[ { "cls_id": "homologset.agr.MGI:1928842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQ60-1", "uniprot_id": "CAC1H_RAT", "id": "Q9EQ60-1", "name": "Voltage-dependent T-type calcium channel subunit alpha-1H", "aln": "---------------------------------------------------------------------------------------MTEG------------TLAADEVRVPLGASPPAPAAPVRASP-------------------------------------------------------------------------------------ASPGAPGREEQGGSG-SGVLAPESPGTECGADLGADE----------------EQPVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVMAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLD------------SAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQKCSHIPSRRELRVQCTLGWEAYGQPQAEDGGAGRNACINWNQYYNVCRSGEFNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIMGSFFMINLCLVVIATQFSETKQRENQLMREQRARYLSNDSTLAS---FSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKK--------------VDPSSTVHGQGPGRRPRR-------------------------------------AGRRTAS-----------------------------------------VHHLVYHHHHHHHHHYHFSHGGPRRPS----------------------------PEPGAGDNRLVRACAPP--------------------------SPPSPGHGPPDSES-------VHSIYHADCHVEGPQE-----RARVAHSIATAAS-LKLASGLGTMNYPTILPSGTVNSKGGTS-----SRPKGLRGAGAPGAAVHSPLSLGSPR-PYEKIQDVVGEQGLGRASSHLSGLSVPCPLPSPQ---AGTLTCELKSCPYCASALED---------------PEFE----FSGSESGDS---------------------DAHGVYEFTQDVRHGDCRDPVQQPHEVGTPG--HSNERRR-----------------------------------TPLRKAS-QPGGIGHLWASFSGKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVVISVWEIVGQANG--------GLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSG----------------DTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEG-----------------------------DATRSDTD--------------------------------EDKTSTQLEGDFDKLRDLRATEMKMYSLAVTPNG--------------------------------------------HLEGRGSLP-----------------------PPLITHTAATPMPTPKS--------------------SPNLDVAHALLD--------------------------------------------SRRSSSGSVDPQLGDQKSLASLRSSPCTPWGP---------------------------------------NSAGSSRRSSWNSLGRAP-----SLKRRNQCGERES-----------------LLSGEGKGSTDDEAEDSRPSTGTH------------PGASPGPRATP-----------------------LRRAESLDHRSTLDLCPPRPAALLP-----------------------------------------TKFHDCNG----------------------------------------------QMVALPSEFFLRIDSHKEDAAEFDDDIEDS----------------CCFRLHKVLEPYAPQWCRS-RESWALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECH-AAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRR------KAQRRPYYADYSHTRRSIHSLCTSHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMN--AALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLS---YLPALSPVYFVTFMLVAQFVLVNVVVAVLMKHLEESNKEAREDAEMDAEIELEMAQG------STAQPPPTAQESQGTQPDTPNLLVVRKVSVSRMLSLPNDSYMFRPVAPAAAPHSHPLQEVEMETY-----TGPVTSAHSPPLEPRASFQVPSAASS-PARVSDPLCALSPRGTPRSLSLSRILCRQEAMHSESLEGKVDDVGGDSIPDYTEPAENMSTSQASTG--APRSPPCSPRPASVRTRKHTFGQRCISSRPPTLGGDEAEAADPADEEVSHITSSAHPWP-ATEPHSPEASPTASPVKGTMGSGRDPRRFCSVDAQSFLDKPGRPDAQRWSSVELDNGESHLESGEVRGRASELEPALGSRRKKKMSPPCISIEP-------PTKDEGSSRPPAAEGGNTTLRRRTPSCEAALHRDCPEPTEGPGTGGDPVAKGERWGQASCRAEHLTVPNFAFEPLDMGGPGGDCFLDSDQSVTPEPRVSSLGAIVPLIL-ETELSMPSGDCPEKEQGLYLTVPQTPLKKPGSTPATPAPDDSGDEPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88427-1", "uniprot_id": "CAC1H_MOUSE", "id": "O88427-1", "name": "Voltage-dependent T-type calcium channel subunit alpha-1H", "aln": "---------------------------------------------------------------------------------------MTEG------------TLAADEVRVPLGASPSAPAAPVRASP-------------------------------------------------------------------------------------ASPGVPGREEQRGSG-SSVLAPESPGTECGADLGADE----------------EQPVPYPALAATVFFCLGQTTRPRSWCLRLVSRRWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVMAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLD------------SAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQKCSHIPSRRELRVQCTLGWEAYGQPQAEDGGAGRNACINWNQYYNVCRSGEFNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQRARYLSNDSTLAS---FSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKK--------------VDPSSTLHGQGPRRRPRR-------------------------------------AGRRTAS-----------------------------------------VHHLVYHHHHHHHHHYHFSHGGPRRPS----------------------------PEPGAGDTRLVRACVPP--------------------------SPPSPGHGPPDSES-------VHSIYHADCHVEGPQE-----RARVAHTIATAAS-LKLASGLGTMNYPTILPSGAVNSKGSTS-----SRPKGLRSAGTPGATAHSPLSLGSPS-PYEKIQHVVGEQGLGRASSHLSGLSVPCPLPSPQ---AGTLTCELKSCPYCASALED---------------PEFE----FSGSESGDS---------------------DAHGVYEFTQDVRHGDCRDPVQQPHEGGTPG--HGNERWR-----------------------------------PPLRTAS-QPGGLGRLWASFSSKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIVGQADG--------GLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSG----------------DTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEG-----------------------------DATRSDTD--------------------------------EDKTSTHLEEDFDKLRDVQATEMKMYSLAVTPNG--------------------------------------------HLEGRGSLP-----------------------PPLITHTAATPMPTPKS--------------------SPHLDMAHTLLD--------------------------------------------SRRSSSGSVDPQLGDQKSLASLRSSPCAPWGP---------------------------------------NSAGSSRRSSWNSLGRAP-----SLKRRSQCGERES-----------------LLSGEGKGSTDDEAEDSRPNSGTH------------PGASPGPRATP-----------------------LRRAESLGHRSTMDLCPPRPATLLP-----------------------------------------TKFRDCNG----------------------------------------------QMVALPSEFFLRIDSHKEDAAEFDDDIEDS----------------CCFRLHKVLEPYAPQWCSS-RESWALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECH-AAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSTFPNPEAQRRPYYADYSHTRRSIHSLCTSHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMN--AALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLS---YLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAEMDAEIELEIAQG------STAQPPSTAQESQGTEPDTPNLLVVRKVSVSRMLSLPNDSYMFRPVAPAAAPHSHPLQEVEMETY-----TGPVTSAHSPSLEPRTSFQVPSAASS-PARVSDPLCALSPRDTPRSLSLSRILCRQEAMHAESLEGQIDDAGEDSIPDYTEPAENISMSQAPLG--TLRSPPCSPRPASVRTRKHTFGQHCISSRPPTLGGDDAEAADPADEEVSHITSSAHPWP-ATEPHSPEASPTASPAKGTVGSGRDPHRFCSVDAQSFLDKPGRPDAQRWSSVELDNGDGHLESGEVRARASELEPALGARRKKKMSPPCISIDP-------PTEDEGSSRPPAAEGGNTTLRRRTPSCEAALHRDCPESTEGPGTGGDPVAKGERWGQASCRAEHLTVPNFAFEPLDMGGPGGDCFLDSDQSVTPEPRVSSLGAIVPLIL-ETELSMPSGDPPEKEQGLYLTVPQTPLKKPGSPPATPAPDDSGDEPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95180-1", "uniprot_id": "CAC1H_HUMAN", "id": "O95180-1", "name": "Voltage-dependent T-type calcium channel subunit alpha-1H", "aln": "---------------------------------------------------------------------------------------MTEG------------ARAADEVRVPLGAPPPGPAALVGASP-------------------------------------------------------------------------------------ESPGAPGREAERGSE-LGVSPSESPAAERGAELGADE----------------EQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLD------------SAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLAS---FSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKK--------------VDP-SAVQGQGPGHRQRR-------------------------------------AGRHTAS-----------------------------------------VHHLVYHHHHHHHHHYHFSHGSPRRPG----------------------------PEPGACDTRLVRAGAPP--------------------------SPPSPGRGPPDAES-------VHSIYHADCHIEGPQE-----RARVAHAAATAAASLRLATGLGTMNYPTILPSGVGSGKGSTS-----PGPKGKWAGGPPGTGGHGPLSLNSPD-PYEKIPHVVGEHGLGQAPGHLSGLSVPCPLPSPP---AGTLTCELKSCPYCTRALED---------------PEGE----LSGSESGDS---------------------DGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRR-----------------------------------AQQRAAPGEPGWMGRLWVTFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADG--------GLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTG----------------DTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEG-----------------------------DANRSDTD--------------------------------EDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNG--------------------------------------------HLEGRGSLS-----------------------PPLIMCTAATPMPTPKS--------------------SPFLDAAPSLPD--------------------------------------------SRRGSSSSGDPPLGDQKPPASLRSSPCAPWGP---------------------------------------SGAWSSRRSSWSSLGRAP-----SLKRRGQCGERES-----------------LLSGEGKGSTDDEAEDGR--------------------AAPGPRATP-----------------------LRRAESLDPR------PLRPAALPP-----------------------------------------TKCRDRDG----------------------------------------------QVVALPSDFFLRIDSHREDAAELDDDSEDS----------------CCLRLHKVLEPYKPQWCRS-REAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCR-AAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMS--AALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLS---YLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGAR-DAPN-LVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQIPLAVSS-PARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRD--TLDPAEPGEKTPVRPVTQGG-SLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVA-------GGERDLRRLYSVDAQGFLDKPGRADEQWRPSAELGSG----EPGEAKAWGPEAEPALGARRKKKMSPPCISVEP-------PAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPSATPAPGGGADDPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PGH9-1", "uniprot_id": "M9PGH9_DROME", "id": "M9PGH9-1", "name": "", "aln": "MLPQPAAAVATATTTTTQSATSATSTAATSAAAAAARNGQRRRVAAATEGCNSNIGNSNSKLSSNTTTNTTKRVSQMHSNEEPPMTVIVDGGGGSNVSVSGGSSHRRGSQRLRKTSSSSANAKSASANPTERTSSGQRSSHRQTSNASDGGGSSRRRYQGKEHHDRRDRQDRQDRQDRQERSDRHERRDRRDEQQAARRRTGRRHSGASSLSDAAAATAAGRSRSRGGGRTGGAVSSSTGSSCNGSCSSDDGDSSHTSSSSSSSSSGEPNLPYPGFPEISIRALTQYTRPRNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYPLTVPEVYRVRVRVNSLSQYYEFSKDQD--YICSTPNDSGMHLCGNFPPYRIGSLVCNEEAKLFDFNEPTN-----TSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKREMERMRQERARYTS-TSTLASSTNNSEPATCYAEIVKYIAHLWRRFKRRMLKKYRLYKYQRQQRKEGLLPNADNLTFSPSRIKCHHPKCPKYSNRKPSSIQDQMITVMVPLNSASNNINNNNNNNSNSSNHNGSGNHTAAGGGNNNNNNNNNNAASCTTVALVNGINGSAASVTMSSAHHQQHQLLQHQQQQHQNQQQQQQQQQHSSSDNTEQSLAPDGLPRSSSLKKSTAHHQLKPEGSAAEQKTILLKFPQQMIDSEQLILQLGNLGKSHPCTSGFLSPPTSASRRPSVMFNEYVLLHTPPALNADPATAGTTTTVAPTVATVAGTAAAAAAAAATGSGSGNNNHQNGGASGGAGTGGTTEKSNIFSTEKMTQAGDGSIWQVNLPQTIGTIANPYADCSELGIHDAMTCQELLAFSVAFSAALPTGQSTLESFYTSLARCDPHTAEALRAHHKPRSVPTGQNQTTPGAEGATVMVASTAGDTGQTLQPSTVSAVVGGTIDSHAANHRRKEHHQQSHHHHNNNNTTSHSRNYRSRQGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKKLREETLAENYSDGMYDESRSEADSSTTNDSYYEVRNRWRSAEDVRKLQDSVELIIEAKSNMHRQRLLQPTHDYQINELPASSAAPSASGTSGASAPGDRERDRDRDRDRERDRDRDRERDREAGGGGKEEGAQHAKPRGGLKKTYSIKERRSEAPRLSKIRLARDPPIITTTAATPQDSPSTTLEPGMSFRQWGDMEPPSPPSPSLLRPPNIFTGGQRSLDEGIPSIDLIPPSPVLSHKPLNILNASQLGVGMGGGVPSTAGSSSSMHSVIIDDISKSSSSTAAATPIYVPTISSTADAQSQSHSLNDVSVGSSPGGEIPATGMSRNANTGASTSGSSSSERLPLAPPPQQGSFKQRLRRGSSKKRRASALALATDDNPARRTLDNQARRTQDEEEEQQQLNNGGDNSCLLRNSNAVVSGSSSGTKETNRLSPQNSIRRLSNTLSIGSGPVGSRRASACIFNSQVYQNLNQPPKLRPGSGQRRMSSIELAFSKTSHLNLHNLEANRKSLSYTNSKMDLDKWNKSYGNLNEPDNMLQQYMEARDKRKNSISHYNLKKRLEEKELQQLQQLHQQQLLQQRQDSFSSTTQQQQQQLQQHRLSKDQQQLAMQPHSMVPGGGERYSKLKMLIEQLTPKHFTTEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKKRR------RMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDELDMEVELERELVRE---------QEFAQEQKLCQQLAEAQSKAAAPPRPLAKVKSLPKNFIYSTPSLDKKFPAVSGVNNPSLTSS----AATNLNQVATAGSGGAAPGAVPAGSGAGPRRQTVQYFQQPPQSMLGGLSLAEMGG---TLTPQALGARLGEPFGGGGGNKSGPRRQSYWQINPIRKRGVLSKERSLDEQAIRRRNLEAKRTSCDSLP--WGGDALDCRRGTIFESLESDGGGVGGGGSGGGGGGLG----------GGVSYDLRSVRSADVG--HSEMDGDVSLSVVSALVPSVTTPLPPPLSLPIVTPTSTPTPLQLPMPMPMPMAHPPPRRPFGWSQSVDQGCLRSNLLLSVPRSMPPRSRSGSTKQLFKQQALDEDADMDENSLLLPTAAGGGSGPGSVAVIASSSLDLPDQSGSSKQILPDIALGVSK----SDSSDILRIISERRRMDQREQREPEQDQDNEAEDRDSDYK---ELLLVKSPQSSMD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* : .. *: :.... * . *.* :. ..**. . *. . ..*..:. ... .:*: * :***.:. : .* * ****.*** *: . ***::*:***:***:****::** * * ::**.**: ** :******:**.*****:*: *:: **.*:*********:**::** :. .*:.*:****:***********:******* *************************:***** *:**:** * ..: . .:. * **: .:.:: :***: .*.**: *.::* * : *. : : :. . .:*:******..*:.. **.:*:*.***** **:*** **:****.****** *****:::***:***::*********************:** : **::***: * ***** ***.:** *::**:.*::*:.*** *: * :: : ::: . . : : * *: :*.:**: *:*: *::::*::: : .: : .. ** .* : : : * ***:.. *. . . :** *. * ** : *:**: .:* *. *: . .** . * *. . * ... . : * ::.: ** . .: ...: .::....**: . *. :. *: : **. * * : .* :**: : *. *: :* . : . . .. : * . * :.:: : :**:*: ***.:**: ***:******:***:** *** :* **:**:.:**:*****::* **: ** * :*:****:*::*. ** * ************:******:* *****.*:::******.* **:***********:*** **. * . : ***:*:.:*** ****************:*** .** *****************************.:* * .**::* * *:. : : :. :: : .*: * * :..* * : **.* **:* ***** :*.: ** * . : * .**.* .. : *: . :* ::..:* ..* :* ** . * ** *:*:* : *. :. *..:.: : *:* *: : ::.*.: * ***.: . :*. * * * .. * *:: .: * .:::: : . :*. :*: ::* *: : ** ::**:*. :**:* * .: :* **:***:** ***:*:*:***:* *.**** **:.:**:**.:*..**::**** *:: *..**: *.**::** ** :*::*::::: * ...:*:*:***:****:*******.*********:**:**************:***************.****** : :.: . :*: . *..******:**:**********:******** ******:****: *:* * *****:*:*:*.****************:**:.** ** ** ** ::*::** . :. ***::** ** :*.: **:*:** *: :* :**:**:**:*: *..*. *** **.** **::** :****:*:: ::********:.*****::**.***:* . :********:****************.*:*******:*************:*****:**************:: **:**..** *:************:**************: : .*: ..::*::** *:*:********************:*: .:: :::.*:* *:.: : . *: :: . .. .:::: ***:: * * ::: .: : : .. :. :. :* . .: * * .*:. . **:.: :: .::* .::.. : : * .: . * * ::* *: : . .* * **: :. : * . ... : . . * * : . *.*. .: . *. : . . . ... : *. * * : *:*. *. . :: *: * .: . *... . :. * .* .. .:.. ::: * . .. : : * .*: *. . *: : . . **: :. : : . . :* .. * ", "identical_positions": 957, "similar_positions": 675, "identity": "29.25%" }, { "cls_id": "homologset.agr.MGI:1928849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C6B8-1", "uniprot_id": "SVEP1_RAT", "id": "P0C6B8-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "MWTRLAFCCWALALVSGWTNFQPMAPSLNFSFRLFPEASPGALGRLAVPPRSGEEEAVGSKVERLGRTFRSRVRRLRELSDRLELVFLVDESSSVGQTNFLNELKFVRKLLSDFPVVSTATRVAIVTFSSKNNVVARVDYISTSRAHQHKCALLSREIPAITYRGGGTYTMGAFQQAAQILRHSRENSTKVIFLITDGYSNGGDPRPIAASLRDFGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQEDMAHCSYLCEAGRDCCDRMASCKCGTHTGQFECICEKGYYGKGLQYECTACPPGTYKPEASPGGISTCIPCPDENHTSPPGSTAPEDCVCREGYQRSGQTCEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTVEMSYNTVCLVTCNEGYRLEGHAKLTCQGNAQWDGTEPRCVERHCATFQKPKGVIISPPSCGKQPAKPGMICQLGCRQGYILSGIREVR-CATSGKWSARVQTAVCKDVEAPQISCPNDIKAKTEGQQDSANVTWQVPTAKDNSGEKVSVHVHPAFSPPYLFPIGEVAITYTATDSSGNQASCTFYIKVIDVEPPVIDWCRSPPPIQVVEKEHPASWDEPQFSDNSGAELVITSSHTQGDLFPHGETVVWYTATDPSGNNRTCDIHIVIKGSPCEVPFTPVNGDFICAQDSAGVNCSLTCREGYDFTEGSTEKYYCAFEDGIWRPPYSTEWPDCAIKRFANHGFKSFEMLYKTTRCDDMDLFKKFSAAFETTLGKMVPSFCSDADDIDCRLED-LTKKYCIEYNYNYENGFAIGPGGWGAGNRLDYSYDHFLDVVQETPADVGKTRSSRIKRTVPLSDPQIQLIFNITASVPLPEERNDTVELENQQRLIRTLETITNRLKSTLNKGPMYSFQLASETVVADSNSLETEKAFLFCRPGSVLRGRMCVNCPLGTSYSLEHSTCESCLMGSYQDEEGQLECKLCPPRTHTEYLHSRSISECKAQCKQGTYSSSGLETCESCPLGTYQPDFGSRSCLPCPETTTTVKRGAVDISACGVPCPVGEFSRSGLTPCYPCPRDYYQPNAGKSFCLACPFYGTTTITGATSITDCSSFSSTFSAAEESIVPLAAPGPTQNKYEV----FHECFLNPCHNSGTCQQLGRGYVCLCPPGYTGLKCETDIDECSSLPCLNGGICRDKVGGFTCECSSGYTGQICEENINECSSSPCLNKGTCTDGLASYRCTCVSGYVGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGTRCEKNVDECLSQPCQNGATCKDGANSFRCQCPAGFTGPHCELNINECQSNPCRNQATCVDELNSYSCKCRPGFSGRRCETEQPSGFNLDFEVSGIYGYVLLDGVLPTLHAITCAFWMKSSDVINYGTPISYALEGNKDNTFLLTDYNGWVLYVNGKEKITNCPSVNDGIWHHIAITWTSTGGAWRVYIDGELSDSGTGLSVGKAIPGGGALVLGQEQDKKGEGFNPAESFVGSISQLNLWDYVLSPQQVKSLASSCPEELSRGNVLAWPDFVSGITGKVKVDSSSIFCSDCPSLEGSVPHLRPASGDRKPGSKVSLFCDPGFQMVGNPVQYCLNQGQWSQPLPHCERIRCGLPPTLENGFYSAEDLHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYICSCKPPYTGDGKNCAEPVKCKAPENPENGHSLGKIYSVGAEVTFSCEEGHQLVGVRKITCLESGEWDHLRPSCEAISCGAPPVPENGGVDGSAFTYGSKVRYRCDKGYTLAGDEESACLASGSWSHSSPVCELVKCSQPENINNGKYILSGLTYLSIASYSCEDGYSLQGPSLIECTASGSWDRAPPSCQLVSCGEPPMVKDALTTGSNFTFGNMVTYTCKEGYTLAGPDTIICQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPEGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGQWSPSPLSVQCIPVRCGEPPSITNGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSRPLPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAVGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLRGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELTSEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPVCKLVLCQSPPLIPFG-VPASSGALHFGSTVKYLCVDGFFLRGNPIILCQVDGTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNTTTLCGENGQWLGGKPMCRPIECPEPKEILNGQFSSVS--FQYGQTITYSCDRGFRLEGPKSLTCLETGNWDMDAPSCNAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVVGHAMQTCEETG-WSSSSPTCVPIDCGLPPHIDFGDCTRVSDGQGYFVQEDDMMEVPYLTP-HPQHLEATAKASEITEESLVPHASQFLYGTTVSYRCEPGYELLGIPVLVCQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHVLEGSHLRLCLQNKQWSGTVPRCEVISCSEPNPLGNGSIKGNDYSYLGVLHYECDSGYVLNGTEKRTCQENKQWDGHEPVCLPVDCGSPPVPTNGQVTGEE--YTFQKEIAYSCGEGFILEGARSRVCLTNGSWSGTTPSCVPVRCPAPPQVANGVTDGLDYGFKKEVTFHCLEGYVLQGTPKLTCQSNGTWDAEVPICKPATCGPPADLPQG--FPNGFSFFHGGHIQYQCFTGYKLHGNPSRRCLPDGSWSGSTPSCLPCTCSTPIIQQGTVNATDLGCGKTVQIECFKGFKLLGLPEITCDANGQWSD-FPLCEHADCGPLPTVPNGIVIKGSPSEDNVVTYSCRPGYIIQGSSDLICTEKGIWSEPYPTCEPVSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVVDTDTDTFTCQQDGRWFPERINCSPKTCPVPSNRTRIRVHGDDFQVNRQVSVSCTEGFTYDGADRSTCQPDGTWEPPLSEESCIPVVCGQPESPEHGFVVGSEYSFGSTVVYQCDPGYELEGNRERVCQENRQWSGRVAVCRESRCEAPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGPPEAHCTANGTWSHLAPLCKPNPCPVPFVIPENALLSEREFYVNQNVSIKCREGFLLKGNGIITCNPDETWTQTNARCEKISCGPPTHVENAIARGVHYQYGDMVTFSCYSGYMLEGSLRSVCLENGTWTPPPICRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPICILPCLNGGRCVAPYRCDCPAGWTGSRCHTATCQSPCLNGGKCVRPNRCHCLSSWTGHDCSRKRRSGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AVA0-1", "uniprot_id": "SVEP1_MOUSE", "id": "A2AVA0-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "MWSRLAFCCWALALVSGWTNFQPVAPSLNFSFRLFPEASPGALGRLAVPPASSEEEAAGSKVERLGRAFRSRVRRLRELSGSLELVFLVDESSSVGQTNFLNELKFVRKLLSDFPVVSTATRVAIVTFSSKNNVVARVDYISTSRAHQHKCALLSREIPAITYRGGGTYTKGAFQQAAQILRHSRENSTKVIFLITDGYSNGGDPRPIAASLRDFGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQEDMARCSYLCEAGKDCCDRMASCKCGTHTGQFECICEKGYYGKGLQHECTACPSGTYKPEASPGGISTCIPCPDVSHTSPPGSTSPEDCVCREGYQRSGQTCEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTAEMSYNTLCLVTCNEGYRLEGSTRLTCQGNAQWDGPEPRCVERHCATFQKPKGVIISPPSCGKQPARPGMTCQLSCRQGYILSGVREVR-CATSGKWSAKVQTAVCKDVEAPQISCPNDIEAKTGEQQDSANVTWQVPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAITYTATDSSGNQASCTFYIKVIDVEPPVIDWCRSPPPIQVVEKEHPASWDEPQFSDNSGAELVITSSHTQGDMFPHGETVVWYTATDPSGNNRTCDIHIVIKGSPCEVPFTPVNGDFICAQDSAGVNCSLSCKEGYDFTEGSTEKYYCAFEDGIWRPPYSTEWPDCAIKRFANHGFKSFEMLYKTTRCDDMDLFKKFSAAFETTLGNMVPSFCNDADDIDCRLED-LTKKYCIEYNYNYENGFAIGPGGWGAGNRLDYSYDHFLDVVQETPTDVGKARSSRIKRTVPLSDPKIQLIFNITASVPLPEERNDTLELENQQRLIKTLETITNRLKSTLNKEPMYSFQLASETVVADSNSLETEKAFLFCRPGSVLRGRMCVNCPLGTSYSLEHSTCESCLMGSYQDEEGQLECKLCPPRTHTEYLHSRSVSECKAQCKQGTYSSSGLETCESCPLGTYQPEFGSRSCLLCPETTTTVKRGAVDISACGVPCPVGEFSRSGLTPCYPCPRDYYQPNAGKSFCLACPFYGTTTITGATSITDCSSFSSTFSAAEESIVPLVAPGHSQNKYEVSSQVFHECFLNPCHNSGTCQQLGRGYVCLCPPGYTGLKCETDIDECSSLPCLNGGICRDQVGGFTCECSLGYSGQICEENINECISSPCLNKGTCTDGLASYRCTCVKGYMGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGTRCEKNVDECLSQPCQNGATCKDGANSFRCQCPAGFTGTHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGHRCETEQPSGFNLDFEVSGIYGYVLLDGVLPTLHAITCAFWMKSSDVINYGTPISYALEDDKDNTFLLTDYNGWVLYVNGKEKITNCPSVNDGIWHHIAITWTSTGGAWRVYIDGELSDGGTGLSIGKAIPGGGALVLGQEQDKKGEGFNPAESFVGSISQLNLWDYVLSPQQVKLLASSCPEELSRGNVLAWPDFLSGITGKVKVDSSSMFCSDCPSLEGSVPHLRPASGNRKPGSKVSLFCDPGFQMVGNPVQYCLNQGQWTQPLPHCERIRCGLPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSSPVCELVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAAGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLKGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELASEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPICKMVLCPSPPLIPFG-VPASSGALHFGSTVKYLCVDGFFLRGSPTILCQADSTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNATTLCGENGQWLGGKPMCKPIECPEPKEILNGQFSSVS--FQYGQTITYFCDRGFRLEGPKSLTCLETGDWDMDPPSCDAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVLGHAMQTCEESG-WSSSSPTCVPIDCGLPPHIDFGDCTKVRDGQGHFDQEDDMMEVPYLA--HPQHLEATAKALENTKESPASHASHFLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWSGTVPRCEAISCSKPNPLWNGSIKGDDYSYLGVLYYECDSGYILNGSKKRTCQENRDWDGHEPMCIPVDCGSPPVPTNGRVKGEE--YTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVRCPAPPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGTWDAEVPVCKPATCGPPADLPQG--FPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCSTPIIQQGTINATDLGCGKTVQIECFKGFKLLGLSEITCDANGQWSD-VPLCEHAQCGPLPTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVMDSDTDTFTCQQDGHWVPERITCSPKKCPVPSNMTRIRFHGDDFQVNRQVSVSCAEGFTHEGVNWSTCQPDGTWEPPFSDESCIPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLCKPNPCPVPFVIPENAVLSEKEFYVDQNVSIKCREGFLLKGNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLENGTWTPSPVCRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPICILPCLNGGRCVAPYQCDCPTGWTGSRCHTATCQSPCLNGGKCIRPNRCHCLSAWTGHDCSRKRRAGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4LDE5-1", "uniprot_id": "SVEP1_HUMAN", "id": "Q4LDE5-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "MWPRLAFCCWGLALVSGWATFQQMSPSRNFSFRLFPETAPGAPGSIPAPPAPGDE-AAGSRVERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILLHARENSTKVVFLITDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFHIKVIDAEPPVIDWCRSPPPVQVSEKVHAASWDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPSGNNRTCDIHIVIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWKPTYTTEWPDCAKKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDCRLEENLTKKYCLEYNYDYENGFAIGPGGWGAANRLDYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWENQQRLLQTLETITNKLKRTLNKDPMYSFQLASEILIADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDE--YTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG--FPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKRRTGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYR4-1", "uniprot_id": "Q9VYR4_DROME", "id": "Q9VYR4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFCCNIPVDAS-----------VATSTSTSISTYPLQRATKRAMTPPNAMALIMLLLLALCAAGNGQICGPPAVPLNAKVRTIT---------------------------------VDSQIAEAHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQ------SSYTRSGPASYANDG---KPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVH----------VVRITTRGCCGHQPLQDLEIRVGNSSADLQRNP-----LCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSLSLCEVET----FTNDEFSVDRCLSP----KIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTG----------GDLVHDFRGATSSYILSELE------------------------------------RRKSELKPQLVWIGAQKEPGITS---------------------------------RTWKWVNGDVVQKPTWGKDQP---NNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHS------------PLSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHSLLGQTERECRLDGTWS-----------------------------------------------------------GSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDG-WSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGSTATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTTTVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETPSVPSGSFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTN--------------------------------------------TTYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEIRCPEPKLAAHSLLSVTGN--------------------------DRMYGRTLIRTSESSQN----------TAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQP---RCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFLYRNKARPVKNTEN-----------------------------------------------------------------------------------------------------------------------------------------VQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGGAGGRSNGGGNPDANSNGERLNNNR---SENIYDQIP-------------------------NEQFYDAPYEMRTNDEVYEPEPVASNVITINGISVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.:* . :* * . . * * :: * .: : * : .. *. *. * **.. : : : : . :.*: *::*.* :.* . *:: * * . . .: : ::* .. . * : .*:::. .. .:... *. *: :: : :: .* .**. .: .:*. :* * : . * :.:.: . . : *.. : : * :: ::.: . * .* : . :*. *.. .: : . *::* :*: * : .* ..* * ** * :. * : : . : *.* . * :* . :*. : * *.: . . ::. .: * . *:** . **.**.* . ** : *:.* :*.*:*: * :*:.*:*:.. *: .*.*. .* * ** * * . * : ** : .. ** ...* * .: * *. * *. **. ***: **:*: * .* : .:. **: *.*:**: ***:: ** .*.* . .* *: ::* * . .* . ...:.* *:... *:* . * * . *.*. :.* *: : *. *. ...** * ** : * *.* **. : * .: * ::* **:. * * **** * :*. . : : *: * : *. .::* * * *...*..::*.* .*.* * . :.:* .* . :: :. : * . * . ... *. . *.*: ** : * ** :. :*. * *: *:*.:* **:* : : * * .* *:*. *:* :*.** :*.*: * * :* * :.:. .. . .:*:* :* :: * .**.:*.* .: * *:*. ** * : :* : . * :** :*:*:..*: *: *:* :*:***. * * :*. : : .*... * :. : : * *: * . .. . : .. .:. : . :*:.:* . . :. : ..*::. . . . *:*:: :* :..: * :*: * .* ::* *: ... * . ...:: . ", "identical_positions": 259, "similar_positions": 397, "identity": "7.23%" }, { "cls_id": "homologset.agr.MGI:1928858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14533-1", "uniprot_id": "KRT81_HUMAN", "id": "Q14533-1", "name": "Keratin, type II cuticular Hb1", "aln": "MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYR--GLTGGFGSHSVCGGFRAGS-------CGRSFGYRSGGVCGPSPPCITTVSVNES-LLTPLNLEIDPNAQCVK-----QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSN----LEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHIS-----DTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ERE2-1", "uniprot_id": "KRT81_MOUSE", "id": "Q9ERE2-1", "name": "Keratin, type II cuticular Hb1", "aln": "MTCGSGFCGRAFSCASACGPRPGRCCISAAPYRGISCYR--GLSGGFGSQSVCGAFRSGS-------CGRSFGYRSGGICGPSPPCITTVSVNES-LLTPLNLEIDPNAQCVK-----HEEKEQIKCLNSKFAAFIDKVRFLEQQNKLLETKWQFYQNRKCCESN----MEPLFEGYIEALRREAECVEADSGRLAAELNHAQESMEGYKKRYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANAEALTQETDFLRRMYDEETRILHSHIS-----DTSIVVKMDNSRDLNMDCVVAEIKAQYDDIASRSRAEAESWYRTKCEEIKATVIRHGETLRRTREEINELNRMIQRLTAEIENAKCQNTKLEAAVTQSEQQGEAALADARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDVEITTYRRLLEGEEQRLCEGVGAVNVCVSSSRGGVVCGDLCVSGSRPVIGSACSAPCSGNLAVNTGLCAPCG---------------------SAVSCG---RKC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PYS6-1", "uniprot_id": "A0A8M9PYS6_DANRE", "id": "A0A8M9PYS6-1", "name": "", "aln": "MSLSISMASSRMSGGYGGFGAGGGARLGLGLGGGASLGRGLGLGGGLG-YGAGGGFGLGLGGGAGAGAGLALGGGGGGALVASPAFAMGRAVAAGGVGGSSAFAAGPATAAVAPILSRAAEKHTLSGLNDRFSTYMAKVRALQQENAALEAKLSQLTGGADVSPESSVAATVEYEAQLSEYRSTLETLTIDTVKLEIELDNVRGTAHELKAKLDFEQGVKFQLESDIAAMKKDIELASDLRIDLDAKYSSLKDELDYVSKTQEQELSSLQSKLGTSTMDTSVSMIEVDTGKSFDIATALNKMRMEYEKTVQQNREEAEAYYKLKMDEMQTVTAKNTEAVSLTKAEITSARKELQTLSLELQGLAAASMSLEQSLAEAQAQSSVGVAEYQAQIASLTSAIEVAKADLHKQILAYQELLDIKLALDVEISTYRKLLEGDDFKMPEFTETSYTFSGRALPHTSTPQDSPHSPAPKDTQTRYILTAGQIKVKEIITETSVIS-------------------DADDTESS----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . .: . :* . * . : . * * * ** **:* .. *.* * .* ::* .** .**. :* . : . : .* : .* **. :. **.:*:::: *** *:*:* **:* . . ..: :*. :. * * : *: :* **::.: . * : : * .:: *.::.*:***:: * : **:*: .:* :* *:: : ::* *:*::. : ::::*..:.::: : ::: :*:. . :.* ***::*: * :*:::.. :: *:: *: **.. .: :* *: *::. . . .** :::::: *....::: :.::*.* .*:: ** *: : ***::: **.**:**:***:****:: :: * : . . : . : . .. * .. *:: *. : .. .. . ", "identical_positions": 106, "similar_positions": 186, "identity": "20.04%" }, { "cls_id": "homologset.agr.MGI:1928893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97353-1", "uniprot_id": "SEC1_MOUSE", "id": "P97353-1", "name": "Galactoside 2-alpha-L-fucosyltransferase Sec1", "aln": "MPSD-------------SCLLSLT--------VLQRLRAICPPLSTFYLFFVIFVVSTIFHCHRRLGLVPAPWAS----PSLVVFPPRHMPR--EGMFTIRVKGRLGNQMGEYATLFALARMNGRLAFIPASMHSTLAPIFRISLPVLHSDTAKRIPWQNYHLNDWMEERYRHIPGHYVRFTGYPCSWTFYHHLRPEILKEFTLHDHVREEAQAFLRGLQVNGSQPSTFVGVHVRRGDYVRVMPKVWKGVVADRGYLEKALDRFRARYSSPVFVVTSDDMAWCRKSITASRGDVAFAGNGLQGSPAKDIALLMQCNHTVITLGTFGIWAAYLTGGDTVYLANFTQPNSPFHTVFKPEAAYLPEWVGIAADLGQPNTVGSGHASARAPKRHWGALL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAG9-1", "uniprot_id": "F1MAG9_RAT", "id": "F1MAG9-1", "name": "L-Fucosyltransferase", "aln": "MPPETAWDRSTVAPSRLAAWWSRTNWPRRIQAALQGLKAICPPLSTFYLFFVIFVLSTIFHCHRRLSLVPAPWAS----SALVVLSPRHLPR--EGMFTINVRGRLGNQMGEYATLFALARMNGRLAFIPASMHSTLAPIFRISLPVLHSDTARRIPWQKYHLNDWMEERYRHIPGHYVRFTGYPCSWTFYHHLRPEILKEFTLHDHVREEAQAFLRGLRVNGSQPSTFVGVHVRRGDYVHVMPKVWKGVVADRGYLEKALDMFRARYSSPVFVVTSDDMSWCRKSIVASRGDVAFAGNGLQGSPAKDIALLMQCNHTVITLGTFGIWAAYLTGGDTVYLANFTQPSSPFHKVFKPEAAYLPEWVGIAADLEQPNRGAPGHASARAPKSHQRTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q10981-1", "uniprot_id": "FUT2_HUMAN", "id": "Q10981-1", "name": "Galactoside alpha-(1,2)-fucosyltransferase 2", "aln": "--------------------------------MLVVQMPFSFPMAHFILF--VFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLS-------------PLLKH-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:. *:: * ** :*.:***** ::**. : * * . *. . * .**:**.. *************:***:**** *****.***********:****** ** *****:*********.******.****************** ***:************* *****:****:*.*************:************* **::*** ******* :*****:.*:***:.* :*:***.***:*::******:*** *****::*:***************:****:* *.*** .:******:****.****** . * ", "identical_positions": 241, "similar_positions": 57, "identity": "61.01%" }, { "cls_id": "homologset.agr.MGI:1928894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55142-1", "uniprot_id": "RL35A_MOUSE", "id": "O55142-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLI9-1", "uniprot_id": "A0A8I6GLI9_RAT", "id": "A0A8I6GLI9-1", "name": "Large ribosomal subunit protein eL33", "aln": "MRDERKEKNRKTKRRDKKSKVFERGLAESSLSLTFAFWRSTSGLSVERGGACIPQGRAAGLAFLFPPSWRLWRPAGNRTSKKTSMSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18077-1", "uniprot_id": "RL35A_HUMAN", "id": "P18077-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8L2QJQ6-1", "uniprot_id": "A0A8L2QJQ6_RAT", "id": "A0A8L2QJQ6-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWCKAIFAGYKPGLLNQREYTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGVVRAKFQSNLPAKAIGHRIRVMLYPSQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VNB9-1", "uniprot_id": "Q9VNB9_DROME", "id": "Q9VNB9-1", "name": "Large ribosomal subunit protein eL33", "aln": "---------------------------------------MADTQAKSTTAPKAAKAQKAPKAVKAPKAEKPAASEAKVSAKKYKRHGRLFAKAVFTGYKRGLRNQHENQAILKIEGARRKEHGSFYVGKRCVYVYKAETKKCVPQHPERKTRVRAVWGKVTRIHGNTGAVRARFNRNLPGHAMGHRIRIMLYPSRI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41056-1", "uniprot_id": "RL33B_YEAST", "id": "P41056-1", "name": "Large ribosomal subunit protein eL33B", "aln": "----------------------------------------------------------------------------------MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQEAQFYLGKRIAYVYRAS--KEVRG---SKIRV--MWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05744-1", "uniprot_id": "RL33A_YEAST", "id": "P05744-1", "name": "Large ribosomal subunit protein eL33A", "aln": "----------------------------------------------------------------------------------MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRAS--KEVRG---SKIRV--MWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: *. . .*: . :. :::****. :. .**:*** .***:*. . . * ** :****** ***:* *** *. ***.:::* :*::****.*", "identical_positions": 44, "similar_positions": 32, "identity": "22.45%" }, { "cls_id": "homologset.agr.MGI:1928895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA38-1", "uniprot_id": "A0A0G2KA38_RAT", "id": "A0A0G2KA38-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MMGLPEGLRSMADSPEVVAMDCEMVGLGPQ-RVSGLARCSIVNVHSAVLYDKYIQPEGEITDYRTQVSGITPQHMARATPFAEARLEILQLLKGKLVVGHDLKHDFSALKEDMRKYTIYDTSTDMLLWHEAKLHCYSRVSLRLLCKRLLHKSIQN-------------------------------------------------------NWRGHCSVEDARATMELY---------------KISQRLRAQRG---LPCLGTSA----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL16-1", "uniprot_id": "ISG20_MOUSE", "id": "Q9JL16-1", "name": "Interferon-stimulated gene 20 kDa protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------MAGIPEVVAMDCEMVGLGPQ-RVSGLARCSIVNIHGAVLYDKYIRPEGEITDYRTQVSGVTPQHMVRATPFGEARLEILQLLKGKLVVGHDLKHDFNALKEDMSKYTIYDTSTDRLLWHEAKLQYYSRVSLRLLCKRLLHKNIQVLPGSLLGVGGCILPGTDILHLLLYVGMVRIADLRLLTPFLPPSCLACPLLPESLASARSHAVISALSSSSHLLTPLPNPSQGPQGHVDRLSGQLQDWGGSPLAPALPVSAEQLAGPLLCGRCQGHNGALQNLSATQSPARAALPWDVRLNFILIQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AZ6-1", "uniprot_id": "ISG20_HUMAN", "id": "Q96AZ6-1", "name": "Interferon-stimulated gene 20 kDa protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------MAGSREVVAMDCEMVGLGPH-RESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVGATPFAVARLEILQLLKGKLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREAKLDHCRRVSLRVLSERLLHKSIQN-------------------------------------------------------SLLGHSSVEDARATMELY---------------QISQRIRARRG---LPRLAVSD----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RN63-1", "uniprot_id": "A0A8M1RN63_DANRE", "id": "A0A8M1RN63-1", "name": "", "aln": "MSTLLWKHLNSNGVEQNIHTPASVKETSSISHQKKKCKRKKNIKKKNPAIHDTSFEQNRGQKRKLLDNKTECIKNGSTSDFVSEESNNMQFKRPRLTHHTLPGESWEVDSGFSSESSPPTSGRSSPCLRIDHSRIVAMDCEMVGTGPGGRRSEVARCSIVDYYGNVVYDSYILPQDPVTDYRTRWSGIRSHHLRQAVPFEHAQNEILKILKGKIIVGHALYHDLNVLYISVQPHMIRDTCSCVLLRQLYDVNQNCNISLKKLAQKLLNRTIQVD-------------------------------------------------------RQGHCSVEDALSALDLY-------------------KLVEDQWENNILCQDSNAEQSQ--------QFSNNSLKHYLQDQYWPENMMDCSL---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:********* ** * * :****:*: :. *:**.:* *:. :*****: **: .:*: *.** *: ***::****::*** * **:..* .: : * **.: ** : .:. .:**: *.::**::.** .*. :. :: .* :: . ", "identical_positions": 63, "similar_positions": 56, "identity": "14.69%" }, { "cls_id": "homologset.agr.MGI:1928896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PD4-1", "uniprot_id": "ARC1A_RAT", "id": "Q99PD4-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQR---------------------NMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q6-1", "uniprot_id": "ARC1A_MOUSE", "id": "Q9R0Q6-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGNRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQR---------------------NMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92747-1", "uniprot_id": "ARC1A_HUMAN", "id": "Q92747-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWVKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDIPKQSIQR---------------------NMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97182-1", "uniprot_id": "O97182_DROME", "id": "O97182-1", "name": "Actin-related protein 2/3 complex subunit", "aln": "--------MAETYTFGTSLASITCHAWNKDRTQIALSPNNHEIHIYSREGSDWKLADVLNQHDLRVMGIDWAKNTNRIVSCAADRNAYVWTQGDDGKWKPALVLLRINRAATCVKWSPAENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVTSLDWHPNNVLLLAGSTDYKVRVFSAFIKDIE--EPPTPTPWGNRKPLGQLMAEFRNSQTSGGGWINSVSFSSDGNKVCWVGHDSCVSIADATNGNTVIRCRTGYLPFLSCEWVSPTSVVVAGYSCVPLLYSLTADGKLVLSGKLDKSQKKESS---------------------GITAMRIFQSMDRNMRTENTDTVVDSIHQNAITSVRLYAGDKASATKVSTSGVDGQLVIWNVEQGGINGGMRNLQI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38328-1", "uniprot_id": "ARPC1_YEAST", "id": "P38328-1", "name": "Actin-related protein 2/3 complex subunit 1", "aln": "MSFSNSKDKSVVAVYKLVKAPIYSHCFSQDKSILAVTCETDCLVYRVSNNTPPVLFATLKDHDKTITAVDISIHG-RIVTCSQDRNAYVWEPLSDGTYKPTLVLLRINRAATSVTWAPNGYKFAVGSSARIIAVCYYEHENNWWVSKHIKKPIKSTINCLSWHANGVLLAAGGTDGFMRVFSGFIKGLDSKESVAGSPWGQKFPFGCLIREWY-----QGSYIHDVEWRSQMERIAYVAHDGTLNVVDYQSPVQSVNAPEG-LPYRSLVWINDHEIVCGGYSCHPVLFSEASEG-WKFAKNLDKSDNNKSSALTASGNTDELSGNNDESSTFGISALRKFKELDLKGKVS--TDVQESAHENAIVELRPFAESNGQITQVSSCGLDGKIVIYTI---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* .*.:.:*:: :*:: :.. : :.: *::*: : .:* : : ***:*. ******* .** :**:**:******** *.*:* ******.**:*:***:* **:***********:**: .*.**.*.*** **. * ****.:** :: * : :***.: *:* *: *: *.:::.*.: :. .::.:*.**. :.:.* . ** * ::. .:* .*:.* *:*:. * : :** ..:. . .::*:. *:.:* . .. . :: *:*:*..: : .: . :..: *:** :.*: . ", "identical_positions": 114, "similar_positions": 129, "identity": "27.87%" }, { "cls_id": "homologset.agr.MGI:1928897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTP9-1", "uniprot_id": "D3ZTP9_RAT", "id": "D3ZTP9-1", "name": "Piwi-like protein 1", "aln": "MTGR--------ARARARGRARGQETVQHVGAAAQSQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSK------SQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVT-----EVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISV--KPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVD-DRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQ----TVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASIN-EGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVP----QFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMB7-1", "uniprot_id": "PIWL1_MOUSE", "id": "Q9JMB7-1", "name": "Piwi-like protein 1", "aln": "MTGR--------ARARARGRARGQETVQHVGAAA-SQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSK------SQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVT-----EVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISV--KPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVD-DRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQ----TVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASIN-EGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVP----QFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96J94-1", "uniprot_id": "PIWL1_HUMAN", "id": "Q96J94-1", "name": "Piwi-like protein 1", "aln": "MTGR--------ARARARGRARGQETAQLVGSTA-SQQPGYIQPRPQPPPAEGELFGRGRQRG-TAGGTAK------SQGLQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAFDGTILFLPKRLQQKVT-----EVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPNDPIDIPSHRLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKIHQGGKTFDYNPQFADWSKETRGAPLISV--KPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGMQMRKAIMIEVD-DRTEAYLRVLQQKVTADTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQ----TVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGIDCYHDMTAGRRSIAGFVASIN-EGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVP----QFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UVX0-1", "uniprot_id": "PIWL1_DANRE", "id": "Q8UVX0-1", "name": "Piwi-like protein 1", "aln": "MTGR--------ARARSRGRGRGQEPAAPGAQPPVSQEAAKP---VVSTPSEGQLVGRGRQKP-APGAMSE------EAMLQISAGFQQVKIGERGGRRRDFHDSGVHTRQLMEHVKESKTGVSGTAIELRANFMRLLSRPMWALYQYHVDYKPPMESRRLRSALLFQHEETLGKAHTFDGAILFLPNKLRNAET-----VLCSETRNGEKVEITVTLTNELPPSSPVCLQFYNILFRRILRILNMQQIGRHYYNPDDPFNIPQHRLTIWPGFMTTILQYESSIMLCSDVSHKVLRSETVLDFMYSLRQQCGDQRFPEACTKELVGLIILTKYNNKTYRIDDIAWDHTPNNTFKKGD-TEISFKNYFKSQYGLDITDGNQVLLVSHVKRLGPSGRPPPGPAMLVPEFCYLTGLTDKMRADFNIMKDLASHTRLSPEQREGRINRLISNINRNGDVQNELTTWGLSFENKLLSLNGRVLPSERIIQGGRAFEYNPWTADWSKEMRGLPLISC--MSLDNWLMFYTRRNADVAQSLLQTLNKVSGPMGIRMQRAVMIEYE-DRQESLLRALQQNVARETQMVVVILPTNRKDKYDCVKKYLCVDCPTPSQCVVSRTISKPQ----ALMTVATKIALQMNCKMGGELWSVEIPLRQLMIVGIDCYHDTAAGKRSIGAMVASLN-QGMSRWFSKCVLQNRGQEIIDALKGSLQGALKAYLKYNNSLPSRIIVYRDGVGDGMLQSVVDYEVP----QIMQSIKTMGQDYEPKLSVVVVKKRISSRFFARIDGKIANPPPGTVIDTEVTRPEWYDFFIVSQAVRFGCVAPTHYNVVFDNSGLKPDHMQRLTYKLCHMYYNWQGIVRVPAPCQYAHKLAFLVGQSIHKEPNMNLDDFLYYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLK0-1", "uniprot_id": "AGO3_DROME", "id": "Q7PLK0-1", "name": "Protein argonaute-3", "aln": "MSGRGNLLSLFNKNAGNMGKSISSKDHEIDSGLDFNNSESSGERLLSSHNIETDLITTLQHVNISVGRGRARLIDTLKTDDHTSNQFITSESKENITKKTKGPESEAIASENGLFFPDLIYGSKGSSVNIYCNYLKLTTDESKGVFNYEVRFFPPIDSVHLRIKYLNDHKDKLGGTKTFDGNTLYLPILLPNKMT-----VFISKA---EDVELQIRILYKKKEEMRNCTQLYNILFDRVMKVLNYVKFDRKQFDPSRPKIIPLAKLEVWPGYVTAVDEYKGGLMLCCDVSHRILCQKTVLEMLVDLYQQNVEH-YQESARKMLVGNIVLTRYNNRTYKINDICFDQNPTCQFEIKT-GCTSYVEYYKQYHNINIKDVNQPLIYSIKKSRGIPAERENLQFCLIPELCYLTGLRDEVRSDNKLMREIATFTRVSPNQRQMALNKFYENVSNTPAAQEILNSWGLSLTNNSNKISGRQMDIEQIYFSKISVSAG-RSAEFSKHAVTNEMLKV--VHLSKWIIIHLRNYRQAATSLLDNMKQACESLGMNISNPTMISLDHDRIDAYIQALRRNITMNTQMVVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTLQNDL----KIRSVVQKIVLQMNCKLGGSLWTVKIPFKNVMICGIDSYHDPSNRGNSVAAFVASIN-SSYSQWYSKAVVQTKREEIVNGLSASFEIALKMYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYEIP----QFEMVCGNR-----IKISYIVVQKRINTRIFSGSGIHLENPLPGTVVDQHITKSNMYDFFLVSQLVRQGTVTPTHYVVLRDDCNYGPDIIQKLSYKLCFLYYNWAGTVRIPACCMYAHKLAYLIGQSIQRDVAEALSEKLFYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O76922-1", "uniprot_id": "AUB_DROME", "id": "O76922-1", "name": "Protein aubergine", "aln": "-----MNLPPNPVIARGRGRGRKPNNVEANRGFAPSLGQKSDPSHSEGNQASG---GNGGGGDAQVGPSIE-------KSSLSAVQMHKSEGDPRGSVRGRRLITDLVYSRPPGMTS--KKGVVGTHITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHKGILG-GYIFDGTNMFCINQFKAVQDSPYVLELVTKSRAGENIEIKIKAVGSVQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQAKINLENFRMQLWPGYQTSIRQHENDILLCSEICHKVMRTETLYNILSDAIRD--SDDYQSTFKRAVMGMVILTDYNNKTYRIDDVDFQSTPLCKFKTND-GEISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGNDQ-AIMIIPELARATGMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSALVEIPARVLPPEKILFGNQKIFVCDARADWTNEFRTCSMFKN--VHINRWYVITPSRNLRETQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMRSPNEEKYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGAPWQVVIPLHGLMTVGFDVCHSPKNKNKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYFTGH----RNPVPGTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLAFLVAESINRAPSAGLQNQLYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKM1-1", "uniprot_id": "PIWI_DROME", "id": "Q9VKM1-1", "name": "Protein piwi", "aln": "-------------MADDQGRGRRRPLNEDDS--STSRGSGDGPRVKVFRGSSS---GDPR-ADPRIEASRE-------RRALEEAPRR--EGGP-TERKPWGDQYDYLNTRPAELVS--KKGTDGVPVMLQTNFFRLKTKPEWRIVHYHVEFEPSIENPRVRMGVLSNHANLLGSGYLFDGLQLFTTRKFEQEIT-----VLSGKSKLDIEYKISIKFVGFISCAEPRFLQVLNLILRRSMKGLNLELVGRNLFDPRAKIEIREFKMELWPGYETSIRQHEKDILLGTEITHKVMRTETIYDIMRRCSHN--PARHQDEVRVNVLDLIVLTDYNNRTYRINDVDFGQTPKSTFSCKG-RDISFVEYYLTKYNIRIRDHNQPLLISKNRDKALKTNASE-LVVLIPELCRVTGLNAEMRSNFQLMRAMSSYTRMNPKQRTDRLRAFNHRLQNTPESVKVLRDWNMELDKNVTEVQGRIIGQQNIVFHNGKVPAGEN-ADWQRHFRDQRMLTTPSDGLDRWAVIAPQRNSHELRTLLDSLYRAASGMGLRIRSPQEFIIYDDRTGTYVRAMDDCVRSDPKLILCLVPNDNAERYSSIKKRGYVDRAVPTQVVTLKTTKNRS-----LMSIATKIAIQLNCKLGYTPWMIELPLSGLMTIGFDIAKSTRDRKRAYGALIASMDLQQNSTYFSTVTECSAFDVLANTLWPMIAKALRQYQHEHRKLPSRIVFYRDGVSSGSLKQLFEFEVKDIIEKLKTEYARVQLSP-PQLAYIVVTRSMNTRFFLNG----QNPPPGTIVDDVITLPERYDFYLVSQQVRQGTVSPTSYNVLYSSMGLSPEKMQKLTYKMCHLYYNWSGTTRVPAVCQYAKKLATLVGTNLHSIPQNALEKKFYYL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:. . . . : . * * : : *.::: . : :*.: : * :: ::* * :* :* *** :: : . :: . .: : *. *::: * :. :: ..* ::* : :: :***: *:: ::: .::* :: *::: :*: ::: :: . . ::. ::** ***:**:::*: : .* *. *: :*: :. * * :* :: * ::**:. **: :* : . :: :: .**:.*.:* : : : . * *.:.: . .. .* : :.* . *:: .. ::. :..* :: . ::: :. : :.: . ** : :.: :.:::: : . . ::* .:** : . *:* : :. : ::. *:.:*:*.*: * : :*: * *:* :. .: ..::*::: . ::* : : : : : **: : : :* .::.:***:..* * .: *: :: ::: ::* : :.:* * ** ***::* :* .: ***::*** ** * *:** * *: .. . .: :* *:**: .:***: * *:** * **:*** *:. .:: *.. :::*", "identical_positions": 128, "similar_positions": 265, "identity": "14.32%" }, { "cls_id": "homologset.agr.MGI:1928898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMA1-1", "uniprot_id": "UBP14_MOUSE", "id": "Q9JMA1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 14", "aln": "--MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKMKN-GMTVLMMGSADA-LPEEPSAKTVFVEDMT-EEQLATAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMAS-----AQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQG-QYLQQDANECWIQMMRVLQQKLEAIEDDSGRETDSSSAPAVTPSKKKSLIDQYFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMVSFRSKFKDLEDKK--------------------------VNQQPNANDKNSPP-KEIKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVRRKQDE--WIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EK08-1", "uniprot_id": "F7EK08_RAT", "id": "F7EK08-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "--MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKMKN-GMTVLMMGSADA-LPEEPSAKTVFVEDMT-EEQLATAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMAS-----AQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQG-QYLQQDANECWIQMMRVLQQKLEAIEDDSARETESSSASAVTPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMISFRSKFKDLEDKK--------------------------VNQQPNANDKNSPP-KEIKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKEDE--WIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEDSEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54578-1", "uniprot_id": "UBP14_HUMAN", "id": "P54578-1", "name": "Ubiquitin carboxyl-terminal hydrolase 14", "aln": "--MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKN-GMTLLMMGSADA-LPEEPSAKTVFVEDMT-EEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMAS-----AQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQG-QYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKK--------------------------VNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDE--WIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKZ8-1", "uniprot_id": "Q9VKZ8_DROME", "id": "Q9VKZ8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "--MPAFKVKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDDQW-NLQIKD-GAVVLLLGSKES-VPEVPATPVKFIEDMN-EAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVPELRTALSTFS--NDGTDTMST-----AFSISSAMKSIFAQMEKG-TTVTPIVLLQALHRASPQFAQTGENG-TYRQQDANECWAEILKMLQQKLRPKNQEP---------SNTVQKRHSSFIDQFFGGTFEVKMSSEEDPDEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSETLGRDAKYIRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPELQNKLCPMRSKFKDLEDKK--------------------------MEVDVVKRNEPNEEKKDVKYEQFWFDDDLGSNNSGYYTLQAVLTHKGRSSSSGHYVAWVRSSGDV--WFKFDDDEVSAVATDEILRLSGGGDWHCAYVLLYAPRRLEKL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43593-1", "uniprot_id": "UBP6_YEAST", "id": "P43593-1", "name": "Ubiquitin carboxyl-terminal hydrolase 6", "aln": "MSGETFEFNIRHSGKVYP-ITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEESIKIYPLIKPGSTVMLLGTPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGFYKQQDAEELFTQLFHSMSIVFG------------------------DKFSEDFRIQFKTTIKDTANDNDITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKEREIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILMYKGFGL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...:: . : : : :.** . :*:: ** * . *** * *** ::. : . * .::::*: :: : . *: *:**: * : .** *:.*:*****:***:*.: * :*: : : :. : : : : :* .:: **:**: *: . ****: ..:* * ****:* : :::: :. : . :.: * *:..:. . :: . .*. :*.*.*. .::: .** ::*:: *:* :: * :**** :**:* *** :* . . ::*:*:.: **: :* :: *** : .*.:::.:*.:* : : :. . : : * : *.* . * * .*:**:* .*.**** :::: . * * **:**:** * :.* *:***: . * :*:* : ", "identical_positions": 117, "similar_positions": 162, "identity": "21.95%" }, { "cls_id": "homologset.agr.MGI:1928899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K598-1", "uniprot_id": "A0A0G2K598_RAT", "id": "A0A0G2K598-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NRKTLCFPQEDAVSYNTVLWPPNPDPPQRTSSVQSLRSLQPPGNSQ-TPQKQGDSPGS-------GAASTGLGASCSASESVASLDPSTVSPEVTKPGEHPQEARD--PEDSPLPRSSLPWEQPYPSASMPFTEGLSEGCLANSEAEVPEDGPLTNHLRVEPSPNGPGDILLTFTPEVDGPAQRTVAARTPSAEGDQELKEEGQSSSSSCTG---QSPGISFVPLQEPKTELLYGKGDWPRDFEFQRKDDIDNCSSPESVT---------KAPAATQPGMQN-----------------------------SAVLE-CPPKLETMVPQDSVLRSSDSKKGRSEVLPMDLAKHVEFLGGCHPSKGNSGANPGAGTSPASQESCQLRVGMPLPSAELPSGPQGLTTARADGGSWEETLDTSSAQSQPQTGTSGAEPQQVVCVPAASQPGGSLLLSAKAPGFTGTEERHTASSPTARLTAWSSTASEEPT----EAVSETKMSVSADLAATGQMGPGVVELKPTSDLRRTQEQPPEGSCLQWVPAPFLQG------RNDTIQEG-------------LLLPPFS----------------HQVSNESSRRSMGPTDDPKASKNTENRVVAREESIPHGDNRKGQQEATRALAGTELRNHDKEKSHAFRAKPRGDTEKDDISEL-----------------------HSNKENKIVPSSDSTQPPRQEVA--------ESHMTDTATSLHEVHEEDPILSSASDGTGEHFLPQDAIWESSRLQTESSVMLQARGGLE---------------------------------------------ATESLPVLESEKADALPATAMEEEAPRAAEMEDVLEVKKDHSPLHQPYSCAGQGLPMSPGQPCGLEKVEPGQEDHADTSSPPNGKNSTIGDG-------------------------------------LTVPRLEQDGQRKLSCP-------EASLPPPLQN--PLLSSQLDPDAAISAVLCDKDQSPTNGQRACLCGPGLKEQSTDPSPIPVSEEGKPWADVSLSTQGGKE--QGSELP---SKGSLCDTPSSSPKGTVLGGAPS---------------------------------------------------------------------EMSELSTPLGQELPALGGNEQENTGRNSQPSEIQPPSA------SLTGH--------------------------SGGKDSFCVGQGLSKSQQELADALQTGSQREEARCGDSGISEATGVLPPPRG---LEKIETASRNIAEAPPGPPDSVALLDTAYCSPDPVPTNPGVAPAHDALVSEACDESQKE-----SVPQLDMEQRATLGPEEQSPLGSFRRAEEQDSKEGSAEVSVDAS-------------DGDPKMQQASEAP-EAALSSGFFQADQSLP-------STLKEPRQPAKLEPSCGDALLPAGESNGIPRSTVGVLTHRAVSGPQSLLPAEPPEETVPDTPYLHISGAAKKDAEDASMRAVFSEDPGAPHESPI---KEPPPVENDTPGKSPAVSFTTDLQPGTAHGEISVAGDGDGIPQAGTTEGHVSLTPYLDRMPLLVRDEQVAREMHVAATPETNARPSETAVCPASEEAAGETGGSRERAVELTPDLMVVTSGSEGASSKQPSVIKGLPDF-------REHITKIFEQSVFGALAADRTHSVPSKKSGVPSSMLVEGPVISLDSGKLPDGVQGMAAAPLPVPPVGLQVEKKQESG----------------------VKAEVSHPVPQDPAPEKLMGLAEAALEESLPGAIVEGEVTRVPLTVTSERLE---GTGEPGQGAQ----------AHTQQARSRQELVVGLPSSKAVQGVPAEPAPGFPVDPQSHADADEASSQGDKSHSVKEYLETLPSNSPHGINGAQDSVHTKGPSNLLGSTCALDGSSPHGSVLNMPESNSEPWIPSTLGGERQLEAAVCTSDKQNVLENQDGP-------KMLAREVLAIPLGPSNMAGAAEEAEGDVTPSRPETWAEVSGDLLETGTTRMLPHEAGDSAPPGSYRDSGCSNRTQVMEDTATLPGDSQVGCQQAKEPLGPQ-------------------------------------LPAPYGKTSVSSPPEPDESSDEKLHLLAPEVL-TDRKSPGPGSATSPSVLEIHAPKGSSAETRDLGG----------------------------------------------AESTSPSAAHASLAPVASEHAALASAAAGPGVET-PTASCQHLAKNINRSSDSEE------AFETPESTTPVKAP------------------------PAPPPPPPEVTPEPEVIEPPAPE------------------------------------------------------------EPGCISEP-VVVPDGPRS-ESVEGSPFR-PSHSSSAVFDEDKPIASSGTYNLDFDS------------------IELVDNFQSLEPCSADYKGQECKVSTRRKSTESVPPSKTTLSRSLSLQASDFDGASCPGSPEAGTLATDACGTGSNSASSTLKRTKKTRP----PSLKKKQATKKPTETPPVKETQQEPGEESPVPSEEHLAPETKTESATPE------GTGCTLSEETSLESAAVPTATCPLTLESVEDVSPLVSGGGRVQNSPPVGRKSVPLTTASEAVEVTLPDGGG---------QEDLPAKGLSVRLEFDYSEDKGSWESQQENAPPTKKIGKKPVAKMPLRRP----KLKKTPEKLDNTPASPPRSPAEPSDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPT-LSQQSYNFDPDACEESLDPFKASSKTPSSPSKSPASFEIPASTIEAD--------GDGLNKPAKKKKTPLKT------------DTFRVKKSPKRSPLSDPPSQDPTPAATPEAP--------------------PVSTVVHATDEEKLAVTS-QKWTCMTVDLDADK--QDFPQPSDLSNFVNETKFNSPSEGKQLSGQPDPHLALENTDPRGQRPRKDSCQPELDYRNSYEIEYMEKLGSSLPQDDDTPKKQALYLMFDTPQESPVKSPPVRMSDSPTPCSGSSFEDTEALVNATAKLQHPVPRGLASNQEPLLQLPEKSSQKELEAMALGTPAEAIEITAPEGAFASADALLSRLAHPASLCGALGYLEPDLAEKNPPVFAQKLQEELEFAVMRIEALKLARQIALAS------------------------------------------RSRQDTKREATHPPDVSISKTTLYSRIGPTEVEKPPGLLFQQPDLDSALQVARAEVIAKEREVSEWRDKYEESRREVVEMRKIVAEYEKTIAQMIEDEQREKSISHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKKCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAYQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJG0-1", "uniprot_id": "TACC2_MOUSE", "id": "Q9JJG0-1", "name": "Transforming acidic coiled-coil-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNENSTSDH-----------------------------------QRTSSVQSPRS-----------------------LQ---------PPGKSQSLQKQQG---------------------------------------------------DLPGSCAG-----------------------------------------------------------SIPGTDDVIQPAAPVDPGHPPLAGIGSNQGE----------------------------------------------------------------------------VCTS-------------------------------------------------------------------------------------------------------------------------------------------------------------LQLSYTIVTVQS--------------------------------------------------------------------------------------------------------ASPSAARASPAPLAPEHTASAPSAAGPGVEVTPTGSPQHLAKNEPRSSDSEE------AFETPESTTPVKAP------------------------PAPPPPPPEVTPEPEVIDPPAPE------------------------------------------------------------EPGCISEPPVVVPDGPRSSESVEGSPFR-PSHSSSAVFDEDKPIASSGTYNLDFDS------------------IELVDNFQSLEPCSADSKGQECKVSTRRKSTESVPPSKSTLSRSLSLQASDFDGASCPGSPEAGTLTTDACGTGSNSASSTLKRTKKTRP----PSLKKKQATKKPTETPPVKETQQEPGEESPVPSEEHLAPETKTESATPE------GAGCTLSDDTPLESPAVPTATCPLTLESAEDVSPLVSGGGRVQNSPPVGRKSVPLTTASEAVEVTLSDSGG---------QEDLPAKGLSVRLEFDYSEDKGSWESQQENAPPTKKIGKKPVAKMPLRRP----KMKKTPEKLDNTPASPPRSPTEPSDTPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LSQQSYNFDPDACEESLDPFKASSKTPSSPSKSPASFEIPASTTEAD--------GDGLNKPAKKKKTPLKTMVEDVMSVCSLFDTFRVKKSPKRSPLSDPPSQDPTPAATPEAPS-------------------AISTVVHATDEEKLAVTS-QKWTCMTVDLDADK--QDFPQPSDLSNFVNETKFNSPSE-------------------------------ELDYRNSYEIEYMEKLGSSLPQDDDTPKKQALYLMFDTPQESPVKSPPVRMSDSPTPCSGSSFEDTEALVNAATKLQHPVARGLPSSQEPLLQVPEKPSQKELEAMALGTPAEAIEITAPEGAFASADTLLSRLAHPASLCGALGYLEPDLAEKNPPVFAQKLQEELEFAVMRIEALKLARQIALAS------------------------------------------RSRQDTKREAAHPPDVSISKTALYSRIGSTEVEKPPGLLFQQPDLDSALQVARAEVIAKEREVSEWRDKYEESRREVVEMRKIVAEYEKTIAQMIPGTER-KILSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKKCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAYQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95359-4", "uniprot_id": "TACC2_HUMAN", "id": "O95359-4", "name": "Transforming acidic coiled-coil-containing protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNENSTSDN-----------QRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARG--PEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLAS-PAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTES-----------------------------SAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPG-------------VPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKP-----------------------SSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLG---------------------------------------------RMESFLTLESEKSD-FPPTPVAEVAPKAQEGESTLEIRKMG-------SCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLG-------------------------------------LTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVE--PQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLT---------------------------------------------------------------------EESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGN--------------------------FSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWG---LSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAG-------------AGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAG---DAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDF-------REHIAKIFEKPVLG------ALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLA----------------------GEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQ----------AYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIP---SGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAP---SPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTP-------APPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERP-----------------------------------IPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEA-STPSCPDPAKDLSRSSDSEE------AFETPESTTPVKAP------------------------PAPPPPPPEVIPEPEVSTQPPPE------------------------------------------------------------EPGCGSET-VPVPDGPRS-DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN------------------IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP----PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTE------GPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGG---------QEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP----KMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANG-----VDGDGLNKPAKKKKTPLKT------------DTFRVKKSPKRSPLSDPPSQDPTPAATPETPP-------------------VISAVVHATDEEKLAVTN-QKWTCMTVDLEADK--QDYPQPSDLSTFVNETKFSSPTE-------------------------------ELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALAS------------------------------------------RSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T2R9-1", "uniprot_id": "A0AB32T2R9_DANRE", "id": "A0AB32T2R9-1", "name": "", "aln": "MSESVWPPQSSCQLTAYTPSSLNLPSYLYPARTLCGYRNKFTSRLKKRQACLLWSSFNKQTLKLYVNRDLDKCTTSISVSWAAVHTDKVSPPKEKSAATENGSVHPESITAETQVTADEEEKPGRQGEEDKEELEFPHDLLPSLDLDLSTELNLTWGTTLGEQVSLGDMKNETVALGGTANPLLAGLEHYMEASSPVVGLMKSCDGDQVSTESASLTQVHLPSTPQQDVPSLNPLVRVDYELQEAFKECEDEMAALGKSSIIDTWTAGDLNKCFPLVLPGRDEKTEQTKMSEVKEDSFDSSSHKLAEFHQGCHGNDGAHTNDSTAGEEGVFSFRDYVLGKDLGNMCTAESKDVRNIKNITENPREESSQLSEAEQQTKSIIEPKIDTAESIAVQQTTHSTWTGTQTASEKDVAKEALTPDQSIQDACNSKCSLDDVVGLSETVAIKEANLVNKYVINSATATQMIENAEMHSQMISDLLPCPSTHMDKHAGDTWDSEAKISVQPNIQKQVESGTRQQISEEIKTKTNVGSSLENQKQELQLPEQLCREDKQLMWSPPSVLEVHQAHLTLADNLSAKILHPLQGLQQHDDQDQTDGPYKSISVVETIYHCTTGEVKHEKNVSDASAVVIDFCKAKTDSEYEPKGRCDLEKQPPEQENGPLLGGGAGTHAPVWGNSHSPSRARTEEEEEEESALERASAESAASTLLQTTPTMPEMIESEGEKKRDDAFQSAAIIVQAAERESAVLDTDESPSSEGTLSEITAEEGQECTLLIFPKIKCSPVQIEETTEESCGNKIAPKKSTENEKKGGGLPTALFLAGDKDTGTVSTEDKAAVTCSSPGILGTCDWKVESSLSKEKKGESEKEEKETSEGGAENAAHAGRVSQTETVKETCPSHRITASQTAPEDRSDFIHPVTTGTALFPLTINRINDCDSISPPPPLSLINSTEAEAQREDKANQNSSPSASGAELPGSDLLLPPANSSKSESLAVQANNQQVQSALQTKSANCDTSIKTESQQQKQETILTREDTSQSTNLQENMRDITGCCTKMEGHLPSKGLQSSFKDQKDAALTCQMTECASLPPLMVFESLRHPVKEASFNFVGFLSISKAELPSQTEPEVAQRTTVLDAIAEEESSVKNETSQEECKGEENCQQIAKVEQEEIKSEKPKNCTETTSQEQGEATVNPEENVYVNMGGCEESGKVTDETPDASKSNPVKFSSLSTADETAGVTETKDVGNETREEIKAIKEEEEYKEALNTTQISHNESASSEKNSVLLQDVSEQEGHNCSLAVDLVHADNAVSAKVEQINQIEETDETKGYGLPEAGGIETKFPNNSKNLVNDSQGKQSKYTCEEGSEVKTSLLPQTAVLDADSTYQDKNFTTEQPTETSEMPLLPKVDTYADVEPCQTESQFSAEMMKSDGMDAEDEAVPSLTAVEITVPAQRDLSSSTTQSTNSVARDVSVIVLKAPGPMLSHCESISDCDIAVAETREHCSVKCVCESDPEIVKNIADKTNLDANEDMLSKQNANHPPYTVGASAQETAASSGSLLLTTDRPEQAGGSLLMSKKPDIVGNTKMKENEEFNDTVQLKIVREEKRKANANSKLEDNSCKAPTSVISDDEVVNKDTSEGRQVKREEHNNNCAKDTQEKASSKQEESISQEDGNEQKNMEQDRWKEQEEMAFRELKDSREKTNTSEVPCADKMLHSQITLIKQQTPKDDIICDSLLMPLEDKLGTRMSEEPVQRVSVDNVKIKTNLSEAFRQGMSEEKNKECVQEHENSITENDSKECTNNSQKQDESVKENMDQTRGENQTLMKLFEIPEENLINETIPKGKFLSSSVPDSGVIFKGTIEKTVDHSGPPTEKSLPVIDQTSVALRQSDLAFPQSQELQQQQMFISAPEAVLSLGKSCALKNAETNNHADADASEKQEKVTVYCSAEAKSSPDSTSESAELVEGHHRDFNVDSICPQNEDLSIPTKELRGEKSHVCGESTLSETQTQPAPNLPVNAVSGSETSEFKRVIKALEVKQFVISASQESVNKHADCSNSQVSADEYGNVWNKTLATKKGAELPVSHSSGLSASPSVLHYEEGIKTDEHYLDFVTPGDTGNTEIRPDSVSEVAQMSAAEPSQLQQEKELIFQPSDAQCSSDTARFSATALEESIKEEKEISVDQASKDALKPNAPNSTPESETAAWRMEQLNKHLSEQFPDGTQNTEKQHTLCSEKQLTQLQHAVTCSGTENQIGTMKAEDTFSNDRQEPQGIQEETSKQINETAEKCHMELSKGTGPNLSENVGKESMSKENQSKVEAHSLSASEESIVCNVDQPIEIATDGVLIEMDQVVSLLCPETASCVVTYPQDCLQPPFTVNQQSIEQHKSSSDTLKSGSEEHPEIANSSPANAKAIQKDDSEASEEKVNMVSQAADDGLLGSGPGAVQVKDSTDTQTDSTDSANFVPERSNKVNSSEGSDWLRVLKEAASMSQVIPEHKDETTCGSTDNRPFESFGSPQAELEFRTPTGEFLPPAPEESFPPGPEETFPPAPEDSFPPGPVESFPLASEDTFPPAPEDNFPPPPEESFPPVPEEIFPPAPEESFPLVTEQPEEASDCRSPLLEAAEWSEPVPSPSSLPPQHSFAPALPAHLLQDTLEFPTPPPTPPDRAPAEPQTFPPAPDPSDLPQISPDFPLPPPVQQLQHSEPSARSSDSDGAFETPESTTPVKSVSPSVPPTEHPYTSSETLSPKHTASSSDVPASEGEDPSLHRSPSRSDSTAFDEDKPIAASGTYNLEYLISNDPFPESNFGSGSSRAPLTRSQSLQSGELESPGNKSPGISDKPIHPRTESFNIGTESAPGTLRRVKKPRPGSLKKKPLSRQNSNPERSSPKTVSSSSTPEQKKRGKPRPESPLQTQDKPSSSPSPSPSPAGTLRRNRGKSQVESSPPLAEEITTTSISAQPLLELPDPVPEASTVPDEESPILPSASYKWDPDNFENINPFSTGGSKIANSPVLGRKADFTSVQDTPAALEQPRAPSPAKAQPLNVEEQPIPNRQPVRLEFDYSEDSG---EASRSTPPPKNLGKKPGAKMPIRKPKLGIKKAPPPQMEQIDNAPLPALSNDNDDIPIPKASYNFDPSKWEDPNFNPFSSNTGIPNSPG-LSKGSYSFESDSFDGSISPFKSSSKIGNSPPKG-ASFDQTSNDNENDNDHIVELEDHNQNKPAKTKKKPLKS------------NTFRVKKSPKRTQIPDPPAQVSQDCCPVCSPLSPTTSHTHHHLQEHSPDADPDPSQDHATDEEKLASSTNQKWTRHDVEVELTSGPQDFPQPTDFTAFVNENSFS------------------------------------QSDVTDYEIEYMEKIGSSAPP--LSGKKPSLYLKLDSVTESTKSTSNMNDSEPNSPCTG-SFEEMEAQISQGKSPVLPPRGTREP------MTSDKSRKRDSQSQSRTQSNERDGASPIQGPMDPSD--LPLLDRLSDSPAPLSYLEPDLAETNPTAFAQKLQEELVLAALRIEALQVAKNISQSPTLSTVSPQSRLKKPSPRLWNINGSHMAKTAVKSTQTDRKLCRRTSRIPQTEIASPGDSSVSKGSLYSRTGYIEGESP----HLPRDMDHSLGIAREEIVVKEKEAMEWKRKYEESRREVEEMRRIVMEYEKTIAEMIEGEQREKSVSHHTIQQLILEKDQALADLNSVEKSLADLFRRYEKMKDVLEGFRKNEDVLKKCAQEYLSRVRKEEQRYQALKIHAEEKLDKANSEIAQVRAKAKQEQAAHQASLRKEQMKVDSLERTLEQKNKEIEELTKICDELIAKMGKS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4JD97-1", "uniprot_id": "A0A0B4JD97_DROME", "id": "A0A0B4JD97-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFLANIIKRPKSIATTGISTN------------------------------------------------------------------------------------------------------------------------------QPTTMEALEAASPADECSTPRDKGGVTLVSAHLDSLLESASEELQRLEGKHCELFMESISNPLPAPEDSTDSREEIQKFLSEINFNLNQVSANEMEHLQAMSGELSPLAVKPSPKPTSMDQQKAMAAALGHQTAVPGGLKPEDDLVPKFGGLPEFDETQIPELAPLSTDMDTQLKSNHSDSDVFVECLSLHSERYTGDRSELEAYSSALNDVLEQQLSMTS-------------------------------------------------------------------------VSTLGAEFNDPLAVS---------------------------------------------------------------------------------------------------------------------QHNNVSYEAMDVDDLNETMEMLKDVLNAEDR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLMQTHILSVTQ--------------------------------------------------------------------------------------------------------SKPENNFVHYHPNQEQNRVELDQLAKHSKPNSDAKESESLVESVLSEESGTQS------FEPKLTLSALDST------------------------KDLAKHQEEMQTNTKDIFQKEKHHP----------------------------------------------------------VSSAQVKDAQNPKEPEKALNLKEASSELSTKSAKSLEYPNQEKQFSVAVESMERPC-------------------TAISLEQNASPAMEATEDRTVEELDQMDVDESMKVDDATVLNSCRQEQINAHSPVSSKFFLKLCVQNDTDCQDNKMDQKTAGKESALKMTEIELPVESVPSASLSPPTPALQAKIIELSLSPPIPTHRPKTAEELEFLALRELP-----LPDGVSTAGKVECKQLSHGLVPIVAVLPTPLYLDLKGNTTTASLPEPTSPSFPIKEPAEKQSHFPR-----------------SPRAQLEQKDMPYLEEAVVERSSHRKQSDFGVIAKSP-IVFELTQP-------SPEKQHLNETLPMSEISPTSSNMTFDSGSITEDKSQKGTENIEPSSTLAVSLGSVDDKQRRTFSVVQPTKEEEEAKSRRTFCMENENPRRTFCMQQNASPAVEATEDTGADEVMDVDISMRADEVAVMKS---------HQQTWKERQAPISNSPPIPTHQRLNRPPEAISPVS------------------PLGNGTVVLEEQTLSAKEQATLSASDEKDDVFLEHFGAISPVSDDMFKTSSASNN-----------------------------------QAKFRVNADEETGGKGASAMIRKRSGTAGEQEEIFDAEFHDGVNNQNLILNSS----------DFDYLYTKGSNSVPIDRSSLLLKFDPLLGAPVPVNHPNQQEQALQN--------ILGSNQHQNRLLSPTLEEHETSDGNQSFGVISSAKDTAKKWDFKPPVDRTKKHVKMSVDVIDNDCNKTFD-----------------------------------------NSNTNTEDKTHNYNDMDELEKKIKNEVTRSE------------DIEKKLKEG-------ELREEALIKRITEKDKTNAKLNGVIEAYEKAIAELISEKEQQAQLHERQLQEVQADRDANYHHLTSLETTFSDLHVKYEKSKEMTSQLKSNEESLLAERKQMMDNLRLQEQRYDKMKNHAMQQLEIANKKLDTYSREHADETKKLKALLKKEEISRVSMTEQLQQKSRENADLLKICEELIYGKGQGGSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .. . . : . . * * :: : .. :*. .: :. . : . . . . : : : * .. : * : ::: : .. .:: . *. . :. . :*. . : : .. : . ..* : . : . .:. .. :*. . . .. : : : * : * . . : .*. . * : . .. : :: * *: . .. . :.*.* : : :* . : . . . .: .: ..: . * .: *::* *: : * : ::.. : : . : : .. .: .:: :. . : . : .: .: . :*:: :::* . . *. * :* . :*:.*: . . : . : . .* . * ... . * *:* : . :*: .. .. : ... : : . . . : : : . . . * . . .: . *: .. : * : :::.. : .: : .: .: : * . : : .. * *:: * . * . : *. : ::. :: ***:**::* :: : .: :*:: ::: .*.*:*.:::**. :*** *:: . ::.**: * :: :..:: :****: :* ** ::*: ** :: : :* :* *:**:: :: . *:**.:* :* ***:*** *:. ", "identical_positions": 91, "similar_positions": 303, "identity": "2.37%" }, { "cls_id": "homologset.agr.MGI:1928900", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R491-1", "uniprot_id": "EHD3_RAT", "id": "Q8R491-1", "name": "EH domain-containing protein 3", "aln": "MFSWLGNDDRRKKDPEVFQTVSEGLKKLYKTKLLPLEEYYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDVEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEETQRPVQMVKGGAFEGTLQGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPPSKRKVAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXY6-1", "uniprot_id": "EHD3_MOUSE", "id": "Q9QXY6-1", "name": "EH domain-containing protein 3", "aln": "MFSWLGNDDRRKKDPEVFQTVSDGLKKLYKTKLLPLEEYYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDVEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEETQRPVQMVKGGAFEGTLQGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPPSKRKVSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZN3-1", "uniprot_id": "EHD3_HUMAN", "id": "Q9NZN3-1", "name": "EH domain-containing protein 3", "aln": "MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.****:**********:*******:*******:*****************************************************************:**************************************.***************************************************************************************************************************************:*********************************************.***************************************************************************:***:************:*******************************************************************************:*******************.**************:*", "identical_positions": 520, "similar_positions": 15, "identity": "97.2%" }, { "cls_id": "homologset.agr.MGI:1928901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5T2W1-1", "uniprot_id": "NHRF3_HUMAN", "id": "Q5T2W1-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "aln": "MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILSPVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGSEQK-----GQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQE--------------------LPNGSVKEAPAPTPTSLEVSSPPDTTEEVD-----HKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLAD---------PLDTPPDSKEG---IVVESNHD-SHMAKERAHSTASHSSS------NSEDTEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8MUH7-1", "uniprot_id": "PDZ1P_HUMAN", "id": "A8MUH7-1", "name": "Putative PDZ domain-containing protein PDZK1P1", "aln": "--------------------------------------------------------------------------------------------------------------------------MNGGVQTWTQPRLCYLVKEGGSHGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGSEQKGWGRVGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQE--------------------LPNGSVKEAPAPTPTSLEVSSPPDTTEEED-----HKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLAD---------PLDTPPDSKEG---IVVESKHD-SHMAKERAHSTASHSSS------NSEDTEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJ40-1", "uniprot_id": "NHRF3_RAT", "id": "Q9JJ40-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "aln": "MASTFNPRECKLSKKEGQNYGFFLRIEKDTDGHLVRVIEEGSPAEKAGLLDGDRVLRINGVFVDKEEHAQVVDLVRKSGNSVTLLVLDGDSYEKAVKHQVDLKELDQSPREPALNEKKPDLGMNGGVETCAQPRLCYLVKEGNSFGFSLKTIQGKKGVFLTDITPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQKTPFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQK-----GQIIKDIEPGSPAEAAGLKNNDLVVAVNGESVEALDHDGVVEMIRNGGDQTTLLVLDKEADRIYSLARFSPLLYCQSQE--------------------LPNGSVKEAPAPISAPLEAPGSATTEDVGD-----HKPKLCRLIKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENEDIIIEVNGENVQDEPYDRVVERIKSSGEHVTLLVCGKVAYSYFQAKKIPILSSLAD---------PLVAGPDAKGETEHDSAESTKDSSHPARDRTLSAASHSSS------NSEDTVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIL4-1", "uniprot_id": "NHRF3_MOUSE", "id": "Q9JIL4-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "aln": "MASTFNPRECKLSKQEGQNYGFFLRIEKDTDGHLIRVIEEGSPAEKAGLLDGDRVLRINGVFVDKEEHAQVVELVRKSGNSVTLLVLDGDSYEKAVKNQVDLKELDQSQREAALNDKKPGPGMNGAVEPCAQPRLCYLVKEGNSFGFSLKTIQGKKGVYLTDIMPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQKTQFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQK-----GQIIKDIEPGSPAEAAGLKNNDLVVAVNGKSVEALDHDGVVEMIRKGGDQTTLLVLDKEAESIYSLARFSPLLYCQSQE--------------------LPNGSVKEGPAPIPAPLEATGSEPTEDAEG-----HKPKLCRLLKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENEDVIIEVNGENVQEEPYDRVVERIKSSGKHVTLLVCGKMAYSYFQAKKIPIVSSMAE---------PLVAGPDEKGE---TSAESEHD-AHPAKDRTLSTASHSSS------NSEDTEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QTX0-1", "uniprot_id": "F1QTX0_DANRE", "id": "F1QTX0-1", "name": "", "aln": "-MAGPKPRIISLTKRESQGYGFYLRVEHGEEGHLIRALEMGGAAELAGLKDGDRILRVNNTFVDNLEHTQVADLVRNSGMSVTLHVLGEEAYKTAKANNVNLADLQSLPGQS-------QPTMNGVSTPAAKAKLCYLQKSSSGFGFSLKSTKGAHGIFMVDVVSGGVADQAGVKLGDRLVEINSENVEHLVHDQIVQKVKAASDRLMLLLVDEEADRYFKSKNIQPGVSHATVKHLPHKPRIADMIKRADGYGFMLKEDPKRK-----GHCIGEIDKGSPAERAGMKDMDRLAAVNGEDIENCKHEQVVEKICQG-NKCCLLVLDAETDKIYKLGGVSPLLYWEEMRGSLPGYPDNEAVAIPAVAAAVPAAVVAATPAPAATPAPAATPTPVPAAAEPADVDHKPKLCRLERTSAGFGFHLNGIQGVPGQHIQEVVKGGAADRAGLVDDDVVVEVDGVNVEMSTHEEVVNLIRNSGDTLVLLVADRKAYEHLKAKGIPITPQLLNKEPAADVPAPAYTQVDGRKD-TEKDIEKPATPPAPTRSRSSSSSSSSSSSSSASDDSEDERL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** . ::.:**** *.....*****: :* :*:::.*: . *** :*** .*:*:*:*.****. *:::*:**. :..*:*:****:*: : . .:: . *::* ***:**:. : * ::**** *: ..::* *: * :*: ***** **:*: * :.****:.:* .*: *** * :* :: ***:* *:: :* *. .**:** :. . :* . * *** .:. .. . . ******** : . .:*****.*:* **..::** :**.** *** ::*:::**:* ** ..::.**: *:.**. :.***..: **.:::** *** ..: : * : * : *. . ::.*: *::* *** :*** :", "identical_positions": 153, "similar_positions": 143, "identity": "26.94%" }, { "cls_id": "homologset.agr.MGI:1928902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL2-1", "uniprot_id": "CNOT9_RAT", "id": "Q5PQL2-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTA-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQV-LKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKY0-1", "uniprot_id": "CNOT9_MOUSE", "id": "Q9JKY0-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTA-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQV-LKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92600-1", "uniprot_id": "CNOT9_HUMAN", "id": "Q92600-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTT-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQV-LKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWL4-1", "uniprot_id": "CNOT9_DANRE", "id": "Q6NWL4-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-------------------------------MLATGATVSTAGLAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVTDLAPMLWHSCGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHVETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNSRAREALRQCLPDQLKDTTFAQV-LKDDSTTKRWLAQLVKNLQEGQVTDPRGIPLPTQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLF2-1", "uniprot_id": "Q9VLF2_DROME", "id": "Q9VLF2-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-------------------------------MSAEPSPVMSP-QQQAER------------------------------------------------------EKVYQLIIELAYPATRETALLELSKN--TYADLAPMLWKSVGTTCTLLQEIVNIYPIIT-TPVLKANQSNRVCYALTLLQCVASHPETRPAFLRDQIPMYLYPFLSTTFKSRPFEQLRLTTLGVINALAETGDTEVLIFLIWSEVVPHCLTNMVRGSKLTKIAATSILEKILLDEMGLTYICENHDRFSQVAITLGKMVIHMLK-FPCLRVLKHVVRCYLLLTENARARSALRVCLPDLLRDGTFTSL-VQHDTCTKQWLQMLLKNLQTNAVN-PMGSS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53829-1", "uniprot_id": "CAF40_YEAST", "id": "P53829-1", "name": "Protein CAF40", "aln": "MFSAQKPIYGNGAGVNMGGGGPSTNNPGSMSMPGVPTSMGPGMNQQIPSGGPMLMGNTPNNNNSNENGENNGNNGNNGGNDANATRNNPNMVNNRGAVHALDDPNVYHWICQLTYGPQKEQALLELGRKREQFDDLAVVLWSSFGVMTSLLNEIISVYPMLQ-PQMLSNNLSNRVCNALVLLQCVASHPETKHLFLQAHIPLFLFPFLNTTSRQRTFEYLRLTSLGVIGALVKNDSQDVITFLLRTDIVPLCLRIMESSSELSKTVAIFILQKILLDDVGLQYICATLERFYAVTNVLKDMVEHLTVSTPPGRLLKHIIRCYLRLSDDLEARRLLKIVLPAKLRDNTFTEV-LRDDVGSKRCLAQLLLTLNEETS-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V9S3-1", "uniprot_id": "Q9V9S3_DROME", "id": "Q9V9S3-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "---------------------------------MSAPNMDCEQRGDIDS--------------------------------------------------------VFGWIANLCNKETRLWAMLELFERRTHIDSLGLLLWHSFGAVSGLLQEIVSIYPAIYQEIELTGQQSHRICTAIGLIQAMASHPFIGIQLIRCQFMCYLMPLLKMTSQTRAVEHVRLSVLGVICGLLKSDHPEIVSYFLGTELIPLTLRQLEFGTTMSKVLCAFVLYRTLEHEVGLKFASRRLARKLHLIHTLARVVHQLTL-EPEPRVLKHVVRIYSRLADHPQNLELILKLLPAQIRNGYFCQEGLVGFESASLELADLNRKLSKNEEKDKVCDDAMPENH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :: * :* : *:*** .. .*. :** * *. **:**:.:** : *. : *:*:* *: *:*.:*** :: :: :* *:* . : *..* :**: **** .* :.. ::: ::: ::::* * : .: ::* . :* : * .: ** : . * : * :* :: * *:***::* * *::. . : ** ::: * . : :. * * .*. ", "identical_positions": 63, "similar_positions": 86, "identity": "16.24%" }, { "cls_id": "homologset.agr.MGI:1928903", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95473-1", "uniprot_id": "SNG4_HUMAN", "id": "O95473-1", "name": "Synaptogyrin-4", "aln": "MHIPKSLQELANS------------EAVQFLRRPKTITRVFEGVFSLIVFSSLLTDGYQNKMESPQLHCILNSNSVACSFAVGAGFLAFLSCLAFLVLDTQETRIAGTRFKTAFQLLDFILAVLWAVVWFMGFCFLANQWQHSPPKEFLLGSSSAQAAIAFTFFSILVWIFQAYLAFQDLRNDAPVPYKRFLDEGGMVLTTLPLPSANSPVNMPTTGPNSLSYASSALSPCLTAPKSPRLAMMPDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z1L2-1", "uniprot_id": "SNG4_MOUSE", "id": "Q9Z1L2-1", "name": "Synaptogyrin-4", "aln": "MHLPESLHDLADN------------ETVRFLRRPKSISRIFGGVFSLVIFSSLLTDGYQNRTESPQLRCVLNSNHMACSFAVGAGFLSFLSCLVFLAIDAYERRLVGTRFKIAFQLLDFILAVLWAGVWFVAFCFLASQWQHSKSKHFLLGNSSAKAAIALSFFSVPVWILQAYLAFQDLRDEAPVPYKRSLEEGSVVLNTLS-PSSTSPSNPPITGPNSLSYTSSALSPYMTTPKAPRLAMMPDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7JYV2-1", "uniprot_id": "SNG_DROME", "id": "Q7JYV2-1", "name": "Synaptogyrin", "aln": "MDMLNQILSINNGGAYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWTEKDGKE--YCLYNGDGMACKYGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSSAPPPLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPANVVHQQAYGYSMDND---NDQYSASPFGQPQQGGMEQQQSGMEYQQPTY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: :.: .: :. :.: * :*: : * : :**:::*..: ::*: :: . *: *.: :**.:. .*.:.**:.: *: : *: ..: : : : *: ::.**: ::*:.* :* .**. * . : :* .* ::** : :**: * : * :*:: : * :. :: . : . . : .. * * ... . : :: * ", "identical_positions": 39, "similar_positions": 96, "identity": "15.85%" }, { "cls_id": "homologset.agr.MGI:1928904", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKB1-1", "uniprot_id": "A0A8I6GKB1_RAT", "id": "A0A8I6GKB1-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPASRMLRQLLRSNVRSCS--------SGAPMTQPRPGEPSRPTREGLSMRLQFLQEHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCRYCMPEEGVSLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVARLHQLEGLRTIGVTTNGINLARLLPSLQQAGLSAVNVSLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYKPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDAIRQRWPGLEKLPEEDSSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEEELLRIIGVAVGRKKRQHAGMFNIAQMKNRPMILIG-----VLLMLQD-------------------SPPASWSTLSWDPLHVR----------------------------NPGAKQCLSDQMATLWKRHSVPMALPLSQQCLGSGSPQRHYSSYPDPD---------THPKCLSTGS---------------------RAPDVPSGPGPTSDQLTHVDSAGRATMVDVGGKPETERVAVASAMVLLGPKAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIPLCHHVALSHVQVHLELDSTRHAVLIQVSCRARGPTGVEMEALTSAAMAALTVYDMCKAVSRDIVVTEVKLISKTGGQRGDFHRT-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RKZ7-1", "uniprot_id": "MOCS1_MOUSE", "id": "Q5RKZ7-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPAFGIVRQLLRSNARGCS--------SGAPVTQPRPGEPSRPTREGLSLRLQFLQEHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVARLHGLEGLRTIGLTTNGINLARLLPRLQQAGLNAVNISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYKPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTIRQRWPGLEKLPEEDSSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEEELLRIIGAAVGRKKRQHAGMFNIAQMKNRPMILIG-----VLLMLQD-------------------SPPARWSNFSWDPLRVR----------------------------NPSARQCLSDQMASLWKRHCIPKALPLSQQCLGSGSPQRHYSSYPDPD---------THSKCLSTGS---------------------QAPDAPSGPGPTSNQLTHVDSAGRASMVDVGGKPETERVAVASAMVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIPLCHHVALSHVQVHLELDSTRHAVLIQASCRARGPTGVEMEALTSAAMAALTVYDMCKAVSRDIVVTEVKLISKTGGQRGDFHRA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZB8-1", "uniprot_id": "MOCS1_HUMAN", "id": "Q9NZB8-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPLSRMLRRLLRSSARSCS--------SGAPVTQPCPGESARAASEEVSRRRQFLREHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGIDKIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWPELEKVPEEESSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEQELLRIIGAAVGRKKRQHAGMFSISQMKNRPMILIE-----LFLMFPN-------------------SPPANPSIFSWDPLHVQ----------------------------GLRPRMSFSSQVATLWKGCRVPQTPPLAQQRLGSGSFQRHYTSRADSD---------ANSKCLSPGS---------------------WASAAPSGPQLTSEQLTHVDSEGRAAMVDVGRKPDTERVAVASAVVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKVTSQLIPLCHHVALSHIQVQLELDSTRHAVKIQASCRARGPTGVEMEALTSAAVAALTLYDMCKAVSRDIVLEEIKLISKTGGQRGDFHRA-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ79-1", "uniprot_id": "A0A8M3AJ79_DANRE", "id": "A0A8M3AJ79-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "MALNCNTFSRIIFGAHTAAEACVKFCRPVQQACGRYQMCRWYSGVTHEENRLEEVREPVVPGGHRR---VLKDVLPFSQFLTDSFGRRHNYLRISLTEKCNLRCQYCMPQDGVKLTPRSQLLTTHELLTVARLFVQEGVNKIRITGGEPLIRPDILHIIAELRKLEGLKTIAVTTNGMNLAKILPDLKKAGVDLLNISLDTLVPAKFEFITRRKGFHKVMEGIERAIEMGYNPVKVNCVVMRGLNEDELVDFVSLTERKPLDVRFIEYMPFNGNRWNFKMMVSYQEMLDCIKQKWPNLQPLPGEETDTAKAFQIPGFQGQMGFITSMSDHFCGSCNRLRITADGNLKVCLFGNAEVSLRDFLR-SGATEKELLHIIGAAVGRKKKQHAGMLNISKMKNRPMILIGRDCTWLLPMSPFRDNQRQTLPLIHRMDLAAISTTQSLGKCNHRPFHVIGYQDYKSTFVTDALYSFYSLTRFTNRKQNRKALEALCNDRISKSYRVTVSASKQNKSRMLLQHILQKHSRPPVPQSKIFALIPFLSTSRALLKDSALQFARHCHHKTPECGFHLKIRHKDLKSSLDGTSNQLTHTDAQGKASMVNVGAKAVTRRTATACGKVILGPKAFNLVCANQVAKGDALAVAQLAGIMGAKQTSNLIPLCHPLPLDHASVTIELLEEEHAAVIKATCQTTGRTGVEMEALTAVSIASLTLYDMCKSVSHDIIITDVKLLSKTGGQRGDYHL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQF1-1", "uniprot_id": "MOCS1_DROME", "id": "Q8IQF1-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "----------MRLLARHAIRLLGQENSAGEVASLS-------RGAIRLKATTGYLNLATASVQPLE---PEKQVLRKNSPLTDSFGRHHTYLRISLTERCNLRCDYCMPAEGVPLQPKNKLLTTEEILRLARIFVEQGVRKIRLTGGEPTVRRDIVEIVAQMKALPELEQIGITTNGLVLTRLLLPLQRAGLDNLNISLDTLKRDRFEKITRRKGWERVIAGIDLAVQLGYRP-KVNCVLMRDFNEDEICDFVEFTRNRPVDVRFIEYMPFSGNKWHTERLISYKDTLQIIRQRWPDFKALPNGPNDTSKAYAVPGFKGQVGFITSMTEHFCGTCNRLRLTADGNIKVCLFGNKEFSLRDAMRDESVSEEQLVDLIGAAVQRKKKQHA-------------------------------------------------------------------------------------------------------------------DAAPRLHHHLHPYSYHHAYHT----------------SRLQLQAR--------------------------------NYSQLTHVDGQGKAQMVDVGAKPSTTRLARAEATVQVGEKLTQLIADNQVAKGDVLTVAQIAGIMGAKRTAELIPLCHNISLSSVKVQATLLKTEQSVRLEATVRCSGQTGVEMEALTAVSVAALTVYDMCKAVSHDICITNVRLLSKSGGKR-DFQREEPQNGIVTEVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : . .. *. : .. . :.. . *******:*.********:***** **** :** * *: .****.*:* :**:**::*: ***:***** :* *::.*:*.:: * *. *.:****: *:::* *::**:. :*:***** :** *.****:.:*: **. *:::**.* *****:**.:****: **. :*. *:**********.**:*: : ::**:: *: ::*:** :: :* ..*:**: :***:**:.*****::****:*****:*****:******* *.**** :* ..:*::*: :**.** ***:*** : : * :: . .: . .****.*. *:* **:** *. * * * * . * :* :*: **: ***.*.***:**: .** *::****** :.*. .* * . .::. ::.: : * *********:.::*:**:*****:**:** : :::*:**:**:* *:: ", "identical_positions": 245, "similar_positions": 165, "identity": "32.67%" }, { "cls_id": "homologset.agr.MGI:1928939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VMA4-1", "uniprot_id": "Q9VMA4_DROME", "id": "Q9VMA4-1", "name": "HotDog ACOT-type domain-containing protein", "aln": "----------MNLSQHFG--------------RRVIAVRHPWHQLGAIRHSFMESGRELLDSGHRSG--TMADVAKKIREHVGVEGGYHIIP---KSRDGLLKFQPK-QDELPNRSMLDSQTTAQVLLETDALLRQRFVYGRGLLRMGRIIEELDLLAVWICHLHIHLPNLPEGVPLPYTFITMLVDHAHFL-QDKFIADADVSLSGHVSYTDNNFMEVTAYVRQ-------SG----MLLAKGIFVVEARDAINNGPAPVNPLVPANELEESLHQEAQKRHQER-AKALYRLESQQPTKEEQQLMYELFTRTKGDDGPSPSDMTTLPPNSRWMSTWRRRTLMHPFPENRNESNTIFGGFIIRKAIEISYMTASLYSNQRCMIRFIADVTFAHSIPVHSYIKLKAYVVFTHENYIQLLTVVNAIDGNSFTELKCNVLHLTYSCSKAVPEILPRSYHEALWYLTGRRYFNRFRESVSHDMDNGSAVETNGAKKDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9W4-1", "uniprot_id": "Q9V9W4_DROME", "id": "Q9V9W4-1", "name": "HotDog ACOT-type domain-containing protein", "aln": "--------MLCTLARSFGTALARRSSWSTARRRRLLATSPPPLASQQMPRSYTLDNGPKVKSDHRSG--TMVEVARVIREQSGVDVGYHTIP---KPRDHLLQHEPK-REELPPRTMLDSHTTAILPLSSSELIRESYVNHLGRVRLGRIMEELDMFAVWICHRHVKLPKLPKGVPLPYTFVTLLVDKVEFTNLERLQVNQDIEISGHISWAGRSSMEITIYVRQ-------LAHGEYIDVTKAIFVMVARNATNTGPAPINPIEVGDETEKLIWEQAEKRQKVRKSSAMDSVFNSPPREHEQALMYEILKRTTPAN-SMDLNKRVLPPKCRWMEDSMQSTMIAPFPENRNAQNTIFGGYLMRQAVEISFIMASIYLGDRPTLRCISDISFMHPVHVDRFLQLTAHVVYAAQNYVQLMTVAQIWDAKSGKVQTTNVFYLTYRADKVLDEVLPRSYREMLWYVHGRRKLLGALHLQPEYPDPIEVAKESSNHIST", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9W5-1", "uniprot_id": "Q9V9W5_DROME", "id": "Q9V9W5-1", "name": "HotDog ACOT-type domain-containing protein", "aln": "MGPGLRNVKLCVVPFLLG--------------ARSCRSLLKARTLRKMTHKNSSSNGRNSSADGQYA--TMTEIKKKMLKSFGLEPGFTTEP---KSREDLLKYQPK-FEDLPARSMQDSFCSAIIPLSTNAVLQDKYINFRGFARLGRLLEDMDIFAAWCCNRHLKVPNLPEGVPLPYSLVTVLVDRIDFT-SVSPQGTQDIRLSGHVSWVGTSSMEVVVWLEQ-------IVNEEYQKITRALFLMAARNATNTAAAPVNPIQPANEEEKRILAGGTDRKKQRQLLIAQSVFKVEPNAEEQSLIYKLYKRTTPNEQTGPR--RLLPPNCIWMHDSFQMSTIPSFPEHRNQNNTVFGGFLMRSALEISWATAFLYCKARPTLEHISDISFQKPVSVNSFIKMTAYVVYTQENYLQIMTVAEVLDAYTGNHVTTNTFHYTFSAPDAVTEVLPRSYHETMWYIHGRRKFIASRS---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F7ETS0-1", "uniprot_id": "F7ETS0_RAT", "id": "F7ETS0-1", "name": "", "aln": "--------------------------------MKRAAMRLWTLNKGLLTHGRGLAYGSEN-KICKP--LHIQEVRNKLREIVGVSTIWRDHVKAMEERKLLHNFLATSQKALPPRKMKDSYIEVLLPLGSDPDLRDKYLTVQNTVRFGRILEDLDSLGVLVCYMHNQNHSTKM---SPLSIVTVLVDKIDMC-KYSLSPEQDIKFTGHVSWVGKTSMEVKMKMFQSSYSFHMHSDDKFWPVLDATFVMVARDSENKGPAFVNPLVPENKEEEELITQGELNKSRRIAFSTTSLLKVAPNSEERNVIHELFLNT-LDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNIFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQDNYIQVRVHSEVASLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVILKKNYTVEP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0X4-1", "uniprot_id": "ACOT9_MOUSE", "id": "Q9R0X4-1", "name": "Acyl-coenzyme A thioesterase 9, mitochondrial", "aln": "--------------------------------MKRAAIRLWTLNKGLLTHGRGLSQGSQY-KISEP--LHIHQVRDKLREIVGVSTVWRDHVKAMEERKLLHSFLPKSQKVLPPRKMRDSYIEVLLPLGTDPELRDKYVTVQNTVRFGRILEDLDSLGVLVCYMHNHNHSTKM---SPLSIVTVLVDKIDMC-KHSLSPEQDIKFTGHVSWVGNTSMEVKMKMFQ------LHNDEKYWPVLDATFVMVARDSENKGPAFVNPLIPENKEEEELFKQGELNKSRRIAFSTSSLLKVAPSSEERNIIHELFLTT-LDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNVFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQDNYIQVRVHSEVSSLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVTLKKDYPVEP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y305-1", "uniprot_id": "ACOT9_HUMAN", "id": "Q9Y305-1", "name": "Acyl-coenzyme A thioesterase 9, mitochondrial", "aln": "--------------------------------MRRAALRLCALGKGQLTPGRGLTQGPQNPKKQGI--FHIHEVRDKLREIVGASTNWRDHVKAMEERKLLHSFLAKSQDGLPPRRMKDSYIEVLLPLGSEPELREKYLTVQNTVRFGRILEDLDSLGVLICYMHNKIHSAKM---SPLSIVTALVDKIDMC-KKSLSPEQDIKFSGHVSWVGKTSMEVKMQMFQ------LHGD-EFCPVLDATFVMVARDSENKGPAFVNPLIPESPEEEELFRQGELNKGRRIAFSSTSLLKMAPSAEERTTIHEMFLST-LDPKTISFRSRVLPSNAVWMENSKLKSLEICHPQERNIFNRIFGGFLMRKAYELAWATACSFGGSRPFVVAVDDIMFQKPVEVGSLLFLSSQVCFTQNNYIQVRVHSEVASLQEKQHTTTNVFHFTFMSEKEVPLVFPKTYGESMLYLDGQRHFNSMSGPATLRKDYLVEP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E6M3-1", "uniprot_id": "A0AB40E6M3_DANRE", "id": "A0AB40E6M3-1", "name": "", "aln": "------------------------------MFCPRFLKAAVSFTCRKFSMGQISRQGKTLDMAE---------VRNRLREVVGASTNWQDQQQVLSERSSLCQYLARSQDDLPAKRMKDSLIEAHLPLGSQPALREKYLNSHNSVRFGRILEDLDCLGVLICYSHTWNEELQS---SPLSIVTALVDKIDMR-QNVIYPDCDIKFTGHVTWVGKTSIEAKMHMSQ-------YQNGTYADLLDATFVMVARDPDNKRAAFVNPLKPVGQEEEAIFLQGEINKKRRVELSTASLLKVAPTAEERTLIHNQFLNT-LDTRTVSFRSRILPPNSVWMEDAKLKGLEICHPQERNIFNRIFGGFLMRKAYELGRANACAFAGCRPTVVAVDDILFRKPVEIGSLLLLSSQVCYTEGMYVQVRVHSEVLDPLTRQHSTTNVFHFTFRLEKEVPAVVPQSYGESMLYLDGKRHFDGAMRNHS------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1R961-1", "uniprot_id": "F1R961_DANRE", "id": "F1R961-1", "name": "", "aln": "------------------------------MLSPRVLKSASSLMCRGFSMGQMCRQGKAPDMADGNTFLLVSNVRNRLREIVGASTNWRDHQQALAERASLTQYLANSQDELPTKTMKDSAIEAHLPLGTQPALREKYLNYHNSVRFGRILEDLDSLAVLICYSHTWNKELQR---SPLSIVTALVDKIDMR-KNIIYPDCDIKFTGHVTWVGKTSIEAKMHMSQ-------FHDGVYSDVLDATFVMVARDPENKRAAFINPLKPEGPEEEAIFQQGEINKKRRVELSTASLLKVAPTAEERTLIHNQFLNT-LDTRTVSFRSRILPPNSVWMEDAKMKGLEICHPQERNIFNRIFGGFLMRKAYELGWANACAFAGCRPTLVAVDDILFRRPVEIGSLLLLSSQVCYTEGMHVQVRVHTEVLDPLTRQHSTTNVFHFTFRVDKDVPAVVPQSYGESMLYLDGKRHFDETMRGQS------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : * . : * * .. . . ** : * ** . : * :. ::: :: . *:**::*::* :.. * * . * :::* ***: .: *: ::**:::.. . :* : * : . *:: **:. *. .* :**: . *: : . .: * : . * .*: ::: * . **.:. ** .*:.** * :***:::*.* *:. * : * : : *: * :.: : : :.: * :: ::*: . : . . *.:: *: . : :.*::* * : *: *:* : ", "identical_positions": 66, "similar_positions": 119, "identity": "13.36%" }, { "cls_id": "homologset.agr.MGI:1928940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ETS0-1", "uniprot_id": "F7ETS0_RAT", "id": "F7ETS0-1", "name": "", "aln": "--------------------------------MKRAAMRLWTLNKGLLTHGRGLAYGSEN-KICKPLHIQEVRNKLREIVGVSTIWRDHVKAMEERKLLHNFLATSQKALPPRKMKDSYIEVLLPLGSDPDLRDKYLTVQNTVRFGRILEDLDSLGVLVCYMHNQNHSTKM---SPLSIVTVLVDKIDMC-KYSLSPEQDIKFTGHVSWVGKTSMEVKMKMFQSSYSFHMHSDDKFWPVLDATFVMVARDSENKGPAFVNPLVPENKEEEELITQGELNKSRRIAFSTTSLLKVAPNSEERNVIHELFLNT-LDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNIFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQDNYIQVRVHSEVASLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVILKKNYTVEP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32MW3-1", "uniprot_id": "ACO10_MOUSE", "id": "Q32MW3-1", "name": "Acyl-coenzyme A thioesterase 10, mitochondrial", "aln": "--------------------------------MKRAAMRLWTLNKGLLTHGRGLSQGSQY-KISEPLHIHQVQVKLREIVGISTVWRDHVQAMEERKLLHSFLPKSQKVLPPRKIRDSYIEVLLPLGTDPELRDKYVTVQNTVRFGRILEDLDSLGVLVCYMHNHNHSTNM---SLLSIVTVLVDKIDMC-KHSLSPEQDIKFTGHVSWVGNTTMEVKMKMFQ------LHDDETYWPVLDATFVMVAQDSENKRPAFVNPLIPENKEEEELFTQGELNKSRRIAFSTSSLLKVAPSSEERNIIHELFLST-LDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNVFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQGNYIQVRVHSEVFSLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVTLKKDYPVEP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y305-1", "uniprot_id": "ACOT9_HUMAN", "id": "Q9Y305-1", "name": "Acyl-coenzyme A thioesterase 9, mitochondrial", "aln": "--------------------------------MRRAALRLCALGKGQLTPGRGLTQGPQNPKKQGIFHIHEVRDKLREIVGASTNWRDHVKAMEERKLLHSFLAKSQDGLPPRRMKDSYIEVLLPLGSEPELREKYLTVQNTVRFGRILEDLDSLGVLICYMHNKIHSAKM---SPLSIVTALVDKIDMC-KKSLSPEQDIKFSGHVSWVGKTSMEVKMQMFQ------LHGDE-FCPVLDATFVMVARDSENKGPAFVNPLIPESPEEEELFRQGELNKGRRIAFSSTSLLKMAPSAEERTTIHEMFLST-LDPKTISFRSRVLPSNAVWMENSKLKSLEICHPQERNIFNRIFGGFLMRKAYELAWATACSFGGSRPFVVAVDDIMFQKPVEVGSLLFLSSQVCFTQNNYIQVRVHSEVASLQEKQHTTTNVFHFTFMSEKEVPLVFPKTYGESMLYLDGQRHFNSMSGPATLRKDYLVEP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E6M3-1", "uniprot_id": "A0AB40E6M3_DANRE", "id": "A0AB40E6M3-1", "name": "", "aln": "------------------------------------MFCPRFLKAAVSFTCRKFSMGQIS-RQGKTLDMAEVRNRLREVVGASTNWQDQQQVLSERSSLCQYLARSQDDLPAKRMKDSLIEAHLPLGSQPALREKYLNSHNSVRFGRILEDLDCLGVLICYSHTWNEELQS---SPLSIVTALVDKIDMR-QNVIYPDCDIKFTGHVTWVGKTSIEAKMHMSQ-------YQNGTYADLLDATFVMVARDPDNKRAAFVNPLKPVGQEEEAIFLQGEINKKRRVELSTASLLKVAPTAEERTLIHNQFLNT-LDTRTVSFRSRILPPNSVWMEDAKLKGLEICHPQERNIFNRIFGGFLMRKAYELGRANACAFAGCRPTVVAVDDILFRKPVEIGSLLLLSSQVCYTEGMYVQVRVHSEVLDPLTRQHSTTNVFHFTFRLEKEVPAVVPQSYGESMLYLDGKRHFDGAMRNHS------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMA4-1", "uniprot_id": "Q9VMA4_DROME", "id": "Q9VMA4-1", "name": "HotDog ACOT-type domain-containing protein", "aln": "----------MNLSQHFG--------------RRVIAVRHPWHQLGAIRHSFMESGRELLDSGHRSGTMADVAKKIREHVGVEGGYHIIP---KSRDGLLKFQPK-QDELPNRSMLDSQTTAQVLLETDALLRQRFVYGRGLLRMGRIIEELDLLAVWICHLHIHLPNLPEGVPLPYTFITMLVDHAHFL-QDKFIADADVSLSGHVSYTDNNFMEVTAYVRQ-------SG----MLLAKGIFVVEARDAINNGPAPVNPLVPANELEESLHQEAQKRHQER-AKALYRLESQQPTKEEQQLMYELFTRTKGDDGPSPSDMTTLPPNSRWMSTWRRRTLMHPFPENRNESNTIFGGFIIRKAIEISYMTASLYSNQRCMIRFIADVTFAHSIPVHSYIKLKAYVVFTHENYIQLLTVVNAIDGNSFTELKCNVLHLTYSCSKAVPEILPRSYHEALWYLTGRRYFNRFRESVSHDMDNGSAVETNGAKKDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9W4-1", "uniprot_id": "Q9V9W4_DROME", "id": "Q9V9W4-1", "name": "HotDog ACOT-type domain-containing protein", "aln": "--------MLCTLARSFGTALARRSSWSTARRRRLLATSPPPLASQQMPRSYTLDNGPKVKSDHRSGTMVEVARVIREQSGVDVGYHTIP---KPRDHLLQHEPK-REELPPRTMLDSHTTAILPLSSSELIRESYVNHLGRVRLGRIMEELDMFAVWICHRHVKLPKLPKGVPLPYTFVTLLVDKVEFTNLERLQVNQDIEISGHISWAGRSSMEITIYVRQ-------LAHGEYIDVTKAIFVMVARNATNTGPAPINPIEVGDETEKLIWEQAEKRQKVRKSSAMDSVFNSPPREHEQALMYEILKRTTPAN-SMDLNKRVLPPKCRWMEDSMQSTMIAPFPENRNAQNTIFGGYLMRQAVEISFIMASIYLGDRPTLRCISDISFMHPVHVDRFLQLTAHVVYAAQNYVQLMTVAQIWDAKSGKVQTTNVFYLTYRADKVLDEVLPRSYREMLWYVHGRRKLLGALHLQPEYPDPIEVAKESSNHIST", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9W5-1", "uniprot_id": "Q9V9W5_DROME", "id": "Q9V9W5-1", "name": "HotDog ACOT-type domain-containing protein", "aln": "MGPGLRNVKLCVVPFLLG--------------ARSCRSLLKARTLRKMTHKNSSSNGRNSSADGQYATMTEIKKKMLKSFGLEPGFTTEP---KSREDLLKYQPK-FEDLPARSMQDSFCSAIIPLSTNAVLQDKYINFRGFARLGRLLEDMDIFAAWCCNRHLKVPNLPEGVPLPYSLVTVLVDRIDFT-SVSPQGTQDIRLSGHVSWVGTSSMEVVVWLEQ-------IVNEEYQKITRALFLMAARNATNTAAAPVNPIQPANEEEKRILAGGTDRKKQRQLLIAQSVFKVEPNAEEQSLIYKLYKRTTPNEQTGPR--RLLPPNCIWMHDSFQMSTIPSFPEHRNQNNTVFGGFLMRSALEISWATAFLYCKARPTLEHISDISFQKPVSVNSFIKMTAYVVYTQENYLQIMTVAEVLDAYTGNHVTTNTFHYTFSAPDAVTEVLPRSYHETMWYIHGRRKFIASRS---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : * . : . *. * .. . . ** : : ** . : * :. ::: :: . *:**::*::* :.. * * . :::* ***: .: *: ::**:::.. . :* : * : . *:: *::. *. .* :**: . *: : . .: * : . * .*: ::: * . **.:. ** .*:.** * :***:::*.* *:. * : * : : *: * :.: : : :.: * :: *:*: . : . . *.:: *: . : :.*::* * : *: *:* : ", "identical_positions": 64, "similar_positions": 123, "identity": "13.01%" }, { "cls_id": "homologset.agr.MGI:1928947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET20-1", "uniprot_id": "SCAM4_RAT", "id": "Q9ET20-1", "name": "Secretory carrier-associated membrane protein 4", "aln": "-------------------------------------------------------------------------------------------------------------MAGKE----------NNFPPLPHFLPLKPCFYQDFSDEIPVEHQVLVKRIYRLWMFYCTTLGVNLVACLAWWIAGGAGANFGLAMLWLVLFTPCSYVCWFRPAYKAFRADSSFNFMAFFFIFGAQFVLTVIQAIGFSGWGACGWLATIGFFG-TSVGAAVVMLIPAIMFSLSAVVMA--ITIVKVHRIYRGAGGSLQKAQTEWSAGTWRNPPSREAQFNSFSGNSLPEYPTVPSYSTSGSQWP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKV5-1", "uniprot_id": "SCAM4_MOUSE", "id": "Q9JKV5-1", "name": "Secretory carrier-associated membrane protein 4", "aln": "-------------------------------------------------------------------------------------------------------------MAGKE----------NNFPPLPPFLPLKPCFYQDFSDEIPVEHQVLVKRIYRLWMFYCATLGVNLVACLAWWIAGGAGANFGLALLWLVLFTPCSYVCWFRPAYKAFRADSSFNFMTFFFIFGAQFVLTVIQAIGFSGWGACGWLAAVGFFG-TSVGAAVVMLVPAILFSLSALVMA--VTIVKVHRIYRGAGGSLQKAQTEWSAGTWRNPPSREAQFNSFSGNSLPEYPTVPSYSSSGGHWP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969E2-1", "uniprot_id": "SCAM4_HUMAN", "id": "Q969E2-1", "name": "Secretory carrier-associated membrane protein 4", "aln": "-------------------------------------------------------------------------------------------------------------MSEKE----------NNFPPLPKFIPVKPCFYQNFSDEIPVEHQVLVKRIYRLWMFYCATLGVNLIACLAWWIGGGSGTNFGLAFVWLLLFTPCGYVCWFRPVYKAFRADSSFNFMAFFFIFGAQFVLTVIQAIGFSGWGACGWLSAIGFFQ-YSPGAAVVMLLPAIMFSVSAAMMA--IAIMKVHRIYRGAGGSFQKAQTEWNTGTWRNPPSREAQYNNFSGNSLPEYPTVPSYPGSG-QWP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXV6-1", "uniprot_id": "Q9VXV6_DROME", "id": "Q9VXV6-1", "name": "Secretory carrier-associated membrane protein", "aln": "MSGSGLDENPFGEPNLDNPFADPAIQQARRLQSGAALVSLEDYNPFEEQAKPQLQINSTNTAAVVQPLSQNIPPPQTSSLGASAPSTSIQITSEELQRRQEELDRKAAELDRREQQLQGNVPQLNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLILLFHAGEFETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFNKMGYCGFITAIGQFDGQASGIIVGILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQAEFTTEFLRNQHVQEAASSAVN-TAINSQFNNSRY--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* **:**** : :******:*. *** *.* ****:* :*:** ** .*::. * : .* .* **:.: :**:*..*******.***** *******.****: * : :::**:**. * **:::::* * : * * :*: : *..:* :* : * *:* ***.:*.*: ***:*:.: ** :** . .. .:: . . . * ", "identical_positions": 94, "similar_positions": 67, "identity": "26.7%" }, { "cls_id": "homologset.agr.MGI:1928948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKE3-1", "uniprot_id": "SCAM5_RAT", "id": "Q9JKE3-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "----------------------------------------------------------------------------------------------------------MAEK-------------VNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFG---TNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSTTPNYTYSNEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKD3-1", "uniprot_id": "SCAM5_MOUSE", "id": "Q9JKD3-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "----------------------------------------------------------------------------------------------------------MAEK-------------VNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFG---TNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAC9-1", "uniprot_id": "SCAM5_HUMAN", "id": "Q8TAC9-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "----------------------------------------------------------------------------------------------------------MAEK-------------VNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFG---TNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0C7-1", "uniprot_id": "SCAM5_DANRE", "id": "Q6P0C7-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "----------------------------------------------------------------------------------------------------------MAE---------------NNFPPLPRFIPLKPCFYQDFN-EIPDQHRTMCKRLYYLWILNSATLAVNLIGCLAWMCGGGGATNFGMAILWLILFTPCSYVCWFRPIYKAFKSDSSFNFMAFFFVFMAQVVISIIQTVGIPGWGVCGWLATITFFS---TNIGSAVVMLIPTIMFTAVAVLSFIALTKVHNFYRGSGGSMSKAQEEWTSGAWKNPHVQQAAQQAAMGAAQGAMQG--QQYSAAPTYNYDDPM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1R1Z1-1", "uniprot_id": "F1R1Z1_DANRE", "id": "F1R1Z1-1", "name": "Secretory carrier-associated membrane protein", "aln": "----------------------------------------------------------------------------------------------------------MAE---------------NNFPPLPGFIPLKPCFHQDFE-EIPDQHRTLCKRFYYLWILYGVTLLVNFFGCMAWMFGGGGVTNFGMSMIWVILFTPCSYVCWFRPIYNAFKTDSSFYFMAFFFVFMAQLFIAIIQAIGIPGWGVCGWLGTISFFG---TSIFASIIMLIPTLMFTAVSVISFLALTKVHNFYRGSGASMSKAQEEWVSGAWKNPHVQQAAQQAALSAATGAMQNPQSPQYSTP--TYDNTM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXV6-1", "uniprot_id": "Q9VXV6_DROME", "id": "Q9VXV6-1", "name": "Secretory carrier-associated membrane protein", "aln": "MSGSGLDENPFGEPNLDNPFADPAIQQARRLQSGAALVSLEDYNPFEEQAKPQLQINSTNTAAVVQPLSQNIPPPQTSSLGASAPSTSIQITSEELQRRQEELDRKAAELDRREQQLQGNVPQLNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLILLFHAGEFETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFNKMGYCGFITAIGQFDGQASGIIVGILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQAEFTTEFLRNQHVQEAASSAVNTAINSQFNN--SRY------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **:**** : :****:***: :** :. .: **:**:*:: ** .*..* : : .* .* ::::: :**:*.******** *:**:.**** **.*** :: * . :*:*::*: * **:: :* *. :.* .:::* :. **.::* ..: :: :*.:**.:*.*::*** *:.: :* ***:**..*. * . :: ", "identical_positions": 82, "similar_positions": 80, "identity": "22.97%" }, { "cls_id": "homologset.agr.MGI:1928953", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKC0-1", "uniprot_id": "CCL24_MOUSE", "id": "Q9JKC0-1", "name": "C-C motif chemokine 24", "aln": "MAGSATIVAGLLLLVACACCIFPIDSVTIPSSCCTSFISKKIPENRVVSYQLANGSICPKAGVIFITKKGHKICTDPKLLWVQRHIQKLDAKKNQPSKGAKAVRTKFAVQRRRGNSTEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PPP2-1", "uniprot_id": "Q5PPP2_RAT", "id": "Q5PPP2-1", "name": "", "aln": "MAGSTTIIASLLLLVACTCCICPTGSVTIPSSCCVTFISKKIPVNRVISYQLANGSICPKAGVIFITKKGHKICTDPKLPWVQKHIKNLDAKRNQPSEGAKALGPKFVIQKLRGNSTKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00175-1", "uniprot_id": "CCL24_HUMAN", "id": "O00175-1", "name": "C-C motif chemokine 24", "aln": "MAGLMTIVTSLLFLGVCAHHIIPTGSVVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKAGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **::.**:* .*: * * .**.***.** *:**:** ***:****:. * * ****** ****:::* *** ***:::::****:::.* *:*: * :*: **.* ", "identical_positions": 61, "similar_positions": 31, "identity": "51.26%" }, { "cls_id": "homologset.agr.MGI:1929004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y708-1", "uniprot_id": "A0A8I5Y708_RAT", "id": "A0A8I5Y708-1", "name": "Serine/threonine-protein kinase 4", "aln": "MEGSAGSSPGRAWCGGWMRGRKEPGRLGQREARCGDADRGRRPGGKRGAGSYLAPAAAAVRARTARRPRRTGHCGSSGCRQRGAVPQSPRLWGPCRAGWQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEVWSDNFMDFVKQCLVKSPEQRATATQLLQHPFVKSAKGAAILRDLINEAMDVKLKRQEAQQR----AVDQDDDENSEEDEMDSGTMVRAAGDDMGTVR-----VASTMSGGANTMIEHGDT-------------------------------------------LPSQLGTMVINTEDEEEEGTMKRRDE-TMQPAKPSFLEYFEQK---------------------EKENQ--------------------------------------INSFGKNVSG-----------------SLKNSSDWKIP----------------------------------QDGDYEFLKSWTVEDLQKRLSALDPMMEQEMEEIRQKYRSKRQPILDAIEAKKRRQQNF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI11-1", "uniprot_id": "STK4_MOUSE", "id": "Q9JI11-1", "name": "Serine/threonine-protein kinase 4", "aln": "--------------------------------------------------------METVQLRNP--PRR-----------------------------QLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQHPFVKSAKGVSILRDLINEAMDVKLKRQEAQQR----EVDQDDEENSEEDEMDSGTMVRAAGDEMGTVR-----VASTMSGGANTMIEHGDT-------------------------------------------LPSQLGTMVINTEDEEEEGTMKRRDE-TMQPAKPSFLEYFEQK---------------------EKENQ--------------------------------------INSFGKNVSG-----------------SLKNSSDWKIP----------------------------------QDGDYEFLKSWTVEDLQKRLLALDPMMEQEMEEIRQKYRSKRQPILDAIEAKKRRQQNF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13043-1", "uniprot_id": "STK4_HUMAN", "id": "Q13043-1", "name": "Serine/threonine-protein kinase 4", "aln": "--------------------------------------------------------METVQLRNP--PRR-----------------------------QLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQR----EVDQDDEENSEEDEMDSGTMVRAVGDEMGTVR-----VASTMTDGANTMIEHDDT-------------------------------------------LPSQLGTMVINAEDEEEEGTMKRRDE-TMQPAKPSFLEYFEQK---------------------EKENQ--------------------------------------INSFGKSVPG-----------------PLKNSSDWKIP----------------------------------QDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T0S6-1", "uniprot_id": "HIPPO_DROME", "id": "Q8T0S6-1", "name": "Serine/threonine-protein kinase hippo", "aln": "--------------------------------------------------MSEPEVTSVVDMKSPNISSS-------------------------CSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRNAKHRSILKPMLEETCAIREQQRANRSFGGVLAASQAKSLATQENGMQQHITDNAFMEDPGTLVPEKFGEYQQSSASDATMIAHAEQGVDEGTLGPGGLRNLSKAAAPAAASSAASPLDMPAVDSGTMVELESNLGTMVINSDSDDSTTAKNNDDQKPRNRYRPQFLEHFDRKNAGDGRGDEKPIATEYSPAAAEQQQQQQQQQQQQQQDEQHLASGANDLNNWEHNMEMQFQQISAINQYGLQQHQQQQQVLMAYPLMNEQLIALNNQPNLLLSNAAPMGQQGIPAAAPAQPPPAYQNQHMHTQSHAYVEGEFEFLKFLTFDDLNQRLCNIDHEMELEIEQLNKKYNAKRQPIVDAMNAKRKRQQNINNNLIKI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :.. . :****.*:** : **:***:: *************:***:..***** *******:***************:**:*******: **** ************:***:************..**:** ***: *********.********:**********************************:****:************:*********.:*********** :***:**:*: ** :* ***.:****.*::*****:**:* *::.** :**: :::*: :: ::: :. ..* .. ::*: *:. .* :: **: . : . *** * : * *:*******::.::. : :. *: . : :*.***:*::* *:::* **.:* . .*:*..: :. :*::**** *.:**::** :* ** *:*::.:**.:*****:**::**::****: ", "identical_positions": 284, "similar_positions": 130, "identity": "38.17%" }, { "cls_id": "homologset.agr.MGI:1929008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAY8-1", "uniprot_id": "A0ABK0LAY8_RAT", "id": "A0ABK0LAY8-1", "name": "Coatomer subunit zeta", "aln": "MRFCGVGGLAESSFRERGRTQRPATQDWVEGQRRGGRARGGAALSVQAASGMQRPEAWPRPHPGEGASAAQAGGAAPPTRA---TEQRFQEPSLYTIKAVFILDNDGRRLLAKYYDD----------TFPSMKEQMVFEKNVFNKTSRTESEIAFLAGMTIVYKSSIDIFLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRTDDSGLTEQSVAQVLQSAKEQIKWSLLK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHH9-1", "uniprot_id": "COPZ2_MOUSE", "id": "Q9JHH9-1", "name": "Coatomer subunit zeta-2", "aln": "---------------------------------------------------MQRPEAWPRPHPGEGASAAQAGGAAPPTRA---TEQR--EPSLYTIKAVFILDNDGRRLLAKYYDD----------TFPSVKEQMVFEKNVFNKTSRTESEIAFLGGMTIVYKSSIDIFLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDETVDGGVILESDPQQVIQKVNFRTDDSGLTEQSVAQVLQSAKEQIKWSLLK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P299-1", "uniprot_id": "COPZ2_HUMAN", "id": "Q9P299-1", "name": "Coatomer subunit zeta-2", "aln": "---------------------------------------------------MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDD----------TFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLTEQSVAQVLQSAKEQIKWSLLK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV89-1", "uniprot_id": "Q9VV89_DROME", "id": "Q9VV89-1", "name": "Coatomer subunit zeta", "aln": "-----------------------------------------------------------------------MDG-----------------FMMDIIKGMCIMDNDGNRILAKYYDKN---------ILSTLKEQKAFEKNLFNKTHRSNTEIIMLDGLTCVYKSNVDLFFYVMGNAYENELILLSVLNCLYDSISLILKKNVEKRLVLENLEIIMLAFDEICDGGIILDADPSSVVKRVDLRNDDIPIAEQTVAQVLQSAREQLKWSILK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53600-1", "uniprot_id": "COPZ_YEAST", "id": "P53600-1", "name": "Coatomer subunit zeta", "aln": "----------------------------------------------------------------------------------------MSSLSLYTVQAVLILDQQGERIYAKYYQPPHRSDEGHQLLFNSVKKQKEFEKQLYRKTHKQDSEILIFEDHLVLYKEYIDITIYLVASLEENEIVLQQGFSAIRGALDLILNSGMDKKNIQENYDMVLLAIDETIDNGVILETDSNTIASRVSKPPTNEPQMALDLDKGFLGAWGFAKSKFQERLQQGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::.: *:*::*.*: ****: : ::*:* ***:::.** : ::** :: . :**. :*: :*::.. ***::* . : .: ::. :*...::*: : ** : :*.:** *.*:**::*.. : .:*. : : : : .* * .: : ", "identical_positions": 40, "similar_positions": 73, "identity": "14.44%" }, { "cls_id": "homologset.agr.MGI:1929022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ESP7-1", "uniprot_id": "F7ESP7_RAT", "id": "F7ESP7-1", "name": "", "aln": "MATPDSPGMDGQTGDTETEVLQSARWQYCGEPDDRQKAVLVQFSNGKLQNPGNMRFTLYNSTDLVNPRQKCHRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAEVFNMQPLFA------------------------------------------------EDSIEHGPPLENQNKTFRDKLDSCI-EAFGSTKQKRSLNSRRMNKVGSESLNFTVAKAAES-IIDTKGVSALVSDAMQDDLQNDSLYLPPCHADATKPEDVYRFEDILSPAEYDALESPSEAFRKVMSEDILKMVEENRSVVTGCWEWPRGVVENKLEFSARAAILYHCSFIIEMLKSLPADEVQRNRQARSIWFLDALLRFRAQKVIKGKSALGP---GIPHIINTKLLKQFTCLTYN-NGSLRN---LISSSMKAKITAYAIILALHINNFQIDLTVLQRDLKLSEKRMIEIARAMRLKISKRKVSLADGR------EEDHRLGTLSVPLPPAQTSDRQSKRKKMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K202-1", "uniprot_id": "RPA49_MOUSE", "id": "Q8K202-1", "name": "DNA-directed RNA polymerase I subunit RPA49", "aln": "MATLESPGMDDQAGDTETEALQSARWLYCGEPDDRQKAVLVQFSNGKLQNPGDMRFTLYNSTDLVNPRQRSHRIVAAETDRLSYVGNNFGTGALKCNALCRHFVGILNKTSGQMEVYDAELFNMQPLFAGMGTEVIKLGGQHLYLLAFCQPSKNLAEAGDLLLSRHRQGHCIAVLLDDDAIEREPPLENQNKTFRDKLDSCI-EAFGSTKQKRSLNSRRMNKVGSESLNLSVAKAAES-IIDTKGVNALVSDAMQDDLQDGVLYLPPCYADAAKPEDVYRFEDILSPAEYDALESPSEAFRKVTSEDILKMIEENS----------------------------HCSYVIEMLKSLPIDEVHRNRQARSIWFLDALIRFRAQKVIKGKRALGP---GIPHIINTKLLKQFTCLTYN-NGRLQN---LISSSMRAKITSYAIILALHINNFQVDLTALQKDLKLSEKRMIEIAKAMRLKISKQKVSLADGR------EESHRLGTLSVPLPPAQNSDRQSKRRKMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZS1-2", "uniprot_id": "RPA49_HUMAN", "id": "Q9GZS1-2", "name": "DNA-directed RNA polymerase I subunit RPA49", "aln": "---------------MAAEVLPSARWQYCGAPDGSQRAVLVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFS------------------------------------------------DVSVESELALESQTKTYREKMDSCI-EAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAET-IIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENS----------------------------HCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGP---GVPHIINTKLLKHFTCLTYN-NGRLRN---LISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGS------EEDHKLGTLSLPLPPAQTSDRLAKRRKIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01080-1", "uniprot_id": "RPA49_YEAST", "id": "Q01080-1", "name": "DNA-directed RNA polymerase I subunit RPA49", "aln": "-----------------MSVKRSVSEIEIESVQDQPSVAVGSFFKG-FRAPSDTTFDLYKKKK----SEKDEFVLHGENERLEYEGYTDSS----SQASNQYVVGLFNPEKKSIQLYKAPVLVSKVVSK------------------------------------------------SSKNLRGPKIKSKSDTRPSALRNALGEAFGTKKAKKAIADLERNRIDSDKLTDSAIDIVDS-VRTAS--KDLPTRAQLDEITSNDRPTPLANIDATDVEQIYPIESIIPKKELQFIRVSS-ILKEADKEKKLELFPYQN----------------------------NSKYVAKKLDSLTQPS--QMTKLQLLYYLSLLLGVYENRRVNNKTKLLERLNSPPEILVDGILSRFTVIKPGQFGRSKDRSYFIDPQNEDKILCYILAIIMHLDNFIVEITPLAHELNLKPSKVVSLFRVLGAIVKGATVAQAEAFGIPKSTAASYKIATMKVPFKLPEMTRRGRGPRR--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VE94-1", "uniprot_id": "Q9VE94_DROME", "id": "Q9VE94-1", "name": "", "aln": "------------------MEDKIIIESVCDHKRDENIPTILKFQNG--SLLGDADFSMVES------------TVDGKKHALVYAGDQVYTGEVKDSEEVDTYIFIRNKLTNKVKVVPVQEALMYNHVY---------------------------------------------------KKLERQKRTGPTMSREHANKKLLKEFGGRKASRFVDNREQMMVNVEVMRQDLDETVNSSMLNEDEEDGTLGDVSINNEEYLASIVPEFNKEATKVDEVYAVESLIPSSLLERLEEEAKVVFSTPVQTLPIKSEYLK-------------------------------SCLAKIQENPVSSKRDFLHIKLIIYMDALQSLISLRSRQMQKAELS---GITEKIENDIRHRFADPNVAKKGTRTN------FSSEKALTHFIVMALLLSEKFEVDINVLSRALATTKARIKQYAHIVNALPK-----------------SNSDILSLRLPSKVPALKSGRRFQRKK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: .* :* .: * : :. : .:.. * * * : . : : * . .::: . .. . . : : ** * .: : . :. : : . .:: : . . :: * :*:. :::* .*.::. : :. : . .. : :.. . : : : ::. * . : : : . .. : : :*: . * : . . : : : : ..* :::. * : * . :: . : : . . : :: :* . . :: ", "identical_positions": 21, "similar_positions": 119, "identity": "4.0%" }, { "cls_id": "homologset.agr.MGI:1929059", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M3Z6-1", "uniprot_id": "A0ABK0M3Z6_RAT", "id": "A0ABK0M3Z6-1", "name": "", "aln": "MTRGARPRPSSVTRRRRRWRGLVSSGDWRRRQRRRRRRRRLELEPSGGGRAGGAGGRGPLRDAADRASPLSGGARSCGAPGASPSMTMGDKKSPTR-PKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVE----------------------------------------------------------------KPDK-------------------------------------------------------------EKPEKDK-------------------------------------DISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CCI5-1", "uniprot_id": "RYBP_MOUSE", "id": "Q8CCI5-1", "name": "RING1 and YY1-binding protein", "aln": "-------------------------------------------------------------------------------------MTMGDKKSPTR-PKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVE----------------------------------------------------------------KPDK-------------------------------------------------------------EKPEKDK-------------------------------------DISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N488-1", "uniprot_id": "RYBP_HUMAN", "id": "Q8N488-1", "name": "RING1 and YY1-binding protein", "aln": "-------------------------------------------------------------------------------------MTMGDKKSPTR-PKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVE----------------------------------------------------------------KQDK-------------------------------------------------------------EKPEKDK-------------------------------------EISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5EG55-1", "uniprot_id": "RYBPB_DANRE", "id": "Q5EG55-1", "name": "RING1 and YY1-binding protein B", "aln": "---------------------------------------------------------------------------------------MGDKKSPTR-PKRQAKPTADNGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKPE----------------------------------------------------------------RPEKDRAEEERPDINPPDEHPVEQR---------------------------------DKDKSEKEQPEKEKKDRE--------------------------------KEIIPAITKKPNSKKNRPKSDIHQSPPSERNSIQSGKSTTKTKNS-HNSRPKLKNIDRSTAQQLAITVGNVTVIITDFKEKTRTSSTSSSTVTSSASSEQQHQSS-GSESMDKGSSRASTPKGDLSLGHDESF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7SYB3-1", "uniprot_id": "RYBPA_DANRE", "id": "Q7SYB3-1", "name": "RING1 and YY1-binding protein A", "aln": "---------------------------------------------------------------------------------------MGDKKSPSR-PKRQAKPSADNGFWDCSVCTFKNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYAAPPPAKKERRERTDRDLPDDDHFDMDNSDSDRLSSLHPDSDHPERLGLEGGQLDRGHSLKERRQERVLDKPQALDTDRRPERAGLTPDLLQQQQPQPQQHPQQPQQPQQHSQQQPQQHPPQQHNRIDREHTDRAMLEKLQPLREHMEKDHPHTAGSGMQPAERMGAEREELKKGKIERAMMEKHKERHKSLTPSKKPTPKKMKPKL-IQKSPAGESNGMKPGKSVTKNNKS-VISRPKLKNVDRSSAQQLAITVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQHLSS-SSESTDKGSSRASTPRRDHSSGHNETL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W215-1", "uniprot_id": "Q9W215_DROME", "id": "Q9W215-1", "name": "", "aln": "---------------------------------------------------------------------------------------MDKKSSPVRRQKRQAKVIEEN-FWDCSVCTYRNSAEAFKCRMCDVRKGTSTRKPRLNSALVAQQAATLPGAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNMPNGK--------------SASGSRHGSGHDRQRHKRYPAR--LKNVDRSTAQTREVTVNSVTVFITEYKAKPVSSRRES--------SEQS-----FSESND---SRS---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..*.** * ***** :: ********::******** :*************:** *****.* .:. : . * . .. : ... : .. :* ***:***:** :**..***:**::* *. :* .* ***. *** * **: ", "identical_positions": 77, "similar_positions": 39, "identity": "16.18%" }, { "cls_id": "homologset.agr.MGI:1929063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61923-1", "uniprot_id": "COPZ1_HUMAN", "id": "P61923-1", "name": "Coatomer subunit zeta-1", "aln": "MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS----------VKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GES6-1", "uniprot_id": "A0A8I6GES6_RAT", "id": "A0A8I6GES6-1", "name": "Coatomer subunit zeta", "aln": "MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS----------VKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61924-1", "uniprot_id": "COPZ1_MOUSE", "id": "P61924-1", "name": "Coatomer subunit zeta-1", "aln": "MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS----------VKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VV89-1", "uniprot_id": "Q9VV89_DROME", "id": "Q9VV89-1", "name": "Coatomer subunit zeta", "aln": "MDGFMMD----IIKGMCIMDNDGNRILAKYYDKNILST---------LKEQKAFEKNLFNKTHRSNTEIIMLDGLTCVYKSNVDLFFYVMGNAYENELILLSVLNCLYDSISLILKKNVEKRLVLENLEIIMLAFDEICDGGIILDADPSSVVKRVDLRNDDIPIAEQTVAQVLQSAREQLKWSILK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53600-1", "uniprot_id": "COPZ_YEAST", "id": "P53600-1", "name": "Coatomer subunit zeta", "aln": "----MSSLSLYTVQAVLILDQQGERIYAKYYQPPHRSDEGHQLLFNSVKKQKEFEKQLYRKTHKQDSEILIFEDHLVLYKEYIDITIYLVASLEENEIVLQQGFSAIRGALDLILNSGMDKKNIQENYDMVLLAIDETIDNGVILETDSNTIASRVSKPPTNEPQMALDLDKGFLGAWGFAKSKFQERLQQGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::.: *:*::*:*: ****: * :*:** ***:::.***: ::** :::. :**. :*: :*::.. ***::* :..: .::. :*...::*: : ** : ::**.** *.*:**::*.. :. ** : * : : : .* * .: . ", "identical_positions": 46, "similar_positions": 72, "identity": "23.83%" }, { "cls_id": "homologset.agr.MGI:1929064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1Q1N4-1", "uniprot_id": "A0A8M1Q1N4_DANRE", "id": "A0A8M1Q1N4-1", "name": "Carbohydrate sulfotransferase", "aln": "------------MQKLHRHCLLLGAVFITMSFIVVFWDEVRVGPPYPRTNHRASS--------------------------------------------------------------------------------KHLAQFKLRQAHRKHLIKELCSANSSLNYRQKSITLD--------HLIVDDHHRVIYCYVPKVACSNWKRVMFVLSQNLKAPDGAPYLDPLDIPLEIIHNSTVHNTFKKLWMRHGRYARPLMHQKLKNYTKFLFVRDPFVRLISAYRDKFAEPNEYYYYKFGFMILQRYANISQPPTLAPEAFRAGIRPSFSHFIKFLLDPQTEKEKP--FDEHWKQIHRLCHPCQIDYDFIGKLETLDEDTEHLLKILGLDKHIHFPPGYENRTAVDWEQEWFANISLADRRELYSLYETDFKLFGYDKPETLLNE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RER3-1", "uniprot_id": "A0A8M1RER3_DANRE", "id": "A0A8M1RER3-1", "name": "Carbohydrate sulfotransferase", "aln": "------------MQKLHRHCLLLGAVFITMSFIVVFRDEVRVWPPYLRTNHRASS--------------------------------------------------------------------------------KHLAQFKLRQAHRKHLINELCSANSSLNYRQKSFTFDQIPDSSLNHLIVDDHHRVIYCYVPKVACSNWKRVMFALSQNLKAPDGAPYLDPHDMPLKIIHNSTVHNTFKKLWMRHGRYARPLMHQKLKNYTKFLFVRDPFVRLISAYRDKIAEPNEYYYYKFGSMILQRYANISQPPTLAPEAFRAGIRPSFNHFIKYLLDPQTEKEKP--FDEHWQQIHRLCHPCQIDYDFIGKLETLDEDTEHLLKILGLDKHIHFPPGYENRTAVDWEQEWFANISLADRRELYSLYETDFKLFGYDKPETLLNE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PZ65-1", "uniprot_id": "A0A8M1PZ65_DANRE", "id": "A0A8M1PZ65-1", "name": "Carbohydrate sulfotransferase", "aln": "------------MQKLHHFCFLLGAVFITLFFIVVFWDEVRVG----TYQHMDSS--------------------------------------------------------------------------------KNLKQ---RQAHRKHLINKLCLANSSLLFRDKLITFDQIPNKALDHLIVDDRHRVIYCFVPKVACTNWKRVMIVLSQNLKAPDGAPYLHPLDIPIEVIHNSTVHKTFNNLWIHHGRYARPLMHQKLKNYTKFLFVRDPFVRLISAFRAKFNRPDEYFYSNYGSTMLQRYANISHPPASAQEAFSAGIRLSFTHFIQYLLDPQTEKEKP--FNEHWQQIHRLCHPCQIDYDFIGKLETLDEDTEHLLKILGLDKHIHFPPGNENRTAVDWEREWFANISVAHRRKLYSLYETDFKLFGYDKPETLLNE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q498S0-1", "uniprot_id": "Q498S0_RAT", "id": "Q498S0-1", "name": "Carbohydrate sulfotransferase", "aln": "----------MTKPRLFRLWLALGSALMIL-LIIVYWDNVGTAHFYLHTSLSRPH--ILEPLPTQG------LAEENVLASDVDEFLDTLLSSDAKHNDLSRRKTEQPPVLTPSKPVLSHMEENVRGYDWSTHDAQQNPDRDRQQAERRSLLRDFCAN-ASLAFPTKDRSFDDIPNYELNHLIVDDRHGVIYCYVPKVACTNWKRVMIVLSESLLD-RGSPYRDPLDIPREHVHNTSTHLTFNKFWRRYGKFSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASVSEAFSAGLKVSFANFIQYLLDPHTEKLAP--FNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLRSLKVDSQLHFPPSYRNRTASSWEEDWFANIPLAWRQQLYKLYEADFVLFGYPKPENLLRD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LL3-1", "uniprot_id": "CHSTC_MOUSE", "id": "Q99LL3-1", "name": "Carbohydrate sulfotransferase 12", "aln": "----------MTKPRLFRLWLVLGSALMIL-LIIVYWDNVGTAHFYLHTSLSRPH--ILEPLPTQG------LVEENVFTSDVDEFLDTLLSSDAKHNDLSRRKTEQPPVPAPSKPVLSHMEENVRGYDWSTHDAHQNPDRDRQQAERRSLLRDFCAN-ASLAFPTKDRSFDDIPNYELNHLIVDDRHGVIYCYVPKVACTNWKRVMIVLSESLLD-RGSPYRDPLDIPREHVHNTSTHLTFNKFWRRYGKFSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASVSEAFSAGLKVSFANFIQYLLDPHTEKLAP--FNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLRFLKVDSQLHFPPSYRNRTASSWEEDWFANIPLAWRQQLYKLYEADFVLFGYPKPENLLRD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRB3-1", "uniprot_id": "CHSTC_HUMAN", "id": "Q9NRB3-1", "name": "Carbohydrate sulfotransferase 12", "aln": "----------MTKARLFRLWLVLGSVFMIL-LIIVYWDSAGAAHFYLHTSFSRPH--TGPPLPTPGPD----RDRELTADSDVDEFLDKFLSAGVKQSDLPRKETEQPPAPG-------SMEESVRGYDWSPRDARRSPDQGRQQAERRSVLRGFCAN-SSLAFPTKERAFDDIPNSELSHLIVDDRHGAIYCYVPKVACTNWKRVMIVLSGSLLH-RGAPYRDPLRIPREHVHNASAHLTFNKFWRRYGKLSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASAREAFRAGLKVSFANFIQYLLDPHTEKLAP--FNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLQLLQVDRQLRFPPSYRNRTASSWEEDWFAKIPLAWRQQLYKLYEADFVLFGYPKPENLLRD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QL27-1", "uniprot_id": "A0A2R8QL27_DANRE", "id": "A0A2R8QL27-1", "name": "Carbohydrate sulfotransferase", "aln": "MALSQSKSTKMGKSRLFRIFMIVGAVFMIL-LIIIYWDDVGASNFYLHTTISGPHPSRLSPQGRRGPEKKVEEDKESSFLTDIDAFVNQFLEGTADPTEQVRG--EPPPGDPHNQSSEKSDEKFVPRREWKIHLSPIDPEKKQKQENRKQLIQDVCGNKSVFDFPGKNRTFDDIPNKELDHLIVDDRHGIIYCYVPKVACTNWKRIMIVLSESLLV-DGVPYQDPLDVPQELIHNSSLHFTFNKFWKRYGKFSRHLMKIKLKKYTKFLFVRDPFVRLISAYRNKFEQENEDFYKRFALVMLKKYSNYTDPPASVVDAFAAGIRPSFSNFVQYLLDPSTEKEMP--FNEHWRQMYRLCHPCQINYDFVGKLETLDEDAEHLLRILRVDNIVEFPESHRNRTVSSWEQDWFANIPLETRKELYRLYEADFKLFGYSKPEKLLHE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJG5-1", "uniprot_id": "Q9VJG5_DROME", "id": "Q9VJG5-1", "name": "Carbohydrate sulfotransferase", "aln": "----------MDQLVWLSFCISIGFSLLGNFSTGLPFEDGNNNNVK-------------------------------------------------------------------------------------------ITRRSLELTQTINIQRQEFMQRQCELLGDHTQTLEDLSELQMDHMIVDKEHKLLYCYVPKVACTNWKRVLMMLTNKWHN-----GTDPLQIPGSLAHSVGMFTKLYDLSEAE------QQQVLSDEYTRFILVRHPLERLLSAYRNKLEGDSP--SARYFQSRVGRQIVKELRPGASNNSLERGDDVSFGEFIQYLVTPELSRANQSDYNEHWEVIAKLCNPCVMKYNVVGKYDTLLDDSALALYLAGADN-LTFPTGHKPSSTRANLRNYFDPLPIGAIRKLYDIYEDDFRLFDYALDEVLGFEFG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :: : :. . . : . : ::: *:***..* :**:******:****::: *: . .* :* . *. . .: .: : .:**:*::**.*: **:**:* *: . .: : * ::: * ** .*:::*: * .: ::***. : :**:** :.*:.:** :** :*: * * : ** . . :. .::* :.: ::** :** ** **.* * * : ", "identical_positions": 70, "similar_positions": 90, "identity": "15.77%" }, { "cls_id": "homologset.agr.MGI:1929069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLN8-1", "uniprot_id": "RNF8_RAT", "id": "Q4KLN8-1", "name": "E3 ubiquitin-protein ligase RNF8", "aln": "MGEPDPLVSG-----QLAARRSWCLRRLGMDREWLQLEAGSEVTIGRGFSVTYQLISKVCPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRERLAPLQGYCIRKGDHIQLGVPLESKEHAEYEYEVIEEDRESLAPCLAPKNDHTTEKHKGLRTKRKFSSDGVESLPAEGPSDLRCPLAKGSSKPAEPEKLHGKGEAASQPLGCLCPTLASLEASERTAGPHACSTLPKVLEL-YPKKQKACSPSASQSSLELFKMTMSRMLKLKTQMQEKQIAVLNVKRQARKGSSKKVVRMEKELRDLQSQLYAEQAQQQARVEQLEKTFQEEEQHLQGLEKEQGECDLKQQLLQALQEHRALMEELDRSKKDFEKIIQAKNKELERTKEEKDKVQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSFCISEWMKRKVECPICRKDIESRTNSLVLDNCISKMVERLSSDVKERRSVLIRERRAKRLL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC56-1", "uniprot_id": "RNF8_MOUSE", "id": "Q8VC56-1", "name": "E3 ubiquitin-protein ligase RNF8", "aln": "MGEPDPLVSG-----QLAARRSWCLRRLGMDCEWLQLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRERLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGSRTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSLKASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQIAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGLEKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKEEVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESRTNSLVLDNCISKMVDNLSSDVKERRSVLIRERRAKRLS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76064-1", "uniprot_id": "RNF8_HUMAN", "id": "O76064-1", "name": "E3 ubiquitin-protein ligase RNF8", "aln": "MGEPGFFVTG-----DRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSK-TTGAPIYPGFPKVTEV--HHEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803C1-1", "uniprot_id": "RNF8_DANRE", "id": "Q803C1-1", "name": "E3 ubiquitin-protein ligase rnf8", "aln": "MEKTEEPPSSNNEEDSPAKEKIWCLQRVGRDSDWLRLFEDSEVSVGRGLNVTHQILSSSCPLMISRIHCVFKLNEGRQWTVTDNKSLNGVWVNGKRIPPSTPCILHQSDSVRLGVPLDGNP-VEFDYILVQKNFDDVKSFLSG-NLGKDSGAASLSQKLKNSKRKFDGGDESEPCPTQHSKSK-LYRSSAPDKSRAQPCPSGERRETLKLSSRPLEEDRDKAGSSSS---------------TCSDSSQHLATLHRYNRSLM-VLKGRVGDTQKRAAELEQQQTQTPEREKEMQDLQTQLEALRGQLRSQQEQALRRMETLEKSFCEEERRLETEKAQQNEVGLKKQLEEALKEHRKVIEELKHAWQGFKEVLQAKDKELEVTKEEKEKAKAQKEEVVTQMTEVLESELQCSICSELFIEAVTLNCAHSFCQHCISEWRNRKDKCPMCWQNITSQTRSLVLDNCIDRMVENLSADMRERRLVLINERKGERSKSESISSSGGNK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. :. . * : ***:*:* . ** * . **::***:.**:*::*. ******* ***:* * ***: *********:* *: * :::.* ::*****:.. .*::* : ::: : : . *: * . * * * . . . .. : : .. * * :.: :. * .*: .. :*. ... .* :*. :: :: :*: : :*: * :: :: .*:: :: :*. *:.** ::* * *:* ***:* ** : *: : *.* .**:** :**:** ::***. : :.*: ::***:**** *****:* :******:::*.::**.**** **** **************..**.** :** :**:* ::* *:* ********.:**:.**::::*** ***.**:.:* ", "identical_positions": 176, "similar_positions": 143, "identity": "34.92%" }, { "cls_id": "homologset.agr.MGI:1929074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRU9-1", "uniprot_id": "D3ZRU9_RAT", "id": "D3ZRU9-1", "name": "Translesion synthesis protein REV1", "aln": "---MVAWGG----AEGPLRSSTMRRGGWRKRA-EEDGWEKWGGYMAAKVQKLEEQFRSDAAKQ--KDGTASAIFSGVAIYVNGYTDPSAEELRNLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKAGRLLSSVPYQLYTKPSTAQKSLNFTPVCKPEEPVPGPSE-----------------IAKQLTNRVNHIIKKIETENEVKANGVSSWNEDSADDGFSSEGLGQTFPGRKQNGVMHPRDT--AVIFNGHAHSSNGALKTQDCLVPVDHSVASRLSLDSTQEEKR--AEKSSTDFRDCSR-QHLQHSTTNADTLCSP---------HRTSSLSPS-LHSNTKINGAHHSTVQGPSSTKSTS-ALTLSKVAPSVPSKPSDCSFISDFYSRSRLHHISTWKCELTEFVSALQ--RQRSG--VFPGREKLKKVKTGRSSLVVTDTGDMSVLSSPRPQSCVMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRG---TGRAPLRPGANPQLEWQYYQNK---LLKGKAADIPDSSVWENQDSAQTNGIDS---VLSKAEIASCSYEARQVGIKNGMFFGHAKQLCPN---LQAVPYDFHACREVAQALYETLASYTHS--IEAVSCDEALID--VTDILAETKLSPEEFAAALRMEIKNKT-QCAASVGIGSNILLARMATKKAKPDGQYHLQP-DEVDDFIRGQLVTSLPGVGRSMESKLAS--LGIKTCGDLQC-LTMAKLQKEFGPKTGQMLYRFCRGLDDRP-------VRTEKERKSVSAEINYGIRFTQPREAEAFLLSLSGEIQSRLEAAGMKGKRLTLKIMVRKPGAPIETAKFGGHGICDNIARTVTLDQATDSAKIIGKATLNMFHTMKLNISDMRGVGIQVHQLVPANLHPSTCSSRPSAQSSLFSGLPHSVRDLFQLQKAKKPTEEEHNEG-LAAVDLEVSSNSRACGLLSPPSAHLAT-VSPDANRGECSRKWNGLHSPIGGQSRLNLSIEVPSPSQIDQSVLEALPPDIREQVEQAYAAQQGEPRGSKKKEPVNGCSSGVLPHPVGTVLLQIP-EPQEPNNSDTRISVIALPAFSQVDPDVFAALPAELQKELKAAYDQRQRQGEDTTQQQPASTSVPKNPLLQLKPPAMKDKRNKRKNPIGSPRK-------------IQSLPG---TSGSPQKLMDGFLQHE----ERPLEEVSASTPGAQSLSGLQCGSQSSCFRPAAPNLAGAVEFSDVKTLLKEWITTIS---DPMEEDILQVVKYCTDLIEEKDLEKLDLVIKYMKRLMQQ--SVESVWN--MAFDFILDNVQVVLQQTYGSTLKVT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920Q2-1", "uniprot_id": "REV1_MOUSE", "id": "Q920Q2-1", "name": "Translesion synthesis protein REV1", "aln": "----------------------MRRGGWRKRT-ENDGWEKWGGYMAAKVQKLEEQFRTDAANQ--KDGTASAIFSGVAIYVNGYTDPSAEELRNLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKAGRLLSSAPYQLYTKPSAAQKSLNFNPVCKPEDPGPGPSN-----------------RAKQLNNRVNHIIKKIETESEVKANGLSSWNEDGVNDDFSFEDLEHTFPGRKQNGVMHPRDT--AVIFNGHTHSSNGALKTQDCLVPVGNSVASRLSLDSTQEEKR--AEKSNADFRDCTV-QHLQHSTRSADALRSP---------HRTNSLSPS-LHSNTKINGAHHSTVQGPSSTKSTS-VLTLSKVAPSVPSKPSDCNFISDFYSRSRLHHISTWKCELTEFVNTLQ--RQSSG--IFPGREKLKKVKTGRSSLVVTDTGTMSVLSSPRHQSCVMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRG---TGTAPLRPGANPQLEWQYYQNR---ALRGKAADIPDSSVWENQDSTQTNGIDS---VLSKAEIASCSYEARQVGIKNGMFFGYAKQLCPN---LQAVPYDFHACREVAQAMYETLASYTHS--IEAVSCDEALID--VTDILAETKLSPEEFAAALRIEIKDKT-KCAASVGIGSNILLARMATKKAKPDGQYHLQP-DEVDDFIRGQLVTNLPGVGRSMESKLAS--LGIKTCGDLQC-LTMAKLQKEFGPKTGQMLYRFCRGLDDRP-------VRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLEAAGMKGKRLTLKIMVRKPGAPIETAKFGGHGICDNIARTVTLDQATDSAKIIGKATLNMFHTMKLNISDMRGVGIQVNQLVPANSNLSTCSSRPSAQSSLFSGRPHSVRDLFQLQKAKKPTEEEHKEVFLAAVDLEVSSTSRACGLLSPLSAHLAASVSPDTNSGECSRKWNGLHSPVSGQSRLNLSIEVPSPSQIDQSVLEALPLDLREQIEQVCAAQQGEPRG-KKKEPVNGCSSGVLPHPVGTVLLQIP-EPQEPCNSDSKISVIALPAFSQVDPDVFAALPAELQKELKAAYDQRQRQGEDTTHQQPTSTSVPKNPLLQLKPPAMKDKRNKRKNLIGSPRKSP--LKNKLLSSPAKTLPG---AYGSPQKLMDGFLQHEGMASERPLEEVSASTPGAQDLSSLLPG-QSSCFRPAAPNLAGAVEFSDVKTLLKEWITTIS---DPMEEDILQVVRYCTDLIEEKDLEKLDLVIKYMKRLMQQ--SVESVWN--MAFDFILDNVQVVLQQTYGSTLKVT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBZ9-1", "uniprot_id": "REV1_HUMAN", "id": "Q9UBZ9-1", "name": "Translesion synthesis protein REV1", "aln": "----------------------MRRGGWRKRA-ENDGWETWGGYMAAKVQKLEEQFRSDAAMQ--KDGTSSTIFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKAGRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSN-----------------IAKQLNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGS--TAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDK--AEKSSTDFRDCTL-QQLQQSTRNTDALRNP---------HRTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQ--RQSNG--IFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRG---TGRAPLRPGANPQLEWQYYQNK---ILKGKAADIPDSSLWENPDSAQANGIDS---VLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPN---LQAVPYDFHAYKEVAQTLYETLASYTHN--IEAVSCDEALVD--ITEILAETKLTPDEFANAVRMEIKDQT-KCAASVGIGSNILLARMATRKAKPDGQYHLKP-EEVDDFIRGQLVTNLPGVGHSMESKLAS--LGIKTCGDLQY-MTMAKLQKEFGPKTGQMLYRFCRGLDDRP-------VRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT--SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIP-EPQE-SNSDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPG---ACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSD-PAGCVRPPAPNLAGAVEFNDVKTLLREWITTIS---DPMEEDILQVVKYCTDLIEEKDLEKLDLVIKYMKRLMQQ--SVESVWN--MAFDFILDNVQVVLQQTYGSTLKVT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GEY2-1", "uniprot_id": "A0AC58GEY2_DANRE", "id": "A0AC58GEY2-1", "name": "Translesion synthesis protein REV1", "aln": "MTRLAEGGGKPTPQLGQARSLSMSRDGWRKKASENDGWGGQGGYMAAKVSKLEEQFQKDAPREQKKDGKSSCIFSGVAIYVNGYTDPSAAELRRLMMLHGGQFHLYYSRSKTTHIIATNLPNFKIQELKGEKVVRPEWIIDSIKAGRQLSYIQYQLYAK----QKGLNFTRVSGIEGQDPSSNHGPDIKPQPSHTLSKDVLKSTQANHMANYTEKTDHQLDIRLRNGLHSIISEVDAEKSRVNGIHDDDDDDDIACSILPRGSQDTLLTNGHVHPVNGALKPQDFADHHPHVVDKASNQSHLPQDKYREGEEPCCSYTESKANSHLRSLISAASPAKQPGPHNMQTDLHQKPTSNSGTLGAPQKASLHDQTTVRLNGSYHVTSNSSTLANSSNQSGKSSAEAGIISEFFSHSRLHHISTWRNEFSEYVNSLQSRRRAAGGAVFSGREKLKKLKAN------CNSGSLMAAPQVR-QSCVLHVDMDCFFVSVGIRHRPDLIGKPVAVTSNRG---PGRVAQRPGANPQLEFQYYQNKQKHYRKEKTDGDLEMTPSPQDGEVPSNGVHEDLAALSMAEIASCSYEARQAGVRNGMFFGRAKQLCPD---LQSVPYDFHAYKEVALAMYEILASYTHN--IEALSCDEALVD--ATALLVELGVSPDELARSIREDIKEKT-GCCASVGMSSNILLARMATRKAKPKGQYLLRS-EEVDDFIRDQPVSSLPGVGRSMSSKLTS--LGVSTCGDLQQ-LSLSQLQREFGPRTGQTLFRFCRGLDDRP-------VRSEKERKSVSAEMNYNIRFTQVEEAESFLNNLSMEVQKRLEGAGLRGRRVTLKVMMRKPGAPVEPAKYGGHGICDNFARSVLLAQPTDSGRVIASEAIKLFHAMKLNVKDMRGVGLQVQQLDGSHADPSGQGPSRGRSIRDLLLAKQSAHSPSKESPSQDGLISASSSRAFSSNQKRVTPALSPPPSTSSSSSPPPSFTIIDPMPGTSKGDYHHPHTPNHVRACLNISIEVPSPSQVDPSVLKALPIDIRRQVEETWRYREEQPSTSSHYSTPPRPPS--TPPPGPSLVLQLPNQPGQPCTTG---IILELPDFSQVDPDVFAALPRELQEELCSAYRNK-----GNAQAQASTVVEQKNSFPQLKQPAVGKLKRRYKKRNTSPAKNG-------SSPLKKMFPGNSPAKTSPSKTLP-----------LPLREQDLKCP--SSLSTDVPETLPKPIPRPAPTLAGAHEFSEIRTLLREWVTTIS---EPMEEDILQVVKYCTELVEDKDLEKLYLVIKYMKRLMQQ--SSESVWS--MAFDFVLDNVQVVVQQTYGSTLKIT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0P2-1", "uniprot_id": "REV1_DROME", "id": "Q9W0P2-1", "name": "DNA repair protein Rev1", "aln": "----------------------MTRD-------EDNGFSEWGGYFEAKKSKLEEQFAAASDPFR-----KSDLFQGISIFVNGRTDPSADELKRIMMVHGGTFHHYER-SHTTYIIASVLPDVKVRNMNLSKFISAKWVVDCLEKKKIVDYKPYLLYTNQKTSQPMLIFG---------------------------------KPKDNGANESKSDVEPPKDKAEVEVDSTKDETQMELG----------GILKN--------------------------------------------------------------------------------------------------LQQAVATSPEKEASASESKITNLSTTSNNS----------TTARTAADPNFLSEFYKNSRLHHIATLGAGFKQYVCRLRQKHGTQG---FPKRETLKSLANS---------------HHNCLERYVMHIDMDCFFVSVGLRTRPELRGLPIAVTHSKGGNAATDVPVHPQADRKAELELFAQR-----------FEHHFHDGDKAEKVRSGFDK---KMSLSEIASCSYEAREKGIRNGMFVGQALKLCPE---LKTIPYDFEGYKEVAFTLYDTVAQYTLN--IEAVSCDEMFVE--LTDLAHELNVDVMAFVSHLRQEVYSKT-GCPCSAGVAGNKLLARMATKEAKPNGQFLLDSSNDILAYMAPMSLDLLPGVGSSISHKLKQ--AGLNNCGDVQN-TTLEKMEKVLGKKLGQNLFQNCRGIDDRP-------LAYEQIRKTVSAEMNFGIRFTNSVECEQFLCQLSEEVTKRLVEIRRKARSINLKIMVRAAEAPVETSKYMGHGVCDIINKSSLIKYATDDVNVITTVVLDLMKDADIPPDELRGLGIHLTRLEDAN------EVRKENNIKEMFGKMSEMRKDKPIPQGAVGDKSIGDDKVNKPLVFENKPKPREPRNVLSMLTAAAVSRKSVTEDRSQRGTSKPITRPLSLVP------------KLDEDVLAQLPEDIRLEVIANREEHLCIAEYDGYRSP------------------QYPTLRSPP----------LLNPYVTTNVSPLKATDLKPSTSRAAVARLQKRKERKEQEHYIRSDQIVADYIDDLPDFVNPHILKLISHPVEMP---------ELLMG------------------------------------------------------------------------DNYKDLLNDWVSREE---VPKPNDVDLILKQVSRMIKNDQLDHVCDVMKYWCRIINMKRSSSCCWH--VAYKHIEESIQNQMLTIEGYSLLFIEYIRCIKCS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12689-1", "uniprot_id": "REV1_YEAST", "id": "P12689-1", "name": "Translesion synthesis protein REV1", "aln": "-------------------------------------MGEHGGLVDLLDSDLEYSINRETPDK------NNCLSQQSVNDSHLTAKTGGLNARSFLSTLSDDSLIEYVNQLSQTNKNNSNPTAGTLRFTTKNISCDELHADLGGGEDSPIARSVIEIQESDSNGDDVKKNTVYTR---------------------------EAYFHEKAHGQTLQDQILKDQYKDQISSQSSKIFKNCVIYINGYTKPGRLQLHEMIVLHGGKFLHYLSSKKTVTHIVASNLPLKKRIEFANYKVVSPDWIVDSVKEARLLPWQNYSLTSKLDEQQKKLDNCKTVNSIP------------LPSETSLHKGSKCVGSALLPVEQQSPVNLNN-------LEAKRIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNEN-------------IHKYTKITDK-------------------DTYIIFHIDFDCFFATVAYLCRSSS-------------------------------------------------FSACDFKRDPIVVCHGTKN-------SDIASCNYVARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRLNIFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCTVSIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHSTLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEESLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNEINKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGIIATEMKSLYRTLGCPPMELRGLALQFNKLVDVG---------PDNNQLKLRLPFKTIVTNRAFEALPEDVKNDINNEFEKRNYKRKESGLTSNSLSSKKKGFAISRLEVNDLPS-----------------------------TMEEQFMNELPTQIRAEVRHDLR------------------------------------------------------------------IQKKIQQTKLGNLQEKIKRREESLQNEKNHFMGQNSIFQPIKFQNLTR-------------------------------------------------------------------------------------------------FKKICQLVKQWVAETLGDGGPHEKDVKLFVKYLIKLCDSNRVHLVLHLSNLISRELNLCAFLNQDHSGFQTWERILLNDIIPLLNRNKHTYQTVRKLDMDFEV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . ..** .: : . : . : :.... : : :: .. . : . * .:. .:. : : : : . .: . . : * .. : . * : .. .. : .:::.:: .*****:: :.: . . .. ..: ::*:*:****.:*. *.. * .. ::****.* **. *::***:.. * :: *: * ::** *. : : ::*. : . * .:* ** . . : : :* :: . * * * * ... :***:* : ***.* : : : ***** * :* . . . .*:: :: :: .* : * :. :* **. **::* ::*:.***.: : : *: . : :* :.**:* * **:*..*: * * ** : :: : .*:. :* . .: : ::**:.::. :* . : . .. . . :: ..: ** ::* :: : . . : . . : : .. *:.:*:: * :*: .:: : ... :. : : : * :: . ::. : . : : ", "identical_positions": 103, "similar_positions": 236, "identity": "7.56%" }, { "cls_id": "homologset.agr.MGI:1929076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R118-1", "uniprot_id": "HTRA1_MOUSE", "id": "Q9R118-1", "name": "Serine protease HTRA1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSLRTTLLSLLLLLLAAPSLALPSGTGRSAPAATVCPEHCDPTRCAPPPTDCEGGRVRDACGCCEVCGALEGAACG----LQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCGS-----------------------------------------------------------DAKTYTNLCQLRAASRRSEKLRQPPVIVLQRGACGQGQED-PNSLRHKYN-------FIADVVEKIAPAVVHIELYRK-----------------LPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNK--NRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSE--LRPGEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAVTK----KKYIGIRMMSLTSSKAKELKDRHRDFP-DVLSGAYIIEVIPDTPAEAG--GLKENDVIISINGQSVVTANDVSDVIK-----KEN-TLNMVVRRGNEDIVITVIPEEIDP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZK5-1", "uniprot_id": "HTRA1_RAT", "id": "Q9QZK5-1", "name": "Serine protease HTRA1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQFLRTALLSLLLLLLAAPSLALPSGISRSAPAATVCPEHCDPTRCAPPPTDCEGGRVRDACGCCEVCGALEGAVCG----LQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCGS-----------------------------------------------------------DAKTYTNLCQLRAASRRSEKLRQPPVIVLQRGACGQGQED-PNSLRHKYN-------FIADVVEKIAPAVVHIELYRK-----------------LPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNK--NRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSE--LRPGEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKTVTK----KKYIGIRMMSLTSSKAKELKDRHRDFP-DVISGAYIIEVIPDTPAEAG--GLKENDVIISINGQSVVTANDVSDVIK-----KEN-TLNMVVRRGNEDIVITVVPEEIDP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92743-1", "uniprot_id": "HTRA1_HUMAN", "id": "Q92743-1", "name": "Serine protease HTRA1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQIPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARDACGCCEVCGAPEGAACG----LQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCGS-----------------------------------------------------------DANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQED-PNSLRHKYN-------FIADVVEKIAPAVVHIELFRK-----------------LPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNK--HRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSE--LRPGEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITK----KKYIGIRMMSLTSSKAKELKDRHRDFP-DVISGAYIIEVIPDTPAEAG--GLKENDVIISINGQSVVSANDVSDVIK-----RES-TLNMVVRRGNEDIMITVIPEEIDP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GMI0-1", "uniprot_id": "HTR1A_DANRE", "id": "Q6GMI0-1", "name": "Serine protease HTRA1A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MILVTLFCICALVTSLQADARLSKR----YVIGGCPSHCDKSMCPTMPKDCSTGQVMDHCNCCLVCASGEGEACGGVGKLGDPVCGESLECSVTGGVSYSATVRRRGKQGVCVCKSSDPVCGS-----------------------------------------------------------DGVSYRDICELKRVSNRAQSLQQPPVLFIQRGACGTSLHDNPNSLRYKYN-------FIADVVEKIAPAVVHIELYRK-----------------MVYSKREMAVASGSGFVVSDDGLIVTNAHVVANK--NRVKVELKNGASYDAKIKDVDEKADIALIKIDLPNKLPVLLLGRSAD--LRPGEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESYDRLARGRGTTK----KRYIGVRMMTLTPSLSKELKGRLRDFP-DITSGAYVIEVISKTPAAAG--GLKEHDVIISINGQRISTATDVSAIIK-----KES-SLRVVVRRGNEDIILTIIPMEIDP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A9JRB3-1", "uniprot_id": "HTR1B_DANRE", "id": "A9JRB3-1", "name": "Serine protease HTRA1B", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLLILCASIILVPLLCDARIIKR----YVIG-CPERCDKSLCPPIPPDCLAGDILDQCDCCPVCAAGEGESCGGTGKLGDPECGEGLECAVSDGVGATTTVRRRGKTGVCVCKSSEPVCGS-----------------------------------------------------------DGVSYRNICELKRVSNRAQKLQQPPIIFIQRGACGKGHEENPDSLRHRYN-------FIADVVEKIAPAVVHIELFRK-----------------NVFN-REVAVASGSGFVVSEDGLIVTNAHVVANK--HRVKVELKTGTTYDAKIKDVDEKADIALIKIDAPMKLPVLLLGRSAD--LRPGEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESHDRQAKGKTATK----KKYIGVRMMTLTPTLAKELKQRKNDFP-DVTSGAYVIEVIPKTPAEVG--GLKESDVIISINGQRITSASDVSTAIK-----TDE-SLRAVVRRGNEDIILTIIPEEIDP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFJ3-1", "uniprot_id": "HTRA2_DROME", "id": "Q9VFJ3-1", "name": "Serine protease HTRA2, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRGSHRLEVIFKR------------------CIASPVLHSHAANRRSS----QLAIKEGDPNS------NGNSGQYQQNGEQKEKGWRRLVR------FFVPFSLGAVVSA-----------------------------------------------------------AIIQREDLTPTIAASKMT-----------GR--------------RRDFN-------FIADVVAGCADSVVYIEIKDTRHF--------------DYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVN-NLSVMRLGKSST--LRSGEWVVALGSP----LALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAHSG--GLQPGDIVTHINKKEIKNSSDVYDALA-----DNSKTLDIVILRGVKQMHVTITPEDP-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53920-1", "uniprot_id": "NM111_YEAST", "id": "P53920-1", "name": "Pro-apoptotic serine protease NMA111", "aln": "MTISLSNIKKRDHSKISDGTSGESSLVKRKQLESATGDQEEEYTDHEIIIEPLHFANNNNTVLTDSENYLRWQNTISNVVKSVVSIHFSQVAPFDCDSALVSEATGFVVDAKLGIILTNRHVVGPGPFVGYVVFDNHEECDVIPIYRDPVHDFGFLKFDPKNIKYSKIKALTLKPSLAKVGSEIRVVGNDAGEKLSILAGFISRIDRNAPEYGELTYNDFNTEYIQAAASASGGSSGSPVVNIDGYAVALQAGGSTEASTDFFLPLDRILRALICIQTNKPITRGTIQVQWLLKPYDECRRLGLTSERESEARAKFPENIGLLVAETVLREGPGYDKIKEGDTLISINGETISSFMQVDKIQDENVGKEIQLVIQRGGVECTVTCTVGDLHAITPHRYVEVCGATFHELSYQMARFYALPVRGVFLSSASGSFNFDSKERVGWIVDSIDNKETPDLDTFIEIMKTIPDRKRVTVRYHHLTDQHSPLVTSIYIDRHWCNEFRVYTRNDTTGIWDYKNVADPLPADALKPRSAKIIPIPVNNEKVAKLSSSLCTVATMAAVPLDSLSADILKTSGLIIDAEKGYVLVSRRVVPHDCLDTFVTIADSLVVPATVEFLHPTHNFAIVKYDPELVKAPLITPKLSTTRMKRGDKLQFIGFTQNDRIVTSETTVTDISSVSIPSNLIPRYRATNLEAISIDCNVSTRCNSGILTDNDGTVRGLWLPFLGERLENKEKVYLMGLDIMDCREVIDILKNGGKPRVSIVDAGFGSISVLQARIRGVPEEWIMRMEHESNNRLQFITVSRVSYTEDKIHLETGDVILSVNGKLVTEMNDLNGVVSSADGILPSAMLDFKVVRDGNIVDLKIKTVEVQETDRFVIFAGSILQKPHHAVLQAMVDVPKGVYCTFRGESSPALQYGISATNFITHVNEIETPDLDTFLKVVKTIPDNSYCKMRLMTFDNVPFAISLKTNYHYFPTAELKRDNITHKWIEKEFTGNSQSEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : *: : . . * .: . * :: : **.: : :: * : . . **:::. : : :: * : . * : . *.:: :. . ::* :: : . : : : :: *: : :* . : .:*..:.: * : .. * ::: :. *. :. ..* *.: ** . *: : :. : : . : . *. ::: : . . . .: . . *: *:: :* : : .*: : . * : *. : : :.: . : ", "identical_positions": 30, "similar_positions": 118, "identity": "3.01%" }, { "cls_id": "homologset.agr.MGI:1929083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JL59-1", "uniprot_id": "SCT1B_MOUSE", "id": "Q9JL59-1", "name": "Secreted and transmembrane protein 1b", "aln": "MLAYSVTSSGLFPRMLWALLLLAASLNAHNDVWDEPCCTEHEVSVNRGSRVVMACNISNNLRDVTIELVTSEKTSIIFNHTPPGNYSKDSWQLHIQGVQAQLVITDAQDKHSGNYSWKLHGFQAEFKNFNLTVN-------------------------------------AADRQKTEDLPVTKVPDKPPTAVRTEVI-IIIAIATTIIITGIGVFVWYKQFP-------VAPQIQMSVPCLIHGSPGIPYLTLPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PTB4-1", "uniprot_id": "E9PTB4_RAT", "id": "E9PTB4-1", "name": "", "aln": "MMVCWATYSGLFPRMLWALLLLAASLNAYNKEWDEPSCTVPEVSAKRGDRVVMACNISNTFRDVTITLTAGEETRTIFKKMPPGNYSKDSWQLQIQGGQAQLVITDAQDIHAGEYWWKLSGFQKNFTNFTLDVTGPQDQKEAKG---------------WKPLMFSDSQGLATDNQKPESLPVIAEP---QTAVRTKAVSVIIIITALTIIAGMSAFAWYKHRRSLKLRGYKFQQIQTPVPGLSHGSPGGPYLILP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WVN6-1", "uniprot_id": "SCTM1_HUMAN", "id": "Q8WVN6-1", "name": "Secreted and transmembrane protein 1", "aln": "MQTCPLAFPGHVSQALGTLLFLAASLSAQNEGWDSPICTEGVVSVSWGENTVMSCNISNAFSHVNIKLRAHGQESAIFNEVAPGYFSRDGWQLQVQGGVAQLVIKGARDSHAGLYMWHLVGHQRNNRQVTLEVSGAEPQSAPDTGFWPVPAVVTAVFILLVALVMFAWYRCRCSQQRREKKFFLLEPQMKVAALRAGAQQGLSRASAELWTPDSEPTPRPLALV--------FKPSPLGALELLSPQPLFPYAADP-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : .* ..: * :**:*****.* *. **.* ** **.. *...**:***** : .*.* * : : **:. .** :*:*.***::** *****..*:* *:* * *:* *.* : :..* *. ..*: *. . * :*:*: . : :: .. . * .* ** * ", "identical_positions": 67, "similar_positions": 57, "identity": "26.07%" }, { "cls_id": "homologset.agr.MGI:1929084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC63-1", "uniprot_id": "FBX3_MOUSE", "id": "Q9DC63-1", "name": "F-box only protein 3", "aln": "MAAVEAETGLLTLESLPTDPLLLILSFVDYRDLINCCYVSRRLSQLSTHDPLWRRHCKKYWLISEEEKAGKSQCWRSLFIETYSDVGRYIDHYAAIKKAWRDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKYCLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNNVVSGGFPIIRDQIFRYIHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSRDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRIYEYTSCTTFSTTSGYMEGYYTFHFLYFKDKVFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEAEEEEEE-ENDDSADMDESDESDADENESDEGEGEARRRRVFDVPIRRRRCSRLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABP9-1", "uniprot_id": "FBX3_RAT", "id": "D4ABP9-1", "name": "F-box only protein 3", "aln": "MAAVEAETGLLTLESLPTDPLLLILSFVDYRDLINCCYVSRRLSQLSTHDPLWRRHCKKYWLITEEEKARKNQCWKSLFIATYSDVGRYINHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKYCLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNNVVSGGFPIIRDQIFRYIHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSRDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRIYEYTSCTTFSTTSGYMEGYYTFHFLYFKDKVFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEAEEEEEE-ENDDSADMDESDESDEDENESDEGEGEERRRRVFDVPIRRRRCSRLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UK99-1", "uniprot_id": "FBX3_HUMAN", "id": "Q9UK99-1", "name": "F-box only protein 3", "aln": "MAAMETETAPLTLESLPTDPLLLILSFLDYRDLINCCYVSRRLSQLSSHDPLWRRHCKKYWLISEEEKTQKNQCWKSLFIDTYSDVGRYIDHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKYCLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRVYEYTSCTTFSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEEEEEEEDEDDDSADMDESDEDDE----------EERRRRVFDVPIRRRRCSRLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R287-1", "uniprot_id": "F1R287_DANRE", "id": "F1R287-1", "name": "", "aln": "----MATSIALSLDNLPSDPLLLVLSFLDFRDLISCSFVSRRLNELTGHNPLWKRLCQKHWLLSEADKTQRGLSWKDLFREYYADLGRYFDYYSTLKKAWDDLKNFLNQKCPRMIASLKEGVREDELDTIEAQIGCKLPNDYRCSYRIHNGQKLVVPGLMGSMALSNHYRSEDLLDIETAAGGFQQRKGMRQCLPLTFCFHTGLSQYMALETTEGRTRSEIFYQCPDQLAQDPSAIDMFITGSNFTEWFTSYVDNVVTGEYPIIRDQIFRYVHDKRCVATTGDITVSVSTSFLPELSSVHPPHFFFTYRIRIEMAKSALPEKACQLDSRYWKITNANGNVEEVRGPGVVGEFPVMTPGKVHEYASCTTFSTTSEYMEGHYTFHRLKNKEEVFDVSIPRFHMVCPPFRESVVRSSSVSEVSAPYDDENSSDTDDYEEGEMRGMNMAD--------------------------PGGRCPRHV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:*:.**:*****:***:*:****.*.:*****.:*: *:***:* *:*:**::* :*: :. .*:.** *:*:***:::*:::**** ***::*: :****: *****.**::**::*********:*******************:****************::*********:*:: *******:*******:*:*::***.:.*:*******:*::*:****** *:.**:******.***:* :**********:** .***************************:**********::.**************:****:*:****:*********:::**:::**:********* ****:**** * *:::*:*:******.**.** *:.* . .: ::* ..: :: *:.: .*: :* **.* .", "identical_positions": 292, "similar_positions": 117, "identity": "60.71%" }, { "cls_id": "homologset.agr.MGI:1929091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B4F781-1", "uniprot_id": "B4F781_RAT", "id": "B4F781-1", "name": "", "aln": "-MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKK---------VKTLSGNRMKSSQISKLQKEFKRHNSDAHST--------------TSSASPAQSPCYSNQSDEGSD------------------------TEMASSSNRTPVFS---------------------FLDLTYWKRQKICCGIIYKGR-FG--EVLIDTHLFKPCCSSK----------------KAAAEKP----------------------------------------------EEQAPAPLPISTQEW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8M1-1", "uniprot_id": "SHCAF_MOUSE", "id": "Q8C8M1-1", "name": "SIN3-HDAC complex-associated factor", "aln": "-MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKK---------VKTLSGNRMKSNQISKLQKEFKRHNSDAHST--------------TSSASPAQSPCYSNQSDEGSD------------------------TEMASSSNRTPVFS---------------------FLDLTYWKRQKICCGIIYKGR-FG--EVLIDTHLFKPCCSSK----------------KAAAEKP----------------------------------------------EEQGPAPLPISTQEW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP50-1", "uniprot_id": "SHCAF_HUMAN", "id": "Q9NP50-1", "name": "SIN3-HDAC complex-associated factor", "aln": "-MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKK---------VKTLSGNRIKSNQISKLQKEFKRHNSDAHST--------------TSSASPAQSPCYSNQSDDGSD------------------------TEMASGSNRTPVFS---------------------FLDLTYWKRQKICCGIIYKGR-FG--EVLIDTHLFKPCCSNK----------------KAAAEKP----------------------------------------------EEQGPEPLPISTQEW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JUX7-1", "uniprot_id": "A8JUX7_DROME", "id": "A8JUX7-1", "name": "Protein FAM60A", "aln": "-MFNFHKPRVYRSADGCCICRAKSSSSRFTASRKYEKESMQCFNLNEPRNGEICNACVLLVKRYKRLPIGSKRHWGHVVDARAGPGTKSMAKQKKRDNADAKSRAANGSGNSFLPEKFAKNRKSKERAATEAAAARPSSLSLSTSAVNRPSSTSPTSDHQHSDSNESYDDEQTLPANKPYQTRKRTAAAALATANESKEPNNKRPKLTGSYRRRQLVPQKNRRSVDNIPFFEENDLVRLEVCCGVVFQSLSLGSTYYIIDPELYKPCAKHQRIRHQQMQLQLQHQQAEAVNATPTPTTTPTVTTNSSPHTTQVQSKVPTIGPLKKHHLFCKRQSGSFPQGEIHSISPIPMSKTETDGQPLSPKPHSTLSLILKPTVQMQQQQPQSQAQSQVVSVGAASPSSLSSLSNCSTSSSVATKFNDNSSDSGFDEHVLERKSVSPPTQDECKLRGTTGGRVQLILVSGLPLAGQSQNLMLAGNEFTARIVQQREAGIAAATAAGAGTGTPSTGATPLKINVLGGSQGNSNKMRAIFNSASSIQHENGVTTIVPASSLAASNQTAAMNAIAPSTVTITPSSVGKKVTVPNPKFILLKPAKFVGPASANEVNTATLTAEPHAPPPPQAKIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1QLZ5-1", "uniprot_id": "F1QLZ5_DANRE", "id": "F1QLZ5-1", "name": "", "aln": "MRENFTQRRLPSRIRQSVSQYSKSTLSKMATRK---RSIVWSFFQAEDDRRVLCLLCMKTVLYFGHTTNMLRHLRTKHPSDFSSLDKRKPATDAVS--------KRNDSGCVEVTVLMDEQQVEVESVGEDGEMDG-------------AIKGILRAAAGEGTTEAEVVD------------------------EEVEGPVDEGDGKD---------------------IQEDEAPGNTRKWSSVWVHYRKLGQEPRALCLLCMEKIQHRS----------------STSNLIR----------------------------------------------HLQHKHPNEFAQLEDHPQKRPNKRKSDDPTRLTSSPTLSSNPTRSLIVSPKRDMRTPCSTSLDRYSGAKWSEGVR---------------ILERERELTEALRRVQQEEGRSIQLQKELLQQFREMDAERRVLQN-----QKCEQEQEHARLRKEREDLQQ----------EKSELQREREEIQKEREEFQKEKEELEKQKQELDTWKNSHAQGQTSGFYSC-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : :: . :**: *::: : :. .* * :* *: * : : . :: : . :. . :. . . ** . : : : . : :. . . . . . * * :. : : . . ..: : :* : : . .: . : * :: * ", "identical_positions": 16, "similar_positions": 63, "identity": "2.57%" }, { "cls_id": "homologset.agr.MGI:1929092", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9Q1-1", "uniprot_id": "M0R9Q1_RAT", "id": "M0R9Q1-1", "name": "RNA-binding protein 14", "aln": "------MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGAVRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPALAIQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLG-AAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGVQPSASALSTYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYSAQSAPYAAQQAASYSSQPAAYVAQPAAAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPG---SAYDGTGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C2Q3-1", "uniprot_id": "RBM14_MOUSE", "id": "Q8C2Q3-1", "name": "RNA-binding protein 14", "aln": "------MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGAVRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPALAIQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLG-AAYRAQPSASLGVGYRTQPMAAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGVQPSASALSTYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYSAQPSASYSAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASIGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPG---SAYDGTGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PK6-1", "uniprot_id": "RBM14_HUMAN", "id": "Q96PK6-1", "name": "RNA-binding protein 14", "aln": "------MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLG-AAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPG---NAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q1B8-1", "uniprot_id": "A0A8M9Q1B8_DANRE", "id": "A0A8M9Q1B8-1", "name": "RNA-binding protein 14", "aln": "MDKGHTVKLFVGNLA-LDTTQEELSAIFESYGQVVSCSVLRQFAFVHLQGEGAAERAIRELNGREFK-GRNLVVEESRGRPLHSTKVFVGNLSSMCTTEDLQELFQTFGKVLECDKVKGYAFVHMENKEDALQAIEALHGTSFKGRPLSVELSKVQPSKQTPTGKIPCVSCGKQGHYAGECP--AGKPTLEQYQSQAAVLAAAAAAAAGLPLQVQQSVHNSVYNTSTFDPTYAALTGLTAAGARAEGGAAVAPAVYGALASQVYGTAVANQLYGGSVANQALN------------------SSAAAAAAQAYGTVNPALYGQMTSGAVAAAAAAAAAYGPQVGFLVYTQAVGNPVFLTAAPSMEVPAGAAAVN--------PAYTVAPALYSATPAYGALGAADPAAIFEAARAHYFAQGQQVLAEQQQASSKS----------------GERDRSPLRRSAPLLPDPVMKPFIYQRAKRRALLPTPAGREEAAAQEDDPVARYYAEYYQQYQQLQQYPQYQYAYPAHSALAAMSALQSLPGVSAQQVATLDSLRPVLPAAPVPAAAAIAMATPRVYEPPPIPPSHKEPLLRRPELALHTPETPFR-------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:****: *** ***:*:* .** *:**:*::******:: :..* ***. *:*:*:: ** **** ** ***:: *:****:*: **:::*:.**: *:*:*** **.*******:: ** ** *:*...**: :.****. .* . . . . * * * .* .: :**. . :.. . * * . ..* . *. .:*.* .* **: ..::. *.* * .* *.. .* ...*. : .****:: .** .:*: . : *. ****:: :**.* . *. .. **.* * *.*:: * :* . .* *.* .* .:*. . ** :.* : : . * ** ** .* .: . : ::*: . :*.: : : . .: . . .**. ..: *. * . * : ::*** * *. * .:*. . . . .: *:** ::*: * :. . **.::.. * *. : . * . ", "identical_positions": 165, "similar_positions": 174, "identity": "24.3%" }, { "cls_id": "homologset.agr.MGI:1929093", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCZ9-1", "uniprot_id": "HYPDH_MOUSE", "id": "Q8VCZ9-1", "name": "Hydroxyproline dehydrogenase", "aln": "----------------MIWTRLPLYGPSKPSTGGWQP----------LRFDG-GAFHVKGTAELARALLVLRLCAWPPL-VTHGLAFQAWSQRLLGSRLSGALLRASIYGQFVAGETAEEVRNCVGQLQALGLQPLLAVPTEEEPDSTAKTSEVWYEENLSAMLRCVDLSRALVDAHGPARNSLMQLKVTALASTRLCKELSAWIQRPRGSSELSPERLAEAMDSGRNLQLSCLSTEQNQHLQASLSRLHRVAQHARAKCVRLLVDAEYTFINPALSLLVAALAVRWNSPEEGGPWVWNTYQAYLKDTHQRLEQDAEAAHKAGLAFGVKLVRGAYLDKERSMTQLQGKEDCTQPDYEATSRSYSRCLELMLRCVSNHGPP---CHLMVASHNEESVRQATKRMWELG-IPLDG-PVCFGQLLGMCDHVSLALGQAG--YMVYKSIPYGCLEEVIPYLIRRAQENRSVLQG--ARREQALLSQELWRRLLG---RTA-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2V057-1", "uniprot_id": "HYPDH_RAT", "id": "Q2V057-1", "name": "Hydroxyproline dehydrogenase", "aln": "----------------MIWTRLPLYGHSKPSTGGWQP----------LRFDG-GAFHLKRTAELARALLVLRLCAWPPL-VTHGLAFQAWSQRLLGSRLSGALLRASIYGQFVAGETAEEVRGCVQQLQAIGLQPLLAVPTEEEPDSAAKTSEAWYEGNLSAMLHCVDLSRAVADAHGPARNSLMQLKVTALTSPRLCKELSAWIQRPRGSSELRPERLAEAMESGRNLQLSCLSTEQNQHLQASLSRLHRVAQHARAQDVRLLVDAEYTFINPALSLLVAALAMRLDSSEEEGPWVWNTYQAYLKDTHERLERDAKAAHEAGLAFGVKLVRGAYLDKERSVTQLHGKEDCTQPDYEATSRSYSRCLELMLRRVSNHGPR---CHLMVASHNEESIRQATRRMWELG-IPLDG-PVCFGQLLGMCDHVSLALGQAG--YMVYKSIPYGCLEEVIPYLIRRAQENRSVLQG--ARREQALLSQELWRRLLG---RTA-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UF12-1", "uniprot_id": "HYPDH_HUMAN", "id": "Q9UF12-1", "name": "Hydroxyproline dehydrogenase", "aln": "----------------MLRTCYVLCSQAGPPSRGWQS----------LSFDG-GAFHLKGTGELTRALLVLRLCAWPPL-VTHGLLLQAWSRRLLGSRLSGAFLRASVYGQFVAGETAEEVKGCVQQLRTLSLRPLLAVPTEEEPDSAAKSGEAWYEGNLGAMLRCVDLSRGLLEPPSLAEASLMQLKVTALTSTRLCKELASWVRRPGASLELSPERLAEAMDSGQNLQVSCLNAEQNQHLRASLSRLHRVAQYARAQHVRLLVDAEYTSLNPALSLLVAALAVRWNSPGEGGPWVWNTYQACLKDTFERLGRDAEAAHRAGLAFGVKLVRGAYLDKERAVAQLHGMEDPTQPDYEATSQSYSRCLELMLTHVARHGPM---CHLMVASHNEESVRQATKRMWELG-IPLDG-TVCFGQLLGMCDHVSLALGQAG--YVVYKSIPYGSLEEVIPYLIRRAQENRSVLQG--ARREQELLSQELWRRLLPGCRRIPH----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QIL9-1", "uniprot_id": "A0A8M9QIL9_DANRE", "id": "A0A8M9QIL9-1", "name": "Proline dehydrogenase", "aln": "----MCSLLRPPALSRLICVRLKTMAASQFPAAKRSGELNNPSPAAYLRFEDPQAFRVKSLWELIRALGVFRLCSFPVL-VNNCGKLMSFSRRVLGKRCFCMVLRPSVYAQFVAGETEGEIADSMQKMSSLGLHPMLAVPIEEDLG--ESTGEKRYDDNLSAMLECVFMS----HSNGWSNNPMMQLKITALVSPELCVKLTSLLKTELYDLNL----LVKAMD-GEEVLFPGLTESENTHLLFGLRRLNKIGEAS-VNKVRVLVDAEYTYMNPALSLITMAMMKKFN---QQSAWIWNTYQCYLKESRNLLLDAVQTSINQSFCFGVKLVRGAYMDKERKLAEKEGRTDPIHESWEHTNDSYNGCLELMLKLIAEKPER---YMMIVATHNEESVRRAVTHMAELG-LHRDGNSVCFGQLLGMCDHVSLTLAQHG--FSVYKSVPYGSVDDTLPYLVRRAQENRTVLQG--IRKERDLLRQELHRRLKEKISRSTKRNCAGNQTKGQVGKDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09368-1", "uniprot_id": "PUT1_YEAST", "id": "P09368-1", "name": "Proline dehydrogenase, mitochondrial", "aln": "MIASKSSLLVTKSRIPSLCFPLIKRSYVSKTPTHSNTAANLMVETPAANANGNSVMAPPNSINFLQTLPKKELFQLGFIGIATLNSFFLNTIIKLFPYIPIPVIKFFVSSLYCGGENFKEVIECGKRLQKRGISNMMLSLTIENSEGTKSLSSTPVDQIVKETISSVHNILLP-----NIIGQLESKPINDIAPGYIALKPSALVDNP---HEVLYNFSNPAYKAQRDQLIENCSKITKEIFELNQSLLKKYPERKAPFMVSTIDAEKYDLQENGVYELQRILFQKFNPTSSKLISCVGTWQLYLRDSGDHILHELKLAQENGYKLGLKLVRGAYIHSEK------NRNQIIFGDKTGTDENYDRIITQVVNDLIINGEDSYFGHLVVASHNYQSQMLVTNLLKSTQDNSYAKSNIVLGQLLGMADNVTYDLITNHGAKNIIKYVPWGPPLETKDYLLRRLQENGDAVRSDNGWPLIKAIAKSIPKRVGL-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. . :. .: :: ::* .* : : : : * .:: : . : .**. *: . :: .: :: *: . .. : : : .* : . :. :.. :. : :: : :: * . .: . . : : . *:: : * : :* : .: : : : : . .*:* *::: : : : : . . :*:*******:..*: . : . *. .*. : :: : : ::**:** :* .. : . : :******.*:*: * : * :*:* :. **:** *** .::. : :.: :*: ", "identical_positions": 51, "similar_positions": 135, "identity": "9.94%" }, { "cls_id": "homologset.agr.MGI:1929094", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBX1-1", "uniprot_id": "D3ZBX1_RAT", "id": "D3ZBX1-1", "name": "Galectin", "aln": "---------------------------------------------------------------------------------------------MSTDEHLDPIP------------------DSFILQPPVFHPVIPYVTTIFGGLYAGKMIMLQGVVPRHARRFQVDFQC--GCCLHPRPDVAFHFSPRFYTVKPHVICNTLQGGLWQKEVR--WPGIALQKGASFLILFLFDNEEVKVSVNGQHFLHYRYRLPLSRVDTLDISGDILVKAVG--------------------------FLNISPFVEGSREYPVGYPLLLYSPR----------------LEVPCSRALPRG--LWPGQVIVVRGLVLKEPKDFTLSLRDGATHVP-----------------VTLRASFTDRTLAWVSSWGRKKLISAPFLFYPQRFFEVLLLCQEGGLKLALNGHGLGATSLDQKALEQLRDLRISGSVHLYCVHC--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VD1-1", "uniprot_id": "LEG12_MOUSE", "id": "Q91VD1-1", "name": "Galectin-12", "aln": "---------------------------------------------------------------------------------------------MSTDEHLDPIP------------------DSFILQPPVFHPVIPYGTTIFGGLYAGKMVTLQGVVPLHARRFQVDFQC--GCCLHPQPDVAFRFSPRFYTVKPHVICNTHQGGLWQKEIR--WPGVALQRGDSFLILFLFENEEVKVSVNGQHFLHYRYRLPLSRVDTLDISGDILVKAVG--------------------------FLNINPFVEGSREYPVGYPFLLYSPR----------------LEVPCSRALPRG--LWPGQVIVVRGLVLKEPKDFTLSLKDGTTHVP-----------------VTLRASFTDRTLAWVSSWGRKKLISAPFLFHPQRFFEVLLLCQEGGLKLALNGQGLGATSLDQKALEQLRELRISGNVHLYCVHC--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DT0-1", "uniprot_id": "LEG12_HUMAN", "id": "Q96DT0-1", "name": "Galectin-12", "aln": "-----------------------------------------------------------------------MSQPSGGRAPGTRIYSWSCPTVMSPGEKLDPIP------------------DSFILQPPVFHPVVPYVTTIFGGLHAGKMVMLQGVVPLDAHRFQVDFQC--GCSLCPRPDIAFHFNPRFHTTKPHVICNTLHGGRWQREAR--WPHLALRRGSSFLILFLFGNEEVKVSVNGQHFLHFRYRLPLSHVDTLGIFGDILVEAVG--------------------------FLNINPFVEGSREYPAGHPFLLMSPR----------------LEVPCSHALPQG--LSPGQVIIVRGLVLQEPKHFTVSLRDQAAHAP-----------------VTLRASFADRTLAWISRWGQKKLISAPFLFYPQRFFEVLLLFQEGGLKLALNGQGLGATSMNQQALEQLRELRISGSVQLYCVHS--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPI6-1", "uniprot_id": "Q9VPI6_DROME", "id": "Q9VPI6-1", "name": "Galectin", "aln": "MTAIILLACHSVRELVDLSDALWQNTFNIERSLNYYRIKRRLELFRFHCRELWLRQVSKTSDPMHRKAGIDFAAIEAGADCVLNMDAFDDTTTELHKRFLQAEGTRPFPSDCISGIEVVDGNEFKASFYEYADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNNDS-----RDVALHINPRLP--QNYIVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVKGDVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNTQSDSSPKRNNSSNDLGLTLPYYG-ALPPNSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYKVSP-EVVDTVYIQGDVKLWNVTLEKNQMIKGKNMRVYQN----PWFFSE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPI7-1", "uniprot_id": "Q9VPI7_DROME", "id": "Q9VPI7-1", "name": "Galectin", "aln": "------------------------------------------------------------------------------------MSVYPGACTVALRRVMDAMS---------------------LFYEKRSEAHRRKHFKVIQCPRPGLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLP--QNYITRNSRLKGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYVSEYPIRLTHS--------LPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKFLYQPS-----LPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLFHFKYQMRP-ECVDIVNIRGDIKLWEVAIQGNTTYKKPKVRSAMERAISAWKRAEIPQLQI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::. .. : * . . * : ..:* ::: .. *: :::..*: : :: *: . * * . * :* .* : .*. : :**** ** : :*:* : : : **: : : . . . : .: * :* * * : :.* * *: * : ::. * : :. * . * . : * * : : . :: :* : : . . . * : : * *.::*: * ", "identical_positions": 41, "similar_positions": 85, "identity": "7.85%" }, { "cls_id": "homologset.agr.MGI:1929095", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1Z0-1", "uniprot_id": "USO1_MOUSE", "id": "Q9Z1Z0-1", "name": "General vesicular transport factor p115", "aln": "MNFLRG----VMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEE----------------------LEENSTRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQIILVSPMGVSRLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKTNNSNQNFFKEGSYIQRMKPWFEVGE---ENSGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRP-----------------AIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNEKGQGEIVATLLPSTIDATGNSVSAG--------------------------------------QLLCGGLFSTDSLSNWCAAVALAHALQGNATQKEQLLRVQLATSIG-----NPPVSLLQQCTNILSQ---GSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEE-EQLVQGLCALLLGISIYFNDNSLENYTKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQK------PQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEED----KKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQLQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHGDGAQVNGIQPEEISRLREEIEELKSQQALLQGQLAEKDSLIENLKSSQASGMSEQ----------------ASATCPPRDPEQVAELKQELTALKSQLCSQSLEITRLQTENCELLQRAETLAKSVPVEGESEHVSAAKTTDVEGRLSALLQETKELKNEIKALSEERTAIQKQLDSS-----------NSTIAILQTEKDKLDLEVTDSKKEQDDLLVLLADQDQ-------KILSLKSKLKDLGHPVEEED--ESGDQEDDDDEIDDGDKDQDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41542-1", "uniprot_id": "USO1_RAT", "id": "P41542-1", "name": "General vesicular transport factor p115", "aln": "MNFLRG----VMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEE----------------------VEENSTRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQIILVSPMGVSKLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKAWFEVGD---ENPGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRP-----------------AIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNEKGQGEIVATLLPSTIDATGNSVSAG--------------------------------------QLLCGGLFSTDSLSNWCAAVALAHALQGNATQKEQLLRVQLATSIG-----NPPVSLLQQCTNILSQ---GSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEE-EQLVQGLCALLLGISIYFNDNSLENYTKEKLKQLIEKRIGKENYIEKLGFISKHELYSRASQK------PQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEED----KKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQLQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHSDGAQVNGIQPEEISRLREEIEELRSHQVLLQSQLAEKDTVIENLRSSQVSGMSEQ----------------ALATCSPRDAEQVAELKQELSALKSQLCSQSLEITRLQTENSELQQRAETLAKSVPVEGESELVTAAKTTDVEGRLSALLQETKELKNEIKALSEERTAIQKQLDSS-----------NSTIAILQTEKDKLYLEVTDSKKEQDDLLVLLADQDQ-------KILSLKSKLKDLGHPVEEED--ESGDQEDDDDELDDGDRDQDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60763-1", "uniprot_id": "USO1_HUMAN", "id": "O60763-1", "name": "General vesicular transport factor p115", "aln": "MNFLRG----VMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNEEEEE----------------------VEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIISEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGD---ENSGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRP-----------------AIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGNSVSAG--------------------------------------QLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIG-----NPPVSLLQQCTNILSQ---GSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEE-EQLVQGLCALLLGISIYFNDNSLESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQK------PQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEED----KKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQ----------------SSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSS-----------NSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQ-------KILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3N6-1", "uniprot_id": "USO1_DROME", "id": "Q9W3N6-1", "name": "General vesicular transport factor p115", "aln": "MEFLKSGIKTVLGSTEPGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQGMPPLVQVLQNDGQDAEIISYALDTLCNVVTSEEFDE----------------------EADNPT-VSVNVGEQFTEMFIKTPEHVTLVMGYLDEYDFRVRRAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVLLLLIELTKGNSNIQKIVAFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKEGSYIQRLSPMFELSQDA-EEVGWSPQKVSNFHCLLQVVRALVTPSNQQQVVAACQRVMQKSRLLHALCEILMSSGVPADILTETINAVAEVVRGDRDNQDELGRVMAPSSPPRP-----------------AIVVLLMSMINEKQLLALRCAVLYCFECFLYRNADGQRAVVQTLLPSSASDVS-ALSTG--------------------------------------QLLCTGLFSTDALANWFSAVALMHSLVENVALKEELLRVLLATPGG-----QKPITLLEQCTNLMQQE--RYRLQSKVGLLMLLSLWLAHCPGAVKALLETQGTMAYLTAQLCSNEHDEREFLVQGMCAFLMGLCIQFNDNSLPGQKREDISQLIIKRIGQESFCSKLAEVSRHEAYSRACKQ------AQIRAKSAGELLLDFEYCKLYKGLEALIAKLVSGFDVDG----IELTELTLSSEAS-ALVSQYKGIIRGMDAQIQALQQSSKELEQENAELKEKLGEEQSLKAQLLDQNTLLKAQLG-------------------------------------------------------ASTGQVQSAQ----------------GAEATPPNE--------EELNAARYQAN-------------------------------------------------MYFAENIRLTKELETLRQQLSAEKQSADAA-----------QDSLAAMQ--------------KDQEDLLELLADQEA-------KLTRYEEAGSTNTLPTSNVA--PSVPAAGGGSPIPSGTASR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25386-1", "uniprot_id": "USO1_YEAST", "id": "P25386-1", "name": "Intracellular protein transport protein USO1", "aln": "MDIIQG-------LIQQPKIQSVDETIPTLCDRVENSTLISDRRSAVLGLKAFSRQYRESVIASGLKPLLNTLKRDYMDEDSVKAILETILILFIRGDGHDDLTRGWISQQSRLQNGKYPSPLVMKQEKEQVDQFSLWIADALTQSEDLIHLLVEFWEIDNFHIRLYTIQLLEAVMATRPLKARSALISLPTSISTMVSLLDDMHEPIRDEAILLLMAVVNDSPHVQKLVAFENIFERLFSIIEEEGGLRGSLVVNDCLSLINNILKYNTSNQTLFLETGNLPKLAHLLSEPISQDEVFFWNDQRIVNINTALDIVSLTVEPGN--TVTTKHQNALLDSSVLMVVLRLAFFHNIPKKVRPVALLTAANMVRSNEHAQLEFSKIDVPYFDPSLPVNSTANGGPIKLIPVVSILINWMLYANSVHTFDTRVACSRLLKAYFMDNFDLQRDFLLKQVQLCNNSTNNVGDNAKENGGSNKSDKESDSDKDTDGKDGTEYEGSFKANLFEVLLNYDAELNLNPFKLFFTTDIFMFFFQQDHKYSEELREITRNVTTGNDLEDEEPLKAIQTISELLTTSLTAADIRIPISYLTFLIYWLFGDFKATNDFLSDKSVIKSLLSFSYQIQDED--VTIKCLVTMLLGVAYEFSSKESP-FPRKEYFEFITKTLGKDNYASRIKQFKKDSYFSKVDMNEDSILTPELDETGLPKVYFSTYFIQLFNENIYRIRTALSHDPDEEPINKISFEEVEKLQRQCTKLKGEITSLQTETESTHENLTEKLIALTNEHKELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSDEEDDEEDDEEDEEEGQVA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 128, "similar_positions": 307, "identity": "7.1%" }, { "cls_id": "homologset.agr.MGI:1929096", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZW62-1", "uniprot_id": "D3ZW62_RAT", "id": "D3ZW62-1", "name": "", "aln": "MKPMLKDFSNLLLVVLCDYVLGEADYLVLREPVHVALSDRTVSVGFHYLGDVNGTLRNVTVMLWEANTNRTLTTKYLLTNQAQGTLQFECFYFKEAGDYWFVMIPEETDNGTRVPLWEKSASLKVEWPVFHIDLNRTAKAAEGTFQVGIFTSQPLCLFPVDKPDLLVDVIFKDSLPEARTSLGQPLEIRASKRTRLTQGQWVEFGCAPLGVEAYVTVMLRLLGQDSVIASTGPIDLAQKFGYKLMMAPEVRCESVLEVMVLPPPCVFVQGVLAVYKEAPKAPEERTFQMAENRLPLGERRSVFNCTLFDVGKNKYCFNFGILKKSHFSAKG-CMLIQRNIETWGPWQPWSPCSTTCGDAVRERRRTCVTSFPSRPSCSGKPSETSPCSLEECAVFRPPDPSP----DPEKYNNVVTVTGISLCLFIIFATVLITLWRRFGRAPKCSTPARHNSIHSPGFRKNSDEENICELSEPRGSFSDAGDGPRGSPGDTGIPLTYRCSASAPPEDEASGSESFQSNAQKIIPPLFSYRLAQQQLKEMKKKGLTETTKVYHVSQSPLTDTVVDATASPPLDLECPEEAAASKFRIKSPFLDQPGAGPGERPPSRLDGVLPPPSCAVSPSQTLIRKSQMRSTGGRDGSSERGHCRSSLFRRTASFHETKQARPFRERSLSALTPRQAPAYSSRMRTWEQMEDRGRPPSRSAHLLPERPEHFQGAAGRASSPLGPLSKSYTVGHPRRKPDPGDRQAGLVAGAAAEKMEPHRAHRGPSPSHRSASRKQTSPVFLKDSYQKVSQLSPSHFRKDKCQSFPIHPEFAFYDNTSFRLTEAEQRMLDLPGYFGSNEEDETTSTLSVEKLVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM61-1", "uniprot_id": "THSD1_MOUSE", "id": "Q9JM61-1", "name": "Thrombospondin type-1 domain-containing protein 1", "aln": "MKPMLKDFSNLLLVVLCDYVLGEAEYLLLQEPVHVALSDRTVSVGFHYLSDVNGTLRNVSVMLWEANTNRTLTTKYLLTNQAQGTLQFECFYFKEAGDYWFVMIPEVTDNGTQVPLWEKSAFLKVEWPVFHIDLNRTAKAAEGTFQVGVFTTQPLCLFPVDKPDMLVDVIFTDRLPEARASLGQPLEIRASKRTKLTQGQWVEFGCAPVGVEAYVTVMLRLLGQDSVIASTGPIDLAQKFGYKLMMAPEVTCESVLEVMVLPPPCVFVQGVLAVYKEAPKRPEERTFQVAENRLPLGERRTVFNCTLFDVGKNKYCFNFGIVKKGHFSAKE-CMLIQRNIETWGPWQPWSPCSTTCGDAVRERRRLCVTSFPSRPSCSGMSSETSPCSLEECAVFRPPGPSPVSPQDPVKSNNVVTVTGISLCLFIIFATVLITLWRRFGRAPKCSTPVRHNSIHSPGFRKNSDEENICELSEPRGSFSDAGDGPRGSPGDTGIPLTYRCSASAPPEDEASGSESFQSNAQKIIPPLFSYRLAQQQLKEMKKKGLTETTKVYHVSQSPLTDTVVDATASPPLDLECPEEAAASKFRIKSPFLDQPGAGTGERPPSRLDGIVPPPGCAVSPSQTLIQKSQIRSTGGRDGSSERCHSRSSLFRRTASFHETKQSRPFRERSLSALTPRQVPAYSSRMRTWDQMEDRCRPPSRSTHLLPERPEHFQG-AGRTSSPLGPLSKSYTVGHPRRKPDPGDRQAGLVAG--AEKMEPHRAHRGPSPSHRSASRKQSSPIFLKDSYQKVSQLSPSHFRKDKCQSFPIHPEFAFYDNTSFRLTEAEQRMLDLPGYFGSNEEDETTSTLSVEKLVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS62-1", "uniprot_id": "THSD1_HUMAN", "id": "Q9NS62-1", "name": "Thrombospondin type-1 domain-containing protein 1", "aln": "MKPMLKDFSNLLLVVLCDYVLGEAEYLLLREPGHVALSNDTVYVDFQYFDGANGTLRNVSVLLLEANTNQTVTTKYLLTNQSQGTLKFECFYFKEAGDYWFTMTPEATDNSTPFPWWEKSAFLKVEWPVFHVDLNRSAKAAEGTFQVGLFTSQPLCPFPVDKPNIVVDVIFTNSLPEARRNSRQPLEIRTSKRTELAQGQWVEFGCAPLGPEAYVTVVLKLLGRDSVITSTGPIDLAQKFGYKLVMVPELTCESGVEVTVLPPPCTFVQGVVTVFKEAPRYPGKRTIHLAENSLPLGERRTIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSPSPLQPQGPVKSNNIVTVTGISLCLFIIIATVLITLWRRFGRPAKCSTPARHNSIHSPSFRKNSDEENICELSEQRGSFSDGGDGPTGSPGDTGIPLTYRRSGPVPPEDDASGSESFQSNAQKIIPPLFSYRLAQQQLKEMKKKGLTETTKVYHVSQSPLTDTAIDAAPSAPLDLESPEEAAANKFRIKSPFPEQPAVSAGERPPSRLDLNVTQASCAISPSQTLIRKSQARHVGSRGGPSERSHARNAHFRRTASFHEARQARPFRERSMSTLTPRQAPAYSSRTRTCEQAEDRFRPQSRGAHLFPEKLEHFQEASGTRG-PLNPLPKSYTLGQPLRKPDLGDHQAGLVAG--IERTEPHRARRGPSPSHKSVSRKQSSPISPKDNYQRVSSLSPSQCRKDKCQSFPTHPEFAFYDNTSFGLTEAEQRMLDLPGYFGSNEEDETTSTLSVEKLVI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************:**:*:** *****: ** *.*:*:...*******:*:* *****:*:*********:****:**************.* ** ***.* .* ***** *********:****:***********:**:**** ******:::*****.: ***** . ******:****.*:***********:* ******:*:***:****:***************:*.**: *** :** ******.*****::*:****: * :**:::*** *******::*******:*******:*** .:.***** ******* **** ***** **:****.****** *:***** * *.* . *:* *******.*:*..*** .* * **:*************:*************..*****.********.*************** ******.**** ************* *...****:*****************************************************.:**:.*.*****.******.******** :**....********* :. ..**:*******:*** * .*.*.*.*** *.*.: *********::*:*******:*:*****.****** ** :* *** ** **.:**:**: **** :* . **.**.****:*:* **** **:******* *: *****:*******:*.****:**: **.**:**.****: ********* ************ **********************************", "identical_positions": 651, "similar_positions": 132, "identity": "76.14%" }, { "cls_id": "homologset.agr.MGI:1929099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14590-1", "uniprot_id": "ZN235_HUMAN", "id": "Q14590-1", "name": "Zinc finger protein 235", "aln": "--------MTKFQEAVTFKDVAVAFTEEELGLLDSAQRKLYRDVMLENFRNLVSVGHQSFKPDMISQLEREEKLWMKELQTQRGKHSGDRNQNEMATLHKAGLRCFSLGELSCWQIKRHIASKLARSQDSMINIEGKSSQFPKHHDSPCQVGAGESIQASVDDNCLVNHIGDHSSIIENQEFPTGKVPNSWSKIYLNETQNYQRSCKQTQMKNK-LCIFAPYVDIFSCISHHHDDNIVHKRDKVHSNSDCGKDTLKVSPLTQRSIHTGQKTYQGNECEEAFNDSSSLELHKQVHLGKKSPACSTHEKDTSYSSGIPVQQSVRTGKKRYWCHECGKGFSQSSNLQTHQRVHTGEKPYTCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGKGFSRSTDLNIHCRVHTGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASSFQSHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQRVHTGEKPYKCEECGKGFSQASNLQAHQSVHTGEKPFKCDACQKRFSQASHLQAHQRVHTGEKPYKCDTCGKAFSQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPYTCQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQRVHTGGNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0U1RPC5-1", "uniprot_id": "A0A0U1RPC5_MOUSE", "id": "A0A0U1RPC5-1", "name": "", "aln": "MHAGMETFWRLFQEAVTFRDVAVVFSEEELGLLDAAQRKLYHDVMLENFRNLLAVGGQ--------------------------------VPNKMENLHTTGVRCLSLGQLPCGHMASHDANKLARAPEGVINTQGMVSYFPEQCHFSCHRGPEEPPWASKDNGCLEILTNDHSSITESQKFLSGIAQCSWSKKHLSKRQNYQKHCVQTPVKTKPRRLLAPGIDRMSCVSHQ-DNNTLHKGDKGQSNSDFDKLTFPVSPVTPHHVYTERKSYKCSKAQEAFIDRPTLELHQQDLVGKKSPVRSTYEVSRHSS----IQKSVHAGTKRYWCHECGKAFSQSSALQTHRRVHTGEK----------------------------PYRCDSCGK----------------------------AFTQWSVLHAHQRIHTGEKPYKCGDCGRRFRFSSNLHIHQRVHTGEKPYKCHVCGKCFRFRF--YSHQRVHTGEKPYKCDECGKGFTSASNVKVHQRVHTGVKPFCCNVCGKCFSRSFHLHTHQRVHTGEKLYKCDACGKAFSQRSSLQVHRLIHTGEKPYKCEECGKGFTSASSFQGHQRVHTGEKPFHCDVCGKDFSRSSYLQIHQRMHTGEKPYKCDSCGKAFSQRAHLQVHQRTHTGEKPFKCEECGKEFRQRSGLSSHQIVHKEEKPYTCWECGKGFSQPSLFERHRRVHTGERPYICGTCCKGFSQRSHLVKHQRVHSAANL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:****.*:********:******:**********::** * *:* .**.:*:**:***:*.* :: * *.****: :.:** :* * **:: . .*: *. *. ** *:.** .***** *.*:* :* . **** :*.: ****: * ** :*.* ::** :* :**:**: *:* :** ** :**** .* *: ***:* : ::* :*:*: .:.:*** * .:****:* :*****. **:* . * :*:**::*.**********.***** ****:******* ********* .*** * *:**:***************:** ***** ****** ******. ***** : * :**************:******:***..: ******* *** ****** **:* ::::********* ***:.*** *. .*: *: :****************:.**.:*.** ********:**.* * **::*:** ***:**********:********::***** **************** :***:** **. ****** :*******.* *. *:***********..***********: *****:..**", "identical_positions": 416, "similar_positions": 130, "identity": "55.69%" }, { "cls_id": "homologset.agr.MGI:1929100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88811-1", "uniprot_id": "STAM2_MOUSE", "id": "O88811-1", "name": "Signal transducing adapter molecule 2", "aln": "MPLFTAN-PFEQDVEKATNEYNTTEDWSLIMDICDRVGSTPS-GAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRSVIKNKAHPKVCEKLKSLMVEWSE-EFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAAAKNGTSLNKN-------KEDEDIAKAIELSLQEQKQQY-------TETKALYP------------PAESQLNN---KAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVE---------TATVDKLNVIDDDVEEIKKSEP-------EPVYIDEGKMDRALQILQSIDPKESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVN-----------------------------EAPVYSVYSKLHP---------AHYPPAAAGVPVQTYPVQSHGGNYLGHGIHQV-------SVAQNYNLGPDPMGSLRSLPP--------------NMN-SVTAHTVQPP---------------YLSTGQDTVSNPSYMNQSSRLQAAAGTAAYTQPVGMSTDVSSFQNTASGLPQLAGFPVAVP------------APVAAQPQ-ASYHQQPLL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XHY7-1", "uniprot_id": "STAM2_RAT", "id": "Q5XHY7-1", "name": "Signal transducing adapter molecule 2", "aln": "MPLFTAN-PFEQDVEKATNEYNTTEDWSLIMDICDRVGSTPN-GAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSE-EFQKDPQFSLISATIKAMKEEGVTFPSAGSQTVSAAAKNGASLNKN-------KEDEDIAKAIELSLQEQKQQY-------PETKALCP------------PAESQLSN---KVARRVRALYDFEAVEDNELTFKHGEIITVLDDSDANWWEGENHRGAGLFPSSFVTTDLSTEVE---------AATVDKSNVIDDDVEEIKKSEP-------EPVYIDEGKMDRALQILQSIDPKDPKPDSQDLLDLEDICQQMGPMIDEKLEEIDRRHSELSELNVKVLEALELYNKLVN-----------------------------EAPMYSVYSKLHP---------APYSATAAGVPVQTYPVQSHGGNYLGHGIHQV-------PVAQSYNLGPDPMGSSRSLPP--------------NMN-SVTAHTIQPP---------------YLSTGQDAVSNPSYMTQSSHLQAAAGTAAYTPAMGVSADLSSFQSTASGLPQLAGFPVAVP------------VPPAPQPQ-ASYHQQPLL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75886-1", "uniprot_id": "STAM2_HUMAN", "id": "O75886-1", "name": "Signal transducing adapter molecule 2", "aln": "MPLFTAN-PFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPN-GAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSE-EFQKDPQFSLISATIKSMKEEGITFPPAGSQTVSAAAKNGTSSNKN-------KEDEDIAKAIELSLQEQKQQH-------TETKSLYP------------SSEIQLNN---KVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTTNLNIETE---------AAAVDKLNVIDDDVEEIKKSEP-------EPVYIDEDKMDRALQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLVN-----------------------------EAPVYSVYSKLHPP--------AHYPPASSGVPMQTYPVQSHGGNYMGQSIHQV-------TVAQSYSLGPDQIGPLRSLPP--------------NVNSSVTAQPAQTS---------------YLSTGQDTVSNPTYMNQNSNLQSATGTTAYTQQMGMSVDMSSYQNTTSNLPQLAGFPVTVP------------AHPVAQQH-TNYHQQPLL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WI00-1", "uniprot_id": "A8WI00_DANRE", "id": "A8WI00-1", "name": "", "aln": "MPLFGQN-PFDQDVEKATSETNTVEDWGLIMDICDRVGTAPN-GAKDCLRSIMKRVNHKVPHVAMQALTLLGACVANSGKIFHLEICSREFASEVRGVLN-RAHPKVNEKLKALMAEWAE-DFQKDPQLSLIGATIKSLKEEGVTFPTANPQSSSTKPSSTPATSRA-------SADDDLAKAIELSLQEQKQQ--------TETRPLTV------------IADPPYNTNGGKESRKVRALYDFEAAEDNELTFKAGELVIILDDSDPNWWKGENHRGVGLFPSNFVTTNLNAEPD---------PVMYVEKTVVPEEPIVEVKAEP-------EPVYIDEEKMDKTLYLLQNTDPADATPDGPELLTLEDACEKMNPLIDEKLQEIDRKHSELSELNVKVLEALELYNQLMN-----------------------------EAPLYNAYSKMQSLQ-------GTYPAAPPHLSMQGYQPS---GAYMSAG------------VPQGYSLT-DQAGPLCSMPP--------------SINSVAPSQPAQPS---------------YISG----PMNAPYVN-----QAPGGPTPYPPQMGVAMDMSAYQNANPGLPPTS-YPMSAP------------AQPAPQQQQAAFYQQPLL--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XTL2-1", "uniprot_id": "Q9XTL2_DROME", "id": "Q9XTL2-1", "name": "", "aln": "MGIFGQSSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPR-LAKDCLKAVMRRMGHTDPHVVMQAITLLDALSNNCGKPLHLEVASRDFETEFRRLLA-KAQPKVSLKMRQVLKNWAENDYKNDRELDLIPALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTEAAAAAAAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAELERVDRKHAQLTQLSSDLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGFPPAQNYPGMHSMPYGPVPNPPTSAPSQAPGAPGGYLGQPQGQVPLPYQNGHAAQMNSLPAHLTQPTGTAPMPQPIYTQPTPVTTQQQQQPLPQHPQQPPQQQGQQPPQHPQNSYHIDPQSQYAQVPPAVTQIQQPQQPPAPHAYMSPQHQQAPPPQGYQPGPNLYGPNGSPAVVNPQSYMSPQQQQQQHPPPHDQFSQLHQQMAAMSMAGGPPVGAPGYHMQNDAVKNNIPIYQQQR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38753-1", "uniprot_id": "HSE1_YEAST", "id": "P38753-1", "name": "Class E vacuolar protein-sorting machinery protein HSE1", "aln": "--MSSSAIKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDANVILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSVHITLKKAVTDVVKQLSDSFKDDPSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMSTQADN-----------SDDEELQKALKMSLFEYEKQKKLQE-QEKESAEVLPQQQQQHQ---QQNQAPAHKIPAQTVVRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIVEPSKE-------------EIEKEKNKEAIVFSQKTT-------------IDQLHNSLNAASKTGNSNEVLQDPHIGDMYGSVTPLRPQVTRMLGKYAKEKEDMLSLRQVLANAERSYNQLMD-------------------------------------------------------------------------------------------RAANAHISPPVPGP-------------------------------------------------ALYAGMTHANNTPVMPPQRQSYQSNEYSPYPSNLPIQHPTNSANNTPQYGYDLGYSVVSQP--------------PPGYEQ------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ***. ::* *:*:** * * .:: : : :*: : .:* :::::* : *.*. :: *:.*::* : . :: :: . * : : . .::.* .: : ::.:. : . . . . :::: **:::** * : . : . *:******: : * :**:* *::: :*:: :**:* : . *:** .:**. :. . : . : . ::.. * . . : :. .: : : * : * . :.: :: .* : :* *: *: . : . : .. : . .* .. : ", "identical_positions": 54, "similar_positions": 133, "identity": "7.81%" }, { "cls_id": "homologset.agr.MGI:1929115", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9F8-1", "uniprot_id": "A0A0G2K9F8_RAT", "id": "A0A0G2K9F8-1", "name": "Zinc finger protein 112", "aln": "MCLVTQEMVTFRDVAVVFSEEELGLLDAAQRKLYREVMLENFRTLLSVAHQPFKPGLIAQLENDEKLWMVAADAQAGGLSGRRSGHTVENAEDTEELNSLCPEELS-CQTWPWG-------QEFIKRCQESTSESWRQGGPPCLLWAGMPVQISEDGNYVLPPVHEDSASIEHPEFPSQRCQQSWEEPHLGRPCN-CLWKGQQTSLRYHFCRCDSIGWSSYHSD-EGLHGKGKSYRFHDHRGETMKASLLNQDLIELGPEPCPCTKYRKSWGHDDSHHSSHTHQQCRSGGKPHTHSPCGEGCGNRSALHGHPDLETGDEGVVRSPPPQSPQRAHMEQVPYKC---SENVHHGSPLNTCGCAHPGNTSQKCSIPEQAVGSCSHRKRTFRAHSGEEPNNHEENGNVLNQSLCLQVNRKISAEEKLCQGAECRKDFTHCSNLNSPHRVHVEETLCNP-DCGNHFSLPPHFQDFPAVRPQGQPHNR-TCCTSFGQTLCLQGHQKLHIREKPFRKEGGNGCNWGSTPKDCE----KQMLHKCSACGKGFSHRRALQVHQRIHTGEKPFKCGECGKGFSRSAYLQAHQRVHTGEKPYKCGECGKGFSRSAYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPYKCEECGKGFSWSFNLQIHQRVHTGEKPYKCGECGKGFSKASTLLAHERIHTGEKPYQCHECGKNFSQKSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTLVKPYNCEVCGKGFSQGSRLEAHRRVHAGGKPYKCETCAKGFSESAGLQAHQRIHAEGRAYKCELCGKGFSGYSGLQAHQRVHTGEKPYKCEVCGKDFSQRSNLQAHQRVHTGEKPYTCDACGKGFRWSSGLLVHQRAHSNDKFCRNGEFRSSYLP-ENLGRNEGL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VAW7-1", "uniprot_id": "ZN112_MOUSE", "id": "Q0VAW7-1", "name": "Zinc finger protein 112", "aln": "-MTKLQEMVTFRDVAVVFSEEELGLLDAAQWKLYREVMLENFRMLLSVAHQPFKPGLIAQLENGEQLWMVEAEAHAGGLSGRRNGHAVENAED-VEVNSLCPEDLSFCQTWPWGACTLPSGQEFIKRCQGSNGESQSQEASPRLVWAGMPMQISEDGNYGLPPAHEDSASMKNQEFPPPRSQQSQGEPYLGRPCVTCQWKGQQTSIRNHFCRYGSVCWSPYHSDNEELYSKGKSYGFHDDRGKTVKVLLLNQDFIELGPEPCPRTKNREAWGHDN-DHSSHTHQQCHSRGKPCTRSLSGEGCGDRSALHGHPGLEAGDEGADGSPPLQSSPRVCMEQVPREC---SGNVHYGSPLNTCGCAHPGNTSQTCSIPKQAVGSPVHCNSTFRAHPREEPNNYEENRNVFNQSSCLQVSRKIGAEEKLCQGVECRKNFTHCSSLNIPHRVPVEETLCNP-DCGNHFSLPPHFQDFPGVRAREQPHNR-LCRTGFSQTLCLQGHQKLHIREKPSHREGGSGCNWSSTPKDPQ----KQKLHKCNACGKGFSHRSVLDIHHRIHTGEK----------------------------PYKCEECGKGFSRSAYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPYKCEECGKGFSWSFNLQIHQRVHTGEKPYKCGECGKGFSKASTLLAHERVHTGEKPYQCHECGKNFSQKSYLQSHQSVHSGERPHICEVCGKGFSQRAYLQGHLRVHTRVKPYKCEVCGKGFSQGSRLEAHQRVHTGRKPFKCETCTKGFSESSRLQAHQRIHEEGRPYKCDQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYTCDACGKGFRWSSGLLIHQRAHSSDTFYRSGECGSSYPP-ENLCRNEGL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJU3-1", "uniprot_id": "ZN112_HUMAN", "id": "Q9UJU3-1", "name": "Zinc finger protein 112", "aln": "-MTKFQEMVTFKDVAVVFTEEELGLLDSVQRKLYRDVMLENFRNLLLVAHQPFKPDLISQLEREEKLLMVETETPRDGCSGRKNQQKMESIQE-VTVSYFSPKELSSRQTWQQSAGGLIRCQDFLKVFQGKNSQLQEQGNSLGQVWAGIPVQISEDKNYIFTHIGNGSNYIKSQGYPSWRAHHSWRKMYLKESHN-YQCRCQQISMKNHFCKCDSVSWLSHHNDKLEVHRK-ENYSCHDCGEDIMKVSLLNQESIQTEEKPYPCTGYRKAFSNDS---SSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIEREDD--IENSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNIYEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTDIEYGKSFICSSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKRYVCSNSFSHNLYLQGHPKIHIGEKP-RKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVHTGEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDKFYKSEDYGKDYPSSENLHRNEDSVLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:******:********:.* ****:******* ** ********.**:***. *:* ** ::: .* ***:. : :*. :: :. :.*::** *** . *:*:* * ...: * . :***:*:***** ** :. :.* :: :*. *.::* : :* .. : ** *:: ***: .*: * .:*.* :: * :.* ** . :*. ****: *: :* * * *:::.:*. **..*** : *** * * .*:**. * ** * .:* *: .. :* *. *: * :* . *.:: ***** *.*: * .* ::*.. . : **.*. :**:::*** **:*** **** :** :**** . * *.* .*.*: *** :**. *. :*** ***..****: *:.: **::* * ..*.:.* **** *:** *** ::* *.* **.*. ** : * :**. *****.** .*::*:*:***** **** ********.:******************************************:****************************** ***************:*:*********.****.***:***************:****************** **** ****:**:*******.******:***:* **:***.*:******: ******:* ***.***: *********.****:****************.********************.***************:***.**.*.* :. : ..* . *** ***. ", "identical_positions": 509, "similar_positions": 187, "identity": "55.15%" }, { "cls_id": "homologset.agr.MGI:1929129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZC08-1", "uniprot_id": "D3ZC08_RAT", "id": "D3ZC08-1", "name": "", "aln": "MN-GFTPEEMSRGGDAAAAVAAVVAAAAAAASAGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88574-1", "uniprot_id": "SAP30_MOUSE", "id": "O88574-1", "name": "Histone deacetylase complex subunit SAP30", "aln": "MN-GFTPEEMSRGGDAAAAVAAVVAAAAAAASAGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75446-1", "uniprot_id": "SAP30_HUMAN", "id": "O75446-1", "name": "Histone deacetylase complex subunit SAP30", "aln": "MN-GFTPDEMSRGGDAAAAVAAVVAAAAAAASAGNGTGAGTGAEVPGAGAVSAAGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYV5-1", "uniprot_id": "SP30L_DANRE", "id": "Q6NYV5-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSHDG-----------------------------------------PP--APPFFGQSCCLIEDAERCGRPAGNASFSKRIQKSISQRKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDD-GGESPDHEVEVPEVDLFQLQVNTLRRYKRHYKIQTRPGLNKAQLAETVSRHFRNIPVNEKETLTYFIYMVKSSKSRLDQKSDSSKQVE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXB3-1", "uniprot_id": "SAP30_DROME", "id": "Q9VXB3-1", "name": "Histone deacetylase complex subunit SAP30 homolog", "aln": "MNNGFSTGEEDSRG------------------------------------------------HTDQTCCLIDDMERCRNQAGYASYSKRIQKTVAQKRLKLSSDPAAQHIYICDHHKERIQSVRTKRRRKDSEDDSNETDTDLHEFP--DLYQLGVSTLRRYKRHFKVQTRQGMKRAQLADTIMKHFKTIPIKEKEIITFFVYMVKMGSNKLDQKNGLGNDTT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **:. * . * .* *** :* *** . ** **:******:::*:::*:. * :.:*:****.**: *****.:*:** *:* ..:: . : * **:** *.********:*: ** *:::***.: : **:.**::**: :* *:* *: ...: * * . . . ", "identical_positions": 77, "similar_positions": 56, "identity": "34.53%" }, { "cls_id": "homologset.agr.MGI:1929183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z136-1", "uniprot_id": "TSC1_RAT", "id": "Q9Z136-1", "name": "Hamartin", "aln": "-MAQLANIGELLSMLDSSTLGVRDDVTTIFKESLNSERGPMLVNTLVDYYLETNSQPVLHILTTLQEPHDKHLLDKMNEYVGKAATRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENVETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKTLETHDVVIECAKISLDPTEASYEDGDA-VSHQLSACFPHRSADVTTSSYVDTQNSYGG-ATSTPSSTSR------LMLFSTPGQLPQSLSSLSTRPLPE--------PLQASLWSPSAVCGMTTPPTSPGNVP-------ADLSHPYSKAFGTTTGGKGTPSG-TPATSPPPAPPCPQDDCAHGPASQASATPPRKEER-ADSSRPYLPRQQDVPSDRGLEDLPGSKGSVTLRNLPDFLGDLAS-----EEDSIEKDKEEAAISKELSEITTAEADPVAPRGGFDSPFYR--DSLSGSQRK------THSAASGTQGFSVNPEP---LHSSLDKHGPDTPKQAFTPIDPPSGSADASPAGDRDRQTSLETSILTPSPCKIPPQRGVSFGSGQLPPYDHLFEVALPKTACHFVSKKTEELLKKAK---------GNPEED----CVPSTSPMEVLDRLLEQGAGAHSKELSR-LSLPSKSVDWTHFGG----------SPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIRAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYSQLQQQRDTMVTQLHSQIRQLQHDREEFYNQSQELQTKLEDCRSMIAELRVELKKANSKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQSKHPDTTKEVEMMKTAYRKELEKNRSHLLQQNQRLDASQRRVLELESLLAKKDHLLLEQKKYLEDVKSQASGQLLAAESRYEAQRKITRVLELEILDLYGRLEKDGRLQKLEEDRAEAAEAAEERLDCCTDGCSDSLLG-HNEEAAGHNGETRTSRPGGTRASCGGRVTGGSSSSSSELSTPEKPPNQR---FSSRWEPTMGEP----SSSIPTTVGSLPSSKSFLGMKTRELFRNKSESQCDEDGMTMS--S-FSETLKTELGKDS------AGMENKTPPSLDAPHPSSP------SSDSMG----------QLHIMDYNETHHEHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP53-1", "uniprot_id": "TSC1_MOUSE", "id": "Q9EP53-1", "name": "Hamartin", "aln": "-MAQLANIGELLSMLDSSTLGVRDDVTAIFKESLNSERGPMLVNTLVDYYLETNSQPVLHILTTLQEPHDKHLLDKINEYVGKAATRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENVETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKTLETHDVVIECAKISLDPTEASYEDGYS-VSHQLSACFPYRSADVTTSPYVDTQNSYGG-STSTPSSSSR------LMLFSPPGQLPQSLSSPSTRLLPE--------PLQASLWSPSAVCGMTTPPTSPGNVP-------ADLSHPYSKAFGTTAGGKGTPSG-TPATSPPPAPPCPQDDCVHGSAAQASATAPRKEER-ADSSRPYLHRQ---SNDRGLEDPPGSKGSVTLRNLPDFLGDLAS-----EEDSIEKDKEEAAISKELSEITTAEADPVVPRGGFDSPFYR--DSLSGSQRK------THSAASGTQGSSVNPEP---LHSSLDKHGPDTPKQAFTPIDPPSGSADVSPAGDRDRQTSLETSILTPSPCKIPPQRGVSFGSGQLPPYDHLFEVALPKTACHFVSKKTEELLKKVK---------GNPEED----CVPSTSPMEVLDRLIEQGAGAHSKELSR-LSLPSKSVDWTHFGG----------SPPSDELRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIRAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYSQLQEQRDTMVTQLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRVELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQSKHPDTTKEVEMMKTAYRKELEKNRSHLLQQNQRLDASQRRVLELESLLAKKDHLLLEQKKYLEDVKSQASGQLLAAESRYEAQRKITRVLELEILDLYGRLEKDGRLRKLEEDRAEAAEAAEERLDCCSDGCTDSLVG-HNEEASGHNGETRTSRPGGTRASCGGRVTGGSSSSSSELSTPEKPPSQR---FSSRWEPALGEP----SSSIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDSVTMSSSS-LSETLKTELGKD-------SGTENKTSLSLDAPHPSSP------NSDNVG----------QLHIMDYNETHPEHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92574-1", "uniprot_id": "TSC1_HUMAN", "id": "Q92574-1", "name": "Hamartin", "aln": "-MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYS-VSHQISARFPHRSADVTTSPYADTQNSYGC-ATSTPYSTSR------LMLLNMPGQLPQTLSSPSTRLITE--------PPQATLWSPSMVCGMTTPPTSPGNVP-------PDLSHPYSKVFGTTAGGKGTPLG-TPATSPPPAPLCHSDDYVHISLPQATVTPPRKEER-MDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLAS-----EEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYR--DSLPGSQRK------THSAASSSQGASVNPEP---LHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAK---------GNTEED----GVPSTSPMEVLDRLIQQGADAHSKELNK-LPLPSKSVDWTHFGG----------SPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVG-HNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEA----SASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSS----LSESLKTELGKD-------LGVEAKIPLNLDGPHPSPP------TPDSVG----------QLHIMDYNETHHEHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEJ0-1", "uniprot_id": "E7FEJ0_DANRE", "id": "E7FEJ0-1", "name": "", "aln": "MSREQLNVGDLLPLLETSDLRQLNEIKGLINEHLNTDRGSVLLNGLVDYFLETNSAQTVHILSSVREPHDKHLFDKMNECMAKAPCRLPTLTLLGHVVRKQPSWIHKIAHYPLLLSLLKCLKTDTDVVVLITGVLVLITLLPMIPQAGKQHLYEFFDIFGRLASWNLRNPGHVPEVYLIHLHASVYSLFHRLYGMYPCNFVSYLRSHYSMKENMDTFEEVVKPMLEHVRIHPELVTGTKDQELDPSRWKRFEIHDIVIECAKVSLDPKEASCEEGYASMPEHFCAHLQQRPADCTASPYGDFHSSYGS-SSSTHFSTPRQPVVPPLALSSISGTQPPYRSPTGTRRQNSSCEFNATYGVKDSLWSPSSQCGMATPPSSRGMSPNPE--LSQSASHLPSRLYSTPAGGKGTPSSSTPAAATP--PPSLSDEYPPVSTPRSTASPPCKDGRPLDHIKPVLVRQEQLRESEKTGPETMNHRDGRGENMPMTLTELSVYMKEQEQLRIEKEREDAAITEELLKLTEEKRDLAGLRG-FDSPFFSTTETLTGAQQKPLPSSILHNTISTPDKTEITPSDKGRVSRGPSQEQPWSFQPVFMPIEHPTHSLLHRSPSAPD-DEALKFGLCSPSPCKPPP-----------MPYEALFDMALPRAASLFVGRKTSEIVQRVAMERFQRGDSGRQGEDEGVEGVASASPLEVLDRLVQQGGDAHDKVLKR-LPLPSKSADWTHFGG----------SAPLDELHTLRSQLLLLHNQLLYERYKREQHAVRNRRLLRRIINATALEEQNNAMKDQLNLQSVDILSLRESLQVEQQRYRQLWDDRETVVTRLHSQIRQLQQARDDYYTKNQELQSKLQECQKRIGEMEAELQKANNEVCHTGHLLNQLTAKLSSSESIQQQLSFLNKQLLLLGEAHKLCVQELHQAGPDTSKEVQMLQTSWGKETERLKQNLLLQSQKLDAAQQRVAELETQLSKKEHLIAEQKKFLEDVKAQAKGELQASESRYQAQRRVTLALQTELLQLYSRLETE---DSSAADSALQAEGVTEP--CITTEPSVIVVGGAIKTATKEDGKPHQSPRGYGSTLSPGHPKASSSPDNSVNGNRDTPPPVLVEPPPHRPHSPLGPPGPLVSSDTPLTVGSYPSAKSFLGMRARELFRNKSESQCDEEETPPPRLTGLSQGLKTELCTETTAKRPSVSTTAQSVTLITSGKESQPDAQRAKKQDTLGSRCPERPRQQPLRIMDYNESRHEHS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BJK9-1", "uniprot_id": "A0A8M2BJK9_DANRE", "id": "A0A8M2BJK9-1", "name": "", "aln": "MAKEQPSVFDLIPLLGSTDLHELEQVKTLLQETLSADKGTMLLNSLVDYFLQTNSSQAVDILSSVREPHDKYLLDKMNECMGKQSCRLSTITLLGHVVRKQPPWIHKIARFPLLVSLLKCLKTDSDVVVLITGVLVLITLMPMIPQTNKQLLCDYFDIFGRLAAWNQRHPGHAQGVFAVHLHASVYSLFHRLYGMYPCNFVSYLRAHYSMKENVDTFEEVVKPMLEHVRIHPELITGTKDYEVDPIRWKRFEPHDIVIECAKISLDSKEASSEEGYSSLADHIQRRAVHHSQSCSELSFHEISSVTPIGAICQSLSKSQ----PYLTVTQDSGSSAQTPNNQSDEVKSS--------GMKEELWSPSSICGMSTPPSSRGMSPTTVSDISLSASHLSGRIPSTPGDGKWTLSPSTPSGSSP--LPSLSEEIG--QAAQNTSSTQAKTCKEVKKFT-----------SRSINNSSENGGDAKTPVSLAQLSDIVK--------RTEGEREDDTINEEILSLTHGKLD-FGSRPGLESSFSGSLDTLLSSHPN-----HEQNLVSTPDRVECSAKAG-------EQQLPRSLWP-FTPIE--NGKHSKCSLSDLTKES---------------------------MPYEPLFDLALPKVASLFLERKTAEAFRRVEGE-------RDHQDEMEGEDLSVTSPLEVLDRVIQQGHDTHGKVLKRTFSSPSQSSDPHLKGKQHSNKGKGLVPAVSDELDMLRSQLLLLHNQLLYERHKREQHALRNRRLFGRIVNTTALEEQNNSMKTQLKLQEVEIQAVKVSLKEEQRRSVHIQEDREAVVNQLQTQIQQLQKERNDYYSKMQVLKSELQENQTKAGKMEAELQKANNKVCNMGHMLSQLSIKLNNSENMEQQMAFLNKQLLLLGEANKLYMEEIDRLGPEAHKELNMLQASSVREGERLRQSSLQQSQRLEAAQQRITDLENQLTKKEQVIREQKKLLDNVKRQATEQLQASENRYLAQKNITQALQTELLELYSKIELKN------LKTNAPAEPISDPSSPTNQRPNGNSAG----PSAPSLPADLMKREEGAHVCVNGEISAASPQTPTALINGSQEEDLS-----ALTHSFPSLP------CQPFAVGSYPSTRSFLGKKAREMFRNKSESHYDGDSPTLT---CLSKDLKGEPITDP----TESLESEEAADQFDLQPMDRP------RAYNVQSR-----RHQDLRIMDYNETHHVH-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :*:.:* :. * :::. :::* *.:::*.:*:* ****:*:*.* .:.**::::*****:*:*::** :.* . **. ::*****:* **.* **::: *** ******* *:***** ********::*****:.** * ::*******::* ::***. *: :*******:***************:**:*******::*********:*********:**:** *:** *** :* **:******:***..*** *:* : :..:: :. . : .: : . : . *..: * : . .* . . . . . : ***** ***:***:* * * . ** .: .*. .** * **: :.* . .:: .: : :. * : . .. . . . * :: * ::*: :*..*: .:* : : * ::*.* ::* .:: : :. * .: . ... .: * : * **: . . . : **: **::***:.* *: :** * .::. :: :. :**:*****:::** .:*.* *.: :. **:* * * .. **: **.*************.**:***:*****: :::.::****:* :** **:**. :* : **: ** * :: ::*:::*.:*::**:***: *:::*.: * *:::*:: :. .::. **:***.:**: :*.*:: **..**.::**: ***:***:***.::* ::::. .:: **::*:::: :* *: :. * *.*:*:::*:*: :**. *:**:::: **** *::** ** :* *:*.** **:.:* .:: *:*:**.::* . . ** : . . * :: .. ..*. : . . .. . . * :*** **::**** ::**:*******: * : . . :*: ** * .: : : . * .: *:******:: * ", "identical_positions": 388, "similar_positions": 356, "identity": "30.74%" }, { "cls_id": "homologset.agr.MGI:1929185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQF4-1", "uniprot_id": "JUNO_MOUSE", "id": "Q9EQF4-1", "name": "Sperm-egg fusion protein Juno", "aln": "MAQWWQILLGLWAVLPTLAGDKLLSVCMNSKRHKQEPGPEDELYQECRPWEDNACCTRSTSWEAHLEEPLLFNFSMMHCGLLTPACRKHFIQAICFHECSPNLGPWIQPV-------VPNGQEEQRVWGVPLCQEDCEDWWRACHSSLTCKSNWLHGWDWSEEKKHCPAHEPCLPFSYHFPTPDDLCEKIWNNTFKASPERRNSGRCLQKWFEPTLSNPNVEVALHFAGSALAPQLSYTLPAFSLCLLFHP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M928-1", "uniprot_id": "JUNO_RAT", "id": "F1M928-1", "name": "Sperm-egg fusion protein Juno", "aln": "MAQWWLILLGLWTVLPSLAGGKLLNVCMNSKHHKQEPGPEDKLYFECMPWKDNACCTRDTSWEAHLDEPLLFNFSMTHCGLLTPLCHKHFIQAICFYECSPNLGPWIQPV-------VPNRQEEQRLWDVPLCLEDCEEWWKDCRTSHTCKADWLHGWVWDQGKNGCPAHAPCLPFSDYFPTPADLCEKIWNNTFKASPERRNSGRCLQKWFEPTHGNPNVEVALHFAGSASAPQLSYSITAFSLCLLLHA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6ND01-1", "uniprot_id": "JUNO_HUMAN", "id": "A6ND01-1", "name": "Sperm-egg fusion protein Juno", "aln": "MACWWPLLLELWTVMPTWAGDELLNICMNAKHHKRVPSPEDKLYEECIPWKDNACCTLTTSWEAHLDVSPLYNFSLFHCGLLMPGCRKHFIQAICFYECSPNLGPWIQPVGSLGWEVAPSGQGE-RVVNVPLCQEDCEEWWEDCRMSYTCKSNWRGGWDWSQGKNRCPKGAQCLPFSHYFPTPADLCEKTWSNSFKASPERRNSGRCLQKWFEPAQGNPNVAVARLFASSAPSWELSYTIMVCSLFLPFLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** :** **:*:*: **.:**.:***:*:**: *.***:** ** **:****** *******: . *:***: ***** * *:*********:************* .*. * * *: .**** ****:**. *: * ***::* ** *.: *: ** ***** :**** ***** *.*:********************: .**** ** **.** : :***:: . ** * : .", "identical_positions": 154, "similar_positions": 45, "identity": "61.35%" }, { "cls_id": "homologset.agr.MGI:1929209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56857-1", "uniprot_id": "CLD18_MOUSE", "id": "P56857-1", "name": "Claudin-18", "aln": "MATTTCQVVGLLLSLLGLAGCIAATGMDMWSTQD-LYDNP--VTAVFQYEGLWRSCVQQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGG------MGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56856-1", "uniprot_id": "CLD18_HUMAN", "id": "P56856-1", "name": "Claudin-18", "aln": "MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQD-LYDNP--VTSVFQYEGLWRSCVRQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMG---------GMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDEVQSYPSKHDYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40EBY6-1", "uniprot_id": "A0AB40EBY6_DANRE", "id": "A0AB40EBY6-1", "name": "Claudin", "aln": "MSAPALQTTGFVSGVIGTAGVFAATLMDVWCFRNQQQDQPQRVSSIYTYKGLWKDCEMSGTVFPECQPLYSHPNYSGILQAARALMIIAILVAVIAVFIGFFCLKCLKMKNMQLSTRAKLILSSAIIFFIAGICGIAAASVYADQLVPSFMMPQFNQKQGEKGGVQCANNVAAMDPSASRYTFGPALYIAWVGAALLILGGILMSIAYKRMQW------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::.: *...:: .::* ** :*** **:*. :: *:* *:::: *:***:.* ..: *.**:* :: . ..:***.*****:.*::..*.:::.:*.***::: .*: *::*:: *:*.*:*:::*:*.* ..**:*: **..* *. * * . ::. :*****.**::.**...* ::**::*.** : : ", "identical_positions": 71, "similar_positions": 93, "identity": "26.01%" }, { "cls_id": "homologset.agr.MGI:1929211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQE0-1", "uniprot_id": "RN138_MOUSE", "id": "Q9CQE0-1", "name": "E3 ubiquitin-protein ligase RNF138", "aln": "MSEELSAATSYTEDDFYCPVCQEVLKTPVRTAACQHVFCRKCFLTAMRESGIHCPLCRGSVTRRERACPERALDLENIMRRFSGSCRCCSKKIKFYRMRHHYKSCKKYQDEYGVSSVIPNFKISQDSVRSSNRSETSASDNTETYQEDTSSSGHPTFKCPLCQESNFTRQRLLDHCNSNHLFQIVPVTCPICVSLPWGDPSQITRNFVSHLNQRHQFDYGEFVNLQLDEETQYQTAVEESFQVNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99PD2-1", "uniprot_id": "RN138_RAT", "id": "Q99PD2-1", "name": "E3 ubiquitin-protein ligase RNF138", "aln": "MSEELSADTSYTEDDFYCPVCQEVLKTPVRTAACQHVFCRKCFLTAMRESGIHCPLCRGSVTRRERACPERAIDLENIMRRVSGSCRCCSKKIKFYRMRHHYKSCKKYQDEYGVSSVIPNVKISQDSVRSSNRSETSASDNTETYQEDTSSSGHPTFKCPLCQESNFTRQRLLDHCNSNHLFQIVP------------------------------------VNLQLDEETQYQTAVEESFQVNM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WVD3-1", "uniprot_id": "RN138_HUMAN", "id": "Q8WVD3-1", "name": "E3 ubiquitin-protein ligase RNF138", "aln": "MAEDLSAATSYTEDDFYCPVCQEVLKTPVRTTACQHVFCRKCFLTAMRESGAHCPLCRGNVTRRERACPERALDLENIMRKFSGSCRCCAKQIKFYRMRHHYKSCKKYQDEYGVSSIIPNFQISQDSVGNSNRSETSTSDNTETYQENTSSSGHPTFKCPLCQESNFTRQRLLDHCNSNHLFQIVPVTCPICVSLPWGDPSQITRNFVSHLNQRHQFDYGEFVNLQLDEETQYQTAVEESFQVNI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*** ***********************:******************* *******.************:*******:.*******:*:************************:***.:****** .*******:*********:************************************** **********************:", "identical_positions": 190, "similar_positions": 16, "identity": "77.55%" }, { "cls_id": "homologset.agr.MGI:1929212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKC8-1", "uniprot_id": "AP3M1_MOUSE", "id": "Q9JKC8-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVENVPP-VISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPT--------GQLSN-----------IPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFK-------ENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMN----------LTPTQGSYTFDPVTKVLAWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPNLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYVTKAGKFQVRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53676-1", "uniprot_id": "AP3M1_RAT", "id": "P53676-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVENVPT-VISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPT--------GQLSN-----------IPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHNISFK-------ENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMN----------LTPTQGSYTFDPVTKVLAWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPNLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYITKAGKFQVRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2T2-1", "uniprot_id": "AP3M1_HUMAN", "id": "Q9Y2T2-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVENVPP-VISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPT--------GQLSN-----------IPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFK-------ENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMN----------LTPTQGSYTFDPVTKVLTWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPSLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYVTKAGKFQVRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76928-1", "uniprot_id": "O76928_DROME", "id": "O76928-1", "name": "", "aln": "MIHSLFIVNSGGEVFLEKHWRSVVS---------RSVCEYFLDAQRAAP--YDVPP-VIATPHYYLITVQRDTVSLVAACKQEVPPLFVIEFLHRVVDTFQDYFG--DCSESVIKDNYVVVYELLDEMLDNGFPLATES---NILKELIKPPNILRTIANTVTGKSNVSTTLPS--------GQLSA-----------VRWRRS-GVRYTNNEAYFDVIEEVDAIIDKSGS---TVFAEIQGHIDCCIKLSGMPDLTLSFMNP-RLFDDVSFHPCVRYKR-WEAERLLSFIPPDGNFRLMSYHISSQSVVAIPIYIRHNFSIK-------TGE-QGRLDLTIGPRNTLGRTVDKVKLELTMPRCVLNCL----------LTPNQGKYTFDSVTKTLSWDVGRIDVS-KLPNIRGSVSITPGTT---NIDANPSVNVQFQISQLAVSGLKVNRLDMYG-----EKYKPFKGVKYLTKAGKFQVRM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38153-1", "uniprot_id": "AP3M_YEAST", "id": "P38153-1", "name": "AP-3 complex subunit mu", "aln": "MYLSFYITDTKNKLIFQYLLGATAPSFKHLWTRVQSTCPQLLEDSSSDDYLDHSMVGRDLEVYKYFSVINKLNYWCLASTSKSKGPLDCFTFLETIDRILLEYFDKDKLSIKKIVNNYDRISLIFNCCVEAGEPNVSDMLYVNKIKEAVPERSDLSKFISSTAHNLQQAVQLPQQRQQQLQQNQISRGSNSLIENEEIVPWRTSRASKHENNELYVDLLETFHVVFEKKKSHLRLLTGSIHGIVDVRSYLNDNPLVAVKLNTMGNDIGIPSLHDCVEINDGVFSPSNITFIPPDGKFRLLEYSVDLSSQVKQSGVRMNSIGLMSLHFQNGLGKDSDEFELSLN-IENFKKVSQVDDLKIDLQFNVENADPNEIAYKIKILRNTHGRFENSIIMGQGQWIFDKSTATGTVPVLRGCIEYENTGPNFTKKVDLQTVSLEYSYIGQSASGIYVEAIDIVSGLTIGKNTKLYKGAKYKTQTGNFQVRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::: : ..:::: :... :*.* ::: . . : *: : : . :: . . ** : **. : : :**. . * * :* : ::: :: * * .:: * :** : . * .. .: : . : . ** .*:* : ** : . :: *** *.*::* ...:::*. * : ..*:* :* *.. * :::.: . . :. *:* *:. : : ::******:***:.* :. .. * . :.:.: .. ..:::::. :.: :. : : : : * * * .:* : . : * ..: .:* ::* :. . : .:.:::. : **: *: :*: . :: * :**.** *::*:**** ", "identical_positions": 75, "similar_positions": 166, "identity": "15.5%" }, { "cls_id": "homologset.agr.MGI:1929213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1W2Q6H7-1", "uniprot_id": "A0A1W2Q6H7_RAT", "id": "A0A1W2Q6H7-1", "name": "Zinc finger and BTB domain-containing protein 20", "aln": "MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPG-----IQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGS-GERSFYSG-AVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGAGATREGQVEAAQPEQAAEAPAESSAQPNQLETGASSPERSTEVEMDNTVITVSNSSDKGVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLTGQQTQFVTVSQPGLSTFTAQLPAPQPLASSASHSTASGQGDKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASN------GTPPAGTPPG-----------------------------------ARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0L9-1", "uniprot_id": "ZBT20_MOUSE", "id": "Q8K0L9-1", "name": "Zinc finger and BTB domain-containing protein 20", "aln": "MLERKKPKTAENQKASEENEITQPGGSSAKPALPCLNFEAVLSPAPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPG-----IQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGS-GERSFYSG-AVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGAAAPRDGQAEPAQPEQAAEAPAESSAQPNQLEPGASSPERSNESEMDNTVITVSNSSDKGVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLTGQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGDKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASN------GTPPAGTPPG-----------------------------------ARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC78-1", "uniprot_id": "ZBT20_HUMAN", "id": "Q9HC78-1", "name": "Zinc finger and BTB domain-containing protein 20", "aln": "MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPG-----IQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGS-GERSFYSG-AVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASN------GTPPAGTPPG-----------------------------------ARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TVP4-1", "uniprot_id": "A0AB32TVP4_DANRE", "id": "A0AB32TVP4-1", "name": "Zinc finger and BTB domain-containing protein 20", "aln": "-------------------------------------------------------------------------MTERIHHINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGISGSGSFSVVPGDSGQETPRGTPESGTSGPSSDAESGYMQTSHQSVYSSLYSSCSGLGLQNGTRGNRSHYAGAAVIANYDSALPLQQKEAGQDPAWITRIHERSQQMERFLSTT-ETTHCRKQPRPVRLHP--GDIHIKQEQGDEFNCYG-----------IEDCREDGEPLECVESEPKGESFDSGVSSSIGTETDSVEQPFLSGFNCPSKGQQGE-----------RGTPVQIEVNDSSPEQTQEIIEDSSGNGPTQES--GEIGIHQANLTAPQVMPG-GPYLRPGEPLTSNLRMPLTLTSNSQVMGTAGNTYLPTLFATQSASDN-KPFLFSLPQSIGSQQPQFVAVPSPNMPPFPGGLSVPPGGSQQQGGAPGGQHGEKKPYACTLCCKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHMALHSTGSGVSGVSGVSGAGSAGGPASIPVPMAVPEPGAGVVALAMPVGGGVAGGGVGNAGVGVAAEASCQEGTTYMCSVCPVKFDQIEHFNDHMRKHVSDG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****** ********************************************************************************************************************** .