A0ABK0M155_RAT", "id": "A0ABK0M155-1", "name": "F-box only protein", "aln": "MKKTSK-NSNAKVPGMELN--SEDAEGGRKENQSNFVDLLPLEVTFNIFSQLDIPSLCSASRTCTSWNHAIRNNDSLWKPHCLSIRAVCQREVDDDIENGYTWRVILLRNYQKSKVKNEWLSGRYSNIRSPVSLPEKAMCPMDADTWGEILDAELGREVEKLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWF7-1", "uniprot_id": "FBX48_HUMAN", "id": "Q5FWF7-1", "name": "F-box only protein 48", "aln": "MHKNSKRNNNLRVSHTEAN--SVDAEKEKNESQNNFFELLPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSLWKPHCMTVRAVCRREIDDDLESGYSWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GEA9-1", "uniprot_id": "R4GEA9_DANRE", "id": "R4GEA9-1", "name": "", "aln": "---MSVEGAAAPSAGQKLTRWCCSGLQDPLQIERDFSEALPAEMSVRIFGELDVRSLCRASVTCKHWNDIIEGSDHLWRSHCLTGLAVCRREVNGDRLDGCSWKVTLVRNYRKGCVKRRWLKGRYSNIRSADELPANSMCPLDVETWGEILEAELER------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : . . .. : : :* : ** *:: .**.:**: *** ** ** ** *...* **:.**:: ***:**::.* .* :*:* *:***:*. ** .**.****** *. .** : * *:*.:******:*** * ", "identical_positions": 64, "similar_positions": 43, "identity": "39.26%" }, { "cls_id": "homologset.agr.HGNC:33858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BND4-1", "uniprot_id": "F229B_RAT", "id": "B0BND4-1", "name": "Protein FAM229B", "aln": "MPFRFGTQPRRFPVEGGDSSIELESGLSSSASCNGKETSPNRQLRRCPGSHCLTITDVPITVYATMRKPPAQSSKEMRPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF36-1", "uniprot_id": "F229B_MOUSE", "id": "Q8CF36-1", "name": "Protein FAM229B", "aln": "MPFRFGTQPRRFPVEGGDSSIELESGLSSSASCTGKETSPNRQLRRCPGSHCLTITDVPITVYATMRKPPAQSSKEMHPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0N7-1", "uniprot_id": "F229B_HUMAN", "id": "Q4G0N7-1", "name": "Protein FAM229B", "aln": "MPFQFGTQPRRFPVEGGDSSIELEPGLSSSAACNGKEMSPTRQLRRCPGSHCLTITDVPVTVYATTRKPPAQSSKEMHPK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:********************.******:*.*** **.******************:***** ***********:**", "identical_positions": 71, "similar_positions": 7, "identity": "88.75%" }, { "cls_id": "homologset.agr.HGNC:33859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3USH1-1", "uniprot_id": "INSY2_MOUSE", "id": "Q3USH1-1", "name": "Inhibitory synaptic factor 2A", "aln": "MVSKDSGRCILTTPEREVEPAACLALEMRYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLSSGPLGEKREAKAVSCRVAYRKYMTVPARRSIPNVTKSTGVQTSPDLRKCYQTFPLDRKKG-SLKGLPAADAFKSQNNGFLADSKEKSEAGPMEEPRPCSAGRIHKTTALVFHSNEHVNALGQPSGVNCAELCKSPDVLGYPEAVLQNS-RPPSEEPIHQLQGRAKLDRGT-LDSEEPAPLTHGRVFKTEVATVYPPAISTRAPEPGLSNSAAASQWSLCPADEEQRRAAHLNGLQASTGS---AVACSTPVQYLSPECSEQP--------LQNQPSPTAGIGDEEHQQIVPHTEVVDLKAQLQVMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIY-----------------RYVN-----ILFPLCYSE--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4J1-1", "uniprot_id": "D4A4J1_RAT", "id": "D4A4J1-1", "name": "", "aln": "MVSKDTGRCILTTPEQEVEPAACLALEMRYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLSSGPLGEKREAKAVSCRVAYRKYMTVPARRSIPNVTKSTGVQTSPDLRKCYQTFPLDRKKG-SLKGLPAADTFKSQNNGFLADSKEKSEAGPTEDPRPCSAGRIHKTTALVFHSNEHVNALDQPSGVNCAELCKSPDVLGYPEALLQNS-RPPSEEPIHQLQGRAKPDRGT-LDSEEPTPLTHGRVFKTEVATVYPPAKSTRAPEPGLSNSAAASQWSLCPTEEEQRRAAHLNGLQVSTGS---AVACSTPVQCLSPECSEQP--------LQNQPSPTAGVGDEERQQIVPHTEVVDLKAQLQVMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIYSVELDFKQQEDKLQPVLRKLHPVEETQVAPLPYTQEAHSSTPKQKSKTESKKHGRWKLWFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZSG2-1", "uniprot_id": "INSY2_HUMAN", "id": "Q6ZSG2-1", "name": "Inhibitory synaptic factor 2A", "aln": "MVSKDTGKCILTTSESEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLSSGQLGEKREAKPVSCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKG-NLKSLPAADPFKSQNNGFLTDAKEKNEAGPMEEARPCGAGRVHKTTALVFHSNQHMNTVDQPLGVNCTEPCKSPEPLSYGEAALQNSTRPPSEEPDYQLLGRAKQDRGR-PNSEEPAPPALRRVFKTEVATVYAPALSARAPEPGLSDSAAASQWSLCPADDERRRATHLNGLQAPSET---ALACSPPMQCLSPECSEQPSQTHTPPGLGNQPSPTAVAAGEECQRIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIYSVELDFKQQEDKLQPVLRKLHPIEETQVIPSPYSQETYSSTPKQKSKTESKKHGRWKLWFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286Y931-1", "uniprot_id": "A0A286Y931_DANRE", "id": "A0A286Y931-1", "name": "", "aln": "MVSKEAGRCTLSSSESDSE-SGGPSLER----SGADAVRKRNKALQVRFKDICEAQNEVAHRGARD---------RSVSCKVIHRRYMTMPARRSIPNVTKSTGVQTSPDLKKRYQTFPFERKKGNVIKHTALVENHPDQNNGFLSDVKDGKRGARCD-------GHVQQTRVLLHTTPQCSDAKDLCAGPDCSDGKLCPD-LSDAALDQSDANVPGSGAKHKGLPSESEAGVGQQPNCASSTTPTQPLPVRGDCSKISGPIAWTSLTQVECPESPSGS----CARKKD---TAQLNGLQTQSQALPHSASCASQAHIRAHCHSSQ----------NSGPTETQQQGTRG-QLIALPGVDGNVKARLQAMETLISSSQETIKVLLGVIQELERGEAQREGLSYRTGQDTANCDTCRNSACIIYSVELDFKLQEDKLQPLMKRLCPLEEPLYPSLPYAHEVFTSTPKRKSKTESKKHARWKLWFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****::*:* *::.* : * :. :** . ::******************* . . :.***:. :*:***:*********************:* *****::**** :* . .: . .******:* *: .... : *::::* .*:. : : :: . * :*:: .*: *. .:: * * * ..:: . * :. ..:. : .: : :.: * : .: .:*.:.* *. ..: :::*****. : : : :*:. : : *.* . *: * . . * *. ::**:** **.********************:***:************************** : : . *:. ", "identical_positions": 160, "similar_positions": 118, "identity": "33.06%" }, { "cls_id": "homologset.agr.HGNC:3386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBN3-1", "uniprot_id": "D3ZBN3_RAT", "id": "D3ZBN3-1", "name": "Ephrin type-A receptor 2", "aln": "----------------------------------------------------MKLRAAGFCLALLWGCALAAAAAQ----GKEVVLLDFAAMKGELGWLTHPYG-----KGW--DLMQNIMNDMPIYMYSVCNVVSGDQDNWLRTNWVYR-EEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDVDYG--TNFQKRQFTKIDTIAPDEITVSSDFEARNVKLNVEERMVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPEMLQSLARFPETIAVAVSDAQPLATVAGTCVDHAVVPYGGEGPLMHCTVDGEWLVPIGQCLCQEGYEK--VEDACQACSPGFFKSEASESPCLQCPEHTLPSTEGATSCQCEEGYFRAPEDPLSMPCTRPPSAPHYLTAIGMG---AKVELRWTAPQDTGGRKDIVYSVTCEQCWPESGECGSCEASVQYSEPPQALTRTSVTVSDLEPHMNYTFTVEARNGVSDLVNSR-------------------SFRTASVSINQTEP--------------PKVR---LEDRSTTSLSVAWSIPVPQQSRVWKYEVTYRKK--------GDANSYNVHRTDGFSVTLDGLAPGTTYLVQVQALTQEGQ-GAGSKVHEFQTLSTEGSA-----TMAVIGGVAVGVVLLLVLAGIG--FFIHRRRRNLRARQSS------------EDVYFSKSEQLKPLKT------------YVDPHTYEDPNQAVLKFTTEIHPSCVSRQKVIGAGEFGEVYKGTLK-SSSGKKEIPVAIKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMVAGYTAIEKVVQMSNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03145-1", "uniprot_id": "EPHA2_MOUSE", "id": "Q03145-1", "name": "Ephrin type-A receptor 2", "aln": "----------------------------------------------------MELRAVGFCLALLWGCALAAAAAQ----GKEVVLLDFAAMKGELGWLTHPYG-----KGW--DLMQNIMDDMPIYMYSVCNVVSGDQDNWLRTNWVYR-EEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDVDYG--TNFQKRQFTKIDTIAPDEITVSSDFEARNVKLNVEERMVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPEMLQSLARFPETIAVAVSDTQPLATVAGTCVDHAVVPYGGEGPLMHCTVDGEWLVPIGQCLCQEGYEK--VEDACRACSPGFFKSEASESPCLECPEHTLPSTEGATSCQCEEGYFRAPEDPLSMSCTRPPSAPNYLTAIGMG---AKVELRWTAPKDTGGRQDIVYSVTCEQCWPESGECGPCEASVRYSEPPHALTRTSVTVSDLEPHMNYTFAVEARNGVSGLVTSR-------------------SFRTASVSINQTEP--------------PKVR---LEDRSTTSLSVTWSIPVSQQSRVWKYEVTYRKK--------GDANSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQ-GAGSKVHEFQTLSTEGSA-----NMAVIGGVAVGVVLLLVLAGVG--LFIHRRRRNLRARQSS------------EDVRFSKSEQLKPLKT------------YVDPHTYEDPNQAVLKFTTEIHPSCVARQKVIGAGEFGEVYKGTLK-ASSGKKEIPVAIKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMVAGYTAIEKVVQMSNEDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29317-1", "uniprot_id": "EPHA2_HUMAN", "id": "P29317-1", "name": "Ephrin type-A receptor 2", "aln": "----------------------------------------------------MELQAARACFALLWGCALAAAAAAQ---GKEVVLLDFAAAGGELGWLTHPYG-----KGW--DLMQNIMNDMPIYMYSVCNVMSGDQDNWLRTNWVYR-GEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYG--TNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAG--SDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGYEK--VEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMG---AKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSR-------------------SFRTASVSINQTEP--------------PKVR---LEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKK--------GDSNSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQ-GAGSKVHEFQTLSPEGSG-----NLAVIGGVAVGVVLLLVLAGVG--FFIHRRRKNQRARQSP------------EDVYFSKSEQLKPLKT------------YVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F533-1", "uniprot_id": "E7F533_DANRE", "id": "E7F533-1", "name": "receptor protein-tyrosine kinase", "aln": "----------------------------------------------------MDYRRIKRVLFVNVFMNFVFISLQ----KKEEVLLDMVASGAELGWLTSPVK-----DGW--EIGQQAVNGSLLYNYYVCNVEKGEQDNWLRTTFIQRNPAASRVFVELQFNVRDCNTFEAVPLNCKETFNLYTSEADADIG--TAFRKGLFRKVATIAPDEIS-----DRGKMKMNTETKVVDNLSRKGFYLGFQDIGACVAIYSVRVYYKTCPATVQSLAAFPETVAG--GENQALREVAGSCVKNAISE---GQPRIYCTTDGEWVVPMSQCQCESGFEA--LEDTCQECQPGFFKPSVSSEACKPCPKNTEPSGPGATRCSCNDGFYRAPEDPETSACFGLPSAPQSLLSSTAQMSFGRLQLSWKPPADNGGRSDITYSVVCERCEGKT--CQSCGEKVRFEPSNTELKETKVTVSELEPHLNYTFSVEARSGVSQFSHKR-------------------AVSSINTTLHYTDP--------------PKVTAMHLVESSPTSLSLQWSVSHRAKPVATRYELMFRKKENDEEKASGTVTTFTVLVLEKNSAQIKDLSPSTVYLFKVQALSSEGSPGSYSIEQEFSTLPPAG-------NTAVILGAAIGGAVMLFIVVVV--LLLRKRRRNSHTRQGP------------EDTYFSSPDQLKPLKT------------YVDPHTYEDPNTAVLKFASEIHPNHITKQKVIGAGEFGEVYRGILK-APS-RKEVAVAIKTLKPGYTEKQRQDFLSEASIMGQFSHQNIIRLEGVVTKFKHAMIVTEYMENGALDKYLKDHDGEMSSFQLVGMLRGIAAGMKYLSDMSYVHRDLAARNILVNSNLECKVSDFGLSRVLEDDPEGTYTTSGGKIPIRWTAPEAIAYRKFTSASDVWSFGIVMWEVMAFGERPYWDMSNHEVMKAINEAFRLPAPMDCPSAVYQLMLQCWQQDRSKRPRFGDIVSLLDKLLKSPDSLKPIADFDPRVSIRLPSTSGSDGSPFRSVSEWLESIKMSQYSENFSMAGVVSMEQVLQMKSEDIRNIGVRLPGHLKRIAYSILGLKDQTSTLSVFAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDR-GSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFN---QNSDVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTG--REITIIEKQNGTCVDNAEPY---ETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVD--QTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPK------VELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGF-GSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILDGQRGQN-IFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : : *:* .: . * * * ** : : :.. * **:* : :*** : :: * *.*:::*::*.:***. * . . .*****.* * * . ::. : : **..* : .:.:*.* : : :.:**.*:.*:* ***::: :*:*** .** :.:* * ** : : : *:**.:* * * **:* : . * *: *:* :.:* * * ** * ** :: .* *:. *.* .*::* *:* .* *:** * : *..* .. . .. . * . . * * .* :. . :..*.:*:::*** .**. :.* ..** : : :. . :: ... ..* : : .. .: *. . . **: : * . .. . .. : .* .* * .:*:. :.:* *: * .** . * .* *. : .::*.: : ::: :::: ::.. * :... :* *: *********** *: :*: **... :: : :**.****:* :* ** ... ::: *******.* :** * *** **.*****.* *:* *:**::: : **:*******:**.:*: :**::. :**: ******:**.**::*.**********:***::* **::****** :*: .. :*** *****:********::***********:*:*:****::******: **::*:*:*:..:***:*****.*:****::***::*::** *..*** **:* : *:** . . :: . . .:. * :.. *** ***.:* .:* *. ::: ::. ::: :*: * ** *:* :. *. ", "identical_positions": 317, "similar_positions": 307, "identity": "28.15%" }, { "cls_id": "homologset.agr.HGNC:33861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z3B0-1", "uniprot_id": "SIM15_HUMAN", "id": "Q7Z3B0-1", "name": "Small integral membrane protein 15", "aln": "MFDIKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENIAKAKRLKKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UTD9-1", "uniprot_id": "SIM15_MOUSE", "id": "Q3UTD9-1", "name": "Small integral membrane protein 15", "aln": "MLDIKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENIAKAKRLKKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3KNM5-1", "uniprot_id": "SIM15_DANRE", "id": "A3KNM5-1", "name": "Small integral membrane protein 15", "aln": "MIDIKAWAEYVVEWAAKDPYGFLTTVILALTPLFIASALLSWKLAKMIEAKDREQKKKQKRQENIAKAKRAKKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JWM3-1", "uniprot_id": "A0A0G2JWM3_RAT", "id": "A0A0G2JWM3-1", "name": "Small integral membrane protein 15", "aln": "MLDVKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENISKYRCAKNT", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:******************************:***:***********:::************:* : *: ", "identical_positions": 60, "similar_positions": 10, "identity": "81.08%" }, { "cls_id": "homologset.agr.HGNC:33862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABJ8-1", "uniprot_id": "D4ABJ8_RAT", "id": "D4ABJ8-1", "name": "", "aln": "MVQSVATLQSLIPLATWRPGNLSVNFLLMENSEKKLNQKSDDKPRKVRFKISSSYSGRVLKQVFEDGQELESPKEEYPHSFLQEALEPMDGVYGSGEVPKPQLYSPKLTAQRISVFRDSSAYTLAGSQPLFNDYKANDHKPPPIIDFGKIIIYTNNLKIIRTPMDKRDFMRKILQKEEVAEEESLMITGENDGDREQ-------NSSPLPETDRTFLHSQHTQDGLVPEDNCLHCQGSGIATCSLCHGSKFSMLANRFKESYRALRCPACNENGLQPCRICSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TYR5-1", "uniprot_id": "GRCR2_MOUSE", "id": "Q3TYR5-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 2", "aln": "----------------------------MEDSEKKLNQKSDDKPRKVRFKISSSYSGRVLKQVFEDGQELESPKEEYPHSFLQEALEPMDGVYGSGEVPKPQPYSPKLTAQRISVFRDSGAYTLAGSQPLFNDYKANDHKPPPIIDFGKIIIYTNNLKIIRTPMDKRDFMRKILQKEDVAEEASLMITGENDGDREQGCPLPERNGSPLPESERTFLHSQHTQDGLVPED-CLHCQGSGIATCSLCHGSKFSMLANRFKESYRALRCPACNENGLQPCRICSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFK2-1", "uniprot_id": "GRCR2_HUMAN", "id": "A6NFK2-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 2", "aln": "----------------------------MEDPEKKLNQKSDGKPRKVRFKISSSYSGRVLKQVFEDGQELESPKEEYPHSFLQESLETMDGVYGSGEVPRPQMCSPKLTAQRISVFREGNAYTLAGGQPRFNDYKANDHKPLPIIDFGKIIIYTNNLKIIRTPMDKRDFVRKILQKEEEAEEESLMNKEESYGGRDQ-------HDRPLVEAESTLPQNRYTQEGDIPEDSCFHCRGSGSATCSLCHGSKFSMLANRFKESYRALRCPACNENGLQPCQICNQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.*********.******************************************:**.***********:** *************:..******.** *********** ***************************:*******: *** *** . *. *.*:* :. ** *:: *: :.::**:* :*** *:**:*** **************************************:**. ", "identical_positions": 200, "similar_positions": 31, "identity": "70.67%" }, { "cls_id": "homologset.agr.HGNC:33864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEG2-1", "uniprot_id": "A0ABK0LEG2_RAT", "id": "A0ABK0LEG2-1", "name": "Keratin-associated protein", "aln": "MLHSYCHSSGSLGKAPSLSSITHNSNPKSFEDGIFLPSSCHSRTWLLDNFQETHSETSPCQLTNRGQLQCKVDPSVKSPGNSRADQIIRSKSKASERT---KEISPSVPEHASQTCQSRTCKPMGFVAQSYRPASYMTKCCLLRSTVFESSQTLEFESS--PCCSQVPESSSCNSSNNTVSGPHLVESSSTYEPTCCVTGGSQLPSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PX37-1", "uniprot_id": "E9PX37_MOUSE", "id": "E9PX37-1", "name": "Keratin-associated protein", "aln": "MLHSHCQSFRSLGKAPSLSSITHNSNPKSFEDGIVLPSSCHRRTWLLDNFQETYSETSTCQPANCGQNQCKVDPCVQSSQNSRAEQTICSNSKTCERT---REISPAVPESASQTCQSRNYKQVGFVAQSYQPASYMAKCCPLKSTAFESCQTLEFESS--PCCSQVSESRSCNSSSSIVSGLHLVESSNTYEPTCCVTGGSQVPSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3LI81-1", "uniprot_id": "KR271_HUMAN", "id": "Q3LI81-1", "name": "Keratin-associated protein 27-1", "aln": "MPHSHCHSLRSFHNAPPLSAITHGTNPITFEDRLCLPSSFHSRTCFLDNFQETCNETTSCQMTNCEQDLFTDDSCVQSNCFPGVVQTTYSNSRPCERTACQSESSSAGLACVSQPCQSESTQQMGFVAQSCQPASLKGNSCPPKTSKSKNFETLERASSQCQCQSQNPESSSCRPLVNVAPEPQLLESSPGVEPTCCVTGGSQLPSK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **:*:* *: :**.**:***.:** :*** : **** * ** :******* .**:.** :* * . *..*:* . . * *:*:..*** * *.: .**.***.. : :****** :*** :.* ::: :. :*** ** * ** .** **.. . .. :*:*** ***********:***", "identical_positions": 94, "similar_positions": 51, "identity": "45.41%" }, { "cls_id": "homologset.agr.HGNC:33865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1H4-1", "uniprot_id": "A0A8I6A1H4_RAT", "id": "A0A8I6A1H4-1", "name": "", "aln": "MALFRQLSLGSKAALAAATVFVSMILSRSFLAEALELQAWRWLFRLQLALFVNSILLIGSSYIWRSTVSNLSHPPAVESTCFQLWKLVVMTFLALAHSSFFTMLFLVAEEPYLFSLAAYSCLGAYIIMVFFLCILNAMEQAYQFLAWRSGRVVGSPNKTRHLVLRPALAVAVTAVLSTIGLLNAAQPPLVKTVEVPIHQLPPSMNNLKIALLSDIHLGPTVGRTKMEMFVRMVNRLEPDITVIVGDLSDSEASILRTAVAPLGQLRSRLGNYFVTGNHEYYTSDVSNWFTLLESLHVRPLHNENVKISS-----ASGDPDSGGGEREWVCLAGVDDIEADILHYSGHGMDLDKALEGCSPEHATILLAHQPLAAKRALQARPDINLILSGHTHAGQIFPWNVAAYLLNPFFAGLYQVGKATFVYVSPGTAYYGIPMRLGSRAEITELILWRAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z286-1", "uniprot_id": "D3Z286_MOUSE", "id": "D3Z286-1", "name": "", "aln": "MTLFRQLSLGSKAALAAATVFLSMILSRSFLAETLELQAWRWLFRLQLILFVNSIMLIGSSYIWRSTVSNLSHSPAVESTCFQIWKLAVMAFLALAHSSFFTMLFLVAEEPYMFSLTAYSCLGAYIIMVFFLCILNAMEQAYQFLAWRSGRVVGSLDKTRHLVLRPALAVAVTAVLSTIGLLNAAQPPVVKTVEVPIHQLPASMDNLKIVLLSDIHLGPTVGRTKMEMFVRMVNRLEPDITVIVGDLSDSEASVLRTAVAPLGQLHSRLGTYFVTGNHEYYTSDVSNWFTLLESLHVRPLHNENVKIS------APGDPDSAGRDREWVCLAGVDDIEADILHYSGHGMDLDKALEGCSPDDATILLAHQPLAAKRALQARPDINLILSGHTHAGQIFPWNVGAYLLNPFFAGLYQVGKATFVYVSPGTAYYGIPMRLGSRAEITELILWRPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZT21-1", "uniprot_id": "TMPPE_HUMAN", "id": "Q6ZT21-1", "name": "Transmembrane protein with metallophosphoesterase domain", "aln": "MAIFRQLSLGAKATLAAVTVFVSMIASRSYLAESLELRAWRWLLRLQLALFVNSLLLIGSLYIWRSTVSNLCHSPAAESTCFQLWKVVVLAFLALAHSSFFTMFFLVAEEPYLFSLAAYSCLGAYIIMLFFLFILSGMEQAYQLLAWRSGRVVGSLEKTRKLVLRPALAVGVTAVLSVAGILNAAQPPAVKTVEVPIHQLPASMNNLKIVLLSDIHLGPTVGRTKMEMFVRMVNVLEPDITVIVGDLSDSEASVLRTAVAPLGQLHSHLGAYFVTGNHEYYTSDVSNWFALLESLHVQPLHNENVKISATRAQRGGGGSGSGSEDEDWICLAGVDDIEADILHYSGHGMDLDKALEGCSPDHTIILLAHQPLAAKRALQARPDINLILSGHTHAGQIFPLNVAAYLLNPFFAGLYQVAQATFVYVSPGTAYYGIPMRLGSRAEITELILQRSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BG1-1", "uniprot_id": "TMPPE_DANRE", "id": "Q08BG1-1", "name": "Transmembrane protein with metallophosphoesterase domain", "aln": "MFGFGRLSAEGKVGIASGVVFFSMLISRTLISERVDKGTRALLFRVQFLLFINSLLLLGSLYLWKRVVKRLCGARAAPSVPQRCWRIIVLLFLALVHGSYLCMFFLVDTEPHWLSLLSFSCLGVYVILLFFLFVFGCLNRLGKLLSRSRSAEEAVASGS---FRQTVLALIITAVLAVYGLVNAAQPPKVVDVEIPVEKLPESLNGLRLVLLSDIHLGPTVGRSKLQRIVSMVNELNPDVVVIVGDLTDSQVSRLRSAAEPLGQMKPRLGSYFATGNHDYYTADVEGWFELLHSMGIEALHNSHAKVFR------------PERTEDWICLAGIDDLEARMLRYPGHGMDVEKALNGCTTEGPIILLAHQPHAAKQALQQRPDISLVLSGHTHAGQLFPLTILAFLMNPFFCGLYRVSEHTMVYVTPGTGYYGIPMRIASRSEITNIVLKQA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :** .*. :*: .**.**: **: ::* :: : *:*:*: **:**::*:** *:*: .*..*. . *. *. : *:: *: ****.*.*:: *:*** **: :** ::****.*:*::*** ::. ::: ::*: . . . : . :..**: :****:. *::****** * **:*:.:** *::.*::.*************:*:: :* *** *:**:.******:**:.* **:*. ****::.:** **.****:***:**..** **.*: :..***.:.*: .:*:****:**:** :*:*.*****::***:**:.: . ******* ***:*** ****.*:*********:** .: *:*:****.***:*.: *:***:***.*******:.**:***:::* :. ", "identical_positions": 215, "similar_positions": 148, "identity": "47.46%" }, { "cls_id": "homologset.agr.HGNC:33867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K036-1", "uniprot_id": "SDHF1_RAT", "id": "B0K036-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "-----MSRLSRLQRQVLSLYRELLRAGRGKP-----GAEARVRAEFRQHASLPRSDVLRIEYLYRRGRRQLQLLRSGHATAMGTFVRPRGPTEEPVDATAPGNRLDDSDALKNPCEGTGARETRSDGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U276-1", "uniprot_id": "SDHF1_MOUSE", "id": "Q3U276-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "-----MSRPSRLQRQVLSLYRELLRAGRGTP-----GAEARVRAEFRQHASLPRTDVLRIEYLYRRGRRQLQLLRSGHATAMGTFVRPRGPAEEPGDATAPGTRLDDGGAPKNSCEDTGARETRSDGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFY7-1", "uniprot_id": "SDHF1_HUMAN", "id": "A6NFY7-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "-----MSRHSRLQRQVLSLYRDLLRAGRGKP-----GAEARVRAEFRQHAGLPRSDVLRIEYLYRRGRRQLQLLRSGHATAMGAFVRPRAPTGEPG---GVGCQPDDGDSPRNPHDSTGAPETRPDGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B605-1", "uniprot_id": "A0ACD6B605_DANRE", "id": "A0ACD6B605-1", "name": "", "aln": "MIQHIMVRHSKLQKQVLALYRQFLRAAQDKP-----GFIPRIRDEFRTNAAIKKTDVMHIEYLYRRAQRQLELLKDANTKQLGSFSKSK----------------EDS--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3E785-1", "uniprot_id": "SDHF1_YEAST", "id": "Q3E785-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "----MPKRLSGLQKEVLHLYRASIRTAHTKPKENQVNFVNYIHEEFGKYRNLPRKDFTTIEHLLRVGNKKIATFSHPELTNIH---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * **::** *** :*:.: .* . :: ** : :.*. **:* * ..::: : . . : ", "identical_positions": 18, "similar_positions": 24, "identity": "14.06%" }, { "cls_id": "homologset.agr.HGNC:33869", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZMN8-1", "uniprot_id": "CCNI2_HUMAN", "id": "Q6ZMN8-1", "name": "Cyclin-I2", "aln": "----------------------------------------------------------MASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAASLHAASAAVPVRPRRGTAPAG------------KTADAVPAAAPEQAPRPAPQSRKPRNLEGDL----DERRLLCHLQLAQDREARLWRGGKPQD-----------------------------EICDA-FEEVVLW-------------------LLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIG--TPLDFLTIFHALVVLSWPHVL-ELLPQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISD-----------LLKKAQVGDMQYSCCKELVMQQLRSLQSSSCT----------------------------------------DNFVS-------------PAN---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXT9-1", "uniprot_id": "E7EXT9_DANRE", "id": "E7EXT9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLPGEE----ENQRLGTLLLNTLDREMRLWRAPVLKNG-----------------------CIQGSDISPSQYHEVILW-------------------LREMNVIFQFSTETLALGVCVLNSLLATVKTQLKYLKCMAITSLILAAKINEEDEVIASVKDLLEQSRCKFSTAEILRMERVILHKLHWELYLA--TPMDFIHIFHGLLMSGCVD-----QTQKRLCLQAALWSRQLQHCMACHQLWQFKGSILALAIITLELERLTPDWFSVFTG-----------LLRKAQIESTELICCRETVDEYLSSLRFSIPTNAVYILGSGVLVLRGPEGEQRKRQARRAHTAQD------MDDFYDGFCCLYDEQTSACPALI--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95TJ9-1", "uniprot_id": "CYCG_DROME", "id": "Q95TJ9-1", "name": "Cyclin G", "aln": "MSVPVRYSSAAAEYAAEVDCELESTLQQQQQLHLQQQYEQYQHYQYQREQDIAYYCQLQAARQQEQLMQQRTSMSSSVMPGLALPQDHQDHPAALLNGPHNNNIGLAMDAHSINAILVDDEQPSTSAQAAAAAAASAGGSAGAGSGSGLGGAIGGGKLANGINRNAEMPTDWMRIADEGRYGTPGAAGLEYQKYEQQQQLEDLAESEAGAVGGASNNNGESSSSLKKLEDQLHALTSDELYETLKEYDVLQDKFHTVLLLPKESRREVTAGGRDGSAYVLRCLKMWYELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKPIP--AEDLVTISQCGCTAGDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEELENRLEILMCDVKTTVITPSTLALVLICLHLDFHIKESYTRGSPELKHVFEYILFLQQYMRIPDRVFTCGFSIVSGILSHYNGQNKAPYKQRLVWKLSSRTLRVLRPINRFSSDLPTIEEGIPNALDDGLRSRTESISSEEEEDWPTSPIIPIFEQC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: . * : * . :: :: :. *:* * :: : :. ..: .: :.. :* : .: *:: * :::*: ** * : . . .:*: . :. :: ** .* .:* :: . *.:.:: *::.*. . . :: .:*: *. : :. * ***.:* *.*: : : * : :: . * . * * . . : *.: . *: ", "identical_positions": 36, "similar_positions": 90, "identity": "6.34%" }, { "cls_id": "homologset.agr.HGNC:3387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08680-1", "uniprot_id": "EPHA3_RAT", "id": "O08680-1", "name": "Ephrin type-A receptor 3", "aln": "---MDCHLS----------------------------------------------------ILILFGCCVLSCSRELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISG-VDEHYT------PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK--FLEHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVR-GSCVNNSKEEDPPRMYCSTEGEWLVPIGKCTCNAGYEE--RGFICQACRPGFYKALDGVAKCTKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSMACTRPPSAPRN-VISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAINGVSELSSPPRQ--------------------------------FAAVSITTNQAAPSPVMTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS-YTILRARGTNVTISSLKPDTTYVFQIRARTAAGYGTNSRKFEFENSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHSSDEK--------------------------RLHFGNGHLRLPGLRTYVDPHTYEDPTQAVHEFAKELDATNIAIDKVVGAGEFGEVCSGRLKLPS--KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQSKNGPVPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29319-1", "uniprot_id": "EPHA3_MOUSE", "id": "P29319-1", "name": "Ephrin type-A receptor 3", "aln": "---MDCHLS----------------------------------------------------ILVLLGCCVLSCSGELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISG-VDEHYT------PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD-HGVK--FREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVR-GSCVNNSKEEDPPRMYCSTEGEWLVPIGKCTCNAGYEE--RGFICQACRPGFYKASDGAAKCAKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSMACARPPSAPRN-VISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQ--------------------------------YAAVSITTNQAAPSPVMTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYQKQEQETS-YTILRARGTNVTISSLKPDTTYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHSAEEK--------------------------RLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPS--KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISTIKALETQSKNGPVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29320-1", "uniprot_id": "EPHA3_HUMAN", "id": "P29320-1", "name": "Ephrin type-A receptor 3", "aln": "---MDCQLS----------------------------------------------------ILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISG-VDEHYT------PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK--FREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVR-GSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEE--RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRN-VISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQ--------------------------------FAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS-YTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVLIGRFCGY-KSKHGADEK--------------------------RLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPS--KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQSKNGPVPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7P7-1", "uniprot_id": "A0AB13A7P7_DANRE", "id": "A0AB13A7P7-1", "name": "receptor protein-tyrosine kinase", "aln": "---MDCKTL----------------------------------------------------ILFLFFFTLISS-ADFIIHPSNEVNLLDSKASQGELGWISSPSHGWEEISG-VDEHYT------PIRTFQVCNVMEYSQNNWLRTNWIPRNSAQKIYVELKFTLRDCNSIPMVL-TCKETFNLHYLETEEDQGNK--FREHQFSKIDTIAADESFTQMDLGDRILKLNTEVREVGPMTKKGFYLAFQDVGACVALVSVRVYFKKCPFTVRNLAMFPDTVPTDSQSLVEVR-GSCVNNSKEEDPPKMYCSTEGEWLVPIGKCLCNIGYEE--RGVACQACRPGFYKASSGNVKCSKCPPHSYTHQEGSVHCGCEKNYFRADEDPASMACSRPPSAPRN-VISAINETSVILDWNWPADNGGRKDVIFNVVCKRCWPGPRQCEPCRGAVRFLPRAFGLTNTTVTVADLLAHTNYTFEIEAQNGVSFQAPTIRQ--------------------------------YAAVTITTNQAAPSAVTVIRKDRTSRNSISLSWMEPERPNGIILDYEVKYYEKQEQETS-YTILRSKGTNVTLNGLKPDTTYLLQIRARTAAGYGSSSRKFEFETSPDSFSISSENSQVVLIAISSAVAIILLTVVLYIVISRFCRYSKSKHP-DEK--------------------------RLPFGNGHLRLPGIKTYVDPHTYEDPSQAVHEFAKELDASSIAIDKVVGAGEFGEVCSGRLKLPS--KKEICVAIKTLKAGYTEKQRRDFLSEASIMGQFDHPNIIRLEGVVTRSKPVMIVTEYMENGSLDGFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMECPATLYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPSSLKITASTASRPVNLLLDRNSTDITSFHTMGDWLESARTLPCKDAFSGVSYSSCDTLAKTSAEDFKKVGVTIVGPQKKIVSSLTTLETHSKNGPVPV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTR-EATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQNSD---VDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAG--AIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD-GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*: : .* :: .: :::* ***:. :. * * * : .* *:* :* *:: **:* :. **** : :: *.**:::*:*::**:***. :* :*****.* : * : : ..: * ***.*. : : . :.:***::.:. :.***.*:**:* ***:::::*:**: .** ...*:* * :* . . :::* : *:**:*:: :.* *. :*:* : * * *: *** . * * * :*: . **: ***:* : : ** * * ..::* :* *.* **::* * .: :::**.*:.*. * .. . .. . : : :*: * * : * :.:*.:*:::* . *.**.:*.* *.** *: * : :**:.. *.* :: :.:. .*.* :* :.: : ***::: * * :: : *.:: *:. : .* :* * :*:*.:* *:*: *. : :. . *: .:. :: :** *:. :* :* ::: : * :. ::* :* :. : . ::**********.**::***:*:**. *:*: ::*.****:** ****:*. ::* ******* * :** * *** ************:* *:****:*:* **:********** *** :*.:* .:**: *********.*****.**********:*:*::*:**::****** :*: .. **********:***:*** ::*************:************* : *******:::: **** **:** :***********:*.:**.* .*** **:* *:* ** .:. * :** .. . * : . **: . *. .. ..: ::: :::::..:*:*:** ****: *:* ", "identical_positions": 378, "similar_positions": 307, "identity": "33.96%" }, { "cls_id": "homologset.agr.HGNC:33872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB67-1", "uniprot_id": "D4AB67_RAT", "id": "D4AB67-1", "name": "", "aln": "MLGLLGNTTLVCWITGTVLAFLMLLLMLALCLFHRSQEHDVERN-------RIRQARPRLFYGRRLRLPRVVHHHHHRGPHGVTSVGVHQHHH---SPHRLHQHRHHH--HHGHGARR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6B9-1", "uniprot_id": "HRCT1_MOUSE", "id": "Q9D6B9-1", "name": "Histidine-rich carboxyl terminus protein 1", "aln": "MLGLLGNTTLVCWITGTALAFLMLLWLMALCLFHRSQEHDVERN-------RVRQARPRLFHGRRLRLPRLVHHHHHHHVTGVTSVGVHHHHHH--SPHRLHHHKHHHRHHHAHGARR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXD1-1", "uniprot_id": "HRCT1_HUMAN", "id": "Q6UXD1-1", "name": "Histidine-rich carboxyl terminus protein 1", "aln": "MLGLLGSTALVGWITGAAVAVLLLLLLLATCLFHGRQDCDVERNRTAAGGNRVRRAQPWPFR-RRGHLGIFHHHRHPGHVSHVPNVGLHHHHHPRHTPHHLHHHHHPHR-HHPRHAR-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.*:** ****:.:*.*:** ::* **** *: ***** *:*:*:* * ** :* . **:* *..**:*:*** :**:**:*:* * ** : ** ", "identical_positions": 57, "similar_positions": 25, "identity": "48.31%" }, { "cls_id": "homologset.agr.HGNC:33874", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97840-1", "uniprot_id": "LEG9_RAT", "id": "P97840-1", "name": "Galectin-9", "aln": "------------------------------------------------------------------------------------MAFFSTQPPYMNPVIPFTGI-------------------------------------IQGGLQNGLQITLQGTVHPFP----NRIAVNFQTG-FSGNDIAFHFNPRFEEGGYVVCNTKQNGKWGPEERKMQMPFQK--GMPFELCFLVQRSEFKVMVNKNFFVQYSHRVPYHLVDTISVSGCLHLSFINFQNSTAAPVQPVFSTMQFSQPVQFPRMPKGRKQRTQGFQPALQAPVAQTIIHTVHSIPGQML-STPGIPPMAYPTPAYTIPFFT--SIPNGFYPSKSINISGVVLPDAKRFHINLRCG------GDIAFHLNPRFNEK--------VVVRNTQINNSWGPEERSLPGRMPFNRGQSFSVWILCEGHCFKVAVDGQHICEYYHRLKNLPDINTLEVAGDIQLTHVQT--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08573-1", "uniprot_id": "LEG9_MOUSE", "id": "O08573-1", "name": "Galectin-9", "aln": "------------------------------------------------------------------------------------MALFSAQSPYINPIIPFTGP-------------------------------------IQGGLQEGLQVTLQGTTKSFA----QRFVVNFQNS-FNGNDIAFHFNPRFEEGGYVVCNTKQNGQWGPEERKMQMPFQK--GMPFELCFLVQRSEFKVMVNKKFFVQYQHRVPYHLVDTIAVSGCLKLSFITFQNS-AAPVQHVFSTLQFSQPVQFPRTPKGRKQKTQNFRPAHQAPMAQTTIHMVHSTPGQMF-STPGIPPVVYPTPAYTIPFYT--PIPNGLYPSKSIMISGNVLPDATRFHINLRCG------GDIAFHLNPRFNEN--------AVVRNTQINNSWGQEERSLLGRMPFSRGQSFSVWIICEGHCFKVAVNGQHMCEYYHRLKNLQDINTLEVAGDIQLTHVQT--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47967-1", "uniprot_id": "LEG5_RAT", "id": "P47967-1", "name": "Galectin-5", "aln": "------------------------------------------------------------------------------------MSSFSTQTPYPN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAVPFFT--SIPNGLYPSKSIVISGVVLSDAKRFQINLRCG------GDIAFHLNPRFDEN--------AVVRNTQINNSWGPEERSLPGSMPFSRGQRFSVWILCEGHCFKVAVDGQHICEYSHRLMNLPDINTLEVAGDIQLTHVET--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DKI2-1", "uniprot_id": "LEG9C_HUMAN", "id": "Q6DKI2-1", "name": "Galectin-9C", "aln": "------------------------------------------------------------------------------------MAFSGCQAPYLSPAVPFSGT-------------------------------------IQGGLQDGFQITVNGAVLSCSG---TRFAVDFQTG-FSGNDIAFHFNPRFEDGGYVVCNTRQKGTWGPEERKMHMPFQK--GMPFDLCFLVQSSDFKVMVNGSLFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRAVPVQPAFSTVPFSQPVCFPPRPRGRRQKPPSVRPANPAPITQTVIHTVQSASGQMFSQTPAIPPMMYPHPAYPMPFIT--TIPGGLYPSKSIILSGTVLPSAQRFHINLCSG------SHIAFHMNPRFDEN--------AVVRNTQINNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHVFEYYHRLRNLPTINKLEVGGDIQLTHVQT--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1MZN0-1", "uniprot_id": "A0A8M1MZN0_DANRE", "id": "A0A8M1MZN0-1", "name": "Galectin", "aln": "------------------------------------------------------------------------------------MAFYQQQ-PFYNPRIPFRGP-------------------------------------IQGGLQDGKSIIISGRVLPGA----NRFHVNLQCGSHSGANVALHFNPRYEDTDYVVHNSYLNRTWGSEERKYESPFAK--GQTFTLQILVAQDRYKISTNGRHFMDYKHRIPFTQVDTVAVEGMVEVNSVAFQNP----------------APYFPPQP-----AFPGFIPPQAGYAPQYAVPPGCG------------FPAFPSAPNYTIPYKT--VMNGGLHPGKNIVINGIVNPNAKRITFNLCYR------SGIAFHYNPRFDEN--------VVVRNTNQMEKWGAEER--FGGLPFHKGQPFQVTISCNPQHYNVFVNGKQVHTYKHRYTKLNDIDILEICGDLQLTSVQA--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPI6-1", "uniprot_id": "Q9VPI6_DROME", "id": "Q9VPI6-1", "name": "Galectin", "aln": "MTAIILLACHSVRELVDLSDALWQNTFNIERSLNYYRIKRRLELFRFHCRELWLRQVSKTSDPMHRKAGIDFAAIEAGADCVLNMDAFDDTTTELHKRFLQAEGTRPFPSDCISGIEVVDGNEFKASFYEYADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNNDS-----RDVALHINPRLPQN-YIVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVKGDVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNTQSDSSP---------KRNNSSNDLGLTLPYYG-ALPPNSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTN-FRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYKVS-PEVVDTVYIQGDVKLWNVTLEKNQMIKGKNMRVYQN----PWFFSE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPI7-1", "uniprot_id": "Q9VPI7_DROME", "id": "Q9VPI7-1", "name": "Galectin", "aln": "------------------------------------------------------------------------------------MSVYPGACTVALRRVMDAMS---------------------LFYEKRSEAHRRKHFKVIQCPRPGLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQN-YITRNSRLKGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYVSEYPIRLTHS--------LPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKF---------LYQPS-----LPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDWVNCTVSRLNTS-LRPGGAFVIVIACRDSYYELFVNNRSLFHFKYQMR-PECVDIVNIRGDIKLWEVAIQGNTTYKKPKVRSAMERAISAWKRAEIPQLQI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:*: . : . : :.* * . : : : ::*: .* * . : *.: * : * * : * * :: *: : : : :: :: : : **::* * ", "identical_positions": 18, "similar_positions": 38, "identity": "3.39%" }, { "cls_id": "homologset.agr.HGNC:33876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1M3-1", "uniprot_id": "TSPY1_RAT", "id": "Q9R1M3-1", "name": "Testis-specific Y-encoded protein 1", "aln": "MENSEEESVGVAPQEFRELVLLESSLLEGEPSVQAPEQSPGAPAGDNQMVKPLVICGPVEDWVPLAEVLHHPDTCEEGDEATMAELKVTEVVDVKNEGEEVKDQKQEGEQDQQPELEKNPEQACDSKDQQGIQRLPLSGGGPAERRSKMEELELLQLELSFVNARCSGAFARIKAKVAKMRRPHFDRRKTIIQGIPGFWAKAMMNHPQMSSIISNQDEDLLSYMLSLEVEEYNPGLRMCR-----MMFFFS-ENPYFRNDIVTKDYQLS------IIGYKESDSSTIEWIG-----------QAEHGYANCMQDTTRLTFFNWL------CAHKFPGSNRIAEIIMDDLWPNPLYYY--------PKEDHS----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CV98-1", "uniprot_id": "TSPY3_HUMAN", "id": "P0CV98-1", "name": "Testis-specific Y-encoded protein 3", "aln": "------------------------MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEE--EGLVERREEAQR---------AQQAVP-----GPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCK-----IMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYP-----------DYEVEAYRRRHHNSSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKR----MKPPEEGTETSGDSQLLS------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53997-1", "uniprot_id": "SET_DROME", "id": "P53997-1", "name": "Protein SET", "aln": "-----------------------------MSSVPKRAKLDGAPADGN----------------------TSAAAGNNEEESE-----------------------------------------------------------------ALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYR-----INFHFD-ENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLL---KLLLTKPYGNKKKRNSEYKTFFDWF------SDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEVEPEDEEDNEDNDEEAFDDEDGEDGEGEEEEEDEDDK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53853-1", "uniprot_id": "VPS75_YEAST", "id": "P53853-1", "name": "Vacuolar protein sorting-associated protein 75", "aln": "---------------------------------------------------------------------MMSDQENENEHAK-----------------------------------------------------------------AFLGLAKCEEEVDAIER-------EVELYRLNKMKPVYEKRDAYIDEIAEFWKIVLSQHVSFANYIRASDFKYIDTIDKIKVEWLALESEMYDTRDFSITFHFHGIEGDFKEQQVTKVFQIKKGKDDQEDGILTSEPVPIEWPQSYDSINPDLIKDKRSPEGKKKYRQGMKTIFGWFRWTGLKPGKEFPHGDSLASLFSEEIYPFCVKYYAEAQRDLEDEEGESGLSADGDSEDDDGSLGEVDLPLSDEEPSSKKRKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: : : : *:. :: . . . :* ::* :. :. ** : :* ..: : .: . : : .::** : :.* : *.:. :** : :. * . .*:* . . .:*.*: : . .: :*.:: .::: : ** : ", "identical_positions": 20, "similar_positions": 69, "identity": "4.94%" }, { "cls_id": "homologset.agr.HGNC:33877", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWL6-1", "uniprot_id": "A0A8I5ZWL6_RAT", "id": "A0A8I5ZWL6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRGAWMCRQYDDGLKIWLAAPRENEKPFID--------SERAQKWRLSLASLLFFTVLLSDHLWFCAEAKLTRTRDKEHHQQQQQQQQQQQQQQQQQQQQQQRQQQRQRQQQRQRQQEPSWPALLASMGESSPAAQA----------------------------HRLLSASSSPTLPPSPG--GGGGS----------------------------------------------------------------------------------KGNRGKNNRSRALFLGNSAKPVWRLETCYPQGASSGQCFTVESADAVCARNWSRGAAAGEEQSSRGSRPTPLWN-----------------------------------LSDFYLSFCNSYTLWELFSGLSSPSTLNCSLDVVLTEGGEMTT---------CRQCIEAYQDYDHHAQEKYEEFESVLHKYLQSDEYSVKSCPEDCKIVYKAWLCS---QYFEVTQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNCRKTIPCKQYCLEVQTRCPFILPDNDE----VIYGGLSSFICTGLYETFLTNDEPECCDIRSEEQSTPRPKGTVDRRD-SCPRTSLTVSSATRLCPGRLKLCVLVLILLHTVLTASAAQNSTGLGLGGLPTLEDNSTRED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CCS2-1", "uniprot_id": "NALF1_MOUSE", "id": "Q8CCS2-1", "name": "NALCN channel auxiliary factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRGAWMCRQYDDGLKIWLAAPRENEKPFID--------SERAQKWRLSLASLLFFTVLLSDHLWFCAEAKLTRTRDKEHHQQQQQQQQQQQQQQQQQQQQQQRQQQRQRQQQRQRQQEPSWPALLASMGESSPAAQA----------------------------HRLLSASSSPTLPPSPG--GGGGS----------------------------------------------------------------------------------KGNRGKNNRSRALFLGNSAKPVWRLETCYPQGASSGQCFTVESADAVCARNWSRGAAAGEEQSSRGSRPTPLWN-----------------------------------LSDFYLSFCNSYTLWELFSGLSSPSTLNCSLDVVLTEGGEMTT---------CRQCIEAYQDYDHHAQEKYEEFESVLHKYLQSDEYSVKSCPEDCKIVYKAWLCS---QYFEVTQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNCRKTIPCKQYCLEVQTRCPFILPDNDE----VIYGGLSSFICTGLYETFLTNDEPECCDIRSEEQTAPRPKGTVDRRD-SCPRTSLTVSSATRLCPGRLKLCVLVLILLHTVLTASAAQNSTGLGLGGLPTLEDNSTRED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1AL88-1", "uniprot_id": "NALF1_HUMAN", "id": "B1AL88-1", "name": "NALCN channel auxiliary factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRGAWMCRQYDDGLKIWLAAPRENEKPFID--------SERAQKWRLSLASLLFFTVLLSDHLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQR-----------RQQEPSWPALLASMGESSPAAQA----------------------------HRLLSASSSPTLPPSPGDGGGGGG----------------------------------------------------------------------------------KGNRGKDDRGKALFLGNSAKPVWRLETCYPQGASSGQCFTVENADAVCARNWSRGAAGGDGQEVRSKHPTPLWN-----------------------------------LSDFYLSFCNSYTLWELFSGLSSPNTLNCSLDVVLKEGGEMTT---------CRQCVEAYQDYDHHAQEKYEEFESVLHKYLQSEEYSVKSCPEDCKIVYKAWLCS---QYFEVTQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNCRKTIPCKQYCLEVQTRCPFILPDNDE----VIYGGLSSFICTGLYETFLTNDEPECCDVRREEKSNNPSKGTVEKSG-SCHRTSLTVSSATRLCNSRLKLCVLVLILLHTVLTASAAQNTAGLSFGGINTLEENSTNEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5P3-1", "uniprot_id": "A0ACD6B5P3_DANRE", "id": "A0ACD6B5P3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSGARKCRQRDNGLKNWCAP-RENEKPFTD--------SERAQRWRLSLASLLFLTVLLSDHLWFCAEAKMTRTRDK-----------------------------------------------LASED---------------------------------------MSANHRPDLPPTHS------------------------------------------------------------------------------------------SLRRNED---AIFVVNSTKPLWQLETCHTDSLSEN-CFTFVDADHLCR-----GLSETEG--------TRWVN-----------------------------------MSDLYLSFCNSYSLMDLLYGSLSPDNLNCSLDAVMD--GDQNR---------CSLCVQAYQRYDLHAQEKYEEFEMMTDKY-ETDVYSVRTCMEECKTVYKPWLCA---QYFQSPR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SACSHKIPCEQYCLEVQQRCPFILPDNDD----LIHGGTPSFICTGLSKRPDTNQEPECCDVRWDQMSNNLSRGTLKRTQPSCQHTSVTSSGAPRLGHSRLKLCLLVLVLLHTVATMTANQNSTCLTT--IFPLDDNAPREE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7V0-1", "uniprot_id": "Q9I7V0_DROME", "id": "Q9I7V0-1", "name": "", "aln": "MRPGPGLVVMALAFISGARRGSSSSISSATATPTAAATSAAAAAAAAATSAASTSAAAAAAANTAGGRKRGRSGGGVGGGGVATTLPSTGESSSSSFVRSSGSYLLPIFLPHYLDFALQFHPQLPPREYSQGRAHSESWASSRIADRLQQRRRRRESSSSRDIAGRAGGTGGSGADSGGLAATTGHSTESSEANNQEDGEDRGLTVQFPSSQAYDEDQDIFALVAEDDLLSEESFDRLIKLNEDADEEDYNLQQQHLPQHKQQQQQPGAETEIDTEPESETETETETETDTEAEVEVERETEQQQQDESRLIDEGVLQHSDHSNSHSKEFAISYDNNNNKREASGHILDAQTAQLIGHKDNTVPAVASTESAGGGSITTSLPAPVDLKKSILGTATSLTRLNPWISACDLAQPGTGTDLQGQCSAGTLPMAWVDEGPGPPTCPRSCAEQQQQKPVASKAKRSATSNNKVKYFVNYKTTQMRLRRAGDHAMDATDSHSPLASERPPSTTDDQDVDVSSTTEEAEPEPTLSYSHLHAQEPVLAHQQDPREREQEQQEQQQCLEYLGDSAESSPQHLCGLQSPGHLLERLKVLRLRNCCERSVFSSLHTLALNASLTDRQECVRVLSDLLDVDGLANRITCELAEILFRFDCRQVYSLINQCDDCKEAYRRWVCSTLVPYFAEPKDVSPQPKDEGQGKGKRSARSAASAEATAMADGIKHKSLKLISNNNKSNNGNNMNERQINQKHDKSSNANANANSNASKDIDRSAEEAIDRDLVQTFYDVVGLSKPRHGEEEVLPENEAGLGRSADSEVDKGAEPDRKRSRNREAELELDTEAEAEQQSNNFISTANNSDPRATDPVISKLQKRSTRKTEFRKRRRIRPCLSVCQTVEQKCPYLLPADRAPALPTQYAGEPTFLCLDQN-IPETGAQLEKSSYGPNDCCYSYCNGPASGICTVCQDFGQPGTEEREMAGNSTRRVHNITLSLSSHPGEHARAKSVALALRNVSQTGSDPDAVETLLDRLPYYASHDGIFYYDEEGEMPHASLSGDCAVVPAATTRCTIPYYASGTGAVAKPPTQLLVWLSALLGLLSSCGAARQRWSCQWSSGCGGHRARSRQAVACEANCHEQELVKSRSCSQRSPKVRREKPGQDQDAELVAFRTWLWSSSWHAYKLTCSKIRYFSSRSRFKGETRAARSANSKDPSGLQWSRAAGCTRTRNYRFFYYYNYNINDWWRRWWRCLSSGAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..: ::* . : ..:.: : :* . *: *: :. .:. : : ::.: ::: * . . : . :*. . . * . . :. * .. :*. . .. . ..: :: . . * . .. :*. : .*: **. *: * :. * *:. *: : :: : **: . ::** .*: *:*: ** .: : ** . * *: :**::** : :.* .:*:* . *. : * .. :: .*. . * . . : .: . : : : * : * ::. * : .:. : ", "identical_positions": 46, "similar_positions": 129, "identity": "3.7%" }, { "cls_id": "homologset.agr.HGNC:33879", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWJ1-1", "uniprot_id": "D3ZWJ1_RAT", "id": "D3ZWJ1-1", "name": "", "aln": "MQPNKMTSELSLLVGCASGVTPGGDRMQRAGGGWKLKRAASGRCAHFQNGGYSFSCTGRCKKRWPRIVVVTVPWNGMLRTALSRMPTLLRSVRTRDSGPRQLWDLGARLKTAKRL-RGWAWG----WRSSSSAPGSEHAAALGRVKADHYQLVYTCKVCGTRSSKHISKLAYHQGVVIVTCPGCQNHHIIADNLSWFSDLKGKRNIEEILAARGEEVRRVCGDGALELILEVAEPP---ATPEGGED--PTHPGKMDQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D113-1", "uniprot_id": "DNLZ_MOUSE", "id": "Q9D113-1", "name": "DNL-type zinc finger protein", "aln": "----------------------------------------------------------------------------MLRTALSRMPTLLRSVRTRDSGPRRLWDLGARLKTAERL-RGWAWGWASGWRSSSSAPGSGRAAALGRVEADHYQLVYTCKVCGTRSSKRISKLAYHQGVVIVTCPGCQNHHIIADNLSWFSDLKGKRNIEEILAARGEEVRRVSGDGALELILEAAVPP---DTPEGDED--PPNPGKMGQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SXM8-1", "uniprot_id": "DNLZ_HUMAN", "id": "Q5SXM8-1", "name": "DNL-type zinc finger protein", "aln": "----------------------------------------------------------------------------MLRTALRGAPRLLSRVQPRAPCLRRLWGRGARPEVAGRR-RAWAWG----WRRSSSEQGPGPAAALGRVEAAHYQLVYTCKVCGTRSSKRISKLAYHQGVVIVTCPGCQNHHIIADNLGWFSDLNGKRNIEEILTARGEQVHRVAGEGALELVLEAAGAPTSTAAPEAGEDEGPPSPGKTEPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1P7-1", "uniprot_id": "DNLZ_DANRE", "id": "A1L1P7-1", "name": "DNL-type zinc finger protein", "aln": "---------------------------------------------------------------MNSRLCYLLFRPRLLRSRGAGVLSVPETQRVTLARVRHEESNSAFTNSTLRSDVGHDTG------LGLSFCRSFSTEAIGQLQSTHYHLVYTCKVCSTRSMKKISKLAYHKGVVIVTCPGCKNHHVIADNLKWFSDLEGKRNIEEILAAKGESVRRVEGSEALEIVNEESRNN-----PDEQKP--AHLSDGSDKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXR1-1", "uniprot_id": "Q9VXR1_DROME", "id": "Q9VXR1-1", "name": "DNL-type domain-containing protein", "aln": "----------------------------------------------------------MSALKKFYKISAGVRRGALLTSSRRTQIDALNSPQLQLQVHHFATKTQTAVFSSSNNYTCICRSIHCSKPVDDADKTVATNSIPLAKLEAKMQLIYTCKVCQTRNMKTISKLAYQRGVVIVTCEGCSNHHLIADNLNWFTDLDGKRNIEEILAEKGEKVVRLT-DGNCEFLPKHD--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42844-1", "uniprot_id": "ZIM17_YEAST", "id": "P42844-1", "name": "Mitochondrial protein import protein ZIM17", "aln": "-------------------------------------------------------------------MIPRTRTLLQSKIPITRYFARCWAPRVRYNVCRTLPAAALHTNIIAHN--------------EVKKDDKKVHLGSFKVDKPKMMIAFTCKKCNTRSSHTMSKQAYEKGTVLISCPHCKVRHLIADHLKIFHDHH--VTVEQLMKANGEQVSQDVGDLEFEDIPDSLKDVLGKYAKNNSEN-ASQLPHPSQK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : :*** * **. : :** **.:*.*:::* *. :*:***:* * * . .:*::: .**.* : . * : . ", "identical_positions": 26, "similar_positions": 31, "identity": "10.04%" }, { "cls_id": "homologset.agr.HGNC:3388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZK3-1", "uniprot_id": "D3ZZK3_RAT", "id": "D3ZZK3-1", "name": "receptor protein-tyrosine kinase", "aln": "--MAGIFY-----------------FILFSFLFGICDAVTGS-----------------------------------RVYPANEVTLLDSRSVQGELGWIASPL-----EGGWEEVSIMD-EKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKER--FIRESQFGKIDTIAADES-FTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEE--QNGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNL-ISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQS--------------------------------VSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYR-IVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLL-VSVSGSVVLVVILIAAFVISRRRSKYSQAKQEAD----------------------EEKHLNQG------VRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPG--KREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR---------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGPESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03137-1", "uniprot_id": "EPHA4_MOUSE", "id": "Q03137-1", "name": "Ephrin type-A receptor 4", "aln": "--MAGIFY-----------------FILFSFLFGICDAVTGS-----------------------------------RVYPANEVTLLDSRSVQGELGWIASPL-----EGGWEEVSIMD-EKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKER--FIRESQFGKIDTIAADES-FTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEE--QNGECQACKIGYYKALSTDASCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNL-ISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQS--------------------------------VSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYR-IVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLL-VSVSGSVVLVVILIAAFVISRRRSKYSKAKQEAD----------------------EEKHLNQG------VRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPG--KREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR---------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54764-1", "uniprot_id": "EPHA4_HUMAN", "id": "P54764-1", "name": "Ephrin type-A receptor 4", "aln": "--MAGIFY-----------------FALFSCLFGICDAVTGS-----------------------------------RVYPANEVTLLDSRSVQGELGWIASPL-----EGGWEEVSIMD-EKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKER--FIRENQFVKIDTIAADES-FTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEE--RSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNL-ISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQS--------------------------------VSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYR-IVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLL-VSVSGSVVLVVILIAAFVISRRRSKYSKAKQEAD----------------------EEKHLNQG------VRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPG--KREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR---------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O13148-1", "uniprot_id": "EPA4A_DANRE", "id": "O13148-1", "name": "Ephrin type-A receptor 4a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IGIGEFGEVCSGRLKMPG--KREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKLIRNPNSLKRTGGEIARPNTTLLEPSSPE-----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDT-TREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQNSD----VDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSP-EVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHS-DIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTR---------GGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILDGQRGQ-NIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ****:** ****:* ::* *******.* ::* * ***:************:* *:****:.:***************:*** ***:* .:**: :****.***.*****.**********:***::*:**::***:** :*: .. ***** *****:********::*************:*:************: *******:**:*****.***** :*:*********:*:.**.*..**. **:* *:*:** * . .. :*: . : ", "identical_positions": 191, "similar_positions": 61, "identity": "16.98%" }, { "cls_id": "homologset.agr.HGNC:33882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2Z2-1", "uniprot_id": "A0A0G2K2Z2_RAT", "id": "A0A0G2K2Z2-1", "name": "Inositol polyphosphate 5-phosphatase K", "aln": "-----------------------MTTASLRKPSA---------------------------------------------PKELMLSIHVVTWNVASAAPT-VDLSDLLQLN----------NEDLNLDIYIIGLQEMNYGIISLLSDAAFEDPWSSFFMDMLSPLNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGYWGNKGGINICLKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFG-LLFVQECITK-KRYKELWEKDQLFIAKKQ-DQLLREFQEGPLLFPPTYKFDRHSNNYDT---------SEKKRKPAWTDRILWRLKRQPAKANPSG-----------------FLLTQKDYVSHMTYSISDHKPVTGTFDLELNPLMSVPLITMMPEYLWTKENDMLINYTSTPEFLSSPWDWIGLYKVGMRHINDYVSYVWVGDN-------------------------------------QVSRGNNPNQVYINISAIPDTEEQFLLCYYSNN----LHSIVGISQPFKIP------SGFFLREDTLSELEPQL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5L6-1", "uniprot_id": "INP5K_MOUSE", "id": "Q8C5L6-1", "name": "Inositol polyphosphate 5-phosphatase K", "aln": "--------MQHGDRNTPGYREGIMSAVSLRRPSA---------------------------------------------PKGFALSVHVVTWNVASAAPT-VDLSDLLQLN----------NQDLNLDIYIIGLQEMNFGIISLLSDAAFEDPWSSLFMDMLSPLNFVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSTPTGLYGYWGNKGGVNVCLKLYGYYVSIINCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFG-LLFVQESITR-KYYKELWEKDQLFIAKKN-DQLLREFQEGPLLFPPTYKFDRHSNNYDT---------SEKKRKPAWTDRILWRLKRQPSQASPLASSVPTSY----------FLLTLKNYVSHMAYSISDHKPVTGTFDLELNPLMSVPLITMMPEHLWTMENDMLISYTSTPEFLSSSWDWIGLYKVGMRHINDYVAYVWVGDN-------------------------------------QVSYGNNPNQVYINISAIPDTEDQFLLCYYSNN----LHSVVGISQPFKIP------IRSFLREDTLYEPEPQI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT40-1", "uniprot_id": "INP5K_HUMAN", "id": "Q9BT40-1", "name": "Inositol polyphosphate 5-phosphatase K", "aln": "--------------------------MSSRKLSG---------------------------------------------PKGRRLSIHVVTWNVASAAPP-LDLSDLLQLN----------NRNLNLDIYVIGLQELNSGIISLLSDAAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDFG-LHFVRESIKN-RCYGGLWEKDQLSIAKKH-DPLLREFQEGRLLFPPTYKFDRNSNDYDT---------SEKKRKPAWTDRILWRLKRQP-CAGPDTPIPPASH----------FSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDS-------------------------------------KVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNS----LRSVVGISRPFQIP------PGS-LREDPLGEAQPQI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AHJ9-1", "uniprot_id": "A0A8M3AHJ9_DANRE", "id": "A0A8M3AHJ9-1", "name": "", "aln": "MSSSMEEISEYFSEKLQRQRSDSAASSSTQSTSSRQHVRQRLAMLLTCVDDLDTDHKLQTQVAKTLDEAFLVCRQIAGRPKKNPFRLYVVTWNVATAEPP-DDVNALLQLN----------SPKK-PDLYVIGLQEVRAAPLKFVSDLAFEDSWSHLFMDTLSPLHYIKVSSIRMQGLLLLFFSKLEHVPFIRDIQVTYTRTGLYGYWGNKGGVTIRLSFYGHMLCFLNCHLTAHMNYASQRVDEFEHILDAQNFNTKNTPHVLDHKVVFWFGDLNFRIEDHG-MLFVRNCITS-QRFNLLWPKDQLTMMKQK-EVILQKFEEGPLDFQPTYKFDLNSDNYDTRVQTTWFGFNGKKRKPAWCDRILWRVKPKASLTENTNEEEPEKQQEEEREDEFPLKMTQEYYTSKMEYGISDHKPVIGIFRLELRKMYETPLVQVFAEGEWSADFDAVITYRLLQAFASSAWDWIGLYKVGFKSVSDYITYAWVKDD-------------------------------------QVSFNEELFQVYMNKDEIPVLGGECVLCYYSSN----LQCIVGISQPFKVQE-----SRAAIEEGLVPENINGLNQALAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHS8-1", "uniprot_id": "M9PHS8_DROME", "id": "M9PHS8-1", "name": "Inositol polyphosphate-related phosphatase domain-containing protein", "aln": "----MSQTEASKTPKIPDSEPDGSKGKGKQ--------------------------------------------------QLETYRVYVVTWNVGSRFPDNISLRHLLGLQDVTVDKDTKETNAHLPDIYALGLQEVNAQPQQQVLGLFKEDPWTHKAKELLRNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAFQVLQERLPAFPPTFKFREGTSEYDL------------KRRPAWTDRIMYAVQPLNRQPGMQLS------------------IEQCSYKSHPLYTISDHKPVTSDFTIKLYPNVRAPGVVFSPLSLWKIGDENTVEYHKQAEFDEGSNDWIGIFPSEYASLADYVAYEYVNQAESPSSSDSNHQPDPFETPSHHRRGRHHHRNRQRQRRHQEANAQELVRLDFADDVELRHGEQYLLIYFRSTGVRGVTSLAGVSGVFVAEKRHGSPHRTEYHVDXLAEALDIFIL----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ::******.: * .: ** *: . *:* :****:. . : . :*.*: : * : :. :***:** .* : :*: .:: :.. **: * *****.:.: :.:** :.:: .**..* :*::.:.:**: . .: **. ::****:***::. . *:: : . * :*** ::: : :: ::* * **:** :.:** **:*** ***:: :: . : * *: * ******* . * ::* .* : . . *. : : * * ... ****:: : **::* :* : : : :: :: : . : :* *: .. : .:.*:* * . . : * : ", "identical_positions": 102, "similar_positions": 138, "identity": "16.8%" }, { "cls_id": "homologset.agr.HGNC:33888", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BLB8-1", "uniprot_id": "AN34C_MOUSE", "id": "Q8BLB8-1", "name": "Ankyrin repeat domain-containing protein 34C", "aln": "MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRQSPPLCTTPSDVELKTSGLASPPSEKDDDFFILQTGHQSGCSTS-KVLNEPGSPTRKVSSLKRARLPQLKRLQSEPWGLIAPSVLAAATRQDETHGTSTDNEVIRSINDVTFPKRGPLSRTNSIDSKDPTLFPTVQEQVLKVSAS--TPASWKAAYEKGQAPHPRLARRGTLPLDQEKSGMCPPGPSTLKDPASLKLLENDLYDLDIQPVGDPPNSMSLESGKGPLDRKKLNSSHLSLFHGSRESLEVVPSTS-PTSVRRRPPHLLERRGSGTLLLDRIAHTRPGFLPPLNVNLNPPIPDIRASSKPASPLASGLKSMAPVAPNSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZI64-1", "uniprot_id": "D3ZI64_RAT", "id": "D3ZI64-1", "name": "", "aln": "MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRQSPPLCATPSDVELKASGLSSPPSEKDDDFFILQTGHQSCCSTS-KVLNEPGSPTRKVSSLKRARLPQLKRLQSEPWGLIAPSVLAAAARQDETHGTSTDNEVIRSINDLSFPKRGPLSRANSIDSKDPTMFPTVQEQVLKVSSS--TPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMCPPGPSTLKDTASLKMLENDLYDLDIQPGGDPPNSMSLESGKGPLDRKKLNSSHLSLFHGSRESLDAVPSTS-PSSVRRRPPHLLERRGSGTLLLDRIAHTRPGFLPPLNVNLNPPIPDIRASNKPASPLASGLKSMVPVAPNSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C6C1-1", "uniprot_id": "AN34C_HUMAN", "id": "P0C6C1-1", "name": "Ankyrin repeat domain-containing protein 34C", "aln": "MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHSPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTS-KAVNEPGSPTRKVSNLKRARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNSIDSKDPTLFHTVTEQVLKIPVSS-APASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPSGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRESLDTVPSTS-PSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSSKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC31-1", "uniprot_id": "F1QC31_DANRE", "id": "F1QC31-1", "name": "", "aln": "-MADVLELRTDGNSLLKAVWLRRLRLTRLLLEGGAYINESNDRGETPLMVACMSKHSDQQSVSKAKLVKYLLDNKADPNIQDKAGRSALMHACSHRAGHEVVSLLLTNGADPSLEDRHGSSALVYAVNADDKETLKVLLDACKAKGKEVIIITTDKSPSGTKTTKQYLNVPPSPELDERATPAPCASPSEIDLHASPSPSKEEEK-DTVFNFQTKFKSTSSTAAKLPNGLTSPSKKPANPKRARLPQLKRLQSEPWGLIAPSVLAAAN--EESKRANSDEDVVAGVNGLSLSRRGTLSRHNSVDGKD-ILFPMMGDQNTKISPTSSLPPSSKASYERSLAQHQPLARRSTVPTEQEASGVN-FGPASLRDTVHRRRLGTEHYDSDSQLYSD---SSMLDSPKAPLERRKLNTSPLAMLTGSRESLDSNPSTSSPSTARCRAPGLLERRGSGTLLLDYISHTRPGHLPPLNVNPNPPIPDIGASSKPSSPLAAGIRLIAPVAPNSPKRGNLRTKKKLVRRHSMQVEQMKQLSNFEELNHQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *************** ********************:***.*****::** ****:**:*:*******:********:*::**:*** :*** ******* ********** *:******:*****::** ********************.****************::::* :*. *::**:::*:: * ** * .* :*: . * ..*: * * **::* :. **************************: :*:: :.:*::*: .:..:::.:**.*** **:*.** :* : :* *:. : *.* **:**:. * * ****.*:* :** .*: **::*::.. : * .: ** * * * * *:* *.**:*:***:* *::: ******: **** *::.* *.* ************* *:*****.******* ******* :*.**:..**:*:: :.****.**** :**:****:******:*******:***: ", "identical_positions": 327, "similar_positions": 120, "identity": "60.56%" }, { "cls_id": "homologset.agr.HGNC:3389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54756-1", "uniprot_id": "EPHA5_HUMAN", "id": "P54756-1", "name": "Ephrin type-A receptor 5", "aln": "--MRGSGPRGAGRRRPPS--GGGDTPITPASLAGCYSAP---------------------RRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPIHT------YQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRN--IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNA-ISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQY--------------------------------VSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSY--TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPV-FAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGR-ASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG--KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54757-1", "uniprot_id": "EPHA5_RAT", "id": "P54757-1", "name": "Ephrin type-A receptor 5", "aln": "--MRGSGPRGAGRRRTQGRGGGGDTPRVPASLAGCYSAP---------------------LKGPLWTCLLLCAALRTLLASPSNEVNLLDSRTVLGDLGWIAFPKN-GWEEIGEVDENYAPIHT------YQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDENGRN--IKDNQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDDPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHSQTCSKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNA-ISNVNETSVFLEWIPPADTGGGKDVSYYILCKKCNSHAGVCEECGGHVRYLPQQIGLKNTSVMMADPLAHTNYTFEIEAVNGVSDLSPGTRQY--------------------------------VSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSY--TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPV-FGASNDQSQIPIIGVSVTVGVILLAVMIGFLLSGSCCECGCGR-ASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPTQAVHEFGKEIEASCITIERVIGAGEFGEVCSGRLKLPG--KRELPVATKTLKVGYTEKQRRDFLSEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKLIRNPSSLKTLVNASSRVSTLLAEHGSLGSGAYRSVGEWLEATKMGRYTEIFMENGYSSMDAVAQVTLE----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60629-1", "uniprot_id": "EPHA5_MOUSE", "id": "Q60629-1", "name": "Ephrin type-A receptor 5", "aln": "--MRGSGPRGAGHRRTQGRGGGDDTPRVPASLAGCYSAP---------------------LKGPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPIHT------YQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDENGRS--IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAIFPDTITGADSSQLLEVSGSCVNHSVTDDPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSY--TIIKSKETSITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASNDQSQIPIIAVSVTVGVILLAVMIGFLLSGSCCDCGCGR-ASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG--KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSSSDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKLIRNPSSLKTLVNASSRVSTLLAEHGSLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMSSLQEMKVQMVNGMVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAH-ADQVVLLDT-TREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQNS---DVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFK-SPEVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD-GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 362, "similar_positions": 254, "identity": "32.55%" }, { "cls_id": "homologset.agr.HGNC:33891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V0F0-1", "uniprot_id": "RIMB3_MOUSE", "id": "Q3V0F0-1", "name": "RIMS-binding protein 3", "aln": "MTKDSPTPLGGGRASPKKPSSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLRESAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAEMRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQATHSLEEPPLEAQSNTGGTPKPARRLGSLESLNTGVRVHS-------------PNDLLPTRAGSLESLATAHSCSLDNTLNCSQASESEVRAPATSASIPDTS------SPQPPPQLPSIHRKPNDLQK-ESSENKPCEASTSSPPGLDYQELVRQNSELAEALQVLVRRCCDLREENLHLRRKGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPVPGESLEGLDLSQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADAGRPSTPSEITRHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHTRQRQELEATSLLAEQLLQQEGYAQDRRQQLQHYKNKALSDLRTSGKEMQGLQFQPGHPSET-SETTQASESQARDSGRPTFKTKSEERVLPLPTRDIQPPACLSQQENPVIVEEPAAGPQVSDRNSTSQSLDSKPQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIIPKLKLFLARSSYNPFEGPSEHCQGKLPLTAGDYVYVFGDMDEDGFYEGELVNGQRGLVPSNLVEPISGSPILNHLFLKSPDIGPTALPAGHSKVLKKGSLLLGEVQ---ERGLCQVGRVDSKTDMAAESLKTKTEACWLGLKSSLEEQSFSRPLLEAKGAFCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTCYRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPPLDVLVEHHAS-PGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVADATAGNTLLEFSQLQVPLSCQKVSVRTMSLYGESLDSVPAQIPEDFFSCCPFLGAPPFNYTDGNP------FPVCHQKLVQASLGAKSSPRGPGNCGEPQAKFLEAFPEEHPRKHLSLSSLSSDG------TNSQAQGPTEAWKGYEKDLSFQKSPQNHKPPLLFGQSGVEEGHAPHICISGSPAPGFVHLSSEIGHGKIRCWEKPGLEKALLQNQYAPMVPPHQQGSSQCQPADFHHVFEE-KEALCLDSQGTEKPEQRKNKSQNGQRQGTPGSKREC------SVLCPAPTNKVIKMTSGSPDQLETDANNPVRVFLALFDHSPLVISVNSEAAEEELAFQKGQLLRVWGSLDLHGFYHGECNGHLGKIPGHLVVEVEVGTQQTDGRWHLPAQGHLLSETQREDLEGLTNSQGS-YMPQGNSRTPTLWTPKTMVAALDYDPRDGRAGVQAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7Z1-1", "uniprot_id": "D4A7Z1_RAT", "id": "D4A7Z1-1", "name": "", "aln": "MTKDSPTPLGGGRASPKKPGSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLREAAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAELRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQTTHSLEEPPLEAQSNTDGTPKPARRLGSLESLNTGVRVHS-------------PNDLLPTRASSLESLATAHSCSLDNTLNCPETSESEVRAPSTTASIPDTS------SPQPPPQLPSKHRKPNDLQK-ESSENKPCEDSTSSSPGLDYHELVRQNSELAEALQVLVRRCCDLREENLQLRRTGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPMPGESLEGLDLGQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADTGSPSAPSEIARHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHARQRQELEATGLLAEQLLQQEGYAQDRRQQLQQYQNKTPSDLRISGKEMQGLQFQPGHPSES-SETTQASESQVRDSRRLKFKTKSEEYILPLPTRDIQPPACLSQQENPVALGEPAAASQVSDRNPSSQSLDSKLQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIVPKLKIFLARYSHNPFEGPSERSHDELPLTAGDYVYVFGDVDEDGFYEGELVNGQRGLVPSNLVEPISGSPILSHLFLKSPGAGPTSLPAEHSKALKKGSLLLGEVQ---ERGLCQAGRVDSKTDVASESLKTKTEACWLGLKSSMEEQSFSRPLLEAKGALCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTRYQVRVGVQLPRDLLQVLWETMSSTVTFDTPLAGPPDPPLDVLVEHHAASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVANATAGNTLLELSQLQLPLGCQKVSVRTMSLYGESLDSVPAQIPEDCFSCYPFLEAPPFNYTDGDP------FPVCHQKLAQASLSAKSSPHVPGSCGEPQAKFLEAFSEEQPRKHLSLSSLSSDG------ANKQVQGPTEAWKGYEKDLSFQRSPQNHKPPLLFGQSGVEEGHAPHICISGSPSPGFIHLSSEVGPGKILCWEEPGLEKALLQNQYAQMVPHHQQGSSQCHTADFHHIFEE-KEALCLDSRCTEKPEQRK-KSQNGQRQGTPGSKRECQFHEPTSVLCPAPTSKIIKIASGGSDQLETDGNSPVRVFLALFDHSPLARSVNSEATEEELSFQKGQLLRVWGSRDHHGFYHGECNGQVGKIPGHLVVEVEVGTQQTDGRWLLPPQGHLHSEAQREDLEGLTNSQGS-YMLQGNSRTPTLWTPKTMVAALDYDPRDGRAGVRAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNM3-1", "uniprot_id": "RIM3B_HUMAN", "id": "A6NNM3-1", "name": "RIMS-binding protein 3B", "aln": "MAKDSPSPLG---ASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLG--RACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLS-----KKTSSQSNSSSE-GSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLEVLVERHAS-PGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLTIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:****:*** ******....*******:*************.*** *:******:: ***** **:**:****:*******:* *********:****************** ********:*** *:***********:******:***.****.************** ***:**********:*****:*********** *** :***.*..***:.****** ::.*.: :**** :****:**.: * *:* *:.**.*:*.**:.:*.* * ***.* . .::*:** *..:. :* *.: ** *** ** *** .: : *.**.:*** *.*.***.::**:: * **:** **.*** *:*** :*** * . :*.**** ****:****.**:** ****:********:***:**** **:* ***: ***:******.* *** *** **:********:*:. *. *. .*..*:** *: ******************** *:*.:.***.::* *:..* .*:*: ******. :****:**..***.*.** **:*:****** *.* *:***.**** ::*::*: ***:* : . * ** :*:.*:******* . .***:****: :*: .**: * **:*.** :****.* **:* .***.:.* * .*:::.*: :. *.**** * :*.** : *.*: .***: .:**.*. ************ ********. :** *************:* .*** . ** ****:*:*: .:******.:: ..:********:*:***:********** :*:*******:** *..* * . * ***. **: *** :.:.*::.*** *:.* :***** **.***::*:* *.****** *** .*: :*.:***** :**.: :***:*:*********.***. .*:*:********.** ***:**. ****** *** *:*** *:** ***** * * ***:**** ***** ***:****:**: ******************************.**:** ***:****.*:**:****:** ********** ************** * * : :***.** *:* **** *** *. .**:**: **.************ ** **:: .:*.*.*:* :..*.* :***:* .*** **:*****:** : .*.* :*. *: * **:***:** :* * * * *:..**:.* *:* * .. * *:** .:***::::* :****** : **: *:*: . :.:: : * ** * *.*****: *:**:. *..:** *..*.*.***:** *:.**. *.* :*:**** *** ******** * *.** .*** ::*:***:**.*:****:*** ** *.**** * :: **::*** .*** : ****: .***** *:******* **: * :.**:*.******* ****:**:****** *************.:.:**.", "identical_positions": 997, "similar_positions": 363, "identity": "60.39%" }, { "cls_id": "homologset.agr.HGNC:33892", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V0F0-1", "uniprot_id": "RIMB3_MOUSE", "id": "Q3V0F0-1", "name": "RIMS-binding protein 3", "aln": "MTKDSPTPLGGGRASPKKPSSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLRESAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAEMRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQATHSLEEPPLEAQSNTGGTPKPARRLGSLESLNTGVRVHS-------------PNDLLPTRAGSLESLATAHSCSLDNTLNCSQASESEVRAPATSASIPDTS------SPQPPPQLPSIHRKPNDLQK-ESSENKPCEASTSSPPGLDYQELVRQNSELAEALQVLVRRCCDLREENLHLRRKGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPVPGESLEGLDLSQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADAGRPSTPSEITRHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHTRQRQELEATSLLAEQLLQQEGYAQDRRQQLQHYKNKALSDLRTSGKEMQGLQFQPGHPSET-SETTQASESQARDSGRPTFKTKSEERVLPLPTRDIQPPACLSQQENPVIVEEPAAGPQVSDRNSTSQSLDSKPQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIIPKLKLFLARSSYNPFEGPSEHCQGKLPLTAGDYVYVFGDMDEDGFYEGELVNGQRGLVPSNLVEPISGSPILNHLFLKSPDIGPTALPAGHSKVLKKGSLLLGEVQ---ERGLCQVGRVDSKTDMAAESLKTKTEACWLGLKSSLEEQSFSRPLLEAKGAFCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTCYRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPPLDVLVEHHAS-PGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVADATAGNTLLEFSQLQVPLSCQKVSVRTMSLYGESLDSVPAQIPEDFFSCCPFLGAPPFNYTDGNP------FPVCHQKLVQASLGAKSSPRGPGNCGEPQAKFLEAFPEEHPRKHLSLSSLSSDG------TNSQAQGPTEAWKGYEKDLSFQKSPQNHKPPLLFGQSGVEEGHAPHICISGSPAPGFVHLSSEIGHGKIRCWEKPGLEKALLQNQYAPMVPPHQQGSSQCQPADFHHVFEE-KEALCLDSQGTEKPEQRKNKSQNGQRQGTPGSKREC------SVLCPAPTNKVIKMTSGSPDQLETDANNPVRVFLALFDHSPLVISVNSEAAEEELAFQKGQLLRVWGSLDLHGFYHGECNGHLGKIPGHLVVEVEVGTQQTDGRWHLPAQGHLLSETQREDLEGLTNSQGS-YMPQGNSRTPTLWTPKTMVAALDYDPRDGRAGVQAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7Z1-1", "uniprot_id": "D4A7Z1_RAT", "id": "D4A7Z1-1", "name": "", "aln": "MTKDSPTPLGGGRASPKKPGSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLREAAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAELRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQTTHSLEEPPLEAQSNTDGTPKPARRLGSLESLNTGVRVHS-------------PNDLLPTRASSLESLATAHSCSLDNTLNCPETSESEVRAPSTTASIPDTS------SPQPPPQLPSKHRKPNDLQK-ESSENKPCEDSTSSSPGLDYHELVRQNSELAEALQVLVRRCCDLREENLQLRRTGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPMPGESLEGLDLGQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADTGSPSAPSEIARHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHARQRQELEATGLLAEQLLQQEGYAQDRRQQLQQYQNKTPSDLRISGKEMQGLQFQPGHPSES-SETTQASESQVRDSRRLKFKTKSEEYILPLPTRDIQPPACLSQQENPVALGEPAAASQVSDRNPSSQSLDSKLQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIVPKLKIFLARYSHNPFEGPSERSHDELPLTAGDYVYVFGDVDEDGFYEGELVNGQRGLVPSNLVEPISGSPILSHLFLKSPGAGPTSLPAEHSKALKKGSLLLGEVQ---ERGLCQAGRVDSKTDVASESLKTKTEACWLGLKSSMEEQSFSRPLLEAKGALCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTRYQVRVGVQLPRDLLQVLWETMSSTVTFDTPLAGPPDPPLDVLVEHHAASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVANATAGNTLLELSQLQLPLGCQKVSVRTMSLYGESLDSVPAQIPEDCFSCYPFLEAPPFNYTDGDP------FPVCHQKLAQASLSAKSSPHVPGSCGEPQAKFLEAFSEEQPRKHLSLSSLSSDG------ANKQVQGPTEAWKGYEKDLSFQRSPQNHKPPLLFGQSGVEEGHAPHICISGSPSPGFIHLSSEVGPGKILCWEEPGLEKALLQNQYAQMVPHHQQGSSQCHTADFHHIFEE-KEALCLDSRCTEKPEQRK-KSQNGQRQGTPGSKRECQFHEPTSVLCPAPTSKIIKIASGGSDQLETDGNSPVRVFLALFDHSPLARSVNSEATEEELSFQKGQLLRVWGSRDHHGFYHGECNGQVGKIPGHLVVEVEVGTQQTDGRWLLPPQGHLHSEAQREDLEGLTNSQGS-YMLQGNSRTPTLWTPKTMVAALDYDPRDGRAGVRAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NJZ7-1", "uniprot_id": "RIM3C_HUMAN", "id": "A6NJZ7-1", "name": "RIMS-binding protein 3C", "aln": "MAKDSPSPLG---ASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLG--RACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLS-----KKTSSQSNSSSE-GSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHAS-PGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:****:*** ******....*******:*************.*** *:******:: ***** **:**:****:*******:* *********:****************** ********:*** *:***********:******:***.****.************** ***:**********:*****:*********** *** :***.*..***:.****** ::.*.: :**** :****:**.: * *:* *:.**.*:*.**:.:*.* * ***.* . .::*:** *..:. :* *.: ** *** ** *** .: : *.**.:*** *.*.***.::**:: * **:** **.*** *:*** :*** * . :*.**** ****:****.**:** ****:********:***:**** **:* ***: ***:******.* *** *** **:********:*:. *. *. .*..*:** *: ******************** *:*.:.***.::* *:..* .*:*: ******. :****:**..***.*.** **:*:****** *.* *:***.**** ::*::*: ***:* : . * ** :*:.*:******* . .***:****: :*: .**: * **:*.** :****.* **:* .***.:.* * .*:::.*: :. *.**** * :*.** : *.*: .***: .:**.*. ************ ********. :** *************:* .*** . ** ****:*:*: .:******.:: ..:********:*:***:********** :*:*******:** *..* * . * ***. **: *** :.:.*::.*** *:.* :***** **.***::*:* *.****** *** .*: :*.:***** :**.: :***:*:*********.***. .*:*:********.** ***:**. ****** *** *:*** *:** ***** * * ***:**** ***** ********:**: ******************************.**:** ***:****.*:**:****:** ********** ************** * * : :***.** *:* **** *** *. .**:**: **.************ ** **:: .:*.*.*:* :..*.* :***:* .*** **:*****:** : .*.* :*. *: * **:***:** :* * * * *:..**:.* *:* * .. * *:** .:***::::* :****** : **: *:*: . :.:: : * ** * *.*****: *:**:. *..:** *..*.*.***:** *:.**. *.* :*:**** *** ******** * *.** .*** ::*:***:**.*:****:*** ** *.**** * :: **::** .*** : ****: .***** *:******* **: * :.**:*.******* ****:**:****** *************.:.:**.", "identical_positions": 997, "similar_positions": 362, "identity": "60.39%" }, { "cls_id": "homologset.agr.HGNC:33893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP38-1", "uniprot_id": "D3ZP38_RAT", "id": "D3ZP38-1", "name": "", "aln": "--MPEDIDFDGQTLNT-----SEQPHWYWRLWTCCLGYG--------CLDYQVDEYPVYLIPYEPVGQFQKAASMGDLSTVEHFITSRRYHVDKYDRRNRTSLHYACAHNHPEVVMLLIKSNCTINAQDDEGCTPLIKATERNNLECVSILLKHGADPHMADFTGNTALHYAVYNGNRAIASELLKYKVDINAITKHGFTPFSLAVFEKREKMAEFLTERGADVHEVIESNSEETSFKQPEQRSKKHIRFNEEVHYNTGLKPCCSELRPPEQLKSILKKPDQISTEVDNNMEEKSLSRLPDKPDPDIPGPTTENNDSISIIKKVSKDPEININNTECISIKTSSRFLHQSKLVRRVENRVRKLLGRHEVNVCSQGEPLPITSEGKTPIKNLSTDSAIEMLDRESVPLRLPPEDNSDDMLLVQKNTQGDNPIQKETPKLVCRLSRKTEVNVTLEEKILPSTSEGKTYSMYLKERLKERMKEGTENSESDTSDEEPFPSTSAGRTHSMKMTEKKKEHEGKDAYMHSRHSSVKRNEYIKEQADWRHEQLKGLLKN-DIKEILMEQLATEQARMRKLLREDVRKTSELLRNELRQMCVEQVALLQAHVTETQQEQDLFRRDLKEVVHEQSKKSIICPKEKPLPGPFKGTADLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6S8J7-1", "uniprot_id": "POTEA_HUMAN", "id": "Q6S8J7-1", "name": "POTE ankyrin domain family member A", "aln": "MVAEVSPKLAASPMKKPFGFRGKMGKWCCCCFPCCRGSGKNNMGAWRDHDDSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFG------------------------------------RTALILAVRCGSASIVSLLLQQNIDVFSQDVFG----------------------QTAEDYAVSS---------------HHSIICQLLSDYKENQMPNNSSGNSNPEQDLKLTSE--------------------EEPQRLKGSENSQ----HEKVTQEPDINKDCDREVEEEMQKHGSNNVGLSENLTDGAAAGNGDGGLVPQRKSRKHEN------------QQFPNTEIEEYHRPEKKSNEKNK------VKSQIHSVDNLDDITWPSEIASEDYDLLFSNYETFTLLIEQLKMDFNDSASLSKIQDAVISEEHLLELKNSHYEQLTVEVEQMEN--------------MVHVLQK----------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: ...::. .: :* :.** * * * .. * * : * :*::::** *::. .: :: * ::* *:::**:** ***:.:.*** **:. :* ::. *.: *.****.: :: **. :**:**:**::.*: *********** :: :*. ** * .**:: .* *:**: ***. ::::*.:** :: *::: : . . *.. * ... :* :::*:: * . : :.::* :. *:* : : :.: .: : .:. . .. : * :*** . * ** .:**: :* ** : :. :: .:.:: . ** *.*:: .:: *: . : :* ..: :: : **.*. . * : ..::*:: ::*: **.. : *. :: *: . *:.* : :*:*** : .* : : ** **:: **::: :: : :** .* ", "identical_positions": 124, "similar_positions": 193, "identity": "19.11%" }, { "cls_id": "homologset.agr.HGNC:33894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925S8-1", "uniprot_id": "YMEL1_RAT", "id": "Q925S8-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTVPLSHLINAFHSPKNISVSVNTSASPKQHRDTVAEHEAPSSEPVLNLRDLGLSELKIGQIDKLVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLQSICSDLQNFPVFIQSRGFKTLKSRTRRLQSTSERLAEAQNIAPSFVKGFLLRDRGTDLESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIEFPMHPYSRQTIIQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNEIRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RU33-1", "uniprot_id": "POTEC_HUMAN", "id": "B2RU33-1", "name": "POTE ankyrin domain family member C", "aln": "------MVTEVCSMPAASAVKKPFDLR------SKMGKWFHHRFPCCKGSGKSNMGTSGDHDDSFMKMLRSKMGKCCHHCFP---------CCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGAWGDYDDS---AFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSE---VVQLLLDRRCQLNVLDNKKRTALIKAVQCQE-----DECVLMLLEHGADQNIPDEYGNTTLHYAVHNEDKLMAKALLLYGADIESKN----------KCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVS------SQDLSGQTAREYAVSSH-HHVICELLSDYK----EKQMLKISSENSNPEQDLKLTSE---EESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVG--LPENLTNGASAGNGDDG-----------------LIPQRRSRKPENQQFPDTENEE----------------------------------YHSDEQNDTRKQLSEEQNTGIS----------QDEILTNKQKQIEVAEKKMN---SELSLSHKKEEDLLREN--------SMLQEEIAMLISGDWN-------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::* : :: .. : .. .. :** . .: .. *. . . :* .: :: .::.* .: :* .* :. .. : ::. ..:. : : .. : .* * *:: : : :* ::.* : :. ::* .* . *.::: *.**::. ** :* : :. : . :* : :. *. :** ** * : :: :.. : .: . . . :: ...:. * : :* :* : * **:* : :: : :*:: * : * *:: * **: * :.:.. . * * . *:.: .: ::.* :**:: . :: :: *.: * * * : . : .: . :: : : . *:.*: ** :*: .. ***.* *: . ** : *:*** : :*:: . * .* ..*. *: * ** : :..:. *.* *. ..::: * * : :::.:*.* :. * :::** :*: .:: ", "identical_positions": 90, "similar_positions": 210, "identity": "12.59%" }, { "cls_id": "homologset.agr.HGNC:33895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10987-1", "uniprot_id": "ACT1_DROME", "id": "P10987-1", "name": "Actin-5C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6S8J3-1", "uniprot_id": "POTEE_HUMAN", "id": "Q6S8J3-1", "name": "POTE ankyrin domain family member E", "aln": "MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSKMGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVPSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::.*.**:*****************************:**:* ** **:****.**************:****:**************************:************************************ ***:********:******:******** ***** ********:*.************ *** *************************************************************.*****:*******:*****.*********:*************:*.******:***** ***:*****:******:**********************************", "identical_positions": 338, "similar_positions": 28, "identity": "31.44%" }, { "cls_id": "homologset.agr.HGNC:33896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FH89-1", "uniprot_id": "F7FH89_RAT", "id": "F7FH89-1", "name": "", "aln": "---------MSFSMKKIFGAKEKT--------------------PLGFCDAPQMTVSEFFFG----------------------DNPN-----------------------------------------YPKYHTTYRPLGHIHRVAAEGDAAQMEILITLGQCSVSDRDRKDRTALHFACVYGRLPVVTVLVNNNCEIDAFDKNHITPLIKSVQCWKQKCATLLLEHGADPNVIDSSGNSALHYAVYNGHEEMVALLLQYKANIEQKTKDGFTPLLLALREKRVEVAELLVRMGADVHVVDELQRNTLIYAIRCGSKGLAVSLLKKGIDFFYKDVFGWTALRYAIEGHCTFRQTLLDFEENLHSRKENEPELEVEPNPSCILAEQVDAGDDSLARVSSCLSPVTPVLALKDEENSRHTGSNSESEPPNCSGNSPAATDKIFGNRGKRTVEAWVEKDPSSKSATEMRDSVTNEAVERIELFTSTSEPELELMSIEEGISDESENDQPLSELEHLPQIKVEHLSGAGYQVEKININGQMKGRNSILLKIYVITYLPKTGHCHMTLKYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6S5H5-3", "uniprot_id": "POTEG_HUMAN", "id": "Q6S5H5-3", "name": "POTE ankyrin domain family member G", "aln": "MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCRHCFPWCRGSSKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSKVGPWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLS-----------------------------DYKEKQMLKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEEMS------QEPEINKGGDRKVEEEMKKHGSTHMG--FPENLPNGATA--DNGDDGLIPPRKSRTPESQQFPDTENEQYHSDEQNDTQKQLSEEQNTGILQDEILIHEEKQ------IEVAENEF--------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:** ** :.* . * * . *.. . :* *: : *:**. . *.::**.* *...: :::: * : .:..:*::.*****:*.. *. **.:*::..*::: :*::: *.* *:*** :::** :*****:***: *. **:*****:** .: *. ** * *:**.*.*.*:*****.::*:: :*.::*:: *:::.:*. *.:** *: *** .:. **::.**. :*: * ** .**:..* .. **. * :..: :*** * * *..**:*:: ...:*:* : * : :.: *.*.** ::*. *:: . : :.:.* *. : . * : : *. ::**:* *: :: .* ::.. ..:* ::* *: : : ::: : ", "identical_positions": 130, "similar_positions": 170, "identity": "22.93%" }, { "cls_id": "homologset.agr.HGNC:33898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08632-1", "uniprot_id": "KR195_MOUSE", "id": "O08632-1", "name": "Keratin-associated protein 19-5", "aln": "MSYYGSYYGGLGSGIRGFGNLGYGYGCGCG-FGGYGYGSGYGRYGYGYPRPLYYGGYGFSRFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3LI54-1", "uniprot_id": "KR198_HUMAN", "id": "Q3LI54-1", "name": "Keratin-associated protein 19-8", "aln": "MSYYRSYYGGLGYGYGGFGGWGYGYGCGYGSFRRLGYGCGYGGYGFSCCRPLYYGGYGFSAFY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ******* * ***. ******* * * ***.*** **:. *********** **", "identical_positions": 45, "similar_positions": 4, "identity": "71.43%" }, { "cls_id": "homologset.agr.HGNC:339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHG3-1", "uniprot_id": "APJ_RAT", "id": "Q9JHG3-1", "name": "Apelin receptor", "aln": "------MEDDG--YNYYGADNQSECDYADWTPSGALIPAIYILVFLLGTTGNGLVLWTVFWSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYREFDWPFGTFSCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAVPVMVFRSTDIPENSTKTQCYMDYSMVATS-NSEWAWEVGLGVSSTAVGFVVPFIIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGNLLHWP--CDFDSFLMNVFPYCTCISYVNSCLNPFLYAFFDPRFRRACTSMLCCDQSGCKGSPHSSSAEKSASYSSGHSQGPGPNMCKGGEPMHEKSIPYSQETLVD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV08-1", "uniprot_id": "APJ_MOUSE", "id": "Q9WV08-1", "name": "Apelin receptor", "aln": "------MEDDG--YNYYGADNQSECDYADWKPSGALIPAIYMLVFLLGTTGNGLVLWTVFRTSREKRRSADIFIASLAVADLTFVVTLPLWATYTYREFDWPFGTFSCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAVPVMVFRSTDASENGTKIQCYMDYSMVATS-NSEWAWEVGLGVSSTAVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWP--CDFDIFLMNVFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLCCDQSGCKGTPHSSSAEKSASYSSGHSQGPGPNMGKGGEQMHEKSIPYSQETLVD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35414-1", "uniprot_id": "APJ_HUMAN", "id": "P35414-1", "name": "Apelin receptor", "aln": "------MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATV-SSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWP--CDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGKGGEQMHEKSIPYSQETLVVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SZP9-1", "uniprot_id": "APJA_DANRE", "id": "Q7SZP9-1", "name": "Apelin receptor A", "aln": "MEPTSEYTETY--DYYDTGYNDSGCDYSEWEPSYSLIPVLYMLIFILGLSGNGVVIFTVWR-AKSKRRAADVYIGNLALADLTFVITLPLWAVYTALGYHWPFGVALCKISSYVVLVNMYASVFCLTCLSFDRYLAIVHSLSSGRLRSRATMLASLGAIWFLSCLLAVPTLLFRTTVDDTGSNRTTCAMDFSLVTLNQDHESLWIAGLSLSSSALGFLLPFLAMTVCYCFIGCTVTRHFSHLRKEDQKKRR-LLKIITTLVVVFAFCWTPFHVLKSMDALSYLDLAPNSCGFLHFLLLAHPYATCLAYVNSCLNPFLYAFFDLRFRSQCLCLLNLKK-----AMHGHMSSMSSTLSAQT----------------QKSEVQSLATKV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0T2N3-1", "uniprot_id": "APJB_DANRE", "id": "A0T2N3-1", "name": "Apelin receptor B", "aln": "MNAMDNMTADYSPDYFDDAVNSSMCEYDEWEPSYSLIPVLYMLIFILGLTGNGVVIFTVWR-AQSKRRAADVYIGNLALADLTFVVTLPLWAVYTALGYHWPFGVALCKISSYVVLLNMYASVFCLTCLSLDRYMAIVHSLTSTQLRTRGHMRASLTAIWLLSGVLAAPTLLFRTTVYDVETNRTSCAMDFNLVVSQPGQETYWIAGLSISSTALGFLIPLLAMMVCYGFIGCTVTRHFNSLRKEDQRKRR-LLKIITTLVVVFAACWMPFHVVKTMDALSYLNLAPDSCTFLNLLLLAHPYATCLAYVNSCLNPLLYAFFDLRFRSQCLCLLNLKK-----ALH---ASPASSLSSQ------------------KTEAQSLATKV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *.* *:* :* .* :***.:*:*:*:** :***:*::**: ::.***:**::*..**:******:******.** :.****. **:***::::********** **:***:***:.::. :** * .: .:*.*: :** *.:::*:* .: * **:.:*. . * * .**.:**:::**::*: * .** **. *:: ** * *. :*** **.**..***.** ** *:*::*:: *. * * * * :*: .**.**::********:****** *** * .:* : : * .. ::: *: *: * * * ", "identical_positions": 154, "similar_positions": 106, "identity": "39.59%" }, { "cls_id": "homologset.agr.HGNC:3390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54759-1", "uniprot_id": "EPHA7_RAT", "id": "P54759-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVVQTRYPSWIILCYIWLLGFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPSGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN--IRENLYVKIDTIAADES-FTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAVFPDTVTGSEFSSLVEVRGTCVSSAEEEAENSPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRRFYKSSSQDLQCSRCPTHSFSDREGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNL-IFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQR-----LFAAVS------------------ITTGQAAPSQVSG------VMKERVLQRS---VELSWQEPEHPNGVITEYEIKYYEKDQRERT-YSTLKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEASGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPSSLKTPLGTCSRPISPLLDQSTPDFTAFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIDDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61772-1", "uniprot_id": "EPHA7_MOUSE", "id": "Q61772-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVVQTRFPSWIILCYIWLLGFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPSGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN--IRENLYVKIDTIAADES-FTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIVENLAVFPDTVTGSEFSSLVEVRGTCVSSAEEEAENSPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRRFYKSSSQDLQCSRCPTHSFSDREGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNL-IFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQR-----LFAAVS------------------ITTGQAAPSQVSG------VMKERVLQRS---VQLSWQEPEHPNGVITEYEIKYYEKDQRERT-YSTLKTKSTSASINNLKPGTVYVFQIRAVTAAGYGNYSPRLDVATLEEASGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKMIRNPSSLKTPLGTCSRPLSPLLDQSTPDFTAFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIDDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15375-1", "uniprot_id": "EPHA7_HUMAN", "id": "Q15375-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN--IRENLYVKIDTIAADES-FTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNL-IFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQR-----LFAAVS------------------ITTGQAAPSQVSG------VMKERVLQRS---VELSWQEPEHPNGVITEYEIKYYEKDQRERT-YSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2N6-1", "uniprot_id": "A0A8M9P2N6_DANRE", "id": "A0A8M9P2N6-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVCTSVSCVWIIFC-LHLCFYVNTGIAQNTREVILLDSKAQQTELEWISSPPSGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWIEKGDAQRIFVELKFTLRDCNSLPGVVGSCKETFNLYYQETDVEVGRN--IRESQYVKIDTIAADES-FTQGDLGERKMKLNTEVRIIGPLSRRGFYLAFQDVGACIALVSVKVYYKKCWSIIENLATFPDTVTGSEFSSLVEVEGTCVNDAEEEADNSPKMHCSAEGEWLVPIGKCICKAGFHQ--KGDACEPCGRGFYKSSSQDLQCSRCPAHSYNDREGSWRCDCEDGYYRALSDPPSVSCTRPPSAPQNL-LYNINHTTVSLEWTPPADTGGRNDVTYRIICRRCTWEPEECFPCGSNVGYSPQQSGLTDTYVTITDLLAHANYTFEVEAVNGVSDLSRTQR-----LFAAVS------------------IATSQAAPSQVSE------VIKERVQQHS---VQLSWQEPDQPNGVITEYEIKYYEKDQKDRI-YSTVKSKSTSATVNNLKPSTAYVFQIRAFTAAGYGIFGPRLEVTTKEESTG---SATVISSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFQFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVSVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEYMENGSLDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIDDDPEAVYTTTGGKIPVRWTAMEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPPGLHQLMLDCWQKDRADRPKFDQIVGILDKMIRNPNTLKTPMGTCLRPISPLLDQNTPDFTSFRLVSEWLEAIKMERYMDNFTAAGYSSLESVARMTIEDVMSLGISLVGHQKKIMSSIQTMRAQMLHLHGTGVQV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQ----NSDVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYET--PTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSP-EVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQ-------SVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILDGQR-GQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 397, "similar_positions": 318, "identity": "35.35%" }, { "cls_id": "homologset.agr.HGNC:33902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R854-1", "uniprot_id": "M0R854_RAT", "id": "M0R854-1", "name": "Keratin-associated protein", "aln": "-----MSLRGYSRLCSATSHRNHCYIPVTPSIAVCSEDVNPTFGHYLPSSYQGNLWLLDHCQDSYCEAPCCDSPSCVLKTCPAS-SDPTDSCVPCKSPTANQVVSDCKTTNIRCRPSCSPCPGTKGYVSNCTTATRFASKACQTLQNGSRCIEQYNSFLGNLQAPYHCIRGNNEYRSYRNFGFITNGFSPSCYTISSYHPRSYLMRYCQYPNYGSSSFPSRSYLCRNFRSLSCIPSTFPPLRYLCSSNRPLNCY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9A2-1", "uniprot_id": "G3X9A2_MOUSE", "id": "G3X9A2-1", "name": "Keratin-associated protein", "aln": "-----MSLRGYPRLCSATSHRNHCYIPVTPSITVCSDDVNPTFGPYLPSSYQGNLWLLDHCQDSYCEASFCDSPSCVLKTCAPS-CDPTDSCVPCNSLSANQVVSDCETTKIRARPSCSSSTGTKGYVSNCTTATRSASKACQTLQNGSGFIGQFNSFPKNLQAPHHCILGNNGYRSYGNFGFITNGFSPSCYTISSYHPRSYLMRYCQYPNYVPSSFPYRSYLCRNFQSLSRIPSTFPPLRYLCSSNRPLHCY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3LI83-1", "uniprot_id": "KR241_HUMAN", "id": "Q3LI83-1", "name": "Keratin-associated protein 24-1", "aln": "MPAGSMSTTGYPGVCSTTSYRTHCYIPVTSSVTLSSSDLSPTFGHCLPSSYQGNLWLLDYCQESYGEAPTCKSPSCEPKTCSTTGCDPSNSSVPCNSPSAGQVFSVCETTNVSPSPSCSPSTQTNGYVCNCHIPTRNASKACQTLRNGSNCFGQLNCLSKSFQTLNHCRLSTLGYKSYQNPCFIPSYVSPLCYISNSCQPQSYLVRNYHYSSYRPTSCRPLSYLSRSFRSLSYIPSTFPPLRYLCSGSRPLKCY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **. :**:**:*.*******.*:::.*.*:.**** *************:**:** **. *.**** ***..: .**::*.***:* :*.**.* *:**:: ****... *:***.** .** ********:*** : * *.: .:*: ** .. *:** * **.. .** ** .* :*:***:* :*..* .:* ***.*.*:*** *************..***:**", "identical_positions": 137, "similar_positions": 65, "identity": "53.94%" }, { "cls_id": "homologset.agr.HGNC:33904", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWM1-1", "uniprot_id": "D3ZWM1_RAT", "id": "D3ZWM1-1", "name": "Cis-aconitate decarboxylase", "aln": "--MMLKSVTESFASMIHGLRVGHLTDGVIQRSKR------------------------------MILDSLGVGFLGTGTEVFHNVTQYSKIYSSNTSSTVWGRPDFRLPPTYAAFVNGVAIHSMDFDDTWHPAT--HPS---GAVLPVLTALSEALPQTPKFSGLDLLLAFSVGIEVQGRLLH-FSKEAKDIPKRFHPPSVVGTLGSAAATSKFLGLSLTKCREALAIAVSHAGAP----IANAATQTKPLHIGNAAKHGMEATFLAMLGLQGNKQILDLGSGFGAFYANYSPKDLPSLDS---HIWLLDQQDVAFKSFPAHLATHWVADAAAAVRKHLVTSERALLPADHIERIVLRIPDVQYVNRPFPDSEHEAR-HSFQYVACATLLDGSVTVPSFYSQKVNRPQVKELLKKVELEHPPDNLPSFN-----TLYCEISITLKDGTTFTERSDTFYG--HWRKPLSQEDLHKKFRANASKILGEDTVESLITVVEKLEDLEDCAMLTRLLKG--PSVQEEASKLSSIFSFHHTSLPKFTNI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54987-1", "uniprot_id": "IRG1_MOUSE", "id": "P54987-1", "name": "Cis-aconitate decarboxylase", "aln": "--MMLKSVTESFAGMIHGLKVNHLTDGIIRRSKR------------------------------MILDSLGVGFLGTGTEVFHKVTQYSKIYSSNTSSTVWGRPDFRLPPTYAAFVNGVAVHSMDFDDTWHPAT--HPS---GAVLPVLTALSEALPQIPKFSGLDLLLAFNVGIEVQGRLMH-FSKEAKDIPKRFHPPSVVGTLGSAAAASKFLGLSLTKCREALAIAVSHAGAP----IANAATQTKPLHIGNAAKHGMEATFLAMLGLQGNKQILDLGSGFGAFYANYSPEDLPSLDS---HIWLLDQQDVAFKSFPAHLATHWVADAAAAVRKHLVTPERALFPADHIERIVLRIPDVQYVNRPFPDSEHEAR-HSFQYVACASLLDGSITVPSFHSQQVNRPQVRELLKKVKLEHPPDNPPSFD-----TLYCEISITLKDGTTFTERSDTFYG--HWRKPLSQEDLRNKFRANASKMLCRDTVESLITVVEKLEDLEDCSVLTRLLKG--PSVQDEASKLSSMSSFDHTTLPRFTNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NK06-1", "uniprot_id": "IRG1_HUMAN", "id": "A6NK06-1", "name": "Cis-aconitate decarboxylase", "aln": "--MMLKSITESFATAIHGLKVGHLTDRVIQRSKR------------------------------MILDTLGAGFLGTTTEVFHIASQYSKIYSSNISSTVWGQPDIRLPPTYAAFVNGVAIHSMDFDDTWHPAT--HPS---GAVLPVLTALAEALPRSPKFSGLDLLLAFNVGIEVQGRLLH-FAKEANDMPKRFHPPSVVGTLGSAAAASKFLGLSSTKCREALAIAVSHAGAP----MANAATQTKPLHIGNAAKHGIEAAFLAMLGLQGNKQVLDLEAGFGAFYANYSPKVLPSIAS---YSWLLDQQDVAFKRFPAHLSTHWVADAAASVRKHLVA-ERALLPTDYIKRIVLRIPNVQYVNRPFPVSEHEAR-HSFQYVACAMLLDGGITVPSFHECQINRPQVRELLSKVELEYPPDNLPSFN-----ILYCEISVTLKDGATFTDRSDTFYG--HWRKPLSQEDLEEKFRANASKMLSWDTVESLIKIVKNLEDLEDCSVLTTLLKG--PSPPEVASNSPACN----NSITNLS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UYM1-1", "uniprot_id": "B0UYM1_DANRE", "id": "B0UYM1-1", "name": "Cis-aconitate decarboxylase", "aln": "--MIRKSVTDSFGAAVSCLSTSHLTDEVIRRSKR------------------------------MILDTLGVGLIGTRTPVFNTVLQCSQRQQALENSKVWGRPGSSLPPQYAAFVNGVAVHSMDFDDTWHPAT--HPS---GAVLPALLALAETLPVKP--SGLELLLAFNVGIEIQGRLLR-FSKEAHNIPKRFHPPAVVGVMGSAAATAKLLRLPAAQSIAALAIACSSAGAP----MANAATQTKPLHMGNAARGGLEASQLALFGLVGNTHILDLPSGFGSFYPDYVPHPLAEVTPNSHYRWVLEEQDIAQKRFPAHLGMHWVADAAIEARAKFLD-KHPNADLSQIKKITLRVPSSRYVDCPLPVTEHQAR-HSFQFNCCTALLDGEVNVQSFSRAQMNRSVLKELLLKVELENPQDNHSSFQ-----KMYCEITVLSTQGEMFTARCDTFYG--HWRKPLSQEDLLKKFRLNASSVLPNEVLEEIIYAVDHLDTNQDCSKLWSYMHFNKHMVQRDERRCFALA-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12428-1", "uniprot_id": "PRPD_YEAST", "id": "Q12428-1", "name": "Probable 2-methylcitrate dehydratase", "aln": "MFLAKNLKNNKIKVCLPKKKFAALSTASIQTNERPNPDKVLKDIAKYVHETPLKSSLALDTARLCFLDTLGCGLAALKFKQAQNIIKPIVPGTIVPSGTKILGTSYVMDPVKGAFAIGTLIRWLDYNDCWLAAEWGHPSDNLGGILAVADHLSRLNKATHGKNGKQFLVKDVLEAMIKAHEIQGIIALENSFNKVGLDHVVLVKVATAGVVSKMLGLSQEQTIEALSQAFVDGQSLRTYRHAPNTGSRKSWAAGDAVSRAVNLAYLVKNANVGTIPSVLTARTWGFYDVLFKGKPFSFQQRSKYDSYVMEN-VLFKISFPAEFHAQTAVEAAVKAYRILAKQGKTFKDIKSIR-IRTQEAAMRIIDKSGPLYNYADRDHCIQYMIAVPLITGNLTATDYSDEVARNPEIDNLRSKMYCIEDTHLTQNYHDPDKRSIGNALLIELNDGTQLDEIFVEYPVGHKFRREEGIPLLMNKFQR--------HLREHFVESPDKVDLIMKVSSKTNFLNMQIDKYMDLFTEG-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .:.: : *: *: .:* :**:** *: . : : ... .. : * .**. *. :: :*::* * .* *** *.:*.. *:. .* ::*: : ::.: :: : :.: * *: :.:*...:*:* *. : **: * . : * : . *. *:*. .:: : *. . *. : :* : : . :. ::::: : ***.: : ..:** . : :. . *. * : . : :: . * :: * *.:*: .. *: * :.. .: ... : :* *: . .:. : : : .:* : : ::*: . * :**: . * :: .::: . : :: . ", "identical_positions": 61, "similar_positions": 158, "identity": "11.23%" }, { "cls_id": "homologset.agr.HGNC:33905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10987-1", "uniprot_id": "ACT1_DROME", "id": "P10987-1", "name": "Actin-5C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDEEVAALVVDNGSGMCKAGFAGDDAPR---------------------------------------------------------------------------------------------------------AVFPSIVGRPRHQGVMVG-MGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYN-----------------ELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN------------------------TPAMYVAIQAVLS--------LYASGRTTGIVLDSGD-------------------GVSHTVPIYEGYALP--------------------------------------------------------HAILR------------------------------------------------------------------------------------------------------LDLAG-RDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACG---IHETTYNSIMKCDVDIRKD----------LYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGS----------------------------------------------------------------------------------------------------------------------ILASLST----------FQQMWISKQEYDESGPSIVHRKCF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02572-1", "uniprot_id": "ACT2_DROME", "id": "P02572-1", "name": "Actin-42A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDEEVAALVVDNGSGMCKAGFAGDDAPR---------------------------------------------------------------------------------------------------------AVFPSIVGRPRHQGVMVG-MGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYN-----------------ELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN------------------------TPAMYVAIQAVLS--------LYASGRTTGIVLDSGD-------------------GVSHTVPIYEGYALP--------------------------------------------------------HAILR------------------------------------------------------------------------------------------------------LDLAG-RDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMEACG---IHETTYNSIMKCDVDIRKD----------LYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVAPPERKYSVWIGGS----------------------------------------------------------------------------------------------------------------------ILASLST----------FQQMWISKQEYDESGPSIVHRKCF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A5A3E0-1", "uniprot_id": "POTEF_HUMAN", "id": "A5A3E0-1", "name": "POTE ankyrin domain family member F", "aln": "-----------------------------------------------------------------------------------------------------------------------MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCCRESGKSNVGTSG------------------------------DHDDSAMKTLRSKMGKWCRHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSSKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANGNSEVVKLLLDR-----------RCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLK-----------------------------------------------LTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPR---------------------------------------------------------------------------------------------------------AVFPSIVGRPRQQGMMGG-MHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYN-----------------ELRVAPEEHPVLLTEATLNPKANREKMTQIMFETFN------------------------TPAMYVAIQAVLS--------LYTSGRTTGIVMDSGD-------------------GVTHTVPIYEGNALP--------------------------------------------------------HATLR------------------------------------------------------------------------------------------------------LDLAG-RELPDYLMKILTEHGYRFTTMAEREIVRDIKEKLCYVALDFEQEMATVASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCG---IHETTFNSIMKSDVDIRKD----------LYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGS----------------------------------------------------------------------------------------------------------------------ILASLST----------FQQMWISKQEYDESGPSIVHRKCL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K3A7-1", "uniprot_id": "A0A0G2K3A7_RAT", "id": "A0A0G2K3A7-1", "name": "Unconventional myosin-VIIb", "aln": "MSVFRLGDHVWLDPPSSNKTGVAIGGIVKETKLGKTLIEDDEGKEHWISAEDLSTLRPMHPNSAQGVDDMIRLGDLNEAGVVHNLLIRYQQHKIYTYTGSILVAVNPFQMLPLYTLEQVQIYYSRHMGELPPHVFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATVSGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIHFNSSGVIEGASIEHFLLEKSRVCRQAAEERNYHIFYCMLMGMSLEEKNMLGLGMPSEYHYLTMGNCTSYEGLSDAKDYAHVRSAMKILQFSDSENWDISKLLAAILHLGNVGFMAAVFENLDSSDVMETPAFPFAMKLLEVQHQALRDCLIKHTIPILGEFVSRPLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPQAQDPQNVRRAIGLLDIFGFENFQNNSFEQLCINFANEHLQQFFVKHVFTMEQEEYLSENITWNYIHYTDNQPILDMLALKPMSIISLLDEESRFPQGTDVTMLQKLNSIHANNKSFLRPKSIHDTRFGIAHFAGDVYYQAEGFLEKNRDVLSTDILILIHSSKNKFLKEIFNLDLPQTKLGHGTICQVKTKTGGQIFKPSDSTKRSVTLSSQFKQSLEQLMKILTNCQPYFVRCIKPNEYKKPLLFDRELCIQQLRYSGMMETVHIRKSGFPIRYTFDEFSQRFRVLLPSPERVQFQNKHRQMTSRIADLCLGTDKEWKMGKTKIFLKDHQDTMLEIQRSQALDGAAIRIQRVLRGHKYRKEFLRQKRAAVTLQAVWRGHNQRKNFKLILMGFERLQAIARSHLLMRQFQTMRQKIVQLQARCRGYLVRQQVQAKRRAVVIIQAHARGMVARKSYWQQKSSGPPVILAKEPKGQGVALDRKRKSIYDTVTDTAMVEKVFGFLPAMIGGQEGPAPTRFEDLEVKTQKLHEVDLDTVPMTEMPGEDVDGLAEYTFPKFAVTYFQKSASHTHIQKPLRYPLLYHENDTDHSAALAVWIIILRFMGDLPEPQAYGRSSLTGSSVMRQIHDRLDKDSVTQGPQHNRSTQVASQQNIGEEVFKFDGPISDRPMSNLEKVHFIVGYAIMRPGLRDEIYCQICKQLSENYKTSSRARGWILLSLCLGCFPPSERFMKYLLNFISQGPASYGPFCAERLQRTFANGVRAEPPTWLELQAVKSKKHIPIQVILATGRSLTISVDSASTSREICQQIAQKQGLRDKLGFSLQVAVYDKFWSLGNSCDHVMDAVAQCEQLAWERGESQRQAPWRIYFRKEFFTPWHDSREDPVSTELIYHQVLRGVWSGEYNFEKEEDLVELLARHCYVQLGATVKSNAVQELLPSCVPSKLYRTKSPEKWASLVIAAHAKAPYTQSKATPLEVKEQTVEAARLLWPLLFSRLFEVTTLSGPRLPKTQLILAINWKGMYFLDQKERTLLGLSFAEVMGLIANRDAPGGKSLLLSTLHEEYEFASPSSVAIAEMVALFLAGLKERSVFAMALQDRKATDDVTLLPFKKGDLLILTKKQGLLASENWVLGQNDRTGKTGLVPTACLYTIPSVTKPSAQLLNLLAMSPEKRKLAAQEVQASEPPLEEQLTELPYTLEEFSYQYFRAPEKETISRAAMPMARSRGHLWAYSPEPLRQPLLKSVHDKAKLRDSACQIFLAILKYTGDYPSRQSWHSLELTDQMFSLALKEPALQDELYCQILKQLTHNSIRFSEERAWQLLWLCTGLFPPGKALLPHAQKFIDSRKKKPLALDCSRRLHRILRVGPRKQPPHHVEVKAAEQNVSKLHHEVYLPNDTNKTLEVSSSSRVRDLCEGIATRLQLASWDGCSLFIKITDKVISLKEGDFFFDSLRQVSDWVKKNRPQKEGASTTLPYQVFFMRKLWLNVTPGKDVNADTILHYHQELPKYMRGFHKCSREDAIYLAGLIYKIQFGSDRSQMASVSKILKELVPQNLTRLMSSEEWKKSLLLECDKHKNKSVAEAKVEFLKRIYRWPTFGSAFFEVKQTSEPSYPDILLIAINRHGLLLIHPKTKELLDTFPFTKISSWSSGNTYFHMALGSLGQGSRLLCETSLGYKMDDLLTSYVQQILSAVNKHRGFRANP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . :::: *: * :.*::.* :*: .* .* ::.: * ::.: *..: : . ::.:. *:.. ::* :.:. * ::: . : :.:.. : :* . *. . *:: : ::: :. *. :: :*** * : ::**: * :**.. *.: *.:*: * ** *:* * *: :. :* * ** :: :: : : : .. *:*.:.**:.. . ::*.: .* : ..:.* . .:.* .: * *: * .. : :. :* * : * . .:: :.. ::: ::* :** :. : ** .*: :* :*:.. : . . : * : : ", "identical_positions": 63, "similar_positions": 157, "identity": "2.98%" }, { "cls_id": "homologset.agr.HGNC:33906", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTQ2-1", "uniprot_id": "A0A0G2JTQ2_RAT", "id": "A0A0G2JTQ2-1", "name": "", "aln": "MTLHVGFLLVSICLFHSLFSFQEE-EYYAATIESIIRNPETEDGVCVFPFWYRSEIFYDCVTFNVKHKWCSLNKTFQGYWKYCALSDYAPCAFPFWYRRMIYWDCTKDGDMFGKKWCSLTPNFNKDHVWKYCI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UW26-1", "uniprot_id": "BSPH1_MOUSE", "id": "Q3UW26-1", "name": "Binder of sperm protein homolog 1", "aln": "MAQPLDFLLVSICLFHSLFSFQVE-DYYAPTIESLIRNPETEDGACVFPFLYRSEIFYDCVNFNLKHKWCSLNKTYQGYWKYCALSDYAPCAFPFWYRHMIYWDCTEDGEVFGKKWCSLTPNYNKDQVWKYCIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q075Z2-1", "uniprot_id": "BSPH1_HUMAN", "id": "Q075Z2-1", "name": "Binder of sperm protein homolog 1", "aln": "MG-SLMLLFVETTRNSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTKNFNKDRIWKYCE-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :*:*. * * : :.*:*:: : **. ** ***** *:. :***:. : :*********::****:*: .*:* *.******::***:**.**: ********* *:***::**** ", "identical_positions": 67, "similar_positions": 34, "identity": "50.0%" }, { "cls_id": "homologset.agr.HGNC:33908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNP0-1", "uniprot_id": "A0ABZ3NNP0_RAT", "id": "A0ABZ3NNP0-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "MELPTDPPLYTLNQSEKYRKCSNIFPRVTIDGFSLVPPLFYLSLSERRLELPLAPSSSSSGPASVPCSQCGRACGRHGFPSPVNPTFLISVPGSLCLLAICGARAPWRMGPPLDVWDFSS-PLLSLWMNRFYIYMGCALGVTLWFCVQIIIKKQVTRSQEKSVPGA---PDSSLSPQEKHTHVSGVKIFYGSQTGTAKGFAVVLAKAVTSLDLPVAIINLKEYDPDDNLIGEITSKN------------------VCAFLVATYTDGRPTESAEWFCKWLEEAANDFRFGKTYLKGLRYAVFG--LGDSAYRSHFN--KVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHGSIEADFTAWKTKFISRLQALQRGE-KKGCGGDCKRGKCESAQHGP--GEVRSHPHGELHPGDAEEEEPCESSSEDEHGTKGYQSLNSVVDVEDLGNIMNPVKREKREKAQPEEKVV-VHRNSEKNE--DSEARAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHRNMIKQFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISTFLVTNAQFPEEIRNLTPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLQALSAKQ--QRTVYRLTLVKCWNVDELQAYAELVSLGSPDFIEVKGVTYCGES--AASSLTMANVPWHEEVVRFVRELVDLLP----DYEIACEHEHSNCLLIGHKKFKIGGEWWTWIDYSRFQELVLQYEESGGSKTFSSKDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJM7-1", "uniprot_id": "TYW1_MOUSE", "id": "Q8BJM7-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "------------------------------------------------------------------------------------------------------------MG-PLDVWDLS--PLLSLWMNRFYIYMGCALGLTLCICVQ-IIKKQVTRSQEKRVPGA---PDSSLSPQKKQTHVSGVKIFYGSQTGTAKGFAVVLAKAVTSLDLPVAIINLKEYDPDDSLIGEITSKT------------------VCAFLVATYTDGCPTESAEWFCKWLEESANDFRFGKTYLKGLRYAVFG--LGDSAYRSHFN--KVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHGSIEADFTAWKTKFISRLQALQRGE-KKACGGNCKRGKCESAQHGP--GEARPHPQGELHPGDAEEEEPCESSSEDELGTQDYQSLTSVVDVEDLGNIMNPVKREKREKSHQDGKAA-MQRNPEKTE--DGEGRAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHQNMIKQFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISSFLVTNAQFPEEIRKLTPVTQLYVSVDASTRDGLKKIDRPLFKDFWQRFLDSLKALSAKQ--QRTVYRLTLVKCWNVDELQAYAELVSLGNPDFIEVKGVTYCGES--AASSLTMANVPWHEEVVRFVRELVDLLP----DYEVACEHEHSNCLLIGHKKFKIDGEWWTWINYSRFQELVLQYEESGGSKTFSSRDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUM6-1", "uniprot_id": "TYW1B_HUMAN", "id": "Q6NUM6-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B", "aln": "------------------------------------------------------------------------------------------------------------MDPSADTWDLSS-PLISLWINRFYIYLGFAVSISLWICVQIVIEMQ--------------------------------------------GFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKN------------------VCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRDAVFG--LGNSAYASHFN--KVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSG-LFRNMGRNE--DGERRAMITP--ALREALTKQ-----------------VDAPRERSLLQTHILWN-ESHRCMETTPSLACANKCVFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQ--QRTVYRLMLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCRES--SASSLTMAHVPWHEEVVQFVRELVDLIP----EYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKNKSKAISGC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08C92-1", "uniprot_id": "TYW1_DANRE", "id": "Q08C92-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "-----------------------------------------------------------------------------------------------------------MSGVLNDVRDYTEGYLQVLWQNRLYVYSTAAVLIGVWFTVNMLFKKKKMVHPVSPLASKSVKKQEPASEAKKVIYVSGVKVFYGSQTGTAKGFAKELAEDVIAQGIQCEVIDMKDFDPEDRLAEECTSKI------------------ICVFLVATYTDGQPTESAEWFCKWLEEASTDFRYGKTYLKGMRYAVFG--LGNSVYVGHFN--TVSKSIDKWLWMLSAARIMTRGEGDCNVVKSRHGSVQADFQVWKGKFLNRLQALAKGE-KKACSGNCKKASCKNKKKHK----EEAEDNHSLAEKNNSEEELMESSSDEESSSEDEKSHGSVIDMEDLGNVMNHMKKAKQRMEEDEEDSQRVKQNGERKSECEEERREMITP--ALRDSLTKQGYKLIGSHSGVKLRRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDPAEKIIQEAMENHRNMIRQFRGVPGVRPERFEEGLTVKHCALSLVGEPIMYPEINSFLKLLHQQNISSFLVTNAQFPEEIRSLVPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLRALGEKQ--QRTVYRLTLVKAWNVDELKAYADLIALGQPDFIEVKGVTYCGES--SASSLTMANVPWHEEVIYFVQQLANLLP----DYEIACEHEHSNCLLLANHKFKVDGEWWTWIDYERFQELIQQYEESGGTKNFSAMDYMAKTPSWAVFGAGERGFDPTDTRFQRKNKTKDISGC---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08960-1", "uniprot_id": "TYW1_YEAST", "id": "Q08960-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase", "aln": "----------------------------------------------------------MDGFRVAGALVVGALTAAYLYFGGRFSIALVIIVG----YGIYCNEASGGSQDSQEKLDLNKQQKKPCCSDKKIADGGKKTGGCCSDKKNGGGKGGGCCSSKGGKKGG-----CCSSKGGKKGGCCSSKKNIGDNENTATEVEKAVNYPVTVDFTEVFRKPTKKRSSTPKVFSKNSSSNSRVGKKLSVSKKIGPDGLIKSALTISNETLLSSQIYVLYSSLQGAASKAAKSVYDKLKELDELTNEPKLLNLDDLSDFDDYFINVPVENALYVLVLPSYDIDCPLDYFLQTLEENANDFRVDSFPLRKLVGYTVLGLGDSESWPEKFCYQAKRADHWISR-LGGRRIFPLGKVCMKTGGSAKIDEWTSLLAETLKDDEPIIYEYDENADSEEDEEEGNGSDELGDVEDIGG-KGSNGKFSG--ADEIKQMVAKDSPTYKNLTKQGYKVIGSHSGVKICRWTKNELRGKGSCYKKSLFNIASSRCMELTPSLACSSKCVFCWRHGTNPVSKNWRWEVDEPEYILENALKGHYSMIKQMRGVPGVIAERFAKAFEVRHCALSLVGEPILYPHINKFIQLLHQKGITSFLVCNAQHPEALRNIVKVTQLYVSIDAPTKTELKKVDRPLYKDFWERMVECLEILKTVQNHQRTVFRLTLVKGFNMGDVSAYADLVQRGLPGFIEVKGATFSGSSDGNGNPLTMQNIPFYEECVKFVKAFTTELQRRGLHYDLAAEHAHSNCLLIADTKFKINGEWHTHIDFDKFFVLLN----SG--KDFTYMDYLEKTPEWALFGNG--GFAPGNTRVYRKDKKKQNKENQETTTRETPLPPIPA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :: : : . : * *. .. : : :*. : *. : .:: :.. :: : ** : . * : ..*: :. ::: *::* * ...: : . : : : .* *: :. * :.. . .: . : * :* :. :. * : .: : . . . . : * . * : *:: . . **** . * :. .: ::. * **** ******:.****** * .***..:* *::* .* *:::*::.* .**:*::****: .*** :.: *:***********:**.** :::**** *::*** ***.* :*.: *******:**.*: ***:****:****:::::.*. * * ****:** *** :*:.::.***:*: * *.******.*:. .* ...*** ::*::** : **: :. : .*::*.** ******:.. ***:.*** * *::.:* *: ** * *: **: :** **:** .* * :** **:*.* . ", "identical_positions": 189, "similar_positions": 186, "identity": "21.26%" }, { "cls_id": "homologset.agr.HGNC:3391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29322-1", "uniprot_id": "EPHA8_HUMAN", "id": "P29322-1", "name": "Ephrin type-A receptor 8", "aln": "-------------------------------MAPARGRLPPALWVVTAAAAAAT---CVS-------------------AARGEVNLLDTSTIHGDWGWLTYPAHGWDSIN-EVDESFQPIHT------YQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGAST--QESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEE--RRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNL-ISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRA--------------------------------AVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYY-EKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPR--PRYDTRTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQ-----------NGQAPPPVFLPLHH--PPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPG--QRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O09127-1", "uniprot_id": "EPHA8_MOUSE", "id": "O09127-1", "name": "Ephrin type-A receptor 8", "aln": "-------------------------------MAPARARLSPALWVVT-AAAAAT---CVS-------------------AGRGEVNLLDTSTIHGDWGWLTYPAHGWDSIN-EVDESFRPIHT------YQVCNVMSPNQNNWLRTNWVPRDGARRVYAEIKFTLRDCNSIPGVLGTCKETFNLHYLESDRDLGAST--QESQFLKIDTIAADESFTGADLGVRRLKLNTEVRGVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEE--RRDACMACELGFYKSAPGDQLCARCPPHSHSATPAAQTCRCDLSYYRAALDPPSAACTRPPSAPVNL-ISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSHCEACGSGTRFVPQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSNLSPEPRSA--------------------------------AVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYY-EKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPR--PRYDTRTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQ-----------NGQAPPPVFLPLNH--PPGKFPETQFSAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGESGEVCYGRLQVPG--QRDVPVAIKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLDALVHSPESLRATATVSRCPPPAFARSCFDLRAGGSGNGDLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLSSTQGPRRHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29321-1", "uniprot_id": "EPHA8_RAT", "id": "P29321-1", "name": "Ephrin type-A receptor 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIHIEKIIGSGESGEVCYGRLQVPG--QRDVPVAIKALKAGYTERQRQDFLREAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRATATVSRCPAPAFARSCFDLRAGGNGNGDLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLHMNAQDVRALGITLMGHQKKILGSIQTMRSQLSCTQGPRRHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDT-TREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQNSDVD---INTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKS-PEVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTG-VLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTR------PSPESDGNHILDGQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** ***.*: *:** ***::* :*: ****:**.* :*: * *** **:*********:* *:*****.. .**:**********:***.:**:* :**: **:*:.:** ****:.*:********:**:..*:**::****** :*: .. **** *****:***********.*:*******:***:***::******** :*:***.*:*:********.**.**:*******:*:*::** *: :**.*: * :.*:** :* ... . . * . . . ::.. **: *:*.** .** .. . : ::.**:: :****:******* . : : : : ", "identical_positions": 197, "similar_positions": 101, "identity": "17.59%" }, { "cls_id": "homologset.agr.HGNC:33910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UH36-1", "uniprot_id": "SRR1L_HUMAN", "id": "Q9UH36-1", "name": "SRR1-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAAAALESWQAAAPRKR-RSAARRPRRREAAPRGREAAPRGREAAPRGPEAEFESDS-GVVLRRIWEAEKDLFISDFWSSALETINRCLTKHLEQLKAPV----GTLSDIFGNLHLDS-LPEESDVATDSIPREILVTGTCHLKCVCYGIGNFATCIVARNQLTFLLLLLEKCQIPRS---HCWVYDPLFSQLEIEVLNTLGVTVLSENEEGKR-----SIRGEPTIFYMLHCG---TALYNNLLWSNWSVDALSKMVIIGNSFKGLEERLLARILQKNYPYIAKILKG------LEELEFPQTSQYMD-IFN-DTSVHWFPVQKLEQLSI-------------------DIWEFREEPDYQDCEDLEIIRNKREDPSATD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2M3-1", "uniprot_id": "SRR1L_MOUSE", "id": "Q8K2M3-1", "name": "SRR1-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAALEPWSAVAPRRRKRAAGRRPRPGE------------------GPRAEPEADG-EAVLRRLREAEEDLRISDFCSSALETITECLRKQLEQLQP--------LTEALGRLHLGSSLPSAS--------QEPLASSASHVKCVCYGLGTFASCPTARIQLAFMLLFLEKCQVPRS---HCWVYDPLFSQTEVSVLTSLGVTVLSENEEGKR-----SVQGQPTVFYMPHCG---TALYNNLLWSNWSADALSRVLIIGNSFRGLEERLLARILQENYPYIAKVSDR------IAGPGF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BJQ4-1", "uniprot_id": "A0A8M2BJQ4_DANRE", "id": "A0A8M2BJQ4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MACNEGWQVAGRRKG---AARRGKQVLN----------------PKLDSQQDSDC-KIDQQKIIHGMNELRGETFWMEWKDLLCERLLSSTSEQSE----------------------------------------DASLLQCVCYGLGHFESCVSARFQLAMLLLLLETLQIPVS---SCCVYDPVFSPSECDALKELGFTVLTENEEGKR-----AVY-QPTLFYLMHCG---KALYNNLLWRNWTPRTLQKMTIIGNSFNGIQERMLQRELERDYSFLSRVSLPSNMIGVCEETPLSCSSRFLD-VFN-DTALIQFPLENLNKLPE-------------------CTWTEPSEPLYQHCQDLEIIQREKD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEB5-1", "uniprot_id": "SRR1L_DROME", "id": "Q9VEB5-1", "name": "SRR1-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNSGEDFQVVTRKKWMARKCLRRRDRHK------------------SESDYLIDCPDVNVEKFQPRLENLCTEMCQSDYFLVAMEALQQQLEGIRK------------------------------------------PLERIVCLGLGPFSRTYHALHQAAFVIGLHRHHKIR-----EALYFDPVFRDSEKELIRLFDGCIMSKDCAGKH-----EAT-VPTLYYLPHCP---YALMHNILWSNWKRETLPNVFLISNSFE-----MLTMTPRNQDDHITRIVEH------CTETPLEDDYEHHN-VFN-DLSLHTFPQESLPGSND-------------------EAFWTRCAPLKVNEDELITETETSLAALKLESE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06688-1", "uniprot_id": "SRR1L_YEAST", "id": "Q06688-1", "name": "SRR1-like protein BER1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFKASGTKFKKTGKKVVP------------------------------------AKAFEEIVQTNRDVLKKSAFLSDLLENLQPHLNNIKK----------------------------------------------IRCVAIGNFKEDFPATYQFALLLEITDYIKSEDERDVVVSLYDPIFTKEEIQYLKSLGSKWLIEEEFSEND----AIDYESVLYFLPHAP---LDLTENILSS------QRPHLWLANNMISHTDRYTKAKLCENYPNLSKLVHYLQTNAPPEVKKAHDVDGFAT-FIPKRKRKNRNNSSKLKVTPS-------------------DIDYDSIAPKFKSCQILTDFDEGKYLKEKPWINSFSDLTLHAIEY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5U2Y6-1", "uniprot_id": "TFP11_RAT", "id": "Q5U2Y6-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGHLDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDEERPSFGGKRARDYSAPVNFISAGLKKGAAEEADSEDSDAEEKPVKQEDFPKDLGPKKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQSLQDFPVADSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKG---RVSKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHSVPDEGVPLLAQLPPTAGKEAKVPGFALPELEHNLQLLIERTEQEIIQSDRQLQYERDMVVSLSHELEKTAEVLAHEERVISNLSKVLALVEECEHRMQPHGADPLTLDECARIFETLQDKYYEEYRLADRADLAVAIVYPLVKDYFKDWHPLEDSNYGTQIISKWKSLLENDQLLSHSSQDLSSDAFHRLMWEVWMPFVRNVVAQWQPRNCEPMVDFLDSWAHIIPVWILDNILDQLIFPKLQKEVDNWNPLTDTVPIHSWIHPWLPLMQARLEPLYSPVRSKLSSALQKWHPSDASAKLILQPWKEVLTPGSWEAFMLRNIVPKLGMCLGELVINPHQQHMDAFYWVMDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : : . : : : **: : : : ... . :: . . : .. : .: ", "identical_positions": 2, "similar_positions": 27, "identity": "0.24%" }, { "cls_id": "homologset.agr.HGNC:33911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3C0-1", "uniprot_id": "RNK_MOUSE", "id": "Q8K3C0-1", "name": "Ribonuclease kappa", "aln": "---------------------------------------MASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHS-----AVLIEDVPFTEKDFENG---PQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVR---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P5S7-1", "uniprot_id": "RNK_HUMAN", "id": "Q6P5S7-1", "name": "Ribonuclease kappa", "aln": "MGWLRPGPRPLCPPARASWAFSHRFPSPLAPRRSPTPFFMASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHS-----AVLIEDVPFTEKDFENG---PQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVR---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P442-1", "uniprot_id": "RNKB_DANRE", "id": "Q0P442-1", "name": "Ribonuclease kappa-B", "aln": "---------------------------------------MPSLLFCGPKLAACGIVLSVWGVIMLSMLGIFFSAKS-----AVLIEDVPFTEEDIRNDKDPPQIIYGLYNQVGINCFIAAAIYVGVGAVSLCQVRLNKRQEYMVT---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0P467-1", "uniprot_id": "RNKA_DANRE", "id": "Q0P467-1", "name": "Ribonuclease kappa-A", "aln": "---------------------------------------MVSLLFCGPKLAACGLVLSIWGVIMLALLGIFFTTHS-----AILIEDVPLTEEDLHSQDTPPQSVYKLYNQVGYNCFIAAVIYVGIGFLSFCQVRLNKRKEYLVH---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MSF5-1", "uniprot_id": "RNK_DROME", "id": "Q8MSF5-1", "name": "Ribonuclease kappa", "aln": "------------------------------------------MKICGPKLSLCGLIISVWGIVQLVLMGLFFYINS-----VALIEDLPL-EEEYHSLEDFYAAANRAYNQNAYNCWIAACIYVLTLLLSAQQFYMNSRVTAN-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W286-1", "uniprot_id": "Q9W286_DROME", "id": "Q9W286-1", "name": "", "aln": "-------------------------------------------MFCGRKCCLFCLFMSAWGFLMLNLLGIFFYVQS-----LMLLESLPL-PHHFPSQEAFKEQADEAYQDVSTRCFVAAVFYLGFVFIAIVAIRRDNKRRKRLYKRGPGHLRFRR----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C5R9-1", "uniprot_id": "RNK_YEAST", "id": "P0C5R9-1", "name": "V-type proton ATPase subunit f", "aln": "---------------------------------------MRPVVSTG--KAWCCTVLSAFGVVILSVIAHLFNTNH-----ESFVGSIND-----------PEDG----PAVAHTVYLAALVYLVFFVFCGFQVYLARRKPSIELR--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I5ZM61-1", "uniprot_id": "A0A8I5ZM61_RAT", "id": "A0A8I5ZM61-1", "name": "BPTF-associated chromatin complex component 1", "aln": "--------------------------------------MTSASTKVGEIFSAAGAAFTKLGELTMQLHPVSDSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKTTVKRKVYEDSGIPLPAESPKKGPKKMTSGVLSPPNAPPPSSSSVPEAGGPPIKKQKADVTLSALNDSDANSDLVDVEGLGETPPAKKLNFDQGRSPPPPTLAGVGKVLTWMVGDGPSRSPFLVQGPQKEDSAQGTGPVSNTTIEEVRVFLEKNPPCLLHLCPLYFLFQTA", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: * : : : : : : .* ", "identical_positions": 3, "similar_positions": 10, "identity": "1.05%" }, { "cls_id": "homologset.agr.HGNC:33914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C4X7-1", "uniprot_id": "MNARL_MOUSE", "id": "Q8C4X7-1", "name": "Major intrinsically disordered NOTCH2-binding receptor 1-like homolog", "aln": "MKGDMDLSVLPNNNHPDKFLQLDVKSLMRSSTLLQASLARFPGGNYPATQHWQNLVYSQREK-TIATQRIKGFGVENPVLPESPPASMSSVMKNNPLYGDITLEEAMEERKKSPSWTIEEYDKHSVHTNLSGHLKENPNDLRFWLGDTYTPGFDTLLKKKKKRNKRSKLCHMGLILLLVASILVTIVTLSTIFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LWI8-1", "uniprot_id": "A0ABK0LWI8_RAT", "id": "A0ABK0LWI8-1", "name": "", "aln": "MKGDMDLSVLPNNNHPDKFLQLDVKSLMRSSTLLQASLARFPGGNYPATQHWQNLVYSQGEK-NIATQRIKGFGGENPVLPESPPASMSSVMKNNPLYGDVSLEEAMEERKKNPSWTIEEYNKHSVHSNLSGHLKENPNDLRFWLGDMYTPGFDTLLKKKKKRNKRSKLCHMGLILLVVSSILVTVVTLSALFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59773-1", "uniprot_id": "MNARL_HUMAN", "id": "P59773-1", "name": "Major intrinsically disordered NOTCH2-binding receptor 1-like", "aln": "----MDLSVLPNNNHPDKFLQLDVKSLTRSSALLQASLVRFPGGNYPAAQHWQNLVYSQREKKNIAAQRIRGSSADSLVTADSPPPSMSSVMKNNPLYGDLSLEEAMEERKKNPSWTIEEYDKHSLHTNLSGHLKENPNDLRFWLGDMYTPGFDTLLKKEEKQEKHSKFCRMGLILLVVISILVTIVTIITFFT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********************** ***:******.*********:********** ** .**:***:* . :. * .:***.**************::**********.********:***:*:******************* ***********::*::*:**:*:******:* *****:**: ::*:", "identical_positions": 149, "similar_positions": 31, "identity": "76.8%" }, { "cls_id": "homologset.agr.HGNC:33915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIM6-1", "uniprot_id": "STRC_MOUSE", "id": "Q8VIM6-1", "name": "Stereocilin", "aln": "MALSLQPQLLLLLSLLPQ--EVTSAPTGPQSLDAGLSLLKSFVATLDQAPQRSLSQSRFSAFLANISSSFQLGRMGEGPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGDVLALLGQEQTPRDFLVHQAGVLGGLVEALLGALVPGGPPAPTRPPCTRDGPSDCVLAADWLPSLMLLLEGTRWQALVQLQPSVDPTNATGLDGREPAPHFLQGLLGLLTPAGELGSEEALWGGLLRTVGAPLYAAFQEGLLRVTHSLQDEVFSIMGQPEPDASGQCQGGNLQQLLLWGMRNNLSWDARALGFLSGSPPPPPALLHCLSRGVPLPRASQPAAHISPRQRRAISVEALCENHSGPEPPYSISNFSIYLLCQHIKPATPRPPPTTPRPPPTTPQPPPTTTQPIPDTTQPPPVTPRPPPTTPQPPPSTAVICQTAVWYAVSWAPGARGWLQACHDQFPDQFLDMICGNLSFSALSGPSRPLVKQLCAGLLPPPTSCPPGLIPVPLTPEIFWGCFLENETLWAERLCVEDSLQAVPPRNQAWVQHVCRGPTLDATDFPPCRVGPCGERCPDGGSFLLMVCANDTLYEALVPFWAWLAGQCRISRGGNDTCFLEGMLGPLLPSLPPLGPSPLCLAPGPFLLGMLSQLPRCQSSVPALAHPTRLHYLLRLLTFLLGPGTGGAETQGMLGQALLLSSLPDNCSFWDAFRPEGRRSVLRTVGEYLQREE--PTPPGLDSSLSLGSGMSKMELLSCFSPVLWDLLQREKSVWALRTLVKAYLRMPPEDLQQLVLSAEMEAAQGFLTLMLR--SWAKLKVQPSEEQAMGRLTALLLQRYPRLTSQLFIDMSPLIPFLAVPDLMRFPPSLLANDSVLAAIRDHSSGMKPEQKEALAKRLLAPELFGEVPDWPQELLWAALPLLPHLPLESFLQLSPHQIQALEDSWPVADLGPGHARHVLRSLVNQSMEDGEEQVLRLGSLACFLSPEELQSLVPLSDPMGPVEQGLLECAANGTLSPEGRVAYELLGVLRSSGGTVLSPRELRVWAPLFPQLGLRFLQELSETQLRAMLPALQGASVTPAQAVLLFGRLLPKHDLSLEELCSLHPLLPGLSPQTLQAIPKRVLVGACSCLGPELSRLSACQIAALLQTFRVKDGVKNMGAAGAGSAVCIPGQ---PTTWPDCLLPLLPLKLLQLDAAALLANRRLYRQLPWSEQQAQFLWKKMQVPTNLSLRNLQALGNLAGGMTCEFLQQISSMVDFLDVVHMLYQLPTGVRESLRACIWTELQRRMTMPEPELTTLGPELSELDTKLLLDLPIQLMDRLSNDSIMLVVEMVQGAPEQLLALTPLHQTALAERALKNLAPKETPISKEVLETLGPLVGFLGIESTRRIPLPILLSHLSQLQGFCLGETFATELGWLLLQEPVLGKPELWSQDEIEQAGRLVFTLSAEAISSIPREALGPETLERLLGKHQSWEQSRVGHLCGESQLAHKKAALVAGIVHPAAEGLQEPVPNCADIRGTFPAAWSATQISEMELSDFEDCLSLFAGDPGLGPEELRAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGERELQELTLVDWGVLSSLGQIDGWSSMQLRAVVSSFLRQSGRHVSHLDFIYLTALGYTVCGLRPEELQHISSWEFSQAALFLGSLHLPCSEEQLEVLAYLLVLPGGFGPVSNWGPEIFTEIGTIAAGIPDLALSALLRGQIQGLTPLAISVIPAPKFAVVFNPIQLSSLTRGQAVAVTPEQLAYLSPEQRRAVAWAQHEGKEIPEQLGRNSAWGLYDWFQASWALALPVSIFGHLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUE8-1", "uniprot_id": "D3ZUE8_RAT", "id": "D3ZUE8-1", "name": "", "aln": "MALSLQPLLLLLLSIPPQ--EVTLAHVGLQSLDVGLSLLKSFISTLDHTPQRYLSQSRFSAFLANISSSFEFGRMGEGPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGDVLALLGQEQTPRDFLVHQAGVLGGLVEALLGALVPGGPPAPTRPPCTRDGPSDCVLAADWLPSLMLLLEGTRWQALVQLQPSVDPTNATDLDGREPVPHFLQGLLGLLTPAGELGSEEALWGGLLRTVGAPLYAAFQEGLLRVTHSLQDEVFSIMGQPEPDASGQCQGGNLQQLLLWGMRNNISWDARALGFLSGSPPPPPALLHCLSRGVPLPRASQAAAHISPRQRRAISVEALCENHSGPEPPYSISNFSIYLLCQHIKPATPRPPPTTPQPPPTTPPPPPTTPQPPPTTPRPPPTTPQPPPTTPQPPPSTAVICQTAVWYAVSWAPGARGWLQACHDQFPDQFLDMICGNLSFSALSGPNRRLVKQLCAGLLPPPTSCPPGLVPVPLTPEIFWGCFLENETLWAERLCVEESLQAVPPRNQAWVQHVCRGPTLDATDFPPCHVGPCGERCPDGGSFLLMVCANDTLYEALVPFWAWLAGQCRISRGGNDTCFLEGMLGPLLPSLPPLGPSPLCLAPGPFLLGMLSQLPRCQSSVPALAHSTRLHYLLRLLTFLLGPGAGGAETQRMLGRALLLSSLPDNCSFWDAFRPEGRRSVLRTVGEYLQREE--PTPSGLESTDSLGSGLSKMELLSCFSPVLWDLLQREKSVWALRILVKAYLHMPPDALQQLVLTAETAAAQGFLTLMHR--SWAKLRVQPSEEQAMGRLTALLLQRHPHLTSQLFIDMSPLIPFLAVPDLMRFPPSLLANDSVLAAIRDHSSGMKPEQKEALAKRLLAPELFGEVPDWPQELLWAALPLLPYLPLESFLQLSPHQIQALEDIWPVAGLGPGHARHVLRSLVNQSIEDGEEQVRRLGSLACFLSPEELQSLVPLSDPMGPVEQGLLECAANGTLSPEGRVAYELLGVLRSSGGTVLSPRELRVWAPLFPQLGLRFLQELSEPQLRAMLPALQGASVTPAQAVLLFGRLLPRHDLSLEELCSLHPLLPGLSPQTLQAIPKRVLVGACSCLGPELSRLSACQIAALLQTFRVKDGVKNMGAAGAGTTVCIPGQ---PTTWPDCLLPLLPLKLLQLDTAALLANRRLYRQLPWSEQQAQFLWKKMQVPTNLTLRSLQALGNLAGGMSCEFLQQISSMVDFLDVVHMLYQLPIGVRESLRACIWAELQRRMAMPEPELTTLGPELSELDTKLLLDLPIQLMDRLSNDSVMLVVELVQGAPEQLLALTPLHQAALAERALKALAPKETPISQEVLETLGPLVGFLGIDSTRRIPLPILLSHLSQLQGFCLGETFATELGWLLLQEPVLGKPELWSRDEIEQAGRLVFTLSAEAISLIPREALGPETLERLLGKQQSWEQSRVGHLCGKSQLAHKKTALVAGIVHPAVEGLQDPVPNCADIRGTFPAAWSATQIAEMELSDFEDCLSLFAGDPGLGPEELQAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGERELQELTLVDWGVLSSLGQIDGWSSVQLRAVVSSFLRQSGRHVSHLDFIYLTALGYTLCGLRPEELQHISSWEFSQAALFLGSLHLPCSEAQLEALAYLLVLPGGFGPVSNWGPEIFTEIGTIAAGIPDLALSALLRGQIQGLTPLAISVIPAPKFAVVFNPIQLSSLTRGQAAAVTPEQMAYLSPEQRRAVAWAQHEGKEIPEQRGRSSAWGLCDWFHASWALTLTISFFGHLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NGW2-1", "uniprot_id": "STRCL_HUMAN", "id": "A6NGW2-1", "name": "Putative stereocilin-like protein", "aln": "MALSLWPLLLLLLLLLLLSFAVTLAPTGPHSLDPGLSFLKSLLSTLDQAPQGSLSRSRFFTFLANISSSFEPGRMGEGPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGDMLALLGQEQTPRDFLVHQAGVLGGLVEVLLGALVPGGPPTPTQPPCTRDGPSDCVLAADWLPSLLLLLEGTRWQALVQVQPSVDPTNATGLDGREAAPHFLQGLLGLLTPTGELGSKEALWGGLLRTVGAPLYAAFQEGLLRVTHSLQDEVFSILGQPEPDTNGQCQGGNLQQLLLWGVRHNLSWDVQALGFLSGSPPPPPALLHCLSTGVPLPRASQPSAHISPRQRRAITVEALCENHLGPAPPYSISNFSIHLLCQHTKPATP------------------------------------------QPHPSTTAICQTAVWYAVSWAPGAQGWLQACHDQFPDEFLDAICSNLSFSALSGSNRRLVKRLCAGLLPPPTSCPEGLPPVPLTPDIFWGCFLENETLWAERLCGEASLQAVPPSNQAWVQHVCQGPTPDVTASPPCHIGPCGERCPDGGSFLVMVCANDTMYEVLVPFWPWLAGQCRISRGGNDTCFLEGLLGPLLPSLPPLGPSPLCLTPGPFLLGMLSQLPRCQSSVPALAHPTRLHYLLRLLTFLLGPGAGGAEAQGMLGRALLLSSLPDNCSFWDAFRPEGRRSVLRTIGEYLEQDEEQPTPSGFEPTVNPSSGISKMELLACFSPVLWDLLQREKSVWALQILVQAYLHMPPENLQQLVLSAEREAAQGFLTLMLQGKLQGKLQVPPSEEQALGRLTALLLQRYPRLTSQLFIDLSPLIPFLAVSDLMRFPPSLLANDSVLAAIRDYSPGMRPEQKEALAKRLLAPELFGEVPAWPQELLWAVLPLLPHLPLENFLQLSPHQIQALEDSWPAAGLGPGHARHVLRSLVNQSVQDGEEQVRRLGPLACFLSPEELQSLVPLSDPTGPVERGLLECAANGTLSPEGRVAYELLGVLRSSGGAVLSPRELRVWAPLFSQLGLRFLQELSEPQLRAMLPVLQGTSVTPAQAVLLLGRLLPRHDLSLEELCSLHLLLPGLSPQTLQAIPRRVLVGACSCLAPELSRLSACQTAALLQTFRVKDGVKNMGTTGAGPAVCIPGQQPIPTTWPDCLLPLLPLKLLQLDSLALLANRRRYWELPWSEQQAQFLWKKMQVPTNLTLRNLQALGTLAGGMSCEFLQQINSMVDFLEVVHMIYQLPTRVRGSLRACIWAELQRRMAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTESTRQIPLQILLSHLS----FCLGETFATELGWLLLQESVLGKPELWSQDEVEQAGRLVFTLSTEAISLIPREALGPETLERLLEKQQSWEQSRVGQLCRGPQLAAKKAALVAGVVRPAAEDLPEPVPNCADVRGTFPAACSATQIAEMELSDFKDCLTLFAGDPGLGPEEPRAAMGKAKWLWGPPRGFGPEQILQLGRLLIGLGDQELQELILVDWGVLSTLGQIDGWSSTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLCGLRPEELQHISSWEFSQAALFLGTLHLQCSEEQLEFLAHLFVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLRGQIQGVTPLAISVIPPPKFAVVFSPIQLSSLASAQAVAVTPEQMAFLSPEQRRAVAWAQHEGKESPEQQGRSTAWGLQDWSRPSWSLVLTISFLGHLL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** * ***** : ** * .* :*** ***:***:::***::** **:*** :*********: *******************************************:**************************.***********:**:*********************:*************:**********.*****..*************:*****:*************************************:******:.***************:*:*:***.:******************** *********.:***********:******** ** **********:***** ***** ** ***:.****************:************:*** **.*********..* ***:************* ** ******:****************** * ******* *********:*** *.* ***::**************:*******:**.*****.********************:******************:************************.*****************:****:* ***:****************************:****:::* ***.*::.: . .**:******:*******************: **:***:***: ******:** ********* : .**:* ******:**********:*:********:*********.*********************:*.**:********************* ********.*****:****.************** **.*.*****************::****** ***.******************* ****:******************************:**************.************.*******.***:**********:*****:************ **************:**********.********** *****************::***.:****** ********************: ******* * :*********************:**.*****.*****:*******.******:****:**** ** *******:******:***** **:****. **:****************:*:*****:** *************:*******: *******:* ************** :***:*** ******* ******************.*********:**:***********:**** *************** *:*********:** .*** **:*****:*:**.*.* :*******:******* *****:*******:***:************ :******* ******** ***************::***** ********:********* *** ******************::*******:************************:*** *** *** **:*:********:*********************************:*********.*******.*******: .**.******:*:****************** *** **.:**** ** :.**:*.*.:*::****", "identical_positions": 1505, "similar_positions": 177, "identity": "82.78%" }, { "cls_id": "homologset.agr.HGNC:3392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09759-1", "uniprot_id": "EPHB1_RAT", "id": "P09759-1", "name": "Ephrin type-B receptor 1", "aln": "-------------------------------------------------------------MALDCLLLFLLAS---AVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNT-------IRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKAGYEPENS-VACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRN-VISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFP--------------------------------PQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEK-EHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKR-----------------AYSKEAVYS-------DKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPG--KREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBF3-1", "uniprot_id": "EPHB1_MOUSE", "id": "Q8CBF3-1", "name": "Ephrin type-B receptor 1", "aln": "-------------------------------------------------------------MALDCLLLFLLAS---AVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNT-------IRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENS-VACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRN-VISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFP--------------------------------PQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEK-EHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKR-----------------AYSKEAAYS-------DKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPG--KREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54762-1", "uniprot_id": "EPHB1_HUMAN", "id": "P54762-1", "name": "Ephrin type-B receptor 1", "aln": "-------------------------------------------------------------MALDYLLLLLLAS---AVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNT-------IRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENS-VACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVACTSVPSGPRN-VISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFP--------------------------------PQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEK-EHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKR-----------------AYSKEAVYS-------DKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPG--KREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQISQSPTAMA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFD--AATREPPPWQTDSYRLIARIAAGEGRFNQNSD---VDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYL-CKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKS-PEVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTR---GGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD-GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* :*::: * :* ::.:: * * * ** * . :..*: *: * *:* **:* * **** :.**:* .*:*:* *::**:**** :*. . ******.* :** * **::.. *. .* : ***.*. : : . :.:****:*:. :.::*.*:**:* ***:*:*:*:*:: .**::.:*** * ** ** * * : .***: *** :.* * *:***:* : * * **.****: : :*. ** ****: *. *: **.**.:. .**:*.* :*:** * .:.* * *:.* * .: :*::** *:.* .* :. . .. * . * :. . : .*. *. ** : * :.* :::::.* . *.**.:*:***.** . * . :..: :**:.. *** :: :: * :. *.* :* *.: : **:*:: * * : :*.* .:: ..*:* ** . * .***.:* *:*.:*. : *** . . : *: :***: .:**:*:* :: :: *.: *:.: . * .**: * . : *:**.******:*:****:***..::.** :**.****:* :****:* ::* *******.* *** * ***:************:* *:****:*.*******:****:**:*** ***:* .:**: ******:**.**::************:***::*:**::****** ::: :. * ***************:*************:*:*****:******: ******::**:.****.***** **:*********:*. ** **.**.***:: *:* ** *. . . .: :** . . . * :.* **. *** :* . * *.: . * ::::*:::* :*:**.******* . :.: . : ", "identical_positions": 434, "similar_positions": 297, "identity": "38.89%" }, { "cls_id": "homologset.agr.HGNC:33920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJB8-1", "uniprot_id": "A0A8I6GJB8_RAT", "id": "A0A8I6GJB8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------MNITVETTKPALLLDAGEITLGIQSRKEMEN-HYRVKENRNILTALCALINFGEGKVKVQSKNPDYSLAKHGVGDDLETSFKNIWPSTP--LVFKQDQLNVFICVQPQSPDGSGGKPATIAINLFMRNGASSVEMSFDVAQEFLEKMAGAGGRSPL-ARLKGKRPGDGLQEEVHVQELAAAFFKQSKLTKMEKFPFSESKNVEYKSFETKKLL--QRVKEILPRTVSAFANTDGGYLFIGLDEKEQQIVGFEAKNCHPKCLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAVCSYVCALRVERFCCAVFAAEPDSWHVEDNHLKRFTTEEWVNQMIA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IEE8-1", "uniprot_id": "SN12L_HUMAN", "id": "Q6IEE8-1", "name": "Schlafen family member 12-like", "aln": "---------------------------------------------------------------------------MDLARKEFLRGNGLAAGKMNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLL--QRITEILPQYVSAFANTDGGYLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHM-------------VQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIF-----LFVCLFRFCLFVCWFVCFFLR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A2D6-1", "uniprot_id": "D4A2D6_RAT", "id": "D4A2D6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MGISVDLEAEYAKLGLNLGAITLGEKDRRKMKNSHLRKKENENISLAVCALLNSGGGAIKVKIENENYSLTRDGLGLDLETSLCKCLPFVQWYLDFTESKGYIYIYVRAWSQEIFGLPIGTLSTNLYVRVVSSSVQVSADAALQFLQDLEEAGGRPRVRPELPARKACPGVEGECHQEDLAAAFFNKTEFQYEETFFFTRSRYVEVTSLSVKRLR--KRIREILPRTVSAFANTDGGYLFIGLDGKKQQIIGFEAEKSDLVHLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAACSYVCALRVERFCCAVFAAEPESWHVEDSCVKRFAAEDWVRLQMGSREAWKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1L1STQ7-1", "uniprot_id": "A0A1L1STQ7_MOUSE", "id": "A0A1L1STQ7-1", "name": "", "aln": "MPGASEMKDGPEQEQRHRAGHTWKHGIRASSWLAVGNSQEKSPSVDCRSSHRTLGFSRTGVCLHTAILPTEDNGLNLWKQKGLHLGNRGSDWKTNIIVDQDTDYAELVLFIGEITLGEKNRNSMKDIQLRRKEAKSILQAVCTLLNSGGGVVKAHIKNQNYSFTRDGMGLDLVNSLPGIMHLPHDYLDFMQHKDYFFVFVKPLKPNQKGPGITTLKTNLYRRINSISDEVKVANAVQLLKSRTDPEEKAESRPSSPGKIVCNETLNEC------LSLFNRDWLAYEETFCFTKSIHAEVKLTPKEKIFPKEKILELLPQTVSAFANTDGGFLFIGLDGKTQQIIGFEAEKSNLVLLESEIEKCIQQLPVTHFCGEKEKIKYTCKFIEVRKSGAVCAYVCALRVERFCCAVFAAEPESWHVEGGCVKRFTTEEWVKRQMDATAVMPG-------------------------------------KVICCPEALYMKPFSQHEGYEHLVRTELGSLLKGTLVISKSWALDLGLQEKQEVIWDVLHISQGSLLTLYVFVQGDENLEGNSSLLGELGAELKGYYKQIALTLKQMLLNHCGYTAEIGIIVKITYLGH--KTMCLYDTSTKIRYPQKYYLS-AKAVKDLEKALVEILGSYESFYSLPRRNWDSFMSAFLNVGSYIVPVLRNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4S0-1", "uniprot_id": "A0A0G2K4S0_RAT", "id": "A0A0G2K4S0-1", "name": "", "aln": "-----------------------MAGNLPRLVEDVNPQTFTEPSVQLKCPGNIFQGGR-----HAKPGSWKDS------QKGFHLGSRDSNCKMSITVDQDTDYAELVLSIGEITLGEKTRKSMKDSQRRKREAKTFQQAVCTLLNSGGGVAKARIKNQNYDFSRDGVGQDLENFLPHILDFPHEYLDFKQVKDYFLMFVKAWKLKQKGPGITTLKTNLYIRSISSSIELKAVNAVKFLKS----------RLSSPGTIVCNEVLNEC------LNLFNRDCFTCKEKFCFTKATHAEVKLTPKE------NILEILPQTVSSFANADGGYLFIGLDGKTQEIIGFEAEKSDLVHLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAACSFVCALRVERFCCAVFAAEPESWHVEDSCVKRFTAEDWVKRQMDGPALISG-------------------------------------KVISSPEALCGKLFSTQEAHEQLLWAQLDSLPKGTLVVTKRWALDLPLQDKHGVILDTLHIPQDSLLTLHGFVLGGEDLEDDSTLLRELGAELKGYYKQTAVTLKQTLANHGSYTEKIGIAIKITYLGHN-KAVSLYDSSSKIHYPTKYYLT-TETAKNLEKALAEILGS---------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . * * * :*** : *..*:: : * :: ... *:*:*:* * * *.. :* .*. :.*:* ** . : * * : . : *:. . . * *: .*: * : : :. * ::*:. . * :*:: : *.: *:.: .* . : .: *:**: **:***:***:**:**: ::::**:*::. **. ::.* :*** *** *: .*:* ***: * . * *.:* ************* :*:****:.. :*::: ::*:. : ", "identical_positions": 93, "similar_positions": 104, "identity": "13.56%" }, { "cls_id": "homologset.agr.HGNC:3393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PL45-1", "uniprot_id": "A0A8M9PL45_DANRE", "id": "A0A8M9PL45-1", "name": "receptor protein-tyrosine kinase", "aln": "---------------------------------------------MNILGLYSQMPKFTAIMDIIRLLWIIRL-----VWAVEDVLMDSTTATAELGWTIYPSLG------WEEVSGYDENMN--TIRTYQVCNVFDANQNNWVRTKYIRRRGAQRIHVEMKFSVRDCSSIPKVPGSCKETFNLYYFESDSDTATKVYPAWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGACMSLIAVKVFYRKCPRIIRNGAIFQETLSGAESTSLVSARGTCVPNGEEVDVPIKLYCNGDGEWLVPIGRCVCKAGHESVDNGTMCKACPFGSFKASQGDQQCLQCPINSRTSSEGATSCVCRNGYYRTDSDPLQMPCTTVPSAPQ-RVISSVNETSLRLEWDVPKESGGREDVVYNIICKSCGSGRGACTRCGDNVQFVPRQLGLTEPRIHISDLLAHTQYTFEIQAVNGVSDQSPYS--------------------------------PQFTAVNITTNQAAPSAVSIMHQVSRAVDSITLSWSQPDQPNGVILDYELQYYEK-NAVESNSSLLRSQTNTAVIRGLKSGTIYVFQVRARTVAGFGRFSGKMYFQTMTEEEYNSSLQEKLPLIIGSAAAGVVFLIAVVVLIIVCNR-RGSDRTDSEYT-----------------------DKLQHYTSGHMSPGMKIYIDPFTYEDPNEAVREFAKEIDVTCVKIEQVIGAGEFGEVCSGNLRLPG--KREILVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNIIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLCDMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSSSDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNNRPKFSQIVNTLDKMIRNPGSLKATTPLSSGVHLPLLDRSTPDFSSFSTVDEWLDAIKMSQYKENFANEDLTTFEAVSQMTMDDILRVGVTLAGHQKKILNSVQMMRAQMNQIQSVEV---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2CEJ3-1", "uniprot_id": "A2CEJ3_DANRE", "id": "A2CEJ3-1", "name": "receptor protein-tyrosine kinase", "aln": "------------------------------------------------------------MMDILWILWTLPS-----VLAIEEILMDSTTATAELGWTVYPVSGTSDSS-WEEVSGYDENMN--TIRTYQVCNVFDANQNNWVRTKYIRRRGAQRIHVEMKFSVRDCSSIPRVPGSCKETFNLYYYESDSDTATKTFPPWMENPWIKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRNGFYLAFQDYGGCMSLIAVRVFYRKCPRTIRNGAIFQETLSGAESTSLVAARGVCIPNAEEVDVPIKLYCNGDGEWMVPIGRCMCKAGHEAVENGTVCRACPSGFFKTAQGDEKCLQCPINSRTTNDGATNCVCRNGYYRTDSDPLEMPCTTVPSAPQ-NVISSVNETSLMLEWNPPRETGGRDDVVYNIICKSCGGGRGGCTRCGDNVQFIPRQLGLTESRVFISDLLAHTQYTFEIQAVNGVSDQSPYS--------------------------------PQYTSVNITTNQAAPSTVSIMHQVSRTIDSITLSWSQPDQPNGVILDYELQYYEK-DQTEHNSSMVKSQTNTAVIRGLKPGGIYVFQVRARTVAGFGRYSGKMYFQTMTEEEYNTSIQEKLPLIIGSAAAGLVFLIAVVVIIIVCNR-RGFERADSEYT-----------------------DKLQHYTSGHMSPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGNLKLPG--KREMFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIASGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNNRPKFSQIVNNLDKMIRNPNSLKAMTPLSSGVHLPLLDRSVPDFSSFSSVDDWLDAIKMGQYKDNFANGNFTSFDLVSQMTMEDILRVGVTLAGHQKKILNSVQMMRAQMNQIQSVEV---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29323-1", "uniprot_id": "EPHB2_HUMAN", "id": "P29323-1", "name": "Ephrin type-B receptor 2", "aln": "----------------------------------------------------------MALRRLGAALLLLPL-----LAAVEETLMDSTTATAELGWMVHPPSG------WEEVSGYDENMN--TIRTYQVCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQ-AVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFS--------------------------------PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEK-ELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNR-RGFERADSEYT-----------------------DKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPG--KREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEGQPLARRPRATGRTKRCQPRDVTKKTCNSNDGKKKGMGKKKTDPGRGREIQGIFFKEDSHKESNDCSCGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54763-3", "uniprot_id": "EPHB2_MOUSE", "id": "P54763-3", "name": "Ephrin type-B receptor 2", "aln": "----------------------------------------------------------MAVRRLGAALLLLPL-----LAAVEETLMDSTTATAELGWMVHPPSG------WEEVSGYDENMN--TIRTYQVCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDLATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRNGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQ-AVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFS--------------------------------PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEK-ELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIKEKLPLIVGSSAAGLVFLIAVVVIAIVCNR-RGFERADSEYT-----------------------DKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPG--KREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEV---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09759-1", "uniprot_id": "EPHB1_RAT", "id": "P09759-1", "name": "Ephrin type-B receptor 1", "aln": "-----------------------------------------------------------MALDCLLLFLLASA-----VAAMEETLMDTRTATAELGWTANPASG------WEEVSGYDENLN--TIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKAGYE-PENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPR-NVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFP--------------------------------PQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEK-EHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSR-KRAYSKEAVYS-----------------------DKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPG--KREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEES-FTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFD--AATREPPPWQTDSYRLIARIAAGEGRFNQNSD---VDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYL-CKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTR---GGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD-GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: :: * * * * * * * * : : :: . *:* **:* . ***: : :* * .