* ****:************ ***:****:*: * . :**: . .:***: *:**.*:* **::::::** * :.. :**:**************:**** *************::. *:****** *::: ** *:* ** : * .********************.***** * .. .: : : . *:* . ****:: * *.: ::.* . : ..* : * :*. *** *.**************:**:*********:**:**.*... *********.: .**.***:*..*.:..*.. *..* :.. . :... :*:**** **** ************************************************************************************************:****:.. *.. **:. * * .* .. .:* *****:*****.******:****** *****", "identical_positions": 447, "similar_positions": 111, "identity": "56.65%" }, { "cls_id": "homologset.agr.MGI:1929214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53678-1", "uniprot_id": "AP3M2_RAT", "id": "P53678-1", "name": "AP-3 complex subunit mu-2", "aln": "MIHSLFLINSAGDIFLEKHWKSVVS---------RSVCDYFFEAQERATEAEN-VPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFG--VCSEPVIKDNVVVVYEVLEEMLDNGFPLATES---NILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLS-------------------VVPWRRT-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVTAEIQGVIDACVKLTGMPDLTLSFMNP-RLLDDVSFHPCVRFKR-WESERILSFIPPDGNFRLLSYHVSAQNLVAIP---VYVKHSISFRDSGSLGR----FEITVGPK-QTMGKTIEGVTVTSQMPKGVLN--------MSLTPSQGTHTFDPVTKMLSWDVGKINPQ-KLPSLKGTMGLQVG---ASKPDENPTINLQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGIKYMTKAGKFQVRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2R9-1", "uniprot_id": "AP3M2_MOUSE", "id": "Q8R2R9-1", "name": "AP-3 complex subunit mu-2", "aln": "MIHSLFLINSSGDIFLEKHWKSVVS---------RSVCDYFFEAQERATEAEN-VPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFG--VCSEPVIKDNVVVVYEVLEEMLDNGFPLATES---NILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLS-------------------VVPWRRT-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVTAEIQGVIDACVKLTGMPDLTLSFMNP-RLLDDVSFHPCVRFKR-WESERILSFIPPDGNFRLLAYHVSAQNLVAIP---VYVKHSISFRDSSSLGR----FEITVGPK-QTMGKTIEGVIVTSQMPKGVLN--------MSLTPSQGTHTFDPVTKMLSWDVGKINPQ-KLPSLKGTMGLQVG---ASKPDENPTINLQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGIKYMTKAGKFQVRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53677-1", "uniprot_id": "AP3M2_HUMAN", "id": "P53677-1", "name": "AP-3 complex subunit mu-2", "aln": "MIHSLFLINSSGDIFLEKHWKSVVS---------RSVCDYFFEAQERATEAEN-VPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFG--VCSEPVIKDNVVVVYEVLEEMLDNGFPLATES---NILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLS-------------------VVPWRRT-GVKYTNNEAYFDVIEEIDAIIDKSGS---TITAEIQGVIDACVKLTGMPDLTLSFMNP-RLLDDVSFHPCVRFKR-WESERILSFIPPDGNFRLLSYHVSAQNLVAIP---VYVKHNISFRDSSSLGR----FEITVGPK-QTMGKTIEGVTVTSQMPKGVLN--------MSLTPSQGTHTFDPVTKMLSWDVGKINPQ-KLPSLKGTMSLQAG---ASKPDENPTINLQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGIKYMTKAGKFQVRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76928-1", "uniprot_id": "O76928_DROME", "id": "O76928-1", "name": "", "aln": "MIHSLFIVNSGGEVFLEKHWRSVVS---------RSVCEYFLDAQR--AAPYD-VPPVIATPHYYLITVQRDTVSLVAACKQEVPPLFVIEFLHRVVDTFQDYFG--DCSESVIKDNYVVVYELLDEMLDNGFPLATES---NILKELIKPPNILRTIANTVTGKSNVSTTLPSGQLS-------------------AVRWRRS-GVRYTNNEAYFDVIEEVDAIIDKSGS---TVFAEIQGHIDCCIKLSGMPDLTLSFMNP-RLFDDVSFHPCVRYKR-WEAERLLSFIPPDGNFRLMSYHISSQSVVAIP---IYIRHNFSIK-TGEQGR----LDLTIGPR-NTLGRTVDKVKLELTMPRCVLN--------CLLTPNQGKYTFDSVTKTLSWDVGRIDVS-KLPNIRGSVSITPG---TTNIDANPSVNVQFQISQLAVSGLKVNRLDMYG-----EKYKPFKGVKYLTKAGKFQVRM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38153-1", "uniprot_id": "AP3M_YEAST", "id": "P38153-1", "name": "AP-3 complex subunit mu", "aln": "MYLSFYITDTKNKLIFQYLLGATAPSFKHLWTRVQSTCPQLLEDSSSDDYLDHSMVGRDLEVYKYFSVINKLNYWCLASTSKSKGPLDCFTFLETIDRILLEYFDKDKLSIKKIVNNYDRISLIFNCCVEAGEPNVSDMLYVNKIKEAVPERSDLSKFISSTAHNLQQAVQLPQQRQQQLQQNQISRGSNSLIENEEIVPWRTSRASKHENNELYVDLLETFHVVFEKKKSHLRLLTGSIHGIVDVRSYLNDNPLVAVKLNTMGNDIGIPSLHDCVEINDGVFSPSNITFIPPDGKFRLLEYSVDLSSQVKQSGVRMNSIGLMSLHFQNGLGKDSDEFELSLNIENFKKVSQVDDLKIDLQFNVENADPNEIAYKIKILRNTHGRFENSIIMGQGQWIFDKSTATGTVPVLRGCIEYENTGPNFTKKVDLQTVSLEYSYIGQSASGIYVEAIDIVSGLTIGKNTKLYKGAKYKTQTGNFQVRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::: :: ..:::: :... :*.* ::: . . : : *: : : . :* . . ** : **. : : :**. * * :* : ::: :: * * .:: * :** : . * .. .: : . : . ** : . * ** : . :: *** *.*::* ...:::*. * : ..*:* :* *.. * :::.: . . :. *:* **. : : ::******:***: * :. .. * . : :*:: . *: :::::. . . :: : : : : * .:* . . : .* ..: .:* ::* : :: ::.:::. : **: *: :*: . :: * :** ** *::*:**** ", "identical_positions": 76, "similar_positions": 158, "identity": "15.73%" }, { "cls_id": "homologset.agr.MGI:1929215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQ35-1", "uniprot_id": "A0A8I6AQ35_RAT", "id": "A0A8I6AQ35-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETESLEESTDESEEE-SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDESGEHMGVCSEDGKLQVFGLYSGEEFHET-FDCPIKIVAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKIFDITSKQRITNVPRDD-----ISLRPDMYPCSLCWKDAVTLIIGWGTSIKICSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISHRNIKRHKILEIGLAYVNHLVERGEYDMAARKCQKILGKNA---------------SLWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSLNAPAQYCNICSAKNRGPGSAILEMKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5KU39-1", "uniprot_id": "VPS41_MOUSE", "id": "Q5KU39-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETESLEESTDESEEE-SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDDSGEHMGVCSEDGKLQVFGLYSGEEFHET-FDCPIKIIAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKVFDITSKQRISNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSIKICSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQRNIKRHKILDIGLAYVNHLVERGEYDMAARKCQKILGKNA---------------SLWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSMNAPAQYCNICSAKNRGPGSAILEMKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49754-1", "uniprot_id": "VPS41_HUMAN", "id": "P49754-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHET-FDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNA---------------ALWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F590-1", "uniprot_id": "VPS41_DANRE", "id": "E7F590-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEVEEQGRKLSEESTDESEEEDTEEEPKLKYERLTNGVTEILQKDAASCMTVHDKFLALGTHFGKVFLLDIQGN-VTQKFEISS-----VKINQISLDESGDHVGICSEDGKVQVFGLYTREGFHEN-FDCPIKVVALHPQFSKSNNKQFVTGGNKLLLYERNWLNRWKTSVLHE--------------GEGNITSVKWRGNLIAWANNVGVKIYDIGSKQRITNVLRDN-----TSLRPDMYPCSLCWKDNTTLIIGWGCSVKICAVKERD-------------------------------PTEMR--DLPSRYVEIVSAFETEFFISGLAPL-ADQLVTLYYVKENSDHMEEEFRTRPRLDIIQPLPE----------------GCEEISSDALTVRNFQENQCRDYRLEHSEGESL--FYIISPKDIVVAKERDQDDHIDWLLEKKKYEEALMAAEISFKNIKRHDVQKIGMAYINHLVEKGDYDTAARKCQKVLGKNM---------------DLWENEVYRFKTIGQLKAISQYLPRGDL-RLRPAIYEMILHDFLKTDYEG-FATLIREWPGELYNNMAIVQAVN----------EHLKKDPTNSILLTTLAELYTYDQRYDRALEIYLRLRHKDVYQLIHKHNLFSSIKDKIVLLMDFDKE-------------------KAVDMLLDNEDKISMDKVVEELKDRP-----ELLHVYLHKLFK-RDHHKGQKYHERQISLYAEFDRPNLLPFLRESMHCPLEKALEICQQRH-FVEETVFLLSRMG--NCRRALQMIMEELANVDKAIEFAKEQDDRELWEDLISYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILHDYNLQILLREGCKKILVADSLSLLQRMHRTQKKGVRVDEENICESCHTPILPSDTAQAFGVVVFHCRHMFHKECLPSPGSIPGIQYCNICSAKRRGPGSGILEMKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PL76-1", "uniprot_id": "VPS41_DROME", "id": "Q7PL76-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAKALP--LISCDSWADSINEE--DVEPKFKYHRLANDLKYMLNADVITCSAVHLKFLIFGTFRGRVCIFDHQGNSVYSNLSASERHTHQVAVNNIDVDHKGEYVATCSDDGKVNITGLFSSDNNHSLSFGKFIKVVSLEPDS-KAHIKRFVVGDDKLILYERNLLKKLKPVELCS--------------VEGSVLSICWHGNFIAWASHIGVRVYDLNERCSLGLIKWEVP----PQERLENFRCHLRWSNKHTLLIGWVDTIRVCVIRKRN-------------------------------SIEASTGNLPVYIVDPISTFQTTFYVCGLAPLSAKQLVVLGFRKEKSSCFK---ALRPVLCVIEYKMN----------------NSEEICTDSLTLRGFEEYTVNDYSLGGIIEENR--FYIVAPKDIVVASLIETDDRIEWLIKHSKFEEAMELISANGGNVP---VLSVAKLYINHLLALKKYDDAAKLCLRMLGNDK---------------VLWEEEVFKFVKCQQLRSVSAYLPTSDECKLDPHVYEMVLYEFLKFDVCG-FLNLIKEWPSHLYDGLAVINAIH----------DNFRKHYAN-QLLESLALLYSYQGDFESALRMYLKLQNKDVFQLIRRYELYDVISKLIIPLIQLDRD-------------------CAFEILLDKK-KIKTEIVVHQLEHNQ-----EYLYWYLDSLLK-KDPSN--VFQKKLISLYAIFDRNKLLPFLKRSKDYDIQEALVICKQEN-FYPEIVYLLGCMGGVEASEALNIIIHRIRDIEMAIEFCKEHDDSDLWNALINEFSKHPEIVTKVLDGIVDYFSPAVVVGK-IKMGQNIPNLRQSLIKMLRHYNLQGEILSSAQQIQLNDYFEIHSEIVTTQRRGQQVSYEQLCSLCHRPVLMAG-THLYCIIRLECGHVYHKPCIQG----ELLKNCNECNLWKLTVGK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38959-1", "uniprot_id": "VPS41_YEAST", "id": "P38959-1", "name": "Vacuolar protein sorting-associated protein 41", "aln": "MTTDNHQNDSVLDQQSGERTIDESNSISDENNVDNKREDVNVTSPTKSVSCISQAENGVASRTDESTITGSATDAETGDDDDDDDDDDDEDEDDEDEPPLLKYTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHLTTCAFEPIKTIKCHRS--------SILCINTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNFQASRMFVSGGMAGDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILWMDDDGITFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLFKVSFTKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVSMLITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDLFNGDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFDWFMERKQYYKAWKIGKYVIGSEER---FSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLNSLDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKKPA--LRKSVYDDVLHYFLANDMINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYLKENKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIFEIQTIFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMISPYENQLIELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIG--ETKKALSLIIDELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYLKVIRGMSDDLQIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQGKLFQVDESDIEINDDLNGVL----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :. *. :*: : * :** *::: . ::: * :. . .*: :**. * : : : : . : :: .*.:.. * **.: : .: : . * *: :::... : .::* :*. : . * . :* : .: *.:* * .. *: . *: : : : . * : : : : : ::*** .: : : . . . * *: . * . : : ***.: .**: * : : .. : . : : :** .* : ::.::: .** * :. :*:::..* : .. . .*:::*::::.:: :* . . .:. ::* *: .:. . :: : * : : :: :: :* * :*: :*: ** * . * * :* .*:. . : :. ::. * *. ** : : *: * :. . :*: :* . *: :: : . ..::*:::. .*. : . ::. : . ** .::. * :.:: *.**: :** .*****: . ::.*: :*... : * ::* . :* : **.:*:..: : : **:* *: .* :**: :* .:* : . :* . : : : :. . :* **:: : ::::. .*. : .. * : .: ..: : :* .. :: : ", "identical_positions": 112, "similar_positions": 292, "identity": "10.58%" }, { "cls_id": "homologset.agr.MGI:1929230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6R9-1", "uniprot_id": "G3V6R9_RAT", "id": "G3V6R9-1", "name": "", "aln": "MEEGPAIGTLSREVSTEEAEPLVAAWSGDSGHVSQSHSSASGPWEDDGTED-APGRDLPLLRRAALGYASSLLPATGPRPEVEALDASLEDLLAKVDEFVGMLDMIRGDSSHVVSEGVPRIHAKAAEMRRIYGRIDKLEAFVRMIGSSVARMEEQVTKAEAELGTFPRAFRRLLHTISVPALF----KSAPTAPQ----RAVYEPPVLFRTEDHFPGSGDRPQL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VED2-1", "uniprot_id": "BL1S4_MOUSE", "id": "Q8VED2-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 4", "aln": "MEEGPAVGTLSREVSTEEAEPLGAAWSGDSGHVSQSHSSASGPWDDDGPED-APGRDLPLLRRAASGYASSLLPSAGPRPEVEALDASLEELLAKVDEFVGMLDMIRGDSSHVVGEGVPRIHAKAAEMRRIYGRIDKLEAFVRMIGSSVARMEEQVAKAEAELGTFPRAFRRLLHTISVPALF----RSAPSGPQ----RAAYEPPVLFRTEDHFPGCGDRPQL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUP1-1", "uniprot_id": "BL1S4_HUMAN", "id": "Q9NUP1-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 4", "aln": "MEGSFSDGGALPEGLAEEAEPQGAAWSGDSGTVSQSHSSASGPWEDEGAEDGAPGRDLPLLRRAAAGYAACLLPGAGARPEVEALDASLEDLLTRVDEFVGMLDMLRGDSSHVVSEGVPRIHAKAAEMRRIYSRIDRLEAFVRMVGGRVARMEEQVTKAEAELGTFPRAFKKLLHTMNVPSLFS---KSAPSRPQ----QAGYEAPVLFRTEDYFPCCSERPQL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTC2-1", "uniprot_id": "BL1S4_DROME", "id": "Q9VTC2-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 4", "aln": "---------------------------------MQSN-----------------------IENVSRDYAK-ILQSADLEKEINPLCTNIEDMLARLDEFETLLASVRAESNGMMANNVCSILGFTDSFEQLKARIDGLEQCVGVVSANLSEVERSVDIAEEELHVTDYSLKGLLLKPLKAKLSASDTSTLSSLPRSNLVEEEYQPVEIYKSDDYFGKSEEENYVAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :...: .** :* .:. . *::.* :.:*::*:::*** :* :*.:*. ::.:.* * . : .:.:: .*** ** * ::.. ::.:*..* ** ** . ::: ** . . * : .: *: . *:. :::::*:* . :. : ", "identical_positions": 36, "similar_positions": 74, "identity": "15.93%" }, { "cls_id": "homologset.agr.MGI:1929237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU56-1", "uniprot_id": "PUS1_MOUSE", "id": "Q9WU56-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "---------MGFPRLWAALLRNWGRWTARPGPRVPGLPPMAGNKVPPALAS-HQP-DRK-----GRGG--WVWEET-EHPAKRVKGGEDEE---PPRKLPKRKIVLLMAYSGKGYHGMQRNLGSSQFRTIEDDLVSALVQAGCIPENHGTDMRKMSFQRCARTDKGVSAAGQVVSLK-VWLIDDILDKINSHLPSHIRILGLKRVTGGFNSKNKCDARTYCYMLPTFAFAHKDRD--------------------------------------------------------------------------VQD--ESYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPREPSARRYILEMYCEEP-FVR-EGLEFAVIKVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGE-EKVDVPKAPGLGLVLERVHFEKYNQRFGGDGLHEPLDWTQEEGKVTAFKEQYIYPTIVSTERDERSMAQWLNTLPIHNFSGTALGAADTGAKVPSSLEGSEGDGDTD---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KM92-1", "uniprot_id": "PUS1_RAT", "id": "Q4KM92-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "---------MGFPRLWAALLRAWGRWTARPGPRVPGLPPMAGNKVPPALPS-HQP-DRK-----GRGG--WVWEET-EHPAKRVKGGEDEE---PPRKLPKRKIVLLMAYSGKGYHGMQRNLGSSQFRTIEDDLVSALVQAGCIPENHGTDMRKMSFQRCARTDKGVSAAGQVVSLK-VWLIDDILDKINSHLPSHIRILGLKRVTGGFNSKNKCDARTYCYMLPTFAFAHKDRD--------------------------------------------------------------------------VQD--ESYRLSAETLQQVNRLLGCYKGTHNFHNFTSQKGPREPSARRYILEMYCEEP-FVR-EGLEFAVIKVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGE-EKVDVPKAPGLGLVLERVHFEKYNQRFGSDGLHEPLDWAQEEGKVTAFKEQYIYPTIVSTERDERSMAQWLNTLPIHNFSGTALGADDTGAKVPSSLEGSEGDGDTD---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y606-1", "uniprot_id": "PUS1_HUMAN", "id": "Q9Y606-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "---------MGLQ--LRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGA-ACPQDRRSC--SGRAGGDRVWEDG-EHPAKKLKSGGDEE---RREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLK-VWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRD--------------------------------------------------------------------------VQD--ETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEP-FVR-EGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGT-EKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QWW1-1", "uniprot_id": "F1QWW1_DANRE", "id": "F1QWW1-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "-----------------MLKSSCRIINSVLSQHLLQFSKLKGDQTRVFCSSFNMTEDSVKA--VKRAADDDPHTET-EHEDKKLKTDQEE------RKYPKKKVALLMAYSGKGYYGMQRNARNSQFKTIEDELVTALVGARCIPEGHAEEMKKMSFQRSARTDKGVSAVGQVVSLK-VWMIENILEKINAHLPPQIRVLGCKRVTGGFNSKNNCYARTYSYMLPTVAFSPKDYN--------------------------------------------------------------------------QED--TSFRLTSDTLQTVNRLFGLYKGTHNFHNFTSQKGHRDPSAMRYITHMSCGEP-FIR-KDVEFAVITVRGQSFMMHQIRKMIGLVIAVVKGYVDEGVIEKSWGE-EKVGVPKAPGLGLVLERVHFDGYNKRFGGDGIHETLEWTEQEEAIADFKEKHIYPTIVDTELNEKSMVNWMTSLCIHDFEETATGNQDR-------KDDDEDGNASD---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIR1-1", "uniprot_id": "E1JIR1_DROME", "id": "E1JIR1-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "MFLRRLLNDYTKAVRLKTLCNPWNRHKSFAAAMSEALDKLEVEKEARKEAKELEGEAVKDANRIKRTLKRKKWVDWKEQDEKDAANGVKRAPFDPADRIKRKKSAILLSYCGANYYGMQRNPG---MQTIEEELFKAMLKHKWITEDSFEQIQISCFQRAARTDKGVSAARQVCSVK-LPEELD-LEAFNADLPQQIRLFGVERVTKGFNAKDQCNARTYTYTLPTVAFAPFEEK--------------------------------------------------------------------------VDDVHDTFRISPELLQKVKETLKLYEGTKNFHNFTSKKSFLDPSSKRFIMSFTSSEP-FRSPQDIEFVTLKVKGQSFMLHQIRKMVGLAIAIVRGNTTAATLERALTE-ERLDLPMAPGLGLVLDTVHYERYNDRYGKDGIHNPLTWQAQEAQVQEFIEREIFSQIYKTEAEQRNMLDWIGTLHYHSYDTRTEDAPPPSSEDKKVKGGDDDNDE-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53167-1", "uniprot_id": "PUS2_YEAST", "id": "P53167-1", "name": "tRNA pseudouridine(27/28) synthase", "aln": "---------------------------------------------------------------------------------------------------------MLLGYCGSGYYGMQYNPP---HKTIEGEILTKLFDVGAISEENSLAPKKNSFMAAARTDKGVHAMLNLLSLKITLR-EDTVAKLNAALPPEIRVWGIQPVNKKFNARSACDSRWYQYLIPEFILIGPPRSSLLHRNVG-------GCYREDG-SQEVWDTFLEQTRGRFSGDELCRLQDTAQKLS-------ESDPLVQDYVGLLSGTLSGYCLSPSKLDAFEAAMQEYVGTHNFHNFTTGKLWGDPSAQRHIKKVVVS------QASPGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLLYCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNRL--------------ATPLI--------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12211-1", "uniprot_id": "PUS1_YEAST", "id": "Q12211-1", "name": "tRNA pseudouridine synthase 1", "aln": "---------------------------MSEENLRPAYDDQVNEDVYKRGAQSKLTKARKADFDDEKDKKKDNDKHIDKRPKSGPRLDENGNPLPKEPRLPKRKVAVMVGYCGTGYHGMQYNPP---NPTIESALFKAFVEAGAISKDNSNDLKKNGFMRAARTDKGVHAGGNLISLKMIIEDPDIKQKINEKLPEGIRVWDIERVNKAFDCRKMCSSRWYEYLLPTYSLIGPKPGSILYRDIEESKTELPGVLDEDLESKEFWEEFKKDANEKFSTEEIEAILAYVPPARDEFDINEELYQKVKKYKQLENAHRRRYRISAAKLAKFRASTSQYLGAHNFHNFTLGKDFKEPSAIRFMKDIKVSDPFVIGDAQTEWISIKIHGQSFMLHQIRKMVSMATLITRCGCPVERISQAYGQ-QKINIPKAPALGLLLEAPVFEGYNKRLEQFGYKAIDFS-KYQDEVDKFKMKHIYDKIYKEEVDENVFNAFFSYIDSFNKVTGAQGEETADKSGPAVQKSIFEFLTAKGIPGLTDAPESNKKIKQRKRMEEEEAASKKAEISSTTQSNEPEVQPEAAAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::.*.* .*:*** * *** :.. :. *.: : * .******* * :: *:* : :* ** **: . : *. *:.:. * :* * * :* : . : ::. * .. * *::****** * :**: *.: . : : ::*****:****:*:.:. .: : . : :* **. **:*: :: ** : : * . * * * :.. : :. : ", "identical_positions": 69, "similar_positions": 77, "identity": "11.98%" }, { "cls_id": "homologset.agr.MGI:1929242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12007-1", "uniprot_id": "IVD_RAT", "id": "P12007-1", "name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "aln": "---MATAVRLLGRRVSSWRLRPLPSPLAVPQRAHSMLPVDDDINGLNEEQKQLRHTISKFVQENLAPKAQEIDQSNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASAAVGLSYGAHSNLCINQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMRLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDLTAVPASRGITAFIVEKDMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANILSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMACRQYVYNVARACDEGHITAKDCAGVILYTAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGGGTSEVRRLVIGRAFNADFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHI5-1", "uniprot_id": "IVD_MOUSE", "id": "Q9JHI5-1", "name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "aln": "---MATAIRLLGRRVSSWRLRPSPSPLAVPRRAHSILPVDDDINGLNEEQKQLRHTISKFLQENLAPKAQEIDQTNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCVNQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMKLKAEKKGDHYVLNGNKFWITNGPDADILVVYAKTDLTAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANVLSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMASRQYVYNVAKACDEGHIIPKDCAGVILYAAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26440-1", "uniprot_id": "IVD_HUMAN", "id": "P26440-1", "name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "aln": "MAEMATATRLLGWRVASWRLRP-PLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSL9-1", "uniprot_id": "Q9VSL9_DROME", "id": "Q9VSL9-1", "name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "aln": "-----MALRFVAQSCRSLLQRGDRPLSWTRTLAH--YPVNDAMFGLDEDRQKLREVAFNFFQKELAPLAKEIDKLDNFKDMRPFWKKLGALGFLGITAEPDFGGTGGSYLDHCIIMEEFSRAAGGVALSYGAHSNLCINQLTKNGTPEQKEKYLPKLCSGEHVGGLAMSEPGAGSDVVSMKLRAERKGDYYVLNGSKFWITNGSDADTLIVYAKTGGSGVPDKHGITAFIVETAWEGFSVAQKLDKLGMRGSSTCELVFQDLKVPAKNILGQENRGVYVLMSGLDFERLVLAAGPVGLMQAACDVAFDYAHQRKQMNKLIGEFQLLQGKMADMYTTLSACRSYLYTVARSCDAGNRSPKDCAGVILYTAEKATKVALDAIQILGGNGYINENPTGRILRDAKLYEIGAGTSEIRRWLIGRQLNQEYK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *::. * * . ** **:* : **.*::::**.. :*.*:.*** *:***: ::**::* ***:** **.***** ::**:* .**:* ::***:***:..*.**********:**:.:**. ********* ***.:*.******.********:*:**:**::*:***.*******.*** *:*****. :.** .:********. ***.::**********.****:*:* *:** *:*.:*.:**********:******.**:*:***. * :: * * *: :.: **.***:********* * *.*.*:*.**::** *: .*********:** **:****.** :*******: * **:**********.****:** :*** :* :::", "identical_positions": 251, "similar_positions": 107, "identity": "58.78%" }, { "cls_id": "homologset.agr.MGI:1929253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNM9-1", "uniprot_id": "GLTP_RAT", "id": "B0BNM9-1", "name": "Glycolipid transfer protein", "aln": "----MALLAEHLLKPLP-------ADRQIETGPFLEAVAHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTDPAKFKTLQNILEVEKGMYGAEWPKVGATLALLWLKRGLRFIQVFLQSICDGERDENHPNLIRVNANKAYEMALKKYHGWLVQKIFKAALYAAPYKSDFLKALSKGQNVTEEECLEKIRLFLVNYTATIDAIYEMYTKMNAELDYTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL62-1", "uniprot_id": "GLTP_MOUSE", "id": "Q9JL62-1", "name": "Glycolipid transfer protein", "aln": "----MALLAEHLLKPLP-------ADRQIETGPFLEAVAHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTDPAKFKTLQNILEVEKGMYGAEWPKVGATLALLWLKRGLRFIQVFLQSICDGERDENHPNLIRVNANKAYEMALKKYHGWLVQKIFKAALYAAPYKSDFLKALSKGQNVTEEECLEKIRLFLVNYTATIDAIYDMYTKMNAELDYTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZD2-1", "uniprot_id": "GLTP_HUMAN", "id": "Q9NZD2-1", "name": "Glycolipid transfer protein", "aln": "----MALLAEHLLKPLP-------ADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKIRLFLVNYTATIDVIYEMYTQMNAELNYKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BG43-1", "uniprot_id": "GLTP_DANRE", "id": "A2BG43-1", "name": "Glycolipid transfer protein", "aln": "----MALLMEHQFRQLP-------ADKQVETRPFLEAVSHLPPFFDCLGSAVFSPIKADIAGNITKIKAVYDSNPTRFKTLQQILEAEKEMHGAEWPKVGATLALMWLKRGLRFIQVLLQSLVDGDKDDNNPNLIKVNVTKAYEMALKKYHGWIVQKLFQAALYAAPYRSDFLRALSKGREVKDEECLDKVRQFLVNFTATNDAIYEMYTKMNADLDYKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UV97-1", "uniprot_id": "A0A8N7UV97_DANRE", "id": "A0A8N7UV97-1", "name": "", "aln": "----MALLLDQQFAPLS-------DTKEIATKTFLESVSHLPPFFDCLGSKVFAPIKSDINGNITKIKAVYDSDPVKYETLQQILIIEKSSYGSEWPKVGATLALMWLKRGLRFIQILLQSLADGERDEDNPNLIRVNITKAYDQALKRYHGWIVQKVFKAALFAAPCRSDFLKALSKDQEVAEEDCLAKVRQFLINFTATVDAIYEMYSTMNAELDYLV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXV1-1", "uniprot_id": "Q9VXV1_DROME", "id": "Q9VXV1-1", "name": "Glycolipid transfer protein domain-containing protein", "aln": "MAASEGSAARIQFKALRGFPAIGDTADKLETQAFLDASKEIVTVIESFG-KLFTPVISDMNGNINKLTKAYGADVVKYQYLEDLIVLNVN------VDDFAANALLWLKRGLQLICTFFENIYN---DAQAKEALKQHLQDAYERTLKPYHGFIVQSTIKIIYSWVPTRSQLL-----GQGVAQAENIEVLTSFLPRMRAHLDSIDALLKAHNLDDARKV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :: * .**:: .: ..::.:* :*:*: :*: ***.*:. .*.:: .::. *:::: : . *: **:******::* :::.: : * : : :: : .**: :** ***::**. :: .* :*::* .: * : : : : ** . * * * : . * : *", "identical_positions": 45, "similar_positions": 74, "identity": "20.45%" }, { "cls_id": "homologset.agr.MGI:1929258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM47-1", "uniprot_id": "CSEN_RAT", "id": "Q9JM47-1", "name": "Calsenilin", "aln": "---------------------------------------------------------------------------------------------------------MQRTKEAMKASDGSLLGDP----------GRIPLSK---REGIKWQRP-RFTR--QALMRCCLIKWILSSAAP---------------------QGSD---SSDSELELSTVRHQ-----------------------------------PEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD-ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMSSM----------QLFENVI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXT8-1", "uniprot_id": "CSEN_MOUSE", "id": "Q9QXT8-1", "name": "Calsenilin", "aln": "---------------------------------------------------------------------------------------------------------MQRTKEAVKASDGNLLGDP----------GRIPLSK---RESIKWQRP-RFTR--QALMRCCLIKWILSSAAP---------------------QGSD---SSDSELELSTVRHQ-----------------------------------PEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD-ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM----------QLFENVI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2W7-1", "uniprot_id": "CSEN_HUMAN", "id": "Q9Y2W7-1", "name": "Calsenilin", "aln": "---------------------------------------------------------------------------------------------------------MQPAKEVTKASDGSLLGDL----------GHTPLSK---KEGIKWQRP-RLSR--QALMRCCLVKWILSSTAP---------------------QGSD---SSDSELELSTVRHQ-----------------------------------PEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGD-ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSM----------QLFENVI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGD4-1", "uniprot_id": "A0A8M2BGD4_DANRE", "id": "A0A8M2BGD4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MQ---EDGKVVDGTLLGDA----------NGVEPGRGRQKESGKWQRP-RFTR--KALMRCCLVKWIIASTGP---------------------KEQDGEYSSDSDLELSTVRHQ-----------------------------------PEGLEQLQAQTKFTKKELQSLYRGFKNECPSGLVDEETFKTIYSQFFPQGD-ATTYAHFLFNAFDLDRNGSIRFEDFVIGLSVLLRGTVTEKLNWAFNLYDINKDGYITKEEMLLIMKSIYDMMGRYTYPSVRDEAPSEHVEKFFQKMDRNRDGVVTIEEFIETCQKDENIMNSM----------QLFENVI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IR92-1", "uniprot_id": "Q8IR92_DROME", "id": "Q8IR92-1", "name": "EF-hand domain-containing protein", "aln": "MAGPQVQHSQRPNSAYYTGLNGGSGSGGGGGGGGAGGGGAGGGSSAGMSSSASHTGLHALRQVSNETELIYRGSHSNGTVNELPSSAQHHLLTGRAVQQHQQQQQMHHQTVSSIAGTGSSVTDALISTINSGGGGGGPSGSSCSTAALGIKKS-STQRSIEIIVDASQCGKELVASGPGSGAAGSGAAIVSTLDVEDVEQGGGGQESSSSHRKSSRHRHRPLHRRLITYLRNLFQGSTTQNDSELEEFETPARYRPDSLSALSRATRFTEDEIKRIYRGFKAECPTGVVKEDTFKVIYSQFFPQGANPTLYAHYVFNTLDQDHSGIVSFEDFVQGLSILSRGSVEEKLRWTFSLYDINGDGFITREEMTDIVTAIYELMGRLPDECPEEEKIKGKVEQIFQKMDTNRDGVVTLEEFLEACRNDDAISRSMSYTVPRRRRHQLSAQQQHLQHQKHQQQEPEKRKSNHKTKNKQQQKQQQPHSTRHQNCCHIIDMDGDSTTSTTTASAATGTTLNCNVLYDYGAAEEDDDDQDEDDEDSDEEYRSFVCRHCQRSQSVVQQPRSNRRSQSQSKSRKRSKSRKRHQSKQGHHQGQQGHQGHHGQQLTRWPEINVANEQAIRFRCPQVGPQVGRDLHTPQPMHFHHPQSQSQKAKSKSRPRKHRACPPASLSKAGAAAAAAAPGPPAPPAPPADPSQLPPSEQHPLAPLNVIVGGAEVEVDPQQPQPPTTPDSPSLVTVSTWYTVAKQGVSC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBL2-1", "uniprot_id": "Q9VBL2_DROME", "id": "Q9VBL2-1", "name": "EF-hand domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MASPP-----------------------------------------------ESPIEEVVYELEHTRVPKP----------------------------------IPVALEDLCRQTKFTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKFFPHGN-SSLYAHYVFKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILAIHELMGRRPHQPEDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSL----------QMFDNDLXX-----------------------QEGELEPGLRNSRTIISLIDL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : : * .*. * *:**:.*:: :***** *** *:*.*: ** **::***:* .: ***::*:::* : .* : *.*:: ** * **:* *:*.*:*.***:* ** *:: *: *: :*:::*** . : :*::.*.*:* *:**::*::**:*:* :*: : *: *: : ", "identical_positions": 72, "similar_positions": 69, "identity": "9.64%" }, { "cls_id": "homologset.agr.MGI:1929259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7KTW2-1", "uniprot_id": "Q7KTW2_DROME", "id": "Q7KTW2-1", "name": "", "aln": "------------------------------------------------------------MEMLKYVIS------------------DNNYSWWI--KLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTITVCNMNQAK---KSKVEHLMPGSIRYAMLQKTCYKESNFSQYMDTQHRNETFSN--------------------------FILDVSEKCADLIVSCIFHQQRIPCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSDRFADIA-----------VDWDPISGYPQR-----LPSSYYPRPGVGVGTSMGLQIVLN-GHVDDYFCSSTNGQGFKI------LLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFYR-----YYTRRNCEAECDSMFFLRLCSCIP--YYLPLIYPNASVCDVFHFECLNRAESQIFD---------------LQSSQCKEFCLTSCHDLIFFPDAFSTPFSQK-DVKAQTNYLTNFSSEYMR--KNLAVVNFFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEIIYIILFVSTLLLILIF------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W250-1", "uniprot_id": "Q9W250_DROME", "id": "Q9W250-1", "name": "", "aln": "---------------------------------------------MEPSPSAGTERQGSSLFLLKSFVRSLRQFLNQTSLHGLKFVGDSGLSSWE--RSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATSILKVPFPAITICNMNQVQ---RSLVANYREGSNESALLKLLCESDSWESSEADEEFSASNFVTNNL-------------------KISEFVSNHSQSCERMLLFCRFSAVERNCSQLFQQILTDEGLCCVFNFQPPEYLYKPFANNNRNLTNSDGFES-------------VMWDPESGYPEQ-----LPPKFYPATASGTGITLGFTAVLD-AEMGEYYCSSTNGPGFKV------YFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEAVPAIRSISRDGRQCLFKNEKELIFYR-----IYTRLNCENECLAAFLYDTCSCIP--FDHPLIYSNASICSMGDTSCVRRAQRASNR---------------PGWAKCRQQCLPSCFDLNYLASGFSFPLASN-NFQLANALVESFNKSYLS--KNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPLAELFVWKRSSH--------VDSEKSLKHNAFGIEKGQSSDNPSFWHSKELYPKGVSISAYENAKSTKGLNYQ-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86LG1-1", "uniprot_id": "PPK28_DROME", "id": "Q86LG1-1", "name": "Pickpocket protein 28", "aln": "-------------------------------MRTLTESRRRQSGSSGCKKDSESDDDENTICSRAAIKRSVVYYLKNSTLHGLKYIAEESITIPE--RIFFGLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPFPAITICNLNQAL---LSKVDRIGRTSTNFSLLMGLCDQGG--DTTISYIGTWKYFKA--------------------------ILVDVAQPCEKMLLYCSFGSREEDCSWLFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPNTRYEL-----------IDWTPEKGYARN-----LPEFYFPRTSGGTGIRMGLTVVLN-ASIAEYYCTKSMSVGFKV------LVHNPAELPKVSNYGFVVTAGREARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYR-----TYSRKNCELECEAKLLLRECSCVL--YYLPRIDPLARVCGPNDNQCTDRVQTEIES---------------SLTNLSCENCWPGCFELTYRATLSTASIVSDPRFQAGENLPEYIFHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIFFYITVRPYCASRTLRQRHKRRLEQLSWLTPIRMPVRRALRRNRGGLLRNPPPPAYSDLQKFRGKLDKPETCKRKLWRTLQVRPVVDRADEELPTYPYLD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KHW3-1", "uniprot_id": "Q0KHW3_DROME", "id": "Q0KHW3-1", "name": "", "aln": "--------------------------------MRVPRNRQRAFFASQQKRSRPQHLQITLSTWRRILSRNTDEFCRNTTIHGLKYINNSKLRSSD--RLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSIANEPFPAVTICNLNQAL---AERVEHFSNDSVEFAMLQLLCRRKVDVELVKTNDSRWEEFILN-----------------------------ISQPCNSMVIHCRFGADDYECARLFHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNISLP-EGFHA-----------VNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLD-VQADAYYCSSSSSIGFKI------ALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWFA-----HYTQRNCVAECLSGWLIRHCGCVT--FYMPRLNANDTICPLHKRECVELIRFRTII---------------AMES-CLDECLPSCFDLSFSAIAYSTRISLDGFRETPSNGGWNFTDAYVER--SVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECVYFALIRPCRTCSEIRQLNQ--------------PRVHQMNLKRSPTPGNIRYISAADWFQAELAHQQPNNRQHFNPA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K691-1", "uniprot_id": "A0A0B4K691_DROME", "id": "A0A0B4K691-1", "name": "", "aln": "MTISDSELDSS----------------------KGIDLTFRRRRKAGS-------------VACEGFITTYHEYCRNTSIHGVQYLGEQERPFRE--RIFWLFVFLISIYGCSTLIQSAYTKWTETPVIVSFAEKSTPVWNIPFPAVTVCSETKRVLKQKGKETTYADLYSQFSEDMRASRVFRPENVSALEMEEFRTLLHVCNTQIIEEDIPLIAGDD---LDYFDVLQRMLPQFDRYFFYCRWLSRFGECETFFRKTLTEEGICYTFNGLRATEIYRDDTYQYQHSGEPLEMENISSQ--------HTAWTLETGYALD-----SDVETFPARVLSAGARSGIFLALQSFKQEVDYACRGPVQGFKVGKFENVLLHAPDDVPQVSKQFVRIPMGKEVLIAVKPNMITMSSGIAEYHPVRRQCFLSHERSLRFFK-----VYTESNCQLECLANFTLTKCGCVK--FSMPRN-VDMPVCGEDKIHCYDRAERELLVREFKRVKALNAGRENSRSVESACNCMPACTSLVYNTEISQANFDLEEMLVAEG--DTEFLKEYPGS--QMSRLSIYFKQSQFITSKRSELYGMTEFLANCGGIFGLFMGFSILSLVEMIYHFTLRLFTNLKR---------------------LVKG-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS73-1", "uniprot_id": "Q9VS73_DROME", "id": "Q9VS73-1", "name": "", "aln": "MSTDSTQPHTPSHEVAVRPPPCAANQWKRAALMARMAPAFRETVSDDSEDEVDTKKQIKYGSGFQAAKAIIHEYCDYTTIHGIRYLGEKKRPLLE--RLFWISVLVLSVFTCVKLTLNIWDKWNNNPVIVSFAEKSTPVWQIPFPAVTVCPETK----TRREIFNFTDSYHQVRDFQ--SNVSGIVDLSDKQKGLYGAVSQVCEPHLHDVTLGNKTRRG---MEIIDALTEVSPHFDDTYLNCKWRNSPVKCSDIFHKFVTEDGVCFSFNSLSPAEIFRAEGIIPDFIFR--EENRLS-----------MDWNVEDGYSAS-----ADTSPYPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPVQGFKI------LLHTPGDVAQVSKQYFRIPFDQEVLISIRPKIITTSDGLKHYEPNRRQCYFQKERELRYFN-----IYSQSNCELECLANFTLTKCGCVK--FSMPRN-VNMPVCGDASLKCYNQAEDELLLREFTQG-LVNAG-ENTR-GETECNCLPSCTSIAYEAEISQADFDYKTVINTDSPEGKEEQSKRQGM--KMSRVSIFFKEAQFLTSRRSELYGTTDFLANCGGLLGLFMGVSMLSIVELIYFCTVRLISNLRMRRKTRK--------------ELLKAVNKDA--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KT94-1", "uniprot_id": "Q7KT94_DROME", "id": "Q7KT94-1", "name": "", "aln": "MAEIREDEEEKKSGISILPGPELLALPG-----FDTRASIASAALSDVPSDVIIKSRIRYGSPLSACKGLLLEYAKSTTIHGIRYIFEVHRPIYE--KLYWLFFTCISVYFAVSLIWDTYLKWQESPVILGFDETLVPVHKIPFPTITICPEIK----MERNVFDYTNVSRQLWEEYK--QNGNISDLDDEDLARMAVAMHICDSEVVQRFTPLLSQLNPPNVDVTQTLIDLSISKNETGPFCKWNGRFYFCDKIFDFVATDEGICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPWNNITGNWSLDTGFVD------QGQNAYPQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYKV------FLNSPESVPLTTGNYILVPHGDEVLVSVLPAYVVSTDNLHEITPEKRQCLFDDERSLRFFR-----SYSQSNCQTECLANYTVSKCGCAK--FWMPKP-LGTPVCGLKDINCYTSAQDELYTLMQNQTMAKSID----ESVDITCNCMPACTSLEYNFEISRAKYDVAKTIRAFR-----EEYEHTDA--IGSRLSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISCLSFLELIYFFCMRICGSCRDRRKHKI--------------QQQNSVDLPEEKSEN---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9R0W5-1", "uniprot_id": "ASIC5_RAT", "id": "Q9R0W5-1", "name": "Bile acid-sensitive ion channel", "aln": "---------------------------------MEHTEKSKGPAEKGLLGKIRRYLSKRPLPSPTDRKKFDHDFAISTSFHGIHNIAQNQNKVR---KVIWLSVVLGSVSLLVWQIYSRLVNYFMWPTTT--SIEVQYVEKIEFPAVTFCNLNR------FQTEAVSRFGIIFFLWDIVSKVLRLQEISGNNTG-------------------------------------SPEALDFVASHRNFS---------ITEFVKNNGFYLNHDTLVHCEFFGKTCDPKDFKHVFTEYGN--------------CFTFNYGENVQ----------SKNKVSVSGRGLKLLLDVHQEEFTDNPVPGFADAGVIF------VIHSPKKEPQFDGLGLSSPVGMHARVTIR--------QLKTIHQEYPWGECNPDIKLRNFT-----TYSTYGCLKECKAKHIQRLCGCLP--FLLPGNGVECDLLKYYN--CVSPILDHIERKG------------LCTMGTHNSSCPVPCEETEYPATIAYSTFPSQRATKFLAKKLNQSQEYIREN---LVNIEINYSDLNYKITQQQKAVSVPELLADVGGQLGLFCGASLITIIEIIEYLFTSFYWVFIFFLLKIL--------------EMIQRTSPPQTV------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Y1-1", "uniprot_id": "ASIC5_MOUSE", "id": "Q9R0Y1-1", "name": "Bile acid-sensitive ion channel", "aln": "---------------------------------MEHTEKSQVHAEKGLLGKIKRYLSKRPLPSPTDRKKFDQDFAMSTSFHGIHNIAQNQNKVR---KVIWLAVVLGSVSLLVWQIYSRLVNYFTWPTTT--SIEVQYVEKIEFPAVTLCNLNR------FQTEAVSRFGIIFFLWDIVSKVLRLQEISANNTG-------------------------------------SPETLDFVTNHQNFS---------ITEFVKNNGFYLNNDTLVHCEFFGKTCSPKDFKHVFTEYGN--------------CFTFNYGENIQ----------NKNKVSVSGRGLKLLLDVHQEEFTDNPVPGFADAGVIF------VIHSPKKEPQFDGLGLSSPVGMHARVTIR--------QLKTVHQEYPWGECNPNIKLRNFI-----TYSTYGCLKECKARHIQRLCGCLP--FLLPGNGVECDLLEYYN--CVSPILDHIERKG------------LCTMGTHNSSCPVSCEETEYPATVSYSTFPSQRATRFLAKKLNQSQEYIREN---LVNIEINYSDLNYKITQQQKAVSVPELLADVGGQLGLFCGASLITIIEIIEYFFTNFYWVLIFFLLKIL--------------ETIQRTSPPQAV------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY37-1", "uniprot_id": "ASIC5_HUMAN", "id": "Q9NY37-1", "name": "Bile acid-sensitive ion channel", "aln": "---------------------------------MEQTEKSKVYAENGLLEKIKLCLSKKPLPSPTERKKFDHDFAISTSFHGIHNIVQNRSKIR---RVLWLVVVLGSVSLVTWQIYIRLLNYFTWPTTT--SIEVQYVEKMEFPAVTFCNLNR------FQTDAVAKFGVIFFLWHIVSKVLHLQEITANSTG-------------------------------------SREATDFAASHQNFS---------IVEFIRNKGFYLNNSTLLDCEFFGKPCSPKDFAHVFTEYGN--------------CFTFNHGETLQ----------AKRKVSVSGRGLSLLFNVNQEAFTDNPALGFVDAGIIF------VIHSPKKVPQFDGLGLLSPVGMHARVTIR--------QVKTVHQEYPWGECNPNIKLQNFS-----SYSTSGCLKECKAQHIKKQCGCVP--FLLPGYGIECDLQKYFS--CVSPVLDHIEFKD------------LCTVGTHNSSCPVSCEEIEYPATISYSSFPSQKALKYLSKKLNQSRKYIREN---LVKIEINYSDLNYKITQQQKAVSVSELLADLGGQLGLFCGASLITIIEIIEYLFTNFYWICIFFLLKIS--------------EMTQWTPPPQNHLGNKNRIEEC--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAJ7-1", "uniprot_id": "Q9VAJ7_DROME", "id": "Q9VAJ7-1", "name": "", "aln": "-----------------------MLYPLELPRARRPLYRDYGGKSGLIQTQRDARKNSRLGKLWHFMLPYLKDYAAESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLNELYQTVRIQTTIKNTMLPIFRIPFPSIGLCPRNRLN----WKILETEAVDHFLGANVSAAQKDLFVKFFTAAGD---------------------------------------PHLSRLNEMSNFFGNKTLTDELHMLDHLDLREVYKFIQFRCQDLFHTCRWRGNPVNCCEVIEYQFTEAG-------LCFVFNTEISPASRQKAREDKYYPLRTPHYGEGSGLDLFLR----LNRSFIRPGKRGINV------MIKQPQQWSDVVR---HVPHEAHTRISITPRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDKDNFTACKASDFKCLYDNRFTFSIERHPEEDDFVKN---PFKESMICDCFTSCSQLVFDRVFTTTTLDNNETDTEAG----------------TMRLDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLGASLLSAFELAYYFSIGLYLYIHGKRKLRK--------------PEPGVLTIQFGQRKITPIKF----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . **:: .* : . : : : : . : : * . . * . . .. : : . : * .* .* * * : * * * . : : . . : ::. ** .*: * * : * ", "identical_positions": 19, "similar_positions": 42, "identity": "2.66%" }, { "cls_id": "homologset.agr.MGI:1929260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AK45-1", "uniprot_id": "A0A8I6AK45_RAT", "id": "A0A8I6AK45-1", "name": "Mitochondrial carrier homolog 2", "aln": "----IYNSVVPVVSSLTLPLPSGSPHHHHIITIPLPTPSGHFRLAQAQEKSPFPVARGTHTHTHARPAHKPRPRRLLASACRFFRRASGRGLSGRRAAGGPVKPAPPTRDLEPAVSLGDSVCPSVRGCHHGGRGQSGAPGLRSHHPVPAAHVGYEPLPPTIG--RNIFGRQVYQLPGLFCYAQHIASIDGKRGLFTGLTPRLCSGVLGTVVHGKVLQYYQECEKPEDLGSANVQKEYPSSFDRVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGSPPYSPIYTSWIDCWCMLQKAGNMSRGNSLFFRKVPCGKTYYCDLRMLI-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q791V5-1", "uniprot_id": "MTCH2_MOUSE", "id": "Q791V5-1", "name": "Mitochondrial carrier homolog 2", "aln": "-----------------------------------------------------------------------------------------------------------MADAASQVLLGS------------GLTILSQP---LMYVKVLIQVGYEPLPPTIG--RNIFGRQVCQLPGLFCYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQYYQESEKPEELGSVTVQKEYSSSFDRVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGSPPYSPIYTSWIDCWCMLQKAGNMSRGNSLFFRKVPCGKTYCYDLRMLI-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6C9-1", "uniprot_id": "MTCH2_HUMAN", "id": "Q9Y6C9-1", "name": "Mitochondrial carrier homolog 2", "aln": "-----------------------------------------------------------------------------------------------------------MADAASQVLLGS------------GLTILSQP---LMYVKVLIQVGYEPLPPTIG--RNIFGRQVCQLPGLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLKMLI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3Y4-1", "uniprot_id": "Q9V3Y4_DROME", "id": "Q9V3Y4-1", "name": "", "aln": "-----------------MAG----------FP-------EHAR--------------------------------------------------------------AEDTEVNVWIRFGLR----------LGVSAALHP---FEYSKTLIQLGYEPIAPLP--GKSILGKPIMKLPNIFQYAGHIRRIDGFYGCYRGLAPKLVGSLVAMVVSDRVADQLGLE--QPEENKDDSQLSDEELYVQFKKSLKRDIVLMVSGVVASHPFHVISLRMMAQFVGRETLYTSIVGSVAEIWKSEGIAGFFAGLVPKLLGDLACLVLSSSTIYILNKYIIKDKLG-----RQYNSGFTQFAVSSLLYPLQVVSTCSAVSGSRLMAAQPPIMPAYRNWVDCWNDLQVRGELKRGSSLFWRSQSISSPVIATSFAPLPKLARYQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3P6-1", "uniprot_id": "Q9W3P6_DROME", "id": "Q9W3P6-1", "name": "", "aln": "MAHREYNRRDGQAEGLGLGGGDADNSVRMRHPTPPPLAVQHARSGAMVVELAVDPSRAMRSTNQQQPIDRDQLRISTEESC--------QGSELVVASSHLSKKIQEHRRPNQLVRFCLR----------LGYNTLLYP---YEMAKVLIQLGHEPLQAKPFVMRLIQRRPRLFLPSVHRYVQHIQHIDGYTGMYRGLTARLAASIVDYLLGDLLLATLHFA--PYKRGPKEG-LS----LKEFWWNLTRNSLRITTVVVITHPFYVVMVRQIAQFVGGEHVYEGLVGSLMTLAQQEGCAGLFAGMVPRLLGEWSVLFITSALSHLCRRLLPMSELQ-----HQYNTAVIQMMASLVAYPLEVTSTCMAGTGAPLTACEPPSMPLYNHWVDCLTDLYARGGQNRGAILFWRTVPKIQLLRSKDNYTVRSI----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * ::*:**: . : * : **.:. *. ** *** * : **:.:* ..:: :: . : . . . .. . .*: : : .: :***:*: :* :.**:* * * .: .*: : :.** *:***::*:***: * : .: :: . . : :.*. .. : .* : **: :.*. * ... * . ** * * *:** * * .** **:*. . . : ", "identical_positions": 62, "similar_positions": 87, "identity": "14.29%" }, { "cls_id": "homologset.agr.MGI:1929261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q791T5-1", "uniprot_id": "MTCH1_MOUSE", "id": "Q791T5-1", "name": "Mitochondrial carrier homolog 1", "aln": "-----MGASDPEVAPWAPGG-----AAGMAGAGAGAGARGGAPAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGPGAPGS-------------GDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTN--VLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTS--LKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLRAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZJ7-1", "uniprot_id": "MTCH1_HUMAN", "id": "Q9NZJ7-1", "name": "Mitochondrial carrier homolog 1", "aln": "-----MGASDPEVAPWARGG-----AAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGSGGLGS-------------GDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTN--VLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTS--LKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3Y4-1", "uniprot_id": "Q9V3Y4_DROME", "id": "Q9V3Y4-1", "name": "", "aln": "--------------------------------------------------------MAGFPEHAR--------------------------------AEDTEVNVWIRFGLRLGVSAALHPFEYSKTLIQLGYEPIAPLPGKS--ILGKPIMKLPNIFQYAGHIRRIDGFYGCYRGLAPKLVGSLVAMVVSDRVADQLGLEQPEENKDDSQLSDEELYVQFKKSLKRDIVLMVSGVVASHPFHVISLRMMAQFVGRETLYTSIVGSVAEIWKSEGIAGFFAGLVPKLLGDLACLVLSSSTIYILNKYIIKDKLG----------------------RQYNSGFTQFAVSSLLYPLQVVSTCSAVSGSRLMAAQPPIMPAYRNWVDCWNDLQVRGELKRGSSLFWRSQSISSPVIATSFAPLPKLARYQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3P6-1", "uniprot_id": "Q9W3P6_DROME", "id": "Q9W3P6-1", "name": "", "aln": "MAHREYNRRDGQAEGLGLGGGDADNSVRMRHPTPPPLAVQHARSGAMVVELAVDPSRAMRSTNQQQPIDRDQLRISTEESCQGSELVVASSHLSKKIQEHRRPNQLVRFCLRLGYNTLLYPYEMAKVLIQLGHEPLQAKPFVMRLIQRRPRLFLPSVHRYVQHIQHIDGYTGMYRGLTARLAASIVDYLLGDLLLATLHFAPYKRGP-----KEGLSLKEFWWNLTRNSLRITTVVVITHPFYVVMVRQIAQFVGGEHVYEGLVGSLMTLAQQEGCAGLFAGMVPRLLGEWSVLFITSALSHLCRRLLPMSELQ----------------------HQYNTAVIQMMASLVAYPLEVTSTCMAGTGAPLTACEPPSMPLYNHWVDCLTDLYARGGQNRGAILFWRTVPKIQLLRSKDNYTVRSI----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :. . : . * * .: :* * ***:*:**: . : : : **... *. :* ::** * :***:.:* .. : : . : : :. . :. . . : : : :**::*: :* :.**** * * .::.*: : :.** *:*.*::*:***: * . :: . : ..: :.*.. . : .* : **: :.. * ... * * ** * :. *:.* . * .:* **: *::* . . . ", "identical_positions": 60, "similar_positions": 103, "identity": "14.02%" }, { "cls_id": "homologset.agr.MGI:1929264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1T2-1", "uniprot_id": "SAE1_MOUSE", "id": "Q9R1T2-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVEKEEAGGGGGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVSPEDPGAQFLIQTGSVGRNRAEASLERAQNLNPMVDVKVDTEDVEKKPESFFTKFDAVCLTCCSRDVIIKVDQICHRNSIKFFTGDVFGYHGYTFANLG----EHEFVEEKTKVAKVSQGVEDGPEAKRAKLDSSETTMVKKKVLFCPVKEALEVDWSGEKAKAALKRTAPDYFLLQVLLKFRTDKGRDPTSESYKEDAELLLQIRNDVFDSLGISPDLLPDDFVRYCFS----EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECLGPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXQ0-1", "uniprot_id": "SAE1_RAT", "id": "Q6AXQ0-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVEKEEVSGGGGG-ISEEEAAQYDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVSPEDLGAQFLIRTGSVGQNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTEFDAVCLTCCSKDVIIKVDQICHRNSIKFFTGDVFGYHGYTFANLG----EHEFVEEKTKVTKVSQGVEDGPDAKRAKLDSSETTMVKKKVLFCPVKEALAVDWSGEKAQAALKRTAPDYFLLQVLLKFRTDKGRDPTSDSYSEDAELLLQIRNDVFDSLGVSPDLLPDDFVRYCFS----EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECLGPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBE0-1", "uniprot_id": "SAE1_HUMAN", "id": "Q9UBE0-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVEKEEAGGG----ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLG----EHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFS----EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQS6-1", "uniprot_id": "SAE1_DANRE", "id": "Q6IQS6-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MIDTIEKEDT---IISEEEAAQYDRQIRLWGLDAQKRLRGSRVLLVGLRGLGAEVAKNLILAGVKGLTLLDHEQVTEESRRAQFLIPVDADGQNHAQASLERAQFLNPMVEVKADTEPVESKPDDFFFQFDAVCLTRCSRDLMVRVDQLCASRNIKVFCGDVYGYNGYMFSDLGQ---EYHYVEEKPKVVKGSNEANDGPEAKKPKIDPNETTMVKKTISFCSLKEALEVDWTTEKAKSSLKRIPADYFLLQVLLKFRTDKGRDPQPDSFAEDSQLLLQIRDDVLETMGLSSDLLPNTFVSYCFS----EMSPVCAVVGGVLGQEIVKALSQRDAPHRNFFFFDGLKGSGVVDYFSSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KSM5-1", "uniprot_id": "Q7KSM5_DROME", "id": "Q7KSM5-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVVDMDTSET-AVELTEAENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEEDFCSQFLVPRESLNTNRAEASLTRARALNPMVDISADREPLKEKTSEFFGQFDVVVVNGATNEELLRIDTICRDLGVKFIATDVWGTFGFYFASLQ----KHSYVEDVIKHKVVAN-------SEKKKKYETVSIPTQRDVDYPGYSAWLDFDVTEPSYLRKLKRNGPGVLLLSVLQKFRTTHKRDPSYKTREADLELLRGIRDELLPNS-----ILGDEALGLIFA----QISPAVAVVGGVVAQEVIKVVTKLEAPHRNLFVFDPETCAGYVEAIGAK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06624-1", "uniprot_id": "RHC31_YEAST", "id": "Q06624-1", "name": "DNA damage tolerance protein RHC31", "aln": "MDMKVE-------KLSEDEIALYDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGIGHLTILDGHMVTEEDLGSQFFIGSEDVGQWKIDATKERIQDLNPRIELNFDKQDLQEKDEEFFQQFDLVVATEMQIDEAIKINTLTRKLNIPLYVAGSNGLFAYVFIDLIEFISEDEKLQSVRPTTVGPISSNRSIIEVTTRKDEEDEKKTYERIKTKNCYRPLNEVLSTATLKEKMTQRQLKRVTSILPLTLSLLQYG-LNQKGKAISFEQMKRDAAVWCENLGVPATVVKDDYIQQFIKQKGIEFAPVAAIIGGAVAQDVINILGKRLSPLNNFIVFDGITLDMPLFEF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ::* * *********: :* .:* :::*: .: .:*:*::*.::*:*: :.:** . *: *. :**:: . : :*: * : *** :::. * : ::.* ..** :** * . : :::: : .: . . * .: * .* : ::. . : . . : * : . :.: . : .: : . . : : . :: : : : :::*. *::** :.*:::: : : .* .*::.** . : : ", "identical_positions": 51, "similar_positions": 113, "identity": "14.25%" }, { "cls_id": "homologset.agr.MGI:1929266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66X93-1", "uniprot_id": "SND1_RAT", "id": "Q66X93-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "-MASAQSSGSS-----GGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDGKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDT-NGENIAESLVAEGLAS-RREGMRANNPEQNRLSECEEQAKASKKGMWS-EGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDHYLVTVMLSGIKCPTFRRETDGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPR-------LEGD-NIQDK--NKKLRPLYDIPYMFEAREFLRKKLIGKKVSVTVDYIRPASPATET-VPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAK-QFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPG--LVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAG-NFIGWLHMD-GANLSVLLVEHALSKVHFTAERSAYYKPLLSAEEAAKQRKEKVWAHYEEQPVEEVMPVLEEKE------RSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRSDISSHPPVEGAYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGALPPAFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQNTQCLLNVEHLSASCP-HVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78PY7-1", "uniprot_id": "SND1_MOUSE", "id": "Q78PY7-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MASSAQSSGSS-----GGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDGKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDT-NGENIAESLVAEGLAT-RREGMRANNPEQNRLSECEEQAKASKKGMWS-EGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPGHHLVTVMLSGIKCPTFRRETDGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNLLGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPR-------LEGD-NIQDK--NKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATET-VPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAK-QFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPG--LVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAG-NFIGWLHMD-GANLSVLLVEQALSKVHFTAERSAYYKPLLSAEEAAKQRKEKVWAHYEERPVEEVMPVLEEKE------RSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDISSHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQNTQCLLNVEHLSASCP-HVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KZF4-1", "uniprot_id": "SND1_HUMAN", "id": "Q7KZF4-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MASSAQSGGSS-----GGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDT-NGENIAESLVAEGLAT-RREGMRANNPEQNRLSECEEQAKAAKKGMWS-EGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPR-------LEGE-NTQDK--NKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATET-VPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAK-QFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPG--LVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAG-NFIGWLHID-GANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKE------RSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCP-HVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZT42-1", "uniprot_id": "SND1_DANRE", "id": "Q7ZT42-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MASAVPAQVQS-----SQASAPQLQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGALARRAIQGQPDTKDTPDEPWAFQAREFMRKKVIGKEVCFTVENKTPQGREYGMVYLGKDT-SGENIAESLVAEGLAMVRREGIRGNNPEQVRLCDLEDQAKSSKKGLWS-EGGGSHTIRDLKYTIENPRNFVDSLHQKPVNAIIEHVRDGCMVRALLLPDYYLVTVMLSGIKSPTFKREADGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCPNQVILGTILHPNGNITELLLKEGFARCVDWSMAVYTQGAEKLRAAERSAKERKVRIWKDYVAPTANLDQKDRQFVAKVMQVVNADAIVVKLNSGEYKTIHLSSIRPPR-------LEGEEKNKDK--DKRFRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRAATNAMEMGVPAFPERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGETQKAK-QFFPFLQRAGRSEAVVEYVFSGSRLKLYMPKETCLITFLLAGIECPRGSRNMPG--GMQVAEPYSEEAMLFTKELVLQREVEVEVESMDIAG-NFIDWLHID-GVNLSVALVENALSKVHFTAERSSYYKTLVSAEESARQRKEKLWANYEEKPNEEVAQVTEAKE------RGRNTDPSTSLEITDGLHFYAQDVETGTKLENLMESMRGEIAAQPPVEGSFAPRRGEFCIAKF-ADGEWYRARVEKVESPAKVHVFYIDYGNREVLSSTRLAALPPAFSTRTLPPQATEYAFAYIQVPQDEDARADAVDSVVRDIHNTQCLLNVEYSGMVCP-QVTLQFADTKEDVGLGLVKEGMVMVDIRKEKYLQKMVTEYLNAQESAKSARLNIWR----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0S7-1", "uniprot_id": "SND1_DROME", "id": "Q9W0S7-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MATAANTATAAGAAKDAPPAPTKSLSGIVKQVLSGDTVVIR-ATKGAPPPEKQITFSHVLAPKLARRPGAG---GDETKDEPWAWESREFLRKKLIGVEVTFTFDKPANSNREYGFVWIGKDKETGENVVESIVREGLVSVRREGRP--TAEQQTLIELEDQARAAGRGKWSPTASAADKVRNIKWSHENPAHLVDIYGGNPVKAIIEHVRDGSTVRAFLLPDFHYITLMISGIRCPGVKLDADGKPDLSVKVPFADEARYYVETRLLQRDVEIRLESVNNSNFIGTILYPKGNIAESLLREGLAKCVDWSMAVMKTGTDKLRAAERFAKEKRLRQWQDYQAKTPAFNSKEKDFSGTVVEVFNGDAINVRLSNGQVKKVFFSSIRPPRDQRAVVGTDGEEIVKAPPRGKNYRPLYEIPHMFDAREFLRKKLINKKVQCNLDYISPPR-------ENFPEKYCYTVSIGGQNVAEAMVAKGLATCVRYRQDDDQRSSAYDQLIAAEQQAIKGLKGLHAKKDNATLRVNDLTVDHSRIKVQYLPSWQRALRTEAIVEFVASGSRLRIFVPKDSCLVTFLLAGISCPRSSRPALNGVPAQEGEPFGDEALTFTRERVLQRDVSVHIDTTDKAGSSVIGWLWTDSGANLSVALVEEGLAEVHFSAEKSEYYRQLKIAEDRAKAAKKNIWTNYVEEVPKEKTVTEEEKEDKVVAERKVNYENVIVTEITETLTFFAQSVESGSKLESLMSKLHADFQSNPPIAGSYTPKRGDLVAAQFTLDNQWYRAKVERVQG-SNATVLYIDYGNKETLPTNRLAALPPAFSS--EKPYATEYALALVALPTDNEDKEEALRAFSEDVLNHKVQLNVELKVTGSPNLATLRDPTTKVDFGKQLVAEGLVLAEQRGERKLKELVDQYKAAQEAARVAHLAIWKYGDITQDDAPEFR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : : . .: . **:* **** ::::* .:*.****:**.:*:: * ****. .:* *****: :***:***:** ** **.:: : ..****::::***. .***:.**:* ***. **** ..** * : *:**::: :* ** ...:..:*::*:: *** ::** :**:*********. ***:***..: :*:*:***:.* .: ::**. .. *** **:::.*:*******:* *** *. ::****:*:***:* **:**:*:*****:** . *::******* ***:::* *:** . *. ::.*:::* ..*::*.*.*** *:*..*: *.:.:******* :*: : .*. ****:**:**:**********.***. .:*** .. *.*: * **:*** *:***:*:***** :*********** **:*:*** :***. ****:**: . ** *:: : .: * *::* *** *:**:**:* *****::::**::**:*******.***.:* . * .**:.:** **:* ****:*.*.::: * ** ..*.** * *.**** ***..*::***:**:* **: * **: *: *:::*::* *. :* . * ** * . . ***: * *:.*.**:*::**.**..:: :: ::**: *:::*:**:: *:* *.:****:**:*:. :: *:******:* *.:.**.:*.****: . *****:* : :* *:: : :*: :. .*: * : **** .* .**: . :* *.* ** **:*:.: * *: ::::: :* ***:*: *:* :*: ", "identical_positions": 411, "similar_positions": 290, "identity": "43.49%" }, { "cls_id": "homologset.agr.MGI:1929269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63524-1", "uniprot_id": "TMED2_RAT", "id": "Q63524-1", "name": "Transmembrane emp24 domain-containing protein 2", "aln": "-MVTLAELLVLLAALLA---TASGYFVSIDAHAEECFFERVTSGT-KMGLIFEVAEG-----GFLDIDVEITGPDNKGIYKGDRESS--GKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPK--------------GQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q3-1", "uniprot_id": "TMED2_MOUSE", "id": "Q9R0Q3-1", "name": "Transmembrane emp24 domain-containing protein 2", "aln": "-MVTLAELLALLAALLA---TASGYFVSIDAHAEECFFERVTSGT-KMGLIFEVAEG-----GFLDIDVEITGPDNKGIYKGDRESS--GKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPK--------------GQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15363-1", "uniprot_id": "TMED2_HUMAN", "id": "Q15363-1", "name": "Transmembrane emp24 domain-containing protein 2", "aln": "-MVTLAELLVLLAALLA---TVSGYFVSIDAHAEECFFERVTSGT-KMGLIFEVAEG-----GFLDIDVEITGPDNKGIYKGDRESS--GKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPK--------------GQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4K0-1", "uniprot_id": "Q9W4K0_DROME", "id": "Q9W4K0-1", "name": "", "aln": "MESTLAKVLLLVGSLLILCRTSHAFIVSVDAHNEECFFENVEGGT-KFGVTFEVIDG-----GFLDVDIKISGPDNHVMHESEKESS--GKYTFVAPAKGTYTVCFNNERSSMTPKLVMFSIDVGDAPQRAP-----------GAPGEEEVGHTKLEDMIRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWSTFEALVLVLMTVGQVYYLKRFFEVKRVV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32803-1", "uniprot_id": "EMP24_YEAST", "id": "P32803-1", "name": "Endosomal protein P24B", "aln": "-MASFATKFVIACFLFF---SASAHNVLLPAYGRRCFFEDLSKGD-ELSISFQFGDRNPQSSSQLTGDFIIYGPERHEVLKTVRDTSH-GEITLSAPYKGHFQYCFLNENTGIETKDVTFNIHGVVYVD------------------LDDPNTNTLDSAVRKLSKLTREVKDEQSYIVIRERTHRNTAESTNDRVKWWSIFQLGVVIANSLFQIYYLRRFFEVTSLV--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12403-1", "uniprot_id": "ERP3_YEAST", "id": "Q12403-1", "name": "Protein ERP3", "aln": "-MSNLCVLFFQFFFLAQFFAEASPLTFELNKGRKECLYTLTPEIDCTISYYFAVQQGE---SNDFDVNYEIFAPDDKNKPIIERSGERQGEWSFIGQHKGEYAICFYGGKAHDKIVDLDFKYNCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIERQLHVLERNIQYYKSRNTRNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFIFRESRKHNV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. : * . : ..*:: :. * . : . : : * .*: : :. . *: :: . .* : ** . : : *. . . : .::. : : :: : .* *: :: .*: *: :* : ::: : *: *. :*. ", "identical_positions": 18, "similar_positions": 62, "identity": "7.86%" }, { "cls_id": "homologset.agr.MGI:1929270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0P5-1", "uniprot_id": "DEST_MOUSE", "id": "Q9R0P5-1", "name": "Destrin", "aln": "-MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIVVEEGKEILVGDVGATITDPFKHFVGMLPEKDCRYALYDASFETK------ESRKEELMFFLWAPEQAPLKSKMIYASSKDAIKKKFPGIKHEYQANGPEDLNRTCIAEKLGGSLIVAFEGSPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7M0E3-1", "uniprot_id": "DEST_RAT", "id": "Q7M0E3-1", "name": "Destrin", "aln": "-MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIVVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETK------ESRKEELMFFLWAPEQAPLKSKMIYASSKDAIKKKFPGIKHEYQANGPEDLNRTSIAEKLGGSLIVAFEGSPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60981-1", "uniprot_id": "DEST_HUMAN", "id": "P60981-1", "name": "Destrin", "aln": "-MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETK------ESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03048-1", "uniprot_id": "COFI_YEAST", "id": "Q03048-1", "name": "Cofilin", "aln": "MSRSGVAVADESLTAFNDLKLG---------KKYKFILFGLNDAKTEIVVKET----------STDPSYDAFLEKLPENDCLYAIYDFEYEINGN----EGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGAGSH------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P45594-1", "uniprot_id": "CADF_DROME", "id": "P45594-1", "name": "Cofilin/actin-depolymerizing factor homolog", "aln": "-MASGVTVSDVCKTTYEEIKKD---------KKHRYVIFYIRDEKQIDVETVADR-------NAEYDQFLEDIQKCGPGECRYGLFDFEYMHQCQGTSESSKKQKLFLMSWCPDTAKVKKKMLYSSSFDALKKSLVGVQKYIQATDLSEASREAVEEKLRATDRQ-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWR1-1", "uniprot_id": "Q9VWR1_DROME", "id": "Q9VWR1-1", "name": "ADF-H domain-containing protein", "aln": "-MASGINLSRECQHVFEQIRKL---------KQHRYAVFVIQDEREIKVEVLGVR-------EANYDDFLADLQRAGSNQCRFAVYDYEYQHQCQGTLSTCLKEKLILMLWCPTLARIKDKMLYSSTFAVLKREFPGVQKCIQATEPEEACRNAVEEQLRSLDRE-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :: : ::: *: : :* : : : : : : :* :.::* .: : :.::.:: *.* * ::.**:*:*: .::: : *:. *.. .: .: *:: ", "identical_positions": 16, "similar_positions": 53, "identity": "9.3%" }, { "cls_id": "homologset.agr.MGI:1929274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00193-1", "uniprot_id": "SMAP_HUMAN", "id": "O00193-1", "name": "Small acidic protein", "aln": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0P4-1", "uniprot_id": "SMAP_MOUSE", "id": "Q9R0P4-1", "name": "Small acidic protein", "aln": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDEDD--SPDAESPDDSDSDSESEKEESAEELHAAEHPDDTEDPKSKKDAKSNYKMMFVKSSGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LGJ9-1", "uniprot_id": "A0ABK0LGJ9_RAT", "id": "A0ABK0LGJ9-1", "name": "Small acidic protein", "aln": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDEDD--SPDAESPDDSDSDSESEKEESAEELHAAAHPDDTEDPKSKKDAKSSYKMMFVKSSGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZVC9-1", "uniprot_id": "SMAP_DANRE", "id": "Q7ZVC9-1", "name": "Small acidic protein", "aln": "MSSSDEPC-KGTKRPASPDE-TGSTQWQSADLGTDERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRSGAEDRRMNADLEHQYQQSLDGKLSGRNRRHCGLGFSEPDEVAESPNAAVSETSNS-----SETPPEQVSETQKEEKPPASDTELEKPEPHT---HSKEDKKKTLKMAFVKST--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: *. :*.**.****: **::*::****.:*********************************:* **:::* :** *****:*.***** ********** :: . :.* .: .:. .*:* :. *:::.*:: .*.: . .. :.*:* *.. ** ****: ", "identical_positions": 92, "similar_positions": 52, "identity": "50.27%" }, { "cls_id": "homologset.agr.MGI:1929278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY73-1", "uniprot_id": "TMM59_MOUSE", "id": "Q9QY73-1", "name": "Transmembrane protein 59", "aln": "MAAPKGKLWVQAQLGLPPLLLLTMALAGGSGTAAAEAFDSVLGDTASCHRACQLTYPLHTYPKEEELYACQRGCRLFSICQFVDDGLDLNRTKLECESACTEAYSQPDEQYACHLGCQDQLPFAELRQEQLMSLMPRMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIFQSKPEIQYAPQLEQEPTNLRESSLSKMSYLQMRNSQAHRNYLEEEESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCAAVATAVEQYVPPEKLSIYGDLEFMNEQKLSRYPAPSLVIVRSQTEEHEEAGPLPTKVNLAHSEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKI3-1", "uniprot_id": "A0A8I6GKI3_RAT", "id": "A0A8I6GKI3-1", "name": "Transmembrane protein 59", "aln": "MAAPKGKLWVQAQVGLPPLLLLTMALAGGSGTAAAEAFDSVLGDTASCHRACQLTYPLHTYPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQPDEQYACHLGCQDQLPFAELRQEQLMSLMPRMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIFQSKPEIQYAPQLEQEPADLRQSSLSKMSYLQMRNSQAHRNYLEDEESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCAAVATAVEQYVPPEKLSIYGDLEFMNEQKLSRYPAPSLVVVRSQTEEHEEAGPLPTKPNSMS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXS4-1", "uniprot_id": "TMM59_HUMAN", "id": "Q9BXS4-1", "name": "Transmembrane protein 59", "aln": "MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHTYPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQLPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIFQSKPEIQYAPHLEQEPTNLRESSLSKMSYLQMRNSQAHRNFLEDGESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDLEFMNEQKLNRYPASSLVVVRSKTEDHEEAGPLPTKVNLAHSEI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.***::*:*******************:****************************************************:*******************.***********:*****************:*****************************************************:*****::**:*******************:**: **********************************:**********.*****************.****.***:***:**:********** * ", "identical_positions": 293, "similar_positions": 22, "identity": "90.71%" }, { "cls_id": "homologset.agr.MGI:1929280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Y1-1", "uniprot_id": "C56D2_RAT", "id": "Q641Y1-1", "name": "Transmembrane reductase CYB561D2", "aln": "MALSVET--------------------------------------------------ESHIYRALRTASGAAAHLVALGFTIFVAVLARPGSSLFSWHPVLMSLAFSFLMTEALLMFSPESSLLRSLSRKVRARCHWVLQLLALLCALLGLGLVILHKEQLGKAHLATRHGQAGLLAVLWAGLQCSGGVGLLYPKLLP-RWPLAKLKLYHATSGLVGYLLGSTSLLLGMCSLWFTANVTGGAWYLAVLCPILTSLVIMNQVSNAYLYRKRIQP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUE3-1", "uniprot_id": "C56D2_MOUSE", "id": "Q9WUE3-1", "name": "Transmembrane reductase CYB561D2", "aln": "MALSVET--------------------------------------------------ESHIYRALRTASGAAAHLVALGFTIFVAVLARPGSSLFSWHPVLMSLAFSFLMTEALLMFSPESSLLRSLSRKVRARCHWVLQLLALLCALLGLGLVILHKEQLGKAHLTTRHGQAGLLAVLWAGLQCSGGMGLLYPKLLP-RWPLAKLKLYHATSGLVGYLLGSASLLLGMFSLWFTATVTGGAWYLAVLCPILTSLVIMNQVSNAYLYRKRIQP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14569-1", "uniprot_id": "C56D2_HUMAN", "id": "O14569-1", "name": "Transmembrane reductase CYB561D2", "aln": "MALSAET--------------------------------------------------ESHIYRALRTASGAAAHLVALGFTIFVAVLARPGSSLFSWHPVLMSLAFSFLMTEALLVFSPESSLLHSLSRKGRARCHWVLQLLALLCALLGLGLVILHKEQLGKAHLVTRHGQAGLLAVLWAGLQCSGGVGLLYPKLLP-RWPLAKLKLYHATSGLVGYLLGSASLLLGMCSLWFTASVTGAAWYLAVLCPVLTSLVIMNQVSNAYLYRKRIQP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIT6-1", "uniprot_id": "Q9VIT6_DROME", "id": "Q9VIT6-1", "name": "ascorbate ferrireductase (transmembrane)", "aln": "MSDDK----------------------TKPTSV------------------------LQHIESALYVINQLCIGFVTIWISWTCLRQDLSGIRLHAW---LVTFGFVFLMAEGMMCFYDGSWLTVRYSRNYKTAFHVVLQILGGGMGVAGCLIQLIRDDWSISVTLHARLGFAAFVLCLIS--LLSGLVAFLARCLSR-TISPLVNKTFHVVLSFTAFVIAMMAQFYGYTQTGIFRGQGQ-DFVVLMQVVTMVLMVLTSIGAIKSLYQKIGSLAS-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIT5-1", "uniprot_id": "Q9VIT5_DROME", "id": "Q9VIT5-1", "name": "ascorbate ferrireductase (transmembrane)", "aln": "MSESKQPVLSRTQTSADYGSTLRTDTPRRPTFIPIESPRRYSKMAHGSLSGHEAENRLQRLEYFLNVLNQMCIGFITIYISYLTLRTGLSGTGLHAW---LVTIGFSFFMAEGVMIHYGGNVLTNGYKRQTKTTIHWVLLTLGGGCGAAGALIKMIQKGFLLQST-HGRLGMTAFVLCILA--MSSGLAALFSSRIKK-LITPLLNKTFHNFLGFACFVIALVTQYYGY-QTGYFKSRSETDFQILMKCLTLISLVLSSYGPMKALYQKCKNISQQF-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIU6-1", "uniprot_id": "Q9VIU6_DROME", "id": "Q9VIU6-1", "name": "ascorbate ferrireductase (transmembrane)", "aln": "MAEGYTKAT-----------------------------------------------AWLQIHSLLNSINHILIFLVAVFFFILARSLEFKDTAMHMF---MTGTGFHVLIAQAMMSHSKVNPLTRWLSHRNKSRFHAILQIVGGSMVLLGSLGKFSSKE-VHFNTWHGRVGGAASFFCAAS--IVGGFVNYFQPKFALKVMPPSELRFRHNLFGLVTFSLGMGAIYLGYYSKFFTK-YVDTDFIPGMMLITGIVYGLTIIAPVSSLLTKLKYRSKKKAEQAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . :: * . :::: : . :. : : .* .::::.:: . . * .:. :: * :* :. * : . * * :. . : .* : : . : * .:. : :. : * . : : : . * * ", "identical_positions": 14, "similar_positions": 57, "identity": "4.96%" }, { "cls_id": "homologset.agr.MGI:1929282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83868-1", "uniprot_id": "TEBP_RAT", "id": "P83868-1", "name": "Prostaglandin E synthase 3", "aln": "------MQPASAKWYDR-------RDYVFIEFCVEDSKDVNVNFEKSKLTFSCLG----GSDNFKHLN-EIDLFHCIDPNDSKHKRTD--RSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDR-----FSEMMDHMGGDE-------DVDLPEVDG-----------------------------ADDDSQDSDDEKMPDLE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q7-1", "uniprot_id": "TEBP_MOUSE", "id": "Q9R0Q7-1", "name": "Prostaglandin E synthase 3", "aln": "------MQPASAKWYDR-------RDYVFIEFCVEDSKDVNVNFEKSKLTFSCLG----GSDNFKHLN-EIDLFHCIDPNDSKHKRTD--RSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDR-----FSEMMDHMGGDE-------DVDLPEVDG-----------------------------ADDDSQDSDDEKMPDLE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15185-1", "uniprot_id": "TEBP_HUMAN", "id": "Q15185-1", "name": "Prostaglandin E synthase 3", "aln": "------MQPASAKWYDR-------RDYVFIEFCVEDSKDVNVNFEKSKLTFSCLG----GSDNFKHLN-EIDLFHCIDPNDSKHKRTD--RSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDR-----FSEMMNNMGGDE-------DVDLPEVDG-----------------------------ADDDSQDSDDEKMPDLE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28707-1", "uniprot_id": "SBA1_YEAST", "id": "P28707-1", "name": "Co-chaperone protein SBA1", "aln": "--MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKPSYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESEYWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGG----AGGMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VH95-1", "uniprot_id": "TEBPH_DROME", "id": "Q9VH95-1", "name": "Cytosolic Prostaglandin E synthase", "aln": "MSAAAGLIPPPVSWAQR-------NDLIYVIIDV-ECKDIEHKVTEKTFTFKGVN----VLDPSKKYEVTLNFLHEVDPEKVTSKNIG--RCLEFTIPKKAAGPYWSSLTTDKTKLHFLKANFAKWRDESDDEEGDQKDNSM-----FGNFLNSPGGDWNNKFDDFNVDDEEEDS-------------------DDNIPSLSQNDEDDEEGGEGDKEKKPAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * :* .: : : . : :.. : .. . : :. . : :: : ::: : : *:. * . : : * . *. **.::.* ::..:* :* * .::.: : .. . *.:::. ** .:* : . ::*.:. : : . ", "identical_positions": 17, "similar_positions": 73, "identity": "7.66%" }, { "cls_id": "homologset.agr.MGI:1929285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FAH8-1", "uniprot_id": "F7FAH8_RAT", "id": "F7FAH8-1", "name": "Origin recognition complex subunit 6", "aln": "MESDLVRHLARRLGLGE-PSVLRKAEEYLRLSKVKCVSLSAHTSETSNAVICLDLAASCRKCPLDRAYLIKLSGLNKKMYQSCLKSFECLLGLNSNIGLRDLAVQFSCTEAVNLAAGILQSYESSLPEAQRADLDLSRPLFTTAALLSACKILKIKVDKTKMITTSGVKKTIFDRLCTQLEKIGQQINRDSADLASPALKKKKPAFSPALKKKKSGLEQPAKDIEVIETS-DKLPKDAGLTQDYEEWKRKILENAAKAQTAAVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUJ8-1", "uniprot_id": "ORC6_MOUSE", "id": "Q9WUJ8-1", "name": "Origin recognition complex subunit 6", "aln": "MESELVRRLAPRLGLAE-PSVLRKAEEFLRLSKVKCVSLSARSSETSNAVICLDLAASCRKCPLDRAYLIRLSGLNKMMYQSCLKSFECLLGLNSNVGIRDLAVQFSCTEAVNLAAEILQSYKSGLPETQRADLDLSRPLFTTAALLSACKILKIKVDKTKMITTSGVKKAILDRLCKQLEKIGQQINRDSADLARPALKRKKPEFSPTLKKKEPGLEPPAKEIEVIETL-HKLPKDEDLTQDYEEWKRKILENAAKAQTATAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5N6-1", "uniprot_id": "ORC6_HUMAN", "id": "Q9Y5N6-1", "name": "Origin recognition complex subunit 6", "aln": "MGSELIGRLAPRLGLAE-PDMLRKAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDLDLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPRKRKK-----------IVVEAPAKEMEKVEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y1B2-1", "uniprot_id": "ORC6_DROME", "id": "Q9Y1B2-1", "name": "Origin recognition complex subunit 6", "aln": "-MTTLIEQLITKMGLREEPNVLEKTTELVRLLELRSTNVPLQINEYGKIVLCADLASCMIGIAFDKEQALKLSGLRKSQYLNNKRMFEKLLDLNKLASVNDICVQLGLNEVARKAEELMTLFKG-VAATEDMGTDTSHPQYATMAVFQACRLLKKKVSKSKLMPFSNLRPSQFQLLEQQWERMIAKHHKESKVPSSTDMEGKLKE-----NQNENIKGHEAKKAHKPPPEDYEIWKARMLAKAQAKLKELEASQSHMDSQLLEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :* ::** * *.:*.*: * :** .::...:. : .* .. *:* ***:. .:*: ::****.* * . : ** **.**. .:.*:.**:. *... * :: ::. :. :: . * *:* ::: *::.**::** **.*.*::. *.:: : :: * * *:: : .::. : . : * **. . : * *:: : *. .:: . ", "identical_positions": 57, "similar_positions": 96, "identity": "21.59%" }, { "cls_id": "homologset.agr.MGI:1929286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V735-1", "uniprot_id": "AMOL2_RAT", "id": "G3V735-1", "name": "Angiomotin-like protein 2", "aln": "--------------------------MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGAGGTGSPQASLEIGAPEDSQVLQQATRQEPQGQEHQGGETHLAENRLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGSRLHGGDRDPRG-ASGGSRRQDEALRELRHGHVRSLSERLLQLSLERNGARVPSHMSSSHSFPQLARSQQGPQPR-GPPAEGPEPRGPPPQYPHAVMAQET-AAVNDPRYRPRSSPHFQHAEVRILQAQVPPVFLQQQQ-YQYLQQPQEHSPPLHPAALGHGPPSSFSPPALEGPPGAQA---TSGSAHLAQMESVLRENARLQRDNERLQRELESTSEKASCIEKLENEIQRLSEAHESLMRTSSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRHLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQSRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQTGTLTGGGGSHTGSTELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLAGNHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRKDPGKATQGTLRPAKSVPSIFAAAVG-TQGWQGFSTSERQ-TDAPARQTVDRGPAEEPPATPPLPAHTKHGSRDGSTQTDGPADSTSACLASEPDSLLGCNGSQRTTSLDSIAATRVQDLSDMVEILI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K371-1", "uniprot_id": "AMOL2_MOUSE", "id": "Q8K371-1", "name": "Angiomotin-like protein 2", "aln": "--------------------------MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGAGGTGSPQASLEIGAPEDSQVLQQATRQEPQGQEHQGGETHLAENRLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGSRPHVGDRDPRGGVSGGGRRQDEALRELRHGHVRSLSERLLQLSLERNGARVPSHMSSSHSFPQLARSQQGPQPR-GPPAEGPEPRGPPPQYPHAVMAQET-AAVTDPRYRPRSSPHFQHAEVRILQAQVPPVFLQQQQ-YQYLPQPQEHSPPLHPAALGHGPPSSFGPPAVEGPPSAQA---TLGSAHLAQMETVLRENARLQRDNERLQRELESTSEKAGRIEKLENEIQRLSEAHESLMRTSSKREALEKTMRNKMDGEMRRLQDFNRDLRERLESANRHLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRHAELLEQALGNAQSRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQTGTLAGGGGSHGGSAELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLPGNHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRKDPGKATQGTLRPAKSVPSIFAAAVG-TQGWQGLVSSERQ-TDA--RPAGDRVPAEEPPATAPLPAHTKHGSRDGSTQTDGPADNTSACLASEPDGLLGCNSSQRTPSLDSIAATRVQDLSDMVEILI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2J4-1", "uniprot_id": "AMOL2_HUMAN", "id": "Q9Y2J4-1", "name": "Angiomotin-like protein 2", "aln": "--------------------------MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGTGGTGSPQASLEILAPEDSQVLQQATRQEPQGQEHQGGENHLAENTLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGTRPHAGDRDPRG-APGGSRRQDEALRELRHGHVRSLSERLLQLSLERNGARAPSHMSSSHSFPQLARNQQGPPLR-GPPAEGPESRGPPPQYPHVVLAHETTTAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLQQQQQYQYLQQSQEHPPPPHPAALGHGPLSSLSPPAVEGPVSAQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGS-GGSPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPARLTTDRAPTEEPVVTAPPAAHAKHGSRDGSTQTEGPPDSTSTCLPPEPDSLLGCSSSQRAASLDSVATSRVQDLSDMVEILI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1YB07-1", "uniprot_id": "AML2A_DANRE", "id": "A1YB07-1", "name": "Angiomotin-like 2a", "aln": "--------------------------MRTAEESSGTVLHRLIQEQLRYGNPTDP-TLLAIQQQALRGGSSGGGAGSPRSSLESLTQEESLSPQLSARQEPQGQEHQG-DFQHSESPVCHLYQLHT--EELPTYEEAKAHSQYLAYQRGQIGLHQGSLESPG--GVGGAEQDDSMWDAKREHARSLSERLLQLSLERNCAHDNIPMSSSHSYPQLSNNHSDTVVN-EQSVHQPDQRGPPPEYPFMVR---------SPGYMLSHSQEHGHYYN-----EPPPAFHSQHY----------RLFPTQPQAPRHNGLPTLTPAGQDVNVGGYS-----IPANNFQMEQLIKE-------NERLKREVDSYSEKAARLQKLEQEIQRISEAYETLMKGSAKREALEKTMRNKLESEIKRLHDFNRDLRDRLETANKQRAAIEVEDKS--RHAFAKLVEQNEDHLRERERLEKETQHLRASGEEWKRRREALEQALITAQTRNRQLEEELRRKRAYVEKVERMQSALAQLQAACEKREALELRLRTRLEQELKSLRAQQWQAQTQHASPGS---YLDLNVSSLQQQLREREEQVLALEADITRWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRNSPNSSFNEDLPSPNHRHQEMENRIRALYAQLLEKDAIIKVMQQRSRREQGRPELQGLRPARSVPSINTVATASTTRAKGKSLSDDQ------TAVASLPPLPHLLAKIQCRDSSTQCDSEEPSCKAEPAD--VAVSAPEPS----TASSSESTSLKTTQISSAVEN-DMVEILI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8A5S6-1", "uniprot_id": "AML2B_DANRE", "id": "B8A5S6-1", "name": "Angiomotin-like 2b", "aln": "MPLTESAWNESVGWFSSDHKYSTSSNKMRGEEASGTVLHRLIQEQLRYGNPTDAHTLLAIQQQALRRG--GGAASSSQSSSESLSQDEPHSPQLSTRQEPQGQEHQV-DYQHSEN--YTTYPHHQ--EELPTYEQAKAHSQYLASQWCLPHRVCSLQDSVA---IQKPCEEQDSWDMKQGHVRSISDRLLHFSMESG------KMPCSASYPQINGYHANQHLQYNQQGLEYNKLAPYTEYPFSVEY--------ENGYK------------------APPPFHSQHN--------------RLPTPEVCHRLSTSPPAGREVNACSRS-----------QLEMLMNE-------NKRLRQELEGQTEKALKIQKLEQEIQRISEAYDTLMKGCAKREALEQALRNKLMAEIKRLQHSSVQAAKQAEAADQN------------QHAIEKLHLQNEEQKLRCACLEQEVQHLRNEAEKHQRRSEALESTLRSTQTRSQQLWTELQRKRAYVEKVERLQGALTQLQATCEKREGLEMRLRTRLEQELRSLRNQQRQPQPVGG-------TSHVSVYTLQENLREKEERILSLEADKIRWEQKYLEEKTMREFAMDAAATAAAQRDTTIINHSP----CHSFIEELPSTEYRNQEVENRIRSLYAQILEKDTVISILKQKLQHEQ-KGQLGALQPATADSSIISSHSTPAHTAQGKERSHFN------------DQAAGTLHSSHAPVEALAHTTDQTPHTEAKPK-----------------NIQKAPSAVDLFKGVDDVSAEAVEIFI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::***************** *:. *********** * *.:.*.::* * : ::. * ::********** : : :*. *******:******* * * . :. . ::: : :: *.**:*:***::*:* . *..* *:**: : . . : .* .:**. * . * ** * .*: * . .: *.. : . : *:* ::.* *:**::*::. :*** ::***.****:***:::* : .:******:::***: .*::**:. . : .: *:*::. :. . ** *. :: . **:* ** *. :*: * **.:* .:* * : **::*:********:* ** ****:***** **:**********::** ** *. . . .:.. *.::***:**::*:**** :******** :**:****************:*.*** ** * * . :*:**:*.*:: *:**:****::*.:::*: ::: : *:** : .*: : : :* *. : . : : .. . .. . ..:.* : ***:*", "identical_positions": 249, "similar_positions": 186, "identity": "30.82%" }, { "cls_id": "homologset.agr.MGI:1929288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET43-1", "uniprot_id": "CLD12_MOUSE", "id": "Q9ET43-1", "name": "Claudin-12", "aln": "MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRNEKNLTIYTGLWVKCARYDGSSDCLMYDRTWYLSVDQLDLRVLQFALPLSIVIAMGALLLCLIGMCNTAFNSSVPNIKLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWAIFYNSHLNRKFEPVFTFDYAVFVTIASSGGLFMTALLLFVWYCACKSLSSPFWQPLYSHAPGMHTYSQPYSSRSRLSAIEIDIPVVSHST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A8Y0-1", "uniprot_id": "D4A8Y0_RAT", "id": "D4A8Y0-1", "name": "Claudin-12", "aln": "MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRNEKNLTIYTGLWVKCARYDGSSDCLMYDRTWYLSVDQLDLRVLQFALPLSILIAMGALLLCLIGMCNTAFKSSVPNIKLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWAIFYNSHLNKKFEPVFTFDYAVFVTIASSGGLFMTALLLFVWYCACKSLSSPFWQPLYSHPPGMHTYSQPYSSRSRLSAIEIDIPVVSHST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56749-1", "uniprot_id": "CLD12_HUMAN", "id": "P56749-1", "name": "Claudin-12", "aln": "MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRNEKNLTVYTGLWVKCARYDGSSDCLMYDTTWYSSVDQLDLRVLQFALPLSMLIAMGALLLCLIGMCNTAFRSSVPNIKLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWVIFYNIHLNKKFEPVFSFDYAVYVTIASAGGLFMTSLILFIWYCTCKSLPSPFWQPLYSHPPSMHTYSQPYSARSRLSAIEIDIPVVSHTT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************:********************* *** *****************::******************.***************************************.**** ***:******:*****:*****:******:*:**:***:****.**********.*.*********:****************:*", "identical_positions": 223, "similar_positions": 18, "identity": "91.39%" }, { "cls_id": "homologset.agr.MGI:1929289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMB5-1", "uniprot_id": "ADRM1_RAT", "id": "Q9JMB5-1", "name": "Proteasomal ubiquitin receptor ADRM1", "aln": "MTTSGALFPSLVPGSRGSSTKYLVEFRAGKMSLKG--TTVTPDKRKGLVYIQQTDD---SLIHFCWK--DRTSGTVED--DLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNECLNNPPMPGTLGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPASSSSSSSRSQSAAVTPSS----TTSSARATPAPSAPAAASATSPSPAPSSGNGTST-----AASPTQPIQLSDLQSILATMNVPAGPGGSQQVDLASVLT-PEIMAPILANADVQERLLPYLPSGESLP-QTAEEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNN-----------AKSDPKEGDTKD----KKDEEEDMSLD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKV1-1", "uniprot_id": "ADRM1_MOUSE", "id": "Q9JKV1-1", "name": "Proteasomal ubiquitin receptor ADRM1", "aln": "MTTSGALFPSLVPGSRGSSTKYLVEFRAGKMSLKG--TTVTPDKRKGLVYIQQTDD---SLIHFCWK--DRTSGTVED--DLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNECLNNPPMPGSLGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPASSSSSSSRSQSAAVTPSS----STSSARATPAPSAPAAASATSPSPAPSSGNGTST-----AASPTQPIQLSDLQSILATMNVPAGPGGSQQVDLASVLT-PEIMAPILANADVQERLLPYLPSGESLP-QTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNN-----------AKSDPKEGDTKD----KKDEEEDMSLD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16186-1", "uniprot_id": "ADRM1_HUMAN", "id": "Q16186-1", "name": "Proteasomal ubiquitin receptor ADRM1", "aln": "MTTSGALFPSLVPGSRGASNKYLVEFRAGKMSLKG--TTVTPDKRKGLVYIQQTDD---SLIHFCWK--DRTSGNVED--DLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPGSSSSSSSRSQSAAVTPSS----TTSSTRATPAPSAPAAASATSPSPAPSSGNGAST-----AASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLT-PEIMAPILANADVQERLLPYLPSGESLP-QTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNN-----------AKPEQKEGDTKD----KKDEEEDMSLD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZ09-1", "uniprot_id": "ADRM1_DANRE", "id": "Q6NZ09-1", "name": "Proteasomal ubiquitin receptor ADRM1", "aln": "-MSSGALFPSLVSGSRSSSSKYLVEFRAGKMTLKG--STVTPDKRKGTVYIQQTDD---SLIHFCWK--DRTSGNVED--DLIIFPDDCEFKRVNQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDDEYCRKVNEYLNNPPMPGALGSGGGGGHELSALG-EGGLQSLLGNMSHNQLMQLIGPTGLG---GLGALAGPGLASLLGSGGPATSSSTSSSRSQSAAATPSSGSAARLSSTQAPTTPVTPAATSSGSPTVTPTTPAAQTPSLPAGPASSTQPIQLSDLQSILATMNVPAMPTEGSGVDLASVLT-PDVMAPILANPEVQQRLLPYLPSGESLP-QSAEEIQNTLTSPQFQQAMSMFSSALASGQLGPLMNQFGLPSEAVDAANKGDVEAFAKAMEG------------SDSKTDDGDSKD----KKDDDEDMSLD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K2G1-1", "uniprot_id": "ADRM1_DROME", "id": "Q7K2G1-1", "name": "Proteasomal ubiquitin receptor ADRM1 homolog", "aln": "------MFGRQSGLGSSSNSSNLVEFRAGRMNMVG--KMVHPDPRKGLVYMTQSDD---GLMHFCWK--DRTSGKVED--DLIVFPDDFEYKRVDQCKTGRVYVLKFKSSTRRMFFWMQEPKTDKDDEQCRRINELLNNPPSAHQRGGGGSN---------DGDLQYMLNNMSQQQLMQLFG--------GVGQMG--GLSSLLGQMNSRTPSSRNTSSSGGGGASALQ----TPENVSVPRTPSAPSKSGSSRSSSNVNSQVGEGAG---------------------SSVDADA-PGRSLNIDLSTALPGADAINQIIADPEHVKTLIVHLPESEDVDDDRKQQIKDNITSPQFQQALAQFSSALQSAQLGPVIKQFELSNEAVAAAFSGNLEDFVRALEKSLPPGATMGGKPSASEKKASDPETPTSVARDENTDPATEKQEEKQK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O13563-1", "uniprot_id": "RPN13_YEAST", "id": "O13563-1", "name": "26S proteasome regulatory subunit RPN13", "aln": "----------------MSMSSTVIKFRAGVCEYNEDSRLCTPIPVQGEIEIKPNEEEELGFWDFEWRPTEKPVGRELDPISLILIPGETMWVPIKSSKSGRIFALVFSS-NERYFFWLQEKNSGN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLNELSAKDKEIYNKMIGVLNNS-----------SESDEEESNDEK----QKAQDVDVSMQD------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :::**** * :* : : .:: .: .* *: ::. * * .**::*.: : : .. :**::.* *.: ..* ***:** ::.: *. : : * . : : .:: : .. . .: : : :: * : : ", "identical_positions": 26, "similar_positions": 62, "identity": "5.79%" }, { "cls_id": "homologset.agr.MGI:1929293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q568Z7-1", "uniprot_id": "CIB2_RAT", "id": "Q568Z7-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVP--MDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z309-1", "uniprot_id": "CIB2_MOUSE", "id": "Q9Z309-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVP--MDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLEMTLARLTKSELEEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75838-1", "uniprot_id": "CIB2_HUMAN", "id": "O75838-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVP--MDYRKSPIVHVPMSLIIQMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC72-1", "uniprot_id": "CIB2_DANRE", "id": "Q6PC72-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTDEQLDAYQDCTFFTRKEILRLHGRYHELAPHLVP--MDYTNDPDVKVPLALIVNMPELKENPFRNRIVESFSEDGQGNLSFNDFVDMFSVLSEMAPRELKAIYAFKIYDFNVDNYICKEDLEKTLNKLTKEELTPEEVNLVCEKAIEEADLDGDNKLSFADFENMISRAPDFLSTFHIRI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2Q5-1", "uniprot_id": "CIB2_DROME", "id": "Q9W2Q5-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKVVTFTEQELDDYQDCTFFTRKEILRVHKRFRELRPDLVPRQMTEGQASSVKVPCECIEKMPELRENPFRRRICEAFSRDGQGNLSFEDFLDALSVFSEQAPRDIKVFYAFKIYDFDQDGFIGHADLMSCLTTMTKNELSPEEHQQIADKVIEEADVDGDGKLSILEFEHVILRAPDFLSTFHIRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** . **:::** *******.:*:**::* *: ** *.*** * : . *:** * :****:****:.** :**.**:***:*:**:* :**:.* ***::*. ********: *.:* : ** * :**.** :* :.:*.*****:***.**.: :**.:* :************", "identical_positions": 103, "similar_positions": 49, "identity": "54.5%" }, { "cls_id": "homologset.agr.MGI:1929455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PC14-1", "uniprot_id": "RL23_DANRE", "id": "Q6PC14-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPSAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62830-1", "uniprot_id": "RL23_MOUSE", "id": "P62830-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62829-1", "uniprot_id": "RL23_HUMAN", "id": "P62829-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62832-1", "uniprot_id": "RL23_RAT", "id": "P62832-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y4M0-1", "uniprot_id": "A0A8I5Y4M0_RAT", "id": "A0A8I5Y4M0-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48159-1", "uniprot_id": "RL23_DROME", "id": "P48159-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGTAGGKFRISLGLPVGAVMNCADNTGAKNLYVIAVHGIRGRLNRLPAAGVGDMFVATVKKGKPELRKKVMPAVVIRQRKPFRRRDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNASSIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX41-1", "uniprot_id": "RL23A_YEAST", "id": "P0CX41-1", "name": "Large ribosomal subunit protein uL14A", "aln": "MSGN---GAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX42-1", "uniprot_id": "RL23B_YEAST", "id": "P0CX42-1", "name": "Large ribosomal subunit protein uL14B", "aln": "MSGN---GAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . *: * ******** ***::* **.:*::*:*:*:*: .**:***:*.:*.*.:***:*.:*:***** **:*:** *. *:*** :***::* **.* **:*********:.** ** ***:***:. .", "identical_positions": 79, "similar_positions": 39, "identity": "56.43%" }, { "cls_id": "homologset.agr.MGI:1929459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM13-1", "uniprot_id": "RABX5_MOUSE", "id": "Q9JM13-1", "name": "Rab5 GDP/GTP exchange factor", "aln": "------------------------MSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQRQIQEDWELAERLQREEEEAFASSQSSQGAQS---------LTFSKFEEKKTNEKTRKVTTVKKFFSASSRAGSKK----------------------------------------------------EIQEAKAPSPSINRQTSIETDRVTKEFIDFLKTFHKTGQEVYKQTKMFLEAMPYKR-DLSIEEQSECTQDFYQNVAERMQTRG---KVPPEKVEKIMDQIEKHIMTRLYKFVFCPETTDDEKKDLAIQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITRCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLS-QEDFDRYMSGQTSPRKQESES-WPPEACLG---VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAKEVQDIVEKYPLEIKPPNQPLAAIDSE--NVENDKLPPPLQPQVYAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ABA8-1", "uniprot_id": "A0A8I6ABA8_RAT", "id": "A0A8I6ABA8-1", "name": "Rab5 GDP/GTP exchange factor", "aln": "MGGGDAHPLSQNTGREPAWSIEKKMSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQRQIQEDWELAERLQREEEEAFASSQSSQGAQS---------LTFSKFEEKKTNEKTRKVTTVKKFFSASSRAGSKK----------------------------------------------------EIQEAKAPSPSINRQTSIETDRVTKEFIDFLKTFHKTGQEVYKQTKMFLEAMPYKR-DLSIEEQSECTQDFYQNVAERLQTRG---KVPPEKVEKMMDQIEKHIMTRLYKFVFCPETTDDEKKDLAIQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITRCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLS-QEDFDRYMSGQTSPRKQESES-WSPEACLG---VKQMYKNLDLLSQLNERQERIMTEAKKLEKDLIDWTDGIAKEVQDIVEKYPLEIKPPNQPLAAIDSE--NVENDKLPPPLQPQVYAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJ41-2", "uniprot_id": "RABX5_HUMAN", "id": "Q9UJ41-2", "name": "Rab5 GDP/GTP exchange factor", "aln": "------------------------MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQS---------LTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKK----------------------------------------------------EIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKR-DLSIEEQSECAQDFYHNVAERMQTRG---KVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLS-QEDFDRYMSGQTSPRKQEAES-WSPDACLG---VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSE--NVENDKLPPPLQPQVYAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWV2-1", "uniprot_id": "A0A8M3AWV2_DANRE", "id": "A0A8M3AWV2-1", "name": "", "aln": "------------------------MSQRSERRGIHVDQSELLCKKGCGYYGNAAWQGLCSKCWRDEYQKARQRQIQDDWALAEKLQREEEAAYVSSHSSSQTQPPQSHSQHSLATFSKFEEKKTNEKTRKVTTVKKFFSPSSRTAPKKVPPEKEREKEKEEKLPGRRESHGENLLRDLKGIFTQPWEMSSPTEALVSRLRESHEAKTPSPSITRQSSIETDRVSRDFVEFLKTLHKPGREIHKHSRAFIDSMGNKKQDLSAEELSECVQDFYQGMSDRLLNHF---KGSSEKVDRVMDQVEKYIMTRLYKSVFCPETSDDEKKDLATQHRIRALHWVTIQMLCVPVEEEIPEVSDSVVKAITDIIEMDSKRVPRDKLACITSCSKHIFNAIRVTKNEPASADDFLPTLIYIVLKANPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLS-PEDFERYMSGQASPRRQDDPAGWPQSGSRVNPVLTQIQHNLSVLSSLEKRQQQVIEGAQSLEAELTEWQESVAREVQEILERYPLDIKPR---ASAIDAE--NVENDRLPPPLQPQVFAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0H9-1", "uniprot_id": "Q9W0H9_DROME", "id": "Q9W0H9-1", "name": "", "aln": "------------------------MSTAARPPSLRLGQQDLKCRSGCGFYGTPQNEGLCSMCFREKFNDKQRKLKQTGGETGPGSSSSVATLDRRSPQHAHLQG---------KVEQQVRKPSDKEQDNLGTLQKKKFTAVLQKTLQAG-------------------------------------------------AQKITQQRGHVPDPTEGQFLLQLRQLRIPDDGKRKLKLEIQRLDSDIRKYMNGNGGKN----INELSDLVQNAYTKVSDIVHNDPSFEIATNEDRDSAIDFFEKVVMTQNHKFLFSPYFTTDEDSDVKVQKRIRQLSWITAKHLDCSIDEVNSEARDLVYNAISELVGIDSYYSPQEKLQCTWRCCRHIFELLKRATGGPASADDFLPALIFVVLKANPVRLHSNINFVTRFTNASRLMSGESGYYFTNLCSAIAFIENLNGESLGVS-SEEFEALMSGQQ-PYSTPWES--ALLACES---LHLISENMKRMEMLQKRNALISSGITSFEKELIDFQREVTERVDTVIAKAPLNLLPIKTPAFLIGQARAHLLNESEAGHYQANMLHGGSLTSQSLTAAGGLVKPAAASKESGLSLKDTSMSSMGRLSPLQQNVQPADHLFASPIFNYTAFDAVSLLEEPVPDANTDVLMLGSEFQGGLTNINYDFDLSDQSGENSTADESKLNLDEFDPLAQKGLVAKPPPPLPETSLLDSTTDSLIDSEVPGTAVLLPSPLKPEVSNYRGFSNFDIPSISCNTGDFSSLGQDGADAPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54787-1", "uniprot_id": "VPS9_YEAST", "id": "P54787-1", "name": "Vacuolar protein sorting-associated protein 9", "aln": "------------------------MTDDEKRE---------------------ILKEFDPFSQLEQANGNPDKDVKFKKDDPNRAAAEETNRDISAQDKGDEEP-----------FYDFQIFIKQLQTPGADPLVKYTKSFLRN-------------------------------------------------------------------------FLAQRLLWTVSEEIKLISDFKTFIYDKFTLYEPFRSLDN-----SKMRNAKEGMEKLIMGKLYSRC-----------------FSPSLYEILQKPLDDEHMKDLTNDDTLLEKIRHYRFISPIMLDIPDTMPNARLNKFVHLASKELGKINRFKSPRDKMVCVLNASKVIFGLLKHTKLEQNGADSFIPVLIYCILKGQVRYLVSNVNYIERFRSPD-FIRGEEEYYLSSLQAALNFIMNLTERSLTIEDHEDFEEAYQRNFKQLAEEKEEEEKKKQLEIP---DELQPNGTLLKPLDEVTNIVISKFNELFSPIGEPTQEEALKSEQSNKEEDVSSLIKKIEENERKDTLNTLQN--MFPDMDPSLIEDVCIAKKSRIG---------PCVDALLSLSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : : . . :: : : : . : . : ... : : * .. : : * : : : : .. : .. .: : :. : : . . : . : : * .* .:** ::: * . .. . * * .:: :: *::*: * ..: ** :: :. .**.*:*.**: :**.: * **:::: ** ... :: **. **::.* .*: ** :* .** :. *:*: . : : * :. *:: : .: : : : . : . :. : * :..: . ", "identical_positions": 44, "similar_positions": 124, "identity": "5.58%" }, { "cls_id": "homologset.agr.MGI:1929461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88917-1", "uniprot_id": "AGRL1_RAT", "id": "O88917-1", "name": "Adhesion G protein-coupled receptor L1", "aln": "MARLAAALWSLCVTTVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLAFPNPYQFVSSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPAPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIASELARHTRG-SIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLSTEGQVQELVFPQ---EYASESSIQLSANTIKQNSRNGVVKVVFILYNNLGLFLS---------------TENATVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEAKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHRE---IYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEVACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV----EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS-FIGPVSFVIVVNLVFLMVTLHKMIRSS--SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------KESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEY----------SKCLRHSYCCIRS----PPGGAHGSLKTSAMRSNTRYYTGTQVPGQGRHIHQVSLGPRGRSALPESQKDPGGQSGPGDPLTFGLCPSRIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREP--------------------------------------------KHPLG-GREACGMDTLPLN-------------GNFNNSYSLR----------SGDFPPGDGGPEPP-----RG-----------------RNLADAAAFEKMIISELVHNNLRGASGGAKGPPP----------------EPPVPPVPG-VSEDEAGGPGGADR--AEIELLYKALEEP--------------LLLPRAQSVLYQSDLDESESCTA------------EDGATSRPLSSPP---GRDSLYASGANLRDSPSYPDSSPEGPNEALPPPPPAPPGPPEIYYT--SRPPALVAR-NPLQGYYQVRRPSHEGYLAAPSLEGPGPDGDGQMQLVTSL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TR1-1", "uniprot_id": "AGRL1_MOUSE", "id": "Q80TR1-1", "name": "Adhesion G protein-coupled receptor L1", "aln": "MARLAAALWSLCVTTVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPY-----IFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLAFPNPYQFVSSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPAPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIASELARHTRG-SIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLNTEGQVQELVFPQ---EYPSENSIQLSANTIKQNSRNGVVKVVFILYNNLGLFLS---------------TENATVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEAKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHRE---IYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEVACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV----EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS-FIGPVSFVIVVNLVFLMVTLHKMIRSS--SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------KESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEY----------SKCLRHSYCCIRS----PPGGTHGSLKTSAMRSNTRYYTGTQS--------------------------------------------RIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREP--------------------------------------------KHPLG-GREACGMDTLPLN-------------GNFNNSYSLR----------SGDFPPGDGGPEPP-----RG-----------------RNLADAAAFEKMIISELVHNNLRGASGGAKGPPP----------------EPPVPPVPG-VSEDEAGGPGSADR--AEIELLYKALEEP--------------LLLPRAQSVLYQSDLDESESCTA------------EDGATSRPLSSPP---GRDSLYASGANLRDSPSYPDSSPEGPNEALPPPPPAPPGPPEIYYT--SRPPALVAR-NPLQGYYQVRRPSHEGYLAAPSLEGPGPDGDGQMQLVTSL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94910-1", "uniprot_id": "AGRL1_HUMAN", "id": "O94910-1", "name": "Adhesion G protein-coupled receptor L1", "aln": "MARLAAVLWNLCVTAVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLTFPNPYQFISSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIASELARHTRG-SIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQE--EYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLS---------------TENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHRE---IYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV----EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS-FIGPVSFVIVVNLVFLMVTLHKMIRSS--SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------KESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEY----------SKCLRHSYCCIRS----PPGGTHGSLKTSAMRSNTRYYTGTQS--------------------------------------------RIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREP--------------------------------------------KHPLG-GREACGMDTLPLN-------------GNFNNSYSLR----------SGDFPPGDGGPEPP-----RG-----------------RNLADAAAFEKMIISELVHNNLRGSSSAAKGPPPP---------------EPPVPPVPGGGGEEEAGGPGGADR--AEIELLYKALEEP--------------LLLPRAQSVLYQSDLDESESCTA------------EDGATSRPLSSPP---GRDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEIYYT--SRPPALVAR-NPLQGYYQVRRPSHEGYLAAPGLEGPGPDGDGQMQLVTSL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J3J7-1", "uniprot_id": "A0AC58J3J7_DANRE", "id": "A0AC58J3J7-1", "name": "", "aln": "MALALWILFTCTIALSHVRPSAQALSRSAMPFGLMRRELACEGYPIELRCPGSDVIMIETANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDVFPDPCPGTYKYLEIQYECVPYKVDQKVFVCPGTLLRVQAASLLQEAEHQSGAWCKDPLQSGDRLYVMPWTPYRTDMLYEYASWEDFKQNRATTTYKLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGEAIVNNANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEANNGRLVVSQVNPYTLRFEGTWETSFDKRLASNAFMACGVLYAVRSVYQDDDSEAGGDLVLYAYNTNRAREEPVHIPFPNPYQYVSSVDYNPRDNQLYVWNNYNVLRYPLEFGPPDPTAGPPVTTQMSSSTTTAARPITSTSLPSTIRPL---PPTAHPIGAINKA-PDLRPITATVPVTRRPLRVPPQGPEIEVCESRVARGVQWPATQKGETVDRPCPKGSLGIASFQCLSSPVLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIAAELVNHTQG-RIHAGDVSSSVRLIEQLLDILDAQLQALRPGNKESAARNYNKWQKRERTCRAYVQAVVQTVDNLLRAEALESWQDMNSTEQAHTATMLLDVMEKGAFLLANNMYN-NHFSDHAANVDLEVRVLNTETDSQDLSFPQ---SGPSDSSIQLSASTFKQYSRNGQVKVVFVLYKNLGSFLS---------------TENATVKMEMEAGIGGRG---LAVNSHVIAASINKESSRVFLTEPVVFTLRHLQLENHFSPNCSFWNYSERSMTGQWSSQGCRLIETNSTHTTCSCSHLTNFAVLMVHHEP--DYPGRMHELILFVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFIAELLFLIGIDKTQYHIACPIFAGLLHFFFLAAFSWMCLEGIQLYLMLV----EVFESEYSRKKYYYLCGYCFPALVVGISAAIDYRSYGTKKACWLRVDNYFIWS-FIGPVSFIIMLNLVFLMITLHKMIRNS--SALKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------ENTVIMAYLFTTFNAFQGMFIFIFHCALQKKVHKEY----------SKCLRHSYCCSRT----STTSSHGSLKNSALRTNNRYYTGSQTRHAAVHRQ-----------------------------------SRIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQTRTGSSPYNTLLAET--FTPPSPGVFNSTGTFRDP--------------------------------------------KSTLSKNRDHGGMETLPLN-------------GNFNNSYSLRSVGGSGAPGGSCDFLGGGGGDSPPPLLNPRGSETLGGIR---------RNLSDAAAFEKMIISELVHNNLRGGGGVGGGDRTCGSLARGHGHLGMGRAGGGVEPVIGMEDDEDFRSREARQRTPQDVELLYKALEEP--------------LLLQRAQSVLYQSDPDESESYTADLTESLGHSGHSAQSAAGQGHSGPPDSPARDSLYTSITNLRDSP-YPDSSPE-PLEVVPR--SAQP-PEELYYS--SGRPAIGSRGAPMQTFYQAP-PRRPSTEAHPAPEAPHSEGDGQMQLVTSL--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "---------------MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLS---NGPPIFGNGSGLIHPPGVG---------------------------AGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQ-----LHHHHNHHGEDTASPTKPSSKLPAGGNATSPSN---TRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCG----------------PTHARNLYWNMTRVGDVNVQPCP--GGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPT----------------------------WHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFP------------DQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGK-GRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDH----AWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMG-------------------ATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQ-PEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: .: :. : **** : :.* .*** : ***** . .**: . .*:* :*.::.::..** :: .* *:*.:. * ******:**** :*:*:. *.. * . . .*: .* * ... :**. . .*: * . ::* . : * :: . *:. : .*: * . : :: . ::*. ..* :* : * *. .: :. : * . .. .*.. * .: : .* .: * :.:. . :.:*: *: . :: . * . . .: . * .. :: *: . *.. . . ... * :: .* *:* ***::* * *:*:: :::. :. .** :: . * . ::.**: :.:::: : : : : ::: . ::** ::.**:* .*** . *.** *:*. :* :.** ** :* .*****:.: . . *: *.* **.*: ..: **: .. *:*. :: : *..* *::** :..* :*. :.* :. :.. * :**:**:**:.* . :: * :*: :*: **: :* ...* **** :: **::** * .:* **:.*:*.******:** : : : : :: ::.* *.:* :.*.: *: ::.* ::: *.:*:..: : *: *****:**::*: : * ::: :** :*:. :*:* *..: * *. : .: .: : *** .* :. **.*: .** :* :. * * * :::: *: ** ..:: : : ::: * *.* . . : :** .:: ::.:*:**. .*. . :::. . : : .* * **:: *::**:*** ::*:::** .**** * . : : *:* . : .: : * . .: : *: :*.:*:* :::.* **: * .. *:.* .::. : .. .* .* : . . :* * * . : ** ::.*.:* . .. ..** *. .* .:..*::* : . .. *... . * . .. ::: :. * *:.:: : * :::. : : :.*. . : .: :.* ..::: .: :.. : . . *:: * * :. * * * . : .. . . **. . ", "identical_positions": 273, "similar_positions": 483, "identity": "14.78%" }, { "cls_id": "homologset.agr.MGI:1929464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0P6-1", "uniprot_id": "SC11A_MOUSE", "id": "Q9R0P6-1", "name": "Signal peptidase complex catalytic subunit SEC11A", "aln": "-----MLSLD-FLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEK-KDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42667-1", "uniprot_id": "SC11A_RAT", "id": "P42667-1", "name": "Signal peptidase complex catalytic subunit SEC11A", "aln": "-----MLSLD-FLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMLITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEK-KDVVGRARGFVPYIGIVTILMNDYPKFSYAVLFLLGLFVLVHRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67812-1", "uniprot_id": "SC11A_HUMAN", "id": "P67812-1", "name": "Signal peptidase complex catalytic subunit SEC11A", "aln": "-----MLSLD-FLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEK-KDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97066-1", "uniprot_id": "O97066_DROME", "id": "O97066-1", "name": "Signal peptidase complex catalytic subunit SEC11", "aln": "MGVASMLQIDEMLGDFNRMNKRQSLYQVLSFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYKEEPVRVGEIVVFKVEGRDIPIVHRVIKLHEKEDGSVKFLTKGDNNNVDDRGLYAPNQLWLTK-KDIVGRARGFLPYVGIITIFMNEYPKVKWAILSILAIFVLLHRE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15367-1", "uniprot_id": "SEC11_YEAST", "id": "P15367-1", "name": "Signal peptidase complex catalytic subunit SEC11", "aln": "------------------MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNR-NTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * ::*.. ::.:** *:*:** : *.* ***************:***:*** * : :**::**:.:**::*******:: *::. . :******* :* .** : :* * *::** .:*:.* :* :** :.: .:*:* :*.: .*: *", "identical_positions": 73, "similar_positions": 53, "identity": "39.25%" }, { "cls_id": "homologset.agr.MGI:1929467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U204-1", "uniprot_id": "LTOR3_RAT", "id": "Q5U204-1", "name": "Ragulator complex protein LAMTOR3", "aln": "MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDSAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSNANTGLIVSLEKELAPLFEELIKVVEVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88653-1", "uniprot_id": "LTOR3_MOUSE", "id": "O88653-1", "name": "Ragulator complex protein LAMTOR3", "aln": "MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDSAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELIKVVEVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHA4-1", "uniprot_id": "LTOR3_HUMAN", "id": "Q9UHA4-1", "name": "Ragulator complex protein LAMTOR3", "aln": "MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELRQVVEVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503S6-1", "uniprot_id": "LTOR3_DANRE", "id": "Q503S6-1", "name": "Ragulator complex protein LAMTOR3", "aln": "MADNLRSYLYKQLPSVEGLHAIVVTDRDGAPVIKVANDNAPEYALRPAFLSTFALATDQGSKLGLSKNKSIICYYSTYQIVQFNRLPLVISFIASSNANTGLIFSLEKELVPLIEELRQVVEVA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJD2-1", "uniprot_id": "LTOR3_DROME", "id": "Q9VJD2-1", "name": "Ragulator complex protein LAMTOR3 homolog", "aln": "MSDDIKKYLDGLLQKVSGLYVIQITDRDGVPLLRVSQEKNVDFALMPSFIPTFTTACDQASKLGLGRNKTIISMYSNYQVVQMNKLPLILTFVGAENCNTGHILALEHQVDGYLEDIKQAVTEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*::: :* * .*.**:.* ::****.*:::*:::. :.** *.*:.**: * **.*****.:**:**. *..**:**:*:***:::*:.:...*** *.:**::: :*:: :.* :", "identical_positions": 50, "similar_positions": 55, "identity": "40.32%" }, { "cls_id": "homologset.agr.MGI:1929468", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97615-1", "uniprot_id": "THIOM_RAT", "id": "P97615-1", "name": "Thioredoxin, mitochondrial", "aln": "MAQRLLLRRFLTSVISRKPPQGVWASLTSTSLQTPPYNAGGLTGTPSPARTFHTTRVCSTTFNVQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKLIG------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97493-1", "uniprot_id": "THIOM_MOUSE", "id": "P97493-1", "name": "Thioredoxin, mitochondrial", "aln": "MAQRLLLGRFLTSVISRKPPQGVWASLTSKTLQTPQYNAGGLTVMPSPARTVHTTRVCLTTFNVQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKLIG------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99757-1", "uniprot_id": "THIOM_HUMAN", "id": "Q99757-1", "name": "Thioredoxin, mitochondrial", "aln": "MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W022-1", "uniprot_id": "Q9W022_DROME", "id": "Q9W022-1", "name": "Thioredoxin domain-containing protein", "aln": "------MQRQIINILG----------QTTRRLASGQQ-----------IRMLSVSAPRQEIFKVQSAEDFDKKVKNSQQPVIVDFFATWCNPCKLLTPRIESIVGEQAGSIKLAKVDIDEHSELALDYDVAAVPVLVVLQNGKEVQRMVGLQDEDKIRAWVAAAVKQAK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O76877-1", "uniprot_id": "O76877_DROME", "id": "O76877-1", "name": "Thioredoxin domain-containing protein", "aln": "-----MLKIAAEGIAPRLAAACCSIGAKSRGQRMAPQAARG------TQKYLSQSQHLHKMLVIKDHYEFDQKVINSDNPVIVNFHAEWCDPCKILTPKMLELLENSN-EIDLAVIDVETNLDLVETFEVKAVPAVLAFRNGVVVDKFIGLVDANSIETLIDKLKRKQQQKQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: .: : . : : ::. :*:.:* **: **:*:*.* **.***:* *:: .:: :. .: :* :*:: : :*. ::* ***.::.::** *::::*: * :.:.: : ", "identical_positions": 28, "similar_positions": 57, "identity": "16.28%" }, { "cls_id": "homologset.agr.MGI:1929469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K5E0-1", "uniprot_id": "LPAR3_RAT", "id": "Q8K5E0-1", "name": "Lysophosphatidic acid receptor 3", "aln": "MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWLLRQGLLDTSLTASLANLLVIAVERHMSIMRMRIHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVVVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCAPHDSNAERHPSRIPSTIHSRSDTGSQYLEDSISQGQVCNKSSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ31-1", "uniprot_id": "LPAR3_MOUSE", "id": "Q9EQ31-1", "name": "Lysophosphatidic acid receptor 3", "aln": "MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBY5-1", "uniprot_id": "LPAR3_HUMAN", "id": "Q9UBY5-1", "name": "Lysophosphatidic acid receptor 3", "aln": "MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQE-NPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:************.*:********************************.*********************************************:*******:******:*****************:****************************************************:*******:**:***.**:***:*********************:*********************************:**.*****************:*************.**:***** :: *.**:*** ***: ***:*****:******* ****. *", "identical_positions": 319, "similar_positions": 28, "identity": "90.11%" }, { "cls_id": "homologset.agr.MGI:1929470", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYP8-1", "uniprot_id": "A0ABK0LYP8_RAT", "id": "A0ABK0LYP8-1", "name": "Tyrosine-protein kinase", "aln": "--------------MVTSMPLCGRRAASEDSKADGTEAQPLVPTGRLMVLLHWPGPEGGEPWVTFSQPSLTAEEMCIHIAHKVGITPPCLNLFALYDAQAKVWLPPNHVLDTSQDATLRLYFRMRFYFRNWHGMNPQEPAVYRCGFPGAETSSDHAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHLCHLALNRGVPLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLRRVFRRFLQAFQPGHLSQQVVMVKYLATLERLAPRFGSEHIPVCHLEVLAQPERDPCYIQNSGQTTGDPGPELASGPATHEVLVTGTGGIQWRPLQTQDSER----GHSRGNPQGSQSGKKPKAPESGEHLAGSPQEPPWTYFCDFQDISHVVLK-ERRVHIHLQDN-KCLLLCLCSQAEALSFVALVDGYFRLTADSSHYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWPED---GLYLIQWSTSHLHRLILTVAHRNPASRNGPRGLRLRKFPITQQPGAFVLDGWGRSFDSLGDLRQALQGCSLRAGDDCFPLHHCCLPRPREISNLVIMRGSRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLSVGG---PNEGKVDSGCPSGPDRGSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHLAFLHGVCVRGSENIIVAEFVEHGPLDVWLRRQRGRVPMPWKMVVAQQLASALSYLEDKNLVHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLS-GGANSLGTATDMWGFGATLLEICFDGEAPLQGRGPS----EKERFYTKKHQLPEPSCPE-LATLTRQCLSYEPAQRPSFRTILRDLTRLQPQNLVGTSTVN--SDSPASDPTVFHKR------------------------YLKRIRDLGEGHFGKVSLYCYDPNN-DGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHS--VGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTYCDSSQSPPTKFIELIGVTQGQMTVLRLTELLERGERLPRPDRCPCEVSPDRCSPFPPSSQGKWPHSPISPADLSPHEELLGVRGLLPAHVPESCAHP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R117-1", "uniprot_id": "TYK2_MOUSE", "id": "Q9R117-1", "name": "Non-receptor tyrosine-protein kinase TYK2", "aln": "--------------MVGTMPLCGRRAILEDSKADGTEAQPLVPTGCLMVLLHWPGPEGGEPWVTFSQTSLTAEEVCIHIAHKVGITPPCLNLFALYNAQAKVWLPPNHILDTSQDMN--LYFRMRFYFRNWHGMNPQEPAVYRCGFPGAETSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHLCHLALSRGVPLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLRAFRPGHLSQQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDPCYIQNSGQTAGDPGPELPSGPPTHEVLVTGTGGIQWHPLQTQESER----GNSRGNPHGSRSGKKPKAPKAGEHLTESPQEPPWTYFCDFQDISHVVLK-ERRVHIHLQDN-KCLLLCLCSQAEALSFVALVDGYFRLTADSSHYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWPED---GLYLIQWSTSHLHRLILTVAHRNPAFSNGPRGLRLRKFPITQQPGAFVLDGWGRSFASLGDLRLALQGCSLRAGDDCFPLHHCCLPRPREISNLVIMRGSRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLRVGG---PDEGKVDNGCPPEPGGTSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGQVPMTWKMVVAQQLASALSYLEDKNLVHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLS-GGTSSLGTATDMWGFGATLLEICFDGEAPLQGRGPS----EKERFYTKKHQLPEPSSPE-LATLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGTSAVN--SDSPASDPTVFHKR------------------------YLKKIRDLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHC--VGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTYCDSNQSPHMKFTELIGHTQGQMTVLRLTELLERGERLPRPDRCPCEIYHLMKNCWETEASFRPTFQNLVPILQTAQEKYQG-------QVPSVFSVC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29597-1", "uniprot_id": "TYK2_HUMAN", "id": "P29597-1", "name": "Non-receptor tyrosine-protein kinase TYK2", "aln": "------------------MPLR-HWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLK-EHCVSIHRQDN-KCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP-DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN--PDSPASDPTVFHKR------------------------YLKKIRDLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG-------QAPSVFSVC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24592-1", "uniprot_id": "JAK_DROME", "id": "Q24592-1", "name": "Tyrosine-protein kinase hopscotch", "aln": "MALANGGEDRMDDSSSGRTSLADSASLTNSSLRSGTSSQSIHTNDGTIRVFNFTTGEFER-----FHPNMLCEEICNTMCRQLGIAPIAQLLYGIREHSTSRRPSPLVRLDLT-------------WCLPGERLNCQLVYCFRMRFRVPELDS-----QLELIDGRSHKFLYRQMRYDMR------TEQIPEIRYPEHKDKSTGLAVMDMLIDDQEQ--SEDQQAMRSIEKLYKLYLPPSLWRAHSFFVGSKIREVFR----SLKANSLSVERLKWHYVHQVSHLAPTYMTEQFTCTVQYLPNEEVARGSGPIGTSLAHSTSTLASSGSTNTLSTLTTNTNSVALGGSGKKAKRR---STSGGIDVYVRVFPHDSLEPGLKVARVTSEATLKWILVGAVEGIFMISKINDTSVRLEIVGLPKGYEMQFQTEKEMKSFISYLGIYIRLSSKWMQDLCHSYRTPSLEELSSLHCHGPIGGAYSLMKLHENGDKCGSYIVRECDREYNIYYIDINTKIMAKKTDQERCKTETFRIVRKDSQWKLS-YNNGEHVLNSLHEVAHIIQADS-PDRYRIPASKYDKP-PLLLLLLPKNLKAKKTDLQLSEAELQRRNPQ------IFNPRTDLQWYPDSISLSD-----DGMMFTMRGDWIQQSPVKDVSVTMKMLKSDGN--FMEFFRLAQTWSLIQSPQFLKLYGLTLADP-YTMVMEYSRYGPLNKFLHSMPN-VTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKY------DPNSYVLDAKISDPGYPRPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLLRQKNLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNT---MQVSTDFHREIGIMRTLSHPNIVKFK----YWAEKSHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNGDGDCVKISDFGLAQFANS-DGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVTLFEMFSRGEEP--------NLVPIQTSQEDFLNR---LQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITREVATKVTHPTDGHQSPPNQPTDAE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . ..* * :*.: . . ::::. . ...: .**:* :.:::**:* . *:.: : .:. .* *: . : . :* : :* .* .* ::*:* *.::*:.* :::: : .* . ..*::* *:*.:.: : . :: * . * * *. :. :::.*** ::.. ** : : :*: :.:*** : :*:.. : : . .:. : . .... * ..*.*.*..: : ... . : :.. . * . ...* : : * :. . * : : :. **:: :. *:**::. : ***. .* * ***: .: ** :. * *::: . . : : : * . . : ..* * :: . : *. :... : .* . : : * : : . :* *:: :. :* *:**: .::* . . :. * : * . : : . :* : ::: *.:*:*... : : *:. *. * :. :: ::*: : .. :* *: .:***: :*: . *.: : : : *. .: ***:::::*. : *: ::: .* : *. :. . .* * . ** . : : . . : *.*.:*: ** : *. . :*: : * : .* : : : : ::* *.: *: *. ::.. * . . . . :.* **:.: : . :*.**:*.* : .: * . * **:* *: * :.:::** *:*** * :*:*:* .*** ::***: **: ** . :. .:*: ** :*.:** ** *********:*:*:: ***.*****: . . . ** .:.. * *: **:**.:. :* *****:****:*::: :. :*: .* .*. *: **** ** ** : : . . : .. : *. : ", "identical_positions": 216, "similar_positions": 384, "identity": "17.17%" }, { "cls_id": "homologset.agr.MGI:1929471", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7U8-1", "uniprot_id": "D4A7U8_RAT", "id": "D4A7U8-1", "name": "", "aln": "MESEHSRSVKSPSTMPLSGTPAP-NKRRKSSKLIMELT---------GGGRESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLESAGQGFSYGK--GSSGGQAGASGSAGQYGSDR-HQQGSGFGAGGAGGPGGQAGGGAAPGTVGVGEPGSGDQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEHVDYSVDIG-IPLDGETEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK37-1", "uniprot_id": "MYOZ1_MOUSE", "id": "Q9JK37-1", "name": "Myozenin-1", "aln": "--------------MPLSGTPAP-NKRRKSSKLIMELT---------GGGRESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLETAGQGFSYGK--GSSGGQAGSSGSAGQYGSDR-HQQGSGFGAGGSGGPGGQAGGGGAPGTVGLGEPGSGDQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEHVDYNVDVG-IPLDGETEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP98-1", "uniprot_id": "MYOZ1_HUMAN", "id": "Q9NP98-1", "name": "Myozenin-1", "aln": "--------------MPLSGTPAP-NKKRKSSKLIMELT---------GGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGGSGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITVFKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIG-IPLDGETEEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1X3-1", "uniprot_id": "A0A8M6Z1X3_DANRE", "id": "A0A8M6Z1X3-1", "name": "", "aln": "--------------MPVTGTPDPTNKRKNPSKIITDFSNISQHADQEDENAEASELDLGTKIKTPKDVMLEELSLMKNKGSKMFKMRQQRVEKFIVS-------DENLLNLKNLVPSLGCEMTAP-------------------------------HEQSP-----NPEPPREEVDVAAEK----------------EKRRREYVKTYVSPWERAMKDDQELKETMQLKMPGPQIYKDLPKYKSFNRMALPFGGFEKASRLVTFEPPEIKKTNEEPQPVSLSQYNICCRPSFNRTPIGWTCNEEHGHIHMEMENIPFDGETDDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::*** * **:::.**:* ::: . . *:* *:**.**..*:*********:.*:******:** ****** . *..: ::::::*::* :: :. *. .. .. * :.. .. : :: .***:***:*** * : * : :.: . :********* *:*:**:****: :**: *::. .:*: * : *:. ********* * .. * . ::: **:****::*", "identical_positions": 100, "similar_positions": 85, "identity": "30.86%" }, { "cls_id": "homologset.agr.MGI:1929472", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32Q54-1", "uniprot_id": "Q32Q54_RAT", "id": "Q32Q54-1", "name": "", "aln": "---------MALLVRVLRKQTSISQWVPICSQLMSVSSTQSQRSKTLSSTSQWLQKNPSGMCVGSEQIVGMDTP-HSRKYHNTSKLSTARDSPQPVEEKVGPFTKIIEAMGFTGPLKYSKWKIKIAALRMYTSCVEKTDFEEFFLRCQMPDTFNSWFLITLLHVWMCLVRMKQEG----RTGKYMCRIIVHFMWEDVEQRG-RVMGVN-SYILKKNMALMTNNFYAAVLGYDEGILSDDHGLAAALWRTFFN-QKCEDPRQLELLVEYVRKQMQYLDSMN------GEDLLLTGEVRWRPLVEKNPQSILKPHAPTYNDEGL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWU6-1", "uniprot_id": "UQCC1_MOUSE", "id": "Q9CWU6-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 1", "aln": "---------MALLVRVLRNQTSISQWVPVCSQLVSVSPTQRQWS----STSQWLQKNQSRVCLGSEQTVGADTA-QNRKYHNTSKLLTTQDFPQPVEEKVGPFTKIIEAMGFTGPLKYSKWKIKIAALRMYTSCVEKTDFEEFFLRCQMPDTFNSWFLITLLHVWMCLVRMKQEG----RTGKYMCRIIVHFMWEDVEQRG-RVMGVN-SYILKKNMALMTNNFYAAILGYDEGILSDDHGLAAALWRTFFN-QKCEDPRQLELLVEYVRKQMQYLDSMN------GEDLLLTGEVRWRPLVEKNPQSILKPHAPTYNDEGL----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVA1-1", "uniprot_id": "UQCC1_HUMAN", "id": "Q9NVA1-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 1", "aln": "---------MALLVRVLRNQTSISQWVPVCSRLIPVSPTQGQGDRALSRTSQWPQMSQSRACGGSEQIPGIDIQ-LNRKYHTTRKLSTTKDSPQPVEEKVGAFTKIIEAMGFTGPLKYSKWKIKIAALRMYTSCVEKTDFEEFFLRCQMPDTFNSWFLITLLHVWMCLVRMKQEG----RSGKYMCRIIVHFMWEDVQQRG-RVMGVN-PYILKKNMILMTNHFYAAILGYDEGILSDDHGLAAALWRTFFN-RKCEDPRHLELLVEYVRKQIQYLDSMN------GEDLLLTGEVSWRPLVEKNPQSILKPHSPTYNDEGL----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRZ7-1", "uniprot_id": "UQCC1_DROME", "id": "Q9VRZ7-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 1", "aln": "--------------------MQCTRAVARLAGGLARTAWATQHTYKHRPAILGLLEQPCRLCSST----GVVDN-TNKTKPGTAEAAEG-----------GILKRVLNKVGFT---PNTKARLKVTSHLLYESVADKINYVTFFRDFNLPNTFNSWFLVTELHVWLLLMRSMAEGSETGEDGRFLRNCIVEAMWGDVNTRA-KKLGAHNPSRTRQQIETLSEQFQAALIAYDEGIMSDDRVLACALWRRFFE-MNCDDYAQIERLVKYVRQQASMLDSLP------RDQFIVKPKVAWLELDKCKV--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21560-1", "uniprot_id": "CBP3_YEAST", "id": "P21560-1", "name": "Protein CBP3, mitochondrial", "aln": "MMSVNRFTSGRLPVFLRKSPFYYSRAYLHQTCVFKQNKETAQDSPELLAKSSHLNSKPLDVSNKAPVKTAQNKIPLAHSKYESSKYELPKWKEALGELVIRAFHLDMDRVRAGPVAGSYYYKICKEQGLQYEDEPLSETAKYFYEDLKLPRTFSQWFQITVLHEWILFVRMRAMP---FKYGRNYQQKLVDRTFSDIELRLFEEMKVNSGRIADQYLKDFNTQLRGAIFAYDEGFATDDGTLATAVWRNLFGGRKNIDMVHLESVVRYIYSQLYVLSRLSDREFATGKFKFVPPGVKVEKLTPKQEEELKAKTIAKYEALDKDPKTLPSERSRLSYTN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . . * . . : . :. : : : :: : :: * . . *: ::* **..** :* ** *: ::* . *: . :*. : *:: * . : .: : : :. :: .*::.****: :** ** *:** :* : * ::* :*.*: .* *. : . :: * * : ", "identical_positions": 38, "similar_positions": 69, "identity": "11.24%" }, { "cls_id": "homologset.agr.MGI:1929473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG87-1", "uniprot_id": "D3ZG87_RAT", "id": "D3ZG87-1", "name": "RPE-retinal G protein-coupled receptor", "aln": "MTATRALPAGFGELEVLAIGIVLLMEALSGISLNGLTIFSFCKTPDLRTPSNLLVLSLALADTGISLNALVAAVSSLLRRWPHGSEGCRVHGFQGFATALASICGSAAIAWGRYHHYCTRRQLAWDTAIPLVLFVWLSSAFWASLPLMGWGHYDYEPVGTCCTLDYSRGDRNFISFLFTMAFFNFLVPLFITHTSYRFMEQKLSRSGHLQVNTTLPGRMLLLGWGPYALLYLYAAVADVSFISPKLQMVPALIAKTMPTINAINYALRSEMVCRGTWQCRSAQKSKQDRTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2B3-1", "uniprot_id": "RGR_MOUSE", "id": "Q9Z2B3-1", "name": "RPE-retinal G protein-coupled receptor", "aln": "MAATRALPAGLGELEVLAVGTVLLMEALSGISLNGLTIFSFCKTPDLRTPSNLLVLSLALADTGISLNALVAAVSSLLRRWPHGSEGCQVHGFQGFATALASICGSAAVAWGRYHHYCTRRQLAWDTAIPLVLFVWMSSAFWASLPLMGWGHYDYEPVGTCCTLDYSRGDRNFISFLFTMAFFNFLVPLFITHTSYRFMEQKFSRSGHLPVNTTLPGRMLLLGWGPYALLYLYAAIADVSFISPKLQMVPALIAKTMPTINAINYALHREMVCRGTWQCLSPQKSKKDRTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47804-1", "uniprot_id": "RGR_HUMAN", "id": "P47804-1", "name": "RPE-retinal G protein-coupled receptor", "aln": "MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ***:*:*******:* ***:*****:*** **********:****.:**********:**********.********:**:**:.******.*******.***:*********** ****::*:.******:******:***:*********:*********:***** ******:**** :***** *** :****:.:**** ******.* *********:*****.:***: ************** :********** ****** *** *.** ::***:", "identical_positions": 230, "similar_positions": 43, "identity": "79.04%" }, { "cls_id": "homologset.agr.MGI:1929475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESJ7-1", "uniprot_id": "IKBP1_MOUSE", "id": "Q9ESJ7-1", "name": "Interleukin-1 receptor-associated kinase 1-binding protein 1", "aln": "MSLQPAPASRVFMELVPWADRGRENHPISAAEAQPIGRRP-HVAEAHPGAREVHVSGAAEVSASPDRALVTVRVSSTKEVSAEAKKSVCRRLDYITQSLQQQGFQAENVTVTKNIRRVENAYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPEFYHTPGSVENLRRQACLVAVENAWRKAQEVCDLVGQTLGKPLLIKEEETKDWEGQTDDHQLSRLPGTLTVQQKIKSATIHAASKVFITFEVKGKEKKKKHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VVH5-1", "uniprot_id": "IKBP1_HUMAN", "id": "Q5VVH5-1", "name": "Interleukin-1 receptor-associated kinase 1-binding protein 1", "aln": "MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSEVSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVENAYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEVKGKEKRKKHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q501X6-1", "uniprot_id": "IKBP1_DANRE", "id": "Q501X6-1", "name": "Interleukin-1 receptor-associated kinase 1-binding protein 1 homolog", "aln": "---MAHSPSRVFAALSPSAGDVYRDENQS---VFNRGRKQ-THLSAQSNVRVIEVTGCAEISSPPDRACVSISVKNSKENVNDVTNSVTRRLEYILQTARQHDVKEENITVTKHLQRDEDLFHMQAEVLVVFLDFEKMQQARTVLIEKLDKSVCVGDPYYSHSAESLSLLRRRVCLEAVDNARLKASEACCTLGQALGRPLLVREEESREWSSSQQDASGS----PLTLHPRTDATLISATSRMFVTFELRPKDNNRRKF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:*** * * *. .:. * . *: .*:. .* :.*:* :*:*: **** * : *..:** :..:** ***:** *: :*:..: **:****.::* *: :**:*** :.* :* ***: ..*:****.** :. * : *:. *:. ***:.** **:** **.*.* :**:**:***::***:::*... :* . * .**:: : .:: * *:*::*:***:: *::.::::", "identical_positions": 95, "similar_positions": 94, "identity": "36.54%" }, { "cls_id": "homologset.agr.MGI:1929480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQH7-1", "uniprot_id": "LRP10_MOUSE", "id": "Q7TQH7-1", "name": "Low-density lipoprotein receptor-related protein 10", "aln": "MLSALP-LLFLLLGGALARPDRITFPRSACEAPPAVLSEVQGTLQRPLGRDSRSSPANCTWVILGSKDQTVTVR-------------------------FQKLHLACGSEHLILHSPLQPPISLCEAP-SGPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDG-IDACGD----GSDEAGCSSD------------PFPNL--------NPAPAPTL----------ACNLTLEDFYGVFSSPGYSHLASVSHPQSCLWLLDPHDGRRLAVRFTALDLSYGDAVHVYDGAGPPETPRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSSGRGFNATYHVRGYCLPWDRPCGLGSGLGASENLGERCYSEAQRCDGSWDCAD-GTDEEGCPGCPPGHFPCGAAGTPGA------TACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDGSDEWDCSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSIRRLVRRLRRWGLLPRTNTPARAPETRSQVTP-SVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKTPIPTPSTLPALATVSEPPGPLPSVPVESSLLSGVVQVLRGRLLPSLW---------------SPGPTWTQTGTHTTVLSPEDEDDVLLLPLAEPEVWVVEAEDEPLLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F3K1-1", "uniprot_id": "F7F3K1_RAT", "id": "F7F3K1-1", "name": "Low-density lipoprotein receptor-related protein 10", "aln": "MLSALPFLLLLLLGGALARPDRIPFLNSACEAPPAVLLEVQGTLQRPLGRDSRSSPANCTWVILGSKEQTVTVRDLSSRGKVVSQSPDHRMSCSCVPGRFQKLHLACGSEHLILHSPLQPPVSLCEAP-AGPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDG-IDACGD----GSDEAGCRSD------------PFP----------NPVPAPTP----------PCNLTLEDFYGVFSSPGYSHLASVSHPQSCLWLLDPHDGRRLAVRFTALDLSYGDAVHVYDGAGPPETPRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGSGLGASENLGERCYSEAQRCDGSWDCAD-GTDEEGCPGCPPGHYPCGAAGTPGA------TACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDGSDEWDCSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSVRRLVRRLRRWGLLPRTNTPARAPETRSQATP-SVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKSPIPTPSTLPALATASEPPGPLPSVPVESSLLSGVVQVLRGRLLPSLW---------------PPGPTWTPTGTHTAVLPLEDEDDVLLMPLAEPEVWVVEAEDEPLLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z4F1-1", "uniprot_id": "LRP10_HUMAN", "id": "Q7Z4F1-1", "name": "Low-density lipoprotein receptor-related protein 10", "aln": "--MLLATLLLLLLGGALAHPDRIIFPNHACEDPPAVLLEVQGTLQRPLVRDSRTSPANCTWLILGSKEQTVTIR-------------------------FQKLHLACGSERLTLRSPLQPLISLCEAP-PSPLQLPGGNVTITYSYAGARAPMGQGFLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDG-VDACGD----GSDEAGCSSD------------PFPGL--------TPRPVPSL----------PCNVTLEDFYGVFSSPGYTHLASVSHPQSCHWLLDPHDGRRLAVRFTALDLGFGDAVHVYDGPGPPESSRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGSGLGAGEGLGERCYSEAQRCDGSWDCAD-GTDEEDCPGCPPGHFPCGAAGTSGA------TACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCSYVLPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGGPGARRRQRGRLMRRLVRRLRRWGLLPRTNTPARASEARSQVTPSAAPLEALDGGTGPAREGGAVGGQDGEQAPPLPIKAPLPSASTSPAPTTVPEAPGPLPSLPLEPSLLSGVVQALRGRLLPSLG---------------PPGPTRSPPGPHTAVLALEDEDDVLLVPLAEPGVWVAEAEDEPLLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCU1-1", "uniprot_id": "E7FCU1_DANRE", "id": "E7FCU1-1", "name": "", "aln": "MSVLHSLCFLGLLFLTVPCTLKLVFSAALCDHSPKILQSRQGEIHNSPYHSWPYHTLNCSWLITSKVGERVIIS-------------------------FSQFNMRCGRQWVSVVPLTGSPFKLCGSQLPAPFEMTGGNITVTHHFIPHIFPV-TGFRLSYFKDSGPCFPGEFECYSERCLPASWRCNGRVECLGVGDELGSDEDGCYSPEPPIDNSLNDLPPFETTTSTISLLSTDAPPPKIPDFPLLPQGGPCGGYLKAFYGSFTPP-----VPTGQKMECVWTVDPQDSRPLKLELQQLDLGVKDLITITD--QPYGMGNIIKTITFVSNNKAVEVESRTGLLSLIYRREPVLEGRGFNATYRITDYCLPWEELCG-GS-LGG-------CYTADQRCDGHWDCPETGLDEEACWGCKAGSFLCAMGGIKKAGHQTENPVCYSFHERCNYQLNCPDGTDERECTICQPGTFHCDSDRCVFESWRCDGQVDCKDGTDELNCTATLPRKVITAATVGSLVCGLLLVIAMGCTCKLYSLRTREYSLFAPITRQEAELIQQQAPPSYGQLIAQGIIPPVEDFPTENPNETVSLS-LRGILQLLRQDN----ASSLRRRRRPRFVRRAVRRLRRWGLIPRATSRPTQTTASSSQQTEAANSSTQPSQSSPGASSVATEAFSQSLTQKLGLSQQTETQQQAEAPPPSPSPPPPFPFQPVESAEAQQTPPITAPPSSPSLASLFHTLGRSISRFRPSPSTTSLPLSASPSFSSSSSEDEVLLIPLSDD---TTSEDDVPMLT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: ** ::. . :: * *: .* :* . ** ::.. :. . **:*:* .. : * : *.:::: ** : : : . . ..** : ..*:::.***:*:*: : *: ** *:* :* *: **:* ..**:.* **:* ::. * **** ** * ** . * *. .*. *: *** *:.* ....: .* * :**:*.* * :.: ***. * : : * * .:::::*..**.*** **: :* : *: . .********:: .*****:. ** ** **. **: ***** ***.: * *** * ** .* : *. .* * ..** :***** *.**:***.* ****.*:* .::**:*:* **** ** **:** :*: .*********.:************:*******::**:***:***::* ***::*************** *************:. *. **.:**:**** .. ***:* * :** *********:**:.: . . : *. . :. .: . :. . .. *. . . . : * :. : . * .. ...* *:* *:*.: . . *** .*..* .. .:. . ..**:***:**:: ... :* *:*:", "identical_positions": 276, "similar_positions": 210, "identity": "34.59%" }, { "cls_id": "homologset.agr.MGI:1929481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VCA2-1", "uniprot_id": "ORCT_DROME", "id": "Q9VCA2-1", "name": "Organic cation transporter protein", "aln": "-----------------------------------MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYEN-GSIYELSPHLWNLSYP-----EN----ERCSYYDVD------YTEEYLNGSIPRSS-------NETKTCSSYVYDRSKYLNSAVTEWNLVC-SRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSY-RLFAGVAMQMFFSVGFMLTA-------GFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVD------EVAEKKKQDEMAASQPAA-------------TVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQ----------------LVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDM-------------------NWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLK------------LLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKPAPQETAEEG------------GTQELSG--MLNGKSG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q95R48-1", "uniprot_id": "OCTL_DROME", "id": "Q95R48-1", "name": "Organic cation transporter-like protein", "aln": "-----------------------------------MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFEN-GSSYDLPTHLWNLSYP-----EN----ERCSYYDVD------YTEEYLNGSIPRSS-------NETKTCSSYVYDRSKYLNSAVTEWNLVC-GRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDK-RLYAGIFVMMFFSVGFMLTA-------VFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDEGPPP-------------SVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNV----------------LLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRM-------------------HTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLN------------FLATIWKPLPLLICGSLTLVAGLLSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEAQPLKGSGETNGSTIANGHK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O76082-1", "uniprot_id": "S22A5_HUMAN", "id": "O76082-1", "name": "Organic cation/carnitine transporter 2", "aln": "----------------------------------MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAA-NLSSAWRNHTVPLRLR-----DGREVPHSCRRYRLA------TIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTIVTEWNLVC-EDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLP-------LFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSE-------------LQDLSSKKQQSH-------------NILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDI----------------FVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDL-------------------YYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV------------YLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTRMLKD-------GQERPTILKS--TAF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70594-1", "uniprot_id": "S22A5_RAT", "id": "O70594-1", "name": "Organic cation/carnitine transporter 2", "aln": "----------------------------------MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTV-NLSSAWRNHSIPLETK-----DGRQVPQSCRRYRLA------TIANFSALGLEPGRDVDLEQLEQENCLDGWEYNKDVFLSTIVTEWDLVC-KDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLP-------LFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSE-------------LQDLNSKKPQSH-------------HIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDI----------------YVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISAALFLGGSVLLFIQLVPSEL-------------------FYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV------------YLGAYDRFLPYILMGSLTILTAILTLFFPESFGAPLPDTIDQMLRVKGIKQWQIQSQTRTQKD-------GGESPTVLKS--TAF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTN6-1", "uniprot_id": "S22AL_MOUSE", "id": "Q9WTN6-1", "name": "Solute carrier family 22 member 21", "aln": "----------------------------------MLDYDEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTV-NLSSAWRNHSIPMETK-----DGPEVPQKCRRYRLA------TIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIFLSTIVTEWDLVC-KDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLP-------LFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSET----------NKLQDDSSKKPQSH-------------HIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNI----------------YVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDL-------------------HYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV------------YLGAYDRRLPYILMGSLTILTAIITLFFPESSGVSLPETIDEMQKVKKLKQRQSLSKKGSPKESK-----GNVSRTSRTSEPKGF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VNX2-1", "uniprot_id": "Q9VNX2_DROME", "id": "Q9VNX2-1", "name": "", "aln": "-----------MAASEAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECD-LPGSNYYEPHTNWSIP-----KNGKDLDSCNRYTN------SELPQWN-HSVDICSADHFTKNKEACAHNEFVFRDD--EVTISNDFGIFC-DDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKR-RVLACSVITVFYAVGEVLLA-------MSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVL----------ANRDKLQ-QSSESR------------FPIREAFKNFKWR--IANCSLCWIVHVLVYYGLSLNVVLLDGDK----------------YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQ-------------------PVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTP------------LLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKDLDLVVTATQAQ--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNW8-1", "uniprot_id": "Q9VNW8_DROME", "id": "Q9VNW8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MTSQKEGNGYRRSDSKTTGHADAEAATQTAGGDEDNSLDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCD-SPSSVYEEDWLGFTIP-----KKNSAWDDCHRYAAN---ISDAISGYTDPSGQYCLKEYFTITSETCGR-DFKFRDE--EKTISTEFGIYC-EDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKR-RVAAATIITIFYALGEAFLG-------FLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLT----------SNRQKLS-QANESQ------------YPIMRAVVFFSLR--IANCCLCWFTHTLIALGLSLNSVNLGGNK----------------YTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADN-------------------YAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTP------------LLAKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEARDLNQAKRRSERSP------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFK6-1", "uniprot_id": "A0A0B4KFK6_DROME", "id": "A0A0B4KFK6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------MSAPAAGAASAVLDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQ--FVYGSS--ERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRK-REMSSIVLNYFYAVGEALLG-------LSV-FLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMASFKQ----------QELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNK----------------YLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVP------------LLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAIALGK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25297-1", "uniprot_id": "PHO84_YEAST", "id": "P25297-1", "name": "Inorganic phosphate transporter PHO84", "aln": "----------------------------------MSSVNKDTIHVAERSLHKEH----LTEGGNMAFHNHLNDFAHIEDPLERRRLALESIDDEGFGWQQVKTISIAG-----VGFLTDSYDIFAIN---------------LGITMMSYVYWHGSMPGPSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSPAIN---FVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAING-----LERASTAVESLDNHPPKAS-----------FKDFCRHFGQWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAGSKNVYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIGFAYHKLG-----------------DHGLLALYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTALGTLIDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEEINELYHDEIDPATLNFRNKNNDIESSSPSQLQHEA--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: . .: : : . * : : . . : ::.: : .. : .:. . . .. .: . :.. : . : : : . ** * : :*** *: : . .. : . : . * . *** : : * .:*. . . : *: :. : : . : ..* ** *. . : .:...::: : . : : :* :**: : ", "identical_positions": 22, "similar_positions": 90, "identity": "3.17%" }, { "cls_id": "homologset.agr.MGI:1929485", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V7D6-1", "uniprot_id": "NIF3L_RAT", "id": "Q4V7D6-1", "name": "NIF3-like protein 1", "aln": "MLSS--------AHVVPTSVRRAPSWICSSSRS-------------------------------------------------------FMDLKALLSSLNDFASLSFAES-WDNVGLLVEPSPPHT-------VNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHIT-WKTWKERLVIRALENRVAIYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSKAPNYPTEGTHRLEFSANHSQDLDKVMSAVKGVGGVSVTSFPARCDGEEQTRVSLNCTQKALMQVLAFLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIERIKRHLKLPHLRLALGVG--RTLESPVKVVALCAGSGGSVLQG--VEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSDLQEMLGVHLENKINIILSETDRDPLRVV--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ80-1", "uniprot_id": "NIF3L_MOUSE", "id": "Q9EQ80-1", "name": "NIF3-like protein 1", "aln": "MLSS--------AHLVPTSVQRAQSWICRSSRS-------------------------------------------------------FMDLKALLSSLNDFASLSFAES-WDNVGLLVEPSPPHT-------VNTLFLTNDLTEEVMDEALQKKADFILSYHPPIFRPMKHIT-WKTWKECLVIRALENRVAVYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSRAPDYPTEGAHRLEFSVNRSQDLDKVMSTLRGVGGVSVTSFPARCDGEEQTRISLNCTQKTLMQVLAFLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLAIMIERIKTHLKLSHLRLALGVG--RTLESQVKVVALCAGSGGSVLQG--VEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSELQEMLGVHFENKINIILSETDRDPLRVV--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZT8-1", "uniprot_id": "NIF3L_HUMAN", "id": "Q9GZT8-1", "name": "NIF3-like protein 1", "aln": "MLSSC-------VRPVPTTVRFVDSLICNSSRS-------------------------------------------------------FMDLKALLSSLNDFASLSFAES-WDNVGLLVEPSPPHT-------VNTLFLTNDLTEEVMEEVLQKKADLILSYHPPIFRPMKRIT-WNTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGACTSRPIHPSKAPNYPTEGNHRVEFNVNYTQDLDKVMSAVKGIDGVSVTSFSARTGNEEQTRINLNCTQKALMQVVDFLSRNKQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIDRIKRHLKLSHIRLALGVG--RTLESQVKVVALCAGSGSSVLQG--VEADLYLTGEMSHHDTLDAASQGINVILCEHSNTERGFLSDLRDMLDSHLENKINIILSETDRDPLQVV--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NK57-1", "uniprot_id": "NIF3L_DROME", "id": "Q9NK57-1", "name": "NIF3-like protein 1", "aln": "MLRR------------------------MNTFS-------------------------------------------------------GQKLAAVVKELENFAPTSWAEK-WDNVGLLIEPHREKQ-------IKKILLTNDLTEPVVKEALEKEAELIISYHPPIFKPLTRIT-QSHWKERVVAACLANDIALYSPHTAWDKKSGGVNDWLSKAVNIISIRPLEPELGAPPG-------------------------------------------------------------------------------------TGSGR--YIETKMELSQVVESLQKRIRNS-VHVALAVG--HTPKTLIQSVGICAGSGASLLKG--IQADLIITGEMSHHEVLEFTHNNTTVLLCNHSNSERGFLHEFCPILAKSLNEECLVFVSEVDKDPLVTVASDINKELSAFVDVYKSTSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AC58GW82-1", "uniprot_id": "A0AC58GW82_DANRE", "id": "A0AC58GW82-1", "name": "NIF3-like protein 1", "aln": "MLARCGQLSGKLLRLSRINFSISKTRTFISSLSSCHFSSPRSVFTSFFAYSALPRFSLHHSHLSASCYPALSSDRTIRFLSASTRPAEHMDLKGVLEVLEQLAPLSLAES-WDNVGLLVEPSRPRP-------IKTILLTNDLTAAVMDEAVGMKCDLIVSYHPPLFRPFKRLL-QKDWKQRLAVRAIENGIGIFSPHTSWDSVEGGVNDWLVGGMGRGKVSVLSQAVSSGAQK---HRIEFSCMDDGEVNSLLEQLRHTEGSETFQCTRIKSESGGQQVNLTCRSSALTGAVQILLSHPHTSKSLNITQVQQPPLLGCGQGRLSVLEEPVSVSTAVQKMKTHLGLPHLRLALGDQ--QTLDSMVKTVAVCAGSGASVIQG--VTADLYITGEMSHHEVLDAVSKGTSVILSEHSNSERGFLGVFRERLSARLDHTF------VQGNFCSVCE-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53081-1", "uniprot_id": "NIF3_YEAST", "id": "P53081-1", "name": "NGG1-interacting factor 3", "aln": "MSRAIT----------------------------------------------------------------------------------RAQLDKLVRSITKFYPQKYADKSWDNTGLLIDCSTAQVTTADANAKTKVLLTVDLTKSVAQEAVDANCNVIVAYHPFIFPSWNRLSPHTNPQHETAIKLIQYGISVYCPHTAVDAARGGVNDWLVRGLNNGENVAKSYALETVSG--------------------------------------------------------------------------------ETDDLIGYGRFVEFNKDISLEQIVKNVKRVLRVPYVQVASLAAPSAWNQLKIKKVAVCAGSGSGVFKQLKEDVDLYYTGEMSHHEVLKWKEMGKTVIVCNHSNTERGFLQDVMKGLLQ--DEGHEVVVSKMDCDPLTVA--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* :: : .: . . *:. ***.***:: : ..::** *** * .*.: :.:.*::*** :* . .:: . :. . : :.::.***: * ***.** .:. . * ** :: :.: :. :: : . :::* . :: *.:*****..::: .** *******:.*. . .*::.:***:***** . * :. : : . ", "identical_positions": 60, "similar_positions": 89, "identity": "12.71%" }, { "cls_id": "homologset.agr.MGI:1929492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L7Q4-1", "uniprot_id": "A0ABK0L7Q4_RAT", "id": "A0ABK0L7Q4-1", "name": "", "aln": "MAEGDEAARRQQPQQGLRRRRQTSDSSVGVNHVSSTTSLGEDYEDADLVNSDEVMRKPCPVQIVLAHEDDHNFELDEEALERILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNK----DSQSWIGGSNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDAYCRSMEQVCGGDKPYIAPSDLERKHLDLKEVALKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQVAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLT-DQVSHHARLKTD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PA06-1", "uniprot_id": "ATLA2_MOUSE", "id": "Q6PA06-1", "name": "Atlastin-2", "aln": "MAEGDEAARRQQPQQGLRRRRQTSDSSVGVNHVSSTTSLGEDYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNK----DSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDVYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVALKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLT-DQVSHHARLKTD---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHH9-1", "uniprot_id": "ATLA2_HUMAN", "id": "Q8NHH9-1", "name": "Atlastin-2", "aln": "MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNK----DSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLT-DQVSHHARLKTD---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VC57-1", "uniprot_id": "ATLAS_DROME", "id": "Q9VC57-1", "name": "Atlastin", "aln": "----------------------MGGSAVQVINAS----------------------------------EEHTFVLNEDALSEVLMRDEVKDRFVCVVSVAGAFRKGKSFLLDFFLRYMYSKYVHHDATDWLGGESDPLEGFSWRGGSERDTTGILMWSDIFLHDYPNGDKIAIILLDTQGAFDSQSTVRDCATVFALSTMLSSVQIYNLSQNIQEDDLQHLQLFTEYGRLALADTGKKPFQRLQFLVRDWSFPYEAEYGALGGDKILKRRLEVSDKQHPELQSLRRHISSCFTEVACFLMPHPGLNVATNPKFDGRLQDITPEFKSSLRSLVPMLLAPDNLVYKEISGQRVRARDLIQYFQSYMNIYKGNELPEPKSMLVATAEANHLTAVAAAKELYGQLMEEVCGGTRPYLSTAHLQTEHLRVKDKALFQFAAKRKMGGEEFTEKFRKQLEDDLEEVFTNYQAHNESKNIFKAARTPAVYFACAVIMYILSGIFGLVGLYTFANFCNLVMGVALLTLALWAYIRYSGELSDFGGKLDDFATLLWEKFMRPIYHGCMEKGIHHVATHATEMAVGGGAASYRSQTSVNASNGKVKRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ...:. * :.* ::*.* *:*:**..:*:::.::* : ******************:*****.* *: .*:**..:** **:****.**:**** :*.::*: * *** *:*::*:***********::*********** ****:*************************: : :**** * **:****:*** .** **.::*::**:*.::** ***.:*:** .**:::.***:*****:*****.*****:** :** .**.***:****:*** *****.:* .***::**::*::**:*:***.***** ******:*:***.*:: * : **:**** :**::.:.*: :** :*: *: ** : :****:** .:::.*** ::**.::*: **:.**** ******. ** . ***:**: *::** ::* :******:** *. ***::****: ::* :*:.* ***:.::*: .. **:.*:: .*:: : .: . .*:::: ..: ", "identical_positions": 291, "similar_positions": 168, "identity": "48.74%" }, { "cls_id": "homologset.agr.MGI:1929494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P81128-1", "uniprot_id": "RHG35_RAT", "id": "P81128-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVIVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKSHNENWLSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEVDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDETSHIDNMENER-IPFDLMDTVPAEQLYETHLEKLRNERKRAEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDRAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDPNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRG-----DTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSST-------ASIKDLAD------VDLRIVMCLMCGDPFSADDILSPVLQSQTCK-SSHCGSSNSVLLELPIGVHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AIDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLELFHPFFKDVVEKKNIIEATHMYDNVAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------EEDVEPPSYHLFREDATLPSLSKDHSKFSMELEGNDGLSFIMSNFESKLNNKVPPPVKPKPPVHFEITK-DLSYLDQGHREG--QRKSMSSSPWMPQDG---FDPSDYAEPMDAVVKPR-NEEEN----------------------------IYSVPHDSTQGKIITIRNINK--------AQSNGSGNGSDSEMDTSSLERGRK--------------VSAV-SKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGY-------------------------------KGDNAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATR-SYQTIIELFIQQCPFFFYNRPISEPPGAAPGSPSA-----------MAPTVPFLTSTPATS--QPSPPQSPPPTPQSPMQPLLS-----SQLQAEHTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YM2-1", "uniprot_id": "RHG35_MOUSE", "id": "Q91YM2-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWPSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEVDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENER-IPFDLMDTVPAEQLYETHLEKLRNERKRAEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDRAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDLNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRG-----DTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSST-------ASIKDLAD------VDLRIVMCLMCGDPFSADDVLSPVLQSQTCK-SSHCGSSNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AIDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLELFHPFFKDVVEKKNIIEATHMYDNVAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------EEDVEPPSYHLFREDATLPSLSKDHSKFSMELEGNDGLSFIMSNFESKLNNKVPPPVKPKPPVHFDITK-DLSYLDQGHREG--QRKSMSSSPWMPQDG---FDPSDYAEPMDAVVKPR-NEEEN----------------------------IYSVPHDSTQGKIITIRNINK--------AQSNGSGNGSDSEMDTSSLERGRK--------------VSAV-SKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGY-------------------------------KGDNAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATR-SYQTIIELFIQQCPFFFYNRPISEPPGAAPGSPSA-----------MAPTVPFLTSTPATS--QPSPPQSPPPTPQSPMQPLLS-----SQLQAEHTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRY4-1", "uniprot_id": "RHG35_HUMAN", "id": "Q9NRY4-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENER-IPFDLMDTVPAEQLYEAHLEKLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDPNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRG-----DTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSST-------ASIKDLAD------VDLRIVMCLMCGDPFSADDILFPVLQSQTCK-SSHCGSNNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AVDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLEIFHPFFKDVVEKKNIIEATHMYDNAAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------EEDIEP-SYSLFREDTSLPSLSKDHSKLSMELEGNDGLSFIMSNFESKLNNKVPPPVKPKPPVHFEITKGDLSYLDQGHRDG--QRKSVSSSPWLPQDG---FDPSDYAEPMDAVVKPR-NEEEN----------------------------IYSVPHDSTQGKIITIRNINK--------AQSNGSGNGSDSEMDTSSLERGRK--------------VSIV-SKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGY-------------------------------KGDNAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATR-TYQTIIELFIQQCPFFFYNRPITEPPGARPSSPSA-----------VASTVPFLTSTPVTS--QPSPPQSPPPTPQSPMQPLLP-----SQLQAEHTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF53-1", "uniprot_id": "A5PF53_DANRE", "id": "A5PF53-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMAKKQESRLPIYNLVVVGLSGTEKEKGQCGVGKSCLCNRFVRPSADDFHLDHTSVLSTSDFGGRVVNNDHFLFWGEVGRVLEDGADCRMHVVEQTEFIDDQTFQPHRSTALLPYIKRAASTKLASAEKLMYFCTDQLGLEQDFEQKQMPEGKLQVDGFLLCVDVSRGMNRNFDDQMKFVTNLYNHLSKTKKPIVLVLTKCDEGVERYIKDSHTFAITK---KNLQVVETSARSNINVDLAFLTLIQLIDKGKGKPKIIPYFEALKHQSQLIASAKDRYEWLVNHIVKNHNETWPNVSRRMQTSPEYKEYVFLEGTGKAKKLFQQHIHRLKQEHTERRRKAYLSALPLALSSLVSELDEIEHLS---WSGVQKVLESKKDFDHWFVVLDDAPWEDTPHLDNMEDDR-IPFDVLDTTAAEILFDAHLEHLRNECKRAQMRHEFKGKLASSPFVTPGKPWEEARSFIMNEDFYQWLEEPEYLDIYNRHQKAIIDRAKEDFQELLLEYSELFYELEVDAKPSKEKMGAIQEVLGEEQRFKALQKLQAERDALVLKHIHFVYHPTKETCPNCPHCVDSKIEQILASCFPAQYPSFG--KSHITDAKVDR-INLVILGKDGLARELANEIRALCTNDDHYVLEGRMYELVLRPIEGNVRLPVNSFHTSTFTPHGCLCLYNSKESLSYVVESIEKLRESTLGRRDNHMAQLPLSLLLVSKRGVGGLSDIGGETAQALISQGQQVAIKLQCNYLEPSSPGTGYGRNVNEKQINQVLKALLETRRTSTFRSCSPPAPPLPPCIRDFQQ-DQSPEADLRIVMCLMCGDSYDIDQLLAPFLLPQHCKPTSPQTSGTSVLLEQTIGGHKLTIELSLLSYHSSFATRKSRLVHGYIAVYSASRKASFETLCAFLCEVQDIIPVQMIAVGET--QIELQDSESARELLVQGEELAHELEGRFGSIVCGHGGVVGGLHKLDLLEQFFTEVLEKKTIVEASHMYESMAEAS-------STNENVY-SPHCGSPSPVTMLLDS------------------EEDMEASPPY----HDGTLTSHGGFKLPDLDSGDTFSVISDLSTFENKLNNKVPPQVRPKPSVTFDLRKPS----FNPYVDGVSHRRSLTSNVTWPLGGD--YDPSDYAEPMDAVSKPRPSYEDS----------------------------IYSVPHDSTQGKIITIRNSNR--------IHSNGGGNGSDSEGDGSSLERRRK--------------FSAARVKPRLYRDRSKRLGKFSSFRTSFSIGSDDEIGTLSRSKEDDVSP----------------------------------LKTDIT-NEEGEDPKKRNILKSL-RRPGKKARPKPRHS-ISKPLESNYFGVPLVNVVSF--------ERPIPVFIDKCIRYIEATGLTTEGIYRVSGNKAEIEGMQRQFEQDHNLDFVEKDFTVNTVAGAMKSFFSELPDPLVPYSSQEELVEAFKIN-------------DREQRLHTMKDVLRRFPRENFDVFKYVMSHLNKVGQWNRVNLMTSENLSICFWPTLMRPDFTSMDALTATR-TYQTIIETFIHQCAFFFYNQPPAESPTGLFGQPGP--MVPCGLPPSPTAAPSYCPSTPHFTPLLQSPPHSPPQSP-------------HSAPAEPQTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F8G5-1", "uniprot_id": "E7F8G5_DANRE", "id": "E7F8G5-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMAKKQDARAPTYNLVVVGLSGTEKEKGQCGVGKSCLCNRFVRPSADDFHLDHTSVLSTSDFGGRVVNNDHFLFWGEAVRMLEEGAECRMHVVEQTEFIDDQTFQPHRSTALQPYIKRAASTKLASAEKLMYFCTDQLGLEQDFEQKQMPEGKLLVDGFLLCVDVSRGMNRNFDDQMKFVTNLYNQLAKTKKPVVLVLTKCDEGVERYIKDSHTFALAK---KNLQVVESSARSNVNVDLAFITLVQLIDKSRGKPKIIPYFEALKQQSQQIATAKDRYEWLVSRIVKNHNETWPNTNRRMQTSPEYKDYVFLEGTSKAKKLFQQHVHRLKQEHIERRRKIYLSTLPQALNSLVPDLDEIDHLS---WSGVQKVLETKREFSHWFVVLDDTPWETTPHIDNMEDER-IPQDLLETPVAEGIYESHLEQLHNERKRAEMRWEFKEKLTCSPFVTPGKRWEEARSFIMNEEFYQWLEEQEYIDIYNKYQKIITDQAKEDFQELLLEYSELFYELEVDAKPSKEKMGAIQEVLGDEQRFKALQKLQAERDALVLKHIHFVYHPTKETCPSSPHCVDGKIEQHLALRYPTRYSFDGSSKSQFGEGKVDR-INLVILGKDGLARELANEIRALCTNDERYVLDGRTYELTLRPIEGNVRLPVNSFHTPTFAPHGCLCLYNSKESLSYVVDSIEKLRESTIGRRETNLVQLPLSLLLVTKRGVGSISDIGGETAQTLIQQGQQVAGRFQCSYLEPASPGVGYGRNINDKHLNQILRGLLEMRRPSVSLGSS--SPPLLPSLAGFRDSQQSTEGDLRIVMCLMCGDTYDVDQLLSPFLLPQHCRPLSNLSSGTSVLLDLSIGGQRLSIDLAILSYHSSFSLRKSRLVHGYIAVYSAKRKASMETLCAFLCEVQDIIPVQLLAVAET--QSELADSEAVRDQLAQGEELAHEIDARFSSVICGPGGVVGGLHRIDHFQPFFKEVVEKKTIVEATHMYDNVAEN--------VTNENVS-SPRCSSPS--ITLLDS------------------EDDIEPSPPYPTSRNDDTLT-RGGFKLPDLE-GDSYSLISEITNLENKINNKVPPQVRPKPNVTFDIPKTQNSSLYTDLALHGSNRRSLPS-VTWPEAG---YDPSDYAEPMDAVAKPRPTEEEN----------------------------IYSVPHDSTQGKIITIRNANK--------SHSNGAGNGSDSEADSSSLERRRK--------------LSALGVKPRLYRDRSKRLGKFSSFRTSF-IGSDDELGGTPKAKEDELGA----------------------------------QKGDTSLNEEGEDPKKRNILRSLGRRTTKKTRPKARQTSLSKPPESNYFGVPLANVVTP--------ERPIPLFIEKCIHYIETTGLSTEGIYRVSGNKAEMESMQRQFDQDPNIDLVEKDMSVNTVAGALKSFFSELPDPLVPYSMQVELVEAFKIN-------------DREHRLHTMKDVLRRFPRENYDVFKYVITHLNKVSLNSRLNLMTSENLSICFWPTLMRPDFTTMDALTATR-TYQTIIETFIHQCAFFFYNQPFADTPSGLPGQPASPTATLSSGSAYSTSYASIQPVAPPFSPAQQSPPHSPPPTPQSPIQSLLPPLHPHHTPTEQHML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX32-1", "uniprot_id": "RG190_DROME", "id": "Q9VX32-1", "name": "Rho GTPase-activating protein 190", "aln": "----------MRQFNISVIGLSGTEKDRGQVGVGKSCLCNRFMRPMADDYFIDHISVLSQSDFSGRIVNNDHFLYWGDVRKTTEEGVEYQFNIIEQTEFMDDSTFQAFKVGKMDPYSKRCTATKVFSAEKLMYICKNQLGIEKEYEQKVMPDGRLSIDGFVVVFDVSPVPNRSVEKQVEFVQNVIATILKNKKPLVLVTTKNDDAYELYVREAEKISQRKDYKSTVQLIETSAHESINIDLAFLLLAQMIDKVKNRVKIISYQESAKSRKELLDTRSEAVTRLIRNQITDYHVLWSQGSKMLSQYREWNEFLNIFGHEAGQKLFRRHMKKLRDDHLNKKLHQYLDKFALALEYLLPDIGALNISDDDAWECARNYLQNHIEFEQYFFECPQASWTELVDMDEAEDEARIPFDVLETSEAETVFRNYLNSVQQDKKKIGWKQQFKMLLEESGFVTPGKQLSEVRVLFMGRECFEALSEHDCQQIYDIHQDDIIEKSKQNFVELLLEHAQYFLQFKNVDNITQEDVRQITDVIQEDSRYKMLDRLDQERRLMLVQHLRFIHCPIRDHCPFFYNCVDSLIEEVLSDKSASNHKTPSGGGWKSSGSGSDRTLNLLIVGSEHLASDLLNDIRICTGSKGEYIYENQTYYLNYRIANG----DMEAFKAIDVYSSGLICVYSNQQSFETLKDNLERTLLCNLELEDKFEN---LPIVLVYQPQ-----DLKENEVEYLRNEGMRLSEMLHCDFIDHTQNHQKYVYDILN---IVILSLKLTEMKSYEPYPSN--------------------HTDLRILCCIFCGDQYDIENIVQPLVEESTLVKANEHS----IIVDVFIGDAKRRVEFILSSYHGTSQYR-DELIHGYIYFYSTKRRSSLANLS-ILAAQNANIPLQIIAVTESGGVNAFFNSDICQFLITEGNAVADRFKGSFMTFSADQY------VKFAFYNPFLKTAWDNKYEVENLHVEESITLDSGEGTLENSVNQMPRPPPRHESYMLSNTLGTDGSGSENYEMAPTRSLNSLNEERDISLDEIYDDNEKPKHLHQKWLEDKSDGRRNMNKNLIWNNFSGSTHAYTTGRRHIDSNLNKIRPKGPSQTLKVGEAPSRNCPAMSSSTFTLPTQQPGKLNMKNFQLVSDAVAKMNFTGSGSGSGSGSGSGSTGLGLGLGSGSGCMGDSFLEPVDKDGKRYDHAQLDGEDEDSEELAEYEQIYENEDCTESDSCASSTERRVRQQNAYYKASKKPVAAKKQKKKKVAIPVQTPRVPPFGSYVSPPEIPLHYQRMAVGGSGPEKPEPCVPEFMKSDKSPEYSMVPELAGAGIFGAENLPEYNMNQAKCLKDFEKLEKRRIKEETARQRKLQEKEKEQEKKLKRKLKQNAKGLVESAEAQFGKLMITSEQGEIPIFLNKCVEFIEKEGLDSEGIYRVPGSRAHVDMLFQRFEEDTNTEIDALDIPVNAVATALKDFFSKRLPPLFSKDIIKELEEIAGSRGVGNSKLNVEVKTDRSCRLIALKSLLQKLPPINFAILKYIFQHFVHVSDNSKLNSMDSKNLAICWWPTLIPIDFTDMGHFEQLRPYLEDIVQTMIDQFPYLFCGKDAFVMV------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *:*******::** *:*********:** **::.:** **** ***.**:*******:**:. : *: .: :::::*****:**.***..: : ** **.::**: *******:*.:***:*:::*** **:*:* :***:: .*** **..:.*::** *: : *.***:*:* ** *:. * *::::..:: * ..:*::*:**:..:*:**** * *:*** :.: ***.* *: * :.: : : .: *: . :..:: * . .: :. *::::: : * .:*** :*:::*:.:* ::: : ** :. *:. *:.::. :: . .:: *:.: :* ::*. ::.* .:*: *:: ** *:::* ** :: :*: :::: *: : ** * * *:**** .*.* ::*..: :: *.* :**. :*. * :::*::* *****::: * ::: : ::*.: * :*: ::.*:* *::*: ** ::::*::*:: * :: ** ***. **. :: ** :**:*:*.: ** :* *:** .. .*: :.: * * * :* :::*:: . . * :*:*..::*:. : :.:*: ..: .:. *.::** : * : . * .:* ::: ::* ::: :. * :: : :* * : .. ****: *::*** :. :::: *.: . . :::: ** : ::: : ***.: * ..*:**** .**:.*::*: * :*. : **:*::*: : . :.: : :.:*: :*..:.. * :. .. :: . *:. . ::* :* *: :. : ..: .*: * * . ::: : . . : . . ..:... : .. : .. : * .* * : .:: *** * . . . . : .* :*..: . : . :. : : ::*: ** ** : . * : *: *.*: :. : . : :. : *. .:*.* .. *: : : * : . . :.* *: . : **:*:::*:.:** ** :******.*.::.:: : ::*::* * :: *:.**:** *:*.***: **.. . :* * . **. :* ::*.:*:::* *. ::**:: *: :*. .::* * *:**:**:****: **: *. : * : *:: :*.* .::* .: ", "identical_positions": 358, "similar_positions": 514, "identity": "21.18%" }, { "cls_id": "homologset.agr.MGI:1929500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8I5-1", "uniprot_id": "AR6P4_RAT", "id": "Q4V8I5-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "aln": "MAHVSSRKRSRSRSRSR-GRRGSEKRSKRSSKDSSRNCSTSKSQGHKASSTSGVE--------ERSKHKAQRTSRSSSSSSSSSSSSSSSSTSSSSSS--DGRKKRGKHKDKKKRKKKKKRKKKMKRKGKE-KAVVVHQAEALPGPSLDQWHRSAGEDNDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMR-AGLLP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM93-1", "uniprot_id": "AR6P4_MOUSE", "id": "Q9JM93-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "aln": "MAHVGSRKRSRSRSRSRSGRRGSEKRSKRSSKDASRNCSASRSQGHKAGSASGVE--------ERSKHKAQRTSRSSSTSSSSSSSSSAS---SSSSS--DGRKKRAKHKEKKRKKKKKKRKKKLKKRVKE-KAVAVHQAEALPGPSLDQWHRSAGEDNDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMR-TGLLP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66PJ3-8", "uniprot_id": "AR6P4_HUMAN", "id": "Q66PJ3-8", "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "aln": "MAHVGSRKRSRSRSRSR--GRGSEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEASPSPCITERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKR--KKLKKKGKE-KAEA-QQVEALPGPSLDQWHRSAGEEEDGPVLTDEQKSRIQAMKPMTKEEWDARQSIIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDCLAFQMR-AGLLP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502P0-1", "uniprot_id": "AR6P4_DANRE", "id": "Q502P0-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "aln": "MG--GSDSDSRSRSRNR-----EENKSRSLSSSSARRPSPNHEKKHEHSS-------------EKKKMKRRRSSSSSSSSSSPSPSREKKAKKKKKRRE-AKKLKREKKKEKKEKKRQKKLALKAERAAALTASVPAPVPEEKPQTYLKTWQ-SEETKEHGPAMTDEQKAKLSTRRPLTKEEYEARQSVIRRVLDPETGRTRLIRGDGEILEEIVSKERHKDINKQSTRGDGDAFQKR-LGISR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCD4-1", "uniprot_id": "Q9VCD4_DROME", "id": "Q9VCD4-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "aln": "MG--KSEKKSK------------------------------------------------------KKHKEKR------------------------------REHKEKHKSKKSKKHNRK------------KEESPPIASPTP---IQPERVNQEEEDDFAIPIALMNS--KSHAPETPEEYQRRQSQIRKEVDPVTGRVRLIKGDSEVLEEIVTKERHLEINKKATRGDGEFYEARSLDAAKRRK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * . *: .* * :* : :: * *.*: :*:::: . * :. : . .:. . :: .: * * **:: *** **: :** ***.***:**.*:*****:**** :***::**** :: * . ", "identical_positions": 48, "similar_positions": 43, "identity": "19.43%" }, { "cls_id": "homologset.agr.MGI:1929501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES40-1", "uniprot_id": "PRAF3_RAT", "id": "Q9ES40-1", "name": "PRA1 family protein 3", "aln": "----------------MDVNLAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGFLSPFNMILGGIIVVLVFTGFVWAAHN----KDILR-RMKKQYPTA---------FVMV-VMLASYFLISMFGGVMVFVFGITFPLLLMFIHASLRLRNLKNKLENKMEGIGLKKTPMGIILDALEQQEDSINKFADYISKARE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R5J9-1", "uniprot_id": "PRAF3_MOUSE", "id": "Q8R5J9-1", "name": "PRA1 family protein 3", "aln": "----------------MDVNLAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGFLSPFNMILGGVIVVLVFMGFVWAAHN----KDILR-RMKKQYPTA---------FVMV-VMLASYFLISMFGGVMVFVFGITLPLLLMFIHASLRLRNLKNKLENKMEGIGLKKTPMGIILDALEQQEDNINKFADYISKARE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75915-1", "uniprot_id": "PRAF3_HUMAN", "id": "O75915-1", "name": "PRA1 family protein 3", "aln": "----------------MDVNIAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISIVGFLSPFNMILGGIVVVLVFTGFVWAAHN----KDVLR-RMKKRYPTT---------FVMV-VMLASYFLISMFGGVMVFVFGITFPLLLMFIHASLRLRNLKNKLENKMEGIGLKRTPMGIVLDALEQQEEGINRLTDYISKVKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ59-1", "uniprot_id": "Q9VJ59_DROME", "id": "Q9VJ59-1", "name": "PRA1 family protein", "aln": "MTTPSTSVGDAAAALSGNLQLPPLRTLDDFILGSARFQLPNLKDFEKWGNRVVKNLLYYQTNYFLLFITIYVLMIFFNPSKIITG-LLVQALIIGVIWQFFSGKSKKNFIASRLTGGNANAAEQNAQQKWYILAGALLGGYLLLHLLSAVLLTIFTVLLPISLTFIHASLRLRNIKNKLTNSIESFAPS-TPMGSLLDALNVRAEGVFN----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::.***: ***: ** ** *:::*:.**.****.*********::: : :: *:.* ::* * ::* :: *.:* .. *:.: *:. ..: :::. .:*..*:*: ::..*:: :* : :*: * **********:**** *.:*.:. . **** :****: : :.: . ", "identical_positions": 67, "similar_positions": 74, "identity": "30.59%" }, { "cls_id": "homologset.agr.MGI:1929507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH07-1", "uniprot_id": "AR6P6_MOUSE", "id": "Q8BH07-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 6", "aln": "MSFVES-WRFAGARRRRQVTPGPATRPGYSDYTQGDSWGEGEGDEDEGCDQVARDLRAEFSARASSETKRAPLLPRVGDGSPVLPDKRNGIFPATAAKRTQARRWPIQALSILCSLLFAVLLAFLLAIAYMIVKELHAENLKNEDDIHTGLLGFWSLLIISLTAGLSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGIVAALTVAWCLM-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FV2-1", "uniprot_id": "AR6P6_RAT", "id": "Q68FV2-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 6", "aln": "MSFVES-WRSVGPRRRRQVTPGPVTRSVYSDYTQGNSWSE---DGDEGCDQVARDLRAEFSARASSESKRAPLLPRIGDGSPVLPDKRNGIFPATAAKRTQARRWPIQALSILCSLLFAVLLAFLLAIAYLIVKELHTENSKNEDVVDTGLLGFWSLLIISLTAGLSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGVVAALTVAWCLM-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N6S5-1", "uniprot_id": "AR6P6_HUMAN", "id": "Q8N6S5-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 6", "aln": "MSFAESGWRSA-LRRRGPGTPGPVARPSYSSFTQGDSWGEGEVDEEEGCDQVARDLRAEFSAGAWSEPRKRSVLPPDGNGSPVLPDKRNGIFPAAAGSRAQPRRWPVQVLSILCSLLFAILLAFLLAIAYLIVKELHAENLKNEDDVDTGLLGFWTLLIISLTAGFSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGIVAALTVAWCLM-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5G2-1", "uniprot_id": "A0ACD6B5G2_DANRE", "id": "A0ACD6B5G2-1", "name": "", "aln": "------------MQRSARDKDGP-SLDIYSD------------DEETIVLAERRTAMEDTNAGSNVRSENRGATP----GRP----------PVRQRYWRNTHLWPARIGSVLCSIIFVSFIAVLIAFLYIILKDLKTEKITTEDGSEVRLLGFWSILVLSSMAGVLCCSFSWTLTYFDSFEPGMFPPTPLSSSRYKKMTGHSFHMGYSMAILNGIVAALTLICLQSRVQQRAELLLKCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . ** : **. * : * : .* : .... * * * *. :.: ** : *:***::*. ::*.*:*: *:*:*:*::*: ..** .. *****::*::* **. *******:*****************.:*:**:****************:*****: ", "identical_positions": 86, "similar_positions": 48, "identity": "35.83%" }, { "cls_id": "homologset.agr.MGI:1929509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LM55-1", "uniprot_id": "A0ABK0LM55_RAT", "id": "A0ABK0LM55-1", "name": "", "aln": "MGWGLSPRTMN---NTNC-SILPWPAAVNHVFTIYLVLLLVLGLLLNGLALWVFCYRMH-QWTETRVYMTNLAVADVCLLCSLPFVLYSLKY--------STSDTPICQLSQGIYLVNRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAGAVCVALWVIVVTSLVLRWRLGIQEGG---FCFSSQNRYNFST---TAFSLLGFYLPLAIVVFCSLQVVTALARRPATDVGQVEATQKATRMVWANLAVFIICFLPLHLILTVQVSLNLH--TCAARNIFSRALTITAKLSDINCCLDAICYYYMAKEFQDASLPATA-SSTPHKSQDTQSLSLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES90-1", "uniprot_id": "GPR35_MOUSE", "id": "Q9ES90-1", "name": "G protein-coupled receptor 35", "aln": "---------MN---STTCNSTLTWPASVNNFFIIYSALLLVLGLLLNSVALWVFCYRMH-QWTETRIYMTNLAVADLCLLCSLPFVLYSLKY--------SSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAAAVCVALWVIVVTSLVVRWRLGMQEGG---FCFSSQTRRNFST---TAFSLLGFYLPLAIVVFCSLQVVTVLSRRPAADVGQAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSLNLN--TCAARDTFSRALSITGKLSDTNCCLDAICYYYMAREFQEASKPATS-SNTPHKSQDSQILSLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC97-1", "uniprot_id": "GPR35_HUMAN", "id": "Q9HC97-1", "name": "G protein-coupled receptor 35", "aln": "---------MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQ-QWTETRIYMTNLAVADLCLLCTLPFVLHSLR---------DTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGG---FCFRS-TRHNFNS---MAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN--ACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RLI3-1", "uniprot_id": "A0A8M1RLI3_DANRE", "id": "A0A8M1RLI3-1", "name": "", "aln": "----------------MSNCSLSITAGIQNFQLAVQIPTFIFGVPANIYVLIMFCRRARSAWTDMNIYISNMAVADCVMLVLLPIRIMSIYENTLVSRFWDQTNKELCYVLVSVHYVNMYVSIFTITAISIVRFIAIKYPLKAREIFSRRKALVVCALIWLVTCSLSVAFHRVDDPKHNSTIKCFQKNKKEELPLTFILVLNVVGFISPFLIMTFCSIRVIFTLRKQ--LDIGSRAEKMQCIFIMVANLCVFVLCFFPVHFGFLLKYITQAHKYSCDAQIWSHNFVHAAICVSSMNCALDCVTYYFATRTSWTIRCCRQK-THEGYKCHYSSTRSSQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. ...:: :::*: * .* :** * : **: .:*::*:**** :* **: : *: . ::. :* : .:: .* *:** :***:: *::*:::**:** : * *:* .**. :*::. * :. : . ** . .: :: .: ::** *: ::.***::*: .* :: *:*. . :. :: *** **::**:*:*. : :: : :* . : : :*. **.**.: **: :: : :*.: : : ", "identical_positions": 70, "similar_positions": 109, "identity": "20.77%" }, { "cls_id": "homologset.agr.MGI:1929510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DGF4-1", "uniprot_id": "ZFAN6_RAT", "id": "Q6DGF4-1", "name": "AN1-type zinc finger protein 6", "aln": "MAQETNHSQAPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAASVSSLSESLPVQCADGSVPDAQSALDSTSSSMQPGPVSNQSLLSESVAPSQVDSTSVDKAVSETEDLQGPRAEGLVPLECDPPSSVSDTTQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTG-FECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCH6-1", "uniprot_id": "ZFAN6_MOUSE", "id": "Q9DCH6-1", "name": "AN1-type zinc finger protein 6", "aln": "MAQETNHSQAPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAASVSSLSESLPVQCADGSVPDAQSALDSTSSSMQPGPVSNQSLLSESVAPSQVDSTSVDKAVSETEDLQGPRAEGLVPLECDPPSSVSDTTQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTG-FECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6FIF0-1", "uniprot_id": "ZFAN6_HUMAN", "id": "Q6FIF0-1", "name": "AN1-type zinc finger protein 6", "aln": "MAQETNHSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPATSVSSLSESLPVQCTDGSVPEAQSALDSTSSSMQPSPVSNQSLLSESVASSQLDSTSVDKAVPETEDVQ---------------ASVSDTAQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTG-FECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHF4-1", "uniprot_id": "Q9VHF4_DROME", "id": "Q9VHF4-1", "name": "", "aln": "MERESNPMQP--MCRSGCGFYGNPATDGLCSVCYKDSLRKKQQ-----PPVSSTPVSVPSPQPSPTFSPAIAITNTAQPTVTSLQQPHNDVKEKITEEAAAAAKVNSEAITSATGPNTSTQ---------------AAASANEEDDKDKEDD--KDAKKKKNRCGECRKKVGLTG-FQCRCGGLYCAVHRYSDKHNCTFDYREHGAQEIRRNNPVVVGEKIQKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W371-1", "uniprot_id": "Q9W371_DROME", "id": "Q9W371-1", "name": "AN1-type domain-containing protein", "aln": "---MRSASVPNIIIWSGMDAGTQSAMS-IQLHGFSHHLEQRDQ------------------------------EERDQGDAQEQQQPQQQQDQPPMEE------QDSRAVNSKD----------------------GAANQDTSADSGQDQDGNQAQDSTKKRCDKCGKKLGITGGFPCRCGGTYCAVHRYSDRHECNFDYRQMGAIQIRRDNPVVVASKLRKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* . :. . : :.. *.:::. : . . ** .: .* :* :: . .:.. . . ::.. : ...*:** * **:*:** * ****. **.****** *:*.::*: .* :**::*****..*::*:", "identical_positions": 41, "similar_positions": 59, "identity": "18.3%" }, { "cls_id": "homologset.agr.MGI:1929511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15239-1", "uniprot_id": "NDUA1_HUMAN", "id": "O15239-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1", "aln": "-MWFEILPGLSVMGVCLLIPGLATAYIHRFTNGGKEKRVAHFGYHWSLMERDRRISGVDRYYVSKGLENID-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35683-1", "uniprot_id": "NDUA1_MOUSE", "id": "O35683-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1", "aln": "-MWFEILPGLAIMGVCLVIPGVSTAYIHKFTNGGKEKRVARVQYQWYLMERDRRISGVNRYYVSKGLENID-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QQ42-1", "uniprot_id": "F1QQ42_DANRE", "id": "F1QQ42-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1", "aln": "MWWHEILPGLAIMTVCLYIPGIATAQIQKFTNGGKEKRVVRAAYQWYLMERDKKVSGCNKHYVSKGLENIK-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYC4-1", "uniprot_id": "A8DYC4_DROME", "id": "A8DYC4-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1", "aln": "-MWFEILPGAVIITTLLSVPIYAMYGLDKLMIGNAFRRNMDERFSRVMYQRDFRLT--DNPYKMNGLEQIPDEEVKKEEKDPNEDSDDPAIVKKREKERKLREKQLKKEEKLREKQLKEEEKQKKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.***** :: . * :* : :.:: *. :* : : :** ::: :. * :***:* ", "identical_positions": 17, "similar_positions": 22, "identity": "13.49%" }, { "cls_id": "homologset.agr.MGI:1929512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2PE16-1", "uniprot_id": "Q2PE16_DROME", "id": "Q2PE16-1", "name": "LITAF domain-containing protein", "aln": "MDQKRAMLYPQVDFNAPTAPSPTPTRELGNPIANGLP---------------IEAPPSYDVAVSVPVAPAVSAPAIAPARPPPVVVVEQPAPQPPTVVPTDTLHLGPNRSRVLCPACGANKTTRMTHTANSRTHMVAGLLCLVGFCCCACFVPYCMNSCRTGNHYCRKCNTFLGAYNPKGMNR--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MME9-1", "uniprot_id": "Q8MME9_DROME", "id": "Q8MME9-1", "name": "LITAF domain-containing protein", "aln": "------MQYNQQPAGAPGYPHQMP-------------------------------PPSYEQVVHVQAPVRVVHHTTAP---PPVVIIQHQAVLP----------VGPDPTFITCPHCHVQKLTRVEYSPSVKTHCMAAILCIVGLWCCAC-LPYCATSCMNANHFCGNCNKFVGVYNSD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W217-1", "uniprot_id": "Q9W217_DROME", "id": "Q9W217-1", "name": "LITAF domain-containing protein", "aln": "----MDSVYPAAPLEAPKGSVELQAT----PEQQHLL---------------PPAPPSYDQATTTPAETTGPAPVPASTSTTQHTVVVVPGSPY-----------GPEPMDVQCPYCHNYARTRVSFKPNSRTHLIALILCLFQLYCCVC-LPYCISSCMNTNHYCGMCDRYLGTYDRK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W221-1", "uniprot_id": "Q9W221_DROME", "id": "Q9W221-1", "name": "LITAF domain-containing protein", "aln": "MDSKQPPPYSEQSGYTPAQTYQPGGP---------------------------TQPPLYPPMPQPPQSSTVIIQTTTTSNLVPIGS---------------------GPTRIRCPSCHAEVLTTVKSTPSGRTHCWALILCLFICWPCVC-LPYCMDSCQNANHYCPNCSAYIGTYEN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K8A8-1", "uniprot_id": "A0A0B4K8A8_DROME", "id": "A0A0B4K8A8-1", "name": "LITAF domain-containing protein", "aln": "MEKN--FQYENMQPQAPGFQAPPSYD---------------------------SAP--QQVYPQLHQGQGVILQGENTENYESIGNNAPPNVLG------------QCPSVATCPSCGVRRETKVEFEPSTKTHLLALLICMLGGICCCC-IPYCTDSCQSAKHTCTSCGAYVGTYKN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0T0-1", "uniprot_id": "LITAF_RAT", "id": "P0C0T0-1", "name": "Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog", "aln": "MSAPGPYQAAAGPSVMP--TAPPTYEETVGVNSYYPT---PPAPQPGPATGLITGPDGKGMNPPSYYTQPVPVPNANAIAVQTVYVQQPISFYD-------------RPIQMCCPSCNKMIVTQLSYNAGALTWLSCGSLCLLGCVAGCCFIPFCVDALQDVDHYCPNCKALLGTYKRL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLJ0-1", "uniprot_id": "LITAF_MOUSE", "id": "Q9JLJ0-1", "name": "Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog", "aln": "MSAPGPYQAAAGPSVVP--TAPPTYEETVGVNSYYPT---PPAPMPGPATGLITGPDGKGMNPPSYYTQPVPVPNANAIAVQTVYVQQPVSFYD-------------RPVQMCCPSCSKMIVTQLSYNAGALTWLSCGSLCLLGCVAGCCFIPFCVDALQDVDHYCPNCKALLGTYKRL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99732-1", "uniprot_id": "LITAF_HUMAN", "id": "Q99732-1", "name": "Lipopolysaccharide-induced tumor necrosis factor-alpha factor", "aln": "MSVPGPYQAATGPSSAP--SAPPSYEETVAVNSYYPT---PPAPMPGPTTGLVTGPDGKGMNPPSYYTQPAPIPNNNPITVQTVYVQHPITFLD-------------RPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIAGCCFIPFCVDALQDVDHYCPNCRALLGTYKRL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GMG8-1", "uniprot_id": "LITAF_DANRE", "id": "Q6GMG8-1", "name": "Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog", "aln": "MAMPMPTAPPMENTTLVGHPPPPSYDEISGANPYYPAGPYPPADMKASGPPPYPTQEYNQMYPPTAQGQPVTSP---VVAVQTVYVQPGLVFGN-------------VPVQAHCPVCSQSVITRLEYSSGPLVWLSCAGLAVFGCIYGCCLIPFCIEDLKDVTHHCPNCSSVLGVHKRF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1P0-1", "uniprot_id": "Q9W1P0_DROME", "id": "Q9W1P0-1", "name": "LITAF domain-containing protein", "aln": "--MS-------SFARVP-STPPPSYEEAMG------------------------------------------------WETRRSHSTTWLLAEN-------------TSSLMICPMCHDEIETTTKIRRRWIAYVASGIVLFTTCGIGCWLIPCILDCFNEIHHSCPVCKATLGIVPQQDQRWPT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IRE5-1", "uniprot_id": "Q8IRE5_DROME", "id": "Q8IRE5-1", "name": "LITAF domain-containing protein", "aln": "--MSKPGSAPPQFTYVPPPSAPPSYQEAVGG---------------------------------VKPVGPYTPVVAPATTANTTIVTTVVPISR-------------TSTHMICPSCHAEIETTTRTEPGMIAYLSGFLIALFGCWLGCCLIPCCIDDCMDVHHSCPNCRAYLGRYRR-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * : . : . :* * * * :* ", "identical_positions": 8, "similar_positions": 6, "identity": "4.32%" }, { "cls_id": "homologset.agr.MGI:1929514", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2K5-1", "uniprot_id": "LST8_RAT", "id": "Q9Z2K5-1", "name": "Target of rapamycin complex subunit LST8", "aln": "MNTTPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNALEITPDRSMIAATGYQHIRMYDLNSNNPNPIISYDGVSKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGTSHIWDLK-TDHNEQLIPEPEFSITSAHIDPDASYMAAVNSAGNCFVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSSNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCJ1-1", "uniprot_id": "LST8_MOUSE", "id": "Q9DCJ1-1", "name": "Target of rapamycin complex subunit LST8", "aln": "MNTTPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNALEITPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVSKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLK-TDHNEQLIPEPESSITSAHIDPDASYMAAVNSAGNCYVWNLTGGIGDDVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSSNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVC4-1", "uniprot_id": "LST8_HUMAN", "id": "Q9BVC4-1", "name": "Target of rapamycin complex subunit LST8", "aln": "MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLK-TDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803V5-1", "uniprot_id": "LST8_DANRE", "id": "Q803V5-1", "name": "Target of rapamycin complex subunit lst8", "aln": "MNVNQGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNSLEVTPDRSMIAAAGYQHIRMYDLNSNNPNPVINYDGVSKNITSVGFHEDGRWMYTGGEDCMARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGVIHIWDLK-TDHNEQLIPEPDVSVNSVHIDPDASYMAAVNSSGNCYVWNLAGGMGDEVTQLIPKTKIPAHKRYSLRCKFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSNNPGETSRGWMWDCAFSGDSQYIVTASSDNLARLWCVETGEIKREYSGHQKAVVCLAFNDSVLG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W328-1", "uniprot_id": "LST8_DROME", "id": "Q9W328-1", "name": "Protein LST8 homolog", "aln": "MGDQQ------QLILATGGYDHTIKVWQAHTGNCIKTMRFVETSQVNALDRTPDKTRLAACGYQCIRLYDLESNCTAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIWDMIAAPPHCSRIFDCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVK-SERHERIVPEVDASIQDVAISPDGRYLAAANNKGNCYIWSLTS-QDQKMSTLRPNRKIPAHSRYILRCKFSPDSRLLLTTSGDGTVCIWKTDD-FSKWRELCIEN--------YWVWDAAFSADSKWLFTASSDGIARLWKLQTKSSIRDYTGHTKAITALSFKDEIVGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41318-1", "uniprot_id": "LST8_YEAST", "id": "P41318-1", "name": "Target of rapamycin complex subunit LST8", "aln": "----------MSVILVSAGYDHTIRFWEALTGVCSRTIQHSD-SQVNRLEITNDKKLLATAGHQNVRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRS--PSIPRNYKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWEMPN--HTDASHLKPVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDDDFKLETTLDGHQR--------WVWDCAFSADSAYLVTASSDHYVRLWDLSTREIVRQYGGHHKGAVCVALNDV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**.:.*****::.*:* :* * :*::. : **** *: * *:. :*: *:* :*:**:.:. . *: .::* *:: :.*::*..** *..** ::**: : * :. :**:* . :**** *: .:.* :**: .: .:: ** : *: . : .*. :**.*. ***::*.:.. . : * * *: **. * : :*.* * * *.* * :* .: *. * .. *:*..***.** ::.***** .*** :.* . *:* ** *. ..::::* ", "identical_positions": 98, "similar_positions": 110, "identity": "29.7%" }, { "cls_id": "homologset.agr.MGI:1929518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZJD4-1", "uniprot_id": "A0A8I5ZJD4_RAT", "id": "A0A8I5ZJD4-1", "name": "Zinc finger protein ZIC 5", "aln": "MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLAGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQTSGHGPSPPTQALPELPQATAPAARSPASGTHPGARTHHDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPPALSGYTATNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDG-GGSALFPALHDSPGAPGG--HPLNGQMRLGLAAAAAAAA-ELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAP----HPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAG-----------PPAPADSGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGA----------------------------------------------------------------LGYSSVGTPVGDTLSP------------------------------VLDPTRSRSS-TLSPQVTNLNEWYVCQAGGAPSHLHTPSSNGTTSES-------------------------------EDEEMYGNPEVMRTIH--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQ40-1", "uniprot_id": "ZIC5_MOUSE", "id": "Q7TQ40-1", "name": "Zinc finger protein ZIC 5", "aln": "MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLVGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQASGQGPCPPSQGLPGLFQVPAPAARSVASGTHPGARTHPDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPP-ALSGYTATNSGGGSSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDG-GGSALFPALHDSPGAPGG--HPLNGQMRLGLAAAAAAAA-ELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAP----HPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAG-----------PPASADSGVKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGA----------------------------------------------------------------LGYSSVGTPVGDPLSP------------------------------VLDPTRSRSS-TLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSES-------------------------------EDEEMYGNPEVMRTIH--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T25-1", "uniprot_id": "ZIC5_HUMAN", "id": "Q96T25-1", "name": "Zinc finger protein ZIC 5", "aln": "-MEPPLSKRNPPALRLADLATAQVQPLQNMTGFPALAGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPP-ALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAG-PGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGP----------------------------------------------------------------LGYSSVGTPVGAPLSP------------------------------VLDPARSHSS-TLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSET-------------------------------EDEEIYGNPEVVRTIH--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39768-1", "uniprot_id": "OPA_DROME", "id": "P39768-1", "name": "Pair-rule protein odd-paired", "aln": "-------------------------------MMMNAFIEPAQHHLASYGLRMSPNTTASNSNAQQQQQQQLEMTQQQQQQQQQQQQQQQQDQESAAATAAAYQN-------------------------------------------------SGYGHFNS--------YASRDFLLGRREAEYGVAGSAGQASAAADSMLFSGFPAQAAELGSGFGQHPFHS-----------------------------HHHHHQMRMGMADAYAAGH------------PYNHHGNFPTAAVHHPVVHHPS---------HHAMSAMHPAGAGAFLRYMRHQPASS---------------------------ASSVKQEMQCLWIDPD--------------QPGLVPPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAGSSSGVSSLSGGSGIKSSPHSIKSEPNPMHSVHLGASSSGSSSTASSSASHLLQHQQHQHQQQQQQQQHQQQAQQQQQLTAHPSDPKSSPALQLMAASASAYLPPPLGPPPSHHHHPHHHQAAPSPGAAAASASMLHHNHHLLYHPAAQHHPPSDWYHTTAPSGSAEAMNPLNHFGHHHHHHHLMHPGAATAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: : : :: . .::... .*:* . * : .*.:* : *** ** ****:* * : . *.: *. ..:. :. * :.: * . * * : ***:*:* * **. * . ..:: :.*. ... * * :* .. .*..*:: **.. ..:*:*: * *:**: * . .* *.*.*.* :***:*.*:********* ::*.*** .*.*:*:********:************.**.*****************************.:****:******************** *:*.*****************:* : **. ** ** *:. . *. . .*: .:** :*. .:. . : . .*** * * : ::... . *..*.:..:: ", "identical_positions": 188, "similar_positions": 129, "identity": "23.86%" }, { "cls_id": "homologset.agr.MGI:1929519", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "----------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETRE--GPSSGYNPNFNAADAILKKNSDQ-VDLDVN-KLTNVTSRVLN-------------------------------TPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKH-QLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLY-------KEVGFQWAIRILSFICLTCLICASVLARER--------------------------------------------------TKPVVQP------FKSKAEVAKW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFAD-KFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVAN-YNHFIIFNSALMAAGAACYIISRHICVGAKLCKF--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08777-1", "uniprot_id": "MCH5_YEAST", "id": "Q08777-1", "name": "Riboflavin transporter MCH5", "aln": "----------------------------------------------------------------------------MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHD-------------------------------SDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDN-QLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKER--------------------------------------------------LPHVIE--------NSKDGESRWR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSD-KFG-RFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTAD-YQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP------------------------------------------------------TPPDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYNEFLDY-FNE--GKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLI-------GNYGWRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVN--RLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMY--DLTDS-YAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS---------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDED-------------------------------DDDEESVYGELPPPPDGGYG-WVICFASFMCNMIVDGIAYTFGIFLEEFVAY-FHE--GKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLL-------EEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVN--SLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIY--DMTHT-YDLPFYMAGALFGISTITSFLAPCLKRCSPSE-ETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O35308-1", "uniprot_id": "MOT3_MOUSE", "id": "O35308-1", "name": "Monocarboxylate transporter 3", "aln": "--------------------------------------------------------------------------------------------------------------------MG-AGGPRRGA-----------------------------------------------------------------------------GPPDGGWG-WVVLGACFVVTGFAYGFPKAVSVFFRELKRD-FGA--GYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLG-------ERFGWRGGFLLFGGLLLHCCACGAVMRPP-------------------------------------------------PGPPPRRD-------PSPHGGPAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRRLLDVAVCTDRAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLV--DALKN-YEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGASDPEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70461-1", "uniprot_id": "MOT3_RAT", "id": "O70461-1", "name": "Monocarboxylate transporter 3", "aln": "--------------------------------------------------------------------------------------------------------------------MG-AGGPRRGA-----------------------------------------------------------------------------GPPDGGWG-WVVLGACFVITGFAYGFPKAVSVFFRELKRD-FGA--GYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLG-------ERFGWRGGFLLFGGLLLHCCACGAVMRPP-------------------------------------------------PGPQPRPD-------PAPPGGRAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRQLLDLAVCTDRTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLV--DALKN-YEIIFYLAGSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPE--PEEEAVPDLSHESVGGHEAHGQNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95907-1", "uniprot_id": "MOT3_HUMAN", "id": "O95907-1", "name": "Monocarboxylate transporter 3", "aln": "--------------------------------------------------------------------------------------------------------------------MG-AGGPRRGE-----------------------------------------------------------------------------GPPDGGWG-WVVLGACFVVTGFAYGFPKAVSVFFRALMRD-FDA--GYSDTAWVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLL-------ERFGWRGGFLLLGGLLLHCCACGAVMRPP-------------------------------------------------PGPGPRPR-------RDSAGDRAGDAPGEAEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLV--DVLKN-YEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTE--PEIEARPRLAAESV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5K3-1", "uniprot_id": "A0ACD6B5K3_DANRE", "id": "A0ACD6B5K3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MGGIVEDRETA-----------------------------------------------------------------------------GAPDGGWG-WVVLLGGFVITGFSYAFPKAISVYFKELMHD-FGC--GYKDTAWISSIILAMLYGSGPISSIMVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLGLALNFQPSLIMLGAYFDKRRPLANGLAAAGSPVFLSALSPLGQLLL-------DQYGWRGGFLITGGLLLNCCTCGAVMRPL-------------------------------------------------KLKERKACNQELKEMLPPEAGQEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVCENNNDKKPSKKKLLDFSVLRDKGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGVPDKEAAFLLSIIGFIDIFARPTCGVVAGLKWVRPKMSYFFSLALLFNGLTDVCSATSTDYKGLIIFCVFFGLSYGMVGALQFEVLMGIVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLV--DKYKN-YELIFYMAGGELITAGIFLALASFCCISQKKRKDS--------PQTQQTYVEVNPER---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "----------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDDINGNTSIS-----------------------------------------------------------------------IEVPDGGYG-WFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQ-------KRGVKWALIAQCIICTSLSTIALMLTRTT----------------------------------------------------------------HQGLRQHKR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIAD--KYGSLTVGMILHLVMAILCWAMWIP-CKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYG-WVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLS------DFGNTRWCLRIIGISCSISVLVAIALLKER--------------------------------------------------------------NPTPAIGLKSPR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGD--KFGRANVTIVLTTLLTIYMFAFWIP-AHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:** *.: :: . . . . : .: : . * . . : : .. * . .: * :* :* * .:. * : . : . : :. . . . : . . : . .* * .. . . * . : . . : : * : . ", "identical_positions": 15, "similar_positions": 56, "identity": "1.52%" }, { "cls_id": "homologset.agr.MGI:1929520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70251-1", "uniprot_id": "EF1B_MOUSE", "id": "O70251-1", "name": "Elongation factor 1-beta", "aln": "MGFGDLKTPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSGPPPADLCHALRWYNHIKSYEK-EKASLPGVKKSLGKYGPSSVEDTTGSGAADAKDDDDIDLFGSDDEEESEEAKKLREERLAQYESKKAKKPAV-VAKSSILLDVKPWDDETDMTKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6IPG1-1", "uniprot_id": "EF1B_RAT", "id": "A6IPG1-1", "name": "Elongation factor 1-beta", "aln": "MGFGDLKTPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAISGPPPADLCHALRWYNHIKSYEK-EKASLPGVKKSLGKYGPVSVADTTGSGAADAKDDDDIDLFGSDDEEESEDAKRLREERLAQYESKKAKKPAV-VAKSSILLDVKPWDDETDMTKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24534-1", "uniprot_id": "EF1B_HUMAN", "id": "P24534-1", "name": "Elongation factor 1-beta", "aln": "MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEK-EKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPAL-VAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96827-1", "uniprot_id": "EF1B_DROME", "id": "O96827-1", "name": "Probable elongation factor 1-beta", "aln": "MAFGDVTTPQGLKELNAFLADNSYISGYTPSKADLSVFDALGKAPSADNVNVARWYRHIASFEAAERAAWSGTPLPQLAGGKPTVAAAAKP-AAD--DDDDVDLFGSDDEED-EEAERIKQERVAAYAAKKSKKPAL-IAKSSVLLDVKPWDDETDMKEMENNVRTIEMDGLLWGASKLVPVGYGINKLQIMCVIEDDKVSIDLLQEKIEEFEDFVQSVDIAAFNKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32471-1", "uniprot_id": "EF1B_YEAST", "id": "P32471-1", "name": "Elongation factor 1-beta", "aln": "MASTDFSKIETLKQLNASLADKSYIEGTAVSQADVTVFKAFQSAYP----EFSRWFNHIASKAD-EFDSFP----------------AASAAAAEEEEDDDVDLFGSDDEEADAEAEKLKAERIAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIPIGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQSTDIAAMQKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *... *: ** ***:***.* . *:**::**.*. . . . **:.** * * : . :: . *:: :***:********* :*:::: **:* * :**: *** *** : **********:: :: *::*: :** **: :::*:*:**:**** **:*****. * *::.* **.*** *:**::*:", "identical_positions": 93, "similar_positions": 61, "identity": "40.97%" }, { "cls_id": "homologset.agr.MGI:1929538", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K264-1", "uniprot_id": "A0A0G2K264_RAT", "id": "A0A0G2K264-1", "name": "Small ribosomal subunit protein mS29", "aln": "MRTKTMLTGMTRFFSRVQKLDPRCFLHVSVQAPQ------NNQVPAE-RPRAVSRTSDSDPAK------HGEQHEGQHYSIPP---------QDLKTVFPHG-LPPRYAMQVKTFGEACL--MVRKPALELLGYLKN----TNFAHPAVRYLLYGEKGTGKTLSLCHAVHFCAKSDWLILHIPDAHLWVKNCGELLQSTYNKQRFDQPLEASTWLKNFKTTNERFLG--QIKVQEKYVWNKRESTEKGSP-------LGEVVEQGLTRVRNATDAVGVVLKELKTQSSLGLFHLLVAVDGVNALWG-RTTLKR-EDRTLIAPEELALVRNLRKMVK--NDWHGG--AIVLSLSQTGSLFKSR---------TAYLPHELLGKEGFNALEP--FLPILISNYNPKEFESSFQYYLENNWLQHEKGSISLCTHAYLRYPSLLSSAHPATQGLRSSFLSRPDLMACIANI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER88-1", "uniprot_id": "RT29_MOUSE", "id": "Q9ER88-1", "name": "Small ribosomal subunit protein mS29", "aln": "-----MLTGITRLFSRVQKLDPRCFLHMSVQATQ------NSQVPAE-RPRTVSRTSDSDPAK------HGEQHEGQHYSIPL---------QDLKTVFPHG-LPPRYMMQVKTFGEACL--MVRKPALELLGYLKN----TNFAHPAVRYLLYGEKGTGKTLSLCHAVHFCARHDWLILHIPDAHLWVKNCRELLQSTHNKQRFDQPLEASTWLKNFKTTNERFLS--QIKVQEKYVWNKRESTEKGSP-------LGEVVEQGLTRVRNATDAVGVVLKELKAQSALGLFHLLVAVDGVNALWG-RTTLKK-EDRTLIAPEELSLVHNLRKMVK--NDWHGG--AIVLSLSQTGSLFKSR---------TAYLPHELLGKEGFNALEP--FLPILIPNYNPKEFESSFQYYLENNWLQHEKASTEEGRKE-LRF---LSNCNPEQ-------LER--LCASL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51398-1", "uniprot_id": "RT29_HUMAN", "id": "P51398-1", "name": "Small ribosomal subunit protein mS29", "aln": "----MMLKGITRLISRIHKLDPGRFLHMGTQARQSIAAHLDNQVPVE-SPRAISRTNENDPAK------HGDQHEGQHYNISP---------QDLETVFPHG-LPPRFVMQVKTFSEACL--MVRKPALELLHYLKN----TSFAYPAIRYLLYGEKGTGKTLSLCHVIHFCAKQDWLILHIPDAHLWVKNCRDLLQSSYNKQRFDQPLEASTWLKNFKTTNERFLN--QIKVQEKYVWNKRESTEKGSP-------LGEVVEQGITRVRNATDAVGIVLKELKRQSSLGMFHLLVAVDGINALWG-RTTLKR-EDKSPIAPEELALVHNLRKMMK--NDWHGG--AIVSALSQTGSLFKPR---------KAYLPQELLGKEGFDALDP--FIPILVSNYNPKEFESCIQYYLENNWLQHEKAPTEEGKKE-LLF---LSNANPSL-------LER--HCAYL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W253-1", "uniprot_id": "Q9W253_DROME", "id": "Q9W253-1", "name": "Small ribosomal subunit protein mS29", "aln": "---MKMIRNRFGSLSRVSAQLQRHVQQMSTNAAAS---------PAEGATISEFRTAVSNPGE------HSAMQVAKFYTIPA---------EQKKQIFTGGGLPKQYEQQIKTFTEACL--MVRNPALELLQYIKD----GDLTKPVVRYVLYGENGTGKTLTMAHVLHYGALNDFLLVHVPWAPNWMKRPKEASNAAGQEGMIDLPFDAAAWLVHFKTQNGPLLQRLQLKTSKEYVWSKRESTPAGSS-------LIELVEHGIARIKYASETTAALIAELKQLSTAGQCKVMVAIDGFNAFFHPVTRIFS-DNKQLVTPDRVTLTQPFLDITN--YDWTNG--VCILSVDKIAMTEGHM---------DSYMPRYLLGKEGFEHLDP--FVPIHVENYTDKEFHSYISYYLDRHWINK----TPQGFEEQLKF---MSNKNPYS-------LMQ--LVKAL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01163-1", "uniprot_id": "RT23_YEAST", "id": "Q01163-1", "name": "Small ribosomal subunit protein mS29", "aln": "-----MLRMSTSRFIGQRLFTTARSLQAAKPAPKGKTQGFSKKSSSVSSYSSAKRVTPGSLYKNWTNTTHTAQLQQTAVPLALPIFNFDDISKTLNKVVSYSNKQYKSLHHLGSFKKSQFNELFQKPVCLVREDATNSFLKKLVSHPVKKFIITGEPGVGKTVLLSQAHAYAVDSKQIIINISYPELFLNG-RNDFSYDDDLKLFIQPMYLKKLIRKILKANDPALLK-SIELSKDYKFSNANPKNASVKPFVTLNKTKNTVLDLLSVMTHPHNRGKLMKAIIDELSVQSKVPIMFTVDNFSKVLTTAYSAYRNTENKQIYSLDLQMGKLMMDIISGETKFANGESSTILAISGVDRTNKTLPVALGKIPVDPYVTRYHYEPKFVELLQKGNVTEFEVPKLNKQEVNELIDYYKQSNVLLDKDITGKKWENLIDEKYFLSGNGNPRE-------LLKSLVLSHR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : : . * . : *. .. : * :. : : :.. . : :: :* :: : :.::*. : .: .: *. :::: ** *.***: :.:. : . . :::::. . ::: : . : : *: : :: . * * .:: .:.* :.: :.. . : * . :: : . : : :. * . ::.::*... . :. : . : : : : .: . .: .* : ::. .*:.: : .: *: . : : : . :*... :.** : : : . . .. :* * : ", "identical_positions": 28, "similar_positions": 147, "identity": "6.0%" }, { "cls_id": "homologset.agr.MGI:1929596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K045-1", "uniprot_id": "A0A0G2K045_RAT", "id": "A0A0G2K045-1", "name": "", "aln": "MRSHPSLLLVYMGLATCLDTLPHREQSQVLDIFLDAPEAQSFLVGRRRFPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYAYNGKGGRGRVDVAGLAVGLTSGILLIVLAG-LGAFWYLHYRRRRLRVQESCLQ-ETGLIIPLS------PPTPLSPPPPP--GLPTYEQALAASGVHDAPPPPYS--SLRRPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R182-1", "uniprot_id": "TMG2_MOUSE", "id": "Q8R182-1", "name": "Transmembrane gamma-carboxyglutamic acid protein 2", "aln": "MRGRPSLLLVYMGLATCLDTSPHREQNQVLDIFLDAPEAQSFLVGRRRFPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYTYNGKGGRGRVDVAGLAVGLTSGILLIVLAG-LGAFWYLHYRRRRLRGQESCLQ-ETGLIIPLS------PQTPQSPPLPP--GLPTYEQALAASGVHDAPPPPYS--SLRRPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14669-1", "uniprot_id": "TMG2_HUMAN", "id": "O14669-1", "name": "Transmembrane gamma-carboxyglutamic acid protein 2", "aln": "MRGHPSLLLLYMALTTCLDTSPSEETDQ--EVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVASLAVGLTGGILLIVLAG-LGAFWYLRWRQH--RGQQPCPQ-EAGLISPLSPLNPLGPPTPLPPPPPPPPGLPTYEQALAASGVHDAPPPPYT--SLRRPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WF92-1", "uniprot_id": "X1WF92_DANRE", "id": "X1WF92-1", "name": "", "aln": "MLG---FSVICLSLLSLLHLVWGRVIYNENDVFLEEKSAGSFLS---RKLLYNSWDFEAVVPGNLERECIEEICSYEEAREVFEDDKKTAAFWKDYVNS-HQKLTEVDVAGLSAGIVAAVLVVVIATVLGVYCYKNRGKNARGGSVPVQMGEDGRPVPES--------VPLSGIVPA--GLPSYNEALTHSGQHDAPPPPYSGTTPTAPP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : :: :.* : *. . : ::** .* *** * * **:* :.********:** **:***** ***:. * **:.* . : .****.*:.*:...:*::*:* **.: * . :. . . * * * * .* . *. ***:*::**: ** ********: : * ", "identical_positions": 73, "similar_positions": 52, "identity": "34.76%" }, { "cls_id": "homologset.agr.MGI:1929597", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQG5-1", "uniprot_id": "BEAN1_MOUSE", "id": "Q9EQG5-1", "name": "Protein BEAN1", "aln": "----------------------------------------------------------------------MSFKRPC--------------------------------------------------PLARYNRTSYFYPTTFSESSEHSHLLVSPVLVASAVIGVVITLSCITIIVGSIRRDRQARIQRHHHRHRRHHHHHR-HRRRRHREY----ASGGHTHSRSSPRMPYACSPAEDWPPPLDVSSEGDVDVTVLWELYPDSPPGYEECMGPGATQLYVPTDAPPPYSMTDSC-------PRLNGALDSDSGQSRSHRQQE---QRTQGQSRLHTVSMDTLPPYEAVCG-TGSPSDLLPLPGPEPWPSNSQGSPIPTQAPMPSPERIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPW7-1", "uniprot_id": "A0ABK0LPW7_RAT", "id": "A0ABK0LPW7-1", "name": "", "aln": "PGPWRRRAETPEPRRRRGGPERVTVARAAARGRPGRGCCCCRAGQGRTRETAGGGGSPGNRGRGSVLPGPAGAPRPCTHSRPRRSGGTPQSSPSGGIRAGAGARVGPELEPKLEPALRRTERSAAAKPIARYNRTSYFYPTTFSESSEHSHLLVSPVLVASAVIGVVITLSCITIIVGSIRRDRQARIQRHHHRHRRHHHHHR-HRRRRHREYEQDHASGGHTHSHSSHRMPYACSPAEDWPPPLDISSEGEVDVTVLRELYPDSPPGYEECVGPGATQLYVPTDAPPPYSMTDSC-------LMLNGALDSNSGHSHSHHQQE---QRTHGQSGLHTVSMDTLPPYEAVCG-GGSPSDLLPLPGPEPRPSNSQGSLTPTQAPTPSPERIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3B7T3-1", "uniprot_id": "BEAN1_HUMAN", "id": "Q3B7T3-1", "name": "Protein BEAN1", "aln": "----------------------------------------------------------------------MSFKRPC--------------------------------------------------PLARYNRTSYFYP-TFSESSEHSHLLVSPVLVASAVIGVVIILSCITIIVGSIRRDRQARLQRHRHRHHRHHHHHHHHRRRRHREYEHGYVSDEHTYSRSSRRMRYACSSSEDWPPPLDISSDGDVDATVLRELYPDSPPGYEECVGPGATQLYVPTDAPPPYSLTDSC-------PTLDGTSDSGSGHSPGRHQQE---QRTPAQGGLHTVSMDTLPPYEAVCG-AGPPSGLLPLPGPDPGPRGSQGSPTPTRAPASGPERIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6F0-1", "uniprot_id": "E7F6F0_DANRE", "id": "E7F6F0-1", "name": "", "aln": "--MGLFSSLQAVLLHSPLVFTNSDIIKTSQIYSKAYENTIFLCKKEKVKVGTCLVNRLRCYYRKDCGREYMLMKLICS--------------------------------------------------VSSNQSSHAPEYPDCQEGGNEASLLVSPLVVAGIVIGLVLFLSCVTIIVGSLRKD--SRLRNPHLRAS--------------------YAPDGLSYGGSIGELRSTC--VEDFPPAFDFDSYVET-LSQVNVMYPDSPPHYDECVGQG-TQIYVPTDDPPPYSLTDPCRDQYMEDLPAGASWVSASGSSRYPSRLQNFRHQPVASISLSALPLDEAPPYEAVMSEQNQPLPLMPLDLLKHTTADSS-------AQDSVSHRIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: : : .*..:.: *****::**. ***:*: ***:******:*:* :*::. : * ... ::. * .: :* **:**.:*..* :. : : :****** *:**:* * **:***** *****:**.* ..: * ** * : : ::. .. * ::.:* ****** . . * *:** . . .*. * . ..**:", "identical_positions": 80, "similar_positions": 72, "identity": "20.46%" }, { "cls_id": "homologset.agr.MGI:1929600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7R2-1", "uniprot_id": "PMEPA_MOUSE", "id": "Q9D7R2-1", "name": "Protein TMEPAI", "aln": "---------MSPARAT----------AQRSLFPSMEITELEFVQIVVIVVVMMVMVVMITCLLSHYKLSARSFISRHSQARRRDDG-LSSEGCLWPSESTVSG-GMPEPQVYAPPRPTDRLAVPPFIQRS---RFQPTYPYLQHEIALPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLIDSTMLGGPCPPSSNSGISATCYSSGGRMEGPPPTYSEVIGHYPGSSFQ-HQQSNGPSSLLEGTRLHHSHIAPLE-----NKEKEKQKGHPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZNU8-1", "uniprot_id": "A0A8I5ZNU8_RAT", "id": "A0A8I5ZNU8-1", "name": "", "aln": "----MGVNGTAAAAAAGQPNVSCACNCQRSLFPSMEITELEFVQIVVIVVVMMVMVVMITCLLSHYKLSARSFISRHSQARRRDDGGLSSEGCLWPSESTVSG-GMPEPQVYAPPRPTDRLAVPPFVQRS---RFQPTYPYLQHEIALPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLIDSSMLGGPCPPSSNSGISATCYSSGGRMEGPPPTYSEVIGHYPGSSFQQHQQSNGQSSLLEGTRLHHPHIAPLE-----NKEKEKQKGHPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969W9-1", "uniprot_id": "PMEPA_HUMAN", "id": "Q969W9-1", "name": "Protein TMEPAI", "aln": "MHRLMGVN-STAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYKLSARSFISRHSQGRRREDA-LSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQ-HQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* *: .:**** ************::**********:*********************.***:*. **************** *:******************** **. ************* ***************************************************:**: ******************.************************* ****.* .**********.****** .***:*******", "identical_positions": 232, "similar_positions": 21, "identity": "80.0%" }, { "cls_id": "homologset.agr.MGI:1929601", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2S1-1", "uniprot_id": "NFIP1_RAT", "id": "Q5U2S1-1", "name": "NEDD4 family-interacting protein 1", "aln": "-------------MALALAALAAVEPACGTGYQQLQN----EEEPGEREQTAGDAPPPYSSISAESAAYFDYKDESGFP----------------------KPPSYN-------VATTLPSYDEAERTK----------------------AEATIPLVPGRD-----------EDFVGRDDFDDADQLR-----IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKW---------------------------------------ILIVRFSTYFPGYFDGQ----YWLWWVFLVLGFLLFLRGFINYAKVRKMPET-FSNLPRTRVLFIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BT67-1", "uniprot_id": "NFIP1_HUMAN", "id": "Q9BT67-1", "name": "NEDD4 family-interacting protein 1", "aln": "-------------MALALAALAAVEPACGSRYQQLQN----EEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFP----------------------KPPSYN-------VATTLPSYDEAERTK----------------------AEATIPLVPGRD-----------EDFVGRDDFDDADQLR-----IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKW---------------------------------------ILIVRFSTYFPGYFDGQ----YWLWWVFLVLGFLLFLRGFINYAKVRKMPET-FSNLPRTRVLFIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0W6-1", "uniprot_id": "NFIP1_MOUSE", "id": "Q8R0W6-1", "name": "NEDD4 family-interacting protein 1", "aln": "-------------MALALAALAAVEPACGSGYQQLQN----EEEPGEPEQTAGDAPPPYSSITAESAAYFDYKDESGFP----------------------KPPSYN-------VATTLPSYDEAERTK----------------------TEATIPLVPGRD-----------EDFVGRDDFDDTDQLR-----IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKW---------------------------------------ILIVRFSTYFPGYFDGQ----YWLWWVFLVLGFLLFLRGFINYAKVRKMPET-FSNLPRTRVLFIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DGP4-1", "uniprot_id": "NFI1L_DANRE", "id": "Q6DGP4-1", "name": "NEDD4 family-interacting protein 1-like", "aln": "----------------------MAEPSG--RYQQLPC----EEEPEAGPQVAADAPPPYSSIAADSAAFFDYKDDAAFP----------------------NPPSYN-------VATSLPSYDEAERTK----------------------TETSVPLVSGRD-----------DDFVARDDFEDADQLR-----IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKW---------------------------------------ILIVRFSTYFPGYFDGQ----YWLWWVFLVLGFLLFLRGFINYAKIRKMADS-FSTLPRTRVLFIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QQT7-1", "uniprot_id": "F1QQT7_DANRE", "id": "F1QQT7-1", "name": "", "aln": "----------------------MSDQRS--GYQQLTN----EEESAEGFQQTADAPPPYSSLGASNAAFFEYKEDEVYP----------------------KPPSYN-------VATSLPSYDEAERSK----------------------AEATVPLVTDRD-----------EDFIARDSFEDTDQLR-----VGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLVKW---------------------------------------VLIVRFSTYFPGYFDGQ----YWLWWVFLVVGFLLFFRGFVNYSRVRNMADHSMSTLPRTRVLFIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVJ5-1", "uniprot_id": "Q9VVJ5_DROME", "id": "Q9VVJ5-1", "name": "", "aln": "----------MPHNNQPSPGDDQLGPPKADFSAPPPY----EANVGHGQQVALPAQMPPLALATPDPSQIPIQMQVQLP----------------------SQADLMNAQLPPEIHGKLPTYEEVQMEKSLNGELPPAFLTLPSSQQLPPPPNPLLPPNPLRDGAAAVRSAQPALTFIAIDASDPENSLSTTDNLLGTDIMFITAFIVAFLFNWIGFLMLTCFCHTIAARYGALSGFGLSLAKW---------------------------------------TLIVKHSTDLASHEN------SWLWWLICAFGFLISIRALIQYVSIKRSWRL-LSASAQERLLFFY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38356-1", "uniprot_id": "BSD2_YEAST", "id": "P38356-1", "name": "Metal homeostatis protein BSD2", "aln": "MPEQELLIGQEMNTLHAGSSTDGINVGNAGRTRDTQTGVEGETEIGSDEEDSIEDEGSSSGGNSTTERLVPHQLREQAARHIGKIGRHFNILDRLFKKRTQQSSDIQQGAMFDGVFSNLSAKPDTTETEG--------------------NNEQDIPPTYDEAAADMAPSYYG-MDLNNSDIYYDEICIEG--LPVGNIANLLWNIIVSTSFQFIGFLITYILHTSHAAKQGSRFGLGLTFIGYGYSMIPNDVTSKVGKNKSLNRMELEDPNEFDDVRLNSQSTTQDKFESHLNHGLDEEKQNIPWLAVFVAFLGLFITLKSIYDYIQVKKLEKKYLNQSQNQA-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . . : . : . . .. : .*.: :. : : :* . : * : :*. :: :::: *::***:: : : *.: *: *:**:: : :..: : : ** .. .*::: ::.: :* ::. :. . ", "identical_positions": 18, "similar_positions": 68, "identity": "5.16%" }, { "cls_id": "homologset.agr.MGI:1929608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYW0-1", "uniprot_id": "AATF_RAT", "id": "Q9QYW0-1", "name": "Protein AATF", "aln": "-----MAELQPLALQLEQLLN-PRPREADPEADPEEATRARVIDRFDEGEE-EEDDLPVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWDQTLPSSSDNE--IPDEGGSEAGDSE--GLEELSED-----VEEDLEDNEIPDEGGSED--GDSEGL-EEEIS------------------EDVEEDLE---------GEDEEDREEDRNSEDDGVVMAFSGVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRYLVKG------TKPNAESEEISSEDDELVGE------KKKQRK-APPKRKLEMEDYPSFMAKRSADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHILMDKERLLRRTQTKRSAYRVL---------GKPEPVPEPVAETLPGEPES-----------LPQVPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TAMNDEARTELYRSLFGQLNRLDADHGQ------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKX4-1", "uniprot_id": "AATF_MOUSE", "id": "Q9JKX4-1", "name": "Protein AATF", "aln": "-----MAAPQPLALQLEQLLN-PRPREADPEADPEEATRARVIDRFDEGEE-EKDDLAVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWEQALPSSSDNE--ASDEGGSEDGDSEGLGLEEISED-----VDEDLEDNKISDEGGSED--GDSEGLGLEEFS------------------EDVEEDLE---------GEDEEDREEDRNSEDDGVVAAFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRHIVNG------AKPNTESEEISSEDDELVGE------KKKQRK-APPKRKLEMEDYPSFMAKRFADFTIYRNHTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHIMMDKERLLRRTQTKRSAYRVL---------GKPEPVPEPVAETLPGEPET-----------LPQGPANAHLRDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TAMSDDARTELFRSLFGQLNPPDADRGK------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY61-1", "uniprot_id": "AATF_HUMAN", "id": "Q9NY61-1", "name": "Protein AATF", "aln": "-----MAGPQPLALQLEQLLN-PRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEE--ISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHS--AKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPLFKDKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQYPDTRYLVDG------TKPNAGSEEISSEDDELVEE------KKQQRRRVPAKRKLEMEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHILMDKERLLRRTQTKRSVYRVL---------GKPEPAAQPVPESLPGEPEI-----------LPQAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TTMNDDARTELYRSLFGQLHPPDEGHGD------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R1W8-1", "uniprot_id": "F1R1W8_DANRE", "id": "F1R1W8-1", "name": "", "aln": "-----MAAS--ISQQLEDLLN-PLPHFVDPEDDQDEDTKAKVIEKFDEGGDENDEELLPGHLRKRSGAILADGDQRYRGKATSRKDLQKDLDGSADEDDDDNDDGVDDEDESGMLEKYMECMDDDDDNDDDDDDDDDDDDDDVEHQNDDDEDLVGDDGSQMSSLVSKMKGTDFMKLTEGLDDLGDSDEDEETAD-SEEEEGESDEGSEEEMEEEEESGLRTFSKEKVDEEVEKGRAVKNQLALWDLMLERRIKMQKALVTANQLPQP-QTFSEFKSRGGAEYADALKNSHKALKALQRSLLELQDLLLHQNKETRAISQGKTWGDGSSAKDDDEEINSEDDMDENEGDDQEVEQKAARNGPPKRKLEMADYPNFMAKRFAAFQPYRDTTLQKWYDKTRLTTGKNNKGFGAFDR---NILTQVEQVLMDKERLVRRTQTRRSEYRVL---------GKPEPVTPEIDNTISEGEVA-----------ELAVKANMHLKDLDENIFDDDDFYHQLLRELIERKTSATDPNDQVAMGKQWLAIQKLRSKIKKKVDTKASKGRKIRFHVHSKLMNFMAPMDN-SSMSDDARSELFRSLFANGPVTTQ----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM95-1", "uniprot_id": "AATF_DROME", "id": "Q9VM95-1", "name": "Protein Aatf", "aln": "MLRKSKKQPQTVAEKVSKLLAHPNESDSAEDSDFDVATGPRLVDFEE--EEYDLPDARSTDFRKRNVKLLSEQSDRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSEEETAAGHSESGEESEEIESNLTDFKKKFEAGDFKYDDD------------------EEEDDDSEEEDHSQESEGDDDDSEDDEAEDDAIKPSDVMSKTNHQAEIQKGLAVQNQLRIWERLLELRINTQKFTSKANQLPAP-ETLTKLASESD-ELQSVLNEAQERSSKLLQQLLSLQSALHQQYSEMKKSVKR------KQPTEDSG-------------------------------PAVKKFGSVLQSNFQQMIGYRNEVLLKWDDRTKLLTPGAGVKRKSLQED-YDIIKKIGSALANREALVEKSQTPKNSQAEQ---------QENTPVQR------------------------------------LKHIYDDSDFYHQQLRELIEYKASTS--SNMSEITKQFVELQKLRQKMKKKVDTRASKGRKLRYVVHNKLINFMAPNES-SDWTDASKSELYKSLFV-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06631-1", "uniprot_id": "BFR2_YEAST", "id": "Q06631-1", "name": "Protein BFR2", "aln": "-----------MEKSLADQISDIAIKPVNKDFDIEDEENASLFQHNEKNGESDLSDYGNSNTEETKKAHYLEVEK---SKLRAEKGLELN-----------------DPKYTGVKGSRQALYEEVSEN-----EDEEEEEEEEEEKEEDALSFRTDSEDEEVEID-------------------EEESDADGGE---TEEAQQKRHALSKLIQQETKQAINKLSQSVQRDASKGYSILQQTKLFDNIIDLRIKLQKAVIAANKLPLTTESWEEAKMDDSEETKRLLKENEKLFNNLFNRLINFRIKFQLGDHITQNEEVA------KHKLSKKR--------------------------------SLKELYQETNSLDSELKEYRTAVLNKWSTKVSSASGNAALSSNKFKAINLPADVQVENQLSDMSRLMKRTKLNRRNITPLYFQKDCANGRLPELISPVVKDSVDDNENSDDGLDIPKNYDPRRKDNNAIDITENPYVFDDEDFYRVLLNDLIDKKISNAHNSESAAITITSTNARSN-NKLKKNIDTKASKGRKLNYSVQDPIANYEAPITSGYKWSDDQIDEFFAGLLGQRVNFNENEDEEQHARIENDEELEAVKNDDIQIFG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . : : * : . :.: : : : .: : .. .* :.* . : * : . : .:: .:. : .. . : :.. : .:.. . .: . . : .** :: :* ::: ::: **: ** :*:** . : .. * *:: .: . * . *: :: : : . : . . . : ** .* ** :. : :. :: : : . *:.::: : ::**.***: *.:**: * * .: : :. .*::*::* :******:.: * . : .: ** .* *:: .*: ", "identical_positions": 49, "similar_positions": 133, "identity": "7.77%" }, { "cls_id": "homologset.agr.MGI:1929612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8N8-1", "uniprot_id": "A0ABK0M8N8_RAT", "id": "A0ABK0M8N8-1", "name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "aln": "--MLEKIPWNGASVQDLLG---------LENKKSGEVVAVKVFNSASYRRPPEVQVREFEVLRRLDHENIVKLFAVEETGGS-RQKVLVMEYCSSGSLLSVLEDPENTFGLPEEEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGKEGQSIYKLSDFGAARKLDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAISGTQKQENGPLEWSYSLPITCRLSVGLQSQLVPILANILEAEQAKCWGFDQFFAETSDILQRTVIHVFSLPQAVLHHIYIHAHNTIAIFLEAVYEQTNVAPKHQEYFF--EGHPCVLEPSLSAQHIAHTAASSPLTLFSMASDTPKGLAFRDPALDVPKFVPKVDLQADYSTAKGVLGAGYQALWLARVLLDGQALMLRGLHWVLVVLQNTCQQTLEITRTALLFLSSSLGTERLSSGAGMLDIQE------LKEATELRSRLQTFS-EVLSKCSHNVTETQRSLSCLVGELLKSRDQIHEDNRSIQKIQCCLDKMHFIYKQFKKSRMRPGLSYNEEQIHKLDKVNFSHLAKRLLQVFQEECAQTYQVSLVTHGKRMRQVQKAQNHLHLIGHSVATCNSEARGAQESLAKMFDQL--LLDRASKQGAEVSPQPMATHPGPDPKDLVFHMQELCNDMKLLAFDLQDNNRLIERLHRVPPTPEV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0T8-1", "uniprot_id": "IKKE_MOUSE", "id": "Q9R0T8-1", "name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "aln": "---MQSTTNYLWHTDDLLGQGATASVYKARNKKSGEVVAVKVFNSASYRRPPEVQVREFEVLRRLNHQNIVKLFAVEETGGS-RQKVLIMEYCSSGSLLSVLEDPENTFGLSEEEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLSDFGAARKLDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAISGTQKQENGPLEWSYSLPITCRLSMGLQNQLVPILANILEVEEDKCWGFDQFFAETSDILQRTVIHVFSLPQAVLHHVYIHAHNTIAIFLEAVYEQTNVTPKHQEYLF--EGHPCVLEPSLSAQHIAHTAASSPLTLFSMSSDTPKGLAFRDPALDVPKFVPKVDLQADYSTAKGVLGAGYQALWLARVLLDGQALMLRGLHWVLEVLQDTCQQTLEVTRTALLYLSSSLGTERFSSGAGMPDVQE------RKEATELRTRLQTLS-EILSKCSHNVTETQRSLSCLGEELLKNRDQIHEDNKSIQKIQCCLDKMHFIYKQFKKSRMRPGLSYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQTYQVSLVTHGKRMRQVQRAQNHLHLIGHSVATCNSEARGAQESLNKIFDQL--LLDRASEQGAEVSPQPMAPHPGPDPKDLVFHMQELCNDMKLLAFDLQDNNRLIERLHRVPSAPDV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14164-1", "uniprot_id": "IKKE_HUMAN", "id": "Q14164-1", "name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "aln": "---MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLRKLNHQNIVKLFAVEETGGS-RQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLF--EGHLCVLEPSVSAQHIAHTTASSPLTLFSTA--IPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLGAGYQALRLARALLDGQELMFRGLHWVMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSVAGTPEIQE------LKAAAELRSRLRTLA-EVLSRCSQNITETQESLSSLNRELVKSRDQVHED-RSIQQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKYQASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKGAQASPPPIAPYPSPTRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNRVPAPPDV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B651-1", "uniprot_id": "A0ACD6B651_DANRE", "id": "A0ACD6B651-1", "name": "", "aln": "---MTSTANYLWSQEDILGQGATANVYKARNKKTGELVAVKVFNLVSYNRPYEVQMREFEVLQLLNHVNIVKLFAVEEIISNPKQKILVMEYCSGGSLLNMLEQPEHAFGLPESEFLIVLHCVAHGMNHLRENSVVHRDIKPGNIMRQVGEDGRSVYKLADFGAARELEDDEKFVSIYGTEEYLHPHMYERAVLRIPQQKAYGVSVDLWSIGVTIYHMATGSLPFRPFGGPRKNKQMMHKITTEKPAGTIAGVQKEEDGPIEWRDKLPLSCQLSEGLKTQLVPVLANILLADDEKCWKFPQFFSATNDILNRITIYIFSLQQATTYSIYIQFHNTVSIFFEDVQAQTGIEPAAQQYLF--QGHPLILDPSMKVVNIPHTSSDKPMILISRRLERIIGYPFEEP--ESPPMPGKFDVVADFVFTKTIVKVIHQYLRIAYSLQEYRQFILQGFNSYIEQTSSEVIDVTHRISKVKMKLHSSISTEKTLHVFTQTFAHE------FPDFIDSKKKFPLIEAELQQMCGRGIREFQNILQYLRVTLSKHSETLAND-KSIQKMEVLLSQIVDVHFQYFRDRQTRKLGYNDEQIHKFEKLNLSSYLKKFKSLFKDDCFQKYLDVLNTTDRCSRALYDMQTHLDKFRDTLLQRIQDLKAHEILQNKVLERVVHRAVQQPVKAEVVDGKKKEEH-------MILKMTRLKSEMEAVAWELQKNNNMIESLSVVTPTMPVEKKNPQTNRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3Y8-1", "uniprot_id": "Q9V3Y8_DROME", "id": "Q9V3Y8-1", "name": "", "aln": "MSFLRGSVSYVWCTTSVLGKGATGSVFQGVNKITGESVAVKTFNPYSHMRPADVQMREFEALKKVNHENIVKLLAIEEDQEG-RGKVIVMELCTGGSLFNILDDPENSYGLPEHEFLLVLEHLCAGMKHLRDNKLVHRDLKPGNIMKFISEDGQTIYKLTDFGAARELEDNQPFASLYGTEEYLHPDLYERAVLRKSIQRSFTANVDLWSIGVTLYHVATGNLPFRPFGG-RKNRETMHQITTKKASGVISGTQLSENGPIEWSTTLPPHAHLSQGLKTLVTPLLAGLLEENREKTWSFDRFFHEVTLILRKRVIHVFFTNRTSSVEVFLEPDEQIDNFRERIFLQTEVPLEKQILLFNNEHLEKKVTPRTIAKAFPATTTDQPIFLYSND-DNNVQLPQQLDLPKFPVFPPNVSVENDASLAKSACSVGHECKRRVDIFTSMDILIKKGVEHFIEMLVTTITLLLKKTESFDNLLSTVIDYADVVHSMARVTKGDQEIKTLLTALENVKSDFDGAADVISQMHKHFVIDDELNDQWTS---SMHGKKCPCKTRASAQAKYLVERLRDSWQHLLRDRATRTLTYNDEQFHALEKIKVDHNGKRIKALLLDNVNPTVAQIAECLADWYKLAQTVYLKTQILEKDVRDCERKLNGIRDELYHVKSELKLDVDTKTINNNNQLAKIEERN-------RLRVMQQQQQEVMAVMRTNSDIISLLSKLGITNGSLESS---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:** ** :** ****.** *: ** :**:****.*: ::* *****:*:** . : *:::** *:.***:.:*:.**:::**.* ***:**. : **:***:* :****:******: :.::*:::***:******:*:*:: *.*:*********.:******* . *::: ..*********:** ***.*** **** *:*:: *::***:*.:*.*:*.* *:**:** .** .:** **:. :.*:**.:* : * * * :** .. **.: .:::* :: :::. .: : * * : ** : * :* : : * . :. *::..*: * * . . . * : :..: * :* . :: . : . :: :*.. : . . * : :. : : :. : : . : : : : . . . :: : : :.:: : :.* * **:**:* ::*::.. *:: :: :: . : : . : . .. . :: ..: : : * . . : : . ::. * . . ", "identical_positions": 178, "similar_positions": 208, "identity": "23.99%" }, { "cls_id": "homologset.agr.MGI:1929618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LE61-1", "uniprot_id": "A0ABK0LE61_RAT", "id": "A0ABK0LE61-1", "name": "StAR-related lipid transfer protein 3", "aln": "MSKLPGDLAG-DLERSLPALASLGTSLSHS-QSLSS-HFIPPPLEKRRV-------VSDVRRTFCLFVTFDLLFISLLWIIELNTN-TGIRKNLEQEVIHYSFQSSFFDIFVLAFFRFSGLLLGYAVLRLQHWWVIAITTLVSSAFLIVKVILSELLS--KGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQ-AAVARGPLLFSGALSEGQFYSPPESFAGSDSESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKLERRNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLVSYDVSSGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RIERRRD-RYLSSGIATTHCSKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLGATMFEFAFYLRQRVGELGARA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61542-1", "uniprot_id": "STAR3_MOUSE", "id": "Q61542-1", "name": "StAR-related lipid transfer protein 3", "aln": "MSKRPGDLAC-DLERSLPALASLGTSLSHS-QSLSS-HFIPPPLEKRRA-------ISDVRRTFCLFVTFDLLFISLLWIIELNTN-TGIRKNLEQEVIHYSFQSSFFDIFVLAFFRFSGLLLGYAVLRLQHWWVIAVTTLVSSAFLIVKVILSELLS--KGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQ-AAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVTGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFERSNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLVSYDVSSGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RIERRRD-RYLSSGIATTHCSKPPTHKYVRGENGPGGFIVLKSANNPRVCTFVWILNTDLKGRLPRYLIHQSLGATMFEFAFHLRQRVGELGARA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14849-1", "uniprot_id": "STAR3_HUMAN", "id": "Q14849-1", "name": "StAR-related lipid transfer protein 3", "aln": "MSKLPRELTR-DLERSLPAVASLGSSLSHS-QSLSS-HLLPPP-EKRRA-------ISDVRRTFCLFVTFDLLFISLLWIIELNTN-TGIRKNLEQEIIQYNFKTSFFDIFVLAFFRFSGLLLGYAVLRLRHWWVIAVTTLVSSAFLIVKVILSELLS--KGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQ-VAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLISYDVSAGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RIERRRD-RYLSSGIATSHSAKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLAATMFEFAFHLRQRISELGARA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DFS4-1", "uniprot_id": "STAR3_DANRE", "id": "Q9DFS4-1", "name": "StAR-related lipid transfer protein 3", "aln": "---MPSAVDYSELGGSLPAIASLNASYSQASLSLPSPYYCPLPPGERKA-------FSDVRRTFCLFVTFDLLFITLLWIIELNIS-KSIWNSLENEVVHYNFKSSFFDIFLLAVFRFLCLQLGYAAFRLRHWWVIAITTLVTTAFLIAKVILSDLFS--QNAFGYVLPITSFVVAWLETWFLDFKVLTQEAEDERVYLAAVNAACEPAPLICPRPVSDGQFYSPPESLAGSEDDLDEEGLGRRAVTEQEKAFVRQGREAMAVVEQILTQEENWKFEKTNELGDAVYTLEIPFHGKTFILKGLLQCTAELVYQEVILQPEKMVQWNRTVSVCQILQRVDDNTMVSYDVSAGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RVERRRD-CYISAGMATNHNSKPHHSRYVRGENGPGGFVVLKSSSNPSVCTFIWVLNTDLKGRLPRYLIHQSLAATMFEFMSHLRQRINEVHVSYR-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W145-1", "uniprot_id": "STRT1_DROME", "id": "Q9W145-1", "name": "Steroidogenic acute regulatory protein-like", "aln": "MSNMDPSDVR-STAQLILANARQGNSAYNMQYDMSRAHSINLITEDFLAGYMQDGRMSVVRRFFCLFVTFDLVFVSLLWLICIVINGDNIFTAFHKQIVEYTIYKSLFDVVAVAICRFLVLIFFYAILYINHWSIIALSTSGSCLFLISKVFVFDWLDSKQQVFEVILIITSFILAWGEAWFLDCRVIPQERHAQHYFRTMT--SNDRTPMEQPAILIEQ--ERPPQSVTDFYSLMDTARHSDE-EDELDDEYTQMGLDCLRKAYEIIESSD-WKVEKVNQKGDTIHSTQRDKIGKIYKLTARIKYPAKALMEDLFYRIEDCPKWNPALLESKIVRKINSYTDITYQVSVGGGGGMVKSRDFVNLRSCRLFYNGQICDDDETAQLSSDDGNSSLNRSCEGSVSTISDGDSNTPLLPSSVSSCKATFPTSSKGAAMPFDTLGNSLGAKSLGPIVNFDEEPPPLDQDEFEDAKDKVDGEANNMTKPNVPSVGKTKDRVWVTSAVSVQYAAVPPSPKYTRGQNIVSGFAFREIVGKSDSCIVEWVLCLDLKGYIPRYVLDAALTSSMTDYISNLRKHVNELRQKGRGRAPRTH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * . * : .:. : . . .* *** *********:*::***:* : . .* . :.::::.*.: .*:**:. :*. ** * : ** : :.** :**::* : *** **:: : :. : .* :* *.**::** *:**** :*:.** . :: : : : *: . : : **:*.:. . * . . : : : * :. . :*: ..: **.*: *: **:::: : ** : *. : .*: : :::: : * ** :: .:*:::::. * ::*:** *..**:*..*****:* : : :* ::::.::. : : * :*.**:* .** . : .:. * . *:* **** :***::. :* ::* :: **:::.*: ", "identical_positions": 115, "similar_positions": 161, "identity": "19.49%" }, { "cls_id": "homologset.agr.MGI:1929619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKK6-1", "uniprot_id": "NXT1_HUMAN", "id": "Q9UKK6-1", "name": "NTF2-related export protein 1", "aln": "-MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQASPSN--TVWKIASDCFRFQDWAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZV9-1", "uniprot_id": "NXT1_MOUSE", "id": "Q9QZV9-1", "name": "NTF2-related export protein 1", "aln": "-MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDDATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSN--TVWKIASDCFRFQDWAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ65-1", "uniprot_id": "B2RZ65_RAT", "id": "B2RZ65-1", "name": "NTF2-related export protein", "aln": "-MASVDFKTYVDQACRAAEEFVNVYYTTMDNRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQINVVDCQPVHDEATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSN--TVWKIASDCFRFQDWAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QCN6-1", "uniprot_id": "E9QCN6_DANRE", "id": "E9QCN6-1", "name": "NTF2-related export protein", "aln": "MSLTVDFRTQVDQSCRYSEEFINIYYECMDKKRRNLKRLYLDKATLVWNGNAVTGQEALGEFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVAAGSVKFEGNKQRFFNQNFLLTAQASPNSDQPVWKIASDCFRFQDWAN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3H8-1", "uniprot_id": "NXT1_DROME", "id": "Q9V3H8-1", "name": "NTF2-related export protein", "aln": "--MDSDLKAKVESCARTADTFTRLYYASVDNRRQQIGRLYLDNATLSWNGNGAIGRQMIESYFQELPSSNHQLNTLDAQPIVDQAVSNQLAYLIMASGSVKFADQQLRKFQQTFIVTAEN------DKWKVVSDCYRMQEV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::: *:...* :: * .:** :*::*: : ***:..*** ****.. *:: : .:*: ****:.*:..:*.**: ::*. .* : *:: .*:*** .:: * *:*.*::**: **:.***:*:*: ", "identical_positions": 48, "similar_positions": 57, "identity": "33.57%" }, { "cls_id": "homologset.agr.MGI:1929628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CBB9-1", "uniprot_id": "RSAD2_MOUSE", "id": "Q8CBB9-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "MGMLVPTALAARLLSLFQQQLGSLWSGLAILFCWLRIALGWLDP-GKEQPQVRGEPEDTQETQEDGNSTQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70600-1", "uniprot_id": "RSAD2_RAT", "id": "O70600-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "--MLVPTALAARLLSLFQQQLGSLWSGLAMLFCWLRIALGWPDP-GKGQPRVRGEPKETQETHEDPGSAQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGMEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGDYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRKWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFEAFLQRHKDVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSRSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WXG1-1", "uniprot_id": "RSAD2_HUMAN", "id": "Q8WXG1-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLLATKRRKQQLVLRGPDETKEEEEDP--PLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLDW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RH95-1", "uniprot_id": "RSAD2_DANRE", "id": "Q5RH95-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "MVTSNQLGFARLLMQLCVKNVQSFF---LALLRWLSMQVSGAHVQQTPARKISR-PESRTSKQKEGSRAPFTTPSSVNYHFTRQCNYKCGFCFHTAKTSFVLPIEEAKRGLRLLKEAGMEKINFSGGEPFVHQKGSFLGELVLYCKQELQLPSVSIVSNGSLIRESWFQKYGDYLDILAISCDSFIEETNQLIGRAQGRKSHLDNLHKVRNWCREYKVAFKINSVINTYNVEEDMTEQITALNPVRWKVFQCLLIEGENAGENSLREAEKFVISDQQFQDFLERHQSIQCLVPESNQKMRDSYLILDEYMRFLDCREGRKDPSKSILDVGVEEAIKFSGFDEKMFLMRGGKYVWSKADMKLEW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* *:.: : : *:: *: ** . : *.. . .:: . *** ****************************:******* ***:**:***********::::*.:**:** :** ** *************** **:.**:************ *:.* ****.**:*.*::**:*:*.***:*:********** :**:***.*:*.**.****************.**::*****:*:*.:::*: **:**:.:.**********:*************:* ******:********************** *****:*****:**:*", "identical_positions": 233, "similar_positions": 72, "identity": "64.19%" }, { "cls_id": "homologset.agr.MGI:1929645", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYJ4-1", "uniprot_id": "REC8_RAT", "id": "Q6AYJ4-1", "name": "Meiotic recombination protein REC8 homolog", "aln": "--MFYYPNVLQRHTGCFATIWLAATRGSRLVK--------REYLKVNVVKTCEEILNYVLVRVQPPMPGLP--RPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHILEHLHRA--------QLRIRID-MEEADLPSLLLPNCLAMMETLEDAPEPFFGTMSVDPTLPSPFDIPQIRHLLEAATPEKIREETLPEATPEPRKPDRTLAMVQSPEVITLQEAEPIRMLRIE----GEQDLPEISRGDLDLLIAE----EDDAILLEERQRGRLLRQRRASPPLDESKEEPRALEGDGLVSSLSPPAPAQVEGIREPLPDQAFPPEVQKMPGWEPGVLLTEVTPPQELRLPAPPSIEKRPPSPQRPPRRRRRGRQLL---FWDKETQISREKFEEQLQTGAHCCEYP--VVQPPKRKLMSPAELFRTPTLSGWLSPELLALWTHCAQVPPRMLRQRPQLETEETVEEERVADKEERRKTEALSEIEVLREAQEPSGPLMLSSELSLEVAEEEKSRTS-------------------FIPPEERWAWIE-------ERQPEPPALPMLPELPEVPMEMP----PGPELLSSEAVLRAVALELQANREPDFSSLVPPLS----------------SRKLASRVFYLLLVLSAQKILLVDQQKPYGRLLIRLGPKFP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5S7-1", "uniprot_id": "REC8_MOUSE", "id": "Q8C5S7-1", "name": "Meiotic recombination protein REC8 homolog", "aln": "--MFYYPNVLQRHTGCFATIWLAATRGSRLVK--------REYLNVNVVKTCEEILNYVLVRVQPPVAGLP--RPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHILEHLHRA--------QLRIRID-MEEADLPSLLLPNCLAMMETLEDAPEPFFGKMSVDPRLPSPFDIPQIRHLLEAATPEKTRKETLPEATPDPRKPDRTLATVQSPEVITLQEAEPIRMLQIE----GEQDLPEISRGDLELLIAE----KDDAILLEERQRGRLLRQRRASLPLDESREEPRALEGAGLVSALSPPAPAQVEGIQEALPGQVFPPEVQKMTGWEPGALLTEVTPPQELRLPAPPSTEKRLPSLQRPLPRRHRRRQLL---FWDKETQISREKFEEQLQTGAHCWEYP--VAQPPKRMLTSPAELFRTPTLSGWLPPELLGLWTHCAQVPQRMLRQRPQLETEETVEEERAADEEERRKTEALSEIEVLREAQEPSGPLMLSSELSLEAAEDEKSRTS-------------------LIPP-EWWAWSE-------EGQPEPPALPMLPELPEVPMEMP----PRPE-LSSEAVLRAVALKLQANKELDFSSLVPPLS----------------PRKLASRVFYLLLVLSTQKILLVEQQKPYGPLLIRPGPKFP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95072-1", "uniprot_id": "REC8_HUMAN", "id": "O95072-1", "name": "Meiotic recombination protein REC8 homolog", "aln": "--MFYYPNVLQRHTGCFATIWLAATRGSRLVK--------REYLRVNVVKTCEEILNYVLVRVQPPQPGLP--RPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRA--------QLQIRID-MET-ELPSLLLPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERV-EEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIE----GERELPEVSRRELDLLIAE----EEEAILLEIPR--------------------------------LPPPAPAEVEGIGEALG-----PEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVP--PPPRRRRRRRLL---FWDKETQISPEKFQEQLQTRAHCWECP--MVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRR--------ELPEEAAAE-EERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRIS-------------------LIPPEERWAWPE-------VEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSSLVSPLS----------------PRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLIQPGPRFH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TGX4-1", "uniprot_id": "A0AB32TGX4_DANRE", "id": "A0AB32TGX4-1", "name": "", "aln": "--MFYYPNVLQRHTGCFSTIWLAATKGIRISR--------RDYLKVNVRRTCEDIVDYVMVQVPPVHPSLP--RPRFSLYLSSQLQYGVIIVYHRQCAFLLEEVQQTIERLLRS--------KRHLNID-MPDNDRLVLNVPDSLFQLEEAEWALEPFFGVMGVD-CVPSPCLSSQQ--FMSASSPLTHTKEITSPKG-----------LVASPETITIKDAELVPVLAAEF---GGAELPEATAHEIDLLMEQ----QDQFHLEDEDKERERVADAEKSGSLDP-------------AMVSIEQLKNSECLMDEGNGRFTEVTLDRVALEMTPPPITMTTTTDASERDVEMESSETLTAEQSVPLKRRGRKRQLI---FADQNTQISQDAMRQQINNPLTETQSLSDVLQSIPASRKASAAVLLSTPCNLLIHPDLQTLWKSCSVSSTLSRPSRKRQAKKESELMEREKERGVERSRESSREVIRESEAALVLSESSAASDVPLDVSKGDRSPSD-------------------LITPNSRWSPIE-------EAP--VSMEVILEEHVDLPLGEA---ELEMSDIITEDLFRLITGFIECRGKVGFHSLLPPEA----------------DRSTVAHLFYQILELLCDLKLSAHQTEAFGVITFTTER----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12188-1", "uniprot_id": "REC8_YEAST", "id": "Q12188-1", "name": "Meiotic recombination protein REC8", "aln": "MAPLSLNFKDDKKYKGLTTVWLLSALGNSIVKESNNYYSNKSNSTGNISSSTVKKKDIVNISIPKTCDEIQNFENDFSLRYISNLLYGVTICYNKKTEYVLNDLNHLLVQLQKNDVYAFKAKNKSTRINGLNSNNSIIGNKNNNYTWEECVFFDDDPLYDITKVPALEFLNTTLQDNVSFIEEAKSIRRQDYINELSNSNRFELHGDMTNSDAQSNLGSNVRNSFPLDEIPVDVDFNLDLDDIVSHQGTPLGSHSSSQKDGNDFKFNYQGDELVLNFENDNENNSNGGEDTSVENEGPVANLKDYELGLEAQASEEENDLQQKLNTRMQRGHRADVGGQFSKVQFDAKTSYPNEVLKFNHGNYSHLMEKNRIRKLTGQNFLTSNISSLVRSCGEEEFFSTNWLSIFNDFSNIKTSEWDLYPQGFSSVERGRKRAHSLVSTQSSSSTRSHEYGRKSFRNNKNDNYSSDMENDNLLLNLEQINEDLEDGHYIEENSQGNILDFNLNLPPSSFGRSHTRNSTRSSGFNEDIVGALRRRVGPSEQNFAEEDDSSNSCFSDGSQQNLQQDKTNFQDVILDYQTKKFYDYIKERSIVVGRTTRSNPPFKRKMLLVDIIPSRMGEAQTGANFDDVERGVSRQIAASAFLSLLNLATKGMVKLNEYPVADAVTKDLKLRREDEIIVYA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: ::*:** :: * : : :. *: : . : * : : : . *** ::* ** * :: :::::::: : :* : : .*: : : : * :*::. * : ::. : . . . . : : . : :* : : * . :: : : * . . . : . .: * *:* * .: . :: . . : . : : . .* . .: . : : . : :: :: * :. :* . .. . :: : : :: : : * . : : .::.. * .: * :* * . : .: . : ", "identical_positions": 33, "similar_positions": 132, "identity": "4.85%" }, { "cls_id": "homologset.agr.MGI:1929646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJK4-1", "uniprot_id": "PEX3_RAT", "id": "Q9JJK4-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLRSMWNFLKRHKKKCIFLGTVLGGVYILG----KYGQKKLREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQ-QLNSESLTALLKNRP-----------------SNKLEIWEDLKIISFTRSIVAVYSTCMLVVLLRVQLNIIGGYIYLD--------------------------------------NATVGKNGTSILAPPDVQQQYLSSIQHLLGDG-LTELVTVIKQAVQRILGSISLKHSLSLLDLEQKLKEIRTLVEQHRS-CWNDKDASKSSLCHYMMPD---------EETPLAAQAYGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHG-------------------------------NSINSLSSVSLPLAKIIPIVNGQIHSVCSET------PSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXY9-1", "uniprot_id": "PEX3_MOUSE", "id": "Q9QXY9-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLRSMWNFLKRHKKKCIFLGTVLGGVYILG----KYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQ-QLNSESLTALLKSRP-----------------SNKLEIWEDLKIISFTRSIVAVYSTCMLVVLLRVQLNIIGGYIYLD--------------------------------------NATVGKNGTTVLAPPDVQQQYLSSIQHLLGDG-LTELVTVIKQAVQRILGSVSLKHSLSLLDLEQKLKEIRILVEQHQS-SWNDKDVSRSSLCQYMMPD---------EETPLAAQAYGLSHRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHG-------------------------------NSINSLSSVSLPLAKIIPIVNGQIHSVCSET------PSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56589-1", "uniprot_id": "PEX3_HUMAN", "id": "P56589-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLRSVWNFLKRHKKKCIFLGTVLGGVYILG----KYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQ-QLNSESLTALLKNRP-----------------SNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLRVQLNIIGGYIYLD--------------------------------------NAAVGKNGTTILAPPDVQQQYLSSIQHLLGDG-LTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSWINKDGSKPLLCHYMMPD---------EETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHG-------------------------------NSMNSLSSVSLPLAKIIPIVNGQIHSVCSET------PSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUL8-1", "uniprot_id": "Q9VUL8_DROME", "id": "Q9VUL8-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLSRLQDFLSRHRRKFIVTGVLVGGTIFAA----RYAQRRFVEFQEKQAREFFERTRRTTHFESTEKTCNQVILGMGEEMCQAVLR-ECSTDELLEQLRQNP-----------------KNKLELWEDMKIVAFTRLATYVYASSMLVIALRVQLNLLGGYIYRD--------------------------------------IMTEQKQ-----VTDELKQQYLSLIRHFITDSGIRDLARYIRTQVIAVTKTIPLSEQLSLSDLEQLFWSLQMAINADTR------RDPNSRMSKYLLPS---------QNP----------SHSPLLQKMVNETLDLLESEDAVGVCSHNVSRGFVLACDAIAESMGETLQHLPQAKVQTQQEQSVKFNQAGSLGASTSKSQNGLENNNLLNINRVLLALAKLIPIISGLTSRGFDTTSRPHNLPTQLLTFYVVAEKTKTLGANVYESFSSA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28795-1", "uniprot_id": "PEX3_YEAST", "id": "P28795-1", "name": "Peroxisomal biogenesis factor 3", "aln": "MAPNQRSRSLLQRHRGKVLISLTGIAALFTTGSVVVFFVKRWLYKQQLRITEQHFIKEQIKRRFEQTQEDSLYTIYELLPVWRMVLNENDLNLDSIVTQLKDQKNQLTRAKSSESRESSPLKSKAELWNELELKSLIKLVTVTYTVSSLILLTRLQLNILTRNEYLDSAIKLTMQQENCNKLQNRFYNWVTSWWSDPEDKADDAMVMAAKKSKKEGQEVYINEQAFLSLSWWILNKG-WLSYNEIITNQIEIEFDGIHPRDTLTLEEFSSRLTNIFRNTNSQIF------QQNNNNLTSILLPKDSSGQEFLLSQTLDADALTSFHSNTLVFNQLVNELTQCIESTATSIVLESLINESFHFIMNKVGIKTIAKKKPGQED-------------------------------QQQYQMAVFAMSMKDCCQEMLQTTAGSSHSG-----SVNEYLATLDSVQPLDDLSASVYSNFGVSSSFSFKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*.**: * :. . :.. . : :: : : * : : :.: : : :**..:. . .: : .: . : . :.: *:.. ..* *:*::::: :: : . .*: . *:: *:***:: * * : *. :* :** :: .. . * : : . *:* ::.. : .: : . . : ::*. .:. . :::** : :** * . :...* : :. . : . :. .: . :.: . : .. : : . :.*.**. *. . ", "identical_positions": 37, "similar_positions": 131, "identity": "7.64%" }, { "cls_id": "homologset.agr.MGI:1929648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIE9-1", "uniprot_id": "MED20_RAT", "id": "Q5XIE9-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSVQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHT-PGAPTVFG--------------NRHDAVYGPAD---TMVQYMELFNKVRK--------------QQQVP-------VAGIR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0X0-1", "uniprot_id": "MED20_MOUSE", "id": "Q9R0X0-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSLQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHA-PGAPTVFG--------------NRHDAVYGPAD---TMIQYMELFNKIRK--------------QQQVP-------VAGIR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H944-1", "uniprot_id": "MED20_HUMAN", "id": "Q9H944-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHT-PGAPAVFG--------------NRHDAVYGPAD---TMVQYMELFNKIRK--------------QQQVP-------VAGIR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBX1-1", "uniprot_id": "MED20_DANRE", "id": "Q6DBX1-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVCQVPVAEGKSVQQTVDLLHRKLEQLGAVKQGNFWVDCETYHATGN---ATGQPSKLLYVMHNSEAPLSCMALFEGGP----GLSADANFDVLMIKLKSHFQNAKGHKVESRGTRYRYCDFLVKIGT-VAMSSSARGISVEVEYCACVIPGDCWNLMKEFMQSFLGSNT-PELPTVFT--------------NKAEGLYVPVDCMDTMSQYLELFSKVRK--------------QQVLP-------GSGVR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91641-1", "uniprot_id": "MED20_DROME", "id": "P91641-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTILQPYPLPEGKSGAHIIDQLSKRLLALGATHAGQFLVDCETFISTPQP--HNGAPGRAVHVLHNSEYPASTFSIIDNGTGKQVAIVADNIFDLLMLKMTNTFTSKKQTKIESRGARFEYGDFVIKLGS-VTMMEHFKGILIEIEYKSCVILAYCWEMIREMLQGFLGIAVNKDFPSYFAPQTIMTAMGQQQLHAKHNDIFEPMD---TVKQYLEQFTNYRKHVTLMGGMGSGPGSQQVGPNVHMSPAVAGLHRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34162-1", "uniprot_id": "MED20_YEAST", "id": "P34162-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGKSAVIFVERATPATLTELKDALSNSILSVRDP----WSIDFRTYRCSIKN--LPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEAGEFETKIA--GIEGHLAEIR----------AKEYKTSSDSLG-PDTSNEICDLAYQYVR--------------------------ALEL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : : . : . : * . : : : :* .*: : . . .: :: : . . . : :... ** ::: . . . :.:: :. ::* .: :: : : : . . . .: : * . : . . . . * : : : : : ", "identical_positions": 10, "similar_positions": 67, "identity": "3.88%" }, { "cls_id": "homologset.agr.MGI:1929651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HC7-1", "uniprot_id": "SP20H_RAT", "id": "Q66HC7-1", "name": "Transcription factor SPT20 homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQALEQALDRAEYIVESAQQRPPKRKCLSSGRK------------------------------------------------------SIFQKLYDLYVEECEKEP-----EVKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLR-------------------------------------------GKNGSDS--------------ETIRLPYEEGELLEYLDAEELPPILVDLLEKSQVN--------------IFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLVCDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSVAVACTANRLLYNRQKMNTRPMKRCLKRYSRSSLNRQQD-LSHCPPPPQLRLLDFLQKRKER------------------KAGQHYDLKISKAGNCVDMWKRSPCNLAVPSEVDVEKYAKVEKSIKSDDSQPTMWP-----AHDVKDDYVFECEGGNQYQKTKLTILQSLGDP------------LYYGKIQPWKADEESDSQMSPSHSSADDHSNWFIIGSKTDAERVVNQYQELVQNEAKCPVKMSHSSSGSASLN------------------------------------------SGEEGE-PETSSIQSSVLGKGVKHRPPP-------------------------------------------------------------------IKLPSSSGNSSSGNYFTAQQASSFLKSPTPPPP------------------------------------------------------------------------------------------------------------------------------------------------------SSKPSLSRKSSVDLSQVSMLSPAALSPASSS--------------------------------------------------------------------------QRHES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT00-1", "uniprot_id": "SP20H_MOUSE", "id": "Q7TT00-1", "name": "Transcription factor SPT20 homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQAVEQALDCAEYIVESAQQRPPKRKYLSSGRK------------------------------------------------------SIFQKLYDLYVEECEKEP-----EVKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLR-------------------------------------------GKNGSDS--------------ETIRLPYEEGELLEYLDAEELPPILVDLLEKSQVN--------------IFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLVCDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSVAVACTANRLLYNRQKMNTRPMKRCWKRYSRSSLNRQQD-LSHGPPPPQLRLLDFLQKRKER------------------KAGQHYDLKISKAGNCVDMWKRSPCNLAVPSEVDVEKYAKVEESIKSDDSQPTMWP-----AHDVKDDYVFECEGGNQYQKTKLTILQSLGDP------------LYYGKIQPWKADEENDSQMSPSHSSADDHSNWFVIGSKTDAERVVNQYQELVQNEAKCPVKMSHSSSGSAALS------------------------------------------PGEEAEQAETSSIQSSVLGKGVKHRPPP-------------------------------------------------------------------IKLPSGSGNSSSGNYFTAQQASSFLKSPTPPP-------------------------------------------------------------------------------------------------------------------------------------------------------SCKPSLSRKSSVDLSQVSMLSPAALSPASSS--------------------------------------------------------------------------QRHES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEM7-1", "uniprot_id": "SP20H_HUMAN", "id": "Q8NEM7-1", "name": "Transcription factor SPT20 homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQALELALDRAEYVIESARQRPPKRKYLSSGRK------------------------------------------------------SVFQKLYDLYIEECEKEP-----EVKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLR-------------------------------------------GKNGSDS--------------ETIRLPYEEGELLEYLDAEELPPILVDLLEKSQVN--------------IFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFKRYSRSSLNRQQD-LSHCPPPPQLRLLDFLQKRKER------------------KAGQHYDLKISKAGNCVDMWKRSPCNLAIPSEVDVEKYAKVEKSIKSDDSQPTVWP-----AHDVKDDYVFECEAGTQYQKTKLTILQSLGDP------------LYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKCPVKMSHSSSGSASLSQVS---------------------------------------PGKETDQTETVSVQSSVLGKGVKHRPPP-------------------------------------------------------------------IKLPSSSGNSSSGNYFTPQQTSSFLKSPTPPPS------------------------------------------------------------------------------------------------------------------------------------------------------SKPSSIPRKSSVDLNQVSMLSPAALSPASSS--------------------------------------------------------------------------QRTTATQVMANSAG--------------------------LNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINLSGLLPSGGLLP--------------------------------------NALPSAMQAASQAGVPFG-----------------------------------------------------------------------------------------------------LKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALS-------------------------------------------------------AQQAAVINLTGVGSFMQ-------------------------------------SQAAVLSQLGSAENRPEQSLPQQRFQ------------------------------------------------------------------------------------------LSSAFQQQQQQIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTPKF------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKI6-1", "uniprot_id": "F1QKI6_DANRE", "id": "F1QKI6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQVLEYALDRAEYIVESARQRPAKRRVSSSGRK------------------------------------------------------SLYQKLYELYIEECEKEP-----ELKKLRRNVNLLQKLVSQESVSCLVVNLYPGNEGYSLMLR-------------------------------------------GKNGSDS--------------ETIRLRYEEGELLEYLDAEELPPILVDLLEKSQVN--------------IFHCGCVIAEVRDYRQSGNTKMPTYQSRHILLRPTMQTLICDVHAMTSD-HKWTQDDKLQLESQLILATAEPLCLDPSISVSCTTNRLLYNKQKMNTRSMKRCFRRHSRAALNRQQEIMSHCPALPQLRLLDYLQRRKER------------------KPAPSIDLKISKAGNCVDMWKQSSCQLTTPAEIDVEKYAVAENAAKLDDTQPTVWP-----AQDIRDDYTFECEMGGQLQRTKVTIFQSMGDP------------LVYGKIYSAK-----DSKLEEDVTDLHLIHPPFLIGSKTDADRFLMQYKEVYERDVKCQVKMLHNSQSQLSPS-------------------------------------------RENETDGFSALVQSSVLGKGVKHRPPP-------------------------------------------------------------------IKLPAGSACASSGNPYSTQASSGHLKCPTPPP-------------------------------------------------------------------------------------------------------------------------------------------------------SKNQSLSRKHSIELG---LLSPAALSPMQRSGTPKPSTPTPTNTPCSTPHPADVQSATPSVTPTPQDPTLPQPPT---------LLTPFAQQQMTLPVMTIPLPTSSTTSSQVMTNPAG--------------------------LNFINVVGSVCSPQTLMSGSNSMLGCSPGTLASG-IPLSGLLPSGGLMS--------------------------------------GTLP-AMQPAAPGGGPFG-----------------------------------------------------------------------------------------------------LNSSPGLRPLNLLQLPTGPLIFNSLQQQQFSP----QQQSSQSATSSPQQQGE--SADGGLTAEQGLS-------------------------------------------------------AQQTAVINLTGVGGFMS-------------------------------------PQAAVLSQLGCGLEGSGPSLPSPRLQ------------------------------------------------------------------------------------------QQHQPQIQLQFLQHQMQ-QQQMGMAVGAAAQAALPRP-HSANQPKSKRKRSTPQPLSKS-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU86-1", "uniprot_id": "SPT20_DROME", "id": "Q9VU86-1", "name": "SAGA complex subunit Spt20", "aln": "MQSLDSSCQEADFIINDTLKKLKGSSNADHVQGLAVHAHGSGVHQTQFVQYGTSGSSPQLQPQQSYHQLHPTLQQQQFASSSSKSYLETSLLQAIPQIPAQPPICIFDDDESPTEGTGGSLGSLLTEPTSATPSGLPTAIAPSPSSCSSSTTTMSNFNSITSPSPVVPDLLLSTPPGVNSSLSNSSTGAASVSSKKSEKRPPSANSTASGGGHHLHHHHLHQTHNHHVLASPTSSPSKRQKSNSSSKESSSSSRSSAIPAASVSTATSSSQSARAGAGAASSNSNSKPPSSVCQSGNSKFFNLHEKIRDLYLQLLSNDLNYFAETGLKQRTRSFTLERLVDREKLNTIVVNLYPGNKGYSLALHYDEHMVLNPQTNEWSPTDKDETSSDAAGLGTGTGSHRSRPKPLAQDESQSKTEAGHAKHDFGLVEVLRWPYENDLLLQCIDREMLPEFLMDLLVAETVSLSDGEGTRVYAKPSVFYAGCVIAQIRDFRQTFATSTNICDMKHILLRPTNATLFAEVQQMGSQ---LPAEDKLALESQLVLATAEPLCLEPDPSIGRQAINSQHQRQLYNSHELRRQMKKFTQTAINRKRK-LDQFTHHHGLELCDYLARLRQRPRTGSSSGGANATPATAPTNNPLVGAMLSSFTSKVPRRPHEVIRPIRPPTLEYPANLKVPEHVISVEKYAKAYEPLNEFSEACKDGCQPNCRHNFQPQLVEEYILETEREASEGRRALYHIKLSIFQRPSDAEYLGELYVDRDYREGERNGESCRFALGTRVHANRYIQQFREIFTEEGRKAVKITHLIPGHMPIVTHTGLTNEQRILLQQQQQQQQRQAQMQQQQQQQQQQVVVVANQQQQSQQQQQTQQAGQQLSATVHHVALPRQQITQKTLNLAGSNVINVQQNFRQQSAQQQQPQTYTIEAPQQQAAAQIVPQQQQQQQQQQQQHIHLQQLATGSSNTSTTTHQVSLSNGSLVLVQQQQPQQQSQQLAQALQHSGITIQPATIQQQQQQVKGTSVVGANSALRAQLNSNVPILQTQLKVQQQQIMQKQQQQQTTATSNNNNNNNNNNNMNNNTAIHPNPAINAIVNSIMNSANQYQQQQQQQHQQQHQQQTGNTSSNNNAAGSGGSTNNNGSSTSATTLKNSSNASILNLLNSAPAAMTSTPVASGTFTTSTGQQQPQTLTLVQHQQQSTPNTADAATATYVQTTRGTPTLVSTQRKQQSSEVLQNLLNANRKIGGGGTTTTTFRTNSAGNLIAVNLNQAGQSHHQQTGDGSQTVRVSMSALASQLASPPAVMTNPTTSYTVISSGNSAAAAAAWIQSPTGPVQQRILSSLRRDSTTAPPNAIVVGMAAPSPGSDSNASNASGFAVPNNLASTSSGGGGGGGALSALLTNAATPSPSGSDHSQSSQTHQNQALLERLSNVTSNVSAVSMPHMSPQQPQPTQQFITKTIVHSPATSSIHSPMSSPHPQPSASPQQQQQQQQQQTTATLNLQGINLSQLQGAMANFAGLQNVQVQIPGFTQPISLQFSGNSLQQQQSGNTATGAGTAQGQQRSVLVSVPVSSQQQQLPHTITLQTQSAPHHQQQHQQTQQQHAPPTGTIVSLPSSGPGTQTVVITNNSGGGVTAGSSTSGSAGGGGGSGATTAMLTLPIAQIVGAGVQKLNPQTIRTSNVGGGIGIAQQTVQQQTIQSQSGGNSTAAIQLLGTIQPRARNVQVVGTKQLANRQLITTQRQIGGSTLKIATTPVNAANVVTSSANLTTTPIVMSAQKLQLKTVKAPVQQQQQPQQQQQQLQQQHRILNQQSTATVSSQTLPSPNQVQVAQQQQQQQQQLQHIQIAGRATTASGAISQRTLTALAAAKQQQQQQQAAVNRRRSTTDATK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .::: *. . *.**: .*. * .:.:*: :**:: .:: * * . *::** :*.:. :********:**** *: .:: *:* *.:* **:. **: :* * ** :*:*** . *. :*:.*****::**:**: . : :******* **..:*: : *: . :*** *****:*********:*. :: : . :::* *:: ::* ::.:::::**::. :.: . *.* *:* : ::* . . :*. . * :. . *. :: . : :. .. : :. :*. :*. . * * .: *::: :. : : : . . . . * :*::..*:* : *::*: .: : **: * . . :: .. *. *:* . * :*.:.*. :*: . . .. : * * : . * * : . :*..*. : . . : ", "identical_positions": 124, "similar_positions": 185, "identity": "6.61%" }, { "cls_id": "homologset.agr.MGI:1929655", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q792Q4-1", "uniprot_id": "CRIPT_RAT", "id": "Q792Q4-1", "name": "Cysteine-rich PDZ-binding protein", "aln": "MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70333-1", "uniprot_id": "CRIPT_MOUSE", "id": "O70333-1", "name": "Cysteine-rich PDZ-binding protein", "aln": "MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P021-1", "uniprot_id": "CRIPT_HUMAN", "id": "Q9P021-1", "name": "Cysteine-rich PDZ-binding protein", "aln": "MVCEKCEKKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q567Z6-1", "uniprot_id": "CRIPT_DANRE", "id": "Q567Z6-1", "name": "Cysteine-rich PDZ-binding protein", "aln": "MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKMLTSKKARFDPYGKSGFATCRICKSSVHQSGSHYCQGCAYKKGICAMCGKKVIDTKNYKQTSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL77-1", "uniprot_id": "Q9VL77_DROME", "id": "Q9VL77-1", "name": "Cysteine-rich PDZ-binding protein", "aln": "MVCEKCEAKLSKVSAPNPWRT---STAPAGGRKINENKALSSARERYNPIG-TALPPCRICRQKVHQMGSHYCQACAYKKAICAMCGKKIMNTKNYKQSST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* **. * :*:.*: .*: :****:**** *:* : *::* * . :..****:..*** ******.*****.********:::******:*.", "identical_positions": 59, "similar_positions": 27, "identity": "58.42%" }, { "cls_id": "homologset.agr.MGI:1929657", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXE0-1", "uniprot_id": "HACL1_MOUSE", "id": "Q9QXE0-1", "name": "2-hydroxyacyl-CoA lyase 1", "aln": "MPESNSAEGSDRSEEQVSGAKVIAQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGYLTGRPGVCLVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACRLYTKFSARPSTIELIPFIIEKAVRSSIYGRPGACYIDIPADFVT----LQANVTSIKYKECCMPPPVSMAETSAVCAAASVLRDAKQP--LLIIGKGAAYSHAEDSIRKLVEQCSLPFLPTPMGKGVVPDNHPNCVGAARSRALQSADVIVLFGARLNWILHFGLPPRYQADVKFIQIDICAEELG-NNVRP--SVILLGDIDAVSKQLLEQFDKTP--WQCPPDSQWWKTLREKMKSNEAISKELASQKSLPMNYYTVFYHVQEQLPRD-SFIVSEGANTMDIGRTMLQNCLPRHRLDAGSFGTMGVGLGFAIAAALVAKDRSPGQRVICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDADTWEKMLHFQEAATTVPPMCLLPNSHYEQVMTAFGGKGYFVRTPEELQHSLRQALQDT---SKPCLLNIMIEPQSTRKAQDFHWLTRSNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CHM7-1", "uniprot_id": "HACL1_RAT", "id": "Q8CHM7-1", "name": "2-hydroxyacyl-CoA lyase 1", "aln": "MSESNSAEGSDRSEEQVSGAKVIAQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGYLTGRPGVCLVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACRLYSKFSARPSSIQHIPFVIEKAVRSSIYGRPGACYIDVPADLVT----LQESTTSIKYKECCMPPPLSLAETSAVRAAASVLRSAKQP--LLIIGKGAAYSHAEDSIRKLVELCNLPFLPTPMGKGVVPDNHPNCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQADVKFIQIDICAEELG-NNVRP--SVTLLGDVNAVSKQLLEQFVKNP--WQYPTDSKWWETLREKRKNNEAVSKELASKKSLPMNYYTVFYHVQEQLPRN-CFIVSEGANTMDIGRTVLQNYLPRHRLDAGSFGTMGVGLGFAIAAAVVAKERSPGQRVICVEGDSAFGFSGMEVETICRYNLPIIILVVNNNGIYQGFDADTWGKILNFQGTATTIPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQDSLRQALKDT---SKPCLINIMIEPQSTRKAQDFHWLTRSNI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJ83-1", "uniprot_id": "HACL1_HUMAN", "id": "Q9UJ83-1", "name": "2-hydroxyacyl-CoA lyase 1", "aln": "MPDSNFAE---RSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQP--LLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-NNVKP--AVTLLGNIHAVTKQLLEELDKTP--WQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLADT---TKPSLINIMIEPQATRKAQDFHWLTRSNM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39994-1", "uniprot_id": "PXP1_YEAST", "id": "P39994-1", "name": "2-hydroxyacyl-CoA lyase", "aln": "--------------MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKN--SHEIRRLVNTFNLPFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALAC----KASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE-----------KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.:: :** *:. .:: :**:****:.::* : ***:* ******.***** **::.:*** *:*.********.*: *: * ***:**.***.:.: *.***: **. : **:.: : : * :: :**:. .* * .*..*:*:***:: *: . : : :.* :. .:.* : ...:: . *: *::*****. ...*::**: .********.**:***. * *.:***:**: **:::::*********** .*:::.: ***.* .* ** *** * : : *:: . *:*:: : *: * : :*** : *:: . . :. :** *: :: : ::*:********.* : . **:*****: .***:***:*:*. * * :: ::********.**:** * :*.::::*:**.***:* : :** .* *.:*: * ..:*.:.:**.* .**. .::*:: : :..::*::*** . :* * * .:..:", "identical_positions": 208, "similar_positions": 194, "identity": "34.9%" }, { "cls_id": "homologset.agr.MGI:1929658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7D3-1", "uniprot_id": "D4A7D3_RAT", "id": "D4A7D3-1", "name": "Serine/threonine-protein kinase TBK1", "aln": "---MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPLSCSLSQGLQALLTPVLANILEADQEKCWGFDQFFAETSDVLHRMVIHVFSLQHMTALKIYIHSYNTAAVFHELVYKQTKIISSNQELIYEGRRLVLELG--RLAQHFPKTTEENPIFVTSREQLN-SIGLRYEKISLPKIHPRYDLDGDASMAKAVTGVVCYACRTAGTLLLYQELMRKGVRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKVSLDAAELGEISDIHTKLLRLSSSQGTIESSLQDINSRLSPGGSLADTWA---HQEGTHPRDRNVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVRKYEAFKDTSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQKMLAASSGIKHTVAPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUN2-1", "uniprot_id": "TBK1_MOUSE", "id": "Q9WUN2-1", "name": "Serine/threonine-protein kinase TBK1", "aln": "---MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPLSCSLSQGLQALLTPVLANILEADQEKCWGFDQFFAETSDVLHRMVIHVFSLQHMTAHKIYIHSYNTAAVFHELVYKQTKIVSSNQELIYEGRRLVLELG--RLAQHFPKTTEENPIFVTSREQLN-TVGLRYEKISLPKIHPRYDLDGDASMAKAVTGVVCYACRTASTLLLYQELMRKGVRWLVELVKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKVNLEAAELGEISDIHTKLLRLSSSQGTIESSLQDISSRLSPGGLLADTWA---HQEGTHPRDRNVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMSHFSEECVRKYEAFKDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQKMLAASGGVKHAMAPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHD2-1", "uniprot_id": "TBK1_HUMAN", "id": "Q9UHD2-1", "name": "Serine/threonine-protein kinase TBK1", "aln": "---MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPG--RLAQHFPKTTEENPIFVVSREPLN-TIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWA---HQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQKMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3Y8-1", "uniprot_id": "Q9V3Y8_DROME", "id": "Q9V3Y8-1", "name": "", "aln": "MSFLRGSVSYVWCTTSVLGKGATGSVFQGVNKITGESVAVKTFNPYSHMRPADVQMREFEALKKVNHENIVKLLAIEEDQEGRGKVIVMELCTGGSLFNILDDPENSYGLPEHEFLLVLEHLCAGMKHLRDNKLVHRDLKPGNIMKFISEDGQTIYKLTDFGAARELEDNQPFASLYGTEEYLHPDLYERAVLRKSIQRSFTANVDLWSIGVTLYHVATGNLPFRPFGG-RKNRETMHQITTKKASGVISGTQLSENGPIEWSTTLPPHAHLSQGLKTLVTPLLAGLLEENREKTWSFDRFFHEVTLILRKRVIHVFFTNRTSSVEVFLEPDEQIDNFRERIFLQTEVPLEKQILLFNNEHLEKKVTPRTIAKAFPATTTDQPIFLYSNDDNNVQLPQQLDLPKFPVFPPNVSVENDASLAKSACSVGHECKRRVDIFTSMDILIKKGVEHFIEMLVTTI-TLLLKKTESFDNLLSTVIDYADVVHSMARVTKGDQ------EIKTLLTALENVKSDFDGAADVISQMHKHFVIDDELNDQWTSSMHGKKCPCKTRASAQAKYLVERLRDSWQHLLRDRATRTLTYNDEQFHALEKIKVDHNGKRIKALLLDNVNPTVAQIAECLADWYKLAQTVYLKTQILEKDVRDCERKLNGIRDELYHVKSELKLDVDTKTINNNNQLAKIEERN--------RLRVMQQQQQEVMAVMRTNSDIISLLSKLGITNGSLESS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.: .::* :.:**:***..**:* :* **: *:*.** *.:**.********.***:**:*****:****: * **::**:*. ***:.:*::*.*:***** ***:**..: .**:***:* :****:******:.*.****::**************:: *.************:********. *:.: *.*****:***:**.***.****** * *:*:*.*::* * *.**.***.* :*****:** :* . **:**:.*:**:**.:** ::** *.**:** *.: :*:: ***** :: :: ::::.. : *:* :: **:: .:* *:::..:* : :*: ** ** ::***: *.: * : : .:* . *. .::.***:**: .* . * .. : : *::**:. ::*:: : **** . .* : : ..*: :: * . **. : * * .:.*. . :.:: .:: .. * * *: * : : * : : *:: : : : :: :*:* * *:**:**:* ::* *: ::..: : : :: . : : :* : : : * :: * *.::. :: .::. * .: : : . :: :: * . :: :::: : *: : *..*:. :..* : .* : . ", "identical_positions": 257, "similar_positions": 255, "identity": "34.82%" }, { "cls_id": "homologset.agr.MGI:1929666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40890-1", "uniprot_id": "VTH2_YEAST", "id": "P40890-1", "name": "VPS10 homolog 2", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICD-KSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFN---SSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVR-LGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTSRTDLLG----ASNIPDALPARS--ASHESDLAAARSEDK------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40438-1", "uniprot_id": "VTH1_YEAST", "id": "P40438-1", "name": "VPS10 homolog 1", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICD-KSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFN---SSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVR-LGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTLRTDLLG----ASNIPDALPARS--ASHESDLAAARSEDK------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53751-1", "uniprot_id": "YN94_YEAST", "id": "P53751-1", "name": "Uncharacterized membrane glycoprotein YNR065C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIP--YDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKG-TFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCGESDYECSFEFVRDANGLCIPDYNLIAFSNICD-KSKDKSVLVEPLQLIKGDECKTPMKIEPVDIPCDEIPEEGSSDREIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTNGEKIVEVVFNPYFN---SSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKKSSETRSLVSSIDFFQGDNKIIFENIIGYLSTGGYIIVAVPHEDNELRAYVTIDGTEFAEAKFPYGQDVSKQEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNREKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDKLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGKKRADFKYSPLGSRTGCLFGHQTEFLRKTDEKCFIGNIPLSEFSRNVKNCSCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVR-LGLCISLITKSAFQRTKAGVARFSSKLRARFGNRKGPTYSSLLQGQFSDESD----GLHEDANDLSSFTSQDSNFEIEQEDAYRPEQEHTSQIDQPA----TSNIPDALPARS--AIHKPDSTAVRNEDE------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32319-1", "uniprot_id": "VPS10_YEAST", "id": "P32319-1", "name": "Vacuolar protein sorting/targeting protein VPS10", "aln": "MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDDSNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINFYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKSKGVTKISVDNGLTWTMLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIP--YNADEDDDPQSEFYYSLDQGKTWTEYQL---ETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTN-------FIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQ--LFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCD-KTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYYN---SSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLGSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVK-SGFYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPT----TTDVPDTLPEGNEENIDRPDSTAPSNENQ------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25657-1", "uniprot_id": "YCY9_YEAST", "id": "P25657-1", "name": "Uncharacterized protein YCR099C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSIFLLHFDYKTCEEEDFEDWNLADGKCLNGAKYMYKRRKQDARCLVKRTFKDMI--LHEIPCDSCTESDYECSSEFVRDAKGDCIPDYDQIALSDICD-KANGETVSLEPLQLIKGDKCKKPMEIEAMNIPCEKILRESSNGKKIATIENKFDFEI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9JLC4-1", "uniprot_id": "SORC1_MOUSE", "id": "Q9JLC4-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-VGAGDGSSAGLSALLAGAGLLMLLAPGVCSSLSCCPPQHPSSTPRRTLTPRGFPHPGPLGRAPA----------------------TPPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATAARSGR-----RRRSGTEPEKIE-----------PGEGASRSRRDMLKDGGQ-----QGLGTG-----------------ARDPGKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK---CKIMLLTDPEIESSLLISSDEGATYQKYRLNFYLQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQESVVPNRFYWSVMGSSKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGGRPHYYVSYRRSPFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYN--LYISDTRGVYFTLALENVRSSRGPEGNVMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDA-------DLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASRDTAPSIIVASGNIGSELS--------DSDISMFVSSDAGNTWR------QIFEEEHSILYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQG--------EACIMGAKRIYKKRKSERKCMQ--KYAGAMESEPCVCTEADFDCDYGYERHSNGQ-------CLPAFWFNPSSLSKDCSLGQSYLNSAGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGI-AVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPS---------------------QVGTLTYVWWYGNNTEPLITLEGSISFKFTSEGMNTITVQVSAGN---AILQDTKTIAVYEEFRSLRLAFSPNLDDYNPDIPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGTRENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVA----------------LPSPPSPS-AQPGDSSLRLQRPR------------PATPPSSPKRGS---AGAQFAI------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEA1-1", "uniprot_id": "A0A8I6AEA1_RAT", "id": "A0A8I6AEA1-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-VGAGDGSSAALSALLTGAGLLMLLAPGICSSLSCCPPQHPSSTPRWTLTPRGFSYPGPLGRAPA----------------------TPPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATASRSGR-----RRRSGMDPEKTE-----------PGEGTSRSRRDMLRDGGQ-----QGPGTG-----------------ARDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK---RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEAVVPNRFYWSVLGSNKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGGRPHYYVSYRRNPFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYN--LYISDTRGVYFTLALENVQSSRGPEGNVMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDA-------DLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASRDTAPSIIVASGNIGSELS--------DSDISMFVSSDAGNTWR------QIFEEEHSILYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQG--------EACIMGAKRIYKKRKSERKCMQG-TYAGAMESEPCVCTEADFDCDYGYERHSSGQ-------CLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGI-AVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPS---------------------QVGTLTYVWWYGNNTEPLITLEGSISFKFTSEGMNTITVQVSAGN---AILQDTKTIAVYEEFRSLRLAFSPNLDDYNPDIPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGARENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGINVYAQMQNEKEQ-ELINPVSHTESRPTAPHPDLRRPGQLVDEKVESHLLDQDKPHHLHRQSGDLLGHNLQSKENPQRLQETC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WY21-1", "uniprot_id": "SORC1_HUMAN", "id": "Q8WY21-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-VGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPA----------------------TPLPLVVRPLFSVAP-GDRALSLERARGTGASMAVAARSGR-----RRRSGADQEKAE-----------RGEGASRSPRGVLRDGGQ-----QEPGTR-----------------ERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK---RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYN--LYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDT-------DLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSELS--------DTDISMFVSSDAGNTWR------QIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQG--------EACIMGAKRIYKKRKSERKCMQG-KYAGAMESEPCVCTEADFDCDYGYERHSNGQ-------CLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGI-AVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPS---------------------QVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAGN---AILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLP-YQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVA----------------LPSPPSPS-TQPGDSSLRLQRAR------------HATPPSTPKRGS---AGAQYAI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN08-1", "uniprot_id": "A0A8M9PN08_DANRE", "id": "A0A8M9PN08-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERGIRYCRVHVRAFCTLLLILFAWVPVAETVITCRSCHLLDKWSGRELLVKMDSGVDS-GKVGDQDG----------------------DGSLFNLAGAETGQPDCGASDSGEHAHSVRKRNTESLRSGKTPPDEKWKSMRSHDKVYNLKLAASRATAPGDPHHRVRRGTQEPGSPPGARFQPLGFGNVTARAARRVPRSELRWNRDERRTAASRQEELKLTSSTFALTGDSAHNQAMVHWSGQNSSVILMLTKLYDFNLGSVTESSLWRSTDYGTTYEKLNEKVGVKTILSYLYVSPNNK---RKIMLLTDPEVESSLLISSDEGATYQKYRLNFYILSLLFHPEQEDWILAYSHEQKLYSSVEFGRRWQLVHERVAPNRFYWSKTGLDKEPGLIHLETSISESQALYVTCKLQNCTDANKGKPFPGYIDPNSLVVQDEYVFVQVSTGGRPIYYVSSRRDVFTPMKLPKYTLPKDLHVISTDENRVVAAVQEWNQNDTYN--LYVSESGGIYYTLALENVMSSMGPEGNVMIDLYEVAGIKGMFLANKKLNNEVKTYITYNKGRDWRLLQAPSA-------DLRGNRIHCMLPYCSLHLHLHVSANPYTSGNIASRESAPGIILASGSIGAELT--------SSNVSMFITSDAGNTWR------QIFDEEYSVLYLDQGGALVAIRHTPLPIRHLWLSFDEGRVWNKYSFTSSPLFVDGVLGEPGEETLIMTIFG-HVSHRSEWQLVKIDFRSIFNRRCVESDYVPWDLHDQG--------ERCLMGVKRVYRKLKATARCVMGKTYSVTMISEPCHCTESDFECDYGFERRTDGK-------CTPAFWFPPSSMSRTCTTEHTFLNSTGYRKVVSNNCTGGVIERYTARRQLCPSQAPRGLHLVTSEGKLTATLASNVTFLVFLEEGDGSKTSITVDFGDGN-AFTYSNVSSIEDGIKHIYKTVGIYRVSATAENSLGSETVLLFLHVTCQLDSIHLSAPFVAVKNKEVNLTVVLYPS---------------------QVGTVTYIWWFGNNSEPVITLDGSVSFTFSREGISIVTVQVSAGN---NILQDRKTIAVHEYFRSHLLAFSSNLDDHNPDVAEWRLDVSRVIKTSMMQATGVSPDLLLVTVLPGLPTAAEFFLLPDKQLTEGKPDKTATHLDQLSEVVLSALNQNLVQFTLRPGVQITVYAAHLSAAPLVDTSENHSGSAMLMLLSVVVLGLAIFLIYKFKRKIPGLHVYAAMQDEKEQEMIQSPVSPTDSTPSSSSQRELLTS------------LEPLDTEPNTQTIECIKPHPRVKFSSDLPTYIDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: *: : * ...:: : : . :: : . * : :: * :.. * .: :*: .*.. : . :. : . . :: . ", "identical_positions": 8, "similar_positions": 39, "identity": "0.5%" }, { "cls_id": "homologset.agr.MGI:1929668", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI90-1", "uniprot_id": "RNF14_MOUSE", "id": "Q9JI90-1", "name": "E3 ubiquitin-protein ligase RNF14", "aln": "MSAEDLEAQEDELLALASIYDADEFRKAESVQGGETRIYLDLPQNFKIFVSGNSNESLQNSGFEYTICFLPPLVLNFELP-PDYPSSS-PPSFTLSGKWLSPTQLSALCKHLDNLWEEHRGRVVLFA-WMQFLKEETLTYLNIVSPFELKMGSQKKVQRRATAQASSSTELGVGGAAAADVDQEETVDERAVQDVESLSSLIQEILDFNQARQTKCFNSKLFLCSICFCEKLGSDCMYFLECKHVYCKACLKDYFEIQIKDGQVKCLNCPEPQCPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVYCP------RPCCQLPVMQEPGGTMAICSSCNFAFCTLCRLTYHGLS-PCKVTAEKLIDLRNEYLQ---ADEATKRFLEQRYGKRVIQKALEEMESKDWLEKNSKS-------CPCCGTPIQKLDGCNKMTCTGCMQYFCWICMGSLSRANPYRHFTDSESPCFNRLFHAVDINGDMWEDEIEEDDDDEDDDDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBS8-1", "uniprot_id": "RNF14_HUMAN", "id": "Q9UBS8-1", "name": "E3 ubiquitin-protein ligase RNF14", "aln": "MSSEDREAQEDELLALASIYDGDEFRKAESVQGGETRIYLDLPQNFKIFVSGNSNECLQNSGFEYTICFLPPLVLNFELP-PDYPSSS-PPSFTLSGKWLSPTQLSALCKHLDNLWEEHRGSVVLFA-WMQFLKEETLAYLNIVSPFELKIGSQKKVQRR-TAQASPNTELDFGGAAGSDVDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCP------RPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVS-PCKVTAEKLMDLRNEYLQ---ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKS-------CPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RB95-1", "uniprot_id": "RNF14_DANRE", "id": "F1RB95-1", "name": "E3 ubiquitin-protein ligase RNF14", "aln": "MS-ADQEAKEDELLALASIYDEEEFHRAESGKEGEIHLCLELPPNFKLLVKG------QKS-AEHNISFLPPLVLSFDLP-DDYPSTS-APIFTISSKWLTRVQITALCRKLDELWEENQGNVVLFT-WIQFLKEETLDFLGIQSPLEIQRSG---------SQPQCEPAQKHAADASGEKSKVQDLDPRAVQEVDAQTDILTQLLDFDEAQKQRVFDGKAFCCGICYSEKLGCDCLLFKECEHVYCKACIKEYFQIQIKDGKVQCLNCPEPKCASTATPTQVKLLVGEDEFARYDRLLLQSSLDLMADVVYCP------RMSCCMAVMVEPDSTMGICPSCRYAFCTLCRRSYHGLS-HCIATADELRSLRDEYLS---SSEEGKKFLEKRFGKRVIQRAVEESFSTDWLKTNCKQ-------CPCCGTNIQKAHGCNKMTCSSCQKYFCWICLGALSRVNPYSHFNNPDSPCYNQLFHGMEMEEDEAFGSDEDD---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04638-1", "uniprot_id": "ITT1_YEAST", "id": "Q04638-1", "name": "E3 ubiquitin-protein ligase ITT1", "aln": "---MALTQFENDLEILRDMYPELEMKSVKVEEEGEFPQRINGKLLFKISLLADVN--IEFGEQHMLLSNLSNECVEFTIYSCHYPDIRRCVVMDIKSLWISTDEKKMLIDKALRLVEETVDMSIEFADSFTSILILIFGFLIDDTAILLFPNG----IRKCLTQDQYDLFKQISEEATLQKVSRSNYHCCICMEMEKGVRMIKLPCENANVEHYLCRG----CAKSYFTAMIQENRISSVRCPQCEYKELKLEDFKSYKK--MLKALFTP------LIPVSFLKEVIDTELCERYEKMFYNQAATRLS--KYCPYACVTCRRCDSWCTKEDLDDAMIQCQKCHFVFCFDCLHAWHGYNNKCGKKVSLSTDIIEEYLDDTVTSYERKRKLEAKYGRRVLELEVNDYLAEKMLDLAIKKEGSNLQRCPKCKVVVERSEGCNKMKCEVCGTLFCFICGVLLYPEDPYEHFREAYSGCYGRLFEGMPGTET------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::* * .:* *:: .: : ** :: **: : . : . . :. *. :.* : .**. : :.. *:: : . * : .* ** . : *: : : : :* :.: : .. :* . . . * : . . . ::: :: : :..: . . : : : : .* : * : *: : ::.* * . :* :: : **:::: :.: :: *** * . . : . :* * .*.:.** * ::** . * ... .: :***. :. *: *: ::*:**:: ::: : . *. *. ** * . ::: .*****.* * **:** * :** ** :. * *:.:** .: ", "identical_positions": 76, "similar_positions": 144, "identity": "15.05%" }, { "cls_id": "homologset.agr.MGI:1929671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M971-1", "uniprot_id": "AF1Q_RAT", "id": "Q5M971-1", "name": "Protein AF1q", "aln": "MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDSPTYKSKESNSIGKMGGQATGAER-KSPEGDPLLEYSTFNFWRAPIASIRSIDLDLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97783-1", "uniprot_id": "AF1Q_MOUSE", "id": "P97783-1", "name": "Protein AF1q", "aln": "MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTPTYESKDSSSVGKMNGQASGTEQ-KNPEGDPLLEYSTFNFWRAPIASIHSVDLDLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13015-1", "uniprot_id": "AF1Q_HUMAN", "id": "Q13015-1", "name": "Protein AF1q", "aln": "MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTATYKVKDS-SVGKMIGQATAADQEKNPEGDGLLEYSTFNFWRAPIASIHSFELDLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQS5-1", "uniprot_id": "AF1Q_DANRE", "id": "A3KQS5-1", "name": "Protein AF1q", "aln": "MLDKTSSQFDSFLFWRQPIPSLDLSELEDLGISAP---KSKEMKSTKSFPRQDEDEDR----E---LSKFSTFNFWKEPIPSIDTLDFSLLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .***:.****** ***.*******.**:* . : *: * .: * :: * * ::******: **.** :.::.** ", "identical_positions": 41, "similar_positions": 22, "identity": "44.57%" }, { "cls_id": "homologset.agr.MGI:1929676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R416-1", "uniprot_id": "PKR1_RAT", "id": "Q8R416-1", "name": "Prokineticin receptor 1", "aln": "METTVGTLGENTTNTFTDFFSARDGSGAETSPLPFTFSYGDYDMPSDEEEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFITALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAAGLIFLVWSVSILIAIPAAYFTTETVLVIVESQEKIFCGQIWPVDQQFYYRSYFLLVFGLEFVGPVIAMTLCYARVSRELWFKAVPGFQTEQIRRRLRCRRRTVLGLVCVLSAYVLCWAPFYGFTIVRDFFPSVFVKEKHYLTAFYVVECIAMSNSMINTLCFVTVRNNTSKYLKRILRLQWRASPSGSKASADLDLRTTGIPATEEVDCIRLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKL1-1", "uniprot_id": "PKR1_MOUSE", "id": "Q9JKL1-1", "name": "Prokineticin receptor 1", "aln": "METTVGALGENTTDTFTDFFSALDGHEAQTGSLPFTFSYGDYDMPLDEEEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFITALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAAGLIFLVWSVSILIAIPAAYFTTETVLVIVERQEKIFCGQIWPVDQQFYYRSYFLLVFGLEFVGPVVAMTLCYARVSRELWFKAVPGFQTEQIRRRLRCRRRTVLGLVCVLSAYVLCWAPFYGFTIVRDFFPSVFVKEKHYLTAFYVVECIAMSNSMINTLCFVTVRNNTSKYLKRILRLQWRASPSGSKASADLDLRTTGIPATEEVDCIRLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCW9-1", "uniprot_id": "PKR1_HUMAN", "id": "Q8TCW9-1", "name": "Prokineticin receptor 1", "aln": "METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLDLKTIGMPATEEVDCIRLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:* :.:*:*:* *.*:*. : *.: .:**.***.***** **:***********************************:**.*************************************************:*****************************************:*** ***:********:************: ***************:**:****::**:******::*******:******************:******:*** *:*:*:********************:*************:*******************:*:* **:*:*: *:*:** .*.*:******:* *:************", "identical_positions": 327, "similar_positions": 51, "identity": "83.21%" }, { "cls_id": "homologset.agr.MGI:1929691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BPX9-1", "uniprot_id": "S15A3_MOUSE", "id": "Q8BPX9-1", "name": "Solute carrier family 15 member 3", "aln": "-------------------MSAPRAEEQPSRSGERQPLVARGPRGPRRWRRTAAAA----------------------------VLLVQMLERAAFFGVTSNLVLYLNSLN-------FNWDGQQASRATLLFLGASYLLAPVGGWLADVYLGRFLTISLSLLLYLAASGLLLTTITN--DGRRSFCGEMPELPLEPACPSSSCQGSWSSPYCATTLYLVLLLLALAASSVRSTLTSFGADQVMDLGRDATRRFFNWFYWSINLGAILSLLVVAFIEQNISFLWGYSIIVGLVGLAFFIFLFATPVFITKPPTGSQVSSMLKLAFQNCCP----CRRSSSRDSESAHLLPDQRSNQPGPSPQEDMANFQVLVKILPVMVTLVPYWMVYFQMQSTYVLQGLHLHIPNIFRTNP-NISLLLRSDSSNYRIPEAWLLLANVAVILILIPVKDHLIDPLLLRCKLLPSSLQKMALGMFFGFTSIIVAGVLEKERLQYIAANQTVPQLIGKDLYYAAPLSIWWQIPQYLLIGVSEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGSLLGSGLVALLSFPGG-WMYCPKDFGNINN-CQMDRYFFLLAGIEAVTAVLFLWIAGRYERTRQDPASQRSSSRVRG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924V4-1", "uniprot_id": "S15A3_RAT", "id": "Q924V4-1", "name": "Solute carrier family 15 member 3", "aln": "-------------------MSALRAEQQPSRSGERQPLVAQGRWGPRRWRRTAAAA----------------------------VLLVEMLERAAFFGVTSNLVLYLNSLN-------FNWDGEHASRATLLFLGASYLLAPVGGWLADVYLGRFLAISLSLLLYLAATGLLLTTITD--DGRRSFCGEMPELPLKPACPSANCQGSWSSPYCATTLYLVLLLLALAASSVRSNLTSFGADQVMDLGRDATRRFFNWFYWSINLGAILSLLVVAFIEQNISFLQGYSIIVGLVGLAFFIFLIATPVFITKPPTGSQVSSMLNLAFQNCCPGWQWWRRPSSRNSEGAHLLPDQRSNQPGPSPQEDMANFQVLLKVLPVMVTLVPYWMVYFQMQSTYVLQGLHLHIPNIFRTNP-NISLPLRSDSSNYRIPEAWLLLANVAVILILVPVKDHLIDPLLLRCKLLPSALQKMALGMFFGFTSIIVAGVLEKERLQYIAANQTVPQLIGKDLYYAAPLSIWWQIPQYLLIGISEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGSLLGSGLVALLSLPGG-WMYCPKDFGNINN-CRMDLYFFLLAGIQAVTAVLFLWIAGRYERTRQDPDSQNSTSRVRG----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY34-1", "uniprot_id": "S15A3_HUMAN", "id": "Q8IY34-1", "name": "Solute carrier family 15 member 3", "aln": "-------------------MPAPRAREQPRVPGERQPLLPRGARGPRRWRRAAGAA----------------------------VLLVEMLERAAFFGVTANLVLYLNSTN-------FNWTGEQATRAALVFLGASYLLAPVGGWLADVYLGRYRAVALSLLLYLAASGLLPATAFP--DGRSSFCGEMPASPLGPACPSAGCPRSSPSPYCAPVLYAGLLLLGLAASSVRSNLTSFGADQVMDLGRDATRRFFNWFYWSINLGAVLSLLVVAFIQQNISFLLGYSIPVGCVGLAFFIFLFATPVFITKPPMGSQVSSMLKLALQNCCP--QLWQRHSARDRQCARVLADERSPQPGASPQEDIANFQVLVKILPVMVTLVPYWMVYFQMQSTYVLQGLHLHIPNIFPANPANISVALRAQGSSYTIPEAWLLLANVVVVLILVPLKDRLIDPLLLRCKLLPSALQKMALGMFFGFTSVIVAGVLEMERLHYIHHNETVSQQIGEVLYNAAPLSIWWQIPQYLLIGISEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGSLLGSSLVALLSLPGG-WLHCPKDFGNINN-CRMDLYFFLLAGIQAVTALLFVWIAGRYERASQGPASHSRFSRDRG----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32901-1", "uniprot_id": "PTR2_YEAST", "id": "P32901-1", "name": "Peptide transporter PTR2", "aln": "MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVSDDVANSTERYNLSPSPEDEDFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAPFQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICCGTAIYIAGIFILFITSIPSVGNRDSAIGGFIAAIILIGIATGMIKAN-----------LSVLIADQLPKRKPSIKVLKSGERVIVDSNITLQNVFMFFYFMINVG-SLSLMATTELEYHKGFWAAYLLPFCFFWIAVVTLIFGKKQYIQRPIGDKVIAKSFKVCWILTKN-----------KFDFNAAKPSVHPEKNYPWNDKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFITQASMMELH---------------------GIPNDFLQAFDSIALIIFIPIFEKFVYPFIRRYTPLK-PITKIFFGFMFGSFAMTWAAVLQS---FVYKAGPWYNEPLGHN--TPNHVHVCWQIPAYVLISFSEIFASITGLEYAYSKAPASMKSFIMSIFLLTNAFGSAIGCALSPVTVDPKFTWLFTGLAVACFISGCLFWLCFRKYNDTEEEMNAMDYEEEDEFDLNPISAPKANDIEILEPMESLRSTTKY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. . .: . : . : ...*:. :... : :*:: ** :::*::: : *:: :. .: *: : .* .*: . .**::**.: *:: ::. . :*:*. :* * ..* * * : : . .:. . :*: .. * . ..::*: .. : :..* :**: **:* ***:..: :: : .* .* : . . :*.. :::.. :* :* .. ::. :::. . : .. :. : . :: : ::: : *:: ** * * *::: *. :.: **: :* : .::*::*: :::: *:: * . * .: *: :*::** :: *.**: . : :*. . : : **** *:**..*******.***:***:** **:. **.**: ...** :*..* .: * *:. .. : . * : * . : : ..:: .. . . . ", "identical_positions": 97, "similar_positions": 210, "identity": "14.9%" }, { "cls_id": "homologset.agr.MGI:1929693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TED4-1", "uniprot_id": "G6PT3_HUMAN", "id": "Q8TED4-1", "name": "Glucose-6-phosphate exchanger SLC37A2", "aln": "-----------------------------------------------------------------------------------------MRSSLAPG---------------VWFFRAFS-----------------------RDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYFVVIQVCNG---LVQTTGWPSVVTCVG-----NWFGKGKRGFIMG-IWNSHTSVGNILGSLIAGIWVNGQWGLSFIVPGIITAVMGVITFLFLIE--HPE------DVDCAPPQ-HHGEPAENQDNPEDPGN-------------------SPCSIRESGLETVAKCSK--------GPCEEP----AAISFFGALRIPGVVEFSLCLLFAKLVSYTFL-----------------------------------------YWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAG---------------------------------------------LVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDG--IASSIVMLIICGGLVNG---------------------PYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALG------PLLAGLISPTGWNNVFYMLISADVLAC-----------LLLCRLVYKEILAWKVSLSRGSGYKEI------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WU81-1", "uniprot_id": "G6PT3_MOUSE", "id": "Q9WU81-1", "name": "Glucose-6-phosphate exchanger SLC37A2", "aln": "-----------------------------------------------------------------------------------------MRSSLAPG---------------VWFLRAFS-----------------------RDSWFRGFILLLTFLIYACYHMSRKPISIVKSRLHQNCSEMVRPVNDTHDLNDTTWCSWSPFDKDDYKELLGAVDNAFLVAYAIGMFISGIFGERLPLRYYLSAGMVLSGLFTSLFGLGYFWNIHMLWYFVLIQICNG---LVQTTGWPSVVTCVG-----NWFGKGKRGFIMG-IWNSHTSVGNILGSLIAGVWVNQHWGLSFIVPGIITAIMGVITFLFLIE--YPE------DVDCTPPR-HHDDPEKEQDNPEDPVN-------------------SPYSSRESNVDIAASSSK--------EQGPEP----EAISFLGALRIPGVIEFSLCLLFAKLVSYTFL-----------------------------------------YWLPLYIFNVAHFSAKEAGDLSTLFDVGGIIGGIMAG---------------------------------------------LISDYTNSRATTCCIMLILAAPMMFLYNYIGQNG--ITSSIVMLIICGVLVNG---------------------PYALITTAVSADLGTHESLKGNAKALSTVTAIIDGTGSIGAALG------PLLAGLISPTGWNNVFYMLISADVLAC-----------LLLCRLVYKEILAWKTACGRSSGYKQI------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7SY29-1", "uniprot_id": "G6PT3_DANRE", "id": "Q7SY29-1", "name": "Glucose-6-phosphate exchanger SLC37A2", "aln": "-----------------------------------------------------------------------------------------MKS-LAPG---------------IKLITSFS-----------------------RDSWYRFSILFLTFVFYTSYHLSRKPISIVKSQLHRNCSNVVHPANLNITDNDT-WCDWVPFDGKNYQNLFGVLDNCFLVAYAVGMFFSGIFGERLPLRYYLSTGMLLSGLFTALFGLGFYWQIHSLWYYCLVQALNG---LVQTTGWPAVVACVG-----NWFGKGKRGFIMG-VWNSHTSVGNILGSLIAGVYVSSAWGLSFIVPGIIIASTGVICFLFLVE--RPE------DVNCTAPQ-HHERVE------EEPLL-------------------RNSSTNEEIFNSHTSTAV--------EPVEDHS---EAISFCGALRIPGVVEFSLCLLFAKLVSYTFL-----------------------------------------YWLPLYIANVAHFDPKKAGDLSTLFDVGGILGGIVAG---------------------------------------------LVSDYTGGRASTCCAMLIIAAPMLFLYNKIGQNG--LPTTVGMLLWCGALVNG---------------------PYALITTAVSADLGTHECLRGNSRALSTVTAIIDGTGSIGAAVG------PLLAGLISPTGWNNVFYMLIAADVLAC-----------LLLSRLVYKEIRGWCGYTTRQRGFKEI------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLW5-1", "uniprot_id": "Q8MLW5_DROME", "id": "Q8MLW5-1", "name": "", "aln": "---------------------------------------------------MRTSEQKSSWHYSQPKRIREPSHLDEQHLHLAHCPRRSMRASLGLGRTRKMSNNYNDVPFGIRAVQRLSRQCCTRFH-------------ARRDLLYKMSVFVLTFLAYACYHMCRKPISVVKSVLQGNCSTALAASGQD--------CGYAPFDVPDATTLFGMLDSAFLFSYAIAMFASGFVAERVSLRYFLSMGMILTGVFTYMFGIARTSNIHSLWYFIIVQIFAG---IFQTTGWPGVVALVG-----RWFGKSKRGLIFG-IWNSHTSIGNILGTLIAAHYVESDWALSFVVPGIIIAAVGFLLFLFLVD--QPE------IVGCYPQAGQHERRVANESDVEQDDE-------------------EQVRHNDAEINYRSAPTERTPILPRSQPEAVPRGRGRPISLIDALFIPGVVEFSLCLFFTKLVSYTFM-----------------------------------------YWLPLYIQKSSTLGPELSADLSTLFDVGGILGAIAAG---------------------------------------------YLSDVSGMSATVCTGMLFVASPILLMYQQYGALS--MTISIVLLIVVGIFVNG---------------------PYALITTSVSAELGQHSSLEGNANALATVTAIIDGTGSIGAAVG------PLLAGLISTAGWQYVFHMLIAADIIAM-----------VLLGRLVFKEFAALRRASHRIR--IE-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LFP4-1", "uniprot_id": "A0ABK0LFP4_RAT", "id": "A0ABK0LFP4-1", "name": "", "aln": "MLNFWAPPKHTRRLFQALDLCLFPNNNLTHAPTYFPHLLRLSADILSTKKHSLLFNAHQHPAPPAPASWMKKSMPGGMTPLKKPRNPTKLPLTLNPTKSKDVLAVLAERNQAIVPVGAWVEPASPNWSGIPAHTSAYILEEEIKEQQRRKQESLRHFQRQVKHRVNQQAKLRKKQQLDKSYKAAEKEGSIAIRYSDS--AHLTSKRTSVFPRNLNAAVGSFRLPTSLVLGNATDDAENQNQLFEQQAQALSQTMKQARHQLASFKTVSEKKTSVFLNGGKKSSPTQEDLGCGKISSVVVSEERDNLFESCQQDLLSEDKEKALSKVQKVKFKNPLSVVIKEDEGKQLYPHSLQPVLPEAQGYFVEVKSCLPESQSDVIDVQAVEPKASRIEPKEPGGEPDTQAAGMEFQTTEPDGQAVKTEIQDTLKVQTVELDGDTELEAQDSLPSHQAFLSRDQDFLLNCQYQGSLPKDHCVLPNYQNVLPKYQDQHFLPVAQEFLPTNQLALPKEQNHPLKCQKQDLPPEDQFPLPRHQYILPIYQDRRDPHVLPKCQDHDVLSKAQNYLHSYQEQDLPLQSQSQQPSVRTAERWQEDLYLSGHECLPPRQRRDTCSRRQQLCEEYRSGPSTEQQALLPFQSGVDQEEDKKERQKQYLRHRRIFMDIEREQVKEQNRQREQKRRAEKIKKRKEQERYAEEQRLLRVNCPEEPCSEENISDVLAQLQLQEIKGAREKQQQREKEYVRYVEALRAQVQEKMKLYNITLPPLCCCGPDFWDAHPDTCANNCIFYKNYRAYNRALHSVINSSDISEGNATLRNAIRNFASAHRRNFKTKSPVRG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . :: : . * . ::: ::. *. *. . . . . . :. ..* .. :: : : .*. : . : : . :. : .:: : * : : * . * . ::.:: :: :.: :: . . :. . .: .: . ::. :. ** * . : : . .: : . .:* : . .:.* . *: * **:* . . * ..* .. . : . .: . :: :* . : : : : :: *: ** : .: . . . * : : : : .*: : .* : . : :: : . : . :.:*: . : ", "identical_positions": 29, "similar_positions": 146, "identity": "3.48%" }, { "cls_id": "homologset.agr.MGI:1929699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P37996-1", "uniprot_id": "ARL3_RAT", "id": "P37996-1", "name": "ADP-ribosylation factor-like protein 3", "aln": "MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEETGQELTELLEEEKLSCVPVLVFANKQDLLTAAPAAEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUL7-1", "uniprot_id": "ARL3_MOUSE", "id": "Q9WUL7-1", "name": "ADP-ribosylation factor-like protein 3", "aln": "MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36405-1", "uniprot_id": "ARL3_HUMAN", "id": "P36405-1", "name": "ADP-ribosylation factor-like protein 3", "aln": "MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1MTE5-1", "uniprot_id": "ARL3_DANRE", "id": "Q1MTE5-1", "name": "ADP-ribosylation factor-like protein 3", "aln": "MGLLSILRKLKSTPDQEVRILLLGLDNGGKTTLLKQLASEDITHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRNYFENTDVLIYVIDSADRKRFEETGQELAELLDEEKLSGVPVLVFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKSVNAKRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VD64-1", "uniprot_id": "Q9VD64_DROME", "id": "Q9VD64-1", "name": "ADP-ribosylation factor-like protein 3", "aln": "MGLLSLLRKLRPNPEKEARILLLGLDNAGKTTILKQLASEDITTVTPTAGFNIKSVAADGFKLNVWDIGGQWKIRPYWKNYFANTDVLIYVIDCTDRTRLPEAGSELFEMLMDNRLKQVPVLIFANKQDMPDAMSAAEVAEKMSLVQLQGRTWEIKACTAVDGTGLKEGMDWVCK--NMKK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:****:. *::*.*********.****:*********: :*** ******* ::************ ******:.** ***:******.:**.*: *:*.** *:* :::*. ****:******: * .*:*:** :.* ::.*.*:*::*:*: * *:::**:**** * *: ", "identical_positions": 113, "similar_positions": 47, "identity": "62.09%" }, { "cls_id": "homologset.agr.MGI:1929701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08663-1", "uniprot_id": "MAP2_MOUSE", "id": "O08663-1", "name": "Methionine aminopeptidase 2", "aln": "MAGVEQAASFGGHLNGDLDPDDREEGTSSTAEEAAKKKRRKKKKGKGAVSAVQQELDKESGALVDEVAKQLESQALEEKERDDDDEDGDGDADGATGKKKKKK-KKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQ---DGRTAAWRTTSEEKKALDQ--ASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRK-------LIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILLTAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38062-1", "uniprot_id": "MAP2_RAT", "id": "P38062-1", "name": "Methionine aminopeptidase 2", "aln": "MAGVEEASSFGGHLNRDLDPDDREEGTSSTAEEAAKKKRRKKKKGKGAVSAGQQELDKESGTSVDEVAKQLERQALEEKEKDDDDEDGDGDGDGAAGKKKKKK-KKKRGPRVQTDPPSVPICDLYPNGVFPKGQECEYPPTQ---DGRTAAWRTTSEEKKALDQ--ASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRK-------LIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50579-1", "uniprot_id": "MAP2_HUMAN", "id": "P50579-1", "name": "Methionine aminopeptidase 2", "aln": "MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKK-KKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQ---DGRTAAWRTTSEEKKALDQ--ASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRK-------LIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WVX8-1", "uniprot_id": "A5WVX8_DANRE", "id": "A5WVX8-1", "name": "Methionine aminopeptidase 2", "aln": "---MEANGLPVPPVMDTLIVNGERE-----AEDPAKKKKRKKKKNKSVVSAGHSEQVDDG---ELEVKKPLEQQNLEEKEREEDGEEDGEEADNTSGKKKKKKPKKKKGPKTQTDPPSVPICDLYPSGVFPVGQECEYPPSQ---DGRSAAWRMSDEEKRVLDE--ANEEMWSDFRQAAEAHRQVRRYVKSWIKPGMTMIDICERLEACSRR-------LIKEDGLNAGLAFPTGCSLNNCAAHYTPNAGDPTVLRYDDVCKIDFGTHINGRIIDCAFTVTFNPKFDHLLEAVADATNTGIKCAGIDVRLCDVGESIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMDCSHYMKNFDVGHVPIRLPRAKHLLNVVNENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIIDPYPPLCDTKGSYTAQFEHTILLRPTCKEVVSRGDDY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL89-1", "uniprot_id": "Q9VL89_DROME", "id": "Q9VL89-1", "name": "Methionine aminopeptidase 2", "aln": "-----------MSATETLNVEAATP----EIGEEVKKQKKPKPNNKKLR---------------QEAAAKIASGEGGDEELTTNGDAKPATPAAQPAKKKGNK-GKKSG---QTDPPTIPIAKLYPDGNFPEGEIVEHPTPKDMPDDRTAKDRFTSEEKRALDR--INTDIYQELRQAAEAHRQTRQYMQRYIKPGMTMIQICEELENTARR-------LIGENGLEAGLAFPTGCSLNHCAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKYDKLLQAVKEATNTGIREAGIDVRLCDIGAAIQEVMESYEIELDGKTYPIKAIRNLNGHSISPYRIHAGKTVPIVKGGESTRMEEDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPFVPLRLQSSKQLLGTINKNFGTLAFCKRWLDRAGATKYQMALKDLCDKGIVEAYPPLCDIKGCYTAQYEHTIMLRPTCKEVVSRGDDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38174-1", "uniprot_id": "MAP2_YEAST", "id": "P38174-1", "name": "Methionine aminopeptidase 2", "aln": "-------------------------------MTDAEIENSP--------------------------ASDLKELNLENEGVEQQDQAKADESDPVESKKKKNKKKKKKK------SNVKKIELLFPDGKYPEGAWMDYHQDFN-------LQRTTDEESRYLKRDLERAEHWNDVRKGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGLSLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDATYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKSVPIVKNGDTTKMEEGEHFAIETFGSTGRGYVTAGGEVSHYARSAEDHQVMPTLDSAKNLLKTIDRNFGTLPFCRRYLDRLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFEHTILLHAHKKEVVSKGDDY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. : :: :.: .*** :* ** . * *:*.* :* * :: * :.**.: *.. : :.:.*:.** **:.*: : * ***.:::*.: :* :*: * *: . *:.**** ***:****:****** ***:*:*: *:*:*.::.*.***.***::*: ::* ** ** :** ***: ******* *:* :*********:*::*:** :*. *** ****. ****.**:*****.*::*:***.* :*********:* * . : *** :. : * * :*:** .::.*****.**:*:*** * ** :**::* *::: **** * *.****:****:*:. *****:****", "identical_positions": 183, "similar_positions": 112, "identity": "37.27%" }, { "cls_id": "homologset.agr.MGI:1929704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17028-1", "uniprot_id": "ZNF24_HUMAN", "id": "P17028-1", "name": "Zinc finger protein 24", "aln": "----------------------------------MSAQSVEEDS-ILIIPT---------------PDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWASWELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLNMGVPQIFKYGETCFPKGRFERKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEKLLNVVKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VN1-1", "uniprot_id": "ZNF24_MOUSE", "id": "Q91VN1-1", "name": "Zinc finger protein 24", "aln": "----------------------------------MSAQSVEEDS-ILIIPN---------------PDEEEKILRVKLEEDPDGEEGSSISWNHLPDPEVFRQRFRQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVREHHPENGEEAVAVLEDLESELDDPGQPVSLRRQKREVLVEEITSQEDAQGLPSSELDAVENQLKWASWELHSLRHCDDDATTENGALAPKQEMASAGESHEGPGTLNIGVPQLFKYGETCFPKGRFERKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEKLLNVVKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LTR8-1", "uniprot_id": "A0ABK0LTR8_RAT", "id": "A0ABK0LTR8-1", "name": "", "aln": "MATPGFGFPIPSRPPPRPADRKPCAPGACGKRLKAAAQRLPGTTRLWRVPSQRSAARGGRVRGGGGSDEEEKILRVKLEEDPDGEEGSSISWNHLPDPEIFRQRFRQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPRELQTLVREHHPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEEIASQEDAQGLPSSELDAVENQLKWASWELHSLRHCDDDATAENGALAPKQEIASAGESHEVPGTLNIGVPQIFKYGETCFPKGRFERKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEKLLNVVKV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** : : : :*. .***********************.********:*******************************************************:**** **:**********:********************:*******::.***:********************************. :**********:.** **** *****:****:**********************************************************************************************************************************************", "identical_positions": 334, "similar_positions": 23, "identity": "79.9%" }, { "cls_id": "homologset.agr.MGI:1929705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWA3-1", "uniprot_id": "A0A0G2JWA3_RAT", "id": "A0A0G2JWA3-1", "name": "", "aln": "MADHVQSLAQLENLCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQKDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEIN---QADTTHPLTKHRKIASSFRDSSLFDIFTLSCNLLKQAS--GKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPSFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRLLARLKSNYQLGELVKVENYPDVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASVPYVKATEPHMLETYTPEVTKAYITSRLESVHIILSRDGLEDPLEDTGLVQQQLDQLSTIGRCEYEKTCALLVQLFDQSAQSYQELLQSASASPMDIAVQEGRLTWLVYIIGAVIGGRVSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYRRLSEVLGLNDETMVLSVFIGKVITNLKYWGRCEPITSKTLQLLNDLSIGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTALGRLLMVDLGEDEDQYEQFMLPLTAAFEAV-AQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFEWIYPS-YMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILLFRETSKMITMYGNRILTLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFGVFRLYGDDALENALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPHVIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRST----KKRTAPLNRESDCFLHIMQQHPAMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFSDLRNSIVNSQPPEKQQAMHLCFENLMEGIERNLLTKNRDRFTQNLSAFRREVNDSMKNSTYGVNSNDMMS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPK7-1", "uniprot_id": "XPO7_MOUSE", "id": "Q9EPK7-1", "name": "Exportin-7", "aln": "MADHVQSLAQLENLCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQKDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEIN---QADTTHPLTKHRKIASSFRDSSLFDIFTLSCNLLKQAS--GKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPSFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRLLARLKSNYQLGELVKVENYPDVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASVPYVKATEPHMLETYTPEVTKAYITSRLESVHIIL-RDGLEDPLEDTGLVQQQLDQLSTIGRCEYEKTCALLVQLFDQSAQSYQELLQSASASPMDIAVQEGRLTWLVYIIGAVIGGRVSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYRRLSEVLGLNDETMVLSVFIGKVITNLKYWGRCEPITSKTLQLLNDLSIGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTALGRLLMVDLGEDEDQYEQFMLPLTAAFEAV-AQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFEWIYPS-YMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILLFRETSKMITMYGNRILTLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFGVFRLYGDDALENALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPHVIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRST----KKRTTPLNRESDCFLHIMQQHPAMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFSDLRNSIVNSQPPEKQQAMHLCFENLMEGIERNLLTKNRDRFTQNLSAFRREVNDSMKNSTYGVNSNDMMS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIA9-1", "uniprot_id": "XPO7_HUMAN", "id": "Q9UIA9-1", "name": "Exportin-7", "aln": "MADHVQSLAQLENLCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQKDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEIN---QADTTHPLTKHRKIASSFRDSSLFDIFTLSCNLLKQAS--GKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPSFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRLLARLKSNYQLGELVKVENYPEVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASVPYVKATEPHMLETYTPEVTKAYITSRLESVHIIL-RDGLEDPLEDTGLVQQQLDQLSTIGRCEYEKTCALLVQLFDQSAQSYQELLQSASASPMDIAVQEGRLTWLVYIIGAVIGGRVSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYRRLSEVLGLNDETMVLSVFIGKIITNLKYWGRCEPITSKTLQLLNDLSIGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTALGRLLMVDLGEDEDQYEQFMLPLTAAFEAV-AQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFEWIYPS-YMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILLFRETSKMITMYGNRILTLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFGVFRLYGDDALDNALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPHVIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRST----KKRTTPLNQESDRFLHIMQQHPEMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFSDLRNSIVNSQPPEKQQAMHLCFENLMEGIERNLLTKNRDRFTQNLSAFRREVNDSMKNSTYGVNSNDMMS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B208-1", "uniprot_id": "A0A8M2B208_DANRE", "id": "A0A8M2B208-1", "name": "", "aln": "MADHVQSLAQLEILCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLSKLVSRTSNPLPLEQRIDIRNYVLNYLATRPKLAAFVTQALIQLYARITKLGWFDCQKEDYVFRNVIVDVTRFLQDSVEHCIIGVTILSQLTNEINQVLQADSTHPLTKHRKIASSFRDSSLFDIFTLSCNLLKQAS--GKNLNLNDESQHGLLMQLLKLAHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPSLSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRLLARLKSNYQLGELVKVENYPEVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASVPYVKATEPHMLETYTPEVTKAYITSRLESVHIIL-RDGLEDPLDDAGLVQQQLDQLSTIGRCEYEKTCALLVQLFDQSAQSYQELLQSTNSSTMDIAVQEGRLTWLVYIIGAVIGGRVSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYRRLSEVLGLNDETMVLSVFIGKIITNLKYWGQCEPITSKTLQLLNDLSIGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGVNNQANLSDMRCRTTFYTALGRLLMVDLGEDEDQFEQFMLPLTAAFEAV-AQMFSTNTFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFDWIYPS-YMPILQRAIELWYHVPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILLFRETSKMITTYGNRILTLGEVPKDQVYALKLKGISICFSMLKAVLSGNYVNFGVFRLYGDDALDNALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPHVVMYILSSISEGLTALDTMVCTGCCSSLDHIVTYLFKQLSRST----KKRVAPMAQESDRFLHIMQQHPEMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFADLRNSIVNSQPPEKQQAMHLCFENLMEGIERNLLTKNRDRFTQNLSVFRREVNDSMKNSTYGVNSNDMMS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GQN0-1", "uniprot_id": "RBP16_DROME", "id": "Q9GQN0-1", "name": "Ran-binding protein 16", "aln": "-----MDIQQLEVLCKQLYEATDIRIRSEAEKALVTFVSSQDALPKCQLLLQRADSSYAQLLAASTLTKLIQG----LSLQERIDIRSYALNYLATVPNLQHFVVQALVSLLAKLTKYGWFDSYKEEMVFQNLLEDVKKFLQGSVEHCTIGVQILSQLVCEMNSVVEMDVQVSFSKMRKIATSFRDQQLLETFLLSCSLLVSARDNSKNISFMDESQQALISHVLRLTKNCLSFDFIGSSTDESADDMNNVQIPTAWRPAFLDSNTLKLFFDLYQILPNGLASYSISCLVQITSVRRSLFNNSERTKFLTHLVEGVKDILTTLHGLSDPDNYHEFCRLLARLKSNYQLGELIAVPCYPEAIQLIAKFTVESLHLWLFAPNSVHYLLTLWQRMVASVPYVKSPDPHLLGTYTPEVIKAYIESRLDAVPVII-RDNLDDPLDDFCMVQQQLEQLSVIERCEYNKTCNLLVQHFDQKAREYENLLQTPNANSIDITIHELQLTWLVYIIGSAIVGRLTVATSDEHDTMDAELVIRVLQLMTLTDARLPQAGCEKLELAILSFLDQVRKMHSSEQAQKAN-LNKRLSEVFGLTDEQMLLSFINRKIITNLKFWGRSESIITKTLMLLSELSVHFNSVRKLARLEEVQFMLTHHTSEHFPFLGTN--SSLSEMRCRTMFYTSLGRLLMFDLGEDEERFYNFLEPLTNQFESLGSVMMDNNIFSNEEAKKVIIGLARDLRGLALPLNARIQYTMLFEWLYYADYLPILLRAMDLWAHDPAVTTPILKLFAELVHCRTQRLAGNVSSPMGILLFREASKLICIYGNRILHQ-EVPRERLYPMRLKGIAICFLILKNSLGGNYVNCGVFKLYGDDTLDSVLNIIAKLILTIEQRDLIEYPKLSTAYYNLLNCLSQDHVSYLAALEPAAFVYILKSLTKGLAALDSATYISCCTILDSIVSYIFKQLQMKVSTFPNKKLRSLNQENVQFLKVVEMNSELLQSMMSSLLNNVLQEDCRNQWSMSRPLLVLILLYEDYYRSLKDRIICAQPIEKQQTMAQWFDDLMVGIERNVSSKNKEKFTQNMSTFRRDVVN-LPKSTAAFSCDRPMCDGGFEPSEPESSPH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *** *******:** * :****** *..* *.*.******:*..***:*****: *:**:. *.*::*****.*.****** *:* **.***:.* *::** ****. *:: **:* : **.:***.***:* *** *****. *:* : * .::* ****:****..*:: * ***.** .* .**:.: ****:.*: ::*:*::***.*****:*****:**: .*****:**.*****.**:******: :* .::. :******:*********:**:***:***:*** ** . :.****:*********************: * **:.*:***:*** **: * **********:****:.*******:.:**:* ****** **** ***::* :*: **.*:***:* :*****:***.* ****:*** **** ***.*:.*::***:..:..:**:::* :*********:.* **::.*::**:*:**.*** ******.***:**.*** ******:***::*.**:: .:*.**:. * :*****:**.** *:**.: *:*****:**:.*.* :*** **.:**: :.*****.:*. *****.:******.*** * :.*::***** ***:******.******::: :*: *** **:: : *:..* *.::***:.::**.*****:*:.:**: .: ***:*:* : *:*** **::** * ** ***:***:***** *:*** :**** *******:**:* ****** ***::::*.::****:*** :** *.*.*** ***:*****:*:..*: : **:*:* : **::***** :**.**: *:***:.::*:*** ..:***.*:::**:***: . .**: ** **:*:****. .. :*: .: :*. **:::: :. ::*.*:*::** :: ************** **** *.*: .*:: *: :** ****:* *::** *****: :**:::****:*.***:* : : :** ....: *. ", "identical_positions": 625, "similar_positions": 313, "identity": "56.15%" }, { "cls_id": "homologset.agr.MGI:1929706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L397-1", "uniprot_id": "A0ABK0L397_RAT", "id": "A0ABK0L397-1", "name": "", "aln": "MVELVTGYRRSTERGQSIPVRRGASTCYLVPTDVHKPLSKLAALYSQGPGTLAGIAGTVDIQSLAELEALCTHLYVGTDLNERIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVTRINPLPVEQRIDIRNYILNYVASQPKLAPFVIQALIQVIAKLTKLGWFEVQKDEFVFREIIADVKKFLQGTVEHCIIGVIILSELTQEMN---LVDYSRPSAKHRKVATSFRDTSLKDILVLACSLLKQVL--AKPLNLQDQDQQSLVMQVLKLVLSCLSFDFLGSSADESADDLCTVQIPTTWRTIFLEPETLDLFFNSYHSLPPLLSQLALSCLVQFASTRRSLFSSPERAKYLGNLIKGVKRILENPQGLSDPGNYHEFCRFLARLKTNYQLGELVLVKEYAEVIGLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPFVKSAEPHLLDTYAPEITKAFITSRLESVAIVVRDNLEDPLDDTATVFQQLEQLCTVSRCEYEKTCTLLVQLFDQNAQNYQKLLHSASGLAIDMAIQEGRLAWLIYLVGTVVGGRLTYTSTDEHDAMDGELSCRVFQLISLMDTRLPRRTNEKIELAVLWFLDQFRKTYVGDQLQRTSKVVRPKNDVSRVPEKAWKIVKVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRCEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTREHFPFLGISDTYSVSDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVSFETVLQIFNNN--FKQEEVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMYPA-YLPVLQRAIERWYGEPACTTPILKLLAELMQNRSQRLNFDVSSPNGILLFREASKMICTYGNQILSLGSLSKDQIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFITNLEPPVLLYVLTSLSEGLTTLDTVVSSSCCTSLDYMVTYLFKHIAKEGKKP--LRCREAMQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLAQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRS-----------DGHTELCSLDMMS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NF8-1", "uniprot_id": "RBP17_MOUSE", "id": "Q99NF8-1", "name": "Ran-binding protein 17", "aln": "--------------------------------------------------------MALHFQSLAELEVLCTHLYVGTDLTERIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVTRINPLPIEQRIDIRNYILNYVASQPKLAPFVIQALIQVIAKLTKLGWFEVQKDEFVFREIIADVKKFLQGTVEHCIIGVIILCELTQEMN---LVDYSRPSAKHRKIATSFRDTSLKDILVLACSLLKQVL--AKPLNLQDQDQQSLVMQVLKLVLSCLNFDFLGSSADESADDLCTVQIPTTWRTIFLEPETLDLFFNLYHSLPPLLSQLALSCLVQFASTRRSLFSSPERAKYLGNLIKGVKRILENPQGLSDPGNYHEFCRFLARLKTNYQLGELVLVKEYAEVIGLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPFVKSAEPHLLDTYAPEITKAFITSRLESVAIVVRDNLEDPLDDTATVFQQLEQLCTVSRCEYEKTCTLLVQLFDQNAQNYQKLLHAAPGLAVDMAIQEGRLAWLIYLVGTVVGGRLTYTSTDEHDAMDGELSCRVFQLISLMDTRLPHCTNEKIELAVLWFLDQFRKTYVGDQLQRTS--------------------KVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRCEPVISRTLQFLSDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISETYNVGDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVSFETVLQIFNNN--FKQEEVKRMLIGLARDLRGIAFALNTKTSYTMLFDWIYPA-YLPVLQRAIERWYGEPACTTPILKLLAELMQNRSQRLNFDVSSPNGILLFREASKMICTYGNQILSLGSLSKDKIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFITNLEPPVLLYVLTSLSEGLTTLDTVVSSSCCTSLDYMVTYLFKHIAKEGKKP--LRSREAMQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLGQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRS-----------DGHTDLSSLDMMS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2T7-1", "uniprot_id": "RBP17_HUMAN", "id": "Q9H2T7-1", "name": "Ran-binding protein 17", "aln": "--------------------------------------------------------MALHFQSLAELEVLCTHLYIGTDLTQRIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVSRVSPLPVEQRMDIRNYILNYVASQPKLAPFVIQALIQVIAKITKLGWFEVQKDQFVFREIIADVKKFLQGTVEHCIIGVIILSELTQEMN---LVDYSRPSAKHRKIATSFRDTSLKDVLVLACSLLKEVF--AKPLNLQDQCQQNLVMQVLKLVLNCLNFDFIGSSADESADDLCTVQIPTTWRTIFLEPETLDLFFNLYHSLPPLLSQLALSCLVQFASTRRSLFNSPERAKYLGNLIKGVKRILENPQGLSDPGNYHEFCRFLARLKTNYQLGELVMVKEYPEVIRLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPFVKSTEPHLLDTYAPEITKAFITSRLDSVAIVVRDHLDDPLDDTATVFQQLEQLCTVSRCEYEKTCALLVQLFDQNAQNYQKLLHPYSGVTVDITIQEGRLAWLVYLVGTVVGGRLTYTSTDEHDAMDGELSCRVFQLISLMDTGLPRCCNEKIELAILWFLDQFRKTYVGDQLQRTS--------------------KVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRYEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDNHSLSDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVAFETVLQIFNNN--FKQEDVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMYPT-YLPLLQNAVERWYGEPTCTTPILKLMAELMQNRSQRLNFDVSSPNGILLFREASKMVCTYGNQILSLGSLSKDQIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTLDTVVSSSCCTSLDYIVTYLFKHIAKEGKKP--LRCREATQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLAQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRS-----------DGNTEPCSLDMMS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9GQN0-1", "uniprot_id": "RBP16_DROME", "id": "Q9GQN0-1", "name": "Ran-binding protein 16", "aln": "-------------------------------------------------------------MDIQQLEVLCKQLYEATDIRIRSEAEKALVTFVSSQDALPKCQLLLQRADSSYAQLLAASTLTKLIQGLS---LQERIDIRSYALNYLATVPNLQHFVVQALVSLLAKLTKYGWFDSYKEEMVFQNLLEDVKKFLQGSVEHCTIGVQILSQLVCEMNSVVEMDVQVSFSKMRKIATSFRDQQLLETFLLSCSLLVSARDNSKNISFMDESQQALISHVLRLTKNCLSFDFIGSSTDESADDMNNVQIPTAWRPAFLDSNTLKLFFDLYQILPNGLASYSISCLVQITSVRRSLFNNSERTKFLTHLVEGVKDILTTLHGLSDPDNYHEFCRLLARLKSNYQLGELIAVPCYPEAIQLIAKFTVESLHLWLFAPNSVHYLLTLWQRMVASVPYVKSPDPHLLGTYTPEVIKAYIESRLDAVPVIIRDNLDDPLDDFCMVQQQLEQLSVIERCEYNKTCNLLVQHFDQKAREYENLLQTPNANSIDITIHELQLTWLVYIIGSAIVGRLTVATSDEHDTMDAELVIRVLQLMTLTDARLPQAGCEKLELAILSFLDQVRKMHSSEQAQKAN---------------------LNKRLSEVFGLTDEQMLLSFINRKIITNLKFWGRSESIITKTLMLLSELSVHFNSVRKLARLEEVQFMLTHHTSEHFPFLGTNS--SLSEMRCRTMFYTSLGRLLMFDLGEDEERFYNFLEPLTNQFESLGSVMMDNNIFSNEEAKKVIIGLARDLRGLALPLNARIQYTMLFEWLYYADYLPILLRAMDLWAHDPAVTTPILKLFAELVHCRTQRLAGNVSSPMGILLFREASKLICIYGNRILHQ-EVPRERLYPMRLKGIAICFLILKNSLGGNYVNCGVFKLYGDDTLDSVLNIIAKLILTIEQRDLIEYPKLSTAYYNLLNCLSQDHVSYLAALEPAAFVYILKSLTKGLAALDSATYISCCTILDSIVSYIFKQLQMKVSTFPNKKLRSLNQENVQFLKVVEMNSELLQSMMSSLLNNVLQEDCRNQWSMSRPLLVLILLYEDYYRSLKDRIICAQPIEKQQTMAQWFDDLMVGIERNVSSKNKEKFTQNMSTFRRDVVNLPKSTAAFSCDRPMCDGGFEPSEPESSPH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :**.**.:** .**: * ******: ::.* :.*.******::. :********: *:**: :. :::*:***.* ***:*: *:* **:***:.::**:** ***: *:::**:::: ********:**** *** **.:*. *** :* . . :* **:****** .* : ::*:**** .. :* :.: *: ** *: :**:*. .**.***:***:******: .*****:**. **:.:**.***: *: ** *:. ::*****::*.*****...**:*:* :*::*** ** . :*****.*******:*****:*******: * *.*.* ***:**: **: * *********************:***.:****.**:**: **:* ***::*.:::**:*:***** . * ******..:.****:*** **** ***:*::*::**:. . ::*::*:* :*:**:*::*:.: **** :::****:**.** **:**::* *: **: **:***:* ****.** : .:* *::. : *:***:*:**:: :*. : **:****:*** *.:*::** :*.:*** : ::**.::: *:***.:** ******* .. .:.::**** ***:* ****.******:.* **: *** **:: .:: :* *.:*:.*:::*********:*:.**:: .*****:*:* : ***:* .*:: * :*: *******:***:: *:*** :**** **********::* ***:** .:.::::***:****:**: **.:* ****. ********: :*.**: :.*::*::.: **::* *** :** **:**:***:*:: ***..::*:*.*:::**::**:.. **** ** :*:*:**:: : .. : *. * . ::*:.:: *.::**.*** *:*.:: ********:***** **** *.*: .*: :* :**: **:.:.* * :** *:*:*:* **:::****:*.*****.: :* ** : .. : . ", "identical_positions": 562, "similar_positions": 349, "identity": "47.39%" }, { "cls_id": "homologset.agr.MGI:1929709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7S5-1", "uniprot_id": "M0R7S5_RAT", "id": "M0R7S5-1", "name": "Perilipin-4", "aln": "MSASGDGTRGSPKSKGKTLRSFFGSLPGFSSAWNPVSHTKCST--KDVQTAVDPSGTPVPPSPVATNPQMARDASGLLQLSEQTAGDKNMGSIGATSSQDAFYSGVAGIMDAAKGKVQGSLSATQLALVGTKETVSGGVMGAVDMAKGLVKGGLDTSKSVLMGTKDTVTTGLTGAVNMAKGTVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGTVQTGLDTSKSVLMGTKDTVTTGLTGAVNMAKGTVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGSVQTGLDTSKSVLMGTKDMVTTGLTGAVNLAKGSVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGSVQTGLDTSKSVLMGTKDTVATGLTGAVNMAKGTVQTGLDTSKSVLMGTKDMVTTGLTGAVNLAKGSVQTGLDTSKSVLMGTKDTVTTGLTGAVNMAKGTVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGSVQTGLDTSKSVLMGTKDMVTTGLTGAVNLAKGSVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGSVQTGLDTSKSVLMGTKDTVATGLTGAVNMAKGTVQTGLDTSKSVLMGTKDMVTTGLTGAVNLAKGSVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGSVQTGLDTSKSVLMGTKDTVATGLTGAVNMAKGTVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGTVQMGLDTSKSVLMGTKDTVTTGLTGAVNMAKGTVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGTVQTGLDTSKSVLMGTKDTVATGLTGAVNMAKGTVQMGLDTSKSVLMGTKDTVTTGLTGAVNLAKGSVQTGLDTSKSVLMGTKDTVATGLTGTMNLAKGTVQMGLDTSKSVLMGTKDTVTTGLTGAVNMAKGTVQMGLDTSKSVLMGTKDTVTTGLTGTMNLAKGTVQMGLDTSKSVLMGTKDTVATGLTGTMNLAKGTVQTGLDTSKSVLMGTKDTVATGLTGAVNMAKGTVQMGLDTSKSVLMGTKDTVATGLTGAVNMAKGTVQTGLDTSKSVLMGTKDTVTTGLTGTMNLAKGTVQTGLDTSKSVLMGTKDTVTTGLTGAVNVVKGVAQGGLDTSKSVLMGPKNTVCAGAPGAINVVKGAAQGGLDTSNSAFPGTKSAMLAGFAGAMDMARGTAQTGLHPSKHILTGTEDMVCAGVTSIMDTAKDSQKNMDTTRDRLSTMLAHSAIRSMEECGHPAATH-------FATLPDELKGLGDFFQPMTAEEQAQLAASESGSRVLSANRGSYYICLGDLAPSFRQRAFEHALSHIQHNQFQARAALAQLQEAFQMIPTEFGKDR-----DIVGCKVADSWGKSMMRASVAQDRLCALVHQLHAAYSSLATSLQGLP-EVQQQAGQARHSLCKLYGLVTSEAG-SELQTEQLAQSSAGVVQAWQGLEVLLDKLQQNPPLDWLVGPFTLMPCGQLQAPEGWVGGVPRDHAMTTDDCTSPKLWIEQDQRVLRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88492-1", "uniprot_id": "PLIN4_MOUSE", "id": "O88492-1", "name": "Perilipin-4", "aln": "MSASGDGTRVPPKSKGKTLSSFFGSLPGFSSARNLVSHTHSSTSTKDLQTATDPSGTPAPSSKVSTNSQMAGDAAGLLQPSEQTAGDKDMGSFSVTSSEDAFS-GVFGIMDAAKGMVQGGLGATQSALVGTKEAVSGGVMGAVGVAKGLVKGGLDTSKNVLTNTKDTVTTGVMGAANMAKGTVQTGLDTTKSVVMGTKDTVATGLAGAVNVAKGTIQGGLDTTKSVVMGTKDTVTTGLTGAVNVAKGVVQGGLDTTKSVVMGTKDTVTTGLTGAMNVAKGTAQMGIDTSKTVLTGTKDTVCAGATGAINVAKGAAQGGLDTTKSVLIGTKDTVTTGLTGAVNVAKGAVQGGLDTTKSVVMGTKDTVTTGLTGAMNVAKGTAQMGLGTSKTVLTGTKDTVCAGLTGAINVAKGAAQGGLDTTKSVLMGTKDTVTTGLTGAVNVAKGTIQGGLDTTKSVVMGTKDTVTTGLTGAVNVAKGTIQGGLDTTKSVVMGTKDTVTTGLTGAVNVAKGAAQGGLDTTKSVVMGTKDTVTTGLTGAMNVAKGTAQMGLGTSKTVLTGTKDTVCAGLTGAINVAKGAAQGGLDTTKSVLMGTKDTVTTGLTGAVNVAKGTIQGGLDTTKSVVMGTKDTVTTGLTGAVNVAKGAVQGGLDTTKSVVMGTKDTVTTGLTGALNVAKGTAQMGIDTSKTVLIGTKDTVCAGATGAINMAKGAAQGGLDTTKSVLMGTKDTVTTGLTGAINVAKGSAQGGLDTTKSVLIGTKDTVTTGLTGALNVAKGTVQTGLDTSQRVLTGTKDNVYAGVTGAVNVAKGTIQGGLDTTKSVVMGTKDTVTTGLTGAVNVAKGAVQGGLDTTKSVVMGTKDTVTTGLTGAMNVAKGTAQMGIDTSKTVLTGTKDTVCAGLTGAINVAKGATQGGLDTTKSVLMGTKDTVTTGLTGAINVAKGAAQGGLDTTKSVLLGTKDTVTTGLTGAANVAKETVQMGLDTSKNILMDTKDSICAGATGAITVVKGAAQGGLDTSN-----------AALTGTMDTAKGTVQTSLDTSKHMLIGMKDTVCAGVTSAMNMAKG-IHKNTDT-------TRDTQSSVLAHSGNVATNAIHTGVHTVPSSLSGSHSIICHEPSIYRATNHGVGQAILTSTESLCCETSS-----FSDKYGLGHVTEPR--ADTKTLVSGMASSACA------------------------------ATRSVEECGQLAATG-------FAALPDELKGLGDIFQPMTTEEQAQLAVSESGPRVLSADRGSYYIRLGDLAPSFRQRAFEHALSHIQHNQFQARAALAQLQEAFQMTDMTMEAACGKLCSDQSLNTMVEAVGSHEMRASVAQDRLCTLAHQLHAAYSSLVTSLQGLP-EVQQQAGQARHSLCKLYGLVSSEAG-SELQTEQLAQSSAGVVEAWQGLEVLLEKLQQNPPLSWLVGPFTSMPCGQL-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96Q06-1", "uniprot_id": "PLIN4_HUMAN", "id": "Q96Q06-1", "name": "Perilipin-4", "aln": "MSAPDEGRRDPPKPKGKTLGSFFGSLPGFSSARNLVANAHSSAR---ARPAADPTGAPA--------AEAAQPQAQVAAHPEQTAPWTEK------------------ELQPSEKMVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVSSGVTGAMDMAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTKTVLTGTKDTVTTGVMGAVNLAKGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVARGSIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDTTKSMVMGTKDTMSTGLTGAANVAKGAMQTGLNTTQNIATGTKDTVCSGVTGAMNLARGTIQTGVDTTKIVLTGTKDTVCSGVTGAANVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNVAKGTVQTGVDTTKTVLTGTKDTVCSGVTSAVNVAKGAVQGGLDTTKSVVIGTKDTMSTGLTGAANVAKGAVQTGVDTAKTVLTGTKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTGTKDTIYSGVTSAVNVAKGAVQTGLKTTQNIATGTKNTFGSGVTSAVNVAKGAAQTGVDTAKTVLTGTKDTVTTGLMGAVNVAKGTVQTSVDTTKTVLTGTKDTVCSGVTGAANVAKGAIQGGLDTTKSVLTGTKDAVSTGLTGAVKLAKGTVQTGMDTTKTVLTGTKDAVCSGVTGAANVAKGAVQMGVDTAKTVLTGTKDTVCSGVTGAANVAKGAVQTGLKTTQNIATGTKNTLGSGVTGAAKVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNLAKGTVQTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGTVQTGVDTAKTVLSGAKDAVTTGVTGAVNVAK---------------------------------GTVQTGVDASKAVLMGTKDTVFSGVTGAMSMAKGAVQGGLDTTKTVLTGTKDAVSAGLMGSGNVATGATHTGLSTFQNWLPSTPATSWGGLTSSRTTDNGGEQTALSPQEAPFSGISTP-----PDVLSVGPEPAWEAAATTKGLATDVATFTQG------------------------------AAPGREDTGLLATTHGPEEAPRLAMLQNELEGLGDIFHPMNAEEQAQLAASQPGPKVLSAEQGSYFVRLGDLGPSFRQRAFEHAVSHLQHGQFQARDTLAQLQDCFRLIEKAQQAPEGQPRLDQGSGASAEDAAVQEERDAGVLSRVCGLLRQLHTAYSGLVSSLQGLPAELQQPVGRARHSLCELYGIVASAGSVEELPAERLVQSREGVHQAWQGLEQLLEGLQHNPPLSWLVGPFALPAGGQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***..:* * .**.***** ************ * *::::.*: :.*.**:*:*. .: * : : .**** .: ::.:: *.*. . . : :*::**.** ..*.:***:*:*****::..* .**:.*::*: ** :****:** ****:*:*: ******:***:*::*:****:* *:**:*:*: *********: ****:***.** *::*:*:*: ****:*:*****::*:*:*: * *:****:** **** * :* ***:*:***: * *:**:*:** ****** :*:**::*:***::* *:**:*:*: ****** :*:***:*:**** * *:.*:*:** ***: * :*:***:*:** : * ****:**::******::******.*:***::* **:*::.: ****** :*:**::*:*:*::* *:**:* *: **** * :*:***.*:***:.* ****:***: ****:*:*****::*:***:.* *:.*:*:** ******.:*:*.*:*:***:.* ****:***::**** ::******.*:***::* *:**:*:*: **********.*::*:***:** *:**:*:*: *****: :*:*.*:*:***:.* *:.*::.: ***:*. :* *.::*:***:.* *:**:*:** ********** **:*:***:.* .:**:*:** ****** :*:**: *:***::* ****:: ** **** * :*:****::****:* *:**:*:*: ****:* :*:***.*:***:** *:**:*:*: ****** :*:**: *:***:.* *:.*::.: ***:*: :*:*** ::***:.* ****:**** ****:*:*****::*:***:.* *:**:*:** ****** :*:**: *:** *** *:**:*.:* .:**:: :* ***:.:.* *****.:*:** :*:* **** :*:*.:*.:*** :: . ** *:*: :: * : **.... : *: * . * .. . . :* * * . :: .: .. .:. . :* : :. . . * . *: * *:* :* * :**:****:*:**.:*******.*:.*.:****::***:: ****.***********:**:**.***** :*****:.*:: * .: . * : . .*:* * :***:***.*.:****** *:** .*:******:***:*:* .. .** :*:*.** ** :****** **: **:****.******: . ** ", "identical_positions": 714, "similar_positions": 407, "identity": "47.41%" }, { "cls_id": "homologset.agr.MGI:1929711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIT4-1", "uniprot_id": "D3ZIT4_RAT", "id": "D3ZIT4-1", "name": "Anaphase-promoting complex subunit 7", "aln": "MMGQPLSPHDCLFLRRHIRSNLYLRGAEPRLDQKDPAAAAILELSLRLGSAPGGSVSCCWVTVSPGRMSVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRP-STGNSASTPQSQCLPSEIEVKYKMAECYTMLKLDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQE-----RPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREG----RLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAT--VCLEDPVTQEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEGS---------------------------PTDATQEDDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVM3-1", "uniprot_id": "APC7_MOUSE", "id": "Q9WVM3-1", "name": "Anaphase-promoting complex subunit 7", "aln": "-------------------------------------------------------------------MSVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYAMALQQKKALSKTSKVRP-STGNSASTPQSQCLPSEIEVKYKMAECYTMLKLDKDAIAVLDGIPSRQRTPKINMMLANLYKKAGQE-----RPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDSKNSVLKFEQAQMLDPYLIRGMDVYGYLLAREG----RLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAT--VCLEDPVTQEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEES---------------------------PTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX3-1", "uniprot_id": "APC7_HUMAN", "id": "Q9UJX3-1", "name": "Anaphase-promoting complex subunit 7", "aln": "-------------------------------------------------------------------MNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRP-STGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQE-----RPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREG----RLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAT--VCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEES---------------------------PTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9C3Q3-1", "uniprot_id": "A9C3Q3_DANRE", "id": "A9C3Q3-1", "name": "", "aln": "-------------------------------------------------------------------MNVIDHVRDMAAAGLHSNVRIISSLLLTMSTNNPELFSPSQKYQLLVYHADAIFHDKEYRNAACKYNMALQQKKMLSKTSKVRPSSTGSTTSAVQAQNLPSEIEVKYKIAECYTILKLDKDAISVLDGIPSRQRTPKINMMLANLYRKAGQE-----RSAVTSYKEVLRQCPLALDAIIGLLSLSVKGAEVASMTMDVIQSIPNLDWLSVWIKAHAFIHGGDNQRAINTICSLEKKSLLRDNVDLLVTLADVYFRAGDTKNSILKFEQAQMLDPYLIKGMDVYGYLMAREG----HLEDVEVLGGRLFNISDQHAEPWVISGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGVALRNMGRVQEAIIHFREAMRLAPCRLDCYEGLIDCYLASNGIREAMGMANNIYKTLGANAQTLTILAT--VCLEDPMTQEKAKTLLDKALAQRPDYIKAVVKKAELLSREQKYEEGIALLRNTLANQSDCVLHRMLGDFLVAVNDYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEES---------------------------PTDATVELDGDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3Y6-1", "uniprot_id": "Q9W3Y6_DROME", "id": "Q9W3Y6-1", "name": "", "aln": "-------------------------------------------------------MASFLIVVEKMEIALFANAKKLYDHKLYECVIPAADLLRTVLKNDRYVATLDVEYQVLLYLLNANYKERNYRAALRHFDEIIHKRRLMMRHKNAVLVAIESSYPEFG------DAEQRRRAAECYRQIGNTDMAIETLLQVPPTLRSPRINLMLARLQHHGSRHGTTKKSEAVLAYKEVIRECPMALQVIEALLELGVNGNEINSLVMHAATVPDHFDWLSKWIKALAQMFNFKHSDASQTFLMLHDNTTLRCNEHLMMALGKCLYYNGDYFQAEDIFSSTLCANPDNVEAIGLMAVLCGQEGGCEQDSADMDYLFAKVSSEVKYTASHWFAHAQLLYDEGKFERGLNFVEKCLDSEPRNHEALILRGRLLIALERHTQAVCAFRTAQMVAPYRFEIYRGLFHSYLAQKRFKEANALCNWTIRLFQNSPRSFTMFGRTLFLFPDPRMRRTARKFAEKSLKINHIYTPAVNLIADICQVEGPTKAIIKLLEKHVIIFPKVNLLNHLGDIMRKQKEPVKAMEYYYKALRQDPKSKRTLRGLRLLAKSDDESPVLDESDDIGMDNQQSINDLTTLCEATNAQGAEGAESVENSREASSSAAARSGQEEDVDEHDWIDVPDGMSY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :.:.: *:. * :.** *: .*: : : :**:*:* :: :::::** * :: ::::: : : .:. : .: . : * : : **** : . ** * :*. *:*:**:***.* ::..:. :* :****:*:**:**:.* .**.*.*:* *: *:.*.. ::**** **** * :. .:. * .*: *..:: ** * .*: :*.. : ** :: *..: :* :..:.: . * .:** *:: * :: . . *. *. . : . ::.*.* : *.:: :... :**:*:* * : * :*: ** * :** *:: *.**:..***.: ::** :.* : : ..:::*::. . : ** :..*:.: :*:* . * ** *:: . * : * **.: : .. * . ***:: :: :**: * ** **:.:::*.*:: : *. . .*:* . :.:*.* * .. .: * : .*:.:*:.: ", "identical_positions": 138, "similar_positions": 219, "identity": "20.41%" }, { "cls_id": "homologset.agr.MGI:1929713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96MC4-1", "uniprot_id": "C295L_HUMAN", "id": "Q96MC4-1", "name": "CEP295 N-terminal-like protein", "aln": "MCSGWSSSVIWRHTQFAVERCGFCGSSGPGAPLEPSTLGSKHLPWEAVSAGFADRNRNMDGAMWLSLCPDNEDLLWRKKHKLLQARGKGDLALQRRADAKLWKNYQLQRLAEELRRGYQEAQHLHVGGLDRLQSARLLGWGGGRARENEPDSQGPIQRRSARPPRAKEKHRAALSEERSCREELGQQHPRHSRPRKTAASPEKPQTTKATGRMNSHLAPPEKRKGRPEPSTKSGGGRCAIHPRRSKGADLERSNPLVAAVGEIGLVEEKEKGTARAGRRQLGKGAVCFVPALTSRSQGQSLEGKLRDLGQLWPADSSCRREAVSPASQCTLREKNKWQKELELAFEELFNINRKLKKHLCLYLALKPRMDQRPGEGHAFSEMQECGAGTPRGKKMADPEMLPAGEPRSPAEEEAQQAASKTDLKTFMGKAQNQKYQGTVKPTFRNGSQTLSPEAGIFINKEDSLLYSTESGQETPKLGTLAEGSLQLHLQDQADRVGS-TASRQRQKAEMEQRRQKQLESLEQMEHPDMSLEIHYKAELEKERREQRRARLAHLKSSST--RAQERERGSELSTTSPSGTSLADDDRHSQMIRDQQQQILQQNRLHKQFLEEARKCLREFQNIC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q497N6-1", "uniprot_id": "C295L_MOUSE", "id": "Q497N6-1", "name": "CEP295 N-terminal-like protein", "aln": "------------------------------------------------------MQRDTERAAQLSPSSEDEALVLRQKPLEMPAQEEDSTTLQQ------WKARQLQRLAEELKAEWQEARLQQVRQAERLYLSHLLDEAAERSMGNDPSVHEQNQRRTAKHTRAKERNRAAFREERGRREEHPRQHP---KSRKKAPCSERRSSAKARG-----PASGEKGKRRRVSSSKDHDG--YQGPRVTRRVGVAKLNPFFD--GDTDCMEDVQKEFFREGRRPSAKG--------THNLRDQSLQGKTTALTQPLLHGPTCKQEAAAQEPPSKYN-KNLWHKEIESTFEELFNMNRKLKKHLNLHLEQRLKADQNPDEQQSYSEIRSETFGTPREERTEEVET--AEESGSPTEVETTEMWSKVNLKQILSDSEYPRYQQIAKYPLKSES-LVPVKAGTSREQDDLLSLSPESGQEPPKSPLLEDESLKPYLQKQADSVASWMALRQKQKAELEQRRQK--ALLELTEHPNMSLEIHYKAELEEERRARRRMRLALLKSNSTGICALPPDR-NNLSLDN----GLLDEDKQNQMIRDLQQQILEQNKLHQEFLEKARKRLQEFQKSF", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : * ** ..::* *: *:* : *: :.. :**: ** *********: :***: :* :** ::**. .. *: *:*. : ***:*: .****::***: ***. *** :*** :.**.*...*: .::** * *. ** * * .*:*. .* ** :: ..: : **:. *: . :*: :* * *** .** * . :.***:** * * ..:*::**.: . .. . ** *:**:* :******:******** *:* : : **.*.* :::**::. **** :: : * * *. **:* *: : **.:** ::..:: :** .* .::. * :. :** :::* * *.*****.** * : **: :**.*** *.* * **:****:****** ** ***:************:*** :** *** ***.** * :* .:** . .* *:*::.***** *****:**:**::***:*** *:***: ", "identical_positions": 235, "similar_positions": 153, "identity": "37.66%" }, { "cls_id": "homologset.agr.MGI:1929721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5P2-1", "uniprot_id": "RRS1_RAT", "id": "A1A5P2-1", "name": "Ribosome biogenesis regulatory protein homolog", "aln": "MEGQSVEELLAKAKQEEAEKLQRITVHKELELEFDLGNLLASDRNPP--TVLRQAGPSPEAELRALARDNTQLLVNQLWQLPTERVEEAVVAR-----------LPEPATRLPREKPLPRPRPLTRWQQFARLKGIRPKKKT-NLVWDEVSGQWRRRWGYKRAR-DDTKEWLIEVPGSADPMEDQFAKRIRAKKERVAKNELNRLRNLARAHKMQMPSSAGLHPTGHQSKEELGRAMQVAKVSTASVGRFQERLPKEKAPRGSGKKR-----KFQPLFGDFAAEKKNQLELLRVMNSKKPQLDVTRATNKQMREEDQEEAAKRRKMSQKGKKKGGRQGPSGRRKGGPPSQGEKRKGVLGGKKHSRPPALGGKKKGVPHHGGKRRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYH6-1", "uniprot_id": "RRS1_MOUSE", "id": "Q9CYH6-1", "name": "Ribosome biogenesis regulatory protein homolog", "aln": "MEGQRVEELLAKAEQEEAEKLQRITVHKELELEFDLGNLLASDRNPP--TVLRQAGPSPEAELRALARDNTQLLINQLWRLPTERVEEAVVAR-----------LPEPATRLPREKPLPRPRPLTRWQQFARLKGIRPKKKT-NLVWDEASGQWRRRWGYKRAR-DDTKEWLIEVPGSADPMEDQFAKRTQAKKERVAKNELNRLRNLARAHKMQMPSSAGLHPTGHQSKEELGRAMQVAKVSTASVGRFQERLPKEKAPRGSGKKR-----KFQPLFGDFAAEKKNQLELLRVMNSKKPRLDVTRATNKQMREEDQEEAAKRRKMSQKGKRKGGRQGPSGKRKGGPPGQGEKRKGGLGSKKHSWPSALAGKKKGVPPQGGKRRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15050-1", "uniprot_id": "RRS1_HUMAN", "id": "Q15050-1", "name": "Ribosome biogenesis regulatory protein homolog", "aln": "MEGQSVEELLAKAEQDEAEKLQRITVHKELELQFDLGNLLASDRNPP--TGLRCAGPTPEAELQALARDNTQLLINQLWQLPTERVEEAIVAR-----------LPEPTTRLPREKPLPRPRPLTRWQQFARLKGIRPKKKT-NLVWDEVSGQWRRRWGYQRAR-DDTKEWLIEVPGNADPLEDQFAKRIQAKKERVAKNELNRLRNLARAHKMQLPSAAGLHPTGHQSKEELGRAMQVAKVSTASVGRFQERLPKEKVPRGSGKKR-----KFQPLFGDFAAEKKNQLELLRVMNSKKPQLDVTRATNKQMREEDQEEAAKRRKMSQKGKRKGGRQGPGGKRKGGPPSQGGKRKGGLGGKMNSGPPGLGGKRKGGQRPGGKRRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8I937-1", "uniprot_id": "Q8I937_DROME", "id": "Q8I937-1", "name": "Ribosome biogenesis regulatory protein", "aln": "MD--VVKEVLAKH-QKELDKYKPITVEKHLECRLDVGSLLITDPND---FDDRELRDNKEEYLTALTRENTQLLVNAIWELPTERVDESIVAK-----------LPEPTTVLPRLRKPPGPRPLTKWEKFAKEKGISKKKKD-KKTYDETMDKWVPTYGFKRAEAEKAKDWVLEVPQNADPNTDMFQKKIDLRNEKVAKNEIQRMKNIVRAKKIDMPRSGYLGPEAASS-SQLLTAVTVAKSSTASVGKFQNKLPKEKEARGLGIKELIPGGKRKQSHITQTPEKEANLDLIKSVLNKKPKLDVSKAVSMEKRDNRLAREAEAE--NEPGK-KGGKK-PKG--KGSRKAVGKKSKGNRGQRAP-------GKK---AQAGRKRR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08746-1", "uniprot_id": "RRS1_YEAST", "id": "Q08746-1", "name": "Regulator of ribosome biosynthesis", "aln": "-------------MSAEDYKNLPVTVEKPIPVVYDLGNLAAFDSNVLDKNDLDSSNARREEKIKSLTRDNVQLLINQLLSLPMKTTTESVGGTGGQSSVMTLLQLPDPTTDLPREKPLPKAKAMTKWEKFAAKKGIKPKERAGKMIYDEASGEWVPKWGYKGANKKLDDQWLVEVDD----------------KVKGTDNELIDPRTLNRAERKRLVK----------------------KNEKQQRRNMKNAL-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :**.* : *:*.* * * * : :*:*:*.***:* : ** : . *:: . **:*:* *** : * .:.:*:*::** *** *:: : :**. .:* :*:: *. . .:*::** : : :.**: :.: **.: : * .. . .::: * ", "identical_positions": 51, "similar_positions": 62, "identity": "13.25%" }, { "cls_id": "homologset.agr.MGI:1929722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1K3-1", "uniprot_id": "APC5_RAT", "id": "A1L1K3-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-------------MMTNGVVHANLFGIKDWVTP--------------YKIAVLVLLNEMGR------TGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDLEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMD---REDGER-QMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-ADSYVLLEHSVKKAVHFGLP-------------RAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLSAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAILDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLTEAKNYFAKVDCRERIRDVSYFQARLYHALGKTQERNHCAMVFRQLHQELPSHGVPLINHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTZ4-1", "uniprot_id": "APC5_MOUSE", "id": "Q8BTZ4-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-------------MMTNGVVHANLFGIKDWVTP--------------YKIAVLVLLNEMGR------TGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDMEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMD---REDGEK-QMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-ADSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLNAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKDRFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAVLDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLSEAKNYFAQVDCRERIRDVAYFQARLYHALGKTQERNHCAMIFRQLHQELPAHGVPLINHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX4-1", "uniprot_id": "APC5_HUMAN", "id": "Q9UJX4-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-MASVHESLYFNPMMTNGVVHANVFGIKDWVTP--------------YKIAVLVLLNEMSR------TGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDMEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMELTSRDEGER-KMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-SDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFK7-1", "uniprot_id": "A0A8M1PFK7_DANRE", "id": "A0A8M1PFK7-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-MASVHESLYFNPMMTNGVVHANIFGIKDWVTP--------------YKIAVLALLYEMST------TKP--MALLDRRRLNKLILPLQQGPDLTLEQFLKIVEECCLRMVN----AVKLRLFLMADGELQDMEHFFTIL-PSAFSDSEP--FKTSVVGLFMRQMLLAYNKLSFSQVYKLYKSLQQFCHRGN---QPELSALPAEDMELTSNEDPSADHIDKDELDTPSLHQSELSRSEESQGPLSQ---KQAEYFLARQAYLLKNDENKAMSPAKLQDELNNILKFNPDFAEAHYLSYLNSLRVQDIYIS-THSLLHYFDRL-ILSGAEGKSNGDEGYGRSLRYAVLNLATLHCRFGHYHQADLALQEAIRIAQEANDHVCLQHCLSWLYTLEQMRGSDSVVLTEDSVKIAAHFCLPYLASLGIQSLVQQGAKQGMPANKLLDALRGTDIMHWKQSLSELIEISLAQTTSIWRMYGKSTMAQQQAQLLLNMNSLEPVNFSVQQNNTEAFAVALCHLAELHAEQGLYPVVTDIMKHLKQQFPPHTQHAKLWMLCDLKIQFEKAMNDGKYHLAEPHVTAITALNSTEGMYRKAQLLKALNQTTEASKILQQLQQQCEKSKNTQMSIRVMLASAELHWDSSGFATALPLLLQALALSRQHNLQSLTSETLLHLAFTQLMLGISEQALGLVQDVLESVLAHGSLMDKGRALLLAARCQMASAGAAAQEHRLSAVELAVHTLDEAAVYFSRLDCKERMRDIYYLQARLHQTLGNISQRNRCAMLFRLLDQELPSSRMTVVNRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZL2-1", "uniprot_id": "Q9VZL2_DROME", "id": "Q9VZL2-1", "name": "Anaphase-promoting complex subunit 5", "aln": "MILCLHFAGKSKIGFRGPKLTMNLFEELDTLDPSFKLEPPRIETPTAHKITVLILLKQYVINKKNCLDTGISMRTQRRRMFYMLVFKLIQEQDKSYNELHSLLTTGKYKLDTLMLESFEKAMSEFCAGSIEALFDFSEIQNIDEILNENYGISQFSMVGVYVRRVGVVLERLSFPEMMDMYKNVCSYYERGVRAAASGSRMAVAGGILHREETPPPNPITEKPEDPKPKKKVEAVARIAQERNPLSKWAPKQAKFFINKQSELLENNERKALPPLELQKKVQEIIHDLPLTTTPYFLGYMNQLRVRDYYNA-LSALHRALDRS-PVR----LMSQEKGY----QYFCVNLAVLHATFGHRDEALAALRESIMLAQEHGDKRSLNLANTWYCLLRDEL-PLSAVQKSVQDANEVDGSLLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDNLTNRNNFADHASEALALRSAVWSAYGRHELAALYSQVLLTGR-------DRFGSGSAGLGSALASFALWLQLQGEPQLSKVLLHHAKQRFP-RLPSAEGWMISQCHVVIQAGIYQCRWHDALKACDQLYLIDPSDSLFQRASIYVAKREFFNARRLLDKLAVQDNIPFLLRMRVQVLLGYCGMANGRFSSETTMLLLRVSEEMS-EAQMDYELALVDLLLALQLLLLGMPQKAYQAIKRCMHDIHINGGLYERAKTDFVFVRCLLAVNQNDAEKRKAQLLKSQVI-LQRAAQSFKKLSAHAKVLDVYVFLAQRFNEFGDRNLRNKYAGEFRRYFTDHPIPREYLGSP-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08683-1", "uniprot_id": "APC5_YEAST", "id": "Q08683-1", "name": "Anaphase-promoting complex subunit 5", "aln": "------------------MSKYGPLGITNFITP--------------YDLCILILIHAHCS------------QDNGISVPTAVFLRLISPTRPSLEWNPLLKDNSNLRSSS-----------IVPPPVLPILDNIIRILLDDKDG---------NKIALTLMGYLEAIN--GLDSINRLMMDLEKNCLVN----------------------NYRSMKMRTTSTRRQMTRASFLGT-------------FLSTCIRKYQIGDFEMRETIWINLQNFKTVFKHTPLWLRFKDNVHIQKVKNCLLANDEISVEDQQMVEFFQHFNNGNDADSKTMNEENYG-----TLISIQHLQSIVNRQIVNWLDNTEFNLMGQEETSSTYEEQSGLVFDLLDTLSLNDATKFPLIFILKYLEAIKENSYQTALDSLHNYFDYKSTGNSQNYFHISLLSLATFHSSFNECDAAINSFEEATRIARENKDMETLNLIMIWIIN-----FIEVHPEYANRFYITVEQIIKYLKNSS--DVEDANIFSNAYKFETLLSMVKESKTAEVSSSLLKFMAITLQNVPSQNFDLFQSLVSYEVKFWKELGYESISDVYEK-FLSKTSSSSLRNYDSSIINQDIKVAFKALEEDDFLKVKQYLLKSESLELDYDQKINLKYLRVKYLVKIGDYDLSMRLINQYVKECCEEVADSNWRFKFEIESINVLLLSDVGIRSLPKIIKLIDEYKEIGNPLRCVILLLKLCEVLIQVGKSMEAECLISCNLSTILEFPFVRKKTDELLESLSVEEDRDVQMT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : * :.: :* *: :.: * . : . : : . . : : .: . . :.: : . . .: .: : : . . . . : . :. : : * :: * : .:: .:. : * * ..* : . ::: ::.* :.: *:. ..: * :.** . : . * : . . : : . : .: : : : . : :: . . : : :: : .. : :* .: .: : : : . : : : : : : : : : . . : : :. : : : :. : .:: . : *.: . . . . . .: : . :. : . : * . : . :: . . :. . . . ", "identical_positions": 18, "similar_positions": 169, "identity": "2.25%" }, { "cls_id": "homologset.agr.MGI:1929735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYZ6-1", "uniprot_id": "A0A8I5ZYZ6_RAT", "id": "A0A8I5ZYZ6-1", "name": "Ankyrin repeat and SOCS box protein 1", "aln": "MCPSLVLEKHMFCSRSSP-SAGPNLKEWLREQFCDHPLEHCEDTRLHDAAYVGDLQTLRNLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTEILLEAGADPNGSRHHRSTPVYHASRVGRGDILKALIRYGADVDVNHHLTPDTRPPFSRRLTSLVVCPLYISAAYHNLQCFRLLLQAGANPDFNCNGPVNTQEFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESLGPEARGRRKIDPEALQVFKEARSIPRTLLSLCRVAVRRALGKYRLHLVPSLPLPDPIKKFLLYE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV74-1", "uniprot_id": "ASB1_MOUSE", "id": "Q9WV74-1", "name": "Ankyrin repeat and SOCS box protein 1", "aln": "MAEGGTGPD----GRAGPGPAGPNLKEWLREQFCDHPLEHCDDTRLHDAAYVGDLQTLRNLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTEILLEAGADPNGSRHHRSTPVYHASRVGRDDILKALIRYGADVDVNHHLTPDTRPPFSRRLTSLVVCPLYISAAYHNLQCFRLLLQAGANPDFNCNGPVNTQEFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESLGPEARGRRKMDPEALQVFKEARSIPRTLLSLCRVAVRRALGKYRLHLVPSLPLPDPIKKFLLYE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y576-1", "uniprot_id": "ASB1_HUMAN", "id": "Q9Y576-1", "name": "Ankyrin repeat and SOCS box protein 1", "aln": "MAEGGSPDG-----RAGPGSAGRNLKEWLREQFCDHPLEHCEDTRLHDAAYVGDLQTLRSLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGSCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTQILLEAGADPNGSRHHRSTPVYHASRVGRADILKALIRYGADVDVNHHLTPDVQPRFSRRLTSLVVCPLYISAAYHNLQCFRLLLLAGANPDFNCNGPVNTQGFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESLGPESRGRRKVDPEALQVFKEARSVPRTLLCLCRVAVRRALGKHRLHLIPSLPLPDPIKKFLLHE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N182-1", "uniprot_id": "A0A8M1N182_DANRE", "id": "A0A8M1N182-1", "name": "", "aln": "MTDSENVAV------EGCGAAGRNLTHWLQEQFGNRPLEQSEDTRLHNAAHLGDLDTLRTLLQEDCFRQRINQKLIWSCGLLPCTPLRIAAMMGRSDCVAFLISQGADVDLVDVKGQTALFMAVVNGHLDCVKILLEAGADPNGSRHHRSTPIYHAAQVGRADIMLELIRFHADVDIDHRLEQKVIFR-TRTLTTLAACPLYISAAYHHLPCFRMLLKAGANPDYNYNGPVNRDALVKGRASCMLDAVLRLGCDPVFVSLLLDHGADPHVVHWDELDPDTMIRLKVNVEALCVYQEARRNPQRLMNLCRITIRKIFGKKHMSCISSLPLPDTIITFILHND", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . .** **..**:*** ::***:.:*****:**::***:***.****:.:*.***:* :*.** ********** *:..** *** :**:************::*******:..:*******************:***::*** **: ***: ****::*:* .. :* **:*..**********:* ***:** ******:* ***** : : :* ..*::***** **:..*****::.**: ::*:*:.*.*:: * *:: *** *::*** *: *: ***:::*: :** :: :.******.* .*:*:: ", "identical_positions": 189, "similar_positions": 93, "identity": "55.43%" }, { "cls_id": "homologset.agr.MGI:1929742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKW1-1", "uniprot_id": "TIM22_RAT", "id": "Q9JKW1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "--MAAAKAGASAPEAAG------SAE-APLQYSLLLQHLVGDKR-QPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAVLACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAREVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGVKAGAIGCGGFAAFSAAIDYYLR-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ85-1", "uniprot_id": "TIM22_MOUSE", "id": "Q9CQ85-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "MAATAPKAGGSAPEAAG------SAE-APLQYSLLLQYLVGDKR-QPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAVLACVGGFVLGGAFGIFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGVKAGAIGCGGFAAFSAAIDYYLR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y584-1", "uniprot_id": "TIM22_HUMAN", "id": "Q9Y584-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "MAAAAPNAGGSAPETAG------SAE-APLQYSLLLQYLVGDKR-QPRLLEPGSLGGIPSPAKSEEQKMIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCGGFAAFSAAIDYYLR-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FA60-1", "uniprot_id": "E7FA60_DANRE", "id": "E7FA60-1", "name": "Mitochondrial import inner membrane translocase subunit TIM22", "aln": "MAAPAKSTDASLSVTAGHSANVSSAENVSLQYSLILDHLIGDKR-QIKDLNPTVMGALPSPQKTDEQKMIERGMESCAFKSLIACVGGFVLGGAFGVFTAGIDANVGLDPKDPLRTPTAREVLKDMGQRGMSYAKNFAIVGAMFSCTECLIESHRGKSDWKNAVYSGCITGGAIGFRAGLKAGVLGCGGFAAFSAAIEYYLR-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IN78-1", "uniprot_id": "TIM22_DROME", "id": "Q8IN78-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "MSVLPNAGNNESSVTAP------KMFGDPDLDRMAMEYVGNMQRYRENIIIPKSNG--PVKIKTNEEKFIETAVESCGFKCTMACVMGYGLGAALGLFSASVNPNM-ADPFANEKKQTAREVFREMRSTTHSYAKNFALIGCVFSAVECTIESHRGVTDWKNGTYAGGITGGLIGLRAGVKAGIIGGLGFAAFSTAIDYYMYSR-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12328-1", "uniprot_id": "TIM22_YEAST", "id": "Q12328-1", "name": "Mitochondrial import inner membrane translocase subunit TIM22", "aln": "MVYTGFGLEQISPAQKKPYNELTPEEQGERGAEMIMNFMTSCPG---KSVVSGVTGFALGGVLG--LFMASMAYDTPLHTPTPANTAATATAGNIGVG--GISRTVQQISDLPFR-QQMKLQFTDMGKKSYSSAKNFGYIGMIYAGVECVIESLRAKNDIYNGVTAGFFTGAGLAYKAGPQAALMGGAGFAAFSAAIDLYMKSEDGRPPQNDFKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::.: . . : . * : . . :: .. * . . .. :*: .:. .: . : : : :* . * ****. :* ::: .** :** *. .* *.. :* :**. :. :** :*. :* ******:**: *: ", "identical_positions": 33, "similar_positions": 57, "identity": "15.35%" }, { "cls_id": "homologset.agr.MGI:1929743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0L0-1", "uniprot_id": "ASB2_MOUSE", "id": "Q8K0L0-1", "name": "Ankyrin repeat and SOCS box protein 2", "aln": "----------------------------------------------------------MATEISTRGRQ-RAIGHEEYSLYSSLSEEELLQMAIEQSLADKTRG---------------PTPAEASASSQTNHQP--GHFHPWTRSPSSPENPPAR-------APLGLFQG-------VMQKYS-SNLFKTSQMAAMDPVLKAIKEGDEEALKIMIQD-GKNLAEPNKEGWLPLHEAAYYGQLGCLKVLQQAYPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRILVRYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQASDSASALYEASKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGN-----------------YRIVQMLLPVTSRTRVRRSGISPLHLAAERNHDAVLEALLAARFDVNAPLAPERARLYEDRRSSALYFAVVNNNVYATELLLLAGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPA-PRPG-RFHDAPVDDKAPSVVQFCEFLSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2S6-1", "uniprot_id": "ASB2_RAT", "id": "Q5U2S6-1", "name": "Ankyrin repeat and SOCS box protein 2", "aln": "----------------------------------------------------------MSTEISTRGRQ-RAIGHEEYSLYSSLSEEELVQMAIEQSLADKTRG---------------PTPAETSVSSQTNHQP--GHIHPWTRSSSPPESPPAR-------APLGLFQG-------VMQKYS-SNLFKTSQMAAMDPVLKAIKEGDEEALKAMIQD-GKNLAEPNKEGWLPLHEAAYYGKLGCLKVLQRAYPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQASDSASALYEACKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGN-----------------YRIVQMLLPVTSRTRVRRSGISPLHLAAERNHDAVLEALLAARFDVNTPLAPERARLYEDRRTSALYFAVVNNNVYATELLLLAGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPA-PRSG-RFNDAPVDDKAPSVVQFCEFLSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96Q27-2", "uniprot_id": "ASB2_HUMAN", "id": "Q96Q27-2", "name": "Ankyrin repeat and SOCS box protein 2", "aln": "----------------------------------------------------------MATQISTRGSQ-CTIGQEEYSLYSSLSEDELVQMAIEQSLADKTRG---------------PTTAEATASACTNRQP--AHFYPWTRSTAPPESSPAR-------APMGLFQG-------VMQKYS-SSLFKTSQLAPADPLIKAIKDGDEEALKTMIKE-GKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGN-----------------YRIVQMLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPA-PQPSSRFNDAPAADKEPSVVQFCEFVSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I5B0-1", "uniprot_id": "A0AC58I5B0_DANRE", "id": "A0AC58I5B0-1", "name": "", "aln": "MVALQFALSSHSKKVTVSSPDWASWRVCVEFACSPRGGLGFFQELRFPPQSKDIGTIMAATHVSLPGTTGTNLEFADYSLYSNLSDDELLHLAIERSLADAHSSGSGTENLKTPAALNKPSSAAATAACQTPSRPPQQQQRQQTVQAACPANPPREKIDLENVCSVSHFVTGYGKPMVAYRRYDGSMQLVPEPEEELEPIAKAISEGDVGTVRLMVKQPGCNLLKPNKEGWIPLHEAAYYGQDQCVKILLRAQPGMINQRTLRDQTPLMLAVSRENLACVEILLEKGADPEIPNKEKETPLYKACEKENPALVAMLLNHGALVNKSCIQGWTALHESVCRNNVEICEMLMKAGAKVSLPNKYGITPIFVAAQSGKVEALRMLLKNGADLNSQASDGATALYEACKNGHEDIVEFLLSQNADANKAGKTGLLPIHIAAQRGKDGKDLLTFGCTRKNISATKIIAMLIPATSRARVRRSGISPLHLAAERNRNDIVEVLIEAGFDVNAMLSEDRSMMYEDRRSTALYFAVINNNIEATTMLLEAGANPNLDTFKPLLVALRQGCIQTVTLLVEHGADVNANIPTHPTSFPASVMFCMKYLSLLKYLMDNGCDALSCFNCVYGSNPHPPIKPRRNPRYDSDESREK--TCVLFCEVISTENYSRWSGPIIDVLLDYVGHVKLCARLVEHLDSYHEWQCIKEKAMPPRPLMQLCRLKIRTLLGINRLKKIHKLPVPPRLIKFLNHQEREYEM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.:* * : :*****.**::**:::***:**** . *:.* ::.:. * :* : * ..: * ..* . ..:. * . ::*. * : .. :*: ***.:** ::: *::: * ** :******:*********: *:*:* :* ** *:****:::*.: **..* :* *: **: **:*:*.**.:*********::*. * :*:.:.* .*: * :*********.**::*: ::*:..****. * *.***:*******::****:* * ***:*:****.*:*****.** **::*******.*****:.* ****:*:*:::*: :*: **:*.***:*:****:**********:: ::*.*: * ****: *: :*: :*****::******:***: ** :** **:** *.:.*****:*:**::*: **::***:::* *.****:***::**.** *****:*** ***. .**.*:**..**** *: . *:.. :* : * ***.:*: : ***:************:*:**:** **:**:.:* ***** ***** :****::*. :* *:* :..**:* ***::*:::: : ", "identical_positions": 326, "similar_positions": 198, "identity": "43.58%" }, { "cls_id": "homologset.agr.MGI:1929744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JZX9-1", "uniprot_id": "BORG1_MOUSE", "id": "Q8JZX9-1", "name": "Cdc42 effector protein 2", "aln": "MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGDDMFGDISFLQGKFHLLPGTAVEEAEEDGSFDLPFQFTRTTTVCGRELPDGLSPLLKNAISLPVIGGPQALTLPTAQAPPKPPRLHLESPQPSPQPSPQGAGNVDVWRIPEAGSPHNGMSPEPEAEEPFLSHASSLLSLHVDLGPSILDDVLQIMDHDLGRVQIPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQP4-1", "uniprot_id": "BORG1_RAT", "id": "Q5PQP4-1", "name": "Cdc42 effector protein 2", "aln": "MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGDDMFGDISFLQGKFHLLPGTAVEEAEEDGSFDLPFQFTRTTTVCGRELPGGLSPLLKNAISLPVIGGPQALTLPTTQAPPKPPRLHLESPQPSPKSSPQEAGNVDIWRVPEAGLPHNGMSPEPEAEEPFLSHASSLLSLHVDLGPSILDDVLQIMDQDLGRVQIPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14613-1", "uniprot_id": "BORG1_HUMAN", "id": "O14613-1", "name": "Cdc42 effector protein 2", "aln": "MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQGKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALTLPTAQAPPKPPRLHLETPQPSP----QEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSLLSLHVDLGPSILDDVLQIMDQDLDSMQIPT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************.******************* ** .****:**********:********.* ***********************:************:***** * .*.**:**:**:* *:.*::**. *******:************************:**. :****", "identical_positions": 182, "similar_positions": 21, "identity": "85.05%" }, { "cls_id": "homologset.agr.MGI:1929745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0X0-1", "uniprot_id": "BORG3_MOUSE", "id": "Q9Z0X0-1", "name": "Cdc42 effector protein 5", "aln": "MPVMKQLGPAQPKKRLDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPGAPPVVAPHSVAPP--------------AAPQPPVAVPSPADPLLSFHLDLGPSMLDAVLGVMD----------------AERSETTATKPDGDAHPRVQHPKTRCCSNADLQLDDVIGL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NZY7-1", "uniprot_id": "BORG3_HUMAN", "id": "Q6NZY7-1", "name": "Cdc42 effector protein 5", "aln": "MPVLKQLGPAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPPP--------------AVPQS--AAPSPADPLLSFHLDLGPSMLDAVLGVMD----------------AARPEAAAAKPDAEPRPGTQPPQARCRPNADLELNDVIGL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R2T1-1", "uniprot_id": "F1R2T1_DANRE", "id": "F1R2T1-1", "name": "", "aln": "MPLHKSS------RAPRLDPTMISAPLGDFRHTMHIGRGGDAFGDTSFLSSHGPSSPDPNTAQPVTATPSMTENQDIETNHNDEMKYVEDSSPSELRHSDSVSSFDLDLDLGPSILGDVLGVMDGLTMGSCKGNEEVFTSGSKDAMMSSRNVGNELNERMRMESLSRELRDEQLNEVNGIKSKGLRPKVRFSDKRDEIIGRQEVIEGLEAEGEEMRPNKGMQEISGRTAFDKDPRQEEMVNRREENSPSLSSSASSEYEGVSPLDRRREDQHLSDSDSEEETANGEQGYTFEDELDDEIGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *. : .. ***********:*:************** ** ..* * *. *. * . ... * : . :.:.******:*. ****** . : ::: .: :: . * :*::* *: ", "identical_positions": 54, "similar_positions": 37, "identity": "17.94%" }, { "cls_id": "homologset.agr.MGI:1929749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA67-1", "uniprot_id": "A0A0G2KA67_RAT", "id": "A0A0G2KA67-1", "name": "", "aln": "MGGRGLHYPQFFRNLWRSCWSSTPPTFFPSETRKRRKGRTPVLKGTGMVTTVSTLIKKMDFTEAYSDTCSTVGLAAREGNVKILRKLLKKGRSVDVADNRGWMPIHEAAYHNAVECLQMLIHTDSSENYIKTKTFEGFCALHLAVSQGHWKVTQILLEAGADPNTTTLEETTPLFLAVESGQIDVLKLLLQHGANVNGSHSMCGWNSLHQASFQGNAEAIKLLLKQGADRECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSNGADPDLYCNEDNWQLPIHAAAQMGHRKTLDLLIPLTNRACDSGPDKVSPVYSAVFGGREECLETLLQNGYSPDAQMCLVFGFSSPLCMALQKDCEFSGVVNILLKYGAQLNELHLAYCLKYEKFSMFCCFLKKGCLVVPWNHTSEFVSYAVKAQTKYKAWLPHLLLAGFDPLILLCSSSWVDSVSDDILIFTLEFSNWKRLPPAVEKMLSVRANSSFALQQHMASVPSLTHLCRLEIRSSLKAEHLHSDIFIHQLPLPRSLQSYLLYEEVLRMNGILEPATNHDGEIREAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV72-1", "uniprot_id": "ASB3_MOUSE", "id": "Q9WV72-1", "name": "Ankyrin repeat and SOCS box protein 3", "aln": "----------------------------------------------------------MDFTEAYSDTCSTVGLAAREGNVKILRKLLKKGRSVDVADNRGWMPIHEAAYHNAVECLQMLIHTDSSENYIKAKTFEGFCALHLAVSQGHWKITQILLEAGADPNETTLEETTPLFLAVESGRIDVLKLLLQHGANVNGSHSMSGWNSLHQASFQGNAETIRLLLKQGADRECQDDFGITPLFVAAQYGKLESMSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTETLDLLIPRTNRACDTGPDKVSPVYSAVFGGREECLEMLLQNGYSPDAQMCLVFGFSSPLCMAFQKDCDFSGIVNILLKYGAQLNELHLAYCLKYEKFSMFCSFLKKGSLMVPWNHTSEFISYAVKAQTKYKAWLPHLLLAGFDPLILLCSSSWVDSASDDILIFTLEFSNWKRLPSAVEKMLSVRANSSWALQQHLASVPSLTHLCRLEIRASLKAEHLHSDIFIHQLPLPRSLQNYLLYEEVLRMNEILEPAANQDGETSKAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y575-1", "uniprot_id": "ASB3_HUMAN", "id": "Q9Y575-1", "name": "Ankyrin repeat and SOCS box protein 3", "aln": "----------------------------------------------------------MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSSPVCMAFQKDCEFFGIVNILLKYGAQINELHLAYCLKYEKFSIFRYFLRKGCSLGPWNHIYEFVNHAIKAQAKYKEWLPHLLVAGFDPLILLCN-SWIDSVSIDTLIFTLEFTNWKTLAPAVERMLSARASNAWILQQHIATVPSLTHLCRLEIRSSLKSERLRSDSYISQLPLPRSLHNYLLYEDVLRMYEVPELAAIQDG------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:****************:*****************************:********::******** ************.******:.*********** **************.*:****:***************.*********** *** *:***::**::**********************:**************************************.***********.************* : ****** ******:* :************:*:*** **:******** *********:***:****:* *:**********:***************:* **:**. : **** **:.:*:***:*** ******:**********. **:**.* * *******:*** *..***:***.**..:: ****:*:*************:***:*:*:** :* ********:.*****:**** : * *: :** ", "identical_positions": 423, "similar_positions": 66, "identity": "72.56%" }, { "cls_id": "homologset.agr.MGI:1929751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV71-1", "uniprot_id": "ASB4_MOUSE", "id": "Q9WV71-1", "name": "Ankyrin repeat and SOCS box protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------MDGITAPISKAGAAKLVKKDFLEALKTNDFGKLKAILIER-------QIDVDTVFEVEDENMILASYKQGYWLPS-----------------------------------------------------------YKLKSSWATGLHLSVLLGHVECLMVLLDHNATINCRPN-------------------------------------GKTPLHVACEIANLECVKILCDRG-AKLNCYSLSGHTALHFCTTPSSILCAKQLVLRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVENGAIVDSMNAH-------------------------METPLAIAT----------------------------------------------------------YWA----------------------------------LRFKEQEYSREHHLICRTLLDNNAEVNARDDDFKSPLHKAAWNCDHV-LMHMMLEAGAEANLMDINGCAAIQYVLKVTS--------------------------------------------------------------------------------------VRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHS----------------CPKAIEVVVNAYEHIRWNIKWRRAIPDDD------LEKHWDFYHSLFKVCCNTPR------------TLMHLSRCAIRKALHNRCHKAIPMLSLPLPLKKYLLLEPEGIIY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y574-1", "uniprot_id": "ASB4_HUMAN", "id": "Q9Y574-1", "name": "Ankyrin repeat and SOCS box protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------MDGTTAPVTKSGAAKLVKRNFLEALKSNDFGKLKAILIQR-------QIDVDTVFEVEDENMVLASYKQGYWLPS-----------------------------------------------------------YKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPN-------------------------------------GKTPLHVACEMANVDCVKILCDRG-AKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAH-------------------------METPLAIAA----------------------------------------------------------YWA----------------------------------LRFKEQEYSTEHHLVCRMLLDYKAEVNARDDDFKSPLHKAAWNCDHV-LMHMMLEAGAEANLMDINGCAAIQYVLKVTS--------------------------------------------------------------------------------------VRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHS----------------CPKAIEVVVNAYEHIRWNTKWRRAIPDDD------LEKYWDFYHSLFTVCCNSPR------------TLMHLSRCAIRRTLHNRCHRAIPLLSLPLSLKKYLLLEPEGIIY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40480-1", "uniprot_id": "HOS4_YEAST", "id": "P40480-1", "name": "Protein HOS4", "aln": "MNETTTKQPLKKRSLSSYLSNVSTRREELEKISKQETSEEEDTAGKHEQRETLSEEVSDKFPENVASFRSQTTSVHQATQNNLNAKESEDLAHKNDASSHEGEVNGDSRPDDVPETNEKISQAIRAKISSSSSSPNVRNVDIQNHQPFSRDQLRAMLKEPKRKTVDDFIEEEGLGAVEEEDLSDEVLEKNTTEPENVEKDIEYSDSDKDTDDVGSDDPTAPNSPIKLGRRKLVRGDQLDATTSSMFNNESDSELSDIDDSKNIALSSSLFRGGSSPVKETNNNLSNMNSSPAQNPKRGSVSRSNDSNKSSHIAVSKRPKQKKGIYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFESVDDESEFDDEEDQKILREIKKRLSIAAKKWTNRAGIHNDKSKNGNNAHTIDQPPFDNTTKAKNEKAADSPSMASNIDEKAPEEEFYWTDVTSRAGKEKLFKASKEGHLPYVGTYVENGGKIDLRSFFESVKCGHEDITSIFLAFGFPVNQTSRDNKTSALMVAVGRGHLGTVKLLLEAGADPTKRDKKGRTALYYAKNSIMGITNSEEIQLIENAINNYLKKHSEDNNDDDDDDDNNNETYKHEKKREKTQSPILASRRSATPRIEDEEDDTRMLNLADDDFNNDRDVKESTTSDSRKRLDDNENVGTQYSLDWKKRKTNALQDEEKLKSISPLSMEPHSPKKAKSVEISKIHEETAAEREARLKEEEEYRKKRLEKKRKKEQELLQKLAEDEKKRIEEQEKQKVLEMERLEKATLEKARKMEREKEMEEISYRRAVRDLYPLGLKIINFNDKLDYKRFLPLYYFVDEKNDKFVLDLQVMILLKDIDLLSKDNQPTSEKIPVDPSHLTPLWNMLKFIFLYGGSYDDKKNNMENKRYVVNFDGVDLDTKIGYELLEYKKFVSLPMAWIKWDNVVIENHAKRKEIEGNMIQISINEFARWRNDKLNKAQQPTRKQRSLKIPRELPVKFQHRMSISSVLQQTSKEPFW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * ::.:.:: *:. :: :. . .:*:*:* : *: : : **:*:: ::. *. .:..* .* *:: * . : :: :.:*. * *:* *::**: .: : ** : :.* .:* . :*:**** .: . * .: *: .**:**:*: : :*** *: * ::* : :::** **: ::. *:**: **: ** :. . *. : :* ** . * *:. .* . .*: ::::*****:.. * :* :*: *. : *: :: .: :* *.... *. :::* . . .** : * : * . : . : ::: *** . :.*: .: : : :*.:.::.:: : . .: : :* .::. * : * : ", "identical_positions": 88, "similar_positions": 167, "identity": "8.13%" }, { "cls_id": "homologset.agr.MGI:1929760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC33-1", "uniprot_id": "B1WC33_RAT", "id": "B1WC33-1", "name": "", "aln": "MPILKQLVSGSVNSKRRSRADLTAEMISAPLGDFRHTMHVGRGGDAFGDTSFLTSKTGEPDGESLDEQATSS--KLSLLSRKFRGSKRSQSVTRGDREQRDMLGSLRDSSLFVKNAMSLPQLNEKEATEKDSSKLPKSLSSSPVKKADTRDGSPK-------SPHRNGATGPHSPDPLLDEQAFGDLMDLPVMPKVSYGLKHAESILSFHIDLGPSMLGDVLSIMDKDQWGSEEEGEEEGGIYRVKEGPGGIVQGPPMLEASP-RGRQESKASWDHASMLPHHALEDDGWAAVAPSPSSARSVGSHTTRDSSSLSSYTSGVLEERSPAFRGPDRVGAAPPRQPDKEFSFMDEEEEDEIRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM96-1", "uniprot_id": "BORG4_MOUSE", "id": "Q9JM96-1", "name": "Cdc42 effector protein 4", "aln": "MPILKQLVSSSVNSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLTSKAREADDESLDEQASAS--KLSLLSRKFRGSKRSQSVTRGDREQRDMLGSLRDSALFVKNAMSLPQLNEKEAAEKDSSKLPKSLSSSPVKKADARDGGPK-------SPHRNGATGPHSPDPLLDEQAFGDLMDLPIMPKVSYGLKHAESILSFHIDLGPSMLGDVLSIMDKDQWGSEEE--EEAGGYRDKEGPSSIVQAPPVLEVVPPLGRQESKASWDQASMLPPHAVEDDGWAVVAPSPSSARSVGSHTTRDSSSLSSYTSGVLEERSPAFRGPDRVAAAPPRQPDKEFCFMDEEEEDEIRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3Q1-1", "uniprot_id": "BORG4_HUMAN", "id": "Q9H3Q1-1", "name": "Cdc42 effector protein 4", "aln": "MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTEEAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEG---EGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPS-LPSHALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERSPAFRGPDRARAAVSRQPDKEFSFMDEEEEDEIRV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********.**:*****************************.**********.**: *.*.******.::* * *******************:*************:*****************:**.:***************: :*. : *:****:***************** ***::**.:*********:********************::*..** *.* : : ... *.*.** . * .***.**. * .* ** **:**:***..****.****:************* ***:*************. ** .*******.************", "identical_positions": 269, "similar_positions": 53, "identity": "74.72%" }, { "cls_id": "homologset.agr.MGI:1929763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5P0-1", "uniprot_id": "BORG5_RAT", "id": "A1A5P0-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGTGAPSMSLGKLSPVG-WVPSSHGKR----RLTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGR-SGNTHRSPRS--------FLARKLQQVRRVGVPPRRMASPAATSPAPPPISPIIKNAISLPQLNQATYDSLVVSKLSFDSTPASSTDGRSGYGLESGFCTISRLPRVEKHSSRDRDHDRDPDHSQDREQSSSPSEPNPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAN-------PPAPAANP-APTAKPPADAVTTLDTVTSLPAP--------------TASSPSSGRFPNGVTAVLGPVAEVKASPVGEGPQVPSKMAFDRR-GASWG-------AIRASRHYTEMDARRELAGVLPQVHGSWESLNEEWSAPPASSRAPVPSTVQANAFEFADADEDDEVKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W92-1", "uniprot_id": "BORG5_MOUSE", "id": "Q91W92-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGTGAPTMSLGKLSPVG-WVSSSHGKR----RLTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGR-SGNTHRSPRS--------FLARKLQQVRRVGVPPRRMASPAAPSPAPPPISPIIKNAISLPQLNQATYDSLVMGKLSFDSTPASSTDGHSGYGLESGFCTISRLPRVEKHSNRDR--DRDPDHSQDREQSSFPSEPTPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAETPVPTANPPAPAANP-APTAKPPAHAITTLDAVTSLPASAVTSL-----PAPAAASSPSRGHFPNGVTSVLGPAAEAKPSPVGEGPQVPSNMTFDRH-GASWGASRASWGASRASRHYTEMDARRELAGVLPQVHGSWESLNEDWSTPPASVRAPVPTSVQVNAFEFADAEEDDEVKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00587-1", "uniprot_id": "BORG5_HUMAN", "id": "Q00587-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGRGAATMSLGKLSPVG-WVSSSQGKR----RLTADMISHPLGDFRHTMHVGRGGDVFGDTSFLSNHGGS-SGSTHRSPRS--------FLAKKLQLVRRVGAPPRRMASPPAPSPAPPAISPIIKNAISLPQLNQAAYDSLVVGKLSFDSSPTSSTDGHSSYGLDSGFCTISRLPRSEKPHDRDR-------------DGSFPSEPG----LRRSDSLLSFRLDLDLGPSLLSELLGVMSLPEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASSTPHGHCPNGVTAGLGPVAEVKSSPVGGGPRGPAGPALGRHWGAGWD----------GGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTFEFADAEEDDEVKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8I7-1", "uniprot_id": "A0A8M1P8I7_DANRE", "id": "A0A8M1P8I7-1", "name": "", "aln": "------------MSLGKLPAIKGLVSTSQSRRRFKSELSVDMISPPLGDFRHTMHVGRGGDVFGDTSFLSNYGGSGHSDAQRCPDSPPGSKTTRFLSRTLQHVRKTPAPRPRGGS-RDFSSPPPPISPIIKNAISLPQLNLS--NGGLM-RTMLHTSTSSPDRPLCSYGLPSGFVTLPRFSRLDQ------SFAEAPESPR---TDSRRSSE---VSLSPSDSLS--SFTVDLGPSLMTEVLEIIDN-----------------------------------SCSLLKSREEED-----------------------EDQRS--AGSDRENQ--LSDDSVLRSVT----------------------------------ADVAIEPRRFQQAASMLARHFGGRAEEERQRPSSFRHTRTPYSFTETEEEIKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B274-1", "uniprot_id": "A0A8M2B274_DANRE", "id": "A0A8M2B274-1", "name": "", "aln": "------------MNLGKLSGLKGLVSHSSGKRRFKGDLTPEMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGAGNNADAESSTS---EKNEGFFTRTLRHVRKTPD-RPRGGS-KDLSPPPPAVSPIIKNAISLPRLDVDSPNGCPV-KVLFPSSPKTPENSTYLYGLESGFVTLPRLSRTERPAQGSSPSACPPEIHRGSLTDTNIPSLPCSDSISPSDSMN--SFTLDLGPSLMSEVFALIDSPMCEKPD-----------TISEKAQSVEYNSDSDATTSLVDSLLRED-----------------------DDGRTRLYGGEWKNSDFVNDESPKKSTTGDQLRS-------------------------FPIEDRGMEPESFQRAADVLARHYG--SGGLRNTNTNNSHRRAPYCYPDEDEEIKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.****. : *. * .:* *: :*** **************************:** . ... * *:::.*: **:. * .* *..**.:***********:*: :. : : : ::. :. *** *** *:.*:.* :: .: .. : ***: : :******::*:: ::. . . : : * : . . . . : *. .: : :. :. .: ::*:**", "identical_positions": 86, "similar_positions": 81, "identity": "19.91%" }, { "cls_id": "homologset.agr.MGI:1929772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQF6-1", "uniprot_id": "DPYL5_MOUSE", "id": "Q9EQF6-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "------------MLANSASVRILIKGGKVVNDDCTHEADVYIESGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKE-TSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVRE--KGVNSFQMFMTYKDLYMLRDSELYQVFHACRDIGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA--KMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKT-------LKVRGVDRTPYLG-DVAIVVHP-------GKKEMGTPLADTPTRPVT-RHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHU0-1", "uniprot_id": "DPYL5_RAT", "id": "Q9JHU0-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "------------MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKE-TSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVRE--KGVNSFQMFMTYKDLYMLRDSELYQVFHACRDFGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA--KMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKT-------LKVRGVDRTPYLG-DVAVVVNP-------GKKEMGTPLADTPTRPVT-RHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPU6-1", "uniprot_id": "DPYL5_HUMAN", "id": "Q9BPU6-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "------------MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKE-TSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVRE--KGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA--KMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKT-------LKVRGVDRTPYLG-DVAVVVHP-------GKKEMGTPLADTPTRPVT-RHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IPQ2-1", "uniprot_id": "Q8IPQ2_DROME", "id": "Q8IPQ2-1", "name": "dihydropyrimidinase", "aln": "MSTSPKPVKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKH-ESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKE--LGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS--EELDRSGVRACIKVKNPPGGKSSGFW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32375-1", "uniprot_id": "ALN_YEAST", "id": "P32375-1", "name": "Allantoinase", "aln": "----------MPINAITSDHVIINGANKPATIVYSTESGTILDVLEGSVVMEKTEITKYEIHTLENVSPCTILPGLVDSHVHLNEP--GRTSWEGFETGTQAAISGGVTTVVDMPLNAIPPTTNVENFRIKLEAAEGQMWCDVGFWGGLVPHN---LPDLIPLVKAGVRGFKGFLLDSGVEEFPPIGKEYIEEALKVLAEEDTMMMFHAELP--KAHEDQQQPEQSHREYSSFLSSRPDSFEIDAINLILECLRARNGPVPPVHIVHLAS----MKAIPLIRKARASGLPVTTETCFHYLCIAAEQIPDGATYFKCCPPIRSESNRQGLWDALREGVIGSVVSDHSPCTPELKNLQKGDFFDSWGGIASVGLGLPLMFTQGCS-----LVDIVTWCCKNTSHQVGLSHQKGTIAPGYDADLVVFDTASKHKISNSSVYFKNKLTAYNGMTVKGTVLKTILRGQVVYTNANGVSKTPLGQTLLDSRR-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::. : .: .. : ::.. :: . * *: :.: ::** :*. .*:: . . .. :.* **:**: **.* ::. * : :: : *: :: ** .: *:. :: * : *.:.* : : : .. : :.:. . . : .*** *. :. . .. *:*:..* :* : . . *: *:: :: * : . . : *::. * . .. * . * :. : . **: . . : * : * ** . *: .* :.::: :* :*: ..*::: ..: :** * * ***:*:::. :.:.** .: .:. ::.* :*. .: **:: .. *: ", "identical_positions": 63, "similar_positions": 156, "identity": "10.52%" }, { "cls_id": "homologset.agr.MGI:1929785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M7D3-1", "uniprot_id": "F1M7D3_RAT", "id": "F1M7D3-1", "name": "", "aln": "-----KMSRALGLALLALTCTVDLGQTSGFTENGLSLLSYQLCSYPMTRSVQKLQAVQTSYTAYVYCGGWIPWKKCPKTVYRTQYLEMNVPESRNVTDCCAGFEQLGLYCVLSRNRSREFASRPGVCPTAEPG----PFTSSCSLDTDCPGLQKCCAWPGGHRCVSPTPTGTERSIVG-WYNVTVLVKMGFEDLQREDPGLRNHTRLLYSLVTSALQPLNPAVHYLTSTGGKDTFTTVSWLLLGFPQRMTVANVSTMLDDMVNRVYEVISIQVQDVNECLHSELQACSEGKQCWNLEGSYQCVS---------------------PQQLNHTDKDCPPIRDFVALDVTSSSFHVSWSLNSTQNHTFHVQVYK-GREILRSTWTGDRTLAVPDLEAGVLYRVRTSYQGCRAN-ISATLVVKTDARVFQVTIRIMNRNLTEQILNCSSREFWNFSRQLFQEVENSFPQVISNMYRQGRLKMQIVSLKAGSLVVTLRLTLQDPDFLVNVGTLKPMLQPLSMSTVFQVDQQGTRVQDWDECAHSSEHDCHPAARCINLEGSYTCQCLT-ARDANPSRAGRVCEGDMVTPTGGGLSVETTKVKAAAVSMGITTFGPETLTLSPSSEHLRSTPAEGQASTLGPPSRRDGGSTARQDRNSTGQD----VEVPNVTQNPHTTRESQEHMTKGPPFLTARSTGYVVWHPS-PTWETPLKSTRPQNEDPPPSSFPGPPSTLVAVTPETPACVPGPIGKVTISNVTSTSFSLKWSADLHLSPAFCLTLVSPRGPAKTMETQHNNVTLSGLELGTLYLVEIMAKVCGKEGARTQLKVRTTAHKLTGKVRIPSMQYSESFRNASSREHQEFVQMFFRTVRDSLPATLRQHMDEGRIQVDIINITNGSVVVEFNLLMTADLDVREVSAGFLSAFQNTSMLEVVRGKTIIQDYNECDMREDDCAPGT-CTNTFGSFTCSCDGERPNSQVEYSGRSCD-------AQTPGSEWLPT-------PVPDASSTPQDLPLRLNLTDAVRVSCEIEMVVIAIQKRFLQQEAIPEASLYLGEPSCNVSRSNSTHVFLVTGWGQCGTLVQSNMTTTVVKTTLRNDLSPEGVIHHLQILSPIHCAFQNDLLTSSGYTPQWGVYTVIEDLHGTGNFVTEMQLFIGDSPIPQNYSVSASDEIKIEVELHRQKSNLKVVLTECWATPSSNAKDPVTFGFINNSCPVPNTYTSVIQNGNSSKAQFKLRIFSFINNSIVYLHCKLRVCMENPRNSCRINCNDFRLLRSSE--AIHQMT--WGPLHRSEGAQACTKPGLGTGYIILIAAAVLVVVAGAATLLILRYQRVKQKYNLRIQSDDFSYQVFSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DID3-1", "uniprot_id": "UROL1_MOUSE", "id": "Q5DID3-1", "name": "Uromodulin-like 1", "aln": "-----MMSRTVRLVLLALACTVDLSQASGFTENGLSLLSYQLCSYPVTRSVQKLQAVQTSHTAYVYCGGWIPWKKCPKTVYRTQYLAMDVPESRNVTDCCAGFEQLGLYCVLSLNRSREFASRPGVCPTAEAE----PLSPSCSLDTDCSGLQKCCSWPGGRHCVSPTPTGTEKSMVS-WYNVTVLVKVGFEDLQREDPGLRNHTRLLYSLVTSALQPLNPAVHYLTSTGGKDTFTTVSWLLMGFPRLMTVANVSVMLDDMVNRVYEVVSIQVQDVNECLHSELQACSVREQCRNLEGSYQCVS---------------------SQRLNHTDEDCPPIRDFVALNVTSSSFHVSWSLNSTQNYNFHIQVYK-GKEILRSAWTRGHTMAVSDLEAGVLYRVRTSYLGCGAN-VSATLVVKTDAQVFQVTIRIMDRNLTEQILDCSSGEFWNFSRQLFHEVQNSFPQAISDLYRQGRLRMQIVSLQAGSLVVTLRLTLQDPDFSVGVHTLTPMLPVLSVSNVFQVDQQRTFVQDWDECAHSSEHDCHPSARCINLEGSYTCQCLT-ARDASPSRAGRVCEGDMVIPTGDELSVTT-KVTVPAASTGITTFGPETLTESLSSKHPRSTPARSQTWTPVPPSVRDGGSIVRQDRNSTGQGQTHGTHQGTTDAPLHTTRESQELITKDPPFLTATTTGYVVWHSS-PTWKTPPNSTRLQNEDPRSSSFPGPPSAPTDVTPESPACVPGPIGKVTVSNVTSTSFSLEWPADIRLSPAFHLTLVSPRGPAMTMETQNNNVTLSGLEWGTLYLVEIVAKVCGKEGARTQLKVRTVAQKLAGNVRITSMQYSESFLNTSSREHREFVELFFRTVRDSLPATLRQHMDAGRIRVDIINITNGSIVVEFNLLMTADLDVREVSAGFLNALQNTSMLEVVRGKTFMQDYNECDMKEDDCAPGT-CRNTFGSFTCSCDEGGPDSQVEYSGRSCDGDPSGNMTQTPGSEWSPTPAGTRGVPVPIASSTAQDLPLRLNLMDAVSVSCEIETVIITIQKRFLQQAAIPEASLYLGEPSCNVSRSNSTHVFLVAGWGECGTILQSNMTTTVVTTTLRNNLSPEGVIHHPQFLSPIHCAFQNDVLTSSGYTPQWGVYTVIEDLHGTGNFVTEMQLYIGDSPIPQNYSVSASDEIKIEVGLHRQKSSLKVVLTECWATPSSNAKDPVTFSFINNSCPVPNTYTSVIQNGHSSKAQFKLRIFSFINNSIVYLHCKLRVCMENPRNSCRISCNDFRSLRSSE--ALHQMT--WGPLHRTEGAQACTKPVLGTGYIILLAAAALLVVAGATTLLILRYQRVRQKYNLRIQTDDFSYQVFSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5DID0-1", "uniprot_id": "UROL1_HUMAN", "id": "Q5DID0-1", "name": "Uromodulin-like 1", "aln": "------MLRTSGLALLALVSAVGPSQASGFTEKGLSLLGYQLCSHRVTHTVQKVEAVQTSYTSYVSCGGWIPWRRCPKMVYRTQYLVVEVPESRNVTDCCEGYEQLGLYCVLPLNQSGQFTSRPGACPAEGPE----PSTSPCSLDIDCPGLEKCCPWSGGRYCMAPAPQAPERDPVGSWYNVTILVKMDFKELQQVDPRLLNHMRLLHSLVTSALQPMASTVHHLHSAPG-NASTTVSRLLLGLPRPLPVADVSTLLGDIAKRVYEVISVQVQDVNECFYEELNACSGRELCANLEGSYWCVCHQEAPATS-------------PRKLNLEWEDCPPVSDYVVLNVTSDSFQVSWRLNSTQNHTFHVRVYR-GMELLRSARTQSQALAVAGLEAGVLYRVKTSYQGCGAD-VSTTLTIKTNAQVFEVTIKIVNHNLTEKLLNRSSVEYQDFSRQLLHEVESSFPPVVSDLYRSGKLRMQIVSLQAGSVVVRLKLTVQDPGFPMGISTLAPILQPLLASTVFQIDRQGTRVQDWDECVDSAEHDCSPAAWCINLEGSYTCQCRT-TRDATPSRAGRACEGDLVSPMGGGLSAAT-GVTVPGLGTGTAALGLENFTLSPSPGYPQGTPAAGQAWTPEPSPRRGGSNVVGYDRNNTGKG---------VEQELQGNSIMEPPSWPSP---TEDPTGHFLWHATRSTRETLLNPTWLRNEDSGPSGSVDLPLTSTLTALKTPACVPVSIGRIMVSNVTSTGFHLAWEADLAMDSTFQLTLTSMWSPAVVLETWNTSVTLSGLEPGVLHLVEIMAKACGKEGARAHLKVRTAARKLIGKVRIKNVRYSESFRNASSQEYRDFLELFFRMVRGSLPATMCQHMDAGGVRMEVVSVTNGSIVVEFHLLIIADVDVQEVSAAFLTAFQTVPLLEVIRGDTFIQDYDECERKEDDCVPGTSCRNTLGSFTCSCEGGAPDFPVEYSERPCEGDSPGNETWATSPERPLTTAGTKAAFVQGTSPTPQGLPQRLNLTGAVRVLCEIEKVVVAIQKRFLQQESIPESSLYLSHPSCNVSHSNGTHVLLEAGWSECGTLMQSNMTNTVVRTTLRNDLSQEGIIHHLKILSPIYCAFQNDLLTSSGFTLEWGVYTIIEDLHGAGNFVTEMQLFIGDSPIPQNYSVSASDDVRIEVGLYRQKSNLKVVLTECWATPSSNARDPITFSFINNSCPVPNTYTNVIENGNSNKAQFKLRIFSFINDSIVYLHCKLRVCMESPGATCKINCNNFRLLQNSETSATHQMS--WGPLIRSEGEPPHAEAGLGAGYVVLIVVAIFVLVAGTATLLIVRYQRMNGRYNFKIQSNNFSYQVFYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GKF5-1", "uniprot_id": "A0AC58GKF5_DANRE", "id": "A0AC58GKF5-1", "name": "", "aln": "MFARVFWIKADSRETMGVWKDVE-ERSRCQRGYEQTLSGYHLCNMNELVSMTRVVSYPSPYTQRRACGGWLPWNMCDVTVYKTAYQTEVYYISRQVKTCCHGYEQVGSYCALPLNRSAEFTSKPGLCPSARATGNHSDSGTVCNWDTDCPQWQKCCQTEN-NSSISRCLEPVPAANRTWCFNVTITVRTTYELLA-IDKGLLNHTRLLHSVVTGALGNAEFSVHHVWSWSA-GLFATSSSLLVCASKDFSIEDISAKLYQLGN-IEEVTNVVVQVPSVIAEPFINTTTPSLITRSASGTNMFIGEPSSTVTSGPFWTSSHSYNPTSSPPSSTCDGVPEITRILSYDVTASSFHVEWITKTQTGVTFLLLLQKNGTAVHAWNDVTSFNWTFTDLNPAALYTVRVTPSACGIQGNPVEIKVRTDGQLLGATVRLTNVMYTEALSDPNSAAYKEFCDSFINETRLSLPPEILELLLSRKLILQITSISPGSIIVNFTIIFQPGSNLDIRNISNALMNSLQNSTKYVIDKNSIHISDLNECLL-AEADCSRWAHCINTEGSYSCDCWSGYTDLNPRRPGRSCA--------------------ASSNATASTVHPATNYTELSSAAITGNPSVSR---------------------------------------------------------------------------------------------------------------------------TNVQSNLTTTTMSSASSTYANRLIQAISPATTLNITCHSVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CITVECSPWLIKVDIRRDYLKANNISETSLYLGNPECGPAGFDDSYLWLITAWDKCGTTPEHNNTHNSFSVTLFNNVSSSQTTTHLKVP--VTCTYPSSVIISMGYAPAGYFEMINDPVNGWGSFEVLMRLLNGTHPLPENYTISQNENIFVEVGVNTTISQIKTVINKCWATSSSDSSQPSNYVFLDNGCPVPEKHTNVLQNGNGTVSLVAVQIFSVVNLDFVFLHCEIQICIAFQDSSCIPACDRLLSARSSKLFGLTRSVGPLNRLHTTTFQSNTSNTVQAVGFVLLGVGVFLLSLTVIAGLLYQKRKIGNYNFHVRPQPENFTYNVFNT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.: * :: :* .*:**. :: :: : :.:* ****:**. * **:* * **:*. ** *:**:* **.*. *:* :*:*:** **: . . *. * **. :*** . . .:: :***: *: :: * * * ** ***:*:**.** :**:: * . . :* * **: .: :.: ::*. * :: : : ** .: ** . ::: : . .*: : . . .. * : : :**:.**:*.* :: . .* : : : * : . . :...*:...** *:.: .* : .. : ::*:.::: .*::: : ** : : .* : :*. .:::*.. *:* : :: . :* :**.*:..**::* : : .* . .:: * *. : :*:: :.* :** :* ** * *** ****:*:* : * .* *.** * .. . ::. . . *. ..*: .: *.. * : ..:: * . .** .:: .*: .: * *. : : *:: :*: *.*:****..*.*. : :.::: * :.*.:*** : * * . . .** *::* . * :. : *:: ..:: * *:: . : : ::* *.* . *:* * *:*:**::* .::: :** : *.:*.*:.:****.**:: :* .: *::*.****:.:*.*::**:.. : . ::***.:* .:*:***::::*: :* *: : :.*: . : . * : ::. ..*:::* . . :: :: : ** : : . .::.: *.::*:*:** ", "identical_positions": 221, "similar_positions": 341, "identity": "16.25%" }, { "cls_id": "homologset.agr.MGI:1929813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CFG6-1", "uniprot_id": "CA2D2_RAT", "id": "Q8CFG6-1", "name": "Voltage-dependent calcium channel subunit alpha-2/delta-2", "aln": "------------MAVPARTCGASWPGPVRTARPWPGRGPRPCPDPRGPASGPARPLLLLLPPLLLLPLLTAPGASAYSFPQQHTMQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFDVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIMYYDAKADAELDDP-----------ESEDMERGSKTSALRLDFIEEPNFKN-KVNYSYTAVQIPTDIYKGSTVILNELNWTEALENVFIENRRQDPTLLWQVFGSATGVTRYYPATPWRAPKK----IDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVS-CFTH-LVQANVRNKKVFKEAVQGMV-AKGTTGYKAGFEYAFDQLQN-SNITR----ANCNKMIMMFTDGGEDRVQDVFEKYNWPN-------RTVRVFTFSVGQHNYDVTPLQWMACTNKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKDAKQVQWTNVYEDALG--------------------------------------------------------LGLVVTGTLPVFNLT----QDGPGDKKNQ-----------LILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQITN-------FREPVTLDFLDAELED--------------ENKEEIRRSMIDGDKGHKQIRTLVKSLDERYIDEVIRNYTWVPIRSTNYSLGLVLPP-YSTYYLQAN---------LSDQILQVKLPISKLKDFEFLLPSSFESE------------------GHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQ-------------------------------CNNFLLHNLILDTGITQQLVERVWRDQ-----------------------DLNTYSLLAVFAATDGGITRVFPNKA---------AEDWTENPEPFNASFYRRSLDNRGYIFKPPHQDSLLR--PLELENDTVGVLVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQD-QPQKQCGPSSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTIADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADP------------------------------AEAEGSPETRESSCVMKQTQYYFGSVNASYNAIIDCG--------------------------------NCSRLFHAQRLTNTNLLFVVAEKPLCSQCEVGRLLQKETHCP----ADGPEQCELVQRPRYRTGPHICFDYNATED-TSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQIHSFTPSRRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PHS9-1", "uniprot_id": "CA2D2_MOUSE", "id": "Q6PHS9-1", "name": "Voltage-dependent calcium channel subunit alpha-2/delta-2", "aln": "------------MAVPARTCGASWPGPVRTARPWPGRGPRPCPDPRGPASGPARPLLLLLPPLLLLPLLTAPGASAYSFPQQHTMQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIMYYDAKADAELDDP-----------ESEDMERGSKTSALRLDFIEDPNFKN-KVNYSYTAVQIPTDIYKGSTVILNELNWTEALENVFIENRRQDPTLLWQVFGSATGVTRYYPATPWRAPKK----IDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVS-CFTH-LVQANVRNKKVFKEAVQGMV-AKGTTGYKAGFEYAFDQLQN-SNITR----ANCNKMIMMFTDGGEDRVQDVFEKYNWPN-------RTVRVFTFSVGQHNYDVTPLQWMACTNKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKDAKQVQWTNVYEDALG--------------------------------------------------------LGLVVTGTLPVFNLT----QDGPGEKKNQ-----------LILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTN-------FREPVTLDFLDAELED--------------ENKEEIRRSMIDGDKGHKQIRTLVKSLDERYIDEVIRNYTWVPIRSTNYSLGLVLPP-YSTYYLQAN---------LSDQILQVKLPISKLKDFEFLLPSSFESE------------------GHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQ-------------------------------CNNFLLHNLILDTGITQQLVERVWRDQ-----------------------DLNTYSLLAVFAATDGGITRVFPNKA---------AEDWTENPEPFNASFYRRSLDNHGYIFKPPHQDSLLR--PLELENDTVGVLVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQD-QPQK-CGPSSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTIADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADP------------------------------AEAEGSPETRESSCVMKQTQYYFGSVNASYNAIIDCG--------------------------------NCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHS------DGPEQCELVQRPRYRRGPHICFDYNATED-TSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVHSFAASRHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY47-1", "uniprot_id": "CA2D2_HUMAN", "id": "Q9NY47-1", "name": "Voltage-dependent calcium channel subunit alpha-2/delta-2", "aln": "------------MAVPARTCGASRPGPARTARPWPGCGPHPGPGTRRPTSGPPRPLWLLLP---LLPLLAAPGASAYSFPQQHTMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIVYYDAKADAELDDP-----------ESEDVERGSKASTLRLDFIEDPNFKN-KVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGSATGVTRYYPATPWRAPKK----IDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVS-CFTH-LVQANVRNKKVFKEAVQGMV-AKGTTGYKAGFEYAFDQLQN-SNITR----ANCNKMIMMFTDGGEDRVQDVFEKYNWPN-------RTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALG--------------------------------------------------------LGLVVTGTLPVFNLT----QDGPGEKKNQ-----------LILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTN-------FREPVTLDFLDAELED--------------ENKEEIRRSMIDGNKGHKQIRTLVKSLDERYIDEVTRNYTWVPIRSTNYSLGLVLPP-YSTFYLQAN---------LSDQILQVKLPISKLKDFEFLLPSSFESE------------------GHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQ-------------------------------CNNFLLHNLILDTGITQQLVERVWRDQ-----------------------DLNTYSLLAVFAATDGGITRVFPNKA---------AEDWTENPEPFNASFYRRSLDNHGYVFKPPHQDALLR--PLELENDTVGILVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQD-QPQK-CGPNSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADP------------------------------AEAEGSPETRESSCVMKQTQYYFGSVNASYNAIIDCG--------------------------------NCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHS------DGPEQCELVQRPRYRRGPHICFDYNATED-TSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVLVHA-SRRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E7N5-1", "uniprot_id": "A0AB40E7N5_DANRE", "id": "A0AB40E7N5-1", "name": "", "aln": "------------MAMFAQSS---------------------------------SLFCLLSVQTVLLLSFSSPGTATLLFPQHYTMMHWAGRIEKELEKVLQLVTGGQQMRAIYNDKRNQFDVVRNTPKQLVEKVAGDIAKLLNRKRKALERLAREAEDIQREHSWQDAIKENDIQYYDAKADSDVMD------------DDDGENLLDNPNSLSLEFVDDPNFKN-KVNYSYTAVQIPTDIYKGSPTILNELNWTQSLERVFIENSREDPSLRWQVFGSTTGVTRYYPATKWKAPNK----IDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVIEMLDTLSDDDYVNVARFNEKAYAVVPCFTT-LVQANIKNKKIFKEAVMNMQ-AKGTTDYKTGFQFAFDQLLNDTSAPR----ANCNKMIMMFTDGGEDRAQDIFEKYNWPN-------RTVRVFTFSVGQHNYDVTPLQWIACFNKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGERAKQVQWTNVYQDALG--------------------------------------------------------LGLVITGTMPVFNLT----ADR-DTKQNQ-----------LMLGVMGVDIALNEIKELTPRYKLGANGYTFAIDPNGYVLLHPNLQPKIIN-------FREPVTLDFLDAELPD--------------RNKEEIRRQMIDGRGGQRKIKTLVKSVDERYIDESQRTYIWSPVEGTDYSLGLVLPS-YSENHIRAN---------LSDQILQVQYG-SDFKDFESLLPNTFESE------------------GHVFIAPREYCKDLELSNNNTEFLLNFIALMEKVTPDSKQ-------------------------------CDNFLLHNLILDTGIIKQLVDRVWKIN-----------------------DLNTYGFLAVFAATDGGITRVFPNKA---------AETWEEDSEPFNASYYRRSLDNKGYIFRAPYRTANDD--IMNPENDTIGILVSTAVDITMGSRNLKPAVVGVKLDLEAWTDKFKILASNHTDSNRLSSQTCGPTSGCEMDCEANSDDLLCYLIDDGGFLIMSNQKDHWYKIGMFFSEVDPTLFYALYNNSFYRRKQSFDYQSVCDPVPSSNTGAAPRGVFVPTIADMLNVAWLTSAAAWSLLQQMLYGFAYQSWFMTDE------------------------------VDAEG-FEYKETSCVTVQTQFYFSNISSSYNILQDCD--------------------------------NCSRLIHAKRINNTNLLFVVAERLSCNSCEIEKLSQVETEY------KETKACETIAAPRYRKGTTSCFDYSVLEN-TSDCGRGHSFRPSLYTLLLLQLLLLSAMAR---PSV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AUK1-1", "uniprot_id": "A0A8M3AUK1_DANRE", "id": "A0A8M3AUK1-1", "name": "", "aln": "------------MARWAHAC--------------------------------------LLLLLMVILGGSWTAVNALTFPQHYTIMHWARRIEQEIDRVLQHISGAQQLKGIYLEKKKHFSLVRNNPRDIVEKVATDIERLLAKKRKALERLASEAERLQKEHRWQDGIKEENIEYYNSKAEMDYDGE-----------DIDS------QMSLKLDFVYDPSFKN-QVNYSHTAVQIPTDIYKGAPVILNELNWTQALERVFIENSRDDPSLLWQAFGSATGVTRYYPAAPWRAPDK----IDLYDVRRRPWYIQGASSPKDMVILVDVSGSVSGLTLKLIKASVTEMLDTLSDDDYVNVARFNEKAEAVVPCFDH-LVQANVRNKKIFKEAVQQMQ-AKGTTDYKSGFHFAFNQLLNKTNVPR----ANCNKIIMLFTDGGEDRAQDIFEQYNWPN-------KTVRVFTFSVGQHNYDVTPLQWIACSNKGYYFEIRSICAIRINTQEYLDVLGRPMVLAGRIAKQVQWTNVYQDALG--------------------------------------------------------LGLVVTGTMPVFNLT----VNG--DSQNQ-----------LILGVMGVDVHLDELKRLTPQYKLGANGYIFAIDPNGYVLMHPNLQPREED-------LPEQVTLDFLDAEVED--------------SSKQEIRRQMIDGRSGDMTIKTLIKSMDERYIDDVTRMYTWTPINDTDYSLGLVLPP-YSEHYIQAD---------LSDVMLQLQYL-------QSLLPNSFESA------------------GHVFLAPRDYCRRLHISENNTQFLVDFLSLMVEISPESED-------------------------------CDQGLIHNLILDSGILWQLATRVWQNK-----------------------DLGTYGFLALFASTNGGVTRVYPNMA---------AESWDEDPEPLNSNFYRRSLDNKGYIFRAPTRTSMDD--LLISENGTVGILVTTAVEVAFGSKTMKPAVVGVKLDLEAWVDKFKILASNVSDSR-QAAHKCGPSRSCEMDCEVNSDDLLCYLIDDGGFLVMSNQRDHWKKVGLFFGEVDPYLMFALYNNSIYSRHQTFQYQSACEPTASSHTGAAHRGFYVPSIADFLSLAWWTSAAAWSILQQFLYGVMYSSWFTTAD------------------------------VWAESADSKGSSSCVTVYSQFYFTNTTNSFNVLQDCG--------------------------------NCSRLFHAKRIENTNLLFVVAETLPCSSCEIEKLLPVRTKS------QEENPCDVLNSARYRKGPDKCFDYNSEEN-TSQCGSAHSLHCPLPALLLVQLFLIYLILRS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP22-1", "uniprot_id": "Q8IP22_DROME", "id": "Q8IP22-1", "name": "", "aln": "MFGLCEKLMTHFAVILTAFS------------------------------FSQPLLLLLICGPHGGTFPSTSIHWAEASAADEAVGKWATQFGDELFALAQKITKSQEIKEKYKEYN--ARVELKNGTELIKSITKNVGRMLARKMDAVRCIQERAEYVNENFEFNLTYALQNFTYFSSKYSTFNGN---------SSEELEPNEAEFAWMYRNMELNPDTHFYNTPVDTEHSSVHVPSNIWDRSERVLKTIMWSEHLDEVFRQNYQSDPALSWQYFGSDTGILRHYPAAQWTDTRPNRDDADTYDCRKRSWYIETATCSKDIVILLDHSGSMTGFRHHVAKFTIRSILDTFSNNDFFTILRYSSEVNDIIPCFNGALVQATPENIEVFNQQIEQLDDPEGYANLTLAYETAFQLLRKYYDSRHCVTNSTCNQAIMLVTDGVAGNTTEVFQKYNWGNGENGTSQMDTRVFTYLLGKEVTKVREIQWMACLNRGYYSHVQTLDEVHEEVLKYVDVIATPLVLQ-NEQHPPTWTHAFT-------------------------------DKTYDPKTSNEKRPR----------------LMISVGVPAFDR----FYRHANSTNPRARL----------LGVAGTDVPVEDIDKLTLPYKLGVNGYSFVVSNNGYVLLHPDLRPIGTN----GKMNPNYNSIDFTEVEHLF----EDQSPREPGESILHIRNAMVRHEANEFKSISVKFHYDKMRRVSEEKQDYFFAPLPNTPFTLGIVMPSEYGKTWIKVG--EEVDKNKHMKINISDFFIGENWKVHPDWVYCKYHYL-----------------EGHEFKTPEAELREFLAKMQN-DWKWS----EQYAEDESDWDDKDDLNCG-----------RKTLG-DDAYYCNKELVNLLIFDAKVTNSSYGVWRFESDEER------------------QLIERFRADLRFVATMSGLTRWQFIFG--EVEVDTDREFGDYHTTAIDETWYKSAILQHHEDRAESFVYSVKY-YDDPMEDSEVKVTASHAIFPRDGGKEAPACVVGFQFSHARMWERFFNITAVDH-CN-----------HCLPICTDD--DVDCVVIDNNAYIVIG---QNINTTGKFFGEFHGDVMTAMVERGIFLSIEVYDYQEQCKEEPKAGSDGHGLLHPLR----------LLSLGWKYLVGRLFFEYQRIQWWADG----------------APFMEYTDEIEDEYVAVGDGGKSSASKPKDDSDDENAMFDEPEPDPIYKACDKRSTLYALQPSALV----------GINDFVEAPSTRPFLVKKIPNSNLVLVVVNVLMP-SRSVRLTTEPQRMEY----DKEFPCYKLNMSFYERRRIEECYTVHEDEELYTYCGNASRLVLTLQLMPLTIILVFYLTHSFMR------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K866-1", "uniprot_id": "A0A0B4K866_DROME", "id": "A0A0B4K866-1", "name": "", "aln": "---------MAWSRLLAWWR------------------------------LCLGLLSVLVC-----LAPCVNLQPAEN-INYNLVHSWADKLGMELFHLGDFITRRKEVQESFKD----AKVVSRNGASIVDSMAKEIEMMMDLKVSAVRRIMDTAENTALSHQN--DMADKMFSYYSAKEMLEPGDPVPPIPTPAPDMDKDIGEPLIYVQPKVVVLEPRPEFHNTPVNFSVSSVHVPVNVFDRAPDVIKAIQWSENLDQIFRDNYKNDPTLSWQFFGSSTGFMRQFPASKWRKDVP----VDLYDCRLRSWYMEAATSPKDIVILMDGSGSMLGQRLDIAKHVVNTILDTLGTNDFVNIFTFDKEVSPVVPCFEDTLIQANLGNIRELKEGIELFR-PKSIANYTAALTKAFELL---EETKLSSRGAQCNQAIMIIGDGAPENNREVFELHNWRD----PPYKPVRVFTYLIGKEVANWDDIRWMACENQGYYVHLSDTAEVREMVLNYIPVMARPLVLG-RHDHPVIWSQVYADIEDTKLSDYLWDINQCEYQKADVLEYWQVHDRMLEPSEMHRRKYRRMKETWNQPVDSNVYQFMTTVSMPIYDRRENALINLTTDINPAAKINLQVTRIANILGVAGTDVPINEIKKLLSPFTLGVNGYAFIVTNNGYVLFHPDFRPIFQG----YILKPAYNSVDMIEVELLD----DDRPARDFNPVLMTIRDSIIN-QSTGSKWMLVKNHFDEMKRVARVKRQYYWTAIKKTPFTLVISYPEQYGVSHMDIRADQEIHRISIKGTNLRSVFSGKRWKIHPDWLFCKHS--------------------NRTFKTPEIELLYFLERMSEPGWRWPGSRSAMPPEHAAAMFSNNSSTGR-----------YPSINEKESYYCDRQLMQALVFDARVTGWFSNNTSFNSKDDKGTSASSPIAVLMGLLPRNEFKQRFGVTVAFLATHSGLTRWHEFHSNAAEESGVGETFSQNNTRAIDEIWYKRAVDQHFVR-EESFVYSVP--FDAGESNSEILVTASHAVFHNEGGKTAPAAVVGFQFQHSALYKLFHNITGN--------------------ACAVD--DKDCYILDNNGYVIIS---TRVHETGRFFGEVNGAIMKRLLEENVYRQVTVYDYQAVCFESKNDNNASSMLLSPLFH---------LLRVGKWLLHTALWYIVQLLQWAPGVS------------SHYADMYGDSNDTEPPPPEPHPDHHARNGNGHGKKDDDHWLRYLTLHRTRLKPCDMKRDLYTLFNEKDN----------VVYNMTAHACERPFVVLPIPFSNLILLVIDQLCPRDGSVVLTVNPQPIDYHLSVNDSLACYKQAREFN-RMRPHSCISRHANESGIKLCGKACSVYANLGLLLLCHILSRWL------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2J9Z3-1", "uniprot_id": "X2J9Z3_DROME", "id": "X2J9Z3-1", "name": "", "aln": "------------MESKHWSC------------------------------FVAIVLGVLIFK----MHIFVAFADQDEDIPHNEVRNWALKFGVDLWEFGRQFTKMNEIKSRFKDND--IEVKRKDGIILLRELAAEVKNFMDFKRNAVMRLMDSAEQAALSELEGQGQAESPMGGQQHYDAR--------------RINEYNADGKLADGARHMDIRFMRRFERLPVNLSLSSILVPHGVDLDEPDVKSALQWSGHLDPLFQNNLEQDPALSWQYFGSSTGFLRRFPGTAWPPEGS-KGSKLIHDFRTHNWFVQAASSPKDIMILLDASSSMTEKSFDLGMATAFNILDTLGEDDFVNLITFSEVVKTPVPCFKDRMVRATPDNIQEIKSAVKAIK-LQDTANFTAGLEYAFSLL---HKYNQSGAGSQCNQAIMLITESTSESHKDVIKQYNWPH-------MPVRIFTYLIGSDSGSRSNLHDMACSNKGFFVQINDYDEARRKVIDYALVMARPMIMY-QADHPVHWSPVFVAG------------------------------KSGGLGRDSEYQRR----------------LVTTVSTPVFDR-----RNHSVRVAN-------------LLGVVGTDVPIEEIRKVIPQHKLGPNGYSFIVDNNGRVLYHPDLRPLGDANQYIDQLKPKYASVDITELELPETEFGNNNEPIEINKNLLNEMRGDMIKPKEGETEFTVMNHYDDSKRVSTRTHRYFYGPIEDTPFTLAIVLPEKYGSHEFVSQ-----QEIRHSRNNVTEYFKGDNWRVHPDWVYCEYNSVSDLEKERESSGEYSSRDQEPSFGSPEEQVLHFLSRAGRPGWKWMSVRPKSPQPHHNMHSGSNGGNAPGSSHFGSQHQSSQGSRKAEPYFCDRALLQSLVRDAMVTDGLDRNTTGSSSGKEDKHPIATLMAILK----RQGYQKFVVATSFVATRSGLLRWIDHVK--RPEDTPEPHFSEDNVRAMDTSWYKRAIDQHSVE-PDSFVYSVPFGSGYAIKSNATLVTASHAIFVEHRGHKAAAGVVGLQFQHDSLAKHFINITSACTGMT-----------GCKRTCASD--NLDCYVLDNSGFVIIS---EEMEHTGKFFGQIDGTIMDSLVQDRIYKRVTVNDYQGVCSDADNPYTAAGGILKPNRLGSWFFNHLLALSAAWLSLMPASLRAWPQEEYTYDNEDVVFVDNNYSDEYEFGNENEYNMQVDQEMDEFFTTADVEYTTPPPRQHKPHVGPRFSPDPHNARRCDLRTDLYMLQPERLNQGGQNNPLKGKLTNCHVSGCERPFSVQKIPHSNLILLVVDTLCP-CGSKQLDIEPLEEAG---VIGACSTRRQGQEQESRRRPKKCINYHPEEIEIQQCGRGSTLLHMSGSVIVAHLLMVTVTFVLANA-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ** :: :: . . :::: : : : . :: .:: :: :: * .*: : ** . : . : : : * . *: . ::: :* .: : . : *: *: :* :* ..**:* ** *** **. * :*.: * :* * : *::: *:..**::*::* *.*: .: :***:. :*:..: :.. . ** :::*. * . ::. : : :. :. . . **. * . : **: **:. :. :::: :** . .*:**: :*.. . :: :** *:*:: .: : . .* *:. *::: . : *: .: :: : * :: *** * *: :::: .: ..** *** * : ** ** **:::* ::*: : * : : . : . : : : * : .: * ::* : * *. : : : . * :*. : . : *:. *:: *: *: : . : * :* .*: * . .:: :*: :: :: . : ... : .: *: : . ***.::. . * ::. * : : * ::*:..::::. . * **.:.. :: : : .: :** * . . : .: . *. . * : . : :**:::* : . * * * ** . . : :: ", "identical_positions": 127, "similar_positions": 275, "identity": "8.74%" }, { "cls_id": "homologset.agr.MGI:1929864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641W2-1", "uniprot_id": "MYG1_RAT", "id": "Q641W2-1", "name": "MYG1 exonuclease", "aln": "MGRGFLRGVLTLLPLRS--------VLQVQHCMLVSEPDLPPKRP-RNNLMAP-PRIGTHNGTFHCDEALACALLRLLPEYRNAEIVRTRDPEKLAL-CDIVVDVGGEYNPQRHRYDHHQRTFTETMSSL---CPGKPWQTKLSSAGLVYLHFGHKLLAQLLGTSE----EDSVVDTIYDKMYENFVEEVDAVDNGISQW-----AEGEPRY-ALTTTLSARVSRLNPTWNQPDQDT--EAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPTVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATLAQRTAPVPLANAVVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK81-1", "uniprot_id": "MYG1_MOUSE", "id": "Q9JK81-1", "name": "MYG1 exonuclease", "aln": "MGRRFLRGILT-LPLRS--------VLQAQHRMLGSEQDPPAKRP-RNNLMAP-PRIGTHNGTFHCDEALACALLRLLPEYANAEIVRTRDPEKLAS-CDIVVDVGGEYNPQSHRYDHHQRTFTETMSSL---CPGKPWQTKLSSAGLVYLHFGRKLLAQLLGTSE----EDSVVDTIYDKMYENFVEEVDAVDNGISQW-----AEGEPRY-AMTTTLSARVARLNPTWNQPNQDT--EAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPKVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATLAQRPAPVPLANAVVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB07-1", "uniprot_id": "MYG1_HUMAN", "id": "Q9HB07-1", "name": "MYG1 exonuclease", "aln": "MGHRFLRGLLTLLLPPP--------PLYTRHRMLGPESVPPPKRS-RSKLMAP-PRIGTHNGTFHCDEALACALLRLLPEYRDAEIVRTRDPEKLAS-CDIVVDVGGEYDPRRHRYDHHQRSFTETMSSL---SPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSE----EDSMVGTLYDKMYENFVEEVDAVDNGISQW-----AEGEPRY-ALTTTLSARVARLNPTWNHPDQDT--EAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFIGGHRTREGALSMARATLAQRSYLPQIS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140LG01-1", "uniprot_id": "A0A140LG01_DANRE", "id": "A0A140LG01-1", "name": "", "aln": "MTHAHTASPVRLAALQRRQSSSRGSSSSRNHQMRVCSRLLSSVLINKHHLMKMKMKIGTHNGTFHCDEVLACFLLRQLPEYKDAEIVRSRDASVLAE-CDVVVDVGGEYDHSRQRYDHHQRAFAESFHSV---CAQKPWVTKLSSAGLVYVHYGRRVLQQLTHLQE----DEPQLEVLYDKMYEGFVEEVDAVDNGISQ------SDGEQRY-TISSTISSRVSYLNPQWNSKEQDT--EEGFRKALALVGSEFQDRLLYFTNAWLPARDVVLQAIKSRHQVDVSGQVLLLQQGGCPWKEHLFALEKELQLQELIKFVLYCDQNGHWRVQCVPAGPNTFQNRLSLLEEWRGLRDDALSELSGIPECIFVHAGGFIGGNKTQSGALEMARRTLQTAPTH---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40093-1", "uniprot_id": "YEY6_YEAST", "id": "P40093-1", "name": "MYG1 protein YER156C", "aln": "--------------------------------------MNSVKRVKLNSKMSK--QICTHSGSFHADESLAVYMLRLLPEFKDAKLVRSRNPKDWEA-SDILVDVGAQYDG-VKFFDHHQRGFFETFN--------EKYKTKLSSAGLIFKHYGRDIIKTILNNKV----SSSDLDLLYDKVYKQFVEALDANDNGISKYTIPKDSNLEPNFRDNAISIPGIISGMNPNWNEDTSDESFDRCFARASEFIGGVFVTLVRGYGQSWLPAKALVAQAIDERMDVDKSGKIIVLPQ-FCPWKEHLYELEREKNIEKQIEFVLFTDSSGAWRVSTVPINSTSFQFRRGLPEPLRGLRDEELSTKSGVPGCIFIHAAGFIGGAKSKEAVYELAKMSLA--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8INP9-1", "uniprot_id": "Q8INP9_DROME", "id": "Q8INP9-1", "name": "", "aln": "-----------------------------MFRLLPRFPGKLSIMTGVTPPKRSPLWIGTHSGTFHCDELVACFMLKQLDEYKNAEIFRSRDNKALKEKCDIIVDVGGVYDHAKKLYDHHQITFKETFSSVRPDVSEDYNVVRLSSAGLVYCHYGERVIQSILQREKGIKLSPENLQTAFIQIYRNFINELDAIDNGVPMF-----EGVEPIY-KISTHLSARIAKLNPSWQETGVDI--EDRFRQAMDTAGREFVDNVVEVSCSWIPARDHVREALKNAKNVHPTGEILVLKN-FCPWKSHLFDLEKEYKVEGVPKLVVFN-SGNSWRVAGVPVTPGSYLGRKFLPTPWRGLMDDELCDKASIKDLEFIHHTGFIGGAKTEEAAMLLAKKSTEWTEEQ---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **.*:**.** :* :*: * *: :*::.*:*: . .*::****. *: : :**** * *:: . .:******:: *:*. :: : . . : : ::*. *:: :** ***:. * : : :.. :: :** *: * : * :* * : :*:**: * :*: . .*. :*::: * : ****.**: ** . :*:: . . **: ** . :: * * *** *. * :.: *:* ***** ::.... :*: : ", "identical_positions": 86, "similar_positions": 96, "identity": "21.13%" }, { "cls_id": "homologset.agr.MGI:1929865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80Z29-1", "uniprot_id": "NAMPT_RAT", "id": "Q80Z29-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNAAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKVRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVSENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENVSFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLSLHRTPAGTFVTLEEGKGDLEEYGHDLLHTVFKNGKVTKSYSFDEVRKNAQLNMEQDVAPH-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KQ4-1", "uniprot_id": "NAMPT_MOUSE", "id": "Q99KQ4-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNAAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKVRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENVSFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGHDLLHTVFKNGKVTKSYSFDEVRKNAQLNIEQDVAPH-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43490-1", "uniprot_id": "NAMPT_HUMAN", "id": "P43490-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAHH-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AKJ6-1", "uniprot_id": "A0A8M3AKJ6_DANRE", "id": "A0A8M3AKJ6-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "MNYKQDNLARNNELPMDFCQNQESNMMTSNNTRRLFQRFSKYQGLAVVLDEEKDALFRASPAAFKVSKTASENNQISQVESVSPKDTFSGNDGVSVVVFLHESDGVSERFLCSETDTSFPTNRVSVMDTFSEIDSFSQIEGVAPVDTFSETDDVSPTVGVPPMDTFYETEAVSQIDGVPSTHTV--SETDTVSQIDRVPILDTFSEIDSVTHHNQYPPNTSKMYSYFEYRKKKADPTNTRRLIQRFSEYQGLAFVLDEEEDALFRASPAFKVSKTASETNQISQIESVSPKDTFSENDGVS----------------------------------VVEGVAPVDTFSEIDDVSSTVGVPPMDTCFETDTVSQIDRVPIMDTFSEIDSVTHYNKHPPNNTSRMYSECHKK-ADPTNTRRLVQRYSKYQGLAVVLDEEEDAIFRASPAFKVSKTASETNPISQIESVSAKETFSEIDAVSQIDRVPVLDTFSETDDVSQASSASEDSGRHKEDADFNILLATDSYKVTHYNQYPPNTSKMYSYFECREKKANPNKPRKIRYDTTVFYGLQYVLHKYFKGQVVTLEKIQEAKEVYREHFHDDMFNEKGWNYILEKYNGHLPIEIKAVPEGSVIPRGNVLFTVENTDDECYWLTNWIETILLQIWYPITVATNSREQKKILAKYLMETSGSLDGLEYKLHDFGYRGVSSQETAGIGGSAHLVNFKGTDTMAGIRLIKKYYGTKEPVAGFSVPAAEHSTITAWGKDHEKDAFEHIVRMFPSVPVSVVSDSYDIYNACEKIWGEELRSLVEMRSADAPLVVRPDSGDPLETVLRVLEILGEKFPPLENSKGYKVLPPYIRVIQGDGIDIDSLQDILEGIKKHGWSIENIGFGSGGALLQKLNRDMLSCCFKCSYAVTNGVPINVFKDPIADPTKKSKKGRLSLHRTPSGSLVTLEEGSGSLGEYGEDLLQTVFRNGKIIKTYTFNEVRENAELKESELCPSEQFPSSPSSPHCSQTRAHTQHAETGT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PR57-1", "uniprot_id": "A0A8M9PR57_DANRE", "id": "A0A8M9PR57-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTFSET----------------EADTVSQIDRVSIMDTFSEIDSVTHYNKHPPN-TSRMYSECHKK-ADPTNTRRLVQRYSKYQGLAVVLDEEEDAIFRASPAFKVSKTASETNQISQIESVSVKDTFSEIDAVSQIDRVPVLDTFSETDGVSQASSASEDSGRHKEDADCNILLATDSYKVTHYNQYPPNTSKMY--FECREKKANPNKPRKIRYDTTVFYGLQYVLHKYFKGLVVTLEKIQDAKEVYREHFHDDMFNEKGWNYILEKYNIHLPTEIKAVPEGSVIPRGNVLFTVENTDDECYWLTNWIETILLHIWYPITVATNSREQKKILAKYLMETSGSLDGLEYKLHDFGYRAVSSQETAGIGGSAHLVNFKGTDTMAGIRLIKKYYGTKEPVAGFSVPAAEHSTITAWGKDHEKDAFEHIVRMFPSVPVSVVSDSYDIYNASEKIWGEELRSLVEMRSADAPLVVRPDSGDPLETVLRVLEILGEMFPPLENSKGYKVLPPYIRVIQGDGIDIDSLQDILEGIKKHGWSIENISFGSGGALLQKLNRDMLSCCFKCSYAVTNGVPINVFKDPIADPTKKSKKGRLSLHRTPSDGLVTLEEGSGSLGEYGEDLLQTVFRNAKIIKTYTFDEVRENAELKESELCPSEQLPSSPSSPHCSQTRAHTQHAETGT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q3K2-1", "uniprot_id": "A0A8M9Q3K2_DANRE", "id": "A0A8M9Q3K2-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "MNYKRDNLARNNELPMDFCQNQESNMMTNNNTRRLFQRFSKYQGLAVVLDEEEDALFRASPAAFKVSKTASENNQISQVESVSPKDTFSGNDGVSVVVFLHESDGVSETFLCSETDTSSPTNRVSVMDTFSEIDSVSQIEGVAPVDTFSETDDVSPTDGVPPMDTFYETEAVSQIDGVPSTDTVSETEADTVSQIDRVPIMDTFSEIDSVTHHNQYPPSTSKMYSYFEYRRKKADPTNTRRLIQRFSEYQGLAVLLDEEEDDIFRASPAFKVSKTASETNQISQIESVSPKDTFSENDGVSQGDGVPSTDTVSETDAVSQIDRVPVMDTFSEIVSQIEGVAPVDTVSETDAVSQIEGVAPVDTVSEADTVSQIDRVPIMDTFSEIDSVTHYNQYPPS-TSKMYSECHKKKADPTNTRRLVQRFSKYQGLAVVLDEEEDAIFRASPAFKVSKTASETNQIYQIESVSSKDSFSEINAVSQIDRVPVLDTFSETDDVSQASSDSEDSGKHKEDADFNILLATDSYKVTHYNQYPPNTSKMYSYFECREKKANPNKPRKIRYDTTVFYGLQYVLHKYFKGQVVTLEKIQEAKEVYREHFHDDMFNEKGWNYILEKYNGHLPIEIKAVPEGSVIPRGNVLFTVENTDDECYWLTNWIETILLQIWYPITVATNSREQKKILAKYLMETSGSLDGLEYKLHDFGYRGVSSQETAGIGGSAHLVNFKGTDTMAGIRLIKKYYGTKEPVAGFSVPAAEHSTITAWGKDHEKDAFEHIVRMFPSVPVSVVSDSYDIYNACEKIWGEELRSLVEMRSADAPLVVRPDSGDPLETVLRVLEILGEKFPPLENSKGYKVLPPYIRVIQGDGIDIESLQDILEGIKKHGWSIENIGFGSGGSLLQKLNRDMLSCCFKCSYAVTNGVPINVFKDPIADPTKKSKKGRLSLHRTPSGSLVTLEEGSGSLGEYGEDLLQTVFRNGKIIKTYTFDEVRENAELKESELCPSEQLPSSPSSPHCSQTRAHTQHAETGT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F8T6-1", "uniprot_id": "E7F8T6_DANRE", "id": "E7F8T6-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKHREAADFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTDSTKPRKVKYDKTVFYGLQYILHKYLKGQVITPEKIQEAKEVYREHFQDDVFNEKGWNYILEKYNGHLPIEIKAVPEGSVIPRGNVLFTVENTDPECYWLTNWVETCLVQIWYPITVATNSREQKKILAKYLMETSGSLEGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIGVIKKYYGTKDPVPGFSVPAAEHSTITAWGKDHEKDAFEHIIKQFPSVPVSIVSDSYDIYNACEKIWGEDLRSLIEMRSADAPLVVRPDSGNPLDTVLKVLEILGKKFPPEENSKGYKVLPPYIRVIQGDGVDINTLQEIVEGMKEHRWSIENIAFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLSLHRTPSGDFVTLEEGKGDLEEYGEDLLHTVFRNGKIVKTYTFDEVRDNAKLKESEVQDLLL------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RDZ8-1", "uniprot_id": "F1RDZ8_DANRE", "id": "F1RDZ8-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAAQDFNFLLATDSYKITHYKQYPPNINKVYSYFECRHKKG-------AQFSEVVFFGLQYLLKKYLTGPVITEEKIQEAKVFYQMHFKQAVFDEEGWRKVLEKYDGRLPIRIKAVPEGKIIPRGNVLFTVENTDADFFWLTNYIETMLVQMWYPITVATISREFKKILAKHLKATSGNLESLDLKLHDFGYRGVSSQESAALGGAAHLVNFCSTDTVAGLLMAQRYYG--CPMAGFSIPAAEHSTIISWGRSREKDAFECLLDQFPSGPVAVVSDSYDIFKACKHIWGDKLKERVMERSEDSALIIRPDSGDPAETLLEVIKILEECFGCSLNSVGYKVLPSYLRIIQGDGIDLNSINEILQKLSDEGWSAENVFFGCGSALLQKINRDTLNCAFKCSYVETCGKGMDVYKQPVTDPSKGSKRGRLSLRRNSDGFIETVERGAGKPEE---DMLVTVFENGTILQEYTLDEIRKAAQLREEDLSPSLHNREDGTTLDIHQKHIMNGVH----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:********:***:***** .*:* ****.** ::. .**:****:*:**:.* *:* ****:** .*: **:: :*:*.**. :****: :** .:****** :************** : :****::** *:: ******** *** ******:* ***.*:.*: ********.*****:*.:*.:****** .***:**: : ::*** *:.*:*:******** :**:.:****** :: *.* **::*******::*.::***:.*: : ** ::.*::*****:* :*:*.*:.** : * ** ***:**.*:*:*****:*::::::*:: :... ** **: **.*..****:.** *.*.*****. * * ::*:*:*::**.* **:*****:*.. . : *:*.* *. * *:* ***.*..: : *:::*:*. *:*. . ", "identical_positions": 253, "similar_positions": 145, "identity": "24.78%" }, { "cls_id": "homologset.agr.MGI:1929866", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZB1-1", "uniprot_id": "RGS20_MOUSE", "id": "Q9QZB1-1", "name": "Regulator of G protein signaling 20", "aln": "-------------------------------------------------------------------------------------------MRTANGG----------------PRARA--------------------------SPSASPADPG------------------------------------------------------------------------------------------------------LPEGSERTEMRMRQMCGGSE----TQGPAPSQQ---GGRGSNACCFCWCCCCT----------------------------------------------------------CSCLTVRNQE----DQRPQRASHEIRTD-IPACEESPTPTLEEVCAWAQS--FDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREAN--KSTIEEKAR---------------------------------IIYEDYISILSPKEVSLDSRVREVINRNMVDPSQ----------------------------------------------------------------------------------------------------------------------HIFDDAQLQIYTLMHRDSYPRFMNSTVYKDLLTSLAE-KTVEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L7Z3-1", "uniprot_id": "A0ABK0L7Z3_RAT", "id": "A0ABK0L7Z3-1", "name": "Regulator of G-protein signaling 20", "aln": "----------------------------------------------------------------------------------------MPSLPQGNQGYLEEHLSGQAEQAQLLPLIRAEKD-----------------------SNSSIPQDPEN-------------------------------------------------------------------------------------------KGVSQAVTGVKPVESEQTEMRMRQMCSGSE----TQGSVPSQQQGVGGRGSNACCFCWCCCCS----------------------------------------------------------CSCLTVRNQE----DQRPQRAAHELRTD-IPACEESPMPTLEEVCAWAQS--FDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREAN--KSTIEEKAR---------------------------------IIYEDYISILSPKEVSLDSRVREVINRNMVDPSQ----------------------------------------------------------------------------------------------------------------------HIFDDAQLQIYTLMHRDSYPRFMNSTVYKDLLKSLAE-KAVEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76081-1", "uniprot_id": "RGS20_HUMAN", "id": "O76081-1", "name": "Regulator of G protein signaling 20", "aln": "----------------------------------------------------------------------------------------MPQLSQDNQECLQKHFSRPSIWTQFLPLFRAQRYNTDIHQITENEGDLRAVPDIKSFPPAQLPDSPAAPKLFGLLSSPLSSLARFFSHLLRRPPPEAPRRRLDFSPLLPALPAARLSRGHEELPGRLSLLLGAALALPGRPSGGRPLRPPHPVAKPREEDATAGQSSPMPQMGSERMEMRKRQMPAAQD----TPGAAPGQP-GAGSRGSNACCFCWCCCCS----------------------------------------------------------CSCLTVRNQE----DQRPTIASHELRAD-LPTWEESPAPTLEEVNAWAQS--FDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEAN--KNIIEEKAR---------------------------------IIYEDYISILSPKEVSLDSRVREVINRNMVEPSQ----------------------------------------------------------------------------------------------------------------------HIFDDAQLQIYTLMHRDSYPRFMNSAVYKDLLQSLSE-KSIEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40EAI1-1", "uniprot_id": "A0AB40EAI1_DANRE", "id": "A0AB40EAI1-1", "name": "", "aln": "---------------------------------------------------------------------------------MSCNRLILKWVVWPSSVVPSVRRPPYLMWGQLRHLLQACRHDEG------------------YFANGSYENEDEN----------------------------------------------------------------------------------------ENTEDGSKDPISFQPMGSERMEMRKRQMSVQQESVAGTTAPAQNEQPGQGNRASNACCFCWCCCCS----------------------------------------------------------CSCLTVRNEDR---DERNRRASYDFKADGDADFEESPKPTAEEICLWGQS--FDKLMNCPSGRSAFRQFLRTEFSEENMLFWLACEEFRKEAN--KSVIEEKAR---------------------------------IIYEDYISILSPKEVSLDSRVREVINRNMLEPTS----------------------------------------------------------------------------------------------------------------------HTFDDAQLQIYTLMQRDSYPRFMNSPVYKNLLKTVSETQSVES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11972-1", "uniprot_id": "SST2_YEAST", "id": "P11972-1", "name": "Protein SST2", "aln": "MVDKNRTLHELSSKNFSRTPNGLIFTNDLKTVYSIFLICLDLKEKKHSSDTKSFLLTAFTKHFHFTFTYQEAIKAMGQLELKVDMNTTCINVSYNIKPSLARHLLTLFMSSKLLHTPQDRTRGEPKEKVLFQPTPKGVAVLQKYVRDIGLKTMPDILLSSFNSMKLFTFERSSVTDSIIHSDYLIHILFIKMMGAKPNVWSPTNADDPLPCLSSLLEYTNNDDTFTFEKSKPEQGWQAQIGNIDINDLERVSPLAHRFFTNPDSESHTQYYVSNAGIRLFENKTFGTSKKIVIKYTFTTKAIWQWIMDCTDIMHVKEAVSLAALFLKTGLIVPVLLQPSRTDKKKFQISRSSFFTLSKRGWDLVSWTGCKSNNIRAPNGSTIDLDFTLRGHMTVRDEKKTLDDSEGFSQDMLISSSNLNKLDYVLTDPGMRYLFRRHLEKELCVENLDVFIEIKRFLKKMTILKKLIDSKHCDKKSNTSTSKNNIVKTIDSALMKQANECLEMAYHIYSSYIMIGSPYQLNIHHNLRQNISDIMLHPHSPLSEHFPTNLYDPSPASAESAASSISSTEADTLGEPPEVSLKPSKNLSNENCSFKKQGFKHQLKEYKPAPLTLAETHSPNASVENSHTIVRYGMDNTQNDTKSVESFPATLKVLRKLYPLFEIVSNEMYRLMNNDSFQKFTQSDVYKDASALIEIQEKC--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: . : . .: :. . : * *: *.. .:* : * .: * ::* : : : .: :* :: *. * **..*..*:. **: .:: :.: :: . *. *:.* **..** * ** ::.:. .:*: *. *:.* . *: .. ::* **:.**: :* :* ***: : : ", "identical_positions": 41, "similar_positions": 78, "identity": "5.86%" }, { "cls_id": "homologset.agr.MGI:1929869", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9X7-1", "uniprot_id": "D4A9X7_RAT", "id": "D4A9X7-1", "name": "Hypermethylated in cancer 2 protein", "aln": "MVSGPLALRWCPWAGHRDMGPDMELPSHSKQLLLQLNQQRAKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPGDQPSEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGPGRVGTAGMGRPTRSQRLSTASVIQARYPGLVDGRKGHPAPQELPQAKGSDDELFLGSSTQESTHGLG-LGGPAAGEVGLGGCSTSTNGSSGGC-EQELGLDLSKKSPPLPPTTPVPHLTPEDPAQLSDSQRESPPPTSTSALPVSNSTSYVELGATP----DEPMDLEGAEENHLSLLEGQGGQPRKSLRHSARKKDWNKKEPVAGSPFDRRETGSKSSCPGEEGEAPGDRVPNGVLASSAGGGGPSAPSYGEPPYPCKEEEE---NGKDVSEDSGQSGSEGGSGHTGGAHYVYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSTPSSTAYAAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLZ6-1", "uniprot_id": "HIC2_MOUSE", "id": "Q9JLZ6-1", "name": "Hypermethylated in cancer 2 protein", "aln": "MVSGPLALRWCPWAGHRDMGPDMELPSHSKQLLLQLNQQRAKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPSEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGPGRVGTAGIGRPTRSQRLSTASVIQARFPGLVDVRKGHPAPQELPQAKGSDDELFLGTSTQESTHGLG-LGGPAGGEMGLGGCSTSTNGSSGGC-EQELGLDLSKKSPPLPPTTPGPHLTPEDPAQLSDSQRESPAPTSTSALPVGNSASFVELGATP----EEPMDVEGAEENHLSLLEGQGGQPRKSLRHSARKKDWNKKEPVAGSPFDRRETGSKGSCPGEEGEGTGDRVPNGVLASSAGGGGPSA-SYGEQSFPCKEEEE---NGKDGSEDSGQSGSEGGSGHTG-AHYVYRQEGYETVSYGDNVYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSTP-SAAYTADSRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JB3-1", "uniprot_id": "HIC2_HUMAN", "id": "Q96JB3-1", "name": "Hypermethylated in cancer 2 protein", "aln": "MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGGC-EQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPP--AASAPPVANSASYSELGGTP----DEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILAS---GAGPSG-PYGEPPYPCKEEEE---NGKDASEDSAQSGSEGGSGHAS-AHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSAP-SAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90W33-1", "uniprot_id": "HIC2_DANRE", "id": "Q90W33-1", "name": "Hypermethylated in cancer 2 protein", "aln": "----------------------MELPNHAKQLLLQLNQQRAKGYLCDVIIVVENALFRAHKNILAASSIYFKSLILHDNLINLDTDMVNPSVFRQVLDFIYTGKLLSSDQFSDHNFNALLTAASYLQLHDLAALCRKKLKRNGRSLLN-KPTTPTNGRTSRNQRLSSTPVTPNQMSGLKDSEK-TKRHEELIKDDLSEDEMFARNTHCTTSNSLS--------------PSTSKNGSNGSCGMQELGLDLSKKSP--SGSTATEEVSP------SSIPQESPQ---SASESTANSASFDENPNTQNLTAGEPMELGVGECEES--QPPPDVDQHKSSRQVTRQRRQPKSEGKKGEDMER-VTLPNG--VSKRLKVAGERLP----------AGGNG--NSEVSFQCKDEEEGLENGQEQSEESGQSENEGGRNSAN---YVYRQEGFEP-ALGDNLYVCIPCGKGFPSSEELNAHVETHTEEELYIKEE-DDDSYPKEDEVEAEDLSSQITQVHGTETRRFSCSVCNKSYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACEECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****.*:***********:**:******:***::******:***********:*************..:**:*:**********..** :: **.:********** :******:**** *:.: : :. **..*.****::.* : ** * .* :** : . *:**:* : : :.*. *:*.***.*.* ************ . :*. .::* *. : ** ::: ...**:*: * * ***:: .* :. . : :** *: :*:: *.* *. ::* : .:. .:. : *:*:* .* .. .* .: **:*** **:: **:*.** .*** . :. *:*****:*. : ***:******.*******:*************:**** :: . * ******: : .: ::.* *.****:*:**************************************************:***************************************************", "identical_positions": 330, "similar_positions": 129, "identity": "52.3%" }, { "cls_id": "homologset.agr.MGI:1929871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EAN7-1", "uniprot_id": "TE2IP_RAT", "id": "Q5EAN7-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------MAEVMDLGKDPNGPTHSSTLFVREDGSAMSFYVRPSSAKRR-------LSTLILHGGGILCRV---QKPGAVLLAQPG---------------------------------------------------------------------EALAEAS---GDFISTQYILDCVERNEKLELEAYRLG---LTEQASDPKPGASAEGSTEPEPQPLTGRIAYTDADDVAILTYVKE-NARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLQGQEHKYLLGNAPVS-------------------------------------------------------PSSQKLKRKAEQDPEAAD------------------------------------------------------------------------------------------------------SGEPQNKRTPD-------LPEEECVKGETKENGEADN---------------------------------------------------KLFEEATPELG-----EAVVDESP-DFEIHITMCDGDPPTPEED------------------SETQPDEEEEEP----------------------------KVSTQEVGTAIKIIRQLMEKFNLDLSTVTQALLKNSGELEATSSFLESGRRPDGF------PIWCRQDDLDLQKDDDDTRNALVKKYGAQNVARRIEFRKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VL8-1", "uniprot_id": "TE2IP_MOUSE", "id": "Q91VL8-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------MAEAMDLGKDPNGPTHSSTLFVREDGSAMSFYVRPSSAKRR-------LSTLILHGGGTVCRV---QEPGAVLLAQPG---------------------------------------------------------------------EALAEAS---GDFISTQYILDCVDRNEKLDLEAYRLG---LTEQASDPKPGASTEGSTEPEPQPLTGRIAYTDAEDVAILTYVKE-NARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGNAPVS-------------------------------------------------------PSSQKLKRKAEQDPEAAD------------------------------------------------------------------------------------------------------SGEPQNKRAPD-------LPEEECVKGEIKENGEADN---------------------------------------------------KLFEEAAPEFG-----EAVVDESP-DFEIHITMCDGDPPTPEED------------------SETQPDEEEEEP----------------------------KVSTQEVGTAIKVIRQLMEKFNLDLSTVTQALLKNSGELEATSSFLESGRRPDGY------PIWCRQDDLDLQKDDDDTKNALVKKFGAQNVARRIEFRKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYB0-1", "uniprot_id": "TE2IP_HUMAN", "id": "Q9NYB0-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRR-------LSTLILHGGGTVCRV---QEPGAVLLAQPG---------------------------------------------------------------------EALAEAS---GDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYVKE-NARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVS-------------------------------------------------------PSSQKLKRKAEEDPEAAD------------------------------------------------------------------------------------------------------SGEPQNKRTPD-------LPEEEYVKEEIQENEEAVK---------------------------------------------------KMLVEATREFE-----EVVVDESPPDFEIHITMCDDDPPTPEED------------------SETQPDEEEEEEE--------------------------EKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGY------PIWSRQDDIDLQKDDEDTREALVKKFGAQNVARRIEFRKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYJ3-1", "uniprot_id": "TE2IP_DANRE", "id": "Q6NYJ3-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------------MSKKKEASKISPVLFLDPGGQSMRFYVRPGPTKMQ-------LHPLITSGGGNLCRN---QEPGAILLIDPT---------------------------------------------------------------------DATNVTQNTGQKYISTKYILDCVEQNQQLDPNDYAIIIG-------------PSVQTRMALRNQGSGRLGYSSEEDAAILKFIEK-RQQD---AKGNLVWKEMEKRHVTEHSWQSMKDRFLKHLQQKLADKPTKKSPIKRKPLSFTQSPLRKKKVVEISEDESVQK-----------GDCPEAPMATETGSINPPASPERASSPPEEPQAAGQPSQASSNDSQDETCVLVIETPESENPRLDEDAPDASNEHSSLKKKRRKTCKTSTTDSRSSRLEEDPVGQDIPDESNAQSSPKKKRQKACKTS---------TTDSRSSRLEE-------NPDRRDIPDESTEQSSPNKSQMTSKISTSDSGNPIGDQGCDNPHGCNANSSPSKTRQTNSEASTPDSKKLGILAKAAKEFE-----DSDVMDDSEECENPCEVPIAEPSDAQESSATPATLVREPESQAEHHEETQPDSPMSEEERPGPSSAVVPPSLNSSTSCSHIRETPEETLSRDLLEVKEQVINLMRETKKDLVEVTKALLKASGDLKRAQVFLLNGYDHETHG-----PLWTRLDDETLLAADPYELEQLQSKFGEEEVTRRKSFLATDVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11938-1", "uniprot_id": "RAP1_YEAST", "id": "P11938-1", "name": "DNA-binding protein RAP1", "aln": "MSSPDDFETAPAEYVDALDPSMVVVDSGSAAVTAPSDSAAEVKANQNEENTGATAAETSEKVDQTEVEKKDDDDTTEVGVTTTTPSIADTAATANIASTSGASVTEPTTDDTAADEKKEQVSGPPLSNMKFYLNRDADAHDSLNDIDQLARLIRANGGEVLDSKPRESKENVFIVSPYNHTNLPTVTPTYIKACCQSNSLLNMENYLVPYDNFREVVDSRLQEESHSNGVDNSNSNSDNKDSIRPKTEIISTNTNGATEDSTSEKVMVDAEQQARLQEQAQLLRQHVSSTASITSGGHNDLVQIEQPQKDTSNNNNSNVNDEDNDLLTQDNNPQTADEGNASFQAQRSMISRGALPSHNKASFTDEEDEFILDVVRKNPTRRTTHTLYDEISHYVPNHTGNSIRHRFRVYLSKRLEYVYEVDKFGKLVRDDDGNLIKTKVLPPSIKRKFSADEDYTLAIAVKKQFYRDLFQIDPDTGRSLITDEDTPTAIARRNMTMDPNHVPGSEPNFAAYRTQSRRGPIAREFFKHFAEEHAAHTENAWRDRFRKFLLAYGIDDYISYYEAEKAQNREPEPMKNLTNRPKRPGVPTPGNYNSAAKRARNYSSQRNVQPTAN-------------AASANAAAAAAAAASNSYAIPENELLDEDTMNFISSLKNDLSNISNSLPFEYPHEIAEAIRSDFSNE---------------DIYDNIDPDTISFPPKIATTDLFLPLFFHFGSTRQFMDKLHEVISGDYEPSQAEKLVQDLCDETGIRKNFSTSILTCLSGDLMVFPRYFLNMFKDNVNPPPNVPGIWTHDDDESLKSNDQEQIRKLVKKHGTGRMEMRKRFFEKDLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. . . . * **:. .. * ** .** : :. ::: .* : . ::: :: .::: :*: : : . : .. . . :* :*. :: . . .. : . :.: :..*. *:.*. :.: . :. . *.* : .. :: * : ..* : *.. : : . . :: : : :: : ... * : . .:. .: :** : . : : :* : *. : **:* :: . : :* : ** * * . * .*.* .: * * . ", "identical_positions": 38, "similar_positions": 123, "identity": "4.44%" }, { "cls_id": "homologset.agr.MGI:1929872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88941-1", "uniprot_id": "MOGS_RAT", "id": "O88941-1", "name": "Mannosyl-oligosaccharide glucosidase", "aln": "MAR----GERRRRAAAAEGARPLERAR--GAGRRDGRAGGARGSAGGAALAVVVLALAFGLSGRWVLAWLGVRRALTLHPAPSALPPDSSSPAVAP-----EFFWGTYRPHVYFGMKTR--SPKPLLTGLMWAQQGATPGTPPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIYDG--ALRLTTEFVKRSGG-HHGGDWSWRVTVEPQASGTPSFPLVSLFFYVVTDGQE--VLLPEVGAKGQ-LKFISGHTSELGDFRLTLLPPTTPGDTVPKHGSYNVFWSSNPGLPLLTDMVKSHLNSWFHHRPPGASPERYLG---------------LPGSLKWEERGPSGQGQ--FLVQQVTLKAPFSVEFVFESGSARTGRDQASEQLVGGQLTRALESHAAAFKERFERTFQLKEKGLSPEEQALGQVALSGLLGGIGYFYGQGLVLPDTGMEGSEQKMDPSLFP----PVPLFSGVPSRSFFPRGFLWDEGFHQLVVQRWDPHLTREALGHWLGLLN-ADGWIGREQILGDEARARVPPEFLVQRAAHANPPTLLLPVIHMLEGRAPED--------------------------------LAFLRRAFPRLHAWFSWLHQSQAGPVPLSYRWRGRDLALPTLLN-----------PKTLPSGLDDYPRASHPSAAERHLDLRCWVTLGARVLSQLAEELGETEAAAELGPLAASLEAAGSLDELHWAPELGVFADFGNHTKAVQLKSRP---PQG-------------LVRVVGRPPARLQYVD-ALGYVSLFPLLLQLLEPSSPRLGPLLDVLADSRHLWSPFGLRSLSASSLFYKQRNTEHDPPYWRGAVWLNINYLALGALHHYG----RVEGPHKVQAAKLYRELRANVVSNVRQQYQATGFLWEQYSDQDGRGMGCRPFQGWTSLVLLIMAEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UM7-1", "uniprot_id": "MOGS_MOUSE", "id": "Q80UM7-1", "name": "Mannosyl-oligosaccharide glucosidase", "aln": "MAR----GERRRRAAAAEGARPLERAR--AAGRRDGRAGGARGSASGAALAVVVLALAFGLSGRWVLAWLRVRRALTLHPAPSALPPDSSSPAVAP-----ELFWGTYRPHVYFGMKTR--SPKPLLTGLMWAQQGATPGTPPKLRHTCEQGDGVGPYGWEFHDGRTFGRQHIHDG--ALRLTTEFVKRPGG-QHGGDWSWRVTVEPQASGTPSFPLVSLFFYVVTDGQE--VLLPEIGAKGQ-LKSISGHTSELGDFRLTLLPPTSPGDTVPKHGSYNVFWSSNPGLPQLTDMVKSRLNSWFQHRPPGASPDRYLG---------------LPGSLKWEERGPSGQGQ--FLIQQVTLKAPFSVEFVFESGSAATGGNQASGRLVGSQLTQALESHAAAFKERFEKTFQLKEKGLSPEEQALGQVALSGLLGGIGYFYGQGLVLPDTSMEGSEQKMDPALFP----PVPLFSGVPSRSFFPRGFLWDEGFHQLVVQRWDPHLTREALGHWLGLLN-ADGWIGREQILGDEARARVPPEFLVQRAAHANPPTLLLPVVHMLEGHDPDD--------------------------------LAFLRKAFPRLHAWFSWLHQSQAGPVPLSYRWRGRDLALPTLLN-----------PKTLPSGLDDYPRASHPSTAERHLDLRCWVALGARVLSQLAEQLGETEAAAELGPLAASLEEPGSLDELHWAPELGVFADFGNHTKAVQLKSRP---PQG-------------LVRVVGRPPPRLQYVD-ALGYVSLFPLLLQLLDPSSPRLGPLLDVLADSRHLWSPFGLRSLSASSLFYKQRNTEHDPPYWRGAVWLNINYLALGALHHYG----HVEGPHKVQAAKLYHELRANVVRNVRQQYQATGFLWEQYSDQDGRGMGCRPFQGWTSLVLLIMAEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13724-1", "uniprot_id": "MOGS_HUMAN", "id": "Q13724-1", "name": "Mannosyl-oligosaccharide glucosidase", "aln": "MAR----GERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAP-----DLFWGTYRPHVYFGMKTR--SPKPLLTGLMWAQQGTTPGTP-KLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDG--ALRLTTEFVKRPGG-QHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKE--VLLPEVGAKGQ-LKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLG---------------LPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFP----PVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLN-ADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDD--------------------------------LAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLN-----------PKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRP---PQG-------------LVRVVGRPQPQLQYVD-ALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYG----HLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZ04-1", "uniprot_id": "Q9VZ04_DROME", "id": "Q9VZ04-1", "name": "Mannosyl-oligosaccharide glucosidase", "aln": "MARNTGSSSGSTPAASSSGSSAAAAAAAAAAAAAASNAKQKQRSPRFSLSSNLILDKWKTMIGCVCLAIASYFGYLGYLETRVNTPFDHQKMVVHAGLEQPDRYWGSYRPLTYFGMKTR--DPHSLVMGLMWYTPSNLGPGGQGIRHWCEQGDKLDSYGWTHHDGRSFGVQEIQDL--PFELKTSFVKYPEGKQYGGDWTARISVRNTTRAWDKS--ISLIWYVALDERTNGHIKYVSDDKSP-EPGVYGEAQGLGEFQVRFHAVKG----KILHKSY--LSTVAPSLAKLKDTLFSHFRAFADKRG-----NRFIG---------------LPGEIVSQNGLPSSNPEPNFIAIQITAEVDFTLDITYQSTSGFSLGESIPKPPTGRAYQDSLQAKIAQFEQRFEDRFQLKQKGHSPEEVRFARNALSNLLGGIGYFYGSSRVQ-------SVYTKNPVPYW----KAPLYTAVPSRSFFPRGFLWDEGFHGLLISAWDIDIELDIICHWFDLLN-VEGWIPREQILGVEALAKVPEEFVTQRNSNANPPTFFLTLKKLLTSHRAELSQNGR---------------------------LATLERLYPRVQAWFNWFNTTQRGEVLGTYLWRGRNATTTRELN-----------PKSLSSGLDDYPRASHPTDKERHLDLRCWIALAAGVMAELSTLLGKDD--AKYYETASYLTDNVRLNRLHLAPYSEQYADWGLHTDQVKLKRPPSMAPQQQQRHHHQHYQLPEMQRVTG-ELPTYQFVDSAFGYVSLFPLLLEQLDHDSPYLTKLLNDLRDPEQLWTNYGLRSLSKRSPLYMQRNTEHDPPYWRGPIWININYLAAKALHHYG----KIDGPNAALARQIYAELRDNLVGNILRQYKRSGYLWEQYDDTSGEGKGCNPFTGWTATVVLLMAEQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53008-1", "uniprot_id": "CWH41_YEAST", "id": "P53008-1", "name": "Mannosyl-oligosaccharide glucosidase", "aln": "----------------------------------------------------MLISKSKMFKTFWILTSIVLLASATVDISKLQEFEEYQKFTNES------LLWAPYRSNCYFGMRPRYVHESPLIMGIMWFNS-LSQDGLHSLRHFATPQDKLQKYGWEVYDPRIGGKEVFIDEKNNLNLTVYFVKSKNG----ENWSVRVQGEPLDPKRPSTASVVLYFSQNGGEIDGKSSLAMIGHDGPNDMKFFGYSKELGEYHLTVKDNFGHYFKNPEYETMEVAPGSDCSKTSHLSLQIPDKEVWKARDVFQSLVSDSIRDILEKEETKQRPADLIPSVLTIRNLYNFNPGNFHYIQKTFDLTKKDGFQFDITYNKLGTTQSISTREQVTELITWSLNEINARFDKQFSFGEGPDSIESVEVKRRFALETLSNLLGGIGYFYGNQLIDRETEFDESQFTEIKLLNAKEEGPFELFTSVPSRGFFPRGFYWDEGFHLLQIMEYDFDLAFEILASWFEMIEDDSGWIAREIILGNEARSKVPQEFQVQNPNIANPPTLLLAFSEMLSRAIENIGDFNSDSYHQVMFNSRTAKFMTNNLEANPGLLTEYAKKIYPKLLKHYNWFRKSQTGLIDEYEEILEDEGIWDKIHKNEVYRWVGRTFTHCLPSGMDDYPRAQPPDVAELNVDALAWVGVMTRSMKQIAHVLKLTQDEQRYAQIEQEVVEN--LDLLHWSENDNCYCDISIDPEDDEIREFVC-----------------------------------HEGYVSVLPFALKLIPKNSPKLEKVVALMSDPEKIFSDYGLLSLSRQDDYFGK-----DENYWRGPIWMNINYLCLDAMRYYYPEVILDVAGEASNAKKLYQSLKINLSNNIYKVWEEQGYCYENYSPIDGHGTGAEHFTGWTALVVNILGRF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : *: : : .. . . *..**. ****:.* .*: *:** :** . * : *** :* * : : * :.*.. *** * :*: *: . : * : . . .. . * :. **:::. . : : . . . . . : : . : :*. : .: . : :: . .:: . : . . :*: * ::*. .. : :. :**.**********. : * . *::.****.****** ****** * : :* : : : *: ::: .*** ** *** ** ::** ** .*. *****::*.. .:* : .: *:: :.*:. :* * : : : .: *.**:******. * * ::* .*: : : : .:: * : . : *: ** : :.* . ... ::: ****::*: *. : *. * :: : *..:::: :** **: . : : * ****.:*:*:***. *:::* . . * ::: .*: *: *: : :: *: :*:*. .*.* *.. * ***: *: :.. ", "identical_positions": 154, "similar_positions": 209, "identity": "16.4%" }, { "cls_id": "homologset.agr.MGI:1929878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8Y7C5-1", "uniprot_id": "A0A8J8Y7C5_RAT", "id": "A0A8J8Y7C5-1", "name": "", "aln": "MLPAR-VRLLTPHLLLLLVQLSPAGGHRTTGPRFLISDRDPPCNPHCPRTQPKPICASDGRSYESMCEYQRAKCRDPALAVVHRGRCK---------------------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPIS---------------------------------------GSSVQNKTPVCSG---------------------------TGGR------------YDGSKPTPTMETQPVF------------------------------------------------------------------------------------------------------------------------DGDEITAPTLWIKHLVIKDSKLNNTNVRNSEKVHSCDQERQSALEEARQNPREGIVIPECAPGGLYKPVQCHQSTG--YCWCVLVDTGRPLPGTSTRYVMPSCESDARAKSVEVDDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVAHWYFSQLDSNSSDDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKAISLPELKGCLGVS-KEGESELHVIP--DGSQTGTLSLGCSNCRCQEAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLY1-1", "uniprot_id": "SMOC1_MOUSE", "id": "Q8BLY1-1", "name": "SPARC-related modular calcium-binding protein 1", "aln": "MLPAR-VRLLTPHLLLVLVQLSPAGGHRTTGPRFLISDRDPPCNPHCPRTQPKPICASDGRSYESMCEYQRAKCRDPALAVVHRGRCK---------------------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPIS---------------------------------------GSSVQNKTPVCSGPV-----------------TDKPLSQGNSGRKVSFRFFLTLNSDDGSKPTPTMETQPVF------------------------------------------------------------------------------------------------------------------------DGDEITAPTLWIKHLVIKDSKLNNTNVRNSEKVHSCDQERQSALEEARQNPREGIVIPECAPGGLYKPVQCHQSTG--YCWCVLVDTGRPLPGTSTRYVMPSCESDARAKSVEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVAHWYFSQLDSNSSDDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVS-KEGGS-LGSFP--QGKRAGTNPFIGRLV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4F8-1", "uniprot_id": "SMOC1_HUMAN", "id": "Q9H4F8-1", "name": "SPARC-related modular calcium-binding protein 1", "aln": "MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCK---------------------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPIS---------------------------------------GSSVQNKTPVCSGSV-----------------TDKPLSQGNSGRK-----------DDGSKPTPTMETQPVF------------------------------------------------------------------------------------------------------------------------DGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTG--YCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVS-KEGRLV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKH8-1", "uniprot_id": "A0A8M9PKH8_DANRE", "id": "A0A8M9PKH8-1", "name": "", "aln": "MNCHN--LALCVFMYLMVMRLPAASTQKSTGPRWLIGDRESPCSTSCSRSHGKPVCGSDGRSYDTNCDLERAKCRDRTLTLAHRGRCKGKNWVRIDQPLLVPTLVSEVKELTGMKEAGQTKCRTERIQALEQAKKPQESIFIPECNDDGTFAQVQCHTLTGYCWCVTTDGKPVS---------------------------------------GSSVQNKTPVCSGNFREFMGTHAGTSGLSGSVTDKPPGPPSSGKKVSFRFFLTLNPDDGSKPTPTMEPHVVP------------------------------------------------------------------------------------------------------------------------EGEEITAPTLWIKQLVYKENKQNSSNSRKSEKVPSCDQERQTAQDEARQNPREAIFIPDCGLQGLYKPVQCHQSTG--YCWCVLVDTGRPIPGTSARYKKPECDSAARSRDTEMEDPFRDRDLTGCPEGKKVEFITSLLDALTTDMVQAINSPTPSGGGRFVEPDPSHTLEERVVHWYFAQLDNNGSHDINKKEMKPFKRYVKKKAKPKRCARKFTDYCDLNKDKTISLQELKGCLGVN-KEGSTTSSSQGTRQGTNLFSKVFGPEDRKLQKMRQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E9E0-1", "uniprot_id": "Q0E9E0_DROME", "id": "Q0E9E0-1", "name": "", "aln": "---------MLARCVLFVTWLAVFIATGKSDDQLMKLPACAAKQGECDDNEG-PVCGTDGQTYPTRCHLLRAQCGGHQVSLKYSGSCN---------------------------------ACLEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNG-CWCSDSQGRPIADDNKQFRRKGKLRCRANRRDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSDSHILEWQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVCFTKEFHNRSAVVNLLASSAATAPPHSTHYSIHNTNVNGHHRGHTNTIGTGVNPHSYSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIPSLYMLNSK-PETASQDLENDSNCWMDQSVTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKRPQCDESVAVR-----------PMKGCTEPRKTQFLKELKAYLNTSLLPSSTTGSNS--------SMWKTDDERIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLAEWLNCLQATPRESATTAKPAQSNETASPKFQGVNPVERYLKD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: *. .:. : : . . * .. *:*.:**::* : *. **:* . : : : * *: . * : .: :: : . *:*.* .**.*: :**: .* *** .:*:*:: *** ..*. : . . :*.* * : : :* ::.:. * * :.* .: :. *: .* ::. : :* :. :. :.:*:* * *: :**:.**. ***** ***:.:****.: *.*:. . : : **.* :* :*:..* *.*.:: : .: : : . :* :**:. * **.* ... :::* * *: *.. :: ::*.:::. ***:* ** *** * .** .. :*. ", "identical_positions": 98, "similar_positions": 145, "identity": "14.41%" }, { "cls_id": "homologset.agr.MGI:1929881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FPL2-1", "uniprot_id": "F7FPL2_RAT", "id": "F7FPL2-1", "name": "", "aln": "MLPPQLCWLPLLAALLPPVPAQKFSALTFLRVDQDKDRDCSLDCPSSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAHRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISG---------------------TAVAHKTPRCPGSINEKLPQREGAGKAVSLQIFSVLNSDDAAAPALETQPQ--------------------------------------------------------------------------------------------------------------------------------------------------------GDEED--------IASRYPTLWTEQVKSRQNKTNKNSASSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTG--YCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKNRPLQGCPGAKKHEFLTSVLDALSTDMVHAVSDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDMNNDKSITVQELMGCLGVTREEGKANTRKRHTPRGNAESTSSNRQPRKQG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CD91-1", "uniprot_id": "SMOC2_MOUSE", "id": "Q8CD91-1", "name": "SPARC-related modular calcium-binding protein 2", "aln": "MLPPQLCWLPLLAALLPPVPAQKFSALTFLRVDQDKDRDCSLDCPSSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAHRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISG---------------------TAVAHKTPRCPGSINEKVPQREGAGKA-----------DDAAAPALETQPQ--------------------------------------------------------------------------------------------------------------------------------------------------------GDEED--------IASRYPTLWTEQVKSRQNKTNKNSASSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTG--YCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKNRPLQGCPGAKKHEFLTSVLDALSTDMVHAVSDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDMNNDKSITVQELMGCLGVTREEGKANTRKRHTPRGNAESSSSNRQPRKQG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3U7-1", "uniprot_id": "SMOC2_HUMAN", "id": "Q9H3U7-1", "name": "SPARC-related modular calcium-binding protein 2", "aln": "MLLPQLCWLPLLAGLLPPVPAQKFSALTFLRVDQDKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISG---------------------TAVAHKTPRCPGSVNEKLPQREGTGKT-----------DDAAAPALETQPQ--------------------------------------------------------------------------------------------------------------------------------------------------------GDEED--------IASRYPTLWTEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTG--YCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKGRQLQGCPGAKKHEFLTSVLDALSTDMVHAASDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELMGCLGVAKEDGKADTKKRHTPRGHAESTS-NRQPRKQG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E9E0-1", "uniprot_id": "Q0E9E0_DROME", "id": "Q0E9E0-1", "name": "", "aln": "MLARCVLFVTWLAVFIATGKSD--DQLMKLPACAAKQGECDDNEG-----PVCGTDGQTYPTRCHLLRAQCGGHQVSLKYSGSCN---ACLEAVKFARRQQERD-PGYFVPRCRKDGNFAAMQCYGNNG-CWCSDSQGRPIADDNKQFRRKGKLRCRANRRDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSDSHILEWQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVCFTKEFHNRSAVVNLLASSAATAPPHSTHYSIHNTNVNGHHRGHTNTIGTGVNPHSYSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIPSLYMLNSKPETASQDLENDSNCWMDQSVTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKRPQCDESVAVR-----------PMKGCTEPRKTQFLKELKAYLNTSLLPSSTTGSNSSMWKTD-------DERIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLAEWLNCLQATPRES-ATTAKPAQSNETASPKFQGVNPVERYLKD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ::. ** ::.. :: . * * . *: :*. : *:*.:**:*: :**.: **:* . *:.: : *.*: *: *:::.* .:: *:*.*..**.:: :**:. .* *** .:****:. .:*: *.: .* ... *: : :..:.* *:*:* :: *:*: : *.. . : :. *.* ::. :*** : :. :.:*:* .* *: :**:.**. ***** ***:.*****.: ::*:**::. .: ::**. .:* :**..: *.*.:: : : *.** :: :**:. * ****.. . .::* * *: :: . *: ::* **: .***:*.**.*:: * :.** .: .:. * * * .. *... . :* :: ", "identical_positions": 118, "similar_positions": 171, "identity": "18.32%" }, { "cls_id": "homologset.agr.MGI:1929882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHT6-1", "uniprot_id": "AS3MT_RAT", "id": "Q8VHT6-1", "name": "Arsenite methyltransferase", "aln": "MAAPRDA-EIHKDVQNYYGNVLKTSADLQTNACVTPAKGVPEYIRKSLQNVHEEVISRYYGCGLVVPEHLENCRILDLGSGSGRDCYVLSQLVGQKGHITGIDMTKVQVEVAKAYLEYHTEKFGFQTPNVTFLHGQIEMLAEAGIQKESYDIVISNCVINLVPDKQKVLREVYQVLKYGGELYFSDVYASLEVSEDIKSHKVLWGECLGGALYWKDLAVIAKKIGFCPPRLVTANIITVGNKELERVLGDCRFVSATFRLFKLPKTEPAGRCQVVYNGGIMGHEKELIFDANFTFKEGEAVEVDEETAAILRNSRFAHDFLFTPVEASLLAPQ------TKVIIRDPFKLAEESDKMKPRCAPEGTGGCCGKRKSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WU5-1", "uniprot_id": "AS3MT_MOUSE", "id": "Q91WU5-1", "name": "Arsenite methyltransferase", "aln": "MAASRDADEIHKDVQNYYGNVLKTSADLQTNACVTRAKPVPSYIRESLQNVHEDVSSRYYGCGLTVPERLENCRILDLGSGSGRDCYVLSQLVGEKGHVTGIDMTEVQVEVAKTYLEHHMEKFGFQAPNVTFLHGRIEKLAEAGIQSESYDIVISNCVINLVPDKQQVLQEVYRVLKHGGELYFSDVYASLEVPEDIKSHKVLWGECLGGALYWKDLAIIAQKIGFCPPRLVTADIITVENKELEGVLGDCRFVSATFRLFKLPKTEPAERCRVVYNGGIKGHEKELIFDANFTFKEGEAVAVDEETAAVLKNSRFAPDFLFTPVDASLPAPQGRSELETKVLIRDPFKLAEDSDKMKPRHAPEGTGGCCGKRKNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBK9-1", "uniprot_id": "AS3MT_HUMAN", "id": "Q9HBK9-1", "name": "Arsenite methyltransferase", "aln": "MAALRDA-EIQKDVQTYYGQVLKRSADLQTNGCVTTARPVPKHIREALQNVHEEVALRYYGCGLVIPEHLENCWILDLGSGSGRDCYVLSQLVGEKGHVTGIDMTKGQVEVAEKYLDYHMEKYGFQASNVTFIHGYIEKLGEAGIKNESHDIVVSNCVINLVPDKQQVLQEAYRVLKHGGELYFSDVYTSLELPEEIRTHKVLWGECLGGALYWKELAVLAQKIGFCPPRLVTANLITIQNKELERVIGDCRFVSATFRLFKHSKTGPTKRCQVIYNGGITGHEKELMFDANFTFKEGEIVEVDEETAAILKNSRFAQDFLIRPIGEKLPTSGGCSALELKDIITDPFKLAEESDSMKSRCVPDAAGGCCGTKKSC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *** **:****.***:*** *******.*** *: **.:**::******:* *******.:**:**** ********************:***:******: *****: **::* **:***:.****:** ** *.****:.**:***:************:**:*.*:***:**********:***:.*:*::****************:**::*:************::**: ***** *:************** .** *: **:*:***** ******:*********** * *******:*:***** ***: *: .* :. * :* *******:**.**.* .*:.:*****.:*.