*:*:: *::*::**** :* . ******.* ::* * **: . * .: : ***.*. : : . :.:****:*:. :.:.*.*:**:* *.*:*:::*:*:: .** .* * * ** :* * * : .* *: *.* :.* * *:***:* : * * ****.* .. * ** * **: : * ** **.:.. .:. * * .*:** * .:.* : *:.* .: *::** :.* * .. . .. . . * :. : *. *. ** : * :.* :: ::.* . * **.:*:*:*.*: . : . . : :**:.. *:* :: :: : . *.* :* *.: : **:::: * : * : .: ... : ** . * .***.:* *:* :*. : **: . . :: :* *: .:*::*:: .: : * : : : .**: : . : *:**.******:*:****:*** . :.** :**.****:* *.*::* ::: *******.* :** * ***:************:* *:****:* *******:****:**:*** ***:* .:**: ******:**.**.:************:***::*:**::****** ::: :. * *****:******** :*****:*******:*:*****:******: :*****::**:.****.***** **:*********:*. ** *..**..**:: *:* ** : . . :** . . * :.* **. *** :* . * .: . : :::: ::: :*:**.******* . : : . : ", "identical_positions": 373, "similar_positions": 289, "identity": "31.45%" }, { "cls_id": "homologset.agr.HGNC:33939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZL71-1", "uniprot_id": "D3ZL71_RAT", "id": "D3ZL71-1", "name": "", "aln": "MPGWFKKVWYGLASLLSFSSFLLIIVALALPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHITILLLLFLALALALVSMGFAILNIIQVPYRAVNGPGGICLWNVLAGGVVALAISSFMAAVKFHDLTERIANFQERLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEVKT-KMEEATVTPEDILY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RVW2-1", "uniprot_id": "CLRN2_MOUSE", "id": "B2RVW2-1", "name": "Clarin-2", "aln": "MPGWFKKVWYGLASLLSFSSFLLIIVALSLPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVTILLLLFLALALALVSMGFAILNIIQVPYRAVNGPGGICLWNVLAGGVVALAIGSFMAAVKFHDLTERIANFQERLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKT-KMEEATVTPEDILY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PK11-1", "uniprot_id": "CLRN2_HUMAN", "id": "A0PK11-1", "name": "Clarin-2", "aln": "MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKT-KIEEATVTAEDILY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5K7-1", "uniprot_id": "B8A5K7_DANRE", "id": "B8A5K7-1", "name": "", "aln": "MPTLWKQIVFSFASILSIGSVVLLVVALSTERWVTGTTLCQTGVDLVNASRPELEQFTGHIYYGLFQGGKTRRCGLGIRRAKIYIFPKLIKKINSGLHMIIIFFLFTAIGFAVVSLAFCIYNARKVPYQSIKGPFGLYIWNFIAALFSAMGFACFLAAIQCHKLTEHVANYSESLFTLVILEENLGFSFWLVVASAVTHGANILVVASSKIHLPKIQTKKPEEPTATGEDFLY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*: :.:**:**:.*.:*::*** :*::*. ***********: ** :* *.******:* *.*:**** *:::: ***:*:*::*:***: *:::** *:.:*:**:.*.* * :***:::.** *: :**.:*. . *:.:..*:**:: *.***::**:.* ** :*::**: ***: **** :*.**::*** *:* **:::* * **.*.* **:**", "identical_positions": 114, "similar_positions": 82, "identity": "48.93%" }, { "cls_id": "homologset.agr.HGNC:3394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH39-1", "uniprot_id": "D3ZH39_RAT", "id": "D3ZH39-1", "name": "Ephrin type-B receptor 3", "aln": "---------------------------------------------MAGARPPP------GLLPLLAPLLLP--LLLPAGCRALEETLMDTKWVTSELAWTSHPE------SGWEEVSGYDEAMNP-IRTYQVCNVRESSQNNWLRTGFIWRREVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDE-SFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIANAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKETQCRACPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDTADSACTTVPSPPRGV-ISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCRGSSGAGGPATCSRCDDNVEFEPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRY--------------------------------AAVNITTNQAAPSEVPTLHLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSKG--I-ASTVTSQKNSVQLDGLQPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSTVAGFVFMVVVVVIALVCLR-KQRQGPDAEYT-----------------------EKLQQY----VAPRMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAG-----------------------------EFGEVCRGRLKLPG--RREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLVQEEATERDLREGRAGQAGDQGSGSSLSHKVKGMSPSNQGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAPSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVGAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54754-1", "uniprot_id": "EPHB3_MOUSE", "id": "P54754-1", "name": "Ephrin type-B receptor 3", "aln": "---------------------------------------------MAGARPPP------GLLPLLAPLLLP--LLLPAGCWALEETLMDTKWVTSELAWTSHPE------SGWEEVSGYDEAMNP-IRTYQVCNVRESSQNNWLRTGFIWRREVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDE-SFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIANAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRACPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGV-ISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCRGSSGAGGPATCSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRY--------------------------------AAVNITTNQAAPSEVPTLHLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSKG--I-ASTVTSQKNSVQLDGLQPDARYVVQVRARTVAGYGQYSHPAEFETTSERGSGAQQLQEQLPLIVGSTVAGFVFMVVVVVIALVCLR-KQRHGPDAEYT-----------------------EKLQQY----IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAG-----------------------------EFGEVCRGRLKLPG--RREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSL---------------------------------------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVTASAPSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVGAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILCSIQDMRLQMNQTLPVQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54753-1", "uniprot_id": "EPHB3_HUMAN", "id": "P54753-1", "name": "Ephrin type-B receptor 3", "aln": "---------------------------------------------MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPE------SGWEEVSGYDEAMNP-IRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDE-SFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGV-ISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHG---AGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRY--------------------------------AAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEG--I-ASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLR-KQRHGSDSEYT-----------------------EKLQQY----IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAG-----------------------------EFGEVCRGRLKQPG--RREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSL---------------------------------------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IDQ0-1", "uniprot_id": "A0AC58IDQ0_DANRE", "id": "A0AC58IDQ0-1", "name": "Ephrin type-B receptor 3", "aln": "--------------------------------------------------------------MTMDYLLFLCGFLLPLSS-AVEETLMDTKWAMTELAWTSHPE------TGWEEVSGYDDAMNP-IRTYQVCNVRELNQNNWLRSDFIPRKDVLRVYVEMKFTVRDCNSIPNIPGSCKETFNLFYYESDSDSATATSPFWMENPYVKVDTIAPDE-SFSMLESGRVNTKIRSFGPLSKAGFYLAFQDLGACMSLISVRAFYKKCSTTIANFAVFPETATGAEATSLVIAPGTCVPNALEVSVPLKLYCNGDGEWMVPVGSCTCMAGFEPAVKETQCQACSPGTFKSKQGEGLCSPCPPNSRTSSGAASICSCRTGYYRADSDSPDSGCTTVPSAPRNV-ISSVNETSLILEWSEPRDQGGREDLLYNVICKKCLP-----ERGTCTRCDDNVDISPRHLGLTERHVTIRNLQAHTQYSFEIQAVNGVASKSPYAPQF--------------------------------ASVNITTNQAAPSAVPTVHLTGASANTMTLSWLPPEKPNGIILDYEIKYHEKDQGEAI-AHTMTAQHSYARIDGLKPGTPYVVQVRARTVAGYGRYSSPTDFGTN-HQADADKALQEQLPLIVGSLTAGLVFIIVVVVIAIVCLR-KQRNGSESEYT-----------------------EKLQQYKSPIVTPGMKVYIDPFTYEDPNEAIREFAKEIDVSCVKIEEVIGAGNQHQKLLSNRGKTARHTQAIPLEDFTSSGEFGEVCRGRLKLPG--RREIIVAIKTLKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPTDPTYTSSL---------------------------------------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVKERNLRPKFSQIVNTLDKLIRNAASLKVVTSTHSGASQPLLDRCVPDYTTFTTVGDWLDAIKMSRYRDNFLNAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILGSIQDMRLQMNQTLPVQV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O13147-1", "uniprot_id": "EPHB3_DANRE", "id": "O13147-1", "name": "Ephrin type-B receptor 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLLVLDLIIQER-GES------------------------------------------------------FSHTVTAQHTSAKVEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKAGTVYSVQVRART-VAGYGRYS-----------------------------------NPVDFST---------SLYVCPVSSSSTSMHLRRREELTTTTTGLK--------------------------------------------------SREERFQKS---DDPERSVQDLLPLIVGSASAGFVVILAMIVIAVVCLR-RQRTGSELEYT-----------------------EKLQQY----VSPGVKVYIDPFTYEDPNEAVHEFAREIDISCVKIEEVIGAG-----------------------------EFGEVCRGRLKQAG--RKETTVAIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRLNDGRFTVTQLVGMLRGIAAGMKYLSDMNYVHRDLAARNVLVNSNLVCKVSDFGLSRFLDDNSSDPTYTSSL---------------------------------------GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVMNAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVSTLDKFLRNAASLKVLTSTHSG----------------------------------------------------DLCRIGGTLPGHQRKSIGDAQDIKQQMSQTLPIRV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTR-EATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFD--AATREPPPWQTDSYRLIARIAAGEGRFNQNSDVDINTEVKS-IAVNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETP-TYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVY-----KIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDS-VQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGG-----------------------------EFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYT-TRG----------------------------------------GKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILDGQ-RGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . . * .* *. . : * . * *:.:::* . *: . : ::* .: : : . : . : * . . : :*.*: :*.:.:: .:: :: :* ::: . : : * :**: : : *:**.******:*::***:*** . :.** :**.* ***:******* . :: ******* * :*: * ***:************:* *:**:*:* **:*:**:*** :**:***:***:* . **: ******:**.***:************:***::*:**::****** ::: .:*. : ****:*********:*************:*:*****:******: *****::::*:.****.***** .*:****:** ::*. ** *..**.***:: *:. ** . .: .. :* :* ** ***:* : . ::: : ", "identical_positions": 215, "similar_positions": 143, "identity": "18.1%" }, { "cls_id": "homologset.agr.HGNC:33940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0P8-1", "uniprot_id": "NPS_MOUSE", "id": "P0C0P8-1", "name": "Neuropeptide S", "aln": "MIGSLKLSFVLALSLSVMHVLWCYPVLSSKVPGKPDYFLILLSSCPARLEGSDRLAFLKPILEKTSMKRSFRNGVGSGAKKTSFRRAKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C0P7-1", "uniprot_id": "NPS_RAT", "id": "P0C0P7-1", "name": "Neuropeptide S", "aln": "MIGSLKLNLILALSLSVVHVIWSYPVLSSKVPGKPDYFLILLSTCPARLEGSDGLAFLKPILEKTSMKRSFRNGVGSGVKKTSFRRAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C0P6-1", "uniprot_id": "NPS_HUMAN", "id": "P0C0P6-1", "name": "Neuropeptide S", "aln": "MISSVKLNLILVLSLSTMHVFWCYPVPSSKVSGKSDYFLILLNSCPTRLDRSKELAFLKPILEKMFVKRSFRNGVGTGMKKTSFQRAKS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*:**.::*.****.:**:*.*** ****.**.*******.:**:**: *. ********** :*********:* *****:***.", "identical_positions": 62, "similar_positions": 21, "identity": "69.66%" }, { "cls_id": "homologset.agr.HGNC:33941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9N7-1", "uniprot_id": "A0ABK0L9N7_RAT", "id": "A0ABK0L9N7-1", "name": "", "aln": "MSSAAKSQVLEETAPGCEEEPKGKTLFTWGSLFGHRSEKIVFTKGDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTFFMDVPVIGGSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTVGVLLYNKARQYQQETMQSLVTATSQGPNDDTEPLVSQDSRQHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C811-1", "uniprot_id": "S35E2_MOUSE", "id": "Q8C811-1", "name": "Solute carrier family 35 member E2A", "aln": "MSAAAKSQVPEEAAPGCEEEPKGKTLLTWGSLFGHRSEKIVFTKGDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTFFMDIPVIGRSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTLGVLLYNKARQYQQETMQSLVTATSRNPEDDTEPLVPQDSRQHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CK96-1", "uniprot_id": "S352B_HUMAN", "id": "P0CK96-1", "name": "Solute carrier family 35 member E2B", "aln": "MSSSVKTPALEELVPGSEEKPKGRSPLSWGSLFGHRSEKIVFAKSDGGTDENVLTVTITETTVIESDLGVWSSRALLYLTLWFFFSFCTLFLNKYILSLLGGEPSMLGAVQMLSTTVIGCVKTLVPCCLYQHKARLSYPPNFLMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNVLGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVAMLVPARVFFTDVPVIGRSGKSFSYNQDVVLLLLTDGVLFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSVIVFGNKITSLSAVGTALVTVGVLLYNKARQHQQEALQSLAAATGRAPDDTVEPLLPQDPRQHP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::.*: . ** .**.**:***:: ::**************:*.**..:*.:***********************:*********************** ***************:***** :*********:********:******************************************************************************:**********************************************:*:** .** *:**** *******.**:********.************************************:************:** ***:**********:***::***.:**.: *:* .***:.**.*** ", "identical_positions": 345, "similar_positions": 47, "identity": "85.19%" }, { "cls_id": "homologset.agr.HGNC:3395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDA4-1", "uniprot_id": "M0RDA4_RAT", "id": "M0RDA4-1", "name": "Ephrin type-B receptor 4", "aln": "---------------------------------------------------------MELR---------ALLCWASLATALEETLLNTKLETADLKWVTYPQA----EGQWEELSGLD-EEQHSVRTYEVCDMKRPGGQAHWLRTGWVPRRGAVHVYATIRFTMMECLSLPRASRSCKETFTVFYYESEADTATAHTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNIKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCSRLVTNLTYFPETVP---RELVVPVAGSCVANAVPTASPS--PSLYCREDGQWAEQQVTGCSCAPGYEAAEGNKVCRACGQGTFKPQIGEEPCLPCPANSHSNNIGSPVCLCRIGYYRARSDPRSSPCTTPPSAPRSV-VHHLNGSSLRLEWSAPLESGGREDLTYAVRCRECR-PGGSCLPCGGDLTFDPGPRDLVEPWVAIRGLRPDVTYTFEVAALNGVSTL-----------------------ATGPPPFEPVNVTTDREGRTGFLSPAVPPAVSDIRVTRSSPSSLILSWAIPRAPSGAVLDYEVKYHEKG-AEGPSSVRFLKTSENRAELRGLKQGASYLVQVRARSEAGYGPFGQEHHSQTQLDESESWR--EQLALIAGTAVVGVVLVLVVIIIAVLCLRKQSSGREVEYSDKHGQYLIGHG---------------------------TKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPG--KKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQP-HYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFEVVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQAKPGAPGGTGGPTQQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54761-1", "uniprot_id": "EPHB4_MOUSE", "id": "P54761-1", "name": "Ephrin type-B receptor 4", "aln": "---------------------------------------------------------MELR---------ALLCWASLATALEETLLNTKLETADLKWVTYPQA----EGQWEELSGLD-EEQHSVRTYEVCDMKRPGGQAHWLRTGWVPRRGAVHVYATIRFTMMECLSLPRASRSCKETFTVFYYESEADTATAHTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNIKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCSWLITNLTYFPETVP---RELVVPVAGSCVANAVPTANPS--PSLYCREDGQWAEQQVTGCSCAPGYEAAESNKVCRACGQGTFKPQIGDESCLPCPANSHSNNIGSPVCLCRIGYYRARSDPRSSPCTTPPSAPRSV-VHHLNGSTLRLEWSAPLESGGREDLTYAVRCRECR-PGGSCLPCGGDMTFDPGPRDLVEPWVAIRGLRPDVTYTFEVAALNGVSTL-----------------------ATGPPPFEPVNVTTDR---------EVPPAVSDIRVTRSSPSSLILSWAIPRAPSGAVLDYEVKYHEKG-AEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESESWR--EQLALIAGTAVVGVVLVLVVVIIAVLCLRKQSNGREVEYSDKHGQYLIGHG---------------------------TKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPG--KKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQP-HYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFEVVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQAKPGAPGGTGGPAQQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54760-1", "uniprot_id": "EPHB4_HUMAN", "id": "P54760-1", "name": "Ephrin type-B receptor 4", "aln": "---------------------------------------------------------MELR---------VLLCWASLAAALEETLLNTKLETADLKWVTFPQV----DGQWEELSGLD-EEQHSVRTYEVCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPS--PSLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSV-VSRLNGSSLHLEWSAPLESGGREDLTYALRCRECR-PGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSL-----------------------ATGPVPFEPVNVTTDR---------EVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKG-AEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWR--EQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHG---------------------------TKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPG--KKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQP-HYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQAKPGTPGGTGGPAPQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O73878-1", "uniprot_id": "EPB4B_DANRE", "id": "O73878-1", "name": "Ephrin type-B receptor 4b", "aln": "---------------------------------------------------------MDRVCWIMALSWFWMVSTGLVS-AEEEVLMNTKLETSDLRWTIYPSG----DPEWEEMSGLD-EEGNSVRTFQVCPMD--SSVSHWLRTRFIPRHGASQVYVEIRFTMMECSAMPASFRTCKETFNLYYYQSDEDTASATHPAWMENPYSKVDTVAADFLLRR--GGER--KSNVKTVRVGPLSKKGFYLAFQTQGACMALLSVRVFFKKCPAVSRAFSSFPETLP---HSLVQQAEGVCVDNSAPTGQSTAPPTMFCGEDGQWVGPPSSTCACKPGYEPVDSD-RCRACGLGQYKASVGGSLCRVCPDNSNTHFAGSSLCVCRPGYHRATSDLPDSACTKPPSAPRSI-IYQINDTVVTLEWSEPLDRGGRSDLSYSVECMHCR--GSLCVQCADSITYRPGQMGVPGRRVIIRGLLPHTTYTFTVLAQNGVSAV-----------------------SHTSPASSSVNITTSR---------DVAVPVSGIRRIKASESSVSISWTVPPQTQHSIQDYQLRYSLK---GQDDGWQYVSSRSSSVVLNDLSRASQYQVQVRARTAAGYGHFSSAVSISTLPDDEESP---SRLMLTGVLVAIGLLILIAVVIVAVFCFRRSTRRRDPDP-DKSGQFLMGQG---------------------------IKVYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVCRGRLKVPG--KKENYVAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMILTEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAARNILVNSNLVCKVSDFGLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPECPASLHQLMLDCWQKERSSRPRFCAIVSALDRLIRNPASLKITGRIPDGPSHPLLDQRAPPPLSHCSSVADWLRAIKMERYEDAFMQAGFTAIQHITHISTEDLLRIGVTLAGHQKKILSSVQTLRIHG-----GSLRY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O73875-1", "uniprot_id": "EPB4A_DANRE", "id": "O73875-1", "name": "Ephrin type-B receptor 4a", "aln": "---------------------------------------------------------MELFSRNVAAFWIILLEFLLGSVAEEEVLMNTKTETSDLKWTTHSRS----KPEWEEVSGLD-EENNSVRTYQICQAD--GSSSHWLRSKLIERRGASQVYVELFFTMVECSSRNTHHRSCKETFNLYYYQSDTDDATATHPAWMENPYTKVDTVAADFLLRK--GGEK--KVNVKTLRLGPLSKRGFYLAFQAQGACMALLSVRVFFKKCPALTRSLSVFPETVP---RSLVQEAVGQCVANAAQPGPSPRPPKMFCGEDGQWVDQPTTTCTCLPGFEASHGELECRACPVGLFKMGSGTGPCSVCPENSQTGETGSAACVCRSGFYRALSDSADTPCTRPPSSPRSP-VPQVNDTSLTLEWSEPLDSGGRSDLSYSVECRMCSTPGSPCTLCSDGVNYRPSQTGIQGRRVSIWGLRPHTTYSFTVMALNGVSAQ-----------------------SQQGPAGETINITTSP---------NVPVLVSGLRKSTATESSLTLYWNTPTQSHYRILQYQIRYCEKERGSEENSCHYMESNNNEVVLSDLRRATQYEVQVRARTFAGYGSFGKAILFRTLPDEDDSS---SPLLVTGILIAMGMLLLIIVIGAAIYCIRKQNNYKDPELSDKNGQYLMGQG---------------------------VKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLRIPG--KKENYVAIKTLKGGYTDKQRRDFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLQENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTCASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKLIRNPASLKITAQEGAGPSHPLLDQRSPLTPSSCGTVGDWLRAIKMERYEETFLQAGYTSMQLVTHINTEDLLRLGITLAGHQKKILSSIEALGIQNKA--PGNVLY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAY-HNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFY--EFDAATREPPPWQTDSYRLIARIAAG-EGRFNQNSDVDINTEVKSIAVN---KKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPT----YLCKGDGKWT-ILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAIN-KSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREI-ENASDAYTTR--GGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILDGQRG--QNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: ::.:: . . : *.*. .. * * * * : . *:: :* . :** : : * .* ::* : **: :* :*****.: :* : * *: *.* :.* : :** * ..: : ::*:: :. * *.*:**: ****:::*:::::: .*. : :: * ** . :: * ** :: .. * **:*. * * .*:*. : * * * :* * ** **:: **. * * *:.* .* .* **::* . : :: : :.** * . . .. : : * *. .: : *. . : : .* * **:. : * *.** : . . ::.*. : * .:* : .. : * * . : *:::: * . :.: .. . : .* . :.* .***.:: *:* :.. * . . : . . . *::::: .: :: :* . . : :. . : *:**.******:*:****:***.. :.** :**.****:******: * :: ******* * ::: * :**:********:***:* *:*::* * ****:**:****:**:***:***:* :**: ********* **::*.:*********:***::*:**::****** : **:**. * *****:**************.***.****:*:*****:******: ******::**:.****.* :** *:*********:*. ** * :**:**.: *:* ** . . .: :** : . :. **. *** ** . * *. : ::::.:::* :*:**.******* . . : ", "identical_positions": 322, "similar_positions": 274, "identity": "28.5%" }, { "cls_id": "homologset.agr.HGNC:3396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0K7-1", "uniprot_id": "EPHB6_RAT", "id": "P0C0K7-1", "name": "Ephrin type-B receptor 6", "aln": "-------------------------------------------------MASENTAGSGSR-VAGMVYSLWLLVLGPSVLALEEVLLDTTGETSEIGWLTYPPG------GWDEVSVLDDQR-RLTRTFEACHVAGLPPGSGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQADEPD------SPDSISAWHLKRWTKVDTIAADESFPASSSSSS------WAVGPHRTDQRVGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVKLFSYTCPSVLRAFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGRWMVAVGGCRCQPGHQPARGDKLCQACPEGSYKALPGNVPCSPCPARSHSPDPAAPVCPCLQGFYRASSDPPEAPCTGPPSAPRELWFEVQGS--ALMLHWRLPQELGGRGDLLFNVVCKECGGHKEPSSGG--MCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQ--------------------------------AAAINVSTSHEVPSAVPVMHQVSRAANSITVSWPQPEQTNGNILDYQLRYYDQAEDESH-SFTMTSETNTATVTRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPEKLSLVIGSILGALAFLLLAAITVLAVIFQR-----KRRGTGYTEQLQQYSSPGL----------------------GVKYYIDPSTYDDPCQAIRELAREVDPTYIKIEEVIGAGSFGEVRRGRLQPRG--RREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTRSRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---------------PQGSSSLLRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMSDQEVLNAIEQEFRLPPPPGCPTGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGSSGDRPSQALLNPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLSTFSDVAQLSLEDLPGLGITLAGHQKKLLHNIQLLQQHLRQPGSVEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08644-1", "uniprot_id": "EPHB6_MOUSE", "id": "O08644-1", "name": "Ephrin type-B receptor 6", "aln": "-------------------------------------------------MATEGTTGSGSRVVAGMVCSLWLLVLGSSVLALEEVLLDTTGETSEIGWLTYPPG------GWDEVSVLDDQR-RLTRTFEACHVAGLPPGSGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQADEPD------GPDSIAAWHLKRWTKVDTIAADESFPASSSSSS------WAVGPHRTGQRVGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVKLFSYTCPSVLRAFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGRWMVAVGGCRCQPGHQPARGDKLCQACPEGSYKALAGNVPCSPCPARSHSPDPAAPVCPCLQGFYRASSDPPEAPCTGPPSAPRELWFEVQGS--ALMLHWRLPQELGGRGDLLFNVVCKECGGHGEPSSGG--MCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQ--------------------------------AAAINVSTSHEVPSAVPVMHQVSRAANSITVSWPQPEQTNGNILDYQLRYYDQAEDESH-SFTMTSETNTATVTRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPEKLSLVIGSILGALAFLLLAAITVLAVIFQR-----KRRGTGYTEQLQQYSSPGL----------------------GVKYYIDPSTYDDPCQAIRELAREVDPTYIKIEEVIGAGSFGEVRRGRLQPRG--RREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTKSRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---------------PQGSSSLLRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMNEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGGSGDRPSQALLNPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLSTFSDVAQLSLEDLPGLGITLAGHQKKLLHNIQLLQQHLRQPGSVEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15197-1", "uniprot_id": "EPHB6_HUMAN", "id": "O15197-1", "name": "Ephrin type-B receptor 6", "aln": "-------------------------------------------------MATEGAAQLGNR-VAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPG------GWDEVSVLDDQR-RLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPD------SPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGS--ALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQ--------------------------------AAAINVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESH-SFTLTSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQR-----KRRGTGYTEQLQQYSSPGL----------------------GVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRG--RREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHS---------------PQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKS8-1", "uniprot_id": "A0A8M2BKS8_DANRE", "id": "A0A8M2BKS8-1", "name": "receptor protein-tyrosine kinase", "aln": "--------------------------------------------------------------MEMWRIFLSVSLVVQHSSAEEVMLLDTSESTAELGWTTYPDT------GWDEVSVLDDKG-RLMRTFEVCNVNQNP--RLQDNWLATPFLYRQSAPRIFVTLRFSVRDCASLRSPSPTCRETLTLYYKQADSQRELERTWAAEASSGETREGWVKIDTIAADKSFSRVEPSLP-----------HQYKSENARRINVKTRSFAPLTRKGFVLAIVDSGACVSLMGVSIFYRRCPATSRFLAFYPATPS-GAEPTSLVPVTGTCVPHSQSQ--------GGTAPRMHCNTEGEWLVPVGGCTCDAGYEPNHNGSACLVCPIGSYKAVAGSVSCTECPANSRTSSEGAKVCECRSGYYRAPADANTTACTSSPSAPLALSWEYESSEGGVSLRWRPPADMGGRTDVWYGVVCRICP---SATSTPPSMCSWCGETVTYSPSQNGLKQTRVTLKNLLTRVTYLIQVQAMNEVSALSPFPPQ--------------------------------FASINFTTSQSVPSEVPMLHQLSRVQDSITLSWPQPDRPNGDILEYQLRYYDKGSDEDS-ALSMYSETNTVTVTGLIPGSIYAFQIRARNERGFGPYSHTIYFSTLASEGQSKQIQNRLPLMIGSVMGGAAFLLVVIAIIIVFVFRS-----KRRESPYSDRLQRYISNRG----------------------GVKYYVDPSTYEDPSEAVKEFAREIDPAHLKIEEVIGAAQFGEVSRGRYRPIG--RREALVAVKTLRWGVTEREKNVFLSEAGVLGQFDHPNVLKLEGVITRTPPERIITEFMENGPLDAFLRENEDQFSVLQLVGMVRGVGAGMRYLSERNFVHRDLAARNVLVNSNLVCKVSDFGLSRLMRGLDHNMPTYTASLGSKIPVRWTAPEAFQHRKFSSASDVWSFGILMWEVMSYGERPYWDMSNQEVMKAVVDQYRLPAPNGCPPALHSLMLQCWQADRQDRPGFDSLLSSLDRLIRHPASLKAEHS---RPTQPLLSPTPTDLSSVNTVGDWLTVLKMDRYKDAFERAQYHSLESVSMLTMQDVQALGVNLLGHQRKIVNAAKQLRTHLTQ-GHVEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHN----VNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAAT--------REPPPWQTDSYRLIARIAAGE---------------------GRFNQNSDVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPT-GREITIIEKQNGTCVDNAEPY----------ETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQT-SAIISWSAPAKNE-------SFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN----ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD-GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : ::* : : : * ** ** * *. * *:: .*.* :*** : *: * .* * .: ::*::* *: : . :*:**::* : : : . . : : ***.: .. :*.: :*:. :.::*. .*: * ***::::.* :: **:. . :* : * : * : : **** :::. .* *: :*.* : .*** *..*::* .. * ** * :*: . *: **..*.:.. .: .* * .*:** . * .* ..*:** * .. . : * * . .. .. . * * * :.* :.:::: : .* . ..* ::::*:* ** :. : * * .:*. : * * :: :: . .. :.* :* :.: : *::*:: : . : :: :: ... :. * . *.**:*.:. *.*.*. :* .** . : :: :: *::: . **:: : .: .:: : : * * . : *:** **:** :*::*:***:*. ::.** :** ..**:* :** : :: **:::* * :* : ** .*.::***:***:: *:**:*:: * ::** ** *.**:*** .:.:*. ***: * **:.:.* ***. :*** *:*:.****::*:**:: :* * . * . :**:***.: . *.:::*****:*:::************: .:*:*:::: . :***.* .** .*: ***: ** :* ** * .:::::*.: *:* :* : : :* . . : ** : :. * . *.. . ..:: *: ::: :*:.* ***:*::: : * : ", "identical_positions": 251, "similar_positions": 334, "identity": "21.58%" }, { "cls_id": "homologset.agr.HGNC:33983", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GC89-1", "uniprot_id": "A0A8I6GC89_RAT", "id": "A0A8I6GC89-1", "name": "", "aln": "MRGNSATQGVGLKTNGARPLFLMTVALQLIRPGNSYQRE-GDGAR-EISYLLSPKLPGTTLDGTLSSSSRKNDSQEGAHPSEALSGSNTLEESAVPGSRCCHNGGTCVLGSFCVCPAHFTGRYCEHDQRHRDCGALGHGAWTLHSCRLCRCIFSALYCLPRQTFSHCDLKSFLSSGARGSRACSIPRLLLLVLCLLLQVVCGW------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97766-1", "uniprot_id": "CFC1_MOUSE", "id": "P97766-1", "name": "Cryptic protein", "aln": "MRANSPTQGISLKMHQARPLFLVTVALQLIGLGYSYQSE-GDGAR-EVSNILSPVIPGTTLDRTLSNSSRKNDIPEGARLWDSLPDSSTLGESAVPVSRCCHNGGTCVLGSFCVCPAYFTGRYCEHDQRRRDCGALGHGAWTLHSCRLCRCIFSALYCLPHQTFSHCDLKSFLSSGARGSRECSIPSLLLLVLCLLLQGVAGKG-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CG36-1", "uniprot_id": "CFC1B_HUMAN", "id": "P0CG36-1", "name": "Cryptic family protein 1B", "aln": "MTWR----------HHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGEVTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : .* ** :::***:* * *** * :*.* *:: : : :.*: * * .. .. ** :.*. * :: *.* . .***:***************:***********: :**** ******::*:******.**:*** ** .:** *.**:* *:*. . * ****: * **: : ", "identical_positions": 94, "similar_positions": 47, "identity": "40.34%" }, { "cls_id": "homologset.agr.HGNC:33984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1QQY8-1", "uniprot_id": "A0A8M1QQY8_DANRE", "id": "A0A8M1QQY8-1", "name": "", "aln": "--------------MEAEENKVSVWVCREEKLVSG----LSKRTTCADVIRVLLEE-------QNQEQR------------------------------VSLPGSPQSYCIVEKWRGFERILPNKTKILRLWSAWGEEQENVRFVLLKNEASLSSSGPRSAEARVVLSKESPCVYK-GTARVTMALSHEKQRRIVRKAFRKLDKINKKRAQAAS--------------------KDASCMEKMETLVHLVISQDHTIRQQVQRIKELDREIDKYEAKVHFDRMKMHGINYVQDTYLVDA---------------------KNENPDETSPEEALAQFEEYAQR------CEEVIKLQDELAENEALMEGITTEIQEELNQRWMKRRHQELANKDSESTSDEASLRVTTLETQASADPSPDNEVLLEEERIRTQLDTSLYIGLRLNTDLEA------IRNDLSLTEEIWGAKEKELMDLMEKVNSLDFEIDAEGDAELKEENTG----GTDRLVPLKGDNVWVEQARGLSKTCDMNDDDSDTGLSSMHSQDSD-ITPICESLV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BLW7-1", "uniprot_id": "A0A8M2BLW7_DANRE", "id": "A0A8M2BLW7-1", "name": "", "aln": "--------------MEQEESKISVWVCREEKLVSG----LSRRTTCADVVKVLLED-------QNFQQG------------------------------AMLSGPPQSYCIVEKWRGFERILPNKTKILRLWSAWGDEQENVRFVLVRSDASLPNNGPRSAEARVVLSKESPC-----TSRTTMPFSQEKQRRIVRKAFRKLDKINR-RKEEVS--------------------KDKS-AEKMETLVHLIISQDHTIRQQVQRIKELDGEIERFESKVHFDRMKIHGVNYVQDTYLLDQ---------------------GDSS---ARSDAALAQFEEYASR------CDQVIQLQEELTEREALMEILTGEIQEELNHRWMRRRKAELSGKDAESSGEETPLKVSSVAEESLPEHLTDTELQLEEERIKTQLDTSLYIGLRLNTDLET------VKSDLDMSQELLDSKERELRELLEKVHRLD-ELEEKQAEDGKDE-------GEAKTLPS-VDNVWVEQARGMSKTC-TNDDDSDTGLSSMHSQDSDNNAPVCESLV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LNY4-1", "uniprot_id": "A0ABK0LNY4_RAT", "id": "A0ABK0LNY4-1", "name": "", "aln": "--------------MDPSEKKISVWICQEEKLVSG----LSRRTTCSDVVRVLLEDGCRRRCRQRRGQRRGLTEDPSGQLGLPEPPDENDEDDDDAMPQGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWTAWGDEQENVRFVLVRSEASLPNAGPRSAEARVVLSRERPCLARGAPARPSLALTQEKQRRVVRKAFRKLAKLNRRRQQQPSSPCSSTSSSTASSCSSSPRTHESASVERMETLVHLVLSQDHTIRQQVQRLRELDREIDRYEAKVHLDRMRRHGVNYVQDTYLVGADLDLDRPTPEKEPEDATLEEK-TEAAAPLDGEAQAAALEELARR------CDDLVRLQEERAQQEELLERLSAEIQEELNQRWMQRRNEELAARE----------------ESPEPDGGLDGELLLEQERVRTQLSTSLYIGLRLSTDLEA------VKADLDYSQQQRDIKERELQGLLQSLRTFEQTVVRDGTLGSGEP--------SREPQPQTCAEMWVDQARGLAKSCPGNDEDSDTGLSSMHSQDSDSVPPV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BL43-1", "uniprot_id": "RASFA_MOUSE", "id": "Q8BL43-1", "name": "Ras association domain-containing protein 10", "aln": "--------------MDPSEKKISVWICQEEKLVSG----LSRRTTCSDVVRVLLEDGCRRRCRQRRGQRRGLTEDPSGQLELPEPPDENDEDDDDAMPPGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWTAWGDEQENVRFVLVRSEASLPNAGPRSAEARVVLSRERPCLARGAPARPSLALTQEKQRRVVRKAFRKLAKLNRRRQQQPSSPCSSTSSSTASSCSSSARTHESASVERMETLVHLVLSQDHTIRQQVQRLRELDREIDRYEAKVHLDRMRRHGVNYVQDTYLVGAGIDLDGQTPEGEPEDATLEEKGTEPAAPLDSEAQAAALEELARR------CDDLVRLQEERAQQEELLERLSAEIQEELNQRWMQRRNEELAARE----------------ESLEPDGGPDGELLLEQERVRTQLSTSLYIGLRLSTDLEA------VKADLDYSQQQRDIKERELQGLLQSLHTFEQTVVHDGALGSSGP--------SREPQPQTCAEMWVDQARGLAKSCPGNDEDSDTGLSSMHSQDSDSVPPVCESLV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NK89-1", "uniprot_id": "RASFA_HUMAN", "id": "A6NK89-1", "name": "Ras association domain-containing protein 10", "aln": "--------------MDPSEKKISVWICQEEKLVSG----LSRRTTCSDVVRVLLEDGCRRRRRQRRSRRLGSAGDPHGPGELPEPPNEDDEDDDEALPQGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWAAWGEEQENVRFVLVRSEASLPNAGPRSAEARVVLSRERPCPARGAPARPSLAMTQEKQRRVVRKAFRKLAKLNRRRQQQTPSSCSSTSSSTASSCSSSPRTHESASVERMETLVHLVLSQDHTIRQQVQRLHELDREIDHYEAKVHLDRMRRHGVNYVQDTYLVGAGIELDGSRPGEEPEEVAAEAEEAAAAPPLAGEAQAAALEELARR------CDDLLRLQEQRVQQEELLERLSAEIQEELNQRWMRRRQEELAARE----------------EPLEPDGGPDGELLLEQERVRTQLSTSLYIGLRLNTDLEA------VKSDLDYSQQQWDSKKRELQGLLQTLHTLELTVAPDGAPGSGSP--------SREPGPQACADMWVDQARGLAKSGPGNDEDSDTGLSSMHSQDSDSLP-MCESLV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0U4-1", "uniprot_id": "Q9W0U4_DROME", "id": "Q9W0U4-1", "name": "Ras association domain-containing protein 10", "aln": "MQSLPLPGDEAIGLLPSQSESFSIWVNGEEHWISG----ADSSTTCADLICALISY----QIDQKHVLS------------------------------KEEILAPQQFAIVQKQRHYEEYLDSSARLLDVITSPHAMPKEEYQLHLRHLATSSRKQVPTTDKDSGMGSPVDSSRSMRIRRRGKLLSTKTTDNINTKQSKRSRKQQQRNHHLTP----------------------------NESLLTIILAQDETILQQMTMLHEKDRQIFKIEEEKHQVRERELGKNYLLETYLKDLDEPQEKGEDLELFEEMTHIDVDRDFGIMSDSTVQTALNSGTMQDDIRLYWLEKIHEVNKELQCEEELLLSLHSKVRRHQVKRAYQTKSEVLLQIER---------LDTELATQVADIHHVERKLFTANEQLKAKLAVLECLSREFETTVSGGVQEGDVATGSNASAKVQQSQSDDLQHAGNWLHVVKRLFAADHLNRRLTQQALSEKNLTDRLIPSKGISKQMFEVLRSPDPSTSNSVNKKE-LSTRQAISLERDIQHLGTLV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUU9-1", "uniprot_id": "Q9VUU9_DROME", "id": "Q9VUU9-1", "name": "", "aln": "----MAPQQQNSTFIDDNLDSCPSLLNLPESPILPPRRCQNQDTNNNNNNNKQAAFEERLVDESPSVGEPPLAPPIPLAIPMAPAPPHRQACKNKHGRENGNAGQASRRHRSISLYGVNSTVEQGHKEIPIWMDDG-EARYVSGVTNKTTCDDIIKALIDDELRNGNGFYCGNNPKDGGQRKTAAASRDYSDYIITESWGGIERCYDGNMAILPVWRAWSRVHN----ELRISLKHRDSFRDPLAMQLVPHSQSATGFSMYKWLKKLLHLKKGKKTPPKPTKTPPKVPNKLKEKRVHGQKQTMTN--------DLVLVIMPDQLYRGTENTAKSKLYKLAENR-----VSKQRHRRRSRHEITKASVETFRTAIPSECNNNNYNVNNCIRRRKDK---------PLRNSVRYKLASLHADMNVRYEKEHALTRQLSEMCRLYRLQNERYKG---PEMELSVGQLQQNIEAYAEDIIKTEHELLELKNEIKHDISLINNLK--------RLTLEESEADAACKKGAAKITHPLQENENTPQVAKNTQEMQFVDNIYEFCDNNASMLV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. . : * : . *. : . .. . : : . : : : . : : . : . * : . : : : . . :: : :*. * . ::: : : : * : :. : . . .. . ... : : : : . :. . . : : :: :*: :: .:.. : . . : :: . : .. . . . ... *. . .: . : ", "identical_positions": 8, "similar_positions": 100, "identity": "1.41%" }, { "cls_id": "homologset.agr.HGNC:33995", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25007-1", "uniprot_id": "PPIA_DROME", "id": "P25007-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLD-------VVKKIESYGSQSG-KTSKKIIVANSGSL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PHT1-1", "uniprot_id": "A0A8M1PHT1_DANRE", "id": "A0A8M1PHT1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MARPKVFFDLTAGGSPVGRVVMELRTDVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDGKHVVFGQVVEGLD-------VIKKVEGFGSSSG-KTSAKIIIADCGQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "id": "P14832-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "-----------------------------------------------------------------MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYD-------IVKKVESLGSPSG-ATKARIVVAKSGEL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LGT7-1", "uniprot_id": "A0ABK0LGT7_RAT", "id": "A0ABK0LGT7-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNPTVFFDITADGEPLGRVCFELFADEVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTCHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEDHHLRLWTTLISLTCGHFTHQTIPSVAQESTPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4J2A2-1", "uniprot_id": "PAL4C_HUMAN", "id": "A0A0B4J2A2-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4C", "aln": "---------------------------------------------------------------MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKERVN-------IVEAMEHFGYRNS-KTSKKITIADCGQF--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**: ....*:**: ::* * :*:****** *.**: *: * ** ***:**.** ****** ****.***** ** ***: :* .* *******.********* *. ***.***.**:* : . : . . . : .. ", "identical_positions": 77, "similar_positions": 36, "identity": "32.49%" }, { "cls_id": "homologset.agr.HGNC:33996", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "id": "P14832-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "-----------------------------------------------------------------MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPS-----------------GATK---ARIVVAKSGEL-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25007-1", "uniprot_id": "PPIA_DROME", "id": "P25007-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQS-----------------GKTS---KKIIVANSGSL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PHT1-1", "uniprot_id": "A0A8M1PHT1_DANRE", "id": "A0A8M1PHT1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MARPKVFFDLTAGGSPVGRVVMELRTDVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDGKHVVFGQVVEGLDVIKKVEGFGSSS-----------------GKTS---AKIIIADCGQL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LGT7-1", "uniprot_id": "A0ABK0LGT7_RAT", "id": "A0ABK0LGT7-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNPTVFFDITADGEPLGRVCFELFADEVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTCHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGK-------VKEDHHLRLWT--------------TLISLTCGHFTHQTIPSVAQESTPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCZ9-1", "uniprot_id": "M0RCZ9_RAT", "id": "M0RCZ9-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNLTMFFNITADGEPLGRVSLELFADKVPRTAENFRSLTTGEKGFGYKGSSFHRIIPGFMCQGGKVTCHNGTGGKSIYGEKFENDSFILKHTGPGILSMANAGPNTNGSQFFICTAKTERLDGKCVVFGKGRGGTNIVEAMEHFGSRNGKTSKKITISDCGQLLVSLICGHFTHQTIPSVAQESAPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DN37-1", "uniprot_id": "PAL4G_HUMAN", "id": "P0DN37-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4G", "aln": "---------------------------------------------------------------MVNSVIFFDITVDGKPLGRISIKQFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTHPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:: ....*:**: :: * :*:****** * **: *: * ** ***:**.** ***..* ****.***** ** ::.: :* .* *******.********* *. **.* *.**: :: . . . : :.. .. ", "identical_positions": 66, "similar_positions": 43, "identity": "25.58%" }, { "cls_id": "homologset.agr.HGNC:33997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25007-1", "uniprot_id": "PPIA_DROME", "id": "P25007-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLD-------VVKKIESYGSQSG-KTSKKIIVANSGSL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PHT1-1", "uniprot_id": "A0A8M1PHT1_DANRE", "id": "A0A8M1PHT1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MARPKVFFDLTAGGSPVGRVVMELRTDVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDGKHVVFGQVVEGLD-------VIKKVEGFGSSSG-KTSAKIIIADCGQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "id": "P14832-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "-----------------------------------------------------------------MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYD-------IVKKVESLGSPSG-ATKARIVVAKSGEL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LGT7-1", "uniprot_id": "A0ABK0LGT7_RAT", "id": "A0ABK0LGT7-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNPTVFFDITADGEPLGRVCFELFADEVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTCHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEDHHLRLWTTLISLTCGHFTHQTIPSVAQESTPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B759-1", "uniprot_id": "PAL4E_HUMAN", "id": "A0A075B759-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "aln": "---------------------------------------------------------------MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVN-------IVEAMEHFGYRNS-KTSKKITIADCGQF--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:*:: ...*:**: ::* * :*:****** *.**: *: * ** ***:**.** ****** ****.***** ** ***: :* .* *******.********* :. ***.***.**:* : . : . . . : .. ", "identical_positions": 75, "similar_positions": 37, "identity": "31.65%" }, { "cls_id": "homologset.agr.HGNC:33998", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25007-1", "uniprot_id": "PPIA_DROME", "id": "P25007-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLD-------VVKKIESYGSQSG-KTSKKIIVANSGSL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PHT1-1", "uniprot_id": "A0A8M1PHT1_DANRE", "id": "A0A8M1PHT1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MARPKVFFDLTAGGSPVGRVVMELRTDVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDGKHVVFGQVVEGLD-------VIKKVEGFGSSSG-KTSAKIIIADCGQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "id": "P14832-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "-----------------------------------------------------------------MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYD-------IVKKVESLGSPSG-ATKARIVVAKSGEL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LGT7-1", "uniprot_id": "A0ABK0LGT7_RAT", "id": "A0ABK0LGT7-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNPTVFFDITADGEPLGRVCFELFADEVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTCHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEDHHLRLWTTLISLTCGHFTHQTIPSVAQESTPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F5H284-1", "uniprot_id": "PAL4D_HUMAN", "id": "F5H284-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "aln": "---------------------------------------------------------------MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVN-------IVEATEHFGYRNS-KTSKKITIADCGQF--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:*:: ...*:**: ::* * :*:****** *.**: *: * ** ***:**.** ****** ****.***** ** ***: :* .* *******.********* :. ***.***.**:* : . : . . . : .. ", "identical_positions": 75, "similar_positions": 37, "identity": "31.65%" }, { "cls_id": "homologset.agr.HGNC:33999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25007-1", "uniprot_id": "PPIA_DROME", "id": "P25007-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLD-------VVKKIESYGSQSG-KTSKKIIVANSGSL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PHT1-1", "uniprot_id": "A0A8M1PHT1_DANRE", "id": "A0A8M1PHT1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MARPKVFFDLTAGGSPVGRVVMELRTDVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDGKHVVFGQVVEGLD-------VIKKVEGFGSSSG-KTSAKIIIADCGQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "id": "P14832-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "-----------------------------------------------------------------MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYD-------IVKKVESLGSPSG-ATKARIVVAKSGEL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LGT7-1", "uniprot_id": "A0ABK0LGT7_RAT", "id": "A0ABK0LGT7-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNPTVFFDITADGEPLGRVCFELFADEVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTCHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEDHHLRLWTTLISLTCGHFTHQTIPSVAQESTPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DN26-1", "uniprot_id": "PAL4F_HUMAN", "id": "P0DN26-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4F", "aln": "---------------------------------------------------------------MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVN-------IVEAMEHFGYRNS-KTSKKITIADCGQF--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:*:: ...*:**: ::* * :*:****** *.**: *: * ** ***:**.** ****** ****.***** ** ***: :* .* *******.********* :. ***.***.**:* : . : . . . : .. ", "identical_positions": 75, "similar_positions": 37, "identity": "31.65%" }, { "cls_id": "homologset.agr.HGNC:34", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78363-1", "uniprot_id": "ABCA4_HUMAN", "id": "P78363-1", "name": "Retinal-specific phospholipid-transporting ATPase ABCA4", "aln": "---MGFVRQIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSHHECHFPNKAMPSAG-MLPWLQGIFCNVNNPCFQSPTPGESPGIVSNYNNSILARVYRDFQELLMNAPESQHLGRIWTELHILSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVYLLINSQVRPEQFAHGVPDLALKDIACSEALLERFIIFSQRRGAKTVRYALCSLSQGTLQWIEDTLYANVDFFKLFRVLPTLLDSRSQGINLRSWGGILSDMSPRIQEFIHRPSMQDLLWVTRPLMQNGG-PETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYDRRTTSFCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARRILKNANSTFEELEHVRKLVKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGITAEAILNFLYK--GPRESQADDMANFDWRDIFNITDRTLRLVNQYLECLVLDKFESYNDETQLTQRALSLLEENMFWAGVVFPDMYPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYIWGGFAYLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDSFM--IILNRCFPIFMVLAWIYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGRILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQDRMTAELKKAVSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLSMQMMLLDAAVYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLG----GEGCSTREERALEKTEPLTEETED----PEHPEG-------------------------------------------IHDSFFEREHPGWVPGVCVKNLVKIFEPCGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFHHLTVAEHMLFYAQLKGKSQ-----EEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTCSCSSKG-FSTTCPAHVDDLTPEQVLDGDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGPLFAGGAQQKRENVNPRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPECPGPQLNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPALTLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRCLKEGWLP-EYPCGNSTP-WKTPSVSPNITQLFQKQKWTQVNPSPSCRCSTREKLTMLPECPEGAGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIPDFLKHLETEDNIKVWFNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITVISQPLNLTKEQLSEITVLTTSVDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSVSAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDVYARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTLLVQRHFFLSQWIAEP-------TKEPIVDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDELLTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQGNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQVFVNFAKQQT-ESHDLPLHPRAAGASRQAQD--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35600-1", "uniprot_id": "ABCA4_MOUSE", "id": "O35600-1", "name": "Retinal-specific phospholipid-transporting ATPase ABCA4", "aln": "---MGFLRQIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAG-LLPWLQGIFCNMNNPCFQNPTPGESPGTVSNYNNSILARVYRDFQELFMDTPEVQHLGQVWAELRTLSQFMDTLRTHPERFAGRGLQIRDILKDEEALTLFLMRNIGLSDSVAHLLVNSQVRVEQFAYGVPDLELTDIACSEALLQRFIIFSQRRGAQTVRDALCPLSQVTLQWIEDTLYADVDFFKLFHVLPTLLDSSSQGINLRFWGGILSDLSPRMQKFIHRPSVQDLLWVSRPLLQNGG-PETFTQLMSILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPAYSYDKRTTSFCNSLIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRIMKNANSTFEELDRVRKLVKAWEEVGPQIWYFFEKSTQMTVIRDTLQHPTVKDFINRQLGEEGITTEAVLNFFSN--GPQEKQADDMTSFDWRDIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRALSLLEENRFWAGVVFPGMYPWASSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYIWGGFAYLQDMVEQGIVKSQMQAEPPIGVYLQQMPYPCFVDDSFM--IILNRCFPIFMVLAWIYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMALSIFLLTLFIMHGRILHYSDPFILFLFLLAFATATIMQSFLLSTLFSKASLAAACSGVIYFTLYLPHVLCFAWQDRMTADLKTTVSLLSSVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLG----GEGCSTREERALEKTEPLTEEMED----PEHPEG-------------------------------------------MNDSFFERELPGLVPGVCVKNLVKVFEPSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETNLDVVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSW-----EEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVCSCTSKG-FSTRCPTRVDEITEEQVLDGDVQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGSMFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQ-VDPPKGQPSPEPEDPGVPFNTGARLILQHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPALTLHPWMYGHQYTFFSMDEPNNEHLEVLADVLLNRPGFGNRCLKEEWLP-EYPCINATS-WKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLPPPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPAIPISGEALVGFLSGLGQMMNVSGGPVTREASKEMLDFLKHLETTDNIKVWFNNKGWHALVSFLNVAHNAILRASLPRDRDPEEYGITVISQPLNLTKEQLSDITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSCANLFIGINSSAITFVLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTLLIQHHFFLTRWIAEP-------AREPVFDEDDDVAEERQRVMSGGNKTDILKLNELTKVYSGSSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTSISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPSKEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALTGCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQGNFPGSVQRERHHSMLQFQVPSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQT-ETYDLPLHPRAAGASWQAKLEEKSGRLQTQEPLPAGSEQLANGSNPTAAEDKHTRSPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R045-1", "uniprot_id": "F1R045_DANRE", "id": "F1R045-1", "name": "P-type phospholipid transporter", "aln": "---MSTGRQIRLLLWKNWTLRKRQKIRFFVEILWPVFLFIGLVWLRRANPLYRQHECHFPSKAMPSAG-ILPWIQGIFCNANNPCFRHQTRGESPGVVSNYHNSILARFYLDSQELLFNDTEFLQLGRLWREASIMSNFMETLRTSPERVAGKGLKVEDILKDDETLTAFLLRDARLSEGVVHDLTNAQIRVEQFAYGVPDLTLKEIACSQALLEQFLIFPSRGGMYGVQNAMCALSQHRLQRIEDVLYANIDFFKLFRLMPMVLDSHSTGIDLQFWGRVLSAVSDKLQELADRPSAQDLMQVLYSIFQPGG-PSSFSQLISKVSDLFCGYPEGEGTRVFSFNWYEDNNYKAFLGINNSRGHDSYIYDKTATPFCNALMQNLESNPITKIVWNSVKPLVMGKILYTPDSPAVRKIIKSANTTFEELERLQKIGKVWEELGPQLWDFFQNSIQMNMIRDTLRNPTVMDFLDRRLRETEFSTKDILNFLHN--GPEGERFMNMTSFDWSDVFRLADQAIRMFNRYSECISLDKFVGHMDENLMTHQALHLLGENKFWAGLVFMDMYPWTIELPRHVKFKIRMDIDAVERTNKIKDRYWDPGPRADPVEDHRYIWGGFAYLQDLIEHGILKLHTGHDWPLGVYLQQMPYPCYVDDMFM--LTLNRCFPIFMVLAWIYSVSMVVKSIVLEKEMRLKETLKAMGVSNGVIWYTWFIDSFIMMTASTALLTGIVMAGKVLNYSNPIILFLFLLTFTVATIMQCFLMSVFFNKANLAAACSGIIYFTLYLPHIFCFAWQDRITKDMKLAVSLLSPVAFGFGTEYLSRYEEQGLGLQWDNIGTSPLEGDEYSFFTSIRMMLLDAVLYGVLAWYLDNVFPGQYGIGRPFYFPLQSSYWLKPSPPSETSNAVPEKPLENHVEKQEDVEYGGLSPEHRECNGSRNSKHCKHKEKRERMEKEREREEQLKMQEEIQQEEIQQWYCENPFFEPEPESLLIGVSVQDLVKMYNRYSRPAVDCLNMNFYESQITSFLGHNGAGKTTTLSILTGLFPPTSGTAYIYGRDIRTEMDAIRQSLGMCPQHNILFKHLTVEEHILFYSLMKGREH-----KEAEQEVENMLEDLGLPHKRDEEAQNLSGGMQRKLSVAMAFVGGSRVVILDEPTSGVDPYSRRSIWDLLLKYRTGRTVILSTHHMDEADLLSDRVAIISKGKLHCSGSPLFLKNCFGVGFYLTLVRRMKDQRKKENECDCASECSCTCSTCTRYKEESQALQPERVLDGNVESITTLIHHHVPEAKLIEMIGQEMTYLLPNKGFKYRAYASLFRELEETLGDMGLSSFGISDTSLEEIFLKVTADGEAANSSVTPEQWMLQQRKNGNGFMKDTG----LAEDANGVGASLESDSSEGRASRQVK--------GFSLVLKQFHALLVKRFHHATRSHKDFLAQIVLPASFVLIALVFTMIVPPFGEYPCLTLTPWMYGPQFTFISNEQPSHPKMKHFIQTLLKDPGMGTRCMANQPLENIFTCLNSSSDWEVPPVSPEVSNILSSPEWDSRNPSPSCECSTDLKLTMLPMCPAGAGGLPPRQRKEPTGDILLDMTNRNISDYLVKTYTKLIKTSLKSKYWVNEQRYGGISVGGRLPILDVDPEEIQNIFSQLGRMMNIRGGRYSKSAMDELETFLHYMESEYNVKVWYNNKGWHAMASFLNVANNAILRAYLPPHANPSDYGITAINHPLNLTKEQLSEVTVLTTSVDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPLVYWFANFFWDMLNYSVSTAMVVAIFVGFDKKCYTSPTNLPALIALLCLYGWSVTPMMYPLSYMFNVPSTAYVSLSCINLFIGINSSAITFILELFENNRSLLMFNEVLKKVLLVFPHFCLGRGLIDMAMNQAVTDVYARFGEEFSMDPFRWNFVGKNLFCMAVEGFVYFIFNLLIQYKFFLHHWISDY-------GMSLGTDEDDDVAQERERIYKGGNKNDILLIRDLSKTYRRRKRPAVDKICVGVPAGECFGLLGVNGAGKTTTFKMLTGDTDVTSGELSVAGYSILSNILDVHQNMGYCPQFDAIDELLTGREHLYLYARLRGIPESEISRVAEWGIQKLGLSEYAGNCAGTYSGGNKRKLSTAIAMIGCPPLVLLDEPTTGMDPHSRRFLWTAILSIIRDGRAVVLTSHSMEECEALCTRLAIMVNGTFKCLGTIQHLKYKFGGGYVVTMKIKAAKPGLSPDLVPAESFMDSSFPGCIQREKHYNTLQYEIAAASLARVFQLVLTNKERLNIEDYSVSQTTLDQVFVNFAKQQSGEDDTAPSHLRQSGPKREKKVSPLQRVATKNR---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JG15-1", "uniprot_id": "X2JG15_DROME", "id": "X2JG15-1", "name": "", "aln": "MRVHLNGREVRELLRKDLLVRWRQKGLSLILLAWPVMVFMLLYLIRLKYGSEELEACQYPTRLLPTKNQVVPAAFSYICSIENRCQPAHPYEEYS----HWKEAPLHSVIDVVNAFVTDERLHKAVVELAEKANFVSAITTLITSDR----------FDIIRSNISEIISLVPEIERRMNYSFDIKHLFSNRETFVKLGVLLCGHPFPNTDTIPLVNEILESEDFSQANDAEIDAMPTRRRRRYEDLP---TDWRPTKYCKRLYRDVTSTNQGKLTWNTIKPIIQGRILYTPANAMTESVVKFSNASFEELDRLKQLSRAAATILTKLHTNATFQEAFDNLLKLAKSPLVKSLVGDDFDIGEIERVFEYIRTNQLIYDILTTVADLMDCVSADRFEAVESVEELHKRAYELNQNKLFLAALNLEDVGLKQASYRLHMDT-DNTQPTFENRNRFWFPGPADSMVIDLKYHRGFVQLKQMVDLGIIKSKREEAGFAPEEDGPESGRSLSGLFSIKQVENDTPDEDDDDFDLSLEESGDEKAAPKVSASASDHEATTIS--------PSSLDGVTTEEVRVTTEQTVVSGDPDLLLLKNEDVLKRSKRQGLFDLLGGFGGSGDANKKNKFEVDN-----MQFYTKQFPYPAFLNDVFKRGLYLAQGVQVAYLLGLVVFVALSVRERIWMRESRNSMLMRSMGLKAHSELVAWALMSFLELCVIFALISGVLYSGGILGYTNWFFMMFYCLSFGLCLISFCYMCTNFFNSANIGAVASALLFFISLCPFIIVLMFDAKLSVFESFLVDLSFTTAFAKGWGELIRMELQQEGLTVRHLIQVGPARS--ECAMALLMFLLDLLLYAVIGLAYQRYKKTDN-----YSFVKVSRSQLDG---------------------------------------------------------------------------------------------KLGASLVNVSKLYG--SKCAVSNLSLDFARNQVSCLLGRNGAGKSTLIKLLTGQIRQSSGKVLLAG----------EHQVGVCWQDNILIPTLTAREHLQLYAQIKIPPGGSGGVEEIRSEVAQTLQSLNFGKHESYPSWQLSGGYRRRLCVAIAFIASPSVVILDEPCNGVDAKARKDIWQLIERLRQGRAVIFATHFMDEAKYLSDSLVIMRNGRIIAQHSRDSLQRLCTSNYSIRLR------------------CADATGVTFVIQKAQQLLPQTQVTHSGAADYPHSLTINASYAEHLTPGAVEFLELLQS------------QVTAGSISDVELTTS----SSLEQEFEQLNRNGEDAGPRRPASD-----------------------RSGVVAGPAMITDEP-------------------PTACKQFRLLMGKRLRHLSRNYRLLLYVLLLPALFELCAMWFVSYRLEDDFDTVLPLSRSLYPQTAQFLSHER-----------------------------------------------ATSFSEKLYPQLRTSCDHLGECRVFN---------------------------------TSQQSYDWVLNSWGEYS-----------ERRYGGYGLNG------------------------------------------------SGATVWYNNKGYHSMMAWLNDLNSELLRTTMND----SESSILTLNEPWKLGFAELSTSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIFCANLIVPLVTMGIILILGVVGDGPAWDDWRHALNQAFLIFPIHALGDGFLELCKNYMVALVFRRYDIDSYKHPLASDLLGRHFTALLLVGVAALIINVLIEWHLLRRLWQRVERLLDCTYRRELDKLGQLKLVNIQSIFKSCVDTGEAVRAENLWLAYRRG-HYAVRNVNFSVQRGECFGLLGKNGAGKSTIFKLLTGQLQPDVGQIYFE-----------QPGISYCPQSNPLDPLLTTTECIRFYGRLRGIR--DLDQFLDRVLDTYELRPYKDVQVRNLSGGNRRKLTVAVTCCGCTPTVLMDEPTSDMDPVTRDMVYATIEQLLLARRAVVLTSHSVSEIEHLCQRVAVLRAGQVIASDSPQRLKSEHGGYYAVTCFCGPAQQAILSRS------LNQRLPGARDLQHYAHSLRFLVRVRSPGSLGDAPLLSELFAILCDVCVNVARFSLSRCRFETVFERILDSSESNGSNGVHKDQQQQVAKNDLPSKSPAVGGTLETGYIHCGYEETRT-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5PQJ5-1", "uniprot_id": "RHG29_RAT", "id": "Q5PQJ5-1", "name": "Rho GTPase-activating protein 29", "aln": "-------------------------------------------------------------------------------------------------------------------MIAHKQKKAKKKRVWASGQLSAAITT----------------------------------------------------------SEMGLKSVSSNSIFDPEYIKELVNDIRKFSHVLLYLKEAILSDCFKEVIHIRLDELLHMSKHQNLNSVDLQNAAETLASKVKAVNFTEVNDENKNDLFREVFSSIETLAFTFG-------------NILTNFLMGDVGNDSILRLPISRESKSFENISMDSVDLPHEKGNFSPIELDNLLLKNSDSIELALSYAKTWSKYTKNIVSWVEKKLN-----------LELESTRNIVKLAEATRSSIG-----IQEFMPLQSLFTNALLNDIHSSHLLQQTIAALQANKFVQP--LLGRKNEMEKQRKEIKELWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSS-------VGLGKNLNKLLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRND-------------------------------------------------LENTKREILTQLRTLVFQCDLTLKAVTVN-------------------------------------------------------------LFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKATSSSELEEKVDGNVNKQIASSPQTSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YEPADSLEDVARLPDSCHKLEEDRCSN-----------SADMTGPSFIRSWKFGMFSDS------------------ESTGGSSESRSLDSESISPGDFHRKLPRTPS---------SGTMSSADDLDER-EPPSPSEAGPNSLGTFKKTLMSKAALT--HKFRKLRSPTKCRDCEG---------------IVMFPGVECEECLLVCHRKCLENLVIVCGHQKLQGKMHIFGAEF-------------------------------------------IQVAKKEPDGIPFVLKICASEIESRALCLQGIYRVCGN-------------------------------KIKTEKLCQALENG--------------------------------------------------------------------------MHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAK-------------------------------------------------------------------------EIQHVNEEQEAKKDSPED------------------------------------------------------------------------------------------------------------------------------------KKHPHVSIEINRILLRSKDLLRQLPASNFNSLHYLIVHLKRVVDHAEENKMNSKNLGVIFGPTLIRPRPTTAPVTISSLAEYSSQARV------------------------------------VEFLITYAQKIFDGSLQPQAGVIAN--------------------------------------TGAIAPQVDHGCHPKPLLSPDERDSDHSLKQLFFSSKEDIRTMDCESKTFELTTSFEESERKQ----NALGKCDAPILDN---------------------------------KVHLLFDQELESASHKTEDTCKSPKLLLLRSDRVANSVQRPTPRTRLRPVSLPVDRLLLLAGSPTERSSRN---TGNTDSDK-----------------------FGKNAAFEGLHRKDNSNTTCSKVNGFDQQNVQKSWDKQNERNSFTAKTTVIIPSAYAEKGLAVSTGNNRGHSSGAAQPSKAHADPARSAR--------------------DTSEHSSSDSCPVAAVRAPRTLQPQHWTTFYKPPNPTFNVRGTEEKTAFP------------SAAVPPVLVHAPQSHVAKSDPDLEATLACPVQTSGQPKESSEEPGLPEGTPTCQRPRLKRMQQFEDLEDEIPQFV-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . .: . : : : .. .. : . : :: * . . . : . .: . ..:. . . : :. . *:: . . . . : . . : . : : :: : : . .: . : : : .. . :: : : . * : . * : . : : : .:. . . . .. : : : : : : :: * : . : . : . .. . . : : :: . : .: . .: :: :: : . . . : :* : . * : : . * . . .: :: :. . . . *:. . . : * :: * *: . * .* . * . :::. :*. : . : : . . :* . : .. : : : . . : : : :. .: : ..: : ** * : : .. . :: : . :** . * :.. . : . * . : : . :* * : ** : .:: : : . : . : : .* : . . . : .. .: : . . : : . . : :*: : . : .: . .. . : .. . .: : : **. . : ::: **: : .:: * : .::.*. ::.: : . : . . : ::.. .. .:. :. :* . * . . * *: . * .. * . : : . : : . . . ", "identical_positions": 42, "similar_positions": 310, "identity": "1.76%" }, { "cls_id": "homologset.agr.HGNC:34000", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2F9-1", "uniprot_id": "A0A0G2K2F9_RAT", "id": "A0A0G2K2F9-1", "name": "", "aln": "------------------------------MSFPLTPNLPFRPPCHNRDFQTLPLPPWICLTSLPLSAGAGGQRNQLREASMENGERKKLTSTLS-DGDHKEENKLKQGIPQDLSSSPKL-------DRYKIARQLTEKAIKEKKIFSIYGHYPVIRATLRRKGWVEKKFN---FFPKPLQNVEGE------DKSAETKENQEIALER-FDDIHDVMSRLVKNEIPYLLWTIKRDVVDYHSLTCDQ-MLNHYGKTASFTTKIGLCLNMRSLPWYVQAN-PNTFFPRCYGLCTE--SEKQEFLDDFRRTVAASILKWVVHHQNY--CNRAKGKSKKEEAKNGDPSPKKDPDNPDLKLPSLSGQVVDTACKVCQAYLGQLEHEDIDLSDASAEALSEE-EWNDLTQQYYLLVHGNASITDS-----RSYFAQCQALLSKISSVNPQTEIDGIRNIWIIKPAAKSRGRDIVCMDRVENILDLVATDSQTTKDNKWVVQKYIETPMLIYDTKFDIRQWFLVTDWN-PLTIWFYKESYLRFSTQRFSLDKLDSAIHLCNNSIQRRLKNDKERSPLLPCHNMWTSTRFQEYLQKRGRGGTWGSIIYPSMKRAVTNAMRVAQDHVEARKNSFELYGADFILGRDFKPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVVVDRKLDRNCDIGNFELLWRQPAVELPPFNGSDLCVEG-----------------ISVKKAKKQMPPIANLGFSDSLLDA-PTKARSARPLPET---------VIGPSRMTVRPDWKREEAKVLSNTWSAPVMAAEVRG--------QAKPTYAFDVNNYQHVDSKAYKSTFTKVQSGKHSEVNLISAQYPALVLQNMQRTQ---SPPPR----------------------ASGSRRDSMP----FCPIVFEELWLHPSSQRRP------------------------SSCILQNRAQGWIRGIP-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4Q9F1-1", "uniprot_id": "TTLL8_MOUSE", "id": "A4Q9F1-1", "name": "Protein monoglycylase TTLL8", "aln": "------------------------------MSCPPTPNPPFRPPSHTRVLRTPPLPPWVCLNSKSLSTGVGGQKNQLREASMENGERKKLSSTLS-DGDHKEENKLKQGIPQDLSSSPKL-------DRYKIARQLTEKAIKERKIFSIYGHYPVIRATLRRKGWVEKKFN---FFPKALQNLGSE------DKSAETKENQEIALER-FDDIHDVMSRLVKNEIPYLLWTIKRDVVDYHSLTCDQ-MLNHYGKTASFTTKIGLCLNMRSLPWYVQAN-PNTFFPRCYGLCTE--SEKQEFLDDFRRTVAASILKWVVLHQNY--CSKVKGKSKKEEAKNSDPSPKKDPENPDLKLPSLSGQVVDTACKVCQAYLGQLEHEDIDVSEASTEALSEE-EWNDLTQQYYLLVHGNASITDS-----KSYFAQCQALLSKISSVNPQTEIDGIRNIWIIKPAAKSRGRDIVCMDRVENILSLVAADSQTTKDNKWVVQKYIETPMLIYDTKFDIRQWFLVTDWN-PLTIWFYKESYLRFSTQRFSLDKLDSAIHLCNNSIQRRLKNDKERSPLLPCHNMWTSTRFQEYLQKRGRGGTWGSIIYPSMKRAVTNAMRVAQDHVEARKNSFELYGADFILGRDFKPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVVVDRKLDRNCDIGNFELLWRQPAVELPPFNGSDLCVEG-----------------ISVKKAKKQMPPIASVGLSESLLDA-PPKVRSARALMET---------VIRPPRTTVRQDWKREEAKVLSTTWSMPVMDAEVRG--------RAKPIYAFEVNDYQHVDNKSHKSGYTRVQSSKVPGVTLTSAQHPALFAQTMKPTQMTSSPPPT----------------------ASGNHRDSSP----FCPIVFEELWLHPNSQRRP------------------------SSCILQSRAQGWIRGIP-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6PVC2-1", "uniprot_id": "TTLL8_HUMAN", "id": "A6PVC2-1", "name": "Protein monoglycylase TTLL8", "aln": "---------------------------------------------------------------------------------MEP-ERKGLSLASSSDGDGREENKLKQGISQDLASSSRL-------DRYKIARQLTEKAIKEKKIFSIYGHYPVVRAALRRKGWVEKKFH---FLPKVIPDVEDEGARVNDDTCAKVKENQEMALEK-TDNIHDVMSRLVKNEMPYLLWTIKRDIIDYHSLTYDQ-MLNHYAKTASFTTKIGLCVNMRSLPWYVPAN-PDSFFPRCYSLCTE--SEQQEFLEDFRRTMASSILKWVVSHQSCSRSSRSKPRDQREEAGSSDLSSRQDAENAEAKLRGLPGQLVDIACKVCQAYLGQLEHEDIDTSADAVEDLTEA-EWEDLTQQYYSLVHGDAFISNS-----RNYFSQCQALLNRITSVNPQTDIDGLRNIWIIKPAAKSRGRDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIETPLLICDTKFDIRQWFLVTDWN-PLTIWFYKESYLRFSTQRFSLDKLDSAIHLCNNAVQKYLKNDVGRSPLLPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPRKNSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVAVDR----SCDIGNFELLWRQPVVEPPPFSGSDLCVAG-----------------VSVRRARRQVLPVCNLKASASLLDAQPLKARGPSAMPDP---------AQGPPSPALQRDLGLKEEKGLPLALLAPLRGAAESGGAAQPTRTKAAGKVELPACPCRHVDSQAPNTGVPVAQPAKSWDPNQLNAHPLEPVLRGLKTAEGALRPPPGGKGEGTVCSRLPHHGHHVAACQTTGTTWDGGPGVCFLRQLLASELPMGPGLPRDPRAPPCLVCRGLLPPAGPCKRCRSFCAAVLQGASFVRLGGRSCSPRTP-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1ECV4-1", "uniprot_id": "TTLL3_DANRE", "id": "Q1ECV4-1", "name": "Tubulin monoglycylase TTLL3", "aln": "--------------------------------------------------------------------------------------MHQHIQVPPLEGKSR-----INYVNLPLING----------DKLRTAKTLVDKAIKEKKVFSVQGPYPVIRAGLRARGWVERRLPRPSFSQPRRHDHETETTD-EGDSSDEDDLGEEVERDDEAEDLYDLMSRLVRHETPYFYWTTRRDSVDCRSLRKEQ-MTNHYAKAGSFTTKVGLCMHLRNLQWFDAAD-PDTFFPRCYRLGAQ--DEKHAFIDDFRRTACTSLLLYVLEKYEG--DSEGEKMGEVHNAKSHGLRKTRKQHSS----QRIETSVIDSALHVCQEYLNSLEHCDIDNNLETNSTISEQ-QWKVFLQNYYLVVHEGINIEGC-----EYYLERCKCMLEQMRQVCPQMENDGICNIWIIKPGAKSRGRGIMCMNKLDDMLGLVDGDHCIMKDSKWVVQKYIERPLLVHDTKFDVRQWFLVTDWN-PLTVWFYRECYLRFSTQPYSTHTLDSSVHLCNNSIQKHYQPSPDRSPSLPAECMWSCSQFRSWLAASGRAALWKAVVVPGMQKAVIQTLLTAQDSVEPRKASFELYGADFMLGRDLRPWLLEINASPTMAPSTGVTARLCPAVQEDTLRVVLDRRSERNTDTGGFQLIYKQAAVDVPQYVGVNLLIEG-----------------TSIRRPRAPVHKSLIQSHPEPLSKSTNHKSSLLSSPCTS---------GKENQSEEVKRACPNLPNRKITMDQSLIFHPKRKRP---------HRLVLPSTCCVLPNPTELHHPQRLSHTQPQSDRPHTHRTRSNLPTLYRPTPSVEVINIRPRQ--------------------ALTSSHYIHKIH----TVNLSYPVLRMQQNHRRSK-------------------------------NTFAEREGPKSS-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM91-1", "uniprot_id": "TTL3A_DROME", "id": "Q9VM91-1", "name": "Tubulin glycylase 3A", "aln": "--MQTRPSSEPHRSRDQVTDGDRNRDQPQKCASATLAKKPVTPPAAPPPTPSNRVVAPLTVPVIQLTPAQSDSPVKLARPATPKETAISVPDHSNKENQPARTPPPSKSCPLGAPTNYVARRTWITTERMNELRRKAQEAAKQNKIFTIRGCFNSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCER------NIMSRFLEHMPVDFLWTNRKEKCDYIDQAKNPGMTINKFHRAPFTSKEGLCSQLRDFHWFFEEGTAEMYFPRCYNVWSP--EELGEFIENFKLTACVAFLRAMLCKYHK------QGSDAVFSCSG-----------------KIPYSAIDFAYKRLVEYIDSCQHNDIDFEDP--PKIWEH-DWDAFLFQHQQLVNEDGRIQHDGGQRLEPMVKSCLSLVDKMKVHWPQYSLDGYQNMWIVKPANKCRGRGIILMDNLKKILGVVN--LSIASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQ-PLVVWFYRESYLRFSSQEYSLSNHHESVHLTNYAIQKKYTNGK-RDKRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGCMLASQENMDRRPNTFELFGADFMICENFYPWLIEINSSPDLGATTSVTARMCPQCLEDVVKVVIDRRTDPKAELGNFELAYRQVVPPTPAYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIHRAMPTFNATEYMEKYMVEPLSSSRSSLCSQLPQKSPSAAPALTATPSGATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQVQSTALPPKRQRSCGPRLSSTNPVESTEKKFKILIKNYSSNGNEN-------MQDARPEVANSATATAISERKWRSLRNIAATAGGSSNLAARSKGPPLIAPPSLPTRRLTRTKSEIDSTGMHAIGRTFGRKSNGPRLPISISVQALHRGEPIVAALKQATSELQLSQAQMMSPRTALANKLNGSTLMVPASALPVG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM92-1", "uniprot_id": "TTL3B_DROME", "id": "Q9VM92-1", "name": "Tubulin glycylase 3B", "aln": "MTTQNTTPAGFTGNRNRYYNPVSKIQSLIHNLDAELVQLCKQCSVQKPLTSLNNSTSLGSHFSNFGALGGGSGSKTMGGSSSMGSNNFSPDSIGNLLARVRASTPLPRTVTSSPTAPEAQKR-----QMRNVYRTRVIDAYRNRRIFTVYGNYHTVRRALMRRGWLEKLPASR-----------------HAKLQSMSEDALLEHARRGNDYEAVVISKMINHFPAFFIWQGKGQRDLCAEVRPFR-NRVRRSQFLDFSTKVGLVGCAEQERWYREDGVCGMSYPRFYRLGGNNLEERMAFIEDYQQTQARSLLLYVREHQPA----------ELISENG-----------------TIFSTTLDFALGKVKKMVRHAEHYSLDDARIKPPTPAEIVENQTFMVQSTDVLKSNAKFKVS-EKVMAEYARLAGLYLDQIESLRPDYRWDGSRNLWILKPGYQSRGIGIVIRSSLDDILQWTS----NNQNKKYIVQKYIERPLLIYRTKFDIRQYMLLTITDTKVSIWTYRDCYLRFSSQEFTMDDLRESIHLTNNSVQKRYKNKTNRDSRLPKNNMWSLDQFKNYLRIMGAPDGSWSKTYNGFKQNLVAVVMASLDETELLQNAFELYGCDFMLDEHYNPILIEINSTPDLSPSTEITARICPMVLKDCIRVVVDLPKNPTAATGLFELAFEVNYSINKGADGKPLELNG---------------------KQMTLFENMPRMRNS--------PRTRLLRKILNN----------VKTSTTKKVEKVVEAPAKN-----------------------------VKNPTAKITKKKKLSASAGSSTAASAQPSTQNLTTKLILNPATRENLALQYTAPK----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . .* ::.::*:: * : :* * :**:*: ::*:::.: : * : : . . : *::* ** .. *: . :** * : .* *::::: * . ::* : : . . : :* * : :* .:* * : . : : ::: . : . :.:: *: ** *:**:**. :.** .*: . :..:* . ..:::****** *::: ****:**::*:* : : :* *::.*****:* :: .::** * ::*: *. ** . ** *: :* * .::: : : .: : : :***:*.**:: .. * *:***::* : .:* :**::*. :* ::*.:* . * *:* :. * * : * : . : . . . . . : ", "identical_positions": 99, "similar_positions": 163, "identity": "9.53%" }, { "cls_id": "homologset.agr.HGNC:34004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3Z9-1", "uniprot_id": "PO121_MOUSE", "id": "Q8K3Z9-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGGREGRSRARGYGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRALSSFVRDARRHPRPALTASPPPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALRQDPRERPGRRPPARSPPPASAVQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSPRNSRMVCSPVTVRIAPPDSKLFRSSMSEQILDTTLSSPSSNAPDPCAKETVLNALKEKKKRTVAEEDQLHLDGQENKRRRHDSGGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLASACTGGIPSSSRNAITSSYSSTRGISQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCQQSSSSPPLVTDKESPGEKVTDTTTGKQQSSWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERKASLQWFNKVLEDKPDDASASATDGPPSTSPPFTFTLPAVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPAEAATVAAPSPPKTPSLLAPLVSPLAGP---LASTSSDSKPAATFLGLASASSITPLTDSKSSGVSQAEQSVSTPASTASSPTPKPSMLFGMLSPPASSSSLATPAPACASPMFKPIFPATPKSESDSPLPSSSSAATTASSSTAPPTAASTTP-TFKPIFDKMEPFTAMPLSTPFSLKQTTATATTTATSAPLFTGLGTATSTVASGTAAS-----ASKPVFGFGVTTAAS----TASSTMTSTSQSVLFGGAPPVTTSSSAPALASIFQFGKPLAPAASAAGTSFSQPLASSTQTAASNS--GFSGFGSTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSSSAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAP----------------ATFGSAAQPAFGGLKAAASTFGAPASTQPAFGSTTSVFSFGSATTSGFGAAATAATTTQTTNSGSSSSLFGSSAPSPFTFGGSAAPAGSGGFGLS-ATPGTSSTSGTFSFGSGQSGTPGTTTSFG-SLSQNTLGAPSQGSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGASSTPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52591-1", "uniprot_id": "PO121_RAT", "id": "P52591-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRGLSSFVRESRRHPRPALTASPLPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALPQDPRDRPGRRPPSRSPPSSSTAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLFRSPMPEQILSTTLSSPSSNAPDPCAKETVLNALKEKKKRTVAEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTSTCTGGIPSSSRNAITSSYSSTRGVSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCHQSSSSAPLVTDKESPGEKVTDPATGKQQSLWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERRASLQWFNKVLEDKTDDASTPATDTSPATSPPFTLTLPTVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPPEAATVAAPSPPKTPSLLAPLVSPLTGP---LASTSSDSKPTTTFLGLASASSATPLTDTKAPGVSQAQLCVSTPAATAPSPTP-ASTLFGMLSPPASSSSLATPGPACASPMFKPIFPATPKSESDNPLPTSSSAATTTPASTALPTTATATAHTFKPIFESVEPFAAMPLSPPFSLKQTTAPATTAATSAPLLTGLGTATSTVATGTTAS-----ASKPVFGFGVTTAAS----TAS-TIASTSQSILFGGAPPVTASSSAPALASIFQFGKPLAPAASVAGTSFSQSLASSAQTAASNSSGGFSGFGGTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSASAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAP----------------AAFGGAAQPAFGGLKASASTFGTPASTQPAFGSTTSVFSFGSATTSGFGAAA---ATTQTTHSGSSSSLFGSSTPSPFTFGGSAAPAGGGGFGLS-ATPGTGSTSGTFSFGSGQSGTTGTTTSFGGSLSQNTLGAPSQSSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGAPSTPAQGFVGVGPFGSGAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NF01-1", "uniprot_id": "P121B_HUMAN", "id": "A6NF01-1", "name": "Putative nuclear envelope pore membrane protein POM 121B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRVRTS--------------------------------ELWKRNGPSSSPFSSPASSRSQTPERPAKKIREEEMCHHSSSSTPLAADKESQGEKAADTTPRKKQN-SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLAT--SAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTLGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* *** :****.**:********************* **** *::****.**.:**** ***.:*.:. *:*. .* .***********:********:********:***********:*::*******:.****.* ** ..*: .* *.*.**:***:..**:.*:** ***:*********** .* *...*.. ***. * ******.**.** . :** *.*.* **:*.:*:*** .*.* .* **:*:. . **: ... *::*.**:* * *** . :*.** *:*..:.*********.*.****.:.* *...*.::*:.:*:: **::::*. **:*:*..: * :::**..** :****:.**:.:*:***:***.:***:**. *:** ****.****:.:.:* *:: * :::**..*** ** .:::* :**:.******** * .::.: *:***.*.::. **:*.* .*****.**:* *****:********** ********.:***..**:*****.**:***::* *:****:************.*.*.:.:*** .:**.*::.*** ***:**:**:***:*****.:*:*****:**:*****:: **: ******:***::**************.*.**:. ****:.:*:*:****:****:..*:*.*. .*.**:**:..*.:****.****.*********:***** .:*******:********.*:********.****.************ ****************", "identical_positions": 508, "similar_positions": 236, "identity": "41.03%" }, { "cls_id": "homologset.agr.HGNC:34005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3Z9-1", "uniprot_id": "PO121_MOUSE", "id": "Q8K3Z9-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGGREGRSRARGYGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRALSSFVRDARRHPRPALTASPPPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALR---QDPRERPGRRPPA----RSPPPASAVQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSPRNSRMVCSPVTVRIAPPDSKLFRSSMSEQILDTTLSSPSSNAPDPCAKETVLNALKEKKK-RTVAEEDQLHLDGQENKRRRHDSGGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLASACTGGIPSSSRNAITSSYSSTRGISQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCQQSSSSPPLVTDKESPGEKVTDTTTGKQQSSWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERKASLQWFNKVLEDKPDDASASATDGPPSTSPPFTFTLPAVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPAEAATVAAPSPPKTPSLLAPLVSPLAGP---LASTSSDSKPAATFLGLASASSITPLTDSKSSGVSQAEQSVSTPASTASSPTPKPSMLFGMLSPPASSSSLATPAPACASPMFKPIFPATPKSESDSPLPSSSSAATTASSSTAPPTAASTTP-TFKPIFDKMEPFTAMPLSTPFSLKQTTATATTTATSAPLFTGLGTATSTVASGTAAS-----ASKPVFGFGVTTAAS----TASSTMTSTSQSVLFGGAPPVTTSSSAPALASIFQFGKPLAPAASAAGTSFSQPLASSTQTAASNS--GFSGFGSTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSSSAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAPA------------------TFGSAAQPAFGGLKAAASTFGAPASTQPAFGSTTSVFSFGSATTSGFGAAATAATTTQTTNSGSSSSLFGSSAPSPFTFGGSAAPAGSGGFGLS-ATPGTSSTSGTFSFGSGQSGTPGTTTSFG-SLSQNTLGAPSQGSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGASSTPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52591-1", "uniprot_id": "PO121_RAT", "id": "P52591-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRGLSSFVRESRRHPRPALTASPLPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALP---QDPRDRPGRRPPS----RSPPSSSTAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLFRSPMPEQILSTTLSSPSSNAPDPCAKETVLNALKEKKK-RTVAEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTSTCTGGIPSSSRNAITSSYSSTRGVSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCHQSSSSAPLVTDKESPGEKVTDPATGKQQSLWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERRASLQWFNKVLEDKTDDASTPATDTSPATSPPFTLTLPTVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPPEAATVAAPSPPKTPSLLAPLVSPLTGP---LASTSSDSKPTTTFLGLASASSATPLTDTKAPGVSQAQLCVSTPAATAPSPTP-ASTLFGMLSPPASSSSLATPGPACASPMFKPIFPATPKSESDNPLPTSSSAATTTPASTALPTTATATAHTFKPIFESVEPFAAMPLSPPFSLKQTTAPATTAATSAPLLTGLGTATSTVATGTTAS-----ASKPVFGFGVTTAAS----TAS-TIASTSQSILFGGAPPVTASSSAPALASIFQFGKPLAPAASVAGTSFSQSLASSAQTAASNSSGGFSGFGGTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSASAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAPA------------------AFGGAAQPAFGGLKASASTFGTPASTQPAFGSTTSVFSFGSATTSGFGAAA---ATTQTTHSGSSSSLFGSSTPSPFTFGGSAAPAGGGGFGLS-ATPGTGSTSGTFSFGSGQSGTTGTTTSFGGSLSQNTLGAPSQSSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGAPSTPAQGFVGVGPFGSGAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8CG34-1", "uniprot_id": "P121C_HUMAN", "id": "A8CG34-1", "name": "Nuclear envelope pore membrane protein POM 121C", "aln": "MSPAAAAAGAGERRRPIASVRDGRG--RGCGGPAGAALLGLSLVGLLLYLVPAAAALAWLAVGTTAAWWGLSREPRGSRPLSSFVQKAR--HRRTLFASP-PAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAPAPEGQDLRNRPGRRPPARPAPRSTPPSQPTHRVHHFYPSLPTPLLRPSGRPSPRDRGTLPDRFVITPRRRYPIHQTQYSCPGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQN-SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSASPMFKPIFTAPPKSEKEGLTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLAT--SAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********..****** . *:**. ** ******* ***:*:** ****************::************.* *****:.:* * :* *** ****..**.* ***: * ********************:** ** *:*******: **.*.:...:****.**:********* **. ** *.*..************:*:*** *.******** *******.****************** :: **.:.***:.:*******************.******* *** ****:.*************.************.****:**********.* *************:**:***:.: *.*******************:******.**:********************* **** *::****.**.:**** ***.:*.:. *:*. .* .***********:********:********:***********:*::*******:.****.* ** ..*: .*:*.*.**:***:...*:.*:** ***:*********** .* *...*.. ***. * *********.** . :** *.*.* ****.:*:*** .*.* .* **:*:. . **: .... *::*.**:* * *** . :*.** *:*..:.*********.*.****.:. *...*.::*:.:*:: **::::*. **:*:*..: * :::**..** :****:.**:.:*:***:***.:***:**. *:** ****.****:.:.:* *:: * :::**..*** ** .:::* :**:.******** * .::.: *:***.*.::. **:*.* .*****.**:* *****:********** ********.:***..**:*****.**:***::* *:****:************.*.**::**:** :**.*::.*** ***:**:**:***:*****.:*:*****:**:*****:: **: ******:***::**************.*.**:. ****:.:*:*:****:****:..*:*.* .*.**:**:..*.:****.****.*********:******.:*******:********.*:*************.*****************************", "identical_positions": 816, "similar_positions": 289, "identity": "65.38%" }, { "cls_id": "homologset.agr.HGNC:34006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L3E5-1", "uniprot_id": "A0ABK0L3E5_RAT", "id": "A0ABK0L3E5-1", "name": "Pleckstrin homology domain-containing family M member 3", "aln": "----MEALEVDDISPALEVTEDFFSTFDSKLGKAVQQAEVYGVQEVPELVGHEVLGNITDNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLHGPHFPRPSFLLSSSNKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMARQEEKANSPGLGHHVDCAQNHCLQKKSSGLLA-SPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLD--EDPLLSYNVDVCLAVQTDNLDG-CDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAAR----SSEQNLQVTLRNKPKDQLGGHELRKNKRQSVTTS-FLSILTTLSLERGLTAQSFKCAGCQRPIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVARLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGSVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDES-LEEACTMFELSYQNT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BM47-1", "uniprot_id": "PKHM3_MOUSE", "id": "Q8BM47-1", "name": "Pleckstrin homology domain-containing family M member 3", "aln": "----MEALEVDDISPALEVTEDFFSTFDSKLEKAVQQAEVYGIQEVPELVGHEVLGNIADNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMAQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLQGIHFPGPSFLLSSPSKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMGRQGEMANSPGLIHHGDCAQNHCLQKKSSGLLA-SPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLD--EDPLLSYNVDVCLAVQIDNLDG-CDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAAR----SSEQNLQVTLRNKPKDQLDGRELRKNKRQSVTTS-FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDES-LEEACAMFELSYQST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWE6-1", "uniprot_id": "PKHM3_HUMAN", "id": "Q6ZWE6-1", "name": "Pleckstrin homology domain-containing family M member 3", "aln": "----MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTTPLQQQQQQQ-PLLQGPHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLD--EDPLLSYNVDVCLAVQMDNLDG-CDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVAR----SSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTS-FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWQRLNMDES-LEEACTMFELSYQNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UYC9-1", "uniprot_id": "B0UYC9_DANRE", "id": "B0UYC9-1", "name": "", "aln": "----MEGLEVEDISPALEATEDYLHCLDDNHG----DAQVH----PPKLKEASTLDKLNSSGVWG------------------LLTGKQSELSPGNMAWAEQTPFSVLGLRNGKRNRARSTN--DLAAHAKETNSTTN---TSSGGFKRGHNRSRSDVNNRTY--TDNGMPAIDKNMFKNMALN--------------------DHRDAHKESSSYLVKQGTLEQREGPWGRWTACHVELTPCELRLYSLDSSGNQQLCAALSLSHCQGVSAPQPQDGRVLQAVFFNSTRVQLRAPCQWEALEWRRLLWERVLAARPTHSKAEPACANSP---TPHEPDPDAAMVPAPRPLVRPTALPLFTQHCADVLKSGLLHQLTDLNNWRAFTFVLSRTDLQAFPTEGRGPVSEPVLRYQLASCLAVQRDDEDGGRSSRFQVVFPDDVLRLRAENEAKAQDWVEGLRIAVTAQRPQCESTEAPSGVLMRNKPTREKKHKEAQRAKRQSVTTS-FLSILTCLAVEKGLTAQSFRCAGCQRPVGLSRGKAKVCAYSGWYYCTSCHQDNLFLIPARLLHNWDTNRHKVSKQAKEFLEFVYEEPLLDVQQLNPCLYEHCEPLAAVLKLRQQLQSLRAYLFSCRATVAEDLRRRIFPREYLLQHVHLYSLADLQQVIDGKLAPFLSKVIKFASSHVYSCSLCREKGFICELCHTGQVIYPFQENATKRCEGCGAVFHAECRMRAQPCPRCVRRELHKKPASFWKRHGPHDSPDDEVLDCFELDT---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W293-1", "uniprot_id": "Q9W293_DROME", "id": "Q9W293-1", "name": "", "aln": "MSSLFRSLNHFSSKRENVVKEALINTLNENAREIEFEVKQKSLEVLGVCEQTSALCTTLEALFLHG--------------LKDSFLSATFNVIAGDVERRPEPSFWAPCMVFMHKQVIEQVQGLSQITSETGQCRAWVRQSLNESVFSSYLNNMRKNGSALSQYYKRNALMRDSEGLETAAKIMES-----------------LEAYVQFDLPVNSSLLNHWPDYSLQLSDLWTPALKS-CPISSGVDVASSLGS----DIIAIPTPQPLQTNELFSESISNSPFGRNSNFGVPELSQRENLDLLIQKFDEMDVINEEQTGGDKAETNETAEQEAPSGSKTRSRKKSNRQMDS-SSFADLDLEAPSLLPQGSNS----LSNLMQTSWSGDLEATPTSPTEELT--GSRFFQRSVSVSSSVSLRSPTTDRCSYNALLRKHESNRESGAGWSEIWEKFRASASNLNVAQPQRDTDPPISEDLSDLQSLDTNSEFELLTSEFDMVELQQMVAQLCQLAREPGLDAQGFLCKSCQHPLGIGYSNFQVCAFSGSYYCNSCMDVEMQLIPARIIYNWDFRKYSVSKRAATFLAEFRSHPFLDMQLLNPRIYFASDAMAELQSLRIRLNFIRAYLYTCAPSSIELLQNQFAGREYLYEHIHLYSIADLALIQRGVLCQQLQKAFKLGEAHVLKCRLCHLKGFICEICQSPRVLYPFHISTTFRCLACGAVFHAECLNEKQPCPKCERIRKREDQG------------LQEAVQCLKQKNEVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..*: . . ..* : ::.: :.: ..* . . : :: ... : : :: : . : . *. . *.: . . .: : : .. . : : : . * .. . * . . .* *. :. * :.. . : :: : .:.. : . * *: :: : . : : .. . . : :.. . .:* .* .* :: . : . . .: .: . :*. . * :: .: * . . : ... .. : : :. * : : * . ::: * *: * ** **.* * .**:.:*:. .: :** :** ***.** : *****:::*** ::.***:* ** . ..*::*:* *. :* .:.:* : ** :*: :****::* .: * *:.:: **** :::****:*** : * *. * *.:*:. :** .* ** ******:*:. .::***. :* ** .**:***:** . ***:* * . ::. :*. :: . ", "identical_positions": 118, "similar_positions": 209, "identity": "15.23%" }, { "cls_id": "homologset.agr.HGNC:3401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07687-1", "uniprot_id": "HYEP_RAT", "id": "P07687-1", "name": "Epoxide hydrolase 1", "aln": "-------------------------MWLELVLASLLGFVIYWFVSRDKEETLPLGDGWWGPGSKPSAKEDESIRPFKVETSDEEIKDLHQRIDRFRASPPLEGSRFHYGFNSNYMKKVVSYWRNEFDWRKQVEILNQYPHFKTKIEGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKSHGLSDEHVFEVICPSIPGYGYSEASSKKGLNSVATARIFYKLMTRLGFQKFYIQGGDWGSLICTNMAQMVPNHVKGLHLNMAFISRS--FYTMTPLLGQRFGRFLGYTEKDIELLYPYKEKVFYSIMRESGYLHIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLDDLLVNIMIYWTTGTIVSSQRYYKENLGQGIMVHKHEGMKVFVPTGFSAFPSELLHAPEKWVKVKYPKLISYSYMERGGHFAAFEEPKLLAQDIRKFVSLAELQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D379-1", "uniprot_id": "HYEP_MOUSE", "id": "Q9D379-1", "name": "Epoxide hydrolase 1", "aln": "-------------------------MWLELILASVLGFVIYWFVSRDKEETLPLEDGWWGPGSKPSAKEDESIRPFKVETSDEEIKDLHQRIDRFRASPPLEGSRFHYGFNSSYLKKVVSFWRNEFDWRKQVEILNQYPHFKTKIEGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKTHGLSDEHVFEVICPSIPGYGFSEASSKKGLNSVATARIFYKLMSRLGFQKFYIQGGDWGSLICTNIAQMVPNHVKGLHLNMSFISRN--IYSLTPLLGQRFGRFLGYTEKDLELLYPFKEKVFYNIMRESGYLHIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLEDLLTNIMIYWTTGTIVSSQRFYKENLGQGVMVHRHEGMKVFVPTGYSAFPSEILHAPEKWVKVKYPKLISYSYMERGGHFAAFEEPKLLAQDIRKFVSLAELQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07099-1", "uniprot_id": "HYEP_HUMAN", "id": "P07099-1", "name": "Epoxide hydrolase 1", "aln": "-------------------------MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEIHDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVPSHVKGLHLNMALVLSN--FSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYMHIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVMLYWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKLISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAE5-1", "uniprot_id": "A0A8M9QAE5_DANRE", "id": "A0A8M9QAE5-1", "name": "Epoxide hydrolase", "aln": "MGFQDTVLQTIDSVKGTLDNLDRSKLQLLALSSAGVGALLCYLSWRKGPKTIPIGDGWWGAGQK-SLTEDKTIQRFVVKTSVEEIEDLHKRIDLTRFTDPLEDSKFNYGFNSTYLRRVVSYWRHQFNWEKQVKVINQYPHFKTKIEGIDVHFVHVRPLQK-SGQTVVPLMMVHGWPGSFYEFYGIIPLLTKTDSN-----VVFEVICPSIPGYGYSEAPHKKGFNTMEAARIFLKLMERLGFSEFYVQGGDWGAFITSNMAQMKPDCVRGLHLNMVIARTDSTAQLLSLVIGRYLPFLVGFTKEDVRRLYPYMEKNIYDILRETGYLHIQATKPDTAGCGLNDSPVGLAAYILEKFSTWTNLENRDLEDGGLERKFNLDDLLTNVMIYWTTCSIIPSMRFYKENLKKDFKTRVDRVTSIHVPTGLAAFPDELLHCPRAWASSRFSDVRSFTYMPRGGHFAAFEEPQLLAQDIIQFAEKVEGKSHKSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : :: :* : :: *. :*:*: *****.* : : **.:*: * *:** ***.***:*** * : ***.* *:*****.*:::*:*:**::*:*.***:::*:**********:*:**:**:* * :*:* **:************* ******....: *************:***. ***:*:: :**** *** ****.:**:******::* :*:**: *. *:****** : . :: ::*: : ::* *:.*:. *** ** :*.::**:**:***.*****.*..********************: * * **********.*:***.*:*:**** :*:.* *:***** :. .: .. .:.**** :*** *:** *. *. ::..: *::** ***********:****** :* . * : ", "identical_positions": 247, "similar_positions": 124, "identity": "50.72%" }, { "cls_id": "homologset.agr.HGNC:3402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34914-1", "uniprot_id": "HYES_MOUSE", "id": "P34914-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFP--EAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSG--PALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80299-1", "uniprot_id": "HYES_RAT", "id": "P80299-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITFSQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTCIVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFP--EAPLPVPCSPNDVSHGYVTVKPGIRLHFVEMGSG--PAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNTPLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTVNKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKALGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILIKWLKTEIQNPSVTSKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34913-1", "uniprot_id": "HYES_HUMAN", "id": "P34913-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSG--PAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53750-1", "uniprot_id": "YN93_YEAST", "id": "P53750-1", "name": "Uncharacterized hydrolase YNR064C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNIIAR----------------------------------FHKIQVQDGVKVWYREAGAAGNPTILLLHGFPTSSNMFRNLIPLLAGQ-FHIIAPDLPGFG-FTETPENYKFSFDSLCESIGYLLDTLSIEKFAMYIFDYGSPVGFRLALKFPSRITGIVTQNG-----NAYEEGLDDRFWGPLKEYWKSYQSDPVFVKSLIPYLEDPANVICQYHDGVPAIES-----------VDPAAYTLDIALIQRTGQTDIQLRLFFDYQNNIKLYP--------AFQKFLRDSKIPVLVAWGANDTIFSVAGAEAYRKDVDNLKVVYYDTG-HFALETHVVAIAEEIISMFAEN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*:.: . : *: ::: : * *:. *:: * **** * :* ** ** ::::* *: *:* : .** ::.:: **:.: :*:.*.: : .: .*:.. : : :** .*.*: .:.: * :. . :. *: :* :*. * .* :. . : : : * : * .:. :. : :* .::. :: * : : : *. :*.*:. . :* :: :: .. : ** : : *:: : . : : :*. : : ", "identical_positions": 50, "similar_positions": 113, "identity": "8.96%" }, { "cls_id": "homologset.agr.HGNC:34024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JZM6-1", "uniprot_id": "TIFAB_MOUSE", "id": "Q8JZM6-1", "name": "TRAF-interacting protein with FHA domain-containing protein B", "aln": "MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BK67-1", "uniprot_id": "TIFAB_RAT", "id": "Q5BK67-1", "name": "TRAF-interacting protein with FHA domain-containing protein B", "aln": "MERPLTVLQVSLYHPTQGPVAFAKVPLQLQHDASRLLVGRGQDTHLQLQLPQLSRHHLCLEPYLEKGSNLLAFCLKVLTRQSCVWVNGLPLRYLEQVPLHSVNRISFSGIQMLIRKEGGASLEAFVCYFHLSPSPLIYRPKAQETDE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZNK6-1", "uniprot_id": "TIFAB_HUMAN", "id": "Q6ZNK6-1", "name": "TRAF-interacting protein with FHA domain-containing protein B", "aln": "MEKPLTVLRVSLYHPTLGPSAFANVPPRLQHDTSPLLLGRGQDAHLQLQLPRLSRRHLSLEPYLEKGSALLAFCLKALSRKGCVWVNGLTLRYLEQVPLSTVNRVSFSGIQMLVRVEEGTSLEAFVCYFHVSPSPLIYRPEAEETDEWEGISQGQPPPGSG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****:******* ** ***:** :****:* **:****::*******:*** **.********* *******.*:*:.*******.********* ::**:********:* * *:***:******:*********:*:**** ", "identical_positions": 114, "similar_positions": 24, "identity": "70.81%" }, { "cls_id": "homologset.agr.HGNC:34026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29418-1", "uniprot_id": "ATP5E_RAT", "id": "P29418-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGTSIKTVKIKKE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R601-1", "uniprot_id": "M0R601_RAT", "id": "M0R601-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWQQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGSSIKTVKVKKPD-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56382-1", "uniprot_id": "ATP5E_MOUSE", "id": "P56382-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGSSIKIVKVSKKE-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTU8-1", "uniprot_id": "AT5EL_HUMAN", "id": "Q5VTU8-1", "name": "ATP synthase subunit epsilon-like protein, mitochondrial", "aln": "MVAYWRQAGLSYIRYSQICAKVVRDALKTEFK-ANAKKTSGNSVKIVKVKKE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXN2-1", "uniprot_id": "SUN_DROME", "id": "Q9VXN2-1", "name": "Protein stunted", "aln": "-MTAWRAAGITYIQYSNIAARILRESLKTGLR-ADAAKRDASHVKFTPWANGKPAQR---QTQSES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH24-1", "uniprot_id": "Q9VH24_DROME", "id": "Q9VH24-1", "name": "", "aln": "-MKAWRDLGITYIQYSNIAARVVREALRIELR-ADAAKRNISHVKFTPWVNGKPVPRKKVERESES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21306-1", "uniprot_id": "ATP5E_YEAST", "id": "P21306-1", "name": "ATP synthase subunit epsilon, mitochondrial", "aln": "-MSAWRKAGISYAAYLNVAAQAIRSSLKTELQTASVLNRSQTDAFYTQYKNGTAASEPTPITK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: *::* : ::.*: :*.:*: :: *.. : . . . : ", "identical_positions": 7, "similar_positions": 22, "identity": "10.61%" }, { "cls_id": "homologset.agr.HGNC:3403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00262-1", "uniprot_id": "STX2_MOUSE", "id": "Q00262-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRTNDDGDTAVVI-VEKDH-FMDGFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLDKEIKKTANRIRGKLKSIEQSCDQ--DENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGRTTTDDELEEMLE-SGKPSIFISDIISDSQ--ITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVAVAVIAVLALIIGLSVGK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50279-1", "uniprot_id": "STX2_RAT", "id": "P50279-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRKSDDGDNAVIITVEKDH-FMDAFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANRIRGKLKAIEQSCDQ--DENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGRTTTDEELEEMLE-SGKPSIFISDIISDSQ--ITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVVVAVIAVLALIIGLTVGK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32856-1", "uniprot_id": "STX2_HUMAN", "id": "P32856-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRKNDDGDTVVVV--EKDH-FMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQ--DESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLE-SGKPSIFTSDIISDSQ--ITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEN6-1", "uniprot_id": "A0A8M2BEN6_DANRE", "id": "A0A8M2BEN6-1", "name": "", "aln": "-MRDRLADLNVGRHNASEDGGVAVSMERND-FMQDFFQKVEEVRRVIEKISSLVDEVKKKYSVILSAPNPDEKTKEELEQLTVEIKKHANYVQKSLKSMHQSLPS--DEQVNQASVDARIQKTQYTNLSHKFVEVMTQYNEAQVSFREKSKSRIQRQLEITGKITTNEELEEMLE-TGNPSIFTSDIISDSQ--ITRQALNEIESRHQDILRLESSIKELHDMFVDMAMLVETQGEMIDNIEKNVHNAVEYVGQAKVETKKAVRYQTRARR-KWVYGAICGAVCIIILLLIIITAVYVD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "MTKDRLAALHAAQSDDEEETEVAVNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQ--EEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLE-EGNSSVFTQGIIMETQ--QAKQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARR-KKIMILICLTVLGILAASYVSSYFM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ACD6B5X7-1", "uniprot_id": "A0ACD6B5X7_DANRE", "id": "A0ACD6B5X7-1", "name": "", "aln": "-MKDRLGELSAHYND------ITIDVESDA-FLEKFLPKVDEAQKLIERLSFLVEEVKLRHRTILTEINPQAYVRDELELFGNDIKQIADAIQVKLKDLEEHFSKYGNANTNSSSVYCRIHTTQHTVLSLRFAEIMGLYNQELLYFRAKSKERIQRQLEISGNVMTEEETEDLLQ-NKSPAVFTSNISSGSS--ITGQALNEIESRHKDIRCLEASIQELHNMFTDIAMLVNSQGEMANNIAKTVMKTGNYVDQGKENIKQATEYKKSWRIRLPPLPSFKRKAKPVTNEGLLNES-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "id": "P32867-1", "name": "Protein SSO1", "aln": "MSYNNPYQLETPFEESYELDEGSSAIGAEGHDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQ--ASHLRHSLDNFVAQATDLQFKLKNEIKSAQR--------DGIHDTNKQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * . . . : *: ::.: . : : :::*. : :*: : : ..*. :: * :: .** : . : :* :* . : *. :: . * : :** * .::* * :. :* . : . : :* ::::**::: ** *: ** ::* *: :* * * : * * .: * . . .:* . * . : ", "identical_positions": 36, "similar_positions": 77, "identity": "12.0%" }, { "cls_id": "homologset.agr.HGNC:34032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M700-1", "uniprot_id": "F1M700_RAT", "id": "F1M700-1", "name": "", "aln": "MASEVTRDGSWCSLLQELWQGADITKKGQQNQILPFPPVSFLKKTLSKNSGHDYQKPGETIPLRSYLISTQEGLPQYCSLPKSLDLNLGANGPNERDRLIDIVASSQLLMPGSCNADRVVPHGGESYRSTGNGDVLSHKQPLIYGNHFQEKADQGSQCQEVLYAISLHKPEITLTVDRPIASYSGGKVFLYVSDSLSHPFQLKVDHLVHTGGDPYKCSSCEESFCTEAALQQHEQIHTEEKPYVCTLCGKAFSDGSAFYEHELIHKNHTPFICDICGKAFLRKSELTSHKQSHSGEKPYKCNDCGKSFKFPSQLKVHRQIHTGEKPYECRECGKSFSKTAKLKVHQRIHTGEKPYVCSQCGKAFNQKSILDRHEKLHPGEKPYKCSDCGKSFNYPSQLKVHCHSHTGEKPYKCHECGKSFNFPCELKVHYQNHTGEKPYKCRECWKLFSKMSQLKAHYRVHTGERPYKCSHCGKAFSTKEQVQEHERIHTGEKPFVCTECGKAFSSRSSFRKHQLIHTKEKPFVSQKCETGLQESTLTPHQQLHIGEKPYKCPDCGKLFNYPSQLKSHYQIHTGEKPCKCPDCGKSFSKTSQLKAHSRIHTGERPYVCSVCGKAFKQLSTLSRHEKIHMVEKPYKCNFCGKSFCSPSELKVHLLIHTGERPYKCNSCWKAFCTKVQLQEHERIHTGERPYVCTHCGKAFRSRSVFSKHKLIHRKVTPFICERCGKVFLQKSELTSHLQTHIEDKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3KNS6-1", "uniprot_id": "ZN829_HUMAN", "id": "Q3KNS6-1", "name": "Zinc finger protein 829", "aln": "---------------------------------MPHSP----------------------------LIS----IPHVWCHPEEEER--------MHDELLQAVSKGPVMFR-----DVSIDFSQEEWECLDADQMNLYKEVMLEN--FSNLVSVG---------LSNSKPAVISLLEQ-------GKEPWMVDRELTR------------------------GLCSDLESMCETKILSLKK--------RHFS-------QVIITR------EDMS--TFIQPTFLIPPQKTMSEEKPWECKICGKTFNQNSQFIQHQRIHFGEKHYESKEYGKSFSRGSLVTRHQRIHTGKKPYECKECGKAFSCSSYFSQHQRIHTGEKPYECKECGKAFKY--------------------------------------------------------CSNLNDHQRIHTGEKPYECKVCGKAFTKSSQLFLHLRIHTGEKPYECKECGKAFT---------------------------QHSRLIQHQRMHTGEKPYECKQCGKAFNSASTLTNHHRIHAGEKLYECEECRKAFIQSSELIQHQRIHTDEKPYECNECGKAFNKGSNLTRHQRIHTGEKPYDCKECGKAFGSRSDLIRHEGIHTG---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..* *** :*: . *:. : :*.*:: *:.. ::: * : .. *.:.. . .:: :*: :: . *.: .. * :* ** : ::: ** *. .*:: .:*:: . :* : :* : ** : :* : *:. :*:: : * . ::: * ***::*: ***:*: **: *::** *** **.:* *****: : :. *******:*** *.:*****. .* :.:*:::*.*****:*.:***:*:* *:*: * *:****:**:*. *****:...*: * ********: *.******: *.* * **::* *****:* :*** ** .* *..*::**:*** :* :* *:* ::*:* *.****.*:** *. *****:: *.*:**::** ****.*: ***:* * *:* * **** ", "identical_positions": 187, "similar_positions": 146, "identity": "25.1%" }, { "cls_id": "homologset.agr.HGNC:34059", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYD3-1", "uniprot_id": "F1LYD3_RAT", "id": "F1LYD3-1", "name": "", "aln": "------MDSCPAG-PLGLICLSLVLIPASAGTYCECSLGLSREALIALIVVLAGISASCFCALVVVALGVFRAKDDTCPGHSENRLEEPYGVQEDQIDLHTVHVESHLMDPDLEVSMMQSLENQTLTAMTAPLQPPPPPPPPPPPPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2F0-1", "uniprot_id": "TM210_MOUSE", "id": "Q9D2F0-1", "name": "Transmembrane protein 210", "aln": "MAPCPQPESCPAGSPLGLICLSLLLIPASAGTYCECSLGLSREALIALIVVLAGVSASCFCALVVVAIGVFRAKGDTCPGHSENRLVGPYGVQEDRIDLHTVHVESHLMDPDLDVSMMPSLDGPGLMTMTAPLEPPPPPPPPPPLPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NLX4-1", "uniprot_id": "TM210_HUMAN", "id": "A6NLX4-1", "name": "Transmembrane protein 210", "aln": "MAPGPWPVSCLRGGPLGLTYLSLLLIPAAAGTYCECSLGLSREALIALLVVLAGISASCFCALVIVAIGVLRAKGETCPRQVDNRLVENFGVQEDLMDLHPVYVESQLMDADLEVSLVPPLEDQSLVAIPMEASSEEPPPPPPLPPE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * **** ***:****:*******************:*****:*********:**:**:***.:*** : :*** :***** :***.*:***:***.**:**:: .*:. * ::. .. ****** * ", "identical_positions": 88, "similar_positions": 28, "identity": "59.86%" }, { "cls_id": "homologset.agr.HGNC:34071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD22-1", "uniprot_id": "D4AD22_RAT", "id": "D4AD22-1", "name": "", "aln": "------------MWIFSLLCVLLITLSADH--VDTKAKTT--PYSKFTKKFEGKE----TLKGLKPSSGLSLDEEETLRTEMAAMAEPTTGSPALATADPTTGPSASATTRLLP---LESFSLDTANFFLNCCHCCSFVTVQKGEPGKTGQQGPKGETGDTGSPGPPGTSGPQGPKGQKGEKGLKGDRGDQGAGGIPGYPGKPGEQGALGLKGDKGNIGPAGTKGQKGSKGDLCGNGTKGEKGDPGASGAHGFIGQPGAKGEKGGVGEKG------YRGDSGQRGEKGQKGEKGMEGEKGSKGDVGAEGKRGSDGLPGLRGDPGPKGEKGETGSPGFTGPAGPKGELGNKGVRGP---TGKKGSRGMKGSKGEATQVPQSAFSALLS--KPFPPPNIPIKFDKILSNDQGDYSPVTGKFNCSVPGTYIFSYHVTVRGRPARISLMARNRKQFKSRETLYGQQVDQASLLLVLKLSAGDQVWLEVSKDWNGLYVGPEDDSIFSGFLLYPEETLRKSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4ZJM7-1", "uniprot_id": "OTOL1_MOUSE", "id": "Q4ZJM7-1", "name": "Otolin-1", "aln": "------------MWIFSSLCAVLTILAMDD--VATEAKTT--PYTKFTKKSEGKE----MLKGLKPSSGFFLDGEETVHTETAAMAEPTTGSPALAMAESTAGPSASATTRLLP---FESFSLDTTGFVLNCCHCCSFVTGQKGEPGKMGKQGPKGETGDTGSPGHPGTTGPQGPKGQKGEKGLKGDRGDQGAGGIPGYPGKPGEQGALGPKGDKGTIGPAGTKGQKGSKGELCGNGTKGEKGDPGASGAHGFIGEPGAKGEKGGVGEKG------YRGDLGERGEKGQKGEKGMEGEKGSRGDVGSEGKRGSDGLPGLRGDSGPKGEKGEIGSPGFTGPAGPKGELGSKGVRGP---TGKKGSRGVKGSKGEATQVPQSAFSALLS--KPFPPPNVPIKFDKILSNDQGDYSPVTGKFNCSVPGTYIFSYHVTVRGRPARISLVARNRKQFKSRETLYGQQVDQASLLLILKLSAGDQVWLEVSKDWNGLYVGPEDDSIFSGFLLYPEETFSKSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHN0-1", "uniprot_id": "OTOL1_HUMAN", "id": "A6NHN0-1", "name": "Otolin-1", "aln": "------------MWMFSWLCAILIILAIAG--MNTIAKTT--PHTKFTKKSEERE----MPKGLKPSSGPPPEEEETLFTEMAEMAEPIT--------KPSALDSVFGTATLSP---FENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQ---GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGP---TGKKGSRGFKGSKGELARVPRSAFSAGLS--KPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARISLVAQNKKQFKSRETLYGQEIDQASLLVILKLSAGDQVWLEVSKDWNGVYVSAEDDSIFTGFLLYPEETSGISP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PN28-1", "uniprot_id": "OTO1A_DANRE", "id": "A5PN28-1", "name": "Otolin-1-A", "aln": "MPN-----------ILHPFIIIMTLLVVATGNQASIDKTTQWPRMKPTKKPPPRDEGPSKLGSISTTVSPTAIGITEEVTDAMMDAYTITSTGSTTFSSDTYSADYHTEAMVPPGVGPGNYTLDYNECFFNFCECCPPERGPPGPVGEKGLPGIPGGKGEMGPPGPPGQEGLTGAPGTHGVKGEKGDTGASGLPGIPGVTGKQGEKGESGPKGDKGDTGFPGLKGDPGERGEPGWNGTKGGMGEPGKQGLTGPPGPDGIKGEKGDKGDC----------PFGEKGQKGSIGEPGPQGPKGDPGVPGTNGTDGLPGSKGPKGDPGPLSKQGEPGPPGPQGPPGQRGMPGMKGTRG---LKGARGIRGFKGFKGEPAVQKRSAFSVGLFPSRSFPPPGLPIRFDKIIYNEEAHWDPNASKFNCTHGGVYVFSYYITVRNRPLRAALVVNGIRKLRTRDSLYGQDIDQASNMAVLRLSSGDQVWLETLRDWNGVYSSSEDDSTFSGFLLYADATKD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FAJ7-1", "uniprot_id": "E7FAJ7_DANRE", "id": "E7FAJ7-1", "name": "", "aln": "MLSSLLFLDRQKMGMFCARSVLVTVLALTFIILCDTFKPTQRPKYQYTKKPP-RE----VVQTTTYAGKPTVTARIVDYTKTREQRTPVYVTESTTVTADSY-IDYPTDTSASPTAAKDNYTLDYNECYFNFCECCPPEKGPQGFKGDMGLPGPPGEKGAPGPSGLPGPIGPKGNSGSKGDKGEKGDQGNTGFAGTPGNQGKAGMKGEMGNKGEKGAAGLPGFKGEKGEKGDPNFNVSKGDQGEPGKDGLPGPQGSAGEKGEKGERGECG---------LLGDRGQKGEPGDPGSPGVRGDPGPSGQHGMHGNPGITGERGEPGTPGPKGEPGIQGPPGTKGLRGLRGIKGDRGPQGKRGDRGLRGMKGAMGTSDSRIRSAFSVGLYPSKSFPPSGFPVRFDKVFYNGENHYDVVSCKFNCSYSGVYVFSYQITVRNKPLRASLVVNGVRKVRSRDTLQPQDIDQASNLVILKLDVGDQVWVETLRDWNGVYSSSEDDSTFSGFLLYPD-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: * *.* * : *** :: . : *. . : . : * .::** :* *.**. * *. * * * * * .* ** * * * :* ** **: * * ** ** * :* * **:** * * **: *.:*: * :** *: * * * * * ***** *: *::* **. *: * * :*. * * .* * * * :*:.* . :** * * *. * :* * ** ** * :* **.** * :****. * :.***...*::*:*:: * : .:. : ****: *.*:*** :***.:* * :*:... ::.::*::* *::**** : :*:*. *****:*. :****:* ..**** *:*****.: ", "identical_positions": 159, "similar_positions": 100, "identity": "30.81%" }, { "cls_id": "homologset.agr.HGNC:34072", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4ZJN1-1", "uniprot_id": "C1QT9_MOUSE", "id": "Q4ZJN1-1", "name": "Complement C1q and tumor necrosis factor-related protein 9", "aln": "------------------------------------MRIWWLLLVMGACTRSVFSQDTCRQGHSGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGHPGGPGKDGIRGEKGEPGADGRVEAKGIKGDPGSRGSPGKHGPKGSIGPTGEQGLPGETGPQGQKGDKGEVGPTGPEGLMGSTGPLGPKGLPGPMGPIGKPGPRGEAGPMGPQGEPGVRGMRGWKGDRGEKGKVGEAPLVPKSAFTVGLTVISKFPPPDAPIKFDKILYNELNHYNVATGKFTCHVAGVYYFTYHITVFSRNVQVSLVKNGVKVLHTKDSYMSSEDQASGGIVQELKLGDEVWMQVTGGERFNGLFADEDDDTTFTGFLLFSSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ76-1", "uniprot_id": "D3ZJ76_RAT", "id": "D3ZJ76-1", "name": "", "aln": "MVGRLDFIYSVRVPYSSQCLYPACNSRVKSRPCRLTMRIWWLLLVMDAG--SVFSQDTCRQGHSGIPGTPGHNGLPGRDGRDGAKGDKGDTGEPGHPGGPGKDGIRGEKGEPGADGRVEAKGIKGDPGSRGSPGKHGPKGSIGPTGEQGLPGETGPQGQKGDKGEVGPTGPEGLMGSTGPLGPKGLPGPVGPIGKPGPRGEAGPMGPQGEPGVRGMRGWKGDRGEKGKVGEAPMVPKSAFTVGLTVISKFPPPDVPIKFDKILYNEQNHYNVATGKFTCHVAGVYYFTYHITVFSRNVQVSLVKNGVKVLHTKDGYMSSEDQASGGIVLELKLGDEVWMQVTGGERFNGLFADEDDDTTFTGFLLFSSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RNN3-1", "uniprot_id": "C1T9B_HUMAN", "id": "B2RNN3-1", "name": "Complement C1q and tumor necrosis factor-related protein 9B", "aln": "------------------------------------MRIWWLLLAIEICTGNINSQDTCRQGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIGETLVLPKSAFTVGLTVLSKFPSSDVPIKFDKILYNEFNHYDTAVGKFTCHIAGVYYFTYHITVFSRNVQVSLVKNGVKILHTRDAYVSSEDQASGSIVLQLKLGDEMWLQVTGGERFNGLFADEDDDTTFTGFLLFSSQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********.: .: *********.****.*********************:**** **.***** ***** ****:********* ************* ** **:** **********:**:******** *. *****.*****:********:***** **********:************:**: ::***********:****..*.*********** ***:.*.******:***************************:***:*.*:********.** :******:*:*****************************.", "identical_positions": 273, "similar_positions": 38, "identity": "73.98%" }, { "cls_id": "homologset.agr.HGNC:34073", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMI7-1", "uniprot_id": "D3ZMI7_RAT", "id": "D3ZMI7-1", "name": "", "aln": "MGGEMLSQTYMGGEMPWTILLFASGSLAIPAPSIFLVPPFPSSREDPIYLSCTAPKDILGANFTLFRGGEAVQLLQAPSDQHSVTFNVTGSGSGGSNEAAGGNFRCQYGVLGEHSEPQLSDFSQEVQVSFPVPTWILALSLSLAGAV-LLSGLVVIAVLVRKAKAKNLQMQRERESCWAQINFTNTDMSFDNSLFAISTKMTQEDSMVTLD-----------SGPRKRPTSASFSPEPPEFSTFRACQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q75VT8-1", "uniprot_id": "HIDE1_MOUSE", "id": "Q75VT8-1", "name": "Protein HIDE1", "aln": "--------------MPWTILLFASGSLAIPAPSISLVPPYPSSHEDPIYISCTAPGDILGANFTLFRGGEVVQLLQAPSDRPDVTFNVTGGGSGGGGEAAGGNFCCQYGVMGEHSQPQLSDFSQQVQVSFPVPTWILALSLSLAGAV-LFSGLVAITVLVRKAKAKNLQKQRERESCWAQINFTNTDMSFDNSLFAISTKMTQEDSVATLD-----------SGPRKRPTSASSSPEPPEFSTFRACQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MVS5-1", "uniprot_id": "HIDE1_HUMAN", "id": "A8MVS5-1", "name": "Protein HIDE1", "aln": "--------------MPWTILLFAAGSLAIPAPSIRLVPPYPSSQEDPIHIACMAPGNFPGANFTLYRGGQVVQLLQAPTDQRGVTFNLSG----GSSKAPGGPFHCQYGVLGELNQSQLSDLSEPVNVSFPVPTWILVLSLSLAGALFLLAGLVAVALVVRKVKLRNLQKKRDRESCWAQINFDSTDMSFDNSLFTVSAKTMPEEDPATLDDHSGTTATPSNSRTRKRPTSTSSSPETPEFSTFRACQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********:********** ****:***:****:::* ** :: ******:***:.*******:*: .****::* *..:*.** * *****:** .:.****:*: *:**********.********: *::***.::::***.* :*** :*:********** .**********::*:* *:. .*** * .******:* ***.**********", "identical_positions": 150, "similar_positions": 50, "identity": "60.48%" }, { "cls_id": "homologset.agr.HGNC:34075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AS40-1", "uniprot_id": "A0A8I6AS40_RAT", "id": "A0A8I6AS40-1", "name": "", "aln": "MFSCCLRTTRGSGLKKDNREGHGGVWRHRVRSCLRRLWPFSRKVRSSTKTSQSHEHTDKSENDS----------AAQDLSESYRDSSISTEAVVKLGNKLGPSLQEGDTFYVPAFSIIYQRF-----DTPLLVLDQLFLRYANFSPYCEEDEQINNALCSFLETWMDKNTEDYCEPSE--------------------------------------LFILKYIKAYFDVCMAHLDLSVQVNRFMTLLQDNQAKDSHPRMSKAQI-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MXV6-1", "uniprot_id": "CD15L_HUMAN", "id": "A8MXV6-1", "name": "CMT1A duplicated region transcript 15 protein-like protein", "aln": "MFSCCFPTSRGCCFRNGGSESLFRQCRRRLIPHPRRLWPFVRRRTQVPQDSPGQALAGQATPEIPSGLPLHIVLVQEEIREPMEAQTHAPGPYADIAALAAPAVEPKPAWEEPPPERALEVEGAPAKDQPSQELPEIMAPTVATGLNAGAENVAGERSGREGVTSTAPASRSHAAPSPGHGGKHGGGDQGIQTGLLYLAGERLLSFAGTTALLLQGLFIVLILVGYISVKVMLKSIKTRLGRRVPAAPPALRRNLLLQAWKCVCNWASRLFAPNVLPRTGS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****: *:**. :::.. *. *:*: . ****** *: . .: * .: :.:: : . ::: *. . .: :. . ..:. .*::: :: *. . : * * * ::: . . . :: .: * :..:. ** ***: : .*:.* : .:..::.* :. :: : *. ", "identical_positions": 35, "similar_positions": 81, "identity": "12.46%" }, { "cls_id": "homologset.agr.HGNC:341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09139-1", "uniprot_id": "AGT1_RAT", "id": "P09139-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "MFRMLAKASVTLGSRAASWVRNMGSHQLLVPPPEALSKPLSIPKRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMFQIMDEIKQGIQYVFQTRNP---LTLVVSGSGHCAMETALFNLLE---PGDSFLVGTNGIWGIRAAEIAERIGARVHQMIK-KPGEHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQP-LDGFGELCHRY--QCLLLVDSVASLGGVPIYMDQQGIDILYSGSQKVLNAPPGISLISFNDKAKSKVY--SRKTKPVSFYTDITYLSKLWGCEGKTR-VIHHTLPVISLYCLRESLALISEQGLENSWRRHREATAHLHKCLRELGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFNIEISGGLGPSED-KVLRIGLLGYNATTENADRVAEALREALQHCPK------NKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35423-1", "uniprot_id": "AGT1_MOUSE", "id": "O35423-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "MFRMLAKASVTLGSRAAGWVRTMGSYQLLVPPPEALSKPLSVPTRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMLQIMEEIKQGIQYVFQTRNP---LTLVVSGSGHCAMETALFNLLE---PGDSFLTGTNGIWGMRAAEIADRIGARVHQMIK-KPGEHYTLQEVEEGLAQHKPVLLFLVHGESSTGVVQP-LDGFGELCHRY--QCLLLVDSVASLGGVPIYMDQQGIDIMYSSSQKVLNAPPGISLISFNDKAKYKVY--SRKTKPVSFYTDITYLAKLWGCEGETR-VIHHTTPVTSLYCLRESLALIAEQGLENCWRRHREATAHLHKHLQEMGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFSIEISGGLGPTEE-RVLRIGLLGYNATTENVDRVAEALREALQHCPK------NKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21549-1", "uniprot_id": "AGT1_HUMAN", "id": "P21549-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "----------------------MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNP---LTLVISGSGHCALEAALVNVLE---PGDSFLVGANGIWGQRAVDIGERIGARVHPMTK-DPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQP-LDGFGELCHRY--KCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMY--SRKTKPFSFYLDIKWLANFWGCDDQPR-MYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTG-KVLRIGLLGCNATRENVDRVTEALRAALQHCPK------KKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3Z3-1", "uniprot_id": "AGT_DROME", "id": "Q9W3Z3-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "---------------------------MEVPPPLVLKRPLYVPSKTLMGPGPSNCSHRVLEAMSNPVLGHMHPECLQIMDEVKEGIKYIFQTLND---ATMCISGAGHSGMEAALCNLIE---DGDVVLMGITGVWGHRAGDMARRYGAEVHYVEA-SFGRALSHEEITFAFEAHRPKVFFIAQGDSSTGIIQQNIRELGELCRKY--DCFLIVDTVASLGGTEFLMDEWKVDVAYTGSQKSLGGPAGLTPISFSKRALTRIR--KRKTKPKVYYFDILLIGQYWGCYGTPR-IYHHTISSTLLYGLREALAHFCAVGLKAVVRRHQECSKRLQLGIEELGLEMFVSREEERLPTVNTIKVPFGVDWKKVAEYAMRKYSVEISGGLGPTVE-HVFRIGLMGENATVERVDMVLSILNEAIQSSKLGIKTDLSKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43567-1", "uniprot_id": "AGX1_YEAST", "id": "P43567-1", "name": "Alanine--glyoxylate aminotransferase 1", "aln": "---------------------------------------MTKSVDTLLIPGPIILSGAVQKALDVPSLGHTSPEFVSIFQRVLKNTRAVFKSAAASKSQPFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVVRPLKIGESVPLELITEKLSQNSYGAVTVTHVDTSTAVLSD-LKAISQAIKQTSPETFFVVDAVCSIGCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLRRWTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEEGLHKRWDLHREMSDWFKDSLVN-GLQLTSVSRYPSNMSAHGLTAVYVADPPDVIAFLKSHG-VVIAGGIHKDIGPKYIRIGHMGVTACNKNLPYMKNCFDLIKLALQR------KK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: *** . : * . :* : .*::.: :. : :*:: .: ::*:* . : *.: .. .* .* :. * : **.*. : . * . : : : : . :.: ::**.::. : :.: :: . :::**:*.*:* : :*. :*. :.*** :..*.* : ..: .:: : :: .: : . * . : * :* : **. *:* : :: : **:: : : . : .: : : : * **: : :*** :* .* :. : . : .* ", "identical_positions": 50, "similar_positions": 124, "identity": "11.52%" }, { "cls_id": "homologset.agr.HGNC:3413", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XQ2-1", "uniprot_id": "EPM2A_RAT", "id": "Q91XQ2-1", "name": "Laforin", "aln": "-------MLFRFG-VVVPPAVAGTRLELLLAGSR-PELGRWEP---RGAVRLRPAGTAAGAAALALQEPGLWLAEVELAPEEEAADGAEPGRIDTFWYKFLQREPGGELHWEGNGPHHDRCCTYNENNLVDGVYCLPVGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQLEHVTIKLKHELGITAVMNFQTEWDIIQNSSGCNR-YPEPMTPDTMMKLYKEEG---LAYIWMPTPDMSTEGRVQMLPQAVCLLHALLENG----HTVYVHCNAGVGRSTAAVCGWLHYVIGWSLRKVQYFIMAKRPAVYIDEEALAQAQQDFFQKFGKVHSSICTL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUA5-1", "uniprot_id": "EPM2A_MOUSE", "id": "Q9WUA5-1", "name": "Laforin", "aln": "-------MLFRFG-VVVPPAVAGARQELLLAGSR-PELGRWEP---HGAVRLRPAGTAAGAAALALQEPGLWLAEVELEAYEEAG-GAEPGRVDTFWYKFLQREPGGELHWEGNGPHHDRCCTYNEDNLVDGVYCLPVGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQLEHVTIKLKHELGVTAVMNFQTEWDIIQNSSGCNR-YPEPMTPDTMMKLYKEEG---LSYIWMPTPDMSTEGRVQMLPQAVCLLHALLENG----HTVYVHCNAGVGRSTAAVCGWLHYVIGWNLRKVQYFIMAKRPAVYIDEDALAQAQQDFSQKFGKVHSSICAL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BHX0-1", "uniprot_id": "A0A8M2BHX0_DANRE", "id": "A0A8M2BHX0-1", "name": "Laforin", "aln": "-----MMVVFRFG-VILTPECP--DIEVFVLGSR-PEMGLWDT---ERAVKMNPS------QGRSCREPCLWTGDVLLS---------EP-LTDPLWFKFIKRVDG-DFIWEGSGPHHNRCCVYDDRNMVDGIHCHPIGHWIQETGHTDEMKHTTNFYFSIAGQQAMHFSQVLPRVWLGSCPRRVEHVTLKLKQELGVTAVMNFQTEWDVINNSHGCRRDLSQPMTPETMMHLYRDSG---LSYIWMPTQDMSTEGRIQMLPQAVFLLFGLLENG----HSVYVHCNAGVGRSTAAVCGLLMYVFGWKLRKVQYFLTARRAAVYIDEEALLRARDDFHMKFGQLCPSVRNTETQDSTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B3EWF7-1", "uniprot_id": "EP2A2_HUMAN", "id": "B3EWF7-1", "name": "Laforin, isoform 9", "aln": "MHPKEGAEQHVFSPVPGAPTPPPNRCGRLVLGPRLPAAGTPGPGIRAAAARHALPLWGGGATRRGRRPAGAAGGGVAARAGALGAARCRP--PEAGRHRGGRRGPG----PAGAGPVARGGGAGGRGGGAGRGGAGPRGHVLVQVPEAGAGRRALLGRYCQQTPAPGAERELRPAPPTGASASGRPRRPRRRASRAFCPRPCALPGRPGLTLLCRPRCRRQPRLRLPTDSLDPYSAPGRLPAHSVACPSDLVSAHPVLSFFPTAPASRASALRLPPGAPFALRVPLDLRVPPFAGPLAARPRAADGFNSPTPPWLGFVSSFSCSNSLKKTQNDPTNETSVFANPRQQCAT--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. * .* . :: *.* * * . *.: . . : . . * .* :. .: :* * * ** . . . .. . * ** : . .:. ::: : . .: * *:.. : . : . . : . .: . * .. * :. * * : *: :*:. :.::* * . *. .:: * : * :..:.. . *:. . :: . : . . . : *.: . ", "identical_positions": 33, "similar_positions": 92, "identity": "9.22%" }, { "cls_id": "homologset.agr.HGNC:3415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29676-1", "uniprot_id": "EPO_RAT", "id": "P29676-1", "name": "Erythropoietin", "aln": "MGVPERPT-LLLLLSLLLIPLGLPVLCAPPRLICDSRVLERYILEAKEAENVTMGCAEGPRLSENITVPDTKVNFYAWKRMKVEEQAVEVWQGLSLLSEAILQAQALQANSSQPPESLQLHIDKAISGLRSLTSLLRVLGAQK-ELMSPPDATQAAPLRTLTADTFCKLFRVYSNFLRGKLKLYTG--EACRRGDR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07321-1", "uniprot_id": "EPO_MOUSE", "id": "P07321-1", "name": "Erythropoietin", "aln": "MGVPERPT-LLLLLSLLLIPLGLPVLCAPPRLICDSRVLERYILEAKEAENVTMGCAEGPRLSENITVPDTKVNFYAWKRMEVEEQAIEVWQGLSLLSEAILQAQALLANSSQPPETLQLHIDKAISGLRSLTSLLRVLGAQK-ELMSPPDTTPPAPLRTLTVDTFCKLFRVYANFLRGKLKLYTG--EVCRRGDR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01588-1", "uniprot_id": "EPO_HUMAN", "id": "P01588-1", "name": "Erythropoietin", "aln": "MGVHECPAWLWLLLSLLSLPLGLPVLGAPPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQK-EAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTG--EACRTGDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2XNF5-1", "uniprot_id": "EPO_DANRE", "id": "Q2XNF5-1", "name": "Erythropoietin", "aln": "--MFHGSGLFALLLMVLEWTR--PGLSSPLRPICDLRVLDHFIKEAWDAEAAMRTCKDDCSIATNVTVPLTRVDFEVWEAMNIEEQAQEVQSGLHMLNEAIGSLQISNQTEV-----LQSHIDASIRNIASIRQVLRSLSIP----EYVPPTSSGEDKETQKISSISELFQVHVNFLRGKARLLLANAPVCRQGVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QCG3-1", "uniprot_id": "A0A8M9QCG3_DANRE", "id": "A0A8M9QCG3-1", "name": "Erythropoietin", "aln": "--MQTFSG-LVLVLMVFVC------LVSPLRPICDLRVLDHFVREAGDSEVIMRGCRGGCGVMKSYFVPLTRVDFAVWEHIDVQMQAVEVQTGLSVLLQALNTARKTVSNSS-----LLNTLENNISNLHSLGQIIRSLHLQQAESTVLPDDSAPASSQTQEVSSLPELLQVQSSFLRGKVRLLLSAAPACQRQNS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *:* :: * :* * *** ***:::: ** ::* * : . ** *:*:* .*: :.: ** ** ** :* :*: : .. * :: : .: *: ::* * * : .* .:: :*::* .***** :* . .*: ", "identical_positions": 44, "similar_positions": 49, "identity": "22.45%" }, { "cls_id": "homologset.agr.HGNC:3416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14753-1", "uniprot_id": "EPOR_MOUSE", "id": "P14753-1", "name": "Erythropoietin receptor", "aln": "MDKLRVPLWPRVGPLCLLLAGAAWAPSPSLPDPKFESKAALLASRGSEELLCFTQRLEDLVCFWEEAASSGMD-FNYSFSYQLEGESRKSCSLHQAPTVRGSVRFWCSLPTADTSSFVPLELQVTEASGSPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVVLRWLPPPGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVRARMAEPSFSGFWSAWSEPASLLTASDLDPLILTLSLILVLISLLLTVLALLSHRRTLQQKIWPGIPSPESEFEGLFTTHKGNFQLWLLQRDGCLWWSPGSSFPEDPPAHLEVLSEPRWAVTQAGDPGADDEGPLLEPVGSEHAQDTYLVLDKWLLPRTPCSENLSGPGGSVDPVTMDEASETSSCPSDLASKPRPEGTSPSSFEYTILDPSSQLLCPRALPPELPPTPPHLKYLYLVVSDSGISTDYSSGGSQGVHGDSSDGPYSHPYENSLVPDSEPLHPGYVACS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07303-1", "uniprot_id": "EPOR_RAT", "id": "Q07303-1", "name": "Erythropoietin receptor", "aln": "MDQLRVARWPRVSPLCLLLAGAAWASSPSLPDPKFESKAALLASRGSEELLCFTQRLEDLVCFWEEAANSGMG-FNYSFSYQLEGESRKSCRLHQAPTVRGSMRFWCSLPTADTSSFVPLELQVTEASGSPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVVLRWLPPPGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVRARMAEPSFSGFWSAWSEPASLLTASDLDPLILTLSLILVLISLLLTVLALLSHRRALRQKIWPGIPSPENEFEGLFTTHKGNFQLWLLQRDGCLWWSPSSPFPEDPPAHLEVLSERRWGVTQAGDAGAEDKGPLLEPVGSERAQDTYLVLDEWLLPRCPCSENLSGPGDSVDPATMDEGSETSSCPSDLASKPRPEGTSPSSFEYTILDPSSKLLCPRALPPELPPTPPHLKYLYLVVSDSGISTDYSSGGSQGVHGDSSDGPYSHPYENSLVPDTEPLRPSYVACS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19235-1", "uniprot_id": "EPOR_HUMAN", "id": "P19235-1", "name": "Erythropoietin receptor", "aln": "MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGLSDGPYSNPYENSLIPAAEPLPPSYVACS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* .. **:*..***********..*.**************:**.*******:*************.:*:. *********.*. * * ******.**::*******************:** ***:*****:************.**:** *:*..********** :***:************ **..****:************** ****************.*********.****.***************:* :************:*:***********.***************** *.******** :.*.***** ****** *.. ** :.*::*:**********:*********:***** * **:*.***.*** .:***.**:***.* ***** ***:*.:***********:** * :* *****************************.***.:*. ******:******:* :*** *.*****", "identical_positions": 401, "similar_positions": 76, "identity": "78.94%" }, { "cls_id": "homologset.agr.HGNC:3418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJ92-1", "uniprot_id": "A0A8I6GJ92_RAT", "id": "A0A8I6GJ92-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKE---NLLRVSESVVFTDTNSILRYLARVAATSGLYGSNLMEHTEIDHWLEFSATKLSSCDVLTSAIKELNHCLSLRTYLVGNSLTLADLCVWATLKGNAACQEHLRQSKTLVHVNRWYGFLEAQQAFRSVGTKWD---ASANKATGAPD-------RKQDIGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIEEGKAYVDDTPADEMKAEREQRIESRHRKNPVEKNLQMWEEMKRGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKLRALCKKVIDPVAPRYVALLKKEVIPVNILDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNPDGKITSLDAKLNLENKDYKKTTKITWLAETTQALPVP-AVCVTYEHLITKPVLGKDEDFKQYVNKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTKVEISK---KETGSAPKERPAAAVSAPCAAAEDAAILYS-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDAVRDLKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYRPGNPPTAAVQTVSTKSPSNTGEYT------------SLYNKVAAQGELVRKLKAEKAPKAKINDAVECLLSLKAEYKEKTGKEYVPGQLPAS--QNSHSSPVS----NAKPVGSETPEAKLLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATG-----------------------AEDKDKKKKEKENKSEKQNK--------------------------------------------------------------------------------------------------------PQKQNDGQGKDSSK-SQGSGLSSG----GAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQGALEKEKNHIADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTLEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPK-TPGEKQFAYQCSWGLTTRTIGVMIMVHGDNMGLVLPPRVASVQVVVIPCGITNTLSEEDREALMAKCNEYRRRLLGADIRARVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAESKLKGVLEDIQLNLFTRASEDLKSHMVVSDTLEDFQKVLDSGKVAQIPFCGEIDCEDWIKKTTARDQD-----VEPGAPSMGAKSLCIPFNPLCELQPGAMCVC--GKNPAKFYTLFGRSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGC7-1", "uniprot_id": "SYEP_MOUSE", "id": "Q8CGC7-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKE---NLLRVSETVAFTDVNSILRYLARIATTSGLYGTNLMEHTEIDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWD---VSGNRATVAPD-------KKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRTESKHRKNSVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFN-------KKVIDPVAPRYVALLKKEVVPVNVLDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWLAESTHALSIP-AVCVTYEHLITKPVLGKDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCREAPCILIYIPDGHTKEMPTSGSKEKTKVEISK---KETSSAPKERPAPAVSSTCATAEDSSVLYS-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDVVRELKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYKPGNPSAAAVQTVSTKSSSNTVEST------------SLYNKVAAQGEVVRKLKAEKAPKAKVTEAVECLLSLKAEYKEKTGKDYVPGQPPAS--QNSHSNPVS----NAQPAGAEKPEAKVLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATG-----------------------AEDKDKKKKEKENKSEKQNK--------------------------------------------------------------------------------------------------------PQKQNDGQGKDSSK-SQGSGLSSG----GAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPK-TPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLEKVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQD-----VEPGAPSMGAKSLCIPFNPLCELQPGAMCVC--GKNPAKFYTLFGRSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07814-1", "uniprot_id": "SYEP_HUMAN", "id": "P07814-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MATLSLTVNSGDPPLGALLAVEHVKDDVSISVEEGKE---NILHVSENVIFTDVNSILRYLARVATTAGLYGSNLMEHTEIDHWLEFSATKLSSCDSFTSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWFGFLEAQQAFQSVGTKWD---VSTTKARVAPE-------KKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFN-------KKVIDPVAPRYVALLKKEVIPVNVPEAQEEMKEVAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNLNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWLAETTHALPIP-VICVTYEHLITKPVLGKDEDFKQYVNKNSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVEATK---NETSAPFKERPTPSLNNNCTTSEDSLVLYN-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDVVRELKAKKAPKEDVDAAVKQLLSLKAEYKEKTGQEYKPGNPPAEIGQNISSNSSASILESK------------SLYDEVAAQGEVVRKLKAEKSPKAKINEAVECLLSLKAQYKEKTGKEYIPGQPPLS--QSSDSSPTR----NSEPAGLETPEAKVLFDKVASQGEVVRKLKTEKAPKDQVDIAVQELLQLKAQYKSLIGVEYKPVSATG-----------------------AEDKDKKKKEKENKSEKQNK--------------------------------------------------------------------------------------------------------PQKQNDGQRKDPSK-NQGGGLSSS----GAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPK-IPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQD-----LEPGAPSMGAKSLCIPFKPLCELQPGAKCVC--GKNPAKYYTLFGRSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARK1-1", "uniprot_id": "A0A8M3ARK1_DANRE", "id": "A0A8M3ARK1-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "-MALNLTFNSSNPPLGALLTAEHVKGSVNLSVEEGKD---TMLHVSDQVQFSDVNSITRYLARVAPALGLYGSNMMEQTEVDHWLEFSARRLCGQSDLSSALADLDKALALRTFLVGRSVTLADLCIWAALKGNGESQAKP---SSHPHLCRWFSFLSSQVPFSSVGSKWASKVSASKAASVEKD-------KKQDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTILRMGEKLLQEGKAYIDDTPPDIMKQEREQRAESRNRNNSVEKNMQMWEEMKKGTEFGQTCCMRAKIDMNSNNGCLRDPALFRCKNAAHPRTGTTYKVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVIEALGLRKPYIWEYARLNLNNTVLSKRKLTWFVDKGYVDGWDDPRFPTVRGVLRRGMTVDGLKQFIAAQGGSRSVVNMEWDKIWAFNKKLPVSCKKVIDPVAPRFTALLSSQVIPVCVSEAKETMKEVPKHPKNADVGLKQVWYGPKVFIEGADAETFTEGEIVTFINWGNIIITKIHRDSSGAILSLDGHLNLENTDYKKTTKITWLAESSRASFVP-TVCVNYQHLITKPVLGKDDDFKDYINKNSKIEEKMIGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCRESPCVLLYIPDGHTKEMPTAGSKDKSKSQPAKPVKAEPAPPSKAKSAPSSNPTPSAPGDASVILSNIMAQGDAVRQLKTEKAPKEQVDAAVKQLLALKSEFKQLTGQEYKPGMTLPASAPVQKSSAPTLAAAPGPASTGCPFTRVSEQGELVRKLKAEKAPKEQIDAAVKQLLAFKAEFKQLTGQDYKPGMAPPTASPPEPAPSSNSSPAGIYERVSEQGELVRKLKAEKAPKDQVDAAVKQLLALKAEYKQGTGQDYKPGVPTAKASPASSSSPAQLTVASTPAASAPSDSSPQAIYDRVSQQGDLVRKLKTEKAPKDQVDAAVKQLLNLKAEYKQQTGQEYKPGAPPSSGSATAQSNPTPPQSSSSQPQSSSSPQAQALFSDIAQQGEQVRRLKTEKAPKEQVDKAVKTLLELKGQYKALTGEEYKPVTTPGN----------------------SGGEDKSRKERENKSEKQGG--------------------------------------------------------------------------------------------------------GGGGGRKQQKGGEKPQQGQESGAG----GAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWDAIKEFFDREIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSRMFEIVFEDPK-KPGEKQLAYQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACLQVIIIPCGITATLPEAEKDLLLDQCSKYLSRLQKADIRVKADLRDNYSPGWKFNHWELKGVPIRFEVGPKDLKQGQFVAVRRDTGEKITVKEADAEKKIPNLLEEIQNNLFKRASDDLNKHMVVADTMEQFQKDLDQGRIVQIPFCGGIECEDWIKKTTAKDQD-----LEPGAPSMGAKSLCIPFKPLKNLQAGQMCVS--GKEPAQYYTLFGRSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38708-1", "uniprot_id": "YHI0_YEAST", "id": "P38708-1", "name": "Putative proline--tRNA ligase YHR020W", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVSEAFAKLCVNEKPPAESAVAVKSLV-----FKPKTPKSATP-VPIVVVALQSTTTPSALIANAT-----------------------------SSKDPRLARDDLVK------QAFQSESARAFILG---------------------DLANATSNFHLLIDHELGTVDGDTILQLNDSTYMKK------SDMMKFLNNFE------------------------------------------DSQKVVDFSQEVSKE--------------------------------------------------------------------------------------------------------TATEGKKQQK---K-QQPSKAGTA----AAAAAAALEDAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCYILRPPSYAIWENIQKWFDDKIKAIGVQNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPYYAKWVQSYRDLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHTAHLTAKDAEEEVLQILDFYAGVYEELLAVPVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPLGSDHPKIFAYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQRKHIHETARSVESRLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQVVVVRRNDSKKYVVSFDELEARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVMECEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPFDQP-VLNEGQKCIK--CERIAVNYCMFGRSY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P28668-1", "uniprot_id": "SYEP_DROME", "id": "P28668-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "-MSIKLKANLNNPPISGLATAHLINGTVPVEIVWSKEETSLQFPDNRLLVCHSNNDVLRALARAAPDYKLYGETAIERTQIDHWLSFS---LTCEDDISWALSFLDKSIAPVTYLVANKLTIADFALFNEMHSR---YEFLAAKGIPQHVQRWYDLITAQPLIQKVLQSLPEDAKVKRSPQSSKEQTPAKTGERKQEGKFVDLPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQYYALAFQGTLIMRFDDTNPAKETVEFENVILGDLEQLQIKPDVFTHTSNYFDLMLDYCVRLIKESKAYVDDTPPEQMKLEREQRVESANRSNSVEKNLSLWEEMVKGSEKGQKYCVRAKIDMSSPNGCMRDPTIYRCKNEPHPRTGTKYKVYPTYDFACPIVDAIENVTHTLRTTEYHDRDDQFYWFIDALKLRKPYIWSYSRLNMTNTVLSKRKLTWFVDSGLVDGWDDPRFPTVRGIIRRGMTVEGLKEFIIAQGSSKSVVFMNWDKIWAFN-------KKVIDPIAPRYTALEKEKRVIVNVAGAKVERIQVSVHPKDESLGKKTVLLGPRIYIDYVDAEALKEGENATFINWGNILIRKVNKDASGNITSVDAALNLENKDFKKTLKLTWLAVEDDPSAYPPTFCVYFDNIISKAVLGKDEDFKQFIGHKTRDEVPMLGDPELKKCKKGDIIQLQRRGFFKVDVAYAPPSGYTNVPSPIVLFSIPDGHTKDVPTSG--LKVNAPDAKATKKASSPVSSSGQASELDSQISQQGDLVRDLK-------------SKKAAKDQIDVAVKKLLALKADYKSATGKDWKPGQTSASSAPVPAASSSSAN-----------------------------------------------------------------------------DAVSVNASIVKQGDLVRDLKGKKASKPEIDAAVKTLLELKAQYKTLTGQDWKPGTVPTTAAPSASAAPSVGVNDSVA-----------QILSQITAQGDKVRELKSAKADKATVDAAVKTLLSLKADYKAATGSDWKPGTTAPAPAAAPVKVKQE-----KNPDPASVLTVNTLLNKIAQQGDKIRQLKSAKSEKSLVEAEVKLLLALKTDYKSLTGQEWKPGTVAPAPTTVNVIDLTGGDSGSDVGSVLSKIQAQGDKIRKLKSEKAAKNVIDPEVKTLLALKGEYKTLSGKDWTPDAKSEPAVVKKEASPVSMASPAKDELTQEINAQGEKVRAAKGNKAAKEVIDAEVAKLLALKAKYKEVTGTDFPVAGRGGGGGGGSAKKAPKEAQPKPAKPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDPE--TQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEE-----AEPGAPAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46655-1", "uniprot_id": "SYEC_YEAST", "id": "P46655-1", "name": "Glutamate--tRNA ligase, cytoplasmic", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSTLTINGKAPIVAYAELIAARIVNALAPNSIAIKLVDDKKAPAAKLDDATEDVFNKITSKFAAIFD-----------------NGDKEQVAKWVNLAQKELVIKNFAKLSQSLETLDSQLNLRTFILG---------------------GLKYSAADVACWGALRSNGMCGSIIKNKVDVNVSRWYTLLEMDPIFGEAHDFLSKSLLELKKSANVG----------------------------KKKETHKANFEIDLP--------------------------------------------------------------------------------------------------------DAKMGEVVTRFPPEPSGYLHIGHA----KAALLNQYFAQAYKGKLIIRFDDTNPSKEKEEFQDSILEDLDLLG--IKGDRITYSSDYFQEMYDYCVQMIKDGKAYCDDTPTEKMREERMDGVASAR-----RDRSVEENLRIFTEEMKNGTEEGLKNCVRAKIDYKALNKTLRDPVIYRCNLTPHHRTGSTWKIYPTYDFCVPIVDAIEGVTHALRTIEYRDRNAQYDWMLQALRLRKVHIWDFARINFVRTLLSKRKLQWMVDKDLVGNWDDPRFPTVRGVRRRGMT---VEGLRNFVLSQGPSRNVINLEWNLIWAFNKKVIDPIAPRHTAIVNPVKIHLEGSEAPQEPKIEMKPKHKK------NPAVGEKKVIYYKDIVVDKDDADVINVDEEVTLMDWGNVIITKKNDDGSMVAKLNLEGDFKKTKHKLTWLADTKDVVPVDLVDFDHLITKDRLEEDESFEDFLTPQTEFHTDAIADLNVKDMKIGDII---------------QFERKGYYRLDALPKDGKPYVFFTIPDGKSVNKYGAKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . .. * . . .: . . : * *. : . . : . :: :: . : . . * . : : * * : : .: : .::: *: * : . :: :* : : :.* :. *:. : . :: . :* .. .: .:: * *.: : . : : : . :. ..* :: : .:: **.. .** ::. * . :. ..: . .*. : : .. : * * : ..*.: : *: * .. :: * * : : : . * . ..: : . : : *: * .. . : : : * : . : . . :: : .: :* . : : : . :* . ", "identical_positions": 34, "similar_positions": 153, "identity": "1.84%" }, { "cls_id": "homologset.agr.HGNC:34187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJW9-1", "uniprot_id": "DJC25_RAT", "id": "Q5BJW9-1", "name": "DnaJ homolog subfamily C member 25", "aln": "MAARLAWR-RGPGAAGQRPWLLLAPLLLVPLLVRPAEALVEGLYCGTRDCYEVLGVSRSASKAEIARAYRQLARRYHPDRYRPEPGD-GPGGAPPSA-EAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISVFQYFSWWNSYNKSISYLATVPKYRIQATEIAKEQGLLKKAKEKGKNKKSKEEIRDEEENIIKNIIKSKIDIKGGYQKPQVRDLLLFQVLLAPVHLCSYIAWYCRWVYNFNIKGKEYGEEERLYIIRKSMKMSQSQFDSLEDHQKEMFLKRELWIKENYEVYKQEQEEELKKKLANDPRWKRYRRWMKNEGPGRLTFVDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ALW5-1", "uniprot_id": "DJC25_MOUSE", "id": "A2ALW5-1", "name": "DnaJ homolog subfamily C member 25", "aln": "MAARLALR-GGPGAAGQRPWLLLAPLLLVPLLARPAEALVEGLYCGTRDCYEVLGVSRSASKAEIARAYRQLARRYHPDRYRPEPGD-GPGGAPPSA-EAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISMFQYFSWWNSYNKAISYLATVPKYRIQATEIAKEQGLLKKAKEKGKNKKSKEEIRDEEENIIKNIIKSKIDIKGGYQKPQVRDLLLFQVILAPVHLCSYIAWYCRWIYNFNIKGKEYGEEERLYIIRKSMKMSQSQFDSLEDHQKEMFLKRELWIKENYEVYKQEQEEELKKKLANDPRWKRYRRWMKNEGPGRLTFVDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1X3-1", "uniprot_id": "DJC25_HUMAN", "id": "Q9H1X3-1", "name": "DnaJ homolog subfamily C member 25", "aln": "MGAPLLSPGWGAGAAGRRWWMLLAPLLPALLLVRPAGALVEGLYCGTRDCYEVLGVSRSAGKAEIARAYRQLARRYHPDRYRPQPGDEGPGRTPQSAEEAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISVFQFFSWWNSYNKAISYLATVPKYRIQATEIAKQQGLLKKAKEKGKNKKSKEEIRDEEENIIKNIIKSKIDIKGGYQKPQICDLLLFQIILAPFHLCSYIVWYCRWIYNFNIKGKEYGEEERLYIIRKSMKMSKSQFDSLEDHQKETFLKRELWIKENYEVYKQEQEEELKKKLANDPRWKRYRRWMKNEGPGRLTFVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYL9-1", "uniprot_id": "A0A8M1NYL9_DANRE", "id": "A0A8M1NYL9-1", "name": "DnaJ homolog subfamily C member 25", "aln": "MAASIELR------------LTLWICLVFILCFHSVSALIEGLYCGTQSCYDVLGVSRDVSKAELGRAYRQLARRYHPDRFQPGETD----DTQESAQQKFLLVATAYETLKDEELRKDYDYMLDHPEEYYSHYYTYYRRRLAPKVDVRIVILVTICAISLFQYYSWWSSYTEAINYLMTVPKYRIQATELAKQQGLLNRTKEKGKNRRSKEEIREEEEQIIRDIIKNKIDIKGGYQKPNVSDILLCKIVLFPYHLCTYVAWNFSWFYRFTIRGEEYGEEERLYIIRKYMKMSQAQFDSLENSLIETFLKQQLWIKENYEAYKKEQEEEMKMKMATDSRWKRYRRWMKSEGPGRITFADD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXT2-1", "uniprot_id": "DJC25_DROME", "id": "Q9VXT2-1", "name": "DnaJ homolog subfamily C member 25 homolog", "aln": "-MRTHGLR-----------------LVLLALLPTMALGLLEGLYCGKENCYDVLGVTRESSKSEIGKAYRQLARRYHPDLHRGAEAK-------AAAETQFKLVATAYEILRDEESRTDYDYMLDNPDAYYAHYYRYYRRRVAPKVDVRVVIVVVLTIVSVIQYYSGWQRYDSAIKYFATVPKYRNQALEIAR-DEIQEKIQKKGKNRMSKNDQRDELERIIRRVIEEKMDVKGGYAKPTLWDVLWVQLIICPYTILSFIVWHAQWFWRYTVMKQPYGREQKLYLIRRHLGMGQHQFEAQEDKLIEEYLHLKLWKRENFVAWKAEQEEEMKKKLAENPRYKAYRRYMKNHGPGRITFED-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .*:******...**:****:*. .*:*:.:************ .: . :* * ******* *:*** *.*******:*: **:*** ** **:*******:**:* : :*::*::* *. * .:*.*: ****** ** *:*: : : :: ::****: **:: *:* *.**: :*:.*:*:**** ** : *:* :::: * : :::.* *.:.:.: : **.*::**:**: : *.: **:: *: * :*: :** :**: .:* *****:* *:* :.*:* ***:**..****:** * ", "identical_positions": 152, "similar_positions": 102, "identity": "42.22%" }, { "cls_id": "homologset.agr.HGNC:3419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42567-1", "uniprot_id": "EPS15_MOUSE", "id": "P42567-1", "name": "Epidermal growth factor receptor substrate 15", "aln": "MAAAAQLSLTQLSSGNP-VYEKYYRQVEAGNTGRVLALDAAAFLKKSGLPDLILGKIWDLADTDGKGVLSKQEFFVALRLVACAQNGLEVSLSSLSLAVP--------PPRFHDSSSPLLTSGPSVAELPWAVKSEDKAKYDAIFDSLSPVDGFLSGDKVKPVLLNSKLPVEILGRVWELSDIDHDGKLDRDEFAVAMFLVYCALEK----EPVPMSLPPALVPPSKRK-------------------------------------------------------------------------------------TWVVSPAEKAKYDEIFLKTDKDMDGYVSG--LEVRETFLKTGLPSALLAHIWSLCDTKGCGKLSKDQFALAFHLINQKLIKGIDPPHSLTPEMIPPSDR---------------------------------------------------------------------------------------------------SSLQKNITGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTVKQR-------------------------------------------------------------------------------------TSEVQDLQDEVQRESINLQKLQAQKQQVQELLGELDEQKAQLEEQLQEVRKKCAEEAQLISSLKAEITSQESQISSYEEELLKAREELSRLQQETAQLEESVESGKAQLEPLQQHLQESQQEISSMQMR-LEMKDLETDNNQ-SNWSSSPQS----------------------------VLVNGATDYCS---------------------------LSTSSSETANFNEHAEGQNNLESEPTHQESSVRSSPEIAPSDVTDESEAVTVAGNEKVTP----------------RFDDDKHSKEEDPFN-------VESSSLTDAVADTN----------LDFFQSDPFVGSDPFK-------------DDPFGKID---PFGGDPFKGSDPFASDCFFKQTS-----------TDPFTTS----------------STDPFSASS---------------------------------------------------------------------NSSNTSVETWK--------------HNDPFAPGG--TVVAAASDSATDPFASVFGN-ESFGDGFADFSTLSKVN-----------------------NEDAFNPTISSSTSSVTIAKPMLEETASKSEDVPPALPPKVGTPTRPCPPPPGKRP-INKLDSSDPLKLNDPFQPFPGNDSPK-----EKDPDMFCDPFTSS-TTTNKEADPSNFANFSAYPSE-------------------EDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YC99-1", "uniprot_id": "A0A8I5YC99_RAT", "id": "A0A8I5YC99-1", "name": "Epidermal growth factor receptor substrate 15", "aln": "MAAAAQLSLTQLSSGNP-VYEKYYRQVEAGNTGRVLALDAAAFLKKSGLPDLILGKIWDLADTDGKGVLNKQEFFIALRLVACAQNGLEVSLSSLNLAVP--------PPRFHDSSSPLLTSGTSVAELPWAVKSEDKAKYDAIFDSLSPVDGFLSGDKVKPVLLNSKLPVEILGRVWELSDIDHDGKLDRDEFAVAMFLVYCALEK----EPVPMSLPPALVPPSKRKTVSISGSMWAIPSSAAKESYHSLPP-------------------------------------------------VGISPTKAPLRQWVVSPAEKAKYDEIFLKTDKDMDGYVSG--LEVRETFLKTGLPSTLLAHIWALCDTKNCGKLSKDQFALAFHLINQKLIKGIDPPHSLTPEMIPPSDK---------------------------------------------------------------------------------------------------SSLQKNTIGSSPVADFSAIKELDTLNNEIIDLQREKNNVEQDLKEKEDTVRQR-------------------------------------------------------------------------------------TTEAQDLQDEVQRESLNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAEITSQESQISTYEEELSKAREELSRLQQETAQLEESVESGKAQLEPLQQHLQDSQQEISSMQMR-LAMKDLETDNNQ-SNWCSSPQS----------------------------ILVNGAADYCS---------------------------LSTSSSETANLNEHAEGQNNLESEPIHPESSVRSSPEIAPSDVTDESEVVTAADIEKVSP----------------RFDDDKHSKEEDPFN-------VESSSLTDAVADTN----------LDFFQSDPFVGSDPFK-------------DDPFGKID---PFGGDPFKGSDPFASDCFFKQTS-----------TDPFATS----------------STDPFSASS---------------------------------------------------------------------NSSNTSVETWK--------------HNDPFAPGG--TVVAAT-DSATDPFASVFGN-ESFGDGFADFSTLSKVS-----------------------NEDPFNPTISSSASSVVIPKPVLEETPSKSEDVPPALPPKTGTPTRPCPPPPGKRP-INKLDSSDPFKLNDPFQPFPGNDSPK-----EKDPDMFCDPFTSSSTTANKEAEPSNFANFSAYPSE-------------------EDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42566-1", "uniprot_id": "EPS15_HUMAN", "id": "P42566-1", "name": "Epidermal growth factor receptor substrate 15", "aln": "MAAAAQLSLTQLSSGNP-VYEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVSLSSLNLAVP--------PPRFHDTSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEK----EPVPMSLPPALVPPSKRK-------------------------------------------------------------------------------------TWVVSPAEKAKYDEIFLKTDKDMDGFVSG--LEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPSDR---------------------------------------------------------------------------------------------------ASLQKNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQR-------------------------------------------------------------------------------------TSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ-LNWCSSPHS----------------------------ILVNGATDYCS---------------------------LSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVT-EKVCS----------------ELDNNRHSKEEDPFN-------VDSSSLTGPVADTN----------LDFFQSDPFVGSDPFK-------------DDPFGKID---PFGGDPFKGSDPFASDCFFRQS------------TDPFATS----------------STDPFSAAN---------------------------------------------------------------------NSSITSVETLK--------------HNDPFAPGG--TVVAAS-DSATDPFASVFGN-ESFGGGFADFSTLSKVN-----------------------NEDPFRSATSSSVSNVVITKNVFEETSVKSEDEPPALPPKIGTPTRPCPLPPGKRS-INKLDSPDPFKLNDPFQPFPGNDSPK-----EKDPEIFCDPFTSATTTTNKEADPSNFANFSAYPSE-------------------EDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B674-1", "uniprot_id": "A0ACD6B674_DANRE", "id": "A0ACD6B674-1", "name": "", "aln": "--MAASLSLTQLSSGNP-VYEKYYRQVDPSSSGHVGAGDAALFLKRSGLADLVLGKIWDLADSECKGSLNKQQFFVALRLVACAQNGLEVAYKSLNTAVP--------PPKFHDTSSPLQFG-PVPADTPWVVKAEEKVKFDAIFDSLSPVGGMLTGDKVKPVLLNSKLPVDVLGRVWELSDIDRDGMLDKDEFAVAMYLVYRALES----EMVPMSLPAALIPPSKRKPASSPPVMPLLPSPAQHKERNSAHSG------------------------------------------------SKTLPAKATPSQWVVSPADKAKYDDLFAKTDTDMDGLVSG--AEVRDIFLKTGLPSATLARIWELCDIGDVGKLTRDQFALALYLINQKLSKGIEPPQTLSPEMIPPPDR---------------------------------------------------------------------------------------------------LARQNNAV-TLQAADFSAIKELDSLTNEIMDLQKEKSVVEQDIKDREETIRQR-------------------------------------------------------------------------------------TSEVQDLQEEVQKGSDELGRLQAERQEVQEKLERLDEQKRSLEEQLTLIQQQCSQESQLIQSLQVQHSEQEQRISDYEEELTRAREELLHLQEETRQLGEKVQSARAQLCPLEDAVKESHTQIVQEQERLSELKMEEREVTARLTWKILEEP----------------------------VLVNGAAPSIEHPEPLQWPQPTAQPPETTKEDKVQDEEEQSSTDEPQELKVTEEEPGSEAEEPSSSPEQQESKPELYSYDLYNSAFSTISSTSVNWPQGNTE------NTTQEAEVDEERENTEERPATSTPKAETVEPEKRETAQPDTEPPSNPPSGPGLDFFQSDPFTDSDPFT-------------EDPFAKVDISDPFGGDPFKGTDPFAADNFFKQSSGSFPSRDPFSSSDPFNTTGPKEPDLFTSKTTNAVTPDPFASSSGNLQDTD-----------------------------------------------PFGSKMDALADSDPFSSSGTGPDPFGGS--DVVARDGPASANDPFAPGGT-TVVANSDPDKTDPFAAVFGN-ETFGGGFADFSSLAKSN-----------------------GNDPFDSSTN---------KNLFKEDTQS--DVPPALPPKTGTPTRPPPPPPGKRSNIHRSESSESFHRRGLFKAQGSAEFSS-----LPAKDSVPDPFAPS-SPHQAPCDPNRFASFDKYPTE-------------------EDMIEWAKRESEREERERVARLTQQEQEDLELAIALSKSELS---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W111-1", "uniprot_id": "Q9W111_DROME", "id": "Q9W111-1", "name": "", "aln": "----MNVDFARVCGKHIGVYEAYYKLIDPKGTGAIEAMTAAKFLKKSGLSDVVLSRIWDLSDPSGKGFLDKPGFFVALKLVSLSQAGQVASMANIYLDIANPPKLGELPKTMPSRIQTVPVASGGVANGDWSIGVIDRLKYEQLFESLHPSNGMLPGNKVKGVLMDSKLPMSILGTIWDLADQDKDGNLDMHEFVVAMHLVYQTLQK----RTIPSVLPPELRKPGGAGPPPKPAMPPPPAGAAMPRAPSGEGFGDGGFVANFPKDIAPPAAIPPLPVAVPPMTRIPPVGAVSSQPLIQTDPLIPIGAPVMANADWVVTPADLKRFEEIFRQSDLDKDGLVSG--LEVKDIFIKSGIPQRSLADIWALCDTNQSGKLTVEQFALAMWFVERKQ-RGVDPPHVLNANMVPPSMR---------------------------------------------------------------------------------------------------ATVAGVDLQPQEVKPTYSNPELEMISKEIEELARERRVLETEIAQKEADVRIK-------------------------------------------------------------------------------------NGEVRSLQSELDTLTATLKQLENQRGEAQKRLDDLQAQVSHNTAVLANVSLDISRTNEQVTKIRDQCHMQEVTINEQEGELNAKRSELQKLKDEEASLQKEYDSNNRELSKLTNHLQATQLQISSVRSMVTQLLETQRQMTDALLICRAAMENQNAELVSEYQLKIEPDFDEARKTLTKEVQLPKDDPFEENNSGAANQATNGFGSDPFSGQPVNKPAISTGFDDSFNMSSGFDSGFDAFGQSGAGSAFGQTQRDPFGSDAFAANKSNAITPEPGKDDFGSDPFAALHAPTGQGQVLSPNAQKSGPPPRPESPSPALPPKKSKVPPPRPAPPRAAQPTGGFGSGGGGGFADFDDFDNKLHHIPSAPSPSATALSPLPPTLPAPIPVVSGSSLLDSFTLFDDPGQIHKQAASTPNPTPITVPTVHTLLQTSLSTPAAPSPALASLSTSGSGSVAGAGADLPSSVTITTAPSLNNQHLSRSNTPLQNQRTADVKLETKAVVSVFDAFGEIGTRKAPTPSLITGPTDFKDDPFKDYRYEDPFSIKDPFAEEGEEELSEGKGADHKRNFAEDFSSGDEIGSAAKTLSNIVNNNSIKPKAATPLNNDLLQQFDAFNLNSSPAPSHHSGTSYHSNSKPSHDSQTALDAFADFDDFAATLATTGGSGAATTATTTGNTKLNNSFFDAFNDNFSVIQSSSVPTGVVRPNDQRAKAFDAFNDNFEDQFKTSPNANFAKFDGFEAHNFSSDFGNASFGTTGKEKQNGQVDKKFQSKEPVKDKFAADYSKPESFDADLEEALKRSVLDN--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39013-1", "uniprot_id": "END3_YEAST", "id": "P39013-1", "name": "Actin cytoskeleton-regulatory complex protein END3", "aln": "-------------------------------------------------------------------------------MP--------------------------------------------------KLEQFEIKKYWQIFSGLKPIENKVNHDQVLPILYNSKLDSSVLNKIWFLADIDDDDNLDFEEFVICMRLIFDMVNKN--ISSVPDELPDWLIPGSKVNLIKERKKRKQIENADLP-------------------------------------------------------------PKKEIKVDWYMSPDDLNQYEKIYNSCAKLTDGTITFNELSTKLSTKFFNISKTDLNKVWSLINPQNLPSIDRDPTFYFIHCLRQRNDLGAEIPASLPNSLAEVCNK---------------------------------------------------------------------------------------------------KQLS-----------------YDLRSSQPPTKRKEEANEVDNLRDNGQNSSSD-------------------------------------------------------------------------------------SSGSNVLSNEDSIKQKYASLTDDQVANMREQLEGLLNYKKSEKTQGGSKLSKRIN----IRSITDDLDNIEQQVEVLENYLNNKRHELQALQAEIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P34216-1", "uniprot_id": "EDE1_YEAST", "id": "P34216-1", "name": "EH domain-containing and endocytosis protein 1", "aln": "--MASITFRTPLSSQEQAFYNQKFHQLDTEDLGVVTGEAVRPLFASSGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMIAQLQNAPNQPISAALYESTPTQLASFSINQNPAPMQSGSATGNTNNTDIPALSSNDIAKFSQLFDRTAKGAQTVAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLIQLCMSHHPSMNTPPAVLPTQLWDSIRLEPVVVNQPNRTTPLSANSTGVSSLTRHSTISR-------------------------------------------LSTGAFSNAASDWSLSFEKKQQFDAIFDSLDKQHAGSLSS--AVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLEFAIAMFLIQKKN-AGVELPDVIPNELLQSPALGLYPPNPLPQQQSAPQIAIPSRASKPSLQDMPHQVSAPAVNTQPTVPQVLPQNSNNGSLNDLLALNPSFSSPSPTKAQTVVQNNTNNSFSYDNNNGQATLQQQQPQQPPPLTHSSSGLKKFTPTSNFGQSIIKEEPEEQEQLRESSDTFSAQPPPVPKHASSPVKRTASTTLPQVPNFSVFSMPAGAATSAATGAAVGAAVGAAALGASAFSRSSNNAFKNQDLFADGEASAQLSNATTEMANLSNQVNSLSKQASITNDKKSRATQELKRVTEMKNSIQIKLNNLRSTHDQNVKQTEQLEAQVLQVNKENETLAQQLAVSEANYHAAESKLNELTTDLQESQTKNAELKEQITNLNSMTASLQSQLNEKQQQVKQERSMVDVNSKQLELNQVTVAN----------------LQKEIDGLGEKISVYLTKQKELNDYQKTVEEQHAQLQAKYQDLSNKDTDLTDREKQLEERNRQIEEQENLYHQHVSKLQEMFDDLSQRKASFEKADQELKERNIEYAN-------NVRELSERQMNLAMGQLPEDAKDIIAKSASNTDTTTKEATSRGNVHEDTVSKFVETTVENSNLNVN-------RVKDDEEKTERTESDVFDRDVPTLGSQSDSENANTNNGTQSGNETANPNLTETLSDRFDGDLNEYGIPRSQSLTSSVANNAPQSVRDDVELPETLEERDTINNTANRDNTGNLSHIPGEWEATPATASTDVLSNETTEVIEDGSTTKRANSNEDGESVSSIQESPKISAQPKAKTINEEFPPIQELHIDESDSSSSDDDEFEDTREIPSATVKTLQTPYNAQPTSSLEIHTEQVIKYPAPG-------TSPSHNEGNSKKASTNSILPVKDEFDDEFAGLEQAAVEEDNGADSESEFENVANAGSMEQFETIDHKDLDDELQMNAFTGTLTSSSNPTIPKPQVQQQSTSDPAQVSNDEWDEIFAGFGNSKAEP--TKVATPSIPQQPIPLKNDPIVDASLSKGPIVNRGVATTPKSLAVEELSGMGFTEEEAHNALEKCNWDLEAATNFLLDSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *: :*. : ::. :: .::* . *. :* *.