*", "identical_positions": 269, "similar_positions": 70, "identity": "71.54%" }, { "cls_id": "homologset.agr.MGI:1929883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI08-1", "uniprot_id": "BIN3_MOUSE", "id": "Q9JI08-1", "name": "Bridging integrator 3", "aln": "MSWIPFKIGQPKK------QIVSKTVERDFEREYGKLQQLEEQTKRLQKDMKKSTDADLAMSKSAVKISQDLLSNPLCEQDQDFLHMVTALDTAMKRMDAFNQEKVNQIQ----KTVIEPLKKFSSIFPSLNMAVKRREQALQDYGRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNKQLLDEMPRFYGSRLDYFQPSFESLIRAQVIYYSEMHKIFGDLTQQLDQPGHSDEQR---ERENETKLSELRALSIVADD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FW8-1", "uniprot_id": "BIN3_RAT", "id": "Q68FW8-1", "name": "Bridging integrator 3", "aln": "MSWIPFKIGQPKK------QIVSKTVERDFEREYGKLQQLEEQTKRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDFLRMVTALDTAMKRMDAFNQEKVNQIQ----KTVIEPLKKFGSIFPSLNMAVKRREQALQDYGRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNKQLLDEMPRFYNSRLDYFQPSFESLIRAQVIYYSEMHKIFGDLTQQLDQPGHSDEHR---ERENETKLSELRALSIVADD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQY0-1", "uniprot_id": "BIN3_HUMAN", "id": "Q9NQY0-1", "name": "Bridging integrator 3", "aln": "MSWIPFKIGQPKK------QIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQ----KTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQR---ERENEAKLSELRALSIVADD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25343-1", "uniprot_id": "RV161_YEAST", "id": "P25343-1", "name": "Reduced viability upon starvation protein 161", "aln": "MSWEGFKKAINRAGHSVIIKNVDKTIDKEYDMEERRYKVLQRAGEALQKEAKGFLDSLRAVTASQTTIA-EVISNLYDDSKYVAGGGYNVGNYYLQCVQDFDSETVKQLDGPLRETVLDPITKFSTYFKEIEEAIKKRDHKKQDFDAAKAKVRRLVDKPAKD--ASKLPRAEKELSLAKDIFENLNNQLKTELPQLVSLRVPYFDPSFEALIKIQLRFCTDGYTRLAQIQQYLDQQSRDDYANGLLDTKIEELLGQMTSLDICALGIK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** . : : * **:::::: * : : *:. . ***: * *: *:: * ..*: :::** :.. .. : :: :: *:.*.*:*:: :**::*:.**.: * .:: *:*:*:: **: :***.: :* .. :** :*.:** .:: ** *.** *:*:: . *: **:****:**: *: : :: :. :.:: : *** .:.* . : : * *.:: :*.* * . ", "identical_positions": 70, "similar_positions": 100, "identity": "26.12%" }, { "cls_id": "homologset.agr.MGI:1929885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EP64-1", "uniprot_id": "TNMD_MOUSE", "id": "Q9EP64-1", "name": "Tenomodulin", "aln": "MAKNPPENCEGCHILNAEALKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVSKKTYDMEHTFYSNGEKKKIYMEIDPITRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIAVSELQDFEEDGEDLHFPTSEKKGIDQNEQWVVPQVKVEKTRHTRQASEEDLPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ESC2-1", "uniprot_id": "TNMD_RAT", "id": "Q9ESC2-1", "name": "Tenomodulin", "aln": "MAKNPPENCEGCHILNAEALKSKKIRKSLKICGLVFGILALTLIVLFWGSKHFWPEVSKKTYGMEHTFYSNGEKKKISMEIDPITRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIAVSELQDFEEDGEDLHFPTSEKKGIDQNEQWVVPQVKVEKTRRTRQASEEDLPVNDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2S6-1", "uniprot_id": "TNMD_HUMAN", "id": "Q9H2S6-1", "name": "Tenomodulin", "aln": "MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEKKGIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********.********:***** *******************************.**:*.************** *****:***********************************************************************************************************:*********:*******:.*****:****************::******:**:************************************************************************", "identical_positions": 300, "similar_positions": 15, "identity": "94.64%" }, { "cls_id": "homologset.agr.MGI:1929895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6Q0N0-1", "uniprot_id": "CSTN1_RAT", "id": "Q6Q0N0-1", "name": "Calsyntenin-1", "aln": "----MLRRPAPALARAVRLLLAGLLYGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDSPLRFAG----------EICGFKIHGQNVPFDAVVVDKSTGEGIIRSKEKLDCELQKDYTFTIQAYDCGKGPDGTGVKKSHKATVHIQVNDVNEYAPVFKEKSYKAAVVEGKQHGSILRVEAVDADCSPQFSQICSYEILTPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISVKPTCSPGWQGWSSRIEYEPG-TGALAVFPSIHLETCDEPVAS-----VQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTSELLPSPSSSFNWTVGLPTDNGHDSDQVFEFNGTQAVRIPDGVVTLD--PKEPFTISVWMRHGPFGRK----KETILCSSDKTDMNRHHYSLYVHGCRLIFLLRQDPSEEKK--YRPAEFHWKLNQVCDEDWHHFVLNVEVPS-VTLYVDGVSHEP--------FSVTEDYPLHPTK-IETQLVVGACWQ-------------------GGDLHMTQFFRGNLAGLTVRSGKLADKKVIDCLYTCKEGLDLQVPEDGNR------GVQIQTSSSQAVLTLEGENVGELDKAMQHISYLNSRQFPTPGIRRLKITSTVKCFNEAACIEVPPVEGYVMVLQPEEPKISLSGVHHFARAASEFESPEGVSLFPELKIISTITREVE--------PEADGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNAEQESLEVDVARLQQKGIEVNH--SDLGVVFTGVETMASYEEVLHLLRYRNWHTRSLLDRKFKLICSELNGRYLSNEFKVEVNVIHTANPVEHANHMAAQPQFVHPEHRSFVDLSGHNLASPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHQRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEE----------------EEDITSAESESSE--EEEGGPGDGQNTTRQQQLEWDYSTLSY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPL2-1", "uniprot_id": "CSTN1_MOUSE", "id": "Q9EPL2-1", "name": "Calsyntenin-1", "aln": "----MLRRPAPALAPAVRLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDSPLRFAESFEVTVTKEGEICGFKIHGQNVPFDAVVVDKSTGEGIIRSKEKLDCELQKDYTFTIQAYDCGKGPDGTGVKKSHKATVHIQVNDVNEYAPVFKEKSYKAAVVEGKQHSSILRVEAVDADCSPQFSQICSYEILTPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISVKPTCSPGWQGWSSRIEYEPG-TGALAVFPSIHLETCDEPVAS-----VQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTSELLPSPSSSFNWTVGLPTDNGHDSDQVFEFNGTQAVRIPDGVVTLD--PKEPFTISVWMRHGPFGRK----KETILCSSDKTDMNRHHYSLYVHGCRLVFLLRQDPSEEKK--YRPAEFHWKLNQVCDEDWHHFVLNVEVPS-VTLYVDGIPHEP--------FSVTEDYPLHPTK-IETQLVVGACWQEYSGVESGNETEPATMASAGGDLHMTQFFRGNLAGLTVRSGKLADKKVIDCLYTCKEGLDLQVPEDANR------GVQIQASSSQAVLTLEGDNVGELDKAMQHISYLNSRQFPTPGIRRLKITSTVKCFNEAACIEVPPVEGYVMVLQPEEPKISLSGVHHFARAASEFESAEGISLFPELRIISTITREVE--------PEADGSEDPTVQESLVSEEIVHDLDTCEVTVEGDELNAEQESLEVDVTRLQQKGIEASH--SDLGVVFTGVETMASYEEVLHLLRYRNWHTRSLLDRKFKLICSELNGRYLSNEFKVEVNVIHTANPVEHANHMAAQPQFVHPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHQRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEE----------------EEDITSAESESSE--EEEGGPGDGQNATR--QLEWDDSTLSY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94985-1", "uniprot_id": "CSTN1_HUMAN", "id": "O94985-1", "name": "Calsyntenin-1", "aln": "----MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAESFEVTVTKEGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPG-TGALAVFPNIHLETCDEPVAS-----VQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVSVS--PKEPFTISVWMRHGPFGRK----KETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQDPSEEKK--YRPAEFHWKLNQVCDEEWHHYVLNVEFPS-VTLYVDGTSHEP--------FSVTEDYPLHPSK-IETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGR------GVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEFESSEGVFLFPELRIISTITREVE--------PEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEVSS--SELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEE----------------EDDITSAESESSE--EEEGEQGDPQNATRQQQLEWDDSTLSY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R520-1", "uniprot_id": "CSTN1_DANRE", "id": "F1R520-1", "name": "Calsyntenin-1", "aln": "----MRIRGVKPFASAVGLLLG-LLY--AVDAAKVNKHKPWIETTYHGIVTENDDKVLLDPPLIALDKDAPLRYAG----------EICGFRIHGQNVPFEAVVLDKSTGEGVIRAKDKLDCELQKEHTFTIQAYDCGEGPDGGNMKKSHKATVHIQVNDVNEYSPVFKEKSYKATVIEGKKYDSIMKVEAVDADCSFQFSQICSYEIVTPDVPFTIDKDGNIKNTEKLNYGKERMYKLTVTAYDCGKNRASEDVLVKINIKPTCKPSWQGFNKRIEYEPG-TGSLALFPSMHLETCEEPITS-----IQASIMLETNHIGKGCDRDTYSEKSLHKLCGASSGTVELLPAPSNSANWTVGLPTDNGHDSDQVFEFNGTQAIKVPEGVVSTT--LKEPFTISVWMRHGPGGRE----KETILCNSDKTEMNRHHYSLYVHNCRLVLLLRQEPTESES--YKPAEFHWKLDQVCDKEWHHYVLNIEFPA-VTLFVDGGTFEP--------FLVTEDYPLHTSK-IETQLTIGACWQ-------------------GGSARMTQFFRGNLAGLMIRSGKLENKKVIDCLYTCKEGLDVQLPEEVAS------AVKVEFNPNQSSLSLEGDDIESFEKVMQHISYLNSRQFPTPGIRHLRVSTTVKCFNEETCISVPDSEGYVMVLQPEEPKISLSGIDHFARGAAEFESVEGVTLFPELRIVSTITREVEVEAEAE--TEAEGEDDPTVQETVVSEEIMHNLDTCEVTVVGEDLNGDHESLEVDLAQIQQRALEMSS--SNVGMVITGVNTMANYEQVLHLIRYRNWHTEALFDRKFKLVCSELNGRYISNEFKVEVNVIHTANPMDHANNAMVQPQFISQVQHASVDLSGHNLVNTHQASVVPSAATIVIVVCVSFLVFMIILGVFRIRAAHQRTMRDQENGKENEMDWDDSALTITVNPMETYEDQHSSEEEGDEEEEE-SEDGEE----------------EDDITSAESDSSE--DEAGEQEDQQGSSRQQQLEWDDSTLTY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V498-1", "uniprot_id": "CSTN1_DROME", "id": "Q9V498-1", "name": "Calsyntenin-1", "aln": "MTFHKTFGYGCIVLICFELLFAGVETSSENDDEYLTQKEIILEKSYHGLIRENETLVEITP-LIKVNEE-----------------KICNFHILKKPYHEIPFKIELVNNLGILKARRTLNCENRKSYHFEICAIYCDGTP-------SNTANVHITVIDVNEYAPTFLEPSYVIEVDEGRLYNEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSVVAYDCAMK-ESAPIMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCDISCKNEEDLRIHSSIALKTKHISFGCDRDISN-------CTSGQKVKDLLP---HGAEWTKELSYDEGLEP--IFHFDGSTGVVVPATVIDHYDFSSQPFSILTLFRHNSQVEINKHVKEHIVCSADDHKMNRHHMALFVRNCRLIFLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFENSIENRHSNPEVIDDWPLHAAHGVNTSLAIGACYQS-------------------LENRLKHGFNGDISEVKVSLNSVLTAEDIKCGTTCAEHLLAPKPLQSNNEKSYSDNSQIKENIEMNEIYISAKNKHDIEQFMRKVQYINTKQKPTVGRRNIEVLTTLNCKNES-SLRLPPIETYIMVNEPIAP---LGIDIDVVSASLETSDLTPPSYSPKIAISGTSNKLVSYQEIKLGVHILEKTCIDSVSKNNGKLEEKNHIDSCSVVVFP-SLNPDHEDIKIDGDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNRVFKLSCAQQSSQYKSGEYTLTLTVLHPKQTLFKSTNVLPS----SLSKVNFIGNTDNETSFHRNSGSVNGNDNNQPTESKVYSYSLLHTNNVQEPKSHIHSFIHKAEGSHVTMLIILVSVFLAVLLCGVSIARLKNNQKYIEHHQPCPKISDDGLIWDDSALTITINPMQADVTSDASSESENSESEDEEALKDGFTHINQLEWDNSNIFQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . **:. : :.::: :* :***:: **: * : * ** :::: :**.*:* : .. :: .. *::::: .*:** :*.: * * * *. * *:.*.*** * *****:*.* * ** * **: :..*::*** * **: *.::*.***:. * **::*::* ***** *.: .: : *:*.****. : : ::*.*.:: .* . : * .**:* .* * :* :**. :*: *: . . ::::: *:*.**. ***** . * :. . :*** . :** *. *:* :. :*.*:*: .: :* *: .:**:* . :**.. . ** *:*.:*. .***** :*:*:.***::*:*:: .* . : ***::**: :***::***:***:* .: * *::** .* * :*:***.:: ::*.*.:***:* . ::.: *.*::: : : ..: : *.* ** * * : ::: . : :...: .::: *:::.*:*::* ** * *.:.: :*::* ** .: :* : *:** :* * *. ... .: * .. *:: * .* .: *. : :*.:. . * :.:*:*.*.* .** ::*.:::* . . .:: . .. *: : * :*::.* :**: : * * :. ::* *** *:: ..:* *.*:.: :.*:*. :.: ::.: . : :. :.:: : . * . . . . : :: . .: :* ::: .: *.. * :: ::* . : ..::: *..: .: .:: : *:** *..** :. . :. :: ***** *.: ", "identical_positions": 243, "similar_positions": 354, "identity": "23.28%" }, { "cls_id": "homologset.agr.MGI:1929897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDA1-1", "uniprot_id": "CSTN2_RAT", "id": "Q8VDA1-1", "name": "Calsyntenin-2", "aln": "----MLPGRLCLVPLLLALGVGSGGGSGDGGDSRRRRLLAAKVNKHKPWIETSYHGVITENNDTVILDPTIVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPQEAAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAIVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQRQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPG-SGSMPLFPGIHLETCDGAVS-----SLQVTAELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKIPDGIVPKN--LTDQFTITMWMKHGPSPGV-RAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADT--FRPAEFHWKLDQICDKEWHYYVINVEFP-VVTLYMDGATYEP--------YLVTNDWPIHPSH-IAMQLTVGACWQGGEVAKPRFAQFFHGSLASLTIRPGKMESQKVISCLQACKEG------LDINSLESLGRGIKYHFNPSQSILVMEGDDIGNINQALQKVSYINSRQFPTAGVRRLRLSSKVQCFGEDVCISIPDVDAYIMVLQAIEPQ-------ITLQGTERFWRPAAQFESARG-----VTLFPDIKIISTFAKTEASGDLRATGTAPKSAVLEEMLHNLDFCDILVLGGDLDPRQECLELNHSELHQRHLDATN--STAGYSIYGVGSMSRYEQVLHHLRYRNWHPTSLETRRFQIKCSELNGRYTSNEFNLEVSVLHEVRVSDTEHVNHLIVQPPFLQSVYHPETRSSIQ--RSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAK-EAEMDWDDSALTITVNPMEKHEGPGHGEDE-TEGEEEEEAEE-------------------GMSSSSSGSDDSEEEEEEGMGRVRHGQSGTSSQRPERSTWNTAGVINIWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER65-1", "uniprot_id": "CSTN2_MOUSE", "id": "Q9ER65-1", "name": "Calsyntenin-2", "aln": "----MLPGRLCLVPLLLALGVGSGGGSGDGGDSRRRRLLVAKVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPREAAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAIVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPG-SGSMPLFPSIHLETCDGAVS-----SLQVTAELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKIPDGIVPKN--LTDQFTITMWMKHGPSPGV-RAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADT--FRPAEFHWKLDQICDKEWHYYVINVEFP-VVTLYMDGATYEP--------YLVTNDWPIHPSH-IAMQLTVGACWQGGEVAKPRFAQFFHGSLASLTIRPGKMESQKVISCLQACKEG------LDINSLESLGRGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLRLSSKVQCFGEDVCISIPDVDAYIMVLQAIEPQ-------ITLQGTERFWRPAAQFESARG-----VTLFPDIKIVSTFAKTEASGDMRATGTAPKSAVLEEMLHNLDFCDILVLGGDLDPRQECLELNHSELHQRHLDATN--STAGYSIYGVGSMNRYEQVLHHLRYRNWHPTSLETRRFRIKCSELNGRYTSNEFNLEVSVLHEVRVSDKEHVNHLIVQPPFLQSVHHPETRSSIQ--RSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAK-EAEMDWDDSALTITVNPMEKHEGPGNGEDETTEVEEEEEAEE-------------------GSSSSSSGSDDSEEEEEEGMGRVRHGQSGTSSQSPERSTWNTAGVINIWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4D0-1", "uniprot_id": "CSTN2_HUMAN", "id": "Q9H4D0-1", "name": "Calsyntenin-2", "aln": "----MLPGRLCWVPLLLALGVGSG--SGGGGDSRQRRLLAAKVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPHETAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAVVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPG-SGSMPLFPSIHLETCDGAVS-----SLQIVTELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKVPDGIVPKN--LTDQFTITMWMKHGPSPGV-RAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADT--FRPAEFHWKLDQICDKEWHYYVINVEFP-VVTLYMDGATYEP--------YLVTNDWPIHPSH-IAMQLTVGACWQGGEVTKPQFAQFFHGSLASLTIRPGKMESQKVISCLQACKEG------LDINSLESLGQGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLKVSSKVQCFGEDVCISIPEVDAYVMVLQAIEPR-------ITLRGTDHFWRPAAQFESARG-----VTLFPDIKIVSTFAKTEAPGDVKTT--DPKSEVLEEMLHNLDFCDILVIGGDLDPRQECLELNHSELHQRHLDATN--STAGYSIYGVGSMSRYEQVLHHIRYRNWRPASLEARRFRIKCSELNGRYTSNEFNLEVSILHEDQVSDKEHVNHLIVQPPFLQSVHHPESRSSIQ--HSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAK-ESEMDWDDSALTITVNPMEKHEGPGHGEDE-TEGEEEEEAEE-------------------EMSSSSGSDDSEEEEEEEGMGRGRHGQNG---ARQAQLEWDDSTLPY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S5G3-1", "uniprot_id": "CSTN2_DANRE", "id": "B0S5G3-1", "name": "Calsyntenin-2", "aln": "-----MKMRAITAMLLLVLSGQCG-------------ILAGKVNKHKPWIETSYHGVITENMDTVMLDPPLVALDKDAPVPYAGEICAFKIHGQEAPFEAEVLNRTSGEGVLRARGPIDCEQQKEYTFIIQAYDCGASPNGADWKKSHKAVVHIQVDDVNEFSPVFREPLYRATVTEGKIYDSILQVEAWDQDCSPQYSQICNYEIVTQDTPFAIDRNGNIRNTERLSFDKQQHYKIMVTAYDCGQKRAMESVPVHIDVKPVCKPGWQGWNKRVDYEPG-TGSKQLFPKMHLETCDGPLS-----SVRAMVELQTSHIGKGCDRETYSEKSLQKLCGAASGSTDLLPAPSTSTNWTASLLTDSGRDSDLIFRFDGRQAANIPDWVVPQN--LTDQFTIATWMKHGPSPGL-RAEKETLLCNSDKTEMNRHHYSLYVHNCRLVFLLRRDFIQLDS--FRPAEFHWRLEQICDKEWHYYVINVEFP-SVTLFVDGVTYEP--------YLVTDDWPIHPSE-IDVQLTVGACWQGGEVTTPRFTQYFRGSLSGLTIRPGKIATQKVISCLQACKEG------LDISSLESLGKGIKFHFNPAQSVLVMEADDLESINTAMTKVSYINSRQFPTPGLRKLHITTTVQCFGEDTCISIPEIKAMVMVLPPSEPR-------ITIAGVERLVWPSAQLRAPVG-----VALFKDIHIISTVTKTDATLSIARR------PGVLELMHNLDYCDVLVIGEELDPERESLEIHHSSLLGKHLDATN--STSGISIYGVDSMAHYEQAIRQVRYRNWKPGSLSERRFRLSCSELNGRYTSNEFNLEIGVVHSS--EAVEHVNHMAVQSQFMRPVHHPLVVHTVNSDHISGTPPAATVVIVMCIAALVVIVVLGIYRIHTTHQDSSKEDEEERKDPEMDWDNSNLN-SIEGTQIAEEVREEEPEEDEDEDEEDDDL-------------------AGDLSSAESEDSDEDEETNIQKG---------KVKGKLEWDPSTLPY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "R4GEC6-1", "uniprot_id": "R4GEC6_DANRE", "id": "R4GEC6-1", "name": "Calsyntenin-2", "aln": "-----MKRKLMLMLLALGLSCVR----------------AHRVNKHKPWIETSYHGVITENTDEVLLDPPLVALDKDAPVPYAGEICGFHVQGLSAPFEAVLLNGTSGEGRLRARGPIDCERHREFSFIIQAHDCGTGPQGHGQKRSHKAAVRVQVGDVNEFSPVFGQLEYHGSVTEGKVYDSILQVQASDQDCSPQYSQICNYQITSPDTAFAVDRNGNIRNTESLSFEKKSHYKIRVTALDCGQKRAMQEAIVHIHVKPICKPGWQGWRKLVDYEPG-AGSKLLFPKMHLETCEGSVS-----WIRTTVELETSGVGRGCD----SERSLQKLCGSSSGSTALLPATGGVCNWTVTLVRDSGRDSDLAYRFDGHQAAKIPDWVVPQN--LTDQFTITTWMKHGPSPGQ-RAEKETLLCNSDKTEMNRHHYSLYVHNCRLVFLLRTDYTQTDS--FRPAEFHWKLEQICDKEWHYYVLSVDFP-VVTLYVDGVTYEP--------YLVTDDWPIHSSQ-IDVQLTVGACWQGGEVSKAKFSQYFRGSLSGLTIRPGKIESQKIISCLQACKEG------LDITSLENLGQRIKFHLNPAQSVLVMEAEDLEQMNGALRKVSYINSRQFPTMGSRHLRISTAVQCFGEDVCISVPDIEVVVMVMQPSEAR-------ITITGAEHLTIP--AYDLALG-----LSLFRDLHIISTVTKRDKVTNMDHR------SSAKETAHNLDYCDILVLGEELRAGLESLELHHSALLGKHLEYAN--SSTGMSIYGVDSISHYTEVIRQVRYQSRR-AVDSVRTFRLTCSELNGRYTSDQYTLQVNILHSE--EAREHVNHLMTPPKSMQITHRTVMESNNY--FNLVVPAVSTSVVVVCIAALL-VVLLGVYQLNQTQNKDSIQTHTLA-EEQVDCEGSSLSITVNPLQNCQELQS-----AEVTEEEEDEE-------------------DCAISSTESDSDEEETDTPFTHR-----------QTKQQWGKATLHC---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V498-1", "uniprot_id": "CSTN1_DROME", "id": "Q9V498-1", "name": "Calsyntenin-1", "aln": "MTFHKTFGYGCIVLICFELLFAGVETS--------SENDDEYLTQKEIILEKSYHGLIRENETLVEITPLIKVNEE--------KICNFHILKKPYHEIPFKIELVNNLGILKARRTLNCENRKSYHFEICAIYCDGTP-------SNTANVHITVIDVNEYAPTFLEPSYVIEVDEGRLYNEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSVVAYDCAMKESAP-IMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCDISCKNEEDLRIHSSIALKTKHISFGCDRDISNCTSGQKVK-------DLLPHG---AEWTKELSYDEG--LEPIFHFDGSTGVVVPATVIDHYDFSSQPFSILTLFRHNSQVEINKHVKEHIVCSADDHKMNRHHMALFVRNCRLIFLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFENSIENRHSNPEVIDDWPLHAAHGVNTSLAIGACYQS---LENRLKHGFNGDISEVKVSLNSVLTAEDIKCGTTCAEHLLAPKPLQSNNEKSYSDNSQIKENIEMNEIYISAKNKHDIEQFMRKVQYINTKQKPTVGRRNIEVLTTLNCK-NESSLRLPPIETYIMVNEPIAPLGIDIDVVSASLETSDLTPPSYSPKIAISGTSNKLVSYQEIKLGVHILEKTCIDSVSKN------NGKLEEKNHIDSCSVVVFP-SLNPDHEDIKIDGDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNRVFKLSCAQQSSQYKSGEYTLTLTVLHPK-QTLFKSTNVLPSSLSKVNFIGNTDNETSFHRNSGSVNGNDNNQPTESKVYSYSLLHTNNVQEPKSHIHSFIHKAEGSHVTMLIILVSVFLAVLLCGVSIARLKNNQKYIEHHQPCPKISDDGLIWDDSALTITINPMQADVTSDASSESENSESEDEEALKDG--------FTHINQLEWDNSNIFQQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :.::: :*.****:* ** * : * : . :: :** *:: . :: ... * *:*: .::** ::.: * * * *. * *:.* *:: * ****::*.* : * * **::*:.**:*:* *:**:* :.::*:*:* . * .*::*.:*.*:*** **.. . :: : *.* **. * : * :.*: :*:. : . : ::* .* : * *** :*: *: . . :: *:*. :. *** . * **: *** :** * *. : ::*** .. :* :: : :: *:* ::*... : ** ::*.:*. :***** :*:*:****:**** :: : * * ***::*:: ::**:***:**:.*: . * *::**. :* * :***:*.:. : .*::***:*. :: : *.*.:: :.: ..: : : *.* :* * *: .. :. . : : * . : :...: .:: : **.***::* ** * *.:.: : ::* :: .: :* :.. :** . . : .. : * . . : : :::: . : .: * :::* *.::*: .* . * :::. . :: . .. * .: * .:: .* :.:: : * . : * *::.*:: ..:*.*.::.* : ::* : .* : :. .. . . : : .: . . : : . : . * : . . . : : :* .:..:.: : : : *. : : ", "identical_positions": 190, "similar_positions": 320, "identity": "18.34%" }, { "cls_id": "homologset.agr.MGI:1929898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKC6-1", "uniprot_id": "CEND_MOUSE", "id": "Q9JKC6-1", "name": "Cell cycle exit and neuronal differentiation protein 1", "aln": "MESRGKSASSPKPDTKVPQATAEAKATPAADGKAPLTKPVKKDTQAEKQEQAAAPGPAATKKTPAKADPVLLNNHSNLKPAPTVPAAPSSPDATSEPKGPGDGAEEDESNTGG---RGPWPCENLTPLLVAGGVAVATIALILGVAFLARKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVI4-1", "uniprot_id": "CEND_RAT", "id": "Q5FVI4-1", "name": "Cell cycle exit and neuronal differentiation protein 1", "aln": "MESRGKSASSPKPDTKVPQATAEAKATPAADGKAPLTKPVKKDAQAEKQEQPAAPGPATTKKTPAKADPVLLNNHSNLKPAPTVPAAPSSPDTTSEPKGPGDGAEEDESNTGG---RGPWPCENLTPLLVAGGVAVATIALILGVAFLARKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N111-1", "uniprot_id": "CEND_HUMAN", "id": "Q8N111-1", "name": "Cell cycle exit and neuronal differentiation protein 1", "aln": "MESRGKSASSPKPDTKVPQVTTEAKVPPAADGKAPLTKPSKKEAPAEKQQPPAAPTTAPAKKTSAKADPALLNNHSNLKPAPTVP---SSPDATPEPKGPGDGAEEDEAASGGPGGRGPWSCENFNPLLVAGGVAVAAIALILGVAFLVRKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************.*:***..************ **:: ****: .*** .*.:***.*****.*************** ****:*.*************: :** ****.***:.***********:**********.***", "identical_positions": 119, "similar_positions": 22, "identity": "78.29%" }, { "cls_id": "homologset.agr.MGI:1929899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BMT9-1", "uniprot_id": "B0BMT9_RAT", "id": "B0BMT9-1", "name": "Sulfide:quinone oxidoreductase, mitochondrial", "aln": "MAPLVAVVSSPRARLFACFLRLGTQQAGPLQLHTGACCTAKNHYEVLVLGGGSGGITMATRMKRRVGAENVAIVEPSERHFYQPIWTLVGAGAKELSSSDRSTLSVIPSGVQWIQDRVAELNPDQNCIRTDNGKEISYRYLIIALGIQLDYEKIKGLPEGFAYP--KIGSNYSVKTVEKTWKALQDFKEGNALFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTALGTIFGVKKYADALQEIIRERNVSVNYKHNLIEVRADKQEAVFENLDKPGETHVIHYEMLHVTPPMSSPDVLK-RSPVADSAGWVDVDKETLQHKKYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISLIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYTAQPLETFPFDQSKERISMYLMKADMMPFLYWNMMLRGYWGGPAFLRKLFHLGLS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R112-1", "uniprot_id": "SQOR_MOUSE", "id": "Q9R112-1", "name": "Sulfide:quinone oxidoreductase, mitochondrial", "aln": "MAPLVTVVSSPRARLFACFLRLGTQQAGPLQLHTGACCTAKNHYEVLVLGGGAGGITMATRMKRRVGAENVAIVEPSERHFYQPIWTLVGAGAKELSLSVRSTLSVIPSGVQWIQDRVAELNPDENCIRTDSGKEISYRYLIIALGIQLDYEKIKGLPEGFAYP--KIGSNYSVKTVEKTWKALQGFKEGNALFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRPKANIIFNTALGTIFGVKKYADALQEIIRERDVSVNYKHNLIEVRPDKQEAVFEILDKPGETHVIPYEMLHVTPPMSAPDVLK-RSPVADSAGWVDVDKETLQHKKYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTMCLIMKNQRPIKKYDGYTSCPLVTGYNRVILAEFDYTAQPLETFPFDQSKERITMYLMKADMMPFLYWNMMLRGYWGGPAFLRKLFHLGMN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6N5-1", "uniprot_id": "SQOR_HUMAN", "id": "Q9Y6N5-1", "name": "Sulfide:quinone oxidoreductase, mitochondrial", "aln": "MVPLVAVVSGPRAQLFACLLRLGTQQVGPLQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHP--KIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLK-TSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLETFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZF6-1", "uniprot_id": "Q9VZF6_DROME", "id": "Q9VZF6-1", "name": "Sulfide:quinone oxidoreductase, mitochondrial", "aln": "MNRRLPGTISQCQKLLLATHNHAPTAFSTRFLSTSRVNRERQECQVLVVGGGTGGCAMAAKLSSRLGSDKVVVLEPEDKHYYQPMFTLIGGGMKRLDQSHRQMADVLPTKAKWVKEKALEFDPDNNTVSTSGGKTIKYDFLIIATGLQLNYGKIPGLVEALETPDSNVCSIYSPKYVDHVYECLRRTNKGNAIFTFPNCPIKCAGAPQKIAYISEHYFRKMGRRDNVNIIYNTSLPVIFGVKHYAEALMKLIKRRNITLNVQRNLVEVRHKDNIAVFEDLAKPGVHYEETYSMLHVTPPMSTPDVVANCKKLVTPTGFVDVDQLTLQHNKYSNVFAIGDSASSPNSKTAAAAAAQSPVVFKNVMAAIEGKAPTDIYDGYSSCPIVTGYSSCILAEFDYNLTPVETFPLDQSKERYSMFFMKKELMPVLYWKLMMNGYWNGPALMRKIFSVLKFNKKQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. . . :*: . . .. .. * *. ::. :***:***:** :**:::. ::*:::*.::**.::*:***::**:*.* *.*. * * .*:*: .:*:: :. *::**:* : *...: *.* :**** *:**:* ** ** *.: * :: * ** * *::.::.*: ::***:***** *:********* *:** **** *:* :.***:**:* .*****:**:** ::*:.*::::* ::**:*** ..: **** * *** *.*********.***: . :. .:*:****: ****.:*.***.***.:. *.******.**** :: :.: ::.: * . ****:***:****. *******. *:****:****** :*::** ::**.***::*:.***.***::**:* : ", "identical_positions": 206, "similar_positions": 151, "identity": "45.08%" }, { "cls_id": "homologset.agr.MGI:1929913", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JVA1-1", "uniprot_id": "A0A0G2JVA1_RAT", "id": "A0A0G2JVA1-1", "name": "", "aln": "PVLGGCGEPQRLA--AEGL----ADHVEAAILEEDEG---LEIEEPSSLGLMVGGP-DPDLLTCGQCQMNFP-------LGDILVFIEHKKKQCGG---LGSCYDKVLDKG---SP-PPSSRSELRRVSEP------------------------VEIGIQVTPDEDD-HLLSPTKGICPKQEN-IAG-------------------------------------------------------------------------KDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEP---GPASTSLTPRLTIPPPLGPEAVAQSPLMNFLGD----------------------------------------------------------------------------------------------------------SNPFNLLRMTGPILRDHP------------------------------------------------------------GFGEGRLPG----------TPPLFSPPPRHHLDPH---RLSAEEMG------------LVAQHPSAFDRVMRLNP---------MAIDSPAMDFS-RRLRELAGNSST------------------PPPVSPGRGNPMHRLLN--PFQPSPKS----------------PFLSTPPLPPMPTG----TPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELPGD-LKAADGDFRHHESDPSLGPEPED-DEDEEEEEEELLLENESRPESSFSMDSELGRGRENGGGVPPGVAGAG-AAAAALADEKALALGKVMEDAGLGALPQYGE------KRGAFLKRAGDAG-DTG----AGGCGDAGAPGAVNGRGGAFAPGAEPFPALFPRKPAPLPSPGLGGPALHAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSS-ENGSLRFSTPPGDLLDGG-LSGRSGTASGGSTPHLGG-PGPGRP-SSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHG----EHLLTNDVKIEQAERS----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PV8-1", "uniprot_id": "BC11B_MOUSE", "id": "Q99PV8-1", "name": "B-cell lymphoma/leukemia 11B", "aln": "MSRRKQGNPQHLS--QRELITPEADHVEATILEEDEG---LEIEEPSSLGLMVGGP-DPDLLTCGQCQMNFP-------LGDILVFIEHKKKQCGG---LGPCYDKVLDKS---SP-PPSSRSELRRVSEP------------------------VEIGIQVTPDEDD-HLLSPTKGICPKQEN-IAGPCRPAQLPSMAPIAASSS-HPPTSVITSPLRALGVLPPCFPLPCCGARPISGDGTQGEGQMEAPFGCQCELSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEP---GPASTSLTPRLTIPPPLGPETVAQSPLMNFLGD----------------------------------------------------------------------------------------------------------SNPFNLLRMTGPILRDHP------------------------------------------------------------GFGEGRLPG----------TPPLFSPPPRHHLDPH---RLSAEEMG------------LVAQHPSAFDRVMRLNP---------MAIDSPAMDFS-RRLRELAGNSST------------------PPPVSPGRGNPMHRLLN--PFQPSPKS----------------PFLSTPPLPPMPAG----TPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELPGD-LKAADGDFRHHESDPSLGPEPED-DEDEEEEEEELLLENESRPESSFSMDSELGRGRENGGGVPPGVAGAG-AAAAALADEKALALGKVMEDAGLGALPQYGE------KRGAFLKRAGDTG-DAG----AVGCGDAGAPGAVNGRGGAFAPGAEPFPALFPRKPAPLPSPGLGGPALHAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSS-ENGSLRFSTPPGDLLDGG-LSGRSGTASGGSTPHLGG-PGPGRP-SSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHG----EHLLTNDVKIEQAERS----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0K0-1", "uniprot_id": "BC11B_HUMAN", "id": "Q9C0K0-1", "name": "B-cell lymphoma/leukemia 11B", "aln": "MSRRKQGNPQHLS--QRELITPEADHVEAAILEEDEG---LEIEEPSGLGLMVGGP-DPDLLTCGQCQMNFP-------LGDILVFIEHKRKQCGGS--LGACYDKALDKD---SP-PPSSRSELRKVSEP------------------------VEIGIQVTPDEDD-HLLSPTKGICPKQEN-IAGPCRPAQLPAVAPIAASS--HPHSSVITSPLRALGALPPCLPLPCCSARPVSGDGTQGEGQTEAPFGCQCQLSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEP---GPASSSLTPRLTIPPPLGPEAVAQSPLMNFLGD----------------------------------------------------------------------------------------------------------SNPFNLLRMTGPILRDHP------------------------------------------------------------GFGEGRLPG----------TPPLFSPPPRHHLDPH---RLSAEEMG------------LVAQHPSAFDRVMRLNP---------MAIDSPAMDFS-RRLRELAGNSST------------------PPPVSPGRGNPMHRLLN--PFQPSPKS----------------PFLSTPPLPPMPPGG---TPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELAGEGLKAADGDFRHHESDPSLGHEPEEEDEEEEEEEEELLLENESRPESSFSMDSELSRNRENGGGGVPGVPGAGGGAAKALADEKALVLGKVMENVGLGALPQYGELLADKQKRGAFLKRAAGGG-DAGDDDDAGGCGDAGAGGAVNGRGGGFAPGTEPFPGLFPRKPAPLPSPGLN----SAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSS-ENGSLRFSTPPGDLLDGG-LSGRSGTASGGSTPHLGG-PGPGRP-SSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHG----EHLLTNDVKIEQAERS----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q8A6-1", "uniprot_id": "A0A2R8Q8A6_DANRE", "id": "A0A2R8Q8A6-1", "name": "", "aln": "MSRRKQGNPQHLS--QREIITPEAEHVDAGLAVADLHSHPHPLLDPSMPGPLPPGLGDHDLLTCGQCQLTFP-------LGDILLFIEHKKKQCQALTSGHGCYDKMADRN---SP-SPP-RAELRKVVEP------------------------VEIGIQVTPEEEDERLLTPPKGICPKQESGLAG-------------------------------------------------------------------------RDEPSSYICTTCKQPFTNAWFLLQHAQNTHGIRIYLET---NSSNTSLTPRITIPPPIGAESIPQSPLTNFLGD----------------------------------------------------------------------------------------------------------NNPFHLLRMTGPLLREPPP-----------------------------------------------------------GFVENRIPN----------TPPFVSPPPRHHLDPHRLERLSAEEMG------------LISQHPSAFERVMRMTP---------MAMESQSMDFS-RRLRELAGNNNS------------------TPPLSPSRANPMHRLLNPNPFQPSPKS----------------PFLSTPPLPPMPPNS---TTPPQTQGKSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKSGSMTGRSDDGLSTTSSPEPGTSDVTGEGIKNRDGDFKGE------GMLQDN--EEEEEEEEEEELENESRPESNFSMDSEFCRNRENG--------------SKPPSDEKTLSLGKMVENVGLSSIQQYNNLIVDNRKRLPFSKRISEVQREVGDDDSVVGEMDQVERATVNGRN---CGSGDSFSGLFPRKPTPITSPSLSN---SSNKRIKIEKDLDIPPAPLIPSENVYSQWLVGYAASRHFIKDPFLGFTDSRQSPFATSSEHSS-ENGSLRFSTPPGDLLDGG-LSGRSGTASGGSTPHLGGGPGPGRP-SSKESRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQLGKEVYRCDICQMPFSVYSTLEKHMKKWHG----EHLMTNEVKIEQAERS----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8QLP7-1", "uniprot_id": "A0A2R8QLP7_DANRE", "id": "A0A2R8QLP7-1", "name": "", "aln": "MSRRKQGNPQHLSLTQRENLPTPADHDAGMNQCPSEG----SVSSP------AGGAGESDLLTCGQCQTNFP-------LGDILVFIEHKRRLCPGP---SSCFDKPSDCGGSGSPSPRPLRPDVCRRSGP------------------------VEVGIQVSPREEEEKRLTPARGICPKQEGVPTG-------------------------------------------------------------------------KDEPSSYICTTCKQPFTSAWFLLQHAQNTHGIRIYLDT---HPTSCSLTPRMALPPPLGADALPRSPLASFLGDG---------------------------------------------------------------------------------------------------------SNPFQLLRMGAPLLREPPH-----------------------------------------------------------GYIETRLPS----------TPPFVSPPPPRHPLER----LGPEEMG------------LLSQHPSAFERVMRMTP---------MGIHEPSMGFS-QRLRELAGNNNNGG---------------PTPPLSPNRVPPMHRLLSPTLFQHGSKAL---------------PFLPTPSQPPSIPSRGNSSSPLNQVGKAKSCEFCGKTFKFQSNLIVHRRSHTGERPYKCHLCDHACSQASKLKRHMKTHMHKSGSMG----------SSPEQGGQDSAGEGLKSCEDNGTREGID---NEEEEDDEEEEEEEEEEEEQQNGSRPDSNLSMDSELSRNRENG--------------PRTTPEDKPLATDRVTES-------QYNN--LDNHLRLPPGSRPCEGMDRDS----QAREIDRDRQPMVNGRG---CGPEDSISAMFHRKPMPISSSSLSG---SSAKRIKVEKDVELPQVPVISPENVYSQLLAGYAASRHFIREPFLGFNDSRQSPFGTPSEHSSSETGSLRFSTPPGEILEGGGMSGRSDSST--PHLHLRG-PGPGRPPSSKESRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCDLCSYACAQSSKLTRHMKTHGQFGKEVYRCDICHMPFSVYSTLEKHVKKWHG----EHLLTSEVKLEQADRA----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A499JF18-1", "uniprot_id": "A0A499JF18_DROME", "id": "A0A499JF18-1", "name": "", "aln": "MYNKMLSISEDHGFRSLSHSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQD-DGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSP---------------KTTSSGATSLVGELMDKFGLSNIAQYSE---------AYKQALQESGRKEA----AAAAAAAAAAADNNNRG----GAGAPLSDKLNGLPVAALR----------------------LRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKP--LGLGGANSLIQGPLLKK----------ESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEAXLFSGFPVPLAPPPPLQQHQPHLQQPQQQQTSRSRIMSRIF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . :. . . . : : . *** * * * ::::: . . . :. . . . . *: . :.:* :.: : . .*.. : ***.* *:*** :..** *:**.*::**.:**::. .: ** ..:. : . :. . *.. ***:**** * . * * * *. .** *** : . :: * . :: ::.* : :. *.* :***:***... . **. :: * . .. : .** .. .. . : .:. **.:*.*.*:*:.**::*:*:****:**** **. **: .** :**:.* :.. .: . .: .: : . : ::*:*:* :: . ..:*:...: :. . .. . ..: :. **.: . . . *.*. .:. : * . . *::.* * *.*: : :** . : : .: . . . * .: :: * ..: : * :. :*.****:*********************:****:**.*****************: **:**** :*.***** ******::* :. * ** :: ", "identical_positions": 179, "similar_positions": 219, "identity": "13.55%" }, { "cls_id": "homologset.agr.MGI:1929914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6V9Y3-1", "uniprot_id": "Q6V9Y3_RAT", "id": "Q6V9Y3-1", "name": "Testis-specific serine/threonine-protein kinase 3", "aln": "------------------MEDFLLSNGYQLGKTIGEGTYSKVKEA-FSKKHQR--KVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIRVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLP--KSRRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQ-KGVSFPTHLG--ISTECQDLLKRLLEPDMILRPSIEEVSWHPWLAST--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2E1-1", "uniprot_id": "TSSK3_MOUSE", "id": "Q9D2E1-1", "name": "Testis-specific serine/threonine-protein kinase 3", "aln": "------------------MEDFLLSNGYQLGKTIGEGTYSKVKEA-FSKKHQR--KVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLP--KSRRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQ-KGVSFPTHLG--ISTECQDLLKRLLEPDMILRPSIEEVSWHPWLAST--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PN8-1", "uniprot_id": "TSSK3_HUMAN", "id": "Q96PN8-1", "name": "Testis-specific serine/threonine-protein kinase 3", "aln": "------------------MEDFLLSNGYQLGKTIGEGTYSKVKEA-FSKKHQR--KVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLP--KSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQ-KGVSFPTHLS--ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VE58-1", "uniprot_id": "Q9VE58_DROME", "id": "Q9VE58-1", "name": "", "aln": "MSKYNSSAGIRQLGTRSSDVDALAQRGYNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPTDFVNKFFPRELEILTKIDHSNIIQIHSILQRGP-KIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLREILNCAWLRTVEESQTPIP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ..**::*:.****:*:.* * ::..* : ::* *:*** .* :*:::*:****:*: .:**.***:::.:*: . ** :.*. **.**::. : ..**: *.::* * ** :*::* *. .:********* **. :*:**:*****: :.:. *:*:***:*******: * *:*.* .*.**:**:*::*: *.:****:::.*:* :*: : .:* :* **::.: :. ****: * .:.*: .** :. ", "identical_positions": 111, "similar_positions": 104, "identity": "36.63%" }, { "cls_id": "homologset.agr.MGI:1929915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14686-1", "uniprot_id": "NCOA6_HUMAN", "id": "Q14686-1", "name": "Nuclear receptor coactivator 6", "aln": "MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKDFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQS--DAMDPLLSGLHIQQQSH----------PSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ-----LQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFP--------QMSNPGQFTAPQMKSLQGGP----SRVPTPLQ-----QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQ----QGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSG-QMLPQQGP-----------------------------------VNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANN---------------------DVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASG------------------------------NHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNN----TNANKPKKKKPPRKKK-------NSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQ---------------------------------------------------------QPPPP--------SQPQSQQQ--------QQQQQQ-----MMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPD--SQRMPMQQSGSVPVMVSLQGPASVPPSPDKQR-MPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYY-PQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPR-PNLNRGFDQQGLNPTTLKAIGQAPSNLTMN-PSNFAT-----PQTHKLDSVVVNSG----KQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELK--AVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIK-----PPGLTDLEVTPPVVSGEDLKKAS-VIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHP----------ELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIP---------QNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPS--HPPVQQVKELNPDEASPQVNTSADQNTLPSSQST----TMVSPLLTNSPG-SSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVP------SELISAVPTTKSNHGGIASESLAG--GLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQ---------------------SSEPKEIVEKSK-IPGRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDIT----SAVQSKRRKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JL19-1", "uniprot_id": "NCOA6_MOUSE", "id": "Q9JL19-1", "name": "Nuclear receptor coactivator 6", "aln": "MVLDDLPNFEDIYTSLCSSTMGDSEVEFDSGLEDDDTKGDSILEDSTIFVAFKGNIDDKDFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLWILAQSNNQQLRDLGILSVQIEGEGAINLALGQNRSQDVRMNGPVASGNSVRMEAGFPMASGPGLIRMTSPAAVMTPQGGNMSSSMMAPGPNPELQPRTPRPASQS--DAMDPLLSGLHIQQQSH----------PSGSLPPAHHSMQPVPVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQTRPLQQHQQQ-PQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTTNQGWKKAPLPSPMQAQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFP--------QMSNPGQFTAPQMKGLQGGP----SRVPTPLQ-----QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLSQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTAATPGNSGALQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNINNQQAGSSGVPQVTLGNMQGQPQQGPPSQLMGMHQQIVPSQGQMAQQQGTLNPQNPMILSRAQLMPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQ----QGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKAQFNSQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSG-QMLPQQGP-----------------------------------VNNSPSQVMGIQGQVLRPPGPSPHMAQQHTDPVTTANN---------------------DVNLSQMMPDVSMQQASMVPPHVQSMQGNSASG------------------------------SHFSGHGVSFNAPFGGAPNGSQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNN----TNANKPKKKKPPRKKK-------NCHQDLNTPDNRPTGLEEVDQQSLPGEQGINLDTTGPKLPDFSNRPPGYPTQPVEQRPLPQMPPQLMQHVAPPPQPPQQQPQPQLPQQQ---------------------------------------------------------QPPPP--------SQPQSQQQ--------QQQQQ------MMMMLMMQQDPKSIRLPVSQNVHPPRGPLNPD--SQRMPVQQSGNVPVMVGLQGPASVPPSPDKQR-MPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPEASGSEVPSVAGGPNNMPSHLVVSQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYY-PQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPR-PNLNRGFDQQGLNPTTLKAIGQAPSNLTITNPPNFAA-----PQAHKLDSVVVNSG----KQSNPGTTKRASPSNSRRSSPGSSRKT-TPSPGRQNSKAPKLTLASQTSTTMLQNMELPRNVLVGPTPLANPPLPGSFPNNTGLNPQNPTVPVPAMGTVLEDNKESVNIPQDSDCQNAQGRKEQVNTELK--VVPTQEAKMAVPEDQSKKDGQPLDPNKLPSVEENKNLMSPAMREAPTSLSQLLDNSGAPNVTIK-----PPGLTDLEVTPPVVSGEDLRKAS-VIPTLQDPPS-KEPSTSLSSPHSSEPCSTLARS----------ELSEVSSNAAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSSNTSAALPTHLQSALMSTVVTMPNVGNKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPATPLTTNSGLMPPSVAVVGPLHIP---------QNIKFSSAPVTPNVPSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVAP--NPSVQQVKELNPDEASPQTNTSADQSTLPPSQPT----TVVSSLLTNSPG-SSANRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGPGLEITTPGLMGTEQCSTELDSKTPTPSAPTLLKMTSSPMAPSSTSTGPILPGGALPTSVRSIVTTLVP------SELISTAPTTKGNHGGVTSEPLAG--GLVEEKVGSHPELLPSIAPSQNLAPKETPATALQGSVARPELEANAAIASGQ---------------------SCEPKEIVEKSKTLTSRRNSRTEEPTMASESVENGHRKRSSRPASASSSTKDIT----GAVQSKRRKSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JLI4-1", "uniprot_id": "NCOA6_RAT", "id": "Q9JLI4-1", "name": "Nuclear receptor coactivator 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQIMTNQMQGNKAQFNSQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSG-QMLPQQGP-----------------------------------VSNSPSQVMGIQGQVLRPPGPSPHMAQQHTDPATTANN---------------------DVNLSQMMPDVSMQQTSMVPPHVQSMQGNSASG------------------------------SHFSGHGVSFNAPFGGAPNGTQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNN----TNANKQKKKKPPRKKK-------NCHQDLNTPDSRPAGLEEVDQQSLPGEQGINLDNTGPKLPDFSNRPPGYPTQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQPQP------------------------------------------------------QPPPP--------SQPQSQQQ--------QQQQQQQQQQQMMMMLMMQQDPKSIRLPVSQNVHPPRGPLNPD--SQRVPMQQSGNVPVMVSLQGPASVPPSPDKQR-MPMPVNTPLGSNSRKMVYQESPQNSSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AA53EGP4-1", "uniprot_id": "A0AA53EGP4_DANRE", "id": "A0AA53EGP4-1", "name": "", "aln": "--MAHQPLLLGS-----PSPPDAPLSDHDSGLEDED---ENTTTDSTIYVAFKGNLHDEDFQEKLDAILNRMPDMLLLGKKKLEPERVEPWNSVRVTFNIPREAAERLRLLAQNNQQQLRDLGILSVQIEGEGAINVAVGQGQSQEVRVNGPLGAPPQMRMDAGFPMQQGQVGMRMNNPAVSMMPPGASMPGQGMVPNSAGQMQPRAPRPPSQTGNDTMDPMLSGLALQQQQQQLQHPQVGHGPLGNLGPQGHHMQAMQANRQLNPAVLQQLQQQQQQQHQQQQVQLAQLG--------------------------GARGPFNPSNQMPVPPGWNQLPSGVLQPPPVQGPMG-----PGWRKAP---PQPQIGQRPPSLASVQTPNHPPPPYPFGSQQAGQVFNAMPPHQLQQQQQQTGPNQFATPQPKGPQGAPGVVVSRAPPPLPPSSAPQGNLAAKSPGSSSSPFQQGSPGTPPMMGQ--GQLGSRP----TTPQGFRQGVGSPGRAVMGQQGNMQPGFMGIP-----QHAQLAQGGMGGMPKRMPMGFPNTSVNQNFAPGQVTTTGAG-----STPQLQNNQSMANAGVQSSASAPNHMQS-----NPLQGTGMAHHTGMPAQPPGTTSG------STMGQPQQGLQTQMMGVPQTQHQTQTVVSSQSQMAQSQAGGQTVLSRPVNAGQRGMTPPKQMMPPQGQGIMQNQNQISAGPGHQALMLQQQQQQQQQQQQQQQQQQNAMMEHIVASQMQSNKQAFGSKAQPGVIPG--QMMRGPSPNIQGNLAEFQSQMGQQQMTPQQHQQQQQQQQQQLVHLQQQQQLQQQQLQQQQLQQQQLQLQHQQPQQTQIQQQQQQLQQPHQQMVQQQSQQIPINGNPNQVLGMHGPQMRLPGNHHLVQQQLQQKQQQVMLQQQQAGQQHQHQLGDGSGSGDMGQQMVQDLQNQQQQQAMMGGSQHLQVGNGQFPGHGMSFNPQFPGQMP-IGVQCGQAGGFQVNKDVTLTSPLLVNLLQSDISASQFGPGGKQGAGGAAGNQAKPKKKKPPRKKKPKVGEGQQSADSMCGLDSLPHGMEETEMQGMGSDQGTGID-SNSKLSEFSNRP-GLPGQSGDQRVLQQMPMQFMPPQQQQQMQQMQQQQLQQQQQQMQQQQMQQQHQQIQQQQMQQQQMQMQSMQGPQGQAGTSQGPHHVQTQIHSQQSMQMQQQQPPQHLQQQLQSQPQQQQQQVQQQQQAQQQQHQHQQQQMMLMLKMQQEAKN-RMPLQQGGHMSKGLVNPNDPSQRMPVSQPGSIPLMIDLQGHGGVPPSPDKARGMPLMVNPPLAGPARRTPLTEVGQPTPPEDISGNHSLQDRGPPEIGQQSGNGNQPIISNQGSNTHLMKSVPLSVP----HQTGASPQQQPQ----QSHNIHFPSAPPTSQSSRPKTPNRASPRPYHHPLTPTNRPPSTEPSEINLSPERLNASIAGLFPPKINIPLPPRQPNLNRGFDQQGLNPTTLKAIGQAPPSLATLPVNNNSSGSNNGPQSYPAGGGLGNSGGKQDKQTGVGQAKRASPSNSRRSSPASNRKAATPSPGRQ--KGAKASLTSPHQQTMMVS---PPNMMVSPTSVVS-TTSASLPPAGPGESQQSLSSLQTLPNITDTVKDGHVLATQPEQHQGVHLKEHPAPKMASPRVPPQEPKRQESSNLVEQRTDDKQQSRTMPQHDLSSAVSPAFRDAPTSLNQLLDNAGTPTLQMKSQNTHPVGVVHVQKESPHAPLAQENQSNPVVSQSLNIGASLLTSEVEQKPKSAAVSSPNLIPGSTANLPSVSAVSSVSSNQAVLLSLTSISNPSVSSNHNLIPISNATQTVLQRPISSAQTQQNQITVFVTSNPISFATNTASVVPSAVVSKVLAVPNKNIRTPDVRQPNPNQSSP-QFITGTVFSKFQATSVPSNTNVMSQPVTMVGPLVSANIQLTPTPMSTTSAPSAPASTPMPTHSPAVSIATTQQNRTFIGQLQVQVPASQASPVSVVPPPQQPSPGGLKQDGVSDASGSKPSPVGQSPVHSGMSSPFQQLLASPPACSSPGPTTVSRRSPLPTTATMLAKSSPVQSALSKNTALTNPSNNENELKECIAVAQLGKPLEVATSQVSSVVTSETVSSVQASAPVTVPAAPIASQQTALPPKVSSPKPTPTNTSVPTSSLVSNMPPPTSASGTLQLSSVVASSSPLSSLPAVSVAASAAAVPASLTTTSGSSTSTQLSGEPQPLSVPETSAPDTTETKEAPADAPNISGQGVTTAAEQGWAKKRKTPVNLAPRDTRASTEKAK-GPSRRSSRTDKEPEE-EASDNGQRKRAARPGSASSNTGKESNTGASPTQAKRRKSK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*::.***.** *.:: *..*:** *:****:**:***:.:* .**. ** *** :.:. .* ** * : * :*.**: : . .* : .*.* :* :** . * : : ..*.** .:*.***:***. * * :.*** ** **********************.:** ..**. * * ********** :. :.: *. * *:**.: : .:** .:* :..**.:***** * * *. :** * *** *:* ** * * *** * ** ****.*** ****: **:** ***:.*. *:*:.*. * .:* :**: ***:*:.*.*.:*:*:.*** ..******* * **: **.*:.. :*: * * ... ", "identical_positions": 189, "similar_positions": 111, "identity": "8.01%" }, { "cls_id": "homologset.agr.MGI:1929938", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GVC0-1", "uniprot_id": "B2GVC0_RAT", "id": "B2GVC0-1", "name": "p53 apoptosis effector related to PMP-22", "aln": "--------------------------------------------------------------MLR------------CGLACERCRWILPLLLLSAIAFDIIALSGR-GWLQSSN---HIQTSSLWWRCFDEGGGSGSYDDGCQSLMEYAWGRAAAATLFCGFIILVICFILSFFALCGP---QMLVFLRVIGGLLALAAVFQIISLVIYPVKYTQTFRLHDNPAVNYIYNWAYGFGWAATIILIGCSFFFCCLPNYEDDLLGNAKPRYFYTSA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK95-1", "uniprot_id": "PERP_MOUSE", "id": "Q9JK95-1", "name": "p53 apoptosis effector related to PMP-22", "aln": "--------------------------------------------------------------MLR------------CGLACERCRWILPLLLLSAIAFDIIALAGR-GWLQSSN---HIQTSSLWWRCFDEGGGSGSYDDGCQSLMEYAWGRAAAATLFCGFIILCICFILSFFALCGP---QMLVFLRVIGGLLALAAIFQIISLVIYPVKYTQTFRLHDNPAVNYIYNWAYGFGWAATIILIGCSFFFCCLPNYEDDLLGAAKPRYFYPPA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FX8-1", "uniprot_id": "PERP_HUMAN", "id": "Q96FX8-1", "name": "p53 apoptosis effector related to PMP-22", "aln": "--------------------------------------------------------------MIR------------CGLACERCRWILPLLLLSAIAFDIIALAGR-GWLQSSD---HGQTSSLWWKCSQEGGGSGSYEEGCQSLMEYAWGRAAAAMLFCGFIILVICFILSFFALCGP---QMLVFLRVIGGLLALAAVFQIISLVIYPVKYTQTFTLHANPAVTYIYNWAYGFGWAATIILIGCAFFFCCLPNYEDDLLGNAKPRYFYTSA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QHT9-1", "uniprot_id": "PERP_DANRE", "id": "E9QHT9-1", "name": "p53 apoptosis effector related to PMP-22", "aln": "--------------------------------------------------------------MFR------------CGIDYTRCRWILPMLLLFAIIFDIIAIAAQSGWVEDQDA--KTHYASMWKQCR---GRNDQWD--CKSLMEFSWAQAVAALMIIGLIILIFAFIISLVALCST---VNVSLLPFIGLLLILAVIVQIIALIIYPVKFNEQIYEG-----YYDYTWAYGFGWGATILTLGCAILFCCLPRYESEITGLEKTKYIYQSG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LHK8-1", "uniprot_id": "A0A0B4LHK8_DROME", "id": "A0A0B4LHK8-1", "name": "Transmembrane protein 47", "aln": "MHQQYQQQQQQQQQGNLVGYNNKMNVLPNYTLSGMSSFDAESLPDYSEFDSESVTLDYYKESVLRPPAEKMAPTTTIETITITRPLKVIAFICGVIVVALMIMALASTDWLMASDWRQGLFVHCIEDDSVPPLPFNIQDPPGCYWTRDVGYIKATAALCIITLITDVIATVLTGLGLRTQNHNLKYKFYRIAVLVMLVSLLAVLSALIVYPVCFAGELTMAN--RRVWEFGWAYGVGWGAAIFLFGAVVLLLCDKESEEIYYKERKIVHENQMRA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : * ::.:: : :* . .*: .: .: . . . * : .: :*.** : :* :. ::: ..* : . :: :: : : :*::*** : : : : ****.**.*:*: :*. .:: * . *. * : ", "identical_positions": 26, "similar_positions": 61, "identity": "9.45%" }, { "cls_id": "homologset.agr.MGI:1929940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESS6-1", "uniprot_id": "BCAM_RAT", "id": "Q9ESS6-1", "name": "Basal cell adhesion molecule", "aln": "MEPPDARAG------LLWLTLLLSGYSGAQAELHVSVPPRVEVMRGEQIALDCTP-REHPENYVLEWLLVDASGARHRLASVEPQGSEFLGTIHNSRGRRPPYKIDSLGRLVIAEAQVGDERDYVCVVKAGAAGTSEATSSVRVFATPEATEVAPN--KGTLSVMEQFAQEIATCSSNNGNPVPRITWYQNGQRLDVPMELNSKGYMTSRTVREASGLYSLTSTLYLRLHKEDRDASFHCAAHYDLPSGQHGRLDSHTFRLTLHYPTEHVEFWVGSPSTTEGWVREGDAVQLLCQGDGSPSPEYSFFREQGNQEEQLNVNLKGNLTLEGVHRSQSGIYGCRVEDYDADEEVQLVKKLKLHVAYLDPLELSVPEEFSVFLNSSGTVVNCSARGLPAPIVRWTKDSVTVADGPILSLDSVTFDSAGTYTCEASTPTVPLLSRTQSFQLVVQGAPELKPNEIKPKSGTSWTEGDEVMLTCSARGFPEPKLTWSQRGDTTPAEPPFEGRGWMSSSLTLKVTSALSREGVSCEASNIHGKN-------------------GHVFHFGSVAPQTAQAGVAVMAVAVSVGLLLLVVAAFYCMRRKGRPGCCQRAEKGAPPAREPELSHSGSERPEHTGLLMGGPSGGGRGGNGGFGDEC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R069-1", "uniprot_id": "BCAM_MOUSE", "id": "Q9R069-1", "name": "Basal cell adhesion molecule", "aln": "MEPPDARAG------LLWLTFLLSGYSGAQAELHVSVPPRVEVMRGEQVALDCTP-REHPEHYVLEWFLVDGTGARHRLASVEPQGSEFLGTVH-SLGRVPPYEVDSRGRLVIAKVQVGDGRDYVCVVKAGAAGTSEATSSVRVFATPEDTEVSPN--KGTLSVMDQFAQEIATCSSNNGNPVPRITWYRNGQRLEVPMEVNQKGYITIRTVREASGLYSLTSTLYLRLHKDDRDANFHCAAHYDLPSGQHGRLDSHTFRLTLHYPTEHVEFWVGSPSTTEGWVREGDAVQLLCQGDGSPSPEYSFFRQQGTQEEQLNVNLKGNLTLERVHRNQSGIYGCRVEDYDADEEVQLVKKLKLHVAYLDPLELSVPEELFVFLNSSSTVVNCSARGLPTPTVRWTKDSVTLADGPMLSLQSVTFDSAGTYTCEASTPTVPLLSRTQSFQLIVQGAPELKPNEIMPKSGNSWTEGDEVMLTCSARGFPEPKLTWSQRGD-TPAEPPFEGRGWKSSSLMVKVTSALSREGVSCEASNIHGKK-------------------GHVFHFGSVAPQTAQAGVAVMAVAVSVGLLLLVVAAFYCMRRKGRPGCCRRAEKGAPPAREPELSHSGSERPEHTGLLMGGPSGGGRGGSGGFGDEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50895-1", "uniprot_id": "BCAM_HUMAN", "id": "P50895-1", "name": "Basal cell adhesion molecule", "aln": "MEPPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTP-TGTHDHYMLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPN--KGTLSVMEDSAQEIATCNSRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSPEYTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSS-AVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPDPKLSWSQLGG-SPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNK-------------------RHVFHFGTVSPQTSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAPPPGEPGLSHSGSEQPEQTGLLMGGASGGARGGSGGFGDEC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3N4-1", "uniprot_id": "A0AB13A3N4_DANRE", "id": "A0AB13A3N4-1", "name": "", "aln": "--MKRAISG----PFWICCTLLAVVLQVCLASVTVKVNPEMHVLKGDTVMLPCTYTTSAEAAVAVQWFIEFADGGRKQVAYKSSVGSDAG-------TFTDRYTIEKDMSLNISQVTVDDHKKFICQVTAGPVGTAESATEVKVFSAPEKPMVVPNPQKIFVDSSISSSAEVGKCISRNGHPEPRIIWFKDDNPLPEEKKKTEKTYMIHFLVKEASGLYTLTSMLYMHLTKADAKSVYHCIVEYTMPDNQIKQESSDNFNISLQYSTENVFFKVKN----EGPIKEGDDVVMQCETDGNPQPQFDFFK-----GEKLLEGLGGTLKKKSITREDSGTYKCEAMDYEADSKVQLHKTLNINVHYID--ITVEPEGPLVVSKGDHVELQCKAKASEAHTLQWTKDSKELSNTGVFAKESVTLADGGVYVCVGAVPSVPGLQKQVNITVNVKGQPEID----APVKGLVDKEGGMVTLNCSALGHPAPQFIWTPSGK----ESVTVKGNRVISTVTLEATAAVLKDGVICEAYNTHGRDSKNFEVKLDQAKPTPANSDRGNPDFKTVEGKQGGSSSVVIAVVVCVLLLLILVASLFFLNKKGKLGCGKKDQKEVASGGVKDNIVVEIKPSEKS---------KEEAGLLKPAEQC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : :.* . *.: :.* * :.*::*. : * ** ::*:: *.* ::* . **: * ::. * :::. *.* :.::* * **..**:*::: :.**: ** . * ** * :. . : *:..* *.**:* *:* *:::.: * : . : *: *:***** :*** **::* * * .: :** ..* :*..: : .* .*.::*:*.**:* * * . * ::*** * : *. **.*.*:: :*: * * .* *.*. : : * :** * *.. **:* ..*** *.*::.* *:* : : :.. . ::*..:. : ::***** :.: ::: .*:*: . *.*.* .: *:** *.: .: : *:* **:. * . **. * * *** *.* *:: *: * *. . *:: ::.*:*: ::*: *** * **.. .* :* : . :. .*:**.*.* ***::** :: :.:** * :: :* ... : .*:: ..* .::*", "identical_positions": 167, "similar_positions": 204, "identity": "25.61%" }, { "cls_id": "homologset.agr.MGI:1929945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKM7-1", "uniprot_id": "RAB37_MOUSE", "id": "Q9JKM7-1", "name": "Ras-related protein Rab-37", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MTGTPG------------------AATAGDG------------EAPERSPPFSPNY--DLTGKVMLLGDSGVGKTCFLIQFK-DGAFLSGTFIATVGIDSRNKVVTVDG------ARVKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITNQSSFDNIRAWLTEIHEY---AQRDVVIMLLGNKADVS-SERVIRSEDGETLAREYGVP-----FMETSAKTGMNVELAFLAIAKELKYRAGRQPDEPSFQIRDYVESQKKRSSCCSFV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0G7-1", "uniprot_id": "D4A0G7_RAT", "id": "D4A0G7-1", "name": "small monomeric GTPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MTGTPG------------------AATAGDG------------EAPERSPPFSPNY--DLTGKVMLLGDSGVGKTCFLIQFK-DGAFLSGTFIATVGIDFRNKVVTVDG------ARVKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITNQSSFDNIRAWLTEIHEY---AQRDVVIMLLGNKADVS-SERVIRSEDGETLAREYGVP-----FMETSAKTGMNVELAFLAIAKELKYRAGKQPDEPSFQIRDYVESQKKRSSCCSFA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96AX2-1", "uniprot_id": "RAB37_HUMAN", "id": "Q96AX2-1", "name": "Ras-related protein Rab-37", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MTGTPG------------------AVATRDG------------EAPERSPPCSPSY--DLTGKVMLLGDTGVGKTCFLIQFK-DGAFLSGTFIATVGIDFRNKVVTVDG------VRVKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEY---AQRDVVIMLLGNKADMS-SERVIRSEDGETLAREYGVP-----FLETSAKTGMNVELAFLAIAKELKYRAGHQADEPSFQIRDYVESQKKRSSCCSFM---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IQZ8-1", "uniprot_id": "A0AC58IQZ8_DANRE", "id": "A0AC58IQZ8-1", "name": "small monomeric GTPase", "aln": "-----------------------------------------------MVKFIR--------------LCVSAAHETAGEQLMERMT-------------------VEDLQRIFSSGLEMQEQTEAADPDSAYGSSPG------------------DTDTEDGG-----------HALTSSSSTTLVYNQELMHKTILVGDSGVGKTSLLVQFD-QGKFISGSFSATVGIGFTNKVVTVDN------MKVKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITRKSSFDNIRAWLTEIYEY---AQKDVVIMLLGNKSDMA-AERVITHEEGEKLAKEYGVP-----FMETSAKTGVNVELAFHAIARELKHRNLEQPHEPKFKIHDYIESQKQKSNCCGGIM--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP48-1", "uniprot_id": "RAB26_DROME", "id": "Q9VP48-1", "name": "Ras-related protein Rab-26", "aln": "MASTAVGLGGGEGDPGAGGPPAGSAHPDDASSMSDDVFEDAETTQARIEELRRRPFGDGSYNPPAAPASVSASITTTTTQQQQQHHNPSHHHQSSHHQPSHHHHHHHHSQLSLTGSHHYHDDAIMAPVQRSATGYPGYRPSREAMQMYAYGTDDYDDDYNDGWRSYRYD--EVDMHPAPSNAHQQPFDDTVNHKTILLGDSGVGKTSFLVKYN-TGEFRLGSFSATVGIALTNKVVVVDG------TRVKLQIWDTAGQER--FRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREY---AQEDVVIVLIGNKADCSGSERQVKREDGERLGREHNVP-----FMETSAKTGLNVELSFTAVARQLKSRGYEHGDDGKFNVHDFVRDNTKARSVCAQCRNM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38763-1", "uniprot_id": "YHI2_YEAST", "id": "P38763-1", "name": "Uncharacterized protein YHR022C", "aln": "------------------------------------------------------------------------------------------------------------MSVRLSYGASLASIPRCFDLKSSKITVMG------------------DDHSGKTSLVRSWLGSSFQISDANRYRVSDLYHKTIQFDTLVKYYRTFGVKGQLPNYAGFKAKNSGTIYESCGNFLEERLINANKSTAQRRTSIDVQVFDTNQMEVSYLSELTTLQIRQSDAIILCFDSTNDSSLASLESYICIIHHVRLECELDIPIIIACTKCDLD-SERTITHEKVLTFIQELGFSPGNLDYFETSSKFNVNVEDLFLAVLLKIE------------------KSKSDRRKLL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : ..:: .* . * :: *:: : * :::: .: :.:*::** * : .:* *::.*::* :* *..:: .:.::: * . .: *: *:: .*.* :** : *. : :* ... ::***:* .:*** * *: ::: ..:.. . ", "identical_positions": 33, "similar_positions": 75, "identity": "8.11%" }, { "cls_id": "homologset.agr.MGI:1929955", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51635-1", "uniprot_id": "AK1A1_RAT", "id": "P51635-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "------MTASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFERG------DNPFPKNADG--TVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLS--VASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQ-VFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLYPFNDPY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JII6-1", "uniprot_id": "AK1A1_MOUSE", "id": "Q9JII6-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "------MTASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG------DNPFPKNADG--TVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLS--VASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQ-VFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLYPFNDPY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14550-1", "uniprot_id": "AK1A1_HUMAN", "id": "P14550-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "------MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG------DNPFPKNADG--TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS--VASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIK-VFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568L5-1", "uniprot_id": "A1A1B_DANRE", "id": "Q568L5-1", "name": "Aldo-keto reductase family 1 member A1-B", "aln": "-------MNDFAVLSTGRKMPLLGLGTWKSEPGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKLWNTKHHPDDVEPSLLKTLKDLKLEYLDLYLIHWPYAFQRG------DTPFPRKEDG--TLLYDDIDYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILS--VASIKPTVLQVESHPYLAQVELLSHCRDRGLVMTAYSPLGSPDRAWKHPDEPVLLEEPAIAALAKKYNKTPAQIIIRWQTQRGVVTIPKSITQSRIKENIQ-VFDFTLESEEMSQVTALHRGWRYIVPTITVDGKSVPRDAGHPHYPFNDPY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AZW2-1", "uniprot_id": "A1A1A_DANRE", "id": "Q6AZW2-1", "name": "Aldo-keto reductase family 1 member A1-A", "aln": "-------MTATITLSTGQRMPTVGLGTWKSAPGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAFGRG------DELIPRHPDG--TIQYDDTHYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILS--IAKHKPVVNQVECHPYLVQAELVSHCWSRNLTVTAYSPLGSPDRPWVTPGEALLLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVVCIPKSVTPSRIKQNIE-VFDFKLSDEDMRLIESFNRNERFIIPTVIKDGQKIWRDAKHPHFPFIEPY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTL0-1", "uniprot_id": "Q9VTL0_DROME", "id": "Q9VTL0-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "------MSTPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEG-VVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS-----DNLYPTCPDTN-KAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLS--VAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMT---------MKAAYGHPHHPFEPKAKVDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "id": "Q12458-1", "name": "Aldehyde reductase YPR1", "aln": "MPATLKNSSATLKLNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIKDS-----GVPREEIFITTKLWGTEQR--DPEAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSAN--------APLLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFK---IFTLPEDDFKTISNLSKVH----------GTKRVVDMKWGSFPIFQ------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "id": "P14065-1", "name": "Glycerol 2-dehydrogenase (NADP(+))", "aln": "MPATLHDSTKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDS-----GVPREEIFVTTKLWCTQHH--EPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTD--------APLLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRK---IFTLSTEDFEAINNISKEK----------GEKRVVHPNWSPFEVFK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* :* :*:***:* :: *:. ****:* * * ** ::* *: : : *:::*:*:*** *.:: . : :: * :.*::***:*** * * . .: ** :: * * :*:*:***. .::. :* . *.. *:* ** * * *: * . : : *** :** . **.. : :*:. ..:::: : * : :.:*:. .:: * : * : ::: : : . . ", "identical_positions": 68, "similar_positions": 87, "identity": "19.65%" }, { "cls_id": "homologset.agr.MGI:1929977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZK6-1", "uniprot_id": "D3ZZK6_RAT", "id": "D3ZZK6-1", "name": "", "aln": "MRRPRRLKSDWKLS----TEPREPGARPALLQAMMILRFIALALVTGHVGGETRIIKGYECRPHSQPWQVALFQKTRLLCGATLIAPKWLLTAAHCRKP-------HYVILLGEHN-LEKTDGCEQRRMATESFPHPGFNNSLPNKDHRNDIMLVKMSSPAF----ITRAVRPLTLSSLCVTAGTSCLISGWGTTSSPQLRLPHSLRCANVSIIGHKECERAYP---GNITDTMLCASVRKEGKDSCQGDSGGPLVCN-GSLQGIISWGQDPCAVTRKPGVYTKVCKYFDWIHEVMRNN-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYN3-1", "uniprot_id": "KLK11_MOUSE", "id": "Q9QYN3-1", "name": "Kallikrein-11", "aln": "MRR---LKSDWKLS----TETREPGARPALLQARMILRLIALALVTGHVGGETRIIKGYECRPHSQPWQVALFQKTRLLCGATLIAPKWLLTAAHCRKP-------HYVILLGEHN-LEKTDGCEQRRMATESFPHPDFNNSLPNKDHRNDIMLVKMSSPVF----FTRAVQPLTLSPHCVAAGTSCLISGWGTTSSPQLRLPHSLRCANVSIIEHKECEKAYP---GNITDTMLCASVRKEGKDSCQGDSGGPLVCN-GSLQGIISWGQDPCAVTRKPGVYTKVCKYFNWIHEVMRNN-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBX7-2", "uniprot_id": "KLK11_HUMAN", "id": "Q9UBX7-2", "name": "Kallikrein-11", "aln": "MQR-LRWLRDWKSSGRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKP-------RYIVHLGQHN-LQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS----ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYP---GNITDTMVCASVQEGGKDSCQGDSGGPLVCN-QSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLF5-1", "uniprot_id": "Q9VLF5_DROME", "id": "Q9VLF5-1", "name": "trypsin", "aln": "MRSSIGLTGMAKTI---LHLFIGGILLVN-----LSLGATVR-----RPRLDGRIVGGQVANIKDIPYQVS-LQRSYHFCGGSLIAQGWVLTAAHCTEG-------SAILLSKVRIGSSRTSVGGQLVGIKRVHRHPKFD--AYTIDFDFSLLELEEYSAKN----VTQAFVGLPEQDADIADGTPVLVSGWGNTQS-AQETSAVLRSVTVPKVSQTQCTEAYGNF-GSITDRMLCAGLPEGGKDACQGDSGGPLAAD-GVLWGVVSWGYG-CARPNYPGVYSRVSAVRDWISSVSGI--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQ10-1", "uniprot_id": "Q8IQ10_DROME", "id": "Q8IQ10-1", "name": "trypsin", "aln": "-MLALRLFVLLQCS---LLVLAGVCLIPQPVKRQRSLEDVIKNPWKLSPRLDGRIVGGHRINITDAPHQVS-LQTSSHICGGSIISEEWILTAAHCTYG-------KTADRLKVRLGTSEFARSGQLLRVQKIVQHAQFN--YTNVDYDFSLLQLAHPIKFD----ETKKAVKLPESQMKYMDGEACFVSGWGNTQN-LLESREWLRQVEVPLVNQELCSEKYKQY-GGVTERMICAGFLEGGKDACQGDSGGPMVSESGELVGVVSWGYG-CAKPDYPGVYSRVSFARDWIKEHSGV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W586-1", "uniprot_id": "Q9W586_DROME", "id": "Q9W586-1", "name": "trypsin", "aln": "----MTQFGLHGCS----YILFWFLLACAAADLQENQQSRIINGSVAKADETRHLVSIRLLRHDNN-------FGSGHICGGALIAPRKVLTAAHCLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDDVGILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTEQ--SSLSNILLTANVSTIRHQTCRMIYR---SGLLPGMMCAGRLQGGTDSCQGDSGGPLVHE-GRLVGVVSWGYG-CAEPGLPGVYVDVEYYRQWIEGRSGAPHSRLATGLFLLLLLPLLMRCSGSWL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS86-1", "uniprot_id": "Q9VS86_DROME", "id": "Q9VS86-1", "name": "Peptidase S1 domain-containing protein", "aln": "------------------------------MNILALILLLICGHKTSALSPQERIVGGVEVPIHLTPWLASITVHGNYSCSSALITSLWLVTAGHCVQY---------PDSYSVRAGSTFTDGGGQRRNVVSVILHPDFN--LRTLENDIALLKLDKSFTLG----GNIQVVKLPLPSLNILP-RTLLVAGWGNPDATDSESEPRLRGTVVKVINQRLCQRLYSHLHRPITDDMVCAAG--AGRDHCYGDSGAPLVHR-GSSYGIVSFAHG-CADPHFPGVYTRLANYVTWIFNVLENDRKINMTYKN----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: *..::*: ::**.** . . :: : : ::*** .. * . : : : * * : *:**. * * * ****.*:. *::*:. . ** . **** : ** ", "identical_positions": 33, "similar_positions": 38, "identity": "10.19%" }, { "cls_id": "homologset.agr.MGI:1929988", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPW2-1", "uniprot_id": "KLF15_MOUSE", "id": "Q9EPW2-1", "name": "Krueppel-like factor 15", "aln": "MVDHLLPVDETFSSPKCSVGYLGDRLASRQPYHMLPSPISEDDSDVSSPCSCASPDSQAFCSCYSAGPGPEAQGSILDFLLSRATLGSGGGSGG-IGDSSGPVTWGSWRRASVPVKEEHFCFPEFLSGDTDDVSRPFQPTLEEIEEFLEENMEAEVKEAPENGSRDLETCSQLSAGSHRSHLHPESAGRERCTPPPGGTSGGGAQSAGEGPAHDGPVPVLLQIQPVAVKQEAGTGPASPGQAPESVKVAQLLVNIQGQTFALLPQVVPSSNLNLPSKFVRIAPVPIAAKPIGSGSLGPGPAGLLVGQKFPKNPAAELLKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRAVRAIN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIH9-1", "uniprot_id": "KLF15_HUMAN", "id": "Q9UIH9-1", "name": "Krueppel-like factor 15", "aln": "MVDHLLPVDENFSSPKCPVGYLGDRLVGRRAYHMLPSPVSEDDSDASSPCSCSSPDSQALCSCYGGGLGTESQDSILDFLLSQATLGSGGGSGSSIGASSGPVAWGPWRRAAAPVKGEHFCLPEFPLGDPDDVPRPFQPTLEEIEEFLEENMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGASAGGAQGPGGGPTPDGPIPVLLQIQPVPVKQESGTGPASPGQAPENVKVAQLLVNIQGQTFALVPQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRSVRSVN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********.******.********..*:.*******:******.******:******:****..* *.*:*.********:**********. ** *****:**.****:.*** ****:*** **.***.*******************. ***.**..*:**::*******.*:***** *:*****:*****:*.****..* **: ***:*********.****:************.*****************:***************************:***.*********:************:********************************************************************************************:**::*", "identical_positions": 354, "similar_positions": 52, "identity": "85.1%" }, { "cls_id": "homologset.agr.MGI:1929996", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925B3-1", "uniprot_id": "TRPM7_RAT", "id": "Q925B3-1", "name": "Transient receptor potential cation channel subfamily M member 7", "aln": "-----------------------------------------------------------------------------MSQKSWIESTLTK------RECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLV---KQHACFTASLATKYSDVKLGEHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEIILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGN--LPDAAEPDIISTIKKTFNFGQSEAVHLFQTMMECMKKKELITVFHIGSE---DHQDIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVSFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLIRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNASSSTPQLRKSHETFGNRADKKEKMRHNHFIKTAQPYRPKMDASMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILMLEYKTKAEMSHIPQSQDAHQMTMEDSENNFHNITEEIPMEVFKEVKILDSSEGKN--------------------EMEIHIKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKIREVFMSEAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSALPTICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRK--KDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFDEKDDKFNSGSEERIRVTFERVEQMSIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSIS---KHLAQNLIDDVPVRP-MWKKPSVVNTLSSSLPQGDRESNNPFLCNIFMKDEKDPQYNLFGQDLPVIPQRKEFNIPEAGSSCGALFPSAVSPPELRQRRHGVEMLKIFNKNQKLGSSPNSSPHMS-SPPTKFSVSTPSQPSCKSHLESTTKD------------------------------PEPIFYKAAEGDNIEFGAFVGHRDSMDLQRFKETSNKIRELLSNDTPENTLKHVG-AAGYN------------------------------ECHKTPTSLHSEQ-ESCSRRASTEDSPDVDSRAALLPDWLRDRPTNREMPSE-----GGTLNGLASPFKPVLDTNYYYS-AVERNNLMRLSQSIPFVPVPPRGEP-------------------------VTVYRLEESSPSILNNSMSSWSQLG----LCAKIEFLSKEEMGGGLRRAVKVLCTWSEHDVLRSGHLYIIKSFLPEVINTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDESSDLNLQAGNSTKESEATNSVRLML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923J1-1", "uniprot_id": "TRPM7_MOUSE", "id": "Q923J1-1", "name": "Transient receptor potential cation channel subfamily M member 7", "aln": "-----------------------------------------------------------------------------MSQKSWIESTLTK------RECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLV---KQHACFTASLAMKYSDVKLGEHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEIILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGN--LPDAAEPDIISTIKKTFNFGQSEAVHLFQTMMECMKKKELITVFHIGSE---DHQDIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVSFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLIRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHETFGNRADKKEKMRHNHFIKTAQPYRPKMDASMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILMLEYKTKAEMSHIPQSQDAHQMTMEDSENNFHNITEEIPMEVFKEVKILDSSDGKN--------------------EMEIHIKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVKMEQLPSVQEWIVIAYIFTYAIEKVREVFMSEAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCVCKRRK--KDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFDEKDDKFNSGSEERIRVTFERVEQMSIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSIS---KHLAQNLIDDVPVRP-LWKKPSAVNTLSSSLPQGDRESNNPFLCNIFMKDEKDPQYNLFGQDLPVIPQRKEFNIPEAGSSCGALFPSAVSPPELRQRRHGVEMLKIFNKNQKLGSSPNSSPHMS-SPPTKFSVSTPSQPSCKSHLESTTKD------------------------------QEPIFYKAAEGDNIEFGAFVGHRDSMDLQRFKETSNKIRELLSNDTPENTLKHVG-AAGYS------------------------------ECCKTSTSLHSVQAESCSRRASTEDSPEVDSKAALLPDWLRDRPSNREMPSE-----GGTLNGLASPFKPVLDTNYYYS-AVERNNLMRLSQSIPFVPVPPRGEP-------------------------VTVYRLEESSPSILNNSMSSWSQLG----LCAKIEFLSKEEMGGGLRRAVKVLCTWSEHDILKSGHLYIIKSFLPEVINTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDESSDLNLQSGNSTKESEATNSVRLML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QT4-1", "uniprot_id": "TRPM7_HUMAN", "id": "Q96QT4-1", "name": "Transient receptor potential cation channel subfamily M member 7", "aln": "-----------------------------------------------------------------------------MSQKSWIESTLTK------RECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLV---KQHACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGN--LPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSD---EHQDIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKN--------------------EMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRK--KDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSIS---KHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNKNQKLGSSSTSIPHLS-SPPTKFFVSTPSQPSCKSHLETGTKD------------------------------QETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFT------------------------------DCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSE-----EGTLNGLTSPFKPAMDTNYYYS-AVERNNLMRLSQSIPFTPVPPRGEP-------------------------VTVYRLEESSPNILNNSMSSWSQLG----LCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYE2-1", "uniprot_id": "TRPCG_DROME", "id": "A8DYE2-1", "name": "Transient receptor potential cation channel trpm", "aln": "MVVTDSPLAPHKYVRRISKDFSTVRRYSNTPAVVVGSFRASTSAFIAAESAAHLPTCSSPTTRTPVSTPRGIRRRQRMRKRSSVSSTLSKVLILNVRDLLKAHAGSEPLKEHQPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPAN-TLGYILRDVRP-HIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLS-------------LVTGLLPFT------------------------SEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF----------RENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRKAKGLEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENIQTATVQNIEFRLRKMEESSEQILSHLAVIHRFMSTHTAGADDLRGSTINIPGEMQRMRTISISDTEGGSGPGGNGGGGGGGGAIVPLGLGAGLNLNSLQVTTRRRFNRSLTEVRPDAYIFDEGTHFEVVPLPEEPDEVVKSREALNEQVVRKASMQSEADSDIYIPVSQRPSTCETVKRTPYVTVRQDTGASTESKDTLTPMGNNDDDQTLVGGDNSDDATPDINFEAARHRALRQRTVSLCRRNSETYSLTGADINRSHISLNQLASLSRRQMSLTQSEPDSDKDAPIAQGSAHPGKSVLHAKPSRNILLKLHSEYTSITDELESVCHMIASPTVSLPSNKASLDRPKTEMSRAEAAALLEKKHLKECEENDYMILEGLIESRGSIDASAQGFEIGVSIDYSHRYPLRRETAVELSPSKPSVDGDLMGGGEGGGAGGGDSSDTSGAGSCGAMVGISSGFQLKNERPWQRNSSMEQQTYPSPLVPTRATSDFLNPPYEGRLFKKSSESLQKNSSTETDYSAHPYRFIKQSSNETNTSLTGSYNVDTPSLTAEPSLDAGDSHSATGISISVGAVGGTATARYQPIRTASVGAADGRRLREESSS---SLDLSSSGPVTMQAAPAPPVRPMLLKKQFSVDQGKPSQTAAEAVPQTPEAAQAGQAKLISTLKPQPFASKLGMNVLKESSSSTDESVGSSAKSSNPALSIPQISTHLVQDEIAKLSSNIKSSTESEKDPPFNETMC--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::* :.***:* *: : ..*: :. * . * :: : * ::: *:.: .. * :. * . ... : * ***. .******.*:****:*. :*:*****:**:**:::**: ***::*****:*:*:** :*:*:.::*: : ***:*** ******:***.****:*:***** ...: : :: :*******::*..::*:*:: .* ::: .* *** **** *::*:***:** .*****: ***:*** *.: ::*. ...***.*::***.*.* :****: :*********:*:********::** :.:* : : :: . :*.**:***:.* .:: :*:* :::* :.*:*****:* .. : *::* :*****:*. : *. :** *:*:*:*****:..:*****:* *:*::**::** **: *****:******:***************:**:* * :::***: ::* ** ** ******: ****:**. ***::** ** .: .. .: *::*: * . :::. ::. *: .* * :*:******* * *** ** ::* ****::**:**:**:*::**:** :.** : ***:.*:::* . . :**: *:*** * :*** **:.***.:**.***::. *.::**.*:*::*:*:*** *. ***: :****.: :* * *::*:* *:.::**::: * . : .::: .. : : . : *:. :* * : : : * :.:*** ** ***.*** :::**: **::::*.***:***:* *** **** * .:**:**:: **. :.:*:.** : :* .* *** *.:*:.:** ::.: **:***:: *:**:*:*::*.**: ** * *:**** **:*:**::*:**:****.*:*****:: *:*:* *::.*:**:*::***:* :** ..:. * .* *:**: ::**:: *:::*****.***:: :*:::*: ** :**: .:* *::*******:* *.*: **: :: * : : .:* **** ::* ::*:****:*** :*.*:: ::..::**:: * **** *. :*:::.:: * . ::*.:: :: :::: * :. * .: ::.:: ..: :.*. ::: *.* . : . . .: :* * . * :: : : . . . * . : ..*:. .. . :. * : * * .:: : :.. ..: :. :* ... .* :....*. * . :: ..: :.:. .: . :*. :.*::: . *.: * ..:. .:. :. :.. * . . * :. * .. : .:: * * . *:: * * * *:::. :. *: :. :* : .:.*:. :.** * * . * : ::*::. * *.**.. : . *. :**. * :::: : . *. : *.* * : . .: ** : : . * . : ::. * .: . . . :.*: : :*. **. : ...* : : . : : : :. :*: :.* :. ... :*: : . .::** :.:*: :. . . . . . ::: : . *::....:::. . *.. ", "identical_positions": 591, "similar_positions": 659, "identity": "28.45%" }, { "cls_id": "homologset.agr.MGI:1930001", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A287-1", "uniprot_id": "D4A287_RAT", "id": "D4A287-1", "name": "Class E basic helix-loop-helix protein 22", "aln": "MERGLHLGAAAASEDDLFLHKSLGASAAKRLEAAFRSTPPGMDLSLAPPTRERPASSSS-PLGCFEPADPEGAGLLLPPPGGGGG-----ASGG--GVSVPGLLVGSAGVGGEPSLSSLPAGAALCLKYGESAGRGSVAESSGGEQSPDDDSDGRCELVLRAGGPDPRASPGAGSGGAKVAEGCSNAHLHGGSGLPPG--------GPTSGSG-GNGGGGS------------SKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCPEKCALFNSVSSSLCKQCTEKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6A8-1", "uniprot_id": "BHE22_MOUSE", "id": "Q8C6A8-1", "name": "Class E basic helix-loop-helix protein 22", "aln": "MERGLHLGAAAASEDDLFLHKSLGTSAAKRLEAAFRSTPPGMDLSLAPPTRERPASSSS-PLGCFEPADPEGAGLRLPPPGGGGG-----ASGGGGGVSVPGLLVGSAGVGGEPSLSSLPAGAALCLKYGESAGRGSVAESSGGEQSPDDDSDGLCELVLRAGGPDPRASPRAGGGSAKVAEGCSNAHLHGGSGLPPG--------GPTSGGGSGGGGGGS------------SKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCPEKCALFNSVSSSLCKQCTEKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFJ8-1", "uniprot_id": "BHE22_HUMAN", "id": "Q8NFJ8-1", "name": "Class E basic helix-loop-helix protein 22", "aln": "MERGMHLGAAAAGEDDLFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCPEKCALFNSVSSSLCKQCTEKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R9F5-1", "uniprot_id": "F1R9F5_DANRE", "id": "F1R9F5-1", "name": "Class E basic helix-loop-helix protein 22", "aln": "MDRRINLGGD-------IFHKTLSAVSSKKMDS-FRPT-AGIDLSAR--------DSQS-PISCFEQNDPD-----PVQPGGRAG-----------------------------TLG-LPTG-SLCVKYGESANRTSGAESSGGEQSPDDDSDERCEMMLMTDG--RTTVPGAKS--------------EGG------------------------------------------KKNKEQKMLRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLP-------ATTALTPGLSAYEQPAGYPFPAGVA-ASSCPDKCALFNNVTSSLCKQCTDKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJC1-1", "uniprot_id": "Q9VJC1_DROME", "id": "Q9VJC1-1", "name": "", "aln": "MDP-----------------SNLAFGFPGLPNHGHMPIPPTANMLGG----QHPAPTASPPQSVPGRRTP---------------------------------------------LGSVGLGGFYAQGMGMSQ-QPPTDENKPGPSAPEKPLSPTAAAIAAIAISGGTTTVAVSSGG------------ASGSGSNSG-----------------------------------KQKNRQGKTVRLNINARERRRMHDLNDALDELRSVIPYAHSPSVRKLSKIATLLLAKNYILMQQNALEELRRLLAYIQS-----------------TTGAAPLDLGAFPAAA--KLQALLQGPHNEPP-------TSSS---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ..*. . : . . . :: : * * . * *. : * . * * : . *.. * .:*:. . . : : . . .* :*.:: * :***********************:***************************** :****:***:**::. :: * *.*: .* : * : . . * .:** ", "identical_positions": 84, "similar_positions": 54, "identity": "22.05%" }, { "cls_id": "homologset.agr.MGI:1930003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKE1-1", "uniprot_id": "TREM3_MOUSE", "id": "Q9JKE1-1", "name": "Triggering receptor expressed on myeloid cells 3", "aln": "-----------------------------------------------------MSPLLLWLGLMLCVSGLQAGDEEEHKCFLEGENLTLTCPYNIMLYSLSLKAWQRVRSHGSPETLVLTNTRKADFNVARAGKYLLEDYPTESVVKVTVTGLQRQDVGLYQCVVYLSPDNVIILRQRIRLAWCQGK--PVMVIVLTCGFILNKGLVFSVLFVFLCKAGPKVLQPSKTSKVQGVSEKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJA7-1", "uniprot_id": "D3ZJA7_RAT", "id": "D3ZJA7-1", "name": "", "aln": "MGQRSGTCGDRSQSTSKWSSMLPQLCRLASCLWPLAVSTPRKVLHTEEAGTWGMSPLLLWLGLLLCVSGLKDGDEEEQKCFLKGENLTLTCPYNIMLHSSSLKAWQRVRSHGSPETLVITNTRKPDFNVARAGRYLLEDYPTESIVKVTMTELQKQDVGLYQCVIYLSPNNVVILYHRIRLVWCQEQWVTVMVIVLTCGFILNKGLVFSVLFVLLCKAGPKVLQPSKTSKVQGASEKQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **********:******: *****:****:**************:* ******************:*****.********:**********:****:* **:*********:****:**:** :****.*** : .***********************:*******************.****", "identical_positions": 158, "similar_positions": 20, "identity": "66.39%" }, { "cls_id": "homologset.agr.MGI:1930004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAU9-1", "uniprot_id": "D4AAU9_RAT", "id": "D4AAU9-1", "name": "", "aln": "MSEGALSTPTMASLLSPSLPLLAALALTLALTVNPAASTNAKGKQVAVGGVEPADPNDKEVQKVINFAVKTYNDMNN-DLYLSRPIRVMSASQQVVSGKNFYLKIELGQTMCTKAQSDLADCPFNEQPDQQKRAVCNFQINVEPWLNKISLTNFKCYNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM84-1", "uniprot_id": "CSTD_MOUSE", "id": "Q9JM84-1", "name": "Cystatin-D", "aln": "----------MASLLSPSMPVLAAVALTLTLAVIPEASTNAEAKQVVLGGVEPADPKDKEVQKVVKFAVRTYNDMDN-DLYLSKPIRLMSASQQVVAGKNYYLKIELGRTTCTKTESNLVDCPFNEQPDQQKRVICNFQINVAPWLNKMSMTNFNCYNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28325-1", "uniprot_id": "CYTD_HUMAN", "id": "P28325-1", "name": "Cystatin-D", "aln": "----------------MMWPMHTPLLLLTALMVAVAGSASAQSR-TLAGGIHATDLNDKSVQCALDFAISEYNKVINKDEYYSRPLQVMAAYQQIVGGVNYYFNVKFGRTTCTKSQPNLDNCPFNDQPKLKEEEFCSFQINEVPWEDKISILNYKCRKV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :.: * :* * .*:.*:.: . **:..:* :**.** .:.**: **.: * * * *:*:::*:* **:*.* *:*:::::*:* ***::.:* :****:**. ::. .*.**** ** :*:*: *::* :.", "identical_positions": 53, "similar_positions": 57, "identity": "33.33%" }, { "cls_id": "homologset.agr.MGI:1930005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABU7-1", "uniprot_id": "D4ABU7_RAT", "id": "D4ABU7-1", "name": "Triggering receptor expressed on myeloid cells 1", "aln": "MRKAGLWGLLLVFFVSEVKAAIVPEEERYDLVEGQTLTVNCPFNIMKYARSRKAWQRLSAGKEPLTLVVTERSSTTSSEVRVGKYTLKDDPTEAMLFVQMTDLQVTDSGLYRCVIYHPPNDPVLLFHPVRLVVTKGSSGVSVPDIIPTTKPTEVPVLITTKHS-------TPTRSLPKSTAVVSSPDPGVTINNGTDPTSVSTYNVVVPVVCGLLIKTLIFFVLFVVTKRSFG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKE2-1", "uniprot_id": "TREM1_MOUSE", "id": "Q9JKE2-1", "name": "Triggering receptor expressed on myeloid cells 1", "aln": "MRKAGLWGLLCVFFVSEVKAAIVLEEERYDLVEGQTLTVKCPFNIMKYANSQKAWQRLPDGKEPLTLVVTQRPFTRPSEVHMGKFTLKHDPSEAMLQVQMTDLQVTDSGLYRCVIYHPPNDPVVLFHPVRLVVTKGSSDVFTPVIIPITRLTERPILITTKYSPSDT---TTTRSLPKPTAVVSSPGLGVTIINGTDADSVSTSSVTISVICGLLSKSLVFIILFIVTKRTFG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP99-1", "uniprot_id": "TREM1_HUMAN", "id": "Q9NP99-1", "name": "Triggering receptor expressed on myeloid cells 1", "aln": "MRKTRLWGLLWMLFVSELRAATKLTEEKYELKEGQTLDVKCDYTLEKFASSQKAWQIIRDGEMPKTLACTERPSKNSHPVQVGRIILEDYHDHGLLRVRMVNLQVEDSGLYQCVIYQPPKEPHMLFDRIRLVVTKGFSGTPGSNENSTQNVYKIPPTTTKALCPLYTSPRTVTQAPPKSTADVSTPDSEINLTNVTDIIRVPVFNIVILLAGGFLSKSLVFSVLFAVTLRSFVP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ***** ::****::** **:*:* ***** *:* :.: *:* *:**** : *: * **. *:*. . . *::*: *:. ..:* *:*.:*** *****:****:**::* :**. :******* *.. . . . : * *. . * *:: **.** **:*. :.: * ** *.. .:.: : *:* *:*:* :** ** *:* ", "identical_positions": 95, "similar_positions": 66, "identity": "40.6%" }, { "cls_id": "homologset.agr.MGI:1930008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYH7-1", "uniprot_id": "GHRL_RAT", "id": "Q9QYH7-1", "name": "Appetite-regulating hormone", "aln": "MVSSATICSLLLLSMLWMDMAMA----GSSFLSPEHQKAQQRKESKKPPAKLQPRALEGWLHPEDRGQAEEAEEELEIRFNAPFDVGIKLSGAQYQQHGRALGKFLQDILWEEVKEAPANK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQX0-1", "uniprot_id": "GHRL_MOUSE", "id": "Q9EQX0-1", "name": "Appetite-regulating hormone", "aln": "MLSSGTICSLLLLSMLWMDMAMA----GSSFLSPEHQKAQQRKESKKPPAKLQPRALEGWLHPEDRGQAEETEEELEIRFNAPFDVGIKLSGAQYQQHGRALGKFLQDILWEEVKEAPADK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBU3-1", "uniprot_id": "GHRL_HUMAN", "id": "Q9UBU3-1", "name": "Appetite-regulating hormone", "aln": "MPSPGTVCSLLLLGMLWLDLAMA----GSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPEDGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKX9-1", "uniprot_id": "F1QKX9_DANRE", "id": "F1QKX9-1", "name": "", "aln": "MPLRCRASSMFLLLCVSLSLCLESVSGGTSFLSPTQKPQGRR------PPRVGRREAADPEIP-------VIKEDDRFMMSAPFELSMSLSEAEYEKYGPVLQNLLENLLRDSSFEF----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*::** : :.:.: *:***** :: :* *.:: * . * ::: .. :.***::.:.** .:*:::. .* ::*:::* :. * ", "identical_positions": 24, "similar_positions": 43, "identity": "19.83%" }, { "cls_id": "homologset.agr.MGI:1930009", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXZ3-1", "uniprot_id": "P2R3C_RAT", "id": "Q6AXZ3-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "------MDWKDVLRRRLASPNSDPKRKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPMIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRVSIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNE-NSADLDDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK24-1", "uniprot_id": "P2R3C_MOUSE", "id": "Q9JK24-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "------MDWKDVLRRRLASPNTDPKRKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPMIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNE-NSADLDDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969Q6-1", "uniprot_id": "P2R3C_HUMAN", "id": "Q969Q6-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "------MDWKEVLRRRLATPNTCPNKKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQTPPMIGEEAMINYENFLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDSE-NSADLDDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803V3-1", "uniprot_id": "P2R3C_DANRE", "id": "Q803V3-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "MANDITAHWKDLLRKRLASLKPD---GRTEEEKKAEESELFSKYYTEWKGGEKGEDDSFKHIPRFYYRLPAEDEVLMQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQVPPTTGDEAMISYESFLKVGEKAGTKCKLFFTARVYAKLLHNDPYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLHTGKIKIQDILACSFLDDLLELRDEELSKESQESNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTGTLTSVFLDRVYQACLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDMENKGYLNVFALNYFFRAIQEQMKIHGQEPVSFQDVKDEIFDMVKPKDPYKITLQDLVNSGQGDTVSSILIDLNGFWTYENREVLVANDTDSNAADLDDT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**::**:***: :. ::*:* * ** :**:***:*****.*. :: :* ***************:************************************ ** *:****.**.*********.*** ****:*:*****.*.***:******************************************************************************:********************************:************************************.*:*.******:* *************************************:*********:********** ******:******************** **:****:**.*****::***************.*****.: *:******", "identical_positions": 387, "similar_positions": 46, "identity": "84.13%" }, { "cls_id": "homologset.agr.MGI:1930016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLU4-1", "uniprot_id": "SHAN3_RAT", "id": "Q9JLU4-1", "name": "SH3 and multiple ankyrin repeat domains protein 3", "aln": "--------------------------------------------------------------------------------------MDGPGASAVVVRVGIPDLQQTKCLRLDPTAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQDYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLRNGGAHLDFRTRDGLTAVHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRR-----------------LAGPSGLASPRPLQRSASDINL----------KGD-QPAASPGPTLRSLP-------HQLLLQRLQEE------KDRDRDGEQENDISGPSAGRGGHSKISPSGPGGSGP-----APGPGPASPAPPAPPPRGPKRK---LYSAVPGRKFIAVKAHSPQGEGEIPLHRGEAVK------------------------------------------------VLSIGEGGFWEGTVKG--RTGWFPADCVEEVQMRQYDTR----------------------------------------------------------------------HETRE-----DRTKRLFRHYTVGSYDSLTS--HSDYVIDDKVAILQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWKAGLRTGDFLIEVNGVNVVKVGHKQVVGLIRQGGNRLVMKVVSVTRKPE-EDSARRRAPPPPKRAPSTTLTLRSKSMTAELEELASIRRRKGEKLDEILAVA--AEPTLRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGP-------EKLPGSLRKGIPRTKSVGEDEK---LASLLEGRFPRSTSMQDTVREGRGIPPPPQTAPPPPPAPYYFDSGPPPTFSPPPPPPGRAYDTVRSSFKPGLEARLGAG----AAGLYDSGTPLGPLPYPERQKRARSMIILQDS---APEVGDVPRPAPAATPPERPKR-RPRPSGPDSPYANLGAFSASLFAP--SKPQRRKSPLVKQLQVEDAQERAALA--VGSPGPVGGSFAREPSPTHRG-------PRPGGLDYSSGEGLGLT-----FGGPSPGPVKER--RLEERRRSTVFLSVGAIEGS-PPSADLPSLQPSRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQ-TPSRSPTPVHSPDADRPG-PLFVDVQTRDSER----GPLASPAFSPRSP------------AW-IPVPARREAEKPT-REERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPNRLG-----------AEEERPGTPELAPTP-----MQAAAVAEPMPSPRAQPPGSIPADPGPGQGSSEEEPELVFAVNLPPAQLSSS--DEETREELARIGLVPPPEEFANGILLATPPPGPGPLP---TTVPSPASGKPSSELPPAP------------------------------ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHATSTGLTSAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSPIAAARCAVVPSAG-WLFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPSPGSGP------SAGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKEDFVELGVTRVG--HRMNIERALRQLDGS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4ACU6-1", "uniprot_id": "SHAN3_MOUSE", "id": "Q4ACU6-1", "name": "SH3 and multiple ankyrin repeat domains protein 3", "aln": "--------------------------------------------------------------------------------------MDGPGASAVVVRVGIPDLQQTKCLRLDPTAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQDYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLRNGGAHLDFRTRDGLTAVHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRR-----------------LAGPSGLASPRPLQRSASDINL----------KGD-QPAASPGPTLRSLP-------HQLLLQRLQEE------KDRDRDGELENDISGPSAGRGGHNKISPSGPGGSGP-----APGPGPASPAPPAPPPRGPKRK---LYSAVPGRKFIAVKAHSPQGEGEIPLHRGEAVK------------------------------------------------VLSIGEGGFWEGTVKG--RTGWFPADCVEEVQMRQYDTR----------------------------------------------------------------------HETRE-----DRTKRLFRHYTVGSYDSLTS--HSDYVIDDKVAILQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVGLIRQGGNRLVMKVVSVTRKPE-EDGARRRAPPPPKRAPSTTLTLRSKSMTAELEELASIRRRKGEKLDEILAVA--AEPTLRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGP-------EKLPGSLRKGIPRTKSVGEDEK---LASLLEGRFPRSTSMQDTVREGRGIPPPPQTAPPPPPAPYYFDSGPPPTFSPPPPP-GRAYDTVRSSFKPGLEARLGAG----AAGLYDPSTPLGPLPYPERQKRARSMIILQDS---APEVGDVPRPAPAATPPERPKR-RPRPSGPDSPYANLGAFSASLFAP--SKPQRRKSPLVKQLQVEDAQERAALA--VGSPGPVGGSFAREPSPTHRG-------PRPGSLDYSSGEGLGLT-----FGGPSPGPVKER--RLEERRRSTVFLSVGAIEGS-PPSADLPSLQPSRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQ-TPSRSPTPVHSPDADRPG-PLFVDVQTRDSER----GPLASPAFSPRSP------------AW-IPVPARREAEKPP-REERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLG-----------AEEERPGTPELAPAP-----MQAAAVAEPMPSPRAQPPGSIPADPGPGQGSSEEEPELVFAVNLPPAQLSSS--DEETREELARIGLVPPPEEFANGILLTTPPPGPGPLP---TTVPSPASGKPSSELPPAP------------------------------ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASTGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSPIAAAR----------LFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPSPGSGP------SAGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKEDFVELGVTRVG--HRMNIERALRQLDGS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYB0-1", "uniprot_id": "SHAN3_HUMAN", "id": "Q9BYB0-1", "name": "SH3 and multiple ankyrin repeat domains protein 3", "aln": "---------MQLSRAAAAAAAAPAEPPEPLSPAPAPAP--APPGPLPRSAADGAPAGGKGGPGRRAESPGAPFPGASGPGPGPGAGMDGPGASAVVVRVGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQEYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLKNGGAHLDFRTRDGLTAVHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGITDENGWQEIHQACRFGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQESCARVLLFRGANRDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRR-----------------LAGPSGLASPRPLQRSASDINL----------KGEAQPAASPGPSLRSLP-------HQLLLQRLQEE------KDRDRDADQESNISGPLAGRAGQSKISPSGPGGPGP-----APGPGPAPPAPPAPPPRGPKRK---LYSAVPGRKFIAVKAHSPQGEGEIPLHRGEAVK------------------------------------------------VLSIGEGGFWEGTVKG--RTGWFPADCVEEVQMRQHDTR----------------------------------------------------------------------PETRE-----DRTKRLFRHYTVGSYDSLTS--HSDYVIDDKVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTRKPE-EDGARRRAPPPPKRAPSTTLTLRSKSMTAELEELASIRRRKGEKLDEMLAAA--AEPTLRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGP-------EKLPGSLRKGIPRTKSVGEDEK---LASLLEGRFPRSTSMQDPVREGRGIPPPPQTAPPPPPAPYYFDSGPPPAFSPPPPP-GRAYDTVRSSFKPGLEARLGAG----AAGLYEPGAALGPLPYPERQKRARSMIILQDS---APESGDAPRPPPAATPPERPKR-RPRPPGPDSPYANLGAFSASLFAP--SKPQRRKSPLVKQLQVEDAQERAALA--VGSPGPGGGSFAREPSPTHRG-------PRPGGLDYGAGDGPGLA-----FGGP--GPAKDR--RLEERRRSTVFLSVGAIEGS-APGADLPSLQPSRSIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQ-APSRSPTPVHSPDADRPG-PLFVDVQARDPER----GSLASPAFSPRSP------------AW-IPVPARREAEKVP-REERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGG----------AEEERPGTPELAPAP-----MQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQLSSS--DEETREELARIGLVPPPEEFANGVLLATPLAGPGPSP---TTVPSPASGKPSSEPPPAP------------------------------ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSPIAAAR----------LFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGPGPG-----APGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELGVTRVG--HRMNIERALRQLDGS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HWG2-1", "uniprot_id": "A0AC58HWG2_DANRE", "id": "A0AC58HWG2-1", "name": "SH3 and multiple ankyrin repeat domains protein 3", "aln": "MPVSAGSGKHEPSQPRDRPQQQPEVPSEPPSALPSVSPSLSLPLSLPLLIYSRPAQPLPRHLSSSTSRGESARSPHADVCRAPAGPMEEPQGNTLVVRIGIPDLQQTKCMKFNVESPIWLSKQRILCTLNQSLKDVLNYGLFLPAYNGKAGKFLDEQRTLKEYPLPAVSPVPYLEFRYKRRVYTQAHLDEKQLSKLHTKANLKKFMEYVQQRNVEKVSKFLEKGLDPNYHDPDTGECPLTMASQLEGCAELIKVLKNGGAHLDFRTRDGITALHKAVRTKNHTALITLLDLGASPDYKDSRGLTPLYHSSMVGGDPYCCELLLHDHAQVGCMDENGWQEIHQACRHGHVQHLEHLLFYGADMSAQNASGNTALHVCALYNQDSCARVLLFRGANKEIKNYNSQTAFQVAIIAGNFDLAEIIKTHKASDVVPFRETPSYTNRRR-----------------VTGGDTLTSSRSLPRSASDNNLNN--------VADASHAHSPVPSLRSLPPLAHSGIDPAADGSLQSTGSSLSSHSRSPSLQRVTEEASVLAGRRHMPLMHSHSRGRLSPGTVQRDPSPPPVGPSHTLSGARGPKRK---LYSAVPGRTFIVVKPYSPQGEGEIQLNRGERVKDYHSNAVEEENVYEEIKLESIKESEEEESPYVEHEIKEEDAHACVDDKVLSIGEGGFWEGTVKG--RTGWFPADCVEEVQMRQYDPR----------------------------------------------------------------------LETRE-----DRNKRLFRHYTVGSYDNFTS--YSDYIIEEKNAMLQKKENEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVSLIRQGGNSLLMKVASVTRKPESEETVRKKAPPPPKRAPSTTLTLRSKSMTAELEELASARRRRGERLDEILAS---QETVLRP-KVEADYRAATVKQRPTSRRITPAEISSLFERQGLALHGALHPALEKAHMQLPKSMARTKSFGATEEDRLSALAAEHRFPRSSSMTDSLRDSHSIPPPPQMAPPPPPSLYYLDTGPPPSFCPPPPP-GRLHDPSRSSFKPGSEPRLHALPQTMSAELYEP---PRHASHMERQKKARSMIILQDSSHLPVEPTDIPRPGPVSTPPERIKR-KGR--IIDNPYANVGQFSVGMFTPTPSKPQRRKSPLVKQLQVEDAQERASLA--LASIHAREHSPSGRLAAQHTSRSDFFHQQQQLLHERSQAHAEGLLQGKGPFAAAIADAVKDRERRLEERRKSTVFLSVGTMEGSSAPPPEAPSLTPSRSVDERMLTR--ELG---QLPPPALALRP-------SPGGTTFIHPLTGKPLDPNSPLALALAARERALTSQ-SQSPSSSPEPRTKHETAGGVLYMETQTKEAERSEGEGGFASPPFSPATKRIYETSVPTSKIQWGSPISTRKELETRTERKEERKIEDKKSMIISIMDTSQQKTAGLIMVHATSNGQAVGPSPERSVPSPKGILSESPKPMLAEIKRAKSPGPEAPSISTPPPTAAPTSQPPPSPSSDKTLAQGSSEEDAEP-YTVTLPPAMLSSS--DEETREELRKIGVVPPPDEFSNGLLAKTPETAVPPAPTLTQTTPSTLPSAPPAPPPPAPSAAVAAAAQVPASSGLQAASGKPSESHLGPESAADSGVEEVDTRSSSDHHLETTSTISTVSSMSTLSSESGEPTDTYTTHADGQTFILDKPPVPPKPKLKSQLSKGPVTFRDPLLKQSSDSELLSQQHAAALAAAAGASGPARPRYLFQRRSKLWGDTVEPRPLSGAEEGKPTVISELSSRLQQLNKDTRSLGEEPLG---ASLDPGRKSPVVGPR----------LFSSLGELHTISQR------GYGTTYTIRPGSRYPVTRRTPS---PGSPDRSDPLGPIRGFGLATSPITPPTILKSSSLSLPHEPKEVRFVMRSSSARSRSPSPAPSPGMTS----------PLLTLRPFHQKPLHLWNKYDVGDWLASINLAEHRDRFQEHEIEGSHLPALTKEDYAELGVTRVG--HRMNIERALKQLLES---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ARK3-1", "uniprot_id": "A0A8M3ARK3_DANRE", "id": "A0A8M3ARK3-1", "name": "SH3 and multiple ankyrin repeat domains protein 3", "aln": "---------MPISPPADGKHEALDRPWQQHAPTN----------------------GNHGDDSIRTSPGSKCGS----------EPMEDLHGNAVVIRIGIPDLQQTKCLRLDLEAPVWVCKQRVLVTLTQSLTDVLNYGLYLPAFNGRAGKFLDEERLLREYPLPTVTPVPYLEFRYKRRVYTQSHVDDKQLAKLHTKANLKKFMEYVQQRCVDKVCRFLEKGLDPNFHDSDSGESPLTLVAQLDTCADLIKVLRSGGAHLDFRTRDGLTALHKAAQTHNHVALTTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLYDHAQLGYSDENGWQEIHQACRHGNVQHLEHLLFYGAEMSAQNASGNTALHLCALYNQEGCARVLLFRGANKEIKNYNNQTAFQVAIIAGNFDLAEIIKIHKTSDVVPFRETPSYSSRRR-----------------AVCVS---PRRSLMRSASDNAL-----------DETLTAPSPAPSLRSLP-------------PLEPD-------------DTVPSQRSPQAAHTHTRSLRRHTRSGGHL-----SPGSPVQREPSPPAVPRGPKRR---LYSAVPGRTFIAINSHTPQGEGEITLNRGERVK------------------------------------------------VLSIGEGGFWEGSVKG--RTGWFPAHCVEEVQMRQYDPR----------------------------------------------------------------------LETRE-----DRTKRLFRHYTVGSYDNYTS--YSDYVIEEKSATLQKRDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGVSVVKVGHRQVVSLIRQGGSRLVMKVVSVTRKPDTGDVVRKKAPPPPKRDPSTSLTLRSKSMTAELEELASRRRR-GEKLDEMLSSPKEQVVVMRQRPVDSDSRAATVKQRPTSRRITQAEISSLLERQGLPIS-ELSLAVDKSHMQLPRGMSRTKSFGAPEDDRISALIGEHRFPRSSSMTDSFRQD-SIPPPPQTAPPPPPTPYFLDSGPPPSFLPPPPP-SRAANQSRSSFRPGAEPKIHGP------------------VTTDRQRKTRSMIILQDTSHLPVEPTPITRPQTPTSGPVPPERGRRRGPPVENPYANVGRLSA-VYTP--TKPQRRKSPLVKQGPVEEG--AAAHS--SRDPSPLGGSRIPHSSRAEQF-------QQQVLSERARITPPGAR------------------------RRPSVFLSV---EGGATEPQTTPLLSQSHSVDE-----------LAELPPPAPMLSP-----GPPPGGTTFIHPLTGRPLDPSSPLALALAARERALSGRNTPTPTPSPTPSP------------TQGRAVER-----------------------------------PETEGGATPPAPLEAPPSNSWRDEPVSITETASQVTSGSPGS-GRSLEEALAPPG-----------VQNIQPALMDTEHTP--------PAVPPTLPSP---APTLSNLTARSMTMSSEEEAEP-YTVTLPPALLSSS--DEETREELRKIGLVPPPQPFANGLLIKETSKATLSIS-----PSGSRPSIAKTSSGKAS------------------------------DSTADSGVEDP--------HMETTSTVSTVSSMSTLSSES-----TDSAHAS-------------KPRCGVGRGR-PAHLRDPLLKQSSDSELLPHP---------PSTGPSRPRYLFQRRSKLWGE--EPRAQMGSSDES----RPAAMGAELLSKDTHSLGEEPPMG--APLDPGRRSPVGGARCEENGGESKSLFSSLGELHTISQR------SYGTTFTIRPGSRYPVTRRTPSP--GATPERSEPLGPVRTFG---PHHHHHTILKSSSLSLPQEPKEVRFVMRSASARARSRSPSPSPCASPCPSPVLG--APLLALRPFRQRPLALWSKYDVGEWLESVGLGEHRARFLEHEIEGAHLPALTKDDLAELGVTRVG--HRMNIERALKQLLES---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9K8-1", "uniprot_id": "A1Z9K8_DROME", "id": "A1Z9K8-1", "name": "", "aln": "---------------------------------------------------------MSGSGAFDD------------------EPPPEPRDGWLLVRIHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYPFN--GPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACRHGLVQHLEHLLFYGADMDGRNASGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAVIAGNLELAEIIENYKSEDIVPFRGPPRYNPKRRSGIGWLSANGAAGAALLAAAGGGFGGAMVGSNGAANGNNGAGGVGLMLSHQNHQQHHAGHHQQQHMHHQHHQNHHQQLQQQQLPHLHTLQLHGPPSPCPSEHMLGAYSSASSSLSEGSSGHRSHEDDISIVTDKSLGDTSDIISDSSGVGTNSDSAACSIGHPSTTVVCMEPYAGNTVGHIRLQPGDVIE------------------------------------------------VVGSTDCGLLEGYVRGTNQSGFFPADCVQEVSLRQKHITNVMTASTGMAPQQQQQQHLQQAPAGSSAASYQGSPQLSLGGHSGSSSTLLQQPHQSPSLSVASNGSCQQPLESNEGGASGNGINNRNNNHSVGQYSSATAPRIKKSAYNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAG--ALVNLTVVSPQFPHQMQASAQYLPSGARAGSHHLNSGPSTPQSSHRQCATLPRKMTGPGGSGPGSSSGGSVRMAPMPPRRDPKTTLSVGRARAKSMVAGLENGGEKEDDLPHT------KSNSVESIATPTPTGIQTGPGTP---VQLRTASIKARPTSSRITAAELEELFQRQQGEGSAANASRYATMMTSSRFQSGTDS-GAATPPASNGSPMRSGPLVYGS---------------------VAEMKRKTARSKHGSGTLRGKPVATPTVGPGGAGGGRDLKRFHSTPDLHGPQLHGSASSIWQASGKGHHSQDDVATLHASLQRLNSNQGELKLGGLGAGSATGAGGAVLPPPNHPP-------PPPPVGQVVKVETRSSVS------EYESTISLQQKLKKRTENDAVTSAAIDGVQSSFNPSANAKIYASPQELRNVMAWKLRQAQEKPSQETSAGSQQP-----VSQYAAPTQMRPAQQQQQAQQPPTALASHYAAPQVQVQQVQQVQQSPQQSAPQSPPAPPLPQAAPVPAQNG----NGNGSTSGAGSAP----------------PIPEPDYSCSESDGEDENSILVARNTKLNEKIALFDVPETSGNSQASGSSSNSGSAS------------ISHSLSVEEIQRIR--------SNLKTSKSSPNGFAKKPEEEKPQQEQQQSHQQPQQLLQPGEDECDNSSSGVSSEQEQLALAAGVTLPGGGKPTDTIKKKPSVTIVEEP-------KTIPDQPSSNTSHTT------------------------------KPMAKTTISIGGGGSAVPTATLTVKQLVQQQHAPVIQQQQQQLGSKQPVTAASTNKFTQQSNINSNVMSPQVLGRIPSHHHQ-QQSSNPNQKLIATQQQILQQQQQQLAHQQHLQQILKAKAAAAGGASNTAVLVAKHQQKLHKGTSSGHESEMETRSDLEDDDGDLSPSPPAKAFQRHNSLTRKQAAAIAMQRGATRTTAVSLMQLPPPLEADSDGEPSQLTLQRQQSHHPSQTHPHPHQLQQQLQLQQQQQQQQQQQQPMAAHIVGMLPSGQLVAVASGAVAGVPGVGATAVQQGNNNLQQLCTDNLVLAPPPQFCDCNDAKHAPQPHLPTSQYHPQQQQQQQHQQQQQQQQQLQQQLQQQQMLQMHQRLSGGAGAGAVGTLGRVRIVGAMPKANHHRLH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::*: :*:*: **::: :* **::* :* :.* : :****: *. .*:*******:* * :** *: ***::****** :*::*: ***:***::*:: :: .:*:.:: ******:* .::*: **::.: . .*: .* .*** **:**:** **:* *.. . *: ***:*****:*:*.**:**** * :. * **:*** :* *.:**:*:*****.* ************:*..:*****:.**:**: **:.***:******:: :*: .**.:***:****::***:*: :* .*:**** .* * :** . . ..*:: : : : : . :. . . . . *.: . *. ..: ::.:: : *.* *: *: :: *:. : *: ** *:* ::*:***.**:**.:** . *:.* : :. .:::**.*.. *: .. : : : :: .****:******.: : :: *: *******:.** *** ****.****: :** .*....*.*** :**..* ::::. *: : . : *. * * *. ..: :. .: *: *: .. . : * ::: *. :: :. . .. :.:.*. .: .: . . * .*.:* . : : * ... : : ... * . . . . .. . : . : : :: :.: : . . : : ..* : . * : :.* :.* . :. . . . . : . . . . :: :.. .:.: : ... * ...* ::* : ..* *** : : :* . . : . . . : :. :. : : . . . . . : . .:* . .*.::.: . *** ..* .: *:. * ... : . . . .. . : :. .. *.: :. *.. : . ..:..:. . . * : .: * :: ....:.:*:. : : : ::: :: * :. . : . . : .:. . .: . ::..: : :: .* :. . : ::: : :: * : : :* *..* . . . . :* :. . : * * . . : . ::: : ::::: :: : : *. ** *:.* *: : ", "identical_positions": 290, "similar_positions": 483, "identity": "13.65%" }, { "cls_id": "homologset.agr.MGI:1930018", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9H9-1", "uniprot_id": "A0A0G2K9H9_RAT", "id": "A0A0G2K9H9-1", "name": "", "aln": "MFKRTVLSCPPPAAPPLQARGAFRSFPHFWGEDFLASLMFKIQLEPLKLRAWTLNGFVKFRNKEPSTGPVAVMGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRSLYDQYGEEGLKTGG---GTSGGSG-GSFHYTFHGDPHATFASFFGG---SNP---FDIFFASSR---STRPFSGFDPDDMDVDED--EDPFGAFGRFGFNGLS-----RGPRRAPEPLYP-RRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDN-IPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDG-RVIPLP-CNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89114-1", "uniprot_id": "DNJB5_MOUSE", "id": "O89114-1", "name": "DnaJ homolog subfamily B member 5", "aln": "------------------------------------------------------------------------MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRSLYDQYGEEGLKTGG---GSSGGSG-GSFHYTFHGDPHATFASFFGG---SNP---FDIFFASSR---STRPFSGFDPDDMDVDED--EDPFGAFGRFGFNGLS-----RGPRRAPEPLYP-RRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDN-IPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDG-RVIPLP-CNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75953-3", "uniprot_id": "DNJB5_HUMAN", "id": "O75953-3", "name": "DnaJ homolog subfamily B member 5", "aln": "------------------------------------------------------------------------MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRGLYDQYGEEGLKTGG---GTSGGSS-GSFHYTFHGDPHATFASFFGG---SNP---FDIFFASSR---STRPFSGFDPDDMDVDED--EDPFGAFGRFGFNGLS-----RGPRRAPEPLYP-RRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDN-IPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDG-RVIPLP-CNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WUU0-1", "uniprot_id": "A5WUU0_DANRE", "id": "A5WUU0-1", "name": "", "aln": "------------------------------------------------------------------------MGKDYYKILGIPSGSNEDEIKKAYRKMALKFHPDKNKDPNAEEKFKEIAEAYEVLSDPKKRVIYDQYGEDGLKTGGT--GSSSGQG-TTYHYTFHGDPHATFASFFGG---SNP---FDIFFGSSRQRGNTNGFPDHGDHDMDIDMDGEDDPFSSFSHFGFNGVNGFHHGGGRRHRNEPLHGGRKKLQDPPVVHELKVSLEEIFHGCTKRMRITRRRLNPDRKTMRTEDKILNIVIKRGWKEGTKITFPKEGDETPEN-IPADIAFVLKDKGHPLFRRDGSNIIYTTKIGLKEALCGCTVNIPTIDN-RAITLP-CNDIIKPGTIKRLRGEGLPFPKNPSQRGDLIVEFQVRFPDRIPPQSREIIKQHLPQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPY9-1", "uniprot_id": "Q9VPY9_DROME", "id": "Q9VPY9-1", "name": "J domain-containing protein", "aln": "------------------------------------------------------------------------MGKDYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYDKYGEDGLKSGGT--R-NGGPSSNSFTYQFHGDPRATFAQFFGN---SNP---FASFFDMGD-----NLFDKK-VFDLDTEPDFFSSPFGGIGSRHGLGSGFRPSFRSHSFNVHTPFK-KEQKQDPPVEHDLYVTLEEIYHGCVKKMKISRRIVQADGSS-RKEEKFLAISIKPGWKSGTKVTFQKEGDQAPGK-IPADIVFIIRDKPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRIST-MQEIIKPNTVKRIQGYGLPFPKDTTRKGDLLVAFDIQFPEKLTAAQKEVLKDML---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24133-1", "uniprot_id": "DNAJ1_DROME", "id": "Q24133-1", "name": "DnaJ protein homolog 1", "aln": "------------------------------------------------------------------------MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFDNYGEDGLKGGQP--GPDGGGQPGAYTYQFHGDPRATFAQFFGS---SDP---FGAFFTGGD-----NMFS-------GGQGGNTNEIFWNIGGDD-----------MFAFNAQAPSR-KRQ-QDPPIEHDLFVSLEEVDKGCIKKMKISRMATGSNGP--YKEEKVLRITVKPGWKAGTKITFPQEGDSAPNK-TPADIVFIIRDKPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNP-NHEIIKPTTTRRINGLGLPVPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSELLPN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2U5-1", "uniprot_id": "Q9W2U5_DROME", "id": "Q9W2U5-1", "name": "J domain-containing protein", "aln": "------------------------------------------------------------------------MPKDYYKILGIQRTANDGEIRKAYHKQALRYHPDKNKSPQAEEIFKQVAKAYEVLSDKKKRGSYDSRNDKGTRRNTA--NQGSGFGDGTAFGSCGGGSGSGSGGGSGGGRQNNPRANFGRFFDNSE---SYSTFFEDIENDFDSDDD---VLLGGG-------------------AGAPKRRCEQQSPQSSIEHVIYVALEDIANGCNRRMKISR-ASGRNGVDGVQYDRILTVKIPPGCKAGTKICFPNEGIQLPNL-EPANVVFIIRDKPHPIFRRDGNNLLYTAEISLKDALCGLHVMVPTLLGRPMELKTDVGEVISPKSVRRILGYGLPDSINNSRRGSIVVRFSIQFPDAISKELASSLDRLLQN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25294-1", "uniprot_id": "SIS1_YEAST", "id": "P25294-1", "name": "Protein SIS1", "aln": "----------------------------------------------------------------------MVKETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTG--DTEKFKEISEAFEILNDPQKREIYDQYGLEAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSN---EDAFNIFSQFFGGSSPFGGADDSGFSFSSYPSGGGAGMGGMPGGMGGMHGGMGG-------MPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGR-----KGPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSR--VQPVQPSQTSTYPGQGMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDENF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *.:**: :.: *::*.*:* **::**** . : **::::*:::*.* .** :*. . .. : . .. * . .. .:. * ** . . . : .: : *:**:: * : ::* * . . : : : * * ***: : ::* * : *::::* *. *:*:* :: *: : :*::* * : *: . : :.* * *:* . :::*.::* :.: :* : :. : ", "identical_positions": 56, "similar_positions": 99, "identity": "12.61%" }, { "cls_id": "homologset.agr.MGI:1930020", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVB7-1", "uniprot_id": "LENEP_RAT", "id": "Q9WVB7-1", "name": "Lens epithelial cell protein LEP503", "aln": "MKPPMQPLTQALPFS----LRDALQGTGLRVPVIKMGTGWEGMYRTLKEVAYILLCCWCIKELLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVB6-1", "uniprot_id": "LENEP_MOUSE", "id": "Q9WVB6-1", "name": "Lens epithelial cell protein LEP503", "aln": "MRPPTQPLTQALPFS----LRDALRGTGLQVPVIKMGTGWEGMYRTLKEVAYILLCCWCIKELLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5L5-1", "uniprot_id": "LENEP_HUMAN", "id": "Q9Y5L5-1", "name": "Lens epithelial cell protein LEP503", "aln": "MQPRTQPLAQTLPFF----LGGAPRDTGLRVPVIKMGTGWEGFQRTLKEVAYILLCCWCIKELLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P644-1", "uniprot_id": "A0A8M1P644_DANRE", "id": "A0A8M1P644-1", "name": "", "aln": "MQP-QRPLPQAMPSSPGRNLGDAALGTGTGKRLLG-GNMAYGVIQSLKECLYFLLCCWCIKEILD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* :**.*::* * .* .** :: *. *. ::*** *:*********:**", "identical_positions": 27, "similar_positions": 15, "identity": "41.54%" }, { "cls_id": "homologset.agr.MGI:1930025", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R5D7-1", "uniprot_id": "M0R5D7_RAT", "id": "M0R5D7-1", "name": "", "aln": "MMLNWKLLGLLVLCLFAGGISGS-DDPSPKSTDTQEE-NSPPLPLGPPIPGDPWPGAPPLFDEPPPPGSNRPWRDLPDSGAWPPKPPSTDPPKPPLPDDPWPAGTQPPENPWPPAPEMDSESQEEPDLDPPREEYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZC9-1", "uniprot_id": "PS1C2_MOUSE", "id": "Q80ZC9-1", "name": "Psoriasis susceptibility 1 candidate gene 2 protein homolog", "aln": "-MLTWKLLGLLVLCLCAGGISGN-GDPSPGSTDTHEEEDSPPLPLGPPIPGDPWPGAPPLFDEPPPPGSNRPWRDLPDSGAWPPKPPSTDPPKPPLPDDPWPAGTQPPENPWPPAPEMDHESQEEPDLDPPQEEYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIG4-1", "uniprot_id": "PS1C2_HUMAN", "id": "Q9UIG4-1", "name": "Psoriasis susceptibility 1 candidate gene 2 protein", "aln": "MILNWKLLGILVLCLHTRGISGSEGHPSHPPAEDREEAGSPTLPQGPPVPGDPWPGAPPLFEDPPPTRPSRPWRDLPETGVWLPEPPRTDPPQPPRPDDPWPAGPQPPENPWPPAPEVDNRPQEEPDLDPPREEYR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.*****:***** : ****. ..** .:: :** .**.** ***:************::***. ..*******::*.* *:** ****:** ********.************:* ..*********:****", "identical_positions": 93, "similar_positions": 29, "identity": "68.38%" }, { "cls_id": "homologset.agr.MGI:1930036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRE1-1", "uniprot_id": "D3ZRE1_RAT", "id": "D3ZRE1-1", "name": "Piwi-like protein 2", "aln": "MDPVRPLFRGPTPVHPSQC--VRMPGCWPQAPRPLEPAWGRAGP-----AGRGLVFRKPEESSPPLQPVQKESVG---LVSMFR---------GMGLDTALRAPSKREVPPLGRG-VLGRGLSANVVRKDREESRS---SLP---DPSVLAAGDSKLAEASVGWSRMLGRGSSDVS---LLPLGR-AAGSIGRGVDKPPSAFGLTARDP------------------------------------PRLPQPPTLSPTSLHSSD------------PPPVLTIERKEKELLVKQGSKGTPQSLGLNLIKIQCHN-EAVYQYHVTFSPNVECKSMRFGMLKDHQSVTGNVTAFDGSILYLPVKLQQLVELKSQRKTDDAEISIKIQLTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDSVLDVMHAIYQQNKEHFQDECSKLLVGSIVITRYNNRTYRIDDVDWNKTPKDSFVMSDGKEITFLEYYSKNYGITVKEDDQPLLIHRPSERQNNHGTLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLTQQINLSPKQHHSALECLLQRISQNETANNELTRWGLSLQKDVHKIEGRLLPMERINLRNTSFVTSEDLNWVKEVTRDASILTIPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRISPPAWVELKDDRIETYIRTIQSLLGVEGKIQMVVCIIMGTRDDLYGAIKKLCCVQSPVPSQVINVRTIGQPTRLRSVAQKILLQMNCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKYYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFDNYHPKMVVFVVQKKISTNLYLAAPDHFVTPSPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYICVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGQILHHEPAIQLCENLFFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDG1-1", "uniprot_id": "PIWL2_MOUSE", "id": "Q8CDG1-1", "name": "Piwi-like protein 2", "aln": "MDPVRPLFRGPTPVHPSQC--VRMPGCWPQAPRPLEPAWGRAGP-----AGRGLVFRKPEDSSPPLQPVQKDSVG---LVSMFR---------GMGLDTAFRPPSKREVPPLGRG-VLGRGLSANMVRKDREEPRS---SLP---DPSVLAAGDSKLAEASVGWSRMLGRGSSEVS---LLPLGR-AASSIGRGMDKPPSAFGLTARDP------------------------------------PRLPQPPALSPTSLHSAD------------PPPVLTMERKEKELLVKQGSKGTPQSLGLNLIKIQCHN-EAVYQYHVTFSPSVECKSMRFGMLKDHQSVTGNVTAFDGSILYLPVKLQQVVELKSQRKTDDAEISIKIQLTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDSVLDVMHAIYQQNKEHFQDECSKLLVGSIVITRYNNRTYRIDDVDWNKTPKDSFVMSDGKEITFLEYYSKNYGITVKEDDQPLLIHRPSERQNNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLTQQINLSPKQHHGALECLLQRISQNETASNELTRWGLSLHKDVHKIEGRLLPMERINLRNTSFVTSEDLNWVKEVTRDASILTIPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRISPPAWVELKDDRIETYIRTIQSLLGVEGKIQMVVCIIMGTRDDLYGAIKKLCCVQSPVPSQVINVRTIGQPTRLRSVAQKILLQMNCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKYYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFDNYHPKMVVFVVQKKISTNLYLAAPDHFVTPSPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYICVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGQILHHEPAIQLCGNLFFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TC59-1", "uniprot_id": "PIWL2_HUMAN", "id": "Q8TC59-1", "name": "Piwi-like protein 2", "aln": "MDPFRPSFRGQSPIHPSQCQAVRMPGCWPQASKPLDPALGRGAP-----AGRGHVFGKPEEPSTQRGPAQRESVG---LVSMFR---------GLGIETVSKTPLKREMLPSGRG-ILGRGLSANLVRKDREELSP---TFW---DPKVLAAGDSKMAETSVGWSRTLGRGSSDAS---LLPLGR-AAGGISREVDKPPCTFSTPSRGP------------------------------------PQLSSPPALPQSPLHSPD------------RPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCHN-EAVYQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVMHAIYQQNKEHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CEI6-1", "uniprot_id": "PIWL2_DANRE", "id": "A2CEI6-1", "name": "Piwi-like protein 2", "aln": "MDPKRPTFPSPPGVIRAPWQQSTEDQSQLLDQPSLGRARGLIMPIDEPLPGRGRAFSVPGEMPVRFGRGITQSIAAEPLVGMARGVRLPMEEGGFGRGRGFLLPTPEPTVGIGRGAAIGPVPTLDIQKAEVEEKMP---ELQAEVAPTVAKVGSPGTGSSLVSMFRGLGIEPGKTWGRGAAPVGRGAAGDMGADLQPKPTIIGASLTPEREEVRSEESISFLGRGFTGFGRAAMPHMTVGRGPIGPLSPSPSVAAPFSLISASSASEDAPVAPGTPPKVEVKIETVKEPLQKIGTKGSPIPIGSNYIPICCKN-DAVFQYHVTFTPNVESLSMRFGMMKEHRPTTGEVVAFDGSILYLPKRLEEVVHLKAERKTDNQEIDIKIQLTKILPPSSDLCIPFYNVVLRRVMKILGLKLVGRNHYDPNAVVILGKHRLQVWPGYSTSIKHTDGGLYLVVDVSHKVLRNDSVLDVMNLIYQGSRESFQDECTKEFVGSIVITRYNNRTYRIDDIEWSKSPKDTFTLADGSVTTFVDYYRKNYGITIKELDQPLLIHRPKERSRPGGKVITGEILLLPELSFMTGIPEKMRKDFRAMKDLTMHINVGAQQHTQSLKQLLHNINSNNEALSELGRWGLSISQEILVTQGRTLPSETICLHSASFVTSPAVDWSRELVRDPSISTVPLNCWAVFYPRRATDQAEELVTTFSRVAGPMGMRVERPIRVELRDDRTETFVKSIHSQLTSEPRVQLVVCIMTGNRDDLYSAIKKLCCIQSPVPSQAINVRTISQPQKLRSVAQKILLQINCKLGGELWTVNVPLKYLMVIGVDVHHDTSKKSRSVMGFVASLNSMLTKWYSRVTFQMPNEEIINGFRVCLLAALQKYYEVNHAFPEKIVIYRDGVSDGQLKTVEHYEIPQILKCFETIPNYEPKLAFIVVQKRISTTLYSYGSDHFGTPSPGTVLDHTVTNRDWVDFYLMAHSIRQGCGLPTHYITVYNTANLTPDHLQRLTFKMCHLYWNWPGTIRVPAPCKYAHKLAFLSGQYLHSEPAIQLSEKLFFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLK0-1", "uniprot_id": "AGO3_DROME", "id": "Q7PLK0-1", "name": "Protein argonaute-3", "aln": "------------------------------------------------MSGRGNLLSLFNKNAGNMGKSIS-----------------------------------------SKDHEIDSGLDFNNSESSGERLLSSHN-----------------IETDLITTLQHVNISVGRGRARLIDTLKTDDHTSNQFITSESKENITKKTKGP---------------------------------------ESEAIASENGLFFPD---------------------------LIYGSKGSSVNIYCNYLKLTTDESKGVFNYEVRFFPPIDSVHLRIKYLNDHKDKLGGTKTFDGNTLYLPILLPNKMTVFIS-KAEDVELQIRILYKKKEEMRN--CTQLYNILFDRVMKVLNYVKFDRKQFDPSRPKIIPLAKLEVWPGYVTAVDEYKGGLMLCCDVSHRILCQKTVLEMLVDLYQQNVEHYQESARKMLVGNIVLTRYNNRTYKINDICFDQNPTCQFEIKTG-CTSYVEYYKQYHNINIKDVNQPLIYSIKKSRGIP-AERENLQFCLIPELCYLTGLRDEVRSDNKLMREIATFTRVSPNQRQMALNKFYENVSNTPAAQEILNSWGLSLTNNSNKISGRQMDIEQIYFSKISVSAGRSAEFSKHAVTNEMLKVVHLSKWIIIHLRNYRQAATSLLDNMKQACESLGMNISNPTMISLDHDRIDAYIQALRRNITMN--TQMVVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTLQNDLKIRSVVQKIVLQMNCKLGGSLWTVKIPFKNVMICGIDSYHDPSNRGNSVAAFVASINSSYSQWYSKAVVQTKREEIVNGLSASFEIALKMYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYEIPQ----FEMVCGNRIKISYIVVQKRINTRIFSGSGIHLENPLPGTVVDQHITKSNMYDFFLVSQLVRQGTVTPTHYVVLRDDCNYGPDIIQKLSYKLCFLYYNWAGTVRIPACCMYAHKLAYLIGQSIQRDVAEALSEKLFYL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*** : . . .:. :. : . . *. . : : :. . .: . . : . . . * .. *:**:. : * : : .: ..*::*.* * * ::. :*: :::*: * . :***. **** * : : : . *::. *:.*:* .* . * :**::: ****:*. ..*: :**. :: :*::**** ::: . .*** * ****::: :. **::: :** . * :*:.. * :**.**:********:*:*: :.:.*. * : * ::::** : :.*.:*: :***: ..* . . :: *:***.::**: ::::.* : *:::: .:..:*: :*: : ..: .. * . * *** : :: .** : * * : . *. :. :: :. . : : .: : * ::: :. : * .*: :.: . .:**.:. * :.* .** :::::::: : : *:**** . *** *.****:** : *:***.:*.:*: : ::***.***:**:******.** *.:*:* :*: *:* :**.*. .** .****:* ::***:...* .:**::.: .: :*: : : * :* :*::****:.**** * :***** ** . . . *: :****:*.* :: . :: .* ****:*: :*. : **:*::: :*** ****: : : .* ** :*:*::*:*.:*:**.**:*:** * ******:* *: :: : * *. :**:*", "identical_positions": 247, "similar_positions": 312, "identity": "23.52%" }, { "cls_id": "homologset.agr.MGI:1930042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z924-1", "uniprot_id": "D3Z924_RAT", "id": "D3Z924-1", "name": "DNA cross-link repair 1A protein", "aln": "MLEDAFWEEDIWEYKSKRKPKPVHPNSCSENISESVEKATDGKYQSKGKGNKKRTSENPGETKDHPVCLAETNSQISAGSSQNSSCRDDIQQSQSKETTPKKQCRTNRGKQATPKVRPLYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPDGVLCSSTIPSHYKKYTHVLLAQSRDSKEPLS-PSQALAGRFAAAQPDS-CNLEERRSVLLKTEDSRKVLEDSLLMIQCLKTSQPPAETNRKSASSPRSQKSLVPQRAEFVKRDQLVGSGSPLAEVAFNCQSESGSTGLPLPENGCGDFEISYSPLHSDEETYNCDQELDDSQQELFFTQSSKDSSL---EDVSATFENLHGPFPEEAEGIQPTAKTLAAQAGCSA-LSRGSTGNDSFQLISRTSGRLSGEDPSDTDAAFLLLSPAPSAVGGATPNCQTTKAK---PEKFHSLASRHQQQKTETSAAGSHTSLPLLLSAMSKPLEKEGGERLPLHPTQSQRRGLWSKGSGAPG---ANCACS--------------NTQRPSSAPLNKSLSTAPSSPKGSASQPSKKVMKQMDIGVFFGLPPKTQDTSPR-ERASEGPKASPVVSPSEKRPRLCKRKAQSSLSDLEFDAKNLNESQHSMELSGERAQHRRKRHKKSNSPQEGTYQGRSGHLTNNPELGAVSLRRSKAFARRTPS-RTQRGAVNISESSGGGESRR-TCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRP--------IYCSEITGSLLKKKLRVQEQYIHQLPMDTECIVDG-VKVVLLDANHCPGATMILFQLPNG-------AVTLHTGDFRADP----SMERS-LLASRK-VHTLFLDTTYCSPEYTFPSQQEAIQFAIN--TAFEAVTLNP-----------------------RALIVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEVS---------SLITTDMCNSLVHLLPMMQIN--------FKGLQNHLKKCGGKFDQILAFRPTGWTHSNNITS-----------------------------------IADITPQTKGN--IAIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVG--------------TFQSRNTMEKY----------------FKEWRLEAGY--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIC3-1", "uniprot_id": "DCR1A_MOUSE", "id": "Q9JIC3-1", "name": "DNA cross-link repair 1A protein", "aln": "MLEDT-WEEEIWEYKSKRKPKPVHPNNCSENISESVEKSTDGKHQSKG--NEKRTSENPGKTKDHKVCLAETDSQISAGSSQSSSCRDESQQSQNKETTPKKQHRTRRGKQVTPKVRPVYDGYCPSCQMPFSSLLGQTPQWHVFECLDSPPISDTECPEGLLCTSTIPSHYKKYTHILLAQSRDSKEPLGSPSDALAGLFAAAAPGSPCNLEERRSMTLKTENLRKVSDHSLLMMQYLETSQPSAEINRKNVSSPCSQTSPVPQCAEFVKRDQLVGGGSPLAEVALNSQSKSGSMGLPLPENDTDSCEISYSPLHSDEETYDIDQELDDSQQELFFTQSSKDSSLE--EDGSAIFENLHGPSPKEAEGIRPTAKSLVAQARCSA-PSEGSTLSDSFLLLSYTSNRLSQEDLPHTDAAFHLLSPA-LAVGGAASNYQTSKAKLDEPEKFLSLASSHQQQKIETSAVGNQTSLPLLTRARSKPLEKEGGKCLPLHPTQSQTRGSPRKGLGAPG---ANCACR--------------NAQKRSSMPLDKPLGTSPSSPKCSPSQPSKKVMKQMDIGVFFGLPPKRQETSLR-ESASEGPNVSPVVSPNQKRPRLCKRKAQSSLSDLEFDAKNLNESQHSVGLSGEKRQHRRKRHKTSNSPREGPCQRRSGHLMNNPELGPVSL--SKAFVRRTRG-RTQRGNMNISESSGAGEVRR-TCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRP--------VYCSEITGNLLKKKLRVQEQYIRQLPMDTECVVDS-VKVVLLDANHCPGATMILFQLPNG-------AVILHTGDFRADP----SMERS-RLAGRK-VHTLFLDTTYCSPEYTFPSQQEVIQFAIN--TAFEAVTLNP-----------------------RALVVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEVS---------SLITTDMCDSLVHLLPMMQIN--------FKGLQSHLKKCGGKYDQILAFRPTGWTHSNNITS-----------------------------------TADIIPQTRGN--ISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVG--------------SFRSRNTMEKY----------------FKEWRLEAGY--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PJP8-1", "uniprot_id": "DCR1A_HUMAN", "id": "Q6PJP8-1", "name": "DNA cross-link repair 1A protein", "aln": "MLEDI-SEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAK-EVKDHEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQHVSPKIRPVYDGYCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQSRAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDN-SVSNDPLLMTQYFKKSPSLTEASEK-ISTHIQTSQQALQFTDFVENDKLVG-------VALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSLNDLSQPISQNNESTLPYDLACTGGDFVLFPPA-LAGKLAASVHQATKAKPDEPE-FHSAQSNKQKQVIEESSVYNQVSLPLVKSLMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATILNTENLSSTPAPKYLKILPSGLKYNARHPSTKVMKQMDIGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKRSSQCKRKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLIN-TESEAVNLSKVKVFTKSAHG-GLQRGNKKIPESSNVGGSRKKTCPFYKKIPGTGFTVDAFQYGVVEGCTAYFLTHFHSDHYAGLSKHFTFP--------VYCSEITGNLLKNKLHVQEQYIHPLPLDTECIVNG-VKVVLLDANHCPGAVMILFYLPNG-------TVILHTGDFRADP----SMERS-LLADQK-VHMLYLDTTYCSPEYTFPSQQEVIRFAIN--TAFEAVTLNP-----------------------HALVVCGTYSIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEIN---------SLITTDMCSSLVHLLPMMQIN--------FKGLQSHLKKCGGKYNQILAFRPTGWTHSNKFTR-----------------------------------IADVIPQTKGN--ISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVG--------------TWKSRSTMEKY----------------FREWKLEAGY--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F457-1", "uniprot_id": "E7F457_DANRE", "id": "E7F457-1", "name": "DNA cross-link repair 1A protein", "aln": "-MSQSGSESDIWDYKPLKKNK-----KRSCKSQGSREHVTKRKKESTVQKTVKSAEKHT--DLDHQIGSNAPNNTVNSGS-------EDVNHGTVSRDVPNADSQSGR-------------GFCPVCQMPFSILVVQSQQWHVAECLDTAADNCKECPDGLQCMSTIPNHYKRYNHSQLAQSRAQNDSVQAISDFS---LNSVNNGASTSVKE--SSVDSAVNVSASSSQSSSPGDRLKGTPTKSNALLLLRSPNTEDIKKKKGWSPSVKRS----------QSQISSQEAKAKISAPG-EVRCVDSAVQTQPNEVKKELFECKDDDDYISCSPLSELP-------------------------EVDEEHRVEKSNNDRHFYSTALQED---DDSLNLFSDEDD----------DLFFDVIDQYEEHGPDKSSLDTCEKQQTSLAPESHLTASSSTGVSFHHCSTNNNSSNSQLQSPQSLVLEHLRDRISTPTHVKSLTSSFEEVNFTQTN-----------------------QESFSNQADLSATQSMAPRRTQIKAG-PSG--LKQTDIGVFFGLKPLHEK--------KAGKEVKPLVREADLQKSRRVRVSEA---------------------QGEDGKRQGRWRGKSKAPSEGSG-------VSPAVEDSVALPTQTEGKRGGRAEGRKRWNRGKATDGDPKEPKR--CPFYKKIPGTGFAVDAFQYGVVEGVTAYFLTHFHSDHYGGLKKDSAVP--------IYCNKVTSNLVKSKLKVDEQYIHVLPMNTECIVQG-VKVTLLDANHCPGAAMLLFVLPDG-------QTVLHTGDFRADP----SMERYPELQGLR-IQTLYLDTTYCSPEYTFPTQQEVVTFAVN--TAFERVTLNP-----------------------RTLVVCGTYSVGKEKVFLAVSEVLSSKVCLSKDKYNTMCCLESEDIG---------QRITTNWQSAQVHVLPMMQIN--------FKNLQTHLKKFSKKYDQLVAFKPTGWTFNQTVG------------------------------------VDDILPQTQGN--ISIYGIPYSEHSSFLELKRFVQWLRPKKIIPTVNVG--------------SWRSRKAMEGF----------------FHEWMTEPRNLSSTPCTLRSSSCGTRQ---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VND2-1", "uniprot_id": "Q9VND2_DROME", "id": "Q9VND2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNVGKIKIRSIADLQATVRVNVEPDPTPTIEN--------------------------RTPDKKRAGRTRAASTTKKVRPKTEACPIIAST------------AFKRSSKKTPLPGQMRIDSFFTSAVKNYKVKSSSSCRKVDPPLD------------------------------------KRKVSTKGRKRLFEESTTTSSAFTG-------------------------------------------KLDAKPSEKRVQPSRRAKGKENASLSEVHVIDLCSEDEQTIKRKPSAIASPCEKSSDVQATKFRTPETSMPEAKLSNSS---------------------------LDLVEISPGPNKSPTNN-------------------FYRSSP------------AAITKESPLGKNSKKGTVRKQRKPKP-------------------------------------------------------------------------------------------------CPPYKVVEGTSFCVDGFQFGEIEGVTHYFLTHFHADHYIGLTKKFCHP--------LYVSPISARLVRTFIKLDETHIHEIDVDQTLDVDG-VQVTALEANHCPGALMFFFKLSSG-------ECILHTGDFRASA----DMESLPIFWNHSNIDLLYLDTTYMNKNYDFCHQSESVDRAVDLVRAFLEKNAAK-----------------------RILIVCGSYVIGKEKIWLALAKEFTMRVWTESNRSTAVRCLNWPDLD---------SVLTEDRSGANLHVIAMGKIS--------YPSLVDYFTEFEDQYDMLLGIRPSGWEK-------------------------------------------NSKPSYGKR--ISTIGIEYSEHSSYKELERFVRFLKPKRVISTVPVGRDLYVTGEVPIRWYKYEGRASMLRTGFQPSISTFLATPKRAFAKFSADTEMFLSPVDENASKGSEDKKDDDRESVVPTNHVTIISDTPEECFQTDSKIPVKNEPLAPDTSPNSEIVAQLNAMESEIPYVEIDIKNETIAPDAVLIPRVPTEDTFQSTDCNVIGVQKSQAVVVSRLTSDASDDWLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30620-1", "uniprot_id": "PSO2_YEAST", "id": "P30620-1", "name": "DNA cross-link repair protein PSO2/SNM1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRKSIVQIR---------------------------------------------------RSEVKRKRSSTASSTSEGKTLHKNTHTSSKRQR------------TLTEFNIPTSSNLPVRSSSYSFSRFSCSTSNKNTEPVIINDDDHNS---------------------------------ICLEDTAKVEITIDTDEEELVSLHDN----------------------------------------------EVSAIENRTEDRIVTELEEQVNVKVSTEVIQCPICLENLSHLELYERETHCDTCIGSDPSNMGTPKKNIRSFISNP----------------------------------------------------------------------------------SSPAKTKRDIATSKKPTRVKLVLPS-------------------------------------------------------------------------------------------------FKIIKFNNGHEIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSWNNPDENPIKKTLYCSKITAILVNLKFKIPMDEIQILPMNKRFWITDTISVVTLDANHCPGAIIMLFQEFLANSYDKPIRQILHTGDFRSNAKMIETIQKWLAETANETIDQVYLDTTYMTMGYNFPSQHSVCETVADFTLRLIKHGKNKTFGDSQRNLFHFQRKKTLTTHRYRVLFLVGTYTIGKEKLAIKICEFLKTKLFVMPNSVKFSMMLTVLQNNENQNDMWDESLLTSNLHESSVHLVPIRVLKSQETIEAYLKSLKELETDYVKDIEDVVGFIPTGWSHNFGLKYQKKNDDDENEMSGNTEYCLELMKNDRDNDDENGFEISSILRQYKKYNKFQVFNVPYSEHSSFNDLVKFGCKLKCSEVIPTVNLN--------------NLWKVRYMTNW----------------FQCWENVRKTRAAK----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . :. : . .. . . . . . . : . . . . * * : **.*:: * : ***:***:*** **.* * :* . ::. *:. ::: *: : :: : . :.*. *:******* :::* . *******:.. :: :. ::***** . * * * . . : : : *.: *:* :****: : :.. : :: : . * : . . :* : : :*::.: :. .* .. . : ::.: *:** . . : .: ******: :: :* *: ..:*.** :. . * * : ", "identical_positions": 74, "similar_positions": 123, "identity": "5.61%" }, { "cls_id": "homologset.agr.MGI:1930075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Y6-1", "uniprot_id": "TFP11_RAT", "id": "Q5U2Y6-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGHLDDDDD-ERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDE-------ERPSFGGKRARDYSAPVNFISAGLKKGAAEEADSEDSDAEEKPVKQ-------EDFPKDLGPKKLKTGGN-------------------FKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---LQDFPVADSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKG-RVSKKLTAPQ-KELSQVKVIDMTGREQKVYYSYSQISHKHSVPDEGVPLLAQLPPTAGKEAKVPGFALPELEHNLQLLIERTEQEIIQSDRQLQYERDMVVSLSHELEKTAEVLAHEERVISNLSKVLALVEECEHRMQPHGADPLTLDECAR--IFETLQDKYYEEYRLADRADLAVAIVYPLVKDYFKDWHPLEDSNYGTQIISKWKSLLENDQLLSHSSQDLSSDAFHRLMWEVWMPFVRNVVAQWQPRNCEPMVDFLDSWAHIIPVWILDNILDQLIFPKLQKEVDNWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPVRSKLSSALQKWHPSDASAKLILQPWKEVLTPGSWEAFMLRNIVPKLGMCLGELVINPHQQHMDAFYWVMDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQR--GIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERA6-1", "uniprot_id": "TFP11_MOUSE", "id": "Q9ERA6-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGHLDDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDE-------ERPSFGGKRARDYSAPVNFISAGLKKGAAEEADSEDSDAEEKPVKQ-------EDFPKDLGPKKLKTGGN-------------------FKPSQKGFSGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---LQDFPVADSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKG-RVSKKLTAPQ-KELSQVKVIDMTGREQKVYYSYSQISHKHSVPDEGVPLLAQLPPTAGKEARMPGFALPELEHNLQLLIERTEQEIIQSDRQLQYERDMVVSLSHELEKTAEVLAHEERVISNLSKVLALVEECERRMQPHGADPLTLDECAR--IFETLQDKYYEEYRLADRADLAVAIVYPLVKDYFKDWHPLEDGSYGTQIISKWKSLLENDQLLSHSSQDLSSDAFHRLMWEVWMPFVRNVVAQWQPRNCEPMVDFLDSWAHIIPVWILDNILDQLIFPKLQKEVDNWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPVRSKLSSALQKWHPSDASAKLILQPWKEVLTPGSWEAFMLRNIVPKLGMCLGELVINPHQQHMDAFYWVMDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQR--GIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBB9-1", "uniprot_id": "TFP11_HUMAN", "id": "Q9UBB9-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGRIDDDDD-ERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDD-------ERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQ-------DDFPKDFGPRKLKTGGN-------------------FKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---MQDFPVVDSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKG-RISKKLTAPQ-KELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQSQQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMTEVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECAR--IFETLQDKYYEEYRMSDRVDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRLIWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQR--GIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DI35-1", "uniprot_id": "TFP11_DANRE", "id": "Q6DI35-1", "name": "Tuftelin-interacting protein 11", "aln": "MSMSHLYG-RRGDEEEEDGVEIEKFEVSEWDLANEFNPDRRRYRQTKEEATYGIWAEQDSDD-------ERPSFGGKRAKDYSTPVSFVSAGLRKTAAEEKAEREGSDDSDAEEA-------PPPPRAAAPKKLQTGGS-------------------FKTSQR-FAGGIRTGQDLGNWEKHTRGIGQKLLQKMGYVPGKGLGKNAQGIVNPIEAKLRKGKGAVGAYGSERTQQS---LQDFPVVDSEEEEEEEFQKELGQWRKEPGT-----AKKKPKYSYRTVDDLKAHGTRANMSMSRPA-GELAQVKVIDMTGREQKVYNSYSHMSQKHSVPEEAP------LSVSTREQKSSGFALPELEHNLKLLIELTEQDILQSARLLQHEKDTVVTLTHESDALQVRLAEEEETLGRLEQVMSLVERFEAGDK-EGDPALSLQECAK--IFEQLQTEFYQEYKTMGLGDLAVSVVHPLLKEKLRNWDPLKDCSDGLEEVGQWRAILESTLSLHSGPDTTNMDPYHRLIWEVWVPVMRTCVSQWQPRNVGPMVDCVECWAPVLPLWILDHVLEQLIFPRLQREVDNWNPLTDTVPIHSWIHPWLPLMQTRLEP-LYAPIRSKLAHALQRWHPSDSSARLILQPWRDVFTPGAWEAFMVKNIVPKLALCLGELVVNPHQQLLDPFNWVMDWECMLSVSSMVGLLDKNFFPKWLQVLCSWLSNNPNYEEITKWYLGWKGLLSENLLSHPLVKEKLNEALDIMNRAVASGLGGYMQPGARENIAYLIQTERRKDFQCELQPERREVDNSATRPPGMAAVPASVPTNFKDLVQAKAEENGIVFMPLVAKRHMGKQLFTFGRIVIYIERGVVFVQGE--KTWVPTSLQSLIDMAK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y103-1", "uniprot_id": "TFP11_DROME", "id": "Q9Y103-1", "name": "Septin-interacting protein 1", "aln": "----------------MSDNDYERFEITDYDLDNEFNINRPRGRQSRHQQIYGIWADDSEEESGGEGGTKRRGRAARKPKDYTMPVNFVAGGIQQAGKKKKKALQADDEKGSQKEGAEADQGEESDDSAASGRPAFGQNDPGSSNSSSEEERPTLSRKQPSTTFQHRSHIASERNVGAWEQHTRGIGAKLLLQMGYEPGKGLGKDLQGISHPVQAHVRKGRGAIGAYGPETAASIGGKTNKSIKVDEDVREAKEFKDQLNKWRKGSAGGAEPMERQGKRYYYKSVEEVIAKGHTSGHLLSEKLSKKLGNVRVIDMTGPEKRVLSGYHALGQAKITPEETLY---DTEATEKGSAPACVFAMPELTHNLQLLVSQCEQQIIAIDNQERECSSQQAALESEHRKLEEIVQLERNHIRTLEESLERVERLIDNPD------LSLPQAER--LFRELLVDYAAEFHEFGLADLAAGVIAPLLKRELVQWQPLENPTEPLPLIKKWRGMLQQGDAAEQQPR-NVFDPYSSLIWAGVMPSFRSSAAAWQPKEHPPMASLLDAWAPLLPSWVLDSVLEQLVLPRLVAGVQEWDPLTDTVPIDSWVLPWHAILGSKLEEAVYPQIRSKLGIALRAWSPHDRSARAMLTPWQKAFPEEEMQEFLQRYIVPKLQATLGELIINPMHQDLELWQQVWEWHELIDPMYMAQLLDRHFFPRWMQVLVVWLNQSPDYAEISRWYTGWKSMLSEPLLREPSVKEHLRRALEIMHRASDTLLQPTVTPTPPPPVPPAPVIM-------------------------MDLIHPPAQLEFKELVSQQCADLGIIFAPLPGRREMGKQIYRVGKLFCYIDRHVCMVSDGSFSNWKPVSLNHLLERSQTGIL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06411-1", "uniprot_id": "SP382_YEAST", "id": "Q06411-1", "name": "Pre-mRNA-splicing factor SPP382", "aln": "------------------------MEDSDSNTDKKFFFKKRR------IDSYNYSDEEDNNS------------------SMNSDMTYTNDALKTSSGNAPTISKLT--------------------------------------------------------------------------KTYGIGAKLLSSMGYVAGKGLGKDGSGITTPIETQSRPMHNAGLGMFSNTNSSNYHSENEDYLSSEDEVVEGIEQVKFNKTSTEVLG-----EALLNDSGDMTIVRTLRELRLAGVQLPESILKELDPLNAVPKPKKDVVVEILQELLGIEKSLEAIRQR--TSPLEVQVKEYYGQERLLSELEVTLRDESKHVSLYDKIGAILKLSDDELIDRLTSCLLRKELLIEFDLDHLEKPNDILDELTQIIELLAYRMDTTSKFLNRTQTTIFKVIYPKLKKFWEGFDMTKSKIDSAITLLLDFQQVLSFIG-CKEHIMEEFVYPKLLQELDNWELHDEVDHVSP-RIWVLDFMVLIDDKIKDTIVDKIEAKFFAYCKNWYHRESFCITN--SDIIFIKELICERRYYK-----ILCKEFLPKFLDELWERHNDPIYELEDWKEKQEWKEKDSGFFYFMKKLRSYTHYFHPKQYELMMRG-TFNNINKILYQWHLYSTVEDLHKSKWWLNW--LMNTVFEHSLPTEIELSEIRKSYNIFAMSHRYHLDKSTLDEDFDLRQGLRNLMETQVIDDISQSEQEPTYTVQNIPLGKVSSSFKDVVEDYCLEK--------------------------GYLISKIPNRYTQLPYGRDQD---CIVPLFEIRNGKK------KMEVALKHDILWVEDSS-GTFKPIYLWALDL-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: : ::* .: * *. : ..:. . . :.: .:: . : . :* *** *** .*** .*:****: .** *:::: * :.* . .: . :. ..: : ::.: . :: . . :. :* :..: . : * :. : . :.** .*: . . . * : : : .. : : . .: : : :*. : . :. . . .*: : . : :*:. .. : : . : : . * . : : : :.: .* :. : ..:: : : : : :* * : . * .: . : : :: . :: * : : . : :. :* ::. * . :.. : : . : : : .:. . * .. * :.: .: : : . : . : . .:.:* : : : *: *. * :: :.: : *.. .: * * * ", "identical_positions": 51, "similar_positions": 201, "identity": "5.72%" }, { "cls_id": "homologset.agr.MGI:1930076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2B9-1", "uniprot_id": "KS6A4_MOUSE", "id": "Q9Z2B9-1", "name": "Ribosomal protein S6 kinase alpha-4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDEDEDEG----CAVELQITEANLTG-----------------------------------------HEEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRS-KAGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVKSHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPAGSPPPGDPRIFQGYSFVAPSILFDHNNAVMADVLQAPGAGYRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEENTQREVAALRLCQS----HPNVVNLHEVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQ-SPAEPMQTP--------CFTLQYAAPELLAQQ---GYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAA--EIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRSSSWLQDGS---------------ARSSPPLRTPD----------------VLESSGPAVRSGLNATFMAFNRGKREGFFLKSVEN-----------------------------------------APLAKRRKQKLRS------------------AAASRRGSPVPASSGRLPASAAKGTTRRANGPLSPS------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSB7-1", "uniprot_id": "D3ZSB7_RAT", "id": "D3ZSB7-1", "name": "Ribosomal protein S6 kinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDEDEDEG----CAVELQITEANLTG-----------------------------------------HEEKVSVENFALLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRS-KAGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVKSHLFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPAGSPPPGDPRIFQGYSFVAPSILFDHNNAVMADVLAAPGAGYRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEENTQREVAALRLCQS----HPNVVNLHEVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQ-SPAGPMQTP--------CFTLQYAAPELLAQQ---GYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAA--EIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRSSSWLQDGS---------------ARSSPPLRTPD----------------VLESSGPAVRSGLNATFMAFNRGKREGFFLKSVEN-----------------------------------------APLAKRRKQKLRS------------------AAASRRGSPVPASSGRLPASASKGTTRRANGPLSPS------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75676-1", "uniprot_id": "KS6A4_HUMAN", "id": "O75676-1", "name": "Ribosomal protein S6 kinase alpha-4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDEDDDES----CAVELRITEANLTG-----------------------------------------HEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRS-KTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQS----HPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQ-SPGVPMQTP--------CFTLQYAAPELLAQQ---GYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAA--EIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGS---------------ARSSPPLRTPD----------------VLESSGPAVRSGLNATFMAFNRGKREGFFLKSVEN-----------------------------------------APLAKRRKQKLRS------------------ATASRRGSPAPANPGRAPV-ASKGAPRRANGPLPPS------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCZ3-1", "uniprot_id": "A0A8M2BCZ3_DANRE", "id": "A0A8M2BCZ3-1", "name": "Ribosomal protein S6 kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGDSSGSSGEDSDRETRRKVCTVKHEITNANLTG-----------------------------------------YTEKVGMENFELLKVLGTGAYGKVFLVRKISGHDKGKLYAMKVLKKAAIVQKAKTAEHTRTERQVLEHIRQSPFLVTLHYAFQTQTKLHLILDYVSGGEMFTHLYQRDHFSEDEVRIYVGEIILALEHLHKLGIVYRDIKLENILLDSDGHVVLTDFGLSKEFLEEEKERTYSFCGTIEYMAPEIIRG-KSGHGKAVDWWSLGILMFELLTGASPFTLEGERNSQSEVSKRILRCEPPFPSIIGPLAQDLLRKLIVKDPHKRLGSGPRGAEEIKGHPFFKGLNWSDLAEKKVQSPFRPELRDELDVGNFAEEFTGMEPVYSPASTPPSTD-RLFQGYSFVAPSILFNKN-VVMADVLDAHVNVDRPGSATVQRSAMLKESQFFQHYELCLQGSPLGEGSFSVCRKCRHKQSGQEYAVKIVSRRMEAMTQREIAALRQCES----HPNIVTLHEVYTDQYHTYLVMEMLRGGELLERIRKRKMFAEWEASQLMKSLVSAVSYMHEAG-VVHRDLKPENVLFADESDESVLKVIDFGFARLFPAGSGSAPLQTP--------CFTLQYAAPELFHSS---GYDQACDLWSLGVILYTMLSGQVPFQSEKKVMTSSHAA--DIMHKIKEGDFSLDGEAWKGVSEEAKDLVRGLLTVDPERRLKLSALKENAWLQGGG---------------VMSSTPLCTPD----------------VLESTGPTVRTYVNATYKAFNRGKREGFFLKSVDN-----------------------------------------APLAKRRKMKMTST-----------------GVETRRSSSSSSSSSSSSASHSKTQNCQSLNPHEDPKL----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3I5-1", "uniprot_id": "JIL1_DROME", "id": "Q9V3I5-1", "name": "Chromosomal serine/threonine-protein kinase JIL-1", "aln": "MSRLQKQNYEILSGTSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNSNSETMTNGKKSKLNTEGSGSGSGKTLNYNNNNNNNNSISATNGQYTNSSSKTTSASARDYTYRETISPPTPPSPPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDEPNGIEIDESSSSLSKAKSNNAAAAAAAAAAAAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPED-PECDAPPSRIRLFRGYTYVAPEHLEQMR---------------RDNHCEIQYFNTGLQNIPCRPDDLELG-TRTSNGAYGTCHFVVDSSTDLVFLAKIIP--LSKFRPSEVDALISCALDTTNHKNIVSYHGTFREKCETWIVMEYLSGPELTASIR----MDEDSCREIFLQLVMAVRHIHSKH-FIHGDLKPENIMFEN-REDRTVKLIDFGSACYNNR--FKSWKDKP--------RYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILDSEWLQYGSNDPDVDIILPQQMVVDLSEDTMEQPTGGMFDDQQQLEFMHDKSAEDEGITLVSEPMDTTVATHESRRNAAAFSSVVAPTTDDEIVHERFDPAFEVQADFYGFDENAPPLPLPEEYYSELPLPEEDRQYIPPPPALIPVEPETTFRRPRTRQQRRTESQLVQPVSVATYEDSKASLRVLMQQLPPPGDNVVARIPKRTHRVVRTLPPTFGTTKREENFYGFSKTAISWRKTRASWRHFCLLINGVQQVLKVRFKKARRVYCLPHIKEEKLDHAYEKPLTFPRPKAQLKRTKREPKVPRPPTRVQPERARAMRQLYQFQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38070-1", "uniprot_id": "YPK3_YEAST", "id": "P38070-1", "name": "Serine/threonine-protein kinase YPK3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIFSLDEELHRVSLDDKKNDIKVDYSS--AIYNDINHEQ-----------GSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRR---------------------------------------------FSITGSDAMRTNTNRLSITPQDIISSNIG--ENELSRNLHDFKPVRVLGQG-----AYGKVLLVKDVNTSKLYAMKQLR-------------------------------------------------------------------------KAEILISQTATDS---KREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEH------------------------PNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKG-VVYRDLKPENCLLNQ---RGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGK---AYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQ-----------QNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNKP---------------TKSKKKKSGAAR--------------TSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVIT----------------------------------------DLELAENFDTEFTSMS---------------YEETYTDSKPININSVSKSPDMFKGFSYKASGSYLEKYF----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ** . . * : :*: . ::..: : : .. : * :::*.: . : *:.: : : :. : : * *: . ::: .: . :. :. .:: .: .* : ** . :.:.:: * : . : :. : : .:. . .: : :* *:*. . :: . ::::: : * ** :: : * .: *: .:* .:: ****** : : : : *** : : * :*..**:: *. * :.** ** ** *: *: . . . * :.:: * :. * .:. . : *. . . . : : : : .* *.:. : . . . * ", "identical_positions": 52, "similar_positions": 144, "identity": "4.19%" }, { "cls_id": "homologset.agr.MGI:1930079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0R9-1", "uniprot_id": "FADS2_MOUSE", "id": "Q9Z0R9-1", "name": "Acyl-CoA 6-desaturase", "aln": "------MGKGGNQGEGSTERQAPMPTFRWEEIQKHNLRTDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESLAWFILSYFGTGWIPTLVTAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHVVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMISRRDWVDLAWAISYYMRFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMN-HLVMEIDLDH-YRDWFSSQLAATCNVEQSFFNDWFSG-HLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALIDIVSSLKKSGELWLDAYLHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z122-1", "uniprot_id": "FADS2_RAT", "id": "Q9Z122-1", "name": "Acyl-CoA 6-desaturase", "aln": "------MGKGGNQGEGSTELQAPMPTFRWEEIQKHNLRTDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESIAWFILSYFGNGWIPTVITAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHIVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIRRRDWVDLAWAISYYARFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMN-HIVMEIDLDH-YRDWFSSQLAATCNVEQSFFNDWFSG-HLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIVSSLKKSGELWLDAYLHK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95864-1", "uniprot_id": "FADS2_HUMAN", "id": "O95864-1", "name": "Acyl-CoA 6-desaturase", "aln": "------MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMN-HIVMEIDQEA-YRDWFSSQLTATCNVEQSFFNDWFSG-HLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DEX7-1", "uniprot_id": "FADS2_DANRE", "id": "Q9DEX7-1", "name": "Acyl-CoA 6-desaturase", "aln": "------MGGGGQQTDRITDTNGRFSSYTWEEVQKHTKHGDQWVVVERKVYNVSQWVKRHPGGLRILGHYAGEDATEAFTAFHPNLQLVRKYLKPLLIGELEASEPSQDRQKNAALVEDFRALRERLEAEGCFKTQPLFFALHLGHILLLEAIAFMMVWYFGTGWINTLIVAVILATAQSQAGWLQHDFGHLSVFKTSGMNHLVHKFVIGHLKGASAGWWNHRHFQHHAKPNIFKKDPDVNMLNAFVVGNVQPVEYGVKKIKHLPYNHQHKYFFFIGPPLLIPVYFQFQIFHNMISHGMWVDLLWCISYYVRYFLCYTQFYGVFWAIILFNFVRFMESHWFVWVTQMS-HIPMNIDYEK-NQDWLSMQLVATCNIEQSAFNDWFSG-HLNFQIEHHLFPTVPRHNYWRAAPRVRALCEKYGVKYQEKTLYGAFADIIRSLEKSGELWLDAYLNK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19967-1", "uniprot_id": "CYB5R_DROME", "id": "P19967-1", "name": "Cytochrome b5-related protein", "aln": "MVIEEWKKSGIATKFPTYRNSALITTHSWQKGKRQDDGAEGLWRINDGIYDFTSFIDKHPGGPFWIRETKGTDITEAFEAHHLTTAPEKMIAKYKVRDAAEPRIYTLTLEEGGFYKTLKERVREQLKTIDKRPKK-------KSDLIHLGLVVSLYLLGIASAKYNSLLALVLASVALCWTVIVSHNYFHR------RDNWQMYAFNLGMMN--FAAWRVSHALSHHIYPNSY-FDLELSMFEPLLCWVPNPHIKS-KLMRYVSWVTEPVAYALAFFIQMGTRIFYSLRHTNILYWHDLLPLTIPIAIYLGTGGSLGIWICVRQWLAMTSIASFSFCLIGLNAAHHDPEIYHEGDANREDRDWGLFQVDTIIDRGDLKWSQFLVLTHFGDHVLHHLFPTLDHGLLPALYPVLYQTLDEFKGHLRECNHIEHMIGQHKQLLRIEPNPRAPGAGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . ..:. *:: ::: : :: :*:.:.: :**** : . * * *:** *.* * : . . : :.. . ::: : . .: ..:: : :. : : :... :::. .: :.: . : :.*:: * * :: * :* :: * * : :.** ** : * ::. :. :: :* . * ::::.: : : : : . * .:: : * :: * : : : : .: * . : .:: . .: : * : :** *: : : : :.::: *:. :: ******: : * : :. . :* : . .* : . *", "identical_positions": 48, "similar_positions": 144, "identity": "10.6%" }, { "cls_id": "homologset.agr.MGI:1930088", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZM3-1", "uniprot_id": "CLCF1_MOUSE", "id": "Q9QZM3-1", "name": "Cardiotrophin-like cytokine factor 1", "aln": "-----MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPG-PGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETL--PRATVNLEVWRSLNDRLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMATLGYP-LP-------------------------------------------------------------------------------------------------------------------------------QPLPGTEPAWAPG-----------------------------------------PAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAASVTLHLEAHGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EKG3-1", "uniprot_id": "F7EKG3_RAT", "id": "F7EKG3-1", "name": "Cardiotrophin-like cytokine factor 1", "aln": "MQPTAWEPEAGDSWGMLACLCTVLWHLPAVPALNRTGDPG-PGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETL--PRATVNLEVWRSLNDRLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMATLGYP-LP-------------------------------------------------------------------------------------------------------------------------------QPLPGTEPAWAPG-----------------------------------------PAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAASVTLHLEAHGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBD9-1", "uniprot_id": "CLCF1_HUMAN", "id": "Q9UBD9-1", "name": "Cardiotrophin-like cytokine factor 1", "aln": "-----MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPG-PGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETL--PRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYP-LP-------------------------------------------------------------------------------------------------------------------------------QPLPGTEPTWTPG-----------------------------------------PAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6T6-1", "uniprot_id": "A0ACD6B6T6_DANRE", "id": "A0ACD6B6T6-1", "name": "Cardiotrophin-like cytokine factor 1", "aln": "--------MCPWKVGQVAVLLLLAVMVGNAQVLDRTLILSNERSSIERTYELTKYLDHQLKEIRDTYLSYLGPPFSHPGFSPPRPNSSSLSVPSAATRVDLWRGLENGARLAQNQHAYSILLCAVRELARSTLCPYLQSSLLHFCSGLSGLLGSISGLMNALGYTNLPSSAGYATPAQGYAPAMSSQFQGVSENSPAPLRSYVPRNQGAKTVSGVREGTTRADLKRDREKERAERGRRGRRKEGESWVAKEEGEKEEGMERWGKRRRLLSMDEEKTIKLNNMNYTSLKFGDGYRKQPLLFSTPSLHPRRSVRSIPSSHSGLSPLSLLYQYGGPVSEVHTLLAAPVLSSHPTANDFSRKVEGFWVLRELQSWLWRSAKDFTRLKKRLRV--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :* * : : . .*:** . .**::**:**:**:***:.: .***.******..*.*.*** .:.:* * *:. :::**.*:: **:** .*** *** :* * *.: . *: ** ***:.*.******:*:* :***. ** *** : *: * *: .** :*::.**:*:***:*********.****::: ", "identical_positions": 98, "similar_positions": 65, "identity": "24.38%" }, { "cls_id": "homologset.agr.MGI:1930089", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JV99-1", "uniprot_id": "A0A0G2JV99_RAT", "id": "A0A0G2JV99-1", "name": "Germinal-center associated nuclear protein", "aln": "MNPVNPFSGQQPGAFAVSSSATG----TFQTKSPFR---FGQPSLFGQNNQAS-KSLGFSQVPSFATPSGGSHSS----------SLPAFGLTQTSSVGLFS-GLESTPSFAATSGPS-SSSVPGN-TAFSFK---SASSVG-VFSSGPTFGPETGDVAG------------SG-----FRKTEFKFKPLENAVFKPILGAESEPEKTQSQIASGFFTFSHPVSSGSGG-----LTP----FSFPQVTNS---SATSSSFIFSKPVTSN--TSAFAP----ALSNQNIEEEKRGPKSVFGGLNSSFSTFPMASPGSLGEP------FPTNKTSIRQGGE-EAISQVESHPALMKGLKRKEDQDRSPRRHCHEAAEDSDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQEVFKSNKEAGRLGSKESKKDSGFVESGESDHVAIPGGSQSTLVTSRLPAVNKEEETEGRDEKEDSLRGTSVRQSKR-SESTDSLGGMSSLELTAIQCKNIPDYLNDRAILEKHFSKIAKVQRVFTRRSKKLAVIHFFDHASAALARKKGKGLHK-DMAIFWHKKKISPSKKPFSLKEKQ--LGEGEASQGIEDSPFQHSPLGKPIVRPATGSLLNKSSPVKKPGLLKIHQFEAD-PFDSGSEG-----SEGLGSCVSSLSTLIGTVADTSEEKYRLLDQRDRIMRQARVKRTDLDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVP---GTDQVDHAAAVKEYSRSSADQEEPLPHELR-----PSAVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDP----LTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRN-------KGVFCASEAEFQGYNVLLNLNKGD------------ILREVQQFHPDVRNSPEVDFAVQAFAALNSNNFVR--FFKLVQSASYLNACLLHCYFNQIRKDALRALNVAYTVSTQRSTVFPLDGVVRMLLFRDCEEATSFLNYHGLTVADGCVELNRSAFLEPEGLYKARKSVFIGRKLTVSVGEVVNGGPLPPVPRHTPVCSFNSQNKYVGESLATELPISAQRSGGD-----------SAGGGRGEEVEAEVDVPPLAVLPQ--LPPAPSATPVPHVQPLTQAVTPSLFQAS-TQPEVLLPKPVPVYSDSDLVQVVDELIQEALQVDCEEVS-SAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSMERQRVEEEKRRAEEERLKQERELMLTQLSKGLAAELTELTVTECVWETCSQELKSAVETDQKVRVARCCEAVCTHLVDLFLAEEIFQTAKETLQE-LQCFCKYLQRWRGAVAARKKLRRQMRAFPAAPCCVDVNDRLQALVPSAECPITEENLAKGLLDLGHAGKVGISCTRLRRLRNKTAHQMKVQHFHQQLLSNAAWAPLDLPSFVAEHLPVKQKRIFWKLVLVLPDGEEQTPESPGRILENWLKVKFTGDGSLVDDTRDNAGDIQTLSVFNTLSSKGDQTVSVNVCIKVARGTLSDSALDAVETRKD--LLGASGLMLLLPPKVKS-------EDVAEEDLYWLSALLQLKQLLQAKPFQPALPLVVLVPSSRGDSTGKGVEDGLMLQDLISAKLISDYIVVEIPDFVNDLHGTVKVSGAVQWLISRCPQALDLCCQTLIQYVEDGISREFSGRFFHDR-RERRLGSLASQEPSAIIELFNSVLQFLASVVSSEQLGDISWPVTEFAEVGGSQLLPHLHWNSPEHLAWLKQAVLGFQLPQMDLPPPAALWLPVCSMVIQYTSQIPSSCRTQPVLRSQVESLLCRTYQKWKSKSLCPGQQSGPSVAEIPWDDIITLCINHKLRDWTPPRLPVTLDALSEDGQICVYFFKNRLRKYTVPLSWEQARMQTQRELQLSQGCSGIKS-----------------------------FHP-TSSFPTPLLHGRHKGKKKEDGGREG-SLSTEDLLRG------------------------------------------ASAEELLAQCLNNSLLEEREENKRFEDQLQQWLSRDSQAFTESARLPLYLPQTLVSYPDAIKTQTK---VKTSTSPQNAGTGDHVRFSEASDTSLTEKLKHLERLIQSSRAEEAASELHLSALLDMVDI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUU9-1", "uniprot_id": "GANP_MOUSE", "id": "Q9WUU9-1", "name": "Germinal-center associated nuclear protein", "aln": "MHPVNPFGGQQPSAFAVSSSTTG----TYQTKSPFR---FGQPSLFGQNSTPS-KSLAFSQVPSFATPSGGSHSS----------SLPAFGLTQTSSVGLFS-SLESTPSFAATS----SSSVPGN-TAFSFK---STSSVG-VFPSGATFGPETGEVAG------------SG-----FRKTEFKFKPLENAVFKPIPGPESEPEKTQSQISSGFFTFSHPVGSGSGG-----LTP----FSFPQVTNS---SVTSSSFIFSKPVTSN--TPAFAS----PLSNQNVEEEKRVSTSAFGSSNSSFSTFPTASPGSLGEP------FPANKPSLRQGCE-EAISQVEPLPTLMKGLKRKEDQDRSPRRHCHEAAEDPDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQEVFKSNKEAGRLGSKESK-ESGFAEPGESDHAAVPGGSQSTMVPSRLPAVTKEEE-ESRDEKEDSLRGKSVRQSKRREEWIYSLGGVSSLELTAIQCKNIPDYLNDRAILEKHFSKIAKVQRVFTRRSKKLAVIHFFDHASAALARKKGKGLHK-DVVIFWHKKKISPSKKLFPLKEK---LGESEASQGIEDSPFQHSPLSKPIVRPAAGSLLSKSSPVKKPSLLKMHQFEAD-PFDSGSEG-----SEGLGSCVSSLSTLIGTVADTSEEKYRLLDQRDRIMRQARVKRTDLDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVP---GTDQVDHAAAVKEYSRSSADQEEPLPHELR-----PSAVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDP----LTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRN-------KGVFCASEAEFQGYNVLLNLNKGD------------ILREVQQFHPDVRNSPEVNFAVQAFAALNSNNFVR--FFKLVQSASYLNACLLHCYFNQIRKDALRALNVAYTVSTQRSTVFPLDGVVRMLLFRDSEEATNFLNYHGLTVADGCVELNRSAFLEPEGLCKARKSVFIGRKLTVSVGEVVNGGPLPPVPRHTPVCSFNSQNKYVGESLATELPISTQRAGGD-----------PAGGGRGEDCEAEVDVPTLAVLPQ--PPPASSATPALHVQPLAPAAAPSLLQAS-TQPEVLLPKPAPVYSDSDLVQVVDELIQEALQVDCEEVS-SAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSMERQRLEEEKQRAEEERLKQERELMLTQLSEGLAAELTELTVTECVWETCSQELQSAVEIDQKVRVARCCEAVCAHLVDLFLAEEIFQTAKETLQE-LQCFCKYLQRWREAVAARKKFRRQMRAFPAAPCCVDVNDRLQALVPSAECPITEENLAKGLLDLGHAGKVGVSCTRLRRLRNKTAHQIKVQHFHQQLLRNAAWAPLDLPSIVSEHLPMKQKRRFWKLVLVLPDVEEQTPESPGRILENWLKVKFTGDDSMVGDIGDNAGDIQTLSVFNTLSSKGDQTVSVNVCIKVAHGTLSDSALDAVETQKD--LLGTSGLMLLLPPKVKS-------EEVAEEELSWLSALLQLKQLLQAKPFQPALPLVVLVPSSRGDSAGRAVEDGLMLQDLVSAKLISDYIVVEIPDSVNDLQGTVKVSGAVQWLISRCPQALDLCCQTLVQYVEDGISREFSRRFFHDR-RERRLASLPSQEPSTIIELFNSVLQFLASVVSSEQLCDISWPVMEFAEVGGSQLLPHLHWNSPEHLAWLKQAVLGFQLPQMDLPPPGAPWLPVCSMVIQYTSQIPSSSQTQPVLQSQVENLLCRTYQKWKNKSLSPGQELGPSVAEIPWDDIITLCINHKLRDWTPPRLPVTLEALSEDGQICVYFFKNLLRKYHVPLSWEQARMQTQRELQLSHGRSGMRS-----------------------------IHPPTSTFPTPLLHVHQKGKKKEESGREG-SLSTEDLLRG------------------------------------------ASAEELLAQSLSSSLLEEKEENKRFEDQLQQWLSQDSQAFTESTRLPLYLPQTLVSFPDSIKTQTM---VKTSTSPQNSGTGKQLRFSEASGSSLTEKLKLLERLIQSSRAEEAASELHLSALLEMVDM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60318-1", "uniprot_id": "GANP_HUMAN", "id": "O60318-1", "name": "Germinal-center associated nuclear protein", "aln": "MNPTNPFSGQQPSAFSASSSNVG----TLPSKPPFR---FGQPSLFGQNSTLSGKSSGFSQVSSFPASSGVSHSS----------SVQTLGFTQTSSVGPFS-GLEHTSTFVATSGPS-SSSVLGN-TGFSFK---SPTSVG-AFPSTSAFGQEAGEIVN------------SG-----FGKTEFSFKPLENAVFKPILGAESEPEKTQSQIASGFFTFSHPISSAPGG-----LAP----FSFPQVTSS---SATTSNFTFSKPVSSNNSLSAFTP----ALSNQNVEEEKRGPKSIFGSSNNSFSSFPVSS-AVLGEP------FQASKAGVRQGCE-EAVSQVEPLPSLMKGLKRKEDQDRSPRRHGHEPAEDSDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQDVFKSNKEVGRLGNKEAKKETGFVESAESDHMAIPGGNQSVLAPSRIPGVNKEEETESREKKEDSLRGTPARQSNR-SESTDSLGGLSPSEVTAIQCKNIPDYLNDRTILENHFGKIAKVQRIFTRRSKKLAVVHFFDHASAALARKKGKSLHK-DMAIFWHRKKISPNKKPFSLKEKK--PGDGEVSPSTEDAPFQHSPLGKAAGRTGASSLLNKSSPVKKPSLLKAHQFEGD-SFDSASEG-----SEGLGPCVLSLSTLIGTVAETSKEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVVP---GTDQVDHAAAVKEYSRSSADQEEPLPHELR-----PLPVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDP----LTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRN-------KGVFCASEAEFQGYNVLLSLNKGD------------ILREVQQFHPAVRNSSEVKFAVQAFAALNSNNFVR--FFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTIFPLDGVVRMLLFRDCEEATDFLTCHGLTVSDGCVELNRSAFLEPEGLSKTRKSVFITRKLTVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELPVSTQRPGSD-----------TVGGGRGEECGVEPDAP-LSSLPQSLPAPAPSPVPLPPVLALTPSVAPSLFQLS-VQPEPPPPEPVPMYSDEDLAQVVDELIQEALQRDCEEVG-SAGAAYAAAALGVSNAAMEDLLTAATTGILRHIAAEEVSKERERREQERQRAEEERLKQERELVLSELSQGLAVELMERVMMEFVRETCSQELKNAVETDQRVRVARCCEDVCAHLVDLFLVEEIFQTAKETLQE-LQCFCKYLQRWREAVTARKKLRRQMRAFPAAPCCVDVSDRLRALAPSAECPIAEENLARGLLDLGHAGRLGISCTRLRRLRNKTAHQMKVQHFYQQLLSDVAWASLDLPSLVAEHLPGRQEHVFWKLVLVLPDVEEQSPESCGRILANWLKVKFMGDEGSVDDTSSDAGGIQTLSLFNSLSSKGDQMISVNVCIKVAHGALSDGAIDAVETQKD--LLGASGLMLLLPPKMKS-------EDMAEEDVYWLSALLQLKQLLQAKPFQPALPLVVLVPSPGGDAVEKEVEDGLMLQDLVSAKLISDYTVTEIPDTINDLQGSTKVLQAVQWLVSHCPHSLDLCCQTLIQYVEDGIGHEFSGRFFHDR-RERRLGGLASQEPGAIIELFNSVLQFLASVVSSEQLCDLSWPVTEFAEAGGSRLLPHLHWNAPEHLAWLKQAVLGFQLPQMDLPPLGAPWLPVCSMVVQYASQIPSSRQTQPVLQSQVENLLHRTYCRWKSKSPSPVHGAGPSVMEIPWDDLIALCINHKLRDWTPPRLPVTSEALSEDGQICVYFFKNDLKKYDVPLSWEQARLQTQKELQLREGRLAIKP-----------------------------FHPSANNFPIPLLHMHRNWKRSTECAQEGRIPSTEDLMRG------------------------------------------ASAEELLAQCLSSSLLLEKEENKRFEDQLQQWLSEDSGAFTDLTSLPLYLPQTLVSLSHTIEPVMK---TSVTTSPQSDMMREQLQLSEATGTCLGERLKHLERLIRSSREEEVASELHLSALLDMVDI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q712-1", "uniprot_id": "F1Q712_DANRE", "id": "F1Q712-1", "name": "Germinal-center associated nuclear protein", "aln": "MNPSNIFGRPQAAFQAPNTNQSGNLFQTFAQQKPTQGVSFGQPSAFSQPAFVQPTPQPPVFTPTFGQTGGLSQGSGQTSSFSFLGTHPAFGQPSLGQGGTLGFGQPPPPSYSQATGQT-QNSAFGQPSAFSLPSYVSQSSST-SFSSTVTSQPSFGQLSGLPVPAATSISSISGRAENPTGGNQFSFKPPNEAVFKPIFSVSPEPTSTNMSSASETAGSSKVVDNSSGGSLFSCVKPSALGFSFSQPAAAPSVSLSNSNFSQKETVGGGGSSIQFTFSQPANPSSSSTSASQPTTPSTFSFTPQSLQPQSDTKVPAFGGTGIGPFAFGVPKTVRTEDKTGDGQSSGGETAFVSFGMKRKEEPADAAKSDPSETGAD------GPRQPAKRPLLRSRVMAGGLFRVAMSDVLKS--KVSPVKREDNLPERPDPPGPSSDLATALLRPQASLVSKKAEDVSVQPEPQTRASG---------RRAAR-KESTDSLGGLSPTDATVIQCKNIPSNLNRKDLLMQHFGHFGKVLRVYSKPQKNLAVVHFQDHTSAAKAKKKGKLFQRNEIQIFWQRKKQSPGDKPARPSEIKDVIEDPESASALLQSPPIHKPLPRANPISMSGSLT-KGSPIKKSSIAKTLQFESEGPFESVSEER--SIERPINILPSVLQPLVGQVAECAEERYRLLEQRDKILRQARPKRTDLDMSKVFVGTCPDMCPEKERYMRETRNQLSVFEVVP---DTEKVDHYAAIKEYSRSSADQEEPLPHELR-----PLPVLSMTMDYLVTQIMDQGEGNCRDWYDFVWNRTRGIRKDITQQHLCDP----ETVSLIEKCTRFHIHCAHHLCQEPMMSFDAKINNENMTKCLQSLKEMYQDLAT-------KEVYCPKEAEFRQYNVLVKLNDGD------------ILREVQQFRKEIRESPEVTFAVQVFAALNSNNFVR--FFKLVSAASYLSSCILHRYFNQVRRQALKILNVAFTVGSQRSTIFPVEDFVRMLMFRNATEATEFIQQYGLTVSDGMVELSRTAYQEPDYSLPQKKSVAIEKKRTVLIGEVVNGGPLPNPPQHSPVCSFDSNNKYTGDGLSSEPPPAVLKAPAERQIFMEPEPRPQVKTRLLAEPRLFMGLSEPVKADDTEETGEKSQTAESTLPVVQQPIFPPILAPQPVRPPSPPPKPEPTYTDQDIMAEVDAVVNEVLEAEVSDVT-RSAAEYVSAALSASDSELEIVVSEVLHQLLREVSTSEIIAEKERIAEEKRKEEEARRK---EAFLQQFSAELCAKISDEVLTESIRATAEAEIRLALEEKAAY-IARCTAEECESIIEETLAEEVASIAQVILDEGLRHIRKFIKRWRDVVAVRRQLKRQMRGFPAAPGCVDPQFKLKALVPSAPSNHCLDLLAQGMVNLGNSGNMAVSCTSLLRMRQEAVHQMKVSYYYNLLMSERVWMPLDLPTLVAESTPNAPDRIFWKATLLMPSSCDSDITFASRILTDWLEVKLGGGNESEESEKQSKGQVKTLCVSHSLTNIRGQTHEVYISVKACHGPLSAEDQCLLEEQKE--LHGTNALLMLLPPVNSAGQGEEEEEEEEEEDLPLLSALLQLRQVQQASCWHSPLPLAVVVAG--NQIGDQGLEQALLLDMLVKDGLISEYIFVHIPATLNDLQGSEQMSHVVRWLSARSPASPALSSQTLLQVVELGLCREFYSRLQEDK-LDRKNAGLPSQHPEPIVELCNSVLSFLSGVVSSEHLSALCWPPPEFSLPENSELIPHQAWNSPEHLQWLRRSILSRQLPEWDLPPVDASWPHLCASIFQYVSQIPTSPLSQPILMSRLENLLRRVNYQHADED--DYEKAGPSFHEIPWDDIICLCVEHRMKDWSLDTL-VAKDALTDDGEILVYFNKDSLKSFQPPDIWIEAVKQTYQEKRQASEVCKVKHSPATRLYLRQKLFQSHIDIEERPTVEDTAQIPIEQKFKQMLSSLRDMNAESQRIGEQTQHRAGENPLRRSSFPLALRKHPAAGTAHIQETDVVELVGKVSSDRKMNRMFAPDSTQSPIMERLQHTLSTVQEMNAEGQRIGEQIRRRIEADALSSASLPLFLPSTLLSSPPLVLTTSKRPSAAVHIQEMDDLDKIASRNDKSRPVPLFQRFEDLKRELSSQREEERACGLKLNCLLDIVDN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U3V9-2", "uniprot_id": "XMAS_DROME", "id": "Q9U3V9-2", "name": "Protein xmas", "aln": "------MAEPRPGGYNYKTLLCRNIPELFLDKYVAR----SHFGRFGTLVNFVLRPRRMTCTVSYASEDEAARALLDGASFQGHLFDISYADNETAPAQKTEEWVDPDIQAELSALQSGWRNEYGSGKPIKKPQNGSSGSGGSSMLPAIPVGPATAPVSRDRTPAQLRDLENMMRRPAHTSEEKFSVLDARDKLLRLNRTQHKLSGATQGHCADMCPEKERVLREFQRQVAYYELQPGSDELICHERALKQYSRSSADQETPLPHELRNETALHMTMS--YLMHEIMDISERQDPQSHMGDWFHFVWDRTRSIRKEITQQELCSLGAVKLVEQCARFHIHCAARLVDADPSVFDSKINAENLTKCLQTLKYMYHDLRIKGVPCPKEAEFRGYIVLLNLADANFLWDIGQLPAELQSCPEVRQAIQFYLALQDTNFVRFFQLLADKDTSYLSACILVNYFTRLRVLGLHRLIQAYR------SPRKDEVSSLPLSYIAELLSFASEQEAADFVQHYGLQINEAGRVVLSRMHTVETEYKLPRQYELVEVKRVKSVGEVVSGEPLPPRDLYLNHRPHNSFDDYGMLKSIAWTAKDQLAGMQQEEMQPQMPSQPPAVSKHSDTLFKVPMQPDGTAAGFGVFAAAAVPPASSIDGFSFVLPKSRAQEFQEQAPATQQRRAQEEAKHQALQVAIAAAKKREAELMAIHEAKVAEAERVRQQKLRERQEQQRRQQQELEEQRQREQEKLQLEKERQLKLEQLFFVQQQEREAHKQTRTLELYQEIFQDTLAEICQSEFMSHSRACRSYESMLDSITRDLVERQMEQSIYELGVMRVCIRRWRKYRRTQQEKDTLFNQLPLSFGAENPEGVVNKRSMEDSLRLSRRYRLGEPCDYGKLLAGLEEHSWLKLDLWHVLDKCLPVAQPGARRFYKLLISLSGGQEGLQLNCDLDRGLLQQPQSPDARFVDGGYIRGFSQGIGLSVMKIRDDDHDWKATDLAEANGIICLIGLDDIRLLPDRLKPLLQASRCHDVAVIVQHPANTAFVQPDIPLQELCLRSFNIFRLRKSGNNRQRLMIALESAVKFLAKATERKRVGHLHQVETREYLLVNLGSELFRRLKYAAEH-----------DTAIRSDTQLNPQRCVDLFNEAVHRLQLVAGEDLSDWPQFPEELRVFVQPLPIESSLNTNRLEHFEPGWHLPERRQRIVQLLERCKLPKMPVLPRSSSLAEAQCQWVLDYAQISQQEDCVEQIALQAIKILQYDTDDYLNFVEYLAGERMQYILRQERNPPQGIVYNTKTLKRRFLSAWYYEFREPQIYEPVPAEENAQMLEK-QPSSQAEVQQLDFDEITSKAEAVLKR-FHQRQDERHTLRELNRSHKSRKRRDASDHKHAMSSLVSALKAARSDYQGKSSAVCRLVAQMVEADQVKYQWTPNLTSLIDRKDASTRHQWRPHVNHSTRHARKLPVQSISFLSRCLAKKGEHAGLTSCVLSVKTRYAPKTLHGRELLIWRQSSMRPLLLPSSNLWTGVLSKRHYVPRLRPAEEDEEVERRAVPQLRITKEQSEEEEHQLQRRKDGSRLRNECSEFYLPMGEQD-------YSEREEENRGHRQAYVPSELMTPELATKWQTTSVTDRDRQLLNLEQQMKTQPSVRMTTQTWFSGNHRRYRSRRSGAKRYHVVSELEGWRRSSNHQPVPVFQGQPGEQEHLRHASHKASARSMPDGQERCQMVWEQKKRSPWHRTEVTNSNKVRMPRIRAAKSAVMMAQEARNKHHRLITKKLVYRPRRTVNAVQAEETEDQDTHHRHHGGGQKMSKRAPERALLKQHLADLLAVSKPEDSFRIGYQPNAPTRQLLEQGKCYVSLRREQFIHLHPVRPNSLILAVNLEVKES--PRQPVTTLHR-RDGAKRPRLVEDVVKPSLITVIRQSAATWDHNGRKVPAKKSNLVG-------------------------MPSKEHAYQRRLVRNTSTLEAIVKAQAKPRSEPKSPSSATDYHR-------------------------------------------VASQKLPHVTSKADISKAADPFKDLDKPRIKEKEVASSWKQAYVVRSKMYDAITPYRRRAYPGKKCITKDKTDGYFLAKRSSAAAAGSSKKVKPPKQPVVSPKVQVPSVLHKKKSRESLGPQTTKTGKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46674-1", "uniprot_id": "SAC3_YEAST", "id": "P46674-1", "name": "Nuclear mRNA export protein SAC3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTSFGSVVPSTNFNFFKGHGNNDNTSANSTVNNSNFFLNSNETKPSKNVFMVHSTSQKKSQQPLQNLSHSPSYTENKPDKKKK----------YMINDAKTIQLVGPLISSPDNLGFQKRSHKARELPRFLINQEPQLEKRAFVQD-PWDKANQEK----MISLEESIDDLNELYETLKKMRNTERSIMEEKGLVDKADSAK--DLYDAIVFQGTCLDMCPTFERSRRNVEYTVYSYEKNQ--PNDKKASRTKALKVFARPAAAAAPPLPSDVR-----PPHILVKTLDYIVDNLLT----TLPESEGFLWDRMRSIRQDFTYQNYSGP----EAVDCNERIVRIHLLILHIMVKS-NVEFSLQQELEQLHKSLITLSEIYDDVRS-------SGGTCPNEAEFRAYALLSKIRDPQ------------YDENIQRLPKHIFQDKLVQMALCFRRVISNSAYTERGFVKTEN-----CLNFYARFFQLMQSPSLPLLMGFFLQMHLTDIRFYALRALSHTLNKKHKPIPFIYLENMLLFNNRQEIIEFCNYYSIEIINGDAADLKTLQHYSHKLSETQP----LKKTYLTCLERRLQKTTYKGLINGGEDNLASSVYVKD-----------PKKDRIPSIADQSFLMENFQNNYNEKLNQNSSVKPQINTSPKRVATRPNHFPFS--QESKQLPQISQSHTLSTNPLLTPQVHGDLSEQKQQQIK---TVTDGGSPFVFDQSAQNSTVEASKAHMISTTSNGAYDEKLSSEQEEMRKKEEQRIEEEKTQLKKKQENADKQVITEQIANDLVKEVVNSSVISIVKREFSEANYRK------DFIDTMTRELYDAFLHERLYLIYMDSRAELK--RNSTLKKKFFEKWQASYSQAKKNRILEEKKREEIKLVSHQLGVPGFKKSTCLFRTPYKGNVNSSFMLSSSDKNLIFSPVNDEFNKFATHLTKISKLWRPLEMQSIYYDNLTKKFPSNSLTPANLFIYAKDWTSLSNRWILSKFN---LQTAQDSKKFSNNIISSRIICIDDEYEPSDFSDLQLLIFNTGVTNPDIFDLEMKLK---------------------------DDGEELIKLITGISLNTNICFSLLIIYWES------------AENTLSESTIKHLLKLNRISKNYSSVIERIDLMNLTE----------------ESPHKCLEDKLSEISHSYVYKLTERGKYDKTLRQKRSLAGIHSRSTQLQTTKDIDQKMKKMLEKE--------------------------KNKYQQQIGERNTYAHLESHIDASPRSKKRKLPILLSTSHSSQFKTPLASR---------------------------------------------------------------------------LNTSGSSTSPPLPSHLAMKFRKNSR----------------------------------------VTSLHTVLPVSTPSHSNNIPAASFSGNNTTDIQSQQLIEN-------------------------------------------------QKSTSVYLNNVSERILGNQEICQTPINPVTPVLDGADQGKEDIPDSILELKILIDSVKKKVNND-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .: : .. . : . . . . : .:: . : * : . . . : : . :: : : : : . . ** :: . * : .: :* . . . :: *: : . : . .:: . *.: : * : .: * : : : : : :.: .: . .* .: : : . .:. : . : .: . :. :.: . : * . : . : . :: : . . * . * . . . . : . . : . : . . : . : . * *. : : : . .: : . . :: : . * : * :: .: . . : .. : . . .: . : * .: . . : : :: : . . ** :: . . . :. : :: . . . : . .: : : : :. : : : . . . . .: ::: : .. : . * . . : : . . . . : .:: . ", "identical_positions": 21, "similar_positions": 215, "identity": "0.96%" }, { "cls_id": "homologset.agr.MGI:1930121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ99-1", "uniprot_id": "D3ZQ99_RAT", "id": "D3ZQ99-1", "name": "PR domain zinc finger protein 15", "aln": "MPRHRPPASG--AAQFPERIATRSPDPTPLCTFHRQVSAMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSKDIPAGTELRVWYAAFYAKKMDKPMLKQACSSVQAAGTPEPSVTVEPERAQWVCKVCSNTFLELQLLNEHLLGHLEQSKSLPAGGQQQEAASEKEPDAPRMEPPTAVESKSMQSATVTKEPKKKPRRGRKPKASKVEQPLVIIKDKEP--AEHVAEIITEVPPDEPVNATPDERIMELVLGKLATPTSEASSVPKFLHHPSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEQVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDES---ADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKAAKRSHKRKQKPEEEAGAAVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTAPSSSVGLTNITVTPITTAAGTQFTNLQPVAVGHLTNPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQ--PEATNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAV------------PQTDVLQPP----QAPAAPQQ--AVQPQVQNEQQQ-------MYSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8T2-1", "uniprot_id": "PRD15_MOUSE", "id": "E9Q8T2-1", "name": "PR domain zinc finger protein 15", "aln": "---MCPPTIWEKGGQVGARWSLRAP----------EVSAMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSKDIPAGTELRVWYAAFYAKKMDKPMLKQACSSVQAAGTPEPSVSVEPERGQWVCKVCSNTFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDAPRMEPPTAAESKSIQSVMVTKEPKKKPRRGRKPKASKVEQPLVIIKDKEP--SEHVAEIITEIPPDEPVSATPDERIMELVLGKLAAPTNEASSVPKFPHHPSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNE-VDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDES---ADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTAPSSSVGLTNITVTPITTAAGTQFTNLQPVAVGHLTNPDRQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQ--PEATNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAV------------PQTDVLQPP----QAPAAPQQ--AVQPQVQNEQQQ-------MYSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57071-7", "uniprot_id": "PRD15_HUMAN", "id": "P57071-7", "name": "PR domain zinc finger protein 15", "aln": "---------------------------------------MAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPPNLEIRRLEDGAEGVFAITQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPAAEAEHQNLTAYQHGSDVYFTTSRDIPPGTELRVWYAAFYAKKMDKPMLKQAGSGVHAAGTPENSAPVESEPSQWACKVCSATFLELQLLNEHLLGHLEQAKSLPPGSQSEAAAPEKEQDTPRGEPPAVPESE----NVATKEQKKKPRRGRKPKVSKAEQPLVIVEDKEP--TEQVAEIITEVPPDEPVSATPDERIMELVLGKLATTTTDTSSVPKFTHHQNNTITLKRSLILSSRHGIRRKLIKQLGEHKRVYQCNICSKIFQNSSNLSRHVRSH-----GDKLFKCEECAKLFSRKESLKQHVSYKHSRNE-VDGEYRYRCGTCEKTFRIESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLEGVRRVKREDLEAGGENLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDES---ADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRRFAQKVNMLKHCKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPELTLEQEDLAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDATFSEYSEKETEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTAAATQFTNLQPVAVGHLTTPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQ--PEASNPQSVAHFINLTTLVNSITPLGSQLSDQHPLTWRAV------------PQTDVLPPS----QPQAPPQQ--AAQPQVQAEQQQQ-----QMYSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AX18-1", "uniprot_id": "A0A8M3AX18_DANRE", "id": "A0A8M3AX18-1", "name": "", "aln": "---------------------------------------MAEQTPD--EFIWCEDCGQYHDSECPELGPVVTVRDSFVLSRARSSLPDSLEIRLAEEGKEGVFVLRRLVRRTRFGPFEATRTSSLQTEGAFPLKIFQKDGSVVCFDTSNEDDCNWMMLVRPATDHKHQNLTAYQQDDDVYFNTSQDVLPGTELRVWYGAFYAKKMDRPVLRPPLLPPQPE-LPSNKPGDSP---------MKAPPPENLPVPDQLLCQTPAPAEDPPVPQVTEALSQN--NTAIIAP-------------IQPEPAKKQSRPRRTKTQKSVPSGAANSAQEAPVAESNEQPLSTVAPDVPLSVLDVQEVMVSVD-----------------PLPLKTSRLTRSPISSGKPILRKRTLRPGGDHKRVYQCCLCNKVFQNSSNLNRHIRSH-----GDKCFKCDECDKMFSRKESLKQHISYKHSKNE-PDIEYRYKCSTCEKSFRVENALRFHNCRTDDKTFQCEICSRFFSTNSNLSKHKKKHGEKLYACEICNKMFYRKDVMQDHQRRHVVGPKNLKREELEVNGEEGSKYRKEPSACPICGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDEQEREDFIKKIGISMEESDDSSDEEDEKNDPEHHKYSCKKCQVTFAKGRDYLKHIMEMHKEKGYNCTMCNRRFALKATYNAHLVIHRDHLPDPAVQKYIHPCEMCGRIFNSIGNLDRHKIIHTGVKSHCCEQCGKSFARKDMLKEHLRVHDNVRDFLCAECGKGMKTKHALRHHMKLHKGIKEYECKECNRKFAQKVNMLKHYKRHTGTKDFMCELCGKTFSERNTMETHKLIHTVGKTFSCSVCDKKYVTQYMLQKHTQLTHEKVEAQSCHLCGTKVSTRASMNRHMRRKHPEIVAVRLSEFD-ISEPSTVDASTISIAQPPLTLDKSSLTEKVSRNSKKRAKLLPHEPE------LSDSDEYSDFTSKNTEFPAAVGDETNSAVQSIQQVVVLTDPSAPPVSSSSVNLTNITVTPITTPAPAQFSNLQPVAVSHLTPSDRPLTLDSSILTVTFDTVSGSAMLHNRPPDLQSEAVGTVGATAPQSVAHFINLTTFVN---PLPHQL-EQPALTWRPVAADGAHTASIDDPQTDTAAPQGPSDQPQTLPEQRHQIQTQVTGPAQQQTTAAPQMFSY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: .: *******.************** *:************* .**** ::* ****.: :**:**:*****: *.:. :.*.*****:***** ******************** : ********:..****.**:*: .********.********:*:*: . :. *. . .. . . * : ::** : . . *. * * .:: ::. * * ** * *:.*..* . . . :*. :* : :: :.** *:.. :.:* * .* *.*. : *.: :*:: :: *:***::** *.*:*******.**:*** *** ***:** *:**********:*****:** * ****:*.:* *:**:*.**.**************:* *****************:* :***:*.********* ******: * :.:***:**..**. :*:****.**:*****************************************************:::**:** ***** **.**.***. *.* ******:**:**.:*::*******:*****:.*::*:*********:**:****::**** *********:***********:***:********.*****************:*****:*::*********************************:*:********** ***** ***************************** ::**********:******.****:*******:************.*********::***:.::* :.*.:*:***:*.*.** * *::..*:* :: **:: ::** :.:. :*::..*:.**..:***************** . . ...****.***********.* :**:*******.*** .:* * **.******************* *:* .. *: ************:** ** ** :* .****.* ****. * *. : *:* *.** ** *:**", "identical_positions": 705, "similar_positions": 229, "identity": "57.79%" }, { "cls_id": "homologset.agr.MGI:1930124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14630-1", "uniprot_id": "APOM_RAT", "id": "P14630-1", "name": "Apolipoprotein M", "aln": "-MFHQVWAALLYLYGLLFNSMNQCPEHSQLMTLGMDDKETPEPHLGLWYFIAGAAPTMEELATFDQVDNIVFNMAAGSAPRQLQLRATIRTKNGVCVPRKWTYHLTEGKGNTELRTEGRPDMKTDLFSISCPGGIMLKETGQGYQR-FLLYNRSPHPPEECVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1R3-1", "uniprot_id": "APOM_MOUSE", "id": "Q9Z1R3-1", "name": "Apolipoprotein M", "aln": "-MFHQVWAALLSLYGLLFNSMNQCPEHSQLTALGMDDTETPEPHLGLWYFIAGAASTTEELATFDPVDNIVFNMAAGSAPRQLQLRATIRTKSGVCVPRKWTYRLTEGKGNMELRTEGRPDMKTDLFSSSCPGGIMLKETGQGYQR-FLLYNRSPHPPEKCVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95445-1", "uniprot_id": "APOM_HUMAN", "id": "O95445-1", "name": "Apolipoprotein M", "aln": "-MFHQIWAALLYFYGIILNSIYQCPEHSQLTTLGVDGKEFPEVHLGQWYFIAGAAPTKEELATFDPVDNIVFNMAAGSAPMQLHLRATIRMKDGLCVPRKWIYHLTEG--STDLRTEGRPDMKTELFSSSCPGGIMLNETGQGYQR-FLLYNRSPHPPEKCVEEFKSLTSCLDSKAFLLTPRNQEACELSNN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NXE0-1", "uniprot_id": "A0A8M1NXE0_DANRE", "id": "A0A8M1NXE0-1", "name": "", "aln": "MIAATLWGLVSSVMGLFYVGLQVMVPCLPPAPLSTSVINT-DEYTGTWYFVAAAVWDEDDLKTLQTTDSIVLQIQKNSD-STLKVTETMRIGDACLKNVTNYYALPATSPFLFREDFDTIAVIWDGKYINCPTCIIMLYVGEDEEMNTFLFSRDEKTTEEAIQEFKSKTECLLMEDMWRAPLKNGYCKVDDSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*. : . *:: .: .*. . : : : * ***:*.*. ::* *:: .*.**::: .* *:: *:* .. . * *. . . : : .** *:: .*:. : :*:.*. :..*:.::**:* *.** : : :* :: * :... ", "identical_positions": 35, "similar_positions": 68, "identity": "18.13%" }, { "cls_id": "homologset.agr.MGI:1930125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LB91-1", "uniprot_id": "A0ABK0LB91_RAT", "id": "A0ABK0LB91-1", "name": "Programmed cell death 1 ligand 2", "aln": "-------------------------------------------------------MVRLIQTMLLLLLILNLSSQLHHIAALFTVTAPKEVYTVDFGSSVSLECDFDRRE----------------CTELEGIRASLQKVENDTSSQSQRATLLEELLPLGKASFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYVRIDTGILEVPGTGEVQLICQARGYPLAEVSWQN-----VSVPANTSHIRTPEGLYQVTSVLRLKPQPNRNFSCMFWNAHMKELTSAIIDPLSWMEPKVPRTRSLHAFIPACTVALIFLATVIAQRKR--------------LWGKLYSRKRSEPAVLGVGKIQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUL5-1", "uniprot_id": "PD1L2_MOUSE", "id": "Q9WUL5-1", "name": "Programmed cell death 1 ligand 2", "aln": "--------------------------------------------------------------MLLLLPILNLSLQLHPVAALFTVTAPKEVYTVDVGSSVSLECDFDRRE----------------CTELEGIRASLQKVENDTSLQSERATLLEEQLPLGKALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYMRIDTRILEVPGTGEVQLTCQARGYPLAEVSWQN-----VSVPANTSHIRTPEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRMEPKVPRTWPLHVFIPACTIALIFLAIVIIQRKR--------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ51-1", "uniprot_id": "PD1L2_HUMAN", "id": "Q9BQ51-1", "name": "Programmed cell death 1 ligand 2", "aln": "--------------------------------------------------------------MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGS----------------HVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPN-----VSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATVIALRKQ--------------LCQKLYSSKDTTKRPVTTTKREVNSAI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TBY4-1", "uniprot_id": "A0AB32TBY4_DANRE", "id": "A0AB32TBY4-1", "name": "", "aln": "MQIVLVGVNQEVIQCLFIVVHDIRRSADLRAEKLIAAQLSGRHGGFVCVYRLVCCVCMQGSMKRTLVIIFQALLWPAVLSASFTVNVPRSTYEAELNGDVRLECVFSALKRSSDITVIWSRVHPKPDVNIYWLDKGKEIHNHTSSAFHKRAQLISHLLRENRAVLHLKKLRIKDSGTYQCIVE-GDEVDYKQITLNVTAPFSPVR-KSLRKAGEDEVELSCESQGFPSAQVYWSDGQKLNLTLFSNTSVSSTDEDLILIVSKLKVERELVNNYTCTFIVKGEIQQT-ATFSIPEEIPLHGSALFVWIGAVIVVLLAVIFISIILHRRKYGQKNRRNEASKCAYLFPQSSSVNTDSLLTVNENRTHAREKSSTEKTASLRDSLTQQYSQLYTESEMKRKLRSYELHSRDGHCVNISSVIPEKGQILLLLGDSGCGKTTFTQILSYSWASRSQTDPFNTRRLRLLLLLHCSQNKGNLNQIINSSVQHERPVDVKQSLKGPEDCLLILDDYQEGNKDLEEFLKDHQTCRVLITSRPGVCPNLEKTVRTVLHLIHKPEESST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ::. ::* ***..*:. * : ...* *** *. . .:: : . : :: :* :** *:.. * .:* :*: .::::*.* *:*:: * *** :*::*.*.: : *. . .**:* *:: *:* *:* * : ::: :*** * *.* :.* *::: .*::* * : * * :. . : : : :*.**:: :: ** : ", "identical_positions": 58, "similar_positions": 85, "identity": "10.39%" }, { "cls_id": "homologset.agr.MGI:1930128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FCG9-1", "uniprot_id": "F7FCG9_RAT", "id": "F7FCG9-1", "name": "", "aln": "----MDFENLFSKPPNPALGKKPAADPEE----RIDETDGTEVEEAQTENVKRKVKRDCEPIPKKFKHLGHAGTPPKSLPRKKSR-----SKDYDPYSDGETCSQESEDNFDKELQQYIQAKEMASVAPPSLLPEESVKKAGTGDTQQTAKQKNKKSKAGLKKVKQKKMKRKWL------------------------------------------------------GTGNKGSNALLKIGG------------SQGKADGPEEKQPRVRMSQGFINQHT-----VERKGKQVCKYFLERKCIK-----------GDQCKFDHDAEIE-KKKEMCKYYVQGYCTKGENCLYLHNEYPCKFYHTGTKCYQGDHCNFSH-APLTAETQELLAKVLDTDKKSCK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ48-1", "uniprot_id": "ZC3H8_MOUSE", "id": "Q9JJ48-1", "name": "Zinc finger CCCH domain-containing protein 8", "aln": "----MDFENLFSKPPNPALGKKPAADPEE----RIDEIDGTEVEETQTEKVKWKVKRDREQIPKKFKHLGNAATSPKSLLRKKSR-----SKDYDPYSDGETCSQGSEDNFDKELQQYIQAKEMANAAQPSLLPEESVKKAGAEGTQQTAKQKNKKSKAGHKKVKQKKMKRKWP------------------------------------------------------GTGDKGSRALLKNSG------------SREQTDEPEEKQPRVRMSQGFINQHT-----VERKGKQVCKYFLERKCIK-----------GDQCKFDHDAEIE-KKKEMCKYYVQGYCTKGENCLYLHSEYPCKFYHTGTKCYQGDHCNFSH-APLTAETQELLAKVLDTDKKSCK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5P1-1", "uniprot_id": "ZC3H8_HUMAN", "id": "Q8N5P1-1", "name": "Zinc finger CCCH domain-containing protein 8", "aln": "----MDFENLFSKPPNPALG-KTATDSDE----RIDDEIDTEVEETQEE----KIKLECEQIPKKFRHS---AISPKSSLHRKSR-----SKDYDVYSDNDICSQESEDNFAKELQQYIQAREMANAAQ----PEESTKKEGVKDTPQAAKQKNKNLKAGHKNGKQKKMKRKWP------------------------------------------------------GPGNKGSNALLRNSG------------SQEEDGKPKEKQQ--HLSQAFINQHT-----VERKGKQICKYFLERKCIK-----------GDQCKFDHDAEIE-KKKEMCKFYVQGYCTRGENCLYLHNEYPCKFYHTGTKCYQGEYCKFSH-APLTPETQELLAKVLDTEKKSCK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22293-1", "uniprot_id": "SUS_DROME", "id": "P22293-1", "name": "Protein suppressor of sable", "aln": "MSVALADEPLIDLEEDLEDGEIDDDEEDEQQSSKIQVQKKTFVGDDDVQFVGVEAKNQNDDEDVVYVGPSTDAVCLQNSNSTKSKKPRPLEDDHASSIELAIANALKKKGIEPPMPRMRSSNQDTSDQSLEGSGEGLATANPLLQSTRSSRRRKRKKEREREQKKDKEQQNRSRRDENDVSVVPGGVEDMDEYEMMNVRGGSPPPGGAAPPLSSCGQRFSGADWDMDDGSAATGAAGLGAGGGGGYNSHSSYDSYSDEETNGPGLMNQRRRTRRDNEKEHQRGVNNRKRRDRDRLEGGLAGSGSKRNRRDSGEGGGGGQEKMGGSNRVEPRKLELCKFYLMDCCAKRDKCSYMHKEFPCKYYYLGMDCYAGDDCLFYHGEPLSEQLRNVLLKHMETAPKEILGDFKRISRDIAIVQMTRRHEQLCDQLNRENTWNSIGCGLMGKRQDHQMQQQQQQLQHQQLQQQQEQQQTQQQAAADGGGCIPSLLDMVINPPLSENKRKSRWTEKMGAKAAAGAAGSSERDSTSPDAKPLPPHLDLANLSHVLSAENMAKLNKLGITNLEQMLQVPFGQLTEAGLTLVEIGEIQRKAEDAKPQTQAELESSTPPSKRETEANNSNSKSNGLIMVDYTQYLKDAHVSFSGNDPLDDDRDDDEQLIIDDGNDSTAEEDQQPKKAKAPPAATHESSTEEAPLPSVFDLPSFMNNMLGQGSSARQLLPASATSPNQENAHLPGGDQSTHKSAPIGGGTSTNVLGRILFGDKQSDPEARAAFYRDIIRNPFKAHSGDGDVDSSNENSNSNSHSLTPTPTPEPGSQSPKPEDHDQDMPELPVIAPALPPTTPSLYVRRSMYDFDPVKEQEHGRQELLTEEKEQYQRDTDMRLPFEPMKHYMPATEIDAAIFSHTPIRWQLHEVTIEESSYAQIRASALHKEQRELRDPRMRRILGLPETPDNSGPLGSVPIMGPSSFSVDNIARCATTIASPDLETAVRDSTPSSPPPSVVNLPSMSVPPPSMRVPPPNIQVEKPTVRTDPRRDPRRAVLQAPTKGASTANTTAPNASGGSKQISEIRSLLQVSNWYNNLGTNNKIMVNQQLALVFTELKKFHQLPNDAPKIFDVSFIVNNTTLQQIFAKLFIFVDDNGEVVQIPEEPNGNGAALGGGGDSGGGVGGGGGGGGVVLPNLSQPPPNLSQMLRLPPPNIRMLRMSGMMMQMGNVGPPFNQPPPRGGLMGMPPNGNGLNQGVGNLGGLGQLGINQGGGPVPNGNPFNPFGGNNGGGAGVMNNMNSMGNMGMGFNNFNNNGGRGGHFPGGGSGGNGNGNNRNQRGGNHRNRNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *:. : * : :* :*: * * : : : : * : : : . :. **: ..*: : .. .:..: : : .:.: :. * .. : ::::::::: : :: *:*: :.: *.. .*: .* .* * : . * : : : ::* :*:.:: : * . * *.* *:. . .:* :* *:**:*: . *:: ::* *:*.*:***:*: * .** *: * * * **: : :::* * ::* *. ", "identical_positions": 55, "similar_positions": 108, "identity": "4.15%" }, { "cls_id": "homologset.agr.MGI:1930134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQY0-1", "uniprot_id": "ERN1_MOUSE", "id": "Q9EQY0-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "-------MPARWLLLLLALLLPPPGPGSFGRTSTVTLP---------------------------------------------------------------------------------ETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVE--EPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTG--EKQQTLSSAFADS-------LCPSTSLLYLGRTEYTITMYD--TKTRELR-WNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQGEVLRKVVHINVAVETLRYLTFMSGEVG-RITKWKYPFPKET-EAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINIVGQTSDNT--PTTVSQDVEEKLARAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSVHQQRQLQHQQFQKELEKIQLLQQQQ--LPFHPHGDLTQDPEFLDSSGPFSESSGTSSPSPSPRASNHSLHPSSSASRAGTSPSLEQDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF----AHLG--LEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPN--------AHGRIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSEDC----------------------------KDNPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACNLDCFHSDKHED----VIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKEALDGPIVRQLERGGR---AVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPHLLSHTYQAMELCR-HERLFQTYYWH-------------------------------EPTEPQPPVIPYAL--------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K2H4-1", "uniprot_id": "A0A0G2K2H4_RAT", "id": "A0A0G2K2H4-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "-------MPARWLLLLLALLLLPPGPGSFGRASTVTLP---------------------------------------------------------------------------------EALLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVE--EPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTG--EKQQTLSSAFADS-------LCPSTSLLYLGRTEYTITMYD--TKTRELR-WNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAVETLRYLTFMSGEVG-RITKWKYPFPKET-EAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENT--PTTVSQDVEEKLPRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQFQKELEKIQLLQQQQ--LPFHPHGDLTQDPDFLDSSGLFSESSGTSSPSPSPRASNHSLNSSSSASKAGTSPSLEPDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF----AHLG--LEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPN--------AHGRIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSEDC----------------------------KENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACSLDCFHSDKHED----VIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVRQLERGGR---AVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKRHHYRELPLEVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCR-HERLFQTYYWH-------------------------------EPTEAQPPGIPDAL--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75460-1", "uniprot_id": "ERN1_HUMAN", "id": "O75460-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "-------MPARRLLLLLTLLLP--GLGIFGSTSTVTLP---------------------------------------------------------------------------------ETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVE--EPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTG--EKQQTLSSAFADS-------LCPSTSLLYLGRTEYTITMYD--TKTRELR-WNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVG-RITKWKYPFPKET-EAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENA--PTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPSTSPRASNHSLCSGSSASKAGSSPSLEQDDGDEETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF----AHLG--LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPN--------AHGKIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSEDC----------------------------KENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHED----VIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGR---AVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCS-HERLFQPYYFH-------------------------------EPPEPQPPVTPDAL--------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQI8-1", "uniprot_id": "A0A8M1QQI8_DANRE", "id": "A0A8M1QQI8-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "----MMRMMKNWTQMLLLLVCFAGIVSQCEGGSSVSLP---------------------------------------------------------------------------------ESLLFVSTLDGSLHAVSKQTGDIKWTLKEDP-----IIQVPEYFQ--EPGFLPDPNDGSLYVLGGKRKEGLMKLPFTIQELVQSSPCRSS-------------DGVLYTGKKQDTWFVVDPQTG--EKQTSLSTSSSDS-------ICPSAPLLYIGRTEYMITMYD--TKTQELR-WNATYNDY-SAPLYDDKKYEYKMSHFASSGDGLVVTVDRDSGEVLWMQKFDSPVAGFYLWSQDSLRRAPHLTVATETLRYLTFTAENTQSHTMKWTYQFTKESHSTKTQLVPTLYVGKTESHLYASASLVHQGVAIVPKGLTLARIEGPMTAGVTMGNGRPECEITPSTDVKYPPGSSSS-----LQNQWLLIGHHEIPPLAHTTMLRDFPENLQRSGDVIPPRGS-------------GSSYRS--PSHPLPPVR-KQSSSPVLP----DSLSSEPMTVLVVTLLLGAWITFLLTHKWPVKKS-----QRSEEPVDSTPLSGLTN----YSASTELNTPP----STSSYSNSS--RSEKTSSVASNQTQPFSSKDSAPVTAASQSQN---EQADVVEVGKISFSPAEVLGHGTEGTFVFRGHFDGRRVAVKRILPECVEFAEREVQLLRESDEHPNVIRYFCTERDRQFTYIAIELCAATLQQYVEDPSC----PHSE--LNPVSLLEQTMCGLSHLHSLNIVHRDLKPRNILLSLPG--------ALGRVRALISDFGLCKKLPDGRHSFSLRSGIP-GTEGWIAPELLINAP----------------------------KGNPTSAVDIFSAGCVFYYVTSKGQHPFGDTLRRQANILSGVYNLDHFMEDIHED----VIGRDLIERMISAEPESRPSAASILKHPFFWSPEKQLQFFQDVSDRIEKEPTESPIVARLENSGR---SVVRTNWRMHISAPLQADLRKFRTYKGNSVRDLLRAMRNKKHHYHELPPEVQSALGEVPDGFVAYFTSRFPRLLLHTHTALSICA-PERPFHPYYHH-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JR46-1", "uniprot_id": "A8JR46_DROME", "id": "A8JR46-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MRFCVVVCCVLFLLASGLIASATAKSQQGDSAEVVSSGEDEKTDC----------------------------------------------------------------TDLARDEEALMVFSTLGGGLTAIDPVTSEIRWTIADDPPI---VAEHQENVQ--VPHFLPDPRDGSIYQLG--QMGSLKKLPYTIPQLVANAPCRSS-------------DGILYSGKKSDTWYMVDPKTGRREKVMGFGDATVDGKEGEQ-IGWATSRAIYLGRTQYTVMMYDSLAKNKDAKPWNITFYDYNAVSAPPELAKEYEYIHLTTTTNGQIVTLDRKHGKFLWQRDLSSPVVAAFLLGPDGLLSVPFTTVSDEAYQAILEESKTGN---------------VNTVKLFQSLYVGEHQKGLYALPSLVDKNTPRISTAPPIKLLDGPTGDQNSNQE-TDPRTIYINDVLQEHAG--------------IMLGHYNMPNEGNGNLQLSPTTASSKVVQSLATIHNYNDGYG-----LLANNEKN--AADIGVQTDPELVEIGIDQRTNGNTINRTKTIILQNSNKVQAFINEWFMEHPS---------GKVHQILIVIVLGMIALFWYTCSTMRELQKQS-----------ENGSKTFAIAQNGSNGSTGSNGSNANAEDLVDLGNG-------QVRVGKISFSTNEVLGKGCEGTFVFKGTFEERFVAVKRLLPECFTFADREVALLRESDAHENVVRYFCTEQDRQFRYIAVELCAATLQDYTEGDRS----LELQNHIDVWQVLSQAASGLSHLHSLDIVHRDIKPQNVLISLPD--------AKGKVRVMISDFGLCKKLNFGKTSFSRRSGVT-GTDGWIAPEMMRSQ-------------------------------RTTTAVDIFSLGCVYYYVLSGGHHAFGDNLKRQANILSHEYNLAKLRPEDDSEDSRIILAEQLISDMIHKDPQSRPPARCIGNHPLFWDEPKMLSFLQDVSDRVEKLQFHAEPLKSLEKNGR---IVVLDDWNVHLDPMITDDLRKYRGYMGASVRDLLRALRNKKHHYHELTPAAQKMLGCIPHEFTNYWVDRFPQLISHAYHAFSICS-NEPIFKPYYSAGYLFTRPWYFDADDALFPMLMLDPKPLPKIGSPKKTPSPASSQAQQLKQRKGLYNFRKPNDELPIPGVGLQRNLELDGQSLEPDGKRDVFANFKFRRYSKPGNNRNYNGGHKEAQDKEKYVIWTLPPSTQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32361-1", "uniprot_id": "IRE1_YEAST", "id": "P32361-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVASTKKLNFNYGVDKNINSPIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAANSISVPYLENRSLNELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEPSRLETYETLIIEPFGDGNIYYFN--AHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVEDEKVYTGSMRTIMYTINMLNG--EIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVIGKT-IFELGIHSYDGASYNVTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKS--LLASDLDFRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPFN-------PGDHESISSNKVYLDQTSNLSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKN--AIMGVHQIYNNEYDHLYENYEKTNSLDTTHKYPPLMIDSSVDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIHEQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQRFKILPPLYVLLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPFDMKSGK---QVVFEGAVNDGSLKSEKDNDDADEDDEKSLDLTTEKKKRKRGSRGGKKGRKSRIANIPN-------FEQSLKNLVVSEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRS--LIAEATDLISQMIDHDPLKRPTAMKVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIGVYMIVKENLSDDQILREFLYS-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : . ::. : : *.* *:. .. * *:: : : .: . :: **.:* :. .* *** :* :** :* : . * :* *. : :: .* * :. . :. .. : : . : : : . : :: : : . : : . . :* :: . . * . :. : . . . . . * : :. .*:*.. . :.. : : : . : : . . . :: : . : . : : .. : : .: . . . * . . .:** * .**.*::* *: * *****:* : :* *: ** *** * **:**:*:* :* ***:*** .**: .* . : :* * .*::*****.*:***:**:*:*:* .. . .:: :********** *: ** . . . **.** ***:: . . * ::**** ***:**: * * *.**.. *::**: .* : . . . :**. ** :* .**.* : .**:** * *.*: .****:* . :: .. : :* :: : :*.::* * . .: *****:*** **: :*. . :* :*. * *:..***.*: .: .. : :: : ", "identical_positions": 165, "similar_positions": 230, "identity": "12.95%" }, { "cls_id": "homologset.agr.MGI:1930136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVQ0-1", "uniprot_id": "PMFBP_MOUSE", "id": "Q9WVQ0-1", "name": "Polyamine-modulated factor 1-binding protein 1", "aln": "MLKLKGELRTAKGLKNEAGERDRDVSNLNSKLLSLQLDIKNLHDVCKRQGKTLQENQLCVEEAMLKANHNKKQAQTLVFTDNQMDFRVNKQYHLRQLQQLKKKLLTLQQELEFRTQELQASYCSLLQYQSILEKQTSDLLVLHRHCKLKEDEVILYEEEMGNHSKSTGEKLHLAQEQLALAGDKILSLERSLNLYRDKYQTSLSNIELLECQVKMLEGELSGLIGQDPENKGDHPKVRIYTSPCVIQEHQETLKRLSEVWQKVSEQDDLIQELRNKLACSNSLVLEREEALIKLQAEFASYTATHRHPPTSSEDCEDITKILKHLQEQKDSQCLHVEEYQNLVKDLRMELEAVSEQKKKIMKDMMKLELDLHGLREETSCVIEKKDKETVFLQYRLQDLQQQYTESQKLSLKKDKLLQDKDERLHELEKNLMQVQNSLREKEAELEKLQCTTKELDTSLQEARQSTSK-IDCEALRAEIQKLKDSLEEAREQLKVSDQNLTQSKEEAHLSASSLEDAHRKIENCLLQDKQKEEVIKDLQSQLHKLQKESSKIEEERKHNRQRLQELSSELSEGQRRLSNAEKEKSLLQKTLDEDEKKIDELFHSTQVSEQKQRELTNSIRKLEEELLEIKGLLEEKREQLKKSKEQEKALEEEIEALRQEAKRKEKMAKEHLRKLDEEKENLQAELTSRSSHLDSSLNKYNSSQKVIQELNAEIARQKDSIMILQTQLDSAIQKEKNCFQNMVSKEAYEELVRKSGNCQDDLTQALEKLTQATSETKSLNRSLQQTQERKAQLEDEIAAYEERMKKLNMELKKLQGFQQQSEQEVHNFDKKLEEMSNQVLQWQRQHQSDLKMLAAKESQLREFQEEMATLRESLLADEKEPYSPPAKLTPKETCRHHRENDQIMNNVEQWAKEQKIANEKLGNKLREQVKYIAKLTGEKDHLHNVMVHLQQENKKLKNEIEEKKLKAGNPRICVKAFPPNKLEPSQKGKLCCALGWRGIPQDLTPKTDH-KYMGLPHSSGSSYC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z221-1", "uniprot_id": "PMFBP_RAT", "id": "Q9Z221-1", "name": "Polyamine-modulated factor 1-binding protein 1", "aln": "MLKLKGEFRTAKGLKDE----------------------------------------------------NKKQAQTLVFTDNQVEFKSNKQYHLRQLQQLKKKLLTLQQELEIRTQELQASYRSLLQYQSILEKQTSDLLVLHHHCKLKEDEVILYEEEMGSHSKNTGEKLHLAQEQLALAGDKIVSLERSLNLYRDKYQTSLSNIELLECQVKMLEEELSGLICQDPENKGDHSKVRIYTSPCMIQEHQETLKRLSEVWQKVSEQDDLIQELRNKLACSNSLVLEREEALIKLRADFASYTATHRHPPTSSEDCEDITKILKYLQEQKDSQCLHVEEYQNLVKDLRLELEAVSEQKKKIMKDMMKLELDLHGLREETSCVIEKKDKETVFLQYRLQDLQQQYTESQKLSLKKDKLLQDKDERLNELEKKLTQVQCLFLEKETELEKLQSTTKELDANLQEVRQSTSK-IDNEGLRSEIQKLKESLEEAREQLRVSDQNLSQCKDEAHLSANNLEDAHRKLENCLLQDKRKDDVIKDLQSQLQKLQKESSETEEERKNNRQQLLELSSELNEGQRRLSSAEKEKSLLQKTLDEEEKKIDELLHGAKVSEQKQRELTNSLSKLQDELAETKRLLEEKREQLRKSKDQEKALEEEIEALRQESKKKEKMAKEQLRKLEEEKENLQAELSSCSSQLDSSINKYNNSQKVIQELNTEIARQKDSIMILQTQLDSAIQKEKNCFQNMVSKETYEELLRKSGTCQDDLTQALEKLTQATSETKSLQRNLQQTQERKAQLEDEIMAYEERMKKLNMELKKLQGFQQQSELEVHNFDKKLEEMGNQVLQWQRQHQSDLKMLAAKETQLREFQEEMTALKENLLADEKEPSLMPSKPAPKENYRHHRENDQIMCNVEQWAKEQKLANEKLGNKLREQVKYIAKLTGEKDHLHNVMAHLQQENKKLKNEIEEKKLKAGTPRICAKVLGPCKLEPSQKGKLCGALGWRGVCQDPLPKMDLTKYTGVPHCSGSSYC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBY8-2", "uniprot_id": "PMFBP_HUMAN", "id": "Q8TBY8-2", "name": "Polyamine-modulated factor 1-binding protein 1", "aln": "MKDEAGERDREVSSLNS-------------KLLSLQLDIKNLHDVCKRQRKTLQDNQLCMEEAMN-SSHDKKQAQALAFEESEVEFGSSKQCHLRQLQQLKKKLLVLQQELEFHTEELQTSYYSLRQYQSILEKQTSDLVLLHHHCKLKEDEVILYEEEMGNHNENTGEKLHLAQEQLALAGDKIASLERSLNLYRDKYQSSLSNIELLECQVKMLQGELGGIMGQEPENKGDHSKVRIYTSPCMIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIK---CKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLHSVMVHLQQENKKLKKEIEEKKMKAENTRLCTKALGPSRTESTQREKVCGTLGWKGLPQDMGQRMDLTKYIGMPHCPGSSYC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ** . :. :*****:*.* :.:::* .** *************.******::*:***:** ** *************::**:*****************.*.:.******************* **************:***************: **.*:: *:*******.*********:******* ***********:****************:******:*****:*:*** *****:**:***:****.****:***********************:*********::********************. **:***: .:** ***:** ::**:***:*****:**:*** *:****:* *** : :** **** *. :.**: .::*.:*..** : :.*::*:****:*****::* ::: *: :*.*:** *:. ***::**::: ** **:* :.*::** :*: ****** *:*:. **::: *** **.*. *:*..::*** ****: *:: *:::::. : ..::* .:. **:::* * . ***:*****:***::** :* *:****** *:*:* **: ***:**:***:*** . *::*:**:****.**:***:** *** **:*:* **:***.*:****: :*. ::**:*: * ***. ************.:.*******::.* ****:*****:** ********** **:**:**:*:** *** ********. ******:***.********* *********::*:*.** *:*** * .**:. * :* ***** *:*****:**:*******:***********:*******.**.**********:******:** ..*:*.*.: * : *.:*: *:* :***:*: ** : * ** *:**..*****", "identical_positions": 634, "similar_positions": 221, "identity": "61.91%" }, { "cls_id": "homologset.agr.MGI:1930140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFW6-1", "uniprot_id": "WDR6_RAT", "id": "Q5XFW6-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "---------MDAFGDYVWPRATSELILLPVTGLECVG-DRLLAGEGPDLLVYNLDFGGHLRMVKRVQNLLGHYLIHGFRVQPEPKG------------DLDSEAMIAVFGSKGLRVVKISWGQSHLRELWRSGLWNMSDWIWDARWLEGN--------VALALGHNSVVLYDPVIGC-----MLQDVPCTDRCTLSSACLIGDTWKELTIVAGAVSNELLVWYPATALP-----DNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQN----IGHCFGHSARVWQVKLLEN----YLISAGEDCVCLVWSHEG--------EILQAFRGHQGRGIRAIAAHER-----QTWVITGGDDSGIRLWHLVG-----RGYPGLGVSSLSFKSPSRPGALKAVT--LAGSWRVLAVTDVGGLYLYDLEVKCWEQLLED-NRFQSYCLLEAAPGPEGFG-----LCALANGEGLVKVVPINTPTAAVDQNLFQGKVHSLSWALRGY---EELLLLASGPGGVVACLEISAAPTGKAIFVKERCR--YLLPPSKQRWHTCSAFLPPGD-FLVCGDRRGSVLLFPARPCLFKKPGVGPKAITAAEAPQAGSSSGGSESVVTGLGPVSSLHSLHGKQGVTSVTCHGGYVYSTGRDGSYYQLFVHGGRLQPVLRQKACRGMNWIAGLRMAP-------------------------DGSMVVLGFHANEFVVWSPRSHEKLHIVNCGGGHRSWAFS-----------DTEAAMAFAYLKDGDVMLYRALG--GCIRPNVILREGLHGREITCVKRVGTVTLGPEFEVPNLEHPDSLEPGSEGPGLIDIVITGSEDTTVCVLALPTTTGAAHALTAVCNHISSVRALAVWGVGTPGGPQDSH----PGLTAQVVSAGGRAEMHCFSLMITPDASTPSRLACHIMHLSSHRLDEYWDRQRNRHRMIKVDP-ETRYMSLAICELDSDRPGLGPGPLVAAACSDGAVRLFLLQDSGRILHLLAETFHHKRCVLKVHSFTHEAPNQRRRLILCSAATDGSIAFWDLTT----AMDRGSTTLEPPAHPGLPYQMGTPCLTVQAHSCGVNSLHTLP------TPEGHHLVASGSEDGSLHVFTLAVKMPELEEADGEAELVPQLCVLDEYSVPCAHAAHVTGIKILSPKLMVSASIDQRLTFWRLGNGEPTFMNSTVYHVPDVADMDCWPVN--PEFGHRCALAGQGLEVYNWYD----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME2-1", "uniprot_id": "WDR6_MOUSE", "id": "Q99ME2-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "---------MDAFGDYVWPRATSELILLPVTGLECVG-DRLLAGEGPDLLVYNLDLGGHLRMVKRVQNLLGHFLIHGFRVRPEPKG------------DLDSEAMIAVFGSKGLKVVKVSWGQSHLRELWRSGLWNMSDWIWDVRWIEGN--------VAVALGHNSVVLYDPVIGC-----MLQDVPCTDRCTLSSACLVGDTWKELTIVAGAVSNELLIWYPATALT-----DNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRLWKVGDLRVPGGRVQN----IGHCFGHSARVWQVKLLEN----YLISAGEDCVCLVWSHEG--------EILQAFRGHRGRGIRAIATHER-----QAWVVTGGDDSGIRLWHLAG-----RGYPGLGVSSLSFKSPSRPGALKAVT--LAGSWRVLAVTDVGSLYLYDLEVKSWEQLLED-NRFRSYCLLEAAPGPEGFG-----LCALANGEGLVKVVPINTPTAAVEQKLFQGKVHSLSWALRGY---EELLLLASGPGGVIACLEISAAPTGKAIFVKERCR--YLLPPSKQRWHTCSAFLPPGD-FLVCGDRRGSVMLFPVRPCLFKKPGAGSKAITAAEAPGAGSGSGGSESVPTGIGPVSTLHSLHGKQGVTSVTCHGGYLYSTGRDSSYFQLFVHGGHLQPVLRQKACRGMNWVAGLRMVP-------------------------DGSMVILGFHANEFVVWSPRSHEKLHIVNCGGGHRSWAFS-----------DTEAAMAFTYLKDGEVMLYRALG--GCIRPNVILREGLHGREITCVKRVGTVTLGPEFEVPNLEHPDSLEPGSEGPGLIDIVITGSEDTTVCVLALPTTTGSAHALTSVCNHISSVRALAVWAVGTPGGPQDTR----PGLTAQVVSAGGRAEIHCFSVMVTPDASTPSRLACHVMHLSSHRLDEYWDRQRNKHKMIKVDP-ETRYMSLAICELDNDRPGLGPGPLVAAACSDGAVRLFLLQDSGRILHLLAESFHHKRCVLKVHSFTHEAPNQRRRLILCSAATDGSLAFWDLTT----AMDKGSTTLELPAHPGLPYQMGTPSMTVQAHSCGVNSLHTLP------TPEGHHLVASGSEDGSLHVFTLAVKMPEPEEADGEAELVPQLCVLEEYSVPCAHAAHVTGVKILSPKLMVSASIDQRLTFWRLGQGEPTFMNSTVYHVPDVADMDCWPVS--PEFGHRCALAGQGLEVYNWYD----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NNW5-1", "uniprot_id": "WDR6_HUMAN", "id": "Q9NNW5-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "---------MDALEDYVWPRATSELILLPVTGLECVG-DRLLAGEGPDVLVYSLDFGGHLRMIKRVQNLLGHYLIHGFRVRPEPNG------------DLDLEAMVAVFGSKGLRVVKISWGQGHFWELWRSGLWNMSDWIWDARWLEGN--------IALALGHNSVVLYDPVVGC-----ILQEVPCTDRCTLSSACLIGDAWKELTIVAGAVSNQLLVWYPATALA-----DNKPVAPDRRISGHVGIIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQN----IGHCFGHSARVWQVKLLEN----YLISAGEDCVCLVWSHEG--------EILQAFRGHQGRGIRAIAAHER-----QAWVITGGDDSGIRLWHLVG-----RGYRGLGVSALCFKSRSRPGTLKAVT--LAGSWRLLAVTDTGALYLYDVEVKCWEQLLED-KHFQSYCLLEAAPGPEGFG-----LCAMANGEGRVKVVPINTPTAAVDQTLFPGKVHSLSWALRGY---EELLLLASGPGGVVACLEISAAPSGKAIFVKERCR--YLLPPSKQRWHTCSAFLPPGD-FLVCGDRRGSVLLFPSRPGLLKDPGVGGKARAGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGKQGVTSVTCHGGYVYTTGRDGAYYQLFVRDGQLQPVLRQKSCRGMNWLAGLRIVP-------------------------DGSMVILGFHANEFVVWNPRSHEKLHIVNCGGGHRSWAFS-----------DTEAAMAFAYLKDGDVMLYRALG--GCTRPHVILREGLHGREITCVKRVGTITLGPEYGVPSFMQPDDLEPGSEGPDLTDIVITCSEDTTVCVLALPTTTGSAHALTAVCNHISSVRAVAVWGIGTPGGPQDPQ----PGLTAHVVSAGGRAEMHCFSIMVTPDPSTPSRLACHVMHLSSHRLDEYWDRQRNRHRMVKVDP-ETRYMSLAVCELD--QPGLG--PLVAAACSDGAVRLFLLQDSGRILQLLAETFHHKRCVLKVHSFTHEAPNQRRRLLLCSAATDGSLAFWDLTT----MLDHDSTVLEPPVDPGLPYRLGTPSLTLQAHSCGINSLHTLP------TREGHHLVASGSEDGSLHVFVLAVEMLQLEEAVGEAGLVPQLRVLEEYSVPCAHAAHVTGLKILSPSIMVSASIDQRLTFWRLGHGEPTFMNSTVFHVPDVADMDCWPVS--PEFGHRCALGGQGLEVYNWYD----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEZ5-1", "uniprot_id": "A0A8M2BEZ5_DANRE", "id": "A0A8M2BEZ5-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "MKSTACCADCEMASPVESAVVKSAVLVAPITALEFLGEDFLLTGEGPILSVYSLQAS---PKKCASINVLQNYRIHGIRPYKKHQSGGIPFSGASSASDNSYKGDIIVFGGKGVRLVSFESEGQCLKLIG--PLLELQDWVLDIHCFKRQP----HSLLGISLAHNAIMLLEAESGN-----IISFYSCVETCLLYSALMVGPNWDSVVLVGGTVFNQLVLWRPAGTKL-----SGQ-SQVERRLLGHSGVIFSLCYLQESGWLASASDDRSVRLWSVGTLGGDAGCGKESPTCLRVLYGHQARVFCVKLTPS----RLFSAGEDGACLLWEWGGEG------KVGCAFRGHKSGGVRALAVSEGSISCRAGWVATGGADGGVRLWRVAEGKKISEETQEETQLDLGFRGHGCPKVVRLVG--EGESNAILVCTDQGEVCLS--QGDIWDVIWQGGSEFQSYCVMEVASIQVQNSDCIVQVCAVGNLNGGVQVFLVGQPGVGVFLRAGEGKVHSVLWVKGLFGESGNVCLLASGSEGLVYRWTINVTEDKSGLHIKEEALLPFLLPPCAKRWLTAAVTLSQRNGFCLCGDRRGSLLLYMER----ENNDRINEGEESRIDSQDQETENRQTELVSSLSPISTLYGVHGKQGVTSVCEYQDLCYSTGRDGSVRILTVEESTLKVRRVHRACKGMDWLEMVLFLGSDGPERMLNKTIVKRTNDTGRESIAEARFVMVGFHSVHFVIWDPHRQEKLLSVTCGGGHRSWAFKRPISTHIDTQTQALRQGTLVFIKQGAVMASRSLMSTDTSVNGHTLKEGLHGRGISCVCHLGSLSG-------------------DLSELWEVFVTGGEDTTVGVLAVCPQSGIVKVLAVLTDHISIVRALAAIRRGDMNERERNNGMETSVLSSLVFSAGGRAQLQCYRLLIHLD-EQQSQPICQVTQIAGHRLDEQWERKRNRHKTVKMDP-ETRYMSIAVVQNE------SEGVLLALGCSDGAVRLFSVNESSRSVDVLWECFYHQRCVLSVATCKLEDSQGRKLLLLFSATTDGCISVWDLTA----VLNSKASVSWQGPS--------VPFFSIPVHQSGVNTLALSPRTEKGQTEDNVISLASGGDDGQLSLLRIKIDQAEQE------NGVASLQLLSHWSIPLAHSSPLTGLCLLSPALLASTSPDQRMCLWSVESDGLRPLQVRFSHIADAAGLWAWRSEG-QEGGAWIVVCGQGLQLFQLTEKEIDEAENGRAEGEERKKVMFSHQCSRT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08924-1", "uniprot_id": "WDR6_YEAST", "id": "Q08924-1", "name": "tRNA (34-2'-O)-methyltransferase regulator RTT10", "aln": "--------------------MKDLSHYGPALCVKFYN-DYVLAGYGPFIHVYDYHSATLINKCR----LFHYNKVHGLSLSS--------------------EGKILAYGARSVTIVELEDVLKKESLVDFERIN--SDWITGATFSFDN------LQIYLLTCYNKVLICDLNCEV-----LFRKSLGGERSILYSGIIKVFGPDKVYVNAGTVMGGVIIWDLFSETK-----IHN-------LLGHEGSIFYVNLSNNGRYVASCSDDRSIRLWDLETGKQ-----------LSVGWSHTARIWNLMFFDNDS--KLISVSEDCTCRVWNIIESRENVAELSISNVYEVHLIKSIWGVDVKDD-----EMIAVTSGNDGRLKLIDLLQLKRHGDEETSFSLDDIAKQCGDIFEKNESIKGFQWFSFGVIAITSLGKILKYSDVTKQWKLLLTN-EKFNSYPITNGIQTQNIAV------FSNNKSDILLIKFSKDSADIIETEEFHLDELSKTNNCLVTEYDDDSFLLTLQSPNPREKFVCLEISLQNLKIKSKHCFN--------KPENFSSSCLTSFRN-HILVGSRFSTLVIYNLLD----------ESEEPFIIRRLSPGDTTTSIEFVEDKDNSAVFSVTNRDGYYVFIELTKNSLEEGPYRLSYKVLHSNKMMK-----------GFLEGAFFNS-------------------------KGEYITYGFKSSLFYLYNETNCYELASEVCGGSHRLWNLA-----------KITDGHVLMYIKASRFHLRKIYN----SIVPETLENGVHGREIRDISICPVSNTNTN----------------DNFKDGHIFCTASEDTTIKLGYFNNRTGKVQNFWTQRKHVSGLQRCQFIN------------------HKLMISSSAREELFLW------------------------ELNDKYNKRPYMTIRQALPV-STNNSDLRIMDFDVKFISQSGDFLLVTVYSDSTIKIWHYRENQNKFDLIMQGRYKTCCLFNVVFIALK-----EELLVVISPTDGHLVVYNITEYVPFSVDPISGDLVDHKLDATISNLPAPVAQLPVHQSGVKSLDYVAN-----ATRTSATILTGGDDNGLGLSNLKLDD-----------SNKVTLKTSDFIAAAASSTITSGMLINGGKEVITTSVDQVIRAWEITAGKLSLVDKKRTTVADTGSLEIISNDEDADSEKTLLIGGVGLSIWKK------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q86B53-1", "uniprot_id": "WDR6_DROME", "id": "Q86B53-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "-----------------------MVLISDAFGLEISP-NGILVGHGDQAVLYSSEPKVELPVQLR------EGKVRGFAWSSLRKS----------------QRLLLLYSENEYSLIRCTTSSEN-DLFQLVYEGETRDWINAALFLEDENESEDRKRFVLHTSHSALLYMEYDLTSNADCTVLELARCTDSSILYYTKLHGSSFNKLAIISGNAFGELLVWQTQFPTESDPKSVMKTYPLLLRIEAHNGVIHSIEFDLQSQLLVTTSDDRSVKFWNIQKSGDWTTAEIKP---MFSCYGHSSRVMCVVILKIDDRTFVASGGEDSYVCIWSSSG--------ELILKRRQQFGAPIWRLGFSQD-----AEILYSTSSTGNLVGQNLKEVLN--RPKIESTILSSLGDANEFVRNLKFVN--NEIIVGLSSLNRLYYTRISPDSSHENKWLMVN--DFPSYKRTVLEVFDDIIAT-----CGHRRITLHRYNTNTNDFEQLFDGIRMKGTIRSFQFLSRDR---------YLVSDNLGYCLLLQTHQLHIESHIALFNN--------REPWITAALLISEQY--LLLGNREGHVMLYCRSS----------ASDDFQLKDSIRYLHGKMGSNFFKLLSLNADNAHVMSGGHEAFLKYLSVRFSDSTLRVSQREGIP---------------LAWVEASPSDD-----------------------------LILGFNDNHIVAWS-RRNDILLQLACGGGHRCWDFRLS---------DGDSQLSIAYVKQKRVYFYRNSLY--NAVDNRLKDIEPNNWHVRNCNTLRLITP--------------------RNQSDPFILSAGDDNIIKVTQVTNDS--LSQRAEMHSHISTVRSLQAIPYKSNGGDSS---------TWLVFSVGGRSQLCISQLSIDAS-------------------NKCWISEISSHTLHNVAASKTSTIEARLMAIDVVQHSDGDLFSIYVAGGDGNISHYIWELETPNQLDLKHFVDIQRCPLGIQWIASKG-------MLLVSTTNGEVYGFDRTL-------------------------ETTYFQLQLHVTGINTIDIYVD-------RHLLHILSGGDDESIKYTVLNLNNN---------NVEQKIEYLGLHNAQVNALAIHCPTKSVAASELFAYTCSIDRQIYRIDLSTHKYKRVGYTCIADVKGMLLDEHQR-------MYFYGCGLQTMSISNIL--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :*.* * :*. . ::*: : : :. . :: . **: : . : :. :: : :: : . * : ..: : .* . . :::* : : .* * *. : . :.: *:***:::*.: : :.* :*: : : : * .** :*. .: . : : : : : . . : : . : : . . . : . * ** . . . . : . . :. :.: . : *.* . :::: . .: . * . . :: : **: : :. * ***.** * : . : ::* . : :. : . .. : .:*. : : . : .*:* :: :.* ..* :: :. : . : .* . : : . : .*. : : . . : . * : : : :: :.*:* : :: * .. : * *:::: : :*.:* : : :. : . : : : . : : . :.*. .: . . * **. . ", "identical_positions": 59, "similar_positions": 217, "identity": "4.58%" }, { "cls_id": "homologset.agr.MGI:1930146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM54-1", "uniprot_id": "APR_MOUSE", "id": "Q9JM54-1", "name": "Phorbol-12-myristate-13-acetate-induced protein 1", "aln": "MPGRKARRNAPVNPTRAELPPEFAAQLRKIGDKVYCTWSAPDITVVLAQMPGK-SQKSRMR-SPSPTRVPADLKDECA-QLRRIGDKVNLRQKLLNLISKLFNLVT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U777-1", "uniprot_id": "APR_RAT", "id": "Q5U777-1", "name": "Phorbol-12-myristate-13-acetate-induced protein 1", "aln": "MPGRKARRNAPLNPTRAELPPEFAAQLRKIGDKVYCTWSAPDITAVLAQMPGKKSRKSTMRRSPSPTRVPADLKDECD-QLRRIGDKVNLRQKLLNFISKLFNLIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13794-1", "uniprot_id": "APR_HUMAN", "id": "Q13794-1", "name": "Phorbol-12-myristate-13-acetate-induced protein 1", "aln": "MPGKKARKNA----------------------------------------------------QPSPARAPAELEVECATQLRRFGDKLNFRQKLLNLISKLFCSGT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***:** .***:*.**:*: ** ****:***:*:******:***** *", "identical_positions": 37, "similar_positions": 11, "identity": "34.91%" }, { "cls_id": "homologset.agr.MGI:1930150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HBU9-1", "uniprot_id": "POPD2_HUMAN", "id": "Q9HBU9-1", "name": "Popeye domain-containing protein 2", "aln": "-MSANSSRVGQLLLQGSACIRWKQDVEGAVYHLANCLLLLGFMGGSGVYGCFYLFGFLSAGYLCCVLWGWFSACGLDIVLWSFLLAVVCLLQLAHLVYRLREDTLP-EEFDLLYKTLCLPLQVPLQTYKEIVHCCEEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLQPSEEGVFQVTLTAETSCSYISWPRKSLHLLLTKERYISCLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLGPT--AADAGPESEKGDEEVCEPAVSPPQATPTSLQQTPPCSTPPATTNFPAPPTRARLS---RPDSGILASRIPLQSYSQVISRGQAPLAPTHTPEL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ES82-1", "uniprot_id": "POPD2_MOUSE", "id": "Q9ES82-1", "name": "Popeye domain-containing protein 2", "aln": "-MSANGSSVAQLLWQPPVCRSWKPDVEGAVYHLANCFLLMGFMAGSGVYGCFYLFGILGPGYLCCVLWGWFDACGLDIVLWNVLLTVACLLQLAQLVYRVRVNTLP-EEFNLLYRTLCLPLQVPLQVYKEIVHCCHEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLHPSEEGTFQVTLTAETECSYISWPRKNLYLLLNRERYISRLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLSPS--ASDGEPESEKDDEEALEAAVSPAQARPICIVPTPPCSAPPATTNFPVPLPRARMPRMPRPDSGNLASRRPLQNSSQVMSRSQAPLAPIHTPEL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6JWV8-1", "uniprot_id": "POPD2_DANRE", "id": "Q6JWV8-1", "name": "Popeye domain-containing 2", "aln": "MNSGDSSLIDAVIYNHTLCDGWTNSTEGAIYHLGNTILFLGYMGGSGAYGALYIFSFLAPAFLCLALWGWLTMCGLDVFIWNLLLMLQCLAQVCHLIFRLMRDGLANEEFSALYTAVYLPLDVPVQVFKEITGAGENKVLSLAAEETYAVEGKTPIDQLSFLLSGRIRVSLEGQFLHYIFPHQFLDSPEWESLRPAEEGNFQVTLTAETDCRYISWRRRRLYLLLSKDRYIARLFSVMLGSDIADKLYSLNDKLFAKSGVRLDIRLPSLYHVLAPSPPGSEGGSASSPPRGSLGDPTVIKVDPAPSNPGSGTRNPQPDQGKNPVPKNPHQHWSSDTEMPSGEDSTSLILEDFADMTG---SLMDYGHEREYLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:.* : :: : . * *. ..***:***.* :*::*:*.***.**.:*:*.:*...:** .****: ****:.:*..** : ** *:.:*::*: : *. ***. ** :: ***:**:*.:***. . .::**:**:*:******:***::**:*****:*** :*********:**:********:*:*** *********.* **** *: *:***.::***: ***.:** **::***:******** *:*:***********.*: .::. . *. . :.:* :. * . . * .* .: : . . ** :: *:. ::: . : : * * ", "identical_positions": 166, "similar_positions": 115, "identity": "44.5%" }, { "cls_id": "homologset.agr.MGI:1930153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJH9-1", "uniprot_id": "A0A096MJH9_RAT", "id": "A0A096MJH9-1", "name": "", "aln": "MEKNSSLWKSLVTEHPLCTTWKQEAEGAIFHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVHSITFAREFHVLYSSLFKPLGIPLPVFRTIALSSEVVTLEKEHCYAMQGKTSIDRLSVLVSGRIRVTVDGEFLHYISPFQFLDSPEWDSLRPTEEGIFQVTLTADTDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKKHHYDIRLPNYYQLSSPDLSRSPLTEQFRNSRQHCNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES81-1", "uniprot_id": "POPD3_MOUSE", "id": "Q9ES81-1", "name": "Popeye domain-containing protein 3", "aln": "MEKNSSLWKSLVTEHPLCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLSSAVWAWVDICAADIFSWNFVLFVICFMQFVHIAYQVHSITFARDFHVLYSSLFKPLGIPLPVFRTIALSSEVVSLEKEHCYAMQGKTSIDRLSVLISGRIRVTVDGEFLHYISPFQFLDSPEWDSLRPTEEGIFQVTLTADTDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKKHHYDIRLPNYYHMSTPDLSRSPLTEQFRNSRQHCNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBV1-1", "uniprot_id": "POPD3_HUMAN", "id": "Q9HBV1-1", "name": "Popeye domain-containing protein 3", "aln": "MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRTIALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:******.*: ***:************:********************************.********:***************************:******:*:*******:****.**************:****************:**:*:**************** *:*************************:**************************************************::********:*::*:*:: *****::*:***::*:*", "identical_positions": 256, "similar_positions": 32, "identity": "87.97%" }, { "cls_id": "homologset.agr.MGI:1930171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5C0-1", "uniprot_id": "D4A5C0_RAT", "id": "D4A5C0-1", "name": "Nectin-3", "aln": "MARTPGPALLCPGGGKAQLSSASPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCG-ALAGSIIVEPHVTAVWGKNVSLKCLIEVN--ETITQISWEKIHGKSTQTVAVHHPQYGFSVQGEYQGRILFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLMKGPDSLIDGG----NETVAAVCIAATGKPVARIDWEGDL--------GEMESTITSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIR---YSFILDIQYAPEVSVTGYDGNWFVGRKGVN-LKCNADANPPPFKSVWSRLDGEWPDGLLASDNTLHFVHPLTFNYSGVYVCKVTNSLGQRSDQKVIYISDPPTTTTLQPTVQ--WRSSTADVQDLATE--HKKLPFPLSTLATLKDDTIGTIIASVVGGALFVVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQHDEHDSYPD-----SVKKENKAPVNNLIRKDYLEE-PEKTQWNN---------------------------------VENLTRFERPMDYYEDLKMG---------------------------------MKFVSDERYNEN--------------------------------------EDDLVSHVDGSVISRREWYV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLB9-1", "uniprot_id": "NECT3_MOUSE", "id": "Q9JLB9-1", "name": "Nectin-3", "aln": "MARTPGPAPLCPGGGKAQLSSAFPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCG-ALAGSIIVEPHVTAVWGKNVSLKCLIEVN--ETITQISWEKIHGKSTQTVAVHHPQYGFSVQGDYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG----NETVAAVCVAATGKPVAQIDWEGDL--------GEMESSTTSFPNETATIVSQYKLFPTRFARGRRITCVVKHPALEKDIR---YSFILDIQYAPEVSVTGYDGNWFVGRKGVN-LKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTVNYSGVYVCKVSNSLGQRSDQKVIYISDPPTTTTLQPTVQ--WHSSPADVQDIATE--HKKLPFPLSTLATLKDDTIGTIIASVVGGALFLVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLHQDELDSYPD-----SVKKENKNPVNNLIRKDYLEE-PEKTQWNN---------------------------------VENLTRFERPMDYYEDLKMG---------------------------------MKFVSDERYNES--------------------------------------EDGLVSHVDGSVISRREWYV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQS3-1", "uniprot_id": "NECT3_HUMAN", "id": "Q9NQS3-1", "name": "Nectin-3", "aln": "MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCG-ALAGPIIVEPHVTAVWGKNVSLKCLIEVN--ETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG----NETVAAICIAATGKPVAHIDWEGDL--------GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIR---YSFILDIQYAPEVSVTGYDGNWFVGRKGVN-LKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQ--WHPSTADIEDLATE--PKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPD-----SVKKENKNPVNNLIRKDYLEE-PEKTQWNN---------------------------------VENLNRFERPMDYYEDLKMG---------------------------------MKFVSDEHYDEN--------------------------------------EDDLVSHVDGSVISRREWYV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EG3-1", "uniprot_id": "NECT3_DANRE", "id": "Q58EG3-1", "name": "Nectin-3-like protein", "aln": "----------------------MALTMTAHFLRNNPIQLGLNLRVLLMLSFVSGLVYGSQVIVPPKVNAVLGKNVTLSCRVQVDTNLSLTQSSWERKLPNGWVTLAVYNPMFGISIPPDYERRLSFRSPSALDATIMLEDVGFADIGVYTCKVATFPLGNTQASTTVSVLVEPKVYVSAGSSALIDGG----NETTVATCIAERARPPADVSWETNLY-------GMSEAHMQEDANGTTTTQVHYIWQPSRHAQGHTLTCVVKHPALQSDFR---IPYIINVQFAPDILVLGYDGDWYVGRENVQ-LKCRAKANPPAQHFRWIRLDGEMPNGAERVNNTLVFTRPLQKNDSGVYRCEVANDIGLHSRDIRIRIQDPPSTTTMPPTTP--VRLLTADISATAPG-NKQRALITSPTLAPLHEGSLGTIVGGAVGGALFLLLLLILAGVYYQRQRRTFRGDYYTKQYHGPSDMQKAP-----QPHELQQVYS--KGSPDTKLKSNQDNGTIYPD-----KDREEWGD---FDRERS------------PNG-----RSRALREAGQLNHHN--HQNHEHG------------FHSNHHTGH-----------PQSYSPAHHIQRSSLQPQPRRYPAPQVMS-----------NGSPYLPEDCYDNEYVSHTDGSMISRREWYV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HC72-1", "uniprot_id": "A0AC58HC72_DANRE", "id": "A0AC58HC72-1", "name": "Nectin cell adhesion molecule 3", "aln": "-----------------------MAEEVRHFFGNTTLFRRLLPLLGFLFSACDG-VWSNQVVVPAQVTSVLGKNVTLSCRMEMSSNLSLTQSSWERHLPSGIITLAVFNPVYGTSVADEYSRRVHFLKPSVHDVSIVLQGVGFADIGMYTCKMVTFELGNMQASTNVDVMVEPKVYVSPGSLSLTADD----GETLVATCTAERGRPAAEVFWESDLP-------GQTAVVTQSEPEGTTTTLVHYVLAPTRASHGRSLSCVVRHPALSRDFR---IPYRLNVFFVPDVMVIGGKNVWYVGQKDVQ-LDCKANANPPALFYLWTRLDALMPAGVNMHNGSLVFTRPLEATDSGQYRCEVQNDVGQNFHDVPFLVLDPPPTTAAPTTTTTFSKSLHPDTSLTITAPINQRAHFSSPTRSSPRDADLSTLVGGIVGGILILVLLLALAGAFYMRRRRTFRGDYYTKQYIGPSDMQKESQLDVLEPHELQDVYGDDSGNGSQDLKPKPEGDIIYPDYPNDHKDTEGWGDNLSLQREASYYSDHHNHHNVNPSGPPLHNGSPYLRDECFDNATDNDYVSHIDGSVISRREWLRSLFIRRHHSRMNHQLFQHIFCTADALPAATHYWKTSIHTHSHTYTLANLKYSIHLHSHVFRLWGKPRAPRRNLRKHVENMQTGPAGTRIMTFLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15278-1", "uniprot_id": "FAS3_DROME", "id": "P15278-1", "name": "Fasciclin-3", "aln": "--------------------------------------MSRIVFICLAAILTDALTWAQVNVEPNTALLNEGDRTELLCRYGRS-------INYCRIEIPGEQKVLNLSPEWSKTPGFTYFG----AGLTAGQCGVSIERVKASNNGQVKCSLG-VEGEELSGTIDLVVALRPQQPIIELLSRPNREGYFNEGTEFRARCSVRDGRPPANISWYIDNMPANKRTTPLEVMSSTNDNVELSTSVQEIQWHLSPEDSNRKLVCRSHHQTDRESVPPQEAAYIINVRYAPVHQPDAAVYGLYLEHTAIVNITIRASPQP---KIEWT-IDGAIVG---------------QGRTDGRYSAYEPQYLGNDEYNVTLAIAG----LTLEDTTK--IYNLRASNELGLTD---YQVRISSSSKPPSSSLDVAAIVG-IVVAVAVLVLVVLLIVFARATGRWCFGGKSIKTPTNETSDTESADIKATSTATATTTMGG----VGVSAEEEETVNEQESPQEQQQQQQKKAKRLPAFAAAILR----------------------RFNEKDSRKYKDNQESLNIVEG-------------------------------SVQEIPATNNAIDG--------------------------------------NDNEPKAIVWQSTSPVWTFK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : . *... * * . .: : . .: * :. : * : : : :. : :: * *. . : ..: : * :.* : . . * * . .:* * : * : . :* . : .: : * :* : .. .: ::: :.* . :: : : : .*..:* * :*. .* * . : :* : : : . : * .. . . : :. .: .. . :.:::. * . .::*: * * * *. . .** :. . : . : : .. . * . . . . : : ", "identical_positions": 35, "similar_positions": 125, "identity": "5.12%" }, { "cls_id": "homologset.agr.MGI:1930182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V816-1", "uniprot_id": "G3V816_RAT", "id": "G3V816-1", "name": "Nucleoside diphosphate kinase", "aln": "MICLVLTIFANLFPSAYSGVNERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELRERPFYSRLVKYMGSGPVVAMVWQGLDVVRASRALIGATDPGDAMPGTIRGDFCVEVGKNVIHGSDSVESAQREIALWFREDELLCWEDSAGHWLYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV85-1", "uniprot_id": "NDKC_MOUSE", "id": "Q9WV85-1", "name": "Nucleoside diphosphate kinase C", "aln": "MICLVLTIFANLFPSAYSGVNERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELREKPFYSRLVKYMSSGPVVAMVWQGLDVVHASRALIGATDPGDAMPGTIRGDFCMEVGKNVIHGSDSVESAHREIALWFREAELLCWEDSAGHWLYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13232-1", "uniprot_id": "NDKC_HUMAN", "id": "Q13232-1", "name": "Nucleoside diphosphate kinase C", "aln": "MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTF3-1", "uniprot_id": "NDKC_DANRE", "id": "Q9PTF3-1", "name": "Nucleoside diphosphate kinase C", "aln": "MIILCLTIFANIFKPGWTGANERTFLAVKPDGVQRRLVGEIIRRFERKGFKLVGMKLLQASEAQLRQHYWELREKPFYNGLVKYMSSGPIVAMVWQGLDVVKTARKMLGETNPADSLPGTIRGDYCVEVGRNVIHGSDSVESAAREISLWFEDHELFCYEECGQHWIYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36010-1", "uniprot_id": "NDK_YEAST", "id": "P36010-1", "name": "Nucleoside diphosphate kinase", "aln": "----------------MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ****:********* **.:*: ***:**:***.:**::*.: *.:** * :**: :*.:* ***::* **:* ***: .