* * .. ** ** :.* *: :. * ** * * :: . ::: :: . * :: : . * :* * : .: : : :: * : * : .: .. :*. :: : . *..: . : : . : * : . .: : : . * . : : : ", "identical_positions": 29, "similar_positions": 78, "identity": "1.98%" }, { "cls_id": "homologset.agr.HGNC:3420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M3L7-1", "uniprot_id": "EPS8_RAT", "id": "F1M3L7-1", "name": "Epidermal growth factor receptor kinase substrate 8", "aln": "---------MNGHMSNHSSGYGIYPS-QMNGYGSSPPYSQMD-------REHCSRTSAKALYEQRKNYARDS----VSSVSDVSQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVAH---TCSYDSILALVCKEPTQNKPDLHLFQCDEVKANLISEDIESA-----ISDSKGGKQKRR----PEALRMIAKADPGIPPPPRAPAPVPP-------------------------GTVTQVDVRSRVAAWSAWAADQGDFEKPRQ-------YHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKSKKSKRKGPGEGVLTLRAKPPPPDEFVDCFQKFKHGFNLLAKLKSHIQNPSASDLVHFLFTPLNMVVQATGG----PELASSVLSPLLTKDTVDFLNYTVKAEERQLWMSLGETWMKVRAEWPKEQFIPPYVPRFRNGWEPPMLNFMGAPTEQDMYQLAESVANAAEQQRKQDSKRQSTEHSSMSDYPPADGYTFSNSMYHRGPHVDQGEAALALKSTPNRHVDRNYDP-VKTQPKKYAKSKYDFVARNSSELSVMKDDVLEILDDRKQWWKVRNASGDSGFVPNNILDIMRTPESGVGRTDPPYTHTIQ--------------------KQRTEYGPRS--ADTPSAPSPPPTPAPVPVPLPPS-------------------------APAPVPVPKVPANVTRQNSSSS---------ESGGSIARDSQRYKQLPVDRRKSQMEEVQDELFQRLTIGRSAAQRKFHVPRQNVPVINITYDSSPEEVKTWLQSKGFNPVTVSSLGVLNGAQLFSLNKDELRSVCP-EGARVFSQITVQKAALEDSSGSSELQEIMRRRQEKISAAAS-DSGVESFDEGSSH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08509-1", "uniprot_id": "EPS8_MOUSE", "id": "Q08509-1", "name": "Epidermal growth factor receptor kinase substrate 8", "aln": "---------MNGHMSNRSSGYGVYPS-QLNGYGSSPPYSQMD-------REHSSRTSAKALYEQRKNYARDS----VSSVSDVSQYRVEHLTTFVLDRKDAMITVEDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTISHCQAVVH---ACSYDSILALVCKEPTQSKPDLHLFQCDEVKANLISEDIESA-----ISDSKGGKQKRR----PEALRMIAKADPGIPPPPRAPAPVPP-------------------------GTVTQVDVRSRVAAWSAWAADQGDFEKPRQ-------YHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKSKKSKRKGPGEGVLTLRAKPPPPDEFVDCFQKFKHGFNLLAKLKSHIQNPSASDLVHFLFTPLNMVVQATGG----PELASSVLSPLLTKDTVDFLNYTATAEERKLWMSLGDSWVKVRAEWPKEQFIPPYVPRFRNGWEPPMLNFMGAPTEQDMYQLAESVAN-AEHQRKQDSKRLSTEHSNVSDYPPADGYAYSSSMYHRGPHADHGEAAMPFKSTPNHQVDRNYDA-VKTQPKKYAKSKYDFVARNSSELSVMKDDVLEILDDRRQWWKVRNASGDSGFVPNNILDIMRTPESGVGRADPPYTHTIQ--------------------KQRTEYGLRS--ADTPSAPSPPPTPAPVPVPLPPS-------------------------VPAPVSVPKVPANVTRQNSSSS---------DSGGSIVRDSQRYKQLPVDRRKSQMEEVQDELFQRLTIGRSAAQRKFHVPRQNVPVINITYDSSPEEVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRSVCP-EGARVFNQITVQKAALEDSNGSSELQEIMRRRQEKISAAAS-DSGVESFDEGSSH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12929-1", "uniprot_id": "EPS8_HUMAN", "id": "Q12929-1", "name": "Epidermal growth factor receptor kinase substrate 8", "aln": "---------MNGHISNHPSSFGMYPS-QMNGYGSSPTFSQTD-------REHGSKTSAKALYEQRKNYARDS----VSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMH---SCSYDSVLALVCKEPTQNKPDLHLFQCDEVKANLISEDIESA-----ISDSKGGKQKRR----PDALRMISNADPSIPPPPRAPAPAPP-------------------------GTVTQVDVRSRVAAWSAWAADQGDFEKPRQ-------YHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGG----PELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPYVPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEP-LKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADPPYTHTIQ--------------------KQRMEYGPRP--ADTPPAPSPPPTPAPVPVPLPPS-------------------------TPAPVPVSKVPANITRQNSSSS---------DSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCP-EGARVYSQITVQKAALEDSSGSSELQEIMRRRQEKISAAAS-DSGVESFDEGSSH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J5T6-1", "uniprot_id": "A0AC58J5T6_DANRE", "id": "A0AC58J5T6-1", "name": "Epidermal growth factor receptor kinase substrate 8-like protein 1", "aln": "-------------MDNRSGSVCVGQSPDMNGY--TPPASQMNGHGSLSPDVPGKKSSGKALYEQRKNYTKNS----INSLTDTSQYHVEHLTTFVMDRKEAMLTIEDGIRKLRLLDAKGKIWTQDMLLQVDNRAVSLIDHDSKNELENFPLGSIQHCQPVTN---ACSYDSILALVCKESGQGKPDLHLFQCEDIKASLIHMDIESA-----ISDHKGGKIKKR----PEVLKMILKSDGSIPPPPGGPAPQAP-------------------------AAVNQVDTKSRVASWSAWTNEQQDNDPQRH-------YTELDTPPEMSAAQVDRDVQILNHILDDIEHFVTKLQKAAEAFNELSKRKKSKKSKKKGPGEGVLTLRAKPPTQDEFIDCFQKFKHAFNLLGKLKNHIQNPSAVDLVHFLFNPLKLVIQTSGG----VDLAKSVVVPLLTREAIEFLHTAGSAEERHLWVTLGDAWTKCKLEWPKDYPFPSHTLSFRDGWEPPVL----VSREQDVTQLAERLNA-----AQSETPRPPITQQTVQDFSSADGYGLTHATHKRLHQLETDMAMAALKHAVSRHVDRNLDAHSRTAQRNFAKSKYDFVARNNTELSVLKDEVVEVLDDRKQWWKVRNGAGASGYVPNNILEISRAVD-MTGRGEPIYSHTIQLMMPKKEFELFKQLLGELNEKQRTDYVPRPTVTEAPPTPTPPPPPAPLLPTASPANQSAAAIIPANQSTGATSPANQRAVATSPANQSTAAADQANQSESNSGEQHDDTVSESDSVNMREQQRERAAPANRRKSNMEEVQDELMYRLTLGRSAQKRIQTPSRSSQPALSISYDSTPQQVKDWLMLKGFSAATVSSLGVLTGAQLFSLNKDELKTVCPDDGARVFSQISVQKAALERSSGS-ELMEVMRRRQEKLAATATSDSGVESFDEASSH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPW1-1", "uniprot_id": "Q8IPW1_DROME", "id": "Q8IPW1-1", "name": "", "aln": "MFKLLSSSFKRRSFRRRSKPVPGLGDTMVNHHSNGGGSAGNSSGSLRGGGAHGGGGGGGDYSGDDRSGGGEERERLESDLHDKPTYLLEHLATFTVNKESGIVYPADGMRRLLQLEKTTGIWSQKMQLCLDYQWVLIMDYETGNIIERFPASLVQEPTAFTSNDAMELYNNILVFIVSGGGGSRSEMHIFQSQSVSAVHLVEDLKQLRSGKMITQQRGATPTQSGGGGASSMAMMMSKTSSSSSHSRVELHQHREQRAERERERDRDRERESHHHMHQRSSMEQYGIRAGVGVSGDDVAHISGETDSEHGGIGGGGATERDETSSTSSEKYERDVAVLNHCFDDIEKFIARLQHAAAASRELERRRRNRKSKKRDPGEGLLTLRTRPPHEKEFVDIFAKFKLSFNLLAKLKAHIHDPNAPELVHFLFTPLALIVEASSDTYYESQLPARVVNPLLTREAINLLINCVTSKETELWRSLGDAWVIPRDQWKDD--VGSYHPVFLDGWSPDYL------INDELEPPPNS--------PPAHVSKRRLEVQAGSGLNGRGGGGYDDYDSGNGMNMAMGIEKYTIHHGNDGLRERERER---DRERAGAISASDFNARSELSFDSIE----------------GRGGGAAGHGHG------HGHG---------------------------------------------------------PGAGPTLSAITAG----------------------------LQNLHTRESRSGNGYGAG----------AGPGPSSELGGGGRGLPNVSDDQMLESWLEDLQATGAKIVLVTYPRTANNDKELSVMRGEYLEILDDTRKWWKARNMRGQVAHVPHTIVTPFNFGDG----------DGAQFYGQQQQPPTGPTGPGNKSRSGDNPGMEQRSPDPTDMMRSKHLGKKGEFRYF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:. . :* : : . .. : :. :. ..: * . * :***:**.::::..:: **:*:* *: . :*:*.* * :* : * ::* :: * :*.** . :.. .. *:.:*.:: . .:.::*:**.:.:.* : *::. *:: :*.. .: .. : *: . . .. . .:: * . :: *. . . . . .: * : ... : : :*** :*** :**** *:::**:** * **.:*::.:*.*::.****:****::** .**:* * *** .****.*** **::*.* :******.** ::::::.. :*. *: ***.::::::* ...* .** :** :* : :* .: . .: * :**.* * :::: .: . : . . .* . : . .:: . :*: : : * * ** **.. .:. :: ...* :*. . : * ..* . ... . : . :. . . . : * .. :*. ::* : . .. ..: * . ::.: * :.: .. .: . *. . :**:.:.* :. .... . : .*.. .: * . . : ", "identical_positions": 135, "similar_positions": 271, "identity": "14.2%" }, { "cls_id": "homologset.agr.HGNC:34211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JVF7-1", "uniprot_id": "A0A0G2JVF7_RAT", "id": "A0A0G2JVF7-1", "name": "", "aln": "MADSCRPGTPTAVPAVPTISTCSNGGCLRNTIHLPSSCQSRTWQLVTHQENRPTPDSAPVISEPVSCLATCFPETPCVGFVCRPIGSHTAGCASGPRGTPQSAASRQPSCLESASRHTMCCENSSSGQSSGQGSACTSAPCQTARDPPASCDDGSCQPSCSEVTSCAQTPCLPSSCETGSCQPT-YQGGPCQPPKGEGQPCQSVYYQPICYVLKSCQSAPCMPVSCQPVTCMCS-CGQTCCVPSPCQLLHCQPAPLISFICQPAAPCQFPCFAKNSSKSASC-VMISGQSICGEP-TPNQSGCESLSCHPPCCVTGVGKPSSSG--CCPPTSPDICQAGTCGPTS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A5X4-1", "uniprot_id": "KR291_MOUSE", "id": "A2A5X4-1", "name": "Keratin-associated protein 29-1", "aln": "MADSCCPENPTAVPTVPTISTCSNGGSIRNAIRLPSSCRCRTWQLVTHQENRQGPDSVPVSSEPVSCPSTCFPETPCVGFICQPIGSHMACCASDTGGSPHPAASCQPSCLESAGCHTMCYENSSCHQSSGQGSACTSGSCQTACGPSASCDDRSCQPSCSEATSYAETPCLPAGCEAGSCQPTSCQGGSHQPTRGEGQLCQSVYYQPICYVLKSCQSTPCMSVSCQPLTCMCF-CSQTCCVPPTCQPLHCQTTPIISFICQPVAPCQSPCFLKSSSKSASC-VMISGQQICGGP-TPDQSGCQSPSCHPPCCVTGLGQPSSSGPGCCPPTSPDICQAGTYGPTS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MX34-1", "uniprot_id": "KR291_HUMAN", "id": "A8MX34-1", "name": "Keratin-associated protein 29-1", "aln": "MADGCCPGNTTAIPAVPTITTYPVKGGFRHALCLPSSCHSRMWQLVTCQESCQPSIGAPSGCDPASCQPTRLPATSCVGFVCQPMCSHAACYQSGTGQSPCLVSSCQPSCSESTCCQEKCCDASPCQQSSCQESVCMSGSCQAACGQSVCCDAGSCQPSCSEVTSCPETSCLPTICTASPCQPTWCQGSSCQPVSGEGQPCKSTYYQPICYIFKPCQSALYMPVPCQPSTCVFSSCNTTCCVPSHCQPPHCQLVPSTCFIYQPVANCQAPCSTKNCCKPASCDTVISGQPTCDGPPSYNQSGCKS-----ACCVTGLGTSPSSGSNCLPTSCQPSCESSFCKATLC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* * ..**:*:****:* . * :*::: *****:.* ***** **. . ..* .:*.** .* :* *.****:*:*: ** * *.. :* .:* **** **: : * : *.. *** * *.* *..**:* . ...** ********.** .:*.***: * :..**** **.. ** **** *:*.*******::*.***: *.*.*** **: *. *****. ** *** .* .** **.* ** ** *...*.*** .:**** *. * : :****:* .*****:* ..*** * *.:. *::. .* ", "identical_positions": 164, "similar_positions": 89, "identity": "47.4%" }, { "cls_id": "homologset.agr.HGNC:34218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC-CGCCG---CGCGGCGGCGCGGCGGCGCGGCG------GCGCG----GCG-CGGCGCCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC-CGCCG---CGCCGCGGCGGCGCGGCGCGGCG------GCGCG----GCG-CGGCGCCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGC-GGCGG---CGCGGCG-CGCGGCGCGGCGSCG------GCGCG----GCG-CGGCGCCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG------------GCGGCGCGGCG----GCGGCG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCGCCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC----------GCGGCGCGGCGCGGCGCGGCG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCGCCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG-------------CGGCGCGGCG--GCGCGGCG-CGGCGCG-CGCGGCG------GCGCG----GCG-CGGCGCCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGCGCGGCG---CGCGGCG-CGGCGCGGCGCGGCG-------CGCG--GCGCG-CGGCGCCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEY9-1", "uniprot_id": "SCGR1_HUMAN", "id": "A0A286YEY9-1", "name": "Small cysteine and glycine repeat-containing protein 1", "aln": "MGCCGCGGCGGCGG------------CGGG----CG------GGCGRCTTCRCYRVGCCS----------------------SCCPCCR---GCCGGCCSTPVICCCRRTCSS--------CGYSCG--KGCCQQKCCCQKQCCC-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ********** *** * *** * * ** . . * ** **** ** ..*:***** *. *. .** ***********::* * ", "identical_positions": 55, "similar_positions": 10, "identity": "36.67%" }, { "cls_id": "homologset.agr.HGNC:34219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCGGCGGCGCGGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCCGCGGCGGCGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG----CGGCG----CGGCGG---CGCGGCG-CGGCGCG-CGCGGCGG------CGCG----GCG-CGGCG-CCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCG----CGGCG----CGCGGCG-CGGCGCGGCGCGGCG-------CGCGG--CGCG-CGGCG-CCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG---GCGGCG----CGGCG-----GCGGCG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC-GCGGCG----CGGCGCGG-CGCGGCG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCGG---CGGCG----CGGCGCG-CGGCGCG--GCGSCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DSO2-1", "uniprot_id": "SCGR9_HUMAN", "id": "P0DSO2-1", "name": "Small cysteine and glycine repeat-containing protein 9", "aln": "MGCCGCGSCG----------CS-----GGCG-------GGCG--GGCGGG---CGSCTT------CRCY----RVGCCSSCCPCCR---GCCGGCCSTPVICCCRRTCSS--------CGCGCG--KGCCQQKSCCQKQCCC-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****.** * *** *** * * * **.* * * * *..* ** **** ** ..*:***** *. *.**** *******.***::* * ", "identical_positions": 58, "similar_positions": 12, "identity": "39.46%" }, { "cls_id": "homologset.agr.HGNC:34220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCGG-CGGCGCGGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCCG-CGGCGGCGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG----CGGCG----CGGCGG---CGCGG-CG-CGGCGCG-CGCGGCGG------CGCG----GCG-CGGCG-CCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCG----CGGCG----CGCGG-CG-CGGCGCGGCGCGGCG-------CGCGG--CGCG-CGGCG-CCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG---GCGGCG----CGGCG-----GCGG-CG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC-GCGGCG----CGGCGCGG-CGCGG-CG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCGG---CGGCG----CGGCG-CG-CGGCGCG--GCGSCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YFB4-1", "uniprot_id": "SCGR2_HUMAN", "id": "A0A286YFB4-1", "name": "Small cysteine and glycine repeat-containing protein 2", "aln": "MGCCGCGGCGGCGG--RCGGCG-----GGCGGGCGGGCGGGCGGGCGGGCGGGCGGGCGG-----SCGSCTT-CRCYRVGCCSSCCPCCRGCCGGCCSTPVICCCRRTCHS--------CGCGCG--KGCCQQKCCCQKQCCC-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ********** * * *** * * ** *** *.** **. * * *. ** **** ** ..*:***** * *.**** ***********::* * ", "identical_positions": 65, "similar_positions": 9, "identity": "43.92%" }, { "cls_id": "homologset.agr.HGNC:34222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC--CGCCG---CGCGGCGGCGCGGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC--CGCCG---CGCCGCGGCGGCGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG------------GCGGCG-CGGCG----GCGGCG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC----------GCGGCG-CGGCGCGGCGCGGCG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG-------------CGGCG-CGGCGG--CGCGGCG-CGGCGCG-CGCGGCGG------CGCG----GCG-CGGCG-CCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGCG-CGGCG---CGCGGCG-CGGCGCGGCGCGGCG-------CGCGG--CGCG-CGGCG-CCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGCGGCGGCG---CGGCGCG-CGGCGCG--GCGSCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YF60-1", "uniprot_id": "SCGR3_HUMAN", "id": "A0A286YF60-1", "name": "Small cysteine and glycine repeat-containing protein 3", "aln": "MGCCGCGSCGGCGG-----------GCGGCG--GGCG------GGCG----GGCGG-VCGSCTT------CRCY----RVGCCSSCCPCCR---GCCGGCCSTPVICCCRR-TCRSCGCG-------CR--KGCCQQKCCCQKQCCC-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****.***** **** * ** *** *** **.* * * * *..* ** **** ** ..*:***** ******. * ***********::* * ", "identical_positions": 66, "similar_positions": 10, "identity": "43.42%" }, { "cls_id": "homologset.agr.HGNC:34223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCGGCGGCGCGGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCCGCGGCGGCGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG---GCGGCG----CGGCG-----GCGGCG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC-GCGGCG----CGGCGCGG-CGCGGCG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG----CGGCG----CGGCGG---CGCGGCG-CGGCGCG-CGCGGCGG------CGCG----GCG-CGGCG-CCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCG----CGGCG----CGCGGCG-CGGCGCGGCGCGGCG-------CGCGG--CGCG-CGGCG-CCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCGG---CGGCG----CGGCGCG-CGGCGCG--GCGSCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEV6-1", "uniprot_id": "SCGR4_HUMAN", "id": "A0A286YEV6-1", "name": "Small cysteine and glycine repeat-containing protein 4", "aln": "MGCCGCGSCGGCG-----GRCG-----GGCGG---GCSGGCGGGCGGGCGG-GCGSCTT------CRCY----RVGCCSSCCPCCR---GCCGGCCSTPVICCCRRTCGS--------CGCGYG--KGCCQQKCCCQKQCCC-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****.***** * *** *** *** ***.* * * * *..* ** **** ** ..*:***** * *.** * ***********::* * ", "identical_positions": 62, "similar_positions": 10, "identity": "42.18%" }, { "cls_id": "homologset.agr.HGNC:34225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC--CGCCG---CGCGGCGGCGCGGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC--CGCCG---CGCCGCGGCGGCGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG------------GCGGCG-CGGCG----GCGGCG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC----------GCGGCG-CGGCGCGGCGCGGCG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG-------------CGGCG-CGGCGG--CGCGGCG-CGGCGCG-CGCGGCGG------CGCG----GCG-CGGCG-CCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGCG-CGGCG---CGCGGCG-CGGCGCGGCGCGGCG-------CGCGG--CGCG-CGGCG-CCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGCGGCGGCG---CGGCGCG-CGGCGCG--GCGSCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YF77-1", "uniprot_id": "SCGR6_HUMAN", "id": "A0A286YF77-1", "name": "Small cysteine and glycine repeat-containing protein 6", "aln": "MGCCGCGGCGGG--------------CGGCG--GGCS------GGCG----GGCGG-GCGSCTT------CRCY----RVGCCSSCCPCCR---GCCGGCCSTPVICCCRR-TCHSCGCG-----CGCG--KGCCQQKGCCQQKGCCKKQCCC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******** **** * *. *** *** ***.* * * * *..* ** **** ** ..*:***** *:****. **** ******* ***** *** ", "identical_positions": 69, "similar_positions": 9, "identity": "45.1%" }, { "cls_id": "homologset.agr.HGNC:34226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC-CGCCG---CGCGGCGGCGCGGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGC-CGCCG---CGCCGCGGCGGCGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGC-GGCGG---CGCGGCG-CGCGGCGCGGCGSCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG------------GCGGCGCGGCG----GCGGCG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC----------GCGGCGCGGCGCGGCGCGGCG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG-------------CGGCGCGGCGG--CGCGGCG-CGGCGCG-CGCGGCGG------CGCG----GCG-CGGCG-CCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG------------CGGCGCGGCG---CGCGGCG-CGGCGCGGCGCGGCG-------CGCGG--CGCG-CGGCG-CCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YF01-1", "uniprot_id": "SCGR7_HUMAN", "id": "A0A286YF01-1", "name": "Small cysteine and glycine repeat-containing protein 7", "aln": "MGCCGCGSCGGCG--------------GGC--GGCG------GGCG----GGCG-GGCGSCTT------CRCY----RVGCCSSCCPCCR---GCCGGCCSTPVICCCRRTCGS--------CGCGCG--KGCCQQKGCCQKQCCC-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****.***** *** * * *** *** ***.* * * * *..* ** **** ** ..*:***** * *.**** ******* ***::* * ", "identical_positions": 63, "similar_positions": 10, "identity": "41.72%" }, { "cls_id": "homologset.agr.HGNC:34227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1Y7VJK9-1", "uniprot_id": "A0A1Y7VJK9_MOUSE", "id": "A0A1Y7VJK9-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCGGCGGCGCGGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIM3-1", "uniprot_id": "A0A1Y7VIM3_MOUSE", "id": "A0A1Y7VIM3-1", "name": "", "aln": "MG-CGCGGCGGCGDCSSCTTCRYYRCCGGCCGCCGCGCCGCGGCGGCGCGGCGCGGCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCRPTVVCCCRRCCCRSCGCG---CGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VIU2-1", "uniprot_id": "A0A1Y7VIU2_MOUSE", "id": "A0A1Y7VIU2-1", "name": "", "aln": "MGCCGCGGCGGCG----CGGCG----CGGCGG---CGCGGCG-CGGCGCG-CGCGGCGG------CGCG----GCG-CGGCG-CCG---GCCG-CCKPTVVCCCRRSCCRSCGCGSCGCSCGCG--KGCCQQKCCCQQKCGCKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJV2-1", "uniprot_id": "A0A1Y7VJV2_MOUSE", "id": "A0A1Y7VJV2-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCG----CGGCG----CGCGGCG-CGGCGCGGCGCGGCG-------CGCGG--CGCG-CGGCG-CCS---GCCG-CCKPTVVCCCRRTCCRSCGCDSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNY1-1", "uniprot_id": "A0A1Y7VNY1_MOUSE", "id": "A0A1Y7VNY1-1", "name": "", "aln": "MGCCGCGGCGGCG---GCGGCG----CGGCG-----GCGGCG-CGGCGCGGCGCGGCG----CGGCGCG----GCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQP5-1", "uniprot_id": "A0A087WQP5_MOUSE", "id": "A0A087WQP5-1", "name": "", "aln": "MGCCGCGGCGGCGGC-GCGGCG----CGGCGCGG-CGCGGCG-CGGCGCGGCGCGGCGGCGGCGGCGCGCGGCGCGGCGGCG-CCGGCCGCCG-CCKPTVVCCCRRSCCRSCGCGSCGCGCGCGCGKGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VP58-1", "uniprot_id": "A0A1Y7VP58_MOUSE", "id": "A0A1Y7VP58-1", "name": "", "aln": "MGCCGCGGCGGCGG---CGGCGG---CGGCG----CGGCGCG-CGGCGCG--GCGSCGG------CGCG----GCG-CGGCG-CCGGCCGCCG-CCKPTVVCCCRRTCCRSCGCGSCGCGCGCG--KGCCQQKCCCQQKCGCKKCCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YFG1-1", "uniprot_id": "SCGR8_HUMAN", "id": "A0A286YFG1-1", "name": "Small cysteine and glycine repeat-containing protein 8", "aln": "MGCCGCGGCGGG-----CGGCS-----GGCG-----GGCGGG-CGGGGCGG-GCGSCTT------CRCY----RVGCCSSCCPCCR---GCCGGCCSTPVICCCRRTCSS--------CGCGYG--KGCCQQKGCCQQKCCCQKQCCC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******** * * *** * * * ** *** ***.* * * * *..* ** **** ** ..*:***** *. *.** * ******* ****** *:* ", "identical_positions": 66, "similar_positions": 9, "identity": "44.59%" }, { "cls_id": "homologset.agr.HGNC:34228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1NGD4-1", "uniprot_id": "A0A8M1NGD4_DANRE", "id": "A0A8M1NGD4-1", "name": "", "aln": "------------------------------------------------MASLSE--ENFSCPICHEIFKDPVVLSCSHSFCRECLQQYWR-AVDIQECPVCRRRSSRDDPPNNLVLKNLCESFLKERKEKPSPGSEEICSLHGEKLKLFCLEDKQPVCLVCRDSEQHDNHKFRPIGEVVSSHKEELNTGLKSLQEKLRHKETIKEEFEKTVQHITAQADHSEHQIKQEFEKLHQFLKDREKGTITALRKEEKQKKQMMKEKLEEINTHISALSDSIRDTKEMLKANDVCFLKEFPGSMERVQISQPDPQTPSGALIHVSQYLGNLQYRVWRKMEDIVHYTPVILDPNTANSHIVLSEDLTSVRESENKQWLPDNPERFD-YPCVLGSVGFCSGKHRWDVEVKESRCWSVGVTTASNQRKRDVFFNTDV--WSVWH-------------------------------------------------------------DPYG-------LIKSSSNEFPVEQYLECVRVELDYDRGTVCFSDPVNNTHLHTFTTTFTDAVFP-FLWCDLFSSLRILPFNR---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TMD8-1", "uniprot_id": "A0AB32TMD8_DANRE", "id": "A0AB32TMD8-1", "name": "", "aln": "------------------------------------------------MASLKVSVEDISCSVCCEIFKDPVVLSCSHSFCRECLQQFWR-TKGTQECVVCRRRSSRDDPPNNLVLRNLCESFHQERKEKRSSGSEEMCSLHGEKLKLFCLKDKQPVCLVCVTSQQHDNHKFRPIGEVVPAYKEELYTALKTTQKKFEQNEEMKVEFEKTVQHITAQADDTEHQIKQQFEKLHQFLRDEEAATITALREEEEQKKQMMKEKLEEINTHNSALSDSIRDTKEMLEANDVCFLKEFAGSMERVQISQPDPQTPSGALIHVSQYLGNLQYRVWKKMQDVVHYTPVILDPNTAHPILVVSDDLTSVRETDVEHLFPDNPERFDWFPCVLGSEGFSSGKHSWDVEVKERRWWSVGVTTESNQRKGKVFFNTDV--WSVRYREDNQNVDDDDDADEEKDEDDDDDDEDDDDDDDDDDDDEDEDDDEEKDNEDDDDDDDDDDDDEDGDDDEDSSPNLSVSTSFNIEQDLECVRVELDYDRGTVCFSDPVTDTHLHTFTTTFTDTVFP-FFTS--LDPLRILPVKDQ--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UV72-1", "uniprot_id": "A0A8N7UV72_DANRE", "id": "A0A8N7UV72-1", "name": "", "aln": "------------------------------------------------MASLNVS-EDLSCPVCCEIFKNPVVLSCSHSVCKECLQQYWR-TKTTQECPVCRRRSSKGEPPVNLALKNLCELFLKERNERCSSASEEICSLHSEKLKLFCLEDKQPVCVMCVTLQQHDNHKFRPISEVASSYKEELNTALKSLQVKLKRNEERKAEFEKTVQHIKSQADHTERQVKHEFEKLHQFLRDEEEATITALREEEEQKKQMMKEKLEEMNTHISALSHTIKDTEEMLKAKDVCFLKEFPVSMERVQISQPDPQTPSGALIHVAGYLGNLTYRVWKKMQDIVHYTPVILDPNTAHPGLILSDDLTTLRNRRNTQPSPDNPERFDQMYCVLGSEGFISGKHCWDVEVKESLYWNFGVTTASNQRKG--FFSTGV--WSVRC-------------------------------------------------------------------------ELSFGSGFIVKQSLERVRVDLDCDRGTVSFSDPLKNTHLHTFTTTFTESVFPYFYFNDIVNCLKILPC-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B6D8-1", "uniprot_id": "A0ACD6B6D8_DANRE", "id": "A0ACD6B6D8-1", "name": "", "aln": "------------------------------------------------MSSLSE--EDLSCPVCREVFKNPVILSCSHSFCRECLQHFWR-TKGTQQCAVCRRISAH-EPLCNLVLKNVCESFIK--KEKP----EEICSLHNKKLKLFCLEDKQPVCLVCVTSHQHDQHTFRHIEEVLQAYKEELNKALTSLQEKLKHSKKLKGEFKRTVQHITAQADDTERQIKHQFEKLHQFLRDEEEATITALREEEEQKKQMMKEKLEEINTHISALSHTIRDTEEMLKANDVCFLKEFAGSMERVRISQPDPQTPSGALIHVSQYLGNLQYRVWRKMQDIVHYTPVILDPNTAHPHLIVSDDLTSVRLTEDKHPLPDNPERFDYFECVLGSVGFSSGKHRWDVEVKDNDEWTVGVTTAS-KRKGEDFYDSDI--WSVEN-------------------------------------------------------------VEYFANTPQDSPNSSASNCFHVKQDLEFVRVELDCDEGTVCFSDPVTNTHLHTFTATFTDSVFP-FFTS--LDPLRILPVKVSEHFTCNSGSSSFRHVSSCCPRLMSDQVTDVLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PZW6-1", "uniprot_id": "A0A8M1PZW6_DANRE", "id": "A0A8M1PZW6-1", "name": "", "aln": "------------------------------------------------MSSQAEY--DYICPVCHEVFRVPVILPCGHSFCQRCVRQFWS-GRRARECPVCRRSCRHLQPVVNLALKNLCEEFETRRKRSRP---EDMCGLHQEKLKLFCLQDNQPVCVVCFTSQQHDQHTLRPVAEAAAPRKDQLSAALKILQEKLQHREKTKEELQKTLQHIRAQAEQTERQIRLQFQKLHQFLRDEEEASVSAVREEEEEKQQMMKEKLEDINKHISDLSHAIRDTEESMSRSSIRFLQEFTVSMERVQISPPDPQIPAGALINESRHLGNLMHRVWRKMENIVQHTPVVLDPNTAHPDLLVSADLSSVRWSWSKRALPDNAERFDHHPCVLASEGVRSGTLSWAVEVRQSSDWTLGVTTELNQRKGWDFFSADV--WSVCY-------------------------------------------------------------DEYS-------VSERPVFGVRVKQRLERVRVDLDYDGGTISFSDAVNNTHIHTFSSNFTHTLIP-FFSCYTIFNLKILPSNSQQQLNTNAELTP---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TBF6-1", "uniprot_id": "A0A8N7TBF6_DANRE", "id": "A0A8N7TBF6-1", "name": "", "aln": "-----------------------------------------------MATKQSHLAEDLSCPICGSILQKPVVLFCRHRFCKPCLESLWN-GGGSCECPLCCQPSSMGELVVNTVLEKTCEGFLEKCKNDP-----LACREHGETLTLFCLEHLEPTCSKCKSSMNHQGHRLYPLNEASHDCKEELKNALKPLQEKLKLFRKVKLTCEHAVNHIKNQAENTERQIREEFEALHQFLRDEEASRLSMLKQEREQKRQMMNEKIEDLENDITSLTNTIRIIEQEMRSQDIPFLKNYKDTIKRTWRIPQDPEMIAGSLLDIAKHLGSLKFKVWERMLEIIQYTPVTLDPNTAASCFLLSEDLTTLQCCSQTFKLPENPERFNVGAEVLGYEGFSSGRHSWDVEVKNNTYWVIGVASASISRKGKHVLTPAEGFWTIRLR-----------------------------------------------------------NGEYK-------ACTAPWSPLTMTKEPQVVRVVLDMNRSRVTFYDLRERTPLFTYTDIITPRAFPYFCSACKEYPLKVLPAWISIKSE----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PZV1-1", "uniprot_id": "A0A8M1PZV1_DANRE", "id": "A0A8M1PZV1-1", "name": "", "aln": "MTLWRKELLSYAFSEVKVKGRNESVGYSVGFTVSSTVECLHWGLFTVMADALSFLEEDLSCLICCDVFTDPVTLKCSHSLCENCLKSFWK-TQDVLQCPVCRKECSPDEPTKSLAFRALCESFKTRKPTAVSG---DVCPQHKETLKLFCFEDKQPICVVCYTSKKHENHKCSPVEEAAGNLKADLKMQMDKLQVTLD---DLKKTHESCMEQAENIMEKEEIQIKKEFEKLHQFLKDEEDKWIKALKKQIKPQDGKFKARIKHLSTQITDLSERMAALWQDMEAENIPFLQNYSDTLQKLKHSSVE-KRPAEAEKYQHHSPQTMIFTTWARMQNLVEQPPVILDPNTASSKQWVSADCTSVQYVLKKVHMCDNP--KRLFLGVLASQGFNSGLHCWDVEVRDNNHWTLGVVGETVYRKRLYRMDPKSRFWCFRFVDG-----------------------------------------------------------KFK-------KGNNPGKAIDENKRPNIIRVQLDFEKGELRFIDPFRNKNLCTFTGGFPERVFPYFCSGDLATPLNIFPANKEKF------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3TL54-1", "uniprot_id": "TR43A_MOUSE", "id": "Q3TL54-1", "name": "Tripartite motif-containing protein 43A", "aln": "---------------------------------------------MESDNLQDPQEETLTCSICQSIFMNPVYLRCGHKFCEACLLLSQEDIKFPAYCPMCMQPFNQEYIN-DISLKKQVSIVRKKRLMKYLNSKEHKCVTHKAKKMIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWRRLKIQQNYVEIERRTTLWWLS-VKLREEVIKRVYGKQCPPLCEERDQHIECLRHQSNTTLEELRKSEATIVHERNQLIEVYRELMTMSQRPYQELLVQDLDDLFRRSKLAAKLDMPQGMIPRLHAHSIPGLTARLNSFRVKISFKHSIMFGYTSVRPFDIR-----LLHESTSLD------SAETHRVSWGKKSFSRGKYYWEVDLKDHEQWTVGVRKDPWLRGRSYAATPTDLFLLECLRKE----------------------------------------------------------DHYI------LITRIGG-EHYIEKPVGQVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFSAVYT-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86448-1", "uniprot_id": "TR43B_MOUSE", "id": "P86448-1", "name": "Tripartite motif-containing protein 43B", "aln": "---------------------------------------------MESDNLQDPQEETLTCSICQGIFMNPVYLKCGHKFCEACLLLFQEDIKFPAYCPMCMQPFNQEYIN-DISLKKQVSIVRKKRLMEYLNSEEHKCVTHKAKKMIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWRRLKIQQNYVEKERRTTLWWLKSMKLREEVIKRVYGKQCPPLSEERDQHIECLRHQSNTTLEELRKSEATIVHERNQLTEVYRELMTMSQRPYQELLVQDLDDLFRRSKLAAKLDMPQGMIPRLRAHSIPGLTARLNSFRVKISFKHSIMFGYTSLRPFDIR-----LLHESTSLD------SAETHRVSWGKKSFSRGKYYWEVDLKDYRRWTVGVCKDPWLRGRSYVATPTDLF-LECLRKD----------------------------------------------------------DHYI------LITRIGG-EHYIEKPVGQVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFSAVYT-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86449-1", "uniprot_id": "TR43C_MOUSE", "id": "P86449-1", "name": "Tripartite motif-containing protein 43C", "aln": "---------------------------------------------MESDNLQDPQEETLTCSICQGIFMDPVYLRCGHKFCETCLLLFQEDIKFPAYCPTCRQPCNQRYIN-DISLKKQVFIVRKKRLMEYLNSEEHKCVTHKAKKMIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWQRLKIQQNYVEKERRMTLWWLKSVKLREEVIKRVYGKQCPPLSEERDQHIECLRHQSNTTLEELRKSEATIVHERNQLTEVYQELMTMSQRPYQELLVQDLDDLFRRSKLAAKVDMPQGMIPRLRAHSIPGLTARLNSFRVKISFKHSIMFGYNSVRPFDIR-----LLHESTSLD------SAKTHRVSWGKKSFSRGKYYWEVDLKDYRRWTVGVCKDPWLRGRSYVVTPTDIFLLECLRNK----------------------------------------------------------DHYI------LITRIGR-EHYIEKPVGQVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFFAAYT-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLN6-1", "uniprot_id": "D3ZLN6_RAT", "id": "D3ZLN6-1", "name": "", "aln": "---------------------------------------------MESDNLQASQ-EILTCFICLGIFTDLVLTRCGHPFCRACLLLFSADTQIPIHCPLCRHPSKPNFRT-AIPGKKLISIVRKERIKKYLSSEEHKCMTHKERKTIFCDENRVLLCQLCSKSQEHRGHRHCHIEEAVLKQMEKLLKQMESLLKKIQELQENLEAEKTMTDQWMDYVTLREEMIRTEYRKLYPSLDEEEAQHIECMKNQGNTNLEELRKSEAMMVHKRSQLMKVYQELMTMSQKPY-EVLQQGLDDLFRRCELVQ-LGMPQVMKPELSAHPNAGLTARFSFFKVKIFFQNLIILNCKMSQFFDIRRFTSRPCHQNTSLD------SAGSYRASWGAMDFTTGKHYWELDLKDCEHWAVGVCSNVWLSRSHKKIGSSGAFLLVCVKEG----------------------------------------------------------NHYS------LFTTCPVSHHYIEKPTGRVGVFLDCEGGCMSFLDVAKSSLIHSYHPEAFSLRVRPFFSTVYTRS-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "I1YAP6-1", "uniprot_id": "TRI77_HUMAN", "id": "I1YAP6-1", "name": "Tripartite motif-containing protein 77", "aln": "---------------------------------------------MASAITQCST-SELTCSICTDYLTDPVTICCGHRFCSPCLCLLWEDTLTPNCCPVCREISQQMYFKRIIFAEKQVIPTRESVPCQLSSSAMLICRRHQEIKNLICETDRSLLCFLCSQSPRHATHKHYMTREADEYYRKKLLIQMKSIWKKKQKNQRNLNRETNIIGTWEVFINLRSMMISAEYPKVCQYLREEEQKHVESLAREGRIIFQQLKRSQTRMAKMGILLREMYEKLKEMSCKAD-VNLPQDLGDVMKRNEFLR-LAMPQPVNPQLSAWTITGVSERLNFFRVYITLDRKICSNHK-LLFEDLRHLQCSLDDTDMSCNP-----TSTQYTSSWGAQILSSGKHYWEVDVKDSCNWVIGLCREAWTKRNDMRLDSEGIFLLLCLKVD----------------------------------------------------------DHFS------LFSTSPLLPHYIPRPQGWLGVFLDYECGIVSFVNVAQSSLICSFLSRIFYFPLRPFICHGSK-------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* : * * * .* *: * * . . * * ::* * * .* * . .* : . : : * :.. : : .: . :. : * . * : : : : : . : . . * * ::::: * .*: . : : * ** : . : * : . : :: . * ", "identical_positions": 29, "similar_positions": 55, "identity": "4.75%" }, { "cls_id": "homologset.agr.HGNC:34229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D454-1", "uniprot_id": "CX049_MOUSE", "id": "Q9D454-1", "name": "Uncharacterized protein CXorf49 homolog", "aln": "MGSSEEQSVPGDD-----------------FYEESGDLNTGLSLVLRPAKSN----------------EGESSLSSPKGSKLTLVSQLEASENPSVVLWAGEYCPDSLVPEEERVGSPMDEKV-VGLDFLSQPSVETTATGQQVTNLETKGAREHPSPESVCAE--------TEAGSIRRAPQAS-EEAKFAASAGTFFPKGLEQSRSWVTPRKS--TTSRMVIGENVHHPTSE---------PEPLDELNEVQMMRVTICLKDGNHGNQAKNSGPAETGDLARHSNVQTRDSFMRMPSSLLVSTTRGLTSGVERQASKEPEPFSSKKKQGTLWGKGGSKSSYPEAAAGIG--------------------------------------------------ALPKASPRKKMAQKKKPLWDASAVTLGRAFHQWGQRLKSAPAEPATFPPISGVGLPGRSNKCSLLPLRPKQCKNLYTG----KRSGAKKTKELQLVAKEDTDSTRDPSSQ-------------------VQFPTHRAEPPCQSVHQ-EFNSGDINARSLQDAGNSQSSALNQRG---------IMSKKS-VLSGDQEEPVGLPAPDSE-ILQLPGTQGCPRCPELQKEIEDLRKQLSALQAVSEKFQTHLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR64-1", "uniprot_id": "CX049_RAT", "id": "Q3KR64-1", "name": "Uncharacterized protein CXorf49 homolog", "aln": "MGSPEEQSVPGDD-----------------FNEESTDPNKNLSLVSGPADSN----------------EGEIRLPSPKGSNLPLVSQQDTSEAPSVVLWTGGCWPDSLVSEEERLGSPEDEKM-DGLDFLSQPSVET---EQQVANPETPGAKEQPSSESFCAE--------TETGSNRRAPQASGSEEAKAASAATFLPKGLEQSRAWVSPRKS--TTSRMLISENVHHPPSE---------PELSEELNEVQMMRVTICLKDGNHGNQAKNSGPAETGDLARHSNVQTRESFMRMPSSLLT-TTRGLTSGMERQTSKELEPFSSKKKQGILWGKGGSKSNYAEAAAGVG--------------------------------------------------ALPKAGPRKKMTQKKKPLWDASAVTLGKAFHQWGQRLKSAPAEPATFPPISGVGLPGRSNKCSLLPLRPKQCKNFYTG----KRSGAKRTKELQLVAKEDTDSTRDPGSQ-------------------VQFPTCRAEPPCQSVHQ-EFSSGDINTRSLQDPGNSQSSGLSQRG---------ILSKKS-TPSGDQEEPVGPPAPDSE-ILQLHGTQGCPRCPELQKEIEDLRKQLSALQAVGEKFQTHST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1B0GR91-1", "uniprot_id": "A0A1B0GR91_MOUSE", "id": "A0A1B0GR91-1", "name": "", "aln": "MSSPDEVSFRGTN-----------------WGPESGEHTE-RRRFAHGFPRG---HGPGP------GPEEKVCLQVSRPPQYDSWLDREEMDGR-SVIWG----------CEGRPGTPVDDRG-DNLDFVQQLAIEGTSFGQHIANREAWGIHGHQSPPSCAAEPISI-WGDSDASTLRRSMRPQTSTEGKQVTATQLHPRGPGRGRAWMTPRRS--AMSRVVTSDDIQCPSSS---------PESSDEFSETQMMRVTICLKEG---NQPKSAGLTEQEDPARHTNVHGRESFVHVPPSMLASTPRGLGSAIEKQASGELESSSAKKKQTMVWSKEGGRPSHQGATAAAAAAATATASASASASATANATASASASASASATATATASTVAPAPVAVASAGLYKISPRKKPAQEKPSQWDTSRGPVARIFPPWGQRLKSATVEPATFPPISGVALLGKASKCS-LPSGPKEFKSVCTG----KKSIAKKTREPQAGPKEDN-SPRDPGLQ-------------------AQVPLHRAEQPSVCMHRGEMSSGDSNTRAPQVPANPQFF-LIQRC---------ARPRAPPAPAGDQELPLRLPFPVGDRQHQIQAIGGCQQCEMLQKEIDELKEQLAIMQVFKEKFQDP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ALN5-1", "uniprot_id": "A0A8I6ALN5_RAT", "id": "A0A8I6ALN5-1", "name": "", "aln": "MSSPDEASFRGTN-----------------LGPESGEPSE-RRRFPQGFARG---HGLGPEERLLRSREDKMCLPVSKTFPYDSWLDREEMEGR-SVIWG----------CEGRPGTPVDDRG-DSLDFVQHLAVEGTSFGQHLANREAWGVHRHPSPQTCAAEPFSI-WGDSDASMIRRGTRPLTSTEGKQFTASQLHPRALGRGRAWMTPRRS--ATSRMITSDDAQYPSSD---------PESSDEFSEIQMMRVTICLKEG---NQPKSTGLTELEDPARHTNVHGRENFVHVPSTLLATTPRGLSSAIEKQASGELESSLSKKKQSMVWGKEGSRPSHQGATAAAAATISASA----------------------------TASTAAPAPVAVASGGFPKTSPRKKPPSEKPSQWDASRGPVGRTFPPWGQRLKSAPVEPATFPPISGVALLGKASKCS-LPSGPKECKPFCTG----KKFMVKKSRETQAGPKEDNNSPRDPGLQ-------------------AQVPPHRAEQPSVCMYRGEMSSGDCNTRASQVPGNLQFLSLSQRC---------PRPRAP-APAGDQEIPLRLPFPVGDRQYPVQGVGGCQQCLMFQKEIDELKEQLGLALL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4Y8-1", "uniprot_id": "E9Q4Y8_MOUSE", "id": "E9Q4Y8-1", "name": "", "aln": "MSSLGKAAVPTACDDEDTLLTGDANSQHQVSGSEAGLSQEGRERLGDPVISPGVAEGPSPLQGPLEIREGEASLPGPESSDLGSGSKMEATEDTGSMLRD----------PEGGATSPVDQEEEVDMDFLPQLSIEAMTVMRELTNLQLRKVCRYPSPRTCAAELAAL-WGNVDEGSNRGALS-PSSVRGKQGPEGALYPRGLGRGRAWGTPRRH--TIGRMVSSEGVHYPSSN---------PVSSDEFSDTHVMKGTAGLKE----DQARSSGLTELDNIARHTNVRGRGNFVHIPPSVLSSATWGVSSGMERQASGEQESSLAKKKPNMVWGKEGSRPSHHGVTAAAA-----------------------------------TASAAAPASASTASGALPKTSPKKKQAQEKTSSSDVSRGYQGKNLPTWGQRLKSAFEGPTTLPPISGVALLGKASKCS-LPSGPKEFKSICTG----KKSIAKKTREPQAGPKEDN-SPRDPGLQ-------------------AQVPPHRAEQPSVCMYRGEMSRGDFNIRAPQVPANPQFFSLSQRC---------ARPRAPPAPAGEQNQLMDPIFPNEESQQVIHGTPGCAQCEMLQKEIDELKEQLAVMQALSETFQDP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M3X8-1", "uniprot_id": "F1M3X8_RAT", "id": "F1M3X8-1", "name": "", "aln": "MSSPDEAAVPAASEDKDSPPTGGMNFWDQVFVPEADLGQDSRKRLGNPVTSRRVPEGPSLFRGPLEIGEGEGSLPGPESSELESGAKLEATEERGGVLRD----------PECQTTSPIDQEE-VDLDFLPQLSNEAMTIMRELTNLQTRKVCRYPSPQTYAAELAAL-WENIDEGSNRRALS-LSSVKGKQAFEGAPYPRGLGRGRAWVTPRRG--TISRMVSSEVVQYPSSN---------TVSSDELSDTQVRKVTTCLKEG---DQARSSGLTELDNIGKHTTVHSRGNFVHVPPSVLSSATWGLSSGMERQASAELESSLFKKKPNMGRGKEGSRSSHQGATAAAA-----------------------------------TTSAAAPGSPSAASGALHKTSPKKKQVQEKNSSLDVSRGPQGRNLSPWGQRLKSAPVGLATLPPISGVALLGKASKCS-LPSGPKECKPFCTG----KKFMVKKSRETQAGPKEDNNSPRDPGLQ-------------------AQVPPHRAEQPSVCMYRGEMSSGDCNTRASQVPGNLQFLSLSQRC---------PRPRAP-APAGEEDAIVGAVLPGEERQQELQGTPGCAQCLMFQKEIDELKEQLGMAYP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MYA2-1", "uniprot_id": "CX049_HUMAN", "id": "A8MYA2-1", "name": "Uncharacterized protein CXorf49", "aln": "MSSPDKVSVCGAG-----------------FDLEGGKKAGSRTASPGAPGAHS----HGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWG----------REGRPGTPVDDQG-DVVDYSFYLADEPAAIVPPPS------VQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERG--SKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEG---SQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGA---------------------------------------------------LPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQG-------MSKKPQKPKHSSPG----KKPAGRKTRESQAAAREDNDPNRDEVPR-------------------AQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGG---------LVPRRH-APSGNQQPPVHP--PRPERQQQPPGAQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AG36-1", "uniprot_id": "A0A8I6AG36_RAT", "id": "A0A8I6AG36-1", "name": "", "aln": "MSCNKEGAVEEVS-----------------LDPEDGESPNVCLDVPCSPQDLS-------LDPDMGSHISKNEVETEDNSELDSGSKLQALESEMVVFEE----------HGEWSVSSARDKG-DLMDCLPLVSDNVEDKVQQPTDQMNQDARSRSSSKSCATQHSTT-WADTEADCSRRSMLGKRLGDVKRASVAPAHHWGPKGGRACRTKKKKKVTKSKKAIPEDIQDPPSD--------HDSSSDEYNEMQVMRVTICFKNG---EQIISGNSMAPEDKIRKRNVQLRGNFHHMTGSLQMSAPRGHILGMGKLG-----ASCSNRKASVFRGKEQSRPRYPGAAAGVLR----------------------------------------------------KASPKKKSAQEKKPLQDTPRVTGRKPVPLSGQRPKAAPVEIATFPPITCVPTLESSKKHP--TTTPLEATEPTHGNTSRKKAVAKNTRETLPVARGDRGLMCKDSMKKSTVLTPTSESYKVKEIAHAQVPPHRAEQPSVCMYRGEMSSGDCNTRASQVPANSQIVALNQG----------SASPRASVPYGDQDPSVAPPLPVGEKQHQTPGILGCQQCPLLEKEACRLRKQLAVMQALNKRFQNL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A668KLC8-1", "uniprot_id": "A0A668KLC8_MOUSE", "id": "A0A668KLC8-1", "name": "", "aln": "MSCNKEGAVEEVS-----------------LDPEDGEATNTCLDGPCSLQDLN-------LDPDMGSHISENEVKTEDNSEFDSGSKLQALESGMVDLQD----------HGEQPVSSARDEG-DLMDCLPPDSNKVEDKVQQPTDQMSQDVRSHSSPKSCATQQSTT-WADTVADCSRRNRLGKRLGDVKQASMAPVQHCGPKGGRACRTKKKKKVIKSKKTIPEDIQDPASD--------PDSSSDEYNEMHVMRVTICFKNG---GHIITGNAMAPEDKTRKRNVQLRGNFHHMTGSLRMSAPKGHMLGIGKLG-----ASCSNRKASVFRGKEQSRPPYPGAAVGVLR----------------------------------------------------KASPKKKSAQEKKPLQDIPRATGRRPVPLWGQRPKAAPVEVPTFPPINSVPTLESSKKH---DTTPLEATEFTHG-TSRKRAVAKNTRETLPVAREDRGLECKDTMKNSTVMTQTSESSKVKEIDHAQVPPHRAEQPSVCMHRGEMSSGDSNTRAPQVPADSQLVAPSQGGTGTSPSPSPSPSPRASAPHGDQDRSVVPPLPVGEKQHQAPGILGCQQCTLLEKEACRLRKQLAVIRALNKRFQNL--", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. : :. * : . : : : :. :. :* : : : . .:: . . *: . .: .: : *.:. :* .: : : :: : . : :: ..: : .: :. . :. * : :: .* :. .:.. : .::* * . . . : . *:* .:* .*:**:. * * : . * *: :.::* .: * . : .*.* *. * .: : *:. .* * *: * .. : . . *::: : * : . ** :* :::* * :**. ", "identical_positions": 40, "similar_positions": 121, "identity": "6.13%" }, { "cls_id": "homologset.agr.HGNC:3423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSY4-1", "uniprot_id": "D3ZSY4_RAT", "id": "D3ZSY4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TMQLLLALLGVLATFILTQLAEGTVP------------------------------------------------------------------------------------------APPSPVENSVLQDCIAEAKLLVDTAYNRTQKSIVQRLQSGSASPMDLLAYFKQPVAATRRVVQAADYMHVALGLLEEKLQPQESRP-------------FNVTDVLTEPQLRLLSQASGCALQDQVEKCS-----NKYRTITGRCNNRRRPWLGASNQALARWLPAEYEDHRSLPFGWTPGKRRNGFLLPLVRAVSNQIVRFPSKKLTSDQGRSLMFMQWGQFIDHDLDFTPESP-ARVTFNMGVDCEKTCA----QLPPCFPIKIPPNDPR------IKSQRDCIPFFRSAPACPQ--------NRNKVRNQINSLTSFVDASMVYGSEVSLALRLRNRTNYLGLLATNQQFQDNGRALLPFDNLHEDPCLLTN-RLVR------IPCFLAGDSRASETPKLAALHTLFVREHNRLATELKRLNPHWSGDKLYNEARKIVGAMVQIITYRDFLPLVLGKARMRRT--------LGPYRGYCSNVDPRVANVFT-LAFRFGHTMLQPFMFRLDSQYRTSAPNSHVLLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDSMLVDELRDKLFQQVRR--IGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNRNLARKFLNLYKTPDNIDIWVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKWG---VFTKRQRKALRRISLSRIVCDNTGISTVSR--DIFRANIYPQGFVSCSRIPKLNLSAWRGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49290-1", "uniprot_id": "PERE_MOUSE", "id": "P49290-1", "name": "Eosinophil peroxidase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQQLLALVGALATLILTQHAEGTAP------------------------------------------------------------------------------------------ASPSPVEISVLRDCIAEAKLLVDTAYNHTQKSIMQRLRSGSASPMDLLAYFKQPVAATRRVVQAADYMHVALGLLEERLQPRGSRP-------------FNATDVLTEPQLRLLSQASGCALQDQAERCS-----NKYRTITGRCNNKKHPWLGASNQALARWLPAEYEDHRSLPFGWTPGKRRNGFLLPLVRDVSNQIVRFPSKKLTSDRGRALMFMQWGQFIDHDLDFSPESP-ARVAFSMGVDCEKTCA----QLPPCFPIKIPRNDPR------IKNQRDCIPFFRSAPACPQ--------NRNKVRNQINALTSFVDASMVYGSEVTLALRLRNRTNFLGLLATNQRFQDNGRALLPFDNLHEDPCLLTN-RSAR------IPCFLAGDTRSSETPKLTALHTLFVREHNRLAAELRRLNPHWSGDKLYNEARKIVGAMVQIITYRDFLPLVLGRARIRRT--------LGPYRGYCSNVDPRVANVFT-LAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSVFFASWRIIHEGGIDPILRGLMATPAKLNRQDSMLVDELRDKLFQQVRR--IGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLRLYKTPDNIDIWVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKWG---VFTKRQRKALRRISLSRIVCDNTGITTVSR--DIFRANIYPQGFVSCSRIPKLNLSAWRGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11678-1", "uniprot_id": "PERE_HUMAN", "id": "P11678-1", "name": "Eosinophil peroxidase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHLLPALAGVLATLVLAQPCEGTDP------------------------------------------------------------------------------------------ASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGP-------------FNVTDVLTEPQLRLLSQASGCALRDQAERCS-----DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESP-ARVAFTAGVDCERTCA----QLPPCFPIKIPPNDPR------IKNQRDCIPFFRSAPSCPQ--------NKNRVRNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTN-RSAR------IPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKARARRT--------LGHYRGYCSNVDPRVANVFT-LAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRR--IGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRG---VFTKRQRKALSRISLSRIICDNTGITTVSR--DIFRANIYPRGFVNCSRIPRLNLSAWRGT----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P4H4-1", "uniprot_id": "A0A8M1P4H4_DANRE", "id": "A0A8M1P4H4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLPTFLFVVGCCCALSMGAEEESP------------------------------------------------------------------------------------------GRP------FILDSIEEAKKIVDAAYKYSRDESLARVRKDVIKPSDKLRLLKQPARKTREAVRAADYMAQTLRLISEKAHHVHKRS-------------INATNLLTQDELQTITRMTGCEAQTRPPSCRTTPLINKYRTASGVCNNRKNPLLGASNTPFARWLPAQYEDAVSQPKGWDPNKLYNGAALPMVRLVSNRILATADADIESDHDFTFMLTIFGQWVDHDLTFTPFSP-SIRSFSNGIDCENSCE----RSEPCFPISAPPGDQR------LRPN-TCLPVFRSAPTCGSGHTAYMFGEVPNVREQINTLTAYLDAGQVYGSEDGLAKELRDLTNDGGLLRVNNRFKDNGRELLPFTSVNTNLCATRQ-KILNDSTLTEVPCFIAGDARVNENPALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVGPDAYNRH--------LGPYPGYNENVDPTIANVFATAAFRFAHLTIQPFIFRLDENYKNHPQFPSVPLYEAFFSPWRVIFEGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSH--IALDLASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTELARKLIELYGTPENIDVWLGGVAEPFAPGGRVGSLFACLISRQFQKIRDGDRLWFESNG---VFTTKQKTALASVSLARIICDNTGILKVPR--DPFRFRS-PANFVNCGNIPAFDLEPWKETDRDSIPGPPGPRGPPGERGPQGVAGPPGPPGIPGPPINTTGQQSAFFASVNSILPATAKVVVFGQVLYNGQNHYNQTSGMFLCQIPGVYEFEFSCIGTRSLGFVTLKKNNRVELTPETVALNTRSLAEGKAVLSLQRGDRVYVEVSRSANGIGFSSYFSGHILFPV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ80-1", "uniprot_id": "Q9VJ80_DROME", "id": "Q9VJ80-1", "name": "", "aln": "MRKPEMLISLILWCLCASSLTLRIPEDLENAAINALSSERARSLTPCGSSAEAEGSVAGDYDVCPPSKYRQPTAECNNVSHRKWGARGDIFQRLLAADYADGVSQPRTSKGTHALPDAEVVIEQLQRHVEGELRHAHITAMLPAWGQLLANDLVEVGQLPISGKCCERDSAVKDPSELQHCFVRAGPDCKEYKRSAPGFDLEACQKHTRQQMNIASAYIDGSGLYGSTRHEFDQLRTYISGGVKVESCKYCQVAGATGALHRALLQQHNNIGERLSHINPDWSEEDVFLEARRIITATIQHITYNEFLPLVLGQETTAKEGLRLTAEKHSSNYSSSVRGGIYNEFATAAMPAFWSMYPPEMLAKKMSAHELLSIAALQKSLVPSQTNAEGWSELALAVHRGRDHGVASYVHALDLCERRFADQSAANVSFDTLAQVSNIPEEYITNLRDIYQNANDIDLLVGALLEEPVVGALFGPTISCLLSLQFEQLKQTDRFWYENEIPPSSFTLDQLKSIRQTTLSGLLCGSHQVSTAQSKAFILEDNYLNSILDCDQLPKFDLKPWQVNPEDEVHVEHVEVEPATKEAIAELSPELIEAAVERAKQELEERKRFEYEVWRTKGGISARSPDGTAASFSKANLAALNLANSSLIFELTSNEIVKTLNHITRRKRQIFNPNQNAFNRNELTDTLQTVDISGLLGGAQKQLDTCPEPSQQCDANSPFRTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPR----LTGVTGTALPNPRTISTTIHPDISN---LHTRYSLMVMQFAQFVDHDLTLTPIHKGFHESIPSCRPCNSRQT----VHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLPGQQS----------LGPRDQINQNTHFLDGSMVYGETTCLSNKLR------GFSGRMNSTQVRGKELLPLG--PHPECKSRNG-----------LCFLGGDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSWNAVNLYGLKLLP--QGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQPVEP--PLLLRDGFFRMDALLQPGIIDEILRGLVATP--METLDQFITGEVTNHLFEDRKIPFSGIDLIALNIQRARDHGIPSYNNYRALCNLKRATNWNDLSREIP-TEVINRFQKIYASVDDIDLFPGAMTERPLQGGLVGPTLACIIGIQFRQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENLEITGDMQRAAFDLPSNFLNPRVPCASMPQIDLNAWRENVQGCQIGNRNVR--------------VGESAFPSPCTSCVCSAEGAQCASLRITDCGQLIRQWPKEAILRDEVCNSQCGIYLTGQQASGFNPQQRQGQAQPRVTRSRNQNLFKFPDLTPFIASL------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01603-1", "uniprot_id": "PERO_DROME", "id": "Q01603-1", "name": "Peroxidase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIRARDLLLLALLGFISSALGLKVSSGYHIVHNQPQSSFPNYHGFSYLQGSAPYVIGNSLPTSPAPQNPFSSP----------------ASPPVSAYGYSFPTAGRVSCAAPPAVCEK----TAYRTLDGSCNHLEQPGLGVANSKYGRLLTPKYADGISAPT-----RSVTGDELPSARLVS---LVAFGEQDVPDPEFTLHNMQWGQIMTHDMSMQAGGTQSKKHPTRCCTDDGRLIGLDTAHKTCFAIIVPPHDPAY-----SQVGTECLNFVRTLTDRDSN-----CQYQGGPAEQLTVVTSYLDLSLVYGNSIQQNSDIREFQG-----GRMIVEERNGAKWLPLSRNVTGDCDAVD---------ASEVCYRSGDVRVNQNPGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYEWLPIFLGGENMLKNRLIYKAPSGSYINDFDPNIDPSVLNEHATAAFRYFHSQIEG---RLDLLSELRQVLGSLTLSDWFNRPGIIEVGDNFDSLTRGHATQPEELTDIN--FDRQIKHFLFRRNMP--FGSDLRSLDIQRNRDHGLASYNDMREFCGLRRAHSWEGYG-DLISPPILEKLKSLYPSHEDVDLTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGDRFFFENGDKLTGFTPDQLEELRKASMARLLCDNGNHISSMQP-EAFRTVSHSNPIIPCSNIPQVDLTKWIDQKLYATVDPSHYGKK--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : . . :: . : :. : . :** * **: ..* * : .* *..:* * * * .* ** * :* . . :: :.* : **: : . : * .: * * *: .*: . . :*:. * ::* . ***. :* : .* **: * : *: .** * .: * * ::* ::*****:. * :** :.. *::.**** * * : ::** .:. . .: . .* : * .: *** * :. **. . : * . * : . :* : ** * : : : : . ** . ** :*::** ***.:..** * :*.* . . . : : .:: :* : :::*: *. * *. .*. : *:: ** : * **::::. . ** * : ::::::*:* : : *. :* .:* * ", "identical_positions": 111, "similar_positions": 154, "identity": "7.41%" }, { "cls_id": "homologset.agr.HGNC:34236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB47-1", "uniprot_id": "D4AB47_RAT", "id": "D4AB47-1", "name": "", "aln": "MKVEGSPQRAKKTVGALEREKRQRAGPPEKGTTQRRDPAVRAERSSAAWTAGSRAQRAQRLSAKHSDPRSQRCSESPGLGTSTVLAHNARTSGSCARPAAMSESSRLCSGYYSLNRSFVEPFQCPRRGDGAALLYCCGFADLKYCCSEPGSYFPYKHSYMWSLSIGALIGLGIAALVLLAFVISVCVLCYLFLYTKPQRLDNGLKLQHLEASSTLEGNVNRKAKGLISNAASNSTNET-YEADDVTQERTMDTTQINIAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1Y9-1", "uniprot_id": "SHL2B_MOUSE", "id": "Q9D1Y9-1", "name": "Protein shisa-like-2B", "aln": "----------------------------------------------------------------------------------------------------MSQSSRLCSGYYSLNRSFVEPFQCPQRGDGAALLYCCGFADLKYCCSEPGSYFPYKHSYMWSLSIGALVGLGIAALVLLAFVISVCVLCYLFLYTKPQRLDNGLKLQHLETSSTLEGNINRKAKGLN--AVSNSTNETFYEADDGTQEKTMDITQINIAC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKW6-1", "uniprot_id": "SHL2B_HUMAN", "id": "A6NKW6-1", "name": "Protein shisa-like-2B", "aln": "----------------------------------------------------------------------------------------------------MSEASRLCSGYYSLNQSFVEPFQCPRRGEGAALQYCCGFADLKYCCSEPGSYFPYKHSYMWSLSIGALIGLGIAALVLLAFVISVCVLCYLFLYTKPQRLDTGLKLQHLEASSTQEGKSNGKTKALNSNAASNATNETYYEADDIIQEKTMDATQIHIAY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::***********:*********:**:**** **********************************:********************************.********:*** **: * *:*.* *.**:**** ***** **:*** ***:** ", "identical_positions": 133, "similar_positions": 15, "identity": "51.15%" }, { "cls_id": "homologset.agr.HGNC:34237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GM32-1", "uniprot_id": "A0A8I6GM32_RAT", "id": "A0A8I6GM32-1", "name": "", "aln": "---------MMSSVSTESKLQQ--AVSLKGVDPETCMIVFKNHWAQVVLAILQVVKILEKHDPLKNIQA-----------------KYGSIPPDEASAVQNYVEHMLFLLIEEQA-KDAAMGPILEFVVCENIMEKLFLWSLRR-EFTDETKLEQLKMYEMLVTQSYQPLLHHKPILKPLMMLLSSCSGTAT----PAVEGKLVVLLNQLCSILAKDPSILELFFHTSEDQG----------------AANFLIFSLLIPFIHREGTVGQQARDALLFIMSLSAENSMVANHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPALVQFMNSLEFCNAVIQVAHPLIRTQLVSYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHEN-VHILDTLTSRINTP-FRLCVVSLALFRTLIGLHCEDVMLQLVLRYLVPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCASGITLTLGNQERDYILWSKCMHDGSGPEEQPLPETPCSPSSPPPPPQPAPAACIVEYGKALDISYLQYLWEAHTNILHCMRDCRVWSALYDGDSPD--PETFLQSLSEESRENSSHPEARLSQQCIRTSG----QTKDKSQS----ELEWDDSYDTGISSGADVGSPGPYDDVETPA-PPAPIDPPKHIQEMKKNAILLFKGSYIEESDFQDDVMVYRLCAEKDAEDTREPQ------------------------------------------GATTDPPAEAQPKAQPEAQSLPTSNGPLFSPNPEAESKP--GRESSDLCQNMFSEAKPESEPGVALDSDSELTVPTFEAEPQSDSPVASTEGEDFIAQYDQIIQELDSGTEGLTEQSVPASEPSLLTHADEGRTECKAEE--------EEEDDDFDSLMADTPAEEAAPSPFGVGEDTATFTSRHPTRTQGTPFTGPFLSVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPVALTKDPIQEISRPESDKTLTDGPPRVLQPFLGNRAQMTKAPPNLPLPVKNTMLAAALFPEFLKELAALAQEHSILCYKILGDLEDSCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q505K2-1", "uniprot_id": "FHI1A_MOUSE", "id": "Q505K2-1", "name": "FHF complex subunit HOOK-interacting protein 1A", "aln": "---------MMSSVSTESKLQQ--AVSLKGVDPETCMIVFKNHWA-------QVVKILEKHDPLKNTQA-----------------KYGSIPPDEASAVQNYVEHMLFLLIEEQA-KDAAMGPILEFVVCENIMEKLFLWSLRR-EFTDETKLEQLKMYEMLVTQSYQPLLHHKPILKPLMMLLSSCSGTAT----PAVEGKLVVLLNQLCSILAKDPSILELFFHTSEDQG----------------AANFLIFSLLIPFIHREGTVGQQARDALLFIMSLSAENSMVANHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEDWHCILKDDWLLLPALVQFMNSLEFCNAVIQVAHPLIRTQLVSYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHRHEN-VHILDTLTSRINTP-FRLCVVSLALFRTLIGLHCEDVMLQLVLRYLVPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCASGITLTLGNQERDYILWSKCMHDGSGSEEQLLPETPCSPSSPSPPPPPAPAACIVEYGKALDISYLQYLWEAHTNILHCMRDCRVWSALYDGDSPD--PETFLQSLSEESRENSGHPEARLPQQSVRTSG----QTKDKSQS----ELEWDDSYDTGISSGADVGSPGPDDEVETPA-PPAPIDPPKHIQEMKKNAILLFKGSYIEESDFQDDVMVYRLCAEKDTEDTTEPQKDTSEPQGDTLEPLEDTSEQQEDTSEQLEDTSELQEDTAEPQGDTADPTAEAQPKLQPEAQSLPTSNGPLSSPDPETESQP--SRESSDLCQNTFSEAKPENEPGVALALDSELIATTFEAEPQSELAVVSTESEDFIAQYDQIIQELDSGTEGLTEQSIPISEPSLLTQQEERREECK-----------EEEDDDFDSLMAATPAVEAGSSPFGVGEDTA-FSSRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMAPAALTKDPIQEISRPESDKTLLDGPPRVLQPFLGNRAKVTRAPPNLPLPVKNTMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05DH4-1", "uniprot_id": "FHI1A_HUMAN", "id": "Q05DH4-1", "name": "FHF complex subunit HOOK-interacting protein 1A", "aln": "---------MMSSVSTESKLQQ--AVSLQGVDPETCMIVFKNHWA-------QVVKILEKHDPLKNTQA-----------------KYGSIPPDEASAVQNYVEHMLFLLIEEQA-KDAAMGPILEFVVSENIMEKLFLWSLRR-EFTDETKIEQLKMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTT----PTVEEKLVVLLNQLCSILAKDPSILELFFHTSEDQG----------------AANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHEN-VHILDTLTSRINTP-FRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFPEAFS------------ESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPD--PEMFLQSLTEEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQT----ELEWDDSYDTGISSGADVGSPGPYDDLEVSG-PPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQ------------------------------------------EEAARPPAEAQ----AEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPF-VGRDEAAFASRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRC5-1", "uniprot_id": "A0A8M9PRC5_DANRE", "id": "A0A8M9PRC5-1", "name": "", "aln": "---------MTSMVYNGNRGGQ--TLVLTGVDPETCMIVFKNHWA-------QVVKILEKHDPLRSNTGGLGGGHGLAGGGGLGSFRFGPIPGDEASAVQNYVEHMLFLLMEEECGQNGAMGPILEFVVMENVLERLFIWSLRR-EFTDDMKLEQLKMYEMLIGQARQPLLHHKPVLKPLMMLLSSCSGSPTGPSSPAVETELVLLLNQLCCVLAKDPSVLELFFHTSEDQG----------------AANFLIFSLLIPFIHREGSVGQQARDALLLIMALSAENHVVAKHIAENTYFCPVLATGLSGLYSSLPTKLDVPSEEWHCLHRDDWQQLPALVQFLNSLEFCNAVIQVAHPSIRDQLVGYIHNGFLVPVLAPALHKLTLEEVMTTTAYLDLFIRSVSEPALLHTFLSFILLHRHDS-VHILDTLVSRINTP-FQLGTVSLALFRTLIGLYCEDVMLQLIFKYLIPCNHMMLSQRRVLNERDCYSVSAAKILALTPSCCSPEIFPPP-LRQLDSILWSKGT-DGSQTGTMETKETLL-----------AEDDCVIGSEIYLDVSYLHYLYDARNSISHCMRACSVWSAPYNGENPP--PEEYQRSTLEEANRTRSSVATRKKTNSVHNSGP---PLKDLSATPGLLDLEWDDSYDA---CPAQVHTE---EDQETRH-IPD--EPPEHIQELRRTAIMFVKGSYIEESEFQNDVMVYNLVAQKDANDSGNNY---------------------------------------------RDPSKPTE----PEKQEVLDGR----TTDQKAKNSE-------SSINNGLNSPVNEMD--------------SKKRGLQSDHKLQGPEGEDLMAQYEELIRTLGAQPNSPTKADSELKSRVDLIDDEE-------------------DEMDFNSFSPETPEAEKLPSPFGTKPRSG-------SKGHAVPFTGPFVSVLLSRLENMPSNTLHVNLLLTGILAQLAAYPQPLLRSFLLNTNLVFQPSVRSLYQVLASVKNQIDVWSSKNKDSSELLTAAQHCLLARESS--------LRDPQSSQAEDASEADRIK------------RNSAIQPKTVVPLS-KTEVYATVLFAEFLKELAAIAQEHSILSHLPTEQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQK0-1", "uniprot_id": "U518_DROME", "id": "Q9VQK0-1", "name": "FHIP family protein CG3558", "aln": "MWLRQSSGGGVASVGHVGPLRQRPIDAATDCDPRACYDSFCKHWQ-------QAFEIIQHSAPPSHDDVLG----------------VVSHLDYMVTLLLVELHHCNKVSLPAAEASGPPAAPCLEFLLSENLLDKLYEWACTTGRYANAVRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFP---PDLEKRLVILLNQLCVVLMQNVHLLDLFFFSAQTQVQEQILNGNVAPPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNSNIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEISSIDWHRITPDDVTEIPELTLFMNALEFCNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTNIDSQISAMSYLDLILRSITEPGLLRAFVRFLLDTEKFDGERILDALVERLNSPDANLCMVTMALFDTLLGLHCEDLMLELLLKFMLPGKHVPISHRHKINKIDPYLNSSEFFLELSPDVMKRARDLARPKSVHEPVVSELTPLPSLPSPVMSKTIGAN------------WNYYGVHTGDSLYANIQAYLFEAHWRIAQCQKDCLKWANSYRYQKWPRHGQGRVHAHALELARQFFSEFGGGPIAANETGEKQLDSLQSIGESSGYESFKWRPADEESEATDTTVATTASEADMDHNSSSLSSVLGASGKRESWRTSNSNRNELILTDLDFSEDLFAQGTVSLGPFLNAIWGK-------------------------------------------LQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIAITSDTPSFHQVLRILKQQID--------------AELPVTEDSLEIIDVARSSLIDREFRLANARKGNEGSPMHHSQQQQMVTNSGQQQG------------------QLRSAYATLSAATPVQATPTSAYDPFKRSD------NKRRSISKSITSMFSRKSASTSTAPPNGSSASSGLSQIYAFFTGAASNLVGNNASNDGRGISQAQTSAGTCETSLSTQPPAGASRTGANATSTAASGSNSSIAGSTLTLSAQSNTTTHSASTLHGLDGGPSTGGFNSEPASLDSVASMGIIASTSGTERSRDLALCAVLMDEWLKELAAIAQEQSVVLVTEQGSL-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * . **.:* * :** *..:*::: * . .: : :.* : : .. . .* ***:: **::::*: *: .::: ::****:**:*: :: : ** *:*.*:**: :*:*..* * :* .**:****** :* :: :*:***.::: * ::**:*******::****::*:*******: *:** :* :. :*.: : :**:*.***.**** **..:: . :** : ** :* *. *:*:*******:**** *: **:.::::**:****.**: : .::. ::: :****::**::**.**. *: *:* .: . :***:*..*:*:* .* *::*** **:**:***:**:*::::::* :*: :*:* ::: * * *: :* *:* . : :: . . : * . **::*: * :* : * *: * :. : :: * .. :. . : .::* : : : * : : : .. :* :.: : : : :*.:*::. : : .. . . :. : : : ... ..:: : .: . . . . . . : : :: . * .*.: : .:.* : .. * .. * * : ::. .. *: . * . :. : * :*:..: :* . : . . . . . . . : .:.*: *:******:***:*:: . ", "identical_positions": 204, "similar_positions": 287, "identity": "17.51%" }, { "cls_id": "homologset.agr.HGNC:3424", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EBA0-1", "uniprot_id": "ERAL1_RAT", "id": "Q5EBA0-1", "name": "GTPase Era, mitochondrial", "aln": "MAAPRRYFPGIVRALLGAWQVGSHAGREWVSPPGSLLGNHVRCVSCVVGATFSGPLLASASSRYGQDSALDRILG-FPQPDSSLVPCVPAVSVHRDEQNLLLVHTPDMPENPRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSKKVHTTRCQALGVITEKETQVILLDTPGIISPVKQKRHHLELSLLEDPWKSMESADLVVVLVDVSDKWTRSRLSPQVLQCLTKFSQVPSILVLNKVDCLKQKSVLLELTAALTEGVVNGKMLNVRQAFR------------SRPSTHCPGPETEDPNTHAVRSPQRTG-WPYFQEIFMLSALNNKDVNTLKQYLLTQAQPGPWEFHSGVLTSQTPEEICANKIREKLLEYLPEEVPYSVQQKTVIWEEGPSGELVIQQNLLVPKESHVRILIGQKGLLISQIAQEVSQDLMDIFLCDVLLRLSVKLLK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZU4-1", "uniprot_id": "ERAL1_MOUSE", "id": "Q9CZU4-1", "name": "GTPase Era, mitochondrial", "aln": "MAAPRRYCAGLVRALLGARQVGSHAGREWLAPPGCLLGNQARCVSCVVGSTFSGPLLASASSRYGQDSALDRILG-FSQPDSSLVPSVPAVSVHRDEQNLLLVHTPDMPENPRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSKKVHTTRCQALGVITEKETQVILLDTPGIISPVKQKRHHLERSLLEDPWTSMESADLVVVLVDVSDKWTRSRLNPQVLQCLTKFSQVPSILVLNKVDCLKQKSVLLELTAALTEGVVNGKKLNIKQALR------------SRSSTHCPGPETEGPNAHSVRNPQRIG-WPYFQEIFMLSALNNKDVNTLKQYLLTQAQPGPWEFHSGVLTSQTPEEICANKIREKLLEYLPEEVPYGVQQKTVIWEEGPSGELVIQQNLLVPKESHVRILIGQKGLLISQIAQEVGRDLMDIFHCDVLIRLSVKLLK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75616-1", "uniprot_id": "ERAL1_HUMAN", "id": "O75616-1", "name": "GTPase Era, mitochondrial", "aln": "MAAPSWRGARLVQSVLRVWQVGPHVARERVIPFSSLLGFQRRCVSCVAGSAFSGPRLASASRSNGQGSALDHFLG-FSQPDSSVTPCVPAVSMNRDEQDVLLVHHPDMPENSRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSRKVHTTRCQALGVITEKETQVILLDTPGIISPGKQKRHHLELSLLEDPWKSMESADLVVVLVDVSDKWTRNQLSPQLLRCLTKYSQIPSVLVMNKVDCLKQKSVLLELTAALTEGVVNGKKLKMRQAFH------------SHPGTHCPSPAVKDPNTQSVGNPQRIG-WPHFKEIFMLSALSQEDVKTLKQYLLTQAQPGPWEYHSAVLTSQTPEEICANIIREKLLEHLPQEVPYNVQQKTAVWEEGPGGELVIQQKLLVPKESYVKLLIGPKGHVISQIAQEAGHDLMDIFLCDVDIRLSVKLLK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6U7-1", "uniprot_id": "ERAL1_DANRE", "id": "B0S6U7-1", "name": "GTPase Era, mitochondrial", "aln": "-MTLRSCETFLRRSLRFSTALNLTAFPEHEQLY---LRVSSGCSVFRPQTVRKCLFHWTPACTVSQGVFLDRLQKGAAVTDESLCNQPVSVSPDRAQQFSLLMKDPDQPENAKSLKVAIVGSPNAGKSTLTNQLLGRKLFAVSSKVHTTRSRAVGVLTENDTQIVLLDTPGLTTQIKAKRHQLENSLLVDPFKSLKEADLVVVLVDVSDKWTRSKLSYEVLKCLALNPDVPAVLVLNKVDLLKNKALLLDITAQLTEGMVNGKKIRIHGASKPVRKAAAGANSRLKEKKAAGSLEDEADHEDKLKALKSHGGWPHFKDVFMLSSIDHEDVETLKRYLFVAAKPCQWQYHSEVLTDQSPEDVCFNTIREKLLQNLPKEVPYTMTQEIEVWKESEDGVLDISIKLYVQKETHMKMVIGPGGQLITRINQEAGNDLMKIFLCNVRLKISVKLRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG07-1", "uniprot_id": "Q9VG07_DROME", "id": "Q9VG07-1", "name": "GTPase Era, mitochondrial", "aln": "---------------------------------------------MRYNLLASSLKLLNSTKTHNLFLVNVRSLTGAAHTNDAVAPTTRPPPAE----------SRNPGEEQRSLHIAVIGVPNVGKSTFINNTVNHRVCPTSAKVHTTRQSNTAIYTTGQTQLVFYDTPGLVTQHEIRRHHLDQNFKSAYRHAIQHADIIAVVHDASNAWTRKELHPTVLDTLKAYSNLPSFLVLNKIDALKSKRLLLDLIKTLTNDTLTVGKR---------------------------EVQAKSALAKEIRINKRESSWSHFSDVFLVSALTGNGLQEMQNYLVGQAKPRDWKYPADIHTDSSPEALIVESVRARLLDYLPQEIPYNLKCEIEYYSVEKN-VVYTSVQVQCPTTRIERLICGEGNGKLRQITERVTSDLVEMFGQAVSLTISTVSKGKKTAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..: . : . .:.:: . . . : *: : *::.::* **.****: *: :.::: ..* ****** .: * :**::: ****: : : :**:*: .: ::: **::.*: *.*: ***..* :* * .::*:.**:**:* **.* :**:: **:. :. : . : : . *.:*.::*::*:: :.:: ::.**. *:* *:: : : *..:** : : :* :**: **:*:** : : :. . : . :: . ::: * . : :* :.. **:.:* * : :*. ", "identical_positions": 78, "similar_positions": 136, "identity": "17.11%" }, { "cls_id": "homologset.agr.HGNC:34242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AEA7-1", "uniprot_id": "A0A8I6AEA7_RAT", "id": "A0A8I6AEA7-1", "name": "Ciliary microtubule inner protein 2B", "aln": "MAMVN-TFIPGLSPQNPHYIPGAKAGGRDTQAEGSGVRVPGLGRSSCSDHTGPVPSRYTGHCPLLRFSVGQTYGQVTGQLLRGPPGLAWPPAHRTLLPPIR-SPRSPVISRRRPP-PRRGHER--LSSSVVPGYTGFIP------QARFIFAKNCNQVWAEAMSDFTQRRGA--------QESPELQE-AKGEE---EVERDQGPEAE---EPQLKHELA-----------QTSPYSMDDTDPQKFFMSGFTGYVPRARFLFGSSFPVLTNQALQEFGQMCSGG--------RVQKDPKPLSPLP---RPNFQNLGLLPHYGGYVPGYKFQFGGTFGHLTHDALGLSITQKQLLA-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AIP0-1", "uniprot_id": "CMI2B_MOUSE", "id": "A2AIP0-1", "name": "Ciliary microtubule inner protein 2B", "aln": "MAVVN-TSIPGLSGENPHYIPG-----------------------------------YTGHCPLLRFSMGQTYGQVTGQLLRGPPGLAWPPAHRTLLPPIQ-SPRSPVISKGRLP-PRRGHER--LSSSIIPGYTGFIP------RAQFIFAKNCNQVWAEAMSEFTRRHGE--------QESHQLPDGAKGER---EVEEDQLREAE---EPPLKQELA-----------HASPYSMDDTDPHKFFMSGFTGYVPRARFLFGSSFPVLTNQALQEFGQMCSRG--------RAHKDPKPLSPLP---RPTFQNLGLLPHYGGYVPGYKFQFGGTFGHLTHDALGLSITQKQLPA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MTA8-1", "uniprot_id": "CMI2B_HUMAN", "id": "A8MTA8-1", "name": "Ciliary microtubule inner protein 2B", "aln": "MAVAS-TFIPGLNPQNPHYIPG-----------------------------------YTGHCPLLRFSVGQTYGQVTGQLLRGPPGLAWPPVHRTLLPPIR-PPRSPEVPRESLP-VRRGQER--LSSSMIPGYTGFVP------RAQFIFAKNCSQVWAEALSDFTHLHEK--------QGSEELPKEAKGRK---DTEKDQVPEPEGQLEEPTLEVVE-----------QASPYSMDDRDPRKFFMSGFTGYVPCARFLFGSSFPVLTNQALQEFGQKHSPG--------SAQ-DPKHLPPLP---RTYPQNLGLLPNYGGYVPGYKFQFGHTFGHLTHDALGLSTFQKQLLA-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2RRW4-1", "uniprot_id": "CMI2B_DANRE", "id": "A2RRW4-1", "name": "Ciliary microtubule inner protein 2B", "aln": "MDLFPPKFSKVLVTPDPQYIPG-----------------------------------YAGYCPQLKYHVGQTYGQLTAKLLTSP-EVSHSQRLVLQTSPLS-STEKETASRSQIWWSRHGASR--NLETMIPGYTGFVP------LRQNYICKTYAETCRDALSEFNQGQAKRL-----HNASADLSFPVINSVPDFRPRRSNSPLIALSKDPAPYKAPDP-------WKPPGSPYFMEDSSPHKYFISGFTGYVPKARFLFGTGYPTITNKALIQFSKEMKAGPASLQKYSLQEEDSSNLPLIP---TIYPSKTGLLPSYTGHIPGYRFQYGHTFGKLTHNALGHTASQKNAGAIRLS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JRP4-1", "uniprot_id": "CMIP2_DROME", "id": "Q7JRP4-1", "name": "CIMIP2 protein CG18335", "aln": "--------MDHAITPEPHLVPG-----------------------------------YTGHCAQNRDRVGRTYGRQTHKLLIDPCIYHAPELIVAPIHAKRGLKDYPTEQELKILRTREGLVDSVYRHPILPGYAGFVPNKVSQIGKRYVAAASAGVARHETLMELYRCENRTLRHRDLLESGNGLFDRKINERLLPQTYYRSPLILVTGVSKGIKDETCPPKTEKLCYSKFTSPHFLEDEDADKFIINGYSGHIPMSVTRFGESNKVLTNRALCSFSDYMYKRKRDTWCCGQDLSRPSITCPPVGHFVVYHEDSGMVPNYAGHVPGETYKFGRTYAKTTYDAKRWLEVHKNLTVLPEVANLDYAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :** *:*:*. : :*:***: * :** .* . . . *.* .::***:**:* : . . . ::: :: : . : . * . . . . **: ::* .. *:::.*::*::* : ** . .:**:** .*.. .. .. *::* * *::** :::* *:.: *::* :*: . ", "identical_positions": 48, "similar_positions": 78, "identity": "13.11%" }, { "cls_id": "homologset.agr.HGNC:34243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEL3-1", "uniprot_id": "D3ZEL3_RAT", "id": "D3ZEL3-1", "name": "", "aln": "MEDVGQNLLDDEDEITEIPTLEAIKQNLKYLNSDLEKDLQRLDEANQTLLRKIQKKEESIQSLERDIALSIGRVPERDDFNEIIVQKETALKDLELEIAKLEKKNKTLSKNVMELQKKISKGTKNAVSDPETLKKKVAELKVKLQKSTESCAQQEKEIAKMESDYQSVFQLCEDQAHYIKKYQEILREMEKEKEVMLLEKEISKAQNDSSQVVKPGSTLVETIQSNMEKNIIKKQKRKFWLRHFRYLFFMIMIVIRLLGYVFFHLQYINPDFLVDTLPMLMSRSSLKWLRDILFPFLTLEVEDVLPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X59-1", "uniprot_id": "TMC5B_MOUSE", "id": "Q80X59-1", "name": "Transmembrane and coiled-coil domain-containing protein 5B", "aln": "MEDAGQNPLDDEAEITEIPTLEAIKQNLKYLNSDLEKDLQRLDEANQILLRKIQKKEESIQSLERDIALSIGRVPERDDFNEILAQKETALKDLELESAKLEKKNKTLSKNVMELQKKISKGLKNIASDPETLKKKVTEFKVKLQKSTESCAQQEKEIAKMESDYQSVFQLCEDQAHYIKKYQEILREMEKEKEVMLLEKEISKAQNDSSQVVKPGSTLVETIQSNMEKNIIKKQKRKFWLRHFRYLFFMVMIVIRLLGYVFFHLQYVNPDFLVDTLPMLMSRSSLKWLRDILFPFLTLEVEDVLPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MYB1-1", "uniprot_id": "TMC5B_HUMAN", "id": "A8MYB1-1", "name": "Transmembrane and coiled-coil domain-containing protein 5B", "aln": "MEDVGQNPLDDVKNIFFASSLEAVKQNLDCLNSDLEKDLQKLDMENQVLLRKIKEKEETISSLERKLALSLEEAKEEEELNYVIDEQEESLRELELETAKLEKSNAILSRNVVEVQKKISGLFTNIGLEEETTKQILEEMKARLQKSTESCAKQEEELAKIESDYQSVSDLCKDQVYYIKKYQEVLRKMKEEKETLLLEKQISKAQDDSSQTVKPGSILADTTQRNMERTTIKKQERRCWYKYFQYLTFMVLVFIRLLAYVIFHLQYINPDLLVDVLPLVLSRGTLESLRKVSHPFLTLAVEEALPH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*** *** :* .:***:****. **********:** ** *****::***:*.****.:***: .. *.:::* :: ::* :*::**** *****.* **:**:*:***** .* : ** *: : *:*.:*********:**:*:**:******* :**:**.:*******:**:*::***.:****:*****:****.***** *.:* * ***:. ****:*: * ::*:** **:::.****.**:*****:***:***.**:::**.:*: **.: .***** **:.***", "identical_positions": 184, "similar_positions": 84, "identity": "59.93%" }, { "cls_id": "homologset.agr.HGNC:34244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQ79-1", "uniprot_id": "T170B_RAT", "id": "Q7TQ79-1", "name": "Transmembrane protein 170B", "aln": "---------------MRAEGADHS---MINLSVQQVLSLWAHG-TVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVLSIIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P86050-1", "uniprot_id": "T170B_MOUSE", "id": "P86050-1", "name": "Transmembrane protein 170B", "aln": "---------------MRAEGADHS---MINLSVQQVLSLWAHG-TVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVISIIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T4T1-1", "uniprot_id": "T170B_HUMAN", "id": "Q5T4T1-1", "name": "Transmembrane protein 170B", "aln": "---------------MKAEGGDHS---MINLSVQQVLSLWAHG-TVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVISVIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPR6-1", "uniprot_id": "A0A8M9PPR6_DANRE", "id": "A0A8M9PPR6-1", "name": "", "aln": "MCPPSSGRFLSRRAALQPPGANMNKDYSINLSVQQVLSLWVQGEATLKHFTEMWYWVFLWCLFSSLFVHSAVGLLMCVTLQRHKRGRLITLVLISVGFLASLGGGVITSAAVAVVYRVAGKDMAPLEALVYGVGQTALTVIISFSRILATL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. *.: . ************.:* :.*:::******:***.********.*.*:** * ****::**::::: :*:*****: *.:******* :******:********:*****.**:***********", "identical_positions": 89, "similar_positions": 35, "identity": "58.94%" }, { "cls_id": "homologset.agr.HGNC:34246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NJL1-1", "uniprot_id": "ZSA5B_HUMAN", "id": "A6NJL1-1", "name": "Zinc finger and SCAN domain-containing protein 5B", "aln": "MAANWTLSWGQGGPCNSPGSDTPRSVASPETQLGNHDRNPETWHMNFRMFSCPEESDPIQALRKLTELCHLWLRPDLHTKEQILDMLVMEQFMISMPQELQVLVKVNGVQSCKDLEDLLRNNRRPKKWSIVNLLGKEYLMLNSDVEMAEAPASVRDDPRDVSSQWASSVNQMHPGTGQARREQQILPRVAALSRRQGEDFLLHKSIDVTGDPNSPRPKQTLEKDLKENREENPGLSSPEPQLPKSPNLVRAKEGKEPQKRASVENVDADTPSACVVEREALTHSGNRGDALNLSSPKRSKPDASSISQEEPQGEATPVGNRESPGQAEINPVHSPGPAGPVSHPDGQEAKALPPFACDVCNKSFKYFSQLSIHRRSHTGDRPFQCDLCRKRFLQPSDLRVHQRVHTGERPYMCDVCQKRFAHESTLQGHKRIHTGERPFKCKYCSKVFSHKGNLNVHQRTHSGEKPYKCPTCQKAFRQLGTFKRHLKTHRETTSQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RB12-1", "uniprot_id": "M0RB12_RAT", "id": "M0RB12-1", "name": "", "aln": "MATNMPSDS-------LVRSGQPLSLISQAKHEERQNYDPDFWHMKFRDFSPSEGSDPIQDLRRMSELCYQWLRPDLNSKEEILDQLVLEKFLISMPLELQALAKENRVRRCKDLEEMMLKARKHQKWSIIYSQGQAYLLRDSSVEEAEASPDEWGDCKDLFQEHQSNESKESLYRGQAIPELQNLSEETEEPSTSQEENILLGLIPGRVQQDYLRPEHSLGNGSVPDWEEA-GASVPVGQDP------HPTQG----PALSLREKGAMQPQEYTVVGAVPSSTHIRERYLALNRDLQSLRSFGGFNLPTSQGVASYTGNAEDRLKTANPETAHPQPVEQVNTLAGQ-----AQFQCPQCKKSFLYKSHFTLHWRSHTGERPFKCNLCNKAFLQPSDLRVHRRVHTGEKPYSCEVCGKEFAHGSTLQGHSRVHTKEKPYVCENCGQCFSHKGNLTVHFRIHCGLRPYICKKCNKAFRQQGTWKRHMKTHWKKRKAPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VDQ5-1", "uniprot_id": "Q9VDQ5_DROME", "id": "Q9VDQ5-1", "name": "", "aln": "MHTNVDSRD------------LKCRICLVQPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLR-----------------------------SLCQQTEKDLKE--------------QKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDS---------------------------------------------------------------------------------------------ELEYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEESVYSLS-------------------------PKPVTFEDEDSGQ----AASFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSHEKSHKRTKEVK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* : : : ::: : * *:. : .:: * **. *: : *:: *. : : : : .: * .. : :*: .: :. .. : . * * * . . . * *. . ** . * * *:: : ::: * : *:..:*.:*::*.* * *..:* * ..***::** *: * ..**. ** *.*:** *:*: *: *.: *.:.. * ** : * * :*: * *:*:* * : * *:* .. . ", "identical_positions": 66, "similar_positions": 93, "identity": "13.28%" }, { "cls_id": "homologset.agr.HGNC:34294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RB12-1", "uniprot_id": "M0RB12_RAT", "id": "M0RB12-1", "name": "", "aln": "MATNMPS-----DSLVRSGQ--PLSLISQAKHEERQNYDPDFWHMKFRDFSPSEGSDPIQDLRRMSELCYQWLRPDLNSKEEILDQLVLEKFLISMPLELQALAKENRVRRCKDLEEMMLKARKHQKWSIIYSQGQAYLLRDSSVEEAEASPDEWGDCKDLFQEHQSNESKESLYRGQAIPELQNLSEETEEPSTSQEENILLGLIPGRVQQDYLRPEHSLGNGSVPDWEEA-GASVPVGQDPHPTQGPALSLREKGAMQPQEYTVVGAVPSSTHIRERYLALNR----DLQSLRSFG-------GFNLPTSQGVASYTGNAEDRLKTANPETAHPQPVEQVNTLAGQ-----AQFQCPQCKKSFLYKSHFTLHWRSHTGERPFKCNLCNKAFLQPSDLRVHRRVHTGEKPYSCEVCGKEFAHGSTLQGHSRVHTKEKPYVCENCGQCFSHKGNLTVHFRIHCGLRPYICKKCNKAFRQQGTWKRHMKTHWKKRKAPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NGD5-1", "uniprot_id": "ZSA5C_HUMAN", "id": "A6NGD5-1", "name": "Zinc finger and SCAN domain-containing protein 5C", "aln": "MAANCTSSWSLGESCNSPGSEPPQSMPSPATQLGNHDSDPETCHVNFRMFSCPKESDPIQALRKLTELCHLWLRPDLHTKEQILDMLVMEQFMISMPQELQVLVMMNGVQSCKDLEDLLRNNRRPKKWSVVSFLGKEYLMQESDVEMAEAPASVRDDPRHVSSQRTSSVNQMCPEEGQASQELQTLPRVPALFRRQEEDFLLPETTVMKGDPKALRPKPTLEKDLEEDREENPGLTSPEPQLPNSPTGVVGAKEGKEPQKRASVENVDADTPSACVVEREASTHSGSRGDALNLRGLKRSKPDATSISQEEPQGEATPVGNRESPGQAEINPVHSPGPAGPVSHPSGQEVKELLPFACEVCGKRFKYRGKLAVHTRSHTGERLFQCNLCGKRFMQRIGLQFHQRTHTGERPYTCDICQKQFTQKSYLKCHKRSHTGEKPFECKDCKKVFTYKANLKEHQRIHSGEKPHKCSKCPRAFGRPATLRRHQKTHREATSQ--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* .* :* .*. * *: * *.: .:: **: *::** ** .: ***** **:::***: ******::**:*** **:*:*:**** ***.*. * *: *****::: : *: :***:: *: **:::*.** ***... .* :.: .:: *. .: . .*** ***.*.. . .:*: :* : : . ***: :* :. * ** * : * * *:.. * . : . * . : . *.* ..*: : ** : : * .**.: .:. .** *: .** *. :: . * *. *. :** * * * * * *:.::::* ******* *:****.* *:* .*:.*:*.****:**:*::* *:*:: * *: *.* ** ***: *::* : *::*.**. * ***.* :*: *.** :** : .* :** *** : . ", "identical_positions": 180, "similar_positions": 146, "identity": "36.14%" }, { "cls_id": "homologset.agr.HGNC:34295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQP5-1", "uniprot_id": "A0A8I6AQP5_RAT", "id": "A0A8I6AQP5-1", "name": "", "aln": "MKGLYQAAGRTLVTLGSLSIFSGSIAFFPVFSCKLWYTGWSVWIACPIWNGALAVTAGSLVLLAHREWTQRHLWEAVFTFVVLSILGCPLHFAVALQSALLGPYCFYSFSGVSGTNYLGYAVAFPFPYTKFPSVCVDPLHYEEYHLTLQALDLGLSLTLFCVSVAVFIKLSARLMQTGHVNTGGPRHAPDVTPRKGCFKAAGTAIRALSWGAGLSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6V3-1", "uniprot_id": "TM212_MOUSE", "id": "Q8C6V3-1", "name": "Transmembrane protein 212", "aln": "MKGLYQAAGRTLVTLGGLSIFSGAIAFFPVFSCKLWYTGWSVWIACPIWNGALAVTAGSLVLLAHREWTQRHLWEAVFTFVILSILGCPLHFTVALQSALLGPYCFYSFSGVAGTNYLGYVVTFPFPYTKFPSVCVDPLHYEEYHLTLQVLDLCLSLILFCVSLAVFIKLSARLMQTGYIN--GPENPQ---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NML5-1", "uniprot_id": "TM212_HUMAN", "id": "A6NML5-1", "name": "Transmembrane protein 212", "aln": "MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGYAVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHINMQLPAGNPNPFSP----------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********** ***** **: ** ******** * *:***** ***********:*:* *:***:******:* **.****:***:******::**:**************::*******.*:**:**:*** .**** **********.*** **: *:*.*::*********:*.*::* * ", "identical_positions": 139, "similar_positions": 30, "identity": "64.35%" }, { "cls_id": "homologset.agr.HGNC:34296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6H694-1", "uniprot_id": "LRC63_MOUSE", "id": "A6H694-1", "name": "Leucine-rich repeat-containing protein 63", "aln": "MKKSIYRSLKTQQHPLLLRRPLPPKLPKVPLLKKKVRIVHTVKAREPKEETYGKFDPDESAFVKMDQN------VSQSQRPTSTQTICLDYDHKALERVVNIFPHQHRVRRFHWKVPKSTAGSMFIPRCLSASSRIFKNTLSQMKKRAKKSSKKEVKEDGYLTKKTFN-TLVLSKEFSKPSPTSYSRFIASKFKPLGTQFHPAPKISGYSQELPLLRDVKRAALSPVPSTSSVIPEPQWSERTHPSAAPSKVV-LNTGSLPPARSLPTPVLPRKPLRQAMIENAAAAAAAAAAAAAATTTTTTTTTTTTTAVTTTAAVSGKTEAHKPPETVQRTTRTIGPDAHVLRGEGFKAVAATRSETVLALTTLAIINCQIYGRNALNLKGFFLANCPDLTPVAFQLVYLNLSFNDLNQFPIEILYLQNLQVLKLRNNPIKEIPSEIHLLTYLRIFSIAFNYITKLPDGLFCLNYLEELDVSYNEIENISNEIQKLRSLEKLIVDGNPITSFPPGILKLNLIKLQIENTFTCSQFWLESSWNDPQQLTQICSLFLVKN---KLLDYIPDAVRKSLKSTSECDWCHGPKFGEGFRIIRSCDIFGVSHVPIMFHVCSSTCYRDIRETSFVLEGFPSRRIALHMDWVKESKVSNVSFYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8G0-1", "uniprot_id": "LRC63_RAT", "id": "Q4V8G0-1", "name": "Leucine-rich repeat-containing protein 63", "aln": "MRKRIYHSFKTQQHPLLLRRPLPPKLPKLPLVKKKVRIVQTGSAREPQEARR-KFDTEESALVKIDQS------VSQPQKPASVQNVCLDYEHDEPERVVNIFPHPHGVRRLHWKVPKSAAGSMFIPRCLSASSRVFRKTLSQIKR-ARKSLKSKQDED--LTKKPFSNTLVISEELSKPLPPSYSRLIASRFKHSGTKFRPAPKISHYIQELPLLKDVKETVLSPISSASSAIPEPEWSERPLPKTTIGKVIQLNTGSLPPAHSLPTPALPRKPPRQIMIEN--------------------------------AVMTRKTETQKPVEITLRPTRRLDPDAHVLRGDGFKAVGATRSETILALTTLAIINCQIYGRNALNFKGFFLAQCPDLTSVAFQLVYLNLSYNDLHQFPGEVLYLQNLQVLKLRNNPIREIPSEIQQLKYLRKFTIAFNFITSLPAGLFCLNYLEELDVSYNEIENIPNEIQKLRSLEKLTVDGTNITAFPPGILKLNLVKLEFENTFTIPPFWLENSCNNPPRLTHICSLFIVKNNLHKILDYDPVVVQKYLISTSDCDWCHGPKFGEGFGIIRSCNIFGLSHVPIKFHVCSLSCYLEIRESSFVLEGFPSRRIALNMDWVKERKVSNVSFYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05C16-1", "uniprot_id": "LRC63_HUMAN", "id": "Q05C16-1", "name": "Leucine-rich repeat-containing protein 63", "aln": "----------MQKPPLLLRRPLPPKFTKLSLHEKKTHTAKTG----KIESLHVAFTEDETTSIKMDRTRFPDVLRNQSLTPINIQNIFLD--HCVQERVTAISSPQKSTKHVREQIPDTATGSIFFPHCNSASTRIFGKQTNKMES----SRKFKTMKD-VYTEKRLENILILSSKFSKPKSTPGS-VIAQKLEKMHPKHQPLPESPGYTYQH-ISRDLSATVPSPPPMTVSMKPEGQWPEHFKSTAT----LTLRVTEFPGFVSLPTPVLPRKPHRQSVIETLVTENG-------------------------NIESVPKQIPPRPPE-GLTKTEKIESEIHVVRGEGFKTVAATRYETITAMTNLAIVNCQVYGRNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKLNLTKIQFENNFTHPCFWRDNYLNNPQQLTQIISLFIVQNKLHKFYDKIPVEVQKLLKCTSRCEWCHGPKFGEGFRVIRSCDIFGASQLPVMFYVCSPSCYRRIKESSFVLDGSPSRRIALDVELSKEL---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ***********:.*:.* :**.: .:* * * :*:: :*:*:. .*. * . *.: ** * ***. * . : .::.: ::*.:::**:*:*:* ***:*:* : .::: * * : :* *:* :. *::*.::*** ... * .**.::: .:.:* *: . * : : :*:. :. ** . : * ** :*.*: ..:: : *.. .:* *****.***** ** :**. * . :* * *. : .: **:**:***:*.*** **: *:*.***:***:*******:****: :*****.:****:*****:***: ** *:* *:***:********:******: * :** *:**** ** ** ***.*.***********: *.************ ***. :: ** ******* *:::**.** . ** :. *:* :**:* ***:*:* *: * * *:* * .** *:*********** :****:*** *::*: *:*** :** *:*:****:* *******.:: ** ", "identical_positions": 278, "similar_positions": 160, "identity": "42.84%" }, { "cls_id": "homologset.agr.HGNC:34297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZC99-1", "uniprot_id": "D3ZC99_RAT", "id": "D3ZC99-1", "name": "", "aln": "-MSAQDLVACLCQEGDKHLALGELPLATAFYLAAFSCHAPSAVRHVRAVLTESPGAPVVATLEAWCRGNSQIPAIHWDGMAVVSLTGTLASAFLGAICPDHPATVLYPLAGLLAQG--RHVEVVQRCNTLLDAH------SQQALELQLMRALAWVLSVDQAREGIAAYLQNFASSADRTVAFIRSHQQPYLPRLLGTLQNYLSG----------------HLKTSASQQEANCRGLLEALDPRGSWMGAMSPEALLHRGRFEDCQAACSRDLQPDST--GSRPQGEHLAALLVTRAAATFFQDGPVGDMLRDLHEAFSESPIGARRQFQALLSSEDRERLQ-AQAKEAADLGFARFLEAVRSRVELRRDADRELLVPVTRALRVLLRVAPARRRPALGTRLAECLLLAGDVAGARAQCERLLRPRRPGERAGNHTGEHAPLLALRGFCALHAGDAQRAREDFQAVVERAAPHAGGCVRALCGRGLLRVLAGSAFLGALDYVTACRLRPEEALLVAKAYVPWNQRGLLLTVLREEGRKMLL-----------RSPSYAVKAAQAQEGDAYGVYQLATLLTEMDAGDETSCLLAVDALYRLGRLEDAHKSLLVALSRRPQAAPVLVRLALLQLRRGFCYDANQLVKKVAQSGDTACLQHTLDIFRREDLQLLQDHCHTRALSILRARPGGSDSEAHTREAIAYLSLAIFTAGSRASESLLVRARCYGLLGQKKTAMFDFNSILREEPGNVKALCGRALVHLALDQLQEAVDDMISALKLDPGTVITEILSLKTEVQLPLTQGLYTRSRALLNQCLDAG-VPLREEDTQGLLATGEALIRINAAQSSWHLLLTDILTGLGKYQEAGTHLQEALHLTPSSEATQARRGLLQLKKGDVSAAARDLRCLAEIDTQDLSFLLRLLESAERQSLMQTAAKEASNLLDLGNPGQALSYCSLAIL-AGGSSPYHLRLRMACLTQLQEYDRALRDLDRVLYQPTEDS--DLPRRTEDLCTRGRLLLSLGDKDGAAGAFTQALALAPAQAQSSLLEQPGRATTASVFLIHGQRCLEKQHFEEAWTAVRNGLLVDPSHSGLKKLKLRTRKEAASGCRLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0Q3-1", "uniprot_id": "TTC34_MOUSE", "id": "Q8C0Q3-1", "name": "Tetratricopeptide repeat protein 34", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLL-----------RSPSYAGKAAQAQEGDAYGVYQLATLLIGMDAEDETSCLLAADALYRLGRLDDAHKSLLVALSQRPQAAPVLVRLALLQLRRGFCYDANQLVKKVAQSGDTACLQHMLDIFHHEDLQLLQDHCHTRALSILRARPGGSDSEAHTREAIAYLSLAIFAAGSGGSESLLVRARCYGLLGQKKTAMFDFNAILREEPGNVKALCGRALVHLALDQLQEAVDDMVSALKLDPGTVIPEILSLKTEVQLPLTQGLYTRCRVLLNQCLHTG-VPLREEDTQGLLAMGKALIRINATQPSWRLLLTDILTGLGKYQEAGTHLQEALHLTPSSEAAQARQGLLQLKKGDVSAAVHGLQCLAERDTQDLGFLLCLLDSPERQSLVQTAAKEASNILDLGNPGQALSYCSLAIL-AGGNNPYHLRLRVACLTQLQEYDRALRDLDRVLQHPAEDS--DLPRQSEDFCTRGRLLLSLGDKDGAAGAFTQALALAPAQAQNSLLEQPGQAMTASVFLIHGQRCLEEEHFEEAWTAVQNGLLVDPSHSGLKKLKLRTRKVATSGCRLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MYJ7-1", "uniprot_id": "TTC34_HUMAN", "id": "A8MYJ7-1", "name": "Tetratricopeptide repeat protein 34", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQRSPRAGPSRAQG-----------RREAAETGGPTTQEGVACGVHQLATLLMELDSEDEASRLLAADALYRLGRLEETHKALLVALSRRPQAAPVLARLALLQLRRGFFYDANQLVKKLVQSGDTACLQPTLDVFCHEDRQLLQGHCHARALAILRARPGGADGRVHTKEAIAYLSLAIFAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTVVPELRSLKPEAQALITQGLYSHCRALLSQLPDTG-APLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQEAGTLLDAGQPRQALGYCSLSVL-ASGSSACHLRLRATCLAELQEFGRALRDLDHVLQEALGDG--DLPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPSLAQNSLCRQPGRAPTARMFLLRGQCCLEEQRHAEAWTAVESGLLVDPDHRGLKRLKARIRREASSGCWLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TAJ5-1", "uniprot_id": "A0A8N7TAJ5_DANRE", "id": "A0A8N7TAJ5-1", "name": "", "aln": "MNGKHKGAADLCREGDKILFSGDPGRAAALYTQAFGNHAGSTVRHVRG-LDTGHLEEVIATLEAWLDGSSHN--------SIEGPSKGLVAVFLSTLCPNNVSASLYKMESVMQGTGQASDEIFARCSALLKGKQTPQPVGRTRLVLELTRALACLLSDPQNPKGPQLYLQAFNGNISETVRLVKERQTQHVELIIKAFYQQLSPRYPILQGKVQVEKKSYSTQASEYIDSSKAIEFLLAISPEDIRIRELQAAELFSSGKFTESAEALSLTLELGESQAEYAMTAEKRVCLLVSRAAAHFAAGGRAKEVCKDLGDGFALHPATARQQFQSLFSDSGIGTAARIQLRQQAEKGVSEFREAVLMRPDLRSSKGVELLDPVISQLRALCHLEPDGGGRELRVRLADCLLLRGEHREALSISSQLAAPAQQSYQN--------TVQVLRGYSRLFIEDHKGALEDFQAVIEHNTPHPPSCVRALCGRGILRMMAGSHYLTALDYATASRLQLQDAAVTVRCLVPWNCRGLLCTVLLEQGRVMLEGVEEEKAESNPTAQELEEGHINNKQRSPIGVHALALLLMELQPGTDGPQILTADALYQLGRVEEAYR-LLLNIEHTAPRPPILARLAILQLHRGFLYDAYQLLKKLINSGDTTCLRPLLSVTSLQDRALLEKHCHTASKRILCG----QQAESAIREAVAYLSIAIMASGGGAIDSLLERARCYALLGQWKTAIFDFTAILKKQPDNVQSLCGRAFTYLMLNQQKECTLDILAALQCGAKEATQSMLSLKDKARRLISEWLGQHCRKSLADILLSNPVPCREEHLREAFLISGALMNTDCREPRWHLLYIDTLLAKGDVNAAGAHLKQVFGQEPRDAAAKARWGIVKAWQQNYKVSASYLSVVAEKEPATLDFLISLLQSAQRKRLAQAASQQASCVSESGQWEQALALLTLAVRGVSEIKLQYLRQRAACLAQLGLHDRAVSDLSKVIQGHTADGREEQRVWAEDLCRRGRCLLLCSHEESGLQDFSQALDLHEEQALLCVEASLGRQRLAEMYLRFALQNYGEQKLEKAWFLTETGLKVDSGHVELRRLRARIKREVSGPCTVN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . **: ** ** ::. : . :*:.****:***:::::: **: :.: . .*:*.***:***:*** *** **:**: :****:**: *.: :* **: ***: : ** . :.. :**:****:**:::*. . :*** *****.:*** ***:***.::*: :*.**::*****:.:* *:* :*.. *:::**: .. . .: *** :.: ::: * :.* * : :. .* .::. : : . **:. :. :. *:** * * . *. : **:**::.: * . *::** *::: : : :. * :** :. *. *: **::.:*: * *:*:::*. : : *: ***. :*:: .. . :** * :**::* ..**: **.:*: *. : :**:* :** ** ..: .. *:*** * * .: . *: * ::* . ::: :** ...** **..* *::*: * :: .:. * ::", "identical_positions": 171, "similar_positions": 196, "identity": "15.45%" }, { "cls_id": "homologset.agr.HGNC:34298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LW19-1", "uniprot_id": "A0ABK0LW19_RAT", "id": "A0ABK0LW19-1", "name": "", "aln": "MKGLKETVGGLEVGTQKCLRSLLLIWGVFLRLPQIQGRRRGPSRPQSKATLLTKTGDQWWSRATPYLRLLRFEIIDTFKSLTKELLRQEHLTQAPQRNDPHRVTDRTFFIDGSNQNLKTIPPEILALKELEEVHLENNQISEIPQGIQHLEKIKVLYLHNNSLQNLCQELGSLSNLESLDLSGNLLVLSSLQVICRLRTLRELRLYNTGLTEVPSGICKSLHHLELLGLSENYLESLPKEIVNQTKLREIYLKQNHFENFPCDLCVLCNLEVIDLDDNKLKTIPEDIGHLVRLQKFYVASNHLMGLPESLSHCRKLSVLDLTHNSIHSLPYSLEQLTELTEVGLSGNRLEKVPRLLCNWVSLHLLYLRNTSLHGLRRSFKHLVNLRFLDLSQNHIDHFPVQICTLKDLEILALDDNKVKQLPPAISSLSKLKILGLTGNDFVSFPEEIFSLVSLEKLYIGQDQGSKLSSLPENIKKLTNLKELYIENNQLEQLPASLGLMPNLEVLDCRHNLLRQLPDAICQTRDLRELLLEDNLLSRLPENLDHLVNLKVLTLTDNLMEDPPMEVCEQGNEAIWRHLKENRIRKVMATKIQAWWRGIMVRKGYGSYEELLKARKKGKSPPKDKKGKAAPKGKPAKGNKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H6A4-1", "uniprot_id": "LRIQ4_MOUSE", "id": "A6H6A4-1", "name": "Leucine-rich repeat and IQ domain-containing protein 4", "aln": "---MHHSSSGSRCVLQNGLELTVILP-----------------------------------------RLHRFDIIDTFKTLTKELLRQEHLPKVLQKKEPHQLTDRTFFIDGSNQGLKTIPSEILALKELEEVHLENNQIAEIPQGIQQLQNTKVLYLHNNSLQDLCPELGALSSLESLDLSGNPLVISSLHVVSRLRTLRELRLYRTGLTEIPTGICKSLHHLELFGLSENFLESLPEEIVNQTKLREIYLKQNHFEVFPCDLCVLYNLEVIDLDENKLKSIPGDIGHLVRLQKFYVASNHLMSLPESLSQCSKLSVLDLTHNSIHSLPSSLELLTELTEVGLSGNRLEKVPRLLCSWVSLHLLYLRNTSLHGLRDSFKRLINLRFLDLSQNHIEHFPVQICALKNLEILALDDNKVRQLPPSISLLSNLKILGLTGNDLLSFPEEIFSLISLEKLYIGQDQGSKLSSLPENIKRLMNLKELYIENNRLEQLPASLGLMPNLEVLDCRHNLLKQLPDAICRTRNLRELLLEDNLLCCLPENLDHLVNLKVLTLMNNPMVDPPIYVCNQGNEAIWKHLKENRIRKMMATTIQAWWRGIMVRKGYGSYEELLKARKKGKSPPKDKKGKKAAKGKPEKGNKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NIV6-1", "uniprot_id": "LRIQ4_HUMAN", "id": "A6NIV6-1", "name": "Leucine-rich repeat and IQ domain-containing protein 4", "aln": "--------------------------------------------------------------------------------MSKDIKSVEHSPKIHQRNDPQHVNDRTFFIDASNQSLTAIPLEIFTFTELEEVHLENNQIEEIPQEIQRLKNIRVLYLDKNNLRSLCPALGLLSSLESLDLSYNPIFSSSLVVVSFLHALRELRLYQTDLKEIPVVIFKNLHHLELLGLTGNHLKCLPKEIVNQTKLREIYLKRNQFEVFPQELCVLYTLEIIDLDENKIGAIPEEIGHLTGLQKFYMASNNLPVLPASLCQCSQLSVLDLSHNLLHSIPKSFAELRKMTEIGLSGNRLEKVPRLICRWTSLHLLYLGNTGLHRLRGSFRCLVNLRFLDLSQNHLHHCPLQICALKNLEVLGLDDNKIGQLPSELGSLSKLKILGLTGNEFLSFPEEVLSLASLEKLYIGQDQGFKLTYVPEHIRKLQSLKELYIENNHLEYLPVSLGSMPNLEVLDCRHNLLKQLPDAICQAQALKELRLEDNLLTHLPENLDSLVNLKVLTLMDNPMEEPPKEVCAEGNEAIWKYLKENRNRNIMATKIQAWWRGTMVQRGFGKFGELLKPQKKGKTSPKDKKGKKDVKGKPGKGKKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 367, "similar_positions": 123, "identity": "57.34%" }, { "cls_id": "homologset.agr.HGNC:34299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TXF5-1", "uniprot_id": "LRC66_RAT", "id": "Q6TXF5-1", "name": "Leucine-rich repeat-containing protein 66", "aln": "MKDFYARVTVMVTGLCFVGTVTNPSRKSSLSLH---QQDGDLLANWSSTR------HTSQKTDTVDRNSYFFRVLFQPHT--KERHTNHLDRTNHRLSKVTLSCLAHLRALEMLNLGDDVIHSLCLDLSLPSSSRQKRHRSRFRGRHPRLKVLLLQRNQLGPTPKGLWKLKPLCSLDLSFNRRVGIGLSGFHGCLQLKSIYLKNNKILTIHPEAFKGLKKLQVVDLRSSALTMLVPIVTIALEWPNLELGLADNQWQCNESDANFQNIASVSWGEIWKAVCNTPVENEKPYVEASQIRISRDIHLPRSPSSDLQSLIQSKAEKPRAGMDVHLSALEKKAQVGYGDLKGIWLQSPMELRDSQGGPVTDRKDDKPPDLALAVCLSVFITFVVAFCLGAFARPYIDRLRQQRCLNKRPGSENAYSNEGFHDDVEAAQHVQHQGTDLCQTTHHLNLFENQDPSWGTEAIPHGAVLSERMLGSNGMDPSSQQSPGQFEDSGEARSGDGNMFPNGRVVHPAVHGLPSADAQKPISPGQ---HHYDVPEESLYDTVAQEYSLLDNAMDRSSVAGCLGTFPNSINSGRDELCPSQPRDVVASFSKTLAHMSTREAEESVERGFPEPLGAMGSQIESSEERQVSNSIRELATQQASFQEVDVEERLAHVYSEALYNDT----PSHMP-RHSSGHDVASATEEAVQRDASFDPHDDLVTNYESDSDEGSLFTLSSEGSQDTRSLTEEQAFVESGGDSQPLPSRNLGEYKDSVTSAESVED-ITSQQTLEKREAQEAHLGNTLISGPDSCVHETHLENDSSPLDPENVPTWTQPPDHKLAHHETLGTFVYG-DIGPQSEAVDWLYSLRDLEFPNIDS-SPSPPCSDQDPSDPEEHDTK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0B3-1", "uniprot_id": "LRC66_MOUSE", "id": "Q8K0B3-1", "name": "Leucine-rich repeat-containing protein 66", "aln": "MRDFYVRVTILVTGLCFVETVTTPSRKSSVSFNPEYQRNGDLLVNWSSIR------HVSQNTDAMDRSFYFFRVLFQPHTQ-KERHIKPPDRTHHRISKVTLDPLAHLHALEILNLSNKAIHYFSLDQPLPPSSHQKRHGGHSHSRLPRLQVLILQRNQLSGTPKGLWKLKSLRSLDLSFNRIVHIGLSDFHGCLQLESIYLKSNKICTIHPKAFKGLKKLQVVDLRSNALTTLVPIVTIALELPHLELGLADNQWQCSESNVNFQNITSSSWREIWKAICNMSVENKRPNAETHQIRKSRDTHLLLSPPSDLKSLIQSKAERPQAGMDMHLSALGKEAKDGYGDLRGMWPQSPVELRDSQDEQVTDRKDDKPPALELAICLSVFITFVVAFCLGAFARPYIDRLRQQRCSNKRPGSDNAYSNKGFHGDIEGAQHMEYQGTDLHQTTHHLHLSENQNPSWVAEPIPHSAVQSEQMLGSNGTDPGHQQSPEQLKDSNESRSGDSIVLPSGPVAHLALHGLPNADAHKAISPVQ---HHHDFLEEAHYDTVAQEYSLIDDVMDRSSITGPLGTFPSSVESRRDDLHPSQPRDVVASFSKTLAHANTREAEGSMETGCPEPLGAMDSQMGSSEERQVSNSIRELATQQPSFQGVDAEERLSHVYSEVLHNDP----PSLRP-RWGSGHYVIPATGEPVERDAPFDPHYDLVTNYESDSDEGSLFTLSSEGSEDTRSLAEEQASVENDGTSQPLPSRNLGEYKDSVTSAESVED-LTSQRIPEKCEAQEAHLRNTLISGPDSCVCETNQENDSSSLDPENRSTWPQLPGHKLSHHETLG--TYG-DIEPQSEAVDWHYSLRDLESPNVDS-SPSPPYSDEDLSGPEDRARKRSKHW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CR7-1", "uniprot_id": "LRC66_HUMAN", "id": "Q68CR7-1", "name": "Leucine-rich repeat-containing protein 66", "aln": "MKNLYFRVITIVIGLYFTGIMTNASRKSNILFNSECQWNEYILTNCSFTGKCDIPVDISQTAATVDVSFNFFRVLLQSHTKKEEWKIKHLDLSNNLISKITLSPFAYLHALEVLNLSNNAIHSLSLDLLSPKSSWVKRHRSSFRNRFPLLKVLILQRNKLSDTPKGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSG-LRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSG------NDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQS-LWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELES--DCDSDEGSLFTLSSISSESARSKTEEAVPDE-----ESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDSDILK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::* ** :* ** *. :*..****.: :: * : :*.* * . **.: ::* . *****:*.** :* : : * ::: :**:**. :*:*:***:***.:..** :.** * ** *** . :.* * *:**:****:*. *********.* ******* : ** *.**.****:.: **.*** .* *:***.******:** ..** ::*:: **** *:* :.****:***.:* . ***: * ** : *:.:** .: .:.. : * * **: :* ::***:****:*:.* . :*:* *:*: * * *: : * .:*.::. .:.:*:* * * **:********:***.****:***:*** *::* .* ** :*****:**:.*:*.* * : *.* *. ** * *** * * ::. **.:* .:: ** . **. .*** * *. : ** .. ..: :: * *. :: :*. * *: *. * *:***** .* . :. **::* :...* . ::* ** . ::.**:.* *:* .::.: * * * .* .**: *:*****.** *: **. :. . .** *: ***. :.*. ** * * .** * .*. *.*::.:. *. :* : :.************ .*:.:** :** . * :.* ... * **.**:.:*:*: :* * * : ** : :.***.*** : :*: ** *.. .*. ..*.: *.:. .* * .*. * **:*.:* ****** .*:* . :** * : *.*:. : ", "identical_positions": 350, "similar_positions": 264, "identity": "39.11%" }, { "cls_id": "homologset.agr.HGNC:343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10760-1", "uniprot_id": "SAHH_RAT", "id": "P10760-1", "name": "Adenosylhomocysteinase", "aln": "-MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLH-FKDG-PLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDK--------------YPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50247-1", "uniprot_id": "SAHH_MOUSE", "id": "P50247-1", "name": "Adenosylhomocysteinase", "aln": "-MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLH-FKDG-PLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDK--------------YPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23526-1", "uniprot_id": "SAHH_HUMAN", "id": "P23526-1", "name": "Adenosylhomocysteinase", "aln": "-MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLY-FKDG-PLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDK--------------YPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27580-1", "uniprot_id": "SAHH_DROME", "id": "Q27580-1", "name": "Adenosylhomocysteinase", "aln": "-MS-KPSYKVADISLAEWGRKAIIIAENEMPGLMACRKKYGPSKPLKGARITGCLHMTVQTAVLIETLVELGAQVQWSSCNIFSTQDNAAAAIAATGVPVYAWKGETDEEYMWCIEQTLV-FPDGQPLNMILDDGGDLTNLVHEKFPQYLKNIKGLSEETTTGVHNLYKMFKEGRLGVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVCCVAGYGDVGKGCAQALKGFGGRVIVTEVDPINALQAAMEGYEVTTMEEASKEASIFVTTTGCRDIITSVHLQQMPDDAIVCNIGHFDIEIDVDWLNANAKEKVNVKPQVDRYTMQSGKHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKSDK--------------YAVGVHVLPKILDEEVASLHLEKLGVKLTKLTEKQATYLGVSQTGPFKPDHYRY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39954-1", "uniprot_id": "SAHH_YEAST", "id": "P39954-1", "name": "Adenosylhomocysteinase", "aln": "MSAPAQNYKIADISLAAFGRKEIELAEHEMPGLMAIRKAYGDVQPLKGARIAGCLHMTIQTAVLIETLVALGAEVTWSSCNIYSTQDHAAAAIAASGVPVFAWKGETEEEYLWCIEQQLFAFKDNKKLNLILDDGGDLTTLVHEKHPEMLEDCFGLSEETTTGVHHLYRMVKEGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDVGKGCAAALRGMGARVLVTEIDPINALQAAMEGYQVVTMEDASHIGQVFVTTTGCRDIINGEHFINMPEDAIVCNIGHFDIEIDVAWLKANAKECINIKPQVDRYLLSSGRHVILLANGRLVNLGCATGHSSFVMSCSFSNQVLAQIALFKSNDKSFREKHIEFQKTGPFEVGVHVLPKILDEAVAKFHLGNLGVRLTKLSKVQSEYLGIPEEGPFKADHYRY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **:***.** :*** : :**:****** *: *. :*******:******::********* ***:* ******:****:****** :*:**:******:***:***** * * *. **:*********.*:* *.*: * . *:*********:**:*. :* * *************************:**********:****. ************ **:*:*.**::**:*************:*.**::*.: ..:******* *** . *: :* :***********:**** **: ** * :*:******* :..*:::****:********* **.***** **:***:*** *:. ** : ****.*** *** **. ** :*.*:****:: *: ***:. ****.*****", "identical_positions": 294, "similar_positions": 83, "identity": "65.48%" }, { "cls_id": "homologset.agr.HGNC:3430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06494-1", "uniprot_id": "ERBB2_RAT", "id": "P06494-1", "name": "Receptor tyrosine-protein kinase erbB-2", "aln": "---MELAAWCRWGFLLALLP------PGIAG-------------------------------------------------------------------TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYVP-ANASLSFLQDIQEVQGYMLIAHNQVKRVPLQRLRIVRGTQLFEDKYALAVLDNRDPQDNVAASTPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVFRKNNQLAPVDIDTNRSRACPPCAPACKDNHCWGESPEDCQILTGTICTSGCA--RCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMHNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLRGARAITSDNVQEFDGCKKIFGSLAFLPESFDGDPSSGIAPLRPEQLQVFETLEEITGYLYISAWPDSLRDLSVFQNLRIIRGRILHDGAYS-LTLQGLGIHSLGLRSLRELGSGLALIHRNAHLCFVHTVPWDQLFRNPHQALLHSGNRPEEDLCVSSGLVCNSLCAHGHCWGPGPTQCVNCSHFLRGQECVEECRVWKGLPREYVSDKRCLPCHPECQPQNSS-----------------------------------------------------------------------------------------------------------------ETCFGSEADQCAACAHYKDSSSCVARCPSGVKPDLSYMPIWKYPDEEGICQP----------------------------------CPINCTHSCVDLDERG--CPAEQRASP---------VTFIIATVVGVLLFLILVVVVGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFSPDPTPGTGSTAHRRHRSSSTRSGGGELTLGLEPSEEGPPRSPLAPSEGAGSDVFDGDLAMGVTKGLQSLSPHDLSPLQRYSEDPTLPLPPETDGYVAPLACSPQPEYVNQSEVQPQPPLTPEGPLP---PVRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLVPREGTASPPHPSPAFSPAFDNLYYWDQNSSEQGPPPSNFEGTPTAENPEYLGLDVPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70424-1", "uniprot_id": "ERBB2_MOUSE", "id": "P70424-1", "name": "Receptor tyrosine-protein kinase erbB-2", "aln": "---MELAAWCRWGFLLALLS------PGAAG-------------------------------------------------------------------TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLP-ANASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRGTQLFEDKYALAVLDNRDPLDNVTTAAPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVLRKNNQLAPVDMDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICTSGCA--RCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFESMLNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAGVCYGLGMEHLRGARAITSDNIQEFAGCKKIFGSLAFLPESFDGNPSSGVAPLKPEHLQVFETLEEITGYLYISAWPESFQDLSVFQNLRVIRGRILHDGAYS-LTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVNTVPWDQLFRNPHQALLHSGNRPEE-ACGLEGLVCNSLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVWKGLPREYVRGKHCLPCHPECQPQNSS-----------------------------------------------------------------------------------------------------------------ETCYGSEADQCEACAHYKDSSSCVARCPSGVKPDLSYMPIWKYPDEEGICQP----------------------------------CPINCTHSCVDLDERG--CPAEQRASP---------VTFIIATVVGVLLFLIIVVVIGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAVPNQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLEDDDMGELVDAEEYLVPQQGFFSPDPALGTGSTAHRRHRSSSARSGGGELTLGLEPSEEEPPRSPLAPSEGAGSDVFDGDLAVGVTKGLQSLSPHDLSPLQRYSEDPTLPLPPETDGYVAPLACSPQPEYVNQPEVRPQSPLTPEGPPP---PIRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPRAGTASQPHPSPAFSPAFDNLYYWDQNSSEQGPPPSTFEGTPTAENPEYLGLDVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04626-1", "uniprot_id": "ERBB2_HUMAN", "id": "P04626-1", "name": "Receptor tyrosine-protein kinase erbB-2", "aln": "---MELAALCRWGLLLALLP------PGAAS-------------------------------------------------------------------TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLP-TNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVT-GASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCA--RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYS-LTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPED-ECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGS-----------------------------------------------------------------------------------------------------------------VTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQP----------------------------------CPINCTHSCVDLDDKG--CPAEQRASP---------LTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLP---AARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04412-1", "uniprot_id": "EGFR_DROME", "id": "P04412-1", "name": "Epidermal growth factor receptor", "aln": "MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFS----LSVEEEK--------YALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCTHG-CWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPG-HLLRDNGACVRSCPQDKMDKGGE-----CVPCNGPCPKTCPGVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRAD-LCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYIS--NAYKFDNRTCKICHPECRTCNGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIR--KLAPTTDGSEAIAKPDDYLQPKAAPGP------SHRTDCTDEMPKLNRYCKDPSNKN------SSTGDDERDSSAREVGVGNLR---------------------LDLPVDEDDYLMP-TCQPGPNNNNNMNNPNQNNMAAVGVAAGYMDLIGVPVSVDNPEYLLNAQTLGVGESPIPTQTIGIPVMGGP--GTMEVKVPMPGSEPTSSDHEYYNDTQRELQPLHRNRNTETRV------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : :** **. *. *. ::* **. :* :*:. * * **. * .* *:***:**::* * .****::*:** **:**:* *::* : :*:*:** **. *:* :: : : : *:: .* ::*:* * :: * :**: : *.::. :..: * .* * * *. . ****..::** :: *: ** ** * * :*** **.*****.:.**:** :* ...:.: .**.: .**. *: ****:*::**:**. ** :* : *:*. ** .: : .* * *. **. .* *: : * :. . .: : .* : .. ** **: :**.*::****** *.. .: :** *:**. *:** * :. :: *:: .: * :*.*:::.** .:*::* .**:* .: * : ::*.* : . * : * .* * . * .. ***.*. **:.*.:* . *: :* . . : * *****:. *.: * :* . : * *:*** * :.**:. .* . :: * . * **:: * : * *.*. *. : **: .* : . :: ** * :::: * .. .* *. * *** **. .* .::**:*::**** *** **** ****:*:*:*********** * :.*..::.:*:* ***:**. : :**.:*::* : *:***** *****:**::*.::**: ****. **********: **************::*. *********:**. *..**:* ***:****:***.* .* ** :****::***:***:*** :*::.***::****:* * :* ** **::*:* ::.** :*: ** *::*.: *:.:**** *::.* .:.: .. * :.*:. .:. .*..* :. :.:: *..: *. **:..: . :**:: :.: . * ::.:* : : ** : *.*: * :*.* *: *: : * . * . . .:::.*: * .:. * : :: * * *: * *. .*: .: *::: * . . : . . ", "identical_positions": 411, "similar_positions": 374, "identity": "27.44%" }, { "cls_id": "homologset.agr.HGNC:34300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD14-1", "uniprot_id": "D4AD14_RAT", "id": "D4AD14-1", "name": "Leucine-rich repeat and death domain-containing protein 1", "aln": "MSE--------DGSNVEPEGLTRSESLEEPEFIDEISDPSNETSPHSGNTDFNQIYESNSSENTEQPSASSTSQLNGNEETNIEIPFSDTNIEEVIPLSNSESPQSSESSETNEAEEYHPVKFPIGRKFRGRTFNGHHKGFDMESDTFTVHLDAKGLQEFPVDIVKVKYVKYLYLDKNQIKTFQGADPGDLLGLETLSLQENGLSSIPQEIQLFHNLKVLNASYNEISHIPKELLQLGNMRQLFLNSNHIESLPSGLENLRYLETLSLGKNRLTHIPDSLCGLKNLKTLNLEYNQLTIFSKSLCFLPKLVSLNLTGNMIGSLPKEVRELKNLENLLMNHNKLTFLAVEIFQLLKIKELHLADNKLEAISPKIENFKELRLLNLDNNLLQSLPKKISHCVNLESLTLSDNNLEELPKKIRKLKNLRQLHANRNKMIKMAEEISHLSKIHSLEFSGNQITHVPIEIKNCKEITRVELNYNNIMYFPVGLCALQSLDYLSFNGNYISEIPVDLSFSKQLLHLELNKNKITIFSEHLCSLTNLEYLDLAKNQIRKIPHCISAMLSLHVLILSDNKFEIFPKELCSLKNLQLLDISENQLHKIPSEISKLKKIQKLNLSNNNFTHFPAELCQLQTLEDLNISQISGKKLTRLPEEVSRMTQLKALNISNNAIKEIPRNIGELRNLITFHASNNQINSLPSSFLSLNVLQSLDLGGNNLTDLPSAIYKLSSLKEINFDDNPLLRPPMEICKGKQMHTITCYLQRADDRDEKILEKIFHIVANNITETKFEFLQQKLHMARSENSVPVKTTTPLNEGIYQALLKWKTEKR-VSFTAIALKDQLFRALNMIGAYDIMDKITALNLYTSAIKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0R9-1", "uniprot_id": "LRRD1_MOUSE", "id": "Q8C0R9-1", "name": "Leucine-rich repeat and death domain-containing protein 1", "aln": "MSE--------DGSNVEPGGFPRFESLEEP--GSEISDLLDEASPYSKSKDSNQIYEANPSKDTEQSAASFTSQLDRNEEKNTGIPFSETNIADIIPLSIEESLQSSGSSETKMAEDYYPVKFPTGRKFRGRIFNGNQKGLDMKSDNFTVNLDAKGLQEFPVDIVKVKYVKYLYLDKNQIKNFQGIDPGDLLGLEILSLQENGLSSIPLEIQLFHNLKILNASYNEISQIPKELLQLENMRQLLLNSNHIDTLPSGLEHLRYLETLSLGKNMLTYIPDSLSSLKNLRILNLEYNQLTIFSKSLCFLPKLNSLNLTGNMIGSLPKEVRELKNLESLLMDHNKLTFLAVEIFQLPKIKELHLADNKLEAISPKIENFKELRLLNLDKNLLQSIPKKISHCVNLESLSLSDNNIEELPKKIRKLKNLRQLHVNRNKMITMTEEISHLSNIHILEFSGNQITHVPIEIKNCRKITRVELNYNNIMYFPVGLCALQSLDYLSFNGNYISEIPVDMSFSKQLLHLELNRNKLTVFSKHLCSLTNLEYLDLAKNQIMTIPSCISAMVSLHVLILSDNKFESFPKELCSLKNLRVLDISENKLQKIPLEISKLKRIQKLNLSNNIFTNFPVELCQLQTLEELNISQTSGKKLTRLPEEVSHMTQLKILNISNNAIKDIPKNIGELRSLVSFYASNNQISSLPSSFLSLEVLQSLDLRGNNMTALPSGIYKLSSLKEINFDDNPLMRPPMEICKGKEMHMITCYLQRADERDEKILEKIFNIVANSITETNFEFLQQKLNMASSANNMPVRPTTPLNERIYQALIKWKAEKD-VQFTATALRDKLFRALNMIGAYDIMDKITALNLYTSAIKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4D1F6-1", "uniprot_id": "LRRD1_HUMAN", "id": "A4D1F6-1", "name": "Leucine-rich repeat and death domain-containing protein 1", "aln": "MSEKEGMSEVLEDTISQFRKESRSQSMKEPGFIKETSNLINEASDYLEGKSSNQIYETHPRQNTLESTSSSGRKSKRNEEQKKNLQFSETSTRTGTSQSLS---SLTGRTAEYQALVNFLSHETVG-EVSPQVSEENQKQLGLGADNFTVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQGADSGDLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKIKELQLADNKLEVISHKIENFRELRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKITDCISHLNNICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYNIFSLKEINFDDNPLLRPPVEICKGKQLYTIARYLQRADERDEKILEKIFKIVANNITETNFEFLCQKLNLANSETDMPTKSTVSLSERAHQALVIWKTQSNKLSLTAAALRDQLIRALTMIGAYEIMDKITALNLFTRAIKF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :.: : .* :*::** .* *: :*:* : ... *****::. ::* :.::* : . *** : : **:*. . * . . : : * . : . * :. : : ::* :.: :*.***:*:******** **:*:**************.*** *.******* **********:* ****:***::**.*:*.**:****: ** *:***:: .*:*:.:**.** * ** ****** * :***:* .**.*: ********* *.*:******* **:****:*.*****:*******.***:************** *****:*******.** *****:***:* **:***:.:*:*** *. **.*:****:: **** *:**:***:**.***:*:.::: ****.:* ****** **.********::* ::**.**:*****:*****:** ***.***********:***********..**: :**:*:*** **:****.**** .** .** *:*******. **** **:***:*:**::**:***:*:**. :*.:** *****:*.* * :** ******:**:***** .*:****** *:*.***** *:******::**:******.*::::* ****. **.*:***: **.*:* ***:* ***.**:: ************:***:******::: *: ******:**********:****.****:**** ***::* * ..:*.:.*..*.* :***: **::. :.:** **:*:*:***.*****:**********:* ***:", "identical_positions": 521, "similar_positions": 212, "identity": "60.3%" }, { "cls_id": "homologset.agr.HGNC:34301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L3X2-1", "uniprot_id": "A0ABK0L3X2_RAT", "id": "A0ABK0L3X2-1", "name": "", "aln": "MAAVSVVVSPGKEHAKVVVHLQTRPGFPDDRRVG---GGTVTGPRDHLLSVDQIRLVKEARGPPTSLGRVPGSELCALVCVPDWVVRVNMKGPCKEVQKNEDQ-EGEAAATGPQAETLEAKKSWTANSHSALETEGTHGLG---ERVMADLYLESCRANSVVPVSRLLRQGSASELNLQHRGLGPQGIRALASTLTSNLYIKRLDLRDNELGGAGAEALADVLRKNSVISDVDLSENQIGAAGLQAICTALTLNPTVQKMQLQGNRLEEKAAQHLAALLLRHTGLKSLDLSYNQLNDLAGETLGPAVAENTGLTELNLSWNHLRGLGAIAFARGLEANIFLKVLDISHNGFGDSGACAVGEALRVNNVLEELNMRNNRISTSGALKLGLGLQVNQTLRVLIISKNPICSDGCVGLLKSVRSNKSSGLELLDVSGIQVSRECDELASSMSEAFPGLCIKHCTSRRKDWPQATIPAVICTKWL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14BP6-1", "uniprot_id": "LR74B_MOUSE", "id": "Q14BP6-1", "name": "Leucine-rich repeat-containing protein 74B", "aln": "-----------------------------------------------------------------------------------------MKGPC-EVQKNEDQ-EGEAAATGPQAETLEAERSWTADSHSALEAEGTHGLG---ERVMATLYLKSCRANSVVPVSCLLRQEGASELNLRHRGLGPQGVRALASVLTSNPYIKRLDLRDNGLCGAGAEALADVLRKNSIISDVDLSENQIGAAGLQAICTALALNPTVEKMQLQGNRLEEQAAQHLAALLLHHRGLKSLDLSYNQLNDLAGEILGPAVAENTGLTELNLSWNHLRGLGATAFARGLEANIFLKVLDISHNGFGDSGASAIGDALRVNNVLEELNMRNNRISVSGALKLGLGLQVNQTLRILIISKNPIRSDGCVGLLKSVRNNKSSALELLDVSDIQVSRECEDLASSMSEILPGLCIKRYTSRRKDWPQASTPSQPASAPSDSGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZQY2-1", "uniprot_id": "LR74B_HUMAN", "id": "Q6ZQY2-1", "name": "Leucine-rich repeat-containing protein 74B", "aln": "-----------------------------------------------------------------------------------------MRGSCERSGEDEEQKEEAMVACGRLSGVPEAEQGPEANWDSDLETEGTDGLG---ELVRDTLYLRSCRAHSVVPISCFLRQGSAQELNLRHRGLGPQGARALASSLSSNPYVKRLDLRDNGLCGAGAEALAGALSKSSSIHDVDLSENQLGVAGAQALCAALTVNQAMRKMQLSGNGLEEQAAQHLAELLLAHTDLKSLDLSYNQLNDQAGETLGPALAENTGLTELNVSWNHLRGPGAVAFARGLEANIFLKVLDISYNGFGDPGASAVGEALKANNVLEELNMSNNRISAMGALSLGLGLRVNQTLRILVVSRNPMRSEGCFGLLKSVQDNPASALELLDFSDIQVNAEFDGLASSVRGILPELCIKTGACR-VEYKKELLPVFRSALPASVPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PV94-1", "uniprot_id": "A0A8M1PV94_DANRE", "id": "A0A8M1PV94-1", "name": "", "aln": "-------MVAGKKVAKESVLPSVCEDEGDEGGQEEDLGGIASRPVSRPRSLYSRGSVDGQRVSRSSS----------------------LQHSISSGHQDEEQ-TTEDEDKNEDKGEGEQQQADKEDLDSDLELDTFHNIKQAYDHTGQSRYKEACKMLNVIPVSCFLRNINQSEVNMMHCGLGAQGTKALAISLVTNTSILKLNLRDNWMEGAGAAAIADMLKENCYITEIDLSDNRMGEYGARALSSMLLENSTLFSVNLSGNHLDERAAKHLSPALISNQKLQHLDLSHNRLTDTAGEILGAAIAENTGLKALNLAWNCIRGKGAIAFAKGLEGNIFLRSVDLSYNGLGKDGALALEEALKQNNTLEDLNISNNRIPFEGAVHLALGLKVNTTLRILKMSRNPIQSAGCFAILKSVQSNPESAAEFLDFSDICVDQEFEDLFNSTKETFPKLQVKHGGKMNAPFKRS---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . ::*:* . * ::. : .* ** : ..: : . * .:*: .*:*:* :**: . .*:*: * ***.** :*** * :* : :*:**** : **** *:*. * :.. * ::***:*::* * :*:.: * * :: .::*.** *:*:**:**: *: : *: ****:*:*.* *** **.*:******. **::** :** ** ***:***.****: :*:*:**:*. ** *: :**: **.**:**: ****. **: *.***:** ***:* :*:**: * **..:****:.* *. *:**.*.* *. * : * .* :* * :* : : ", "identical_positions": 152, "similar_positions": 111, "identity": "31.34%" }, { "cls_id": "homologset.agr.HGNC:34303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1W2Q6P1-1", "uniprot_id": "A0A1W2Q6P1_RAT", "id": "A0A1W2Q6P1-1", "name": "", "aln": "MVTSSKIMTERLLLTALKGGKSTKILTLNGKKMSKMPSALEKLPNLRTLDLQNNQISKVCPELRTLTKLTLLNLGNNLLQEVPEEIKYLTSLKNLHLFGNRICRIAAGVLDGLGDLVLLNLNDNQLSSLPPEIGRLQNLTFLSLNHNKLTVIPKEICFLEHLSELHINYNRITRIPEEIRFLQNLQQLSLVRNNIEELPEEVCQLTKLGVLDVAGNVIQIFPAGFQDLKLREFYCEGNPLFLKNPIFAPQPKDLWTLREIAARFVLSQLEEYNPLIMDAIECYPEVKDKLSKAKKCAICRKPFLSEWLECVYFVPPSKNWKISKNLQLIPLQTLVCSYQCFDRRDPDVFGIAKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9Q0-1", "uniprot_id": "LRC69_MOUSE", "id": "Q9D9Q0-1", "name": "Leucine-rich repeat-containing protein 69", "aln": "-------MAERLLVTALKGGKNTKILTLNGKRITKMPSTLEKLPNLKTLDLQNNSISKVCPELRTLTQLTLLNLGNNHLQEVPEEIKYLTSLKNLHLFGNRICRIAPGVFNGLHRLIMLNLNDNRLTSLPQEIGRLRSLTYLSLNRNNLTVIPKELCSLEHLSELHLNYNQIVYIPEEIKFLKNLQQLFLVRNNIEELPEEICHLEKLRVLDIAGNVIQIFPAGFQNLRLTEFYCEGNPLFLKRPFFAVQPKDLWTLREIAARFVLSLLEENDPLIMNVIESYPEVKDKLSKAKKCSICRKPFLTEWLECVYFVAPSKNWKISRNLKLIPVQTSVCSYQCFDQRDPDVFGIAQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNQ3-1", "uniprot_id": "LRC69_HUMAN", "id": "Q6ZNQ3-1", "name": "Leucine-rich repeat-containing protein 69", "aln": "-------MTERLLIKALSGGKNTKIITLNGKKMTKMPSALGKLPGLKTLVLQNNLIPKVCPELCNLTQLTTLNLGNNLLEEVPEEMKYLTSLKNLHLSGNRICRFAPGACDGLQNLILLNLNNNHLTQLPQEVSRLKSLTYMSINYNQLASIPRELCFLENLVELQLNYNQLICIPEEIKFLKKLQKLLLARNNIGVLPEELCDLKKLRILDIAGNIIQIFPSGFQDLKLREFYCEGNPLFLQQPVISTQQENVWSLQEITSRFVMNQLAENNPFLMDDIERYPQVRSMISQGKTCAICGQYFITVWLECVRFVPPPKDWKISKNLKLVPLQVLICSYKCFTQRDPNLFGIAQV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:****:.**.***.***:*****:::****:* ***.*:** **** *.****** .**:** ****** *:*****:*********** ******:*.*. :** *::****:*:*:.** *:.**:.**::*:* *:*: **:*:* **:* **::***:: *****:**::**:* *.**** ****:*.* ** :**:***:*****:***:*:* ***********:.*.:: * :::*:*:**::***:. * * :*::*: ** **:*:. :*:.*.*:** : *:: ***** **.*.*:****:**:*:*:*. :***:** :***::****: ", "identical_positions": 210, "similar_positions": 99, "identity": "59.32%" }, { "cls_id": "homologset.agr.HGNC:3431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62799-1", "uniprot_id": "ERBB3_RAT", "id": "Q62799-1", "name": "Receptor tyrosine-protein kinase erbB-3", "aln": "-------------------------------------------------------------------MRATGTLQVLCFLLSLARGSEMGNSQA------VCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGHN-ADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLKFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRVRGAEIVVKNNGA---NCPPCHEVCKGRCWGPGPDDCQILTKTICAPQCNG-RCFGPNPNQCCHDECAGGCSGPQDTDCFACRRFNDSGACVPRCPEPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTFCVRACPPDKMEVDKHGLKMCEPCGGLCPKACEGTGSGS-RYQTVDSSNIDGFVNCTKILGNLDFLITGLN--VDPWH------KIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYN-----RGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLR-----GPSEERLDIKYDRPLGECLAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNFLQGEPREFVH-EAQCFSCHPECLPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKG-PIYKYPDAQ----------------------------------------------------------------NECRPCHENCT---------------------------------------------QGCNGPELQDCLGQ---------------------------------------------------AEVLMSKPHLVIAVT--VGLAVILMILGGSFLYWRGRRIQNKRAMRRYLERG--ESIEPLDPSEK-ANKVLARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVKQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRA-SGPGTPPAAEPSVLTTKELQEAELEPELDLDLDLEAEEEGLATS-LGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSSLGEACLDSAVLGGREQFSRPISLHPIPRGRPASESSEGHVTGSEAELQEKVSVCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLE-EEDGNGYVMP------------DTHLRGASSS------------------------------REGTLSSVGLSSVLG-TEEEDEDEEYEYMNRKRRGSPPRPPRPG-------------------------------------------SLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDED-----YEYMNRRR----------GAGGAGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVRYAR---------LKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61526-1", "uniprot_id": "ERBB3_MOUSE", "id": "Q61526-1", "name": "Receptor tyrosine-protein kinase erbB-3", "aln": "-------------------------------------------------------------------MSAIGTLQVLGFLLSLARGSEMGNSQA------VCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGHN-ADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNGG---NCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNG-RCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTFCVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGS-RYQTVDSSNIDGFVNCTKILGNLDFLITGLN--GDPWH------KIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYN-----RGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLR-----GPAEERLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVH-EAHCFSCHPECQPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKG-PIYKYPDAQ----------------------------------------------------------------NECRPCHENCT---------------------------------------------QGCKGPELQDCLGQ---------------------------------------------------AEVLMSKPHLVIAVT--VGLTVIFLILGGSFLYWRGRRIQNKRAMRRYLERG--ESIEPLDPSEK-ANKVLARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRA-SGPGIPPAAEPSALSTKELQDAELEPDLDLDLDVEVEEEGLATT-LGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSNLGEACLDSAVLGGREQFSRPISLHPIPRGRQTSESSEGHVTGSEAELQERVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLE-EEDGNGYVMP------------DTHLRGTSSS------------------------------REGTLSSVGLSSVLG-TEEEDEDEEYEYMNRKRRGSPARPPRPG-------------------------------------------SLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDED-----YEYMNRRR----------GAGGSGGDYAAMGACPAAEQGYEEMRAFQGPGHQAPHVRYAR---------LKTLRSLEATDSAFDNPDYWHSRLFPKANAQRI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21860-1", "uniprot_id": "ERBB3_HUMAN", "id": "P21860-1", "name": "Receptor tyrosine-protein kinase erbB-3", "aln": "-------------------------------------------------------------------MRANDALQVLGLLFSLARGSEVGNSQA------VCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGHN-ADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNGR---SCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNG-HCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGS-RFQTVDSSNIDGFVNCTKILGNLDFLITGLN--GDPWH------KIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYN-----RGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLR-----GPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAH-EAECFSCHPECQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGAKG-PIYKYPDVQ----------------------------------------------------------------NECRPCHENCT---------------------------------------------QGCKGPELQDCLGQ---------------------------------------------------TLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERG--ESIEPLDPSEK-ANKVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRE-SGPGIAPGPEPHGLTNKKLEEVELEPELDLDLDLEAEEDNLATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGESCQESAVSGSSERCPRPVSLHPMPRGCLASESSEGHVTGSEAELQEKVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLE-EEDVNGYVMP------------DTHLKGTPSS------------------------------REGTLSSVGLSSVLG-TEEEDEDEEYEYMNRRRRHSPPHPPRPS-------------------------------------------SLEELGYEYMDVGSDLSASLGSTQSCPLHPVPIMPTAGTTPDED-----YEYMNRQR----------DGGGPGGDYAAMGACPASEQGYEEMRAFQGPGHQAPHVHYAR---------LKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD22-1", "uniprot_id": "A0A8M2BD22_DANRE", "id": "A0A8M2BD22-1", "name": "Receptor protein-tyrosine kinase", "aln": "----------------------------------------------------------------MKIMKMKSAMLQMIAMCLALRSPARAQTQEGKPEVGVCTGTQNLLSVTGSSEVQYKLMKEMYTGCQIVIGNLEITQMEHN-RDFSFLQSIREVTGYILIAINQFRRLPLEQLRVIRGTSLYEDKFALAVLVNYQKDGVYGLRELGLTHLTEILEGGVQIIQNKFLSYAPQINWQDIVKNSGAEVIIQDNGP---EVP-CHESCGGPCWGPGNDTCQILTKTVCALQCNV-RCFGRSPSECCHNECAGGCTGPLDTDCFACRNFNNSGSCVSQCPRADIYNKVTFKMEPNPNAKYQFGSMCVSHCPPNFVVDGSSCVSSCPADKMEVDKTGVKRCEKCEGLCPKACVGTGTGTASRQTVDSQNIDSFINCTKIQGSLHFLVTGIK--GDSYN------NISALDPKKLKIFNTVREITDILSIQSWPEELEDLSVFSNLATIQGRTLYRGVSSKRGYSLLVMKIPTLKSLGLRSLKRISDGGIYITGNTQLCYHHTVNWTRLFGSGPRALRRQKSLDIKENRPQEQCKLEGHVCDPLCSSEGCWGPGPDQCLSCKNFRRGGTCVPDCNFMSGEQREFAGPKNECMACHQECALQDSGDTCKGPGSDECKACAHLQDGPYCVSSCPEGVQGENGLIIYKFPNRQ----------------------------------------------------------------NKCQPCHANCT---------------------------------------------LGCLGPGQNDCVDS---------------------------------------------------SRSSAGLPVTAIVLSVIFCVLLAFSVFVLSVLYRRSLSIRRKRAMRRYLQSG--ESFEPLEPGEK-GVKVHARILRTSELKKIKLLGSGVFGTVHKGIWIPEGDTVKIPVAIKTIQDRTGRQTFQEITDHMLAMGSLDHAYIVRILGICPGASLQLVTQLSPQGSLLDHIRQRRDNLNPQRLLNWCVQIAKGMYYLEEQRMVHRNLAARNILLKSDLIVQIADYGIADLLYPDEKKYFFNEIKTPIKWMALESILFRRYTHQSDVWSYGVTVWEMMSYGAEPYSAMRPQDVPDLLEKGERLSQPQICTIDVYMVMVKCWMIDENVRPTFKELANEFTRMARDPHRYLVIKEEDRAPDSASDETHQNGTEIDILGVALEDQDDEVLEDAIDAP-RYITPSRSFSRLRIDSHR----SSLTPSTTAGYLPMTPG------LESSVQTGWASRSR------LDSACTVSESSEGRG-ALELEMNDDFSSVGSLRRVRH---REDSAYMSQRDSLSGPPETTSTGTQG-EEDQNEYVLPGFGESPEKETLLFTSSRSTLSQKRLSRGHSGDFLEANR-----GAGEEYEYMNNQTLSLSHIPGQLKEYNQRAPRNRSASFNPGGMYSNHKPSRPS---KRSSIEGSESSGGLSQSST--DQRSHSDGDFLSSEAEYTDGDLEVEYEYMDIRGAGGPAANMLLKLHLPRPVSNPPLRRSPEDDDEDEDYQYSNHQPRLRNSLRVQGGGGE-AYEYEDMDSLAAGGASGAEYQN--LDGEDEERDEDWSGGPRSPGPYVQVHAGTN--HNAFDNPDYWHSRSFHKTKAVRT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N4R3-1", "uniprot_id": "A0A8M1N4R3_DANRE", "id": "A0A8M1N4R3-1", "name": "Receptor protein-tyrosine kinase", "aln": "--------------------------------------------------------------------MGQQVLALCALLFLCVPQPVTSQTQE------VCTGTKNALSSTGTPEQHYNNLKERYTGCEIVMGNLEITQMEND-LDFSFLGSIREVTGYILIAMNQFRKLPLNQLRVIRGSSLYDKEWALSVFHNFDTH--TGLEDLGLTNLTEILEGGVQIVHNRNLSYAPLINWQDIVRDGDARIQIQDNGG---RGS-CNPACGEFCWGPSNDQCQKLTKTVCALQCLG-HCFGTNPNECCHPECAGGCTGPRDTDCFACRHVNYSGSCVPHCPWPVVYNQQTFQVEPNADAMYQFGSICVPKCPGHFVVDGSACVSSCPPGKTEIEKNQIKQCETCIGLCPKVCEGTGAN--HRQTVDSSNIDSFINCTKIQGSLHFLILGIK--GDVYN------NIPPLEPEKLKVFNTVREITGILNIQSWPDELHDLSVFSSLTTIQGRSLYN---PKRPFSLLVMKIPSLTSLGLRSLREISDGSVYITQNMNLCYHHTINWTQIF---PRNQLQRRRNDIKENKQKIQCEEEGHVCDPLCSDAGCWGPGPEQCLSCRNYSRLGTCVSHCNLYSGEPREFAASNKECLACHSECLLQNGKQTCLGKGADQCVACSNLMDGPHCVSSCPNGVNGEKGQTIFKYSTAA----------------------------------------------------------------GHCELCHFNCT---------------------------------------------RGCTGPALRDCVDP---------------------------------------------------DRNVNSSQIAGIAVAVFAGITVLLALFVLGMLYHRGLAIRRKRALRRYLESG--ESMEPLDPGEK-GTKVHARILKPQELRKGKLLGYGVFGTVNKGFWIPEGDSLKIPVAIKTIQNRSSRQTFTEITDHMLSMGSLDHPYIVRLIGICPGASLQLITQLSPHGSLLQHLRQHKDSLDPQRLLNWCVQIAKGMYYLEEHCMAHRNLAARNILLKSDYIVQISDFGVADLLYPDDKKYVYSEHKTPIKWMALESILFGRYTHQSDVWSYGVTVWEMMSYGAEPYASMHPHDVPGLLEKGERLAQPQICTIDVYMVMVKCWMIDENVRPTFKELASEFTRMARDPPRYLVVRPAQNGSGAEESQRYVKSSHLEVGLEEEDDDEDEGLQVGFATPPLQLSPTRSHSRVRIASYK----STSEHTAPIGYLPMTPG------PGDEPRQLRAQRRK------IGSVRTESECSEGRGTIVDIEAIEITSQTGSLRRGRS---RMDSAYISGGVSVASDP--FSPGLEGVDEDHYGYVLP-TERDFRSAVPHGRTSRNSKSTPKTDATQEYELMNKQTNKLSSSPTDSTDHLKPASLVSAHICSSLPQKKEMDSAQTQDEILPQKRETDSIQSQENNLPQKSETDSTQTQESEKDASFQPDNLESAENCLIGSETLNDGGQSEDEEQLPRLAMVEYEYMDIRTDEHQQN-VAGKRTTNGPNEVEREAIYQNISQPLRFHENPDSAGNTMQRRGEYVDMEASGRSGCEVGDYQNVPVKGRPVVGEESQNTGLRS---YIKVCAGVEPQNTSFDNPDYWHSRLFHKQDTVCT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04412-1", "uniprot_id": "EGFR_DROME", "id": "P04412-1", "name": "Epidermal growth factor receptor", "aln": "MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYS--KMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGE----CVPCNGPCPKTCPG-------VTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMES-----MFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQK------EPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYISN---AYKFDNRTCKICHPECR------TCNGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGD---------------KFTRLPAYTSQDEKDLIRKLAPTTD-------GSE----------------------------------------------------------AIAKPDDYLQPKAAPGPSHRTDCTDEMPKLNRYCKDPSNKNSSTGDDERDSSAREVGVGNLRLDLPVDEDDYLMP--------------------------------------------------------------------TCQPGPNNNNNMNNPNQNNMAAVGVAAG---------------------------------------------------YMDLIGVPVSVDNPEYLLNAQTLGVGESPIPTQTIG-------------------------------------IPVMGGPGTMEVKVPMPGSEPTSS-----------------------DHEYYNDTQRELQPLHRNRNTETRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: :* ** . ** .. : :*. : . * * * ***::. :: *:*** *******:*:: :. : : :*:::** ::. . : . : * :..* ::* * * : :* *.: *:* :** : . *: * *** . . ** ::* *: ** :*:* .* :*** *****:** :.**:**:.. .. . .** ** *: :*.*.. * :*. ** ** ::: * ** :** .* : * * * ***.* * .:.: ***.* *** * *.: :* :. * : . .*:*:: ::* **:***. *.*:. .:.::* * .* ** ** * . :: * : .: ** :*.*:.** * : * * :*** .:.*. : .. :: : * :* :*. *.. ****.*. ***:*:*: *.*:..*. .. : : * ** ** ** * *:* * * :. ** :**..**.. . .* .. .*. ** ** ** ** . . : : : : :: * .*.::: : . *. *** *.: . **.: **:* :** *.** * **.*:***:.:****.** : . :. :: . . :.* :* :::::.:* .:.: *:** * *.**:::::.: :..: **** .****** ****: :.**:** **::::: *:::*:*:*.** .*.:: * ****:***.* :* :****::***:**::::* .*: : ::*.*:* * :* **:**::*:* .::.** :* :*****:*:. *:.:**** ***.: . : : : * . * .: : : . : . . * . :*: . . . * *::* : : . : . * . : * . : : : ", "identical_positions": 306, "similar_positions": 323, "identity": "17.81%" }, { "cls_id": "homologset.agr.HGNC:3432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62956-1", "uniprot_id": "ERBB4_RAT", "id": "Q62956-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "--------------------------------------------------------------MKLATGLWVWGSLLVAARTVQPSASQS-----------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTIGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--------DPYNAIDAIDPEKLNVFRTVREITGFLNIQTWPPNMTDFSVFSNLVTIGGRVLYS-GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTVNQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DVLQG----------------------------------ANSFIFKYADQD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIMALTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK----FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGSQFVYQDGGFATQQGMPMPYTATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVVPH-VQEDSSTQRYSADPTVFAPERNPRAELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKA-EDEYVNEPLYLNTFTNALG-NAEYMKNSLLSVP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61527-1", "uniprot_id": "ERBB4_MOUSE", "id": "Q61527-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "--------------------------------------------------------------MKLATGLWVWGSLLMAAGTVQPSASQS-----------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--------DPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYS-GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYADQD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIMALTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK----FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMPYRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVAPH-VQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKA-EDEYVNEPLYLNTFANALG-SAEYMKNSVLSVP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15303-1", "uniprot_id": "ERBB4_HUMAN", "id": "Q15303-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "--------------------------------------------------------------MKPATGLWVWVSLLVAAGTVQPSDSQS-----------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--------DPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYS-GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYADPD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIVGLTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK----FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPH-VQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKA-EDEYVNEPLYLNTFANTLG-KAEYLKNNILSMP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZ77-1", "uniprot_id": "A0A8N7UZ77_DANRE", "id": "A0A8N7UZ77-1", "name": "Receptor protein-tyrosine kinase", "aln": "--------------------------------------------------------MDMQPLHTNKMRSDILIALFLTAVIVPLCTSQS-----------VCPGTDNKLSTLSDLDQQYKTLRKFYENCEVVMGNLEITSIER-NRNLSFLKSIREVTGYVLVALNQFDYLPLENLRIIRGTKLYEGRYSLAIFLNYRRDGYFGLRQLGLKNLTEILNGGVYVDQNKFLCHADTIHWHDIIKNPRSELLVVPSNNSGNTCRRCHRSCNGRCWGHQEDQCQSLTKTVCAEQCDG-RCFGPYVSNCCHRECAGGCFGPKDTDCFACTNFNDSGACVTQCPQPFVYNPTTFQLEHNPNAKYTYGAFCVKKCPHNFVVDHSSCVRACPSNKMEVEENQTKMCIPCTDICPKVCDGIGTGSLQMAQTVDSSNIEKFVNCTKINGNLIFLITGIKG--------DMFHGIRALDPDRLNVFRTVREITGFLNVQSWPENMTDLGVFSNLATIGGRSLYS-GISLLILKQRWITSLQFQSLREISAGNVYMTNNSQLCFYSTVNWTSLFRTSTQRALIKNNREPRECSKEQKICDPLCSEAGCWGPGPDQCLSCKYFSRGKTCVKSCNLYYGDVREFANGSVCVECDSQCEKAGEKGLTCHGPGPDHCVKCLHLKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYAETN--------------NECHPCHPNCT---------------------------------------------QGCTGPRIQDCVG-------------------------------------ILDRTPLIAAG------------------LIGGLFVIVIIALGVAVYIRRKSIKKK----RALRRFLETELVEPLTPSGAAPNQAQLRILKETELKRVKILGAGAFGMVYKGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHQDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLDTDEKEYNSDGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTRDIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNHST----FFKSLLDEEELDDLMDADEYLVPQTCNISTSTYTSRTTMDASWT-LRCRD---------RVFSPEDGMGACSRDVPASASAVFVPV----STQAAGLNVLEEQHCNGSLKKQQPMSGSGDDCDGQRYSADPTVFLGERSLKN-TDEDGYMSPMN-KSTSDHLSPVEENPFVNHRKNGNITALDNPGYHSTPDKKSKAEEDEYINEPLYLNAYNTTGGTNLEIMRRNGSSIPLQMTTATSAASSHIILSTQPGKAHHHGQGTHVHFAIPPVQPPQTRAMSQNGQHSQSSHAVESNSSSMSANPSLLSQISLVSQQIQPCLASQSQVPKSTVPNKSISGLPGHLVYPVNMLQTGHTGTVMADRKSKKNFDNPDYWQHSLPPKVTQANPQDPTQTCKSKHLYRHSIRSRLAVADNPEFVSEFNKRPGPVLPPPPYRHRNTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q7Y5-1", "uniprot_id": "A0A8M9Q7Y5_DANRE", "id": "A0A8M9Q7Y5-1", "name": "Receptor protein-tyrosine kinase", "aln": "---------------------------------------------------------------MWPVRFLLLFCLVFTFAVLQRSSGQS-----------VCPGTDNKLSTLSDLDQQYKTLRKFYENCEVVMGNLEITSIER-NRNLSFLKSIREVTGYVLVALNQFDYLPLENLRIIRGTKLYEGRYSLAIFLNYRRDGYFGLRQLGLRNLTEILNGGVYVDQNKFLCHADTIHWQDIIKNPRSELLVVPSNNSGNTCRRCHRSCNGRCWGPQEDQCQSLTKTVCAEQCDG-RCFGPYVSNCCHRECAGGCFGPKDTDCFACTNFNDSGACVTQCPQPFVYNPTTFQLEHNPNAKYTYGAFCVKKCPHNFVVDHSSCVRACPSNKTEVEENNIKMCIQCTEICPKMCDGIGTGSLQSAQTVDSSNIEKFVNCTKINGNLIFLITGIKG--------DMYHGIRALDPERLNVFRTVREITGYLNIQSWPENMTDLSVFSNLVTIGGRTLYS-GISLLILKQRWITSLQFQSLREISAGNVYMTNNSQLCFYSTVNWTSLFRTSTQKAKIKDNRDPRECSQQRMVCDPLCSVSGCWGPGPNQCLSCKYFSRGRTCVRSCNLYNGDVREFANGSTCVECDSQCEKAEDKSLTCHGPGPDHCVKCLHLKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYPETN--------------NECHPCHPNCT---------------------------------------------QGCTGPRIQDCIG-------------------------------------ILDRTPLIAAG------------------VIGGMFVVVIVALGFAIFFRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKILGTGAFGTVYKGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHQDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLETNEKEYSADEGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNHSK----FFQSLLDEEELDDLMDADEYLVPHSLNAPPTSHIPHPHVDSNQNQFGYHD---------GSRCPEDVT--RFHEVAAAGNAPSALG----SAQRAGLDLVEEQHCNGSLKKQATVH-SVEDSSGQRYSADPTVLLGEKTQREDTDEDGYMSPMKDKISTNHLNPVEENPFVTRRKSKDVHALDNPGYHNTPDGKPKC-EDEYINEPLYLNTFNNTSDIHQEMLRKNGVSIPAQMTTAG-----HILQT---GKPHHHSHGPHVHFAIPPVQPVHPGPMSQNDHN---AHSVQSGHDHAVKSGPSAGQICLVSHQVQQGHPSKSNRSPQQFQLSGGK-LPGHPVQPG-----SQIGTVLVDKMYKNSFDNPEYWQHSLPP--PQISQDSSSAVCNNKFLYKQNGRVQPPAAENPEYLSGVK--PGMVLPPPPYRQRNTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04412-1", "uniprot_id": "EGFR_DROME", "id": "P04412-1", "name": "Epidermal growth factor receptor", "aln": "MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVT--YSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGE----CVPCNGPCPKTCPGV--------TVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYIS-NAYKFDN-RTCKICHPECR-------TCNGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAKPDDYLQPKAAPGPSHRTDCTDEMP---------------KLN--------------------------------------------RYCKDPSNKNSSTG------DDERDSSAREVGVGNLRLDLPVDEDDYLMPTCQPGPNNNNN-------MNNPNQNNMAAVGVAAGYMDLIGVPVS-----VDNPEYLLN-AQTLGVGESPIPTQTIGIP--------------------------------------------------------------------------------------------------------------------------------------VMGGPGTMEVKVPMP-------GSEPTSSDHEYYNDTQRELQPLHRNRNTETRV--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . : . . :* **..:** *: :::*: **. * ** * ***::* : . * :**** .:******:*:: :. : : :*:**** .*:. : : : * : :* ::*** * ..:* **: **:* :*: * . * :**.**. *** .:**.::: .*: ** * **:** :*** ***** **.:.**:** ** *.... :** *****: ** * :.**:*** ***:** ::: * .:***:**..* : : * *. *** * *: .:.:.**:.* *** *:**: :* : * .:**:: :** **:****:**:: :: ::. * ** ** ** * . :: * : : : **:::.*::**:*.: : .* :**: .:.*.:: *: :.:* . * : :*. *. ****.*.:***:*: *. . *: .*. : :* * * *..:*. **:*.*.*:* :* *.:** :**.:** * * .:.::::* . : .:*** ** :**.** .** * **. : *.::: .* * .. :. *:. * * : : * *** **. ..* .:***:*::**:: :** **** ****:******.******** * ::**.::. **: ** **** :* :*::**.**:*. : *:***** ****:**::::*:***: ****..****** ****:**************::*. :********:**. :.:**.: *******:*****: * ** :****::*******:*** :*::.**:::***::* * :* ** **::*:* .::.** :** ** **:*:: *:.:**** ***.* **. :**: . . : : : : : ..::** *:: .. : *:.. .* . :* *: * : **:.*: * : . :.. :. :: *:. . : . . :::* ** : . . : . .:* :..* : .:* . . : *... * * : : . ", "identical_positions": 420, "similar_positions": 353, "identity": "24.88%" }, { "cls_id": "homologset.agr.HGNC:3433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07992-1", "uniprot_id": "ERCC1_HUMAN", "id": "P07992-1", "name": "DNA excision repair protein ERCC-1", "aln": "MDPGKDKEGVPQPSGPPARKKFVIPLDEDEVP-PGVAKPLFRSTQSLPTVDTSAQAA-PQTYAEYAISQPLEGAGATCP---TGS-EPLAGETPNQALKPGAKSNSIIVSPRQRGNPVLKFVRNVPWEFG-----DVIPDYVLGQSTCALFLSLRYHNLHPDYIHGRLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLTTFGSLEQLIAASREDLALCPGLGPQKARRLFDVLHEPFLKVP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07903-1", "uniprot_id": "ERCC1_MOUSE", "id": "P07903-1", "name": "DNA excision repair protein ERCC-1", "aln": "MDPGKDEESRPQPSGPPTRRKFVIPLEEEEVP-CAGVKPLFRSSRNPTIPATSAHVA-PQTYAEYAITQPPGGAGATVP---TGS-EPAAGENPSQTLKTGAKSNSIIVSPRQRGNPVLKFVRNVPWEFG-----EVIPDYVLGQSTCALFLSLRYHNLHPDYIHERLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILADCTLVLAWSAEEAGRYLETYKAYEQKPADLLMEKLEQNFLSRATECLTTVKSVNKTDSQTLLATFGSLEQLFTASREDLALCPGLGPQKARRLFEVLHEPFLKVPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GI31-1", "uniprot_id": "A0A8I6GI31_RAT", "id": "A0A8I6GI31-1", "name": "DNA excision repair protein ERCC-1", "aln": "--PG--KASGRRVVRVRGGGGFQCPFPTPNSPFSSQAKPLFKSSRNPTPTAASTHSA-PLTYAEYAIAQPPGGAGATVP---TGS-EPATGDSPSQTLKAGTKSSSIIVSPRQRGNPVLKFVRSVPWEFG-----EVTPDYVLGQSTCALFLSLRYHNLHPDYIHERLQSLGKNFALRVLLVQVDVKDPQQALKELAKICILADCTLVLAWSAEEAGRYLETYKAYEQKPADLLMEKLEQNFLSRATECLTTVKSVNKTDSQTLLTTFGSLEQLITASREDLALCPGLGPQKARRLFEVLHEPFLKVPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7KMG7-1", "uniprot_id": "Q7KMG7_DROME", "id": "Q7KMG7-1", "name": "DNA excision repair protein ERCC-1", "aln": "-------------MEDFDDDSFNDVLGAMEMP--------------------TAAKQ-PKVDAPAATAVNPAPSNSTEP---SGSGRPAPG-------KPASNPHCVLVHSKQRGNPILKSILNVPLEFRD----DIVPDYVVGRTSCVLYLSLKYHNLNPDYICQRLKALGKMYELRVLLVQVDTPEPNNALKSLTRISLLADLTMMLAWNAEEAGKIIETYKQFEKRPPDLIMERVESNPHQKLLAALTNIKPVNKTDAAALLHTFGNLGNIINASEERLSQVMGLGPRKAKKLYKTLQEPFLSK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06838-1", "uniprot_id": "RAD10_YEAST", "id": "P06838-1", "name": "DNA repair protein RAD10", "aln": "-------------MNNTDPTSFESILAGVAKLRKEKSGADTTGSQSLEIDASKLQQQEPQTSRRINSNQVINAFNQQKPEEWTDS-KATDDYNRKRPFRSTRPGKTVLVNTTQKENPLLNHLKSTNWRYVSSTGINMIYYDYLVRGRSVLFLTLTYHKLYVDYISRRMQPLSRN-ENNILIFIVDDNNSEDTLNDITKLCMFNGFTLLLAFNFEQAAKYIEYLNL------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . * . . * :.* .. . :. ::* . *: **:*: : .. .: :: : : ..*:*:* **:* *** *::.*.: .:*:. ** :.:::*:.::::.:: . *::**:. *:*.: :* : ", "identical_positions": 30, "similar_positions": 64, "identity": "9.71%" }, { "cls_id": "homologset.agr.HGNC:34332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7AIG4-1", "uniprot_id": "F7AIG4_MOUSE", "id": "F7AIG4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------EKPYECNQCGKAFSCHNSLIYHKRTHTGEKPYECNQCGKAFARPAHLHRHKRTHTGEKPYECNQCGKAFS----------CHSG------------------LRYHKSTHTGE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2P0-1", "uniprot_id": "ZN835_HUMAN", "id": "Q9Y2P0-1", "name": "Zinc finger protein 835", "aln": "MEGLLSVALQGAELEGNWKHEGQVEDLQENQESCPEPEAVACKGDPAGDSMQERDEFSRIPRTISSPAATQASVPDDSSSRRCSAPGESPKERHPDSRQRERGGGPKKPWKCGDCGKAFSYCSAFILHQRIHTGEKPFACPECGKAFSQSVHLTLHQRTHTGEKPYACHECGKAFSQGSYLASHWRTHTGEKPHRCADCGKAFTRVTHLTQHRRVHTGERPYACAQCAKAFRNRSSLIEHQRIHTGEKPYECSACAKAFRFSSALIRHQRIHTEEKPYRCGQCAKAFAQIAHLTQHRRVHTGEKPYTCQDCGALFSQSASLAEHRRIHTGEKPYACGQCAKAFTQVSHLTQHQRTHTGERPYPCHDCGKRFSNRSHLLQHRLVHTGERPYRCLQCGAAFSHVSSLIEHQKIHTGERPYKCGECGKAFSQGSSLALHQRTHTGERPYTCPECGKAFSNRSYLIQHHIVHTGEKPYECSGCGKAFSFSSALIRHQRTHADSSGRLCPAPTPDSTPGLSQGGETCQQGCPGRNPRGPAED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**::*.:****** .::* *:* ******: * :*****::..** *:********* *::****** *:* * *: .**** ", "identical_positions": 51, "similar_positions": 21, "identity": "9.5%" }, { "cls_id": "homologset.agr.HGNC:34333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2I4-1", "uniprot_id": "A0A0G2K2I4_RAT", "id": "A0A0G2K2I4-1", "name": "", "aln": "MDASFFPESLFSDDQICSQEEETEGESTLGEDCDKDEAVDCAQEEWTLKDPTQSSRPGDVAVEDHTNLATAELEKQLQTKDSAPEQDFLARHTFMETQQVDAVTFEDVAVDFTQEEWTSLDPIQRTLYREVMLENYQ---------------------------------------------------NLATVGGQLFKPSLISWLERKVELTVMEQGILQEWEMHLKTKRTALQQDRFWSDMSNG---MQLGRELSGGELGDSIQVGTVFSEDSCPQTYISTPSTEDTSACHLRGKDFLPPLKETSTEENILQLNQCVKPLTLTPDVS--QRMCTLEKSVECSDCGKTFVNELELQAHSSSHSENNLHKPEECGQAFTHPVSHDGHVIP-TEKKYYECKKCEKFFTHPVY---LNIHVQSHTVEKPYDCKECGKAFTERSSLIVHLRQHTREKSYECKECGKTFIQPSRLTEHMRSHTGEKPYQCDQCGNAFASSSYLTTHLRTHTGEKPFECNICGKAFTRSSYLLGHIRTHTGEKPYECKVCGKAFSGRSWLTIHLRKHTGERPYPCTECEKAFTSFAQLTEHIKTHTGEKPFRCKVCARTFRNSSCLKTHFRIHTGIKPYKCNYCGKDFTARSGLTKHVLIHNGEKPYECKECGKAFSTSSGLVEHIRIHTGEKPFECYQCGKALAHSSSLVGHLRTHTGEKPFECNQCDKTFTRSSYLRIHMRTHTGEKPYECKECGKTFPERSCLTKHIRTHTGERPYECKECGKGFISFAQLTVHIKTHSSERPFQCKVCTKSFRNSSSLETHFRI-HTGVKPYKCSYCGKDFTARSGLTIHLRNHTGEKSYACQECGKAFSTSSGLIAHIRSHKGEKPFECDHCGKAFASSSYLNVHLKIHTGEKPFQCTVCGKTFTCSSYLPVHMRTHTGEKPFQCIICGKSFLWSSYLRVHMRIHTGEKPYVCQYCGKAFTEHSGLNKHLRKHTGEKPYEYKDSGEAFTTSTDANEHETPHWGENL-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10076-1", "uniprot_id": "ZFP26_MOUSE", "id": "P10076-1", "name": "Zinc finger protein 26", "aln": "----------------------------------------------------------------------------------------------METQQVDAVTFEDVAVDFTQEEWTSLDPVQRNLYRDVMLENYQ---------------------------------------------------NLATVGGQMFKPSLISWLEKKVELTVIEQGILQEWEMHLKTKRTALQQDRFWSDMSNG---MQLGREHSGGEPGDPVQVGAVFSEDSCPQTHSSTSNTGNTFACNLDGKDFQPLLKETSTEENIVQLNQCVKPLIFTPDVS--QKKCTPEKSVECSDCGETFVNQLELQTHSSSHREKNIHKSEECGQASTHPISHGGHVIP-TEKKYYECKKCEKFFTHPVY---LNIHMQSHTVEKPYDCKECGKAFTERSSLIVHLRQHTREKSYECKECGKTFIQPSRLTEHMRSHTGEKPYQCDQCGNAFASSSYLTTHLRTHTGEKPFECNICGKAFTRSSYLLGHIRTHTGEKPYECKVCGKAFSGRSWLTIHLRKHTGERPYPCTECEKAFTSFAQLTEHIKTHTGEKPFRCKVCARTFRNSSCLKTHFRIHTGIKPYKCNYCGKAFTARSGLTKHVLIHNGEKPYECKECGKAFSTSSGLVEHIRIHTGEKPFECYQCGKALAHSSSLVGHLRTHTGEKPFECNQCDKTFTRSSYLRIHMRTHTGEKPYECKECGKTFPERSCLTKHIRTHTGERPYECKECGKGFISFAQLTVHIKTHSSERPFQCKVCTKSFRNSSSLETHFRI-HTGVKPYKCSYCGKAFTARSGLTIHLRNHTGEKSYACQECGKAFSTSSGLIAHIRSHKGEKPFECDHCGKAFASSSYLNVHLKIHTGEKPFQCTVCGKTFTCSSYLPVHMRTHTGEKPFQCIICGKSFLWSSYLRVHMRIHTGEKPYVCQYCGKAFTEHSGLNKHLRKHTGEKPYEYKECGENFTTSADANEHETPHWGENL-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARR7-1", "uniprot_id": "A2ARR7_MOUSE", "id": "A2ARR7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MDLVTYDDVQVNFTQEEWALLDPSQKSLYKDVMLETHR---------------------------------------------------NLTAIGYIWEE---------------------HTIEDHFQ---------------------------------------------------------TSRSHG----------RHERSCSAEQPSEFIQCGKAF--------------------------AYESHS--QRYEIKH----------------------------TGEKHHDCNQCGKAFARSDD---LQKHKRTHTGEKPYKCNQCGKSFA-----------RSGD---------------------------------------------LQKHKRTHTGEKPYECNQCGKAFARNCDLQKHKRTHTGEKPYECN--------------------------------------------------------QCGKAFARKCDLQKHKRTHTGEKPYECKQCGKAFAESSTLQIHKRTHTGEKPYECNQCGKAFKRSSDLQKHKRTHTGEKPYECKQCGKAFAESSTLQIHKRTHTGEK----------------------------PYECNQCGKAFKRSCELQKHKRTHTGEKPYECNQCGKAFKRSCELQKHKRIHTGEKPYKCNQCGKAFTQSSHLQIHKRT-HTGEKPYECNQCGKAFARNCDLQKHKQTHTGEKPYECNQCGKAFARKCDLQNHKQKHTGEKPYECKQCGKAFAQSSHLRIHKRTHTGEKPYECNQCGKAFK----------------------------RRSDLQVHKRTHTGEKPYKCKQCGKAFARSGGLQKHKRTHTGERPNECN-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AU83-1", "uniprot_id": "A2AU83_MOUSE", "id": "A2AU83-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MGRVTYDDVHVNFTREEWALLDPSQKNLYRDVMLETYR---------------------------------------------------NLAAIGYVWED---------------------HNTEEHLH---------------------------------------------------------ISRRYE----------RHERSHTAQQLSEFIQCDKAF--------------------------AFQSHN--QRKEKIH----------------------------NAETPYECNQCGKSFARKSH---LLRHKRIHTGEKPYACNQCGKDFASPSYLQYHKRVRTGEKPYKCNQCGKAFACSTGLRGHKRTHTEEKLNECNQCDKAFAGQSGLLYHKRTHTGEKPFQCNQCGKTFARNTHLLQHKRVHTGEKPYECNQCEKASVCHIGLLYHKRTHAGQRPYECNECGKSIVYHSCIKQCKRRHTGEKPFECNQCGKSFARKSHLLRHKRIHTGEKPYKCDQCGKDFARPSSLQYHKRVHTGEKPYECKQCGKAFACSTVLRRHKRAHTGEKPFECYQCGKSFASKSHLLRHKRIHTGEKPYKCDQCGKDFVYHSCIKQCKRRHAGEKPFECNQCGKSFASKSYLLRHKRIHTGEKHYKCDQCGKDFASTYSLQNHKRVHTGEKPYECKQCGKAFACSSKLRSHKRT-HTGEKPFECNQCGKSFAIKSHLLRHKRIHTGEKPYKCDQCGKDFARPSSLQYHKRVHTGEKPYECKQCGKAFACSRRLRIHKRTHTGEKPYECNQCGKAFSSPSGFLYHKRTHTGERPYECNECGKSFIHRSNFQMHKRTHTGEKPFECDQCGKSFAQNTYLLQHKRVHTGEKPYECKHCGKAFAYSNKLRVHVRTHTK----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8JJZ4-1", "uniprot_id": "B8JJZ4_MOUSE", "id": "B8JJZ4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MNAVTYRDVHVNFTQEEWALLDPSQKKLYKDVMLETYR---------------------------------------------------NLNAIGFNWEA---------------------QNIEEHCQ---------------------------------------------------------SSRRHR----------RCERSQSAEKPSEYTQRDKAF--------------------------ALRAHSHAQRHERIHTEKIPSEDIHCVEDVLPYTSLQVHKRTQTGQKPYECKQCGKGFAKPSH---LKRHERFHTVEQPFICNECDEVFSFKHHLQTHIRVHTGEKPFKCNLCDKSFSKHNHLQSHRRTHTGEKPYKCDQCDKAFSEKCNLQTHIRIHTGEKPYKCDQCDKTFSEKCHLQKHIRIHTGEKPYKCNQCDKAFSQYSTLQTHRRTHTGEKPYKCNQCDKAFSQYGNLQTHRRTHTGEKPFKCNQCDKAFSQYSTLQTHRRTHTGEKPYKCNQCDKAFSEKCSLQRHIRIHTGEKPYKCNQCNKAFSHNYHLHIHRRTHTGEKPYKCNQCDKAFSIHFPLQNHKRTHTGEKPYKCNQCDKAFSEKCHLQNHIRIHTGEKPYKCNQCDKAFSQYFSLQTHRRIHTGEKPFKCNQCDKAFSQYSTLQTHRRTHTGEKPFKCNQCDKAFSKHSTLQSHRRT-HSGEKPFKCSQCDKAFSQYNTLQAHRRTHSGEKPFKCDQCDKAFSEKCNLQKHIRIHTGEKPYKCNQCDKAFSQYNTLQTHRRIHTGEKPFKCNQCDKAFSRHSTLQTHRRTHTGEKPFKCNQCDKVFSQYSNLQTHRRTHTGEKPYKCDQCDKAFSMKCNLQNHVRIHTGEKPYKCNQCDKAFFQYSNLHIHRKTHTGQKPYKCNQ--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNA1-1", "uniprot_id": "ZN836_HUMAN", "id": "Q6ZNA1-1", "name": "Zinc finger protein 836", "aln": "-----------------------------------------------------------------------------------------------MALTQGPLTFRDVAIEFSQEEWKSLDPVQKALYWDVMLENYRNLVFLGILPKCMTKELPPIGNSNTGEKCQTVTLERHECYDVENFYLREIQKNLQDLEFQWKDGEINYKEVPMTYKNNLNGKRGQHSQEDVENKCIENQLTLSFQSRLTELQKFQTEGKIYECNQSEKTVNNSSLVSPLQRILPSVQTNISKKYENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYN---LAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNLVNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRN-PTGEKPHKCSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNECGKVFRHQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPYKCNECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECGKSFISRSGLTKHQTKHTAESLKTKFNVEKPLDVLLTSGFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LFR7-1", "uniprot_id": "A0ABK0LFR7_RAT", "id": "A0ABK0LFR7-1", "name": "", "aln": "------------------------------------------------------------------------------------------MAGFPVNTFQGLLTFRDVAVDFSSEEWECLDSAQRALYIGVMLENYS---------------------------------------------------NLVSVG-IVCKT---------------------DLVPCLEQ--------------------------------------------------------ICMPWK---------VKREKMVTKPGREKHQVCSESE-------------------------KVLDQDSKSIIYEYVD----------------------------MQWKSSECNELGKMLQESSR-WILCKANNTPEICNKYRFGNYGDACFESPNLSRHKSIHTGEEPFKYKDYGKSLSLFSNVSQSHGIYIGEKEYK--ECDKTFG-STPKLVQLKIHSGENPR-----RTGFRTCSSLSTYQRTYTGEKPWICTEYNKVFRWLSDLKTHYRVHPGEKPFKCKEWDKSITFCSSLREHENLHEG-KLYKCLECDKSFTRCSSLRAHGKIHTGEKPFKCKECIKSFYMFSQLRKHARIHTGEKPYKCKECEKSFTYSSSLREHQNMHAG-KLYKCQECDKSFTRCSSLRAHEKIHTGKKPFKCKECGKSFYMVSQLRKHARTHTGEKPYKCKECEKSFTQCSTLRIHQKIHAGEKPYKCKECGKCFYKLSYLKVHYRTHTGEKPYQCNECGKGFSQLSCLKSHERI-HTGEKPYKCNECDKSFAHCSTCRRHQSTH-AAKLYKCGECDKSFAKYSSLRTHQKVHAEEKPHACKECGKAFYQLSHLKVHYRIHTGEKPYKCDECEKSFTKCSSLRTHQKIHTGEKPHACKECGKAFYHLAHLNIHYRIHTGEKPYKCSECDKSFTTLANLRRHHKIHPGKKPFHSK-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PWT2-1", "uniprot_id": "E9PWT2_MOUSE", "id": "E9PWT2-1", "name": "", "aln": "------------------------------------------------------------------------------------------MAGSPVNTFQGLLTFRDVAVDFSQEEWECLDSAQRALYIGVMLENYS---------------------------------------------------NLVSVGIIVCKA---------------------DLVPHLEQ--------------------------------------------------------IYIPWN---------VKIKEMVAKPGRESYRMCSESE-------------------------IVFYQDSKNIIYEHVD----------------------------IQWKSSECNEIGKMLHESSGGWILCKTNNTPEICNKYRFDNHKDAYIESTNLSRHKSMHTEEEPCKYKDYGKSLSLFSNVSQSHGIYIGEKEYK--ECDKTFG-SFPKLVQLRIHSGKNPQKCRKCRTGFRTCSSLSTHQRTYTGEKPWICTECDKAFRWLSDLKTHYRIHPGEKPFKCKECDRSFTFYNSLREHQNIHKG-KLYKCWKCDKFFTRCSSLRAHEKIHTGEKPFKCKECIKSFYMLSQLRKHARTHTGEKPYKCKECDKSFTYSSSLREHQNMHAG-KLYKCQECDKCFTWCSSLRAHEKIHTGEKPFKCKECGKSFCMLSQLRKHARTHTGEKPYKCKECEKSFTQCSTLRIHQKIHAGEKPYKCKECGKCFYKLSYLKVHYRTHTGEKPYQCKECGKGFSQLSCLKSHERI-HTGEKPYKCSECDKSFTHCSTCRRHQSTH-AAKPYKCEECDKSFAKQSSLRTHQKVHAGEKPHACKECGKAFYQLSHLKVHYRIHTGEKPYKCDECEKSFTKCSSLRTHQKIHAGEKPHACEKCGKAFYHLSHLNIHYRTHTGEKPYKCSDCDKSFTTLANLRRHHRLHTGEKTFHSK-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VGR8-1", "uniprot_id": "Q9VGR8_DROME", "id": "Q9VGR8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MRCAVPNCRNFSDCRSKRNAAQQQRLGFFRFPKCPDTFK--------------------------------------------------AWLAFCGYTEES-----------------------------------------------------------------------------------------------------LKLKNPCICIEHFKDEDIEGSL--------------------------KFEMGLAKKRTLRPG----------------------------AVPCVNKSQESGSDRARKER----SQRRRNQELVAELLAEEEAKLIHPEATSFEQDSVYLSET----------------------------------------VTMELDPLSGEEKLEELQKCRTCYNDFTADFRAKDLFDPANSVLLFHIEVISGVWISHK---------PDEPRLMCPACKSALDQAIDFR------------------EMCISTELKLSQAKPSTDEVQIEAENENPISSDHDLISDTENTNVEEIEDAGGDHVEDEATSDDQTSQEAVDEVAESPAAQDPLSVALGAKIFKELLDQYTGKEKARLRKGAPIAS-----KPKAKEKAAGEQKPKRSANPKTKEERNLIRRAQLRAKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRNMHIRIRHRGETPFACGFCSETFAYPGARQKHESEVHNAAP-------RLIVKRINPKPMPKPRESVR-YQCKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTHE-KRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCEVCNVNFRYKYNMKSHANSKMHQDNARKLGVVQIVATE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : :. : : :.. * :. . ..:: . . . : . : .. :: . * .. : . : * :. : : * : . : . : . : . : :**:: ... * : : :: : *.:*.: : * * *: : ::*. * : * * .*. *. *.. *: * : : . : : : . *. * * : * * **. :.: * * *:: : : * ****:*: * *. * : * : : . ", "identical_positions": 41, "similar_positions": 98, "identity": "3.96%" }, { "cls_id": "homologset.agr.HGNC:34336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M6Z6D8-1", "uniprot_id": "A0A8M6Z6D8_DANRE", "id": "A0A8M6Z6D8-1", "name": "", "aln": "----------------------MMSEFPESSD--SEFPYSFSADGRLRHTHTGEP----YRFQFHLR-DALQTETEQRRLCRFLTQHVYTLLQQNFQMR----------LEEHCSVFMTPGALE-HAGCLLLLLQDRGTVRGGLWSWKITAHEGLETGSQIPYLRWALMENYAVIIMNPNGDLHN-------------------------------------------KTPEEHVSEVWRRLVCVSAAQHVFVVAHGYGGLAFVDLLCCRMEEVQRRVTAVAFLDSSHSLWHQP-LGKAGRDWLRCHSRTWILSTKALNRSVG-SLKAGCTQISAGTQCHDSAPAVCMESVFRFFSKTIKPKATPTPFEIITRSRSRSHDHNNNNKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A6NC97-1", "uniprot_id": "ARB2P_HUMAN", "id": "A6NC97-1", "name": "Putative protein ARB2BP", "aln": "-----------------MTQELSFQKFIEQSDLLGELKYDFNEKDEFRHTETQRP----FVFNYYEN-VLEKNSKRYQALGHLLEQYIYELLEKVCKLEKVYIPPEADKEEPRSFFFMSEKALTNHHSALLILLQDHGVFRAGQWSQQAIIHHGLQHGSQIPCIQMALQAHYDVIVLNPNDNFVEPKVEKEWKGLLTQNIESSSLKMVQGGSFFSLQHPPKCIPKRCSNTPEEHTAYIWDYFISKTEGKDIAFIVHGYGGLVFMDLLVRRRWEVMSKVYAVALIDSEHHVGHQLGSDVQLLAWIKHHCREWVTSPKPLDKPAATVFKKEFPMVSAGTEKYILAPSSSLQSIFKYFKKALKARTTINFSRMPIVTRSSTKRKQSA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95RN0-1", "uniprot_id": "F172A_DROME", "id": "Q95RN0-1", "name": "FAM172 family protein homolog CG10038", "aln": "MWSRLIQIFRPLRSFRMSHSPPPASNCEEALIQLKNFGYAFDGEGVLRKVDPATGEPGKELFSYNVSDDAAENEKHYQKLANQIPEIVYALLEKNGLSRTYIP---FDQPPERSSFVFSQPAKLSQSKKLLVLIHGSGYVKAGQWARSLIINNSLDHGTQLPYVRQAQKLGYDLLITNANDCTRFYNGKEN--------------------------------PIKGVNTSVEHVKYVWKNIVLPAKPESVAIVAHSYGGSLTLDLVERFPDFFKESVFAIAFTDAAMGSPQAK-----NKEYLCDVACDWVASNTPLDTPVS-QSKSSIRRISAGHTKHEWTSYSAIDSVFKFIEEKYEQRANKK---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * :: * *. .. :*:... *.: :.... : * . : : :* **:: . :. ..:: * : **:*::. * .:.* *: . :..*: *:*:* :: * * ::: *.*. :*. **. :* :: : : : .:.*.*** :**: . * *:*: *: : :: . *: * ..*: ... * :*** : :. .::*:*:::.: : ::. . ", "identical_positions": 47, "similar_positions": 104, "identity": "12.14%" }, { "cls_id": "homologset.agr.HGNC:34339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K064-1", "uniprot_id": "F174B_MOUSE", "id": "Q8K064-1", "name": "Membrane protein FAM174B", "aln": "MSALPPQPPPPLLLLLLALLAAPAALARRAESASASQPEAEHQP--PPGPG--NATQLGSGMAGGGSS---NSSVDAVVTRISSLLRDLPTLKATVIVACAFSALLIACLLLRVFRLGKRLKKTRKYDIITTPAERVEMAPLNEEDDEDEDSTVFDIKYR------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPV2-1", "uniprot_id": "A0ABK0LPV2_RAT", "id": "A0ABK0LPV2-1", "name": "", "aln": "MSALPPPPPLPLLLLLLVLLAAPAVLARRAESASASQPEADHQS--PPSPG--NATQLGSGMAGGGGS---NSSVDAVVTRISSLLRDLPTLKATVIVACAFSALLIACLLLRVFRLGKRLKKTRKYDIITTPAERVEMAPLNEDEDEDEESAVFDIRYSILAVLGQRSGFQCLGLDESLKVIGTQPYDSSANVSNGDTATRFTRSSEKHPECCQCFTGEHFRQLAVFTTGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3ZCQ3-1", "uniprot_id": "F174B_HUMAN", "id": "Q3ZCQ3-1", "name": "Membrane protein FAM174B", "aln": "MRAVPLPAPL-LPLLLLALLAAPAARASRAESVSAPWPEPERESRPPPGPGPGNTTRFGSGAAGGSGSSSSNSSGDALVTRISILLRDLPTLKAAVIVAFAFTTLLIACLLLRVFRSGKRLKKTRKYDIITTPAERVEMAPLNEEDDEDEDSTVFDIKYR------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVN1-1", "uniprot_id": "F174B_DANRE", "id": "Q1LVN1-1", "name": "Membrane protein FAM174B", "aln": "-------------MWLYTFAVALIVIAQEINGEPHTRPSSATPL---------NATLPPQ--EEGSAQ---NTTDAAVGSRLSTILRDLPTIKNISIFICVLTTLLITCLVIKICRSARKIRKTRKYDIITTPAERVEMAPLNEENDEEDDSTLFDVKYR------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: .* . * . :. . . *.. *:* . *... *:: *: :*:* :******:* *. .:::***:**:::: * .::::**********************::**:::*::**::* ", "identical_positions": 53, "similar_positions": 48, "identity": "22.84%" }, { "cls_id": "homologset.agr.HGNC:3434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AH26-1", "uniprot_id": "A0A8I6AH26_RAT", "id": "A0A8I6AH26-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "MTGRLSQWHREEGGALGHAPSLNIQEAGEWTPGQAAMKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQD--ASLPHCRFYEEFDTHGRQVPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTITNPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQ-------------SEETLQRIEQIAQQL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08811-1", "uniprot_id": "ERCC2_MOUSE", "id": "O08811-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQD--ASLPHCRFYEEFDIHGRQMPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASVARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPVLHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQ-------------SEETLQRIEQIAQQL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18074-1", "uniprot_id": "ERCC2_HUMAN", "id": "P18074-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHD--TSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLE-------------SEETLKRIEQIAQQL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVP9-1", "uniprot_id": "Q7KVP9_DROME", "id": "Q7KVP9-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLSVDGLLVYFPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEHPETVRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMD--TETPICQYFEGFSLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASVQRDT-DMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITHFATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALMNYVKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHLVDSFCNLSTEEAVQLARRWLRRMAQPFTREDQLGISLLTLAQLENM-----------EQEKLERQAQGKQGVGGEVQEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06839-1", "uniprot_id": "RAD3_YEAST", "id": "P06839-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD/RAD3", "aln": "------------------------------------MKFYIDDLPVLFPYPKIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQMHYP-EHRKIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEVSKERKGTVVDEKCRRMTNGQAKRKLEEDPEANVELCEYHENLYNIEVEDYLPKGVFSFEKLLKYCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHNIDNVCIESLSLDLTTDALRRATRGANALDERISEVRKVDSQKLQDEYEKLVQGLHSADILTDQEEPFVETPVLPQDLLTEAIPGNIRRAEHFVSFLKRLIEYLKTRMKVLHVISETPKSFLQHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEGFLLIIEPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMYPRMLNFKTVLQKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPDGMVVFFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSLALETYRKACSNGRGAILLSVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRIRENDFLSFDAMRHAAQCLGRVLRGKDDYGVMVLADRRFSR--KRSQLPKWIAQGLSDADLNLSTDMAISNTKQFLRTMAQPTDPKDQEGVSVWSYEDLIKHQNSRKDQGGFIENENKEGEQDEDEDEDIEMQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :*.* * *** *****: ** ::*::**. *: :**********.:**:* :** :* *:******:.****.: **.:*: : :. * ** *:****:*:****: * *. ** ** :* . : : : * :. *.:.* : : ** *::.::.* . : ****:.* * .::::************: **:*:::.: *:************:*:*:.:. :: *. : * : : ::: * ::*.:**.::*:**:.*. : : : .****:::* *.:**.** *:**:.**:*::**:* *::* **:.*:* .**. : . *:*******:*** *::***:::: :: .*. :: ****:*** :** :****:: ...::.**:::*:*:*:*:*: ***.**.:*:*****:**:*:**::*:*..* :::****: .: ***: :*.***:***:** *:* :::****.:*:*.: .***:* **.** *:** *: * **:: : : **:::** * *** ** .* :**. ****:**:*********:** *:***:*:*:*:*: **:********:::*::::*******:**********:**.:*** ***:*::**:**:* **.:**:** : * *: **:.: .:. :: :** **** :** *:*: : :* .:*. : : : ", "identical_positions": 345, "similar_positions": 250, "identity": "42.12%" }, { "cls_id": "homologset.agr.HGNC:34342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB93-1", "uniprot_id": "D3ZB93_RAT", "id": "D3ZB93-1", "name": "", "aln": "MGEQWLPWNRPRQVLQPMPLGMTSKPWFKDRLPSKCFAKHKQEQLKFPTSLDGRRWVFVKEGLDDFRKGCPPSKGMIIRGPKEGFLPTITHQVHRGSKKSKQKR-CQDVNLFSSLSLAQQARKSFVEKTEANLTQHPLAFWP-LEEGVPSDIDFLENVLEALDTDQKLEEKLNQCEVSRKSIQSVHLPSVAEDYPEKQEEREPPKFPGARKHGVLHDKKPRKKNPAKESLYYRHIPKGVYDFCAWVDSFGDLGIDEHFMMKQFDIGYECKPVYTDSAIKKISLLPTDLRLCRRLSKVKEIRFSIQEANFERKLRKPIDPYKPTRDKIRYGAWYLKPYLWKKLVNDEPLLDPEELFELEGGRPGKPDIIEDLYGTIAFKDFIISKGYNMPTILEKLFMRKGWNYDTVNTPIPRVLKAHELIMQQKDEDYDDEND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NHR8-1", "uniprot_id": "FA47D_HUMAN", "id": "A6NHR8-1", "name": "Putative protein FAM47D", "aln": "MGDQR-PRDRPR------SPGMDCKPWYCDKPPSKYIAKRKHRRLRFPP-MDTQNWVFVKESMDSFHYGCPSPEDMLICRLNEFLLPKISHRGPQADPKSRQKKLLKKVALFSKLLPAQPAWKAFVEEAQL-MAKHPLAMYPNLGEDMPP--DLLLQMLKLLDPERKLEKAWAYCEGREKTIKEPTKPEPPK-APVSHHFLEPPKIRASCLKELLQEDTPSTTECVSDSLQHRYTSRKMHDF-KWAR---DMGVDEESIRNLFDFTPKWRATYEDQQIKKIKEWVSELQYRIKLDEMDEVE-SSQEKDWDRKLQMAPNSYTAQCVKMRYGVWYLKPKLGKKLRSDQPLIDPKLLLE----KPDEPDILDDLYGPIAFKDFILSKGYEMPGIIERLCARKGWTYDSVKTPVQRAMRLYK---------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* * :*** . ** .***: *: *** :**:*:.:*:**. :* :.******.:*.*: ***..:.*:* :* :**.*:*: :.. **:**: :.* ***.* ** * *:***::: :::****::* * *.:*. *:* ::*: **.::***: ** .*:*:. *. .: * .:. ****: .: : :*::..* ..: ..:** :*: .: ::** *. *:*:**. : : **: : :..* *. ****. ::*: :*.::.*:. * ** :::***: . :.*.. *:***.***** * *** .*:**:**: *:* :*.:***::****.*******:****:** *:*:* ****.**:*:**: *.:: :: ", "identical_positions": 167, "similar_positions": 147, "identity": "38.57%" }, { "cls_id": "homologset.agr.HGNC:34343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3YWC7-1", "uniprot_id": "D3YWC7_MOUSE", "id": "D3YWC7-1", "name": "", "aln": "MAECGQRLQPTTLAPRLLRERQNCG--WYLGNLPPKRFIRRNRLTCQGFLNSRHWVFVKE--DNFRKDCPP-----HQSPKDAFLPLIHRGAPSATPEKRQSTLLKGATLLSKLS---KAGKAFLEDVEAEAAQHPLTLYPQLTEALPAELLLQVLEVLDPERKLEDVWAYCQDTRKPMKEPTELVGKRSSQE--RPPKKTLISRSGQWLCEEKSSKVDSLYKDRLLHDDVHRGVTDFCHWAEDLGSSAIEEEFVLQQFDIGYQTRRSCDALLRLRLNQDKLFINRPPSLREHCG------HWSEPRSSGRANPQKPKRVKMRYGAWYLNTSLWKRQRADEPLVDPMVSHKAQDSTFKEQLQEQGELLAGLRGTAAFKDFILSRGYRMPRFLEKIYAEE-KNKSENIKAPKKLTQTEKNPGSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A2J7-1", "uniprot_id": "A0A8I6A2J7_RAT", "id": "A0A8I6A2J7-1", "name": "", "aln": "MAERGQRLQPKTLAPKLMRERRNCG--WYLENLPSKRLPKSSRLT----LNSRHWVFVKEGLDDFRKDCPP-----HQGPKDAFLPLIHHGAPNATPKGRQSRLPTG-TTLSKLS---KAGKTFLEEVEAKATQHPLALYPQIKEALPAELLLKVLEVLDPERKLEDAWACCRDTRELMKEPTKLVEERSSQV--CPPKKMLMSRSGQWLCEEKPSKVDSLYKDSLLHDDIRRGVSNFCHWAADLGSSTIEEEFILQQFDIDYQTRCSCDELHRLRLTQDKPCINGPPPHRERCG------HGIKPRSSGRANPQQPKRVRMRYGAWYLNTKLWKRQRADEPLVDPRVSPKAQDSNFEKQLQEQEELLADLCGTAAFKDFVLSRGYRMPRFLEKIYAEEEKSKSENIRTPKKLTETERNPGRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZV65-3", "uniprot_id": "FA47E_HUMAN", "id": "Q6ZV65-3", "name": "Protein FAM47E", "aln": "MADRRRRLRPGTLAP--VREGVNCRSRCFTKHKNGLKFPTS--------LHSRQLVFPRKGLDDFRKGCPPCTGLVTQVPVEGFLPQIYHRAPQLAPKKRQIKLLKEADVLSKLSPAQQARKAFLEDVEAHLTPHPLALYLNLEEAMPIELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVYLGPSKKTSVSNAGQWLYEEKPHKMD------LLHENGPR------PGLHENGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFFQKLGYERKLQKPQNPYKPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADLHGTVAFKDFILSRGYRTPRFLENMYIGK-ECKRACNKTPIKRTQA-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: :**:* **** :** ** : : :: *:**: ** :: *:***.*** * * :.*** *:: **. :*: ** * . ***** :* *:***:***. : ***:** :: **:* *** :*******:*****.** *:***: *****:*: ::*:* *.** :*.:**** ***. *:* ***:: * : * * *:***:*:****.*:*: * * * ::*.* :: . : : : . ** :** *:*********..***:**.******* ** ***:..*:::**** ****.* **.*****:****** *****::* : : * ::* * *:: ", "identical_positions": 186, "similar_positions": 89, "identity": "43.97%" }, { "cls_id": "homologset.agr.HGNC:34345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9P2-1", "uniprot_id": "D4A9P2_RAT", "id": "D4A9P2-1", "name": "", "aln": "MTSIKEQAAISRLLSFLQEWDNAGKSLRTQILTTFIETNQGKTGPELELEFSQGASLFLIRVTTWLRIIYMTGLDLEMILRSIGIFLSAVSSNRYLIEFLEIGGVLTLLEILGLEKIKEEDKKESIKLLQIIANTGRKYKELICESYGVRAIAEFLAKSKSEETQEEVQVLLDTLVHGNPKYQNQVYKGLIALLPCGSPKAQQLALQTLKTAQSIVGATHPSIVDCVLMVLSTVHLEVQYEAIELIKDLIHYDVRLPLLKGLIAMLIPPVKETSKLQARIFSDSSILQITTQLPVFLQQAAAAKTIGILARSDLNLAEEMLHLRVIHSLMSAMGNTDHSNSQRLASLTLEYFVQMFPLVEEHVRNSMGEELYQLFLSDAEILYTKIDSIQADILAANKVNVTRDSCDHINNSCISFSTSSDASNQVGGISDFEKLHSESRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q963-1", "uniprot_id": "E9Q963_MOUSE", "id": "E9Q963-1", "name": "", "aln": "MTSVKEQAAISRLLSFLQEWDNAGKGLRNQILTTFIKTNEGKTGPELELEFSQGASLFLIRVTTWLRIIYMTGLELEKILRSIGIFLSAVSSNRYLLEFLEIGGVLTLLEILGVEKINEEDKKESIKLLQIIANTGRKYKELICESYGVRAIAEFLAKSKSEETQEEVQVLLETLVHGNPKYQNQVYKGLIALLPCESPKAQRLALQTLKTAQSIVGATHPSIVDRVLTVLSTVHLEVQYEAIELIKDLIHYDVRLPLLKGLVALLMPPVKETSKLQAKIFSDSSILQTTTQLPVFLQQAAAAKTIGILARNDLNLAVELLNLRVVHGLMSAMGNTDHSNSQRLASLTLEYFVQMFPLVEEQVRKSMGDELYQLFLNDAEILYTKIDSIQADILAANKVNATTDSCECIDNSSISFSTGSNDMNQRGYTNDFEKLHSKSKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIY5-1", "uniprot_id": "ARMD1_HUMAN", "id": "Q6PIY5-1", "name": "Armadillo-like helical domain containing protein 1", "aln": "MTSIKEQAAISRLLSFLQEWDNAGKVARSHILDKFIETNQGKTAPELEQEFSQGASLFLVRLTTSLRITYMTDSCLEKLLRSIGIFLSAVSSNRYLIEFLEVGGVLTLLEILGLEKIKEEAKKESVKLLQVIANSGRTYKELICESYGVRSIAEFLAKSKSEETQEEVQVLLDSLVHGNPKYQNQVYKGLIALLPCESPKAQQLSLQTLRTAQPIIGTTHPSIVDCVLKVLGTMHLEVQYEAIELIKDLVGYDVRQALLKGLVALLIPSVKEISKLQAKILSDPSVLQLTPSLPMFLQQAAAAKAIGVLARNDMSIAEELLYLRVVRGLMAAMGNTDHSNSQRLASLTLECFVQMFPLVAEHVRKCMGEELYQLFLSNAEDLYMKIDSIQADILAANTVNVTKALCLHGSSYSMNTLYGSRDSAQMAYLTHFEEDVE-SKE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:********************* *.:** .**:**:***.**** **********:*:** *** ***. ** :*****************:****:***********:***:** ****:****:***:**.************:*********************::********************** *****:*:****:***.*:*:******* ** **.*:***************: **** .*****:*:*:*.*** *****:*:**.*:** *..**:*********:**:***.*:.:* *:* ***::.**:******************* ******** *:**:.**:*******.:** ** *************.**.* * .. .:. .* * . ..**: . *:*", "identical_positions": 324, "similar_positions": 74, "identity": "73.47%" }, { "cls_id": "homologset.agr.HGNC:34346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVL4-1", "uniprot_id": "D3ZVL4_RAT", "id": "D3ZVL4-1", "name": "Cilia-and flagella-associated protein 96", "aln": "MPIEGGKTDMERIGLFSEMEYITVGDRYVSPFNRPFNEAASKNRQMLPGGTKEMSNLQAGYFDPQFARIFEGEGYLNLNQVRRQYMMAEAKKNLGKAFIPSSGEKKPSGLGSYYGTIGGPVPFFSAQIKPRDKYQPPGKNLYTNPGKKGTGYGYANVTIGRQLSHSSDLYDAAKQNFKKESEEHHRLMKGSPFKLHLHPKDYFDTNPYFLEHPLPPLRREEKKESSVKPFKPSSPGKKAGGMKAGTFEPYPSHSADPYVVKVGKVMPSKGE-KVFHPPNGPKSRPIESIMALNVRRALNVKNY-KNASSSTLEKQLVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1D9-1", "uniprot_id": "CFA96_MOUSE", "id": "Q3U1D9-1", "name": "Cilia-and flagella-associated protein 96", "aln": "MPIEGGKTDMERIGLFSEMEYITVGDKYVSPFNRPFNEAASKNRQILPGGTKEMSSLQAGYFDSQFARIFEGEGYVNLNQVRRRYMLAESKKNLGKAFIPSSGEKKPSGLGSYYGTIGGPVPFFSAQIKPKDKYQPPGKNLYTNPGKKGTGYGYANVTIGKQLSHSSDLYDAARQSYKKESEEHHRLIKGSPFKLHLHPKDYFDTNPYFLEHHLPPLRREEKKEVSFKPFKPSSPGKKAGGMKAGAFDPYPAHSADPYVVKVEKAIPSKGE-RVFHPPNGPKSRPVESIMALNVKRALNVKNY-KNASSTTLGKQLVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A7E2U8-1", "uniprot_id": "CFA96_HUMAN", "id": "A7E2U8-1", "name": "Cilia-and flagella-associated protein 96", "aln": "MPAEGGKTDMERIGLFSEMEYITVGDKYVSQFNRPFNEAASKNKQMLPGGSKEMSDLQAGYFDPHFVRIFEGEGYINLNQVRRRDMVEAAKKNLGKAFLPSNGEKKPCGLGSYYGTIGGPVPFFSAQSKPREKYKAPGKNLYTNPGKKGTGYGYANITIGKQFSHSADFYDAAKLKYKKANEEHHRLLKGAPFKLNLHPRDYFDANPYFSEESLPPIKKEEKKKTISNTFKPSSPGKKPGGMKAGTFDPYPSHSADPYVAKLAN-ISGKDD-KIFHPPSGPKSRPVESIMTLNVRRALNSKNY-KTSSVPSY------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P4C5-1", "uniprot_id": "CFA96_DANRE", "id": "Q0P4C5-1", "name": "Cilia-and flagella-associated protein 96", "aln": "MPPDG-KSDMERIGVFKEMGYISIGDKYTSFIYRPFNDSAYKNKQMLLGGTKSKCGLQTGYFDTQFKRIFEREAFTDPVRIDRQYRILQAKKNIGKAFLPSNGEKTTCGMGTYYGTFGGPIQAMSALQIPRKQNKSAGKNFYTNPPKEGSGYGCPDITLSKMVSYSSDPYDRAKEMLKREITAHKSMLKGGAFRLNLHPNEYFDGNPYKFDKPLPPPKKIEEKKHFAVPFKPSSPSKKAGGMKAGAFDSYPTYSAEPYGTKKTKSVVANNEVKIFHPSPGPKSTPIKSIISLNVNKAVNSTNYNRIPSVMSF------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :* *:******:*.** **::**:*.* : ****::* **:*:* **:*. ..**:****.:* **** *.: : :: *: : :***:****:**.***...*:*:****:***: :** *:.: :..***:**** *:*:*** .::*:.: .*:*:* ** *: *: *: ::**..*:*:***.:*** *** :. *** :: *:*: .******.**.******:*:.**::**:** .* : : .:.: ::***. **** *::**::***.:*:* .** : .* : ", "identical_positions": 147, "similar_positions": 104, "identity": "46.23%" }, { "cls_id": "homologset.agr.HGNC:34347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8P9-1", "uniprot_id": "D3Z8P9_RAT", "id": "D3Z8P9-1", "name": "", "aln": "MTMAGRLGQKMNQDEVHQNQIMRELFLKEFRTQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLVHHAAQGPKKKYSETQTEAQEIGWDPHPLINPDRQDRRLNHFRVYHDITLYKAKLWSLGEDDHQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NC57-1", "uniprot_id": "CF144_MOUSE", "id": "Q5NC57-1", "name": "Cilia- and flagella-associated protein 144", "aln": "--MAGRVGQMKNQDEVHQNQILRELFLKELRAQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLIHHAAQGPKKKYSETQTEAQEIGWDPNPLINPDRQDHRLNHFRVYHDITLYKAKLWSLGEDDHQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NL82-1", "uniprot_id": "CF144_HUMAN", "id": "A6NL82-1", "name": "Cilia- and flagella-associated protein 144", "aln": "--MAGHPKEKVIPDEVHQNQILRELYLKELRTQKLYTQYHVNPLRKIHTVTRKPMSWHDNLEEPADARFLNLIHHAAQGPRKKYPETQTENQEVGWDLEPLINPERHDRRLNHFRVCSDITLYKAKTWGLG-DDHHK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBI9-1", "uniprot_id": "E7FBI9_DANRE", "id": "E7FBI9-1", "name": "", "aln": "--MA-KLKEKEPLDIVHQNAIHVETIMKELRHQKLYTEFNINPFKKLHVLTDKPMSSIAHKKEEGDPAFLQAVHNAHLEPTKKYTHPQTESQEIGWLSSPLLVTDRSDRRLNFPRQNSEITKYMDAAWRLKEQTQNMR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : : * **** * * :**:* *****::::**::*:*.:* **** : :* *. **: :*:* * ***...*** **:** **: .:* *:***. * :** * * * : :: ", "identical_positions": 56, "similar_positions": 32, "identity": "40.58%" }, { "cls_id": "homologset.agr.HGNC:34348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZI1-1", "uniprot_id": "TRNP1_MOUSE", "id": "Q80ZI1-1", "name": "TMF-regulated nuclear protein 1", "aln": "MPGCRISACGPGAQEGTAEPGSPPPPPREPLPSLQPPSPSPTSTPTPT--KSPPLPEAAET---PVEGQELQRWRQGASGGSGGAGPAGI--AGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGARRGRRGRPPALLASALGLGSCVPWGAGRLRRGQGPEPDSPFRRSPPRGPASPQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K0Y1-1", "uniprot_id": "A0A0G2K0Y1_RAT", "id": "A0A0G2K0Y1-1", "name": "", "aln": "MPGCRISACGPGAQEGTAEPGSPPPPPREPLPSLQPPSSSPTSTPTST--QSPQLPEAAET---PVEGQELQRWRQGASGGSGGASPAGIGGAGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGARRGRRGRPPALLASALGLGSCVPWGAGRLRRGQGPEPDSPFRRSPPRGPASPQR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NT89-1", "uniprot_id": "TRNP1_HUMAN", "id": "Q6NT89-1", "name": "TMF-regulated nuclear protein 1", "aln": "MPGCRISACGPGAQEGTAEQRSPPPP-WDPMPSSQPPPPTPTLTPTPTPGQSPPLPDAAGASAGAAEDQELQRWRQGASGIAGLAGPGGG--SGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGPRRGRRGRPPALLASALGLGGCVPWGAGRLRRGHGPEPDSPFRRSPPRGPASPQR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************* ***** :*:** ***..:** ***.* :** **:** : ..*.************ :* *.*.* :**********************************************************************************.*******************.************:*********************", "identical_positions": 193, "similar_positions": 19, "identity": "83.91%" }, { "cls_id": "homologset.agr.HGNC:34349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PVP9-1", "uniprot_id": "E9PVP9_MOUSE", "id": "E9PVP9-1", "name": "", "aln": "------------------------------MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVQMET----SLGLPPSGQTYCQLQSPELCN----TCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIK----------EGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQ-----------------DQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWD---LVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGP-ENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGS--VTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQH-HSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3V0A6-1", "uniprot_id": "CB078_MOUSE", "id": "Q3V0A6-1", "name": "Uncharacterized protein C2orf78 homolog", "aln": "------------------------------MSENSQSSPFFGTESTLHPSLPLLSNSIQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMGNAYLNPHAGTTMLTVLTEQGQISTSTPSYPGALKWDCTGSTHGREDALQEFNMKLIDQDTTLSSLAVTNQSDKILDPNVIVPFHPTLSSSFVQITPSQMPNQ-GYSLAPSYQEGS-QVYYYEHNNLGPLIAGEFGQCLKAHGSVSYPGSQTSVLQPEMVMVLKEIQPRNIQMPLFTSAFSYSTSAQSMPDNGLPVVQMET----SLGLPPSGQTHCQLQSPELCN----TCVQVSQIRPPAVNGDKALTAPIHSPSEFLALPPAPSLEQPENKTMPEIK----------EGTKENQDRPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENENGSSFNFKDITRLEADIQLPQLLNTLTDIDQ-----------------DQSCETWTVTSGPSDQVRKNKHKSFELLEGAPQAKFQHWD---LVEGEGAGGVAGASERAIDNMAKQPEGKAPKGPPSKNRKARKQEQERPSGP-QNKSKKTEELKQSRNTAKAEENLSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKTEKKTGISSFRGLRTFTINKDPGPGSGTVTTTVLNMPCEGQFPPKSPGKVQRAESSIDKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRTTTVQP----HSHSAQPTTLRPAQPPPVSSSLIASAKPAPPISSSSTGPNVTNPNQSSAVPHLVTSRPVPYRASSHTSFQRELVSAAR-----------------------------NKVPSPPKPQTKYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRQAQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "W4VSN8-1", "uniprot_id": "W4VSN8_MOUSE", "id": "W4VSN8-1", "name": "", "aln": "------------------------------MSENLQSSPFFGTESTLHPSLPLLSNSIQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMGNAYLNPHAGTTMLTVLTEQGQISTSAPSYPGALKWDCTGSTHRREDALQDFNMTLIDQDTTLSSLAVTNQCDKILDPNVIVPFYPTLPASFVQVTPPQMLSQ-EYSLAPSYQEGS-QVYYYEHNNLGPLITGEFGQCLQPHGSVSYPGSQTSVLQPEKVMVLQEIQPRNIQIPLFTSAFSYSTSAQSMPDNGLPVVQMEM----SLGLPPSGQTHCQLQSPELCN----TSVQVSQIRPPAVNGDRALTAPIHSPSQFLALCPAPSLEQSENKTMPEIK----------EGTKENQDTPILTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCIYMGPKELVGLEKEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQ-----------------DQSCENWRVTSGPSDQVRKNKHKSFELLEGDPQAKIQHWD---LVEGEGAVGVAGASDRAIDNMAKHPEGKDPKVPPSKNRRARKQRQERPSVP-ENTSKKTEELKQSRNRVKAEEKPTIPKTKRKRNPPELSQNSFKKPRSNLAMHMLESVQVFHPLGKKIEKKTGISSFGGLRTSTNNKDPGPSS--VTTTVLNMPGEGQGPPKSPGKLQRAESSVDKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTTVYPVQP-HSHSAQPTTLRPAQPPPVSSSLIASAKPAPPISSSATGPNVTNPNQSSAVNQLATSRPVPYRASSHTSFQRELVSAAR-----------------------------NKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRAQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LTK0-1", "uniprot_id": "F1LTK0_RAT", "id": "F1LTK0-1", "name": "", "aln": "------------------------------MSENFQSSPFFGTERARQLSLPVLSNSTQSAGRVCNISRVSTPDMNSPWLLPSASSTSLQPLMGNAYLNPHAGTTMLTVLTEQGQISTSAPSYPGALKWDFPGSRDGREEALQGVNVTIIDQDTTLSSLAITNQCDKILDPSAIVPFYPTLSASFVQVTPPQMPNQ-GYSLAPSYQDGSSQVYYYEHNSLGPLIAGEFGQCLQAHGSMPYPGSQTSAIQPEMVMVLKEIQPRNVQIPLFTSAFSYSTSAQS---NSLPVVQMET----SLGLPPSGQTHCQLQSPELYS----TCAQVSQIRPSAVNGDRALTAPIHSPSEFLALPPAPSLEQTENKNVNEINDEFLKTLDAYEGTKENQDTSIVTLAHPDLQQPLQCADTEGLRPKSASDIAHLEGISMGPKKLGGLENEIRSSFDFKDISTLEADIQLPQLLNTLTDIDQ-----------------DQACENWKVISGPSDQVRKNKHKSSEPLEGAPQAKIQHQD---LVEGEASVCVAGTSNKAIENMAKHLEGKAPKVAANKNKRGRKQGQEKPSGP-ENNSKKTDELKQSRKRVKAEEKPTVPKTKRKRNPPELSQTSFKKPRTHLGMHMLESVQVFHPLGKKSEKKPGISSLGSLRTFTSNKDPGPSP--VTTAVLNMSCEGQGPPKSPRKTQIAESSASKECPSQSQYELPPAGKVKLVPLPFPTLDKPQARPISRKPLSLASHRPTTVHPVQP-HSHSAQLTTHRPSQLAPVSTSSMASTKPASPISSSATGPSGTNLIQSSAVPQVATSRPVPHRASSHTSFQRELVSAAK-----------------------------NKVPSPPKPQTQYLLQDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRAQQERENAVKNTATGKLQLFLQREKDMEISQYYGYAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LZ55-1", "uniprot_id": "F1LZ55_RAT", "id": "F1LZ55-1", "name": "", "aln": "------------------------------MSENVQSFPFFGTESAPQP-----LNNFTPSGRVCNISRVSTPAVSLAWVLPPTTSTSLQLIAGRAYLNPQASTTMLVELTDQRQNSTSALFYPGALKWDLTESKG---------NTTITDQDTTLSSLSVTAQWDESLVPNTTLPFSPTLFTNFVQVTPPQVANR-EYSLALPYQEGS-QTYYYNYNSLGPLMPGELGQCLQPYGSVSYPASEECAPQPEVGVVEKEIQPRNLQIPLSTSDLSRSTSVQNTPDTSLLVVDTET----FPGLPPSGQTLCLLESPELCT----ISTEVFQMRTPPVHGHGSLAGPICCPSEILALPPAPGPEQRENGNMHEVKAELSKPPDAYVGTKENQDPSHLPLVD--------YTDTRRLRQKSASDSASLGGIGMGLEERGELENESGSSINFEDIATLEEDNDFPQLFKTLNDIDQ-----------------DPLLQNWGVMSSPSEKVRKNDLNASDQLDGAPQAKIQYQD---LVEGERAMGSTGDKDGTIDKITKHLEGKAPKVAPSRHSKGRKLGQEGPSGP-ENNSKKTDELKQSRKRVKAEEKPTVPKTKRKRNPPELSQTSFKKPRTHLGMHMLESVQIFHPLGKKNEKKTGISSFRGLQTFTSNK-PGPAT----PTLLDMPHGGQGFDRSPGKVPRSETSAHKECPSPSKNKMPTAGKVRLVPLPFPTLDQPQARPVSRKPLPLASHRPTAAYPVQP-HSHSAH-----PCQLAPVNTSLMSSAKPALPISSSATRPNVGKTVQSRSVPPLAYMRPVPYRVPSHASFQRELVSAAR-----------------------------NKAPSPPKPQTQYQLQDFSCQSIPWREVDILGPVISQPITKEQRPEREAMKRRAQQERENAAKYSCSGKLQLFLHREKDMEISQYYGYAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0U1RPT6-1", "uniprot_id": "A0A0U1RPT6_MOUSE", "id": "A0A0U1RPT6-1", "name": "", "aln": "------------------------------MSENFQSTPNFGTKSTLQLSLPVLKNST-PSGMVCNYTSVSFPPVSSAWLLPSASSTSLQPLMGSDYLNPNSSMTMLTMLSDQSQVSNSTLSCP--------------------------------------------------------------------------------------------------------------------------------------------------------------------VVEMDT----SLGLSPSSQTLCLLQSPEFYI----TCTPVSQRKTPSVDGDGPLTTSIPSHSEFLALPPAPSAEQTEIKNMHEMEVEHLMPRDAYKGTKENQDPSFLPLSHPDLQQPLHCIDTGNLRQTSASDNDSLGGIHLGLEEKGTLDSLKVSTIDFPDITTLVADIHLPQLFKFLTGLDQYQDSTVTESKDSTVVWRDQAQENSRVISGSSDQVKKKDHDTSELIDGAPHAKIPNWD---LVVGEGSMASVGVSGRAIDNMAKDLEGKAPKVSPIMPSRARGQGQDKTKWTTENNSKKIEELKKSRNRAKAEKKPTIPKTKIKRDLPELSHSSFKKPRTHLGMHMLESVQVFHPLGKKSEKKPATTSSQHLGTSSSNKYPGPGP--ATTVLQDMAHECQGPDETPGKVQRAESSALKECPSQSQYEVPPAGKVRLVPLPFPTQDQPQTRPVSRKPLNLASHRPTTAYSERC-HFHSAQLTTLKPSQPPSISKSLMASAKPALPISSSAMRSNVTNIIHISTVPQSGTLRPTSYREPSQTSLQRELLSAAK-----------------------------NNVPAPLEPQTQYLLQDFSRQPIPWRKVDILGPVVSQPITKEQRPEREAMKRRAQQERENAAKYTSPGKLQLFLQREKDMEISRYYGYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NCI8-1", "uniprot_id": "CB078_HUMAN", "id": "A6NCI8-1", "name": "Uncharacterized protein C2orf78", "aln": "MHWLASATQTSASIVSSSLLSAVDVSSSLTMSEYFQNTSLPGTANSRQFSLPVVSNAAFLTGSISNFSRASAPAISSAWLQPSASGTSFQPLMGSAYLYQHSSTTMLSGVTGQSHICTSAASYPGVFEWDSTASTVKKSSSLRDFTVTVIDQNTAVSSMSMTAQYYKTSDTNTMVPLYPSLSASLVQGTLTQIPNQQGHNLSLPCQIGS-QVYYYNQGTLGPQLS-----CLQSYGSVSYTGYRASAHQPEMVMVLKEVQPTNVLPPVSTSGMYYSVSSQPITETSVQVMETSLGMDTSLGLQSPSQTFCLPQTPEFSKSFSSRNTQTLESNPSPELGDISIT-PVQSPTNLLTLSPAPSQEKNENENLDEIKTNLSKPLDVHQILIGNQDPPLLPVEIPDIHPLLACIDPLGQEEQPGSENANLRNKSLSLEDQGIFENGIESSSDLADITTWVEDTYLPPIFSSLQDLDQPESPSAKKAKDTSAIKVNQVQEKSCVIKGHSDQVRKNKHKASEPIQGAPKAKIQPKNPECLLEREVVVGSATVSNSASVNKAKHSSNKPHKAASSRISKTKSHGQEKTKGNRKNSSKKSEESKQSGKKVKVEEKQTIPNMKRKKNQPELSQKTLKKPRSSLGMHMLESVQVFHALGKKIDMKTGFSSSRTLGSSSNTQNRQPFP--ALKPWLDIQHEGKGPEKIQVKAQKLDGSAEKECTSPSHSELPPPGKVKLIPLPFLTLDQPQARHVSRRPNPLASRRPAVAYPARPDSTNSAQSNAVNPSRPAPTNTSLTGPATPAQPISAKATQPSSANPTQP-TVPQSAASRPSAYKTSSCSSLQREPVSTAV-----------------------------TSLRSLPKPQNQFLIQDFSLQPRPWRKPTVPEPVMSTPITEEQRPEREAMKRKAQQERENAAKYTSLGKVQFFIERERDMEIAEYYGYTI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** *. . ** : : * :* :.* : .* * :. .*: *.::.**:* : *:: . ** ...** * ::**: . . : .... *. .:: .: . :::*:* ***. *: * .: *:: *** . :.: *. . . *: * :. :. ::. *: :: **: * :* ::. * .:** : :. * .. ::*:::. .: : ::* *:**: : *: * . . : : :*. ..* * .. : : *: .. :*.*** :* *:* : .*.*:: ::*: * *:: ****:.::****: *.********:**.**** : *.. :* * : : .: * . :: : . * : * *:* * *: ::*..***:*:**** * *:**:* **:* ** :*.:.. . :*.: *.: .. ..* ..:.** ***:.: .. : : :* ** .:: .* :*:*** :*:* .. : :**.:: ::*** *. **:: : **:* ***:***********::*******.* .. **:*:*:.**:****:.****::", "identical_positions": 189, "similar_positions": 223, "identity": "19.67%" }, { "cls_id": "homologset.agr.HGNC:3435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G005-1", "uniprot_id": "ERCC3_RAT", "id": "Q4G005-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDAPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTVE-GSGGASTSQGVDAQAK------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDSLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSIAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRFGTMSSLSGADDTVYMEYHSSR-NKAST-KHVHPLFKRFRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49135-1", "uniprot_id": "ERCC3_MOUSE", "id": "P49135-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDIPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTAAEGSGGPSTSQGVDAQAT------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRCGTMSSLSGADDTVYMEYHSSR-SKASS-KHVHPLFKRFRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19447-1", "uniprot_id": "ERCC3_HUMAN", "id": "P19447-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRADR--DKKKSRKRHYED-EED----DEEDAPGNDPQEA--------------VPSAAGK--QVDESGTKVDEYGAKD-----------------------YR----LQMPLKDDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAE-SSGGPSTSRVTDPQGK------SDIPMDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSSQASRRFGTMSSMSGADDTVYMEYHSSR-SKAPS-KHVHPLFKRFRK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVV1-1", "uniprot_id": "ERCC3_DANRE", "id": "Q7ZVV1-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--RKDKSDR--EKK-SKKRYYED-EEE----DEE-VIGGESQEA--------------VPAAAGK--QVDESSTKLDEYGAKD-----------------------YR----LQMLLKNDHSSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAISEPVCRPTHAHEYKLTAYSLYAAVSVGLQTSDIIEYLQKLSKTSVPDGIVQFIKLCTVSYGKVKLVLKHNRYFVESAFPDVIQRLLQDTVIRDCRLRSAEGEETELITETISSKSAISKSQQ-DNGGPSSSQPADGQRSG-----TQVPEDIFSYYEQMDKEEEEEEET--QTVSFEIRQEMIEELQKRCIQLEYPLLAEYDFRNDTVNPDINMDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSSVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWMKSQEWGLIILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIRFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAYFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLMFSTRDEQQQLLQKVLAASD--------LDAEEEVVMGEVG---GKP-QFSRRAGTMSSMSGADDALYMEYQMPRGSKASVGKNIHPLFKRFRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02870-1", "uniprot_id": "ERCC3_DROME", "id": "Q02870-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MGPPKKSRKDRSGGDKFGKKRRAED-EAFTQLVDDNDSLDATESEG--------------IPGAASKNAETNDEQINTDEYGAKD-----------------------YR----SQMQLRPDHGNRPLWVAP-NGHVFLESFSPVYKHAHDFLIAISEPVCRPEHIHEYKLTAYSLYAAVSVGLQTHDIVEYLKRLSKTSIPEGILEFIRLCTLSYGKVKLVLKHNKYFIESPHPEVLQKLLKDPVIQKCRLIRSEGE--DFIQGTLDGK-AITQFGTKLPPGATDKPTPDPAAAAGADGTTAVPEDITDFYEKIDKEEEDEDEANLKTVSFEVAQEKIEVIQKRCIEIEHPLLAEYDFRNDTNNPDINIDLKPAAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWKQQFKMWSTADDSMICRFTSEAKDK-PMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQEWGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWLELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKMNKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLVNQGYSYKVITHLKGMDTDSDLMYGTQEEQGQLLQLVLSASD--------LDCEDEKLPGEPGYRPSGSGGAVRRVGGLSSMSGGDDAIYYEHRKKN------IGSVHPLFKKFRG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00578-1", "uniprot_id": "RAD25_YEAST", "id": "Q00578-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2", "aln": "MTDVEGYQPKSKGKIFPDMGESFFSSDEDSPATDAEIDENYDDNRETSEGRGERDTGAMVTGLKKPRKKTKSSRHTAADSSMNQMDAKDKALLQDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQAQDFLVTIAEPISRPSHIHEYKITAYSLYAAVSVGLETDDIISVLDRLSKVPVAESIINFIKGATISYGKVKLVIKHNRYFVETTQADILQMLLNDSVIGPLRIDS--------DHQVQPPEDVLQQQLQQTAGKPATNVNPNDVEA------------VFSAVIGGDNEREEEDDDIDAVHSFEIANESVEVVKKRCQEIDYPVLEEYDFRNDHRNPDLDIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKR-RNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQEVLLKNEEAAGIEVGDDADNSVGRGSNG-HKRFKSKAVRGEGSLSGLAGGEDMAYMEYSTNK---NKELKEHHPLIRKMYYKNLKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.: . . *: *:: . .*. * * . . :: .*** :* : *: ** .****::* :*:::**:***: : *:***::*:**:.** * ****:*************:* ** . * :***. :.:.*::**: .*:********:***:**:*: .:::* **:*.** *: . : .: : .: . : : . *::.*:*:: . ***: :* :* ::*** :::*:* ******* ***:::****:: :******** ***********:*********:***:**.**::* :** .*.*** **: ** *.* : . . ***: *: ..: ::****: :* :** ::::.* :: :***:::*****.:** *****:: : :*.********:****** ***************:**.::*:**.**********:.***:**: .: *::*** ***.**::*****::**:*.** ***:***:**:.**:::.**:***.*.* **::*****:.* ::****:***.***:*****. ******* ************:****: * :**:**:***:** ** ** *** ***:***::****:* **: :* :.: *: :*** ** .: *.::. *. * * * :*.::*.:* * *: . ***:::: ", "identical_positions": 367, "similar_positions": 214, "identity": "42.28%" }, { "cls_id": "homologset.agr.HGNC:34350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NN90-1", "uniprot_id": "CB081_HUMAN", "id": "A6NN90-1", "name": "Uncharacterized protein C2orf81", "aln": "------------------------------------------------------------------------------------------------------------------------MAHEGSRQVRDRGVTRSKAEKVRPPTVPVP-----------------------------------------QVDIVPG-----------------------------------------------RLSEAEWMALTALEEGEDVVGDILADLLARVMDS--AFKVYLTQQCIPFTISQAREAMLQITEWRFLARDEGESAVAEDPTWGE----------------DEEPSACTTDSWAQGSVPVLHASTSEGLEN-FQGEDPGGVDRIPLGRSWMGRGSQEQMESWEPSPQLRVTSAPPPTSELFQEAGPGGP----------------------------------------------VEEADGQSRGLSSAGSLSASFQLSVEEAPADDADPSLDPYLVASPQASTG--------------------------------RGHPLGFHLSLEDLYCCMPQ------------------------------------------------------------LDAAGDRLELRS--------------EGVPCIASGVLVSYPSVG------------------------------------------------------------------------------------------------------------------------------------------------------------GATRPSASCQQQRAGHSDVRLSAHHHRMRRKAAVKRLDPARLPCHWVRPLAEVLVPDSQTRPLEAYRGRQRGEKT---KARAEPQALG---PGTRVSPAAFFPLRPGIPFRDLDSGPALLFPTLNLG----------LSSPSLESKLPLPNSRIRFLTTHPVLPDVARSRSPKLWPSVRWPSGWEGKAELLGELWAGRTR--------VPPQGLELADR---EGQDPGR-WPRTTPPVLEATSQVMWKPVLLPEALKLAPGVSMWNRSTQVLLSSGVPEQEDKEGSTFPPVEQHPIQTG-------------APKPR--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DAQ4-1", "uniprot_id": "CB081_MOUSE", "id": "Q9DAQ4-1", "name": "Uncharacterized protein C2orf81 homolog", "aln": "------------------------------------------------------------------------------------------------------------------------MSHEGSRQARDRGVTRSKAEKARPPTQPVP-----------------------------------------QVDIVPG-----------------------------------------------RLNEAEWIAFMSLEEGEDVVGDILADLMTRVMEC--AFKVYLTQQCVPFTISQAREAMLQITEWRFLARDEGESAVAEDPTWGE----------------DEEPLACTTDSWAQGSVPVLHTPAPVCVEEQFHNEEPGNPDQFLLGSSWD-KESQKPTQPSEPSAEPKVTPRPTATLEAFEEAEPGDA----------------------------------------------LEVPHGQEGSHMLAVPSKESLRSTAEGERVYSPQSSLKQPQVVRLQASE---------------------------------KESSFGSHLSLEDLYLCMPQ------------------------------------------------------------PDAAGDRLSLQS--------------KGQ--LHSSPIGSESHLG------------------------------------------------------------------------------------------------------------------------------------------------------------ALTPAEPSAFQEPE--------VLGERPKHKTTTLRMDSSRLPRHWVRPVAEVLIPDLEVHPLEIYRGRPRRSQAGTATSACESQALSSRAPSKPHVSSPRFPLQRCATFRALGPD-----PSLNLA----------QTSPSFGSNVPFLSPGFRFLPRNPIPPDVASTPTPKLWPLAKWPSGWEREAEQLGELWAGRTR--------VPPQGQEPVEV---TPLEEDSGWPLAAPQVLEATSQVLWKPMVISETMKLVPGVSMWNRGTQELLNPAVIRKEAEEGTPQAP-EQQPIQTG-------------VSKPQVIMKQIRNETPKAWLLPTKPVPHSGS------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28023-1", "uniprot_id": "DCTN1_RAT", "id": "P28023-1", "name": "Dynactin subunit 1", "aln": "MAQSKRHMYNRTPSGSRMSTEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKILKREGADAAAKTSKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGPSSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPALTSPGAAPPLPSPSKEEEGLRDQVRDLEEKLETLRLKRSEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEAKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEESTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPSSSPYECLRQSCSILISTMNKLATAMQEGEYDAERPPSKPPPVEPWPAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQTLLRKKEKEFEETMDALQADIDQLEAEKTELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGGTPGQAPGALPGPGPVKDSPLLLQQISAMRLHISQLQHENSILRGAQMKASLAALPPLHVAKFSLPPHEGPGGNLLSGALYRKTSQLLEKLNQLSTYTHVVDITRSSPACKSPSAQLMEQVAQLKSLSDTIEKLKDEVLKETVTQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLGQRHRLVLTQEQLHQLHGRLIS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:: : **:. .** ..* .* * . *:* : * . : : ::* :. : : *** *: :. * :. ::: :::: :*: * : :*.:..** * : * :*: ::.*: .: :: : . . ... ::. * : .: : . . . . .* : ::* . * :. . * . . : . . . : ::. : . : . . .:.*.:: . .: .***::*.: : . : . : :* : . .. . . : : ..: * . :* ..:*:. : . .*. .:. . *. . . . :: * . *. . *.: :. : . *: :.: . .: . . * : * : .::: **.* : * :* .* ... * .*::: : : :* :: .. * .. : . . . . * : * ..: ", "identical_positions": 59, "similar_positions": 200, "identity": "4.61%" }, { "cls_id": "homologset.agr.HGNC:34351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L170-1", "uniprot_id": "CA226_HUMAN", "id": "A1L170-1", "name": "Uncharacterized protein C1orf226", "aln": "----------------------------------------------------------------------------MFENLNTALTPKLQAS-----------------------------RSFPHLSKPVAP-----------------------------------------------GSAPLGSGEPGGPGLWVGSSQ--------------------------------HLKNLGKAMGAKVNDFLRRKEPSSLGSVGVTEINKTAGAQLASGTDAAPEAWLEDERSVLQETFPRLD---------------------PPPPITRKRTPRALKTTQDMLISSQPVLSSLEYGTEPSPGQAQDSAPTAQPDVPADASQPEATMEREE-RGKVLPNGEVSLSVPDLIHKDSQDESK------------LKMTECRRASSPSLIERNGFKLSLSPISLAESWEDGSPPPQARTSSLDNEGPHPDLLSFE---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "J3QNH8-1", "uniprot_id": "J3QNH8_MOUSE", "id": "J3QNH8-1", "name": "", "aln": "----------------------------------------------------------------------------MFENLNTTLTPKLQSS-----------------------------HSFPHLSRPGAP-----------------------------------------------GSIAPGSGEPGGPGLRVGSSQ--------------------------------HLRNLGKAVGAKVNDLLRRKESSSLGSVGVLEINKTAGAQLPGGEDAACGPWLEDERS-VQEVFPLLD---------------------PPPPITRKRTPRALKTTQDMLISSQPVLSNLEYGTESPPGQAQDSPPAAQP-ISADTSRPESTIEMGE-KGEALPNGEVSLLVPDLIHKNTQEEAK------------LKATEGKKSSSPGPIERNGLKLSLSPISLAESWENSSPPPQARTSSLDNEGLHPDLLSFE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54960-1", "uniprot_id": "CAPON_RAT", "id": "O54960-1", "name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "aln": "MPSKTKYNLVDDGHDLRIPLHNEDAFQHGISFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVSTATAEETDIDAVEVPLPGNDILEFSRGVTDLDAIGKDGGSHIDTTVSPHPQEPMLAASPRMLLPSSSSSKPPGLGTGTPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQSTMGSQDSLLEITFRSGALPVLCESTTPKPEDLHSPLLGAGLADFAHPVGSPLGRRDCLVKLECFRFLPAEDNQPMAQGEPLLGGLELIKFRESGIASEYESNTDESEERDSWSQEE--LPRLLNVLQRQELGDSLDDEIAV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.::. *. * : . : *.:::: *. *. .*. .*.** : .:: .* :** *:::: : : ..: :.. : ::.:. . * .:. ..: . :*: : : .. :: *. : * .:*** . ::..:: .**: .. : :. :. * : : * . :. :.*: * . .: * : : :. : . :.: .:*..:*..: .: * * ::* * **.. ", "identical_positions": 35, "similar_positions": 115, "identity": "6.93%" }, { "cls_id": "homologset.agr.HGNC:34352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C3M9-1", "uniprot_id": "CB080_MOUSE", "id": "Q8C3M9-1", "name": "Uncharacterized protein C2orf80 homolog", "aln": "MERRLVKQEVKRLLGEYIGIRLRENEFDPKGRGQLTFLDDMVNQVTLAHYDLAISVASQWLDCSENLTWLQWEKVRAPLHVRPAYPNRKEREAMILSSYAGVLMNSIPIEEVLKIYGANSSASPDSTKVAQALLPRRSLHPFAMLTAPRAAECNRRQSVKLRRGATNKNTTSSSTKKATGQNGDPVGKGTHTPATNISPTPVLSSAQPFHSSTVMWRNLESAQRQMGLEGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0P641-1", "uniprot_id": "CB080_HUMAN", "id": "Q0P641-1", "name": "Uncharacterized protein C2orf80", "aln": "MERRLIKKEMKKLLGDYIGIRLRENEFDPKGRRQLTFLDDMA------HYDLAISVALQWLDPSEDLTWLEWEELKIPLHGRPIYPNRREREAMILSSYAGILMNSIPIEEVFKIYGADSSADSGTIKVPRVSSLCLSLHPFAMLTAPKAAAYARKQSVKSRKVTTNKNATSISAKEAN--------------ATEWKSSQRFSDTQPKHKVT------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*:*:*:***:**************** ********. ********* **** **:****:**::: *** ** ****:************:**********:*****:***...: **.:. ***********:** *:**** *: :****:** *:*:*. **: ..: :*.:** *. * ", "identical_positions": 132, "similar_positions": 38, "identity": "57.14%" }, { "cls_id": "homologset.agr.HGNC:34353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJH9-1", "uniprot_id": "A0A8I6AJH9_RAT", "id": "A0A8I6AJH9-1", "name": "", "aln": "MEAARD-PGPGLCCKPGGRLDMSHGFVHHIRRNQIARDDYDKKVKQAAKEKARRRHTPAPTRPRKPDLQVYLPRHRDGSTHPVNPDCEESSESSSSGNSELEPPGRQLFCLEYEADSGEVTSVIVYQDDDPGRVSEEVSAHTPLDPAMREALRLRIQEELAKRQSRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q149G0-1", "uniprot_id": "CB068_MOUSE", "id": "Q149G0-1", "name": "UPF0561 protein C2orf68 homolog", "aln": "MEAAQD-HGPGLCCKPGGRLDMSHGFVHHIRRNQLDRDDYDKKVKQAAKEKARRRHTPAPTRPRKPDLQVYLPRHRDGSTHPVNPDCEEASESSSSGSSELEPPGRQLFCLDYEADSGEVTSVIVYQDDDPGRVSEAVSAHTPLDPAMREALRSRIQEELAKRQSRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2NKX9-1", "uniprot_id": "CB068_HUMAN", "id": "Q2NKX9-1", "name": "UPF0561 protein C2orf68", "aln": "MEAGPH-PRPGHCCKPGGRLDMNHGFVHHIRRNQIARDDYDKKVKQAAKEKVRRRHTPAPTRPRKPDLQVYLPRHRDVSAHPRNPDYEESGESSSSGGSELEPSGHQLFCLEYEADSGEVTSVIVYQGDDPGKVSEKVSAHTPLDPPMREALKLRIQEEIAKRQSQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQ58-1", "uniprot_id": "CB068_DANRE", "id": "A3KQ58-1", "name": "UPF0561 protein C2orf68 homolog", "aln": "MEVIRDGEGESVKYKPGGRLDMSHGFLRHIRRNQIARDDYDREVKQ-AKEKQRRRHTNTPRRPRRPDRQVYNPRIRNGSEPGVNAEAEDWNESSS--GTEMENTGTELFWLDYQADNGKITSFIVHKEDKPEVIVQRVAEKNVLDSSMRAALLARVGQEMNKRCDKR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . . ********.***::******: *****::*** **** ***** :* ***:** *** ** *: * *.: *: .**** .:*:* .* :** *:*:**.*::**.**:: *.* : : *: :. **..** ** *: :*: ** .::", "identical_positions": 82, "similar_positions": 43, "identity": "49.1%" }, { "cls_id": "homologset.agr.HGNC:34354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A283-1", "uniprot_id": "D4A283_RAT", "id": "D4A283-1", "name": "", "aln": "MAAESWFAGSLALGPGEAPPSEELGPGPQPYGDPSWS-PAGRPEGSTELEPQRAQS-MMEAPTSTSSREPLAAELGAAPARLPLDSMFSPITDQLRYLLRKADDFQSYLLY-RDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQG-ADAHVDYYFLCYRDTWEDAGQ-----------GPANSCPQIQKLWSIGRWMPLG--PAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILMGQAGPARPPSSAGPAAWAAPAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF25-1", "uniprot_id": "CS067_MOUSE", "id": "Q8CF25-1", "name": "UPF0575 protein C19orf67 homolog", "aln": "---------------------------------------------------------MMEAPASTSSREPLAAELGPAPARLPLDSMFSPITDQLRYLLRKADDFQSYLLYSRDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQG-ADSHVDYYFLCYRDTWEDAGQ-----------GPANSCPQIQKLWSIGRWMPLG--PAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILLGQAGPARPPSAAGPAAWAAPAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJJ6-1", "uniprot_id": "CS067_HUMAN", "id": "A6NJJ6-1", "name": "UPF0575 protein C19orf67", "aln": "MATEQWFEGSLPLDPGETPPPDALEPGTPPCGDPSRSTPPGRPGNPSEPDPEDAEGRLAEARASTSSPKPLVPRPGPAPPRLSLDTLFSPITQQLRYLLKKADDFQSYLLYSRDQVQKEQLAKAMPTFLQMCEPYFLYLEAAARSIPPIYGPLQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEEMNPLSISCFFCGRFSISLSHEVSIFRYCAPTAYTASRFPRYLYKKMRWHLEATPEAPGRG-QDSLVDYYFLCYRDTWEDTGQ-----------SPANSCPQIQKLWSIGRWVPLG--PAEDDLYSWILCPQPLGDYQQLLTIGFEEPTPTLATDLLVQILTGQAGQARPPSAAGPAGWAAQGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNM4-1", "uniprot_id": "CS067_DANRE", "id": "A3KNM4-1", "name": "UPF0575 protein C19orf67 homolog", "aln": "---------------MANTEHDELASLLRETNEAEQSLTDQEAITETVEENTTIASSFGDG-TFLWDEDPLSGYTPSCEDTRIMEDKISRIEKQLQYLLSKADEFQTQLVWSRNCVQDYGFGNIIPMFLETCQPFFSLLESTARNSNPFCPPQSSNIRMQLLQFSQQLCSRLEQLVLLFASFSFCSLEESDPLSVSHFSIGQCQIDN-MKVSIFRYCCPTPFLASSLTG-LYKRMRWNVEREIEGEGDGKTYDSAEFYFLCCEDVIEAADDQNEDRSSEGESTETDSESKVSRIWSIGRWVQTYPDPNTEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGALLSQETHGTFSIIK----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : . .** .. :: :* * .**:*** ***:**: *:: *: **. :.: :* ** *:*:* **::**. *: . .. :* **::**** *******::***.* .*** :***:* * *: .*. .******* *:.: ** :. ***:***::* *. . * .::**** .*. * :.: ::* .::.::******: * :*: .*:**. * *:*:*** :* ***: *** *: * .* . . ", "identical_positions": 110, "similar_positions": 85, "identity": "29.57%" }, { "cls_id": "homologset.agr.HGNC:3436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT95-1", "uniprot_id": "D3ZT95_RAT", "id": "D3ZT95-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MERGLPGERQSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGADRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVKKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDVLNACLKELKYHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLSKKTKTSEKMAGPEEQETKKELVLESNPKWEALTEVL-KEIETENKESEALGGPGQVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDGKAEEVWVNFRKGDGPKRTMKSDKRPKDAQNKERASTKRGALKRKKKRELTLTQVLGTAEEPPEEGAVEEDLHKQTGSS-------PEVCGGEI----------QHESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFFVYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GTAAMDTPTDTRKAGGQE--RNGTQPSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFVQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVQNIAELATLSLERLTGILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZD4-1", "uniprot_id": "XPF_MOUSE", "id": "Q9QZD4-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MEPGLSGERRSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGTDRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLNKKAKTSEKTSSPEVQETKKELVLESNPKWEALTDVL-KEIEAENKESEALGGPGRVLICASDDRTCCQLRDYLSAGAETFLLRLYRKTFEKDGKAEEVWVNVRKGDGPKRTTKSDKRPKAAPNKERASAKRGAPLKRKKQELTLTQVLGSAEEPPEDKALEEDLCRQTSSS-------PEGCGVEI----------KRESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GSAALDAPTDTRKAGGQE--QNGTQSSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFFQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVKNIAELATLSLERLTTILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92889-1", "uniprot_id": "XPF_HUMAN", "id": "Q92889-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MESGQPARRIAMAP--------------------------------LLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----AFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVL-KEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKK-KKRKLTLTQMVGKPEELEEEGDVEEGYRREISSS-------PESCPEEI----------KHEEFDVNLSSDAAFGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVR--GTASADVSTDTRKAGGQE--QNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSN--------------DISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSE------TLPE-SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDFIHTSFAEVVSKGKGKK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U361-1", "uniprot_id": "A0AB32U361_DANRE", "id": "A0AB32U361-1", "name": "DNA repair endonuclease XPF", "aln": "-------------------------------------------------------MASA--------------------------------LLEYETEMFLSVFSTDGLLITAEGLGIDRLLLHFMKVYSEEG--------SLVLLLNTSTPEQEYLTERLRAEGVTHLPQ---------------------TVTSDVQSADRYNVYTKGGVLFVTSRILVVDFLTDRIPAHLVTGILVYRAHNIIESCQEAFILRLYRQKNKTGFIKAFTDKATSFSSGFCKVERVMRNLFVKKLFLWPRFQASVNATLDKH----KPDVVELHVTLTPAMRAIQSSILDIMNACLKELKRYNPTLEAEDLSLENSLGTAFEKTIRHYLDPLWHQLGSRTKSLVQDLKILRTLLLYLTQYDCVTFLNLLESLRTSQK----SFGSNSGWLFLDSSMSMFVNARSRVYRIQESK--KKLKVGETEQKQNLAPPKRELVLEKNPKWEALTEVL-QEIEKENSKSEHE--PGRVLICASDDRTCAQLKEYIQKGPEHLLNRLYSRTIGKE-DPQPDLLKLDKGWQKKDSARS-KGKNSRQKRTKANSKK-------------PAKMEKLSRVSQDDSADKDLN-ENSED-------EGGLIEEE----------EEEEIVLDLSSDDYYGILKEPLTVIHPLKG-CSDPYSLTRVLHEVDPMFVVLYDAELSFVRQLEIYKACR---PGKPLRVYFLIYGGSTEEQRYLTALNKEKQAFEHLIREKASMVVPEEREGREDTNLDLVR--SQEPASAATNTRKAGGLE--EVKEPHRIIVDMREFRSELPSLLHRRGLDIEPVTLEVGDYILTSDICVERKSVSDLIGSLQSGRLYTQCLSMTRFYRRPVLLIEFDPAKPFSLVARSDFRQEISAN--------------DVTSKLTLLTLHFPRLRLLWCPSPYVTAELFQELKHGRTEPDASTAQAVTAESE------TVTESADLYNPGPYDFLLRMPGVNVKNVKSLIKHVSCLADLVTFSQETLSEILGSSSNARMLYEFIHNP-MDVRPIQKNK------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24087-1", "uniprot_id": "XPF_DROME", "id": "Q24087-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------MADSCAENAAKGTENERPKEVEASADTVPQVEEGVEEYLKRKNMV-------------LLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSG--------NLVLVINSSDWEEQYYKSKIEPKYVHEVAS---------------------TAT------ERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIESCQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPW----KIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDCIWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEY----ALS-NSGWTLLDAAEQIFKLSRQRVFNG-----------------------QQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQPKVLILCQDARTCHQLKQYLTQGGPRFLL---QQALQHEVPVGKLSDNYAKESQTRSAPPKNVSSNKELRREEVSGSQPPLAGMDELAQLLSESETEGQHFEESYMLTMTQPVEVGPAAIDIKPDPDVSIFET----------IPELEQFDVTAALAS-VPHQPYICLQTFKTEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILLIEFDQNKPFHLQGKFMLSQQTSMAN------------ADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLGKPEPDPQTAAALGSDEP------TAGE-QLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQESAKLLYDILHVAHLPEKDEVTGSTALLAASKQFGAGSHNRFRMAAAASRRGRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06777-1", "uniprot_id": "RAD1_YEAST", "id": "P06777-1", "name": "DNA repair protein RAD1", "aln": "MSQLFYQGDSDDELQEELTRQTTQASQSSKIKNEDEPDDSNHLNEVENEDSKVLDDDAVLYPLIPNEPDDIETSKPNINDIRPVDIQLTLPLPFQQKVVENSLITEDALIIMGKGLGLLDIVANLLHVLATPTSINGQLKRALVLVLNAKPIDNVRIKEALEELSWFSNTGKDDDDTAVESDDELFERPFNVVTADSLSIEKRRKLYISGGILSITSRILIVDLLSGIVHPNRVTGMLVLNADSLRHNSNESFILEIYRSKNTWGFIKAFSEAPETFVMEFSPLRTKMKELRLKNVLLWPRFRVEVSSCLNATNKTSHNKVIEVKVSLTNSMSQIQFGLMECLKKCIAELSRKNPELALDWWNMENVLDINFIRSIDSVMVPNWHRISYESKQLVKDIRFLRHLLKMLVTSDAVDFFGEIQLSLDANKPSVSRKYSESPWLLVDEAQLVISYAKKRIFYKNEYTLEENPKWEQLIHILHDISHERMTNHLQGPTLVACSDNLTCLELAKVLNASNKKRGVRQVLLNKLKWYRKQREETKKLVKEVQSQDTFPENATLNVSSTFSKEQVTTKRRRTRGASQVAAVEKLRNAGTNVDMEVVFEDHKLSEEIKKGSGDDLDDGQEENAANDSKIFEIQEQENEILIDDGDAEFDNGELEYVGDLPQHITTHFNKDLWAEHCNEYEYVDRQDEILISTFKSLNDNCSLQEMMPSYIIMFEPDISFIRQIEVYKAIVK---DLQPKVYFMYYGESIEEQSHLTAIKREKDAFTKLIRENANLSHHFETNEDLSHYKNLAERKLKLSKLRKSNTRNAGGQQGFHNLTQDVVIVDTREFNASLPGLLYRYGIRVIPCMLTVGDYVITPDICLERKSISDLIGSLQNNRLANQCKKMLKYYAYPTLLIEFDEGQSFSLEPFSERRNYKNKDISTVHPISSKLSQDEIQLKLAKLVLRFPTLKIIWSSSPLQTVNIILELKLGREQPDPSNAVILGTNKVRSDFNSTAKGLKDGDNESKFKRLLNVPGVSKIDYFNLRKKIKSFNKLQKLSWNEINELINDEDLTDRIYYFLRTEKEEQEQESTDENLESPGKTTDDNALHDHHNDVPEAPV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : .:. *.*:: ..**. :: ::: . ***::*:. :: . :. . .: .* .:* .**: ::***:**:*. : . ::*::* .*. : ...:*:* *.::*.**. **:***:. . :* :. :. *::* :::: :****: * : *: : . :*::*.:: : ** ::: :: : *:. * : : .:** : * : : : **::. .:* :* *:::** *: *.* :: :: :* * ::* : :: :: *:: :: *. : :: * . .: : :: . * .: . : : . . : . . . :. : : .: : . : . *.:: * :::::: ::: :**:*::.* :***: :. : *** :**::.:** ** :* ::.: : . * . . :.:*:*** ::** ***.:.** *::: *: : * : :***::*.::*:****:*******:..** .** * :.* * ****** :.* * : . :: ** *.*:** *:::*..** *.::: *** .: :**. .* : ::. * * . . :*.:*** : .* .: : .* * . : :: : :: ::: ", "identical_positions": 159, "similar_positions": 273, "identity": "14.36%" }, { "cls_id": "homologset.agr.HGNC:34360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y6P3-1", "uniprot_id": "A0A8I5Y6P3_RAT", "id": "A0A8I5Y6P3-1", "name": "GDP-D-glucose phosphorylase 1", "aln": "---MAVPHRSQETSYLLPPNPEDWEEQGIPDFVYGQKDLVSKEIQWPKNS----------PSALNSLPLSRFDSALCS-----------AWRQRVEL-GLFRYRLE-DLQTQILPGSVGFVAQLNIERGIQRRRPQNIKSVRQEFDPEQFNFNKIRPGEVLFRMQREPNGPAAPKQED-VLVVINVSPLEWGHVLLVPTPAHGLPQRLLPGVLRVGLEAVLLSQHPGFRVGFNSLGGLASVNHLHLHGYYLAHPLPVEGAPSTPLDPKGYIHLLQALPAP--GFLFYTSGPGPDLEALISRVCQATDYLSDHEIAHNLFVTRGAPPGQASSTS-DLSGIRVILWARKSSFGIKESGAFNVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCLLPQTQADEVQAALVALMAQEEL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TLS3-1", "uniprot_id": "GDPP1_MOUSE", "id": "Q3TLS3-1", "name": "GDP-D-glucose phosphorylase 1", "aln": "---MAVPHHLQETSYLLPPDPEDWEKQGIPDFVYGQEDLVGKEVQWPRDS----------PSAVDTVPLSRFDSALRS-----------AWRQRLEL-GLFRYRLE-DLQTQILPGSVGFVAQLNIERGIQRRRPQNIRSVRQEFDPEQFNFNKIRPGEVLFRMQREPKGPATPKQEDDVLVVINVSPLEWGHVLLVPAPAQGLPQRLLPGVLRVGLEAVLLSLHPGFRVGFNSLGGLASVNHLHLHCYYLAHPLPVEGAPSTPLDPKGCIHLLQALPAP--GFLFYTSGPGPDLEVLISRVCRATDYLSDREIAHNLFVTRGAPPGPTSSTS-DLSGIRVILWARKSSFGIKESGAFNVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCLLPETQAGEVRAALVALMAQEEL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNW5-1", "uniprot_id": "GDPP1_HUMAN", "id": "Q6ZNW5-1", "name": "GDP-D-glucose phosphorylase 1", "aln": "---MALPHDSNETSYLLPPNNEDWGRQTIPDFVYGQKDLMAEGIQWPRNA----------PGIPDALPQSPFDAALCS-----------AWKQRVEL-GLFRYRLR-ELQTQILPGAVGFVAQLNVERGVQRRPPQTIKSVRQAFDPVQFNFNKIRPGEVLFRLHREPDLPGTLLQED-ILVVINVSPLEWGHVLLVPEPARQLPQRLLPGALRAGIEAVLLSLHPGFRVGFNSLGGLASVNHLHLHGYYLAHRLPVEQAPSEPLDPGGHLHLLQDLPAP--GFLFYTRGPGPDLESLISRVCRATDYLTDHEIAHNLFVTRGAPPGKTSPSS-ALTGVRVILWARKSSFGIKDGEAFNVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCRLPPSQAEDVQAALVALMSQEEQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CA1-1", "uniprot_id": "GDPP1_DANRE", "id": "Q08CA1-1", "name": "GDP-D-glucose phosphorylase 1", "aln": "-------------------------MGDCSIFTYTDNDFIGKVCCSGQQN----------RGR------SRFDIALRS-----------GWTEKRNT-GLFRYRLD-ELETRILPGSRGYIAQLNIMRGTERRKPQEILSVRQNFDPKQFNFNKINPKELLFELKRESERKCS--------VIINVSPLEFGHCLLVPEPEKCFPQVLTHLAVQTGIETVLLSADPGFRVGFNSLGGFASVNHLHLHGYYLNHRLKIESSPAKLVLPNLNLYELVDFPS---GFLFYTQGP--NLDLVVKAICSLTDVLVDHNIAHNLFLTRGCPPQMEPDTSSSRNGVRVIVWPRLSCFGAKEESAFNVALCELAGHLPFKNRQDYESATEETVQDIIQKYLLPQEETAQLKEHLMKCL--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSZ5-1", "uniprot_id": "Q9VSZ5_DROME", "id": "Q9VSZ5-1", "name": "GDPGP1-like N-terminal domain-containing protein", "aln": "MFSRHFAAFFRFNRYVAQKYSSFIAAGFSNRFSLKVATLLPLVVLRSADCRQKEDQEVKRPVRRRTMSKVKYETSLEGRAQLYLNAMKVRWDQLHKVPGLFSYQLEKSPQSRKIPGYWGFYAELNSDRNRKRRRPQTIESLNPTFKHMMFNFNKVDAQEVIMTIDDAHGSPEVQ-------MIINKSPITKYHTLICPEVGKNHTQRITRDALQFCITFMRNIDDKDMRMGYNSPGALASVNHLHFHLLHMPQDLYIDHVPLDELAGGYVYRLSRRAPTEGICIVFNENDSDEQVAEKVDQLYMLAMWMCKNNMPHNLFLTQDRRPGKS-------GNIKVFVFARSEYCVNKDLAEFNVGFCELAGYIPLPDADKMENLTELQVLFRIR--TITGNAPKAVYEQITSMVEGQEYYLWDQPLTI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: : :: :* . * : : *** *:* . ::: :** *: *:** *. :** ** * *:. *. *****: . *::: :. ::** **: * *: * : .* : .:: : : . .:*:*:** *.:*******:* :: : * :: * : *: ::* .. :: :. : : : ..::.****:*:. * .::*:::.* . *: ***.:*****::*. :. .. ** . *: :. . : : : ", "identical_positions": 74, "similar_positions": 101, "identity": "17.45%" }, { "cls_id": "homologset.agr.HGNC:34361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXX9-1", "uniprot_id": "CC169_MOUSE", "id": "Q8BXX9-1", "name": "Coiled-coil domain-containing protein 169", "aln": "MGEGHGDTFEGVSTDRLKLELLEEIHMKDVVQLSTLEIRHKIAELEANLN-GDLAGSEWKTRYETQLELNDQLEKQIVSLKEKMEKMRGNPSDRLSSIRVYEKMPVESLNVLLKQLEKEKRSLESQVKEYAFRLEQESKAYHRTNNERRSYIAEMTQVSGSNQVSKRQQMDPLPRMKESPVKTGRHNSMNQKTTNAKKGPVKKVPRSNHLPKLNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABE7-1", "uniprot_id": "D4ABE7_RAT", "id": "D4ABE7-1", "name": "", "aln": "MGEGHGDTFEGVSTDRLKLELLEEIHMKDVVQLSTLEIRHKIAELEANLN-TDLAGSEWKTRYETQLELNDQLEKQIVSLKEKMEKVRGNPSDRLSSIRVYEKMPVESLNLLLKQLEKEKRSLENQVKDYALKLEQESKVFHRTNSERRSYISEMSQVSGLTQVSKRQQMDPLPRMKESPVKTGRHSSVNQKTTNAKKGPVKKVSRSNHLPKLNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNP5-1", "uniprot_id": "CC169_HUMAN", "id": "A6NNP5-1", "name": "Coiled-coil domain-containing protein 169", "aln": "MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLN-TDNEGSEWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QJK3-1", "uniprot_id": "E9QJK3_DANRE", "id": "E9QJK3-1", "name": "", "aln": "MGESDLGNYE---SSRLHAEVEHEREVKEMLQDSVSDLRNTLADLERRLHSVEEEENEWRTRYETQLELNEQLEKQISVVRERLQTLRSDPSDRLASIRSYEEMSEDALRQRLKLLSSEKSGLQAQLMDFRMRIVQEGKAYQKVYEERRAYLAEIAKLSSTLNLSRKQQMAEARRTAAAPDKTAG-KSTKQHSGAAKKGSVNNTPARSRLPRLKH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .:: :.**: :: .* . *: :* * ::*:.:::** .*: : .**:**********::***** ::*:::.::.:.****:*** **.*. ::*. ** *..** *: *: : ::: **.*.::: .***:*::*::: *. ::*::**: * **. .. :*:: **:*.*:: . .:**.*: ", "identical_positions": 71, "similar_positions": 84, "identity": "33.02%" }, { "cls_id": "homologset.agr.HGNC:3437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTV2-1", "uniprot_id": "D3ZTV2_RAT", "id": "D3ZTV2-1", "name": "DNA excision repair protein ERCC-5", "aln": "-------------------MMKSGIASGSDISIWLNQALKGVRDRHGNAIENAHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLAKRRQKKDSASIDSRKTTEKLLKTFLKRQALKTAFRSKRNEVLPSLTQVQRE--DDIYVLPPLQ-EEEKHSSEEEDEKQWQARMDQKQALQEEFFHNPHAIDIESEDFSSLPPEVKHEILTDMKEFTKRRR----TLFEAMPEESNDFSQYQLKGLLKKNYLNQHIENVQKEMNQEHSGQIQRQYEDEGGFLKEVESRRVVAEDTSHYILIKGIQGKKVVDVDLESLPSSSKEHSVSFNLKSSPYEKVKPESEPEATPPSPRTLHAIQVAMLGGSSEEEPESGEGGQSKERSAWATADAGSISPQTCAAIQRALDDDEEERMCA-----SSDNLAVEMLLGNGLKQ-EHADEVVVKGGGVPLDTASLLPSVTEVEECVASASNDKEQTASTHASSTACHPGEVPKETVSPAHVVSEASQISSECEVAGRPVPLPSAFIETPCSYASGVLSERELTLAPP-IRTHSHQRTSID-PEEPELQNGLCPPKNTCNSSHLSSDDETEGGQNPASKAG---------STVHVPSEAVGNVENVSSSNAEEHGDFQKTIQLWEMPEAAAR-ELISAPESLGPVEMESEESESDGSFIEVQSVISNDELQIESSEISKHLSEKDAEEPKETLEEGSPRNTECLLQDSSDIKAMKEHR-KEDRGAEDSPDEWQDVNLEELDALESNLLA-------EQNSLEAQKQQQDRIAASVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFNKNKFVEYYQYVDFYNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGRGLDPLLKFSEWWHKAQNNKK--AAENPYDTKVKKKLR--KLQLTPGFPNPAVADAYLRPVVDDSRGSFLWGKPDVDKIREFCQRYFGWNRMKTDESLYPVLKQLNAHQTQLRIDSFFRLAQQEKQDAKHIKSHRLSRAVTCMLRKEREETAGELKKVP-------ETLDKANGKTQKRSQPNTR-ETSVPKRRRPS------GNG----------------------YTVVNHKL---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35689-1", "uniprot_id": "ERCC5_MOUSE", "id": "P35689-1", "name": "DNA excision repair protein ERCC-5", "aln": "MGVQGLWKLLECSGHRVSPEALEGKVLAVDISIWLNQALKGVRDSHGNVIENAHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLAKRRQRKDSASIDSRKTTEKLLKTFLKRQALKTAFRSSRHEAPPSLTQVQRQ--DDIYVLPPLP-EEEKHSSEEEDEKQWQARMDQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRR----TLFEAMPEESNDFSQYQLKGLLKKNYLNQHIENVQKEMNQQHSGQIQRQYQDEGGFLKEVESRRVVSEDTSHYILIKGIQGKKVMDVDSESLPSSSNVHSVSSNLKSSPHEKVKPEREPEAAPPSPRTLLAIQAAMLGSSSEDEPESREGRQSKERNSGATADAGSISPRTCAAIQKALDDDNDEKVSG-----SSDDLAEKMLLGSGLEQEEHADETAERGGGVPFDTAPLTPSVTEVKECVTSGSSANGQTDSAHSFTTASHRCDTPKETVSLARAVKEASQISSECEVEGRPAALSPAFIGTPSSHVSGVLSEREPTLAPPTTRTHSDQGIDIH-PEDPELQNGLYPLETKCNSSRLSSDDETEGGQNPAPKAC---------STVHVPAEAMSNLENALPSNAEERGDFQETIQLREVPEAAAR-ELISAPKPMGPMEMESEESESDGSFIEVQSVVSNSELQTESSEASTHLSEKDAEEPRETLEEGTSRDTECLLQDSSDIEAMEGHR-EADIDAEDMPNEWQDINLEELDALESNLLA-------EQNSLKAQKQQQDRIAASVTGQMFLESQELLRLFGVPYIQAPMEAEAQCAMLDLTDQTSGTITDDSDIWLFGARHVYKNFFNKNKFVEYYQYVDFYSQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGRGLDPLLKFSEWWHEAQNNKK--VAENPYDTKVKKKLR--KLQLTPGFPNPAVADAYLRPVVDDSRGSFLWGKPDVDKISTFCQRYFGWNRMKTDESLYPVLKHLNAHQTQLRIDSFFRLAQQEKQDAKLIKSHRLNRAVTCILRKEREEKAPELTKVT-------EALDDAKGKTQKRELPYKK-ETSVPKRRRPS------GNGGFLGDPYCSESPQESSCEDGEGSSVMSARQRSAAESSKISCSDVPDLVRDPPHGRQGCVSTSSS-SEDDEDKAKTVLVTARPVFGKKKL----KLKSMKRRKKKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28715-1", "uniprot_id": "ERCC5_HUMAN", "id": "P28715-1", "name": "DNA excision repair protein ERCC-5", "aln": "MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRE--NDLYVLPPLQ-EEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRR----TLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTEN-SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDS------------VPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASP-TCTNSVSKNETH-AEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQ-DLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLA-------QQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPK--IRPNPHDTKVKKKLR--TLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKGKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRR----KLRRARGRKRKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJS3-1", "uniprot_id": "F1QJS3_DANRE", "id": "F1QJS3-1", "name": "", "aln": "MGVHGLWKLLESTGKPINPETLEGKILAVDISIWLNQAVKGVRDRDGNAVQNAHLLTLFHRLCKLLFFRIRPVFVYDGDAPLLKKQTLAVRRQRREETNRESRQTSEKLLQTFLKRQAIRAALGENSQESAPSLSSVRRDEHDDIYVLPALPPEDDRQESSSEEEKDGDEALHNYSRFQEELCDNPDAVDINSEQFSLMPPEIKHEILKEMKEFSKRRR----TLLHKPPERSGEFSQYQLAGLLQRNRLNQRLECVEQEMNQRSSGGHTDQ--------QNTEIRRLVSEDSSHYILIKGGQ-KKVSAVATPAAP------ALWSSSPWEPKGRNKGKPEPLWRPVS--------------EEEENKPSSSSSSPEDQSAGAPA-----SPRTLLAIQSAMMESEDEDQQIQ------DSRSKTNIIPSSSKT----------------EEQQIQNSRTRTHVITSSSSEDED-------------------QHIQNSRARTHIITSSSEDETEIRRTSDP-----APGTTDLKLESRTPLSLASA--ASGSLEQTHTL-QQDAE-----------------SSEDESRS------------------SVILDCVRSETQRKTREEEEKEEESTVNQILQFRDSRDPSEKEEREDQPEENREKREEEEESSADESFVEVSDAE--EPPETDESHINTHQTDYNTEEKEEEVEE----EEESSAQSTDQIEDVDESVNEAPAVS-----EWEHIDTEELQLLDRELQD-------EQQTLREQHQQQQRSSSTVTGQMCQESQELLRLFGVPFIVAPMEAEAQCAALDRLDQTHGTITDDSDIWLFGGRHVYRNFFNQNKYVEHYQIVDMQNQLGLDRSKLINLAYLLGSDYTEGIPGVGYVTGMEILNEFPGAGLEPLVQLSEWWTEAQENKK--LSVNPKDTKVKKKLR--NLQIHPGFPNPAVAQAYLQPSVDQSDASFSWGRPHLDLIKEFCQSRFGWSSRKTEETLQPVLKQLQSQQTQLRIDSFFRLEQQDRQ---QIRSERLRRAVICMKRKEREEEE-EDESVS----------AQKQGRSEADEAPGPLAGGFISSDPQTS------TQGG--------------------GAKQIRAE------------------------------SSSSSSEEEAESGKGVAMVTARSVFEGKTRGRGKKLLRGRGRSKNR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07276-1", "uniprot_id": "RAD2_YEAST", "id": "P07276-1", "name": "DNA repair protein RAD2", "aln": "MGVHSFWDIAGPTARPVRLESLEDKRMAVDASIWIYQFLKAVRDQEGNAVKNSHITGFFRRICKLLYFGIRPVFVFDGGVPVLKRETIRQRKERRQGKRESAKSTARKLLALQLQ-NGSNDNVKNSTPSSGSSVQIFKPQ---DEWDLPDIPGFKYDKEDARVNSNKTFEKLMNSINGDGLEDIDLDTINPASAEFEELPKATQYLILSSLRLKSRLRMGYSKEQLETIFPNSMDFSRFQIDMVKRRNFFTQKLINTTGFQDGGAS-KLNEEVINRISGQKSKEYKLTKTNNGWILGLGANDGSDAQKAIVIDDKDAGALVKQLDSNAEDGDVLRWDDLEDNSLKIVRHESSNATTAPQKRSNRSEDEGCDSDECEWEEVELKPKNVKFVEDFSLKAARLPYMGQSLNNAGSKSFLDKRHDQASPSKTTPTMRISRISVEDDDEDYLKQIEEIEMMEAVQLSKMEKKPEADDKSKIAKP--------------VTSKGTEARPPIVQYGLLGAQPDSKQPYHVTNLNSKSESVIKRTSKTVLSEFRPPSQQEDKGAILTEGEQNLNFISHKIPQFDFNNENSLLFQKNTESNVSQEATKE--------KSPIPEMPSWFSSTASQQLYNPYNTTNFVEDKNVRNEQESGAETTNKGSSYELLTGLNATEILERESEKESSNDENKDDDLEVLSEELFEDVPTKSQISKEAEDNDSRKVESINKEHRKPLIFDYDFSEDEEDNIVENMIKEQEEFDTFKNTTLSTSAERNVAENAFVEDELFEQQMKDKRDSDEVTMDMIKEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVFLFGGTKIYKNMFHEKNYVEFYDAESILKLLGLDRKNMIELAQLLGSDYTNGLKGMGPVSSIEVIAEFGN-----LKNFKDWYNNGQFDKRKQETENKFEKDLRKKLVNNEIILDDDFPSVMVYDAYMRPEVDHDTTPFVWGVPDLDMLRSFMKTQLGWPHEKSDEILIPLIRDVNKR-----------------------KKKGKQKRINEFFPREYISGDKKLNTSKR--------ISTATGKLKKRKM----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . * ***: * :*.*** .** ::*.*: :*:*:****:* ***:**:**..*:**::*: *::::: .::.*:.*** *: :. . . .. . .*: .: : * : ** : . :.. :.:. : : : : .::: * :*. :* :: **..:: :: * :. .* :**::*: : ::* :.*:: . : * : :. * : ::: * . . : : . : . : . .:: . . . . . : * : . .. : . : . . . . . .. . . : . . : : :.::. * : . . : : . : : : :.. . . . * . : . . .. . : . . . . : : : . . : * :..: : *. . :: * *: ::.* : ** :* * **** **:*:* ********** * : . * ******::***. ::*:*:*:::::**.*: .: . *****.::*:** *******:*: :* *:.:*:: ** . * ::.:*: :.* : : * :..::*** : : .**. * :**::* **.. .* ** *.:* : * : :** *::* * *:::.:: : :.. : : : :* : *: : ", "identical_positions": 153, "similar_positions": 273, "identity": "12.5%" }, { "cls_id": "homologset.agr.HGNC:34379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNM8-1", "uniprot_id": "A0ABZ3NNM8_RAT", "id": "A0ABZ3NNM8-1", "name": "PrdX deacylase domain-containing protein 1", "aln": "-----------------MAGLELRAALEQRLGALAIRTEVVEHPEFLCVHILQVFTVEEMMPHIQHLKGAHSKNLFLKDKKKKSYWLVTVLHDRQINLNHLGKQLGVGSGNLRFADETAMLEKLKVGQGCATPLALFCD-DGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLVFVKATGHDPIILNFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D820-1", "uniprot_id": "PRXD1_MOUSE", "id": "Q9D820-1", "name": "Prolyl-tRNA synthetase associated domain-containing protein 1", "aln": "-----------------MAGSELRAELEQRLGALAIRTEVVEHP--------EVFTIEEMMPHIQHLKGAHSKNLFLKDKKKKNYWLVTVLHDRQINLNDLGKQLGVGSGNLRFADETAMLEKLKVGQGCATPLSLFCD-DGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLIFVKATGHDPIILNFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NEY8-1", "uniprot_id": "PRXD1_HUMAN", "id": "A6NEY8-1", "name": "Putative prolyl-tRNA synthetase associated domain-containing protein 1", "aln": "-----------------MAGAELGAALEQRLGALAIHTEVVEHP--------EVFTVEEMMPHIQHLKGAHSKNLFLKDKKKKNYWLVTVLHDRQINLNELAKQLGVGSGNLRFADETAMLEKLKVGQGCATPLALFCD-GGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLTFVKMTGHDPIILNFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFS2-1", "uniprot_id": "PRXD1_DANRE", "id": "Q6PFS2-1", "name": "Prolyl-tRNA synthetase associated domain-containing protein 1", "aln": "MDQSELVEAVSEAGGAAVAPVDLRKELEEFLKRLNIETTCIEHP--------EVFTVEEMMPHVSHLSGVVTKNLFLKDKKRR-VFLVCVRHDRPLALGELSRRLGAP--NLRLAEERLLLEKLRVRQGCVTPLALFLDTERSVTAVLDRELTHGGHTHIHCHPMTNSATMGITPADLLRFLEETQHTPVILSFD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* **: * * *.* :*** :***:******:.**.*. :*********:: :** * *** : *..*.::**. ***:*:* :****:* ***.***:** * .*. *** : .*** ::: *****:****::* *:* *:: * * *:**.**", "identical_positions": 88, "similar_positions": 43, "identity": "45.13%" }, { "cls_id": "homologset.agr.HGNC:3438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTU1-1", "uniprot_id": "A0A0G2JTU1_RAT", "id": "A0A0G2JTU1-1", "name": "DNA excision repair protein ERCC-6", "aln": "MPHEEIPNSTQPQGQDWLPGQHVSADRDIPAGQETAGDSEAGKCLSSPSCDHGPSTSAEACVLAATRWGPALLHIDRHQIPAVEPSAQALELQGLGVDVYDQAVLEEGVLQQVDSAMHEASRVAQRADAEKEYQSVLDDLMSCTTSLRQINKIIEQLSPQAASNRDINRKLDSVKRQKYNKEQQLKKITAKQKRLQAILGGAEVHVELDHGSLEEEDAEPGPSCLGSMLMPAQESAWEELIRTGQMTPFGTPAPQKQEKK-PRKIMLNEASGFEKYLADQAQLSFKRKKQAANKRTAKKA-VVVSESSRGPNETKPNQRSQALSQTDKRLKKHIRKLQRRALQFQGKVGLQRGKR-PLEPEERPGAEGDTEGEESGSSPTDGEEEEEQ-EEE-GVAVLSSDDISYELKPLRKGQKYEKKVPVQEID-DDFFPSSEEEDEAV---EGRGGGRKVSRRPDDGDEDYYKQRLRRWNRLRLQDKEK-LKLEDD----SEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTLIVCPTTVMHQWVKEFHTWWPPFRVAILHETGS-------------------------------------------CAHRKERLVRDIVHCHGVLITSYSYIRLMQDDISRHDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFTFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFIDSKAVYRILNGENQIFSGLVALRKICNHPDLFSGGPKNTSALPEDGL-EEEQFGYWKRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLHILEVFLRAHK-----YSYLKMDGTTTIASRQPLITKYNEDTSIFVFLLTTRVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLTSPDASQGTETSAIFAGTGSNIQTLKCHFKKRTPPVLQMD---PKRKKPLVSDTSVNGATVMEEKSQGSGATG-SVPSTESGPLKSDRHTDGSRASSVGFGEEADAGSTLEHLSGLSGD-----SPAVDHTSRLSAVASTSEKQGSSYEGEC-CQAQTGPVHLSEQTEGHFSKHKSKRK-HDAAEEETTEKCPQPKQKAKNSRHHRDAKFEGTRVPHLVKKRRYHQQTTEQESGAK--DRSSDDYVLEKLFKKSVGVHSVVKHDAIID--GSSPDYVLVEAEANRVAQDALKALRLSRQQCLGATSGVPTWTGHRGISGAPAGVKKRFGQKRNSSLPVQRPS--SLTERTQN--MKKEGEAH---TAEHFSG-KEDGASSSGAPSSSSLLARMRARNHMILPERLESDGEQLAGAAAAAAPPCSTEHDALLVDMRNFIAFQAQVDGQASTQEILQAFESKLS-VAQSCVFRELLRNLCNFHRTPGGEGIWKLKPEYC-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPZ5-1", "uniprot_id": "ERCC6_MOUSE", "id": "F8VPZ5-1", "name": "DNA excision repair protein ERCC-6", "aln": "MFHEEVPNSTHPQEQDCLPSQHANAYKDMPVGQENGGVSEAGECLSSTSCEYGPSTSAEACVLAATRRGPTLLHIDRHQIPAVEPSAQALELQGLGVDVYDQAVLEQGVLQQVDSAMHEASCVAQLADAEKEYQSVLDDLMSCTTSLRQINKIIEQLSPQAASNRDINRKLDSVKRQKYNKEQQLKKITAKQKRLQAILGGAGVQVELDHASLEEDDAEPGPSCLGSMLMPAQETAWEELIRTGQMTPFGTPAPQKQEKK-PRKIMLNEASGFEKYLAEQAQLSFERKKQAATKRTAKKA-IVISESSRAAIETKADQRSQVLSQTDKRLKKHSRKLQRRALQFQGKVGLPSGKK-PLEPEVRPEAEGDTEGEESGSSPTDGEEEEEQ-EEEEGVASLSSDDVSYELKPLRKRQKYQKKVPVQEID-DDFFPSSEEEDEAM---EGRGGGRKVARRQDDGDEDYYKQRLRRWNRLRLQDKEKRLKLEDD----SEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTIIVCPTTVMHQWVKEFHTWWPPFRVAVLHETGS-------------------------------------------YTHKKERLIRDIVYCHGVLITSYSYIRLMQDDISRHDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFIDSKAVYRILNGENQIFSGLVALRKICNHPDLFSGGPKNASGPPEDEL-EEEQFGHWRRSGKMIVVESLLKIWHRQGQRVLLFSQSRQMLHILEVFLRAHK-----YSYLKMDGTTTIASRQPLITKYNEDTSIFVFLLTTRVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLTSPDASQGTETSAIFAGTGSSIQTPKCQLKKRTSTVLGTD---PKCKKPPVSDTPANAATLIGEKPKAAGATGRSVTSGESGPFKGDHDTNGNRASSVAFGEETDAGSTLEHLSVMSGDGKHSDSPTVDHTSRPPVEASTSEKQGSSYAGAR-CQAQTEPVPMSEQMEGQFSKYKSKRK-HDASEEETTEKRPQPKQKAKNSKHCRDAKFEGTRVPHLVKKRRYRQQTSEQEGGAK--DRSSDDYVLEKLFKKSVGVHSVVRHDAIID--GSSPDYVLVEAEANRVAQDALKALRLSRQQCLGAASGVPTWTGHRGISGAPTGVKNRFGQKRDSSLPVQHPS--SLTEKTQNN-MKKEGKAH---TPEHFSG-KEDGASVSGAPSSSSLLARMRARNHMILPERLESDSEHLA--EAAAVPPCGTEHDDLLVDMRNFIAFQAQVDGQASTQEILQEFESKLS-VAQSCVFRELLRNLCNFHRTPGGEGIWKLKPEYC-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03468-1", "uniprot_id": "ERCC6_HUMAN", "id": "Q03468-1", "name": "DNA excision repair protein ERCC-6", "aln": "MPNEGIPHSSQTQEQDCLQSQPVSNNEEMAIKQESGGDGEVEEYLSFRSVGDGLSTSAVGCASAAPRRGPALLHIDRHQIQAVEPSAQALELQGLGVDVYDQDVLEQGVLQQVDNAIHEASRASQLVDVEKEYRSVLDDLTSCTTSLRQINKIIEQLSPQAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVKIELDHASLEED-AEPGPSSLGSMLMPVQETAWEELIRTGQMTPFGTQIPQKQEKK-PRKIMLNEASGFEKYLADQAKLSFERKKQGCNKRAARKAPAPVTPPAPVQNKNKPNKKARVLSKKEERLKKHIKKLQKRALQFQGKVGLPKARR-PWESDMRPEAEGDSEGEESEYFPTEEEEEEEDDEVEGAEADLSGDGTDYELKPLPKGGKRQKKVPVQEID-DDFFPSSGEEAEAASVGEGGGGGRKVGRYRDDGDEDYYKQRLRRWNKLRLQDKEKRLKLEDD----SEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQWVKEFHTWWPPFRVAILHETGS-------------------------------------------YTHKKEKLIRDVAHCHGILITSYSYIRLMQDDISRYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFVDSKEVYRILNGEMQIFSGLIALRKICNHPDLFSGGPKNLKGLPDDEL-EEDQFGYWKRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLDILEVFLRAQK-----YTYLKMDGTTTIASRQPLITRYNEDTSIFVFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLTSPDASQSTETSAIFAGTGSDVQTPKCHLKRRIQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKGAEVNAVTSNRSDPLKDDPHMSSNVTSNDRLGEETNAVSGPEELSVISGNGECSNSSGTGKTSMPSGDESIDEKLGLSYKRERPSQAQTEAFWENKQMENNFYKHKSKTKHHSVAEEETLEKHLRPKQKPKNSKHCRDAKFEGTRIPHLVKKRRYQKQDSENKSEAK--EQSNDDYVLEKLFKKSVGVHSVMKHDAIMD--GASPDYVLVEAEANRVAQDALKALRLSRQRCLGAVSGVPTWTGHRGISGAPAGKKSRFGKKRNSNFSVQHPSSTSPTEKCQDGIMKKEGKDN---VPEHFSGRAEDADSSSGPLASSSLLAKMRARNHLILPERLESESGHLQ--EASALLPT-TEHDDLLVEMRNFIAFQAHTDGQASTREILQEFESKLS-ASQSCVFRELLRNLCTFHRTSGGEGIWKLKPEYC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z974-1", "uniprot_id": "A0A8M6Z974_DANRE", "id": "A0A8M6Z974-1", "name": "DNA excision repair protein ERCC-6", "aln": "MPVEGTEDQALSP-----LSSPVS-------ALTPGAPEDNGLSIPGSSREEPAAACPETVGAQNSRKSQPLLQINRQEILSVDHSSQAAELQGLGVDVYDQDVLEQGVLQQVDRAIQEANQAAAKAEAQKEYESVLDDVRSCTSALKHINKILEQLTPHAASSKDISRKIESVKRQKENKEKQLKKIRAKQKRLQALLDGEDIQ-KLEAELLIEDDEEPGPSTLGSMLMPAQESEWEELIRTGHMTPFGSRIPQKQEKKEPRKVMLTENSGFDKYLADQALLADSRKRPIMKKKTTKKH--------SGETTPNKEKKNGSLSSKDKKLQKRMLKLQRTALRAHPKARPKVEKELPRVKKRKSDWEHASDSEGSEYVPSDELMDPEEPERDDDDELWVDDHEEYQLKPYKKKKEPKTRKPKKEDESDDYIPSSSEEEDSQ-------KGGKVKKCKDDGDIECYRQRIRKWKRQRLREKEAKREAGEEE---SDESDAEFDEGFKIPGFLWKKLFKYQQTGVRWMWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKLKTRGSNYRYAGLGPTVIVCPATVMHQWVKEFHTWWPPFRVAVLHDTGS-------------------------------------------FTSKKEKLIPEIVASHGILITSYSYIRIMQDYIQRYDWHYVILDEGHKIRNPNAGVTTACKQFRTPHRFILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYANASPVQVQTAYKCACVLRDTINPYLLRRMKADVKANLSLPDKNEQVLFCRLTEDQRQVYQTFLDSKEVYQILNGDMQVFSGLIALRKICNHPDLFTGGPRLLRGIPHDQLTEEEHFGYWKRSGKMIVVESLLRLWHKQGHRVLLFTQSRQMLEILEVFVKENG-----FSYLKMDGTTTIASRQPLIAQFNQNKDIFVFILTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKQQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDIYELFTLSSPDGSQGTETSAIFAGTGSDVQVPKRHKTS-------------------------------------------SPSQGTTRPSLSHSTDSGNRNTTSVNGLPNNNTSESP-------------NNKLESRSNANGLTSSTSKALSSMNSPQ--------------------KHREKKKHCETPEKDTIPSD-GHKRKHKKRKHSEDARFEGARISHLVKKRRYKKEEDEEKEDERKNEKRSDDYVLAKLFKKS-GIHSVMKHDTIME--ASNPDYVLVEAEANRVAKDALRALKVSRQRCRLPYS-------RGSTTATPAPVKKRFGQKKNSLLSQSSGTMTKSAEKCKDAEIVKKSVVKKPGSAAHFSG--EGAEDESGSLSSSSLLARMRARNHLKKPQSQEDEEEEST--QSVAVNAAPTEHDELLVDLRNFVAFQAQVDGQASTKEILEYFTPRLT-STQMPVFRELLNNICEFHRLPGKEGMWKLKADYR-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40352-1", "uniprot_id": "RAD26_YEAST", "id": "P40352-1", "name": "DNA repair and recombination protein RAD26", "aln": "--------------------------------------------------------------------------MEDKEQQDNAKLENNESLKDLGVNVLSQSSLEEKIANDVTN-------FSNLQSLQQEETRLERSKTALQRYVNKKNHLTRKLNNTTRISVKQNLRDQIKNLQSDDIERVLKDIDDIQSRIKELK--EQVDQGAENKGSKEGLQRPG------------ETEKEFLIRTGKITAFG----------------------------HKAGFSLDTANREYAKNDEQKD---------EDFEMATEQMVENLTDEDDNLSDQDYQMSGKE--------------------------------------SEDDEEEEN-----------DDKILKELEDLRFRGQP-------------------------------------GEAKDDGDELYYQERLKKWVKQRSCGSQRSSDLPEWRRPHPNIPDAKLNSQFKIPGEIYSLLFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLT----------GPVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQKFKMDENDLENLIMNSKPSDFSYEDWKNSTRTKKALESSYHLDKLIDKVVTDGHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAK--DLPQKKEMVLFCKLTKYQRSKYLEFLHSSDLNQIQNGKRNVLFGIDILRKICNHPDLLDRDTKRHN----------PDYGDPKRSGKMQVVKQLLLLWHKQGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGTTNIKGRQSLVDRFN-NESFDVFLLTTRVGGLGVNLTGANRIIIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQFLTNRILTDPKQKRFFKIHELHDLFSLGGENG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSTEELNEEVQKHTENLKNSKSEESDDFEQLVNLSGVSKLESFYNGKEKKENSK----TEDDRLIEGLLGGESNLETVMSHDSVVNSHAGSSSSNIITKEASRVAIEAVNALRKSRKKIT-----------KQYEIGTPTWTG-RFGKAGK---------------------IRKRDPLK-----NKLTG----SAAILGNITKSQKEASKEAR--------QENYDDGIT----FARSKEINSNTKTLENIR--AYLQKQNNFFSSSVSILNSIGVSLSDKEDVIKVRALLKTIAQFDKERKG---WVLDEEFRNNNAS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: : .*:.***:* .* **: : ::* : . ::* : . : :.: *:: .:*. : . . . : : : *. : *: **.* *.::: : :. : * .** *: * *****::*.** .:* :: . . *. :* :: *:. :..*..: ::. :: : *: .* :*: : . **** *::*:::* : * .: . : .: .**:::. **:** ::. **:**:* *:*::**: *:.***:***********:***:*.* :* : * **.:****:***:** :**: ****:*..:**. ** : : ::*: .:. :***:* :*: .* : : .*:*.:**********:: :: :**:::* :*:****:*:**** ******** *********** :** :**.:***:**: :**:*.**** .*** *.******:*:** .**:*:* ****:**. *:. * *:.*. : :* **. ::: *: **********: ..: .:* :***** **:.** :**:** :.***:******.*** *: : .**:*****.* .**.*: ::* : .: **:*****************::*:********* ************::*::***:..*:******************:*.****:**** :::::**:* . :. . :: . ..: *: : .. ** *.* . : *:: : .** :: *: . .:.:*: **:::: ..... :: **.*** :*:.**: **:: : .:*: ***: . : *.. : :::* . * :.*. * .** *. * ..: * ::* :* : : :*: .**: : *: : .* **..:. *.: * *. :: ", "identical_positions": 377, "similar_positions": 331, "identity": "24.07%" }, { "cls_id": "homologset.agr.HGNC:34383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZS67-1", "uniprot_id": "D3ZS67_RAT", "id": "D3ZS67-1", "name": "", "aln": "MGCTPSHNVIVN--SVAKSGIQFFKRPKAILPGCQWGSQKCPIPLLIQSSTFCDPGG---ELHPGARLAEETASS-RKLPDMTEGLCQLP--------ESQTFHMNKSQSRMATDISFRTEGSHRTQEVEFSGKE-GKENTPRETSERGREPKCHPSDSQDHCCQTVP---EPKGKVDFPESLVKAHQHAYAYLHTSLSRYEAIVHLVQQASQTWELLQSMLSFLLLGFEEASQLLGEISKDGEVLLREVRGDLAWPVRKGE------------PWE-HPDLLQQLLQYTVNKLQVVHSTVAALTGSFLEGSSSYLRATAGHLEGKLSTKRGIDECLLRALGQLESLTSGSSDPGLLGPPLCSEDSGIGADNESVHSVEKLGKQASWDFAAELGEWKPGTAAQGEARPSGHAWQKGPYWTGPDRPQDCPLSGPRIAKVQPAVQDEARSSNTSSTSPEAVTSRPPEAAKSIPWDSLGTEIPVQTQLSRRSSGLMGSPYLSGDEDSSPEEEDE--LGSTDLHPEPQKALPSRPQSSPDPRESLFQPYSTKLRSPQAQEMILKMKEAISERIKFVPVP-------------SRPQDWAEEEEGRSVVPPRPRSVSGCRRAPERQRRSQSEGCLKSHVEDPTLQELRRVQTDLSKRLEVFYALGATQQGQ--SREQCLPPRTSLLWPPTNCRVSPSSAISKFKASLTQNFSILPNQDKSIFQRGSPCFDSDQPCQGKAEKLPSAIFCGKKNSRAPGDNERDIRACP-TRTSVKKLIETFSP--TESPRMPRDCRNLGTSPCLRKWGVPAMPPRFPIYRGLAPLYPKPQISPAVGRDPLKLGMSWRPSAP-FPSLPPAEASEGEDIGGEMEEDLQNLPPPPLEILMDKSFTALEHPECS------LEETLLPELQEARRPKRTWASPKLKASMSPMDLLPSKGNGSSPRLQGTRPGSTSNVGNSRKLTLDLNSQQTANPSPEAEGGAQIQAPPENTAGLSKHHQKAIPRHHANPTSGQSRALEPSLARFSRDPHSPEASRKGPERSPPGVRKASPPRAQWASQGGRRLQSLPSTHGPSQPGLRAVLSSPSPPLSPRTLSPPATRKPTSPPCQYPQSNPAPG---------SPPVQRTETNTPSSASSSSPSVSPSRGSKDSSH---SEDSEGTTNKASRGTCSVLFP-ATAFCEAKSSFSTSHPQTLP----EPGGLLRTPAGGWRGSAGPRLRADSQKRTVLNALDALPFVRRTASDRQ---RQQGDPLQLPSSDWESHPCQNSSSS--SEENAKQELPPWNNSRVPELQSSSTKWTSPLELCVLGHGLQPEARPSRSQDRSQPESQPQHKEVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PAC4-1", "uniprot_id": "PCARE_MOUSE", "id": "Q6PAC4-1", "name": "Photoreceptor cilium actin regulator", "aln": "MGCTPSHNVIVN--SVAKSGIQFFKKPKAILPGCQWGSPKCPIPLLVQSSTFCDSGG---ELHLGERLVEETVSSSKKLQAMAEGVRQLPKAMEGLIPESQTFQVNKPQGHRATDISFRTEGSHGTQEVDFSGKE-SKENTPQETSKGNRESVCHQPDSQDHCRQSAT---ESKGRVDFPEPLVKAHQHAYAYLHTSLSRYEAIVRLVQQASQTWGLLRPMLNFLLLCFEEAGQLLSEISKDGDVLLQEVRGDLAWPLRKGE------------PWEQHPDLLQQLLQYTVSKLRALHGTVAALTGSFLEGSSSCLRSTAGHLEGKLSTKRGIDECLLRALGQLESLTSSHGDAGLLGPPLCSEDSGIGADNESVHSVEKLGKQASWDFAAELGEWKPGTAAQVEARPSGHAWQEGPYWTGSDRPQDCPLSSPRIAKVQPAVQDEARSASTSGAGAEAVTSGPSEAAESLPWDSLGAEIPVRTPLSR-SSGLTDAPSLSEEEDCSPEEEDE--LSSTDLHPEPQKALPSRPRSSPDTRESLFQPYSKELRNPQAQEMILKMKEAISERIKFVPEP-------------SRPQDWTEEEEGGTVVPPRPRSVSGSRGGPERQRRSQSEGCLKSHVEDPTLQELRRVQTDLSRRLEVFYALGATRQGQ--SRERCLPSRASVLWPPTNCRVSPSSAISKFKASLTQNFSILPNQDKSIFQKGSPCFDGEQPCQGKAEKLPNAIFCGKKSGRAPRDNERDIRACP-TRPSVKTLIETFSP--TESLRMPRNCRNLGSSPCLRKWGVPAMPPRFPIYRGLAPLYSKPQISPAAG---------WRPSAP-FPSLPLAEVSESEDISGDVEEDLENLPPPPLEVLMDKSFAALECPECSQPAGSSLEETLLPGLQEASHPKRTWVSPRLKASMSPMDLLPSKGSGSSPRLHSTRSGSTRIVGDSRKLTLDLNSKQTASPSSEAKSRAQIQARAETIAGFSKQHQKAIPWHHTNPTPGQSRTLEPSLARFSRDPHSSEASRKGPERSLPRVRKASPQRAQWASQGDRRLQSLPSSHGPSQPGLPAVLSSPSPPLSPRTLSPPATRKTTSPPCQHPQSNPAPG---------SPPVRRTETNTPSSASCSSPSVSPSRGSKDSIH---SEDSEATTAKASRNTCSIFYPAATSLFEAKSSSSTSHPQMLP----EPGGLLRTPTGGWRGSSGQRLRADSQKRTVLNALNPLPFVRRTASDRQ---RQQGDQLQQSRSDWEFHSCQNSSSSSSSEENPKQELPPWNNSRVPELQGSSTKRASPLELCVLGHGLQPEARMNRGQDRPQPESQPQHKEIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGG8-1", "uniprot_id": "PCARE_HUMAN", "id": "A6NGG8-1", "name": "Photoreceptor cilium actin regulator", "aln": "MGCTPSHSDLVN--SVAKSGIQFLKKPKAIRPGCQGGSERGSIPLLVKNSTCYDAGEGLAEEQPSPRRNQTTAKGLCQLMGDPASGKRKDMEGLIPGTKTSSSQLNKSQSHMAKDIPFKTQGSHGSQGADFSGDE-SEESSTQDTSKWKRTAKCHTSSTQSHCYQTIHPAHEPEGKVDFPEPLVKAHQQAYTYLHSSLSKYEAILCIIHQATQTRELLQPMVSFLLLCFEEISQLLGEISKDGEVLLQEVREDLAWPLKKRE------------PQE-QPNLLQQLLQYTVSKLQVLNGTVASLTGSFLEGSSSYLHSTATHLENKLSTKRNVDERLLRALRQLESLASGCGDPGVQGLPLCSEDSGIGADNESVQSVDKLGKQTSWDLAPEPEEWKSVTSPHTEARQSGHTWQQSPFCLGSGRPQDCLLSGAPMAKVQPRAQDEARSPCLSSTSPENITSPPLKLGTSTPCDSFGIGVSVEPHLSK-TSRPMDASSLSDSEDSSPEEEEEDKMSSMSLCAWQEKTPHSRPQSSPADRESPFQARTRRLRSLQAQEMILKMKESISERIKFVPVP-------------CGHQDWSEEEEGRTVVPPRPSTVSGSRRAPERQTRSQSESCLQSHVEDPTFQELRRVQRDLSQKLEAFYALGAKGQGQ--SQEQILQPRAAAVWPNGTCRVSPSNTTSRLKASLTKNFSILPSQDKSILQKCNPHPEDEQ---GKAGKLPNAIPSGE-VSEAAKATDWNVRGCP-TRTSVKKLIETFSP--TESLRMLGDSKDAGASPCLRNC---IMPPRFPKYTGLAPLYPKPQISPASGRESLKMGIGWKPLAPIFPPLPKAEAAKSEELSCEMEGNLEHLPPPPMEVLMDKSFASLESPESSKSTENSPKETQEPGPGEAGPTRRTWASPKLRASVSPLDLLPSKSTASLTKPHSTGPGSGRSSCQPRKPALDLSSPPATSQSPEVKGGTWSQA--EKATSLYRQPRKAIAWHHSGPPSGQNRTSESSLARP----------RQSRERSPPVGRKASPTRTHWVPQADKRRRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAPAQCKVPSPPTQHPEASPPFSIPSPSPPMSPSQEHKETRD---SEDSQAVIAKVSGNTHSIFCPATSSLFEAKPPLSTAHPLTPPSLPPEAGGPLGNPAECWKNSSGPWLRADSQRRAALCALNPLPFLRRTASDRQPGGRPQPPTLDPTSTSYESQLGQNSSSE----ESPKKDTEPGSSPCSPELQGG-TRRASPPEFCVLGHGLQPEPRTGHIQDKSQPEAQPQQEEVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KDL6-1", "uniprot_id": "A0A0G2KDL6_DANRE", "id": "A0A0G2KDL6-1", "name": "", "aln": "MGCSPSRGRTLL--PGTHESPGETQSHNGSIGDSERGNSTARPYERKFSTAECEADG------------------------------------------AASAKLSTQEININILSQAKEKQEEKREDCEKKGGK-KSKKSTKSVRVNKRKEKEIK---------------LVQEKVDFPEELVKAHQAAYGYLNPSITKYEDLLGLLDHAAQTQISLQPMVAFMVLRYEEINKGLQEIVEEGEAMFKGNGEHLAWPCEKNKSSYNAKNATTSTCSDPPPDLLQQLLQYTVQRMRQVGQSVCGIGDTALEEAVEYFSSITDILDEKLRAKRASESRLMWLLSRIEAASQK--KPSPEDSALFSEDSGLGAESESLAGSDRQRQRRESSES-------SGTICATISSPCGFTPIQRGSYRG---------------------------------------RLLKTMSSSSSLNSLDSTCTITAKDKKDTDSLLGSVSLDEGDFTNGSEKVK-----------WNEKRSKQSEASTSELRQPRRLPAKRIENPQNVEMTLKLKDAISGRIRFLPTQGPGEKAKQTESPKSSSQQWAEDGD-KSSKRPQTAASRTSKKKTTVTKRSRSADSLRNKAEDPTLIELERTQKELNQKLERMTKVKGEGNKRQCSSKKFLPCQTQNISSVTDRQRS---LTRNIFSPSNQRKACNAKVEQATTQNGTEKMDNEKGKEKDKKAPPVKGSVKIIPVPSPPPSPRQSSGLYRERNSVQKLIDTFSQGLEESKQVPESVKILGPLKGVRKCG-------VPIIPGLGPSGTSAFID----------------------NSILCGQGESQCSERTDDLDIDNLPPPPLEVIMDNSFENVQTNAKS----------ENISRGRSTLTKKTAMSQKLRASLLSVTVLPSRGN------LCKGPVSMSQVCSTQNDTREVVKGAHHDSSHETDTES------EEAASLYKQSRKIIHLRHSSDSPMEKNTSEQDNRQLS-----------SSCRSDVGEQKDNSTNETMPNSACRSQNPLTSPISRTRVLPSTPLLHRRLPSPPVLKSQPSSSTSSSPPINRKLPSTPSAG---QRTLPSTPLMQQEHTPITMTGVTYPFKAPSPPASPKVQRWSRENSTEDTSRVFSNARSVFCPASSSLFEAQSVPTPKPPQAWTS---TGSNVLPRPWG-------------ERGRLPVSARGPQPFIRRSQSDRRP--SLSMSSRVPVISVAETCGSEPAICTHGLEEGPVREDKIRSEQ---TEIRSAVRSVSHPDLCIVGQGLQREWEK-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B6U4-1", "uniprot_id": "A0ACD6B6U4_DANRE", "id": "A0ACD6B6U4-1", "name": "", "aln": "MGCSPSKGQLFSKRPALPSGPAESKKNPDLLSDGDQIQSKAEDSEELAETEIEEPAK-----------------------------------------HSEGKRHSVDDVVCDATAIVREDAAEKILEIISSHDEQRAQETLLEQQEEAVEEKKTREKQVKRKKQRKPRLRKNSHVLAKAEFVLKAHQAAYAYLNPSISKYEALLGLLGQAAQTQRSLQTTVASVVLHFEEINQALEDLAADGEQLLREHGHNMTWPASFKDYPPTAANG--QTGSPLPSELLQQMLLHSTVNMASMGDSVRCRSDSALQELAQYFGSMSELIGEKLLAKRAAEERLKQVLCHVEAAAFR--KPGPEDSALHSEDSGIGAENDCQNGSDRQRRSR---------------------------------------------------------------------------------GSSGSGANAGITSAFNNSASLDQQHASEPVSEEDEDDEEDDEDAE-------------------PEEEVSGKDELEVQEDKKIETTYGFSEADTSRPAFQGGLQEPAKAS----------------YLKRKIRRPKTADNNTLQMKPKHRHLRGPKRSQSAECLCSEEKDSDPHVKLGYQRNQHAQHWRRKNCLPEGRVR-----------------------------SKIRGGSSGAPSADRYYGLQYGSKGPFR-------------------------AAPPSSPPTFTPEPPGRNAVRRLINTFSQGVEDSSRQRLLDQRPVRARGHKKCS-------LPLLQNSR-------------------------------AALTTGADLHLLSDRPEILDLDSLPPPPPEMLMDSSYSSSAGPSAE------------EGPHEVQCRGQRTLTQRQPVPLSRANVQR------------------CSISSSRPARQDAFLG------------------------------SSIERDYTQVTEGEN-----------------------------------------ASLHTKCYPPTTPPVSRTRLPPSCPSVHHAVPSPPSTTWPPNGRWTPS---------------------------------------AKPHTLP--------------------------------PGSQSYLEARAKFCQENQPWPP----SCTSTLPRPWG-----------DPARGRVSMGHLQPSGHCPQAHSEPLP-DIRAQEGLIEDASDSTSDGTRPECEP--------------------EPADSHLNTLQPQQIAD------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**:. . . .. : . : . .: :. : : . : : . . . : :.: . . : .* ::**** ** **:.*:::** :: :: :*:** *:. : ::* :** .: * :: :*: ::: .::** . .:****:* ::. .: : :* .: *: . : : : : ** :** :. * * ::*: : ... . .* *****:**:.:. . :: : . * . . . .. . . . . : . .*. : .. . . .:.. . . : ::. :: . .. . .. : **:* .* .. :*. * : : . : .: . . : .. :. . * :*: **:*** :* : : :: .* . ::: ***** *::**.*: . . : : : ..: : ..: : . * :: . :. : . ... :: * .* * .* . * * * : : **:. . . * * : * : . . :: *: : . . . . ::. ", "identical_positions": 90, "similar_positions": 227, "identity": "6.67%" }, { "cls_id": "homologset.agr.HGNC:34385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HB5-1", "uniprot_id": "RS10B_RAT", "id": "Q66HB5-1", "name": "Radial spoke head 10 homolog B", "aln": "MVK-EKKKADKKGDKSARSPSSISDNPEAAKQEISASKQEVAPSAVIPVLETPLKQT-PKRDSEHTYQSEDETQYEEPILTKLIVESYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGDFVKNIPMNHGVYTWPDGSTYEGEVVNGMRNGFGMFKCGTQPVSYIGHWCHGKRHGKGSIYYNQEGTSWYEGDWVYNIKKGWGIRCYKSGNIYEGQWENNMRHGEGRMRWLTTNEEYTGHWEKGIQNGFGTHTWFLKRIPNSQYPLRNEYIGAFVNGFRHGQGKFYYASGAMYEGEWVSNKKQGRGRITFKNGRVYEGLFSNDHIAQFFEAEMDYSYSLDRRSDISQRSRQARGSSVSADREPETLRKLDGSESRSVLGSSIELDLNLLLDMYPEESQEEEKKQVEYAVLRNITELRRIYCFYSGLGCDHSLDNTFLMTKLHFWRFLKDCRFHHHNITLADMDRVLSVYNGIPIEEIHSPFRTILLRTFLNYLLQLAYYIHHKEFQNRSPSLFLCFTKLMAENIHPHACQVKGHLFNEQQRTLYSMNYIDKCWEIYTAYCRPNEAPPYELTMKMRYFLWMLKDFRMINKELTATKFMRVIAEDNPFVYDGMDSNFELELVFLEFFEALLCFSLCCMFDQMTRSYLKAPYDDVTTNRYGSTQTVLNQSIHR-SPSGATSHDSEVHFS-STKSSLDKIGVLPDG-KIRQSEPKLKKSLSEDKVSKMNLKAQGRGLVFMSPHGEKYEKSKDEQKEKLNMWVNNLYVFFVSVLFSAYKHEEALKEKVEENRLQEAVLAQQKQIENEELEARLN--ILREEEARRQDFELDITVLKEPPEVPAVQPLTPSPPKEDLVSMQTSKASPGKKKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PYQ0-1", "uniprot_id": "RS10B_MOUSE", "id": "E9PYQ0-1", "name": "Radial spoke head 10 homolog B", "aln": "MVK-EKKKADKKGDKSARSPSSISDNPEASKQDSNASKQEVAPSAVVPVVETPLKQA-PKRDSVQMEQSEEETQYEEPILTKLIVESYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGDFVKNIPMNHGVYTWPDGSTYEGEVTNGMRNGFGMFKCGTQPVSYIGHWCHGKRHGKGSIYYNQEGTSWYEGDWVYNIKKGWGIRCYKSGNIYEGQWENNMRHGEGRMRWLTTNEEYTGHWEKGIQNGFGTHTWFLKRIPNSQYPLRNEYIGEFVNGFRHGQGKFYYASGAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSNDHIAQFFETEMDYSQSLDRWSDASQRSRQPRGSSVSAVREPETLRKLDGSESRSVLGTSIELDLTLLLDMYPEESQEEEKKQVEYAVLRNITELRRIYCFYSGLGCDHSLDNTFLMTKLHFWRFLKDCRFHHHNITLADMDRVLSVYNGIPIEEIHSPFRTILLRTFLNYLLQLAYYIHHKEFQNRSPSLFLCFTKLMSENIHPHACQVKGHLFSEQQRTLYSMNYIDKCWEIYTAYCRPNEAPPYELTMKMRYFLWMLKDFRMINKDLTATKFMTVIAEDNPFVYDGTDSNFELELVFLEFFEALLCFSLCCMFDQMTRSYLKVPYDDITTNRYGSTQTILNQSIHR-SPSAITSHDSEVHFS-STKSSLDKIGALPDG-KIRQSEPKLKKSLSEDKVSKMNFKTQGRGLVFMSPQGEKYEKPKDEQKEKLNIWVNNLYVFFVSVLFSAYKREEMLKEKVKENQLQEAELAQQRQIENEELEARLN--ILREEEARKQDFELDITVLKEPSEIPASQPLTPSPPKEDLASIQTSKASPGKKKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RC85-1", "uniprot_id": "R10B2_HUMAN", "id": "B2RC85-1", "name": "Radial spoke head 10 homolog B2", "aln": "MVK-EKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSP-AGVPLLGMQLNEVKPKKDRQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVAPR----------LSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITELRRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEEIHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLFREQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATFMEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNKHETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYVFFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADVSSSH-LILDPPKEDVTVSPSSKTITSKKKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CH7-1", "uniprot_id": "RS10B_DANRE", "id": "Q08CH7-1", "name": "Radial spoke head 10 homolog B", "aln": "MARGDNMKSSNKSTPEPTLSKTLVESSTSSLLSESVVEPEDGQDLSSSAVCSASTVSLPPNENQPIG--EHDRCRTVPVLHSIIVERYEGEKCGEMFHGEGVAYFQGGHVYKGSFSHGLMHGYGEYIWSDGLKYQGDFKVNVPMGHGTYTWLNGSTYEGEVHQGIRHGVGMYKCVKTLTVYRGQWYLGKRQGQGEMFYNQEATSWYKGEWVNNCREGWGKRCYPSGNVYEGQWRNNVRHGEGTMRWIDLDQQYSGQWINGIQEGKGTHTWFRKRAPSSQYPRMNEYTGDFVQAMRHGQGQFLYASGALYCGQWKYDKKHGQGRYIFENGRVYEGEFSKDCMAEFPAFTPGLSGITTPFP----------------DENDSSKGASQSSSNASPLGSDMVLNIQTLLNRVSEAHREQEFKQVEFAVLRHMGLLREIYSFYSSLGHEQSLDKIFPLTHLQFSRFLLDCRVHQHGVTLAQIYSLIN---------VHSPFTAILPRECISYIIIIAYHICHKDIESSNNILAACFSKLMKQNIIPNAKSVKGHLFCHPVHAAVAMNYSDKSWEIYQALCEAHS------VFTVRQFVLMLKDLCLYDNELTVSKLIRTLSVDSPAIHDGTYSNLDLEMSFLEFFEALLG------------------CAELKGQ------------------------------------------------KIQSYDESQTDASLQDHISSLSKEKEQRQSPVLAY-----------QETELNDWMHKTQQFFNQTFLPAY----ELKVKVEEETFRLRDNTTTRYTEQLELKEKQE-----------QDADGNELCPVTTTSVTSIH---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: :: *:.:*. .. ..:: :. : . .. . * . . : . * .: *. .:* .:*** ***** ::.***.* **** .*:* **.***** * ***:*****:*** *:**.**.*** :** ***** :*:*:*.**:** . . * *:* ***:*:*.::****.*.**:*:** * ::*** *** ***:*****.:*:***** ***: :::*:*:* .***:* ****** ** .**** *** * **:. ***:*:* *****:* *:* :**:* ** *:**:**** **:* :* * . .. . :.*.. * **:.: *:: **: .* : :* ****:****:: **.**.***.** :***: * :*:*:* *** **:.*:* :***:: ::. :**** :** * :.*:: :**:* *::::. . * **:*** :** *:* .:**:** . :: :*.* :*.**** * *.. .:.:* *: ****: : :::**.:.:: .:: *. ::** **:: *: ********* ::. : **:. : . ..: .:::*.:. : : .:: :: ::* *::: ** ..:: ** :* *:. : :: : : *: **: : : :* : : ...:.: : ", "identical_positions": 279, "similar_positions": 235, "identity": "31.6%" }, { "cls_id": "homologset.agr.HGNC:34386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQN6-1", "uniprot_id": "TM14C_MOUSE", "id": "Q9CQN6-1", "name": "Transmembrane protein 14C", "aln": "MQKDSGPLMPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQD-PRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVG-------ISLLSSPHP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R701-1", "uniprot_id": "M0R701_RAT", "id": "M0R701-1", "name": "Transmembrane protein 14C", "aln": "MQKDSGPLVPLHYYGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQD-PRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGTSLLMVAKLG-------LSMLSSSHP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0P436-1", "uniprot_id": "TM14C_DANRE", "id": "Q0P436-1", "name": "Transmembrane protein 14C", "aln": "--------MAVDWAGYGYAALVASGGVIGYVKAGSVPSLAAGLVFGGLAGFGAYQTSQD-PGNIWVSLAASGTLAAIMGKRFYNSRKITPAGLIAGASVLMLAKLG-------AGMLQKPQKS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N1Z1-1", "uniprot_id": "A0A8M1N1Z1_DANRE", "id": "A0A8M1N1Z1-1", "name": "Transmembrane protein 14C", "aln": "--------MSMDWLGYGYAALITIGGIVGYAKAGSFISLVAGLMFGVAAFVGAYQMSKN-DKDIWVSLGTSGSLTALMGVRFLSSWKIMPAGFMAGASLLMFLRIG-------VKVLQSSQKKRS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6UXP3-1", "uniprot_id": "TM14E_HUMAN", "id": "Q6UXP3-1", "name": "Transmembrane protein 14EP", "aln": "MQMDPGPQVPLYWLGFVYAALAALGGISGYAKVGSVQSPSAGFFFSELAGLDASQPSRN-PKEHLSSPVYIWDLARYYANKILTLWNIYACGFSC-RCLLIVSKLGSMYGEQILSVVAMSQLGLMKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1K0-1", "uniprot_id": "TM14_DROME", "id": "Q9W1K0-1", "name": "Transmembrane protein 14 homolog", "aln": "--------MPVDWFGYVYAATVAAGGIMGYAKAGSIPSLGAGLAFGALLGYGAHLNSQD-TPRPLLQLGTSLFLAGLMGARWNRSGKLMPAGMVCMLSVAALVKNLATYN---RYLMPAGTKAP---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47131-1", "uniprot_id": "YJ55_YEAST", "id": "P47131-1", "name": "TMEM14 protein homolog YJR085C", "aln": "----------MEHPAYTLSLLTTAGGLMGYYRKGSIPSLVSGLVFGSVYGIAGYLLHMNRDGGLEMALGAS---TLLLGAGVIRG---MPSRFTKPVPVVLTALGGLG-----SYYYYNKYKEFYP-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : : **: ** : **. * :*: *. . : : . .. : : ", "identical_positions": 9, "similar_positions": 19, "identity": "7.09%" }, { "cls_id": "homologset.agr.HGNC:34388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD19-1", "uniprot_id": "D4AD19_RAT", "id": "D4AD19-1", "name": "", "aln": "--------------------------MA-LKLTLAPVHPPPIPGNYCLFPSALGY-VLALPSVVLVLSGAGEVCLLRILSAGYKLHDPSRPRAPAFSFGSRLPLRHATCGPGPSYLVPAGMTARGSVVSPAFSIYGRLSHITPVLTPGPGRYFPE---------------------------------------------------------------------RAGNVTYPSAPRHTIASRNWGIVSKQQTPGPGSYTVPSLLGSRVIG---------------------------KVSAPTYSIYGRSAVGSCFEDLSKTPGPCAYHVVNP----------------------------------------------------------------GIYKTRAPQFTMLGRTLPPK-SPKDPGPASYAVDKVV---------------------------------------WSRGSRGRG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5M8M2-1", "uniprot_id": "CMA1B_MOUSE", "id": "Q5M8M2-1", "name": "Ciliary microtubule associated protein 1B", "aln": "--------------------------MG-SEVWVGTWRPHRPRGPIAALYRGPGP-KYKLP-----------------TNTGYKLHDPSRPRAPAFSFGSRPPLRHATCGPGPSYLVPARMTVRGTVGSPAFSIYGRLSHTAPVLTPGPGRYYPE---------------------------------------------------------------------RARNVTYPSAPRHTIAPRNWGILAKQETPGPGSYTVPSLLGSRVIS---------------------------KVSAPTYSIYSRSPVGSCFEDLSKTPGPCAYHVVNP----------------------------------------------------------------MIYKTRAPQFTMLGRTLPPRENTKKPGPASYSVDKVV---------------------------------------WSRGSRGRG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MYP8-1", "uniprot_id": "CMA1B_HUMAN", "id": "A8MYP8-1", "name": "Ciliary microtubule associated protein 1B", "aln": "--------------------------MG-SDAWVGLWRPHRPRGPIAAHYGGPGP-KYKLP-----------------PNTGYALHDPSRPRAPAFTFGARFPTQQTTCGPGPGHLVPARMTVRGTDGAPAYSIYGRPRRSAPFLTPGPGRYFPE---------------------------------------------------------------------RAGNATYPSAPRHTIAPRNWGVQAEQQSPGPAAYTVPSLLGPRVIG---------------------------KVSAPTCSIYGRRAAGSFFEDLSKTPGPCAYQVVSP----------------------------------------------------------------GVYKSRAPQFTILARTSLPQDNTRKPGPAAYNVDQHRKP-----------------------------------RGWSFGIRHSDYLA-------------------------------------------PLVTDADN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQA5-1", "uniprot_id": "CMA1B_DANRE", "id": "A3KQA5-1", "name": "Ciliary microtubule associated protein 1B", "aln": "--------------------------MSPVDVWVGSWRPHKPRGPIAAMYNSPGP-TYALP-----------------GATGMNNHDPRMQKGPAFSFGIRHHNFHGNYSPGPGYLVPSNITRVGRDGTPAYSVYGRRKDIQPFQTPGPGSYSPE---------------------------------------------------------------------NATKATYLSPPAFTLSARTK-LFRNDQTPGPAAYMLPPVLGPKVVN---------------------------KTSAPNVSFSGRSAIGSFHEDLRKTPGPGTYQVVDP----------------------------------------------------------------CVYKHKGPQYSMTGRNMMPGDMTKKPGPGAHYPEMVCFTRA-------------------------------KAPSFSFGIRHSEYVA-------------------------------------------PTIVDGED-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PB71-1", "uniprot_id": "M9PB71_DROME", "id": "M9PB71-1", "name": "Mucin-1", "aln": "MNKVEFKNKNKDQGPCARVRKIRPINMG-GNVEQRPWTPTVRIGKIAAETTNPGPATVQLP-----------------TLIGSKVPDSKKKAAPSYSFGHKLGGKYDTSGPGPAQYNVTGMRAKGRDYPRAATLQSRPKELTRFSNPGPGEYDVVPAAKAVIDATPKYTFGQRPVALKTFQIPGPNYYQVVPLDVVKRRAPRYSFRIKVNVYLVNNPAPNSYCPEKVTQSKKNAPRYTFGRRTK-IEHDQGTPAPGAYCPEKVKLNKTPEFSFGIKHHEQRPDYTPAPGTYKPEQVVLEHIPAYSFG----LKTKHIQVSDTPAPGAYSPEKSRLHSAPAYSIAGKASQDVVDCTPAPGAYEPEKCVLSRTPAFSFGHRAELAKSSDTPAPGTYNPEKVRLDHTPAFTLSGRPETRS-VSETPAPGSYAPEKYRNDRTPAFTFGGKHEQRLESSTPAPGDYCPEKVRHDHNPAFSFAGRHDLHKPSDTPAPGAYDTEKVRQDHNPAFSFAGRHDLHKPSETPAPGAYSPEKVRQDHNPAFSMAGKHSQKVTSDSPAPGDYCPEKVRLDHTPAYSFGVKSDPKVENNTPAPGDYHPEKVRQDHNPAYSFAGRHDLQKPDNTPAPGAYFPEKVRLDHNPAFSMAGKYDAKVTNDTPAPGDYSPEKVRQDTNPAYSFAGRHDLHKPSETPAPGAYSPEKVRLDHNPAFTMAGKHDQKILNGTPAPGDYSPEKCRLDHTPAYSFGGKNDPKVENNTPAPGDYHPEKVRLDHNPAYSFAGRHDLQKPSDTPAPGAYSPEKVRQDHNPAFSMAGKPVEKLTNGTPAPGDYSPEKVRLNHTPAYTFGGKNDPKVENNTPAPGDYHPEKVRQDHNPAFSFAGRHDLHKPNDTPAPGAYCPEKVRQDHNPAFSMAGKYTQKVANDTPAPGDYSPEKVRLDHTPAYTFGGKNDPKVESNTPAPGDYHPEKVRQDHNPAFSFAGRHNLQKPSDTPAPGAYSPEKVRQDHNPAFTMAGKHDPKVSNDTPAPGDYSPEKVRLDYTPSFTFAGKNNPKVENDTPAPGDYHPEKVRQDHNPAFSFAGRHDLHKPSDTPAPGAYSPEKVRQDHNPAFSMAGKYIEKITNGTPAPGDYCPEKVRLDHTPAFTFGGKNDPKVENNTPAPGDYHPEKVRQDHVPAFSFAGRHDLHKPNETPAPGAYSPEKVRQDHNPAFTMAGKHDPKVTHDTPAPGDYHPEKVRLDHNPAFSFAGRHDLHKPSETPAPGDYFPEKVRQDFNPAFTFAGKHDPRSLSESPAPGDYSPEKVRLDHAPAFSFGGKHDPKTEHLHPAPCDYAPEKVRLDHTPAYTIAGRPAADHVSQTPAPCDYHPEQCQVDSTPAFTFGMRLGRERISDTPAPSAYEPEKHSLHSTPAYSFGTKSDIRVTTDAPAPGHYHPEQCKLDSSPAYSFGLKTVPTASLPEPRGAYIEDRIVQRRERRLASPVRNNAECTTTTTNHTNNNAGSSTTTTTTTTTTTKTFINGVEQPELQKKETTKQVNGTHKELKSAPQAPLSNGNIVSNGNHSKMVSTTTRIQEVAHGQKESGNLKVVASGKSDASATKAAAVSHQTVVQADGAIVTSGQSSRMQTVKYAVEASSVQEKIISS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCJ6-1", "uniprot_id": "Q9VCJ6_DROME", "id": "Q9VCJ6-1", "name": "", "aln": "---------------------------------------------MAVRPFGPGPGVYMLP-----------------PTVGYDKHDNRKQRLPQYSFGMRTRAPGEDLGPGPGAYKVDKLTRYGTSKGLEFSMAPRTNVIDKRSSPGPGAHDVH---------------------------------------------------------------------NRPFFKGVNAPSYSMGLRTD-FNFKKDGPGPNAYKYEVNAVRPG--------------------------------VPSYSMG----LQTKILNKTNSPGPAAYGG-------------------------------------------------------------GDIN---VKLTRAPIYSMQPRTTIPG-ENVGPGPNYYDLMYYRPGKS--------------------------------GPGYSFGVRHHQFAP-------------------------------------------PMIVRCDNM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ** * * * ::** : .***. : * :: * .**** : . . ..* .::. *. . .. *.* :* * *: : : .:*.* :* : : * ::: * *.* : :* . * ", "identical_positions": 33, "similar_positions": 41, "identity": "2.03%" }, { "cls_id": "homologset.agr.HGNC:3439", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7B8-1", "uniprot_id": "G3V7B8_RAT", "id": "G3V7B8-1", "name": "DNA excision repair protein ERCC-8", "aln": "MLSFLSARQS--GLEDPLRLRRAQSTRRVLGLELNKDRDVERVHCS------------GVNTLDIEPVEGRYMLSGGSDGVIVLYDLENASRQP------------------------------------------------------------YYTCKAVCSVGRSHP-----------------------DVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHR------QEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAVESAN-------------TAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWN---SSSGDNTLVNYGKVCNSSRKGLKFTVSHGCNSEFVFVPYDSTIAMYAVYSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPASYEPVPDDDDEAPTKSRLNPAFTDAWSSSDEDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFD5-1", "uniprot_id": "ERCC8_MOUSE", "id": "Q8CFD5-1", "name": "DNA excision repair protein ERCC-8", "aln": "MLSFLSARQS--GLEDPLRLRRAQSTRRVLGLELNKDRDVERIHGS------------GVNTLDIEPVEGRYMLSGGSDGVVVLYDLENASRQP------------------------------------------------------------HYTCKAVCSVGRSHP-----------------------DVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHR------QEILAVSWSPRHDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAAESAN-------------TAHNGKVNGLCFTSDGLHLLTIGTDNRMRLWN---SSSGDNTLVNYGKVCNDSRKGLQFAVSCGCSSEFVFVPHGSTIAVYAVHSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPPSYEPVPDDDDEAPAKSQLNPAFADAWSSSDEDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13216-1", "uniprot_id": "ERCC8_HUMAN", "id": "Q13216-1", "name": "DNA excision repair protein ERCC-8", "aln": "MLGFLSARQT--GLEDPLRLRRAESTRRVLGLELNKDRDVERIHGG------------GINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQS------------------------------------------------------------YYTCKAVCSIGRDHP-----------------------DVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHR------QEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESAN-------------TAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWN---SSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVPSLYEPVPDDD-ETTTKSQLNPAFEDAWSSSDEEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12021-1", "uniprot_id": "RAD28_YEAST", "id": "Q12021-1", "name": "Radiation-sensitive protein 28", "aln": "MDPFLEFRVGNISLNEFYRRTIQSEFERILEDPLSNMKNYRFSKQSNYSTKEKTPLSIGVNCLDIDDTG-QVLLGGGDDGSLSIWGLDESLHRNDEGEQELINKRLNYIKRQPHQSDDEPAQIMGYKNKRTRINDNNTMRLVHSFQTQRNKYRMYRQSSAAVPVQRSHISNKTDSPIGFSETLSETDSEASISHHKYGITTLKWYKADNGMFFTGSNDKTVKIWDTNRFEAVQDINLGYKINQIDNN-VVDDSSLLVVASEDYYPRLIDLRTMNSGVTALGMGNQTRMQSEILCCKFNPVREQIIACGDMEGGVKLWDLRMRNRLYSELKRNKNRFKTINNDDNDDQSDVYFSSNQSKAHLRCCSDIVWNSEGSELCSVGMDGKLNVWRPFTEILQPEGLASYSQLGTQDLSRIKYKKRVSRR-----LLWFDKFLLCITDNGEVEIYNTEEKKLWNKLEYPMVNQVKKNQASHCQFSSMIVQT--NIMNSVGLKLFFGTNNNTVSDGGSIFECS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **. * .*:: * .. .*:* *.: :: . : . *:* ***: . : :*.**.** : ::.*::: :: : ..*. .: *.* . *:*.: *::** *.*** :.* ***:*:**** :::.: :*: .: . . . . . .*:.*.:.. :* **:: ... * .***. .:.* : *:* .. :. *****:* . *.:::.: . :. * .** ..: :.*:* .* ::* *.::.:*. . : *..*.:: ... . ::: . : ..: : . .** . . * : : * . : .*:: : : : :. . * :. *. * : . ", "identical_positions": 80, "similar_positions": 156, "identity": "15.5%" }, { "cls_id": "homologset.agr.HGNC:34390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQV6-1", "uniprot_id": "MLP3B_MOUSE", "id": "Q9CQV6-1", "name": "Microtubule-associated protein 1 light chain 3 beta", "aln": "MPSEKTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETFGTAMAV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62625-1", "uniprot_id": "MLP3B_RAT", "id": "Q62625-1", "name": "Microtubule-associated protein 1 light chain 3 beta", "aln": "MPSEKTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETFGTALAVTYMSALKATATGREPCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NCE7-1", "uniprot_id": "MP3B2_HUMAN", "id": "A6NCE7-1", "name": "Microtubule-associated protein 1 light chain 3 beta 2", "aln": "MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVCASQETFGMKLSV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38182-1", "uniprot_id": "ATG8_YEAST", "id": "P38182-1", "name": "Autophagy-related protein 8", "aln": "--MKSTFKSEYPFEKRKAESERIADRFKNRIPVICEKAE-KSDIPEIDKRKYLVPADLTVGQFVYVIRKRIMLPPEKAIFIFVN-DTLPPTAALMSAIYQEHKDKDGFLYVTYSGENTFGR---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.***.. .**:* : . * ::. .:**** *: : :.::* :** *:*** .:.:.::: :**:*: * .::*:*::** .:: ..:: :* :*:..:*:*****:. :.::*** ", "identical_positions": 38, "similar_positions": 58, "identity": "26.76%" }, { "cls_id": "homologset.agr.HGNC:34391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LXH1-1", "uniprot_id": "F1LXH1_RAT", "id": "F1LXH1-1", "name": "", "aln": "MSENGKEVSSQAAKTESSTQTPSHWESIHSKPRDQLKKRSSRKK-AFKILQEKMLKLQCVFMDHFLQRTSQQMQCLPPGDQQCTRASRKQEKKMGFLLSQIINHIWSNTVKKLKFKVPPLPCSDSRCGIKAGHQALSSWQTGQPRPRLGDFEDAFADRTLSKRGTGIYEFYHLSFQGYEAYQTDKYHQDKNPSGYINLSTSENKLCLDLITARLTQCDMNFLDEAQLQYSDWKGEPSLREELASFLTHYCKAPTPLDPENVVVLNGCSSVFSSLVMVLCDPGDALLIPTPCYSGFTFSSYLYSKVELIPVYLESQVTETNKYSFQLTVDKLKLTLTQAKKKGKKVKGLVLINPQNPLGDVYTQGSLQEYLVFAKKHKLHVIMDEIYMLSVFEPTVTFHSILSIENLPDPNMIHMIWGTSKDFGMSGIRFGVLYTHNKEVASAMKAFGYHHSVSGIIQYKLRQLLQDKEWINKVYLPKNHSRLREAYSYVTKMLEDLKIPFCNCGSGLFVWINLKAYLNPCTFDQEQILHQRFQDKKLLLSSGKSFMCIEPGWFRLVFAEKHPQLQVVSGRQGSVEDPELPPLRPRGRVRTPSLCPRQVARGQATPVSRKYSPKNTARENPRSKVGAAIRHCTPKRPGSQPGSLNRFLPLGLEILSAVTLQTLWFRKTRAGPADHSVLVASFGLIFCLPQKDSTVPTTCTGSASTQDMESGYGDDLQGECLRKPDQKQPKLYGVGDPTATFSSDSFCLSSRGRVIKWFWDSAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLTQNDMLHVEPSLLQYPDWRGHRFLRKEVARFLSFYCKSPAPLKPENVVVLNGCASLFSALATVLCEPGEVLLIPTPYYGAITQHIYLYGNIRLAYVYLDSKVTGLNTRPFQLTVEKLEMALQGVNSEGVKVKGLILINPQNPLGDIYSPEELQDFLGFAMRHKLHVIMDEVYMLSVFEESLGYRSVLSLERLPDPQRTHVMWATSKDFGMSGLRFGVLYTENQHVATAVASLCRYHGLSGLVQHQMAQLLQDHDWISQVYLPENHARLKAAHTYVSEELRALGIPFVSRGAGFFIWVDLRKYLREGTFEEEAMLWRRFLDNKVLLSSGKTFECKEPGWFRVVFSDKENRLRLGMQRMRQVLKGQSQMVEDASRCHTQELQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UX83-1", "uniprot_id": "1A1L2_MOUSE", "id": "Q3UX83-1", "name": "Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2", "aln": "MSENRNEGSSQAAKANSDTQTPSHFKVTHPRLRDQLKKKSSKKK-GFKFVQEKMLKFQHVIRNQFLQQISQQMQCVPPGDQQCTQTSRKR-KKMGYLLSQMVNFLWSNTVKKLKFKVP-LPCLDSRCGIKVGHQTLSPWQTGQSRPSLGGFEAALASCTLSKRGAGIYESYHLSFQSYEAYQADKYHKDKNPSGYINLSTSENKLCLDLITARLTQSDMNLLDEAQLQYSDWKGQPFLREELASFLTHYCKAPTPLDPENVVVLNGCSSVFASLAMVLCDPGDALLIPTPCYNGFVFSSHLYSKIELIPVHLESQVPRSNLDSFQLTVDKLKLALTQAKKKAKKVKGLVLINPQNPLGDVYTQSSLQEYLVFAKTHKLHVIMDEIYMLSVFEPSVTFHSVLSIKDLPDPNMTHMIWGTSKDFGMSGIRFGVLYTHNKEVASAMKAFGYHHGVSGITQYKLCRLLQDKEWISKVYLPKNHSRLQKAYSYITKILKDLKIPFYNGGSGLFVWINLKAYLSPCTFDQEQILHQRFRDKKLLLSSGKSYMCIEPGWFRLVFAETHLHLQVAMDR----------------------FCHVLAEHKKHEK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4AC99-1", "uniprot_id": "1A1L2_HUMAN", "id": "Q4AC99-1", "name": "Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2", "aln": "---------------------MSHRSDTLPVPSGQRRGRVPRDHSIYTQLLEITLHLQQAMTEHFVQLTSRQGLSLE--ERRHTEAICEHEALLSRLICRMINLLQSGAASGLELQVP-LPSEDSRGDVRYGQRAQLSGQP-DPVPQLSDCEAAFVNRDLSIRGIDISVFYQSSFQDYNAYQKDKYHKDKNTLGFINLGTSENKLCMDLMTERLQESDMNCIEDTLLQYPDWRGQPFLREEVARFLTYYCRAPTRLDPENVVVLNGCCSVFCALAMVLCDPGEAFLVPAPFYGGFAFSSRLYAKVELIPVHLESEVTVTNTHPFQLTVDKLEEALLEARLEGKKVRGLVLINPQNPLGDIYSPDSLMKYLEFAKRYNLHVIIDEIYMLSVFDESITFHSILSMKSLPDSNRTHVIWGTSKDFGISGFRFGALYTHNKEVASAVSAFGYLHSISGITQHKLCQLLQNTEWIDKVYLPTNCYRLREAHKYITAELKALEIPFHNRSSGLYVWINLKKYLDPCTFEEERLLYCRFLDNKLLLSRGKTYMCKEPGWFCLIFADELPRLKLAMRR----------------------FCDVLQEQKEALIVKQLEDAMRE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . . .* : : .:.: :. : * *::* .: ::*:* *:* .: ::: *.: :: :. *:.:::* : *.:.. *:::** **. *** .:: *::: . *. :. * *.. * *:.. ** ** .* *: ***.*:*** ****:***. *:***.*******:**:* ** :.*** :::: ***.**:*:* ****:* ***:**:*** ************.***.:*.*******:*:*:*:* *.**.*** **:*:*****:***:*. :* .********: :* :*: :.***:*************:*: .** :** *** ::****:*********: ::****:**::.***.* *:*********:**:***.***********:.**** *.:*** *:** :***:.***.*****.* **::*:.*:* *: *:*** * .***:****** **.****::*::*: ** *:***** **::** ***** *:**: :*::. * :* : : ", "identical_positions": 290, "similar_positions": 162, "identity": "24.56%" }, { "cls_id": "homologset.agr.HGNC:34393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2Q6-1", "uniprot_id": "F1M2Q6_RAT", "id": "F1M2Q6-1", "name": "", "aln": "--MSLQATPTLLQLAMQSLLRDEAVAISALPDLPMELFPPLFKDALTHKRSNILRRMVQVWPFPCLPLGGLMKMKAPYLDVLQTILDGIDGLLDQNIHPSNYRLRILDLRALHKTFWTVWAGDKTASCISEAKCRRRSQRRGLETVAKPESLKVFIDLCLKPRALNACLSYVLLWARKRKALLQLGCKKLKINTIALQKNVKVLELLDLDCMEEVEVCCTWKLSTLAIFAPYLGQMKNLLSLILSHIHVPASISPEEKNQLVSQFTSQFPNLQCLQELSLDSACFLKGHMDQVFRCLEAPLEMLSITDSQLSESDLKALSQCPGIYQLKHLNLSGVILTNINPEPLRVLLERVAATLRILDLENCMIKDSQLSVFLPALSQCVQLIMFNYLRNPISVAALESLLLHTSKLSCLGLEMYSTPWEIFGAQSDSYHKRLDELREELSKTMMHLEHTRTVWFSVAPC-----LPNDNQVI---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3QJZ6-1", "uniprot_id": "PRA22_HUMAN", "id": "A3QJZ6-1", "name": "PRAME family member 22", "aln": "MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKT--PDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEK-QPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFISDG-CRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****. **:** **** *:*:*** * :** ******* :*:* :*.::*: ***.*********.*** * *::*: ::**** ** *:::* .::*::*:** :.:.***:*:* :. ** .** .:*:: . .* * :.****:*:*** : :: **:. *.::*:. ::* *.*: :::: : ::** : *.:: :*: . :. *: **.**:** .*::*. :*.:.::***::*:* : .*: ** * : .**::**:**::***.:*** *::* . *.: ***.*.: *.: ***:**** * *. ****.***:*****: * * :* *:**:* *:***** * :* * : * *: .*:.** **.:** *.** *.:* * :. :. : * *: ** : : .:...: ::*. ..* *.:: : ", "identical_positions": 191, "similar_positions": 158, "identity": "39.38%" }, { "cls_id": "homologset.agr.HGNC:34395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W3S3-1", "uniprot_id": "Q9W3S3_DROME", "id": "Q9W3S3-1", "name": "", "aln": "MSAERNKSGEVRSAAGGLELASASGASASETDNVSALELQSNKRMLYFSDG-VMEELSSGSEDEADAEMGDKCYDVHLNESEMPLGPRLRYKASRMGNRFLAGIDYVGGGLAHLLGITSSKYASELENYHRAKEHGDEDLDNWHPRAMSTTTSSSNNNSSGNNNRNETIVLCEPTRSEATLPPTRQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6PVY3-1", "uniprot_id": "F177B_HUMAN", "id": "A6PVY3-1", "name": "Protein FAM177B", "aln": "--------------------MEIDGFQQLDLEKSVPSKKTTPKRIIHFVDGDIMEEYS--TEEEEEEEKEEQSTNSTLDPSKLSWGPYLRFWAGRIASTSFSTCEFLGGRFAVFFGLTQPKYQYVLNEFYRIQNKKSDNKS--ERRGSKAQAAEVPNEKCHLEAGVQEYGTIQQDVTEAIPQ----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* . : :: . : : **:::* ** :*** * :*:* : * ::. : *: *::. ** **: *.*:.. :: :::** :* ::*:*..** *::::* ::: .:: . . *. .: ::. *:.. : : : :** ", "identical_positions": 34, "similar_positions": 65, "identity": "18.28%" }, { "cls_id": "homologset.agr.HGNC:34396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02631-1", "uniprot_id": "ONCO_RAT", "id": "P02631-1", "name": "Oncomodulin", "aln": "MSITDILSAEDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEFQEMVHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51879-1", "uniprot_id": "ONCO_MOUSE", "id": "P51879-1", "name": "Oncomodulin", "aln": "MSITDILSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQLKDIFQFIDNDQSGYLDEDELKYFLQRFQSDARELTESETKSLMDAADNDGDGKIGADEFQEMVHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CE71-1", "uniprot_id": "OCM2_HUMAN", "id": "P0CE71-1", "name": "Oncomodulin-2", "aln": "MSITDVLSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***:*********************************:**:*:*********** :***:***:*:*.************* ************:********", "identical_positions": 96, "similar_positions": 11, "identity": "88.07%" }, { "cls_id": "homologset.agr.HGNC:34397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZV5-1", "uniprot_id": "D3ZZV5_RAT", "id": "D3ZZV5-1", "name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "aln": "MAEAALDAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSFSYLRATVGSTEVSVAVTPDGYADAVRGDR----FVMPAERRLPVSHVLDVLEGQAQHPGVLYVQKQCSNLPTELPQLLSDIES-HVPWASESLGKMPDAVNFWLGDAAAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVV---DEEAMEK-VPWIPLDPLAPDLARYPSYSQARALHCTVRAGELLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDSLTRAAGLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C872-1", "uniprot_id": "JMJD7_MOUSE", "id": "P0C872-1", "name": "Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7", "aln": "MAEAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRATVGSTEVSVAVTPDGYADAVRGDR----FVMPAERRLPISHVLDVLEGRAQHPGVLYVQKQCSNLPTELPQLLSDIES-HVPWASESLGKMPDAVNFWLGDASAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVV---DEEAMEK-VPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C870-1", "uniprot_id": "JMJD7_HUMAN", "id": "P0C870-1", "name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "aln": "MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDR----FMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLES-HVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVV---DEEAMEK-VPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLYLPALWFHHVQQSQGCIAVNFWYDMEYDLKYSYFQLLDSLTKASGLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TCB7-1", "uniprot_id": "A0AB32TCB7_DANRE", "id": "A0AB32TCB7-1", "name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "aln": "-----MDEVKECLRDFPKEARELYLNDAVPYLDEPLSPLQFYRDWIGPNKPCIIRNAFNDWPALSKWNPTYLREKVGSKVISVAVTPNGFADAVNGNR----FVMPEERQMSFSSLLDIVEGKIKSSAVFYVQKQCSNLMEEIPELTGDVQT-HIPWMSEALGKLPDAVNFWLGEESAVTSMHKDHYENLYCVISGQKEFVLLPPTDRPFIPYELYQPATYRQKDDGTFEIV---DEENSPK-VPWIPLDPLKPDFERFPSYRHAKALHCTVKAGEMLYLPSLWFHHVRQSHGCIAVNFWYDMEYDIKYNYFQLVEALTNAVGSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU77-1", "uniprot_id": "JMJD7_DROME", "id": "Q9VU77-1", "name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "aln": "-----MSEVERALDVLLQEAEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIRKALN-WPAIGKWTPKYLIEALGDRSVDVAITPNGYADGLATQNGQEYFVLPLETKMKLSEVVRRLDDPTG--AVHYIQKQNSNLSVDLPELAADLRVSDLDFAQQSFNKPPDAVNFWLGDERAVTSMHKDPYENVYCVISGHKDFVLIPPHQLSCVPRGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYPEYARAKPLKVRVHAGDILYLPNYWFHHVSQSHKCIAVNFWYDLDYDSRYCYYRMLEQMTSARSG-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *. * : *.:* : * **. :.* * *:: *:* :**:*:: ***: **. *: :*. :.**:**:*:**.: :. *::* * :: .* :: ::. .* *:*** *** ::*:* *:. .: : .:::.* *********: ****:*** ***:***:**.*.*:: ** : . :* :* ...*: .:.* * : *** : . *:.:*** **: ::*.* :*:.*: *:**::**** ***** **: *********::** :* *::::: :* * . ", "identical_positions": 120, "similar_positions": 103, "identity": "36.92%" }, { "cls_id": "homologset.agr.HGNC:34399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A3R7-1", "uniprot_id": "A0A8I6A3R7_RAT", "id": "A0A8I6A3R7-1", "name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "aln": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDG----RSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CD94-1", "uniprot_id": "UQCC3_RAT", "id": "P0CD94-1", "name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "aln": "MEAARKALAVVAVLGAGGGVGSILFALVTPGELQKQLMLQEMPERDSRRRDEAVRTKELVMATLKDAAATKENVAWRRNWTVRGDG----RSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2T4-1", "uniprot_id": "UQCC3_MOUSE", "id": "Q8K2T4-1", "name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "aln": "MEVARKALVAVAVLGGGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRDEAVRTTELVMATLKDAAATKENVAWRRNWTVSGDG----RSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UW78-1", "uniprot_id": "UQCC3_HUMAN", "id": "Q6UW78-1", "name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "aln": "MDSLRKMLISVAMLGAGAGVGYALLVIVTPGERRKQEMLKEMPLQDPRSREEAARTQQLLLATLQEAATTQENVAWRKNWMVGGEGGAGGRSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DFP2-1", "uniprot_id": "UQCC3_DANRE", "id": "B3DFP2-1", "name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "aln": "MSGMR-ILTGSVALG---GLTYAIWIIFSPGEERKKEILKSLPEANPVRMEETRKRNAIMLQVLKDAAETNDNIAR-------GFG----SQK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * * . ** *: : :.:*** :*: :*:.:* :. : : : ::: .*::** *::*:* * * . ", "identical_positions": 20, "similar_positions": 28, "identity": "21.51%" }, { "cls_id": "homologset.agr.HGNC:344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43865-1", "uniprot_id": "SAHH2_HUMAN", "id": "O43865-1", "name": "S-adenosylhomocysteine hydrolase-like protein 1", "aln": "-MSMPDAMPLPGVGEELKQAKEIED-AEKYS--------------------FMATVTKAPKKQIQFAD--DMQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--EVSPREKQQTNSKGSSNFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80SW1-1", "uniprot_id": "SAHH2_MOUSE", "id": "Q80SW1-1", "name": "S-adenosylhomocysteine hydrolase-like protein 1", "aln": "-MSMPDAMPLPGVGEELKQAKEIED-AEKYS--------------------FMATVTKAPKKQIQFAD--DMQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--EVSPREKQQTNSKGSSNFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFN2-1", "uniprot_id": "SAHH2_RAT", "id": "B5DFN2-1", "name": "S-adenosylhomocysteine hydrolase-like protein 1", "aln": "-----------------------------------------------------------------------MQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--EVSPREKQQTNSKGSSNFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N1TYR5-1", "uniprot_id": "A0A8N1TYR5_DANRE", "id": "A0A8N1TYR5-1", "name": "", "aln": "MTDCGEDAKLEATKQASKEFKESENVAEKYSAMTATKHSDVNMNVGELSAAFTAVPTHKSVKKIQFANQEDKQEFSKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--ETSPREKSQVNSKGSSDFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKVAGCTHITAQTAVLIETLVALGAQCRWTACNIYSTQNEVAAALAESGVSVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPSVFKKVRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCSALKALGAIVCVTEIDPICALQACMDGFRVVKLNEVVRQMDMVITCTGNKNVVTREHLDRMKNGCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRVILLAEGRLLNLSCSTVPSFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPNFDAHLTELSDEQAKYMGLNKNGPFKPNYYRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50245-1", "uniprot_id": "SAHH3_DROME", "id": "P50245-1", "name": "Adenosylhomocysteinase-like 2", "aln": "MAKMPETTFADLSLAD------------------------------------------------------------KTAVKKSS-IEARRFSDVSTCSFSSTC-FTGSSDE-EDVSPKDNHQRNSAGGTDFCVKSI-SKSAFGRREIEIAESEMPGIMTLRKRAKDEKPLKGANIVGCTHVNAQSAVLIETLVQLGATVRWAACNIYSTQNAVAAALAEAGIPIFAWRGETEEEFWWCLDRAIYSDGWQPNLILDDGGDATHLMLKKYPDYFKAIRGIVEESVTGVHRLYMLSKGGKLTVPAINVNDSVTKNKFDTFYTCRDSILDSLKRTTDIMFGGKQVVICGYGDVGKGCAQSLKGQGCIVYVTEVDPICALQAAMDGFRVVRLNEVIRTVDVVVTATGNKNVITRDHMNRMKNGCILCNMGHSCSEIDVNGLHTPELTWERVRSQVDHIRWPDGRMIILLAEGRLVNLSCSTISSFVVSVASSTQALALIELFSAP-GRYKSDVYLLPKKMDEYVASLHLATFDAHLTELTDEQSKFMGLNKAGPFKANYYRY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZX9-1", "uniprot_id": "SAHH2_DROME", "id": "Q9VZX9-1", "name": "Adenosylhomocysteinase-like 1", "aln": "MNNLADTVVVDPGFGGGDKQQQAGPAPQDAS----------------------VVVPPPATKQ-------------SSALKKTSRYRSRSLSASSTDSFSSAS-YTGSSEDGDDVPPREKVQKNSKGSSDFCVRNIGAQHAFGRREIEIAEQEMPGIIALKKRAAEDKPLKDAKIVGCTHINAQTAVLIETLVELGASVRWAACNIYSTQNEVAAALAESGIPIFAWRGETEEDFWWCIDRCVNAENWQPNMILDDGGDATHLMLKKYPTMFKLVKGIVEESVTGVHRLYQLSKAGKLTVPAMNVNDSVTKTKFDNLYSCKESILDSLKRSTDVMFGGKQVVVCGYGDVGKGCAQALKGQGCIVYITEIDPICALQASMDGFRVVKLNEVIRNVDIVVTATGNKNVVVREHMDKMKSGCIVCNMGHSNTEIDVNGLRTPDLTWEKVRSQVDHIIWPEGKYIILLAEGRLVNLSCSSIPSFAVSITSATQALALIELFNAPPGRYKSDVYLLPKKMDEYVASLHLPTFDAHLTELSDEQAKYMGLNKAGPFKPNYYRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *. :* :* ** *:**:. :*.**:: :..*::: * ** *.::***:.* : **********.:*..:::*:*** :*** .*::.****:.**:******* *** **:********* *******:*:.:***:**:*::****:**.: :.**.*:******* ** : **** ** ::************** ***.*** ***:******** ***.:* *::****.***:**:********:****:*****. :**. *.** :**:********.*******:****:* :*:*:*.******:.*:*:::**..**:****** :**** .*:**:****:*******: **:*: ::*******:*****::.:*.:*::::*********:.** ****.******************..********:*:*:*::**** ****.*****", "identical_positions": 306, "similar_positions": 124, "identity": "54.94%" }, { "cls_id": "homologset.agr.HGNC:34401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L6I4-1", "uniprot_id": "A0ABK0L6I4_RAT", "id": "A0ABK0L6I4-1", "name": "", "aln": "MAQSDFLYPQNPRRRQEVNRLHQQLLDCLSDCFQVTNKLTGLLNAHLGCRLAFIEMRSDETIKRNCDLIIQAVTKIQKELQKVDEALKDKLEPTLYRKLRDIKERETEKIAIVQKVISVILGEATAAASAVAVKLVGSNVTTGIISKLASVLTHIGTSILGSIGVAVLSLGIDMVVQAILGAVERTQLQSAIQSYEKHLTEFKAASEKYHHAIAEVTDAVKRQLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQM7-1", "uniprot_id": "SMCO3_MOUSE", "id": "Q8BQM7-1", "name": "Single-pass membrane and coiled-coil domain-containing protein 3", "aln": "MAQSDFLYPQNPRRRQEVNRLHQQLLDCLSDSFQVTNKLTGVLNTHLGCRLAFIEMKSDGTIKENCDIIIQAMTKIQKELQKIDEALKDQLEPTLYRKLQDIKERETEKIAIVQKVISVILGEATSAASAVAVKLVGSSVTTGIISKLVSVLAHIGTSLLGSIGVAVLSLGIDMIIQAILGAVERTQLQAAIKSYEKHLEEFKAASAKYHHAITEVATAVKRQLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RU48-1", "uniprot_id": "SMCO3_HUMAN", "id": "A2RU48-1", "name": "Single-pass membrane and coiled-coil domain-containing protein 3", "aln": "MAQSDFLYPENPKRREEVNRLHQQLLDCLSDSFDVTNKLTEVLNMHLGCRLASIEMKRDGTIKENCDLIIQAIMKIQKELQKVDEALKDKLEPTLYRKLQDIKEKETDKIAIVQKVISVILGEATSAASAVAVKLVGSNVTTGIINKLVTVLAQIGASLLGSIGVAVLGLGIDMIVRAILGAVEKTQLQAAIKSYEKHLVEFKSASEKYNHAITEVINTVKHQMK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:**:**:***************.*:****** :** ******* ***: * ***.***:****: ********:******:*********:****:**:*****************:************.******.**.:**::**:*:*********.*****:::*******:****:**:****** ***:** **:***:** :**:*::", "identical_positions": 177, "similar_positions": 38, "identity": "78.67%" }, { "cls_id": "homologset.agr.HGNC:34403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUX1-1", "uniprot_id": "D3ZUX1_RAT", "id": "D3ZUX1-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSSGDDQQSQAFTKPTFTEAQASALVESIFGFKVSKIQPLPSYDDQNFHVHISRSQE----TTDDPVEYVLKISNTKSSQTPDLIEMQNHIIMFLRAAGFPTASVCRTKGDNTISLMSIDSGSEIKSYLVRMLTYLPGRPIAEVATSHQQLYEIGRLAARLDKALEDFHHPKLNLLHRENFIWNLKNVPLLENYMGALSQSRNREIVEQVIQLFKEEVMTKLSHFRECINHGDLNDHNILVDLSKSASGDAVYQVSGILDFGDMSYGYYVFEVAITIMYMMIESTSPIQVGGHVLAGFESVIPLTAVERDALFLLVCARFSQSLVMATYSCQLYPENKEYLMITAKTGWKHLQQMFDMGKKAVEEIWFETAKSYEAGISM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U5V2-1", "uniprot_id": "HYKK_MOUSE", "id": "Q5U5V2-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSSGAGWQSQASAKPVFTEAQASALVESVFGFKVSKIQPLPSYEDQNFRVHIARGKE----TTDDPVEYVLKISNTESSQTPELIEMQNHVIMFLRAAGFPTASVCRTKGDNTISLISIDSGSGVKSYLVRMLTYLPGRPIAEVAISHQQLYEIGRLAAQLDKALEEFHHPKLSLFHRENFIWNLKNVPLLEKYMGALSQSRNREIVEQVIRMFKEEVMTKLSHFRECINHGDLNDHNILVDLSKSASGEGVHQVSGILDFGDMSYGYYVFEVAIVIMYMMIESTNPIQVGGHILAGFESVIPLTAVERQALFLLVCSRFSQSLVMAAYSCQLYPENKEYLMITAKTGWKHLQQLFDMGQKAVEEIWFETAKSYESEISM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RU49-1", "uniprot_id": "HYKK_HUMAN", "id": "A2RU49-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTK-------DGPTEYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKSYLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKNVPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRECINHGDLNDHNILIESSKSASGNAEYQVSGILDFGDMSYGYYVFEVAITIMYMMIESKSPIQVGGHVLAGFESITPLTAVEKGALFLLVCSRFCQSLVMAAYSCQLYPENKDYLMVTAKTGWKHLQQMFDMGQKAVEEIWFETAKSYESGISM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WFT6-1", "uniprot_id": "HYKK_DANRE", "id": "A8WFT6-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSTKE-------SKPNLSHSQVTDVVKRLYGLTASVVRPLPSYDDQNFYVAPSEGG-----------EFVLKVMNSADSENVAVIELQTQSMNFLHQRGLPAQTALPTLTGQLMSLEEFDCGFGTQIYLVRLLTYLPGTTIAKITCSPQILYDVGKMAATLDTVLLQMEHPNTRVLQRERFIWKLTSIPLLNQYVHVMDGDPVQKIVKGVIEKYQVQVMPKLPLFRECINHGDFNDHNLLVK----PDGPSKYKISGILDFADMSCGYFIFELAITIMYMMIESPTPLDVGGPVVAGWESVFPLNEAERDSLYWLVMCRFCQSLVLARYTVIQQPENEEYLMITSRKGLRHLSRLWELGKDEVERRWFQSAQQFRQI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8PV77-1", "uniprot_id": "A0A2R8PV77_DANRE", "id": "A0A2R8PV77-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSTKE-------SKPNLSHSQATDILKRLYGLTTSVIRPLPSYIDQNFYVASSEGG-----------EYVLKAMNSADSQDIAVIKVQTYSMAFLNQRGLPAQIALPTLTGQMMSLEEIDCGFGTQTYLVRLLTYMPGTTICKISINTQILYDIGKMAATLDTVLLQMEHPNISVLQRDNFIWSLTSIPLLYQYIHVMDGDPVQKVVKAVIEQYQVQVRPKLPLFRKCINHGDLNDRNLLVK----PDGPSKYAISGILDFADMSCGYFIFELAITIRYMMTESPNPLDVGGPVVAGWESVFPLNEAERDSLYWLILCRFCQSLVIARYTVIQQPENEEYVRMASKNCVQHLSRLWELGKDEVERRCFQNAAQFSQS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ68-1", "uniprot_id": "Q9VJ68_DROME", "id": "Q9VJ68-1", "name": "Hydroxylysine kinase", "aln": "MEQWNNVELTNMSKKSYTLNHAYDAAEKLNKENTAKSSNGNGTSADESTAADGDLLKPGSDVRPKVEPEDVESLLRRLYGITISEVKEIVAYDDRNFFVKEDSNVKNPLIVTHCPHGYVLKILNSLDSKKEDFVDAQNQMLLYLGKHSVKCPRPVANATGKYYSVERLNG----NSNVVRLLEFIPGEIFHQVPVTKHLLYRSGEYLARLDRALKNFTH---QAYESHKTLWMLQSVPELRQFLYVVKDQEQRLICDEVIDAFEAKVLSQLPSMEHQIIHGDFNEQNIVVEQ---VPNQTEYTIKGVIDFGDTSKSPLIFEIGIALTYMILQAN-DLANGGIFLSGYTSLNPIENSELALLKYCVTARFVQSLVMGLYTHTLHPTN-EYLLVTQEKGWKLLQKLWRESFDDIDELWASTGHQYLTQSNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* . :. ::. ::*:. * :: : :* *:** * :*** *: *: .:. *. : :* .. . .: *: .: : :**:* ::** : ::. . : ** *. * ** .* : * . .. :* * .:* * ::: .: . : : . ** :: :* .:*. :.. * ***:*::*:::. . : :.*::**.* * . :**:.*.: **: :: : ** .::*: *: *: * * : .** ****:. *: * * :*: :: .. : *.::: . . ::. ... .: ", "identical_positions": 71, "similar_positions": 128, "identity": "16.55%" }, { "cls_id": "homologset.agr.HGNC:34404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Q2-1", "uniprot_id": "KNOP1_MOUSE", "id": "Q9Z2Q2-1", "name": "Lysine-rich nucleolar protein 1", "aln": "----------------------------------------------------MVSKTQKADLGPQLPEKKKKKKKKKRVVANVSEPETQYSVLNSNDYFIDASPPRATSPSNNVDEVQIPEISLSKRKKKKK-SCSTHLEECLG-AEPTRARQK-KSPSPRRQALEQSAEGLIREKKKKRRKSLSKAASQGSGLKTSPDPKHAKEVSKAGRKSKKQRKEKK-VPDTEALPPQDAWLYEAGDSLHS---CLEGAEAEEQAALGQKRKQGSPRDHNMKKKKK--THQEGDILLVNSRVS--VENSLKKGSKK-SVKSEALEFVPI-DSPKAPGKKKVKSKKKVEQPVGEGLAVKRKKKKKKRKENG------VKEDPWQEEKEESDTDLEVVLE--KKGNMDETCIDQVRRKALQEEIDRESGKTEASEPKKWTVGLSVKTEASEPKKWTGTQFGQWDTAGFENEEQKLKFLKLMGGFKHLSPSFSRPPSMTIRSNMALDKKSSEMLQQSLQQDYDRAMSWKYSH---GAGLGFNSEARKVFYIDRNASKSIKLQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AUQ0-1", "uniprot_id": "A0A8I6AUQ0_RAT", "id": "A0A8I6AUQ0-1", "name": "", "aln": "MDAVSTATQGAAKLRPGRRTISRGRARNSKLTSGSRLRGCSRGDAWPANRPVMVNKTQKEDLGPRLPEKKKKKKKKK-KVANVSEPETQYSVLNNNDYFIDVSPPRATSPFNNVGEVQVPEMSLGKRKKKKK-SCSTHLDEYLGKDEPTWTRQI-KSPSPRRQVLEQSAEGLIREKKKKRRKSLSKVASQGSGLKTSPDSKHAKEVSKAGRKPKKHRKEKK-LPDMEAFPPQDSWIPEAGDALHS---CLEGAEAEEQAALGHKRKQGSPRDHSMKKKKKKKTHQEGDILPVNSKIS--MENSLKKGSKK-SVRSEALDFIPI-DSLKAPGKKKVKSKKKVEQPVGEGLAVKRKKKKR-RKESG------VKEDPWQEEKEESDTDLEVVLE--KKGNMDEACIDQVRRKALQEEIDRESGKTEVSEPK----------------KWTGTQFGQWDTAGFENEEQKLKFLKLMGGFKHLSPSFNRPPSMTVRSNMALDKKSSDTLQQSLQQDYDRAMSWKYSR---GAGLGFNSEARKVFYIDRNASKSIKLQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1ED39-1", "uniprot_id": "KNOP1_HUMAN", "id": "Q1ED39-1", "name": "Lysine-rich nucleolar protein 1", "aln": "----------------------------------------------------MITKTHKVDLG--LPEKKKKKKVVK-------EPETRYSVLNNDDYFADVSPLRATSPSKSVAHGQAPEMPLVKKKKKKKKGVSTLCEEHVEPETTLPARRTEKSPSLRKQVFGH-LEFLSGEKKNKKS---PLAMSHASGVKTSPDPRQGEEETRVGKKLKKHKKEKKGAQDPTAFSVQDPWFCEAREARDVGDTCSVGKKDEEQAALGQKRKRKSPREHNGKVKKKKKIHQEGDALPGHSKPSRSMESSPRKGSKKKPVKVEAPEYIPISDDPKASAKKKMKSKKKVEQPVIEEPALKRKKKKK-RKESG------VAGDPW---KEETDTDLEVVLE--KKGNMDEAHIDQVRRKALQEEIDRESGKTEASETR----------------KWTGTQFGQWDTAGFENEDQKLKFLRLMGGFKNLSPSFSRPASTIARPNMALGKKAADSLQQNLQRDYDRAMSWKYSR---GAGLGFSTAPNKIFYIDRNASKSVKLED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A4H3-1", "uniprot_id": "B8A4H3_DANRE", "id": "B8A4H3-1", "name": "", "aln": "------------------------------------------------MAVGRLAKEKKKKIKVKEEEENTDSVKCHDVSVQTAIKQELLDVNDGGEKKKKKKKKLKQELDANNSLVESCDVSVQTTVKTEQIDTNNSVAPEKTKKKKKKIKEEEQIQEEAHIVSKKKKVKKDEAVEGIKKKKKKKKETEVKEEEEEADLGPAVETVNDKKKKRKRKLEEDIIKQELNAEVEDGVIKKKKRKKDVD-ECVEVEHKVKKKKKKQSVVEEAPENISSNEKPEKKSKKKKKKLESKSLPHANEDNSSDKKMKK-KKKLESKSLPDANGENSSDKKMKKKKKNKGKTEADDDVEEKPERTDNNNKSSGKNTNKTLKADPEEYFRKTASRANDVVFLSAKPGNQDEISIDQARRLALQKEIDKESQPK--------------------------PAFGQWGTASFDSSDRQAKFLRLMGGFKKSTQTGNES---AGRLNMAMGKEGQQTLQQGLLGEFERAQNRHMDFRNKGAGLGFSAPSNKKFAIDTNARNSIRFDD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* .: *::... : : .* :..: . . . . : ::.: . *.:: . .. :. : . : . : : : :. . : ..* . * . :* :*:: *:. : :* : : . * . :: :. . :*.: . : * : ::: . * :* :.* * ** : *: . .. .: * * *.*:* : . : * ::... .*..* : ** :: :. :**: * ** ** ***.** ***:***:** . . ****.**.*:..::: ***:******: : : ... * ***:.*:. : ***.* :::** . : . ******.: ..