* ::* *:* .: *******: :::*:*: ******:** *** ***. **. :*. :*:* ", "identical_positions": 77, "similar_positions": 44, "identity": "45.56%" }, { "cls_id": "homologset.agr.MGI:1930187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES73-1", "uniprot_id": "MAGD1_RAT", "id": "Q9ES73-1", "name": "Melanoma-associated antigen D1", "aln": "MAQKPDGGAGLRGFQAEASVEDSALLVQTLMEAIQISEAPPTSQATAAASGPNASPQSSQPPTANEKADTEVSAAAARPKTGFKAQNTTTKGPN---DYSQARNAKEMPKNQPKVAFKSQNATSKGPHAASDFSHAASTGKSAAKKSEMAFKGQNTTTKAGPSATYNFTQSPSANEMTNNQPKT-AKAWNDTTKIPGADAQTQNVNQAKMA----DVGTSAGISETDGAAAQTSADGSQAQNVESRTIIRGKRTRKINNLNVEENSNGDQRRASLASGNWRSAPVPVTTQ-NPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPP-ARQSPPARQTPSAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPIVWPNPMAWQSTPGWQSPPSWQAPPSWQSPQDWQGPPDWQLPPDWSMPPDWSFPSDWPFPPDWIPADWPIPPDWQNLRPSPNLRSSPNSRASQNQGPPQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGIIFMNGNRATEAVLWEALRKMGLRPGVRHPLLG-DLRKLLTYEFVKQKYLDYRR--VPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARNRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQAFTGPIIGPSGTATANFAANFGAIGFFWVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYH6-1", "uniprot_id": "MAGD1_MOUSE", "id": "Q9QYH6-1", "name": "Melanoma-associated antigen D1", "aln": "MAQKPDGGAGLRGFQAEASVEDSALLVQTLMEAIQISEAPPTSQATAAASGPNASPQSSQPPTANEKADTEVSAAAARPKTGFKAQNATTKGPN---DYSQARNAKEMPKNQSKAAFKSQNGTPKGPHAASDFSQAAPTGKS-AKKSEMAFKGQNS-TKAGPGTTYNFPQSPSANEMTNNQPKT-AKAWNDTTKVPGADAQTQNVNQAKMA----DVGTSAGISEADGAAAQTSADGSQTQNVESRTIIRGKRTRKVNNLNVEENNSGDQRRASLASGNWRSAPVPVTTQQNPPGAPPNVVWQTPLAWQNPSGWQNQTARQTPPAARQSPPARQTPSAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPIVWPNPMAWQSTPGWQSPPSWQAPPSWQSPQDWQGPPDWQVPPDWSMPPDWSFPSDWPFPPDWIPADWPIPPDWQNLRPSPNLRSSSNSRASQNQGPPQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGIIFMNGNRATEAVLWEALRKMGLRPGVRHPLLG-DLRKLLTYEFVKQKYLDYRR--VPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARNRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQAFTGPIIGPSGTATANFAANFGAIGFFWVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5V3-1", "uniprot_id": "MAGD1_HUMAN", "id": "Q9Y5V3-1", "name": "Melanoma-associated antigen D1", "aln": "MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAAS-----PQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQ-NPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPP-ARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLG-DLRKLLTYEFVKQKYLDYRR--VPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTSRAARSQNAIPSQEAQQP--VDVVDAKVRAILNYILDHTAQKIPIKDKDLI--AVAGDKSELKKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVASIHELTPAQRPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFG-HHLSMAQEGVNAE-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. *.: ...* . . ** * ::: :.. :::*:: : *:*** .::: : .. : : . :* :.*** *. :* : :* : : *. : *:: ** :** **:.*** :: *: *. :.: *. .* :* :*** : ****:**. .* :. : .: **** *: * : ::::* ::: ::.*: : :.:. *:*.::* ", "identical_positions": 54, "similar_positions": 91, "identity": "6.85%" }, { "cls_id": "homologset.agr.MGI:1930188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P82930-1", "uniprot_id": "RT34_HUMAN", "id": "P82930-1", "name": "Small ribosomal subunit protein mS34", "aln": "---------------------------------MARKKVRPRLIAELARRVRALREQLNRPRDSQ--------------------------LYAVDYETLTRPFSGRRLPVRAWADVRRESRLLQLLGRLPLFGLGR------------------------LVTRKSWLWQHDEP----CYWRLTRVR-PDYTAQNLDHGKAWGILTFKGKTESEAREIEHVMY--HDWRLVPKHEEEAFTAFTPAPEDSLA----SVPYPPLLRAMIIAERQKNG--------DTSTEEPMLNVQRIR----------------------------------MEP-WDYPAKQEDKGRAKGTPV--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JIK9-1", "uniprot_id": "RT34_MOUSE", "id": "Q9JIK9-1", "name": "Small ribosomal subunit protein mS34", "aln": "---------------------------------MARKKVRPRLIAELARRVRALREQRNQPRDSQ--------------------------LYALDYETLTRPHSGRRLPVRAWADVRRESRLLQLLARLPLFGLGR------------------------LVTRKSWLWQHDEP----CYWRLTRVR-PDYTAQNLDHGRAWGILTFKGKSEDTAREIEQVMY--HDWRLVPKHEEEAFTAFTAKPEDRLN----SVPYPPLLRAMILAERQKNG--------DTSVQEPLLNLERTR----------------------------------MRP-WDYPAKQETKGRAKGTPV--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QEG6-1", "uniprot_id": "F1QEG6_DANRE", "id": "F1QEG6-1", "name": "", "aln": "---------------------------------MVKKK-RLRLIAEMARKIRAYRELKNRPRDSQ--------------------------RYALDYDTMTRPFSGKKLPVLAWKDVQRETRLFSLLSGMRMFGLGR------------------------LFTRKSWLDEHTEP----CYWKITKVK-VDYTAENMDHGKAWGVLTFRGKEEPKEREVDKVMY--HDWRLVPKHEEEEFRRCEPVPEPAAR----SVRYPPLLRAMILAQQAKEQG-----VEVSTLPEPLLPLKRVV----------------------------------TLN-QEYFRRQDELKKQEGTPV--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV39-1", "uniprot_id": "Q9VV39_DROME", "id": "Q9VV39-1", "name": "", "aln": "----------------------------------------------MAQKV-------------------------------------------IKYIGRTTDFRG--------------NTLWELVSNLPNWGVGR------------------------LLIRN-MFQRYPEP----CYMRILKVQSVDEQPGEIRKVRVTVEKTWRGVTQPKPVEIYSTSYK-ADYELVPQDQEAKYLNNKKKVEPVILPT--KIELPPLLRELVSEETGNPN-------PQMKVHYKLTDNKMAR----------------------------------LAKDGEKPTVNFALGVGQPKPVSAKLYEGLL-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LAI2-1", "uniprot_id": "A0ABK0LAI2_RAT", "id": "A0ABK0LAI2-1", "name": "SPRY domain-containing SOCS box protein 3", "aln": "MMTPRTRTYFRILIQWSCEIFLIALPKANRNFGSGLTGCASLLTAVLSRETRPRAKLSDSPPSAAGPMQRGGGDCLRRDRNGKWVSPGGARWLQVLFTMARRARSSRAWHFVLSAARRDTDARAVALAGNSNWGYDSDGQHSDSDSDPEYSSLPPSIPSAVPVTGESFCDCEGQNEATFCNSLHTAHRGKDCRCGEEDEGECLAVGTCAGLGRFSGLEGSTLLCPSLVWAFYPTDFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGDGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYHHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATRLQNRRFYPMVCSTAAKSSMKVIRSCASSTSLQYLCCYRLRQLRPDSGDTLEGLPLPPGLKQVLHNKLGWVLSMNCSHWTSPAPPPGTAAPAAERDSRETRPCQRKRCRRS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::. : : . :. :* . . : : * : * : . . * * . * : : * . : : .: . . : . : . . * ", "identical_positions": 8, "similar_positions": 33, "identity": "1.64%" }, { "cls_id": "homologset.agr.MGI:1930190", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96RY5-1", "uniprot_id": "CRML_HUMAN", "id": "Q96RY5-1", "name": "Protein cramped-like", "aln": "-----------------MTVKLGDGGSGEDGLKKLGKR--------AADEESLEG--EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSP--QDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG---KKVRRQWESWSTEDKNTFFEGLYEHGKDFEAIQNNIALKYKKK-GKPASMVKNKEQVRHFYYRTWHKITKYIDFDHVFSRGLKKSSQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKLCDPDGLSDEEDQKPVRLPLKVPIELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIEFLKQKWALHEVRVRKTLEERQLQDSCSAPMQEKVTLHLFPGENCTLTPLPGVARVVHSKAFCTVHWQEGGRCKQSAKDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTP----AEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPG------PGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWL---GPGRQDPRPG-------SLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNS-RHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLT-KAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGS-DPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGNSRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSIAEPGRREALFDGGGGGPAVSDLSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PG95-1", "uniprot_id": "CRML_MOUSE", "id": "Q6PG95-1", "name": "Protein cramped-like", "aln": "-----------------MTVKLGDAGSGEEGLKKLGKR--------TADEESLDG--EGPGGADAAD-SSSTKRDGQTPRA--SGAPAPPRGLPTPSPPQGSP--QDQHHFLRSSVRPQSKRPRKDAPCALGSGGASGSGPRGKGSDGGASSSGNVSGATPATPAGGSRSSSRNIGSSGPEKEEG---KKVRRQWESWSTEDKNTFFEGLYEHGKDFEAIQNNIALKYKKK-GKPASMVKNKEQVRHFYYRTWHKITKYIDFDNVFSRGLKKSSQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKLCDPDGLSDEEDQKPVRLPLKVPVELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIEFLKQKWALHEVRIRKTLEERQLQGSSTVQTQEKVALHLFPGENCTLTPLPGVARVVHSKAFCTVHWQEGGRCKQGTKDIHSLPPAQILGIQSGQGIARGQLKCQRSSAEGKGGGRLLPTADASQSSGESSPESAPAEGAAPSLSSPDAPDRPHG-LQDSGPHLEKTPVTALAVGRDSPIQESGALPCPCGQPPDLEDELSLLDPFPRYLKSCQDLIIPEQCRRADTRSGREHPPLGSVASPETLTPSSGAVADSAPPGLDPQPGTDHQPDTRLQSDICTKELANASSEESQEKGSPSEHLSSQGQPATRPSKEVPASQLAQQLREEGWSLQTSESLTLAEVYLMMGKPTKLQLEYDWLAVLGPESQAPTAQGQTALSRSSPSALHQQRLLSCLLRLISTEVHPKMAFEANTASTASVRPTQEEQSTTPPGKVVTINSRSPRCSRNPSTLRSNKTFPSASAPCSPGLRNPPRPLLVAGPSSTGSSDSDGGLFAVPTTLPPNS-RHGKLFSPSKEAELTFRQHLDSISIQSDFFSPKPKKLRKRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSPIAGRGWFRPIQSSLT-KAALSRPIVPKVLPSQATSHLPSAIDLAAQSAGIIPGSPLPILDTDGSSGISPLSSEQATTAISGQGDTGPHQNRDPVTAVRGTNDPFISVT-RPEQEPMTDGFQGSPALTLPELSKANLQNGLSIPLPSSESSSTRLSPPNVSALLDISLPGPPEDVLSQGEPATQISDSIIEIAISSGQYSEGVPLSPAKLNGSDSSKSLPSPSSSPQPNWIASPTHDPQWYPSDSADSSLSSLFASFISPEKSRKMLPTTVGANSGTSLLGPSLLDGNSRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSITEPGRREVLFDGGGGGNPVGDLSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RIJ0-1", "uniprot_id": "A0A8M1RIJ0_DANRE", "id": "A0A8M1RIJ0-1", "name": "Protein cramped-like", "aln": "MVKRKKTPSASEELENGMTVGQG-GGSGVEGPSKPDRKPEGGEDGESADQASEETSTKRVGEETLNPSSTASPGSAPTPSTQTSSPPGPQVNPTALSPGLAVPNNQDQHHFLRSSVRPPSKRIRKDASSPALNGHG---GAKAKGAEAGPSVCVAAAAGSAGGSGAGGTSRSAPKGQGPAEKEEGGSQKRVRRQWESWSTEDKNSFFEGLYEHGKDFEAIQNNIALKYKKK-GKPASMVKNKEQVRHFYYRTWHKISKHIDFNNVYSRVLKKSSQELYGLICYAELRKKVGGLMDDKNVAKLNELIQQGATTVRSKGRNLRIKAPMCRALKKICDPDGVSDEEDQKPVRLPLKVAVELQPRSNHSWARVQSLAHNPRLRMVIELHRKVSTLIEFLKQKWAVQDQRIRKSLAEREALDG-LAQSSESEELFLFPAESSTVTALPGVARVVHSKASCTVHWQESGRGRTGIRD---LPAAHILGIQPARG---------KSGKPGPVGG------DSKRTDGHPVEGSDSSSTSAAGLETSANPN----------------------VNTTSPVSPTITSLLPIGPEG-------------------------NPAGSAEQEPASQTQTDAGGGDKQIETVTQGDPASSE--GRTDEPG--------------------------TAGGVASEKALPQSEAQGRVEEVVGTGRSPQQIREEGWSSQVSENVTLAELYLMLGKPGKLQLEYEWQ-------SKPNPP---------SVLPNSQNVLRCLLRLVSSEVNPKPTPEVCSVGTSPLKSGQEESSVTPPGRTPAGANRSPSWGRQQHAARSKILLN------NPGGRNLPRSLLASG------GDSEG--FAVPTTLPPNSSRQSRMFSPNKEAELAFRQQLDSIS--SDIFSKQRKIGRGRPLRKPLVVQRTLLPRTAGDTSPHVCSFSILSNSSATGTGSFRPIQTRLAPNRQPSSKASSSTGSPAPVTQLSSAIDLAAKSAGIIPGSPCREVEAPSID-----------------------------KAIVESEDAMGSAPAAPEMEPDILD---------QEPSEESLQNGVSPPSPGGGES--LLAPPSVASLLDISLPGPPEESLPSGEPQTQISDSIIELAINS-HYGDGSLLSPPKLNGSDRSKLLPSSCDS----WMPSPTHDPQWYPNDSTDSSLGCLLSSLASPDKTR---RTALPPSSSTALLGPSLLDSNSHDCFQSRGLPDAAEV-DTQLACMMSESSVDYIARFNDLAQELSVTETTLP----------PPHGD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5BK20-1", "uniprot_id": "JUPI2_RAT", "id": "Q5BK20-1", "name": "Jupiter microtubule associated homolog 2", "aln": "-------------------------------------------------------------------MFRGADGQASKSGFRSMKPPGGESNDIFGSPEEGVP--SSKPHRMASNIFGPTEEPKNIPKRTN----------------------------PPGGKGSGIFDESTPVQTRQRLNPPG---------------GKTSDIFG---------SPVTATAPLAHPNK-PKDHVLLCE-------------------------------------GEDCKSDLKAATN------------------------------------------STPRGEQGEKGSSTEAEPAKIPEPIPTVDSHEPR----LGPRPRSHNKVLNPPGGKSSISFY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76906-1", "uniprot_id": "CRM_DROME", "id": "O76906-1", "name": "Protein cramped", "aln": "--------------------------------------------------------MEELSKQPPPPPLTQPPPPSSSVSIEEPLPNGKGGGAVVVNSIAKLP----EEELLGSVTMHNCPGTRASARVIQKMKQD-----------------QTRPMTPPPSEREPNKKEEKAAQKTPSQLKTG-------SGKTTWTNVERNCFFDALNEFGKDFEAVANCINAKLKRRNANSDYSFKTKDQVRQHYYQTHHKICKYVR----FSEELKKPAQELYTLINYGEMRRKLQ-FLTEKHFMKLKQLVYQGQITVRCKGKNIRIKTPSCKALRRLNQLDDSLED-----IRLPSKVEVLVTPANMEAFGRVQSLAQNPRGRIIVPLHKKLISFIKTFEYKWRSANQRLHEEKSAYFSSSLPSAASNNNN------NNNETEPLQPSVASLDPSMCFQPRPGVAIHRPLLSITAYLSSISICLTAYEERMG------FKVRSETLGNLAGMSVAANKRLRTESGSEKRSPETKKPKSSASPPLEKSLDDGPLEGN-----------LMKMENSSGDELGEEIHEFLGDILEAMQHPQAATIPALSATTGDTTNVAVALETSHDPVQQAYPANADLSNAMATSVLQTSCAAAPAPSTPVTG--------------------SLAAPSVARSKRKEAKEAAAAAQARNFKPLLSDDILKRIR-KGWTQANAADITIGDLYVVFGQDSKLELEYYWC------------------------------------EVDSSTAMASSILTINTVTPSSSSVGTQTGSAASNANQTGASSNCYVSASSNSSTSST---------------------------------------SLPYNPNDCDSVERVRAVTTSSVSNKLKHLLLVANLSERVRKRQCNCGHTCDRKRDLMTKAQQLAEATATGGVGGMVEGNFRTPMLPVRRPISNIDPVRQLSALTRQKISRQVLVQRRLLPPTSAGDRPYDLLSVRQLHSG-----------------------------------------------------------------------LFEPIDRVDGTSSAGISTSGSKPDCSMNAMTASQDQEPGDQGALEFLNDEATQVSARDMPNLDICVATNRTDVSSSLNEAAQDGSTTQSFFQGSMSP--MHLLRDSTSNARWLEDNINDFSLTSLLGHLDEIDATR-------------DILDP------------------------SSSMSVISESSVDFRHKFQEIAALLQQQEKD--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .. * : . : * : . .. . . * . . :* ..: .: : . .::: . : * *: : . . . *. .** : : : *. ", "identical_positions": 10, "similar_positions": 42, "identity": "0.75%" }, { "cls_id": "homologset.agr.MGI:1930197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD72-1", "uniprot_id": "D3ZD72_RAT", "id": "D3ZD72-1", "name": "", "aln": "------------------MAAQKKRLSVKEAFQLAQQPHQN-------------------QAKLVVALSRTYG-------AVNDKTAFQEEFVHYLKYAMVVHKREPAVERVMDFTAKFVTSFHQ----SDQEEEEEEKDGG-----ILNYLFTFLLKSHEANSSAVRFRACQLINKLLGNMPENAQIDDDLFDKINEAMLIRLKDKIPNVRIQAVLALSRLQDPK-----------DHDCPVVDAYVTLIENDSNPEVRRAVLSCIAPSAKTLPKIVERTKDIKDIVRKLAYQVLAEKVHMRALSIAQR---VLLLQQGLSDRSDAVKQAVQKHLLQGWLRFTEGNILELLHRLDVENSSD-------VAVSVLHSLFSMSP---LSELVGICKDDDGRKLIPVETLTPEIALYWCTLCEYLKSKGDEGEEFLEQILPEPAVYAEYLVSYIQGFPVVNEEQKSDFTYIGNLMTREFIGQQLILIIKSLDTSEEGGRKRLLAILQETLTLPTTPISLFSFIVERLLHIVTDDSKRIQIVTEIISEIRAPIVT---------VHVD--PSDTRKKELKMAEIKVKLIEAKEALENCIAVQDFDQASKLKEEIKTLEDARINLLKETEQ---LEIKE--VQTEKNDVETLQKCFILCYELLKRMSISTGIGATMNGIIESLILPGIISVHPIVRNLAVLCLGCCGLQDQNFASKHFILFLQVLQIDD-VTIKVSALKAIFDQLMMFGIEPFKAQKVKAVHCEGAE-------LSSPDEQEE-DAEDRATAKSVLKLLSDFLD-SEVSELRTGAAEGLAKLMFSGLLVS-SRILSRLILLWYNPVTEEDVRLRHCLGVFFPMFAYASRTNQECFE---EAFIPTIQTLANAPASSPLAEVDVTNVAELLVDLTRPSGLNPQAKNSQDYQALTVHDNLAIKICNEILTNPCSPE----NRVYTKALSLVELSSS----VTKDLLLLLDEILEQ-VTDRTCLRALEKIKIQLG--KGSKEF-DQCVVTEDANTTTKVLQDENE-----------------------------YRTPARNVKGTQASKSTQGKTNRGRRKAPVSSKTNRRCQTAGPDSE------------SDHEPP---SEMRMRLP---RRAKTAALQKSKLNLAEFLNEDPS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PWG6-1", "uniprot_id": "E9PWG6_MOUSE", "id": "E9PWG6-1", "name": "", "aln": "------------------MAAQKKRLSVKEAFQLAQQPHQN-------------------QAKLVVALSRTYG-------AMDDKTAFQEEFIHYLKYAMVVYKREPAVERVMDFTAKFVTSFHQ----SDEEEEEEENDGG-----ILNYLFTFLLQSHEANSSAVRFRVCQLTNKLLGNMPENAQIDDDLFDKINEAMLIRLKDKIPNVRIQAVLALSRLQDPK-----------DDDCPVVDAYVNVIENDSNPEVRRAVLSCIAPSAKTLSKIVGRTKDIKDTVRKLAYQVLAEKVHMRAMSIAQR---VLLLQQGLNDRSDAVKQAVQKHLLQGWLRFTEGNILEFLHRLDVENSSD-------VAVSVLHSLFSMTP---LSELVGICKNDDGRKLIPVETLTPEIALYWCTLCEYLRSKGDEGEEFLEQILPEPAVYAEYLLSYIQGFPVVNEEQKGDFTFIGDLMKREFIGQQLILIMKSLDTSEEGGRKRLLAILQETLILPTTPISLVSLIVERLLHIIRDDNERIQIVTEIISEIRAPIVN---------VVVD--PSDTRKKELKMAEIKVKLIEAKEALENCIAVQDFDQASKLKEEIKILEDAKINLLKETEQ---LEIKE--VHTEKNDAETLQKCLVLCYELLKQMSTSTGITATMNGIIESLILPGIISVHPIVRNLAVLCLGCCGLQNRDFASKHFMLFLQVLQIDD-VTIKISALKAIIDQLMMFGIEPFKTQKVKGVQCEGEE-------INCHDKQEENDAGETDPAKSVLKLLSDFLD-SEVSELRTGAAEGLAKLMFSGLLVS-SRILSRLILLWYNPVTEEDVRLRHCLGVFFPMFAYANRTNQECFE---EAFIPTVQTLANAPVSSPLAEVDVTNVVELLVDLTRPSRLNPKAKNSQDYQALTVHDNLAIKICNEILTSPCSPE----NRVYTKALSLVELSSN----VTKDLLLLLDEILEH-VTDRTCLRALEKIKSQLG--KGGKES-DPGVVTQDVNTTTAVLQNENE-----------------------------YMTPVRDGKGTQTSKSTQGKSKRGCRKAPVSSKTNRRRQIAGPDSE------------SDHEPP---SEMKMRLP---RRAKTAALQKSKLNLAEFLNEDTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BPX3-1", "uniprot_id": "CND3_HUMAN", "id": "Q9BPX3-1", "name": "Condensin complex subunit 3", "aln": "------------------MGAERRLLSIKEAFRLAQQPHQN-------------------QAKLVVALSRTYR-------TMDDKTVFHEEFIHYLKYVMVVYKREPAVERVIEFAAKFVTSFHQ----SDMEDDEEEEDGG-----LLNYLFTFLLKSHEANSNAVRFRVCLLINKLLGSMPENAQIDDDVFDKINKAMLIRLKDKIPNVRIQAVLALSRLQDPK-----------DDECPVVNAYATLIENDSNPEVRRAVLSCIAPSAKTLPKIVGRTKDVKEAVRKLAYQVLAEKVHMRAMSIAQR---VMLLQQGLNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRLDVENSSE-------VAVSVLNALFSITP---LSELVGLCKNNDGRKLIPVETLTPEIALYWCALCEYLKSKGDEGEEFLEQILPEPVVYADYLLSYIQSIPVVNEEHRGDFSYIGNLMTKEFIGQQLILIIKSLDTSEEGGRKKLLAVLQEILILPTIPISLVSFLVERLLHIIIDDNKRTQIVTEIISEIRAPIVT---------VGVNNDPADVRKKELKMAEIKVKLIEAKEALENCITLQDFNRASELKEEIKALEDARINLLKETEQ---LEIKE--VHIEKNDAETLQKCLILCYELLKQMSISTGLSATMNGIIESLILPGIISIHPVVRNLAVLCLGCCGLQNQDFARKHFVLLLQVLQIDD-VTIKISALKAIFDQLMTFGIEPFKTKKIKTLHCEGTE-------INSDDEQESKEVEETATAKNVLKLLSDFLD-SEVSELRTGAAEGLAKLMFSGLLVS-SRILSRLILLWYNPVTEEDVQLRHCLGVFFPVFAYASRTNQECFE---EAFLPTLQTLANAPASSPLAEIDITNVAELLVDLTRPSGLNPQAKTSQDYQALTVHDNLAMKICNEILTSPCSPE----IRVYTKALSSLELSSH----LAKDLLVLLNEILEQ-VKDRTCLRALEKIKIQLE--KGNKEFGDQAEAAQDATLTTTTFQNEDEKNKE------------------------VYMTPLRGVKATQASKSTQLKTNRGQRKVTVSARTNRRCQTAEADSE------------SDHEVPEPESEMKMRLP---RRAKTAALEKSKLNLAQFLNEDLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJY8-1", "uniprot_id": "F1QJY8_DANRE", "id": "F1QJY8-1", "name": "", "aln": "------------------MPGDAD-LQIEEAFRRAQKAHNN-------------------KAKLVASLKNGYN-------KLEDKTQFHEEFIRCLKYAMIIYTREPAVENVIDFVSKFAASFEIPVNEEAEEEEEEEEDNE-----FLNFLFNFLLESHGANSHAVRFRVCQLVNKLLGSLSENAQIDDDLCDRIHEAMLVRVTDKYPNVRIQAALAMARLQDPT-----------NSDCPTIKAYVLLLENDSNPEVRRAVLSCIAPSAVTLPKIYKRTRDVKEKVRKLAYEVLAEKVHIRALTIAQR---VSLLHEGLSDSSDSVKEVVRAHLLPAWLRLLQGDVLQLLHRLDVENCAD-------TAVTALHAIFSMATS--PDDLMQNGVRLDERKLIPVNSLTCENVLYWRALCEFVKSKGNEGEELLEQLLPEAAIYAEYLYSFLKSITQLSEAQRADMTQLEMVMTQEFVGQQLILLVGCLDTSEEGGRKRMVAVLQEILVMPNTPVSLIGLLVEKLVNILRDDAQKIQMVAEIISDVREPIFP---------ISEPVDENEKRRKQVRLAEVRVQIMEAKQTLEDCISCQDFSRAAELKDSISQLEELKNQLTLEVSQPA-ENVKE--QRIEKSDPETLLKCLTMCAELFKQMSIKRGVCPTMIALIESLILPSVSNPNPAVRNMAVICLGTAALHSKDLANTHLVLLLQITQLDE-PKIRISALRSLIDQLLLNGLDILQDKPVPPTSQTPDS-------PDISDRQPEKQAEEESPVQSILKMLSEFLD-SEVCELRTETAEGLAKLMYCGRILS-PKLLSRLVLLWYNPVTEDDQRLRHCLGVFLQLYARASRANQECVE---ESLLPTMRTLFNAPVTSPLSEVDASNVAELFVELTRPSALVQPAV----VQAVSVHDSLALRVCNEILRDVSAPE----VRLYCKTLSWLEINIEPGP-ANNELQLLLKDILQE-VKDKYCTRVIEKLCNQLIGDHGSKSASNQDTALLNLDENNGELMNKDE--------------------------------------------TKPKRAKRGQKKAATAKNGKKSYKADMSSDE------------SDEENIP-EEVPSVRPS---RRAKIAALDKTKQDLTALINQEANGS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z987-1", "uniprot_id": "A1Z987_DROME", "id": "A1Z987-1", "name": "Nuclear condensin complex subunit 3 C-terminal domain-containing protein", "aln": "MAKPKAKAGETEKPKTKAAGGKKRLAATKKTKKDGEKENEDQSVATTSDTSAELMYAIMRQAELKESLHKRYSKEMQQLYAKMGHESFRKAFINVLKAVLGAEEGNENANMALNFCATFVTSSDS------------DGTEP-----MLAETFHWLLTTYSSNP-HIRYRICYFVNLILKELGPNAALDDHQCDDILEAMLDRVKDVSASVRKQAVLAMQRLQNPD-----------NPSDVVVGAYMYHLTSDPSPNVRQCIITCMGRNYITIPHILERLWDVDEKVRRHTYVNMCN-YPVRSYKVAQR---LTLLEQGLNDTSATVRKTVINFMLKTWIESYQQNYVALIAALKLDSNEEELLRFRRVAKQMLRVIFQQTDIKQLIDQLPLSEDCELHRCIPHDSVTVELLLYWQCLSEYLETEAPE----IESLLPELSVFCTYMDKFCQ-------FQKPDMDKFAQVEFQNML-LSLVEILETYDLGDEIGRGNMRLLITNLLKDCLLDHKIVRVLVRCMEQLITDTNDRIQYFIEIIYELCELNTKQNDLIHDRSLINKLLDDLDTPLKMKISSLKVKILELEELEGNYVRQREYIRAQSVNDEKIAVTEEYTELIRPLLEKHGVIEMP--TRPKLSKQERVLKGLYISYYMTASPHVHK-LTPSLCQLYKDFICRYLPCAEVDIFEWSIKCGTTFSIFYEAYSREVFEVVVVQFCKNNNVRLCEASANCILELLDRYGVDYFNDLNQTGGSLSKTKRRQLYTMQELYDDDDGSQSQNNEQNSDILVVLGHYLERVQHRGVGMAIVRGLCRLVLRGHVDDRTDVLELLLKRYFNPNTEP--IINQVLGLFFEELRRLN--KHSLLQ---PCFLPTVWTCN---YDSPLHGVQPEHLTKFFLEMTVQEMSTPQTN---------IHNKIAISFLQYIQNYFTERKD--MCRLLAKELTNLSINVLNGPEVKAELLALAENLIQS-ELDPRMIKCIQNFKLVVNGSFNPPPRRNPDEGESDEEYETATVTTAESETAVPAQSQPPVTEESPNDVTQSAAITAVDATETPKAAAPPAPVPEPIVTTFGKDNIVGIRHLRRSMAISHSDAESLLGPQSPNPEESTESEAVETSKQNLRQPQMRRRLEMAIARSSKTPEKQPSTEEESSDEEISESPNAANKSNDSEVIEASPTAASPSPRAGHEASHLRIRSLRIRKVASTSTSQTTPKPVSKRKVVHLETPLRNGRKRVLRRSPSNSNSRSLRSRDSTALSSPRVSPRRKQQRLDNRSTRRQQMTKNTNSPTDSTSSVKENQIPPVIVIELDSDTESESNAKPESTPPKKPLKKTIPLIRSRPSSSTPKVTTRNEARAQRMNSKVMTRKRMSLEMNLSGGQLQVSTPKRVTRAVALSMSTDGKRSRRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06680-1", "uniprot_id": "CND3_YEAST", "id": "Q06680-1", "name": "Condensin complex subunit 3", "aln": "-----------MQDPDGIDINTKIFNSVAEVFQKAQGSYAG-------------------HRKHIAVLKKIQS----KAVEQGYEDAFNFWFDKLVTKILPLKKNEIIGDRIVKLVAAFIASLERELILAKKQNYKLTNDEEGIFSRFVDQFIRHVLRGVESPDKNVRFRVLQLLAVIMDNIG---EIDESLFNLLILSLNKRIYDREPTVRIQAVFCLTKFQDEEQTEHLTELSDNEENFEATRTLVASIQNDPSAEVRRAAMLNLINDNNTRPYILERARDVNIVNRRLVYSRILKSMGRKCFDDIEPHIFDQLIEWGLEDRELSVRNACKRLIAHDWLNALDGDLIELLEKLDVSRSSV--------CVKAIEALFQSRP-----DILSKIKFPES----IWKDFTVEIAFLFRAIYLYCLD--NNITEMLEENFPEASKLSEHLNHYILLRYHHNDISNDSQSHFD-YNTLEFIIEQLSIAAERYDYSDEVGRRSMLTVVRNMLALTTLSEPLIKIGIRVMKSLSINEKDFVTMAIEIINDIRDDDIE----------------KQEQEEKIKSKKINRRNETSVDEEDENGTHNDEVNEDEEDDNISSFHSAVENLVQGNGNVSESDIINNLPPEKEASSATIVLCLTRSSYMLELVNTPLTENILIASLMDTLITPAVRNTAPNIRELGVKNLGLCCLLDVKLAIDNMYILGMCVSKGN-ASLKYIALQVIVDIFSVHGNTVVD-------------------------------GEGKVDSISLHKIFYKVLKNNGLPECQVIAAEGLCKLFLADVFTD-DDLFETLVLSYFSPINSSNEALVQAFAFCIPVYCFSHPAHQQRMSRTAADILLRLCVLWDDLQSSVIPEVDREAMLKPNIIFQQLLFWTDPRNLVN-QTGSTKKDTVQLTFLIDVLKIYAQIEKKEIKKMIITNINAIFLSSEQDYSTLKELLEYSDDIAENDNLDNVSKNALDKLRNNLNSLIEEINERSETQTKDENNTANDQYSSILGNSFN----------------------KSSNDTIEHAADITDGNNTELTKTTVNISAVDNTTEQSNSRKRTRSEAE-------------QIDTSKNLENMSIQDTSTVAKNVSFVLPDEKSDAMSIDEEDKDSESFSEVC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .: . : : * . . *. * . :. : : : :.: : * :* . :: : :* : :*:* : :: .: :*: : : :: *: * ..** **.:.: ::*: : . . : : .*...:**:. : : . * . * * *:. *: .* : : :. : *:. **.* . :*::. : *:. : : : :: *.:. . :. :*. : : : . .* * : : : : : :*. :** . :: : . . : ::: .* * .:* ** : :: : * :. . :. : : : . *** :: ::: .:. : : : .: . . .:. . . :* : : . : : . : : : . :* : : : .: : : : :. .: : : . :.: : * .. .: :: . *. ..**.:*. . . . ::. *: ::.* .. : : :.. : ::. .. :: : . * : :: : : : : ::.: : . : : :: . :. : :. :* .:: : * . :::: : . : . . :. . . . .. * . . :: . : . * :: . ", "identical_positions": 61, "similar_positions": 285, "identity": "4.29%" }, { "cls_id": "homologset.agr.MGI:1930252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJM1-1", "uniprot_id": "SR5A3_RAT", "id": "Q5RJM1-1", "name": "Polyprenal reductase", "aln": "MAGWAGAELSVLN------PLRALWLLLAAAFLLALLLQLAPARLLPSCA-LFQDLIRYGKTKQSG--SRRPAVCRAFDVPKRYFSHFYVVSVLWNGSLLWFLSQSLFLGAPFPSWLWALLRTLGVTQFQALGMESKASRIQGKKLALSTFLVLVFLWVHSLRRLFECFYVSVFS-NTAIHVVQYCFGLVYYVLVGLTVLSQVPMNDKNVYALGKNLLLQARWFHILGMMMFFWSSAHQYKCHVILSNLR-RNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNVTWWLVVTYVFFSQALSAFFNHRFYKSTFVSYPKHRKAFLPFLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUP4-1", "uniprot_id": "SR5A3_MOUSE", "id": "Q9WUP4-1", "name": "Polyprenal reductase", "aln": "MAGWAGFELSALN------PLRTLWLALAAAFLFALLLQLAPARLLPSCA-LFQDLLRYGKTKQSG--SRRPAVCRAFDVPKRYFSHFYVISVVWNGSLLWLLSQSLFLGAPFPNWLSALLRTLGATQFQALEMESKASRMPAAELALSAFLVLVFLWVHSLRRLFECFYVSVFS-NAAIHVVQYCFGLVYYVLVGLTVLSQVPMDDKNVYVLGKNLLIQARWFHILGMVMFFWSSAHQYKCHVILSNLR-RNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNLTWWLVVTYVFSSQALSAFFNHKFYRSTFVSYPKHRKAFLPFLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8P0-1", "uniprot_id": "SR5A3_HUMAN", "id": "Q9H8P0-1", "name": "Polyprenal reductase", "aln": "MAPWAEAEHSALN------PLRAVWLTLTAAFLLTLLLQLLPPGLLPGCA-IFQDLIRYGKTKCGE--PSRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQ------------GGELALSAFLVLVFLWLHSLRRLFECLYVSVFS-NVMIHVVQYCFGLVYYVLVGLTVLSQVPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLR-KNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIU9-1", "uniprot_id": "SR5A3_DANRE", "id": "Q5RIU9-1", "name": "Polyprenal reductase", "aln": "-------MFHILS------IVNIIWLLLALCFGAAFCLNKFSVKLPNRVEHVFQDFIRYGKTKEN---IKRASWQLVFDLSKRYFYHFYVVSVMWNGLLLLFSIRSVVMSEAFPDWIIDVLGSLTGRSRG-----------AWNEIHLSTLLLQVLLWVHTLRRLLECLFVSVFS-DGVINVVQYAFGLSYYIILGLTVLCTNDSLPQSESVS---FFNQLTWYHVVGTLLFFWASFLQHQSLSLLAKMR-TDSSGKVETLAHKMPCGGWFELVSCPHYLAELLIYAAMCVCCGCASLTWWMVVLYVLCNQALAAQLCHEYYRSKFKTYPHHRKAFIPFVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40526-1", "uniprot_id": "DFG10_YEAST", "id": "P40526-1", "name": "Polyprenal reductase", "aln": "----------MYF------DEEQLLKYTIYAYRLSFFVGICSLFIAKSCLPEFLQYGKTYRPKENSKYSSILERIKKFTVPKAYFSHFYYLATFLSLVTLYFYPK---------------------------------------------FPIVWIIFGHSLRRLYETLYVLHYTSNSRMNWSHYLVGIWFYSVLLLILNISLYKN------------SIPNTLNMNAFIIFCIASWDQYKNHVILANLV-KYS----------LPTGRLFRLVCCPHYLDEIIIYSTLLP----YEQEFYLTLVWVITSLTISALETKNYYRHKFKDNHVAPYAIIPFII", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VLP9-1", "uniprot_id": "SR5A3_DROME", "id": "Q9VLP9-1", "name": "Polyprenal reductase", "aln": "MAPPENGILEVLENLLDRYKINLLQMMFGTFIATIVFFGGLMTFVEKYLPNSIRQSFRYGKHSFKG---ETDPLVAWLEVPKSWFKHFYTFALFWSWLAFYVLVSTVREQKEAPEYVLQFLDIMGGGRSHR----------KVEIDSTTACVGAFMLTLQCTRRFYETNFVQIFSKKSKINLSHYAVGYVHYFGAVIALLSNTSGFVRGSKPMEFS-LDKLTSQQILYLGVFFLAWQQQYASNMILVNLRKDPRTGSVKTEKHLLPKGGLFNLLSSPHMFLEVVMYFCIADLY-MPVRIWRLIFLWVASNQTINALLTHKWYQETFREYPKNRRAIIPFLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : : : : : . : :.* :* *** .: . . : :: : **: * :* :: . :: :* .* .* : : :: :* : *: :* :: :* * *. :...: : *:::* : : : . * . :: * :.:*: .* *::**::", "identical_positions": 27, "similar_positions": 69, "identity": "7.92%" }, { "cls_id": "homologset.agr.MGI:1930265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER64-1", "uniprot_id": "OSBL5_MOUSE", "id": "Q9ER64-1", "name": "Oxysterol-binding protein-related protein 5", "aln": "------------------------------------------MKEEAFLRRRFSLCPPASTPQKTDP-----------------------------------RKVPRNLLLGCENELGPITPGRDMESNGPSQPRDE----------------------------------EPQTPGSATKVPLAEYRLCNGSDKECTSPTTRVSKKDALKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP--KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQGSSPDASPSSLYGLPTSATIP-DQDLFPLNGSALEN----DAFSDKSERENAEDSD-AETQDHSRKTNESGSDLLDSPGGPWR-GTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLGKLSDYYYHGDLLSRAAAEDDPYCRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCRWLHPQTNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRK------EEYTLTMPYAHCRGILYGTMTMELGGKVNIECEKNNLQAELDFKLKPFFGSSANINQISGKIMSGEEVLARLTGHWDRDVFIKEESSGGTELFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIREGDQHKATQEKSVLEEAQRQRAREHQQSLTPWKPQLFLLDPLTQEWRYRYEDLSPWDPLKDIAQYEQDGILHTLQRETMSGQTTFLGSPDSRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGGESPCPRCRREVHRLKMLQEAVLSIQEAQQELHRHLSTMLSSTVRAGQAPAPSLLQNP---------------RSWFLLCIFLTCQLFINYILK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZYG1-1", "uniprot_id": "A0A8I5ZYG1_RAT", "id": "A0A8I5ZYG1-1", "name": "Oxysterol-binding protein", "aln": "-------------MCREQRWALVCGQKRLELLAPQKPPSTHTMKEEAFLRRRFSLCPPASTPQKTDP-----------------------------------RKLPRNLLLGCENELGPITPGRDMESNGPSQPRDE----------------------------------EPLTPGSATKVPLAEYRLCNGSDKECTSPTTRVSKKDTLKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP--KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGETVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQGSSPDASPSSLYGLPTSATIP-DQDLFPLNGSALEN----DAFSDKSERENADDSD-AETQDHSRKTNESGSDLLDSPGGPRR-GTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLSKLSDYYYHGDLLSRAAAEDDPYCRIKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWLHPQTNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRK------EEYTLTMPYAHCRGLLYGTMTMELGGKVTIQCEKNNLQAELDFKLKPFFGSSTSINQISGKITSGEEVLARLTGHWDRDVFIKEEASGGTKLFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIHEGDQHKATQEKSVLEEAQRQRAREHQQSLTPWKPQLFTLDPLTQEWRYQYEDYSPWDPLKDIAQYEQDGILHTLQRETMSGQTAFLGSPESRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGNESPCPRCRREVHRLRMLQEAVLSIQEAQQELHRHLSAMLRSTVRAGQAPAPGLLQNP---------------RSWFLLCIFLTCQLFINYILK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0X9-1", "uniprot_id": "OSBL5_HUMAN", "id": "Q9H0X9-1", "name": "Oxysterol-binding protein-related protein 5", "aln": "------------------------------------------MKEEAFLRRRFSLCPPSSTPQKVDP-----------------------------------RKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE----------------------------------GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP--KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN----DAFSDKSERENPEESD-TETQDHSRKT-ESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRA------EDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSP---------------RSWFLLCVFLACQLFINHILK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGK0-1", "uniprot_id": "E7FGK0_DANRE", "id": "E7FGK0-1", "name": "Oxysterol-binding protein", "aln": "------------------------------------------MKEENLFRRRFSLCPTATSPPKIDP-----------------------------------RVLTRNLSYGGDNELYPLSPGNETERNGLPLLRDE----------------------------------VSPARSPSS---VSESRMFIGLEKESSSPTEKLARKESLKVQKKNYRQEKKRVAKELFSALKDPSVVIMSNWLKIRGTLKSWTKLWCVLRPGILIIYKTP--GSDHWVGTILLNACKLIERPSKKDGFCFKLYHPMDKSIWAMKGPEGETVGSITQPLPSNYLIFRAASESDGRCWMDALELALSCSSLSKM-TAKSCRDGDLSSSSESS--HILQLLQSSALT-DQELLQLNDSMLENNMENDANSDKSEREAHEDSDNAANENGGRLTEESDMDQSDD---VCLQATGFVEEAHEEMGEAGEASQVETVSDENKGLIWTLLKQLRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADLLSKAVTEESPYGRMKQVLRWYLSGFYKKPKGLKKPYNPILGEMFRCCWLHPQTDSCTFYIAEQVSHHPPVSAFYISNKKDGFCISGSILAKSKFYGNSLSAILDGKARLLFLTRD------EEYVITMPYAHCKGILYGTMTLELGGKITIECEKTQCYTELEFKLKPFLGSSCNVNQISGKIRIGEDILATVEGHWDSKVHLIEKKTGHQEVLWNPGPDIRRQRLKKRVVPIDQQEAFESERLWQHVTQAINDKDQNRATQEKFVLEEAQRQEARERAER--AWNPRLFTLDADTNEWHYKHADTKPWDPERCLVQFEKDGIIQTKEKSQRRRNRYSYSQDWAGQQKVRVNGKHRKSSSQPSSCSQNTESSSTTPEPNHESSDN-------EGFMNQCARCSKEVKDIALIEASVAAIQKTQQDIQRNLSALGRQIARHKTAEESKSLSG----------------RHFLILCMLLLFQLLINHVFT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4JCZ0-1", "uniprot_id": "A0A0B4JCZ0_DROME", "id": "A0A0B4JCZ0-1", "name": "Oxysterol-binding protein", "aln": "MQQPATPSTPVNNAPSATPSAASGPAASAPAVASSTPIRINSAKQQGAAGGGDTLAHPATPHSHSMPGTPHQQPQSSSVPTGGHLLQLQAPLPSAGGGTGAGAVTPSGLSMGASNQSLGVSVGAASSVSGISITPPNSAGLRQSTVFDFKFKRRPSLKVLMTKLPSTDSLSNSPAPSSPGIANWASDNRDGNVADKSAADAAKLNRKESYKAQRKNYRREKKRVASELMNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQKTKSSHWVGTVMLTSCQVIERPSKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFRAPSQAAGKCWMDALELSLRCSALLLRSNSSTGTAPTSSYIGEPLPVSHETQWSEADYEKHFNDHDLDADSQNE----APNAVMSGLESESESDPAEPAQDDVVDQQCVE-------------TSYVPFTEEEFGEQGE--QVEELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHP-SGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRG------ECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADATNVVVGKIKLGKETLATINGHWDKECRVKDSKTGEETVLFKVDAETRSKRLTRYMVPLDLQEANESQRLWQRVSEAIANEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFELDSYG-QWLYKYADLRPWDSRNDVRQYECQ--FKVLTQTRHKSVPIVHGAEMIHPLRSSIETLSRTQRQSPAGQPLPPGGSAVPKAKNKSLVLAPRDTNSDSSQSPQGAVKRSSSSAIKQLALAVDQVNRVLEQHTRQLNEISQRLERMQYSPPPSSMSAHSLHMLGGGVSQSTVIKSLIYALIGLAFSLILRWLFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02201-1", "uniprot_id": "OSH6_YEAST", "id": "Q02201-1", "name": "Oxysterol-binding protein homolog 6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSKKLTVGSDSHRLSKSSFSSNKSSHS------------------------------------------------------------------------------ATKDQPIDTD-----------------------------------------------DIDEDDESGHNIILNIISQLRPGCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLP-NKQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIELGDHMIIKSP--NFQADIEFKTKGYVFGTYDAIEGTVKDYDG-NAYYEISGKWNDVMYLKDLKQPRSSPKVFLDTHKESP-LRPKVRPLSEQGEYESRKLWKKVTDALAVRNHPVATEEKFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKPGEDLDYCIYKNIPVDEDPEKQIRSILQIAPILPGQQFTDKFFIPAFEKIKSQKKMIENEKQNPAKQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. ::*: : *.. : . .*.: : : ::* ::: :..:.:: :: *:*** **:::.****:** :*:* :::: . ::* :* *... *: *::***:.:: **.:*** **:*** * . * * . . ::**:**.***** .*:. :..: : : .**:* *** :*:::* : : :* * *. * * .: :*:* *.: :***.:: *:. ::::** * :. .: * * : : *:*: : : . . . * :. * **.:**::*: *: :: **:** :*: ** *::: . * ** . : * . * * . . : : :. .. ", "identical_positions": 99, "similar_positions": 141, "identity": "9.72%" }, { "cls_id": "homologset.agr.MGI:1930269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GM86-1", "uniprot_id": "A0A8I6GM86_RAT", "id": "A0A8I6GM86-1", "name": "", "aln": "MIGFCALGFLVFSLKRSRRSFLLLLLLLLLLNRFLQVMAMLQSHSRQSLNSFNCAL-GEYRSSDLCCKLCPAGMFVQEPCTIPHTQGRCETCPPGSFSRSANDLNSCIPCSTCTKEQEMVADCSATSDRVCQCQTGHYYYDPEVPEFCCPCTTCPQGIPALQECNPTNDTVCRQSASSKTE------AMIESGKKLVDHATLKMKPVTSCEFQANLCYILSSRPAWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER63-1", "uniprot_id": "TNR23_MOUSE", "id": "Q9ER63-1", "name": "Tumor necrosis factor receptor superfamily member 23", "aln": "MVTFS----HVSSLS---HWFLLLLLLNLFLP---VIFAMPESYS------FNCPD-GEYQSNDVCCKTCPSGTFVKAPCKIPHTQGQCEKCHPGTFTGKDNGLHDCELCSTCDKDQNMVADCSATSDRKCECQIGLYYYDPKFPESCRPCTKCPQGIPVLQECNSTANTVCSSSVSNPRN------WLF-----------LLMLIVFCI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P718-1", "uniprot_id": "A0A8M1P718_DANRE", "id": "A0A8M1P718-1", "name": "", "aln": "----------MDKSEAMKVCMALVIFSLALVGHGAAELGVSADHQNRTARQMTCLENHEYPHNGFCCKNCEAGTYVKEKCTSGQVMGKCSPCEKGTYAEHPTGMEQCLQCSQCHRDQTVVAECTSTSNTKCDCKIGTFCLPDEPCEVCKKCTKCKADEEEVSGCTPTSNTKCRRRPSHPTEGPTEKPSASNSTGTIFVIVSILILLVICAIVGAILFLKRRQRQQSETDGNLEEVKVPIDECPRSEEEQENSRNAGLEKEEEHRPESRPLLTQETQETGSKSIPVEDEDRGLGDSLPNTTSSSQTSLSALPQIIGDSPRSSPPAQRPTDRDQTESWPREDDPPRKLLPLLGEEESLSKSFDLFDSLDVRYHNKFFRSIGVSDNSIKLAETQQPMDKVYDLLRVWMQKEGLRANINTLLQALLDLDQRYSAEHIASKAVERGYYKYE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : *::: :: :.: .:. :.* ** ...*** * :* :*: *. :. *:*. * *::: ..:..* ** * ::* :**:*::**: *:*: * : : * * **.* . :. *..* :* * * : : : * . ", "identical_positions": 39, "similar_positions": 58, "identity": "8.74%" }, { "cls_id": "homologset.agr.MGI:1930270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GM86-1", "uniprot_id": "A0A8I6GM86_RAT", "id": "A0A8I6GM86-1", "name": "", "aln": "MIGFCALGFLVFSLKRS---RRSFLLLLLLLLLLNRFLQV-MAMLQSHSRQSLNSFNCALGEYRSSDLCCKLCPAGMFVQEPCTIPHTQGRCETCPPGSFSRSANDLNSCIPCSTCTKEQEMVADCSATSDRVCQCQTGHYYYDPEVPEFCCPCTTCPQGIPALQECNPTNDTVCRQSASSKTE------AMIESGKKLVDHATLKMKPVTSCEFQANLCYILSSRPAWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER62-1", "uniprot_id": "TNR22_MOUSE", "id": "Q9ER62-1", "name": "Tumor necrosis factor receptor superfamily member 22", "aln": "MFGFFCS--LVSSLSRWFLWRR--LLLLLLLLLLNLPLQVKFAMLELHS------FKCPAGEYWSKDVCCKNCSAGTFVKAPCEIPHTQGQCEKCHPGTFTEKDNYLDACILCSTCDKDQEMVADCSATSDRKCQCRTGLYYYDPKFPESCRPCTKCPQGIPVLQECNSTANTVCSSSVSNPRN------RLF-----------LLLSPLSVLIVSVVVFRIIRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P718-1", "uniprot_id": "A0A8M1P718_DANRE", "id": "A0A8M1P718-1", "name": "", "aln": "-------------MDKSEAMKVCMALVIFSLALVGHGAAELGVSADHQNRTARQMTCLENHEYPHNGFCCKNCEAGTYVKEKCTSGQVMGKCSPCEKGTYAEHPTGMEQCLQCSQCHRDQTVVAECTSTSNTKCDCKIGTFCLPDEPCEVCKKCTKCKADEEEVSGCTPTSNTKCRRRPSHPTEGPTEKPSASNSTGTIFVIVSILILLVICAIVGAILFLKRRQRQQSETDGNLEEVKVPIDECPRSEEEQENSRNAGLEKEEEHRPESRPLLTQETQETGSKSIPVEDEDRGLGDSLPNTTSSSQTSLSALPQIIGDSPRSSPPAQRPTDRDQTESWPREDDPPRKLLPLLGEEESLSKSFDLFDSLDVRYHNKFFRSIGVSDNSIKLAETQQPMDKVYDLLRVWMQKEGLRANINTLLQALLDLDQRYSAEHIASKAVERGYYKYE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: : *::: * *:. . : :. ** ...*** * ** :*: * :. *:*. * *:::. . :: *: ** * ::* :**:*::**: *:*: * : : * * **.* . :. *..* :* * * : : : : . . : ", "identical_positions": 40, "similar_positions": 55, "identity": "8.91%" }, { "cls_id": "homologset.agr.MGI:1930618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8Z6-1", "uniprot_id": "G3V8Z6_RAT", "id": "G3V8Z6-1", "name": "Krev interaction trapped protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNPENIEDVYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETK------LQGNSEIAQGILDYVVETTKPISPANQGIKGKRVVLMKKFPLDGEKTGREAALFIVPSVVKDNTKYAYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIP-----------ALFRPSPLERIKTNVIN-PAYAAELGQIENSL-----HMGYSALEIKSKMLALEKADTCIYNPLFGSDLQYTN----------RVDKVVINPYFGLGAPDYSKIQIPKQEKWQRS------MSSVVEDKERQWVDDFPLHR-----------------NACEGDSELLSHLLDKG-------------------FSVNQLDNDHWAPIHYACWYGKVEATR---------------------------------------------------------------ILLEKGKCNPNLLNGQLSSP--LHFAAGGGHSEIVQILLTHPDIDRHITDQQGRSPLNVCEENKQNNWEEAAKLLKEAI-----NKPYEKVRIYRMDGSYRSVELKHGNN--TTAQQIMEGMR-----------------LSQETQQCFTIWICSENLS----------------------------------------------------------------------------------LQFKPYHKPLQQVRDWPEILAELTNLDPQRETPQLFLR------------------------RDVGLPLEVEKKIEDPLAILILFDEAR-YNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEE---NLKSIVPITKLKSKAPHWINRILHEYKNLSMSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSN--------------------HKVIPVYVGVNIKGLHLLNMETKALLISLKYC--------------------CFTWQLGDAGTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQLMPSERNS--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6S5J6-1", "uniprot_id": "KRIT1_MOUSE", "id": "Q6S5J6-1", "name": "Krev interaction trapped protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETK------LQSNSEIAQGILDYVVETTKPISPANQGIKGKRVVLMRKFPLDGEKTGREAALFIVPSVVKDNTKYAYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIP-----------ALFRPSPLERIKTNVIN-PAYAAELGQVDNSL-----HMGYSALEIKSKMLALEKADTCIYNPLFGSDLQYTN----------RVDKVVINPYFGLGAPDYSKIQIPKQEKWQRS------MSSVVEDKERQWVDDFPLHR-----------------NACEGDSELLSHLLDKG-------------------LSVNQLDNDHWAPIHYACWYGKVEATR---------------------------------------------------------------ILLEKGKCNPNLLNGQLSSP--LHFAAGGGHAEIVQILLTHPDIDRHITDQQGRSPLNVCEENKQNNWEEAAKLLKDAI-----NKPYEKVRIYRMDGSYRSVELKHGNN--TTAQQIMEGMR-----------------LSQETQRYFTIWICSENLS----------------------------------------------------------------------------------LQFKPYHKPLQQVHDWPEILAELTNLDPQRETPQLFLR------------------------RDVGLPLEVEKKIEDPLAILILFDEAR-YNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEE---TLKSIVPITKLKSKAPHWINRILHEYKNLSLSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSN--------------------HKVIPVYVGVNIKGLHLLNMETKALLISLKYC--------------------CFTWQLGDAGTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQLMPSERNS--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00522-1", "uniprot_id": "KRIT1_HUMAN", "id": "O00522-1", "name": "Krev interaction trapped protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETK------LQGNSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDNTKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIP-----------ALFRPSPLERIKTNVIN-PAYATESGQTENSL-----HMGYSALEIKSKMLALEKADTCIYNPLFGSDLQYTN----------RVDKVVINPYFGLGAPDYSKIQIPKQEKWQRS------MSSVTEDKERQWVDDFPLHR-----------------SACEGDSELLSRLLSER-------------------FSVNQLDSDHWAPIHYACWYGKVEATR---------------------------------------------------------------ILLEKGKCNPNLLNGQLSSP--LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAI-----NKPYEKVRIYRMDGSYRSVELKHGNN--TTVQQIMEGMR-----------------LSQETQQYFTIWICSENLS----------------------------------------------------------------------------------LQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLR------------------------RDVRLPLEVEKQIEDPLAILILFDEAR-YNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEE---NLKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSN--------------------HKVIPVYVGVNIKGLHLLNMETKALLISLKYG--------------------CFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQLMPTERNS--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1REV3-1", "uniprot_id": "KRIT1_DANRE", "id": "F1REV3-1", "name": "Krev interaction trapped protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNQE-LEEVFVAVIRPKNTTSLNSKEYRAKSYEILLIEVPLEGKEKKRKKVLLGTK------IHADSDRTKSILEFVDETTKPIS-NNQGIIGKRVVHMRKFLLDGDSGGKEASLFIVPINVKDNSKSVHHPGSPSFYCLQDIMRVCSETSAHFSSSTSKMLLALDKWLAEQHTVPHAIP-----------ALFRPAPVDRVKTNVSN-PAYAVEK-QTDGTL-----HMGYTALEIKSKLMSLEKADLCIQNPLYGSDLQYTN----------RVDKVIINPYFGLGAPDYSKIQIPKRDKWQHS------MTSVTEDKERQWVDDFPLHR-----------------SACEGDTELLSKLLDGG-------------------FSVKQLDSDHWAPIHYACWHGKVEATK---------------------------------------------------------------LLLEKGNCNPNLLNGQLSSP--LHFAAIGGHAEIVQLLLQHPEIDRHIEDQQKRSPLQVCEENKQNNWEETVNLLQQAS-----NKPYEKVRIYRMDGSYRSVELKHGNN--TTVQQIMEGMR-----------------LSQETQQYFTIWICSENLS----------------------------------------------------------------------------------LQLKPYHKPLQHLRMWSEIVTDLTALDPQRESPQLFLR------------------------RDVRLPLEVEKKVEDPLSILILFDEAR-HCLLKGFLSTSDNKLITLASLLLQIIYGNYDSKKHKQGFLNEE---NLKSIVPISKVKSKAHHWTNRILHEYKSLSTSEGVSKEMHHLQRLFLQNCWDIPTYGAAFFTGQVFTKASSST--------------------HKVIRVYVGVNTKGLHLMNMETKVLHLSLEYG--------------------TFMWQLGQADQYVQIHSLENKKNFVVHTKQAGLIVKLLMKLSGQIAPNDRAVSDKYAYG-------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7EZL0-1", "uniprot_id": "E7EZL0_DANRE", "id": "E7EZL0-1", "name": "Serine/threonine-protein kinase LMTK2", "aln": "MEALLGGGVCFLGFVTLTHAAPVSNTLSAEAAGYVDVSLSIPLLLSLAVTLALVVLLLNCASCCKEQEINFKEFEDHFEDEVDFTPPAEDTPSMQSPAEVYTLAVPPVHLPGPPHLQLPRITDVSSGPHVARHSLSYIQEIGNGWFGKVLLSEIYVDPGVARAVVRELKANASSKEQNEFLQQGDPYRVLQHPNILQCLGQCVEAIPFLLVFEYCELGDLKSYVSQHEWLYRNGELLQLQKMACEIAAGVTHMHKHNFLHSDLALRNCFLTTDLTVKVGDYGIGPTNFKEDYITTEDDQCVALRWLSPELIGELHGGLITSEQTKPSNVWALGVTIWELFECAKQPYHHLSDREVLHHVLKDQQVRLLKPQLDLPYSERWYEVLQFCWLPADKRATAEEVHRLLTYLRMQGQKDVEDDFEQRWSSLKPNPSTRQATVSHSSFPILEQFDDGREPDEVLTVTETSRGLSFEYVWEAAKHDHYDSHNRSAMDTTLNYHSMFFPVPRQDIQAHFPDTTAQAADGGRVPETLPVFDAHKASSGNDYFIKLEELDESEIGMGDSQGAEGTNTSEQNQYVVLQDVRLDESSTDADFFHQSIDSKDSFLQDSHIWSSSEHDSPYHTNIFSEGDAKMEDSHSFEGGFMELPEMMNLPKRDSDEANGKEASFQTSFLGVGPEAIHLEISDQGSSDVMKLLNTEKLSDNFMFLKDNSLMKDKSEVSPPDSINIKRSIIETNVSDSVNLTGESLKSAGSSAQLKDEFLDLVSPILDDFLSPLKGREAMVPFDILVTGSNRLPDTNGSLRSPKSRNYSSSESTSESVEVIVDSPSDSHQSLESATTDTLQMCIDAKPPSLEECFVASKDNGQHIGISDAAELSFTTSPVGEYTELGLTEGLTSSDSMSDIMETAKDIPPSEAIDQDTLLDNHATQDMSSLLVLDSCLDQISQDSLLDDSTSSTLPTIENSAETPDSLDSLDVAHGQSLDISVNKLQPPYKAADSGYETENLESPEWNSQTGLKDEDNDAAVEPSALVPPEIVVSEVDSVPDVQVNAGGVDHQQEPGEFPLGGNYRDSAYFSDNEELDKKSDDVSGNGSSIWLQNNQETNESRVARALEEHSRSETSSQSAGPTVESTITATKTLVPELVLTTEEDWSKEKPLTVDDSNQNHPCDVPETPTTSLPPPTEVMLHAKLTRTYAGEGTKKKEPDMEGRYLGKLDGSYGTEDGMDADEEDENSDDSDEDMRAYRLHSSSSECSEDEVVHPVPIIISDNSSSLNLKSLLKPKTLQTAKATSEEGRDGDSRRGVSFFDDVTVYLFDQETPTKELSEHTLDPSSQLSDFSSPVASSSYLNRFTNSESSTDEEGGAFEWDDDFPSPEPNFLSKAASDHSSSRSSGTSAASKYFSPPPANRSLDQSWTSPSSYSRFSISPASIASFSLTHLTDSDMEQGGSGEDGEKD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : . .:* .::* . * .. :*:: : ..*: : * :: : : . . : :. ::. : : : ::*:. .: . : :. . . * *::: . .. : *:: * * :* . ::* * * : ::::. : .* *.: : :* * . :. : *: *:::: : :. ... : :: *:*: :. * : * .. : . . *. * :.: .: : : *...:. .* ::.: : :*. :..::*..:. . : .* *.: :* .*. . **.* ** :::: . :* *:::: *. .:: :. ..*::* : * . ** :: ... * *.* .: *..* . : .:*** : :*: . :.: * :::* : * . :..: .:: .: :* *:*. :: * .. : *: ::: ::. * :.:* :. .: : .: : :*: ::: . :. .::: : :: . . ** : .* . : : . .**..*: .:: :* : .: :.: ::. * : : : :. * ..*:* .: . : : : :: . .. *::: . .: .:. .. * ..: . :. ", "identical_positions": 83, "similar_positions": 299, "identity": "5.74%" }, { "cls_id": "homologset.agr.MGI:1930628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY79-1", "uniprot_id": "HGH1_RAT", "id": "Q6AY79-1", "name": "Co-chaperone protein HGH1 homolog", "aln": "MRGPGVGSGLSGERGLSGKEAGADTEVAELLPFLVPGARADLQAAAAQHVLALTGVGSGRTLLAGQTALLRALIDLAVAPIPAP---SRDASRALVNLAADP--DLHWQMLAADPELPVRLLRCVL----DPQWPWAEELAAVLANLSREP-----------APCAVLTEKLVAAEPERLGLERLVSALCMPSYN---------ASAPLHYLGPLLSNLSQQAEVRAFLLDPD----RCVVQRLLPLTQYTDSSVRRGGVVGTLRNCCFEHRHHKWLLGPQ-VDILPFLLLPLAGPE--EFSEEEMEELPVDLQYLSPDKQREPDADIRKMLIEAIMLLTATAPGRKQVRDQGAYLILRELYAWES----EPDVRMACEKLIQVLIGDEPEVGMEN-LLEVQVPEDVERQLQELDQQEQQ----ELAQERRDKGAPRT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3I8-1", "uniprot_id": "HGH1_MOUSE", "id": "Q8C3I8-1", "name": "Co-chaperone protein HGH1 homolog", "aln": "MRGPGVGSGFSGERGLLEQEAGADTEAVELLPFLVLGARADLQAAAAQHVLALTGAGSGRTLLAGQPELLRALVDLAVAPAPAP---SRDASRALVNLAADP--NVHWQLLAADPELPARLLRCVL----DPQWPWAEEAAAVLANLSREP-----------APCAALMEKLMAAEPERLGLERLVNALCTPSYN---------AAAPLHYLGPLLSNLSQQAEVRAFLLDPD----RCVVQRLLPLTQYTDSSVRRGGVVGTLRNCCFEHRHHKWLLGAQ-VDILPFLLLPLAGPE--EFSEEEMDQLPVDLQYLSPDKQREPDADIRKMLIEAVMLLTATAPGRKQVRDQGAYLILRELHSWEP----EPDVRMACEKLIQVLIGDEPEAGMEN-LLEVQVPEDVEQQLQELDQQEQQ----ELAQELRGNGAPHT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTY7-1", "uniprot_id": "HGH1_HUMAN", "id": "Q9BTY7-1", "name": "Co-chaperone protein HGH1 homolog", "aln": "MGEAGAGAGASG-----GPEASPEAEVVKLLPFLAPGARADLQAAAVRHVLALTGCGPGRALLAGQAALLQALMEL--APASAP---ARDAARALVNLAADP--GLHETLLAADPGLPARLMGRAL----DPQWPWAEEAAAALANLSREP-----------APCAALMAALAAAEPADSGLERLVRALCTPGYN---------ARAPLHYLAPLLSNLSQRPAARAFLLDPD----RCVVQRLLPLTQYPDSSVRRGGVVGTLRNCCFEHRHHEWLLGPE-VDILPFLLLPLAGPE--DFSEEEMERLPVDLQYLPPDKQREPDADIRKMLVEAIMLLTATAPGRQQVRDQGAYLILRELHSWEP----EPDVRTACEKLIQVLIGDEPERGMEN-LLEVQVPEDVEQQLQQLDCREQEQLERELAPEPWVERATPT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGR4-1", "uniprot_id": "HGH1_DANRE", "id": "Q6DGR4-1", "name": "Co-chaperone protein HGH1 homolog", "aln": "--------------------MLSEDEAKDLLSFLTLEMRADVKGQATGYILGLTGNRDGCRYLQSKPDFLKALVTLTSDPSIAI---VKDCFHALINLSADE--TLHQP-LVKETEILSKLIPKLQ----DPEFVFSDRICTILSNLSRHE-----------QTCRDVFKALQELN---VGLDRLVEIFCTEGFN---------KKASLHYLAPLLSNLTQLPEARHFILDKD----RCVIQRLLPFTQYEESITRRGGVVGTLRNCCFDYVHHEWLLSDA-VDILPFLLLPLAGPE--ELSEEENEGLPVDLQYLPEDKRREEDPDIRKMLLETLMLLTATKVGRQILKSKNVYPIMREFHKWEK----DPHVISACEKLVQALIGDEPEVGMEN-LMEVEIPKDVEEKLQELDAKEQEQMEKDKQELEKSQNESPEGLER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBG6-1", "uniprot_id": "HGH1_DROME", "id": "Q9VBG6-1", "name": "Co-chaperone protein HGH1 homolog", "aln": "-----------------------METVKELVQFMQPNQRLDLKAVALTHVLGLTGSSEGKSAILSLDEMLMAIFGLTFDANQTV---AKDAVLSLINLTSEEEAAIKVFQLAKQLQPPFAIVEVAAKEITNEQSDLADPWSMVLSNLTRVE-----------SLVHEILDTLERDD---HTLPRLAKAFAQLDYNK--------KKAKLHYLAPIFCNLTQVSRGRELCCHRK----YELLEKLLPFASFEGSVVRRGGTIGILKNVCFDTVYHDVILNEQ-SSILVAILQPLCGPE--EFSDEDNELLPIELQYLPESKTREEDPDLRKMLLECLLQLCSTRRSREILRSRGVYEILREYHKWEAKVGKDSDCLLACENVVDILIKKEEEIGLDNYKTEVEVPAEQSEKFVQEDAAYVK----SLLD--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48362-1", "uniprot_id": "HGH1_YEAST", "id": "P48362-1", "name": "Co-chaperone protein HGH1", "aln": "----------------------MTSQLNELVEFLHS-PQPAVRQIAIDNLVGFSAGPTSKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDK--LVRNIILSDDKKFLKFLVWKIV----DLTNPNADIMCILLSNLAKDDGILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKGYDKKLTKYASFNYLAFFFADISRFKLGRMYFIEEQEYDGVVPISKLLVFTEKYDAKVRREGVASTIKNSLFDSETHERLLKDEKINLLPYILLPIASAKDSEIDEEDMFNLPDELQLLPEDKERDPIPAIICCHLESILLLCTTHAGREYLRDKSVYPLVRELHKNVE----NEDIGELCYRIVNMLMRGEPGAGAVEEMPSKNAEEEEEEESEEEEDDDEED---EIVEVA------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: *: : :: * ::.::. . . : :. : . :: *:**: : :: * : :: : :: . *:**:: : * : * . . * ::**. ::.:::: * . . :.:** ::. : .** *. . ::* *: *. :* .:* :* *:...: ::.:*: ** :** *. .* *: . : :* :: * :* .*: ::.:..* ::** : : . * .::: *: * * : . : : ..: : : : . ", "identical_positions": 47, "similar_positions": 119, "identity": "10.63%" }, { "cls_id": "homologset.agr.MGI:1930638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20815-1", "uniprot_id": "CP3A5_HUMAN", "id": "P20815-1", "name": "Cytochrome P450 3A5", "aln": "MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLS--------YRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDP------------DVIRTVLVKECYSVFTNRRSLGPVG---------FMKSAISLAEDEEWKRIR--------SLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRRE---------AEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSR-----LNDKQKHRLDFLQLMIDSQN-----------SKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK--APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEING---------VFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQ-GLLQPEKPIVLKVDSRDGTLSGE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HB55-1", "uniprot_id": "CP343_HUMAN", "id": "Q9HB55-1", "name": "Cytochrome P450 3A43", "aln": "MDLIPNFAMETWVLVATSLVLLYIYGTHSHKLFKKLGIPGPTPLPFLGTILF--------YLRGLWNFDRECNEKYGEMWGLYEGQQPMLVIMDP------------DMIKTVLVKECYSVFTNQMPLGPMG---------FLKSALSFAEDEEWKRIR--------TLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQE---------AENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESR-----LKDKQKHRVDFFQQMIDSQN-----------SKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK--APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEING---------VFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNL-PILQPEKPIVLKVHLRDGITSGP--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64581-1", "uniprot_id": "CP3AI_RAT", "id": "Q64581-1", "name": "Cytochrome P450 3A18", "aln": "MEIIPNLSIETWVLLATSLMLFYIYGTYSHGLFKKLGIPGPKPVPLFGTIFN--------YGDGMWKFDDDCYKKYGKIWGFYEGPQPFLAIMDP------------EIIKMVLVKECYSVFTNRRCFGPMG---------FMKKAITMSEDEEWKRLR--------TILSPTFTSGKLKEMFPLMRQYGDTLLKNLRRE---------EAKGEPINMKDIFGAYSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFQIFDPFLLSVVLFPFLTPIYEMLNFSIFPRQSMNFFKKFVKTMKKNR-----LDSNQKNRVDFLQLMMNTQN-----------SKGQESQKALSDLEMAAQAIIFIFGGYDATSTSISFIMYELATRPNVQKKLQNEIDRALPNK--APVTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKDVEING---------VFIPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQPCEKTQIPLKISRQ-PIFQPEGPIILKLVSRD--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09158-1", "uniprot_id": "CP3AP_MOUSE", "id": "O09158-1", "name": "Cytochrome P450 3A25", "aln": "MELIPNLSIETWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGTIFN--------YYDGMWKFDEDCYKKYGKIWGFYEGPQPILAIMDP------------EIIKIVLVKECYSVFTNRRFFGPVG---------FMKKAITISEDEEWKRLR--------TLLSPTFTSGKLKEMFPIMRQYGDILVRNLRRE---------EEKGEPISMKDIFGAYSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSIFPRDSMNFFKKFVKRMKKER-----LASNQKNRVDFLQLMMNTQN-----------SKGQESQKALSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNK--APVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVEING---------VFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISRE-PIFQPEKPIILKVVSRDKPRTGS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N818-1", "uniprot_id": "A0A8M1N818_DANRE", "id": "A0A8M1N818-1", "name": "unspecific monooxygenase", "aln": "----MFFSAETWTLLAFLVALLVIYGSWPHRYFKKLGIPGPKTIPFFGTMLR--------YKDGFHVFDMDCFEKYGRIWGIYDGRQPVLCIMDQ------------TIIKTVLIKECYSLFTNRRNFRLNG---------ALYDAVSIAEDDDWRRIR--------SVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKT---------AKRGESADIKEFFGAYSMDVVTSTAFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSVTDFFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVDSQTGVK------HKSDGEHTEKGLSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETFPNQ--APVDYETLMSMDYLDAALSESLRLYPVAARLERVCKKTVEING---------LLIPKDLVVMVPTYALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFN-GLLSPKDPIKLKLQPRKLSQSPDVCNNNQKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W130-1", "uniprot_id": "CP9C1_DROME", "id": "Q9W130-1", "name": "Cytochrome P450 9c1", "aln": "-----MVFVELSIFVAFIGLLLYKWSVYTFGYFSKRGVAHEKPIPLLGNIPWSVLMGK--ESYIKHSIDLHLRLKQHKVYGVFNLRDPLYYLSDP------------ELIRQVGIKNFDTFTNHRKGITEGFND-----TSVISKSLLSLRDRRWKQMR--------STLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQ----LDAG----TSELELKDFFTRYTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISEFTFWG--GLKVMLYILMPKLMKALRVPVMDMNNVDYFKKLVFGAMKYR------KEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVV---NLREDDLVHINVGALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQLVLRYHLKPTDRTPADMMSSISGFRLLPRELFWCKLESRGPA------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V6H1-1", "uniprot_id": "CP9H1_DROME", "id": "Q9V6H1-1", "name": "Probable cytochrome P450 9h1", "aln": "---MDQSMIALALFIILL-VLLYKWSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIGG--MPVLKKMIELHTKHTGSPVYGIYALRDAVFFVRDP------------ELIKLIGIKEFDHFVNHNS--MHNNIQ-----ESILSKSLISLRDGRWKEMR--------NILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQ----LELSQDA-SIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWS--VVKAMLYALFPRLMKVLRIQVLDTKNIDYFSSLVTAAMRYR------QEHKVVRPDMIHLLMEAKQQRLADL--SDKSKDELYYSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLF---SARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESR--VYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRTSRDLLNDIRGHGLKPKNGFWLKFEARQ--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG82-1", "uniprot_id": "CP9F2_DROME", "id": "Q9VG82-1", "name": "Probable cytochrome P450 9f2", "aln": "-----MLWEFFALFAIAA-ALFYRWASANNDFFKDRGIAYEKPVLYFGNMAG-MFLRK--RAMFDIVCDLYTKGGSKKFFGIFEQRQPLLMVRDP------------DLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMR--------STLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQD----DSRVQ---ENELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQ--SMKFMLFFALKGLNKILKVELFDRKSTQYFVRLVLDAMKYR------QEHNIVRPDMINMLMEARGIIQTEK--TKASAVR----EWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITF--DVDGQKV---EVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFWIKLVQRN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A2U8U1P3-1", "uniprot_id": "A0A2U8U1P3_DROME", "id": "A0A2U8U1P3-1", "name": "", "aln": "-----MLWEFLALFAIAT-ALFYRWASANNDFFKDRGIAYEKPVLYLGNMAG-MFLRK--RAMLDIVCDLYTKGGSGKFFGIFAQRQPLLMVRDP------------DLIKQITIKDFDHFINHRNEFDTSSDDDPHDMSNLFSSSLFSMRDARWKDMR--------STLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQD----DSRVQ---ENELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQ--NMKFILLFALKSLNKILKVEIFDRKSTQYFVRLVLDAMKYR------QEHNIVRPDMINMLMEARGIIQTEK--TKASAVR----EWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKEL--------KYLDQVVSEVLRKWPPAIAFDRECNK--------------------------------------------------------------------------------EAKAVIYYLLKDYRFAPAKKSCIPLELISSGFQLSPKGGFWIKLVQRN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4I1-1", "uniprot_id": "CP9B2_DROME", "id": "Q9V4I1-1", "name": "Cytochrome P450 9b2", "aln": "-----MALIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAA-AALQK--SSFQRQLTEFYERTRQHKLVGFFNMRTPMITLNDP------------ELIKKVCVKDFDHFPNHQPFITSN--------DRLFNDMLSVMRDQRWKHMR--------NTLTPVFTAAKMRNMFTLMNESFAECLQHLDSS----SKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQ--FFKFMLSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYR------EKHNITRPDMIQLLMEAK----------NESEDK-----WTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLF---DFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPRK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4I0-1", "uniprot_id": "CP9B1_DROME", "id": "Q9V4I0-1", "name": "Cytochrome P450 9b1", "aln": "-----MSFVEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAA-SALQK--ASFQKQISEFYNRTRHHKLVGLFNLRTPMIQINDP------------QLIKKICVKDFDHFPNHQTLNIPN--------ERLVNDMLNVMRDQHWRNMR--------SVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSS----QPIAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDPENEFHTIGKTLAFSRGLP--FLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVDAMQYR------EKHNITRPDMIQLLMEAK----------KESKDN-----WTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLF---EFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSRK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V674-1", "uniprot_id": "CP6G1_DROME", "id": "Q9V674-1", "name": "Cytochrome P450 6g1", "aln": "----MVLTEVLFVVVAALVAL-YTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENS-FGMHLSEIYNDPRLKDEAVVGIYSMNKPGLIIRDI------------ELIKSILIKDFNRFHNRYARCDPHG-------DPLGYNNLFFVRDAHWKGIR--------TKLTPVFTSGKVKQMYTLMQEIGKDLELALQ------RRGEKNSGSFITEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVAR--AKDFFVAFFLPKLVSLMRIQFFTADFSHFMRSTIGHVMEER------ERSGLLRNDLIDVLVSLRKEAAAEPS---KPHYA-----KNQDFLVAQAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEG-GGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFY-DYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIHLEIVNDRLYDQSAPSLQ----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRB3-1", "uniprot_id": "CP6V1_DROME", "id": "Q9VRB3-1", "name": "Probable cytochrome P450 6v1", "aln": "---MVYSTNILLAIVTILTGV-FIWSRRTYVYWQRRRVKFVQPTHLLGNLSRVLRLEES-FALQLRRFYFDERFRNEPVVGIYLFHQPALLIRDL------------QLVRTVLVEDFVSFSNRFAKCDGRS-------DKMGALSLFLAKQPEWREIR--------TRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERG-AIVSIKDVCDLYNTDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRPNVRR--IIDLFVIFYLPKLVPLLRPKLFTEPHAEFLRRVIQLVIEER------ERGGDLRNDLIEMLLTLKKEADLQQD---KSHFT-----HHRDFLAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRLTYEAVARMEFLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHA-ECYTRRGMPVFISNLAIHHDPKYWPDPDRFDPERFSAANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEICDRTVERIQFDAKFALLASEQRIYLKVDCL---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V675-1", "uniprot_id": "CP6G2_DROME", "id": "Q9V675-1", "name": "Probable cytochrome P450 6g2", "aln": "------MELVLLILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLMGLLNMRMS-PAEFISQLYNHPDAENEPFVGIHVFHKPALLLRDP------------EMVRNILVKDFAGFSNRYSSSDPKG-------DPLGSQNIFFLKNPAWKEVR--------LKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQ----PLHNERMRCFDLEAKELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLR--AAEFTLVFFLPHLVPFVRFKVVPAEATRFLRKTINYVMSER------EKSGQKRNDLIDILIEFRRSTQLAKASGIKDQFV-----FEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVES-GGQVTLKMIESLEFMQMILLEVLRMYPPLPFLDRECTSG---RDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLVRDALGV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4U9-1", "uniprot_id": "C6A13_DROME", "id": "Q9V4U9-1", "name": "Probable cytochrome P450 6a13", "aln": "-------MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHW-TDINLR-IYRKFRG-VERYCGYFTFMTKSLFIMDL------------ELIRDIMIRDFSSFADRGLFHNVRD-------DPLTG-NLLFLDGPEWRWLR--------QNLTQVFTSGKMKFMFPNMVEVGEKLTQACR------------LQVGEIEAKDLCARFTTDVIGSCAFGLECNSLQDPESQFRRMGRSVTQEPLHS--VLVQAFMFAQPELARKLRFRLFRPEVSEFFLDTVRQTLDYR------RRENIHRNDLIQLLMELGEEG-------VKDALS-----FEQ--IAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRN-NQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNL-------ILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLRMEGLERP------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54781-1", "uniprot_id": "ERG5_YEAST", "id": "P54781-1", "name": "C-22 sterol desaturase ERG5", "aln": "----MSSVAENIIQHATHNSTLHQLAKDQPSVGVTTAFSILDTLKSMSYLKIFATLICILLVWDQVAYQIKKGSIAGPKFKFWPIIGPFLESLDPKFEEYKAKWASGPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCNWVFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLS---------------KENNYEPQVFFHEMREILCALSLNSFCG-NYITEDQVRKIADDYYLVTAALELVNFPIIIPYTKTWYGKKTADMAMKIFENCAQMAKDHIAAG---GKPVCVMDAWCKLMHDAKNSN--------DDDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPN--------YTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPLS--EKIKVFATIFPKDDLLLTFKKRDPITGEVFE------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * : ... . : * : * *: . : : . : .: * . : . : . : : : .. : : : :: * . : : * ** . : . . . . . ", "identical_positions": 9, "similar_positions": 43, "identity": "1.54%" }, { "cls_id": "homologset.agr.MGI:1930643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51800-1", "uniprot_id": "CLCKA_HUMAN", "id": "P51800-1", "name": "Chloride channel protein ClC-Ka", "aln": "-------------------------------------------MEELVGLREGFSGDPVTLQELWG--------------PCPHIRRAIQGG----------------------------------LEWLKQK-------------------------------VFRLGEDWYFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTS-TDVTEYPLVESTESQILVGIVQRAQLVQALQAEPP----------------------------------------------------------------------SRAP--------------------GHQQ----------------------------CLQDILAR-------------------------------------------------------------------------------------------------------------------GCPT--------------------------------------------------------------------------EPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN----PPAPK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51801-1", "uniprot_id": "CLCKB_HUMAN", "id": "P51801-1", "name": "Chloride channel protein ClC-Kb", "aln": "-------------------------------------------MEEFVGLREGSSGNPVTLQELWG--------------PCPRIRRGIRGG----------------------------------LEWLKQK-------------------------------LFRLGEDWYFLMTLGVLMALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTS-TDVAKYPLVESTESQILVGIVRRAQLVQALKAEPP----------------------------------------------------------------------SWAP--------------------GHQQ----------------------------CLQDILAA-------------------------------------------------------------------------------------------------------------------GCPT--------------------------------------------------------------------------EPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTN----PPAPK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUB6-1", "uniprot_id": "CLCKB_MOUSE", "id": "Q9WUB6-1", "name": "Chloride channel protein ClC-Kb", "aln": "-------------------------------------------MEELVGLREGASKKPVPLQELWG--------------PCPRIRRNIQGG----------------------------------LEWLKER-------------------------------LFRVGEDWYFLVALGVLMALISYAMNFTIGRVVRAHKWLYREIGDGHLLRYLSWTVYPVALLSFSSGFSQSITPSSGGSGIPEVKTILTGVVLEDYLDIKNFGAKVVGLSCTLATGSTIFLGKLGPFVHLSVMIAAYLGRVRTKTVGEPESKTKEMELLAAGAAVGVATVFAAPISGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFHLLAVFNNEQETITSIYKTSFPVDIPFDLPEIFFFVALGAICGILSCGYNYSQRTFLFFLKANGFTSKLLATSKPLYSALAAVVLASITYPPGVGHFMASRLSMSEHLETLFDNNSWALMTKNSSPPWAAEPDPQKLWLEWCHPQLTVFGTLVFFLVMKFWMLILATTIPIPAGYFLPIFIYGAVIGRLFGEVLSVAFPEGIVAGGRVNPIMPGAYALAGAAAFSGAVTHTLSTALLAFEVTGQLVHALPVLMAVLAANAISQSFQPSFYDGTIIVKKLPYLPWIRGRQIGSHSVTVGHFMNCALTTLAKDMPLEQVIQVVIS-TDVTQYPLVETTESQTLVGVVKRTHLVQALQTEPA----------------------------------------------------------------------SWAP--------------------GQQP----------------------------CLQDILAN-------------------------------------------------------------------------------------------------------------------GCPT--------------------------------------------------------------------------QPVTLQLSLETSLHETHNLFELLNLQTLFVTSRGRAVGSVSWVELKKAISTLTN----PPAPK----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51802-1", "uniprot_id": "CLCKB_RAT", "id": "P51802-1", "name": "Chloride channel protein ClC-Kb", "aln": "-------------------------------------------MEEIVGLREGSPRKPVPLQELWR--------------PCPRIRRNIQGS----------------------------------LEWLKER-------------------------------LFRVGEDWYFLVALGVLMALISYAMNFAIGRVVRAHKWLYREIGDGHLLRYLSWTVYPVALLSFSSGFSQSITPSSGGSGIPEVKTILTGVILEDYLDIKNFGAKVVGLSCTLATGSTIFLGKLGPFVHLSVMIAAYLGRVRTKTVGEPENKTKEMELLAAGAAVGVATVFAAPISGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFHLLAVFNSEQETITSIYKTSFPVDIPFDLPEIFFFVALGAICGILSCGYNYCQRTSLFFLKSNGFTSKLLATSKPLYSALAAVVLASITYPPGVGRFMASRLSMSEYLETLFDNNSWALMTKNSSPPWSAEPDPQNLWLEWCHPQMTVFGTLVFFLVMKFWMLILATTIPIPAGYFLPIFVYGAAIGRLFGEVLSLAFPEGIVAGGKVSPIMPGAYALAGAAAFSGAVTHTLSTALLAFEVSGQIVHALPVLMAVLAANAICQSYQPSFYDGTIIVKKLPYLPWIRGRKIGSHLVTVGHFMNCTLTTLAKDMPLEEVIKVVIS-TDVTQYPLVETTESQVLVGIVKRTHLVQSLHTDSA----------------------------------------------------------------------SWAP--------------------GQQP----------------------------CLQDILAN-------------------------------------------------------------------------------------------------------------------GCPT--------------------------------------------------------------------------QPVTLQLSTETSLHETHNLFELLNLQLLFVTSRGRAVGSVSWVELKKAISTLTN----PPAPK----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VGH7-1", "uniprot_id": "CLCN2_DROME", "id": "Q9VGH7-1", "name": "Chloride channel protein 2", "aln": "MVYFGDRQRDRNRDRSNQKVERIIHDEEFGEENVELVDSEWADFEKFICQLRKRRNSAMSMEEELRHVQRHPKIKSHAFYPCPPPAENARDSDSSDDDDPIGYIDTLMYGRYTKDLGEFAKDEARKLKILEKRRKQEDKQRNKELLGKHSTRAKRVSSWIWRHTVARLGEDWVFLALLGIIMALLSFIMDKGISICTNARIWLYRDLTSQPFVQYIAWVSLPVCLILFSAGFVHLIAPQSIGSGIPEMKTILRGVQLKEYLTFKTLVAKVIGLTATLGSG--MPLGKEGPFVHIASIVAQLLSKLVTSFQGIYENESRNSEMLAAACAVGVGACFAAPVGGVLFSIEVTTTYFAVRNYWRGFFAAVCGATVFRLLAVWFQNADTVRALFLTNFTTEFPFDPQELFVFALIGLVCGLGGASYVWVHRRYVLFMRSNKRMNKFLQKNRFLYPGFLALLVSSISFPLGTGQFLAGELSTHEQVTQLFSNFTWSRDD--------LTVEQAAVVTHWMTSYTSVFGNLVIYTLFTFVVSIIASTIPVPSGMFIPVFKIGAGFGRLVGEFMAVTFPHGVRYGGRLSPIMPGGYAVVGAAAFSGSVTHTVSVAVIIFEMTGQITHVVPVMIAVLVANAVAALLQPSIYDSIILIKKLPYLPDLLPSSSGMYSIFVEDFMVRDVKYIWHGISYQKLKEVLKLNKTLRSLPLVDSPDNMILLGSVQRYELIKMIEKHIGREKRMEVAQKWQKEAQERALEEEKKKQEVELKMRRPSRFEVLPAPDILSLRQIANDEMLPPKKRAETMHGSLAPRKSILKKTNSFNLKTYAQPMGHSPSITPYTTITGNSEFRIRSAFEAIFKKSTTLQDVQPDPETGSLSPAASNHEVEVPRTPSTPGVSKKVQLPAQSNWDFVTDQIMLQVNPISTESNKMPAEKDFTDKALSNNGDSSKQSPSIKFKANKVADVNRSPQTAKRCSKIRFANEVGVNGSPTRTKCKIKPENVLGYSIEDVDETTNPESLAESIQKPKSVRLPRERVIDMSPEDQKQWELEEMLKPIDLQKANVHIDPSPFQLVERTSILKVHSLFSMVGINHAYVTKIGRLVGVVGLKELRKAIEDINSNSFVPPTRDEDADEKPAVEKPLLSTNSSDKAVDMTVTSMDSALSNSENCSDIEMEHIKHTDKGTVSLTMPPQESKQSPSADKSNTENGNHA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::: . ..:.::* *** . :.. *: *::: : *:**** ** **::***:* *: : ..*: ****:: . :::*::*. **.*: **:** : *:*.* ******:**:* ** *::** :*.: ***:**:.**. * : *** *****:: ::* *.:: *. * *.:::: *:*.*..****.: ****..******** :::*:* :********.*** :*:****: .: :*: ::: *.* .:.*** *:*.*. :* :**: ...* : :* . *:: * .*:* ..: :*..: :::::**::* ..*:*:*..** : : **.* :*: : : .* . ::**.*.:: ::.* : *:*:***:*:* *:*:* ** :***.** ::. **.*: ** .*****.**:.*******:****:*.*:: **::**:.*.:**::***.***:. ***:**. :::******* : . * : : * .** :. : :. . ::: :*: . : . ***::.:. *:* *:* .*:: :. . * ** *:. ***: . *.** :* .: * .*:: :.:.**.::.:: :**. ** ** *. *::***. :.. **: . ", "identical_positions": 255, "similar_positions": 254, "identity": "21.2%" }, { "cls_id": "homologset.agr.MGI:1930666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLR9-1", "uniprot_id": "HIG1A_MOUSE", "id": "Q9JLR9-1", "name": "HIG1 domain family member 1A, mitochondrial", "aln": "----MSTNTDLSLSSYD-------------------------------EGQGSKFIRKAKETPFVPIGMAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTLG-------------------MGYSMYQEFWANPKPKP------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VH49-1", "uniprot_id": "HIG1A_RAT", "id": "Q8VH49-1", "name": "HIG1 domain family member 1A, mitochondrial", "aln": "----MSTNTDLSLSSYD-------------------------------EGQGSKFIRKARETPFVPIGMAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTLG-------------------MGYSMYQEFWAKRKP--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AFI4-1", "uniprot_id": "A0A8I6AFI4_RAT", "id": "A0A8I6AFI4-1", "name": "", "aln": "----MSTNTDLSLSPYD-------------------------------EGQGSKFIRKAKEKPFVPIGMAGFTAIVAYGLYKLKSRGNTKMSIRLIHMRVAAQGFVVGGMTLG-------------------MGYFMYQEFWDKLKP--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y241-1", "uniprot_id": "HIG1A_HUMAN", "id": "Q9Y241-1", "name": "HIG1 domain family member 1A, mitochondrial", "aln": "----MSTDTGVSLPSYE-------------------------------EDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVG-------------------MGYSMYREFWAKPKP--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KEI1-1", "uniprot_id": "A0A0B4KEI1_DROME", "id": "A0A0B4KEI1-1", "name": "HIG1 domain-containing protein", "aln": "MYIHISENNTVAISLTDRLKASKLTRRGNKFSNLFKMSSNSLFETDEDVAQANKLSRKVKESPFMLVGIAGFVAAGLIGAYKYRNRGSMSTSVFLMQLRVAAQGTVVGCLTAG-------------------LAYTMAKEYLLHEEPKSNTRPDE------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03713-1", "uniprot_id": "RCF1_YEAST", "id": "Q03713-1", "name": "Respiratory supercomplex factor 1, mitochondrial", "aln": "-MSRMPSSFDVTERDLD------------------------------DMTFGERIIYHCKKQPLVPIGCLLTTGAVILAAQNVR-LGNKWKAQYYFRWRVGLQAATLVALVAGSFIYGTSGKELKAKEEQLKEKAKMREKLWIQELERREEETEARRKRAELARMKTLENEEEIKNLEKELSDLENKLGKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . :: : ..:: : :: *:: :* .. . : : *. : :: **. *. .: :. * * .: : ", "identical_positions": 8, "similar_positions": 34, "identity": "4.19%" }, { "cls_id": "homologset.agr.MGI:1930704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35779-1", "uniprot_id": "BHE41_RAT", "id": "O35779-1", "name": "Class E basic helix-loop-helix protein 41", "aln": "MDEGIPHLQERQLLEHRDFIGLDYSSLYMCKPKRSLKRDDTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLT--TLGHLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERSLKSPVQADLDAFHSGFQTCAKEVLQYLARFESWTPREPRCAQLVS-HLHAVAT------QLLTPQVTPGRGPGRAPCSAGAAAASGSER-------VARCVPVIQRTQPGTEP--EHDTDTDSGYGGEAEQ------------GRAAVKQEPPGDPSAAPKRLKLEARG----------------ALLGPEP-----------ALLGSLVALGGG--APFAQP--AAAPFCLPFYLLSP-SAAAYVQPWLDKSGLDKYLYP-AAAAPFPLLYPGIPA--------AAAAAAAAAFPCLSSVLSPPPEKAGSAAGAPFLAHEVAPPGSLRPQHAHSRTHLPHA-----VNPES-SQEDATQPAKDAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PV5-1", "uniprot_id": "BHE41_MOUSE", "id": "Q99PV5-1", "name": "Class E basic helix-loop-helix protein 41", "aln": "MDEGIPHLQERQLLEHRDFIGLDYSSLYMCKPKRSLKRDDTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLT--TLGHLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERSLKSPVQADLDAFHSGFQTCAKEVLQYLARFESWTPREPRCAQLVS-HLHAVAT------QLLTPQVPSGRGSGRAPCSAGAAAASGPER-------VARCVPVIQRTQPGTEP--EHDTDTDSGYGGEAEQ------------GRAAVKQEPPGDSSPAPKRPKLEARG----------------ALLGPEP-----------ALLGSLVALGGG--APFAQP--AAAPFCLPFYLLSP-SAAAYVQPWLDKSGLDKYLYP-AAAAPFPLLYPGIPA--------AAAAAAAAAFPCLSSVLSPPPEKAGATAGAPFLAHEVAPPGPLRPQHAHSRTHLPRA-----VNPES-SQEDATQPAKDAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0J9-1", "uniprot_id": "BHE41_HUMAN", "id": "Q9C0J9-1", "name": "Class E basic helix-loop-helix protein 41", "aln": "MDEGIPHLQERQLLEHRDFIGLDYSSLYMCKPKRSMKRDDTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLT--TLGHLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRCVQLIN-HLHAVATQFLPTPQLLTQQVPLSKGTG-APSAAGSAAAPCLERAGQKLEPLAYCVPVIQRTQPSAELAAENDTDTDSGYGGEAEARPDREKGKGAGASRVTIKQEPPGEDSPAPKRMKLDSRGGGSGGGPGGGAAAAAAALLGPDPAAAAALLRPDAALLSSLVAFGGGGGAPFPQPAAAAAPFCLPFCFLSPSAAAAYVQPFLDKSGLEKYLYPAAAAAPFPLLYPGIPAPAAAAAAAAAAAAAAAAFPCLSSVLSPPPEKAGAAA-ATLLPHEVAPLGAPHPQHPHGRTHLPFAGPREPGNPESSAQEDPSQPGKEAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01068-1", "uniprot_id": "ESM3_DROME", "id": "Q01068-1", "name": "Enhancer of split m3 protein", "aln": "-------------------MVMEMSKTYQYR--------------KVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSLQGVVAGVGSPPTSTS--TAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIELQT------QLLQQQQ-----------------------------------------------------------------------------------QQQQHQQQQIPQS----------------------------------------------------------------------------------------------------SGRLAFPLLG-------------GYGPAAAAAAISYSSFLTSKDELIDVTSVDGNALSETASVS----------------------SQESGASEPVWRPW----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: *. * : *: : *:*:*** ***:*: :****: * *: : :**** :****:.*:: *. . * ::* .. : .* :.:::*:**: .*.:: * * : :. : :::. :* : * *** * *: : . *: :. .**** . ..***** . **.*:. * . :: *.*. . . ** :.* :* ", "identical_positions": 64, "similar_positions": 74, "identity": "13.14%" }, { "cls_id": "homologset.agr.MGI:1930705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61266-1", "uniprot_id": "STX1B_HUMAN", "id": "P61266-1", "name": "Syntaxin-1B", "aln": "-----MKDRTQELRSAKDSDDE--EEVVHVD-RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGK-LAIFTDDIKMDS--QMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKI-MIIICCVVLGVVLASSIGGTLGL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61264-1", "uniprot_id": "STX1B_MOUSE", "id": "P61264-1", "name": "Syntaxin-1B", "aln": "-----MKDRTQELRSAKDSDDE--EEVVHVD-RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGK-LAIFTDDIKMDS--QMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKI-MIIICCVVLGVVLASSIGGTLGL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61265-1", "uniprot_id": "STX1B_RAT", "id": "P61265-1", "name": "Syntaxin-1B", "aln": "-----MKDRTQELRSAKDSDDE--EEVVHVD-RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGK-LAIFTDDIKMDS--QMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKI-MIIICCVVLGVVLASSIGGTLGL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "----MTKDRLAALHAAQSDDEEETEVAVNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLEEGN-SSVFTQGIIMET--QQAKQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKI-MILICLTVLGILAASYVSSYFM----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39926-1", "uniprot_id": "SSO2_YEAST", "id": "P39926-1", "name": "Protein SSO2", "aln": "MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVS--EEQEMELRRSLDDYISQATDLQYQLKADIKDAQRDGLHDSN------KQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "id": "P32867-1", "name": "Protein SSO1", "aln": "MSYNNPYQLETPFEESYELDE--GSSAIG-AEG-HDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVN--EEQASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDGIHDTN------KQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: . : *: ::..*. :.: .. ::::. *. :*: . *: .*. : *. :: :** :. ::: : . :::* .. ::*:::: :*. ::.*::. * : :** * :.::*:* :.. :*:: : . :* :* ::::**::::***.:: ** ::* ** ** .* * :* *: :**.: *: .. .*.**:* ***::** :* :: :: . : . ", "identical_positions": 51, "similar_positions": 112, "identity": "16.83%" }, { "cls_id": "homologset.agr.MGI:1930708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYM8-1", "uniprot_id": "A0A0G2JYM8_RAT", "id": "A0A0G2JYM8-1", "name": "", "aln": "MEMEQLTFRDVAVDFSPDEWECLDPPQQRLYRDVMVENYRNLVSVA-----------------------------------LSHHCTQNFSPEQILKYSFTKGTNGSCGLKSLYLREDCIYID--ESKAHHGRDMQCLITSNTKDVIDSRDQEHKTALTITPVRPDTLDEPSIYNCKYPQESFQHDLTLKESLEDLIDGLMFHPNSSIDKELRSRGLISTSDQIETFYTERSLLFSQQIAISYDPKHNSIDYGLPAIDPLSHSPNGDTDVWESPFMYKETSKDFSSESLLNNCND-IILEKSSQYNKICNDFDHCSSPNKYQYTLPKKPFNCDNFFTQCSKLSIHQ--YVQDNCYKSIDCDTMFNKTLNVITHKIQHSQKSYKCNECGKAFKYCSSYRKHRIIHTGEKPFKCKVCGKSFTQCASLKKHQRIHTGEKPYKCEECGRSFNHYSILGQHQRIHTGEKPYKCKQCGKSFTQCSSLQKHQVIHTGEKPFRCAECGKSFTQNSTLSQHQRIHTGEKPYKCEQCGKAFTQCSSLRKHQRIHTGEKPYKCEECGRAFNCRSSFTKHKRIHTGEKPYKCKDCDKAFIHCTNLTQHRRIHTGEKPYKCNECGKSFSQCSNLRKHERIHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1WWJ5-1", "uniprot_id": "Q1WWJ5_MOUSE", "id": "Q1WWJ5-1", "name": "", "aln": "MEMEQLTFRDVAVDFSPDEWECLDPPQQRLYRDVMVENYRNLVSVGEDSIPAELPTHCHHFMPFLSKMSAIACAFHKQYKPLSHHCTQNFSPEQILKYSFTEVTNGSYSLQHLYLREDCANVGGNKAAACHGRHKQCLITSNTK---DNRNQEQKTALKKPHARTDTFDEPCVYNCKYPQEIFQHDLTLKESWEDLIDRLIFHSSNFIDKELRNRGPISKSDQVESSYPGRAILFSQQIPVSCGQKHNTNDCGLPATDPLLHSQNLDTDIWETPYMYKEISKGFSSGSLLNSCNDVVILEKSGQRDKVQNDFDHCLSPNNHQCNLPKKLFNCDNFFTQCSKLTIQQCNYIQDNHYKSIDCDTMFNKTLNVTRRKIQHSKKSYKCNECGKAFKYCSSYRKHSIIHTGEKPYKCKLCGKSFTQCASLKKHQRIHTGEKPYRCEECGRSFNHYSILGQHQRIHTGEKPYKCKQCGKSFTQCSSLQKHQVIHTGEKPYRCAECGKSFTQNSTLSQHQRIHTGEKPYKCEECGKAFTQCSSLRKHQRIHTGEKPYKCEVCGRAFNCRSSFTKHKRIHTGEKPYKCKDCDKAFIHCTNLIQHQRIHTGEKPYKCNECGKSFSQCSNLRKHERIHT", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************************************. ********************: **** .*: ******* :. :: * ***. ********* *.*:**:****. . .*.**:***.:******** ********** ***** *:**... ******.** **.***:*: *. *::******.:* . ***: * **** *** ** * ***:**:*:**** **.*** ****.*** :*****.* :*: ****** ***::* .**** *************:*:* *:*** **************** :*****:********************* ********:***:************************:******************************************************:*******************************:*************************** *************************************** **:********************************", "identical_positions": 491, "similar_positions": 57, "identity": "78.06%" }, { "cls_id": "homologset.agr.MGI:1930715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62839-1", "uniprot_id": "UB2D2_RAT", "id": "P62839-1", "name": "Ubiquitin-conjugating enzyme E2 D2", "aln": "-MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62838-1", "uniprot_id": "UB2D2_MOUSE", "id": "P62838-1", "name": "Ubiquitin-conjugating enzyme E2 D2", "aln": "-MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62837-1", "uniprot_id": "UB2D2_HUMAN", "id": "P62837-1", "name": "Ubiquitin-conjugating enzyme E2 D2", "aln": "-MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25867-1", "uniprot_id": "UBCD1_DROME", "id": "P25867-1", "name": "Ubiquitin-conjugating enzyme E2-17 kDa", "aln": "-MALKRINKELQDLGRDPPAQCSAGPVGDDLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNELAREWTRKYAM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15731-1", "uniprot_id": "UBC4_YEAST", "id": "P15731-1", "name": "Ubiquitin-conjugating enzyme E2 4", "aln": "MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** ***.** ****:.*********::****:**** **** ******:*************::***:*******:**.******:.*******:*********** *.***********:****** **: *****:***:", "identical_positions": 116, "similar_positions": 21, "identity": "78.38%" }, { "cls_id": "homologset.agr.MGI:1930751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLV2-1", "uniprot_id": "TP4AP_MOUSE", "id": "Q9JLV2-1", "name": "Short transient receptor potential channel 4-associated protein", "aln": "MAAAPAAAGAGASRGRRLAATAAAWGGWGGRPRPGNILLQLRQGQLTGRGLVRAVQFTETFLTERDKLSKWSGIPQLLLKLYATSHLHSDFVECQSILKEISPLLSMEAMAFVTEDRKFTQEATYPNTYIFDLFGGVDLLVEILMRPTISIRGQKLKISDEMSKDCLSILYNTCVCTEGVTKRLAEKNDFVIFLFTLMTSKKTFLQTATLIEDILGVKKEMIRLDEVPNLSSLVSNFDQQQLANFCRILAVTISEMDTGNDDKHTLLAKNAQQKKSLSLGPSAAEINQAALLSIPGFVERLCKLATRKVSESTGTASFLQELEEWYTWLDNALVLDALMRVANEESEHNQAPTVFPSLGTSEEGGLPHTSARAQLPQSMKIMHEIMYKLEVLYVLCVLLMGRQRNQVHRMIAEFKLIPGLNNLFDKLIWRKHSASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNELSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEHILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQV-DMKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQRMEHSKKYPGFLLNNFHNLLRFWQQHYLHKDKDSTCLENSSCISFSYWKETVSILLNPDRQSPSALVSYIEEPYMDIDRDFTEE---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEL6-1", "uniprot_id": "TP4AP_HUMAN", "id": "Q8TEL6-1", "name": "Short transient receptor potential channel 4-associated protein", "aln": "MAAAPVAAGSGAGRGRRSAATVAAWGGWGGRPRPGNILLQLRQGQLTGRGLVRAVQFTETFLTERDKQSKWSGIPQLLLKLHTTSHLHSDFVECQNILKEISPLLSMEAMAFVTEERKLTQETTYPNTYIFDLFGGVDLLVEILMRPTISIRGQKLKISDEMSKDCLSILYNTCVCTEGVTKRLAEKNDFVIFLFTLMTSKKTFLQTATLIEDILGVKKEMIRLDEVPNLSSLVSNFDQQQLANFCRILAVTISEMDTGNDDKHTLLAKNAQQKKSLSLGPSAAEINQAALLSIPGFVERLCKLATRKVSESTGTASFLQELEEWYTWLDNALVLDALMRVANEESEHNQASIVFPPPGASEENGLPHTSARTQLPQSMKIMHEIMYKLEVLYVLCVLLMGRQRNQVHRMIAEFKLIPGLNNLFDKLIWRKHSASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNELSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEHILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQV-DMKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQRMEHSKKYPGFLLNNFHNLLRFWQQHYLHKDKDSTCLENSSCISFSYWKETVSILLNPDRQSPSALVSYIEEPYMDIDRDFTEE---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P2D2-1", "uniprot_id": "A0A8M1P2D2_DANRE", "id": "A0A8M1P2D2-1", "name": "", "aln": "--MATRGPGFSRTQTRR------------GKP-CKNIFHKIRQGQVTGEGLTRGSQVPVALLEERDKRAQWQGIPVLLRRLHKSSHPNSDLSKIHSIVMELSSLLSMEAISFVTEERKMPQESISPNTYTFDLFGGVDLFMEILMRPTLTIQQNTPTMSDDLIKDCLSVLYNCCICTEGVTKSLAAREDFVMYLFTLMSNKKVFLQTATLIEDILSVRKEIIQLEEIPNLDSLVQSFNQQQLANFCRILSVTISEPDVGVDDKHTLLARSTQQKT--STCPSHAENNQVALLNIPGFIERLCKLATRKVTEAA-DASARLELEDWHSWLDNALVLDTLMQLAIEEAEQ-------SSTESSDESSLSSSPLRHRLPQSMKIVHEIMYKVEVLYVLCVLLMGRQRNQVHRMLAEFKLIPGLNNLFDKLIWRKQ-PFGHILHRQNQSCDCSPEISFKIQFLRLLQSFSDHHENKYLLLSGQELNELSDIYLNANIFEMEALNNTDRNLVCDGKKGLLTRLISVMKKEPIDSSFRFWQARAVESFLRGTPSYADQVFLLRRGLLEHILYCIIDSGCKSHDVLQSYFDLLGELMKFNIDAFKRFNKYVTTEEKFQMFLTQINSSLVDSNMLVRCIVLSLDRFENETNDVKVVEVFSECRLLSYMAQVENRLLFLLRLISIINVQTLTQENVSCLNTSLVILMLARRRGKLPLYLSALREKEYSEKYPGCLLNNFHNLLRFWQHHYLNKDKDSTCLENSSCIPFTYWKETVSVLLGSGRSSRCAIATYIDEPYRDLDRDFMELSLETERTLFTSQTHPACGYNS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ..* . : ** *:* **: ::****:**.**.*. *.. ::* **** ::*.*** ** :*: :** :**: : :.*: *:*.******::****:**:.**: **** *********::*******::*: :. .:**:: *****:*** *:******* ** ::***::*****:.**.************.*:**:*:*:*:***.***..*:***********:***** *.* ********:.:***. * ** ** **.***.****:***********:*:: ** ***:*::*********:**::* **:*: .. :*:*..*. :. * :*******:******:*********************:********************: . . :** :**.*****:*::**********************..******* * *:*** *:**: ****.******:******:.****** :******************.*****:***:***********:** ***:*****************:*********:.*: ***:**.***************:.********:. *:**.**:******:*::** .:: **:***.**:************************: :***** *:. *:*:**** *************:***:**************.*:*******:**...*.* .*:.:**:*** *:**** * ", "identical_positions": 538, "similar_positions": 167, "identity": "65.69%" }, { "cls_id": "homologset.agr.MGI:1930765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE59-1", "uniprot_id": "D3ZE59_RAT", "id": "D3ZE59-1", "name": "", "aln": "-------MQRALPGARQHLGAILASASVVVKALCAVVLFLYLLSFAVDTG-CLAVT---------PGYLFPPN-FWIWT--LATHGLMEQHVWDVAISLATVVVAGRLLEPLWG-ALELLIFFSVVNVSVGLLGAFAYLLTYMASFNLVYLFTIRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVS-------VVPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHS-------------RGR----GDMADHFAFATFFPEILQPVVGLLANLVHGLLVKVKICQK--TVKRYDVGAPSSITISLPGTDPQDAE-RRRQLALKALNERLKRVEDQ--------------------------------------------------------------------------SAWPSMDDDEEEAGAKTDSPLPSEQASTPPGKGTAP------------ESTLITFEAAPLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUH1-1", "uniprot_id": "TM115_MOUSE", "id": "Q9WUH1-1", "name": "Transmembrane protein 115", "aln": "-------MQRALPGARQHLGAILASASVVVKALCAVVLFLYLLSFAVDTG-CLAVT---------PGYLFPPN-FWIWT--LATHGLMEQHVWDVAISLATVVVAGRLLEPLWG-ALELLIFFSVVNVSVGLLGALAYLLTYMASFNLVYLFTIRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVS-------VVPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHS-------------RGR----GDMADHFAFATFFPEILQPVVGLLANLVHGLLVKVKICQK--TVKRYDVGAPSSITISLPGTDPQDAE-RRRQLALKALNERLKRVEDQ--------------------------------------------------------------------------SAWPSMDDDEEEAGAKTDSPLPLEEASTPPGKVTVP------------ESSLITLETAPLL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12893-1", "uniprot_id": "TM115_HUMAN", "id": "Q12893-1", "name": "Transmembrane protein 115", "aln": "-------MQRALPGARQHLGAILASASVVVKALCAAVLFLYLLSFAVDTG-CLAVT---------PGYLFPPN-FWIWT--LATHGLMEQHVWDVAISLTTVVVAGRLLEPLWG-ALELLIFFSVVNVSVGLLGAFAYLLTYMASFNLVYLFTVRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVS-------VMPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHS-------------RGR----GDMADHFAFATFFPEILQPVVGLLANLVHSLLVKVKICQK--TVKRYDVGAPSSITISLPGTDPQDAE-RRRQLALKALNERLKRVEDQ--------------------------------------------------------------------------SIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAP------------ESSLITFEAAPPTL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMD2-1", "uniprot_id": "Q9VMD2_DROME", "id": "Q9VMD2-1", "name": "Transmembrane protein 115", "aln": "---MSAQLARNWPYIWQQLNALLHNTSPVITLICVVTTFGYLLSFSETAILLLSVT---------PGYILPNGKFWIWT--AFTFCFIELHWWEVAVDVVTVGLCGKMLEPLWG-QLEMFKFFALSNFGVSLLTTVYYLFYYMVTKNPTILFEVHIHGLAGYVAGICVAVRQIMPDHLIFKTRYGRLTNR-----NVPLTVLIMAIILWAIGLLDGTYPAMFASGSLVSWIYLRFYQHHP-------------NGR----GDSSESFTFVSFFPNVSQPFISVLVNPIYNCCLRAGVVKTPTPLRTISTASLTSVSVQMPGVDPHDIE-RRRQIALKALSERLKATDSSRHAQLPKSFPQQQQLQHHHHQHAPHQQQKHHSHGTGHSHSHGAGHSHSHGAGHSHGPGPAQMPQPDFLKSTGSASQLPITTSRAEPRMISTMSPIAIPMPAPPPKEGNVPGQGAESSSSGGVEATLINLDDVPTTSSMA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12239-1", "uniprot_id": "TM115_YEAST", "id": "Q12239-1", "name": "Transmembrane protein 115 homolog", "aln": "MQYSSRFLELNIPDSFLNINKIPDATKFITVTYICLTATLFCIRRSLYNKLVLEDPNLDYNLITSPLLQMVPSQIWRYPTSLVLSNFIDTKAWKVVVNLLNLIIGGSFIERNWNSSKEMFKFIIVLGSLTNVLIIMLTLLVSFFSN--KVRLDIPLDGNYTILIGFPIIYRQLLPETTIIHLKTPQFLAKNFRFKLLPIFVMFTMTVTQIIWFHHFAQLFSIWVTFFASWSYLRFFQKLAPLNCPSLPTTNSQGGQEILVGDASDTFQLIYFFPDLIKPILRPIFNFIYNVVVVKFKVIK--PFHDIDIDIGNTIAESRGAKKIMTVEERRRQLALQVLEERMVNP----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::. : :. : . : : : * . * : . :* :. ::: : *.*.:.: .: : * ::* *. *:: *: : . ..:* . *: : : : : :.* : *. : :* : : ::: :. :*: :: : : . . : ** ****:*: . *: ** :: * : ***:: :*.: : * ::. : . ..: . .::: . . . * ****:**:.*.**: ", "identical_positions": 43, "similar_positions": 103, "identity": "8.81%" }, { "cls_id": "homologset.agr.MGI:1930768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGC2-1", "uniprot_id": "D3ZGC2_RAT", "id": "D3ZGC2-1", "name": "AT-rich interactive domain-containing protein 3", "aln": "MILMSREPVCLLGCAQVES------HASLWVKPETVMEPLQQQQ-KQPQQTPLQMDAREKQGSHTREAQFLYAPKLGTQPALLS--------VTPGRPSGSP-------VLGPLGRVLPATPAARVSEQSNVNSEPEEEEGGLEDEDGDD---DVTEVAEKEAQAASKYFHMQKATRQEPRAAPMSSLLPAPGLPPQGQ-TKEDHTKDASKAPPSVPTAGQ-----------------------PS----WNLDEQLKQNGALAWSDDADGGRGR---------EISRDFAKLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRR--------------------PSYSSSLFGYSP--AAAAAAAAAAAAASAASAGAPALLSPPKIRFSILGLGSSSGTNTSSPRIPPASTLRKGDGVP----------------VPVPNRLAVSGPLAGQQAGNRTGTLEQLRERLESG------------------------------EPPEKKASRLSEEEQRLVQQAFQRN----------------------------------------------LFSMARQL-PMKIRINGR-EDRAETSAAALNLTTSNIGSINMSVDIDGITYTGVLFAQKPVVHLIAGSAPQSIGSSASSSSSSSSSSSSSHCSPSPTSSRGTPSAEPSTSWSL-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1N7-1", "uniprot_id": "ARI3B_MOUSE", "id": "Q9Z1N7-1", "name": "AT-rich interactive domain-containing protein 3B", "aln": "------------------------------MEPLQQQQ-QQQQQ-KQPQQPLLQMDAREKQGPQTRESQFLYASKLGTQPALLS--------ITPGRPSGSS-------VLGPLARVPPATPVARMSEQSNVNSEPEEEEGGLEDEDGDD---DVAEVAEKEAQAASKYFHMQKVTRQEPRATPMSSLLPVPGLSPQGQQTKEDHTKDASKAPPSVPTAGQ-----------------------PS----WSLDEQLKQNGALAWSDDADGGRGR---------EISRDFAKLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRR--------------------PSYSSSLFGYSPAAAAAAAAAAAAAAASAASAGTPALLSSPKIRFSILGLGSSSGTSASSPRIPPASTLRKGDGVP----------------VPVPNRLAVSGTLAGQQAGNRPGPLEHLRERLESG------------------------------EPPEKKASRLSEEEQRLVQQAFQRN----------------------------------------------LFSMARQL-PMKIRINGR-EDRAEPSAPALNLTTSNIGSINMSVDIDGTTYTGVLFAQKPVVHLIAGSTPQSIGSSASSSNSSS-----SHCSPSPTSSRGTPSAEPSTSWSL-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVW6-1", "uniprot_id": "ARI3B_HUMAN", "id": "Q8IVW6-1", "name": "AT-rich interactive domain-containing protein 3B", "aln": "------------------------------MEPLQQQQQQQQQQQKQPHLAPLQMDAREKQGQQMREAQFLYAQKLVTQPTLLS--------ATAGRPSGST-------PLGPLARVPPTAAVAQVFERGNMNSEPEEEDGGLEDEDGDD---EVAEVAEKETQAASKYFHVQKVARQDPRVAPMSNLLPAPGLPPHGQQAKEDHTKDASKASPSVSTAGQ-----------------------PN----WNLDEQLKQNGGLAWSDDADGGRGR---------EISRDFAKLYELDGDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRR--------------------PSYSSSLFGYSP-----------AAATAAAAAGAPALLSPPKIRFPILGLGSSSGTNTSSPRISPATTLRKGDGAPVT-------------TVPVPNRLAVPVTLASQQAGTRTAALEQLRERLESG------------------------------EPAEKKASRLSEEEQRLVQQAFQRN----------------------------------------------FFSMARQL-PMKIRINGRAEDRAEASAAALNLTTSSIGSINMSVDIDGTTYAGVLFAQKPVVHLITGSAPQSLGSSASSS-SSS------HCSPSPTSSRGTPSAEPSTSWSL-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IZF6-1", "uniprot_id": "A0A0R4IZF6_DANRE", "id": "A0A0R4IZF6-1", "name": "AT-rich interactive domain-containing protein 3", "aln": "MVDNSSSSKAQVPSLSQDSSLASAFSQAAFASSAGVKLEAVMEQLQRQQQAKLEMERKER---HLREAHILYAQQLAAQQAIMASARAQGAPLTPDFYSKNSRDRALKGGQGPLAARGPVKTASDLAHEEDAADEMDRGRGSEGDEDDDDEMMDGEDGSEEEESEGLEFLRKQSLALQQAAVGVPPYSFPVYTASPSAAKKRPLSPTTKVKDEPEDSLSDQQ------------------SFNTPNGMGDWNLDDSFKQNGNSSWNEEGDGGRSRG--------EASRDFAKLYELDNDPKRKEFLDDLFAYMQKRGTPVNRIPIMAKQVLDLYMLYKLVTEKGGLVEVINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKKGLSSPGELQAAIDSNRREGRR--------------------PGYSNSLYRFSP----------------SPSGAAPHLLSPPKMHLPATGHNELQAT--PSPALKKATVP---EDSP---------------ASMLPARLPLALALGHQQQLARAATLEQLRERLETGMG-----------------AGAVNAGPAVVEGPERKMARLAEEQQRLLQQAFQQN----------------------------------------------LLAMASQVNPTNLRMNNA-NTREEKQDLSLSISSNGSASITVSVEVNGIIYSGSLYAQKSGSVPTAVTAMFPGHTSTLSPGVAS--------SSSSSSSKGPDSVDPATGGSP-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24573-1", "uniprot_id": "DRI_DROME", "id": "Q24573-1", "name": "Protein dead ringer", "aln": "---MQLRVHPTMDCSGRSTSNIERDSDLGDDLSHGDRTDDEMRDCDSVDGEHHQLSAKAAIAARLSHTVSGGGGSFASPEPQTELPLSHHHQLPPNHPLNALG---SFMGIGGLHSIPNLQHSDVLEKLKMQVRDMKVGLMEQDYAAAAHAAAFGANMLPTTISSGFPLPHNSVAFGHVTSSPSGGNGSSYNGGTTPTNSSNSNATTNGGGTAGPGGTGGSGGGGGGGGGGGGGVGGHQFSFASPTAAPSGKEARHFAANSASNSSTSSEASNSSQQNNGWSFEEQFKQVRQLYEINDDPKRKEFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPSSITSAAFTLRTQYMKYLYPYECEKKNLSTPAELQAAIDGNRREGRRSSYGQYEAMHNQMPMTPISRPSLPGGMQQMSP--LALVTHAAVANNQQAQAAAAAAAAHHRLMGAPAFGQMPNLVKQEIESRMMEYLQLIQAKKEQGMPPVLGGNHPHQQQHSQQQQQQQHHHQQQQQQQSQQQHHLQQQRQRSQSPDLSKHEALSAQVALWHMYHNNNSPPGSAHTSPQQREALNLSDSPPNLTNIKREREREPTPEPVDQDDKFVDQPPPAKRVGSGLLPPGFPANFYLNPHNMAAVAAAAGFHHPSMGHQQDAASEGEPEDDYAHGEHNTTGNSSSMHDDSEPQQMNGHHHHQTHHLDKSDDSAIENSPTTSTTTGGSVG-----HRHSSPVSTKKKGGAKPQSGGKDVPTEDKDASSSGKLNPLETLSLLSGMQFQVARNGTGDNGEPQLIVNLELNGVKYSGVLVANVPLSQSETRTSSPCHAEAPTVEEEKDEEEEEEPKAAEEESHRSPVKQENEDVDQDMEGSEVLLNGGASAVGGAGAGVGVGVPLLKDAVVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . . ::. : : .: . .: : . ... * * : . : . . : . . : . : . . .. . .. ... *. . : *. . ..:.... * ::. :***::.**:********* :*******:**:*****.:**** **:** :****::****:*:** ***:**:******************.****** **:*.*******.******* *. ...: ** : :..:. : . * . .. : . : ** : *:: *:* :: . ::: .*::. .* : ::: . : * * : :. . . : . .. * .: : : * . *. :: ::: :. : .*. *:: ...* :. . ", "identical_positions": 117, "similar_positions": 151, "identity": "12.66%" }, { "cls_id": "homologset.agr.MGI:1930773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZP3-1", "uniprot_id": "PNKD_MOUSE", "id": "Q69ZP3-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILSGATANKASQNRTRALQSHSSPECKEEPEPLSPELEYIPRKRGKNPMKAVGLAW---------------------------------------YSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAGLAVAVDPSDPRAVQASIEK-ERVNLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVG-RLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGTAETMLSSLDTVLDLG------DDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRMERKSTCP-STLGEERAYNPFLRTHCLELQEALGPGPGPTSDDGCSRAQLLEELRRLKDMHKSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXB0-1", "uniprot_id": "D3ZXB0_RAT", "id": "D3ZXB0-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILSGATANKASQNRTRALQSHSSPECKEEPEPLSPELEYIPRKRGKNPMKAVGLAWAIGFPCGILFFVLTKQEVDKDRLKQMKARQNMRVSNTGEYSLYTRTWLGYLFYRQQLRRARNRFPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAGLAVAVDPSDPRAVQASIEK-ERVNLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVG-RLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGTAETMLSSLDTVLDLG------DDTLLWPGHEYAEENLGFAGVVEPENVARERKMQWVQRQRMERKSTCP-STLGEERAYNPFLRTHCLALQEALGPGPGPTSDDGCSRAQLLEELRRLKDMHKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N490-1", "uniprot_id": "PNKD_HUMAN", "id": "Q8N490-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPELEYIPRKRGKNPMKAVGLAW---------------------------------------YSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEK-EGVTLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVG-RLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLGLG------DDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKGTCP-STLGEERSYNPFLRTHCLALQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NM08-1", "uniprot_id": "F6NM08_DANRE", "id": "F6NM08-1", "name": "", "aln": "MALPEWTVYLLCIAS----VCGGFYICRVVKCARKSAWKNSQIAKLMARSEKP------LFWIA------------------------------------------------------YSLYTRTKLGYIFHKRQMKKARERYPTGHSRAQPTIINGIKIIPVPILLDNYSYVVIDTASNTAVVVDPADPQPVQACLEA-EGVALQAVLCTHKHWDHSGGNRALKRRYS------SCRVYGNAMDNIPGLTHPLLDKDTIDFGTQLHFRAFYTPGHTVGHMIYLLDGRAIGGPSSLFSGDLVFLSGCGRMFEGNASTMLSSLDTVGSLN------DDTLLWPGHEYAEDNLLFAADVEPGNVVREQKLQWVLQQRSQRLCTCP-STLLEEKQYNPFLRSHSQDLHQALGLQQKQDEDWTSYRARVLEELRRRKDIYKDR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05584-1", "uniprot_id": "GLO2_YEAST", "id": "Q05584-1", "name": "Hydroxyacylglutathione hydrolase, cytoplasmic isozyme", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MQVKSIKMRWESGG--------------------VNYCYLLSDSKNKKSWLIDPAEPPEVLPELTEDEKISVEAIVNTHHHYDHADGNADILKYLKEKNPTSKVEVIGGSKD-CPKVTIIPENLKKLHLG-DLEITCIRTPCHTRDSICYYVK-DPTTDERCIFTGDTLFTAGCGRFFEGTGEEMDIALNNSILETVGRQNWSKTRVYPGHEYTSDNVKFVR-KIYPQVGENKALDELEQFCSKHEVTAGRFTLKDEVEFNPFMRLEDPKVQKAAG-----DTNNSWDRAQIMDKLRAMKNRM---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12320-1", "uniprot_id": "GLO4_YEAST", "id": "Q12320-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------MKFLLQQIRNMHVKPIKMRWLTGG--------------------VNYSYLLSTEDRRNSWLIDPAEPLEVSPKLSAEEKKSIDAIVNTHHHYDHSGGNLALYSILCQENSGHDIKIIGGSKS-SPGVTEVPDNLQQYHLG-NLRVTCIRTPCHTKDSICYYIK-DLETGEQCIFTGDTLFIAGCGRFFEGTGRDMDMALNQIMLRAVGETNWNKVKIYPGHEYTKGNVSFIRAKIYSDIGQNKEFDALEQYCKSNECTTGHFTLRDELGYNPFMRLDDRAVRLAVG-----DTAGTYPRSVVMQELRKLKNAM---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : *: .* **.*:: : :**::* * . : * : *:: **:*:**:.** : . .: *.. . * :* . . .* *.. .: ** ** . : * :. . .:*:** :* :**** ***.. * :*: ... ::*****:. *: * :: .:: :: : : .. * ** :* :***:* . :: * * *: ::::** *: ", "identical_positions": 62, "similar_positions": 82, "identity": "14.12%" }, { "cls_id": "homologset.agr.MGI:1930780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61879-1", "uniprot_id": "MYH10_MOUSE", "id": "Q61879-1", "name": "Myosin-10", "aln": "---------------------------------------------MAQRTGLEDPE-RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS-HKGR--------------------------KDHN------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEG--FNNYRFLSNGY-IPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWK-DVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN------AIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLR-HWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSR-SGRRQLHIEGASLELSDDDTESKTSDVNDTQPPQSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JLT0-1", "uniprot_id": "MYH10_RAT", "id": "Q9JLT0-1", "name": "Myosin-10", "aln": "---------------------------------------------MAQRTGLEDPE-RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEKPPHIYAISESAYRCMLQDRKDQSILCTGESGAGKTENTKKVIQYLAHVASS-HKGR--------------------------KDHN------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEG--FNNYRFLSNGY-IPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGTSFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWK-DVDRIVGLDQVTGMTETAFGSAYKTKKGMFRNVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN------AIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLR-HWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEGEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGMKFAKDAAGLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIEGLEEAKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSR-SGRRQLHIEGASLELSDDDTESKTSDVNETQPPQSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35580-1", "uniprot_id": "MYH10_HUMAN", "id": "P35580-1", "name": "Myosin-10", "aln": "---------------------------------------------MAQRTGLEDPE-RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS-HKGR--------------------------KDHN------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEG--FNNYRFLSNGY-IPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWK-DVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN------AIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLR-HWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSR-SGRRQLHLEGASLELSDDDTESKTSDVNETQPPQSE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7USR7-1", "uniprot_id": "A0A8N7USR7_DANRE", "id": "A0A8N7USR7-1", "name": "", "aln": "------------------------------------------MPEMAQRSGQEDPE-RYLFVDRAVVYNPTTQADWTAKKLVWVPSERHGFEAASIREERGEEVLVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS-HKGR--------------------------KDHN------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHVFYQLLAGAGEHLRSDLLLEG--FNSYRFLSNGN-IPIPGQQDKDNFQETMEAMHIMSFNHEEILSMLKVVSAVLQFGNIVFKKERNTDQASMPENTAAQKLCHLLGMNVMEFTRAILSPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWSFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVDKLVQEQGTHGKFQKPRQLKDKADFCIIHYAGRVDYKADEWLMKNMDPLNDNVATLLHQSTDKFVAELWK-DVDRIVGLDQVAGMNETAFGAAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLEPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN------AIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDIIIYFQSVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLR-HWQWWRLFTKVKPLLQVTRQEEEMQAKDEELIKVKERQVKVENELVEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLVAKKQELEEILHDLESRVEEEEERNQSLQNEKKKMQSHIQDLEEQLDEEEAARQKLQLEKVTAEAKIKKMEEDILLLEDQNSKFLKEKKLLEDRVGEMTSQLAEEEEKAKNLGKVKNKQEMMMVDLEERLKKEEKTRQELEKAKRKLDAETTDLQDQIAELQAQIDELKIQLAKKEEELQAVLARGDEEVAQKNNALKQLRELQAQLAELQEDLESEKAARNKAEKLKRDLSEELEALKTELEDTLDTTAAQQELRSKREQEVAELKKAIDDETRNHESQIQEMRQRHGTALEEISEQLEQAKRVKGNLEKNKQTLESDNKELTNEVKSLQQAKSESEHKRKKLEAQLQEVMARFSEGEKVKGELADRTHKIQTELDNVSCLLEDAEKKGIKLTKDVSSLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNNLLEQQEEEEESRKNLEKQLATLQAQLVETKKKLEDDVGALEGLEEVKRKLQKDMEVTSQKLEEKAIAFDKLEKTKNRLQQELDDLMVDLDHQRQIVSNLEKKQKKFDQMLAEEKTISARYAEERDRAEAEAREKDTKALSMARALDEALEAKEEFERLNKQLRAEMEDLISSKDDVGKNVHELEKSKRTLEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFDRDLQARDEQNEEKKRALVKQVREMEAELEDERKQRALAVAAKKKLEMDLKDVEAQIEAANKARDEAIKQLRKLQAQMKDYQRELEEARTSRDEIFTQSKENEKKLKSLEAEILQLQEDLASSERARRHAEQERDELADEISNSASGKAALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTMQVDTLNTELAGERSAAQKSENARQQLERQNKDLKSKLQELEGSVKSKFKASIAALEAKILQLEEQLEQEAKERAAANKIVRRTEKKLKEVFMQVEDERRHADQYKEQMEKANSRMKQLKRQLEEAEEEATRANASRRKLQRELDDATEASEGLSREVNTLKNRLRRGGPVSFSSSR-SGRRQLQMEG---DFSDDDADSKASDLNENQPPPAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99323-3", "uniprot_id": "MYSN_DROME", "id": "Q99323-3", "name": "Myosin heavy chain, non-muscle", "aln": "MKSAWLALKSKSALHPKSEYPVSNIHYPKAANYRQTRNYLEIAAKMSEEVDRNDPELKYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRVMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIK------------RHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDD--VKSYAFLSNGS-LPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPG---GIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKT-DFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWK-DAE-IVGMAQQA-LTDTQFG--ARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPN------VIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLR-NWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLRRTGGIGLSSSRLTGTPSSKRAGGGGGGDDSSVQDESLDGEDSAN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08964-1", "uniprot_id": "MYO1_YEAST", "id": "P08964-1", "name": "Myosin-1", "aln": "------------------------------------------------MTGGQSCS------SNMIVWIPDEKEVFVKGELMSTDINKNKFTGQ--EEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAP-----------------------VSGSS------------------IVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDR-AEQASFKN--DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHG-SATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKN--GFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISNQEVKKSARTST--FKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFN---DKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKE-----QEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIPLDS-----------ILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWER------EMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETS---TNDSEAKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKNLH--ERLSDTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYES----TMIGSK--------------NIDSNNAQSKIFS----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . .. . * : :. .*: :.: * . ..: * :: :* .: . : .*: :**..*.***:*:*** ***.***:*::.** ..********* *.:***::* :*:*. :: *:. : :.: ***::**::.**. :* : :***** **************::*:** :::. .. .. . .:* ::**:*****:****:**:*:*********:*:*: * * **:** ******* ::* ..**.:*:*****:* ..: *.. .:.* :***. :** :* :*: :.:::*:.:. ::: ::::*: :* :*.: * .:* :**:: : .. :. **:. :: *:* ** *.*:::* :::..:*..* ::*::: ***:* ::*. **: **: .:**:**:******: *****************:**: **:***.** :*.*:*.:**:* *** ****: . *::.*****. :**:**::* .**:. . : . * ::. .* : **** *:*.. ** ** ****:*: :** * : :: :::: : : . : :.: . :* . *:... ::*. .*: * .*:*:********: *:. .:: *:**************:.*:*:**** **** ***.:* *: .* . *: ** :: :*:**.::*::*::*:**::****.**:::*.*:.:::: : : **: .*: : *:*. ::: .. * :* . *:.:: ::**** :.: . :::: :::: : : *.* *: : * : *: * * : *. *: : .: *:. :.:* :. : ... : : :: . :**.*:* : *.*.: :**: :: :*.. : :: :..:. : :.* :*:. .. : .:**: * : * . :*: :* . :: : :.: * :**:.: : : : :: ** ::*.** : *:. . * : :: .:: ::: : : :. :.:.** . :: * : *:: .: *. * :: . :. . :.:: . . . . . * : . :* . : :. ..:*: ::: .:.:. . :: : *:: ::: : . ::. * : : .: .: * :. **:: *.. : : . : : .: . : * : * * : : . : : * :.* ::.:: : : . :*.: .: : ::* :* : . :. * *:*: :: : :: : :::: . *: .:. * .:: . : . :** * :.: : : ::: .:. *. :: : * :.: : : ::: ::: : *:: ::: :: ::.::: :: :: :* :: : .* *:.. : * . :: : .** :* ::*::* .* .:.* : :: * : :: :: : . : ::::.: :* *** *: : .: . : :. . : . :: *:. . : . *:: *.:*: :* ::. : . .: : :** :**: :. * . : * : :: ::*: : .:: : ::: .: : : ::.: *: : : . :* *: .. : : : :*:. *.: . : .*: .....:.: . ", "identical_positions": 426, "similar_positions": 731, "identity": "20.37%" }, { "cls_id": "homologset.agr.MGI:1930787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMC2-1", "uniprot_id": "INSM2_MOUSE", "id": "Q9JMC2-1", "name": "Insulinoma-associated protein 2", "aln": "------MPRGFLVKRTKRSGSSYRARPVEPLFPPPGPLAAQ------------------------------------------------------SSP---EEPGRGL--------LGSPCLAP---P----QDDAEWGAGGGDGPG------PSP------ARPAGPELRRAFLERCLRSPVSAESFP----SATAF-CSAAPAAVTSGEE-----------------------------------------------------------------------------------------------------------------------------------------------LVPPQVPVSVPIPVPGPAPH-----------GLQRRGKGAPVCAS--APAAVRKPKAVRRLSFADEVTTSPVLG-LKIKE---EEPGAPARALGGVRTPLGEFICQLCKHQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPTPACAAS------KPPHAPLTPPDPS-----------LATGKENGRVPRTDDQHPQAPDSSGDGQHRDSAARPGLQALVYPEAARPQAPYPEVILGRHGPGSSGASAGATSEVFVCPYCHKKFRRQAYLRKHLGTHETG----SARAPTPGFGSERTAPLTFACPLCGAHFPSADIREKHRLWHA---VREELLLPALVGAPSEA-GPGGASDGSAQQIFSCKYCPSTFFSSPGLTRHINKCHPSESRQVLLLQMPLRPGC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T92-1", "uniprot_id": "INSM2_HUMAN", "id": "Q96T92-1", "name": "Insulinoma-associated protein 2", "aln": "------MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAE--------------------------------------RATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPG------PSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTPGEQ---------------------------------------------------------------------------------------------------------------------------------------------FLLPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLG-LKIKE---EEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIAS-----FLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAG----SARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHA---VREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHINKCHPSESRQVLLLQMPLRPGC----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3B8-1", "uniprot_id": "Q9V3B8_DROME", "id": "Q9V3B8-1", "name": "", "aln": "-----MAQIQTPIPIPAPAEPIEKLSHPHSIGIQLQHKGMPHGLG-------------------------------------------------LLTTVASLPPKYRSRYLNLKTRCEIPLDLTLKLPSPLPSSDVPMAATFAEVYS------ENTS-----ASSSEVQGEVTKVEELPVKPPTPPQSPAGKRKLSRESYDDEPAKMAKKEE-----------------------------------------------------------------------------------------------------------------------------------------------EVPVETVESTPAKPVKVAESAPKTNKASTSSGKPSRNKATRKLKFDEETSSPVSGTVIRPLEDITDGSMQYSNGDIDPKYNIVEITEETKAELAAIKNVIGDYVCRLCKIKFEDAFGLARHRCACIVLLEYRCPECGKQFNCPANLASHRRWHKPRKE-------------------------------------ASKKENRNTTNQPEKQQQVEKKSEEE-----------------------------------------------LAFDCQECGKKFKRAAYLRKHQLTHQKKEKPAEKQLEMKPTTTTITGSFHFNQAVSTSSSASSSHSDEGVYVVG---SNARENYDYDNDYLSDSSSSASSAGYGRLQIVEHGLTEEESIAAAALT-NLRNCASVIQHTTMAH------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KH20-1", "uniprot_id": "A0A0B4KH20_DROME", "id": "A0A0B4KH20-1", "name": "", "aln": "MMNMNPPTHPHPHHHPHPHPHPQPQSHLQSVQHLGQHQPLPALLQGHPDTTHFVECRALPAINETFPQFGQHRPAISLLSPLDLSLRAAASVVPITPPSTPSPPRKRQRLMSEENYLWRPHMASPAAPAPVVPSSLAMQPGYFHHHQQQQHQLPHQQHHQPYATRSSLEGASFNKSHFHGTKNNFEQIPAGQSSVSSPIYVEDETIVLTEDEDETVVSSHDYNEYATDTEEVNEGDDETQQVQVSVNGDDDEEEVFVDVLGSDDDEDEATDLVATRLQAQLIETTALKRNELLYEDEELHNQAVNGLARLFDRDFPEPDVEVSGLAELQSNSGKTYTDLSGVATAEIRTTSSDNLPPPPPPPPPPATSTIPATPPLPPPPISRPHKAERRRSKLRKHMAIDEETISPVSGTIIRKLRDDEELVVR--KGDIDPAFNVVEITEEAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPKAEAAGVNPAKKRVVETGDLVQEATRSGDDASDGIYPCHICGKTFRRQAYLKKHQASHQMLDNLKNLDFFKSQQQQLTINGHQLADHVQLQHTTGQAVTSAAPYASLPRPPPGMPMYPPPSGKNYPGGQRFPGFPFQSFDQRRFYSLGEFYLSQHLERSSAFQYVQANHLRQLSNVAQTLMPPLPVKXPNPNTNVLRPVPRIAATATATGPPAAATATRQAATAAGVSSVGHAFNWVAPSTAGATATGSATATATATTAESGGNVIM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .. * * . * .. . . * : : .. . . . * : : . * * . . : . *.* . . . . :* * : * :. * . . *.. . :*:::*:**: : *.* **:***. ** :**:*.** * *.**************: . . . . .: : .. : . *:: : . . ..: : . .. . . . : .: . * . : :: . . . . ", "identical_positions": 50, "similar_positions": 91, "identity": "6.44%" }, { "cls_id": "homologset.agr.MGI:1930788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXJ4-1", "uniprot_id": "ARL10_MOUSE", "id": "Q9QXJ4-1", "name": "ADP-ribosylation factor-like protein 10", "aln": "---------------------------------MAPRPLGPLVLALGGAAAVLGSVLFILWKAYFGRGRERRWDRGEAWWGADTARLPQWDEWEPEDEEDE--PALEELEQREVLVLGLDGSGKSTFLRMLAGKPPVEGHVPTWGFNSVRLPTKNFEVDLLEIGGSQNLRFYWKEFVNEVDVLVFMVDSTDRLRLPWARQELQKLLDRDPDLPVVIVANKQDLSGAMNMVELQQELGLLASYNQREVFLLAASIAPAGSGFGEPGTVHIWKLLLQLLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AS90-1", "uniprot_id": "A0A8I6AS90_RAT", "id": "A0A8I6AS90-1", "name": "", "aln": "MHCGACSVAGSGGWARPQHHLPLQSGSVLLPGQMAPRPLGPLVLALGGAAAVLGSVLFILWKAYFGRGRERRWDGGEAWWGADTDRLPQWDEWEPEDDEDE--PALEELEQREVLVLGLDGSGKSTFLRMLAGKPPVEGHVPTWGFNSVRLPTKNFEVDLLEIGGSQNLRFYWKEFVNEVDVLVFMVDSTDRLRLPWARQELQKLLDKDPDLPVVIVANKQDLSGAMSMVELQQELGLLASDNQREVFLLAASIAPAGSGFEEPGTVRIWKLLLELLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8L6-1", "uniprot_id": "ARL10_HUMAN", "id": "Q8N8L6-1", "name": "ADP-ribosylation factor-like protein 10", "aln": "---------------------------------MAPRPLGPLVLALGGAAAVLGSVLFILWKTYFGRGRERRWDRGEAWWGAEAARLPEWDEWDPEDEEDEE-PALEELEQREVLVLGLDGAGKSTFLRVLSGKPPLEGHIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWARQELHKLLDKDPDLPVVVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAPAGPTFEEPGTVHIWKLLLELLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QEE6-1", "uniprot_id": "A0A2R8QEE6_DANRE", "id": "A0A2R8QEE6-1", "name": "", "aln": "------MLSPPFVCHPLEGNRARVFQNKPGRITCTGQQKQQLSVCRARAAPALAPGALMVVLRHFSVAFSAAMAAVGTALFIALNLFYKRRVWTPESEYFTFREEEEERSEKQVLVLGLDGAGKSSVLQGLSGAGYRRGCRPTRGFNFISLNTPACQLDFLEIGGGEDLRMYWADYLRRTNILVYVVDSSDRSRLPQAKDELHRLLKAETDLPVVVLGNKQDKPDAVSVPELREALSLSSVADQRKLFLLAAQSGSDGLSR-TCSLQKIQDLLLKLV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :. . **..*.. ::: :*. . . : : : * **.: ** .:::********:***:.*: *:* .* ** *** : * * ::*:*****.::**:** ::: ..::**::***:** *** *::**::**. :.*****::.**** . *:.: **:. *.* : :**::*****. .. * . :* .***:*: ", "identical_positions": 84, "similar_positions": 78, "identity": "30.22%" }, { "cls_id": "homologset.agr.MGI:1930790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y6V7-1", "uniprot_id": "A0A8I5Y6V7_RAT", "id": "A0A8I5Y6V7-1", "name": "UPAR/Ly6 domain-containing protein", "aln": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q09098-1", "uniprot_id": "PATE4_MOUSE", "id": "Q09098-1", "name": "Prostate and testis expressed protein 4", "aln": "MNSVTKISTLLI-------VILSFLCF----VEGLICNSCEKSRDSRCTMSQSRCVAKPGESCSTVSHFVGTKHVYSKQMCSPQCKEKQLNTGKKLIYIMCCEKNLCNSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C8F1-1", "uniprot_id": "PATE4_HUMAN", "id": "P0C8F1-1", "name": "Prostate and testis expressed protein 4", "aln": "---MRKMNTLLL-------VSLSFLYLK--EVMGLKCNTCIYTEGWKCMAGRGTCIAKENELCSTTAYFRGDKHMYSTHMCKYKCREEESSKRGLLRVTLCCDRNFCNVF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: . *.:* : .* **:* :.. .* . . * * . *** : : * :*: *.:** :*.*: . : :**.:*:** *", "identical_positions": 25, "similar_positions": 32, "identity": "22.73%" }, { "cls_id": "homologset.agr.MGI:1930791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMI7-1", "uniprot_id": "TX101_MOUSE", "id": "Q9JMI7-1", "name": "Testis-expressed protein 101", "aln": "MGACRIQYVLLIFLLIASRWTLVQNTYCQVSQTLSLEDDPGRTFNWT-SKAEQCNPGELCQETVLLIKADGTRTVVLASKSCVSQGGEAVTFIQYTAPPGLVAISYSNYCNDSLCNNKDSLASVWRVPETTATSNMSGTRHCPTCVALGSCSSAPSMPCANGTTQCYQGRLEFSGGGMDATVQVKGCTTTIGCRLMAMIDSVGPMTVKETCSYQSFLQPRKAEIGASQMPTSLWVLELLFPLLLLPLTHFP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924B5-1", "uniprot_id": "TX101_RAT", "id": "Q924B5-1", "name": "Testis-expressed protein 101", "aln": "MGACRIQYILLVFLLIASHWTLVQNIYCEVSRTLSLEDNPSGTFNWT-SKAEKCNPGEFCQETVLLIKAEGTKTAILASKSCVPQGAETMTFVQYTAPPGLVAISYSNYCNDSLCNNRNNLASILQAPEPTATSNMSGARHCPTCLALEPCSSAPSMPCANGTTQCYHGKIELSGGGMDSVVHVKGCTTAIGCRLMAKMESVGPMTVKETCSYQSFLHPRMAEIGASWMPTSLWVLELLLPALSLPLIYFP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BY14-1", "uniprot_id": "TX101_HUMAN", "id": "Q9BY14-1", "name": "Testis-expressed protein 101", "aln": "MGTPRIQHLLILLVLGASLLTSGLELYCQKGLSMTVEADPANMFNWTTEEVETCDKGALCQETILIIKAG-TETAILATKGCIPEGEEAITIVQHSSPPGLIVTSYSNYCEDSFCNDKDSLSQFWEFSETTAST-VSTTLHCPTCVALGTCFSAPSLPCPNGTTRCYQGKLEITGGGIESSVEVKGCTAMIGCRLMSGILAVGPMFVREACPHQLLTQPRKTENGATCLPIPVWGLQLLLPLLLPSFIHFS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: ***::*::::* ** * : **: . ::::* :*. **** .:.* *: * :****:*:*** *.*.:**:*.*:.:* *::*::*:::****:. ******:**:**:::.*:.. . .*.**:: :* : *****:** .* ****:**.****:**:*::*::***::: *.*****: ******: : :**** *:*:*.:* : :** :* **: :* .:* *:**:* * .: :*.", "identical_positions": 116, "similar_positions": 91, "identity": "46.22%" }, { "cls_id": "homologset.agr.MGI:1930801", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MY0-1", "uniprot_id": "SPZ1_MOUSE", "id": "Q99MY0-1", "name": "Spermatogenic leucine zipper protein 1", "aln": "MSDTDNSAEMPARCPSPNPAPGAKQEPPNSGITISLLEIGSLPTVCYHSFPPPKNSICPVEKRGRVQKFSNLLKDVKDVLKNIAGVEEKSTVG-EPFDDAYIPEDLS--ELNVRGVEKKNKIR-----------------------------------------------FKDDLFIHFDPEREQN-TMKQMLLKNQSAKNMVPKFARDLCN-AEETRGFDGMLLSVKRPRNGSLHLRGEYRKLRNNMEQLLQEADHWSKQHNELSELMRSYQECQNETQETTDKDRACLQNQPNNGLSTKQKLEEQVKKLSHDTHALHLIAALLENECQVLQQRVDILKDFHLHEAGLGHEKPLQMSCEQDK---------------------KCPKLAEADKTDAFKHTTRATEGTIR-KPKILRSPDVCFTKKARNNRFNARVAKKSLVGKRRTVSSFR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXY9-1", "uniprot_id": "SPZ1_RAT", "id": "Q6AXY9-1", "name": "Spermatogenic leucine zipper protein 1", "aln": "MADSDSSSEMPAHSPSPSPIPCAKQKPPNTGITISLLEIGSLPTFCCSSFSEPNNNMCPIRKQGKVQKFSNLLKDVKDVLKNIAGFEEKTTDG-DPFDDTYIPEDLS--ELNIRGFDKRNKLR-----------------------------------------------FKDDLFIHFDPERENT-MRQEMLFKSHSAKNMVQKFARDLCN-SEEKRGCDGVQLNAKRRRTGSVHIRGEYRKLRNNMEQLLQEADHWSKQHNELSELMRSYQECHKEIKDIVDCSRVCSQTQNNNEVPSKQKLEEQVKKLSQDTHSLHLIAALLENECQILQQRVDILRELHLHEAGPGHEKPLQTSGEQDKKCGEQDKKCGEQDKKCGEQDKKCPKLAEAEKMDGSKHTMKTTEGTITRKPKIFRCPNDCLTKKARNNRFNARVAKKSLVGKRRTISSFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXG8-1", "uniprot_id": "SPZ1_HUMAN", "id": "Q9BXG8-1", "name": "Spermatogenic leucine zipper protein 1", "aln": "MASSAKSAEMPTISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKN-RLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDK---------------------KNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALRGKMRSASSLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: .*:***: . : .* * .:*: :. ***:*:**** .. . *:. :*. : :: .***.****::**:***:**.*** * . : *::: *.**:* : *:**.:* *:: :. :* : : **:*:. ::*:::.:.::* . ***** * **.: : . :: :. :::: * *:***********:******.***:*::***:.::: .: . . . *.* ** :.:*::*********:**::*:*:*********:*****:**:::* :: * :***:* . :*** * * :**.* : *:. :: :**: * : *. : *:.*** *.:** :**:*:* ** *: **:*", "identical_positions": 156, "similar_positions": 136, "identity": "34.51%" }, { "cls_id": "homologset.agr.MGI:1930803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96BS2-1", "uniprot_id": "CHP3_HUMAN", "id": "Q96BS2-1", "name": "Calcineurin B homologous protein 3", "aln": "------------------------------------------MG---------AAHSASEEVRELEG-----------------------------------------------KTGFSSDQIEQLHRRFKQLSG--DQPTIRKENFNNVP-DLELNPIRSKIVRAFFDNRNLRKGPSGLADEINFEDFLTIMSYFRPIDTTMDEEQVELSRKEKLRFLFHMYDSDSDGRITLEEY----RNVVEELLSGNPHIEKESARSIADGAMMEAASVCMGQMEPDQVYEGITFEDFLKIWQGIDIETKMHVR-FLNMETMALCH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKL5-1", "uniprot_id": "CHP3_MOUSE", "id": "Q9JKL5-1", "name": "Calcineurin B homologous protein 3", "aln": "------------------------------------------MG---------AAHSASEEVRELEG-----------------------------------------------KTGFSSDQIEQLHRRFKQLSG--DQPTIRKENFNNVP-DLELNPIRSKIVRAFFDNRNLRKGSSGLADEINFEDFLTIMSYFRPIDTTLGEEQVELSRKEKLKFLFHMYDSDSDGRITLEEY----RNVVEELLSGNPHIEKESARSIADGAMMEAASVCVGQMEPDQVYEGITFEDFLKIWQGIDIETKMHIR-FLNMETIALCH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LJW1-1", "uniprot_id": "A0ABK0LJW1_RAT", "id": "A0ABK0LJW1-1", "name": "Calcineurin B homologous protein 3", "aln": "MRMLHTCWESHFRDPHLPPQGSSGWIKVLIDSWASENTQSIGFGPQLLLNLDVVAHTCNPRAQEVEAGGSGTLSSSLATIVKALELSPAGRKRSSPVSLSHGLVWSRETSPCHKKDGVSSDQIEQLHRRFKQLSG--DQPTIRKENFNNVP-DLELNPIRSKIVRAFFDNRNLRKGSSGLADEINFEDFLTIMSYFRPIDTTLGEEQVELSRKEKLKFLFHMYDSDSDGRITLEEY----RNVVEELLSGNPHIEKESARSIADGAMMEAASVCVGQMEPDQVYEGITFEDFLKIWQGIDIETKMHIR-FLNMETIALCH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VFQ4-1", "uniprot_id": "Q9VFQ4_DROME", "id": "Q9VFQ4-1", "name": "EF-hand domain-containing protein", "aln": "------------------------------------------MGCLCLRKFSSYPSVPQEIMNTLRMN-----------------------------------------------TALSRSQIKYLYIRFHQFSGGGKDPPSHLHKYNFYSGLLQLNPLLPTILNSMFGNKVT----------ITFVDFALFLSTFQAHSLKTSNELKNVMMDKKLRLIFNMYDNNKDGRITKYDL----VVVVHKLFSN----------LLDHVQIMRIVNTIMKEMDHTDSNQ-IMFQDFCKAFAVFDMTEMMVTW-IPEYHGRTTDDL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O77424-1", "uniprot_id": "O77424_DROME", "id": "O77424-1", "name": "EF-hand domain-containing protein", "aln": "------------------------------------------MG-----------SVGSRQLNPVQLCD------------------------------------------HQQATGLSAEQLEQLHTRFRSLDR-HQRGYLTPTDLLRIP-QLSLNPLHRQIIDGFFPSRDP-------SARIGFKQFVDTCSTILVPQFGRGSVRRRDGRVQKLQLLSKMFDTRRSGCITRSDFRQIMRSIVNLAWSQQQDQERQEGLSENRLPEVEAELQLLEHQAFGFCCDHISYGEFEKRLFSVDVDRRLSIAKWLEDDDEADAEMVLPVGSGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . :. ..* .*:: *: **:.:. . . . *.***: *: .:* .: * * :* * : . .. . :**::: :*:*. .* ** : :*. * :. : . : * : :* * .*: : : . : . ", "identical_positions": 29, "similar_positions": 56, "identity": "8.81%" }, { "cls_id": "homologset.agr.MGI:1930813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N2R0-1", "uniprot_id": "OSR2_HUMAN", "id": "Q8N2R0-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------MGSKA------------------LPAPIPLHPSLQLTNYSFLQAVNTFPA-----TVDHLQGLYGLSAVQTMHMNHWTLGYPNVHE-----------ITRSTITEMAAAQGLVDAR---------------FPFPALPFTTHLFHPKQ----------------------------GAIAHVLPALHKDRPRFDFANLAVAATQEDPPKMGDLSKLSPGLG-------------------------------------SPISGLSK---------LTPDRKPSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRHSLTHTP----------------RQDF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZD1-1", "uniprot_id": "OSR2_MOUSE", "id": "Q91ZD1-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------MGSKA------------------LPAPIPLHPSLQLTNYSFLQAVNTFPA-----AVDHLQGLYGLSAVQTMHMNHWTLGYPSVHE-----------ITRSTITEMAAAQGLVDAR---------------FPFPSLPFATHLFHPKQ----------------------------GAIAHVLPALHKDRPRFDFANLAVAATQEDPPKMGDLSKLSPGLG-------------------------------------SPISGLSK---------LNPDRKPSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRHSLTHTP----------------RQNF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY34-1", "uniprot_id": "OSR2_RAT", "id": "Q6AY34-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------MGSKA------------------LPAPIPLHPSLQLTNYSFLQAVNTFPA-----AVDHLQGLYGLSAVQTMHMNHWTLGYPNVHE-----------ITRSTITEMAAAQGLVDAR---------------FPFPALPFATHLFHPKQ----------------------------GAIAHVLPALHKDRPRFDFANLAVAATQEDPPKMGDLSKLSPGLG-------------------------------------SPISGLSK---------LTPDRKPSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQTS---SPTAASSAAKCSG--------------ETVICGGTA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q567J8-1", "uniprot_id": "OSR2_DANRE", "id": "Q567J8-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------MGSKT------------------LPAPVPLHPAPQLN-YSLLRTLNAFPV-----AVDQ---LYGLSALHTVQMNRWTVGFP-------------------------QLQGLADPR---------------FPG-ALPFPAAAAH--------------------------------LLPHKHPVHRKDRPRFDFANLAVAATQEDPP----------------------------------------------------VTGQSR---------LSPERRPARGRLPAKSKKEFICRFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHLQTS---SLSAAAAAGRCFG--------------ATATCGATV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQS7-1", "uniprot_id": "SOB_DROME", "id": "Q9VQS7-1", "name": "Protein sister of odd and bowel", "aln": "MEAVKHLSAAAAAAAAAATCSDSPAKAAASPAASSDIAEALGELKASATAAASSASKAATSKHHSNNNHKPSAAATATAAHKKSESCNSNGNKCTAATSPIGSKTSNAAMAAATATAAAATNDLAAAAAVVLSLQGTMVSSLQQAALLPANSAAAAALNLQALESYLALQRLTGKSDVFRFSNSNTGSSNSNNATTCNSSSSEADNNALPSLIDIANIELKSSCSSSSSGEPPLTAATASAAATSSPSSNNSNSTSTPTTSKCVPLPSIGTVSAAVAAAAAAAAAAASQQAALDCATAAELAAECDLPLLDGEDALSFEAGDLDSSYGSFMFNPSAFSQAETDSALHSLQATMYQDKMSVISGAAGGVGAGAVGGLEEAGSSAAAAAAQRSKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCAECGKGFCQSRTLAVHKILHMEESPHKCPVCNRSFNQRSNLKTHLLTHTDIKPYNCASCGKVFRRNCDLRRHSLTHNL----------------SAGVGGVVGGNLSDPFGSGSSSSSELGLPTGSASTAASSRDLVAVSD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQU9-1", "uniprot_id": "BOWEL_DROME", "id": "Q9VQU9-1", "name": "Protein bowel", "aln": "------------MPTESSSSEISGGGGGAIPMLRPSRMDQFMNSMAAAAAAVGGGGLPG-----AADRNGGSGGSDGGSQNGNGDSRNSSASRISAYETQLAYQQHLAG--------------LHGPPPPPPPSHHREISAFVPV--LPT-----GKVRPGSNSNYEIIAMMADKRKELALREAAA--------------AAAMLGRGPGGPGGPG---------------VPPPGVLYGPAGVPPPP------------------------------YLTGPGPSPTGAGSFPFPPGAAAAALFPPGLG---------------------------------------------------PGMHAG--------LDRRLLRAPGRAS-RPKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHKCPVCSRSFNQRSNLKTHLLTHTDHKPYECSSCGKVFRRNCDLRRHALTHAVGEVNSGDYVDVGEEDEARNLSGDEEDSLLEVDSPRQSPVHNLGESGGSGEKSESERMRLKRKAAIDHEESEEEFDDFDEEEELQDLPRVHDLPREEDDDFDPEDEEQAEVALVARFQASKAAATSQSSSSVGTKPERQGVTHCHHEGGETYTMRPHGEKHQEEPGNSGIASLPVPPSFVRYSVPPGAAGPPPAPPGAPPPTHQHPGHPHLLPPNGDPYLPILHVRRDLHHKSLNLSKAGVPPPPHTPPTIITQPESGKPPNQPLHSPHEAMPSFLGSIPMRKRILPAPTLDLMDPHHHPGLGQRTFVDSPSIYALNMSRHPPRQLLGKPPSTETSGATTEKGPPVAAPPIAPPPAPPRRTGFSIEDIMRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23803-1", "uniprot_id": "ODD_DROME", "id": "P23803-1", "name": "Protein odd-skipped", "aln": "---------------MSSTSASPISNITVDDELNLSREQDFAEEDFIVIKEERETSLSPMLTPPHTPTEEPLRRVHPAISEEAVATQLHMRHMAHYQQQQQQQQQQ-----------------QQHRLWLQMQQQQQQHQAPQQYPVYPT-----------ASADPVAVHQQLMNHWIRNAAIYQQ---------------QQQQQQHPHHHHHHG---------------HPHHPHPHPHHVRPYPAG------------------------------LHSLHAAVMGRHFGAMPTLKLGGAG----------------------------------------------------------GASG--------------VPSGATGSSRPKKQFICKYCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKCPICQRSFNQRANLKSHLQSHSEQSTKEVVVTTSPATSHSVPNQALSSPQP----------------ENLAQHLPVLDLSSSSSSSEKPKRMLGFTIDEIMSR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . *. . : : * . .: * : . . :.**:***::*.*:********************:**** ******************:***** :*************** *:: . . . : : . ", "identical_positions": 73, "similar_positions": 31, "identity": "8.1%" }, { "cls_id": "homologset.agr.MGI:1930842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WVL7-1", "uniprot_id": "ANR49_HUMAN", "id": "Q8WVL7-1", "name": "Ankyrin repeat domain-containing protein 49", "aln": "MEKEKGNDDGIPDQENSLDFSEHFNQLELLETHGHLIPTGTQSLWVGNSD-EDEEQDDKNEEWYRLQEKKMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELIAQGADVHAVTVDGWTPLHSACKWNNTRVASFLLQHDADINAQTKGLLTPLHLAAGNRDSKDTLELLLMNRYVKPGLKNNLEETAFDIARRTSIYHYLFEIVEGCTNSSPQS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VE42-1", "uniprot_id": "ANR49_MOUSE", "id": "Q8VE42-1", "name": "Ankyrin repeat domain-containing protein 49", "aln": "MEKEK-KDDEKPDLENSVDFSEQFNQLELLKTHGHLIPTGTQSLWVGNSD-EDEEQEEKNEEWYQLQEKKMEKDPSKLLLWAAEKNRLATVQRLLSEKAAEVNTRDEDEYTPLHRAAYSGHIDVVRELVAKGADVHAVTVDGWTPLHSACKWNNTKVASFLLQHDADINAQTKGLLTPLHLAAGNRDSRDTLELLLMNRYIKPELKNNSQETASDIARRTSIYHYLFEIAEGCTNSSPPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RCG8-1", "uniprot_id": "F1RCG8_DANRE", "id": "F1RCG8-1", "name": "", "aln": "-----------------MDFPEDFNQLELLDPH--VIPMGTRSNWAEEEEGEEEDEAMHTEEWHQQQELHLQDTPSELMLWAAERNRCATVERLIALDPTLVNCHDSDGYTPLHRAAYSGHHDVASALLKAGANLHARTADDWMPLHSACRWGHANVASLLLQWGSEVNAMTAGRLTPLQLAAGNAAAGKTIELLLSQRTLEAGLKNSAGETAYDIAHRTSELHRLFEIVEPCNNVY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3Y0-1", "uniprot_id": "ANR49_DROME", "id": "Q9V3Y0-1", "name": "Ankyrin repeat domain-containing protein 49", "aln": "----------------MGDYDSDDEKSQVEKLRHAKVPRG---MFVSGWDDDADELIE--------EDKNPQSSIERMILWAVNENRISEVREILKLDADTVNAKDNDGYTPLHRAAYNNFVDMAKLLLQYHANPNARTELGWTPLHSACKWNNADCAHLLLQFGADVNAESDGKQTPLHITATVSNCRNTATVLLLDRYIQPRKENNSEELASVIARRTGMSFPIFESGEEAYDCETGLID", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .. :: :: . : :* * :. : : :: :: : :. ..::***.:.** : *..:: .. ** :*.* *********... *:. *: *: :* * .* ******:*.:: * :*** .:::** : * ***:::* . .* :** :* ::. :*. * * **:**. . :** * . : ", "identical_positions": 60, "similar_positions": 74, "identity": "24.79%" }, { "cls_id": "homologset.agr.MGI:1930849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GHH3-1", "uniprot_id": "A0A8I6GHH3_RAT", "id": "A0A8I6GHH3-1", "name": "SH3 domain-binding glutamic acid-rich-like protein 1", "aln": "WSDFFFFTPSFISPLPPSRKGNSQKELFQQISRCCSRSCVLKKQFRNDVNEPEPSGVWGWDCSAGSSLKAAAGGGGALASSFHLPPPSRSNLCLAGSSVARFQPLLQLFPSPFQDSGDRPEALVSRMVIHVYIASSSGSTAIKKKQQDVLCFLEANKIGFEEKDIAAN--EENRKWMRENVPED----SRPPTGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEAQAKQQA--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJU8-1", "uniprot_id": "SH3L1_MOUSE", "id": "Q9JJU8-1", "name": "Adapter Sh3bgrl", "aln": "------------------------------------------------------------------------------------------------------------------------------MVIRVYIASSSGSTAIKKKQQDVLCFLEANKIGFEEKDIAAN--EENRKWMRENVPED----SRPSTGYPLPPQIFNECQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEAQANQQA--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75368-1", "uniprot_id": "SH3L1_HUMAN", "id": "O75368-1", "name": "Adapter SH3BGRL", "aln": "------------------------------------------------------------------------------------------------------------------------------MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAAN--EENRKWMRENVPEN----SRPATGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQA--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NFP5-1", "uniprot_id": "SH3BG_DROME", "id": "Q9NFP5-1", "name": "SH3 domain-binding glutamic acid-rich protein homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------MVLKVYVSGMSGNKEVKKRQQRVLMILDSKNIKYDTVDITEPGKESEKELMQNKSTSNGGTVSDPEPRHPLPPQLFNDDEYCGDYDAFDMANEIDTLEVFLKLAPADTTAVSTAQIELKQENGDAKKEEAETEAEDKKTEAGDGDVDVKEEAAEKAEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::**::. **.. :**:** ** :*::::* :: **: *.::: *::: ..: * * . :*****:**: :* ****** *.* ::: .** *:.. : : .* : : ", "identical_positions": 40, "similar_positions": 45, "identity": "14.08%" }, { "cls_id": "homologset.agr.MGI:1930923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0K7-1", "uniprot_id": "SLUR1_MOUSE", "id": "Q9Z0K7-1", "name": "Secreted Ly-6/uPAR-related protein 1", "aln": "MTLRWAMWLLLLAAWSMGYGEAFRCYTCEQPTAINSCKNIAQCKMEDTACKTVLETVEAAFPFNHSPMVTRSCSSSCLATDPDGIGVAHPVFCCFRDLCNSGFPGFVAGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7L8-1", "uniprot_id": "D4A7L8_RAT", "id": "D4A7L8-1", "name": "", "aln": "MTLRWAVWLLLLAAWSMGYGEAFRCYTCEQPTAINSCKNIVHCKLEDTACKTVLETVEAEFPFNHSPMVTRSCSSSCLATDPDGIGVAHPVFCCFRDLCNSGFPGLVTGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55000-1", "uniprot_id": "SLUR1_HUMAN", "id": "P55000-1", "name": "Secreted Ly-6/uPAR-related protein 1", "aln": "MASRWAVQLLLVAAWSMGCGEALKCYTCKEPMTSASCRTITRCKPEDTACMTTLVTVEAEYPFNQSPVVTRSCSSSCVATDPDSIGAAHLIFCCFRDLCNSEL-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ***: ***:****** ***::****::* : **:.*.:** ***** *.* **** :***:**:*********:*****.**.** :********** : ", "identical_positions": 70, "similar_positions": 21, "identity": "63.64%" }, { "cls_id": "homologset.agr.MGI:1930943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55043-1", "uniprot_id": "RAD_RAT", "id": "P55043-1", "name": "GTP-binding protein RAD", "aln": "----MTLNGG-SGAGGSRSAG-RERDRRRGSTPWG-PAPPLHRRSMPVDERDLQAALTPGSLAATAAGTRTQGQRLDWPEGSSDSLSSGDSGSEDGVYKVHAAGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSITVDGEEASLMVYDIWEQDGGCWLPGHCMAMGDAYVIVYSITDKGSFEKASELRVQLR-ARRQTDVPIILVGNKSDLVRSREVSVDEGRACAEVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEDNARRQAGTRRRESLGKKAKLFLGRIVARNSRKMAFLAKSKSCHDLSVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88667-1", "uniprot_id": "RAD_MOUSE", "id": "O88667-1", "name": "GTP-binding protein RAD", "aln": "----MTLNGG-SGASGSRGAGGRERDRRRGSTPWG-PAPPLHRRSMPVDERDLQAALAPGSLATTAAGTRTQGQRLDWPEGSSDSLSSGGSGSEEGVYKVLLLGAPGVGKSALARIFGGIEDGPEAEAAGHTYDRSITVDGEEASLLVYDIWEEDGGCWLPGHCMAMGDAYVIVYSITDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEDNARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55042-1", "uniprot_id": "RAD_HUMAN", "id": "P55042-1", "name": "GTP-binding protein RAD", "aln": "----MTLNGGGSGAGGSRGGG-QERERRRGSTPWG-PAPPLHRRSMPVDERDLQAALTPGALTAAAAGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNL4-1", "uniprot_id": "A0A8M9PNL4_DANRE", "id": "A0A8M9PNL4-1", "name": "GTP-binding protein", "aln": "MFGIMTLNKG---------DKLRNMDKRRGSMPFPLHLQTLHRRSMPVDDRELR-SMPAAQPSELPGLMRFNADRNSCVSDSSDSVISSGSDSDGQVYKVVLLGEHGVGKSSLARIFGGVEDSNDCEETGNTYDRSLVVDDEETSILLYDIWEQDNSQWLQDQCMRMGDAYIIVYSVTDKSSFEKASELRIQLRRARQSENIPIILVGNKSDLVRSREVSMDEGSACAVVFDCKFIETSASLHHNVRDLFEGIVRQIRLRKDSKEENARRMANCKRRESISKKAKRFLGRMVARKNKKMAFRQKSKSCHDLSVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** * :: ::**** *: .*********:*:*: ::... : .. :. * . ..*.**: *..*.*: **** * *****:*******:**. :.* :*:*****:.**.**:*:::*****:*.. ** .:** *****:****:***.*********:*** **: ::******************:*** *** ***********:*****: ****:*******:**** **** *. :****:.**** ****:***:.:**** ***********", "identical_positions": 185, "similar_positions": 67, "identity": "58.92%" }, { "cls_id": "homologset.agr.MGI:1930948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CY66-1", "uniprot_id": "GAR1_MOUSE", "id": "Q9CY66-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGGGSNNHFRGGGGGGGGSFRGGGGGGGGSFRGGGRGGFGRG-GGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGGGGG---RGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGG-FRGGRGGGG---FRGRGH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYA1-1", "uniprot_id": "GAR1_RAT", "id": "Q6AYA1-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGGGSNNHFRGG---------GGGGGGGGNFRGGGRGGFGRG-GGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGGGGGGGGRGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGG-FRGGRGGGGG--FRGRGH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY12-1", "uniprot_id": "GAR1_HUMAN", "id": "Q9NY12-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGG-SSNHFRGG----------GGGGGGGNFRGGGRGGFGRG-GGRGGFNKGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGG------RGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGGGFRGGR-GGG---FRGRGH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVE0-1", "uniprot_id": "GAR1_DANRE", "id": "Q7ZVE0-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGG------GGRGGGFNRGGGGG---RGG---------GFGGGRGGGFGGGRGGGFGGGRGGRGGFNRNQDYGPPEYVVALGEFMHPCEDEIVCKCVTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSDNMKASSFKKLQKFYIDPMKLLPLQRFLPRP-----PGEKGPP------RGGRGGGGG-RGGRGGGFRGGRGANGGGRGGF---GGRG-GGF-GGRG-----GGGGGFRGGRGGGGGRGFRGGR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVQ0-1", "uniprot_id": "GAR1_DROME", "id": "Q7KVQ0-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MGFGKPRGGG------GGGGRGFGGGGGGGGRGFGG----------GGGGRGGGGGRGGGGGFGRGGGGRGGGRGAFDTGPPERVIPLGNYVYSCQNDLVCKVDIQD--VPYFNAPIFLENKEQVGKIDEIFGTVRDYSVSIKLSDNVYANSFKPNQKLFIDPGKLLPIARFLPKP-----PQPKGAKKAFTNNRGGGGGGGG-FGGRGG----GRG--GGGRGGG---GGRGGGGFRGGAGRNGGGGGGGGFNRGRGGGGG-GGGGRGRW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28007-1", "uniprot_id": "GAR1_YEAST", "id": "P28007-1", "name": "H/ACA ribonucleoprotein complex subunit GAR1", "aln": "MSF---RGGN-----------------------RGG-------------------RGGFRGGFRGG---RTGSARSFQQGPPDTVLEMGAFLHPCEGDIVCRSINTK--IPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKCGDGVQATSFKEGDKFYIAADKLLPIERFLPKPKVVGPPKPKNKKK----RSGAPGGRGGASMGRGG----SRGGFRGGRGGSSFRGGRGGSSFRGGSR-------GGSFRGGSRGGSRGGFRGGRR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* ***. ** * *** * * * : ***: *: :* :::.*:.::**: . :******::**** *:**:***:* :.: .::* .:.: *.*** :*::* . ****: ****:* * *. *. **** .** **** **** ..* ** ** *. * **. * ", "identical_positions": 82, "similar_positions": 46, "identity": "30.26%" }, { "cls_id": "homologset.agr.MGI:1930949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BPS4-1", "uniprot_id": "GP180_MOUSE", "id": "Q8BPS4-1", "name": "Integral membrane protein GPR180", "aln": "MGGLRLLAVALTCSCWWPQGGQGKTLRGSFSSAAARDAQGQSIGHFEFHGDHALLCVRINNVAVAVGKEAKLYLFQAQEWLKLLESSPGYSCSERLARAQLTVTVTQTEHNLTVSQLPAPQTWRVFYADKFTCRDDSESPQGEEIPFEMVLLNPDAEGNPLDHFSARESGLHEFFFLLVLVYFVTACIYAQSLWQAMKKGGPMHTILKVLTTALLLQAASALANYIHLSRYSRDGLGVPLIGSLAEVFDIASQIQMLYLLLSLCMGWTIVRMKKSQSRPLQWDSTPASTGIAVFIVITQSILLLWEQFEDTSHHSAHSHRSLAGLLLIVLRICLALSLGCGLYQVITVERSALKREFYITFAKGCILWFLCQPALACIAVAFNDYQRDKLITVGVILCQAVAMVILYRLFLSHSLYWEVSSLSSVTLPLTISSAHRGRPHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V799-1", "uniprot_id": "G3V799_RAT", "id": "G3V799-1", "name": "", "aln": "MGGLRLLAVALTCSCWWPQGGQAKTLRGSFSSAAARDAQGQSIGHFEFHGDHALLCVRINNIAVAVGKEAKLYLFRAQEWLTLQESSPGYSCSERLARAQLTMTVNQTEHNLTVSQLPAPQTWRVFYADKYTCKDDTESPQEEDIPFEMVLLNPDAEGNPLDHFSARESGLHEFFFLLVLVYFVTACIYAQSLWQAMRKGGPMHTILKVLTTALLLQAASALANYIHFSRYSRDGIGLPLMGSLAEVFDIASQIQMLYLLLSLCMGWTIVRMKKSQSRPLQWDSTPASTGMAAFIVITQSVLLLWEQFEDTSHHSSHSHLSLAGVLLIILRICLALSLGCGLYQIITMERSTLKREFYITFAKGCILWFLCQPALACIAVFFNDYQRDKVITVGVILCQAVAMVILYRLFLSHSLYWEVSSLSSVTLPLTISSAHKGRPHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86V85-1", "uniprot_id": "GP180_HUMAN", "id": "Q86V85-1", "name": "Integral membrane protein GPR180", "aln": "MGGLRLLAVALTC-CWWPQGSQGKTLRGSFSSTAAQDAQGQRIGHFEFHGDHALLCVRINNIAVAVGKEAKLYLFQAQEWLKLQQSSHGYSCSEKLSKAQLTMTMNQTEHNLTVSQIPSPQTWHVFYADKYTCQDDKENSQVEDIPFEMVLLNPDAEGNPFDHFSAGESGLHEFFFLLVLVYFVIACIYAQSLWQAIKKGGPMHMILKVLTTALLLQAGSALANYIHFSSYSKDGIGVPFMGSLAEFFDIASQIQMLYLLLSLCMGWTIVRMKKSQSRPLQWDSTPASTGIAVFIVMTQSVLLLWEQFEDISHHSYHSHHNLAGILLIVLRICLALSLGCGLYQIITVERSTLKREFYITFAKGCILWFLCHPVLACISVIFSDYQRDKVITIGVILCQSVSMVILYRLFLSHSLYWEVSSLSSVTLPLTISSGHKSRPHF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************* ******.*.*********:**:***** *******************:*************:*****.* :** ******:*::****:*:.**********:*:****:******:**:**.*..* *:****************:***** ***************** ***********::****** *************.********:* **:**:*:*::*****.*******************************************:*.***:***:********* **** *** .***:***:***************:**:***:*******************:*.****:* *.******:**:******:*:*******************************.*:.****", "identical_positions": 373, "similar_positions": 55, "identity": "84.58%" }, { "cls_id": "homologset.agr.MGI:1930951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN67-1", "uniprot_id": "B0BN67_RAT", "id": "B0BN67-1", "name": "", "aln": "MAVQAALLSSHPFIPFGFGGSADGLVSAFGSLDKGCCFEDDESAVSAGALLSGSDGGDVREATRDLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGTAPPRPPSPSSTDTSAKRPPGAPGASTVATPAHCKAAPRREATQAAAAASLQSRSLAALFDSLRHIPGGAETAGGAVAASVPGLGAAS---SAGDRAGTSASSVAPGTRKVPLRARNLPPSFFTEPSRVGCCGG-GGPSGQGVSLGDLEKGAEAVEFFELLAPDFSTGNDSGVLLAADPLDPFPAGATVLRGPLELESVPFEQP-AMVGNLLYPEPWNTPSCPQSKKPPLPGVRGNMTLNEPVRLLYPTALDSPGGEDAP-ALASFTPFFPDCALPPP---HQVSYDYSAGYSRAVYPSLWRPDGVWEGASGEEGAHPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VF6-1", "uniprot_id": "F181B_MOUSE", "id": "Q80VF6-1", "name": "Protein FAM181B", "aln": "MAVQAALLSSHPFIPFGFGGSADGLVSAFGSLDKGCCFEDDESGASAGALLSGSEGGDVREATRDLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGTAPPRPASPSAADAPAKRPPGAP---TVATPAHCKAAPRREATQAAAAASLQSRSLAALFDSLRHIPGGAETAGGAEAVSVPGLGAAS---AVGDGAGTAVSSVAPGTRKVPLRARNLPPSFFTEPSRVGCGGASGVPSGQGVSLGDLEKGAEAVEFFELLAPDFGSGNDSGVLMAADPLDPFPAGATVLRGPLELESGPFEQP-AMVGNLLYPEPWNTPSCPQTKKPPVAGVRGGVTLNEPVRLLYPTALDSPGGEDAP-ALSSFTPFFPDCALPPP---HQVSYDYSAGYSRAVYPSLWRPDGVWEGASGEEGGHPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NEQ2-1", "uniprot_id": "F181B_HUMAN", "id": "A6NEQ2-1", "name": "Protein FAM181B", "aln": "MAVQAALLSTHPFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVREATRDLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGC--GPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGEEGAHRD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:***:*******.*** .***:***********:...*******::******************************************************:*** *.***::*:.**** .** ***:*** ********:**********************:*****.*** *....***.*. : ** **.: ::. **:********************.* * *** .*******************.**:.:*.::.**:**:*** *****:***** ***. ** * *:**********..*.*. :**.*:.. **.:*****: ***:* *******. *:**:*********** *************:.*.****.*******.****.* *", "identical_positions": 315, "similar_positions": 72, "identity": "73.6%" }, { "cls_id": "homologset.agr.MGI:1930957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYH3-1", "uniprot_id": "D3ZYH3_RAT", "id": "D3ZYH3-1", "name": "", "aln": "--------------MKCKPNQTRTYDPE-GFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVFVLTVTELLEDWEDSVSIGRKREWFKIEDA---IKVLQCHKP-----VHAEYLEKLKLGGSPTNGNSAAPSPPESEP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C028-1", "uniprot_id": "NUD11_MOUSE", "id": "P0C028-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 3-beta", "aln": "--------------MKCKPNQTRTYDPE-GFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVFVLTVTELLEDWEDSVSIGRKREWFKIEDA---IKVLQCHKP-----VHAEYLEKLKLGGSPTNGNSAAPSPPESEP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFP7-1", "uniprot_id": "NUD10_HUMAN", "id": "Q8NFP7-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 3-alpha", "aln": "--------------MKCKPNQTRTYDPE-GFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDA---IKVLQCHKP-----VHAEYLEKLKLGGSPTNGNSMAPSSPDSDP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96G61-1", "uniprot_id": "NUD11_HUMAN", "id": "Q96G61-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 3-beta", "aln": "--------------MKCKPNQTRTYDPE-GFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDA---IKVLQCHKP-----VHAEYLEKLKLGGSPTNGNSMAPSSPDSDP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99321-1", "uniprot_id": "DDP1_YEAST", "id": "Q99321-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase DDP1", "aln": "MGKTADNHGPVRSETAREGRENQVYSPVTGARLVAGCICLTPDKK-QVLMITSSAHKKRWIVPKGGVEKDEPNYETTAQRETWEEAGCIGKIVANLGTVEDMRPPKDWNKDIKQFENSRKDSEVAKHPPRTEFHFYELEIENLLDKFPECHKRHRKLYSYTEAKQNLIDAKRPELLEALNRSAIIKDDK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.:.*.* * : *.*:*: .::: :**:::** : .***** **:* :* : :* **.:**** **: **..*: : *. . .. :. . . : .::::* *. :*** ::* ::* . * :: *. .: ", "identical_positions": 41, "similar_positions": 58, "identity": "21.69%" }, { "cls_id": "homologset.agr.MGI:1930958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJI4-1", "uniprot_id": "D3ZJI4_RAT", "id": "D3ZJI4-1", "name": "Non-receptor tyrosine-protein kinase TNK1", "aln": "MTAFRDSIGEYLGLEATCIRLSQAIHLKQTAVLRRGLTPDMLPEASSLWLLRLLRDVQLAQFYRPILEELNVTRPEHFDFVRPEDLDNLGMGRPAQRRLTEALKRYRSGVKSKNWVYKILGGFAPEQKEIPPYSDSLPHLHEPEGGLKCLIPEGAVCRGELLGSGCFGVVHQGLWTLPGGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAPAPMPPLPVTLLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRKIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSAASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPALCSRALYSLALRCWAPHPADRPTFSNLEGLLQEAWLSEGRCVREVTEPGALRMEPGDPITIIEGS-----PDTTTWKGQNGRTLKVGNFPASAVTLADLGGSPVTHPVHRGSPARGEKYR---GGTDGDREKAVLQDLPPARNQRRKVP-------LQRMKGISKSLESVLS--------LGPRPAGGGSSPPELRRGCTRAWPQGLADLPPRPPDLPPRPPIICSS-QPIQPHRVR-----------PKREPLHNHCTGAPGSSKVTIPPGGPLSDS----------------EWQRK-----------------IVEVELSVHGVTYQECQMALRTMGGDVASAIRNLKVDQLFHLSNRSRADCRRILEHHHWDLSAASRYVLARS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ML2-1", "uniprot_id": "TNK1_MOUSE", "id": "Q99ML2-1", "name": "Non-receptor tyrosine-protein kinase TNK1", "aln": "----------------------------------------MLPEASSLWLLRLLRDVQLAQFYRPILEELNVTRPEHFDFVRPEDLDNIGMGRPAQRRLNEALKRYRSGVKSKNWVYKILGGFAPEQKEIPPRSDSPLCFHEPEGGLKCLIPEGAVRRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQEAWLSEGRCVREVTEPGALRMEPGDPITIIEGS-----LDTATWKGQNGRTLKVGNFPASAVTLADLGGSPVTHPAHRGSPAHGEKCR---GGTDGDREKATLQDLPPARSHRTKMP-------LQRMRGISKSLESVLS--------LGPRPTGGGSSPPELRR--TRAMPQRLPDLPPRPPDLPPRPPIICNSSQPTQPHKAR-----------PKRESSHNHRTGAPGASKATVPSGGPLSDP----------------EWQRK-----------------VVEVELSVHGVTYQECQVALRTTGGDVASAIRNLKVDQLFHLSNRSRADCRRILEHHQWDLSAASRYILARS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13470-1", "uniprot_id": "TNK1_HUMAN", "id": "Q13470-1", "name": "Non-receptor tyrosine-protein kinase TNK1", "aln": "----------------------------------------MLPEAGSLWLLKLLRDIQLAQFYWPILEELNVTRPEHFDFVKPEDLDGIGMGRPAQRRLSEALKRLRSGPKSKNWVYKILGGFAPEHKEPTLPSDSPRHLPEPEGGLKCLIPEGAVCRGELLGSGCFGVVHRGLWTLPSGKSVPVAVKSLRVGPEGPMGTELGDFLREVSVMMNLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAPAPTPPLLVALLCLFLRQLAGAMAYLGARGLVHRDLATRNLLLASPRTIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRHGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLE-DRARLPRPPLCSRALYSLALRCWAPHPADRPSFSHLEGLLQEAGPSEACCVRDVTEPGALRMETGDPITVIEGSSSFHSPDSTIWKGQNGRTFKVGSFPASAVTLADAGGLPATRPVHRGTPARGDQHP---GSIDGDRKKANLWDAPPARGQRRNMP-------LERMKGISRSLESVLS--------LGPRPTGGGSSPPEIRQ--ARAVPQ-------GPPGLPPRPPLSSSSPQPSQPSRERLPW--------PKRKPPHNHPMGMPGARKAAALSGGLLSDP----------------ELQRK-----------------IMEVELSVHGVTHQECQTALGATGGDVVSAIRNLKVDQLFHLSSRSRADCWRILEHYQWDLSAASRYVLARP--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NB85-1", "uniprot_id": "A0A8M1NB85_DANRE", "id": "A0A8M1NB85-1", "name": "", "aln": "-----------------------------------------MMDHDTQWLYQLLADVQLERFYLRMRDGLNVTRMEHLSYVKEADLEQIGISKPGQRRLWEAVKRYKTNMRARSWMVKATNGRAPEGNDQSNAAGSG---QGPVRALTCLIQDRELLFGDRLGSGSFGVVRKAEWHTPTGRVLPVAVKTLRSG----QVDLVSDFLQEVTSMQSLDHPNIIHLYGVVLTHPLKMVTELAPLGSLYDTLRLRHGEYPLSR--LWLFSTQIAAGMEYLESRRFIHRDLAARNVLLAAREQVKIGDFGLMRGLD-DRDHYIMTAHRRIPFAWCAPESLRTGSFSHASDVWMFGVTLWEMFTYCEEPWLGLSGRQILYRVEREGERLERPPDCPQELYAVMRKCWACNSTERPTFAQLTTMVSEAQPMEVRSVKDIAEPRRLSLQANDLVTVIDHG-----LDMCEWKGQNQRTLSVGWFPPALTAPALTAVVPASGPTLISSPVRGSLHHTGHGDTDPGRSWGTPERIDDNRRWRVPLAKEKEGSNLKKMAGMSRSLESVLGGPQDKGRGFGVNAAQRSDQRRNMQNNNVIQDPRRFSDAVVIPPPRPPPPNIKSIKPQMMMMFLDRRAANPSGWSPQTQAQPQFQPQQQGLGTSNLTRMTHLAKSSPQLDDVIEKDKEREKEQEREREREKGKERYPPLVDKEAVIAQVQAAVHGVTNEEVQKALHRCDWNPTKAEQQLKTDQLYYMNQCTREECQKVLSRYNWDLQIASRYVIRMAKERDRVLDRRGERV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: ** :** *:** :** : : ***** **:.:*: **: :*:.:*.**** **:** ::. :::.*: * .* *** :: . :.* * .*.*** : : *: ****.****::. * * *: :*****:** * :.***:**: * .*:**::::*:*:** :**:** ********: * ** * ** *:*..* ** : ::*****:**:***: . :*:.****:* *. *.:*:* . * **:********* *:** ***************: **** *:. ** *:* : ** :*. *.: **:: :*** :.::**:*::* ::.** * .*::::** * ::..* :*:*: . * ***** **:.** **.: .: * . *.: *. .:*.:*. *. * .*. . * * :. *::* *:*:******. :* ..: ... :::. . *: ** ** * : . . * * .: :. .: *: : : . *.. * :*: : :*: :***** :* * ** . : ..* ::**.***:::.. :* :* ::*.:::***. ****:: . ", "identical_positions": 250, "similar_positions": 202, "identity": "31.69%" }, { "cls_id": "homologset.agr.MGI:1930964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHX2-1", "uniprot_id": "D3ZHX2_RAT", "id": "D3ZHX2-1", "name": "THAP domain-containing protein 11", "aln": "MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQ------SPSSSTAQTAQLQPNLVSASAAVLLTLQAAVDSSQAPGTVVPAPTTSSGDDVKPIDLTVQVEFAAAEGAAAAAAASELEAATAGLEAAECTLGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELR----EKDRLLAMAVIRKKHGM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJD0-1", "uniprot_id": "THA11_MOUSE", "id": "Q9JJD0-1", "name": "THAP domain-containing protein 11", "aln": "MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQLQQQQP---------SPSSSTAQTTQLQPNLVSASAAVLLTLQAAVDSNQAPGSVVPVSTTPSGDDVKPIDLTVQVEFAAAEGAAAAAAASELEAATAGLEAAECTLGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELR----EKDRLLAMAVIRKKHGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EK4-1", "uniprot_id": "THA11_HUMAN", "id": "Q96EK4-1", "name": "THAP domain-containing protein 11", "aln": "MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASAAVLLTLQATVDSSQAPGSVQPAPITPTGEDVKPIDLTVQVEFAAAEGAAAAAAASELQAATAGLEAAECPMGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELR----EKDRLLAMAVIRKKHGM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TGZ4-1", "uniprot_id": "THA11_DANRE", "id": "Q6TGZ4-1", "name": "THAP domain-containing protein 11", "aln": "MPGFTCCVPGCYNNSHRDRDLRFYTFPKDPTQREIWLKNISRAGVSGCFSTFQPTTGHRVCSVHFPGGRKTYTIRVPTLFPLRGVNERRSRR-------GRSRK----------------------------------VSAVVPIITSVVSTANETAPLEEDEEEGDIENTTVVQIGQN--GQYIAPVDLTSSGDGSCITAVVSGGEESAVHESCSVADFALC-----------------GADHSYSLTTGTTSTELLRKLNEQRDIIALMEIKMKEMKNTIRQLRVTEARLQDELRQREQERERLICANTIIKRKL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************: *:*******. *.:****:*******************:***** *******:****:*********: * .* *: .: .. : ..:**:: . : :.. :* . *: : *:*** . : :. ...:.. * :. : : : * * *:******::***. ************:****:******.:**:**:***:*::*** *::**:. .* *:: ", "identical_positions": 137, "similar_positions": 67, "identity": "43.08%" }, { "cls_id": "homologset.agr.MGI:1931001", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHX2-1", "uniprot_id": "EDAD_MOUSE", "id": "Q8VHX2-1", "name": "Ectodysplasin-A receptor-associated adapter protein", "aln": "--------MAS-PDDP-LRSDHMAKEPVEDTDPSTLSFAMS--DKYPIQDTG--LPKAKECDTVNSNCPPNSDDQP-QGEENDFPDSTKDPLSGVSRNQPCKDRKGSCSCPSCSPRAP--TISDLLNDQDLLDTIRIKLDPCHPTVKNWRNFASKWGMPYDELCFLEQRPQ-----SPTLEFLFRNSQRTVGQLMELCRLYHRADVEKILRRWVDEEWPHRGHSDSSMHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LYE0-1", "uniprot_id": "F1LYE0_RAT", "id": "F1LYE0-1", "name": "Ectodysplasin-A receptor-associated adapter protein", "aln": "--------MAS-PDDP-LRSDHMAKEPVEDTDPSTLSFAMS--DKYPIQDTG--LPKAKECDAVTSNCPPNSDDQH-QGEENDFPDSTGDPLSGVSRNQPCKEG---CPCSSCSPRAP--TISDLLNDQDLLDVIRIKLDPCHPTVKNWRNFASKWGMPYDELCFLEQRPQ-----SPTLEFLFRNSQRTVGQLMELCRLYHRADVEKILRRWVDEEWPHRGPLDGSMHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WWZ3-1", "uniprot_id": "EDAD_HUMAN", "id": "Q8WWZ3-1", "name": "Ectodysplasin-A receptor-associated adapter protein", "aln": "MGLRTTKQMGRGTKAPGHQEDHMVKEPVEDTDPSTLSFNMS--DKYPIQDTE--LPKAEECDTITLNCPRNSDMKN-QGEENGFPDSTGDPLPEISKDNSCKEN---CTCSSCLLRAP--TISDLLNDQDLLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLEQRPQ-----SPTLEFLLRNSQRTVGQLMELCRLYHRADVEKVLRRWVDEEWPKRERGDPSRHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA70QGP6-1", "uniprot_id": "A0AA70QGP6_DANRE", "id": "A0AA70QGP6-1", "name": "Ectodysplasin-A receptor-associated adapter protein", "aln": "MCETIVMNMTS-LKAFTEPFGRVASEPVEDTDPSSFITDMSLRSNYPVQVTDSQDPVTLQLSSVPPGFLSSAVGRIRQPVEND--DSECITSASVSSDFSKELK----PCKECLFSAPPPKISDLMNDEDLLYSLRLKLDPTHCTVKNWKNFASRWGMSYDELMLLEQRKHGATYNSPTQEFLLRYNQKPVTELTELCQLYQRIDVLRLLQRWMENDWPSRWQKAH----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .::..*********:: ** .:**:* * * : : .:: . .: : * **. ** . . :* : . : .* .* ** .****:**:*** :*:**** * *****:****:***.**** :**** : *** ***:* .*:.* :* ***:**:* ** ::*:**::::** * ", "identical_positions": 86, "similar_positions": 53, "identity": "37.39%" }, { "cls_id": "homologset.agr.MGI:1931010", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNW8-1", "uniprot_id": "A0ABK0LNW8_RAT", "id": "A0ABK0LNW8-1", "name": "Lysophosphatidic acid phosphatase type 6", "aln": "-------MRVWAPVGVLASLAYCFHQRRVALAEQRAP-----VDRNLLELKMVQVVFRHGARSPLKPLPLEDQVEWNPKLLEIPPQTRFEYTVANLAGGPKPHSHYDTEYHRTVLRGGMFAGQLTKVGMQQMFALGERLRKNYVEDIPFLSPIYNPQEVFVRSTNMFRNLESTRCLLAGLFQRQKE-SVIIHTDEAISEVLYPNYQSCWSLREKTRGRKKAAISQPGILEDLEKVKAGVGIADSDNVDFFILLDNMVAEEAHSLLSSPALKRFAQLIEQRAVDMALYMLQQEDRESIQMAVGPFLYILEGNLLKAVDPSTPPSKTRKMYLYATHDVTLLPMLLALGIFDNKWPPFAVDLTVELYQHQESKEWFVRLSYNGSK------------YQEAAPTSSVHWTSS-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP40-1", "uniprot_id": "PPA6_MOUSE", "id": "Q8BP40-1", "name": "Lysophosphatidic acid phosphatase type 6", "aln": "-------MRVWVPVGVLTSLAYCFHQRRVALAEQRAPNGQRPVDRNLLELKMVQVVFRHGARSPLKPLPLEEQVEWNPKLLEIPPQTRFDYTVTNLAGGPKPHSHYDTEYRKTTLRGGVLAGQLTKVGMQQMFALGEKLRKNYVEDIPFLSPVYNPQEVFIRSTNMFRNLESTRCLLAGLFQHQKG-SAVIHTDEASSEVLYPNYQSCWVLKEKTRGRKKAAISQPGISEDLEKVKTGVGINNGDDVDFFVLLDNVAAEQVHSLLNCPALERFAQLIEQRAVDMALYVVEQEDRESIQMAVGPFLHILEGNLLKTVDPTTAPSKTRKMYLYATHDVTLLPMLLALGIFDQKWPPFAVDLTMELYQHQESKEWFVQLFYNGKEQVPRGCPDKLCPLDKFLNTMSVYSVSPEKYRTLCSKTRIVELGE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPH0-1", "uniprot_id": "PPA6_HUMAN", "id": "Q9NPH0-1", "name": "Lysophosphatidic acid phosphatase type 6", "aln": "MITGVFSMRLWTPVGVLTSLAYCLHQRRVALAELQEADGQCPVDRSLLKLKMVQVVFRHGARSPLKPLPLEEQVEWNPQLLEVPPQTQFDYTVTNLAGGPKPYSPYDSQYHETTLKGGMFAGQLTKVGMQQMFALGERLRKNYVEDIPFLSPTFNPQEVFIRSTNIFRNLESTRCLLAGLFQCQKEGPIIIHTDEADSEVLYPNYQSCWSLRQRTRGRRQTASLQPGISEDLKKVKDRMGIDSSDKVDFFILLDNVAAEQAHNLPSCPMLKRFARMIEQRAVDTSLYILPKEDRESLQMAVGPFLHILESNLLKAMDSATAPDKIRKLYLYAAHDVTFIPLLMTLGIFDHKWPPFAVDLTMELYQHLESKEWFVQLYYHGKEQVPRGCPDGLCPLDMFLNAMSVYTLSPEKYHALCSQTQVMEVGNEE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*.*****:*****:********* : . ***.**:**********************:******:***:****:*:***:********:* **::*:.*.*:**::*****************:************** :******:****:**************** ** . :****** ************ *:::****:::* **** ***:*** :** ..*.****:****:.**:.*.* ..* *:***::******* :**:: :*****:********:***.****::*.:*.*.* **:****:****::*:*::*****:**********:***** *******:* *:*.: : : **: *. ", "identical_positions": 273, "similar_positions": 81, "identity": "63.79%" }, { "cls_id": "homologset.agr.MGI:1931013", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZC8-1", "uniprot_id": "ABHD1_MOUSE", "id": "Q9QZC8-1", "name": "Protein ABHD1", "aln": "---------------MEYPYTTKMLS-----SSLSPQNGTWS--------------------DTISL------------------------------------LLALGVALYLGYYWACVPQRPRLVAG-PQFLAFLEQHCPVTVET-FYPTLWCFEGRLQTIFRVLLQSQ--PVVPYRSEVLQTPDGGQFLLD----WAEQPNSTHYPDPTTQPIVLLLPGISGSSQEPYILHLVNQALKDG---YRAVVFNNRGCRGEELLTHRAYCASNTEDLETVVKHIKRRYSQ-APLLAVGISFGGILVLNYLAQTGKAGG--LVAGLTMSACWDSFETVDSLETPLNS-LLFNQPLTAGLCRLVARNRKP---------------------IEKVLDVDFAIKARTIRQLDERYTSVAFGYKDCAAYYQAASPRTKVDAIHTPVLCLNAADDPFSPVHAFPLQAAQKSPYVALLITARGGHIGFLEGLMP--WQHCYMNRVLHQY-ARAIFQ-------------------HSVGLPDLGVLTP-EDGKS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RK23-1", "uniprot_id": "ABHD1_RAT", "id": "Q5RK23-1", "name": "Protein ABHD1", "aln": "---------------MEYLHITKMLS-----SSLSPQNGTWS--------------------DAISL------------------------------------LLALGIALYLGYYWACVPQRPRLVAG-PQFLAFLEQHCPVTVET-FYPTLWCFEGRLQTIFRVLLQSQ--PVIPYRSEVLQTPDGGQFLLD----WAEQPYSSHCPDPTTQPIVLLLPGISGSSQEPYILHLVDQALKDG---YRAVVFNNRGCRGEELLTHRAYCASNTEDLETVVKHIKHRYSR-APLLAVGISFGGILVLNYLARTGKAGG--LVAGLTMSACWDSFETVDSLETPLNS-LLFNQPLTAGLCRLVARNRKS---------------------IEKVLDVDFAIKARTIRQLDERYTSVAFGYKDCAAYYHASSPRTKVDAICTPVLCLNAADDPFSPVQALPLQAAQKSPYVALLITARGGHIGFLEGLLP--WQHCYMNRVLHQY-ARAVFQ-------------------HSVGLPGLGALTP-EDGKS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SE0-1", "uniprot_id": "ABHD1_HUMAN", "id": "Q96SE0-1", "name": "Protein ABHD1", "aln": "-----------------------MLS-----SFLSPQNGTWA--------------------DTFSL------------------------------------LLALAVALYLGYYWACVLQRPRLVAG-PQFLAFLEPHCSITTET-FYPTLWCFEGRLQSIFQVLLQSQ--PLVLYQSDILQTPDGGQLLLD----WAKQPDSSQDPDPTTQPIVLLLPGITGSSQETYVLHLVNQALRDG---YQAVVFNNRGCRGEELRTHRAFCASNTEDLETVVNHIKHRYPQ-APLLAVGISFGGILVLNHLAQARQAAG--LVAALTLSACWDSFETTRSLETPLNS-LLFNQPLTAGLCQLVERNRKV---------------------IEKVVDIDFVLQARTIRQFDERYTSVAFGYQDCVTYYKAASPRTKIDAIRIPVLYLSAADDPFSPVCALPIQAAQHSPYVALLITARGGHIGFLEGLLP--WQHWYMSRLLHQY-AKAIFQ-------------------DPEGLPDLRALLPSEDRNS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7Q7-1", "uniprot_id": "A1Z7Q7_DROME", "id": "A1Z7Q7-1", "name": "", "aln": "MLCALVRGPTTGHKLVLYRSVAELLGPVHDIRCLSAGRGVYQRQSRSQSQSQSQLQNPAHRPDLLSLSRPALSSKLSVRSLHSENDAMFYSMYAYLSNLPRLHVLGMAVVAYVVYYLIQVVKRPIIACSDGPFKQYLIRKVPTLENK-YWPTFWCVESRAQTVLASLLRSKSLPRVNYRREILSLKDGGEVALD----WMEEG------CDQSAPCILILPGLTGESQAEYIKCLVFAAQQAG---MRVVVFNNRGLGGIELKTPRLYCAANCEDLCEVVQHVRRTLPEKCKLGATGISMGGLILGNYLARKSDEARSFLSAAKIISVPWDVHKGSASIEKPVIN-SLLGRHLAGSLCRTLRNHLDIYRD----------------IYQDSDIDIQRILRCKTIKEFDALFTAKQFGYAHVNDYYSDATLHNKLDHISVPLLCLSAADDPFQPLDAIPIKAANQCTHVAIVITARGGHIGFLEGWWPS-TKDQYMGRLFTEYFTKALFDEDGEFQHTANKMHERFLAKQTVALASSSPVLFAKKIDADQLDHKVKLM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02891-1", "uniprot_id": "MCFS1_YEAST", "id": "Q02891-1", "name": "Medium-chain fatty acid ethyl ester synthase/esterase 1", "aln": "-MFRSGYYPTVTPSHWGYNGTVKHVLGEKGTKSLAFRDSKRQ----------------IPLHEFVTKHVPTLKDG---------------------------ANFRLNSLLFTGYLQTLYLSAGDFSKK---FQVFYGREIIKFSDGGVCTADWVMPEWEQTYSLNAEKASFNEKQFSNDEKATHPKGWPRLHPRTRYLSSEELEKCHSKGYSYPLVVVLHGLAGGSHEPLIRALSEDLSKVGDGKFQVVVLNARGCSRSKVTTRRIFTALHTGDVREFLNHQKALFPQ-RKIYAVGTSFGAAMLTNYLGEEGDNCP--LNAAVALSNPWDFVHTWDKLAHDWWSNHIFSRTLTQFLTRTVKVNMNELQVPENFEVSHKPTVEKPVFYTYTRENLEKAEKFTDILEFDNLFTAPSMGLPDGLTYYRKASSINRLPNIKIPTLIINATDDPVTGENVIPYKQARENPCVLLCETDLGGHLAYLDNESNS-WLTKQAAEFLGSFDELVL--------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03649-1", "uniprot_id": "MGL2_YEAST", "id": "Q03649-1", "name": "Monoacylglycerol lipase", "aln": "----MRLKELLPNFLIVHQEVPEDPIAFKSTDKRENENKEIT------------------IPELIDTKVPELADG---------------------------ATDTLYGLLVNGHLQTAYGSFRHFDNI---YKVQYKRMIIKYPHGGEGTVDFAVNGRSTKRRKVEKEYVPTSQPVFNGNLKRRYSYYSPDDP------------KLNSDDAKPMLIILHGLTGGSRESYVRAIVHEITTKYD--FEACVFNARGCCYSAITTPLLYNGGWTNDIRYCVNDLRKRFPN-RKFYMMGFSLGASIMTNYLGEESDRTK--IECAISVSNPFDLYNSAYFINSTPMGSRFYSPALGHNLLRMVRNHLSTLEE----------------NPDFKDVIEKHLKKIRTVRQFDNLLTGPMFGYKNAEEYYKNASSYKRIPGIRTPFIALHAQDDPIVGG-DLPIDQIKSNPYTLLLETSTGGHVGWFKDRSGRRWYAEPLCRFLKIFHDEITVKG-------------LKPDLENVQLPDPNCEPIATTFRAN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . : : . .. : . . . . : . : * :::* *::* *: : : .. *:* ** : * : . *: ::. : .. : * *:*. :: *:*.. . : .. :* :* . : . : . * * : : : . . . : : ::* *. :* . ** :: .:: * * : : * ***. :* . . . . : * ***:.::.. ..: : ", "identical_positions": 36, "similar_positions": 95, "identity": "6.46%" }, { "cls_id": "homologset.agr.MGI:1931026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0D3-1", "uniprot_id": "A0A8I6A0D3_RAT", "id": "A0A8I6A0D3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPLAFIVTRFLGPIQPSTKTPFWILSWRRMTGRKQSGVGGSGVASSVMSGAGLHPATRVLLPNTTLALGCALLYMLGKGGKRKFDEHEDG---------------------------------LEGKVVFPSDA------------------------------PSRVSYTLQRQTIFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEELKQEGSLRPTFTPTSQPSDSLSDSYREAPPAFTPLASPPAHPCDLGSTTPLEACLTPASLLEGD----------------------------------------------------------DDTFCTLQAVHPAAPTRLSSPALSAEKDSFSSALDEIEEL---------------CPTSTSTEAAAAAAPEGSKG-----TSSETSVQKPEGPQEGRTDDSRFMDSLPG----------------------------------NFEITTSTGFLTDLTLDDILFADIDTSMY-----------------------------DFDPCTSASGTASKMAPVSADDLLKTLAPYSNQPVAPSQPFKMDLT---------------------------------------------------------ELDHIMEVLVGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJG5-1", "uniprot_id": "SRTD2_MOUSE", "id": "Q9JJG5-1", "name": "SERTA domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGKGGKRKFDEHEDG---------------------------------LEGKIVSPSDG------------------------------PSRVSYTLQRQTIFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEELKQEGSLRPAFTPSSQPSNSLSDSYQEAPP-------PAPHPCDLGSTTPLEACLTPASLLEDDN---------------------------------------------------------DDTFCTLQAVHPAAPTRLSSAALPAEKDSFSSALDEIEEL---------------CPTSTSTEAAHTAAPEGPKG-----TSSESSVQKPEGPEEGRTDDSRFMDSLPG----------------------------------NFEITTSTGFLTDLTLDDILFADIDTSMY-----------------------------DFDPCTSASGTASKMAPVSADDLLKTLAPYSNQPVAPSQPFKMDLT---------------------------------------------------------ELDHIMEVLVGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14140-1", "uniprot_id": "SRTD2_HUMAN", "id": "Q14140-1", "name": "SERTA domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGKGGKRKFDEHEDG---------------------------------LEGKIVSPCDG------------------------------PSKVSYTLQRQTIFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEELKQEGSLRPMFTPSSQPTTEPSDSYREAPPAFSHLASPSSHPCDLGSTTPLEACLTPASLLEDD----------------------------------------------------------DDTFCTSQAMQPTAPTKLSPPALLPEKDSFSSALDEIEEL---------------CPTSTSTEAATAAT-DSVKG-----TSSEAGTQKLDGPQESRADDSKLMDSLPG----------------------------------NFEITTSTGFLTDLTLDDILFADIDTSMY-----------------------------DFDPCTSSSGTASKMAPVSADDLLKTLAPYSSQPVTPSQPFKMDLT---------------------------------------------------------ELDHIMEVLVGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JLD0-1", "uniprot_id": "B8JLD0_DANRE", "id": "B8JLD0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSKGLKRKLEDEDEPEVS------------------------------NNGSSLDESES------------------------------ESSSGYRLQRQTVLNLSLLKLHSVPGHSEPRLSRRVLISNTLRHIRDELRVEG----------------------------------------GASVRLQPSIT--------------------------------------------------------------------------------------------KDAFSSALADIEDL---------------CPTVGITALFSTADVSSSS------ESVHSDESRSVDSDLSEMRSKSLSDSTHP----------------------------------VLGHTSS--LIADFSLDDFLFTEIDNFLL-----------------------------DSKTGFGGAGIG-------------------QSALQTNQTFKLDLS---------------------------------------------------------ELDHIMEVLVGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEX7-1", "uniprot_id": "Q9VEX7_DROME", "id": "Q9VEX7-1", "name": "", "aln": "MKMWTESNVNSAMGLQATAATKRKHELTFDSKDANTTYTGNCAPPPVKANKWAISNNNYLESLEEQQQQQQSPSEPAVESNNNHIVLEASMDALKPTEPSISNGHEVTTAVAAMKSQAEVPLPPTASAAIPEDSIARLEVVTSAVPCEPWTSNGPTTPSAVAGPAASAEPVDCISKLQAVAVPSDPWGSIATRSTLATTLLSADELDDDDDDFEDDYEEEESIIPTYCPMRYHPFVPHPHPHSHQLPSHPHQQQPQQLSQQQPHPQQQQLAQQQQQHPQQQRSYAPGYGSRQPNYYSEPFPQQNCSRTGGPQHMTQSPPTPQQARGFAPPQWATAGSSPANPSSGAQQFYEPTNGGAYAPPAAPQQTIRCAENGKSYLDLGCSSGASGNAGGSPISPPPSSAPVVPFAGLPLHGLPLKRCCDGRPGGWCSANRSCYKDTRLKIRNLSMFKLSRFRQVSEQSLYRSVLICNTLKRIDREIEAEAKELHQAAQQHHQQAAAAAAAAAAAAAQAAQYHPAYQQQQQQQQSPPAPLHPHTQQQMDYAPVLNCARLANMDHYQQLSFQPQHQQQQQPSQPHSYHERLDSQPAYRGAAAGAGSFATQPSNCDTSAGASSSNTSGNSNNSSATAASSNSSLHPYDHYPFRESQSGRATPFPACPTTTAAAAAASAAAAASSGGAATTLSSNISSSPASSSTSSNTTSSTVISSSSGNTVSSNGTTPVAPTASSSNCDTSDSGYADDDSTRSINWSSVLSLSSQSALDPLNNNDLFSILPSAATPTAVPVSVPASSSSSSSGSTLAFSGSFTTVQASGGSSSSCGSSSTTATFTTLSTISSATHSLTSSYVSSISSNVSAGANTWEYGFLDMEFGLGSEFTELVPSCKLSSEDLFKSGLGGQVVTASRLHDNELEHPAHIMVGS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* :: : : *. : . . * * .: *:*::** :* * : *** * *::* *:. *. . . : .*:* :. *** : :* . . * . . . .. .. .. . .* : :: : :: :** : :: . : . . ...* . . . ...: .:: **:* .::***", "identical_positions": 35, "similar_positions": 75, "identity": "3.82%" }, { "cls_id": "homologset.agr.MGI:1931027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7P1-1", "uniprot_id": "STX12_RAT", "id": "G3V7P1-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQFQHSTNQLAKETNELLKELGS----LPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD----------LELIKERETAIQQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERASDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER00-1", "uniprot_id": "STX12_MOUSE", "id": "Q9ER00-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQLQHSTNQLAKETNELLKELGS----LPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD----------LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y82-1", "uniprot_id": "STX12_HUMAN", "id": "Q86Y82-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQLQHSTNQLAKETNELLKELGS----LPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIARARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQD----------LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMCILVLVLSVIILILGLIIWLVYKTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5F7-1", "uniprot_id": "A0ACD6B5F7_DANRE", "id": "A0ACD6B5F7-1", "name": "Syntaxin-12", "aln": "MIVCFLSIHFDFCERSSASPPHLSITVTVIMSYGMMDSS----HSQSQPRDFNNLTQTCSSNIQKITQNTGQIKSMLFQLGTRPDTPELQDR-LQQVQHYTNQLAKETNRHLKDLGT----LPQPQSPSEQRQQRIQKDRLMNDFSAALNNFQVVQRRAAERERESVARARAGSRFQVDELNQDEQLVTFEKNEGW-RMQTEEE--PVTEED----------LELIKERETNIRQLESDIMDVNQIFKDLAVMIHDQGDMIDSIEANVESAEVHVERGAEQLQHAAYYQRKSRKRMCILALVLSLVATIFAIIIWQAIR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32854-1", "uniprot_id": "PEP12_YEAST", "id": "P32854-1", "name": "Syntaxin PEP12", "aln": "--------------------------MSEDEFFGGDNEAVWNGSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKES--LEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLLFIFLIMKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : .: :*..: : :.:: .*. . ::.: * : * .:. . :::.:: : :* . :*.:.: : ..* :: * : :::*:.*.* ::::** :**: :: :: **: . :...: .: *: :..: : : *.* :**::*: * ::* .* ::*::****. ::::** ::*.****: ::. :.: .:::*::* **::: : * :** :: .: ::: ", "identical_positions": 46, "similar_positions": 122, "identity": "14.33%" }, { "cls_id": "homologset.agr.MGI:1931028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L7P8-1", "uniprot_id": "A0ABK0L7P8_RAT", "id": "A0ABK0L7P8-1", "name": "DNA 3'-5' helicase", "aln": "------MERLATVRARLQDWERAFVRLHGRRPAKEDVEAAPEETRALYREYRNLKQAVSQADDGHRVQKQ---SLAKAAEEEQEPSCWGSHLNR----AATQNTQSIPKQSPLSSIQDYGKRLKANLKNTLQG------GPTLSRKLQHQKRSLSIVP----------------TSRPPGPRTESPCP----------EQANDALPQVPVPQPR----------QGQLQKLQSSLSLRLSS-----------------------------------------------LDPGWLERCQN----------------------------------------------RVSDPLEVPGACGLDLSAK----------------------ESQPQMSGKVNVISPDILSEVSSQSP---------------------------------------------QALAQQPAQVLSQIPKSSNSKDRKRKRNEK-GEDFAQAQP----------------SSQAGPLSEGAGATAHGQGPPGEPTQVTVPQH------------------------------------RCS-----------SNQARTENAKSAAHLPMSPRPASLDRGNYVRLNMKTKCFVRVGASRGRLLRKQVWKQKWKKKQEWFGKSGPR--------ATVKDTCFRCGQFGHWASQCSQ------PGSTLTIQPKGDR---NDKHPISTLGGVAQKTGTTSCNHSGEETEPAG------------------PVLPVPHCPTP----------------------------------------------------------------VLPLYPPGPLGQVADTPAEVFQVLEQLGHHTFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYAKRSPCLTLVVSPLLSLMDDQVSDLPSCLKAACLHSGMTKKQRESVLKKVRMAHGWGGGHPSTQSLILSSLQVRAAQVHVLIVSPEALVGCGAKGPANLPPAAQLPPVAFACIDEVHCLSQWSHNFRPCYLRVCKVLREHMGVRCFLGLTATATRSTARDVAQHLGIAEELEVSG-SASIPANLHLSVSMDRDSDQALVTLLQGDRFRTLDSIIIYCARRKDTERVAALLRTCLSTVRDSKPR-------------------------GRGPETLAEAYHAGMCSQERKRVQQAFMQGHLRMVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFLHPQGEDLWELSRHVHADSTDFLAVKKLVQRVFPACSCA-----------------------------------------QRPMS--PLEEVKEHSGQQTYPVLGLACRGHKRALPVQSTVLALDMKEEAIETLLCYLELHPRHWLELLPYTYAHCHLRCPGGSAQLQALVHRCPPLAACWAKWPPK-DTSQGSSALEFDVVELADSMGWELASVRQALHQLKWDPEP-KKGAPQGTGVLVEFSELAFHLHSRGDLTDEEKDQICDFLYSRVQAREHKALAHLHQMSKAFQSVAFPSCGPCLEQSD-EGHSNRVKTLVSYYFEEE---EEEEEEETMKDTQDPKPGQTQLQDWEDQVRRDVHQLLSLRPEEKFSGRAVARIFHGIASPCYPAQVFGQDRRFWRKYLHLDFHALMHLATEELLLRGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q75NR7-1", "uniprot_id": "RECQ4_MOUSE", "id": "Q75NR7-1", "name": "ATP-dependent DNA helicase Q4", "aln": "------MERLATVRARLQEWERAFARLHGRRPAKGDVEAAPEETRALYREYRNLKQAVRQADDRHRVLEQ---SLAEAAEEAQEPSCWGPHLSR----AATQNTQSMPKQSLLSSVQDYGKRLKANLKNTTQT------GPTQSRKLQLQKRSLSTVP----------------APRPPGSKTESPCP----------DEADDALPRVPEPRPR----------LGQLQQLRSSLSRRLTS-----------------------------------------------LDPGWLERCHN----------------------------------------------RVSDLLEVPGACGLDLSAE----------------------ESQPQMSGKVNIADPDIQSEVSVQSP---------------------------------------------EAIAQQPAQVLSQSPKSINSKGRKRKWNEK-GEDFAQDQP----------------SSGAGPLSEGARATVHGQDPPGEPTQVNVPQP------------------------------------CNS-----------SNQARTEKAKGTTHLHASPRPASLDRGNYIRLNMKNKRFVRVGANRGRLLRKQVWKQKWKKKQAAFGGSGPR--------ATDKDTCFRCGQFGHWASQCSQ------PGPTLTVQEEGDR---DDKQPISTLEEVAQRTGTASCHHSGEETQPAA------------------PELQVPHCPTP----------------------------------------------------------------MSPLYPPGPLGQVAETPAEVFQALERLGYRAFRPGQERAIMRILSGISTLLVLPTGAGKSLCYQLPALLYAQRSPCLTLVVSPLLSLMDDQVSDLPSCLKAACLHSGMTKKQRESVLKKV-----------------------RAAQVHVLIVSPEALVGCGARGPGSLPQAAQLPPIAFACIDEVHCLSQWSHNFRPCYLRVCKVLREHMGVRCFLGLTATATRSTARDVAQHLGIAGEFELSG-SANIPANLHLSVSMDRDSDQALVTLLQGDRFRTLDSVIIYCTRERIQNGWLALLRTCLSMVGDSRPR-------------------------GCGPEAIAEAYHAGMSSQERRRVQQAFMRGHLRMVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFMHPQGEDLWELRRHAHADSTDFLAVKRLVQRVFPPCTCS-----------------------------------------QRPVSKSSPEEVKEHSGQQTYPVLGQACLGHERALPVQSTVQALDMTEEAIETLLCYLELHPRHWLELLPWTYAQCHLHCLGGSAQLQALAHRCPPLAACQAKWPPK-DTSQGRSSLEFGVVELADSMGWKLASVRQALHQLKWDPEP-KKGAAQGTGVLVKFSELAFHLHSRGDLTDEEKDQICDFLYNRVQAREHKALAHLHQMSKAFRSVAFPSCGPCLEQSN-EEHSNQVKTLVSYYFEEE---EEEEE--TMTDTQGPKPGQTQLQDWEDQIRRDVRQLLSLRPEERFSGRAVARIFHGIASPCYPAQVYGLDRRFWRKYLHLDFHALMHLATEELLLRGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94761-1", "uniprot_id": "RECQ4_HUMAN", "id": "O94761-1", "name": "ATP-dependent DNA helicase Q4", "aln": "------MERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTTGQAGGGLRSSE----SLPAAAEEAPEPRCWGPHLNR----AATKSPQSTPGRSRQGSVPDYGQRLKANLKGTLQA------GPALGRRPWPLGRASSKAS----------------TPKPPGTGPVPSFA----------EKVSDEPPQLPEPQPR----------PGRLQHLQASLSQRLGS-----------------------------------------------LDPGWLQRCHS----------------------------------------------EVPDFLGAPKACRPDLGSE----------------------ESQLLIPGESAVLGP----GAGSQGP---------------------------------------------EASAFQEVSIRVGSPQPSSSGGEKRRWNEEPWESPAQVQQE---------------SSQAGPPSEGAGAVAVEEDPPGEPVQAQPPQP------------------------------------CSSPSNPRYHGLSPSSQARAGKAEGTAPLHIFPRLARHDRGNYVRLNMKQKHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGAT--------VTTKESCFLNEQFDHWAAQCPR------PAS----EEDTDA---VGPEPL---------------------VPSPQ------------------PVPEVPSLDPT----------------------------------------------------------------VLPLYSLGPSGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPCLKAACIHSGMTRKQRESVLQKI-----------------------RAAQVHVLMLTPEALVGAGG-----LPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHG-PAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSG-------------------------GRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFLAVKRLVQRVFPACTCTCTR---------------------------PPSEQEGAVGGERPVPKYPPQEAEQLS-HQAAPGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCPGGPAQLQALAHRCPPLAVCLAQQLPE-DPGQGSSSVEFDMVKLVDSMGWELASVRRALCQLQWDHEP-RTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQALARLRRTFQAFHSVAFPSCGPCLEQQD-EERSTRLKDLLGRYFEEE---EGQEPG-GMEDAQGPEPGQARLQDWEDQVRCDIRQFLSLRPEEKFSSRAVARIFHGIGSPCYPAQVYGQDRRFWRKYLHLSFHALVGLATEELLQVAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2M7-1", "uniprot_id": "E7F2M7_DANRE", "id": "E7F2M7-1", "name": "ATP-dependent DNA helicase Q4", "aln": "------MDRYNDVKILLKKWEQSFFQTNNRKPNKDDIDKAPEETRQLYKEYRSLKVAK-ERNDAVKESQT---KPPESQSSTDGSGCWGSHLNRKNLPVALPKLSSDDKETLKASAQYFGMKLKNNLGGLTKE------RSFSLKKAATPRRTPQKLIKDTVDSNAAATDVESHTPKPANTCPDPSAAPVQAAKMDFEDDPSDPFPSITPSKPCSTVVGSAQKSVERVQFLRQSITRRFSS-----------------------------------------------VDSGWLARCQVFDEVEEPQKPVAGNSELAKDEKSFL-------------------QPAVGSKSGSPGTHGERVSHKNSPNEGQTFSNTLLGRKKSSLPEEEAQIDLVTSSVRNNVVLNAISGSPGTHGERVSLKSSPKLRVDD----------------ENLSEEPEFTPNTKQRKTKARKDQDSGAKTKGRKRQREADNGDDMDESEEKEGGVKKRRKTKKGETAGEDQPKKRGKKKGKVEEDDDDGSSENKKPQK------------------------------------RAMPQE---NLLGEVDEEEARAAAYAMKNTVRVRPTKNTDGNFVKINLKKKSHVKGFALRGAALRKQMYMQKFQLKGERFGGGFGRGRGRFGGFNRQGDTCYKCGGTGHWAQDCRG------KVPVNTSAEQQETPVEEEEFELPTLEEVARATGTLRSEPIVAPPSADGDSSEKEEQGAEILLNIIRPDYERPAPPPP----------------------------------------------------------------MEPLYKLKDDGKVQDVPPEVYEALRDFGYKSFRPGQEAAIMRILSGLSTLVVLSTGMGKSLCYQLPAYLYAQRSKSITLVVSPLVSLMDDQLSGLPPKLKAACIHSNMSAKQREAAIEKV-----------------------KAGQVHVLLLSPEALVGGGHSGSGCLPPADQLPPVAFACIDEAHCVSEWSHNFRPCYLRLCKVLRDRLGVRCLLGLTATATLSTALDIARHLDISDEDGIAVRSAAVPHNLQLSVSMDRDKDQALVSLLKGERFGALDSVIVYCTRREETSRIAALLRTCLQGVMLRESSKHTALQEDDDNPVGKKKKALARKKIRKPLKWIAEAYHAGLSASERRRVQNNFMCGELRVVVATVAFGMGLDKSDVRGIIHYNMPKSFESYVQEIGRAGRDGHPAHCHLFLDPEGGDLHELRRHIYADTVDYYTVKKLVQKVFPPCKCRQIQQKQQDLAQAAEVSDSELLEMELCDDSDPHQNEIPTLTHQQTPQTHTPEETEERP-QLSDECVQRFCHTHERAIPMQETVEALDITEESLETLLCYLELHPQQWVELLHPTLSVCKLQCYGGPQQLRKIAKLCAPVAVVLARRRMAGERVQSCDALEFDVVELADTMGWQLPLVKRGLRQLQWGSDTGSYGGTGRSGVHVEFSALSFYFRSYGDLTADELDAVCAFLHGRVKTQENTQLYQLKTCFRAFRSVAYRNCSLCLDDLE-ESRSQALKDLLSDYFDKRRNLELSKQCLEDEHDEEEELNKCKMRDWETQICADIRAFLCSRSDEKFSGRAVARIFHGIGSPCYPAQVYGRDRRFWRKYIQFDFNEIIRLATQEIIRTR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSE6-1", "uniprot_id": "Q9VSE6_DROME", "id": "Q9VSE6-1", "name": "ATP-dependent DNA helicase Q4", "aln": "MDDSVFKLKYQKYKLRVKVWEKDFKKKNGRVPSKYDIRDASQEIRDSYKMYYKLKTSFLEETLNDVLSEDGYDILEMSQASDFGVSMLDQDVSLNEGPQLPLDISALVGPQSSGNLEEIPQSVEGSFSNLIDLPNRQVLTNLVNRDENHVIRKFEAVEELPINQNAWGLNVSKKPPAPPQPVEASKSAPGHGKQPKAGASLKPSLSAKLFQSSRGFAKRNPRKPLSRCVSSSSSTTSLSSVPTDHHEELLDFETILIRKAQEYKEKQQAIANNPMLASEHSKESIKTLVDDGWLRRNTKENTLDEEVPFAEANNNSGTSKKTNFGLANLDLSKLKPTVKEEKVLQAKPDQMAIIQELQTDMNSSMNQKPDHLNHTPPASSQKSVAPKNKPPPSEQETDSDSDSVVAESEEEQEPQEYRQLSKRRKIVSTASGKVEVAAPVEIPNKVEPETETFAQENPDFSADEDQDATYVPENKKKDKAKRKQAAGKQKTTKPKAEPKPKTEKKAKVKAEKKPKAEKKPRNSKKAIAVEPAPDPEEDERQPLNPEDLKYVLALEAGDITSVPRINVQDLEEADATAQRYIRTFAAGPNPGLSEGSNIRVDEKRAAARKKLEERIAAGKLNENFVTINIQKKKFVRGKKSVNFSKYKKQQWRHKKRVAALSGPDMDMG-----GCDGGVLTCFQCGGVGHFAQQCKVKGDSLLPLSAQLEEDPSPFPTLAEAQEMASQGAVVAHSRNISRLPQAANAAILQGDELNESEEDDQESSGDEEVQQHPDPNWSSDEMDVDFEALDAAVEASLSQPVSQEKAASPIKTYVGHKIPEEFLKQAGLDTTASSSNRSQHGGVKPLYDLLPDGSVQDTTPEVLEALHMFGHTNFRKGQDRAIMRTLSGLSSLVTLSTGSGKSLCYQLPAYLYSRKVGAITLVISPLVSLMEDQVTGVPHFLRAHCLHTNQTAPQRMKIQQMIAN-----------------------GEIDILLVSPEAVV-AGERATGFGAILRQLPPIAFACIDEAHCVSQWSHNFRPSYLMICKVLRKNLGVRTVLGLTATATLPTRVSIINHLGISDGERGIISDIPLPDNLVLSVSKDENRDAALLQLLNSERFEPCQSIIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKK---------------------RKRVNWQAEPYHAGMPASRRRTVQKAFMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHLFLDAKGGDQSELRRHVYSNSIDRHVIRKLLQKIFVPCSCD----------------------------------------------KEASKRTALPIPLEGDGPRVHMCPGHEIGFSVEKTVEMLDIPAENISTLLCYMELDPRWCISVLSSAYVMAKVISYGGPKYLKHAAKECPPLAMAIALQIRDKTFKEDSNIIEFSVTDIAAGIGWNSGVVKYQLKDLEWVKVN---GYPKRSPITVSFYDLGFRIKVPGDFTESEIDNALDTLYTRSVKQERTQLIQLQYVAHGLAAVAYSSCGQCCNADFPQDRGEQLKAIVRNYFAND-------------YPQDLELEIEPSNVPDENIIDDVHALINMYPDNTFTGRNIARIFHGIMSPNYPAVIWGR-CKFWRAHVKVDFNRILHLANMAIIKRRT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: **: * : ..* * : *: *.:* * *: * .** : : : : . . .:. . .: .. :: .: . . : * . .. *. . . . . . . . : * : :* *** * . :. . :.: . . .. **: . . .. : : . : : *:: :*:: * .*: . *: :: : * . :*: .*:* :* . : * . : *** *.: :...** :.*. :*: ** **: *:** ***:*:*:.*.** ********** **::: .:***:***:***:**::.:* *:* *:*:. : ** : : .::.:*:::***:* * . ****:*******.**:*:*******.** :*****..:**: .******** * .: .** :: :* ** **** *.: * **: **:..** :*:*:** *. . .::***: : **.****: : .*: **. ** ..**:****:*****:::.*:*.::* .:* .****** :******* *:*****:..:* * ** ** :::: * .:::*:*::* .*.* . :.. * *: .:.:: ** **: * :.*****:**.*: :.:* : .:: . **. *: .: *.*:* * :. . :**.:..:. :**: *: * :*:* * : : *.* *.* :: **:* .* * *: * :*. * :*: :.: :**: .*. * : : :. :* :: ** : : : . : :: *:: :: .:: *:.* :******* ** *** ::* :*** :::..*: :: **. :: ", "identical_positions": 289, "similar_positions": 315, "identity": "17.08%" }, { "cls_id": "homologset.agr.MGI:1931029", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYQ1-1", "uniprot_id": "GOGA7_RAT", "id": "Q6AYQ1-1", "name": "Golgin subfamily A member 7", "aln": "MR-----------PQQAPVSG------KVFIQRDYSSGTRCQFQTKFPAELENRVDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVS------SGR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W53-1", "uniprot_id": "GOGA7_MOUSE", "id": "Q91W53-1", "name": "Golgin subfamily A member 7", "aln": "MR-----------PQQAPVSG------KVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVS------SGR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5G4-1", "uniprot_id": "GOGA7_HUMAN", "id": "Q7Z5G4-1", "name": "Golgin subfamily A member 7", "aln": "MR-----------PQQAPVSG------KVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGMS------SGR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KH14-1", "uniprot_id": "A0A0B4KH14_DROME", "id": "A0A0B4KH14-1", "name": "Ras modification protein ERF4", "aln": "MSQGGGTTPAGGNPTALQATGGGVVFSKVFIQRDYSEGTSVKFHTRLPAELEGMIERHVFEATINRLNEFYAEAEEGSCGTYCEGCIGCITAYLIYMCSETHYEKTLRKISKFVASQNERIYNTKGLQLIDPTYRGLRVIEITIFDRPGRTXLPLSHSANEFFM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .:* *********.** :*:*::*****. ::*: ** *:. **::*****: . :* ***:.*:*** *::* ******.*:*:**:: .***:** .:** * ** **********:: * : *.. ", "identical_positions": 74, "similar_positions": 37, "identity": "45.12%" }, { "cls_id": "homologset.agr.MGI:1931035", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACV0-1", "uniprot_id": "D4ACV0_RAT", "id": "D4ACV0-1", "name": "", "aln": "MATLEAAGERGLGGPRGTVERTSGAPSASATAPAERGGDGVHSRAAVGASAMFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKESALFSTELSVLHNFFSPSPKTRRQGEVVQKLTQMVGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVSDICTVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLSLSTIRHLQELVSQETLPRDSPDLLLLLRLLALGQGAWDLIDSQVFKEPKMEAELITKFLPMLMSFVVDDYTFNVDQKLPAEEK----APVTYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFSDIFLHLLTGSLALLADEFALEDFCSSLFDGFFLTASPRKDNVHRHVLRLLLHLHARVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPPQAAETPALELPLPSVPAPAAL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4Y3-3", "uniprot_id": "NELFB_MOUSE", "id": "Q8C4Y3-3", "name": "Negative elongation factor B", "aln": "MATLEAAGERGLGGPRGTVERASGAPSGSATAPAERGGDGVHSRASAGASAMFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKESALFSTELSVLHNFFSPSPKTRRQGEVVQKLTQMVGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVSDICTVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLSLSTIRHLQELVSQETLPRDSPDLLLLLRLLALGQGAWDLIDSQVFKEPKMEAELITKFLPMLMSLVVDDFTFNVDQKLPAEEK----ASVTYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFSDIFLHLLTGSLVLLADEFALEDFCSSLFDGFFLTASPRKENVHRHVLRLLLHLHARVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPTQAAETPALDLPLPSVPAPATL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WX92-2", "uniprot_id": "NELFB_HUMAN", "id": "Q8WX92-2", "name": "Negative elongation factor B", "aln": "MAELEGAGERGSGGPRGPAERASGV---SAAAPGERAGDGAPSRAVAGASAMFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKESALFSTELSVLHNFFSPSPKTRRQGEVVQRLTRMVGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVGEICTVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLALSTVRHLQELVGQETLPRDSPDLLLLLRLLALGQGAWDMIDSQVFKEPKMEVELITRFLPMLMSFLVDDYTFNVDQKLPAEEK----APVSYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFGDIFLHLLTGNLALLADEFALEDFCSSLFDGFFLTASPRKENVHRHALRLLIHLHPRVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPAQAAETPALELPLPSVPAPAPL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y113-1", "uniprot_id": "NELFB_DROME", "id": "Q9Y113-1", "name": "Negative elongation factor B", "aln": "---------------------------MIMSTPAKNNNG--------------TGLEDVNIPGQAYLREALTSCTDPLKAIESFQLENGVLLPSLRPMLPLLDLHGVRRLDFHTSLMEELRDKLIAHINEMGQK-EPRERDKKLKELLVKSFPVVRVKSLRPVVMAILRNTQHIDDKYLKILVRDRELYADTDTEVKRQIWRDNQSLFGDEVSPLLSQYIREKEHILFDHTN-LNNLFFHPTPKVRRQGEVVQKLANMIGTSVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMALHDLEVQEIISIDPCHKFTWCLDACIREKNVDIKRSRELQGFLDNIKRGQEQVLGDLSMTLCDPYAINFLATSAIKILHHLINNEGMPRDNQILILLLRMLALGLSAWVMIDSQDFKEPKLDCQVVTKFLPALMSLMVDDQCRSLHAKLPPDERESALTTIEHSGPAPDAVEAYIQESSVASILAMYYTLHTARLKDRVGVLRVLAILSACKDDRAYEDPFLHSLIALLIPMSEEFATEDFCTTLFDEFIFAGLTRENVTSRHMLKLLWYVHNKLPAGRLATLMKAMQPTTAHNEHIHKLYEILQERIG--TGAAETPVIEAPPMEFDSPLKSVPTPGPHYNVQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.:. .. :**:*:.:.. *:*:**.**:******.** *********:. **:*****. **:** *:::******: ::. :..: :..** ***::** ***.:*:: **:****.:::: :: :* **::: *:*** .*******:***:**********.*** *** **. : : ** *:**.********:*:.*:*..********************************:****:* :* ::****************: ** **:********.:*:*********** ****:*** *: *::: *:.*:.:* :***. *:****:**** .** :**** *****:: :::*:*** ***::*** .:. ***.:*: :.: :... *::. ::**. :*. :.:**.** :: ::: .:**:*. * .* *: * *** * . * :::*** ****::*** *:::. .*:: . ** *:** ::* ::...:* :* **::** .* :::**. * *:: :* * . :: ** ***:*.. ", "identical_positions": 297, "similar_positions": 182, "identity": "46.48%" }, { "cls_id": "homologset.agr.MGI:1931050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55007-4", "uniprot_id": "RGPA1_RAT", "id": "O55007-4", "name": "Ral GTPase-activating protein subunit alpha-1", "aln": "MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENADSIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQDNCSKEQLWMFSCLIPGFSAPQ-----SEYGPRTLDNLINPPLNLQ------------ETQVTIEEVTPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNK--ENQERGFSFLFSHFKKFYLPYIFPNLCKENSLYHPVLDIPQVRPKPHYVMVKKDAETNETIYCTKEPFIQARVIVIRWLVSFWLEPKPHSGPNIPGMEGEVLPKNIQRAAASLVSREESKNDTVDKADKT--AEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPIC---EAAAMRKVVKVYQEWIQQEGKPLFMQEPEETVITSSDIPCSENVTDHDISIEDGEKREEENGTNISEHVRNSTWTKNGSYQEAFH-VSEEATEQNIQAGTQAVLQVFIINSSNIFLLEPAN-----------EIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMSSQAFLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQ-APMRQRSATTTGSPGTEKARSIVRQKT---VDID-----------------------------------------------DSQILPRSTRVRHFSQSEDTGN---EVFGALHEEQ--PLPRSSSTSDILEPFTVERAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNKEDTSPKLPPLNSETGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPVDDPGVPSEWTSPASAGSSDLMSSDSHSDSFSAFQCEGRKFDNFGFGTDIGIPSSADVDSGSGHHQSTEEQEVASLTTLHLDSETSSLNQQAFSAEVATVTGSESASPVHSALGSRSQTPSPSTLNIDHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNAIMDPEIHAQVFDYLCELWQNLAKIRDNLGISADNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCS-PQFFSLGLPGATMLIMDFIIAAGRVASSAFLN--APRVEAQVLLGSLVCFPNLYCELPALHPSTPDIAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHES----------------------------HHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYAPRLQTYQPDSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQSVHSTGAENEKTEKSVLNCIYKVLHGCVYGAQSFSHPKYFPISLSDLASVDYDPFMHLESLREPEPLHSPDSERSSKLQPVTEVKTQMQQGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDN---------HYSESTELSPELFDSPNIQFFVLNNTTLVSCIQIRSEESVPGGGLAAGLVSANSNVRIIVRDLSGKYSWDSAILYGPPIVSGLPEPTSFILSMS---------------YQEKPE--------------------EPPTSNECLEDITVKDGLSLQLR------RFRETVPTWSTIREEEDVLDELLQYLGTTSPECLQRTGISLNVPAPQPVCISEKQENDVINAILKQYTEEKEFVEKHFNDLN--------------------MKASEQDEPTPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKYSILTNIGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPSESDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRSTAINASRALKSLIPLYQNLYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHFPADADH-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6GYP7-1", "uniprot_id": "RGPA1_MOUSE", "id": "Q6GYP7-1", "name": "Ral GTPase-activating protein subunit alpha-1", "aln": "MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQDNCSKEQLWMFSCLIPGFSAPQ-----SEYGPRTLDNLINPPLSLQ------------ETQVTIEEVTPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNK--ENQERGFSFLFSHFKKFYLPYIFPNICKENSLYHPVLDIPQIRPKPHYVMIKKDAETNETIYCTKEPFIQARVIVIRWLVSFWLEPKPHSGPNIPGMEGEVLPKNIQRAAASLVSREESKNDTVDKVDKS--AEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPIC---EAAAMRKVVKVYQEWIQQEEKPLFMQEPEDTAITCSDIPCSETVADHDSAIEDGEKREEENGTSTSEHVRNSSWTKNGSYQEAFH-VCEEATEQNIQAGTQAVLQVFIINSSNIFLLEPAN-----------EIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMSSQAFLQFQGKKSMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQ-APMRQRSATTTGSPGTEKARSIVRQKT---VDID-----------------------------------------------DAQILPRSTRVRHFSQSEDTGN---EVFGALHEEQ--PLPRSSSTSDILEPFTVERAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNKEDTSPKLPPLNSETGGNSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPVDDPGVPSEWTSPASAGSSDLMSSDSHSDSFSAFQCEGRKFDNFGFGTDIGIPSSADVDLGSGHHQSTEEQEVASLTTLHLDSETSSLNQQAFSAEVATVTGSESASPVHSALGSRSQTPSPSTLSRAHIEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNAIMDPEIHAQVFDYLCELWQNLAKIRDNLGISADNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCS-PQFFSLGLPGATMLIMDFIIAAGRVASSAFLN--APRVEAQVLLGSLVCFPNLYCELPALHPNIPDIAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHES----------------------------HHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIHQPQSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPVHATGAENDKTEKSVLNCIYKVLHGCVYGAQSFSNPKYFPISLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQQGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDN---------HYSESTELSPELFESPNIQFFVLNNTTLVSCIQIRSEESMPGGGLAAGLVSANSNVRIIVRDLSGKYSWDSAILYGPPIVSGLPEPTSFILSMS---------------DQEKPE--------------------EPPTSNECLEDIAVKDGLSLQLR------RFRETVPTWSTIREEEDVLDELLQYLGTTSPECLQRTGISLNVPAPQPLCISEKQENDVINAILKQYTEEKEFVEKHFNDLN--------------------MKASEQDEPTPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKYSILTNIGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNRSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRSTAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHFPADADH-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6GYQ0-1", "uniprot_id": "RGPA1_HUMAN", "id": "Q6GYQ0-1", "name": "Ral GTPase-activating protein subunit alpha-1", "aln": "MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQ-----SEHGPRTLDNLINPPLNLQ------------ETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNK--ENQERGFSFLFSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIKARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT--TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPIC---EAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEKREEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFLLEPAN-----------EIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQAFLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQ-APMRQRSATTTGSPGTEKARSIVRQKT---VDID-----------------------------------------------DAQILPRSTRVRHFSQSEETGN---EVFGALNEEQ--PLPRSSSTSDILEPFTVERAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNKEDMSQKLPPLNSDIGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMDPEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCS-PQFFSLGLPGATMLIMDFIVAAGRVASSAFLN--APRVEAQVLLGSLVCFPNLYCELPSLHPNIPDVAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHES----------------------------HHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGAQCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDN---------HYSESTELSPELFESPNIQFFVLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVSGLSEPTSFMLSLS---------------HQEKPE--------------------EPPTSNECLEDITVKDGLSLQFK------RFRETVPTWDTIRDEEDVLDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHFNDLN--------------------MKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HQV3-1", "uniprot_id": "A0AC58HQV3_DANRE", "id": "A0AC58HQV3-1", "name": "", "aln": "MFSKKPHGDVRKSTQKVLDPKKDVLTRLKHLRIVIENAESAELKHLFEQNYSHIYYVFFENFVTIEVNLKQKGHKSQREELDSILFIFEKILQLLPERIQGRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWMQALQHNALREQLWIFACLIPGFPAPQ-----SELGPRTLDNLISPPLNLQ------------EPQVTPEEISPLVPPQSGDKSQEDLTGYFLEALLKYMVNQAKSLEWKCK--ENHEKGFAFLFANFKKYYLPHIFPNFSKETSLYNPILEVPPMRPKPYYMVVKRDPETNEALYCTKENFLNARVIFIRWLVSFWLEPRSNTGTQIPGMEGENVPKNIQRAAAGLAARGEDGGPRQDSLDGGGIGEPEQSHSNTSTLTEREPSSSSLCSMDEEHLTDIEVVRRVLCSSRTNVNFITEIFRQAFLLPMC---EAAAMRKVVRVYQEWISQQDKPVFMRQPEEERFTG----------QLDSTHEQRADKDEEEDVGLTVSVRNPNWSRSKS----------SDSEYNVHAGVQATLQVFITNSSNVFLLEAAN-----------ELKSLLEEHVDMCKRVLNIYRSLVMHETMNQKTWEQILLVLLRVTECVMKRP--PSIMPHGKKSSTLSGRLAGAIFQTLIVAWIKGNLNVYISRELWDDLLSVLSSLTCWEELVTEWSLTMETLTKVLARNLYSLDLNELPLDKLSEQKQKKHKGKGGIHEGQKITVDRSFSKGWSRDPPGQAAAMRQRSATTAGSPGIEKARSIVRQKT---VALRSCSTGDSLLSSAFIRSAKSAPVLIHPVHPLLPDSVLTPLADELSDLEEPPMIQRGPRNRHCSQSEETPT--SEVFSASGELEQPPLPRSSSASDIMEPFIAERAKGALPVSDSPSHSPHFTATTTTIEFPHSSPNPQQLTDPQQLPDSQASLEVAESIYDHLCQMPGQQPPFIPDWSCPAAASANQPEGEAEEDVFSAFREFCHRENVKMEAGADLKQVQFEGDWALEWDREMEQSEKSLYECLEECDWDLSVSPQPAEDGKGAQLQRQDATDRASESEVSPQASHGPMLSNIDHKKRHSSAVHVSFRPSTESVLFHNPLDPKEAHWKTRLRRLGHFSSHSVGAKGVGEGVTCCEVVERERGSISGARRGRLGRPTLRPRGSRSRSQESGCSPSRQQQVALLGGVYKSMVHALSKPKGQAASPQRHSKSPATEAHLKDLYASVMGYFGRKTSANKDELTPKMRPMSNDAGSSNPNVSDLMDEFIQERLRARGNSGMTRRGSSPGSLEIPKDLPELLNRQNATRPADDPGVPSEWTSPASASGSDLISSDSQSDSFNAFQYDS-KFENFSFPPETCALASADQDSLSGTGQTAEEQELSSLTTLHIDSETSSLSQHGLSADTVTITGSESASPMHSLGGSRSQTPSPATLTAEHVQHKELQLDEKMHHSVLQTPDDLETSEFPTEDCSVMAGGTLTGWHADVATVMWRRMLGILGDVNYIKDPEIHAQVFDYLCELWQNLAKIRDNLGISLDNQSSPPPPDLIPPLRILTPWLFKATMLGERYKQGKLHAYKLICKIMKRRQDVSPNSDFLTHFYNIMHCGLLHQDQDIVNTIIKHCS-PRFFSIGLPGATMLILDFIVAASRVTACSSLN--APRVEAQILLGSLVCLPNLYNELPALHPTTADIIMTKFTDVKEHIIKHILTSARDEPSAPARCVALCSLGIWLCEELVHGT----------------------------QHPQIKEALNVICVTLKFSNKNVALVASDILHLLINYVDELEKFPPNTPKKIVEVLIATITYLLPATESSPHELDKRLVVSLLLCLLDWVMALPPKTLLQPVQG-ASDKEKTDKSVLSCIYKVLHGCVYGAQSFSNPSYFPIHLSDLSSPDYDPFLLLENLKEPEPLHSPDSERSSKLQPVTEVRSRIQQGLVSVAARTVISHLVNHLGHYPMSGGPATLTSQVCENQDN---------PYSESADLTPELFDAPNLQFFVLNGTTLLSYLQIRAEDGLPGGGMSAGLTTTNACVRVIVRDISGKHSWDSAVLYGPPHCITPSQTLHLYTSSNPRGEHNRDEDSLERGSQEEPEDGAFQESEEDLDEHEEAEVKEDEVEEEELEEEIEEEEVALELMAPQAKRRCREVIPNWDSLQDGEDSLDEMLQYLGYSSPECLQRTGGPLNIPAPPPNCVSEKQENDVINAILKQCAEEQDFTIHRGNELN--------------------MRAVVQQEPSPQRPQSAFYYCKLLLNILGMNSWEKRNSFHLLKKNEKLLRELKNLDSRQCRETHKIAVFYVAEGQEDKHSILSNTAGSQAYEDFVSGLGWEVNLTSHCGFMGGLQRNKSTGFTMPYFATSTVEVMFHVSTRMPPDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGVIPTEFGDVLIVIYPMKNHMYSIQIIKKPEVPFFGPLFDGAIVDGTILPTVVRATAINASRALKSLIPLYQNFYEERARYLETIVQHHLEPTTFEDYAARVFCPAPFHYLPSEAERNAVIFLPLPKPPLENIGLTKVKGKGLKRK--------VFHASCEWLMPRESAGRKSSNAGRRERLSLANVTSC----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB98-1", "uniprot_id": "Y5521_DROME", "id": "Q9VB98-1", "name": "Probable Rho GTPase-activating protein CG5521", "aln": "MFTKKSHADVKKSTAKLQDSKKDSASRLRHLRMILDNVELEESKCLFETNYSHVYFILYDTFIQAEANLKQKVHKAHREELDGSLWLLEKILCLLPELLARRWQCHSLSRIMAKLLHLGNSPKLRREGVRYFLLWYQTLGENAPGYVHAMYADLIPGLIVPQKGVVGPDTEFSASDFLTHPNMKADGGMASVFHDNAFSHPVQSSEVVALLPPSSSEKSAPPDPRDGLEVLLNSMVHTAACLRWRDNRAQKDHRAFAFLLQRFMDVFLPVFSPNFDVSCSIYNPRLDLPVMR----------------SINKKEEVMASCVVVLINWVSRFTHER-------------------------------------------------LLSHRLDCTLHIEDVDQVRLHGYQQG-----LIVRDVLYVNRENINFVHEVYRQAFLLNFTSKPQIEAIRTAIAVYRDWMTGETPPPFLLEPND----------------------DPPPPSNAGGTPRSQRLRTPSYVGAIAG---------SKDQLVVRAGRQNVLQVFVTNAANVFLVNTANLNICFPTRSRSYRSTPLEEQTEICKKVLNVYRTMVMNTEMDTRTWEQLLMVLLQVTSIVLHQN-QHTLPSGTNKSATLGGILGSAIFQTLIVTWIRAHTKVPVNVLLWEKFLNVLQSLTHREELIIEWNKTIQTLTRVFSRYTYGINLLDLPLDRVAESRAEKRRRIG---------------------------SVWQGSGSNSAANGGSAASAAISQNRQRES------------------------------------------------------LAESSSSRSEETSSQVPLPN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPRPHHQHTQSQGGTGHGTRPIPLTPMLSRSYSEGSLASAARSSRIRRRRAATPKPKALQPSQLAENRINPQDLRRAMSLDSLARKGDAEETDSYQE-----------------------------------------------------------------GDNESGAGSRSPSPTASSG-----------IEGGSIKDAQLQIDASLDDANSGSYGSGSNSGSISGRRCIILGGSAEGWHPDSTSIMWKRMLGALGDVNRIPKADLHAQVFMHLLEMTQNLIKIKQNQGISTDNQNTQPMPPLVPPIGIVAPWCYGSLSLDRSFKKGKLWALQLLCSLAIQG---AVNMQQLPLFYHALHQLLTGEDRDLIYAILKHLEGPRLLSLLLPGHTLLLLDLVHASAILLTSLEVSRSTPRAEVAALLGSLLCYPSSLLTRSVLQPTPQKFELMECSDLQDHILNIVLRCARREPSAKARCIALSQLGQWLLMRLSQPLPASNSGRANLFQQAVPHHKDVHPKASSVYNPRIKEVLQVLLQALQFKHHTIAIVAVDSLKLCAERGRQLAAIERVPQLIITAICKALEIQSVTKPKDS----DKVVLTSLMLCLGEFCMAIPAPIMLTPFNE-------QGDTLVLQVLRVLLQVASGAPRHER-------VKLTADDDFDMHIAHDDLQGDGRLPEATYQTSETIQKCITA--------IKLCAKAVSMHLVTHIGHFPMGIGASRLSSMVEEQDDIGNAAYGGQVETRRDSVELPSVVSAQNMQLFMLNSGLVASFIELP-TLKLPGGGITAGLVTADKQVRVLMRDLNGKACWDASILYSEPRNAEEPPKTTPKIQHS------------------------------------------QPLDSMATSMVTHTPSPRHTLR-----HRPAGVLPLAKDMAPDLDQLDDMLAYIGHTSPECVAPTVSQLNAPTASP--LSGNQEAQAISVILNQRLLEQEFVTHSTQAPSPALRHASSNSSLQQPDQRSLHSTTASFDSLPTRTEMPFQYCRLLFSHLGLAGWERRSRTHLLQRSEKLMRELRNVDLQKCRETHKMAVIYVAAGQEDKGSILRNTSGSSTYEMFVSALGWEIDLETHNGFLGGLPR-QGCGATAPYYATPFLEVVYHVATRMPSDSSEAMLLKTRHLGNDEVHIVWSEHNRDYRRDILPTEFCDVLIVVYPLRNGLFRVTVNRKPEVPWFGPLANESVVSGACLATLIRATAINASRTKRAALPLYQQFYEERNRSLDSVSSRYKESTTFEDFASRIYNPMPLSTLGTLRESNASSSAAPLASALLDHNRASVKGWVQASIDSGPIMGIAPSASAGSTAAMEAATGMSSASPRGPRKLGAPFKSVTKKHSLQHIAVGGGAGAGGDTPPESPTLPQRRFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**.*.**:*** *: *.*** :**:***::::*.: : * :*: ::**:*:::::.*: *..**** **::*****. *:::**** **** : *** **:. *: **** *** *:****** **** *:* .*. ::: ****: .** .: : * * * :. : . * .*: .*:**.*.:*. . **.**: :* . .*.*: : ::..:.*:**: .* . :** : **: . *:*:* *::* :* :: .:* : .. *:.*.*: * * ** .** .: .. * . :: :** *: .* *:**: *::****** : : *:*..: **::*: : * *: :*:: : .: .. : :*...: : . : ::** * .****: *::*:**::.** .. *:*:.::**::**:** :*:: *: :****:*:***:**. *:: : :*. **.* *...:******:**:.: :* :. **:.:*.**.*** *** **. *::***:*::* *.::* :****:::*.: :*:: * .: * *.:.:.: * . * : : *: : ... * . *.:. . : ..: * . . . : :: . . : :* . . . : * . : .: : : * .* .:** .: .: : :**.*.** * : ::. :**:* .:..: : .. . * : .:: **: ***.* :::**:**** ***** * ..::***** :* *: *** **::* *** ** .: . * *:**: *::** : : * :*:*** * :*:*. : : * : *. **: :* * *:*:: :*:** . *:::*: *** *:*::*:: *:. : :. :. :**.*. *****:* *. . *:*. .. : : :*::: *:: :* .** ***. ***:**..** *: .* : :*:***.*:*: :*:*.::.:* ** : *:: . .* . * : * :. .: * ** ::.**:*** :: **:* :* ..: .::: : :** . ** ... :. :. *:* .: :.*: * .. : *..:* . :.:.*::* ***.*:**:**. *.: *:* * *:.* ..: *.:..: *:*:*:**. : * ::: :****::***.::: **:::**:.** .**:::**. * . . . .. . : * .:* . : * **::* *:* :****: * ** *:. * :* :** :.*..**:* *::*. : : . : . :. * :.: .* **:**:. **: .*::* ***::.***:***:*:* ::******:**:*** ***** *** * .**.:** **:.****::* .* **:*** : :. * * **:**. :**::**:****.:*.::: * ***************.*****.::**** *****:**::* :: : : :*****:**** : ::*.* *. ::*:*******: :: :****::**** * *::: .:: *.*****:*:::: * * : : : ", "identical_positions": 595, "similar_positions": 603, "identity": "22.18%" }, { "cls_id": "homologset.agr.MGI:1931051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTF3-1", "uniprot_id": "E9PTF3_RAT", "id": "E9PTF3-1", "name": "", "aln": "---------MAVSRCPRRRLAELTVDEFLASGFESESESELEDIKEPAAKEKKGQRAVANREQRGAHTSPS----LHKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDTSVEEEEQ----FHSLPDRLEETSETEE-----------DGGGDSDTLPRGLQRKKNE--PVPVTLAMVERWKQGA-MHHLTPKLFHEVVQAFRAAVATT-----QGDQEAPETCRFQVTDSAVFNALVTFCIRDLCGCLQKLLFAKTV-KDSSRMLLPSSSPLWGKLRVDVKTYLSAVVQLVASLAEATVSAAVLQHISSLVPYYLTFPKQCRMLVKRMIVLWSTG-EESLRVLAFLVLIKVCRHKKESFLGPILKQMYIMYVRNCKFTSPSTLPLISFMQRTLTELLALDPSVSYQHAFLYIRQLAVHLRNAMTTGKK--------ETYQSVYNWQYVHCLYLWCRVLSALGSSEV-------LQPLLYPLSQIIIGCIKLLPTARFYPLRMHCVRALTLLSQTVGTFIPVLPFILEIFQQVDFNKRPGRMS-SKPINFSVILKLSSTNLQEKAYRDGLLEQLYDLIMEYLHGQAHSIAFPELVLPTVLQLKSFLRECKVANYCRQVRQLLEKVQENAEHIRSLRQR--VTFSVSDQLAVDAWEKKVREEGTPLTRYYSHWKKLRDREIQLEISGKERLEDLNFPEIKRRKVEDRKDEDRKELKDLFELDSSEGEDSTDFFERGVPG-LLESHRGMKEGGQEEEHKEDSDSSSEDGDTDTGVDLS-------ELWQLAQGPQDELEDLQLSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV70-1", "uniprot_id": "NOC2L_MOUSE", "id": "Q9WV70-1", "name": "Nucleolar complex protein 2 homolog", "aln": "---------MAASRAPRRRLEDLSVDEFLASGFESGSESELEG----AAEERRARGAAWNRERRGARTSPGPAGRLRKGRASEHKDQLSRLKDRDPEFYKFLQENDRSLLDFSDSDSSAEEEEP----FHSLPDTLEEASETEE-----------DGGEDSDALPRGLRSKKNE--PVPVTLAMVERWRQGS-RHHLTPRLFHEVVQAFRAAVATT-----QGEQEAAETCRFQVADSAVFNALVTFCIRDLCGCLQKLLFGKTP-KDSNRLLLPSSSPLWGKLRVDVKSYLSAVVQLAACLAEATVSAAVLQHISSLVPYFLTFPKQCRMLLKRMVVLWSTG-EESLRVLAFLVLIRVCRHKKEAFLGPILKQMYIMYVRNCKFTSPSTLPLISFMQRTLTEMLALDPSVSYQHAFLYIRQLAVHLRNAMTTGKK--------ETHQSVYNWQYVHCLYLWCRVLSTLGSSEI-------LQPLLYPLSQIIIGCIKLLPTARFYPLRMHCVRALTLLSQTIGTFIPVLPFILEIFQQVDFNRRPGRMS-SKPINFSVILKLSSTNLQEKAYRDGLLEQLCDLILEYLHSQAHSIAFPELVLPTVLQLKSFLRECKVANYCRQVRQLLEKVQENARHIESLRQS--ATFSVSDRTAVDAWEKQVREEGTPLTRYYGHWKKLRDREIQLEISGKERLEDLNFPEIKRRKVEDRKDEDRKELKDLFELDSSEGEDSTDFFERGVPR-LPEAHQGLKED-QEEEDKEEGDSDSEDGDTDTGVDLS-------ELWQLAQGAQDELEDLQLSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3T9-1", "uniprot_id": "NOC2L_HUMAN", "id": "Q9Y3T9-1", "name": "Nucleolar complex protein 2 homolog", "aln": "---------MAAAGSRKRRLAELTVDEFLASGFDSESESESEN--SPQAETREAREAARSPDKPGGSPSAS----RRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGP----FHSLPDVLEEASEEEDGA---------EEGEDGDRVPRGLKGKKN---SVPVTVAMVERWKQAA-KQRLTPKLFHEVVQAFRAAVATT-----RGDQESAEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVA-KDSSRMLQPSSSPLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVIVWSTG-EESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPGALPFISFMQWTLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKK--------ETYQSVYNWQYVHCLFLWCRVLSTAGPSEA-------LQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFILEMFQQVDFNRKPGRMS-SKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHCIGFPELVLPVVLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQR--VSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILR-PLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPG-----ELQQLAQGPEDELEDLQLSEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFC4-1", "uniprot_id": "F1QFC4_DANRE", "id": "F1QFC4-1", "name": "", "aln": "-----------MAGKNKRKLEDLSVDEFMLSGFDSDEEDDCED---EEPSPKKGKSKTPALQKTSVK---------KHGKASEHKDQLSALKTKDPEFYKFLEQNDQELLNFDDTDSDEEEEDEEEQMYHKLPSQLEEDDDDDDEE---------EEEDEEDSKKKDVKKQKSSKEGTKVTEAMIENWKTAL-KKEPTPTLIRDITQAFKAAVATT-----KGDSD--ELCRYVISDSAVFNSLVLFCIRDMHAALQKMLKLKTPDKDTKKLVLPFSSTRWQKNQIDIKMYLAGVVQLLSSLTQATVIAAVLRHANQMVPYYLCLPKQCRQFLKSLIKHWSTG-EETVRVLAFLALNKICRHKPDAHLSAVLKQMYIAYVQNCKFTSPNTLPMINFMQRTLAEMYSLDTQVSYQHTFLYIRQLAIHLRNAMNLKKK--------ETYQSVYNWQYVHCLYLWCRVLSTIYPSEV-------LEPLIYPLCQVIIGCIKLVPISRYYPLRLHCVRAIILLSGNTKTFVPALPFLLEILQQEDFNKKPGRMS-VKPINFAVILKLSKFNLQEKAYKDGLVEQLYDLILECFHTQACSIGFPELALPTIIQLKAFLKECKVANYCKQMRQLLEKIQENCSHITGRRQK--AAFGVADVTAVAAWEKLVAEEGTPLTKYYSQWKKLREKEIQLEISGKERMEDLNLPEIKRKKAEEKK-ADKKEFKGLFESDSDDDDDDNLFQSKEEKDDSDEDDEGLEDLTDLSDEDNEDDSDGDQKQPSSSKGKAPKKMLSTELKQVAEGDEDMVEDLELSDQD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIF0-1", "uniprot_id": "NOC2L_DROME", "id": "Q9VIF0-1", "name": "Nucleolar complex protein 2", "aln": "------------MKLATKKIKTLGKSKPDLSKKKPAKDAIRKTKPQTTSETKVTPRNPKQKVAEPVKNGKT----TKKGFKKSHKEELEGLKDIDPEFYDFLKNNDKKLLDFNLLDTDDDDDEEGDEEDKEDTVTKESKDDEDDEEKYHKPSKDLEVASDESDFEVDEEDDAAAGGIQKITLNLLHQWEQQLGQANISIDIVRKVIQAFNSALASISADGADGGENKHNAAAFKVVGAAAFNGVIQLCVIHLQPAIIRLLGVRPN-----SSLPLHKHKKWVKVRGCLRYYLTDLIRLVEQVSSPNILGVLLKHLHQMAGMVVPFSALGKTILKRLVVLWSTG-DETVRVLAFLCILKITRKQQATMLNHVLKAMYLAYVRNSKFVSPNTLPGINFMRRSLVEMFALDLNVSYQHVFLYIRQLAIHLRNAVILKKK--------DSFQAVYNWQFINSLRLWADLLGASANKPQ-------LQPLIYPLVTIATGVIRLIPTAQYFPLRFHCLQTLISLAKETNTYVPVLPLIVEVLKSNTFNRKHSAVS-MKPVQFTCVLRLNKGQLAENGFRDEVIEQVCGLLLEYLAHESTSLAFSDLVVPTVMAIKTYLKECRNANYARKLKQLLEKIQESARFIEQQRGKSSVTFDIKDAQAVAAWEQQLRLKRTPLDVYYASWLKTHETKKRRQAAHTDEIN-ADYDVPKLKKLPVKTGVPVRNENGEVELFPSDSEDE------GDDGLHLGSDDDDDEDVQEEEEVEVEHPKAKKAKKEKPEKQKPRPATVEDDYDEAGGAVDIVKDLDLNEW-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39744-1", "uniprot_id": "NOC2_YEAST", "id": "P39744-1", "name": "Nucleolar complex protein 2", "aln": "MGKVSKSTKKFQSKHLKHTLDQRRKEKIQKKRIQGRRGNKTDQEKADAAGTREQQQLKKSAKEEVFKDMSVETFFEKGIEIPKENKKLKKKTTKEQSDEDSSSSEEEEDMGQSMAKLAEKDPEFYKYLEENDKDLLDFAGTNPLDG--IDSQDEGEDAERNSNIEEKSEQMELEKEKIELSLKLVRKWKKQL-HDSPSLKLLRNIISAFKVAVNLN-------KEENIEDYKYAITDEKAFHELMFMVLKDVPQAIQKMAPYKIV----KGARTLPNGGNVSRVSSIVKSHAGSLLILLNDITNTETAALVLHSVNELMPYLLSYRRILKELIKSIVGVWSTTRELETQIASFAFLINTTKEFKKSMLETTLKTTYSTFIKSCRKTNMRSMPLINFQKNSAAELFGIDEVLGYQVGFEYIRQLAIHLRNTMNATTKKSSKINSAEAYKIVYNWQFCHSLDFWSRVLSFACQPEKENGSESPLRQLIYPLVQVTLGVIRLIPTPQFFPLRFYLIKSLIRLSQNSGVFIPIYPLLSEILTSTAFTKAPKKSPNLAAFDFEHNIKCTQAYLNTKIYQEGLSEQFVDLLGDYFALYCKNIAFPELVTPVIISLRRYIKTSTNVKLNKRLSTVVEKLNQNSTFIQEKRSD--VEFGPTNKSEVSRFLNDVAWNKTPLGSYVAVQREVKEEKARLMR------------------------------------------------------------ESMEEQDKERETEEAKLLNSLESDDDN-------------------------EDVEMSDA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: . . . . : : ..:.:*. . : . . ..::.. :. . . .: .. : . : . . :: ::..*. : :.:.: .**. *: .: : : : . .*: :: : : .: .: :: : . : :: : : * ::.. . :*: : : : ::* :: *** : :: :* : . :. : * ** * :::..: .. ::* *.* : : .*: .:: :.** * ******:****:: .* ::.: *****: :.* :*. :*. *. *:*** : * *:*:* .:::***:: :::: *: .::* *:: *:: . *.: . ..:* :: .. * : ::: : **. .* : : . :.*.:*. *.:: :: ::: . .: ::: :: *:::.. .