* * ** ** :*::::*", "identical_positions": 92, "similar_positions": 147, "identity": "16.61%" }, { "cls_id": "homologset.agr.HGNC:34407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "--------MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRR--------QGAHICSGSLVADTWVLTAAHCFEKAAATELNS--WSVVLGSLQ-REGLSPGAEEVGVAALQLPRAYNHYS-QGSDLALLQLAHPTTHT---PLCLPQPAHRFPFGASCWATGWDQDTS------DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGG-PQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIIS-FASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEPGSCLANISQPTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "--------MRQSWRPELLIVGAVVVIEGLQAAQRACGQRGPGPPEPQEGNTLPGEWPWQASVRR--------QGVHICSGSLVADTWVLTAAHCFEKMATAELSS--WSVVLGSLK-QEGQSPGAEEVGVAALQLPKAYNHYS-QGSDLALLQLTHPTVQT---TLCLPQPTYHFPFGASCWATGWDQNTS------DVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGG-AQPGEQGPCQGDSGGPVMCREPDGHWVQVGIIS-FTSKCAQEDTPVLLTDMAVHSSWLQAHVHEAAFLVQAPGVVKMSDENSCVACGSLRSAGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGRQTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLGLTQK-AGINYPQTVPVTVLGPMACSRQHAAPGGTGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISNLDWQVYFAEEPEPEAETGSCLVNSSQPASC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VQA0-1", "uniprot_id": "Q9VQA0_DROME", "id": "Q9VQA0-1", "name": "trypsin", "aln": "---------MFSKCFHLLLA--VHLLISP---VVPVLLEPSERIIGGSSMDIT-DVPWQVSLQY--------YGEHFCGGSIYSKTIIITAAHCIK--EGERS------IRAGSS----LHDSGGVVVGVEAYIIHPQFDKHN-MENDVAVLKLSSPLSFS-DSIQTIPLAETDPPTSSSALATGWGRGNFL-----IRPRQLQGVEILIRPLIVCKLKYGNG--------VFNEDICAG---RMGKGGCYGDSGGPLVFN-----GQLVGITSRTGNIVCLG--SSLYASVARYRNWILSAIDVLHFQAPATNV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ99-1", "uniprot_id": "Q9VQ99_DROME", "id": "Q9VQ99-1", "name": "trypsin", "aln": "---------MFIESFLLLLA--LDFLSAG---QVN---RWEQRIIGGEPIGIE-QVPWQVSLQY--------FGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAGSA----LTDSNGTLVDVAALIIHEEYAFDL-NINDIAIVRLSTPLEFT-SKVQPIPLAKTNPYPRSIALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSCRLFDPS-------------LLCAG---TYGRTACHGDSGGPLVVN-----KQLVGVVS-WGRKGCVS--SAFFVSVPYFREWILNAIASIQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPY7-1", "uniprot_id": "Q8IPY7_DROME", "id": "Q8IPY7-1", "name": "trypsin", "aln": "---------MCLRLLLSILVSIAGLACAA---RIP---GPEERIVGGSYIPIE-YVPWQVSVQN--------NSLHCCGGVIYSDRAILTAAHCLSNVTVTDLS-----VRAGSS----YWSKGGQVLKVLKTIAHPKYVPKLYNPYDIAVLILEAPLRLG-GTVKKIPLAEQTPVAGTIVLTSGWG--YTRENSSFLWP-ILQGVHVAILNRTDCLKAYKHVN-------ITIDMICAD---GQRWDTCQGDSGGPLIETTKGGHRQLIGMVS-WGDGCGTN--PGVYEDIAFFHNWIKYTVKKNIYKSIVKI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA2-1", "uniprot_id": "TRYDT_DROME", "id": "C0HKA2-1", "name": "Trypsin delta", "aln": "-----------MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTIS-SFPWQISLQR--------SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQ-----IRAGSS----YWSSGGVTFSVSSFKNHEGYNANT-MVNDIAIIKINGALTFS-STIKAIGLASSNPANGAAASVSGWGTLSY---GSSSIPSQLQYVNVNIVSQSQCASSTYGYG-----SQIRSTMICAA---ASGKDACQGDSGGPLVSG-----GVLVGVVS-WGYGCAYSNYPGVYADVAALRSWVISNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA3-1", "uniprot_id": "TRYGT_DROME", "id": "C0HKA3-1", "name": "Trypsin gamma", "aln": "-----------MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTIS-SFPWQISLQR--------SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQ-----IRAGSS----YWSSGGVTFSVSSFKNHEGYNANT-MVNDIAIIKINGALTFS-STIKAIGLASSNPANGAAASVSGWGTLSY---GSSSIPSQLQYVNVNIVSQSQCASSTYGYG-----SQIRSTMICAA---ASGKDACQGDSGGPLVSG-----GVLVGVVS-WGYGCAYSNYPGVYADVAALRSWVISNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA4-1", "uniprot_id": "Y0031_DROME", "id": "C0HKA4-1", "name": "Trypsin delta/gamma-like protein CG30031", "aln": "-----------MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTIS-SFPWQISLQR--------SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQ-----IRAGSS----YWSSGGVTFSVSSFKNHEGYNANT-MVNDIAIIKINGALTFS-STIKAIGLASSNPANGAAASVSGWGTLSY---GSSSIPSQLQYVNVNIVSQSQCASSTYGYG-----SQIRSTMICAA---ASGKDACQGDSGGPLVSG-----GVLVGVVS-WGYGCAYSNYPGVYADVAALRSWVISNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8J8-1", "uniprot_id": "A1Z8J8_DROME", "id": "A1Z8J8-1", "name": "trypsin", "aln": "-----------MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTIS-SFPWQISLQR--------SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQ-----IRAGSS----YWSSGGVTFSVSSFKNHEGYNANT-MVNDIAIIKINGALTFS-STIKAIGLASSNPANGAAASVSGWGTLSY---GSSSIPSQLQYVNVNIVSQSQCASSTYGYG-----SQIRSTMICAA---ASGKDACQGDSGGPLVSG-----GVLVGVVS-WGYGCAYSNYPGVYADVAALRSWVINNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35004-1", "uniprot_id": "TRYB_DROME", "id": "P35004-1", "name": "Trypsin beta", "aln": "-----------MLKFLILLSAVACALGGT--IPEGLLPQLDGRIVGGTATTIS-SFPWQISLQR--------SGSHSCGGSIYSARVIVTAAHCLQSVSASSLQ-----IRAGSS----YWSSGGVVAKVSSFKNHEGYNANT-MVNDIAVLHLSSSLSFS-STIKAIGLASSNPANGAAASVSGWGTESS---GSSSIPSQLRYVNVNIVSQSRCSSSSYGYG-----NQIKSSMICAF---ASGKDSCQGDSGGPLVSG-----GVLVGVVS-WGYGCAAANYPGVYADVAALRSWVINNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04814-1", "uniprot_id": "TRYA_DROME", "id": "P04814-1", "name": "Trypsin alpha", "aln": "-----------MLKIVILLSAVVCALGGT--VPEGLLPQLDGRIVGGSATTIS-SFPWQISLQR--------SGSHSCGGSIYSANIIVTAAHCLQSVSASVLQ-----VRAGST----YWSSGGVVAKVSSFKNHEGYNANT-MVNDIAVIRLSSSLSFS-SSIKAISLATYNPANGASAAVSGWGTQSS---GSSSIPSQLQYVNVNIVSQSQCASSTYGYG-----SQIRNTMICAA---ASGKDACQGDSGGPLVSG-----GVLVGVVS-WGYGCAYSNYPGVYADVAVLRSWVVSTANSI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35005-1", "uniprot_id": "TRYE_DROME", "id": "P35005-1", "name": "Trypsin epsilon", "aln": "-----------MLKFAVLLSVLACALAGT--IPDGLLPQLDGRIVGGYETSID-AHPYQVSLQR--------YGSHFCGGSIYSHDIVITAAHCLQSIEAKDLK-----IRVGST----YWRSGGSVHSVRSFRNHEGYNSRT-MVNDIAIIRIESDLSFR-SSIREIRIADSNPREGATAVVSGWGTTES---GGSTIPDHLLAVDLEIIDVSRCRSDEFGYG-----KKIKDTMLCAY---APHKDACQGDSGGPLVSG-----DRLVGVVS-WGYGCGDVRYPGVYADVAHFHEWIERTAEEV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42278-1", "uniprot_id": "TRYT_DROME", "id": "P42278-1", "name": "Trypsin theta", "aln": "--------MHRLVVLLVCL-AVGSACAGTVGVSNGDPFEREGRIVGGEDTTIG-AHPYQVSLQTK-------SGSHFCGGSLINEDTVVTAAHCLVGRKVSKVF-----VRLGST----LYNEGGIVVAVRELAYNEDYNSKT-MEYDVGILKLDEKVKET-ENIRYIELATETPPTGTTAVVTGWGSKCYF--WCMTLPKTLQEVYVNIVDWKTCASDEYKYG-----EIIYDSMVCAY---EKKKDACQGDSGGPLAVG-----NTLVGIVS-WGYACASNLLPGVYSDVPALRKWILNASETL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5U8-1", "uniprot_id": "Q9W5U8_DROME", "id": "Q9W5U8-1", "name": "Peptidase S1 domain-containing protein", "aln": "--------MNRLLLSVVALVALAASCHGNPGLD--FPF---GRIVNGEDVDIE-NYPYQVSVQTT-------KGSHFCGGSLIDSETVLTAAHCMQSYAASELQ-----VRVGST----SRSSGGEVVTVRAFKYHEGYNSKL-MINDVAIIKLSSPVRQT-SKIRAIELADSEAVSGTNAVVSGWGTTCFL--FCSS-PDTLQKVEVDLLHYKDCAADTYNYGS----DSILETMVCAT---GEKKDACQGDSGGPLVAD-----NKLVGVVS-WGSGCAWTGYPGVYADVASLRSWIVDTTDSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52905-1", "uniprot_id": "TRYI_DROME", "id": "P52905-1", "name": "Trypsin iota", "aln": "-----------MAVYGIVATVLVLLLLGD-----ASDVEATGRIIGGSDQLIR-NAPWQVSIQI--------SARHECGGVIYSKEIIITAGHCLHERSVTLMK-----VRVGAQ----NHNYGGTLVPVAAYKVHEQFDSRF-LHYDIAVLRLSTPLTFG-LSTRAINLASTSPSGGTTVTVTGWGHTDN-----GALSDSLQKAQLQIIDRGECASQKFGYGA----DFVGEETICAA---STDADACTGDSGGPLVAS-----SQLVGIVS-WGYRCADDNYPGVYADVAILRPWIVKAANAI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42280-1", "uniprot_id": "TRYZ_DROME", "id": "P42280-1", "name": "Trypsin zeta", "aln": "MSSSWIVGLLAFLVSLVALTQGLPLLEDLDEKS-----VPDGRIVGGYATDIA-QVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGT-VASQYK----VVAGTN---FQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLALEQPIEGTVSKVSGWGTTSPG----GYSSNQLLAVDVPIVSNELCDQDYEDFGD--ETYRITSAMLCAGKRGVGGADACQGDSGGPLAVR-----DELYGVVS-WGNSCALPNYPGVYANVAYLRPWIDAVLAGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8J7-1", "uniprot_id": "A1Z8J7_DROME", "id": "A1Z8J7-1", "name": "trypsin", "aln": "-----------MCIPLLLLAIGFSSVISISGQ-------PEGRIINGTTVDIA-RHPYLVSLRYR--RDNESSYMHECAGVIISEQALITSAQCLYGLPEETKLV----AVAGAN---TRNGTDGFIYPVANWTHHPNYDP-VTVDNDIGVLLLDTTLDLTLLGISSIGIRPERPAVGRLATVAGWGYREEW----GPSSYKLEQTEVPVVSSEQCTQIYGAG-------EVTERMICAGFVVQGGSDACQGDTGGPLVID-----GQLVGLVS-WGRGCARPNYPTVYCYVASFVDWIEETIAAAGVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7JPN9-1", "uniprot_id": "Q7JPN9_DROME", "id": "Q7JPN9-1", "name": "trypsin", "aln": "--------MSRILVVFLVLGVGCSLADPIYRNEEVHIPKLDGRIVGGQDTNIT-QYPHQISMRYRG--------NHRCGGTIYRSNQIISAAHCVNTLSGPENLT----IVAGSSNIWFPTGPQ-QELEVREIIIHPKYRT-LNNDYDAAILILDGDFEFN-DAVQPIELAKERPDHDTPVTVTGWGTTSEG----GTISDVLQEVSVNVVDNSNCKNAYSIM--------LTSRMLCAG-VNGGGKDACQGDSGGPLVYN-----NTLLGIVS-WGTGCAREKYPGVYCSVPDVLDWLVETVADKESVGKIDFL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6TEK4-1", "uniprot_id": "VKOR1_RAT", "id": "Q6TEK4-1", "name": "Vitamin K epoxide reductase complex subunit 1", "aln": "------------------------------------------------------------------------------MGTTWRSPGRLRLALCLAG------------------------------LALSLYALHVKAARAR-NEDYRALCDVGTAISCS------------------RVFSSRWGRGFG------LVEHVLGADSILNQSNSIFGCMFYTIQ-------LLLGCLRGRWASILLILSSLVSVAGSLYLA-----WILFFVLYDFCIVCITTYAINAGLMLLSFQKVPEHKVKKP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . *. : .: : : *. * : : . . . .*.: : ", "identical_positions": 5, "similar_positions": 18, "identity": "0.86%" }, { "cls_id": "homologset.agr.HGNC:34408", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810A5-1", "uniprot_id": "MACA1_MOUSE", "id": "Q810A5-1", "name": "Microtubule-associated tyrosine carboxypeptidase 1", "aln": "MVLDSGTQVYEQAPPRPPAGSPSQHHKLKPSNGNGPPLYPWPESLGMPLALAVPSALQQQTMWQTFSKLHLEQSSHMRRSESTYSVNSTGRRGR---GKAPIGRGCDPGG-TLRPAASLPHIAKIRKDVGSSSSKSPCMLVALRPTNMDQEREKFFQSHYTYNPQFEYQEPMPMSVLEKYQEASAQFMNQAVGIIEAVLEKFGTYENFEAATGGQLLTKCQIWSTVRKYMQKEGCVGEIVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRLQYGLQPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLAQYVQDEGVRWEYCVRAKRGQTDTSQPGCFSKDQVYLDGILRILRHRHTIDFQLLTSLGKVSYEDVEQLRPYGVLDNTRVPHFMKDLERYRQQLEHIMTTNRLDEAELGRLLPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V7A9-1", "uniprot_id": "MACA1_RAT", "id": "Q4V7A9-1", "name": "Microtubule-associated tyrosine carboxypeptidase 1", "aln": "MVLDSGTQVYEQAPPSPPASSPSQHHKLKPSNRNGPPLYPWPQSLAMPLALAVPSALQHQTMWQTFSKLHLEQRSHMKRSESTYSVNSTGRRGR---GKAPLGRGCDPGGGTLRPAASLPHIAKIRKDVVSGSNKSPCMLVALRPTNMDQEREKFFQSHYAYNPQFEYQEPMPMSVLEKYQEASGQFMHQAVGIIKAVLEKFGTYENFEAATGGQLLTKCQIWSIVRRYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRQQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLEQYVQDEDVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGILRILRHRQTIDFQLLTSLGKVSYEDVEQLRPHGVLDKTRVPHFMKDLDRYRQQLEHIMTTNRLDEAELGRLLPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68EN5-1", "uniprot_id": "MACA1_HUMAN", "id": "Q68EN5-1", "name": "Microtubule-associated tyrosine carboxypeptidase 1", "aln": "MVLDSGAQAYDQAPPSPPTSPPSLRHRLKPSDRDGPPLYPWSQSLALPLALAVPPALQPQPEQQPFSQMLLGHRGHMRRSESTYSVNSTGRRGRGTLGRPPPGRGRNPGGGTLRPAASLPHIAKTQRDAGHIASKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCAGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNARQPWHNAEGRLRYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLERYVQDADVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMATNRLDEAELGRLLPD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*.*:**** **:..** :*:****: :*******.:**.:*******.*** *. *.**:: * : .**:**************** *:.* *** :*** ************* ::*. :.***************:**:*******:************ :***** ***.**::******:**********:***************** **:*******.**:*****************************************************:*****.:*** :***:**********************************:**:********** :**** .***************** **************:******:**** *************::***:****:*******:** **********:***************", "identical_positions": 384, "similar_positions": 59, "identity": "81.53%" }, { "cls_id": "homologset.agr.HGNC:34410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A198-1", "uniprot_id": "D4A198_RAT", "id": "D4A198-1", "name": "Neuralized-like protein 4", "aln": "MAAGSGGSGGSGAGPGPGPGPGGGGGPGSSGPGLGSSGGLGSGGELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLVEGDRVGVERTATGELRLWVNGRDCGVAATGLPARVWAVVDLYGKCTQITVLPPEP----------------------GFSPSTPISTPPLEPLAPPEDSALSEQGTSVDEAFMVSPAQARPETFPNSLDSHNDFASMELSEVVSNAILSAYN-------------------------------------------GGLLNVSLSSPPAADGLASSGSATSP-ILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDR---LRRN-------------------------NAILRALSPE---------GALRRAAPAASAEP---ERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDD-VEVPPVSEPLPEGNNQMSPSSPASAVGG---SDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNT--ATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRVAG----YAHGLVFSTKELKAEEVFEVKVEELDEKWAGSLRLGLTTLAPEDMGPGAGSG-PGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLGVGSRVGIRRCADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRSVAIVSSTRLEEPEGTQPPSPSSDTGSEGEEDEEGEEHGLRGQNQVGVMPTALEFLENHGKNILLSNGNRTATRVASYNQGIVVISQPLVPHMLVQVRIDFLNRQWTSSLVLGVITCPPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHINGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVSPDPGTASGKT---------------AGTQGDMEKADMVDGIKES----VCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKR----------SLCYCESCRKLRGDEAHRRRGE------------------------------------------------PP---------------------------------------------------------------------------REYALPFGWCRFNLRVNPHLEAGTLTKKWHMAYHGSSVAVVRRVLDRGELG----------------------------------------------------------AGTTSILSCRPLKGEPGVGFE-----------------------------------------EPGENCAPPREEQPPAVLLSPSLQYAGAETLASKVQFRDPKSQRTHQAQVAFQVCVRPGSYT-------------------------PGPPSAALRELPDQHFSPS------ELEWVTKEKGATLLYALLVRVE--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCX5-1", "uniprot_id": "NEUL4_MOUSE", "id": "Q5NCX5-1", "name": "Neuralized-like protein 4", "aln": "MAAGSGGSGGSGAGPGPGPGPGGGGGPGSSGPGLGSGGGLGGGGELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLVEGDRVGVERTATGELRLWVNGRDCGVAATGLPARVWAVVDLYGKCTQITVLPSEP----------------------GFSPPTPVPTPPLEPLAPPEDSALLEQGTSVDEAFMVSPAQARPETFPNSLDSHNDFASMELSEVVSNAILSAYN-------------------------------------------GGLLNVSLSSPPAGDGLASSGPATSP-ILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDR---LRRN-------------------------NAILRALSPE---------GALRRAAPAAQAEP---ERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDD-VEVPPVSEPLPEGNNQMSPSSPSSAAGG---SDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNT--ATEKSFPLHSPVAGVAHRFHSMCGKNVTLEEDGTRAVRVAG----YAHGLVFSTKELKAEEVFEVKVEELDEKWAGSLRLGLTTLAPEDMGPGAGSG-PGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLGVGSRVGIRRCADDTMHILVDGEDMGPAAAGIAKNVWAVLDLYGPVRSVAIVSSTRLEEPEGTQPPSPSSDTGSEVEEDDEVEEQGLRGQNQVGIVPTALEFLENHGKNILLSNGNRTATRVASYNQGIVVISQPLVPHMLVQVRIDFLNRQWTSSLVLGVITCPPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHINGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVSPDPGTASGKI---------------AGTQGDMEKADMVDGIKES----VCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKR----------SLCYCESCRKLRGDEAHRRRGE------------------------------------------------PP---------------------------------------------------------------------------REYALPFGWCRFNLRVNPHLEAGTLTKKWHMAYHGSSVAVVRRVLDRGELG----------------------------------------------------------AGTTSILSCRPLKGEPGVGFE-----------------------------------------EPGENCAPPREEQPPPVLLSPSLQYAGAEMLASKVQFRDPKSQRTHQAQVAFQVCVRPGSYT-------------------------PGPPSAALRELPDQHFSPS------ELEWVTKEKGATLLYALLVRVE--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JN8-1", "uniprot_id": "NEUL4_HUMAN", "id": "Q96JN8-1", "name": "Neuralized-like protein 4", "aln": "MAAGSGGSGGSGGGPGPGP--GGGGGPSGSGSGPGSNGGLGSGGELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQITVLPPEP----------------------GFSPPTPIPTPPLEPLAPTEDSALAEQGTSADEAFMVSPAQARPETFPNSLESHNDFANMELSEVVSNTILSAYN-------------------------------------------GGLLNVNLSSPPAGEGLGSSGAATSP-ILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDR---LRRN-------------------------NAILRALSPE---------GALRRAAPAAQAEP---ERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDD-VEVAPVPEPLPEGNNQVSPSSPSSGAGG---SDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNT--ATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAG----YAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLEESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVNPEPGAASGKS---------------AGTQGDMEKADMVDGIKES----VCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKR----------SLCYCESCRKLRGDEAHRRRGE------------------------------------------------PP---------------------------------------------------------------------------REYALPFGWCRFNLRVNPRLEAGTLTKKWHMAYHGSNVAAVRRVLDRGELG----------------------------------------------------------AGTASILSCRPLKGEPGVGFE-----------------------------------------EPGENCAPPREEQPPPVLLSPSLQYAGAETLASKVQFRDPKSQRTHQAQVAFQVCVRPGSYT-------------------------PGPPSAALGEPPDPHFSPA------ELEWVTKEKGATLLCALLVRVE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QMX5-1", "uniprot_id": "A0A8M9QMX5_DANRE", "id": "A0A8M9QMX5-1", "name": "Neuralized-like protein 4", "aln": "-----------------------------------------MAAELHPRSGKLIGLSNSNRTAQRNQPVQEFNHGLVLSREPLRDRDVFTVRIDKKVNSWSGSIEIGVTALDPAGLEFPSSATGLKGGSWIVSGCSVLKDGRSVLEEYGRDLDQLGEGDRVGIQRNGKGELHLWVNGQDCGAAASGLPSRLWAVVDLYGKCTQVTVVSCEPPSEMEGDEDEEVEDEIVSTQAVSIMADACRSHDDRAAVLTAAAATTERMNGSAEEVPEVSRTHSRPDKFPNNFEPDSVLTEHQLFDVFNNAIVSLYRSEDDGAEDLNVGGGGGGSDSSRGGTGSNGGGRGTGSDSGIGGGGGGGGSSSNSSPAGNAGGAAGLGVGTGGMTTNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRHNEMFEIRIDKLVDKWSGSIEIGVTTHNPNNLDYPATMTNLRSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLMRKASGALHFYINGIDQGVAANQTPGVVYGVVDLYGMAVKVTIVHNHNHSDR---LRRN-------------------------NAIMRALSPD---------VGRPRPALSLTPEPDIPDRLLFHPNCGQKAAIISDGRTALRPHATDDFNHGVVLSNRPLHSNEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRKEDGSLHFFVNGVPQGPAAWNVPPNVYAVVDLYGQAAQATIMDDMADLPPLPDDSSEGPTAMSPGSPCSISGATAANDLRFHQLHGTNAVITNGGRTALRQNCRSEFNDAIVISNRCLREGELFEIVIQKMVDRWSGSIEAGVTAIRPEELEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDSLTTASRIGMMRTATGDLHYFINGLDQGVACTGLPS--EVYAVVDLYGQCVQVSITSSSGPLDNSLCTSN---ITEKSFPIHSPVAGVAHRLHSKHGKNVVLLGDGCQALRVGG----YAHGIVFSAKELKTDEVFEVKINKVDERWSGSLHVGLTTLQPPDLPSCPLSG---LSPSLTQLRTKVTWVLAGSEVRRNGVLQRQNYGCSLDRLTVGNRVGVKRCSDDTMHILIDGEDMGPAATAVAKNVYAVLDLYGKVTAVSIVSSTLVEDSESVKAPSLSSDSCSEGEEDCTPVR---ECENEPPLVPTVMTFLENHGKNIQLSNQNLTAARVSSYNQGLLVTAQALPRQQLFQFQIDRLNPSWTSSLSLGVIGHSPDRLNFPSTACCLKRSVWLLQRDSVFHNSLKICENYGPNLDTCPEGTVLGLLVDSSGCLHLFVNGMDQGVAAQDIPSPCYALIDLYGQCEQVTIVANHVPVVGGERG-------------DMRCQGDMEKADMVDGIKES----VCWTPPPEVNPNKTCEYQALCSRFKDLLTLPDGYFNEDAKY----------NLCYCESCHKLRGDEAYYKRGE------------------------------------------------PP---------------------------------------------------------------------------RDYALPFGWCRFALQIKTHCEVSNAFKKWHIAYHGTSVGSLRRTLDHNQLLS---------------------------------------------------------AESSSIFSSSSVKTEGHGSYG-----------------------------------------EPEENSAPERD--IPRVQLSPTMRYSGLEVFAPKVQFRDPRSLRCHQAQVGFQVCVRPGSYK-------------------------VGPSSLGISEPLDPRFSNA------EIEWITKEKGGTLLYGLLIRVE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A1L4AAD6-1", "uniprot_id": "A0A1L4AAD6_DROME", "id": "A0A1L4AAD6-1", "name": "", "aln": "-------------------------------------MTGREAQSFHTRCGRSIRLYNNNRMAQR--SMRDFSHALVFSAEPLEDDVLFEVVIEKKNTYWGGSIEIGVTAESPDDLELVACATAMRNGTWVMSGIDVRKDGRRLFEFYGTDLETLNENDRVGVMRTSGNDLVFYVNGESQGVAAKNMPKPLWALVDLYGRCVQVSLCPRDG---------------------------------------------------SGSGELLDSPLQQPLQQVVQNLD-----VAMNVNIVVDSDAWMQGN-----------------------------------------------------------GSVSG---------ADDRLCFHTRCGSLVKLSPNFRSAERRRPLDEFNNGVVMTHRPLRDNELFEIRIDKLVDKWSGSIEVGVTTHNPAVLHFPATMTNMRSGTIMMSGCGILTNGKGTRRQYGEFNLDELREGDRVGMMRKANGNLHNYINGQDQGVAATRAPSTLWGVIDLYGMTIKVTIVDRDEREQQNLVTRRNNIVAGMTACSSGAGAQHTQHQQHSGTPTLSLLSPESEMNAAGAAGGLSETISSTRAIARNDDRLTFHHICGTHATVTQSGRTALRPNAADDFNNGVVLTRRPLRPNELFQVRLERVVTKWAGSVEMGVTTHSADELDFPFTMTNVRSGTWMMTGNGVMQNGVTVIEQYGQNLDRLQVGDRVGVVRKDDGTLHFWVNGVDQGPAANNVPERVYGVIDLYGQAAQASIVDTSECGSPDTGNSTISNTTLYSEVP-----------LRFHSIHGANAGISNSGLTASRPNSLAEFNDAIVFSNRPLRQRELFEVELETMVRHWSGNIEIGVTGTRPEDIQLAPNATDLEASDTIILCGPMIFHNRKTIRTNILLDLDTLGPSTRVGVMRNGD-FIHFFVDGMDQGPACECHAP--NIWAIIDLYGQCAQVSLTQTQLDIRAPYATSENSQSCQATSVIQHPAMETKHRWTCVSG-NVSLTKDWTEASRFTGAAAPLSHCLVFSEHPLSVGSPFEIKLTSVNSMFAGCLSIGVTDLNLSDE-----SVRKKLPTSIRRIPAN-VWYVSGNEVCFNSSCLQRSLAS-LEWLRVDDRITLER-VENSLNILLNSENVNIHFHNVPNDVYVVAELRGSTMGIQVISAQGPASPLRPCSLRLQDSMDFGVDPLNKQDSSMLESIDSEALN---YEFLDVSQKNARLSDDRRSVTRIKSYNQSIVCLNKPLCKGESISIKVDALNNKWKGTVGLGVLSASP--QTVPISLLDFKRSCWLATHDYVNINGQVMPSKYGDALEQIQVGTVITLTLTHAGMLIIMIGSTNLEDLASGLPNHVYPVFDVYGKCEKITLITGNDAGRTGNANGTPILEAPEALELDNGMPQQCEKAHLEMHEKEKDTEQVCESGPSTSGAPSNAMTRSVMESVSENLLLNISIKNRTLEQQRNELGGSSSTCCLRESLQLQHNTNLNIQRSQSTQRFQNSLNTSATAAGSSGTSGCTANTQHLSNSGVYDTNKEYDDLPNPPNPLVNSVDEASGAITSVSTTIDHSENNAEALELSASNEREMSGEPALNDNVLEDDEIDYMNHLLLLQQLQQNEYTRHHLMPDQASLLNLDLPSLNSMESDTNSVGQTRPSGGTDSLRSTATGASVEQNDCEYLRQVRRFCASLVLPQAFFDSRLEPVCFCLKCSGPSIGGNGDKLEGWVYFKLNQQTVNVLSTSTSTASAGGGASSATAPQVHFDLNGDWLPFYYMTRVDKIRAILDRGQPLPLETDPDEEPAAAALKDEPGTRLELYYSPNATVIEPVLPQHHFASEQGLHRISTSFEVYVRRQSISGVTTGKAAAEAKRRSLGSTDHDHGGTGQGADGVGVTPSATLNESSVHLLNDLCWFTKEAGACIINALIIKLDRIEESESH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:*.* *: : * .* *:* . ::*.*.**:* ***.* :* * *::* . *.********* .* *:: :.**.::.*:*::** .* :*** ::* ** **: * *.****: *. .:* ::***.. *.**..:* :**:*****:*.*::: . : * . * : : . :.:: . :: *... . . :* ::* * ** :**:*:*** * ::*****************:****.**:*****************:******* *.:******::********************:* **.****:***::*: **:.. ** :*** *****: :* .::**:*****::*****...::.:: *** .. : ***: . .. : . . :** ** ** :*:: .*******:*:****:****: *.*: .*:****::::* *****:*:*****.. *::* ****:*************:**.*::::**:*****:.** *****::**:***:***: ***** *** **.*:*********:*:* .* . . . . : . * ****.:**:** *:*.* ** * *. :*******:*** **: ****: ::.** :***.** ***. ***::::. . **:: ** :*.*. *::: :*:*.* ***:* ..:*:*:**.. :*:*::* *** ** .. :::*::******.***:*.: : . .**: : : :: *. . ** . * ** * * .* * * :* :*** : * . . **:*: .::. ::*.* :*:* * : . *..*: .: :: .* ::. ** :. : . . *: * *..*: :.* :::::**::.*::. :.::*:.* :* * . .: ::*: .. . ... : :. : **: ** **: . :.:*: ****.:: :.* ...::* ** .*..:: ***: .* ..* : :**: ** * *. : .::* *: **:: * : :* * : :.. : . .:*. :.:.*:**:**::*:: . *: : ***.: **. ** *. .. ... ::: . ..: * * . : . * ** : :. : :*.: ** *.: :* . : * : . . . :. : . .. :* . .: : .::* . . . . :* *: *. * . *. . . *.: . . *: ...*:* ** * . * : .: . :. : :: *.*** *. :: .*::::: ", "identical_positions": 519, "similar_positions": 468, "identity": "26.33%" }, { "cls_id": "homologset.agr.HGNC:34415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R218-1", "uniprot_id": "T150B_MOUSE", "id": "Q8R218-1", "name": "Modulator of macroautophagy TMEM150B", "aln": "------------------MWNYLSLLPVILFLWAIAG---IWIVFAIAVVNGSVDLNEG--FPFISICGSYAPQSCIFGQVLNIGAALTVWICIVRHHQLRDWGVKTWQN---------------------QLILWSGILCALGTSIVGNFQDKNQKPTHLAGA---FLAFILGNLYFWLQFFLS--WWVKGLPQPGPHWIKS--------------------------LRLSLCSLSTILIVAMIVLHALHM-----RSASAICEWVVAMLLFMLFGFFAVDFSI------------LRGCTLHLHPRLDSSLPQAPSGSPNIQMAQVL-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZEH7-1", "uniprot_id": "D3ZEH7_RAT", "id": "D3ZEH7-1", "name": "", "aln": "------------------MWNYLSLLPVILALWAIAG---IWIVFAIAVVNGSVDLEKG--FPFISNCGSYAPQSCIFGQILNTGAALAVWICIVRYHQLRDWGVKTWQN---------------------QLILWSGILCAVGTSIVGNFQEKNQKPTHLAGA---FLAFILGNLYFWLQFFLS--WWMKGLPQPGPHWIRL--------------------------LRLSLCSLSTILIVTMIVLHSLHM-----RSASAICEWTVAMLLFVLFGFFAVDFSS------------FRGCTLHLQPHLDSSLQQAPSGSPNIQMAMVL-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NC51-1", "uniprot_id": "T150B_HUMAN", "id": "A6NC51-1", "name": "Modulator of macroautophagy TMEM150B", "aln": "------------------MWGYLSLMPVFLAVWAISG---VWIVFAIAVTNRTVDLSKG--FPYISICGSFPPQSCIFSQVLNMGAALAAWICIVRYHQLRDWGVRRWPN---------------------QLILWTGLLCALGTSVVGNFQEKNQRPTHLAGA---FLAFILGNVYFWLQLLL---WRLKRLPQPGAAWIGP--------------------------LRLGLCSVCTILIVAMIVLHACSL-----RSVSAACEWVVAMLLFALFGLLAVDFSA------------LESCTLCVQPWPSLSPPPASPISLPVQL---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PK2-1", "uniprot_id": "T150B_DANRE", "id": "Q32PK2-1", "name": "Modulator of macroautophagy TMEM150B", "aln": "------------------MWAWA-LLPVFLAVFGTVG---LWAVYAIAVSNNSVNITIE--FPYISTCGAYTPQSCLFAQICNICCVLALWIVVIRFQQIRDLGRSSHLN---------------------TAGLVLGFISSIGISILGNFQQTIIQEVHLLGA---LMAFFLGLAYFWIQAFIT--YFSP--PSRDNKWLVP--------------------------VRFVLCSQCTCMVICMFVLHSTGF-----RSAAAICEWILVMCFFALFGVFAAEFRH------------IDFHKLTVQ-KEGLKVANNDNVVWTVQDVQ-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35735-1", "uniprot_id": "SFK1_YEAST", "id": "P35735-1", "name": "Protein SFK1", "aln": "MIQFKSPGNWLFIVPWIAFIPWYGMLIAMLICWASQGHPIYWFMHSEQFPVYISDIGATNLRPLFISCAGWQGLGYVITVALEFFQRSGYLPFQLKKKDPSISDSTSYAEKLHSGKYLMPPYYTKDERNLIFAAFVLGSIGELALLFSSIFSTALYHRVHIAMVSVFVVFMFLSTCCLIAEYFLMGRHYASVHPLASPHFNPQSSEKSFNQDYNTVDELPWYKWKGHVWNKFTISATLKVIWLTLAVVWAICFGAINDRSKSACFEWLLAFWFGIIFMILSADFYLGGRYRQSRYFNHVESFSGYYKYDKALGLYHSEDVLPSDDNAGVIATETASSNIYNNSSSNESIQVVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: .:* :. * * :.: . :: * : *..: . :: : :: :: . : : * : :. . . *. : .*: . .: ::*. : : :: * . : :: :.: . : : : *: : : ** :* ** :.: : :* .::.:* . . : : ", "identical_positions": 18, "similar_positions": 77, "identity": "5.1%" }, { "cls_id": "homologset.agr.HGNC:34416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBU5-1", "uniprot_id": "SBK2_RAT", "id": "B1WBU5-1", "name": "Serine/threonine-protein kinase SBK2", "aln": "-------------------------------------MPGKQSEDRPMEVAAVEDGGDEGLGGLTVEELQ--QGQEAALALEDMMALSAQTLVRTEVEELYEEVRPLGQGRFGRVLLVTHRQKGTPLALKQLPKHSTSLRSFLYEFCVGLSLGTHPAIVAAYGIGIESANSYSFLTEPVLHGDLITFIKPKVGLPQPAVQRCAAQLASALEHIHSHGLVYRDLKPENVLVCDPACQRVKLTDFGHTRPRGTMLRLTGPPIPYTAPELCAPPPLPEGLPIQPALDAWALGVLIFCLLTGYFPWDQPLVEVDPFFEDFLIWQASGQPQ---DRPQPWYNLSPAADTLLWGLLDPHPRKRNPVSSIKSYLGQPWKQR----EEGAEELTKELREDGSRGGQEAAKG-----EQPAC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C5K1-1", "uniprot_id": "SBK2_MOUSE", "id": "P0C5K1-1", "name": "Serine/threonine-protein kinase SBK2", "aln": "-------------------------------------MPGKQSEDKPMEVSTVEDGGDEGLGGLTVEELQ--QGQEAALALEDMMALSAQTLVQTEVEELYEEVRPLGQGRFGRVLLVTHRQKGTPLALKQLPKQSTSLRGFLYEFCVGLSLGTHSAIVTAYGIGIESANSYSFLTEPVLHGDLITFIQPKVGLPQPAAQRCAAQLASALEHIHSHGLVYRDLKPENVLVCDPACQRVKLTDFGHTRPRGTLLRLTGPPIPYTAPELCAPPPLPEGLPIQPSLDAWALGVLIFCLLTGYFPWDQPLVEVDPFFEDFLIWQASGQPQ---DRPQPWYSLSPAADTLLWGLLDPHPRKRNPVGSIKSYLGQPWKQR----EGEAEELATELREDGWRGGQEAAKG-----EQPAC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C263-1", "uniprot_id": "SBK2_HUMAN", "id": "P0C263-1", "name": "Serine/threonine-protein kinase SBK2", "aln": "-------------------------------------MPGKQSEEGPAEAGASEDSEEEGLGGLTLEELQ--QGQEAARALEDMMTLSAQTLVRAEVDELYEEVRPLGQGCYGRVLLVTHRQKGTPLALKQLPKPRTSLRGFLYEFCVGLSLGAHSAIVTAYGIGIESAHSYSFLTEPVLHGDLMAFIQPKVGLPQPAVHRCAAQLASALEYIHARGLVYRDLKPENVLVCDPACRRFKLTDFGHTRPRGTLLRLAGPPIPYTAPELCAPPPLPEGLPIQPALDAWALGVLLFCLLTGYFPWDRPLAEADPFYEDFLIWQASGQPR---DRPQPWFGLAAAADALLRGLLDPHPRRRSAVIAIREHLGRPWRQR----EGEAEAVGAVEEEAGQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAH6-1", "uniprot_id": "A1ZAH6_DROME", "id": "A1ZAH6-1", "name": "Protein kinase domain-containing protein", "aln": "---------------------------------------------------------------------------MSKKPRGNIHKIREFELEKIQLVDEFDIIQIVGEGWFGKILLVEHRGSQTEMVLKAVPKPYVTLRDFYREFHYGLHLGVHRHIVTTYDVAFETAGFYVFTQEYAPLGDLTSNVT-DSGVGEVYSKRVAKQLASAIDYMHSKDIVHRDIKLDNVLIYRSDFQRIKLCDFGESFPTGSTVERRNEWLPYSPPEVLEIKPEGS-YKADPSHDVWQFGIVIFVCLTGCLPWQK-AASDDPRYVRYLAWQGGLMMMPLRRTPRLFKLLTSNAQRMFKRFFARISNRPKSLADVTKFLDDRWLAK----TAQKEMAEYETDELCPSMYSFHSSP-----DEKNKLLYTLADCGIETNVDRQQKKNRIKDWIESSIITEEDEEENEETNSASPSSSVSREPLPGHISSLRKPTSPAESAKEINSTLKDATQKHFDPRTGALQQGPSEMGQVAMAYSKSASPASNYSTTASTLNNADSLMTLGSRQDLLASNLTMYTSMETELNRLGEADPRLNQRTQSNNPLLTTFDVNTNPAAKNSIGVGTRGSSRSILKSSIATAAYPALGAFNHGQSHSLQQLNQHLQTSTGLTPSKSSFFRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM90-1", "uniprot_id": "SBKH_DROME", "id": "Q9VM90-1", "name": "Serine/threonine-protein kinase meng-po", "aln": "MGTIEKRSFSFRLRRSFGDGGSTNSRNSNNNSSTCTNHNNQKRCSTPLTPTSTSTGRLEVPGAASVSRRSSIYKKPDKNDGGQIHLIPDVELPLMTFADQYNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYELSHHHHILSAYAVAFQTMDYYVFAMEHAPYGDLASNIG-PNGLHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKLCDFGATTKKGLLVHKVKHTWTSCVPPEQLELIKNERFQCLPVSDSWQFGILLYNILTGNPPWQSADWVKDQSYANFMKYEQRKTTK----VPDNFRRFSPRLMRCFRKYLSHDPEDRCKITEVAKYMKDRWVECRISTSKSATLISPTNHDQDSCIYLNQREGRLSGDENKLRFKRMMSTYGLDIPIDQAMVRRRVWDWLSTCDANFDPDVESLHALDLLQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * . : :: : :.:* :.::** ** . * :.** : .::: * ** . *. * *:::* :.::: * * * . *** : : *: : : : **:**: .:*::.:*:**:* :*:*: . *.** *** : * :. . * . * * * :*:::: *** **: * : :: :: * : ::. : : .. : : ..: * : ", "identical_positions": 54, "similar_positions": 85, "identity": "8.13%" }, { "cls_id": "homologset.agr.HGNC:34417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7M4-1", "uniprot_id": "M0R7M4_RAT", "id": "M0R7M4-1", "name": "", "aln": "MSLSRP-AWPSGPAWPLSSEPPPQDPAAASPSSKRRRLKEPDG-VCEAGWPLLVVPRLSEVEKVWEWSPRPFTAFLIPK----------SPGSSGGGRQRCDPGCGDTTFQTQNCWQSGISGRAVCSRAPGRSCEAGLKDG--EGVYLG--DQAEVSHAPPNTLMPHVQGVKQESEELPEKETILKEKNSVARQPRNPFLDVTFSEETKSALHEIKDRCKVDSVITSEKREN-VSSSTLKIPKIQNQACLESAKPSYFRDSITKNFPEFPRDLNSNMSFVYLKEVAKKKNDKIVAYVRDFTNIFLSQNRPDAKKQKLQD-KKYVHVENDFSDYSESNHQSLTIEG---KIDLINLNYYRHGSIECDVRDSKKNITLTLENANLEGAERNQDYYIPTRQKESQSPNYN-KSILKRKQQN-WRMKKFRIIYENMNKHGEHL--NLALCGDLLHKADYHSVKVRNVMIGT--------LGSPPNLIKVVWFNGKGENINMLQLRYYTLQKYISGN---------------------KEDSTLICHEMSTCEKQI--------------DTQKSGVLSKYLQNSISEFLNMILKTNTVSLLDNFDSFIRN----AGDGESEEGCIFKYIVNLNYLKNIIQERHIVYLTKMLTSSRLLEHNTKSTVKKRKLFKMEHVLEWAKKQNINSLTMTTK--KFPVYKVCENVPLLMNFDSTEELSLTKQPSYENTNCAEQLLNMGDLAYYMFGISNSHVKSDLLFIQNNCGHINEKYYESSMCSQDLDTERKWKHKAIH-LIFKFIFEDVFNVRQLCMLLSQNTSHSDQINAMAITLKINLEDLLSKIEGKIYDFVLKKEMKVTKS--SSSCQVHKAIDTKKQE-SSFLPMDRMSSVQSASLVSKSINMEETKSVNQNNGTSAKEDGGILQEIELTNSKHFHPENESALYANHQFESDSSGENNECFQGLTAKCLSTETLPIANEFEIKSKFDLVLEELRMFHEISKENEIPSTMETHNREENYFGESNDVKEARMEIGNKLEMVETSTRDTSLLPCDVKAGLNKHKRHQSLFNWKVIPTHGGQAVPNESCP--GSEEELFHSTPEEDYKKPLPKSSTFSPDEYKKET--LLKGGSHVSHGISRVQPLKTCSRPIRVGLSRRARLKQLHPYLK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UW63-1", "uniprot_id": "G3UW63_MOUSE", "id": "G3UW63-1", "name": "", "aln": "MSLSRP-AWPAGPAWPVSSEPPPEDPAAASPSSKRRRLKEPDGGVSEAGWPLLVVPRLSEVEKVWEWSLRPFTAFLIPK----------SPGSSAGGKQSCDLGCRDRTFQAHSCWQSGILG---CSRAPRRSCEAGLQDREVQGVRLG--DQAEVSHAPPNSPMPYVQGVKQEPEELPEKETILKEKNSVR-EPGNPFLDVPFSEETKSALHEIKDRCKVDSVITSEKKEN-VSSSTLKISKFQNQACLESAKPSYFRDSNTKNFFEFPRDLNSNMSFVYLKETAKKKNDKIVAYVRDFTNIFSSQNRPNAKKQKLQDDKKNVYVENDFSDYSESYHQSLTIEG---KIDLINLNYYRHSSIECDVRDSKKNFTLTLEVANCEGTERNQEYYIPTRQ-EFQNLDCD-RSILKIKKENCWRIKKIRIICEN----------------------------------------------------------------------------------------------------------------------------------------------------------NMILENNIVSLHDNFDSFIRKKEKKKDDRESEEGCIFKYIVNLNYLKNIKKERYIVYLTKMLTSLRLLECNTKSTAKKRKLFKTEHVLQRVKKQNINSLTMTTK--IFLIYKLCENVPPLMGFDNTEELSLTKESSYESTRCAKLLLNMKNLDYYSFGIDGTHVESDPLFIQNNCGHINEKYYESSMYNQDLDTVRKWKHKTIH-FIFKSIFEDVFNVRQLCTLLSQNTSHSDQINAMAITLKISLENLLSETEGKIYDFVLKREMKVTKS--SSSFQAHNAIDTEKEE-DSFPTMDGMSSVQSASLVSKSINMEETKSLNQNNRTSTKEDGGILQESELANSKHFHPKNESALYANHQFESDSSGENNECFQGLTATCLSTETLPIAEEFEMKSKFDLVLEELRMFHEISKENEIPSTRMTNNRKENYFGESNDVKEARMEIGKKLEMVETNTRNAPFLSCDVKAGLNKHKRHQSLFNWKMLPTHGGQAVPNECWP--RSEERSLHSTPEEDYKKHLPKSPTFSPDEYKNET--LLKGGSHFSHGISRVQPLKTCSRPIRVGLSRRARLKQLHPYLK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09MP3-1", "uniprot_id": "R51A2_HUMAN", "id": "Q09MP3-1", "name": "RAD51-associated protein 2", "aln": "MSLPQPTPRMAELRKPTSSLTPPEDPDSQPPSSKRLCLEEPGG-VFKAGWRLPLVPRLSEAEKVWELSPRPFKGLLVSTNAIFDNSTDSCVEKSVSGKQICNLKCSNLKFQMSSCLQSPPSQSPDSDLRASGRSEAGLHDREAFSVHRSNSSKAGVSQLLPSTSIHDIHGIRNENR----KQQFVQGRDNVH--KENPFLDVTFYKETKSPFHEIKNRCKANSVVPSNKRENNISSSVLKISKSQNQPSLEIAKPSYFRDSGTISVPQFPMDLNSKMSSVYLKEIAKKKNDKKEAYVRDFTNIYWSQNRPDVKKQKLQNDKKTVEAENIFSKCYENDYPSLSSQNTCKRKDLISSNYCNCSSIQCNVRDSRKNFAI-LENANWEEAEC-LDSYVLTRLEKSQNWDCNVRHILRRNRGNCWIINNCKTKCENMKKTEEKWNWLLLLEIDLLSKEDYHCAKVINAYEEQSKLLVREILGSQTALITTVWLNGKGENDNTLQLRYNTTQKVFHVNNPFESFIIEIFYFHKSISGNKKDNSILTCCNILKCKKQIGIIGIQNLITRNMNTNIKNGILSIYLQDSVSEPLDILLKTNIAFLLNNFDSLTRI----ENDFELEEECIFKCMLYLKYPKNIVEN-HTAYLVKILTSSRLLEDNMKPMLKKRKLFRTEQVFEKSKKKLINSFSMTTQNTGFPIFETYEKIPLLMDFDDMDEISLIREITCQNMSCPQQVVNVENWAHYNSSTVKAHGNSCPQFIQNNRGYINENFYEVNMHSQDLNMERKQGHNKISNFDCEHIFEDLCNVRQQAIPASHNIIHNEETHTTSITQVLNFWNLLSEIEEKKYDLILKEEVKVTAESLTNSCQVHKDTKIEKEEKDSFFPMDDMFSVQSVSLISKEVNVEENKYVNQNYVTNTNEYESILPEREIANSKDFHRKNDSALYINHQFETGLSEGNDECFQDLAAKYLSTEALTIVKDFEMKRKFDLVLEELRMFHEISRENELLSTVETNNGQENYFGE-NDAEKVKMEIEKDLKMVVVNKIRASSSFHDTIAGPNMGKSHQSLFKWKTVPNNGEQEVPNESCYPSRSEEELLYSTSEKDCETPLPKRPAFLPDECKEEFNYLLRGGSHFPHGISRVRPLKTCSRPIRIGLSRKARIKQLHPYLKQMCYGNLKENF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.:* . : * ** .**:** : .***** *:**.* * :*** * :******.***** * ***..:*:.. . .* .*:* *: * : .** .* ** .. . .****:* .* . .:* **: *.: : ::*:::* . *: ::: ::.* ******.* :****.:****:***.:**:.*:*:** :***.***.* ***..** ********* * .. :** ****:** ***** ******* *********: *****:.******: ** * .** **. *. : **: :. : ***. ** . .**:*:****:**::: ** ** * :* : *: ** : *. : : : **: :: * * ::: : ** :::*:.* . * :****: * .* * ** **** :: *:* *** :: : .**.*:*** **** * *. ******: *:*:: **: ***::***: * ::: *::* **.**. :*:** :: : :. *.: ::*: : :* . :* :* ***** *:***::** .* .***: ** *: * : : ****: **** . *:* *.:: :: :** :.: :***: * * **::**.*:*** . :.* *.*: . :*:* .** .** * ****.**:**.:*:**.* :*** *.::* .** * *::***.** :*:**** *****:. * *:****.*:*. ****:*.*.::**:* ****************:***: ** *:* :****** **.::.:*** :.*:** ... :. *. ** * * *****:** :*.:* * ****. ***. ::**.*:* :. *** .:* *** *:* **:****..******:**********:****:**:******** ", "identical_positions": 471, "similar_positions": 265, "identity": "40.12%" }, { "cls_id": "homologset.agr.HGNC:34418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIN5-1", "uniprot_id": "F228A_RAT", "id": "Q5XIN5-1", "name": "Protein FAM228A", "aln": "MADTKSSNCNEHFSVEKLKEWPEPESVSLMKELAREDIDEAVHAILFRENYIVKKLDTYLQHEAVFKERRKEMLHKKWVENVAQPLQQRIIEKLFSYRRPGKSQVKYEYCLKHTNEPTKPSPLCECLFQKQQALREAKGPSYHRGRGKQPGIQKEAKETEKGLLFTRSPQFPLRSHCTVPRDRQRLHARFVQNKPCGRNKYKGAGSEKVSYALKPHLPKEEKKTVNRSQLGFERQFHASKLSQQNKGAEKKGLALGTRAQRPRSWAAADSPQGTPLVGRRVMTAEILGKHLASLQQASRAVYSNSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDW1-1", "uniprot_id": "F228A_MOUSE", "id": "Q8CDW1-1", "name": "Protein FAM228A", "aln": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVS--SSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTP---FSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEK-TVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W67-1", "uniprot_id": "F228A_HUMAN", "id": "Q86W67-1", "name": "Protein FAM228A", "aln": "MAATKTASYDEHFRPEKLREWPEPESVSLMEVLAREDIDEAVCAILFKENSIVK-------------------------------------VTVPPFVDP--------------------------LFQRQQEVDEERRTGLQCETGKRH-SIKELEEIEKARLHASSPYFTFTSHCVIPKEWHKASAR-------ARSKTYKYSPEKLIYADKKQKRKEKK-TADLSQAAFERQFLSSKLSQKNKVGERKGLVS---RGLGRGWHAG----------------------LCSTHEQHILVPE---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **::. :*** ***:***********: ********** *:**:** :** .: .: * ***:** . * : .. : ** ** :* **. .: *.: .** *:: :: ** .*.: ..** :: * : **:* *.. ** ***** :*:***. * .*:***. *.* *. * * :: . ", "identical_positions": 87, "similar_positions": 52, "identity": "28.43%" }, { "cls_id": "homologset.agr.HGNC:34423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJZ0-1", "uniprot_id": "CAST1_RAT", "id": "Q5BJZ0-1", "name": "Cytosolic arginine sensor for mTORC1 subunit 1", "aln": "MELHILEHRVRVLSLARPGLWLYTHPLIKLLFLPSRSRCKFFSLTETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVMNVS---HSGSVVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAREFQIYREVGGEPVPVTGDDSSNGFPQ-AQHGPSPTVHPIQSPQNRFCVLTLDPETLPAVATTLIDVLFYSHSVPKEAASGGPESTSIPFFAFSLIEGYISIVMDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAVDVSAYYISTFNFDHALVPEDEISCVIDILQRRQEGLASKDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWQ8-1", "uniprot_id": "CAST1_MOUSE", "id": "Q9CWQ8-1", "name": "Cytosolic arginine sensor for mTORC1 subunit 1", "aln": "MELHILEHRVRVLSIARPGLWLYTHPLIKLLFLPCRSRCKFFSLTETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVMNVS---HSGSVVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAQEFQIYREVGGEPVPVTGDDSSNGFPQ-IQHGPSPTVHPIQSPQNRFCVLTLDPETLPAVATTLIDVLFYSHSVPKEAASGGPESTSIPFFAFSLIEGYISIVMDAEIQRKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAVDISAYYISTFNFDHALVPEDEIGCVIDILQRRQESQASKDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WTX7-1", "uniprot_id": "CAST1_HUMAN", "id": "Q8WTX7-1", "name": "Cytosolic arginine sensor for mTORC1 subunit 1", "aln": "MELHILEHRVRVLSVARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVLNVSS--HSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAQEFDIYREVGGEPVPVTRDDSSNGFPR-TQHGPSPTVHPIQSPQNRFCVLTLDPETLPAIATTLIDVLFYSHSTPKEAASSSPEPSSITFFAFSLIEGYISIVMDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYISTFNFDHALVPEDGIGSVIEVLQRRQEGLAS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6H9-1", "uniprot_id": "A0A8M1N6H9_DANRE", "id": "A0A8M1N6H9-1", "name": "Cytosolic arginine sensor for mTORC1 subunit 1", "aln": "MDLHILDHRLRVTCISKSGLQHYTHPLIKLIFLRNRTRCKFFSLTETPENYTVVLDEEGFKELHPSEHLQVEGSTWLPLNVVSNGNASSSSQAVGVTKIAKSVIAPLAEQHVSVFMLSTYQTDFILVREKDLSVVVETLVEEFNIFREEGGESVPVHSQDSCNGLQRNGREVPHATVHPVLIPENHFCVMSLDPDTLPAIATTLIDVLFYSNS-PKEGASVDQDMECIKFFSFSLIDGYVSLVMDTDAQRQFPADLLFTSSSGELWRMVRIGGQPLGFDECGIVAQISQPLADSDISAYYISTFSFDHALVPEEDITSVMEMLQTQRKEMSS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:****:**:** .:::.** ********:** *:************:**:::******** ***.*** :*** :** ::.: **.******:********:****:**************:*****:.**..**:*:** ***.*** :**.**: : :. * .****: *:*:***::***:****:***********:* ***.** . : .* **:****:**:*:***:: *::**:***:*****************************: *** *:********.********: * .*:::** ::: :* ", "identical_positions": 218, "similar_positions": 74, "identity": "65.07%" }, { "cls_id": "homologset.agr.HGNC:34427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDY6-1", "uniprot_id": "M0RDY6_RAT", "id": "M0RDY6-1", "name": "", "aln": "MSGGRRRGSAPWHSFSRFFAPRNPSRDKEEEEEEKPGTGQPAGANRSAASAENESMSTSQKKENAPSSEAVKIPQVEDRRNPAEQPAILPMVDDPLKPKDLPDSTVDAKTGESDRQPKESFFQFLGNLFNISGKSSLGEVKQSSFKDDQDKPEKDPQTPTGPPEEGSQREKEITSCPVRTRILPEDQRESNSSELSDAFSLDTTQESEQETTDTLKTDTAGKPEKPSVTYATYRGPTQIRKYLKKQPGSETVNHLNREDGNSDSSTQARTGSRS-IPDTVTVPLSTASKDVTTKGHLLGGPLEVSGYSQTNTNIENDLESPPELQKIASSKYILNKNSLGDPSSSWASPSSVSNPSY---------VVGEPDSQMERSLVCSSVFRGSKSSQGPC-PEFQRKTATENTLRVNSSAVSDGLPSVPAEERVQPQRPAVSDFSCSKSDGSDTTKMESTNLSSPNKSIRHEDVRLPESKCCDKPAVDNPSRQDVNHTRVTTLRGHAVTDSGLVNEGKKLPAQDKQKNVLS-EVLRETECASGSEPTTYSHVRAPEVRIESLPKETELPCDTETEKLGVEPHVQTPPQEMGETQEDPGSVKSVSDSVGIACTESETAHELKSESNRNPISDSPCLLEPLQQGEVFSEAETPLNLDCKTSDCSASPPTSASRTDRLGQLGFPGLKGERSTS-SRTGQGNVC---SHPNECR-EAVGAHSVAADRENPRAPRQLRQASAIVDSKDILRDGEKCQFPSGPETPGTHSAGLGLLNFEPGDLSENLNSVPSHSPKKAALVSSSAKASRSPVEKSDSLPLETQTAKMLGNLEVCDQSSFLVELSSGRGKTLSVPPV--SQAEPRDVSQCDISSSQGTAAEKLSETVLSELNYLGMEKDKDAQPVDHRESKELCCSGGFKENHQTGIPPAS-KHQSVQETEINTLGTTASILRSRLPGIN-LAPEEESTRHMAQNCKASTSLLSPSFAVCGTKKSSSISEMEELRLDNISPKFQETDNTQVYTSFLGSDGRLEKNVLAPEVSSSLNVPSLPGLEGEDSSH--GDNSYFQSAGTGSTSP-SCHSKGDSTDVNSHDLPSNFESLKVNVNLTGEGASVTDPLGHNSFYLALDIPNPKETDMTSIQGGLGTHTRKASLDSPTTAYFDNPMKAETGTVAGAPVSVNRSCQQCSEASADQTEARRRAHDPLL-LRSSLLAKADTLTEEILSSIREELKSKHTVGSCQEHLAQDDIMNPGTVKEAI----PSEVVLAGIQLKESLDEKGVDNMSEVKEEEQTSVSSVVSETSLLFDLDRVHSSYLLEEQAKELVNEVTYAVQENLLNDAFDEIENTWVSEPQADPSNIWNSNGGDEPHALVREFLVAEQTVNQSTCEISENEVLSKFSSVSHLLSGTESVKGREIVPYQESPGFGSGAGQSVSRKLQRSETVVQAEGMPPTSLEGKVRPRLFVSEDYRKAAETECVDNHKMATEETRTLVLNFNLP-LANDDIHAPGTSKSSFSDSLVCISEKSLPWHNKSMPLVMSDLGKAYKIDNEVNVGKMVALPSMLETGKTNKRDAELNIRKHEAAPLMPHREKTCKMDAELNIMKAEPEVNMFTRGGVYQMDAQMHVEKPEDLPVTLGMEKAYKM-DSEGDIGKADVMPVMSELKALHLKDAEGDIAKTEVAPISIEMESFYQKHAEGDVGKTGVASVMSDVDIFYQKDVVGISPKAEVTTVTLGMEDTYQKEEESDVAKTDVTGMVPAELEMEDTYPKGSEGDTDSTEGKPIRLEVINIYQKYSDRVTGKMG-----RPMSPLRDAEDVLGNSETVPFVLDVKETYQETVHSPLDILEKRVQRDTEETN-GTEPVPSEINMEVMAPEDSSGSI-KNPEVGTEVAIESTNRTTPEVTITRMEAMGPVYESEMGPQEYMEKSIGELEELSSEVKEGLILHGDRLASHFRGYESPTLSRDYEGYPALAMPDFQEEDTVVRLNKIMSVPAVDDKRRDMDYRGEKEESDLAFVSQDEQDSSSFTILYEEPLQEEDKKISAEVRGTRSLLFPDTSSSGMPGLACERSESRTDLVHHFEKEGKLAEAFDGDNSEMFLSVEAKRYKIYPLALSPIYEDDSSQEDVLSNEVSPGHHGSTKSRESANQPSSVLSLLQSVSERLQRNFDGDDGDDRQVAEEEEEEAAVAAASGKGLRTERRERVTFHLPDPSITFYPDDDQESAGISK-SYVEFSEPTTSSLQHSLWPEKVPFLQKSDLTSKLHSSLKSAYHQYLQTSRTHSSETGTRFGGTLQEPVSKHFRVQDHAGRLSAYMENVDRLTLRCNPRPGKMIIYDLHGSKYKQEVYCNIPDATAWSFPNGALIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWLLQNRKHPERTFVLGSIKRVLKDCSIPEIELRPKSDPGWCPIYIHRSIPNLEELNIPKSSTFTVKSGVWLAYPDVNFKGQATVLEEDQGLFEISAAEMKSLQTLQMGGLKVEMPMNLKVIIYEKPHFRGHAKEFSEHIESVPKFLKSDKDFRGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSSACGALSGPIMSFRYLQANFIESSITLFES-DLESGKFIDITNQEISDLEEIGFGRETRSIHVKSGAWVAYHQKFFCGDQYILEKGKYKCFFDWGGSSNIILSIRPIQLEPLGINEPPHLLKAFSKAGFQGECIDFIKECADLTSFTPASFKVLRGCWLL-YYQEDGFYHQCVLEEGLYTDLTSCGCPSARVRALKPIDYFFEEPSISLFALEHCEGRELHLEDAVNSVLNKDLHFYTQSVWIKSGLWIAYEGSNFLGRQILLVPNEIPNWTAFSGWKTIGSVRPMRQPAVYIRIRNRAQDEYLTVTGNPADARTMSVCVSPYSGKDTQIWHYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRMNRNGTISSYLSDELVLDVKGGNYCDKTHVIVNQPLEGEETQKWDIEIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W49-1", "uniprot_id": "CRBG3_MOUSE", "id": "Q80W49-1", "name": "Beta/gamma crystallin domain-containing protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPVVYDKRRNLDCREEKEESNLAFVSQDEQDSSSFTILYEEPLQEEDRYTSAELRGSQSLLFPDTSS--MPGLACERSESRTDLVHHFEKEGKLGEAFDGDNSEMFLSVEAKRYKIYPLALSPIYEDDSSQEDVLSSEVSPGHHGSSKSRESANQPSSVLSLLQSVSERLQRNFDGDD---RQEAEEEEEE---AVASGKDWRTEKREHVTFHLPDPSIPFYPEDNQEHAGIFK-SYVEFSEPTTSSLQHGRWSEKELFLQKSDMTSKLHSSLKSAYHQYLQTSRTHSSETGTRFGGTLQEPVSKYFRVQDHAGRLSPYVENVDKQTLKCNPRPGKMIIYDLHGSKYKQEVYCNIPDATTWSFPNGALIKVVRGCWILYEKPHFQGQKCVLEEGERVLDRDWLLQNRKHPERNFVLGSIKRVLKDCSIPVIELCPKTDPGCSPIYIHRSVPNVEELNIPKSTSVTVKSGVWLAYPDIHFKGQATILEEDQGLFEISAAEMKSLHPLQMGGLKVEMPMNLKVILYEKPHFLGHTKEFSEHIDSVPTFLKSDKDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSSACGALSGPIMSFRYLQANFIESSITLFESSHLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYHQKFFCGDQYILEKGKYKCFFDWGGSSNTILSIRPIQLEPLGINEPTHLLKAFSKAGFQGECIDFVKECADLTSFTPASFKVLRGCWLLLYYQEDGFYHQCVLEEGLYVDLTSCGCPSARIRALQPIDYVFEEPSISLFALEHCEGRELHLEDAVNSVLNKDLHFYTQSVWIKSGLWIAYEGSNFLGRQILLTPKEIPNWTAFSGWKTIGSVRPMKQPAVYIRIRNRAQDEYLTVTGNPADARTMSVCISPYSGKDTQIWHYCRGLFKSKASHTCLDVIGGRDTPGAKVALWTEHGQLRQKWRMSRNGTISSYLSDELVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68DQ2-3", "uniprot_id": "CRBG3_HUMAN", "id": "Q68DQ2-3", "name": "Very large A-kinase anchor protein", "aln": "MSSGRRRGSAPWHSFSRFFAPRSPSRDKEEEEEERPGTSPPPAPGRSAASVENEPMSTSQKKENVLSSEAVKIRQSEDKRNHAEKPVTLPVQEDPKKAYDLSSSTSDTKIGESDRQPKESFFQFLGNLFNISGKSSLGEAKQSSFKDDQDKTEKDLQNPSDHHEDGIKREREIFSGSLRTQTHPTEEQDSNSSELSDAFSLDTTQDSDQETTNLLK-QIDGKPEKPSVTYATYRGPRHIGKYLKQQTGLATVNTLDRENESSDSSTNRHIDPGSEIEAGVLPLLLSASTDSSMKGNLLEGPLEDSDCSKTSFNKENSLTNNPELQNIASSNNLLNKNAWGSIERNRSSPSSVTNSSYDGESDSQHHLSCEPVSQTNRNLVCSALLTGSNHRKVPCSPDFQRVTTTENTIKENSTVMSN-RTLVQREELVEPQGPAISDFSCSKSDGSDTTEQESTNLPSPNKSIRHEHLQLPESECSDKQTIDSSSKQAATHTNIIALQRHAVTDTEFVNEGKRLSAQDSQKNVAVREIRRETESASAGESIASSHVKAPEDKIESLPKDTDQYFETKAKKLDFRSHDKIPHIRMNK--KDLASLNYISESAVVASLGNENAPELKFELNRSHISETPLDSESPQQAEVSPDAKTSLSLDCKKLNFSISPPTFVSGVGMLSKLDIPDLMNEGSPVPIETGNVNIVGISYQPRKCKEENVKNHVEAAGRKSPPPSFCLEYTSAIFEFKEVLSNSEKCQVLPGSEASGPHLTGLELLSFDSGNLSKDCSSILSQDPNRVELVSSNTKANMSIIEKSDSLSLEAKTANIVSKAEIDGQNNVLVESHSGRGKTISLSKVSLSKVEPRNISQDKMSSFPLKITHVPEKPILSELTFLEVEQGKRFQSINHNEIGEKCSDAGLKENCQAELSPAASKYEDKPEPEVDALGSPPALLKSNISWILPPIHDEKISRQMAQNCEAHTCVFHQSLDICGTKKISGHSEMAELSLTNISPKFQETGSMKVNSPFLDSDSSLEKNSSASEDSSFLKVPSVLKLEKKSSSYRKKENIHFLNGGIDSVSSSSSYPEEVSMIVNSHKPQNNLDSIQVTKDLTHEGTSVTNLLYPTTSYLEFETSVSIGTEVTPFQEHFGIYTGKISIDFPTAAQFDNLVEAETGAVAGPAASVNSSGQQCSEASAEHIEARRRAHDQLLDLKSSLLKKADTLIGEIFNSVREELKFKHTVSTCQEHIAIEGIMNLGTLKEDISEKNPSEVTLTEIQQTEGLEEQGMENMSEVKE--KPCVSPTVGEKNLLVDPNSMNVSCLLEDKARELVNEIIYVAQEKLRNDTFEDTEDTWDSELQANTSKILNSDS-VKPHDVVREFLVSEQPVNQST-QISENKVLNEFFSLSNLASGTESIKGGEIVLYQKSLFSGNGSGLSDSINLQESDTVLLAEDMSHKRLDDRVKTHLFRSEDCNETMEIENVDNNKTETEDRRTLVLNFKWPPLVNDDIHAPGTSKSSLSDSLVCISEKNLPGHSKNTPLAMSDVGKVHKKDNEINIGKIELIPSMLETGKTNKKDAELNILKYEAVPPMIEMGRIHKMDAELNVTKTEPKANVFKMGEVYQMDAESCIEKTEGSAVILGMEKAYKMKDTEGDIGKIEVIPMMPEVKNIHQKDAEGDIVKTEMTPVTVDMENIYQTHAEGDIGKTG-TIALSEVENIHQKGGEGISEKAEVIPVTLAMENTYQKDAEGDIGKAEV---MPVRLEMENTYPKDTERDGGKTEVMPLALEVVNTYQKNAKGFTGNTEGSVLKMEATYRKTAEEVIKNTEIVPCVLKVKEAH-ETAPAPLEM-EKACKRDVKETIGATVSTPSVIEMEKISPEDRGENIGKHKVLPAVVDIEKIHGTGLELTTKQGEAMLPAFESKT-PQEYAEGSVEETKEEPTEIKEGLIAHENRLPTYFRGYESPTLSKDYEGYPAPAMPDFQPGDTTVRLDKRMSLTAIYDKRRETDYS--DKGYNLAFVSQDEQENSSFTILYEEPLQEEDKYASAEARQTQSVLFHDTSADSMPVLACERSESRTDLVHHFEKGTKLGETFDSDSSEMFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGHHGPRKSRDSENQSSSVLSLLQSVSERLKMNFDEDD---REAADEEEEEEEAAVLHKGDLRAGSGERVTFQLPDPSITFYP-DDQESVGISKNSYVMPNEPTTSNLQVGLWPEKTSFLQKSDLTSKLHSSLKSAYHQYLQTSQSHSSEKGARFGGIFQEPVSKYFRVQDSPGRLSPFIENVDKQTLRCNPRPGKMVIYDLHESTYKQEVYCNIPDATSWSFPNGVLIKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSIPEIELFPQSDPACCPVYIQRAVPNLEELNISKSVSFTVKSGVWLAYPDINFKGQATVLEEDHGLFEISTAEMKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNACGALSSPILSFRYLQANFIESSVTLFES-DLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEETSDLTSLMPCSFKVLRGCWLL-YYQEDMFVNHCVLEEGLYADLTSCGCPASKVKSLKPIDYVFEEPSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLRPNEIPNWTAFSRWKTIGSLRPMKQPAVYIRIKNRAQGEYLTVTGSLADTRATSVCISPYSGKNTQIWYYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRLNKNGTISSYLSDQLVLDVKGGNYCDKTHVIVNQPLEGEETQKWDIEIL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:..: ****: * .: :*********:.***************: *** * ::*:** ***: ** ****************** **.*:**.*.*******************************:**.********. ***:* **.**************: *** ** *: *:***** *. . *: *:***:******.*** *:** .** * *** .*****.** . *.** ******:*******************::****.*:**** :******:***** .****.::****: **:********:***** *.*************:******.*****************:**********:**:***:****:**:*.*:***:********** *** *::**. .*:**:*::**:*****.** :.************::******:****:******:******:.*****************:****** *::*******:***.***.: **: **********************************.******.**:*************:***** .*********************** :*********.****:******:******************.* *:***************.********.********* :* :****: *.*********** ***** * ::********.********::::::*:****.**********************:******************:******************** *:********* ******:***:********:****.*******. **:*: ***:******:****:***********.************************:*****:.:**********:********** ************************", "identical_positions": 803, "similar_positions": 139, "identity": "26.83%" }, { "cls_id": "homologset.agr.HGNC:3443", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0L5-1", "uniprot_id": "EREG_RAT", "id": "Q9Z0L5-1", "name": "Proepiregulin", "aln": "------METFPAAWVLA-LLCLGSHLLQAVISTTVIPSCIPEESEDNCTALVQMEDDPRVAQVLITKCSSDMDGYCLHGHCIYLVDMSEKYCRCEVGYTGLRCEHFFLTVHQPLSREYVALTVILVFLFLIVTAGSMYYFCRWYRNRKSKKSREEYERVTSGGPGLPQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61521-1", "uniprot_id": "EREG_MOUSE", "id": "Q61521-1", "name": "Proepiregulin", "aln": "------METLPASWVLT-LLCLGSHLLQAVISTTVIPSCIPGESEDNCTALVQMEDDPRVAQVQITKCSSDMDGYCLHGQCIYLVDMREKFCRCEVGYTGLRCEHFFLTVHQPLSKEYVALTVILIFLFLIITAGCIYYFCRWYKNRKSKKSREEYERVTSGDPVLPQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14944-1", "uniprot_id": "EREG_HUMAN", "id": "O14944-1", "name": "Proepiregulin", "aln": "MTAGRRMEMLCAGRVPALLLCLGFHLLQAVLSTTVIPSCIPGESSDNCTALVQTEDNPRVAQVSITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLTVHQPLSKEYVALTVILIILFLITVVGSTYYFCRWYRNRKSKEPKKEYERVTSGDPELPQV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : *. * : ***** ******:********** **.******** **:****** ********:******:******* :::*********:**************:*********::**** ..*. *******:*****:.::********.* ****", "identical_positions": 126, "similar_positions": 24, "identity": "74.56%" }, { "cls_id": "homologset.agr.HGNC:34430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1IGU3-1", "uniprot_id": "ARH37_RAT", "id": "A1IGU3-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "----------------------------MADFETDEASSKSESPEQEGQGSEDKSLLHQRLAIRELIDTEVSYLHTLRLCTSDIRGHLQQLPPG--DLDILFSNIDDIIQVSSRFLHGLQETACKEEKQ--AHLIGNLFLEFQEELEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAVPQAGPSGLSFLLVIPLQRITKYPLLLQKILENTPADASAHPVLQRATSALQDVNSNINEYKMRKEVALKYTKVEQLSLRERLARINTHTLSKKTTRLSQLLKQEAGLVPRTEDKEFDDLEERFQWVSLCVTELKSNVAAYMDNLEAFLCFRPHERNLDIPGG-AAEQYCSLARDLQLQAFLQFKQRLTGLVWQPLCSLARALVGPQNLIKKRLDKLLDFERVEEKLLDVGSVTYEEEAARHTYQALNSLIVAELPQFNHLVMQWLGQILRTFVVLQRDLADQVLRRAESSMALLPHRHVSEPDFQKLLEDTLGQSSSQLRHFRESFEKVLPPSTSQPLLPGSEHQMQSLLTRYGPGKIYQVTSNINGTGTLDLTLPRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQLYHPINPSEKEPRRQ----TGMPEDYWLPTPEPTQPSVPTVPTMSQVVAVYPFVARSTHELSLQAG-------QPVTILEAQDK-----KGNPEWSLVEANGQR----GYVPSNFLARTPSPTPRGWNLPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1IGU4-1", "uniprot_id": "ARH37_MOUSE", "id": "A1IGU4-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "----------------------------MADFGADEASSKSESPEQEDQGSEDRSLLHQRLAIRELIDTEVSYLHTLRLCASDIRSHLQQLPPG--DLDILFSNIDDIIQVSSRFLRGLQETACREEEQ--AHLIGNLFLEFQEEFEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAMPQAGPSGLSFFLVIPLQRITKYPLLLQKILENTPADASAHPALQRATSALQDVNGNINEYKMRKEVALKYTKVEQLSLRERLARINTHTLSKKTTRLSQMLKQEAGLVSRTEDKEFDDLEERFQWVSLCVKELRNNVVDFMGNLEVFLSFRPHERSLDIPGG-PAEQYCSLARDLQLHAFLQFKQRLRSLVWQPLCSLARALAGPQNLIKKRLDKLLDFDRVEEKLLDVGSVTWEEEAARHEYQALNSLLVAELPQFNQLVMQWLGQILCTFVVLQRDLADQVLRRAESTMALLPHHHVSEPDFQKLLEHTLGQSSSQLRLFQESFEKVLPPSTTQPLLPGSEHQMQALLTRYGPEKLYQVSSNINGTGTLDLTLLRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQLYHPIIPSEKELRGQ----TGTHEDSWLPAPEPTQLSVPTVPTMSQVVAVYPFVARSTHELSLQAG-------QPVTILEAQDK-----KGNPEWSLVEANGQR----GYVPSNFLARTPSPTPWGWNLPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1IGU5-1", "uniprot_id": "ARH37_HUMAN", "id": "A1IGU5-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "----------------------------MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTEVSYLHMLQLCASDIRSRLQQLPQG--DLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQ--VQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIVEAVVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQDVNTNINEYKMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEG-PAVQYCNLARDLHLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQEEAARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQLPHHHVPEPAFRKLVEDALGRTSNQLRSFQETFEKVQPPPTTQPLLPGSERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGRWLVDTGGHRGYVPAGKLQLYH-VVPSAEELRRQ----AGLNKDPRCLTPEPSPALVPSIPTMNQVIAAYPFVARSSHEVSLQAG-------QPVTILEAQDK-----KGNPEWSLVEVNGQR----GYVPSGFLARARSPVLWGWSLPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H7J0-1", "uniprot_id": "A0AC58H7J0_DANRE", "id": "A0AC58H7J0-1", "name": "", "aln": "MANSLKANITLTVDEETEGAKEMDNALEELAEEEEDEEERKARVAAEEAAARERAAQRQLMAIEEMVHTEKNYLKHLQICTVTINSNLQKLQPPPPNLENMFQHIDEVMEVSSRLLSLLDQAQMQHSDPKYLETLCDSFLSLSQDIEMAYKEYLANYNNITALENSYKQKEALWMEMVRIIKSSAPDVNASTLSFFLVMPVQRIARYPLLFQTIQKHTDPQHPAYPELEHTAHTAIQINCRINEYKRFREVADKYKKTENLTIKDKLNRLSGHSIAKKTARFSQYIKHETGMVPKLKDEEFDALAGFFFVLERGVSELHDNLLTYLHHLQRFLSCRPEEADLDLEGEKTALFSKEITVALRQWIYPSYEKRLKTLVFKPLSSLRELMAGPRNLIRKRQDKLLDYEPIEEK----SNLTFEEQAIANTYKTMNTLLLNELPQFNGKALQLMWAALEAFSVLQRDLATDMEQLATSFTHQLPHSYLEAGDFWKWAETSVLEGSWRMESLCRSVQDELNAPIVQALNTVSKKRLMYLNANHGSEKIYQLTGPVVGTRDLDLTLNKGELVAVVCEMDTRGDRRRWLVDAGGPRGYVPASKLARYHQLTIDPPQSPHLNVTPTGPGPRRHSYTPGAQPHLTTITTPCFQVYAGYDFTARSAHELSLRAGSLCGSLFRRFWLLQMEGSGVSQITSNRVLALLAVSGQEPWGNAVAQTQFYPFPMSLECEGVRIKIFP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ..:. * .:.::: :* :*:.*::.** .**: *::*: *...**:* :*: :*.:**::::*.**:* *::: :... . : : **.:.:::* .** * *.*:: * .:*::: * .: *::: *:...* ***:**:*:***::****:*.* ::* .: .*:* *:::. : ::* .***** :*** **.*.*:*:::::* *:. *:::***:*:** :*:*:*::.: :*:*** * * :. *.**:.*: :: :*: ** **.* .**: .* .:: *: : .:::** **::**.** . : **:***:** *****:: :*** ..:*::*:* : *:::*:*:: ****** .:* : : :* .****** :: : * . *** :: * * * :: . * ::. : .:.:. .. *.* . *:::: * :.:*. *:**::. : ** ***** :*::**:: : **:*: *****:** ******.** ** : . : :* :* . .. .. ** * * *.***:**:**:** : . :*: :.. ..* :*: ..**. . . : * . . * * : ", "identical_positions": 215, "similar_positions": 250, "identity": "29.41%" }, { "cls_id": "homologset.agr.HGNC:34431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJR9-1", "uniprot_id": "A0ABK0LJR9_RAT", "id": "A0ABK0LJR9-1", "name": "", "aln": "------MDVPGGVCSRSGALSSADPAPASVTLAELLHLVQKGQELPGLEKRHITATHGEPTVSLLPRKSKPWEDAGSAAS--SCTAALDSRTQPPTIEEPSRGSPAYQLDGGPRDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D727-1", "uniprot_id": "PEX39_MOUSE", "id": "Q9D727-1", "name": "Peroxisomal biogenesis factor 39", "aln": "MSWWQDMDQRGGVSSPSGALASAEPAPASVTLAELLHLVQKGQEVPGLEKRHITATHGEPTASLLPRRPKPWEDAGSAAS--PCTIALDTRTQPPTIEERSRGSPAAQLDGGPRVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0X4-1", "uniprot_id": "PEX39_HUMAN", "id": "Q5I0X4-1", "name": "Peroxisomal biogenesis factor 39", "aln": "------MERP-----RSPQCSAPASASASVTLAQLLQLVQQGQELPGLEKRHIAAIHGEPTASRLPRRPKPWEAAALAESLPPPTLRIGTAPAEPGLVEAAT-APSSWHTVGP---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * ::. .*.******:**:***:***:********:* *****.* ***:.**** *. * * . * :.: . * : * : :*: ** ", "identical_positions": 48, "similar_positions": 24, "identity": "41.38%" }, { "cls_id": "homologset.agr.HGNC:34433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNG0-1", "uniprot_id": "A0ABZ3NNG0_RAT", "id": "A0ABZ3NNG0-1", "name": "", "aln": "MLRAFCFLNPKLGSPWKSEPESRPSLYTRLPNSCLGSSSTTPFTAMDLHLLCLLLFLVTSLPEGYCVIGNSGVSFKPCTSEGGYCFFGCKLGWIWITYCNNIMSCCKKDTKHSLPQTKG--V-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVB5-1", "uniprot_id": "DFB42_MOUSE", "id": "Q8BVB5-1", "name": "Beta-defensin 42", "aln": "---------------------------------------------MNLRLSCLLFILVTSLPAGRCSIGNKGISFETCTAIEGLCFFGCKLGWVWIAYCNNIMSCCRKDTDFVLPQTKG--I-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q30KP8-1", "uniprot_id": "DB136_HUMAN", "id": "Q30KP8-1", "name": "Defensin beta 136", "aln": "---------------------------------------------MNLCLSALLFFLVILLPSGKGMFGNDGVKVRTCTSQKAVCFFGCPPGYRWIAFCHNILSCCKNMTRFQPPQAKDPWVH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* * .**::** ** * :**.*:....**: . ***** *: **::*:**:***:: * . **:*. : ", "identical_positions": 33, "similar_positions": 24, "identity": "26.83%" }, { "cls_id": "homologset.agr.HGNC:34434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E8G2-1", "uniprot_id": "U17PD_MOUSE", "id": "G5E8G2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein D", "aln": "---------------------------------------------------------------------------------MVVSLSFPEADPALSSPG-------------------------------------AQQLHQDEAQVVVELTANDKPSLSWECPQ---GPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCC----SPEGCKMCAMEAHVTQS---LLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHR---QSEPTSEDSSPIHDIFGGLWRSQIKCLHCQGTSDTYDRFLDVPLDISSAQSVNQALWDTEKSEELRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGNKLDRKVSYPEFLDLKPYLSQ---PTGGPLPYALYAVLVHEGATCHSGHYFSYVKAGHGKWYKMDDTKVTSCDVTSVLNENAYVLFYVQQTDLKEV-------SIDMPEGRIHEVLDPEYQLKKSRRKKHKKKSPCTEDVGEPSKNREKKATKETS-----------LGEGKVLQ-----------------------EKNHKKAGQKHENTKLVPQEQNHQKLGQKHRNNEILPQEQNHQKTGQSLRNTEGELDLPADAIVIHLPRSIANWGRD-------TPDKVNQPWHNADRLLTSQDLVNTGQLCRQEGRRRSKKGKNKNKQGQKLLLVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E8I7-1", "uniprot_id": "U17LC_MOUSE", "id": "G5E8I7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein C", "aln": "---------------------------------------------------------------------------------MVVSLSFPEADPALSSPG-------------------------------------AQQLHQDEAQVVVELTANDKPSLSWECPQ---GPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCC----SPEGCKMCAMEAHVTQS---LLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHR---QSEPTSEDSSPIHDIFGGLWRSQIKCLHCQGTSDTYDRFLDVPLDISSAQSVNQALWDTEKSEELRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGNKLDRKVSYPEFLDLKPYLSQ---PTGGPLPYALYAVLVHEGATCHSGHYFSYVKARHGAWYKMDDTKVTSCDVTSVLNENAYVLFYVQQTDLKQV-------SIDMPEGRVHEVLDPEYQLKKSRRKKHKKKSPCTEDAGEPCKNREKRATKETS-----------LGEGKVLQ-----------------------EKNHKKAGQKHENTKLVPQEQNHQKLGQKHRINEILPQEQNHQKAGQSLRNTEGELDLPADAIVIHLLRSTENWGRD-------APDKENQPWHNADRLLTSQDPVNTGQLCRQEGRRRSKKGKNKNKQGQRLLLVC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61068-1", "uniprot_id": "U17PA_MOUSE", "id": "Q61068-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein A", "aln": "---------------------------------------------------------------------------------MVVALSFPEADPALSSPD-------------------------------------APELHQDEAQVVEELTVNGKHSLSWESPQ---GPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCC----SPEGCKLCAMEALVTQS---LLHSHSGDVMKPSHILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHR---QSKPTSEDSSPIHDIFGGWWRSQIKCLLCQGTSDTYDRFLDIPLDISSAQSVKQALWDTEKSEELCGDNAYYCGKCRQKMPASKTLHVHIAPKVLMVVLNRFSAFTGNKLDRKVSYPEFLDLKPYLSE---PTGGPLPYALYAVLVHDGATSHSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQANLKQV-------SIDMPEGRINEVLDPEYQLKKSRRKKHKKKSPFTEDLGEPCENRDKRAIKETS-----------LGKGKVLQ-----------------------EVNHKKAGQKHGNTKLMPQKQ-------------------NHQKAGQNLRNTEVELDLPADAIVIHQPRSTANWGRD-------SPDKENQPLHNADRLLTSQGPVNTWQLCRQEGRRRSKKGQNKNKQGQRLLLVC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7M764-1", "uniprot_id": "U17PE_MOUSE", "id": "Q7M764-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein E", "aln": "-----------------------------------------------MVVSLSFPEETGGENLPSAPLEDSSKFFEEVFGDMVFARSFPEADPALSSPD-------------------------------------APELHQDEAQVVEELTTNGKHSLSWESPQ---GPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCC----SPEGCKMCAMEAHVTQS---LLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHR---QSDPTPQDTSPIHDIFGGWWRSQIKCLHCQGTSHTFDPFLDVPLDISSAQSVNQALWDTGKSEELLGENAYYCGRCRQKMPASKTLHVHIAPKVLLLVLKRFSAFTGNKLDRKVSYPEFLDLKPYLSE---PTGGPLPYALYAVLVHDGATSNSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQTDLKQV-------SIDMPEGRVHEVLDPKYQLKKSRRKKRKKQCHCTDDAGEACENREKRAKKETS-----------LGEGKVPQ-----------------------EVNHEKAGQKHGNTKLVPQEQ-------------------NHQRAGQNLRNTEVELDLPVDAIVIHQPRSTANWGTD-------APDKENQPWHNGDRLLTSQGLMSPGQLCSQGGR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q9U0-1", "uniprot_id": "U17PB_MOUSE", "id": "E9Q9U0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein B", "aln": "---------------------------------------------------------------------------------MVVALSFPEADPAMSPPS-------------------------------------APELHQDEAQVVEELAANGKHSLSWESPQ---GPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCC----SPEGCKMCAMEAHVTQS---LLHTHSGDVMKPSQNLTSAFHKRKQEDAHEFLMFTLETMHESCLQVHR---QSEPTSEDSSPIHDIFGGWWRSQIKCHHCQGTSYSYDPFLDIPLDISSVQSVKQALQDTEKAEELCGENSYYCGRCRQKKPASKTLKLYSAPKVLMLVLKRFSGSMGKKLDRKVSYPEFLDLKPYLSQ---PTGGPLPYALYAVLVHEGATCHSGHYFCCVKAGHGKWYKMDDTKVTSCDVTSVLNENAYVLFYVQQNDLKKG-------SINMPEGRIHEVLDAKYQLKKSGEKKHNK-SPCTEDAGEPCENREKRSSKETS-----------LGEGKVLQ-----------------------EQDHQKAGQKQENTKLTPQEQ-------------------NHEKGGQNLRNTEGELDRLSGAIVVYQPICTAN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6R6M4-1", "uniprot_id": "U17L2_HUMAN", "id": "Q6R6M4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17", "aln": "---------------------------------------------------MEDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSP-LSSEA-------------------------------------RVDLCDDLAPVARQLAPRKKLPLSSRRPA---AVGAGLQNMGNTCYENASLQCLTYTPPLANYMLSREHSQTCQ----RPKCCMLCTMQAHITWA---LHS--PGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHK---QVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKLAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAKVTACSITSVLSQQAYVLFYIQKSEWERH-------SESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAP-ELDERLVERATQEST-----------LDHWKFPQ-----------------------EQNKTKP--------------------------------------EFNVRKVEG--TLPPNVLVIHQSKYKCGMKNH-------HPEQQSSLLNLSSTTRTDQESVNTGTLASLQGRTRRSKG--KNKHSKRALLVCQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRP5-3", "uniprot_id": "UBP36_DROME", "id": "Q9VRP5-3", "name": "Ubiquitin carboxyl-terminal hydrolase 36", "aln": "MPVSMAVCETANVVNAALRESLGGNSSAGSSTDQAKSGEDTNGSLQNHIVANAKRILMAKIEYEEVPNYHESVLENLKSKYIVIKPGNPGAINGFSGKNNTGKLVGANGHDNNGARKQAEHPNNQSHHINHHNHQHPTSNPNELPKPKRVLYPRENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAMTKTLLATQSNQSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKELDQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKADSLEDAFEGHFSRERLEDMG-YKCEGCKKKVSATKQFSLERAPITLCIQLKRFS-MIGNKLTKQISFKSRIDLSKYAARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFFELDLSQAASPAANRPNGVRLTNGHSTTPVPAATVSSPSPTRFIGPQLPAGGANGYTNGNAQKTAIQFKQQNQQSPQNGLQLGTGKFQDTAKPPLVGAHAKGEATSAPTANGNKSSSPSSNSSSNHKSINQQQYLPISSDDEDIEDEMKPRPTTAQLPSMPNMTENHTEPKAKSPVKIQVKTPVKTPLKSLVPYESASEEEEAPLPNPRKRPSGEDSSESDQESGQTNGHSKTNGSHTNGSASSSVHVNNSKQKTDAIDEIFKSLKKSADSDEDDDEEEPSIQLTNGWHPQKQSQSQSKAPPSPKTPPSPAVIKSKTGIWKVTRNDEVDAIEDDVDVVVVEGSPVKIPTPNKNHRNPFSSSKPSTDSPATPGAKRQKLLNGSALKSHQQPRVGNGYQSNATSNGSTINELLKQSYRGYGSPVLSWNGKPAELEKELLVDAREQRQRDIDDDEENEMDRGRQRKVKSGSAKGNNASNSTPGYNPFQEYEGQKRWNKNGGGGGFPRFYNQNYRQNFQQRNKFKFNRFGGPGSAKFQQQRALQRHLSAGGGFSRRQPSAQQQQQT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53874-1", "uniprot_id": "UBP10_YEAST", "id": "P53874-1", "name": "Ubiquitin carboxyl-terminal hydrolase 10", "aln": "----------------------------------------------------------MTTQESIKPLVDRILSNPLQFNAAMISNKSNNNDTSAAPENSS---------------------------------YIVIGKQHNNNSNSTAIAATAESKQIKENNLIDRPNGKKTNTVPKSMAEALLLYTSKNDKDAADATGAKKSAELSTELSTEPPSSSSEDDKVGKEEEEEGEIFHEARDYVEPRKASLKERDNADKGDGEDIGEDIGEDIGEDIGEDIG----EDIGENLGSPLATIDDSSNENEKEKRKELSTSISSDDEIEDDEDEDDMDYDSSAMEKELPEEEENDSSSKISE--GEKKSLYQDLMENSTVEVNRYEPVNNTKENGNRNPKGEEEEEEEEELKHKSRSITPPVTISNLSNFYQFNENINDRGSLNSTRIVKNWGDKFTNLKPRGLLNHGVTCYTNAAVQAMLHIPSIQHYLF---------DILMGKYDSTISKNSVSYTLAETSKKMWLPVSKNPRKNVSASYINPKHLISRLDDIN---CMMSEWQQED-----------------------SHEYFMSLMSRLQEDSVPKGHKLIESIIYDIFGGLLKQIVTCKSCGSISKTEQPFYDLSLHLKGKKKLDPNSDLSSD-------SINGTSATTSTTTSNAATKPSLSSSSSVNLNNGSPFAAASDLSSANRRFSIEKSIKDFFNPELIKVDKEQKGYVCEKCHKTTNAVKHSSILRAPETLLVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCESKELPVKYQLLSVVVHEGRS------------------------------LSSGHYIAHCKQPDGSWATYDDEYINIISERDVLKEPN---AYYLLYTRLTPKSVPLPLAKSAMATGNVTSKSKQEQAVNEPNNRPLKINSKKNNRKKWKKNKKRKFTK----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : : . * . :: * *: :.: . . . : : *..:: : : . . : : : * .. ..: . * : : : * : ..*: *. . . . :: . : : : . . : *:: : . . : : :. . . : . . : ::. : : . . . ::. . . : *: : . : :. : : . . . . : ", "identical_positions": 11, "similar_positions": 98, "identity": "1.06%" }, { "cls_id": "homologset.agr.HGNC:34435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK60-1", "uniprot_id": "KLH38_RAT", "id": "Q5BK60-1", "name": "Kelch-like protein 38", "aln": "---------MDEELPDAVVFKDQNFSSDLLRQLNGLRQSKILTDVSICSGACEVPCHRNVLASSSPYFRAMFCSHFRESREAKVQLKGISSTTLEQVIAYVYTGEVHISAANVLPLMEAAAMLQYPRMFEACSSYLQSQLAPSNCLGLVRLAEILSCDSLKKKAREVALTYFPEVAASADLKELCVMELRDYLGDDKLCGEEEKVFEALMAWVKHDLQARWRYMQELLQQVRLQYIHPAFFHHFIASDALLQSSPACQAILEMAKKQIFSLYGPSAQDCK-LWHTPPRSSYQDFLLLLGGRKDNQQTTRDVLLYSIQTGQWQSLAKLPTRLYKASAVTLHRSVYVLGGMAVREGK--GLISCSVYIFSMKLNQWRMGEPMLAARYSHRSTTHRNFIFSIGGTGEGQELLGSMERYDSIRDVWESMADMPMAVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNTWYKMETRMIKNVCAPAVVLGEKIIIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHTLFDHACLTLQCIPHMTSLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSF5-1", "uniprot_id": "KLH38_MOUSE", "id": "Q8BSF5-1", "name": "Kelch-like protein 38", "aln": "---------MDEELPDGVVFKDHSFSSDLLRQLNGLRQSKILTDVSICSGAWEVPCHRSVLASSSPYFKAMFCSHFRESREAKVQMKGISSTTLEQVITYVYTGEVHISAANVLPLMEAAAMLQYPRVFEACSSYLQSQLAPSNCLGLVRLAEILSCDSLKKKAKEVALTYFPEVAASADLKELCAMELRDYLGDDRLCGEEEKVFEALMAWVKHDLQARWRHMQELLQQVRLQYIHPAFFHHFIANDALLQSSPACQAILEMARKQIFSLYGPSAQDCKLLWRMPPRSSYQDFLLLLGGRKDNQQTTRDVLLYSGQTGQWQSLAKLPIRLYKASAVTLHRSVYVLGGMTVSEGK--SLISCGVYIFSLKLNQWRVGEPMLAARYSHRSTTHRNFIFSIGGTGEGQELLASMERYDSIRDVWESMAGMPVAVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNTWYKMETRMIKNVCAPAVVLGEQIVIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHKLFDHACLTLQCIPHMTSLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2WGJ6-1", "uniprot_id": "KLH38_HUMAN", "id": "Q2WGJ6-1", "name": "Kelch-like protein 38", "aln": "---------MDEESLDGLLFKDHDFSSDLLRQLNSLRQSRILTDVSICAGAREIPCHRNVLASSSPYFRAMFCSSFREKSEAKVQLKGIDPPTLDQIVSYVYTGEAHIATDNVLPVMEAASMLQFPKLFEACSSYLQSQLAPSNCLGMIRLSEILSCETLKKKAREVALTSFPEVAASADLKELCALELRDYLGDDGLCGEEEKVFEALMVWIKHDLQARKRYMQELFKQVRLQYIHPAFFHHFIANDALLQSSPACQIILETAKRQMFSLCGTTVPDCKLLLHVPPRNSYQDFLILLGGRKDSQQTTRDVLLYSKQTGQWQSLAKLPTRLYKASAITLHRSIYVLGGMAVSSGR--SLVSHNVYIFSLKLNQWRLGEPMLVARYSHRSTAHKNFIFSIGGIGEGQELMGSMERYDSICNVWESMASMPVGVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNSWFKMETRMIKNVCAPAVVLGERIVIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHKLFDHACLTLQCIPRTSGLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYM6-1", "uniprot_id": "KLH38_DANRE", "id": "Q1LYM6-1", "name": "Kelch-like protein 38", "aln": "---------MASTSTEVFPFKDQELSTQLLFQLNILRQEQIFTDVILCTEDKEIPCHRNVLVSSSPYFRAMFCSNFRESSQARVDLKGIASEVIECVVDYIYTGSITITMELVLPLMQAASMLQYGRLFEACSTFLQEQLNPENCLSMIRLSEILHCETLKERAKEMAVRCFSDVAASEDFCELTLPELMCYLEDDRLCAEEEQVFETLLAWIHHDPFSRRGAIHDLFKKVRLRFIHPTYLFQFIANDPLVQSSTLCTEIIESVRRLMFSVSAKCTKELKPLWTTPRRYTCRETLVVVGGRKNNEQTSREALLYDERTQRWQWLAKLPLRLYKAAYVCIHSILYVVGGLSLSLVSGDSAVSATVYTLSLKTNQWRTAEPMLEPRYAHQCVSYLHFIFALGGIGQDKQISNTVERYNSMFNQWEVMAPMPTAVLHPAVAANDQRIYVFGGEDALQNPVRLIQVYHISRNLWSRLETRTVKNVCAPAAVIEDKIYIVGGYTRRVIAYDTKANKFVKCTNMKERRMHHAATVINNKLYVTGGRFLNSHDVIEDSDCFECYDPKTDVWTSKGSLPYKLFDHGSLPLICVSNRPNPP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X1WG55-1", "uniprot_id": "X1WG55_DANRE", "id": "X1WG55-1", "name": "", "aln": "MCFKSAETSLDGPVSEILHFKDKDLISNLLLELNTLRKDRILTDVVLCSENKEIPCHRNVLVSSSPYFHAMFCSNFLETQKSRINLEGVPHEILAMIVEYVYTGSISISMELVLPLIQTASMLQYGRLFEACSTFLQAQLSADNCLSMIRLSEILHCSSLHEKARELAIKSFSDVVVSEDFCELSLPELVSYLEDDKLCVEEEQVFETLLAWIHHDPFSRHGTIHDLFRRVRLRHVHPYYLFQFIANDPLVQSSSLCTDIIESVRRLLFSVGTHCPGDLEPLWRTPRRQNCKEGLVVVGGRKNGEQTSREALLYDEQSHCWKWLAKIPLRLYRPAYVCMHSILYVLGGLTMKSGS-QCTPSNTVYTLSLKTNQWRMGESMLTSRYGHQSATYLHFIFVLGGLGADGQLSNEVERYDTMFNQWEAMAPMPTAVLHPAVAAHNQRIYVFGGEDAMQKPVRMIQVYHIGRNMWCRIENRTVKNVCAPAAVIDDKIYIVGGYTRRMVAYDVKSNTFEKCENMKARKMHHSATVVNGKIYVTGGRFFNSHERVEDSDSFDCFDPKTDAWTSMGKLPFKLFDHGSVPLVYLSDKFLPT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ***:.: ::** :** **:.:*:*** :*: *:****.**.******:***** * *. :::::::*: : :: *:***. *: ***::::*:***: ::*****::** ** ..***.::**:*** *.:*:::*:*:*: *.:*..* *: ** ** ** ** ** ***:***:*:.*::** :* :::*:::***:.:** ::.:***.*.*:***. * *:* .:: :**: : : * * * . :: *:::****:.:**:*:.***. :: *: ***:* ***:.: : :* :**:**::: * ** :*:* **** .*.** .**.*:..:: :*** :** * . :: :***::: : ** ** ** .*******.::**:*:***** :*:***:******.** * ::*.* :*******.*: ::* ********::*** ::*.* ** :** *:***.***:..*:****** :.:. :*** .*:*:**:**.*** *.**..****..:.* :. .", "identical_positions": 260, "similar_positions": 193, "identity": "43.92%" }, { "cls_id": "homologset.agr.HGNC:34437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9J5-1", "uniprot_id": "A0ABK0L9J5_RAT", "id": "A0ABK0L9J5-1", "name": "NELL2-interacting cell ontogeny regulator 1", "aln": "MAP--APRSLLSPP-ILLLLLLLSLALLGARAEPA-AGSAVPAQSRPCVDCHAFEFMQRALQDLRKTAYSLDARTETLLLQAERRALCACWPAGR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UR78-1", "uniprot_id": "NICOL_MOUSE", "id": "Q3UR78-1", "name": "NELL2-interacting cell ontogeny regulator 1", "aln": "MAP--ALRSLLSP--RTLLLLLLSLALLGARAEPA-TGSAVPAQSRPCVDCHAFEFMQRALQDLRKTAYSLDARTETLLLQAERRALCACWPAGR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BLP8-1", "uniprot_id": "NICOL_HUMAN", "id": "Q5BLP8-1", "name": "NELL2-interacting cell ontogeny regulator 1", "aln": "MAPPPACRSPMSPPPPPLLLLLLSLALLGARARAEPAGSAVPAQSRPCVDCHAFEFMQRALQDLRKTACSLDARTETLLLQAERRALCACWPAGH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEX9-1", "uniprot_id": "E7FEX9_DANRE", "id": "E7FEX9-1", "name": "NELL2-interacting cell ontogeny regulator 1", "aln": "MRP----SGALAA--AAVMLMLL----VCCQAEDS--GSVIPAESRPCVDCHAFEFMQRALQDLKKTAFNLDSRTENLVLRAEKRALCDCMPASSLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . ::. ::*:** : .:*. **.:**:********************:*** .**:***.*:*:**:**** * **. ", "identical_positions": 49, "similar_positions": 22, "identity": "50.52%" }, { "cls_id": "homologset.agr.HGNC:34438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M7D1-1", "uniprot_id": "F1M7D1_RAT", "id": "F1M7D1-1", "name": "", "aln": "MDQNSEGSMKKTSTVNLDKLIDDFSQIEKKMIEVTGKNNLLDIRLEKTNSLLKIMQAKETSMKEECITLHTMIKGLQQTVQYQHNLKGENEQLKRNVDFMKEKLKSHEQEYKNNIAKLISEMKIKEEEHKIELSKLYQDMQKKVELNEEKHKELMAKKEMEISELNATLKTQEKEKRNEILRLHIEFDTKLARAQTKSKPYPEATILPQSIYRRKLQHLQEEKNKEIASLQNTIRDLEQRLAASKDTRLTRRRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PX14-1", "uniprot_id": "E9PX14_MOUSE", "id": "E9PX14-1", "name": "", "aln": "MDQNSEECTKKIRTVNLDKLIDDFSQIEKKMIETAGKNNLLDIQLEKTNSLLKIMQTKETSMKEECIILHTMIKGLQQTVQYQHNLKDENEQLKRNVDFMKEKLKSHEQEYKNKIAKLISEMKIKEEEHKTEMSKLYLDMQKKVELNEEKHKELMARKEMEISELNAKLRTQEKEKQNEILRLHLEFDTKLARAQTKSKSYPDTTILLQSIYRRKLQHLQEEKSKEIASLQNTIRDLEQRLAACKDTRLMRRRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0S7-1", "uniprot_id": "CC152_HUMAN", "id": "Q4G0S7-1", "name": "Coiled-coil domain-containing protein 152", "aln": "MDQSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSHLKRRRF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.** . ** :*******:*********:*. ****:***:***:*.***:**:**.*:**** **.:*******::**:***.****** ..*::*************:****:******** :* *:**** ***:************: :**********.*::*****:***::*::***:****.*****.* ::*:* **********:****.**** *:**********:. **::* ****", "identical_positions": 185, "similar_positions": 52, "identity": "72.83%" }, { "cls_id": "homologset.agr.HGNC:34439", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLU7-1", "uniprot_id": "D3ZLU7_RAT", "id": "D3ZLU7-1", "name": "", "aln": "MFAQSKSEKTEDILTLSTVAFETKAITFFIILLICFFCILLLLAMFLYKCYRSQSFEEAMRPLCTGENDDENCLAVNTQMSRPEVNDKVLLHFVNMNMPVRPGILVQRQNKKEMATSLGD----IKTEEYRNRQTYEPAISRETKHEG-EFAEKIPIHVHRTPTDR-SQKRPIKGVTFSKEVIVVDLGNEDATPRSYAREHKERK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810S2-1", "uniprot_id": "CB074_MOUSE", "id": "Q810S2-1", "name": "Uncharacterized protein C2orf74 homolog", "aln": "MFTQSDTGKIEEIFTTNTMAFETTAITFFFILLICFICILLLLAIFLYKCYRGHNHEEPLKTLCTGEG----CVAANAEMDKPEDQDKVLMHFLNMGLPMKPSILVQKQSKEEMATSLGDN---IKAEDYQKKQTYEPVNARETNHEG-ELAEKMPIHVHRSSDTG-SQKRPLKGVTFSKEVIVVDLGNEYPTPRSYAREHKERK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MZ97-1", "uniprot_id": "CB074_HUMAN", "id": "A8MZ97-1", "name": "Uncharacterized protein C2orf74", "aln": "------------------MSFETTAITFFIILLICLICILLLLVVFLYKCFQGRKGKETKKVPCTDANGGVDCAAAKVVTSNPEDHERILMQVMNLNVPMRPGILVQRQSKEVLATPLENRRDMEAEEENQINEKQEPENAGETGQEEDDGLQKIHTSVTRTPSVVESQKRPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::***.*****:*****::******.:*****::.:. :*. : **. . * *.:. ..** ::::*::.:*:.:*::*.****:*.*: :**.* : *: : .:. ** : ** :* : :*: * *:. *****:******:********** .*****:*******", "identical_positions": 86, "similar_positions": 59, "identity": "41.95%" }, { "cls_id": "homologset.agr.HGNC:3444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUR4-1", "uniprot_id": "A0ABK0LUR4_RAT", "id": "A0ABK0LUR4-1", "name": "", "aln": "MGGGCRGSLFVLPPLTDSAPLSAGRLFPPPLSSPPSCSSLRGQGSPPPPIAGRGAAGLTPPSHSDFPPSPPPPPPGLHRLDFAPGRAGGRGPRRPLPVCPVGIRPGAGTREGEGGRAPLFKLVSFPRRRPRLRLLCAGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPELGAFRGPPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAPGGTDKSSDGSGSGGLAEGAGALAPPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGAAQCMPLKLRFKRRWSEDCRLEGGGCLSGGPEDEGEDKKVRGDMGPGEPGGPLTPRRVSSDLQHATAQLSLEHRDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70459-1", "uniprot_id": "ERF_MOUSE", "id": "P70459-1", "name": "ETS domain-containing transcription factor ERF", "aln": "------------------------------------------------------------------------------------------------------MKTPADT----------------------------GFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFIDMGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPELGAFRGPPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAPGGTDKSSGGSGSGGLAEGAGAVAPPPPPP-QIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGVAQCMPLKLRFKRRWSEDCRLEGGGCLSGGPEDEGEDKKVRGDVGPGESGGPLTPRRVSSDLQHATAQLSLEHRDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50548-1", "uniprot_id": "ERF_HUMAN", "id": "P50548-1", "name": "ETS domain-containing transcription factor ERF", "aln": "------------------------------------------------------------------------------------------------------MKTPADT----------------------------GFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKS--GGSAGGLAEGAGALAPPPPPP-QIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGE-GPGEAGGPLTPRRVSSDLQHATAQLSLEHRDS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. *.* *****************************************************************************************************************:*******************************************************************************************:************************************************************************************************************************************************************************************** .*:*** *..:*********:******* **************************************************.:*********************** :** ***********: ****.***************************", "identical_positions": 526, "similar_positions": 17, "identity": "77.13%" }, { "cls_id": "homologset.agr.HGNC:34440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0X0-1", "uniprot_id": "D4A0X0_RAT", "id": "D4A0X0-1", "name": "", "aln": "MPLTLSRDMTIQKTGGRGRAAAELLEQRRSSHHCDDRKQTLLALLVLVLYLGTGISGSSWEVSGRTKDCNHFQTTVTSQDFEYQTKEPAEEPLRALRKWLKTNLHGFLEKLEKEVRELEQLVRDLEFWLDALLGEPHSEDPCFTTK------VICEGQVQGPGEQKRR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAL0-1", "uniprot_id": "SIM23_MOUSE", "id": "Q9DAL0-1", "name": "Small integral membrane protein 23", "aln": "--------MTIQKTGCRGREAAEVVEQRRRSHHCDDRKQTLLALLILVLYLGMGISGSSWEVSGQTKDCNHFQNPVTPQGFEYQTKEPAEEPLRTLRKWLKINLHGFLEKLEKEVRELEQLVRDLEFWLDALLGDLRPEDPCFT--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NLE4-1", "uniprot_id": "SIM23_HUMAN", "id": "A6NLE4-1", "name": "Small integral membrane protein 23", "aln": "---MATQQVDSRRQVAAEQVAAQLLERRRGS-HCDDEKQTLLALLILVLYLSTEIWGSSWEVSERIRECNYYQNLAVPQGLEYQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHCSTYKSHLWEWAWALGREHKGGEGLLEISLSGAEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : **:::*:** * ****.********:*****. * ******* : ::**::*. ...*.:****:**:***::::*:*** :** * ****:**::****. ***:*******: : *: * * ", "identical_positions": 74, "similar_positions": 38, "identity": "42.05%" }, { "cls_id": "homologset.agr.HGNC:34442", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTJ8-1", "uniprot_id": "D3ZTJ8_RAT", "id": "D3ZTJ8-1", "name": "", "aln": "MGTSLRSQSFREPRPCYGRLHESHGRSLEGRLRRALSLRQGREKSRSQGPN-GSEGLEVSVQERLPGTLGDTEQLIQTQRGG-SRRWLRQYQQ-VKRRWRSFVASFPSVTLSQPASPEALLDTNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC23-1", "uniprot_id": "CK086_MOUSE", "id": "Q8VC23-1", "name": "Uncharacterized protein C11orf86 homolog", "aln": "MGTSLRSQSFREPRPSYGRLHESQGRSLDGRLHRALSLRLGREKSRSQVPD-GTEGLEVSVQERLPGTLGDKEQLIQGQRGGGSRRWLRQYQQHVKRRWRSFVASFPSVTLSQPASPETLLDTNN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJI1-1", "uniprot_id": "CK086_HUMAN", "id": "A6NJI1-1", "name": "Uncharacterized protein C11orf86", "aln": "MGTGLRSQSLREPRPSYGKLQEPWGRPQEGQLRRALSLRQGQEKSRSQGLERGTEGPDATAQERVPGSLGDTEQLIQAQRRG-SRWWLRRYQQ-VRRRWESFVAIFPSVTLSQPASP--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*****:*****.**:*:*. **. :*:*:****** *:****** : *:** :.:.***:**:***.***** ** * ** ***:*** *:***.**** ************ ", "identical_positions": 81, "similar_positions": 23, "identity": "64.8%" }, { "cls_id": "homologset.agr.HGNC:34443", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M7U7-1", "uniprot_id": "VSTM5_RAT", "id": "Q5M7U7-1", "name": "V-set and transmembrane domain-containing protein 5", "aln": "MRPPRCVGR-TQGIPLGLLAFWVATARCLQSQGVSLYIPRSAINATVQEDILLSVDYICHGVPTIEWEYTPNWGVQKIVEWKPGTPANVSQSHRDRVCTFDNGSIQLFSVGVRDSGYYVITVTEHPGSSQSGTILLHVSEIRYEDLHFVAVFFALLAAVAVVLISLMWVCNQCAYKFQRKRRYKLRESTTEEIEMKDVEC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D806-1", "uniprot_id": "VSTM5_MOUSE", "id": "Q9D806-1", "name": "V-set and transmembrane domain-containing protein 5", "aln": "MRPLRCGER-TQGIPLGLLAFWVTAARCLQSQGVSLYIPQSAINATVQQDILLSVDYICHGVPTIEWKYTPNWGVQRIVEWKPGTPANVSQSHRDRVCTFDNGSIQLFNVSVKDSGYYIVTVTEHPGSSQSGTILLRVSEIRYEDLHFVAVFFALLAAVAVVLISLMWVCNQCAYKFQRKRRYKLKESTTEEIEMKEVEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MXK1-1", "uniprot_id": "VSTM5_HUMAN", "id": "A8MXK1-1", "name": "V-set and transmembrane domain-containing protein 5", "aln": "MRPLPSGRRKTRGISLGLFALCLAAARCLQSQGVSLYIPQATINATVKEDILLSVEYSCHGVPTIEWTYSSNWGTQKIVEWKPGTQANISQSHKDRVCTFDNGSIQLFSVGVRDSGYYVITVTERLGSSQFGTIVLHVSEILYEDLHFVAVILAFLAAVAAVLISLMWVCNKCAYKFQRKRRHKLKESTTEEIELEDVEC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** . * *:**.***:*: :::**************:::*****::******:* ********* *:.***.*:******** **:****:**************.*.*:*****::****: **** ***:*:**** *********::*:*****.**********:**********:**:********:::***", "identical_positions": 150, "similar_positions": 38, "identity": "75.0%" }, { "cls_id": "homologset.agr.HGNC:34444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0Z9-1", "uniprot_id": "D4A0Z9_RAT", "id": "D4A0Z9-1", "name": "", "aln": "MPKGRRGSQNPKMSQRPAPPLYFPSLYDRGISSSPLSDFNIWKKLFVPLKAGGTPSAGVAGVAGVRPLPLAPPATVPPPPPGLGPPSERPCPPPWPSGLASIPYEPLRFFYSPPPGPEMATSALVPGSTTPWLASASHPEELCELEIRIKELELLTITGDGFDSQRYKFLKALKDEKLQGLKTTRQPGK-SASFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1Z2-1", "uniprot_id": "CK091_MOUSE", "id": "Q9D1Z2-1", "name": "Uncharacterized protein C11orf91 homolog", "aln": "MPKGRRGSQNPKMSQRPAPPLYFPSLYDRGISSSPLSDFNIWKKLFVPLKAGGTPAAGVAGVAGVRSLPLAPPATVPPPPPGLGPPSERPCPPPWPSGLASIPYEPLRFFYSPPPGPEMATSALVPGSTTPWLASASHPEELCELEIRIKELELLTITGDGFDSQRYKFLKALKDEKLQGLKMSRQPGK-SASCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3C1V1-1", "uniprot_id": "CK091_HUMAN", "id": "Q3C1V1-1", "name": "Uncharacterized protein C11orf91", "aln": "MPKGRRGSHSPTMSQRSAPPLYFPSLYDRGISSSPLSDFNIWKKLFVPLKAGGAPVGGAAGARSLS-QALPAPAPPPPPPPGLGPSSERPWPSPWPSGLASIPYEPLRFFYSPPPGPEVVASPLVPCPSTPRLASASHPEELCELEIRIKELELLTITGDGFDSQSYTFLKALKDEKLQGLKT-KQPGKKSASLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:.*.****.************************************:* .*.**. .: .*..**. *********.**** *.*************************:.:*.*** .:** ********************************* *.************** :**** *** *", "identical_positions": 157, "similar_positions": 24, "identity": "80.51%" }, { "cls_id": "homologset.agr.HGNC:34447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97590-1", "uniprot_id": "LEG7_RAT", "id": "P97590-1", "name": "Galectin-7", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSATHHKTPLPQGVRLGTVMRIRGVVPDQAGRFHVNLLCGEEQE----ADAALHFNPRLDTSEVVFNTKQQGKWGREERGTGIPFQ--RGQPFEVLIITTEEGFKTVIGDDEYLHFHHRMPSSNVRSVEVGGDVQLHSVKIF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54974-1", "uniprot_id": "LEG7_MOUSE", "id": "O54974-1", "name": "Galectin-7", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSATHHKTSLPQGVRVGTVMRIRGLVPDQAGRFHVNLLCGEEQG----ADAALHFNPRLDTSEVVFNTKQQGKWGREERGTGIPFQ--RGQPFEVLLIATEEGFKAVVGDDEYLHFHHRLPPARVRLVEVGGDVQLHSLNIF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47929-1", "uniprot_id": "LEG7_HUMAN", "id": "P47929-1", "name": "Galectin-7", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQG----SDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQ--RGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPI6-1", "uniprot_id": "Q9VPI6_DROME", "id": "Q9VPI6-1", "name": "Galectin", "aln": "MTAIILLACHSVRELVDLSDALWQNTFNIERSLNYYRIKRRLELFRFHCRELWLRQVSKTSDPMHRKAGIDFAAIEAGADCVLNMDAFDDTTTELHKRFLQAEGTRPFPSDCISGIEVVDGNEFKASFYEYADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNNDS-----RDVALHINPRLPQNYIVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVKGDVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNTQSDSSPKRNNSSNDLGLTLPYYG-ALPPNSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYKVSPEVVDTVYIQGDVKLWNVTLEKNQMIKGKNMRVYQN----PWFFSE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPI7-1", "uniprot_id": "Q9VPI7_DROME", "id": "Q9VPI7-1", "name": "Galectin", "aln": "------------------------------------------------------------------------------------MSVYPGACTVALRRVMDAMS---------------------LFYEKRSEAHRRKHFKVIQCPRPGLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQNYITRNSRLKGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYVSEYPIRLTHS--------LPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKFLYQPS-----LPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLFHFKYQMRPECVDIVNIRGDIKLWEVAIQGNTTYKKPKVRSAMERAISAWKRAEIPQLQI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . * : . :* :::: : . *. *::..** . :. *:: :. ** ** .. :.* **: * : :: :: : :.. .: : **:* :. ::* ***. : ", "identical_positions": 23, "similar_positions": 48, "identity": "4.43%" }, { "cls_id": "homologset.agr.HGNC:34448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJL6-1", "uniprot_id": "A0ABK0LJL6_RAT", "id": "A0ABK0LJL6-1", "name": "", "aln": "MDANQSTDVSALTLATLSEDMTSLQMRTDGKEHQLTEESSDFLQNVSVTEGA-----KEVAEMDHISDRPDEKEKLS-ENLQTDVLYKMDTKKWDGLEEESQHREDPPSKQDEREVTPVCEVPQASPRPPSSDE--STPIPDSLVVKLNYWHEKMGLQMKELGAHHVDWLERINNIIQNINSTESTVKSLLTEVISLENQSKNLEDPDQEADIEEKIVEIRRQLKEVNIKLNQVDACKEARELKEKLVERIESFHKEINVLNTKLEMHYKQGSETDSHSSEDVAMEHEEPFILEASPSPSGSPSPPCSAVWKHAVKLLVMVYVVTITGLSCYILFVDATFLFERVLPSVLGHRTMWDLREMMAPFLNLEAEDLLPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DA21-1", "uniprot_id": "SMCO2_MOUSE", "id": "Q9DA21-1", "name": "Single-pass membrane and coiled-coil domain-containing protein 2", "aln": "--------------------MMSLQLGTAGKERQLAEKSRD-LQNVSMTEGS-----EEVSEMDHISDRPDEKDKPS-ENLQTDSLYKMDTEKWDGLEQESEHSQDPPSKPDEQEVTLVCEGPQVSQLSPSTDE--STPIPESLTHKLNYWHAKMGLQMKELGADHGDWLERINNIIQNINNTESTVKSLLTEVISLENQSKNLEDSDQEADIEEKITEIRRQLKEVNIKLTQVDACEEARELKEKLVEQIESFHKEMNVLNSKLEMYYTQGSDADSHNSEDVDTEQEEPLVPEASPSLSASPTPPCSAVWKNALKLFVIVYVVTITGLSCYILFVDATFLFERVLPSVLGHRTMWDLREMMAPFLNLEAEDLLPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFE2-1", "uniprot_id": "SMCO2_HUMAN", "id": "A6NFE2-1", "name": "Single-pass membrane and coiled-coil domain-containing protein 2", "aln": "---------MALTPTNLNN-KMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKG------MLELEAEHDQD-LSKQDKQE-TDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLED---------------RGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTAWKRALRIFIMFDVLTVTGLLCYILFFGATFLFERVLLRMLGCRTTWDLREMREPFLNLEVEALLPS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: :*:**:::. . :*::.:***: :*: ::*** **.*:::. * ** *** *:* ** *::* :* ** *::* * * * **.* :.: ..: *****: *:***:*****.: * *:*:***::** **.******.::::*:.* ::*** * *. : . .:*::*:*. ***:*::*::*.: *::::*.:**.*: :..::***.**:: *. *.:: :*..* . :** .:.**.*::::::. *:*:*** *****..********* :** ** ****** ******.* ****", "identical_positions": 145, "similar_positions": 113, "identity": "38.56%" }, { "cls_id": "homologset.agr.HGNC:34450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZG3-1", "uniprot_id": "D3ZZG3_RAT", "id": "D3ZZG3-1", "name": "", "aln": "MPGGVPWSVYLKMLSSSLLAMCAGAQVVHWYYRPDLTIPEIPPKPGELRTELLGLRERHRESQVSQQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTC1-1", "uniprot_id": "UQCC6_MOUSE", "id": "Q8BTC1-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "aln": "MPGGVPWSAYLKMLSSSLLAMCAGAQVVHWYYRPDLTIPEIPPKPGELKTELLGLKERRHEPHVSQQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69YU5-1", "uniprot_id": "UQCC6_HUMAN", "id": "Q69YU5-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "aln": "MPAGVPMSTYLKMFAASLLAMCAGAEVVHRYYRPDLTIPEIPPKRGELKTELLGLKERKHKPQVSQQEELK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXZ6-1", "uniprot_id": "UQCC6_DANRE", "id": "E7EXZ6-1", "name": "Ubiquinol-cytochrome-c reductase complex assembly factor 6", "aln": "MPAGVSWPRYLRMFAASVLSMFAGAQVVHHYYRPDLSIPEIPPKPGELRTELLGLKERQMDSQKQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0X7-1", "uniprot_id": "UQCC6_DROME", "id": "B7Z0X7-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "aln": "MPAGVSWGQYLKFLGCALASMMAGSQAVHLYYKPLEDLRVYIEQ--EQHSTQVDPTAKPPESA--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.**. **:::..:: :* **::.** **:* : : * :: :. : .. ", "identical_positions": 15, "similar_positions": 23, "identity": "21.13%" }, { "cls_id": "homologset.agr.HGNC:34452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H53-1", "uniprot_id": "CL071_RAT", "id": "Q66H53-1", "name": "Uncharacterized protein C12orf71 homolog", "aln": "MTTSASSSDYSNTEDCISECKSNQSASVGYYPSENTFSYEDVVSPEEAASVESSAHFLPPVQGSWGTESLRRLFRKRDQMKHDPEQFCKLSITLAWDIDVGSDRADSLANLDLNSHSQWMNKWPEDRTKLTPYKLDNLVRKLETFLGKEKGGQHDSHVLPESTQKEDVFLNSSPPPHTAQVSHHEHDACQDLPKHKALENEDICQAPENPPRLLKDEVV-EISQADGSSLETSSMSSPRPED---ASHLHRTSCMNFQWVFHWLRTQVS-SRWRREHPSQAPVSWHQKAMRRMHSFRGNRIQPQE--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W69-1", "uniprot_id": "CL071_MOUSE", "id": "Q80W69-1", "name": "Uncharacterized protein C12orf71 homolog", "aln": "MTTSPSSSDYSSTEDSIYECKSNQSASVGYYPSENTFSYEDLVSREETASVDSLVHFLPPVQSTWRTESLRRLFRKRDQVEHDPEQFSKLSITLAWDIDVDSNHADSLANLDLNAHSQWMDKWPEDKTKLTPCKLYNLVQKLETFLGKEKGGQHDGCVLPESTQKEDVHLNSTTPPHTAQVSPKERDVCQDLSKQRSLENEDICQVLEDPPRLLKDEVVQEIRQASESSLETSSVSSPQPEG---ASRSHNIFCMNFRWVFQWLRTQIF-SRWRRQRPSQATNTWHQKAVRNIHSLRSNRIQPQE--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MTZ7-1", "uniprot_id": "CL071_HUMAN", "id": "A8MTZ7-1", "name": "Uncharacterized protein C12orf71", "aln": "MAYSSSNSD---IEDDSSKSNSNLSLSVGYFPCEDTP-CEDTTSWEDAPSKGPSIHFLPPVQGAWGTERIGRRMKRQDQIQDEPEQFCKLSIFLAWDVDIGSDNTDSRANRLLNGDNLWIDKLPKERTKLSVGKLNNLVQEFQIFLENLK---DDDAVFPETAQ-QDFQLSSGSPPEMVQMIS------QATASQR------------------------------TSAPEISSILSEQPEKDDTPSHTQAQCCLNFGWAFSWLRQRILPSLLRRDHPVNATKSPHRSAPTKRLFHRGKRIQPQETLELGHPI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *.*.** ** :.:** * ****:*.*:* ** .* *::.* . *******.:* ** : * ::::**::.:****.**** ****:*:.*:.:** ** **... *::* *:::***: ** ***:::: ** : * .*. *:**::* :*. *.* .**. .*: * ..:: *: * **: * :** .*: : *:** *.* *** :: * **::* :*. : *:.* . *.:****** ", "identical_positions": 111, "similar_positions": 82, "identity": "35.46%" }, { "cls_id": "homologset.agr.HGNC:34453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NNL5-1", "uniprot_id": "CO061_HUMAN", "id": "A6NNL5-1", "name": "Uncharacterized protein C15orf61", "aln": "MEALRRAHEVALRLLLCRPWASRAAARPKPSASEVLTRHLLQRRLPHWTSFCVPYSAVRNDQFGLSHFNWPVQ-GANYHVLRTGCFPFIKYHCSKAPWQDLARQNRFFTALKVVNLGIPTLLYGLGSWLFARVTETVHTSYGPIT-VYFLNKEDEGAMY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VG49-1", "uniprot_id": "CO061_MOUSE", "id": "Q0VG49-1", "name": "Uncharacterized protein C15orf61 homolog", "aln": "MEALRRAHEATLRLLLCRPWASGAASRPKPRASEVLTQHLLQRRLPHWTSFCVPYSAVHNDQFGLSHFNWPVL-GANYHVLRTGCFPFIKYHCSKAPWQDLAPQDRFFTALKVINLGIPTLLYGLGSWLFARVTETVHTSYGPIT-IYFLNKEDEGAMY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LKW0-1", "uniprot_id": "A0ABK0LKW0_RAT", "id": "A0ABK0LKW0-1", "name": "", "aln": "MEPLRRAHEAMLRLLLWGPWASGAASRPKPRASEVLTRHLLQRRLPHWTSFCVPYSAVHNDQFGLSHFNWPVP-GANYHVLRTGCFPFIKYHCSKAPWQDLAAQNRFFTALKVINMG--EWRPDRGTLPAQGGRWPTSTPLGFQG-QFFASP--PGCLQHP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4V381-1", "uniprot_id": "A4V381_DROME", "id": "A4V381-1", "name": "", "aln": "MQLTR--------LLL------------KPRASEVLTAYLKQCHEPPWTSYFVKFHDVANDQRGMSHFNWTLENGTNYHILRTACYPYMKYHCSKREVQDLWLEDKFFRFLKVINLGLPMLFYGLAAIRLISHTEIVHVSETVKVPIYFLYPEDKGSSF--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * *** ** ****** :* * : * ***: * : * *** *:*****.: *:***:***.*:*::****** *** :::** ***:*:* . .: . .. :* *. ", "identical_positions": 57, "similar_positions": 27, "identity": "35.4%" }, { "cls_id": "homologset.agr.HGNC:34454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M154-1", "uniprot_id": "F1M154_RAT", "id": "F1M154-1", "name": "", "aln": "MSEPAD-GPSLGLSPPQLSTVTLEDLELLLTEGLASHEPSSTESL-EKYECSGLVSNSLVPEQDTPKQWKQLEQWVAELQAEVVRLRGHKERCEHATLGLLQELLQVHARVQMQASELRQLRQEVQQAAWSPEKEELELSGPQSQDQMQALDKRLVEVREALTHIRRKQALQDSERRHAEQEINLRLTNLTAMLSQEEQGREAACSALQKNQEDTSQKVDLESAKMQAQMMKLNEEISLRFLKREAKLCGFLQKTFMVLEQRMKSSETARLSAESSLREELETRWQKLHELTEESLRVLRAQREEEEGHLLEQCRGLDKAVVYLTKFVQQNQVSLNRVLMAEQKAREAKVSLEETQAEELASYVHENLEAVQMAGKLAQQETQDALELLQEKSQVLEGSVAGLDQQLKDLSDHCLALSWRLDLQEQTLGLKLFQAQAAWEGVERESLQDLAQWLTEVSAHLQEVQERVSSLPQQIESVSNKCVLYKSDVDVKISAEGKAREFEVETVRQELAALLMSVQLLKEENPGRKIAEIQGQLATFQKQMIKLENSLQANKTIQNLKFNNETKLRTEEIATLRESMLHLWSEEGPWPLTLGSKRVFMSLVRQRFFIKDVALGELVPVNSWGVYQAVRWLHWKTVLLNLVTQKRPGVNSAMTQCRPASRSHL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6RUT8-3", "uniprot_id": "CC154_MOUSE", "id": "Q6RUT8-3", "name": "Coiled-coil domain-containing protein 154", "aln": "MSEPAD-GPSLRLSPSHLSTVTLEDLELLLTEGLVSAETS------ERDECSGRASGSLVPEQDTSKLWKQLEQWVAELQAEVVRLRGHKERCEHATLGLLRELLQVRARVQMQASELRQLRQVVQQAAWSPEKEELELSGPQSQNQMQTLDKRLVEVREALTHIRRKQALQDSERKHSEQEINLRLTNLTGMLSQEEQGREAACSALQKNQEDTSQKVDLGLAKMQAQMTKLNEEMSLRFLKREAKLCSFLQKSFLALEQRMKSSESTRQIAESSLREELESRWQKLHELTEERLRALRAQREEEEGHLLEQCRGLDKAVVYLTKFVRQNQVSLNRVLMAEQKAREAKVSLEETQAGELASYVHENLEAVQMAGKLAQQETQDALELLQEKSQVLEGSVAGLDQQLKDLSDHCLALSWRLDLQEQTLGLKLSQKQAAWEGMERESLKDLVQWLKEVTAHLEEVQEKVNSLPQQIESISNKCVIHKSEVDVKISAEGKAREFEVETVRQELAALLMSVQLLKEENPGRKIAEIQGQLATFQKQMIKLENSLQANKTIQNLKFNNETKLRTEEIATLRESMLRLWSEEGPWPLTLGSKRVFMSLVRQRFFIKDVALDAMVSVNSWGVYQAVRWLRWKRFLLNLVAQKRPGVTSAMTQWKPAYEVTSLTVFQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NI56-1", "uniprot_id": "CC154_HUMAN", "id": "A6NI56-1", "name": "Coiled-coil domain-containing protein 154", "aln": "MSELADSGPSGASAPSQLRAVTLEDLGLLLAGGLASPEPLSLEELSERYESSHPTSTASVPEQDTAKHWNQLEQWVVELQAEVACLREHKQRCERATRSLLRELLQVRARVQLQGSELRQLQQEARPAAQAPEKEAPEFSG--LQNQMQALDKRLVEVREALTRLRRRQVQQEAERRGAEQEAGLRLAKLTDLLQQEEQGREVACGALQKNQEDSSRRVDLEVARMQAQVTKLGEEVSLRFLKREAKLCGFLQKSFLALEKRMKASESSRLKLEGSLRGELESRWEKLRGLMEERLRALQGQHEES--HLLEQCQGLDAAVAQLTKFVQQNQASLNRVLLAEEKAWDAKGRLEESRAGELAAYVQENLEAAQLAGELARQEMHGELVLLREKSRALEASVAQLAGQLKELSGHLPALSSRLDLQEQMLGLRLSEAKTEWEGAERKSLEDLARWRKEVTEHLRGVREKVDGLPQQIESVSDKCLLHKSDSDLRISAEGKAREFKVGALRQELATLLSSVQLLKEDNPGRKIAEMQGKLATFQNQIMKLENCVQANKTIQNLRFNTEARLRTQEMATLWESVLRLWSEEGPR-TPLGSWKALPSLVRPRVFIKDMAPGKVVPMNCWGVYQAVRWLRWKASLIKLRALRRPGGVLEKPHSQEQVQQLTPSLFIQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** *** :*.:* :****** ***: **.* *. *: *.* .* : ******.* *:******.******. ** **:***:** .**:*****:****:*.******:* .: ** :**** *:** *:***:*************::**:*. *::**: :*** .***::** :*.*******.**.********:*::*** *:****: **.**:************.****:*:.**:***:**::* *.*** ***:**:**: * ** **.*:.*:**. ******:*** **. *****:***.******:**:** :** ***::* ***:**:*****.*:**:**:** :. * **:***:.**.*** * ***:**.* *** ******* ***:* : :: *** **:**:**.:* .**: **. *:*:*..*******:*:**:::**: *::**********:* ::*****:** *******:********:**:*****:*::****.:*********:**.*::***:*:*** **:*:******* .*** :.: **** *.****:* . :*.:*.**********:** *::* : :*** .: : . ", "identical_positions": 411, "similar_positions": 154, "identity": "61.16%" }, { "cls_id": "homologset.agr.HGNC:34455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M3A2-1", "uniprot_id": "F1M3A2_RAT", "id": "F1M3A2-1", "name": "", "aln": "MEALVCAFSELRIREDAVSWAPGRPSHPDTPPNIYEGGLGAQQQQGPSAQGSKPKNFRLRHLRSLALYLPGHMQPAGQCGSHWLGRLMAGGSLTRPEGSPWPLALPQGTLGPGNGHCSALLEARLPRDSLGNTASSSSMDPAKGVPSQSGPPEGLGLRPKRSWRALEETMCPLCKRTRSGALERT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BT88-1", "uniprot_id": "CP090_MOUSE", "id": "Q8BT88-1", "name": "Uncharacterized protein C16orf90 homolog", "aln": "--------------MDAVSWAPGRPSHPDTPPNIYEGGLGAQQQQGPSAQGSKPKNFRLRHLRSLALYLPGHMQPAGQCGSHWLGRLMAGGSLTRPEGSPWPLDLPQGTLGPGNSHCSALLEAHLPRDSLGNTASSSSMDPAKGVPSQSGPPEGLGLRPKRSWRALEETMCPLCKRTRSGALERT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MZG2-1", "uniprot_id": "CP090_HUMAN", "id": "A8MZG2-1", "name": "Uncharacterized protein C16orf90", "aln": "MEALVCAFSELHIREDAVSQAQGRPGHPDAPPNIYEGGLGSPQPQCPSAQGSKPKNFRLRHLRGLGLYLESHPPPTGQCESHWLGRLMAGGCLPQPEGTAWALDLPQGTLGPRNSLCSALLEARLPRDSLGSSASSSSMDPDKGALPQPSPSR---LRPKRSWGTWEEAMCPLCKRTRSGALERP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** * ***.***:**********: * * *****************.*.*** .* *:*** ***********.*.:***:.*.* ******** *. *******:*******.:******** **. .*..*.. ******* : **:***************.", "identical_positions": 125, "similar_positions": 26, "identity": "67.57%" }, { "cls_id": "homologset.agr.HGNC:3446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11308-4", "uniprot_id": "ERG_HUMAN", "id": "P11308-4", "name": "Transcriptional regulator ERG", "aln": "-------------MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVP-ADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNP-YWNSPTGGIYP---NTRLPTSHMPSHLGTYY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A3D6-1", "uniprot_id": "D4A3D6_RAT", "id": "D4A3D6-1", "name": "", "aln": "------MIQTVPDPEAQIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVTKGGKMVGSPDTVGMSYGSYMEEKHMPPPNMTTNERRVIVP-ADPTLWSTDHVRQWLEWAVKEYGLLDVDVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSTWTGHSHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHTHPQKMNFVAPHPPALPVTSSSFFATPNP-YWNSPTGGIYP---NTRLPASHMPSHLGTYY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81270-1", "uniprot_id": "ERG_MOUSE", "id": "P81270-1", "name": "Transcriptional regulator ERG", "aln": "------MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQAPARVTIKMECNPSQVNGSRNSPDECSVNKGGKMVGSPDTVGMSYGSYMEEKHVPPPNMTTNERRVIVP-ADPTLWSTDHVRQWLEWAVKEYGLLDVDVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHSHLTPQSKAAQPSPSAVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVSPHPPALPVTSSSFFASPNP-YWNSPTGGIYP---NTRLPASHMPSHLGTYY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29774-1", "uniprot_id": "ETS3_DROME", "id": "P29774-1", "name": "DNA-binding protein D-ETS-3", "aln": "MYENSCSYQTALDLKRVSPPTLAQVKTEECLALGQC-SPEWTSYRFHQSTFEQLKQSVEKAKAALQ-DRSSFFGASSAFSDIYSSQRLTDSLDTLPVQSGNGGGNCLGLPHNPNVGVGVAGVLNYNAVSSSTAGVLSSSGNGVQRHRLDTLQPPSGCSPAVTQHGVITSSAGQVT--SGTLDAVSAAPALPSLTASS--SSHVEHKVRADKSTLDCATTSSHAAAPSSSSSASDHQQGRISGSKSSNTSGTGGGASASGGGGSALYSS-YKSSWGSHSSTQSQGYSSN-ALGIKHDPHSQLRQPDPYQMFGPTSSRLASSGSGQIQLWQFLLELLSDSNNASCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGLAAATQPAASDP-TYKYQSDL-FMTPYHHSAKLSSFMSPHHGMTSSSASIFPSAASWGNWGSPATNLYQPHSMSHVTPSHVAPHLSSYPHYA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *. ::.* :*. :. .: *: .: *: : : . * * * * ::. ...::..* :: * **: :* *.. .:. * :: . .. *:. .: .* : . . **.::*: . . .*. . : : **.* . :.* ::.* *:.. * ..*. . :: :. .*** .:. . *.. :*:* .*. .*. ::: : . ....* * ****::********..******************.*:.************:***************************************************:*:* * ** ..:. *** *** :* .** .: .*::** . ::* * ::.. *.**: .:* :::..**:..**.:* ", "identical_positions": 163, "similar_positions": 144, "identity": "32.6%" }, { "cls_id": "homologset.agr.HGNC:3447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q98874-1", "uniprot_id": "ERH_DANRE", "id": "Q98874-1", "name": "Enhancer of rudimentary homolog", "aln": "---------------------------------MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFVDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6GLN9-1", "uniprot_id": "A0A8I6GLN9_RAT", "id": "A0A8I6GLN9-1", "name": "Enhancer of rudimentary homolog", "aln": "--------------CCAQVREDIRIFIEVVFPLQSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84089-1", "uniprot_id": "ERH_MOUSE", "id": "P84089-1", "name": "Enhancer of rudimentary homolog", "aln": "---------------------------------MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84090-1", "uniprot_id": "ERH_HUMAN", "id": "P84090-1", "name": "Enhancer of rudimentary homolog", "aln": "---------------------------------MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24337-1", "uniprot_id": "ER_DROME", "id": "Q24337-1", "name": "Protein enhancer of rudimentary", "aln": "---------------------------------MSHTILLVQPGARPETRTYCDYESVNECMEGVCKIYEEHLKRRNPNTPTITYDISQLFDFIDTMVDISCMVYQKSTNTYAPYNKDWIKEKIYVLLRQAAFSSNT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4A5C2-1", "uniprot_id": "D4A5C2_RAT", "id": "D4A5C2-1", "name": "Enhancer of rudimentary homolog", "aln": "MLHQLSRDLLLEALLLSACVVWFRLDCRLAFAAMTPIKLLVQPTQRPEGRTYAEYGSVNECMEGICKMYEEHLKRLNPLSQSITYGVSQLFEFIDRMVDLSCLVFREDTQTYKPHSREWVKERIYMLLSQQAQRDESE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***** *** ***.:* ********:**:******* ** : :***.:****:*:* :.*:**:*:: .*:** *:.::*:**:**:** : * . ", "identical_positions": 56, "similar_positions": 28, "identity": "40.58%" }, { "cls_id": "homologset.agr.HGNC:34489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CE97-1", "uniprot_id": "CO062_MOUSE", "id": "Q8CE97-1", "name": "Uncharacterized protein C15orf62 homolog, mitochondrial", "aln": "------METWRKGSFRNASFFKRITLGRPRRLHRQGSILSQASTAGGDHEEYSNREVIRELQGRPDGRRLPLWGDEHPRATLLAPPKPPRLYRESSSCPNILEPPASYTAGYSATLPSAISLTGPLHQCSEEALSDTPHFPRTPTPDLSDPFLSFKVDLGLSLLEEVLQILKEQFPSEPHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A1S9-1", "uniprot_id": "A0A8I6A1S9_RAT", "id": "A0A8I6A1S9-1", "name": "", "aln": "MTLRNSMETWRKGSFRNASFFKRITLGRPRRLQRQGSVLSQASTAGGDHEEYSNREVIRELRGRPDGRRLPLWGDEHPRATLLAPPKPPRLYRESSSCPNILEPPATYTTAYSATLPSAISLTGPLHQCSEEGLLDTPHFPRTPTPDLSDPFFSFKVDLGLSLLEEVLQILKEQFPSEPHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8K5M9-1", "uniprot_id": "CO062_HUMAN", "id": "A8K5M9-1", "name": "Uncharacterized protein C15orf62, mitochondrial", "aln": "------METWRKGSFRNASFFKQLSLGRPRRLRRQSSVLSQASTAGGDHEEYSNREVIRELQGRPDGRRLPLWGDEQPRATLLAPPKPPRLYRESSSCPNILEPPPAYTAAYSATLPSALSLSSALHQHSEKGLVDTPCFQRTPTPDLSDPFLSFKVDLGISLLEEVLQMLREQFPSEPSF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****************:::*******:**.*:***********************:**************:****************************.:**:.********:**:..*** **:.* *** * ***********:*******:********:*:******* *", "identical_positions": 148, "similar_positions": 22, "identity": "81.77%" }, { "cls_id": "homologset.agr.HGNC:3449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQY0-1", "uniprot_id": "ERN1_MOUSE", "id": "Q9EQY0-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "-------MPARWLLLLLALLLPPPGPGSFG---------------------------------------------------------------------RTSTVTLP--------------ETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVE--EPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTGEKQ--------------QTLSSAFADSLCPSTS--LLYLGRTEYTITMYDTKTRE---LRWNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQGEVLRKVVHINVAVETLR--YLTFMSGEVG-RITKWKYPFPKETE-AKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINIVGQTSDNTPTTVSQDVEEKLARAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSVHQQRQLQHQQFQKELEK-IQLLQQQQ--LPFHPHGDLTQDPEFLDSSGPFSESSGTSSPSPSPRASNHSLHPSSSASRAGTSPSLEQDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF----AHLG--LEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPN--------AHGRIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSEDC----------------------------KDNPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACNLDCFHSDKHED----VIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKEALDGPIVRQLERGGR---AVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPHLLSHTYQAMELCRHERLFQTYYWH-------------------------EPTEPQPPV--------IPYAL------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K2H4-1", "uniprot_id": "A0A0G2K2H4_RAT", "id": "A0A0G2K2H4-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "-------MPARWLLLLLALLLLPPGPGSFG---------------------------------------------------------------------RASTVTLP--------------EALLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVE--EPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTGEKQ--------------QTLSSAFADSLCPSTS--LLYLGRTEYTITMYDTKTRE---LRWNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAVETLR--YLTFMSGEVG-RITKWKYPFPKETE-AKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENTPTTVSQDVEEKLPRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQFQKELEK-IQLLQQQQ--LPFHPHGDLTQDPDFLDSSGLFSESSGTSSPSPSPRASNHSLNSSSSASKAGTSPSLEPDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF----AHLG--LEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPN--------AHGRIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSEDC----------------------------KENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACSLDCFHSDKHED----VIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVRQLERGGR---AVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKRHHYRELPLEVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCRHERLFQTYYWH-------------------------EPTEAQPPG--------IPDAL------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75460-1", "uniprot_id": "ERN1_HUMAN", "id": "O75460-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "-------MPARRLLLLLTLLLP--GLGIFG---------------------------------------------------------------------STSTVTLP--------------ETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVE--EPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTGEKQ--------------QTLSSAFADSLCPSTS--LLYLGRTEYTITMYDTKTRE---LRWNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLR--YLTFMSGEVG-RITKWKYPFPKETE-AKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEK-IQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPSTSPRASNHSLCSGSSASKAGSSPSLEQDDGDEETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF----AHLG--LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPN--------AHGKIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSEDC----------------------------KENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHED----VIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGR---AVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFH-------------------------EPPEPQPPV--------TPDAL------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8S4-1", "uniprot_id": "A0AB13A8S4_DANRE", "id": "A0AB13A8S4-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MAWGVCSRALVWIITALIWWSHSGLMGFC-------------------------------------------------------------------SSSTVSVP--------------ESLLFVSTLDGNLHAVSKISGTIKWTLKEDP-----VLQVPTHVS--EPAFLPDPNDGSLYSLGGKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDVWYVVDLLTGEKK--------------QTLTSSYAEMLCPSSS--LFYLGRTEYTITMYDTKSRE---LRWNATYSDY-AFTLPDED-TKYNMAHFVSNGDGLVVTVDSESGDVQWVQNYNSPVVAVYIWQREGLRKVPHTNVAVETLR--YLTFMSGEVG-RITQWKYPFPREKK-TKDKLLSTLYVGKHSSGLYASPSLVHDGVTVVPRGRTFPMLEGPGNQGSREED-EQECVITPSTTVNFNAALKERNRINFMRNSLLLIGHHEMPPDAHHKFLEKFPESIPRQNMNVIPPATEK-TIEEKVNESGMEDNSPLPPPVSSLQEKPGRVP-RVETPVDSMLKDMATIIFCTFLLAGWVAFVITYPKSVHKQQQLQHQQFQQQMEEKLQLLQRQQ--LIFQPPTDLPPDSDFLEAARTRSESSTHSSPNGTPRASNHSNISQCETGHSAN----EHEDTEEESNIVRIGNITFNPKNVLGHGAEGTIVYRGQFDNRPVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCNSTLQEYVERKDF----NRHG--LEPVTLLEQTMSGLAHLHSLNIVHRDLKPHNILVSMPN--------MHGRVKAMISDFGLCKKLAVGRHSFSRKSGVP-GTEGWIAPEVLSEDA----------------------------KHNPTCMVDIFSAGCVFYYVVSEGFHPFGKSLQRQANILLGAYSLDHLDPNRHES----IVARNLIEQMLNMEPEKRPSADRVLKHPFFWSLEKQLHFFQDVSDRIEKEPLDGPIVRQLERGGR---VVVKGDWRDHITVPLQTDLRKFRSYKGGSVRDLLRAMRNKKHHYRELPEDVQQTLGTIPDEFVFYFTSRFPLLLQHTHLAMRYCAVERSFLPYYHVSELLAHHTIMQCVPQTSSTQHSCASEPSGLSSSSQISESLHELPDALS-------------EMAAPSEHTQTGPEKTGAP---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1QQI8-1", "uniprot_id": "A0A8M1QQI8_DANRE", "id": "A0A8M1QQI8-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "-------MMRMMKNWTQMLLLLVCFAGIVSQCE------------------------------------------------------------------GGSSVSLP--------------ESLLFVSTLDGSLHAVSKQTGDIKWTLKEDP-----IIQVPEYFQ--EPGFLPDPNDGSLYVLGGKRKEGLMKLPFTIQELVQSSPCRSS-------------DGVLYTGKKQDTWFVVDPQTGEKQ--------------TSLSTSSSDSICPSAP--LLYIGRTEYMITMYDTKTQE---LRWNATYNDY-SAPLYDDKKYEYKMSHFASSGDGLVVTVDRDSGEVLWMQKFDSPVAGFYLWSQDSLRRAPHLTVATETLR--YLTFTAENTQSHTMKWTYQFTKESHSTKTQLVPTLYVGKTESHLYASASLVHQGVAIVPKGLTLARIEGPMTAGVTMGNGRPECEITPSTDVKYPPGSSSS-----LQNQWLLIGHHEIPPLAHTTMLRDFPENLQR-SGDVIPP---------------RGSGSSYRSPSHPLP--PVRKQSSSPVLPDSLSSEPMTVLVVTLLLGAWITFLLTHKWPVKKSQRSEEPVDSTPLSG----------------LTNYSASTELNTPPSTSSYSNSSRSEKTSSVASNQTQPFSSKDSAPVT---AASQSQNEQADVVEVGKISFSPAEVLGHGTEGTFVFRGHFDGRRVAVKRILPECVEFAEREVQLLRESDEHPNVIRYFCTERDRQFTYIAIELCAATLQQYVEDPSC----PHSE--LNPVSLLEQTMCGLSHLHSLNIVHRDLKPRNILLSLPG--------ALGRVRALISDFGLCKKLPDGRHSFSLRSGIP-GTEGWIAPELLINAP----------------------------KGNPTSAVDIFSAGCVFYYVTSKGQHPFGDTLRRQANILSGVYNLDHFMEDIHED----VIGRDLIERMISAEPESRPSAASILKHPFFWSPEKQLQFFQDVSDRIEKEPTESPIVARLENSGR---SVVRTNWRMHISAPLQADLRKFRTYKGNSVRDLLRAMRNKKHHYHELPPEVQSALGEVPDGFVAYFTSRFPRLLLHTHTALSICAPERPFHPYYHH-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JR46-1", "uniprot_id": "A8JR46_DROME", "id": "A8JR46-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MRFCVVVCCVLFLLASGLIASATAKSQQGD------------------------------------------------------------------SAEVVSSGEDEKTDCTDLARDEEALMVFSTLGGGLTAIDPVTSEIRWTIADDPPI---VAEHQENVQ--VPHFLPDPRDGSIYQLG--QMGSLKKLPYTIPQLVANAPCRSS-------------DGILYSGKKSDTWYMVDPKTGRREKVMG-------FGDATVDGKEGEQIGWATSR-AIYLGRTQYTVMMYDSLAKNKDAKPWNITFYDYNAVSAPPELAKEYEYIHLTTTTNGQIVTLDRKHGKFLWQRDLSSPVVAAFLLGPDGLLSVPFTTVSDEAYQ--AILEES---------------KTGNVNTVKLFQSLYVGEHQKGLYALPSLVDKNTPRISTAPPIKLLDGPTGDQNSNQE-TDPRTIYINDVLQEHAG--------------IMLGHYNMPNEGNGNLQLSPTTASSKVVQSLATIHNYN-------DGYGLLANNEKNAADIGVQTDPELVEIGIDQRTN---GNTINRTKTIILQNSNKVQAFINEWFMEHPSGKVHQILIVIVLG-------------------MIALFWYTCSTMRELQKQSENGSKTFAIAQNGSNGSTGSNGSNAN----AEDLVDLGNGQVRVGKISFSTNEVLGKGCEGTFVFKGTFEERFVAVKRLLPECFTFADREVALLRESDAHENVVRYFCTEQDRQFRYIAVELCAATLQDYTEGDRS----LELQNHIDVWQVLSQAASGLSHLHSLDIVHRDIKPQNVLISLPD--------AKGKVRVMISDFGLCKKLNFGKTSFSRRSGVT-GTDGWIAPEMMRSQ-------------------------------RTTTAVDIFSLGCVYYYVLSGGHHAFGDNLKRQANILSHEYNLAKLRPEDDSEDSRIILAEQLISDMIHKDPQSRPPARCIGNHPLFWDEPKMLSFLQDVSDRVEKLQFHAEPLKSLEKNGR---IVVLDDWNVHLDPMITDDLRKYRGYMGASVRDLLRALRNKKHHYHELTPAAQKMLGCIPHEFTNYWVDRFPQLISHAYHAFSICSNEPIFKPYYSAGYLFTRPWYFDADDALFPMLMLDPKPLPKIGSPKKTPSPASSQAQQLKQRKGLYNFRKPNDELPIPGVGLQRNLELDGQSLEPDGKRDVFANFKFRRYSKPGNNRNYNGGHKEAQDKEKYVIWTLPPSTQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32361-1", "uniprot_id": "IRE1_YEAST", "id": "P32361-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVASTKKLNFNYGVDKNINSPIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAANSISVPYLENRSLN--ELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEPSRLETYETLIIEPFGDGNIYYFN--AHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVEDEKVYTGSMRTIMYTINMLNGEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVIGKTIFELGIHSYDGASYN-VTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSLLASDLDFRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPFNPGDHESISSNKVYLDQTSNLSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKNAIMGVHQIYNNEYDHLYENY---EKTNSLDTTHKYPPLMIDSS---------VDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIHEQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQRFKILPPLYVLLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPFDMKSGK------------------QVVFEGAVNDGSLKSEKDNDDADEDDEKSLDLTTEKKKRKRGSRGGKKGRKSRIANIPNFEQSLKNLVVS-EKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRS--LIAEATDLISQMIDHDPLKRPTAMKVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIGVYMIVKENLSDDQILREFLYS----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: . ::. : : *.* *:. .. * *:: : : .. . :: **.:* :. .* *** :* :** :* : . * :* *. : :: .*. :: : : : :*:* : : ::. . :. : . : . . :.. : ::: * . * . : . : * *. : . : : .. : .*:... . . : . . : . : . . . .: : . :: . .. . . . : . . : : :: . .:** * .**.*::* *: * *****:* : :* *: ** *** * **:**:*:* :* ***:*** .**: .* . : :* * .*::*****.*:***:**:*:*:* .. .:: :********** *: ** . . . **.** ***:: . . * :**** ***:**: * * *.**.. *::**: .* : . . . :**. *: :* .**.* : .**:** * * *: .****:* . :: .. : :* :: : :*.::* * . .: *****:*** **: :*. . :* :*. * *:..*** *: .: . : : : ", "identical_positions": 164, "similar_positions": 225, "identity": "12.78%" }, { "cls_id": "homologset.agr.HGNC:34490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RB05-1", "uniprot_id": "M0RB05_RAT", "id": "M0RB05-1", "name": "", "aln": "MRCLPLFFSAMLAACVFSEEQTEGIT----IAYKVLEVYPRSRRVLITCDIREAPRPITYSLIASRGVLVAKKIVRDYTPASFNINITLKSSPDLLTYSCQAASNLGTYGPSSRLQMYSELWTKPVSQLQADFVLRDGDSGPTAELSCLASSGSPPITYRLVGNDGRVLAQQRPLHGKPANFSLPLSETSSGFQCVAENSISVDSSALILLPP-----AEARSELVTTLTGELPLAP-TCILAGSLISIVVITSGMLNLTRL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX63-1", "uniprot_id": "IL40_MOUSE", "id": "Q9CX63-1", "name": "Protein IL-40", "aln": "MALLQLLLFAMLAACGFSEEQTEGIT----IAYKVLEVYPQSRRVLITCDAPEASQPITYSLLASRGILVAKKVVHDSVPASFNINITIKSSPDLLTYSCQATSNSGTYGPSSRLQMYQELWAKPVSQLQADFVLRHGDSGPTVELSCLASSGSPPITYRLVGNGGRVLAQQRPLHGKPANFSLPLSQTTGWFQCEAENDVGVDSSARIPLPR-----AEARAKLVTTLAGELPLTP-TCILAGSLVSIAVIASRMLSSTGL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX52-1", "uniprot_id": "IL40_HUMAN", "id": "Q6UX52-1", "name": "Protein IL-40", "aln": "MGLPGLFCLAVLAASSFSKAREEEITPVVSIAYKVLEVFPKGRWVLITCCAPQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFCWASSTSGAHVDSARLQMHWELWSKPVSELRANFTLQDRGAGPRVEMICQASSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSDWFWCQAANNANVQHSALTVVPPGGDQKMEDWQGPLESPILALPLYRSTRRLSEEEFGGFRIGNGEVRGRKAAAM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: *:***. **: : * ** ********:*:.* ***** :.. ****** .::.: ****:*: *****:*:*:********* * *:*. *:: *:****: ***:****:*:*:*.*:. .:** .*: * ********* *:*:.*:* **** * :*****: *:*:. * * * *. .*: ** :* * : : *** * *: . .. * . : ", "identical_positions": 117, "similar_positions": 59, "identity": "44.15%" }, { "cls_id": "homologset.agr.HGNC:34491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UH99-1", "uniprot_id": "SHSA6_MOUSE", "id": "Q3UH99-1", "name": "Protein shisa-6", "aln": "MALRRLLLPPLLLSLLLSLASLHLPPGADAARGRSGNRTLNAG--AVGGRRAGGALARGGRELNSTARASGVPEAGSRRGQSAAAAAAAAAAASATVTYETCWGYYDVSGQYDKEFECNNSESGYLYCCGTCYYRFCCKKRHEKLDQRQCTNYQSPVWVQTPSTKVVSPGPENKYDPEKDKTNFTVYITCGVIAFVIVAGVFAKVSYDKAHRPPREMNIHRALADILRQQGPIPIAHCERETISAIDTSPKENTPVRSTSKNHYTPVRTAKQTP--------------------------------GDRQYNHPILSSATQTPTHEKPRMNNILTSATEPYDLSFSRSYQNLAHLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPRRGLPDEFGMPYDRILSDEQLLSTERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMTKMHSHPSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHHTCYTASKTEVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEE6-1", "uniprot_id": "A0A8I6AEE6_RAT", "id": "A0A8I6AEE6-1", "name": "", "aln": "MALRRLLLSPLLLSLLLSLASLHLPPGADAARGRSANRTLSAG--AVGGRRAGSALARGDRELNSTARGSGVSEAGSRRGQ----SAAAAAAASATVTYETCWGYYDVSGQYDKEFECNNSESGYLYCCGTCYYRFCCKKRHEKLDQRQCTNYQSPVWVQTPSTKVVSPGPENKYDPEKDKTNFTVYITCGVIAFVIVAGVFAKVSYDKAHRPPREMNIHRALADILRQQGPIPIAHCERETISAIDTSPKENTPVRSTSKNHYTPVRTAKQTPGHYGKDAYRSGGPDLHNFISSGFVTLGRGHTKGDRQYNHPILSSATQTPTHEKPRMNNILTSATEPYDLSFSRSYQNLAHLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPRRGLPDEFGMPYDRILSDEQLLSTERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMTKMHSHPSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHHTCYTASKTEVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZSJ9-1", "uniprot_id": "SHSA6_HUMAN", "id": "Q6ZSJ9-1", "name": "Protein shisa-6", "aln": "MALRR-----LLLLLLLSLESLDLLPSVHGARGRAANRTLSAGGAAVGGRRAGGALARGGRELNGTARAPGIPEAGSRRGQP---AAAVAAAASAAVTYETCWGYYDVSGQYDKEFECNNSESGYLYCCGTCYYRFCCKKRHEKLDQRQCTNYQSPVWVQTPSTKVVSPGPENKYDPEKDKTNFTVYITCGVIAFVIVAGVFAKVSYDKAHRPPREMNIHRALADILRQQGPIPIAHCERETISAIDTSPKENTPVRSSSKNHYTPVRTAKQTP---------------------------------------------------EKPRMNNILTSATEPYDLSFSRSFQNLAHLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPDRGLPDEFSMPYDRILSDEQLLSTERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMSKMHSHPSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHHTCYTASKTEVTV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** *** ***** **.* *....****:.****.** ********.*****.****.***..*:.******** :**.******:******************************************************************************************************************************************************************:*************** ***********************:************************************************************************************ *******.**********************************************************:**********************************************************", "identical_positions": 471, "similar_positions": 22, "identity": "84.26%" }, { "cls_id": "homologset.agr.HGNC:34492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW61-1", "uniprot_id": "F1LW61_RAT", "id": "F1LW61-1", "name": "", "aln": "MSRCYYDSPLRLEKAFVLDGVAVSSMAHAYSILRPKLWSAIPPYNPQLDHHAHRYFRSHVVPPVLRKTDQDHGGTGRDGWIVDYFHIFGQGQRYLNRRNWAGAGHSLQQVSGHDYYNANPKVITAGLNGRFGYRRNTPALRQRTSVFGEVTPFPIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAQ5-1", "uniprot_id": "SPMA1_MOUSE", "id": "Q9DAQ5-1", "name": "Sperm microtubule associated protein 1", "aln": "MA-CCYNSPRRLEKSFVLDGVAVSTMAQAYSIMRPKLWSAIPPYNPQLDHHSRRYFRSRVVPPILRKTDQDHGGTGRDGWIVDYFHIFGQGQRYLNRRNWAGAGHSLQQVSGHDYYNSNPKAITTGLNGRFGYRRNTPALRQHTSVFGEVTPFPIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MV24-1", "uniprot_id": "SPMA1_HUMAN", "id": "A8MV24-1", "name": "Sperm microtubule associated protein 1", "aln": "MA-YLSECRLRLEKGFILDGVAVSTAARAYGRSRPKLWSAIPPYNAQQDYHARSYFQSHVVPPLLRKTDQDHGGTGRDGWIVDYIHIFGQGQRYLNRRNWAGTGHSLQQVTGHDHYNADLKPID-GFNGRFGYRRNTPALRQSTSVFGEVTHFPLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. ****.*:*******: *:**. ************.* *:*:: **:*:****:********************:*****************:*******:***:**:: * * *:*************** ******** **:*", "identical_positions": 116, "similar_positions": 23, "identity": "74.36%" }, { "cls_id": "homologset.agr.HGNC:34493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNS8-1", "uniprot_id": "EPOP_MOUSE", "id": "Q7TNS8-1", "name": "Elongin BC and Polycomb repressive complex 2-associated protein", "aln": "METLCPPPRLAVPASPRGSPCSPTPLKPRRGTPEFSPLCLRALAFCALAKPRPSSLGLGPGELAPRTPVLLGPPASPCTGGWAADGLKHLGGQAGRPSDVSSPAREDADVAVCPGGGEEEEGGGGFPHFGAGSCAPPGRCPAPLRPQDSPTNPAWSPPRPARG----LDAASSPPLEPGSPPPSPPAGLSPEPA-PSEQP---VPASEAPGGGDPAPTAPEAPALSPSTADAAPDPPRDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPAAK--ARGAAKKRRRPAPPPPSVQPRRPVPTLPTSSTFSLLDCFPCPPALVVEENGDLGPASSLRLQGDAKPPPAHPLWKWQMGGPAVPEPPGLKSWWVNLEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RD31-1", "uniprot_id": "M0RD31_RAT", "id": "M0RD31-1", "name": "", "aln": "METLCPPPRLAVPASPRGSPCSPTPRKPRRGTPEFSPLCLRALAFCALAKPRPSSLGLGPGELAPRTPVLLGSRASPCTGGWAADGLKHLGAQAGRPSDVSSATREDADVAVCPDRGEEEEGGGGFPHFGSGSCTPPGRCPA--GPRESPTSPARSPPRPARGLESQLDAASSPPLGSSSRPPSPPAGLSPEPA-PTEQP---MRDSEAPEGGDPARVAPEAPALSPSTADATPDAPGDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPAAK--ARGAAKKRRRPAPPPRSVQPRRPAPTLPTSSTFHLLDCFPCPPALVVEENGDLGPASSLRLQGDAKPPPAHPLWKWQMGGPAVPEPPGLKSWWVNLEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NHQ4-1", "uniprot_id": "EPOP_HUMAN", "id": "A6NHQ4-1", "name": "Elongin BC and Polycomb repressive complex 2-associated protein", "aln": "METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPGLKFWGINMDES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.****************** ** *** *******************.**** ******.*:*** *. *. .****.****** . :***. .:.: ******.** ************** **:******* *::*.*. * :***** * ..*:*** ..* *********.*** * * : . * .*:*. .****** *****..:* .* *******:*****************************.** ********* ***** :.*****.*****:*** **:********** *:*** **********:*********:*************** * :*::* ", "identical_positions": 271, "similar_positions": 51, "identity": "71.5%" }, { "cls_id": "homologset.agr.HGNC:34494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8Q2-1", "uniprot_id": "A0ABK0M8Q2_RAT", "id": "A0ABK0M8Q2-1", "name": "", "aln": "---MASPLRSKSSVPRVESTRHKETSTVRMETSSHREETSSHRVETSSRQVLTSSRQVETSQRHREGPSLTPSAKRLPQFLEVSSQHVETSSQCMETSSRHVRASSSLRVETTVHRVESPARRDKQATRQSARMTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGJ3-1", "uniprot_id": "CQ100_MOUSE", "id": "Q8BGJ3-1", "name": "Uncharacterized protein C17orf100 homolog", "aln": "MGRMASPLRSKSSAPRVESTRHKETSTVRVETSSHREETSSHRVETSSRQVRTSSRQVETSQRHREGPSLTPSTKRLPQFLEVSSQHVETSSQCTETSSRHVRASSSLRVETTVHRVESPAR-------QSARMAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MU93-1", "uniprot_id": "CQ100_HUMAN", "id": "A8MU93-1", "name": "Uncharacterized protein C17orf100", "aln": "---MASARGAKQSSPRVGTTRYTETSTVRVETSSHRVETS--------------SRRVETSQRRSEGPSLSPSGKRLPRILEASSRHVESSSQRTETTSRHVRASS-LRVETSLHCAESPTPRAKPAARQNEKTAR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***. :*.* *** :**:.******:****** *** **:******: *****:** ****::**.**:***:*** **:******** *****::* .***: *. : :*", "identical_positions": 75, "similar_positions": 23, "identity": "55.15%" }, { "cls_id": "homologset.agr.HGNC:34495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DI92-1", "uniprot_id": "ZSWM9_MOUSE", "id": "Q6DI92-1", "name": "Uncharacterized protein ZSWIM9", "aln": "-------------------------------------------------------------------------------------------MELTEPLPSAAVQKEEQELLDRTFFSWAEFSRFFDKWCQQRLVVFSVKSSTRVARSPWANTPPLYRLIHVLKYSYVLLVCKDVRMPNKSTAWPPQPSCPAFITVKLSPLRDRLVVTECQLTHSHPACPREFAYHFRPGHLLANSCLPVRITNQISKQFVAPADVRRLLTHCKGPDHGVLDALQVLEGLFRTDPEAKVKLVFVEDQAMVETVFLLTSRTRALLRRFPRILLVDRLPGLQGTLDLMAVLCVDSAGRARQAACCVARPGTPSLLRFMLVSLLQSAPDVKGRVRCLTAGPEVAGQLRAVRQLLPCARVQICRAQGLETLFSKAQELGGASQEDPDLWPLLCRLADSKSYTAYSEALAELRSQAPTAFIRYFEHNWAPRHDMWVRFRAYEATRDLDACALVRSHRRRLLRRLSPSHSVAQCLRDLVAMQWADATGEAALRGC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHE3-1", "uniprot_id": "D3ZHE3_RAT", "id": "D3ZHE3-1", "name": "", "aln": "MGQSKERRGAVPHSMLGSGPEPILPVDEPVRLRGRKGDSRGEEKGWWKATLSGTGGRKAGYRAGHPGSKGRAGFGRGALWEVDAALGWGPKMELTEPSPSPAVQKEEQELLDRTFFSWAEFSRFFDKWCQQRLVVFSVKSSTRVARSPWANTPPLYRLIHVLKYSYVLLVCKDVRMSNKSTAWPPQPSCPAFITVKLSPLRDRLVVTECQLTHSHPACPREFAYHFRPGHLLANSCLPVRITNQISKQFVAPADVHRLLTHCKGPDHGVLDALQVLEGLFRTDPEAKVKLVFVEDQAMVESVFLLTSRTRALLRRFPRILLVDRLPGLQGALDLMAVLCVDSAGRARQAACCVARPGTPSLLRFMLVSLLQSAPDVKGRVRCLTAGPEVAGQLRAVRQLLPCARVQICRAQGLETLFSKAQELGGASQEDPDLWPLLCRLADSKSYTAYSEALAELRSQAPTAFIRYFEHNWAPRHDMWVRFRAYEATRDLDACALVRGHRRRLLRRLNPSHSVAQCLRDLVAMQWADATGEAASEGVNGDRVLLESEPRNRAQMEKEKVRGTEASNWGRPDRESEKGRGLHLRDSQGVWLENQKVRGPEGTGAQLEKEHLREPEVRDWKGTQTENRRVKVLGPTDQRGNQVESEKAKSLEERPRREVQLQGERARALKPQDWKEPRFEIEKGIDVRKWREVYVEKPLELVPENGDQRGPYLGADGQKGPDIAEERSGRFLVKRRRGLEDIVVVHLEDARATGIVNGNGGGPQPVGFKNGGQQIEFGDPGGRLPGIGNGVPCTTPVQTVLKGSPEWAVNRVKSLAAEDAVQGRDEEGPREPKRLCRPCRDEGVDCEPLAKFRAACGPELADLVAEELAFARQHGTRGFHWTGAGFALKDGISDFFLDGALTHCSCSIYAARHLPCRHLFAARLLTGAALFHVDLLRDCWGRSQEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86XI8-1", "uniprot_id": "ZSWM9_HUMAN", "id": "Q86XI8-1", "name": "Uncharacterized protein ZSWIM9", "aln": "-------------------------------------------------------------------------------------------MERPEPPPGTAAGQEEQELRERAFFSWAEFSRFFDAWCQQRLALFFVKSSMHLARCRWASAPPLYTLIDVLKYSYVRLVCKDVRAPSRPAVGPPQPGCPAFIIVKLSPLRDRLVVTECQLTHSHPACPLEFAYYFRPGHLLANACLPVRTTNKISKQFVAPADVRRLLSYCKGRDHGVLDALHVLEGLFRTDPEAKVKLVFVEDQAVVETVFFLTSRTRALLRRFPRMLLVDRLPGLQGALDLLAVLCVDGSGRARQAACCVARPGTPSLLRFALASLLQSAPDVKGRVRCLTAGPEVAAQLPAVRQLLPCARVQICRAQGLETLFSKAQELGGAGREDPGLWSRLCRLAGASSPAAYDEALAELHAHGPAAFVDYFERNWEPRRDMWVRFRAFEAARDLDACALVRGHRRRLLRRLSPSRGVAQCLRDLVAMQWADAAGEAVPEGPDGGGPWLEDEPGRGAQGENERVRGLETGDWGGAPKEGSIWRG-----------------------AQMEKEWARALETRDWGGAQFEGEKGRALQIRDWRGGRLENQKPRGLEGGVLRGSKLEKGHLRGPEIRDWRGPQLEGEK-----DWG-----------LEGYVWRGSQLEDQALRG---LEGYTWR-------------VAQLEDRRST---------------------------------------------TDLRG-TQFDYERGKGESTEDR------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .** *..*. :***** :*:************ ******.:* **** ::**. **.:**** **.******* ******* ..:.:. ****.***** ************************* ****:*********:***** **:***********:***::*** ********:***********************:**:**:**************:***********:***:******.:********************* *.***********************.** ********************************.:***.**. *****.:.* :**.******:::.*:**: ***:** **:********:**:**********.*********.**:.****************:***. .* ", "identical_positions": 358, "similar_positions": 65, "identity": "37.88%" }, { "cls_id": "homologset.agr.HGNC:34496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8Z4-1", "uniprot_id": "D4A8Z4_RAT", "id": "D4A8Z4-1", "name": "", "aln": "MENVRREATRPFVPSGTLELYFPDHLYRNDYLSMEGPRWAQAIKQAVRWKFTPMGQDAAGQMWYTGLTNSNPCDAWYMLPRALDMPYREAHTRWHGCFQSRQRDLPPAYTQHLRETAFWDPAIPPQYLNPGTRWGCLQWRDRQIRGKEFVVNRNQFGAELPRR-SDYVQDLSPPHRPRFTAQDFKQRGLDRPYPATGQ-PPPVFTPTL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H6Q4-1", "uniprot_id": "TKTI1_MOUSE", "id": "A6H6Q4-1", "name": "Tektin bundle-interacting protein 1", "aln": "MENVRREATRPSVPSGTLELYFPDHLYRNDYVSLEGPRWAPAIKQAVRWKFTPMGRDAAGQVWFTGLTNSEPGDAWYKLPRALDTPYREAHTRWHGCFQSRQRGLPPAYTQHLREMAFWDPAITAQYLNSGPRWGCMQWRDRQIRGKEFVVTRNQFGAKLPWR-SDYVPLLSLPQRPRFTAQDFRQRGLQRPCPAIGQ-PPPAFTPAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NCJ1-1", "uniprot_id": "TKTI1_HUMAN", "id": "A6NCJ1-1", "name": "Tektin bundle-interacting protein 1", "aln": "MQTLRQEAARPCIPSGTLEASFPAPLYSDDYLSLEGSRWPPAIRQATRWKYTPMGRDAAGQLWYTGLTNSDAWEAWYNLPRAPASPFREAYNRWHSCYQHRECSMPSAYTQHLRETAWHDPIVPAQYQAPSTRWGSALWKDRPIRGKEYVLNRNRYGVEPLWRASDYVPSLSAPQRPPGTTQNYREWVLEPYCPSTCQRSPPSLTPTPR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.:*:**:** :****** ** ** :**:*:**.**. **:**.***:****:*****:*:******:. :*** **** *:***:.***.*:* *: .:*.******** *: ** :..** ...***. *:** *****:*:.**::*.: * **** ** *:** *:*:::: *: *: * .** :**: ", "identical_positions": 111, "similar_positions": 56, "identity": "53.11%" }, { "cls_id": "homologset.agr.HGNC:34497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7N2-1", "uniprot_id": "ERIC4_RAT", "id": "P0C7N2-1", "name": "Glutamate-rich protein 4", "aln": "MELWAQLKQAGLESSGLGPLPQALRMPPPEGNPGQALMSSGAEFGGARELLLWIWEELGNLRRVDVQLLGQLCDLGLEMGTLREELVTILEEEEEDDDEEEQEEEGEGKNCVEENKGLQGKQGEKCSGNPYPAQRLPDFEMTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UNU4-1", "uniprot_id": "ERIC4_MOUSE", "id": "Q3UNU4-1", "name": "Glutamate-rich protein 4", "aln": "MEPWVQLKQAGLEPSGLGPLPKALRVPPPEGNPGQALMSSGAELGGARELILWIWEELGNLRRVDVQLLGQLCDLGLEMGTFREELVTILEEEEE---EEEQEE----KSCVEENKGPEEKQDEERSRSSYPAQRLPDFGMTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGS2-1", "uniprot_id": "ERIC4_HUMAN", "id": "A6NGS2-1", "name": "Glutamate-rich protein 4", "aln": "MELWRQLNQAGLVPPGLGPPPQALREVSPVEIPGQTLRTAGADTGGACDSLLWIREELGNLRRVDVQLLGQLCSLGLEMGALREELVTILEEEEE----SSKEE--------EEDQEPQRKQEEE-HLEACPAPHPPDFEMMI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * **:**** ..**** *:*** .* ***:* ::**: *** : :*** ******************.******::************* ..:** **:: : ** *: .. ** : *** * *", "identical_positions": 81, "similar_positions": 24, "identity": "56.64%" }, { "cls_id": "homologset.agr.HGNC:34498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R6K3-1", "uniprot_id": "M0R6K3_RAT", "id": "M0R6K3-1", "name": "", "aln": "MACTENGLGGHSRSSIMVPVDKNGSRETHHNVQLRCLSSMLKDDEDDAEVWPHPPVSLRPSFTMP-------------RTGARIPEN-PRALRHPFTLAPAIEEESLATAEINRSEGQESQSQKGHDSINMSQEVSASPMALMIGG-RVGSGVLERSGNNSKPYIPVPRANGFFPPRGSQSRGPPYIPTLRSGIMMEVTPGNARMAYKGNLAHVSFSLGSPRHPMDNWQQRPPLPLSTNITGLP-CSTAHCFLPPQAPAFNPFPVMPTAFASPLGFGPPLLPYFFHYNTGAIYPPPYLN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AFE9-1", "uniprot_id": "PRR32_MOUSE", "id": "A2AFE9-1", "name": "Proline-rich protein 32", "aln": "MACTENGLAGHSHSPIIVPVDKNRSKETCHNVQLRSLSSMLKDDEDDADVWTRPPVSLRPPFNVP-------------RTGARIPQN-PRAPRHPLTLTPAIEEESLATAEINSSEGLESQSQKGHDSINMSQEFSGSPMALMIGGPRVGSRVLERSGNNSKPYIPVPRSQGFFPPRGSQSRGPPYIPTLRSGIMMEVTPGNARMANRGNMAHVSFPLGSPRHPMDNWQQSPSLPLSPSITGLP-CSSAHCFLPPQAPAFNPFPVMPTAFASPLRFGPPLLPYVFHYNTGAMYPPPYLN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1ATL7-1", "uniprot_id": "PRR32_HUMAN", "id": "B1ATL7-1", "name": "Proline-rich protein 32", "aln": "MACIENVLGGHAPSPLVVSVDKNGNQELHHDMPLQCLSSKP---EDDAEPWGQPQVPLRPSVNVLTDLDSKQLEWPSERTGSCIPLHSLRAHRHPYGPPPAVAEESLATAEVNSSDALAGWRQEGQDAINVSWEVSGGPPALIVGGTKVNNGGTERGSNNARLHVALPQGKGFFPPRGPQVRGPSHIPTLRSGIVMEVPPGNTRIACRGKLAHVSFPLRGPCHPMHNWPR--PIPLSSSTPGLPSCSTVHCFIPPRPPIFNPFLTMPLPFAPPPIFGPPLPSYFAHFHSGGMPAPASPNREHS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** *.**: *.::*.**** .:* *:: *:.*** ****: * :* *.***...: ***: ** : ** *** .**: ********:* *:. . *:*:*:**:* *.*..* **::** :*.. **..**:: ::.:*:.:*******.* ***.:********:***.***:*:* :*::*****.* .* ***.** : .:***.. .*** **:.***:**:.* **** .** .**.* ***** .*. *:::*.: .*. * ", "identical_positions": 144, "similar_positions": 86, "identity": "47.52%" }, { "cls_id": "homologset.agr.HGNC:34499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4J1F8-1", "uniprot_id": "A0A0B4J1F8_MOUSE", "id": "A0A0B4J1F8-1", "name": "", "aln": "MAVTAALSAAAAAAALSGLAVRLSRWAATRSSYGAFCKGLTRTLLTFFDLAWRLRVNFPYFYMVASVMLNVRLQVRIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DMW4-1", "uniprot_id": "SIL2A_HUMAN", "id": "P0DMW4-1", "name": "Small integral membrane protein 10-like protein 2A", "aln": "MAASAALSAAAAAAALSGLAVRLSRSAAARGSYGAFCKGLTRTLLTFFDLAWRLRMNFPYFYIVASVMLNVRLQVRIE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:********************* **:*.************************:******:***************", "identical_positions": 71, "similar_positions": 6, "identity": "91.03%" }, { "cls_id": "homologset.agr.HGNC:34500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4J1F8-1", "uniprot_id": "A0A0B4J1F8_MOUSE", "id": "A0A0B4J1F8-1", "name": "", "aln": "MAVTAALSAAAAAAALSGLAVRLSRWAATRSSYGAFCKGLTRTLLTFFDLAWRLRVNFPYFYMVASVMLNVRLQVRIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DMW5-1", "uniprot_id": "SIL2B_HUMAN", "id": "P0DMW5-1", "name": "Small integral membrane protein 10-like protein 2B", "aln": "MAASAALSAAAAAAALSGLAVRLSRSAAARGSYGAFCKGLTRTLLTFFDLAWRLRMNFPYFYIVASVMLNVRLQVRIE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:********************* **:*.************************:******:***************", "identical_positions": 71, "similar_positions": 6, "identity": "91.03%" }, { "cls_id": "homologset.agr.HGNC:34511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8P9-1", "uniprot_id": "D3Z8P9_RAT", "id": "D3Z8P9-1", "name": "", "aln": "MTMAGRLGQKMNQDEVHQNQIMRELFLKEFRTQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLVHHAAQGPKKKYSETQTEAQEIGWDPHPLINPDRQDRRLNHFRVYHDITLYKAKLWSLGEDDHQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NC57-1", "uniprot_id": "CF144_MOUSE", "id": "Q5NC57-1", "name": "Cilia- and flagella-associated protein 144", "aln": "--MAGRVGQMKNQDEVHQNQILRELFLKELRAQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLIHHAAQGPKKKYSETQTEAQEIGWDPNPLINPDRQDHRLNHFRVYHDITLYKAKLWSLGEDDHQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZVS7-1", "uniprot_id": "F183B_HUMAN", "id": "Q6ZVS7-1", "name": "Protein CFAP144P1", "aln": "--MAGHPKERVVTDEVHQNQILRELYLKELRTQKLHTQYHVNPLRKVHRITRKPMSWHDNLEEPADARFLNLIHHAAQGPTKKYPEAQTENQEIGWDSEALVDPERRDHRMNHFRVYSDITLYKAKMWSLGEDDRHK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: : ********:***:***:*:***:************ *************** **:****:*******.***.*:*** ******...*::*:*:*:*:****** ********:*******::*", "identical_positions": 101, "similar_positions": 24, "identity": "73.72%" }, { "cls_id": "homologset.agr.HGNC:34517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTZ3-1", "uniprot_id": "D3ZTZ3_RAT", "id": "D3ZTZ3-1", "name": "", "aln": "MSEGESKDSSGSECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTIVCPICRYVTFLSKKSSRWPSMLDKSSQTLAVPVGLPSTPSPDRGGHTNPLVISHQVWRQ---------SPSQGTQLPLDLLPSLPRESQIFIISRHGMPLGEQDSVLPRRSLAEISEASPAPSATRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CEF8-1", "uniprot_id": "RN222_MOUSE", "id": "Q8CEF8-1", "name": "RING finger protein 222", "aln": "MSEGGSKDSSGSECPVCYEKFRDLDGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTIVCPICRYVTFLSKKSSRWPSMLDKSSQTLTVPVGLPSTPSPDRGGHTNPLVISHQVWRQ---------SSSQGSQVPLDLLPSLPRESQIFIISRHGMPLGEQDSVLPRRSLAEISEASPAPSATRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NCQ9-1", "uniprot_id": "RN222_HUMAN", "id": "A6NCQ9-1", "name": "RING finger protein 222", "aln": "MSEGESKDSSGSECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTLVCPICRYVTFLSKKSSRWPSMLDKSSQTLAVPVGLPSVPPLDSLGHTNPLAASSPAWRPPPGQARPPGSPGQSAQLPLDLLPSLPRESQIFVISRHGMPLGEQDSVLPRRSLAELSEASLAPRSARAFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *******************:*********************************:*****************************:*******.*. * ******. * .** *..*.:*:***************:**********************:**** ** ::*:*********************************:", "identical_positions": 183, "similar_positions": 18, "identity": "83.18%" }, { "cls_id": "homologset.agr.HGNC:34518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R1C3-1", "uniprot_id": "VOPP1_MOUSE", "id": "Q8R1C3-1", "name": "WW domain binding protein VOPP1", "aln": "MGRRLGRVAALLLGLLVECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPTFNVSYTRQPPNPAPGAQQMGPPYYTDPGGPGMNPVGNTMAMAFQVQPNSPHGGTTYPPPPSYCNTPPPPYEQVVKDK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEK8-1", "uniprot_id": "VOPP1_RAT", "id": "B5DEK8-1", "name": "WW domain binding protein VOPP1", "aln": "MARPLGRVAALLLGLLMECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPTFNVSYTRQPPNPAPGAQQMGPPYYTDPGGPGMNPVGNTMAMAFQVQPNSPHGGTTYPPPPSYCNTPPPPYEQVVKDK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96AW1-1", "uniprot_id": "VOPP1_HUMAN", "id": "Q96AW1-1", "name": "WW domain binding protein VOPP1", "aln": "MRRQPAKVAALLLGLLLECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPAFNVSYTRQPPNPGPGAQQPGPPYYTDPGGPGMNPVGNSMAMAFQVPPNSPQGSVACPPPPAYCNTPPPPYEQVVKAK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F4X8-1", "uniprot_id": "E7F4X8_DANRE", "id": "E7F4X8-1", "name": "WW domain binding protein VOPP1", "aln": "MRS--GGAAAVLLLTLLECVEAKKYCWYSEGGYPLFFICRSYEDCCGTRCCIRALSIQRLWYFWLLLMMGVFFCCSAGFFIRRRMYPSVLSDEPAFNVSFTRQPVS-TPVSQQ---PVMQGFGEPCVG-MGASLTPVYSGQSPAAAMMSSYPPPPSYCNHPPPAYDQLFSSAEKKSRSESPQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NG32-1", "uniprot_id": "A0A8M1NG32_DANRE", "id": "A0A8M1NG32-1", "name": "WW domain binding protein VOPP1", "aln": "MRQICGLLITLLF---AETVAEKKYCWYFEGDYPVYFICKAYEDCCGTECCVRALAVQRIWYFWLLLIIAILCCCSTGYFIRRRAHPYPPSDRPEFTVAFSRNPII-TPGLRQ-----------TGFHSYGDSETAVISTVFPAVSALSYYSQGP-HPHHPPPSYEQVMQDSQKK-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ::*: * . **:*** ** ** ::**::******:.**:***::**:****:**::.:: **.:*:***** :* :.* *.*:::*:* * :* . . * : : . . : . * : : ***.*:*:.. ", "identical_positions": 56, "similar_positions": 49, "identity": "30.77%" }, { "cls_id": "homologset.agr.HGNC:34519", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LTB5-1", "uniprot_id": "A0ABK0LTB5_RAT", "id": "A0ABK0LTB5-1", "name": "KRAB domain-containing protein", "aln": "MELGDSGKVPVTFDDITVYLLQEEWMLLGQPQKDFSTSDKLTASLGETHVN-----------------------------------YMEE-------REKGQYLPPQKKTCHAPYFSTESSTMEKDSTGGNRKPPKPRSIQKSWFTKFPWLIMNEEQTALFCAICREYPSVRDKRSRLIEGYRGPFKVETLKYHAKSKAHIFCVHALAAKDPVWAAHLQNLRESPADLLASPEHLLTADNPTFYLPGPLGNFDGIDELLSSPRAEPEDTSGSGAIPALSLDCESDLRQKEIGSDILSPSNGSTLFKDSTDFCSQEPPDQEWPEGFRES-GEPPATFEDLAVYFTREEWSLLGKQQKELYSDVMRMNYELLASLAEPPAATPDLITKLEQRAAPWIEDPNGLKSGKSRSLGREKMEATREANSQTQASALEFVSQPASVETCSVHRSPSMCEEEVDGPRNVKSTYRPRSIQRSWFGQFPWLVMDSKETKLFCSVCKERPTLHDKSSRLVQGYTGPFKVETLKYHEVSKAHKLCVNTVEIRDDSPQPTLTPEISGALMANMEHFFNAAYSIAYHSRPLNDFEKVLQQLQNTGTTLLGKYRNRTACTQFIKHISETLKKEILRDIRNSPCVSLLLDSCVDSSSQACVGIFMRYLKQTEVKESYITLAPLSSETVDGYFETIIAALDELDIPFRKPGWVVGLGTDGSAMLSCKGGLTEKFREIIPQLLPVHSVAHRLHVAVVDACSDIDLVRKCDRHIRTVFKFYQSSNKRLSELQGVAAPLEQEIIRLKDLNAVRWVASRRCTLNAFVMNWPALVRHLQSVVEAGGQVGQRAKGIMKLMKSFHFIKFCHFILDFLSIYKPLSEVCQKDLVLVTELNSTLGRAYVALESLRQQAGPKEEAFNAGFQDGQLHGIFLNRVEMAEQRFQADRERTVLTGAEFLQQRFGADRPAQLRSMAVFDTTAWPRGAELACFGNHDILSLARYFALSLPVGYREEALLKEWLSLKAATQNLPFSTLCKSALTQPGQFPLLSRLVAVVVSVPISTACCARGFKAMSRIRTDERTKLSNEVLNTLMMTAVNGVAVTEYDPQPAIQHWYLTSSGRRFSHLYACAQVPTRSHANTGFRKEGMAAALSKEDSVTQKTSGTPSGEP----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60290-1", "uniprot_id": "ZN862_HUMAN", "id": "O60290-1", "name": "Zinc finger protein 862", "aln": "MEPRESGKAPVTFDDITVYLLQEEWVLLSQQQKELCGSNKLVAPLGPTVANPELFRKFGRGPEPWLGSVQGQRSLLEHHPGKKQMGYMGEMEVQGPTRESGQSLPPQKK-AYLSHLSTGSGHIEGDWAGRNRKLLKPRSIQKSWFVQFPWLIMNEEQTALFCSACREYPSIRDKRSRLIEGYTGPFKVETLKYHAKSKAHMFCVNALAARDPIWAARFRSIRDPPGDVLASPEPLFTADCPIFYPPGPLGGFDSMAELLPSSRAELEDPGGDGAIPAMYLDCISDLRQKEITDGIHSSSDINILYNDAVESCIQDPSAEGLSEEVPVVFEELPVVFEDVAVYFTREEWGMLDKRQKELYRDVMRMNYELLASLG-PAAAKPDLISKLERRAAPWIKDPNGPKWGKGRPPGNKKMVAVREADTQASAADSALLPG-SPVEARASCCSSSICEEG-DGPRRIKRTYRPRSIQRSWFGQFPWLVIDPKETKLFCSACIERPNLHDKSSRLVRGYTGPFKVETLKYHEVSKAHRLCVNTVEIKEDTPHTALVPEISSDLMANMEHFFNAAYSIAYHSRPLNDFEKILQLLQSTGTVILGKYRNRTACTQFIKYISETLKREILEDVRNSPCVSVLLDSSTDASEQACVGIYIRYFKQMEVKESYITLAPLYSETADGYFETIVSALDELDIPFRKPGWVVGLGTDGSAMLSCRGGLVEKFQEVIPQLLPVHCVAHRLHLAVVDACGSIDLVKKCDRHIRTVFKFYQSSNKRLNELQEGAAPLEQEIIRLKDLNAVRWVASRRRTLHALLVSWPALARHLQRVAEAGGQIGHRAKGMLKLMRGFHFVKFCHFLLDFLSIYRPLSEVCQKEIVLITEVNATLGRAYVALESLRHQAGPKEEEFNASFKDGRLHGICLDKLEVAEQRFQADRERTVLTGIEYLQQRFDADRPPQLKNMEVFDTMAWPSGIELASFGNDDILNLARYFECSLPTGYSEEALLEEWLGLKTIAQHLPFSMLCKNALAQHCRFPLLSKLMAVVVCVPISTSCCERGFKAMNRIRTDERTKLSNEVLNMLMMTAVNGVAVTEYDPQPAIQHWYLTSSGRRFSHVYTCAQVPARSPASARLRKEEMG-ALYVEEPRTQKPPILPSREAAEVLKDCIMEPPERLLYPHTSQEAPGMS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :***.****************:**.* **::. *:**.*.** * .* ** * **.** ****** .: .::** *. :* * :* *** **********.:***************: ******:*********** *****************:***:****:**:***:::.:*:.*.*:***** *:*** * ** *****.**.: ***.*.*** **..*.*****: *** ******** ..* *.*: . *::*:.: * *:*. : .* . * *..***:*********.:*.*:***** *************. *.**.****:***:******:**** * **.*. *.:** *.***::*:.*: ::. :.**: : *.*:*** ****.:* *******************:*.********.* ***.*********:********************:********::*:*:.:*.****. ***************************:** **.***.:***************:******:***.*:*******:****..*:*.******::**:** ************ ***.*******::****************************:***.***:*:********.******:******..****:********************.*** ************************ **:*:::.****.**** *.*****:*:****::***:.***:*****:*******:********::**:**:*:*************:******* ***.*:**:**** *:::*:**************** *:*****.****.**:.* **** *** * ***.***.***.***** ***.** *****:***.**: :*:**** ***.**:* :*****:*:****.*****:** ******.**************** **********************************:*:*****:** *.: :*** *. ** *:. ***.. ** *. ", "identical_positions": 806, "similar_positions": 202, "identity": "68.65%" }, { "cls_id": "homologset.agr.HGNC:34520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IRH8-1", "uniprot_id": "Q8IRH8_DROME", "id": "Q8IRH8-1", "name": "", "aln": "-------MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQN-----NHISSSSNISRSGGGNGRDKRGAQLD----------PSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKP----------KPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQ-YTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEEND-RLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSP------------------------------CSFETYFVCEVQPN-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6ZS10-1", "uniprot_id": "CL17A_HUMAN", "id": "Q6ZS10-1", "name": "C-type lectin domain family 17, member A", "aln": "----MHNLYSITGYPDPPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENS-TPPYKDLPPKPGSSAPPRPPRAAKETEKPPLPCKPRNMTGLDLAAVTCPPP-----QLAVNLEPSPLQPSLAATPVPWLNQRSGGP------GCCQKRWMVYLCLLVVTSLFLGCLGLTVTLIKYQELMEELRMLSFQQMTWRTNMTGMAGLAGLKHDIARVRADTNQSLVELWGLLD-CRRITCPEGWLPFEGKCYYFSPSTKS-WDEARMFCQENYSHLVIINSFAEHN-FVAKAHGSP----RVYWLGLNDRAQEGDWRWLD-GSPVTLSFWEPEEPNNIHDEDCATMN---------KGGTWNDLS------------------------------CYKTTYWICERKCSC----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7Z0K3-1", "uniprot_id": "B7Z0K3_DROME", "id": "B7Z0K3-1", "name": "C-type lectin domain-containing protein", "aln": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGG--LNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . :. : :. .: .. . . : . : . .: * :. : : : . : : : * . . .: : . . : : ..: . . . : . : . : : **:. : * * *: **. :.. *:: : . . :*:. : * . *:. . . . : *: * : . :* * *::** : . ", "identical_positions": 20, "similar_positions": 83, "identity": "4.38%" }, { "cls_id": "homologset.agr.HGNC:34521", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A5WUG5-1", "uniprot_id": "A5WUG5_DANRE", "id": "A5WUG5-1", "name": "", "aln": "------------------------------------MAQTLYFPLLLIALCSISECVQRQYHFINENKTWTEAQRYCREKYTDLATVDNMNDTIQLNKS--VNDVR------LWIGLQR-----KWQWSSGD--PELFLNWESGQPDGKD-----ECAFMRHGKWHDGKCSDTWFVICYNM----------------------------SRGLVFVNQTMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDSIPS--RSDVWIGLFRD-WQWSDQSNYSFSYWNTNEPNNYGNNENCTVLKENTNGHWADISCD-CQFPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQY--------------------------------------------------------------------------------------------------------------------KVMNVVKLASTGAVWLGLRHS-CALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRS---------------------------------------------GAVQSGGDQTWISRPETDRLNFICRNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A5WUJ5-1", "uniprot_id": "A5WUJ5_DANRE", "id": "A5WUJ5-1", "name": "", "aln": "------------------------------------MGQFLDSLLLLVALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDNMNDMIQLMKSVKVNDRG------VWIGLQR-----KWQWSSGD--PALFLHWGNEQPDGAD-----ECAFMRNGQWEDGKCNDSWIFVCYNM----------------------------SRGLVFVNQAMTWRAAQSYCRQNHTDLVSVRNQNESQQLEKFINDSHKF--ASEVWIGLFRDSWQWSDRSNYSFSYWNNQEPNDYGGKENCTVVQPKTEGRWNDIVCN-NLFPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQY--------------------------------------------------------------------------------------------------------------------KVMNVVKLASTEAVWLGLRHS-CALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRS---------------------------------------------GAVQSGGSQTWISRPETHKLNFICRNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RF17-1", "uniprot_id": "A0A8M1RF17_DANRE", "id": "A0A8M1RF17-1", "name": "", "aln": "------------------------------------MAQSLYFPLLLIALCSISECVQRQYHFINEKKTWTEAQRYCREKYTDLATVDNMNDTTELMKS--VYDVR------LWIGLQR-----KWQWSSGG--PALFLNWGYNQPDGSD-----ECAFMKNGVWHDGKCSDTWIFVCYNM----------------------------SRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLENFINDRNSS--GSAVWIGLFRDSWQWSDQSTYSFSYWNNQEPNNVGGNENCTVLMENTQGHWADISCD-RQFPFVCH-----EDKLIVIQQNLSWSEALRYCRQHHVDLVSVQSVEMQY--------------------------------------------------------------------------------------------------------------------EVMNVVKLASTEAVWLGLRFS-HILGIWFWVSGETVYYRNWAPGNGTSEEDCEPTVRS---------------------------------------------GAVQSGGNQTWISRPETDKLNFICSRYE---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q208-1", "uniprot_id": "A0A8M9Q208_DANRE", "id": "A0A8M9Q208-1", "name": "", "aln": "------------------------------------MAQTLYFPLLLIALCSISECVQRQYHFIHEKKTWTEAQRYCREKYTDLATVDNMNDTIQLMKS--VNDER------IWIGLQR-----KWQWSSGD--PALFLNWAYRQPDGKD-----ECAFMINGEWHDGACSNTLFFICYNM----------------------------SRGLVFVDQMMNWRDAQSYCRQNHTDLVTVRNQNESQQLEKFINDSNSS--GSAVWIGLFRD-WQWSDQSNYSFRYWDTNQPDNQGGTENCAVITQNVQGRWNDISCD-HQFPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQR--------------------------------------------------------------------------------------------------------------------RVMNVVKLASTEAVWLGLRFS-HILGIWYWVSGETVFYQNWAPGNGTSEEDCEPTVRS---------------------------------------------GAVQSGGSQTWISRPETDRLNFICSRYG---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G2Y2-1", "uniprot_id": "A0AC58G2Y2_DANRE", "id": "A0AC58G2Y2-1", "name": "", "aln": "---------------------MDKHSEAFSLKQISEMAQKLQFFLLLIALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDSMNDTTELMKI--VNNVR------LWIGLER-----KWQWSSGD--PVLFLNWGDKQPDGKD-----ECAFMRNGEWHDWPCNKDCFFVCYNR----------------------------SRGLVFVNERKNWTDAQSHCRLHYTDLVSVRNQNENQQLEKFINDSPKPEPGSDVWIGLFRDSWQWSDQSNYSFSNWKLGEPNNVGDHENCTAVEKDAQGQWIDISCD-HQLPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQY--------------------------------------------------------------------------------------------------------------------EVMSDVKKASTEAVWLGLRFS-HILGIWFWVSGETVCYQNWAPGNGTSEENCEATVRS---------------------------------------------GAVQSGGDQTWISRPETHKLNFICSKY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TYY6-1", "uniprot_id": "A0AB32TYY6_DANRE", "id": "A0AB32TYY6-1", "name": "", "aln": "------------------------------------MSQAQYI-LLLIALCSISECVQRQYHFINEKKNLTEAQRYCRENYTDLATVDNMNNMIQLNKS--VNDER------VWIGLQRTS-VYKWHWSSGD--PALFLNWASGQPVGSD-----NCTYMTNGQWIVGPCSAISPFICYNM----------------------------SRGLVFVNQTVNWRAAQSYCRQNHTDLVIVRNQNESQQLEQFINDRQLS--GGAIWIGLFRDPWQWSDQSNSSFRYWKTTEPDNYGGIENCTVIEENAQGRWADYPCY-WKMPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQR--------------------------------------------------------------------------------------------------------------------RVMNVVKLASTEAVWLGLHHY-CSMNMWLWLTGDMVCYQNWAPGNGSTPENCKLENRK---------------------------------------------GAVQSGGDQTWISLPESHRLNFICTN-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YZA0-1", "uniprot_id": "A0A8M6YZA0_DANRE", "id": "A0A8M6YZA0-1", "name": "", "aln": "------------------------------------MAQALFF-LQLVALCSVSECVQHQYYFINQVKNWTEAQRYCRENYTDLATADNMNDTIELIKP--VNKARA---QNIWIGLRKTS-VYTWHWSSGD--TVLFLNWASGQPASSN-----NCTVMRNGHWFDWSCSATCFFICYNT----------------------------NSGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSS--GSAVWIGLFRDTWQWSDHSNSSFRYWNTAEPNNYGGDENCSVIETNAQRGWADNPCH-YQFPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQR--------------------------------------------------------------------------------------------------------------------RVMNVVKLASTEAVWLGLHNY-CSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRK---------------------------------------------GAVQSGGDQTWISLPESHTLNFICTNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N7C8-1", "uniprot_id": "A0A8M1N7C8_DANRE", "id": "A0A8M1N7C8-1", "name": "", "aln": "------------------------------------MAQTLYSSLLLIALCSISECVQHQYYYINVNKTWTEAQRYCREKYTDLATIDNMNELNNMNKL--VKSENNGATEYVWTGLQRMS-VYKWHWSSGD--PALLLNWASGQPAGSD-----DCAVMRNGQWFDEPCSKTWIFICYNT----------------------------NTGLVFVDQLMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSS--GSAVWIGLFRDTWQWSDQSNSSFRYWNTAEPNNAGGIQNCIGMNQNAQGRWHDISCT-GSFPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQR--------------------------------------------------------------------------------------------------------------------RVMNVVKLASTEAVWLGLHNY-CSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRK---------------------------------------------GAVQSGGDQTWISLPESHRLNFICTNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8A7-1", "uniprot_id": "Q1L8A7_DANRE", "id": "Q1L8A7-1", "name": "", "aln": "------------------------------------MAQTLYLSLLLIALCSISECVQRQYHFINKNKTWTEAQRYCREKYTDLATVDNMNDMIQMNKS--VKVNDG----YAWIGLQRTS-VYKWHWSSGD--SVLFLNWASGQPAGGD-----NCTVMRNGKWFVEPCSDAWTFICYNM----------------------------SRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSS--GSAVWIGLFRDTWQWSDQSNSSFRYWDTIEPNNAGGHENCAVIYLYNLKQWNDILCD-RQYAFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQR--------------------------------------------------------------------------------------------------------------------RVMNVVKLASTEAVWLGLHNF-CSMNMWLWLSGDMVCYQNWAPGNGSTPENCKLENRK---------------------------------------------GAVQSGGDQTWISLPESHRLNFICTNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P3G7-1", "uniprot_id": "A0A8M1P3G7_DANRE", "id": "A0A8M1P3G7-1", "name": "", "aln": "------------------------------------MAQSLYFPLHLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDLIQLKKS--ANNEGV---QNIWIGLQRTG-VYKWYWSSGD--PALFLNWASGEPAGSE-----ECAVMRNGQWIVWLCSNVSFFICNNT----------------------------STGLVFVNQSMTWREAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSS--GSAVWIGLFRDTWQWLDQSNSSFRYWYPGEPNNYGGHEDCAVIGKNTQRGWADVPCDSRQIPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQR--------------------------------------------------------------------------------------------------------------------RVMNVVKLASTEAVWLGLHHY-CSMNMWLWVSGDMVCYQNWAPGNGSTPENCKLENRK---------------------------------------------GAVQSGGNQTWISLPESHRLNFICTNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F6PDD5-1", "uniprot_id": "F6PDD5_DANRE", "id": "F6PDD5-1", "name": "", "aln": "------------------------------------MAQTLYIPLLLIALCSISECVQRQYHFINEGRNQTEAQKYCREKYTDLATVDNMSDMNQLIKS--VNNGGV---ENIWIGLQRTS-VYKWHWSSGD--PVLFLNWTSGEPAGSN-----ECTVMHNGQWINEACSNTRFFICYNM----------------------------STGLVFVDQMMNWRDAQSYCRQNHTDLVSVRNQNENQQLEKFINDRNSS--GAEVWIGLFRDSWQWSDQSNSSFRYWNTGEPNNV--EESCAVIGKNPQRGWADVLCDGRKIPFVCH-----EDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQY--------------------------------------------------------------------------------------------------------------------KVMNVVKLASTEAVWLGLRHS-CALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRS---------------------------------------------GAVQSGGNQTWISRPETDRLNFICRNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NE49-1", "uniprot_id": "A0A8M1NE49_DANRE", "id": "A0A8M1NE49-1", "name": "", "aln": "------------------------------------MAQSLFFPLLLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDMIQLNKS--VNNVNN---QNIYIGLQKTN-VSKWHWSSGD--LVLFLNWASGEPNNSY-----NCGTIKNGQWFAESCNNTCFFICYNM----------------------------SRGLVFVNQNMNWTVAQSYCRQNHIDLVTVRNQNESQQLEKFINDRNSS--GSAVWIGLFRDTWQWSDQSNSSFRYWAA----NFKDSSYSAAIQPNISGQWADYSSNYNQFPFVCH-----EDKLIVIQQTKSWSEALRYCRQNHVDLVSVQSVEMQY--------------------------------------------------------------------------------------------------------------------EVMNVVKLASTEAVWLGLRHS-CALGIWFWVSGQTVCYQYWAPGNGTSEEDCEPTVRS---------------------------------------------GAVQSGGDQTWISRPEIDKLNFICRNY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H6E4-1", "uniprot_id": "A0AC58H6E4_DANRE", "id": "A0AC58H6E4-1", "name": "", "aln": "MKSKKEKSSTVSQWVAQSPHSKKVTGSSPSRRGSGVMHESLFMLLLLSGLLRMNSELYRDYYFINIRMSWPEAQSYCRAKYTDLATAESTDDVNRLLNSVGAQYNGS-----VWIGLKRGT-QKRWGWSYGDNTIAQYTAWSNGEPSSTN-----ECGFLAYGNWRTYNCSDLIYFACYN-----------------------------GTGYTMLTMWMNWTDAQSYCRKHYIDLPTIHNSTELAQINSAVS------YNAWLWIGLFKDSWEWSDKWGWFFRYWAVGQPSPSAGSSDCVGMSTTNFGKWASYSCG-LQQPFICYGGTKFPYIYQYVNKSMTWPDAQSYCRARFTDLATVDTMDDVN--------------------------------------------------------------------------------------------------------------------RLVNIVDPGFSGSVWIGLQNGGQNRWIWSLGNGVLSTYSFWNPGEPSGDGDCGSSTYGNWSDESCSTVLPFLCFDDHTGFAIINTAMTWRDAQSYCRHYHTDLATIDSVDQQHMISTQSTLWIGLFLDSWGWSDQDILSFRYWAPDQPPLSSVSGDCAGLSTADFGQWAQYSCNLQQNFICYGDDSLINKQIVHIKLSCKDKCTPNDPTLQTAFLNKINEKLRSLGLERKSKISWKQSEDEEVFHEETYPPTNY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6ZU45-1", "uniprot_id": "CL20A_HUMAN", "id": "Q6ZU45-1", "name": "Putative C-type lectin domain family 20 member A", "aln": "-------------------------------------MLPRALLLSFCAAALQLVSSKRDLVLVKEALSWYDAQQHCRLHYTDLADLQPS----GLWKLYSLMTSTP-----AWIGLFFDASTSGLRWSSGS--TFTALEWGQKLPEFGVGFCATLYTWLKLPSIGAASCTAQKPFLCYCDPDVGHLISTKPSLS-LTTSPKPAVVQISGQTFMRFDQVMTWSSALLYCRSHHTDLADLQMVTDETGKEALRSIMSETEAWIGLYLNANSGSLSWSSDLGASIPSWLQ-VPMMVRGLCTALGIYMTYSPKVYSVNCS-SLLPFFCFYDSSTGHRASAELPPLFHTSP------TEMTEETTPRPGR-----------------------------------------------------------------------------------------------------------------------AVASVGSGTDRRDTAAATEAQHLSS----ESKEKTSAQKSGHPFGILKADFTISTLM----------------------------------------------DPEEMKDQFLRQIQEVLKLTLGHEQFRLKWVSFEVNKK----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LXV6-1", "uniprot_id": "A0ABK0LXV6_RAT", "id": "A0ABK0LXV6-1", "name": "", "aln": "--------------------------------------------------------------------MWY-----CQEHYTDLADLQSMNSLVSVMVVYSYTSSVQ-----AWIGLFYDVRISGLSWSSGS--VFTMPTWS-KLPVFQDGVCATLYSWYGVPALGAASCTGQKPFICYFDPAVGHRISLVSPLKDLTTLPEEAEVKIGGQTFIRIKQTMTWLSALTYCRHHYTDLADLQRVTDKD-KDSLKPVINGDDAWIGLYFSVKINHLTWSSDQGSSIPEWLQEMPMFGQGLCAGIRTFANHPPQIYALLCP-DLKPFICFNDPSIGHRQSAEMPSLIDTSSPRVTQHSKVPTRTTSRPNTGTSTDSTDASQVLDSASWIPRQVSHEPTAVSSGTCGFRTCDTTTPASTTVGLTALQSQGMVSIRPVATSAYPGETKERTTEASVSGSTAEVQGNWTSVPAAWNPDTSTGTAGSLPGTTTAMTTVEGGIYKGDTTSATEAQHLCSPKYPESKKKAAASESEHSFGILKADFAIPALR----------------------------------------------DPEEMKDQLLSEIQEVLKLILGHEEFTLKWIGSEVNKK----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :***** : : : ** ** *. * * *. . * . . .* * :** :: ** :: .: : :::. . * . : * . .*.*. ... :. : * . . . : :. .* . . : : ", "identical_positions": 27, "similar_positions": 47, "identity": "3.66%" }, { "cls_id": "homologset.agr.HGNC:34522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UXS0-1", "uniprot_id": "CL19A_HUMAN", "id": "Q6UXS0-1", "name": "C-type lectin domain family 19 member A", "aln": "-------------------MQRWTLWA----------------------------AAFLTLHSAQAFPQTDISISPALPELP----LPSLCPLFWMEFKGHCYRFFPLNKTWAEADLYCSEFSVGRKSAKLASIHSWEENVFVYDLVNSCVPGIPADVWTGLHDHRQEGQFEWTDGSSYDYSYWDGSQPDDGVHADPEEEDCVQIWYRPTSALRSWNDNTCSRKFPFVCKIPSLTIH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYE6-1", "uniprot_id": "A0AC58IYE6_DANRE", "id": "A0AC58IYE6-1", "name": "", "aln": "MSQLIFLKWISEMLNDALEMSTFSLLAWLKAYDPENECLILWSLKKDNQCTLLKKALLFSGFSAWALPSTNIKITQALPMQLSDSNQPVTCPLFWTEFEGYCYRFFPLNRTWAEADLYCAEFSNGHKSAKLTSVHSWEENVFVYDLVNSRMPGIPTDIWIGLHDRRQEGTMEWTDGSPFEYSYWDGNQPDDGIHRIPEEEDCVEIWYRQNSALRSWNDNNCDKAFPFVCKIPTLEN-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ::* * * ::: .** *:*.*:*.*: *** * ***** **:*:********:*********:*** *:*****:*:*************** :****:*:* ****:**** :******.::******.*****:* *******:**** .*********.*.: ********:* ", "identical_positions": 127, "similar_positions": 35, "identity": "53.59%" }, { "cls_id": "homologset.agr.HGNC:34524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B7SUM8-1", "uniprot_id": "FBP12_RAT", "id": "B7SUM8-1", "name": "Fatty acid-binding protein 12", "aln": "MVDQLQGTWKSVSCENFENYMKELGAGRAIRKLGCLARPVVTISTDGDRITIKTKSIFKNKEISFKLGEEFEEITPGGRKSKSTVVLDNDSLVQVQDWDGKEATIRRRLVDGKMV------VESAVNNVTCTRTYQRV---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAK4-1", "uniprot_id": "FBP12_MOUSE", "id": "Q9DAK4-1", "name": "Fatty acid-binding protein 12", "aln": "MVDQLQGTWKSVSCDNFENYMKELGVGRASRKLGCLAKPTVTISTDGDLITIKTKSIFKNKEISFKLGEEFEETTPSGRKSKSTVILDNDSLVQVQDWDGKEATICRRLVDGKMV------VESAVNNVTCTRTYQRV---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFH5-1", "uniprot_id": "FBP12_HUMAN", "id": "A6NFH5-1", "name": "Fatty acid-binding protein 12", "aln": "MIDQLQGTWKSISCENSEDYMKELGIGRASRKLGRLAKPTVTISTDGDVITIKTKSIFKNNEISFKLGEEFEEITPGGHKTKSKVTLDKESLIQVQDWDGKETTITRKLVDGKMV------VESTVNSVICTRTYEKVSSNSVSNS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INK3-1", "uniprot_id": "Q8INK3_DROME", "id": "Q8INK3-1", "name": "Fatty acid-binding protein, muscle", "aln": "-MSFVGKKYKLDKSENFDEYMKELGVGLVTRKMGNSLSPTVEVTLEGDTYTLTTTSTFKTSAISFKLGVEFDEETLDGRNVKSIITLDGNKLTQEQKGD-KPTTIVREFTDNELITLIPHLTPSQHGSLRLRVPCQPVPPTSVDDGARSGGCGQRPGGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .:* ..:* ::****** * . **:* *.* :: :** *:.*.* **.. ****** **:* * .*:: ** : ** :.* * *. * * :** *.:.*.::: . * ..: . : * ", "identical_positions": 47, "similar_positions": 43, "identity": "29.56%" }, { "cls_id": "homologset.agr.HGNC:34527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKF4-1", "uniprot_id": "A0ABK0LKF4_RAT", "id": "A0ABK0LKF4-1", "name": "", "aln": "MMMLRLLEFLFALLIPVFPSLPWSTDILESKGPGTVLQTFLFNCSSYMPT--LELLSVKPPTSFFNKPSLQGQKGLYRGKVTLSSSARLDALAVNYYELQLRYTCGNFVVDGSFFVHVLRDPGRIHCTGAFASPAGEFIYVPETVTPGALLYTLLLPGLGGQRAQMNITSAQDPPVFPGPFSIDEHGLLRAPSQGLRGQAQKTFQLQILVSLGKSQRCKGMLTVKVLPAPPSHVSFLKKAQSITIAEDLVPGSEVVQVQARGLNLLYEIISPRPSPLYSIGQADGVVRTTAPLDLVRVQGAVVTKLQVKAFERLRPWASAVSDLTVIVRAVNQRPPRCHPALLVTQIPETALEGTVLDTLTCVDPDSAGAPLDYQLRFHSPPDSASLRLRGRTLEVNATLDCDAPGACFQHLASILVSDGGQPQMTAEVPVLVMVTPVNEFSPSCMPHTFRVREDAGPYTLLGSIVGTDVDHPRNSLEYHISGGLSTFAVDRLSGELHLLGPLDYEQQRLYRIVILLIDHSQDWDLNSHRSGSCTITIEVEDVNDHAPECEPPFQELTIYTALGRSMEVTKVSCWIPQEPQRLTLSYSIMGGNSQSRFRLQGTILVYNDTVLGPPWPEPPSTHELLIHVADMGPSTPHLSTTATIIVHLVPWKASTVATSTHQSTVSSTMTPLIVTDVEAFWKPEPWFVVVLTATGAVLLLALGWLLGRILRRLAQSLQAPSKPARAQLLNSIQGSRGSIERQMEAPSMEMSK--------QHFDGRAQDVCNFSEAPVVPDDDPDLVLSQLFGEGKGDGGTGRDYLFSTLTGARRWL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "H3BJZ2-1", "uniprot_id": "H3BJZ2_MOUSE", "id": "H3BJZ2-1", "name": "", "aln": "MALLRLLEFLFALLIPVLYSLPWTMYISENNGPGTVLRPFSFNCSSYMPT--LELLSVRPPTSFFNKPSMHGDKGVYLVMVSLSSSARLDALAVNQYELQLQYRCGNFVVDGSIFVHVQRDPGRIRCTGAFASPAGEFIYVPETITPGALVYTLLLP--GVQRAQINITSAQNP--SPGPFSIDEQGLLRAPSQGLRGQAQKTFQLQISVSFEKNQSCRGMLTVKVLPAPSSQVSFLQKAQSITISEDLVPGSEVVRVQATGFNLLYEIISPRPSLFYSIGQADGVVRTTAPLDLARVQGAMVTKLQVRAFERPRPWASAVFDLTVSVRAVNQWPPRCHPALLVTQIPETSLVGTVLDALTCVDPDSAGRPLDYQLRFHSPPDSASLRLRDRILEVNATLDCDTPGACFQHSASILVVDGGQPQMTTEIPVLVMVTPVNEFSPACVPRTFRVQEDTGPHTLLGSIVGTDMDYPRNSLEYYISGGPSTFAVDRLSGELHLLGPLDYEQQRLYKITILLIDHSQDWDLNSHRSGSCTITIEVEDVNDHAPECEPPFQELTIYTPMGHSMEVTKVSCWIPQEPQRLTLSYSIVGGNSQSRFRLQGAILVYNDTVLGPPWPEQPCTYELLIHVADVGPSIPHLSTTTTIIVHLVPWKASTVATSTHQSTVSSTMTPLIVTELEAFWKPEPWFVVVLTATGAVLLLALGWLLSRILRGLAPSLQAPSKPAKAQLLNSIQGNEGPIERQMEAPRIEMSQVPRTAMSLQHFDGRAQDVC-----------------------------MGRDYLFNTLTGARRWL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6H8M9-1", "uniprot_id": "CDHR4_HUMAN", "id": "A6H8M9-1", "name": "Cadherin-related family member 4", "aln": "MVLLRLLVFLFAPVVSDLCSLPCFINVSESQGPGTVLQFLSFNCSSYTPTPTLELLNVQPPTTFFNPPSLARWQGTYVGKLTLSSSAQLDALMVNHYKVQLKFTCGNHVMEGSLSVDVQRDLSHIQCAGQFASPAGEMIQVPETVTPGARLYTLLLPGLELHGAQMSIISAQDLPHFPGPFSINEQGWLQAPSQGLLGQAQKVFQLQISVSFGQRQSCQGMVIVKVLPVPSSQVSFLEQAQNITIPENLAPGSEVVQVQARGVDLRYEILSPVPSPLFSIGRADGVVRTTTPLELARTSGTAVSRLQVKAFEQGQLWASAKLNLTMNVQLVNLWPPRCLPALLVSQIPETAPVGTVLNTLTCEDPDSVGATLDYKLWFRSSSNPASLCLYDRVLEVNATLDCDTPGACFQHAASILVLDGGQPQMTTEVPVLVMVTPINEFSPACAPRTFRVQEDAAPHTLLGSVVGTDMDYPHDNIEYYTSGGPTTFAVDRLSGEVHLLGPLDYEQQRLYRLTVLVIDHGQDQNPNHHLSGSCTITIEVEDVNDHAPECEPPFQELTIYAPLGRSVEVTKMSCQIPQEPQRLIYSYSIVGGNSQNRFILQGAILVHSDLVLGPFWPEQPRTYELLICVADAGPSTPHLSTTATIIVHLVPRRASTVATSTHRTTVPSTMTPMLVTDTEAFWQPQPWFVVVLTATGALLLLALGWLLGRLLQGLAQLLQAPSKPAQALLLNSIQGTEGSIEGFLEAPKMEMSQAPSSVMS-LHFDGRAQDSR-----------------------------TGRDYLFNTHTGARRWL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**** **** ::. : *** : *.:******: : ****** ** ****.*:***:*** **: :* * ::*****:**** ** *::**:: ***.*::**: *.* ** .:*:*:* *******:* ****:**** :****** : **:.* ***: ******:*:* *:****** *****.***** **: : * *:**: *****.*.*:****::**.***.*:*.******:*** *.:* ***:** ** ::***:********:**:*.*..*: *::***:***: : **** :**: *: ** **** *****:*****: ****::*** ****.* .***:* *:*..:.*** * .* **********:******* ***** ********:*:********:*****:* *:****:**:.*:*****:****:*:*::.:**: *** :**********:**************::.:*:***.** : * * ******************************:.:*:*:****:** ******** ****:*****.** ***:***:.* **** *** * *:**** *** *** ******:******** :*********::**.*****::**: ****:*:************:*********.*:*: ** ********:* *******..*.** :*** :***: ******** ******.* *******", "identical_positions": 526, "similar_positions": 150, "identity": "64.3%" }, { "cls_id": "homologset.agr.HGNC:34528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQN3-1", "uniprot_id": "TOM6_MOUSE", "id": "Q9CQN3-1", "name": "Mitochondrial import receptor subunit TOM6 homolog", "aln": "MASSGVTVSAAGSASEASEVPDNVGDWLRGVFRFATDRNDFRRNLILNLGLFAAGVWLARNLSDIDLMAPQPGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96B49-1", "uniprot_id": "TOM6_HUMAN", "id": "Q96B49-1", "name": "Mitochondrial import receptor subunit TOM6 homolog", "aln": "MASSTVPVSAAGSANETPEIPDNVGDWLRGVYRFATDRNDFRRNLILNLGLFAAGVWLARNLSDIDLMAPQPGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WBS5-1", "uniprot_id": "X1WBS5_DANRE", "id": "X1WBS5-1", "name": "", "aln": "---------MSGKKSEG--KSGGVTGWISSACRFAADRNDFRRNLLVNLGLFAAGVWVARNLSDFDLMSPQPVT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. .* ...* .*: .. ***:*********::**********:******:***:*** .", "identical_positions": 38, "similar_positions": 17, "identity": "51.35%" }, { "cls_id": "homologset.agr.HGNC:34530", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAM2-1", "uniprot_id": "EFCB9_MOUSE", "id": "Q9DAM2-1", "name": "EF-hand calcium-binding domain-containing protein 9", "aln": "MKLTPGCFLWYLYMDKIYCLLSLRNVKALMVYFHLLDVHHRNTLNDVLFFHFLQHVTNLNKSQIGMIFDLLDWTAVGEIGFDQFYVLICILLAHQDHLEDHFMYRHSRPVFELLDLDGEMNIGAANFQNYRFLFNIKKQELRDLFHDFDITGDRLLNYKEFKLYTIFCTDKSIDRKKRRKDREAAREREKEKGKDKEKYLHLKKIYSSMLSHRSIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZFC8-1", "uniprot_id": "D3ZFC8_RAT", "id": "D3ZFC8-1", "name": "", "aln": "MKLTQGSFLWYLYMDKIYCLLSLRNVKALMEYFHLLDVHHRNTLNDVLFFHFLRHVTNLRSSQIKMIFDLLDWTAVGEIGFDQFYVLVCILLAHQNHLEDHFMYRHSRPVFDLLDLDGELNIGVTNFQNYRFLFNIKKQELRDLFHDFDITGDRLLNYKEFKLYTIFCTDKSIDRKKRRKEREEVREKEKDKGKDKEKYLHLKKLYSSVLSHRSLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MZ26-1", "uniprot_id": "EFCB9_HUMAN", "id": "A8MZ26-1", "name": "EF-hand calcium-binding domain-containing protein 9", "aln": "MRLKQGSFLWYLYLDKIYCLLSVRNVKALAEYFHILDVHGKNTLNDVLFYHFLHHVTDLKKAQINIVFDMLDWNAVGEIDFEKFYMLVCMLLAHQNHLEGQFMYRHSRPVFDLLDLKGDLRIGAKNFEMYRFLFNIQKQELKDLFRDFDITGDNRLNYQEFKLYTIIYTDKLQKRQK---------TEEKEKGERK------RSLYSKCHIK----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*. *.******:********:****** ***:**** :********:***:***:*..:** ::**:***.*****.*::**:*:*:*****:***.:**********:****.*::.**. **: *******:****:***:*******. ***:*******: *** .*:* .**:**: * :.:**. : ", "identical_positions": 132, "similar_positions": 49, "identity": "61.11%" }, { "cls_id": "homologset.agr.HGNC:34531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA55-1", "uniprot_id": "D4AA55_RAT", "id": "D4AA55-1", "name": "", "aln": "MDPVLDRELQAKLYLEKHRIMELLSQLTSFLLFARPKKPRDYLISLLERLKVAKLTGVAFPYFMDNSNIVSMFEMMDNAGKGTISFVQYKEALKNLGLYTEDEVLG-DDGHAITLDKFRDEVN-----------KRMKEMWSVF-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D581-1", "uniprot_id": "EFC10_MOUSE", "id": "Q9D581-1", "name": "EF-hand calcium-binding domain-containing protein 10", "aln": "MEPVADRELQAKLYLERHRIMELLNQLTSFLLFARPKKPREYLISLLERLRVAKATHVAFPYFMDNSNTVSMFEMMDMAGRGCISFVQYKEALKNLGLCTADEVLN-DDGHIITLDTFRDEMN-----------KRMEKMWSMF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFE3-1", "uniprot_id": "EFC10_HUMAN", "id": "A6NFE3-1", "name": "EF-hand calcium-binding domain-containing protein 10", "aln": "METSS-RELQAAEYLEKHQIKEVVSYLTSALLFFRPEKPKEYLISLLERLRIAKVTGVAFPFFMDNSNIVAMFEMMDSSGRGTISFVQYKEALKTLGLCTEDEDLQ-DDGHKITLDKFKEEVN-----------KRMKEI---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RI62-1", "uniprot_id": "A0A8M1RI62_DANRE", "id": "A0A8M1RI62-1", "name": "", "aln": "--MSSPREREAAEYIKKHEIVDLMDNLTSMLFFYRPDRPRKFLIDQLEKLKISKDHQGNTPCLLNVSNLDALFGILDPSNQGCITYGQYKEVLKTIGIKNFSAFPDGASENKISQETFIREVISLILCLGQTACKMCKNIQAVEELNNY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :* *:::*.* :::. *** *:* **.:*:.:**. **:*:::* * ::: ** ::* ::* :.:* *:: ****.**.:*: . . . : *: :.* *: * ::: ", "identical_positions": 38, "similar_positions": 47, "identity": "25.5%" }, { "cls_id": "homologset.agr.HGNC:34532", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8MWE9-1", "uniprot_id": "EFCB8_HUMAN", "id": "A8MWE9-1", "name": "EF-hand calcium-binding domain-containing protein 8", "aln": "-----------------------------------------------------------MSSEDLAEIPQLQKLSIPHGFQNKEAASSPTPSITLSQVPDLQPGSQLFTEIHLAKIEKMFEEDINS-TGALGMDAFIKAMKKVLSSVSDEMLKELFLKVDSDCEGFVTWQKYVDYMMREFQGKEDMRKSQYRLHFYLPMTVVPL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C9R9-1", "uniprot_id": "EFCB8_MOUSE", "id": "Q8C9R9-1", "name": "EF-hand calcium-binding domain-containing protein 8", "aln": "MPSSLHAPLSGEVSAFSLSCPYFRCQDSTGEDLGRFPSPLPFLMCLLLFFPFRARWPRLMSSEKPGESPKPQKMAQPGGSQKKETSRSVPVTDPTSHNSEINQRDQQFSDMHLADLQKVFEKEADE-NGALKKEGFIRIMKGVLSSMSEEMLELLFLKVDSDCNGFVTWQKYVDYMMREFQGKEEMRKSQYRLRFHLPMTVIPL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AS75-1", "uniprot_id": "A0A8I6AS75_RAT", "id": "A0A8I6AS75-1", "name": "WD repeat-containing protein on Y chromosome", "aln": "-----------------------------------------------------------MSSEESGESPQSQKMAQPGGVQ-EETSKTYPVTSSVSQSSEIHQSTQQFTEMHLADLQKVFEKEADE-NGALKKEGFIKVMKWVLSNMSEEMLEVLFLKVDSDCNGFVTWQKYVDYMMREFQGKEEMRKSQYRLRFHLPMTVIPLHHGSEVVKVAFLTQGFKKIGCFLTVTKDGILQFWSETFSMMDSFRLTQTKQFGHQQMWVVDVAYLHNMNLIAVASTELKIEFFDISGYKCIRAFTFIDLDSCAMAMHYWTDYHKAVFCFGDTKGNVVIFISDNVVGGLFNPQILPRTSKWDHWIPVSLRRLLNKKSPLYRSFRMKGLHPNWCQQIKYIPQLNVVVSCSAVEKSSLVLIILPPKDPERPKLSS-LSLRKGILCFDYCPDRNFLATGGYDPHIRLWNPLVSKRPVWLMKGHQTSVTHLLVSSKNASILISISRDKNVRVWDLQDYVCLQSFCGKLFPLGNCPITSAYFHRSSTLICSTYNIGILRGYLESQGPLKTGRITTHNTPVCTILYSKIFKQVVSGCLQGIVSVWDISTGKKRMELP-------VSGIQESELTAMSLDESERCLLTGLRDGTVQMWNYNTGECLLTFPNPDKVEISGIVHMNKVYYMTGWSKRITNFTFQKATQTFSCYHWQSFHTEDILSMDKYQNQFLGTSSYNGDIVFWNVSTMKPILSFNASKSPLPLQPKKVRETETCAPKSPAHLDFEVQKWAHKPWKSTASTVKRRLMSAPPVMKHWKDTEQERNVAQEKHFRSNKPGLSKMLFDKSTHKPPFYKDAQMRKGEFWQKMLLQSSVSVEKIIFLQTRPRLPHTAALLSSCIDGFIYAWSIHGNGGLLGKFSVDPKDTGCVVGAMATDENNWILLTGDSKGNIKIWDIKDYCCFIGQQPFHSSGSSISGDTENKFRLLIPKELQIYSQHHLLQKEKEVVEGQTISLVPPPLLITWNSHMDSVTDILYVDSFRLVVSASEDRDVKAWKFFGEMIGTFGLGLWNRLQEAAVTDKLEQAESLEKKPDFTGAALKHSFLELDKELAEALVYQRREQAALMALLHGKAEKETEAWYRLQQMSLLSPWSKDSSMEDIEESWNRWAKDKQASKIVGAAYKPKLRVRNPKLLTSRAQFNWMRQQISPQIYQCLSFTDLKPVQQPDFLMHKILDQEGRHIRWVASDNRSELEFFRGQIFTDITSPATHSSLSTLSVGPSASNWSTSLKPHSSGSFVRPSSASPVHSSSSTSPQQTSGLLRRGQRPQGQLLSPSCSIRIPGEPPSCPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B4F7L9-1", "uniprot_id": "WDY_DROME", "id": "B4F7L9-1", "name": "WD repeat-containing protein on Y chromosome", "aln": "-----------------------------------------------------------------------MSVIFNASVNTKSAVEYQTISSTQSHSAEE-QSERLHKWISKDQLEKLYSSFLNTPERHVGIDELRIILEELDITFNDSMYTRLFLKINQNRDFKVDWNEFVSYLIFGFQEED---PSSQKESLILPISGPPMVR----------KSEHRSAICCLALLKAKSDQVPIDEVTETINFSFGGEDSPEASGMWVTASHEG----------------MMRFWTSHMEPIRTASSESICMSYAFFNNGKVHSKLILGDYAGNVRVLSYSPHLRGPFQAKPG------AALIEVVWSDILRGKIPQFFPKEYINLHNEMVSCVYFSLHMNALFASAEYRNTKKYRGRCPGMIMVTYDERSNFRIPLGVSTFFVAESHNIVVTGGPDTFVRIWDVYIPTEPSAILTGHNGGIVLVFVQPEEN-KVYSVDYQKIIKVWDLHEHTLLQTYGDLVRLIHHSETDLTYYYHSHLRELVVAGRKLISIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVSCGLDSYIIVWDPWTGRRKIIMKSCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNMSIMPDQEVTAVIWVVDRILAMGWDRQVTEFNDVVGREYGDPKKWPKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYSVMDPTRFIELKLTAEEEKFIRQSKRLASRLTHSGNHSLQTGRAG-----------------------------------------------------RSTVLNRPEDNRDYGTDIPISVQAVLFLQTRPQTLKHGSVFISLDTGFIQVYSHHQRGGYIVEFLAVHKTGDCVLT-MCTDRKNRYLYTGTAFGYIKVWYIVNFCVPESEKTHVCMPKLR-------------LEFIFLRKELFMTRAKRAVR----NQAEPLLVSSYKGHLKAINSIAFINLPKIIFTGSHDYSCRLWTQGGRYLGTLGTVLP-----------------------------------------------------------------------WSRLTPFERAGDDNHLYRMPPDIKKVASSTTLKVISGIQAETSIKISNGKTVEDREEE-----TAQTEDVTELRKLLDKPVKEPIVGKHFELPGRSILDQHIELDTTQSYIAVFTQLKVHSTEMLERLPTPAVVSRVQTENYMDHYIPVEGKVDVSGSAINIKQPSRRRSDKASDTRNVNTLGARDHVPLDFSSSHASQS------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : :.: . : . *: .: : .. : .::*::.. : : : : :: : ...:.* ****::.: : * *:::*.*:: ** :: *. : : **:: *: ", "identical_positions": 17, "similar_positions": 55, "identity": "1.28%" }, { "cls_id": "homologset.agr.HGNC:34548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ87-1", "uniprot_id": "MADL2_RAT", "id": "B2RZ87-1", "name": "Myeloid-associated differentiation marker-like protein 2", "aln": "MGSTMEPPGGAYLHLGAVTSPVGTARMLQLAFGCTTFSLVAHRGGFGGVQGTFCMAAWGFCFAFSVLVVACEFTRLHSCLRLSWGNFTAAFAMLATLLCATAAVIYPLYFTRLECPPEPAGCMVRNFRLAASVFAGLLFLAYAAEVALTRARPGQVASYMATVSGLLKIVQAFVACIIFGALVHESRYGRYVATQWCVAVYSLCFMATVAVVVLSVMGHTGGLGCPFDRLVVVYTFLAVLLYLSAAVIWPVFCFDPKYGEPGRPSDCPRGSCPWDSQLVVAIFTYVNLLLYIVDLAYSQRIRFVPTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08AU7-1", "uniprot_id": "MADL2_MOUSE", "id": "Q08AU7-1", "name": "Myeloid-associated differentiation marker-like protein 2", "aln": "MGSTMEPPGGAYLHLGAVTSPVGTARMLQLAFGCTTFSLVAHRGGFGGVQGTFCMAAWGFCFAFSVLVVACEFTKLHSCLRLSWGNFTAAFAMLATLLCATAAVIYPLYFTRLECPPEPAGCMVRNFRLAASVFAGLLFLAYAAEVALTRARPGQVASYMATVSGLLKIVQAFVACIIFGALVHESRYGRYVATQWCVAVYSLCFMATVAVVVLSVMGHTAGLGCPFDRLVIVYTFLAVLLYLSAAVIWPVFCFDPKYGEPGRPADCLRGSCPWDSQLVVAIFTYVNLLLYIVDLAYSQRIRFVPTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NDP7-1", "uniprot_id": "MADL2_HUMAN", "id": "A6NDP7-1", "name": "Myeloid-associated differentiation marker-like protein 2", "aln": "MGSTMEPPGGAYLHLGAVTSPVGTARVLQLAFGCTTFSLVAHRGGFAGVQGTFCMAAWGFCFAVSALVVACEFTRLHGCLRLSWGNFTAAFAMLATLLCATAAVLYPLYFARRECSPEPAGCAARDFRLAASVFAGLLFLAYAVEVALTRARPGQVSSYMATVSGLLKIVQAFVACIIFGALVHDSRYGRYVATQWCVAVYSLCFLATVAVVALSVMGHTGGLGCPFDRLVVVYTFLAVLLYLSAAVIWPVFCFDPKYGEPKRPPNCARGSCPWDSQLVVAIFTYVNLLLYVVDLAYSQRIRFVPSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************:*******************.****************.*.********:**.**************************:*****:* **.****** .*:*****************.************:***************************:********************:******.*******.**********:***************************** **.:* ***********************:*************:*", "identical_positions": 281, "similar_positions": 22, "identity": "91.53%" }, { "cls_id": "homologset.agr.HGNC:34549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSU9-1", "uniprot_id": "A0A8I5ZSU9_RAT", "id": "A0A8I5ZSU9-1", "name": "", "aln": "---MEGGPEQFHQGK------ALEEAGNGQALAEIQELALKWFMETQAPSILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRAAGYILSYRGSDRCRHFVINQLRNRRYLVSGDTLSHSTLDELLRHYQEVQLEPFGETLAAACPRLEENDLYDAINTGLQQTNLGLEIP-AMELPSMLPDKVTSPCLPAKPQVSFLHTKKALDASSRTGSNEESTEVPTRVPPIPQKSPSLLDDSSAGPSGIVYSELKKMNRAQLGPGTEVWGRHRPAPAGNLASSPGREPSRKLSDEDQNKPNSPEPAPSGEKPDQGSTMPYTSLGFPLPPNSEAQGSRATTWRQGFLKLSHEAQSSSEASSADTYQLAETSGLRQEGRDKPDQRGSTYEQIPSCWHSAAKLPCPGVSPTYSQLSGPMDYGYEKIPGTPQLPEPGNTYEQIPAAKNKDTGRVHKPDKFRRLFFTDKKHKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BI17-1", "uniprot_id": "SH2D7_MOUSE", "id": "Q8BI17-1", "name": "SH2 domain-containing protein 7", "aln": "---MEGGPEQLHLGK------ALEEAGGGRALAEIQELALKWFMETQAPSILQNGVLPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRAVGYILSYRGSDRCRHFVINQLRNRRYLVSGDTLSHSTLDELLRHYQEVQLEPFGETLAAACPRLEENDLYDAINTGLQHTNLSLKIP-ATEFPSMLPDKATSPRLPAKPQVSFLH-KKALDMSSRSVSDEVSAEVPTRVPPIPRRSPSLLDESPAGPSDVIYTDLRKINRAQLGLGTEVWGTLRPASAGSLACSPGREPSGKLSDEDQNKPNSLGPAPSGMKPDQGSTMPYTSLGFSLPPSSETLGSQATTWRQGFLKLSHEAQSSSEASSTDTYHLVETPGLQQEARDRPDQRGSPYEQIPTCWHGTAKLSYPGVSPTYSQQSGPMDYGYEKISGTSKLPEPGNTYEQIPAAKNKDTGRVHKPDKFRRLFFTDKKHKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKC9-1", "uniprot_id": "SH2D7_HUMAN", "id": "A6NKC9-1", "name": "SH2 domain-containing protein 7", "aln": "---MEDSLKQLSLGR------DPEGAGDSQALAELQELALKWFMETQAPFILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRATGYILSYRGSDRCRHFVINQLRNRRYIISGDTQSHSTLAELVHHYQEAQLEPFKEMLTAACPRPEDNDLYDAITRGLHQTIVDPENPPATAFLTVVPDKAASPRSSPKPQVSFLHAQKSLDVSPRNLSQEESMEAPIRVSPLPEKSSSLLEESFGGPSDIIYADLRRMNQARLGLGTEGSGRHGPVPAGSQAYSPGREAQRRLSDGEQNRPDGLGPVLSGVSPDQGPTESPTSWG-----CSDAMGSLGATWRQEFPKLSQEAQPCSQGSSADIYEFIGTEGLLQEARDTPDQEGSTYEQIPACWGGPARAPHPGASPTYS----PWVHGYKRISGTPELSEPGNTYEQIPATKSKETGRTHKPDKLRRLFFTYRKHKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRU3-1", "uniprot_id": "A0A8M9PRU3_DANRE", "id": "A0A8M9PRU3-1", "name": "", "aln": "MLTMEQIEAAMYQKMKKSDRLNEEKMEGFTMEGGQKEQILQWFVETQAMFILSDGNFPRWFQGFISRQEAEDQLRDRDVGCFLIRLSEKAIGYILSYKGQDRCRHFVINQTKTGLFVVSGDSTTHNSLAELIDHFKITPIQPFGEYLTSYSTEMDTVEEDDGNE--LYDVVQNSPIVTSGVSVKALTSLWEQATNCPHNMAPVLPSKSNRKLTTSTSIDRNSLSQAMKIPSLPKKNAPLRNSLSAG-----------LPGTNPSHEQHSITESRTSEHYSSQLWPTHHENGQSLTSNSYNPTPSMPQQPPPAPLMTASCSYAVLD-------------PKKMHSGAGRMANMEETELQPNPLYQASTVAYAGLKNQPEVEYDNRANPNDNVLLAENLYQDVPEERDYNTYEH--VPESNTYEDIP--VKVSNMYASLDEIQTQTPNTLG--KKNHKWWKLRLENKK---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : * . . :* *:**:**** **.:* :* **:***:*:::*: ***: :*.******::* ******:*.********** :. :::***: :*.:* **: *:: . ::** * *:: ... : : *. * .. . : . :.. .. .: ...* :. . :. . :. * . . ::..:*.:...* :. .* : :. . . . . * :. . : :. .* * . * .: . : . . :. :::: :. : .. ** :: . *:.... ::: . . **. * *: *. ::.: : ::* : . : * :* .* :* : :* ", "identical_positions": 87, "similar_positions": 146, "identity": "18.55%" }, { "cls_id": "homologset.agr.HGNC:34550", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W4R3-1", "uniprot_id": "Q9W4R3_DROME", "id": "Q9W4R3-1", "name": "", "aln": "-------------------------------MPVSAKRLLRNFQFTS----------------CDRNGKMLIHLLLIVS-----------------------------------------------------------LLEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGYRVG-----------WLKADTKA-----IQAIHENVITHNPRVTVSHL-----DQNTWNLHIKAVSEEDRGGYMCQLNT-DPMK-SQIGFLDVVIPPDFIS--EDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKD-NVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASNGVPPS-VSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPKSINYWIK----------------DTG----EMIVTSGKYHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIP-GPNRNKNPLNGGGKGGGAGGSLDADANDILKQKQQVKVTYQPEDEELQYGSVEDFEAEGGEGGGLTPLSPHVYYTSGNKPATHKPGNSGGNQHLHQQHHHHHHHNNNNNNQQHSGGPGGGPTGGDAG---------SLGGEMGGITRKPPPYYGGNTEVRGPIDNNEMSSGSGDSRLCRGHHLPILLLPFARLILVRSWHCRHTFLMG-----------------------------------LSQACLPGLLLSLL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z153-1", "uniprot_id": "B7Z153_DROME", "id": "B7Z153-1", "name": "", "aln": "MMNLLVVKESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLGTGTGTGSGCGPAIRWQLLLLLLLGNCIDLT--------------------------------------------------VSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKA-----ILAIHEHVITNNDRLSVQHN-----DYNTWTLNIRGVKMEDAGKYMCQVNT-DPMK-MQTATLEVVIPPDIIN--EETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARN-GSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPT-VSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQR----------------ENG----EMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEME-RPG--KKILR------------DDDLNEVSK-NEVVQKDTRSED-------------------GSRNLNGRLYKDR----APDQHPASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAGPTTLSCR---------TKGGRQ---KKAKETSWNGRRARDGREDGH-----AAEWRQCWER---------------SALSWRRSAPPE-----------------------------------LDYYSLIQL----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAR6-1", "uniprot_id": "Q9VAR6_DROME", "id": "Q9VAR6-1", "name": "", "aln": "------------------------------MEKLLQSTLFVILIMAT---------------KCGSGSTQNQHHE----------------------------------------------------------------SSSQLDPDPEFIGFINNVTYPAGREAILACSVRNLGKNKVG-----------WLRASDQT-----VLALQGRVVTHNARISVMHQ-----DMHTWKLKISKLRESDRGCYMCQINT-SPMK-KQVGCIDVQVPPDIIN--EESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPA-VSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITER-RDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKLHPG--ASASN------------DDHLNYIGGLEEAAR-------------------------------------------------NAGRSNRTTWQPLLAMLMLLWMRLSLRTGGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7PLL7-1", "uniprot_id": "Q7PLL7_DROME", "id": "Q7PLL7-1", "name": "", "aln": "--------------------------------MLTKKTARIKMYNGT----------------LACSIAFILIKAITITKCHAVA--------------------------------------------------HIHGKGESEEIDPQFLAKLSNTTVPIGRDISFTCVVDNLGHYRVA-----------WIKSDSKA-----ILGIHTHMVSLNPRLSVTHN-----GHNTWKLHISRVQINDSGSYMCQVNT-DPMK-SLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGKEIILRT-DGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPS-VSKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYR----------------SEGN---IKLHNGNKYNISEEVINIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTGKS--RRKHPASHKKGLNEVLRFQETHFAN-------------------QIQQENEDHNEGFDLLKFTNSENSNIVLESGHINSMINKEDVNIYHPKQYGQEKTNKPSGTIP---------STRTPWILTNAGSQRPALTSYATVALITSFWLFFWRVFHSLDWDAIRVSSVVHHVVVFKRRSYFEAPNYALR-----------------------------------ITVLQMLQELRTLVIEQ--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN9-1", "uniprot_id": "Q9VMN9_DROME", "id": "Q9VMN9-1", "name": "", "aln": "---------------------------MQSNFCQCRKQ--------------------------TCALSVILLLILMSQQCYPQR---------------------------------------------VEVPAEVIVD-------PKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVA-----------WLRVDTQT-----ILTIQNHVITKNQRIGIANS-----EHKTWTMRIKDIKESDKGWYMCQINT-DPMK-SQMGYLDVVVPPDILDY--PTSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELAT-----GEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPS-VSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRER---------------GEIVP-----PGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIPPN--------------------AVNYVENFEARHKGKKRTK------------SSES-------HHPARAQEHSGEDMENP-----GKRKADLS--------LGAES--------IDSIYGNSA--------------AGSRRR--------------------------QDLGGVLLLLLPVAVAVAMSLATAGVMRETQMTLPPQT------------------------------------LTHV---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN6-1", "uniprot_id": "Q9VMN6_DROME", "id": "Q9VMN6-1", "name": "", "aln": "------------------MKIKIFPLTADAATIAARRQRRRAAGKLQRKREMPEISSRLIVATATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIGESEEHDHIAHHLAEMQNKDELLEDIREDTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIA-----------WLRVDTQT-----ILTIQNHVITKNHRMSITHA-----EKRAWILRIRDVKESDKGWYMCQINT-DPMK-SQVGYLDVVVPPDILDY--PTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPN-----GAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPT-VSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKN----------------DTIIV-----PGERFVPETFESG-YKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPT----------VSINTVPVVLVKYNKEQRYG------------SSQNSNTNPYNFNPGNSQQNTKLQRGKS-----NSKGSDQSPSGLNNVFVGATSSLWNSQDHHSSSSSSSS--------------ASSRGRDH---HQQQHHQQQQQNHGSDHGASYRSDGKSPHLTNHDAKSLTDDLDRMQDLKGWASRLSPISP--------------------------------ILGLSMILGVGYLGPWPG----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IP70-1", "uniprot_id": "Q8IP70_DROME", "id": "Q8IP70-1", "name": "", "aln": "-----------------MAMAGPHRLPRPHTRRRFRLQAEFN------------VRQLAITIIATAAVTMLMTATPTLAEIPSKG---------------------------------------------KHTRLDTQQTAQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVA-----------WVRVDTQT-----ILSIHHNVISQNSRISLTYN-----DHRSWYLHIKEVEETDRGWYMCQVNT-DPMR-SRKGYLQVVVPPIIVEG--LTSNDMVVREGQNISLVCKARGYPEPYVMWRREDGEEMLIG------GEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPS-ISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTER---------------GDMIISDTSRAGDKYETTSTVSG-YTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTP-------TT----------AIISEMSLLNRSYDGKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNGDNNQTPVRNPPGAFHNSAGSLAQHNLLAKIMLGIKTQSFGIFKRLSSSLPLAAGQSFLWLSTLSLVSAPSRWRMSNVENRPNSPETVVNNDTAAECWETRSHCVSESNNNNNSRITQRPPMWARHLRIFHIAHTPCGASTQYQRLCERQWQWQRLWQWQCQWKWQHQWQWPMLICIVILAGCFVRWLPMLLHFIGRHIGTFSISATHRQHLMCTFWDNRGNKVVAKNTTPARPSTFEMLCSRMFSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF0-1", "uniprot_id": "Q9VLF0_DROME", "id": "Q9VLF0-1", "name": "", "aln": "-----------MLPPSWHLIGALLVLAATAGDSTNKIILPQILNGGGGGGGVGTAQGKHPSGSKTVATGVVPNFGGAAGNGAGGGGPVAGSG------------------------TGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVA-----------WMHFEQSA-----ILTVHNHVITRNPRISVTHDK--HDRHRTWYLHINNVHEEDRGRYMCQINT-VTAK-TQFGYLNVVVPPNIDDS--LSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINK-----NHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPT-VSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGE---------------GPIIHD----SHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPP-------------------TTASSGIYSTDTHWGENGIN-----------------------NNYAYGGPDSTRSIYAQ-------DKNTRYQSNLNEIGLSEQKSFLDKTQNPLLANGNAN--------------------------------------------EADAESNGARGHNPSMAIAWLFVVIATLLLTIRSAVGSSHS-----------------------------------LSLC---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NGN9-1", "uniprot_id": "IGLO5_HUMAN", "id": "A6NGN9-1", "name": "IgLON family member 5", "aln": "--------------------------------------------------------------MPPPAPGARLRLLAAA-ALAGLA----------------------------------------------------VISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVT-RVA-----------WLNRSN-------ILYAGNDRWTSDPRVRLLIN-----TPEEFSILITEVGLGDEGLYTCSFQT-RHQPYTTQVYLIVHVPARIVN----ISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDG---------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSAR-TALGRAALLRCEAMAVPPADFQWYKDD------------------------RLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPG---------------------------------------------------------------------------------------SLENSAPRPPGLLALLSALGWLWWRM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8HW98-1", "uniprot_id": "IGLO5_MOUSE", "id": "Q8HW98-1", "name": "IgLON family member 5", "aln": "--------------------------------------------------------------MPPPAPGARLRLLAAA-ALAGLA----------------------------------------------------VISRGLLSQSLEFSSPADNYTVCEGDNATLSCFIDEHVT-RVA-----------WLNRSN-------ILYAGNDRWTSDPRVRLLIN-----TPEEFSILITQVGLGDEGLYTCSFQT-RHQPYTTQVYLIVHVPARIVN----ISSPVAVNEGGNVNLLCLAVGRPEPTVTWRQLRDG---------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSAR-TALGRAALLRCEAMAVPPADFQWYKDD------------------------RLLSSGSAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPG---------------------------------------------------------------------------------------SLENSAPRPPGPLTLLSALSWLWWRM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LA63-1", "uniprot_id": "A0ABK0LA63_RAT", "id": "A0ABK0LA63-1", "name": "", "aln": "--------------------------------------------------------------LWTNAVWP-LRLSASGRQLTSTT----------------------------------------------------DLLPGLLSQSLEFSSPADNYTVCEGDNATLSCFIDEHVT-RVA-----------WLNRSN-------ILYAGNDRWTSDPRVRLLIN-----TPEEFSILITQVGLGDEGLYTCSFQT-RHQPYTTQVYLIVHVPARIVN----ISSPVAVNEGGNVNLLCLAVGRPEPTVTWRQLRDG---------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSAR-TALGRAALLRCEAMAVPPADFQWYKDD------------------------RLLSSGSAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPG---------------------------------------------------------------------------------------SLENSAPRPPGPLTLLSALSWLWWRM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15364-1", "uniprot_id": "AMAL_DROME", "id": "P15364-1", "name": "Protein amalgam", "aln": "----------------------------------------------------------------MARLRLLIGLIFCLA-----------------------------------------------------------ISLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVS-----------WAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAEN---TPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGG---------HLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQP-DKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNG---------------------VPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQTVIP----------------------------------------------------------------------------------------------------VPSLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : * : . :. * . : : * : : : * : * * * *.. . : : *. : . . ** . * * . * * * : * : . * : : * . . * *:: *. . .: . : :.: * : : * * . * : . . . * * * : * * .. ::* ", "identical_positions": 32, "similar_positions": 57, "identity": "3.95%" }, { "cls_id": "homologset.agr.HGNC:346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q75NT5-1", "uniprot_id": "AHRR_RAT", "id": "Q75NT5-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "MMIPSGECTYAGRKRRK-PIQKRRLTMGTEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSP---EDHSSR------GFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADT-DNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAP-VLPSVTEMKMKSAFLKAKHRAD-IVVTMDSRAKAVTSLCESELH---------------PKLNYLAGRSNGENVISLFRGQTDRSHWTRALARSSCLCLRGGPD-LLDPKGTSGD----------------------------REEDDQKHILRRSPGARGQREMHKYSYGLETPVHLRHLDWSTEQRSQEGTTKLTRQPSKSEP-STCLVPHGSCVPYPGSQGMFSASNMASFRESLDHPTGTYCSQMN------------------------------------------RPLPDIHQGQVDPSTCHIPQGSLGSRIPLSGMQCFTARGFSTEDAKLPSLPVNIGTPC--------------------------------------------------------NPVLSLEVPIKME------------------------NESGSQDIVEASTTSCVWLGTGDMT-RRHLVGFPARMHLKTE---------------PDYRQQVCTPHRGHGILGTNPHSRDTVGSCREHAPLYSAHCTCLSP-------EPPHHLFMCSHSESQHPSLDQD--CRAPIVKREPLDS-----------------------PSWAAPG-HVTVPRMFPKNASITVIPSKGSDGIFLP--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1U7-1", "uniprot_id": "AHRR_MOUSE", "id": "Q3U1U7-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "MMIPSGECTYAGRKRRK-PIQKRRLTMGAEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSP---EEHSYR------GFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADT-DNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAP-VLPSVTEMKMKSTFLKAKHRAD-IVVTMDSRAKAVTSLCESELH---------------PKLNYLAGKSNGENGISLFRGQTDRSHWARALARSSCLCLRGGPD-LLDPKGTSGD----------------------------REEEDQKHILRRSPGAWGQREMHKYSYGLETPVHLRHLNWSTEQRSQESTTKLTRQPSKNEP-STCLVPHGSCVPYPGSQGMLSASNMASFRDSLDHPTGAYCSQMN------------------------------------------RPLSDIHQGQVDPSTCHISQGSLGSRIPLTGMQRFTARGFSTEDAKLPSLPVTIGTPC--------------------------------------------------------NPVLSLDVPIKME------------------------NESGSQDIVEASTTSCLWLGTSDMA-RGHLVGFPARMHLKTE---------------PDYRQQACTPHLGHGMLGTNPYSRDTVGSCREHAPLYSAHCTCLDP-------EPPHHFFMCSHSESQHPSLDQD--CRAPIVKREPLDS-----------------------PSWAAPG-QVTVPRMFPKSASKTVIPSKGSDGIFLP--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9YTQ3-1", "uniprot_id": "AHRR_HUMAN", "id": "A9YTQ3-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "-MIPPGECTYAGRKRRR-PLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLA------GSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRAD-TAATADAKVKATTSLCESELH---------------GKPNYSAGRSSRESGVLVLREQTDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGD----------------------------REEE-QHRMLSRASGVTGRR---------ETPGPTKPLPWTAGKHSEDG-ARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPIS---HPPSPSPSAYSSRTS------------------------------------------RPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMPPGDLC--------------------------------------------------------GPTLLLDVSIKME------------------------KDSGCEGAADGCVPSQVWLGASD---RSHPATFPTRMHLKTE---------------PDSRQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARGRGE-QSCTCRAA--EAAPVVKREPLDS-----------------------PQWATHS-QGMVPGMLPKSALATLVPPQASGCTFLP--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U0D7-1", "uniprot_id": "A0AB32U0D7_DANRE", "id": "A0AB32U0D7-1", "name": "", "aln": "-MIPPGDCLYAGRKRRK-PVQKQKPEKADQKSNPSKRHRDRLNAELDRLASLLPFSAEVITKLDKLSVLRLSVSFLRVKSFFQAVQEKENHSADVSPT---ETRKEV------QPCVVESDLLLQSLSGFALVVSSDGIIFYASSTIIDYLGFHQTDVMHQKVFDYIHVDERQEFRKQIHWAMNP-----GQQ---DTDEDVVTAHLYSAEQ-PDGVSPELTPFLTRCFIARMRCLLDSTSGFLNMQFQGSLKFLQGQRRRTLSGALLPPQLALFCVAVPLVLPSITELRMKSVTVKCKNRSS-GCS--EKRQRAPRGSYDSEDE---------------LRYNWMSTFSQDAS-------------WAYSRKYR----------------GDACK----------------------------TQDEPLNSHVSTSVSS----------------------KLQTDDASWDARCPVALRTDSNEN----------------------------------YQPGSFQKHNY------------------------------------------SVKLRIG------CNSHLQKYEVDD-----------EKRYMMQNEAFNTLP---------------------------------------------------------------------EAAIKTE------------------------QDSDSENGCNAYG--MLWR--------------PDYTQVKTE---------------PEYYDYCSFYQKGKTTVSPYTNGHHKYLCAGVSRPRKCVLYKDLNHSDVPIGNQDGYMFTNEHKNNMQRLAYEFRGHNRVHIIKQEPDDS-----------------------PVWCPEVIQGHVQHNIPANCTVSNVVLKGNPYVHMQ--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIM6-1", "uniprot_id": "E1JIM6_DROME", "id": "E1JIM6-1", "name": "", "aln": "-MSQLGTVYATKRRRRNGKSLKPPPKDGVTKSNPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVLPHIHAHDGYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDIVHQSVYELVHSEDREELQRQLLW-------------------NSFLPADMSSMQLAETLAPDKALYLERSFTVRFRCLLDNTSGFLRLDIRGRIKVLHGQNRKTEE-----PPLALFAYCTPFGPPSLLEIPHKENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMGGYDLVHYDDLAYVASAHQELLKTGASGMIAYRYQKKDGEWQWLQTSSRLVYKNSKPDFVICTHRQLMDEEGHDLLGKRTMDFKVSYLDTGLASTYFSEADQLVVPPSTSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCRSKRKLQQQNQPQTQQTSPLGGQVGSPAPAVAVEYLPDPAAAVAAAYSNLNPMYTTSPYASAADNLYMGSSMPANAFYPVSENLFHQYRLQGAVGGYYTDYPHSGAPASAYVANGFLSYDGYAIASKADEKWQETGKYYSGYSSGYGSPTSTPQQIPLKTPKSSPQVMEVISCSSDGPSPVGGATPNGVGSVTPKVELAGTTAAAAAGQDPYERQTVLMWGTTHSSGVPLNSHGGRTGAGNPASPQRSTPLGNGLGYASANNNNNDLEPATAAKWNGTKELPGKSGSASTPESYQMQHDDSGLYSASSHTTSPQQQQQQQLQQSQRGVGSNVSAPSSSLTSTGTDQQAVHPSSCHQQQQQQQQQHHHAHPHPHSHHHHHHHHHHETAHQHSSEIILTTHHQQQSQQQQQSLAGYPLHHQLVGVGSGSPPPQPPVALSRSPTTLPAVSSLLNGSASAGGASDIPYQQLAIVSAPLVICAEEVGGGVSSIGRKSSKQQQSLQHLQQQQSLQQQQHAIYQQQHHHSQHHPHHQLLYPANITAHTALAYAPPTAGGAYADGSPLLSFSEVTNTLLNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : *:**. * . *********:***:*** ******* ::::***:**:******:**.**:**.: . . . . . : :. ::*::*.** ::::.:* :*:*: :* .******:*::**.::: :* ::*::: :*: * : . : : ..: : :* *.* *.*****.***** ::::* :*.* **.::: . * *:**. .* ** *: :. .:.* : . : : : . ::* . . * . : : : : . . :..... ...: . : : . : :* ..:: . .:. :. * * ::: : : : : * . . . . . : : . : : .:. :* * . :* . ... : ", "identical_positions": 103, "similar_positions": 159, "identity": "9.9%" }, { "cls_id": "homologset.agr.HGNC:3465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNE5-1", "uniprot_id": "ESTD_RAT", "id": "B0BNE5-1", "name": "S-formylglutathione hydrolase", "aln": "--------------------------------------------MELKQISSNKCFGGLQKVFEHSSVELKCKMKFAIYLP-----PQAESAK-CPALYWLSGLTCTEQNFISKSGCQQAASEHGLVVIAPDTSPRGCNIKGE-DDSWDFGTGAGFFVNATEDPWNTNYRMYSYVTEELPQLINANFPVDP-------QRISIFGHSMGGHGALICALK-NPGK-YRSVSAFAPICNPVLCPWGKKAFNGYLGPDQSKWKAYDATCLVKSYSGPQID-ILIDQGKDDEFLSNGQLLPDNFIAACT-EKKIP-VVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0P3-1", "uniprot_id": "ESTD_MOUSE", "id": "Q9R0P3-1", "name": "S-formylglutathione hydrolase", "aln": "--------------------------------------------MALKQISSNRCFGGLQKVFEHSSVELKCKMRFAVYLP-----PQAESGK-CPALYWLSGLTCTEQNFISKSGYQQAASEHGLVVIAPDTSPRGCNIKGE-DDSWDFGTGAGFYVNATEDPWKANYRMYSYVTEELPQLINANFPVDP-------QRMSIFGHSMGGHGALICALK-NPGK-YRSVSAFAPICNPVLCSWGKKAFSGYLGPDESKWKAYDATCLVKAYSGSQID-ILIDQGKDDEFLSNGQLLPDNFIAACT-EKKIP-VVFRLQEGYDHSYYFIATFIADHIRHHAKYLNA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10768-1", "uniprot_id": "ESTD_HUMAN", "id": "P10768-1", "name": "S-formylglutathione hydrolase", "aln": "--------------------------------------------MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLP-----PKAETGK-CPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGE-DESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDP-------QRMSIFGHSMGGHGALICALK-NPGK-YKSVSAFAPICNPVLCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLD-ILIDQGKDDQFLLDGQLLPDNFIAACT-EKKIP-VVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KSB5-1", "uniprot_id": "Q7KSB5_DROME", "id": "Q7KSB5-1", "name": "S-formylglutathione hydrolase", "aln": "MGRNFLRLPSVSGRSSFVYSIVACSNLPKRRSIVLSFGHIMTENMTLEQLSANKCFEGEQRVYRHRSDTLKCDMTFGVFLP-----PAALEGKPCPVLFFLSGLTCTHENFIQKSGFQQHAARHNLIVVNPDTSPRGVEIAGQ-DDAYDFGSGAGFYVDAKEEPWSKHYKMYSYVTQELVDVVNANLPVVP-------GKRGIFGHSMGGHGALICALK-NPGL-YQSVSAFAPIANPTECPWGKKAFAGYLGSNPDDWALWDATHLVSQYESTPQE-LFIDQGAADNFLAGKQLLPENLLAAADGNDHIQ-TIFKQREGYDHSYFYIATFVAEHIAYHAALLTASA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40363-1", "uniprot_id": "SFGH_YEAST", "id": "P40363-1", "name": "S-formylglutathione hydrolase", "aln": "----------------------------------------------MKVVKEFSVCGGRLIKLSHNSNSTKTSMNVNIYLPKHYYAQDFPRNKRIPTVFYLSGLTCTPDNASEKAFWQFQADKYGFAIVFPDTSPRGDEVANDPEGSWDFGQGAGFYLNATQEPYAQHYQMYDYIHKELPQTLDSHFNKNGDVKLDFLDNVAITGHSMGGYGAICGYLKGYSGKRYKSCSAFAPIVNPSNVPWGQKAFKGYLGEEKAQWEAYDPCLLIKNIRHVGDDRILIHVGDSDPFL-EEHLKPELLLEAVKATSWQDYVEIKKVHGFDHSYYFVSTFVPEHAEFHARNLGLI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. * * * : .* . ::** * *.:::******* :* .*: : * .:.: :: ******* :: .: : ::*** ****:::*.::*: :*:**.*: :** : ::::: . .* ******:**: ** .* *:* ****** ** .**:*** **** : .* :*. *:. : ::*. * * ** :* *: :: * . . :: .*:****::::**:.:* .** * ", "identical_positions": 93, "similar_positions": 84, "identity": "26.8%" }, { "cls_id": "homologset.agr.HGNC:3466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97682-1", "uniprot_id": "ESM1_RAT", "id": "P97682-1", "name": "Endothelial cell-specific molecule 1", "aln": "MKSLLLLTTLLIPLHLGMAWSAKYAVDCPEHCDNTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVSGMDGVKCGPGLKCHFYSEEDDFGDEFGVCKDCPYGTFGMDCKETCNCQSGICDRVTGRCLDFPFFQYAAAKSPSRTSASQTERDAASGDGNAVREEIGDRNAARPSVM-KWLNPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYY7-1", "uniprot_id": "ESM1_MOUSE", "id": "Q9QYY7-1", "name": "Endothelial cell-specific molecule 1", "aln": "MKSLLLLTTLLVPLHLGMAWSAKYAVDCPEHCDKTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVSGMDGVKCGPGLKCHFYSEEDDFGDEFGICKDCPYGTFGMECKETCNCQSGICDRVTGRCLDFPFFQYAAAKSPSRTSASHTERDSASGDGNAVREEIGEGNAARPSVM-KWLNPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ30-1", "uniprot_id": "ESM1_HUMAN", "id": "Q9NQ30-1", "name": "Endothelial cell-specific molecule 1", "aln": "MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNR-FVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*******:* ** *** :******:***.:**:** *************:***** *************:******:*: . ** **:***:***********:*:************ **:**.******:.:**..* .* **:* ****** ****: . *** ..** ******", "identical_positions": 136, "similar_positions": 29, "identity": "73.51%" }, { "cls_id": "homologset.agr.HGNC:3467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06211-1", "uniprot_id": "ESR1_RAT", "id": "P06211-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPAVFNYPEGAAYEFNAAAAAAAAGASAPVYGQSSITYGPGSEAAAFGANSLGAFPQLNSVSPSPLMLLHPPPHVSPFLHPHG------HQVPYYLENEPS---AYAVRDTGPPAFYRSNSDNRRQNGRERLSSSSEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYM-CPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGTSGDMRAANLWPSPLVIKHTKKN--SPALSLTADQMVSALLDAEPPLIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKINDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAP--ASRMGVPPEEPSQSQLTTTSSTSAHSLQTYYIPPEAEGFPNTI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19785-1", "uniprot_id": "ESR1_MOUSE", "id": "P19785-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPTVFNYPEGAAYEFNAAAAAAAA-ASAPVYGQSGIAYGPGSEAAAFSANSLGAFPQLNSVSPSPLMLLHPPPQLSPFLHPHG------QQVPYYLENEPS---AYAVRDTGPPAFYRSNSDNRRQNGRERLSSSNEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYM-CPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGASGDMRAANLWPSPLVIKHTKKN--SPALSLTADQMVSALLDAEPPMIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAP--ASRMGVPPEEPSQTQLATTSSTSAHSLQTYYIPPEAEGFPNTI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03372-1", "uniprot_id": "ESR1_HUMAN", "id": "P03372-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQ-----VYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHG------QQVPYYLENEPS---GYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYM-CPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN--SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAP--TSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57717-1", "uniprot_id": "ESR1_DANRE", "id": "P57717-1", "name": "Estrogen receptor", "aln": "----MYPKEE------HSAGGISSSVN---------------YLDG----AYEYPN-PTQTFGTSSPAEPA----------SVGYYPAP-----PDPHEEHLQTLGGGSSSPLMFAPSSPQLSPYLSHHGGHHTTPHQVSYYLDSSSSTVYRSSVVSSQQAAVGLCEELCSATDRQELYTGSRAAG--GFDSGKETRFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYV-CPATNQCTIDRNRRKSCQACRLRKCYEVGMMKGGIRKDR-GGRSVRRERRRSSNEDRDKSSSDQCSRAGVRTTGPQDKRKKRSGGVVSTLCMSPDQVLLLLLGAEPPAVCSRQKHSRPYTEITMMSLLTNMADKELVHMIAWAKKVPGFQDLSLHDQVQLLESSWLEVLMIGLIWRSIHSPGKLIFAQDLILDRSEGECVEGMAEIFDMLLATVARFRSLKLKLEEFVCLKAIILINSGAFSFCSSPVEPLMDNFMVQCMLDNITDALIYCISKSGASLQLQSRRQAQLLLLLSHIRHMSNKGMEHLYRMKCKNRVPLYDLLLEMLDAQRFQSSGKVQRVWSQSEKNPPSTPTTSSSSSNNSPRGGAAAIQSNGACHSHSPDP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15370-1", "uniprot_id": "EGON_DROME", "id": "P15370-1", "name": "Protein embryonic gonad", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQLCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCKHNGDCVINKKNRTACKACRLRKCLLVGMSKSGSRYGRRSNWFKIHCLLQ---EQQTTSGLGGGSSVGSGSGG--------------GVSSASLEQLARLQQASNQARQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPSFLQAAKLHHQRQLKLDSRLSNTPSDSGASSAGDPN-----------------EDGVTSVLGGQIATPSSTNATSLPKLDLRHPNFPATSEPDADMQRQRHQELLEIFRSHSEPLYSSFAPFSHLPPVLLAAGVPQLPIFKDQFKAELLFPTTSSPELEEPIDLSFRSRADPASPMAHNSNSPSLSEP-----------AAASHCLGESTNFVRKSTPLDLTLVRSQTLTG------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * **.: *:*:*:*.::*****:** *: :. * ..:*.*:::.*.:*:******* *** *.* * .* .. : : * : . .. . :. :. : : * *. : . :.* : : ..: . : * . . : .**.* :* : *. . * *. :*:..::. :** : . .* :: : :... . : * * . .: : . : * : : : *. :*. :. :. . . : . :: : . : . :* .:: ", "identical_positions": 56, "similar_positions": 114, "identity": "9.06%" }, { "cls_id": "homologset.agr.HGNC:3468", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62986-1", "uniprot_id": "ESR2_RAT", "id": "Q62986-1", "name": "Estrogen receptor beta", "aln": "MEIKNSPSSLS--SPASYNCSQSILP--------LEHGPIYIPSSYVDNRHEYSAMT---FYSPAVMNYS-VPGSTSNLDGGPVRL---STSPNVLWPTSGHLSPLATHCQSSLLYAEPQ-KSPWCEAR----SLEHTLPVNRETLKRKLSGSSCASPVTSPNAKRDAHFCPVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGS--------RRERCGYRIVRRQR------SSSEQVHCLSKAKRNGGHAPRVKELLLST----------LSPEQLVLTLLEAEPPNVLVSRPS-MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSS-MYPLASANQEAESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRG----------------------YKSSISGSECSS-TEDSKNKESSQNLQSQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08537-1", "uniprot_id": "ESR2_MOUSE", "id": "O08537-1", "name": "Estrogen receptor beta", "aln": "MEIKNSPSSLT--SPASYNCSQSILP--------LEHGPIYIPSSYVESRHEYSAMT---FYSPAVMNYS-VPSSTGNLEGGPVRQ---TASPNVLWPTSGHLSPLATHCQSSLLYAEPQ-KSPWCEAR----SLEHTLPVNRETLKRKLGGSGCASPVTSPSAKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGS--------RRERCGYRIVRRQR------SASEQVHCLNKAKRTSGHTPRVKELLLNS----------LSPEQLVLTLLEAEPPNVLVSRPS-MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTARFRELKLQHKEYLCVKAMILLNSS-MYPLATASQEAESSRKLTHLLNAVTDALVWVISKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRG----------------------YKSSISGSECCS-TEDSKSKEGSQNLQSQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92731-1", "uniprot_id": "ESR2_HUMAN", "id": "Q92731-1", "name": "Estrogen receptor beta", "aln": "MDIKNSPSSLN--SPSSYNCSQSILP--------LEHGSIYIPSSYVDSHHEYPAMT---FYSPAVMNYS-IPSNVTNLEGGPGRQ---TTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQ-KSPWCEAR----SLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGS--------RRERCGYRLVRRQR------SADEQLHCAGKAKRSGGHAPRVRELLLDA----------LSPEQLVLTLLEAEPPHVLISRPS-APFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSS-MYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRG----------------------CKSSITGSECSP-AEDSKSKEGSQNPQSQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B359-1", "uniprot_id": "A0A8M2B359_DANRE", "id": "A0A8M2B359-1", "name": "", "aln": "MSSSPGPAPVLDSSKADRGASPALLPRLYASPLGMDNQTVCIPSPYVEACQDYSPPHGGEFNHGALTLYSPVSSAVLGFHRPPVSESLVPLSPTILWP------PHSLHCPPPLAYSETRSHSAWEEAKTHTLSQSSSVLSHTKLLGQQLEGDNGLNPSASIVGKGDTHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKSRRKSCQACRLRKCYEVGMMKCGMQLTLRFCVRRERCSYRGARHRRNPQIRDSSGGVVGLRGQSQQHLEFPLSPSQHLFPSGGRAEGRGLNYSPEQLVSCILEAEPPQIYLREPVKKPYTEASMMMSLTSLADKELVLMISWAKKIPGFVELTLSDQVHLLECCWLDILMLGLMWRSVDHPGKLIFTPDLKLNREEGNCVEGIMEIFDMLLATTSRFRELKLQREEYVCLKAMILLNSNNCSSLPQTPEDVESRGKVLNLLDSVTDALVWIISRTGLSSQQQSIRLAHLLMLLSHIRHLSNKGIEHLSNMKRKNVVLLYDLLLEMLDANTSQSSRMLEDRQQSPENLHTSRPQPDLKDSDQETPHSPRAEETVNKTLHSSLLREDMDTN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . .*:.: * :. ..* ::** ::: .: ***.**: ::*.. * *: ** :.. . .:. * . **.:*** * * . *:*.: :*.* **: * . :: : : * ::: *. .* :. .* *:***.** ******************************************.******************:*** *****.** .*::* *:. : .:::: .. : *: : ****** :******:: : .* *:**********.******* **.***********:* ***:***.**:::**:******:********:*** *:*:**:*****:**********:********::**:*:********. .* : ::.:* *: :**::*******:*:::*:******:***:*******:** ****:*** .** **** :********:*:. :. *.* : .. :*:: .* .. : ", "identical_positions": 283, "similar_positions": 139, "identity": "46.7%" }, { "cls_id": "homologset.agr.HGNC:347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFP9-1", "uniprot_id": "A0ABK0LFP9_RAT", "id": "A0ABK0LFP9-1", "name": "", "aln": "MQLVDVHSTRDLWLSQAFLPSISPRPELCIFTSSQMEKEEETTRELLLPNWQGSGSHGLTIAQRDDG-VFVQEVMQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGD-----RSPEPGQTWA-HEVFSSRSSEVVLSGDDEDYQRIYTTKIKPRLRSEDGVEGDLGETQSRT---------ITVTRRVTAYTVDVTGREGVKDIDISSPEFMIKIPRHEVTEISNTDVETQPGKTVIRLPSG------SGAASPTTGSAVDIRAGAISASGPELEGAS---------------------------HSKFQVTVPG-------TKVGSLDVNVKAKGLDLGGKGG-------------------------------------------------IQVPGVDVSSSLGGGS------------------VEGQGPSLQSGDIG-KVKIPTMK--------------------------------------MPKFGVS-AGLEGQIPEGGLNVSAPEFSVG-----------------------------------------------------------HKGDKPGLAIGG------------NIQAPHLEVSTSSVNIEGLEGKLKGPQITGPSLKGDLGLKG--TKLQGNIGMDDACASKIEGSITGPCVEIGTP-----------------------------DVDVHGLGGKLN-----VPKFSASGSKGEGVGIDVALP----TGKVTLPGVSGDVNLPEIATGGLEG----------KMKGAKVKTPEMIVQK----------------------------------------PKISMQDVDLSLGSCKLKGNMKVSAPEVKGGVKGPQVAVKGFGVDTETPNLEGTLTGPKLSSPSGKIGTCRISMADVDLNVAAPKGKG--GIDVTLPKVEGKVKGPEVDVKGPKTDISAPGVEVHGPEWNLKMP-----KFSIPGVKGEG----ADVNVPLAKGDISLSGPKVNVEAPDVNVEGLGGKLKGPDINLPEGSVKTPKISMPDVDLHIKGPKVKGEYDVTTPKLEGELKGPKVDTDIPQVDVHGP--NLKIPKMKMPKFSVPGFKAEGPEVDVNLPKVDIDISGTKVEVSAPDVSIEGPEGKLKGHKFKMPEMNIRAPKISMPDVDLHLKGPNVKGEYDVTVPRAEGEIKVPDVELKSAKVDIDVPN--------------------------------------------------------VDAQGPELHMKMPTIKMPKFGMPGFKAESPEVEMNLPKADIDVSGPKVDVKVPDVNTEGLEGKLKGPKLKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDVTMPKLEGDLKGPKVDVSAPDVDVHGPDWNMKMPKIKMPKFTMPSLKGEGPELDVSMPKADVDISVPKLDISAPDLNLEGPEGKLKGPKFKMPEMHFKAPKMSLPDVDLDLKGPKMKGNVDMSAPKIEGEMKVPDVDIKGPNVDVQS-------PDWSLKMPKMKMPKFSMPTLKGEGPDVDVSLPKATIDVSGPKLDIETSDVSFEGPEGKLKGPKFKMPDMHFKAPKISMPDVDLNMKGPKVKGDMDVAVPEIEGKMKVPDVDIKGPKVDVDAPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLSKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKVKGDMDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMHFKAPKISMPNIDLNLKGPKVKGDMDVAVPEIEGEMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVN--------------------------------------------------------------------------IEGPDAKLKGPKFKMPEMNIKPQKISMPDVSLNLKGPKAKAEYDVSVPKVGGEIKAPAVDLKGP--KVEAPDVEVHGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVNLQKANIDVSGPKMDIDVPDVNIEGPEGKLKGPKFKMPSMSIQTHKISMPDVGLNLKGPKLK---------------------------------------------------------------------------------------------------------------------------------------------SGVDVSLPKVEGDLKGPEVDVDVGDVDIECPEGKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVAVPEIEGEMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIEVPDVNIEGPEGKLKGSKFKMPKLNIKAAKISMPDVDLNLKGPKLKGEIDASVPEMEADLRGPQIDVKGP-----------------------------SVDVEVP--DVDLECPEAKLKGPKFKMP-----------DMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELK-------------------------------------------------------------GPSVDVDVPDVDLECPEAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELKGP-------SVDVDVPDVDLECPEAKLKGPKFKMPDMHFKAPKISMPDVDFNLKGPKIKGDIDVSVPKLEGELKGPELDVKSPKLDANIPEVAVEGPEGKWKSPKFKMPDMHFKAPKISMPDIDLHLKSPKIKGDVDVDVPKLEGDLKGPNVDMSGP-------------------------------------------------------------DVEIEGPEGKLRGPKFKMPDMNIKAPKISMPDIDLHLKGPKVKGDVDASLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGP-------------EVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDVDVPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGQKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKTPKISMPDLNLNLKGPNVKGDVDVSIPNVEGDLQGPSLDIKSPKLDVN---------------------------------------------------APDIDIHGP---------------------------------------------------------EGKLKGPKLKMPDMHVNMPKISMPDIDLNLKGSKVKGDVDISGPKLEGDIKTPKVDVKGPELDISASKVNIDAKG---KKSRFKLPKFNFSGSKVQTPEVDVKLKKPDVDVTAPKVDINAPEVEVQG---KVKGPKFKMPFLSISSPKVSMPDVELNLKGPKVKGELDATVPNLEGDFKSPKVDIKAPDVQLNAPDVDVHGQEWNLKMHKMKMPKFSVSGVKAEGPDVAVDLPKGDINIEGPSMNIEGPELNVECPEGSLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKMDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLSKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLHLKGPKIKGDVDVSLPKVEGDLEGPHVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDINAPD--------------------------------------------------------VDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVQGPDWHL--------------------------------------------------------KMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGP-----KVDID---------------------------------------------------VPDVDVQGPDWH-----LKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDID---------------------------------------------------VPDVDVQGPDWH-----LKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVTGPKVDIDVPDVNVGGPDVKVKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDASLPKME-----------GPGVDIDSPDVNIEGPEGKLKGPKFKMPDMHIKAPKISMPDFDLNLKGSKVKGDVDLSLPKVEGDLKG-------PEIDIECPEGKLKGPKFKMPDVHFKTPQISMSDIDLNMKGPKVKGDMDISVPKLEGDLKGTKVDVKGPKMDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPDVDLNLKGPKVKGDVDISLPKVEGDLKGPEVDIKGPKVDINAPDVDVQGP-------------------DWHLKMPKVKMPKFSMPGF-----KAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKMDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLHLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDVDVPD--------------------------------------------------------VDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNVDGPDMKVKGPKFKMPEINIKAPKISMPDVDLELKGPKVKGAFDGS---VPKIEGTLKGPEIDMKGPGLDFEGPDAKLSGPNLKMPSLEVPVPKISGPDANVHLKTPNVGISGPKLGGGEVDLRGPKVDLETPSLDVHMESPDINIEGPDVKVPKFKKPKFGFG---AKSPKADIKTPTVDVTVPEAELSVETPEINIGGKGKKSKFKMPKIHMSGPKVKTKKQGFDLN---------VPGGEIDASLKVPDVDVS-----VAGPDAALK-AEVKSPKVKKTMFGK----MYFPDVEFDIKSPKFKAEAALPSPKLEGEIKVPDVDISSPGVNVEAPDIHVKAPKFKVPGVEAAGPKIEGNLKGPKVQAN----------LDTPDINIQGPEAKIKTPSFS---VSAPQVSIPDVNVKLKGPNIKGDVPSVG------LEGPDVDLQGPEGKIKFPKFSLPKISAPGVKMGGG-STEIHAQMPSLEAGLSTSDIKFEGPGVSLKGPGVDLPSVDLSLPKVSGPDL---DLNLKGPSLKGDVAASSP--SMKLHAPGLDMKGVAGKVQIGADGVKVSGTDATAALSVGAPDVTLKGSSLQGDLAVSG-DIKCPKVSVGTPEVSVEALEG---GVKLPQMKLPQFGISTPGSDLDINIKGPQVCGELQG-----SGTDVNLKGPQISAPGMDFNLEGPKVRGSLGATG-ELKGPSIGGGLPG--------------------ISIQGPEGNLQMPGIKASGCDVKVS----------SGQISGPEIKG------DLKGSGIGLHGAVPDLSVKGPSFNMASPESDFG--------VSLKGPKVKG-GVDVSGG-VSVPDINLGEGHMNVKGFGGEWK--------GPQVSSSVNLDTTKLVG-----NLHFSGPK-------IEGDVKGGQIGLQGPGLSVSGPQ---GHLESGSGKVTFPKMKIPKFTFSGRELTGREVGVDVNFPNVEANVQAGAGEGELEESAVKLK--KSKIKMPKFTFSKPKGKGG----VTGSPEASVSGSKGDLKSSKASLGS----LEGEAEAETSS-----PKGK-FSLFKSKKPRNRSNSFSDEREFSAPSTPTGTLEFAGGEG---------KGKHGKLKFGTFGGLGSKSKGHYEVTGSDDEAGKLQGSGVSLASKKSRLSSSSSNDSGTKLGIQLPEVEISVSTKKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q616-1", "uniprot_id": "E9Q616_MOUSE", "id": "E9Q616-1", "name": "", "aln": "-----------------------------------MEKEEETTRELLLPNWQGSGSHGLTIAQRDDG-VFVQEVMQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGD-----RSPEPGQTWT-HEVFSSRSSEVVLSGDDEDYQRIYTTKIKPRLRSEDGVEGDLGETQSRT---------ITVTRRVTAYTVDVTGREGVKDIDITSPEFMIKIPRHEVTEISNTDVETQPGKTVIRLPSG------SGPASPTTGSAVDIRAGAISASGPELEGAG---------------------------HSKFQVTVPG-------AKVGSLDVNVKAKGLDLGGKGG-------------------------------------------------IRVPGVDVSSSLGAGS------------------VEVQAPSLQSGDIG-KIKIPTMK--------------------------------------VPKFGVS-AGLDGQIPEVGLSVSAPESSVG-----------------------------------------------------------HKGDKPGLAIGG------------NIQAPHLEVNPSSVNIEGLEGKLKGPQITGPSLEGDLGLKG--TKLQGNIGMD-ACASKIEGSITGPSVEIGTP-----------------------------DVDVHGLGGKLNMPKMKVPKFSASGSKGEGIGLDVALP----TGEVTLPGVSGDVSLPEIATGGLEG----------KMKGAKVKTPEMIIQK----------------------------------------PKISMQDVDLSLGSCKLKGNMKTSAPEVKGDVKGPQMAVKGSRVDIETPNLEGTLTGPKISSPSGKIGACRISMADVDLNVAAPKGKG--GVDVILPNVEGKAKGLEVDVKGPKMDISAPDVEVHGPEWNLKMP-----KFSVPGVKGEG----LDVNVTLPEGDISISGPKVNVEAPNVNMEGLGGKLKGPDINLPEVSVKTPKISMPDVDLHIKGPKVKGEYEVTPPKLEGELKGSKVDIDTPQVDVHGP--DLKIPKMKMPKFSVPGFKAEGPEVDVNLPKADLDISGTKVEVSAPDVSIEGSEGKLKGHKFKMPEMNIRAPKISMPDVDLHLKGPNVKGEYDVTVPRAEGEIKVPDVELKSAKLDIDVPN--------------------------------------------------------VDVQGPELHMKMPKIKMPKFGMPGFKAESPEMEVNLPKSDIDVSGPNVDVKVPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDVTMPKLEGDLKGPKVDVSVPDVDVHGPDWNLKMPKIKMPKFSMPSLKGEGPELDVNMPKADVDISVPKLDISAPDLNLEGPEGKLKGPKFKMPEMHFKAPKVSLPDVDLDLKGPKMKGNLDMSAPKIEGEMKAPDVDIKGPNVDIKAPEVDVQGPEWSLKMPKMKMPKFSMPTLKGEGPDVDVSLPKATIDVSGPKLDIETSDVSLEGPEGKLKGPKFKMPDMHFKAPKISMPDVDLNMKGPKVKGDMDVTVPKIEGEMKVPDVDIKGPKVDISAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGP--EVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKVKGDVDVSLPKVEGDLKGPDIDIKGPKMDINAPDMDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIEAPDVSIEGPEGKLKGPKFKMPDMHFKAPKISMPDVDLNIKGPKGKADVDASLPEVEGGVKVPDVDIKGPKVGIDAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDI--PKANIDVSGPKVDIDVPDVN--------------------------------------------------------------------------IEGPDTKLKGPKFKMPEMNIKPQKISMPDVSLNLKGPKVKADCDVSVPKVGGEIKAPAVDIKGP--KVEAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGAEVDVNLQKANIDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKGPKLK---------------------------------------------------------------------------------------------------------------------------------------------SGVDVSLPKVEGELKGPEVDVDVGDIDIECPEGKLKGPKFKMPDMHFKTPKISMPDVDLHLKGPKVKGDMDVTMPKIEGEMKVPDVDIKGPKVDINAPDVDVRGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDLDIEGPEGKLKGSKFKMPKLNIKAAKISMPDVDLNFKGPKLKGEIDASVPEMEADLRGPQVDIKGT-----------------------------NVDVKVP--DVDLECPDAKLKGPKFKMP-----------DMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELK-------------------------------------------------------------GPSVDVEVPDVDLECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELKGP-------SVDVEVPDVDLECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVTVPKLEGELKGPSVDVEVP-------DVDLECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKIEGEMKVPDVDIKGPKVDINAPDVDVRGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPDMHFKAPKISMPDVDFNLKGPKIKGDIDVSVPKIEGELKGPELDLKGPKLDANIPEVAVEGPEGKWKSPKFKMPDMHFKTPKISMPDIDLHLKSPKIKGEVDVDVPKLEGDLKGPNVDMSRPDIEIEGPEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDISLPKVEGDIKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKIKMPKFSMPGFKGEGPEVDVSLPNADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLHL--KGPKVKGDVDVSLPKVEGDLKGPDVDIKGPKMDIN---------------------------------------------------APDMDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEV---DVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEVNIKAPKISMPDLNLNLKGPNVKGDVDVSIPNIEGDLKGPSLDIKSPKLDVNAPDIDVHG------------------------------------------------------PEGKLKGPKLKMPDMHVSMPKISMPEIDLNLKGSKVKGDVDISGPKLEGDIKVPRVDLKGPEVDISAPKVNIDG---KAKKSRFKLPKFNFSGSKVQTPEVDVKLKKPDVDITAPKVDINAPEVEVQG---KVKGSKFKMPFLSISSPKVSMPDVELNLKGPKVKGDLDAAGPNLEGDFKGPKVDIKAPDVQLNAPDVDVHGPEWNLKMPKMKMPKFGVSGIKAEGPDVAVDLPKGDINIEGPSMNIEGPELNVECPEGSLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVSLPKANIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHL--------------------------------------------------------KMPKIKMPKFSMPGFKGEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKDPKVDIDVPDVDVHGPDWHLKMPKIKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKVKGDVDVSLPKVEGDLKGPDVDIKGP-----KMDIN---------------------------------------------------APDMDVQGPDWH-----LKMPKMKMPKFSMPGFKAEGPEVDVNLPKVDLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKMDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIEGPNVNIEGPEGKLKGPKFKMPDLHLKAPKISMPEIDLNLKGPKLKGDVDVSLPKVEGDLKGPEVDIKGPKVDIS---------------------------------------------------APDMDVHGPDWH-----LKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDASLPKMEGELKGPGIDIKCPTVDIDTPDVNIEVPEGKLKGPKFKMPDMHIKAPKISMPDFDLNLKGPKVKGDVDLALPNVEGDLKG-------PEIDIEGPEGKLKGPKFKVPDVQFKTPQISMSDIDLNVKGPKIKGDLDISIPKPEGDLKGPKVDIKGPKLDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDISAPDVDVHGP-------------------DWHLKMPKVKMPKFSMPGF-----KGEGPEVDVSLPKANIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGP------------------------------------------------------------------------KVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNVEGPDMKVKGPKFRMPEINIKAPKISMPDVDLELKGPKVKGAFDGS---VPKIEGTLKGPEIDMKGPGLDFEGPDAKLSGPNLKMPSLEVSVPKITGPDANVHLKTPKVGISAPKLGGGEVDLKGPKVDLETPSLDVHMESPDINIEGPDVKVPKFKKPKFGFG---AKSPKADIKTPTVDVTVPEAELNVDSPEINIGGKSKKSKFKMPKIHMSGPKVKAKKQGFDLN---------IPGGEIDTSLKAPDVDVS-----VAGPDAALK-AEVKSPKVKKTMFGK----MYFPDVEFDIKSPKFKAEAPLPSPKLEGEIKVPDVDISSPGINVEAPDIHMKAPKFKVPGVEASGPKIEGNLKGPKVQAN----------LDTPDINIEGPEAKIKAPSFS---VSAPQVSIPDVNVNLKGPKIKGDVPSVG------LEGPNIDLQGPEGKIKFPKFSLPKISAPGVKMEGG-STEIGAQMPSLEGGLSTSDMKLEGPHLSLKGPGVDLPSVDLSMPKVSGPDL---DMNLKGPSLKGDLGASSP--SMKLHAPGLDLKGVGGKVHIGADGVKMSGIDATTALSVGAPDVTLKGPSLQGDLAVSG-DIKCPKVSVATPDVSLEASEG---AVKLPHMKLPQFGISTPGSDLDINIKGPQVCGELKG-----SGMDVNLKGPQISAPSMDFNLEGPKVKGSLGAAG-ELKGPAIGGALPG--------------------ISIQGPEGNLQMPGIKASGCDVKLS----------SGQISGPEIKG------DLKGSGLGLHGAVPDIGVKGPSFNVASPESDFG--------VSLKGPKVKG-GVDVSGG-VSVPDINLGEGHMSVKGSGVEWK--------GPQVSSSLNLDTSKLAG-----NLHFSGPK-------IEGDVKGGQTGLQGPGLSVSGPQ---GHLESESGKVTFPKMKIPKFTFSGRELIGREVGVDVNFPKVEANVQAGAGEGKWEESEVKLK--KSKIKMPKHIFSKSKGKGG----VTGSPEASISGSKGDLKSSKASLGS----LEGEVEAEASS-----PKGK-FSLFKSKKPRHRSNSFSDEREFSAPSTPTGTLEFAGGDA---------KGKHGKLKFGTFGGLGSKSKGHYEVTGSDDEAGKLQGSGVSLASKKSRLSSSSSNDSGTKVGIQLPEVELSVSTKKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09666-1", "uniprot_id": "AHNK_HUMAN", "id": "Q09666-1", "name": "Neuroblast differentiation-associated protein AHNAK", "aln": "-----------------------------------MEKEE-TTRELLLPNWQGSGSHGLTIAQRDDG-VFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGD-----RSPEPGQTWT-REVFSSCSSEVVLSGDDEEYQRIYTTKIKPRLKSEDGVEGDLGETQSRT---------ITVTRRVTAYTVDVTGREGAKDIDISSPEFKIKIPRHELTEISNVDVETQSGKTVIRLPSG------SGAASP-TGSAVDIRAGAISASGPELQGAG---------------------------HSKLQVTMPG-------IKVGGSGVNVNAKGLDLGGRGG-------------------------------------------------VQVPAVDISSSLGGRA------------------VEVQGPSLESGDHG-KIKFPTMK--------------------------------------VPKFGVS-TGREGQTPKAGLRVSAPEVSVG-----------------------------------------------------------HKGGKPGLTI----------------QAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKG--AKPQGHIGVD-ASAPQIGGSITGPSVEVQAP-----------------------------DIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLP----TGEVTVPGVSGDVSLPEIATGGLEG----------KMKGTKVKTPEMIIQK----------------------------------------PKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKG--GVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEG----PDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPD--------------------------------------------------------VEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGP------------------------------------SVDVEVP--DVELECPDAKLKGPKFKMP-----------EMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGP-------DIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAP--DVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGP-------------DGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDID---------------------------------------------------VPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDV---DVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHG------------------------------------------------------PDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEG---KSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQG---KVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGP--------------------------------------------------------------------------------------------------------------KVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGP-----KVDIN---------------------------------------------------APDVDVRGPDWH-----LKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDID---------------------------------------------------APDVDVHGPDWH-----LKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKG-------PEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGP-------------------DWHLKMPKVKMPKFSMPGF-----KGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGP------------------------------------------------------------------------KVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVS---VPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGP--KVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFG---AKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLN---------VPGGEIDASLKAPDVDVN-----IAGPDAALK-VDVKSPKTKKTMFGK----MYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQAN----------LGAPDINIEGLDAKVKTPSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVG------LEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDL---DLNLKGPSLKGDLDASVP--SMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG-DIKCPKVSVGAPDLSLEASEG---SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKG-----PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATG-EIKGPTVGGGLPG--------------------IGVQGLEGNLQMPGIKSSGCDVNLPGV---NVKLPTGQISGPEIKG------GLKGSEVGFHGAAPDISVKGPAFNMASPESDFG--------INLKGPKIKG-GADVSGG-VSAPDISLGEGHLSVKGSGGEWK--------GPQVSSALNLDTSKFAG-----GLHFSGPK-------VEGGVKGGQIGLQAPGLSVSGPQ---GHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLK--KSKIKMPKFNFSKPKGKGG----VTGSPEASISGSKGDLKSSKASLGS----LEGEAEAEASS-----PKGK-FSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEG--GKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZ50-1", "uniprot_id": "F1QZ50_DANRE", "id": "F1QZ50-1", "name": "", "aln": "------------------------------------MDDDQDTREVLFPQWMGADKHGLTIEQKGQGEIFVKEVKDESPAAHTGKVHEGDQIVGATIYFDNMSSEETAELLKTLNRHKVGLKLQNKGGDKSPCRSPMGTLSWEGRGSFGGSSSDILLSGDDEDYKRIYSKKIKPRLKSEDLAEGVDVRTERHSSTSSDGCTITTITRRITTYTVDMPGG-TSQQIDPSSPEFKIQLLQHEQEGGDSSQIGLPHSSLVSSEHGGKNLGDISFGGPHVTGSSVKHCSTGSIRATSELDGSGREITINVSDTGLSGGRGQRFTEHFVGTETSLEGNFSGRVTTGLEKQVGNISSPVEASFKALSTKGGTVKGSVLETHGSGFSIIGGSKGSIGRESSSEVLKDGSDDLTKLSKFSIDVQRPKVNIKRSEADISQGSDFAIPDMDSKAKLPKVETSGSVVHSKEIGGEFKLPNVKGSKQFTVESPNVEANFNNQNLKDVSQRGFSLTGNQDLPHPSFRMKGTNLEDSNLGADMDISGPEFQVQRCEIKVKDTQFDVPSVTGQGISISDVDLTLKEQKRGVNVCVQNIESNVMTPKVEIKGQSLKGVEDGFMMKGPNIDANAANAKIEIKTPNIDMKTQEFNIEGPERKYKVSNVKVPSISGTSVQNVNITGPAGTAGDFSISAPKTEGDIKAPSIEIKGPKLMGSNVDLNLPKAEIENKQTGVEIRLPSKPDIEGADGKITYPEFKKTSITGPNISMPEVNLNIKGQKLKGSVETSVPKVEGHIKEPEVAVERQDGPERGFGMPIFGLKGQKVEGPGFDVKISKADVELKESNLNIKASKLDTERSDGTIKDNKIVMPSVSGPTIYMPGADFNLTGSKLKGDVDASLPKIEGDIKAYDMDYKAPKHNIDRP--EGKLKSPEFNMPS--VSGPNISMPDVDLNLNGSKLKADVDVDVSVSKVKGDIKVPDVDIKPPKVDIKVPEVEIKGPKFNMPSISDSNNSMPNVDFNLKGQKMKSDVDVSVLKVKGDLKDPGVNIKAPNFEIEGSDGKIK--DSKLSMSSISGPNISMPDVDFNLKESKLKGDVDVSVPKVEGDIKAPKIEHEGP--DLEGG---FKMPKINIPKFGSKGPKMEGPDMDVKFPKTDIDIKAPDVDVKAAQLDIEGPEGKVKGSKFKMPFS---GPTISMPDVDFNLKGRKMKGDVDVSIPKVEGDVKVPGVEIKGPRVDIEGPEGKIKGSKFSMPSISVPNVSMPDVDFNLKGSKLKGDVNVSVPKMEGDVKAPKVELEGPDIEGPEGGFKMPNIKMPKFGSKGPKVEKPDIDVKIPKTDIDIKAPDVDIKAPELDIEGPEGKVKGSKFKMPFS---GPTISMPDVDFNLKGPKLKGDVDVSVPKVEADIKAPKVELEGP--EIEGPEGGFKMPKIKMPQIGFKGPKVEGPDVDVKIPKTNIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIP---FSGPNISMPDVDFNLKGPKLKG--DVSVPKVKGDIKAPKVELEGP--EIEG-------PEGGFKMPTIKMPKFGFKGPKVEGPGMDVKIPKTDIDIKGPDVDIKAPELDIEAPEGNIKDPKLKMPSLSR--PTISMPDVDFNLKGQKLKGDVDVSVPKMQGEIKAPKVELEGQ---------DIAGPEGGFKMPKIKLPQFGFKGPKVEGPDVDVKIPKTEIDIKAPDVDIKGPEIDIEAPEGKVKGSKFKIP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKAPKGDLEGP---------EIEVPEGGFKMPTIKMPKFGSKGPKVEKPDIDVKIPKTDIDIKAPDVDIKAPVLDIEGPEGKVKGSKFKMP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVKGDIKAPKVELEGP---------EIEGPEGGFKMPTIKMPKFGFKGPNVEGPGLDVKIPKTDIDIKGPDVDIKAPKLD--------------------------------------------------------------------------IEAPEGNIKDPKLIIPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKAPKVELEGS---------DIAGPEGGFKMPKIKMPQIGFKGPKVEGPDVDVKIPKTDIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKAPKVELEGPEIDGPEGGFKMPTIKMPKFG-----------------------------------------------------------------------------------------FKGPKVEGPDVDVKIPKTDIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKAPKVEIEGP---------EIEGPEGGFKMPTIKMPKFGFKGPKVEGPGMEVKIPKTDIDIKGPDVDIKAPELDIEAPEGNIKDPKLKMPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKASKVELEGPDIAGPEGGFKMPKIKMPQIGFKGPKVEGPDVDVKIPKTDIDIKAPDVDIKGPEIDIGGPEGKVKGSKFKIPFSGPNISMPDVDFNLKGPKLKGDVDVSVPKVEGNIKTPKVELEGPEIE---------GPEGGFKMPTIKMPKFGFKGPKVEGPGMDVKIPKTDIDIKGPDVDIKALELDIEAPEGNIKDPKLKMPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKAP---------KVELEGSDIAGPEGGFKMPKIKMPQIGFKGPKVEGP-------------DVDVKIPKTDIDIKAPDLDIKSP-------EIDIEGPEGKVKGSKFKIP---FSGPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDITAPKVELEGPEIE---------GPEGGLKMPTIKMPKFGFKGPKVEGPGMDVKSPKTDIDIKGPDVDIKAPELDIEAPKGNIKDPKLKMPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKAPKVELEGS---------DIAGPEGGFKMPKIKMPQIGFKGPKVEGP-------------DVDVKIPKTDIDIKAPDLDIKSPEIDIEGPEGKVKGSKFKIPFS---GPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDITAPKVQLEGP---------EIEGPEGGFKMPTIKMPKFGFKGPKVEGPGIDVKSPKTDIDIKGCDVDIKAPELDIEAPEGNIKDPKLKMPSLTR--PTISMPDVDFNLKGPKLKGDVNVSVPKVEGDIKAPKLELEGP---------EIEGPESGFKMPKFKMPHIGFKGPKLESPDLDVKIPKADFEVKSPDLDLKTPELDIEGPEGKVKGSKFKMPFS---GPKISMPDVDFNLKGPKLKGEVDVSVPKVKGDIKATEVDIKTPQIDIEGPEGKPKGSKFSIPSISGPNISMPDADFSLKGPKLKGDVDVSVPKVEGDIKAPNVEIEGPDIKGPEGGFKMPKIKMPRFGFKGPKVEGPDVEVPKTDIDIKAPDVDIKSPELDFEGPEGKVKGSKFKMP---FSGPTISMPDVDFNLKSPKLKG--DVSVPKVEGDIKAPKVELEGP---------EIEGPEGGFKMPNIKMPKFGFKGPKVEGPDVDIKIPKTDIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIPFS---GPTISMPDVDFNLKGPKLKGDVDVSVPKVKGEIKAPDVVVKTPKVDIEG-------------------------------------------------------------PEGKLKGPKFNIP--SISGPNISMPDVDFNLKGPKLKG--DVSVPKVEGDIKAPKVELEGPEIEGPES---------GFKMPKFKMPHIGFKGPKVEGPDVDVKIPKTEIDIKEPDLDIKGPELDIEGPEGKVKGPKWKMPSFSR--PTVSVPDVDFNLKGPKLKGDVDVSLPKVEGGVKAPKVELEGP---------DIEGPEGGFKMPKFRLPKFGFKGPKVERPDMDMKIPKADFEVKSPDLDIKSPEIDIEGPEGKVKGPKLKMPSF--PVPKISMPDVDFNLKGPKLKGDFDVSVPKVEGDFKAPDVDVKTPKVDMEGPEGKFKGPKFQMPSFSGPNISMPDVDFNIKGPKLKGDVDVSVPKVQGDIKAPKIELEGPDIEGPEGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKSDFEVKSPDLDIKSPEIDIEGPEGKVKGPKFKIPSF--TGPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKLPGLDVEAPKVDMEGSEGKLKGPKFSMPSISGPNFSLPNVDFNLKGPKLKGDVDVSIPKVEGGVKAPKVEIEGPDIESSEGGFKMPNIKMPKFGFKGPKVEVPDMDVKIPKADFEVKSPDLDIKSPEIDMEGPEGKVKGPTLKMPSFS--GPKISMPDVDFNLKGPKLKSDVDVSVPKVEGGIKAPKVEIEGP---------DIEGREGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKSDFEIKSPDLDIKSPEIDIEGPEGKVKGPKFKIPSF--SGPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKLPGLDVKAP-----KVDMEGSEGKFKGPKFSMPSISGPNFSLPNVDFNLKGPKLKGDVDVSVPKVEGGVKAPKVELEGPDIESPEGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKADFEVKSPDLDIKSPEIDIEGPEGKVKGPTLKMPSF--SGPKISMPDVDFNLKGPKLKSDVDVSVPKVEGGIKAPKVEIEGP---------DIEGREGGFKMPNIKMPKFGFKGPKVEGPDMEVKIPKADFEVKSPDFDIKSPEIDIEGPEGKVKGPKFQMPSVSR--PKMSMPDVDFNLKGPKLKGDVDVSVPKVEGGIKAPKVEIEGP---------DIEGREGGFKMPNIKMPKFGFKGSKVEGPEMDVKIPEADFEVKSPDLDIKSPEIDIEGPEGKVKGPKFQMP--SVSLPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKLPSLDVEAPKIDFEGSEGKLKGPKFSMPSISGPNFSLPNVDFNLKGPKLKGDVDVSVPKVEGGVKAPKVELEGPDIESPEGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKADFEVKSPDLDIKSPEIDIEGPDGKVKGPTLKMPSL--SGPKISMPDVDFNLKGPKVKGDVDVSVPKVEG-------DIKVPGLDIKAPKVDIEGPEGKLKGPKINIP--SISGPNISLPTVDFNLKGPKLRGDVDVSVPKVKGDVKAPDLDIKTPEIDIEGAEGKIKGPKFRIPSVSM--PKISMPEVDFNLKGPKLKGDVDFSVPKVEGDVKAPDVHIKGPEVDVET-------PEGKITGSKFKGP--SFSGPNISLPDVDFNLKGPKLKGGVDVSVPKVQGDIKATDFNINLPNIDGDIPEGKVKGPKLKMPSLSGPEGSIEVNLPETNVKKPKFKMPKFKFPSFGHKGPKVEGPDVDVKIPKADIKFKSPDLDNESPELNIEGPKGKIKASKFSMP--TISGPKVSMPDVDLNLKRP------------------------------------------------------------------------KLKGDVDVSVPKVEGNISVPDVDLKSPEVEFEGPEGKIKGPKGKIPLLSGPNISMPHVDFNLKGPKLKSDVDVSVLKVEGDIKTPKIEHEGPDIEGPEGGFKMPKLKIPQFGFKGPKVEGPDMDVKIPKTDIDINAPDVDIKAPELDIDGPEGKIKGPKLTKPSL--SGPTISMPDVDFNLKGRKMKGDVDVS---VPKLQGDIKVPGMDIKGPQVDIEGPEGKIKGSKFSMP--SISGPKISMPNVDFNLK-------GPKLKG-DVDVTVPKVEGDMKAPKVELEGPDIEGPEGGFKMPKVKMPKIGFKGPKVEGPDVNVQIPKTDIDINAPDVDIKSPELEIEGPEGKVKGHKLKMPFSGPTISMPDVDFNLKGLKLKGDVDASAPKVKGDIKIPNVDIKGPEVDIEGPGRKFKGPKFQMPSVSGPNISMPDVDFTMPDVDVNLKGPKLKGDVDVSVPKVEGHIKAPKVDIEGPDFDVDGPEVGFKMP--KLPSLGLKGPNVEGPEIGVKIPKTNIDVKAPGVDIESPDLNIEGPDGKIKSPKFKIPTVSIPKVPMPDVDFNLKGPKLKGDVDVSVPKMEGDINGAKVKFEGPGYEGPEGGFKIPKMPSFGLKGPNVEGPDVDIKLPKAGVDVKGPEIEVKSPDLEIKGHEGKIKGPNFKMPSLSGPQISMPDINIKGPKVKGDMGISGPKTGGDLKSAKVDIKGPHVDLESPEGGLKMP---TIKMPAFGFKGPKVDGPDIDFNLPKTDVDMKGPEIDIKTADLDTDGLGGGLKNVKFPKFKGPHFGIKTSGGSLSVPEQDVEATIDAKSPDVTLSGPDANIKVPKTKKSKFSLGVRSPKLDADIPDAGGNFEGPDMNVDVKGKKGKFKLPKGKGKSKTFDADLKTEMVELETNEPEIHIKSTKVKKPFFGRLHFPDVEFDIKSPKVKASSSASGTMKSSDVDLPSASLKTDIQTPDASLDSPDLKTKGAKVKMSKYSMSSSKLKTSDLDVRDATLEIPEKTMHSPDVSVAGSGINGKRSAKIDIEGKVQSVESAVPSTNVSGGVIDADLGIAEQKGVKGSIGIAGFNVGGQKEDTASGIGLKSDASLSGGIENQEGNLTFPKVKVPKFGIALPRVEPREMREDIGSGELAGGAKVSSQGLEMQKTDVKSSGGKVKVKMPKL-FVKSKSKGGSAADLTVEGEDADATSKGAAKVSKELSLSSGELTSGKLTVEESSGFKVSPKSKSASLDFFKKSRHHSSSVSEEGALASPVSTEGHLQAEAGNVSLDVGDTKVKGKKGKLKFSTIGGFSSKSKGSYEVTD-ESEAMTESASGVAQPSKKSRMSSSSSSDSGTKGSIRLPQLEISVSPKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B829-1", "uniprot_id": "A0ACD6B829_DANRE", "id": "A0ACD6B829-1", "name": "", "aln": "-----------------------------------------------MALYQRSLSDSLLLEDNVSG------------EYTDLHFLEGEDIVGASDQLELKRNKQKKNEAVDILKLINNDKEFSKHG-------------LKSSRSLENLDMKAPVEVWKDSYDRLYNAKVKRFLKGSQVAKDKRHSKHGSG--------------QETTETLDRKSKVNIATLLQNADRMCLAPSETEFDEKTRSSISHYDP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDSTGDLMRAKLKTN--------------------------------------------------------------------------------------------TARDFSSLQSKVNLTNVEHEINLRGGTYTDLEKDVGFNT--PDRTFSHGQVSPVMHLTKGHFKTPKAVLNSP-----------------------------DMNMDVPSDNVEKSKFKLPKFSFSGNNNPDIKYDASMK-----------------GSPAEVAAGLNG------------------------------------------------------------------PNIKIDGPKVDYKGLKTDLDMDMPSGKPKAALSGPKMMTS--------------------------------------------------EMDVSTSKFNADCNSPDIKIRG-----QKPGMDVDLPKGNIKAS--------------------------------NLNPPNLDLNASDLNVKAP----------------SGPNLKIKSSDLNFKNSNVN-----------EGINDPGMDLTLPHADLKNP-----------NDFGLTGSKIQTPNYDLKTPEMDLSTPKLKTGLDSTDINIKCQKPDITDTNIDLSKGKITVPNLKTPSHDFNAHDLDIN-------------------------------------------------------------------------------------------------APSGKIKMPKLKIFGNKPEGSSLKIKSSDLNLKTPKIKGGIDTPELNLTQPQTDLKAPNMDIKSPDASKLKMPRPHMNVDANIEQHDLDLSALTPKLNAGIKSPHIDINGPIADIKGPKTDLTLPNMDMPLE------------------------------------------KKKMPTFKMPDFGLSAPNIRTLDADLKTP------QMNLSAPKFKGDFNSP------------------------------------------------------DLSISGHKPDITAPDMNGDFSKGKIKG------------------------------------------------------------------------------------------------------TNLKNPNFDMDTPDFKMNSPSSKLKLQKFGISGSKKKGPDLKIKSPNLNIKSPKMKGGIDT--------------------------------------------------------PDMDPTLP--QVNLKAPNLDLKSPDIDLKDPSG-----KFKMPSLGLPGLKEPHINVDAGIDQPDLN--VSPLTPKLNAGINGPDIDIHGP-----------------------------------------------HADFKGLKTDLKLPDMD----------------------------------------------------------------------------MPSGKKKMPNFKMPSFGLTGPKLKTPDYDLKTP------DMDLFPPKFKADFDSPDINLGHN-------------------------------------------------------IDVTAPNLNVDLPKGKIKGP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLKTPDLDMNAPNFDINAPSGKMKLPKFGLSG-KPKGPDFKINSPKLNLKSPKIKGGIDT----PDMDMTLPQADFKSPNLDLKSPDIDLNGPSGKLNMAKPKMPSLNLSGLKGSHMNADVNHPDLNLTASTPKLNAGISGPDIDIHGAGLKGP----------QTDLTLPDMDMPPGKMKLP----------------------------------------------------------------NLKFPKFGLSGPKLKTP------------------DYDLKTPDMDLSPPKFKADFDSPDINLG------------------------------------------------------------------HNIDVTAPNLNVDLPKGKIKGPDLKTPDLDMNAPDFDINAPSGKMKLPKFG---------LSGKPKGP--------------DLKINSPKLNLKSPKIKG---GIDAP--------------------DMDVTLPQTDFKSPNLDLKSP-------DIDLNGPSGKFNMAKPKMPSLNMSGLKG--PHMNADVDHPDLN--LTASTPKLNAGMSSPDIDIHGPG--------------------------------------------------------------------------------------------------------------------LKGPKTDLTVP---------DMDMPSGKMKLPNLKFPKFSLSGPKLKTP-------------DYDLKTPEMDLSTPKFKADFDSPDINLG-------------------------------------------------------------------------------------------------------------------HNIDVTAPNMNVDLPKGKIKGPDLKTPDLDMNAPSGKLKLPKFGFFG-------------------------------------KPKGPDFKINSPKLNLKSPKIKG-GIDTPDMDLTLRQADFKS--PNLDLKSPDIDLNGPSGKLNMAKPKMPSLN-----------MSGLKGPHMNADVDHPDLNLTASTPKLSAGISSPDIDIHG--------------------------------------------------------------------------------------------------------------------------------------AGLKGPQTDFTLP--------------------------------------DMDMPSGKMKLPNLKFPKFGLSGPKLKTPDYDLKTPDMDLSPPKFKADFDSPDINLGHN--------------------------------------IDVTAPNMNVDLP-----------------------------------------------------------------------------KGKIKGP-----------------------------------------DLKTPDLDMNAPDFDINAP------------SGKMKLPKFGFFG----------KPKSPDLKINSPKLNLKSP---------KIKGG-------------IDTPDMDLTLR---------------KADFKSPNLDLKSP-------DIDLNGPSGKLNMAKPKMPSLNLSGLKGPQMNADVDHPDLNLTASTPKLNAG-----------------------------MSSPDIDIHGAG------------------------LKGPKMDFTVPD----------------------------------------------------------IDMPSGKMKLPNLKFPKFGLSGPKLKTPDYDLKTPDMDLSPPRFKADFDSPDINLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------HNIDVTSPNLNVDLPKGKIKGPDLKTPDLDMNAPDFDINASSGKMKLPKFG---------LSGKPKGPDFKINSP--------------KLNLKSPKIKG--------GIDTPDMDVTLPQTDFKS--PNLDLKSPDIDLNGPSGKFNMAKPKMPSLNMSGLKGPHMNADVDHPDLNLT----ASTPKLNAGMSSPDIDIHGPGLKGP----------------------------------------------------------KTDLTVPDMDMPSGKMKLPNLKFPKLGLSGPKLKTPDYDLKTPEMDLSAPKFKADFDSPDLNLDN------NLYVTAPDMNVDLPKGQMKALDLKKPN------------------------------------LDMRMPTGKINMPTLKMPKFGVSGTKIKTPDYDLKTPEMDLSAPEFKADLDTTDINIKGNKPDITGP--------------------------------DMDFDIPKGTFKGP--NLKTPNFNMSAPDLDINAPSGKMKLPKFGKPKG--TNFKMTYPKLTFKNPQNKGGIDIPQTDFKSPNLDADLDHPGLN---------------------------------LSASTPKLNAGINSPDMNVHGFNADHKG---------------------------------------------------MTTDLTPPDINMPSGKMKLPNLKMPKFGLSGPKLKTPEYDLKNP--EIGLSAPKADFDSPEFNIKGQKPEISGP------------------------------------------------------------DMDVNIPKNKFKGPSFKKPNIDMNAP-----------------------------------------DLDINSPSGKLKLPKFSLSGSKPKSPEFKVESQNLNLKTPQIKGGIDT----PDMDLNLLQAKMKTPKLDLKSPDVDLNDPSGKFNMAKPKMP--SLNSPGLKGPHMDADIDHPDLN---LSASSKLNAGVKSPHIDIDGPNADFKVPKTDLTLP-------------------------------------------------------------------------NMDMPSSKKKMPNFKIPDVGFTGPKINMPDYDKPAKIN-------------------------------------------------------------------------------LSAATFKADLDSPDINFRGHKPDITAPD--------------------------------------------------------MNVNVPKSKINVPNFKK----------------------------PNVDLNTPEIDIDAPSAKMKLPKIGLSDLKAEGPDFKMKSPKLKTKSPKINGGIDTPGMDLTLPQTDLKTSNLDFRPPDIDVNGPSGKFNMSKLKMPSLGLSG-------------------------------------LKEPHFDDDIDHPDIRLSSS--------PPKLNAG---INHPDFNIHGPNGDFTLPKTEMPS--------GKIKTSTFKMPDIGFSGQKIKTPDYDLKAPN-----LDLFNSPDLSTRSHKPDF-------------R-------------------------------------------------------------------------------------------------------------------VPDKNVDFPKGKIKATNFKP-------------NLDVYTPELD-----------------NPDFQGLGSNDDFHDYTKMHANNFAIPRGNIKAGKTYDLDPSLRDIRMPNHQKYGTSKFTMQDPYFDLNSG----------------MNISGKAQRPKMTRHLP------DSPDVTMALPTPRPRTSG----------VVPTSSDVYYSEMSGAHRSRDHKRTG------------SNFEIDDSWN---KISVPKLQAPTRTENLPVRNSNMGMSPKQISPHRGG------DARYYRKTQMVPRRHYTTDDICYTYKG--------------------------------------------------------------------------------------------------------MPRRDGRGNEQSDYSRRRTMR-------------------HLQIQAMDLEVPESTLKGSKMNVLKLM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : ...* : :. .* . **::****: :: . : : : : . * * . : . . . :. .:.*.*:*. *:* *:..: .:. .. : *: *:* . : .: .: : . * .: . .. : . : .:. . *: . * : : . ..:. : . * * :. * : * . ::. ..:: ..:: .. . : * .. :* *.* : . ... . * . ::. . :. :.. .: . :** ...:.. : ::.:: . * :: . *: *: .:. * ::::*.:.:::. . *::.: . *::.* .::: :: . :: * *:.. .*. * * : *: *:: *: *:. . : :.::.*: : .:.. ::.:. *.:. *. *:: :. .:: .:****: * * * ..:.:: .. ::. . .:..*::: : .:*..::.: .:. *.::.. : : . : . **::..:*.*::::. * ::.**. .:.:*::.** * * ..**:* : .*:: *.*:. ::*.**.:*::: * : :.* . ** :.::. : .:*::*. ::. *..*:. *:..::.*..*:* ** :. ..* :.: ::::*.**:**.:*. *::* .:* ::::..*.:* . * :.::.*.. ***** : . . ::. :. *. : . *:::. :: *.:::.** . ...* ..*:. *.:: *. : * *:: :*.: .:. ** .:: : *: **. .::. * ::: :* *::::: *:**:**. ::. *.:.:. :.::: *..*:* .** :. . * :.: . .::**.**:**.:*. : ::. *..:::.* ::.**. ::*.. ***.:.: * * . :*. *. :: . *.:: . .:: . :*.. . :::**:*: *: ::: *. :.**::. . .: ::.*. **.*.*.* . :: .:*: . ::.:: *..::*.*.:* *.: * :.: . ::* **. :.*. *.* : *. * **:* :..* *: :. : ::*.* :*:. * :: :: *..* : .* *:* :.. : *.:: .:. *.:: : . .*:::. : *.::: ** :*.*: :: . : *. * *:.*:*.: : * . * : *:. *: : . . *:. *:::: .:*: *::::: *..: *.*.:* *.: *. .: .:.: * . .**: :: **::: : * : *::*:.: :**.. *.:*:. *:::::**..*:: .* *** ***:::.:** . :: .. . .* *.:*:. . :. *: *:.* ::. * ...*:**:.: * * : *: *:: . *:. ..*.. *:::: :*.: .::: :: ...:*** *:* * ::::.*..: . :.*:*::.: * . ..::.:. *.:::. * *:** :. **::: *: :...:.*:::::.* *:.**. ::*.* ::*.:.. * * : :. *. :: . *.:: :* *::*:: * :* **:*: *: :. *. :*:*::*:***.: * * : *: *:. *. ::. . *.. *:::: .:*: *::::: ...*.*** :* *.: .*.:.: . ::* **. :.* * *...*:.* . :* *::* : *::**.:*::*:. *.:*:. *:::::**..*.: .* *:*.: .. * . *.. . ::. * **::. :. * :*::.* . :: ** . :*:*::*:**:.: * * : *: *:. *: *:.. . *.. *:::::. . .. *.: . ** .* *:: . *:. ::**.:*****.. * * : *: ::. *: *:.. . *:. .:::*.* . .:.** *:.. :* :* * ::: * *:.. . :*:*:. ** . * *.: .. *: . :. *. *:. *::: : . :: :..* **::. :: *.:::.. : * . :: ** . :*:*::*****.: * * : *: *:. * :: :..*. *:. *:..: * . ::.** .:::: *:.*:***.:: * :..* ::**: ..**:* *** :.. *::.: . ::*:* *::**.:* : *:: ...:* *::.:.: *.**:. .* * * :..* :. *.:* ::. *.:: : .*::..:*....:* *: * . *. .: * *:: *..* * .:*.:* :..**:.*** * * :: ...:.::. *: :::. : :. *: ::. *. :::*:.* *.**:. *:::::.*. *:* **: ..: ..* :.: . .:. *. *::* .* . :. : :* . :*:: * :*.:**..*:. ..:.** :. . . .:: ***. **:. : *. ::: *. *. : .:: * . . : .: :** .:. . .:. . .:. : *:. ** *:: ..*:*:..* :..: *::. . .::* : :. : .: . . . *. . : . . ::. .: . :*:.* : .: * .:. : : . . : *. . : :. .:.. : . :..*::: * . . . : . : . . . * . . . . : . * :: :. *: .: .:.* ", "identical_positions": 572, "similar_positions": 1392, "identity": "8.08%" }, { "cls_id": "homologset.agr.HGNC:3471", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5QJV7-1", "uniprot_id": "ERR1_RAT", "id": "Q5QJV7-1", "name": "Steroid hormone receptor ERR1", "aln": "MSSQVVG----IEPLYIKAEPASPD----------SPKGSSETETEPPVTLASGPAPARCLP--------GHKEEEDGEGAGSGEQGSG----KLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKT-APVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08580-1", "uniprot_id": "ERR1_MOUSE", "id": "O08580-1", "name": "Steroid hormone receptor ERR1", "aln": "MSSQVVG----IEPLYIKAEPASPD----------SPKGSSETETEPPVTLASGPAPARCLP--------GHKEEEDGEGAGSGEQGSG----KLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKT-APVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11474-1", "uniprot_id": "ERR1_HUMAN", "id": "P11474-1", "name": "Steroid hormone receptor ERR1", "aln": "MSSQVVG----IEPLYIKAEPASPD----------SPKGSSETETEPPVALAPGPAPTRCLP--------GHKEEEDGEGAGPGEQGGG----KLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8J1-1", "uniprot_id": "A0A8M2B8J1_DANRE", "id": "A0A8M2B8J1-1", "name": "", "aln": "MSKGIMSSRERRSDLYIKAEPSSPEGGGGGGGGRTSPGGASSDSSQSGGGGSRGEGAGRYSPPLYTPALRCHFKEEGADGAEEGSTGSGGGRCKYALSTLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGNIEYSCPASNECEITKRRRKACQACRFTKCLKVGMLKEGVRLDRVRGGRQKYKRRPEVENATYQS--APIPLRKEGEKGSS----SIIVSHLLVAEPEKLFAMPDPLQPDTAQRTLTTLCDLADRELVVIIGWAKHIPGFLSLSLADQMSVLQSVWLEVLVLGVAYRSLGCEDEVVFAEDFVLDEEMSRVAGLTELNAAISQLARRFRALQLDREEFVMLKAIALTNSDSVYIEDMEAVQKLRDLLHQALLELEVQRR-PD---DPQRAGRLLLTLPLLRQTAGRALTTFYSIKTRGGVPMHKLFLEMLEAMMDSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. ::. . *******:**: ** *:*. .::. : * .. * * * :**..:** *. *.* * .**:************************************.******************************:**************************: .: . .. ** * .: . :******.*****:***** ** :::***** ***:** *.*** **** ****:**********:******** *** :**:.****:***** :*.*** :*.**: **.**::**:*:***:*:***:**:*****:*** ***::**: **:**** *. * *. : :*****************:.*: **.:* .* **************** ", "identical_positions": 279, "similar_positions": 78, "identity": "61.86%" }, { "cls_id": "homologset.agr.HGNC:3473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11475-1", "uniprot_id": "ERR2_RAT", "id": "P11475-1", "name": "Steroid hormone receptor ERR2", "aln": "---------------------MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGMALGTHANGLDSPPMFAG---AGLGGNPCRKSYEDCTSGIMED-SAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPDDVPEGDIKALTTLCDLADRELVFLISWAKHIPGFSNLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLELYRAILQLVRRYKKLKVEKEEFVMLKALALANSDSMYIENLEAVQKLQDLLHEALQDYELSQRHEEPRRAGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61539-1", "uniprot_id": "ERR2_MOUSE", "id": "Q61539-1", "name": "Steroid hormone receptor ERR2", "aln": "---------------------MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGIALSTHANGLDSPPMFAG---AGLGGNPCRKSYEDCTSGIMED-SAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYNCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLNLPISPPAKKPLTKIVSNLLGVEQDKLYAMPPNDIPEGDIKALTTLCELADRELVFLINWAKHIPGFPSLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLDLYRAILQLVRRYKKLKVEKEEFMILKALALANSDSMYIENLEAVQKLQDLLHEALQDYELSQRHEEPRRAGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95718-3", "uniprot_id": "ERR2_HUMAN", "id": "O95718-3", "name": "Steroid hormone receptor ERR2", "aln": "---------------------MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAG---AGLGGTPCRKSYEDCASGIMED-SAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HMR2-1", "uniprot_id": "A0AC58HMR2_DANRE", "id": "A0AC58HMR2-1", "name": "", "aln": "MDISELCIPDPLSYHNQLLNRMAAEERHMTSSCGSYIKTEPSSPSSLVDSASHPSPGAHSDASGGYASAINSHSTGLDSPPMFTAGGALGPGASSCRKRFEDCSSTLLDDPAAIKCEYMLNSIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRMDAENTAYLGLTLPPPAKKPLTKIVSHLLVAEPEKIYAMPDPTMPESDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILSIVFRSLPYEDELVYAEDYVMDEEHSRLTGLLDLYLSILQLVRKYKKLKVEKEEFVTLKAIALANSDSMHIEDVESVQKLQDALHEALQDYESCQHAEDPRRAGKLLMTLPLLRQTATKAIQHFYSIKMQGKVPMHKLFLEMLEAKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::::**: *****:********** :*: ** **.. ******:. *:.:*:.********:. * *...*** :***:* :::* :*********:****************************************.**************************************************:*:*.:.**.* :.************ ** .* :*:**** :**.*********:*******.:*.********..*:******************.**:*****:*:*.*****:********.***:** :******:***********: ***:********:**::*:****** ********* .*: *:* *:****:*********:**:*****:*:******************", "identical_positions": 335, "similar_positions": 75, "identity": "73.14%" }, { "cls_id": "homologset.agr.HGNC:3474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62510-1", "uniprot_id": "ERR3_RAT", "id": "P62510-1", "name": "Estrogen-related receptor gamma", "aln": "MDSVELCLPESFSLH-------------------------------------------YEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPY-------NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62509-1", "uniprot_id": "ERR3_MOUSE", "id": "P62509-1", "name": "Estrogen-related receptor gamma", "aln": "MDSVELCLPESFSLH-------------------------------------------YEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPY-------NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62508-1", "uniprot_id": "ERR3_HUMAN", "id": "P62508-1", "name": "Estrogen-related receptor gamma", "aln": "MDSVELCLPESFSLH-------------------------------------------YEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPY-------NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B590-1", "uniprot_id": "A0A8M2B590_DANRE", "id": "A0A8M2B590-1", "name": "", "aln": "MDSVELSLPECFSLHSDQQMNLSKAQVNSEDKYAKCGAWRTQQQYDIEASHMRDAHALYNQRLLCRMSNKDRHIESSCPSYIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPTLYGPTGALGPSGTGAKRYEDCSSTITEDSQIKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLTVGMMREGVRLDRVRGGRQKYKRRIDAENSPYLNPQLALPPKKPFPFGCLADNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVNIGWAKHIPGFSTLSLADQMSLLQSAWMEILILRVVYRSLSFEDKLVYAEDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHVEDPRRAGKLLMTLPLLRQTSTKAVQHFYSIKQDGKVPMHKLFLELLEAKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.***.**** *::.************:***.*:********************************************.** .: ** **. * *:******.**.* ***************************************************************************.***::*******************************. *.***: ******************************************** ******************************** **********:****:*******************************************************************************:********:*******************.** :***********:*****", "identical_positions": 418, "similar_positions": 28, "identity": "82.28%" }, { "cls_id": "homologset.agr.HGNC:3477", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62495-1", "uniprot_id": "ERF1_HUMAN", "id": "P62495-1", "name": "Eukaryotic peptide chain release factor subunit 1", "aln": "MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQG-TEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLD---DY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BWY3-1", "uniprot_id": "ERF1_MOUSE", "id": "Q8BWY3-1", "name": "Eukaryotic peptide chain release factor subunit 1", "aln": "MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQG-TEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLD---DY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2Q7-1", "uniprot_id": "ERF1_RAT", "id": "Q5U2Q7-1", "name": "Eukaryotic peptide chain release factor subunit 1", "aln": "MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQG-TEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLD---DY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPH7-1", "uniprot_id": "ERF1_DROME", "id": "Q9VPH7-1", "name": "Eukaryotic peptide chain release factor subunit 1", "aln": "MSGEETSADRNVEIWKIKKLIKSLEMARGNGTSMISLIIPPKDQISRVSKMLADEFGTASNIKSRVNRLSVLGAITSVQHRLKLYTKVPPNGLVIYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVATQLFITNDKPNIAGLILAGSADFKTELSQSDMFDPRLQSKVIKLVDVSYGGENGFNQAIELAAESLQNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLRALELGSVETLICWENLDIQRYVLKNHANSTSTTVLHLTPEQEKDKSHFTDKESGVEMELIESQPLLEWLANNYKMFGATLEIITDKSQEGSQFVRGFGGIGGILRYKVDFQSMQLDELDNDGFDLD---DY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12385-1", "uniprot_id": "ERF1_YEAST", "id": "P12385-1", "name": "Eukaryotic peptide chain release factor subunit 1", "aln": "MDN---EVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFKDAE---DNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES-EDEYYDEDEGSDYDFI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .::*:****:***::*** ***********:****.**. ***:**:****************.****.*::****..:* ****:*** *:**:******.:*:**:*****************.*: ** *.******:**.*:***::.**** *************************** ************.*.* **:.** *: **:*********:*::*::** ** .**:.:**:**************::* * ***::*****: ***********:*:*::***:**::*:** ** :***: **.:: . :: :: : ****. ** :* * :::.. **:**:* *** ******::****.**:*** ******.:***:*:*: : : ::: :* * ** ", "identical_positions": 281, "similar_positions": 100, "identity": "63.29%" }, { "cls_id": "homologset.agr.HGNC:348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41738-1", "uniprot_id": "AHR_RAT", "id": "P41738-1", "name": "Aryl hydrocarbon receptor", "aln": "-MSSGANITYASRKRRKPVQKTVKPVPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRSRGQDQCRAQ-VRDWQD------LQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDETHGLPQPAVYYTPDQLPPENTAFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCNKGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLLAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSMTLPFMFATG-----------EAVLYEISSPFSPIMDPLPIRTKSNTSRK-----------------------------------------------DWAPQSTPSKDSFHPNSLMSALIQQDESIYLCPPSSP---APLDSHFLMDS---------------------------------------------------MSECGSWQGSFAVASNEALLKHEEIRHTQDVNLTLSGGPSELFPDNKNND-----------------------------LYSIMRNLGIDFEDIR---------SMQNEEFFRTDS--SGEVDFKDIDITDEILTYVQDSLNNSTLLNSACQQQ-PVSQHLSCMLQERLQLEQQQQLQQQHPTQTLEPQRQLCQVEVPQHELGQKTKHMQVNGMFASWNPAPPVSFSCPQQERKHYSLFSGLQGTAQEFPYKSEVDSMPYTQNFAPCNQSLLPEHSKGTQLDFPGRDFERSLHPNASNLEDFVSCLQVPENQRHG-INSQSAMVSPQAYYAGAMSMYQCQAGPQHTPVDQMQYSPEIPGSQAFLSKFQSPSILNEAYSADLSS-IGH-LQTAAHLP---RLAEAQPLPDITPSGFL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30561-1", "uniprot_id": "AHR_MOUSE", "id": "P30561-1", "name": "Aryl hydrocarbon receptor", "aln": "-MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQ-IRDWQD------LQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP----DSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLFAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSTSLPFMFATG-----------EAVLYEISSPFSPIMDPLPIRTKSNTSRK-----------------------------------------------DWAPQSTPSKDSFHPSSLMSALIQQDESIYLCPPSSP---APLDSHFLMGS---------------------------------------------------VSKCGSWQDSFAAAGSEAALKHEQIGHAQDVNLALSGGPSELFPDNKNND-----------------------------LYNIMRNLGIDFEDIR---------SMQNEEFFRTDSTAAGEVDFKDIDITDEILTYVQDSLNNSTLMNSACQQQ-PVTQHLSCMLQERLQLEQQQQLQQP-PPQALEPQQQLCQMVCPQQDLG--PKHTQINGTFASWNPTPPVSFNCPQQELKHYQLFSSLQGTAQEFPYKPEVDSVPYTQNFAPCNQPLLPEHSKSVQLDFPGRDFEPSLHPTTSNLD-FVSCLQVPENQSHG-INSQSTMVSPQAYYAGAMSMYQCQPGPQRTPVDQTQYSSEIPGSQAFLSKVQSRGIFNETYSSDLSS-IGHAAQTTGHLH---HLAEARPLPDITPGGFL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35869-1", "uniprot_id": "AHR_HUMAN", "id": "P35869-1", "name": "Aryl hydrocarbon receptor", "aln": "MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLN------LQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTG-----------EAVLYEATNPFPAIMDPLPLRTKNGTSGK-----------------------------------------------DSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAPFENNFFNES---------------------------------------------------MNECRNWQDNTAPMGNDTILKHEQIDQPQDVN-SFAGGHPGLFQDSKNSD-----------------------------LYSIMKNLGIDFEDIR---------HMQNEKFFRNDF--SGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQQQQSLALNSSCMVQEHLHLEQQQQHHQK--QVVVEPQQQLCQK----------MKHMQVNGMFENWNSNQFVPFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYPMGSFEPSPYPTTSSLEDFVTCLQLPENQKHG-LNPQSAIITPQTCYAGAVSMYQCQPEPQHTHVGQMQYNPVLPGQQAFLNKFQN-GVLNETYPAELNN-INN-TQTTTHLQPLHHPSEARPFPDLTSSGFL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9V8-1", "uniprot_id": "A0AB13A9V8_DANRE", "id": "A0AB13A9V8-1", "name": "", "aln": "-MSSSN--IYASRKRRKPVQKSVK-QPLTCVKSNPSKRHRDRMNEVLASLAREIPFPQEIVSTLDKLTILRLSVSYLRAKSHFKITLNSKSSSQ-------QANNTKQAQE------QPEGEFLLQAINGFLLVVTSSGIVFYVSSNIEDYLGFHQSDVIHQSVYELIHTEDRHEFQRQLHWALNPGFTPDSRQLVQASP--DASRTCYSPEQLSLENSTCLERNFICRLRCLLDSTSGFLAVNFQGRLKFLYGQNESTGDGKRIPPQLALFALACPLQPPSILEIRTKNLMFKTKYKLDFTPIACDTNWNFVLGYTEAELCNSGSGYQFIHAADMMYCAEGHMRMMRTGKTGLTVFRLLTKQNRWVWVQSNGKLVYKNGQPDCIITSHRVITAEEGEENLRNRAMMLPFNFTTG-----------DAVLCAMNCP-----------TSSDPASS-----------------------------------------------DGNTQPKTTR-TVNPDSLLVSLLKQPKSIYLSPADER--------SVLVQS---------------------------------------------------LGNK-DLDGIYSINSQESVSVSRSCPFKQESVFSSER--------DDSCE-----------------------------ILNFMGSLGISLEDLK---------FLQHEDLFINMD---LDSHNDMADLSDDILSHVQQSLKT--------KMDCTVSKNTQGNMKEQELIRNPAQTIIP--NDSCDTITLLSQEQQMTFITDKTEPKIQLT-QIQPYTPQKGITYLQIDPHEHQDTRPQSYNGTGITLPKSSHSTIQTISQHLQFSNLPPFHEQ-VCEALRSP--QVCGNMAEVIDSDIQQVSPLFPPELQPSGCFYLERPILDPKLCTSSSQQLSSSQ----TTEGEPVEFT--TQDLEDLINDMNGVGERNNYSGLDRGMDIRSSLDQQAYIG----TGSPQRNEPPTYAAYV------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIM6-1", "uniprot_id": "E1JIM6_DROME", "id": "E1JIM6-1", "name": "", "aln": "--MSQLGTVYATKRRRRNGKSLKPPPKDGVTKSNPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVLPHIHAHDGYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDIVHQSVYELVHSEDREELQRQLLWNSFLPADMSSMQ---------------LAETLAPDKALYLERSFTVRFRCLLDNTSGFLRLDIRGRIKVLHGQNRKTEE-----PPLALFAYCTPFGPPSLLEIPHKENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMG-GYDLVHYDDLAYVASAHQELLKTGASGMIAYRYQKKDGEWQWLQTSSRLVYKNSKPDFVICTHRQLMDEEGHDLLGKRTMDFKVSYLDTGLASTYFSEADQLVVPPSTSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCRSKRKLQQQNQPQTQQTSPLGGQVGSPAPAVAVEYLPDPAAAVAAAYSNLNPMYTTSPYASAADNLYMGSSMPANAFYPVSENLFHQYRLQGAVGGYYTDYPHSGAPASAYVANGFLSYDGYAIASKADEKWQETGKYYSGYSSGYGSPTSTPQQIPLKTPKSSPQVMEVISCSSDGPSPVGGATPNGVGSVTPKVELAGTTAAAAAGQDPYERQTVLMWGTTHSSGVPLNSHGGRTGAGNPASPQRSTPLGNGLGYASANNNNNDLEPATAAKWNGTKELPGKSGSASTPESYQMQHDDSGLYSASSHTTSPQQQQQQQLQQSQRGVGSNVSAPSSSLTSTGTDQQAVHPSSCHQQQQQQQQQHHHAHPHPHSHHHHHHHHHHETAHQHSSEIILTTHHQQQSQQQQQSLAGYPLHHQLVGVGSGSPPPQPPVALSRSPTTLPAVSSLLNGSASAGGASDIPYQQLAIVSAPLVICAEEVGGGVSSIGRKSSKQQQSLQHLQQQQSLQQQQHAIYQQQHHHSQHHPHHQLLYPANITAHTALAYAPPTAGGAYADGSPLLSFSEVTNTLLNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **:::**: :. *********:*:* * ** :** *:::..**:*::*********:**.*.:.::. .. : :*:::***:***::::* .. **:.: .*:.****:***::*******:*:*** *:**** * .* * .: :. ::: :** * *:*****.:**** ::::*::* *:**:.. : * ***** . *: ***:*** *: :*::*:****: :. * . . :***::.** . * **:::* *: : *..* .:::** :*: .:* *...* *:*:..:*:*:*.:** :* ::* : *** : * :* : . : : *: . * * . . * . : ..:* . . ..:*: .. .: . . . : . . .. : . : . . *: ::. *.. : . . . . . . : . . . . * . : . . . : : ... . *: : : * . . . : . : : .: : .: . : . . : : .. . : : . : : ..: ", "identical_positions": 156, "similar_positions": 222, "identity": "15.03%" }, { "cls_id": "homologset.agr.HGNC:3481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13803-1", "uniprot_id": "ETFA_RAT", "id": "P13803-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAAGRLGGEVSCLVAGTKCDKVVQDLCK---VAGVAKVLVAQHDAYKGLLPEELTPLILETQKQFSYTHICAGASAFGKNLLPRVAAKLNVAPVSDIIEIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAAA-SGGSASSEKAPS-SSSAGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC5-1", "uniprot_id": "ETFA_MOUSE", "id": "Q99LC5-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAAGRLGGEVSCLVAGTKCDKVVQDLCK---VAGVAKVLVAQHDAYKGLLPEELTPLILETQKQFSYTHICAGASAFGKNLLPRVAAKLNVAPVSDIIEIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAAT-SGGSASSEKAPS-SSSVGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13804-1", "uniprot_id": "ETFA_HUMAN", "id": "P13804-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCK---VAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAAT-SGGSASSEKASS-TSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KN94-1", "uniprot_id": "ETFA_DROME", "id": "Q7KN94-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MF---ASNTRNLMRSSILQR-CKSTLVVAEHNNE-VLNPITLNTISAAKKIGGDVTVLVAGTKCGPASEALSK---VDGVTKVLVAENAAFNGFTAESLTPLVLAAQSQFKFTHILAGASAFGKNVLPRVAAKLDVSPISEIIDVKSDDTFVRTIYAGNAILTLKSKDAVKVITVRSTNFPPAAT-SGGSGAVEQAPAGDFASSLSEFVSQELTKSDRPELAGAKVIVSGGRGLKSGDNFK-LLYDLADKFGAAVGASRAAVDAGFVPNDLQIGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADIGIVADLFKAVPELTGKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12480-1", "uniprot_id": "ETFA_YEAST", "id": "Q12480-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFKSLAAVLPRASKAKFLQKNYASTLAFIESSKDGSVSRSSLSLLAAAQKLSNPITAVITGSKAEKTAEALKSSYSCSNLEKLVIFEDSKLDTCLPEQLTPLLVKLLKGGDYSHFVVSNSSVGKSVLPRVGALLDVQPVCEVTVIKDPKTFIRPIYAGNIISTIECQAEKKLLIIRASAFPPIAEGSMDSVTIEKRTDIPPCDLNVTWVKTILTKSERPELTSAQNVVTGGRALKDKETFEKLLSPLADVLHAAIGATRASVDNGLCDNSLQIGQTGKVVAPNLYIAIGVSGAVQHLAGMKDSKVIVAINNDPDAPIFNVADYGLQGDLYKIVPELTEKLGKYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: . :: * : ***.. * :: : :*. ::** ::.. :: :::*:*. . : * . .: *::: :. . .*.****:: . .::*: .. *:.**.:****.* *:* *:.:: :*. .**:*.***** : *::.. *:: :*.: * . * * .* : *: . ::. ****:****:.*: :*:***.**. :.*: ** *** : **:**:**:** *: *.:*:*****:***:****:*:***:**********.*****:**:****:*** *: .**:* ***:* * ", "identical_positions": 130, "similar_positions": 112, "identity": "37.79%" }, { "cls_id": "homologset.agr.HGNC:3482", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FU3-1", "uniprot_id": "ETFB_RAT", "id": "Q68FU3-1", "name": "Electron transfer flavoprotein subunit beta", "aln": "---MAELRALVAVKRVIDFAVKIRVKPDKSGVVTDGVKHSMNPFCEIAVEEAVRLKEKK--LVKEIIAVSCGPPQCQETIRTALAMGADRGIHVEVPGAEAENLGPLQVARVLAKLAEKEKVDLLFLGKQAIDDDCNQTGQMTAGLLDWPQGTFASQVTLEGDK-VKVEREIDGGLETIRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIK-AGDL-GVDLTSKVSVISVEEPPQRLAGVKVETTEDLVAKLKEVGRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCW4-1", "uniprot_id": "ETFB_MOUSE", "id": "Q9DCW4-1", "name": "Electron transfer flavoprotein subunit beta", "aln": "---MAELRALVAVKRVIDFAVKIRVKPDKSGVVTDGVKHSMNPFCEIAVEEAVRLKEKK--LVKEIIAVSCGPSQCQETIRTALAMGADRGIHVEIPGAQAESLGPLQVARVLAKLAEKEKVDLLFLGKQAIDDDCNQTGQMTAGLLDWPQGTFASQVTLEGDK-VKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVVK-AGDL-GVDLTSKVSVISVEEPPQRSAGVKVETTEDLVAKLKEVGRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38117-1", "uniprot_id": "ETFB_HUMAN", "id": "P38117-1", "name": "Electron transfer flavoprotein subunit beta", "aln": "---MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKK--LVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDK-LKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIK-PGDL-GVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHZ6-1", "uniprot_id": "ETFB_DROME", "id": "Q0KHZ6-1", "name": "Electron transfer flavoprotein subunit beta", "aln": "-----MARVLVGVKRVIDYAVKVRVKPDKTGVVTQGVKHSMNPFDEIAVEEAVKLKEKK--LAEEVIAVSVGPAQSQEVIRTALAMGADRGVHVEIPAAEYELLQPIHVSKILAKLALDEKADLVILGKQAIDDDANQTAQMTAAVLDWPQGTFCNKIEKTDAG-LTITREIDGGLETIKTKTPAVLSADLRLNTPRYATLPNIMKAKKKPLKKVT-AKDL-GVDTSPRIEVISVEDPPVRQAGATVADVDALVAKLKEGGHI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42940-1", "uniprot_id": "ETFB_YEAST", "id": "P42940-1", "name": "Electron transfer flavoprotein subunit beta", "aln": "MSAKQQLRILVPVKRVVDFQIKPRVNKTLTGIETSGIKFSINPFDDIAVEEAIRIKEKNKSLVESTHAVSIGSAKAQDILRNCLAKGIDT--CSLIDSVGKENIEPLAIAKILKAVVEKKGSNLVLMGKQAIDDDCNNTGQMLAGLLNWPQATNAAKVEFLDNGRVQVTREIDDGEEVIEASLPMVITTDLRLNTPRYVGLPKLMKAKKKPIEKLDIAKDFPEINIEPQLKIVSMEEPKTKSPGVKLNSVDELIEKLKEVKAI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** ****:*: :* **: :*: *.*:*.*:*** :******:::***: *.:. *** *..:.*: :*..** * * : . * : *: ::::* :. .: :*:::********.*:*.** *..*:***.* . :: . : : ****.* *.:. . * *:::***** ***. **::****** :: : . *: :: .::.::*:*:* : .*..: .: *: **** *", "identical_positions": 96, "similar_positions": 89, "identity": "36.5%" }, { "cls_id": "homologset.agr.HGNC:3483", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921G7-1", "uniprot_id": "ETFD_MOUSE", "id": "Q921G7-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "MLVRLTKLSCPAYHWFHALKIKK-CLPLCAPRCSSTSAVPQITTHYTVHPREKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAIRLKQLAAEQGK-DIRVCLVEKAAQIGAHTLSGACLDPAAFKELFPDWK-EKGAPLN----TPVTEDRFAILTEKHRIPVPILPGLPMNNHG-NYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLYHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTVFAEGCHGHLAKQLYKKFDLRASCDAQTYGIGLKELWIIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVAVGFVVGLDYQNPYLSPFREFQRWKHHPSIQPTLEGGKRIAYGARALNEGGLQSIP-KLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGSLAAESIFKQLTSENLQSKTTG-------------LHVTEYEDNLKQSWVWKELHAVRNIRPSCHGILGVYGGMIYTGIFYWILRGMEPWTLKHKG-SDSDQLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLKDDSIP--VNRNLSIYDGPEQRFCPAGVYEFVPLEQG-DGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UPE1-1", "uniprot_id": "ETFD_RAT", "id": "Q6UPE1-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "MLVRLTKLSCPAYQWFHALKIKK-CLPLCAPRCSSTSAVPQITTHYTIHPREKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAIRLKQLAAEQEK-DIRVCLVEKAAQIGAHTLSGACLDPAAFKELFPDWK-EKGAPLN----TPVTEDRFAILTEKHRIPVPILPGLPMNNHG-NYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLYHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRASCDAQTYGIGLKELWVIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVAVGFVVGLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGLQSIP-KLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGSLAAEAIFKQLTSENLQSKTAG-------------LHVTEYEDNLKQSWVWKELHAVRNIRPSCHGILGVYGGMIYTGIFYWILRGMEPWTLKHKG-SDSEQLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLKDDSIP--VNRNLSIYDGPEQRFCPAGVYEFVPLEQG-DGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16134-1", "uniprot_id": "ETFD_HUMAN", "id": "Q16134-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "MLVPLAKLSCLAYQCFHALKIKKNYLPLCATRWSSTSTVPRITTHYTIYPRDKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAVRLKQLAVAHEK-DIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPDWK-EKGAPLN----TPVTEDRFGILTEKYRIPVPILPGLPMNNHG-NYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLFHDDGSVKGIATNDVGIQKDGAPKATFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVALGLVVGLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGFQSIP-KLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQLTSENLQSKTIG-------------LHVTEYEDNLKNSWVWKELYSVRNIRPSCHGVLGVYGGMIYTGIFYWILRGMEPWTLKHKG-SDFERLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLRDDSIP--VNRNLSIYDGPEQRFCPAGVYEFVPVEQG-DGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7JWF1-1", "uniprot_id": "ETFD_DROME", "id": "Q7JWF1-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "-MSALMKMHR----------VRRLFSPALARSISDVAKYPRITTHYTLNPREKDERWTEVDMERCVEEVDLVIVGGGPAGMSAAIRAKQLAAEKDQ-EIRVCVVEKAAEVGGHILSGAVIDPISLNELIPDWQ-EQGAPLN----TPVTKDTFSFLTGSGRISIPVFKGWPMDNHG-NYVVRLGHLVKWLGDQAEALGVEIYPGCAASEVLFHEDGSVKGIATNDVGIAKSGAPKDTFARGMELHAKTTIFAEGCRGHLTKQIMQKFGLNEGSEPQAYGIGLKEVWEIAPEKHQPGLVEHTIGWPLDRFTYGGSFLYHLNEPTPTIAVGFVVGLNYKNPWLSPFQEFQRFKTHPKVRDVFEGATRIAYGARAINEGGFQSLPQKLSFPGGCLVGCSAGFLNVPRIKGSHYAMKSGMLAAESAFEAINAD--AQSTAG-------------VEPTGYAEKIKDSFVWKDLYSVRNVHPSFHNPLGLYGGLVLSG-FSIFMGGREPWTLKHGP-QDHESLKPASSCPPIVYPKPDGKISFDLLSSVALTGTNHEGDQPAHLTLKDDRIP--VDHNLALYEGPEQRFCPAGVYEYVPNEEG-GNMKLQINAQNCIHCKTCDIKDPKQNINWVVPEGGGGPAYNGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08822-1", "uniprot_id": "ETFD_YEAST", "id": "Q08822-1", "name": "Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "-MIKFTNENLIR-----GIRMTISAKSRHLALGTDMTRKFSLSCRFLNKANLTEEEKELLNEPRARDYVDVCIVGGGPAGLATAIKLKQLDNSSGTGQLRVVVLEKSSVLGGQTVSGAILEPGVWKELFPDEKSDIGIPLPKELATLVTKEHLKFLKGKWAISVPEPS--QMINKGRNYIVSLNQVVGYLGEKAEEVGVEVYPGIAVSDLIYDENNAVKGVITKDAGISKSGKPKETFERGMEFWARQTVLAEGCHGSLTKQALAKYDLRKGRQHQTYGLGIKEVWEVKPENFNKGFAAHTMGYPLTNDVYGGGFQYHFGDG--LVTVGLVVGLDYKNPYVSPYKEFQKMKHHPYYSKVLEGGKCIAYAARALNEGGLQSVP-KLNFPGGVLVGASAGFMNVPKIKGTHTAMKSGLLAAESIFESIKGLPVLEEVEDEDAKMAMFDKEATINLESYESAFKESSIYKELYEVRNIRPSFSGKLGGYGGMIYSGIDSLILKGKVPWTLKFDEKNDGEILEPASKYKPIEYPKPDGVISFDILTSVSRTGTYHDDDEPCHLRVPGQDMVKYAERSFPVWKGVESRFCPAGVYEFVKDEKSPVGTRLQINSQNCIHCKTCDIKAPRQDITWKVPEGGDGPKYTLT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . :. : :: :: .. .::. :: * : .*: ***.****:::*:: *** ::** ::**:: :*.: :*** ::* :**:** : : * ** * **:: : :*. . *.:* * *:* **:* *.::* ::*::** :***:*** *.:::::.::.:***: *:*.** *.* ** ** **:*: *: *::****:* *:** *:.*. . : *:**:*:**:* : :: : * . **:*:** . .***.* **:.: :::*:****:*:**::**::***: * ** .:**.. ***.***:****:**:* **.**** *:*.*.**:***:***:* ***** ****: *: :.. ... . :. * . :*:* ::*:*: ***::** . ** ***:: :* :: * *****. .* : *:**.. ** ****** ****:*:**: :** *: *:*.** : .: : .::.:.::.* *.*********:* *:. . :****:***:******** * *:*.* *****.** *. ", "identical_positions": 247, "similar_positions": 198, "identity": "38.47%" }, { "cls_id": "homologset.agr.HGNC:3488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14921-1", "uniprot_id": "ETS1_HUMAN", "id": "P14921-1", "name": "Protein C-ets-1", "aln": "----------------------------------------------------------------------------------------------MKAAVDLKPTLTIIKTEKVDLELFPSPDMECAD-------------------VPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFC-MNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKP----------------------YQVN--------GVNPAYPESRYTSDYFISYG----------IEHAQ--------------CVPPSEFSE--------------------PSFITESYQTLHPISSEELLSLKYENDYP-------------------------SVILRDPLQTDT---------------LQNDYFAIKQEVVTPDNMCMGRTS-RGKLGGQDS-----------------FESIES--------------------YDSCDRLTQSWSSQSSFNS--LQRVPSYDSFDSE---DYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAG----YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41156-1", "uniprot_id": "ETS1_RAT", "id": "P41156-1", "name": "Protein C-ets-1", "aln": "----------------------------------------------------------------------------------------------MKAAVDLKPTLTIIKTEKVDLELFPSPDMECAD-------------------VPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFC-MNGAALCALGKECFLELAPDFVGDILWEHLEILQKEDVKP----------------------YQVN--------GVNPTYPESRYTSDYFISYG----------IEHAQ--------------CVPPSEFSE--------------------PSFITESYQTLHPISSEELLSLKYENDYP-------------------------SVILRDPLQTDT---------------LQTDYFAIKQEVLTPDNMCMGRAS-RGKLGGQDS-----------------FESIES--------------------YDSCDRLTQSWSSQSSFNS--LQRVPSYDSFDSE---DYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAG----YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27577-1", "uniprot_id": "ETS1_MOUSE", "id": "P27577-1", "name": "Protein C-ets-1", "aln": "----------------------------------------------------------------------------------------------MKAAVDLKPTLTIIKTEKVDLELFPSPDMECAD-------------------VPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFC-MSGAALCALGKECFLELAPDFVGDILWEHLEILQKEDVKP----------------------YQVN--------GANPTYPESCYTSDYFISYG----------IEHAQ--------------CVPPSEFSE--------------------PSFITESYQTLHPISSEELLSLKYENDYP-------------------------SVILQDPLQTDT---------------LQTDYFAIKQEVLTPDNMCLGRAS-RGKLGGQDS-----------------FESVES--------------------YDSCDRLTQSWSSQSSFNS--LQRVPSYDSFDYE---DYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAG----YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDAD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51023-1", "uniprot_id": "PNT_DROME", "id": "P51023-1", "name": "ETS-like protein pointed", "aln": "MELAICKTDLSATKFMLPPALPSSAAIGSSSAVASTASHFLDKAAHELFQLNAINGHLFKSPASSHLNSVGSPSILSQLNGIGNSGNHSGQVSTMRLKKNRKVTFLSSLVESKNIFIKEEPIHGCKDLCSLSDISDHEASLEVPTALPPLTPGTNRKVNEVLKASFASWEKEVQKCNITKDPREWTEEHVIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAITPPFTGDILWEHLDILQKDCEKPNEDIVHGNSFESATTASVCGSDHQVANYPNETHANSNNSSINSRLSMDYVTSAGNSDNKNFHRATPHSHNGYNTSNTHDRINNSTPPQQQQSQQPTVNGSGSASSNNNNSMLPPAVQQSNNENNNTSSSNTNNSSNNNNNSGGSNNSNAGSNNNNNNNNNINFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPYDAQSFQSMGPQPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQNLVGHTPEELVAKYDLKIEKKDVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : * *: .*. :: : .* * * :* ***.::. :.:.***:*:.: ** *: .*.****:*** ** *: ** ***** .:::: * *.* *: ***: ** ::* *.********:****: ** :** . * : :* : **. * * *:: ..**.: .. *. : :* : : **.: . . :*: . :.*::. *: :. *.* :.. :... . * * * **:.* .:* :* **...: *::.:. *:. ....**: . : *:*: : . :.:. . : *. ** :: . : * :**************** **:****************:********** ******************************************.*:*:***** * *:* : . ", "identical_positions": 197, "similar_positions": 130, "identity": "27.44%" }, { "cls_id": "homologset.agr.HGNC:3489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZS11-1", "uniprot_id": "A0A8I5ZS11_RAT", "id": "A0A8I5ZS11-1", "name": "", "aln": "---------MSPARPALGSPGPWEASTG--HVQVGMNDFGIKNMDQVAPVANSFRGTLKRQPAFDTFDGS-------------------------------LFAVLPSLSEEQ--TLQEVPTG-------LDSVSHDSATCELP----LLTPCSKAVMSQALKATFSGFHKEQRRLGIPKNPWLWNEQQVCQWLHWATNEFSLVNVNLQRFG-MNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEEN-----------------------SHLNAVPHWINS---------------NTLGFGVEQAPYGMQAP-------SYLKDGLLDGMCPPSATPAALGSEQELQMLPKSRLNTVSVNYCSISQDFP-----------------GGNLNLLNSS---------------------------------------------------------SGK-PKEHDSPENGGD--SFESSDSLLRSWNSQSS------------------LLDVQR----------------VPSFESFEEDCSQSLCLSKPTMSFKDYIQERSDPVEQGKPVIPAAVLAG----------FTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15037-1", "uniprot_id": "ETS2_MOUSE", "id": "P15037-1", "name": "Protein C-ets-2", "aln": "-----------------------------------MNDFGIKNMDQVAPVANSFRGTLKRQPAFDTFDGS-------------------------------LFAVLPSLSEDQ--TLQEVPTG-------LDSVSHDSASCELP----LLTPCSKAVMSQALKATFSGFQKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLHQFG-MNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEEN-----------------------SHLNAVPHWINS---------------NTLGFSMEQAPYGMQAP-------NYPKDNLLDSMCPPSATPAALGS--ELQMLPKSRLNTVNVNYCSISQDFP-----------------SSNVNLLNNN---------------------------------------------------------SGK-PKDHDSPENGGD--SFESSDSLLRSWNSQSS------------------LLDVQR----------------VPSFESFEEDCSQSLCLSKLTMSFKDYIQERSDPVEQGKPVIPAAVLAG----------FTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15036-1", "uniprot_id": "ETS2_HUMAN", "id": "P15036-1", "name": "Protein C-ets-2", "aln": "-----------------------------------MNDFGIKNMDQVAPVANSYRGTLKRQPAFDTFDGS-------------------------------LFAVFPSLNEEQ--TLQEVPTG-------LDSISHDSANCELP----LLTPCSKAVMSQALKATFSGFKKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLQRFG-MNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEEN-----------------------SHLTSVPHWINS---------------NTLGFGTEQAPYGMQTQ-------NYPKGGLLDSMCP-ASTPSVLSSEQEFQMFPKSRLSSVSVTYCSVSQDFP-----------------GSNLNLLTNN---------------------------------------------------------SGT-PKDHDSPENGAD--SFESSDSLLQSWNSQSS------------------LLDVQR----------------VPSFESFEDDCSQSLCLNKPTMSFKDYIQERSDPVEQGKPVIPAAVLAG----------FTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51023-1", "uniprot_id": "PNT_DROME", "id": "P51023-1", "name": "ETS-like protein pointed", "aln": "MELAICKTDLSATKFMLPPALPSSAAIGSSSAVASTASHFLDKAAHELFQLNAINGHLFKSPASSHLNSVGSPSILSQLNGIGNSGNHSGQVSTMRLKKNRKVTFLSSLVESKNIFIKEEPIHGCKDLCSLSDISDHEASLEVPTALPPLTPGTNRKVNEVLKASFASWEKEVQKCNITKDPREWTEEHVIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAITPPFTGDILWEHLDILQKDCEKPNEDIVHGNSFESATTASVCGSDHQVANYPNETHANSNNSSINSRLSMDYVTSAGNSDNKNFHRATPHSHNGYNTSNTHDRINNSTPPQQQQSQQPTVNGSGSASSNNNNSMLPPAVQQSNNENNNTSSSNTNNSSNNNNNSGGSNNSNAGSNNNNNNNNNINFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPYDAQSFQSMGPQPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQNLVGHTPEELVAKYDLKIEKKDVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :.: : *: .* * :.** . ::. .:.:.** *.: ::* * *..:*...*. *:* *** :: :.:.***:*:.:.** :: .*.*:* *.*::* ** **.******.:**. * *:*: : :****:** ::* *.********: : *: :: .** . * :* .: *** :.: . :: * :: . :. * .. .* : .*:* : .: . . : *.: ..* * ... **. *. *. .*.* .:.*: * ..*** ** . *.* .:: :. **: . :*. . : :..*. ..: * * ***************** **:****************:********** ****************************:***************:*.***** * .:: :.:* ", "identical_positions": 194, "similar_positions": 144, "identity": "27.02%" }, { "cls_id": "homologset.agr.HGNC:349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24090-1", "uniprot_id": "FETUA_RAT", "id": "P24090-1", "name": "Alpha-2-HS-glycoprotein", "aln": "MKSLVLLLCFAQLWSCQSAPQGAGLGFRELACDDPETEHVALIAVDYLNKHLLQGFRQILNQIDKVKVWSRRPFGEVYELEIDTLETTCHALDPTPLANCSVRQQAEHAVEGDCDFHILKQDGQFRVLHAQCHSTPDSAEDVRKFCPRCPILIRFNDTNVVHTVKTALAAFNAQ-NNGTYFKLVEIS--RAQNVPFPVSTLVEFVIAATDCTGQEVT---DPAKCNLLAEKQYGFCKATLIHRLGGEEVSVACKLFQTQ-----PQPANANPAGPAPTVGQAAPVAPPAGPPES-------------------------------------------VVVGP-------VAVPLGLPDHRTH----------HDLRHAFSPVASVESASGEVLHSPK---VGQPGDAGAAGPVAPLCPGRVRYFKI-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29699-1", "uniprot_id": "FETUA_MOUSE", "id": "P29699-1", "name": "Alpha-2-HS-glycoprotein", "aln": "MKSLVLLLCFAQLWGCQSAPQGTGLGFRELACDDPEAEQVALLAVDYLNNHLLQGFKQVLNQIDKVKVWSRRPFGVVYEMEVDTLETTCHALDPTPLANCSVRQLTEHAVEGDCDFHILKQDGQFRVMHTQCHSTPDSAEDVRKLCPRCPLLTPFNDTNVVHTVNTALAAFNTQ-NNGTYFKLVEIS--RAQNVPLPVSTLVEFVIAATDCTAKEVT---DPAKCNLLAEKQHGFCKANLMHNLGGEEVSVACKLFQTQ-----PQPANANAVGPVPTAN----AALPADPPAS-------------------------------------------VVVGP-------VVVPRGLSDHRTY----------HDLRHAFSPVASVESASGETLHSPK---VGQPG---AAGPVSPMCPGRIRHFKI-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02765-1", "uniprot_id": "FETUA_HUMAN", "id": "P02765-1", "name": "Alpha-2-HS-glycoprotein", "aln": "MKSLVLLLCLAQLWGCHSAPHGPGLIYRQPNCDDPETEEAALVAIDYINQNLPWGYKHTLNQIDEVKVWPQQPSGELFEIEIDTLETTCHVLDPTPVARCSVRQLKEHAVEGDCDFQLLKLDGKFSVVYAKCDSSPDSAEDVRKVCQDCPLLAPLNDTRVVHAAKAALAAFNAQ-NNGSNFQLEEIS--RAQLVPLPPSTYVEFTVSGTDCVAKEAT---EAAKCNLLAEKQYGFCKATLSEKLGGAEVAVTCMVFQTQPVSSQPQPEGANEAVPTPVVDPDAPPSPPLGAPGL-------------------------------------------PPAGSPPDSHVLLAAPPGHQLHRAH----------YDLRHTFMGVVSLGSPSGEVSHPRKTRTVVQPSVGAAAGPVVPPCPGRIRHFKV-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PKY8-1", "uniprot_id": "A0A8M1PKY8_DANRE", "id": "A0A8M1PKY8-1", "name": "", "aln": "MRELVILAALVSALHAASLPKDSGVEYN---CQENQDNNAVLAAEQFINAHHHHGYKFRFVSQD-SRSAEKKADSCEVVFGVTLEETECHIVNPKPLDQCDRRLETETKVTAKCNVTVSSFEGKAAVKRYNCDTEPASHEDLVKKCPDCPGLLPLHEPKALESVNAALAKFNKQSNHKSYFKLMEVGRISSQWMPMGQSYFTQFAIMETNCTKKDAPQNPEACKALCGDQATYGFCKS---SKVGSEEPEVECEIYEDQN-FTHPMQHPAQSRRDCKFHDHRPGSVHPLGPDHRGHWDKGHGHRGPPERGDKKHDHGGRPEHGGRPEHAHGDKDKKPGHGGRPEHAHGDKDKKPGHEGHPEHGGRSEHAHGDKDKKHDHGGRPEHRHHDDKDKKHDHRFHPEHPCPKSPTGVPEPSPEGGRHEFPCHGYVKIPPSIYPICPFPPPRLCRGPPDLPRPTSSPKQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.**:* .:.. . * *:..*: :. *:: : :...* * :::* : *:: : . * : ::. . : : ** ** ::*.*: .*. * * * ..*:. : . :*: * :*.: * * **: * * ** * :::...:.:.::*** ** * *: : *:* *:. :* :*: * .:*.: *:*. ::.. :..