* * . *. : * : : : *** * . : :: : : . .: . : : .. . . . :*:::.: ", "identical_positions": 78, "similar_positions": 238, "identity": "9.61%" }, { "cls_id": "homologset.agr.MGI:1931053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI50-1", "uniprot_id": "MARH7_RAT", "id": "Q5XI50-1", "name": "E3 ubiquitin-protein ligase MARCHF7", "aln": "MESKPSRIPRRISVQPSGSLSARMVSGN----------RGTSLNDSYHSRDSSFRLDSEYQ-----------------------SASASASASPYQSTWYSESEITQGARSRSQNQQR-------------DHDSKRPKLSCTNCTSTSAGRNIGSGLNTLS--DSSWRPGQVPRS-----SSMVLGSFGTDLMRERRDLERRRDSSISSLMDYSHRSGDFTAPAYVQERVPSSYSQGARPKENAANTLQLN-SSTNHQLPSEHQTVPSSRDSS--RSSFRSHFSPRQ---SESFRNSS-HPAFSYLSSRNETPTISSSERA--------GSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLSSEN--YISPRTLTS-QSRNNGASSS-EVNDGRASEASQGFRFLRRRWGLSSLSQNHSSEPDAENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRISPSDVPPRSHLFR---RESNEVVHLEAQGDSLGAAASRPQASGASG-NASASGSTPDLPQGGRNTGIAGILPGSLFRFAVPPALGSNLTDNVTITVDIIPSGWSSADGKSEKAKSAPSRDPEKLQKIKESLLLEDSDEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQECMKKWLQAKINSGSSLEAVTTCELCKEKLQLNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTIEPSTRVRFINLARTLQAHMEDLETSEDEF------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV66-1", "uniprot_id": "MARH7_MOUSE", "id": "Q9WV66-1", "name": "E3 ubiquitin-protein ligase MARCHF7", "aln": "MESKPSRIPRRISVQPSGSLSTRMVSGN----------RGTSLNDSYHSRDSSFRLDSEYQ-----------------------SASASACASPCQPAWYSESEIPQGARARAQTQQR-------------DHDSKRPKLSCTNCASTSAGRNGGSGLNTVS--DSSWRHSQVPRS-----SSMVLGSFGTDLMRERRDLDRRRESSISNLMDYNHRSGDFTTSSYVQERVPSSYSQGARPKENAVSTLQLNSSSTNHQLPSDHQTVPSSRDSS--RSSFRSHFSPRQ---SESFRNSS-HPAFSYFSSRNETPTISNSER---------GSSQRPYRESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLSSEN--YISPRTLTS-QSRNNGTSSSSDVSEGRAAEASQGFRFLRRRWGLSSLSQNHSSEPEAENFNQESEGRNSGPWLSSSLRNRCTPLFSRRRREGRDESSRMSTSDVPPRSHIFR---RDSNEVVHLEAQGDSLGAAANRPQASGASS-SAAAGGSTPELPQGGRNPGLTGILPGSLFRFAVPPALGSNLADNVMITVDIIPSGWNSTDGKNDKAKSAPSRDPEKLQKIKESLLLEDSDDEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQECMKKWLQAKINSGSSLEAVTTCELCKEKLQLNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTIEPSTRVRFINLARTLQAHMEDLETSEDEF------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H992-1", "uniprot_id": "MARH7_HUMAN", "id": "Q9H992-1", "name": "E3 ubiquitin-protein ligase MARCHF7", "aln": "MESKPSRIPRRISVQPSSSLSARMMSGS----------RGSSLNDTYHSRDSSFRLDSEYQ-----------------------STSASASASPFQSAWYSESEITQGARSRSQNQQR-------------DHDSKRPKLSCTNCT-TSAGRNVGNGLNTLS--DSSWRHSQVPRS-----SSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVP-SYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDS---RNSLRSNFSSRE---SESSRSNT-QPGFSYSSSRDEAPIISNSERV--------VSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENS-YVSPRILTASQSRSNVPSAS-EVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFR---RESNEVVHLEAQNDPLGAAANRPQASAASS-SATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDS-EEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NG75-1", "uniprot_id": "A0A8M1NG75_DANRE", "id": "A0A8M1NG75-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MDSKSRRFPFAVSSSSSLSSPSSLSSSSSALSASRLYGRGSVLGRDRFSRDASVKLDSDYQGSRLLSSPRVYSSTESRHSNWKLSTPVTSSSSSSSSCDRSWTESSSGDRARLTDSERRLGTYCGLLGTSQDSESKRAKLSYTNREVYSRSPSTSKPATSYSTLGSSWKSSISPLSRSSSSSSSSSVSTQSEGLWARRDLEKRVDSGLSSLGESSYRPSSLTSSLYRSERVASTYAQGARPKDSQYSSHREN-SSSSRRIPSEYIPSPLERNSQRLTSDYQSNLFPRDTPRSSSTRTSTSVSDTSHHSSWSSTPYTALSACTSSPPSISPAPTPLPAQNTGESDGRGTTRRLLSR--------LFSRRSSQESNSTASTASDSRSYDSSPDEAPPTEAPPPISRENLEAELRNSDPAQAFSFLRRR-GPSLAPVQESTDVEPE---QESLRPPAG--LSWLNWNRCTPLFSRRRREGRDESARMDPHRSPQFSLGDRDGRKTPDQGTHCEDDDDEDDDDEDESSEGAAAGPSSGASALSASLLQDG--AHLAGRSHG-MGRGMNSPLFR--LPENVLIGVGVE--GRSQAD-EQPKDKPAPSRDPERLRKIQESLLLEES-DEEEGDLCRICQMGEQWSSNPLIEPCKCTGSLQYVHQDCIKKWLRSKISSGSNLEAITTCELCKEKLHLNIENFDINELYRSHE--RSEYEFISCGLYLVVLLHLCEQRFSDVLGAVNDAG----FFNLARTLHEHMDNLESSYAESDEDEVEDSRPSIDFCDLEDDDEEEEEEEEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**. *:* :* ..* * .: : *.. **: *. .***:*.:***:** *:..::.:*. .. * :* ..* *:* .:* * :***.*** ** * . . .. .: * .***: . * * ** * :: : ****::* :*.:*.* : .:*...:*:. * .:**. :*:******:. .: : * **:.:::**:: . .*:* .. :*:: .*: *.* *..: . *: ** ..:* : * .: * :::.:.:** ******** :*******:* .* * *:. * *. :. . * . : * ::.:*.* ***** * * . :.*:: :.* *** :* ** ******************:*: . . * * : .:: .* * :.* . .... ..*:. .: :.. :.. *.* . ::* * : * .* : *.:** * *.: * ..:* :. * *.*******:*:**:******:* :************. *** ****************:*:****::**.***.***:**********.**:*:***:**:*:* ::******.************* ***::* . :.. *:******: **::**:* : ", "identical_positions": 284, "similar_positions": 212, "identity": "35.59%" }, { "cls_id": "homologset.agr.MGI:1931054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ACD6B6L3-1", "uniprot_id": "A0ACD6B6L3_DANRE", "id": "A0ACD6B6L3-1", "name": "", "aln": "-----------------------------------------------------MFGCQGD-GLRVRSWFTLISGLVECLGFAGAVFGWASLVFVLKNEGYFSSLCVNTTING---TAVEDCSRQDEQFSLIFTIASFMNNFLTLPNGFLFDRFGTTVARLLG--ISVYSTGMLLIAFSTTASSILLFPALSFISVGGILFLMTNIQVGNLFGTHRSTIITLYNGAFDSSSAVFLIIKLLFEDG---VSLRGCFLFMACCSVIHLFRTFVLMPRT--HIPYPLPENYTYGIN---CGGTQDYTIAKVEEKNIQTSQAE--EEEAFTETSPQGQNTSKMER-------------------SFKSCFLSWFFLWHLLWLSVMQLRHYLFIGTLNPMLNHLTAGDPSLVSRYTNAFAFTQLCGILCAPWNGLLMDRHKGK----QREPGQSEQEADLKAAILSLSLTALQCVLFSVCAATPILPLQYLTFILQVLNRSFLYGGNAAFISVAFPSVHFGKLYGTVMALSAVVSLLQYPCFALIKGTLGGDPLYVNIGLTVL-SLLAFVNPLYVYLHCRRQATQRRAAKKTSSS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F4C3-1", "uniprot_id": "E7F4C3_DANRE", "id": "E7F4C3-1", "name": "", "aln": "-----------------------------------------------------MMAYKGSSGKVVRYKLTLATGLLECLCFAGVVFGWASLVFVLKTDGYFGDLCSNATDAGG--EFSSDCGLQDEHFSLVFTVASFMNNFLTLPNGFLYDHFGTMATRLLA--IFLYTTGTLIVAFSNKALSVLLFPALSFIAVGGILFLMTNMQVGNLFGSHRSTIITVYNGAFDSSSVIFLIIKVLYEKG---VSLRSSFLFLSACNLIHLIRTLFLMPKS--HIPYPIPQDYQYGIS---CAKSNSYNVEEYEAKREASSDRSRRAEEELLETDSIKLTDNPEKD-------------------SFRSCVLSWFFLWHLVWLSVMQLRHYFFIGTLNPMLNRLANQNPVTVSEYTNAFAFTQFCGVLCAPWNGLLMDRHKRK----PLDPDVSEREADLRSSILSLLLTSLQCFLFSICASIPFLPLQYLTFILQVLNRSFLYGGNAAFISIAFPARHFGKLYGLVMSLSAVVSLLQYPCFALNK-ALGGDPLYVNILLTIL-TLLAFIHPVYVFLHCRELAKHRENSRTLEASIQETSMY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AVZ9-1", "uniprot_id": "S43A3_MOUSE", "id": "A2AVZ9-1", "name": "Equilibrative nucleobase transporter 1", "aln": "----------------------------------------------------------MASKGLPLYLATLLTGLLECIGFAGVLFGWTSLLFVFKAENYFSEPCEQDCLLQSNVTGPSDLKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTTVARLIA--IFFYTCATIIIAFTSANTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITLYNGAFDSSSAVFLVIKLLYEQG---ISLRSSFIFMSVCSVWHIARTFLLMPKG--HIPYPLPPNYSYGLCSRFGASKKENKAAEHETKELRSKECLPPKEENSGPEQQQQQEQQQQQQQQQEQHE----------QHSFRRCALSRRFILHVVWLSIIQLWHYLFIGTLNSLLTKLSGGDKVEVSAYTNAFAITQFFGVLCAPWNGLLMDRLKQKYQKAAKRTGSSSEAVALCSMVPSLALTSLLSLGFALCASIPVMQLQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSAIVSLLQFPLFKVSPESN-----AVYVSMGLA-IFLTLVHPFLVYRECRAEKTKSSVDA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPJ3-1", "uniprot_id": "A0ABK0LPJ3_RAT", "id": "A0ABK0LPJ3-1", "name": "", "aln": "MAQGSRQTDPRHFLLNPETVGTRGLIEVECLPKEISYTPLPVVSEVQDRICGPTSPQTMASQ-LPLYLATFLTGLLECIGFAGVLFGWTSLLFVFKAENYFLKPCEQDCVLGGNTTGLPDLKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTAVARLLA--IFFYTCATLIIAFTSADTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITFYNGAFDSSSAVFLIIKLLYEQG---ISLRHSFIFLSVCSAWHVGRTFLLMPRG--HIPYPLPPNYSYGLCSRFCTRKEENEAAEHETKELQSRECQSPKEENSGPEQQQQQQQQQQQQQQQQQ------------QHSFRRCVFSHRFILHVVWLSIIQLWHYLFIGTLNSLLTKLAGEDSVKVSAYTNAFAITQFFGVLCAPWNGLLMDCLKQKYQKEAKRTGLSSEAVALCSMVPSLALTSLLSLGFTLCASIPVIELQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSAIVSLLQFPLFKVSPESK-----AVYVSMGLA-IFLTLVHPFLVYRECRVEKTKPSVDA------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBI5-1", "uniprot_id": "S43A3_HUMAN", "id": "Q8NBI5-1", "name": "Equilibrative nucleobase transporter 1", "aln": "----------------------------------------------------------MAGQGLPLHVATLLTGLLECLGFAGVLFGWPSLVFVFKNEDYFKDLCGPDAGPIGNATGQADCKAQDERFSLIFTLGSFMNNFMTFPTGYIFDRFKTTVARLIA--IFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRSTIITLYNGAFDSSSAVFLIIKLLYEKG---ISLRASFIFISVCSTWHVARTFLLMPRG--HIPYPLPPNYSYGLCPGNGTTKEEKETAEHENRELQSKEFLSAKEETPGAGQKQELR-------------------------SFWSYAFSRRFAWHLVWLSVIQLWHYLFIGTLNSLLTNMAGGDMARVSTYTNAFAFTQ-FGVLCAPWNGLLMDRLKQKYQKEARKTGSSTLAVALCSTVPSLALTSLLCLGFALCASVPILPLQYLTFILQVISRSFLYGSNAAFLTLAFPSEHFGKLFGLVMALSAVVSLLQFPIFTLIKGSLQNDPFYVNVMFMLA-ILLTFFHPFLVYRECRTWKESPSAIA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04991-1", "uniprot_id": "FMP42_YEAST", "id": "Q04991-1", "name": "Protein FMP42", "aln": "-----------------------------------------------------------MTSTRTLRYAQVACACIWCLFSAGIIFGFAALKPILISEGVYHELCDPKDGDR------LLCTAQDLKLNFIFALSATVTNIMALPVGKILDMYGPRVCGIIGSCLLFLASGNFISAKHLVSLWDPYLVGYTLLAVAGPFVFISCFQLANSFPQRSGTVLALLTGSFDSSSALFLLYRLLYQNWFPTLNVSRFFTLYLIVPVFILACQLTIMPHSSYKTVNHIAKIAVEGLDENGRLIEGDTGSGIIPDEQERQSLIAIEREEDSIPSRPQRRKSVLETYVEDKLQKKSGGIFGVLHGKSAYEQIKSPWFYLMLLFALVAMLRINYFIATVRTQEEYLLNDPDLALKLNSIFDMLLPLGGAVSIPFIGLLLD------------------HTDTLSTLTILFTTSTAIGVFGLIPNS--FTWNLIGIVLLVVYRPFYYTVVSDYSSKVFGFDTFGTVYGLLSCICGIFNMSQNLLDKWTHTTFNMNPFPINLTLVILTVVFSLTLTFYIRSQILPKPVNERGLSSNYQTI------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : *: ** :**:.:* :: :. : . * ** ::.::*::.: :.*::::* * : * : . . ::. : . : . :: * : . .::::.* :.::: :*:.* * : .*:::. .*:*****.:**: ::*::. :.: * : : : :**: : :. *: . .. ** * * * ::: : * **.*:.. : :. : : * :. *: ***:* . : : * *: * : . : : ::* *: *.* * : : : .* **.::* : .:..:..: * : : : : : .::: .. : . ", "identical_positions": 61, "similar_positions": 147, "identity": "10.25%" }, { "cls_id": "homologset.agr.MGI:1931071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLR1-1", "uniprot_id": "S61A2_MOUSE", "id": "Q9JLR1-1", "name": "Protein transport protein Sec61 subunit alpha isoform 2", "aln": "-MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRG--TEFEGAVIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNLLG-QWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QAEVGGMGALFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9S3-1", "uniprot_id": "S61A2_HUMAN", "id": "Q9H9S3-1", "name": "Protein transport protein Sec61 subunit alpha isoform 2", "aln": "-MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRG--TEFEGAVIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNLLG-QWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QAEVGGMGALFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61621-1", "uniprot_id": "S61A1_RAT", "id": "P61621-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32915-1", "uniprot_id": "SC61A_YEAST", "id": "P32915-1", "name": "Protein transport protein SEC61", "aln": "MSSNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVS--LLIFLILGQIPLYGIVSSETSDPLYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCAIILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGISLFTATNIAEQIFWRAFAPTTVNSGRG--KEFEGAVIAFFHLLAVRKDKKR-ALVEAFYRTNLPNMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRGQIGIYPIKLFYTSNTPIMLQSALTSNIFLISQILFQKYPTNPLIRLIG-VWG-IRPGTQGPQMALSGLAYYIQPLMSLSEALLDPIKTIVYITFVLGSCAVFSKTWIEISGTSPRDIAKQFKDQGMVINGKRETSIYRELKKIIPTAAAFGGATIGALSVGSDLLGTLGSGASILMATTTIYGYYEAAAKEGGFT-----KNLVPGFSDLM-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38353-1", "uniprot_id": "SSH1_YEAST", "id": "P38353-1", "name": "Sec sixty-one protein homolog", "aln": "MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYLFAQFPLVGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKVIKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFG--DDLSVVQIGLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGVSQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIISAFNRDYLPNLTTTIIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVLFSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLLAPPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEFKDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKAAGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.:::.**: .***: * .*: : :*:::* .: : :* : * :.: **:*::* ::..: **:*:*: * ::*.:*:*:* * ::::: . .** **: *: .:: : : : :::* :* ::. *: :**. *.::. ** *::.**:*:.** :: :. *. :. :*. : :: *.. * :**:* ::: * : .. .: .** * ***: : .: : .* *:*..* :***:*:: ** . *****:**. .:::. :: :.::: :* . * :: . . . *. * : :*: :.* *:* : *:..* :**:*.:*:* ::*:* :.: *:*: .: :**:: ** **. *. :. ::* .: ** *..:.*::. : : * . * * .. : ", "identical_positions": 109, "similar_positions": 187, "identity": "22.11%" }, { "cls_id": "homologset.agr.MGI:1931086", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8Q5-1", "uniprot_id": "D3Z8Q5_RAT", "id": "D3Z8Q5-1", "name": "", "aln": "-MGASGSKARG---LWPFASTT---------------GGGGPEAAGAEQSLVRSRA-RAVPPFVFTRRGSMFYDEDGDLAHEFYEETIVTKNGQKRAKLRRVHKNLIPQGIVKLD--PPR----IHVDFPVILYEV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVF8-1", "uniprot_id": "TUSC2_MOUSE", "id": "Q9WVF8-1", "name": "Tumor suppressor candidate 2", "aln": "-MGASGSKARG---LWPFASTP---------------GGGGPEAAGSEQSLVRSRA-RAVPPFVFTRRGSMFYDEDGDLAHEFYEETIVTKNGQKRAKLRRVHKNLIPQGIVKLD--PPR----IHVDFPVILYEV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1NBI1-1", "uniprot_id": "A0A8M1NBI1_DANRE", "id": "A0A8M1NBI1-1", "name": "", "aln": "-MGGSGSKPKG---VWPFTSSA---------------AGGEAPGEGSEQCLARLRGSKNATPFVFTRRSSLYFDEDGDLAHEFYEETVVTKNGRKKAKLKRIQKNLIPQGIVKLD--HPR----IHVDFPVILCEI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O75896-1", "uniprot_id": "TUSC2_HUMAN", "id": "O75896-1", "name": "Tumor suppressor candidate 2", "aln": "-MGASGSKARG---LWPFASAA---------------GGGGSEAAGAEQALVRPRG-RAVPPFVFTRRGSMFYDEDGDLAHEFYEETIVTKNGQKRAKLRRVHKNLIPQGIVKLD--HPR----IHVDFPVILYEV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M0E7-1", "uniprot_id": "A0ABK0M0E7_RAT", "id": "A0ABK0M0E7-1", "name": "", "aln": "MFTDEEWKRKDALIVSTFIQLIREEPTYEPRLAIFCFGVGSPVAEVAKQSLVRSRA-RAVPPFVFTRRGSMFYDEDGDLAHEFYEETIITKNGQKRSNLRDL-KFLSYRLCICFDSTTPRTLSSINLEWSYYPGTHPGL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * :. : .* . . * . . ::*.*.* *. : ..*******.*:::**************::****:*:::*: : * * : : :* ** *::::. ", "identical_positions": 41, "similar_positions": 38, "identity": "29.5%" }, { "cls_id": "homologset.agr.MGI:1931123", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62784-1", "uniprot_id": "INP4A_RAT", "id": "Q62784-1", "name": "Inositol polyphosphate-4-phosphatase type I A", "aln": "-------------------------------------------------------------------------------------------------------MTAREHSPRHGARARAMQRASTIDVTADMVGLSLAGNIQDPDE------------------------------------------------------PILEFSLACSELHTPSLDRKPNSFVAVSVTTPP--QAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQIKLSVYDVKDRSQGTMYLLGSGTFVVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQ---------------QPPVTRSLDTVNGRMVLPVDESLTEALGIRSKYASLRKDSLLKAVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYK--GPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQ-NYDVVTIGAPAAH-CQGFKSGGLRKKLHKFEEAKKHSFEECCTSSTC----------------QSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP---------------------------------DYIASKASPTSTEEEQVMLRNDQDTLMARWAGR-------------SSRSSLQVDWHEEEWEKVWLNVDKS---------LECIIQRVDKLLQKERLHGEGG---EDVFPCSS-TCSSKK-------------------------------------------------------------------------------------------DCSPPP-----------EESCPGEWSEALYPLLTTLTDCVAMMSDKAKAAMVFLLMQTAAPTIASYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDGGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSNASSDMLPVITGNRDGFNVRIPLPGPLFDSLPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEVCRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVG----SRKYAFNSLQLKAFPKHYRPP-----------EGTYGKVET-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPW0-1", "uniprot_id": "INP4A_MOUSE", "id": "Q9EPW0-1", "name": "Inositol polyphosphate-4-phosphatase type I A", "aln": "-------------------------------------------------------------------------------------------------------MTAREHSPRHGARARAMQRASTIDVAADMVGLSLAGNIQDPDE------------------------------------------------------PILEFSLACSELHTPSLDRKPNSFVAVSVTTPP--QAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQIKLSVYDVKDRSQGTMYLLGSGTFVVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQ---------------QPPVTRFLDTVNGRMVLPVDESLTEALGIRSKYAFLRKDSLLKAVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYK--GPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQ-NYDVVTIGAPAAH-CQGFKSGGLRKKLHKFEEAKKHSFEECCTSSSG----------------QSIIYIPQDITRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP---------------------------------DYIASKASPTSTEEEQVMLRNDQDTLMARWAGR-------------SSRSSLQVDWHEEEWQKVWLNVDKS---------LECIIQRVDKLLQKDRLHGEGC---EDAFPCSS-TCSSKK-------------------------------------------------------------------------------------------DCSPPP-----------EESSPGEWSEALYPLLTTLTDCVAMMSDKAKAAMVFLLMQDSAPTIASYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDGGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSNASSDMLPVITGNRDGFNVRIPLPGPLVDSFPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEGINGESLVRVNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEVCRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVG----SRKYAFNSLQLKAFPKHYRPP-----------EGTYGKVET-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PE3-1", "uniprot_id": "INP4A_HUMAN", "id": "Q96PE3-1", "name": "Inositol polyphosphate-4-phosphatase type I A", "aln": "-------------------------------------------------------------------------------------------------------MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDE------------------------------------------------------PILEFSLACSELHTPSLDRKPNSFVAVSVTTPP--QAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQ---------------RPPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYR--GPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQ-NYDIVTIGAPAAH-CQGFKSGGLRKKLHKFEETKKH-FEECCTSSGC----------------QSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP---------------------------------DYIASKASPTSTEEEQVMLRNDQDTLMARWTGR-------------NSRSSLQVDWHEEEWEKVWLNVDKS---------LECIIQRVDKLLQKERLHGEGC---EDVFPCAG-SCTSKKGNPDSHAYWIRP----------------------------------------------------EDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPP-----------EESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVG----SRKYAFNSLQLKAFPKHYRPP-----------EGTYGKVET-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GEZ8-1", "uniprot_id": "A0AC58GEZ8_DANRE", "id": "A0AC58GEZ8-1", "name": "Inositol polyphosphate-4-phosphatase type I A", "aln": "-------------------------------------------------------------------------------------------------------MAGRERSPRH--RPWSVYRANTFDLSSEMMGLALTGNSQDPDE------------------------------------------------------PVLEFSLACSELVTPSLDRKPSSFVAVSCTTPP--QAFWTKHAQTEIIEGTSNPIFLSSIAFFQDSLITQQTQIKLSVYDVKDRSQGTMYLLGSAMFTVKELLQDKHHRLHLMLKSAESERMGNITIIGWQIEERRDQ---------------RAPLAR-SDTVNGRMVLPVDESLTESMGVKAKSASLCKDSLLKAVFGGTVSRMYRLPTTDGNHLRVLEQMAESVLSLHIPRQFVKLLLEEDAARVCELEELGELSPCWENLRRQIITQYQTIILTYQETLSNLHEYK--GASFKSSTLKGEKKLEFMPTNLHVQRMRVQGESGYDR-TYDVVTTGAPAAH-HQGFKGSGLRKLIQKFEEAKKHAFEGEG-VGESA--------------PLSMRYQPQDVLKAKEIISHINTLKTQVSYYTERLSRAAKERSTNALERTLAILTDKTRQLVTVCDSKLLTTAIQALSAARP---------------------------------EFIASRGSPSAHDTERVVLRNDQGSPQAKWSGK-------------GNRASVNLTWQEEEWEKIWLNVDKS---------LECVIRCVDRLLTRERMHSDSS---EDVFLSDQQADTSKRGS-KGNAFWINP--------------------------------------------------GDGLSSPSSSHPLSAPSLSPSSSP-FLNPACPSTPNTHSYNASVEG--SSPGEWSEALYPLLTTLNECVAMMSDKAKKSMVFLLMQDSAPTIAMSLSLQYRRDVVFCQTLTALICGFVVKLRNCLSDSGFLRQLHTIGLLVQFEGLLSTYGEELAMLEDMSVGVMDLRNVTFKITQATSSFSPDMLPVITGNRDGFNVRIPLPGVMFDALPREIQNGMLLRVQPVLFNVGINEQQTLAEKFGDTSLQEVVNMESLARLTSYYDQFKEVLPEDCLPRSRSQNCVPELLRFLSQNINARKSKNVDILLQAAEICRRLNGVRVTSCKSAKDRTAMSVTLEQCQILQSEHCMAPQVFTQALDCMRSEGCRRENTMKNVG----SRKYAFNSLQLKTFPKQYRPP-----------EGTFGKVET-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JSJ9-1", "uniprot_id": "A0AC58JSJ9_DANRE", "id": "A0AC58JSJ9-1", "name": "Inositol polyphosphate-4-phosphatase type I A", "aln": "-------------------------------------------------------------------------------------------------------MSRRER-------PWSVYRSNTLELASEMLGLALEGNSQDPDE------------------------------------------------------PVLEFSLVCSELTTPSLDRKPNSFVAVSCTTPP--QAFWTKHAQTEIIEGTNNPMFLSSVAFFQDSHINQHTQVKLSVYDVKDRSQGTMYLLGSAMFPVKELLQEKNHRLNIPLRSAENKHVGSITVIAWQLEEKRDH---------------HTPIKQLQDTFNGRTVLPVDESLTESVGVRAKYASLWKDSFLRSVFGGTMSRMYRFPTTDGNHLRILEQMAESVLSLNVPRQFVKLLLEEDSARVSELEELGELSPCWENLRRQIVTQYQSILLSYQDTRSDLQDYK--GPSFKASNLKAERKLEFMPTNLHVQRMRVQDESGCDH-TYDVVTIGAPAAH-CQGFKSGGLRKLLQKFEEAKKVIYEEECSSALSS--------------SQSIVYIPQDIVRAKEIISHINTLKTQVSYYAERLSRAAKERSANGMERTLAILADKTRQLVTVCDCKLLASAVQALNAARP---------------------------------EYIASKNSPSA-DSEQVVLRNDQDTLLAKWSGS-------------NSRSSLHVDWHEEEWEKVWGNVDKS---------LECIIQRVDKLLQRERLHSSSS---EDMFQSDQQGGTSKKGNGKRKAFWVNPT----------------------------------CMEKSSSAPEPQQLSPSPPSSSSSSSSSSSSSSSPSSSPSDLNPACPDNPEVHAYGSSSSGEESYPGEWSEALYPLLTTLTECVAMMSDKAKKSMVFLLMQDSAPTIAMDLSLQYRRDVVFCQTLTALICGFIIKLRNCLRDDGFLRQLYTIGLLAQFECLLSTYGEELAMLEDMSIGIMDLRNVTFKVTQAISTSSPDMLPVITGNRDGFNVRIPLPGSMFDALPREIQNGMLLRVQPVLFNVGINEQQTLAEKFGDTSLQELINVESLARLNSYYQQFKEVLPDDCLPHSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALDCMRSIGTREGVTQKNLSGLLPVRDFRLDPSLLYSLPLLALSPNLLIVWVFLSIAYLLAKLRCS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY47-1", "uniprot_id": "Q9VY47_DROME", "id": "Q9VY47-1", "name": "phosphatidylinositol-3,4-bisphosphate 4-phosphatase", "aln": "MRFNKPELNSLASNPATRFDKEGLLIITDRQEGFLWRSSEVRVERWCKLRGNLLFYLKDKDPKSAVAGLLVLENCRARIQNEERDSEGYVFDLDFKDSPSERFITRSSAERLAWVQCIEHASSEKLNALIRQLKEQIVSQSRQPSSGASSSMGNHIDLGMPLEQQMQEQLQLHGQPAEELSVPVPTEVVAPFEELDLSELPICETALSCDTLPLDTLGRPPNPQVVCSLLPTAGEDCVWREHARTELQERTRTPQFLCTMRFQRSAGLSASTRLRFSVFDVRERMTLTAVPLGHAEVALGVIQDTSRLRLPLTSPRGE---CGFITLASWSPDAAVEPGQSGNGPPRSSTQLFDGSAGAGGATTSSRRAHRRTQSLPPKLGVRLFVPQQCG---LQRVCSNPRLRTYRLHSSLGADISVQETLLESRLCCQLPQQLLSIWIQREKELLQEISGMGELSGEWRWRQMNLLEEHLRLLKDYSQAKQNIQQLARDGVSFKRSSAKADESLEFLPVNLHVQRMWAQNDTLQRRGLLDVVTVGAFTRHDPKGRKCGGLIKLLQESKSWKLEQSNACKVQAANDAVQATKQLRKEIVELMSQLLQLASRRSSMDMMPLCNQMVARTRTLLNLWEPSIVEEAVAFIERHRIIEEPENVLMEPMSPFRKITQQLTALELKSPELEDFATPVVAPPDLWPRGQPPLMRSNSWHPSNSSPSSSLDIRAIDSLQHVVKCYNDHLRSLEQGRQPGRQADDEEQEEATYQSLPVAWQTQSEVSAGTQIPPSDNPADLSVLQLIDLDEIGRQAQRQRHHQPPAGFLDTKLMSSSPSANYYRPTEEPEPLDLTQLNIEASVMCLVSKLKFFCGRCDSPAIRLRHPKAPIKREGFAVAPQQAPDVIAASAASGKQAPNLALDLKPQSVDSDGITTTGSVAVKKGNKFTDGLDLSMTTDWAAELRPSMRKLRHAMDRLLKTARLMHSVQRLQQDMRCNRLQASIMYRRDVCFSQALTALVSSLMLRLWGSELDMGYLVMLRDLGPLAYFEGLLTLYGNEADMWSDMCIAIEDLSAVSFQLVRAQGEVAQTPTPRITGSRQALEVQLPVPEHSLPGNGNSIS----FKITPVFFNIGINEKASFAETLGQTKEQHRSNWDNYLRLSQYFGRYRKLG----LGSVDTGESLQSLLGFMEQQLRANVSKNVKILHLAEDACRLMDGLRFTSCKSAKDRTGMAVTLEQCRVLVREFQLPAKHVPYALSTMRSEGTRMDNVLKNIG----KRKYAFNRTQVSFLPAMYRPP-----------VGSYGKAQT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :..:: : : .: ::*.. *: * :* *. * :*.* *.. *. * ... :..* :**:**: * * .* **.:: * :.: :. *::::**:**::* * ** . . : : : . ** : .* * **: .*. : : . * ..* . :**. :*:: . *: * ... * **: :: * .: : * : ** *. ::*:*::.: ::.: : *:. :**** *. : ::: :: :: *.: :::: * *** *. *.:..***:*.***:*** .*.: : *:** ** : * :* * .** * ::: :. * : . * . : :::. * : ::. : . : :.:. :** * :. : .:. : :: : .*. * . :* . : : : ::: :. : * . *: : *: :. . :: * : :.: ::* * : : . . : . * . :*: * * : .* ..: : ..*: . :* *: ***** *.*:****:..::::* .. * *:* * :* *. ** **: **:* * .**.:.: ** *:*::.:* . : * ***.*:.::*::*:* . . ..*. ::: **:**:****: ::** :*:*. *. * :. *:..*: ::::: * : .: .** *: *::.*. .***.** * : ** ::*:*.**********.*:****** :* *. :..: .. **. *** * * . **:. *.: :: : :* .* .* . ", "identical_positions": 219, "similar_positions": 318, "identity": "16.72%" }, { "cls_id": "homologset.agr.MGI:1931130", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99N14-1", "uniprot_id": "TKN4_MOUSE", "id": "Q99N14-1", "name": "Tachykinin-4", "aln": "MLPLLALLLLIGPSVCTTAGDR-EELAFGAEAESWVTVNLKGIPVPSIELKLQELKRSRTRQFYGLMGKRVG-----------GYQLGRIVQDLLGTRGLSIEGTCRQAASQQRARPGAVTRESLQSR-------------------EEDE-----APLTTSNV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CH01-1", "uniprot_id": "TKN4_RAT", "id": "Q8CH01-1", "name": "Tachykinin-4", "aln": "MLPLLALFLLIGPAVSTTTRDR-EDLTFGAEAESWVTVNLKGIPVPSIELKLQELKRSRTRQFYGLMGKRVEGVHPIQSAERTGYQLGRIVQDLLGTRGLSIEGSCRQETNHQSAGPGAVARESLQSQRGRSEPPNHQQHVALSLGTEEDDQSSERAPRDASQMMPRPSRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86UU9-1", "uniprot_id": "TKN4_HUMAN", "id": "Q86UU9-1", "name": "Tachykinin-4", "aln": "MLPCLALLLLMELSVCTVAGDGGEEQTLSTEAETWVIVALEEGAGPSIQLQLQEVKTGKASQFFGLMGKRVGGRPLIQPRRKKAYQLEHTFQGLLGKRSLFTEG--REDEAQGSE--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ***:**: :*.*.: * *: ::.:***:** * *: . ***:*:***:* .:: **:******* .*** : .*.***.*.* ** *: : ", "identical_positions": 48, "similar_positions": 29, "identity": "28.07%" }, { "cls_id": "homologset.agr.MGI:1931139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MC0-1", "uniprot_id": "PP14A_RAT", "id": "Q99MC0-1", "name": "Protein phosphatase 1 regulatory subunit 14A", "aln": "--MAAQRLGKRVLSKLQSPSRARGPGGSPSGLQKRHARVTVKYDRREL---QRRLDVEKWIDGRLEELYRGREADMPDEVNIDELLELDSEEERCRKIRGLLEACLNP---TEDFVQELLAKLRGLHKQPGFPQPSPSDDPSLSPRQDPAHTAPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VC7-1", "uniprot_id": "PP14A_MOUSE", "id": "Q91VC7-1", "name": "Protein phosphatase 1 regulatory subunit 14A", "aln": "--MAAQRLGKRVLSKLQSPSRARGPGGSPSGLQKRHARVTVKYDRREL---QRRLDVEKWIDGCLEELYRGRESDMPDEVNIDELLELDSEEERCRKIQGLLEACANP---TEDFVQELLAKLRGLHKQPGFPQPSPSDDPSLSPRQDRAHTAPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A00-1", "uniprot_id": "PP14A_HUMAN", "id": "Q96A00-1", "name": "Protein phosphatase 1 regulatory subunit 14A", "aln": "--MAAQRLGKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRREL---QRRLDVEKWIDGRLEELYRGMEADMPDEINIDELLELESEEERSRKIQGLLKSCGKP---VEDFIQELLAKLQGLHRQPGLRQPSPSHDGSLSPLQDRARTAHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKQ5-1", "uniprot_id": "Q9VKQ5_DROME", "id": "Q9VKQ5-1", "name": "", "aln": "MQCGLEQMNDCERSPNRTNLRVNFNEKGAEVKERREKFLTAKYGSHQMSLIRKRLAVEMWLYDELQKLFD--PPNEAIDVDIDEILDMDTDDIRRSHLIRLLSVCKRPQSDISKFIGDLLDRAKTL-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::.. * :: *.. .. ::*. :*.**. ::: ::** ** *: . *::*: .: . :::***:*:::::: * :: **. * .* ..*: :** : : * ", "identical_positions": 26, "similar_positions": 51, "identity": "16.77%" }, { "cls_id": "homologset.agr.MGI:1931144", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HB97-1", "uniprot_id": "PARVA_RAT", "id": "Q9HB97-1", "name": "Alpha-parvin", "aln": "MATSPQKSPSVPKSP-TPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINEALKLPPRSIKWNVDSVHAKNLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPC1-1", "uniprot_id": "PARVA_MOUSE", "id": "Q9EPC1-1", "name": "Alpha-parvin", "aln": "MATSPQKSPLVPKSP-TPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTLLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKNLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVD7-1", "uniprot_id": "PARVA_HUMAN", "id": "Q9NVD7-1", "name": "Alpha-parvin", "aln": "MATSPQKSPSVPKSP-TPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWD0-1", "uniprot_id": "Q9VWD0_DROME", "id": "Q9VWD0-1", "name": "", "aln": "MSTLNR-----PKSPHTPTAIKKGEKEDSFWDKFS-TLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYALREHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKKLDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPVRLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRDFA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* : **** **.: . :*:*** .*:. **.*:: ::**.:.**** **: * ** ::: *** *.*:* *:::**:* .**:: :* ::*:***** *. :****:.* **:******:**:*** .:**:*.****** .*::**: **: :*.:* : : **.* ***:*.:********** ::****:***::* : **:.:*. *:*:::::**:**.: : *. * *:******:* ***** ****:********* ***:*:::*:*:* ***** ****** *:*****.*.***:..:* * **:***:**** ** ***.******* **********.*** :*:. ", "identical_positions": 208, "similar_positions": 104, "identity": "55.76%" }, { "cls_id": "homologset.agr.MGI:1931148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00746-1", "uniprot_id": "NDKD_HUMAN", "id": "O00746-1", "name": "Nucleoside diphosphate kinase D, mitochondrial", "aln": "MGGLFWR-----SALRGLRCGPRAPGPSLLVRHGSGGPSWT--RERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WV84-1", "uniprot_id": "NDKD_MOUSE", "id": "Q9WV84-1", "name": "Nucleoside diphosphate kinase D, mitochondrial", "aln": "MGSLFGRV----AALRALLCGPRFQ--CLLVRPSSGGPPWP--QERTLVAVKPDGVQRRLVGTVIQRFERRGFKLVGMKMLQAPESILAEHYRDLQRKPFYPALISYMSSGPVVAMVWEGPNVVHISRAMIGHTDSTEAAPGTIRGDFSVHISRNVIHASDSVDGAQREIELWFQSSELLNWADGGHHSSCYPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB40E4T4-1", "uniprot_id": "A0AB40E4T4_DANRE", "id": "A0AB40E4T4-1", "name": "Nucleoside diphosphate kinase", "aln": "MNMMAVRFGLRVHAARAVTRNPSRALGIGAARSLSSDSDFSGVNERTLVAVKPDGVQRRLIGEVIKRFEQRGFRLVGLKMLQAPDKLLAQHYVSLQKKPFYSSLLYYMTSGPIVAMVWEGHNVVKTSRMMVGDTDPAAAAPGTIRGDFSVHISRNVVHASDSVEGAQREISLWFHRSELVDWE-GCDHKNIYHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : * * *.: .* .* *... :. .****************:* **:***:*** ***:******:.:**:** .*::****.:*: **:***:******* ***: ** *:*.**.: ******************:******:******.***: ***:.* * .*.. : ", "identical_positions": 111, "similar_positions": 43, "identity": "57.22%" }, { "cls_id": "homologset.agr.MGI:1931221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKV0-1", "uniprot_id": "HDAC9_HUMAN", "id": "Q9UKV0-1", "name": "Histone deacetylase 9", "aln": "MHSMISSVDVKSEVPVGLEPISPLDLRTDLRMMMPVVDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHIK---ELLAIKQQQELLEKEQKLEQQRQEQEVERHRREQQLPPLRGKDRGRE---RAVASTEVKQKLQEFLLSKSATKDTPTNGKNHSVSRHPKLWYTAAHHTSLDQSSPPLSGTSPSYKYTLPGAQDAKDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGNVVTSFKKRMFEVTESSVSSSSPGSGPSSPNNGPTGSVTENETSVLPPTPHAEQMVSQQRILIHEDSMNLLSLYTSPSLPNITLGLPAVPSQLNASNSLKEKQKCETQTLRQGVPLPGQYGGSIPASSSHPHVTLEGKPPNSSHQALLQHLLLKEQMRQQKLLVAGGVPLHPQSPLATKERISPGIRGTHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQIHMNKLLSKSIEQLKQPGSHLEEAEEELQ---GDQAMQEDRAPS----SGNSTRSDSSACVDDTLGQVGAVKVKEEPVDSDEDAQIQEMESGEQAAFMQQPFLEPTHTRALSVRQAPLAAVGMDGLEKHRLVSRTHSSPAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSMSLKFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99N13-1", "uniprot_id": "HDAC9_MOUSE", "id": "Q99N13-1", "name": "Histone deacetylase 9", "aln": "MHSMISSVDVKSEVPMGLEPISPLDLRTDLRMMMPVVDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHIK---ELLAIKQQQELLEKEQKLEQQRQEQEVERHRREQQLPPLRGKDRGRE---RAVASTEVKQKLQEFLLSKSATKDTPTNGKNHSVGRHPKLWYTAAHHTSLDQSSPPLSGTSPSYKYTLPGAQDSKDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGNLVTSFKKRVFEVAESSVSSSSPGSGPSSPNNGPAGNVTENEASALPPTPHPEQLVPQQRILIHEDSMNLLSLYTSPSLPNITLGLPAVPSPLNASNSLKDKQKCETQMLRQGVPLPSQYGSSIAASSSHVHVAMEGKP-NSSHQALLQHLLLKEQMRQQKLLVAGGVPLHPQSPLATKERISPGIRGTHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQIHMNKLLSKSIEQLKQPGSHLEEAEEELQ---GDQSM-EDRAAS----KDNSARSDSSACVEDTLGQVGAVKVKEEPVDSDEDAQIQEMECGEQAAFMQQ-----------------------------------------------VIGKDLAPGFVIKVII--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PBI4-1", "uniprot_id": "HDA9B_DANRE", "id": "Q6PBI4-1", "name": "Histone deacetylase 9-B", "aln": "MHNVNNSVDIKPEVPLALDPGSPLDLRTDIRMQGSASEVTVWERQLQQELLLIQKQQQIQKQLLITEFQKQHENLVRQHQAQIQEHLKLQQELHVMKQQQEQLEKERKLELQSQERELERHRREQQVLVLRNRERTRESLTGAVASNEVKQKLQEFLLSKS-TKDITLNGIPQKITQSSKLWYTASHHTSLEQSSPPLGGASSSCKISLPSPQDYRDDFPLRKTVSEPNLKVRSRLKQKVAERRSSPLLRRKEGNIMTPFKKRALELLESTASSSAPGSGPSSPNGACSALGAENGPSSLPVTTRTERWPSQSRLLGPESSVSMLNLYTSPSLPNISLGFSAASSPISAALGLQEKHVDNGAVSAVIQGLPTQLLGPVPLSVMETKVS-------SSHQALLQHLLQKEQLRHQKILSSGQSPVHPPSPLAMMENSPSSTR--PKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQNFLEKQKQYQQQVHINKMLSKSIEQLRQPNVHLQESEEEEGEDCQEHAMQEESSPSGGVIRKHSPQNTSRSPTIPLDSHPGVIRVKEEPGASDD----ETMAN--QSSYIHQ----------------------------------------------------VKGRMVIQAMI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: .***:*.***:.*:* ********:** .. : .* *:**********:**********:*********.******:***:* ** .:***** ****:*** * **:*:********: **.::* ** ****.************** *** . ** :.: : .******:*****:******.*:*.* * :**..** :********.***************************:**::*.**** :*: **:.***:*********.. :. :** .* ** *.:.*: .*.*:* *.*:.:*.**********:**:.*..* :.*: .*::*: : ** * ..:. * . :*: *********** ***:*:**:* :* *:** **** *. ... * *******************************:***********:*:**:********:**. **:*:*** :::* *: :.* :*.:. * : . .: *.::***** **: : * *:::::* : . ", "identical_positions": 338, "similar_positions": 135, "identity": "33.01%" }, { "cls_id": "homologset.agr.MGI:1931224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63043-1", "uniprot_id": "STMN4_RAT", "id": "P63043-1", "name": "Stathmin-4", "aln": "-------------------------------------------------MTLAAYKEKMKELPLVSLFCSCFLSDPLNK-----------SSYKYEADTVDLNWCVIS-------------------------DMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63042-1", "uniprot_id": "STMN4_MOUSE", "id": "P63042-1", "name": "Stathmin-4", "aln": "-------------------------------------------------MTLAAYKEKMKELPLVSLFCSCFLSDPLNK-----------SSYKYEADTVDLNWCVIS-------------------------DMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H169-1", "uniprot_id": "STMN4_HUMAN", "id": "Q9H169-1", "name": "Stathmin-4", "aln": "-------------------------------------------------MTLAAYKEKMKELPLVSLFCSCFLADPLNK-----------SSYKYEADTVDLNWCVIS-------------------------DMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIC7-1", "uniprot_id": "Q5RIC7_DANRE", "id": "Q5RIC7-1", "name": "Stathmin", "aln": "-------------------------------------------------MTLAAYRDKVKELPLVSLLCSCINSNRAEN-----------PTYK-AEDAVDLNWCVIK-------------------------EMEVIELNKRTSGQAFEVILKPPSFDVAPELNTSMPQRKDPSLEEIQKKLEAAEERRKFQEAEMLKHLAEKREHEREVIQKAFEENNNFIKNAKEKLEQRMEANKENREALLAAMLERLQEKDKHAEEVRKNKELKEEACR------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NEA1-1", "uniprot_id": "M9NEA1_DROME", "id": "M9NEA1-1", "name": "", "aln": "MGCNFSALPTKCKGCGQIRADFDRRYGCSECGSEVMYCGQCFDEGRNQHTETHKDDRRIKIIYHRSFLDKFFSGEKLLNGDASKSYNCVFCKKRFSAEELQLHLSEMHSNPADASALTVMLERMRQEDLENRIATEIRCQEKSRGGLSYEVILAEPAPNVAVPKRPVTPG-KNVSVEEIEQKLKAAEERRISLEAKKMADISTKLAKVEEATRKKDEITNEFITQTKEQLESKMELHVEKREAIISDMKEKLKIHAQDIEKTRETLEQQKANEQKAIEEKLKIAQSLRDENIKKMLDRLKEHNTIKIAEIKSQNDQLECQKIEEKARIYENKLFAAEQKREKELQKKIEKVQKLERRAELVRQNKAQAQDLDGQQSAIASSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : *:: . : .: : . : : ::*: . : *: :* .* ::**** *: : . .. * :: *:***::**:****** **: : .:: * : .*. :* * .*:**. :**:* .:** : *:*** :: * *:*: : :. *:.*:. * :: : ", "identical_positions": 48, "similar_positions": 66, "identity": "12.57%" }, { "cls_id": "homologset.agr.MGI:1931237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WL8-1", "uniprot_id": "WWOX_MOUSE", "id": "Q91WL8-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHKAK--VEAMTLDLAVLRSVQHFAEAFKAKNVSLHVLVCNAGTFALPWGLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSSPARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSAIHRNS--------WVYKLLFTLARPFTKSMQQGAATTVYCAVAP--ELEGLGGMYFNN-CCRCLPSEEAQSEETARALWELSERLIQDRLGSPSS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LQK5-1", "uniprot_id": "A0ABK0LQK5_RAT", "id": "A0ABK0LQK5-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNMSRASEAVSRILEEWHKAK--VEAMTLDLAVLRSVQHFAEAFKAKNVPLHILVCNAGTFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSSGKLDLSRLSLSSSDYWAMLAYNRSKLCNILFSNELHRLLSPRGVTSNALHPGNMMFSAIHRNS--------WVYKLLFTLARPFTKSMQQGAATTVYCAVAP--ELEGLGGMYFNN-CCRCLPSEEAQNEETARALWELSERLIQDRLGSPSS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZC7-1", "uniprot_id": "WWOX_HUMAN", "id": "Q9NZC7-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAK--VEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSW--------WVYTLLFTLARPFTKSMQQGAATTVYCAAVP--ELEGLGGMYFNN-CCRCMPSPEAQSEETARTLWALSERLIQERLGSQSG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803A8-1", "uniprot_id": "WWOX_DANRE", "id": "Q803A8-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALKYAGMEDTDSEDELPPGWEERSTKDGWVYYANHEEMKTQWEHPKTGKKKRCAGALPYGWEQETDDKGQ-IFYVDHINKRKTYFDPRQAFTVED-MQVKP---KRYDGNTGALEILHGQDLSDKVIIVTGANSGIGFETARSFALHGAHVILACRNQSRASKAASLIMGEWSKAR--VEVLPLDLASLRSVRQFAELFKATKLPLHVLVCNAAVCSQPWRLTEDGFESTFQICHLGHFLLVQLLQDVLRLSAPARVVVVSSESHRFTDLLDSCGNLDLDLLSPPQKNYWSLLAYNRAKLCNLLFSSELHRRMSPHGICCNALHPGSMMFTSIHRSW--------WLLTLLFSLARPFTKSMQQGAATTVYCAVAP--ELEGIGGMYFNN-CFRCLPSPQAQDPAAALSLWELSERLVQERSTPPQVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU5-1", "uniprot_id": "WWOX_DROME", "id": "Q9VLU5-1", "name": "WW domain-containing oxidoreductase", "aln": "MIALP-----DTDSEDELPPGWEERATDDGTVCYVNQQGKTSQWTHPRTGRSKRITGELPLGWEKYYDEQGKRFMFLNKETQQRTNVDPRLAFAVEEPTQNVAQVRQRFDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETLFDYKT--RIIVLSSESHRFANLP--VENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWKQRGISVFSLHPGNMVSSDLSRNY--------WFYRLLFAIVRPFTKSLQQAAATSIYCATAN--ELTGLSGLYFNN-CFFCEPSKLSKSAALQQQLWKLSENLIAELVEQEQH-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08651-1", "uniprot_id": "ENV9_YEAST", "id": "Q08651-1", "name": "Probable oxidoreductase ENV9", "aln": "-------------------------------------------------------------------------------------MLDPRILPYYDPAVERKIAVVTGGNTGIGWYTVLH-LYLHGFVVYICGRNS---HKISKAIQEILAEAKKRCHEDDDGSSPGAGPGPSIQRLG-SLHYIHLDLTDLKCVERAALKILKLEDHIDVLVNNAGIMAVPLEMTKDGFEVQLQTNYISHFIFTMRLLPLLRHCRG-RIISLSSIGHHLEFMYWKLSKT----WDYKPNMLFTWFRYAMSKTALIQCTKMLAIKYP--DVLCLSVHPGLVMNTNLFSYWTRLPIVGIFFWLLFQVVGFFFGVSNEQGSLASLKCALDPNLSVEKDNGKYFTTGGKESKSSYVSNNVDEAASTWIWTVHQLRDRGFDI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*** : : :*: : . . : * *. .: :::: .. *:: .. . . . ***: *:.*.: . : :. *: **. : * * **:* :* ::.** :. * :: *:: :** .*:: : : . . :: : * :* . : :. * .: ::*** :: : : :. *: : * * :*.: ::: ** .: .* **.. . .* ::. * : . : : ", "identical_positions": 45, "similar_positions": 96, "identity": "10.47%" }, { "cls_id": "homologset.agr.MGI:1931249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIA5-1", "uniprot_id": "S35B4_MOUSE", "id": "Q8CIA5-1", "name": "Nucleotide sugar transporter SLC35B4", "aln": "----MRPAFAVGLVFAGCCSNVIFLELLARTHPG-CGNIVTFAQFLFIAVEGFLFEANLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQTGLS---DKDGFQAF-AWWLLGIAALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVIGVT-----MPVMWFYLLMNVVTQYVCIRGVFILTTECTSLTVTLVVTLRKFVSLIFSILYFQNQFTMWHWLGTSFVFIGTLMYTEVWKNLGTTKSELQKDDKKD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAN4-1", "uniprot_id": "D3ZAN4_RAT", "id": "D3ZAN4-1", "name": "Solute carrier family 35 member B4", "aln": "----MRPAFAVGLVFAGCCSNVIFLELLARTHPG-CGNIVTFAQFLFIAVEGFLFEADLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQSSLS---DKDGFQAF-AWWLLGIGALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVLGVT-----VPIMWFYLLMNVVTQYVCIRGVFILTTECSSLTVTLVVTLRKFVSLIFSILYFQNQFTLWHWLGTVFVFTGTLMYTEVWKNLGATKSQLQKDDKKD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969S0-1", "uniprot_id": "S35B4_HUMAN", "id": "Q969S0-1", "name": "Nucleotide sugar transporter SLC35B4", "aln": "----MRPALAVGLVFAGCCSNVIFLELLARKHPG-CGNIVTFAQFLFIAVEGFLFEADLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFICTFMSAKQVTSQSSLS---ENDGFQAF-VWWLLGIGALTFALLMSARMGIFQETLYKRFGKHSKEALFYNHALPLPGFVFLASDIYDHAVLFNKSELYEIPVIGVT-----LPIMWFYLLMNIITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGTTKSEPQKDSKKN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW46-1", "uniprot_id": "S35B4_DANRE", "id": "Q7ZW46-1", "name": "UDP-xylose and UDP-N-acetylglucosamine transporter", "aln": "----MNTLFAVTLVFVGCCSNVVFLELLVRDFPG-CGNIVTFAQFAFIALEGFIFETNFGR-----KKPQIPLSNYVIMVTMFFTVSVINNYALDFNIAMPLHMIFRSGSLIANMILGIIILKNRYSMSKYLSIVLVSVGIFICTIMSAKQVNVEKGGT---EEDGVYAF-MHWLLGIAMLTFALLMSARMGIFQETLYKKYGKHSKEALFYNHCLPLPGFLLLSTNIYNHAVLFSQSPPMEVPVIGLS-----MPVMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFLSLIISILYFQNPFTAWHWVGTAVVFLGTLLYTEVLSSIPAAFKGYKVDKKAE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W429-1", "uniprot_id": "S35B4_DROME", "id": "Q9W429-1", "name": "Endoplasmic reticulum GDP-fucose transporter", "aln": "MALNLKALLGMLFVFIGCCSNVVFLELIIQIDPG-AGNLITFAQFLFIALEGLVFTSKFFT-----VRPKIALKDYVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAGIILCTLVSSGDVKDNTHHSLKVDT-SYSDF-FWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCNVVTQYVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVINQVRDAYRARSSRKTHFDTAPLAKKVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAN9-1", "uniprot_id": "Q9VAN9_DROME", "id": "Q9VAN9-1", "name": "UDP-xylose and UDP-N-acetylglucosamine transporter", "aln": "MNLSIRAISAICGVFLGCCSGVVFLELLVKLDPG-AGNLITGAQFAFIALEGFIFTSKFGL-----AQRVISLRDYALLVAMFFLTSVCNNYVFKFKVPMTLHMIIRGGSLISNMCLCTLILKRSYRLSQYISVLMISVGIFVCTYFSSPDLVGKMEN---LDSGAEADT-FWWLLGVALLVLALFVSSYMGITQELLYRRHGKCAREALYYTHLLPLPAFLLMHDDIRTHWLLAFTGESYQLPLLGVA-----VPLILLYLLGNVLAQHLCISSVYTLTTECSSLTVTLILTLRKFISLVFSIVYFRNPFTWWHWLGTALVFVGTLMFANVIRVPK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40004-1", "uniprot_id": "YEA4_YEAST", "id": "P40004-1", "name": "UDP-N-acetylglucosamine transporter YEA4", "aln": "---MWNSLKAFALVFGGCCSNVITFETLMSNETGSINNLITFCQFLFVTCQGLPEFLDVHQPFPYFKPLKTPLHVYVITVVLFYISSTTNNNVFKYNISIPIHIVFRCFGTVITMFTCWLLNGRKYTKIQILSTLFLTIGAIIASLFKDADFRYQDLKLQAWKIGSDQSVDLTFIFGICILVLSSFTSSLLSAYNERTYQKYGKHWKENIFYSHFLSLPLFLFSRKQLIHEYRVMRKSERILCSNFGGK---ILVPREETLLLFNVLTQYFCVKGVNILASKTNALTLSITLLVRKFISLLLSVRLFDNNLSYTGYIGVYLVFFGAFIYSLGSIHPRQNDKGAIKKSK------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. ** ****.*: :* : .* .*::* .** *:: :*: .. .: *.: *.:*: .. ** .:. ::.:.:*:::* . : .* :: . * : * ::: * ::.: .. :. : . . : .*: *.:: : :: :. :* *::.** * :::.* *.** *:: :: . : . . :* .* ** *:::*:.*: .* *::: :**::: : :***:**::*: * * :: ::*. .** *::::: ", "identical_positions": 61, "similar_positions": 122, "identity": "16.94%" }, { "cls_id": "homologset.agr.MGI:1931250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PA5-1", "uniprot_id": "NKG7_MOUSE", "id": "Q99PA5-1", "name": "Protein NKG7", "aln": "MEPCRSLALFAGSLGLTSSLIALTTDFWIVATGPHFSAHSGLWPTSQETQVAGYIHVTQSFCILAVLWGLVSVSFLILSCIPALSAPGRGPLVSTVMAFSAALSILVAMAVYTSMRWSQTPFSQVQTFFSWSFYLGWVSFILFLFAGCLSLGAHCRTRRAEYETL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16617-1", "uniprot_id": "NKG7_HUMAN", "id": "Q16617-1", "name": "Protein NKG7", "aln": "MELCRSLALLGGSLGLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISGYIHVTQTFSIMAVLWALVSVSFLVLSCFPSLFPPGHGPLVSTTAAFAAAISMVVAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******:.***** .****:****: *.** .*********.: ::*******:*.*:****.*******:***:*:* .**:******. **:**:*::******** **.*.*..*:************** **:* :*.******* *. ****", "identical_positions": 114, "similar_positions": 34, "identity": "69.09%" }, { "cls_id": "homologset.agr.MGI:1931256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70244-1", "uniprot_id": "CUBN_RAT", "id": "O70244-1", "name": "Cubilin", "aln": "---MSSQFLWGFVTLLMIAELDGKTGKPEQRGQKRIADLHQPRMTTEEGNLVFLTSSTQNIEFRTGSLGKIKLNDE-------------------------------DLGECLHQIQRNKDDIIDLRKNTTGLPQNILSQVHQLNSKLVDLERDFQNLQQNVERKVCSSNPCLNGGTCVNLHDSFVCICPSQWKGLFCSEDVNECVVYSGTPFG-CQSGSTCVNTVGSFRCDCTPDTYGPQCASKYNDCEQG-SKQLC-KHGICEDLQRVHHGQPNFHCICDAGWTTPPN------GISCTEDKDECSLQPSPCSEH--AQCFNTQGSFYCGACPKGWQGNGYECQDINECEIN-NGGCSQAPLVPCLNTPGSFSCGNCPAGFSGDGRVCT------------PVDICSIHNGGCHPEATCSSSPVLGSFLPVCTCPPGYTGNGYGSNGCVR-LSNIC-SRHPCVNG--QCIETVSSYFCKCDSGWSGQNCTENINDCSSNPCLNGGTCIDGING--FTCDCTSSWTGYYCQTPQAACGGILSGTQGTFAYHSPNDT--YIHNVNCFWIVRTDEEKVLHVTFTFFDLESASNCPREYLQIHDGDSSADFPLGRYCGSRPPQG---IHSSANALYFHLYSEYIRSGRGFTARWEAKLPECGG-ILTDN--YGSITSPGYPGNYPPGRDCVWQVLVNPNSLITFTFGTLSLESHNDCSKDYLEIRDGPFHQDPVLGKFCTSLSTPPLKTTGPAARIHFHSDSETSDKGFHITYLTTQSDLDCGGNYTDTDGELLLPPLSGPFSHSRQCVYLITQAQGEQIVINFTHVELESQMGCSHTYIEVGD----HDSLLRKICG---NETLFPIRSVSNKVWIRLRIDAL--VQKASFRADYQVACGGMLRGE-GFFRSPFYPNAYPGRRTCRWTISQPQRQVVLLNFTDFQIGSSAS-CDTDYIEIGPSSV-----LGSPGNEKFCSSNIP-SFITSVYNILYVTFVKSSSMENRGFTAKFSSDK---LECGEVLTASTGIIESPGHPNVYPRGVNCTWHVVVQRGQLIRLEFSSFYLEFHYNCTNDYLEIYDT-------AAQTFLGRYCGKSIPPSLTSNSNSIKLIFVSDSALAHEGFSINYEAIDASSVCLYDYTDNFGMLSSPNFPNNYPSNWECIYRITVGLNQQIALHFTDFTLEDY--FGSQCVDFVEIRDGGYETSPLVGIYCGSVLPPTIISHSNKLWLKFKSDAALTAKGFSAYWDGSSTGCGGNLTTPTGVLTSPNYPMPYYHSSECYWRLEASHGSPFELEFQDFHLEHHPSCSLDYLAVFDGPTTNSRLIDKLCG---DTTPAPIRSNKDVVLLKLRT-DAGQQGRGFEINFRQRCDNVVIVNKTSGILESINYPNPYDKNQ--RCNWTIQAT-TGNTVNYTFLGFDVESYM-NCSTDYVELYDGPQ----WMGRYCGNNMPPPGATTGSQLHVLFHTDGINSGEKGFKMQWFTHGCGGEMSGTAGSFSSPGYPNSYPHNKECIWNIRVAPGSSIQLTIHDFDVEY--HTSCNYDSLEIYAGLDFNSPRIAQLCSQSPSANPMQVSSTGNELAIRFKTDSTLNGRGFNASWRAVPGGCGGIIQLSRGEIHSPNYP--------NNYRANTECSWIIQVERHHRVLLNITDFDLEAPDSC----LRLMDGSSSTN--ARVASVCGRQQPPNSIIASG-NSLFVRFRSGSSSQNRGFRAEFREECGGRIMTDSSD-TIFSPLYPHNYLHNQNCSWIIEAQPPFNHITLSFTHFQLQNS--------TDCTRDFVEILDGNDYDAPVQGRYCGFSLPHPIISFGNALTVRFVTDSTRSFEGFRAIYSASTSSCGGSFYTLDGIFNSPDYPADYHPNAECVWNIASSPGNRLQLSFLSFNLENSLNCNKDFVEIREGNATGHLIGRYCGNSLPGNYSSAEGHSLWVRFVSDGSGTGMGFQARFKNIFGNNNIVGTHGKIASPFWPGKYPYNSNYKWVVNVDAYHIIHGRILEM-DIEPTTNCFYDSLKIYDGFDTHSRLIGTYCG-TQTESFSSSRNSLTFQFSSDSSVSGRGFLLEWFAVDVSDSTPPTIAPGACGGFMVTGDTPVHIFSPGWPREYANGADCIWIIYAPD----STVELNILSLDIEPQQSCNYDKLIVKDG-DSDLSPELAVLCGVSPPGPIRSTG--EYMYIRFTSDTSVAGTGFNASFHKSCGGYLHADRGVITSPKYPDTYL-PNLNCSWHVLVQTGLTIAVHFEQPFQIQNRDSFCSQG-DYLVLRNGPDNHSPPLGPSGRNGRFCGMYAPSTLFTSGNEMFVQFISDSSNGGQGFKIRYEAKSL-ACGGTVYIHDADSDGYLTSPNYPANYPQHAECIWILEAPPGRSIQLQFEDQFNIEDTPN----CSVSYLELRDGANSNARLVSKLCGHTLPHSWVSSRERIYLKFHTDGGSSYMGFKAKYSIASCGGTVSGDSGVIESIGYPTLPYANN----VFCQWFIRGLPGHYLTLSFEDFNLQSSPG---CTKDFVEIWENHTSGRVLGRYCGNSTPSS--------VDTSSNVASVKFVTDGSVT-ASGFRLQFKSSRQVCGGDLHGPTGTFTSPNYPNPNPHARICEWTITVQEGRRIVLTFTNLR---LSTQPSCNSEHLIVFNGIRSNSPLLQKLCSRVNVTN--EFKSSGNTMKVVFFTDGSRPYGGFTASYTSTEDAVCG------GFLPSVSGGNFSSPGYNGIRDYARNLDCEWTLSNPNRENSSISIYFLELSIESHQDCTFDVLEFRVGDADGPLIEKFCSLSAPTAPLVIPYPQVWIHFVSNERVEYTGFYIEYSFTDCGGIRTGDNGVISSPNYPN-------------LYSAWTHCSWLLKAPEGHTITLTFSDFLLEAHP----------TCTSDSVTVRNGDSPGSPVIGRYCGQSVPRPIQSGSNQLIVTFNTNNQGQTRGFYATWTTNALGCGGTFHSANGTIKSPHWP-QTFPENSRCSWTVITHESKHWEISFDSNFRIPSSDSQCQNSFVKVWEGRLMINKTLLATSCGDVAPSPIVTSGNIFTAVFQSE-EMAAQGFSASFISRCG--RTFNTSPGDIISPNFPKQYDNNMNCTYLIDADPQSLVILTFVSFHLEDRSAITGTCDHDGLHIIKGRNLSSTPLVTICGSETLRPLTVDGPVLLNFYSDAYTTDFGFKISYRAITCGGIYNESSGILRSPSYSYSNYPNNLYCVYSLHVRSSRVIIIRFNDFDVAPSNLCAHDFLEVFDGPSIGNRS-LGKFCG--STRPQTVKSTNSSLTLLFKTDSSQTARGWKIFFRETIGPQQGCGGYLTEDNQSFVSPDSDSNGRYDKGLSCIWYIVAPENKLVKLTFNVFTLEGPSSAGSCVYDYVQIADGASINSYLGGKFCG------SRMPAPFISSGNFLTFQFVSDVTVEMR--GFNATYTFVDMPCGGTYNATSTPQNASSPHLSNIGRP------YSTCTWVIAAPPQQQVQITVWDLQLP--SQDCSQSYLELQDSV-----QTGGNRVTQFCGANYTTLPVFYSS-MSTAVVVFKSGVLN-RNSQVQFSYQIADCNREYNQTFGNLKSPGWPQNYD---------NNLDCTIILRAPQNHSISLFFYWFQLEDSRQCMNDFLEVRNGGSSTSPLLDKYCSNLLPNPVFSQSNELYLHFHSDHSVTNNGYEIIWTSSAAG--CGGTLLGDEGI---FTNPGFPDSYPNNTHCEWTIVAPSGRPVSVGFPFLSIDSSGGCDQNYLIVFNGPDANSPPFGPLCGINTGIAPFYASSNRVFIRFHAEYTTRLSGFEIMWSS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLB4-1", "uniprot_id": "CUBN_MOUSE", "id": "Q9JLB4-1", "name": "Cubilin", "aln": "---MASHFLWGFVTLLMVPGLDGETGTPEQKLQKRIADLHQPRMTTEEGNLVFLTSSAQNIEFRTGSLGKIKLNDD-------------------------------DLGECLHQIQRNKDDIIDLKRNTTGLPQNILSQVHQLNSKLVDLERDFQSLQQNVERKVCSSNPCHNGGTCVNLHDSFICICPSQWKGLFCSEDVNECVLYAGTPFG-CQSGSTCVNTMGSFRCDCTPDTYGPQCASKYNDCEQG-SQQLC-KHGICEDLQRVYHGQLRFNCICDAGWTTLPN------GISCTEDKDECSLQPSPCSEH--AQCFNTQGSFYCGACPKGWQGNGYQCQDINECEIN-NGGCSQAPLVPCLNTPGSFTCGNCPAGFSGDGRVCT------------PLDICSIHNGGCHPDATCSSSSVLGSLLPVCTCPPGYTGNGYGSNGCVR-LSNMC-SRHPCVNG--QCIETVSSYFCKCDSGWFGQNCTENINECVSNPCLNGGTCIDGVNG--FTCDCTSSWTGYYCQTPQAACGGILSGTQGTFAYQSPNDT--YVHNVNCFWVVRTDEEKVLHITFTFFDLESASNCPREYLQIHDGDSSADFPLGRYCGSTPPQG---VHSSANSLYFHLYSEYIKRGRGFTARWEAKLPECGG-ILTGN--YGSITSPGYPGNYPPGRDCVWNLLVSPGSLITFTFGTLSLESHNDCSKDYLEIRDGPFHHDPILGKFCTSLSTPPLQTTGPAARIHFHSDSETSDKGFHITYLTTPSDLYCGGNYTDTEGELLLPPLTGPFSHSRQCVYLISQPQGEQIVINFTHVELESQRGCSHTFIEVGD----HESLLRKICG---NETLFPIRSISNNVWIRLRIDAL--VQKASFRADYQVACGGELRGE-GVIRSPFYPNAYAGRRTCRWTISQPPREVVLLNFTDFQIGSSSS-CDTDYIEIGPSSV-----LGSPGNEKFCGTNIP-SFITSVYNVLYVTFVKSSSMENRGFMAMFSSEK---LECGKVLTESTGIIESPGHPNVYPSGVNCTWHIVVQRGQLIRLVFSSFYLEFHYNCANDYLEVYDT-------IAQTSLGRYCGKSIPPSLTSSSHSIKLIFVSDSALAHEGFSINYEAINASSVCLYDYTDNFGRLSSPNFPNNYPHNWNCVYRITVGLNQQIALHFTDFALEDY--FGPKCVDFVEIRDGGFETSPLIGIYCGSVFPPRIISHSNKLWLRFKSDTALTARGFSAYWDASSTGCGGNLTTPTGVLTSPNYPMPYYHSSECYWRLEASRGSPFLLEFQDFHLEHHPNCSLDYLAVFDGPSTNSRLINKLCG---DTPPAPIRSSKDIVLLKLRT-DAGQQGRGFEINYRQTCDNVVIVNKTSGILESINYPNPYDKDQ--RCNWTIQAT-TGNTVNYTFLEFDVENYV-NCSTDYLELYDGPQ----RIGRYCGENIPPPGATTGSKLIVVFHTDGVDSGEKGFKMHWFIHGCGGEMSGTMGSFSSPGYPNSYPHNKECIWNIRVAPGNSIQLTIHDFDVEY--HASCKYDTLEIYTGLDFHSPRIAQLCSRSPSANPMQISSTDNELAIRFKTDSSLNGRGFNASWRAVPGGCGGIFQVSRGEIHSPNYP--------NNYRANTECSWIIQVEKYHRVLLNITDFDLEATDSC----LMTYDGSSSAN--TRVATVCGRQQPPNSITSSG-NSLFVRFQSGSSSQSRGFRAQFRQECGAHIITDSSD-SISSPLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHLQSS--------TDCTRDFVEILDGRDSDAPVQGRYCGTSLPHPIISFGNALTVRFVSDSVYGFDGFHAIYSASTSACGGTFYTGDGIFNSPGYPEDYHSNTECVWNIASSPGNHLQLSFLSFQLENSLNCNKDFVEIREGNATGHLMGRYCGNSLPGNYSSIEGHNLWVRFVSDGSGTGMGFQARFKNIFGNDNIVGTHGKIATPFWPGNYPLNSNYRWTVNVDSSHIIHGRILEM-DIELTTNCFYDSLKIYDGFDIHSRLIGTYCG-TQRESFSSSRNSLTFQFSSDSSKSGRGFLLEWFAVDVSNVTLPTIAPGACGGYMVTGDTPVFFFSPGWPGPYGNGADCIWIIYAPD----STVELNILSMDIEAQLSCSYDKLIIKDG-DSRLSQQLAVLCGRSVPGPIRSTG--EYMYIRFTSDGSVTGAGFNASFQKSCGGYLHADRGIITSPKYPDNYL-PNLNCSWHVLVQSGLTIAVHFEQPFQIQNRDSSCSQG-DYLVLRNGPDNHSPPLGPSGGNGRFCGIYTPSTLFTSDNEMFIQFISDNSNGGQGFKIRYEAKSL-ACGGTIYIHDANSDGYVTSPNYPANYPQHAECIWILEAPSGRSIQLQFEDQFNIEETPN----CSASYLELRDGANSNAPVLSKLCGHTLPRNWVSSRGLMYLKFHTEGGSGYMGFKAKYSIVSCGGTVSGDSGVIESVGYPTRLYANN----VFCQWHIQGLPGHYLTIRFEDFNLQSSPG---CAKDFVEIWENHTSGILLGRYCGNSIPSS--------VDTSSNVASIRFVTDGSVT-DSGFRLQFKSSREVCGGDLHGPTGTFTSPNYPNPNPHPRICEWTINVHEGRQIILTFTNLR---LSTQQSCNTEHLIVFNGIRNNSPRLQKLCSRVNVTN--EFKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG------GTLPSVSGGNFSSPGYNGIRDYARNLDCEWTLSNPNRENSSISIHFLGLSLESHQDCTFDVLEFRVGNADGPLIEKFCSLSAPRVPLVIPYPQVWIHFVSNERVEYTGFYVEYSFTNCGGIQTGENGVISSPNYPN-------------LYSRWTQCSWLLEAPEGHTITLTFSDFSVENHP----------TCTSDSVTVRNGDSPGSPIIGRYCGQSVPGPIQSGSNQLVVTFNTNNQGQSRGFYATWNTNTLGCGGTLHSDNGTIKSPHWP-QTFPENSRCSWTAVTHESKHWEISFDSNFRIPSSDSQCRNSFVKVWEGMLETNDALLATSCGNVAPSPIVTLGNIFTAVFQSE-EMPAQGFSASFISRCG--RTFNSSTGDIVSPNFPKHYDNNMNCNYYIDVAPQSLVILTFVSFHLEDRSAVSGTCDYDGLHIIKGHNLSSTPLVTICGSETLRPLTIDGPVMLNFYSDAYITDFGFKISYRVANCGGIYSGTYGVLNSPSFSYTNYPNNVYCVYSLQVRNDRLILLRFNDFEIVPSNLCSHDYLEVFDGPSIGNRS-IGKFCG--STLPQVIKSTNNSLTLLFKTDSSQTARGWKVSFRETIGPQQGCGGYLTEDSKSFVSPDHDSDGLYDKGLNCIWYIIAPENKLVKLTFNAFTLEEPSSPGKCTFDYVQIADGASINSYLGGRFCG------SSRPAPFISSGNFLTVQFVSDISIQMR--GFNATYTFVDMPCGGTYNATSMPQNTSSPQLSNIRRP------FSTCTWVIEAPPHQQVQITVWKLQLP--SQDCSRSSLELQDSE-----QTNGNQVTQFCGANYTTLPVFYSS-GSTAVVVFKSDFLN-RNSRVHFTYEIADCNREYNQAFGNLKSPGWPQGYA---------NNLDCSIILRAPQNHRISLFFYWFQLEDSRQCMNDFLEVRNGSSSSSPLLGKYCSNLLPNPIFSQSNELYLHFHSDDSDTHHGYEIIWASSPTG--CGGTLLGNEGI---LANPGFPDSYPNNTHCEWTIVAPSGRPLSVGFPFLSIDSPGGCDQNYLILFNGPDANSPPFGPFCGIDTVVAPFHASSNRVFIRFHAEYATVSSGFEIMWSS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60494-1", "uniprot_id": "CUBN_HUMAN", "id": "O60494-1", "name": "Cubilin", "aln": "MMNMSLPFLWSLLTLLIFAEVNGEAGELELQRQKRSINLQQPRMATERGNLVFLTGSAQNIEFRTGSLGKIKLNDE-------------------------------DLSECLHQIQKNKEDIIELKGSAIGLPQNISSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS-CQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGG-SVARC-VHGICEDLMREQAGEPKYSCVCDAGWMFSPN------SPACTLDRDECSFQPGPCSTL--VQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN-NGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCT------------LTDICSVSNGGCHPDASCSST--LGS-LPLCTCLPGYTGNGYGPNGCVQ-LSNIC-LSHPCLNG--QCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDS--FSCECTRLWTGALCQVPQQVCGESLSGINGSFSYRSPDVG--YVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHE---LLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGG-ILTGP--YGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRD----GETLLGKVCG---NGTISHIKSITNSVWIRFKIDAS--VEKASFRAVYQVACGDELTGE-GVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAH-CETDYVEIGSSSI-----LGSPENKKYCGTDIP-SFITSVYNFLYVTFVKSSSTENHGFMAKFSAED---LACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDT-------DSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEA--IGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCG---DEKPPLIRSSGDSMFIKLRT-DEGQQGRGFKAEYRQTCENVVIVNQTYGILESIGYPNPYSENQ--HCNWTIRAT-TGNTVNYTFLAFDLEHHI-NCSTDYLELYDGPR----QMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEY--HSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGCGGIFQAPSGEIHSPNYP--------SPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC----IMAYDGLSSTM--SRLARTCGREQLANPIVSSG-NSLFLRFQSGPSRQNRGFRAQFRQACGGHILTSSFD-TVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERS--------TTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEM-DIEEIQNCYYDKLRIYDGPSIHARLIGAYCG-TQTESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPD----STVELNILSLDIESHRTCAYDSLVIRDG-DNNLAQQLAVLCGREIPGPIRSTG--EYMFIRFTSDSSVTRAGFNASFHKSCGGYLHADRGIITSPKYPETYP-SNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG-DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSL-ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPN----CTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPTLPYRDN----LFCEWHLQGLSGHYLTISFEDFNLQNSSG---CEKDFVEIWDNHTSGNILGRYCGNTIPDS--------IDTSSNTAVVRFVTDGSVT-ASGFRLRFESSMEECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLR---LATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSN--EIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG------GSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFRVGDADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGGIQIGDSGVITSPNYPN-------------AYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHT----------TCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIRSPHWP-QNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASFVSRCG--SNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLLNFYSNEQITDFGFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTSDPL-LGKFCG--SKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCG------STVPAPFISSGNFLTVQFISDLTLERE--GFNATYTIMDMPCGGTYNATWTPQNISSPNSSDPDVP------FSICTWVIDSPPHQQVKITVWALQLT--SQDCTQNYLQLQDSP-----QGHGNSRFQFCGRNASAVPVFYSS-MSTAMVIFKSGVVN-RNSRMSFTYQIADCNRDYHKAFGNLRSPGWPDNYD---------NDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSG--CGGTLYGDRGS---FTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTWDS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PME6-1", "uniprot_id": "A0A8M9PME6_DANRE", "id": "A0A8M9PME6-1", "name": "Cubilin", "aln": "-MAQTLSFSWIFIFLLFFAGLQGDRGGQNHSRQKRAISSEQPRMISENGHLTFSAGYNKDIRFTTSGTGSLKVGAE-------------------------------DLILQINQIKKNKEDIDTIKN--SGPSEDIKNQLHLLDTRVTTLESKVQSIEQTVQRKTCSSNPCQNTGTCLNLLDAFHCLCPDNWQGPTCAVDVNECQVLAGTPLG-CQNGATCNNTPGSYTCTCTPEWYGPHCTSRYDDCAGG-SQDLC-VHGLCIDSDRVNPNEPKYKCICDAGWTSPPG------VAACTADIDECSLPTKPCSTNPPVECFNTLGSFYCGACPSGWQGNGYSCQDVDECATN-NGGCSTSPFVPCLNTMGSFHCGQCPPGYEGDGKTCT------------QADICSTNNGGCFPLATCTSTP--GSTIPLCTCPPGYVGNGYGPTGCTQ-ISDICGTSNPCVNG--QCENTATGYVCHCDPGWAGQNCDQNMNECSSNPCQNGGTCTDGING--YTCTCTAQWTGPQCQTPQQECGGILESPAGTFSYPNNPGTGDYDHQVSCAWVIRTDPNQILRITFPFFDIENSASCNFDFLQVHDGESASAFVIGKYCGSAAPAE---LFSSHNSLYFWFRSDHSVSAGGFTVAWQSQAPVCGG-QLTNT--YGDIKSPGYPGNYPPNRDCYWTVNVNPGLLITFAFGTLSLEHHDNCNFDFLEIRDGLLPEDSLLGKYCSTASPPPLQTTGPSAWIHFHSDFSISDRGFHITYTTSPSDPGCGGVFTETEGIIISPNWPNNYAHNRQCIYIIRMPRSEQVALNFTHMDLETHTGCLFDFVEVRDGTGETDPLIGKYCG---NTLPAPILSTTNGLWIRFQSDSS--VSRAGFRAMYELACGGTLSGT-GQIRTPFHPDPYPHNKVCEWVINQPEGYVVTLNFLTFDVEGSST-CAFDHVEVRDGPS-----SSSPLIGRYCGVEMP-PMLESTQKSMFIQFKTDASVSNHGFTAEFGSAE---QGCGETLTEPTGSFTSPGHPTEYPHGANCTWYISVPPGHLIRLSFSYFNMEFHTNCAYDYVDVYDNG----TALTGTLLGRFCGRSVPPSLTSTDSLMTVLLVSDSSLSAEGFSADYISINATTDCSKVFRTSTGELSSPNYPDNYPTNRECVYRIIVEVNMQIMLNFTDFQLEG---FSSCGFDYLEIRDGGYETSPLIGRYCGTNAPPIIVSHSNRLWMKFRSDHSLTYKGFQAHWDGTQTGCGGTLTTSSGGFTSPNYPLPYPANAECYWHIKTSAGSRIQLSFGDFHLEDTVDCYFDYLMVYDGNNSNAHQLAKLCG---NQIPAPISSSRENMYVKLRT-DSIIHTGGFLANYHSTCNGMLIANRSRGMIESLNYPNDYPSHA--DCSWTIQAY-MGNTINYTFIAFEVEQSD-GCGYDHVKLYDGPNDQANLIGTFCGNVPPPAGTTSGTSLHIVFRSD-MSISYRGFQMDWYQNGCGGELFGPVGTFNSPGYPGQYPMNRECVWHIHTSPGSSISITILEFDVEY--HPDCNYDKLEVYGGPDLSAPRLAQLCTTRPPSNPLQVSSTGNAVTVRFTSDAVVSGRGFNATWIEVPGGCGGSVTAPSGEIHSPQYP--------SNYPDNADCSWVITVDAGHRVFFNFTDLDIENQFSCSYDYVAIHDGPHEHS--PLLAQVCGTSRPP-PVTSST-NVIYVRFRSDHSLNHRGFSAQFSEACGSFIVTDDVGGEIASPRYPYPYPPNQDCSWIIRAQEPFNHVTLSFTDFELEMLN-------SNCTHDSVEILDGDNVQAPSVGRYCGSNLPHPVTSLSNAMVVKFVSDHAVGRKGFRATYMASTSGCGGLLNMESGAFNSPNYPDVYPPNVECVWTLTSSPGNRIQLSFIMFQLQPSSDCSNDYLEIREGHSTGALVGRFCGDSLPTNYTSITGHILWIKFFSDSSISGAGFRAVFSHLYGN-DITGSTGLIASPLYPRTYPNNADYRWTVTVDSDSHIQIQFLDI-DIEDLFNCLYDKLKIYDGPSTNSFLLGEFCGLTLPNPVRSSGSAITLEFQSDTVIGGKGFLIEWTAVQGS-GPLPTIEPGACGGTLVTGDTPQFLFSPGWPELYQHNLDCSWVIRSPS----SIVEFNLLSLDMEDEVSCLHDSLDIRDG-ETNASPLIAKVCGRQLPGSLHSTG--DAMLLRFTSDGSINGRGFNATFSRGCGGFLHTDRGVLSSPQYPQNYK-PNLNCNWQVMVTPGFRVSVTFQSPFQVQGYGNQCSTG-DYLELRNGPDGNSPTLS-----GRLCGSNVPSTFQTTDNSLYAHFVSDGSNEGNGFKLLFEAHSS-ACGGFIELNDGDPPGYITSPDYPSNYPQNIDCVWIITVPNGEAVQLDFEGDFYIEPHSG----CLFDYIEIRDGPTSDADLIGRLCGNTRPSTQHSSGTTMYLRFRTDASVTHIGFKAKYSIAVCGGTYIGQNGVIRSPGFPGSNYPDN----SNCEWYLEGPTGHYLTLTYTAFDLQSSAN---CNSDYVEIREYNASGRLLGKHCGNNLPAP--------MDTGDSFAYVKFVSDASAN-AGGFSLSFEASIEECGGDLNAPFGTISSPNYPNLYPHSRICRWSITVPQGRRVTLTINDLR---LEDQSTCAFDFVEILNGLTPSAPRLDRLCGTVPAGT--QVKSSGNTMTVIFSTDSSVSNGGFTADYSSEESAVCG------GILNEP--GNFTSPDFG-NGNYSNNLNCEWLIQNPHHTNSSIVVIIDELHLEHHQTCEWDYLEFRLGDHNGELLTRLCGQTPPSIPIVVSTPSLWVHFLSDEAVGDLGFKATYYFSECGGTQSGDGGVISSPGYPN-------------VYPSPSRCTWLLEAPVGHTVVLTFTYFEVEEHS----------QCVWDSVTIFNGASSGSPIIGQYCGHNSPGTIRSGSNKLVVVFLADHTVSKGGFAATWSTDSTGCGGIIHADTGTIKSPNYP-QNFPTNIECSWTIIAHDGNHLEMGFASDFQIPDSSGQCQNSYIKMWSDNIQNDENLLATGCGTTAPAAIIAPRNVITARFQSS-DTPGKGFSAAFYTTCG--ANFTASSGRVVSPNYPDHYPANSNCNYIINAGEQFVVVLTFRTFQIEAHS----TCVYDGVKIYSGTTASSSPLATLCGNTIPGIFTTFGPMLINFYSDSIIHDNGFLAEYTTIPCGGVFNGTAGTIGSPSHSISNYHHNINCTYHIYVRNNRVINLKFNSFNLEASSTCNFDYVAVYDGESTLAPL-MGKFCG--HELPPNLRSSTNHMFLQFVTDSSVAAEGWRATYSETLGPQQGCGGFLSSPSGMFGSPDIDMNGQYEPHMDCMWTIAVEVNKAINLTFTSFELEG-STGTLCRYDHVTIYDGDSANFPLVGTFCG------DLIPAPFISASNFLTVHFISDGTVSRR--GFNATYSTVNSLCGGAFNATATSQTITSPLYPNAYPP------FTSCRWVLDAPSQEGVKVSVQQFHLDT-SQSCTSNFLEFKDFP-----VGDYGQAHKFCSADS-HVPDFYSY-GRTMHITFKSEAFM-TGNGFSLSYQVAGCSRVYEQEYGYLKSPGWPDLYP---------HNLECSIVLQAPQNSFISLFFTSFDVETHPSCNFDYLEVRNGSTATSPLLGKHCGNTLPNPVFPGSNELFIFFKSDFTTTRNGFEITWTSSPQG--CGGVLYGDHGS---FTSPNYPGTYANGSSCEWSIRAPSGRVVTVTFNQISIDDPGDCQNNYLKLFDGPDANSPAVGPYCGLETNIAPFRASSNLVFVKFSAQSAVLPSGFRLTWSS---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W332-1", "uniprot_id": "CUBN_DROME", "id": "Q9W332-1", "name": "Cubilin homolog", "aln": "---MEGAARSRLLLCWTLLAIITDTWPIAEG------FVNSPKIISKDGNLIFESGANRNISFRLSGNSRLTINEELDVMELLLATSGSKKRSGGKDDDFVDARELADQLADFNRRAFGANGLSAMLRVQQNRTRGSMALLRRFQTRLRALENRVDRMKTDLEANSCASGPCENGGTCYNTYTGFRCQCRSAFEGTKCEMDVNECALYEGTDLG-CQNGGQCQNHFGTYSCLCQPGWHGMHCTQRKADCSQSSAWELC-GHGSCVP----SADDAGYRCICEPGWKTNGL------TPICGEDVDECSDSAAHKPCS--TSCINLPGSFTCAPCPAGLTGNGVSCRDLDECQTN-NGGCSLSPKVDCINTYGSYHCGECPVGWTGDGRKCERSPQDIDIPAGQTPRTCPAGNNPCYPTASCFLIS----GTTSCRCPMGMVGTGYGPNGCVN-GTTTNCKENPCLNGGICLFAGPSNYTCLCPIGFRPPICEPQPSPCDQHPCKNGGRCRPTTSGDLFVCQCLPGYRGRLCETRFSSCNGMLSAQSGRLRYPPEGTG--YEHNAQCAWVIRTNESLVVNVTFNSFDVEDSTECRFDWLQINDGRSAAAQIIGRYCGNHLPHGG-NIVSSGNQLYLWFRSDNSTAKEGFDLTWNSMEPQCGGRLNFET--HGTLASPGSPGNYPKNRDCRWQLVAPTTKRIKLTFFSLQLEQHANCNFDYVLIKDSISGRE--LAKYCTTGAPAPLLLPTHLAEIHFHSDAEGSDTGFQLHYSVEERVPGCGGVYTAKEGTISESSTANTEPGGVSCEYEIHLAVGEQVVIQFARLELDPLDCLEVLDITDEG----GSILQEKICG---SDASRLNPPTFTSEFNRLKIKFY--ARAGSFQLNYRMACDYKLNNEQGTITSPGYPNLTRSDRICTYTISTATNTVISLKRIDFQLTNGES-DDDDNDECLTTNLRINDGLNRKILGPYCGKNQPEENFVSETNYLQLHLSTDVDSMGRGFKFEYRALATGNDKCGGVHTRSGDHIRLPVHDDSYAGEATCYWVIMAPANKAIRLHWNSFSLENAVDCIYDYLEIYDSLGAQVNDERSKPLAKYCGNSVPEDLLSHSRQLVLKFVSDYSESDGGFDLTYTFEDR-AKCGGHIHASSGELTSPEYPANYSAGLDCDWHLTGTIDHLLEIQVENFELEQ---SPNCSADYLEVRNGGGTDSPLIGRFCGRDIPARIPGFSHEMRLILHTDSAINGRGFRLRWRIFAFGCGGSLRSNMGAISSPRYPNSYPNMAHCEWRISLHPGSGISLLIEDLELEGLSNCYYDSVKIYTGIKLPNQSPCKVLCKDDDLHNPLIQLENNKGTIVFDS-DASNTFRGFRISYKANCIRNLTAT--TGTIESLNYMEPFWETIPINCSWTIRAP-KGNRVLVEVSHLARHEQH-VPTATMPGGLYIVD----------GRNVQEIVTPQAMNISGEVLTVVHNASNVNFQLDYRIDGCMEELRGTFGFFQSPNYPKMYPNNLECYWLITVEQDSAIELTINNIDLED--SPNCTKDALTVSN----HKNSVEVHERHCGSTTKLVITSSGHRLHVRFISDNSHNGLGFEATYRTVKATCGGKLTARNGVIESPNYP--------LNYPAHSRCEWQVEVSQHHQIVFEMADLNLESGYDCNWDYLEAYDLTEDDTEGERLFKVCGDETEDDKLLSSSSNMAVVRFISDDSVSKKGFRLHFHESCGQTIIVDETMFDYIQMSRQAAR--NESCLWVFQAVEPNKRIIFTPTHVKLREDANQQYPTEGDCLNVGVKIYEGTEPQGTPRLKFCRSHPPALISNGQ----ALTVSVPLQLVEEFQGHYMTMDTSCGSIYNALSGKFTSPYYPASYPPNIECLWLLEASMGNSLSLTLESMDLEKSESCNRDYLEVREESESGQLIGVYCGNEVPGVIHSRG--AIWMKFKSDDDNVGEGFMASYNYEHHN-ELNGTEGTIESPHFPSKFQDPVPYSWRITVDKEYVVAISLLYLRDLDQPHLNFYDGYSDIGARIEVTDPDETIISSTNVVYFTSNRGPFKLNWNRLSKEALRSNRTAEERTRQCGNQLITIDRSVIG-----------FHSPGYPNGYEQDLNCFWTLVPSNPAMHAVLTLSQIDLEIFSEDCIADYVKIFSGS-DLQNWSELRTLCSLPTESSDRVFHGRPYLRVEFVTDPSVNKTGFNGIVRTACGSEITASKGLVNITEILKVLPRPNHDCVWTIKVRQGRRIKIDFPDFQLQNNMASGSSDCRNYLLLRNGNDEDSPFLG----RGKYCEDVVHEVLNTSSNKAYIKFHFASPPR-FLVSFRFEELRY-TDSGRIRLSASGDEQFISSPYYPHLPHPHSECIWIVEAPPEHRIMLHFQGAFDMLDATGEPEECQREFVLINDGSTELRPEIGRYCGNRKPDTIYSTGNQMRIRYFTDVSEPHMGFNASLSVARCGGSFHSPEGVIASPSRDLLLIHEEGKQLQECVYTIELEKGSTIDLTSEYLQIPTLRNGSCSQRNHLMLEEMDAFGLDGEEKIVDTLMLCGMEAKHLISETNKIVFRYRFLDGIPAE-NQGFRLKYTSLGSRCGETIYASVGVLQTPGYPLGVPHPMHCKWQVQVPKGRRVRLEILDFN---TGTNMDLRGRLGFRGRLTVANDFKMQSILGRYNVDPPAEVLSSDNTMGIDAFLLPIVQNHGIKLRFSAYGSSSCPGFTVMMNEVADIQFQRFNISRPLHCSYKVVPPSNSTLLIRVKEYNTTSVMMWNTHMCALLSPLKFNRLEQEEELMERILCDYQSPAPGKPLPSIRLPFPIQLVVSASARNAMTNLVLSYSTQSCGGVIILEPGDNMTVHQPSGMVSAAGAIDCAWAIGPYTDASGEDEVLVPQDIQLEVSVYNVNLPAPSPSAQSPEAPCLHHYLKVYNGPDQNSPSLGLFCNQATAVNMVVERG-LFLEYHSDSFSANATFNVSIKYGSGCGGKLVYP----YRAIDFA-EQYKNNVECIWEVEATMGYHIGLTFQGRFYIEDSPGCTKDYLLVQQRNETTGNWTDLQRICGRVAPEMINTTSPYLRLIFRSDGDVVADGFLAKFERNCGGLLYADSTEQELASPGFPNGYEKYLQCNWTIVPRSPSMGGVLVSFVNFDLEQGPISVCLYDNLTVTTKDKGKDPQQTTLCGVKHNHEYRGKEYVNLLLRTDGSYSGRGFTLLYTSRLCGGIISRTSMVESPVQHTDNTLPPGSDCYWNLTAPAGYKFNIKFLFIDFEANSNCAYDGVEVFSGPIPDERYRWGRFCGRINEDLPLISIPQERGIIHSFSDDRDPSRGFRALVRVMPNCDEKIS---LNGSSRYVYSKFNNAGGYQNDLDCQIVFRVNPDQQISVEFSNFHVQD---TDGCRSDYVELRDGGGTFADIIGRFCG------QNQPPTLRTTRHTLYMRFVTDNKVTDT--GFQVTINAIPRLCGSSEITLSADGTKEVTINSPARTPGGNYPNGVSCFWKIKGDSLLRVQFVNFDLHGPNQNGSCVDDYLKIYNSEDAPLLEQGLGTDLVFNGQTSSKNGFGFAT-EHVYCGNVKPDIYYGRSSEVYLKFRSKGLEQHGGFQLQVALNSNRERHYDGLQGRVHLSQSADCNIIIRAPPNYTLSLYYTELIFG-TYDCEMENLEVFDRTNRSLQRVCSFVD--MGKSLFSNANELRLQMKTGSYLTSLDLTYLASPVEKGPGCGGQFYNTEGI---FSNPFYPNNVRNNSECQWIVRVPSNNVVFLTFEVFNLGSKTTCHTDYLQILEQDATGEEREMRRFCGEDNPKYYKSRRSQVLVRFHKTVNYDGIGWVIRFAGVYSDHQIPRHLLGGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTP0-1", "uniprot_id": "Q9VTP0_DROME", "id": "Q9VTP0-1", "name": "", "aln": "MLIKSLKCLFLLVFCLQFPHSNTSRDNLEKR---------AHLVRQSNDNLLLEPAWDRNVSLRLMGESATVTINDVDMMTVLRRRQRIIADRQAARREPLKVDAVRDMFHDVELKMTRIQRRIFSARNSTKRSGLNQRILRRQLQRVERVKGILQTLAGNLARNECLSNPCKNGGTCHDAYKGFQCECPAGWQGDSCEDDVNECFTLAGTDLDGCLNNGQCINTPGSYRCVCRNGFTGTHCRLRHNTCLFGGSRELCGEHGTCIQ----AANSAGYVCICDQGWTWADANVTSASPSACVRDVDECEPRVNPCHDE----CINLPGSFRCGACPTGYTGDGRFCRDIDECASEDNGGCSLQPRVTCTNTEGSHRCGRCPAGWTGDGRTCT-----------ASDSNSCNNEGICHPLAKCEYVS----DMVVCTCPLGSFGHGYGADGCSADSSRLPCDQHPCQNNG-TCVQNGRGTTCICQPGYSGVVCNSS-DACHPSPCLNGGTCRLLPDAK-YQCVCPRGYTGTTCSHQRFFCGVTIRGPSGQLHYPPNTADGDYQADERCPFIIRTNRNMVLNLTFTQFQLEDSADCTADFLQLHDGNSLSSRLIGRFCGSRLPMTNGSVITTQEQVFFWFRSDNQTQGKGFHVIWNSLPFSCGETINLTSTQTGVLRSPGYPGQARPELDCRWQLTAPFGYRLLLRFYDISLGSSEASAGNCSQDSLIVYDSDRQLLRACQSIQPPPVYSSSNSLRLDFHTDAIRSDSSFQMHYEVVPGHPGCGGVYTESRGRISG------YMNFEVCLYLIEQPRGTQVKLVIDRVSLVQSLSCHYLKIEIFDGRSTDAPLLRRICGSHEESELEPIISIGNVILVRYEYALSGVRLSKSFDLTYTRVCTGNFNTNSGIISTPNYPGPYFDDMTCTYNLTGPLDTAVRMRITDLSLGTANNENDTSYLDVYLSAD----------QKRHIVKSTDNLILLSHSNRASLVFHGSG--GGRGMRLEYNFVP---NQCGGFLNEPGRRYVTAVR------GTFCQWFIDFP---------GRKKISIHTLGPTPSISIYDN---------STSPGKLVNSYSGSVGDVFDGDLLTINLHTNWPRLEIYSIQFDIVQQ-DSCGGTFTARFGYIKSPNWPKNYGESQMCEWILRAPFGHRIELVVHNFTLEEEYSSTGCWTDWLEIRNGDSESSPLIGRYCGNEIPSRIPSFGNVLHLKFKSDDSMEEKGFLLSWQQMGAGCGGKLSSSMGTIHSPHLLAGNRGILACDWQIIVAEGSRVSLQLR----SNDNRICSGQLTLYDGPTTASNPIVIRCN---GTIAKPLQSTGNRVLVRYDVGHDAPDGTDFMLNYQTNCR--VRLEGLQGAIETPNFPENYPPGQ--DCEWDIRAGGRKNHLQLIFSHLSVEKFSSICLNDYVSLVDMLDDQTLSEQHLCTNDGLEPITTVGNRLLLRFKSD-SSVELQGFRAEYKRIGCGEHLRESGGRFESPNAP--FSVDMDCVWIITASEGNQIRLLLHEVYFEAPQIECRDAESSLSVSAPSGYNSSVVLFRSCHEETQTQTFTSPGNELVIRFVSSSAPSRKYFKASFVQVPASCGGYISASSGVLTTPGFHNHQDSKNVANYTSNIECVWTVEVTNGYGIRPHFEQFNLTDSGNCSVSFVELTKLEPDNKE-IFLEKTCGEDSPMIRIVHGR--KLRVRFKSQAGTWGR-FIMYFERQCGGRLSTGEGY---------LQSRLDEECSWLVTSPEG-SKLSLIINQLECPKCN-------AVSQNCSEGLQLLNDDDQVLLYQMCRDHPANLIVPANN---VRILTHGIR----LQAQFSTFENSCGGNITSASGSLSSPNYPDSYPANIECVWSIRTRPGNALEITFEAMDIVRSEHCNDDFLEIR-SSVQGPLLALYCDKNLP-ETPLVVHSELWIKFRSRPGNTAGGFRFRWTYVHNNEINSGINGTIEPPPPLFVSNEDQPFTWRLFTDFKKVFVLQFEEY----------ISGLILFDGYDDNALAVNIPVS---PWRFTSSSNVVYLKTVNDALTHFR-LKWGVLDSNLVASNLSLTTGGCTKELTLSHHGDIELSSPGYPHGYAPNLNCEWTIRSQFP--SHHIYAHSIIVDLEDYPACSADYLSIQSSRDLIKWKNELHACKASQIAPVHGTP---YLRLQFRSDVSINGTGFRAKLRTSCG---SNMTGIVGTIPQENLFD----ECAWHIDVRPGRKIDIAIN-----YNNMPPIAVCEAYGLIYDGVDEHASLLEHTRFGNQMG--IRRTQFRTSGSHAYIKYHIGRSRINGLCLWNLTYREFNECNGEIQLNQQAPNYTIMSPGYPYLPHPHAECTWLVMAPPGETIAVDFDEQFELSARHCD-----KENVEFFDGATKLARLLLRTCRKPQ-NTVRTTGNLLLVHYQSQLNEPTGGFRLNLSLSTCGGQFSASAGFISSENYPHLGGYPKP---SVCEYSILLPKNAFIRLNITDLHLPYDANG--TSSDRLEIVDYEDRTQKLMVLDGRTKTSIL-------FTLNTNAATIRFVAVQNVNNYRGFKIRYERYVGTCSRDINGASGDIVIPPMPQS-VWLRFCRLRISVPKGQRVRLNLLNLSNIRVVKRNDTNRSFMQIGRLESMAHFSFYNDANSLSKIAEFRIDGGYNGSGIIESTDNYMLVVVMTNQLDLSATPLRAR----YSSSEPTVCPPNIGDQATGSISIQSLLQVPGYHCTIKFVGTDSATLTFKVEEYLFQTAGGPAVVFRDDITNIPVKAMYANVTNSFVSVVTSAGSVTLLNSKN--VKLRRFRATYRRHNCGGRLQAAEG--VTIESPD-------------LLTTLNDAYGEVECLWTLSNSNGYVLEGNVTLT---------DRCDREYIVIFSGQSE----VGRICRGMAMNSTLLERPFSTILYHSESRLAQQSKFILQAWKSVSSGNAIRIDHRPSPPVTISSKNYLESKQRIWEFVTNDGLSLRLHFLERIFIVSSPNCSTDRLTVERYDQTTEEYIEVTSLCGRQAANDILVPSARMRVIFQTNSNITGDGFSFQVIPSCDSVLLAGAEIQTLASPSWAAFRGRQFNCSYTFYAHDNHQVVVSVRTRGRPWASYACSRSYFEAYRRGDGNGVGEESIGRLCP---EFEVKGNGRVRLRYVSP---LSRWFEMQYQLIQCGGNYSTSFTLRPPQNEDSSVYAHNTLCEWRITAPPQHAVVIEFKYFDMESSRNCGFDSLTIYRGHVVSEEQRTGLLCG-NVTNPETIIVNSNEALIVLTTDSSNSYRGFLASVRFTPNCNEHVALDLEVPRMSVMRQYVVN---ISESLLCIFQASAPPDYRISLEVRKLQLADDVVCRTCS--YLEIHDSKDVEGQNLGRYYGGTNGNEPSNRTKVFSSFSDMSFKLIATTGQAQKNISFELILQMVRTVCGQGEYDLRLNETITLGMQYDNSTRFYEG--SIQCLWIIKNKGDVELEFRKLRLKEISQGTGKCTDYLKLSKPY----------FSRSYCGQHDKSFKIVEEVNESNLQLAFHSDGLEESQGFEVIIRRKSTCNRNYTELSQVIDTSN----------------LTNCTDYIRVPRGYSITLYVMTVLFDSFDNNYFRVIDVQ----SNKTIFTNSDIQWETKAMITSTNELRLESRQ---VSSLKFFYFSTSNQFPGGCGGDLAVGGSVGSYLENPSYEG--RNSSLCTWKISVPAGGSLRFSFAEFNMGSESNCDLDNVRFYDSVVDDQRLVKAICG-SRIPDMFTIAKNNVIIVAKKSQNFDGLGFRMDIIEIG-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . : . .:* : .. ::: : . . : * .. : . : :: :: .: : : : * *.** * *** : .* * * ::* * ***** ** :. * ... * * *:: * * * :* : * . : * ** * .. : *:*: ** * * ***. *:* *** *..** * *:* *.*::** : ***** * * * ** ** * ** *: ***: * . :. *.* *.* * * * * ***. ** : :** *. . * * *: * . . * ** *** * .. : * * : * *. *. : . * : * * : * ::::*: ::.:** * :*. .* ::**: ** * : :*::**. * : :: : ::: : *: ** *:: ** * : *** **: ** * : . : : * :.* . : : * : * : .*: . :.**:* ** .*:: * . *** :* * : * * : . . *: : : ::.* : . * : ** . . . * . .* * .* : * : :* .*. * : : . .: :. :.: . . : . . : * : : : . .:*: : ** . . . : * * : :. :.:**. . .: . . : : : : . * * :.**::* ** . * : : . : : . :* ** *::*:*:*. ***:* : * *. * ...: : : :::* ** * ****.* : * : **. * * : ** . * : . . : :: * . . . : : : . .* .:: * : * :*: .: : : *.* *:* * : . : . :. . : . : . .*: .: ** .: . * *.**. * :. : :* * * . .. * : : :. .* : : .:*..: : :** :. . *:*:: * . *** . * : :* : * : * * : * : : .: :::: .* : . . : .** . : . :** * . : * * . ** : ... ::.* *:. : .:: : .... . . : . : : * . : :: :: : ..**. .* :.** ** * .* **:* : : ** :.::: ::: * *. *::*:* * *:. :*....* :*::* * . . ** : . * * * : .* : * : .: . : . .. : . . *. . . :. : : . : ***:* * :* * : . : : ::: . .. : * .. : : :.* :* *: **.. . .** *:: . :* * : * * : : : . * : :* * :. * .: : *:.. : :: . .* : : : ** :* : :* *:: .* : :.*: * : . : : ** . : : * . :: : ::: :: . **. . *: *** . *.: * . : * : : . : : :.: . : : : : . . . :*: . ** : : *. : .. * : * * *. : . :*::: * : :: . . : . .. .. * : :. . . . : .: . : . : : . . . : : : . : * .*** * : *. . . : . * . : : .* . :* * : : :: : * . . . : : . . * : . : * : * .. . : . : : ** *. : . : *::. : ..** . *. : **.:. :*.: : : . . . : . :* : : : . * * *** . : . . * : : . . :.* ::. .. * .* : :: * * :** : . : :*. . .*: . :: . . : * . : : : . : : * :: : *. . * : * . . :: : .:::: .*: : ** . * * : ::. :: . . . *:: . : . .:. . : . .: ... :*. : .* . ::*: . . . ::* . . . :.::. *** : : : :. *** : . : .* : . *.: * * : .*:. : . * :.:.. * : : . : .. . : . *:: .: : ", "identical_positions": 435, "similar_positions": 802, "identity": "11.19%" }, { "cls_id": "homologset.agr.MGI:1931271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRD7-1", "uniprot_id": "D3ZRD7_RAT", "id": "D3ZRD7-1", "name": "Olfactory receptor", "aln": "-----------------MAAENHSTVTEFILGGLTHRPELQLPLFLLFLGIYTVTMVGNLGMITLIGLNTQLHTPMYFFLSNLSLVDLCYSSVITPKMLINFVSQRNLISYVGCMSQLYFFLVFVIAECYMLTVMAYDRYVAICHPLLYNIIMSPALCSLLVAFVYAMGLIGSTIETGLMLKLNYCEVLISHYFCDILPLMKLSCSSTYDVEMAVFFLAGFNIVVTSLTVLISYAFILSSILRISSTEGRSKAFSTCSSHFAAVGLFYGSTAFMYLKPSTASSLAQENVASVFYTTVIPMLNPLIYSLRNKEVKAALDKTLKRKLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VGE3-1", "uniprot_id": "Q8VGE3_MOUSE", "id": "Q8VGE3-1", "name": "Olfactory receptor", "aln": "-----------------MAAENQSTVTEFILRGLTNRPELQLPLLLLFLGIYIITMVGNLGMITLIGLNSQLHTPMYFFLSNLSLVDLCYSSVITPKMLINFVSQRNLISYVGCMSQLYFFLVFVIAECYMLTVMAYDRYVAICQPLLYNIIMSPALCSLLVVFVYAMGLIGSTIETSLMLKLNYCEDLISHYFCDILPLMKLSCSSTYDIEMAVFFLAGFNIIVTSLTVLISYAFILSSILRISSNEGRSKAFSTCSSHFAAVGLFYGSTAFMYLKPSTASSLAQENVASVFYTTVIPMLNPLIYSLRNKEVKTALDKTLRRRVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGG7-1", "uniprot_id": "OR8A1_HUMAN", "id": "Q8NGG7-1", "name": "Olfactory receptor 8A1", "aln": "MGFLSPMHPCRPPTQRRMAAGNHSTVTEFILKGLTKRADLQLPLFLLFLGIYLVTIVGNLGMITLICLNSQLHTPMYYFLSNLSLMDLCYSSVITPKMLVNFVSEKNIISYAGCMSQLYFFLVFVIAECYMLTVMAYDRYVAICHPLLYNIIMSHHTCLLLVAVVYAIGLIGSTIETGLMLKLPYCEHLISHYFCDILPLMKLSCSSTYDVEMTVFFSAGFNIIVTSLTVLVSYTFILSSILGISTTEGRSKAFSTCSSHLAAVGMFYGSTAFMYLKPSTISSLTQENVASVFYTTVIPMLNPLIYSLRNKEVKAAVQKTLRGKLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** *:******** ***:*.:*****:******* :*:********** **:*******:*******:*************:****::*:***.********************************:********* * ***..***:*********.***** *** **********************:**:*** *****:*******:**:******* **:.*************:****:************** ***:*****************************:*::***: ::*", "identical_positions": 259, "similar_positions": 36, "identity": "79.45%" }, { "cls_id": "homologset.agr.MGI:1931295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P74-1", "uniprot_id": "RB27B_RAT", "id": "Q99P74-1", "name": "Ras-related protein Rab-27B", "aln": "----------------------------MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLLDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEK-------TQ---VPDTVNGVNSGKVDGEKPAEKKCAC------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P58-1", "uniprot_id": "RB27B_MOUSE", "id": "Q99P58-1", "name": "Ras-related protein Rab-27B", "aln": "----------------------------MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEK-------TQ---VPDTVNGGNSGKLDGEKPAEKKCAC------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00194-1", "uniprot_id": "RB27B_HUMAN", "id": "O00194-1", "name": "Ras-related protein Rab-27B", "aln": "----------------------------MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEK-------TQ---IPDTVNGGNSGNLDGEKPPEKKCIC------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T9E2-1", "uniprot_id": "A0AB32T9E2_DANRE", "id": "A0AB32T9E2-1", "name": "small monomeric GTPase", "aln": "MRTGVVFYGLTHIRNKSKNTPGFSSSSTMTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYTTNSPNGTTGKTFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLVGNKADLADQREVQEKQAKELADKYGIPYFETSAATGSEVDKAVVTLLDLVMKRMEQCVEK-------PS---ADANTSDGSS-KLSAAPAQQKKCAC------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76901-1", "uniprot_id": "O76901_DROME", "id": "O76901-1", "name": "", "aln": "-----------------MRAAPPEPEPLQLAGSGE---QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSR------GRRHRIHLQIWDTAGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFSLLLTQSRCLPNIAYGQPEDLVRLHDRREEPCSRRNCRNC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : ::*.********* :**:***.:*:.:**:**********::* :. *: .::***:****************:********:*****::***:. **:***:::**.*:**:** ***.** : * *.. *. *. :* :**:****.** :*.::* *:. :*:*:*:.. : .. . . . : :: * ", "identical_positions": 103, "similar_positions": 66, "identity": "39.31%" }, { "cls_id": "homologset.agr.MGI:1931307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E7F6V3-1", "uniprot_id": "E7F6V3_DANRE", "id": "E7F6V3-1", "name": "", "aln": "---METLKRWM-KDWKYPTSLLFIYGFFSTVKPLEPFLYPFLTGPDKNLTTEQLNNQIFPVWTYSYLAVLVPVFLLTDWLRYKPVVVFQSLILFCTTSMLLWCNGVPEMQAMQFTYGVVTSCDVAYFTYIYSMVEIKHYLKATSYCRTAHLLGYTVGSVLGQILVSLELMSYNNILVFTLVLTGIAMIASILLPMPKVSMFFHKKQSEEDDNEGHSGNVKPLEPEEGFGTMVDLSNDVKVDETK-------WQQDVLDGSNGCDSSSAKSSKSSRKAGCGDVLLRLWRDFLQCFSSRTLLLWSAWWALATCGYNQTVNYVQSLWEHVEPSSNFTVYNGGAEALSNLFGAAAAYGIGLSSAD--WSRWGEMALSALSALEGGALFAMVFSGNIWVCYGGYILFKSLYMLLITIAMFQIAAGLNMERYALVFGANTFCALVLQTIITSVVVDSRG-LGVDVVTQFIINGAYFSVIAVIFFLRGLY--TTMCRKPET---------------------DTSRE----------NLEEAFKKDAQ---------------IVTETKL----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LV16-1", "uniprot_id": "Q1LV16_DANRE", "id": "Q1LV16-1", "name": "", "aln": "------MRR---SDWVFPTVLLSLYGFFANCRPAEPFLTPYLVGP-KNISEEVVTNYLFPIWTYSYLSLLCPVFLLTDLLRYKPLIVAQGLFLVTNYIILSFANSLPALTYLQFNFAVVTSTEVAYFSYIYSVIPPERYQRATGYVRSAMLAGYTFGAILGQMLISLANTSYFHVNTVTLSLMIVALCISLSLPMPQHGVFFKKKQVEVS---------------------MDTMNEVADGGS---------SRDLEKEVTGRSVKICEYIKTSGKQ--------MWESLKESYSSRRLVQWSLWWALATAGYGQVFNYVQLMWDHIEPSSTSSVYNGGVEAVCALVGAAAAFSVGYIQVQ--WGVWGELSLGVFSAVGAGCVFLMGLTNSIWLSYAGYAIFKASYMFLITITMFQIAVNLSMECYALTFGINSFVALTLQTILTAIVVDNTA-LGLDIATQGLYTVCKHFCTSTVTNTEALT--VIMEDQRKS---------------------DTSGKQETQSSSSSSSLQNKEQSALQ---------------AYTETAL----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0L0X6-1", "uniprot_id": "A0ABK0L0X6_RAT", "id": "A0ABK0L0X6-1", "name": "", "aln": "MVAMNCCRTPPRDSWVYPTVILCLFGFFSMFRPSESFLIPFLSGPSKNLTSTEMTNEILPVWTYSYLAMLPPVFVLTDYLRYKPIIMLHVMAFTICYLFLLFGQSVMLMQTAEFFFGIVSATEIAYFAYIYSMVSPEHYQKVSSYCRSITLVSYTAGSVLAQLLVSLMNVPYSTLFYISLACVSVAFFVSLFLPMPKKSMFFHTKPNREA-----------------CPKPLEPCTVLKEAHN--------NGAQPELFANAQNLGDREQ-----DNSALRIFVYWFQDLKECYSSKHLVYWSLWWAFATAGYNQILNFVQVLWEQKAPSKDSSIYNGAVEAIATFGGALASFSVGYIKVD--WDLLGELGLAVFSAVVAGSLLLMNYTLSIWVCYTGYVLVKSSYSFLITIAVFQIAVNLSLERYALVFGIDTFIALVIQTIMTMIVADQRG-LQLPVTTQLSAERKCRTLLPPRALVSHTYKSQEMCQRSSNPVTSTPVTKGQDFKMGSQKSFATHRHPIRTDSKTTTKLHPQANRPAHCKHSIYDHGSYISYFLDAMTKYLTRNNSREELKCFSSQFGGMHSITKEKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PL8-1", "uniprot_id": "S19A3_MOUSE", "id": "Q99PL8-1", "name": "Thiamine transporter 2", "aln": "--MDSSCRTPPSNSWVYPTVILCLFGFFSMFRPSEAFLIPFLSEPSKNLTSPEMTNEILPVWTYSYLATLPPVFVLTDYLRYKPVIMLHVVAFATSYLFLLFGQGVMLMQTAEFFFGVVSATEIAYFAYIYSMVSPEHYQKVSSYCRSITLVAYTAGSVLAQLLVSLTNLPYSSLFYISLACVSVAFFFSLFLPMPKKSMFFHAKSDRDD-----------------CPKPLEQCTVPKEAQS--------NRTHSELFANSKNLEDREMSNPDPENSALRHFAHWFQDLKECYSSKHLVYWSLWWAFATAGYNQILNYVQVLWEHKAPSQDSSIYNGAVEAIATFGGALASFSVGYLKVN--WDLLGELGLAVFSAVIAGSLFLMNYSRSIWVCYAGYLLVKSSYSFLITIAVFQIAVNLSLERYALVFGIDTFIALVIQTIMTMIVVDQRG-LQLPVTTQFLVYGSYFAVIAGVFLMRSIY---ILCS-------------------------AKCRKEVQNLATTRSPNEPHPQEPS-----------------NVSTKF----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZV2-1", "uniprot_id": "S19A3_HUMAN", "id": "Q9BZV2-1", "name": "Thiamine transporter 2", "aln": "---MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVFVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVVSPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSRE------------------IKKSSSVNPVLEETHEGEAPGCEEQKPTSEILSTSGKLNKGQLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVN--WDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVDQRG-LNLPVSIQFLVYGSYFAVIAGIFLMRSMY---ITYS-------------------------TKSQKDVQSPAPSENPDVSHPEEESN---------------IIMSTKL----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGV6-1", "uniprot_id": "Q9VGV6_DROME", "id": "Q9VGV6-1", "name": "Thiamine transporter 1", "aln": "-----------MESWLKISCLLCIFGFLRELRPSEPYHAEILMGEWYHVTQDEVNRSVYPVGTYSYLALLIFVFLITDLLRYKPVIIANATTGICIWGTLIWTTTLSGLQAVEVFYGFYQAGEVAYYSYIYAKVDKQYYPRVTSHTRAAMFVGKLVAGILAQMVIGMRWMNYKQLFYITVTSQVAALLWAFFLPKVEKSLYFHNRSEAIEG------------------------------------------GTKSDGGNLEKGSEQPSNEEASQEKKIPALQLLWSHFRSAYTNPLVIQWSLWYAISLAGFLQITTYMQVVWKSFENEP-TIAWNGAVDVALTLLSAVFALLAGYFHAGRLNTRSSLLSMALLSVLEGGCVLLSCWTDDIYLSYLGYVLYGGLFAFTITVASSELASSLEEDSFALVFGFNTFVGLLLQCILTFVVVSEKANLNLNVFQQFSVYAFYFIVIGIVYSIAVIL------------------------------------QYIWSISKKPKAIQEAN-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGV5-1", "uniprot_id": "Q9VGV5_DROME", "id": "Q9VGV5-1", "name": "Thiamine transporter 1", "aln": "-----------MKEWLKISCLLCVFGCIREIRPSEPYVTEYLLGPWRNITEQQLTHDVYPVGTYSYLVQLVFVFLITDFLRYKPLIITIGAAGVIIWSMLIWTTSLLSLQILEFFFGTYMAAEVAYYTYIYAKVDKKYYARVTSHTRAAMFAGKLVSGITSQLMLNLELMNYKELNYITLGTQIIAMLWAFGLPRVDRSLYFHREQLSITE------------------------------------------PQTQLPG-VGNLAEMDQQQENTQ-KQPGALSLLWLHFRNAYTNPRVVQWSLWYAIGLAGYLQVTYYVQVLWKVIEPEP-VIAWNGAVDAVLTALAALSALAAGYLHTGRLRPRASLLILGILSAVEGGCVLICCWTQDIYWSYAGFVLFGALYGFTITVASAEVARNLEEESFGLVFGVNTFVALIFQSLLTIIFVTDTG-FELDPVGQYTAYAFYFIGVGVLYLISVLI------------------------------------EYLMCRNNDVEKLENSLD------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK64-1", "uniprot_id": "Q9VK64_DROME", "id": "Q9VK64-1", "name": "Thiamine transporter 1", "aln": "-----------MKSWLKISLLLCTFGFFREFRPSEPYVTEYLASDYGNLTTDQIYQDVYPFGTYSVLAQLVIVFLITDLVRYKPVIVLSALAGITLFSMLIWTETVGMLQVAQVFFGTFTAAEVAYYTYMYAKVNKEQYQVVTGHTRAAILSGKFLGGLFAQILVSTDSMDYRQLHYLSLATQLISLAVSLFLPSVPRSLYFYAGSEKIT---------------------------------------------------IADGEETSPKFSFAN-----ACRLLWYHLVSSYSNPVVLQWSIWWALATCGQVQVISYIQFLWKEVAPNK-LSVYNGGVEAVATLLGAIGAILAGLLNSNKRRG-SYMMGISICAAALGALLIYAAKTQLIWVAYVNYVLFCTVFFFIITVAGAVVAENLVEDSFGLIFGINTLVGLILQTILTVAVVERVG-FALEPRDQYVVYGSYFVVLGGISIIGSIC------------------------------------VKLFCRTNK-SSVENVVSLT----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* : :* :* : :* *.: * ::: : . : *. *** * * **::** :****::: * : : : :. :. : ::**::*:*: : : * .:.: *: : . ..: .*:::. * : .:: :: :: ** .::* . . : : ..::. :. ** *:*:. .* * ::* :*. . :**..:. .* : * : : :. .. :: : *: .* .: : : : **:: :* .* : :.* ** ::: .* :* ::* .. . : : * ", "identical_positions": 57, "similar_positions": 126, "identity": "9.64%" }, { "cls_id": "homologset.agr.MGI:1931321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA41-1", "uniprot_id": "D4AA41_RAT", "id": "D4AA41-1", "name": "", "aln": "MAAPLRPVPPQP---APRRS-------------PPTAPLGHDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKSALFSVLSEIKGKTAVSVQ-TQEEDPPDAQLLRLDNMLLAEGVSRPEKRGRGGAAAGS-TATPGGCP----NDNSIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLREQSRVRPVSSGEIEHMVSTIHSKFSAIQRQLKQSTCEAVMTLRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEETKEELARKGGITVSQVSNWFGNKRIRYKKNTGKFQEEATMYTGKTST-VTKTRVSGGQTSCQSTPSPDSCGPFPLTSGSDMVLTLRTLAFLQPPPGGVCLQPLAHGSWQRATTSQPSSSPAGDSGSFNSDASD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NE9-1", "uniprot_id": "PBX4_MOUSE", "id": "Q99NE9-1", "name": "Pre-B-cell leukemia transcription factor 4", "aln": "MAAPLRPVPPQP---APRRL-------------PTTAPLGHDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKSALFSVLCEIKGKTAVSIQ-FQEEDPPDAQLLRLDNMLLAEGVSRPEKRGRG-AAAGS-TATPGGCP----NDNSIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLREQSRVRPVSCREMEHMVNTIQSKFSAIQRQLKQSTCEAVMTLRSRFLDARRKRRNFSKQATDVLNEYFYSHLSNPYPSEETKEELARKGGITVSQVSNWFGNKRIRYKKNTGKFQEEATMYTGKAST-VTKARRPRGQSSCQSTPSPGPCGPLPLTNGSDVVLTLRTLAFLQPPTGGVCLQPLVHSNWQRAAP-QPASSPAGESGSFNWDAASN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYU1-1", "uniprot_id": "PBX4_HUMAN", "id": "Q9BYU1-1", "name": "Pre-B-cell leukemia transcription factor 4", "aln": "MAAPPRPAPSPP---APRR---------------------LDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCP----NDNSIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLASLQPPPGGGCLQSQAQGSWQGATPQPATASPAGDPGSINSSTSN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40427-1", "uniprot_id": "EXD_DROME", "id": "P40427-1", "name": "Homeobox protein extradenticle", "aln": "MEDPNRMLAHTGGMMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAA--------GASPYSMAGPPSGTTTPMMSP----------------APPQDSMGYPMGSGGYDQQQP--YDNSMGGYDPNLHQDLSP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * . **: * .::*****:*::***********:*******.******.*** **.:*:: *:*:***.**:******:****. *** * * *.* : :*: **. **:**********:*******.*********.****** ***:**** **:: *:*:** *: ***:** *********** ****:**************:::*********.*******:******* *:*:***************** ** ****.:*:.* :. . . : *.... *: . .*. . . ..:: . * .* .:: . : ", "identical_positions": 206, "similar_positions": 75, "identity": "51.12%" }, { "cls_id": "homologset.agr.MGI:1931322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFG6-1", "uniprot_id": "B5DFG6_RAT", "id": "B5DFG6-1", "name": "Carbonic anhydrase", "aln": "MARLSWGYDEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDS--SLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTG-SYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHN--PQLQKITDILDSIKEKGKQTRFTN-FDPLC-LLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAF------LLSNHRPPQPLKGRRVRASFY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6N1-1", "uniprot_id": "CAH13_MOUSE", "id": "Q9D6N1-1", "name": "Carbonic anhydrase 13", "aln": "MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDS--SLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTG-NYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHN--PQLQKITDILDSIKEKGKQTRFTN-FDPLC-LLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAF------LLSNHRPPQPLKGRRVRASFY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1Q1-1", "uniprot_id": "CAH13_HUMAN", "id": "Q8N1Q1-1", "name": "Carbonic anhydrase 13", "aln": "MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDS--SLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTG-SYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPN--SQLQKITDTLDSIKEKGKQTRFTN-FDLLS-LLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAF------LVSNHRPPQPLKGRKVRASFH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92051-1", "uniprot_id": "CAHZ_DANRE", "id": "Q92051-1", "name": "Carbonic anhydrase", "aln": "MA-HAWGYGPADGPESWAESFPIANGPRQSPIDIVPTQAQHDP--SLKHLKLKYDPATTKSILNNGHSFQVDFVDDDNSSTLAGGPITG-IYRLRQFHFHWGSSDDKGSEHTIAGTKFPCELHLVHWNT-KYPNFGEAASKPDGLAVVGVFLKIGAAN--PRLQKVLDALDDIKSKGRQTTFAN-FDPKT-LLPASLDYWTYEGSLTTPPLLESVTWIVLKEPISVSPAQMAKFRSLLFSSEGETPCC------MVDNYRPPQPLKGRKVRASFK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V396-1", "uniprot_id": "Q9V396_DROME", "id": "Q9V396-1", "name": "Carbonic anhydrase", "aln": "MS-HHWGYTEENGPAHWAKEYPQASGHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNPGYCWRVDVNGAD--SELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWNTTKYKSFGEAAAAPDGLAVLGVFLKAGNHH--AELDKVTSLLQFVLHKGDRVTLPQGCDPGQ-LLPDVHTYWTYEGSLTTPPCSESVIWIVFKTPIEVSDDQLNAMRNLNAYDVKEECPCNEFNGKVINNFRPPLPLGKRELREIGGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3C8-1", "uniprot_id": "Q9W3C8_DROME", "id": "Q9W3C8-1", "name": "", "aln": "-------------------------MPVQSPIEISNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQDMYVFEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNS-KYKDFTEAKNKPDGLAVVAFFIQACGEKDCPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWIIYRTPIYVSRGQVQVFRNLQSCPKDESKKIVNNYREIQRPHKDPEIFFARNTNPKSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***::* : . :: * . : * * . * . . . : **.: : :.*.* **. *. *.** : * :. * * **:*: ** .* ** .*****:..*:: : ..:.*: . : : . : . * *:** ****..* *** **: : ** :* *: :*.* * : .: * : *. . ", "identical_positions": 59, "similar_positions": 61, "identity": "21.38%" }, { "cls_id": "homologset.agr.MGI:1931324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V9Y8-1", "uniprot_id": "Q9V9Y8_DROME", "id": "Q9V9Y8-1", "name": "Carbonic anhydrase", "aln": "MQPNAFHKLLLLL---------PLAYQ----HTSNDHKDESHWDYETNGQNWGGICSTGE-----RQSPISLNVQKSL-IVPLPRIVFGNYDVKLRGPLTLLNNGHTAHVEIPETANGNK-----PFITGGLLKG-RFVAEAFHFHWGSPSSR-GSEHSINQQRFDVEMHIVHRNEKYGDIDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSKVMSALPRVTKYNAKTTIPGGLSLGQMLGNVN-PRDFFTYRGSLTTPLCEQSVTWTVFSQVLPVPYSSVSKFWK------LRDSEGHRLINNFRDIQPRNGRPVFYRIGKDLSGAYLGK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4LHX0-1", "uniprot_id": "A0A0B4LHX0_DROME", "id": "A0A0B4LHX0-1", "name": "Carbonic anhydrase", "aln": "MQAIAFHKLLLLL---------PLAFY----QSTNG----MEWNYLKNGKDWEDLCSSGK-----HQSPILLDSRTAR-KWVLPGITFWHYYRLLKRPFYIRNNGHSISLDIPVTSNGRK-----PFITGGRLKG-RYYADGLHFHWGSYKSR-GSEHLINKRRFDAEIHIVHRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIEDSNATVFGQSSLDQLIGGVS-HRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWL------LRDHWGHRLINNYRIVQDLNNRTVFY--KKRMS----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9Y6-1", "uniprot_id": "Q9V9Y6_DROME", "id": "Q9V9Y6-1", "name": "Carbonic anhydrase", "aln": "MFSIGFCWLLAICGCTFAYIEIPEAYLTAIRQDRADEQAAGEYNYDEQGDDWTGTCQSGE-----NQSPIDLIFEDSK-IVAIPRLRFNNYDQPLQTPLVITNNGHTANMVIPQTRGGQR-----PSINGSLLPG-NFEAQSVHFHWGSREAK-GSEHAINFQRYDVEMHIVHKNTIYETMGEATMHPDGLAVLGVMFRAVDRQTSQHYGLNKIFNQLPRIVQYNSNATITGRLTVGQLLGNIV-TGEFFTYNGSLTTPDCAEAVTWTVFPDVLDYPRRQITKLWN------LRDSRQRPLINNYRSIQDTNSRDVYY---RTIQ----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IMV4-1", "uniprot_id": "Q8IMV4_DROME", "id": "Q8IMV4-1", "name": "Carbonic anhydrase", "aln": "MFLVARSFAPINSG----------------TRSHFG------FNYDKQGRDWN--VKCGE-----RQSPIALWSCNAI-TCNVPKLKFLNYHKSLCDPLSVINNGLTVLMRIPKTVDGSR-----PSLCISTEGQQVFEADQLHFHWGSALSK-GSEHCLDGNYYDGEVHIVHKNASYKSNKEAGLQPNGFAVLALFIRNLEDPNIETPAMNMICKQVSSITKLDDSCPLEDSMALQDLFASID-SQKYFTYQGSLTTPPCAEAVIWFVFPTPLDVPKELWKHFWQ------LRDSRDQRVLNTYRELQDGHDRPVYR---SKAK----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB76-1", "uniprot_id": "Q9VB76_DROME", "id": "Q9VB76-1", "name": "Carbonic anhydrase", "aln": "MKLTAFLEASFLLIC---------------WSQAVSSHVFGYSEPNQRRWARHHGHCAGK-----TQSPIAITTSRTT-AIHMPAVDMIGYHNLLPYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRGAKLPG-EFEVEGLHFHWGDKNNR-GSEHVINDIRYTMEMHIVHRNKKYATIGEALNHPDGAAVLGFFFNLDEDEG---AGLVTINRHLHLIADANQEATLNVTFSLSSLIAGVD-VDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFRQ------LSDTQDGALVDNFRTLQPVGNRRIFARTGHVRHTSIATLKHEGEYLKYDWFY---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZBQ6-1", "uniprot_id": "D3ZBQ6_RAT", "id": "D3ZBQ6-1", "name": "carbonic anhydrase", "aln": "MWALGFRLCFLLM--------------LAAQVDSNGTWCYDSQDPKCGPAHWKELAPACG---GPTQSPVNIDLRLVQRDYALKPFIFHGYDSAPQDPWILENDGHTVLLRVHSCQQNCP------AIRGAGLPSSEYRLLQLHFHWGSPGHK-GSEHSVDEKHGSMEMHMVHMNTKYQSMGHARSQPDGLAILAVLLVEEDKDN---TNFSAIVSGLKNVSSPGVSVNLTSTFALASLLPSALGLLRYYRYSGSLTTPGCEPAVLWTVFENTVPIGHAQVVQFQA-VPQTGPPGLHPRPLTDNFRPQQPLGGRRISASPGASIRSS-VPIRPCLHLALLGLGVGLRLWQGP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N23-1", "uniprot_id": "CAH15_MOUSE", "id": "Q99N23-1", "name": "Carbonic anhydrase 15", "aln": "MWALDFLLSFLLIQ-------------LAAQVDSSGTWCYDSQDPKCGPAHWKELAPACG---GPTQSPINIDLRLVQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCP------AIRGAGLPSPEYRLLQLHFHWGSPGHQ-GSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDRDN---TNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVLWTVFENTVPIGHAQVVQFQA-VLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS-VSTLPCLHLALVGLGVGLRLWQGP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GKG2-1", "uniprot_id": "A0AC58GKG2_DANRE", "id": "A0AC58GKG2-1", "name": "Carbonic anhydrase", "aln": "---MVMMILMLMMS-------------VLLLARTDDDFCYD--EDHCDPYAWGDSYPSCHPLLDSHHSPINLDHHLMK-NHSLDSLQLHGFNLTHKGQWWLTNQGHSVVLEVGDGMQ----------VSGGGLPAT-YRTFQLHFHWGSVSSN-GSEHTLDHLRFPMEMHIVNIKSTHPNLTSALEDPTGIAVLGVFVDVTYLHN---ENFQSISSALSYVAYKGQTKSIKP-FPLVNLLPQNN-LTQYYRYHGSLTTPPCSEVVLWTIYEVPVYISWAQFEQFVSGIYSTEEEAEIQALLHDNYRHIHPTYSRPVYASKDAKLLTNGVSSLACFNSVSVIVYLLLKI-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH26-1", "uniprot_id": "Q9VH26_DROME", "id": "Q9VH26-1", "name": "Carbonic anhydrase", "aln": "MHLIALSLIVCCSVS--------------FSWANEWGYPDLDNNQDEPFPKWGGLCDSGK-----KQSPINLHVKGAL-KGEFDALKFENYDEHQKN-LRMVNNGHSIQLSGFDHELTLS--------GGALLQD--FVVEQIHMHWWS-------EHTINDIRYPLEVHIVHRNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAVDDLVPSVE---NYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKE------IEYDEGKQLHNNYRELQSENNRAVVLVEQPEQRSGSAGLTASVSLGLMTLILAGQKFLL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PP60-1", "uniprot_id": "A0A8M1PP60_DANRE", "id": "A0A8M1PP60-1", "name": "Carbonic anhydrase", "aln": "-----------------------------MVCSVSGSISWCYHSPSCSEVTWPIIAEKHCN--GTQQSPINIVTANVKANANLTSFTYVGYN-DSTALTVIKNTGTSIQVTLDPKKMR---------VAGGNLPG-RFASTEFHLHWGNGSAMPGSEHTVNGKRFPMELHIVNKP--------VSNTSDSLAVLGVFIEASNETGKP-ESWKTLTSYLTRIVKAGDKASLFRNFSMDDLLSGVD-RTKYYRYLGSLTTPNCNEGVIWTVFKDPIRVSRDLIDLFST--TVYINNSSNSPLMTNIFRSVQPVNGRIVMSQVAGTKTPGLLNPTSIAANLSPSLMYPILSLTFLYCVLAFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :**: : . . : : * * : : . : .*:** . ** :: *:*:*: . . .::..: : . : .: .:. :: * ****** * * * : : : . :* : .* : ", "identical_positions": 24, "similar_positions": 46, "identity": "6.69%" }, { "cls_id": "homologset.agr.MGI:1931352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BSM7-1", "uniprot_id": "LAT3_MOUSE", "id": "Q8BSM7-1", "name": "Large neutral amino acids transporter small subunit 3", "aln": "---MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCPAENRTNTTQDEQHQWTSCDQQEKMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVPFTVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQKSPSLEEGADAFISSPDIPGTSEETPEKSVPFRKS----LCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFIVTGGKERETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDAPTEGTLNENASFGDARDGASTKFTRP-RYRKVQKLTNAINAFTLTNILLVGFGIACLIKN-LHLQLLAFVLHTIVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLLLSFLGFLLPSYLYYYRSRLQREY----ATNLVDPQKVLNTSKVAT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AC62-1", "uniprot_id": "A0A8I6AC62_RAT", "id": "A0A8I6AC62-1", "name": "", "aln": "---MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCPAENRTNTTQDEQ-QWISCDQQEEMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVSFMVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQKTPSLEEGTDGFISSSDIPGTSEKTPEKSVPFRKS----LCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFLVTGGKECETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDDPTEGTLNESASFGDARDGTITKFTKP-RYRKIQKLTNAINAFTLTNILLVGFGITCLIKN-LHLQLVAFVLHTVVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLILSLLGFLLPSYLYYYRSRLEREY----ATNLLDPQKVLNTSKVAT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75387-1", "uniprot_id": "LAT3_HUMAN", "id": "O75387-1", "name": "Large neutral amino acids transporter small subunit 3", "aln": "---MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQDEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTLMALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAITFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLALDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKS----LCSPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFGAMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTV-----LGDARDGVATKSIRP-RYCKIQKLTNAISAFTLTNLLLVGFGITCLINN-LHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLTGLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQEY----AANGMGPLKVLSGSEVTA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F2Z4V7-1", "uniprot_id": "F2Z4V7_DANRE", "id": "F2Z4V7-1", "name": "", "aln": "MKGMAPSLEQAFRRRWWMAVTAVLENLLCSAVLLGWGSLLIMLKREGFYSHLCTENKTVNATGEED-KWLSCVEQEEMLNLGFTIGSFLLSAATLPLGILMDRFGPRPLRLTGSACFALSCVMMSVSAYQPEVLSAIIFLALSFNGFGGICLTFTSLTLPNMFGSLSSTVMSLMIGSYASSAVTFPGVKLIYDAGVSFTLIMWMWAGLAGLVFLNCFFNWPEKGFATPEEIETKK----MHEAENHKLT--------------------PAEEAT----GETKKPALPQETQTASVPFRRS----VFSPIFLWSLITMGMTQLRIIFFMGAMNKMLEFMVTHGDPHPSEELQYTAKKNVSFYSSIFGTLQLLCLVTCPLIGYIMDWKMKECEVD-------------QAVDGEKRAVAVPKRDGKIQKLTNAMRAFIFTNILLILFGILSLINN-LPLQILTFILHTMVRGFIHSCCGGMYAAVYPSNHFGTLTGLQSMISAVVALLQQPLFMIMVGPLNGDAFWINLGLLIFSFTGFLLPGYLFYHRRQLQIQAKGKTSTHTPDENQALTNGHSNGHVPQEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04991-1", "uniprot_id": "FMP42_YEAST", "id": "Q04991-1", "name": "Protein FMP42", "aln": "-------MTSTRTLRYAQVACACIWCLFSAGIIFGFAALKPILISEGVYHELCDPKDGD---------RLLCTAQDLKLNFIFALSATVTNIMALPVGKILDMYGPRVCGIIG-SCLLFLASGNFISAKHLVSLWDPYLVGYTLLAVAGPFVFISCFQLANSFPQRSGTVLALLTGSFDSSSALFLLYRLLYQNWFPTLNVSRFFTLYLIVPVFILACQLTIMPHSSYKTVNHIAKIAVEGLDENGRLIEGDTGSGIIPDEQERQSLIAIEREEDSIPSRPQRRKSVLETYVEDKLQKKSGGIFGVLHGKSAYEQIKSPWFYLMLLFALVAMLRINYFIATVR--TQEEYLLNDPDLALKLNSIFDMLLPLGGAVSIPFIGLLLDH-------------------------------------------TDTLSTLTILFTTSTAIGVFGLIPNSFTWNLIGIVLLVVYRPFYYTVVSDYSSKVFGFDTFGTVYGLLSCICGIFNMSQNLLDKWTHTTFNMNPFPINLTLVILTVV--FSLTLTFYIRSQILPKP--------VNERGLSSNYQTI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: *: . * : *: :.:::*:.:* :* **.* * :. * *: **: *::.: : . :**:* ::* :*** : * :*: . ::: . * ::. :: ...* : ::.: *.* * . .*.::*: **: **: * :*:*: .. : :: : .: : . ..: : :: : :: .: . : .: : . : :. :. * ::* : *: :: ::.* : : : * . : * :: *:** ::* *::: :: : :*: ** * : ::: ::* .: * * :: .. : *: : ***: ** * *..:. : *: * .:: :.* :** *::::. : :* * :: : . . . ", "identical_positions": 72, "similar_positions": 165, "identity": "12.35%" }, { "cls_id": "homologset.agr.MGI:1931415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAA6-1", "uniprot_id": "A0A0G2KAA6_RAT", "id": "A0A0G2KAA6-1", "name": "Myoneurin", "aln": "MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFG--AIYRSTSENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAFIASPS-------------------STEISSITG--------------NIELNQQTCLLTLRDYNNREK--------SEVSTDSVQAN-------------PKQRVLTKKSSQSKKKKKAFN------SQNPGR----------AKALQHHSGVSESASVELFLDANKLSPPAVEQVIQGND--------------------------TSELELTSVVENTFPAQDIVQTVTVK------RKRRKSQSHCALKEHSMSNIASVKSP-------------------------------------------------YELENAGEELDPRYS-----------------KAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVRTHTGERPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGER--PFICELCGNSYTDIKNLKKHKTKVHSG-------------TDKNADCSVDDHAVSEQDSIQRSPLSETLDVKPSDMTLPLALPLGTEDHHMLLPVTDS-------QSPTSDTLLRSTVNGYSEP--------QLIFLQQLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MD8-1", "uniprot_id": "MYNN_MOUSE", "id": "Q99MD8-1", "name": "Myoneurin", "aln": "MQYSHHCEHLLERLNKQREAGFLCDCTVVIGEFQFKAHRNVLASFSEYFG--AIYRSTSENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAFIASPS-------------------STEISSITG--------------NIELNQQACLLTLRDYNNREK--------SEVSTDSVQAN-------------PKPRALTKKSSQSKKKKKAFS------SQKPGQ----------SKAVQYPSDVLESASVELFLETSKLSSPVVEQIIQGND--------------------------SSELELTSVVENTFPTQDIVQTVTVK------RKRRKSQSHCALKEHSMSNIASVKSP-------------------------------------------------YELENAGEELDARFS-----------------KAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVRTHTGERPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGER--PFICELCGNSYTDIKNLKKHKTKVHSG-------------TDKNPDCSVDDHAVSEQDSVQRSPLSETLDVKPSDMTLPLALPLGTEDHQMLLPVTDS-------QSPASDTLLRSTVNGYSEP--------QLIFLQQLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPC7-1", "uniprot_id": "MYNN_HUMAN", "id": "Q9NPC7-1", "name": "Myoneurin", "aln": "MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFG--AIYRSTSENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAFIANPS-------------------STEISSITG--------------NIELNQQTCLLTLRDYNNREK--------SEVSTDLIQAN-------------PKQGALAKKSSQTKKKKKAFN------SPKTGQ----------NKTVQYPSDILENASVELFLDANKLPTPVVEQVAQIND--------------------------NSELELTSVVENTFPAQDIVHTVTVK------RKRGKSQPNCALKEHSMSNIASVKSP-------------------------------------------------YEAENSGEELDQRYS-----------------KAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGER--PFICELCGNSYTDIKNLKKHKTKVHSG-------------ADKTLDSSAEDHTLSEQDSIQKSPLSETMDVKPSDMTLPLALPLGTEDHHMLLPVTDT-------QSPTSDTLLRSTVNGYSEP--------QLIFLQQLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVR6-1", "uniprot_id": "MYNN_DANRE", "id": "Q7ZVR6-1", "name": "Myoneurin", "aln": "MPHITHSEFLLEQLKRQRERSFLCDCTVSIGQAQYRAHHNVLAAFSEYFSTQSVDAGREDPTITLDPESVSSAIFEKLLTYIYTGDLNMDREEIESVQKAASYLGMPEVVARCTLSQDNIKNVGSPMRQAEYEDPRSPLSPDDYEPLEPISEVEERELLREDRAGDDLVSMDEAQSSSEQTPQRVGKRGRKPKTRLYEDEFEVETISAQRGRGRGRGRPRGRPRVRPLSSDSTDQSPAHQAMSPNGSSTSRGSGRPRGRPRVRPLSTANEDPRNVEDDPAANKDQEVEKGNEEQKKETGEKDDGKNDTDNPEEVTAFKRGRGRPRIKPVSTEDQTTNSENVTTNAEDGSEPAKTKDSEGTGRKRGRPRSKPVSSEDPESVISVEISGEEAGEETSQDAEKHTEEGTEDSESNPGNSVRISKRKRILSRKLKESQAGDEEEEEEEEMDDEFENDNEDWAGEEEVKPVQDKHRPICNICGNLFSEMSSLRRHMRIHKGLKPYQCTLCTRSFRQGNQLKTHMRIHTGEKPFTCTSCDSRFAQKCQLVYHCRMHHGEEKPYKCEFCGAAFATSSNLKIHIRKHSGEKPYECGECGKRFTQASTLMYHKRRHTGEKPYICDTCGMAFAVSSSLIAHNRKHTGVTPYICLDCGKPCLTAGELRKHMDVHNDIYSLKKHSILKHNVVPELETTQTSKTDPTQCPLNIPIDHQGLIARVRSALVDSQDHEIQMEPPLPILPPETSLTIQQSAEPQMIIQHADGSEPSMIFQHAEASEAPMLIQHGEPGEQVSYVVEQYEIPATAEMEHTQIVIVQTID", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *.*.***:*::*** .******: **: *::**:****:*****. :: . .: .: ** ..*.: *:*** :**** **:* :::.:::**.** : ***::*.:. ::: :..* **.: .:: *.:. * : .:* : .*...: :.*: *: *:..*:: . ::*:. * .*: .: : .: :..:.: :..* :: : :* .:* : *. : * ::* .....* *** :.:.: . .*.. * *: * * *: **:* .:. * :*:** **::*** ************:*** * ** ::* * ******:* ****:*:.* **. ********:*.************:.*. ********** ********* *..**:**:***** ** *********:***** *********:*.***** .**** ***. :::***.**: *.. . * * .:::. :. **. . :. . :** :. : .: * . :: :: * . : . .: *:: ::: * .. : .*: *. * *::::* : ", "identical_positions": 239, "similar_positions": 204, "identity": "29.51%" }, { "cls_id": "homologset.agr.MGI:1931437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70158-1", "uniprot_id": "ASM3A_MOUSE", "id": "P70158-1", "name": "Cyclic GMP-AMP phosphodiesterase SMPDL3A", "aln": "----------------------MALLG-NFLCCLLVAWLCGPGLGVPLAPADR-------------------------------------APAVGQFWHVTDLHLDPTYHITDDRTKVCASSK---------GANASNPGPFGDVL--CDSPYQLILSAFDFIKN-SGQEASFMIWTGDSPPH--VPVPELSTGTVIKVITNMTMTVQNLFPN----------LQVFPALGNHDYWPQDQLPIVTSKVYSAVADLWKPWLGEEAISTLKKGGFYSQKVASNPGLRIISLNTNLYYG--------------------------PNIMTLNKTDPANQFEWLENTLNSSLWNKEKVYIIAHVPVG-----------------------------YLPYATDTPAIRQYYNEKLLDIFRRYSSVIAG-------------QFYGHTHRDSLMVLSDKNG-------NPLNSVFVAPAVTPVKGVLQKETNNPGVRLFQYKPGDYTLLDMVQYYLNLTEANLK-------GESNWTLEYVLTQAYSVADLQPKSLYALVQQFATKDSKQFLKYYHYYFVSYDSSATCDQHCKTLQVCAIMNLDSMSYDDCLKQHL----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q641Z7-1", "uniprot_id": "ASM3A_RAT", "id": "Q641Z7-1", "name": "Cyclic GMP-AMP phosphodiesterase SMPDL3A", "aln": "----------------------MALPG-NFLCCLLVAWLCDPGLGVPLAPAYG-------------------------------------APAVGQFWHVTDLHLDPTYHITDDHTKVCASSK---------GANVSNPGPFGDVL--CDSPYQLILSAFDFIKN-SGQEASFMIWTGDSPPH--VPVRELSTGSVIEVITNMTVTVQNLFPN----------LQVFPALGNHDYWPQDQLPIATSKVYSAVSDLWKPWLDEEAISTLRKGGFYSQKVASNPDLRIISLNTNLYYG--------------------------PNIMTLNKTDPANQFEWLENTLNSSLRNKEKVYVIAHVPVG-----------------------------YLPYATKTPAMRQYYNEKLVDIFRRYSSVIAG-------------QFYGHTHRDSLMVLSDKNG-------NPINSVFVAPAVTPVKGVLEKETNNPGVRLFQYKPGDYTLLDMLQYYLNLTEANLK-------GESNWTLEYTLTQAYGVADLQPKSLHGLAQQLATIDSKQFLKYYHYFFVSYDSSAPCDQRCKTLQICAIMNLDLVSYEDCLKRHL----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92484-1", "uniprot_id": "ASM3A_HUMAN", "id": "Q92484-1", "name": "Cyclic GMP-AMP phosphodiesterase SMPDL3A", "aln": "----------------------MALVR-ALVCCLLTAWHCRSGLGLPVAPAGGR----------------------------------NPPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSK---------GANASNPGPFGDVL--CDSPYQLILSAFDFIKN-SGQEASFMIWTGDSPPH--VPVPELSTDTVINVITNMTTTIQSLFPN----------LQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYG--------------------------PNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVG-----------------------------YLPSSQNITAMREYYNEKLIDIFQKYSDVIAG-------------QFYGHTHRDSIMVLSDKKG-------SPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLK-------GESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADCLKQLYIKHNY-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHJ3-1", "uniprot_id": "A0A8M2BHJ3_DANRE", "id": "A0A8M2BHJ3-1", "name": "Acid sphingomyelinase-like phosphodiesterase", "aln": "----------------------MALFVLLFLFCHVFNLQVSS---APVSNVFK------------------------------------HLQTASKFWHISDLHLDPTYHVTEDHTKVCFSSK---------GVPALDPGVFGDFL--CDSPYQLILSAFSYMKQ-VDLQPEFIIWTGDSPPH--VPKEELSTDVVINVIANMTRTIQQFFPQ----------IPVYPALGNHDYWPQDQFPTSENAIYDAVAKLWSPWLNPAAVATLQKGGFYSLVIK--PGLRLLSLNTNLYYS--------------------------PNEVTVNMSDPAGQFQWLQETLELSRQSMEKVYVIAHVPIG-----------------------------YLPFAKNTTAMRENYNEQLVKIFRNYSEVVEG-------------QFYGHTHRDSIMVLLDQQG-------KPVNSIFVTPAVTPIKSQIEPFSNNPGVRAYLYQPDSYTLLDIWQFYLNLTEANLE-------QRSGWKLEYIMTEAFGIDDIQPGSLQELALRFEKPQSKAFDKYFSNFMVSYNISARCEGDCKTVQVCAVHYLDRESYSQCIDKRQKD--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQD3-1", "uniprot_id": "Q8IQD3_DROME", "id": "Q8IQD3-1", "name": "", "aln": "---------------------------------MLLAPISWLGFLLAYSGLPG------------------------------------AQARIGYFWHISDLHLDTLYSTQGDIYRSCWELARSVSGSNANSAASEPPGPFGHYN--CDSPWRLIESAVKTMKAKQGDNVEFVLWTGDALSH--SAQP-LSEQKQHEILRNITELLGRSFSS----------QFIFPVLGHED----------GSGSYRRLGELWRHWLPSEALVTFDQGGYYSIEQT-KSRLRIVALNTNFMRLDPDPDPRASLSLRWPAEYFAEPKASVSSISAEDELLAEQQWLWLEEVLTKSKEKQETVYIVGHMPPGVD-------------------------ERHLGTQHNQLTFTERNNQRYLDMVRRFAPVIQG-------------QFFGHLHSDTFRLIYDAKG-------NPISWLMIAPSIVPRKAGIGSS-NNPALRLYKFDTGSGQVLDYTQFWLDLPLANRA-------NEPTWQPEYNLTHYYALPEISAVALHNFAERFTGTDLSWFTRYHRANAVRYHSGSACPGLCMLNHYCAITRLDYDEFRICLEKEQLALQGRAPAALMPTSWSWLLGVLAVFYGLHAERWSGGCNNCHIQRI------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04119-1", "uniprot_id": "PPN1_YEAST", "id": "Q04119-1", "name": "Endopolyphosphatase", "aln": "MVVVGKSEVRNVSMSRPKKKSLIAILSTCVLFFLVFIIGAKFQYVSVFSKFLDDRGDNESLQLLNDIEFTRLGLTPREPVIIKDVKTGKERKLHGRFLHITDIHPDPYYVEGSSIDAVCHTGKP--------SKKKDVAPKFGKAMSGCDSPVILMEETLRWIKENLRDKIDFVIWTGDNIRHDNDRKHPRTEAQIFDMNNIVADKMTELFSAGNEEDPRDFDVSVIPSLGNNDVFPHNMFALGPTLQTREYYRIWKNFVPQQQQRTFDRSASFLTEVIP-GKLAVLSINTLYLFKAN----------------------PLVDNCNSKKEPGYQLLLWFGYVLEELRSRGMKVWLSGHVPPIAKNFDQSCYDKFTLWTHEYRDIIIGGLYGHMNIDHFIPTDGKKARKSLLKAMEQSTRVQQGEDSNEEDEETELNRILDHAMAAKEVFLMGAKPSNKEAYMNTVRDTYYRKVWNKLERVDEKNVENEKKKKEKKDKKKKKPITRKELIERYSIVNIGGSVIPTFNPSFRIWEYNITDIVNDSNFAVSEYKPWDEFFESLNKIMEDSLLEDEMDSSNIEVGINREKMGEKKNKKKKKNDKTMPIEMPDKYELGPAYVPQLFTPTRFVQFYADLEKINQELHNSFVESKDIFRYEIEYTSDEKPYSMDSLTVGSYLDLAGRLYENKPAWEKYVEWSFASSGYKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * *::*:* *. * . * . . **. **** *: .:. :* : .*::**** * : .: :: : *. : * **:.* . :* :: *: :.. : * ::::** . . *: .* .*:: .*:* :: : : .: :. ... : * * :: .* . .: . : ..: : :* : . . : : . .* . ** :*. :: : : . : : : ", "identical_positions": 44, "similar_positions": 95, "identity": "6.24%" }, { "cls_id": "homologset.agr.MGI:1931441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QR99-1", "uniprot_id": "TGT_RAT", "id": "Q4QR99-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MAAVGSPGSLESAPRIMRLVAECSRSRARAGELRLPHGTVATPVFMPVGTQATMKGITAEQLDSLGCRICLGNTYHLGLRPGPELIQKAHGLHGFMNWPHNLLTDSGGFQMVSLISLSEVTEEGVRFRSPYDGEETLLSPERSVEIQNALGSDIIMQLDDVVSSTVTGPRVEEAMHRSVRWLDRCIAAHKRQDKQNLFAIIQGGLNADLRTTCLKEMTKRDVPGFAIGGLSGGESKEQFWKMVALSTSMLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVYPTRTARFGSALVPTGNLQLKKQQYAKDFSPINPECPCATCQTHSRAFLHTLLHSDNTAALHHLTVHNIAYQLQLLSAARSSILEQRFPDFVRNFMRTMYGDHSLCPAWAIEALASVGITLT--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMA2-1", "uniprot_id": "TGT_MOUSE", "id": "Q9JMA2-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MAAVGSPGSLESAPRIMRLVAECSRSGARAGELRLPHGTVATPVFMPVGTQATMKGITTEQLDSLGCRICLGNTYHLGLRPGPELIRKAQGLHGFMNWPHNLLTDSGGFQMVSLFSLSEVTEEGVHFRSPYDGEETLLSPERSVEIQNALGSDIIMQLDHVVSSTVTGPLVEEAMHRSVRWLDRCIAAHKHPDKQNLFAIIQGGLNADLRTTCLKEMTKRDVPGFAIGGLSGGESKAQFWKMVALSTSMLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVYPTRTARFGSALVPTGNLQLKKKQYAKDFSPINPECPCPTCQTHSRAFLHALLHSDNTTALHHLTVHNIAYQLQLLSAVRSSILEQRFPDFVRNFMRTMYGDHSLCPAWAVEALASVGIMLT--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXR0-1", "uniprot_id": "TGT_HUMAN", "id": "Q9BXR0-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MAGAATQASLESAPRIMRLVAECSRSRARAGELWLPHGTVATPVFMPVGTQATMKGITTEQLDALGCRICLGNTYHLGLRPGPELIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFRSPYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIRWLDRCIAAHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFWRMVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVPTGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAVRTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDALASVGITLG--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYK1-1", "uniprot_id": "TGT_DANRE", "id": "Q7SYK1-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MASVKAVSS--AAPLALRIVAECPVSKARACSLTLPHCAVNTPVFMPVGTQGTMKGITADQLEDLDCQICLGNTYHLGMRPGPDLIEKANGLHGFMKWRRNLLTDSGGFQMVSLVELSEVTEEGVTFRSPYDGKEILLTPEQSIAIQNSLGSDIMMQLDDVVSSTVKGPRVEEAMHRSVRWLDRCIAANKNPDRQNLFAIIQGGLDAELRKACLKEMTKRDVPGFAIGGLGGGEEKDDFWKMVTLSTDHLPREKPRYLMGVGYAVDLVVCVALGCDMFDCVFPTRTARFGSALVPWGSLQLKQKQYAKDFQPIDPDCQCPTCRRHSRAYLHALFKSD-TAAMHHITIHNISYQLSLMRSVRQSIIDQRFPEFVKEFMKRMFPSSSQYPSWAVEALQSVNICLS--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPY8-1", "uniprot_id": "TGT_DROME", "id": "Q9VPY8-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit", "aln": "------MGPSHIPPLTYKVVAECSVSKARAGLMTLRHSEVNTPVFMPVGTQGTLKGIVPDQLIELNCQILLGNTYHLGLRPGIETLKKAGGLHKFMGWPRAILTDSGGFQMVSLLQLAEIDEHGVNFRSPFDNSQCMLTPEHSIEIQNAIGGDIMMQLDDVVKTTTTGPRVEEAMERTIRWVDRCIEAHARDDDQSLFPIVQGGLDVPLRQRCVSALMERQVRGFAVGGLSGGESKHDFWRMVDVCTGYLPKDKPRYLMGVGFAADLVVCVALGIDMFDCVFPTRTARFGCALVDSGQLNLKQPKYKLDMEPIDKDCDCSTCRRYTRSYLHHIATNESVSSS-LLSIHNVAYQLRLMRSMREAIQRDEFPQFVADFMARHFKAEP-VPAWIREALSAVNIQLPADPERIDEQDQKPKTEKRRETEDVAEEQVASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .* ::****. * *** : * * * **********.*:***..:** *.*:* ********:*** : :.** *** ** * : :************..*:*: *.** ****:*..: :*:**:*: ***::*.**:****.**.:*..** ***** *::**:**** *: . * *.**.*:****:. ** *:. : :*:* ***:***.***.* :**:** :.*. **::*********:*.********* ******:********.*** *.*:*:: : *: **: :* *.**: ::*::** : .: .:: :::**::*** *: : * :* ..**:** :** : . *:* :** :*.* * ", "identical_positions": 205, "similar_positions": 109, "identity": "47.13%" }, { "cls_id": "homologset.agr.MGI:1931457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8H4-1", "uniprot_id": "CBLC_RAT", "id": "G3V8H4-1", "name": "E3 ubiquitin-protein ligase CBL-C", "aln": "-MAAATAP--QGWQ------------------------WGEPRALGRAVKLLQRLEEQCRDLRLFVG--PPSLRDLLPRTAQLLREVAKARSDKTRGDPEGPGGAGDFLVIYLTNLEAKGRQVAELLPHRGKKDANQDVFPEGSRFRRQLAKLALIFSHMHAELSALFPEGKYCGHLYQITKGSANTFWRENCGVRCVLPWAEFQSLLCSCHPVEPGPIMQALRSTLDLTCSGHVSVFEFDIFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQTRLQAYRDKPGSYIFRPSCTRLGQWAIGYVSSNGSILQTIPLNKPLLQVLLKGQKDGIFLYPDGKNHNPDLTELCRAVLNQCIQVSQEQLQLYQAMNSTFELCKICTERDKDVRIEPCGHLLCSCCLAAWQH-SDSQTCPFCRCEIKGREAVSIC---QAQERSMEVRTTAGDSGDNCHQE------------------------------------------------------AAEWKLESVTPS---------------------------------------------------------------------------------------------------------------------------APPLPPEVPCPQ----------------RPQNKGWLTL--------APFTLPRLRP-------------------PLPLPKMAS--VLWEVTS--------------RPQVREGATESS---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XL1-1", "uniprot_id": "CBLC_MOUSE", "id": "Q80XL1-1", "name": "E3 ubiquitin-protein ligase CBL-C", "aln": "-MAAAAAP--RGWQ------------------------RGEPRALSRAVKLLQRLEEQCRDPRMVTG--PPSLRDLLPRTAQLLGEVAKARR-EAREDPEGPGGADDFLAIYLANLEVKGRQVAELLPPRGKKDVNQDVFREGSRFRRQLAKLALIFSHMHAELSALFPAGKYCGHLYQLTKGSAHIFWRQNCGVRCVLPWAEFQSLLCACHPVEPGPTMQALRSTLDLTCNGHVSVFEFDVFTRLFQPWPTLLRNWQLLAVNHPGYMAFLTYDEVQTRLQAYRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPLNKPLLQVLLKGQKDGIFLFPDGKKHNPDLTELCRVEPYQRIQVSEEQLLLYQAMNSTFQLCKICAERDKDVRIEPCGHLLCSCCLAAWQD-SDSQTCPFCRCEIKGREAVSIC---QAQERPTEVRTAADGSRDNCHQE------------------------------------------------------AAEQKLGPVIPS---------------------------------------------------------------------------------------------------------------------------APSLLPEDQFPQ----------------GPQDKGWLTL--------APLALPRLRP-------------------PLPLPKMAS--VLWEVTS--------------RPRAREEATESS---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULV8-1", "uniprot_id": "CBLC_HUMAN", "id": "Q9ULV8-1", "name": "E3 ubiquitin-protein ligase CBL-C", "aln": "-MALAVAP--WGRQ------------------------WEEARALGRAVRMLQRLEEQCVDPRLSVS--PPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQH-SDSQTCPFCRCEIKGWEAVSIY---QFHG-----QATAEDSGNSSDQE------------------------------------------------------GRELELGQVPLS---------------------------------------------------------------------------------------------------------------------------APPLPP----------------------RPD-------------------LPPRKP-------------------RNAQPKVR----LLKGNS--------------PPAALGPQDPAPA--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PD63-1", "uniprot_id": "A0A8M9PD63_DANRE", "id": "A0A8M9PD63-1", "name": "E3 ubiquitin-protein ligase CBL", "aln": "MMAMARRPGTAGRSQ----------ISDTSETPSQPPTSADRKLLEKVLKRLDKLHKLSVDPRLALKNSPPYLPELLSETAIHLTEVWAPYRGSAMAVPR--WDEGDYMRIHIRHLLDKT-DRAVLLFKEGK----EKMFEETSNYRRNLTKLSLLFSHMLNELRTIFPGGRFQGDTYRVTKTEAKEFWRKTFGHKCIVQWNVFKQQLKRVHYFEEGMEAMALKSTVDLTCNDHISIFEFDIFTRLFQPWSTLIRNWNHLAVTHPGYMAFLTYDQVKARLEHYRHRPGSYIFRLSCTQMGQWAIGHVTSDGSIVQTIPQNTPLYQALIQGFREGCYLYPDGRDVNPDLSSLCSPVHKGRVKVTEEQYELYCEIGSTFQLCKICTERDKDTRIQPCGHLLCQPCLTGWQK-SDGHTCPYCRCDIRGTESILIEPYLPIRDKRAEEEEEDDEDDDDDEEEDHEDIELVMKKLACMKKI-----------------------------------SQEEYQIPRSSLS---------------------------------------------------------------------------------------------------------------------------PPPLPPKRNSSSPCP-----------SPKPQTHRSFSLGAQKVKNNSWSENMRRKPSSKRSEEHCE------DFQPSSLPCVRNSGVPWEGPSESVK-------RKKRDKRRDRKEEVSVRIVEDTTSLSGRHCHGEMEENTSS--------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSK2-1", "uniprot_id": "Q9VSK2_DROME", "id": "Q9VSK2-1", "name": "E3 ubiquitin-protein ligase CBL", "aln": "-MATRGSGTRVQSQPKIFPSLLSKLHGAISEACVSQRLSTDKKTLEKTWKLMDKVVKLCQQPKMNLKNSPPFILDILPDTYQRLRLIYSKNE-----DQMHLLHANEHFNVFINNLMRKCKQAIKLFK-EGK----EKMFDENSHYRRNLTKLSLVFSHMLSELKAIFPNGVFAGDQFRITKADAADFWKSNFGNSTLVPWKIFRQELNKVHPIISGLEAMALKTTIDLTCNDFISNFEFDVFTRLFQPWVTLLRNWQILAVTHPGYVAFLTYDEVKARLQRYILKAGSYVFRLSCTRLGQWAIGYVTAEGEILQTIPQNKSLCQALLDGHREGFYLYPDGQAYNPDLSSAVQSPTEDHITVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQIVVDAFDPRKQHNRNVTNGRQQQQEEDDTEDIGDFNIATSSLHALSTSSTVAAEKHSPHTSPRLGRRSTTPSLMAVQNDLYAGGTPTLSLPSSSCSSIAAASTSSSSSLASVATVAASTSSSQHQQPQPSAPPASAVLSNGGGGGGGGGASSSQKNTNRMSAPLIGSCVANSTYGQKLPQNCSHSSTSSSSDNASSSSSYAILQNLHDTGTPATAAAVVAPPLPPRKSSPGVETPSKATAPPPPSSSKSIDNIQCSLDNVPPQTTAPPIPPHVSPSVDTLAEDLMRQQLIATSTTSPVLSLLDEDIVEVGPAETISGVIDTRPLEARGVTLCRQDSASSHYTQLCTTSSGGSAAALANGKKANSAKQSQATTTTSAAAAAATAGNGSNPGQQSQPLLYANVTINQKDCGTVPYENINLEYIARLMNAGYSKENAITALGISRNNIEMAGDILREFVSKNSA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . : : * :. : :::: : . : :: ** : ::*. * * : .:.: :.: :* * : *: .*: :.:* *. **:*:**:::**** ** ::** * : *. :::** * **:.. * :: * *.. * * . * **::*:****...:* ****:******** **::**: ***.****:******:*: **: :.***:** ***::******:*:::*.*:**** *..* *.*:.* ::* :*:***: ****:. : *::** ** :.***:*****:* :** :*:******* **:.** *:.: **:**.:*:* * : : : . :. . * .: * .*.* * . * . : : . ", "identical_positions": 157, "similar_positions": 130, "identity": "17.66%" }, { "cls_id": "homologset.agr.MGI:1931464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZT1-1", "uniprot_id": "CALL5_HUMAN", "id": "Q9NZT1-1", "name": "Calmodulin-like protein 5", "aln": "MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTAAKKARAG--LEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JM83-1", "uniprot_id": "CALM4_MOUSE", "id": "Q9JM83-1", "name": "Calmodulin-4", "aln": "MSHGFTKEEVAEFQAAFNRFDKNKDGHISVEELGDVMKQLGKNLPEKDLKALISKLDTDGDGKISFEEFLTAIEKYKKGHRAGELRAVFNVLDQNGDGYITVDELKESLSKLGESLSQEELEDMIRVADVDQDGKVKYEEFVRLHVEN", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :* ** *::: **. .*.: :* *..:*** .:* ****.* :*: ***::*:****:***:***** :* : * :*:..*..:**:***:******:.::: **:.*.****: *** *******:*:****.*: .::", "identical_positions": 74, "similar_positions": 50, "identity": "50.0%" }, { "cls_id": "homologset.agr.MGI:1931465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8L1-1", "uniprot_id": "G3V8L1_RAT", "id": "G3V8L1-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "-MGRARDAILDALENLTADEFKKFKMKLLTAPVREGYGRIPRGALLQM-DPIDLTDKLVSYYLEGYGLELTMTVLRDMGIQELAEQLQKIMEE-------SGAVATATSVPAQGTARTE-HFVDQHRQALIARVTEVDGLLDALYG-NVLTEGQYQAVRAETTNQNKMRKLFS-FAPAWNLTCKNLFLEALRQTQPYLVTDLEQS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPB4-1", "uniprot_id": "ASC_MOUSE", "id": "Q9EPB4-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "-MGRARDAILDALENLSGDELKKFKMKLLTVQLREGYGRIPRGALLQM-DAIDLTDKLVSYYLESYGLELTMTVLRDMGLQELAEQLQTTKEE-------SGAVAAAASVPAQSTARTG-HFVDQHRQALIARVTEVDGVLDALHG-SVLTEGQYQAVRAETTSQDKMRKLFS-FVPSWNLTCKDSLLQALKEIHPYLVMDLEQS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULZ3-1", "uniprot_id": "ASC_HUMAN", "id": "Q9ULZ3-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "-MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSM-DALDLTDKLVSFYLETYGAELTANVLRDMGLQEMAGQLQAATHQG------SGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDALYG-KVLTDEQYQAVRAEPTNPSKMRKLFS-FTPAWNWTCKDLLLQALRESQSYLVEDLERS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9N6-1", "uniprot_id": "ASC_DANRE", "id": "Q9I9N6-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "MAESFKEHLQEAFEDLGADNLRKFKSKLGDRRQEP---RVTKSAIEKLKDEIDLADLMVGVFTSKDAVSVTVEILRAIKCNAVADDLLRNTGQSESKGALSDESKCASSKAVSKVAFSKVNFIDEHWKELIDRVNNVDPILDILRQKKVITNEDYCTIRNKETPQKKMRELLTGPITCAGNKGKEVLYDALRESNKFLMDDLEDAE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :*:*:* .::::*** ** . *:.:.*: .: * :**:* :*. : . . .:* :** : : :* :* : *. . . . . .* . :*:*:* ** **.:*: :** * .*:*: :* ::* : * .***:*:: .. . . *: : :**:: : :*: *** : ", "identical_positions": 49, "similar_positions": 72, "identity": "23.79%" }, { "cls_id": "homologset.agr.MGI:1931466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9Y2-1", "uniprot_id": "A0ABK0L9Y2_RAT", "id": "A0ABK0L9Y2-1", "name": "Selenoprotein K", "aln": "MVYIS-NGQVLDSRNQSPWR--LSFITDFFWGIAEFVVFFFKTLLQQD--VKKRRGYGGSSDSRYDDGRGPPGNP-PRRMG------RISHLRGPSPP------PMAGG--GR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLJ1-1", "uniprot_id": "SELK_MOUSE", "id": "Q9JLJ1-1", "name": "Selenoprotein K", "aln": "MVYIS-NGQVLDSRNQSPWR--VSFLTDFFWGIAEFVVFFFKTLLQQD--VKKRRGYGSSSDSRYDDGRGPPGNP-PRRMG------RISHLRGPSPP------PMAGGU-GR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6D0-1", "uniprot_id": "SELK_HUMAN", "id": "Q9Y6D0-1", "name": "Selenoprotein K", "aln": "MVYIS-NGQVLDSRSQSPWR--LSLITDFFWGIAEFVVLFFKTLLQQD--VKKRRSYGNSSDSRYDDGRGPPGNP-PRRMG------RINHLRGPSPP------PMAGGU-GR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I79-1", "uniprot_id": "SELK_DANRE", "id": "Q66I79-1", "name": "Selenoprotein K", "aln": "MVYVS-NGQVLDSRSRSPWS--LSFLTDFFWGAVEFIGLFFQTLVQPD--LSKDG--NNSASSRFSDGRGPPGFPGRRRMG------RINHGAGPTPP------PMGGGGUGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7Z2C4-1", "uniprot_id": "SELG_DROME", "id": "Q7Z2C4-1", "name": "Glycine-rich selenoprotein", "aln": "MVYIDHNGRVWEKRPWD-WRRIVELFVGIWFAIKQLFLTFLAPFTGNNNQANPRRGNGWGGGGGWGGGGGGGGGGGGGRPGSGSGGLRPNRRIGRIQPTMSCNMPAGGGU-G-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:. **:* :.* . * :.::..:::. ::. *: .: : . . .... :..* * * * * * .: * * * .** * ", "identical_positions": 21, "similar_positions": 35, "identity": "18.58%" }, { "cls_id": "homologset.agr.MGI:1931469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1L875-1", "uniprot_id": "Q1L875_DANRE", "id": "Q1L875-1", "name": "Sulfotransferase", "aln": "----------------------------MAQEECKMISDKLLKYKGTVLTMETNHDITPEYIDSLQDFETRDDDVFVVTFPKSGTVWTQ-------RIMTLIYEEDFPEKANEIT-YEQMPWIEYREKGKDYNARP--------SPRLFCSHLLEPLMPRALQ-KKGKVIYVMRNPKDVMVSYFHFSNKMKNLDSSENYDEILENFFTGCMIGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAINKVVERTTFNQMKVDPVAN---YESLPQEVTDQP--KGVFMRKGTVGDWKNSLTVAQSECVDRVFEERMKHVPLNLVWDIAELRG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L873-1", "uniprot_id": "Q1L873_DANRE", "id": "Q1L873-1", "name": "Sulfotransferase", "aln": "----------------------------MAQEECKMISDKLLKYKGTVLTLEPSYDITPEYIDSIQDFETRDDDVFVVTFPKSGTVWTQ-------RIITLIYEEDFPEKAKQIT-FEQMPWIEYREKGKDYSTRP--------SPRLFCSHLLEPLMPKTLK-RKGKVIYVMRNPKDVMVSYFHFSQKMKDLDSAKSYDEVLENFLTGCMVGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAIDKVVERATFKQMKVDPVAN---YESLPVDIIDQP--KGAFMRKGTVGDWRNSLTVAQSECVDRALEERMKDVPLNLVWDITELRG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P4Q2-1", "uniprot_id": "A0A8M9P4Q2_DANRE", "id": "A0A8M9P4Q2-1", "name": "Sulfotransferase", "aln": "----------------------------MAQEECKMLSDKLLNYKGTVLTVDIRHDITPEYIDSLQDFDARDDDVFVVAFPKSGNVFLQYMPHHMHRIMTLIX--DFPEKAKQIT-YKQMPWIEYQEKGKDYSTRPL------HSPRLFCSHLLEPLMPRALQ-KKGKVIYVMRNPKDVMVSYX-----------SRSYDEMLKKFITGCMIGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAIDKVVERATFNQMKVDPVAN---YESVPWKITDQP--KGVFLRKGTVGDWRNSLTVAQSECLDRAFEERMKEVP-NLVWDIAHFCG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35403-1", "uniprot_id": "ST3A1_MOUSE", "id": "O35403-1", "name": "Amine sulfotransferase", "aln": "----------------------------MDNKDEYLLNFKGYNFQKTLVKMEV--------VENIENYEIRDDDIFIVTYPKSGTIWTQ-------QILSLIYFEGHRNRTENIETIDRAPFFEYNIHKLDYAKMP--------SPRIFSSHIPYYLVPKGLKDKKAKILYMYRNPKDVLISYFHFSNLMLIFQNPDTVESFMQTFLDGDVVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDFRSSVLKICSFLEKELSEEDVDAVVRQATFQKMKADPRAN---YEHIIKDELGTRNEMGSFLRKGVVGAWKHYLTVDQSERFDKIFHRNMKNIPLKFIWDINEE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W1L8-1", "uniprot_id": "Q9W1L8_DROME", "id": "Q9W1L8-1", "name": "", "aln": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQ-----PVLDRVYDFEVRDDDVWIVTLPKCGTTWMQ-------ELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAIS-YFHHWR-GMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF40-1", "uniprot_id": "A0A0B4KF40_DROME", "id": "A0A0B4KF40-1", "name": "", "aln": "---------------MNRVQVTP-------RSYPTNLIDKDWGNRKLFYTKDSE-----NFLRLVHDMKLRDDDVWIVTLPKCGTTWMQ-------ELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSRYYHGVS-FGFNYGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHEN-AGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : . ****:::*: **.*. : * .: *: : : : *::*: . . ***:: **: ::* : : *::*: *** * :* . . :. .: . * : :.. :: ::* * :: : .:. *: : :.: :: : .: :* .*: :* * *:*:* *. :. *. . : . : . .: ", "identical_positions": 38, "similar_positions": 83, "identity": "6.76%" }, { "cls_id": "homologset.agr.MGI:1931520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923B1-1", "uniprot_id": "DBR1_MOUSE", "id": "Q923B1-1", "name": "Lariat debranching enzyme", "aln": "---MRVAVAGCCHGELDKIYETLALAERRGSGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYN----SSTIRSIYHVRNIEVYKLKQLKQPVHIFLSHDWPRNIYHYGNKKQLLKTKSFFRQEVENSTLGSPAASELLEHLQPAYWFSAHLHVKFAALMQH-------QATDKDQAGK-------------------------ETKFLALDKCLPHRDFLQVLEIEHDPSA-PEYLEYDVEWLTVLRATDDLINVTGGLWNMPEDNG--LHTRWDYSATEETMKEVMEKLNHDPKVPCNFTMTAACYDPS-----KPQTQVKLVHRINPQTTEFCAQLGITDINVMIQKAREEEHHQCG--EYEQQGDPGTEESEEDRSEYNTDTSALSS-INPDEIMLDEEEEEEEEEEEAVSAHSDMNTPSVEPAS---DQASDLSTS----FSDIRNLPSSMFVSSDDASRSPASGEGKC--GETVESGDEKDLAKFPLKRLSDEHEPEQRK----------KIKRRNQAIYAAVDDGDASAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK59-1", "uniprot_id": "DBR1_HUMAN", "id": "Q9UK59-1", "name": "Lariat debranching enzyme", "aln": "---MRVAVAGCCHGELDKIYETLALAERRGPGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTLFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYN----SSTIRSIYHVRNIEVYKLKQLKQPIDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQH-------QAKDKGQTAR-------------------------ATKFLALDKCLPHRDFLQILEIEHDPSA-PDYLEYDIEWLTILRATDDLINVTGRLWNMPENNG--LHARWDYSATEEGMKEVLEKLNHDLKVPCNFSVTAACYDPS-----KPQTQMQLIHRINPQTTEFCAQLGIIDINVRLQKSKEE-HHVCG--EYEEQDDVESNDSGEDQSEYNTDTSALSS-INPDEIMLDEEED----EDSIVSAHSGMNTPSVEPS----DQASEFSAS----FSDVRILPGSMIVSSDDTVDSTIDREGKP--GGTVESGNGEDLTKVPLKRLSDEHEPEQRK----------KIKRRNQAIYAAVDDDDDDAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3E4-1", "uniprot_id": "DBR1_DANRE", "id": "Q7T3E4-1", "name": "Lariat debranching enzyme", "aln": "---MKVAVEGCCHGELDKIYESISYLENKDGVKVDLLLCCGDFQAVRNEGDMKCMAVPAKYRHMQTFYKYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGYAGVIRYKGVRIGGLSGIFKSHDFKKGHFEFPPYN----PETLRSVYHIRNIDVFKLKQIKMPIDIFMTHDWPRGIYHYGNTNALLRQKKFLRQEVESSTLGSPAAADLLEHLQPSYWFSAHLHVKFAALMQH-------EAKN-NTAPK-------------------------ITKFLSLDKCLPHRDFLQIVEVADRPGS-SEQLEYDPEWLAILKATDNLQKPTCNFWNPPQDNG--LHSRWDFSASEEAMMEVVSDLSGDLCIPENFSLTVPPYDPS-----QPQPHALPAYSTNPQTTELCATLNLTDIYILAGQSGQIYGERGGKGATEEEDEEDSTGSADEPSDFPSDTSGLSSSYNPDEITIEDEWEEE--EDGGVGCGEGKGMDAVVPEGQVGSQDSDRDSSPQRETAKRLILPAPCAKPKTEAPLHSLPRLSLPPPSACVSQGSSEEEGAFTAARVPKRTSGETTQSSAGQTGGTPQIKRRNQSIYTAVEDEESDS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSD7-1", "uniprot_id": "DBR1_DROME", "id": "Q9VSD7-1", "name": "Lariat debranching enzyme", "aln": "---MKIAVEGCAHGELERIYDTIEGIEKVGGTKIDLLLCCGDFQSTRNLEDLQTMAVPKKYLDMCSFYKYYSGELVAPVLTIFIGGNHEASNYLQELPYGGWVAPNIYYLGYAGVVNVNGVRIAGISGIFKGHDFLRGHHEFPPYT----DSTCRSVYHVRQLEVFRLKQISGRVDIFLSHDWPTGIYEYGNKAQLLRKKPFFAADMESGKLGSQPLEELLKAVQPAYWFAAHLHCKFAALVPHNHSQKLGDAESSSSSSSSEDEDEEREKVKKAAPVPPPSKSVPVTKFLALDKCLPRRAFLQVVEVPSDPIEGTPRLEYDAEWLAILHSTNHLISVKENYYYLPGKKAGEFTERSNFTPTEEELEAVTAKF-QKLQVPENFERTVPAFDPAEQSDYKHMFVDQPKVQLNPQSNTFCATLGIDDPLCLVLLANGLDLPAVG---------------ATECKDRETKSSKLQA------------------------VEEDVAEPLVTPT------KRKLNLS----------LPAPTTAAADTTDENVIDLPEEE-----AEEAIIATETPHVEEPASVPASPNVKK-----------LKRRNQNIYQAQED------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24309-1", "uniprot_id": "DBR1_YEAST", "id": "P24309-1", "name": "Lariat debranching enzyme", "aln": "MTKLRIAVQGCCHGQLNQIYKEVSRIHAK--TPIDLLIILGDFQSIRDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKH-------NKRSHEPPNK-------------------------STSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEP---------DTSHASWKDENHRMFWDPEFINNLVICQKNKNLLS----NKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQ---------------------KDEVRQTKAFISKFMT--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::** **.**:*::**. : . :***: ****: *: *:: :*:* ** : * **..* *** *:*******: .:* **:**:** **:*:* :.*: .*:**..:***:* *: : : : . *.:**:* :: * :. :.*:::**** .: :*:. **: * *: :::...*** :**. ::* :*::**** :* * : * : . . *. :: : . : *** :: : . : .:. : . . *: : : . .. :. : : : : * : : ", "identical_positions": 92, "similar_positions": 111, "identity": "14.86%" }, { "cls_id": "homologset.agr.MGI:1931523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4ABE3-1", "uniprot_id": "Q4ABE3_DROME", "id": "Q4ABE3-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKEHGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKK-VASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEK--AKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABD8-1", "uniprot_id": "Q4ABD8_DROME", "id": "Q4ABD8-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLEERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKK-VASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEK--AKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02255-1", "uniprot_id": "H1_DROME", "id": "P02255-1", "name": "Histone H1", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKK-VASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEK--AKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB54-1", "uniprot_id": "Q4AB54_DROME", "id": "Q4AB54-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKK-VASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEK--AKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB94-1", "uniprot_id": "Q4AB94_DROME", "id": "Q4AB94-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVGQKKASGSAGTKAKKASATPSHPPTQQMGDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKK-VASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEK--AKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43275-1", "uniprot_id": "H11_MOUSE", "id": "P43275-1", "name": "Histone H1.1", "aln": "------MSETAPVAQAASTATEKPAAAKKTKKPAKAAAP-RKKPAGPSVSELIVQAVSSSKERSGVSLAALKKSLAAAG-YDVEKN--NSRIKLGLKSLVNKGTLVQTKGTGAAGSFKLNKKA---ESKAITTKVSVKAKASGAAK-KPKKTAGAAAKKTVKTPK----KPKKPAVSKKTS--KSPKK--PKVVKAKK-------VAKSPAKAKAVKPKASKAKVT--KPKTPAKPKKAAPKKK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3K5-1", "uniprot_id": "H11_RAT", "id": "D4A3K5-1", "name": "Histone H1.1", "aln": "------MSETAPVPQPASVAPEKPAATKKTRKPAKAAVP-RKKPAGPSVSELIVQAVSSSKERSGVSLAALKKSLAAAG-YDVEKN--NSRIKLGLKSLVNKGTLVQTKGTGAAGSFKLNKKA---ESKASTTKVTVKAKASGAAK-KPKKTAGAAAKKTVKTPK----KPKKPAVSKKTSS-KSPKK--PKVVKAKK-------VAKSPAKAKAVKPKAAKVKVT--KPKTPAKPKKAAPKKK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02539-1", "uniprot_id": "H11_HUMAN", "id": "Q02539-1", "name": "Histone H1.1", "aln": "------MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAG-YDVEKN--NSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASK-KLKKATG-ASKKSVKTPK----KAKKPAATRKSS--KNPKK--PKTVKPKK-------VAKSPAKAKAVKPKAAKARVT--KPKT-AKPKKAAPKKK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53551-1", "uniprot_id": "H1_YEAST", "id": "P53551-1", "name": "Histone H1", "aln": "--MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASSKSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQPKGPAGAVKLAKKKSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . .* . : . . : .: . :: . . :*: * * *:** : . :: :*. * * : *.** ..: .: . .. : .* . : . : *.. ..**. . . : : * .: . * . : . *..: .: : . ", "identical_positions": 20, "similar_positions": 65, "identity": "7.66%" }, { "cls_id": "homologset.agr.MGI:1931526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4ABE3-1", "uniprot_id": "Q4ABE3_DROME", "id": "Q4ABE3-1", "name": "", "aln": "MSDSAVATSASPVAAPPATV--EKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKEHGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSK-KVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVS-------AKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABD8-1", "uniprot_id": "Q4ABD8_DROME", "id": "Q4ABD8-1", "name": "", "aln": "MSDSAVATSASPVAAPPATV--EKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLEERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSK-KVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVS-------AKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02255-1", "uniprot_id": "H1_DROME", "id": "P02255-1", "name": "Histone H1", "aln": "MSDSAVATSASPVAAPPATV--EKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSK-KVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVS-------AKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB54-1", "uniprot_id": "Q4AB54_DROME", "id": "Q4AB54-1", "name": "", "aln": "MSDSAVATSASPVAAPPATV--EKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSK-KVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVS-------AKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB94-1", "uniprot_id": "Q4AB94_DROME", "id": "Q4AB94-1", "name": "", "aln": "MSDSAVATSASPVAAPPATV--EKKVGQKKASGSAGTKAKKASATPSHPPTQQMGDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSK-KVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVS-------AKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15864-1", "uniprot_id": "H12_MOUSE", "id": "P15864-1", "name": "Histone H1.2", "aln": "MSEAAP---AAPAAAPPA----EKAPAKKKAAKKPAGVRRKASG----PPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKN--NSRIKLGLKSLVSKGILVQTKGTGASGSFKLN------------KKAASGEAKPQAK-KAGAAKA-----KKPAGAA-KKPKKATGAATPKKAAKKTPKKAKKPAAAA---VTKKVAKSPKKAKVTKPKK-VKSASKAVKPKA-------AKPK--VAKAKKVAAKKK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K654-1", "uniprot_id": "A0A0G2K654_RAT", "id": "A0A0G2K654-1", "name": "", "aln": "MSETAP---AAPAAAPPA----EKAPAKKKAAKKPAGMRRKASG----PPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKN--NSRIKLGLKSLVSKGILVQTKGTGASGSFKLN------------KKAASGEAKPKAK-KAAAAKA-----KKPAGAA-KKPKKATGAATPKKAAKKTPKKAKKPAAAA---VTKKVAKSPKKAKVTKAKK-VKSASKAVKPKA-------AKPK--VAKAKKVAAKKK---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16403-1", "uniprot_id": "H12_HUMAN", "id": "P16403-1", "name": "Histone H1.2", "aln": "MSETAP---AAPAAAPPA----EKAPVKKKAAKKAGGTPRKASG----PPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKN--NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN------------KKAASGEAKPKVK-KAGGTKP-----KKPVGAA-KKPKKAAGGATPKKSAKKTPKKAKKPAAAT---VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKA-------AKPK--VVKPKKAAPKKK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53551-1", "uniprot_id": "H1_YEAST", "id": "P53551-1", "name": "Histone H1", "aln": "MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASS----KSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQPK--GPAGAVKLAKK---------KSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::. . ** :: .* * .. .:**. . :: .: :*: * * *:** : . :: :*. * * : *.* *.:*:.** . . * : . * * .. . * ..:: ** : . : :* .. :. : . . * . :. . : : * * : . . ", "identical_positions": 32, "similar_positions": 64, "identity": "11.72%" }, { "cls_id": "homologset.agr.MGI:1931527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4ABE3-1", "uniprot_id": "Q4ABE3_DROME", "id": "Q4ABE3-1", "name": "", "aln": "---MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKEHGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKK-EKDPKAKSK-VLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABD8-1", "uniprot_id": "Q4ABD8_DROME", "id": "Q4ABD8-1", "name": "", "aln": "---MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLEERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKK-EKDPKAKSK-VLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02255-1", "uniprot_id": "H1_DROME", "id": "P02255-1", "name": "Histone H1", "aln": "---MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKK-EKDPKAKSK-VLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB54-1", "uniprot_id": "Q4AB54_DROME", "id": "Q4AB54-1", "name": "", "aln": "---MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKK-EKDPKAKSK-VLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB94-1", "uniprot_id": "Q4AB94_DROME", "id": "Q4AB94-1", "name": "", "aln": "---MSDSAVATSASPVAAPPATVEKKVGQKKASGSAGTKAKKASATPSHPPTQQMGDASIKNLKERGGSSLLAIKKYITATYKCDAQKL--APFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKK-EKDPKAKSK-VLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43274-1", "uniprot_id": "H14_MOUSE", "id": "P43274-1", "name": "Histone H1.4", "aln": "---MSETAPAAPAAPAPA-----EKTPVKKKARKAAGGAKRKTSG----PPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKN--NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKRAGAAKAKKPAGAAKKPKKAAGTATAKKSTKKTPKKAKKPAAAAGAKKAKSPK--KAKATKAKK-------APKSPAKAKTVKPKAAKPKTSKPK---AAKPK-----------------KTAAKKK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15865-1", "uniprot_id": "H14_RAT", "id": "P15865-1", "name": "Histone H1.4", "aln": "---MSETAPAAPAAPAPA-----EKTPIKKKARKAAGGAKRKASG----PPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKN--NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGTATPKKSTKKTPKKAKKPAAAAGAKKAKSPK--KAKATKAKK-------APKSPAKARAVKPKAAKPKTSKPK---AAKPK-----------------KTAAKKK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10412-1", "uniprot_id": "H14_HUMAN", "id": "P10412-1", "name": "Histone H1.4", "aln": "---MSETAPAAPAAPAPA-----EKTPVKKKARKSAGAAKRKASG----PPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKN--NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPK--KAKAAKPKK-------APKSPAKAKAVKPKAAKPKTAKPK---AAKPK-----------------KAAAKKK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53551-1", "uniprot_id": "H1_YEAST", "id": "P53551-1", "name": "Histone H1", "aln": "MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASSK-----SYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQPKG--PAGAVKLAKKKSP---EVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: ::. . .* **. : ::. . :* . :: .: :*: * * *:** : . :: :*. * * : *.** .:*:.** . . * : ..:: . : . . . .:: * : . ** . :. ..... . : . : . * . .: .::: . : * ** ", "identical_positions": 27, "similar_positions": 75, "identity": "10.07%" }, { "cls_id": "homologset.agr.MGI:1931551", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER71-1", "uniprot_id": "RHOJ_MOUSE", "id": "Q9ER71-1", "name": "Rho-related GTP-binding protein RhoJ", "aln": "------------MSCRERTDSSCGCNGHEENRILKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKGCLGCHGCCAII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4E5-1", "uniprot_id": "RHOJ_HUMAN", "id": "Q9H4E5-1", "name": "Rho-related GTP-binding protein RhoJ", "aln": "------------MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKRCSEGHSCCSII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZD5-1", "uniprot_id": "Q5TZD5_DANRE", "id": "Q5TZD5-1", "name": "", "aln": "MPTLSSKSRQNALEAAEDGGSNSDPVNTTAKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYIPTVFDHYAVNVTVSGRQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELRSCMPHVPYILIGTQIDLRDDPKTLARLLQMKEKPLTYEQGLKLAREIGAQCYLECSALTQKGLKTVFDEAILTIFSPKKQKRGCAACRCCCALV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19073-1", "uniprot_id": "CDC42_YEAST", "id": "P19073-1", "name": "Cell division control protein 42", "aln": "------------------------------MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIKK-----SKKCAIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *****************:**:.: ** :*:*****:***.* :... : ***:********::*******.*****:****:.*.*:.**:*:*.**:: * ** :::********* : :* : :*:* *:* :**: : * *:*******:*** ******:: : * *: *:::", "identical_positions": 106, "similar_positions": 50, "identity": "46.9%" }, { "cls_id": "homologset.agr.MGI:1931553", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJL4-1", "uniprot_id": "RHOQ_RAT", "id": "Q9JJL4-1", "name": "Rho-related GTP-binding protein RhoQ", "aln": "MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPVCVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R527-1", "uniprot_id": "RHOQ_MOUSE", "id": "Q8R527-1", "name": "Rho-related GTP-binding protein RhoQ", "aln": "MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPVCVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17081-1", "uniprot_id": "RHOQ_HUMAN", "id": "P17081-1", "name": "Rho-related GTP-binding protein RhoQ", "aln": "MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************************************************************************************************************************************:**************************************************************", "identical_positions": 204, "similar_positions": 1, "identity": "99.51%" }, { "cls_id": "homologset.agr.MGI:1931556", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX06-1", "uniprot_id": "D3ZX06_RAT", "id": "D3ZX06-1", "name": "", "aln": "MPVLWLLFLLP-LLPLLAMLCQQRSPGARPCWLISLQHRVACVVLSWAAAWQRRKLEQSTLNVSQSQQQALMGCLKEAQGSCCLPRENTDMTTFRN-LPLTKTSHTQQKESEEKLLPPTLPQYHGDASLQATLLGLMTLNKAYPEVLAPGSTACVTPTSPWPYSVPWLGHALGRVSPIGAKDARTLLLEALISPGLRVLEARTAVELLDVFVGLEADGEELAEVIASGSLG-KLPRRAAELQEALEQGPRGLALRLWPKLQVVVTLDAGGQAEAVAALRVLWCQGLAFFSPAYAASGGVMALNLWPEQPQGSYLLSPGVPFIELLPIKEGTQEEAASTLLLTDVRREEKYELVLTDSTSLTRCRLGDVVQVIGTYNQCPVVRFTCRLGQTLSVRGEVTDENVFSVALAQAVGQWPGAKLLDHVCVESHILDSYEGSAPHYEVFVELRGLRNLSEENRDKLDHCLQEASPRYKSLRFWGSVGPAKVHLVRPGSFRVLREALAACPSSSC--PEMPRVLRLRHLAQLLQKRVIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J23-1", "uniprot_id": "GHDC_MOUSE", "id": "Q99J23-1", "name": "GH3 domain-containing protein", "aln": "MLLLWLLLLLLLLVPLLAILWQQRSRGARPCWLISLQHRVAWGMLGWAAAWQQWRLDRSTLNVGQSQQQALMWCLKKAQGSCCLPREDTDMRTFRNHLPLTQTSHTQEQESEETLPSPASPQYHGDASLQATLLGLITLNKAYPEALAPGSTACVTPTSPWPCSVPWLGHALGRVSPDGAKDPRTLLLEALISPGLRVLEARTAVELLDVFVGLEADGEELAEAIAAGILGTLLPKRAAELKEALEQGPRGLARRLWPKLQVVVTLDSGGQAEAVAALRVLWCQGLAFFSPAYAASGGVVALNLWPERPQGSYLLPPGVPFIELLPIKEGTQEEAASTLLLTDAQREKEYELVLTNHTSLTRCRLGDVVQVVGTYNQCPVVRFTCRLGQTLNVRGEVTDETVFSVALAQAVGQWPGAKLLDHVCVESRVLDSCEGSAPHYEVFVELRGLRNLSEENRDKLDNCLQEASAQYKSLRFRGSVGPAKVHLVRPGSFRVLREALAAFSSSSCRPPEMPRVIRLRHLAQLLQKRVIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N2G8-1", "uniprot_id": "GHDC_HUMAN", "id": "Q8N2G8-1", "name": "GH3 domain-containing protein", "aln": "-MLLWPLLLLLLLLPTLALLRQQRSQDARLSWLAGLQHRVAWGALVWAATWQRRRLEQSTLHVHQSQQQALRWCLQGAQRPHCSLRRSTDISTFRNHLPLTKASQTQQEDSGEQPLPPTSNQDLGEASLQATLLGLAALNKAYPEVLAQGRTARVTLTSPWPRPLPWPGNTLGQVGTPGTKDPRALLLDALRSPGLRALEAGTAVELLDVFLGLETDGEELAGAIAAGNPGAPLRERAAELREALEQGPRGLALRLWPKLQVVVTLDAGGQAEAVAALGALWCQGLAFFSPAYAASGGVLGLNLQPEQPHGLYLLPPGAPFIELLPVKEGTQEEAASTLLLAEAQQGKEYELVLTDRASLTRCRLGDVVRVVGAYNQCPVVRFICRLDQTLSVRGEDIGEDLFSEALGRAVGQWAGAKLLDHGCVESSILDSSAGSAPHYEVFVALRGLRNLSEENRDKLDHCLQEASPRYKSLRFWGSVGPARVHLVGQGAFRALRAALAACPSSPFP-PAMPRVLRHRHLAQCLQERVVS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** *:** *:* **:* **** .** .** .****** * ***:**: :*::***:* ******* **: ** . * *..**: **** ****::*:**:::* * .*: * *:********** :*******.** * ** ** ***** .:** *::**:*.. *:**.*:***:** *****.*** *********:***:****** .**:* * * .*****:*********** *************:********** .*******************:.*** **:*:* ***.**.*******:**************::.:: ::******: :***********:*:*:********* ***.***.**** .* :** **.:*****.******* **** :*** ********** ****************:******.:****** ******:**** *:**.** **** .**. * ****:* ***** **:**:.", "identical_positions": 368, "similar_positions": 88, "identity": "69.17%" }, { "cls_id": "homologset.agr.MGI:1931560", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99J87-1", "uniprot_id": "DHX58_MOUSE", "id": "Q99J87-1", "name": "ATP-dependent RNA helicase DHX58", "aln": "------------------------------------------------------------------------------------MELRPYQWEVILPALEGKNIIIWLPTGAGKTRAAAFVAKRHLETVDRGKVVVLVNRVHLVSQHAEEFRRMLDKHWTVTTLSGDMGSRAGFGLMARSHDLLICTAELLQLALNSSEEDEHVELREFSLIVVDECHHTHKDTVYN------TILSRYLEQKLKKAEPLPQVLGLTASPGTGGATKLQGAIDHILQLCANLDTCH--------------IMSPKNCYSQLLMHNPKPCKQYDLCQRRAQDPFGDLIKK-------------------LMNQIHQQLEMPDLKQQFGTQMYEQQVVQLCKDAAEAGLQEQRVYALHLRRYNDALFIHDTVRARDALDMLQDFYD------RERTTKTQMVRAESWLLKLFDDHKNVLGQLAARGPENPKLEMLERILLKQFGSPGHTRGIIFTR-------------TRQTASSLLLWLRQQPCLQTVGIKPQMLIGAGNTSQSTHMTQKDQQEVIQEFRDGILSLLVATSVAEEGLDIAQCNVVVRYGLLTNEISMVQARG---RARAGQSVYSFLATEGSREMKRELTNEALEVLMEKAVAAVQKMD--------------------PDEFKAKIRDLQQAS----------------LVKRAARAAHREIQQGQFLPEHVQLLCINCMVAVG----------------------------------------------------------------------------YGSDLRKVEGTHHVNVNPNFSVYYTTSQNPVVINKVFKDWR----------------------------------PGGT--------------IRCSNCGEVWGFQMIYKSVTLPVLK----------IGSILLETPRGKIQAKKWSRVPFSIPVFDILQDCTQSLSELSLD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD46-1", "uniprot_id": "D3ZD46_RAT", "id": "D3ZD46-1", "name": "RNA helicase", "aln": "------------------------------------------------------------------------------------MELRPYQWEVILPALEGKNIIIWLPTGAGKTRAAAFVAKRHLETVDRGKVVVLVNRVHLVNQHAEEFRRMLDKQWTVTTLSGDMGSRAGFGLLARSHDLLICTAELLHLALKSSEEDEHVELTEFSLIVVDECHHTHKDTIYN------TILSRYLEHKLKKAKPLPQVLGLTASPGTGGATKLQGAIDHILQLCANLDTWR--------------IMSPKNCYSQLLEHNPKPCKQYDLCQRRTQDPFGDLLKK-------------------LMKQIHQQLEMPDLKQQFGTQMYEQQVVQLSKDAAEAGLQEQRVYALHLRRYNDALYIHDTVRAWDALNMLQDFYD------TERALKTQMVHAERWLLELFDDHRKALAQFAAQGPENPKLEMLEGILLKQFGSPDHTRGIIFTR-------------TRQTASSLLLWLRQQPCLQTVNIKPQMLIGAGNTGQSTHMTQKDQQEVIQEFRDGKLNLLVATSVAEEGLDIAQCNVVVRYGLLTNEISMVQARG---RARAGQSVYSFVATEGSREIKRELTNEALEVLMEQAVAAVQKMD--------------------PEEFKAKIQDLQLAS----------------LVKRAARAAHRESQQGQFPPDRVQLLCINCMVAVG----------------------------------------------------------------------------YGSDLRKVEGTHHVNVNPDFSVYYTTSQNPVVINKVFKDWK----------------------------------PGGI--------------IRCSNCGEVWGFQMIYKSVTLPVLK----------IRSMLLETPHGKIQAKKWSRVPFSVPDFDILRDCTQSLSDLSLD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96C10-1", "uniprot_id": "DHX58_HUMAN", "id": "Q96C10-1", "name": "ATP-dependent RNA helicase DHX58", "aln": "------------------------------------------------------------------------------------MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHVELTVFSLIVVDECHHTHKDTVYN------VIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDGAINHVLQLCANLDTWC--------------IMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKK-------------------LMDQIHDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHLRRYNDALLIHDTVRAVDALAALQDFYH------REHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEMLEKILQRQFSSSNSPRGIIFTR-------------TRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARG---RARADQSVYAFVATEGSRELKRELINEALETLMEQAVAAVQKMD--------------------QAEYQAKIRDLQQAA----------------LTKRAAQAAQRENQRQQFPVEHVQLLCINCMVAVG----------------------------------------------------------------------------HGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKVFKDWK----------------------------------PGGV--------------ISCRNCGEVWGLQMIYKSVKLPVLK----------VRSMLLETPQGRIQAKKWSRVPFSVPDFDFLQHCAENLSDLSLD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40562-1", "uniprot_id": "MPH1_YEAST", "id": "P40562-1", "name": "ATP-dependent DNA helicase MPH1", "aln": "MASADDYFSDFEDDELDKLYEKAINKSVKETITRRAVPVQKDLHDNVLPGQKTVYEEIQRDVSFGPTHHELDYDALSFYVYPTNYEVRDYQYTIVHKSLFQN-TLCAIPTGMGKTFIASTVMLNYFRWTKKAKIIFTAPTRPLVAQQIKACLGITGIPSDQTAILLDK-SRKNREEIWANKRVFFATPQVVENDLKRG----VLDPKDIVCLVIDEAHRATGSSAYTNVVKFIDRFNSSYRLLALTATPASDLEGVQEVVNNLDISKIEIRTEESMDIVKYMKKRKKEKIEVPLLLEIEDIIEQLGMAVKPVLQQAIELGIYEECDPSQINAFKAMQQSQKIIANPTIPEGIKWRNFFILQLLNNVGQMLKRLKIYGIRTFFNYFQNKCTEFTTKYNLKKSTNKIAAEFYYHPILKNIKNQCENYLSDPKFVGHGKLQCVRDELMDFFQKRGSDSRVIIFTELRESALEIVKFIDSVADDQIRPHIFIGQARAKEGFDEVKYTRKHAPKGRKKVERLHRQEQEKFLEAERTKRAANDKLERSARRTGSSEEAQISGMNQKMQKEVIHNFKKGEYNVLVCTSIGEEGLDIGEVDLIICYDTTSSPIKNIQRMGRTGRKRDGKIVLLFSSNESYKFERAMEDYSTLQALISKQCIDYKKSDRIIPEDIIPECHETLITINDENEIINEMEDVDEVIRYATQCMMGKKVKPKKAITKKKRVQENKKPKKFFMPDNVETSIVSASTLINKFLVNESGGKQLVTSNENPSKKRKIFKALDNLENDSTEEASSSLETEDEEVSDDNNVFIAEGQNGCQKDLETAIIRTGESLTTLKPLHNFER-PNMALFVNDCGLPTKIEKNVKDIRGNQHNLEKEKSCTVDKNNMVLSLDDWNFFRNRYIPEGVSFDVEPNFVQYTKGVKVPHCHKVSKIITLFNDESNDNKKRTIDMNYTKCLARGMLRDEKKFVKVNDKSQVDNNSVNHDSSQSFTLSNAELDDILGSDSDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* **: :: :* : : :*** *** *: * .::. .. .*::. . ** *: : : . *:: * .* . : : :::.*.:::. *. :: : :*:**.*:: .: *. :. . * * .:: *: .. . :*:: :. ::: :.. *:. . : :. *: *. :.* : :. ::. ::: :* . : :* : : : . : . : :: . : . * ..: : . :. : * : . . :. . .. : :* : :: .:. . .. :: *: * : : :** ** .:* : : : :. *:.: .* : *.*: *:***::*:.* .:**.**:.****** . :::: *. :. *. :* * * * .: * * :.*. : : .:*:.*:.: :* * * ::.*:: . .: :. ..: : * :.*: :.. . :. *..* .:: *:.: *::: : . . *. *:* .** : * * : :* :* : :::. . * : :*. : ::.:. *:* . .* : : . ::*. ", "identical_positions": 103, "similar_positions": 257, "identity": "10.3%" }, { "cls_id": "homologset.agr.MGI:1931595", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6U7-1", "uniprot_id": "A0A0G2K6U7_RAT", "id": "A0A0G2K6U7-1", "name": "NF-kappa-B inhibitor zeta", "aln": "MIVDKLLDDSRGGEGLLDAAGDCGLMTSPLNLAYFYGASPPS-APGAGDTGYLSAVPSAPGSPGSDSSDFSSTSSVSSCGAVESRPRGGARAERPQVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSNKQKTSGQAVDEFKTQSVNIEQLTDLKSAVSAVGKRKGPDPLADGPVCKRPALLPTHFVTSPQTSPRGESMEDARHSESKLESSAALLQNIINIKNECNPVSLNTVQVSWMSP-VVPQNSPRDQRQDFHGGQSFSPPQKYQPFQVGGSPQMMEQASMFQYSPQGQNMQQPQPLPPQQQQQQQQQQQQQQQQQQQQQQNYPHNPPLQFSPYSRISQSPKYDSNLFDNQDSQFCTSQSFVSLLTGQGESETMAVPVQASHSVPPQNETQLQNFSLMPSSACEAVG-AHDAGSHSLGGSLSLQNIMGGPMNTTQLGKSFFQWQVEQEESKLANISQEQFLSRDGDGDTFLHIAVAQGRRALSYVLARKMNALHMLDVKEHNGQSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVLAHNSVVHDLQRSQQPHSPEVQDLLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRVPPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EST8-1", "uniprot_id": "IKBZ_MOUSE", "id": "Q9EST8-1", "name": "NF-kappa-B inhibitor zeta", "aln": "MIVDKLLDDSRGGEGLLDAAGDCGLMTSPLNLAYFYGASPPS-APGAGDTGYLSAVPSAPGSPGSDSSDFSSTSSVSSCGAVESRPRGGARAERPQVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSNKQKASGQPVDEFKTQSVNIEQLTDLKSAVSAVGKRKGPDPLSDGPVCKRPALLPSHFVTSPQTPTPGESMEDVRHSESKLDSSAALLQNIINIKNECNPVSLNTVQVSWMSP-TVPQNSPRDQCQDFHGGQAFSPPQKYQPFQVSGSPQMMDQASMYQYSPQTQNMQQPPPLPPQQQ----------------HQQNYPHNSPLQFSPYSRMSQSPKYDSNLFDTHEPQFCTGQSFVSLLTGPGEPESLAVPVPAPTSIPPQTETQLQTFSLMPSNACEAVVGVHDVGSHSLGTSLSLQNIMGSPMNTTQLGKSFFQWQVEQEESKLANIPQDQFLARDGDGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVVAHNAVVHELQRNRQSHSPEVQDLLLRNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYH8-1", "uniprot_id": "IKBZ_HUMAN", "id": "Q9BYH8-1", "name": "NF-kappa-B inhibitor zeta", "aln": "MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAPGSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQ--------------------------QPHYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAHLHSFSMMPSSACEAMV-GHEMASDSSNTSLPFSN-MGNPMNTTQLGKSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q7W9-1", "uniprot_id": "A0A8M9Q7W9_DANRE", "id": "A0A8M9Q7W9-1", "name": "", "aln": "-MTSRTFKTPSG-----APVRHSEQQQQQQQKMIIDRVSDGFSGLLDRDADLISPVQ-LWGFPGCSSP----TEPLLSPGEPSSDS------EHSWSDASVEAEGTRRSRYQGVRVKNTVKELIMRRKHLHTQVQQQ---------------------------------------------------------------------QFAVDDECAVLQ---SRKRTAESVCFSAVKRARATDGYTPMECVSSDCDLLEDLGVFLAP----PLSVGS-----VMESVCADAP------------------------------------------------------PLYMQNTLPAVQN---------TLPAVQNTLPAVQNTLPAAPPV------------------------------------------------------SFFQWQIQQEDEKLSALSPAELMSRDEDGDTFLHIAVAQGRRALAFVLASRMAELGVLDLKEHNQQSALQVCVAADQHLIAQDLLSLGADPNTFDRWGRSPLHVCAEKGHSATLQAIQRCVQQSGRSLSLEMVNYEGLTPLHTAVLAHNAVLQELSG----HVTQDVTLLQKRKKLAECIATLLQMGAALGTQDCKSGRTALHMAAEQVNVELLRLFLDQPDCCSVINTRAFSGNTALHMASALQGRDAQLEAVRLLLRRGADPSARNLENEQPAQLVNEGPLGDQVRRVLKGKSAPLRP---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: :. . * .. . . : : .* . *:. * **..*. :..: * * .* . *: :. : . :*. :*******:****::: : : :.. * : :... :** . *. ...*.:.:*: : . .* .. .: : :.. * .* *:.* . *: :* * * * : : :* : .: :. .: *:****::**:.**: :. :::::* *****************::*** :* * :**:**** ***:**.***:****.***:.:**: ** * ***:*********** .*****: . *.: :.** .**:****** **:***:*:::*. * .: ** :.*.*.: * *:*****: ::* ********:***:.*:**:****: *.* *.:*::*:.******:*::** * :**:*****:*:*****:********.:** :**:*:*:**:***** * ", "identical_positions": 216, "similar_positions": 167, "identity": "28.95%" }, { "cls_id": "homologset.agr.MGI:1931627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43320-1", "uniprot_id": "FGF16_HUMAN", "id": "O43320-1", "name": "Fibroblast growth factor 16", "aln": "--------------------------------------------------------------------------------------------MAEVGGVFASLDWDLHGFSSSLGNVP--------------LADSPGFLNERLGQIEGKLQ----------------------------------------------------------------------------------RGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPR------------------EGYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFHYR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ESL8-1", "uniprot_id": "FGF16_MOUSE", "id": "Q9ESL8-1", "name": "Fibroblast growth factor 16", "aln": "--------------------------------------------------------------------------------------------MAEVGGVFASLDWDLHGFSSSLGNVP--------------LADSPGFLNERLGQIEGKLQ----------------------------------------------------------------------------------RGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPR------------------EGYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFRYR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54769-1", "uniprot_id": "FGF16_RAT", "id": "O54769-1", "name": "Fibroblast growth factor 16", "aln": "--------------------------------------------------------------------------------------------MAEVGGVFASLDWDLQGFSSSLGNVP--------------LADSPGFLNERLGQIEGKLQ----------------------------------------------------------------------------------RGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELFGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPR------------------EGYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFRYR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2HXK8-1", "uniprot_id": "FGF16_DANRE", "id": "Q2HXK8-1", "name": "Fibroblast growth factor 16", "aln": "--------------------------------------------------------------------------------------------MAEVAGFLGSIDLDLQAFP-ALGNVP--------------LSDG---LNERLGLIEGRLQ----------------------------------------------------------------------------------RGSLTDFGHLKGILRRRQLYCRTGFQLEIFPNGTVHGTRQDHSRFGILEFISLAVGLVSIRGVDAGLYLGMNEKGELYGSKKLTAECVFREQFEENWYNTYASTLFKHADTGRYYYVALNKDGSPR------------------EGSRTKKHQKLTHFLPRPVEIEKIPQAYRELFQHR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDT9-1", "uniprot_id": "Q9VDT9_DROME", "id": "Q9VDT9-1", "name": "Fibroblast growth factor", "aln": "MRRNLRLDWRALALLGALLSFIIAWRGLVSAMPLMAMDNNLTDSSGSTNTSTSSTSKYNSTNNSNLFSNSYLQSDHSRSSLVPSAVSERSVNQPTNQSINAEFNQSLSTHPTAITSTPQTQTQTQIQSQYPSQAEDSDQLEEPLGFVISAMPNEHLAVLSRTERSIRHQNQQQQKKHHHHHQQQQQQQHQQQQPMSPADNNFIGSKSKRLSNPRSSLNINSSSSNTPISNLDRNERSTVPQSHLAWTSRKIQLYIKN-RILQILRDGVVNGTQDENSEFTILQRSTVDVGRIKLQSVATCLYLCMDACGVPYGSKDFTDDCVFNENMGLQNYNTYSSTYHSQAR--RVFYLALNGSGQPRRTQIPASRSLGKLSTYTNAITETVPQERVEQLIAKNFGANRVKHGVRQLCDTGKPLIELIDVARFKAPPHCSSNTSGSSSSISSSSSSSSKSSSNSSSSYVPVSAISSLSSISNSSQSESGHISSSLSGSSNSNSSSNSSSSNSSSNSSRPSGSKANKKKKPKCKPHEQEDTHNCQKRGGAGAGALRKLGPKAKRCKELREKAAAEKRAPPNCGKKNGARKNPTEAAKAVQQRPKGNIQHGGKKKPNKAGKQRQNGGKKQQQQQQHQLQQQPLQHQAKSISGGKRKHRKLDASTTTTMATSLGTPPSSHWESSSPLPAFSLSETSDRVERNVRMSSGEEQDQDNDQDQEQSDPGEQGEEETEGDGGSLEDASYEDSSSEAQGRSGAGGDDSLYYDFLCLQLIAMVLLRKRAIL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. ..:: .* .. :: ..* ::. *:* ** : . : . * . .** *: *** :. *:*: :*.*:**:.::*.* **: :: ** :.::.* : *** *: * :***.:* :***.*:: : ****:** ..:: * :*:*** .*.** .* :::. :::.: . .:: *:* ", "identical_positions": 56, "similar_positions": 79, "identity": "7.24%" }, { "cls_id": "homologset.agr.MGI:1931744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PM9-1", "uniprot_id": "UCK2_MOUSE", "id": "Q99PM9-1", "name": "Uridine-cytidine kinase 2", "aln": "---MAGDSEQTLQN--HQQ--PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGLSKRQTNGYLNGYTPSRKRQASESSSRPH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYG8-1", "uniprot_id": "UCK2_RAT", "id": "Q9QYG8-1", "name": "Uridine-cytidine kinase 2", "aln": "---MAGDSEQTLQN--HQQ--PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGLSKRQTNGYLNGYTPSRKRQASESSSRPH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZX2-1", "uniprot_id": "UCK2_HUMAN", "id": "Q9BZX2-1", "name": "Uridine-cytidine kinase 2", "aln": "---MAGDSEQTLQN--HQQ--PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGPSKRQTNGCLNGYTPSRKRQASESSSRPH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYM0-1", "uniprot_id": "UCK2A_DANRE", "id": "Q7SYM0-1", "name": "Uridine-cytidine kinase 2-A", "aln": "---MAGDSDSKLDN--HAENEHVDWQPFLIGVAGGTASGKSSVCGKIMELLGQNKIDHHQRQVAILSQDSFYRVLTPEQKAKALKGQFNFDHPDAFDNELIVKTLCEIMEGRTVQIPVYDFVTHSRKEE-TVTVYPADVVLFEGILMFYSQEIRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDFLNGGLTKR-LNGCLNGHTP-RKRHPSESSSRPH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZV79-1", "uniprot_id": "UCK2B_DANRE", "id": "Q7ZV79-1", "name": "Uridine-cytidine kinase 2-B", "aln": "---MAGDSETHLKD--RAENGHAVRQPFLIGVSGGTASGKSSVCEKIMELLGQNKIDRHQRQVVILSQDSFYRELTPEQKAKAVKGQFNFDHPDAFDSELIMKTLRDIIQGKTVHIPVYDFVTHSRKDE-FLTLYPADVVLFEGILMFYSQEIRDLFKMKLFVDTDPDTRLSRRVLRDISERGRELEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGFTKR-QNGFQNGHGTPRQRRTSESS-RPH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC99-1", "uniprot_id": "UCK_DROME", "id": "Q9VC99-1", "name": "Uridine-cytidine kinase", "aln": "MQDLRNADTLRLPNGDGAAANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRGADNT---VAIDLIVHHIGEILATTNSAQHSN---------TVRVAASSMKRDH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12084-1", "uniprot_id": "DAS2_YEAST", "id": "Q12084-1", "name": "Putative uridine kinase DAS2", "aln": "------MDRKAVEE-----------KRIVISIGGGHATG-----------VGAIALDLQN------TFKSLYNSIN--IRVINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDP-------IDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPSTNENLGRAVLVDGIVKAIEDTKSQIEGNNTNNKIRPRLWDFEAETMDLEKDRYYDLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . ::*.:.** *:* :* :* : : .*:*. :. :. .. :: : . :.: ..: :: : . . * :. . *:::. * :* .:.:: ::*:*:*:*.*.** : :. ..:* ::.:*: .::* :::: **:.:**:*** :* * :: **: * : . * . . * : ", "identical_positions": 37, "similar_positions": 89, "identity": "13.45%" }, { "cls_id": "homologset.agr.MGI:1931749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8L5-1", "uniprot_id": "D3Z8L5_RAT", "id": "D3Z8L5-1", "name": "Pumilio homolog 1", "aln": "-----MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGRSQDDAMVDY---FFQRQH----------------------------------------------------GEQLGGGGSGGGGYNTSKHRWPTG-----------DNIHAEHQVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDG-----PKGIFLGDQWRDSAWGT------SDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDE--------------------NDK-GEKKNKGAFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPGNCQSSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVG-----------------------LFDYNSQQQLFQRPN----------------ALAVQQLTAAQQQQ--------------------------------------------------YALAAAHQPHIG-LAPAAF--VPNPYIISAAPPGTDPYTAGLAAAATLGPAVVP-----HQYYGVTPWGVYPASLFQQQAAAAAAATNSAT---------------------QQSAPQAQQGQQQVLRGGASQRPLTPNQNQQ-----GQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYD----QTGALVVNAGARNGLGAPVRLVAPAPVIISSSA------AQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPSNNLA--SSSFYGNNSLSSNSQSS--SLFSQGSAQPANTSLGFGS------SSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLAPIGH------SFYNSLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNG----SGRYIS---------AAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRN-----NRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATAAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSHEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPED------KSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCT------MNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRK-YTYGKHILAKLEKYYMKNG-------------------------------------------------------------------------------------VDLGPICGPPNGII--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U78-1", "uniprot_id": "PUM1_MOUSE", "id": "Q80U78-1", "name": "Pumilio homolog 1", "aln": "-----MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGRSQDDAMVDY---FFQRQH----------------------------------------------------GEQLGGGGSGGGGYNTSKHRWPTG-----------DNIHAEHQVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDG-----PKGIFLGDQWRDSAWGT------SDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDE--------------------NDK-GEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPGNCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVG-----------------------LFDYNSQQQLFQRPN----------------ALAVQQLTAAQQQQ--------------------------------------------------YALAAAHQPHIAGLAPAAF--VPNPYIISAAPPGTDPYTAGLAAAATLGPAVVP-----HQYYGVTPWGVYPASLFQQQAAAAAAATNSAT---------------------QQSAPQAQQGQQQVLRGGASQRPLTPNQNQQ-----GQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYD----QTGALVVNAGARNGLGAPVRLVAPAPVIISSSA------AQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPSNNLA--SSSFYGNNSLSSNSQSS--SLFSQGSAQPANTSLGFGS------SSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLAPIGH------SFYSSLSYSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNG----SGRYIS---------AAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRN-----NRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATAAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSHEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPED------KSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCT------MNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRK-YTYGKHILAKLEKYYMKNG-------------------------------------------------------------------------------------VDLGPICGPPNGII--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14671-1", "uniprot_id": "PUM1_HUMAN", "id": "Q14671-1", "name": "Pumilio homolog 1", "aln": "-----MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGRSQDDAMVDY---FFQRQH----------------------------------------------------GEQLGGGGSGGGGYNNSKHRWPTG-----------DNIHAEHQVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDG-----PKGIFLGDQWRDSAWGT------SDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDE--------------------NDK-GEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPGNCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVG-----------------------LFDYNSQQQLFQRPN----------------ALAVQQLTAAQQQQ--------------------------------------------------YALAAAHQPHIG-LAPAAF--VPNPYIISAAPPGTDPYTAGLAAAATLGPAVVP-----HQYYGVTPWGVYPASLFQQQAAAAAAATNSAN---------------------QQTTPQAQQGQQQVLRGGASQRPLTPNQNQQ-----GQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYD----QTGALVVNAGARNGLGAPVRLVAPAPVIISSSA------AQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPNNNLA--SSSFYGNNSLNSNSQSS--SLFSQGSAQPANTSLGFGS------SSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLTPIGH------SFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNG----SGRYIS---------AAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRN-----NRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQ--NEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPED------KSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCT------MNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRK-YTYGKHILAKLEKYYMKNG-------------------------------------------------------------------------------------VDLGPICGPPNGII--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IWL6-1", "uniprot_id": "A0A0R4IWL6_DANRE", "id": "A0A0R4IWL6-1", "name": "Pumilio homolog 1", "aln": "-----MSVACVLKRKAVLWQDSFSPHLRLPPPDRPLPSMPVVLSAAG---HTPQPGPSPQAPAPTQG---------AGRSQDDAMVDY---FFQRQH----------------------------------------------------GDQP--------GYNNCKHRWPTG-----------DNIHADNQVRSMDELNHDFQALALEGRAMGEQLLTGKKFWETDDSGKDG-----PKGIFL-DQWRDSAWGA------SDHSVSQPIMVQRRPGQGFHGVGEAGSVLSPRSESGGLGVSMVEYVLSSSPAEKMDSCLRKGAYGPRDSEADD--------------------PEKRVEQKPKTTFDPERKELKETEPDVLDNPNGLPNQNGLDVDVKDFSRTPGNCPPTGQEVELGGPEMVGG---------AGPKPAEEFSNVETQNVTLDPMESVSMETLQFEYPGGQLPLDSTAATVG-----------------------LFDYNSPQQLFQRPN----------------ALAVQQLTAAQQQQ--------------------------------------------------YALAAAQQPHIG-LAPAAF--VPNPYIISAAPPGTDPYAAGLAAAATLGPAVMP-----PQYYGVTPWGVYPANLFQQQAATP---SNSAN---------------------QQSAAQNQQNQQQVMRAGGNQRPLTPSQGQQ-----GQQTEQLVAAAAVNSALAFGQGLAAGVPGYPVLAPAAYYD----QTGALVVNTGAR---GGPVRLMAPASVIISPS---------AAVAAAAASAGGANAGLGGGASGAFRALSSQQ---APGQQGSGALG--GSSFYGSGSPSSSSQSS--SLFSQGSAQPGNTSLGFNAN----PTSSLGATLGAALGGFGTAVANSSS-SGSRRDSLTGSSDLYKRTASSLTPIGHG-----AFYNGLSFSSSPGPVGMPLPNQGPSHSLTPPPSLSTHGSSSSLNLGGLTNG----SGRFIS---------AAPGAEAKYRSATTGSSLFSPSSQLFPSSRLRYGMSDVMPSGRSRLLEDFRN-----NRYPNLQLREIAGHVMEFSQDQHGSRFIQLKLERASPAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLDQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPHALQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPEQTLSILEEIHQHTEQLVQDQYGNYVIQHVLEHGRAED------KSKIVSEIRGNVLGLSQHKFASNVVEKCVTHSLRAERAMLIDEVCS------MADGPHSALYTMMKDQYANYVVQKMIDVAEPTQRKIVMHKIRPHIATLRK-YTYGKHILAKLEKYYMKNG-------------------------------------------------------------------------------------VDLGPLCAPPNGIM--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25822-1", "uniprot_id": "PUM_DROME", "id": "P25822-1", "name": "Maternal protein pumilio", "aln": "MKFLGGNDDRNGRGGVGVGTDAIVGSRGGVSQDAADAAGAAAAAAVGYVFQQRPSPGGVGVGVGGVGGGVPGVGAVGSTLHEAAAAEYAAHFAQKQQQTRWACGDDGHGIDNPDKWKYNPPMNPANAAPGGPPGNGSNGGPGAIGTIGMGSGLGGGGGGGAGGGNNGGSGTNGGLHHQSMAAAAANMAAMQQAAALAKHNHMISQAAAAVAAQQQHQHPHQQHPQQQQQQQQAQNQGHPHHLMGGGNGLGNGNGLGIQHPGQQQQQQQQQQQQQHPGQYNANLLNHAAALGHMSSYAQSGGSMYDHHGGAMHPGMNGGMPKQQPLGPPGAGGPQDYVYMGGQTTVPMGAAMMPPQNQYMNSSAVAAANRNAAITTSTAKKLWEKSDGKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVPPPSRAYAHGGASDTSNS-GNAGILSPRDSTCAKVVEYVFSGSPTNKDSSLSGLEPHLRNLKFDDNDKSRDDKEKANSPFDTNGLKKDDQVTNSNGVVNGIDDDKGFNRTPGSRQPSPAEESQPRPPNLLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPPMMNGVGGGMPMAAQSPMLNHQAAGPNHMESPGNLLQQQNFDVQQLFRSQNPGLAAVATNAAAAAAAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMAAASQQFLAAQQQAQNAAYAAQQATSYVINPGQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPSQQGAENQPYQVIPAFLDHTGSLLMGGPRTGTPMRLVSPAPVLVPPGATRAGPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVAAAANAVNSTVAQAAAAAAAAAAARGKWPGAMSGAASGAYGALGAGNASASPLGAPITPPPSAQSCLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFG----SNSSIFSNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRN-----QRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQ--QEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQHVLEHGKQED------KSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCT------FNDN---ALHVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRK-YTYGKHINAKLEKYYMKITNPITVGTGAGGVPAASSAAAVSSGATSASVTACTSGSSTTTTSTTNSLASPTICSVQENGSAMVVEPSSPDASESSSSVVSGAVNSSLGPIGPPTNGNVVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07807-1", "uniprot_id": "PUF3_YEAST", "id": "Q07807-1", "name": "mRNA-binding protein PUF3", "aln": "-------MEMNMDMDMDMELASIVSSLSALSHSNNNGGQAAAAGIVNGGAAGSQQIGGFRRSSFTTAN--------------------------------------------------------------------------------------------------------------------EVDSEILLLHGSSESSPIFKKTALSVGTAPPFSTNSKKFFGNGGN--------------------------------YYQYRSTDTASLSSASYNNYHTHHTAANLGKNNKVNHLLGQYSASIAGPVYYN-----------GNDNNNSGG---------------------EGFFEKFGKSLIDGTRELESQDRPDAVNTQSQFISKSVSNASLDTQNTFEQNVESDKNFNKLNRN-------------TTNSGSLYHSSSNSGSSASLESENAHYPKRNIWNVANTPVFR--------------------------------------------------------------------------------------------------------------------------------------------------------------PSNNPAAVGATNVALPN---------------------------------------------------------------QQDGPANNNFPPYMN---------------------GFPPNQFHQGPHYQN-----------FPNYLIGSPSNFIS--QMISVQIPANEDTEDSNGKKKKKANRPSSVSSPSS------PPNNSPFPFAYPNPMMFMPPPPLSAPQQQQQQQQQQQQEDQQQQQQQE-----------------------------------------------------------------------------------------------------------NPYIYYPTPNPIPVKMPKDEKTFKKRNNKNHPANNSNNANKQANPYLENSIPTKN---------------TSKKNASSKSNESTANNHKSHSHSHPHSQSLQQQQQTYHRSPLLEQLRNSSSDKNSNSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYACRVIQKALEYIDSNQR--IELVLELSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYLIQDQYGNYVIQYVLQQDQFTNKEMVDIKQEIIETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILMIKDQFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKSNSLGNRHLASVEKLAALVEN------------------------------------------------------------------------------------AEV-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . . ... . . . : . :. * : ::. . : . .. . : *. .. . .. * . . : :. : . . :. . .. . . . *. . *.. : : : .. * : :.* . ** :: : . . . : .* * : . . : . . : * : . . . : . . . .. * . . :*.. .: .: . .. : : : :. : . . ** ***::** : .*:.*::: .* :**.:********* :* :..:*::::*.** * .* ***************: ** :* :.:*:: .*:****.********* * .:*: *:* **.. **: :********:**.** : * **:.::.*::: ****.********:**. .:: .**:*:::. *:**********:**::.: : *. :: : .:*: *:**********.: :. : :: :*.:: . : .: *:***:****:**:::*:* * :: **.:: *.* : *:: *.:** .: ", "identical_positions": 164, "similar_positions": 221, "identity": "10.51%" }, { "cls_id": "homologset.agr.MGI:1931751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80U58-1", "uniprot_id": "PUM2_MOUSE", "id": "Q80U58-1", "name": "Pumilio homolog 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN---------HDFQALALES--------------RGMG------------------ELLP------------------------TKKFWEPDD------STKDG------QKGIFLGDDEWRETAWGTS--HHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADK------LDSRFRKGTFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQ-DDEDS-KINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPS------------TNPPEGLG-------PLPNPTANKPLVEEFSNPETQNLDAMDQVG-LDSLQFDYPGNQVPMDSSG-----ATVGLFDYNSQQQLFQRTSALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAASNTANQQAASQAQ-PGQQQVLRPGAGQRPITPSQGQQ--GQQAESLAAA--ANPTLAFGQSLAAGMPG-YQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSTAAQAAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQ---QQQQQQPSTNLQSNSFYGS-SSLTNSSQSSSLFSHGPGQPG-SASLGFGSGS-SLGAAIG----SALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSS-SLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHS-LTPPPSL-SSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQIVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQ------NDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRK-YTYGKHILAKLEKYYLKNS-------------------------------------------------------------------------------------PDLGPIGGPPNGML--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8F9-1", "uniprot_id": "A0A0G2K8F9_RAT", "id": "A0A0G2K8F9-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN---------HDFQALALES--------------RGMG------------------ELLP------------------------TKKFWEPDD------STKDG------QKGIFLGDDEWRETAWGTS--HHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADK------LDSRFRKGTFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQ-DDEDS-KINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPS------------TNPPEGLG-------PLPNPTANKPLVEEFSNPETQNLDAMDQVG-LDSLQFDYPGNQVPMDSSG-----ATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAASNTANQQAASQAQ-PGQQQVLRPGAGQRPITPSQGQQ--GQQAESLAAAAAANPTLAFGQSLAAGMPG-YQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQ---QQQQQ-PSTNLQSNSFYGS-SSLTNSSQSSSLFSHGPGQPG-SASLGFGSGS-SLGAAIG----SALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSS-SLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHS-LTPPPSL-SSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEIVQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALANRIRGHVLPLALQMYGCRVIQKALESISSDQQ--SEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQ------NDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRK-YTYGKHILAKLEKYYLKNS-------------------------------------------------------------------------------------PDLGPIGGPPNGML--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TB72-1", "uniprot_id": "PUM2_HUMAN", "id": "Q8TB72-1", "name": "Pumilio homolog 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN---------HDFQALALES--------------RGMG------------------ELLP------------------------TKKFWEPDD------STKDG------QKGIFLGDDEWRETAWGAS--HHSMSQPIMVQRRSGQGFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADK------LDSRFRKGNFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQGDDDDS-KINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPN------------TNPSEGLG-------PLPNPTANKPLVEEFSNPETQNLDAMEQVG-LESLQFDYPGNQVPMDSSG-----ATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTASQQAASQAQ-PGQQQVLRAGAGQRPLTPNQGQQ--GQQAESLAAAAAANPTLAFGQGLATGMPG-YQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGG-TASSLTGSTNGLFRPIGTQPPQQ---QQQQP--STNLQSNSFYGS-SSLTNSSQSSSLFSHGPGQPG-STSLGFGSGN-SLGAAIG----SALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSS-SLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHS-LTPPPSL-SSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQ------NDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRK-YTYGKHILAKLEKYYLKNS-------------------------------------------------------------------------------------PDLGPIGGPPNGML--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NFM3-1", "uniprot_id": "A0A8M1NFM3_DANRE", "id": "A0A8M1NFM3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIPCSILGMNDVPWQETQCGTLHTNGAPETGGVRVHAGCPLATVGGARQVPGGVHPLQG----MANPNPCTQPLLSGRSQDDATVGYFFQRQPGEQMGGCTGNKHRWP-TGDGNHVDQLRSVDEMN---------YNFQALALES--------------RGMG------------------ELLP------------------------AKKLWESDE------LAKDG------RKAMLVG-EEWRENAWSSS--HHALSQPIMVQKRPGQGYNGTGETSSVLSPRSEGGGLGVSMVEYVLSSSPGDK------MDGRYRNGGYGEADADPDGREKGESKEKSSPFEENKSPEMKVGDEGDTSKANARGLLNGMDRDCKDFNPTPGSRQASPTEAVERLGPSQAGL-----EIMVQHHQHTL-------QAPNPVTNKPPPEDFQSQEAQNMGGMEQQAGLEALQFDYGGNQIQLDSSG-----AAVGLFNYDSQQQLFQRSSHLTVQQLNAAQQQQYALAAAQQQHLG------LAP-AFVPNPYIINAAPPGADPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQATAAASHSANQQASSQG--PGQQ-VIRAGSNQRPLTPGQSQQ--SQQ-ESLAAAA-TNPTLAF-----PGMSG-YQVLAPAAYYDQTGALVMGPGTRTGLGGPVRLVQ-TPLLINPAAAQAAAAASVSG-SGNSMSGPANGLYRSMACQQPQQPQPQQQLPPPSSGLPSNSFYGS-GSVAPSSQSSSLFSHTSAAPPPSTSLGFSSTSGSLGVGLG----SALGAFGSSVSSSTNSSAVRRDSLLASSELYKRGGGGSLTPIGQSFYNSLGYSSSPSPIGL-----TPGHSPLTPPPSLPSSHGSSSSIHLGGLPNGSGRYISAAPGAEAKYRSSGSTSSLFSSSSQLFPPPRARYSRSDVMPSGRSRLLEDFRNNRFPNLQLRDLPGHMVEFSQDQHGSRFIQQKLERATSAERQMVFGEILQAAYQLMTDVFGNYVIQKFFEFGSADQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISDIVRELDGHVLKCVKDQNGNHVVQKCIECVQPQALQFIIDAFQGQVFVLSTHPYGCRVIQRILEHCTQEQTLPILEELHQHSEQLGQKYQGVSLEMTPKTYYTVSSDALFKDQYGNYVIQHVLEHGRPED------KSKIVAEVRGKVLALSQHKFASNVVEKCVIHSSRAERALLIDEVCCQ------KDGPHSALYTMMKDQYANYVVQRMIDMAEPAQRKIIMHKIRPHIATLRK-YTYGKHILAKLEKYYMKSG-------------------------------------------------------------------------------------SDLGPIGGPTNGLM--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25822-1", "uniprot_id": "PUM_DROME", "id": "P25822-1", "name": "Maternal protein pumilio", "aln": "MKFLGGNDDRNGRGGVGVGTDAIVGSRGGVSQDAADAAGAAAAAAVGYVFQQRPSPGGVGVGVGGVGGGVPGVGAVGSTLHEAAAAEYAAHFAQKQQQTRWACGDDGHGIDNPDKWKYNPPMNPANAAPGGPPGNGSNGGPGAIGTIGMGSGLGGGGGGGAGGGNNGGSGTNGGLHHQSMAAAAANMAAMQQAAALAKHNHMISQAAAAVAAQQQHQHPHQQHPQQQQQQQQAQNQGHPHHLMGGGNGLGNGNGLGIQHPGQQQQQQQQQQQQQHPGQYNANLLNHAAALGHMSSYAQSGGSMYDHHGGAMHPGMNGGMPKQQPLGPPGAGGPQDYVYMGGQTTVPMGAAMMPPQNQYMNSSAVAAANRNAAITTSTAKKLWEKSDGKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVPPPSRAYAHGGASDTSNSGNAGILSPRDST---CAKVVEYVFSGSPTNKDSSLSGLEPHLRNLKFDDNDKSRDDKEKAN-----SPFDTN---GLKK-DDQVT---NSNGVVNGIDDD-KGFNRTPGSRQPSPAEESQPRPPNLLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPPMMNGVGGGMPMAAQSPMLNHQAAGPNHMESPGNLLQQ-QNFDVQQLFRSQNPGLAAVATN--------AAAAAAAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMAAASQQFLAAQQQAQNAAYAAQQATSYVINPGQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPSQQGAENQPYQVIP--AFLDHTGSLLMG-GPRT--GTPMRLVSPAPVLVPPGATRAGPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVG---GLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVAAAANAVNSTVAQAAAAAAAAAAARGKWPGAMSGAASGAYGALGAGNASASPLGAPITPPPSAQS-CLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIFSNPLAIPG----TAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQ--QEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQL------------------------IQDQYGNYVIQHVLEHGKQED------KSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTF------NDN---ALHVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRK-YTYGKHINAKLEKYYMKITNPITVGTGAGGVPAASSAAAVSSGATSASVTACTSGSSTTTTSTTNSLASPTICSVQENGSAMVVEPSSPDASESSSSVVSGAVNSSLGPIGPPTNGNVVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07807-1", "uniprot_id": "PUF3_YEAST", "id": "Q07807-1", "name": "mRNA-binding protein PUF3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMNMDMD---------------MDMELASIVSSLSALSHSNNNGGQAAAAG-------------IVNGGAAGSQ------QIGGFRRSSFTTANEVDSEILLLHGSSESSPIFKKT--------------ALSVGTAPPFSTNSKKFFGNGGNYYQYRSTDTASLSSA----------------------------SYNNYHTHHTAANLGKNNKVNHLLGQYSASIAGPVYYNGNDNNNSGGEG----------FFEKFGKSLIDGTRELESQDRPDAVN---------------------------------TQSQFISKSVSNASLDTQNTFEQNVESDKNFNKLNRNTTNSGSLYHSSSNSGSSASLESENAHYP----------------------------------------------------KRNIWNVANTPVFRPSNNPAAVG-----------ATNVALPNQQDGPANNNFPPYMNGFPPNQFHQGPHYQNFPNYLIGSPSN----FISQMISVQIPANEDTEDSNGKKKKKANRPSSVSSPSSPPNNSPFPFAYPNPMMFMPPP-----PLSAPQQQQQQQQQQQQEDQQQQQQQENPYIYYPTPNPIPVKMPKDEKTFKKRNNK---------------NHPANNSNNANKQANPYLENSIPTKNTSKKNASSKSNESTANNHKSHSHSHPHSQSLQQQQQTYHRSPLLEQLRNSSSDKNSNS---NMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYACRVIQKALEYIDSNQR--IELVLELSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYL------------------------IQDQYGNYVIQYVLQQDQFTNKEMVDIKQEIIETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILMIKDQFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKSNSLGNRHLASVEKLAALVEN------------------------------------------------------------------------------------AEV-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . ... . : * ..:. .: *. : : . . **: . . * :. : * * . *. : . * : . : .. ... . .*:: : *: : : : : . . ..* : : . : . : :. : ::* .: ... :* * * . .. . . . . * :. . .. .. . . .. .:.. . .:.. . . . :. . . . . . . .. . :. . .*: : .: . . : . *. :. *. *:.*:*: .* :**.:*********::* :..:*::::*.** * .* .***************: ** :* :.:*:: *:****.********* *..:*: ::* **.. **: :********:**.** : * **:.:: *::: ****.********:**. : *: .**:**::. * .:*********:**::.: : *. :: : .:*: *:**********.: :.:: :: :*.:: : .: *:***:****:*::::::* * :: **.:: *.* : *:: *.:** ..: ", "identical_positions": 162, "similar_positions": 242, "identity": "10.04%" }, { "cls_id": "homologset.agr.MGI:1931787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQC5-1", "uniprot_id": "SCYL1_MOUSE", "id": "Q9EQC5-1", "name": "N-terminal kinase-like protein", "aln": "MW-FFARDPVRDFPFELSPEPPEGGPPGPWILHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEK-CLHIVTEAVTPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGN----GGGPPSKGIPELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVFNGSLPRAAALRNPGKIPKSLVTHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDSFPEDFCRHKVLPQLLTA-FEFGNAGAVVLTPLFKVGKSLRAEEYQEKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVTHGFLDTNPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDDQGPIRCNTTVCLGKIGSYLSASTRHR--VLTSAFSRATKDPFAPSRVAGVLGFAATHNLYSMDDCAHKILPVLCGLTVDPEKSVRDQAFKTIRSFLSKLESVSE--DPTQLAEVEKDVHAASSPGTGGAAASWAGWAVTGVSSLTSKLIRAHPT----PVPSDTTVPQRPVPEGNPAPAPALAQAIPATSGHWETQE-DKDTAEDSATADRWDDEDWGSLEQEAE---------------SVLAQ---QDDWSAKGQGSRAGQINHPDHKS---LESHWSS-WEVEG-SWDQG-------------------WQE----PSSVEPPP---------------EGTRLASEYNWGGAE-PSDKGDPFAALSVRPSAQP----RPDPDSWG-EDNWEGLE-AESRQVKAELARKKREE----RRREMEAKRAEKKTTKGPMKLGARKLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M9F8-1", "uniprot_id": "SCYL1_RAT", "id": "Q5M9F8-1", "name": "N-terminal kinase-like protein", "aln": "MW-FFARDPVRDFPFELNPEPPEGGPPGPWVLHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEK-CLHIVTEAVTPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDKAGEWKLGGLDYMYSAQGN----GGGPPNKGIPELEQYDPPELADSSSRAVKEKWSADMWRLGCLIWEVFNGSLPRATALRNPGKIPKSLVTHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDSFPEDFCRHKVLPQLLTA-FEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSSTDRAMRVRLLQQMEQFIQYLDEPTVNTQIFPHVTHGFLDTNPAIREQTVKSMLLLAPKLSETNLNVELLKHFARLQAKDDQGPIRCNTTVCLGKIGSYLSASTRHR--VLTSAFSRATKDPFAPSRVAGVLGFAATHNLYSMDDCAHKILPVLCGLTVDPEKSVRDQAFKTIRSFLSKLESVSE--DPTQLAEIEKDVHAASSPGTGGAAASWAGWAVTGVSSLTSKLIRTHPT----PVPSEAAVPQRPVPEGDPAPAPAPASATPATSGHRETQEEDKDAAEDSATADRWDDEDWGSLEQEAE---------------SVLAQ---QDDWSTKGQGNRAGQVSHSDHKS---LDSHWSS-WEVEG-SWDQG-------------------WQE----PSSVEPPP---------------EGTRLASEYNWGGAE-PSDKGDPFAALSVRPSTQP----RPDPDSWG-EDNWEGLE-AESRQVKAELARKKREE----RRREMEAKRAEKKATKGPMKLGARKLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KG9-1", "uniprot_id": "SCYL1_HUMAN", "id": "Q96KG9-1", "name": "N-terminal kinase-like protein", "aln": "MW-FFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEK-CLHVVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGN----GGGPPRKGIPELEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTA-FEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDEQGPIRCNTTVCLGKIGSYLSASTRHR--VLTSAFSRATRDPFAPSRVAGVLGFAATHNLYSMNDCAQKILPVLCGLTVDPEKSVRDQAFKAIRSFLSKLESVSE--DPTQLEEVEKDVHAASSPGMGGAAASWAGWAVTGVSSLTSKLIRSHPT----TAPTETNIPQRPTPEGVPAPAPTPVPATPTTSGHWETQEEDKDTAEDSSTADRWDDEDWGSLEQEAE---------------SVLAQ---QDDWSTGGQVSRASQVSNSDHKSSKSPESDWSS-WEAEG-SWEQG-------------------WQE----PSSQEPPP---------------DGTRLASEYNWGGPE-SSDKGDPFATLSARPSTQP----RPD--SWG-EDNWEGLE-TDSRQVKAELARKKREE----RRREMEAKRAERKVAKGPMKLGARKLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3D6-1", "uniprot_id": "E7F3D6_DANRE", "id": "E7F3D6-1", "name": "N-terminal kinase-like protein", "aln": "MWSFFARDPIKDFNYELLPENQE--KSGIWTLSRGKRKSTGEPVSVFVYEVSQGTEEQTQLAKAAFKRTKTLRHPNILSYVDGLETEK-SLYIVTEPVTPLAAHLKLQAEKGGASDLEVSWGLHQIVKALSFLVNDCHLNHNNLGMWAVFVDRAGEWKLGGLDHVTSEQGDS--ITLPPPKVINPDLERYDPPESPNSGG----EKWTGDVWRLGCLIWEVFNGSLPRASSLRSLGKIPKQLVPHYCELVGANPKIRPNPARFLLNCRSPGGFMNNSFVESCLFLEEIQIKEPAEKQQFFQDLSENLDSFPEDFCKHKVLPQLLTA-FEFGNAGAVVLTPLFKVGKYLSAEEYQQKIIPVIVKMFSSTDRAMRIRLLQQMEQFIQYLNEAAVNSQIFPHVVHGFTDTNPAIREQTVKSMLLLAPKLNETNLNQELMRHFARLQARDDQGPIRCNTTVCLGKIAPYLNAGMRQR--VLISAFSRATKDPFPASRAAGVLGFAATHQYYSVAESANRILPTLCTLTVDPDKNVRDQAFKAIKSFLSKLETVSE--DPSKLTEIEKDVTAAG--QTGGSAATWAGWAVTGVSSLTSKLIRNAPAGSEAPSAENTSSPQPAAGSVNTNTADKAEEMKTQTSSGIKSETSNEETGDTD--GDRWDEEDWGSLEDPEK---------------VQTDPDDWQSNWSSVSSTQKKSNVGRKSSEAVKKQSSDWSSGWDADD-SWSNEKDADGQGQSSPADEGWGNDWDEDGTLAESFAPTPRIKSSAATKSASSAQDGVRLASDYNWDGMEGKSTTSDLLSSVSQRSATKSDGWDADSAGDWGTEDNWESLD-GEQGLSKAELAKKKREE----RRKELEAKRAERKAAKGPLKLGARKLD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAH7-1", "uniprot_id": "Q9VAH7_DROME", "id": "Q9VAH7-1", "name": "N-terminal kinase-like protein", "aln": "MWSFFSRDSSKDFPYDIGEPVGGFDQYSIWTLHKAKRKTTLEEVSVFVYDIRSGSDTKCELAKAALKRLKTLRHPSILQYLDSLETDK-MLYVATEAVDPLGTYFSKLGSDNVQKGLYLAWGIFQITRALSFLNNDGNLRHNNVSAWSVFVNASGEWKLGSLEYVSAADGN-----PMPPAKIPVTLEVYDSPEKNDPSKLKAATKCSVDMWGLGCLVWEAFNGVLKQRSNLKDIEHIPKSLQSLYCELVGASPSNRPNPADIITRCRKPGGFFKNDLVDTLLFLEEIQIKDKAEKNRFFSGLTTHLDNFPDNVCRHKILPQLITA-YEYGDAGSAVLAPMFKLGKLLDEVEYQKRIVPCVVKLFASTDRVTRSRLLQQLDLFIAHLQPQVVNDQIFPQVAHGFLDTNATIREQTVKSIIHLAPKLNYNNLNVEVLRHFARLQARDDQGGIRTNTTVCLGKIAPHLHPQVRQR--VLVSAFIRAMRDPFPPARVAGVLALAATQQYFLLSEVANRVLPSLCSLTVDPEKTVRDPAFKTIRGFLGKLEKVSE--DPSLRETMEADVHTAT-PSIGNAAATWAGWAVTAVTAKFYRSQSDSSR--PRPPLTGRNLSKPASLEQPSSSSLSTTTSSVTSMTSLEHESNDTSASASDYGNNDWDNENWGEMDTSQDPSSPLAASSNNGALMAANALSEVRDGWDNEEWGSLEEDPCEEEEQAEQEQQQQQLARQSISSTSSSQPNQRPLLPHQQQYPHQQQLQQHELNDLIEPLAKLNSHVTSPSKQSMLRPKELPNLSSSNTSPTSATANCNNISPPSSHLNNSTHN---ANWNSDSWA-DGEFEPLDESGFGNAKLDEARRKREEKKLQRQRELEARRAQR--ASGPMKLGAKKL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12453-1", "uniprot_id": "CEX1_YEAST", "id": "Q12453-1", "name": "Cytoplasmic export protein 1", "aln": "MNFSSIFKSISNFQFPYTIEETAITETALWQCFDGTRKADSLPVTVFKAKRSP---ENESLILNAVHKSKILKIPGLCTVLETFDSDPQSTFIVTERVVPFPWDNLGSLSQN---KFGVELGISQLLATLGFLKN---FVLGTLSKDSVFINIKGEWVLFGLELCSSKEGLSAFEFASRARSYYNIIGSQLPCEDPNTIDSMGLGLLIKSLMAPSCLPKDWIVNVNMISDGKITIENFRKRLEN--TETWRSNPLINFYQELRELHIKDPQGKLVVMSNLENLYLESREIFRNLTPGMIENFIIPELCEIIKLLMTQSISSAASPIGMNFNASHKLVPFLAIVLDLTSETNTFPVGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLSKSEISSRIYPHFIQGLTDSDATLRLQTLKTIPCIVSCLTERQLNNELLRFLAKTQVDSD-VEIRTWTVIIISKISTILSTSVGNRSNILATAFTKSLKDPQVKPRLAALYGLEKSIELFDVNTIANKILTVIAPGLLDKSPIVRGRAKILFEEYLEKLEKEAQLIQTNDSTADSEDVKDIDFENYGCDEEDMNKEDNLLAAQFLNNLRLNSPS-----ATTPSNITESEIDSAQDGSGWDDLSDTDGFITNGTTESFDETTNPVTTASTPKLFGKPIKINKSWN------------------------DELNDDGWIQDESGPSKVPQKHTRPQNSTLAKSIAPSSRLSIKKKK------------------------TTILAPRN------------------IASNSTVTTKSSLSNKTARSKPISSIRGSVTK----KGNVDGWDDDGDSDSWDTNW----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .. :* : . * . :*: *::* . : .: *.:: * *: *.: :: :::: .:.** * *: . . : *: *: :*.** * : ..: :**:: *** * .*: : :* . : . * :. .: .** : : . :: * * * :.* . . : * * : *:**. :* : . : * : . . :.: . . ::. : * : :. : : :.: * .** * ** : :* *. :. :*:*:. :*: *::.::* **:*:: :.. *. :** *:::.:*: *. .: ** *.: :.**.. * . :* :* :** :: :** .* *.: .: : : : : *:::*. :. :* . **. * :. :* ***. :: :.. . ** * .: . . .: . .. : : : . .:: . . . . . : .. .. : :.. . . . . :. . .* :.: : : ", "identical_positions": 93, "similar_positions": 211, "identity": "10.4%" }, { "cls_id": "homologset.agr.MGI:1931797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V1H1-1", "uniprot_id": "CKAP2_MOUSE", "id": "Q3V1H1-1", "name": "Cytoskeleton-associated protein 2", "aln": "MAESRKRFLGRAARNPLPVTRDLQLPPTRRDQPAFREQRKQKLKEYLLIRKTVFPYKQEN---QISRDQKMITSEDRVQEGKKVVKLKTEVADKENIE--------STVEKNCIPLK-AGEVTSS----EIHNSKDNVQAVQLLSTRDDLPGQTVTLDPACHHKDN-KKMQMTAEKPKQDSNVSKKRVLGYYHGQIVQSKINSFRKLPSVKGESLTTTKKLPTTVSKAMKAQSEPANTVSVKASTTAAATKFADAKPVSTASKDT-LVRPPIRSLHSSSHG----AAKQGLSRPLANVTVRKGMLDKESHRSEPVVSVVKAGSSQ------APSRSIASKDAARTDS-SNTRLMVKPKDTDQRRYTIAGASVH-RSAQLKDTTAERKAQMTEWRTGKGKGLKRPPHSVVTQAEPKGQSENPVGSFWTTMAEEDEQRLFTEKVNKTISECLNLINEGCPKEEILATLNDLIHNIPDAKKLVKYWICLVRIEPITSPIENIISIYEKAILAGAQPIEEMRHIIIDILTTKSQEKVNLGENIEEAHATKEPIQEVNADAN---VGSGKPGEENEHHG--KVEVYEDDQDNKIKDP--DLTTPDSKTEAGCIIRYNVSSTPRLQSMKK-MQHD-KNSTLKELKFLTPVRRSRRIQDKTSRLPAMLKDHDPSVSSLEQLSELG--GDAFVCRPNAALCPLFFETDVAEEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPD0-1", "uniprot_id": "D3ZPD0_RAT", "id": "D3ZPD0-1", "name": "", "aln": "MAESRKRSLGRPARSTLRVPRDLQLPPTKRDQPAFREQRKEKLKEYLLIRKTTFPYKQEN---QISRDQKMVTSEDQVQEGKKVVKLKTEVADKENIG--------SIVEKNCVPLK-AEEVASS----ETHHPKGDVQAVQLLSTGADFPGQPVMLDQACHHKDS-AGTQVTAEKTKQDTNMSKKRVLGYYHGQIVQSKINSFRKLPSVKDESLAATKKLPTTVSKARKAHIEPGKAVSVRASNTAAATRSTDTNSGSALSKNT-LVRPPIRSLHSRTHGGTLGAVKQGLGGTLDSVTVRKESLEKESHRPEPVMSVVKTSSSQDTKRGKAPPRSIACKDVTRTNS-SNARLTGKSRDPDQRRYTIAGAAVL-RSAQPKDTTADRKAQMTDWRTGKGKGLKRPPHSEVTQAEPKRQNENAVGSFWTTMAEEDEQRLFTEKVNKTISECLNLINKGCPKEEILATLNDLIHNIPDAKKLVKYWICLVRIEPITSPIENIISIYEKAILAGAQPIEEMRHIIIDILTTKNQEKANLGENIEEAHATKEHIQEVNVETN---LGSGKPEEENEHHR--KVEVYEDNQDSKTEDPTNDLTTPDSKAEAGCLIRYNVSSTPRLQSMKK-TQHD-KNSTFKELKFLTPVRRSRRIQEKTLRLPDMLKDHDPSVSSLEQLSELG--GDAFVCRPNAALCPLFCETDVVEEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WWK9-1", "uniprot_id": "CKAP2_HUMAN", "id": "Q8WWK9-1", "name": "Cytoskeleton-associated protein 2", "aln": "-------------MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQ--PVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRD----TVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *.:******::* *.**:***::****:** *** *.***** . ****:::****:****.**:****::*****: : * *:*:*** : *::.* : *:.*.. *: :** * * .* : *. * * *:. *:*:** ***:*:.** *** *:************* .**.** ::****.:*:.** *.: * :: ** .... ::. : :: *: *::* ******** ** ::. :.***:. . .**:** :** :.:..:* **:.*** : .****.: :*. * ** :* *.. ****:* . * * **** *:*: :***::::*::***: *****:* *** ** *.*:.**********************:*:********:*****:**.******:***************. ************:****************** *:**** *.***.*****:*:: *:** ::**. : . :.. * *.: * .: *.:**.* :** *:.**::::.:.*:*:****:** ***:** *.* .**::**************:*:** :** ***** *.*******:*** ************ :: *:*.. ", "identical_positions": 372, "similar_positions": 174, "identity": "52.77%" }, { "cls_id": "homologset.agr.MGI:1931825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GZX3-1", "uniprot_id": "CHST6_HUMAN", "id": "Q9GZX3-1", "name": "Carbohydrate sulfotransferase 6", "aln": "------------------------------------------------------MWLPRVSSTAVTALLLAQT-FLLLFLVSRPGPS----------------------------------------------------------------------------------------SPAGGEARVHVLVLSSWRSGSSFVGQLFNQHPDVFYLMEPAWHVWTTLSQGSAATLHMAVRDLVRSVFLCDMDVFDAYLPWRRNLSDLFQWAVSRALCSPPACSAFPRGAISSEAVCKPLCARQSFTLAREACRSYSHVVLKEVRFFNLQVLYPLLSDPALN-LRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGTWVEADPGLRVVREVCRSHVRIAEAATLKPPPFLRGRYRLVRFEDLAREPLAEIRALYAFTGLSLTPQLEAWIHNITHGSGPGARREAFKTSSRNALNVSQAWRHALPFAKIRRVQELCAGALQLLGYRPVYSEDEQRNLALDLVLPRGLNGFTWASSTASHPRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9GZS9-1", "uniprot_id": "CHST5_HUMAN", "id": "Q9GZS9-1", "name": "Carbohydrate sulfotransferase 5", "aln": "---------------------------------MGMRARVPKVAHSTRRPPAARMWLPRFSSKTVTVLLLAQTTCLLLFIISRPGPS----------------------------------------------------------------------------------------SPAGGEDRVHVLVLSSWRSGSSFLGQLFSQHPDVFYLMEPAWHVWTTLSQGSAATLHMAVRDLMRSIFLCDMDVFDAYMPQSRNLSAFFNWATSRALCSPPACSAFPRGTISKQDVCKTLCTRQPFSLAREACRSYSHVVLKEVRFFNLQVLYPLLSDPALN-LRIVHLVRDPRAVLRSREAAGPILARDNGIVLGTNGKWVEADPHLRLIREVCRSHVRIAEAATLKPPPFLRGRYRLVRFEDLAREPLAEIRALYAFTGLTLTPQLEAWIHNITHGSGIGKPIEAFHTSSRNARNVSQAWRHALPFTKILRVQEVCAGALQLLGYRPVYSADQQRDLTLDLVLPRGPDHFSWASPD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GGK1-1", "uniprot_id": "A0A8I6GGK1_RAT", "id": "A0A8I6GGK1-1", "name": "Sulfotransferase", "aln": "------------------------------------------------------MRLPRFSSTVVLSLLIVQT-GILVFLVSRQMPS----------------------------------------------------------------------------------------SPAGRGEHVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWDALSQASAPALHMAVRDLIRSVFLCDMDVFDAYLPWRRNISDLFQWAVSRALCSPPVCDAFARGNISSEEVCKPLCATRPFGLAQEACSSYSHVVLKEVRFFNLQVLYPLLSDPALN-LRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGTWVEADPRLRVVSEVCRSHVRIAEVALHKPPPFLQDRYRLVRYEDLARDPLTVIRELYAFTGLGLTPQLQTWIYNITHGSGPGARREAFKTTSRDALSVSQAWRHTLPFAKIRRVQELCAGALQLLGYRPVHSELEQRDLSLDLLLPRGMDSFKWASSTDKQPES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUP4-1", "uniprot_id": "CHST5_MOUSE", "id": "Q9QUP4-1", "name": "Carbohydrate sulfotransferase 5", "aln": "------------------------------------------------------MRLPRFSSTVMLSLLMVQT-GILVFLVSRQVPS----------------------------------------------------------------------------------------SPAGLGERVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWDTLSQGSAPALHMAVRDLIRSVFLCDMDVFDAYLPWRRNISDLFQWAVSRALCSPPVCEAFARGNISSEEVCKPLCATRPFGLAQEACSSYSHVVLKEVRFFNLQVLYPLLSDPALN-LRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGTWVEADPRLRVVNEVCRSHVRIAEAALHKPPPFLQDRYRLVRYEDLARDPLTVIRELYAFTGLGLTPQLQTWIHNITHGSGPGARREAFKTTSRDALSVSQAWRHTLPFAKIRRVQELCGGALQLLGYRSVHSELEQRDLSLDLLLPRGMDSFKWASSTEKQPES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VMC4-1", "uniprot_id": "Q9VMC4_DROME", "id": "Q9VMC4-1", "name": "Sulfotransferase domain-containing protein", "aln": "--------------------------------------------------MVSLSRTSKLT--VACVGVYTTYVLFIFFLLPMLMPDPVTLQRSLVS------------------------------------------------------------------YSTSHLGDIRNLTLDAGGQPIRSMLVTFRGSGALTLLDNLAHQPGCYQHYAPLIAYE--SRSIAAK-EHHRALDELAALYNCDYNKSAEMIQWGMRSPVFRRFYG----AQAKICRSYSQEACWDPETMAAVCKLYPFINMAVYN-------------LRLNLLASLLERKDLN-LNIMLLVRDPRGTIYSR----------------MNNKWCSDERDCEA-QELCGDMVSDYQMVETLTQAYPQ-RFSIIRYEDLFLQPDESIKQVFDFYGLPLERNRTRIQKMHPRSGYFFQSSRWKELSSQ----SAFEWISEMMVDDIGAVQDVCGQAMDLWGYRSIQDFNHFSP--ESFQPIMDKAY-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMC3-1", "uniprot_id": "Q9VMC3_DROME", "id": "Q9VMC3-1", "name": "Sulfotransferase domain-containing protein", "aln": "MSTGIGSSSSSTEEQQHLELSADLEACSLLGPQDPSNVDTGRTRAKQRLSLNGKRRRSRMSRRANLIGICGVSSLCILLLIATTQHRPLTTPFNQSAGRDQGASVDGGPSNSLARSAFYDRFQQQLQQQQQSSQTAVYNLTATIVDVLSAQRSRILAEMENFEYPRGGAERLTDMTPETNGTPVRSVVVTSWRSGSTFLGDILNSIPGNFYHYEPLLDFG--IKQIRDPDDQELAVQNLKNLLNCDYADMIDYLNFGKTHTYLFEHNT----RLWDVCREFP-RFCWRPAFLTRFCRLFPIQSMKTVR-------------LRLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQSR----------------RHRVWCGGNEDCEDPRLVCQDLRDDYKTAEVLLLKYPS-RFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHTKVNIGGVSSTYRDSRS-----APFHWMQDLKPEEIKQIQDVCTEAMDLWGYRRIENFNNFSTTQQTFDPMVMPPPFT-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.: . : :.:::. : :: :::: **: : : : *. : * . : . : : : ** : . : . * :. .* .: :.* **. *. :.*: ******..: ** : * : . :* . : . : *: :*:*** .* : : * ** : .: . . * . * : .* :*::* *::* *** : . . : ", "identical_positions": 42, "similar_positions": 81, "identity": "7.79%" }, { "cls_id": "homologset.agr.MGI:1931834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWX4-1", "uniprot_id": "D3ZWX4_RAT", "id": "D3ZWX4-1", "name": "", "aln": "MLEPTHPWGGAFGSRACARVACHGAGRGERGTQGLGFPALQPSSRTQHRRGAERPGLMYRALYAFRSAEPNAMAFAAGETFLVLERSS-THWWLAARARSGETGYVPPAYLHRLQGMEQD-VLQAIDRAIEAVHNTAMRDG-GKYSLEQRGVLQKLIHHRKETLSRRGTSAASASVMTPSTSDHHLDTAVSRQPNGVCRT----GFERQH------------------------------SLPSSEHLGTDGALYQVP-------PQPRRAAPATPPPPVKRRDREALVISGSGGRTAVPSGGSSVSSGSSVSSTSMDTLYTGS-------------------------SPSELGPSCSPTPPPVPRRS-------------AHTTVSQAQPSPSKAPSPEPP---------AEEVAAETNSAPDDLEALD----ALSPETTEE-------------------KPATETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQASVPASSPVMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRAS-----LRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPLDATEQLPDLCMNLLLALNLHLTAPDQNVIMAALSKHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSAATASIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEETSPQCQMDRMIVQEMYKEFPDLGEVPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESJ4-1", "uniprot_id": "SPN90_MOUSE", "id": "Q9ESJ4-1", "name": "NCK-interacting protein with SH3 domain", "aln": "---------------------------------------------------------MYRALYAFRSAEPNAMAFAAGETFLVLERSS-THWWLAARARSGETGYVPPAYLHRLQGMEQD-VLQAIDRAIEAVHNTAMRDG-GKYSLEQRGVLQKLIHHRKETLSRRGTSASSATVMTPSTSDHHLDAAVSRQPNGVCRT----GFERQH------------------------------SLPSSEHLGTDGALYQVP-------PQPRRAAPTTPPPPVKRRDREALVISGSGGRTAIPSGGSSVSSGSSASSTSMDTLYTGS-------------------------SPSELGPSCSPTPPPVPRRG-------------AHTTVSQPQPSPSKAPSPEPP---------TEEVAAETNSTPDDLEAQD----ALSPETTEE-------------------KAAAETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQATVPASSPIMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRAS-----LRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPMDTTEQLPDLCMNLLLALNLHLTAPEQNVIMAALSRHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSSATAAIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEEASPQCQMDRMIVQEMYKEFPDLGEVPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZQ3-1", "uniprot_id": "SPN90_HUMAN", "id": "Q9NZQ3-1", "name": "NCK-interacting protein with SH3 domain", "aln": "---------------------------------------------------------MYRALYAFRSAEPNALAFAAGETFLVLERSS-AHWWLAARARSGETGYVPPAYLRRLQGLEQD-VLQAIDRAIEAVHNTAMRDG-GKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRA----GFERQH------------------------------SLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSS-------------------------SPSEPGSSCSPTPPPVPRRG-------------THTTVSQVQPPPSKASAPEPPA--------EEEVATGTTSASDDLEALG----TLSLGTTEE-------------------KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHILTDADPEVCKKMCKRNEFESVLALVAYYQMEHRAS-----LRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8I5-1", "uniprot_id": "A0AB13A8I5_DANRE", "id": "A0AB13A8I5-1", "name": "", "aln": "---------------------------------------------------------MYHSLFSFSSAEQNALHFPAGEAFLILERSS-AHWWLATRCSSGETGYIPAAYLQKIPAPEQDEVLQSIDRAIEAIHNVAMTNG-GKYNLEQRDVLQKLIHHRKETLSRRSPTPSGVKSKIPSSSSE-ASLSQTPPPNGLSRTPPPNGLSRAHS--------------------------CQGSKPMSERTASVPGLYQVP-------PHPRRAAPDTPPALDKQRNDPPMSLRVSS-TSPTPSSVAPPGPSLSISSASLDSGSSQSGV-----------------------SSDVSLPSVSSTPPPVPKRGKAPPPPPPDQSPQEEPVKKSPAPQPIRSQAPPPPPDLSIKTLTPQPISSQAPPPPTDLSKESPVPQPMGLQPAAEPHPEVEWPLAPPPVSLSPPAGSAQCALPLTIGAELTELVRRNTGLSCELSRVAVGVVVGRLQGALPGAQVQLEQVLQSLA----LSTDLPLGQVCHDQQRLQVIFGDLARHREDSQQRSWALHEDHALIACYLEELLQILTDADAEVCRKMCRVNEFEPVLSLVSYYQMEHRVS-----LRLWLLKVFGAMCGLDAALISTLLNSVLTMELARDLQTDTDEHEKMCYSALLMAMVFSTGEQIPLHHYEHLNAGFLQFLLDVIEDGLPTDSTEQLPDLFINVLLAFNLHLSVPDSNIVMQTLMKRDNAKILSEKLLLLLNRGEDPVCVFSHAPAAPHAVVKFLQDVFSSADSAQIFYRSDLMVLIDITVRQISDLEPGDRMRAQYLSLMLSVMRCSEYQEHRHRLADLRAALQRILGEEESG---AAERSIVLQIYEEFPDTCSS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3K6-1", "uniprot_id": "Q9W3K6_DROME", "id": "Q9W3K6-1", "name": "SH3 domain-containing protein", "aln": "---------------------------------------------------------MLKALYDFQAVYPKTISFDEGEYFILYQTSARQRNWWQVVSMKGNIGFVPSNYVMKIK-VEHDFLISFLNSSIESLEKCTDHEINGIMSKDELLDRLREKKHTMERLYAESSERDGDSSLSYSHSYSDKGSHRHSHPHPTQSQTQLHSQHRQHSPPPSGGSVGSQRLDMSKKSMSSPAVGSSCGLPQNQGMIESPSMGSMQFQGSSCTIQTPQQQQPLPAPPAPAPSPSAASATPTAASTSKAATGGDVAQDNSITSEPSETTTTTTTTSEDVVTTYKETSQMSTSQQHKPQNGSTASASISASASASALRSNGGNGKANGSATALHQELQQEEADSAPDKSDDASAVQSDDGCPANGDSADNSQALDSIDSPSHRQRGLSLGRIEEG-----------------ATGGGQLKVESSDVYQIVDALRRNTNLSFDLSCEALRVVLTSLEQLYNGAINPYLEAVAVHVTGKVATPKELLG-ITHDAKRLQYLFAQLADCKNDTEQRTWMLYEDEEDIIQFLEELVEILINADESISCYEMSCDQYQMFINLVQYYQMETRWS-----IKRLLLKTFTAACHLDYIIVDILLTSVLPLEIVEDMKTHFSNLDRFKQLVKMLTIIFSLGQPMPVNHQDYLGVHFASFLLEIVEG----NNPEVLVDMVIALILAFNQQFSEHTYNVIIEGMQNLPSAKVFTEKLLLLLNREDDPTRLLKHPNEHMNTVLRMFIDIFSHPDTAGMFYTNDIKVLIDIVVRQLSDLDAGSTTRPCYLELCRRILRNTNYQEHQHRKHDLMKIFTRIFCEETECS--ASDQQLVREIANEFPQLFKA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12342-1", "uniprot_id": "LDB17_YEAST", "id": "Q12342-1", "name": "Protein LDB17", "aln": "--------------------------------------------------------------MILDPLSPNIENHTQDEIIEFWEKTE-------------SIANIPKENLDESH--VNSSLVAYLKFATDSYKVFINTDR-DLYRMSLILLESSLFEFKKEFCLSKLQSLLNIDLLEMN------------------------------------------------------------------------------------------MKFIIVYILLCEAKKNVYSLEIMLKFQGFTVFYNTLYTQFAYLSKYGKERTVAS----------------------------------------------------------------------------------------KHQYNSNNSSTGTSLDSLD----------------------------------RSLTDIDLGIIDEMKQISTVLMDLLFQIMKYCK-CVIANLQIVDDFFVYYMMESMRSDTMDDMFNNAEFKLLLALNEQ------YMMFAKEYDIENKVYKYLINGSVSRCFTELLLLKFNRASDPPLQIMMCKIIYLILTPRGDYSPMNFFYTNDLRVLIDVLIRELQNISEDEEVLRNTLLRVLIPLLKNTQLSKTHYRKDDLNKLLNYLSTLDNICVDSPALHEHQVTVALSRKCLQQIPWLETPSTPSDG---------GSSVSSNNTSRNSSIVALGTPDNQNILARKGHLYSNRE------------------------------------------LDVSAESLTKRKAKAPPPPPPPPPSRKCGTPK---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . .* : . : : . . :* : . :. :: :. : :: . : . . .. * . . . . . : * . : . : . .:. . : :: : .* :: . :: :: : : . . : : : : . * ::: : : : * *: : *. : . * *: : : *:: : . : : . *: ::.: ::.. : : :: : . * * . : . : *. : . .. . . * : : . ::::.* * ** :*: .. ::. .. . ", "identical_positions": 22, "similar_positions": 130, "identity": "2.47%" }, { "cls_id": "homologset.agr.MGI:1931835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6QA27-1", "uniprot_id": "TRI44_RAT", "id": "Q6QA27-1", "name": "Tripartite motif-containing protein 44", "aln": "-------------MASGVGAACEELPP-DGTCDECEPDEAPGAEEVCRDCGFCYCRRHADAHRQKFLSHRLAAYVHGAQAWTPPASG-DDALPEDVEAKGEAEGEVESEVGEEESESEVDSESEEESETEEDSEDESDEESEEDSEEEMEDEQESEAEEDNQE-GESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHRGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKVFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEP-KAEGDEEGPSGASEEEDT----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXA7-1", "uniprot_id": "TRI44_MOUSE", "id": "Q9QXA7-1", "name": "Tripartite motif-containing protein 44", "aln": "-------------MASGVGAACEELPP-DGTCDECEPDEAPGAEEVCRDCGFCYCRRHADAHRQKFLSHRLAAYVHGAQAWTPPASGGDDALPEDAEAKGEAEGEVESEVGEEESETEVDSESEEESETEEDSEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHRGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKIFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEP-KAEGDEEGPSGASEEEDT----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DX7-1", "uniprot_id": "TRI44_HUMAN", "id": "Q96DX7-1", "name": "Tripartite motif-containing protein 44", "aln": "-------------MASGVGAAFEELPH-DGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADG-EGAGKEEAEVKVEQEREIESEAGEE-SESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEP-KAEGDEEGPSGASEEEDT----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IW76-1", "uniprot_id": "A0AC58IW76_DANRE", "id": "A0AC58IW76-1", "name": "", "aln": "MMCVVMLCSESPSCSMDVCMLEEDLPQMDGTCDACEPDEAESALWMCVRCRFAFCSSHADAHTQS-TAHTLQPYSS----------------------------------------------------------------------------------------AEADTHSAEPQAAALPPDGRRETVSVERLKCRDHGQEGALYCKHDQRIICVLCAVQGEHRGHQIITLREAYLWQKSKEGIDLLEQTHEISERIKAKWASPDMSMEELEAYVNQQFDELQRLVRLEEWRVLHLVDLKEAFLTAQAAEKISEISAHTQTLQEEMDSITHTLQQMEQVEEDGGAPAALLAPLLARREEDAGGRAVRNTYKHTHTHSTKTGHTPAGYERVLQVEKREQQMISVDTDMISVNVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* *:** ***** ****** .