*. : :****: .:*. * * * ::: * * *: . * .. * * * : * :* . . ..: : : :* .:* * * : * ", "identical_positions": 75, "similar_positions": 114, "identity": "16.2%" }, { "cls_id": "homologset.agr.HGNC:3490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50549-1", "uniprot_id": "ETV1_HUMAN", "id": "P50549-1", "name": "ETS translocation variant 1", "aln": "----------------------------------------MDG--------FYDQQVPYMVTN-SQRGRNCNEKPTNVRKRKFINRDLAHDSEE-----LFQDLS-----QLQETWLAEAQVPDNDEQFVP-------------DYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKP-QVGMRPSNPPTPSS----------------------------------TPVSPLHHASPNSTHTPKPD---RAFPAHLPP-----------------SQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDP----------------------------VYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGP--------TYQRRGSLQLWQFLVALLDDPSN-SHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41164-1", "uniprot_id": "ETV1_MOUSE", "id": "P41164-1", "name": "ETS translocation variant 1", "aln": "----------------------------------------MDG--------FYDQQVPYVVTN-SQRGRNCTEKPTNVRKRKFINRDLAHDSEE-----LFQDLS-----QLQETWLAEAQVPDNDEQFVP-------------DYQAESLAFHGLPLKIKKEPHSPCSELGSACSQEQPFKFSYGEKCLYNVSAYDQKP-QVGMRPSNPPTPSS----------------------------------TPVSPLHHASPNTAHTPKPD---RAFPAHLPP-----------------SQSIPDSTYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDP----------------------------VYEHTTMVGGAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGP--------TYQRRGSLQLWQFLVALLDDPSN-SHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMTYMPEGGCCNPHPYNEGYVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LEA3-1", "uniprot_id": "A0ABK0LEA3_RAT", "id": "A0ABK0LEA3-1", "name": "", "aln": "------------------------------------MSARGDGGQQQLHSKFVAGFICHIEKNESQRGRNCTEKPTNVRKRKFINRDLAHDSEE-----LFQDLS-----QLQETWLAEAQVPDNDEQFVP-------------DYQAESLAFHGLPLKIKKEPHSPCSELGSACSQEQPFKFSYGEKCLYNVSAYDQKP-QVGMRPSNPPTPSS----------------------------------TPVSPLHHASPNTAHTPKPD---RAFPAHLPP-----------------SQSIPDSTYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDP----------------------------VYEHTTMVGGAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQESFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGP--------TYQRRGSLQLWQFLVALLDDPSN-SHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMTYMPEGGCCNPHPYNEGYVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8MRW5-1", "uniprot_id": "ET96B_DROME", "id": "Q8MRW5-1", "name": "ETV5-related protein Ets96B", "aln": "MTISWRALSHFLIPQSDYGEAKTHLEQLQQTLTHLDHPHHHHAHHPHHHLGLYHGALPNTSTITTDSVVSCVSSTLPAVAKAISASSSCDGLQSERKKCPISDLDSGGHGHGQGHGLMEAICAGQKTSPIPPPPPPCCLTLGESSSSPNPIATAALMNASTSGSSSAGGASASLCNDLTRESSWYAHHHHHHHHHHHQLPDELVMYATPTPTPAIGKFGLDTSTEGYLNARYNVNVKGVRHDRTSSFFDIPAVTHPHNHPHPHPHPHPHPYCYRFPSSPPAGILKKSDEEATSAAVYCSDVSSGQHFPHHTKIEHADSTTTAAQQQQQQQEQQQQQQQQQQQQQHQQQLQQAAALHPHHHHSHHGHHGHQQAEQQALTHLTPLHAASAFKFSHTAVISSSAVYATPSHYAHQQQTQSQSVYRDLSPTTLAAVSDADLKYDSGPYNAAISSTYPSALRPNVVDSTTSSDAELRLDQFYASNGISTSSNGQAISQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVYRFVCDPDALFNMAYGHLTTGSGKGDQHQLTLSLAKTPP-TSGDSQTQSPRVAKSEYYDTAALHKY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : . :: .* ... . : : . ... :. :.**. : * * ** ..:. . :* . ..:.:* .* .. . *. . .* *.: . *..: :: :.* * :: * .: .***: *. . * *:. *:*. **: *. *: ... :* . ::.: * . : :: : *:* .: : : . : :*. :.*.:::..:* : *. :*:.:. : ::.. : : .: ... :..: .. * : :. . . *.::: : :* *****************:*:. : ***********************:**************************** ******:*****:***.**: . * * .: . ..* .:* : *. . .: : : *", "identical_positions": 132, "similar_positions": 160, "identity": "20.59%" }, { "cls_id": "homologset.agr.HGNC:3491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEY9-1", "uniprot_id": "D3ZEY9_RAT", "id": "D3ZEY9-1", "name": "ETS translocation variant 2", "aln": "MDLWNWDEASVQEVPPGDKLTGLEGAEFGFYFPEVALQGDTPITPMNVESCWKG-------FPELDWNPALPHEEVPFEAEP--VAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGF--------EGATGQNTATSAGGVPSWSHPPATWSTASWD------CSAGPNGSTYWDSGLGGEAQADYKMSWGGSAGSDYTTTWNSGLQN--------------------------------------------------------------------------------CSIPFEGHQIPAFATPSKSSQ-QSDRATLTPYSKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNNREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPVLACQDDMGHLPGAEGQ-----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41163-1", "uniprot_id": "ETV2_MOUSE", "id": "P41163-1", "name": "ETS translocation variant 2", "aln": "MDLWNWDEASLQEVPPGDKLTGLG-AEFGFYFPEVALQEDTPITPMNVEGCWKG-------FPELDWNPALPHEDVPFQAEP--VAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGF--------EGATGQNPATSAGGVPSWSHPPAAWSTTSWD------CSVGPSGATYWDNGLGGEAHEDYKMSWGGSAGSDYTTTWNTGLQD--------------------------------------------------------------------------------CSIPFEGHQSPAFTTPSKSNK-QSDRATLTRYSKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPVLAYQDDMGHLPGAEGQ-----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00321-1", "uniprot_id": "ETV2_HUMAN", "id": "O00321-1", "name": "ETS translocation variant 2", "aln": "MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTA--TAETCWKGTSSSLASFPQLDWGSALLHPEVPWGAEP--DSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIPAAGS--------EGAAGQNCVPVAGEATSWSRAQAAGSNTSWD------CSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAG-------------------------------------------------------------------------------GTTSLKRYQSSALTVCSEPSP-QSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ-----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29776-1", "uniprot_id": "ETS6_DROME", "id": "P29776-1", "name": "DNA-binding protein D-ETS-6", "aln": "MAILQNSRQSHKQLP---IISQTIRSAWCQQRPINAMHQDVRQKSIGSGNETKLEAKETEVPTNRRRRRRRCSSSSTSDSSA--SSYSSTDSDSGSSTSSSSIRSQLPALNLPVPLPLATPTPPAVSSPHQAPSPRRNSSDSNRSVSPVEVPVDPHAWTPEDIASWVRWATRKFKLDPEPDIDRFPKDAQELCDLSRADFWVCAGSRRGGMLLAQHFAI-------------------------------------------------------------------------------SLYHATGRETSPMLNDDEPNPYQLLNAASHRLVAQGSGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLGSYNHHAGGAMQLGRHPPPLHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFPSSSTASSQASPGQAPASSSASTSNFTAPFQGGTAGVDPARTSTSSAGNYDQGPVTPTTNAFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3ATP1-1", "uniprot_id": "A0A8M3ATP1_DANRE", "id": "A0A8M3ATP1-1", "name": "", "aln": "MAGRSRGR-WLYGANKKEALSVVSEDQSIFESPFSGPQAMHMKAEIGSPAVFRQASEESIEPTEPDWSGSAAQNSAKRAEHINGTSHESPVDCSVTKRTRHMSNSDGGQLSYQASYPEPRSSPQTATP-----------PSSTTEEKRVIVPADPEVWTQDHVRQWVDWAIKEYALSDVDVSLFQTLDGKALCKLSKEDMMRITSAYNTDILLSHLNYLRESSPTFSYPTNPTNTQPQPRVQVKAAENSFEEIGRRNSWSSSGLPAVPKGSPIEHQHNTRITEPPPRLPQDPYQALGSISSRLANPEAKPIHTKNRTTKQNSSHLPVSSTDRTVGSGQIQLWQFLLELLSDSNNSTIITWEGTNGEFKMTDPDEVAKRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGISQSHQNHSTEGSVYKFQTEG----------------------SYMQSYHSHQPKMNFISPHSTPMSVTTSNFFTPQSTYWNSATSVVYPSSPMPRHPSTHTHLNTYY-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .. :: * . : : .: . : . . . :. . . . * . . .... .. .. : .* . . . :.. . : .: .... : . . * *********** *. .:. * * * . **:: **.***: ***** **.***:****.***** ::*: * *::*:*:*. : : . ", "identical_positions": 52, "similar_positions": 72, "identity": "9.3%" }, { "cls_id": "homologset.agr.HGNC:3492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V813-1", "uniprot_id": "G3V813_RAT", "id": "G3V813-1", "name": "", "aln": "MKAGCSIVEKPEGGGGYQFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLVMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTGDVQPGRFSASSLSASCPESGGAADRKVEPSDLEDGSASDWHRGMDFMPSRNALSGGVIGHQKRKPDIMLPLFTRPAMYPDPHSPFALSPVPGRGGVLNVPISPALSLTPTMFSYSPSPGLSPFTSSSCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEESSQFSIKLQPPPAGRKNRERVESSEETTRGSVPASTPIPSRIKVEPATEKDPDSLRQSTQEKEEQAQEVDTVQTRTIEEGKGTVFAHPS--PTWPSVSISIPSDEPLEVTEDSEDRSAREPGVPEKKEDALMPPKLRLKRRWNDDPEARELSKSGKFLWNGAGPQGLATAATAAADA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4Z4-1", "uniprot_id": "ETV3_MOUSE", "id": "Q8R4Z4-1", "name": "ETS translocation variant 3", "aln": "MKAGCSIVEKPEGGGGYQFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDSHSPTGDVQPGRFSASSLSASGPESGVTTDRKVEPSDLEDGSASDWHRGMDFMPSRNALGGGAVGHQKRKPDILLPLFTRPAMYPDPHSPFAISPVPGRGGVLNVPISPALSLTPTMFSYSPSPGLSPFTSSSCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEEPSQFSIKLQPPPAGRKNRERVESREEAVRGSVPASAPVPSRIKVEPATEKDPDSLRQSTQGKEEQTQEVDSMRSRTIEEGKGTGFAHPS--PTWPSVSISTPSDEPLEGTEDSEDRSVREPGVPEKKEDALMPPKLRLKRRWNDDPEARELNKTGKFLWNGAGPQGLATTATAAADA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41162-1", "uniprot_id": "ETV3_HUMAN", "id": "P41162-1", "name": "ETS translocation variant 3", "aln": "MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTNDVQPGRFSASSLTASGQESSNGTDRKTELSELEDGSAADWRRGVDPVSSRNAIGGGGIGHQKRKPDIMLPLFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSSSCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEESTQFSIKLQPPPVGRKNRERVESSEESAPVTTPTMASIPPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKGTIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRWNDDPEARELSKSGKFLWNGSGPQGLATAAADA---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************:*******************************************************************************************.**************************************:****.************:** **. :***.* *:******:**:**:* :.****:.** :*********:****:**.**********:**:********************:*****************************************************************.:**********.********** **:. :.*: :.:*.*******:****:*****:: ***::** .:: :***** *** **:*: * ****.** **.**** *******. :**..****************************.*:*******:*******:*: * ", "identical_positions": 431, "similar_positions": 58, "identity": "83.69%" }, { "cls_id": "homologset.agr.HGNC:3493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JX95-1", "uniprot_id": "A0A0G2JX95_RAT", "id": "A0A0G2JX95-1", "name": "", "aln": "-------------------------------------------MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSE--------------------DLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENL-AFHSPTTRIKKEPQSPRTDPALSCS--RKPPLSYHHGEQCLYSSAYDSPRQIAI-----KSPAPGAPGQSPLQPFS------------RAEPQQSLLRASSSSQSHP-----GHGYLGEHSSVFQQP----------------VDMCHAFTSPQGGGRE---PLPAP------YQHQLSEPCPPYP--------------QQSFKQEYHDPLYEQAGQPAASQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFS-----------------------APSSGDGVMGYGYEKSLRP---FPDDVCIVPEKFEGDIKQEGVGAFREG-PPYQRRGALQLWQFLVALLDDPTN-AHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNHRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGP-AQPFGHKGGYSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28322-1", "uniprot_id": "ETV4_MOUSE", "id": "P28322-1", "name": "ETS translocation variant 4", "aln": "-------------------------------------------MERRMKGGYLDQRVPYTFCS-KSPGNGSLGEALMVPQGKLMDPGSLPPSDSE--------------------DLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSEN--SFHSPTTRIKKEPQSPRTDPALSCS--RKPPLPYHHGEQCLYSSAYDSPRQIAI-----KSPAPGAPGQSPLQPFS------------RAEQQQSLLRASSSSQSHP-----GHGYLGEHSSVFQQP----------------VDMCHSFTSPQGGGRE---PLPAP------YQHQLSEPCPPYP--------------QQNFKQEYHDPLYEQAGQPASSQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFS-----------------------GPSPGDGVMGYGYEKSLRP---FPDDVCIVPEKFEGDIKQEGIGAFREG-PPYQRRGALQLWQFLVALLDDPTN-AHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELTGP-APPFGHRGGYSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43268-1", "uniprot_id": "ETV4_HUMAN", "id": "P43268-1", "name": "ETS translocation variant 4", "aln": "-------------------------------------------MERRMKAGYLDQQVPYTFSS-KSPGNGSLREALIGPLGKLMDPGSLPPLDSE--------------------DLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENL-AFHSPTTRIKKEPQSPRTDPALSCS--RKPPLPYHHGEQCLYSSAYDPPRQIAI-----KSPAPGALGQSPLQPFP------------RAE-QRNFLRSSGTSQPHP-----GHGYLGEHSSVFQQP----------------LDICHSFTS-QGGGRE---PLPAP------YQHQLSEPCPPYP--------------QQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFS-----------------------GPSPGDGAMGYGYEKPLRP---FPDDVCVVPEKFEGDIKQEGVGAFREG-PPYQRRGALQLWQFLVALLDDPTN-AHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGP-AQPFGPKGGYSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PUQ1-1", "uniprot_id": "ETV4_DANRE", "id": "Q9PUQ1-1", "name": "ETS translocation variant 4", "aln": "-------------------------------------------MDYKMDG-YLDQQVPYTLAN-RSQGNGPLNRLLMATKRKYMD-AELPPQESE--------------------DLFQDLSQLQETWLTEAQVPDSDEQFVPDFHSENSVAFHSPPVKIKKEPQSPGSDPSQSCS--HKQSFSYPNGEQCLYASAYEQKRAAVAGAGGSKSSCPATP-MSPMQHYSP-------KPTVGTRQESGYMNPPSSSQSHAC---HSHSYPMNPSSRFPSGS---------------AEMCPPFAS-QGQALQRIDPAHASGGGGGGYHRQHSDPCLPYPP-------------QQTFKQEYMDPLYDRAAHINGPQP----QRFPPAHMMVKQEPTDYTYEPDVPGCPSMYHHNEGYS-----------------------NPQ--HNSEGYMFENDSR----------VVPEKFEGEVKQEGGSVFREG-APYQRRGSLQLWQFLVALLDDPSN-AHFIAWTGRGMEFKLIEPEEVARLWGIEKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALITLAFPDNQRPSLKAEFERYVNEEDTVPLSHLDEGVSYPPEPAATNMGPQPYSKGYMY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MRW5-1", "uniprot_id": "ET96B_DROME", "id": "Q8MRW5-1", "name": "ETV5-related protein Ets96B", "aln": "MTISWRALSHFLIPQSDYGEAKTHLEQLQQTLTHLDHPHHHHAHHPHHHLGLYHGALPNTSTITTDSVVSCVSSTLPAVAKAISASSSCDGLQSERKKCPISDLDSGGHGHGQGHGLMEAICAGQKTSPIPPPPPPCCLTLGESSSSPNPIATAALMNASTSGSSSAGGASASLCNDLTRESSWYAHHHHHHHHHHHQLPDELVMYATPTPTPAIGKFGLDTSTEGYLNARYNVNVKGVRHDRTSSFFDIPAVTHPHNHPHPHPHPHPHPYCYRFPSSPPAGILKKSDEEATSAAVYCSDVSSGQHFPHHTKIEHADSTTTAAQQQQQQQEQQQQQQQQQQQQQHQQQLQQAAALHPHHHHSHHGHHGHQQAEQQALTHLTPLHAASAFKFSHTAVISSSAVYATPSHYAHQQQTQSQSVYRDLSPTTLAAVSDADLKYDSGPYNAAISSTYPSALRPNVVDSTTSSDAELRLDQFYASNGISTSSNGQAISQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVYRFVCDPDALFNMAYGHLTTGSGKGDQHQLTLSLAKTPPTSGD-SQTQSPRVAKS--EYYDTAALHKY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . :* * . . : * .. :** .*:: :. *:* . * . : . * * : : .. ..*. .: *. : . * : .: : :: . :.. . .. . : .. ::.* * : . * . * .:* * . . ::* .: :: .: .. : : .: * * .* . * .. * . .* * * : . . . . : . * . ::: .:* .. :* . ****:************:*:. * ******************** **::*************************** ******:***:*:**:.:*: . : *.: .: . . ..* : * . : *. : . : *", "identical_positions": 117, "similar_positions": 127, "identity": "18.2%" }, { "cls_id": "homologset.agr.HGNC:3494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AC56-1", "uniprot_id": "D4AC56_RAT", "id": "D4AC56-1", "name": "", "aln": "------------------------------------------------MDGFCDQQVPFMVPGKSRS-----------------EDCRGRPVIDRKRKFVDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELS--------SCSHEQALGAKYGEKCLYNYCAYDRKPPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTSALAPGAGPVQG-------VGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPCRPFPPQSG-------------VPGDTRPSYQRQMSEPVVPAAPPPLQGFKQEYHDPLY-EHGVPGMP----------GPPAHGFQSPMGIKQEPRDYCADSEVPNCQSPYMRG-RYFSSNHEGFTYEKDPRLYFDD------------TCVVPERLEGKVKQEPTMYRE--------------GPPYQRRGSLQLWQFLVTLLDDPAN-AHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQ--KVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESDCPLN-EEDTLPLTHFEDS--PAYLLD-MDRCSG-LPYAEGFAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXC9-1", "uniprot_id": "ETV5_MOUSE", "id": "Q9CXC9-1", "name": "ETS translocation variant 5", "aln": "------------------------------------------------MDGFCDQQVPFMVPGKSRS-----------------EDCRGRPLIDRKRKFVDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELS--------SCSHEQALGAKYGEKCLYNYCAYDRKPPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTSGLTPGAGPVQG-------VGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPSHPFPPQSG-------------VPGDSRPSYHRQMSEPIVPAAPPPLQGFKQEYHDPLY-EHGVPGMP----------GPPAHGFQSPMGIKQEPRDYCADSEVPNCQSSYMRG-GYFSSSHEGFPYEKDPRLYFDD------------TCVVPERLEGKVKQEPTMYRE--------------GPPYQRRGSLQLWQFLVTLLDDPAN-AHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQ--KVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECPLN-EEDTLPLTHFEDN--PAYLLD-MDRCSS-LPYTEGFAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41161-1", "uniprot_id": "ETV5_HUMAN", "id": "P41161-1", "name": "ETS translocation variant 5", "aln": "------------------------------------------------MDGFYDQQVPFMVPGKSRS-----------------EECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELS--------SCSHEQALGANYGEKCLYNYCAYDRKPPSGFKPLTPPTTPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQG-------VGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPG-------------VPGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLY-EHGVPGMP----------GPPAHGFQSPMGIKQEPRDYCVDSEVPNCQSSYMRG-GYFSSSHEGFSYEKDPRLYFDD------------TCVVPERLEGKVKQEPTMYRE--------------GPPYQRRGSLQLWQFLVTLLDDPAN-AHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQ--KVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECHLS-EEDTLPLTHFEDS--PAYLLD-MDRCSS-LPYAEGFAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QC01-1", "uniprot_id": "A0A2R8QC01_DANRE", "id": "A0A2R8QC01-1", "name": "", "aln": "------------------------------------------------MDGFYDQQVPFMVPPNKS--H--------------MQEPSCRTFNDRKRKFVDTELAQDTEELFQDLSQLQEIWIAEAQVPDDEQFVPDFQSDNLMFHGPPQTKIKREMS-PSREFS--------PCGQEQRL-SPYGEKCLYNYSAFDRKPFTFNKPLTPPSTPASPFGSS-STATHPVQKRAMPPAQTQTQGAP-------LLPGPNHSSTSPHQRAQTPLHSQSPPFAVPCTPVNHPDASYSTDHRFHRQLSEPCLPFPQSDGRCQTPYPPQTRGHFPRHSRPPYQRQMSEPLVPMPP---QGFKKEMVDPRYNEQGVQNM-----------GPPRAPLFHQLSIKQEPRDFGFDSEVQNCHSSFGKSSNFYGGNGEGFGYDGEAHLYYDD------------ACVVPDRLEGKLKQEGGVFRD--------------GPPYQRRGSLQLWQFLVTLLDDPSN-GHFITWTGRGLEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVKVAGERYVYKFVCDPDALFSMAFPDNQRPSLKAEPDSLQVPEDDTVPLSHFDEANRAPYPADARDQCLVVPSFPESYTF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0S6S7-1", "uniprot_id": "B0S6S7_DANRE", "id": "B0S6S7-1", "name": "", "aln": "------------------------------------------------MDGFYDQQVPFMVPPNQKSLQ--------------VEEPYNRPVNDRKRKLVETELAQDTEELFQDLSQLQEIWIAEAQVPDDEQFVPDFQSESLMFHGPPLAKIKRELS-PSKELS--------PCSQDRSP-MPYGEKCLYSYSAYERKPSTGFKPLTPPSTPVSPCVPSNALATRPLHEQTPPPVSNTALGQR-------LLHGQPTMTKSTPNQTCVPHHSQSPPFVVPCPPLNR-ETHFSNEPRFQRQLSEPCLPFPPSDAQGRPSFMPQVACTSPRDGRPPYHRQMSEPLVPVPP---QGFKQELLDPRYVEQGVPNM-----------GPSQA-AFHPMAIKQEPRDFCFDSEVPKCQSSFGRAASFY-QNHENFSFDREQQLYFDD------------TCVVPERLEGKVKQEPSVYRE--------------GPPYQRRGSLQLWQFLVTLLDDPSN-GHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVKVAGERYVYKFVCDPEALFSMAFPDNQRPNLKADPDGLPTVDDDTLPLAHYDDG--SSYLVDGGEQCVSGMPFPDGYVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MRW5-1", "uniprot_id": "ET96B_DROME", "id": "Q8MRW5-1", "name": "ETV5-related protein Ets96B", "aln": "MTISWRALSHFLIPQSDYGEAKTHLEQLQQTLTHLDHPHHHHAHHPHHHLGLYHGALPNTSTITTDSVVSCVSSTLPAVAKAISASSSCDGLQSERKKCPISDLDSGGHGHGQGHGLMEAICAGQKTSPIPPPPPPCCLTLGESSSSPNPIATAALMNASTSGSSSAGGASASLCNDLTRESSWYAHHHHHHHHHHHQLPDELVMYATPTPTPAIGKFGLDTSTEGYLNARYNVNVKGVRHDRTSSFFDIPAVTHPHNHPHPHPHPHPHPYCYRFPSSPPAGILKKSDEEATSAAVYCSDVSSGQHFPHHTKIEHADSTTTAAQQQQQQQEQQQQQQQQQQQQQHQQQLQQAAALHPHHHHSHHGHHGHQQAEQQALTHLTPLHAASAFKFSHTAVISSSAVYATPSHYAHQQQTQSQS-VYRDLSPTTLAAVSDADLKYDSGPYNAAISSTYPSALRPNVVDSTTSSDAELRLDQFYASNGISTSSNGQAISQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQ--KVNGERYVYRFVCDPDALFNMAYGHLTTGSGKGDQHQLTLSLAKTPPTSGDSQTQSPRVAKSEYYDTAALHKY------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . :* . . . . ..::* ::* . . *. . :: .: * * : . .* : .: * *.. *..: : : ..: * **..** . . . . . *. : . * *. . . : ::* .: .:: . .. : .:* .. .: ... : *. : :.. :. : . : : * :*. :.: *: ::.. ..: : : . *************:***:*:. . *:*****:***************:************************** ** ******:*****:***.**: . *.: . .* * : .: . . : ", "identical_positions": 110, "similar_positions": 122, "identity": "16.95%" }, { "cls_id": "homologset.agr.HGNC:3495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41212-1", "uniprot_id": "ETV6_HUMAN", "id": "P41212-1", "name": "Transcription factor ETV6", "aln": "MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVP-VPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQ--------------RKPRILFSPFFHP-------------GNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRS-----------PITTNHRPSPDPEQ-RPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTR-------VIQLMPSPIMHPLILNPR--HSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVS------PPEEHAMPIGR----------IADCRLLWDYVYQLLSD--SRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQE--------------------------LDEQIYQEDEC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97360-1", "uniprot_id": "ETV6_MOUSE", "id": "P97360-1", "name": "Transcription factor ETV6", "aln": "MSETPAQSSIKQERISYTPPESPVASHRSSTPLHVHTVPRALRMEEDSIHLPTHLRLQPIYWSRDDVAQWLKWAENEFSLRPIESNKFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQ--------------RKSRMLFSPFFPP-------------GDSIHTKPEVLLHQNHDEDNCVQRTPRTPAESVHHNPPTIELLHRPRS-----------PITTNHRPSPDPEQQRPQRSPLDNMSRRLSPVEKAQGPRLQQENNHQETYPLSVSPVENNHC--------LPSSPWQESTR-------VIQLMPSPIMHPLILNPRHSHSVDFKQSRHSEDGMNREGKPINLSHREDLAYLNHIMVSMS------PPEEHAMPIGR----------IADCRLLWDYVYQLLSD--SRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQV--------------------------LDEQTYQEDEPTIASPVGWPRGNLPTGTAGGVMEAGELGVAVKEETRE--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01842-1", "uniprot_id": "POK_DROME", "id": "Q01842-1", "name": "Ets DNA-binding protein pokkuri", "aln": "------MSKMKMLPVQLS-LNSLNPGIWSDVLWRCPPAPSSQ-LAELKTQLPPSLPSDPRLWSREDVLVFLRFCVREFDLPKLDFDLFQMNGKALCLLTRADFGHRCPGAGDVLHNVLQMLIIESHMMQWHLPNSPVTPTSRYPLSPHSHPPTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNSVTLSPPPSVDSQASSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFFPENSEPNTNGRLLWDFLQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQNWNPQQQSQQQQQSPQRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAGPPPNSPALNTPSAVGGPDKFQFHPLKLENGSGSGSESAGEDLKPTDLSVSSKSTATSNEDCYPLIRNADGLTTIKLIRYNEHQVAASPAGQSPKHDDQQAGASNASSSPRPMDQASEQAQPVPMESDCNGGESEDSFRHMQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:* :. : :* .. *.. : .* : : * . :**. * :* ***:** :*::. .**.* :: : *:****** ***: ** :*.* :****:::** :: : ..* :**. * ...:*:... : ::. *.* :* ...:. .** : : * : . :.:* . . : :. .: * : ... ::.:..:* * . : . *.:* :. : . .:: * : : : :* :: .:. :::: : :*.:: * :*: : *. * .: :: *****:: ***.* .:*.::* *: ::: :*:**** ***:*** :**: .*.*:*******:**::**:** *:* ::*::.* *: . :. * : .: ::* *::: ", "identical_positions": 110, "similar_positions": 169, "identity": "14.86%" }, { "cls_id": "homologset.agr.HGNC:3496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAE2-1", "uniprot_id": "D4AAE2_RAT", "id": "D4AAE2-1", "name": "", "aln": "MYGKSLARVLPFLLSLQLTVFYPTTAVEIYTSGALEAVNGTDIRLKCTFSSFAPVGDALT-VTWNFRPRDGGREQFVFYYHMDPFRPMSGRFKDRVVWDGNPERYDVSIMLWKLQFDDNGTYTCQVKNPPDVDGLIGTIRLSVVHTVPFSEIYFLAVAIGSACALMIIIVIVVVLFQHFRKKRWAERADKSEGTKSKEEEKLNQGTKVSVYVEDTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70255-1", "uniprot_id": "MPZL2_MOUSE", "id": "O70255-1", "name": "Myelin protein zero-like protein 2", "aln": "MYGKSPALVLPLLLSLQLTALCPTEAVEIYTSGALEAVNGTDVRLKCTFSSFAPVGDALT-VTWNFRPRDGGREQFVFYYHMDPFRPMSGRFKDRVVWDGNPERYDVSILLWKLQFDDNGTYTCQVKNPPDVDGLVGTIRLSVVHTVPFSEIYFLAVAIGSACALMIIVVIVVVLFQHFRKKRWADRADKAEGTKSKEEEKLNQGNKVSVFVEDTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60487-1", "uniprot_id": "MPZL2_HUMAN", "id": "O60487-1", "name": "Myelin protein zero-like protein 2", "aln": "MYGKSSTRAVLLLLGIQLTALWPIAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDALT-VTWNFRPLDGGPEQFVFYYHIDPFQPMSGRFKDRVSWDGNPERYDASILLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRLSVVHTVRFSEIHFLALAIGSACALMIIIVIVVVLFQHYRKKRWAERAHKVVEIKSKEEERLNQEKKVSVYLEDTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PI84-1", "uniprot_id": "A0A8M1PI84_DANRE", "id": "A0A8M1PI84-1", "name": "", "aln": "-MRRMWIYLSSALCALVFTGVYQVEGMEVFTSSELEAVNGTEIRLKCTFKSNRPLSEERTSVSWSFMPLGKTKEEPFFHYQGHAYLPPGGLFKDHVVWSGDVMKGDGSITLQDVQFSFNGTYSCQVLNPPDIQGFAGEIKLRVVQKVSFSEIGILAIAVGGSIGVILLILIIYIVVRVFRRR----EEDMTVET---EDHRLKDQVL---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: :* . .:*::** *******: ******.* *:.: * *:*.* * . *: .*:*: ..: * .* ***:* *.*: : * ** * .:**. ****:*** ****::*. * *:* **:.* **** :**:*:*.: .::::::*: ::.: :*:: . . *:.:*:: ", "identical_positions": 72, "similar_positions": 66, "identity": "33.33%" }, { "cls_id": "homologset.agr.HGNC:3497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57680-1", "uniprot_id": "EVC_MOUSE", "id": "P57680-1", "name": "EvC complex member EVC", "aln": "-----MTCTKDARLQLGREALQAAPTLLVPAVLLGGVLGLGLGLWLGCRASHLRARLQKDDRKRLLGSSEPPAQSLRDTGSQAKARRRQRETTRDEDAPEVCEPSLSGNITAFALKARVVYPINQKFRPLADGSSHPSLHENLTQAAAILPHLPHQPAEASPASSLGSLSQAGKEDGSSSSSMRSTYSDDRILQCAFLRVGSFPEILACESVDIDLCVCSLHLKDLLQVDTALRQEKHLMFIQILKACLLDFFPKKKPDDELCQKVLSKQEHDLEELEKGLQARLANTEMLGTGDSGYVSLADVERKERELSEQLIDNMGAFWKQMESIQPTLMDQFKCSSSKARQFMMTLTGRMIVAEGLLHDSQDLHVLDTLERTMGRSHLARMVEFLRTQIQEETKCRLAAISRGLELLTVQGQLSGRQKEELLTQQHKAFWEEAERFGREFTQRGKDLVQASQARQAEAAAELTQTQEEERRSFLADSQLTSDPGEFLKAFHEVLERQRLTRSDQEGDEDTRITEAMAALCQELYCSTMGTFQKFVDSLFLKTLPEVTSLPVAECETLRQQVQEQAARQLGQADRFRRRQWGLLCDLLEQDKRVWLEEGTLSTVLQRQLRDHHESTIHGVLSRFSGLSEESSRGILQGHELLLCSALRRLALRGTTITALAQMRLSGKKRLLQELHEQLALEQGVSPCLEEHQWQLLRALEARIQEEAARLEDEAQQTGLRLQQQLLAEAQEAGRLLQLHMERVIGQALLVHARNVASKGRTREKEDFKRTLVETVVESVYVTSTSVNRLVQAHYQAVGKLLQAHEEQLLQRLKTLQGERINAYKLWKKQEFSDPSLESQTADGTHGASQGVQQRMLSQQKRLLDQFTKHQQGRLNSQRQKAQELDQLQAQLETQLQEAEQTLISELSTLARVPLPENKPFSNKRGLPEKPVRTKRKKPPPREREDLGTPNDDHLALADHTTGPLSTTYSASPPIRVHSGGRLDQQDSEAGDGESTSKILQKGSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V706-1", "uniprot_id": "G3V706_RAT", "id": "G3V706-1", "name": "", "aln": "-----MTCRRDARLQLGREALQAAPTLLVPAVLLGALLGLGLGLWLGCRARRLRARLQKDDTKHLLRSSEPPAQSLRDT--SSKARRRQRETTRDEDAPEVCEPSLSGNITAFALKARVVYPINQKFRPLADGSSHPSLHENLTQAAAILPHLPHQPAEASPASSLGSLSQAGKEDGSSSSSMQSTYSDDRVLQCAFLRVGSFPEILAYESVDIDLCVCSLHLKDLLQVDAALRQEKHLMFLQILKACLLECFPKKKPEEELYQKILSKQEHDLEELEKGLQARLANTEMLGTGDSGYISLADVERKERELSEQLIDNMGAFWKQMESMQPILMDQLKCSSSKARQLMMTLTGRMIVAEGLLHESQDLHVLDTLERTMGRAHMARIVEFLRTQIQEETKCRLAAISRGLELLTVQGQLSGRQKEELLTQQHKAFWEEAECFGREFMQRGKDLVQVSQAHRAEAVAELTRAQEEERRIFLADTQPTSDPEEFLKAFHEVLERQRLTRSDQEGEEDTRITEAMAALCQELYCGTMETFQKFVDTLFLKTLPEVSSLPVAECEALRQQVQEQAARQLGQADRFRRRQWGLLCDLLEQDKRVWLEECTLSTVLQRQLRDHHESTIHGVLSRFSGLSEESTRGILQGHELLLCSALRRLALRGTTITALAQMRLSGKKRLLQELHEQLALEQGVSPCLEEHQWQLLRALEARILEETARLEDEAQQTALRLQQQLLAEAQEAGQLLQLHSERAIGQALLVHARNVASKGRTRDKEDFKRTLVETVVESVYVTSTSVNRLVQVHYQGIGKLLQAHEEQLLQRLKTLQDERINAYKLWKKQEFSDPPSESQTPGGTHGAPQAVQQRMTSQRKKLLDQFTKHQQGRLNSQRQKAQELDQLEAQLETQLQEAEQTLISELATLARVPLAENKPFSNKRGLPEKPVRTKRKKPPPREREDLGLPNDDHPALADHSTGPLSAVYSASPPILVHSNGKLGQQDGEACDGENTRKILQKRSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57679-1", "uniprot_id": "EVC_HUMAN", "id": "P57679-1", "name": "EvC complex member EVC", "aln": "MARGGAACKSDARLLLGRDALRPAPALLAPAVLLGAALGLGLGLWLGCRAGRQRTRHQKDDTQNLLKNLESNAQTPSETGSPSRRRKREVQMSKDKEAVDECEPPSNSNITAFALKAKVIYPINQKFRPLADGSSNPSLHENLKQAV-----LPHQPVEASPSSSLGSLSQGEKDDCSSSSSVHSATSDDRFLSRTFLRVNAFPEVLACESVDVDLCIYSLHLKDLLHLDTALRQEKHMMFIQIFKMCLLDLLPKKKSDDELYQKILSKQEKDLEELEKGLQVKLSNTEMSGAGDSEYITLADVEKKEREYSEQLIDNMEAFWKQMANIQHFLVDQFKCSSSKARQLMMTLTERMIAAEGLLCDSQELQALDALERTMGRAHMAKVIEFLKLQVQEETRCRLAAISHGLELLAGEGKLSGRQKEELLTQQHKAFWQEAERFSREFVQRGKDLVTASLAHQVEGTAKLTLAQEEEQRSFLAEAQPTADPEKFLEAFHEVLERQRLMQCDLEEEENVRATEAVVALCQELYFSTVDTFQKFVDALFLQTLPGMTGLPPEECDYLRQEVQENAAWQLGKSNRFRRQQWKLFQELLEQDQQVWMEECALSSVLQTHLREDHEGTIRGVLGRLGGLTEESTRCVLQGHDLLLRSALRRLALRGNALATLTQMRLSGKKHLLQELREQRALEQGSSQCLDEHQWQLLRALEARVLEEASRLEEEAQQTRLQLQQRLLAEAQEVGQLLQQHMECAIGQALLVHARNAATKSRAKDRDDFKRTLMEAAVESVYVTSAGVSRLVQAYYQQIGRIMEDHEERKLQHLKTLQGERMENYKLRKKQELSNPSSGSRTAGGAHETSQAVHQRMLSQQKRFLAQFPVHQQMRLHAQQQQAGVMDLLEAQLETQLQEAEQNFISELAALARVPLAESKLLPAKRGLLEKPLRTKRKKPLPQERGDLGVPNNEDLASGDQTSGSLSSK-------------RLSQQESEAGDSGNSKKMLKRRSNL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **** ***:**:.**:**.******. ************* : *:* **** :.** . *. **: :* :: *:*: : ::*::* : ***. ..*********:*:***************:*******.**. *****.****:********. *:* *****::*: ****.*. :****.:***:** ****:***: ********::*:*******:**:**:* ***: :****.::** **:*****:**********.:*:**** *:*** *::*****:**** ******** ****** .:* *:**:*********:***** ***.***** :**:*:.**:*******:*:*:::***: *:****:*******:*****: :*:******************:*** *.*** ******* .* *::.*..*:** :****:* ***::* *:** :**:*********** :.* * :*:.* ***:.******* .*: *******:***:*** ::.** **: ***:***:** ***:::****:** *: :*****::**:** :**:*** :**:.**.**:***.*:.**:***:* :****:*** **********.::::*:********:*****:** ***** * **:*************: **::***:***** *:***:*******.*:*** * * .***********.*:*.*:::::******:*:.********:.*.****.:** :*:::: ***: **:*****.**:: *** ****:*:*. *:*..*:* :.*.*:*** **:*::* **. *** **::*:*:* :* *:************.:****::******.*.* :. **** ***:******* *:** *** **::. * .*:::*.**: :*.**:.** *. .: *:*:: ***", "identical_positions": 642, "similar_positions": 241, "identity": "63.56%" }, { "cls_id": "homologset.agr.HGNC:3498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AF72-1", "uniprot_id": "A0A8I6AF72_RAT", "id": "A0A8I6AF72-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSEEDPHEPMAPDIHEERQHRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDLQQNLESESDLREIHGNQ----DCKECDRVFPDLQSLEKHML--SHTEEREYKCDQCPKAFNWKSNLIRHQMS-HDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGK-------NHFAAGGFFGQGISLPGTPAMDKTSMVNMGHANPGLVDYFGTNRHPAGLTFPTAPGFSLSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQSNKCQSPLLTHPQILPATQDILKALSKHPPVGDNKPVELLPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDLESDKEKCKENGKMFKDKVSPLQNLASINNKKEYSNHSVFSASVEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTSGSSKLPATPATSQDQPLDLSMGSRSRASGTKLTEPRKNHVFGEKKGSNMETRPSSDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQFPLPDQRTWMSAIENMAEKLESFSGLKPEASELLQSVPSMFSFRAPPNTLPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESAGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNMEERMNGSHFKDEKALATSQNSDLLDDEEVEDEVLLDEEDEDNDIPGKPRKELGVTNLDEEIPEDDYEEAGALEMSCKVSPVRYKEEDYKSGLSALDHIRHFTDSLKMREMEENQYTDAELS-FGSSHVPEELKQPLHRKSKSQAYAMMLSLSDKDALHPTSHGSSNVWHSMARAAAESSAIQSISHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14404-2", "uniprot_id": "MECOM_MOUSE", "id": "P14404-2", "name": "Histone-lysine N-methyltransferase MECOM", "aln": "MRSKGRARKLATSNECAYGNYPEIPLEEMPDADADGITSVPSLHIQEPCSPATSSESFTPKEGSPYKAPIYIPDDIPIPDEFELRESTMPGAGLGIWTKRKIEIGEKFGPYMGEQRSDLKDSSYGWEILDEFCNVKFCIDASQPDVGSWLKYIR--FAGCYDQHNLVACQINDQIFYRVVADIAPGEELLL-------------FMKSEEDPHEPMAPDIHEERQHRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDLQQNLESESDLREIHGNQ----DCKECDRVFPDLQSLEKHML--SHTEEREYKCDQCPKAFNWKSNLIRHQMS-HDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGK-------NHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGTNRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASPPVKGLSSTEQSNKCQSPLLTHPQILPATQDILKALSKHPPVGDNKPVELLPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDLESDKEKCKENGKMFKDKVSPLQNLASITNKKEHNNHSVFSASVEEQSAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTSGPSKPSGTPATSQDQPLDLSMGSRGRASGTKLTEPRKNHVFGEKKGSNMDTRPSSDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQ---------MSAIENMAEKLESFSALKPEASELLQSVPSMFSFRAPPNTLPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESAGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNMEERMNGSHFKDKKALATSQNSDLLDDEEVEDEVLLDEEDEDNDIPGKPRKELGVTRLDEEIPEDDYEEAGALEMSCKASPVRYKEEDYKSGLSALDHIRHFTDSLKMREMEENQYTDAELSSISSSHVPEELKQTLHRKSKSQAYAMMLSLSDKDSLHPTSHSSSNVWHSMARAAAESSAIQSISHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03112-7", "uniprot_id": "MECOM_HUMAN", "id": "Q03112-7", "name": "Histone-lysine N-methyltransferase MECOM", "aln": "MRSKGRARKLATNNECVYGNYPEIPLEEMP--DADGVASTPSLNIQEPCSPATSSEAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQRSNLKDPSYGWEILDEFYNVKFCIDASQPDVGSWLKYIR--FAGCYDQHNLVACQINDQIFYRVVADIAPGEELLL-------------FMKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDFQQKLESENDLQEIHTIQ----ECKECDQVFPDLQSLEKHML--SHTEEREYKCDQCPKAFNWKSNLIRHQMS-HDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGK-------NHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPSVGDNKPVELQPERSSEERPFEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPGEVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKLTEPRKNHVFGGKKGSNVESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQ---------MSAIENMAEKLESFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLLDEEDEDNDITGKTGKEPVTSNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSALDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSTSHSSSNVWHSMARAAAESSAIQSISHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8I7Z8-1", "uniprot_id": "HAM_DROME", "id": "Q8I7Z8-1", "name": "Transcription factor hamlet", "aln": "------------------------------------------------------MDAFFKDRAQAEHILQEWVRRREPVCELDIRDS------GGVYAKTPLQRGTRYGPFPMKLSHQPNDPQLAWKAHSRHYNG---WLEPTEDVSTWLKKIRSVQDDCIGEANLQSYINAGYLWYETNRYVNAGSEMVVDGRPKSPVQLNEDFMNGGKVLAAAAAAAAAVVAASSSGAKSGGGGSSAPSDDRSDRDNGSLYSGDEFSKDKKNSSLIREGDIDFTDDENGFDIRCEVCDKVYPDLDLLDDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGPGPYRNQHVNRHHQHPHQHPLPHQPHLAATATSTCPAPPRESSESSSSAAAAAVAAMSTPPNPFLMFRTAPSFFPGFPPYGFPPFLPQNPLHPTNIPMFFSKNPMDLGCGGPEITSPVSAFDQKLPFG------FLKGENSESQAYDKVTEKELVFKAEEKLKK----------EPLVQAFEGEEDESR-SSLDIKGKLEDTRNDSKSEEQDDMKQEPERVSTPDQQQAEDDRKSIDIMSTPPPADTPSGGDGPLDLSICRKRSAG-------SFFTAPAEDNLMLHRFMPRLHEFEAERGQPLKMRKSHSSAESSTSQKSHKGSSPTPTPTASPGLTPSPSPPTSAGGELSSTSEGGAVPTMAAAAFAADHSALASGPTLP--------QTHPTFHPLLLEEIYRSG-------------------FPFLCQPG--------GRRGIEALLAGAASAAAPKRPLPPVKFSAGSVVGLKT-------------KDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHESEGNNFRDSPSSSGIAE---------REEYFDDIRKFMN----------------------------RVYTPNSLAGNEGDTEEYPNSDDQSVNLEKDSG----------------------------------------------------------------------------------------------------NFNNNSSNISNNNSSSGNNNNSSKAITISS--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. . . *. . . *.* *:.. .: :*. .: ::. :..* *.*: . : *: **:*:***: *:.*:: * :: *: *.**. * :. **:*: *:. ::*.****:*** **********: *****.*.********.********:********* **** *:*************** ** ****..*.* *** :**.**::**:.. :*. . : .** * : *: . . : .: .* ::.*.*. : * . . * :*. * : * .*: . .. : * . :.*:.:: ..* : ..**.:. :*::::. . :: . . * . :*.:::: : .. :*.*:. :* :. ::.: .:.. .: ::* * .. . .* : .. *:. *. * :.*. : : .**.* ::. : * :: * .* :::* :..:..*. : : * .. .* .. .. . :*:.. . :** *.. * * : . . . .*..: *. *:::: *** ** :* .** : * :. * . : *. *:..::: *:**:*::***:******************** ******:******************:**:*.****.**********:****. . . :.*. . * .: ** :**:*:. ..: * .:* : * :.:*:. :: .. .:.::.: ...:.**. :. ::* : ** ", "identical_positions": 265, "similar_positions": 287, "identity": "20.87%" }, { "cls_id": "homologset.agr.HGNC:3499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20934-1", "uniprot_id": "EVI2A_MOUSE", "id": "P20934-1", "name": "Protein EVI2A", "aln": "----MEHKGQYLHLVFLMTTVWASSSSGTRPNYTHLWASSVTASGSSNQNGSSRHPSDN-NTNLVTPAVGHKVSATDKPASSPPVPLASTSTLKSSTPHAFRNSSPTAE-----IKSQGETFKKEVCEENTSNTAMLICLIVIAVLFLICTFLFLSTVVLANKVSSLKRSKQVGKRQPRSNGDFLASSGLWTAESDTWKRAKELTGSNLLLQSPGVLTAARERKHEEGTEKLN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22794-1", "uniprot_id": "EVI2A_HUMAN", "id": "P22794-1", "name": "Protein EVI2A", "aln": "MPTDMEHTGHYLHLAFLMTTVFSLSP-GTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLAS-GLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.*:****.******:: *. **:.***:***.*.:: .* ** :.*: .:* *** :** *.:* .:*: * :* *.*:*.* : * .. **..*.: **:** ***:** **..* *******:*************************:******************* ***.********:*:***.**::**.*****:****.*******. ", "identical_positions": 145, "similar_positions": 52, "identity": "60.92%" }, { "cls_id": "homologset.agr.HGNC:35", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CF82-1", "uniprot_id": "ABCA5_RAT", "id": "Q8CF82-1", "name": "Cholesterol transporter ABCA5", "aln": "--------------------MATAIRDVGVWRQTRTLLLKNYLVKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVSDIELSPMDKSILSNLILGYTPVTNTTSSVMQRVSTDHLPDVLVTEEYASEKELLASSLSKPSNFVGVVFKDVMSYELRFFPDMVPVSSVYMDSRAGCSK---SCDAAQYWSSGFTALQASIDAAIIQLKTNVSLWRELESTKAVIMGEAAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKRLKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASSLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGVVEFFVTVVFGFVGLLIVLVESFPRSLVWLFSPLCQCAFLIGIAQVMHLEDFNEGALFSSLTEGPYPLIITLTMLALDSVFYALLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKNKRNYKELS---EGNINGNISLNEIVEPVSSEFIGKEAIRISGIQKAYRKKNETVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDMNFDVLTVEENLSILASVKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVRQHIPAAALLQQNDQQIVYSLPFKDMDKFSGLFSALDIHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPREEETDSKSFDEMEQSLLILSETKASLVSTMSLWKQQVSTIAKFHFLSLKRESKSVRSVLLLLLIFFAVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSTDSDINDLIDFFTQQNIIVAMFNDSDYVSAAPHSAALNVVQSEKDYVFTAVFNSTMVYSLPVMMNIISNYYLYHLNVTDTIQIWSTPFIQEITDIVFKVELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFVVLTLMLGSLFAFHHGLYFYPVKFLAVVFCLIAYVPSVILFTYIASFTFKKILNTKEFWSFIYSVTALACVAVTEITFFLGYG-VTAVFHYTFCIAIPIYPLLGCLISFIKGSWKNIPKTENAYNPWDRLLVAVIMPYLQCVLWIFLLQHYEKKHGGRSIRKDPLFRALSQKAKHKKFPEPPINEDEDEDVKAERLKVKELMGCQCCEEKPAIMVYNLHKEYDDKKDFLHSRKTTKVATKYVSFCVKKGEILGLLGPNGAGKSTIINILVGDVEPTSGKIFLGDYGSHSNEDDESTKCMGYCPQTNPLWPDITLQEHFEIYGAVKGMSSGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENL-EIDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFAKLEEAKHTFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERRQEDRVVF-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K448-1", "uniprot_id": "ABCA5_MOUSE", "id": "Q8K448-1", "name": "Cholesterol transporter ABCA5", "aln": "--------------------MATAIRDVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILVSMMHPNKKYEEVSDIELSPMDKFSLSNVILGYTPVTNITSSIMQRVSTDHLPKVIVTEEYANEKELVAASLSKSSNFVGVVFKDTMSYELRFFPEMIPVSSIYMNSREGCSK---TCDAAQYWSLGFTVLQASIDAAIIQLKTNVSVWSELESTKAVIMGEAAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKLKEFLKIMGLHDTAFWLSWVLLYASLIFLMSLLMAVIATASSLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGVVEFFVTVVFGFVGLLIVLIESFPRSLVWLFSPLCQCAFLIGIAQVMHLEDFNEGALFSNLTEGPYPLIITIIMLALDSVFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKNKRNYKELS---EGNINGNISLNEIVEPVSSEFIGKEAIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVRQHIPAAALLQQNDQQLVYSLPFKDMDKFSGLFSALDIHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPREEETDSKSFDEMEQSLLILSETKASSVSTMSLWKQQVSTIAKFHFLSLKRESKSVRAVLLLLLIFFAVQIFMFFLHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSTDSDINGLIEFFAHQNIMVAMFNDSDYVSAAPHSAALNVVRSEKDYVFSAVFNSTMVYCLPVMMNIISNYYLYHLNVTEAIQTWSTPFIQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWVGQAVVDIPLFFVVLILMLGSLFAFHHGLYFYPAKFLAVVFCLIAYVPSVILFTYIASFTFKKILNTKEFWSFIYSVTALACVAITETTFFLQYA-VTAVFHYTFCIAIPIYPLLGCLISFIKGSWKNMPKNENTYNPWDRLLVAVIMPYLQCILWIFLLQHYEKIHGGRSIRKDPFFRALSQKAKNKKFPEPPINEDEDEDVKAERLKVKELMGCQCCEEKPAIMVCNLHKEYDDKKDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENL-EIDRLQREIQYIFPNASRQESFSSILAFKIPKEDVQSLSQSFAKLEEAKRTFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLASTLWWERTQEDRVVF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWZ7-1", "uniprot_id": "ABCA5_HUMAN", "id": "Q8WWZ7-1", "name": "Cholesterol transporter ABCA5", "aln": "--------------------MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSK---SCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELS---EGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYT-IATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENL-EVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QEL5-1", "uniprot_id": "F1QEL5_DANRE", "id": "F1QEL5-1", "name": "Cholesterol transporter ABCA5", "aln": "MYFIPVSDPCGSQLKHAGRMQPLTRRDAGVWHQTRSLLYKNLLIKWRTKQQSLQELILPLLLLGLLILISTLNPHVSYGSISTKELEFERELPVKG--LGYTPITNFTNHIMEEVAR-ELSMNEHLDMFSTEADLENASLYEPEGYVGVVFLDSMSYRLRFPYSQLPLPSDFTESITSCYTNYVNCRAANYWYSGFIRLQSVIDAAIIQMKTKRPVWNELK-VRAVMMGHPGSVEVQKFPHALISIYLVLAFTPFVSFLIVNVAAEKEQRLKDTMGMMGLYDSAFWLSWGLLYAALVTTMSILMAVIATCTPLFSNSNFFVIFLLIFLYGISSIFFSFMLTPLFKKPKFASTVGSMLTVVFGCLSLFTVLMRDFPQSAVWLLCLLSPSAFSIGIAQVVYLEAQGDGAVFSSLGNGPHALYVPLVMLFLDCILYLLLAIYLDQVLPGEFGTKRSVLYFLKPSYWSKRRKRYVEVSSVYEGEVNGTPAIDESVEAVSPEFRGKEVIRICNIRKIYREKDTKVEALRGLTFDIYEGQITALLGHSGAGKSTLMNILCGICPPTEGTATIYGSPVAEIAEGAEMKQLVGICPQFNIIFDVLTVEEHLRIFAAIKGILPSDIDGEVRKVLKDLDLEKIMDALAKNLSGGQKRKLSVGIAILGDPKILLLDEPTAGMDPVSRHQVWSLLKSRRAGRVTVLSTHYMDEADILADRKAVISQGQLKCVGSSLYLKTKCGVGYHLRMSVTEGCEVEGITSLVKQHVPKAQLSRQQEAELTFTLPFESMDTFPGLFAELDCRPDLGIINYGVSMTTLEDVFLRLEAEAEVDQADYSVFNQEKVEEEGDASSMDDTDQRLLTFSDSRQDTVTGHALWRQQFSTVAWLHMLNLQRERKPIIYNLTLFVVFLSAMLILSVATGNIQ-IHSPERLFSPIYLLRRNEAPHKYTTSLLVQNSTDSDLSGFIHNLQSQDIKVEMMKKLDYMSAAPVSAAINVTGPSKDFTYILAFNSTTVHSLPMAVNVLSNALLRGYNGTGHIRTWSKPFDYQIPDKTSYALVYIEAVILGMLAAGMPAYFAMDHTRDRELKCRSTLRISGLVPSAYWCGQAAIDVPFYYLILTCMTSTLFAFHSTNLLTSHNILSVALCLIGFSPAMVLFTYCVSFMFVRVQSNRDFFSVVSMMVCVVSASIVQLALVNESASMARLLHNALCFFSPLYPLMGCLNCITVATFVQSPHDDDFL--WKNLFISVVAPYIQCILLLVSLRWLEIRYGGKTMKNDQLCR-ISSQAKSKAQRNPEENMSEDEDVQMEKARVKEAMTCQCCEEKPVVVVSNLRKQYKGKREGFSLNKKRKVATKNISFCVRKGEVLGLLGPNGAGKSTIMHMLSGDTEATAGQILMGDYGTDFQPAENPLEHVGYCPQVNPLWPRITLQEHLEIYSAIKGLRQRDIPNIIKRVVSALELKDHLYKQSKNLSAGLKRKLCFALSMLGNPQIVLLDEPSTGMDPKSKQRMWRAIRAAFKNKQRGALLTTHYMEEAEAVCDRVAIMVSGQLRCIGSIQHLKGKFGRGYSLEINLREELTGLQQVALLHKEILKIFPHAVRQDSFATMMVYKIPMEDVKSLAKSFAQLESAKQNFNFEEYNFSQSTLEQVFMEFAKEQENEEEEVGSLSTTFQWQRLRQDGPVSINHADSIVHQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *:.***:***:** ** *:* ***:.*:**:::**::* ***:* ::*: .* .:. **. : :.. *****:** *. :*:.*: .*. : ::.* :: :** :...:***** * ***.*** . :*:.* : :* .* . .* **:** ** **: *******:**: .:* **: .:**:**... **::.**:.:* ****:**:** ** :::.****:::*: : :***:*:****** ***::*: **:*******.: **.:*. :*****:****:**:**::********.*... * ::**.** :.*: :*:..**:* ***:. :. .:* ******::** .:** **.* **:.* :.: ** *:.::* ***:*****:***** :** *********** ::.* *:* **::**. ::.* :*.**.** ***.***..*:* **:* .*****.*:****************:***********:***::* *:*** *:** * * ::::***** :: ********:* *:*::*** ..:* **:*** ***:: * * **:**********:***:**:*************** *** **.*** *:*.****:***:***************** *******::**:* *:**:* * : . * .*.::***:**:* * * :*:: ::.::***:.**.*.***: ** :.:**:*.*************:**.***:********.*: *** *:.*:*: :* ** :*::: *: :**:**. *:* :*::.*:** *.: * *:::*::. ::: . .:: * :*.. :*:*: .: ****.****:***:***:..:* : *:* * *::. **:*.** ***:** ..**:.: .**** *:.**: :*::** * * * *: **.** :*.* . :*::*.:**::.:.**.****:::.::::*. : *::***:***** ***.:*:*:::::* * .:*:*** : . ::*:*.:***.: *:::**** .** * :: ..::*:*.: :..:.. ::.: ::. :: ::* ::*: *:***:*** .: :: : : : *..* ::*: **:**:* :. *: * :**:::::* : * :* ::* : :* * .*****: *: :*** * ******** ::* **:*:*..*:: : .* ***** :****:***:*************::: * ** *.*:*::::***.:. . ::. : :***** ***** *****:***.*:**: *: ::*.*:. **:**:** * *:*.**:***************:.***********::**:******:****::*.*:****************************::****.***:** ***:*:: : .* :: *::** ***:* **:**::::.:*** ***:**::** :**.**: * :***.***:******:*::****:*::. *:* :*: *:* ::* * ", "identical_positions": 826, "similar_positions": 517, "identity": "49.14%" }, { "cls_id": "homologset.agr.HGNC:3500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD58-1", "uniprot_id": "EVI2B_MOUSE", "id": "Q8VD58-1", "name": "Protein EVI2B", "aln": "MEFKYLVFIVLCQYLDNTFFSETEAITTEQQSLSTLITP-SLYVTTDSQNTAGNALSQTTRFKNISSGQQASPAQITPEQATPAVYVSSSPLTYNITRQAESAV----NNSLPQTSPSGFTLTNQ-PSPSTYNSTGQPPKHLVYTSTQQPPSPAPTSSGKPEVESTHNQPTKSTPTIYLQRDTPPPPPPPLTSEPPSGKGTAHKNNHNAIAAILIGTIIISMLVAILMIILWKYLRKPVLNDQNWAGRSPFADGETPEMCMDNIRESEASTKRASVVSLMTWKPSKSTLLADDLEVKLFESSEHINDTSNLKTDNVEVQINGLSEDSADGSTVGTAVSS-DDADLALPPPLLDLD---ENLPNKPTVTVVSPLPNDSINPQPSPDGLNQVCEEQHSKIQEPFPPPPDSFNVPLSAGDFINNQE-SAHEAQCQEFSTP-DLHPDLTDSLPPPPTELL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZM19-1", "uniprot_id": "D3ZM19_RAT", "id": "D3ZM19-1", "name": "", "aln": "MEFRYLVFMLLCQYLNSTFSSETEATTAEHRPRSTLPTPLAVHVTNDSQNTGGNTLSQTTQFNNISSGQQVPPAQTTPQQATP---------------------------SIPQTSLSGFTLTNQ-LSSSAHNSTRQPPKPLAYTSTQQPPSTAPTSSAKPVLHTTGNRPTKSTPTIYLPRDTPPPP--PLTSEPTTGKGTAHKNNHNAIAAILIGTIIICMLVAILMIILWKYLRKPVLNDQNWAGRSPFADGETPEMCMDNIRESEVSTKRTSVVSLMPWKPSKSTLLADDLEVKLFESSEHINDTNNLKTENGKDQMHGLSEDSADGSTVGTAVSSSDDADLPLPPPLLDLD---ENLSDKPTMIVVPPLPNDSTNLQPPPDGLNQVCEDHHSQINEPFSPPPDSFSVPLSE-DFVSIQE-STREAQCQEFSAP-DLNQDLMDSLPPPPPELL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34910-1", "uniprot_id": "EVI2B_HUMAN", "id": "P34910-1", "name": "Protein EVI2B", "aln": "MDPKYFILILFCGHLNNTFFSKTETITTEKQSQPTLFTSSMSQVLANSQNTTGNPLGQPTQFSDTFSGQSISPAKVTAGQPTPAVYTSSEKPEAHTSAGQPLAYNTKQPTPIANTSSQQAVFTSARQLPSARTSTTQPPKSFVYTFTQQSSSVQIPSRKQITVHNPSTQPTSTVKNS--PRSTP-----GFILDTTSNKQTPQKNNYNSIAAILIGVLLTSMLVAIIIIVLWKCLRKPVLNDQNWAGRSPFADGETPDICMDNIRENEISTKRTSIISLTPWKPSKSTLLADDLEIKLFESSENIEDSNNPKTEKIKDQVNGTSEDSADGSTVGTAVSSSDDADLPPPPPLLDLEGQESNQSDKPTMTIVSPLPNDSTSLPPSLDCLNQDCGDHKSEIIQSFPP-LDSLNLPLPPVDFMKNQEDSNLEIQCQEFSIPPNSDQDLNESLPPPPAELL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :*::::::* :*:.** *:**: *:*::. .** *. * :**** **.*.*.*:*.: ***. .**: *. *.** .:.:** . .:*. .*: .** **** :.** ***..* .* : :... .:**.:. . *.** : :..:.* *.:***:*:*******.:: .*****::*:*** ***********************::*******.* ****:*::** .**************:*******:*:*:.* **:: : *::* **************** *****. *******: .* .:***: :*.****** . *. * *** * :::*:* :.*.* **:.:**. **:. ** * * ****** * : . ** :******.***", "identical_positions": 221, "similar_positions": 120, "identity": "48.46%" }, { "cls_id": "homologset.agr.HGNC:3501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97366-1", "uniprot_id": "EVI5_MOUSE", "id": "P97366-1", "name": "Ecotropic viral integration site 5 protein", "aln": "----------------------------------------------------------------------------------------------------MVTTKMTAAFRNPNRRQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPTQSPSSPSKLSPDDLELLAKLEEQNRLIETDSK---SLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWDDVRKKKEKQVKELVRKG----------IPHHFRAIVWQLLCNAQSMTIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFK------------------EKDSLGQEVLFNVMKAYSLVDRELVTVRAVLSSLDCCCMQMPEEEAFCVFVKLMQDYRLRE---------------LFKPSMAELG-LCMYQFECMIQEYLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGGPEKLIQSAYQVKYNSKKMKKLEKEYTTIKTKEMEEQGEIKRLRTENRLLKQRIETLEK--------------------------------------------------------------------------------HKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVRTLEEHWQRHLARTS--------------------GRWKDPPKKNAVNELQDELMSIRLREAETQAEIREMKQRMMEMETQNQINSNQLRRAEQEVNSLQEKVCSLSVKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAELQQHIAELEIQKEEGKLQGQL-NRSDSNQYIRELKDQIAELTHELRCLKGQRDFSSRPPFDGIHIVSHLIGDDELFHSSDEDFIDSSLQESAIGFPLHRKSGPMSLNPALADGSESEAEDGMLGPQESDPEAPQKQPPQR-ESYSTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZM01-1", "uniprot_id": "A0A8I5ZM01_RAT", "id": "A0A8I5ZM01-1", "name": "", "aln": "------------------------------------------------------------------------MQLVFFFPFFIVLIKMPLVQQGILTFTGSASVYLAQSLRHSSCLWVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPTQSPSSPSKLSPDDLELLAKLEEQNRLIETDSK---SLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWDDVRKKKEKQVKELVRKG----------IPHHFRAIVWQLLCDAQTMPVKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFK------------------EKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLLQMPEEEAFCVFFKLMQDYRLRE---------------LFKPSMAELG-LCMYQFECMIQEYLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGGPEKLIQSAYQVKYNSKKMKKLEKEYTTIKTKEMEEQGEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQTDAARAKLEQAESTIRELQHHRH--------------------WHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVRDLEEHWQRHVARTS--------------------GRWKDPPKRNAVSELQGELMSIRLREAETQAEMREMKQRMMEMETQNQINSNQLRRAEQEVTSLQEKVCSLSLKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAELQQHIAELEIQKEEGKLQGQL-NRSDSKQYIRELKDQIAELTHELRCLKGQRDFSSRPPFDGIHIVSHLIGDDESFHSSDEDFIDSSLQESAIGFPLHRKSGPVSLNPALADGSESEAEDGVLGTQESDPEAPEKQIPQR-ESYSTTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60447-1", "uniprot_id": "EVI5_HUMAN", "id": "O60447-1", "name": "Ecotropic viral integration site 5 protein homolog", "aln": "----------------------------------------------------------------------------------------------------MVTNKMTAAFRNPSGKQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSTSLHTTSSSTTLSTPALSPSSPSQLSPDDLELLAKLEEQNRLLETDSK---SLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVHKG----------IPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFK------------------EKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRE---------------LFKPSMAELG-LCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEK--------------------------------------------------------------------------------HKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTT--------------------GRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQL-NKSDSNQYIGELKDQIAELNHELRCLKGQRGFSGQPPFDGIHIVNHLIGDDESFHSSDEDFIDNSLQETGVGFPLHGKSGSMSLDPAVADGSESETEDSVLETRESNQVVQKERPPRRRESYSTTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATD7-1", "uniprot_id": "A0A8M3ATD7_DANRE", "id": "A0A8M3ATD7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MVATDKVTGKLSSTLSWVKNSVSHTVSQMASQVATPS-SLHTTVASSTASLSSPSSASPTQLSPDDVELLAKLEEQNRLLETDSK---SLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQLKELVRKG----------VPHHFRAIVWQLLCNAQNLPIKEQYSELLKMTSPCEKLIRRDIARTYPEHEFFK------------------EKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQEYRLRE---------------LFKPSMAELG-LCMYQFECMIQEQLPELHVHFQAQSFHTSMYASSWFLTIFLTSFPLPVATRIFDIFMCEGLEIVFRVGMAILQMNQAELMQLDMEGMLQHFQKVIPHQLDSGPDKVIQAAYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIDTLEKESASLADRLIQGQVTRAQEAEENYLVKRELATVKQHIEETSVQLEQAQSTIRQLQQP----------------------FAKGNPRYTEESILQLERELVQARLKEAESQCALKEMQDKILYMEQRNTSLPDE---NNVVRLQEELIGVKLREAEALTGLKELRQQVRDLEEHWQRHLARTA--------------------GRWKDSPRKNAASELQDELMSVRLREAEAQAELRETRQRMLELETQNQIHSNQLRRAELEARNLQDRLHVLSNQNKMLHSELQETKRKQAEIECKNKEEVMAVRLREADNIAAMAELQQQISELEIQKEEGKVQGQL-NNTDSSQYIRDLKDQIADLKHEIRCLRGHQGLPNQHTFDGIHIVNHYGGDNESYQSSDEDGVKLSPHLT-----THQDRGRITLHPNLED-SESEGDE------EGD--ALRLTVPSNVSHKTTTV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RA30-1", "uniprot_id": "F1RA30_DANRE", "id": "F1RA30-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MDSLTVSSLSSTPGSELSTDEMKLLAKLEEQNRLLETDSK---SLYSVNGVLRNPTSPKTFS---------LEEN---IWENVINEWEDWSKRKVGQIKVLTRRG----------VPAHLRAMVWQLLCDSGNVSVRPQYSDLLKSSSPSETLIHRDLTRTFPHHQLFH------------------NHQSISKETLFNVLKAYSVLDQEIGYCKGSVFIVGLLLTQMAEEEAFCVFVRLMKDFRMRE---------------LYKSSRDELG-CCIYQFDSMIKEQLPELHSHFQTQGFQTSVFSSSWFYSIFLSSLPISAAMRIFDIFMCEGLEIVFRVGLAVLDMKQTELIKLDNEGMMKCLQNLES--WESNPDLMIEAAYQIKYNGSQMKQFRKDYEAIKAKELEEQEELKGLCSENKHLKHRLAILER-------------------------------------------------------------------------------------RCSEKLVSQLRKELEKTQLNIASSQNALKEMQANTSQLEEIS-AAPDE---HSVLYLRTELISCRLREAEALTELKQLKNHIKDMDEKLQQVLCGGQ--------------------QRVS-----STQNDLQVELLSTRLKETLTQAILKESRHALMQLQTQNEIHRNQLKRTEAHVSSQRDHLQELTSHNKDLHSQLQQIRCHFLAVQNKWK-----------------------------GNEDG----------DAGNLIERLQKQITELQIQIQTFS--------------------------------------------------KCAPSSCQPSTSASLEHKDT-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYY9-1", "uniprot_id": "EVI5_DROME", "id": "Q9VYY9-1", "name": "Ecotropic viral integration site 5 ortholog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MTLTTTTTASSAESQAKMDVKGGALPGEENLPTSEMDLLAKLEAANKLIESDAK---SLNSLHSTHSRKNSDTSQISLTSSGNSVAEEDIWTTWATILNDWEGALKRKNPCVSELVRRG----------IPHHFRAIVWQQLSGASDG-DKKQYAEYIKATSACEKVIRRDIARTYPEVEFFK------------------EKDGPGQEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVQIMQQHRMRH---------------MFKPSMSELG-LCMYQLENLVQEQIPDMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAMLKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNVSIDSNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDLQDRLADMKAELTALKSRGKFPG------------------------------------------AKLRSSSIQSIESTEIDFNDLN----------------MVRRGSTELST-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04322-1", "uniprot_id": "GYL1_YEAST", "id": "Q04322-1", "name": "Probable GTPase-activating protein GYL1", "aln": "---------------------------------------------------------------------------------------------------------------MNSNEDIHEERIEVPRTPHQTQPEKDSDRIALRDEISVPEGDEKAYSDEKVEMATTNASSNFGSNESAKDGESIGAFSNPHEALMQSKLREESQSKTILPSDDLSQQLETEESKVEEALKRITSPPLPPRADCIEESASALKSSLPPVLAGNKNDQ---------APLDRPQLPPRQVVNAETLHLKAPHGNATPSKSP-TSAVGNSSSSTPPTLPPRR------------------IEDPLDLAAQKHFLASTFKRNMLFYKSEDNSIKCDLDKNILNLKEDSKKINNNEIPEEVSS---------------FWLKVIGDYQNILINDIETLHFQLSRGIPAAYRLVVWQLVSYAKSKSFDPIYETYLTEMAPFDVQEFENQ-LKMMDEVPSEYVKRISNVLKAYLLFDPECEFSTDIAYIINMILDVCEEEANAFGLLVRLMKVYGLRLLFLPSASEIDILCYKFDRLVEEFYPEIHNHMVEKG-------------------------------------------------------------------------------VRSSMFLPGFFTTLFQKKLPTEIQPRIGDMVFLEGIDSIMRILATLLSNSRD--HLLKMGFDDMLELLKSGLLDAYIKQNDGTRGDTLLSNECMDKLLQDS---------------------MMKVAITPKTMKKYSSEYEEIHRLDNEKEVQYKSITEKNLHLQKHVRKLENDYTSLNREHVTIANELVKNRLNIESVLNENNGYKLQILDLKKKLDSE----------------KKKQVLGVYVPNDLKKDLEETMKKNTQVMDENLKLQDRISELERLIEEIKTANKNGT-----------------------------------------LFEYSNSKNNPLGAGWSGFKKVFK---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12344-1", "uniprot_id": "GYP5_YEAST", "id": "Q12344-1", "name": "GTPase-activating protein GYP5", "aln": "MSSDKSIEKNTDTIASEVHEGDNHSNNLGSMEEEIKSTPSDQYEEIAIIPTEPLHSDKELNDKQQSLGHEAPTNVSREEPIGISGDEDTQITEQNVNEQRQETREPSSEIDLNEPLDVEKDVTTDVQAPNGLNIEKEYDAVKENEKVYADTKEVVSSPENREVTGKNSGGEKSSSSKFLDDESGTTTAANANDISISSEVTPERSSENDNNQIHITNEVAAGINLNENKEQKAAIEDGPVTAENLSSETARKVPPIPTQIINEKGDNSSENEVSAIPTTSSPPLPPRQNVATSTSPKLPPRGKQREQPPKTKNAVPPPLEEEMKSEKFRKNFEETKRNSYHHVPLTGSKTAQLESTAEINLIASRYRKTSHHLNKEGEETRESLQEGQSFLKSTFTSFLENLSEYNEVENVNEEDREMFKIDWSFWTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMANSKSREMEDIYETLLD--TECLHEATIRRDLRRTKFVAEDKMESLYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCENEAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSPSLYNRLIREG-------------------------------------------------------------------------------ISSTMYATQWFLTFFAYKFPLEFVLRIFDIVFVEGIEVLLKFAVNLMLKNEE--TLVKLRFDELLDFLKDELFNYYLMGNQDDASVVQMGLSNGNSFKGNDDGTFSYN------VDLFVHDAMTGVYITPLTLRRYRGEYVEIHEKEQKKEDHYESLRIQNHQLQREAQKLEHDYSILNKENISAANELIQNRLNMEMLLDEKNDLINTITDIKSQIEEEIRK------------QNLPNPDASLPKADLREDLERTISRNNEVMRENGQLEERITELQAEIDELININKEQVS---------------------------------------TASLLERDSKAKGRKGWTGFKKVFK---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : :.:. . . . :.. : . . : : : .. . . : : . :.: : . . :. : . . :: : : : : . : : :: :.* : : : . :. * : : : * . ** : : : : . : . : : : : : * : : :: : . * : : .. .:: . . :. : . . :.: . : : : :: : . . : *:.::::: : : . : ", "identical_positions": 8, "similar_positions": 118, "identity": "0.75%" }, { "cls_id": "homologset.agr.HGNC:3503", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GI96-1", "uniprot_id": "A0A8I6GI96_RAT", "id": "A0A8I6GI96-1", "name": "Envoplakin", "aln": "MFKGLSKGSPAKGSPKGSPAKGSPKGSPNKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQNGAQNQALQHQQETGRNLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKIVLPPDVGPRVDWTRVLEQKQKLICEGHYGPGMAELEQQVAEHNILQREIEAYGQQLR---TLVGPDANAIRNQYRDLLKAASWRRQSLGSLYTHLQGCTKQLGALADQQGRILQQDWSDLMPDPAGVRREYEHFKQHELLAQEQSINQLEDDAERMVELGHPAIGPIQAHQEALKMEWQNFLNLCICQESQLQHVEDYRRFQEEADSASQTLAKLSSNLDTKYSFGAGDSSVSPTELLLQLEAEEKQLAIAERTIGELQRRSQEVAPLPQRRNPPKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWVVQGPGGETKSAPAACLCIPAPDPEAVAKASRLASELQTLKQKLSTEKSRLKNASAEHLQQGQQAPAGSAPADPQAQKLLSQMTQLDGDLGQVERQVLSWARSPLNDSSPLKDLEGRIQSCEGTAQHLQNLGAEKEAAQQECEAFLSTKPTGSAALQLPVVLNNVKNKYSDVHSLCYLYGEKAKAALGLEKQIQEADGIIQGFEATLAQEGPIPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKAAEHACGALQNNFQEFCQDLPRQQRQVRALTDRYHSVGDQLDLREKILQDASLTHQQLKNSRDNLSSWLEQLPHHRVQPSDGPSQIAYKLQAQKRLIQEILGREQDQATVARLTRDLQEALQEYELRADTYRCSLEPTLAVSAPKRLRVISLKENIQAQEKNLTKAYTEVAAAEQQQLHQLEFAKKMLEKKELNEDFQAIHSARQGSGSPAHTKT-ESEVLKTQLEEERKRVAEVQRELEERRQQLLQLRTQQPVARLEEKEVVEFYRDPQLKSNVLQASSRLEEEGKRRARLQAELEVVAQKVVHLEGKRKAMQPHLLTKEVTQIERDPGLDSQVTQLHNEMQGLRGENAVLAARLEGLKDELLTLEQKEINVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKEAVAKTQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNKNVMLARELQELQDKYRAVEKQKPKVQLQERVSEIFQVHPETEQEILRLRAQLQETGSKKSCVEREVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEK------------------------------------------------------------DPVLEKEAERLRQEVREAVQKRRAAEDAVYELQNKYLLLERRRPEEQIVVQEVVVTQKDPKLHEEHSRLSRSLDEEVGRRRQLELEVRQLSASVEEEEAMLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVIELHRECKGLQVEVDLLQKTKSQEKTIYKEVIRVEKDPVLESERARVWETLNRERAARQSREEDVRSLKERIDRAEALRRSWS-----LQKARDQASQDCGRLQRELRELEQQKLQKAQQLQEEGRLLSQKTESERQKAAQRSQALSQLEAAILHEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKICILEPETGNDMSPYEAYKRGIIDRGQYLQLQELECDWEEVTTSSPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHRYKDGRLPISEFALLVAGETKPSSSLSIGSIISKSPVCSPGPQSTGFFSPGLSLGLTEDSFPIAGVYDTTTDNKCSIKAAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVEQGLIENTSTQRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESVLPHLLVQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLLQDESSYEKDLTDPITKERLSYKEAMGRCHKDPLSGLLLLPAMLEGYRCYRVASPTLPRSCVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D952-1", "uniprot_id": "EVPL_MOUSE", "id": "Q9D952-1", "name": "Envoplakin", "aln": "MFKGLSKGSQGKGSPKGSPAKGSPKGSPNKHNRAATQELALLISRMQANADQVERDILETQKKLQQDRQNGEQNQALQHQQETGRNLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECSEYRALYEKMVLPPDVGPRVDWARVLEQKQNLVREGHYGPGMAELEQQVAEHNILQREIEAYGQQLR---TLVGPDANTIRNQYRELLKAASWRRQSLGSLYTHLQGCTKQLSALADQQGRILQQDWSDLMPDPAGVRREYEHFKQHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQRVEDYRRFQEEADSVSQTLAKLSSNLDTKYGFGTGDSSGSPTELLLQLEAEEKQLAIAERAVGDLQQRSQEVAPLPQRRNPSKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWLVQGPGGETKSAPAACLCIPAPDPEAVAKASRLATELQTLKQKLSTEKNRLKAAAVEHLQPGQQAPAGSAPADPQGQTLLSQMTQLDGDLGQIERQVLSWARSPLSQSSSLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQECEAFLSTKPTGSAALQLPVVLNSVKNRYNDVQSLCHLYGEKAKAALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLPHHRVQPSDGPSQISYKLQAQKRLIQEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDPGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRVEKDPVLEGERARVWEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKICILEPETGNDMSPYEAYKRGVIDRGQYLQLQELECDWEEVTTSSPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHRYKDGRLPISEFALLVAGETKPSSSLSIGSIISKSPVCSPGPQSTGFFSPGLSFGLTEDSFPIAGIYDTTTDNKCSIKAAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVERGLIENTSTQRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESVLPHLLVQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLLQDESGYEKDLTDPITKERLSYKEAMGRCRKDPLSGLLLLPAMLEGYRCYRAASPTLPRSCVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92817-1", "uniprot_id": "EVPL_HUMAN", "id": "Q92817-1", "name": "Envoplakin", "aln": "MFKGLSKGSQGKGSPKGSPAKGSPKGSPSRHSRAATQELALLISRMQANADQVERDILETQKRLQQDRLNSEQSQALQHQQETGRSLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPPDVGPRVDWARVLEQKQKQVCAGQYGPGMAELEQQIAEHNILQKEIDAYGQQLR---SLVGPDAATIRSQYRDLLKAASWRGQSLGSLYTHLQGCTRQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEDDGERMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDAKYSPAPGGPPGAPTELLQQLEAEEKRLAVTERATGDLQRRSRDVAPLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIPAPDPDAVARASRLASELQALKQKLATVQSRLKASAVESLRPSQQAPSGSDLANPQAQKLLTQMTRLDGDLGQIERQVLAWARAPLSRPTPLEDLEGRIHSHEGTAQRLQSLGTEKETAQKECEAFLSTRPVGPAALQLPVALNSVKNKFSDVQVLCSLYGEKAKAALDLERQIQDADRVIRGFEATLVQEAPIPAEPGALQERVSELQRQRRELLEQQTCVLRLHRALKASEHACAALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKNCKDNLSSWLEHLPRSQVRPSDGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAAAQQQLLQQLEFARKMLEKKELSEDIRRTHDAKQGSESPAQAGR-ESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSREELSQETQTRETNLSTKISILEPETGKDMSPYEAYKRGIIDRGQYLQLQELECDWEEVTTSGPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHLYKDGHLPISEFALLVAGETKPSSSLSIGSIISKSPLASPAPQSTSFFSPSFSLGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLSGLLLLPAALEGYRCYRSASPTVPRSLR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4X8-1", "uniprot_id": "F1Q4X8_DANRE", "id": "F1Q4X8-1", "name": "", "aln": "MFK---------------RNKDSTVKDDSKINKTQVSNLALLIARMQKNADTVEKDVLRAEELLLLDAENEKNNKTLQHQKETADLLGRAEGLLKDLFLDMDKAKKLQHPQAGEIENDVSRLHERWLKDCSLYRELYEPLN-EVELQPRINWALVLNQKQKDASKEEYGPTLADLKKQIAAHNILHKEIESYNNQLNPGSTSSQEEYAAIKKQYANLLDNSKWRRHYLNSLYDYMQDCDKEVAYMKEEQNKILKQDWSDQMVDHADVRRQYENFKNNSLLAHESEVNKLQDDGDRLIELKHPAASTVQAQRDTVRNEWQKFLNLCICQETHLDNIEEYKKYQLDADTLSESLSKLGSTVDAKSVNG-----KTSTEIQMQLQSEERPLQRNEQLLADMRKRSTTIVPLKLRRTPPSKTTTVESLCDWKTPKATLNRGELFNLKSNTDNDNWEVQSSDGTSQKFPGVCFMIPPPDPEAINRVDLLGKELEDLKKRRAALRTLQNNQQSKAPLSQAPVPAPRAEENPKAAVLANRLNQMDKDLGQVEMDTLNCIRSPLNRTDPATDLAKRLQEQEKTTAALQQLEKQRVAAQKEMEPLLSKDLNGPTSSTLLQNLSDAKNKQDSLVALNSLYKKKANASLVLERQLRQMDNTVSGFEKQLSEDGAIPDKPNAIQTRTQEIQGLKRDVAGSQNEMQKLSEDLEALKKLCSSLQQGYQEYCPDIRRQEAEVKNLQSRYSNVINQLSERERLLQEANTKHQDFQNVSQSLSLLLDNLPDNKVSPKDDLSQIQAKQNSQKRVIEDIQRKGDDMNRVVDLSKDLQNVLNEYEVNCDKYKAILDDTTVTNA-KRLHTSTLASSVAKQEKDLTKQYAETAAESDQLLKQINFAKGIVTEN--VEQVNTIQQQQQ--QQLQQKAFEDTEVLQKELKEEIAKRTNAENTLGTIKSRYLSLKSRRGIERVEEKEILQYYRDPKLQASVDDFQKKIHEEALKRTKTQSEIEVLNRKITSLESELKNTKPKLVTREVTEVERDPQLDVESTNIHESINKLSRELRVKEQEKAQLQTELKMLEQKKQNIKEKVVQKEVVRLEKDPEMLKAVRTFELDISDEGERCKSLKSEISQTKSNINSLERLIPTLEPKVVTKEVKRVEQDPVLIMESKELLNKIEEVRNENKSLMFELNNLQSRHVQIQQMKPRVEVKEIINENFRVAPETEAEMQRLRRELQDNSRQCSDFERQISFVKTEHEALRAQKPKVEYKEVVQEVVKEERSPENVREIQRLSDQVYSLQKAYNNLQNDLIRLRKDRDEWKAEKSKVETKIVTKDVTKYVDDPLQEKEVDRLRRDVREETQRRRTIEEMVFDLQNKYIQLERQKPEEKLVVQEVVRLQKDPRQILDHDRLGRSLDEEVKNRRKLELEVQQLRALIEDKEIAIRSSDEKQKKIQVETELRQIKSRIHELETAPPPIEENIVIEEVLKVERDPKLDKLTNGLRTDMDKESSDIMRLERDIRKLALDIEILQREKSVEKTIYKEVVRVEKDQALEAERSHLRDQFLQEKNVRRDLEDKLHRLQEKLQQQASKKTAMSLEETNLVHDRDKLQREKENLQRELRSLESERQNITISFQQHSRLMSERNQMNRQRSIKMESDGQRLERDILDEKDKIHKRDNIIRELKNSLQKEDS-SEMRTKEVNVSTKISILDPNTGKDMSPYDAYRQGFLDRNKYLQLQEMECDWEEITTMAPDDEILVLQDRKSGKQYSIKTALKEGKVTKYQLQQYKDGKMSISEFALLVAGEKKSSS-------------------YTPHFNSQLNQQLKEE-FPICGVYDVHTDSCVNVRSAMSRKLIDTNTAQKLLEAQAATGGIVDISNGIKYSVHKAADRGLIESSQLQRLLNAQKAFTGVEDPMTKERLSVGEAVQKGWMPKENAMRYMEAQFLTGGLVNPNKAGRVNIVDAVSSKMIDSTMMRELQEEINYAKELTDPITKEKINYKQALARCKIDPLSGLPMFNASSKNV----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.*. . .: .:: ..:*****:*** *** **:*:*.::: * * * :.::****:**. * .** ********:***::*:**** ***:*:.:**** ::*: ** *** : :: **::*: **:***: .*** :*:*::*:* ****::**::*.:**. : : :*:.** :**. :.** : *.*** ::*.* :::. : ::* :**:***** * * *.***:**:**::.**::* .:*:*:**.:*::** *** ..:*.:::::: ***:*********::*:.:*:*:::* :**: *::*:**.*.:*:* . :.**: **::**: * *: .::::** :.** **.*..:. *:*:***.: :. * :** :.* .*:* * **...* :: *..*: **.***:*: :.. *..**: **:: :: :. : : .*: :*:. * .::.::* ****:* :.* *:**. . . ** *::. * *: **.* :: :**:* *.:**. *.:: * *...**: ..: * ** :**:*:* **:*::: * : *** * :..:* ..*:* *..*:* :::: .* : * . *:* :: *.:**:.:**:* *: **: :*: * .** * :**. **:::*:* .:*:::* :.** *::** :* *.*. *** * ::***: ::* : * . *:: ** .*::**:..*.*:. *: : ...* ** :. .* ..: ***:*:* *:*.** .:* *:*::**: :: :: *:.. :. :* . : ::*.*: :*:** : :..:. * :.: *.*:::: : *:****::::****:*:..: ::.**. :*: *:::*. :*:. **.: * :*:*:*:***::**** ** : :::: .:: * * * . *: ** **::: ::***** ****::**: **:**.:::.*::.::. * * :. ::: ::.*:.**: *.::****:.****:***** *: *:..* . :** :.:* * **.:*:.:: ::: :*:*:::* : * *:* **** *: **: :**: . : * .*:::. : .: *.****** ******.****:.*: **: ***.:***::*** .*:**: *: *::**.* : ***::***::****** ****: :*.**. ****** .**:*****:** * :*::* : .:::.**: .* ****:. :*:***. **.::*:*::***:*:*:**.*:: *:.** ::*:*.. : .*.*: : * :::::**: ** ********:**:** .** **::: : : :*: .*: *:. : *:*:::: : : * * : **: .:: .**::** ** :: : : .:*:..:*:*::.: :**:: : . :** ** ***:*::::. :*:*: .:.:*: .* :*:*.*:****.**:*:**:*****:**::*.:**.:******:******:** .* .* ** **********::**: :::* : : ****::.***********.*.** * .*.. :. * :: ***.*:**. **. .:::*::::::*. *.***************: . :****** ::****.:. ************:***:*::*******:******:*..: :: .*.*****::*:::**: : :*: . **.. : : **:* .* *:*****:**::.**:*:.**: ****** :: * :. ", "identical_positions": 766, "similar_positions": 713, "identity": "37.59%" }, { "cls_id": "homologset.agr.HGNC:3506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQ30-1", "uniprot_id": "F1LQ30_RAT", "id": "F1LQ30-1", "name": "Homeobox even-skipped homolog protein 1", "aln": "MESRKDMVMFLDGGQLGSLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQ-PSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPDSDALGSSPNSGSEAPKSNGGSGGSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHP---ADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRP----------------------LDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAG-----GPCSCLACHSG--------PSNGLAPR---AAAASDFTCASTSRSDSFLTFAPSVLSKASSVA----LDQREEVPLTR-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23683-1", "uniprot_id": "EVX1_MOUSE", "id": "P23683-1", "name": "Homeobox even-skipped homolog protein 1", "aln": "MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQ-PSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPGSDALGSSPTSGSEAPKSNGGSGGSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHP---ADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRP----------------------LDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAAAAAAAGPCSCLACHSG--------PANGLAPRAAAAAAASDFTCASTSRSDSFLTFAPSVLSKASSVAA---LDQREEVPLTR-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49640-1", "uniprot_id": "EVX1_HUMAN", "id": "P49640-1", "name": "Homeobox even-skipped homolog protein 1", "aln": "MESRKDMVVFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQ-PSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHP---ADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSLRP----------------------LDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAG-----GPCSCLACHSG--------PANGLAPR---AAAASDFTCASTSRSDSFLTFAPSVLSKASSVA----LDQREEVPLTR-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IVI8-1", "uniprot_id": "A0A0R4IVI8_DANRE", "id": "A0A0R4IVI8-1", "name": "", "aln": "MDSAKEIMMRAEGSQVGTLSAKTGSNLTEAPGDPLRKLPDKPITQNRLSPLPYSQSS------------VD-----DATKGHRSAKYGDVTLSSKPSLPDIDLSDIPNKDASSSDAESDLYEEIDVSCTPES----MDYPNGQG----LAMGSPKHGKEVGVDKIGS----VPGSLNY-GSDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHP---ADPAFYTYMMSHAAATGSLPYPFQSHLPLPYYSPLSSVTAGSATATAGPFSNPLRS----------------------LDSFRVLSHPYPRPELLCAFRHPSLYPSPGHGLGPGGS------PCSCLACHASS-------QTNGLQHR----SNNAEFSCSPTTRTEAFLTFSPAVISKSSSVS----LDQREEVPLTR-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06602-1", "uniprot_id": "EVE_DROME", "id": "P06602-1", "name": "Segmentation protein even-skipped", "aln": "--------------MHGYRTYNMESHHAHHDASPVDQ---KPLVVDLLATQYGKPQT--------------------------------------PPPSPNECLSSPDN-----------------------------------------SLNGSRGSEIP------------------ADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHPHMMGSSATGSSYSAGAAGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSAPSVPAPAPLTTTSPLPAPGLLMPSAKRPASDMSPPPTTTVIAEPKPKLFKPYKTEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *: :. ..*: : * : . *:. : *. . : . .: . . *.* .. .:*********:*:.*******:************** *****:*****************:*::**:. :**** : ::. ** : .:*** : . . :. . ::.. *:. * . : .::: ::* * ::** : ... * . ... . .. :*::. : * : . : :: :.. .: : ..* ..:.**. * . :* . ", "identical_positions": 87, "similar_positions": 103, "identity": "17.76%" }, { "cls_id": "homologset.agr.HGNC:3507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACC8-1", "uniprot_id": "D4ACC8_RAT", "id": "D4ACC8-1", "name": "Homeobox even-skipped homolog protein 2", "aln": "MMERIRKEMILMERGLHSPTAGKRFSNLSDSSGSAVLEALENSQHPARLSPRLPSAPLHGALGDLPAKGKFEIDTLFNLQHPSSESTVSSEIASATESRKKPSHYSEAAAEADMSSDVEVGCSALRSPSGLGAAQLKENNAKGYAESGSVAGTTTSATGSGLGSLHGGGGG-NSGGAALGGSGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHP---ADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPATAAG--LNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGSGGGGGGG----AGTAGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49749-1", "uniprot_id": "EVX2_MOUSE", "id": "P49749-1", "name": "Homeobox even-skipped homolog protein 2", "aln": "MMERIRKEMILMERGLHSPTAGKRFSSLSDSAGGAVLEALENSQHPARLSPRLPSAPLHGALGDLPAKGKFEIDTLFNLQHPSSESTVSSEIASATESRKKPSHYSEAAAEADMSSDVEVGCSALRSPSGLGAAPLKENNAKGYTESGSVAGTTTSASGSGLGSLHGGGGGGNSGAAALGGSGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHP---ADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAG--LNSAASAAAAAAAAAAAASSAAAAGAPPSGSSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGSGGGGGGG----AGTAGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03828-1", "uniprot_id": "EVX2_HUMAN", "id": "Q03828-1", "name": "Homeobox even-skipped homolog protein 2", "aln": "MMERIRKEMILMERGLHSPTAGKRFSNLSNSAGNAVLEALENSQHPARLSPRLPSAPLHSALGELPAKGKFEIDTLFNLQHTGSESTVSSEISSAAESRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAAQLKENNGKGYAESGSAAGTTTSASGSGLGSLHGGSGG-SGGSAALGGSGS--GADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHP---ADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAG--LNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06602-1", "uniprot_id": "EVE_DROME", "id": "P06602-1", "name": "Segmentation protein even-skipped", "aln": "---------------------------------------------------------------------------MHGYRTYNMESHHAHHDASPVDQK----------------------------------PLVVDLLATQYGKPQTPPPSPNECLSSPDNSLNGSRGS------------EIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYP--PYAPAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHPHMMGSSATGSSYSAGAAGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFD-RSPVAQSAPSVPAPAPLTTTSPLPAPGLLMPSAKRPASDMSPPPTTTVIAEPKPKLFKPYKTEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : . ** : . :*..:.: . : : .. * :. : . :.... .* .**:*. *. . . .**********:*:.*******:************** *****:*****************:*::**:. :**:* : :: ** : .:*** .:.* . ...:*.*: . : . .. . * .::: . .** . : : * **. .** :: . .::*:.:: :*.:*. ** **. . . :. .:*:.. ::::. .* . . *.. . .. . * . .*.** : :. ** .. ::..: ...* .. * ", "identical_positions": 103, "similar_positions": 136, "identity": "20.6%" }, { "cls_id": "homologset.agr.HGNC:3508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01844-1", "uniprot_id": "EWS_HUMAN", "id": "Q01844-1", "name": "RNA-binding protein EWS", "aln": "-MASTDYSTYSQAAAQQGYSAYTAQPTQ-GYAQ-TTQAYGQQS-YGTYGQPTDVSYTQAQ-TTATYGQTAYATSYGQPP------TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTT---QASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ-PPTSYPPQTGSYSQ-APSQYSQQSSS---YGQQ--------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGG--RGGG-RGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-GRGGDRGGFPPRG-PRGS-RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQER--RDRPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140UHY3-1", "uniprot_id": "A0A140UHY3_RAT", "id": "A0A140UHY3-1", "name": "RNA-binding protein EWS", "aln": "-MASTDYSTYSQAAAQQGYSAYTAQPTQ-GYAQ-TTQAYGQQS-YGTYGQPTDVSYTQAQ-STATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTT---QASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPAETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSSQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ-PPTSYPPQTGSYSQ-APSQYSQQSSS---YGQQ--------SSFRQDHPSSMGVYGQESGGFSGPGENRSLSGPDNRGRGRGGFDRGGMSRGG--RGGG-RGGMGSAGERGGFNKPGGPMDEGPDLDLGLPIDPDEDSDNSAVYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPLNSMRGGMPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-GRGGDRGGFPPRG-PRGS-RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQER--RDRPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61545-1", "uniprot_id": "EWS_MOUSE", "id": "Q61545-1", "name": "RNA-binding protein EWS", "aln": "-MASTDYSTYSQAAAQQGYSAYTAQPTQ-GYAQ-TTQAYGQQS-YGTYGQPTDVSYTQAQ-TTATYGQTAYATSYGQPP------TGYSTPTAPQAYSQPVQGYGTGTYDSTTATVTTT---QASYAAQTAYGTQPAYPTYGQQPTATAPTRPQDGNKPAETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSSQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ-PPTSYPPQTGSYSQ-APSQYSQQSSS---YGQQ--------SSFRQDHPSSMGVYGQESGGFSGPGENRSLSGPDNRGRGRGGFDRGGMSRGG--RGGG-RGGLG-AGERGGFNKPGGPMDEGPDLDLGLPIDPDEDSDNSAIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGMPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-GRGGDRGGFPPRG-PRGS-RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQER--RDRPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J1A5-1", "uniprot_id": "A0A0B4J1A5_DANRE", "id": "A0A0B4J1A5-1", "name": "", "aln": "MASAADYNSYGQAGSQQGYGSYPAQPSQPGYGQGTQQSYGQQQGYGSYSQPADSTYSQTSGSSSSYGQQPYGSSYGQQPPASG--SYNAASATPQGYTQPVQGYGSSSYDSSTAAASSTSNTQTSYGGQASYGTQSAYPGYGQQPAAAAP--------------PSSYSSGSQQP-AGYEQS--SYSQQP--------------QQSTYSQQQQGGYQ----GQQGGYGQQSSYSQQGGYQQTPPQQQQAPPSSYAPPSGSYGQPSASQYGQQGSTGGGYGQSDYKPPNQYGSYRPDHQNGGGYSGPESGGYGGPGEGRGMGGGENRGRGRGGFDRGMMRGGGGMRGGMSRGGMGIAGDRGGFSKPG-------DGEMGAPEEQD-DSENSTIYITGLTENATLEEVADFFKHSGIIRINKRTGLPAVNIYTDKDTGKPKGDATLSYEEPPSAKAAVEWFDGKDFQGKKLKVSMARRKPMMGMMRGGMP----------MRGDRGGMMGRGGMMGRGGMGRGGDRGGFMPRGGPRGMGRGGPTGG-NMQQRAGDWQCPNAGCGNQNFAWRMECNQCKAPKPEGFGPPPFPP-GGDRGRGGPGGMRGGRG--MDRGGPGGPGGFRGGRGVDRGGFRG-RGMDRGGFGGRGRGGP------PMDDMGRRGRGMGPPGKMDMKGDHRQDR--RERPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27294-1", "uniprot_id": "CAZ_DROME", "id": "Q27294-1", "name": "RNA-binding protein cabeza", "aln": "-MERGGYG----GGSGQGYNNFAVPPPN---------------------------YQQMPNKTGNYNEPP--------------------------------------------------------------------PNYGKQ--------------------------------------------------------------------------------GGGYDSGSGHRGSGGSGNGGG------------GGGSWNDRGGNSYGNGGAS-----------------------------------------------KDSYNKGHGGYSGGGGGGGG---GGGGGSGGN-----------------------------DMITQEDTIFVSGMDPSTTEQDIETHFGAIGIIKKDKRTMKPKIWLYKNKETGASKGEATVTYDDTNAAQSAIEWFDGRDFNGNAIKVSLAQRQNNWNKGGGGGGGGGGRGGFGGRRGGGGGGGGGGGGGGRFDRGGGGGGGRY-----DRGGGGGGGGGGGNVQPRDGDWKCN--SCNNTNFAWRNECNRCKTPKGDDEGSS----GGGGGGGYGGGGGGGGYDRGNDRGSGGG-----GYHNRDRGGNSQGGGGGGGGGGGYSRFND--------NNGGGRGGRGGGGGNRRDGGPMRNDGGMRSRPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*. ..: ***. :.. *.: * * .:..*.: . * **:* . *.. *.: ... : **:.: . ..*.: .:: :. .:*:**:. * ** ** .* . * :::.:::: *: ..* ::: .* *::: :*** * : :* :*:** .**:**::*::. :*::*:*****:**:*. :***:*::: . ** **. ** * ** ** . * **. * : ** *. ** *:* * ***:* .*.* ***** ***:**:** :. .. **. * * ** ** . ***. ** * :. **** * . ** ** * . :: * * * *: * *:: *.***", "identical_positions": 133, "similar_positions": 119, "identity": "19.16%" }, { "cls_id": "homologset.agr.HGNC:3511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4W8-1", "uniprot_id": "A0A0G2K4W8_RAT", "id": "A0A0G2K4W8-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKEASEPVNVKKYKGQAVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSYGVKPILVFDGCTLPSKKEVERSRRERRQSNLLKGKQLLREGKVSEARECFTRSVNITHAMAHKVIKAARALGVDCLVAPYEADAQLAYLNKAGIVQAVITEDSDLLAFGCKKVILKMDQFGNGLEVDQARLGMCKQLG--DVFTEEKFRYMCILSGCDYLASLRGIGLAKACKVLRLANNPDIVKVIKKIGHYL-KMNITVPEDYITGFIRANNTFLYQLVFDPIQRKLIPLNAYGDDVNPETLTYAG--QYVNDSVALQIALGNRDINTFEQIDDYS---PDT-MPAHSRSHSWNDKACQKSPVASSIWHKNYCPRLEVNSVSHAPQLKEKPSTVGLKQVISTKGLNLPRKPCVLKRPR-NEALSEDDLLSQYS-SLTKKIRENSCGNGTSPNSSEMSVPCPDGGTAHKTDAHTPSRTRNKFATFLQRRNEECGAIVVPGTKSRFFCSSPDFDNFIPKKGSNQPPNETVATGKATTSLLGALDCPDTGGQKPVVTNGTHS-----PNTHIPGD-----ATGSPKDEAQSSETSKFLGTMSPPTLGTLRSCFSWSGTLGEFSRTPSPSTRSTLQQFRRKSEPPACLPEACAVT-DVCDSKSGTLGDKSQSLHELDWSSRSQESIDSTCS-LNTSSLSQPSSKDSDSEESDCNNKSLDNQGSQNSKQHLPHFPK-----KDILGRNKVPGLCRSSSMDSLSATKIKPLVPARVSGLSKKPGSIQKRKHHDAENKPGLQIKISELWKNFGFKKDSEKLPSCKK--PLSPVKDNIQLTP-ETEDEIFNKPECARAQRAIFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ11-1", "uniprot_id": "EXO1_MOUSE", "id": "Q9QZ11-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIQEASEPVNVKKYKGQAVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSYGVKPILIFDGCTLPSKKEVERSRRERRQSNLLKGKQLLREGKVSEARDCFARSINITHAMAHKVIKAARALGVDCLVAPYEADAQLAYLNKAGIVQAVITEDSDLLAFGCKKVILKMDQFGNGLEVDQARLGMCKQLG--DVFTEEKFRYMCILSGCDYLASLRGIGLAKACKVLRLANNPDIVKVIKKIGHYL-RMNITVPEDYITGFIRANNTFLYQLVFDPIQRKLVPLNAYGDDVNPETLTYAG--QYVGDSVALQIALGNRDVNTFEQIDDYS---PDT-MPAHSRSHSWNEKAGQKPPGTNSIWHKNYCPRLEVNSVSHAPQLKEKPSTLGLKQVISTKGLNLPRKSCVLKRPR-NEALAEDDLLSQYS-SVSKKIKENGCGDGTSPNSSKMSKSCPDSGTAHKTDAHTPSKMRNKFATFLQRRNEESGAVVVPGTRSRFFCSSQDFDNFIPKKESGQPLNETVATGKATTSLLGALDCPDTEGHKPVDANGTHN-----LSSQIPGN-----AAVSPEDEAQSSETSKLLGAMSPPSLGTLRSCFSWSGTLREFSRTPSPSASTTLQQFRRKSDPPACLPEASAVVTDRCDSKSEMLGETSQPLHELGCSSRSQESMDSSCG-LNTSSLSQPSSRDSGSEESDCNNKSLDNQGEQNSKQHLPHFSK-----KDGLRRNKVPGLCRSSSMDSFSTTKIKPLVPARVSGLSKKSGSMQTRKHHDVENKPGLQTKISELWKNFGFKKDSEKLPSCKK--PLSPVKDNIQLTP-ETEDEIFNKPECVRAQRAIFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ84-1", "uniprot_id": "EXO1_HUMAN", "id": "Q9UQ84-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLG--DVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYL-KMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAG--QYVDDSIALQIALGNKDINTFEQIDDYN---PDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPR-SAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSS-DSTDCVSNKVSIQPLDETAVTDKENN--LHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSE-ESSDDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSK-----KDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNFGFKKDSEKLPPCKK--PLSPVRDNIQLTP-EAEEDIFNKPECGRVQRAIFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803U7-1", "uniprot_id": "EXO1_DANRE", "id": "Q803U7-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKDASEPMHVKKYRGQTVAVDTYCWLHKGAFSCAEKLAKGEPTDQYVSYCMKFVDMLLSFGVKPILVFDGRNLPSKQEVEKSRRERRQANLQKGKQLLREGKITEARECFTRSVNITPSMAHDVIRAARTRGVDCVVAPYEADAQLAFLNKSDIAQAVITEDSDLLAFGCKKVILKMDKQGNGLEIEQCHLGRCKSLG--NIFTEEKFRYMCILSGCDYLQSLYGIGLGKACKLLRMANNPDILKVIKKMGQYL-KMDISVPEEYIEGFTKANNTFLYQLVFDPLRRKVVPLNPYPDHINPAALSYAG--TNVGDEKGLQMALGNLDINTMQRIDDFNPDAPQTQPPKAPRSSSWNDRCDKTATTQASIWSQNYEPGCTKSQSPTSP--KRPPPTRGKERIVSVQSLKLPQRESQVKRPREDTSLSVDDLLEQYTAGVKRHCPETQPTTKPLTNDNKVSKENHCGSTSG------PFRPRNRFATLLQWRNRSEEGTEEQGTCSRFFCHD-ESNIAETQEDSKQDSSQSVES--------QEKHVSQSGGDTSSLCEEPER---------------------EQDKDEPSSPPASPSCSSRPASVG--LGVFSWSGTTKELNKSVSHPARDSTERQR-SSSTPSGLSTLQQFHRNKARISWAGPG-LSLSSSPVEGSEDAGNSPGSPPS-QDSAYFSQSSSISASVENSLVTEDNSDKEKERDSVVSNSPSSSPLDRLKPAVNRTKVSGLSRKGACGQGKGGKIETSAPARASGLRRKPS---GKKNVNNENSPGLQATISGLWGAFSFKKDSPKLSATKKGEPMSPVGENVVMETTQADKEIFIIAE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39875-1", "uniprot_id": "EXO1_YEAST", "id": "P39875-1", "name": "Exodeoxyribonuclease 1", "aln": "MGIQGLLPQLKPIQNPVSLRRYEGEVLAIDGYAWLHRAACSCAYELAMGKPTDKYLQFFIKRFSLLKTFKVEPYLVFDGDAIPVKKSTESKRRDKRKENKAIAERLWACGEKKNAMDYFQKCVDITPEMAKCIICYCKLNGIRYIVAPFEADSQMVYLEQKNIVQGIISEDSDLLVFGCRRLITKLNDYGECLEICRDNFIKLPKKFPLGSLTNEEIITMVCLSGCDYTNGIPKVGLITAMKLVRRFNTIERIILSIQR-----EGKLMIPDTYINEYEAAVLAFQFQRVFCPIRKKIVSLNEIPLYLKDTESKRKR--LYACIGFVIHRETQKKQIVHFDDDIDHH----------------------LHLKIAQGDLNPYDFHQPLANREHKLQLASKSNIEFGKTNTTNSEAKVKPIESFFQKMTKLDHNPKVANNIHSLRQAEDKLTMAIKRRKLSNANVVQETLKDTRSKFFNKPSMTVVENFKEKGDSIQDFKEDTNSQSLEEPVSESQLSTQIPSSFITTNLEDDDNLSEEVSEVVSDIEEDRKNSEGKTIGNEIYNTDDDGD----------------------GDTSEDYSETAESRVPTSSTTSFPGSSQRSISGCTKVLQKFRYSSSFSGVNANRQPLFP-------------------RHVNQKSRGMVYVNQNRDDDCDDNDGKNQITQRPSLRKSLIGARSQRIVIDMKSVDERKSFNSSPILHEESK-------------------------------------------------KRDIETTKSSQARPAVRSISLLSQFVYKGK----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12086-1", "uniprot_id": "DIN7_YEAST", "id": "Q12086-1", "name": "DNA damage-inducible protein DIN7", "aln": "MGIPGLLPQLKRIQKQVSLKKYMYQTLAIDGYAWLHRASCACAFELVMNKPTNKYLQFFIKRLQLLKRLKIKPYIVFDGDSLFVKNHTETRRRKKRLENEMIAKKLWSAGNRYNAMEYFQKSVDITPEMAKCIIDYCKLHSIPYIVAPFEADPQMVYLEKMGLIQGIISEDSDLLVFGCKTLITKLNDQGKALEISKDDFSALPENFPLGELSEQQFRNLVCLAGCDYTSGIWKVGVVTAMKIVKRYSEMKDILIQIER-----TEKLCFSKAFKQQVEFANYAFQYQRVFCPLSNQITTLNNIPKAVTNSHAEIIK--IMKCIGSVVERGSGVRKDVINTKNIDHK----------------------VHEMIAKGELHPVDMASKLINRE----------------------------------------------------------------RKLKARKLFKVGLLGGESNSFNK--------------------------KVEQPLVDT-----------------------------QDVLSERENSLDNKNASSIYMT-----------------------------------------------------SPAAISGTVPSIF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q24558-1", "uniprot_id": "EXO1_DROME", "id": "Q24558-1", "name": "Exonuclease 1", "aln": "MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDTDVYIQYCLKYVNMLLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRCVDVTHDMALRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNGSGLLVEAEKLHLAMGCT-EEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQEDMRIALKKIPSYLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALEDYETDERYCSNAGTLLEDSEQALHLALGNLNPFSMKRLDSWTP------------EKAWPTPKNVKRSKHKSIWQTNFQSENTHTPKKENP---CALFFKKVDFVGKTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRRSPSREDSVDQERTPPPSPVHKSRHNPFAKERTGEEANQRSPVVCENASLLRLLSPKKASPLDGEAGVKKVDSLKRSIFAKEQVQIRSRFFATQDEQTRLQREHLRDTENDDMDEQKLSSHSGHK------------------------------KLRLVCKDIPGKNPIRQRCSSQISDGETDTDTTASSLLESQDKGVPSPLESQEDLNNSQPQIPTEGNTNSTTIRIKSLDLLLENSPEPTQESDRNNNDAIILLSDDSCSSDQRASSTSSSSQQRQNFLPTSKRRVGLSKPST-----------------------------------------------AKKGTPKSRTNGKLGAVSQNQTKLSMFGFQTKPVLK------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **: : .. : :: ..:*:* *.***:. .** :*. .: *: *: : :* ..:* ::* ::*** : * .* **. * . . .* *. :* . : :.:::* ** :* .: .: :***:***.*:.:*:: .: * :*:***** **.: :* *:: *. * : : ::: : *:**** .: :*: .* *.: . . : .: . . : * :* . :: *: .:: * :. . . . . . . *. ", "identical_positions": 68, "similar_positions": 107, "identity": "7.84%" }, { "cls_id": "homologset.agr.HGNC:35118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2F1-1", "uniprot_id": "A0A0G2K2F1_RAT", "id": "A0A0G2K2F1-1", "name": "", "aln": "MLISVVSIPPAAGGPRPEPSPGPPPPLLPKPGKDNQRLQKLLRKAARKKMVGTVPTPPGAFRTSLSPVSEASHDLETPVLCP-------------AEAPHTVAPLPRSPHTPIIHHVASPLQKSTFSFSLPQQRSLATHFKASP------------------------------NLEAPAPETACPRGGFAHVSAPTVGGTHITQVHIRLSPSSHIG---------------------------------------------------------------------------------------------TSESPRMA-------LDGDKSLCTSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------TQSLIPVAHIRPLPTGVQSVSPGPEEPPITRPPSSFQASINRESGAR---------------VVVPIAPTYRSPGPSPYSPAS--------AAPETKYPEELPTARPAMEPNHVSSLPGASG---------------------------------PSGPQPRPAPKVAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------KPSLSGWTRLKKQLMEDAKEPAFPEPELNLESTQP---------EVPAP--------MGPQPPVSRASRMWDAVLYRMSLSESHRGQPVGSGDRGHP-------------PTCLSRLPFLCR-PRFNARKLQEVVRPPPTFHPILELH---------SQPKNFNRTAAGWRLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C494-1", "uniprot_id": "PRR33_MOUSE", "id": "Q8C494-1", "name": "Proline-rich protein 33", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA-------LDGDKSLCTSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------TQPLIPVAHIRPLPAGVQTVSPRPEEPSITRPPPSFQASVNRESGAR---------------VVVPIAPTYRSPGPSPYSPPP--------AAPEAKHVEEPPTARPAMEPRNVSSLPGASG---------------------------------PSDLHPYPVPKVAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------KPSRSGWTRLKKQLMEEAKEPAFPELKPNLEPMQP---------EVPAPV-------VGLQPPASRASRMWDAVLYRMSLAESHRDHPVGPGDRGHP-------------LACLNRLPFLCR-PRFNARKLQEVVRPPPTFHPILELH---------SRPKNFNRTAEGWRLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MZF0-1", "uniprot_id": "PRR33_HUMAN", "id": "A8MZF0-1", "name": "Proline-rich protein 33", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MGP------------------------------QVVASAPEPTRPPSGFVPVSGG--GGTHVTQVHIQLAPSPHNG---------------------------------------------------------------------------------------------TPEPPRTAPEVGSNSQDGDATPSPPR-------------------------------------------------------------------------------------------------------------------------------------------------------------------AQPLVPVAHIRPLPTTVQAASPLPEEPPVPRPPPGFQASVPREASAR---------------VVVPIAPTCRSLESSPHSLVP--------MGPGREHLEEPPMAGPAAEAERVSSPAWASSPT------------------------------PPSGPHPCPVPKVAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------KPRLSGWTWLKKQLLEEAPEPPCPEPRQSLEPEVPTPTEQ----EVPAPTEQEVPALTAPRAPASRTSRMWDAVLYRMSVAEAQ-GRLAGPSGGEHT-------------PASLTRLPFLYR-PRFNARKLQEATRPPPTVRSILELS---------PQPKNFNRTATGWRLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAA1-1", "uniprot_id": "A0A8M2BAA1_DANRE", "id": "A0A8M2BAA1-1", "name": "", "aln": "-----MAVNIGKAAQAGLLSQQYPPPLLPKPGKENVRLQKLQKKTAKKKAAAQVLQPSAPFRSSLSPVNEASPDLEHSDHSTPPKTPETPFYISTVHPRFNVRPLYQHVSSPYPHHRGFTFGQTTRFSPQPHVAPGHTTYTASPGIDIHITAPITVLQISQRAEVGSALMTHVITSKTPSPQPNVPRAAKPLFEVPQITNYTAKSVLLQIPYTSTTRSKTPTAELLRGPTPTFEVRRIVTPTSEIRDRTPTREIKKATTPTFEIKRIATPTSEIKKAPTPTSEIKTTPTQTSEIKTTPTQTSEIKKETIPSSEMKRVSTSASGITQNGTETLDAKQGTTSTLEPKGITTPVRVKTPTYDLISIRTPMGRPKTPSDHVSRVRVSVIEISRPNPLLFAVSPVHMEGRRSKTPTSSVTGPRDEIIKVSTQVNGTSHSEIYQNGDIDAKSVEPLKEKLDKALSENLPKLESSKPKNQIQESPNLNGNERPKQETPTTLNIEPTQSHFSSVEYQRPLSKVPPFAGQRPKTPTAPKSKPAYYGLTPAEYAAHGGIKSFSPSFSISTPTVQPSAEATHLPKQVPVVPQPDENVTTPNKNSEKQQVQPPQTDVVKHKITEVSSLLDISNTLGDIPKQPVPELKTKKADVKIPTIVVSVADTPSSEAKAVAVSTVTPRVRTPTYGSPRLSQMTPALPTVKETTKTESKAVVLSDQDVDKPALSKVSEGKVNAKPTKESEKPTEAKMSLLERIKKQKLTSASSEKPPEKVEVKDVVKPLAEPKDQKDIETKDAQPEKVDKVDTKASPQEEIKPAVEKKEKDEASSLPAESLLKVMQKPKGMKSKLSGWSRLKKHMVVDVEEPKFPETEPGSEKDVPATTDQNEKQMQNKPEDKAKLSESQDSKDPPRATKMWDAVLFQMFSTEENIMQQIEASKTEEQKIMEAEQKTPKEIPTFAHRLPVLLYSPRFDARRLREAASRPATKIATVFEMGLIGRKNKDEEPKDFNRTAKGFSG-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : . . : .* : ***. .. *: *. .:. ..: . * .*: .* * * : : * . . : : : .*** *. .* :. ....*:* *. ***: ***::: :. ** ** . . * * * .*:::******::* :* : : .. . : ***.* ***:**:*:*.. *.* . : .**:***** *: ", "identical_positions": 64, "similar_positions": 74, "identity": "6.37%" }, { "cls_id": "homologset.agr.HGNC:3512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V901-1", "uniprot_id": "G3V901_RAT", "id": "G3V901-1", "name": "Exostosin-1", "aln": "MQAKKRYFILLSAGSCLALLFYFGGVQFRASRSHSRREEHSGRNGLHQPSPDHFWPRFPDALRPFFPWDQLENEDSSVHISPRQKRDANSSIYKGKKCRMESCFDFTLCKKNGFKVYVYPQQ------KGEKIAESYQNILAAIEGSRFYTSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTWPDYTED-VGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTGGERGFLKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNALYHVHNGEDVLLLTTCKHGKDWQKHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDKILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRIFKHISRNSLIWNKHPGGLFVLPQYSSYLGDFPYYYANLGLKPPSKFTAVIHAVT-PLVSQSQPVLKLLVAAAKSQYCAQIIVLWNCDKPLPAKHRWPAT---AVPVIVIEGESK---------------VMSSRFLPYDNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDNSKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLVSAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQMRLDPVLFKDQVSILRKKYRDIERL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97464-1", "uniprot_id": "EXT1_MOUSE", "id": "P97464-1", "name": "Exostosin-1", "aln": "MQAKKRYFILLSAGSCLALLFYFGGVQFRASRSHSRREEHSGRNGLHQPSPDHFWPRFPDALRPFFPWDQLENEDSSVHISPRQKRDANSSIYKGKKCRMESCFDFTLCKKNGFKVYVYPQQ------KGEKIAESYQNILAAIEGSRFYTSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTWPDYTED-VGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTGGERGFLKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNALYHVHNGEDVLLLTTCKHGKDWQKHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDKILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRIFKHISRNSLIWNKHPGGLFVLPQYSSYLGDFPYYYANLGLKPPSKFTAVIHAVT-PLVSQSQPVLKLLVAAAKSQYCAQIIVLWNCDKPLPAKHRWPAT---AVPVIVIEGESK---------------VMSSRFLPYDNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDNSKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLVSAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQMRLDPVLFKDQVSILRKKYRDIERL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16394-1", "uniprot_id": "EXT1_HUMAN", "id": "Q16394-1", "name": "Exostosin-1", "aln": "MQAKKRYFILLSAGSCLALLFYFGGLQFRASRSHSRREEHSGRNGLHHPSPDHFWPRFPDALRPFVPWDQLENEDSSVHISPRQKRDANSSIYKGKKCRMESCFDFTLCKKNGFKVYVYPQQ------KGEKIAESYQNILAAIEGSRFYTSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTWPDYTED-VGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTGGERGFLKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNALYHVHNGEDVVLLTTCKHGKDWQKHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDKILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRIFKHISRNSLIWNKHPGGLFVLPQYSSYLGDFPYYYANLGLKPPSKFTAVIHAVT-PLVSQSQPVLKLLVAAAKSQYCAQIIVLWNCDKPLPAKHRWPAT---AVPVVVIEGESK---------------VMSSRFLPYDNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDNSKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLVSAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQMRLDPVLFKDQVSILRKKYRDIERL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5IGR8-1", "uniprot_id": "EXT1A_DANRE", "id": "Q5IGR8-1", "name": "Exostosin-1a", "aln": "MQAKKRYLILFSAGVCLILLFYLQG--------PASRRTPKRGD-----DPHPHWPHFSDPLRAFIPWDQTETEDYNVRASPRHKRDDSTGADK---CRMDSCFDFELCKRNGFKVYVYPQQ------KGEKISESYQNILSSIEGSRFYTSDPGQACLFVLNLDTLDRDQLSPQYVHNLKTKIQNLNLWNNGRNHLIFNLYSGTWPDYTED-LGFDIGQAMLAKASISTESFRPNFDISIPLFSKDHPRTGGERGFLKYNTIPPFRKYMLVFKGKRYLTGIGSDTRNALYHIHNAEDVVLLTTCKHGKDWQKHKDARCDKDNAEYDRYDYKEMLHNSTFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEIIDWRTAAVIGDERLLLQIPSTVRSIHQDRILSLRQQTQFLWEAYFSSVEKIVLTTLEIIQDRVLQHSAHSTLMWNRLPGGLFTLPQYSSYLGDFPFFYALLGIKPHQKFTAVIHAVT-PLVSQSQPIFKLLVAVAKSQFCAQIMVLWNCDKPLPSKHRWPAT---SVPVIVIEGESK---------------VMSSRFLPYENIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDSNKERWGYTSKWTNDYSMVLTGAAFYHRYYNYLYTHYLPGSLKGLVDQLSNCEDILMNFLVSAVTKMPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQTCMNKFASWFGTMPLVHSQMRLDPVLFRDQVSILRKKYRDIERL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5IGR7-1", "uniprot_id": "EXT1B_DANRE", "id": "Q5IGR7-1", "name": "Exostosin-1b", "aln": "MQAKKRYLISLLTGAFLVLLIYLGGGGVPGPAAPGSRSRTHGYN-----RPDQPWPHFSDPLQHFSPWDHSDTEDYNVHISPRQKRDVNSSVYKGKRCRMQSCFDFSLCQRNGFKVYVYPQQ------KGEKISESYQNILSTIEGSRFYTSDPGQACVFVLSLDTLDRDQLSPQYVHNLKTKVQSLALWNNGRNHLIFNLYSGTWPDYTED-LGFDIGQAMLAKASISTENFRPNFDISIPLFSKEHPRTGGDRGYLKYNTIPPFRKYMLVFKGKRYLTGIGSDTRNALYHVHNAEDVVLLTTCKHGKDWQKHKDARCDKDNAEYDKYDYREMLHNSTFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEVIDWNTAAVIGDERLLLQIPSTVRSIHQDKILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRVLQQSSRSSVMWNSHPGGLFSLPQYSSYLGDLPFFYAKLGIKPSPKFTAVIHAVT-PLVSQSQPILKLIVSVARSQYCAQIIVLWNCDKPLPAKQRWPAT---AVPIIVIEGENK---------------VMSSRFQPYESLISDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDNNKERWGYTSKWTNDYSMVLTGAAIYHRYYHFLYTHFLPSSLKSMVDQLANCEDILMNFLVSAVTKLPPVKVTQKKQYKETMMGQSSRASRWADPDHFAQRQTCMNKFASWFGGMPLVHSQMRLDPVLFKDQVSILRKKYREIERL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V730-1", "uniprot_id": "EXT1_DROME", "id": "Q9V730-1", "name": "Exostosin-1", "aln": "MQAKKRYILVFVS-CAFLAYAYFGGYRLKVSPLRPRRAQHESAK--------DGGVQPHEQLPSFLGAHDMQELQLLQSNQSKSLDSSKHLVTRKPDCRMETCFDFTRCYDR-FLVYIYPPEPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLARLPYWNNGRNHIIFNLYSGTWPDYAENSLGFDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPLRAGATGTVQSNNFPANKKYLLAFKGKRYVHGIGSETRNSLFHLHNGRDMVLVTTCRHGKSWRELQDNRCDEDNREYDRYDYETLLQNSTFCLVPRGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYPVRSSLVWNSSPGALLTLPTFADSSRYMPFLLNSMGAEPRHNYTAVIYVQIGAALGPNAALYKLVRTITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYKDRETGR----SPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYRQIELVGS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:: : : : *: * * . : : * * .. : : ..: . . : ***::**** * . * **:** : . : .**:**::*: **:***** **:***.:******.** :**:*: ::: * *******:************:*: :*** *:*:*****:.. .:* .**:***** *:.* .* * :: *.:*. :**:*.******: ****:***:*:*:**..*::*:***:***.*:: :* ***.** **::***. :*:*:**********************.*:**:***.* ***.. *:*. **: .*******:*. :*** ::*::******.*** **.*:****:**:***::*: . :.:::** **.*: ** ::. :*: :* :* ::****:. . :. . .: **: : ::**: :*:*** .*:*** *:***.* .: :: : *..: :*.** **:.: :*********::*.* *:***:***:.***********:****..*: ********* **:******:**:**::**:::*. * *:* :********:*** **: **:****:* **: *: * * ***** ***:*:*.**: ** ***::*::*:**:*::* ** ******:** : ", "identical_positions": 366, "similar_positions": 205, "identity": "47.29%" }, { "cls_id": "homologset.agr.HGNC:35121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFB8-1", "uniprot_id": "D3ZFB8_RAT", "id": "D3ZFB8-1", "name": "", "aln": "MVFRFASFSD--SSPPEPSTQPKRPSVKWDLGS------DYEDVSNETTASGSDFRRQRTASQPDIGLHVQPQIYFLRPRSPIPKLLFSLINTSDANVKKMLPKSHLSRVIIRDNLNAQRIYEMEMKASDKTKRKMSYLYDHLKKKFMTDQLRKMMRWRRDSMSTQQYLDR---KRVC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR34-1", "uniprot_id": "CE052_MOUSE", "id": "Q9CR34-1", "name": "Uncharacterized protein C5orf52 homolog", "aln": "MVLGLASFPESLSSQSETATQPRRPSVKWDLGS------DYRKGTEETTASGSNFRRERLDSQPDLGLHVQPQIYFLRPRSPLPKLLFSLMNTNDANVKKLLPKSHLSRVIIRDNLNAQRICEMEMKASDKTKRKMSYLYDHLKKKFMMDQLRKMIRWRRDSQSTQDYLDK---ERV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGY3-1", "uniprot_id": "CE052_HUMAN", "id": "A6NGY3-1", "name": "Uncharacterized protein C5orf52", "aln": "------------------MTQPTRPSVTCDQGSSTIGGTAAQATTSSSATSGSNYQRDRLGRRPEIGVGGQPQICFPRPRSAQQPVLFSLMNSSEAAMKKTLPKSHLSRVIIHDNRITQRIYEMEVSALEKTKKKISHYYEHLKKKFMTEQLRKLGRWREESVNSNRYLTFGIPPPV-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ****. * ** . :..:::***:::*:* :*::*: **** * ****. :****:*:.:* :** ***********:** :*** ***:.* :***:*:*: *:******* :****: ***.:* .:: ** * ", "identical_positions": 78, "similar_positions": 39, "identity": "43.82%" }, { "cls_id": "homologset.agr.HGNC:35123", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A3KNJ3-1", "uniprot_id": "FXI3A_DANRE", "id": "A3KNJ3-1", "name": "Forkhead box protein I3-A", "aln": "-------------------------------MTSFVPQSLS-----PQFHSMGQESQEFSLYG-DNF--YSAQ---------------HVPSPQQTLPSAYDFGEYAGQ---TSNPYLWFNGP--------------------------GLSPAPCL--TTG-------PQHYGMAKQYVGASGIGGSE-GAFSWFSLPSQEDLMKLVRPPYSYSALIAMAIHGAPNRRLTLSQIYQYVADNFPFYNKSKASWQNSIRHNLSLNDCFMK--------VPRDDSDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDS---LAEEEGKG--YSGSDSALS-----------SPKNP----SDSSERGNSPISTDQAP---------CLNSFLNQMGDVASG-SRE-----ALLPSPLAVPLS--QRSSPTGVYGSYSPNATMPQWETQ---IPQSS-ISSTPYKD--GYSDSMLNPYSSQLYPVLGSSDLLYPREGSEV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T1C0-1", "uniprot_id": "FXI3B_DANRE", "id": "Q7T1C0-1", "name": "Forkhead box protein I3-B", "aln": "-------------------------------MTSYESQGQSPTRCGPQFLSLGQEPPELSLYS-DSY--YPPP---------------SLPSPQRTNPSSYELGDYAAS---SPNPYLWFNSP--------------------------GMNSAPYLGGTPGPAGPSFVPQHYGMQRPYLGPGPPGGPG-GELSWFSMPSQEDLMKLVRPPYSYSALIAMAIHGAPERRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKK--------VPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDS---LPEKSSSGGNESGDSNGRG-----------SPKSQSIDISTSPEKGPSPASTGPSP---------CLSNFLTEMSGVAAG-SLDMEADPLSRPFTLSLPVDGAQRASQTTGFSTFTPSTTVSDWASP---LPPPPPMSSSPSHSTLAYSGPVLSQFNGHFFPGLSSTGILYPREGTEV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3Z120-1", "uniprot_id": "FOXI3_MOUSE", "id": "D3Z120-1", "name": "Forkhead box protein I3", "aln": "----------------------------------------------------------MALYCGDNF-VYSQP--------------AAAPGAPPTSRAPYGLSDYAAPPAAAANPYLWLNGPGVGGP-----ASAASYLGAPPPPP--GAAPGPFLQPPAAPGTFAGAQRGFAQPSASAPASPAGSAAPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADNFPFYQRSKAGWQNSIRHNLSLNDCFKK--------VPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRRRRAEASSNLTVPSGTSKSE-GQSSRLR----VSGKLEGDSPSSILRPSQSPEPPEGTKSTASSPGASTLTSTPCLNTFLSTFNTLNVNSSSSMGNQRTLPGSRRHLG--GTQLPSS-TFPNTSVPDSSPDSMQLS--TVGGSNQLSSYYNPFSGGSSGDQSSPFSSPFYNFSMVNSLIYPRDGSDI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLN2-1", "uniprot_id": "D3ZLN2_RAT", "id": "D3ZLN2-1", "name": "", "aln": "-------------------------------MLSPKRRGQPLSP-KAAAAPHQPSASDMALYCGDNF-VYSQPAA------------AAAPGAPPTSRAPYGLSDYAAPPAAAANPYLWLNGPGVGGP-----ASAAGYLGAPPPPP--GAAPGAFLQPPAAPGTFAGAQRGFTQPSAAAPASPAGSAAPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADNFPFYQRSKAGWQNSIRHNLSLNDCFKK--------VPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRRRRAEASSNLTVPSGTSKSD-GQSSRLR----VSGKLEGDSPSSMLRPSQSPEPPEGTKSTASSPGASTLTSTPCLNTFLSSFNTLSVN-ASSMSTQRTLPGSRRHPG--GTQLPSSTTFPSTSIPDSSLDSVQLS--TVGGGSQLSSYYSPFSGGS-GDQSSPFGSPFYNFSMVNSLIYPRDGSDM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MTJ6-1", "uniprot_id": "FOXI3_HUMAN", "id": "A8MTJ6-1", "name": "Forkhead box protein I3", "aln": "----------------------------------------------------------MALYCGDNFGVYSQPGLPPP------AATAAAPGAPPAARAPYGLADYAAPPAAAANPYLWLNGPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAAPASPAAPAGPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQRSKAGWQNSIRHNLSLNDCFKK--------VPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEASNGSTVAAGTSKSEEGLSSGLGSG--VGGKPEEESPSTLLRPSHSPEPPEGTKSTASSPGGPMLTSTPCLNTFFSSLSSLSVS--SSVSTQRALPGSR-HLGIQGAQLPSSGVFSPTSISEASADTLQLSNSTSNSTGQRSSYYSPFPASTSGGQSSPFSSPFHNFSMVNSLIYPREGSEV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W5X5-1", "uniprot_id": "Q9W5X5_DROME", "id": "Q9W5X5-1", "name": "", "aln": "------------------------------------------------------------------------------------------MDTTPIFQSSFSIRSLLSVDKKEESPISKHNSG--------------------------------------------------SSFSSCSSSSSNSSSD-------SMAAKSN----AKPAFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVR--------VPRALDDPGRGHYWALDPYAEDLSIGETTGRLRRS----------------------------------------------NWQQNTGARPKVTGHP---------------YQRMPYYGHG------------------HGNGPYIKAHSAYFPIMDHQHHAAMVQHYQAMMHRYQMMPHPHHHQHQHQHQHPHSHFIQQSKPLHIQEPYHHTRYHLHQE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFG-----RNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAG----------KLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :. . : :. : : *: : : *. : ::.. .. :. : .: . : : : .. . .*: :: .: : : . . : . : . . .. ", "identical_positions": 3, "similar_positions": 51, "identity": "0.6%" }, { "cls_id": "homologset.agr.HGNC:35126", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY30-1", "uniprot_id": "D3ZY30_RAT", "id": "D3ZY30-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGTPGLGLRGLKRGEDSVGDLGHSCPEAGRNFGVLRR-----SLAEEEEVAGRKRERPARSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAP--RWPCGHLECH--GQAAHGSSAGDSGFSVPRSVLSPAAPSLARRDTAS-----PLVPPAPRCASCSPNAHLGRPRMMAEVP------SLAQASGGSWR--RCPG---AAPVGSIQWRWG-----SGLGYQHS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RJB0-1", "uniprot_id": "BHA09_MOUSE", "id": "Q5RJB0-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGTPGLGLGGLNRAEDFVEDLGRSCSEAGRNFGVLRRS----SLDEAEEAAGRKRERPTRSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAP--RWPCGHLECH--GQAAQGSSTGNSSFSVPRSAPSPIAPSLTRRDIAS-----PLVPPTPRCASCSPHSHLGRPRVMAEVP------NLAQTSGGNWR--QCPG---APPVRPVSWRWG-----SGLGYQHS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU4-1", "uniprot_id": "BHA09_HUMAN", "id": "Q7RTU4-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAP--RGPCGHLECH--GPAARG-DTGDTGASPP----PPAGPSLARPDAAR-----PSVPSAPRCASCPPHAPLARPSAVAEGP------GLAQASGGSWR--RCPG---ASSAGPPPWPRGYLRSAPGMGHPRS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNX5-1", "uniprot_id": "BHA09_DANRE", "id": "A3KNX5-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "-MTPVSVCRFSMASRGSFTGSEFSEEEPDGSLQESELDSSDGLGGLNEPEERLIKKRSRPVRSKARRVAANVRERKRILDYNQAFNALRVALHHDLSGKRLSKIATLQRAINRISALSVFLTNNPPVGVAKPCGHLECQPGGLWAEAEPSMQNFLTWHQPLNQHLQTSIHRLSSEQHVFTGPACPPSPHYPCFSPDTQLYPAASVPSPPRYGRIGDVGAYQQGVWGGNHADGYGESLQTLPLPWHMG---YLQDAGLQHCPNTLCYTQCKTVRAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . .. ::. .: . : . * . * ** ::* **.******:**************:****** **:***.**********:***:**:***:.* .*. *******: * *.. : :. : .*: * . * *.:*: .. .*.: * . :.. * .:. . * * :. * : . . * * . * :. ", "identical_positions": 81, "similar_positions": 64, "identity": "29.45%" }, { "cls_id": "homologset.agr.HGNC:3513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAH7-1", "uniprot_id": "A0A0G2KAH7_RAT", "id": "A0A0G2KAH7-1", "name": "Exostosin-2", "aln": "MRSARRVRRGELEAGAAFPGWLWLTWCWRRPPVTARSDTAVARAPRPKPVAERGAEREAAGSEVCEDEDICVIMCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRS----IREVPVVRLTADSPIPER--GDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSA-ISREYNELLTAISDSDYYTDDISRACLFVPSIDVLNQNPLRIKETAQALAQLPRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEVALPEKAPGSRRYFLLSSQMAIHPEYREELEALQAKHRESVLVLDKCTNLSEGVLSIRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVIPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFRSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70428-1", "uniprot_id": "EXT2_MOUSE", "id": "P70428-1", "name": "Exostosin-2", "aln": "-------------------------------------------------------------------------MCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRS----IREVPVVRLPTDSPIPER--GDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSA-ISREYNELLTAISDSDYYTDDINRACLFVPSIDVLNQNPLRIKETAQALAQLSRWDRGTNHLLFNMLPGAPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEMALPEKAPGPRRYFLLSSQMAIHPEYREELEALQAKHQESVLVLDKCTNLSEGVLSVRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDTHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93063-1", "uniprot_id": "EXT2_HUMAN", "id": "Q93063-1", "name": "Exostosin-2", "aln": "-------------------------------------------------------------------------MCASVKYNIRGPALIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRS----IRDVPVVRLPADSPIPER--GDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNT-ISREYNELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TX90-1", "uniprot_id": "A0AB32TX90_DANRE", "id": "A0AB32TX90-1", "name": "Exostosin-2", "aln": "---------------------------------------MVDKIPLLKWFCLDR-----------------LIMCASGKYGSRGPALIPRMKTKHRIYYITLFSVVLLGLIATGMFQFWPHSIESSAEWSLDRRS----VHDAPLVRIPVNSPIPGR--GDLSCRMHTCFDVYRCGYNPKNKIKVYIYPLQRFVDEVGVPISSTGLSREYNDLLSAISDSDFYTDDVSRACLFVPSIDVLNQNSLRIRETAQALAMLPRWDKGMNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERQPGPRRYFILSSQTAIHREYRVELERLKDENGEALLLLDKCSNLSQGLTSVRKRCYKGQVYDYPQILQESSFCVVLRGARLGQATLSDVLQAGCVPVIMADSYILPFSEVLDWKRASVVIPEEKLPEMYTILKSIPHRQVEEMQRQARWFWEAYFSSMKAIGMTTLQIINDRIYPYAAHTYEEWNNPPVVKWSSVNSPLFLPLIPPRSPGFTAVVLTYDRIESLFRVITEISKVPSLAKLLVVWNNQNKSPPEESLWPKVAVPLKVVRTKENKLSNRFFPFDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMGKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANITGKAPIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y169-1", "uniprot_id": "EXT2_DROME", "id": "Q9Y169-1", "name": "Exostosin-2", "aln": "-----------------------------------------------------------------------MTKIKNLLSFVTQSRAISHTNPREHILNCLTYGLLVIVALCAG-FLLWDLSSSPRDGFFHGKRDSHTLILDLEHIQELAVNPEAEQRARNVNCTFWDCLNIYKCEHD---RLKVYIYPLQEFVDEQSDKTATT-LSSEYFQILEAVLKSRYYTSNPNEACLFLPSLDLLNQNVFDKHLAGAALASLDFWDRGANHIIFNMLPGGAPSYNTVLDVNTDNAIIFGGGFDSWSYRPGFDVAIPVWSPR--LVRQHAHATAQRKFLLVVAQLNILPRFVRTLRELSLAHSEQLLLLGACENLDLTMRCP--LSQHHKSLEYPRLLSRGKFCLLGRSLRMGQPDLVEIMSQHCIPVIAVDNYVLPFEDVIDWSLASVRIRENELHSVMQKLKAISSVKIVEMQKQVQWLFSKYFKDLKTVTLTALEVLESRIFPLRARSSRQWNTIDTNARSTFN-PLFLPSLAPKSQGFTAVILTYDRVESLFLLIQKLAVVPSLQSILVIWNNQKKSPPHLSTFPSISKPLKIRQTKENKLSNRFYPYPEIETEAILTIDDDIIMLTTDELDFGYEVWREFPDHIVGFPSRIHVWENVTMRWHYESEWTNQISMVLTGAAFHHKYWSHMYTHAMPGDIKDWVDEHMNCEDIAMNFLVANITNNPPIKVTPRKKFKCPECTNTEMLSADLNHMRERSACIDRFSKIYGRMPLRTVEFRADPVLFRDNFPDKLKRYNDIGSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *.: :.:.:* :.:::: :.:* * :* * .. :*. : : :: . .* . : ::.* : *:::*:* .: ::*****.*:.:**: . :.: :* ** ::* *: .* :**.: ..****:**:*:**** : : :. *:* * **:* **::******..*.***.*** *.*:: ****.:*:** *:**:***:** : : .. *::::: :* : .: *. *. : * :*:*. * **. : . . : : :**::*....** : *. *:**. * :::. *:**: .*.*:***.:*:**. *** : *::: .: *: *. :: ***:*.:*::. ** .:*:: :::*::::.**:* * : .:** . .:.. ***** :.*:* ****::*****:**** :* ::: **** .:**:****:*.**. * :*.: ***: :* ********:*: ******:*:*********:***:***********::**:*.*:*:*:: :*:*******::*********:***:.::**: ******:*** ***************:*.:. *************** : ** * .** *** **::*:.::* ***:.**.******::*:**:*** : :****", "identical_positions": 309, "similar_positions": 239, "identity": "38.72%" }, { "cls_id": "homologset.agr.HGNC:3515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLU1-1", "uniprot_id": "D3ZLU1_RAT", "id": "D3ZLU1-1", "name": "Exostosin-like 1", "aln": "-MLWRR-KSFWLALSAFWLLLILLGVFP-LRLAVSPRPLPGRSQGWPRWLDATFLQSFSQPETNPEEDVQQLPRVS----------RGSSCTWGACFDTSKCRGK-VLKIFVHSAAG--------PTTEAQRRILDSLEGSRYYALSPAEACLLLF---------LPSQDRRGACGPLP--PNWNGGRNHLVLSLYP------APCTR---LGQAMVAEASPSLDIFRPGFDVALPYLPEAHPLKGGAPGSLQRHGPQPG-ATLVAVAEERGRWRITTTHA---------------SACPW--------DRNCEQDPGPQQTYP-GEILPNVTFCLIPGHR-SATSCFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALREMLPSRVLALRQQTQFLWTAYFSSVEKVVHTTLEIIQDRIWGASAHPSLMWNSPPGALLALPTFSTSLQDFPFYHLQLGSSPGSSFSAVIWVGV-----SEESPPKLIQEVAGSRHCAQILILWNSEKPPP--DRWPKTA-VPLTVI------------------EGHRKVSDRFFLYSNISTNVILSLDAQSTLSTSEVDFAFVVWQSFPERMVGFVTWSHFWDEARQGWGYSAEMANEFSMVLTTAAFYHRYYHTLFTHSLPKALRSIADETPTCVDILMNFLVATVTKLPPIKVPYSRQHQEAAP--MASEGPRPVPEPQALDQDCINRLAAGLGHMPLVSSRVRLDPVLFKDPVSVQRKKYRSLEKP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKV7-1", "uniprot_id": "EXTL1_MOUSE", "id": "Q9JKV7-1", "name": "Exostosin-like 1", "aln": "-MLWRR-KSFWLALSAFWLLLVLLGVFP-LRLAVLPGPLPGRSQGWPRWLDAAFLQSFSQSETNPE-DVAQLPRVS----------RGSSCTWGACFDTSKCRGK-VLKIFVHSPAG--------PTSEAQRRILDSLEGSRYSALSPADACLLLF---------LPSQDRRGACGPLP--PNWNGGRNHLVLSLYP------APCTR---LGQAMVAEASPSSDIFRPGFDLALPYLPEAHPLRGGAPGKLQQHSPQPG-ATLLAVAEEKGRWRITSTHA---------------SACLW--------DRHCEQDPGPQQTYP-GETLPNATFCLIPGHR-SATSCFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIIADERLPLQVLAALREMLPSRVLALRQQTQFLWTAYFSSVEKVIHTTLEIIQDRIWGASGHPSLMWNSPPGALLALPTFSTSLQDFPFYHLQLGSGPGSSFSAVIWVGA-----SGESLLKLIQEVAGSRHCAQILILWNSEKLPP--DRWPETA-VPLTVI------------------KGHRKVSNRFFPYSNISTNVILSLDAQSTLSTSEVDFAFVVWQSFPERMVGFLSGSHFWDEAQGGWGYRTGMTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTIADETPTCVDVLMNFLVATVTKLPPIKVPYGRQHPEAVP--MDSGDPRPVPEPQPLDQDCINRLAAGFGHMPLVSSQVRLDPVLFKDPVSVQRKKYRSLEKP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92935-1", "uniprot_id": "EXTL1_HUMAN", "id": "Q92935-1", "name": "Exostosin-like 1", "aln": "MQSWRRRKSLWLALSASWLLLVLLGGFSLLRLALPPRPRPGASQGWPRWLDAELLQSFSQPGELPE-DAVSPPQAP----------HGGSCNWESCFDTSKCRGD-GLKVFVYPAVG--------TISETHRRILASIEGSRFYTFSPAGACLLLL---------LSLDAQTGECSSMP--LQWNRGRNHLVLRLHP------APCPRTFQLGQAMVAEASPTVDSFRPGFDVALPFLPEAHPLRGGAPGQLRQHSPQPG-VALLALEEERGGWRTADTGS---------------SACPW--------DGRCEQDPGPGQTQR-QETLPNATFCLISGHRPEAASRFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALQEMSPARVLALRQQTQFLWDAYFSSVEKVIHTTLEVIQDRIFGTSAHPSLLWNSPPGALLALSTFSTSPQDFPFYYLQQGSRPEGRFSALIWVGP-----PGQPPLKLIQAVAGSQHCAQILVLWSNERPLP--SRWPETA-VPLTVI------------------DGHRKVSDRFYPYSTIRTDAILSLDARSSLSTSEVDFAFLVWQSFPERMVGFLTSSHFWDEAHGGWGYTAERTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTLADEAPTCVDVLMNFIVAAVTKLPPIKVPYGKQRQEAAP--LAPGGPGPRPKPPAPAPDCINQIAAAFGHMPLLSSRLRLDPVLFKDPVSVQRKKYRSLEKP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V730-1", "uniprot_id": "EXT1_DROME", "id": "Q9V730-1", "name": "Exostosin-1", "aln": "-MQAKKRYILV-FVSCAFLAYAYFGGYRLKVSPLRPRRAQHESAKDGGVQPHEQLPSFLGAHDMQELQLLQSNQSKSLDSSKHLVTRKPDCRMETCFDFTRCYDR--FLVYIYPPEPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLARLPYWNNGRNHIIFNLYSGTWPDYAENSLGFDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPLRAGATGTVQSNNFPANKKYLLAFKGKRYVHGIGSETRNSLFHLHNGRDMVLVTTCRHGKSWRELQDNRCDEDNREYDRYDYETLLQNSTFCLVPRGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYPVRSSLVWNSSPGALLTLPTFADSSRYMPFLLNSMGAEPRHNYTAVIYVQIGAALGPNAALYKLVRTITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYKDRE----TGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYRQIELVGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5IGR6-1", "uniprot_id": "EXT1C_DANRE", "id": "Q5IGR6-1", "name": "Exostosin-1c", "aln": "-MQARKKYVLLGLCTCCWILLYYWAGLQERLLGLITHRRGEVPRPWPDWLDRALLPNFAEQLDLQNGGGP-GDSPRQRKQAWSSIYKDSRCRMDTCFDFGRCQTQSGFRVYIYPPE------KGERVSEGYRKILTSVSESRYYTSDPREACLFVLGIDTLDRDQLSQQFVPNVDERIRGYPLWNDGRNHVIFNLYSGTWPNYTED-LGFNVGQAILAKASLNTEHFRPGFDISIPLFSKEHPQKGGKRGWLVRNSVPPRRKYLLMFKGKRYLTGIGSDTRNALHHIHNGKDIVSLTTCRHGKDWEKHKDARCDHDNQEYERFDYQELLHNSTFCLVPRGRRLGSFRFLESLQAACIPVLLSNGWELPFSDVIQWNQAVVEGDERLLLQVPSTVRAVGIDRVLALRQQTQTLWDAYFSSVDKIVLTTLEIIKDRVYSHISRNKLMWNALPGGLLVLPEFSTHLAHYPFYYLHLGISPGLEFTAVIHATS-PLVSQSQPIMKLLQVVSKSKYCSQIIILWNSEKSPPQRSKWPPMP-VPLTVT------------------DGRRKTSSRFLPHAAIETEAVLSLDEDTVLLTSEINFAFHVWRSFPDRIVGYPPRSHFWDPVKKAWGYTSKWTNEYSIILTGAAFYHRYYHHLFSHYLPSSLRALVDHSCNCEDILMNFLVSSVAHLPPVKVAQRKQYKEMPSLQGTKMAPWANPEHFTQRQECVNTFSSWFGYMPLEHSQFRLDPVLFKDHVSVLRKRYKDLERV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :. :: . : . . * .* : : * :*** :* : ::::.. : ::** ::. **: : .* ***::: *. : . : ** ****::: *:. : *:*::*:** :* ***:::* : : .* :.* * : :. . *: . :: ::* * .*:.* : * * ****:. * .: **::***.******* * ***.. *:*.:*.: .**** *** :: : *::******* ** **.*::*:: **:*:*::*: . : .*:**: **.**.*. *: ** * * ::*:* . . **:: :: *:. :*::** :: * .:** . :** * .*: . *.** : * *:.:**** : * *.*::**: **:.**:*:**: . :**** : .*** : :* :*::** ********: *::: *. * .:.: .* *:***::*: *:: **:**. : : * *. .*:* ::: :*:*** *..*:**:*::* ** **:*:.:* ", "identical_positions": 195, "similar_positions": 196, "identity": "25.39%" }, { "cls_id": "homologset.agr.HGNC:35153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXV7-1", "uniprot_id": "F187A_RAT", "id": "Q6AXV7-1", "name": "Ig-like V-type domain-containing protein FAM187A", "aln": "MRLAPTTVLLWAWGSLQAFEIVEKENIFQRTPCPAFLVFDNTAYLADMSFELPCHCKPEDVSAVVWYYQKYLGSSHTTVLTDFDGRLLTEAAHVRVGSSMLARFSIRMFSLLVFRAQPEDSGLYFCGTRNGDYFYAYDVDIQSHKGMVASFRDKGQEPLPDEYYGSLHVFTTFWEWTPCDRCGVRGEQWRFGLCYLQNPNLSPRYIKTLPDVVSCGSRAVPWKLHLKTKYHTPELLIQSCLVSCKK-NKMGEGILAIYNYVSKLGGRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDSQPLYRTQYLKGVNRSMRVFIDHGNHLHIRFTQLSDRGIYYCWRQGLKIAGFRLGVTSRGRYPASLSDPETRTAVELTLIGYLLIAVVFVTIHLCRCCCQS-RCCPNFSAQTLLQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3R5-1", "uniprot_id": "F187A_MOUSE", "id": "Q9D3R5-1", "name": "Ig-like V-type domain-containing protein FAM187A", "aln": "MSLAHTTVLLWAWGSLQAFEIVEKESVFQRTPCPAFLVFDNAAYLADMSFELPCHCKPEDVSAVVWYYQKHLGSKRTTVLTDFDGRLLTEAAHVRVGSSMLVRFSIRMFSLLVFRAQPEDTGLYFCGTREGDYFYAYDVDIQSNKEIVASFKDMAQEPLPDEYYGALHVFTTFWEWTPCDRCGVRGEQWRFGLCYLQYPDLSPRYIKTRSAVVSCGSGAVPWKLHLQTKYHTPELQFQSCLVSCQKRNKTRKGVLAIYSYVSKLGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDNQPLYRAQYLKGVNRSMRVFIDHGNHLHIRFTQLSDRGIYYCWLQGLKIAGFRLGVITRGRYPASLSDPETRTAIELTLMGYLLITIFFITIHLCRCCCQS-RCCPNFSAQTLL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFU0-1", "uniprot_id": "F187A_HUMAN", "id": "A6NFU0-1", "name": "Ig-like V-type domain-containing protein FAM187A", "aln": "MHLALTTVLLWAWG-LQAFEIVEKENIFQRTPCPAFLMFENAAYLADMSFELPCHCKPEEVPAVVWFYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDMLTRFSIRMFSLLVFRAQSEDSGLYFCGTRKGDYFYAYDVDIQNSEGMVATFQDKGQEPFADEYYGHLHVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDLSPRYLKAVPDVVSCGSRAVPRKLRTKARDHTPEVLVRSCLVPCEKTKTIREGVLAIINYVSKVGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDRQHLYRTQYLKGVNRSMRVFIDHGNQLHIRFTQLDDRGIYYCWRQGVLVAGFRLGVTSHGHYPASFSDPETRSAVELTLIGYLLITAVFVTIHFCRCCCYLFHCCPSFSP------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** ********* **********.:**********:*:*:*****************:*.****:***:***.:*.********:*****:*****.**.***************.**:********:************. : :**:*:* .***:.***** ************************:****** *:*****:*: . ****** *** **: ::: ****: .:****.*:* :. :*:*** .****:*.************************************** * ***:******************:********.******** **: :******* ::*:****:******:*:****:*****: .*:***:***** :***.**. ", "identical_positions": 319, "similar_positions": 67, "identity": "75.95%" }, { "cls_id": "homologset.agr.HGNC:35154", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KXQ8-1", "uniprot_id": "A0ABK0KXQ8_RAT", "id": "A0ABK0KXQ8-1", "name": "MAGE domain-containing protein", "aln": "MPRGHKSKARAREKRRQVQDEAQGLKNAQAKAAEKGESSSCS--------------------DHDSGDAVASTSTAVG--PYRRSRKSTKGPRE-----------ESTSCILMQYLLCKYKMKQPANKGEMLKVINKRFKEQLPDILKKASERIQLVFGLEVKEIKPNGGYYTLVSKLDPNVGGTLTTSLPFPQNGLLMPLLGVIFLNGNRASEADIWEFLNILGIHDGKVHIIFG-EPRKLITRDLVKEKYLVY--QKEANSNPPSFEFLWGPRAYAETTKMKVLEFLAKVNETVPQAFPTHYQEALRDQEERAQAEAVGSPGTSAKDEAESKVRPVNSSCHTEISQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NCF6-1", "uniprot_id": "MA13P_HUMAN", "id": "A6NCF6-1", "name": "Putative MAGE domain-containing protein MAGEA13P", "aln": "MPHSQKSRHCELEQGLQAPKEAQGLVGVQVAEAEKVNTTASSSPSTLIQGTLEKVSASGTPGTPQSSQRVCSPCTTIKATPWNQSDESSRSQEKKDPGASQALMLEKKVDELVKFLSVKYTTKQPITEAEMLKGVIKEHKDHFPPIFMQAHECMEIVFGTDMKEVDPISHSCVLLKSLDLTYDRRLSDDQGMPKTGLLILTFGVILMEANCASEEKIWEVLNIIRVYAGWKDFIYG-EPRKLITRDLVQEKYLEC--CQVSNSDPPRYKFPWGPRAHAETTKMKVLEFFSRVSGSDASSFPLLYEEALRDEKEKAQAIIATMGGTTLMASAHSWAKSSSFSCPE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "MASTSRAARSQNAIPSQEAQQPVDVVDAKVR-------------------------------------------------------------------------------AILNYILDHTAQKIPIKDKDLIAVAGD--KSELKKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVASIHELTPAQ-RPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: * .:. .: ..:. ::::: : * * .. ::: . *..: : . : : .** :. :.. . *: *: ** : *::..* .: .:: .*::: :: . . :* : ** * . :*:::** : : : . * ***** ** * ::::* ::: .. * . * .. : . ", "identical_positions": 33, "similar_positions": 83, "identity": "9.48%" }, { "cls_id": "homologset.agr.HGNC:35155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5XVC9-1", "uniprot_id": "A0A8I5XVC9_RAT", "id": "A0A8I5XVC9-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAWHKVTTSGKPLESTVPESNTVWEPIRTSPASRSFQESTLGNALEKTAVVPVQIQLT-SVTLSPEKNAALPIDDSSVSGKTSLICTQEVEKVNEAFDFLLAFFILACILIIFLIYKVIQFKQKLKALEDSVENRLEYYSFYQSARYNVAASVCHTSPDSLESPGLQQIGLDKQIVPENGAQVILFEHSAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z2Q7-1", "uniprot_id": "LRR70_HUMAN", "id": "Q7Z2Q7-1", "name": "Leucine-rich repeat-containing protein 70", "aln": "MCGLQFSLPCLRLFLVVTCYLLLLLHKEILGCSSVCQLCTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLGLRDWLASSAITLNIYCQNPPSMRGRALRYINITNCVTSSINVSRAWAVVKSPHIHHKTTALMMAWHKVTTNGSPLENTETENITFWERIPTSPAGRFFQENAFGNPLETTAVLPVQIQLTTSVTLNLEKNSALPNDAASMSGKTSLICTQEVEKLNEAFDILLAFFILACVLIIFLIYKVVQFKQKLKASENSRENRLEYYSFYQSARYNVTASICNTSPNSLESPGLEQIRLHKQIVPENEAQVILFEHSAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********.*.***.* .*. *.** * ****.* ***.::**.**.***:******* ****. ***:*** * :*:**************:*****:*********:*********:******** *:* *****************:**:*:***:*******:** *.******* ***********", "identical_positions": 151, "similar_positions": 28, "identity": "24.28%" }, { "cls_id": "homologset.agr.HGNC:35158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR58-1", "uniprot_id": "D3ZR58_RAT", "id": "D3ZR58-1", "name": "", "aln": "MTDEWTLKTKAMDIKTASTDLSKETCPADNEQCVKLEKTAIKIQSWWRGNVVRRALLDAALGAWAIQCWWRSMQTKIVEQKRRLALRLYTCQEWAVVKVQAYVRMWQARRRFLQARQAACTIQAHWRWYASQSQAMIHGRYEVEASRLELDIEILMT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A571BFV9-1", "uniprot_id": "A0A571BFV9_MOUSE", "id": "A0A571BFV9-1", "name": "", "aln": "-----------MDIKTVNTDLSKETCPVDNEQSVKLEKTAIKIQSWWRGNMVRRTLLDAALGAWAIQCWWRSVQTKIVEQKRRLALKLYTCQEWAVVKVQAYVRMWQARRRFLQARQAACIIQTHWRWHASQSQGMIHSRYEVKASRLELDIEILVT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MYZ5-1", "uniprot_id": "IQCF6_HUMAN", "id": "A8MYZ5-1", "name": "IQ domain-containing protein F6", "aln": "--------------------------------------------------MVRRTLLQAALRAWVIQCWWRSMQAKMLEQRRRLALRLYTCQEWAVVKVQAQVRMWQARRRFLQARQAACIIQSHWRWHASQTRGLIRGHYEVRASRLELDIEILMT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:**:*** **.*******:*:*::**:*****:************** ****************** **:****:***::.:*:.:***.***********:*", "identical_positions": 83, "similar_positions": 21, "identity": "52.87%" }, { "cls_id": "homologset.agr.HGNC:35159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE78-1", "uniprot_id": "D3ZE78_RAT", "id": "D3ZE78-1", "name": "", "aln": "MGPEETTALTEKSAAVRIQAWWRGTLLRRSLLHAALNAWIIQCWWRKTMMTMQGKKRRMALELYVRKTWAIVKLQSCFRMWHIRQRYCRLLNAVRIIQVYWRWHSCHTRGFIRGNYEIKENRLNIQLEISLGSQACKVEQCITLPIKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAL7-1", "uniprot_id": "IQCF5_MOUSE", "id": "Q9DAL7-1", "name": "IQ domain-containing protein F5", "aln": "MGPEKSTAMTETSAAVRIQAWWRGTLLRRTLLHAALSAWIIQCWWRKIMIMLQGKKRRMALELYARKTWAIVKLQSWFRMWHIRHRYCRLLNAVRIIQVYWRWHSCHTRGFIQGNYEIKENRLNIQLEISLGSQACKVEQCITLPIKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MTL0-1", "uniprot_id": "IQCF5_HUMAN", "id": "A8MTL0-1", "name": "IQ domain-containing protein F5", "aln": "MGPEEKTIMTERSAAVFIQAWWRGMLVRRTLLHAALRAWIIQCWWRQVLEKLLAKRRRMVLEFYVQQEWAAVRLQSWVRMWCVRQRYCRLLNAVRIIQVYWRWHSCHSRVFIEGHYELKENQLNIQLEISLGLQACKVQQCIPLPLKE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:.* :** **** ******* *:**:****** *********: : : .*:***.**:*.:: ** *:*** .*** :*:**********************:* **.*:**:***:********** *****:***.**:**", "identical_positions": 106, "similar_positions": 27, "identity": "71.62%" }, { "cls_id": "homologset.agr.HGNC:3516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES89-1", "uniprot_id": "EXTL2_MOUSE", "id": "Q9ES89-1", "name": "Exostosin-like 2", "aln": "MMRGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETN-GYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F8T0-1", "uniprot_id": "F7F8T0_RAT", "id": "F7F8T0-1", "name": "Exostosin-like 2", "aln": "TMRGCHICKLPGRVMGIRVLRFSLVIILVLLLVAGALTNLLPNIKEDKMLTVRREIKSQSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPNLHKVIVVWNNVGEKGPEELWNSLGPHPIPVLFKPQTANRMRNRLQVFPEVETNAVLMVDDDVLISAQDLVFAFSIWQQFPDQIVGFVPRKHVSTSSGIYSYGGFELQTPGLGNGDQYSMVLIGASFFHSKYLDLFQKQPAAVHTLIDETQNCDDIAMNFIVSKHTGKSSGIFVKPINIINLEKETN-GYSGMWHRAEHFLQRSYCLNKLVNIFSGMPLKYSNIMISQFGFPYANHKSKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBQ6-1", "uniprot_id": "EXTL2_HUMAN", "id": "Q9UBQ6-1", "name": "Exostosin-like 2", "aln": "-MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGKSTMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMISQFGFPYANYKRKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *****************:***:************ ***.:****** :****** .**::*****************:*********.**********:***.*:*************:** ****:**********:***********.***: *******:********:******************.**:*:** ****************:****:***:******:***:***********::::* **.*******:*: ******* *********** ******:******:..***:***************:* *:", "identical_positions": 276, "similar_positions": 42, "identity": "83.38%" }, { "cls_id": "homologset.agr.HGNC:35164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CD96-1", "uniprot_id": "OCC1_RAT", "id": "P0CD96-1", "name": "Overexpressed in colon carcinoma 1 protein homolog", "aln": "MGCGNSTATSAAAGRGKPGAVKDATEDSITEDDKRRNYGGVYVGLPSEAVNIASSQAKTVQKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C913-1", "uniprot_id": "OCC1_MOUSE", "id": "P0C913-1", "name": "Overexpressed in colon carcinoma 1 protein homolog", "aln": "MGCGNSTATSAAAGRGPTGAVKDTTEDSITEDDKRRNYGGVYVGLPSEAVNMASSQTKTVQKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAD7-1", "uniprot_id": "OCC1_HUMAN", "id": "Q8TAD7-1", "name": "Overexpressed in colon carcinoma 1 protein", "aln": "MGCGNSTATSAGAGQGPAGAAKDVTEESVTEDDKRRNYGGVYVGLPSEAVNMVSSQTKTVRKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DGJ2-1", "uniprot_id": "OCC1_DANRE", "id": "B3DGJ2-1", "name": "Overexpressed in colon carcinoma 1 protein homolog", "aln": "MGCGNSTAASTTPG--PAESAKDVQDDSSMDEEKRRNYGGVYVGIPADLTNETAGQTASTHKE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:*: .* . :.**. ::* :::***********:*:: .* .:.*: :.:*.", "identical_positions": 28, "similar_positions": 24, "identity": "44.44%" }, { "cls_id": "homologset.agr.HGNC:35165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DMQ5-1", "uniprot_id": "INAM2_HUMAN", "id": "P0DMQ5-1", "name": "Putative transmembrane protein INAFM2", "aln": "MKERDAAP-AERGKPATYTGDKKAKMAAKTNKKWVRLATVFAYVLSVSLAAIVLAVYYSLIWQPVGAG-------------------------------------------------------------------------------------------------TSGGAAGPPPGGSNATGPSGTSGAAAAGPNT-------------------------------TGSSRREAPR-----DVPPLQAARPAPPEPPADSPPAG-------------------------------------PLERP-RGPDEDEEETAAAPGSR-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1L1STD6-1", "uniprot_id": "A0A1L1STD6_MOUSE", "id": "A0A1L1STD6-1", "name": "", "aln": "MKERDAAP-AERGKPATYTGDKKAKMAAKTNKKWVRLATVFAYVLSVSLAAIVLAVYYSLIWQPVGAG-------------------------------------------------------------------------------------------------TSGGAVGPPPSGSNTTGPSGTSG-VAAGPNT-------------------------------TGSSRREAPR-----DAPPLQAARPAPPEPAADSPLAG-------------------------------------PLERP-RGLDEDEEEAAEEPRSR-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LRF7-1", "uniprot_id": "A0ABK0LRF7_RAT", "id": "A0ABK0LRF7-1", "name": "", "aln": "MKERDAAP-AERGKPATYTGDKKAKMAAKTNKKWVRLATVFAYVLSVSLAAIVLAVYYSLIWQPVGATRRA---------------------------------------------------------------------------------------------PAAGGEAGAPGACCRQPPGRATPAAAGAGRRR-------------------------------RGSGRR-VP------ESLNLSVLGTVGNHRPP-TPQAG-------------------------------------LCSRTGSGARRSDPNASVRPHTPQR---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1NAX0-1", "uniprot_id": "A0A8M1NAX0_DANRE", "id": "A0A8M1NAX0-1", "name": "", "aln": "MRERDFMPNMERGKPATYTGDKKAKMAAKTNKKWVRLATVFAYVLSVSLAAIILAIYYSLIWKPTSASVSGRSDVLMTTTVMAINTSNISVSD---------------------------------------VSTKVNNTSLVSPKSTQTTYDLSTSQMHWGDKKGHEGLIDIPTTKMKKTDQAGTSASTHIQRKSGLFSTAEVSHVLKTSVLVAGESSEALLARGATSSSKQTVYGSSGYDASKNWGLVSPTTDQASWTSYSAGPD-----------------------------------VSSLTERGLDLMEGSSALQEELVTKDTENPIGV-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUS1-1", "uniprot_id": "A8JUS1_DROME", "id": "A8JUS1-1", "name": "", "aln": "MNSKHSSLEEKVKLPPTETISR-CYQPQQSNRKVIRILTVAVYVLCVSLAAIMLSLYYIFIWDPTIRPFVTKATHCDKIVIPEKIAIRLLNSSEVTAEQFYKHILEQYRILSHMQQQRQQLLQRQHLQLQQLEANNRFQEVFATATIIQAHPHPHPHPREPPKKPLLGPYSPQPGNISHAMGGDQLDAETEQGHMPLILDTSPPVEVTGMGHLKRKTHRGHYKHHRARAGGQKKLSIANSMASSTPSTTAGGDASMATAATLPHGYMDAPLNPAAGTIVQAPQLQLYTSMPIPLILSPSDEKRPSHHAHGHVHGERRNGAQSGGRRRTTTASVSGYEAQTYLNPFLTGELIFEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..:. : *.* * .: . . ::*:* :*: ** .***.******:*::** :**.*. * . . . ...:: . : * . * : . ", "identical_positions": 27, "similar_positions": 36, "identity": "7.63%" }, { "cls_id": "homologset.agr.HGNC:3518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6F4-1", "uniprot_id": "A0A0G2K6F4_RAT", "id": "A0A0G2K6F4-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GVGNGGQTCMLR---------------WSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGN--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--VTRGCRLHNCFDYSRCPLTSGFPVFVYDSDQFAF---GSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGE-IQEPAVLQ-----------------------PADLEKQLHSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGRAMVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPSLLISSGCATRLFEALEVGAVPVVLG-EQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRSWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNK-------------------------VVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVL6-1", "uniprot_id": "EXTL3_MOUSE", "id": "Q9WVL6-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GVGNGGQTCMLR---------------WSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGS--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--VTRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFAF---GSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGE-MQEPTVLR-----------------------PADLEKQLFSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGR-HVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPHLLISSGCATRLFEALEVGAVPVVLG-EQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRGWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43909-1", "uniprot_id": "EXTL3_HUMAN", "id": "O43909-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GAGNGGQTCMLR---------------WSNRIRLTWLSFTLFVILVFFPLIAHYYLTTLDEADEAGKRIFGPRVGN--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--ATRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFVF---GSYLDPLVKQAFQATARANVYVTENADIACLYVILVGE-MQEPVVLR-----------------------PAELEKQLYSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGRAMVAQSTFYTVQYRPGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPRLVISSGCATRLFEALEVGAVPVVLG-EQVQLPYQDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEAAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPRYLRNFTLTVTDFYRSWNCAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ08-1", "uniprot_id": "EXT3_DROME", "id": "Q9XZ08-1", "name": "Exostosin-3", "aln": "MPPAYDLGHSGEAYQPLDTGSGGGNEACAPNSSSAQIRHSMGFRTSWMRQFRRYKLPMVLLMLLFLVSCLAYRILSVEQDAPPLDLHRSSPLLDAYEDFSAMRAGDLKMRIEEMVRIKSTVSVELRELESRRQKLQSDISQYNQKIEELKQELLREQTELERLKISVEQAQVAQREAVQRNTPDLALPRSLLPNTLPRKSNPITGGMAASCEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDLLRNNRYAAQEAEHQQPSTPTLENDCPVDMEK-LYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQNTMRAIVVQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMVPARRKYLLTYQG-ELRPKQSSLNPLDAFILEHLAD----------MAKGATQDQFVLQFQCVPATEQQEGDSLP-DWTLCGSDSSRRQLLKDSTFSLILPPLN-GRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQSVFNSTFIPLKSDPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRIPHDKQKCFKYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* : :.* * *.*.::* . * .::* *.:.*:::*.:.. :*: *:. ::* . : .* . ::. :: : :: **:.:** ** :**::**:*:*:*:: * *** *:.: . : :* :** :.*:: : :* : :* *.*:** ***:. * . : .*.:****::***.*******::**.*:. . * :* ::* ::: * *.::.::. **:*::**** : * :*: *.::** *.***:* **:***::**:*: *. * **. .* * *.**:* *:*.*:**:*.*:: . . : * . **.:****:*:** ::.. :***: :* * .* : *.**. : *. : ::* *** :*:***. ..* :*** ***:**:.* : : *: :*::***. *****:** ::::*** : ::*..:**::**.*:**:*****::.*:*** :*****::** *:*:.:: .:**:* :* *: **. *: . * .: : : . :** :. : : : . ****.** : **:*: : ..** .**:*:*: ****.*******:** ******* * **:**** :**** *****:********:***:** ** *****:* *:*: :*********:: *****:**:***********:******** ***:***********: *: .* ******************.**** ***:* :****** ****:*******************:************** :**.**:**:********* :*:** *** **:*.**:*****:**** ****:*", "identical_positions": 436, "similar_positions": 261, "identity": "44.22%" }, { "cls_id": "homologset.agr.HGNC:3519", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVI5-1", "uniprot_id": "D3ZVI5_RAT", "id": "D3ZVI5-1", "name": "Eyes absent homolog", "aln": "-------------------MEMQDLTSPHSRLSGSSE-----------SPSGPKLDSSHINSTSMTPNGTEVKTEPMSSSEIASTAADGSLDSFSGSALGSSSFSPRPAHPFSPPQIYPS-KPYPHILP--------------TPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQHYG-------------ISSYGALWAGIKTEGGLSQSQSPGQT-GFLSYGTSFGTPQPGQAPYSYQMQGSSFTTSSG-----------------------------LYTGNNS------------------------LTNS---SGFNSSQQD---YPSYPGFGQGQYAQYYNSSP----YPAHYMTSSNTSPTTPSTNAT-YQLQEPPSGVTSQAVTD-PTAEYSTIHSPSTPIKESDSD------------------------------------RLRRGSDGKS-RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRANCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97767-1", "uniprot_id": "EYA1_MOUSE", "id": "P97767-1", "name": "Protein phosphatase EYA1", "aln": "-------------------MEMQDLTSPHSRLSGSSE-----------SPSGPKLDSSHINSTSMTPNGTEVKTEPMSSSEIASTAADGSLDSFSGSALGSSSFSPRPAHPFSPPQIYPS-KSYPHILP--------------TPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYG-------------ISSYGALWAGIKTESGLSQSQSPGQT-GFLSYGTSFGTPQPGQAPYSYQMQGSSFTTSSG-----------------------------LYSGNNS------------------------LTNS---SGFNSSQQD---YPSYPGFGQGQYAQYYNSSP----YPAHYMTSSNTSPTTPSTNAT-YQLQEPPSGVTSQAVTD-PTAEYSTIHSPSTPIKETDSE------------------------------------RLRRGSDGKS-RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99502-1", "uniprot_id": "EYA1_HUMAN", "id": "Q99502-1", "name": "Protein phosphatase EYA1", "aln": "-------------------MEMQDLTSPHSRLSGSSE-----------SPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILP--------------TPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYG-------------ISSYGALWAGIKTEGGLSQSQSPGQT-GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSG-----------------------------IYTGNNS------------------------LTNS---SGFNSSQQD---YPSYPSFGQGQYAQYYNSSP----YPAHYMTSSNTSPTTPSTNAT-YQLQEPPSGITSQAVTD-PTAEYSTIHSPSTPIKDSDSD------------------------------------RLRRGSDGKS-RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9H5-1", "uniprot_id": "A0A8M2B9H5_DANRE", "id": "A0A8M2B9H5-1", "name": "Eyes absent homolog", "aln": "-------------------MEMQDLASPHSRVSGSSE-----------SPNGPNIDNSHINNNSMTPNGTEVKTEPMSSSEIATSVADGSLDSFSGSAIGTSGFSPRQTHQFSP-QIYPS-KPYPHILP--------------TPSAQNMAAYGQTQYTTGMQQAAAYGTYPQPGQPYG-------------ISAY-----GIKTEGGLTQAQSPGQS-GFLSYSSSFSTPQTGQAPYSYQMQGGSFTTTSG-----------------------------LYAGSNS------------------------LTNS---TGFNSTQQD---YPSYPTFGQSQYAQYYNSSP----YTSPYMTSNNTSPTTPSTTAT-YTLQEPPSGITSQALTEQPTGEYSTIHSPSTPIKDSDSD------------------------------------RLRRASDVKA-RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRFGRDPPTSVSLGLRMEEMIFNLADTHFFFNDLEECDQVHIDDVSSDDNGQDLSTYNFSTDGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSRSNCVNILVTTTQLIPALAKVLLYGLGVVFPIENIYSATKIGKESCFERVIQRFGRKVVYVVVGDGVEEEQGSKKHNMPFWRISSHSDLMALHHALDLEYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05201-1", "uniprot_id": "EYA_DROME", "id": "Q05201-1", "name": "Protein phosphatase eya", "aln": "MVTLMPYNYAAPRCGLIDKMIEPKVKRPKTDHTDTHERNRLCNLSQQQQQQQPQQQQTHQQQQQQQQQSHQQSHSSTVLASNGPSSAGAGMGVGVGGGGGSGGGVGGGVGQCSPLGLPPQSQPLQPTIGSLASLSGHYSNGNANPNVNSSSCSLATASSFAQSAGSSFSTYQQAGGTSGGVSGEDGVVGGATVMSHWTHDGTGSSAAVKSESRSPGQVHASLDNGSVAGSNLYGCSSASNPLDGGAVAVNSSAVAAAAAAVYDGKHDYYYYNSMQQYTPPPFYSGYGTPYAAATAARQAKMEPGAAAAAAAYLTPSYAASGNNNSQLYSSPYAGYNNFGQQDYGGYYNEQYGNYYSPANYSPYAVSSPSSSASHGHGFHVAASSNLSESPTDTHSTTPVHQTTHSPHSPLPISPSTGSGIGPLGNVSAAAAAAALNSSGGSSVGTAGSGGVATSKTTPTGKTGRARGRRHQQPSPTRSTASDTGNSEAVKPPERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFHTNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: *:: :.: * . . *: .:* :. . :. : . .. :. ..: *...:. *.. *:.. . ** : *. :. : .*. :. :. * : . . .:::.** *.* * : :: .: . ::::**** . *. .: .: * :. * ::*.:.:..*. :*:* .: ** * :* *.:* *..* *** :*. ***.. .: * . :**::.:: . : : ... * : *. .* :.* *** :*: : * : . *: *.****:::***. .: ****:******:*:**:**:******: :* .: :::.:*****:**:****:***::*********************:***.**** : :.. .****.******************::*:**.:*:.*** ****.*******:*:***. **.* *****.*::* .* ****:***:*** ********:*** :* ******* ***:*:*:**:: ***** .***:*** *** .:* :****:*:***: **: **:: :*", "identical_positions": 248, "similar_positions": 194, "identity": "32.38%" }, { "cls_id": "homologset.agr.HGNC:352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70200-1", "uniprot_id": "AIF1_MOUSE", "id": "O70200-1", "name": "Allograft inflammatory factor 1", "aln": "MSQSRDLQGGKAFGLLKAQQEERLEGINKQFLDDPKYSNDEDLPSKLEAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMYEEKNKEHKRPTGPPAKKAISELP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55009-1", "uniprot_id": "AIF1_RAT", "id": "P55009-1", "name": "Allograft inflammatory factor 1", "aln": "MSQSKDLQGGKAFGLLKAQQEERLDGINKHFLDDPKYSSDEDLQSKLEAFKTKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMYEEKNKEHQKPTGPPAKKAISELP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55008-1", "uniprot_id": "AIF1_HUMAN", "id": "P55008-1", "name": "Allograft inflammatory factor 1", "aln": "MSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAISELP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*******************: ***:********.**** ****.** ***********************************:** ****** *****.