* :* * *.:* **:** *. :* * * .*:::.. : : *: . *: * : ** *** : : **:.*:::*****.* * *:***: ** **: :**:. .* *: **:* * :.*.:: :::: :::*:*.::*::: ** :.*****::**: **:.:* :::*.:* : * :* . .. *: :: * * . .* * .***: ", "identical_positions": 91, "similar_positions": 83, "identity": "22.03%" }, { "cls_id": "homologset.agr.MGI:1931838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07266-1", "uniprot_id": "DREB_RAT", "id": "Q07266-1", "name": "Drebrin", "aln": "MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQG-----VDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQSLEAEEAKRRLKDQSIFGDQRDEEEESQMKKSESEVEEAAAIIAQRPDNPREFFRQQERVASASGGSCDAPS--PFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPTRSPSDSSTASTPITEQIERALDEVTSSQPPPPPPPPPPAQEAQESAPRLDGEEVCKEAKVAAAPQVWAGCAEEPPRAQEPPLLQSSPTEDLMCTESPEQAVLAASPEPDASVTSVADAHAADTIETTTATTATTIADNVTPAAASLIDLWPGNGEEASTPQAEPRVPTPPSGAEASLAEVPLLNEAAQEPLPPVGEGCANLLNFDELPEPPATFCDPEEEAEGEPLAASQVLTMP--SALEEVDQVLEQELEPEPHLLTNGETTQKEGTQQASEGYFSQSQEEEFAQSEEPCAKAPP-PVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXS6-1", "uniprot_id": "DREB_MOUSE", "id": "Q9QXS6-1", "name": "Drebrin", "aln": "MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQG-----VDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQSLEAEEAKRRLKEQSIFGDQRDEEEESQMKKSESEVEEAAAIIAQRPDNPREFFRQQERVASASGGSCDAPAPAPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPTRSPSDSSTASTPIAEQIERALDEVTSSQPPPPPPPPPPTQEAQETTPSLD-EELSKEAKVTAAPEVWAGCAAEPPQAQEPPLLQSSPLEDSMCTESPEQAALAAPAEPAASVTSVADVHAADTIETTTATTDTTIANNVTPAAASLIDLWPGNGEEASTLQAEPRVPTPPSGAEASLAEVPLLNEAAQEPLPPVGEGCANLLNFDELPEPPATFCDPEEEV-GETLAASQVLTMP--SALEEVDQVLEQELEPEPHLLTNGETTQKEGT-QASEGYFSQSQEEEFAQSEEPCAKVPP-PVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16643-1", "uniprot_id": "DREB_HUMAN", "id": "Q16643-1", "name": "Drebrin", "aln": "MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQG-----VDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPS--PFNHRPG----------------------------------------------SHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILD-----SEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEP-ATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEPPATFCDP-EEVEGESLAAPQTPTLP--SALEELE----QEQEPEPHLLTNGETTQKEGT-QASEGYFSQSQEEEFAQSEELCAKAPP-PVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ALR8-1", "uniprot_id": "A0A8M3ALR8_DANRE", "id": "A0A8M3ALR8-1", "name": "Drebrin", "aln": "-MAVNLSKNRLALLTAYQDVINETSANDWALYTYEDDSNDLILSASGDGGLAEIAVTFDNTRIMYGFCSLKDATSALPRYILINWVGEDVPDARKCACASHVATIAEFFQVGLPKGVDVIVNASSLEDIDPSAIGQRLTNGTVPVASPVLSRLKMKDEENGEHVGTTYQKTNAEIEMKKINREEFWEQAKREEETRKEEERRKAAEERQRFENERMELERKEQEEREKRYREREQQIEEHRKK--ILEEEEAKERTRNQPLITEPSCED--PSLEKKESEVEEAAAIIAQRPSNPREFFKQRERAIAN---SVDISP--VMTHRTG-----------------------------------------------RLDS-----PFLRQQHSPSDCSPS---------------PSRTPPLSRRQPGPPDDFDEG--ILE-----RSMTTGCTPIPRIAIQEEKDDFFRKEFGFDSPKQTPVQESGFTKASPSISPQP------------------------SSVAP-LPSTDESLLDLWDSG-------------PAPAIALSQASTHIMDLMEDTPEPHPAGSSPAQPLLSFDEVPDAPYCPGTEDDPSSLVDVAGPHQMTLSYQQALQHASGSDSQDMDDGQLLLTNGDTLLKEGT-QASEGYFSQSQEEDFVQSDDCTAKVNPTPVFYNKPPEIDITCWDTDPVMEDDD------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*.:* :** **:**::**.* ** *********.*:** *:***:*** *:: *:* ::******:**: :***:*:**********************.:***** *********:****..******:** . ::**** **:::::**.* ********:* :***:****:******:*** ******:** : * ***:**** **:******:*************:* ** ****.* ::*.:: : *: . ::*.***************.******:*:**. : * * .. :.**.* :*** * :****.*.: .* ** * *.:: :* *: . . .:* . * .** : : .. :* : . :* :::* :..: **:*** .. *:*. . . : :.: * * : ** . .. . **.***:*:.* : :*..: *:. .**:. . *: : *****:* **** *************:*.**:: **. * ****************:*** *::: ", "identical_positions": 301, "similar_positions": 145, "identity": "41.98%" }, { "cls_id": "homologset.agr.MGI:1931870", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MGC7-1", "uniprot_id": "Q6MGC7_RAT", "id": "Q6MGC7-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSPMSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSSAATTTVTAVAAPSVSVPCASVPSGSGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSSSQDAFVASAVGSGNRRDGGPVFPVPVVGSAGTTSGKLLLEADELCDDGGDGRG------AAAPGAGLRRPNCLPASAVPQKHWVYVKRARNCPAPASLVHQDPDLEDEEE--EEDLVLTCEDDEDEDLGNGSGVPAGGEPEATLSISDVRTLTEPAEKGEE--QVNFCESSNDFGPYEGGGAGAGLDDPGGPTPS------------SYGLTHPPRPLLPLDVPGNQILVFPSSSS----------QAPGQPPGNTAEHGAVTLGGASAVGLGIPSGSGGTPGGAGNSDGNKIFLCHCGKAFSHKSMRDRHVNM-HLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGAGGAASVPGPGPG--APTGP-----------ALQPKRESSAVGGGSGDEANSATPPSNRRVWSPPSVHKVEMDFSGGGGAAH-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0G7-1", "uniprot_id": "ZBT22_MOUSE", "id": "Q9Z0G7-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSALSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSAATTTTVTTAAAPSVSVPCASVPSGNGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSTSQDAFVASAAGSGNRRDGGPVFPAPVVGSAGTTSGKLLLEADELCDDGGDGRG------AVAPGAGLRRSNCMPASAVPQKHWVYVKQARNCPAPASLVHQDPDLEDEEE--EEDLVLTCEDDEDEEMGGGSGVPAGGEPEATLSISDVRTLTEPADKGEE--QVNFCESSNDFGPYEGGGAGAGLDDPGGPTPS------------SYALTHPPRPLLPLDVPGNQILVFPSSSS----------QAPGQPPGNTAEHGAVTLGGTSAVGLGIPSGSGGAPGGTGNSDGNKIFLCHCGKAFSHKSMRDRHVNM-HLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGVGGVGSGPGPGPGPGTPSGP-----------ALQPKRESSTVGGGSGDEANSATPPSHRRVWSPPSVHKVEMDFSGGGGAAH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15209-1", "uniprot_id": "ZBT22_HUMAN", "id": "O15209-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGR-ASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRG------AVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQDPDLEEEEE--EEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPDKGEE--QVNFCESSNDFGPYEGGGPVAGLDDSGGPTPS------------SYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSS------QAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNM-HLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLG--GVGAVPGPG----TPTGP-----------SLPSKRESPGVGGGSGDEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUU5-1", "uniprot_id": "Q1LUU5_DANRE", "id": "Q1LUU5-1", "name": "", "aln": "--------------MQSATADQTFVDSTGSVVQVCFPRAQTSVLDSLNRQREEGHLCDLSIHVQGQVFKAHRCVLAASSPYFHDQVLLKNMSTVSIPAVMDPLAFESVLSCAYTGQLRMLREDIVNYLTVGSVLQMWHIVDKCTELLKEGKGGSSGPQGSGEKENIGQGSGTNKVAQADGGEAPSTP---QPPSRPSFSESQSPSSTNYFSPRD-ANFGG---AMVSTIAVGEGAVHS-TPSYCMPSGGEEGFMIEDEEDDDDELLFSRKRDRGGKQKSTSSVSDQEVGVSDSFGVSSYQDGDSSPPQKHPSYIQPSIMPRKQWVVVKTEHSRDDDLIVVSGGEEGGDDEEEREMAIVRERDRTFNISNVRTLSGLREDAEMDAQVDYCQSSEDYLKFERGIIDQTSSQHPPENSSQCPNRAMSGMLGSVQSTSARAQLFPLDMQGNQILLYNQAALESTSPLGLTGGMSGVSLKGSLEHGAVHLPSQGALGSGMEGLDAGSAGSSG-----KVFMCHCGKTFTHKSMRDRHINM-HLNLRPFHCPVCAKKFKMKHHLTEHMKTHTGLKPYDCHGCGKKFMWRDSFMRHRSHCERRGRSERASERSVISPPHHLKLPSASEPNQGGAGARSGLPILSPQHSISSNGVSCLSMAASGSLLGMSSQSGSHSLGSGILGIGGNRSGCVEDVCEENVDESSVT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QFB7-1", "uniprot_id": "F1QFB7_DANRE", "id": "F1QFB7-1", "name": "", "aln": "--------------MEQMFGRS--SAPPGPVLQVCFPSARASVLENLNRQREEGQLCDLSIQVQGQVFRAHRCVLAASSPYFHDQVLLKNVTTVSLPSVMDPLAFESVLNSAYTGQLSIVRDDIINYVTVASFLQMWHIVDKCTDILKRSRPLAQISPGGATSSSHQSPSSSDCCFADPEDATTEQTLEKRPHSALPPLATWRRPQQNRWS-RSTLTFPLRPDSECGSNAAG----VHGCSAAPLPS------LVSPPELDFAARHRIRVRLRG------AKEEEEQRRMEADEGVGEPSQEDRVRVK-------------------NEEH-------QAGVAEPDGSLRESESRESLQETDGLWQSVTEWPLDDKVLDEDD--KTDLSFETYDEIEKATGQISQ-------------------------------RPLLPSELS------------------------------------WVSQSSSSSPCSPLSATP-------------KVHFCHCGKAYTLKSMRDRHVKMQHLNLRPFSCPVCSKSFKMKHHLTKHVKTHGGLRPYECSVCGKKIVWRDSFLKHQARCQR----------------------------------------TPETSAESGGQQEDADGAG-----QVKVEQDDYSLQEEEMHS----------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ....*::*.** . :::*:.**:** :*:***:**:***: *:***.****************.::::*:*:**** ***:** .****:* : **:*::**.*.***********::*:..: : . . :. :. :. : . .. * :* *. * : *.* . * : ** : . : . : . *. . : . . : . .* . : :.: . .: * * *:* :: * . . : . *:.:*****::: *******::* ******* **** *.********:*:*** **:**:* *.**::*****::*:.:*:* ... . . * : :.: ", "identical_positions": 143, "similar_positions": 124, "identity": "20.46%" }, { "cls_id": "homologset.agr.MGI:1931871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XQ12-1", "uniprot_id": "A0A8J8XQ12_RAT", "id": "A0A8J8XQ12-1", "name": "WD repeat-containing protein 46", "aln": "MKSRGLPEVSSQALGRLKGVLHVDRRSVVGMETAPKPGRGDPPKKDKPQAKRKKPRRYWEEEPTPSAAGASPGPPRKKARTGEPRPPRSQSARIAQKPRFSKKPPIPKNASDWKKP--QRTLSGAQDPFPGPVPAPLEVARKFCRIDKSKKLPHSKPKTQSQLEKAEAQEEEASVRAARAELLLAEEPGFLVGE-DGEDTAKILQTDIVEAVDISSAAKHFDLNLRQFGPYRLNYSRTGRHLALGGRRGHVAALDWVTKKLMCEINVTEAVRDIHFLHSEALLAVAQNRWLYIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIVTALNARAGRLNVMAQNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVGVDSTGTYMATSGLDHQLKIFDLRG--TFQPLSSRTLPQGAGHLAFSQRGLLVAGMGDVVNIWAG--QGKGSP----------PSLEQPYLTHRLSG-NVHGLQFCPFEDVLGVGHSGGITSMLVPGAAEPNFDGLESNPYRSRKQRQEWEVKALLEKVPAELICLDPRALAEVD---------VTTLEQQKKERIERLGYDPDAKAAFQPKAKQKGRSSTASLVKRKKKVMDQEHRDKVRQSLEQQQ-KKKQDKAKP-GAHPSALDRFVR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H1-1", "uniprot_id": "WDR46_MOUSE", "id": "Q9Z0H1-1", "name": "WD repeat-containing protein 46", "aln": "------------------------------METAPKPGRGVPPKRDKPQAKRKKPRRYWEEETTPAAVATSPGPPRKKARTGESRPPRSKSAHIAQKSRFSKKPPISKTAPDWKKP--QRTLSGAQDPFPGPVPAPLEEARKFCRIDKSKTLPHSKPKTQSKLEKAEAQEEEASVRAARAELLLAEEPGFLVGE-DGEDTAKILQTDIVEAVDIASAAKHFDLNLRQFGPYRLNYSRTGRHLALGGRRGHVAALDWVTKKLMCEINVMEAVRDIHFLHSEALLAVAQNRWLYIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATTSETGFLTYLDVSVGKIVTALNVRAGRLSVMAQNPYNAVIHLGHSNGTVSLWSPAVKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRG--TFQPLSSRTLPQGAGHLAFSQRGLLVAGMGDVVNIWAG--QGKASP----------PSLEQPYLTHRLSG-HVHGLQFCPFEDVLGVGHSGGFTSMLVPGAAEPNFDGLENNPYRSRKQRQEWEVKALLEKVPAELICLNPRALAEVD---------VVTLEQQKKERIERLGYDPDAKAAFQPKAKQKGRSSTASLVKRKKKVMDQEHRDKVRQSLEQQQQKKKQDMAMPPGARPSALDRFVRRAREGGLQVDP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15213-1", "uniprot_id": "WDR46_HUMAN", "id": "O15213-1", "name": "WD repeat-containing protein 46", "aln": "------------------------------METAPKPGKDVPPKKDKLQTKRKKPRRYWEEETVPTTAGASPGPPRNKKNR-ELRPQRPKNAYILKKSRISKKPQVPKKPREWKNPESQRGLSGTQDPFPGPAPVPVEVVQKFCRIDKSRKLPHSKAKTRSRLEVAEAEEEETSIKAARSELLLAEEPGFLEGE-DGEDTAKICQADIVEAVDIASAAKHFDLNLRQFGPYRLNYSRTGRHLAFGGRRGHVAALDWVTKKLMCEINVMEAVRDIRFLHSEALLAVAQNRWLHIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIVAALNARAGRLDVMSQNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRG--TYQPLSTRTLPHGAGHLAFSQRGLLVAGMGDVVNIWAG--QGKASP----------PSLEQPYLTHRLSG-PVHGLQFCPFEDVLGVGHTGGITSMLVPGAGEPNFDGLESNPYRSRKQRQEWEVKALLEKVPAELICLDPRALAEVD---------VISLEQGKKEQIERLGYDPQAKAPFQPKPKQKGRSSTASLVKRKRKVMDEEHRDKVRQSLQQQH--HKEAKAKPTGARPSALDRFVR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3K3-1", "uniprot_id": "Q9W3K3_DROME", "id": "Q9W3K3-1", "name": "BING4 C-terminal domain-containing protein", "aln": "------------------------------MTKVTPKGR---PKAKTP------YKRYFDGQ-----KDTETGDGDLKHVKVFSKNRQNFTGDFISMINKTKKPRPQKAP---AKP-----TKEELEARPKKNPIPKEILDKYSRGEQVQPKGVKTRHFKEQQTRKEVYLEYATEQAARTELLLQETAGQLQAD-EGETTAEFRQSQIAENVDIQSSAKHFNLNM-EFGPYRMRYTKNGRHLLLGGKRGHVAAFDWVTKRLHCEFNAMESVEDVQWLHVPTMYAVAQKSWVYFYDKKGTELHCIKRLNRVNRLDFLPYHFLLAAGNSAGYASWLDVSIGELVGNFNTGLGDIRMLRHNPRNGVLCIGGGRGVVSMWSPKVREPLAKLLCHSTAMSALAVEPKGQYLVTAGLDRAVKVWDIRMLVHDKPLTHFQLRLPANELDVSQRGMLALSQGTYLETYSDLLSGGGSG----------DGTRLPYIRQRCDA-FVHGLRFCPYEDVLGVSTAKGFQSLLVPGSGEPNFDAMEDNPYETSKQRREHEVHALLEKIPPELITLDPQEITGVD---------APTL-QEKIDAKRKLFHLKAPRINMKSRHKMKGRGGTAKAARNKQIVKDAKRKEFIAEVREAKKNVIKQHTADEVGAKGKAKTKAPRSVLDRFKPKPPKKQKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40055-1", "uniprot_id": "UTP7_YEAST", "id": "P40055-1", "name": "U3 small nucleolar RNA-associated protein 7", "aln": "----------------------------------------------------------------------------------MGHKKNGHRRQIKERENQNKFER-----------------------------------STYTNNAKNNHTQTKDKKLRAGLKKIDEQYKKAVSSAAATDYLLPESNGYLEPENELEKTFKVQQSEIKSSVDVSTANKALDLSLKEFGPYHIKYAKNGTHLLITGRKGHVASMDWRKGQLRAELFLNETCHSATYLQNEQYFAVAQKKYTFIYDHEGTELHRLKQHIEARHLDFLPYHYLLVTAGETGWLKYHDVSTGQLVSELRTKAGPTMAMAQNPWNAVMHLGHSNGTVSLWSPSMPEPLVKLLSARGPVNSIAIDRSGYYMATTGADRSMKIWDIRN--FKQLHSVESLPTPGTNVSISDTGLLALSRGPHVTLWKDALKLSGDSKPCFGSMGGNPHRNTPYMSHLFAGNKVENLGFVPFEDLLGVGHQTGITNLIVPGAGEANYDALELNPFETKKQRQEQEVRTLLNKLPADTITLDPNSIGSVDKRSSTIRLNAKDLAQTTMDANNKAKTN-SDIPDVKPDVKGKNSGLRSFLRKKTQNVIDE-RKLRVQKQLDKEKNIRKRNHQIKQGLISEDHKDVIEEALSRFG---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . .* .: . : . . : : : : : ** :: ** * * * : : * * :. *::* . **: :: * ::*.: :****::.*::.* ** : *::****::** . :* .*: *: .. :*: ****: : .:**::* *** ::: .. :*:***:*:**.: ..:*: .: *** *::* :.. * : :** *.*: :* ..*.**:*** : ***.*:*. : ::.:: .* *:.*:* *: :*::*:* : : * . .: .*: *:*. . * : : . . .. . **: : . *..* * *:**:***. *: .::***:.*.*:*.:* **:.: ***:* **::**:*:*.: * *:*. : ** . * * . : .: .:. * *. . : :..: * * :: : : : :: *. * . . ", "identical_positions": 132, "similar_positions": 183, "identity": "19.3%" }, { "cls_id": "homologset.agr.MGI:1931874", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYJ3-1", "uniprot_id": "DNJB1_MOUSE", "id": "Q9QYJ3-1", "name": "DnaJ homolog subfamily B member 1", "aln": "----------MG----------------KDYYQTLG----LARGASDD-EIKRAYR--------------------------------------------RQALRYHPD-------------------KNKEPGAEEKFKEIAEAYDVLSD-------------PRKREIFDRY------------GEEGLKGGSPSGGSSGGANGTSFSYTFHG-DPHAMFAEFFGGRNPFDTFFGQRNG-EEG----MDIDDTFSSFPMG-MGGFTN---------MNFGRSRPSQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKITFPKEGDQTSNN-IPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPV-VFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSRTILEQVLPI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25685-1", "uniprot_id": "DNJB1_HUMAN", "id": "P25685-1", "name": "DnaJ homolog subfamily B member 1", "aln": "----------MG----------------KDYYQTLG----LARGASDE-EIKRAYR--------------------------------------------RQALRYHPD-------------------KNKEPGAEEKFKEIAEAYDVLSD-------------PRKREIFDRY------------GEEGLKGSGPSGGSGGGANGTSFSYTFHG-DPHAMFAEFFGGRNPFDTFFGQRNG-EEG----MDIDDPFSGFPMG-MGGFTN---------VNFGRSRSAQEPARKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKKGWKEGTKITFPKEGDQTSNN-IPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPV-VFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLIIEFEVIFPERIPQTSRTVLEQVLPI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZUU5-1", "uniprot_id": "D3ZUU5_RAT", "id": "D3ZUU5-1", "name": "", "aln": "MSCVTQRAAAIGRCGATHREGRKVLEGWRDLEASAGRVYRVRDGAAAEPEAATAGRRWPWARTTTRRWAWPAARPTTRSSGPTAARRCATTRTRTRSPAPRRSSRRSPRPTTCSATRASARFSTAMERKVRVRAARVTRRLTGEETEALGASLRLRRGTDGPGIPRRRCLLHLLSNRRPQTGG---GALGLKGGGPSGGSSGGANGTSFSYTFHG-DPHAMFAEFFGGRNPFDTFFGQRNG-EEG----MDIDDPFSSFPMG-MGGFTN---------MNFGRSRPTQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKITFPKEGDQTSNN-IPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPV-VFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPDRIPISSRTILEQVLPI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PA47-1", "uniprot_id": "A0A8M1PA47_DANRE", "id": "A0A8M1PA47-1", "name": "", "aln": "-------MVKMG----------------KDYYSVLG----IQKGASDD-EIKKAYR--------------------------------------------KQALKYHPD-------------------KNKSAGAEEKFKEIAEAYDVLSD-------------PKKKDIYDRF------------GEEGLKGGAPGGGGGGGN----YTYTFQG-DPHAMFSEFFGGRNPFEHIFGHNGGMDEN----METDDPFASFGMGGIGGFPR---------SFTTHSHGGR--MERKQDPAVIHDLRVSLDEVFTGCTKKMKISRKRLNPDGRTTRSEDKILTVEVKKGWKEGTKITFPREGDETPSN-IPADVVFVLKDKPHPVYKRDGSDIIYPAKITLKEALCGCVINVPTLDGRTVKV-TSQDIVRPGMKRRLTGEGLPLPKAPDRRGDLVVEYEVRFPEKLSQNAKDTIANVLPAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPY9-1", "uniprot_id": "Q9VPY9_DROME", "id": "Q9VPY9-1", "name": "J domain-containing protein", "aln": "----------MG----------------KDYYKILG----LPKTATDD-EIKKAYR--------------------------------------------KLALRYHPD-------------------KNKAANAEDKFKEVAEAYEVLSD-------------KSKREVYDKY------------GEDGLKSGGTR---NGGPSSNSFTYQFHG-DPRATFAQFFGNSNPFASFFDMGDNLFDKKVFDLDTEPDFFSSPFGGIGSRHGLGSGFRPSFRSHSFNVHTPFKKEQKQDPPVEHDLYVTLEEIYHGCVKKMKISRRIVQADGSS-RKEEKFLAISIKPGWKSGTKVTFQKEGDQAPGK-IPADIVFIIRDKPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRISTMQEIIKPNTVKRIQGYGLPFPKDTTRKGDLLVAFDIQFPEKLTAAQKEVLKDML---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24133-1", "uniprot_id": "DNAJ1_DROME", "id": "Q24133-1", "name": "DnaJ protein homolog 1", "aln": "----------MG----------------KDFYKILG----LERKASDD-EIKKAYR--------------------------------------------KLALKYHPD-------------------KNKSPQAEERFKEIAEAYEVLSD-------------KKKRDIFDNY------------GEDGLKGGQPGP--DGGGQPGAYTYQFHG-DPRATFAQFFGSSDPFGAFFTGGDNMFS------GGQGGNTNEIFWNIGGDD-----------MFAFNAQAPSRKRQ-QDPPIEHDLFVSLEEVDKGCIKKMKISRMATGSNGP--YKEEKVLRITVKPGWKAGTKITFPQEGDSAPNK-TPADIVFIIRDKPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLPVPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSELLPN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25294-1", "uniprot_id": "SIS1_YEAST", "id": "P25294-1", "name": "Protein SIS1", "aln": "------------------------MVKETKLYDLLG----VSPSANEQ-ELKKGYR--------------------------------------------KAALKYHPD---------------------KPTGDTEKFKEISEAFEILND-------------PQKREIYDQYGLEAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSGFSFSSYP----SGGGAGMGGMPGGMGGMHGGMG------GMPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGRK-----GPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQPVQ-PSQTSTYPGQGMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDENF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : * : * . * : : : * : : .* : *. :: : . * * .. ** : * . *. *::***. .** . . . :*. :: .: :* *:*::: * *.:**.: * .*.. : : :* *** ***:*: .:** . . : *::::*.* :**:* *: *. ::::::* * : *:.* : : : : * * *:* ** . ::*:*:: :.: :* : : : : : ", "identical_positions": 60, "similar_positions": 94, "identity": "12.55%" }, { "cls_id": "homologset.agr.MGI:1931881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYI4-1", "uniprot_id": "DJB12_MOUSE", "id": "Q9QYI4-1", "name": "DnaJ homolog subfamily B member 12", "aln": "MESNKDEAERCISIALKAIQSNQPERALRFLEKAQRLYPTPRVSALIESLNQKPQSTGDHPQPTDTTHTTTKKAGGTETPSANGEAGGGESAKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHG------HSHGDFH-------RGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCNRLSEVQASLHG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F4L4-1", "uniprot_id": "F7F4L4_RAT", "id": "F7F4L4-1", "name": "", "aln": "MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVTALIESLNQKSQSAGDQSQPTDTTHTTTRKTSGTETPSANGEAGGGESTKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKNQAARHG------HSHGDFH-------RGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMSTPSCSRLSEVQASLHG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NXW2-1", "uniprot_id": "DJB12_HUMAN", "id": "Q9NXW2-1", "name": "DnaJ homolog subfamily B member 12", "aln": "MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVRALIESLNQKPQTAGDQPPPTDTTHATHRKAGGTDAPSANGEAGG-ESTKGYTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHG------HGHGDFH-------RGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHRRVTDHLGVVYYVGDTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCSRLSEVQASLHG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFP0-1", "uniprot_id": "Q9VFP0_DROME", "id": "Q9VFP0-1", "name": "J domain-containing protein", "aln": "MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLLAQLKSTP--SNESNGKSRTAGASDEKDSG---PRKRVNSDSRSSAPDYTKDQLEAVRKVKTCKDYYEVLGVSKTATDSEIKKAYKKLALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYGINESHNG-HGNNGGGHHGHGQYYNNEYGYSRGFQADISAEELFNMFFNGGFPQQNVHMR---QQRRRQQAREDREGNNSS----ALVNLLPIVLLIGLSMMSSFFISDPMYSLTP--SHKYSVKRETNSLKVPYYVKDNFYSEYQG-SVARLEESVEEDFVNHLKHSCSRERNYRDSMLAKARTFGDRDLYRKAQNINTPSCENLQKYLIT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48353-1", "uniprot_id": "HLJ1_YEAST", "id": "P48353-1", "name": "Protein HLJ1", "aln": "------------------------------------------------------------------------------------------MSFTEDQEKIALEILSKDKHEFYEILKVDRKATDSEIKKAYRKLAIKLHPDKNSHPKAGEAFKVINRAFEVLSNEEKRSIYDRIGRDPDDRQMPS--------RGAAS--------GFRGSAGGS-----PMGGGFEDMFFNSRFGGQRAGPPEDIFDFLFNAGG---------SPFGASPFGPSASTFSFGGP-----------GGFRVYTNNRGGSPFMRQ------QPRSRQQQQQAEENAVNSQLKNMLVLFIIFIVLPMIKDYLFS----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: * :::**:* *.: *:*.::****::**:::***** * * ****.:. * **:: ***. ** * : .. . :* **... . . :.*** . .: : : * * .. *: . * : ...* : *: :: : * :. *: :*:: : : *. ", "identical_positions": 49, "similar_positions": 64, "identity": "12.6%" }, { "cls_id": "homologset.agr.MGI:1931882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYJ0-1", "uniprot_id": "DNJA2_MOUSE", "id": "Q9QYJ0-1", "name": "DnaJ homolog subfamily A member 2", "aln": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPN--AGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGM--------DDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNG-KTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHM-TYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSR--PEVPNVIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEESSS------HHGPGVQCAHQ----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60884-1", "uniprot_id": "DNJA2_HUMAN", "id": "O60884-1", "name": "DnaJ homolog subfamily A member 2", "aln": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPN--AGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGM--------DDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNG-KTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHM-TYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSR--PEVPNIIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEESSS------HHGPGVQCAHQ----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35824-1", "uniprot_id": "DNJA2_RAT", "id": "O35824-1", "name": "DnaJ homolog subfamily A member 2", "aln": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPN--AGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGM--------DDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNG-KTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLFVQEKEHEVFQRDGNDLHM-TYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSR--PEVPNVIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEESSS------HHGPGVQCAHQ----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25491-1", "uniprot_id": "MAS5_YEAST", "id": "P25491-1", "name": "Mitochondrial protein import protein MAS5", "aln": "--MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKNPSEEAAEKFKEASAAYEILSDPEKRDIYDQFGEDGLS-GAGGAGGFPGGGFGFGDDIFSQFFG------AGGAQRPR-GPQRGKDIKHEISASLEELYKG-RTAKLALNKQILCKECEGRGGKKGAVKKCTSCNGQGIKFVTRQMGP-MIQRFQTECDVCHGTGDIIDPKDRCKSCNGKKVENERKILEVHVEPGMKDGQRIVFKGEADQAPDVIPGDVVFIVSERPHKSFKRDGDDLVY-EAEIDLLTAIAGGEFALEHVSGDWLKVGIVPGEVIAPGMRKVIEGKGMPIPKYGG-YGNLIIKFTIKFPENHFTSEENLKKLEEILPPRIVPAIP-KKATVDECVLADFDPAKYNRTRASRGGANYDSDEEE--------QGGEGVQCASQ----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PD23-1", "uniprot_id": "M9PD23_DROME", "id": "M9PD23-1", "name": "", "aln": "---MDNLNLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPD--AGDKFKEISFAYEVLSDPEKRRIYDRYGLKGLQEGAEGFSDA--------SEFFAQWFP------FDRVSSEGRGRRNGK-VVVKVELTLEEIYVGGMKKKVEYNRQKLCSKCNGDGGPKEAHESCETCGGAGRAAAFTFMGL---SPFDTTCPTCDGRGFTIRDDKKCSPCQGSGFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQMEHPIFQRRHANLYMRDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFNKATDSGDLYMKFKVKFPDNDFATAPQLAMLEDLLPPRQPIVIP---KNAEEVQMTDYKPQPRQQEDEDGQSSHFEGVQCQTAXCMWLWLLQARYLCLDLWLILGTFSVDEVCFLVPLFVLICIVLFFIQECLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::**:* *. *:: *:** *** * ::******. *.:**** * ***:**:**** :**::* .** *: * .. .::*:: * . . * :.*: : :. :**::* * . *: .:: **. *.* ** . * :.* :* * * :. . ::: * *.* * * ..:*. *:*. . :: :: *: * . :: * .*..* . **::..:.: * *:* :* :*.: *:.* .. ::*:.. : : **:*: . :::.*.*** . *:* :** ::**:*.: . :* **::**.* :* .:* : ::.. . . : .. : . * ", "identical_positions": 106, "similar_positions": 135, "identity": "22.75%" }, { "cls_id": "homologset.agr.MGI:1932027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWJ6-1", "uniprot_id": "A0A0G2JWJ6_RAT", "id": "A0A0G2JWJ6-1", "name": "", "aln": "KMKGSPTIPPAGCLLPLLLLVFAGVSGEASWFSVKGPAEPITVLLGTDATLPCQLSPKQSAAHMHIRWYRAQLTPAVLVFHNGQVQGEVQMPEYEGRTQMLG-----HDIDTGSVALQIQQVQASDDGLYHCQFSDGFTSQEVSIELQVVGLGSAPLVHMTGPENNGIRVLCSSSGWFPKPRVQWRDTIGDTLLSSSESQTLDRDGLFHIETSLLVTDRAIGNVICSIQNPIWDQEKSKAILLPEPFFPTTSPWKVALACILPILLVILAWTSFATWKEHQVKRREEKQLSKEQWEMRQMKEETKSAVKDRDDLQTDLDRRKALYKEDWKMALLYPDWRKELFQLAPVMIDHEMPDQNKSDPKTEENRGEGTADPSVDNSQVDDNIITLSQEGFMLGRYYWEVDVEDT-----EEWTLGVY---ELYTEDASPTE-SKKFRVLEKKGDGYRALAFCSQNISLEEPLQLETRPLKIAIFLDQEDNDLSFYNMTDETHIFSFDQNTFLGSLYPYFKR------------------NSMALSPTEQP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TST0-1", "uniprot_id": "BTNL1_MOUSE", "id": "Q7TST0-1", "name": "Butyrophilin-like protein 1", "aln": "MMKGSPSVPPAGCLLPLLLLLFTGVSGEVSWFSVKGPAEPITVLLGTEATLPCQLSPEQSAARMHIRWYRAQPTPAVLVFHNGQEQGEVQMPEYRGRTQMVR-----QAIDMGSVALQIQQVQASDDGLYHCQFTDGFTSQEVSMELRVIGLGSAPLVHMTGPENDGIRVLCSSSGWFPKPKVQWRDTSGNMLLSSSELQTQDREGLFQVEVSLLVTDRAIGNVICSIQNPMYDQEKSKAILLPEPFFPKTCPWKVALVCSVLILLVLLGGISLGIWKEHQVKRREIKKWSKEHEEMLLLKKGTKSVLKIRDDLQADLDRRKALYKEDWKKALLYPDWRKELFQEAPVRINYEMPDQDKTDSRTEENRGE----ETVSSSQVDHNLITLSQEGFMLGRYYWEVDVKDT-----EEWTLGVY---ELCTQDASLTDPLRKFRVLEKNGDGYRALDFCSQNINSEEPLQLKTRPLKIAIFLDQEDNDLSFYNMTDETHIFSFAQVPFLGSPYPYFTR------------------NSMGLSATAQP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A9L4-1", "uniprot_id": "A0AB13A9L4_DANRE", "id": "A0AB13A9L4-1", "name": "", "aln": "-------MRSIIVLLLLNLLTDCSVS-----FTAKVPPGPVVAHVGSTVILPCWISPAQNAEALEIRWYRHEDFRYTVLYFQHGKIQDEQEETFRNRSSLTPRSDLSGGLKGGDVSLQLEKIIIQDEALFHCYVNGDSDYSSAELELKVTAPGSAPVLFPRPLDDGRLNVSCSSSGWYPEPNITWTSDQRKTLRPAAVSLHRAADGLFSVHSWTTVSPSDAQLVSCSVSTTTGESKEGKVDIQGFISSDSSDLWKPLFLTLLICALLGLAGLILYKYRNILTGKKAAG------------PDGENLPVQERKGYIEVQMSDNAYENASVPVDMNIEDLRKHAEQITIDRENISPDLTVSGDCKSVRDSPK----YHHTAEEFPYQLCAFGAQQFTSGRHYWELELALPPNPPKLSWLIGVVKHKHFSGKDRSALTPSRGFWFLCSDGENG-----FNTNTDPPITLSISPRPERLGVLLDYDEGLLEFYNVKERKHLLSMHTR-FSGSIVPLFNPGVGDKSPLKIVDCPVEEDSPAELTVPSQSNCSAENITEA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ** * ** .** *:.* *. *:.. :*: . *** :** *.* :.***** : .:::.: : * :..*:.: :. *.*:**:::: .*:.*:** .... ....:**:* . ****::. ::. :.* ******:*:*.: * . . * .:: :*** :. *: * **:... :.::.*. : .: ** : : *: *. : ::: . :: . : :: *.. :* : . : * **. * : : . . * :: .: : .:. :: ::. : * **:***::: . .* :** .: :* * : * .* ..*:. . * . .*.:..** ::.::** ::. *.***:.:..*::*: * ** * *. .. *: . *. ", "identical_positions": 104, "similar_positions": 173, "identity": "18.77%" }, { "cls_id": "homologset.agr.MGI:1932036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KVX1-1", "uniprot_id": "A0ABK0KVX1_RAT", "id": "A0ABK0KVX1-1", "name": "", "aln": "MGIYCKPSVLFQDSYLLVLTQLLCWVTTMARMCQELCSSDVQETHKPGTKHFAIFPFVPLTATSVSTEGFRVFGPSDPVVVAPGREAILPCSVSPAMSVENMEELRWFRTRFSEAVFVYRDQEEQKEEQMIEYSLRTSLVK-----DQFHEGKAAVRIQNVQESDSGIHVCHFKQGVLYEEAILELKVAAMGSTPEVYIKGPEDGGVCVVCMTSGWYPEPQVHWRDSTGEDLPA-SSETLHEDAEGLFSTETSLVLRDSSVRNVACSIFNPVLGQEKAIAIVIPEPFFPQASPWKAAFIVILTMMGLLVSGTSYLLIREHSGRLKLQQ---EWSHFQLEKDELQTIKEDALRTAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M534-1", "uniprot_id": "A0ABK0M534_RAT", "id": "A0ABK0M534-1", "name": "", "aln": "MGIYCKPSVLFQDSYLLVLTQLLCWVT---------------------------------------TKGFRVFGPSDPVVAAPGREAILPCSVSPAMSVENMEELRWFRTRFSQAVFVYRDQEEQKEEQLPQYSWRTSLVK-----DQFHEGKAAVRIQNVQESDSGIYVCHFKQGHFREEAILELKVAAMGSAPEVYIKGPEDGGVCVVCMASGWYPEPQVHWRDSRGEDLPA-SSETLHEDAEGLFSTETSLVLRDSSVRNVTCSTFNPILGQEKAMAMVIPEPFFPQASPWKAAFLVILTMMGILISGTIYLLRREHSGRLKVQQ---KRKHLQCEKDELQTTKEDALLFTRLFEWGYFDWVLTRVCSFTAWRKAQLYADWRKEHFQACNFTLDPASAHPILNVSQDRMRVTRKDTTMCLDDLFCVLGTNGISSGRYYWEVKLRNRDSS---TWTLGVCREG-VERKGCFSECPEKGFWTVGQSSSGYWAYVDSGRDSLSIRQAPQSVGVFVDYDERNISFYNMSDKSHLFSFHEASFSGTLLPYFRLKSGNISMTVSSMACVSEGQQGEEGRRGRKRSRKGRKGRRPKKGKGLALLPLKESLSPTGEEGLVPGSCVVVSPSGEESPFLQDARDTLFP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2CG29-1", "uniprot_id": "A2CG29_MOUSE", "id": "A2CG29-1", "name": "", "aln": "MENHRKPSLLFHVPCLFVLTQLLSWVT---------------------------------------TQEFRVFGPSDPIVAAPGGEAILPCSVFPAMNVENMEELRWFRSRFSEAVLFYRDQEEQKEGQMPGYSQRTLLVK-----DQFHQGTAAVRILNVQASDSGIYICHFQQGVFYDEAILELKVAAMGSVPEVHIKGPEDGGVCVVCMTSGWYPEPQVHWKDSRGENLTAFSSETHTKDAEGLFSTETLLVVRDSSVRNVTCSIFNPILGQEKATAMFIPEPFFPQASPWKPAFLVTLTMMGLLVLGTSYLLRREHSARLKVQQ---ETVNFQREKDESLKTRDDALRTAGALMVE---RDRRKAAYRAAWKKAQLYADWRKEHFEAWTFTLDPASAHPILAISPDRLSVSRKDSTLCLDDLFCVLGIRGISSGRHYWEVKLRNGDSS---KWTLGVCREG-VDRKGCFSECPHKGFWTVGRSSSGYLAYIDTGTALLSLRQAPQSVGVFVDYTEGDISFYNMSDMSPMFSFHEASFSGTLFPYFRLKSGNVSMIIQSMACASEGREGEDRRRGRKRSRKGRKGKRTKRGKKLVLLPLEESLSPAG-EGLVPGSCVVDSFPEEVSPFLQHARNSLFP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A9L4-1", "uniprot_id": "A0AB13A9L4_DANRE", "id": "A0AB13A9L4-1", "name": "", "aln": "----------MRSIIVLLLLNLLTDCS----------------------------------------VSFTAKVPPGPVVAHVGSTVILPCWISPAQNAE-ALEIRWYRHEDFRYTVLYFQHGKIQDEQEETFRNRSSLTPRSDLSGGLKGGDVSLQLEKIIIQDEALFHCYVNGDSDYSSAELELKVTAPGSAPVLFPRPLDDGRLNVSCSSSGWYPEPNITWTSDQRKTLRP-AAVSLHRAADGLFSVHSWTTVSPSDAQLVSCSVSTTTGESKEGKVDIQGFISSDSSDLWKPLFLTLLICALLGLAGLILYKYRNILTGKKAAGPDGENLPVQERKGYIEVQMSDNAYENASVPVDMNIEDLRKHAEQITIDRENISPDLTVSG-----------------DCKSVRDSPKYHHTAEEFPYQLCAFGAQQFTSGRHYWELELALPPNPPKLSWLIGVVKHKHFSGKDRSALTPSRGFWFLCSDGENGFNTNTDPPITLSISPRPERLGVLLDYDEGLLEFYNVKERKHLLSMHTR-FSGSIVPLFNPGVGDKSPLKIVDCPVEEDSPAELTVPSQSNCSAENITEA---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :::* :** : * . *..*:*. * .**** : ** ..* *:**:* . . ...* :: : :: * : *: *. . :: * .:::: :: .*..:. *:.: . ..* *****:* **.* :. : :** : * * :*******:: * .. : * . :: : . *:****..: .: *..: *:** .. .::. . . .:. **. *:. * : : * *: * : .* .*. .* ", "identical_positions": 68, "similar_positions": 102, "identity": "10.61%" }, { "cls_id": "homologset.agr.MGI:1932038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KVX1-1", "uniprot_id": "A0ABK0KVX1_RAT", "id": "A0ABK0KVX1-1", "name": "", "aln": "MGIYCKPSVLFQDSYLLVLTQLLCWVTTMARMCQELCSSDVQETHKPGTKHFAIFPFVPLTATSVSTEGFRVFGPSDPVVVAPGREAILPCSVSPAMSVENMEELRWFRTRFSEAVFVYRDQEEQKEEQMIEYSLRTSLVKDQ-----FHEGKAAVRIQNVQESDSGIHVCHFKQGVLYEEAILELKVAAMGSTPEVYIKGPEDGGVCVVCMTSGWYPEPQVHWRDSTGEDLPASSETLHEDAEGLFSTETSLVLRDSSVRNVACSIFNPVLGQEKAIAIVIPEPFFPQASPWKAAFIVILTMMGLLVSG-TSYLLIREHSGRLKLQQEWSHFQLEKDELQTIKEDALRTAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M534-1", "uniprot_id": "A0ABK0M534_RAT", "id": "A0ABK0M534-1", "name": "", "aln": "MGIYCKPSVLFQDSYLLVLTQLLCWVT---------------------------------------TKGFRVFGPSDPVVAAPGREAILPCSVSPAMSVENMEELRWFRTRFSQAVFVYRDQEEQKEEQLPQYSWRTSLVKDQ-----FHEGKAAVRIQNVQESDSGIYVCHFKQGHFREEAILELKVAAMGSAPEVYIKGPEDGGVCVVCMASGWYPEPQVHWRDSRGEDLPASSETLHEDAEGLFSTETSLVLRDSSVRNVTCSTFNPILGQEKAMAMVIPEPFFPQASPWKAAFLVILTMMGILISG-TIYLLRREHSGRLKVQQKRKHLQCEKDELQTTKEDALLFTRLFEWGYFDWVLTRVCSFTAWRKAQLYADWRKEHFQACNFTLDPASAHPILNVSQDRMRVTR----KDTTMCLDDLFCVLGTNGISSGRYYWEVKLRNRDSS---TWTLGVCREG-VERKGCFSECPEKGFWTVGQSSSGYWAYVDSGRDSLSIRQAPQSVGVFVDYDERNISFYNMSDKSHLFSFHEASFSGTLLPYFRLKSGNISMTVSSMACVSEGQQGEEGRRGRKRSRKGRKGRRPKKGKGLALLPLKESLSPTGEEGLVPGSCVVVSPSGEESPFLQDARDTLFP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2CG22-1", "uniprot_id": "A2CG22_MOUSE", "id": "A2CG22-1", "name": "", "aln": "MENHRKPSLLFHVSCLFVLIQLLSWVT---------------------------------------TKEFQVFGPSDPIVAAPGGEAILPCSVIPAMNVENMEELRWFRSRFSAAVLVYRDQEEQKREQLPEYSQRTSLVKEQ-----FHQGTAAVRILNVQAPDSGIYICHFKQGVFYEEAILELKVAAMGSVPEVYIKGPEDGGVCVVCITSGWYPEPQVHWKDSRGEKLTASLEIHSEDAQGLFRTETSLVVRDSSVRNVTCSTFNPILGQEKAMAMFLPEPFFPKVSPWKPAFFVTLTMMGLLVLG-TSYLFRRERSARLIVQELTGNLQRVED--NKAEEDTVRTIDALMV---ELAQRKAAYRAAWRKAQLYADWRKEQFQAWTFTLDPASAHTNLAISQDRLTVTR----KDFTRCLEDLSCVLGIRGISSGRYYWEVKLTNIEGS---KWILGVCREG-VVRKNFYFETPRKGFWTVGQSSKGHWAYIDSGRTSLSVRQAPKSVGVFVDYTEGDISFYNMSDMSHMFSFPKASFSGTLFPYFRLRSGNVSMIINSMECASESSEGEEGRRGRKRSRRGGRGGGGRMGRS---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A9L4-1", "uniprot_id": "A0AB13A9L4_DANRE", "id": "A0AB13A9L4-1", "name": "", "aln": "----------MRSIIVLLLLNLLTDCS----------------------------------------VSFTAKVPPGPVVAHVGSTVILPCWISPAQNAE-ALEIRWYRHEDFRYTVLYFQHGKIQDEQEETFRNRSSLTPRSDLSGGLKGGDVSLQLEKIIIQDEALFHCYVNGDSDYSSAELELKVTAPGSAPVLFPRPLDDGRLNVSCSSSGWYPEPNITWTSDQRKTLRPAAVSLHRAADGLFSVHSWTTVSPSDAQLVSCSVSTTTGESKEGKVDIQGFISSDSSDLWKPLFLTLLICALLGLAGLILYKYRNILTGKKAAGPDGENLPVQERKGYIEVQMSDNAYEN-------------------ASVPVDMNIEDLRKHAEQITIDRENISPDLTVSGDCKSVRDSPKYHHTAEEFPYQLCAFGAQQFTSGRHYWELELALPPNPPKLSWLIGVVKHKHFSGKDRSALTPSRGFWFLCSDGENGFNTNTDPPITLSISPRPERLGVLLDYDEGLLEFYNVKERKHLLSMHTR-FSGSIVPLFNPGVGDKSPLKIVDCPVEEDSPAELTVPSQSNCSAENITEA---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :::* :** : * . *..*:*. * .**** : ** ..* *:**:* . ..:* :: : : ** : *:**. . :: * .:::: :: *..:. *:.: . ..* *****:* **.* :: : :** : * * :*******:: * .. : * .: . *:*** ..: .: *..: *:** .. .::. . . . . **. *:. * : : * * . :.: :: : : : ", "identical_positions": 65, "similar_positions": 99, "identity": "10.12%" }, { "cls_id": "homologset.agr.MGI:1932040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6S4-1", "uniprot_id": "SIL1_RAT", "id": "Q6P6S4-1", "name": "Nucleotide exchange factor SIL1", "aln": "-MAPQHLPSTRMAPQGMLLGLLLASCLTFCLSCQNSNNFALTNPEKSTHEDSDTKETRREEELDAEVLEVLNPTQEWQALQPGQAVPAGSHVRMNLQTGVNEVKLQQEDKFQSNWKGFKRGRRLDINTNTYTSQDLKSALAKFKEGTEMENSKDELARQATVKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSS-----SSLEEKVAALFDLEYYVHQMDNAQDLLSFGGLQVVIN--GLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLP-----AKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKV-LAVRVVTLLYDLVTEK-MFAEEEAELTQESS-PEKLQQYRQVQLLPGLREQGWCEITAQLLA------LPEHDAREKVLQTLGALLATCRDRYRQDLELSRTLGSLQAEYQALASLELQEGEDDGYFRELLASIDSLVKELR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPK6-1", "uniprot_id": "SIL1_MOUSE", "id": "Q9EPK6-1", "name": "Nucleotide exchange factor SIL1", "aln": "-MAPQHLPSTRMASPGMLLGLLLTSCLTLCLSCQNSNNFALTNPEKSIHQESDTKETREEEELDTEILEVFHPTQEWQTLQPGQAVPAGSHVRMNLQTGVNEVKLQQEDKFQNNLKGFKRGRRLDINANTYTSQDLKSALAKFKEGTEMENSKDELARQATVKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSS-----SSLEEKVAALFDLEYYVHQMDNAQDLLSFGGLQVVIN--GLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATNQPLP-----AKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKV-LAVRVVTLLYDLVTEK-MFAEEEAELTQDSS-PEKLQQYRQVQLLPGLQEQGWCEITAQLLA------LPEHDAREKVLQTLGALLTTCRDRYRQDLQLSRTLGRLQAEYQALASLELQEGEDDGYFRELLASINSLMKELR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H173-1", "uniprot_id": "SIL1_HUMAN", "id": "Q9H173-1", "name": "Nucleotide exchange factor SIL1", "aln": "-MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLK----GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSS-----SSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVIN--GLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLT-----AKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQEKGTEV-LAVRVVTLLYDLVTEK-MFAEEEAELTQEMS-PEKLQQYRQVHLLPGLWEQGWCEITAHLLA------LPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRTLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B777-1", "uniprot_id": "A0ACD6B777_DANRE", "id": "A0ACD6B777-1", "name": "Nucleotide exchange factor SIL1", "aln": "MLTSRVMANKWRVRFGLTVTFWLLS-LHLIFAHDVKSPTALLIKEDS--DDLNNAEETHLEDEDPEDLEVFRPTDKWQTLRPGQAVPAGSHVRLNLQTGQREVKMGEEEGFK-YWKDGNRQGMMNMDSHSFTAEELKKALKKFKKGADDPVDQQE---EDAVRAKFRPMDELKKDMEALDMLVETDIQVMRRLLDQFNNTN-----STTEEKVAALLDLEYLVHQVDNAQNLVSMGGMSLVIR--YLNSTDVRLQECAAFVLGSAVSSNPSVQVEAVEGGALQKLLTLLATQRPMT-----VKKKVLFAVASLLRHFPFAQSHFLKLGGVQVLSELFQTPGAEA-MRVRIITVLYDMIIEKELISQVGLDIIPDSSHQERLRQYAEVSLLPVLVEQGWCRLVPELLE------SPEHDWREKALRTLLAMMAQCQTQFKQNAGLTASLSELQKQYQELVLTEQDVGEEDGYFGEILTLVDSMVVKMRQV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBV5-1", "uniprot_id": "SIL1_DROME", "id": "Q9VBV5-1", "name": "Nucleotide exchange factor Sil1", "aln": "--------MSGKQVVILLGSVLILGCLQVAAATETDN-----------------------------KTNDFVATDEWQTIAEGQAIPRGLHVRINLQTGLKEAKLLDE---------SERGTSLQSQPDDQNARESHDDNEPLALDYKPDIIEES---IRRVKEQKKSYAELRKAYKEFQKNFRTDGELIVQLIDQFRNFSRTPLESEMRSKLDCLENLEYLLHQIDNALMFIDNGGLDDVLLPIVVNDTSTSLRVSAMRVLGSLASNNPKAQIKVFEKNFGSHLAQILTSSGNVG-----EISAALHAFGALLRKFPLAQQRVLSTSGTQALIKVLQSPDVELRSKAKVVTLISDLVLEKRSVLDVSKDDPEASS---TMAQYVLLDFESWLKTPGYCAAVDTVLTKEFLLLLEQPEVVEQFATALETTEDMCTSTWSQSSGLRHALLTVRNRYAN--STDEYRLEVSQILAKLCERLFNKPKHTEL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08199-1", "uniprot_id": "SIL1_YEAST", "id": "Q08199-1", "name": "Nucleotide exchange factor SIL1", "aln": "MVRILPIILSALSSKLVASTILHSSIHSVPSGGEIISAEDLKELEIS---------GNSICVDNRCYPKIFEPRHDWQPILPGQELPGGLDIRINMDTGLKEAKLNDE-----------------KNVGDNGSHELIVSSEDMKASPGD--------------------YEFSSDFKEMRNIIDSNPTLSSQDIARLEDSF--------DRIMEFAHDYKHGYKIITHEFALLANLSLNENLP--------LTLRELSTRVITSCLRNNP-PVVEFINESFPNFKSKIMAALSNLNDSNHRSSNILIKRYLSILNELPVTSEDLPIYS-TVVLQNVYERNNKDKQLQIKVLELISKILKADMYENDDTNLILFKRN--AENWSSNLQEWANEFQEMVQNKSIDELHTR---TFFDTLYNLKKIFKSDITINKGFLNWLAQQCKARQSNLDNGLQERDTEQDSFDKKLIDSRHLIFGNPMAHRIKNFRDEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . : . : : . ..**.: ** :* * .:*:*::** .*.*: * : :.: : . *: . . : . :: : : : ::.. : : :: : : : :: .:. : :: : *: : .** :: .: . . :::: : . : ::*..:* :. . . .* : : . . ::: :: .:: . : . . : : :: : . *. : . . . : : . . ", "identical_positions": 21, "similar_positions": 117, "identity": "4.29%" }, { "cls_id": "homologset.agr.MGI:1932051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHK4-1", "uniprot_id": "KAT5_MOUSE", "id": "Q8CHK4-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MK2-1", "uniprot_id": "KAT5_RAT", "id": "Q99MK2-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92993-1", "uniprot_id": "KAT5_HUMAN", "id": "Q92993-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDW0-1", "uniprot_id": "A0A8M9QDW0_DANRE", "id": "A0A8M9QDW0-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEPTVEIVEGCRLPVLRKNQENEDEWPLAEILSVKDIPGRKLYYVHYIDFNKRLDEWVTPDRLDL-KKLQFPKKE-AKTPTKNGLPG-----------SRPSSPEREVRKSLDLNVQSASAPSRGKTLPTPKRKAESVSLATQ---VTAATPVPSLPSS--AEASQASVYPAMRDSSF-SIKAREEHEQLTSLTTNGTTRRLIPSQPGRKRK-NCVGTEEIVKVFQNNSPRSSTVYLPPGEDSQDSSDGIPSAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLVRAVLGPDVTHSQHQIKTKCNLRHPPGNEIYRKGTISFFEIDGRKNKMYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMNLK-SENGERPQMTINEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHERAMHKRHLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q960X4-1", "uniprot_id": "TIP60_DROME", "id": "Q960X4-1", "name": "Histone acetyltransferase Tip60", "aln": "MKINHKYEFDDDVASICESTAALTEGCRLPVR---MHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKRLDEWVNEEDLYT-RKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSG----ALAAIPQTPTGASGSVPPPAGIPNSVAPPGTPSSGGELVNGNNLAAALQKRINRKRKNHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAAND----------------------DGDGSQDGKTPTPRQSGSMVT--HQDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLS-----------------KCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTPKDWSK---RSK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08649-1", "uniprot_id": "ESA1_YEAST", "id": "Q08649-1", "name": "Histone acetyltransferase ESA1", "aln": "--MSHDGKEEPGIAKKINSVDDIIIKCQCWVQ-----KNDEERLAEILSINTRKAPPKFYVHYVNYNKRLDEWITTDRINLDKEVLYPKLK--------------------------------------------------------------------------------------ATDEDNKKQKKKKATNTSETPQDSLQDGVDGFSRENTDVMDLDN-------LNVQGIK----------------------DENISHEDEIKKLRTSGSMTQN---PHEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERYRK-----------------KCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPEKPLSDLGLLSYRAYWSDTLITLLVEHQ-------KEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHIIFLNEDILDRYNRLKAKKRRTIDPNRLIWKPPVFTASQLRFAW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: * : *: ****:*:: . :****:::*******:. : : ::: :*: . . . . . . * : * :. * :**:. . ::*::*:: * :*::.::******** ** :*: :* *:* * * :*: ** ***********. :*********:: :.:*****:* **********.****** **. * *.*:**********::.********:* *** *************** *.*.*:**************:**::*:: ::: : :**::*.. **:.. *:: * : **::.*****:*: :.. *:: :.* *: **.: * :.* :: * ", "identical_positions": 175, "similar_positions": 111, "identity": "29.46%" }, { "cls_id": "homologset.agr.MGI:1932052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6RY07-1", "uniprot_id": "CHIA_RAT", "id": "Q6RY07-1", "name": "Acidic mammalian chitinase", "aln": "-------------MAKLILVTGLVLLLN----------------------------------------------------------------VQLGSAYN--------------------------------LVCYFTNWAQYRPGLGSFKPDDINPCLCTHLIY-AFAGM-QNN-QITTIE-WNDVT------LYKAFNDLK--------------------------NRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQ--DKHLFTVLVKELREAFEQEAIESNRPRLMVTAAVAAGISNIQAGYEIPELSQYLDFIHVMTYDLHGSWDGYTGENSPLYKLPTETGSN----AYLNVDYVMNYWKDNGAPAEKLIVGFPEYGHTYILSNP-----SDTGIGAPTSGNGPAGPYTRQAGFWAYYEICTFLRNG---ATQDWDAPQEVPYAYKGN-------EWVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCD-QGKFPLTSTLNKALD-------IPTAGCTAPDLPSEPVTTPP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSGS-------------------------------------------------------GGGSSGGGSEG-------------------------------------------------------------------------SGFCAGKADGLYPVADDRN----------------------------------------------------AFWHCINGITYQQHCQAGLVFDTSCNCCNWP---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XA9-1", "uniprot_id": "CHIA_MOUSE", "id": "Q91XA9-1", "name": "Acidic mammalian chitinase", "aln": "-------------MAKLLLVTGLALLLN----------------------------------------------------------------AQLGSAYN--------------------------------LICYFTNWAQYRPGLGSFKPDDINPCLCTHLIY-AFAGM-QNN-EITTIE-WNDVT------LYKAFNDLK--------------------------NRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQ--DKHLFTVLVKEMREAFEQEAIESNRPRLMVTAAVAGGISNIQAGYEIPELSKYLDFIHVMTYDLHGSWEGYTGENSPLYKYPTETGSN----AYLNVDYVMNYWKNNGAPAEKLIVGFPEYGHTFILRNP-----SDNGIGAPTSGDGPAGPYTRQAGFWAYYEICTFLRSG---ATEVWDASQEVPYAYKAN-------EWLGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCD-QGKFPLTSTLNKALG-------ISTEGCTAPDVPSEPVTTPP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSGS-------------------------------------------------------GGGSSGGSSGG-------------------------------------------------------------------------SGFCADKADGLYPVADDRN----------------------------------------------------AFWQCINGITYQQHCQAGLVFDTSCNCCNWP---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZP6-1", "uniprot_id": "CHIA_HUMAN", "id": "Q9BZP6-1", "name": "Acidic mammalian chitinase", "aln": "-------------MTKLILLTGLVLILN----------------------------------------------------------------LQLGSAYQ--------------------------------LTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIY-AFAGR-QNN-EITTIE-WNDVT------LYQAFNGLK--------------------------NKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGSRGSPPQ--DKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSN----AYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNP-----SNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNG---ATQGWDAPQEVPYAYQGN-------VWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCN-QGKFPLISTLKKALG-------LQSASCTAPAQPIEPITAAPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSGNGS-------------------------------------------------------GSSSSGGSSGG-------------------------------------------------------------------------SGFCAVRANGLYPVANNRN----------------------------------------------------AFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZV2-1", "uniprot_id": "Q9VZV2_DROME", "id": "Q9VZV2-1", "name": "", "aln": "--------MFPPRLLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITSATTTSARRTRLRSKAKLGAAAAGGAAVAAGGTALVASGSSLKGKKTKVDDGTPKIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIF-AFGWL-KKN-KLSSYE-SNDETKDNVPGLYERMMTLK--------------------------KANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYP--KGS--D--DKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWERETGHNAPLYAPSTDSEWR----KQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANP-----DKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLNG---AVYVWDDEMKVPYLVDGD-------QWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREELLGISRGKEAKDVNWTAVAATFEDIEEKPEPIKISVDEILNKVRKPQVQKKQRIKSGANAVASNTRPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEATDDDPENYESVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYPRGAEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQVPFAYRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALNDELKDYKVELEYDGPYESHGPRGAYTTKDPHDVTCAEEDGHISYHKDWADCTHYYMCEGERKHHMPCPANLVFNPQENVCDWPENVEGCHTPTEAPA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M6-1", "uniprot_id": "Q9W2M6_DROME", "id": "Q9W2M6-1", "name": "chitinase", "aln": "-----------MKLVSIWALAALCLCLGQ---------------------------------------------------------------VAS-SEKL--------------------------------LNCYWGTWANYRPGDGKFTPSDIDPSLCTHISY-TFFGI-SDAGEFKSLDTWLDMDD--GLGFISQTIALK--------------------------QRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEA--DRENFVTLLREIKETYDQYGLELG-------IAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESID----------------YWLSHGAPAEKLILGIGFYGHSYQMSDS-----SQNWPGAACIGPGTAGVYTRENGFLGYHEICLNN------WQTVFDQENGAPYAFQGD-------QWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCG---ESYPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSSPT-------------------------------------------------------PAPTPGGGSGG----------------------------------------------------------------------------NECAQDGFFVLESDCN----------------------------------------------------KFYQCVGGVRYDFQCGAGLCFNTITLNCDWP---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M5-1", "uniprot_id": "Q9W2M5_DROME", "id": "Q9W2M5-1", "name": "", "aln": "-------------MGKLLALLAV-LCLSQ---------------------------------------------------------------VIG-AERI--------------------------------VNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSY-SFFGI-NDNGEIQSLDTWLDYD----LGFINQAISLK--------------------------NQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNHGFDGLDLDWEYPNQRGGNWN--DRANFVTLLREIKEAFAPYGYELG-------IAVGAGESLASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVENAIN----------------FWLSQGAPANKLVLGVGTYGRSFQLSDS-----SQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNN------WHTVFDYDNAAPYAYSGD-------QWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCG---ETYPLLKTINRKLRW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M7-1", "uniprot_id": "Q9W2M7_DROME", "id": "Q9W2M7-1", "name": "chitinase", "aln": "-------MWSVSGLVKLLLGVILMAASSS---------------------------------------------------------------AQGNSSKN--------------------------------VVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIY-AFLGI-EETGQLRVIDAYLDLEENSGRGNIKSFNALK--------------------------LKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNE-DRSNYITFLKELKEGLEPFGFILS-------AAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATA-----EGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMEREE--WTQKWEATQQVPYAYRQR-------QWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQ--QPYPLLHEINRVLFG--------------------GNTPSG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTTES-------------------------------------------------------NRESPSEGFSC----------------------------------------------------------------------------PADAPAGYIRDPDNCS----------------------------------------------------KFYYCSGGKTHNFDCPSGLNFDLDTKSCNYSGSVKC----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFR3-1", "uniprot_id": "Q9VFR3_DROME", "id": "Q9VFR3-1", "name": "chitinase", "aln": "-------------MVRYIPLLLLGVLCSWP--------------------------------------------------------------AATVASDQAS-----------------------------RIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIY-SFIGVNDKSWDVLVIDPELDVDQ----GGFSKFTQLK--------------------------KSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREGRGWEIT-----MAVPVAKFRLNEGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQYAY----EKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKN-YNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWTVEWDDAGMVPYTYKDT-------QWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCGR---KNGLTQILYDNMKNYRVPEPTRQTTPRPEWAKPPATPPNPDEGAVVAPTTSTTKRPKPKPKPTSSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPTSAPG------------------------------------------------------PVPTVGSSTPK----------------------------------PTTKKPKKPKKTTTTTTTTPAPEKSTEEPEEVVYPVDPVEPTDPEQPMGPQFDPNEIDCTNRDFVPH---------------------------------------PNCRKYFRCVHGKPVEFECKEGTAFHTVLNVCDWIENSDRYYCSRMKNKEKGNEAH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MLW8-1", "uniprot_id": "Q8MLW8_DROME", "id": "Q8MLW8-1", "name": "", "aln": "-----------MTSFQYVFMIMIFLICGCI--------------------------------------------------------------AKEYN-----------------------------------VFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEK----DKLSSVKTMK--------------------------WDS-IKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYP--TLLGGHPDDRQNFVILLEELGLIFRKN-QLILMV-----AVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEG------------SVTDSIMHWKRNGGAPEKLILGIPLFVRSFTMDR------NQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSK----WSRMFDQLAKVPYATRGD-------QWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGE---QHGLLRVIFSALG-----DKNGLTTEKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTEASG------------------------------------------------------LCPHDGFSRDG----------------------------------WDCR---------------------------LYHECRDGERIYYECLEGQYFDENQIVCR----------------------------------------------------------PAAEVKCDQ--------NFVIWRPGMPVYSYDNMPLNLKIVE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W092-1", "uniprot_id": "CHIT2_DROME", "id": "Q9W092-1", "name": "Probable chitinase 2", "aln": "---MTLRSRLSGEAPQLWLLLLLASTASS-------------------------------------------------------------LWASVAARTG--------------------------PLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVY-AFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLK--------------------------RSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPA--DRENFVLLTKELREEFDEHGLLLT-------SAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDP---------LSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLAS-------GFLNDVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEATMLAVDELAVPE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQPDDSENE-------------------------------------------------------------------------------IPHGSIADRKNAG-----------------------------------------------------------ASMVSLGLGVTAVFMLLHRLAQ-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06350-1", "uniprot_id": "CHI2_YEAST", "id": "Q06350-1", "name": "Sporulation-specific chitinase 2", "aln": "MVGHSAQHRSKSSLVSHLLILLIFITIIIEMCLYN------------------------------------KIFKNQRSDDIRDNFNNGGHRVPSNVQNHG----------------------THIRDEAFISGVYYSNWSPYKPR--FHFPHDINLKQVSHIYY-AFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLGCIGELFYLKNTCSDKKFKVIMSIGGWSD-SENFKIIIKDDKLLQNFVDSSVETMFRLGFDGIDLDWEFPGNNESEPR--GYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSETTGYHSNLFSETELNG----------NFAMHYMIDRFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKYVSAYCFDEKNS-----IFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYANESRS------LINAFNEGLHFN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSSKPSIFQDVRVK------------------------------------------------------------KYYLNKYGDGGFLSPYLKHLDSRKQ-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . .. :*: : . : : * :*** :. : * : . ***.::**.:* . : . : : : * :* :: * .**::*. : :.: * :: : ::. :. * . .* : * : : . . ", "identical_positions": 23, "similar_positions": 54, "identity": "2.12%" }, { "cls_id": "homologset.agr.MGI:1932075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35083-1", "uniprot_id": "PLCA_MOUSE", "id": "O35083-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "aln": "MELWPGAWTALLLLLLLLLS---TLWFCSSSAKYFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHAKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLP--DRCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHN--GSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKERRFTSPGRCQVRVLPPVSTEGLTPDDVPALADSVRHSMLTIFREISTDGLGGGDCLKKP-----------------------------------------------------GGAGEARL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99943-1", "uniprot_id": "PLCA_HUMAN", "id": "Q99943-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "aln": "MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP--GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHN--GSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTS-GQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKP-----------------------------------------------------GGGG--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYJ4-1", "uniprot_id": "Q9VYJ4_DROME", "id": "Q9VYJ4-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "MITMTSFIELLGLFLLLMLP---FLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVSTLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAWLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTRRNT--GALHPFKKGAFHMAIDQQIPILPVVFSSYCTFLNDKKKILNS-GRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYKPIKKVGIPAASSASTSSTTTTTLASPGTAVTPVADAAVAAAAAVASSSSAYGQPPGYEAGAAKASLLKTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33333-1", "uniprot_id": "PLSC_YEAST", "id": "P33333-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "-------MSVIGRFLYYLRS--------------VLVVLALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAK-KPYIMIANHQSTLDIFMLGRIFP--PGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNR-GCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVN------------------THNEGSSVKKMH---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : . * : : * .: : . : *: :: * .::. :. ::::****:**:: : .: *. **:.* :. * *:* *:** : .* ..:.. . : .: :******** . :: ***:****:* : ::**:*:*.*. : * :. * : * *:.**.** *.: : : ** .*: :: . . : *.. ", "identical_positions": 55, "similar_positions": 83, "identity": "15.76%" }, { "cls_id": "homologset.agr.MGI:1932093", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q78E65-1", "uniprot_id": "JDP2_RAT", "id": "Q78E65-1", "name": "Jun dimerization protein 2", "aln": "-------------------MMPGQIPDPSVTAGSLPGLG-PLTGLPSSALTTEELKYADIRNIG-------AMIAPLHFLEVKLGKRPQ---------------------------------------PVKSEL-------------------------------------------------------------------DEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRH----RPTCIVRTDSVRTPESEGNPLLEQLDKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97875-1", "uniprot_id": "JDP2_MOUSE", "id": "P97875-1", "name": "Jun dimerization protein 2", "aln": "-------------------MMPGQIPDPSVTAGSLPGLG-PLTGLPSSALTTEELKYADIRNIG-------AMIAPLHFLEVKLGKRPQ---------------------------------------PVKSEL-------------------------------------------------------------------DEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRH----RPTCIVRTDSVRTPESEGNPLLEQLDKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WYK2-1", "uniprot_id": "JDP2_HUMAN", "id": "Q8WYK2-1", "name": "Jun dimerization protein 2", "aln": "-------------------MMPGQIPDPSVTTGSLPGLG-PLTGLPSSALTVEELKYADIRNLG-------AMIAPLHFLEVKLGKRPQ---------------------------------------PVKSEL-------------------------------------------------------------------DEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRH----RPTCIVRTDSVKTPESEGNPLLEQLEKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T6A9-1", "uniprot_id": "A0AB32T6A9_DANRE", "id": "A0AB32T6A9-1", "name": "", "aln": "-------------------MMPGQIPDPSVTAGSLPSLG-PLAGISATTLS-EHLKYADLCHIG-------AMLSPLHLLG-KLGKRTL---------------------------------------PIKAEK-------------------------------------------------------------------DEEEERRKRRREKNKVAAARCRNKKKERTEYLQKESERLEMMNSELKAQIEELKHERQQLILMLNRH----RPTCIVRTDSIKTPEKEANPLLEQAEAK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DGM8-1", "uniprot_id": "JDP2_DANRE", "id": "Q6DGM8-1", "name": "Jun dimerization protein 2", "aln": "-------------------MMPGQIPDPLVTAGSLPSVG-PLAGFPATTLT-EQLKLAELYRLG-------TVLSPLMLNR--HAKRPFD--------------------------------------AIKSED-------------------------------------------------------------------DDDDERKKRRREKNKVAAARCRNRKKERTDFLQKESERLEMLNSDLKSQIEELKSERQQLIVMLNLH----RPTCIVRTDSVKSDE---HPLEPRED---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZS8-1", "uniprot_id": "ATF3_DROME", "id": "Q9XZS8-1", "name": "Activating transcription factor 3", "aln": "MFNSNIPASSLLSIDSGGLLMGGHTPKTPEILNSLIAMTNPLENFSYSSAAAAAAAVSVASSSASCSAASTPVVTVRHFNGHPNGQSHSQDSSHSSCSGSPLDSPAGTATTPSVQQTCSRLIKEGLKLSIQSKRKLSTCDSSSGSEQPHSKYSRRSSNHNGHSGSSNNYSGSMSNANDLDDDCEESSDDDSETKSQPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVELKNQVRQLETERQKLVDMLKSHGCQRAGGCQLPSQLLQSPAQKYLSELELETVSIDGPNSGNNNQRLQSIPSMATFKYGSKTAAAMAQQLPNGYCKPSPSAQEFEHAGYQQQQQQQQQQQPQSLNPAGNNVIDQQHANPSPSLLSDYVPNCDGLTGSASNHPSHNNNNNNNNSSGASSNTSNNNSNISSHSSNATSSTTPTATSSAIEFVKNELVDSQSPYTTALSAERFLFEPSDGFPDIKHACVLPSPCGINGLNMASVVNTNGSTGNNNNSHHNNNNNNNNHLMDFHQGLQHGNIGTGVGVGVGVGVGVGVGVGVMTPYDDEQLLLLKNGCFATDLLSQLVEEGGEYVDLDSATAFMNNGSCLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *: *.. .** .: ** .:. :: : : . .::: : .: .:::: ::::*::****:**:**::** :*:***: * :*** *: * :** *:.:*: ***:*: **: * * : :: ::: . ", "identical_positions": 40, "similar_positions": 57, "identity": "6.53%" }, { "cls_id": "homologset.agr.MGI:1932094", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GUQ1-1", "uniprot_id": "EGFL8_MOUSE", "id": "Q6GUQ1-1", "name": "Epidermal growth factor-like protein 8", "aln": "MGLWAELCISLRGLSFFLVLMTGEGTRGGSFKESLGVCSKQTLLVPLRYNESYSQPVYKPYLTLCAGRRICSTYRTTYRVAWREVRREVPQTHVVCCQGWKKPHPGALTCDAICSKPCLNGGVCTGPDRCECAPGWGGKHCHVDVDECRASLTLCSHGCLNTLGSFLCSCPHPLVLGLDGRTCAGGPPESPTSASILSVAVREADSEEERALRWEVAELRGRLEKLEQWATQAGAWVRAVLPMPPEELRPEQVAELWGRGDRIESLSDQVLLLEERLGACACEDNSLGPSLRG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MG84-1", "uniprot_id": "EGFL8_RAT", "id": "Q6MG84-1", "name": "Epidermal growth factor-like protein 8", "aln": "MEPWAGCCIFLRGFSFLLVLMT-EGAKGGPFKESLGVCSKQTLLVPLRYNESYSQPVYRPYLTLCAGRRICSTYRTTYRVAWREVRREVQQTHVVCCQGWKKPHPGALTCEAICSKPCLNGGVCAGPDQCECASGWAGKHCHVDVDECRTSLTLCSHGCLNTLGSFTCSCPNPLVLGPDGRACAGGPPESSTSAGILSVAVREADSEE-HALRREVAELRGRLERLEQWATQAGAWVRAVLPVAPEDLRPEQVAELWGRGDRIESLSDQVLLLEERLGACSCEDNSLGPGLHG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99944-1", "uniprot_id": "EGFL8_HUMAN", "id": "Q99944-1", "name": "Epidermal growth factor-like protein 8", "aln": "MGSRAELCTLLGGFSFLLLLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKPYLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSASILSVAVREAEKDE-RALKQEIHELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQVAELWGRGDRIESLSDQVLLLEERLGACSCEDNSLGLGVNHR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * * *:**:*:*:. **::**.::** ********:***:**********:***************** *** ******** ***.******** *******:***:*********. **:****.**.************:*:***** *:** *** *.**: **** ***:* *.**..***.*********:.:* :**: *: *******:***** ***********:.**:*:*******************************:******* .:. ", "identical_positions": 220, "similar_positions": 45, "identity": "74.83%" }, { "cls_id": "homologset.agr.MGI:1932101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAR9-1", "uniprot_id": "A0A8I6AAR9_RAT", "id": "A0A8I6AAR9-1", "name": "Ankyrin repeat domain-containing protein 17", "aln": "MEKATVP----AAAEGEGSPPAAAAVAAPP--AAAEVGG------GARSASSPRGMVRVCDLLLKKKPPQQ------PHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGG-----TSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLAAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVAATLPVRNKAASKQKSNSHLPANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKIEELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSCQHLGLLTSVGVGEPLPEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLAAGPLPPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMAAVSGRASAMSNTPTHSIAASVSQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKHKVEEEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKASGESKSSSTSESGDSDNMRISSCSDESSNSNSSRKSDNHSPAVATATVASKKQPSVLVTFPKEERKSVSGKASIKLSETVNEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGPKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANSSLMGIKMTSVALSSTSQTATALTVPAVSSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASAVPGTTSNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNSTAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKGASSSEQEASSPPVVETTNSRPSHSSTSSGSSSGHSTQQQPPGSVPQEPRPPLQQSQVPSPDVRMTVPPTATSSAPVVVPSTAPMTYPMPQTQMGCSQP-PKMETPAIRPPSHGTTAPHKNSAPVQNSSVAVLNVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPVAPNFSAPLPFGPFSTLFENNPTNAHAFWGGPVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDTPYGSVTPSSTHLGNFASSLSGGQMYGPGAPLGGAPIGGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNESPAQSVSSGVRAPSPAPSSVPLGSEKPSSVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKLGSMPFSVYGNAMLPPVAPIPDGAGGPIFNGPHSADPSWNSLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NH0-1", "uniprot_id": "ANR17_MOUSE", "id": "Q99NH0-1", "name": "Ankyrin repeat domain-containing protein 17", "aln": "MEKATVP----AAAEGEGSPPAAAAVAAPPAAAAAEVGG------GARPASSPRGMVRVCDLLLKKKPPQQQQQQQPPHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGG--TSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLAAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANLAATLPVRSKAASKQKSNSHLPANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKIEELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQ-------------------------SCQHLGLFTSVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLATGPLPPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMAAVSGRASAMSNTPTHSIAASVSQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEEEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNSNSSRKSNNHASAVVTTTMASKKQPSVLVTFPKEERKSVSGKASIKLSETVNEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGPKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKSSTANSKIGSSAPTTTAANSSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTASSSASAVPGTTSNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNSTAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKGASASEQEASSPPVVEPANSRPPHSSSSSGSSSGHSTQQQPPGSVPQEPRPPLQQSQVPSPDVRMTVPPTATSSAPVAVPSTAPVTYPMPQTQMGCSQP-PKMEAPAIRPPSHATAAPHKTPAPVQSSSASVLNVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPVAPNFSAPLPFGPFSTLFENNPTNAHAFWGGPVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDTPYGSVTPSSTHLGNFASSLSGGQMYGPGAPLG-----GAPLGGAPTAANFNRQHFSPLSLLTPCSSASNESPAQSVSSGVRAPSPAPSSVPLGSEKPSSVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVGSMPFSVYGNAMLPPVAPIADGAGGPIFNGPHSAEPSWNSLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75179-1", "uniprot_id": "ANR17_HUMAN", "id": "O75179-1", "name": "Ankyrin repeat domain-containing protein 17", "aln": "MEKATVPVAAATAAEGEGSPPAVAAVAGPP--AAAEVGGGVGGSSRARSASSPRGMVRVCDLLLKKKPPQQ------QHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAASKQKSSSHLPANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKIEELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQ-------------------------SCQHLGLLTPVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLAAGPLPPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMAAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNSNSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQMYGPGAPLG----------GAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVGGMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* :**********.****.** ******* **.********************** *********************************** **************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************:******************************************:*:***:*.********.*********************************************************************************************************************** *******:*.***** *.*******************************************:**********************************************************************************:****************************************************************************************************************************************************************************************************************************************************************************************************:********************************* ************************************************************************************************************************************************ ***:*************************************************************************..***********************************:**:.**.*:*::******************************:.********************************* *************************************** **********************************************************:****************:********:*****************:*******************************************************************************************************************:*****:****::***********************************.************************************************* **:*****.******.:*:**.:**:******.**.********.*************.*:******* *******.******:******* ***.** ****:******.*.*:****..*.**.**.:**.************************************:*******************.**.*******.******************************************************:*****************.:************* ***:***********************:*.**************************.***************************************************************************************************************:*.**********:******.************:*:****************************************", "identical_positions": 2496, "similar_positions": 81, "identity": "94.33%" }, { "cls_id": "homologset.agr.MGI:1932115", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVP6-1", "uniprot_id": "PAPOB_MOUSE", "id": "Q9WVP6-1", "name": "Poly(A) polymerase beta", "aln": "-------MMPFAVTTQGAQQPAPAPKQFGISSPISLAAPKDTDRELTQKLIETLQPFGVFEEEEELQRRILILQKLNNLVKEWIREISESRNLPQAVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRNDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDSFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMIEEFKQGLAITHEILLNKAEWSKLFEAPSFFQKYKHYIVLLASAP-TEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ETADKEE----------------FRTMWVIGLVLKKPENSEILSIDLTYDIQSFTDTVYRQAINSKMFEMDMKIAAMHLRRKE-LHQLLPNHVLQK-KETHLTE----------------------------------------SVRLTAVTDSSLLLSIDSENSMTAPSPTG--------------TMKTGPLTGNPQGR-NSPALAVMAASVTNIQF---PDVS-----------LQHVNPIESSGIALSESIP---QIPSQPTISPP-----PKPTMTRVVSSTHLVNHPSRPSGNTATNIPNPILGV-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRJ5-1", "uniprot_id": "PAPOB_HUMAN", "id": "Q9NRJ5-1", "name": "Poly(A) polymerase beta", "aln": "-------MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLASAS-TEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ENPDMEE----------------FRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMGMKITAMHLRRKE-LHQLLPHHVLQD-KKAHSTE----------------------------------------GRRLTDLNDSSFDLSAGCENSMSVPSSTS--------------TMKTGPLISSSQGR-NSPALAVMTASVANIQA---TEFS-----------LQQVNTNESSGVALNESIP---HAVSQPAISPS-----PKAMVARVVSSTCLISHPDLQETQQQTYL---IL-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B770-1", "uniprot_id": "A0A8M2B770_DANRE", "id": "A0A8M2B770-1", "name": "Poly(A) polymerase", "aln": "--------MPFPITSQ-VQTAQPTPKHYGITSPISLAPPKEADLVLTRKLTETLRPFGVFEEELELQRRILVLGKLNTLVKFWIREVSEAKNIPASVIDSVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERTDFFSSFYEKLKEQEEVKDLRAVEEAFVPVIKLAFDGIEIDILFARLALQTIPENLDLRDDGLLKNLDIRCIRSLNGCRVTDEILHLVPNIENFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAVAATLVHKFFLVFSKWEWPNPVLLKQPEDCNLNLPVWDPRVTPSDRYHLMPIITPAYPQQNSTYNVSASTRAIMVEEFKRGLAITDEILQNKADWSKLFEAPNFFQKYKHYIVLLASAQ-TEKQHLEWVGLVESKIRILVGNLEKNEFITLAHVNPQSFPGPK--------EGNDKEE----------------FSTMWVIGIVFKKMEGSENLNVDLTFDIQSFTDTVYRQAITSKMFEQDMKITAMHVKRKQ-LHQLLPEVAIHRSKRKHSSD----------------------------------------GVR--AMNDSNLDLSLDSDNSMSVPSPTGPSAAKIARAPSPQGSTGTATNTSELQGKTEATGENTHLASVDGTSS---SNAS-----------GKEAAPPQSTSPIQSEKKPSEQNPLPSPCLSAEPAVKRPASALENEMTKKAKVEDLSAPEAKSSGETDGHVAPAQIVEVIPSDGELKTET----------ELMVEDTAEKVPLAQKTSN---------ADLSDVPVLPNNPIPVVKNSIKLRLSR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG96-1", "uniprot_id": "A0A0B4KG96_DROME", "id": "A0A0B4KG96-1", "name": "polynucleotide adenylyltransferase", "aln": "MWNSEPTHRQHHQHNGNSTSGGPPAKQLGMTSAISLAEPRPEDLQRTDELRGSLEPYNVFESQDELNHRMEILAKLNTLVKQWVKEISVSKNMPESAAEKLGGKIYTFGSYRLGVHHKGADIDALCVAPRNIERTDYFQSFFEVLKKQPEVTECRSVEEAFVPVIKMNFDGIEIDLLFARLSLKEIPDDFDLRDDNLLRNLDHRSVRSLNGCRVTDEILALVPNIENFRLALRTIKLWAKKHGIYSNSLGYFGGVTWAMLVARTCQLYPNAAAATLVHKFFLVFSRWKWPNPVLLKHPDNVNLRFQVWDPRVNASDRYHLMPIITPAYPQQNSTFNVSESTKKVILTEFNRGMNITDEIMLGRIPWERLFEAPSFFYRYRHFIVLLVNSQ-TADDHLEWCGLVESKVRLLIGNLERNPHIALAHVNPKCFEFKKGQSANNSQNNSGNEDDLKQSQGNQSAVTSAPFCSMWFIGLEFER---SENLNVDLTESIQNFTEHVMMHGVNIKMLKEGMTIDARHVKRKQ-LSLYLDSDFLKRERKSMESHNNFNNTLLANRKRLSTELAQSQDPLPPGQQPSSGNRGRDSGAKIQRLSDSLTEENSNASSDMGAGTPTTPTTAQLS-APSFKSSGKNGSEIDVVEQEPTQPHNNGNASSNTTTTE---VACSXQPPTLHPHPPHQQPPPAPPQPPAHHHHHQKFRKNNNAAAAAASNSIFNQRSILHAASSLSAALSITGHKRKQQTATSTTMISSSNIAHSNYTQHSTHNNNGGGGGSHYNKTYYIDDDDEDNNQPLLTPNNQTQQQQKAVRITATSASPATSVPVAASAAPPAPTISL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29468-1", "uniprot_id": "PAP_YEAST", "id": "P29468-1", "name": "Poly(A) polymerase", "aln": "---------------------MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQETANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARLDQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMKLEVLAGIKIAHPFTKPFESSY---------CCPTED------------------DYEMIQDKYGSHKTETALNALKLVTDENKEEESIKDAPKAYLSTMYIGLDFNIENKKEKVDIHIPCTEFVNLCRSFNEDYG---------------------------------------------DHKVFNLALRFVKGYDLP----------------------DEVFDENEKRPSKKSKRKNLDARHETVKRSKS----------------------------------------------------DAASGDNINGTTAAVDVN-----------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : *::..:* . . : . * *. . ** : * .*: :* *: *.: :: *:* :.:. . . ****:*:******** *:***:* *.* :: * *:* * *: : *: : .* :****:**: *.**.**:: *** :* .: * *..**:*** : :*:*** ******* ***: : **::**:*****: : :*:* :*: ***:******* ******* ::.::.:**:::*.*:**:**:** :: *.. **:*:: ..** * **:******. :*.*:: **: ::: ** :*: **.:*: .: * .*** .** :*:.:: : . : : .:**:* ******:*:*: .** * :** .: * *: .* . *. :. : .. . : : : .:*: : : : . . .. .. . : . : . . :. ", "identical_positions": 168, "similar_positions": 165, "identity": "20.1%" }, { "cls_id": "homologset.agr.MGI:1932118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35449-1", "uniprot_id": "PRRT1_MOUSE", "id": "O35449-1", "name": "Proline-rich transmembrane protein 1", "aln": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGLASAAASAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLG--GYVAPGYPLQLQPCTAYVPVYPVGT---PYAGGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MG82-1", "uniprot_id": "PRRT1_RAT", "id": "Q6MG82-1", "name": "Proline-rich transmembrane protein 1", "aln": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGLASAAAGAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLG--GYVAPGYPLQLQPCTAYVPVYPVGT---PYASGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99946-1", "uniprot_id": "PRRT1_HUMAN", "id": "Q99946-1", "name": "Proline-rich transmembrane protein 1", "aln": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLG--GYVAPGYPLQLQPCTAYVPVYPVGT---PYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R6N6-1", "uniprot_id": "F1R6N6_DANRE", "id": "F1R6N6-1", "name": "", "aln": "MSSEKHGLEEAAGRQ---PMSQPMMQMAPPPYLPTQDPNMPPH-------------------------------PPPPGCAPQPNYPPPP------PPPG--------SDGYLQETQFH--------SGTLGPQGAPN------GYPVQTHG-PVGTVPHPPVGYLHPGYPLQLQPCTAYVPVYPIGTGAQPYMPNGAPHPGVAPGQMAMHMPNGIALMESRRPPHDYLPIAVLTTVCCFWPTGIIAIIKAVQVRTAIARGDMVTAEIASREARNFSFISLAVGIASIVLCTILTVVVIIASQHHDDDWEP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ** ::. : * . * ** * *. * *.... *:* : .** **** .* *****:*. :.: * ** *: * **. .***:* **: ******************:** ** . . .**:. . *:**:*.*******:*******:***********:********:****:*:*********************::*********:***:***:: *:*", "identical_positions": 147, "similar_positions": 47, "identity": "47.27%" }, { "cls_id": "homologset.agr.MGI:1932127", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG81-1", "uniprot_id": "FKBPL_RAT", "id": "Q6MG81-1", "name": "FK506-binding protein-like", "aln": "METSLISPMKENNTAQPQQ-REENTQQNLNAAVPIKQQSPGLLPEALEVGVKPDPASQILA-TQEIENPVAGFEGDSDKFHISTDEMAEHLQASDLWYCPDGSFVKKIIVHGHGLDKPKLGSKCRVLALGFPFGSGMPEGWTELTIGTGQWREKTWGELTEKCLESMRQGEEAKIHLPGSSTPLAKLRLDSFTNGRDSWELEAVEKEALAKEEHRRGTELFRAGNPQGAARCYGRALRLLLTLPPPGPPERTILHANLAACQLLLGHPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGDLDKATADLKKVLAVDPKNRAAKEELGKVVIQGKIQDAGLARGLRKMFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35450-1", "uniprot_id": "FKBPL_MOUSE", "id": "O35450-1", "name": "FK506-binding protein-like", "aln": "METSPISPMNEKNTAQPQQ-REENAQQILNTAIPFRQRSPGLLPEALKVGVRPDPANQIVE-TQEIEHPVAGFEGDSDQFQVSTNEMAEHLQASDLWYCPDGSFVKKIIVPGHGLDKPKLGSKCQVLALGFPFGSGMPEGWTELTIGIGQWREKMWGELMEKCLESMRQGEEAKIHLPGSSAPLAKLRLDSFTNGRDSWEMEAMEKEALAKEEHRRGTELFRAGNPQGAARCYGRALRLLLTLPPPGPPERTTLYANLAACQLLLGHPQLAAQSCDRVLEREPGHLKALYRRGVARAALGDLEKATADFKKVLAVDPKNRAAKEELGKVVIQGRKQDAGLARGLRKMFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIM3-1", "uniprot_id": "FKBPL_HUMAN", "id": "Q9UIM3-1", "name": "FK506-binding protein-like", "aln": "METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. :..: *::*:**** *:* :: *::.: ::*:. . .*:*:: * ****.**: ** *: ** :****.: : **.:*.* ******************:: *********** *:*********** ********:* * ***: **** ******* *****:::*** * * .:* * ***:******:*: ******:**: ***********:************************* *:***********:****************************:****:*:*****:*****:*******:**********: ******:******.", "identical_positions": 250, "similar_positions": 61, "identity": "71.63%" }, { "cls_id": "homologset.agr.MGI:1932134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJ71-1", "uniprot_id": "A0ABK0LJ71_RAT", "id": "A0ABK0LJ71-1", "name": "", "aln": "MMLHLLDHMPEDRPVRDTDSIP--------------LSKGTS-GKNVKAQSRSGRMNREKLNYRPFQLHEDPMVVKELSPKQRDKSRRPRTNMKRSTTTQPDLRTLAVLQ--EPVRQRPPWVSASLRSLVTRHAQVPRRKAHMQRQCPSTAAGSTQSRVHVGRR-PDFS----------GPNDRRSHTAPPTFKDYVMDENPSMEVTSEPSQPT---------------------------HIMTTDSTHAEETSRSPEKMS-----KVEKLEQRSSLECAEKAAELRATIKENVELIRLKKLLYERSASLAATEAQLTRVQEVGISFCLQNQGILDATHDAFLSQVNELKAELSEESKKAVSLRIQLGDVSILQKTLKEFQVRVEDLESERKLLSDSYDRLLENMLESSHQPLESSHQ-PHWNRELMAEQLPQQVCPLLDQVGAELEET-KVLLQVTNQVAQDEQLTFQVTS-----------------ILCQHKQEEENLQSTATIPLFPEELFELAVQPTLLAQTVQRESSEPR--------VQEESSLSQVLNELQVSHAETALELEKTRDMLLLQRKINLCYQEELEATLTKADKENRDHEETMERLTHLLDFKNSRIMQLEGILRSHGLPTSEQLKDVAYGTRQPSLCLESPAAHRGEDEVDMSLLHPSENLFELHIHQAFLTPAALIQAGDAQ-----PTTFCTYSFYDFETHCTPFCTGPQPLYDFTSQYVVQTDYLFLHHLHGTSVRLDLHQAMA-SEHQVLATGWISLDKVLET-VERVHGLATLTGAGGEDLGVLEYWMRLCLPLKSSLQACNKRKKAQAYLSVNVLGGWKAQNDESRSEAWAPQNELRIEITRCCGLRSRWGGRQPSPYVMYRFFTFPDHATTVIPASSDPYFKDQALFPVPVTSDLDEYLRREALSLYVFDDEDPEP-GSFLGRVQVPLLPLAQNKSLKGDFNLTDAGEMSNGSIQVQLDWKSHHLPPESLQMSEAEKQAEEEKEEEREEEEKEEEKEEEEEEEEEKEEEKEEEKEEEKEEEKEEEKEEEEEEEDEGEEEEEKEEEKEEEKEEEKEKEKEKENKDGLEVSFTEEQTPFLPQAQIASTEIPIEAGQYQEKRKPPVIAERKEKERQVTSYSRRKHSKKPGVQGKNRMEYLSCNILNGDI-QQMRYTEWKFSGLKMYEDDGLKVQQKEEEQPSPHSALRQDQPSHSINASSPTDQESSEQASEVSEAHTPDSDDIVVTPQSQTCPKADSEKMCIEIVSLAFCPEADVMADENIRQVYVEYKFCDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPVEHQDRRQFLFAMLQAQNSDEGRLKFTVVSDPLDEEKKECQDIGYAYLELWQIFQSGKDILEQELEIVSPGNQAIQIGRLKVSLQATAALHGIYKEMTEDLFS-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPQ2-1", "uniprot_id": "RPGR1_MOUSE", "id": "Q9EPQ2-1", "name": "X-linked retinitis pigmentosa GTPase regulator-interacting protein 1", "aln": "-MQHLLEYMPEDLPVRDTDSSP--------------LLKGTS-GKNVRAQPHLGRMNQKELNCRRLHLHEEPTLVKEPSPKQRDKNRRRRTNVQRSTTTQPDLRTLAVLQ--EPERRRRPWVSASPSPSAPPRAPVPGRKAHVQRLCPSTAVGSAQPRVHAGRRLPHIA----------GPNDRRSHTAPPAFKDYVADKNTRIEITREPSQLT---------------------------HTMTTDSTHVEEIPRSPEKTS-----KVEKPEQRSSEECTQKAAELRASIKENVELIRLKKLLQERNTSLAATEAQLTRVQEAYEDLLQKNQGILDTAHNAFLSQVNELKAELSEESKKAVSLRTQLGDVSILQITLKEFQVRVEDLEKERKLLSDSYDRLLENMLDSSHQPLDSSHQ-PHWSTELTGKQLPPQVCPLLDQMGTALEET-KVFRQATNKAAQDGKLKFQDTD-----------------ILYQHEQEEESLQSTATVASSPEELCELAAQPTLLPQTDQRESSEPK--------AQDENDLSQVLSELQVSHAETTLELEKTRDMLLLQRKINMCYQEELEATLTKADRENRDHEEKLERLNHLLDFKNSRIKQLEGILRSHGLPTSEQLKDVAYGTLPPSLCLEPLAAHRGDDEVDMSLLHPSENLFELHVHQAFLTPAALTQAGDTQ-----PTTFCTYSFYDFETHCTPLSTGPQPLYDFTSQYVVQADYLLLHYLQGTSVRLDLHQAMA-SEYHVLATGWISLDKVLGT-VERVHGLATLAGAGGEDLGVLEYWMRLCLPLKPSLQACNKRKKAQAYLSVSVLGARKVQSNESRSETWAPQNELRVEITRCCGLRSRRLGRQPSPYVMYRFFTFPDHDTIIIPASSNPYFKDQALFPVLVTSDLDQYLRREALSVYVFDDEDPEP-GSYLGRAQVPLLPLAQNKSIKGDFNLTDSGEKSNGSIKVQLDWKSHYLAPEGFQMSEAEKPEGEEKEEEGGEEEVKEEEVEEEEEEEEEEEEVKEEKEEEEEEEREEEEEKEEEKE---EEEEEDEKEEEEEEEEEEEEEEEDENKDVLEASFTEEWVPFFSQDQIASTEIPIEAGQYPEKRKPPVIAEKKEREHQVASYSRRKHSKKPGVQDKNRMEYLSCNILNGNT-QQMHYTEWKFSGLKKAEDGGLKAQDKREEPPSPRSALRQEHPSHPRNAFSLADQESCEQASEVSETQTTDSDDIIVTPQAQTVPKADSEKMCIEIVSLAFCPEADVMSDETIQQVYVEYKFCDLPLSETETPMSLRKPRAGEEIHFHFSKVIDLDPVEHQSRRQFLFAMLHAQDSDEGRFKFTVVSDPLDEEKKECQDIGYAYLELWQIFQSGKDILEQELEIVSPRNQAIQIGRLKVSLQAAAALHGIYKEMTEDLFS-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KN7-1", "uniprot_id": "RPGR1_HUMAN", "id": "Q96KN7-1", "name": "X-linked retinitis pigmentosa GTPase regulator-interacting protein 1", "aln": "-MSHLVDPTSGDLPVRDIDAIP--------------LVLPASKGKNMKTQPPLSRMNREELEDSFFRLREDHMLVKELSWKQQDEIKRLRTTLLRLTAAGRDLRVAEEAAPLSETARRGQKAGWRQRLSMHQRPQMHRLQGHFHCVGPASPR-RAQPRVQVGHRQLHTAGAPVPEKPKRGPRDRLSYTAPPSFKEHATNEN-RGEVASKPSELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPPKSPEKMWP----KDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSS----DSSSQ-PHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTN-----------------ILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPK--------NQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFLTSAALAQAGDTQ-----PTTFCTYSFYDFETHCTPLSVGPQPLYDFTSQYVMETDSLFLHYLQEASARLDIHQAMA-SEHSTLAAGWICFDRVLET-VEKVHGLATLIGAGGEEFGVLEYWMRLRFPIKPSLQACNKRKKAQVYLSTDVLGGRKAQEEEFRSESWEPQNELWIEITKCCGLRSRWLGTQPSPYAVYRFFTFSDHDTAIIPASNNPYFRDQARFPVLVTSDLDHYLRREALSIHVFDDEDLEP-GSYLGRARVPLLPLAKNESIKGDFNLTDPAEKPNGSIQVQLDWKFPYIPPESFLKPEAQTKG--------------------------------------------------------------------------------KDTKDSSKISSEEEKASFPSQDQMASPEVPIEAGQYRSKRKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGKNRMEYLSLNILNGNTPEQVNYTEWKFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLHPVN-----DKESSEQGSEVSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVMSDENIKQVYVEYKFYDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQEQQGRRRFLFDMLNGQDPDQGHLKFTVVSDPLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPIGRLKVSLQAAAVLHAIYKEMTEDLFS-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58ITH0-1", "uniprot_id": "A0AC58ITH0_DANRE", "id": "A0AC58ITH0-1", "name": "", "aln": "-MSLAVDETAGDLPVRDVGLRAGLITLLADTDHDTRSWRRQPQVLKIKDRQRLFRVPREQLEDQCHRLQEENTLLKQHSRTQEQKLRRLSTKLLRLKHGSSASGRDGELE--DTIEELEARVATLESQKGALQSKLNLAKQHILDLGVRTHIRPRTGRGVDGDG-----------------GVRRAAQTAPARCGISSLDDTRGEMDRLLALLR--------------------------STVIESQQGRVAELELTAQSLRETLRDKEREIEGIVKDLRKQQVDGHRLIIKDNVDVIRLQKQLSEKSAALLVIQEKFGGLQEAYENQLEEGQKSLKESQEALLGKVEELSEQLKQEKQRVLTLEGQLSAATFSLQALGELQERVLDLEGERNLLKKSYDSLLESTMSIQNHQGDKHEEKEERKEELREEGWREELQRLKERLEEARSERKTLEQEKEQMRHEIDQVKKEKERDKDMVMFLREKHDCLEREVLQHRQEVTLLQEKLDSVTKEFDMSVEDLSETLLQIKAFRMQQETQGVMRFLKTDVKFEDTSRDLTAVQASYAETVLELQKTRDLLLLQHRLNADLQNEMTTVLEKSESEREENRRRAEEKDKLLKSRGLQISNLQAQLK--ELAYSPRNNKRAIPLQYTWTGLEQDSVRPTVESAIITHLHGGESLLEVHLTGATFTPLGLRLMAQDTGEHQGVATFCTYGFLDFEVLSTSLMSGGQPNYGFTSQYALSAFDLEKLMVQGGFIAVELHQALGGVKFLTRGRARISLMEALQRRGERVKNRTNLIGVDGEVIGILEFWVCLHPQVERTEPQMERVTSRTPVRHTRGSEWAHGEPEEMYDFGVGIPNELEVVLERCVGLSTRWPGLLPDAYLTYRLYDLPPHSTPIIQCCVDPVFEDSASYPLAVTTDVLEYLNVGSLWVYVFDDGDSQTSHTYLAKTPIPLRSLAAGRPIRGDYVLRDPAGSPRGMVRVSLRWKYPFQSPEVPSRQREGAEK-----------------------------------------------------------------------------ERMMPSAEVSQRPIAKPRSQLRPPSGREATDTHQSTPLRKSERHLITSHQSPSIQVSEASSDRQKPPAQPSRSVRRKHRPATLSNQKPTTPPYRSSAMSTQSPDANAVTDFRASVSEPSTPRSQRSCRSDSEQEVEEQDDETEDKTQSDVDVLHSEESRESNGSDVVIIPHPPKPQKKGDRLRVEILSLSFNPSSSIALDQSVHQVYVEYRLLGVPMETTETPMSLRKPTDGEEIHYNFTRVIHVDSVGAAPLRHYLYTMLEGTDPNQGRLKFTVVSEPMKEQE-ECEDVGYAYLDLRELLLTGNDVIEKQINVVSPNEEQEVVGKLKVSVEAAQALTGIYQEYHQTVKRNRRDPPSSTEDEEEEGTKKKEELHVLDFEVDEDSDFY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: . * **** . . . ::: : *: :::*: :*:*: ::*: * .*.:: :* *.: * . . . .. :. : : *. : * * * : :.*: .: *: : : :: :. * :.:. * .: * . ::. * **::*::***:* * *:.::* : :: :**. :.* *. :::*:* :*:** :*.:*.::.::*. ** .:: :* *:* ** *** **:**...** ***. :. . :. : . . ** : :: * ::: .: .: : . : .:. : : :*.** **. ::* . .*.: . .. *: *. :*.*:***.***:****:*:**:::* *:*: : : *:: :..::.. *. :**. :. :* :*:. *: *. * : :. * ** ..: :.. :: ** .*.*:*:*: * :*. .* .: :*****.* ***. .*.: * ** *.*****.:.: * :: :::***:. :. . . . *.: ..* *:*:. :.* *..** :*:**:*: * :: : :: .. . : : :* . *** : : :* ** :* * *..* **:: :. * * :* .. :* *.*.* :*: **:*: .**. :* ::**** * :. ::*.:. :** .** ...::**: * *.. ..* ::*.* ** . .** . . : : . : : . :.: .: .:*: : . : . .* .*:* : . . :.: . : . : : . * . : . :*. :.. : *: ..: ** .... :* *: ..::: :**:**:* *.:.: *:.::******:: .:*:. ****:***** *****::*::**.:*. *::*: **.. :.::*::******:*:.*:: **:::*****:* ::: :*.*::*:::::*** : :*:****::*: .* .**:* : : ", "identical_positions": 282, "similar_positions": 426, "identity": "19.22%" }, { "cls_id": "homologset.agr.MGI:1932136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES30-1", "uniprot_id": "C1QT3_MOUSE", "id": "Q9ES30-1", "name": "Complement C1q tumor necrosis factor-related protein 3", "aln": "MLGRQRIWWHLLPLLFLPFCLCQDEYME------------------------------------------------------------SPQAGGLPPDCSKCCHGDYGFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGVPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYETKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EMD0-1", "uniprot_id": "F7EMD0_RAT", "id": "F7EMD0-1", "name": "Complement C1q tumor necrosis factor-related protein 3", "aln": "MLRRQLVWWHLLALLFLPFCLCQDEYMEVSRRANKAVARIVQSHQQTGRSGSRREKVREQSHAKTGTVDNNTSTDLKSLRPDELPHPESPQAGGLPPDCSKCCHGDYGFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGVPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYETKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXJ4-1", "uniprot_id": "C1QT3_HUMAN", "id": "Q9BXJ4-1", "name": "Complement C1q tumor necrosis factor-related protein 3", "aln": "MLWRQLIYWQLLALFFLPFCLCQDEYME------------------------------------------------------------SPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** ::*:**.*:************* ***:***************.***************************************************************:************************************************************************************ *************************************************", "identical_positions": 235, "similar_positions": 8, "identity": "76.8%" }, { "cls_id": "homologset.agr.MGI:1932137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16473-1", "uniprot_id": "TENXA_HUMAN", "id": "Q16473-1", "name": "Putative tenascin-XA", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDKNGAPHGAPHSDSP---------------------LG---------FSHAAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTN----GQPQALLVDGDQSKILISG-LEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHP------RPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGRARTQKLQ---------------------------FLTVP--------------HSCVH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22105-3", "uniprot_id": "TENX_HUMAN", "id": "P22105-3", "name": "Tenascin-X", "aln": "MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDE------------------------------------------------------------------------------------------------------------TPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTP--PAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATP---EPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLE-PGRKYKMHLYGLHEGRRLGPVSAVGVTED--EAETTQAVPTMTPEPPIK-PRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSP-----TELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK-PRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVT--EEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTN----GQPQALLVDGDQSKILISG-LEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHP------RPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAP--PLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTG-LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A5F8MPH8-1", "uniprot_id": "A0A5F8MPH8_MOUSE", "id": "A0A5F8MPH8-1", "name": "", "aln": "--MAAQCTPSILTILVLLGLARAGPFSPRSNVTLPAPRPPPKPGG---------PSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCTGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKS--CPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRTCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASIRANTAPGHYSYPEVRPPAPPPNPRPRPRWPSRPLPSPETDEKEWHLRPRLPQPPRRPWGNLTTELSRFRGTVQDLEHHLRTHGYPLRANQTYASVARYIHEFLKRHQTAGAPASQPRHPHPTTSPTQNTRKRDSEQGAVGPASDGAHPVTTARHPKPEVLGSAADGSLIVSLDGLRGQFERVVLRWRPLLPAKGPSGELTVDGSERTVRLPNLRPGTTYHVEVHGVRAGQTSKSYAFITTTTTTTTGSLPSGLLEATDEPPPSGPSTTQGAQAPILILEHHPLGELKVLGRDKAGRLSVAWTAQPDSFAHFQLRMQVAEGPWAHEELLPGDVQQALVPPPPPGAPYKLFLHGITPGGKISVPITYQGIMDRAQEQPGKPSVQPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDG-PQAISVEGPQRSTPISGLEPGRKYKFILYGLIGKKRHGPLMAEAKILIQSDPDPGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFVVQYRDKEGQPRVVPVEGPDRSVVISPLDPNRKYRFTLFGIANKKRYGPLTADGTTAAETKEESSEP-----PRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPDVVDQPLSPPEPSTEAPEPPEKPLLRELIVTDTTPNSLSLSWTVSEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKSSDGRPQVMRVGGQEREVIVRDLDPGHKYKMNLYGLHEGHRVGPVSTVGTTDKQPEEKP-----PLEPRLEELTVTGVTPNSVSLSWIVPEGQFDSFVVQYQDRDGQPREVPLTAEQREVTVLDLDPARIYKMNFYGLHGRRRVGPLSVSAMTAP---APATEASKLLPEPRLGELTVTDVTPDSVGLLWTVPEGEFDSFTVQYKDRDGQPHVVSVAADLREVTIPGLEPSRKYKFLLFGVQDGKRRSQVSVEAKTATHDDTSPGAPPRLGELWVTDPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVKGQERTATITALDAGRKYRFLLYGLLGRKRFGPLTAEGITEPTNAADHT------KSRLGEELRVTGVTQNSVDLSWTVSEGQFDSFVVQYKDRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDSKRVGPLSVIAVTDPRETTEAWTEVPTTSTPAAVPRLGELRVEEATPHSLHLSWVVTEGEFNSFEVQYTDRDGQLRVASTEGDQTDITLTGLESNHRYLITLYGFHDGQPVGSAQIEALTVPWEEEEEEEESTEPPTMTPEPRPQLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKLNLYGIHSGQRFGPVSTVGVTAAVEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTDPKEE-------------------------------------------------------------------------------------------------------------PTDASSLKPRLEELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPRTEAPEP---------------------------------------------------------------------------------------------------------TEAPEPTEEPRLGELTVTGSSPDSLSLSWTIPKGDFDSFTVQYKDSDGRPQVIRVRGQEREVIVRDLD-PGRKYKMNLYGLHEGRRVGPVSTIGVTAPEEEALTTQAVPTTTPEPPPKKPHLGELTVTDATPDSLSLSWTVPEEQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSVVGVTAAEEEPPSPEPSTEAPEPTEAPEPTEEPLLGELTVTGSSPDSLILSWTIPKGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTEEEATTTQAEPIVTTEP-PPKKPHLGVLTVTDATPDSLSLSWTVPEAHFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPSTEAPESTEEPLLGELTVTGSSPDSLSLSWTVPQGEFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGMT--EKEALTTQVVPTTTPEPPPKKPHLGELTVTDATSDSLSLSWTVPEGQFEQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRFGPVSTVGVTTAVEEPPSPTEPSIEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTASLTTEPPIEPRLGELAAVEVTSSTVHLSWTVAQGPFDSFLVQYKDTQGQPQMVPVSGDLGEVTVSGLEPARKYKFLLFGLKDGKRHGPVSTEAKTVSDAKLLPRLGELTVTDTTQNSVGLSWTVPEGEFDSFLVQYKNRGGQVQVVPAAADQREVTISSLEPNRKYRFLLFGLIGLKRLGPVSVEGTTAPVEKTPQPRLGELSVTEETSDSMHLSWSVAQGPFDSFLVQYKDRDGQLQTVSLAADQREVTIEGLQPGRKYKFLLYGLTGGKRLGPISALGVTASEVDISAPDHT----EPPHAPGLGTLAVTEATPDSLRLSWAVARGPFDSFVVQYQDTE----NETQALLVDGDQDKVLISG-LEPKTSYKFFLYGLREGTRHGPVSVEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGAFDSFLLRFGVPLLSTLEQNP------RTLQQRELMVPGVRRSAMLRDLRPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSAKVKWVPPTSRVDSFKISYQLADGGEPQSVQVDGRTQTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDKYDVEVESPGAP--PLQASAPGSAVDYPLTDLALDTNYTATVRGLRGPNFTSPASITFTTG-LKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPFPRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQVPTRGT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9P891-1", "uniprot_id": "A0A8M9P891_DANRE", "id": "A0A8M9P891-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKLGTSTQYKMLISLVFLILN---VSFLQGTLSENKNDTIKTIDHTFSHHIPVQVTTPLSTKVKKQTHAASSKMSNSNQTLPFTPKPVVDDIQKSVPLFQDTLSAKDNSTSESRLNAHNVHKPLTRLSNTKIRNQTQSTSSISSSISQTLPSSTEPAVDGVQKPVLALRGKLNEKKHSTVQSTAHLGSLDIPKLVTTKLINKMKNQTRPTLAKPSSVNQTLPSVKKIVADQSTITEKKNSTANLPTQIISVPKTDKKTKN----------------------------------------------------------HTQSTFSITSNINQHQDIVEKHPPSLQDPHSQKKNSTMKSPTQTIKVVTTSLNSKKKDQTQSTSLTYSKVNQSLSSSTKPNIHTSQKPMQGVQNKISEKTNSTNKSTVSNVNVQKPATKLNTKLKVQTQYTSSTKTQVNQILTTSTRPEVDSIQNPVQSVQNTISGKKNSTTKSTVNTINVQKP-------VTSLLKTKLKEQTQSSSSTSQLNQTLTTSQK------------------------------PGVDSIHKPVQSLQITFGGKTNSTTKSIVNIVDVQKPATKLNTKMKVQTQSTSLTTTQVNLTLPSSTMPEVDSVQKPVQSVQNTISGKKNSTTKSTVNTSNVQKPVTS--------------------------------------------------------------------------------------------------------------------------------------------------LLKTKLKEQTQSTPSTSQVKQTLTTSSKPEVDTTQKPVQSVQNTIGDKKNSTTESIVNTINVQNPATRLNTKLKDQTQSTSSTTSKVNHTLPSSTMPDVDTVKKP------------------------------------------------------------------------------------------------------------------IQSLQNKIGDKKNSTTKSTVNTINIQKPVTSLLKTKLKEQTQSTPSTSQVNQTLTTSTKPEVNSIQNPVQSVQNTVSDKNNSTTKSTVNTIKVQKPVTSLLKTKLKEKTQSTPSTSQVNQTHTTSTKPEVESIQN----PVQSVQDTISGKKNSTTKSTVNTIN----------------------------VQKPVTSLLKTKLKEQTQS------------------------------TPSTSQVNQTLTSSIKPEVDSIQKPVQSAKNTIGDQTNSTTKSTVNIINVKKPVTTLLKNKQKERTQSISSTTSQVNQTLPASTKSDVDSIQKPVQSVQTTINDKKNSTTKSTDN----------HIIVQKPVGTLLKNKMRIQALSNSTKNSIIDQTSLSAKPAVDVVQKS----VSPSPTTFGEKRNTTTKLVSHNINVNASKPENTKVQTQSVSSKPTHINQTLLSTPKPAVDVKTPGSALQDISGTKKNSTSKLTAQTIRNNVPTLTTLLNIKLKNQTHPS-------FSTISHVNQTVPFSTKFVDEVTHRMKKNSTVKARLQTININASKPVTTSLHTKTKNQTQSTSLKISKANQTSPSTTKPVEGEISLGKKKNFTVKSASQS-------------IDVHASKPITTPPNTKTKNQTKPSSSKNNNNDQAVTSTSPVMDGTQNLDIDKLAESSPIKIVITEGCVQRKSQGDVGNITKIRETELSLNPGSPLVMTHRINLVQGTCNG--------------------GCETDMAALRERIELLEKEMSAIKQMCVPCSGEQCPKNCSGQGKCEEGKCVCFQGFSGPDCSSKACPSNCNKKGK---CVKGKCVCQTGFTGIGCSKAIDER------ITVTVETVTMKMSSAMPDTKTVKTRPDKAILVKETVTKVPKKHTTAKPTVKPSPTASTDKVLSHTTGKDNIKIVGQQSESMKLQEQTKGKTTVIKMGSDNQAQTDLSDKSHNAKD-------------------------------EPAYQNVTQRSVKKSNGTSKILHNLFKGSMNVTRSKTKITTRTAGDQGEESKTNAVSAEKDEKLFHGNVTTVQAEKKSDKPEIDASVESKAHMKHFSKTSSRLSVIGSVEVHNITSTG-FIMSWEAHRDKFKNFTVTRREIKAGNEDSEKIHEAIENVTDAERLGSNRTLTKILSSKSEGNAMKKFSQILAGTTRSYHFKGLQPQTQYAISLFGSGPGMRSKIHR---ITLSTGPEPPTDLVFSNITETSFSLSWAKPKSIVAEFKVKYINTVTGESGSMSVDSQLSHVLLSKLTAGTTYDITVSSVLDKLESEPVIASITTVPDSPTELKVVNITDTKALLVWKPSKAKVDSYILSYGTTKSPNVTITVTLSGSSVEHQLRALHRSSLYMVKMTSQVNRLQSSSVSTSFTTGSGVKLQVVTPDEVTFHSAVISWKAPRVAFKSYRLTYQLS-EEVKELILNPSVTHYELTGLAAFSNYTVKIDGERDGQYISFVSSDFTTAQLPHPYPTDCSEVQINGMKESGEAEIYPEGKNGEPVRVYCDMETDGGAWTVFQRRMDGSTDFFRSWRDYSKGFGLLSGEFWLGNDVLHTLTSLKAMSLRIDLRSGNDTAFAQYINFNISSEANHYAIDLSGYSGTAGDSMKYHKGRPFSTKDKDPDTLSIHCAKAYMGGWWYKNCYKANLNGLYASYSDNKGVVWIDWKGKDASLPFTEMKLRPSNFSQTTSTTPTAQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : . : : : . : : . * : ** :... : . .: .*. :. : .: :: .: ...* *.. :*..: :.: . . *.:.... *. ::.:::*: .: . : * *::.. : ** ..: : . ::.*. :* ::.*:. * *:::*:* ::. : ***. *.* ** **:* *** .:.* * * . .**:.* : **. *:.**.: *. : *** : : ", "identical_positions": 50, "similar_positions": 111, "identity": "1.08%" }, { "cls_id": "homologset.agr.MGI:1932139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIJ5-1", "uniprot_id": "OGA_RAT", "id": "Q8VIJ5-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFGVP--------------------------------------HQYSSRQVAHSG------------------------------------AKTSVVDGTPLVAAPSLNATTVVTT-VYQEPIMS-----QGAALSGEPSALTKEEE----KKQPDEEPMDMVVEKQEESE-HKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMS---------MQEDCINDIAPMQTDEQAN-----------KEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLG------------------CRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDG---------VGLPFQSQ-PDLIGDKLVGGLLSLSLDYCFVLEDEDG-ICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQQ9-1", "uniprot_id": "OGA_MOUSE", "id": "Q9EQQ9-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQAALEERESERNANPAAASGASLEQSVAPAPGEDNPSGAGAAAVVGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFGVP--------------------------------------HQYSSRQVAHSG------------------------------------AKTSVVDGTPLVAAPSLNATTVVTT-VYQEPIMS-----QGAALSGEPSVLTKEEE----KKQPDEEPMDMVVEKQEEAE-HKNDNQILTEIVEAKMAEELRPMDTDKESMAESKSPEMS---------MQEDCIPDVAPMQTDEQTQ-----------KEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLG------------------CRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDG---------VGFPFQSQ-PDLIGDKLVGGLLSLSLDYCFVLEDEDG-ICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60502-1", "uniprot_id": "OGA_HUMAN", "id": "O60502-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFGVP--------------------------------------HQYSSRQVAHSG------------------------------------AKASVVDGTPLVAAPSLNATTVVTT-VYQEPIMS-----QGAALSGEPTTLTKEEE----KKQPDEEPMDMVVEKQEETD-HKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMS---------MQEDCISDIAPMQTDEQTN-----------KEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLG------------------CRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDG---------VGLPFQSQ-PDLIGDKLVGGLLSLSLDYCFVLEDEDG-ICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RWC3-1", "uniprot_id": "A0A2R8RWC3_DANRE", "id": "A0A2R8RWC3-1", "name": "Protein O-GlcNAcase", "aln": "MVQKDKIIESSQPEVEVIPVPVEAVADTQCPVDEPTIEIER-------------TGRRKFITGVVEGFYGRPWTMEQRKELFRRQQKWGLN---TYLYAPKDDYKHRMFWREMYSVEEAEQLTTLISAAKEYGIEFIYAISPGLDITFSNQKEVSTLKRKLDQVTHFGCKSFALLFDDIDHNMCPADKEVFSSFAHAQVSVTNEIFQYLGEPEIFLFCPTEYCGTFCYPNVSQSPYLRTIGEKLLPGIEVLWTGPKVVSKDITVESIEEVTKILRRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFESNFVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EELETDILYSPQIALKLALTEWLSEFGVP--------------------------------------HQYNSRQVPHSG------------------------------------TKSTTMD-VPTLAASTLVTSTTVTT-VFQQPIMS-----PVLPLSDEPHVLGKEEEEEVEKKESDEEPMEMVVEKHDEVEDTKNVNQILTEIVKAKMTEDLKPMDTDKESLTESKSPEMS---------IQEDSGSDIAPMQTDDQLN-----------KEVFVPGPNEKPLFITEALTLEDLTLLAELFYLPYEHGPKSVQMLKEFNWLRANSNYVSVNSKA--------KDPEKVTEWQSRAENFEEMCCSVMQMFTRLSNSANRTILYDLYPYIWDIKSIISMVKSFVQWLDGRILGTSFYCYWTDSARWCRSQSSAQFLSGDQEPWAFRGGLAGEFQRLLPIDGANDLFYQPPPSMPTSKIYTIRPYFAKDESAIYKICKEMFTESC--------EGISFSDESPDLIGDRLVGGFLTLSPDYGFVLEDEEG-VCGYAMGTVDVKPFVKKCKLSWIPFMQEKYIK-----PDAEKDLSEAEKMMLSFHEEE-----DGLPESFLRNFPSLIKVDIHAKVT--DPSVAKSMMGCLLSSLKANGSHGAFCEVRQIDKRMLDFYSKLGCFEVAKMEGFPKDIIIMGRSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDC9-1", "uniprot_id": "Q9VDC9_DROME", "id": "Q9VDC9-1", "name": "protein O-GlcNAcase", "aln": "-----------------MADEAGSQAD----------------------------GKRQFICGVIEGFYGRPWTTEQRKDLFRKLKSMGMGSSPSYMYAPKDDYKHRAYWRELYTVEEADHLSSLIAAAKEAGITFYYALSPGLDMTYSSPKEIATLKRKLDQVAQFGCEAYALLFDDIESELSKADKEVFQTFANAHVSVTNEIYTHLGSP-RFLFCPTQYCASRAVPTVQESEYLNTLGSKLNNEIDILWTGDKVISKNISLESIQEITEVLRRPPCIWDNLHANDYDQKRIFMGPYSGRSPELIPHLRGVMTNPNCEFYGNFVAIHSLAFWSRCSLD---------SKVNSSLSADIKLETENDDDLPAEFLSKNVYHPRLALKNAITEWLPEFFMKKEAWGPITKPQPQVQMVMPIIPIIPSINTCMSLTTTTTTSTSSRTVPPTVNTTQLQALADVCVVTSSLTPISNPVMNSLVSPTKVITNDDIINPIPTTAASNIELPKKIPISVVPVPIMETKSVEASVELALDNAVFDDNEIEPNSDSVKERLELEVNLEGKQEPVANLSVDTMLDDDSLSPLSGVVNEPMECSSSITSQVSPREEEAIKVVADDVLMESVNDVHSMHVESGTSSPISNAEMREETEAQSDRTNDNNTIEGEGITVDDLVLLCDLFYLPFEHGSRGHKLLVEFNWLKGNANVILQDRSAGGGGDAIKSDKPEVSEWHQRREQFDQLCSAVVELLIKIANCPNKEICHELYSYMWDISGALSLLNCYVKWLALGHFPQNTSSYTEGSYTWFSKGWKEAFMSGDQEPWVFRGGLIADLQRLMPVDSGNDLFVYKLPEQPTANYYLLRPYCNSDEQQVNDLCTRLYLQWRGELDGGRHIPFPLPANVPNIVADGLIGGYLTLSPQLCIVAYDESNRIIGYSCAALDVNIFRRNLELCWYTELREKYSRDICPLEGGEEVVQLVTSLVESYHDSSGNGALDQCPVEVSGSFPAVLISGTLREAEERDSGITKRMLTVLLAALRANGCFGAHVRVPQQDVAQVNFYSRIGFVDVYREEAT--KCIYMGRRF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * *:*: **:********. ****:***: :. :. :*:********** :***:*:****::* :**:**:* * * **:*****:*:*. **::*********::***.::*******: ::. ******.:**:*:**:****: :**.* ******:**.: . *.*.:* **.*:*.** *::**** **:**:*.:***:*::::::*.* ****:*********:*:***.***.****:*:**:******* .*:****:** * :..:: .. :*::* :****.*..* :: :. :* *::*** *:**** ** : . .** *. : :: :: * **..: .. :. * ***. *: : .: .:* .. :. ::: :* ::* . : :* : : :: :. ..*::.. **. . : :. *: .*:.:. . .* .*:: * :*::** **.:*****:***.:. ::* **:**:.*:. : : .. .* :: **:.* :*:::* *: :: :::*..*: * :::*.*:***.. :*:::.:*:** . . *: ******.***** .::***:*:*..**** * **:: * :*** .** : .:* .:: : :.: : *:::.* *:** *:** : :* **.. : **: .::**. * :: ::.* . ::*** : ..:: :. . .:: *:*:.. : * . .**::: . :. *..::* *: **::*:***. **. .* * ::***::* .:: : *. . : :** :", "identical_positions": 327, "similar_positions": 317, "identity": "30.39%" }, { "cls_id": "homologset.agr.MGI:1932286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YE3-1", "uniprot_id": "EGLN1_MOUSE", "id": "Q91YE3-1", "name": "Egl nine homolog 1", "aln": "MASDSGGPGVLSASERDRQYCELCGKMENLLRCGRCRSSFYCCKEHQRQDWKKHKLVCQGGE-------APRAQPAPAQPRVAPPPGGAPGAARAGGAAR---RGDS-AAASRVPGPEDAAQARS-------GPG-----PAEPGSEDPPLSRSPGPERASLCPAGGGPGEALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGRETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDQITWIEGKEPGCETIGLLMSSMDDLIRHCSGKLGNYRINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLT--GEKGVRVELK--PNSVSKDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59722-1", "uniprot_id": "EGLN1_RAT", "id": "P59722-1", "name": "Egl nine homolog 1", "aln": "----------------------------------------------------------------------PRAQPAPAQPRVAPPPGGAPGAARAGGAAR---RGDSSTAASRVPGPEDATQAGS-------GPG-----PAEPSSEDPPPSRSPGPERASLCPAGGGPGEALSPSGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGRETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCSGKLGNYRINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLT--GEKGVRVELK--PNSVSKDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZT9-1", "uniprot_id": "EGLN1_HUMAN", "id": "Q9GZT9-1", "name": "Egl nine homolog 1", "aln": "MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLT--GEKGVRVELNKPSDSVGKDVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6P6J7-1", "uniprot_id": "F6P6J7_DANRE", "id": "F6P6J7-1", "name": "hypoxia-inducible factor-proline dioxygenase", "aln": "---MEGNSRESERLERERQFCELCGKMENLMKCGRCRSSFYCSKEHQRQDWKKHKRVC----------------------------------------------KEADKQQQPVGEEEEEQPSDT---------------SKQSSTSQSNSTLTSQDEKMPDFIKSATGSDTKPTPDSSKPNGQTR-SPPQKLATDYIVPCMNKHGICVVDNFLGNEVGRSILEDVRALYLTGGFTDGQLVSQRSDSSKDIRGDKITWVEGKEPGCERIAFLMSRMDDLIRHCNGKLGNYRINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDATEHGGLLRIFPEGTAQFADIEPKFDRLLLFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKEKYSTSSGERGVKVELNK-PSEPS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F518-1", "uniprot_id": "E7F518_DANRE", "id": "E7F518-1", "name": "hypoxia-inducible factor-proline dioxygenase", "aln": "---MEKCPTVLD-PDGDKQYCELCGKMENLLKCGRCRISFYCSKEHQKEHWKKHKLTC----------------------------------------------READKHN-TVPQTQQQHP--------------------KTAHPEKNNLICS------------SEADLKAKPHT------------QKLATDYIIPCMNKHGICVVDNFLGEDMGLSILEDVKALHQTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCEKICFLMSRMDDLVRNCNGKLGNYIINGRTKAMVACYPGKGTGYVRHVDNPNGDGRCVTCIYYLNKNWDAKEHGGMLRIFPEGKAQFADIEPKFDRLLLFWSDRRNPHEVQPAYSTRYAITVWYFDADERARAKEKYLTGAGEKGVKVELNK-PSEPS----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : :.. : .: . *** :**:************:***.: * .* ::*:**: ** *********:**********:***:******** * :*** ****:*:*.****.* **************:**************************:***. **:*******.**************:***************:******************* ** * **:**:***: ... . ", "identical_positions": 182, "similar_positions": 43, "identity": "42.52%" }, { "cls_id": "homologset.agr.MGI:1932287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYU4-1", "uniprot_id": "EGLN2_RAT", "id": "Q6AYU4-1", "name": "Prolyl hydroxylase EGLN2", "aln": "MDSPCQPQALN----QALPQLPGSVS-----------ESLEP--SRARMGVESYLPCP-----------LLPSYHRSGASGEASAG----NGTPRTTATATTTTAS--PLREGFGGQ----------DGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRKWAKDGGDAPSPSKRPWARQENQEAKGESGVGCDSGGG----SSNSTTHSSGEASSRLR-EEAQPSAPERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAG--RLGNYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPATPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YE2-1", "uniprot_id": "EGLN2_MOUSE", "id": "Q91YE2-1", "name": "Prolyl hydroxylase EGLN2", "aln": "MDSPCQPQALN----QALPQLPGSVS-----------ESLES--SRARMGVESYLPCP-----------LLPAYHRPGASGEASAG----NGTPRTTATATTTTAS--PLREGFGGQ----------DGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRKWAKDGGDAPSPSKRPWARQENQEAKGESGMGCDSGASNSSSSSSNTTSSSGEASARLR-EEVQPSAPERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAG--RLGNYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPTTPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KS0-1", "uniprot_id": "EGLN2_HUMAN", "id": "Q96KS0-1", "name": "Prolyl hydroxylase EGLN2", "aln": "MDSPCQPQPLS----QALPQLPGSSS-----------EPLEPEPGRARMGVESYLPCP-----------LLPSYHCPGVPSEASAG----SGTPR--ATATSTTAS--PLRDGFGGQ----------DGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSG------------SGEASAGLM-EEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAG--RLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Y6-1", "uniprot_id": "A0ACD6B6Y6_DANRE", "id": "A0ACD6B6Y6-1", "name": "hypoxia-inducible factor-proline dioxygenase", "aln": "MERLGNTDLINAHGRESISSTPDRVSNTMGLNATTAGELLAGHMSRSGSGITLLKDSKSGLSLCNGGGVLSPSPKADRSYDEAQSKRLHLNGLVETPNGALTSHGDNRPMKRPIGELRFRQIQHQRRKDEENRDFGTNGCSANGS-GCGCSSETDPIHECKRRKVEIDSKTDSSKSMRTVPPLAANHQHKNCSASHPNGVYHNGHKVALNHVAPGQAEVRTAPPLVATCSPEHMAQQYIVPCMKFYGICVKDTFLGERLGSRVVEEVQTLNRSGKFRGGQLVIQKNIPSKNIRGDQIAWVEGNEPGCENIGTLMAHIDEAIMRSAANGQLGDCVINGRTQAMVACYPGSGTGYVRHVDNPNGDGRCITCIYYLNKNWDVKVHGGLLQIYPEGRNVVANIEPVFDRLLIFWSDRRNPHEVMPAFATRYAITVWYFDAKERAEAKEKYRLASGQKGVQVPVTQSSKT-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :.: :. :::.. *. * * * .*: *: . * *: : .**.: .* . * :: .. *:: :* .. * : ::*.:* : * : .. *. :** *. .* * *. . :. . : . . . .*:*. . ..:**::* :******::*******.*** **.**: **::*: .*::*.**** *: **.:.***********:****..**:****:* .* :.*. :**. ******:********.* *********:*************:*************:**** *******:***************** **:***************** *::**:************:*.... ", "identical_positions": 202, "similar_positions": 106, "identity": "43.35%" }, { "cls_id": "homologset.agr.MGI:1932288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62630-1", "uniprot_id": "EGLN3_RAT", "id": "Q62630-1", "name": "Prolyl hydroxylase EGLN3", "aln": "MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHYNGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAINFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGVLRIFPEGKSFVADVEPIFDRLLFSWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALAKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91UZ4-1", "uniprot_id": "EGLN3_MOUSE", "id": "Q91UZ4-1", "name": "Prolyl hydroxylase EGLN3", "aln": "MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHYNGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAINFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGVLRIFPEGKSFVADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALAKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6Z9-1", "uniprot_id": "EGLN3_HUMAN", "id": "Q9H6Z9-1", "name": "Prolyl hydroxylase EGLN3", "aln": "MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************** .**************************************.***********************************************************************:**********:************ ************************************************::*", "identical_positions": 231, "similar_positions": 6, "identity": "96.65%" }, { "cls_id": "homologset.agr.MGI:1932289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40890-1", "uniprot_id": "VTH2_YEAST", "id": "P40890-1", "name": "VPS10 homolog 2", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLT---WTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDK-SKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSS------DKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHP--CPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLG--------LCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTSRTDLLGASNIPDALPARS--ASHESDLAAARSEDK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40438-1", "uniprot_id": "VTH1_YEAST", "id": "P40438-1", "name": "VPS10 homolog 1", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLT---WTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDK-SKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSS------DKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHP--CPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLG--------LCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTLRTDLLGASNIPDALPARS--ASHESDLAAARSEDK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53751-1", "uniprot_id": "YN94_YEAST", "id": "P53751-1", "name": "Uncharacterized membrane glycoprotein YNR065C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIP--YDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKG-TFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCGESDYECSFEFVRDANGLCIPDYNLIAFSNICDK-SKDKSVLVEPLQLIKGDECKTPMKIEPVDIPCDEIPEEGSS------DREIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTNGEKIVEVVFNPYFNSSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKKSSETRSLVSSIDFFQGDNKIIFENIIGYLSTGGYIIVAVPHEDNELRAYVTIDGTEFAEAKFPYGQDVSKQEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNREKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDKLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGKKRADFKYSPLGSRTGCLFGHQTEFLRKTDEKCFIGNIPLSEFSRNVKNCSCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHP--CPGKEKAFREKYSINTGAYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLG--------LCISLITKSAFQRTKAGVARFSSKLRARFGNRKGPTYSSLLQGQFSDESD----GLHEDANDLSSFTSQDSNFEIEQEDAYRPEQEHTSQIDQPATSNIPDALPARS--AIHKPDSTAVRNEDE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32319-1", "uniprot_id": "VPS10_YEAST", "id": "P32319-1", "name": "Vacuolar protein sorting/targeting protein VPS10", "aln": "MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDDSNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINFYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKSKGVTKISVDNGLT---WTMLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIP--YNADEDDDPQSEFYYSLDQGKTWTEYQL---ETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTN-------FIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQ--LFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCDK-TKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTN------DKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYYNSSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLGSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHA--CPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVKSG--------FYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTTDVPDTLPEGNEENIDRPDSTAPSNENQ-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25657-1", "uniprot_id": "YCY9_YEAST", "id": "P25657-1", "name": "Uncharacterized protein YCR099C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSIFLLHFDYKTCEEEDFEDWNLADGKCLNGAKYMYKRRKQDARCLVKRTFKDMI--LHEIPCDSCTESDYECSSEFVRDAKGDCIPDYDQIALSDICDK-ANGETVSLEPLQLIKGDKCKKPMEIEAMNIPCEKILRESSN------GKKIATIENKFDFEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D3ZW09-1", "uniprot_id": "D3ZW09_RAT", "id": "D3ZW09-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRGTPSAPKRPGLTAPDRSSQVLLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRWGPSVQVTRLL---PAGRTESSNRQDPQTRESEPGVPGLRPGSASGPSTDGAPALGKGRRVRAAPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRK-IILVSSSLGDREQSLFLSTDEGTTFQKYPVPFLVETLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQEQVTKDHVFWAVSGVDDDPNLVHMEARDLSGGYRYYTCLIHNCSAQPHTAPFPGPTDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALPKLFCPQDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQP-------------------PDCHLHLHLRWADNPYVSGTVH--TKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKTLKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFR----------PSFPRPCVEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTVNKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGINQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLQFSRDLDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPPPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRVLVELRDTDAGPQR-----------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQEMTSPVSHSEDAQSAMQG--------------NHSGVVLSINSREMHSYLVG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPR5-1", "uniprot_id": "SORC2_MOUSE", "id": "Q9EPR5-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRGPPSAPKRPGPTAPDRSFQALLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRQGPGVQITRLL---PAGRTESGDRKDPQARESEPSVPGLGPGSASGPSTDGAPAPGKGRRARAVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRK-IILVSSSLGDREQSLFLSTDEGATFQKYPVPFLVEMLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALP-----KDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQP-------------------PDCYLHLHLRWADNPYVSGTVH--TKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFR----------PSFPRQCGEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSRELDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQR-----------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQEMTSPVSHSEDAQSTMQG--------------NHSGVVLSINSREMHSYLVG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PQ0-1", "uniprot_id": "SORC2_HUMAN", "id": "Q96PQ0-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRGPSRASKGPGPTARAPSPGAPPPPRSPRSRPLLLLLLLLG-ACGAAGRSPEPGRLGPHAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWERAAPLAGVAS--RAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRK-VILVSSSLSDRDQSLFLSADEGATFQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVTKDHVFWSVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFFKATSANQTKYYVSYRRNEFVLMKLPKYALP-----KDLQIISTDESQVFVAVQEWYQMDTYNLYQSDPRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKGRDWDYLRPPSMDMNGKPTNCKP-------------------PDCHLHLHLRWADNPYVSGTVH--TKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGLTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFR----------PSFSRQCGEEDYSSWELSNLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFLCDYGFERSSSSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQLQCPLTPPRGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVLDQFQVMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLADLYVLLPPPRPTRKRSLSSDKRLAAIQQVLNAQKISFLLRGGVRVLVALRDTGTGAEQ-----------------------LGGGGGYWAVVVLFVIGLFAAGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQEMTSPVSHSEDVQGAVQG--------------NHSGVVLSINSREMHSYLVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G5D7-1", "uniprot_id": "A0AC58G5D7_DANRE", "id": "A0AC58G5D7-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTLIMAVFAHLYPAVFFACAWMALLGPISCHSSGIIKQRSERDR-------------------ELDSRGGHVTGTDEALISAYSRGDYSG--DPGGAAVGVPRVRRAS--------TPEKVSLLSSSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADSNKVLESSLWRSSDYGSTYTKLNLMPGTTIIVTNFYICPTNKKK-VILVSSSINERDQMLFISTDEGASFQRQPVSFTVDSLLFHPSEEDKLLAYSKEAKLYISTDLGHKWTLLQERVTKDRVFWAVTGVDVDPDLVHMEMQDISGGYLYVTCLIQNCSDKMVTAQFLGKIDHNSLSVQDEYIFVKVTTGNRTKYYVSYRRNEFVQMRFPKYSLP-----KDVQIVSTDENQVFLALQEWYQTDTYNLYQSDPQGVYYSIVLENVRSTKQPEENVLIDILEVRGVKGVFLANQKVDGKVMTLITYNKGRDWEALAPPATDMNGKPVSCKQ-------------------PDCHLHLHLRWADNPYVSGTVH--TKDSAPGLIMGAGNLGSQLVEYKEEMYITADCGKTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSIDEGRTWSIHNFTSTSVFVDGLLSEPGDETLVMTVFGHISYRSDWELVKVDFR----------QSFPRQCTEADYDSWKLTDLQGEKCIMGQERVYRRRKETSFCIKGKSYTSALTAKPCPCSEKDFTCDYGFERAPSLRLEGDRCYPDFWHNPDAPPENCHLGHSYKSSTGYRKVIANVCEGGLNKEQSAKQHSCPLLPPKGLQLGIKGQMLAVAPGDDITFIVHQEQGDTSSTRYQVDLMDGVRAIYENLTVTDEPIQHRYEKPGVYRVNVKAENSAGHDQAMLYIQVTAPLQDVHLEVVPIAGRNQDVNLTAIVLPTEANLTVFYWWIGDNMQPKLTLENSLITRFSEEGEVPVTVQASNGRSMVQDSKTVIVYDHFQIIPLSFSRNLDHFNPNIPEWRRDVGEVVTKIIAKLTGVPQEHLVTMLKPGLPTSADLYVLPQETTP-VKRSVFVDKRVPTIKQVLSENNVSFIVRGGLRVLVTLADLDSGPITSDVSVSTTETATQLTSSTQGSGLAAAGPGVWAVAVFLLISLISAAAFILFKFKRKNYKNHGWLLRPEESSLTRPWLRFRKLPGRNVYAQMHNEKEQEMTSPVNHSEDTQNIIQGEEFIDDDLDSQTLGNHSGVVLSINSRELHSYLTS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* * :.* . . : : : .:.* : : * : * . : . *: : .: . :. * : . :: . . . . :* ::. * ", "identical_positions": 11, "similar_positions": 36, "identity": "0.68%" }, { "cls_id": "homologset.agr.MGI:1932339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7T6-1", "uniprot_id": "G3V7T6_RAT", "id": "G3V7T6-1", "name": "Splicing factor 3B subunit 1", "aln": "MAKIAKTHEDIEAQIREIQGKKAALDEA----QGVG-LDSTGYYDQEIYGGSDS----RFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAG-ELKVVNGAAASQ---PPSK---RKR-RWDQTADQTPG-ATPKKLSSWDQA----ETPGHTP-----SLRWDETPGRAKGSETPGATP--GSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDR-----GGDSIGETPTPGASKRKSRWDETP-----------ASQMGG--------------STPVLTPG-KTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGG-MTGFHMQTEDRTMKSVNDQPSG-NLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75533-1", "uniprot_id": "SF3B1_HUMAN", "id": "O75533-1", "name": "Splicing factor 3B subunit 1", "aln": "MAKIAKTHEDIEAQIREIQGKKAALDEA----QGVG-LDSTGYYDQEIYGGSDS----RFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAG-ELKVVNGAAASQ---PPSK---RKR-RWDQTADQTPG-ATPKKLSSWDQA----ETPGHTP-----SLRWDETPGRAKGSETPGATP--GSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDR-----GGDSIGETPTPGASKRKSRWDETP-----------ASQMGG--------------STPVLTPG-KTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGG-MTGFHMQTEDRTMKSVNDQPSG-NLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99NB9-1", "uniprot_id": "SF3B1_MOUSE", "id": "Q99NB9-1", "name": "Splicing factor 3B subunit 1", "aln": "MAKIAKTHEDIEAQIREIQGKKAALDEA----QGVG-LDSTGYYDQEIYGGSDS----RFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAG-ELKVVNGAAASQ---PPSK---RKR-RWDQTADQTPG-ATPKKLSSWDQA----ETPGHTP-----SLRWDETPGRAKGSETPGATP--GSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDR-----GGDSIGETPTPGASKRKSRWDETP-----------ASQMGG--------------STPVLTPG-KTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGG-MTGFHMQTEDRTMKSVNDQPSG-NLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYDLDYIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QQZ1-1", "uniprot_id": "F1QQZ1_DANRE", "id": "F1QQZ1-1", "name": "Splicing factor 3B subunit 1", "aln": "MAQIAKTHDDIEAQILEIQGKKAALVVEGGD-QGVG-LDSTGYYDQEIYGGSDS----RFDGYLTSIAANEQEDDDDE-DSSTSLLVQKKPGYHAPVAILNSIPQSDEQYDPFAEHRPQKISDREDEYKKRRQKMIISPERHDPFADGGKTPDPKVQVRTYMDVMKEQQLSKEEREIRLQMVEKAKAG-ELKAVNGSAASQ---AAAK---RKR-RWDQTADQTPSNSTPKKVSSWDQADGGSETPGHTPGHTPSNSRWDETPGRPKGSETPGATP--STRMWEPTPSHTPAGAATPGR-DTPGHATPGHGGATSSVRKNRWDETPKTERETPGHGSGWAETPRTDR-----GDESVGETPTPGASKRKSRWDETP-----------ASQMGS--------------STPLLTPG-KTPLGTPAMNMATPTPGHLMSMTPEQLQAWRWEREIDERNRPLTDEELDAMFPEGYKVLPPPAGYVPIRTPARKLAATPTPIGG-MTGFHMQTEDRSMKQVNDQPSG-NLPFLKPDDIQYFDKLLVEVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPLIFNDEKNSYVRYELEYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPR5-1", "uniprot_id": "Q9VPR5_DROME", "id": "Q9VPR5-1", "name": "Splicing factor 3B subunit 1", "aln": "MENIPRTHEDIEAQISVIQEKKTELAKTTAAAAGVGLLDSGGFFDSDLYDDDAAKGKGRYEGYNTSIAANDAEEVDEDEDDGFPVP-QKRTTYTAPASVLKDVTQGKEDVDPMADRRRPTIADREDEYRQKRRHIIISPERADPFADGGKTPD--VGSRTYTDIMREQMLKGEESELRRRILEKTKEGTLVKTVTSSSTSNGDLPAPKDGGRKRGRWDQTVSDSFIPAKMATPSSAATP----TWEDKTPG----DHRWDETPG-HKGSETPGATPGLGTRIWDATPAHAVT----------PGHETPGH---EKSARRNRWDETPKTERETPGH-SGWAETPKPDRTGSGGGAESISIESTPGASKRRSRWDETPSNATPAITPTNASAMTPNMTPSMTPHVTPGHATPMLTPGGSTPIGVKAMAMATPSAGALAAMTPEQLQAYRWEKEIDERNRPYTDEELDQIFPPGYKILPPPAGYVPLRTPGRKLMATPTPIAGTPAGFFIQVEDKNAKFMDNQPKGQNLPFMKPEDAQYFDKLLVDVNEDSLSPEELKERKIMKLLLTIKNGSPPMRKSALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRVLYKLDDLVRPYVHKILVVIEPLLIDEDHYARIEGREIISNLAKAAGLATMISTMRPDIDNIDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLKALVEIIEHGLVDEQQKVRTITALAIAALAEAATPYGIESFDSVLKPLWKGIRTHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKEEILPHFFKFFWNHRMALDRRNYRQLVDTTVEIANKVGASEIINRVVDDLKDENEQYRKMVMETVEKIMGNLGAADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTIVNQLGKRVKPYLPQICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGPEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAESCRPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVCPLLEDALMDRDLVHRQTACSAIKHMSLGVYGFGCEDALTHLLNYVWPNIFETSPHLVQAFMDSVDGLRVSLGPIKILQYTLQGLFHPARKVRDVYWKIYNSLYIGGQDALIAGYPRITNDPKNQYERYELDYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49955-1", "uniprot_id": "SF3B1_YEAST", "id": "P49955-1", "name": "U2 snRNP component HSH155", "aln": "------------------------------------------------------------MSHPIQFVNANNSDKSHQLGGQYSIPQDLRENLQKEAARIGEN--EKDVLQEKMETR--TVQNREDSYHKRRFDMKFEPD-------------------------------SDTQTVTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SENTQDAVVP--RKRKSRWDVKG-----------------------------------------------------------------------YE--------------------------PPDESSTAVK------------------------ENSDSALVNVEGIH-DLMFFKPSDHKYFADVISKKPIDELNKDEKKERTLSMLLLKIKNGNTASRRTSMRILTDKAVTFGPEMIFNRLLPILLDRSLEDQERHLMIKTIDRVLYQLGDLTKPYVHKILVVAAPLLIDEDPMVRSTGQEIITNLSTVAGLKTILTVMRPDIENEDEYVRNVTSRAAAVVAKALGVNQLLPFINAACHSRKSWKARHTGIKIVQQIGILLGIGVLNHLTGLMSCIKDCLMDDHVPVRIVTAHTLSTLAENSYPYGIEVFNVVLEPLWKGIRSHRGKVLSSFLKAVGSMIPLMDPEYAGYYTTEAMRIIRREFDSPDDEMKKTILLVLQKCSAVESITPKFLREEIAPEFFQKFWVRRVALDRPLNKVVTYTTVTLAKKLGCSYTIDKLLTPLRDEAEPFRTMAVHAVTRTVNLLGTADLDERLETRLIDALLIAFQEQTNSDSIIFKGFGAVTVSLDIRMKPFLAPIVSTILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITSVMDLDKLQPPINQILPTLTPILRNKHRKVEVNTIKFVGLIGKLAPTYAPPKEWMRICFELLELLKSTNKEIRRSANATFGFIAEAIGPHDVLVALLNNLKVQERQLRVCTAVAIGIVAKVCGPYNVLPVIMNEYTTPETNVQNGVLKAMSFMFEYIGNMSKDYIYFITPLLEDALTDRDLVHRQTASNVITHLALNCSGTGHEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGLFMNYIWAGLFHPAKNVRKAFWRVYNNMYVMYQDAMVPFYP-VTPDNNEEYI-EELDLVL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .:. : .: ..: .. .: : : .: : . : : : * .: :***.*:::* : :.*: : : :. .* **:**** . :* ** . ..:: *: :: : :* *:**.* :** .:: . . *. :* ***.: ***.****... *::::* :**** **. :**::**:*:. :********::*.***:**:*.**.:********* ******* .* *:***:**:..*** *:::.*****:* ******.*:** ****.***: .****::*.*:*:***:************.**:* .:* ** .*:. *:. *:*:: ** ::* ::::*** : ***** *: **:******* **** *::****:* :*****.***.*** *.* *: ***:***:**** :* *:::*...:.: .:::: ** * **: ** :*:**** : :. *** :*:*:*.: *.::: *:** * :*.*.:.:: : :. **:**:* :** :***.:* ******..* ::::***::. *. *:**:*. * .*:* :*::*:. ***:**** : *:*.*:* :::.:*.::*** *** ********:.*: .*..*:.: *: ***:::** *****:*:*.**: * *.:** *.. .. *...:**************: :* ***:: ***:**:********.:*********** ****:***.***: * *:.***.:**** .** ********::**:*****:*.***** : ******* **********. .: *::*. * * **:: **:* : **:****** : .: .::.* ::** :::* ******::**..:*::**.:*: ***::. ** : * :: * :*: *", "identical_positions": 455, "similar_positions": 313, "identity": "33.31%" }, { "cls_id": "homologset.agr.MGI:1932374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62957-1", "uniprot_id": "CCG7_RAT", "id": "P62957-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAG----------LWRVCFFAG---REKGRCVASEYFLEPEINLVTEN-TENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMN--RPSSSEQ--YFHYRYGWSFAFAASSFLLKEGAGVMSVYLFT----------------------------------KRY------------------------AEEEMYRPHPAFYRPR-------------------LSDCSDYSGQFLQPEAWR---RGRSPS--------------------------------------DISSDVSIQMTQN----------------------------------------YP----------------------------PAIKYPDHLHISTSPC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62956-1", "uniprot_id": "CCG7_MOUSE", "id": "P62956-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAG----------LWRVCFFAG---REKGRCVASEYFLEPEINLVTEN-TENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMN--RPSSSEQ--YFHYRYGWSFAFAASSFLLKEGAGVMSVYLFT----------------------------------KRY------------------------AEEEMYRPHPAFYRPR-------------------LSDCSDYSGQFLQPEAWR---RGRSPS--------------------------------------DISSDVSIQMTQN----------------------------------------YP----------------------------PAIKYPDHLHISTSPC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62955-1", "uniprot_id": "CCG7_HUMAN", "id": "P62955-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAG----------LWRVCFFAG---REKGRCVASEYFLEPEINLVTEN-TENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMN--RPSSSEQ--YFHYRYGWSFAFAASSFLLKEGAGVMSVYLFT----------------------------------KRY------------------------AEEEMYRPHPAFYRPR-------------------LSDCSDYSGQFLQPEAWR---RGRSPS--------------------------------------DISSDVSIQMTQN----------------------------------------YP----------------------------PAIKYPDHLHISTSPC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HJA9-1", "uniprot_id": "A0AC58HJA9_DANRE", "id": "A0AC58HJA9-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRMSSCSSRALTLLSTVFGACGLLLVGVAVATDYWLLMEEGIVLQQNQTVDVKMALHSG----------LWRVCFIAG---TEKGRCVASEYFTEPEIEITTEN-TANILKMVRTATPFPMVSLLFVFTAFIISNVGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMN--RPREPEQ--FFNYRYGWSFAFAASSFLLKEGAGVMSVYLFM----------------------------------KRY------------------------AEEEMYRPHPTLYRPR-------------------LSEGSDYSGQYLHPETWPPPQRARSAS--------------------------------------EISSDISIQLTQNPQHPSKASGQQGTSSPGITAASSPASGTGYQLPSPGSAAPYPHNHPLHPGAHGPAAASQAMPMSAPPAAVPPPHYHTHMRMSASPC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F6NW67-1", "uniprot_id": "F6NW67_DANRE", "id": "F6NW67-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSFSTRALTLLSSVFGACGLLLVGVAVSTDYWLLMEEGIILQQNQTTEVKMALHSG----------LWRVCFVAG---PEKGRCVASEYFTEPEIEITTEN-TANILKMVRTATPFPMVSLLFVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMN--RPREPEQ--FFHYHYGWSFAFAASSFLLKEGAGVMSVYLFM----------------------------------KRY------------------------AEEEMYRPHPALYRPR-------------------LSECSDYSGQYLHPDSWPPPQRGRSGS--------------------------------------EVSSDISIQLNQTPLPPQTKG--SGPSNPPSSSGPSSGASYHLPPASSSSSSSYPHTIHS---SHSSSHVPQSLPMAAPPSAVPPPRYHAHMRMSASPC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2MGK8-1", "uniprot_id": "Q2MGK8_DROME", "id": "Q2MGK8-1", "name": "", "aln": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . * *::.* .: .: :* *:: ** ** : : . **. * ** :* :. .** :** : : ..: * * * .: *: :.: .::. :*:: : *..: * :**:**:*** :::**: *** :: *: . ** .. * :: ** ** : . .*::.* .**:.::** *** :.. ::***: *: . :. *: :.:: * :. : ::.:* *:. .: . . :: .: * ", "identical_positions": 65, "similar_positions": 101, "identity": "6.5%" }, { "cls_id": "homologset.agr.MGI:1932376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHW5-1", "uniprot_id": "CCG8_RAT", "id": "Q8VHW5-1", "name": "Voltage-dependent calcium channel gamma-8 subunit", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESLKRWNEERGLWCEKGVQVLLTTIG------AFAAFGLMTIAISTDYWLYT-----------RALICNTTNLTAG-DDGPPHRGGSGSSEKKDPGG----LTHSGLWRICC-LEGLKRG--VCVKINHFPED--TDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRD-----EEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRGSSEASPSRDASPGG--PGGPGFASTDISMYTLSRDPSKGSVAAGLASAGGGGGGAGVGAYG--GAAGAAGGGG--------------------------------TGSERDRGSSAGFLTLHNAFPKEAASGVTVTVTG--------------------PPAAPAPA--PPAPAAPAPG----------TLSKEAAASNTNTLN-----------RKTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHW2-1", "uniprot_id": "CCG8_MOUSE", "id": "Q8VHW2-1", "name": "Voltage-dependent calcium channel gamma-8 subunit", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESLKRWNEERGLWCEKGVQVLLTTIG------AFSAFGLMTIAISTDYWLYT-----------RALICNTTNLTAG-DDGPPHRGGSGSSEKKDPGG----LTHSGLWRICC-LEGLKRG--VCVKINHFPED--TDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRD-----EEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRGSSEASPSRDASPGG--PGGPGFASTDISMYTLSRDPSKGSVAAGLASAGGGGSGAGVGAYG--GAAGAAGGGG--------------------------------AGSERDRGSSAGFLTLHNAFPKEAASGVTVTVTG--------------------PPAAPAPAPAPPAPAAPAPG----------TLSKEAAASNTNTLN-----------RKTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXS5-1", "uniprot_id": "CCG8_HUMAN", "id": "Q8WXS5-1", "name": "Voltage-dependent calcium channel gamma-8 subunit", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESLKRWNEERGLWCEKGVQVLLTTVG------AFAAFGLMTIAISTDYWLYT-----------RALICNTTNLTAGGDDGTPHRGGGGASEKKDPGG----LTHSGLWRICC-LEGLKRG--VCVKINHFPED--TDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRD-----EEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSR-SSEPSPSRDASPGG--PGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGA-VGAFG--GAAGGAGGGGG---------------------------GGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTG--------------------PPAPPAPA--PPAPSAPAPG----------TLAKEAAASNTNTLN-----------RKTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCW1-1", "uniprot_id": "E9QCW1_DANRE", "id": "E9QCW1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVCEKGIQILLTIVG------AFASFGLMTVAIGTDYWLYS-----------RALICNST---ANNTQEDPHN-----KDKKDPGA----LTHSGLWRICC-LEGVKRG--VCSQINHFPED--ADFDHDGAEYVLRVVRASNIFPILSAILLLMGGVCIAASRFYKSKRNIVLGAGILFVAAGLSNIIGVIVYISAALGDISPKKD-----EDKKWQYSYGWSFYFGGLSFILAEMVGVLAVNIYIEKNKELRCRTRTDIFKS----------TTHAMLRLPSYRFR-RRS-RSSSRSTD-PSRSRDPSPVGGPPGGKNFGMPPSALLSQG-PISVSTLPNPHSRSALPGGDISLYTLSRDPKLGGIGGLG--------------------------------APPLYGTVDRATLYQLHNCFPKE--GGGGMMMSGTLPSLKSHNPSGVQNSSNSNAPLSNSVPSSQPPPFSSSTGERDRGMGTLDRLGKGDRESNSNTLN-----------RKTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P8P0-1", "uniprot_id": "A0A8M1P8P0_DANRE", "id": "A0A8M1P8P0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGKARHIPPAMVWCERGIQVLLTTVG------AFAAFALMTVAIGTDYWLYA-----------RAFICNST---ANSSQDDPHN-----KDKKDPGA----LTHSGLWRICC-LEGLKRG--VCSQINHFPED--ADYDQDAAEYLLRVVRASSIFPILSAILLLLGGVCVASSRFYKTKRHIILGAGILFVVAGLSNIIGVIVYISAALSDISPKKD-----EDKKWHYSYGWSFYFGGLSFILAEVVGVLAVNIYIERNKELRCRSRTDLFRS----------TTSAVLRLPGYRFR-RRSSRSSSRSTAEPSRSREQSPTSAIAP-KNFGPPLAAGPP---PFSVATLPNPHTHSGGGGGGGGGGGMG-DISMYTLGREG--------------------------------KPPMYGTVDRATLYQLHNYFPTKEGGGGGALMTGTLPSISKSNLAASAN-ATLNTSSSSGPQQAPLSAGSSATMERDRGLGTLDRLGKGD-SSNTNTLN-----------RRTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2MGK8-1", "uniprot_id": "Q2MGK8_DROME", "id": "Q2MGK8-1", "name": "", "aln": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFIN-LQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * . ..:. ** . . ** : * :... : .: . * *. *:*.** :* * *:. . * :*::*.:: :*.: : .* * : : :.::*::. : . . : :. :.*****:.:** :**:*.*** .: ..* : : *** **:: :.**::*.:*** : ::*: :* :* : *: ... : . . . * . . . . . * . : . * * .. .. . . .. :.: **:: : *:*. ", "identical_positions": 60, "similar_positions": 112, "identity": "5.99%" }, { "cls_id": "homologset.agr.MGI:1932386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LHF1-1", "uniprot_id": "A0ABK0LHF1_RAT", "id": "A0ABK0LHF1-1", "name": "Intraflagellar transport protein 122 homolog", "aln": "MGANRPWPMPGPRRTPWQRQWLGLCALAATTPARRPTPRSPHPAPGSRRPRKQRMAADADSPQNRWQPPRRQRRGRRKGRRRASIYDLAFKPDGTQLILAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQCVSYNPVTHQLASCSSSDFGLWSPEQKSVSKHKSNSKITCCSWTNDGQYLALGMSNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSR-----------------------------------------------------------EEHNDILAVADWGQKLSFYQLSGKQIGKDRPLNFDPCCISYFTKGEYILVGGSDKQVSLFTKDGVRLGTVGE-QNSWVWTCRVKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCRELVKKIAIYKNRLAIQLPEKILIYELYSDDSADMHYRVKEKIVKKFECNLLVVCADHIILCQEKRLQCLSFSGVREREWQMESLIRYIKVIGGPAGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRNKLAVVDENDTCLVYDIHTKELLFQEPNANSVAWNTQCEDMLCFSGG-GYLNIKASTFP-VHQQKLQGFVVGYNGSKIFCLHVFSMSAVEVPQSAPMYQYLDRKMFKEAYQIACLGVTDTDWRELAMEALEGLEFETAKKAFTRVQDLRYLELISTIEERKKRGESNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALNMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNINEPKAAVEMYISAGEHAKAIEISGSHGWVDMLIDIARKLDKAEREPLLMCARYFKKLDSPGYAAETYLKIGDLKSLVQLYVDTKRWDEAFALGEKHPEFKDDIYVPYAQWLAENDRFEEAQKAFHKAGRQGEAVRVLEQLTHNAVVESRFNDAAYYYWMLSMQCLDMAQ-DPAQK--DVMLDKFHHFQHLAELYHGYQTIHRYTEEPFSFDLPETLFNISKFLLHSLT-KATPLGISKVNTLFTLAKQSKALGAYKLARHAYDKLRGLQIPARIQKSIELGTLTIRSKP--FHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYEVLHLVEFYLEEGITDEEAVALIDLEAPRHKREGKWQETSSNNSQTLRLDETMDSIGEDDPFTAKLSFEQGGSEFVPVVVSRSVLRSMSRRDVLIK-RWPPPLQWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHACCPYCRRRIDDTGP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NWV3-1", "uniprot_id": "IF122_MOUSE", "id": "Q6NWV3-1", "name": "Intraflagellar transport protein 122 homolog", "aln": "MRAVLTW----------------------------------------------------------------------RDKAEQCIYDLAFKPDGTQLILAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQCVSYNPVTHQLASCSSSDFGLWSPEQKSVSKHKSSSKITCCSWTNDGQYLALGMANGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSR-----------------------------------------------------------EEHNDILAVADWGQKLSFYQLSGKQIGKDRPLNFDPCCISYFTKGEYILVGGSDKQVSLFTKDGVRLGTVGE-QNSWVWTCRVKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCRELVKKIAIYKNRLAIQLPEKILIYELYSEDSTDMHYRVKEKIVKKFECNLLVVCADHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPAGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRNKLAVVDENDTCLVYDIHTKELLFQEPNANSVAWNTQCEDMLCFSGG-GYLNIKASTFP-VHQQKLQGFVVGYNGSKIFCLHVFSMSAVEVPQSAPMYQYLDRKMFKEAYQIACLGVTDADWRELAMEALEGLEFETARKAFTRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALDMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNINEPKAAVEMYISAGEHAKAIEISGSHGWVDMLIDIARKLDKAEREPLLMCACYFKKLDSPGYAAETYLKIGDLKSLVQLYVDTKRWDEAFALGEKHPEFKDDVYVPYAQWLAENDRFEEAQKAFHKAGRQGEAVRVLEQLTHNAVVESRFNDAAYYYWMLSMQCLDMAQ-DPAQK--DAMLDKFHHFQHLAELYHGYQTIHRYTEEPFSFDLPETLFNISKFLLHSLT-KATPLGISKVNTLFTLAKQSKALGAYKLARHAYDKLRGLQIPARIQKSIELGTLTIRSKP--FHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYEVLHLVEFYLEEGITDEEAVALIDLEAPRHKREGKWRETSSNNSQTLKLDETMDSIGEDDPFTAKLSFEQGSSEFVPVVVNRSVLRSMSRRDVLIK-RWPPPLQWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHACCPYCRRRIDDTGP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBG6-1", "uniprot_id": "IF122_HUMAN", "id": "Q9HBG6-1", "name": "Intraflagellar transport protein 122 homolog", "aln": "MRAVLTW----------------------------------------------------------------------RDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSRWESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGE-QNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGG-GYLNIKASTFP-VHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCLDIAQ-DPAQK--DTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSLP-KDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAKP--FHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIK-RWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYH1-1", "uniprot_id": "IF122_DANRE", "id": "Q6NYH1-1", "name": "Intraflagellar transport protein 122 homolog", "aln": "MRAVPTWIDKVHD----------------------------------------------------------------RDKVEQCIYDLAFRPDGSQLIVAAGNRVLVYDTADGTLIQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQCVSYNPVTHQLASCSSGDFGLWSPEQKSVSKHKVSSKITCCGWTNDGQYLALGMMNGVVSIRNKNGEEKVKIERPGGSSSPVWSIAWNPSK-----------------------------------------------------------DEHNDILAVADWGQKLSFYQLSGKQIGKDRSLTFDPCCVSFFSKGEYMVLCGSDRQAALYTRDGVRLGSIAE-QNAWVWTCRVKPDSNYVVVGCQDGTIAFFQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCRELVKKIAIYRSRLAIQLPEKILIYELLSDDSADMHYRVKEKICRRFECNLLVVCSQHIILCQEKRLQCLSFTALRQREWLMESLIRYIKVIGGPAGREGLLVGLKNGAILKIFVDNPFPITLLKQNTSVRCLDMSSNRSRLAVVDEHNTCLVYDIHTRELLFQEPNANSVAWNTQCEDMLCFSGG-GFLNIKACSFP-VHQQKLQGFVVGYNGSRIFCLHVYSMAAVEVPQSAPMYQYLERRMFQQAYNIACLGVTDSDWRDLATEALEGLDFHTAKKAFIRIRDLRYLELISSIEERKKRGETDNQLFLADVFAYQGKFHEAAKLYRRSGQDGRALSMYTDLRMFDYAKDFLGSADPKDTKLLMKKQADWAKNSREPRAAAEMYLSAGEHLKAIQIIGEHGWVDMLIDVGRRLDKAERAALSRCAVFLQQLQQHGYAAELYSKMGDLRALLQLHVHATHWDEAFSLVEKHPQFRDDVYVPYAQWLAEHDRFEEAQRAFHKAGRQAEAVRVLEQLTHNAVVESRFSDASYYYWMLSMQCLDIAREDSEQK--QEMLKKFHSFQHLAELYHVYHSVHRYMSEPFSSNMPEILFNISRFLFHNLS-THTPMGISKVDTLYALAKQSKLLGAYKVSRHAFEKLQSLKIPARYQDSVELSSLTVRSKP--YRDNEDLIPMCYRCSTNNPLLNNQGNSCINCRQPFIFSASSYEVLPLVEFYLDQGISDEEAVSLIDLEVPRVEKNKSWQEMSSGESQCLKLEDGPDDP-EDDPFTAKLSFEQGGSVFVPVRVSRAVLRSMSRRDVLIK-RWPAPLSWQYYRSLLPDVSITMCPSCFQMFHSEDYELLVLQHSCCPFCRRPIDESC---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSJ6-1", "uniprot_id": "Q9VSJ6_DROME", "id": "Q9VSJ6-1", "name": "Intraflagellar transport protein 122 homolog", "aln": "MRGVLKWLERIEFPN--------------------------------------------------------------SKDNEISVHNVCYAPDGSQLVVAAGDRLLIYDPNDGSLLNTLKAHKDTVNCVAYSRDGKRFASGASDKMVIVWSPQLEGLLKYSHGDSIQCMSFNPVSHHLASCSLSDFAFWSADQKAVQKYKISARVNGCSWTNDGQYLILGLANGTISIRNKLGEEKGRIDRPGGPNSNVFSVQCCPASG----------------------------------------------------------PGSVDTIGVVDWSQTLSFHTLSGQMIGKERTLGFDPLCLQYFPNGEFCLVGGCTGGLHFFTREGIRLGTLGDTFDTWIWTVALHPNGQSYTIGCQDGTLACFNIASSTVHALYRERYAFRENMCDVIIQHLISGQKVRIKCRDLVQKIAIYRNRLAVQLPERVVLYELSSGEDQPMHYKVREKIQQKFDCSLLVVCGRHIVLCQEKRLQCLDFMGVLQREWIMDSFIRYIKVTGGPVGREGLMVGLKNGQVFRIFLNNSLPLLITTAVSAVRCLDINSKRSKIAVVDDVGRLVVRDVINDTILYQDTGVNSVTWNTHLDSMLCYTHTTGGLSVRVGNLPPRAPQNMHGVVVGLCGATAFCLRGNIMHNTPLALGSTMWQFIEAGLFDEAYQVACLGVTTSDWEGLAQSALEALHINIARDAYVKVRNLPWLKLIGELRDQQQRSAVPKEVLLAENCAFAGKFKEAARLFLKCGQSSRALEMYTDLRMFDLAQEYIKDGTDQEKKELVRKRAEWAYSVKEPRAAAELLLSAGENQKAIDIVAEQGWADVLYDIGRRLSLTERDSLESVAQNLKTLKALPLAAEIFKKLGDEAQVVQLHIEVRDWPEAFRLAESLPELLPTVHYQHGQWLAETDQFIEAHQAYIKAGRTKEANRLLKQLSNTAIVEERYLDASYFYWLLAKQHLDVYHAKEEQNPVDHHLTEYKNHLRVAKVYYAYSVIYSYMKEPFTTHSPVSLFNVSRFILNEVEHKGVPKGVSMFSVLFTLAKQAKFLQANKLCLLINKRLQSLKPPAGVQEQIDLNFLNSKACKSGFNDPEELLPLCYKCSNYSQHLN--SNCCPTCRQDYIFSFVSFEILPLVQFYPEVDISDAEAERLLLAPAKHAE--------------------------DSDPFNEDVAS------ALPLSLDRNGLRAIDPNHVLILKRRGKNVRNVYYRNILPDLQVTYCPQCLLLFYAEDFELQVLQKGHCPFCHTSSEKLMEDF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * . .: ::.: ***:**::***.*:*:**. **:*::.**.***** ****::********::** :*:*:.:***:***:*.*:***:*:**::*:***** .**.:**.:**:*.*:* .::: *.******** **: ** :***** **** :*:****. * ::*: *: * :.*.**.*.:**: ***: ***:*.* *** *:.:*.:**: :: *. ::*::*:***::.: ::*:** :*:.: .:******:: ::: ****.**::***:*:.* ***:****: *******::**:*****:.***:****::::*** * : ***:*:*** ::*:*.*****. **:**********.* .: :*** *:*:****** *** *****:****** :::**::* :.: : . ::*****:.:.*.::****: . :* *: . :*:*:...***:***: :.***:: * *.::. .:* *:::*.*** *: ***: : . :. .:.*:*::: :*.:**::****** :**. ** .***.*.:. *:.*: ::::* :*:**. :.::::*. ::::**: :: ***:***:*: :.*:.. **.***** **: *:::: .. ::.* *: *:*:** . .**:**.*: :****: ***:* ..:**.*:* *:.*:*. :** .* * :: *. *** : *:** ::**::.. * *** * *. *:: :: :.***** *:* **::*: **** ** ::*:**::.*:.*.*: **:*:**:*: * **: : . *: : * :: . ::*::*: * :: : .:**: . * ***:*:*:::.: . .* *:* .. *::****:* * * ::. .:*:.* ** *..::*. *. :: :.* *:*:*:**:**. . ** .* * .*** :*** *:::* **:** : .*:* ** *: . : : :.***. .:: :*: :.* **::. ..*** * : *:*.:*** .:* **.*: :*::**:** ***:. **:*: :. ", "identical_positions": 484, "similar_positions": 413, "identity": "36.58%" }, { "cls_id": "homologset.agr.MGI:1932389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RAA8-1", "uniprot_id": "M0RAA8_RAT", "id": "M0RAA8-1", "name": "Toll-like receptor 9", "aln": "MVLCRRTLHPLSLLVQAAMLAEALALGTLPAFLPCELKPHGLVDCNWLFLKSVPHFSAAEPRSNITSLSLIANRIHHLHNLDFVHLPNVRQLNLKWNCPPPGLSPLHFSCRMTIEPKTFLAMRMLEELNLSYNGITTVPRLPSSLTNLSLSHTNILVLDASSLAGLHSLRVLFMDGNCYYKNPCNGAVNVTPDAFLGLSNLTHLSLKYNNLTEVPRQLPSSLEYLLLSYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPDLCTECRQKSLDLHPQTFRHLSHLEGLVLKDSSLHSLNSKWFQGLVNLSVLDLSENFLYESINKTSAFQNLTRLRKLDLSFNYCKKVSFARLHLASSFKSLVSLQELNMNGIFFRLLNKNTLRWLAGLPKLHTLHLQMNFINQAQLSVFSTFRALRFVDLSNNRISGPPTLSRVAPEKADEAEKGVPWPASLTPALPSTPVSKNFMVRCKNLRFTMDLSRNNLVTIKPEMFVNLSHLQCLSLSHNCIAQAVNGSQFLPLTNLKVLDLSYNKLDLYHSKSFSELPQLQALDLSYNSQPFSMQGIGHNFSFLANLSRLQNLSLAHNDIHSRVSSRLYSTSVEYLDFSGNGVGRMWDEEDLYLYFFQDLRSLIHLDLSQNKLHILRPQNLNYLPKSLTKLSFRDNHLSFFNWSSLAFLPNLRDLDLAGNLLKALTNGTLPNGTLLQKLDVSSNSIVFVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLDVSSNPLHCACGAPFVDLLLEVQTKVPGLANGVKCGSPRQLQGRSIFAQDLRLCLDDVLSRDCFGLSLLAVAVGTVLPLLQHLCGWDVWYCFHLCLAWLPLLTR-GRRSAQALPYDAFVVFDKAQSAVADWVYNELRVRLEERRGRRALRLCLEDRDWLPGQTLFENLWASIYGSRKTLFVLAHTDKVSGLLRTSFLLAQQRLLEDRKDVVVLVILRPDAHRSRYVRLRQRLCRQSVLFWPHQPNGQGSFWAQLSTALTRDNHHFYNRNFCRGPTAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQU3-1", "uniprot_id": "TLR9_MOUSE", "id": "Q9EQU3-1", "name": "Toll-like receptor 9", "aln": "MVLRRRTLHPLSLLVQAAVLAETLALGTLPAFLPCELKPHGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCPPTGLSPLHFSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLDANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNLTKVPRQLPPSLEYLLVSYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPNPCIECGQKSLHLHPETFHHLSHLEGLVLKDSSLHTLNSSWFQGLVNLSVLDLSENFLYESITHTNAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFRLLNKYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTLSEATPEEADDAEQEELLSADPHPAPLSTPASKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVNLSRLQCLSLSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPFSMKGIGHNFSFVTHLSMLQSLSLAHNDIHTRVSSHLNSNSVRFLDFSGNGMGRMWDEGGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNLEVLDLAGNQLKALTNGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLDVRSNPLHCACGAAFVDLLLEVQTKVPGLANGVKCGSPGQLQGRSIFAQDLRLCLDEVLSWDCFGLSLLAVAVGMVVPILHHLCGWDVWYCFHLCLAWLPLLAR-SRRSAQTLPYDAFVVFDKAQSAVADWVYNELRVRLEERRGRRALRLCLEDRDWLPGQTLFENLWASIYGSRKTLFVLAHTDRVSGLLRTSFLLAQQRLLEDRKDVVVLVILRPDAHRSRYVRLRQRLCRQSVLFWPQQPNGQGGFWAQLSTALTRDNRHFYNQNFCRGPTAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR96-1", "uniprot_id": "TLR9_HUMAN", "id": "Q9NR96-1", "name": "Toll-like receptor 9", "aln": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELT-ATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * :********** :** :**************:*****:**********:** * . .*:* *** :*******: **.**..:*:********* ****:**.*:***** ****: *********.* *** **.** .*********:**: *****::**.************* *::*:*.*:***.************* ***:**.******:*** ****.********:*****************: * ** :: .***:** ***:*********** **:.**:** ** **********:.*.:*.***.**:****:***** *:****:* **.** .**:*:**:*:***** *:: *** ** ** *:**:***********.:* :* .**:****:*****.. *: .: :** .*: ... ** .** *::* .*..:.**:*********::****.:**:**** ****.*:************.*:*****:******* :**:***:*:***********.*:*:******:::* *: ******:**::**.:* *.*:. ******.:*:** * .***:***.* .*: ******.** * **.* ***** * :***:*:**:* ** ***:*. ****** *******:** ** *::****.*** *.*.**: * **:*:*** * *****:*****:. * :*** :*********.*:*:*****: ****.. ****** **** ************:.** ***.*******:* :*:*:******:************ * . *. ::***********:************* :*** *** *******:******:*********:**************:******:********************** **.:*****************:**:**.** .*****. ******:****:***:*****", "identical_positions": 732, "similar_positions": 189, "identity": "70.86%" }, { "cls_id": "homologset.agr.MGI:1932395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M853-1", "uniprot_id": "F1M853_RAT", "id": "F1M853-1", "name": "Ribosome-binding protein 1", "aln": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHH-QKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPMRVPAVAVAPTSVHSSVGRTPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEASPKEVPMVAVPPVGSKASAPATSSQGKKGQGAQNQAKKGEGAQNQAKKGEGVQNQAKKGEGAQNQVKKGEGAQNQAKKGEGAQNQAKKGEGTQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQN--------------------QAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGLQNQGKKGEATQKQDKKIEGAQNQGKKPEGTPNQGKKGEGAQNQGKKGEGAQNQ-----------------------------------------------------------------------------------------------------------------------------------GKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGSPSQNIKVEGMQNQGRKAEGTPAQGKKMEAAQNQGKKAEGVQSQGKKGEGSQNQGKKGDGNPNQGKKGEGAPNQNRKTDTVANQGTKTEGVSNQVKKSEGSPNQGKKAEGAPNQGKKVEGSPNQAKKVDAAAGQGKKSEMTPAQGKNASMVQSQEAPKQEAPAKKK--SKKKGEPGP--PDCDSPLFLPYKTLVSTVGSMVFSEGEAQRLIEILSEKTGVIQDTWHKATQKGDPVAVLKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYQDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQILQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSDLHGQLKEARAENS--------------------------------------------------------------------QLTERIRSIEALLEAGQA---QDSQAS--------RAEADQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLRE---KNWKAMEALALAERACEEKLRSLTQAKEES----EKQLHLAEAQTKEVLLALLPELSIPAHQNYADWLQEVKEKGSELLKKPPVSVEPS------LDIVSKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELQKSRFTVKHLEDLVEKLRGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLDSQSQLEEAKSEAQKQSNELALVRQQLSDMRSHVEDGDVAGSPA----VPPAEQDPVKLKTQLERTEATLEDEQTRRQKLTAEFEEAQST-ACRLQEELEKLRAAGPLESSGIEEVTQLKERLEKEKRLTSDLGRAATKLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKEGTSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PL5-1", "uniprot_id": "RRBP1_MOUSE", "id": "Q99PL5-1", "name": "Ribosome-binding protein 1", "aln": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHH-QKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPGP--PDCDGPLFLPYKTLVSTVGSMVFSEGEAQRLIEILSEKTGVIQDTWHKATQKGDPVAILKRQLQEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENS--------------------------------------------------------------------QLTERIRSIEALLEAGQA---QDTQAS--------HAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLRE---KNWKAMEALALAERACEEKLRSLTQAKEES----EKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPT-LEPS------MDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALVRQQLSDMRSHVEDGDVAGSPA----VPPAEQDPMKLKTQLERTEATLEAEQTRRQKLTAEFEEAQRT-ACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKEGTSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2E9-1", "uniprot_id": "RRBP1_HUMAN", "id": "Q9P2E9-1", "name": "Ribosome-binding protein 1", "aln": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHH-QKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDPAPNVTVLLREPVRAPAVAVAPTPVQPPIIVAPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLTSKAAILETAPKEVPMVVVPPVGAKGNTPATG-------------------TTQGKKAEGTQNQSKKAEGAPNQGRKAEGTPNQGKKTEGTPNQGKKAEGTPNQGKKAEGTPNQGKKAEGAQNQGKKVDTTPNQGKKVEGAPTQGRKAEGAQN--------------------QAKKVEGAQNQGKKAEGAQNQGKKGEGAQNQGKKAEGAQNQGKK-AEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQ-----------------------------------------------------------------------------------------------------------------------------------GKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEG----------AQNQGKKAEGAQNQGQKGEGAQNQGKKTEGAQ------------GKKAERSPNQGKKGEGAPIQGKKADSVANQGTKVEGITNQGKKAEGSPSEGKKAEGSPNQG----------KKADAAANQGKKTESASVQGRNTDVAQSPEAPKQEAPAKKKSGSKKKGEPGP--PDADGPLYLPYKTLVSTVGSMVFNEGEAQRLIEILSEKAGIIQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENS--------------------------------------------------------------------QLTERIRSIEALLEAGQARDAQDVQAS--------QAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLRE---KNWKAMEALATAEQACKEKLLSLTQAKEES----EKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPS------SDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEEAQTS-ACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAEDGSSSKEGTSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A4D7-1", "uniprot_id": "B8A4D7_DANRE", "id": "B8A4D7-1", "name": "", "aln": "MDIYDPQTLGIVVFGGFMVFSAIGIALVSTFSMKETSYEEALAKQRKEQGKTQSSQKSDKKKKDKVAEKKNRSKKKEDKPNGKLLESESTAEVSEVANEPSPPIPLAPEQVAVPAPKQEASIQKSVQPTSSQKTTSPA---LAQKSVPAVQAQKSAPPAPAQKAAPPAPAQKSAPPASAQKSAPAPPTQKTSPASP---------------------------------------------NQKSSPAPPTQKTSPNPSGKKSASPPPAQKPASPAPASKSAPAAPAQKSTTVAPSQKSASEAPAQKATPPA-------------------------PAQKAATTAPAQKAAPPAQAQKATSSSSSQKPTPPAPVQKSAQPAPTEKSAKAQKAASTAPAQKSSPPAPPQKPASNPQPQKGTPLAASQKSETPTEKSVKAQKAAPPAPAQKSSPPDRKPSPSAPASSQNS-----------------------------------------------------------------------------------------------------------------------------------------------------TSGITPAPPCPTVEDAPPAPSP-----------------------------------------------------------------------------------------KGKRKKKSKAESASAEVQPKSVAPLEVVTKKVPVMAVPPVGTQKAAAV------------------------------------TAVPVKAEESKQDAPPKKKSGSKKKAEPAVAADPADSPLYLPYKALLSTVRSMVFSEGEAQQLIQILSDKAGIIQDTWQKATQKGDPVVLLKKQLEERDKQLAAEQEDAAAAKGRLRDLNKELSVEKSKVASIETRLSSQLSKREQDIIALQARMQASYQDHLAESQQLNAKLLALQDQLEKGPNAQLARLQQENSILRDALNQATSQTESKQNAELAKLRQDCVRLNKELAEKNDALQADEQLRKNLETKAASVEKQLNQMQASRANAEQALQKRLEEVSEELRQTQSNRNNLQAQLEQAQKDAAALAEAKARVASVEVEMKERTGHLESLQSQLKQTQTEREQQLKEQNDISETVTAELEQARKSLKEKEIAVSTLEEELTQLK----NTISNQVNQVDS-----TTDVQHLQQSIKEKDTQIAALQGELQQAKEKSSDLNKLENQEMLEQLQKSLKEKESREKLFEEQIRQCKEQCSTKLADSTAQLDSLHKRISEKESLMTTLQQEVQQLKELNQSQSKSFESLEDMLKSFQGETKEVLHSLFPHINIETAK--TKWLQDFAVKAQELLNQKQQSQESQ-QSTEIVEMMGKLQAAQESQCTLQSECEQYRIVLAETEGMLKTLQKSVEEEESVWRTKISESEDKLRMALKKVQELEETAERLRAESQGNQQLQEQVKLLEAQLEEQLQSASTDSQSQSEEMAHLKQALADTESQLNSAQKEAQTQREELLQVKQQLNDVTKRAQGVAENGQPE---------AEECQVQDQLEQTLEKLQGEQALNQQLSAEVEQAQETLKIHLQSHLEQMKSA--EDTAAMGDVVQLKECLEKERKMTKDLGQAATKLQQLLRNSQDQLAKEKEKVRSLHDQLQNKEGDGELKQGTSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LXR3-1", "uniprot_id": "Q1LXR3_DANRE", "id": "Q1LXR3-1", "name": "", "aln": "MDVYDPQTLGIVVFGGFMVFSAIGITLVSTFSMKETSYEEALAKQRQDSGKTQS-QRSDKKK--KASEKKTKSKKKEEKQNGNLPESE-------------------PEPEPIPEPVVENSEPK---------------------AVPQVEPEP-------QPVAVPEPVPEVKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPVVSEPVPNIVECA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APPTVSAVVAPLAPSP-----------------------------------------------------------------------------------------KEKKKKK------VAKVEPAPVKPVEVPIVVAKVEPVVAESVVKAVVS------------------------------------PEVAAVPEEPKVETPTKKK--PKKKAEPAVSVEEVDIPQPSPYKTLVSSLNSALFSESETQKLFEIISKKAG--RDSWQLASQKGDPLATLKKQLEEKEKQLTAEQGNVAAAKTRVRELTKELNTAKNKIASTEARMSSELSARGQEITALQARMQTSYQEHVNESQQLNSKIQSLQEQLENGPMAQLARLEQENSILRDALNQATSQAESRQNAELAKLRQDCVRLNRELKECTASQQFEEERRKSLETKLAAAEEQLKQTQASCVGTEQALQKKLDKLKEELQEAQQGSNKLQTQVDAAKEQAKTLADLQERMRVTETELKNRCEELEILRAQENPTVEIEATVQKINSEEAEQLRSSLKEREEQLTSLEAELTQLREELETVKRAQAEETQNRVNEADTRCREYTTEIQQLKTSVKEKEDLVASLQAELEKMEST----NTVEAEPPFENLEK-----DARMISLEEELQQIKEEMERMKAKSNELRE---KNYAAVEALAAAERLSEERLSQAKTAQS----AVEQQLSSFQTDARNAFQTLFPHISIETHQ--TNWLEAFTNEAQKSLTHSPAEQEHMSVSSDVMDLQQKLTLSEDNQRTLQAECEQYRATLSETEGMLKALQKSVEDGELSWTSKISEVEQQKQTALDQVKILEKTIEKINAEMQDTNQLKGQVMLLEAQLEKQLESVTIS-QIYAEEMAQLKTLLSDTQTQLLSAQADAQQQRAELSQVKMQL------------------------------------EETMSKVQTEEVVPHQM----------------------------------------EKPEEEKQSMADLGLTDTEAQQLLD---------KDKGKSLQEQDTE-----DSKEGTSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**.****:********.***** *****************:**:: .**: *: :*** *. *** ::****:* **:: : : .: . . . *. *:. * : . : * : . : : . . * . : *: : :. . * . ** . : * .* ::*.*** .:**.**. * * ***:*:*:: * :*.*.*:*:*::*:*.*:* :*:*: *:*****:. **:**:*::* *::** :.*.** ::*:*.**: * * *: *:::..:* * *:* *:*****:**::*: * ***:.*: :**:***:** :*****:****************.**:**:*******: ::.:** * . : : :*: ** **:* *: *:*: * *** :*:****:*:::..** .:* . .*::: : *::: :*: : :: *.*::.: .*. *:.* : : . :* ::. : : : *. : . . :: :. ::: :*:: : :* . ... : *. *:* : : ::* . . ::. *. * : :: :.: :*:* :.: : : :.**: . :. *.: * :: ** :::.* :**:**:*** *:******: ******: * * :*:. *:: : : *: **. *::..* :..:*:: :. ***:**::: :.: . * ::*:* *: * ::::** *: :** * ** *: ** * * :: *:. ::: * *:*:: *** : . *:** *:. :.*::* : . *:****", "identical_positions": 301, "similar_positions": 297, "identity": "17.64%" }, { "cls_id": "homologset.agr.MGI:1932403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4D6-1", "uniprot_id": "CP4X1_RAT", "id": "Q8K4D6-1", "name": "Cytochrome P450 4X1", "aln": "MEASWLENRWARPLHLALVFCLALVLMQAVKLYLRRQRLLRDLRP---FPGPTAHWLLGHQKFLQEDNMEK--LDEIVKEYPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKTQYLHQLMTPFLGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTEKIIQDRKKTLKDQVNQDDTQTS--QNFLDIVLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGS-SITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTR-PPAFSSHTVLRPKHGIYLHLKKLPEC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A152-1", "uniprot_id": "CP4X1_MOUSE", "id": "Q6A152-1", "name": "Cytochrome P450 4X1", "aln": "MEASWLETRWARPLHLALVFCLALVLMQAMKLYLRRQRLLRDLSP---FPGPPAHWLLGHQKFLQEDNMET--LDEIVKKHPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKMQYLHQLLTPCIGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQYTEKIIQDRKKILKNQVKQDDTQTS--QIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGS-SITWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALILLHFQVAPDLTR-PPAFSSHTVLRPKHGIYLHLKKLLEC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N118-1", "uniprot_id": "CP4X1_HUMAN", "id": "Q8N118-1", "name": "Cytochrome P450 4X1", "aln": "MEFSWLETRWARPFYLAFVFCLALGLLQAIKLYLRRQRLLRDLRP---FPAPPTHWFLGHQKFIQDDNMEK--LEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILKPKNGMYLHLKKLSEC----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V7G5-1", "uniprot_id": "C4AA1_DROME", "id": "Q9V7G5-1", "name": "Probable cytochrome P450 4aa1", "aln": "MFVEKVLERTTN-LELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVG--TEINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMIQRRR-----QIQNNNNGNSERKCLLDHMIEIS-ESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLKERDHPLIAH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : * :. : *. :: * : :. .:* : **.: :..*.: :**: :: :.:: : .. : . *: * * : * : *:...: :: :: :* ** .*.:* :** *: *.** ::*: :: :..: : : :: : * ::: :::* ***: :..:. : : :.. .. : :: *: . * *:: : . : : ::: * .:** *: :::::. . : :** ::. . . *:: *: *. **: **:*: .*:::: *: *: *** *:** *: *: *.. : * :* *: * *****: ** *.:* *:*.*.: : :.. :**** .*.:. :. *: . :: :*: *:* **: ***::*** *:****:*.* ***:.**::*:*. :: * ::: . : . : . : *:.. *::::**: . ", "identical_positions": 113, "similar_positions": 196, "identity": "21.73%" }, { "cls_id": "homologset.agr.MGI:1932404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M3B3-1", "uniprot_id": "F1M3B3_RAT", "id": "F1M3B3-1", "name": "PH-interacting protein", "aln": "-MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPNIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG---TLKINPRPTKFTERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAG-QNLQGIEDKITKMKVTMVAWDRHDSTVITAVNNMTLKVWNSYTGQLIHVLTGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLVIFGFGSS-SKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSS---------GLNQVLSQQAIQD-----------------ISPLDSMIQRLQQEQDLRRSGEAAVSSAGR------------LNRGSVSSTSEVH----SPPNVGLRRSGQIEGVRQMHSNAPRSEIATERD--------LVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRK--------HLTVAKENKILTVSKNHAHEHFLDLGDSKKQQAN----QHNYRTRSALEETPRPLEEIENGTSSSD-EGEVLAVSGGTSEEE---ERAWHSD-GSSSDYSSDYSDWTADA-GINLQPPKKVPKHKTKKQDSSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNRIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKHQHFLLFRDQTCYNIIPLYNSMKKKVLSDS-----EEEEKDADVPGTSTR--KRKDHQPRRRLRNRAQSYDIQAWRKQCQELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALR------------------------FHKRNTITKRR------------------------------------------------------------------KRRNRSSSL-----------SSSAASSPERKKRILK---PQLKSE------------------------------------------------------ISTSPFSIPTRSVLPRHS-------------AAQMNGKPESSSVVRTR-----SNRIAVDPVVTEQPSTSAATKAFVSKTNTSAMPGKTILENSVKHSKALST---------------------------------------------------------------------------------------------------------LSSPDQLTFSHGTKNNSAKENMEKEKPVKRKMKSSVFTKASPLPKSSAVVDQGDCKNNVLIPGTIQVNGHGGQPSKLVKRGPGR----------------------------------KPKVEVNTSSGEVTHKKRGRKPKNLQCTTKQENSEQNNMHPIRGDVVPSSTCSFLSETNVVKED--LLQKKSRGGRKPKRKMKTQNLDSELIVPTNVKILR-----------------------RSNRKKADDPIDEE------EEFEELKG----SEPHMRTRN------QGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDD9-1", "uniprot_id": "PHIP_MOUSE", "id": "Q8VDD9-1", "name": "PH-interacting protein", "aln": "-MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG---TLKINPRPTKFTERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAG-QNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSS-SKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSS---------GLNQVLSQQANQD-----------------ISPLDSMIQRLQQEQDLRRSGEAGVSNASR------------VNRGSVSSTSEVH----SPPNIGLRRSGQIEGVRQMHSNAPRSEIATERD--------LVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRK--------HLTVAKENKILTVSKNHAHEHFLDLGDSKKQQAN----QHNYRTRSALEETPRPLEELENGTSSSD-EGEVLAVSGGTSEEE---ERAWHSD-GSSSDYSSDYSDWTADA-GINLQPPKKVPKHKTKKPESSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRPWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIK--------DQTCYNIIPLYNSMKKKVLSDS-----EEEEKDADVPGTSTR--KRKDHQPRRRLRNRAQSYDIQAWKKQCQELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNFKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALR------------------------FHKRNTISKKR------------------------------------------------------------------KKRNRSSSL-----------SSSAASSPERKKRILK---PQLKSE------------------------------------------------------VSTSPFSIPTRSVLPRHN-------------AAQMNGKPESSSVVRTR-----SNRVAVDPVVTEQPSTSSATKAFVSKTNTSAMPGKAMLENSVRHSKALST---------------------------------------------------------------------------------------------------------LSSPDPLTFSHATKNNSAKENMEKEKPVKRKMKSSVFSKASPLPKSAAVIEQGECKNNVLIPGTIQVNGHGGQPSKLVKRGPGR----------------------------------KPKVEVNTSSGEVTHKKRGRKPKNLQCAK-QENSEQNNMHPIRADVLPSSTCNFLSETNAVKED--LLQKKSRGGRKPKRKMKTHNLDSELIVPTNVKVLR-----------------------RSNRKKTDDPIDEE------EEFEELKG----SEPHMRTRN------QGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWQ0-1", "uniprot_id": "PHIP_HUMAN", "id": "Q8WWQ0-1", "name": "PH-interacting protein", "aln": "-MSCERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG---TLKINPRPAKFTERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAG-QNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSS-SKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSS---------GLNQVLSQQANQE-----------------ISPLDSMIQRLQQEQDLRRSGEAVISNTSR------------LSRGSISSTSEVH----SPPNVGLRRSGQIEGVRQMHSNAPRSEIATERD--------LVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKTYRSEEKRK--------HLTVPKENKIPTVSKNHAHEHFLDLGESKKQQTN----QHNYRTRSALEETPRPSEEIENGSSSSD-EGEVVAVSGGTSEEE---ERAWHSD-GSSSDYSSDYSDWTADA-GINLQPPKKVPKNKTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGELTENGLTLEEWLPSTWITDTIPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQLEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDGECRSLIYKPLDGEWGTNPRDEECERIVAGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIK--------DQTCYNIIPLYNSMKKKVLSDS-----EDEEKDADVPGTSTR--KRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALR------------------------FHKRNTITKRR------------------------------------------------------------------KKRNRSSSV-----------SSSAASSPERKKRILK---PQLKSE------------------------------------------------------SSTSAFSTPTRSIPPRHN-------------AAQINGKTESSSVVRTR-----SNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKTILENSVKHSKALNT---------------------------------------------------------------------------------------------------------LSSPGQSSFSHGTRNNSAKENMEKEKPVKRKMKSSVLPKASTLSKSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGR----------------------------------KPKVEVNTNSGEIIHKKRGRKPKKLQYAK-PEDLEQNNVHPIRDEVLPSSTCNFLSETNNVKED--LLQKKNRGGRKPKRKMKTQKLDADLLVPASVKVLR-----------------------RSNRKKIDDPIDEE------EEFEELKG----SEPHMRTRN------QGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PE61-1", "uniprot_id": "A0A8M9PE61_DANRE", "id": "A0A8M9PE61-1", "name": "PH-interacting protein", "aln": "-MAAERKHVAQLKSELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRIDWTGKEHPGSYENLVKLYRHISPDHLLQVCERVSPLLEREVPASVPGVNSLLGTGRQSVLRTNKSCKHVVWKGSALAALHCGRPPEPPVIFGSPPNIAETIHSRRLNGSYRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASITSLQFSPLCSGNKRFLSSTGADGTICFWQWDAR---TLKFGQRPSKFIERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEVFVLEPHPFDSRVLFSAGHDGNAIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSS-SRYDKIADQMFFHTDYRPLIRDAHNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENCREEQLIPQMGLTSS---------GLNQVVSQQAAEG-----------------SSPLDSMIQRLQQEQDQR------LGSDSR------------ANRGSVSSPTEVT----SPPNVGLRRSGQIEGVRQMHSNAPRSEIATERD--------LVAWSRRVLVPELSLAIACKQEIWRTAKGEEEINIYRSERRRR--------SLHSQYHR-----ENRHAIENAAEEG--RRHQGN----QHNYHTRLAVEETSRQSEPNEEEHSASEGETEVRPPSRESSDEEREEKEPWPDENSSSSDYSSDYSDWTADA-GINLEPPKKTSVKKKKKKNASSSEED---GEKKKDSKKERRKEKPDKDG-ALPKKKKPKEKRKR---IPELQNQGLTLEEWLPSNWITDTMPRRCPFTPQMGDEVYYFRQGHEAYVEMAKKNKIFSINPKKQPWHKLELREQELLKIVGIKYEVGLPTLCCLKLAFLDPDSGKLTGGSFSIKYHDMPDVIDFLVLRQQFDNARQRNWMIGDRFRAVIDDAWWFGTIESQEPYQAEYPDSLFQCYNVCWDNGDTEKMSPWDMEEVPDEVVFPEELGLSMALTQDEQKALLYKPLDGEWGSRTRNQECERIIRGINQLCTLDVAKPFELPVDLQAYPTYCTVVAYVTDLSTIRQRLENRFYRRMSSLMWEVRYIEHNAQTFNEPGAFIVRTAKFVSDLMLQFIK--------DQSCTDIIPLYNSMKKTAFSDSSDDEDEDEDEEHEAPCTSNRNKKRQQQQPMLRSLRSKPSSDPQAWKERCRELLELIFQCEDSEPFRQPVDLDEYPDYLDIVDTPMDFGTVLNRLLAGEYDTPMDLCKDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHISSILTDFKAAQS------------------------LHSERLTRQRLHTDRLTR--------------------------------------------------------QSVKKRRRRSSS-----------HSSSASSPERKRRVSSRAPPRLDSA------------------------------------------------------APPTPAG-PSRAPSLRQT-------------HPQINGKAETPVVPGRT-----RSSARFGSPITDVAPAQSAPPPLVESSSS------RVLRTQNPHSTAVSR---------------------------------------------------------------------------------------------------------ENESSAVPPSNGG---GARE-------SRRKLRTPVKLTPGPVDHSSPPQN------------SLHLNGHSQVTVGMVRRGRGRPRL-------------------------------DTQIETPVDTPPPPLPKTSSKKKERKSKKDTESPRRNFSH---EEELMLPTGDDGGASSTAQDS--NLSDSGEYPKARGRPRITKTIDTP--APPSPKTLR-----------------------RSSRRGNEEITPHTSGSAQSEEPEVYIGEDGSSKGQMKTRN------QGRRTAFYNEEDSEEEQRQLLFEDASITFGTSSKGRVRKLTEKAKANLIGW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC96-1", "uniprot_id": "Q9VC96_DROME", "id": "Q9VC96-1", "name": "", "aln": "METRQPSSGDDLKPELYFLISKFLAAGPLEETAKVLIRELEEKKVLPRRLDWQGNEHEQTFEELERKYKHIGANHLLEICSRLGPLVDRELPPSVPGINSLLGTGRQNLLRTKETVYCHRSLRDYCTRLNGVSLPDS-VLTKPTHNLDRVLTGREHGGEVRRKLLVPTDLYRRTKLLRRTVGHLSSVYCVLFDRTGRYIITGADDLLIKIWSAADGRLLATLRGASSEITDIAINLDNTMLAAGSLDHILRVWDMQTTSPIAVLSAHTGMITSVNFCPSPRSDLKYLVTTSTDGSIAFWQYSTPRGQKITFAPKPTQYHEKLRPGQAQMMCTTFSPGGIFLAAGSADHHVRVYMMGEDGPKRILETEAYTDAVDSVQWSHRGLRFISGSKDGTAHIWTFESQQWKSSKLCMTERLAS----CPEPEEGKRLKVTMVAWDASDRYVITAVNDFTIKIWDSKSAKLHRVLRGHKDELYVLESNPRDEHVLLSAGHDGQVFLWDIEQGVCVANFLNDIDGQGHGSVFDAKWSPDGTMIAATDSHGHILIFGLGVCIEKYKMLPTELFFHTDFRPLLRDAQHHVVDEQTQIMPHLMPPPFLVDADGNPHPSRFQRFVPGRESCSLDQLIPNLTVGVDGVVIDDGGAGGDAVVAAAPAEAPPAALPPAAAGGPQGANYSHIDRMIAALANRQSVNVNANDANPTNGNQSFERLTNRQMPDSNGRQSSRGNVLGSRLSTPRQGWGAAAAAPVEDQAGPSQPPAEPAAEPGQAQVQQALPLKFIRRTYVRPMKYPQLQNLKQTIYSAGQFEKQEYKREMRRRPIMINTASAASSQQPGSVGRPRNTRGNGGGARAGRRRGPQPAGGQPQPAYRTRAVRDQEPEHYDEVAPPPEEEE-EDVSSNSSGDTSYSN--VEENLEDSSDESETDSSDYSDWVADTPGPNLEPPKRSKRKPLSRRPRSSDDSS-----------------DDERAGRSRGGQVTARKVGRKTVLFPPTDANGEIPELYRPAEWLSEVIPRKAPYYPQMGDEVVYFRQGHAKYLDAVRLKKVYKLSHSSEPWNFHTLRDHELVRVIGIKYEIRPPRLCCLKLAIID-EEGNMTGTTFKIKYHDMPDVLDFLVLRQTFDLAVQRNWSIGDRFRCMIVDGWWMGQIESRHALSADFPDSSFMCFRVRWDNGEYEFMSPWDMEPID-QQRVPDEVGGAVPVLPEEIRATLYQPKSEEWHRGDRDGTCRRIINGLEQVMRLSIAEHFLAPVDLNIYPDYAYLIEYPIDLTTIKSRFENHFYRRITSAQFDVRYLATNAEQYNRRHAIIVKHSRIVTDLCLRIIR--------EPDEIDVAAVYHQLADVYHSSESENEVDSDVVPSTSTGPTTSAAAAAARQRVSSARRSTRIHSEGDWRADCRQLLDLMWARTDSAPFREPVDTIDFPDYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNKRSRIYAMTLRLSALFESHIKTVVTSWKAALRRANKNKSGSSGGGRGGSSSSPNKRVKKERSTRRNQKPTAAARRLPVANSSEDEDEEDDDDDDDDDDEEEASTRGRSRRRNGVAVSASSSGSNRVTSSSAAQQRRGKSSSSEEEEEEETSAQATSDASSDEEERAQSNDSSPQQTRTRRARQRQRLSDDSNINDSEDSYNPNEGRGSRRRPGAARPSSNRQTNGHSSKRRRLNKSPANAAPGPSLPRRTRRIAGSSAEEAASHSQHDESTQDSQIGRRKGRSASSRSIGNGPSTSAAAAANSSLESPSRNTRANGTRTSSHLGAENDHSYHLPVRNGRIIESDTDSPVIRPTRQSAKRALMDWGRGSDIEEEEEEEEEDSEEAEEILPTPTKDDLPSTSRAALAQAAAGPSRQLRTNRNTVVRPAQSDDDDDDDSDNEPLANNQQKNYQSPAKSSSTATVAPHPLSLRRRLASPPERNTHMTRSHATSTTSSAAASRAEQQPAVSTHDHNYLGNVNSSRAPRRILSRHQRNADELDTSLDVLENSRLLSAIANHRRPTSTTNSNSASNVVTRRLRGRASQANSHDEDHEEEEAAASDEGTDGGSSSQSYEDEDEDSDSEDNQPLTSYVSPSNGRPRRKAKTSSSSATTQERPLRRTRRPPSNNSIANDNDDDDDYVVPRSRRANRGGNQRAGRNQKRPRYNEQSEEEEAAAGYSHRSKRIRNGDAHASSQERSQASTERDQEEEEDGTSVDSEEQQVNVSSRGRVRKPSAKARGIFKE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :*:.******::** ** :::*:.****: :*::**:* ** *:** ::::* : *:*:..:***::* *:.**:::*:* ****:::***:***.:***::: . : *: *:. * .. .: .: .*. .*. * **** :*:: *: :* :********* ****** *:**:** *:***:: **:******* ::**:*:*:* :**::**** *:::*** ::* :*:***..*:. ***::*.* .. ::* :*.:**:*.** :.: .:.: :*::: *: *** .**:*::**.**:***:**:** :*** :* . *::* * * :** ***:*:*: . **:***:****:** :: ::*:* * *: : .. :: .::******** * ****.*::*:*:*:* :.:* :** **:**::***.:* * :**:******:.::**: :** : .::* *:*****:***.* **** :*.******::***:* . .:*. :. ::***:*:***:***::.*:***** ***********.******.*:**:*****.* :****:: : . * : *:: . : * :* ** * :.*. . . .. ..* ** :* *.*. * :. * .. * :* *:* . : : **. * :. . : : *: * : *: * :*: : :. * : * * *:** . :: .. : . .: * * :* .: :. .. ..*. *******.**: * **:***: : .: **.:.. . :: * : ..:: :: . :* * : *: *:::.:**:.*: ******* ****** *:: .: ::::.:. ..:**: **::**::::*****: * *******::* : *::** :*.:********:******* ** * * * ******.:* *.**:* ***:.. . ::*** * *:.* ****: * ******* : : .*:*:* ::.: * :: :*:* . ** *: *.**: *::*: *.:*. * ****: ** *. :: * **:**:.*:**:****.:* ::***: *:. :*. : **: :::*:** *::*: : :: .:*:.: . *.. :.: . .:. :* . . *: *.:**:*:: ** ***:*** ::*** :*: ****: ** : * .*:*: *:::.*******.* * *...*:****:*:*****:**.**.::::.:*:* .:... :. ::* : ** :* *** *.:: . *: :. . .. . *:. .* : ..: . : .. : ..:.:: . .: : * . ** : . . .: :*:: :. .. :. :: :.*. *. * . : : . : . *. . . : . . . ::. . . * * . .: . : * *:.* : . *: * . *. : ** . .*: .* *.***: .:. . ...**:***** : **:. : ", "identical_positions": 596, "similar_positions": 572, "identity": "26.28%" }, { "cls_id": "homologset.agr.MGI:1932407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZKE7-1", "uniprot_id": "A0A8I5ZKE7_RAT", "id": "A0A8I5ZKE7-1", "name": "CUGBP Elav-like family member 4", "aln": "MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAI-PFGAYGAYAQALMQQQAALMASVAQG-----GYLNPMAAFAAAQMQQMAALNMNGLAAAPMTP--TSGGSTPPGITAPAVPSIPSPIGVNG-FT-GLPP-QANGQPAAEAVFANGIHPYP-------------------------------------AQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQRE-----------GPEGCNLLIYHLPQEFGDAELMQMFLPFG--------------------FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSY6-1", "uniprot_id": "CELF4_MOUSE", "id": "Q7TSY6-1", "name": "CUGBP Elav-like family member 4", "aln": "MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAI-PFGAYGAYAQALMQQQAALMASVAQG-----GYLNPMAAFAAAQMQQMAALNMNGLAAAPMTP--TSGGSTPPGITAPAVPSIPSPIGVNG-FT-GLPP-QANGQPAAEAVFANGIHPYP-------------------------------------AQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQRE-----------GPEGCNLLIYHLPQEFGDAELMQMFLPFG--------------------FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZC1-1", "uniprot_id": "CELF4_HUMAN", "id": "Q9BZC1-1", "name": "CUGBP Elav-like family member 4", "aln": "MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAI-PFGAYGAYAQALMQQQAALMASVAQG-----GYLNPMAAFAAAQMQQMAALNMNGLAAAPMTP--TSGGSTPPGITAPAVPSIPSPIGVNG-FT-GLPP-QANGQPAAEAVFANGIHPYP-------------------------------------AQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQRE-----------GPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGV1-1", "uniprot_id": "CELF4_DANRE", "id": "Q6DGV1-1", "name": "CUGBP Elav-like family member 4", "aln": "----MATLTNGQVDAAVHG--GAASTNGLVNGIS-HTHSPASCATIPMKDHDAIKLFIGQIPRNLDEKDLRPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCARESALKAQTALHEQKTLPGMNRPIQVKPADSESRG----------EDRKLFVGMLNKQQCEDDVRRLFESFGSIEECTILRGPDGNSKGCAFVKYSTHAEAQAAISALHGSQTMPGASSSLVVKFADTDKERTIRRMQQMAGQMGIFNPMAL-QFGAYGAYAQ--VQQQAALMASVGQG-----GYLSPMAAFAAAQMQHMATIN--GLPGAPMTP--TSGGSTPPGITAPTVTSIPSPISVNG-FT-GLPPPQANGQAPAEAMFTNGIHPYPVLQEVVFREDSEKGGLGVAQRSCFGVQGSCFLSSLSEAQSPTAADPLQQAYAGVQQYA---AFPAAYGQISQAFPQPPPIIPQQQRE-----------GPEGCNLFIYHLPQEFGDGELMQMFLPFGNVISSKVFVDRATNQSKCFGFVSFDNPGSAQAAIQSMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q6L8-1", "uniprot_id": "A0A6M3Q6L8_DROME", "id": "A0A6M3Q6L8-1", "name": "", "aln": "---------------------------------------------------------------------MVHIIELVG-------------------------------QPKVEFAQQVT---MNRALQLKPAENESRS--------EHLDRKLFVGMLSKQQTEDDVRQIFHPFGTIEECTILRGPDGASKGCAFVKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRMQQMAGHMNLLNPFVFNQFSPYGAYAQ--QQQQAALMAAAATAPGSAAAYMNPMAALATQIPHGLNGTGQPPSLPSPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVFTNGIPQTAFPGHPLHLTIPPQGLPNGD-------------------------------------------AATLQHAFPGLPPFPG-VAFPAVYGQFPQALPPPLAAVAPTQREDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPYXQSEFLKRNSQQPTGATTSATGALPTTTAFSAATPTSAVTSVSATVTTTAHYNNLGSSFRPTLPLPTESSNHNAHIPYTFASWRSGTYCYRNHNNNSENYSDNNNNHRNVPDSQSQNDTSSNTNCSKVELVERLFMWQQQKRKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* .* :.: : :* * ***.:*:***:.***. *********.*** *****::*..**.************ ********:.:: ***:**. *****************:***:*** :********:*.::**:.: *..****** ********:.. . .*:.****:*: : : . :* * . *..** * .. :..: .:. ..:* ** *:* *:. :: .:*: * .**:*:.*: :. *:**.***:.**:* * . :. *** *******:**********.********** *******.***:***:*********************.*** ", "identical_positions": 209, "similar_positions": 96, "identity": "29.48%" }, { "cls_id": "homologset.agr.MGI:1932410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQ14-1", "uniprot_id": "IL23A_MOUSE", "id": "Q9EQ14-1", "name": "Interleukin-23 subunit alpha", "aln": "MLDCRAVIMLWLLPWVTQGLAVPRSSSPDWAQCQQLSRNLCMLAWNAHAPAGHMNLLREEEDEETKNNVPRIQCEDGCDPQGLKDNSQFCLQRIRQGLAFYKHLLDSDIFKGEPALLPDSPMEQLHTSLLGLSQLLQPEDHPRETQQMPSLSSSQQWQRPLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Z84-1", "uniprot_id": "IL23A_RAT", "id": "Q91Z84-1", "name": "Interleukin-23 subunit alpha", "aln": "MLDCRAIILLWLLPWATQGLAVPRSSSPDWAQCQQLSRNLCTLAWSAHTPVGQMDLLREEGEEETKSDVPRIQCGDGCDPQGLKDNSQFCLQRIRQGLVFYKHLLDSDIFTGEPSLLPDSPVDQLHTSLLGLSQLLQPEDHHWETQQMPRLSPSQQWQRSLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPF7-1", "uniprot_id": "IL23A_HUMAN", "id": "Q9NPF7-1", "name": "Interleukin-23 subunit alpha", "aln": "MLGSRAVMLLLLLPWTAQGRAVPGGSSPAWTQCQQLSQKLCTLAWSAHPLVGHMD-LREEGDEETTNDVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSPVGQLHASLLGLSQLLQPEGHHWETQQIPSLSPSQPWQRLLLRFKILRSLQAFVAVAARVFAHGAATLSP------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..**:::* ****.:** *** .*** *:******::** ***.**. .*:*: **** :***..:**:*** ********:**********:*** **::**.****.***:******: ***:************.* ****:* **.** *** *** *********:*:************: ", "identical_positions": 136, "similar_positions": 36, "identity": "69.39%" }, { "cls_id": "homologset.agr.MGI:1932411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHE4-1", "uniprot_id": "TM108_MOUSE", "id": "Q8BHE4-1", "name": "Transmembrane protein 108", "aln": "--------------------------------MKRSLQALYCQLLSFLLTLALTKALVLAVHEPSPRESLQTLPSGSPPGTMVTAPHSPTRLSSVLTLNPTPDGPSSQAAATLETTVSHPEGHPPTDTTSTVMGTAAVPHPESPLPTGSPPAAMTTTPSHSESLPPGD-ATPTTTLPTKPAGTTSRPTVAP-RATTRRPPRPPGSSRKGAGGSTRTLTPVPGGHLARKESQRGRNQSSAHLGPKRPLGKIFQIYKGNFTGSAEPDPSALTPRTPLGGYFSSTQPQTVSPATAPRSTSRVPPTTSLVPVKDKPGFIRSNQGSGPILTSPGGEPAATAATGAPASTQPAPVPSQSP-HGDVQDSASHSDSWLAVTPDTDRPTSASSGVFTAATGPTQAAFDATVSAPSPGIPQGPSATPQAPTRPSGVSESTVSPAEEEAEASPTTTDRGPRPLSTVLSTATGNFLNRLVPAGTWKPGTVANISHVAEGDKPQHRATICLSKMDIAWVIVAISVPISSCSVLLTVCCMRRKKKTANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GI14-1", "uniprot_id": "A0A8I6GI14_RAT", "id": "A0A8I6GI14-1", "name": "", "aln": "MQLRQEKRMTEVSETVFWEAVPSGVMDLISLAVEPVISGHFWKPPGFLLTLALTKALVLAVQGPSPRESLQTLPSGSPPGTMVTATHSPTRLSSVMTLSPKPDGRSSQAAATMETTVSHPEGHPPTDTVSTVMVTAAVPHPESPLPTGSPPAAMATTSSHSESRPPGDDAPAATTLPTKPAGTTTRPTVSP-RVPTRRPPRPPGSSRKGTGGSSRTFPLVPGGHSARKESQRGRNQSSTHLGPKRPLGKIFQIYKGNFTGSVEPDPSALTPRTPLGGYFSSTQPQTVSPATGPRSTSWVPPTTSLVPATDKPDLTRANQGSGPTFTSPGGEPDATAASGAPDSTQPAPVPSRSP-HGDVQDSSSHSDSWLAVTPDTDRPTSASSRVFTAATGPTQAAFDASVSAPPPGIPQGPSATPPAPAWPSGVSESIVSPAKEEAEASPTTTDRGPRPLSTVPSTATGNFLNRLVPAGTWKPGTVANISHVAEGDKPQHRATICLSKMDIAWVILAISVPISSCSVLLTVCCMRRKKKTANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXF1-1", "uniprot_id": "TM108_HUMAN", "id": "Q6UXF1-1", "name": "Transmembrane protein 108", "aln": "--------------------------------MKRSLQALYCQLLSFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQ--AAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPISSCSVLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSEPRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAE6-1", "uniprot_id": "E7FAE6_DANRE", "id": "E7FAE6-1", "name": "", "aln": "-MSRFCWKQEDSDYSPLENHEHCGGGAGPHDTMKRSLQVLPHQLLSILLILFVPAGLVFSTEELHPSQ---------PPRDLVSMSTSSRTLSPGLLSWQEGSSTGNLHNQALAS-------------LEAIRRPTAVDFFQTPKTTVPSAIVQTTTVGVHHFAPREQ------AQPGIPLNKAEVPELTPGSIFSRTNSKVFSTRTQDQNFSTNTDKPSTISRKPVNQFEPSG------------LLRTNQISTPGLVSGQRATNSGSGHSFVSGTEHDVADTEKMSKPIDPIQHQSSPSSFSLFKAHRSQNVNKVSAQHTITLRSLSITENPTLPLDTVGGALAQTYIQSPP---------------PALAPPSNHISTESSNTVEVGTNGTTNMTVEFLISPTNATDVLNSTDSLRPAAND-------------------------SDMSEVPSTDSGSFMNRQVPATTQGPWGSGNQSGPALG-PPHEKNTICLDKMDIVWLVLAISVPVSTCSVLLTVCCMRKKKKSASQENNLSYWNDAITMDYFTRHAVELPREIQSLEAEEQ---ETCLPPNGDYSDSGVVLVNPFCQETLFINRDKASDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. : .:** * :. .*.:: . * : ** :*: . *. :. : .. . .: : .:: ..:. . ::. .* ... . :** . . * : * . : * :* :* .: .: :. . *:.. . .: :: : . * : ** . .:... .. * . .:.:.:: . * . . *.: ** . . .. : : * . .* . .: .. . . . * :::* :.: : ** .. ..*. * : :*. . *: . *: . :* * ** :*.*:** *** * * .* * * * *:.: ****.****.*:::*****:*:**********::***:*. ********::******.**************:.*: *. *.**** *:*:************:..*:.*:*", "identical_positions": 136, "similar_positions": 162, "identity": "22.33%" }, { "cls_id": "homologset.agr.MGI:1932466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8T6-1", "uniprot_id": "D3Z8T6_RAT", "id": "D3Z8T6-1", "name": "", "aln": "MKTGCAAGSPGNEWVFFSSDERSTRSRKTMSNGALQRSAVLSA---LVLLRAVTGFSGDGKAIWDKKQYVSPVNPGQLFLYDTFPKNFSWGVGTGAFQVEGSWKADGRGPSIWDRYVDSHLRGVNST---DRSTDSYVFLEKDLLALDFLGVSFYQFSISWPRLFPNGTVAAVNAKGLQYYRALLDSLVLRNIEPIVTLYHWDLPLTLQEEYGGWKNATMIDLFNDYATYCFQTFGDRVKYWITIHNPYLVAWHGFGTGMHAPGEKGNLTAVYTVGHNLIKAHSKVWHNYDKNFRPHQKGWLSITLGSHWIEPNR-TENMEDVINCQHSMSSVLGWFANPIHG-DGDYPEFMKTS-------------SVIPEFSEAEKEEVRGTADFFAFSFGPNNFRPSNTVVKMGQN------------------------------VSLNLRQVLNWIKLEYDNPRILISENGWFTDSYIKTEDTTAIYMMKNFLNQVLQAIKFDEIQVFGYTAWTLLDGFEWQDAYTTRRGLFYVDFNSEQKERKPKSSAHYYKQIIQDNGFPLQESTPDMKGQFPCDFSWGVTESVLKPEFTVSSPQFTDPHLYVWNVTGNRLLYRVEGVRLKTRPSQCTDYVSIKKRVEMLAKMKVTHYQFALDWTSILPTGNLSKINRQVLRYYRCVVSEGLKLGISPMVTLYHPTH--SHLGLPMPLLSSGGWLNTNTAKAFQDYAGLCFQELGDLVKLWITINEPNRLSDMYNRTSNDTYRAAHNLMIAHAQVWHLYDRQYRPVQHGAVSLSLHSDWAEPANPYVESHWKAAERFLQFEIAWFADPLFKTGDYPLAMKEYIASKKQRGLSSSVLPRFTLKESRLVKGTIDFYALNHFTTRFVIHKQLNTNRSVADRDVQFLQDITRLSSPSRLAVTPWGMRKLLGWIRRNYRD-MDIYVTANGIDDLALEDDQIRKYYLEKYVQEALKAYLIDKVKIKGYYAFKLTEEKSKPRFGFFTS---DFKAKSSVQFYSKLISSSGFSSENRSPACGQPPEDTECAICSFLTQKKPLIFFGCCFIS-----TLAALLSITIFHHRKRRKFQKARNLQNIPLKKGHSRVFS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N32-1", "uniprot_id": "KLOTB_MOUSE", "id": "Q99N32-1", "name": "Beta-klotho", "aln": "MKTGCAAGSPGNEWIFFSSDERNTRSRKTMSNRALQRSAVLSA---FVLLRAVTGFSGDGKAIWDKKQYVSPVNPSQLFLYDTFPKNFSWGVGTGAFQVEGSWKTDGRGPSIWDRYVYSHLRGVNGT---DRSTDSYIFLEKDLLALDFLGVSFYQFSISWPRLFPNGTVAAVNAQGLRYYRALLDSLVLRNIEPIVTLYHWDLPLTLQEEYGGWKNATMIDLFNDYATYCFQTFGDRVKYWITIHNPYLVAWHGFGTGMHAPGEKGNLTAVYTVGHNLIKAHSKVWHNYDKNFRPHQKGWLSITLGSHWIEPNR-TDNMEDVINCQHSMSSVLGWFANPIHG-DGDYPEFMKTG-------------AMIPEFSEAEKEEVRGTADFFAFSFGPNNFRPSNTVVKMGQN------------------------------VSLNLRQVLNWIKLEYDDPQILISENGWFTDSYIKTEDTTAIYMMKNFLNQVLQAIKFDEIRVFGYTAWTLLDGFEWQDAYTTRRGLFYVDFNSEQKERKPKSSAHYYKQIIQDNGFPLKESTPDMKGRFPCDFSWGVTESVLKPEFTVSSPQFTDPHLYVWNVTGNRLLYRVEGVRLKTRPSQCTDYVSIKKRVEMLAKMKVTHYQFALDWTSILPTGNLSKVNRQVLRYYRCVVSEGLKLGVFPMVTLYHPTH--SHLGLPLPLLSSGGWLNMNTAKAFQDYAELCFRELGDLVKLWITINEPNRLSDMYNRTSNDTYRAAHNLMIAHAQVWHLYDRQYRPVQHGAVSLSLHCDWAEPANPFVDSHWKAAERFLQFEIAWFADPLFKTGDYPSVMKEYIASKNQRGLSSSVLPRFTAKESRLVKGTVDFYALNHFTTRFVIHKQLNTNRSVADRDVQFLQDITRLSSPSRLAVTPWGVRKLLAWIRRNYRD-RDIYITANGIDDLALEDDQIRKYYLEKYVQEALKAYLIDKVKIKGYYAFKLTEEKSKPRFGFFTS---DFRAKSSVQFYSKLISSSGLPAENRSPACGQPAEDTDCTICSFLVEKKPLIFFGCCFIS-----TLAVLLSITVFHHQKRRKFQKARNLQNIPLKKGHSRVFS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Z14-1", "uniprot_id": "KLOTB_HUMAN", "id": "Q86Z14-1", "name": "Beta-klotho", "aln": "MKPGCAAGSPGNEWIFFSTDEITTRYRNTMSNGGLQRSVILSA---LILLRAVTGFSGDGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSST---NGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNR-SENTMDIFKCQQSMVSVLGWFANPIHG-DGDYPEGMRKKLF-----------SVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQN------------------------------VSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQGQFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTH--AHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGD-MDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTS---DFKAKSSIQFYNKVISSRGFPFENSSSRCSQTQENTECTVCLFLVQKKPLIFLGCCFFS-----TLVLLLSIAIFQRQKRRKFWKAKNLQHIPLKKGK-RVVS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IX01-1", "uniprot_id": "A0A0R4IX01_DANRE", "id": "A0A0R4IX01-1", "name": "", "aln": "-------------MCFLSS----------VSFALLLISVCPSE---SLLQ-------GDSSSVWLQRLNGTHQQTG------VFPRGFLWGIGSSAFPTEGSWDADGKGASIWDHFTLQSPAGAS--------SDSYIQWEEDLKAVQFLGVDFYSFSLSWPRLFPD-LTLNPNPAGVEHYRRLIRKLKELNVEPVVTLFHWDLPQVLQERLGGWLNSSMVGVFADYAEFCFRTFGDEVRFWITMHNPFLVAVQGYGTGAHAPGVKGERGDPFIAAHNLIRAHAKAYHVYDKLFRARQNGKVSISLGSHWVEPLHGQATPTNLELCQKSMEAVIGWFAEPIYG-SGDYPESLKSANR-----------GVIPEFSAAERLWVRGSADFFSVAFGPETLRVSRGLARFGQT------------------------------VALELRSVLVWVQQAYGDPLVLVAESGWFSDASVGVEDTLAIYLNKRFILQVMQAVSVDAVRVFGYTAWSLLDGYEWNQGFSVRRGLFYIDFSQSERRRVPKTSAHFYRQTVRDNGFPDTD-TKHIQARFPCHFQFGVSDSILQVRLHPFSPQFTDPHLYRWNFSGDGSLKPVNGIILHTRPAQCTDFLFIQRHLFLLGVTGSTHYRFSLDWTQLSP----SAGHPETLRFYRCVFSELQRRGIQPVVTLYHPSYRSSSLGLPEALHANGGWRNASTVDAFVRYATFCYREFGALVHMWITINEPNRLTDAYSGSADDRRVVARHLLLAHAKAWRAYDVYFRKQQGATVSLALHADWVEPANPFLESHKNAQQHFLLFELGRFIDPLYNQ-----------------ESSSSTLIGWSDDEREELRGALDFIALNHFTTRLVS-PWAHLKASTPDHGCSLMNDVNWQTSQMGQALVPWGLRRMLGWVKNRYGNRLPIIITASGVDDQAAYHDQLRQSYIRDYLQEALKARELDGVNLRGFYIWKLQDHHD-LQFGLFSSAAHHSRPKASASLYRDIISHRGFIS-SGDPCQSADEDGTSCEICAHIAENKPLLFFSVCVFVSVCMICVLIILSVLRKRRRKRRKTLSVPQRVPVPQRFPMMRVTHRLRH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV98-1", "uniprot_id": "Q9VV98_DROME", "id": "Q9VV98-1", "name": "Cytosolic beta-glucosidase", "aln": "------------------------------MMQIILPLFVLTASCLG-------------SPVSQTRR---------------FPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHPEKIVDRSNGDVSADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQELGG-WTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYNYPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRD-PNSAEDREASERAMQFYVGWFGHPIFSKHGNYPKVMIERIRNLSKEQGFGARSRLPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSDRG--GLEDYARVDYYNLYLSAVLDAMEDGAN-ISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQRTRTPKISARVFAQLCKTN---------------------------------------TIDWSYRPKLDEEQQLVAMAQLPAEARTSGASGAVSWSLMGILLLALLR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: . **..* **:*:.: **.*. *.:* **** :*** :.*: :. : *. * **:****::*. .. *:.:* *: * *: *:**::**:** *** * * * :: :* *** :. :**.*: * *:::*: *. :*:*.. **. : : .***::**::. * * *:.:* * :.*:*.: * ** . : .:::* :***..**.. *:**: : . :* *: * :**::***.. ...: . . *: . : . * *:: *. * ::::*.* . ** : : :: *::*: . : ** **:*:*.:**: .:: : **:::**.. :: * ** **: : * : * : * : : * : : .:*.: .:. : . :* ", "identical_positions": 127, "similar_positions": 156, "identity": "11.45%" }, { "cls_id": "homologset.agr.MGI:1932475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96PQ1-1", "uniprot_id": "SIG12_HUMAN", "id": "Q96PQ1-1", "name": "Sialic acid-binding Ig-like lectin 12", "aln": "MLLLLLLLPPLLCGRVGAKEQK----DYLLTMQKS-VTVQEGLCVSVLCSFSYPQNGWT---ASDP-VHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLG-DPQNKDCTLSIRDTRESDAGTYVFCVERGNMKW------NYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGAS-----------VSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN-------------------------ISYPPQNLTMTVFQGDGTASTTLRNGSALSVL-----------------------------------------EGQSLHLVCAVD---SNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKK---SARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATP-----SPEEGEIQYASLSFHKAR--PQYPQEQEAIGYEYSEINIPK-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y286-1", "uniprot_id": "SIGL7_HUMAN", "id": "Q9Y286-1", "name": "Sialic acid-binding Ig-like lectin 7", "aln": "--MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSS-VTVQEGMCVHVRCSFSYPVDSQT---DSDP-VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLG-DPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKW------NYKYDQLSVN-------------------------------------------------------------------------------------------------------------------------------VTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTS-----------VSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLN-------------------------VSYPPQNLTVTVFQGEGTASTALGNSSSLSVL-----------------------------------------EGQSLRLVCAVD---SNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKK---SARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHG--LAAHS-----SGEEREIQYAPLSFHKGE--PQDLSGQEATNNEYSEIKIPK-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y336-1", "uniprot_id": "SIGL9_HUMAN", "id": "Q9Y336-1", "name": "Sialic acid-binding Ig-like lectin 9", "aln": "---MLLLLLPLLWGRERAEGQT----SKLLTMQSS-VTVQEGLCVHVPCSFSYPSHGWI---YPGPVVHGYWFREGANTDQDAPVATNNPARAVWEETRDRFHLLG-DPHTKNCTLSIRDARRSDAGRYFFRMEKGSIKW------NYKHHRLSVN-------------------------------------------------------------------------------------------------------------------------------VTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWIGTS-----------VSPLDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLN-------------------------VSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLP-----------------------------------------EGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQSKAT------SGVTQGVVGGAGATALVFLSFCVIFVVVRSCRKK---SARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARS-----SVGEGELQYASLSFQMVK--PWDSRGQEATDTEYSEIKIHR-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NYZ4-1", "uniprot_id": "SIGL8_HUMAN", "id": "Q9NYZ4-1", "name": "Sialic acid-binding Ig-like lectin 8", "aln": "-MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQEL-VTVQEGLCVHVPCSFSYPQDGWT---DSDP-VHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLG-DIWSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLNYKTKQLSVF-------------------------------------------------------------------------------------------------------------------------------VTALTHRPDILILGTLESGHSRNLTCSVPWACKQGTPPMISWIGAS-----------VSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLD-------------------------VSYPPWNLTMTVFQGDATASTALGNGSSLSVL-----------------------------------------EGQSLRLVCAVN---SNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRSCRKK---SARPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVAPS-----SGEEGELHYATLSFHKVK--PQDPQGQEATDSEYSEIKIHKRETAETQACLRNHNPSSKEVRG---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M8J5-1", "uniprot_id": "F1M8J5_RAT", "id": "F1M8J5-1", "name": "", "aln": "----MLLLLLLLWGIKGVEGGAVALKGYTLNVERK-VVVQEGLCVLVPCNFSYPKFWQT---DSSP-VYGYWFRKKANTDIDAPVATNNPKRPAQERTQHRFFLPG-DQQKNDCSLNIREIKKKDAGTYFFRLERGKTKY------NYLWNMMTLD-------------------------------------------------------------------------------------------------------------------------------VTALTNT-LRILPETLEAGHPSNLTCSVPWDCEKRAPPVFSWNGTS-----------VSPLSTNTTGSSVLTIIPQPQDHGTNLTCQVTLPGTDVTTRMTIRLN-------------------------VSYAPKNLTVTVYQGADSVSTILKNGSSLQIS-----------------------------------------EGQSLRLICSAD---SYPPANLSWSWGNLTLCPPKLSKPGLLELFPMHLKHEGVYTCQAQHALGSQYISLNLSPQRSAT-----LSEMMMGTLMDSGVTALLFLSFCIILLAVRSCRRK---PARTAVVAPHP-----NALKVSVSQSPLVESHADDSSEPLPSTVEAAP-----SSTKEEIHYASLSFHEMK--PRNSWGQQGSTTEYSEIRLHK-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Y57-1", "uniprot_id": "SIG12_MOUSE", "id": "Q91Y57-1", "name": "Sialic acid-binding Ig-like lectin 12", "aln": "--MLLLLLLLLLWGIKGVEG-QNPQEVFTLNVERK-VVVQEGLCVLVPCNFSYLKKRLTDWTDSDP-VHGFWYREGTDRRKDSIVATNNPIRKAVKETRNRFFLLG-DPWRNDCSLNIREIRKKDAGLYFFRLERGKTKY------NYMWDKMTLV-------------------------------------------------------------------------------------------------------------------------------VTALTNTPQILLPETLEAGHPSNLTCSVPWDCGWTAPPIFSWTGTS-----------VSFLSTNTTGSSVLTITPQPQDHGTNLTCQVTLPGTNVSTRMTIRLN-------------------------VSYAPKNLTVTIYQGADSVSTILKNGSSLPIS-----------------------------------------EGQSLRLICSTD---SYPPANLSWSWDNLTLCPSKLSKPGLLELFPVHLKHGGVYTCQAQHALGSQHISLSLSPQSSAT-----LSEMMMGTFVGSGVTALLFLSVCILLLAVRSYRRK---PARPAVVAPHP-----DALKVSVSQNPLVESQADDSSEPLPSILEAAP-----SSTEEEIHYATLSFHEMK--PMNLWGQQDTTTEYSEIKFPQRTAWP--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T5V7-1", "uniprot_id": "A0AB32T5V7_DANRE", "id": "A0AB32T5V7-1", "name": "", "aln": "-MKIISLCTIIFMLVFNVLCEENADNGWNISFSPREVTAVKGLCAHISCTFTYP-------VAENPIQSVIWQSCVAKDKCNLIFQNNVEKNKLKKNELGHIKMLEPDLSKNNCSIILKDIKENEK-EYTFRIKAKQQYT--------FNPTVKIS----------------------------------------------------------------------------------------------------------------------------------IKDEPTLVVP-PLSEKVEVNLTCSAPFPCPETPPVITWWIKTKEENYIKLDNNKITQVHSEHVYYSYLTLIPTSDQHDGTVGCDVRYGNKKINTNNTLEVKYVQALQIVGENTLMEGDTLNLTCTFRSHPPASNPVWRFNGNTDNLNTQTSAGTLMIANVGKEHAGIYVCEMTYMNKTLNASITINITEVNILGENRLKKGDTLNLTCSFKN-HPQSSSNPVWSFNGDADKLKNQASAANLIIDNVTKEHAGIYACEMTYMKKTLNASITVDITGVLDFLLS--IPNIFTFVAGMAFSALIFSVILCCWVCCHRGKKQKVPTANPDAEINLETVQTDVAQNGTTEQTPLHEQPDGETPKTPATPTDGAEEDEALGTEAREVDYASIDYSLLKDKPPEEAETEPTDTDYAEIKKDRTKDWKDTEDPQDGDEQVETFDQKEMGAEEELYSQVPQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :: : .. *.. :*:*. : *.*:* .* * . . .* . :: : * ::*:: ::: : : * * :: . :.: :.. : .*. *****.*: * .* * :. :: . . * *:: * .:.*. .: *:* . :. ::.:. *:.* . .: ::* . ...:* : :*::*.* *: . . ..:. : . : . :. * : : . . ::*. : :.:. . . . :** * . : : ::: .*.. . : . :..* * * .. . . *:.**.:.: . * : :*:**. : ", "identical_positions": 54, "similar_positions": 146, "identity": "7.32%" }, { "cls_id": "homologset.agr.MGI:1932491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04118-1", "uniprot_id": "PRB3_HUMAN", "id": "Q04118-1", "name": "Basic salivary proline-rich protein 3", "aln": "MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPE---------------------GRRPQG-GNQPQRTPPPPGKPEGRPPQGGNQSQGPPPR-------------------PGKPEGPPPQGGNQSQ--GPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP--PPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPP-------PRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNKPQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPP---------------------------------PPGGNPQQPLPP-PAGKPQGPPPPPQGGRPHRPPQGQ-PPQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10163-1", "uniprot_id": "PRB4_HUMAN", "id": "P10163-1", "name": "Basic salivary proline-rich protein 4", "aln": "MLLILLSVALLALSSAESSSEDVSQEESLFLISGKPE---------------------GRRPQG-GNQPQRPPPPPGKPQGPPPQGGNQSQGPPPP-------------------PGKPEGRPPQGGNQSQ--GPPPHPGKPERPPPQGGNQSQGPPPHPGKPESRPPQGGHQSQGPPPTPGKPEGPPPQGGNQSQGT--PPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSHRPP-------PPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNK------------------------------------SRSARSP------PGKPQGPPQQEGNKPQGPPPPGKPQGPP---------------------------------PAGGNPQQPQAP-PAGKPQGPPPPPQGGRPPRPAQGQQPPQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04280-1", "uniprot_id": "PRP1_HUMAN", "id": "P04280-1", "name": "Basic salivary proline-rich protein 1", "aln": "MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQ---------------------GPSPQG-GNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ--GPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGD-KSQSPRSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGD-KSQSPR-------SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPQQGGNRPQGPPP-PGKPQGPPPQG-DKSRSPQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRPPQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02812-1", "uniprot_id": "PRB2_HUMAN", "id": "P02812-1", "name": "Basic salivary proline-rich protein 2", "aln": "MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQG-GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ--GPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGDNKSQSAR-------SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRPPQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04105-1", "uniprot_id": "Q04105_RAT", "id": "Q04105-1", "name": "", "aln": "MLVVLFTAVLLTLSYAQEA--ELQSLDQTPNQKPPPP---------------------GFPPRPPANGSQQGPPPQGGPQQKPPQ------------------------------PGKPQGPPPPGGPQ----QKPPQPG---------------------KPQGPPPPGG-------PQQKPPQ----PGNQQ-----GPPPPGGPQQKP-----------PQS----------------------------GKPQGPPPPGGPQQR-PPQ----PGN-------------------------------------------------------------QQSPPQGP-------QFGRPQGSF--------------------------------QSLGPQ-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PU38-1", "uniprot_id": "E9PU38_RAT", "id": "E9PU38-1", "name": "", "aln": "MLVVLFTAVLLTLSYAQEP--ELQSLDQTPNQKPPPP---------------------GFPPRPPANGSQQGPPPQGGPQQKPPQ------------------------------PGKPQGPPPPGGPQ----QKPPQPGNQQGPPPPGGPQQKPTQP--EKPQGPPPPGG-------PQQRTPQ----PGNQQ-----GPPPPGGPQQKP-----------PQPEKPQGPPPPGGPQQKP---------PQPGKPQDPPPPGGPQQR-PPQ----PGN-------------------------------------------------------------QQSPPQGP-------QLDRPQGSF--------------------------------QSLGPQ-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05143-1", "uniprot_id": "PRP2_MOUSE", "id": "P05143-1", "name": "Proline-rich protein 2", "aln": "MLVVLFTVALLALSSAQGPREELQNQIQIPNQRPPPS---------------------GSQPRPPVNGSQQGPPPPGGPQPRPPQGPPPPGGPQ---------------------PRPPQGPPPPGGPQPRPPQGPPPPGGPQPRPPQGPPPPGGPQP--RPPQGPPPPGG-------PQPRPPQGPPPPGGPQQRPPQGPPPPGGPQPRPPQG--PPPPAGPQPRPPQGPPPPAGPHLRPTQGPPPTGGPQQRYPQSPPPPGGPQPR-PPQGPPPPGGPHPRPTQGP---------------------------------PPTGPQPRPTQGPPPTGGPQQRPPQGPPPPGGP-QPRPPQGPP--------------------------------PPTGPQPRPTQGPHPTGGPQQTP--PLAGNPQGPPQGRPQGPQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*::..**:** *: ::.. . * * *: * .* *** * *: *** * *:* ** ** * ** ** *:. ** *. . *: *. * ** ** *: * * . *: *** ** * : ** * . * * * ***. . * : ", "identical_positions": 64, "similar_positions": 31, "identity": "14.58%" }, { "cls_id": "homologset.agr.MGI:1932515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERS4-1", "uniprot_id": "PKHA3_MOUSE", "id": "Q9ERS4-1", "name": "Pleckstrin homology domain-containing family A member 3", "aln": "---------MEGVLYKWTN-YLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHPADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTAKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHRDERHPSPSVENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLPHPDPLVSPVSPSPVQMMKRSASHPGSCSSERSSCSIKEPASALHRLPQRRRRTYSDTDSCNDVPPEDPERPLHCSGNTLNGDLASATIPEESRLMAKTQSE--EPLLPFS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZL55-1", "uniprot_id": "A0A8I5ZL55_RAT", "id": "A0A8I5ZL55-1", "name": "Sesquipedalian", "aln": "MNIHLLINPPSGLPCSVSLPGRTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTAKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDEDHSSPSVENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLPHPDPLVSPVSPSPVQMMKRSASHPGPCSSERSSCSIKEPASALHRLPQRRRRTYSDTDSCNDVPPEDPERPLHCSGNTLNGDLASAAIREESRLTAKTHSESEEPLPPFS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HB20-1", "uniprot_id": "PKHA3_HUMAN", "id": "Q9HB20-1", "name": "Pleckstrin homology domain-containing family A member 3", "aln": "---------MEGVLYKWTN-YLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: . : ******************************************.********************************************* **************************************:** *.***.*************************************** ********************.****.******* *****.*:****.*************.*:* ***:**:*** **********:* ***** **.:** :.* .** ", "identical_positions": 258, "similar_positions": 23, "identity": "83.23%" }, { "cls_id": "homologset.agr.MGI:1932535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIA9-1", "uniprot_id": "D3ZIA9_RAT", "id": "D3ZIA9-1", "name": "Zinc finger protein GLIS2", "aln": "MHSLDEPLDLKLSITKLRAAREKRERTLGVPRHHALH----RELGLVDD---SPTPGSPGSPPPGFLLNPKFPEKLDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPLPTAVDFQPLRYLDG--VPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKP-EQDARYCCHWEGCARHGRGFNASRYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQE--LLQLRPPPKPPLPTPDSGSYVSGAQIIIP-NPAALFGGPSLPGLP-----LPLAPGPLDLSALACGNGGG--GGGGMGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTSLERTERSRSRPSPDGLPLLPGTVLDLSTG-NSAASSPEALTPGWVVIPPGSVLLKPAVVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDL9-1", "uniprot_id": "GLIS2_MOUSE", "id": "Q8VDL9-1", "name": "Zinc finger protein GLIS2", "aln": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRHHALH----RELGLVDD---SPAPGSPGSPPPGFLLNPKFPEKVDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPECQGNGDLPPLPTAVDFQPLRYLDG--VPSSFQFFLPLGSGGALHLPASSFLPPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKP-EQDARYCCHWEGCARHGRGFNA-RYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQE--LLQLRPPPKPPLPTPDSGSYVSGAQIIIP-NPAALFGGPSLPGLP-----LPLPPGPLDLSALACGNGGG--GGGGIGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTPLERTERSRSRPSPDGLPLLPGTVLDLSTG-NSAASSPEVLTPGWVVIPPGSVLLKPAVVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE0-1", "uniprot_id": "GLIS2_HUMAN", "id": "Q9BZE0-1", "name": "Zinc finger protein GLIS2", "aln": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALH----RELGLVDD---SPTPGSPGSPPSGFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPLRYLDG--VPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFELLQDLVDHVNDYHVKP-EKDAGYCCHWEGCARHGRGFNA-RYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQE--LLQLRPPPKPPLPAPDGGPYVSGAQIIIP-NPAALFGGPGLPGLP-----LPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7D0-1", "uniprot_id": "A0ACD6B7D0_DANRE", "id": "A0ACD6B7D0-1", "name": "Zinc finger protein GLIS2", "aln": "MLSLDEPLDLKVPRGRI-SGRDRGARSPPTLSSSPIHGKGAGQLRMADDGTAVIVPASPASPHTGVLRS-------NSETPTPPAVDLSLSPSS--RNTACSPELS---NGSGSAPVFP--GDSAHIRYVEGGATSQAFQFFVPIGAGGGLHLPSSMFIRQPKDTRASPDLSADEQLACRWRKCHLLFDSLQDLVDHVNDFHVKP-EKDSGYCCHWEGCARKGRGFNA-RYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYICPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMVGCLKRYTDPSSLRKHIKAHGHFVAQEQGGGVGSLIKQSQIAGVGKDSELTYVSGAHIIIPSAAAALLGGHALQGLGGSLPLSPLSPRPLDLSTLGCPNSPT--AGLGGTPILSFSSSPLGLTKSPLLSPSFSSSTLGLPMLPILG-----SERRDHGKG----KIRGEEGEDE-------------------IHGGVLNLSTG-----ASHDPLS--WVVIPSGPVVLKPAVVN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K0S9-1", "uniprot_id": "GLIS2_DROME", "id": "Q7K0S9-1", "name": "Zinc finger protein GLIS2 homolog", "aln": "-------MDIIQKSIFNSGPHSRGIYEPPLGYFTPYN---------------TPPYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQHIRFPTPP-------ITPPRPIAGYGYRQR--------------------TQSVIMKARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNA-RYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIHLIASQP-LTLPSVPCLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNE---------PSDYSLKPKQDAEFSP--------SYWLGDRQHSYLHSEDFFVKMDVESPLDLRIHRI-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: . :.: . : :. * . * . : . .: :.... . . :: . * . * .. * .*. *.: .::.*.* .*. :*: *: *.:**.: *. . *. * *:*.** * ***** *****:* ****:****** *.***** ****** ***:***** *.:***:* ************** ::*** **: ** ************:*:. * : . . . :..* : . .:: . * .*.. : . * .. :: . *.