**************:******** :*:::**************", "identical_positions": 128, "similar_positions": 13, "identity": "87.07%" }, { "cls_id": "homologset.agr.HGNC:3520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1T5-1", "uniprot_id": "A0A0G2K1T5_RAT", "id": "A0A0G2K1T5-1", "name": "Eyes absent homolog", "aln": "MLEVVISPSLAASSD------WGEHGAAVGALTDREGTAKAASLSVPQLFAKSHPR-VPPGQSSAAMAAYGQTQYSTGIQQTPPYTAYP--------------------PPAQAYGIPPYSIKTEDSLNHSPSQSGFLSYG----------PSFSTAP-----AGQSPYTYPVHS-TAG------------------------------------------------------------------------------------------------------LYQG---------------------------------ANGLTNTAGFGSVHQDYP-----SYPNFPQNQYPQYFSPSYNPPYVP-----------------ASSLCSSPLST-STYVLQEAPHNVS------------------QSSESLAGDYNTHNGPST-PAKEGDTDRPHRASDGKL-RGRSKRSSDPSPAGDNE-----------IERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSTDGFHSTAPG---ASLCLGTGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGGLIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08575-1", "uniprot_id": "EYA2_MOUSE", "id": "O08575-1", "name": "Protein phosphatase EYA2", "aln": "MLEVVTSPSLATSSD------WSEHGAAVGTLSDREGIAKSAALSVPQLFVKSHPR-VPPGQSSTAMAAYGQTQYSTGIQQAPPYTAYP--------------------TPAQAYGIPPYSIKTEDSLNHSPSQSGFLSYG----------PSFSTAP-----AGQSPYTYPVHS-TAG------------------------------------------------------------------------------------------------------LYQG---------------------------------ANGLTNTAGFGSVHQDYP-----SYPSFSQNQYPQYFSPSYNPPYVP-----------------ASSLCSSPLST-STYVLQEAPHNVPS-----------------QSSESLAGDYNTHNGPST-PAKEGDTERPHRASDGKL-RGRSKRNSDPSPAGDNE-----------IERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSTDGFHSTAPG---ASLCLGTGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGGLIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00167-1", "uniprot_id": "EYA2_HUMAN", "id": "O00167-1", "name": "Protein phosphatase EYA2", "aln": "MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPR-VLPRQPSTAMAAYGQTQYSAGIQQATPYTAYP--------------------PPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG----------SSFSTSP-----TGQSPYTYQMHG-TTG------------------------------------------------------------------------------------------------------FYQG---------------------------------GNGLGNAAGFGSVHQDYP-----SYPGFPQSQYPQYYGSSYNPPYVP-----------------ASSICPSPLST-STYVLQEASHNVPN-----------------QSSESLAGEYNTHNGPST-PAKEGDTDRPHRASDGKL-RGRSKRSSDPSPAGDNE-----------IERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPG---ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05201-1", "uniprot_id": "EYA_DROME", "id": "Q05201-1", "name": "Protein phosphatase eya", "aln": "MVTLMPYNYAAPRCGLIDKMIEPKVKRPKTDHTDTHERNRLCNLSQQQQQQQPQQQQTHQQQQQQQQQSHQQSHSSTVLASNGPSSAGAGMGVGVGGGGGSGGGVGGGVGQCSPLGLPPQSQPLQPTIGSLASLSGHYSNGNANPNVNSSSCSLATASSFAQSAGSSFSTYQQAGGTSGGVSGEDGVVGGATVMSHWTHDGTGSSAAVKSESRSPGQVHASLDNGSVAGSNLYGCSSASNPLDGGAVAVNSSAVAAAAAAVYDGKHDYYYYNSMQQYTPPPFYSGYGTPYAAATAARQAKMEPGAAAAAAAYLTPSYAASGNNNSQLYSSPYAGYNNFGQQDYGGYYNEQYGNYYSPANYSPYAVSSPSSSASHGHGFHVAASSNLSESPTDTHSTTPVHQTTHSPHSPLPISPSTGSGIGPLGNVSAAAAAAALNSSGGSSVGTAGSGGVATSKTTPTGKTGRARGRRHQQPSPTRSTASDTGNSEAVKPPERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFHTNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: : .. . . :* . : . * * :. : . * . :: *:: *: : . * :* . ... *:*. * : ::. .. **. * * *::*:. :*.* ** . *:* :*.* ..* *: :.* : .* .* .: :.** :*:..: .**. :*.:. ** .* ** ::::.*. *: : *. *: .*.*. .* .*.. .: :. ** *.*.:* .:***: .. ***********:****:**:*::*.** ** :: : *.: ****:**:****:***::*:***:*:*************:***::****:.:* ..*** :**:**************::*::**:*:.*** *:*. ***:***:*:*:*. ** * * :**.*.:*..* ********:*** ********:***.:* ******* * *:*:*:***: *****:.*:***** *** .** *:******.*:*:.** **:: :*", "identical_positions": 234, "similar_positions": 170, "identity": "30.55%" }, { "cls_id": "homologset.agr.HGNC:35202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQH9-1", "uniprot_id": "D3ZQH9_RAT", "id": "D3ZQH9-1", "name": "", "aln": "MQCLPALARGAGRGEWSSGDPSAPALPSLASAPACLQRHSHCPLPLSGGDPGVRTAPYRPPRRRPAMAKRSSLSIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHMVAFYVMDEDALSRDDVIGKVCLTRDELTSHPKGFIGWTHLVEVDPNEEVQGEIHLRLEVVPGLHASRLRCSVLEARDLAPKDRNGASDPFVRVHYNGRTQETSVVKKSCYPRWNETFEFELEKGATEALLVEAWDWDLVSRNDFLGKVVVNVQTLCSAQQEEGWFRLQPDQSKSR-QGKGNLGSLQLEVRLRDETVLPSVYYQPLVQLLCQEVKLGTQGPGQLIPVIEETTSAECRQEVATTLLKLFLGQGLAKDLLDLLFQLELGRTSEANTLFRSNSLASKSMESFLKVAGMRYLHGILGPIIDRVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLVALLSAICRSVRTCPAVVRATFRQLFRRVRERFPSAQHQNVPFIAVTSFLCLRFFSPAILSPKLFHLRERHADARTSRTLLLLAKAVQNIGNMDTPVSRAKESWMEPLQPTVRQGVVQLKDFITKLVDIEEKEELDLQRALNLQAPPVKEGPLFIHRTKGKGPLASSSFKKLYFSLTTEALSFAKTSSSKKSVFIKLASIRAAEKVEEKSFGSSHVMQVIYSDDVGRAQTVYLQCKCVNELNQWLSALRKVITNNASLLGSYHPGVFRGDKWSCCHQKEKTDLGCDKTHSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAALREKHQLLSRATEEAGTSSTGRGGAPEDSLAQLLRVLRDLREAHSSSLASSPSREPRHLLELQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFQ7-1", "uniprot_id": "RASL2_MOUSE", "id": "Q6PFQ7-1", "name": "Ras GTPase-activating protein 4", "aln": "------------------------------------------------------------------MAKRSSLSIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEDYQVHLPPTFHTVAFYVMDEDALSRDDVIGKVCLTRDALASHPKGFSGWTHLVEVDPNEEVQGEIHLRLEVVPGVHASRLRCAVLEARDLAPKDRNGASDPFVRVHYNGRTQETSVVKKSCYPRWNETFDFELEKGASEALLVEAWDWDLVSRNDFLGKVAVNVQRLCSAQQEEGWFRLQPDQSKSR-QGKGNLGSLQLEVRLRDETVLPSVCYQPLVQLLCQEVKLGTQGPGRLIPVIEETTSAECRQEVATTLLKLFLGQGLAKDFLDLLFQLELGRTSEANTLFRSNSLASKSMESFLKVAGMRYLHGILGPIIDRVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLVALLSAICRSVRTCPAIIRATFRQLFRRVRERFPNAQHQNVPFIAVTSFLCLRFFSPAILSPKLFHLRERHADARTSRTLLLLAKAVQNIGNMDTPVSRAKESWMEPLQPTVRQGVAQLKDFIMKLVDIEEKEELDLQRALNSQAPPVKEGPLFIHRTKGKGPLASSSFKKLYFSLTTEALSFAKTSSSKKSTFIKLASIRAAEKVEEKSFGSSHIMQVIYADDVGRAQTVYLQCKCVNELNQWLSALRKASTNNRGLLRSYHPGIFRGDKWSCCHQKDKTDQGCDKTHSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAALRERYQLL-RGATEAGVSPTGCDGAPEDSLAQLLRVLQDLREAHGSSLASPAAREPHHLLELQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C9J798-1", "uniprot_id": "RAS4B_HUMAN", "id": "C9J798-1", "name": "Ras GTPase-activating protein 4B", "aln": "------------------------------------------------------------------MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVHQGVAQLKDFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAMLWERHREL-SGGAEAGTVPTSPGKVPEDSLARLLRVLQDLREAHSSSPAGSPPSEPNCLLELQT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******* ***********************************************:********** ************************* ::****** **:**.****:************* ** :*.****:**************:*******:*:***:***:*************:***::** *** ******************.::** * .***************** :.:******************** *****:***:***** ****:***:******:****:***.*************:*********.****:*************:*********:****:*****::********************************************** *****:.****:***::****************.***:********************:*****************************:******.*****:*********:***.****** ********:******:*. ********************* *********************.*****.:****.*************.**:*****:**.**.**.*******************. ** .** *****:************:**. *****:****************************** * *::: * . ***. .*. . .******:*****:******.** *.... **. ******", "identical_positions": 679, "similar_positions": 88, "identity": "78.05%" }, { "cls_id": "homologset.agr.HGNC:3521", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AMN9-1", "uniprot_id": "A0A8I6AMN9_RAT", "id": "A0A8I6AMN9-1", "name": "Eyes absent homolog", "aln": "---------------------------------------------MEEEQDLPERPVKKAKMQEPGEQTLSQVNN-------------------------------------------PDTSDQKPETASLASN-------------LSMSEEIMTCTDYIPRSSNDYTSQMYSAKPY------------AHILS-----------VPVSETTYPG-------------QTQYQTLQQSQPYAVYPQATQTYGLPPFGALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIPASSTNASLISTSSAIAN---------IPAAAVASISNQDYP---------TYTILGQNQYQACYPSSS------FGVTGQTN-----SDTENTA-LAATTYQTEKPGAMGP--------------APATQRLPS-DSSTS-------PPLSQTTPN-KDADDQARKNMTVKNRGKRKADASSSQDSE-LERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHG---SSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99504-1", "uniprot_id": "EYA3_HUMAN", "id": "Q99504-1", "name": "Protein phosphatase EYA3", "aln": "---------------------------------------------MEEEQDLPEQPVKKAKMQESGEQTISQVSN-------------------------------------------PDVSDQKPETSSLASN-------------LPMSEEIMTCTDYIPRSSNDYTSQMYSAKPY------------AHILS-----------VPVSETAYPG-------------QTQYQTLQQTQPYAVYPQATQTYGLPPFGALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTSSTIAN---------IPAAAVASISNQDYP---------TYTILGQNQYQACYPSSS------FGVTGQTN-----SDAESTT-LAATTYQSEKPSVMAP--------------APAAQRLSSGDPSTS-------PSLSQTTPS-KDTDDQSRKNMTSKNRGKRKADATSSQDSE-LERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHG---SSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97480-1", "uniprot_id": "EYA3_MOUSE", "id": "P97480-1", "name": "Protein phosphatase EYA3", "aln": "-------------------------------------------------------------MQEPREQTLSQVNN-------------------------------------------PDASDEKPETSSLASN-------------LSMSEEIMTCTDYIPRSSNDYTSQMYSAKPY------------AHILS-----------VPVSETTYPG-------------QTQYQTLQQSQPYAVYPQATQTYGLPPF----------------------------------------------ASSTNASLIPTSSAIAN---------IPAAAVASISNQDYP---------TYTILGQNQYQACYPSSS------FGVTGQTN-----SDAETTT-LAATTYQTEKPSAMVP--------------APATQRLPS-DSSAS-------PPLSQTTPN-KDADDQARKNMTVKNRGKRKADASSSQDSE-LERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHG---SSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCANVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05201-1", "uniprot_id": "EYA_DROME", "id": "Q05201-1", "name": "Protein phosphatase eya", "aln": "MVTLMPYNYAAPRCGLIDKMIEPKVKRPKTDHTDTHERNRLCNLSQQQQQQQPQQQQTHQQQQQQQQQSHQQSHSSTVLASNGPSSAGAGMGVGVGGGGGSGGGVGGGVGQCSPLGLPPQSQPLQPTIGSLASLSGHYSNGNANPNVNSSSCSLATASSFAQSAGSSFSTYQQAGGTSGGVSGEDGVVGGATVMSHWTHDGTGSSAAVKSESRSPGQVHASLDNGSVAGSNLYGCSSASNPLDGGAVAVNSSAVAAAAAAVYDGKHDYYYYNSMQQYTPPPFYSGYGTPYAAATAARQAKMEPGAAAAAAAYLTPSYAASGNNNSQLYSSPYAGYNNFGQQDYGGYYNEQYGNYYSPANYSPYAVSSPSSSASHGHGFHVAASSNLSESPTDTHSTTPVHQTTHSPHSPLPISPSTGSGIGPLGNVSAAAAAAALNSSGGSSVGTAGSGGVATSKTTPTGKTGRARGRRHQQPSPTRSTASDTGNSEAVKPPERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFHTNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :*: .* . *: . :* .**** . * .: *.:.: :...::: :. . * ::* . **: ** .. * . ::* . *.:: .:.. .::: *: *.* *. * *. .:.:*** *: . . * .. **** * *:..:* :*:..*: : **:....* : * *.*: * * . *: . *:***. * :.*:: . . :*: .*: : ****:******:****:**:****::* ** : :: .: ****:*::****:***::*******::**:********* *.*:**** . .*: ..**:***************:::**:.::.*** **.* ::** ::*:**** **.* ***.* :*..*:**.***:*:***.********:*** ** ******* ***:*:*:****:***:* ********.:** *** *:*****: *.*: :*: **::.**", "identical_positions": 226, "similar_positions": 163, "identity": "29.5%" }, { "cls_id": "homologset.agr.HGNC:3522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95677-1", "uniprot_id": "EYA4_HUMAN", "id": "O95677-1", "name": "Protein phosphatase EYA4", "aln": "----------------MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGE---------------------------------NMTVLNTADWLLSCNTPSSATMSLLAVKTE--PLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSG----MQQPAVYTAYSQTGQPYSLPTY--DLGVMLPAIKTESG---LSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP-GSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQN--------QYAQYYSASTYGAYMTSN--------------------NTADGTPSSTSTYQLQESLPG---LTNQPGE------FDTMQSPSTPIKDLDERTCRSSGS-------------KSRGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AS60-1", "uniprot_id": "A0A8I6AS60_RAT", "id": "A0A8I6AS60-1", "name": "Eyes absent homolog", "aln": "----------------MEDTQDLNEQSVKKTCPESDVSEPQNSRSMEMQDLASPHALVGGSDTPGSSKLDKSGLSSTSVTTNGTGGD---------------------------------NMTVLNTADWLLSCNTPSSATMSLLAVKTE--PLHSSETTTTTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSG----MQQPAVYTAYSQTGQPYSLPAY--DLGVMLPAIKTESG---LPQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP-GSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQN--------QYAQYYSASTYGAYMTSN--------------------NTADGTSSSTSTYQLQESLQG---LTSQPGE------FDTVQSPSTPIKDLDDRTCRSSGS-------------KSRGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHATASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z191-1", "uniprot_id": "EYA4_MOUSE", "id": "Q9Z191-1", "name": "Protein phosphatase EYA4", "aln": "----------------MEDTQDLNEQSVKKTCPEADVSEPQNSRSMEMQDLASPHALVGGSDTPGSSKLDKSGLSSTSVTTNGTG--------------------------------------------------------VSLLAVKTE--PLHSSESTTTTGDGALDTFTGSVITSSGYSPRSAQQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSG----MQQPAVYTAYSQTGQPYSLPAY--DLGVMLPAIKTESG---LSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP-GSSFAPSSTIYANNSVSNSTNFSSSQQDYPSYTAFGQN--------QYAQYYSASTYGAYMTSN--------------------NTADGTSSSTSTYQLQESLQG---LTSQPGE------FDTVQSPSTPIKDLDDRTCRSSGS-------------KSRGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNMPFWRISSHSDLLALHQALELEYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58IJR1-1", "uniprot_id": "A0AC58IJR1_DANRE", "id": "A0AC58IJR1-1", "name": "Eyes absent homolog", "aln": "----------------MENTQDLNEQSVKKSTTDSHAPDPVDNRALEMQELTDVQHSVN-SGSDGTSKLDKNILSNN-ITTNGTGGE---------------------------------NMTILNTADWLLGCSSPPTAPSMKNDVKSE--PLNSSEAVSSAGDSGLDTYTGSVISSSGFSPRPAHQYSPPLYPSKPYPHILTTPVAPPMSAYTGQSQFSS----MQQSTVYTPYSQTTPPYGLSTYATDLGVMLPGIKTEGG---LTQTQSTLQSG-LSYSPGFTTPQPGQTAYSPYQMPAGSGFTTSPGLYTSN-NSNPGNFTTQQQEYPSYTTFGQN--------QYAQYYSTSSYGSYMTSN--------------------SSLDGTG-SVSTYQLQDPIMTGQAADLNPGE------FEAGQSPSTPIKEMEDRACRGGGA-------------KARGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATS---ASLCLATGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05201-1", "uniprot_id": "EYA_DROME", "id": "Q05201-1", "name": "Protein phosphatase eya", "aln": "MVTLMPYNYAAPRCGLIDKMIEPKVKRPKTDHTDTHERNRLCNLSQQQQQQQPQQQQTHQQQQQQQQQSHQQSHSSTVLASNGPSSAGAGMGVGVGGGGGSGGGVGGGVGQCSPLGLPPQSQPLQPTIGSLASLSGHYSNGNANPNVNSSSCSLATASSFAQSAGSSFSTYQQAGGTSGGVSGEDGVVGGATVMSHWTHDGTGSSAAVKSESRSPGQVHASLDNGSVAGSNLYGCSSASNPLDGGAVAVNSSAVAAAAAAVYDGKHDYYYYNSMQQYTPPPFYSGYGTPYAAATAARQAKMEPGAAAAAAAYLTPSYAASGNNNSQLYSSPYAGYNNFGQQDYGGYYNEQYGNYYSPANYSPYAVSSPSSSASHGHGFHVAASSNLSESPTDTHSTTPVHQTTHSPHSPLPISPSTGSGIGPLGNVSAAAAAAALNSSGGSSVGTAGSGGVATSKTTPTGKTGRARGRRHQQPSPTRSTASDTGNSEAVKPPERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFHTNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : : : *. .::. : . : : *: : . .: .:. *.. :::**.. *::. .* ::.: : :....:.*: : :*.* * . . .. : . .: ::... . * .** : * : . :* * : . .. . .* .. . .* :* * .: .*: ** .. *. :* *:. :.:. : .. *. * .. *..*. ***: **.:***.:.*..* .*. .: .* :...:* .. ..*. : :.::.::. : .*: ..*.***::: ***. .: ***********:*:**:**:****::* ** . :*:.:*****:**:****:***::**********.*********.:*.*******: :.. ..***.******************::*::* :*:.*** ****.**:****:*:*:* **.* * ***.**:** *.**:*****:*** ********:.**. * ******* ***:*:*:***: *** : .******* :** **. *:******:***: **: **:: :*", "identical_positions": 235, "similar_positions": 210, "identity": "30.68%" }, { "cls_id": "homologset.agr.HGNC:35237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0S6J3-1", "uniprot_id": "SRGP2_DANRE", "id": "B0S6J3-1", "name": "SLIT-ROBO Rho GTPase-activating protein 2", "aln": "MTSPAKFRKDKEIIAEYETQVKEIRAQLVEQLKCLDQQCELRVQLLQDLQDFFRKKAEIEMDYSRNLEKLAERFLAKTRYTKDPQFKKEQNILSPVNCWNLLLAQVKRESRDHATLSDLYLNNIIPRFAQISEDSGRLFKKSKEVGLQLQEDLMKVLNELYTVMKTYHMYNMDSINAESKLKEAEKQEEKQMSRSVRHEEKQTPRSPDSLTNIKIEDKHVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLLALEATNSCVFKYYIHDLSDLIDCCDLGYHASLNRALRTYLSAEFNVETSKHGGLETIENAAENLEANSDKQRLMETYNNVFCPPMRFDFQSHMGDMVGHLCAQQPVQGELIQRCQQLQSRLSTLNIENEEVKKTMEATLQTIQDMVTIEDFDVTDCFHHSNSMESVKSTVSESFMSKPSLAKRRANQQETEQFYFTKLKEFLEGRNLITKLQAKHDLIQKTLGESQKTDYCLASGRRDSTVRKQEAIQIIPLMVESCIRFISRHGLHHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLENALFPKEVFHDLMSCVSIESLQERAVHIRKVLLSLPSNILVIMRYLFAFLNHLSQYSDDNMMDPYNLAICFGPTLMSVPEGHDQVSCQAHVNELIKTIIIHHESIFPGPRELEGPVYDRGGAPEEYCDSPHIEPPLVDEPAPDTVSVIHNSDDVKSGPLTVSESDPIEAIARFDYSGRTNRELSFKKGASLLLYSRASDDWWEGRHNGTEGLVPHQYIVVQDMPDGYAGRGSPKADLEGSHDSVEEKVSTRASASSPTGGHVADIYLANLNKLRKRPEATSIRRTIRPVEEGSSGAAGGLKTSSMPAGGLAKDSSDKRPVSAHSVLNSITRHSSLKTKVEGPQVRKSTPTGRSKSFSNHRPLDPEVIAQVEHSSQDIEATMNTALSELRELERQSNVKHAPDVVLDTLEQLKSGGTSEPSSPLHSRLLREAESSQHPLQRSASSASDMPSTFRPSKTTGPKSPLSSMTTASGSTFRDNKPPATRPKPVVFPKSSSAGGSPAMGSPTTTIPPTPPPPPPPTDKSCPV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0DMP2-1", "uniprot_id": "SRG2B_HUMAN", "id": "P0DMP2-1", "name": "SLIT-ROBO Rho GTPase-activating protein 2B", "aln": "MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIEMDYSRNLEKLAERFLAKTCSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIYLNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQPVQSELLQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETFMSKPSIAKRRANQQETEQFYFT---------------------------------------------------------VRECYGF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:*********:**********.**:********************************************** *** ****:**:*********** *********:****:*********.*:*************** ***:**********:********* ***.*:*************:.:**::*::******** :*::**:********************************************:.******************************:****:*:* *** **::****.***:*.******** *********:*:**.*****..:********.**:*************:*******************:**:*****:***::*************:******:**************** *..* * ", "identical_positions": 393, "similar_positions": 53, "identity": "35.73%" }, { "cls_id": "homologset.agr.HGNC:35240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTU7-1", "uniprot_id": "D3ZTU7_RAT", "id": "D3ZTU7-1", "name": "", "aln": "MVLLAGPGPEGG----------------------GTRCLSPQSPTPPRSVQTGDDP----------------ADYEEYEDFSSLPDTRSIASDDSFYPPGGEEECGSVCAESVPEG----VPESATLLRAACANDVGLLRALVRRGPSSEEARETDRNGRTGLIIACYHGFVDTVVALAECPHIDVNWQDSEGNTALITAAQAGHATITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMLAGADVQARDPRRGLSPQEWAAYTGRAEAVRVMQRLMERPCPEQFGDKYKLELPLPAETILKKAGSKNCLQRFTAFLRSTLTSRS-GQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLDAQAQDSNNVEL------QSQILETPRASSR--SPQS-----LGSGSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRAPRWRKRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U0L2-1", "uniprot_id": "AN33B_MOUSE", "id": "Q3U0L2-1", "name": "Ankyrin repeat domain-containing protein 33B", "aln": "MVLLAGPGPEGG----------------------GTRCLSPQSPTPPRSEQTGEDP----------------ADYEEYEDFSSLPDTRSIASDDSFYPPGGEEEYGSVSAESVPEG----VPEAATLLRAACANDVGLLRALVRRGPSSEEVRETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEAVRVIQRLMERPCPEQFGDKYKLELPLPAEAVLKKSGSKNCLQRFTAFLRSTLTSRSSGQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLNAQAQDSNKVECSE---PQSQILETPRASSR--SPKSP----AASRSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKEKRAPRWRKRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NCL7-1", "uniprot_id": "AN33B_HUMAN", "id": "A6NCL7-1", "name": "Ankyrin repeat domain-containing protein 33B", "aln": "MVLLAGTGPEGG----------------------GARCMTPPPPSPPRGAQVEEDP----------------ADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRS-VRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG-A---GQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLN2-1", "uniprot_id": "A0A8M9PLN2_DANRE", "id": "A0A8M9PLN2-1", "name": "", "aln": "MVLITENGVAGGVVLVKVHKHDTEDNRARGWTNEESSIQSSTVVEPNEDSYYADDDEDHHFYDDDDDDDDVYQEFEELD-FSKLPDSRSMASDDSFYPP--DDSLS-FEKCPSPES-----PEPVSFFKACCSNNVIIVKIMIRQGVTEAEVREVDKNNRTGLIVACYQGYVDVVIALSQCPHVDVNWQDNEGNTALINAAQAGHSMITHYLLNYFPGIDTERRNCHGFTALMKAAMQGRAECVRSLMMTGGDIEARDFGRKLTPQEWALFTGRYETAKLISRLMDKPCAEQFCDSYHMGWPMLSEMVARSKEPKSCWRKFSECICNMFNISMKTNPVDEG-VMDYTVRMTTALASPLIATACHTVCPGSPPCVGKRRPAVQDILRRQRLAELKNLGPDRLNNYKRLFQNSRVLLVPKKQERRASLQPQL--LHSVAMASTVALRRNSLLPLHMMRRSSVRPGMVVPKVMLCKAPPPIHMPERPPRRSS-NDSAQLQIPKWKYKALKEEKKKAEQMER--------LRLPIGRKK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UVK1-1", "uniprot_id": "A0A8N7UVK1_DANRE", "id": "A0A8N7UVK1-1", "name": "", "aln": "MVLITDSRDGGG----------SSPGKVKPLKHAKGAQICPTIVEESPD-HTGNDDYDEFLGTCEFDGN--NEDFEELDDFSELPDTRSIASDDSFYPP--DDDFADSERTPSPES-----PAPLSFFQACCGNNALIVKLMIRQGVTEEDVRETDKNKRTGLIVACYQGYVDVVMALSQCPHLDVNWSDNEGNTALITASQAGHITICNYLLNYFPGLDIEKRNCHGFSALMKAAMQGRVECVKALMMAGADLEARDNGRKFTAREWAIFTSRHETVLTIMRLMHQPCADQFCDSYRPEWPLLPALVAKAQAPKGCIQKISETLRDFFDISNVTEASEDG-VLDHMVRMTTALGSPFIATSCRTVCPGSPPCVGKRRYAVQEILKKRRIEQLKILGPERIENYKRLFQNSRVLLVPKPKDRRASLQPN----AQAEDSSTLTIRRTSLLPLHLLRRSSVRPGLVVPKVRITKAPTPTYVPERVRRKSSCVEEQFLQIPKWRYKELKEERKKAEEAERKRLEAITKRQLTTGKRK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:: ** . . :* ::** : **.***:**:******** ::. . . **. * . ::::*.*.*:. ::: ::*:* : :.:*.*:* *****:***:*:**.*:**::***:****.*.*******.*:**** * :********:* *:** .**:**********.:*:::**::*.*:.*** * ::.:*** :*.* ::. : **:.:**.:** :.*: * . : .*.* :::: : . : . ::* *:*: *****:* ** :* *:**** .**.***** ***:** : : :.: : ..* * :. ..: . *: *****: :** *****:***:* : ***.* . *** :.. :. ******:** ***::***: *: : . :* ", "identical_positions": 188, "similar_positions": 140, "identity": "35.01%" }, { "cls_id": "homologset.agr.HGNC:35241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3T8-1", "uniprot_id": "M0R3T8_RAT", "id": "M0R3T8-1", "name": "", "aln": "MKKIFGFRNKGPSPLGSSARPRSNCVGFGRENASGSHVPRYHIHDKDMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDACDSENSTALIKAVQCQEEECAAILLDHGADTNVTDSSGNTALHYAVYCESTSIAAKLLARGANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKTSIHAADQLGSNRQIFEYDGKRPKNSENSNAVDNVSEDGSLTRSSHIPDPADSWPTSDEDDYNFDTKNVPKINLTELWTAAQQSKKNQTKCGFEEPDSRALFDDSNSASENEDATGIEPESPARVQTLSPSCQSPDPVEGAADPAIEGEENGKDIIESASQEQSHDSLVRADGWHRSNKSEMMSALGLGEDEDEDSPWDSESLSESVSLDGVAPLSGTEDHTGKRRARGQIEDVTYIPSCMSGSRSFKMAKLEESRTVGIPVAHMEAPRRCPIMKPAVERRAPVLNKSETVGMKDVQTFKPEPEEQTRLRGSEDSQQKVEER-RKYRNNEAEPSGNLYAGAADCAADGNPPRGNTDDLQFPRKGSEGHGSGPTLLMKEAEKTENEKWVSKESVMMAVTESAGLPTGGSLQMQDGSHLSDSDQSESRPAKKTSNKNNKDSKQTAAVDNLDNLTESSEMSSEDHELQGPDYERILCEIEHLRLECKDTVSLLKIRDAVYSYKRLIELKRSHCELLTGKLKRVESKCKGLQKEVSETEEVRSRLEHEKLAWEQELCSLRFALKQEEEKRRSADQLSERMVEQLRRKGEQYQGEVEARQQLEVSLRSLEMELKTVRSHLNQVLEERNETQRQLSREQNARMLQDGILANHLCKQKEIEMEQKKMTSEASLSHEKEKDLLHKNQRLQDEVAMLKLEMDTIKNHNLEKERKYLEDIKIANEKNDNLQRMIKLNEETFTKTIFQYSGQLNNLKTENAMLSSRLDNEKQSKERLETDVESFRSRLASALHEHAEIQTAKRDLETAFQRAKDEWFRLKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLETEFHHTQGELREKTLALKCVQRDLSQTQSQMKEVEHMFQDEQGKVNKYMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDRTIVSIQDQFQEMLNRVQAESQKHSLRLEDRNQELIIECSHLKERMCQYENEKAEREVAVRQLQQELADTLKKQSMSEASLEVSSRYRSSLEEEARDLKKNLSQLRSQLQEAQDQHREAVQRAEKMQDHLQKLELENSKFKITIKTQSEEIEQLQENLSNGNLSEEDQEKLKKLTELKESLEYTLDQEQKRSDALEKELTEFKEVLKMTKKELSEYENRELHLHQDMKSSQLEMDVPVNALVKKIDDLTEKLETASSKCLHLGKRNQLLQQELLLMKTLQKKCGKLEKSKRKLEQEVASLRSHIEENMVEHSRVQQYAREVEDRARQDLVEKLKQVNLFLQAQAASQENLEQLRENSNASLRSQMELRIQDLESQLYKMKAQEDFDKIELEKYKQLYQEEFRVRKALSSKLNRTTERLEETSTKLLLEEQQNRSLLSSLSTRPVVECPCVGKLHNSLVLNRTLIPRESLAVPTSGLQPSNKRVEIFLTKMHQELEKSINRELKEATAELESEFCRVSPLGSATKPGQDLLSEASQEYIDILKKKYMIC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NC57-1", "uniprot_id": "ANR62_HUMAN", "id": "A6NC57-1", "name": "Ankyrin repeat domain-containing protein 62", "aln": "------MEVRG-SFLAACRRRMATWR--KNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGR---------------------------------------------------------------TALILAAR--------------------------------------------------------------------NGSTSVVYQLLQHNIDVFC-----------------------QDISGWTAEDYAVASKFQAIR---------------GMISEYKANKRCKSLQNSNSEQDLEMTSEG----------------------------------------------EQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYND------DVDELIHKIKN---------------RKPDNHQSPGKE-----------------------------NGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFH----------------------------------------------THERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTN-------SHIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECR----KLEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLGQMRSQVCMKLSMSTVTL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :* * *.:. * :. ..: .* * *::::**:* ***** .*** ** . ::* ..:******:**** ****:*:* **: ** ***::: **** ************ **:***:***:.** * ********: *. *:* **** **:***:.:*. *.:****:.:*:::* **:***..: * *::* * * **: **. : ::. * : :: * * :*. : : .::.: * *.: . * * ..* . .** : ** **.*.*.** :***: :* **:: * * *::*. :* * :.*:* . *. .*.:*.: .** : . .* *:****::.* ..* .*:*:::: *** :***.** .* *.:: **: :**** *** * ::*. : * ** ::.:** *. *:::::.: . *** :***::.:*: **::* :::**.*** *:*:**:* .*::* *: :*:*: ***: :.*.::* :::*:***:*******: ** :. :**:*:** ::*: ::**:* *:**:****::* *.*.**::**:* :*:*::*:: :* ***::**** :** :** * **:**.*.*::**** .****::**:*.***:** :* : *::****: *** : :** :*::. * .: ::*******:* . ..****:*: : *:**** :: :* **:** :::::***:*::* ::**: **:*:*: * ****:* * :** :** :**:.:::**:.** : :: ::::***.: :**:.*: *: **: **** ****:** ****. ****:*: *:*:** : ** **:**. * .**:**:.***:*.*:***: . :: ", "identical_positions": 409, "similar_positions": 309, "identity": "24.4%" }, { "cls_id": "homologset.agr.HGNC:35245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5KM66-1", "uniprot_id": "SYCE3_MOUSE", "id": "B5KM66-1", "name": "Synaptonemal complex central element protein 3", "aln": "MADSDPGERSYDNMLKMLSDLNKDLEKLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDD6-1", "uniprot_id": "D3ZDD6_RAT", "id": "D3ZDD6-1", "name": "", "aln": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1L190-1", "uniprot_id": "SYCE3_HUMAN", "id": "A1L190-1", "name": "Synaptonemal complex central element protein 3", "aln": "MDDADPEERNYDNMLKMLSDLNKDLEKLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFVNCKEEMEKNWQELLHETKQRL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:** **.****************:***************************************:************** ***:: ", "identical_positions": 78, "similar_positions": 6, "identity": "88.64%" }, { "cls_id": "homologset.agr.HGNC:3526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZH3-1", "uniprot_id": "F1LZH3_RAT", "id": "F1LZH3-1", "name": "[histone H3]-lysine(27) N-trimethyltransferase", "aln": "VRKMDIASPP------TSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQLLNEEWKKLRVQPVQPMKPVSGHPFLKKCTIESIFPGFDSQDMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEE---MIPGSVLISDAVFLELVDALNQYSD-EEEEGHNDTSDGKQDDSKEDLPVTR--------------KRK-RHAIEGNKKSSKKQ-------------------------FPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNVYKRKNREIKIEPEPCGADCFLWLEGAKEYAMLHNPRSKCSGRRRRRHPVVSASCSNTSASAMAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLP-TDELMNPSQKKKRKHRLWAAHCRKIQLKKDNNSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCSPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70351-1", "uniprot_id": "EZH1_MOUSE", "id": "P70351-1", "name": "Histone-lysine N-methyltransferase EZH1", "aln": "---MDIASPP------TSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQPMKPVSGHPFLKKCTIESIFPGFDSQDMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEE---MIPGSVLISDAVFLELVDALNQYSD-EEEDGHNDPSDGKQDDSKEDLPVTR--------------KRK-RHAIEGNKKSSKKQ-------------------------FPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHPVVSASCSNASASAMAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPAQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLP-TDELMNPAQKKKRKHRLWAAHCRKIQLKKDNNSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCSPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92800-1", "uniprot_id": "EZH1_HUMAN", "id": "Q92800-1", "name": "Histone-lysine N-methyltransferase EZH1", "aln": "---MEIPNPP------TSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEE---MIPGSVLISDAVFLELVDALNQYSD-EEEEGHNDTSDGKQDDSKEDLPVTR--------------KRK-RHAIEGNKKSSKKQ-------------------------FPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLP-TDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFB7-1", "uniprot_id": "E7FFB7_DANRE", "id": "E7FFB7-1", "name": "[histone H3]-lysine(27) N-trimethyltransferase", "aln": "---MEEVSGPRPCTVKPRQDLLEWKKRVKSEYMRLRQLKRFRKAEQVKALFQSNRRKIEVGTELLNEEWSKLRIQSIPLSTSSGSLPSKKLCMVEFGFPSFPNQAVAMRPLTTVAGIPFMYSWSPLQQNFMVEDETFLHNIPYMGDEVLEQDEAFLEELIDNYDG-VHGDRVSCTFLIEGGFINDEIFKELVEALSQYSDPEEEEEEKEPTDAAENKQEEEKEMQKSAAEAPEESKTAFFKRKWRNTAEGRELSANKK-------------------------IPHDKIFTAIASMFPYKGTMQELKDKYLDLLEPSNHVKLPPLCTPNMDGPFAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--SSPNVYKRKSKEIHMETEPCGLDCFLLQKGAKEFADQNMMRSQRT-RRRRRQPRPSSSCGHTPPDSSEKGKEGGSDHET-----TSSSEGNSRCPSPIKMKPGEEESK----ESKS-PPQWSGAEESLFRVLHGTYYNNFCSIARLIGTKTCREVYEFAVKEVLIDRMP-LEDSGISPQKKKRKHRLWA----KIQLKKDNSSNQVYNYQPCDHPEHPCDSSCPCVITQNFCEKFCQCDRECQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCMTCGAADHWDSKQVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKEPVQKNEFISEYCGELISQDEADRRGRIYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQQGEELFFDYRYSQADALKYVGIEREIEIV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42124-1", "uniprot_id": "EZ_DROME", "id": "P42124-1", "name": "Histone-lysine N-methyltransferase E(z)", "aln": "---MNSTKVP-----------PEWKRRVKSEYIKIRQQKRYKRADEIKEAWIRNWDEHNHNVQDLYCESKVWQAKPYDP--PHVDCVKRAEVTSYNGIPSGP-QKVPICVINAVTPIPTMYTWAPTQQNFMVEDETVLHNIPYMGDEVLDKDGKFIEELIKNYDGKVHGDKD-------PSFMDDAIFVELVHALMRSYSKELEEAAPGTATAIKTETLAKSKQGEDDGVVDVDADGESPMKLEKTDSKGDLTEVEKKETEEPLETEDADVKPDVEEVKDKLPFPAPIIFQAISANFPDKGTAQELKEKYIELTEHQDP-ERPQECTPNIDGIKAESVSRERTMHSFHTLFCRRCFKYDCFLHRLQGHAGPNLQKRRYPELKPFAEPCSNSCYMLIDGMKEKLAADS------------KTPPIDSCNEASSEDSNDSNSQFSNKDFN---HENSKDNGLTVNSAAVAEINSIMAG--MMNITSTQCVWTGADQALYRVLHKVYLKNYCAIAHNMLTKTCRQVYEFAQKEDAEFSFEDLRQDFTPPRKKKKKQRLWSLHCRKIQLKKDSSSNHVYNYTPCDHPGHPCDMNCSCIQTQNFCEKFCNCSSDCQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCQACG-ADQFKLTKITCKNVCVQRGLHKHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDHRIGIFAKRAIQPGEELFFDYRYGPTEQLKFVGIEREMEIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . * **::*****:::** ** : * : * : : .: * * . : :. . . :*. * : : :.:*: :* **:*:* **********.* ********* ::* *:****.**** ***:. ::.* :* ***.** : . * *: .: . : . . . : : :* . :*: :* ** **:: ** :*. :::*::* :* * .: * ****:** *:**.**:::******************* :: : **: **: *:: .***. .*:: .* ** . : **..:... . :. *::: .*.: . :. : . . : * *:**:::*:**:* .* :*:*:**: : ****::*::** ** : : ..:***:*:***: *******..*.:**** ***** :*** .*.*: *********:*. :***********:********************* :** ::::. . ::*** .:****:****:****:**** *:** .************:**********::*****.***************************:********:**.************** **********. :: **:****** ::.", "identical_positions": 341, "similar_positions": 180, "identity": "42.47%" }, { "cls_id": "homologset.agr.HGNC:3527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHI4-1", "uniprot_id": "A0A8I6AHI4_RAT", "id": "A0A8I6AHI4-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "MRIIMGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKTMFSSNRQKILERTETLNQEWKQRRIQPVHIMTSVSSLRGTRECSVTSDL-DFPAQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALG---------------------------QYNDD---DDDDDGDDPDEREEK-------QKDLDDSRDDKETC------------PPRKFPADKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNTYKRKNTETALDNKPCGPQCYQHLEG---AKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTISVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPVPTEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61188-1", "uniprot_id": "EZH2_MOUSE", "id": "Q61188-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "----MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKTMFSSNRQKILERTETLNQEWKQRRIQPVHIMTSVSSLRGTRECSVTSDL-DFPAQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALG---------------------------QYNDD---DDDDDGDDPDEREEK-------QKDLEDNRDDKETC------------PPRKFPADKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNTYKRKNTETALDNKPCGPQCYQHLEG---AKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTISVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPVPTEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15910-1", "uniprot_id": "EZH2_HUMAN", "id": "Q15910-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "----MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDL-DFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALG---------------------------QYNDD---DDDDDGDDPEEREEK-------QKDLEDHRDDKESR------------PPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNTYKRKNTETALDNKPCGPQCYQHLEG---AKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BS4-1", "uniprot_id": "EZH2_DANRE", "id": "Q08BS4-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "----MGLTGRKSEKGPVCWRRRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTDILNQEWKLRRIQPVHIMTPVSSLRGTRECTVDSGFSEFSRQVIPLKTLNAVASVPVMYSWSPLQQNFMVEDETVLHNIPYMGDEILDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALN---------------------------QYSDN---EEDDEEDDHHDYKFE-------KMDLCDGKDDAEDHKEQLSSESHNNDGSKKFPSDKIFEAISSMFPDKGSTEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFQ--ATPNTYKRKNMENLVDSKPCGIYCYMYMVQDGMVREYPAGVVPERAKTPSKRSTGRRRGRLPNSNSRPSTPTVNS-ETKDTDSDREGGAD-GNDSNDKDDDDKKDETTSSSEANSRCQTPVKLKLSSEPPENVDWSGAEASLFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIARAPAVDENTPQRKKKRKHRLWATHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVTAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAAEHWDSKNVSCKNCSIQRGAKKHLLLAPSDVAGWGIFIKEPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42124-1", "uniprot_id": "EZ_DROME", "id": "P42124-1", "name": "Histone-lysine N-methyltransferase E(z)", "aln": "---------MNSTKVPPEWKRRVKSEYIKIRQQKRYKRADEIKEAWIRNWDEHNHNVQDLYCESKVWQAKPYDPPHVDCVKR--AEVTSYNGI-PSGPQKVPICVINAVTPIPTMYTWAPTQQNFMVEDETVLHNIPYMGDEVLDKDGKFIEELIKNYDGKVHGDKDPSFMDDAIFVELVHALMRSYSKELEEAAPGTATAIKTETLAKSKQGEDDGVVDVDADGESPMKLEKTDSKGDLTEVEKKETEEPLETEDADVKPDVEEVKDKLPFPAPIIFQAISANFPDKGTAQELKEKYIELTEHQDP-ERPQECTPNIDGIKAESVSRERTMHSFHTLFCRRCFKYDCFLHRLQGHAGPNLQKRRYPELKPFAEPCSNSCYMLIDG--------------------------MKEKLAADSKTPPIDSCNEASSEDSND-----SNSQFSNKDFNHENSKDNGLTVNSAAVAEINSIMAGMMNITSTQCVWTGADQALYRVLHKVYLKNYCAIAHNMLTKTCRQVYEFAQKEDAEFSFEDLRQDFTPPRKKKKKQRLWSLHCRKIQLKKDSSSNHVYNYTPCDHPGHPCDMNCSCIQTQNFCEKFCNCSSDCQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCQACG-ADQFKLTKITCKNVCVQRGLHKHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDHRIGIFAKRAIQPGEELFFDYRYGPTEQLKFVGIEREMEIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * * *::******:::** **::****:* : * :: ...: * * * : :* . . * * : ..: * :*: .:***:.:* **:*:* *********************:**:**.****************:: .*::* ******:** * .*: : * : :. . : : : : .: * **: **:***: *****:::****** ****:* * * ******** :*:**.**:::******************* :: * ** **: * :**. ** : : :*. ... *. : . .::*::. :: ..:* :.::.**: : ..* ..: .. : *:**: :::*** .* .*:****: : ********** **.: :: : ** ****:*:***: **********.******** ***** :*** .*.*: :********:***:********************************* :** *:::. .:::*** .:*** :****:****:******:*: .**********************************************************:***********.**************.**********. :: **:********* ", "identical_positions": 399, "similar_positions": 159, "identity": "49.57%" }, { "cls_id": "homologset.agr.HGNC:3528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63207-1", "uniprot_id": "FA10_RAT", "id": "Q63207-1", "name": "Coagulation factor X", "aln": "MESPVRLSLLYVVLASLLLPGRSVFINRERANNVLQRIRRANSFFEEIKKGNLERECVEEICSFEEAREVFEDNEKTTEFWNKYEDGDQCESSPCQNQGECRDGLGSYTCTCTEGFEGKNCELFVRKLCSLDNGDCDQFCREEQNSVVCSCAKGYFLGNDGKSCLSTAPFPCGKTNKGRAKRSVALNTSNSEPDPEDLMP---DADILYPTESPS-------------ELLNLNKTEPEANSDDVIRIVGGQECKRGECPWQALLFSDEETDGFCGGTILNEFYILTAAHCLHQAKRFKVRVGDLNTEQEDGGEMVHEVDMIIKHNKFQRDTYDFDIAMLRLKTPITFRENVAPACLPQKDWAEATLMTQKTGIVSGFGRTHEKGRQSKVLKMMEVPYVDRNTCRLSTSFSITQNMFCAGYDAKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKARVGPTSETPR---LTHPPY-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88947-1", "uniprot_id": "FA10_MOUSE", "id": "O88947-1", "name": "Coagulation factor X", "aln": "MGSPVQLSLLCVVLASLLLPGKGVFINRERANNVLARTRRANSFFEEFKKGNLERECMEEICSYEEVREIFEDDEKTKEYWTKYKDGDQCESSPCQNQGACRDGIGGYTCTCSEGFEGKNCELFVRKLCRLDNGDCDQFCREEQNSVVCSCASGYFLGNDGKSCISTAPFPCGKITTGRRKRSVALNTSDSELDLEDALL---DEDFLSPTENPI-------------ELLNLNETQPERSSDDLVRIVGGRECKDGECPWQALLIN-EDNEGFCGGTILNEFYILTAAHCLHQARRFKVRVGDRNTEKEEGNEMVHEVDVVIKHNKFQRDTYDYDIAVLRLKTPITFRMNVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCKLSTSFSITQNMFCAGYEAKLEDACQGDSGGPHVTRFKNTYYVTGIVSWGEGCARKGKYGIYTKVTTFLKWIDRSMKARVGPTAETPR---TAGPPN-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00742-1", "uniprot_id": "FA10_HUMAN", "id": "P00742-1", "name": "Coagulation factor X", "aln": "MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPF-------------DLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLIN-EENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QLC3-1", "uniprot_id": "F1QLC3_DANRE", "id": "F1QLC3-1", "name": "coagulation factor Xa", "aln": "MS---WVFWNFISLFVTHSVCAEVFLNTRDANQVLIRQRRANSLFEEMKKGNMERECIEERCNYEEAREIFEDVKKTDEFWHKYVDGDACLSHPCVNGGQCKDAIGPYTCFCQQGFKGYNCEIVIPELCENENGGCDHFCEVMEKNVVCSCANGYELAPNGKSCQSQDPFKCGVIYPKKTRSIFFHTPNITESENEEETELEATIEPVYNHSNPLNNQTDSMFGLHELEIIEEEPILPVVSTAGDGRIVNGVECPPGDCPWQALLIN-ENNMGFCGGTILTEHFILSAAHCMNESLSIRVVVGEYDTLVPEGREATHDVDEILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPACLPEMKFAERVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGYDQEEKDACQGDSGGPHVTRFKNTWFITGVVSWGEGCARKGKYGVYTQVSKYIMWINNAMTKVMPETGASLKPKAKRELRHKTPIRRV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * :*:. . **::* * ****::**:***::****:** *.:**.**:*** .** *:* ** *** * : ** * * *:*.:* *** * :**:* ***:. :** :**.**:**. ::.****** ** *. :**:* . *: ** : : . .. : :. : ..* :::: : * . . ***.* ** *:*******:. *:. ********.*.:**:****: :: ::* **: :* :* * .*:*: :: *:.: :**. ***:::*..**.* : *****: .:** .** *. *:******.:* * .*. *: : ****:* .* *:.* *: .******: : :****************:*:::**:**************:**:*: :: **:.:*. .. : ", "identical_positions": 205, "similar_positions": 131, "identity": "40.35%" }, { "cls_id": "homologset.agr.HGNC:3529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91Y47-1", "uniprot_id": "FA11_MOUSE", "id": "Q91Y47-1", "name": "Coagulation factor XI", "aln": "MTSLHQVLYFIFFASVSSECVTKVFKDISFQGGDLSTVFTPSATYCRLVCTHHPRCLLFTFMAESSSDDPTKWFACILKDSVTEILPMVNMTGAISGYSFKQCPQQLSTCSKDVYVNLDMKGMNYNSSVVKNARECQERCTDDAHCQFFTYATGYFPSVDHRKMCLLKYTRTGTPTTITKLNGVVSGFSLKSCGLSNLACIRDIFPNTVLADLNIDSVVAPDAFVCRRICTHHPTCLFFTFFSQAWPKESQRHLCLLKTSESGLPSTRITKSHALSGFSLQHCRHSVPVFCHPSFYNDTDFLGEELDIVDVKGQETCQKTCTNNARCQFFTYYPSHRLCNERNRRGRCYLKLSSNGSPTRILHGRGGISGYSLRLCKMDNVCTTKINPRVVGGAASVHGEWPWQVTLHIS---QGHLCGGSIIGNQWILTAAHCFSGIETPKKLRVYGGIVNQSEINEGTAFFRVQEMIIHDQYTTAESGYDIALLKLESAMNYTDFQRPICLPSKGDRNAVHTECWVTGWGYTALRGEVQSTLQKAKVPLVSNEECQTRYRRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKYNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEKTQTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4I9-1", "uniprot_id": "A0A0G2K4I9_RAT", "id": "A0A0G2K4I9-1", "name": "", "aln": "MTSLQQVLYFIFFASVSSECITKVFKDISFQGGDLSTVFTPSATYCQLVCTHHPRCLLFTFMAESSSDDPTKWFACILKDSLTETLPMVHMTGAVSGYSFKQCPQQLSACSKNVYVNLDMKGMNYNSSAVKNARECQERCTNDAHCQFFTYATGHFPSVDHRKMCLLKYTQMGTPTSITKLDSVVSGFSLKSCGLSNLACIRDIFPNTVLADLNIDSVLAPDAFVCRRICTHHPTCLFFTFFTQAWPKESQRHLCLLKTSESGFPSTRITKSNALSGFSLQHCRHSIPVFCHPNFYNDTDFLGEELDIVDVKGKESCQKMCSDNVRCQFFTYYPSRGSCSE--RKGRCYLKLSSNGSPTRILHGRGGISGYTLRLCKMDNVCTTKIRPRVFGGAASVHGEWPWQVTLHTT---QGHLCGGSIIGNRWILTAAHCFSGTETPKTLRVYGGIVNQSEINEDTTFFRVQEMIIHDQYTSAESGFDIALLKLEPAMNYTD--------------------------------EVQSTLQKAKVPLVSNEECQTRYRKHKITNKVICAGYKEGGKDTCKGDSGGPLSCKHNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEKTQSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03951-1", "uniprot_id": "FA11_HUMAN", "id": "P03951-1", "name": "Coagulation factor XI", "aln": "MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNE--GKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * **::**:*:***.**:*:::** .*:***::*******.**::***:********* ***.*:***:**:*:****:** ** *: *.*:********.:*:*:*.*::**:*****:*****..*.*:*******:*.**:****** ***::**::****:*: **** ****: **********.***************:** *****:******* ******* *******:* *******:**********:*****.**:******** ****:*****..**:************ .*.:*:*** *:: .******* *:: *.* :*:************:***********:******** *****.**:.**:***:********** : * **********:********* * *:** ****.**:*****:*.*:** ***:******. ****:********.::**** ::*.******:***:*****.*** ****:*:*****:*****:************:* **************.*:*********.:**********: ", "identical_positions": 444, "similar_positions": 110, "identity": "70.81%" }, { "cls_id": "homologset.agr.HGNC:3530", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80YC5-1", "uniprot_id": "FA12_MOUSE", "id": "Q80YC5-1", "name": "Coagulation factor XII", "aln": "MTALLFLGSLLMSLDLTLSAPPWKDSKKFKDAPDGPTVVLTVDGRLCHFPFQYHRQLHHKCIHKRRPGSRPWCATTPNFDEDQQWGYCLEPKKVKDHCSKHNPCHKGGTCINTPNGPHCLCPEHLTGKHCQKEKCFEPQLLKFFHENELWFRTGPGGVARCECKGSEAHCKPVASQACSINPCLNGGSCLLVEDHPLCRCPTGYTGYFCDLDLWATCYEGRGLSYRGQAGTTQSGAPCQRWTVEATYRNMTEKQALSWGLGHHAFCRNPDNDTRPWCFVWSGDRLSWDYCGLEQCQTPTFAPLVVPES----------QEESPSQAPSLSHAPNDSTD--------HQTSLSKTNTMGCGQRFRKGLSSFMRVVGGLVALPGSHPYIAALYWGNNFCAGSLIAPCWVLTAAHCLQNRPAPEELTVVLGQDRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLALLRLQESKTNSCAILSPHVQPVCLPSGAAPPSETVLCEVAGWGHQFEGAEEYSTFLQEAQVPFIALDRCSNSNVHGDAILPGMLCAGFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYTDVANYLAWIQKHIAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTE0-1", "uniprot_id": "FA12_RAT", "id": "D3ZTE0-1", "name": "Coagulation factor XII", "aln": "MTALLFLGSLLMSLDLTLSAPPWK-SKEFKDGAGDPSVVLTVDGKLCHFPFQYHRRLYHKCIHKGQPGSRPWCATTPNFDEDQQWGYCLEPKKVKDHCSKHSPCHKGGTCVNTPNGPHCLCPEHLTGKHCQREKCFESQLLKFFHENEIWFRTGPGGVARCQCKGPQAVCKLLTSQVCRVNPCLNGGTCLLVEDHRLCHCPAGYAGPFCDLDLKATCYEDRGLSYRGQAKTTLSGAPCQRWASEATYRNMTETQALSWGLGHHAFCRNPDNDTRPWCYVWSGDRLSWDYCDLEQCQMPTLTSPVSPES----------HDMLKPRPPILQSSPRDSTR--------NQNVVSRTSTVVCGQRFRKRLSSLRRVVGGLVALPGSHPYIAALYWGDSFCAGSLIDPCWVLTAAHCLQKRPAPEELTVVLGQDRHNQSCERCQTLAVHSYRLHEGFSSKTYQHDLALLRLR-GRKNSCAILSPHVQPVCLPSSAAPPSETVLCEVAGWGHQFEGAEEYATFLQEAQVPFISLDRCSSSNVHGDAILPGMLCAGFLEGGADACQGDSGGPLVCDEGVTERQLTLRGVISWGSGCGDRNKPGVYTDVANYLDWIQEHTAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00748-1", "uniprot_id": "FA12_HUMAN", "id": "P00748-1", "name": "Coagulation factor XII", "aln": "MRALLLLGFLLVSLESTLSIPPWEAPKEHKYKAEEHTVVLTVTGEPCHFPFQYHRQLYHKCTHKGRPGPQPWCATTPNFDQDQRWGYCLEPKKVKDHCSKHSPCQKGGTCVNMPSGPHCLCPQHLTGNHCQKEKCFEPQLLRFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQACRTNPCLHGGRCLEVEGHRLCHCPVGYTGAFCDVDTKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRNVTAEQARNWGLGGHAFCRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQTPTQAAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIREHTVS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***:** **:**: *** ***: .*:.* . :***** *. *********:*:*** ** :**.:**********:**:*****************.**:*****:* *.*******:****:***:*****.***:***:**:*:** ..****:***.:* *: ::**.* ****:** ** **.* **:**.**:* ***:* *:**:.******* * ** ****** *: ******:* ** .**** ********** ****:* . *****:**.* *** ** :. * * : * .*...* : :::...: ****:** ***: ********* *:**********..******* ************.*****:*******:*:*:*** ******:******.**. :**********: . .***:***:********.** ****.**:**************::*********::*:*** .:***.:**************:*************:: .:*::***:*:******************** ** **::* . ", "identical_positions": 407, "similar_positions": 112, "identity": "66.18%" }, { "cls_id": "homologset.agr.HGNC:3531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08619-1", "uniprot_id": "F13A_RAT", "id": "O08619-1", "name": "Coagulation factor XIII A chain", "aln": "--MSDTPATTFGGRGA-IPPNNS-NAAGVDLPT-EDLQGLVPRGVSLKDYLNVTAVHLFKERWDSNKIVHHTDKFD----NNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVTEL------QSGKWGAKVIMNEDRSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTQRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDIGGIFHGDFNDIKSRSWSYGQFEDGILDACLFVMDKA-EMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNVYAYGIPPSAWTGSVDILLEYRS-SETPVRYGQCWVLAGVFNTFLRCLGIPARVITNYSSAHDNDANLQMDIFLEEDGSVSFKLTKDSVWNYHCWNEAWMTRPDLPVGFG----GWQAVDSTPQENSDGMYRCGPASVQAVKHGHVCFQFDAPFVLGEVNSDLVYITAKKDGT-HVVENVDATHIGKLIVTKEIGGDGMQDITDTYKFQEGQEEERLALETALMYGAKKTLNTEGMVKSSSDVDMNFDVEN-AVLGKDFRVTITFQNNS-SNLYTILAYLSGNITFYTGVSKKEFKTESFEVTLDPLSLEKKEVLIRAGEYMSYLLEQGLLHFFVTARINETRVVLAKQKAIVLTIPKVTIKVRGTAMVG-SDMVVTVEFTNPLKETLKNVWLHLEGPGVMRPKRKMFREIRPNATVQWEEVCQPWVSGHRKLNASMTSDSLRHVYGELDLQIRRRPTV----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH61-1", "uniprot_id": "F13A_MOUSE", "id": "Q8BH61-1", "name": "Coagulation factor XIII A chain", "aln": "--MSDTPASTFGGRRA-VPPNNS-NAAEVDLPT-EELQGLVPRGVNLKDYLNVTAVHLFKERWDSNKIDHHTDKYD----NNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVKEL------QSGKWGAKVIMNEDRSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTRRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDIGVIFYGDFKDIKSRSWSYGQFEDGILDTCLYVMDKA-EMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNVYAYGIPPSAWTGSVDILLEYRS-SETPVRYGQCWVFAGVFNTFLRCLGIPARVITNYFSAHDNDANLQMDIFLEEDGNVSSKLTKDSVWNYHCWNEAWMTRPDLPVGFG----GWQAVDSTPQENSDGMYRCGPASVQAVKHGHVCFQFDAPFVFAEVNSDLVYITAKQDGT-HVVEAVDATHIGKLIVTKQIGGDGMQDITDTYKFQEGQEEERLALETALMYGAKKTLNTEGVVKSRSDVTMNFDVEN-AVLGKDFKVTITFQNNS-SNLYTILAYLSGNITFYTGVSKKEFKKESFEETLDPFSSKKKEVLVRAGEYMSHLLEQGFLHFFVTARINESRDVLAKQKSIILTIPKITIKVRGAAMVG-SDMVVTVEFTNPLKETLQNVWIHLDGPGVMRPKRKVFREIRPNTTVQWEEVCRPWVSGHRKLIASMTSDSLRHVYGELDLQIQRRPTM----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00488-1", "uniprot_id": "F13A_HUMAN", "id": "P00488-1", "name": "Coagulation factor XIII A chain", "aln": "--MSETSRTAFGGRRA-VPPNNS-NAAEDDLPT-VELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYE----NNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSEL------QSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRA-QMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRS-SENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFG----GWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGT-HVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVEN-AVLGKDFKLSITFRNNS-HNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVG-SDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPSM----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC84-1", "uniprot_id": "F1QC84_DANRE", "id": "F1QC84-1", "name": "", "aln": "MALPSHLPWPWGSQRARIAFAIS-NALEVSLPECESLPGVMPRGP-LPQTLSVQSLDMHIT---ENKQAHNTSMYK----NSSLIVRRNKEFLIDILFDRPFDETQDTVQLEFMIGSVPDENKGTYITVSFGSVK------TESSWRGRLLEKQGNSIRVGITPDVQSIIGRFSTFAVVVNETGKRRTEKNSATDFYVLFNPWDPSDQVYMPNEAERQEYVMNDVGTIYNGEINDISFRSWNYGQFEEGVLDACLFILDSG-KMPLMYRGNATEVARQASALMNSIDDNGVLAGNWTGDYSSGTAPTAWTGSAEILLKYASKGGAPVCFAQCWVFAGTLNTFFRALGIPARVITNYCSAHDNGGNIKANIMLNPDGSVNRKKTRDSIWNYHCWNEVFMKRFDLPDQYS----GWQVADCTPQETSDGLYRCGPTSVKCIKEGDLSYSFDSRFVFAEVNSDVVFHQFDKYGN-SKIVHVDTTYVGQLIVTKRPNTNGYIDITLNYKYPKGSAEDKRVMQLAERRGIPKRKYSP---LPDAGVQIDIKAET-IKIGENFTLTMNIKNQT-SQTSTVSLTVTGCAMYYTGLTSSTFKLENYSSTVDAWQTTPVTMKVQAAEYMSFLVEQSNLLFVVHGQVNETGKSVSAMRVINLRPPELMMKVTGVPQVG-RDLMVSVSFQNPYNFTLKNVQLRLDGAGLTPTKVKSYDQVAPGGSVQYTDTITPYSPGRKVLIGCLDCIPLSQITNQLEINVVN--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU2-1", "uniprot_id": "Q9VLU2_DROME", "id": "Q9VLU2-1", "name": "protein-glutamine gamma-glutamyltransferase", "aln": "MGQKLSCCQKCGDWKWCTSKDNEESTLRIRNANANYFTGIPQGDKTDGASSAVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLGDGSRSYPLP-LPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLGTVGRIPPAYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYK-TQKSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWRYNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQ-SRHAFSRYYLNDNFNDIEFDMELKDDIKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIEPRPEDLLQPNGSHRSSNIIRRRTDVIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . . .: . : *: . * .: *: *:*. : :. *:***.: * :.* *.* :. :* . . : :. .. . * .. .* . : .:..:: : : . . : .: . . *: . *:***** .* **: :. :*:***::* *: *. : : *. **** :*: .* ::. .: **:. .*:* **::*: **:*** *.* :: * .*: ****.:** :: . .* :.*** ::*.:.*: *.****:*::* * ****. ..: ::::: :.. * **:**** *** :* * ** ***..*.**** **.:** **:** .:*.*.: **. **:.***:* :: . . : *: :*:** ** *** .**. : . *:: .: * : .: :::. : :*:.* : :.. *:: . :: ***: .* :. ::. . : : ** . * .*. : : . .::::: : *.: ::: . *. :: * : : ** .*:: . ::*.*: . :: . :. * .*: : . : . * .: . . :: ", "identical_positions": 156, "similar_positions": 234, "identity": "20.03%" }, { "cls_id": "homologset.agr.HGNC:3534", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07968-1", "uniprot_id": "F13B_MOUSE", "id": "Q07968-1", "name": "Coagulation factor XIII B chain", "aln": "MMTLRHLPFILLLILSGELYAEEKQCDFPTVENGRIAQYYYTFKSFYFPMSVDKKLSFFCLAGYATESGKQEEQIRCTAEGWSPNPRCYKKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGGKDEEVVHCLSAGWSSQPSCRKEQETCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYY-LSGSDLIQCYNFG-WYPESPICEGRRNRCPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLCENGKWTEPPKCIEEKEKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECVENIENCKPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSPPVCLEPCTIDVDHMNRNNIQLKWKYEGKILHGDLIDFVCKQGYNLSPSIPLSEISAQCNRGDVRYPMCIRKESKGMCASPPVIRNGDIVSSAARTYENGSSVEYRCFDNHFLQG----SQNVYCVDGVWTTPPSCLEPCTLSFVEMDKNYLQLKWNFDNRPLILHGEYIEFMCKRDAYISETSIAGSVLRVQCDRGRLKYPKCTPRDRRLSFQEALRTRRQMEKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05160-1", "uniprot_id": "F13B_HUMAN", "id": "P05160-1", "name": "Coagulation factor XIII B chain", "aln": "-MRLKNLTFIIILIISGELYAEEKPCGFPHVENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEGWSPEPRCFKKCTKPDLSNGYISDVKLLYKIQENMRYGCASGYKTTGGKDEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYGWSLTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYY-LSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGKWTEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGKWTLPPECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEG----SREAYCLDGMWTTPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFICRGDTYPAELYITGSILRMQCDRGQLKYPRCIPRQSTLSYQEPLRT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A945-1", "uniprot_id": "A0AB13A945_DANRE", "id": "A0AB13A945-1", "name": "", "aln": "MKNFKIFLFLLLTIMDVPTNAEEVTCDEHQLIN------------------------VYILMGHPGVSAP--------------------------------------YKPGHILVFRCTDGNMMMYG--HRSIECLSNGKWDNP----------------------------------------YPKCG----VAMCPIN-------------TPVQNLKFERFPDIEGPIKPGHWMTFSCTEPWMKLKGQNEITCLVNGEWSSAFPRCEET------------------------------TCAANLTVNMRSDVEGQPG-------------REISVKP-----------------GHTVTLSCVRGAQFQGQNKITCR------------------------------------------------------------SNGEWDAP----------------------------------------------------------------FPKCVG----GICGPPPNVDNADTIYMQKTEYSSGERVEYRCFDKYTMDDRPSYSSYMTCQDAEWTGKIYCLKPCSVTLDTMNEKGIKVKYGPPRKLFSPHKDQILFACLRENERMKGNSK-----QICNDGTMTLPECV---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *::: *:. *** *. : * .: * *:. *. ** . : : *:.* * .. :.*** * .:* *. * . * :.:: :: * :: . : *. : * * * : *.*.: * * * * . * ** * *: :: :: : * : . :* *..** * * ::*.. ***. .:* *.:* :* * *:* .** : :. : *..*. *******:: ::. * * *. ** **:**:::: *::: : :*:. .: * : * * * : : *: * :. *.* ", "identical_positions": 87, "similar_positions": 102, "identity": "12.89%" }, { "cls_id": "homologset.agr.HGNC:3535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18292-1", "uniprot_id": "THRB_RAT", "id": "P18292-1", "name": "Prothrombin", "aln": "MLHVR-GLGLPGCLALAALAS-------------LVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDS---VRKPRET----FMDCLEGRCAMDLGLNYHGNVSVTHTGIECQLWRSRYPHRPDINSTTHPGADLKENFCRNPDSSTSGPWCYTTDPTVRREECSIPVCGQEGRTTVKMTPRSRGSKENLSPPLGECLLERGRLYQGNLAVTTLGSPCLAWDSLPTKTLSKYQNFDPEVKLVQNFCRNPDRDEEGAWCFVAQQPG---FEYCSLNYCDEAVGEEN-----HDGDESIAGRTTDAEFHTFFDERTFGLGEADCGLRPLFEKKSLTDKTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYIHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLQAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPYNHRWYQMGIVSWGEGCDRNGKYGFYTHVFRLKRWMQKVIDQHR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19221-1", "uniprot_id": "THRB_MOUSE", "id": "P19221-1", "name": "Prothrombin", "aln": "MSHVR-GLGLPGCLALAALVS-------------LVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDS---VRKPRET----FMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGD--FEYCNLNYCEEAVGEEN-----YDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRLKRWIQKVIDQFG-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00734-1", "uniprot_id": "THRB_HUMAN", "id": "P00734-1", "name": "Prothrombin", "aln": "MAHVR-GLQLPGCLALAALCS-------------LVHSQHVFLAPQQARSLLQRVRRANT-FLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACET---ARTPRDK----LAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQD-QVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGD--FGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAN5-1", "uniprot_id": "E7FAN5_DANRE", "id": "E7FAN5-1", "name": "Prothrombin", "aln": "MLQVFSGLQAQSLSRMGAKLAPLLLFLIFGQVFHLTLCHNVFIDSKEASQIIR-AKRANT-VFEELKPGNLERECVEEICDHEEAREVFERVDKTEIFWAKYLGCEGTTLSRTPQNINSLRICATTEGDCFINIGAKYAGKVSVTKSGKACQYWKSNFPHKIDEFNVTQ--LKLPENFCRNPDKHKDGPWCFTRDPTVRRETCNVPKCGEA----VVPPPKAPTAKPEQRHVISKCLPGNGETYTGELFVTLGLHTCLQWSSAEVQALIKKKELLPQVQLVKNHCRNPDGDMEGPWCYIKAASGNITIDYCDLELCDAPLDKFVE-------EGGGRERTTLDQRKAFFNPRSFGNGELDCGERPLFEKINKADKNEKELLMSYTGSRIVGGDEAEVASAPWQVMLYKRSPQELLCGASLISDEWILTAAHCILYPPWNKNFTINDIIVRLGKHSRTKYERGIEKIVAIDEIIVHPKYNWKENLNRDIALLHMKKPVVFTSEIHPVCLPTKSIAKNLMFAGYKGRVTGWGNLRESWTSNPTN-LPTVLQQIHLPIVDQSICRNSTSVIITDNMFCAGYQPDDSKRGDACEGDSGGPFVMKSPSDNRWYQIGIVSWGEGCDRDGKYGFYTHLFRMRRWMKKVIEKTDSGDDE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* ** . :.* : *. .::**: .::* .::: .:***: .:**:: ********** *.:*** *.:* *::***** *: *.*:: : ** * .:* :* * *.:*::* ** *:*.:**: : ..*: .* ********. . ****:* ******: *.:* **: * .*:: :. : : :*: .*. * *.* ** .** * * .::* * ::: . *:**:*.***** * ** **:: .* : **.*: *: .: : : . **: : ::**: ::** ** *** ****** . *..*:*** ** ..*** * :** . :******:::**************.*:******:*****:**** **::**:******:***.:*** :::* :**:***:***:*****:::**** *:. ******* :. . .*: *************:*:**:* : *:*** ::****::.:*: ** : *********:: :: ******************* ::****:***********.********:**:::*::***:: ", "identical_positions": 307, "similar_positions": 168, "identity": "47.16%" }, { "cls_id": "homologset.agr.HGNC:3537", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26824-1", "uniprot_id": "PAR1_RAT", "id": "P26824-1", "name": "Proteinase-activated receptor 1", "aln": "MGPRRLLLVAVGLSLCGPLLSSRVPMRQPESERMYATPYATPNPRSFFLRNPSEDTFEQFPLGDEEE--KNESIPLEGRAVYLNKSRFPPMPPPPFISEDASGYLTSPWLTLFIPSVYTFVFIVSLPLNILAIAVFVFRMKVKKPAVVYMLHLAMADVLFVSVLPFKISYYFSGTDWQFGSGMCRFATAACYCNMYASIMLMTVISIDRFLAVVYPIQSLSWRTLGRANFTCVVIWVMAIMGVVPLLLKEQTTQVPGLNITTCHDVLNETLLHGFYSYYFSAFSAIFFLVPLIISTVCYTSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIVCFGPTNVLLIVHYLLLSDSPGTETAYFAYLLCVCVTSVASCIDPLIYYYASSECQKHLYSILCCRESSDSNSCNSTGQLMPSKMDTCSSHLNNSIYKKLLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30558-1", "uniprot_id": "PAR1_MOUSE", "id": "P30558-1", "name": "Proteinase-activated receptor 1", "aln": "MGPRRLLIVALGLSLCGPLLSSRVPMSQPESERTDAT----VNPRSFFLRNPSENTFELVPLGDEEEEEKNESVLLEGRAVYLNISLPPHTPPPPFISEDASGYLTSPWLTLFMPSVYTIVFIVSLPLNVLAIAVFVLRMKVKKPAVVYMLHLAMADVLFVSVLPFKISYYFSGTDWQFGSGMCRFATAAFYGNMYASIMLMTVISIDRFLAVVYPIQSLSWRTLGRANFTCVVIWVMAIMGVVPLLLKEQTTRVPGLNITTCHDVLSENLMQGFYSYYFSAFSAIFFLVPLIVSTVCYTSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIVCFGPTNVLLIVHYLFLSDSPGTEAAYFAYLLCVCVSSVSCCIDPLIYYYASSECQRHLYSILCCKESSDPNSCNSTGQLMPSKMDTCSSHLNNSIYKKLLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25116-1", "uniprot_id": "PAR1_HUMAN", "id": "P25116-1", "name": "Proteinase-activated receptor 1", "aln": "MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNAT----LDPRSFLLRNPND---KYEPFWEDEE--KNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:** :********:*. :***: ** :****:****.: : *: ::** **** * * * :* * *.************.*****:***** **:******::**.**:::*************** *******************:****** :***.*** * ******:****************:***********.***:.**.:** *********** :*************.*.*:.*:*:********:**:****:*****.********************************:**********.** :**.:. **:***********:*::.***************:::******:****..* **:****.********:**********:", "identical_positions": 322, "similar_positions": 67, "identity": "74.19%" }, { "cls_id": "homologset.agr.HGNC:3538", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63645-1", "uniprot_id": "PAR2_RAT", "id": "Q63645-1", "name": "Proteinase-activated receptor 2", "aln": "-MRSLSLAWLLGGITLLAASASCNRTVN-APGPN-SKGRSLIGRLDTPPPITGKGAPVEPGFSVDEFSASVLTGKLTTVFLPVIYIIVFVIGLPSNGMALWVFFFRTKKKHPAVIYMANLALADLLSVIWFPLKISYHLHGNDWTYGDALCKVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKRANIAVGVSLAIWLLIFLVTIPLYVMRQTIYIPALNITTCHDV----------LPEEVLVGDMFSYFLSLAIGVFLFPALLTASAYVLMIKTLRSSAMDEHSEKKRRRAIRLIITVLSMYFICFAPSNVLLVVHYFLIKSQRQSHVYALYLVALCLSTLNSCIDPFVYYFVSKDFRDQARNALLCRSVRTVKRMQISLTSNKFSRKSSSYSSSSTSVKTSY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55086-1", "uniprot_id": "PAR2_MOUSE", "id": "P55086-1", "name": "Proteinase-activated receptor 2", "aln": "-MRSLSLAWLLGGITLLAASVSCSRTENLAPGRNNSKGRSLIGRLETQPPITGKGVPVEPGFSIDEFSASILTGKLTTVFLPVVYIIVFVIGLPSNGMALWIFLFRTKKKHPAVIYMANLALADLLSVIWFPLKISYHLHGNNWVYGEALCKVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHPRKKANIAVGVSLAIWLLIFLVTIPLYVMKQTIYIPALNITTCHDV----------LPEEVLVGDMFNYFLSLAIGVFLFPALLTASAYVLMIKTLRSSAMDEHSEKKRQRAIRLIITVLAMYFICFAPSNLLLVVHYFLIKTQRQSHVYALYLVALCLSTLNSCIDPFVYYFVSKDFRDHARNALLCRSVRTVNRMQISLSSNKFSRKSGSYSSSSTSVKTSY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55085-1", "uniprot_id": "PAR2_HUMAN", "id": "P55085-1", "name": "Proteinase-activated receptor 2", "aln": "-MRSPSAAWLLGAAILLAASLSCSGTIQ-GTNRS-SKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDV----------LPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IRY7-1", "uniprot_id": "I3IRY7_DANRE", "id": "I3IRY7-1", "name": "", "aln": "MAVSESYRILLFLACVIFASA--------QPGTG--KGRSLVVIQNDAGHMF-----------VDQIARETLQSSLTTVFMPIIYIIVFVVGLPTNAMAIYVLLFRSKKVHPAAIYMGNLALADLMFVIWTPLKIAYHLKGNNWTYGEEMCKVSVGFFYGNMYCSILFITCLSVQRYWVCAHPLTQQRRDNRLAIIISVCVWVFIGVSTTPLYLYNQTVQLQDLNITTCHDVNIITKKSFDNHNAFLDVQEPYYYFMVMAGLVFFVPMVVIIMAYVLLLRSLGNSSVKGSAGKSRKRAVILIVTVLITFLVCFIPSNVMLVVHYSLLRNNSFNASYGFYLTALCIASLNSCLDPFIYYYVSDDFREEVKNTLQCRSSRTVERMRVSFSSMKYSKRTNTYTSSSGNTETSTC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ** :: ** .. . *****: : : :*::: . * ..*****:*::* ****:***:*.**:::::**:** ***.***.*******: *** ****:**::**:* **: :*:* :*************:********** .:*: : *: .:*: :*:.:*::* : * ***: .**: : ********* : * : : **: :* **:.* .: ****::: * .*::. : *.*:**: **:*** :::** ***::***** *::.: . *.:*:.***:::****:***:**:**.***:..:*:* *** ***::*::*::* *.*:::.:*:*** ..:** ", "identical_positions": 178, "similar_positions": 121, "identity": "43.31%" }, { "cls_id": "homologset.agr.HGNC:3539", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08675-1", "uniprot_id": "PAR3_MOUSE", "id": "O08675-1", "name": "Proteinase-activated receptor 3", "aln": "--MKILILVAAGLLFLPVTVCQSGIN-VSDNSAKPTLTIKSFNGGPQNTFEEFPLSDIEGWTGATTTIKAECPEDSISTLHVNNATIGYLRSSLSTQVIPAIYILLFVVGVPANIVTLWKLSLRTKSISLVIFHTNLAIADLLFCVTLPFKIAYHLNGNNWVFGEVTCRITTVVFYGNMYCAILILTCMGINRYLATAHPFTYQKLPKRSFSMLMCGMVWVMVFLYMLPFVILKQEYHLVHSEITTCHDVVDACESPSSFRFYYFVSLAFFGFLIPFVIIIFCYTTLIHKLKSKDRIWLGYIKAVLLILVIFTICFAPTNIILVIHHANYYYHNTDSLYFMYLIALCLGSLNSCLDPFLYFVMSKVVDQLNP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920E1-1", "uniprot_id": "PAR3_RAT", "id": "Q920E1-1", "name": "Proteinase-activated receptor 3", "aln": "MEMKVLILVGVRLLFLPTTVCQSGMKHVSDNSA---LTAESFNGN-EHSFEEFPLSDIEGWTGATTTIKAKCPEESITTLHVNNATMGYLRSSLSTKVIPAIYILVFVIGVPANIVTLWKLSSRTKSICLVIFHTNLAIADLLFCVTLPFKIAYHLNGNDWVFGEVMCRVTTVAFYGNMYCAILILTCMGINRYLATVHPFTYRKLPKRNFTLLMCGVVWVMVVLYMLPLAILKQEYHLVQPGITTCHDVHDTCESPLPFQFYYFVSLAFFGFLIPFVVSVFCYTTLIHKLNAQDRKWLRYIKAVLLILVIFTICFAPTNIILIIHHANYYYSNTDSLYFMYLIALCLGSLNSCLDPFLYFIMSKIVDQLTS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00254-1", "uniprot_id": "PAR3_HUMAN", "id": "O00254-1", "name": "Proteinase-activated receptor 3", "aln": "--MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQR2-1", "uniprot_id": "F1QQR2_DANRE", "id": "F1QQR2-1", "name": "", "aln": "--MRRVFVPLLLMLIFEDSLQDPASKYSRINTSNYPLNPKTFTGTIESNASQLSNS-----------------SQTQPVINVSANVINHTAGIISTRIIPFAYILAILIGIPSNVFVLACLSGK-KVLSSGILYFSLALSDLLLLFSLTFRVHYHLNNSDWIFGELACKLVTACFYGNIYCSIHAHMCISVMRYFAVVHPFLYRTMRKRFCAIWMSLTIWVVFSIAMAPEFVVQQSFHVSGQELVTCHDIQPYEEASYQALIPYRLSLICIGFVFPSLVIAFIYGSIIYHLNRSSQDWKRYIKASTLVFVIFLVCFAPCNLLLFAHYVKLYTQRQYELYAYYRVAVCLCSFHSCLDPFLSYLLTKTSTSQVKFRSFSSIPLKALSTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ::. :*:: :. :.. : * : * ::* * . .::. * .:: . ::*. .:.: . :**::** *:* :::*:*:* ..* * : : :. ::: .**::*:*: .:*.*:: ****..:*:***: *: .*. ****:**:* *:.: **:* .*** *: : *: :: . :*. . : * * :::*.::: :.****: *:. : * :** :**::* :: : * ::* *: .: * *:** *::*** :**** *::*. *:.: * . ** * :*:** *::******* ::::* ", "identical_positions": 100, "similar_positions": 130, "identity": "25.84%" }, { "cls_id": "homologset.agr.HGNC:3540", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88634-1", "uniprot_id": "PAR4_MOUSE", "id": "O88634-1", "name": "Proteinase-activated receptor 4", "aln": "-MCWPLLYPLVLGLSISLAEGIQTPSIYDDVESTRGSHEGPLGPTVELKEPKSSDKPNPRGYPGKFCANDSDTLELPASSQALLLGWVPTRLVPALYGLVVAVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLAYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGQRLTTGLCLVAWLSAATLALPLTLHRQTFRLAGSDRMLCHDALPLTEQTSHWRPAFICLAVLGCFVPLLAMGLCYGATLRALAANGQRYSHALRLTALVLFSAVASFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRA-MLCRQPEASSSSQASREAGSRGTAICSSTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920E0-1", "uniprot_id": "PAR4_RAT", "id": "Q920E0-1", "name": "Proteinase-activated receptor 4", "aln": "-MCWPLLYPLMLGFSISPAE-CQTPSIYDDVESTREGQEASLRPTVELNESKSPDKPNPRGFPGKPCANNSDTLELPASSEALLLGWVPTRLVPAIYGLVVVVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLVYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHSLRARALRGQRLTTILCLVAWLSAATLVLPLTFHRQTFLLAGSDRMLCHDALPLAEQTSHWRPAFICLAVLGCFVPLLAMVLCYGATLRALAANGQRYSHAVRLTALVLFSAVAAFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRA-MLCRQLKASSSSQASREAGSRGTAICSSTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RI0-1", "uniprot_id": "PAR4_HUMAN", "id": "Q96RI0-1", "name": "Proteinase-activated receptor 4", "aln": "MWGRLLLWPLVLGFSLSGGT--QTPSVYDESGSTGGG-----------DDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**:**:*:* . ****:**: ** . .:.... * ***:**: ***:******* **.**************:****:.***************:.******:******.*******.****:.****************:*****************************.********:**: **:.*** **:*.****::**** ** ***:******** *:***:*** ***:****:***** *******::***.*:**.**:****:** **** *.***:**:****:***.******************************* ***:**** :: *. : :*:** *.**** . ** * ", "identical_positions": 281, "similar_positions": 64, "identity": "70.6%" }, { "cls_id": "homologset.agr.HGNC:35406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3USZ2-1", "uniprot_id": "UBFL1_MOUSE", "id": "Q3USZ2-1", "name": "Upstream-binding factor 1-like protein 1", "aln": "-------MTSLDNQGLWSEKDILKLLECMEHNIPSDDSREFKKSQADLNWSKVAFGLFSGEMCKQKWMEISYNLRKFRTLTELVQEAKFSFTKKTHKNKILTEHPDRPKRPLTAYLRFYKEQRAKYCQMYPKYSNAQLTKILAEKYRQLPAEIKQRYIMDFKKEKEDFQKKMRQFKKRHP-VSGHPKKSVVPQSHPTKVPTKSQGDIKNVKSLVKTESPRTVSSDMKFQGEPRKPPMNAYHKFHQESWSSPELRHLSFRKRWVEISRRWHQVPENEKEHYSNQVKRLQKQYRVKLDLWLKRLSPEEYAAYKEAKATCGKRKNMSMSGGRSSKFGRTE--QSSSEKGLQIKPGEVEELLDPGTDSSGTIQGHHDGAQSSRQDFTDDSEEDDSSTSSDSSSTDEDD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y0B7-1", "uniprot_id": "A0A8I5Y0B7_RAT", "id": "A0A8I5Y0B7-1", "name": "HMG box domain-containing protein", "aln": "-------MASLDNKSLWSEIDILKLLECMKKNITSDDSRDFKASQADLDWNNIAFGRFSGKMCKQKWMEISCKLRKFRTLTELVLEAKELWTR-AHKNNTIKHNPDRPKRPLTAYLRFYREHRAKYCQMYPRYTNAQLTKVLAKEYRQLPAEAKERYVQDFKKEKQAFQEKMAQLKKNHP-FSGHPKKSGVPRSHQTKDSKKSQGDMKTVKPLLNTEIPKTFSLAMQFQGEPRKPPMTAYHKFHQDSWSSPELRHLSFKERWVEISRLWHQVPEEMKEHYNRQAVELQKQYWMKLDLWLKGLSPEECAAYKKARATWGKGKIKRMSGGRSPKFGQTEDLQSASEKGLEAKPGEVEELLDWRTNSSETNIGHHGDFQASMQDMTDDSEDESSSNASDSSSTDEDD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CB48-1", "uniprot_id": "UBFL6_HUMAN", "id": "P0CB48-1", "name": "Putative upstream-binding factor 1-like protein 6", "aln": "MPAKDIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCRLKWLEISCSLRKFSTLKKLVLEAKKCVKN-TNKSQKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTD---QFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHYKSQAELLQKEYKVELDLWLKTLSPEDYAAYKES--TYAKGKNMAMMGGPAPSLKQTDP-QSSSAKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEDNRKKDGEEEESSNSLDCSSGEDMEVDV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:. **: ***:*****::*:. **. *. :*:.::*.::** ***:**: **:*** .**** **.:** *** .. ::*.: .:** *** ****:**::*: .:*.**** . ::**:*:::*::** : *:::: **:***: *::*: ::::.** .. : *** : : ** .* * ::: *:.* :*: . ::*:***:****..*:****:**** **:***:::* ***.* *:::*:. *:**. *. ***:* ::****** ****: ****:: * .* * * ** :..: :*: **:* ***: ** : * *::* * : . :: ..*.*::.**.: *.** :: : ", "identical_positions": 160, "similar_positions": 135, "identity": "39.31%" }, { "cls_id": "homologset.agr.HGNC:35409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ANL3-1", "uniprot_id": "A0A8I6ANL3_RAT", "id": "A0A8I6ANL3-1", "name": "", "aln": "--MPALLLIGTVALLASTAGPVGARPSND---------------TSAVAPGPLPALLAHLRRLTGALAGGGSAAGANANATKTSPAGGTGAAARAPPP-----AELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRAGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHREINVPRALVDILRHQAGPATRPDRARSSSLTPGLGGPESMAPRTPKNLYNTMKPSNLD-----------------WRAMPPPSPSLHYSTLSCS------------------RSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEA---YLKRRHLEMP--------------------RGTLPLHALRR-------PGTGGGYRMDGWGGPEELGLAPAPNPRRVMSQEHLLGDGGRASRYEFTLPRARLVSQEHLLLSSP--EALRQSREHLLSPPR-----------SPALPPDPTTRASLAASHSNLLLGPGGPPTPLHGLPP-SGLHAHHHH----ALHGSPQPAWMSDAGGGGG-----TLARRPPFQ--RQGTLEQLQFIPG-----HHLPQHLRTASKNEVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3Q5-1", "uniprot_id": "SHSA7_MOUSE", "id": "Q8C3Q5-1", "name": "Protein shisa-7", "aln": "--MPALLLLGTVALLASAAGPAGARPSND---------------TSSVAPGPLPALLAHLRRLTGALAGGGSAAGTSANATKTSPASGTGAAARAPPP-----AELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRAGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHREINVPRALVDILRHQAGPATRPDRARSSSLTPGLGGPDSMAPRTPKNLYNTMKPSNLDNLHYNVNSPKHHAATLDWRAMPPPSPSLHYSTLSCS------------------RSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEA---YLKRRQLEMP--------------------RGTLPLHALRR-------PGTGGGYRMDGWGGPEELGLAPAPNPRRVMSQEHLLGDGSRASRYEFTLPRARLVSQEHLLLSSP--EALRQSREHLLSPPR-----------SPALPPDPTTRASLAASHSNLLLGPGGPPTPLHGLPP-SGLHAHHHH----ALHGSPQPAWMSDAGGGGG-----TLARRPPFQ--RQGTLEQLQFIPG-----HHLPQHLRTASKNEVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NL88-1", "uniprot_id": "SHSA7_HUMAN", "id": "A6NL88-1", "name": "Protein shisa-7", "aln": "--MPALLLL---VLLASSAGQARARPSNA---------------TSAEPAGPLPALLAHLRRLTGALTGGGGAASPGANGTRTGPAGGAGAAARAPPP-----AELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQAGPGTRPDRARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLD-----------------WRALPPPSPSLHYSTLSCS------------------RSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEA---YLKRRPLELP--------------------RGTLPLHALRR-------PGTGGGYRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRS-RYEFTLPRARLVSQEHLLLSSP--EALRQSREHLLSPPR-----------SPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPPSSLHAHHHH----ALHGSPQPAWMSDAGGGGG-----TLARRPPFQ--RQGTLEQLQFIPG-----HHLPQHLRTASKNEVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6I1-1", "uniprot_id": "A0A8M2B6I1_DANRE", "id": "A0A8M2B6I1-1", "name": "", "aln": "MPPAAILLFFLFGPLVSAVTLTSERSSVNGGPVLLLLRGRGRKAPPPDVQGKQAAAMAAEPEAAEIPPRPLPQIMLPLNVTDYALKPPLGAAQVAPPPQRLVDVDVCQGYYDVMGQFDNTFNCTKGTYVYCCGTCHYRFCCEHQRQRLDQDSCTNYRSPDWAVTAGPITQPP---------------------VRHDPDFDPLQQQSNNTAYVIGGVISFTMAVAIGVKVAFHKLSRRPR-NRDINMPRALVDILRHQSSPVQQGERNNSTVLTTATSSEGTLG-RQAKNFYAPVLQSKDNRTG--KHSFGQTGSSPKHTATIERVPRMNNTQLASTGTLLSSKHNNSGFHPSFSHSFHNLAQLPPSYETVMKPELNRYSSLKRLEKNLDDYSGYYTSKRRPNNAPPSFHSSQHHLPWGGDFTLGARGTLPLNTSRTRIHMPSTTSTPNPYPLPQTQYNPTFDTMSKP-PRRVMSQDQLLALGEGNTLSRLSKNQQHLYYKPMTTSKSSNTQTLRKSHERLLVSPDRLEERMMGDYGGMVPTMSRLSHHQKAQSQQNVCVTPSLDRHHMIKMNSHPTSGREQDHPAIPSGHGTGTLGWGEIHGSGGGPGTMGHNARRMAFATKRQNTIEQLHFLPGGGGGGGGAGQALRTGSKNEVTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:**: *.*:. . *.* ... * .* :* . : . * * . *** **** .::*:********:* ****:.*:* :*************:: ** * **:** :* **.*. *:: . ... : ...****: *****::**.:*.**** * ** ** :*:**:***********:.* : :* .*: **.. .. :: * .**:* .: .: : * * :: : *:.: :*****::******:.:*.*********** :: * : *** : * ******:: * ..* . * : :. . * *******::**. * .:: : :* : .*. ::**:*:*:** .* . . . . :: . * *:.*: : *. : : . . .:.* : **: .* . *.*** *** .* **.*:***:*:** * ***.*******", "identical_positions": 200, "similar_positions": 143, "identity": "30.4%" }, { "cls_id": "homologset.agr.HGNC:3541", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42533-1", "uniprot_id": "TF_RAT", "id": "P42533-1", "name": "Tissue factor", "aln": "MAIPMRPRL----LAALAPTFLGFLLLQVAVGAGTPP---GKAFNLTWISTDFKTILEWQPKPTNYTYTVQIS--DRSRNWKYKCTGTTDTECDLTDEIVKDVNWTYEARVLSVPWRNSTHGKETLFGTHGEEPPFTNARKFLPYRDTKIGQPVIQKYEQGGTKLKVTVKDSFTLVRKNGTFLTLRQVFGNDLGYILTYRKDSSTGRKTNTTHTNEFLID-VEKGVSYCFFAQAVIFSRKTNHKS-PESITKCTEQW-KSVLGET-LIIVGAVVFLVTVFIILLTISLCKRRKNRAGQKRK-NTPSRLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20352-1", "uniprot_id": "TF_MOUSE", "id": "P20352-1", "name": "Tissue factor", "aln": "MAILVRPRL----LAALAPTFLGCLLLQVIAGAGIP----EKAFNLTWISTDFKTILEWQPKPTNYTYTVQIS--DRSRNWKNKCFSTTDTECDLTDEIVKDVTWAYEAKVLSVPRRNSVHGDGDQLVIHGEEPPFTNAPKFLPYRDTNLGQPVIQQFEQDGRKLNVVVKDSLTLVRKNGTFLTLRQVFGKDLGYIITYRKGSSTGKKTNITNTNEFSID-VEEGVSYCFFVQAMIFSRKTNQNS-PGSSTVCTEQW-KSFLGET-LIIVGAVVLLATIFIILLSISLCKRRKNRAGQKGK-NTPSRLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13726-1", "uniprot_id": "TF_HUMAN", "id": "P13726-1", "name": "Tissue factor", "aln": "METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTN--TVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQIS--TKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYP-----AGNVESTGSAG-EPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLID-VDKGENYCFSVQAVIPSRTVNRKS-TDSPVECMGQE-KGEFREI-FYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UY88-1", "uniprot_id": "B0UY88_DANRE", "id": "B0UY88-1", "name": "Tissue factor", "aln": "MGIQT---------VICSALFLAFLALVNGSPASMDVGKLTKATNVSWTSYNFKTILSWGPKPVNYTYTVEFSRTNRDKQRNPHCIRSTETECDLTNDL--DINEVYSAEVLSEP--------LPSMNIDQVEPPYSRSKIFRPYDDTLIGRPQFTLTVSIDKKLVLTIQDPITALHKDNRSLNIRDIFKKNLKYKVAYSKAGSTGKKIKVVEESRAEFNRLDEDQSYCFSVAAYIPNRKGDKRLGEWSLPKCSPQESKSLFEEYGLAVIGGAALATLAFVIAVIVLIVVCCKRAQKQTPTAKETIV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . :*. : :. * *::* * :*****.* ***.* .***::* :. : : :* :*:******::: *:. .* *.*:* * ** : .: * ** :* :*:* : . . *: :.::* * ::::. *.:*::* ::* * : * * .*:*:* .. .. :: :::. .*** . * * .*. ::. * * * *. : * : ::*...: . ::* : : : * *. . : . ", "identical_positions": 70, "similar_positions": 95, "identity": "22.65%" }, { "cls_id": "homologset.agr.HGNC:35410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22978-1", "uniprot_id": "CG445_DROME", "id": "P22978-1", "name": "Rhodanese domain-containing protein CG4456", "aln": "-------------------------------------------------------------MATYEQVKDVPNH--PDVYLIDVRRKEELQQTGFIPASINIPLDELDKALNLDGSAFKNKYGRSKPEKQ-SPIIFTCRSGNRVLEAEKIAKSQGYSNVVIYKGSWNEWAQKEGL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCD9-1", "uniprot_id": "Q9VCD9_DROME", "id": "Q9VCD9-1", "name": "Rhodanese domain-containing protein", "aln": "------------MMMRHCMMALRVARSQIPFSTARNTQSNLLQRFYSQAP--------QIGIVDYDVVKKLPSE--PQKLLIDVREPEELKETGQIPASINIPLGVVSQELAASEQLFKSKYGREKPKPE-TEIIFHCKIGKRSLKAAEAAAALGFKNVKNYQGSWLDWAEREGLPK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG33-1", "uniprot_id": "Q9VG33_DROME", "id": "Q9VG33-1", "name": "Sulfurtransferase", "aln": "-------------------------------------------------------------MATYEEVKDIPNH--PEKYLFDVRNESELKETGVLPASINIPLSELEKALNLPEEDFAQTYGRVKPAVD-AVLIFSCKAGGRAARAANLASTLGFTNAKAYAGSWTEWQAKQS-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E9PY03-1", "uniprot_id": "E9PY03_MOUSE", "id": "E9PY03-1", "name": "", "aln": "------------------MLRLAVLRHSHTSAAAGTMAG--------------------VPTVSFSELRSLVAS--GRARLFDVRSP-EEAAAGTIPGALNIPVSELEIALNMDPAAFQTLYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKQG-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFU3-1", "uniprot_id": "TSTD1_HUMAN", "id": "Q8NFU3-1", "name": "Thiosulfate:glutathione sulfurtransferase", "aln": "------------------------------------MAG--------------------APTVSLPELRSLLAS--GRARLFDVRSR-EEAAAGTIPGALNIPVSELESALQMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREWLEKES-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LEJ3-1", "uniprot_id": "A0ABK0LEJ3_RAT", "id": "A0ABK0LEJ3-1", "name": "Rhodanese domain-containing protein", "aln": "MEVPENPWDVRVRCLQVPWGGLFVERGAWGVAAGLKQPGRGVQRQVSCPPALKSFFSFPVPTVSFSELRQLLAS--GRARLFDVRSR-EEAAAGTIPGALNIPVSELEMALNMDPAAFQTSYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKEG-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8A5G0-1", "uniprot_id": "B8A5G0_DANRE", "id": "B8A5G0-1", "name": "", "aln": "------------------------------------MAS-------------------SDNDISYSDLKSILAK--GSAVLVDVRTN-EEVARGTIPGSIHIPVGNIGQDLSLDAAEFQSKFGVGKPPLDCTELVFFCQLGRRGAAATEKAKSLGFKNARNYAGAYKEWSEKEGK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08742-1", "uniprot_id": "RDL2_YEAST", "id": "Q08742-1", "name": "Thiosulfate sulfurtransferase RDL2, mitochondrial", "aln": "-----------------------MFKHSTGILSRTVSARSPTLVLRT-------FTTKAPKIYTFDQVRNLVEHPNDKKLLVDVREP-KEVKDYKMPTTINIPVNSAPGALGLPEKEFHKVFQFAKPPHD-KELIFLCAKGVRAKTAEELARSYGYENTGIYPGSITEWLAKGGADVKPKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12305-1", "uniprot_id": "RDL1_YEAST", "id": "Q12305-1", "name": "Thiosulfate:glutathione sulfurtransferase", "aln": "-----------------------MWKAVMNAWNGTESQSK---------------NVSNIQSYSFEDMKRIVGKHDPNVVLVDVREP-SEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDSA-KELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSHGGDKLDL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *.*** . :* ::::* : * ** ::* * * * * : * *: .. * *: :* : . ", "identical_positions": 19, "similar_positions": 21, "identity": "10.5%" }, { "cls_id": "homologset.agr.HGNC:35412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SQM0-1", "uniprot_id": "EMAL6_MOUSE", "id": "Q5SQM0-1", "name": "Echinoderm microtubule-associated protein-like 6", "aln": "MADRTAPRCQLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLALHPDKTLIATGQVGKEPYICIWNSYNVHTVSILKDVHTHGVACLAFDSDGQHLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRMVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLTLVRTIQGAHSAGIFSLYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVIVRERDKPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVSFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDVYAVAQRYKKIGECNKSLSFITHIDWSLDSKYLQTNDGAGERLFYKMPSGKPLTSKEEIKGIPWASWTCVRGPEVSGIWPKYTEVIDINSVDANYNSSVLVSGDDFGLVKLFKFPCLKKGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHSVFQWRFIPEAVSNGVLETTPQEGGADSYSEESDSDFSDVPELDSDIEQETQINYDRQVYKEDLPQLKQQSKEKNHAVPFLKREKAPEDSLKLQFIHGYRGYDCRNNLFYTQAGEVVYHIAAVAVVYNRQQHAQRLYLGHDDDILSLTIHPVKDYVATGQVGRDAAVHVWDTQTLKCLSLLKGHHQRGVCALDFSADGKCLVSVGLDDFHSVVFWDWKKGEKIATTRGHKDKIFVVKCNPQHADKLVTVGIKHIKFWQQAGGGFTSKRGSFGSAGKLETMMCVSYGRMEDLVFSGAATGDIFIWKDVLLLKTVKAHDGPVFAMYALDKGFVTGGKDGIVELWDDMFERCLKTYAIKRTALSTSSKGLLLEDNPSIRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMLSFHHRKEMISDIKFSKDTGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAKEQLFFEAPRGRKHTIRPSEAEKIEWDTWTCVLGPTCEGIWPAHSDVTDVNAANLTKDGSLLATGDDFGFVKLFSYPVKGQHARFKKYVGHSAHVTNVRWLHNDSVLLTVGGADTALMIWTREFVGTQESKLVDSEESDTDAEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSMEERPPVSRAAPQPEKLQKNNITKKKKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTTPSIHIWDAMTKHTLSMLRCFHTKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGTKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLYKKGVIGSMEAAKMQTMLSVAFGANNLTFTGAINGDVYVWKEHFLIRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLVECVRSVCRGKGKILVGTKDGEIIEVGEKSAASNILIDGHMEGEIWGLATHPSKDMFISASNDGTARIWDLADKKLLNKVNLGHAARCAAYSPDGEMVAIGMKNGEFVILLVNTLKVWGKKRDRKSAIQDIRISPDNRFLAVGSSEQTVDFYDLTQGTSLNRIGYCKDIPSFVIQMDFSADSKYIQVSTGAYKRQVHEVPLGKQVTEAMVVEKITWASWTSVLGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLLKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSSDDKYVVSTGGDDCSVFVWRCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ALD1-1", "uniprot_id": "A0A8I6ALD1_RAT", "id": "A0A8I6ALD1-1", "name": "", "aln": "MADRTAPRCQLRLEWVYGYRGHQCRNNLYYTASKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLALHPDKTLIATGQVGKEPYICIWDSYTVQTVSILKDVHTHGVACLAFDSDGQHLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRMVSCGVKHIKFWTLCGNSLTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLTLVRTIQGAHSAGIFSLYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVIVRERDKPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVSFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDVYAVAQRYKKIGECNKSLSFITHIDWSLDSKYLQTNDGAGERLFYKMPSGKPLTSKEEIKGIPWASWTCVRGPEVSGIWPKYAEVIDINSVDANYNSSVLVSGDDFGLVKLFKFPCLKRGAKFRKYVGHSAHVTSVRWSHDFQWVLSTGGADHAVFQWRFIPEAVSNGVSETTPQ-GGADSCSEESDSDVSDVPELDSDIEQETQINYDRQVYKEDLPQLKQQSKEKNHAVPFLKREKAPEDSLKLQFIHGYRGYDCRNNLFYTQAGEVVYHIAAVAVVYNRQQHTQRLYLGHDDDILSLTIHPVKDYVATGQVGRDAAVHVWDTQTLKCLSLLKGHHQRGVCALDFSADGKCLVSVGLDDCHSVVFWDWKKGEKIATTRGHKDKIFVVKCNPHHADKLVTVGIKHIKFWQQAGGGFTSKRGSFGSAGKLETMMCVSYGRMEDLVFSGAATGDIYIWKDVLLLKTVKAHDGPVFAMYALDKGFVTGGKDGIVELWDDMFERCLKTYAIKRAALSTSSKGLLLEDNPSIRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMLSFHHRKEMISDIRFSRDTGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAKEQLFFEAPRGRRHTIRPSETEKIEWDTWTCVLGHTCEGIWPAHSDVTDVNAASLTKDGSLLATGDDFGFVKLFSYPVKGQHARFKKYVGHSAHVTNVRWLHNDSVLLTVGGADTALMIWTREFVGTQESKLVDSEESDTDAEEDGGYDSDVAREKAIDYTTKIYAVSIRQMEGTKPHQQLKEVSMEERPPVSRAAPQPEKLQKNSITKKKKVIEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAATGVVQNLTTGGQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTTPSVHIWDAVTKHTLSMLRCSHSKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGTKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLYKKGVIGSMEAARMQTMLSVAFGANNLTFTGAINGDVYVWKEHFLIRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLVECVRSVCRGKGKILVGTKDGEIIEVGEKSAASNILIDGHMEGEIWGLATHPSKDMFISASNDGTARIWDLADKKLLNKVNLGHAARCAAYSPDGEMVAIGMKNGEFIILLVNSLKVWGKKRDRKSAIQDIRISPDNRFLAVGSSEHTVDFYDLTQGTSLNRIGYCKDIPSFVIQMDFSADSKYIQVSTGAYKRQVHEVPLGKQVTEAMVIEKITWASWTSVLGDEVIGIWPRNADKADVNCACVTHDGLNIVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSYDDKYVVSTGGDDCSVFVWRCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZMW3-1", "uniprot_id": "EMAL6_HUMAN", "id": "Q6ZMW3-1", "name": "Echinoderm microtubule-associated protein-like 6", "aln": "MADRTAPRCQLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLALHPDKTLVATGQVGKEPYICIWDSYNVQTVSLLKDVHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRVVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLNLVRTIQGAHSAGIFSMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVIVRERDKPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVAFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDVYAVAQRYKKIGECSKSLSFITHIDWSLDSKYLQTNDGAGERLFYRMPSGKPLTSKEEIKGIPWASWTCVKGPEVSGIWPKYTEVTDINSVDANYNSSVLVSGDDFGLVKLFKFPCLKRGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHSVFQWRFIPEGVSNGMLETAPQEGGADSYSEESDSDLSDVPELDSDIEQEAQINYDRQVYKEDLPQLKQQSKEKNHAVPFLKREKAPEDSLKLQFIHGYRGYDCRNNLFYTQAGEVVYHIAAVAVVYNRQQHSQRLYLGHDDDILSLTIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCALDFSADGKCLVSVGLDDFHSIVFWDWKKGEKIATTRGHKDKIFVVKCNPHHVDKLVTVGIKHIKFWQQAGGGFTSKRGTFGSVGKLETMMCVSYGRMEDLVFSGAATGDIFIWKDILLLKTVKAHDGPVFAMYALDKGFVTGGKDGIVELWDDMFERCLKTYAIKRSALSTSSKGLLLEDNPSIRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDKTLRIWELSAQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMISDIKFSKDTGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAREQLFFEAPRGKRHIIRPSEIEKIEWDTWTCVLGPTCEGIWPAHSDITDVNAASLTKDCSLLATGDDFGFVKLFSYPVKGQHARFKKYVGHSAHVTNVRWLHNDSVLLTVGGADTALMIWTREFVGTQESKLVDSEESDTDVEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVEERPPVSRAAPQPEKLQKNNITKKKKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTTPSIHIWDAMTKHTLSMLRCFHSKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLYKKGVIGSLGAAKMQTMLSVAFGANNLTFTGAINGDVYVWKDHFLIRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLVECVRSVCRGKGKILVGTKDGEIIEVGEKNAASNILIDGHMEGEIWGLATHPSKDLFISASNDGTARIWDLADKKLLNKVSLGHAARCAAYSPDGEMVAIGMKNGEFVILLVNSLKVWGKKRDRKSAIQDIRISPDNRFLAVGSSEHTVDFYDLTQGTNLNRIGYCKDIPSFVIQMDFSADGKYIQVSTGAYKRQVHEVPLGKQVTEAVVIEKITWASWTSVLGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSYDDKYVVSTGGDDCSVFVWRCL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************.******************************************:**************:**.*:***:*******************:*********************************************:****************:*******************************************.***************:*********************************************************************************************************************************:**************************************************************************.******************************:************************:***********:** ********************************:***************.******************:*********.****: **:** ***** *******.*************:*********************************************************************************:*********************************:****************:************************ **:****************************:*.**************************:***.***************************:****:**************************************************:************************************************************************************:**********************************************:************:**:******************************************************:**********::* ***** ************* ***********:******.**** **********************************************************************************.****************************:**************:*******************.******::***********************************:*:****:**.************************************:*****:********** *:**********************************:****************************************************: **:****************************:*******************************************************************************************.*************************:************************.**************************:*****:********************************:***********.**********************.**************************:*:************************************ ************:****************************** *********************", "identical_positions": 1873, "similar_positions": 72, "identity": "95.66%" }, { "cls_id": "homologset.agr.HGNC:35414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF30-1", "uniprot_id": "A0ABK0LF30_RAT", "id": "A0ABK0LF30-1", "name": "", "aln": "MKTNPAGAPLETCQTAGQGEKGYPVCQACGGASSLGSASESGSGLRPGPGVALDSGLGPGAIPGPGPGPGLGPSAVPGSGPQPSSVSVTGLRPGTTSGPNASLGPGLGTGSLPGPGARSGLRPGCDSVPAPAPQPGSGPVPQSGSGPVPQSGSGPVPQSGAGSVSQPGAGSVPQPVSELVTSPGAAPLPGLGLGPGTRRGSGTGSNPGESVRATVPALQQKTEAKHTQAPRQKVLVTGGGGYLGFSLGSSLAKKGASVILLDLRRPQWPLPSGTEFIQADVRDEEALYQAFQGVDCVFHVASYGMSGAEKLQKREIESINVGGTKLVINVCVRRRVPRLVYTSTVNVTFGGKPIEQGNEDSIPYFPLDKHMDHYSRTKAIADQLILMANGTPLLGGGTLRTCVLRPPGIYGPEEQKHLPRVASHIKKRLFMFRFGDRRTHMNWVHVQNLVQAHMRAAEGLTLAKGYVASGQAYYIHDGESVNLFEWMAPLFEKLGYSQPWIQVPTSCVYLTAAVMEFLHLALRPICTISPLLTRSEVL-SMTVTHTFQIAKARAQLGYAPDKFSFADAVERYVQATTPQPCCCTVLTLLRLLLLLLLLLGLLGLALYFLGLQPLQAVVERL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LI11-1", "uniprot_id": "A0A140LI11_MOUSE", "id": "A0A140LI11-1", "name": "", "aln": "MKTNPAGSPLETCQTAGQVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQKTQAKHTQAPRQKVLVTGGGGYLGFSLGSSLAKRGTSVILLDLRRPQWPLPSGTEFVQADVRDEEALYQAFQGVDCVFHVASYGMSGAEKLQKQEIESINVGGTKLVINVCVRRRVPRLVYTSTVNVTFGGKPIEQGNEESIPYFPLDKHMDHYSRTKAIADQLTLMANGTPLLGGGTLRTCVLRPPGIYGPEEQRHLPRVASHIKKRLFMFRFGDRKTRMNWVHVQNLVQAHMLAAEGLTMAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSCVYLTAAVMEYLHLALRPICTIPPLLTRSEVRGVVAVTHTFQIAKARTQLGYAPDKFSFADAVERYVQATTPQPRCCIVLTLLRLLLMLLLLFALLGLALYFLGLQPLQAVVERL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKP2-1", "uniprot_id": "D42E2_HUMAN", "id": "A6NKP2-1", "name": "Putative short-chain dehydrogenase/reductase family 42E member 2", "aln": "MKSNPPRSSLEACKAAGQAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVR-SVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVERL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RIK4-1", "uniprot_id": "A0A8M1RIK4_DANRE", "id": "A0A8M1RIK4-1", "name": "", "aln": "MKENRSSCQMEQLPCACLLDCHRQTHSRSAAATIPLRHRANG------------------------------------------------------------------------------------------------------------------------------------------------------------------AVGALCSSPNCVVSDRLEDSGKGRFGTGRVLVTGGAGYFGYRLGRALARQGAAVVLLDLHQPPWDIPDGAVFQQIDIRDYDTLYKISAGVDVIFHTASYGMSGPEQLRKKQIESVNVGGTNNVINVCAERGISRLIYTSTVNVAFAGRPIEDGDEDSVPCVPLDMHIDHYSRTKAIAERMVLAANRRSTKGGGLLHTCVLRPSGIYGPEERRHLHRVMVNVERRFFSFCFGDPNAKMNWVHVDNLVTAHVLAAQALTAEKAFVASGQAYFINDGESVNVFEWLTPLFERLGYGRPLIHLPVSLVYSAAILMERLHVALRPIVEIPLLLTRNEVR-NIAVSHTFKIEKAQRDLGFSPQRFSLKDSVDQYLQS---RPVRSASSFSAQHLMLLLLICGFFALFMHCLA-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . . :* * :: :: : :******.**:*: ** **: *::*:*** ::* * :. : * * *:** ::**: *** :**.*******.*:*:*.:***:*****: **:**..* :.**:*******:*.*:***:*:*:*:* .*** *:**********::: * ** . *** *:******.*******::** ** ::::*:* * *** .::******.*** **: **:.** *.:*******:*:******:***::****:***.:* *::*.* ** :* :** **:***** :. ****.** ::*:***:* **: :**::*::* : *:*: *:*: :* . : *: ***: .::.* :: *. ", "identical_positions": 206, "similar_positions": 115, "identity": "33.17%" }, { "cls_id": "homologset.agr.HGNC:35418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JN27-1", "uniprot_id": "TF2H2_RAT", "id": "A0JN27-1", "name": "General transcription factor IIH subunit 2", "aln": "-----------------------------------MDEEPERTK------------------------------RWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKTAKIRVSVIGLSAEVRVCTVLARET----GGTYHVILDETHYKELLARHVSPPPASSGSE-CSLIRMGFPQHTIASLSDQDAKPSFSMAHLDNNSTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYKGE--------RFCYGCQGEL-----------KDQHVYVCTVCRNVFCVDCDVFVHDSLHCCPGC-------------------VHKIPTQS------GV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIB4-1", "uniprot_id": "TF2H2_MOUSE", "id": "Q9JIB4-1", "name": "General transcription factor IIH subunit 2", "aln": "-----------------------------------MDEEPERTK------------------------------RWEGGYERTWEILKEDETGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKTAKIRVSVIGLSAEVRVCTVLARET----GGTYHVILDETHYKELLAHHVSPPPASSSSE-CSLIRMGFPQHTIASLSDQDAKPSFSMAHLDNNSTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEISLEEYKGE--------RFCYGCQGEL-----------KDQHVYVCTVCQNVFCVDCDVFVHDSLHCCPGC-------------------IHKIPTPS------GI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13888-1", "uniprot_id": "TF2H2_HUMAN", "id": "Q13888-1", "name": "General transcription factor IIH subunit 2", "aln": "-----------------------------------MDEEPERTK------------------------------RWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARET----GGTYHVILDESHYKELLTHHVSPPPASSSSE-CSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGN-TEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGE--------RFCYGCQGEL-----------KDQHVYVCAVCQNVFCVDCDVFVHDSLHCCPGC-------------------IHKIPAPS------GV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNP8-1", "uniprot_id": "Q9VNP8_DROME", "id": "Q9VNP8-1", "name": "General transcription factor IIH subunit", "aln": "----------------------------------MADDEQEDQKE----------------------------YRWETGYEKTWEAIKDDEDGMLDGAIAEIIQKAKRQRQAQKSKQNRLGMMRHMFVVLDCSESMSVPDLKPTRLRCTVKLLELFIEEFFDQNPISQLGLIALKAKRAEKVTELTGTSRVHLKALESLANVSLTSEPSLQNGLDLALKSLKVVPSHASREIVIIMGSLTTCDPVDINLTIDELKKEGIRCSVISLSAEIHVARYLTQQT----MGTFGAVLDDAHFRDQLMSQVDPPPAAKTQH-NSLIRMGFP-HTKNEVEGKDAPLSMCMCHIENLEEPSELTTTGHHCPQCNSKYCELPVECQSCGLTLVSAPHLARSYHHLFPVPNFEELPFEAMPASSSDLTSDVRECYGCAKALGQGV----DKVADKVVFRCGFCKQFFCVDCDIFIHDTLHACVGCNTIPGVDGLVYQQSSKSDQVDAHPGPSKQRGQCGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04673-1", "uniprot_id": "SSL1_YEAST", "id": "Q04673-1", "name": "General transcription and DNA repair factor IIH subunit SSL1", "aln": "MAPVVISESEEDEDRVAITRRTKRQVHFDGEGDDRVDQQQQQHSSSHRDRDKHVQRKKKKRLSNRNLQGSNGGYAWEDEIKRSWDLVKVDDEGDMASLVASIVEARKKRTAKKNITPYQRGIIRSLILTLDCSEAMLEKDLRPNRHAMIIQYAIDFVHEFFDQNPISQMGIIIMRNGLAQLVSQVSGNPQDHIDALKSIRKQEPKGNPSLQNALEMARGLLLPVPAHCTREVLIVFGSLSTTDPGDIHQTIDSLVSEKIRVKVLGLSAQVAICKELCKATNYGDESFYKILLDETHLKELFNEAVTPLPVNKINKGFTLVKMGFPTRIFEDT------PTFCSCH-------SKLVYGGYFCPNCHSKVCSLPTVCPCCDLMLILSTHLARSYHHLMPLKTFAEVPTTEKFRS--------EDCFSCQSRFPILKNHKNGKLLTSSRYRCEDCKQEFCVDCDVFIHEILHNCPGC--------------------ESKPVIT--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : . ** :::*: :* *: * : . : .*: *:: :: : *::* : :.:* *.:* **:*.* :: *:.*:********:*:* : *: :::::*..: *: :*:. . .:*** *.*.:* * :*.* :**::*::.**:* ** :* *. * ** .*:.***:: :. * : * . : :**::* :: : * * *. . .. :*::**** : . ::. .* . *. *:.**:*.:* *.**. * *.* *: :.*********:*: * *:. . . *:.* : . : * *:: ******:*:*: ** * ** . * : ", "identical_positions": 117, "similar_positions": 128, "identity": "22.94%" }, { "cls_id": "homologset.agr.HGNC:3542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K3W2-1", "uniprot_id": "A0A0G2K3W2_RAT", "id": "A0A0G2K3W2-1", "name": "Coagulation factor V", "aln": "MPLATGGRDLTKPLPTLGIEGKGGRVIQPPLGTGTLTAPNSFLVLQGVRTARSRDRALSTVSRGSARGRTRAMFLVCPRFFLLVVLGTRWAGWGSHQAEAAQLRQFYVAAQGILWNYHPESADPSLN-SIPSFKKIVYREYEPYFKKEKPRSSNSGLLGPTLYAEVGDTIKVHFRNKADKPLSIHPQGIRYSKFSEGASYLDHTSPAERKDDAVAAGEEYTYEWFIGEDSGPTPDDPPCLTHIYYSYENLTQDFNSGLIGPLLICKEGTLTEDGTQKMFDKQHVLLFAVFDESKSWSQSPALMYTVNGFVNRTMPDVTVCAYDHVSWHLIGMSSGPELFSIHFNGQVLEQNQHKVSTVTLVSATSTTANMTMSPEGKWIVSSLIPKHYQAGMQAYIDIKNCPKKTRSSKTLTREQRRHMKRWEYFIAAEEVIWNYAPVIPANMDKLYKSLHLDNFSNQIGKHYKKVIYREYKDETFTKRIENQSSRQSGILGPIIKAQVRDTLKIVFKNMASRPYSIYPHGVTFSPYEDGVNSSSTSG-SHTMIKPVQPGETFTYKWNILEFDEPTENDAQCLTRPYYSDVDVTRDIASGLIGLLLICKSRSLDQRGIQRVADMEQEVVFAMFDENKSWYIEDNINKFCENPDEVKRDDPKFYESNIMNTINGYVPESISTLGFCFDDAVQWHFCSVGTHDDILTVHFTGHSFIYGRRHEDTLTLFPMSGESVTVVMDNIGTWMLTTMSSNPRRRNLRLRFRDVKCNRNDDDDEDSYEIYQPLEPTSMTTRKIHDSVENDFGIENEDDDYQYELASTLGIRSFRKSLLNPKEDEFNLTALALENSSEFISLSTDGVVDSKSSR--NLSKITNNNLNDSQRTLSGSGATIAGILLGNLTGLGKNSVLNPSTEYHSSSYYENDMEDP-QSNITVVYLLPLGAKGSGSREQTKPKTIKTGRPHRMKHRFSWMKAPAGKTGRHSNPKN------------------TSSRMKSEEDIPSDLLLLKQKVASKLLNRQWHMASEKGSYEIIPANGENTDIDKLTNSPQNQNISTPWGASTSRINTTGKPSNLPTFSRFRHKSPHVRQEEESGDFKKRQLFIRTRKKKKNRKFALHSPLSPRGFYHPRREDHPPLLDRRLLNHSLLLHKSNETALSTDLNQTSPPVST--DRSLPDYNQNPSNDTEQMSSSLDLFQSVPPEEHSPTFPTQDPNQTHSTTDPSYRSSPPEPSQGIDYDLSHEFYSDDISQTS-----------FFPDQSQKSPLTSDDGQAIPSSDLNLFTISPELDQTIIYPDLDQLFLSPDDIQKTSSQDLGQVTLSPDENQETSSQDLGQVTLSPNENQETSSQDLGQVTLSPDDIQETSSQDLGQVTLSPDENQETSSPDLGQVPLTPDDNQKT-SPDLGQVLLSLDDKQKTYFLDPGQVPISSDQSWETSSTDLSLLTLSPKFGQTVISPDLDKMPLSSDNSQVTLSPDLSLLTLS---------PDFNEIILSPDIDQVTLSPDLIQTSPALNHRHKTSSADPGQASYPPDSGQSSPLPELNQTLPHPDLIHMQPPLLSPTPNDTSLSKTFNPLVVVGLSRVDGDDVEMIPSEELESIDEDYPEDDYVTYNDPYKTDTRANVNSSRNPDTIAAWYLRSFGGNKKFYYIAAEEISWDYSKFAPSEMDNEETDNTPKDTTYKKVVFRKYLDSTFTSRDPQGEYEEHLGILGPVIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKNYEDDSPKWFQEDDAVQPNSSYTYVWHATERAGPENPGSACRAWVYYSAVDVERDIHSGLIGPLLICRKGTLDRASNLPLDMREFVLLFMVFDEKKSWYYEK-SKGSWRIESPEAKNSHEFYAINGMIYNLPGLRMYEQEWVRLYLLNMGGPQDIHVVHFHGQILLDNRTKQHHLGVWPLLPGSFKTLEMKASKPGWWLLDTAVGENQIAGMQTPFLIIDKECKMPMGLSTGAISDSQIKASEYLTYWEPRLARLNNGGSYNAWSIEKSALDFPIKPWIQVDMEKEVVVTGIQTQGAKYYLKSCFTTEFQVAYSSDRTNWQIFRGNSMKSVMSFAGNSDASTIKENRFDPPIVARYIRIHPTKSYNRPTLRLELLGCEVNGCSTPLGLEDGRIQNKQITASSFKKSWWGSYWEPSLARLNAQGRVNAWQAKANNNKQWLQIDLLKIKKVTAIVTQGCKSLSSEMYVKSYSILYSDQGVSWKPYRQKSSMVDKIFEGNSNTKGHMKNFFNPPIISRFIRIIPKTWNQSIALRLELFGCDIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88783-1", "uniprot_id": "FA5_MOUSE", "id": "O88783-1", "name": "Coagulation factor V", "aln": "------------------------------------------------------------------------MLLVCPCFFLLVVLGTRWAGWGSHQAEAAQLRQFYVAAQGILWNYHPEPTDPSLN-SIPSFKKIVYREYEQYFKKEKPRSSNSGLLGPTLYAEVGDVIKVHFRNKADKPLSIHPQGIKYSKFSEGASYADHTFPAERKDDAVAPGEEYTYEWIVSEDSGPTPDDPPCLTHIYYSYENLTQDFNSGLIGPLLICKKGTLTEDGTQKMFDKQHVLLFAVFDESKSRSQSPSLMYTINGFVNKTMPDITVCAHDHVSWHLIGMSSGPELFSIHFNGQVLEQNQHKVSTVTLVSATSTTANMTMSPEGRWIVSSLIPKHYQAGMQAYIDIKNCPKKTRSPKTLTREQRRYMKRWEYFIAAEEVIWNYAPVIPANMDKIYRSQHLDNFSNQIGKHYKKVIYRQYEEETFTKRTDNPSIKQSGILGPVIRAQVRDTLKIVFKNMASRPYSIYPHGVTFSPYEDGINSSSTSG-SHTTIRPVQPGETFTYKWNILEFDEPTENDAQCLTRPYYSDVDVTRDIASGLIGLLLICKSRSLDQRGVQRVADIEQQAVFAVFDENKSWYIEDNINKFCENPDEVKRDDPKFYESNIMSTINGYVPESISTLGFCFDDTVQWHFCSVGTHDDILTIHFTGHSFIYGRRHEDTLTLFPMRGESVTVTMDNVGTWMLTTMNSNPKRRNLRLRFRDVKCNR-DYDNEDSYEIYEPPAPTSMTTRRIHDSLENEFGIDNEDDDYQYLLASSLGIRSFKNSSLNPEENEFNLTALALENSSEFISPSTDRVVDSNSSR--ILSKIINNNLKDFQRTLPGSGATVAGTLLRNLIGLDENFVLNSSTEHRSSSYHENDMENP-QSNITMVYLLPLGPKGSGNREQDKPKTIKTGRPHMMKHRFSWMKAPAGKTGRHSNPKN------------------SYSGMKSEEDIPSELIPLKQKITSKFLNRRWRVASEKGSYEIIAANGEDTDVDKLTNSPQNQNITVPRGESTSHTNTTRKPSDLPTFSGVGHKSPHVRQEEENSGFQKRQLFIRTRKKKKNKKLALHSPLSPRGFDPLRGHNHSPFPDRRLLNHSLLLHKSNETALSPDLNQTSPSMST--DRSLPDYNQYSKNDTEQMSSSLDLYQSVPAEEHSPTFPAQDPDQTHSTTDPSYRSSPPELSQGLDYDLSHDFYPDDIGLTS-----------FFPDQSQKSSFSSDDDQAIPSSDLSLFTISPELDQTIIYPDLDQLLLSPEDNQKTSSPDLGQVPLSPDDNQKTSSPDLGQVSLSPDDNQKTSSPDLGQVPLSLDDNQKTTSPDLGQVPLSPDDNQMITSPDLGQVPLSSDNQKTS-SPDLGQVPLFPEDNQ-NYFLDLSQVPLSSDQNQETSSTDL--LTLSPDFGQTVLSPDLDQLPLPSDNSQVTVSPDLSLLTLS---------PDFNEIILAPDLGQVTLSPDLIQTNPALNHGHKASSADPDQASYPPDSGQASSLPELNRTLPHPDLTHIPPPSPSPTLNNTSLSRKFNPLVVVGLSRVDGDDVEIVPSEEPERIDEDYAEDDFVTYNDPYRTDTRTDVNSSRNPDTIAAWYLRGHGGHKKFYYIAAEEITWNYAEFAQSEMDHEDTGHTPKDTTYKKVVFRKYLDSTFTSRDPRAEYEEHLGILGPVIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDESPEWFQEDDAVQPNSSYTYVWHATKRSGPENPGSACRAWAYYSAVNVERDIHSGLIGPLLICRKGTLHMERNLPMDMREFVLLFMVFDEKKSWYYEK-SKGSRRIESPEEKNAHKFYAINGMIYNLPGLRMYEQEWVRLHLLNMGGSRDIHVVHFHGQTLLDNRTKQHQLGVWPLLPGSFKTLEMKASKPGWWLLDTEVGENQVAGMQTPFLIIDKECKMPMGLSTGVISDSQIKASEYLTYWEPRLARLNNAGSYNAWSIEKTALDFPIKPWIQVDMQKEVVVTGIQTQGAKHYLKSCFTTEFQVAYSSDQTNWQIFRGKSGKSVMYFTGNSDGSTIKENRLDPPIVARYIRIHPTKSYNRPTLRLELQGCEVNGCSTPLGLEDGRIQDKQITASSFKKSWWGDYWEPSLARLNAQGRVNAWQAKANNNKQWLQVDLLKIKKVTAIVTQGCKSLSSEMYVKSYSIQYSDQGVAWKPYRQKSSMVDKIFEGNSNTKGHMKNFFNPPIISRFIRIIPKTWNQSIALRLELFGCDIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12259-1", "uniprot_id": "FA5_HUMAN", "id": "P12259-1", "name": "Coagulation factor V", "aln": "------------------------------------------------------------------------MFPGCPRLWVLVVLGTSWVGWGSQGTEAAQLRQFYVAAQGISWSYRPEPTNSSLNLSVTSFKKIVYREYEPYFKKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGASYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGLIGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWSQSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQNHHKVSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKITREQRRHMKRWEYFIAAEEVIWDYAPVIPANMDKKYRSQHLDNFSNQIGKHYKKVMYTQYEDESFTKHTVNPNMKEDGILGPIIRAQVRDTLKIVFKNMASRPYSIYPHGVTFSPYEDEVNSSFTSGRNNTMIRAVQPGETYTYKWNILEFDEPTENDAQCLTRPYYSDVDIMRDIASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNINKFCENPDEVKRDDPKFYESNIMSTINGYVPESITTLGFCFDDTVQWHFCSVGTQNEILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTSMNSSPRSKKLRLKFRDVKCIP--DDDEDSYEIFEPPESTVMATRKMHDRLEPEDEESDADYDYQNRLAAALGIRSFRNSSLNQEEEEFNLTALALENGTEFVSSNTDIIVGSNYSSPSNISKFTVNNLAEPQKAPSHQQATTAGSPLRHLIGK--NSVLNSSTAEHSSPYSEDPIEDPLQPDVTGIRLLSLGAGEFKSQEHAKHKGPKVERDQAAKHRFSWMKLLAHKVGRHLSQDTGSPSGMRPWEDLPSQDTGSPSRMRPWKDPPSDLLLLKQSNSSKILVGRWHLASEKGSYEIIQDTDEDTAVNNWLISPQ--NASRAWGESTPLANKPGKQSGHPKFPRVRHKSLQVRQDGGKSRLKKSQFLIKTRKKKK-EKHTHHAPLSPRTFHPLRSEAYNTFSERRLK-HSLVLHKSNETSLPTDLNQTLPSMDFGWIASLPDHNQNSSNDTGQASCPPGLYQTVPPEEHYQTFPIQDPDQMHSTSDPSHRSSSPELSEMLEYDRSHKSFPTDISQMSPSSEHEVWQTVISPDLSQVT-LSPELSQTNLSPDLSHTTLSPELIQRNLSPALGQMPISPDLSHTTLSPDLSHTTLSLDLSQTNLSPELSQTNLSPALGQMPLSPDLSHTTLSLDFSQTNLSPELSHMTLSPELSQTNLSPALGQMPISPDLSHTTLSLDFSQTNLSPELSQTNLSPALGQMPLSPDPSHTTLSLDLSQTNLSPELSQTNLSPDLSEMPLFADLSQIPLTPDLDQMTLSPDLGETDLSPNFGQMSLSPDLSQVTLSPDISDTTLLPDLSQISPPPDLDQIFYPSESSQSLLLQEFNESFPYPDLGQMPSPS-SPTLNDTFLSKEFNPLVIVGLSKDGTDYIEIIPKEEVQSSEDDYAEIDYVPYDDPYKTDVRTNINSSRDPDNIAAWYLRSNNGNRRNYYIAAEEISWDYSEFVQRETDIEDSDDIPEDTTYKKVVFRKYLDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSWYYEKKSRSSWRLTSSEMKKSHEFHAINGMIYSLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQHQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRMPMGLSTGIISDSQIKASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGCDIY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** :::****** *.****: :*************** *.*:**.::.*** *:.*********** *******:*: ************** *****:**************:***:****** *** ***: *****.*.****** :.****** ************:*** :**************:*****.**** **** ************ ***.:****:**:** ****:****:**:****:*********************:****::*************:.***:**:*** *** ******************. *.:******:***************:*********** *:* ****************:* :*::*:***: * . ::.*****:*:********************************* :*** *** .:* *:.******:*****************************: ********************:**:**.**:**:.***:********:***************************.**********:********:**********:::***:**********:*********** ******.***:******:*.*.*: ::***:****** *:******::* .* *:**::** :* : .: * *** **::******::* ** :*:***********.:**:* .** :*.*: * :**: *** : *:: . . ** ** * :* * * ***.** :**.* *: :*:* *.::* : **.**. .:*: * * *. * : ******** * *.*** . .. : * *:. :* **:*: ***. :**:* :*::********** ..*:* ::: *** * : . * **. *.. * *. *.*. . *** :***: .. ::* *::*:****** .* : *:***** * * . : .: :*** ***:*******:*..***** *.:. ****:** ..*** * *.. .*:*:**.*** *** ***:* ***:***:***.** *: ::** **. :. **. * : ** ** : ::.: .*: *.**. *:**** * : * *.*: :**: :.* * **.:..** * .* . * :*.*..*** .* . * **.:..** * * . * :*.::.***: .* ** ***:*::.* .:.: * *:.*. * : .* . .*:*:*.* . * * ** .***.:.** :****.::** :* **:.::***. :*** *:*.:: *:**:.*******: :*. : : :...* .* **.:*.*: * *:*.::*:*** :: .* *** *:* **: *****:****: . * :*::*.** : ::**.* *:*.*:***:**.*:::****:**.*******. .*::: ********:*:*::*. * * *::.. *:******************.***:.***********:*************************************.***:**:**:**:***************:*:***.********.*****: *:*************:** *. *:*:**********.*********** *:.* *: *.* *::*:*:*******.****:*********:***:**.:********** **:* .***:**************************:* ***** *********:*::*:******** **********:* ***********.*******:** * :*. ********:***::*********:*****:**** *****:: *****:*:* :.** * ****.******::*********** **::********** ************:*:*:*::**************.**** ***********************::*******:***:****************:* **:*** ***** ************:*****:**************:*********************", "identical_positions": 1458, "similar_positions": 439, "identity": "63.23%" }, { "cls_id": "homologset.agr.HGNC:35422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8MQ27-1", "uniprot_id": "NEU1B_HUMAN", "id": "A8MQ27-1", "name": "E3 ubiquitin-protein ligase NEURL1B", "aln": "-----------------------------------------MGN-----------TVHRT--------LPDPSPPARLLATRPCCGP---GPERR----PVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLES-AFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQ-VVAKLGHLALGRAPGPPPADAAAAAIPCGPRERP------RPASSPAL-LEADLR--------------FHATRGPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVAR-AGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRG------GVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMT-----------------------FSVNQSSSASESS---------------------------------------------------------------------LVTAPSSPLSPPVSPVFSPP----------EPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQAR-ACCPICRRPIKDVIKIYRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0MW30-1", "uniprot_id": "NEU1B_MOUSE", "id": "Q0MW30-1", "name": "E3 ubiquitin-protein ligase NEURL1B", "aln": "-----------------------------------------MGN-----------TVHRT--------LPDSSPPARLLATRPCYGP---GPERR----AVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLES-TFADTLTPLRLGQARLSACPPPGSHDAANFDNNELENNQ-VVAKLGHLALGRP---------DAAVPCVARERP------RPASSPAL-LDAELR--------------FHATRGPDVSLSADRRLACAPRPDGGRTLVFSERPLRPGESLCVEVGRPGLAAPAAVAFGITSCDPGALRPSELPADPAALLDRKEYWVVAR-AGPVPSGGDALSFTLRPGGDVLLAVNGRPRGRLLCVDTSQALWAFFAVRG------GVAGQLRLLGTLQSSSETMTPSGSFSGSQDDSDSDMT-----------------------FGVNQSSSASESS---------------------------------------------------------------------LVTAPSSPLSPPVSPAFSAP----------EPTGSRNGECTVCFDSEVDTVIYTCGHMCLCHGCGLRLRRQAR-ACCPICRRPIKDVIKIYRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8QF54-1", "uniprot_id": "A0A2R8QF54_DANRE", "id": "A0A2R8QF54-1", "name": "E3 ubiquitin-protein ligase NEURL1B", "aln": "-----------------------------------------MGNNGSFVVFSTQDTVCKTRVQWQCSSLQDASLQHRSVASRQYCTVSTSGAERRTSAPPVSIESPRFHPHAKGKNIRLDAHLRRATRKNSFCNGITFSQRPVRLYEKVRLRLSGVHTGWSGALRFGFTTLDPGELSLTDIPKYACPDLVTRPGYWAKALPERLAMRDNVLAFWADRHGRVFYSINDGEPILFHCGLSVGCPVWAIIDIYGITQEVTLLES-TFAESVGASCLSTARLSAYLPQSNHDSANYSNNQLETNQAAAAKFATLQLSNY---------NQLIPCCSTSSTPSSSVQRPARSLSLPLDVDLH--------------FHPVRGPDVVLSNDRTVACTHFLDSSRTLMFSDRPVRVGETLYLEVGHLGLPYFGALLFGMTSCDPGTLSAGELPADPELLLDRKEYWVVYR-GFPVPTAGDVLSFTFLANGEVHHGVNGVARGRLLCVDSSQVLWAFFTLHG------AVN-RLRILGTVQASP-PTSPSVSQGSSPDDSDSDLA-----------------------FSVNRSSSASESS---------------------------------------------------------------------LVTAPSSPLSPPVSPSFSSSD---------APLSNKSSECTVCFDQEVDTVIYTCGHMCLCNDCGQRLKRQIN-ACCPICRRPIKDVIKTYRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29503-1", "uniprot_id": "NEUR_DROME", "id": "P29503-1", "name": "Protein neuralized", "aln": "MGLSDIPANYMQGSHPHLTLHPQQQHHQNQQHLQHLQQMQQLHNAMPTPAQQAAQVLAMESNELLMSTKDKLSSKKKMHLLKKIKKRFGLVRRSPSSCPGPNNLPPLQFHSVHGDNIRISRDGTLARRFESFCRAITFSARPVRINERICVKFAEISNNWNGGIRFGFTSNDPVTLEG-TLPKYACPDLTNRPGFWAKALHEQYCEKDNILYYYVNGAGDVIYGINNEEKGVILTGIDTRSLLWTVIDIYGNCTGIEFLDSRIYMYQQQPAAIPMATVPAQQQQMPQPAANASSALNSHHPHQQSRRSLPGHTAAIEHDLERHVMPSLQSLHLAGNGGSVASVEQAAIAHDLANGLPPLRYNANGRLIPVPFHNTKGRNVRLSQDRFVASRTESDFCQGYVFTARPIRIGEKLIVQVLKTEQMYVGALALGLTSCNPAMLQPNDLPNDSDFLLDRPEYWVVSKDIAAAPQRGDEIAFFVAPNGEVSISKNNGPAVVVMHVDQSLQLWAFLDVYGSTQSLRMFRQQLPNMVAYPSQPQVNVNASSSSACNAASTSRMLPMTESMSSLNAGATAKLLHHPSQLSVAQSTSTLASAGGVNGSRMISMPSNGDILQIQPNGGGTVLVVNLPPASSSHDINGQLAARPTATVTSSGVLAGACSSGTLISTTSSQYIEQPIANSTNNAANKWKDSLSDQQSTDSSAECTICYENPIDSVLYMCGHMCMCYDCAIEQWRGVGGGQCPLCRAVIRDVIRTYTT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: . * : : . .* . .:*.*:*:. . * * :***..:**: **:*: *:: ::: : .*.*.:*****: ** :. :********..***:***** *. . :*.:* ::.: * *:*.:*: * :: *: . :*::**:** : :*:* : . : * ..* : :** .. . : :: . : . : : * * ** .:* :* ** ** :*. * : :*: **:* **.* ::* : .*: :*:***:*. * ..:** *. **** ***** : ..* ** ::* . ..*:* . *. . :: ** : ****: : * . :* : : :.. : * ... * * : :.* :*:*: *: : *:.*. :. *:: . . ..***:*:: :*:*:* *****:* .*. . * . **:** *:***: * .", "identical_positions": 150, "similar_positions": 167, "identity": "19.87%" }, { "cls_id": "homologset.agr.HGNC:35426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B3GLJ3-1", "uniprot_id": "PATE3_MOUSE", "id": "B3GLJ3-1", "name": "Prostate and testis expressed protein 3", "aln": "MNKHFLLLFSLFYFIVEATSLKCVTCHLRTQSDHCRRGFGVCLAQKHEICMSLRIYFSGSLQLSYMVCQRFCKNLTYIFNNRTYTHKCCNSDFCNFRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B3GLJ2-1", "uniprot_id": "PATE3_HUMAN", "id": "B3GLJ2-1", "name": "Prostate and testis expressed protein 3", "aln": "MNKHFLFLFLLYCLIVAVTSLQCITCHLRTRTDRCRRGFGVCTAQKGEACMLLRIYQRNTLQISYMVCQKFCRDMTFDLRNRTYVHTCCNYNYCNFKL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:** *: :** .***:*:******::*:******** *** * ** **** .:**:******:**:::*: :.****.*.*** ::***:*", "identical_positions": 63, "similar_positions": 24, "identity": "64.29%" }, { "cls_id": "homologset.agr.HGNC:35427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y6V7-1", "uniprot_id": "A0A8I5Y6V7_RAT", "id": "A0A8I5Y6V7-1", "name": "UPAR/Ly6 domain-containing protein", "aln": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q09098-1", "uniprot_id": "PATE4_MOUSE", "id": "Q09098-1", "name": "Prostate and testis expressed protein 4", "aln": "MNSVTKISTLLI-------VILSFLCF----VEGLICNSCEKSRDSRCTMSQSRCVAKPGESCSTVSHFVGTKHVYSKQMCSPQCKEKQLNTGKKLIYIMCCEKNLCNSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C8F1-1", "uniprot_id": "PATE4_HUMAN", "id": "P0C8F1-1", "name": "Prostate and testis expressed protein 4", "aln": "---MRKMNTLLL-------VSLSFLYLK--EVMGLKCNTCIYTEGWKCMAGRGTCIAKENELCSTTAYFRGDKHMYSTHMCKYKCREEESSKRGLLRVTLCCDRNFCNVF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: . *.:* : .* **:* :.. .* . . * * . *** : : * :*: *.:** :*.*: . : :**.:*:** *", "identical_positions": 25, "similar_positions": 32, "identity": "22.73%" }, { "cls_id": "homologset.agr.HGNC:35428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61908-1", "uniprot_id": "CMC4_MOUSE", "id": "Q61908-1", "name": "Cx9C motif-containing protein 4", "aln": "-MP--QKDPCQK--QACE-IQKCLQANNYLESKCQA--VIQELRKCCARYPKG-----RSLVCSG---FEKE---------------EEEKLAMKSGSK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56277-1", "uniprot_id": "CMC4_HUMAN", "id": "P56277-1", "name": "Cx9C motif-containing protein 4", "aln": "-MP--QKDPCQK--QACE-IQKCLQANSYMESKCQA--VIQELRKCCAQYPKG-----RSVVCSG---FEKE---------------EEENLTRKSASK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IZJ0-1", "uniprot_id": "A0A0R4IZJ0_DANRE", "id": "A0A0R4IZJ0-1", "name": "", "aln": "-MS--QKDPCQK--QACA-IQKCLQANRYIESRCED--VIRAMKKCCELHTGE-----NSVCCSG---FAKE---------------NKP-TDPKT-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZN8-1", "uniprot_id": "B7YZN8_DROME", "id": "B7YZN8-1", "name": "Cx9C motif-containing protein 4", "aln": "-MSDTRKDPCKP--NACR-IQACLTKNHYQEDKCLD--VLEAMRQCCLKWHK------ESLCCSG---IDLEKT-------YLPDASKEKNATGKSNK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7A9-1", "uniprot_id": "CMC4_YEAST", "id": "Q3E7A9-1", "name": "Cx9C motif-containing protein 4, mitochondrial", "aln": "-MS----NPCQK--EACA-IQDCLLSHQYDDAKCAK--VIDQLYICCSKFYNDNGKDSRSPCCPLPSLLELK--------------MKQRKLTPGDS----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0G2K2W2-1", "uniprot_id": "A0A0G2K2W2_RAT", "id": "A0A0G2K2W2-1", "name": "Protein p13 MTCP-1", "aln": "MAREDTGAPPTRLWVHCEGVYRDEHQRTWVAAAEEDTATLKARVRRVPVPLGDASKPRDLLTSPLPLMWQLYPEGRYMDNKSRLWQIRRHSVVRGAQELLLQLLPET", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : . : .: .. .. ", "identical_positions": 2, "similar_positions": 9, "identity": "1.87%" }, { "cls_id": "homologset.agr.HGNC:3544", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3U6-1", "uniprot_id": "FA7_RAT", "id": "Q8K3U6-1", "name": "Coagulation factor VII", "aln": "MVPQTHGLLLLYFLLQLQGPLGA---------------------VVFITQEEAHGVLHRQRRANS-LLEELWSSSLERECNEERCSFEEAREIFKSPERTKQFWTIYSDGDQCASNPCQNGGTCQDHLKSYVCFCPLDFEGRNCEKNKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYVLQPDEVSCKPKVEYPCGRIPVVEKRNFSRPQGRIVGGYVCPKGECPWQAVLKFNEALLCGAVLLDTRWIVTAAHCFDKFGKLVNITVVLGEHDFSEKEGTEQVRLVEQVIMPNKYTRGRTDHDIALVRLHRPVTFTDYVVPLCLPERAFSENTLASIRFSRVSGWG-----QLLDRGATALELMVIEVPRLMTQDCLEHAKHSANTPRITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVKYMDSKLRVGISRVSLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70375-1", "uniprot_id": "FA7_MOUSE", "id": "P70375-1", "name": "Coagulation factor VII", "aln": "MVPQAHGLLLLCFLLQLQGPLGT---------------------AVFITQEEAHGVLHRQRRANS-LLEELWPGSLERECNEEQCSFEEAREIFKSPERTKQFWIVYSDGDQCASNPCQNGGTCQDHLKSYVCFCLLDFEGRNCEKSKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYTLQPDEVSCKPKVEYPCGRIPVVEKRNSSSRQGRIVGGNVCPKGECPWQAVLKINGLLLCGAVLLDARWIVTAAHCFDNIRYWGNITVVMGEHDFSEKDGDEQVRRVTQVIMPDKYIRGKINHDIALLRLHRPVTFTDYVVPLCLPEKSFSENTLARIRFSRVSGWG-----QLLDRGATALELMSIEVPRLMTQDCLEHAKHSSNTPKITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVRHMDSKLQVGVFRLPLL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08709-1", "uniprot_id": "FA7_HUMAN", "id": "P08709-1", "name": "Coagulation factor VII", "aln": "MVSQA--LRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANA-FLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWG-----QLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZT1-1", "uniprot_id": "A0A8N7UZT1_DANRE", "id": "A0A8N7UZT1-1", "name": "", "aln": "MRVGAAAVLLCVLTLRSTS-------------------------AVFLSKDEASALLQRFRRANSGFLEEMKAGNLERECVEEICDYEEAREVFEDDDRTKQFWLSYSNKEPCLTNPCRNNGTCVYLADSYYCLCSEGYEGKYCEKGLEETLKCQYVNGGCEQFC-DGSGARRSCSCAEGYALADDGTSCVSQVDYPCGKIPVQKN----TSQNQFLGGIHCPRGHCPWQVLIDYNGESVCGGALLEGPWLITAAHCVHQKDTR-FLKAVTGEHDLDVLDGSEEPYEVSAVFIHPNYDPETLDSDLALLRLRVPVQRSLYAVPICLPTPQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKGPASGTLQRLAVP--LLPAAQCGN-ANTTANMFCAGYTEGDHASCRGHDGSPLVTRYGETSFLTGVVSWGRGCGPPGYYWIYTKVENFLIWMDTVMKTNTEDKSEQIANVSTKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : * : * . **::::** .:*:* ****: :***: ...***** ** *.:*****:*:. :*** ** **: : * :.**:*.*:* .** *:* :**: **. :: * * **.*:*:* * *::*:* * *.* * * .** . *:****:**: :: *.:::** **:*.****.:: * :**..*:: *:::****..: : .* ****:. :* *: * *:: .* : *:**:**: ** : :.**:*** ::. * ** :**** : * * : ** . * : : .: .. * ****** :* : :*:*..*.* .*:* * :***:****.**.. *: :**:*.::: *: * :: . . . ", "identical_positions": 159, "similar_positions": 128, "identity": "33.33%" }, { "cls_id": "homologset.agr.HGNC:35445", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LN05-1", "uniprot_id": "A0ABK0LN05_RAT", "id": "A0ABK0LN05-1", "name": "", "aln": "MKTRARQQPHLLKGKKKWLLWALSGFLFLFSVTMTGCFLWQYYLPKLQNGSSKSEVPPAQVRMCPRLPELVPLAHPLPVLKEALEKVDGILRKAMLAPGLAAMSALVIHNDTVLWTGNFGRKNGSDPNSGTPNEHTMYRIASISKIFPVLMLYRLWEEGIVASLDDPLERYASTFSINNPLGTAQGPEAQDPMGEFEEMGSLPSPSPVTLRRMASQLSGLPRRLRGTSLLWKGSTQEALSLLKDDVLVADPGTRCHYSTLAFSLLAHVLAAHRAQGDYERWVSEQVLEPLGMSDTGFALTGAVRARLAAGFYGSGRSAPLYDLGWYRPSGQMYSTAADLARLAAALMGAGPRRLLRPDSLATLLAPLRTCTHGYFASETGTPWEFHERLGYRVARKDGDLDGYAASLALVPPLRLGFVLLLAGPRPPTHDLVADALDTLLPALERALRDAELVPAPPPRARPFAGFFTFANRTFYEVRASGPRGELRLRQFGPRLEALVPAAFRSLALRHVRGRVFQLHVAREFPCALPLADAWLSLEAQHGQLVRFYPLDRHGLAPGFDVPGLNTYGVLRLPRRPVFGSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "S4R213-1", "uniprot_id": "S4R213_MOUSE", "id": "S4R213-1", "name": "", "aln": "MKTRARQQPHLLKGKKKWFLWALSGFLFLLSATMTGCFLWQLYLPKLQTGSLKPEVPPAPVKMCPRHPELVPLAHPLPVLKEALEKVDGILRKAMLAPGLAAMSALVIHNDTVLWTGNFGRKNGSDPNSGTPNEYTMYRIASISKIFPVLMLYRLWEEGIVDSLDDPLERYASTFSINNPLGTAQGPGAQGPTGESEEMGSLPRPSPVTLRRMASQLSGLPRRLRGTSLLWRGSTQEALSLLKDDVLVADPGTRCHYSTLAFSLLAHVLAAHRAQGDYERWVSEQVLEPLGMSDTGFALTGTVRARLAAGFYGSGRSAPLYDLGWYRPSGQMYSTAADLARLAAALLGAGPRRLLRPDSLATLLAPLRACAHGYFASETGTPWEFHERRGYRVARKDGDLDGYAASLALVPPLRLGFVLLLAGPRPPTRDLVADALDTLLPALERALREAELAPAPPPRARPFAGFFTFANRTFYEVRAAGPRGELRLRQFGPRVEALVPAAFRSLALRHVRGRVFQLHVAREFPCALPLADAWLSLESQHGQLVRFYPLDRHGLAPGFDVPGLNTYGVLRLPRRPVFSSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MY62-1", "uniprot_id": "BLML_HUMAN", "id": "A8MY62-1", "name": "Beta-lactamase-like protein 1", "aln": "MKTQDGWWPNLLKVKKKWLLPAICSFFCLLSVVMTGCFLWQYHLPKLKTGSLGPEETSAPVRMCPRHPEPVPLAHPLPVLKEALEKVDQILRQAMSAPGVAAMSAVVIHNDTVLWTGNFGKKNGSDPASGAPNEYTMYRISSISKIFPVLMLYRLWEEGIVASLDDPLERYASTFTINNPLGLAS-AEQQGLMDGLEQVGPAPRPSPVTLRRMASQLSGLPRRLRSTSLLWKGSTQEALNLLKDDVLVVDPGTRCHYSTLAFSLLAHVLAAHTAQGDYQRWVSENVLEPLGMADTGFDLTPDVRARLAAGFYGSGRPAPLYDLGWYRPSGQMYSTAADLAKLAVALLGGGPRRLLRPDAAKTLLAPLLACPGAYFANETGTPWEFHAQRGYRVVRKDGDLDGYAATFSLVPPLRLGLVLLLAGPRPPGPDLVARAYDELLPALERALREAEPGPAPPPTAHPFAGYFTFANLTFYEVRA-GPAGELRLRQFGPRVEALVPPAFRTLALRHLHGRVFQLHVAHEFPCALPLGDAWLSLEAQHGQLVNFYPLDHHGLSPGFDVPGLNTYRVLRLRGKPVFKTQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: *:*** ****:* *:..*: *:*..******** :****:.** .* ..* *:**** ** ****************** ***:** ***:*****:**************:****** **:***:*****:******************** *************:****** *. . *. . *::*. * *********************.*****:*******.********.*********************** *****:*****:*******:**** ** **************.***********************:**.**:*.*********: ****** :*. .***.********* : ****.***********:::********:********** **** * * **********:** ***** *:****:***** ******* ** ***********:*****.***:*****::*********:********.*******:******.*****:***:*********** **** :*** :*", "identical_positions": 457, "similar_positions": 71, "identity": "78.66%" }, { "cls_id": "homologset.agr.HGNC:35454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TZW0-1", "uniprot_id": "ECSCR_MOUSE", "id": "Q3TZW0-1", "name": "Endothelial cell-specific chemotaxis regulator", "aln": "---------------------MRLGSAILGLLLLQGYSSQPTTTQTSQ--------------------EILQKSSQVSLVSNQPVTPRSSTMDKQSLSLPDLMSFQPQKHTLGPGTGTPERSSSSSSSSSSRRGEASLDATPSPETTSLQTKKMTILLTILPTPTSESVLTVAAFGVISFIVILVVVVIILVSVVSLRFKCRKNKESEDPQKPGSSGLSESCSTANGEKDSITLISMRNIN-----------------VNNSKGSMSAEKIL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G5C4-1", "uniprot_id": "A0A8I6G5C4_RAT", "id": "A0A8I6G5C4-1", "name": "", "aln": "MDREYTEEPATHPADLGTNGAMRLGSAILSLLLLQGYSSQPTTTQTSQGDRSSSEPGSSGLPLSTITPEILQKSSQASLASSQPVTPRSSTMDRHSLSLPDPMSFQTQRHT--PGTGAPE-----SSSSSSRRGESSLDATPSPGTSSLRTKEG----TILPTPTSESVLTVAAFGVISFIVILVVVVIVLVSVVSLRFKCRKNKESEDPQKPGSSGLSESCSTANGEKDSITLISMKNIN-----------------TNNSKGCTSAEKIL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q19T08-1", "uniprot_id": "ECSCR_HUMAN", "id": "Q19T08-1", "name": "Endothelial cell-specific chemotaxis regulator", "aln": "---------------MGTAGAMQLCWVILGFLLFRGHNSQPTMTQTSS----------------------SQGGLGGLSLTTEPVSSNPGYIPSSEANRPSHLSS-----TGTPGAGVPS-----SGRDGGTSRDTFQTVPPNSTTMSLSMRED---ATILPSPTSETVLTVAAFGVISFIVILVVVVIILVGVVSLRFKCRKSKESEDPQKPGSSGLSESCSTANGEKDSITLISMKNIN-----------------MNNGKQSLSAEKVL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58ID40-1", "uniprot_id": "A0AC58ID40_DANRE", "id": "A0AC58ID40-1", "name": "", "aln": "---------------MEKLLFFLIPLITFSSIISAGNDTNLTSPTPPSTVFSPTN---------SVNLTEAAQQIENSTTYDDDISNQTSKPTTVQFSRSTVTGESTSSSSFIRSTTPTTISKFYTDTSLNGVSASATKITEAISSTTVFSNISMSEATVTPSP-AESRLTLLAFGVMSLILILIVVMVILVAAVNLKGRCCRNTQQHESIKNRDSLVSDSNLTSNGEKENITLVSVRTINTEYNADSPQISSVHSTIVDNDDHELSRDQLISLGS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. :: * .:: * . ... : :: ... . . . . : .: . :. . . : . : :: . *: *:* :*: **: ****:*:*:**:**:::**..*.*: :* :..:..:. * .* :*:* *:****:.***:*::.** :*.. * :::: ", "identical_positions": 40, "similar_positions": 79, "identity": "14.49%" }, { "cls_id": "homologset.agr.HGNC:35458", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVA5-1", "uniprot_id": "D3ZVA5_RAT", "id": "D3ZVA5-1", "name": "", "aln": "MKPAG----------GRGGWS-----WGGGKGGGK------GGDTG-SGAKGGFG-TRTRGGGGGGRGRGRGGGGGGGGGGGGGGGGGGGDRQRRGGPGRNKNRRKKG-ITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVTE----NGE---KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVKKLQQENLKPQEQLTLEPYERDHAVVVGVYRPAPKSSSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WS3-1", "uniprot_id": "FBLL1_MOUSE", "id": "Q80WS3-1", "name": "RNA 2'-O-methyltransferase FBLL1", "aln": "MKPAG----------GRGGWG-----WGGGKGGSK------GGDTG-SGTKGGFG-ARTRGSSGGGRGRGRGGGG--------GGGGGGGDRQRRGGPGKNKNRRKKG-ITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVME----NGE---KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPPPKSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHQ2-1", "uniprot_id": "FBLL1_HUMAN", "id": "A6NHQ2-1", "name": "RNA 2'-O-methyltransferase FBLL1", "aln": "MKSAASSRGGGGGGRGGGGWGS----WGGGRGGGGGAGKGGGGDGGGQGGKGGFG-ARARGFGGGGRGRGRGGGD---------GKDRGGGGQRRGGVAKSKSRRRKGAMVVSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTE----GGV---KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPLPKSSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1V3-1", "uniprot_id": "FBRL_DROME", "id": "Q9W1V3-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "MGKPGFSPRGGGGGGGGGGGGFRGRGGGGGGGGGGFGGGRGRGGGGDRGGRGGFGGGRGGGGRGGGGGGGRGAFGGRGGGGGRGGGGRGGGGRGGGGRGGGAGGFKGG-KTVTIEPHRHEGVFIARGKEDALVTRNFVPGSEVYGEKRISVET----NGE---KIEYRVWNPFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVISIKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYRPPPKQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15646-1", "uniprot_id": "FBRL_YEAST", "id": "P15646-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "MSFRP----------GSRGGS-----RGGSRGGFGGRGGSRGGARG--GSRGGFG--GRGGSRGGARGGSRGGFGGR------GGSRGGARGGSRGGRGGAAGGARGG-AKVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * . **. ** * * * :**** * **. * .**. . * *. ** . . : * * :***** **:* ** ** *** *:.** .****:*::* .* * ***.**********.::**::::.: * .***********:******::**:*:*********.**:*:.:****.****::****** *****:**** :*********.**:***:: **:: * .:*****.*****...*:*** **:*:: :.:** ************.:*** * . ", "identical_positions": 175, "similar_positions": 68, "identity": "49.3%" }, { "cls_id": "homologset.agr.HGNC:35459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKA8-1", "uniprot_id": "A0A8I6GKA8_RAT", "id": "A0A8I6GKA8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKPPAVAAAAAAAASEELSQVPDEELLRWS---------KEELARRLRRAEGEK-------------VGLMLEHGGLMRDVNRRLQQHLLEIRGLKDVNQRLQDDNQELRELCCFLDDDRQKGRKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQEALLRENLELKELVLLLDEERAALAAAG---GAGGSGGGAGSRSSIDSQASLSGPLAGSAAGSGARDVGDGSSTSSAGSGGSPDHHHHVPPALLPPGPHKGPEGKAGATRRSLDDLSAPPHHRSIPNGLHDPSSTYIRPLETKVKLLDGD--KLPPQQAG------------SGEFRTLRKGFSPYHSESQLASLPPSYQEVLQNGPACPVPELPSPPSTVYSSAGQKPEAVVHAMKVLEVHENLDR----QLQDSCEEDLSEKEKAIVREMCNVVWRKLGDAASTKPSIRQHLSGNQFKGPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6B2-1", "uniprot_id": "CC85C_MOUSE", "id": "E9Q6B2-1", "name": "Coiled-coil domain-containing protein 85C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKPPAVAAAAAAAASEELSQVPDEELLRWS---------KEELARRLRRAEGEK-------------VGLMLEHGGLMRDVNRRLQQHLLEIRGLKDVNQRLQDDNQELRELCCFLDDDRQKGRKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQEALLRENLELKELVLLLDEERAALAAAG---GAGGGGGGAGSRSSIDSQASLSGPLAGSAAGSGARDVGDGSSTSSAGSGGSPDHHHHVPAALLPPGPHKVPDGKAGATRRSLDDLSAPPHHRSIPNGLHDPSSTYIRPLETKVKLLDGD--KLPPQQAG------------SGEFRTLRKGFSPYHSESQLASLPPSYQEVLQNGPACPVPELPSPPSTVYSSAGQKPEAVVHAMKVLEVHENLDR----QLQDSCEEDLSEKEKAIVREMCNVVWRKLGDAASTKPSIRQHLSGNQFKGPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKD9-1", "uniprot_id": "CC85C_HUMAN", "id": "A6NKD9-1", "name": "Coiled-coil domain-containing protein 85C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKP----AATAAAASEELSQVPDEELLRWS---------KEELARRLRRAEGEK-------------VGLMLEHGGLMRDVNRRLQQHLLEIRGLKDVNQRLQDDNQELRELCCFLDDDRQKGRKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQEALLRENLELKELVLLLDEERAALAATGAASGGGGGGGGAGSRSSIDSQASLSGPLSGGAPGAGARDVGDGSSTSSAGSGGSPDHHHHVPPPLLPPGPHKAPDGKAGATRRSLDDLSAPPHHRSIPNGLHDPSSTYIRQLESKVRLLEGD--KLLAQQAG------------SGEFRTLRKGFSPYHSESQLASLPPSYQDSLQNGPACPAPELPSPPSAGYSPAGQKPEAVVHAMKVLEVHENLDR----QLQDSCEEDLSEKEKAIVREMCNVVWRKLGDAASSKPSIRQHLSGNQFKGPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P485-1", "uniprot_id": "C85CA_DANRE", "id": "Q0P485-1", "name": "Coiled-coil domain-containing protein 85C-A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKN------ITDVSRDDLSKVSDEELQKCS---------KEELLRRLRKVDAEK-------------MNLMLEHGNMMKDVNRRLQLHLHEIRSLKEVNQKLQEDNQELRELCCFLDDDRQKGKKLSREWQRFGRYTASVMWKEVGVFQQKLKELESNQDSVMRENLELKEIIIMLDDER----------------NGAGSRSSIDSQSSLSN-LNGGSA--TVRDVGDGSSTSSTGSAGSPDHHHSH--------IHKPTEGKITSIRRSMDDLSTNHLLRNIPNGLNDSSSNYIRQLETKVRILEDDNKQLLSQQGS------------VGDLKTLRKGLSLYHSESQLSSLS-QFQDTLQNGSIRIAGGDLAPTVTGYLPAAQKPEAVVHAMKVLEVHENLDR----KIPEDYEEDLSEKEKAIVREMCNVVWRKLGDAAGTKPSIRQHLSGNQFKGPL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DHL7-1", "uniprot_id": "C85CB_DANRE", "id": "Q6DHL7-1", "name": "Coiled-coil domain-containing protein 85C-B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAK---------HCPNDDLSKIPDEELVRWS---------KEDLIRRLRRVDGEK-------------MSLMLEHSNMMKDVNRSLQVHLHEIRNLKEINQKLQDDNQELRELCCFLDDDRQKGKKLSREWQRFGKFTASSVWKEVSTYQQKLKELEINQENVLRENAELKDIILMLDEDR----------------NGAGSRSSIDSQSSLSN-LNGGSG--TVRDVGDGSSTSSGGSAGSPDHHHNH--------IHKTVEAKIGTVRRSMDDLSAPHHHRSIPAGLNDASSNYIRQLETKVRILEDNNNKLLSQPCSRYSLSKLSMKYNPGDLRALRKGMTLYHSESQLSSLP-QRQEALLNGTGRLQTSESSPS-TGFISSAQKPEAVVHAMKVLEVHDNLEK----QLPEESEEDLSEKEKAIVREMCNVVWRKLGDATGTKPSLRQQLSGNQFKAPL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQK1-1", "uniprot_id": "Q9VQK1_DROME", "id": "Q9VQK1-1", "name": "", "aln": "MSGNQQQQQQQQKSLTNNAAAAATNEATTLGHNLIKINSVDKIVGKSQAATQAINKLQQQQQQQHQQQQIHQRRSLLPATGGATNPHQPHSSQQQSGTPTPTAQSAAQKQQQQQQQSHQLQTVATIHQPHSTQQQALTSRLPIQQQSTKELPNLAGQQRRSFHYQLQNQQQSLRSPQLKAPAPAHSIPPRYQPPPQPATGILKPHLPLKYPPDIPQLSSIYIPDSIKQQQQQQQQQQSRYLPAHQPGAKDMLKFVRKPDQEHPSPNASVTSSGTGIPTANGGGRLTAEQNRQLQSLVNELRALKEQNQRLLDDNQELRDLCCFLDDDRQKGRKLAREWQRFGRYTASVMRQEVAAYQNKLRQLDDKQQELITDNLELKELCLYLDEER----------------------AHVAANALCAG--CGAATRNALRDDGDGSSSSTN------------------------ADETITALRNYAEQRQLPQDLRHAHT-LNDQTLQYVRSLERRIQQLEEERTTPTAHLQQPTTPTP----QATPTPTVTSAATPAKSAASPHQQQQQQQQHQQQQQDIVAAAAAAAAAIQLPEPIAGRPEAVVRALQVLEVREQLERDRLGNLAGSALDQMDDGEKALVREMCNVVWRKLEGSPHGPAALEPL----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.:.: ::: : * ::: : :*: : *: : . : : ** ** : *:* **: **:* :******:************:**:*******:.:*. : :**. *:**::*: .*: :: :* ***:: : **::* : : ::: :. *.: ** *****:*: : . : *. :: . * *:* : *:* ** ::: *: : .: . . . : * . . *. : :.. . . :*****:*::****:::*:: :: . :::.: ***:************ .:. .::. ", "identical_positions": 102, "similar_positions": 117, "identity": "15.22%" }, { "cls_id": "homologset.agr.HGNC:3546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00451-1", "uniprot_id": "FA8_HUMAN", "id": "P00451-1", "name": "Coagulation factor VIII", "aln": "MQIELSTCFFLCLLRFCFSATR--RYYLGAVELSWDYMQSDLG-ELPVDARFPPRVPKSFPFNTSVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKS-VYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNN-EEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNTGDYYEDSYEDISAYLLSKNNAIEPRSFSQNSRHPSTRQKQFNATTIPENDIEKTDPWFAHRTPMPKIQNVSSSDLLMLLRQS-PTPHGLSLSDLQEAKYETFSDDPSPGAIDSNNSLSEMTHFRPQLHHSGDMVFTPESGLQLRLNEKLGTTAATELKKLDFKVSS--TSNNLIS-TIPSDNLAAGTDNTSSLGPPSMPVHYDSQLDTTLFGKKSSPLTESGGPLSLSEENNDSKLLESGLMNSQESSWGKNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGPSLLIENSPSVWQNILESDTEFKKVTPLIHDRMLMDKNATALRLNHMSNKTTSSKNMEMVQQKKEGPIPPDAQNPDMSFFKMLFLPESARWIQRTHGKNSLNSGQGPSPKQLVSLGPEKSVEGQNFLSEKNKVVVGKGEFTKDVGLKEMVFPSSRNLFLTNLDNLHENNTHNQEKKIQEEIEKKETLIQENVVLPQIHTVTGTKNFMKNLFLLSTRQNVEGSYDGAYAPVLQDFRSLNDSTNRTKKHTAHFSK--KGEEENLEGLGNQTKQIVEKYACTTRISPNTSQQNFVTQRSKRALKQFRLPLEETELEKRIIVDDTSTQWSKNMKHLTPSTLTQIDYNEKEKGAITQSPLSDCLTRSHSIPQANRSPLPIAKVSSFPSIRPIYLTRVLFQDNSSHLPAAS----YRKKDSGVQESSHFLQGAKKNNLSLAILTLEMTGDQREVGSLGTSATNSVTYKKVENTVLPKPDLPKTSGKVELLPKVHIYQKDLFPTETSNGSPGHLDLVEGSLLQGTEGAIKWNEANRPGKVPFLRVATESSAKTPSKLLDPLAWDNHYGTQIPKEEWKSQEKSPEKTAFKKKDTILSLNACESNHAIAAINEGQNKPEIEVTWAKQGRTERLCSQNPPVLKRHQREITRTTLQSDQEE-----------------IDYDDTISVEMKKEDFDIYDEDENQSPRSFQKKTRHYFIAAVERLWDYGMSSSPHVLRNRAQSG----SVPQFKKVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQ--GAEPRK--------NFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKEPFSWIKVDLLAPMIIHGIKTQGAR--QKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGK--VKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06194-1", "uniprot_id": "FA8_MOUSE", "id": "Q06194-1", "name": "Coagulation factor VIII", "aln": "MQIALFACFFLSLFNFCSSAIR--RYYLGAVELSWNYIQSDLLSVLHTDSRFLPRMSTSFPFNTSIMYKKTVFVEYKDQLFNIAKPRPPWMGLLGPTIWTEVHDTVVITLKNMASHPVSLHAVGVSYWKASEGDEYEDQTSQMEKEDDKVFPGESHTYVWQVLKENGPMASDPPCLTYSYMSHVDLVKDLNSGLIGALLVCKEGSLSKERTQMLYQFVLLFAVFDEGKSWHSETNDSYTQSMDSASARDWPKMHTVNGYVNRSLPGLIGCHRKS-VYWHVIGMGTTPEIHSIFLEGHTFFVRNHRQASLEISPITFLTAQTLLIDLGQFLLFCHISSHKHDGMEAYVKVDSCPEESQWQKKNNNEEMEDYDDDLYS-EMDMFTLDYDSSP-FIQIRSVAKKYPKTWIHYISAEEEDWDYAPSVPTSDNGSYKSQYLSNGPHRIGRKYKKVRFIAYTDETFKTRETIQHESGLLGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHARRLPRGIKHVKDLPIHPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINPERDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSIFDENQSWYITENMQRFLPNAAKTQPQDPGFQASNIMHSINGYVFDSLELTVCLHEVAYWHILSVGAQTDFLSIFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDFRKRGMTALLKVSSCDKSTSDYYEEIYEDIPTQLVNENNVIDPRSFFQNTNHPNTRKKKFKDSTIPKNDMEKIEPQFEEIAEMLKVQSVSVSDMLMLLGQSHPTPHGLFLSDGQEAIYEAIHDDHSPNAIDSNEGPSKVTQLRPESHHSEKIVFTPQPGLQLRSNKSLETTIEVKWKKLGLQVSS--LPSNLMTTTILSDNLKATFEKTDSSGFPDMPVHSSSKLSTTAFGKKAYSLVGSHVPLNVSEENSDSNILDSTLMYSQESLPRDNILSMENDRLLREKRFHGIALLTKDNTLFKDNVSLMKTNKTYNHSTTNEKLHTESPTSIENSTTDLQDAILKVNSEIQEVTALIHDGTLLGKNSTYLRLNHMLNRTTSTKNKDIFHRKDEDPIPQDEENTIMPFSKMLFLSESSNWFKKTNGNNSLNSEQEHSPKQLVYLMFKKYVKNQSFLSEKNKVTVEQDGFTKNIGLKDMAFPHNMSIFLTTLSNVHENGRHNQEKNIQEEIEK-EALIEEKVVLPQVHEATGSKNFLKDILILGTRQNIS--LYEVHVPVLQNITSINNSTNTVQIHMEHFFKRRKDKETNSEGLVNKTREMVKNYP---------SQKNITTQRSKRALGQFRL----------------STQWLKTINCSTQCIIKQIDHSKEMKKFITKSSLSDS-SVIKSTTQTNSSDSHIVKTSAFP---PIDLKRSPFQNKFSHVQASSYIYDFKTKSSRIQESNNFLKETKINNPSLAILPWNMFIDQGKFTSPGKSNTNSVTYKKRENIIFLKPTLPEESGKIELLPQVSIQEEEILPTETSHGSPGHLNLMKEVFLQKIQGPTKWNKAKRHGES--IKGKTESSKNTRSKLLNHHAWDYHYAAQIPKDMWKSKEKSPEIISIKQEDTILSLRPHGNSHSIGAN-EKQNWPQRETTWVKQGQTQRTCSQIPPVLKRHQRELS--AFQSEQEA-----------------TDYDDAITIET-IEDFDIYSEDIKQGPRSFQQKTRHYFIAAVERLWDYGMSTS-HVLRNRYQSD----NVPQFKKVVFQEFTDGSFSQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYKEDQR---GEEPRR--------NFVKPNETKIYFWKVQHHMAPTEDEFDCKAWAYFSDVDLERDMHSGLIGPLLICHANTLNPAHGRQVSVQEFALLFTIFDETKSWYFTENVKRNCKTPCNFQMEDPTLKENYRFHAINGYVMDTLPGLVMAQDQRIRWYLLSMGNNENIQSIHFSGHVFTVRKKEEYKMAVYNLYPGVFETLEMIPSRAGIWRVECLIGEHLQAGMSTLFLVYSKQCQIPLGMASGSIRDFQITASGHYGQWAPNLARLHYSGSINAWSTKEPFSWIKVDLLAPMIVHGIKTQGAR--QKFSSLYISQFIIMYSLDGKKWLSYQGNSTGTLMVFFGNVDSSGIKHNSFNPPIIARYIRLHPTHSSIRSTLRMELMGCDLNSCSIPLGMESKVISDTQITASSYFTNMFATWSPSQARLHLQGRTNAWRPQVNDPKQWLQVDLQKTMKVTGIITQGVKSLFTSMFVKEFLISSSQDGHHWTQILYNGK--VKVFQGNQDSSTPMMNSLDPPLLTRYLRIHPQIWEHQIALRLEILGCEAQQQY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZEB1-1", "uniprot_id": "D3ZEB1_RAT", "id": "D3ZEB1-1", "name": "", "aln": "MRAARGLCFFLSLCALCSCATR--KYYLGAVELPWDYVSGGASGAQRSDSRFPPGTPAPS---AHVVHTKTVFVEYMDRFFHTAKPRPLWMGLLGPTIWTEVHDTVVITLKNMASHPVSLHAVGMSFWKASEGAAYDDHSSPAEKDDDKVLPGESHTYAWQVLGESGPMASDPPCLTYAYLSHVDLVRDLNSGLVGALLVCKEGRLSADRTRMPPHFVLLFAVFDEGRSWHAATR-------DPASTEAQPTVHTVNGYTNRTLPGLTGCRGTS-VYWHVMAVGTTPDIHSILLEGHTFSVRSHRQASLEISPMTLLTAQTWLMDLGRFLLFCHISSHRHGGMEAYVQVDNCPEAPQGQGKRD-EDTEDYDD--LDSEMDVFTWDPDAAP-FVQVRSAAKRHPKTWVHYIAAEEGDWDYAPAAATLEDGSLRNRYLGRGPGRIGSKYKKVRFVAYTDGTFHTREATPREAGLLGPLLYGEVGDSLLIVFKNRASRAYNIHPHGIRDVGAVHAGRLPRGVKHVKDLPIRPGETFKYRWTLTAEDGPARSDARCVTRYYASAVDPERDLASGLIGPLLICCKESVDQRGNQMMSDERNVILFSVFDENRSWYISENMRRFLPDEAHVQLQDPEFEASNLMHSINGYVFDSLELRVCLHEVAAWHVLSVGAQTDFLSVFFSGHTFRHRAVYADTLTVFPHSGVTVFMSMDNPGVWVLGCHNPDFRESGMTALLKVSSCDEGVSDYYGETYEGVLAPLAN-DNAVDPRSFSQNSNHLHSRKK--------------------------------KSNTPMRFPLSHPTQHGSFWSDSQGDVHDAVHRAHSPAAAHSNEGPAEAAQLEPKPHPGEKMALPPS---WLRAKRSLVTTMEAKRKKLDLQVQVSGLPDDRTTAVVAPDDPMAACKKAGSSGFP-------DESSPAALGKKMYPRIRPHGPLSIIEGNRDSNSSDSTLMYRLGSPPGDATSWTENRRGLGEKRSHRVAFLARGNTLLSD---------------VDEKSHAPGPTSVGNSTAAVQDTILEICSEILEVTPPIHDRILSDKSATYLRPHRTPDRITSTERKDIRHKKDGDLVPQDADDTSAPFSEAPFLSESTDWLKEANGDNSAKPEQEPSPEQLVYLMYIKCMENQSFSSEKNKMIAGQGGFTKNTGLEDTVFPRKTSVFLTTVAKRQESGRHNQE-NIPQAVTEKEAPIEEKGALPQVHIATGSKNFPRDMFVLGTGQNIN-LHEETYVPVHKNVPWTRNPTDTRQIPMVHFFKKRKEEETNSGGLVNKTRETVRNYP---------SQKNSVARRREQASGRIKA----------------SARWLPDVNRSIQSLLKQIDHRKERKKFIIESRSADS-SGTKSPTQTNHSPSHVVKMSAFP---PRDIRRIESRD-SSQVWVSSYAYDFETGSSRIRESSPFLNETETDNPSLAVPPRERFVRRGRFASPEKVNTHSAPCDKPENVVSSEPVSPGEAVTVALPPHVSTQEEEPLPAGSSCERRGHVDLFLEISLQRTRGPVERSRGRRSGGD--TEGHTENPGKTPSPLP-----------QMPKDQRGSEAGYPKICRWR-DGTVLPPRPHN--LSLGAK-KKPNLPRREATRVEQGEAPSLVSPEPLVLRRRPREASTLLPGGEMREDDGDGVTAEYDDDDDVMAEYDDDAVTVDTPEDFDIYGEEAGQGPRGFQQKTRHYFIAAVEELWDYGVRVSPGALGDRAWSG----DAARFRKVVFREFTDGSFTQRVHRGELDAHLGLLGPYIRAEVEDNIVVTFRNQASRPYSFYSSLVSYPEADG---GAAPRS--------NFVRPNETKTYFWRVRPHMAPTDGEFDCKAWAYFSDVDLERDLHSGLIGPLLVCHASTLHPSHARPLAVQEFALLFAVFDETKSWYCAENLDRKCRPPRGTPAGDPAWREEYRFHAVNGYVADALLGLVMAEGRRTRWHLLSMGDPGHAQSVHFSAHSVTVRDGGEHRTAVCNLYPGVFTTVEMLPSRAGIWRVESLVGEHLQAGMSALFLVYSTRCQVPLGMASGYIRDSQITASGYHGLWTPQLARLHNAGSVNAWSAKEPFAWIKVDLLAPMILHGIETQGAR--HRLSSLYVSQFIIMYSLDGKQWLSYRGNSTGSLMVFFGNVDASTVRHNRFDPPIVARYIRVHPTHASIRTALRMELLGCDLNSCSAPLGMESGWISDTQVTASSHLSTTFSAWPPALARLHLRGGANAWRPQVNDPTQWLQVDLQRTVKVTGVVTQGARSLLTAMFVKKFLVSTSQDGRHWTHVLQDGK--VKVFQGNRDASTPMVNSLHPPRFTRYLRIHPQVWERQIALRLEILGCEAQQLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3BEX0-1", "uniprot_id": "A0A8M3BEX0_DANRE", "id": "A0A8M3BEX0-1", "name": "", "aln": "MKTLLFLLLLSACQEYSCVSAKTLEFFIAAVETKWEYVFTDTADPAANQRKFAS---------GVQKYTKAVYTEYTDSTFTTPKSKPPWAGIQGPTIRTVVNDRVVVHFKNFASQSFSISPIGIPYWKQSEGAGYEDSSSFQERADDSVPPGGYYRYVWDISPNSGPTTSDPDCLTYIYSSQVDIIRDFNSGLIGALLICKTDALTEDRQRRVPEFILLLSVFDESKSWYQEVG----RAEKLKKTSSTNQYHTINGYINSTLPGLSVCEKSPQVSWHLIGLGSSPEIHSIQFEGHTLKVFDHKRVTVEMTPMTFTTALMKPSATGRFLISCRIHSHQTAGMNAFFTVENCPEPAPLPLPDKRNVKHTNDDEEEDDEDNMFSVVFKQGGPISVLRSSAKGRPKVWLHYISAEETDWDYTAQSGDRPASSAGSEWFRKGPQRLGGVYKKVAFVEYTDKTFSVKKTTGRT--LIGPELRGEVGDKFQIVFKNMASRPFNIYPNGLTSVQPLKTTNKDK-QVDLRSLAVPPGEIMTYLWKLTAEDGPTDADPRCLTRIYQSTLDPARDVASGLVGPLIICKSQSLDKRGRVVTSDKEKKLLFTVFDENRSWYFEENIKRNSEDPAKINRNDLDFYNSNIMHTVNGFMFNHLQYKMCVGDVILWHVASIGMQNNFLSVYFTGNTFEREKAYGTVLTLFPMTGDTVTTEVEMMGEWEVSAFDPSLKERGMSVRYTVVNCERVLPKVDYDDYDEEFMEIIEKNFPNPRGTMGKN-------------------------------------------------------------------------------------------------------------------------------RTIAIRVCR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------NRTVTD-SGSNTRHNETLNRSRVCEIR---------YVPVKEENDLEALSQGGIPQDILDQLDDEIGGNSVERQK------------RSHQESHTVTSSYTELPQNQHNETQAG-------------------------------------------------------ADTTNELLRKFLFKHTNLNIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRTQDEMEESLNPLSFNTIRN--ISMVEIEKARSRRELWSVGKTNQKDVKAMS-DNEVLEDSGRKRDKMEESLNPLSYNYKDLKKYSEMG---------------------LEPASNSSDDK-----------------------------------MYGKKSVTSDYDDYSDEGSVVG---------------------------------------------------------------------------------------------LDHFVEDN-VGVRSTESKFRSYYIAAEEVMWDYGIDKPAQLIKPREMRRGLRKYFPTYKKVVFRAYQDRDFRHPIKRGELDEHLGIMGPVVKAEINDVLTVVFKNLASRPYSFHLHGVYDKTPGSFSTGMGPENPKLEEEAGDPVPPGEERVYNWRISRRQGPSASEFDCKAGAYYSNVNMEKDINSGLIGPMLICRPGTLNPRVLLQPDVTDFFLLFTTFDERKSWYLDYNIRKFCIPPCQARVDDPWFQTSNKFAAINGYVSETLPGLRVEQYRTARWHLLNLGTQGEFHAVHFHGLPFRVGKDQEHRMGIFNLYPGVFGTVEMRPAIAGTWLIECTIGEHQLAGMRAKLLVYNPQCNQPIGMQSRWITNKQITASDYYGDWKPELARLELTGSINAWMGSSPNSWLQVDLLRPMILHGIQTQGAKTSMGLSEFFTILYSISYSNDQENWSVYRGNSTKPYYTFNGNMDGSRIKENLFSPPIVGRYIRIHPLTFQKQPTLRIELLGCDLNSCSLPLGMERRSIPNSSISASSFLNKWLLSWSPDLARLHQEGRANAWRPKSNNPHEWLQVDFASVKRVTGLITQGARSVLKPMMVTEFTVSVSNDGHSWSSVTEQGTDSEQIFEGNSDNNEETLNIFDPPLFTRFIRVHPKGWVNDIALRLEFLGCDTQPTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: . . : : .:::.*** *:*: . : :* . :.*:::.*: * * .*.:* * *: **** : * * **: :**:**:..*: .:*:.:** *** *:* :* *: **.* ** : *.*:: :.** :*** **** * *:**:::*:****:****:*: . *: :: : .*:**::****.:**: . . .: **:*** * :**** *. .. * **::.:*::*::*** :****: * .*::.::*::*:*: ** *:**: *:* **: **:*:. *:.*** . . : . ** . * ::. . . : :** ** **.*:***:*** ****:. * ..:: .** *:* **** *: *** ** .::: : ::** * *****.: *:*** ***.:**:*:*: .* .: : . : .::.:.: *** :.* *.:*.****: :*.**:** * * :: **:****:***:** .:*:*:**. : **:.: :**::****:***: **::* : * : :* * **:**::**::*: *: :*: :* *:: *:* *.:***::*:* **.:. .* .**:** :* ** .:: * * :...:..::: **:. .* .*:. . : *: : . : :: :* :.: ::* : : . ..: * :. :: : :* . :: .: : : : :. * ** : : . :.:.. *. .:: : *: . :::: :.::. * *:. . .. :.** *. * ::: : : .. * . :.. . :* : .. * * :. : . : . .: .. ..::: :* : *: . *. :.* * *:*** * :****: . : * . ::****: : * .* : : ****: ***::** ::**::* : *.*:* *******: : * *. : * *.* : * *:: : .*: .****** **:*:*::*:*::******:*:*:..**:* * :* *:*: *** **** *: : * .* ** : . :* *:***: ::* ** : : : **:**.:* . :::** . . * . *:: .: ******* *:** *: ** * :*. :*** *** : :***. :*: *:** * * : *****. :* * *:****. :**:*** ..* :*::**** ***:***:****: :*.:: : * ** * ::* *:**** . .* **:*.* ::.* *.***:.****:** . :.:**:**:******** ***** *.::.::***.:.. : :*.* **** .* :*****: *:* :*****: . :***: ***.:*::..* *.:* :* *:**: *: . :*. ::*:** * :* :.** :**::*:**: * .:****:*.***::* ", "identical_positions": 556, "similar_positions": 529, "identity": "23.16%" } ]