* : : ", "identical_positions": 111, "similar_positions": 91, "identity": "20.44%" }, { "cls_id": "homologset.agr.MGI:1932544", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABE3-1", "uniprot_id": "D4ABE3_RAT", "id": "D4ABE3-1", "name": "[heparan sulfate]-glucosamine N-sulfotransferase", "aln": "-----------------MSFIMKPHRHF------------------------------------------QRTLIL-----------------------------------------------------------LAT------------------------------------FCMVSIVISAYYLYSGYKQESEVSGRASVVDCGDLQHIPSRLMEAKRTMISDAS-----------RTDPTVLVFVESQYSSLGQDIIMMLESIRFHYHTEIAPGKGDLPALTDNVKGKYILIIYENILKYINMDSWNRSLLDKYCIEYGVGIIGFHKTNEKTLQSFQSQGFPFSISGNLAVKDCCINPHSPLLRVTKSSKLDRGSLPGADWTVFQINHSTYQPVIFAKVKTPENLSPPISKHAF-YATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDALSFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRSQITNFTFNLGFSGKFYHTGTEEEDAGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLIEQMILNKKFALEHGIPTDMGYAVSPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPRELDKSIHGGELFFTVVLNPISIFMTHLSNYGNDRLGSYTFVNLANFVQTWTNLRLQTLPPAQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALCLFLIMHPSILSNSPSPKSFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTD-----------FLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPNAPWELRTLQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTAPATVMDEVQKFLGVSPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRAFLSSYYRDHNVELSKLLHRLG-QPLPSWLRQELQKVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQH7-1", "uniprot_id": "NDST3_MOUSE", "id": "Q9EQH7-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3", "aln": "-----------------MSFIMKPHRHF------------------------------------------QRTLIL-----------------------------------------------------------LAT------------------------------------FCMVSIIISAYYLYSGYKQESEVSGRASEVDCGDLQHIPSRLMEVRRTMISDAS-----------RTDPTVLVFVESQYSSLGQDIIMMLESIRFHYHTEIAPGKGDLPALTDNVKGKYVLIIYENILKYINMDSWNRSLLDKYCIEYGVGIIGFHKTSEKNLQSFQFRGFPFSISGNLAVKDCCINPHSPLLRVTKSSKLDRGSLPGTDWTVFQINHSTYQPVIFAKVKTPENLSPPISKHAF-YATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRTQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLIEQMILNKKFALEHGIPTDMGYAVSPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPRELDKSIHGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANFVQTWTNLRLQTLPPAQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALCLFLIMHPSILSNSPSPKSFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTD-----------FLFEKSANYFHSEDAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPNAPWELRTLQKRCLVPGWYANHIERWLVYFPPFQLLIIDGQHLRTTPATVMDEVQKFLGVSPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRAFLSSYYRDHNVELSKLLHRLG-QPLPSWLRQELQKVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95803-1", "uniprot_id": "NDST3_HUMAN", "id": "O95803-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3", "aln": "-----------------MSFIMKLHRHF------------------------------------------QRTVIL-----------------------------------------------------------LAT------------------------------------FCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHLPYQLMEVKAMKLFDAS-----------RTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKTPENLSPSISKGAF-YATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTD-----------FLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLG-QPLPSWLRQELQKVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3L1-1", "uniprot_id": "NDST_DROME", "id": "Q9V3L1-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase", "aln": "MTISGGNQHNNNANRKYEKLIKQPQMQFGSSVTGTQTDVDSCRDADADANAVRQDFSNFNKHFGNGHAITDRTMLLRLEDDVTTAAGIVTYKGKSNGNGNGNGNGSIGSISLDFNGSPTSSTSIGIASGSSSNTHLASGGGVGGIGGSEPAGWMCHCCNLIARRCFGINVRRCVLALLAITMVSIFYYTHYVDTGVFNG-LIQRDTHPAPIINCRMINSGGKHIRNASPAPDHRSEARLRIDPKVLVFVETTYSGLGRDIAELLVYNRIKYKIEVAG--KSLPVLTNLDKGRYGVIVFENLDKYLNMDKWNRELLDKYCREYSVGIVGFVSPSEETLVGAQLRDFPLFVNTNLRLRDASLNPLSSVLRLTRAGETAWGALPGDDWAVFQHNHSTYEPVEWAQRNTQEYPADSVGQVQLPLTTVLQDRGQLDGIQRVLFGSSLRFWLHRLVFLDALSYLSHGQLSLNLERMILVDIDDIFVGEKGTRLRPDDVRALIATQKNIAAMVPGFRFNLGFSGKYYHHGTREENLGDDFLLQNVQEFNWFSHMWKHQQPHLYDNLTLLMAEMHLNYAFAVDHNIPTDSGYSISPHHSGVYPAHELLYMAWKKVWNVKVTSTEEYPHLRPARLRRGFIHRNIMVLPRQTCGLFTHTMYIDRYPGGRDKLDESIQGGELFQTIVYNPINIFMTHMSNYGSDRLALYTFQSVIKFLQCWTNLKLASAPPVQLAEMYFRLHPEEVDPVWGNPCDDVRHKKIWSKTKNCDSLPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGDVIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNKCLGKSKGRQYPAMDERSAKLLQRYYLNHNTALVKLLKKLGSRPIPQWLKDDLSTGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* : : :* :**::* **: :.:::* : : : *: * : . .. * : :::: : :** * **.******: **.**:** :* *::*: *:* .**.* : **:* :*::**: **:***.***.****** **.**::** ...*:.: . * :.**: : ** ::*..:** *.::*:*::.: *:*** **:*** ***:*:** :*: :* * : .:.: : :*:::* * *********..*.****:*:*:**:*:** :*:*.*:* ***********::***:..:**:**: **: : : :..* ********:** **.**: *** ** .*:** **.***.* ****:.* : *: :* ** **::*.**** **:::********.* ** *******:*:*********:*** ******:****************:: ..**** :**:**:***** *:* ***.*****:****.***. *** .: :*:: ****:* : **.***. **.*.*:: **:* ***** **:.**** *.** ***************** ** ** ** ** .**::******** ***:**:******** * .*. *:*****.**..* .***: :*:*:***:****.*:.************ * * ::***:**:*. ** *: *::*** ** **.*:*:**.*:*. ** ****::** * **:*:*:** : * :**: * :* :***:** :.* :.*********:**.**. * :*. ** :**. * ***::** :*:*.**:::*.. ", "identical_positions": 470, "similar_positions": 237, "identity": "44.72%" }, { "cls_id": "homologset.agr.MGI:1932545", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD27-1", "uniprot_id": "D3ZD27_RAT", "id": "D3ZD27-1", "name": "[heparan sulfate]-glucosamine N-sulfotransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MNLIVK--FRRSFRTLIVLLATFCLVSIVISAYFLYSGYKQEMTLVETTAEAECADIKNLPYRSIELKTIKPIDTS------KTDPTVLLFVESQYSQLGQDIIAILESSRFQYQMVIAPGKGDIPPLTDSGKGKYTLIIYENILKYVSMDSWNRELLEKYCIEYSVSIIGFHKANENSLPTTQLKGFPLNLFNNVALKDCSVNPQSPLLHITKGPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQTEK--SLSFLSSQTLYATIIQDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDAGDDLLLRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINLGYAVAPHHSGVYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNNIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIKGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLANFVHSWTNLKLQTLPPVQLAHKYFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLVIGPQKTGTTALYLFLLMHPSIVSNLPSPKTFEEVQFFNGNNYHKGIEWYMDFFPTP--SNITS---------DFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVITTGHWAPPDLKTLQRRCLVPGWYAVHIERWLAYFSTSQVILLIIDGQQLRSDPATVMDEVQKFLGVTPHYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRRYPPMDPESRTFLSSYYRDHNVELSKLLHRLG-QPLPSWLRQELQKVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQW8-1", "uniprot_id": "NDST4_MOUSE", "id": "Q9EQW8-1", "name": "N-heparan sulfate sulfotransferase 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MNLILK--FRRSFRTLIVLLATFCLVSILISAYFLYSGYKQEMTLIETTAEAECADIKDLPYRSIELRTIKPIDTS------KTDPTVLLFVESQYSQLGQDIIAILESSRFQYQMVIAPGKGDIPPLTDSGKGKYTLIIYENILKYVSMDSWNRELLEKYCIEYSVSIIGFHKANENSLPTTQLKGFPLNLFNNVALKDCSVNPQSPLLHITKGPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQSEK--SLSFLSSQTLYATIIQDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDEGDDLLLRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINLGYAVAPHHSGVYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIKGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLANFVHSWTNLKLQTLPPVQLAHKYFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLVIGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIEWYMDFFPTP--SNITS---------DFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVITTGHWAPPDLKTLQRRCLVPGWYAVHIERWLAYFSTSQ--LLIIDGQQLRSDPATVMDEVQKFLGVTPHYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDSESRTFLSSYYRDHNVELSKLLHRLG-QPLPSWLRQELQKVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3R1-1", "uniprot_id": "NDST4_HUMAN", "id": "Q9H3R1-1", "name": "N-heparan sulfate sulfotransferase 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MNLIVK--LRRSFRTLIVLLATFCLVSIVISAYFLYSGYKQEMTLIETTAEAECTDIKILPYRSMELKTVKPIDTS------KTDPTVLLFVESQYSQLGQDIIAILESSRFQYHMVIAPGKGDIPPLTDNGKGKYTLVIYENILKYVSMDSWNRELLEKYCVEYSVSIIGFHKANENSLPSTQLKGFPLNLFNNLALKDCFVNPQSPLLHITKAPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQTEK--SLSSLSSKTLFATVIQDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDEGDDLLLRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINMGYAVAPHHSGVYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIRGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLVNFVQSWTNLKLQTLPPVQLAHQYFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLVIGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTP--SNTTS---------DFLFEKSANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVISTGHWAPSDLKTLQRRCLVPGWYAVHIERWLTYFATSQ--LLIIDGQQLRSDPATVMDEVQKFLGVTPRYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLSNYYRDHNVELSKLLHRLG-QPLPSWLRQELQKVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3L1-1", "uniprot_id": "NDST_DROME", "id": "Q9V3L1-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase", "aln": "MTISGGNQHNNNANRKYEKLIKQPQMQFGSSVTGTQTDVDSCRDADADANAVRQDFSNFNKHFGNGHAITDRTMLLRLEDDVTTAAGIVTYKGKSNGNGNGNGNGSIGSISLDFNGSPTSSTSIGIASGSSSNTHLASGGGVGGIGGSEPAGWMCHCCNLIARRCFGINVRRCVLALLAITMVSIFYYTHYVDTGVFNGLIQRDT-HPAPIINCRMINSGGKHIRNASPAPDHRSEARLRIDPKVLVFVETTYSGLGRDIAELLVYNRIKYKIEVAG--KSLPVLTNLDKGRYGVIVFENLDKYLNMDKWNRELLDKYCREYSVGIVGFVSPSEETLVGAQLRDFPLFVNTNLRLRDASLNPLSSVLRLTRAGETAWGALPGDDWAVFQHNHSTYEPVEWAQRNTQEYPADSVGQVQLPLTTVLQDRGQLDGIQRVLFGSSLRFWLHRLVFLDALSYLSHGQLSLNLERMILVDIDDIFVGEKGTRLRPDDVRALIATQKNIAAMVPGFRFNLGFSGKYYHHGTREENLGDDFLLQNVQEFNWFSHMWKHQQPHLYDNLTLLMAEMHLNYAFAVDHNIPTDSGYSISPHHSGVYPAHELLYMAWKKVWNVKVTSTEEYPHLRPARLRRGFIHRNIMVLPRQTCGLFTHTMYIDRYPGGRDKLDESIQGGELFQTIVYNPINIFMTHMSNYGSDRLALYTFQSVIKFLQCWTNLKLASAPPVQLAEMYFRLHPEEVDPVWGNPCDDVRHKKIWSKTKNCDSLPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGDVIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQ--LHIIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNKCLGKSKGRQYPAMDERSAKLLQRYYLNHNTALVKLLKKLGSRPIPQWLKDDLSTGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** : : ..* :: * :: :***. :::: :* : : :* * : : : . .::. .* : **.**:***: ** **:** :* .*::*:: :* .:* **: .**:* ::::**: **:.**.******:*** ****.*:** ...*::* :**:.*** : .*: *:*. :** *.:*::*:. :. *.***:**::**:*****:** :: :::: : * . : :*::** * *********..*.****:*:*:**:*:** :*:*.*:* ***********::***:. .**:**: **: : : *..* ********:** **.**: ***:**:.*:** **.***.* ****:.* : *: :* ** **::*.** : **:::********.* ** ******.::**********:*** *:****..***************:: ..**** ::**:**:***** **: ***.*****:****.***.**** .: :*::.****** : ******. **.*.**: **:* ***** ***.***: *.** ****************** ** ** ** **:.**:*************::*::*******: .* :* *:*****.**..* .*:*: :*:*:***:****.*:.************ * * .:.**:**::.. ** ** *:.*** ** ** *:*:**:*:.:.* * ****:*** :* **:*:*:** : * :**: * :* :***:** :. :.*********:**.** .* .:*. ** :**. * ***::** :*:*.**:::*.. ", "identical_positions": 465, "similar_positions": 250, "identity": "44.16%" }, { "cls_id": "homologset.agr.MGI:1932557", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIN6-1", "uniprot_id": "LETM1_RAT", "id": "Q5XIN6-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRGPARLASP-RAASPRGSLRDRACLSCTRTVGLTSHE------------SVLSRCCTP-ANPVYLYFKSEPLS---CWTQRPECQGTVAR---AAWTPASAR--------LVVTGPQYLPVRGWHSSSPLGEDSMIEKSLKSLKDKNKKLEEGGPVYSPPAQVV-VKKSLGQKILDELKHYYHGFRLLWIDTKIAARMLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTFETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGNATKD------FSAFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLYHEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQEEAAIQQEHLE-ELKRAA----------------ETAKDIQPEVAEATVPGRPGAELQPKMVDVIPPSEILKDTAPVLEGLKGEEITKEEIDILSDACSKLKEQKKS------LTKEKEELELLKEDVQDYSEDLQEIKKELSKTGDEKYIEESTASKRLS--------------------------------------------------KRVQQMIGQIDGLITQLETTQQ--NGKLDPAAASSPTGESVISVDELISAMKQIKHIPEHK----LISLTSALDENKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKVEEKEKAKEKAEKE-AAEVKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2I0-1", "uniprot_id": "LETM1_MOUSE", "id": "Q9Z2I0-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRGPARLAPP-RAASPRGSLRDRACLSCTRTLGLTSRE------------SVLSRCCTP-AHPVYLCFKGEPLS---CWTQRPECQGTAAR---TTWTPASAR--------LVVTGPQYLPVRGWHSSSPLGEDSVIEKSLKSLKDKNKKLEEGGPVYSPPAQVV-VRKSLGQKVLDELRHYYHGFRLLWIDTKIAARMLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTFETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGNATKD------FSAFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLHHEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEKVDNKAKLEATLQEEAAIQQEHLE-ELKRAS----------------EAVKDIQPEVAEATLPGRPGPEPQPPVDDVILPSEVLTDTAPVLEGLKGEEITKEEIDILSDACSKLQEQKKS------LTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYIEESAASKRLS--------------------------------------------------KRVQQMIGQIDGLITQLETTQQ--DGKLGPSQS-TPTGESVISITELISAMKQIKHIPEHK----LISLTSALDDNKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKIEEKEKAKEKAEKE-AAEVKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95202-1", "uniprot_id": "LETM1_HUMAN", "id": "O95202-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRAPARLPPPPRYTVPRGSPGDPAHLSCASTLGLRNCL------------NVPFGCCTP-IHPVYTSSRGDHLG---CWALRPECLRIVSR---APWTSTSVG--------FVAVGPQCLPVRGWHSSRPVRDDSVVEKSLKSLKDKNKKLEEGGPVYSPPAEVV-VKKSLGQRVLDELKHYYHGFRLLWIDTKIAARMLWRILNGHSLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTFETQSLKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGSATKD------FSVFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRS----------------EVAKDFEPERVVA-APQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKS------LTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLT--------------------------------------------------KRVQQMIGQIDGLISQLEMDQQ--AGKLAPANG-MPTGENVISVAELINAMKQVKHIPESK----LTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEEKVEEKEKAKEKAEKE-VAEVKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY46-1", "uniprot_id": "LETM1_DANRE", "id": "Q1LY46-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLTRSR-TPLLKTSRSLKNEFRKGKLSEGACFNCTALRLATNSP------------GVLGGIVWPHASSVQYLDNSSVLQRRLSRSPRLYCAILVPDPALPVHSRSTYH--------RTLAWPQNAPVRWVHTTGRLLDDSKVERSLRTLKDRNKKLEEGGPVYSPTVDAEPVRRTIRQRVIDEVKHYYHGFRLLWIDTTIAVRMLWRVLNGHILSRRERRQFLRTCADVFRLLPFLVFIIVPFMEFLLPVALKLFPNMLPSTFETQSKKEERLKKELRVKLEMAKFLQDTIEEIALRNKASKGNVTEE------FSTFFQKIRDSGEIPSNEQIIRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLIMKLRAIRADDKLIAEEGVDSLTANELQAACRVRGMRALGVTEERLREQLKQWLELHLNQHIPTSLLLLSRAMFLPDTLSPADQLKTTLQNLPEIMAKEAQVKVAELDFSKVDNKTKLETTLQEEAAIRQENRERELERLAD---------AAEKAKEQTQSQEAEVLEVEGERRVDAEHALSSVDVAIHSETLRDTAPVLEGIKGEEITKEEIDMLSDACTKLKEQKNL------LTKEKEELEDLKDDVQEYSEDLEEIKRELSKTGQEKAVEESKASQRLS--------------------------------------------------KRVNRMIGRMDKIITELEKDKMVLDGQMDSETT-PPIGENLISINELITVMKQIQNIPEHK----LLSIADALDENKDGKIDIDDVIKVVELIDKEDIDISTNQVAEIMVMLQKEEKLMEKEKAKEKVEKEQAAKIQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91927-1", "uniprot_id": "LETM1_DROME", "id": "P91927-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MNALLRHKGRNLRTSHLAQNVYKRFLKSNCCACSSVNVTDEPAKEDELPRRSASTSVLELSRSLGTYRRFQPHANYGYDYSGYGFRHLHTSRTLLETSSSKIDATVKKLKNQQKEKVEEIMKEVANGQAAAVRASSAATATASSEKGQNASATAGSTSATASTTSLAKTADKSVAKPKKPLRTRIWDELVHYYHGFRLLFIDVAICSKLLWRVLNGKTLTRRENKQLQRTTSDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSLSVRLEVAKFLQQTLDQMPVQHKEHSSEEAKQ------FEAFFTKIRNPTEPVSNDEIIKFAKRFDDEITLDSLSREQLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARGMRAYGLTEERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISDDSITTDKLKETIRVLPDAVGAHTRHAIGESEG-KVDNKTKIEIIKEEERKIREEREEEREETIAKRSAIKEEIPAPYVFAEKLSGSQDLLDHKEQSSVSETDKGISSTDVQLLSEALKTLSSDKQLVVEKETIKELKEELADYKEDVEELREVRQVVKEPVRESRAAKLLYNRVNKMISQLDNVLNDLEARQHQIKQAESSDYAASSPTVEPQQMVHIDELVATIRRMKEASDEERFKVVGDLLVKLDADKDGVISVNEITKAVQSIDREATNIDKKQLEEFTELLSKLASRRRHEEIVHIDDLMNNIKVLKETSDEARLKHIEAVLEKFDADKDGVVTVNDIRKVLESIGRDNIKLSDKAIEELISLLDKEQVLQAEQKIEKAIAKSMKEAEKLKSEVDKADKDLSKLVNDIHDSAKEIQDIANEMRDKEETVPDKAKELKAEPAFKDTAKTLKDNAKDLDDLAKDPKSDPKSPTKASTGSGPAGLSGGGPSSGSSGIATGSTTESALREAAERQMEKILPSTDIGLPPTIQTPSQPPTSKKATATASTLSTTITAKKLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08179-1", "uniprot_id": "MDM38_YEAST", "id": "Q08179-1", "name": "Mitochondrial distribution and morphology protein 38", "aln": "---MLNFASRASCVTRRQASLYFVKNQGPRLIASTIPSCHWPLRAQGVQ-----------------------------------------------------------------------------------------------PNYPLSLRFYSTDKSKSVTKPVAPTSTDAPAKPKETLMVKVKHALKHYANGTKLLGYEIKVSTKLLIKFAQGYELSRRERNQLRRTMGDVFRLIPFSAFLIIPFAELFLPFALKLFPNLLPSTYESGKDKQAKRNKLIEIRKKTSEFLHETLEESNLITYNTIENAEKKQKFLNFFRKLYSAKEGKIMTFQHDEISAIAQMFKNDSVLDNLSRPQLAAMSKFMSLRPFGNDNMLRYQIRSKLKDIMNDDKTIDYEGVESLSQEELYQACVSRGMKAYGVSKEDLVDNLKVWLELRLRQKIPSVLMVLSSTFTFGG--------------LPKENYSKAFSPLAEKKETKSKYDDLLDLYYDGILQVLS-------------------------------------------SIPDPVYNVAKLDVS-ESKSSAAETEAEKQVAEKKIKTEEKPEETAIPKEEATAKES----------------VIATTASAVTPKLVVVNEKAETAKTEEISQEKENAEPT---------------------------------------------------------------------------------------------------DSAEATEAEEKK-------------TSDDNEFKLNVLKEQEELIKKEEEEAKQRASREHVPDDINLDEEEEAKSVPPIPADQAAKTFVIKKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06493-1", "uniprot_id": "YLH47_YEAST", "id": "Q06493-1", "name": "LETM1 domain-containing protein YLH47, mitochondrial", "aln": "---MLKYRSLPIKRAIHHPAPGITPISPRIMVSRLRVIPSFNLKFNRWN-----------------------------------------------------------------------------------------------SSVPESS--KKELKTTDGNQESASKVSPVKEKEKVPFKVKMQKALRHYWDGSKLLGLEIKISSKLLMKSAAGYPLTRRENLQLKRTTQDIVRLVPFAAFLIIPFAELLLPFALKLFPNLLPSTYESSKKRENKLENLRNTRKLMSEIIKNNK---SHFKPNNISEEQK-----ALFNRFYTHVRATGVPESRQQLIEVARLFTDDTVLDNVTRPYLIALAKYMNLQPFGTDVMLRYRIRYKMLELKKDDLSIYYEDAEQLSLSELKTACASRGIRSVDVEPSVLYSNLRLWLNMRLKDKIPSTLLIMATAYNYGN--------------VQSK-----------------------ESLYDALCDVLI-------------------------------------------GIPDELYHEVKVNVVKEDEASAKQKLKQLREQEEIMKEEEQQEENAIVS--------------------------------------VKDELSLDDQDKNIDAAAPDVKPH---------------------------------------------------------------------------------------------------DTKPIGEAAAIK-------------EK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . : . . . . : .: :: . : ** .* :** : :. ::* : * *:***. *: * *:.**:** .*:::** *::**. :*:**.:****::: . :: : .: : ::::::. . : * :: . ..::: .:: * :: .**.::* * *:.: :.*..:*. :**::: :: : ** * *..:.* ** ** **::: .: . * :*: *::: * ..:*. *:::: : . : . : : : :. .: : * : : . . . ", "identical_positions": 61, "similar_positions": 131, "identity": "5.98%" }, { "cls_id": "homologset.agr.MGI:1932575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT88-1", "uniprot_id": "D3ZT88_RAT", "id": "D3ZT88-1", "name": "Transcription factor Sp6", "aln": "MLTAVCGSLGSQHTDAPHSSPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGTED--GSWWDLHPGT--SWMDLPHTQGALTSPGHPGALQPALGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKVLEAAAPESQGLDSSLDAAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEG---AKEEAAAAAQGE--GKAGGVVESPGGKGKREAEGSSASSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESX2-1", "uniprot_id": "SP6_MOUSE", "id": "Q9ESX2-1", "name": "Transcription factor Sp6", "aln": "MLTAVCGSLGSQHTDAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGTED--GSWWDLHPGT--SWMDLPHTQGALTSPGHPGALQPALGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKALEAAAQESQGLDSSLDAASRPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEG---AKEEAAAAAQGE--GKAGGVVEPPGGKGKREAEGSSASSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SY56-1", "uniprot_id": "SP6_HUMAN", "id": "Q3SY56-1", "name": "Transcription factor Sp6", "aln": "MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAED--GSWWDLHPGT--SWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEG---AKEEAAGAASGE--GKAGGAVEPPGGKGKREAEGSVAPSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IPM5-1", "uniprot_id": "A0A0R4IPM5_DANRE", "id": "A0A0R4IPM5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MAHPYDPWLRAGPPQDEVSVSGWWDVHTGAPAGWMDLQG-AGLGAGPGQSGSMS----SYTAEPQMCCLSPPGSGMHFPPEGFKMEPLPQDLLPLPQASASFSSEEQQDAVAAAGRPKPQRRASSRAPGQASCRCPNCLSAESLGNSG--DASKRKHLHNCHIPGCGKAYVKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGAKRFGCSSCPRVFLRADHLAKHMRVHESPSQSTEETHAAAAGTSTGTSSALLRVKTETDNGDDDATLANS-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* *:.*:*. * * ..***:*.*: .**** * :.**:.*::. .*..: *:*. .* *: * . . * . *: .*: :.:: .*.*** .**: .*:.**: *******.** ** . *..*:***************.********************************************:*:* *: *.***:*:*******:.**. :.**: .** * *.:.. :. ..: : :.: * * ", "identical_positions": 135, "similar_positions": 76, "identity": "35.06%" }, { "cls_id": "homologset.agr.MGI:1932576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5QD51-1", "uniprot_id": "AKA12_RAT", "id": "Q5QD51-1", "name": "A-kinase anchor protein 12", "aln": "MGAGSSTEQRSPEQP-AGSDTPSELVLSGHGPAAEAS-GAAGDP--ADADPATKLPQKNGQLSTVNGVAEQGDVHVQEENQEGQ--------------EEEVVDEDVGQRESEDVREKDRVEEMAANSTAVEDITKDGQEETSEIIEQIPASESNVEEMVQPAESQANDVGFKKVFKFVGFKFTVKKDKNEKSDTVQLLTVKKDEGEGAEASVGAGDHQE-------PSVETAVGESASKESELKQSTEKQEGTLKQEQSSTEIPLQAESDQAAEEEAKDEGEEK--------------------------QEKEPTKSPESPSSPVSSETTSSFKKFFTHGWAG-WRKKTSFKKSKEDDLETAEKRKEQEAEKVDEEEKEKTEPA---------------SEEQEPAEDTDQARLSADYEKVELPLEDQVGDLEASSEEKCAPLATEVFDEKMEAHQ-EVVAEVHVSTVEKTEEEQGGGGEAEGGVVVEGTGESLPPEKLAEPQEVPQEAEPAEELMKSREMCVSGGDHTQLTDLSPEEKTLPKHPEGIVSEVEMLSSQ-ERIKVQGSPLKKLFSSSGLKKLSGKKQKGKRGGGG-DEEPGE------------------------------------------------------------------------------YQHIHTESPESADEQKGESSASSPEEPEETTCLEKGPLEAPQDGE-AEEGTTSDGEKKREGITPWASFKKMVTPKKRVRRPSESDKEEELEKVKSATLSSTDSTVS-----------------------------------------------------------------------------------------------------------EMQDEVKTVGEEQKPEEPKRRVDTSVSWEALICVGSSKKRARKA--------------------------------------------------------------SSSDDEGGPRTLGGDSHRAEEASKDKEAGTDAVPAST------------------------------QEQDQAQGSSSPEPAGSPSEGEGVSTWESFKRLVTPRKKSKSKLEEKAED----SSVEQLSTEIEPSREESWVSIKKFIPGRRKKRADGKQEQATVEDSGPVEINEDDPDVP------------------AVVPLSEYDAVEREKMEAQG---NAELPQLLGAVYVSEELSKTLVHTVSVAVIDGTRAVTSVEERSPSWISASVTEPLEHTAGEAMPPVEEVTEKDIIAEETP-VLTQTLPEGKDAHDDMVTSEVDFTS---------EAVTATETSEALRTEEVTEASGAEETTDMVSAVSQLTDSPDTTEEATPVQEVEGG---VLDTEEEE---------------------------------------------------------------RQTQAILQAVADKVKEESQVPAT-QTVQRTGSKALEKVEEVEEDSEVLASEKEKDVMPKGPVQEAGAEHLAQGSETGQATPESLE-VPEVTADVDH---VATCQ------VIKLQQLMEQAVAPES--SETLTDSETNGSTPLADSDTADGTQQDETIDSQDSKATAAVRQSQVTEEEAATAQKEEPSTLPNNVPAQEEHGEEP-GRDVLEPTQQELAAAAVPVLAKTEVGQEGEVDWLDGEKVKE-----EQEVFVHSG-------------------------------------------------------------PNS--QKAADVTYDSEVMGVAGCQEKESTEVQSLS-----LEEGEMETDVEK--------------------------------------EKRETKPEQVSEE-GEQETAAPEHEGTYGKPVLTLDMPSSERGKALGSLGGSPS-LPDQDKAGCIEVQVQSLDTTVTQTAEAVEK--VIETVVI-----------------------SETGESPECVGAHLLPAEKSSATGGHWTLQHAEDTVPLGPES-------------QAESIPIIVTPAPESTLHPDLQGEISASQRERSEEEDKPDAGPDADGKESTAIEKVLKAEPEILELESKSNKIVLNVIQTAVDQFAR-TETAPETHAYDSQTQVPAMQAD----------------------------------------------SQGAQQMLDKNES-----CQDETPSAAAQR---------------------------GLASPDRSGGMGSASEMLAALAVESAGVKVS-------------------------------------IEKLPPQPK-DQKEHAADGPQLQSLAQAEASASGNLTKESPDTNGPKLTEEGDAPKVEVQEEEMSTKSVKENKAQAEED-----LQEPKGDLAES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTQ5-1", "uniprot_id": "AKA12_MOUSE", "id": "Q9WTQ5-1", "name": "A-kinase anchor protein 12", "aln": "MGAGSSTEQRSPEQP-AESDTPSELELSGHGPAAEAS-GAAGDP--ADADPATKLPQKNGQLSAVNGVAEQEDVHVQEESQDGQ--------------EEEVTVEDVGQRESEDVKEKDRAKEMAASSTVVEDITKDEQEETPEIIEQIPASESNVEEMAQAAESQANDVGFKKVFKFVGFKFTVKKDKNEKSDTVQLLTVKKDEGEGAEASVGAGDHQE-------PGVET-VGESASKESELKQSTEKQEGTLKQAQSSTEIPLQAESGQGTEEEAAKDGEEN--------------------------REKEPTKPLESPTSPVSNETTSSFKKFFTHGWAG-WRKKTSFKKPKEDDLETSEKRKEQEAEKVDEEEGEKTEPAP--------------AEEQEPAEGTDQARLSADYEKVELPLEDQVGDLEALS-EKCAPLATEVFDEKTEAHQ-EVVAEVHVSTVEKMTKGQGG-AEVEGDVVVEGSGESLPPEKLAETQEVPQEAEPVEELMKTKEVCVSGGDHTQLTDLSPEEKMLPKHPEGIVSEVEMLSSQ-ERIKVQGSPLKKLFSSSGLKKLSGKKQKGKRGGGGGDEEPGE------------------------------------------------------------------------------YQHIQTESPESADEQKGESSASSPEEPEEIACLEKGPSEAPQEAE-AEEGATSDGEKKREGITPWASFKKMVTPKKRVRRPSESDKEEELDKVKSATLSSTESTAS-----------------------------------------------------------------------------------------------------------GMQDEVRAVGEEQRSEEPKRRVDTSVSWEALICVGSSKKRARKA--------------------------------------------------------------SSSDDEGGPRTLGGDGHRAEEASKDKEA--DALPAST------------------------------QEQDQAHGSSSPEPAGSPSEGEGVSTWESFKRLVTPRKKSKSKLEERAED----SGAEQLASEIEPSREESWVSIKKFIPGRRKKRADGKQEQAAVEDSGPGEINEDDPDVP------------------AVVPLSEYDAVEREKLEAQRAQENVELPQLKGAVYVSEELSKTLVHTVSVAVIDGTRAVTSAEERSPSWISASMTEPLEHAEGVATPPVGEVTEKDITAEATP-ALAQTLPGGKDAHDDIVTSEVDFTS---------EAVTAAETTEALRAEELTEASGAEETTDMVSAVSQLSDSPDTTEEATPVQEVEGG---MLDTEEQE---------------------------------------------------------------RQTQAVLQAVADKVKEDSQVPAT-QTLQRAGPKALEKVEEVEEDSEVLATEKEKDVVPEGPVQEAETEHLAQGSETVQATPESLE-VPEVTEDVDR---ATTCQ------VIKHQQLMEQAVAPES--SETLTDSETNGSTPLADSDTPNGTQQDETVDSQDSNAIAAVKQSQVTEEEAAAAQTEGPST-PSSFPAQEEHREKP-GRDVLEPT-QALAAGAVPILAKAEVGQEGEAGQFDGEKVKDGQCVKELEVPVHTG-------------------------------------------------------------PNS--QKTADLTRDSEVMEVARCQETESNEEQSIS-----PEKREMGTDVEK--------------------------------------EETETKTEQASEE-HEQETAAPEHEGTHPKPVLTADMPHSERGKALGSLEGSPS-LPDQDKADCIEVQVQSSDTPVTQTTEAVKK--VEETVAT-----------------------SEMDESLECAGAQSLPAEKLSETGGYGTLQHGEDTVPQGPES-------------QAESIPIIVTPAPESILHSDLQREVSASQKQRSDEDNKPDAGPDAAGKESAAREKILRAEPEILELESKSNKIVQSVIQTAVDQFAR-TETAPETHASDLQNQVPVMQAD----------------------------------------------SQGAQQMLDKDESDLQVSPQDGTLSAVAQE---------------------------GLAVSDSSEGMSKASEMITTLAVESASVKES-------------------------------------VEKLPLQCK-DEKEHAADGPQHQSLAKAEADASGNLTKESPDTNGPKLTEEGDALKEEMN------------KAQTEEDD----LQEPKGDLTES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02952-1", "uniprot_id": "AKA12_HUMAN", "id": "Q02952-1", "name": "A-kinase anchor protein 12", "aln": "MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNGQLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAG---AGDHKD-------PSLGA--GEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQ-AVEECKEEGEEK--------------------------QEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAG-WRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLT------ASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTE--------EQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQ-ERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGD--EESGE------------------------------------------------------------------------------HTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGE-AEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTAS-----------------------------------------------------------------------------------------------------------EMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRG--------------------------------------------------------------SSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGS------------------------------QEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVP------------------AVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTP---------EAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGG---VPDIEEQE---------------------------------------------------------------RRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDS--VETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPA-PSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQ--EADQYADEKTKDVPFFEGLEGSIDTG-------------------------------------------------------------ITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREMVVQVER--------------------------------------EKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANI-----------------------LETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDC-------------QAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEV--KVSVAIEDLE-PENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKAD----------------------------------------------SQDAGQETEKEGEEPQASAQDETPITSAKEESESTAV--------------------GQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDG----HALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IC31-1", "uniprot_id": "A0A0R4IC31_DANRE", "id": "A0A0R4IC31-1", "name": "", "aln": "MGATPSVQR--------DAKSPEDAPEDVSAPLSDAHDGETADG---------KPLQKNGQISISSLNGKTDDQTEYNGHTEEN------------------PPAEVGQTDTISPKEDSPETIEVHQEEVAPQMNGEKGDDSANADEITTAEEKVVEEKQE----EANEVGFKKIFRFVGFKFTLKKDKNEKTEPVQLLTVKEAESGADAATEEKKEEPA-------AEEDRSVEEKSPETTENEAKAEEVTEKAEEPAEQTVVDAPSETEKVSDIETEKPAEETGT---------------------ISEKEPEPEVPAESPTSPPSQETQSPFKRFFTQGIFSNLRKKASFKKPKDEEHVKEKPVEEDIKETEETAEG--------------------------VPEATEEAKVDAENEPAEGEQIEKPSETVETKAETTTETTAETTNEVTPTEK-------------------------------------EEQQDLKVEAEATSEVETVTHTEPAQAPAVETTQPTDDAKTSDKPDISEEAP----TEPEILSSQ-EKSKAHGSPLKKLFTGAGLKKLSSKKHKNKKDAESKQTESSE------------------------------------------------------------------------------QTAETVQSTESTEPQKPDSGASSPEESGEHVVGEVAQAEVAQAVEPDGDAVTSDGEKKKEGILPWSSFKKLVTPKKRVKRPSESEDEAPGDKPKSSTLSSTESAISDEKADEPKPSE------------------------------------------------------------------------------EVPSKEELKEEAKEESQAESKTEPKAEKSESVAEEPKRKMDTSVSWEALICVGSSKKRARKT--------------------------------------------------------------SDSDDEE-----AKIEEEVQPSEEEPIKTAESPLVSS------------------------------GEADHENLASSPE-----PEGELVSTWESFKRLVTHRKKAKAEDKSDEAS-----GPEQTTSDSETPKEESSFSLRKLIP-RRKKKSDGKQEQVSSDVG----SAEDDSDTP------------------AVVPLSEYDSE----------------PSAEAAVKAEEVKQES---------ATVTQAKASAEDRSPSWISTTVENVEDETEGNQLSDIPEEGDTAATP--------------KSTDNTIAEDIVELTS---------EAVTALEQVEET---------------EMVSAVSRVTASPDTSGETTPVPGDGVERKTDVVIQEAV---------------------------------------------------------------ETISVTTNAMAVTMTEEQETVVAITTDALLVESATKEQKTVLVAHEKNEAVAVCTGLDTSEIRAVEEESLNQKPSVESATVVSQPLVTEVAVEEKT----------------QEPERVTVTEDEVH--EAQTSGVQAELKDQPIENAIEEKAQFEEIKDTPIAETVADIHEVAAVKVAVISAVQQEPEILEEPVMAEKSPEIES--AGPVEATVEEAICAQTAEVTEVAVAEGEKVQELDDVKETVATVEVASVENVSTA-------------------------------------------------------------VTEEVMATLPEVPASQIAGSTEDPIPVVAATEEFA-----VIKETICVSSIS--------------------------------------ETTESHSADIAKETLMENVPVVLSTGDHKMQVAVNEVEVVS---AQGVVEGNIEAASTKLSVALEEVTENVKEETEIIQATQVTEAEIIEKQSS-----------------------VIVQEIIQNVVENFAEAHGEQNVSEKTTEESCITSAEVKVNE-------------ISVETTEEGSSTDKLAASDNVCKDVEETRIVTEKPPKIVNEAIQIAETVPVSITDEIQAQNEEVASVSVADVHQETEVTKSEVELKQAEEKS---QSTKNEEGISEVESD----------------------------------------------LKEVQAEIQQEIKAVPEEKTAETSVTVASQ---------------------------DQVVAEQCQVTLTAVQIETAQEFNVGVVNVIN---------------------------------ADDVPETNMKEDCSEGQESTEDRPQNDLEEPQTKVSTNQE-ESRGPDCQKTDAKNVPAKLEAASEMTS-------NATAAEEVGNEIEPVSTEVVTVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F983-1", "uniprot_id": "E7F983_DANRE", "id": "E7F983-1", "name": "", "aln": "MGAATSSARRD-----SRGEEDAAAEELTAAGSDAPEDGSAADD---------KLLQTNGLISNLNVKTKEPADELNCQFEER-------------------VLADVG-SGFVTLKEDGTETLEDLQNLDPLQPNAKNESGEMVNAGVTLKEETEVDSQVN----DINEVGFKRIFRFVGFKLTLKKDACEKTQANEQKETEENEQKEDNASEEAKDEDSDVAAIEITPDETHKSEESSDAAEPPSQQTDNETELDQDIKIVEFHVVDTPGKEMEKESSIEPEEPMSPIKQFFTQGIFASLRKKKKEEEIQKESKEEELKENEKTIAEEEAEKQDSKCMCLDIPYIISEDGKDSQEKGDDSLLPEGELQNSLEKDKVQGSPLKRLFRKFSSRRQREGKAAEKVAEVEEQVSEQPKPSSELGKAEEPLIGETVIEEPTVGEPKPADEQPVGDVGPQESKKKSDTTVSWEALICGGSAKKRARKTNEDEMSDKGQEHDKVTDSPLGSSIEGDYDHLTSSNEQTGSPAEGEVGSTWKTFKKMVTPKRKVRPGESSTPEQIPSDGEMSKDESFSKKKLIPGHKKRKSEAKQDQTSSDEVAKDHESDDETPAIIPLSEYEVIEPETLKEMNEQRVEITIEHEMPEIPSQALEKDTFKTVTKVSSNTAPAIIQSLSEDFEELTDFLSKHQQLSDIPEEGIEESIETPVSSAEWTTQDDTLAEDIVELTADAVTAPEPESILGDDTTEMVSALSQLTESPRSSGHVTPVSAEYDVQTSDAILHEAIQSICMTPSVQSITTKDESQKSLAVSFSPYIVQSSTPEETKVLVAHKKTEATAICIGLVSQEIESVEKHLPAPLVEAILEICDTVPTEVASDNFTDEHEVAGIGTDEVYEAEIKDVKTEFQERIVNEEESTSESERDIEQVIQLVTEPLVDESEETHIKDKKEESTTGIELRQDIDTMQSESGLDQVMLDITHGPELECPSYSTDEIAYNQLAAGEPTLDTISQVDEQETVDKILDITKAIDAPVEDTASAVECLEIKENVNIISPITDQIQVETIVLEDSLQIKDVPSIQADVKDADLSVDDSGDMSIKDIGEKMEASGDEKIAQQEIKEDHLEEETGDVVSSELVQNVKAENIAESIDDLLVKEQLPAEKASLTEPVLEKAKEAHKDVTDTDVDDKVVDNAHDRADRIFVKDELAPKNEQPLTDTDSNETENQDLSTHLNSMSESPGIVVGETEKGQTEDIIPVVSEFSKDVLEPTKTPTEPEVSCEAIPTSLGIPSAEVEVKSIPEEIVTFKTEECSQDIQQNEQLQTSENNKTSKVLEMVAITENTTKQLEQEKAIVAEPEAQVLTMSELPKATEQEGDSSEVTVVHGEANDSDQAQAVTLTDTIRTAVQDEIYKEAVASILKPERVDSRMTVTEENEAYADSMQKCEPLRQKTEMTLSKELQVDKTNNKDEILAVTEVIPKEQVPPLRSEVTAEMPDVTVSEVQTKVESELRAATLEVTEPKVEMPVITEVTVESAVVTEPEVERPIVTSVVAELEVETPVVTSTTKATDTHTSQIIDADTTELTTVIKEDVEEKPTVISVVVTPATPLDEATPVLTQSHESRVVDEVKDESVEPRAIETPKVEAVIVRSVLAPAVEIQNVIPVVKAPNLGSVTMTEGSSPVVEATVLETTAATAIKPDVVEIPVVQTPNIDSVIMLPAITSVPSKEVTLDLTSFAETPLDNVTEIPVVSLTSVKPTVAALMQTPDAEIQARIPMTVTEVACPVVVTTDVTPVAPGGIVIPAVETPHATSSTVVLKTPTQISVTVTEAEAPVTTSVAASAVIPVEETVRVKETSPPGVVSVTAAVETPATIPVVQTPAVKLSSLAMVETPVVTPVVLMPNQVSEKAKETALSAVISAVETAPVIPAEEYPVVKLTQVAVVEAQVVHPMAETPGQGLVRLTETSLPAIVSDVTAAVETPAIISVVETPVVMTTPVTNFELPVVSTAVEIPGLVSEIVKETASPTVVSAEETLPVIPVVQTPTVKSTEVAVVEPPVVTLDQVSSLVSETSPPVDVSTVEAPAVIPVVETQVVKSTPVAVIEIPVVTPMVQTPGEVSVIVKETAPPADDLSVETSPVMPIIENLVVKSTPVSVLDAPAVTPVVQTPGQGSASVIETSPLPIVSGATALVEAPIMIPVVETPVVMDEMPIMTKVIQTPGQDLMMVKETTPQVVSAVETPLVIPVVETPVVTSTQLKAVEATGVLPAVQALAQDSVRETETLPQAIVSGVTAAVEAPTMIPVVEIPVAMVEIPVVPPVVQGPDQGSVRVSETSPPSVVSGVTAPVETPAMIPAVETLVVMSTPVAAVETPVVTSVVQTASQVSGIVKEIVPPADASAVTSRDETPAVNSTPVAVVDPLVLTPVVQISEQVSMKVTEALPPAEVETVVLTAVVETAVVNPPPTAVTETPVLTPVVQISEQVSLTVKETSPPAVPETSVLTLIVETPVVIPAPAAVTETPVLTPVVQISEQVLLRAEETSLPAVAETSVSTPLVETSVAKSAPSAVTEIPVLTPVVQISEQVSLTVKETSPPAVPETSVLTQVVETPVVIPAPAAVTETPVLTPVVQISEQVSLRAEETSLPAVAETSVSTPLVETSVAKSAPSAVTETPVLTPVVQISEQVSLRAEETSLPAVAETSVSTPLVETLVAKPAPSSVTVTPVLTPVVQISEQTSVRVTETLPPAVAETAVLTPVVETPVAKPAAVTETPVLTPMVQTPRQVIVTVTETALPVVASAVNAAAEKPFVVPVESSVLKPTLMTTPIMTSVVERSVLSLVLETTAPTTIALTERPVMIPMVQTPALVSVIVKETAPPVVLPPVTTTAKIPVKSPAVETQAVKPTSAATETPIPVVPISESPVVTPVGEQVAETLTTPATPSVITPTIETVMESPAEVSEEKAKQQTEVAEALTLAPVVEAPATPQPVVTPDVKEAIVQVVAEDKKEANTEPYVVFEDAVQQQEVNTSIQENPKGPMPHKAVVPSTEPQPEMEEDVWEDAVDNIGDSHCQLTHTEGESQDTAAKEASEAVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .* : .. . . . :.* * *.** :* . : : :** : . .. : . . . .*. ::. : : *::***::*:*****:*:*** **.:. : .:: * . :. . * :.. :* . . .. . . . . : * ** :* : *. .: .*: . .: : . :. . : * :: : :: *. . : :.:.: .:: .* : * . . : : . : : .. : . : : * :.*: * * .. . ***:.. :* ..*:.: . . *..: : .:. :. :: .**.* . : * : : *:.. * : . :.:.: .. :* * . . : ::.* : * : : : .* ..*.:* :: :. : *..*:: : *. *:: . : . :: : : * . * : . : .. *: ::: * . . . : : .. . . ::: :* .: . .: *:. ** . **:: *: . . ..: : .. : . * : . . * .. . . . :* :*:.* . *:.* : ..* : .* . : . . :: : : : : . . . .. * ..:. . . : . . . . : .: . .: . : * . .. :. * . : . . . . . . : : : .. . . :: .. : . : . .: : : . * : . . :. . . :.. : : : : .. . . : . : .: : :::. : . . . * . : . . . * . . . *: : . .: . . :..* .: . . : *: . : ", "identical_positions": 98, "similar_positions": 379, "identity": "3.2%" }, { "cls_id": "homologset.agr.MGI:1932610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AC09-1", "uniprot_id": "A0A8I6AC09_RAT", "id": "A0A8I6AC09-1", "name": "Nucleolar complex protein 3 homolog", "aln": "--FFQRRNKKQVPSFRKLIKTSKVKLENKLKNKQFKQQSTIKKYRKEQR----KLRQAVKDAVSKKPFPLEDPKSKRPVKRIEREEEDEEEALPLDMLDEDDLQLIKDLGQKASFLTRDLSSSEPVHIKKRKHESVIEKYEKVPRTLQTAPEKELIHLLPIKDKSG-IIPQTREKPVTAIQQEEE-EEEEPEVEEEVIEEPRQE---------------------LTIEEHVIERKKKLQDKKIQIATLASAILSDPESHIKKLKELRAMLMEQDPD----VAVTVRKLAIISLMELFKDITPSYKIRPLTEAEKSAKIRKETQKLREFEEGLVSQYKFYLENLEQIVKDWKQRKLKKSNVVSLKAYKGLAEVAVKSLCELLVALPHFNFHNNIIVLIVPLMND---GSKSVSEMCCEAVKKLFKQDKLGQASLGVIKVISGFVKGRNYEVRPEMLKTFLCLRIKEVEVKKDTEDINKPKRFMTFKEKRKTLSRMQRKWKKAEEKLERELREAEASESTEKKLKLHTETLNIVFVTYFRILKKAQKSPLLPAVLEGLAKFAHLINVEFFDDLLVVLHTLIESGD------LSYQESLHCVQTAFHILS-GQGDVLNIDPMKFYTHLYKTLFTLHAGATNDG-------------------------IEIVLHCLDVMLTKRRKQVSHQRALAFIKRLCTLALQVLPNSSIGLLAMTRILMHTFPRTDLLLDNES-QGSGVFLPELEEPEYCNAQNTALWELHALRRHYHPIVRRFAAHLLAGAPSEGSEALKPELSRRSALELFEAYSMAEMTFNPPVESFNSKKKDKFLQGDAFLNEDLNQLIKRYCDEAAPERPLDFTKCLKTSSR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI84-1", "uniprot_id": "NOC3L_MOUSE", "id": "Q8VI84-1", "name": "Nucleolar complex protein 3 homolog", "aln": "--MKARRNKKQVPSFRKLIKTSKVKLENKLKNKQFKQQSTIKKYRKEQR----KLRQAVKDAVSKKPIPLEDPKSKRPVKRMEREEDEEEEALPLDMMDEDDLQLMKDLGQKASFLTRDLSSSEPVHIKKRKHESVIEKYEKVPRTLQTAPEKELIHLLPIKDKSG-IIPQAREKPVTDVQQEEE-AEEELEDEEEVIEDPRKE---------------------LTIEEHVIERKKKLQDKKIQIAALASAILSDPESHIKKLKELRSMLMEQDPD----VAVTVRKLVIISLMELFKDITPSYKIRPLTEAEKSTKIRKETQKLREFEEGLVSQYKFYLENLEQIVKDWKQRKLKKSNVVSLKAYKGLAEVAVKSLCELLVALPHFNFHNNIIVLIVPLMND---GSKPVSEMCCEAVKKLFKQDKLGQASLGVIKVISGFVKGRNYEVRPEMLKTFLCLRIKEVEVKKDTEDINKPKRFMTFKEKRKTLSRMQRKWKKAEEKLERELREAEASESTEKKLKLHTETLNIVFVTYFRILKKAQKSPLLPAVLEGLAKFAHLINVEFFDDLLVVLHTLIESGE------LSYQESLHCVQTAFHILS-GQGDVLNIDPMKFYTHLYKTLFTLHAGATNDG-------------------------IEIVLHCLDVMLSKRRKQVSHQRALAFIKRLCTLALQVLPNSSIGLLATTRILMHTFPRTDLLLDNES-QGSGVFLPELEEPEYCNAQNTALWELHTLRRHYHPIVRRFAAHLLAGAPSEGSEALKPELSRRSAVELFETYSMAAMTFNPPVESSHSKRKDKFLPGDSFLNEDLNQLIKRYCNEAAPETPLDFAKCLESSSRQYRVNGLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WTT2-1", "uniprot_id": "NOC3L_HUMAN", "id": "Q8WTT2-1", "name": "Nucleolar complex protein 3 homolog", "aln": "--MKARRNKKQIPSFRKLIKTSKVKLENKLKNKQFKQQSTLKKYRKEQR----KLRQAVKDAVSKKPIPLENPKEKRPGKRIEREEEEEEEALPLDMMDEDDLQLMKDLGQRVSFLTRDLSSSEPVHAKKRKHERIIDKYEKIPRTLQTAPEKELIHLLPIKDKSG-IIPQTREKPVTDSNKDEEDQEEERELEEEIIEDPIQE---------------------LTIEEHLIERKKKLQEKKMHIAALASAILSDPENNIKKLKELRSMLMEQDPD----VAVTVRKLVIVSLMELFKDITPSYKIRPLTEAEKSTKTRKETQKLREFEEGLVSQYKFYLENLEQMVKDWKQRKLKKSNVVSLKAYKGLAEVAVKSLCELLVALPHFNFHNNIIVLIVPLMND---MSKLISEMCCEAVKKLFKQDKLGQASLGVIKVISGFVKGRNYEVRPEMLKTFLCLRIKEVEVKKDTEDINKPKKFMTFKEKRKSLSRMQRKWKKAEEKLERELREAEASESTEKKLKLHTETLNIVFVTYFRILKKAQRSPLLPAVLEGLAKFAHLINVEFFDDLLVVLHTLIESGD------LSYQESLHCVQTAFHILS-GQGDVLNIDPLKFYTHLYKTLFKLHAGATNEG-------------------------VEIVLQCLDVMLTKRRKQVSQQRALAFIKRLCTLALHVLPNSSIGILATTRILMHTFPKTDLLLDSES-QGSGVFLPELDEPEYCNAQNTALWELHALRRHYHPIVQRFAAHLIAGAPSEGSGALKPELSRRSATELFEAYSMAEMTFNPPVESSNPKIKGKFLQGDSFLNEDLNQLIKRYSSEVATESPLDFTKYLKTSLH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRN3-1", "uniprot_id": "NOC3L_DANRE", "id": "Q6DRN3-1", "name": "Nucleolar complex protein 3 homolog", "aln": "MGPASKRNKKKRPSFRKLLKTSNLKLENKLKNRQFKQQSSAKKQRKEQR----KLHKAISDVSHQTLKPLERYK-KRPED--EEEEEEFLESLPTDMMDEDDLEHIRAIAQKASFLTRDLSSCAPVHAKKHKSEQALENYEKMPRKMQQEEEKELIHLLPIKDKSG-LIPQSMEKPVLPQAEEEE-EEPNQEVYLQKEEEPESAP-------------------LLTPQEQFEQRAQKLMEKKLRIAALSSAILADPHVNIKKLKELRAMLMETDPC----VAVTVRKLVMVSLMEVFKDIVPAYRIRPLTEEEKAAKVKKETLQLREFEEGLVSQYKFYLEELEQTVKDWKQKKEKRSQAVSLQSYKGLAEVAVRCICELLVALPHFNFHNNIIVMLVPLMND---SDKKVSEMCCEAVKKLLKQDKVGQASLAMVKVISGMVKSRNYRIKPVVLNCLLCLRIKEVDMKKDTEDTAPKKKFMSFKEKRKNLSRMQRKWKKAEEKLQKELLEAEATESKEKKIKLHTETLNVVFLIYFRILKKAQKSVLLSSVLEGLAKFAHLINLEFFDDLLAVLYNLITSGD------LTYRESLHCILTSFHILS-GQGDVLNIDPLKFYSHLYRTLLTLHAGGVNED-------------------------TVIVLQCLDVMLSKRRKQVTLQRAQAFLKRLNTVALHLLPDSCVGILAANRMLMQTFPKCDILLDNET-QGSGVYLPELDVPEYCNPQNTALWELHLLKSHYHPVVRKFAAHLMKGAPSEGSGALGVELSRRSPLQLFEDYSVKDMSFNPPVAGPPSKKKEYFTIGHAFLHSELSRQIDAALQEEPEQMSLDFTSPHTQQEP--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI82-1", "uniprot_id": "NOC3L_DROME", "id": "Q9VI82-1", "name": "Nucleolar complex protein 3", "aln": "--MGTKKVKISSVKRAAHLKSKKTPLSKQQQQKQKQKRDQLKSKREQGQNIFSQKARKRDNLAQRKKHNKLASLGLDPLEEDNEDGDDEMLENVADMLDGDDLALLQANKRKRKAKTTGENDPD------QGQSIGLERAYASDTKKEQDAQKIKLDLLPIKSRDGQIITRTTEVDYIPKPKQKKKNEEEEEDDSEEDGDTEYEDSDDDVVNDVEAATAAPVQKLISTTDLLIARQQEIERQKYRIGIICSGLLEKPEDKMRNFHALYELMDEINPASRQANLMAVRKLAIISVTEIFKDILPEYRVG--QVDTKMQTLRKATLDRVTFENALLQQFKKFLQKLEQITAQVNRR-----GGLRTPQTVKLATVAVQCMCDLLVAHPYFNYVQNIAQLLVYMLNC---NYAEMRTAVHQCFRTVFSNDKRLEMTLFIVRRINHLIKTKQNNVHVECITCLMGLKIKNVNLDAEKENELKQKKLESHRQRLLSLSKKERKRRKKLTEVNRELEETRAEENKQAKHQKLTEIIKMVFTIYFRVLKNDPTSRVLSAILEGLAEFAHVINLDFFSDLIDVLNRILEDQDE-----LGYRERLHCVQTIFVILS-GQGEVLNIDPIRFYQHFYRNMLAVQAGKNHDD-------------------------FAIILRTLDEVLVKRRRNMSQQRLMAFMKRLLTGSLHLLHNGTLATLGTIKQTFQLTSVLDNLLDTDTTIGSGRYDPELDDPEYCNAASTALYELALLARHYHPTVRRMAVHIAHGVPATGEGALPTEIGKLTSHELFTQFDSTQMAFNPTIPLPKAGQPKLKRGKHLYIRSDFKQEYGKLLQQGKVSQTKDKQTLQIDFFSALQ-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07896-1", "uniprot_id": "NOC3_YEAST", "id": "Q07896-1", "name": "Nucleolar complex-associated protein 3", "aln": "-------------------------MAKRNRSQFRIQERTAKKRKHEDS-----------------------------------LLEGNVFQNAPEDMDENTIYSAKG----------------------SSWDEEEQDYEMVPRKNRSDTSN-LVEGLPIK-VNGKVERKLHKAQEKPKDDDEEDEDSNDSSEDDEGPNEEQE---------------------AEAKEDEPDTEEKILQLKEDIADLVTKVMEEPEENTAALGRLCKMVESKNPN--------TCKFSMLALVPVFKSIIPGYRIRPLTETEKKEKVSKEVSKLRNFEQALVYNYKNYVGRLQSLSK---------TPSNAAPIQVSLGILATQAAKELISTASHFNFRTDIFTLLLRRICKPRISTDPTSIQIIQTFETLLNEDEEGSISFEILRIFNKILKTRNFNIEESVLNMLLSLDVLH-DYDPNTKLKGNVSAPKLKKKDRVHLSKKQRKARKEMQQIEEEMRNAEQAVSAEERERNQSEILKIVFTIYLNILKNNAKT-LIGSVLEGLTKFGNMANFDLLGDFLEVMKELISDTEFDNLSSAEVRKALLCIVSAFSLISNTQYMKVNVDLSKFVDGLYALLPYICLDADIELSYRSLRLADPLNNEIIKPSVNVSTKAELLLKALDHVFFRS-KSGTKERATAFTKRLYMCISHTPEKTSIAILKFIDKLMNRYPEISGLYSSEDRIGNGHFIMEADNPSRSNPEAATLWDNALLEKHYCPVVTKGLRSLSSRSKECSK----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :.: :. *. :.: : : :* : : : . : . . .: :. **** .* : : : .::: : : . : : : ::: * *. : : :: .*. : : * :: . :* . *: :::: :**.* * *:: * . * . . **:.*: ::* :: .*:. *. :*.:. :*: : .:**: :* ::: : : ...::.:*: . :: ::: :. ::* :: .:. :. :: * : . : . :.: . :: **: :** :* :::.*: ::. . : : : :* :::** *:.:**: : :: ::****::*.:: *.:::.*:: *: :: . : :: * *: : * ::* * :*:* :* :* : : . : ::*: ** :: : :. : :* ** *** : . :. * :: . . * ..: *.* : * : *. .*. ::*:: * ** * * : : .. ", "identical_positions": 85, "similar_positions": 227, "identity": "9.7%" }, { "cls_id": "homologset.agr.MGI:1932622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L6W5-1", "uniprot_id": "A0ABK0L6W5_RAT", "id": "A0ABK0L6W5-1", "name": "", "aln": "MSSLAVRDPAMDRS--LRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDS---PYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSH---QEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQPVSGPGPGGPGGPGGPGGPGPGPAPGLCPGPNVMLNQQNP-APQPQHLPRRPVKDIPPLMQTSIQGGIPAPGP-IPAAVPGPGPGS-LTPGGTMQPQVGMPVVGPVPLERGQMQISDPRPPMPRGPMPSGGIPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYMGPPHQGPPMHHG--HDNRGPASHDMRGGPLAADPRMLIGEPRGPMMDQRGLPMDGRGGRDSRGMEARPMETEVLEPRGMERR-METCAMETRGMEARGIDARGLEMRGPGPSSRGPMTGGIQGPGPINMGAGGP-QGPRQVPNIAGVGNPGGAMQGAGIQGAGMQGAGMQGGGMQGAGMQGGGMQGAGMQG--------GGMQGAGMQGASKQGAGQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C7E9-1", "uniprot_id": "CSTFT_MOUSE", "id": "Q8C7E9-1", "name": "Cleavage stimulation factor subunit 2 tau variant", "aln": "MSSLAVRDPAMDRS--LRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDS---PYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSH---QEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQPVSGPGPGGPG-PSGPGGPGPGPAPGLCPGPNVMLNQQNPPAPQPQHLPRRPVKDIPPLMQTSIQGGIPAPGP-IPAAVPGPGPGS-LTPGGAMQPQVGMPVVGPVPLERGQMQISDPRPPMPRGPMPSGGIPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYMGPPHQGPPMHHG--HDNRGPASHDMRGGPLAADPRMLIGEPRGPMIDQRGLPMDGRGGRESRGMETRPMETEVLEPRGMERR-METCAMETRGMDAR-----GLEMRGPGPSSRGPMTGGIQGPGPINMGAGGP-QGPRQVPNIAGVGNPGGTMQGAGIQGGGMQGAGMQGGGMQGAGMQGGGMQGAGMQAGMQGASMQGGMQGAGMQGASKQGGGQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0L4-1", "uniprot_id": "CSTFT_HUMAN", "id": "Q9H0L4-1", "name": "Cleavage stimulation factor subunit 2 tau variant", "aln": "MSSLAVRDPAMDRS--LRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDS---PYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSH---QEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVS------------VSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGP-IPAAVPGAGPGS-LTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLG-DPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQG-------------GGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VE52-1", "uniprot_id": "Q9VE52_DROME", "id": "Q9VE52-1", "name": "", "aln": "MADKAQEQSIMDKS--MRSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGYEIGGRTLRVDNACTEKSRMEMQQL-LQGPQVEN---PYGEPCEPEDAPELITKTVASLPPEQMYELMKQMKLCIVSNP---SEARQMLMLNPQLAYALLQAMVVMRIVDPQQALGMLFKANQMPPVLGGN--------------------------PHQGPGNHTMMGQQQVPQQQVQ---------IPQQQQQAPQPPMPVPGPGFPANVHPNDIDLRMVPGGPMP-------MDPRMMGRG--MDQDLRASLPN-PVPPPLMDPR-----------------ARAQMPPQQQQGVP-QAPPAPYP--------------------------SDPR-----QR--PMDPR---------LR------------------------------------------------------AGPGPQQQ---APPQGIPQAP-------PPTQQQ-----------------------------------------------QAAAQQLQSRLG-------AHGVLPSDASDQEKAALIMQVLQLSDEQIAQLPSEQRVSIVMLKEQIAKSTQR--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25299-1", "uniprot_id": "RNA15_YEAST", "id": "P25299-1", "name": "mRNA 3'-end-processing protein RNA15", "aln": "MNRQSGVNAGVQNNPPSRVVYLGSIPYDQTEEQILDLCSNVGPVINLKMMFDPQTGRSKGYAFIEFRDLESSASAVRNLNGYQLGSRFLKCGYSSNSDISGVSQQQQQQYNNINGNNNNNGNNNNNSNGPDFQNSGNANFLSQKFPELPSGIDVNINMTTPAMMISSELAKKPKEVQLKFLQKFQEWTRAHPEDAVSLLELCPQLS------------------------------------------------------------------------------------------------------------FVTAELLLTNGICKVDDLIPLASRPQEEASATNNN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVNEVVDPAVLNKQKELLKQVLQLNDSQISILPDDERMAIWDLKQKALRGEFGAF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :. ::.. * *::*.***: ***:: :: *:**.*:.:::::* ::*:.**:.* *::* *:: **:***** ::..* *: . :.... :. ::. *: : .:.*: . *.: .::: ** . :.: : . : :: :: :** .*: *: :* ::. : .* .* . .. . . : . . ::: *: *****. .**: ** ::* :* **:: :. ", "identical_positions": 57, "similar_positions": 108, "identity": "8.73%" }, { "cls_id": "homologset.agr.MGI:1932682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BSU2-1", "uniprot_id": "CXL16_MOUSE", "id": "Q8BSU2-1", "name": "C-X-C motif chemokine 16", "aln": "MRRGFGP---LSLAFFLFLLALLTLPGDGNQGSVAGSCSCDRTISSGTQIPQGTLDHIRKYLKAFHRCPFFIRFQLQSKSVCGGSQDQWVRELVDCFERKECGTGHGKSFHHQKHLPQASTQTPEAAEGTPSDTSTPAHS-----QSTQHSTLPSGALSLNKEHTQPWEMTTLPSGYGLEARPEAEANEKQQDDRQQEAPGAGASTPAWVPVLSLLAIVFFLTAAMAYVLCNRRATQ--QNSAGLQLWYTPVEPRP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXU5-1", "uniprot_id": "CXL16_RAT", "id": "Q6AXU5-1", "name": "C-X-C motif chemokine 16", "aln": "MRRGFGP---LALTLFLFFFALLTLPGDGNQGSVAGSCYCDRTIPSGTQIPPATLNHMRKYLKTFHRCQFFIRFQLQSKSVCGGSQDQWVRELVNCFEHKQCGIGHGQSFHHQKHVPQASTRIPEATEGKPPDTSTAVQF-----QSTQQSTFPSGAPSLNKELTRHWETTILPSGYGLEARPVAEANEKQ--HKQQKEPGAGAGTQALVPVLSLLAIVFFLVAAMVCVLCNRRVTR--QSSSGLQLCYTPVEPRPQGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2A7-1", "uniprot_id": "CXL16_HUMAN", "id": "Q9H2A7-1", "name": "C-X-C motif chemokine 16", "aln": "MGRDLRPGSRVLLLLLLLLLVYLTQPGNGNEGSVTGSCYCGKRISSDSPPSVQFMNRLRKHLRAYHRCLYYTRFQLLSWSVCGGNKDPWVQELMSCLDLKECGHAYSGIVAHQKHLLPTSPPISQASEGASSDIHTPAQMLLSTLQSTQRPTLPVGSLSSDKELTRPNETTIHTAGHSLAAGPEAGENQKQ----PEKNAGPTARTSATVPVLCLLAIIFILTAALSYVLCKRRRGQSPQSSPDLPVHYIPVAPDSNT-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.: * : * ::*:::. ** **:**:***:*** *.: *.*.: . ::::**:*:::*** :: **** * *****.:* **:**:.*:: *:** .:. . ****: :*. .:*:** ..* *..: ****:.*:* *: * :** *: * * .:*:.* * * * *:** :: .*. * * * ****.****:*:*.**: ***:** : *.*..* : * ** * . ", "identical_positions": 104, "similar_positions": 78, "identity": "40.15%" }, { "cls_id": "homologset.agr.MGI:1932697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2Q5-1", "uniprot_id": "LTOR2_HUMAN", "id": "Q9Y2Q5-1", "name": "Ragulator complex protein LAMTOR2", "aln": "--------------------------------MLRPKALT-------------------------------------------------QVLSQANTGG---------------------VQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCM--------------------------EGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLTQVAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHS3-1", "uniprot_id": "LTOR2_MOUSE", "id": "Q9JHS3-1", "name": "Ragulator complex protein LAMTOR2", "aln": "--------------------------------MLRPKALT-------------------------------------------------QVLSQANTGG---------------------VQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDSLKFILMDCM--------------------------EGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLTQVAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1B0GWT7-1", "uniprot_id": "A0A1B0GWT7_RAT", "id": "A0A1B0GWT7-1", "name": "", "aln": "PESGASSQPHSAPPCRRPAARQPAQLLLLLLLLARPARLGSGASNSPSRPSPRLRRPLRTAAATAPRAAWGGTAVGAARARAGCAAGPGRIVRPAQRAGDSGPPAVPSRLDKGLSVSPSHLRSPRLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDSLKFILMDCMDQRNPGEGRNQGCQAECPSVLCHSHQEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLTQVAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DEG4-1", "uniprot_id": "LTOR2_DANRE", "id": "Q6DEG4-1", "name": "Ragulator complex protein LAMTOR2", "aln": "--------------------------------MLRPKALT-------------------------------------------------QVLSQANTSG---------------------VQSTLLLNNEGSLLTYSGYGDTDARVTAAIASNIWAAYDKNGHQAFNEDKLKFILMDCM--------------------------EGRVAITRVANLLLCMYAKETVGFGMLKAKAEALVQYLEEPLTQVAAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V8I2-1", "uniprot_id": "LTOR2_DROME", "id": "Q9V8I2-1", "name": "Ragulator complex protein LAMTOR2 homolog", "aln": "--------------------------------MLKPKALT-------------------------------------------------QVLSQANTGG---------------------VENTLLLSQEGALLAYSGYGDKDARITAAIASNIWAAYEKHGRNAFREGRLTFVLIDCEN--------------------------GHVAITQVASVLLCLYAKQTVGLGLLKQKAMSLASYLERPLKQISAS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* * ::: *: .* :... **.:**:**:******.***:************:::*.:**.*. *.*:*:** *:****:**.:***:***:***:*:** ** :*..***.**.*::**", "identical_positions": 70, "similar_positions": 42, "identity": "27.67%" }, { "cls_id": "homologset.agr.MGI:1932723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MI6-1", "uniprot_id": "GIMA3_MOUSE", "id": "Q99MI6-1", "name": "GTPase IMAP family member 3", "aln": "-----METLQN-----------------VVTGGKKGGCTSGSRPLRILLVGKSGCGKSATGNSLLRRPAFESRLRGQSVTRTSQAETGTWEGRSILVVDTPPIFESKAQNQDMDKDIGDCYLLCAPGPHVLLLVTQLGRFTAEDVMAVRMVKEVFGVGVMRHMIVLFTRKEDLAEKSLEEFVTHTDNRSLRSLVQECGRRYCAFNNRASGEEQQGQLAELMALVRRLEQECEGSFHSNDLFLHAETLLREGYSVHQEAYRCYLAKVRQEVEKQRWELEEQEGSWVLKVLP---IGKKLEVLHSDFCWYLVLAILIFFVFFFLLFYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K3L6-1", "uniprot_id": "GIMA5_RAT", "id": "Q8K3L6-1", "name": "GTPase IMAP family member 5", "aln": "MEDHGFEELSTRTHDLNVRRLTKGNINFLLSTGQETYSVEDSGLLRILLVGKSGCGKSATGNSILRRPAFESRLRGQSVTRTSQAEMGTWEGRSFLVVDTPPIFESKIQNQDMDKDIGNCYLMCAPGPHVLLLVTQLGRYTVEDAMAVRMVKQIFGVGVMRYMIVLFTHKEDLADESLEEFVTHTGNLDLHRLVQECGRRYCAFNNKASGEEQQGQLAELMALVRRLEQEHEGSFHSNDLFVYTQVFLRGGYSEHQEPYKFYLTKVRQEVEKQKRELEEQEGSWMAKMLCRVTSCLDWHIAVSVLLIVLGLTLLITLINMYIGRWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96F15-1", "uniprot_id": "GIMA5_HUMAN", "id": "Q96F15-1", "name": "GTPase IMAP family member 5", "aln": "MGGFQRGKYGT-----------------MAEGRSEDNLSATPPALRIILVGKTGCGKSATGNSILGQPVFESKLRAQSVTRTCQVKTGTWNGRKVLVVDTPSIFESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGRFTAQDTVAIRKVKEVFGTGAMRHVVILFTHKEDLGGQALDDYVANTDNCSLKDLVRECERRYCAFNNWGSVEEQRQQQAELLAVIERLGREREGSFHSNDLFLDAQLLQRTGAGACQEDYRQYQAKVEWQVEKHKQELRENESNWAYKALLR--VKHLMLLHYEIFVFLLLCSILFFIIFLFIFHYI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: . ***:****:**********:* :*.***:**.******.*.: ***:**..******.****: :.*:: *:**:***:.********** ****:*.:*.:*:* **::**.*.**::::***:****. ::*:::*::*.* .*: **:** ******** .* ***: * ***:*::.** :* **********: :: : * * . ** *: * :**. :***:: **.*:*..* * * : . : * ::*: :: ::: : ", "identical_positions": 144, "similar_positions": 89, "identity": "44.17%" }, { "cls_id": "homologset.agr.MGI:1932872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LND5-1", "uniprot_id": "A0ABK0LND5_RAT", "id": "A0ABK0LND5-1", "name": "Cystinosin", "aln": "MRGCFAEALGWGWNSLSNQVKLSVRLHFCGMSSLKSGNMMKNWLLILTLFLLKFIERSESTVGLSAPPTVKLVNGSSTNVSITLGHPLNSTLVITFEITFSSKNLTIVELPDEVIVPRGEKNASFQVTSQNIGQVTVYLHGNHSNQTCPR---IQFLVIHSRIVSVINQVIGWIYFMAWSVSFYPQVIQNWRRKSVVGLSFDFLALNLTGFVAYSVFNIGLLWVPYIQEEFLLKYPNGVNPVDINDAFFSLHAVALTLIVILQCCLYERGN--------------QRVSRPSIGFLVLAWLFILVTMIVAAVGVTTWLQFLFCFSYIKLIITLIKYFPQAYMNFYYKSTKGWSIGGVLLDFTGGSFSLLQMFLQSYNND--QWTLIFGDPTKFGLGVFTIFFDIVFFIQHFYLYRK--KPGLQAAPTGFDSHPSQN-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57757-1", "uniprot_id": "CTNS_MOUSE", "id": "P57757-1", "name": "Cystinosin", "aln": "--------------------------------------MRRNWLLILTLFLLMFIEKYESTVSLTAPPTVKLENGSSTNVDITLGHPLNSTLVITFEVTFRSKNLTIVELPDEVIVPRGEKNASFQVTSQNIGQVTVFLHGNHSNQTCPR---IRFLVIHSRIVSIINQVIGWIYFMAWSVSFYPQVIQNWRRKSVIGLSFDFLALNLTGFVAYSVFNIGLLWVPYIQEEFLLKYPNGVNPVDSNDAFFSLHAVALTLIVILQCCLYERGN--------------QRVSWPSIGFLVLAWLFVLVTMIVAAVGITTWLQFLFCFSYIKLIITLIKYFPQAYMNFYYKSTKGWSIGGVLLDFTGGSFSLLQMFLQSYNND--QWTLIFGDPTKFGLGVFTIFFDVVFFIQHFYLYRK--KPGYDQLN-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60931-1", "uniprot_id": "CTNS_HUMAN", "id": "O60931-1", "name": "Cystinosin", "aln": "--------------------------------------MIRNWLTIFILFPLKLVEKCESSVSLTVPPVVKLENGSSTNVSLTLRPPLNATLVITFEITFRSKNITILELPDEVVVPPGVTNSSFQVTSQNVGQLTVYLHGNHSNQTGPR---IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVAYSVFNIGLLWVPYIKEQFLLKYPNGVNPVNSNDVFFSLHAVVLTLIIIVQCCLYERGG--------------QRVSWPAIGFLVLAWLFAFVTMIVAAVGVTTWLQFLFCFSYIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNND--QWTLIFGDPTKFGLGVFSIVFDVVFFIQHFCLYRK--RPGYDQLN-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCR7-1", "uniprot_id": "CTNS_DROME", "id": "Q9VCR7-1", "name": "Cystinosin", "aln": "---------------------------------MDFSTHRLTTLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANG-LLDSDVEVALGT--DSEDHLLLDPATFVYPAGSTRNQSVVITGLKAGNVKVVADSDDANKEIVKDVFVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFTLYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQ--------------QRVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRRKSTSGWSIGNILLDFTGGTLSMLQMILNAHNYD--DWVSIFGDPTKFGLGLFSVLFDVFFMLQHYVFYRHSRESSSSDLTTVTDVQNRTNESPPPSEVTTEKY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17261-1", "uniprot_id": "ERS1_YEAST", "id": "P17261-1", "name": "Cystine transporter", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSLDDILGIVYVTSWSISMYPPIITNWRHKSASAISMDFVMLNTAG---YSYLVISIFLQLYCWKMTGDESDLGRPKLTQFDFWYCLHGCLMNVVLLTQVVAGARIWRFPGKGHRKMNPWYLRILLASLAIFSLLTVQFMYSNYWYDWHNSRTLAYCNNLFLLKISMSLIKYIPQVTHNSTRKSMDCFPIQGVFLDVTGGIASLLQLIWQLSNDQGFSLDTFVTNFGKVGLSMVTLIFNFIFIMQWFVYRSRGHDLASEYPL-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::* :*. :**:*:** : *:*:**. .:.:**: ** .* ** : .: : . * : * :.**. . : : * * *: : .:: : : . : * : :*: ::::**.**. * ** . :.* .::**.*** *:**:: : * : . :. : *.**.:.::.*:..*::* : : . . ", "identical_positions": 50, "similar_positions": 81, "identity": "11.14%" }, { "cls_id": "homologset.agr.MGI:1932915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q803Q2-1", "uniprot_id": "NDL1B_DANRE", "id": "Q803Q2-1", "name": "Nuclear distribution protein nudE-like 1-B", "aln": "MDTEMMPKFSSKDEEIDYWKCLSLKYKKSCHDAQEELQEFQEGSRELEAELEAQLGQAEHRIRDLQSENQRLKSEVDILKEKLEQQYAQSYKQISMLEDDLLQTRGIKEQLHKYVRELEQANDDLERAKRATITSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERTSDVTRMSAPSSPTLDIDKTDSAVQASLSLPATPVGKTMEHPFIGTKALTNGCGNGSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQAARKNYTT--GNGNLINSNATKFSHSLHTTYFDKT-TMNGLDPGALSAAIASPRAVSPPGLLPLSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7SXI6-1", "uniprot_id": "NDL1A_DANRE", "id": "Q7SXI6-1", "name": "Nuclear distribution protein nudE-like 1-A", "aln": "MDADMIPKFTTKEEEIDFWKALSLKYKKSYKEAQEELLEFQEGSRELETELETQLGQAEHRIRDLQADNQRLQHELDSLKEKLEYQYAQSYKQISVLEDDLSQTRGIKEQLHKYVRELEQANDDLERAKRATITSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRDTRSEVTRMSAPSSPTPDNDKTDSAVQASLSLPATPLSKNLDNAFTSQTVLANGSTN-AALTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQAARKNYVTN-VNGNLINGDISNYSHSLHTSYFDKARTVNGLDPGDGTHITAPPRSNSPSGLV-LSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q78PB6-1", "uniprot_id": "NDEL1_RAT", "id": "Q78PB6-1", "name": "Nuclear distribution protein nudE-like 1", "aln": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGT-SPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYVPGSVNCGVMNSNGPECPRSGRATFFHKG-AVNGFDPAPPPPGLGSSRPSSAPGMLPLSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERR1-1", "uniprot_id": "NDEL1_MOUSE", "id": "Q9ERR1-1", "name": "Nuclear distribution protein nudE-like 1", "aln": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGT-SPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYVPGSVNCGVMNSNGPECPRSGRATFFHKG-AVNGFDPAPPPPGLGSSRPSSAPGMLPLSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZM8-1", "uniprot_id": "NDEL1_HUMAN", "id": "Q9GZM8-1", "name": "Nuclear distribution protein nudE-like 1", "aln": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFGT-SPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNGTKFSRSGHTSFFDKG-AVNGFDPAPPPPGLGSSRPSSAPGMLPLSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT70-1", "uniprot_id": "NDE1_DROME", "id": "Q9VT70-1", "name": "Nuclear distribution protein nudE homolog", "aln": "--MESPPMFNSVEDECRYWKERSKQYHKEWTDVKQEYDEFVEQSREMEIEMDATLDQKQSIIKDLTAKLTMFERENESLKLKLESHGID----MSNMEKQLETVKKDRDTMKVYLRQLEQKNDDLERAHRILNESIENFEKMLDQAYEKNALLELEVDEKGLLQEKLQRLMDETRDLKQELNVKSRFTPVVNGTSVPTAN-DTNTVNSSMNSSASLPNGIVANGELVKHDN------------AVATRATSVSVNALNGSLVNRNEYNQQHSLKSDGDETEDVPREWSANAAATPLLP--AIHTSGAGRTALLLAGCRVVWILQFSVIHKPQIRNPIT---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *.: .:* :** * :*::. :.::* ** * ***:* *::: * * : :** :. :: * : ** *** : : :* :*.:* .: :: :: *:*:*** *******:* *:*:**: *:** *:**:** *:*** * .:*** **:***:*** *:. *.. :: .:.. * :. :*::::* *** :.: . . .::. * ::* :.. * : . :.: : : : : :.: . :: . . : ::: : : : .. : ", "identical_positions": 81, "similar_positions": 109, "identity": "23.34%" }, { "cls_id": "homologset.agr.MGI:1932970", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924A4-1", "uniprot_id": "UCN3_MOUSE", "id": "Q924A4-1", "name": "Urocortin-3", "aln": "MLMPTYFLLPLLLLLGGPRTSLSHKFYNTGPVFSCLNTALSEVKKNKLEDVPLLSKKSFGHLPTQDPSGEEDDNQTHLQIKRTFSGAAGGNGAGSTRYRYQSQAQHKGKLYPDKPKSDRGTKFTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQIGKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1YKY5-1", "uniprot_id": "A1YKY5_RAT", "id": "A1YKY5-1", "name": "", "aln": "MLMPTYFLLLLLLLLGGPRTSLSHKFYNAGPVFSCLNTALSEVKKNKLEDVPVLSKKNFGYLPTQDPSGEEEDEQKHIKNKRTFSDAVGGNGGRSIRYRYQSQAQPKGKLYPDKVKNDRGTKFTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQIGKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969E3-1", "uniprot_id": "UCN3_HUMAN", "id": "Q969E3-1", "name": "Urocortin-3", "aln": "MLMPVHFLLLLLLLLGGPRTGLPHKFYKAKPIFSCLNTALSEAEKGQWEDASLLSKRSFHYLRSRDASSGEEEEG---KEKKTFPISGARGGARGTRYRYVSQAQPRGKPRQDTAKSPHRTKFTLSLDVPTNIMNLLFNIAKAKNLRAQAAANAHLMAQIGRKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.:*** **********.*.****:: *:**********.:*.: **..:***:.* :* ::*.*. *::: : *:**. : . .*. . **** **** :** *. *. : ***************:**** *******:*****:******:**", "identical_positions": 99, "similar_positions": 40, "identity": "60.37%" }, { "cls_id": "homologset.agr.MGI:1933105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FWT7-1", "uniprot_id": "UBCP1_RAT", "id": "Q5FWT7-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "---MSLPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLCPPPDNDDVINDFDIEDEVVE-VENREENLLKISRRVKEYKVEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAK-LDDFLELNHKYWERYLSKKQGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGR9-1", "uniprot_id": "UBCP1_MOUSE", "id": "Q8BGR9-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "---MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLCPPPDNDDVINDFDIEDEVVE-VENREENLLKVSRRVKEYKVEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAK-LDDFLELNHKYWERYLSKKQGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVY7-1", "uniprot_id": "UBCP1_HUMAN", "id": "Q8WVY7-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "---MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVE-VENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAK-LDDFLDLNHKYWERYLSKKQGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DI37-1", "uniprot_id": "UBCP1_DANRE", "id": "Q6DI37-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "---MSVSVIIKWGGQEYSINTLSEEDTVLDLKQSIKSLTGVLPERQKLLGLKLKGKPADDNVKLGDLKLKPNTKIMMMGTREESLEDVLAPPPENDDVVNDFDIEEEVTE-VENREENLAKIARRVKDYKVEELNPPRPGKRLLVLDIDYTLFDHKSCAETGHELMRPFLHEFLTSAYEDFDIVIWSATSMKWIDAKMKELGVTDNPNYKITFMLDSAAMITVHTPKRGVVEVKPLGVIWGKYSEFYNRKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNREKDKELYKLSQYLKEIAK-LDDFSGLNHKHWERYLSKKQNQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ16-1", "uniprot_id": "UBCP1_DROME", "id": "Q9XZ16-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "MEVKEVVVIVKWSGKEYPVD-LTDQDTVEVLRHEIFRKTQVRPERQKLLNLKYKGKTAADNVKISALELKPNFKLMMVGSTEADIEDACSLPDNIGEVVDDFDDADEREESVEHSAVYLAKVQRRVRDYKIKELAPPREGKKLLVLDIDYTLFDHRSPAETGTELMRPYLHEFLTSAYEDYDIVIWSATSMRWIEEKMRLLGVASNDNYKVMFYLDSTAMISVHVPERGVVDVKPLGVIWALYKQYNS-SNTIMFDDIRRNFLMNPKSGLKIRPFRQAHLNRGTDTELLKLSDYLRKIAHHCPDFNSLNHRKWEHYHPKKNS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*:**.*:**.: *:::*** *:: : * * *******.** ***.* ::**:. *:**** *:**:*: * .:**. * : .:*::*** :* * **: * *: ***::**:: * *** **:*****:*******:* **** *****:***********:********.*:**: **: ***: * ***: * ***:***:**.*.**:::********. :.:: . .******** *******:.******* :***** .*.** **::**::**: ** ***: **:* .**:. ", "identical_positions": 181, "similar_positions": 78, "identity": "56.04%" }, { "cls_id": "homologset.agr.MGI:1933107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIS2-1", "uniprot_id": "CPTP_RAT", "id": "Q5XIS2-1", "name": "Ceramide-1-phosphate transfer protein", "aln": "------------MDGPERDFNLKVVLISFKKCLTDKGEVLLDHYTASWKGLVRFLNSLGAVFSFISKDVVSKLQIMEHLRS--GPQSEHYISLQSMVAYEVSNKLVDRDSRSRPRHPNSGCRTVLRLHRALHWLQLFLEGLRTSSEDARTSTLCSEAYNATLAAYHSWIVRQAVNVAFHALPPRKVFLEAMNMGSSEQAVEMLGEALPFIEQVYDISQKLYAEHSLLDLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BS40-1", "uniprot_id": "CPTP_MOUSE", "id": "Q8BS40-1", "name": "Ceramide-1-phosphate transfer protein", "aln": "------------MDDSEKDFNLKVVLVSFKQCLTDKGEVLLDHYIAGWKGLVRFLNSLGAVFSFISKDVVAKLQIMERLRS--SPQSEHYASLQSMVAYEVSNKLVDMDHRSHPRHPHSGCRTVLRLHRALHWLQLFLDGLRTSSEDARTSTLCSEAYNATLANYHSWIVRQAVTVAFCALPSRKVFLEAMNMESTEQAVEMLGEALPFIEHVYDISQKLYAEHSLLDLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TA50-1", "uniprot_id": "CPTP_HUMAN", "id": "Q5TA50-1", "name": "Ceramide-1-phosphate transfer protein", "aln": "------------MDDSETGFNLKVVLVSFKQCLDEKEEVLLDPYIASWKGLVRFLNSLGTIFSFISKDVVSKLRIMERLRG--GPQSEHYRSLQAMVAHELSNRLVDLERRSH--HPESGCRTVLRLHRALHWLQLFLEGLRTSPEDARTSALCADSYNASLAAYHPWVVRRAVTVAFCTLPTREVFLEAMNVGPPEQAVQMLGEALPFIQRVYNVSQKLYAEHSLLDLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBQ8-1", "uniprot_id": "CPTP_DANRE", "id": "Q6DBQ8-1", "name": "Ceramide-1-phosphate transfer protein", "aln": "------------MADA---FSLQRVLETFRSSLSENKEVYIKYYIAGWQELVSFMNSLGNVFSFISKDVVSKIQILENFLS--GENGSNYVTIQSMVKYELENDLVDLTKRGS--HPESGCRTLLRLHRALRWLELFLERLRTSTEDSKTSVMCSDAYNESLANHHPWLIRKAVGVAFCALPGRETFFDVMNAGDHTQVVALLGESLPLIAEVYQITEDLYAKNNLLELP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLW4-1", "uniprot_id": "Q8MLW4_DROME", "id": "Q8MLW4-1", "name": "Glycolipid transfer protein domain-containing protein", "aln": "MSKTSLATQTNGTAENGNCFDILKVSNLFETSLLDEDDVQLDAYLAAYEEIMKFFQLMGSVFSFVSSDVRSKIDILYALRAKDAEEQEHFNTFRTMLDYEKEAQLLTQKGYVS------GSRTLLRLHRGLDFVYEFLNRIQAIPDDQKTVDVCKEAYDDTLGKHHSFLIRKGARLAMYAMPTRGDLLKKVCS-DVEAAKENLPSMLKHMRTNYDRTEDLYTLYDLHSLP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: * *. .* :: :* :. * *.:: :: *:: :* :***:*.** :*: *: : . . : .:: ::::*: :* . *: *.**:*****.* :: **: ::: .:* :* :* ::*: :*. :*.:::*:.. :*: ::* * ::. : . * . * : *: ::.**: .* .**", "identical_positions": 49, "similar_positions": 82, "identity": "21.3%" }, { "cls_id": "homologset.agr.MGI:1933108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSE5-1", "uniprot_id": "A0A8I5ZSE5_RAT", "id": "A0A8I5ZSE5-1", "name": "", "aln": "-----MPGRAGPLFSGGCGSDASAGPKMDLPAVLAAP----------------------------ATRGDQHGGG---------------------------------------PSRLRRG----------TGPSLGAGPGRRRLLLLRSPEDGGPGPR-------------------------QEEAPGPSPPP-------PEDG----------------------------------------------GDSFVVLLEVPR---AADTHEQEETEPDS---GASPT--------------------EQVP---AAAPG------AALAGTVTIHNQDLLVRFDRGVFTLAAAP--------------------------------APATQGLHPATTPGL------------------------------------------------EPSSAAASRRGPVAASAGSPA----------------YRCPEPQCALSFAKKHQLKVHLLTHGSLQGRRPFKCPLDGCGWAFTTSYKLKRHLQSHDKLRPFSCPVGGCGKKFTTVYNLKAHMKGHEQESLFKCEVCAERFPTHAKLNSHQRSHFEPERPYKCDFPGCEKTFITVSALFSHNRAHFREQELFSCSFPGCNKQYDKACRLKIHLRSHTGERPFICDSDSCGWTFTSMSKLLRHKRKHDDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFECPVEGCCARFSARSSLYIHSKKHLQDVGTPKSRCPVSSCNRLFTSKHSMKAHMVRQHSRRQDLVPQLEAPSSLTPSSELSS----------PGQSELTNIDLAALFSDTPANS--SSSTAGSDEALNSGILTIDVTSVSSSLGGNLPTNN-NSLG---PMDPLVLVAHSDMPP-SLDSPLVLGTPATVLQPGSFSADDSQAMSTGAVGCLVALPMRNLS----------------QDSPALTP---------------------SNNLTALGTTPTSSDTTQETASVPDLLVP-IKVEQD--------LSPVPDVVQGQKESHGP--SVLSSSAERLGAQKDSELSAGTGSLYLESGGSARTDYRAIQLVKKKKQKGTGSDEGASDSAHRKIKGSTVSLPHVHSGQHSCFCGNPMAPSGSLPVPAPAAATQC----VQIPVLQPVSLHLCKPLPLLGLTYQDDPSGEGGLPLALSPQRSAFHPYFTVDLPVYVLQEVLPAPGGFAGLEAAQVPGSTINLQDLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8V1-1", "uniprot_id": "ZXDC_MOUSE", "id": "Q8C8V1-1", "name": "Zinc finger protein ZXDC", "aln": "---------------------------MDLPAVLAAP----------------------------ATRGDQHGGG---------------------------------------PSRLRRG----------AGPSLGAGPGRRRLLLLRGPEDGGPGPR-------------------------PEEAPGPSPPP-------PEDG----------------------------------------------GDSFVVLLEVPR---AADTHGQEEAEPDS---GASPT--------------------EQVP---AAAPG------AALAGTVTIHNQDLLVRFDRGVFTLAAAP--------------------------------APAAPSLHPATTPGL------------------------------------------------EPSSAAASRRGPVAASAGSPA----------------YRCPEPQCALSFAKKHQLKVHLLTHGSLQGRRPFKCPLDGCGWAFTTSYKLKRHLQSHDKLRPFSCPVGGCGKKFTTVYNLKAHMKGHEQESLFKCEVCAERFPTHAKLNSHQRSHFEPERPYKCDFPGCEKTFITVSALFSHNRAHFREQELFSCSFPGCNKQYDKACRLKIHLRSHTGERPFICDSDSCGWTFTSMSKLLRHKRKHDDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFECPVEGCCARFSARSSLYIHSKKHLQDVGTPKSRCPVSSCNRLFTSKHSMKAHVVRQHSRRQDLVPQLEAPSSLTPSSELSS----------PGQSELTNIDLAALFSDTPANS--SSSTAGSDEALNSGILTIDVTSVSSSLGGNLPTNN-NSLG---PMDPLVLVAHGDMPP-SLDSPLVLGTSATVLQPGSFSADDSQAMSTGAVGCLVALPVRNLN----------------QDSPALTP---------------------SNNLTAPGTTPTSSDTTQETGSVPDLLVP-IKVEQD--------LSPVPDVVQGQKESHGPSQSVLSSSTERPGAQKDSELSAGTGSLYLESGGSARTDYRAIQLVKKKKQKGTGSDEGASDSAHRKVKGGTINPPHVHSGQHSCFCGTLMVPSGGLTVPAPAAGLQC----VQIPVLQ------------------DDPSGEGGLPLGLSPQRSAFHPYFTVDLPVYVLQEVLPAPGGFAGLETAQVPGSTINLRDLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2QGD7-1", "uniprot_id": "ZXDC_HUMAN", "id": "Q2QGD7-1", "name": "Zinc finger protein ZXDC", "aln": "---------------------------MDLPALLPAP----------------------------TARGGQHGGG---------------------------------------PGPLRRA----------PAP-LGASPARRRLLLVRGPEDGGPGAR-------------------------PGEASGPSPPP-------AEDDSD--------------------------------------------GDSFLVLLEVPHGGAAAEAAGSQEAEPGSRVNLASRP--------------------EQGPSGPAAPPGP----GVAPAGAVTISSQDLLVRLDRGVLALSAPP--------------------------------GPATAG-------------------------------------------------------------AAAPRRAPQASGPSTPG----------------YRCPEPQCALAFAKKHQLKVHLLTHGGGQGRRPFKCPLEGCGWAFTTSYKLKRHLQSHDKLRPFGCPVGGCGKKFTTVYNLKAHMKGHEQESLFKCEVCAERFPTHAKLSSHQRSHFEPERPYKCDFPGCEKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFICDSDSCGWTFTSMSKLLRHRRKHDDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFECPVEGCCARFSARSSLYIHSKKHVQDVGAPKSRCPVSTCNRLFTSKHSMKAHMVRQHSRRQDLLPQLEAPSSLTPSSELSS----------PGQSELTNMDLAALFSDTPANA--SGSAGGSDEALNSGILTIDVTSVSSSLGGNLPANN-SSLG---PMEPLVLVAHSDIPP-SLDSPLVLGTAATVLQQGSFSVDDVQTVSAGALGCLVALPMKNLS----------------DDPLALTS---------------------NSNLAAHITTPTSSSTPRENASVPELLAP-IKVEPD--------SPSRPGAVGQQEGSHGLPQSTLPSPAEQHGAQ-DTELSAGTGNFYLESGGSARTDYRAIQLAKEKKQRGAGSNAGASQSTQRKIKEGKMSPPHFHASQNSWLCGSLVVPSGGRPGPAPAAGVQCGAQGVQVQLVQ------------------DDPSGEGVLPSARGP--ATFLPFLTVDLPVYVLQEVLPSSGGPAGPEATQFPGSTINLQDLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6W7-1", "uniprot_id": "A0ACD6B6W7_DANRE", "id": "A0ACD6B6W7-1", "name": "", "aln": "MEIQGLTDTKNTQYQHGASLNPTFSQQTTASGILARPRLIGKAISDLSGSLDIESDDNNNRARSTPLRVAENGSGCLLSLQNSPHKAYEVQSGDAELGDLNVSKPKVFNELELLPSEFERADEHEDNDLQMALPLLDAENCEQRQATEKIPEDTSASSSRSPEELYVVFNIVHKDKERQTSVQYKAEENGSSASPKSKTLDSPTDSEGSFNRTSSKSAHLSSHNNLNVRSERTDQNARQEVCLVTENRNPVLSEDFAGTCQTPN-ISTGEMLSSSLAEHSTEELMQCVVKNNRLSTDMNEINIMDYANQESSSNGDCGPDGGSIPVHETFSGTIMINNQNIIVTIENGILTLATPPDSYAYKDDGVMSLKEHLGMKDNEDLVLLNYDGGSKSIGKISNVTSSLQDEPKARFANSDSELTLADDCSLSEMGVTLDSCPSIKQEEGSVCAVEDDSSICQNLKRKPLTCEELQPMNLLTVSGMTKKVSLAKYRCPQPGCSSTFDTRQNLKIHLVVHTEDQ--RPFKCTVEGCDWSFTTSYKLKRHLQSHDKVRPYKCEWENCGRRFTTVYNLKAHVRTHDQENAFVCEVCSERFRTATRLSNHQRTHFEPERPHKCEFPGCEKTFITFSALFSHNRTHFREMAQFTCTYPGCDKRYDKACRLKIHLRSHTGERPFVCDSDSCGWTFTSMSKLLRHKRKHDDDRRFACLEEGCGKSFTRAEHLKGHSITHLGTKPFECPVEGCNAKFSARSSLYIHSKKHKQDGVSLRSRCPVAGCTKHFSSRSSLKTHMLKHHNLSPDVLSQLDDAATLTPSSELTSTSQAVSVPSGPAGAELSSLDLSSLFSSIPACTGPTAVSVGSEGSSGPGSFSMDIPLVNTGILTIDPASVGSALTGTKTVDPLILAAGQDIGVHVLDTGLGTGGGGGVLPHAALHLDDVQTVNPEELGTLTALSIQRTPSSEQLHTMNSCNPLTVESPSALTPSLSSSLTQSLSSLTSTLPPTLSCSLVPSLATPLTSVMSLAAAPVQELLSPQVKADLTGSETSVGPLLSRVEVMPQSDGSKGMCQFVFPSHSGSYSGPKITEIPSVTPCPVMESSGSARTDYRAIQLAKRRKQKGSNSSTCASETPQRKTKVSKSTNSALPTNSSAHFGEGAAAGNGELPIRDPVTGTQF----VQIQLLQ------------------DDPAADGDLAFQLSSQTSCSHSQLTVDLPVHILQEPTVLAEDESGSDNSQFTGSTINLQDLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:*. * . * ::*.* *. :.*. . * *.* .:* : *** .... * *.*..* . *. .:.* :.*. :.: .. :* .: . *. . ... * : :*:: * .*:::* ::.*:::*::.* .. : . . :* * :. * ****:* *: :* .:::**:**:.* * *****.::**.*:****************:**: * .**::**********:: *:**. * ****:*** * ::*..***:*******:**:**********.********:**** *:*::***.*:********************:*******************:*********:* ********************************* *:************** ** : :*****: *.: *:*: *:*:*::::*. *::.**: .::*******:* *. :**:.:**::***. ** : :. : **: : ..* :::*:. *.:.: *:. .:* .::**:*.* *: **: * * . ** .:: ** *::.. :* *.**.::. :.. ***. . .*.. :** :* . ..* :** * :*.: . .: .. *:* .:.* : .. :*:.: * :**.************.*.:**:*:.*. **::.:** * .. . . . :.. : : . .* . *.:. * **: ::* ***:.:* *. .. : . :******::*** . . :* : :*..******:**:", "identical_positions": 367, "similar_positions": 271, "identity": "29.22%" }, { "cls_id": "homologset.agr.MGI:1933111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96AK3-1", "uniprot_id": "ABC3D_HUMAN", "id": "Q96AK3-1", "name": "DNA dC->dU-editing enzyme APOBEC-3D", "aln": "--------------------MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGN---RLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAG----ARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNP--------------------------------MEAMYPHIFYFHFKNLL----KACGRNESWLCFTMEVTKHHSAVFRKR--GVFRNQVDPETH----CHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCP--ECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDE-PFKPWKGLQTN---FRLLKRRLREILQ---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IUX4-1", "uniprot_id": "ABC3F_HUMAN", "id": "Q8IUX4-1", "name": "DNA dC->dU-editing enzyme APOBEC-3F", "aln": "--------------------MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRG------------QVYSQPEHHAEMCFLSWFCGN---QLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAARLYYYWERDYRRALCRLSQAG----ARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFLHRTLKEILRNP--------------------------------MEAMYPHIFYFHFKNLR----KAYGRNESWLCFTMEVVKHHSPVSWKR--GVFRNQVDPETH----CHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCP--ECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDE-PFKPWKGLKYN---FLFLDSKLQEILE---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UH17-1", "uniprot_id": "ABC3B_HUMAN", "id": "Q9UH17-1", "name": "DNA dC->dU-editing enzyme APOBEC-3B", "aln": "--------------------MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRG------------QVYFKPQYHAEMCFLSWFCGN---QLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISAARLYYYWERDYRRALCRLSQAG----ARVTIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAFLHRTLKEILR-----------------------------------YLMDPDTFTFNFNNDP----LVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCNEAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGC-PFQPWDGLEEH---SQALSGRLRAILQNQGN-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HC16-1", "uniprot_id": "ABC3G_HUMAN", "id": "Q9HC16-1", "name": "DNA dC->dU-editing enzyme APOBEC-3G", "aln": "--------------------MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPPLDAKIFRG------------QVYSELKYHPEMRFFHWFSKWR--KLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILR-----------------------------------HSMDPPTFTFNFNNEP----WVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCF--SCAQEMAKFISKNKHVSLCIFTARIYDD-QGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGC-PFQPWDGLDEH---SQDLSGRLRAILQNQEN-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60705-1", "uniprot_id": "ABEC3_RAT", "id": "P60705-1", "name": "DNA dC->dU-editing enzyme APOBEC3", "aln": "-----------MGPFCLGCSHRKCYSPIRNLISQETFKFHFKNLRYAIDRKDTFLCYEVTRKDCDSPVSLHHGVFKN----------------KDNIHAEICFLYWFHDKVLKVLSPREEFKITWYMSWSPCFECAEQVLRFLATHHNLSLDIFSSRLYNIRDPENQQNLCRLVQEG----AQVAAMDLYEFKKCWKKFVDNGGRRFRPWKKLLTNFRYQDSKLQEILRPCYIPVPSSSSSTLSNICLTKGLPETRFCVERRRVHLLSEEEFYSQFYNQRVKHLCYYHGVKPYLCYQLEQFNGQ-----APLKGCLLSEKG-------KQHAEILFLDKIRSMELSQ---VIITCYLTWSPCP--NCAWQLAAFKRDRPDLILHIYTSRLYFHWKRPFQKGLCSLWQSGILVDVMDLPQFTDCWTNFVNPKRP--FWPWKGLEII---SRRTQRRLHRIKESWGLQDLVNDFGNLQLGPPMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J72-1", "uniprot_id": "ABEC3_MOUSE", "id": "Q99J72-1", "name": "DNA dC->dU-editing enzyme APOBEC-3", "aln": "MQPQRLGPRAGMGPFCLGCSHRKCYSPIRNLISQETFKFHFKNLGYAKGRKDTFLCYEVTRKDCDSPVSLHHGVFKN----------------KDNIHAEICFLYWFHDKVLKVLSPREEFKITWYMSWSPCFECAEQIVRFLATHHNLSLDIFSSRLYNVQDPETQQNLCRLVQEG----AQVAAMDLYEFKKCWKKFVDNGGRRFRPWKRLLTNFRYQDSKLQEILRPCYISVPSSSSSTLSNICLTKGLPETRFWVEGRRMDPLSEEEFYSQFYNQRVKHLCYYHRMKPYLCYQLEQFNGQ-----APLKGCLLSEKG-------KQHAEILFLDKIRSMELSQ---VTITCYLTWSPCP--NCAWQLAAFKRDRPDLILHIYTSRLYFHWKRPFQKGLCSLWQSGILVDVMDLPQFTDCWTNFVNPKRP--FWPWKGLEII---SRRTQRRLRRIKESWGLQDLVNDFGNLQLGPPMS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NTF7-1", "uniprot_id": "ABC3H_HUMAN", "id": "Q6NTF7-1", "name": "DNA dC->dU-editing enzyme APOBEC-3H", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALLTAETFRLQFNNKRRLRRPYYP-RKALLCYQLTPQNGS-----TPTRGYFENKK--------KCHAEICFINEIKSMGLDETQCYQVTCYLTWSPCS--SCAWELVDFIKAHDHLNLGIFASRLYYHWCKPQQKGLRLLCGSQVPVEVMGFPEFADCWENFVDHEKPLSFNPYKMLEELDKNSRAIKRRLERIKIPG--VRAQGRYMDILCDAEV-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* * :. **: : . * : .: *** *:. . *. :* : :**** ** :: * . .: * *:::*: ::.* * :.:* :* ** .** . * *:. *. . :*. * ", "identical_positions": 35, "similar_positions": 41, "identity": "7.26%" }, { "cls_id": "homologset.agr.MGI:1933112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYA0-1", "uniprot_id": "RIPL2_RAT", "id": "Q6AYA0-1", "name": "RILP-like protein 2", "aln": "MEEPPVREEED--GEEDE--------GALAKSPLQLTTEDVYDISYVVGRELMAL--GSDPRVTRLQFKIVRVMEMLEALVNEGSLAVEELRMERDNLKQEVEGLRRAGVSGS-EVNLGPDKMVVDLTDPNRPRFTLQELRDVLQERNKLKSQLLLVQEELQCYRSGLLPPRE-----TPGGRREKDAMVTMGNGE---KEERTIMKKLFSFRSGKHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LE1-1", "uniprot_id": "RIPL2_MOUSE", "id": "Q99LE1-1", "name": "RILP-like protein 2", "aln": "MEDHPVREEED--GEEDE--------GALAKSPLQLTTDDVYDISYVVGRELMAL--GSDPRVTRLQFKIVRVMEMLETLVNEGSLAVEELRMERDNLKQEVEGLRKAGVSGA-QVNLGPDKMVVDLTDPNRPRFTLQELREVLQERNKLKSQLLLVQEELQCYRSGLLPPRE-----TPGGRREKDAVVAMGNGE---KEERTIMKKLFSFRSGKHT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969X0-1", "uniprot_id": "RIPL2_HUMAN", "id": "Q969X0-1", "name": "RILP-like protein 2", "aln": "MEEPPVREEEEEEGEEDEERDEVGPEGALGKSPFQLTAEDVYDISYLLGRELMAL--GSDPRVTQLQFKVVRVLEMLEALVNEGSLALEELKMERDHLRKEVEGLRRQSPPASGEVNLGPNKMVVDLTDPNRPRFTLQELRDVLQERNKLKSQLLVVQEELQCYKSGLIPPRE-----GPGGRREKDAVVTSAKNAGRNKEEKTIIKKLFFFRSGKQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IGC3-1", "uniprot_id": "RIPL2_DANRE", "id": "A4IGC3-1", "name": "RILP-like protein 2", "aln": "MEG---RHDNS----PTQ---------AFDKDVLELTVEDVYDISYVIGRDLLKVNTGGNREISDLQFKIVRVLEMFETMVNKYNLSLEELRMEMDNMRTETDRVVAEGSSGN-INTVGPNKLVVDLKDPNRPRFTMQELKEVLQERNKLKAQLLVAQEELQLYKSGVLSSQQNMVEVNLETVPQSEPLRSSITEE---SKEKSTIQKLFSFRPK---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.::. : *: *. ::**.:*******::**:*: : *.: .:: ****:***:**:*::**: .*::***:** *::: *.: : . .. .:**:*:****.********:***::*********:***:.***** *:**::..:: :.:.: : . .:*:: ::*** **. ", "identical_positions": 82, "similar_positions": 72, "identity": "37.61%" }, { "cls_id": "homologset.agr.MGI:1933113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99LE2-1", "uniprot_id": "GP146_MOUSE", "id": "Q99LE2-1", "name": "G protein-coupled receptor 146", "aln": "MWSCGPLNSTAWAEE-PLCRNLRLGLWVLSLLYLGAGVPVSLGYNALLVLANLASKNTMTMPDVYFVNMAVAGLVLTALAPAYLLGPAHSRWALWSLSSEAHVTLLILFNVASLVTMYSTALLSLDYYIERALPRTYMASVYNTRHVCGFVWGGAVLTSFSSLLFYICSHVSSRIAECARMQNTEAADAILVLIGYVVPGLAVLYALALISRIGKEDTPLDQDTSRLDPSVHRLLVATVCTQFGLWTPYYLS-LGHTVLTSRGRTVEGHYLGILQVAKDLAKFLAFSSSSVTPLLYRYINKAFPGKLRRLMKKMHCGRRHCSPDPSGIQQVMAQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZIS6-1", "uniprot_id": "D3ZIS6_RAT", "id": "D3ZIS6-1", "name": "G-protein coupled receptor 146", "aln": "MWSCGPLNSTAWAEE-PLCRNLRLGLWVLSLFYLGAGVPVGLGYNALLVLANLASKNSMTMPDVYFVNMAVAGLVLTALAPAYLLGPAHSRWALWSLSSEAHVTLLILFNVASLVTMYSTALLSLDYYIERALPRTYMASVYNTRHVCGFVWGGAVLTSFSSLLFYICSHVSSRIAECARMQNTEAADAILVLIGYVVPGLAVLYALALISRIGKEDTPLDQDTSRLDPSVHRLLVATVCTQFGLWTPYYLS-LGHTVLVSRGRTVEGHYLGILQVAKDLAKFLAFSSSSVTPLLYRYINKAFPSKLRRLVKKIHCGRRHCSPDPAGIQQVMAQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96CH1-1", "uniprot_id": "GP146_HUMAN", "id": "Q96CH1-1", "name": "G protein-coupled receptor 146", "aln": "MWSCSWFNGTGLVEELPACQDLQLGLSLLSLLGLVVGVPVGLCYNALLVLANLHSKASMTMPDVYFVNMAVAGLVLSALAPVHLLGPPSSRWALWSVGGEVHVALQIPFNVSSLVAMYSTALLSLDHYIERALPRTYMASVYNTRHVCGFVWGGALLTSFSSLLFYICSHVSTRALECAKMQNAEAADATLVFIGYVVPALATLYALVLLSRVRREDTPLDRDTGRLEPSAHRLLVATVCTQFGLWTPHYLILLGHTVIISRGKPVDAHYLGLLHFVKDFSKLLAFSSSFVTPLLYRYMNQSFPSKLQRLMKKLPCGDRHCSPDHMGVQQVLA--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****. :*.*. .** * *::*:*** :***: * .****.* ********** ** :******************:****.:****. *******:..*.**:* * ***:***:**********:****************************:****************:* ***:***:***** **:******.**.****.*:**: :******:**.**:**.*****************:** *****: ***:.*:.****:*:..**::*:****** ********:*::**.**:**:**: ** ****** *:***:* ", "identical_positions": 246, "similar_positions": 62, "identity": "73.43%" }, { "cls_id": "homologset.agr.MGI:1933114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJW6-1", "uniprot_id": "A0A8I6GJW6_RAT", "id": "A0A8I6GJW6-1", "name": "", "aln": "MCREPPSQTTPLSLNLTHIPQSPCSSTEYLAGPWARTGVVAPLCVGAMRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQG----PTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAK-EVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDD-KPIGATHNCNVADPAMVAPQLGPGQTAQLPLSENSAPGPQHGPPPGLRPDVPGGGGGG--VPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAP---KVPPTPEPLP-LNTPSAGTPQSQPPPLPPPPP-APGSAP-PALPQEGPPEDTSQDLAPNSVGAASTGG-------GTGGTHPNTPTAATANNPLPPGGDPGS------APGSALLGEATPTGNGQRNLVG-SEGLSKEQLEHRERSLQTLRDIERLLLRSGE--TEPFLKGPPG---------------------GAVEGGPPAQAPSAAQQPPSAPPPG-LKKYEEPLQSMISQTQSLGGPPLEHEVPG-----HPQGGDMGQQMNMMMQ-RLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGG-----MMGRGPPPPYHSKPGDQ-WPPGMGTQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSIP---MEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQTHRQMDPTMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMAGPQKMLMPS-----QFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGAVGTARLSHMPLPPASNPPGSVHSAPNRGLGRRPSDLTISINQMGSPGMG---HLKSPTLSQVHSPLVTSPSAN-LKSP----QTPSQMVPLPSANPPGP-----LKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNINSSSTLGNLEQGALPPAGPRNSSSAPPANPPSSLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNP-------AAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGPSQNSMMMAPGGPDSLNTPCGPVPSSSQ-MMSFPPRLQQPHGAMAATGGGG--PGLQQHYPSGMALPPEDLPNQPPGPIPSQQHLMGKGMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKNENQ------PPKAQPP-------------------------NLHLMNLQNMMAEQAPSRPPNLP-----------GQQGVQRGLSMS-MCHPGQMSLLGRTGVPPQQGMVPHGLHQ-------------------GVMSP---PQGLMTQQNFMLMKQR----GVGGEVYTQPPHMLSPQGSLMAPPPQQN-LMVSHPLRQRSVSLDSQMGYLPTPGGMANLPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q67FY2-1", "uniprot_id": "BCL9L_MOUSE", "id": "Q67FY2-1", "name": "B-cell CLL/lymphoma 9-like protein", "aln": "-----------------------------------------------MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQG----PTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAK-EVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDD-KPIAAAHNCNVADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGGGG--VPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAP---KVPPTPEPLP-LNTPSAGTPQSQPPPLPPPPP-APGSAP-PALPPEGPPEDTSQDLAPNSVGAASTGG-------GTGGTHPNTPTAATANNPLPPGGDPGS------APGSALLGEATPTGNGQRNLVG-SEGLSKEQLEHRERSLQTLRDIERLLLRSGE--TEPFLKGPPG---------------------GAGEGGPPAQAPSAAQPPPSAPPGG-LKKYEEPLQSMISQTQSLGGPPLEHEVPG-----HPQGGDMGQQMNMMMQ-RLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGG-----MMGRGPPPPYHSKPGDQ-WPPGMGAQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSMP---MEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPAMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPS-----QFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPGSVHLASNRGLGRRPSDLTISINQMGSPGMG---HLKSPTLSQVHSPLVTSPSAN-LKSP----QTPSQMVPLPSANPPGP-----LKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNP-------AAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQNSMMMAPGGPDSLNAPCGPVPSSSQ-MMSFPPRLQQPHGAMAPTGAGG--PGLQQHYPSGMALPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQ------PPKAQPP-------------------------NLHLMNLQNMMAEQTPSRPPNLP-----------GQQGVQRGLSMS-MCHPGQMSLLGRTGVPPQQGMVPHGLHQ-------------------GVMSP---PQGLMTQQNFMLMKQR----GVGGEVYTQPPHMLSPQGSLMGPPPQQN-LMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UU0-1", "uniprot_id": "BCL9L_HUMAN", "id": "Q86UU0-1", "name": "B-cell CLL/lymphoma 9-like protein", "aln": "-----------------------------------------------MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQG----PTCNVGSKGVGAGNHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRDRSVSVDSGEQREAGTPSLDSEAK-EVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDD-KPIGATHNCNVADPAMAAPQLGPGQTTQLPLSESSVPGAPHGPPPGLRPDAPGGGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAP---KVPPTPEPLP-LSTPSAGTPQSQPPPLPPPPPPAPGSAP-PALPPEGPPEDSSQDLAPNSVGAASTGG-------GTGGTHPNTPTATTANNPLPPGGDPSS------APGPALLGEAAAPGNGQRSLVG-SEGLSKEQLEHRERSLQTLRDIERLLLRSGE--TEPFLKGPPG---------------------GAGEGGPPAQAPPPPQQPPTAPPSG-LKKYEEPLQSMISQTQSLGGPPLEHEVPG-----HPPGGDMGQQMNMMIQ-RLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGG-----MMVRGPPPPYHSKPGDQ-WPPGMGAQLRGPMDVQDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQSMP---MEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPS-----QFPNQGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMG---HLKSPTLSQVHSPLVTSPSAN-LKSP----QTPSQMVPLPSANPPGP-----LKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNS-------AAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQ-MMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQ------PPKAQPP-------------------------NLHLMNLQNMMAEQTPSRPPNLP-----------GQQGVQRGLNMS-MCHPGQMSLLGRTGVPPQQGMVPHGLHQ-------------------GVMSP---PQGLMTQQNFMLMKQR----GVGGEVYSQPPHMLSPQGSLMGPPPQQN-LMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q67FY3-1", "uniprot_id": "BCL9L_DANRE", "id": "Q67FY3-1", "name": "B-cell CLL/lymphoma 9-like protein", "aln": "------------------------------------------------------------------------------------MHSENKLSNHGKQVTSGAQSQLPNVNQAQQQAPAGIQGSKGSVSGNHGVKANQISPGNPGLKSLNQTGGGGGMMKTKAKRERSVSIDTGDQRESLTPVLEPDAKVEGVMRSKRRCVLERKQPYSGDEWCSGAETEEEDEKPLSATH----REHVMCPSQGHSGSSTTGHVSDPGGPGLGSGHGPGIRTDLHS----------RPPQQVVYVFTTSLANSAAEAVMHGHTDSILLYHQQNVPRTKLDQSTGVGKVSNLAEHISSSHSPPIGTPKSQSGTPRPASVGGVGHLPGTSTPSSTGHPDSEPAQTHRGGGTSSNNGRSAVHTLGLGNSGPQSVGVSGTEGVDRPGAIPHHGAGVSPSTSPSVLSALRQSELGQRVGPGNTDGLSKEQLEHRERSLQTLRDIERLLLRSGTGVAQEDPRGPNGNPNGTNVNNNNSNDGGRGLEDGEIGGGIPGNCHINNAGMPGMPPVGGMKKYEEPLQSIISQTQNLGGPGLDDSLMGPHHGMPPHSHHLSSPSGLDMGPLLGPEGVTPEQLAWRKLQEEYYQEKRRQHDMNPHQHPQHFRIMPEMGMPGGPPMLMRGPPPPYHSKPGDQQWGP--GPMVGGGMGGNARMMDMNQEGPRGPRFLG-QMRGPSGGGGYPESPGGVLGVEGLGPQRPPRPGMGWLEEIPPNMGGGGPFHGCCP-PGGPGGPPQHFQGDLDRPMTREEIY--RRIHRLDLQQMSRQQQQAGLGGPRMMDNP--GGPGFPNPGMAGGPPSRGDPM--DFPVSRTIMGSPIG--GVGGDGGPTMRDIVDSPLGGNLNMNMGMNIN---QQQQLLAQKLRGGPGVLG-EMLNAEDISRIRASQNG--RGGANKAMIPGPEGPLQFPNQSS--FPGGQVDGPYLQQPG---PDMYGPDQPGPPHLSS-TSRLSHIPMNTGSR-------VTDLG-ARHPPDLPISVNPMGSPAIPPSHQLKSPSLSQEPSPLMPSPSAAGLKSPSQLPQSGPTHPPLPAASGAGTPSSTSIKSPQVMGPSLGLRSPSGSPGHLKSPSMPVASPGWTASPKAAMPSPGGP----PSVKVTGNGGSSSTDTGMSLP--PRSSNSTPISQP-SNSINPSMPFTSSPDAPPSQNPLSLIMSQMSKYAMPSSTPLYHDAIKTIATSDDEMLPDRPLQPGTNMSVG---GMGNHQSAQMLLSSQGAMGPHSGPQSPMGMVLQGGPPLSHDHPGPMLPSPNPMG--IPGMPSEIMGGG----------GGPPDGIGPCNVSPMHTQNQMGGFPRIQGP--LHSPIGGMG------QQFPP---RPDDVLP-------PQQMHLLSKGMSHQRPPHQPDSFPP--MPMGDGPDLSEVIRPTHRGIPEFDLSRIIPADKPSSTLQYFPKSETMSQPQQNPHQGQPPPQVSSAQLLKQLSSSGPPHSNIPSSNPHIANLQNMMAEQQLPLHPSHCGMRPGMGMPQIGSRGMGSGGGMGPMCHPGHM--MGRTGMSPQQQLQQQHHHQQQQAMMANNLLQHPSHPPRGMLSPQQHPHNLIAQQNLMMMQAKQRGMALPGEHFGQQGALMSPQGPMMGPPHSQTGMMGPQSLRQRSMSLDSPLGYG--PGSMANMPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.****:**** ..***** ****. *: **** :*.**.*******.*..**. : . :* *.**:****:*:*:***: ** *:.:** * . **********************.::**:* **:.*:* : .* ..* .*.:: :*: . ** * **:*.* . :**.*.****** ***:*****::*:::*** ********:****:. **. .* :. :*. ***:**. . *.. . * * .: * . *:. : .. *::*..* * *.: *:: .: ::. **. * :...::*. . *** * ::**************************** :: :** * * ** *.:. * ** * :*********:*****.**** *:..: * * . .:.. .: : ** :.:****:**********:****:.: : : :: * ** *: ************** * * *. : * *. : * **** * *:: .* ** . * : * . *** ****.* *::** * .. :. * *** * . :.: : . : *.:: * : *: . .: **:: .* : *:** * ** :* .* ::..*:* *: . * . :: :. *:****.:*:: *** *::**:** .::* : *..*:::*:**.:.. .*.:* ::*. *****.. *.*** : * **:.***.. * *:****:*: ..*. ..: * .*:*.**.**:* ****.: :****:*** ***:.**** **** *: . ***:*. .*. :*****:..**.:***:***.:******.*.****.****:****** . *.:.:... .. : * * **.*.*:* ::* *. :***:*******..********:*:***************:***********:****** * . . * *:.* *. ** :.. :..****** * * ****: * .*****.*:* ** *. ** *** . **. * :* * **:* * :. *. * *::*. * : ** * * **:.*.*: : * .. * .: :.*:******** ************::***********.*. * :.*** * *: ********* . *. *.:*: * .*. *****:* :****:.*** : : ** *::** *:.*::***:*:*: : .: ** : * ::****.:*.** .*. :* .:.*****:**** :** **.***:**", "identical_positions": 651, "similar_positions": 375, "identity": "38.16%" }, { "cls_id": "homologset.agr.MGI:1933117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CAS9-1", "uniprot_id": "PARP9_MOUSE", "id": "Q8CAS9-1", "name": "Protein mono-ADP-ribosyltransferase PARP9", "aln": "-MAYYMDTWAAAPAERPG-----MIASLSLSFKK---------------------------AFAELFPQR--------RRGHSEGDYPP-------------LRG----------SANNSLEEHYRWQIPIKHNVFEILKSNESQLCEVLQNKFGCISTLSCPTLAGSSSPAQRVFRRTLIPGIELSVWKDDLTRHVVDAVVNAANENLLHGSGLAGSLVKTGGFEIQEESKRIIANVGKISVGGIAITGAGRLPCHLIIHAVGPRWTVTNSQTAIELLKFAIRNILDYVTKYDLRIKTVAIPALSSGIFQFPLDLCTSIILETIRLYFQDKQMFGNLREIHLVSNEDPTVASFKSASESILGRDLSSWGGPETDPASTMTLRIGRGLTLQIVQGCIEMQTTDVIVNSGYMQDFKSGRVAQSILRQAGVEMEKEL--DKVNLSTDYQEVWVTKGFKLSCQYVFHVAWHSQINKYQILKDAMKSCLEKCLKPDINSISFPALGTGLMDLKKSTAAQIMFEEVFAFAKEHKEKTLTVKIVIFPVDVETYKIFYAEMTKRSNELNLSGNSGALALQWSSGEQRRGGLEAGSPAINLMGVKVGEMCEAQEWIERLLVSLDHHIIENNHILYLGKKEHDVLSELQTSTRVSISETVSPRTATLEIKGPQADLIDAVMRIECMLCDVQEEVAGKREKNLW-SLSGQGTNQQEKLDKMEESYTFQRYPASLTQELQDRKKQFEKCGLWVVQVEQIDNKVLLAAFQEKKKMMEERTPKGSGSQRLFQQVPHQFCNTVCRVGFHRMYSTSYNPVYGAGIYFTKSLKNLADKVKKTSSTDKLIYVFEAEVLTGSFCQGNSSNIIPPPLSPGALDVNDSVVDNVSSPETIVVFNGMQAMPLYLWTCTQDRTFSQHPMWSQGYSSGPGMVSSLQSWEWVLNGSSV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AD67-1", "uniprot_id": "A0A8I6AD67_RAT", "id": "A0A8I6AD67-1", "name": "", "aln": "MCARGMDSGSLTSSGDGGSGLEAMAGCVWLAWGSGVLHNQDREKARPAPETREAKFQFRFPGGPSLFPAEPPPLLLCSRPGPSPGHHLLDYRVHLETQTSINIRRPAWDVKNGLLHADDSLEHYHRWQIPIKHNIFEILKSNESQLYEVLQKKFGCICTLRYPTPAGSSSPAQKVFRRMLTPGIELSVWKDDLTRHVVDAVVNAANEDLLHGGGLAGSLVKIGGSEIQEESKKWIATHGKIPVGGFAVTRAGKLPCYLIIHAVGPRWTVMDSQTAIGLLSVAITNILDYVTKWNTCIKTVAIPALSSGIFQFPLHLCTRIIVETICLYFQDKQTVSNLREIHLVSNEGPTVESFKSSSENIFGKEPSSWESLETNPSSNVTLHIGQGLTLQIVQGCIELQTTDVIVNSGHLQDFKSGQVAQSILKRAGFEMEMEL--DKIKLSSDYQVVQVTKGFKLSCQYVFHVSWHYSISKDQILKNAMKSCLERCLKRDINSISFPALGTGAINLEKSIAAKIMFEEIVAFAKEHKEKTLTVKIVIFPVDVETYKVFCAEMTKRSSELNLNSDGGLLSLPWTRGEQRSSSLEDGSPAIDLMGVEVGEMCEAKEWIERLLTSKDHHIVENNHILYLGIKEHGMLSQLQTSSNVSISATVSPRTATLEVKGSQADLIEAVMKIECMLCGVQEEVAGKKERSLR-SLSGWGTDQQGKLKEMEESCTFQRYPVSLTQEFLDQKKHFDKCGLCVVKVEEVDNEVLLAAFQEKKKMMEEKMPKGSGSQRLFQQVPHQFCNAVCRVGFHRLYSTHNDPVYGAGIYFTKSLKKLADKARKTSSTDRLIYVFEAEVLTGSFCQGNFSNIIPPPLSPGALDVHDSVVDSVSNPETFVIFSGVQAMPRYLWTCTQDRTFSQHPMWSQGYSSEPGMASSLQSWGRVSNGSPV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IXQ6-1", "uniprot_id": "PARP9_HUMAN", "id": "Q8IXQ6-1", "name": "Protein mono-ADP-ribosyltransferase PARP9", "aln": "-MDFSMVAGAAAYNEKSG-----RITSLSLLFQK---------------------------VFAQIFPQW--------RKGNTEECLPYK------------------------CSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSK-SLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGK---SELGQETTPSFNAMVVN--NLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYS---VPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQEYVQSQD------YSSGPMRPFAQHPWRGFASGSPVD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : * .: * : . ..:** * * : .:* . : *****:** *:***.** ** ****:*****.** *. *.*. : :***: * * *********** *.**********:****.*** :*** ** *******: :* **:..* :*:* **:*** ********* :.* . *. ** .**:** : ******************.*** *:*** : :*.* ..**:********.*** :**::** *:*: * . ** *: . : .******** ** **:****** :*:. * **:***::**.**: *: * : * * *****:* *:*::** ** .: * ****.***.***:*:: :*.********** ::::*. **:*:*:*:.:***:* :: ****:****.*:* ** * :**:***. *.*.. . : *:* ..** ****:***.:* ** **: **:*:* :***:********* ***.:**:**.:: ***: :** : **::*.:****:.**.** *** ****:* *:*:.* **. :** . .:*:*. * : *.. ***: *:**:*:**** *::**::**:**:****.*******: : . *:*******:****.******:*:*** :* *********.**:**:*.:* *::*:************ ****: **:********:* :*****.**.***:*:*.*:**:* *******: . **. *** * : :.* . .**.* ", "identical_positions": 462, "similar_positions": 202, "identity": "49.46%" }, { "cls_id": "homologset.agr.MGI:1933118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16290-1", "uniprot_id": "PGAM2_RAT", "id": "P16290-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MATHRLVMVRHGESSWNQENRFCGWFDAELSEKGAEEAKRGATAIKD-----AKIEFDICYTSVLKRAIRTLWTILDVT--------------------------DQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYASISKDRRYAG-LKPEE----------------LPTCESLKDTIARALPFWNEEIAPKIKAG--KRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNQELKPTKPMRFLGDEETVRKAMEAVAAQGKAK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70250-1", "uniprot_id": "PGAM2_MOUSE", "id": "O70250-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MTTHRLVMVRHGESLWNQENRFCGWFDAELSEKGAEEAKRGATAIKD-----AKIEFDICYTSVLKRAIRTLWTILDVT--------------------------DQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYTSISKDRRYAG-LKPEE----------------LPTCESLKDTIARALPFWNEEIAPKIKAG--QRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELDQNLKPTKPMRFLGDEETVRKAMEAVAAQGKAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15259-1", "uniprot_id": "PGAM2_HUMAN", "id": "P15259-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKD-----AKMEFDICYTSVLKRAIRTLWAILDGT--------------------------DQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRYAG-LKPGE----------------LPTCESLKDTIARALPFWNEEIVPQIKAG--KRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGB6-1", "uniprot_id": "Q9VGB6_DROME", "id": "Q9VGB6-1", "name": "Phosphoglycerate mutase", "aln": "MLALARNSWCGQLLCRVANIEARCPFSKSSSGGKQAEKKGKYRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKD-----AKIEFDVAHTSVLTRAQETLRAALKSS--------------------------EHKKIPVCTTWRLNERHYGGLTGLNKAETAKKFGEEKVKIWRRSFDTPPPPMEKDHEYYACIVEDPRYKDQLKPEE----------------FPKSESLKLTIERTLPYWNEVIVPQIKDG--MRVLIAAHGNSLRGVVKHLECISDKDIMSLNLPTGIPFVYELDESLKPLATLKFLGDPETVKKAMESVANQGKAK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAN7-1", "uniprot_id": "Q9VAN7_DROME", "id": "Q9VAN7-1", "name": "Phosphoglycerate mutase", "aln": "-------------------------------------MGGKYKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKD-----AGLEFDVAHTSVLTRAQVTLASILKAS--------------------------GHKEIPIQKTWRLNERHYGGLTGLNKAETAAKYGEAQVQIWRRSFDTPPPPMEPGHPYYENIVKDPRYAEGPKPEE----------------FPQFESLKLTIERTLPYWNDVIIPQMKEG--KRILIAAHGNSLRGIVKHLDNLSEDAIMALNLPTGIPFVYELDENFKPVVSMQFLGDEETVKKAIEAVAAQGKAK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00950-1", "uniprot_id": "PMG1_YEAST", "id": "P00950-1", "name": "Phosphoglycerate mutase 1", "aln": "----------------------------------------MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKE-----KKVYPDVLYTSKLSRAIQTANIALEKA--------------------------DRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQ--KGDERYKY-VDPNV----------------LPETESLALVIDRLLPYWQDVIAKDLLSG--KTVMIAAHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDENLKPSKPSYYL-DPEAAAAGAAAVANQGKK---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12008-1", "uniprot_id": "PMG2_YEAST", "id": "Q12008-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------MTASTPSNVMTLFLLRHGQSELNHENIFCGWIDAKLTEKGKEQARHSAELIEQYCKANNLRLPQIGYTSRLIRTQQTIETMCEEFKLKPQLQVVYDFNKIKLGDEFGSDDKDNMKIPILQTWRLNERHYGSWQGQRKPNVLKEYGKDKYMFIRRDYEGKPPPVDLDREMIQQENEKGSSTGYEFKEPNRQIKYELECSNHDIVLPDSESLREVVYRLNPFLQNVILKLANQYDESSCLIVGHGSSVRSLLKILEGISDDDIKNVDIPNGIPLVVELDKNNGLKFIRKFYLDPESAKINAEKVRNEGFIKNP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::***:* *.:* * ** *.:*: ** ::* .. ::: :: :** * *: * . . :*: :*********. * *.:. :.*: : **.:: ***:: . :* *** .: * *: :: * :*..**.*:*.::* *: :*: * :::*.***:* **::. : * *:. * :* ", "identical_positions": 64, "similar_positions": 69, "identity": "18.66%" }, { "cls_id": "homologset.agr.MGI:1933124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K734-1", "uniprot_id": "A0A0G2K734_RAT", "id": "A0A0G2K734-1", "name": "SH3 domain-binding protein 5", "aln": "MADLKKSPGGRETPQGELRPEVVEDEVPRSPVEEEPGGGGSNSSETKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMAD--KNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRG--LPPHP----LGPRRSSPVG--------------------------------AEAGPEGIEDGDSGIEGAEGGGLEEGSSLGPGPGPDTDTLSLLSLRTVAS-DLQK------------CDSVEHLRGLSDHAS------LDGQE-----LGAQSRGRRGSDGGVRGGRHQRSVSL--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LH9-1", "uniprot_id": "3BP5L_MOUSE", "id": "Q99LH9-1", "name": "SH3 domain-binding protein 5-like", "aln": "MADLKKAAGGRETPQGELRSEVVEDEGPRSPVAEEPGGSGSNSSETKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMAD--KNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRG--LPPHP----LGPRRSSPVG--------------------------------AEAGPEGIEDGDSGIEGAEGGGLEEGSSLGPGPGPDTDTLSLLSLRTVAS-DLQK------------CDSVEHLRGLSDHAS------LDGQE-----LGAQSRGRRGSDIGVRGGRHQRSVSL--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L8J4-1", "uniprot_id": "3BP5L_HUMAN", "id": "Q7L8J4-1", "name": "SH3 domain-binding protein 5-like", "aln": "MAELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMAD--KNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGG-LPPHP----LGPRRSSPVG--------------------------------AEAGPEDMEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLSLRTVAS-DLQK------------CDSVEHLRGLSDHVS------LDGQE-----LGTRSGGRRGSDGGARGGRHQRSVSL--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V785-1", "uniprot_id": "3BP5H_DROME", "id": "Q9V785-1", "name": "SH3 domain-binding protein 5 homolog", "aln": "-----------------------------------------------MSSAEDGELDPQIQIELENLNSATDEINKLEIELEEANSTFRILLNESTRRLKVSSKKLGNCIEKARPYYEALDKAREAQIECQKAAVKFQRANEIHAAAKETVALAEQRFMSNSHEWQFDNAWQEMLNHATQKVMDAETQKADCHAEHQRLTKLFNAAEQKLQQLEDRFRRSINKSRPYFEEKQVCQDQLQTQKNRIQELQQQVAGAKSTYSTALRNLERISEDIHRQRGDFPTPPGPREPGVGAELNSPTSSALPSLPDFQLELEKCDYPSIAGSQMSLGAKTPQAAAETEDEEDACDYDETGAGELRGVVDERDLEALRQKVKILAVRPIEGGDGQQQNDVWEHELKATVDKLDHLMMLKETAKRQQTNRLKSTEQRPDSLGAEALKRHCDVVEVKVTSCATTASLPVTPHHQLNHLAPPTPIKKLQQQLAPLPSVNVSMRELPLLARLSNELLDRSSAAFGGVRKTLRRRSLE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *: ****:** ***:**.*::***::*::*:**.:*:* :*:**:*:*:....:**.*********** *:*** * ****::::** .:* **:* * :*** .*:: : ::* :********* ** :** :: . ****:*:* : ** ::* *:. :**:*.******* * .: *: :* :: **:**** **: **.******:***:** :* . ** * :*.. .**.. .:*..* :: *: . *.* .* . . :.:.:*::*.: . * *: *.::** *.: .. *.. * **:.: *: . .: :.** ", "identical_positions": 147, "similar_positions": 117, "identity": "28.05%" }, { "cls_id": "homologset.agr.MGI:1933126", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLH7-1", "uniprot_id": "CK5P3_RAT", "id": "Q9JLH7-1", "name": "CDK5 regulatory subunit-associated protein 3", "aln": "MQDHQHVPIDIQTSKLLDWLVDRRHCNLKWQSLVLTIREKINTAIQDMPESQEIAQLLSGSYIHYFHCLRIVDLLKGTEASTKNIFGRYSSQRMKDWQEIISLYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQDYSRKEEEGQAGAAEMREQFYHSCKQYGITGDNVRRELLALVKDLPSQLAEIGAGAQS-LGEAIDLYQACVEFVCDSPTEQVLPMLRYVQPKGNSTVYEWRTGTEPSVVERP----QLEDPPEQVQEDEIDWGDFGLEAVSDSGNI-ISAETPGIDWGISLESESKDAGADKIDWGDN-AVASEITV-----------LETGTEAPEGVARGSDALTLLEYPETRNQFIDELMELEIFLSQRAVEMSEEADILSVSQFQLAPAILQGQTKEKMLSLVSTLQHLIGQLTSLDLQHLFMILASPRYVDRVTELLQQKLKQSQLLALKKDLMVEKQQEALQEQAALEPKLDLLLEKTRELQKLIEADISKRYNGRPVNLMGTSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LM2-1", "uniprot_id": "CK5P3_MOUSE", "id": "Q99LM2-1", "name": "CDK5 regulatory subunit-associated protein 3", "aln": "MQDHQHVPIDIQTSKLLDWLVDRRHCNLKWQSLVLTIREKINTAIQDMPESQEIAQLLSGSYIHYFHCLRIVDLLKGTEASTKNIFGRYSSQRMKDWQEIVSLYEKDNTYLVELCSLLVRNVSYEIPSLKKQIAKCQQLQQEYSRKEEEGQAGAAEMREQFYHSCKQYGITGDNVRRELLALVKDLPSQLAEIGAGAQS-LGEAIDLYQACVEFVCDSPTEQVLPMLRYVQKKGNSTVYEWRTGTEPSVVERP----QLEEPPEQVQEDEIDWGDFGVEAVSDSG---IVAETPGIDWGISLESEAKDAGADKIDWGDDAAAASEITV-----------LETGTEAPEGVARGSDALTLLEYPETRNQFIDELMELEIFLSQRAVEMSEEADILSVSQFQLAPAILQGQTKEKMLSLVSTLQQLIGRLTSLRMQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVEKQQEALQEQAALEPKLDLLLEKTRELQKLIEADISKRYSGRPVNLMGTSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JB5-1", "uniprot_id": "CK5P3_HUMAN", "id": "Q96JB5-1", "name": "CDK5 regulatory subunit-associated protein 3", "aln": "MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVLTIREKINAAIQDMPESEEIAQLLSGSYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERP----HLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDD-AVALQITV-----------LEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPVNLMGTSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95SK3-1", "uniprot_id": "CK5P3_DROME", "id": "Q95SK3-1", "name": "CDK5RAP3 protein homolog", "aln": "-MNESEIPIDIHTLKLQDWLISRRIVPKNVQQELREIHRKISNALQDMPSNEQLIKLLARTNINYYHVKEIIEILKQTEKDTKSVFGTYGSQRMKDWQEISRLYEKNATYLAETAQIFVRNVNYEIPGVRKQMARLEQQADETQKRAHDLNKPESQILADHSALLEQLGVKGDNLHAEFVQVLSGLPELYDKSLVGIAN-IQPGIDLYAEVSG------NKQVLPILNHLVEFGNTTVYQYIHKEAPLAVEEPPIRLNLSEGNASKDDNAVAEIDFGTDDNGGTS---STVSAEIIDYGDFGSGDLPESDGGNIDWGIESAPTDAVEINFDIPVEEYGIVVEGTGMDGGTAKGDQAYTLLDSPNYRDRFLDEIYELESFLRMRIYEL-KQLESSSDIMFSLMDNIAT-HDGESIWKILVSVEKIIQQTSDKQTQHLFQLKHSPKYANMLATKLQQMTKAVEKLRATREALKQLTIELREQRQDLNPVLEELIAQTRTLQSHIEKDISKRYKNRVVNLMGGVN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...:****:* ** ***:.** : *. : *:.**. *:****..::: :**: : *:*:* .*:::** ** .**.:** *.********** ****: ***.* ..::****.****.::**:*: :* :: .:: .: : ::: :. :* *:.*:*:: *:: ::..**. : .. . : .**:* .:****:*..: **:***:: * .**.* :*.: . :: : *** : . ..: **:* ..: :.... **** : * : : : : ** *.*:* :* ***: .: *::*:**: *** ** * *: :: : * *.* * : *.: .:: ::.:* : :. **** : **:*.: :: *** * : * .:: : : * ::: *:* *: *: :*: **. ** ******..* ***** ", "identical_positions": 162, "similar_positions": 167, "identity": "31.03%" }, { "cls_id": "homologset.agr.MGI:1933131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MG9-1", "uniprot_id": "KCIP4_RAT", "id": "Q99MG9-1", "name": "Kv channel-interacting protein 4", "aln": "---------------------------------------------------------------------------------------------------------MNVRRVESIS----------------------------------------------------------------------------AQLEEASSTGGFLYAQNNTKRSIKER----LMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDS-TTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PHZ8-1", "uniprot_id": "KCIP4_MOUSE", "id": "Q6PHZ8-1", "name": "Kv channel-interacting protein 4", "aln": "---------------------------------------------------------------------------------------------------------MNVRRVESIS----------------------------------------------------------------------------AQLEEASSTGGFLYAQNNTKRSIKER----LMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDS-TTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIL6-1", "uniprot_id": "KCIP4_HUMAN", "id": "Q6PIL6-1", "name": "Kv channel-interacting protein 4", "aln": "---------------------------------------------------------------------------------------------------------MNVRRVESIS----------------------------------------------------------------------------AQLEEASSTGGFLYAQNSTKRSIKER----LMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDS-TTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7H4-1", "uniprot_id": "E7F7H4_DANRE", "id": "E7F7H4-1", "name": "Kv channel-interacting protein 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRRRRCKRQ----LIKFTQHIARLITGTLNTDNEDEEQESTTERYHPENLEQLQSQTHFSRQELQLLYRGFKNDCPSGVVNEDTFKNIYALFFPLGDS-SKYAQFLFNAFDKDKNGSLSFEELVCDLSVLLRGTTEEKLNWAFNLYDINKDGQITKEEMLDIMKSIYDLMGKSIHPRLKEEAVRQHVRMFFQNMDINQDGVVTIDEFIDSCEKDEHIMQSLKIFDNAV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IR92-1", "uniprot_id": "Q8IR92_DROME", "id": "Q8IR92-1", "name": "EF-hand domain-containing protein", "aln": "MAGPQVQHSQRPNSAYYTGLNGGSGSGGGGGGGGAGGGGAGGGSSAGMSSSASHTGLHALRQVSNETELIYRGSHSNGTVNELPSSAQHHLLTGRAVQQHQQQQQMHHQTVSSIAGTGSSVTDALISTINSGGGGGGPSGSSCSTAALGIKKSSTQRSIEIIVDASQCGKELVASGPGSGAAGSGAAIVSTLDVEDVEQGGGGQESSSSHRKSSRHRHRPLHRRLITYLRNLFQGSTTQNDSELEEFETPARYRPDSLSALSRATRFTEDEIKRIYRGFKAECPTGVVKEDTFKVIYSQFFPQGANPTLYAHYVFNTLDQDHSGIVSFEDFVQGLSILSRGSVEEKLRWTFSLYDINGDGFITREEMTDIVTAIYELMGRLPDECPEEEKIKGKVEQIFQKMDTNRDGVVTLEEFLEACRNDDAISRSMSYTVPRRRRHQLSAQQQHLQHQKHQQQEPEKRKSNHKTKNKQQQKQQQPHSTRHQNCCHIIDMDGDSTTSTTTASAATGTTLNCNVLYDYGAAEEDDDDQDEDDEDSDEEYRSFVCRHCQRSQSVVQQPRSNRRSQSQSKSRKRSKSRKRHQSKQGHHQGQQGHQGHHGQQLTRWPEINVANEQAIRFRCPQVGPQVGRDLHTPQPMHFHHPQSQSQKAKSKSRPRKHRACPPASLSKAGAAAAAAAPGPPAPPAPPADPSQLPPSEQHPLAPLNVIVGGAEVEVDPQQPQPPTTPDSPSLVTVSTWYTVAKQGVSC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBL2-1", "uniprot_id": "Q9VBL2_DROME", "id": "Q9VBL2-1", "name": "EF-hand domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASPPESPIEEVVYELEHTRVP-KPIPVALEDLCRQTKFTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKFFPHGNS-SLYAHYVFKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILAIHELMGRRPHQPEDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQMFDNDLXX---------------------------------QEGELEPGLRNSRTIISLIDL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : * .. : * *. * ::*:..*:: :***** :** ***:*: ** **: *** * . : **:::*:::* : .* :**.::: ** * **:. *:*.*:*.***:* ** *:: *: :*: :*:::**: .: : :* .*:::* *:**::*::**:::* :*: : :*:. ", "identical_positions": 65, "similar_positions": 73, "identity": "8.71%" }, { "cls_id": "homologset.agr.MGI:1933134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTV1-1", "uniprot_id": "TUSC3_MOUSE", "id": "Q8BTV1-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "aln": "MSARAAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFVKAPP--RNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWR------YSSAFCNKLFFGMVDYDEG----TDVFQQLNMNSAPTFMHFPSKGRPKRA----DTFDLQRIGFAAEQLAKWIADR---TDVHIRVFRPPNYS-GTIALALLVSLVGGLLYLRRNNLEF--IYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE---------AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFLIK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAE2-1", "uniprot_id": "A0A0G2KAE2_RAT", "id": "A0A0G2KAE2-1", "name": "", "aln": "MSARAAPSRRRQAGRRLRYLSTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFVKAPP--RNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWR------YSSAFCNKLFFGMVDYDEG----TDVFQQLNMNSAPTFMHFPSKGRPKRA----DTFDLQRIGFAAEQLAKWIADR---TDVHIRVFRPPNYS-GTIALALLVSLVGGLLYLRRNNLEF--IYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE---------AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDLDIE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13454-1", "uniprot_id": "TUSC3_HUMAN", "id": "Q13454-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "aln": "MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFIKAPP--RNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWR------YSSAFCNKLFFSMVDYDEG----TDVFQQLNMNSAPTFMHFPPKGRPKRA----DTFDLQRIGFAAEQLAKWIADR---TDVHIRVFRPPNYS-GTIALALLVSLVGGLLYLRRNNLEF--IYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE---------AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDLDFE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48439-1", "uniprot_id": "OST3_YEAST", "id": "P48439-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3", "aln": "----------------------MNWLFLVSLVFFC---GVSTHPALAMSSNRLLKLANKSPKK-IIPLKDSSFENILAPPH--ENAYIVALFTATAPEIGCSLCLELESEYDTIVASWFDDHPDAKSSNSDTSIFFTKVNLEDPSKTIPKAFQFFQLNNVPRLFIFKPNSPSILD----HSVISISTDTGSERMKQIIQAIKQFSQVNDFSLHLPMDW-TPIITSTIITFITVLLFKKQSKLMFSIISSRIIWATLSTFFIICMISAYMFNQIRNTQLAGVGPKGEVMYFLPNEFQHQFAIETQVMVLIYGTLAALVVVLVKGIQFLRSHLYPETKKAYFIDAILASFCALFIYVFFAALTTVFTIKSPAYPFPLLRLSAPFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03723-1", "uniprot_id": "OST6_YEAST", "id": "Q03723-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6", "aln": "----------------------MKWCSTYIIIWLAIIFHKFQKSTATASHN-IDDILQLKDDTGVITVTADNYPLLSRGVPGYFNILYITMRGTNSNGMSCQLCHDFEKTYHAVADVIR------SQAPQSLNLFFTVDVNEVP-----QLVKDLKLQNVPHLVVYPPAESNKQSQFEWKTSPFYQYSLVPENAENTLQFGDFLAKILNISITVPQAFNVQEFVYYFVACMVVFIFIKKVILPKVTNKWKLFSMILSLGILLPSITGYKFVEMNAIPFIARDAKNRIMYFSGGS-GWQFGIEIFSVSLMYIVMSALSVLLIY--------VPKISCVSEKMRGLLSSFLACVLFYFFSYFISCYLIKNPGYPIVF--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: :. : : : .: : . :: :. ..: : * :.: : *.:* : :. *. :. .: .:** : . .: ::::..* :. : . .: . .*. : : :.: : * ::: : ::: :: * : :* ::: :. : .:. ..:. : : .. ** * : :: .:: *:* : ::. . .: **: : : : * .** ", "identical_positions": 21, "similar_positions": 109, "identity": "5.48%" }, { "cls_id": "homologset.agr.MGI:1933137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8X8-1", "uniprot_id": "D4A8X8_RAT", "id": "D4A8X8-1", "name": "", "aln": "-------------------------------------------------------------------------MNLEKLSKPELLTLFSILEGELEARDLVIEAL-------------------KAQHRDTFIEERYGKYNISDPLMALQRDFETLK---------EKNDSEKQPVC-----TNPLSILKAVMKQCKNMQERMLSQLAAAESRHRKVILDLEEERQRHAQDTAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERSRHKQLSSMLVLECKKATSKAAEEGQKAGELSLKLEKEKSRASKLEEELAAERKRGLQTEAQVEKQLSEFDIEREQLRAKLNREENRTRALKEEMESLKKLVKDLEAAQQHSNSSEQGREPVTTSRGTATEPPMRVSVFCQTESIQTERSHSSIMTKLTDTGLPGPSSAPYPYAKANGHCDPETQTTRELTSDSSTENQGPPREKSAVPAQEKPMENGGCPVGTEIPVTMPSHLPSSGSSLSPSSTASSSLTSSPCSSPVLTKRLLGSSVSSPGYQSSYQVGVNQRFHAARHRFQSQADQDQQASGLQSPPSRDLSPTLL-----DNSAAKQLARNTVTQVLSRFTNQ-GPIKPVSPNSSPFGTDYRNLVSTANPRGDTSHSPTPGKVSSPLSPLSPGIKSPTIPRAERGNPPPIPPKKPGLTPSQSVATPGTKTHSQASSLTTTEDLASSCSPSAVVANGKDVEMLVPTSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LJ0-1", "uniprot_id": "CT2NL_MOUSE", "id": "Q99LJ0-1", "name": "CTTNBP2 N-terminal-like protein", "aln": "-------------------------------------------------------------------------MNLEKLSKPELLTLFSILEGELEARDLVIEAL-------------------KAQHRDTFIEERYGKYNISDPLMALQRDFETLK---------EKNDSEKQPVC-----TNPLSVLKAVMKQCKNMQERMLSQLAAAESRHRKVILDLEEERQRHAQDTAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERTRHKQLSSMLVLECRKATSKAAEEGQKAGELSLKLDKEKSRASKLEEELAAERKRGLQTEAQVEKQLSEFDIEREQLRAKLNREENRTRALKEEVESLKKLVKDLEAAQQHRSTSEQGREPVTMSRGTATEPPMRVSAFCQTESVQTERSHGSVITKLTDTGLPGPTTAAYSYAKANGHCDPEIQTTRELTSDSSTENQGPPREKSAVAAQEKPVENGGCPVGTETPVTMPSHLPSSGSSLSPSSTASSSLTSSPCSSPVLTKRLLGSAASSPGYQSSYQVGINQRFHAARHKFQSQADQDQQASGLQSPPSRDLSPTLL-----DNSAAKQLARNTVTQVLSRFTNQ-GPIKPVSPNSSPFGTDYRNLASTASPRGDTSHSPTPGKVSSPLSPLSPGIKSPTIPRAERGNPPPIPPKKPGLTPSQSATTPVTKTHSQASSLAATEDLASSCSPSAVVANGKDVEILLPTSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2B4-1", "uniprot_id": "CT2NL_HUMAN", "id": "Q9P2B4-1", "name": "CTTNBP2 N-terminal-like protein", "aln": "-------------------------------------------------------------------------MNLEKLSKPELLTLFSILEGELEARDLVIEAL-------------------KAQHRDTFIEERYGKYNISDPLMALQRDFETLK---------EKNDGEKQPVC-----TNPLSILKVVMKQCKNMQERMLSQLAAAESRHRKVILDLEEERQRHAQDTAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERSRHKQLSSMLVLECKKATNKAAEEGQKAGELSLKLEKEKSRVSKLEEELAAERKRGLQTEAQVEKQLSEFDIEREQLRAKLNREENRTKTLKEEMESLKKIVKDLEASHQHSSPNEQLKKPVTVSKGTATEPLMLMSVFCQTESFPAERTHGSNIAKMTNTGLPGPATPAYSYAKTNGHCDPEIQTTRELTAGNNVENQVPPREKSVALAQEKPVENGGCPVGIETPVPMPSPLSSSGSSLSPSSTASSSLTSSPCSSPVLTKRLLGSSASSPGYQSSYQVGINQRFHAARHKFQSQADQDQQASGLQSPPSRDLSPTLI-----DNSAAKQLARNTVTQVLSRFTSQQGPIKPVSPNSSPFGTDYRNLANTANPRGDTSHSPTPGKVSSPLSPLSPGIKSPTIPRAERGNPPPIPPKKPGLTPSPSATTPLTKTHSQAASLTTAEDLASSCSSNTVVANGKDVELLLPTSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E9R1-1", "uniprot_id": "A0AB40E9R1_DANRE", "id": "A0AB40E9R1-1", "name": "", "aln": "--------------------------------------------------------------------MKGSRMNVETLSKAELLMLLSILEGELEAQDVVIHTLRVHSPRTLWPVFTEWYRTVQAQQRNTFVQERYGQYDLSDPFVALLRDSELSQ---------AQDDGRQSPVC-----LNPLGVLKLVMAHCTNMKEKLLKQLAAAERRHRRVIADLEEEKRRRAQDAAAGDDITDMLERERDRLLQQLESERAQLERLERERSVLSSQAVEDLAEQQQLSSTLAKECQKATARAEEESQRVAELSRQLEQESRAMESLKGELESERTRAQQIEARTERKLAEFDTEREQMRGKLLKEEKRYQELLEQFNSLKKELDEMKEREKAGLDNEEKLKIPHKATSGITPPVSQVEADGKIATPKASPQH-----------------------KQNGHHTPR-------------EPEFPAEER---CKEEGLADNG---------VVLPGGS-GGFQCLSPSSPASSSLSSSPCSSPVLTKRLASLGCSSPTYPSSYQASINQRFQAARHKFQQQAEAEQQHGGTVVHSPRDLSPTACTPPPPDNSTAKQIARNTVTQVLSRFTNPVSSKLPQS-NSSPFGTDYRNLAAASSPTGKS-----PG-------ILSPGIRSPIIPRAEKFHSPPVPAKKQGVNQSPNSPVPS----SRASHFP---ELTGSCGLTSSQEDAKELDLVVSSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q9J8-1", "uniprot_id": "F1Q9J8_DANRE", "id": "F1Q9J8-1", "name": "", "aln": "-----------------------------------------------------------------MAPTTEPRLNVEALSKRDVLLLFSVLEGELEARDFVIQAL-------------------KAQHKDSYVCERYGKYNLSDPFLALQRDSETLQSSSQTREDRASSSQRRDGVCGAKARSDPLAVLKLVVGHCRRMQEKMLKQLAAAENRHRRVIADLEEEKRKHAEDTAEGDDVTYILEKERERLLQQLEFEKSKTSRMERENKRLHDQLNEQQVQQKQLMTALSRECKRSGTRAYEESQRAAELSQRLERERAANQTLRAELEEEKKRAMQMEARREELLAEFDTEREQLGLRLRKEEARCNALQEELETLGKETTDSVNGHHISMVEDAEK---------------------------------------------------------------------------------------------------------------------------PS---------------LLSNGTTSQASQSPDIQAAYQAGIHQRFHAARHKFQGTSDQDPNPVSSTINCPHDISPCPTSP---DIISSKQAPRG---TMLSRFSTPQSPSKSTSSNSSPFGTDYRAVVQSG--------------------MLSPTIRSPTIPRADRGIPPPIPPKKPGLAETPPSPATL-----RAAHFA---HMTVGCGRNSSSENSKEPDLMLSSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SX68-1", "uniprot_id": "CT2NL_DROME", "id": "Q8SX68-1", "name": "CTTNBP2 N-terminal-like protein", "aln": "MEQNSNSSVADTFAEAPATDADYGTENCSGSGMSVGDTVSANHEFQTMKPGPGVVHKVMPVANSASSATATNGRTRSEMPHSELVKMLYYLEGELQARDVCIAALR------------------NERVKQLIAQLRTKRLQPNDPYAAIFRDKIALNGNLISRESSTQAAQAEMEVR--QIIEQQMEQQYQMVSKQRATHVRMVNILTESLENNQRMLQELEEEKRKHENTTAQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKKLQETLEYERNRQKQIVLLLIAERKKILMKYIEEGKRSEDLAQILAEEKQRSDTIAEGLEEESKKSLRMEEELEKQTHAMEQERKVLFAKLAKEELRVKELEQELNALRSEHEALKKQQQLGGSGSSVAAAKARQFSDDACATPPMVNIAKIVQP-----------------------------------------------------------------------------------------------TATVSSMPVSGPQTGIARSIAPGQNIRSAGIATAPTGTATAAIAPLTAVLNHTTTITTTTNNTTTSSNSNSSGSIGVAATAA---AVAASVETAATVTVPMVAPPSPSPAKMQPTATIQRAPGGKYAALAAAAALDQTTTPHPHPVP------IAVPPVTVP--PAGARGAPPPIPTKP--IVPPKREPSLS-----RLGSITGSSAIAAATAATTAAGTAKQN--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :.: ::: :: *****:*:*. * :* : : :: * : : .** *: ** : . . * : : :: : : :::. *: : .::::: :****:::: : :* ***:* ** **::* *:** *::: ::*:: . * . : .::*: * * :: : **.:: :*: * .* ..: * * .:. : * . *. :: **: : :* :** * . * ::.::* . .: . . : . . :. .: ..: . .* : : . . .:. :: : . ::: : . . : . . * .* :. :. * : * * . : .**:*.* : . . : . :. :: . . .: .*: ", "identical_positions": 68, "similar_positions": 161, "identity": "9.07%" }, { "cls_id": "homologset.agr.MGI:1933141", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACP2-1", "uniprot_id": "SIM12_RAT", "id": "D4ACP2-1", "name": "Small integral membrane protein 12", "aln": "MWPVLWTVVRTYAPYVTFPVAFVVGAVGYHLE-WFIRGKDPQPVEEEKSILERREDRKLDEMLGKDHTQVVSLKDKLEFAPKAVLNRNRPEKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78RX3-1", "uniprot_id": "SIM12_MOUSE", "id": "Q78RX3-1", "name": "Small integral membrane protein 12", "aln": "MWPVLWTVVRTYAPYVTFPVAFVVGAVGYHLE-WFIRGKTPQPVEEEKSILERREDRKLDEMLGKDHTQVVSLKDKLEFAPKAVLNRNRPEKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EX1-1", "uniprot_id": "SIM12_HUMAN", "id": "Q96EX1-1", "name": "Small integral membrane protein 12", "aln": "MWPVFWTVVRTYAPYVTFPVAFVVGAVGYHLE-WFIRGKDPQPVEEEKSISERREDRKLDELLGKDHTQVVSLKDKLEFAPKAVLNRNRPEKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BKW8-1", "uniprot_id": "SIM12_DANRE", "id": "Q5BKW8-1", "name": "Small integral membrane protein 12", "aln": "MWPIFWTAMRTYAPYVTFPVAFVVGAVGYHLE-WFIRG-TPNTPGEERGIAELREDRKLEELNGRDSTQVLSLKDKLEFTPRAVLERNRAVKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6IGN6-1", "uniprot_id": "Q6IGN6_DROME", "id": "Q6IGN6-1", "name": "Small integral membrane protein 12-A", "aln": "MWPIVMALIRRNAVYITLPIAGVVGFIGYNIESWISDKYTPYSP----SIQELRAKRLTEESLNTDAANVEKLRLSSPVLERNLSPSLQPKA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:. : :* * *:*:*:* *** :**::* *: * . .* * * .* :* . * ::* .*: . . : : :. ", "identical_positions": 25, "similar_positions": 26, "identity": "26.88%" }, { "cls_id": "homologset.agr.MGI:1933148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIU1-1", "uniprot_id": "ABTB1_RAT", "id": "Q5XIU1-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "aln": "-------MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVRYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHS-DVVF-VVHGKPFRAHRCILGARSTYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTG--RLDIGVEHVSDCERLAKQCQLWDLLDDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRADMALLADCALPPELRGDLGELPFPCPDGFSSCPDICFRVADSS-----FLCHKAFFCGRSDYFRALLDDHFRESEEPVASGDP--------PVVTLHDISPDIFTHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKRLCGRSLAQ---LLEEDSVVGVWRIAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVREEAAAVAARQETDSIPLVDDIRFHVASTVQTYS------------------AIEEAQQQLRALENLLVSIGLDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LJ2-1", "uniprot_id": "ABTB1_MOUSE", "id": "Q99LJ2-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "aln": "-------MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVRYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHS-DVVF-VVHGKPFRAHRCILGARSTYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTG--RLDIGVEHVSDCERLAKQCQLWDLLDDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRADMALLADCALPSELRGDLGELPFPCPDGFSSCPDICFRVADSS-----FLCHKAFFCGRSDYFRALLDDHFQESEEPAASGDP--------PVVTLHDISPDIFIHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKRLCGRSLAQ---LLEEDSVVGVWRIAKMFRLARLEDQCTEYMAKVIEKLVEREDFVEAVREEAAAVAARQETDSIPLVDDIRFHVASTVQTYS------------------AIEEAQQRLRALEDLLVSIGLDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969K4-1", "uniprot_id": "ABTB1_HUMAN", "id": "Q969K4-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "aln": "-------MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHS-DVVF-VVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTG--RLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCS-----FLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGP--------PAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPGLKRLCGRSLAQ---MLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYS------------------AIEEAQQRLRALEDLLVSIGLDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F920-1", "uniprot_id": "E7F920_DANRE", "id": "E7F920-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "aln": "-------MDAVDLFSSCRKGDIARVRYLVEQRDVELNIRDKWDSTPLYYACLCGHEELVQYLLANGAKCEANTFDGERCLYGALSDAIRRLLKEYKRITAKAMQRDYYDQFLQTLLEQGNYS-DVTF-VVHGEMFKAHRCILSARSEYFAHMLETKWKGKSAIALKHPLVNPAAFGAIMQYFYTG--RLDIDVNYVEDCKRLAKQCKIGELIEELEVKCKQVYEFVSNKPGTCVKVLTLDP--HDFQLQDGMALLADSALPAELRVGYGQLPFDLTDSFPSYPDICFRVEGYD-----FLCHKAFFCGRSDYFKALLEDHFSEGETLQTHPSI--------PVITLHDVSHDLFTRILYYIYSDNTQLSHENVYEVLCVADMYLLPGLKRLCGRTLAA---LLNEENVLHMWRTAKLFRLSRLEDQCTEHMAKIIERLVERPEFADMIREDAGNVAARQETDSIPLVDEIRFHIASNVQTYS------------------AIEEANQKLSALELLLASIGLEC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40560-1", "uniprot_id": "YIA1_YEAST", "id": "P40560-1", "name": "Ankyrin repeat-containing protein YIL001W", "aln": "MADKLMDKNFEELCYSCRTGDMDNVDRLISTG-VNVNSVDKFDNSPLFLASLCGHEAVVKLLLQRGAVCDRDRYEGARCIYGALTDTIRDTLLSYDISKAVDVKQPFATHISSMYNDEGFLKRDITFRVSNGKLFTAHKFLLCARSEILAEKMVNEWAKHEIVSL---EVRPDIFDIFLKFLYLIPILHQIEPGQYEELIELSSKFDIELLPEFLDKARHTADPTEKSR-----LMSDYQYKFTEVARSQLLIFVNNCIFRSTVDLANSERRVFSLMNCPAYPDVQLMVKNRNGAIRIYPCHLAVLS-RAEYFKVMFTNNFKEKVTYIKAKHVTGKYNSIIPQLTLPNCEFEVAEIILRYLYADNTDIPWMYAVDVLLLADILLEDRLKTIASTIITQSKEFIQQYNVFDVLYLSWEIGVERLEQFAAKFIAIHLQELYKDPEIKRAIMLSSQRISLRQETDTIELVDDIRYYLLRKYSFEPDDVELFENQDDLEYLKQVGYLEYRKDMGMLDNILADLELDV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* ***.**: .* *:. *::* **:*.:**: *.***** :* ** .** *: : ::* **:****:*.** * .*. .* :: : .: . ::* . *:.* * :*: * .*: :* *** :*. : .:* :. : * :.* *. :::::* :* .: .*:.: .: * . *: . . .: : : : : :: :. : . : : . . : **: : * . . : ** *.:. *::**:.:: ::* * * :** . . :: :* *:*:*:*::. . :** :**: * ** :.. :: :::: .*. : : : : ***: .::.:* ::.* : :: : .: :: *****:* ***:**::: . . . . * .: : *: :*..: *: ", "identical_positions": 108, "similar_positions": 170, "identity": "20.65%" }, { "cls_id": "homologset.agr.MGI:1933153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32ZI4-1", "uniprot_id": "DEFB3_RAT", "id": "Q32ZI4-1", "name": "Beta-defensin 3", "aln": "MRIHYLLFSFLLVLLSPLS-AFSKKVYNAVSCMTNGGICW-LKCSGTFREIGSCGTRQLKCCKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPV9-1", "uniprot_id": "DEFB5_MOUSE", "id": "Q9EPV9-1", "name": "Beta-defensin 5", "aln": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICR-YLCKGNILQNGSCGVTSLNCCKRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15263-1", "uniprot_id": "DFB4A_HUMAN", "id": "O15263-1", "name": "Defensin beta 4A", "aln": "MRVLYLLFSFLFIFLMPLPGVFGG-IGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ****:**:::* **. .*. : :.*:* *.** * : *:** :***: ", "identical_positions": 23, "similar_positions": 18, "identity": "35.38%" }, { "cls_id": "homologset.agr.MGI:1933154", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPH0-1", "uniprot_id": "S26A5_RAT", "id": "Q9EPH0-1", "name": "Prestin", "aln": "---------------MDHAEENEIPAETQKYLVERPIFSHPVLQ-ERLHVKDKVTDSIGDKLKQAFTCTPKKVRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVR-----------------------------LVPDDIVIPGGVNATNGT--EARDA-------LRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGG-KEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYTVLGQLPDT-DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPAIIMGARRKAMRKYAKEVGNANIAN---------ATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGEN-IHTVILDFTQVNFMDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTSNRFFENPALKELLFHSIHDAVLGSQVREAMAEQETTVLPPQEDMEPNATPTTPEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NH7-1", "uniprot_id": "S26A5_MOUSE", "id": "Q99NH7-1", "name": "Prestin", "aln": "---------------MDHAEENEIPAETQRYYVERPIFSHPVLQ-ERLHVKDKVTESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVR-----------------------------LVPDDIVIPGGVNATNGT--EARDA-------LRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGG-KEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQLPDT-DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPALIMGARRKAMRKYAKEVGNANVAN---------ATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGEN-VHTVILDFTQVNFVDSVGVKTLAGIVKEYGDVGIYVYLAGCSPQVVNDLTRNNFFENPALKELLFHSIHDAVLGSQVREAMAEQEATASLPQEDMEPNATPTTPEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58743-1", "uniprot_id": "S26A5_HUMAN", "id": "P58743-1", "name": "Prestin", "aln": "---------------MDHAEENEILAATQRYYVERPIFSHPVLQ-ERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVR-----------------------------LVPDDIVIPGGVNATNGT--EARDA-------LRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGG-KEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPET-DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMAN---------ATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDN-VHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALAEQEASAPPSQEDLEPNATPATPEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T2C4-1", "uniprot_id": "S26A5_DANRE", "id": "Q7T2C4-1", "name": "Prestin", "aln": "---------------MEHVTVSEEPSATLMYHVERPIFSEAYIDSELLHKRKKTPKPYKLRVAEHLCCSSEKVKSVVFGFLPILTWLPSYPLKEYLFGDIVSGISTGVMQLPQGLAYAMLAAVPPVFGLYSSFYPVLLYTFFGTSKHISIGTFAVISLMIGGVAVR-----------------------------EAPDSMFMVNGTNSSLVVNIEARDS-------RRVEVVVALTTLVGIIQFVLGLLRFGFLAIYLTEPLVRGFTTAAAVHVSVSQLKYLLGVKTARFNGPLSVVYSLDAVLRNIADTNIVTLIIGLGCTVFLYII-KQLNERFKKKLLIPIPGEIIVVIVSTGISYGMLMSENYGVDVVGKIPTGLLPPKVPDFSVFPNLFADAVPIAVVGFSITISLAKTFALKYGYSVDGNQELIALGLCNFVSSFFHTFVVTASMSRSLVQESTGGHTEIAGLLASLLVLLVVVAIGFVFQPLPTTVLAAIIMVNLLGMFKQTRDIPVLWRKSKIELAIWLVSFFASVLLGLDYGLAVAMAFAILTVIYRTQRPKNVVLGQIPDT-GLYFDVDEYEEAEECSGIKIFQSNSSIYFANSELYVKALKAKTGIDPEKLLDAKKLQLKYAKRDTEGTKTVNQGSLLKKNAVVLLDMELGVTHEVLNGPQKPKHVHTNGQMTEKHIESESEDEFFLQRLTPIHSVILDFTPVNFIDSVGAKTIKSVIKEYATVDVKVVLAGCSRTLLSELRTLQFFSEPVTPDLIFPTIHDAVLQCKRWRDLPVHPNIH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVM6-1", "uniprot_id": "Q9VVM6_DROME", "id": "Q9VVM6-1", "name": "", "aln": "MPSDKESPETKPLNNNNTNGNGGSVPSKPKIQPKYSIHRDVLTHEVVIKQTGYAARDKSIPSSLRNCWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLD-----------------------------------------KIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSE--GPFEIFPTLHDCVEYANACRTA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : .*. . . :: .. . :. :. .:** *** * :. : **:::*::..::::*:*:*:.:**.*.. *** :.:**: * *:***:*****.*** *:* . *. :. : ....:: : :: :::*. ::: **::: :.. *:* :: *:****.******* ** .: ** ::*:.. *..* :.::*: *::.: : *: .: . : :: : :: *:.:* *:* *:: *: .* ** : : .*.*: **.:* ** * * .:. : .*::.**:* :*: :*:. *:* *:**.* ****:*:*: * :.. * : ::.*:***::*: *** :::*. ::: ::::.:: * .*..** **:.:::* * ** * :: : : .*:*: *: :*.. :::.:* ** .: :::*:: : * :** :*:: .:*:*:: :.:. : . ::**: ...: :*.* :: ** .*:: . : . .:. . . . : : : .: ::***: :..:* .* :*: .: ** . : **. : . * :.: :* ::**.* .: . ", "identical_positions": 158, "similar_positions": 273, "identity": "19.51%" }, { "cls_id": "homologset.agr.MGI:1933155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ70-1", "uniprot_id": "B2RZ70_RAT", "id": "B2RZ70-1", "name": "", "aln": "----MGNHLTEMAPTASSFLPHFQALHVVVIGLDSAGKTSLLYRLKFKEFVQSVPTKGFNTEKIRVPLGGSRGITFQVWDVGGQEKLRPLWRSYTRRTDGLVFVVDSAETERLEEARMELHRISKASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELA-----------------------------------------------------------AATLT-------------------------------------------------HVQGCSAVDGLGLQPGLEHLYEMILKRKKAPRSSKKRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PE9-1", "uniprot_id": "ARL4D_MOUSE", "id": "Q99PE9-1", "name": "ADP-ribosylation factor-like protein 4D", "aln": "----MGNHLTEMAPTASSFLPHFQALHVVVIGLDSAGKTSLLYRLKFKEFVQSVPTKGFNTEKIRVPLGGSRGITFQVWDVGGQEKLRPLWRSYTRRTDGLVFVVDSAETERLEEARMELHRISKASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELA-----------------------------------------------------------AATLT-------------------------------------------------HVQGCSAVDGLGLQPGLEHLYEMILKRKKAPRSSKKRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49703-1", "uniprot_id": "ARL4D_HUMAN", "id": "P49703-1", "name": "ADP-ribosylation factor-like protein 4D", "aln": "----MGNHLTEMAPTASSFLPHFQALHVVVIGLDSAGKTSLLYRLKFKEFVQSVPTKGFNTEKIRVPLGGSRGITFQVWDVGGQEKLRPLWRSYTRRTDGLVFVVDAAEAERLEEAKVELHRISRASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELA-----------------------------------------------------------AATLT-------------------------------------------------HVQGCSAVDGLGLQQGLERLYEMILKRKKAARGGKKRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H9XVM3-1", "uniprot_id": "H9XVM3_DROME", "id": "H9XVM3-1", "name": "ADP-ribosylation factor-like protein 11", "aln": "MGATMVKPLVKNGNILDALPSQVATLHVVMLGLDSAGKTTALYRLKFDQYLNTVPTIGFNCEKVQCTLGKAKGVHFLVWDVGGQEKLRPLWRSYTRCTDGILFVIDSVDTERMEEAKMELMRTAKCPDNQGVPVLILANKQDLPNACGAMELEKLLGLNELYNPVPNISMPSSSDSSPTINLIGCRVSNQSITDKSLEEKKESHLHSSMIHIKPALESKDHNSTLSGGALTAFIYPQSHNNSAVLDQKNPQDVKNGFHNKKMNRSSSNSVQFRGWYIQPTCAITGEGLQEGLDALYDMILKRRKINKSNKRNL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *.: . .:: .:. :****::********: ******.:::::*** *** **:: .** ::*: * ******************* ***::**:*:.::**:***::** * ::..********:****** *.* .* *:** *.:.** :**: ::* .*: * *** **: **:*****:* :..*:. ", "identical_positions": 107, "similar_positions": 61, "identity": "34.19%" }, { "cls_id": "homologset.agr.MGI:1933156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63448-1", "uniprot_id": "ACOX3_RAT", "id": "Q63448-1", "name": "Peroxisomal acyl-coenzyme A oxidase 3", "aln": "MGSSSERRD-------SVLW--------------------------SDIPKG-PLSAYRARASFNSKELMLFWDGQDVLDFKKTIFSTLENDPLFARPFGADLPLEKERELNFLRCKRVFEYGFFN----AEDMLKNPLKILVLMNCLGMYDWSLANKCVLHMLVFGSTIIGSGSEHHFKYLEKIYNLEIFGCFALTELSHGSNTKAMRTTAHYDPATQEFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYTPDGQCRGLHSFLVQIRDPKTLLPMPGVMVGDMGKKLGQNGLDNGFAMFHKVRIPRQNLLDRTGNVTSEGHYHTPFKDVRQRLGASLGSLSSGRISIISISVVNLKLAVIIAIRFSATRRQFGPTDK-EEIPVLEYPLQQWRLLPYLAAAYALDHFSKTIFLDLIELQRAGKV-GTTVTGRQSSGREIHALASAGKPLASWTAQRGIQECREVVGGHGYLAMNRFGELRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEHPLQDGAHFTSPLKTVNFLEAYPGILGQKFM-ASSKADWLDSEAPLAAYRWLVCYLLRESHQRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHTHSSSVPPSLRTVLGRLSMLYGLWCLSQHTALLYRGGYIS-GEQTGKAMEDAILMLCVQLKDDAVALVDAIAPSDFVLGSPIGRADGELYKNLWAAVLQQSGVLERAAWWPEFTANKSVANRLKSQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPL9-1", "uniprot_id": "ACOX3_MOUSE", "id": "Q9EPL9-1", "name": "Peroxisomal acyl-coenzyme A oxidase 3", "aln": "MGSLPEEKD-------SALW--------------------------SDTPKG-PLSAYRARASFNSGELLLFWDGQDVIHFKKTIFSTLENDPLFARSYGADLPLEKLRELNFLRCKRVFEYGFFK----VEELLKNPLKILVLINCLGMYDWSLANKCVLHMLVFGTTVFVSGSEKHFKYLEKIYSLEIFGCFALTELSHGSNTKAMRTTAHYDPDTQEFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYMPDGQCHGLHSFLVQIRDTKTLLPMTGVMVGDIGKKLGQNGLDNGFAMFNKVRIPRQNLLDRTGNITSEGTYNSPFKDVRQRLGASLGSLSSGRISIISMSVVNLKLAVSIAIRFSATRCQFGPTDK-EEIPVLEYPLQQWRILPYLAAAYALDHFSKTIFMDLIEVQSARLR-GDHSDQQAELGREIHALASAGKPLASWTAQRGIQECREACGGHGYLAMNRFGDLRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEPPLQDGAHFTSPLKTVDFLEAYPGILGQKFL-GSSKADWMDSAAPLAAYRWLVCYLLQESHRRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHIHSSGLSPSLRTVLGRLSTLYGLWCLSQHMALLYRGGYIS-GEQTGRAMEDAILTLCEQLKDDAVALVDVIAPSDFVLNSPIAKADGELYKNLWAAVLQQNGVLERAAWWPEFSANKSVADRLKSQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15254-1", "uniprot_id": "ACOX3_HUMAN", "id": "O15254-1", "name": "Peroxisomal acyl-coenzyme A oxidase 3", "aln": "MASTVEGGD-------TALL--------------------------PEFPRG-PLDAYRARASFSWKELALFTEGEGMLRFKKTIFSALENDPLFARSPGADLSLEKYRELNFLRCKRIFEYDFLS----VEDMFKSPLKVPALIQCLGMYDSSLAAKYLLHSLVFGSAVYSSGSERHLTYIQKIFRMEIFGCFALTELSHGSNTKAIRTTAHYDPATEEFIIHSPDFEAAKFWVGNMGKTATHAVVFAKLCVPGDQCHGLHPFIVQIRDPKTLLPMPGVMVGDIGKKLGQNGLDNGFAMFHKVRVPRQSLLNRMGDVTPEGTYVSPFKDVRQRFGASLGSLSSGRVSIVSLAILNLKLAVAIALRFSATRRQFGPTEE-EEIPVLEYPMQQWRLLPYLAAVYALDHFSKSLFLDLVELQRGLAS-GDRSARQAELGREIHALASASKPLASWTTQQGIQECREACGGHGYLAMNRLGVLRDDNDPNCTYEGDNNILLQQTSNYLLGLLAHQVHDGACFRSPLKSVDFLDAYPGILDQKFE-VSSVADCLDSAVALAAYKWLVCYLLRETYQKLNQEKRSGSSDFEARNKCQVSHGRPLALAFVELTVVQRFHEHVHQPSVPPSLRAVLGRLSALYALWSLSRHAALLYRGGYFS-GEQAGEVLESAVLALCSQLKDDAVALVDVIAPPDFVLDSPIGRADGELYKNLWGAVLQESKVLERASWWPEFSVNKPVIGSLKSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PGE7-1", "uniprot_id": "A0A8M1PGE7_DANRE", "id": "A0A8M1PGE7-1", "name": "Acyl-coenzyme A oxidase", "aln": "MSDPAITDA-------KYVLGDK------------------MDEGIPDFPNG-PLDIYRKKASFSWKDMMRFLEGDELIAFKQHVFRTLERDPLFARQPGEDVPVEQKRELTFLRCKQLFKYDFIT----REELMQNPWKMIVLNDCLGMYDWSLCAKYFLNKGMFGATVLNTGSQRHLKFVKDIERMMTFGCFSLTELSHGSNTRALRTTAKYDPNTQEFVINSPDFEAAKFWVGNLGKTATHSVVFAQLYTPDGKCHGLHSFIVQVRDPKTLLAMPGVMVGDMGKKLGQNGLDNGFAVFHNVRIPRENLLNKTGDVAPDGQYVSPFKDPNKRFGASLGALSGGRVGITRMALVNLKLAVTVAVRFSATRRQFGPKED-EEIPVLEYQLQQWRLIPFLAAVYALEHFTKSFSRNFVEFQMGLLM-KDKSDRQAELGREIHALSCASKPLGSWTAQRGIQECREACGGHGYLAMNRLGDMRDDNDPNCTYEGDNNVLLQQTSNYLLSWIQHKQEGNGRIESPLETVNFLDDMSSILQSKFT-VGSVEECMNSAVPLAAYKWLVCFLLGESQRKLFQEKSSGLGDFEARNNSQVYYCRTLAIAFIEHTVLQRFHDLIQDEQTPAALRSVLGRLCALYGLWTLTNHMAILYQGGYFS-GGQPVDFIQTAILTLCGQLKDDAVALVDVFAPPDFILNSPIGKADGELYKNLWSTVMQGKNVLERPSWWAEFCSDKPVVGSLRAKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z028-1", "uniprot_id": "B7Z028_DROME", "id": "B7Z028-1", "name": "Acyl-coenzyme A oxidase", "aln": "MASGVGDGDGGDQNGLNSLLTALGDYYSGRREEKAAANIYDDKRIFPDFRSG-PLEEYRERASFCYKRMNVVLEGEDHIRLKHKVWQWMEQHPDYQREPGSD--LERTREMANKRQHLLWEQQFYG----VNEYLGTPHLLLAFGQAIFSYDFSTSVKFGLSTGMFPSTLVSNGSGRLGKYVAKIADNRILGAYALTEISHGTNALGMRTRATYDVKRQEFIIHTPDFEAAKCWVGNLGKTCTHAIVYAQLYVPDDKHQGLQAFLVPIRDERTLLPFPGVTVGDMGEKIGLNGIDNGFVMFNQYRIPKANLLSKTGDIDAQGNYTSKIKDERKRLGASLGALSVGRVNITAITYVALSKAVTIATRYAASRRQFGPTNSPAEWPVIEYQSQQYRLIPHLATTIALRVATLWIGKENVDLTMKGFT-GEDTS---QAGMEIHAISSALKPVATWAARDGIQECREACGGHGYLKSSGLGELRNDNDANCTYEGENNTLIQQASNWLISLQRN--NADFVAVSPLETVSFLKDMDTILQSKGQ-ERTPAEVLDPLNLLNALNWLTVWQLDTTVKRVEEQQREGKDAFETRNNIQVFAAQKLSIIYGERTIYYVFYKFVIG-LPDSAEKKVLQQVLSFYGAHLVTKYSAAFYRGGYFRENSNQLELYEQGILALLPLLKNEAIALVDAIAPTDFILNSPLGMSDGNVYQHLQRTLVSTPGVYERPHWWRDVTYKDYLK---RAKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIX4-1", "uniprot_id": "Q9VIX4_DROME", "id": "Q9VIX4-1", "name": "Acyl-coenzyme A oxidase", "aln": "MGSED-----------TSFI--------------------------PDLPSGGPLAVYRKRANFDWKRLRLIFEKEQGLRIKYKVWRRLENDPLFAH-PSRTLPMDEQKRLCAMQVNRMKHLDLVPKEIESLSFSAKTKYLMYINEALACYSPSLSVKIALGVGLFNNAIRAMGTEKHQKYIEAAWNREVITCLAITELSHGSNTKSIRTTATYDPTTQEFVINTPDFEAAKCWVGNLGKTATVAMTFANLYTADGQNHGLHGFLIPIRDPKTLLSYPGVLVGDIGEKCGLNGIDNGFVVFTNYRIPRDNLLNRTSDVTPEGVYESVFTEPGKVLGAALESFSAGRIGIMQESANTLCSAAVIAVRYSAVRKQFGPERHGEEMAILEYQLHQYRIFPYLAAACVQKIATEELTSTYMEIIARSQADSNGFDVLTQNAAEIHALISSSKPLITWAARDAIQEAREACGGHGYLQAAKLGQMRTDHDPLCTYEGDNNVLGQQASNWLLRQWSAK-----ELETPIGSVKFLERRSELLALNYASLAQKTPIASWQFSLRCYEWLLCHLMAKTTAHIEGQLAAGSSKFEARNNSQVAGARELSLAYAEYYALTRYVDHVSTLTVEAPYASVLRLLFDVYAMWLLEKHMTTFYVGGFAA-GRDFSAAVRQLLLDSCLKLKDVAVSVADAISPPDFALNSVIARADGLLYENLQNEFMTNEGAFQRPSWWRDVIIP-----QAQSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. . . .: * ** ** :*.* : . : : : :* :: :*..* : : . ::. :.: : : : . : . .. : : :.: *. * . * * :* :: *: : .:: : . ::**:***:*: .:** * ** :**::::******* ****:***.* ::.:*:* ...: :**: *:: :** :***. .** ***:*:* * **:****.:* : *:*: .**.: .:: .:* * : :.: : :**:* ::* **:.* : * *. :* *::* * **** * .::** :*:*::*.**:. . : : ::. . . ****: .: **: :*::: .***.**. ****** :* :* *:*. *****:** * **:**:*: :*: :*.**. :* : . * . .** : : : : . **:**: ** : *:: : * : . .. ** : .*. : .: : :* **: . : . :* **: *:::.*.::*.** *.* :. :** :*::* .: . :*. ** :. :::*", "identical_positions": 176, "similar_positions": 217, "identity": "23.72%" }, { "cls_id": "homologset.agr.MGI:1933157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68907-1", "uniprot_id": "PZRN3_RAT", "id": "P68907-1", "name": "E3 ubiquitin-protein ligase PDZRN3", "aln": "MGFELDRFDGEVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPSRCRGRLSAKELNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRHAGCGQLLLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGALHKALKKEALRAGKREKSLLAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGG-GEETKSLTLVLHRDSGSLGFNIIGGRPCVD-NQDGSSSEGIFVSKIVDSGPAAKEGGLQIHDRIIEVNGKDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPASESQLVDTGTQTDITFE---HIMALTKISSPSPP----VLGPYLLP-EEHPSSHEYYDPNDYMGDIHQDMDREELELEEVGLYRMNSQDKLGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASVLQQKKHEEDGGTTDTATILSNQHEKDSGVGRTDESTRNDESSEQENNGEDATASSNPLAG-QRKLTCSQDTLGSGDLPFSNESFISADCTD-VDYLG-IPEDECERFRELLELKCQVQSTSPYSLYYPSSPLDAAGKGDP--ESVDKELELLNEELRSIELECLSIVRAHKMQQLKEQYR-ESWMLHHSGFRNYNTSVDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRVAEG----SSEGATANMEAYRPSPKNLLAITEDPEVSTPNYNPGAKELDPSQALEIKERRVSDGSRSPTASPKLGSAYLPSYHHSPYKHAHIPAHAQHYQSYMHLIQQKSAVEYAQSQMSLVSMCKDLN-SSNSAEPRMEWKVKIRSDGTRYITKRPVRDRLLRERALKIREERSGLTTDDDAMSEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQ-QASDDRKEMNILELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZS0-1", "uniprot_id": "PZRN3_MOUSE", "id": "Q69ZS0-1", "name": "E3 ubiquitin-protein ligase PDZRN3", "aln": "MGFELDRFDGDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLSAKELNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRHAGCGQLLLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGALHKALKKEALRAGKREKSLVAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGGKGEETKSLTLVLHRDSGSLGFNIIGGRPCVD-NQDGSSSEGIFVSKIVDSGPAAKEGGLQIHDRIIEVNGKDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPASESQLVDTGTQTDITFE---HIMALTKMSSPSPP----VLDPYLLP-EEHPASHDYYDPNDYMGDIHQDMDREELELEEVGLYRMNSQDKLGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASVLQQKKHEEDGGTTDTATILSNQHEKDSGVGRTDESTRNDESSEQENNGEDATASANPLAG-QRKLTCSQDTLGSGDLPFSNESFISADCTD-VDYLG-IPEDECERFRELLELKCQVQSASPYSLYYPSSPLDAAGKSDP--ESVDKELELLNEELRSIELECLSIVRAHKMQQLKEQYR-ESWMLHHSGFRNYNTSVDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRVAEG----SSEGATANIEAYRPSPKNLLAITEDPEVSTPSYNPSAKELDPSQALEIKERRGSDGSRSPTASPKLGNAYLPSYHHSPYKHAHIPAHAQHYQSYMHLIQQKSAVEYAQSQMSLVSMCKDLN-SSNSVEPRMEWKVKIRSDGTRYITKRPVRDRLLRERALKIREERSGLTTDDDAMSEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQ-QASDDRKEMNILELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPQ7-1", "uniprot_id": "PZRN3_HUMAN", "id": "Q9UPQ7-1", "name": "E3 ubiquitin-protein ligase PDZRN3", "aln": "MGFELDRFDGDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLSAKELNHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRHAGCGQVLLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGALHKALKKEALRAGKREKSLVAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGGKGEETKSLTLVLHRDSGSLGFNIIGGRPSVD-NHDGSSSEGIFVSKIVDSGPAAKEGGLQIHDRIIEVNGRDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPPSESQLVDTGTQTDITFE---HIMALTKMSSPSPP----VLDPYLLP-EEHPSAHEYYDPNDYIGDIHQEMDREELELEEVDLYRMNSQDKLGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASVLQQKKHDEDGGTTDTATILSNQHEKDSGVGRTDESTRNDESSEQENNGDDATASSNPLAG-QRKLTCSQDTLGSGDLPFSNESFISADCTD-ADYLG-IPVDECERFRELLELKCQVKSATPYGLYYPSGPLDAG-KSDP--ESVDKELELLNEELRSIELECLSIVRAHKMQQLKEQYR-ESWMLHNSGFRNYNTSIDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRAAEGISCPSSEGAVGTTEAYGPASKNLLSITEDPEVGTPTYSPSLKELDPNQPLESKERRASDGSRSPTPSQKLGSAYLPSYHHSPYKHAHIPAHAQHYQSYMQLIQQKSAVEYAQSQMSLVSMCKDLS-SPTPSEPRMEWKVKIRSDGTRYITKRPVRDRLLRERALKIREERSGMTTDDDAVSEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQ-QAADDRKEMNILELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDW2-1", "uniprot_id": "PZR3B_DANRE", "id": "E7FDW2-1", "name": "E3 ubiquitin-protein ligase PDZRN3-B", "aln": "MGFELDRFKGAVDPDFKCNLCNKVLEDPLTTPCGHVFCAGCVLPWVVQQSSCPVKCQ-RISTKELNHVLPLKNLILKLDIKCDNHARGCEKIVKLQHLAEHAEMCDYSPAKCRNKGCSEVLNLKDMDAHMRESCDYRAVGICESGCGLMLTHKEQKLDNHCCLKALKAHNGALQGKVVTLDKELKKQALKSTKREKSLLAQLSAVHNELQMTALKYQKKFTEYSARIDSLSKSLSPSPPCKGGETKSVTAILHRESGSLGFNIVGGRPCVD-NKDGTSNEGIFVSKIVEKGAADKEGGLQIHDRIMEVNGKDLSKATHDQAVEAFRMAKEPIMVQVLRRAPRPKPTGPTGEGQVVDISTQTDITFQ---HIMALSKLPTSSTPV--DVLEQYLLP-EGHSPAHEYFDPNDFLEGMQHEIEREELEYEEVDLYRTNIHDKLGFTVCYRTDDEDETGIYVSEIDPNSIAAKDGRIREGDRIIQINGIEIQNREEAVALLTSEEHPNVCLLLARPEIQLDEGWMDDDRNDYLDDLHMDMLEQQHHQAMQFTASMLQQKKHEEDGGTTDTATLLSHHHEKDSGVGRTDDSTRNDESSEQENLADDQTSASTTLGS-RRRLAYSQDTLGSGDLPFSSESFISADYAD-AEFLGDFPADECERFRELLELKCQMQSAGSSGTPDQSLLWPSGGQGGVGEEGVDKELELLNEELRSIELECLSIVRAHRMQQLREQCREQSWMLHNSGFRNYNTSVDARRHELADISELPEKSDKDSSSAYNTGESCRSTPLTLELSPDNSLRRGNES---QAEAGASSSTSGPSRILKPLLSPVQEACSPTRGRPTLLKESEVGTQPEVRERK---GGRHAHP-------------QSPYKHAHIPAHAQHYQSYMQLIQQK-SVEYAQSQMSLVSMCRDPV-TSADLGPKMEWKVKIRSDGTRYITKRPVRDKLLKERALRIREERSGMTTDDDAVSEMKMGRYWSKEERKQHAVRAKEQRQRREFMKQSRMDCQKELGVTTEDKKDVNIIELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSLLSVTTV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1QLC6-1", "uniprot_id": "A0A8M1QLC6_DANRE", "id": "A0A8M1QLC6-1", "name": "", "aln": "MGFDLDRFEGPVDPDLICKLCGKVLEDPLATPCGHVFCAACALQWLSKVNSCPVQCQ-KISIKELNQVLPLKNLILKLDIKCDHRERGCVRVMKLQHLAEHAEMCDFSPVRCRNEGCDAVLNLKDAASHLQETCEYRALEVCKNGCGLMLTPKEMSG-EHSCLQALKAHGGLLQTKAQSLEKELKRQALSFSKRERSLLSKLSALHCELHITALTFQKKITEYKSRIDALTNSWMP--RDQGEETMSFKVTLHKTSGSLGFSIIGGRLCEELDEHGDFSDGIYISKIVENGAADKAG-LCVHDRITKINGRSLSIATHDQAVEAFQTTEDPIEVEVLRRVT-HKTCKPLKPVCGMDNSTQTNITLQYLKHIETMAQLPSPTTPPSMAILNGFCSPKQCQKTRCDSPYPPDFDDGVEKDIESKGLEYEEVDLQRKNIQDKFGLMLCYKMDDE-KTTIYVSKIDPEGVAAKDGRIQEGDQIIQINGEEVQSHEVAVALLTKEDSKNVAILVARPERQ-DVCWLEED-------LKLGIFEQLNDKVKEFDTSMLQQSTREEDGGTTDTATLLSNHHEKDSGVGRTDESTRNDESSEQDILGDDQNSLCDTLPENHKKFSYSQGTLECGDINLSNESFLSVDNGDNGNFIG-IPGTACERFRKLLELKCLMNSNNLQGLLEHDATQYGKRITTN---CDDQEDQMLNKQLLNIELECLSIIQAHRLQAEDSGPQ-----TTDPSTKHFIEQLNDKVHQDLLNNKVDN---ECSTSAYNTGESCWSLQPALESHSPESQRMLIAD---KGKGSPMIRRNSTTACSKHNLSPIREISPTKS----LAGDPEVTNQGKRKQSK----RKNPRS-----------LHHSSYKNTYIPAHAQHYQSYMQLIQQKSAVEYAHSQVSIASLCKNPENTTTDSRLKMGWKVKVRNDGTRYVTRRPIRDQLLKERALRIREERCSITTDDDAGSELKLGRYWNKKERKQHAVQAKEQQQQRELMKQCYMENKGKT--GTLNNKEPDIIQLSRKKMMKRRNKRIFDNWMTIQELLTHGTKSTDGTKLYNSFLSVTTV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MR31-1", "uniprot_id": "SLIP1_DROME", "id": "Q8MR31-1", "name": "Slo-interacting protein 1", "aln": "---------------------------MSIADVEYEYVVLKINGYDISHLSRYEAVQKFLQSKETLVVEIRRQKHNALDLELKHGSN--AKISKVDNPGELSVLTDKSAEGTITAASASQQINCPSSTSLKEIETKTPVVLTLR---------------------ARSHEDRLGSLQAASKETQTQSVVGTDVLKDNDLVNTITDNFIEHEHHLFEQCLEPEIDIEEVTLVKGVEQSSSNQIGLIVTSSGIQQSSTDTNKGDILG--------NVLEHSEDVFISGVQPESIAYRDGRLRQGDQILRINGLDVK-------------NQEELETQIARSSTSVTLLVS--RILYPEDDDDEDIHFEY-----------------------------------ANTFLPDDYTN-VVDKLDKVLLTHVKS-LEELSNKSAMQSDECYHIPEK----------------------NSSDSNVKISSLAKN--------IIEQSTKSCSKIKLRPNAN----------LDYKKKFNLPLSQEEVHLQYEYDESEHIYETIPEDSESEPVYCSPYQRSNDKTSIGCSSPIASRPAESLERTMQQQTQRVAQWLGL-KPQYQKTRQTLVGRPPP-----------------LKLVQQPTCSRVFTLRSTLTNTSASSSSGVAYSS----------------YGQNNVVTGNAAAPGEEVDNSSSAYNTGDSNNSAS------PHQNTTNPDEAIATGRKLDSTVIDSPNDHLDATG---------VSTMLLLPFGKSGRIGLCSSN-----LPTAYVSERYTNVGSENEIHPLKS-------------DIEILRVKP-----------------------------TDDSYSHCPQFNAPNLSSYHFVSSQEVANRCHISTSLQKNATLLN-GESAEEIPMVWKVKRRPDGTRYIVKRPVRNRPQVALRKNMRYN-EVTTTEDDTISEVKIGRYWTKEERKRHIERAREKRHHQTQQQQQ---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : . * : :. ** * :. **:: . :: *::. * * :. .. : ::: .: ::* . * : .: .:..: : . : : : : : * * .* . . :* . : . : :.: .*:* . .:.:::* : .. * : * * *:* .:** .:. :: : .:: * . . . : . : :* :: : * *: : ..:: * : * . . :. : **: :: ...* ::*.. : : .:. . . : **: : ::: : :: . :: * .. **. : . :: :..:.:* :. : . .* : :: . * : : :: ** : . *.*. * . .: . . : :::. : * . *:. . . . : : : . : . : * * . . : : .. : : : . :: * . * :::..: .: .: . *: . . * **** * *****:.:**:*:: .:* : **:**: **:*:****.*:***:* :*:*::::: * ", "identical_positions": 89, "similar_positions": 238, "identity": "8.21%" }, { "cls_id": "homologset.agr.MGI:1933158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VUW3-1", "uniprot_id": "Q9VUW3_DROME", "id": "Q9VUW3-1", "name": "Inositol-1-monophosphatase", "aln": "MSYRIGEEKLEVYYQVSLELVRKCGPLFLEGFQKPKTDYEVK-SAFYDLVTVYDKQIEATLTDGLLKTFPESKIIGEEAMANA-KTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYSAWQGHGAYLNGQPIEVSNA-KKINQALVCYEISLIVVSKGRD------KNVKRLYKLASS-ATGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGARFDVMKPDCVCTSSEELAKSVIQLIEGADQISGYTFK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUW2-1", "uniprot_id": "Q9VUW2_DROME", "id": "Q9VUW2-1", "name": "Inositol-1-monophosphatase", "aln": "MSSAVSESKLKEYYDVALKLVLKCGPLMQEGYQKAKTEYKVK-ADFYDLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVS-QRQAELTDAPTWIIDPIDGTTNFIHRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGEPIHTSKV-TTIKQAVIAYEISLIHAAGVRD------KNVKRLYKMASN-ATGTRCFGSAALTLCYVATGQCDAYHVEDLKPWDIAAGAIILTEAGGTVCHTSGSKFDVMKPDCVCAATPELAKNVISLIEEAGQITEYTFK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUW1-1", "uniprot_id": "Q9VUW1_DROME", "id": "Q9VUW1-1", "name": "Inositol-1-monophosphatase", "aln": "-MA-ASKSQIEELYDFIYPLAVRAGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFIGEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLYTAKLGQGAFCNGKPIQVSSC-EHLNDANVAYEVCLLHAPKIRN------KHIKRIYHVGSN-ARRLLAYSAVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGGPFDIMKPDLICAGTETLRAEIEHLIRKADQEKHVGGE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUW4-1", "uniprot_id": "Q9VUW4_DROME", "id": "Q9VUW4-1", "name": "Inositol-1-monophosphatase", "aln": "-MAGVSQADIEELYNFIHPLAIKAGEILMEGYEMASKNVSIK-GDFYDVVTDYDNKIEDFLMEKILARYPDHKFIGEEETAKNNNVSGELTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQKKLFTTKLGQGAFCNGKPIHVSSC-ESVKDANVAYEVSLLHVHSVAN------KHIKRIYHVGLN-ARRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFDIMKPDLICAGTEKLRKEIEDLLRKGDQEESVGGKPVQK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97697-1", "uniprot_id": "IMPA1_RAT", "id": "P97697-1", "name": "Inositol monophosphatase 1", "aln": "---MAD--PWQECMDYAVILARQAGEMIREALKN-KMDVMIK-SSPADLVTVTDQKVEKMLMSSIKEKYPYHSFIGEES-VASGE-KTVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCVEDKMYTGRKGKGAFCNGQKLRVSQQ-EDITKSLLVTELGSSRKPETLR------IVLSNMERLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRIIAASNIALAERIAKEL-EIIPLQRDDES----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55023-1", "uniprot_id": "IMPA1_MOUSE", "id": "O55023-1", "name": "Inositol monophosphatase 1", "aln": "---MAD--PWQECMDYAVILARQAGEMIREALKN-EMDVMIK-SSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGEES-VAAGE-KTVFTESPTWFIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQ-EDITKSLLVTELGSSRKPETLR------IVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRIIAANSITLAKRIAKEI-EIIPLQRDDES----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29218-1", "uniprot_id": "IMPA1_HUMAN", "id": "P29218-1", "name": "Inositol monophosphatase 1", "aln": "---MAD--PWQECMDYAVTLARQAGEVVCEAIKN-EMNVMLK-SSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEES-VAAGE-KSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQ-EDITKSLLVTELGSSRTPETVR------MVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEI-QVIPLQRDDED----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTW5-1", "uniprot_id": "Q7KTW5_DROME", "id": "Q7KTW5-1", "name": "Inositol-1-monophosphatase", "aln": "---MSHNVDVEKCLEVASNLVSEAGRLIARNNEQ-RQDFVCK-SNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGEEE-SSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTARRGHGAFYNGRRIHVSGQ-KELGKALVTSEFGTTRDEAKMK------VVHENFEKMAKK-AHGLRVLGSAALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEISKVLTQFNPLPRDD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05533-1", "uniprot_id": "INM2_YEAST", "id": "Q05533-1", "name": "Inositol monophosphatase 2", "aln": "-MVLTRQVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDK-ANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKG---VTKITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * :. * . ::** *:.:* : . : :* :**** :*: **:::**:*** *::: *. . *:*: .*:: . : : *:**: *.. :..* : .: : * ..: . .. :. :* * ** . ** ... :: **** : . ::: : ", "identical_positions": 41, "similar_positions": 66, "identity": "13.76%" }, { "cls_id": "homologset.agr.MGI:1933159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET26-1", "uniprot_id": "RN114_MOUSE", "id": "Q9ET26-1", "name": "E3 ubiquitin-protein ligase RNF114", "aln": "MAAAQPESRDGAAQSAKPASETDPLSRFTCPVCLEVFEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESIETSCHGCRKNFILSKIRAHVTSCSKYQNYIMEGVKATTKDASLQPRNIPNRYTFPCPYCPEKNFDQEGLVEHCKLTHSTDTKSVVCPICASMPWGDPSYRSANFMEHIQRRHRFSYDTFVDYDVDEDDMINQVLQRSIIDQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6J2U6-1", "uniprot_id": "RN114_RAT", "id": "Q6J2U6-1", "name": "E3 ubiquitin-protein ligase RNF114", "aln": "MAAAQPESRDGAAQSAKPASETDPLSRFTCPVCLEVFEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAAELERQIESIETSCHGCRKDFVLSKIRAHVASCSKYQSYIMEGVKATTKDASLQQRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLTHSTDTKSVVCPICASMPWGDPSYRSANFMEHIQRRHRFSYDTFVDYDVDEDDMINQVLQRSIIDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y508-1", "uniprot_id": "RN114_HUMAN", "id": "Q9Y508-1", "name": "E3 ubiquitin-protein ligase RNF114", "aln": "MAAQQRDCG-GAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCSKYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * :. **** * **:*:***.**********:*****************************************.******** *********:*.*****:**::*****.********* ****** **:*************************** *********************.****** *********************:**:***********", "identical_positions": 201, "similar_positions": 17, "identity": "87.77%" }, { "cls_id": "homologset.agr.MGI:1933161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGX0-1", "uniprot_id": "TRI23_MOUSE", "id": "Q8BGX0-1", "name": "E3 ubiquitin-protein ligase TRIM23", "aln": "MAALAVNKPGAGVDSGRQGSRGTAV--VKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGHIGQYGAAEEAIGTSGESIIRCDEDEAHVASVYCTVCATHLCSDCSQVTHSTKTLAKHRRVPLADKPHEKTMCCQHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSQVSTACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36407-1", "uniprot_id": "TRI23_RAT", "id": "P36407-1", "name": "E3 ubiquitin-protein ligase TRIM23", "aln": "MAALAVNKPGAGVDSGRQGSRGTAV--VKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGHIGQYGAAEEALGISGESIIRCDEDEAHVASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCCQHQVHAIEFVCLEEACQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSQVSTACLHCK-TLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVYHGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36406-1", "uniprot_id": "TRI23_HUMAN", "id": "P36406-1", "name": "E3 ubiquitin-protein ligase TRIM23", "aln": "MATLVVNKLGAGVDSGRQGSRGTAV--VKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4Q5-1", "uniprot_id": "F1Q4Q5_DANRE", "id": "F1Q4Q5-1", "name": "E3 ubiquitin-protein ligase TRIM23", "aln": "MAAAVGVNKQASMESCVRHGRGTAANAVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAVRCPFDRQVTELGDSGVWGLKKNFALLELLERLQNGATNQSGMSEDALREMGECIIRCDEDETHTASMYCTVCATHLCAECSQLTHSTRTLAKHRRVPLADKPHEKMLCPQHQVHAIEFVCLEDGCQPGPLMCCVCKEYGKHQGHKHAVLEAEANQIRASILDMAHCIRTFTEEVSEYSRKLVGIVQQIEGGEQIVEDSMGIAHTEHVPGTAESARSCVRAYFADLHETLCRQEEMALSVVDAHVRERLIWLRQQQEDMTILLSQVSTACLHCEKTLQQDDCRVVLAKQEINRLLETLQKQQQQFTELADHIQLDAGIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVIDSCHRDRLMESHSELAKLLTEKELRDALLLIFANKQDVPGAVSVEEMTELLSLHKLCCGRSWHIQGCDARSGMGLHEGLDWLSRQLVAAGVLDVA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . : *.::* : .****. ********************************************:*********:************************* .* * :*::: **.********:* **:**********::***:****:***************** :* *************:.**..******************:***.**********************:*:**********:**********.:*:***********.****:**** ***********************:****************:**:*****: ****************.***************:********.***********: *******************************************************************************:**.****: *:***************************.**:****:***************:************:*******************", "identical_positions": 497, "similar_positions": 55, "identity": "86.28%" }, { "cls_id": "homologset.agr.MGI:1933162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYR4-1", "uniprot_id": "A0A0G2JYR4_RAT", "id": "A0A0G2JYR4-1", "name": "Lipopolysaccharide-responsive and beige-like anchor protein", "aln": "MASEDNRAPSRPPTGDDGGGEGKEETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEAESITCMVELLEKCDITCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDSMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDKGQWPPHAGKLLSVLKHMPQKYAPDAFFNFPGKSAAAIALPPIARWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFVGGCLIITSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQMTAVYLFSDALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLLYDGKLSSAIAFTYNARATDAQLCLESSPKDNPSIFVHSPHALMLQDVKAVLTHSIQSAMHSVGGVQVLFPLFAQLDYRQYLSDEV--DLTICTTLLAFIMELLKNSVAMQEQMLACKGFLVIGYSLEKSSKSHVSRAVLELCLAFSKYLSNLQNG------------MPLLKQLCDHVLLNPAVWIHTPAKVQLMLYTYLSTEFIGTVNIYNTVRRVGTVLLIMHTLKYYYWAVNPQDRSGITPKGLDGPRPNQKEILSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMAEHPNSMTPAFDQRNGLRVIYKLLASKSEGIRVQALKALGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTMYNVLFEILIEQICTQVIHKQHPDPDSTVKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKSSDEQKITEMVYAIFRILLYHAVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREEQGKGDEEIGPCSASLSPEGTGVT----------------------------------------------------RDVDVSEGPQHSDRKESLISPHFTTNS-----------------------------------------------------------------------------------------------DENSSIGKASSIDSASNIELQTPGY---EKKVEQ---GNQELLDQ-----------------------------AAMEEATTNEAKHACDLEASS--DAVEPVTLTSTSSEP-GKDTVTISGVRASVSSPSEQDAAEMPELLEN-------------------------------SGVEEEDGDDDYVELKVEGIE---GSPAEEARLPAERQAEEARLPAEHQAEEACQPAERQGESVSVAASEGREEVE----------VCGNG--CELQEEAPITKSHNDPETGDSK------------ESGFPTVATAGSLATSS-------------EVPVPQTTLQ---PDSDEMLGGGVK-TDIAGETESVSDCADDVSEAP----------ATSEQK--------------IAKLDVSSVASDTER----------------------------FELKASTSTEAPQPQRHGLEISRQQEHPRQETAPDTGDQQRRDSRPT-----------MFRIPEFKWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDNVIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENVEPAQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKNMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKARGEA--AKSLKAVHSLVPVGRSA-AKSPVDIVTGGISPVRDLDRL-LQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEP----QDERHSQSLKEAGSDNGTVSLPD---------------AENTTAEFSSLTLSSVEESLEGTSSTRRRDSGLGEETASGLGSSMSVASPAAPLGVSTGPDAISEVLCTLSLEVNKSQETKNDGGNELDGKVTPS---VPVSKNVNVKDILRSLVNMPADG-VTVDPALLPPACLG----ALGDLSVDPPVQFRSFDRSVIIATKKS--------------SVLPSTLTASAPSNAVSVVSSVDSTQVPDAGGESPGS---------RSPNAKLP-SVPAVGSVP--QDPVTHMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREEEKMCDHLIRAAKYRDHVTATQLIQKVINLLRDKHGAWGSCAVS----------RPREFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEH-----------AADEDILAKGKQSIKSQALGNQNSENEALLEGDDDTLSSVDEKDLEN-LAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDSATVKKVVNYLPRVGVGTSFGLPQTRRISLATPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPSNFRDLSKPIGALNPKRAAFFAERFESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSVSRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVSLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQAYLLLQSPLMFTDQAQQDVIMVLKFPSNSPVTHVAANTQPGLAVPAVITVTANRLFAVNKWHS------LPAHQG-AVQDQPYQLPVEIDPLIACG------TGTHRRQVTDLLDQSIQVHSQCFVITSDNRHILVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKSSGIGDNPGSETTTPRAILTGHDYEITCAVVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGCFCTFSVNGKLQATVETDDHIRAIQLSRDGQYLLTGGDNGVVIVRQVSDLKQLFAYPGCDAGIRAMALSFDQRCIISGMASGSIVLFYNDFNRWHHEYQTRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESE1-1", "uniprot_id": "LRBA_MOUSE", "id": "Q9ESE1-1", "name": "Lipopolysaccharide-responsive and beige-like anchor protein", "aln": "MASEDNRAPSRPPTGDDGGGGGKEETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGESIMCMVELLEKCDVTCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDSMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDKGQWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIARWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFVGGCLIITSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQMTAVYLFSDALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLLYDGKLSSAIAFMYNPRATDAQLCLESSPKDNPSIFVHSPHALMLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYKQYLSDEV--DLTICTTLLAFIMELLKNSIAMQEQMLACKGFLVIGYSLEKSSKSHVSRAVLELCLAFSKYLSNLQNG------------MPLLKQLCDHILLNPAVWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVNPQDRSGITPKGLDGPRPNQKEILSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMAEHPNSMIPAFDQRNGLRVIYKLLASKSEGIRVQALKALGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTMYNVLFEILIEQICTQVIHKQHPDPDSTVKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYHAVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREEQRKGDEETGPCSSSLVPEGTGAT----------------------------------------------------RGVDVSVGSQHEDRKDSPISPHFTRNS-----------------------------------------------------------------------------------------------DENSSIGRASSIDSASNTELQTHDMSSDEKKVER---ENQELLDQ-----------------------------ATVEETATNGAKD--DLETSS--DAAEPVTINSNSLEP-GKDTVTISEVSASISSPSEEDAAEMPELLEK-------------------------------SGVEEKE-DDDYVELKVE------GSPTEEAGLPTELQ----------------------GEGLSVAASGGREEPD----------MCGHG--CEVQVEAPITKIHNDPETTDSE------------DSRFPTVATAGSLATSS-------------EVPVPQATVQ---SDSHEMLDGGMKATNLAGETESVSDCADNVSEAP----------ATSEQK--------------ITKLDVSSVASDTER----------------------------FELKASTSTEAPQPQRHGLEISRQQEQTAQGTAPDAVDQQRRDSRST-----------MFRIPEFKWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDNVIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKNMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKARGDT--AKSSKTIHSLIPMGKSA-AKSPVDIVTGGISSVRDLDRLPARTWTLIGLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEP----QDERHSQSLKETSSDNGNASLPD---------------AENTPAEFSSLTLSSVEESLEGTSCTRRRDSGLGEETASGLGSGLSVASPAAPLGVSAGPDAISEVLCTLSLEVNKSQETRIDGGNELDRKVTPS---VPVSKNVNVKDILRSLVNMPADG-VTVDPALLPPACLG----ALGDLSVDPPMQFRSFDRSVIIATKKS--------------SVLPSALTTSAPSSAVSVVSSVDPTHASDTGGESPGS---------RSPKCKTALSCKQLAPSH--KTPAAHMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREEEKMCDHLIRAAKYRDHVTATQLIQKIINLLTDKHGAWGSSAVS----------RPREFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEH-----------AADEDILAKGKQSIKSQALGNQNSENEALLEGDDDTLSSVDEKDLEN-LAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLATPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPSNFRDLSKPIGALNPKRAAFFAERFESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSVSRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQA-----SPLMFTDQAQQDVIMVLKFPSNSPVTHVAANTQPGLAMPAVITVTANRLFAVNKWHN------LPAHQG-AVQDQPYQLPVEIDPLIACG------TGTHRRQVTDLLDQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKSSGIGDNPGGETATPRAILTGHDYEITCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGCFCTFSVNGKLQATVETDDHIRAIQLSRDGQYLLTGGDNGVVIVRQVSDLKQLFAYPGCDAGIRAMALSFDQRCIISGMASGSIVLFYNDFNRWHHEYQTRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50851-1", "uniprot_id": "LRBA_HUMAN", "id": "P50851-1", "name": "Lipopolysaccharide-responsive and beige-like anchor protein", "aln": "MASEDNRVPSPPPTGDDGGGGGREETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGESINCMVDLLEKCDITCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDNMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDKGRWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIAKWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFVGGCLIVTSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQMTAVYLFSEALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLLYDGKLSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSPHALMLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYRQYLSDEI--DLTICSTLLAFIMELLKNSIAMQEQMLACKGFLVIGYSLEKSSKSHVSRAVLELCLAFSKYLSNLQNG------------MPLLKQLCDHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVNPQDRSGITPKGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMSEHPNSMIPAFDQRNGLRVIYKLLASKSEGIRVQALKAMGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTTYNVLFEILIEQIGTQVIHKQHPDPDSSVKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYHAVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIR----------------------------------------------------RDINVSVGSQQPDTKDSPVCPHFTTNG-----------------------------------------------------------------------------------------------NENSSIEKTSSLESASNIELQTTNTSYEEMKAEQ---ENQELPDE-----------------------------GTLEETLTNETRNADDLEVSS--DIIEAVAISSNSFITTGKDSMTVSEVTASISSPSEEDASEMPEFLDK-------------------------------SIVEEEE-DDDYVELKVE------GSPTEEANLPTELQ----------------------DNSLSPAASEAGEKLD----------MFGNDDKLIFQEGKPVTEKQTDTETQDSK------------DSGIQTMTASGSSAMSP-------------ETTVSQIAVE---SDLGQMLEEGKKATNLTRETKLINDCHGSVSEA------------SSEQK--------------IAKLDVSNVATDTER----------------------------LELKASPNVEAPQPHRHVLEISRQHEQPGQGIAPDAVNGQRRDSRST-----------VFRIPEFNWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDNVIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKTRGD----KALKPMHSLIPLGKSA-AKSPVDIVTGGISPVRDLDRL-LQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEP----QNERHSQSCTETGSENENVSLS-----------------EITPAAFSTLTTASVEES-ESTSSARRRDSGIGEETATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPS---VSVSKNVNVKDILRSLVNIPADG-VTVDPALLPPACLG----ALGDLSVEQPVQFRSFDRSVIVAAKKS--------------AVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGS---------RSSNAKLP-SVPTVDSVS--QDPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREDEKMCDHLIRAAKYRDHVTATQLIQKIINILTDKHGAWGNSAVS----------RPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHVCIFKLRENSKATDEDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEKDLEN-LAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLASPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQV-----SPLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHN------LPAHQG-AVQDQPYQLPVEIDPLIASN------TGMHRRQITDLLDQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKCSGIGDNPGSETAAPRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGLFCTFSVNGKLQATMETDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCIISGMASGSIVLFYNDFNRWHHEYQTRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AI36-1", "uniprot_id": "A0A8M3AI36_DANRE", "id": "A0A8M3AI36-1", "name": "Neurobeachin", "aln": "MASAGDSAVQ----------------------------IPIRGIRMKFAVLAGLLEAGEVSNRDTVETIFNLLVGGQFDLEMNFIIQETESIICMVELLDKCDSTCQAEVWNMFTAVLKKSLRNLQACTDIGLIQLVLQRIDRAETMIADLMVDMLGVLASYSITVKELKLYFSKLKGEQGQWPPHAVKLLSVLKSMAQRNGPDSFFSFPGKSAAAIALPPIAKWPYQNGFTFHTWLRLDPINNINVDKDKPYLYCFRTNKGLGYSAHFVGGCLIVTSLKSKAKGFQHCVKYDFKPQKWYMVTIVHIYNRWKNSEISCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQMGAVYLFSEALSAAQILAIYQLGPGYKGTFKHKAESDLLFAEHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLYDGKLSACIAFTYNPRATDAQLCLESSPKDNASIFVHSPHALMLQDVKAVVTHSVQSAIHSIGGVQVLFPLFAQLDFLQHSGDEL--DTSVCCTLLSFVMELLKGSVAMQEQVLACKGFLVIGYSLEKSSKVHVTRPVLDIVLAFARYLSNLPTG------------VMLLKQLCDHILFNPTIWIHAPAKVQLVLYTYLATEFISTVTIYNAIRRVGTVLQVMHTLKYFYWVVNPLDRSGITPKGLDGPRPNQKEIHSLRAFLLLFVKQLIMKDHGIKEDELQSILNYLLTMHEDDNLMDVLQLLVALMSEHPGSMVQAFDQRNGIRVIFKLLASTSEGIRVQALKVLGYFLKYLSPKRKSEVMLAHGLFSLLTERLMLHSNQFTVTTYNVLFEILTEQICTQVIHKQHPDPDSTVKIQNPQILKVIAALLKNAPPEAESMEVRRIFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCFINPKNSEEQKITEMVYAIFRILLYHAIKYEWGGWRVWVDTLSITHSKVTFEQHKENLARMFLEYQRIGSEGGSESRIRTISGVSQDS----------------------------------------------------QFLASANGELHTEEKAPSTVIELRVEE-----------------------------------------------------------------------------------------------QDNDQTADNEEMQTQIPVTVSNILVRDEEERLTDTVPTSVEMQDRDK-----------------------DEQYAVKEPEKDNEIKHMDDNHKTGDEDREQMENVKTEGRVEEESSNLSIKDDTDSPQTETDKNAKDATEAVKM-------------------------------SDEGKTSNAENEQNVQVEDEKKDLGDSTLEAVKEDSTQKSSEVLVHEETSTTGASVVNEDSTDVSSASNFVKVSDDSTEDSSFVSATTGETDDHGVEREDGGKEKENKSETDKDEKLMENEKTVGIQDSPAPMVEVDLNQSSSP-------------EETKPQTEGHG-DVEAEQTTTEQKSKAEVSSSAESISQDAANNQDSPKVAGTDNSANKTKEIK--------------IARLDVSSVASDTER----------------------------LELKDTSATNP------------SANQAAPTSPTGQSNEGSSSARST-----------MFRIPEFKWSHMHQRLLTDLLFSIETDVQMWRSHSTKTVMDFVNSSENVVFVHNTVHLISQVVDNLIMACGGILPLLSAATSSSHELENIEPSQGLAVEASLMFLQRLINLVDVLIFASSLNFTEIEAEKNMSSGGILRQCLRLVCAMAVRNCLECQQHTLSKSGAE-----SSRGQQSLLGAAKSIPAQSPVDIVTGGMSPIRDLDRL-LQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEP----HNDRR-----------------------------------NTQRSQSVRSTESVQSDLENGLSPLHRDSGIEDEKASDIQSNVKAQT---------GPDAVSEALSTLSDEVRRGQEDRDSKG-----------------KNVNVKDILRSLVSAPSDD-IMVDPSLIPPGFLG----AVSEASRDQSIQFHSFDRSVVVAPKKAGGAPSPGMSTVSASASVPSATAASSGGTPVNSVSVVSAGETVQSTESTPGG---------TSTSSNLP-SVPALSPMT--QTSTPNMSISERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSHTMKDHLVRVANEAEFILSRQRAEDIQKHAEFESHCAQYSAEKRDEEKMCDHLIRAAKYRDHVTSTQLIQKIVNILTDKHGAWGSSAFS----------RPREFWRLDYWEDDLRRRRRFIRNPFGSTHSEATLKAAAEH-----------APEEDVLK-GKQSIRSSVLGNQNSESELLLE-DDDTLSSLEEKELEN-LTGPVNLSTSAQLVAPAVVVKGTLSITALELYFEVDEEDPSFKNIDPKILAYTEGLHGKWLFTEIRAVFSRRYLLQNTALEVFMANRTAVMFNFPDAATVKKVVHCLPRVGVGTNVGLPQTRRISLASPKQLYKASNMTQRWQRREISNFEYLMFLNTISGRTFNDLNQYPVFPWVITNYDSEELDLTLPSNYRDLSKPIGALNPKRAAFFSERFESWEDEQVPKFHYGTHYSTSSFTQMWLLRIEPFTTFFLNFQGGKFDHADRTFSSVSRAWRNCQRDTSDVKELIPEFYYLPEMFVNSNNYNLGVMDDGTVVSDVELPPWAKSPEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAIRALNVFYYLTYEGAVNLSSISDPMLREAVESQIRSFGQTPCQLLIEPHPPRSSAMQVYLLLQTPLMFTEQMQQDVIMVLKFPSNSPVTHVAANTQSGLTNAAVITVTANRLFAVNKWHG------LTGHQTSSVQDQQYQLPVEIDPLIASN------VGAHRRQISDLLDQSIQVNAQCFVITADNRFILLCGFWDKSFRVYSTDTGKLTQIVFGHLDVVTCLARSESYIGGDCYVLSGSRDATLLLWYWNGKHSSIGESAGTEFVTPRAILTGHDCEVTCASVCAELGLVISGCREGPCLVHSMNGDLLRTLEGPDGCMRPRLVLSSTEGHCVIYYDKGHFCVFSINGKLLGHMEVEDNIKAMLLSKDGQYLLCGGDAGVLNVWQIHDLKQLFTYPGCDAGIRSMAIAHDQRCIITGMASGSIVLFYNDFNRWHHEYQTRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4E2-5", "uniprot_id": "NBEA_DROME", "id": "Q9W4E2-5", "name": "Neurobeachin", "aln": "MADIMRPPYSEIKRPDE-------------------IVRMTTADNLKFAVLIGLIEVGQVTNREVVNTVLHLLVGGEFDMELNFVIQDAQNIKHMLELLDHCPPNLQAEIWSVFIAILRKSVRNLQACTDVGLIEHVLVRLQRSETVVADLLIEMLGVLASYSITVKELKLLFGTMKATNGKWPRHSAKLLNVLRQMPHRNGPDVFFSFPGRKGSAMVLPPLAKWPYENGFTFTTWFRLDPINSVNIEREKPYLYCFKTSKGVGYTAHFVGNCLVLTSMKVKGKGFQHCVKYEFQPRKWYMIAIVYIYNRWTKSEIKCLVNGQLASSTEMAWFVSTNDPFDKCYIGATPELDEERVFCGQMSAIYLFSEALTTQQICAMHRLGPGYKSQFRFDNECYLNLPDNHKRVSHFQLLPATLGASALSGGSGSGTGSGTGNDASAAAAAAVAAGQQQQLQLQFQILAAEQEARAIDWSDEKLDLNAAFVKIRAVLTARNAVTLAGSSSTGTTAVATAAAAAAAAGAGAGTTAAATSAAAAAAATQNENDAAVGQQQHATHHHATAATGSADDPLGHLPTGNASSSSSSFEQLRRMSSVSSLNSMVGSADTEEVNQLKAVLYDGKLSNAIVFMYNPVATDGQLCLQSSPKGNVSYFVHTPHALMLQDVKAVVTHSIHCTLNSIGGIQVLFPLFSQLDMAHEGLGDIKRDPTLCSKLLGFICELVETSQTVQQHMIQNRGFLVISFMLQRSSREHLTLEVLGSFLNLTKYLVTCLSANSDLLLKQLFCFSFLTWQLLDHVLFNPALWIYTPANVQARLYSYLATEFLSDTQIYSNVRRVSTVLQTVHTLKYYYWVVNPRAKSGIIPKGLDGPRPAQKDILAIRAYILLFLKQLIMIGNGVKEDELQSILNYLTTMHEDENLHDVLQMLISLMSEHPSSMVPAFDVKHGVRSIFKLLAAESQLIRLQALKLLGFFLSRSTHKRKYDVMSPHNLYTLLAERLLLYEESLSLPTYNVLYEIMTEHISQQILYTRHPEPESHYRLENPMILKVVATLIRQSKQTESLIDVKKLFLQDMTLLCNSNRENRRTVLQMSVWQEWLIAMAYIHPKSSEEQKISDMVYSLFRMLLHHAIKHEYGGWRVWVDTLAIVHSKVSYEEFKLQFAQMYEHYERQRTDNITDPALRQARPISTISGWEREELHQQQNGGSAAAVATNQTAAVKGSVSIASLEDVPPVVEEEVEELELEEVEIQEGPITEETEQKSVIANISDVYNEQLKTDATCNGNLEDVKEEEPVQQQIGDLEKQPEPSTPLGALRETLQLGDDMDVEELELATAKDALNAEQHVSRVLQASEAALNDCKMAVDDVLQESSSVLKDEEIELAVNEVVQGVLNNEKKTQSQDNKDNKEQPGEQDVNVSLLNSKNLLNNNNNNNNNSPSPTPTTATATAETEAETEVNANEIVSSTEAPKAETETSVAPEVETPETAKPSPIVPSPVLATNQKTEDAANKLNNNEKLAEISASPEPPIVVETPEADLLQLSDSETKPNKETEAEDSVALAVRDIVEQLIDKVIDATEAESASETKTETNNNEIPKKEKQ-TSEEPEDVETAETLAAAAKEIVQEVVEAALVMVQEESTQEKPEKGANSEEEKNEIGKEEILLQLEEKPASTEVQETKIEGDLKKPEDPKGHSSVEPKTPNLEEPKPQETEQQKSQEVAEELPQKPEEQVVAIVNQVLDTLVDDTVKAVAAEQTTQTSPAPEEQSPQILAMESPATSVRVKPTEVDSTTQTTPKNEAGSSLLVEQVQQVLQEDDAQQSAGMTIEDEDYSNQQAAAAVENANSSQLDANHYGPGNPESKQQQQRSKSGSTRPMFSPGPTRPPFRIPEFKWSYIHQRLLSDVLFSLETDIQVWRSHSTKSVLDFVNSSENAIFVVNTVHLISQLADNLIIACGGLLPLLASATSPNSELDVLEPTQGMPLEVAVSFLQRLVNMADVLIFATSLNFGELEAEKNMSSGGILRQCLRLVCTCAVRNCLECKERTRYNVGALARDVPGAAHLQALIRGAQAS-PKNIVESITGQLSPVKDPEKL-LQDMDVNRLRAVIYRDVEETKQAQFLSLAIVYFISVLMVSKYRDILEPPAEPQIQRQSPVLQRTAGGGGRQIQDSDYEIIVVDENNPSVLADNDSHSSGPPSIKANQTTTIATTTTTTATTHINNNNTKTTTSNAPTATIKIQQQPLSPPKPLVPQKLPKSVDSDVGSLNMNSTENEVPEVESSSEILIDDHKPSHSNDESWTDVNLNEDAAVQAASAGIVVGLVDNRGNVISDKHDPSHHNQQQQQQAGIIGQQQQ-------------HGSLGHSERGDKPDSEISVVRVPDGYGGAGSGGGVNSGQGQGVPSNQRPRPEELPMKAPALVAQLPLTTPSREASLTQKLEIALGPVCPLLREIMVDFAPFLSKTLVGSHGQELLMEGKGLTTFKNSHSVVELVMLLCSQEWQNSLQKHAGLAFIELINEGRLLSHAMKDHIVRVANEAEFILNRMRADDVLKHADFESQCAQTLLERREEERMCDHLITAARRRDNVIASRLLEKVRNIMCNRHGAWGDSSSTSSGGAIVGAVQKSPYWKLDAWEDDARRRKRMVQNPRGSSHPQATLKAALEN----------GGPEDAILQTRDEFHTQIAVSRTHPSGQHNGELLDDAELLIEDRELDLDLTGPVNISTKARLIAPGLVAPGTVSITSTEMFFEVDEEHPEFQKIDGEVLKYCDHLHGKWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVKKVIKALPRVGVGIKYGIPQTRRASMMSPRQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWDSDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNCQRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKSPEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHL-----SPMMFS-AMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSNCFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIVFGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGE--GDVPTPRATLTGHEQAVTSVVISAELGLVVSGSSNGPVLIHTTFGDLLRSLDPPAEFHSPELITMSREGFIVINYDKGNVAAYTINGKKLRHETHNDNLQCMLLSRDGEYLMTAGDRGIVEVWRTFNLAPLYAFPACNAGIRSLALTHDQKYLLAGLSTGSIIVFHIDFNRWHHEYQQRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . . .:***** **:*.*:*:**: *:*:::*****:**:*:**:**: :.* *::**::* . ***:*.:* *:*:**:****.**::**:: ** :::: :.::***:::********.:**:**** *..::. :*:** *: ***.**: *.:: .** **.***:..:*:.***:*:***:***** **:*:**:*.:*::::*******:*.**:**:*****.**::**:* *.********::*:*:****::**:*****.:**: * ***:*** *::***.*.*.****::*:: * :******* *:****:**.: ** *:::** ***. *:.. *. * :.::** :******* .*.* **. ***.****:****.* * ***:************:***::.:::*:**:*******:*** : .:: * ::* .**.*: **:: * ::*:::: :*****.: *::**: *:: ** * :::** . .. * ** **:*:**::**::**:** **:**:***:. . **. :***.*** :*****:**.*** :*** ********* **:: ::**::*:*:***:* . *:******:***** *****:** ****:*::**:***.** *** ::*:* *:****: *: **:**** :*:**. : *** :** *.*::**:***:* : :::. ****:**: *:* *:::.:**:*:* :::** ****:*:*:::: . ::*:: **.** * *..*****::** ******::::.:::**.*:****::***::**:**:**:*:*:**********:*.****::* .* ::*.:: . : : : . : * : : .: ::... ..:: :. : : . : :. . : . . . : : .: . .. . . * :::.: : .: :. : : :: : *. . . :* . . .:. * . : . : .. . . * ..: : : . . .. * . .* . : : . :: : :. . .: ..* . : :*...: * : :* : . :. . :: . . : .: .* ******:** :*****:*:***:***:*:*******:*:******:*.:** **:*****: **:::****:****::***.. **: :**:**:.:*.:: *****:.:.******:**.* *:****.***************: ********:::: : . . ::*: .:: .:. *: :** :*.::* ::* : : ****::**:*::******:**:****************** : :*: . : : : . : : ::.:. * . . *..: . * : . . * : :* : *. * : . .: : . :. .:.: : :. ::: ::. :: . : . . :. * . .. . : . . : . . . *::::** ** ..******:********:**:********:**..*. :*.* *****************:**:********:*******::****:***********.* **:*: :**:*** *** ::*::*:****** **: **:* :::*::*: *:: ::*****..: : : :*:** **** ***:*:::** **:*.:****:* *: ..:: :* .: . .:.. :...: * **: :::::*: *:***.:** *:*:**.:*. **:*:*: *::******.*.*::** ::* * : ***** *:*:*::*********.***:*:*.*.:::* *** *****:: ******* . *:***** *: :*:** : *****:**:***************:**::*******:****:***:*::***:**:*:************.* *:* **:***:.: :* *********::*. **:*:***** ** :******:.** ***:* :*:*.******:******:*:***** * ..*.** :**::*.*:*******:.****:***:***********************:****:** **********:*.*..: **::***** ***.*****.***:******.***: :*:**: :*: :*** .**** *::*** . *: .:*:****.: ****:*: . : *. : *: ***::* . **:: * :.* :::.::*** * *.*.:: *****:****::*:*.:: *:**** .****:****. * .:**: *** *.*:***:**.: ..* . : :*** ****: :*.. :.******:**. :** *:*: *****:*: * *.*: * **. ** *::* ...:::*** :*:::.: **:**:**: .** *:: * : :* *:::*.*:****::*::.**: :::*:::***::*: ********** **", "identical_positions": 1234, "similar_positions": 863, "identity": "35.07%" }, { "cls_id": "homologset.agr.MGI:1933163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQG6-1", "uniprot_id": "TRIM2_RAT", "id": "D3ZQG6-1", "name": "Tripartite motif-containing protein 2", "aln": "MASEGASIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCER-CLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLMDVLQRTPGSNGEDPSILQTVTAVAAGKPLSCPNH---------------------------------------------------------------DGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVN--KRLPEIDSALQFISEIIHQLTNQKA--------SIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQS-----------------------------------------------------------------------------------------------QLDTLLQGQESIKSCSNFTAQALNHG-----------------TETEVLLVKKQMSEKLNELADQDFPLH-------------------------------------PRENDQLDFIVETEGLK----------------------------------------------------------------------------------------------------------------------------------------------KSIHNLGTILTTNAVASET-----------VATGEGLRQTIIGQPMSVTITTKDKDGELCKTG------------------------------------------NAYLTAELSTPDGSVA-DGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGS-----------------------------------PFKLKVIRSADVSPTTEGV---------------------------------------KRRVKSPGSGHVKQKAVKRPASMYSTG--------------------------------------------------------------------------KRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGS-----GKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSSNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYIN---TSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESN6-1", "uniprot_id": "TRIM2_MOUSE", "id": "Q9ESN6-1", "name": "Tripartite motif-containing protein 2", "aln": "MASEGASIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCER-CLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLMDVLQRTPGSNGEDSSILETVTAVAAGKPLSCPNH---------------------------------------------------------------DGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVN--KRLPEIDSALQFISEIIHQLTNQKA--------SIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQS-----------------------------------------------------------------------------------------------QLDTLLQGQESIKSCSNFTAQALNHG-----------------TETEVLLVKKQMSEKLNELADQDFPLH-------------------------------------PRENDQLDFIVETEGLK----------------------------------------------------------------------------------------------------------------------------------------------KSIHNLGTILTTNAVASET-----------VATGEGLRQTIIGQPMSVTITTKDKDGELCKTG------------------------------------------NAYLTAELSTPDGSVA-DGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGS-----------------------------------PFKLKVIRSADVSPTTEGV---------------------------------------KRRVKSPGSGHVKQKAVKRPASMYSTG--------------------------------------------------------------------------KRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGS-----GKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYIN---TSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C040-1", "uniprot_id": "TRIM2_HUMAN", "id": "Q9C040-1", "name": "Tripartite motif-containing protein 2", "aln": "MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCER-CLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNH---------------------------------------------------------------DGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVN--KRLPEIDSALQFISEIIHQLTNQKA--------SIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQS-----------------------------------------------------------------------------------------------QLDTLLQGQESIKSCSNFTAQALNHG-----------------TETEVLLVKKQMSEKLNELADQDFPLH-------------------------------------PRENDQLDFIVETEGLK----------------------------------------------------------------------------------------------------------------------------------------------KSIHNLGTILTTNAVASET-----------VATGEGLRQTIIGQPMSVTITTKDKDGELCKTG------------------------------------------NAYLTAELSTPDGSVA-DGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGS-----------------------------------PFKLKVIRSADVSPTTEGV---------------------------------------KRRVKSPGSGHVKQKAVKRPASMYSTG--------------------------------------------------------------------------KRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGS-----GKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYIN---TSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B666-1", "uniprot_id": "A0ACD6B666_DANRE", "id": "A0ACD6B666-1", "name": "Tripartite motif-containing protein 2", "aln": "MATDASTLPSPVVRQIDKQFLICSICLDRYNNPKVLPCLHTFCER-CLQNYIPPHSLTLSCPVCRQTSILPEKGVAALQSNFFIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLMEVLKKSPNSNLSED-YTDAINGVATGQPLSCPNH---------------------------------------------------------------GGNVMEFYCPPCETAMCEECTSGEHAEHATVPLKDVLEQHKASLQEQLDAVK--NRLPEIESALEVLSEILQQLSSQKS--------SIEEMIHATFEELQKTLNVRKSVLLMELEVNYGLKQKVLQT-----------------------------------------------------------------------------------------------QLESLLQGQDGIRSSCSFTEQALNHG-----------------SEAEVLLVKKQMSERLDELANQELPLR-------------------------------------PEENNQLDFLVETDGLR----------------------------------------------------------------------------------------------------------------------------------------------KSIHNLGAIVTTNAVAAET-----------VATGEGLRHCIVGQLTSVTVTTKDRDGGLCRTG------------------------------------------NALLIADLSAIDGSIVGEGKVTDHKNGTYEFVYSVPCEGRFTLTLKLYDQHIRGS-----------------------------------PFSIRANKPTDISLTADVD---------------------------------------KKRLKSPGNSHVKQRAIKRPASMYSTG--------------------------------------------------------------------------KRKENPIEDDLIFRIGTKGRNKGEFTNLQGVAASSVGKVLIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKSKIGS-----GKLMGPKGVSVDRNGHIIVVDNKSCCVFIFQPNGKLVSKFGNRGNSDKQFAGPHFAAVNQNNEVIVTDFHNHSVKVFSPEGEFILKFGSNGEGNGQFNAPTGVAVDANGNIIVADWGNSRIQVFDSSGSFLSYIN---TSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8A5M1-1", "uniprot_id": "B8A5M1_DANRE", "id": "B8A5M1-1", "name": "Tripartite motif-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAPQASPDSSSEECTVLEALP--GKGTALICSQH---------------------------------------------------------------KGKVSALYCLVCENAVCEDCMNGEHAEHPTDSLEKAVDQQLAALQDKVDSAK--NRLPQIREAVQYLREILQQLNSQRS--------SIEEDIHSSFSELHKTLDTRKSVLLMELEVTYGLKQKVLQA-----------------------------------------------------------------------------------------------QLDTLLQEESAINYNCSLTSEALDGG-----------------SKASVLQAHKEAGERLGDLSSQGLPLQ-------------------------------------PEENDQLDLMMEIEGLR----------------------------------------------------------------------------------------------------------------------------------------------KSIHNLGTIVTTNAVASQT-----------EASGDGLEQCIVGQPASVIITTRDKAGGLCKTG------------------------------------------NAIISAEVYTPDGSIA-DGEIVDMKNGTYEFQYTVKKEGNFSLALRLYDQHIKGS-----------------------------------PFQLKVSSSPDDSPTTTTAANAASTGSSDGG-------------------------ARKRSAKSPGS-RSRQKGVRRGGSLFSTP--------------------------------------------------------------------------KKRVNPIEDDLIFRIGTKGRNKGEFTNLQGVAACSEGRILIADSNNQCVQIFSNTGEFQSRFGVRGRSPGQLQRPTGVAVHPNGDIIIADYDNKWVSIFSSEGKYKAKLGS-----GRLMGPKGVSVDQNGHVIVVDNKACTVFIFQPSGKLITKFGSRGNGDRQFAGPHFAAVNNNNEIIITDFHNHSVKVFNADGEFLLKFGSNGEGNGQFNAPTGVAVDVNGNIIVADWGNSRIQVFDGSGSFLSYIN---TAADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZK8-1", "uniprot_id": "B7YZK8_DROME", "id": "B7YZK8-1", "name": "", "aln": "-------------MEQFEQLLTCCVCLDRYRIPKLLPCQHSFCMEPCMEGLVDYVRRQVKCPECRAEHRIPYNGVQAFPTNVTLQRFLELHIEITGELPDPTSGQIMERCGVCSEKAYLSHCAHCEKKICEDCKSAHMDILRREITRFNSQIRRSLHRLQDSLAIIEKNTMSLQTNAISVTEEIDEIYQRITKAIKDRSDQLKGEIDRYLAVELRNLTTLKENLDLEITNITSNCDTVDKYMNETVEWDDCELMDTKEIFLKTVEFLRHFEYENNDYSRRVRFLVSIDPNQLVMNLATFGDLNIAPHSTPSGGSVSSSHLAPPSALQPGLMRSKSDHRLATQFRQQEERSGYNDEPVLGGRKFGERPQRSATQANNDRYGRSGGDYDYENDYDNEGSSGRAGKSSRFRSRFVRSHQNDDSDSEQQQQQRQQELKERKDRVLDSEDVSRGQLSGIIRLSDCSRVVQRLADIGKEKKEKKSDAAAAAQAAVQAAIQAQKAAMQRQQQKNQQNAADEEELARQKRKNAGSSSTGGAATSTSSGGGDTASDQRVAALKNRGGEESDGSSNQAASPVRNSAASTTRAEVSVNEANTEEEGVASESSDSEEDEEVEDEDEEEEVDEEEEQVEESVEEEEAPRELLNLPEEALQPTSSEVTEEEESSSEYEEVTATESEEEQEEVEGRVIEIESQDLPVINVLPPENDIAHKVEESPVDHISNQELMEETDKSTDESPEEEEEEEYTEEEIESKPPVSAQVAAVKKTQRSGSSDSSASTESSASSAAAAAVAATSTSATAAAPATSSSNSTSQNAKAPSSSRYSTARDTTAVPEKKPFVSRFLPQHSTASTTNGSADKKKAESSSSSEEETSSESESESEPETKAKSSATSSTTNTKSTPNSAASSTTAASSSTTSGSYRDRLEARRASRDDSSSTAAGRSSYATPSSSGYGSGSGTTGGRTRAVPAPHHTSESEDRYGSGTGSSYTSRFLNKSKSSAIVTQPSLSTPTASFDEDATGTGDDSDSRYGTGRSRYLAMKERRTRLARSRSSHQFGNDDEDLDEPVSPTTVSPSAYLASRCAYSGYGSSDLSRSRSSHALKSRDNSPITDRGAGSSRSSGLGGSSTTDSKDGEALSSWARYLKNKYGNKSSKDSAGSSGSARDTHAGSSTSSSAAASSSHAHGYGSGTSGSSGRSTASDVSRRLSLGLPLRQANELASSDDDGSKNGLGSPTSPTVAAAVAAAGITGAAGTIPKQVYLRKRQQLFQLGGRGSEPGSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAVNRIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGTADGKFNYPWGVTTDALGFIYVCDKENHRVQVFQSDGSFVGKFGSCGRGEGQLEHPHYIAVSNTNRVIVSDSNNHRIQIFDVNGKVLSTVGGEGSDDGQFKFPRGVAVDDQGYIFVADSGNNRIQIFNPDGSFLKTFGSWGSGDSEFKGLEGVAIMSNGNILVCDRENHRVQVF----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :*... . . * .:* *: : . .. :. . :: :: *:. :: : : . . . **.: .:: : :* :: ..::: :: *:: ::: : .:. * *: :::. .: *:: :: :.. . .:. :**: : :. ::: :: :: .* :*: *.*::: : * : ** * .: ** * :: * *: :. *: . :: . . ** :. : : : * . . *. * : ** . * . * *: .::: .. . . :. . * * : * *.*. : : . .* :: :: : : :*::* :* : *.** :*:*. . . :::***.*: **:*.. * * ..** *.. *::: :****: *: **** *: :.::. :*:: :** *:: * **:.* *.: * *:: * :**..*.:: :**. *..: *: **: **...*.:*::* :** :::*. :*:.: ..*.:*..:***: * ***** :* *:*** **.***:*: .****. :. :. . : * :*:*: *:*:::*.* ** .:*: ", "identical_positions": 141, "similar_positions": 252, "identity": "9.19%" }, { "cls_id": "homologset.agr.MGI:1933169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES21-1", "uniprot_id": "SAC1_RAT", "id": "Q9ES21-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "----MAATAYEHLKLHITPEKFYVEACDDGADDVLIIDRVS--TEVTLAVKKDVPPSAVTRPIYGIMGTIHLVAGNYLVVITKKMKVGEFFNHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLSTDGFYFSTTYDLTHTLQRLSNTSPEFQEMS-LLERADQRFVWNGHLLREL----SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSG------NRASFVQTRGSIPVFWSQRPNLKYKPDPQINKVANHMDGFQRHFDSQVIIYGKQVIINLVNHKGSEKPLEQTFAKMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEM---QDELSYFLVDSAG---KVVTNQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDE-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLVMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDELDS---HSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--VASIGTFFIILYNGKDFVDAPRLVQKEKID-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP69-1", "uniprot_id": "SAC1_MOUSE", "id": "Q9EP69-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "----MAAAAYEHLKLHITPEKFYVEACDDGADDVLIIDRVS--TEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLVVITKKMKVGECFNHAVWRATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLSMDGFYFSTTYDLTHTLQRLSNTSPEFQEMS-LLERADQRFVWNGHLLREL----SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSG------NRASFVQTRGSIPIFWSQRPNLKYKPHPQISKVANHMDGFQRHFDSQVIIYGKQVIINLVNHKGSEKPLEQTFANMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEM---QDELSYFLVDSAG---KVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDE-FEKTYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLLMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDELES---HSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--VASIGTFFIILYNGKDFVDAPRLVQKEKID-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTJ5-1", "uniprot_id": "SAC1_HUMAN", "id": "Q9NTJ5-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "----MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVS--TEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMS-LLERADQRFVWNGHLLREL----SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNG------SKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEM---QDELSYFLVDSAG---QVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDE-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELES---HSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--VASIGTFFIILYNGKDFVDAPRLVQKEKID-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L244-1", "uniprot_id": "SAC1B_DANRE", "id": "A1L244-1", "name": "Phosphatidylinositol-3-phosphatase SAC1-B", "aln": "-----MASTYNSFNLHTTAEKFYIEACDDGVGDVLAIDRVS--TEKTLTVRKDVPPSAVTRPICGIMGTIRLVAGVYLIVITKKKKVGDLLGHAVWKASDFDIISYKKTVLHLTDNQMQDNKVFLSMLNSVLNTDGFYFATDYDLTHTLQRLSNTSPEFQEMT-LLERADQRFVWNGHLLREF----MAQPELHRFVFPVIHGFIAMRSCCINGKIFDWNLISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIIQYNG------AKASFIQTRGSIPFYWSQRPNLKYKPKPQISKSINHLDGFQRHFDSQIIIYGKQVILNLVNQKGSEKPLEQAFAKMVGSLGNGMIKYIAFDFHKECSRMRWHRLQILVDTVAEL---QDEFGYFLVDSDG---SVQMQQDGTFRSNCMDCLDRTNVVQSLLARRSLQSQLERMAVLHVGQRIEEQAD-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYAVEEADM---NTPLHEPKDWKFLTLPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--SASVVTGGVILFNGRDFVDAPRLVQKEKMD-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4VCH0-1", "uniprot_id": "SAC1A_DANRE", "id": "A4VCH0-1", "name": "Phosphatidylinositol-3-phosphatase SAC1-A", "aln": "-----MANAYERFNLHSTPEKFYIEACDDGADDVLVIDRVS--TEMTLAGIKDIPPSGITRPICGVMGTVRLVAGMYLIVITRKRKVGDLFGHTVWKAVEFDVISYKKTILHLTDIQMQDNKTFLTMINNVLNTDGFYFCTDYDLTHTQQRLSNTSPDFQEMS-LLERADQRFMWNGNLLREI----IAQPELHKFAFPVIHGFIVMKPCCINGKVFEWIIISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVQFNN------ARASFVQTRGSIPFFWSQRPNLKYKPKPLISKDTNHMDGLRRHFESQVLIYGKQVILNLVNQKGSELPLEQAFAKMVSSMENGFIKYIAFDFHKECSKMRWHRLQILVDAVSDM---QEEFGYFMVSSDG---KVLSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQSQLQRMGVLHVGQKIEEQAD-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHWGLVMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDETDS---LTPLHVKKDWKFLLLPVIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--MASALTAAVIVVNGREFVDAPKLVQKEKMD-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0I6-1", "uniprot_id": "SAC1_DROME", "id": "Q9W0I6-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "MDSREENAVYDDMNLYIAPQSFIIEP--NGGDELLVIGRHDKVTRVQPASGGLVANLRPTRRICGVLGTIHLLSCDYLLVATHRLFVGVLNGAVVWRLAGYDIIPYIP-----NSFQRKENENYLRLLRQTLDTKFFYFSYRYDLTNSLQRQREVAQSRPEVSGLLQRAEQRFVWNGYVLRQF----NCD-KMEKFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVETEQIVEFNG------QLTGFVQTRGSMPFHWHQLPNLRYKPRPVLVPGKDHLAACGLHFKEQIRLYGNNVAVNLVDHKGAEGELEATYARLVREMGNPQVRYESFDFHSECRKMRWDRLNILIDRLAHE---QDQFGVYHVFDDG---KLVSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHASDIFESIFKGVWADNADLVSLQYSGTCALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNFADGQRQDSIDLFLGKYLVNDNEGGAVPSPLESKHGWRFFTFPSVLLVAVAMFMITMTYPAEFNTENLLFMLFWG--AMIAVSATGILHYGVEFVQWPRLFPPISFRDP-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32368-1", "uniprot_id": "SAC1_YEAST", "id": "P32368-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "--------MTGPIVYVQNADGIFFKLAEGKGTNDAVIHLANQDQGVRVLGAEEFPVQGEVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFN-----SRIDSEEAEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAASWKT-----ADERFFWNHYLTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPN--LVLGENSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAP-LLTSYQNLWADNADAVSVAYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRPHTASIK---SPFPDRRPVYIQLIPMIICAALTVLGATIFFPKDRFTSSKNLLYFAGASIVLALSTKFMFKNGIQFVNWPKLVDVGFLVVHQTHDKEQQFKGLKYAQSPKFSKPDPLKRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : .: . : * . .. . * .::* ::* * :: . .* . ..:: ..::. . .:: :: ::. *. . ***. ****:: ** :.. : *::**.** : .:: : .:. * *:: *: :*. : :*:*** ***.* : ** *.:*:..** *****: .. .*:*****:*..* : **:*** : : : . **..* :**.: :**:::** * :: : :* : . ::* **** ** .*:*.*:.:*:* : . :::: : . * .: * ...*:**:********:**:**: * :: *: .*. *. : . ::. *****: : *:** *************: * . * ** *** **::** **** ***** : . . :*: : : :* :: .*.:: : . : *.. : * * : :. * :**: *:*. : ", "identical_positions": 153, "similar_positions": 177, "identity": "23.65%" }, { "cls_id": "homologset.agr.MGI:1933172", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76LD0-1", "uniprot_id": "CRDL1_RAT", "id": "Q76LD0-1", "name": "Chordin-like protein 1", "aln": "------MEGIKYIASLVFFFVFLEASKTEPVKHSETYCMFQDKKYRVGEKWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPTLHCLSPVHIPHLCCPRCPDSLPPMNSKVTSKSCEYNGTTYQHGELFIAEGLFQNRQPNQCSQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDADIFRQPANREARHSYLRSPYDPPPSRQAGGLPRFAGSRSHRGAVIDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKLDGKCCKVCP----EEPPSQNFDSKGSFCGEETMPVYEAVLVEDGETARKVALETEKPPQVEVHVWTIRKGILQHFHIEKISKEMFGGLHHFKLVTRTTMNQWKIFAEGEAQLSQMCSSRVCRTELEDLVQVLYLERPEKDHC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920C1-1", "uniprot_id": "CRDL1_MOUSE", "id": "Q920C1-1", "name": "Chordin-like protein 1", "aln": "------MDGMKYIISLFFIFVFLEGSKTEQVKHSDTYCVFQDKKYRVGEKWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPSLHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFIAEGLFQNRQPNQCSQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDAELSWEHADGDIFRQPANREARHSYLRSPYDPPPNRQAGGLPRFPGSRSHRGAVIDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCP----EEPPSQNFDSKGSFCGEETMPVYESVFMEDGETTRKVALETERPPQVEVHVWTIQKGILQHFHIEKISKRMFGELHHFKLVTRTTLNQWKLFTEGEAQLSQMCSSQVCRTELEDLVQVLYLGRPEKDHC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BU40-6", "uniprot_id": "CRDL1_HUMAN", "id": "Q9BU40-6", "name": "Chordin-like protein 1", "aln": "MRKKWKMGGMKYIFSLLF-FLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:*** **.* *::**..*** ****:***:**********:********************************.:**********************:*.********************:*************:**************************************.******:*.*************** ** *****.******.**.*:******::*****************************************************************************:********* :* *.*.**.** ***********:*::*****:**:*****:***********:**************.** * *********:.***:*:*****:******:**********:**** *.**.**", "identical_positions": 389, "similar_positions": 46, "identity": "85.12%" }, { "cls_id": "homologset.agr.MGI:1933174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPK1-1", "uniprot_id": "BRI3_RAT", "id": "Q5PPK1-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDY----ACGPHGYGAIPTAPPPPP-YPYLVTGIPTSHPRVYNIHSRAVTRYPANSIVVVGGCPVCRVGVLEYCFTCLGIFLAIVLFPFGFLCCFALRKRRCPNCGAVFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28662-1", "uniprot_id": "BRI3_MOUSE", "id": "P28662-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDY----ACGPHGYGAIPTAPPPPP-YPYLVTGIPTSHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEYCFTCLGIFLAIVLFPFGFLCCFALRKRRCPNCGAVFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95415-1", "uniprot_id": "BRI3_HUMAN", "id": "O95415-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDY----ACGPHGYGAIPAAPPPPP-YPYLVTGIPTHHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEDCFTFLGIFLAIILFPFGFICCFALRKRRCPNCGATFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAC9-1", "uniprot_id": "E7FAC9_DANRE", "id": "E7FAC9-1", "name": "Membrane protein BRI3", "aln": "MDTKPLLQDRPPAYNTVPSAYDYGSIPAAGAPAAGFQPPAPPPYQGFPAAASGYPAAPAPAAAQPAFSTYTIVQPSVVVVGGCPACRVGVLEDDFTCLGIMCAIFFFPLGILFCLALRQRRCPNCGATFG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZP9-1", "uniprot_id": "Q9VZP9_DROME", "id": "Q9VZP9-1", "name": "Membrane protein BRI3", "aln": "-MADTRKDAAPPSYEEVMNSPSQDSRLIVGVHQG--APSAPPPNMHMPTYGAFETTPVSVVIQPAPVAMP----TEIIVIGGCPACRIGYLEDTFSACGLCCAIFFFPLGILCCLAMREKRCSNCGTVF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : **:*: . . * *.**** * : .: . . . : .::*:****.**:* ** *: *: **.:**:*:: *:*:*::**.***:.* ", "identical_positions": 36, "similar_positions": 35, "identity": "27.69%" }, { "cls_id": "homologset.agr.MGI:1933176", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85967-1", "uniprot_id": "GSDMC_RAT", "id": "P85967-1", "name": "Gasdermin-C", "aln": "MLYTFDQVSKDVVKKLQGKDLRPVRCLSDATKFRQFDILQKTP---QSLFFKSEDTPVGYSLLQILEPNFPVPETEVSAPMPLKHITSQKWKADVDVKATIADGGASAEFVQSCGYDIEVQSRSIPDSKLESLQNRQGPWGKLLDKKLSFVTDCQMGRNNLYVVTEVFEVTKDTVVQGSSSIDLSGK-ALVSQLVKGEAQGQWQRETTDLVPIPKGAVLAYKKKQLVIENNTCAILLSANAKKKTFP---------------------------GIFNFGMS--SRSQTMEIVNSSWID---------YIPPIGRIEEPVHLDFKYLEKEVFLRKEQLAMLSKDVQDVVFSNLLPMLSDSDVLFDLINMLELDQLGHMDGPAGLILDELRKNSSTPWIDLKGLILYLLQALMVLSDTQLDLLAQSMEMRILLQQRELVRSILEPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLKGCGLKMEPNSPRSTWDLEAKMPLSALYGILSCLQQLVEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NB5-1", "uniprot_id": "GSDMC_MOUSE", "id": "Q99NB5-1", "name": "Gasdermin-C", "aln": "MSYTFDWLSKDVVKKLQGRDLRPVKCLSDATKFCLFNILQETS---SRLALKTEYIPVGFTLLHLLEPNIPVPEPEVSAPIPLKHTISQKLKADLDVET-IAGG--EAGFVKSCGYDIEVQSKSIPNPKLESLQNR-----KLLDQLPTFMKTCWKDGKNLYVVTEAYEVTKDTVLEGTSNSKFAIK-GIINQLVKVGGSGQWQTEKTDSIPIQKGSVLAYKKQQLVIEDNTCVILTSANTKKKMTF---------------------------PMRFVGMSGHLRYQDLVIETGSWIN---------DIDPIGTIKEPTHLDFMCLQNEVSEQTRLLAELSKDVQEVVFSSFLHMLCDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSLSWINLKDLILYLLQALMVLSDTQLCLLALSVEMRLLPHQVELVKSILQPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLSEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYG8-1", "uniprot_id": "GSDMC_HUMAN", "id": "Q9BYG8-1", "name": "Gasdermin-C", "aln": "MPSMLERISKNLVKEIGSKDLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVEFSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVS-VSGEASVDHGCSLEFQIVTIPSPNLEDFQKR-----KLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEK--AILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSNDMKLKPELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLRDRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNPKDPILYLLEAIMVLSDFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGLLEECGLRMELDNPRSTWDVEAKMPLSALYGTLSLLQQLAEA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: :**::**:: .:** **: * .***: * **::. . : ::: ** ::* .:***. .* *. *:.*: :.. ** ***:.*:. * . .. . * .:*.* :**..:**.:*:* **** :*:. * .*******. *: ::**: .:*. .: * .: * ..*: ... :.: ** *:***::****::: .** * : ::: . * : : : . .::. * *:* *:** :* *::** : . ** ******:*:* .:* ** * ..* **::****:. **:***.* **.:*:::*. .*:: *. *****:*:***** * *** *:* *:* :* ***:***:***:***.*****:*:******.******* **: ***:** :.******:*********** ** **** **", "identical_positions": 202, "similar_positions": 142, "identity": "39.15%" }, { "cls_id": "homologset.agr.MGI:1933177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M784-1", "uniprot_id": "F1M784_RAT", "id": "F1M784-1", "name": "Phosphoinositide 3-kinase adapter protein 1", "aln": "------------------------------------------------------------------------------MAASGWGWGCDILIFYSPDAEEWCQYLQDLFVSCRQVRSQKIQTYRLVPDACFSSQDLSVFRDARCVLVLLSAGLVECFVQPGLLP---------------------------------------------------------------------------------------------------------------VLQRACHPPQRVVRLLCGVQPNDEDFQAFFPDWAHWQELTCDDEPETYLAAVRKAISE----DSGCDSVTDTEPE----------------------DERALPFSKHTDLPLETSPGNL---------------------------MVVQPDRIRCGAETTVYVIVRCKLDEKVSTEVEFSPEDSPSVRMEGTLENEYTVSVKAPDLSSGN---VSLKVYSGDLVVCETTISYYTDMEEIGNLLSSAANPVEFMCQAFKIVPYNTETLDKLLTESLKNNIPASGLHLFGINQLEEDDMMTNQRD-EELPTLLHFAAKYGLKNLTALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKSHIKEELMQGEEADDVYESMAHLSTDLLMKCSLNPGCDDELYESMAAFAPAATEDLYVEMLQASAG-------NPVSGESFSRPTKDSMIRKFLEGNSMKLASL-----------EREQHPP-HGEELYHTVEEDETFSVDLANRP-------PVPVPRPETSTPGPHPLPDNEPYISKVFAE----KSQERVGNFYVSSESIRKEP---LVRPWRD------RPPSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLR---DSITRRQREKQKSGKHADLEITVPIRHSQHLP-------GKVEFGVYESGPRKSVFPART--ELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEITRSRGPGPTQVDGAPVVTG--TPVGILERPPRVP-PRAASQ-----RPLTREPFHH--PPPPVPPRGR-------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ32-1", "uniprot_id": "BCAP_MOUSE", "id": "Q9EQ32-1", "name": "Phosphoinositide 3-kinase adapter protein 1", "aln": "------------------------------------------------------------------------------MAASGWGRGCDILIFYSPDAEEWCQYLQDLFVSCRQVRSQKTQTYRLVPDASFSAQDLWVFRDARCVLVLLSAGLVGCFGQPGLLP---------------------------------------------------------------------------------------------------------------MLQRACHPPQRVVRLLCGVQPGDEDFQAFFPDWAHWQEMTCDDEPETYLAAVRKAISE----DSGCDSVTDTEPE----------------------DERELPFSKQTNLPPEISPGNL---------------------------MVVQPDRIRCGAETTVYIIVRCKLDEKVSTEAEFSPEDSPSIRVEGTLENEYTVSVKAPDLSSGN---VSLKVYSGDLVVCETTVSYYTDMEEIGNLLSSAANPVEFMCQAFKIVPYNTETLDKLLTESLKNNIPASGLHLFGINQLEEDDMMTNQRD-EELPTLLHFAAKYGLKNLTALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKTHIKEELMQGEEADDVYESMAHLSTDLLMKCSLNPGCDDELYESMAAFAPAATEDLYVEMLQASAG-------NPVSGESFSRPTKDSMIRKFLEGNSVKPASW-----------EREQHHP-YGEELYHIVDEDETFSVDLANRP-------PVPVPRPEASAPGPPPPPDNEPYISKVFAE----KSQERLGNFYVSSESIRKEP---LVRPWRD------RPPSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLR---ESITRRRKEKPKSGKHTDLEITVPIRHSQHLP-------EKVEFGVYESGPRKSVLPART--ELRRGDWKTDSMSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEIPEITRSRGPGPTQVDGAPVVTG--TPVGTLERPPRVP-PRAASQ-----RPLTRESFH---PPPPVPPRGR-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUJ8-1", "uniprot_id": "BCAP_HUMAN", "id": "Q6ZUJ8-1", "name": "Phosphoinositide 3-kinase adapter protein 1", "aln": "------------------------------------------------------------------------------MAASGVPRGCDILIVYSPDAEEWCQYLQTLFLSSRQVRSQKILTHRLGPEASFSAEDLSLFLSTRCVVVLLSAELVQHFHKPALLP---------------------------------------------------------------------------------------------------------------LLQRAFHPPHRVVRLLCGVR-DSEEFLDFFPDWAHWQELTCDDEPETYVAAVKKAISE----DSGCDSVTDTEPE----------------------DEKVVSYSKQQNLPTVTSPGNL---------------------------MVVQPDRIRCGAETTVYVIVRCKLDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKAPNLSSGN---VSLKIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTETLDKLLTESLKNNIPASGLHLFGINQLEEEDMMTNQRD-EELPTLLHFAAKYGLKNLTALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKSHIKEELMHGEEADAVYESMAHLSTDLLMKCSLNPGCDEDLYESMAAFVPAATEDLYVEMLQASTS-------NPIPGDGFSRATKDSMIRKFLEGNSMGMTNL-----------ERDQCHLGQEEDVYHTVDDDEAFSVDLASRP-------PVPVPRPETTAPGAHQLPDNEPYIFKVFAE----KSQERPGNFYVSSESIRKGP---PVRPWRD------RPQSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLR---DSITRRQREKQKSGKQTDLEITVPIRHSQHLP-------AKVEFGVYESGPRKSVIPPRT--ELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMS--------LERPPRVP-PRAASQ-----RPPTRETFH---PPPPVPPRGR-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA54CYI8-1", "uniprot_id": "A0AA54CYI8_DANRE", "id": "A0AA54CYI8-1", "name": "", "aln": "--------------------------------------------------------------------------------------MCEVLIVHSGEAREWADYLQQILEASCSFQEGSVVLYDVDEEICLKN--YGPFGSSKCILLLLTSGLVNLQNDSVVLD---------------------------------------------------------------------------------------------------------------TFRDLLHPPHKVVAFLCGVS--EELMSGYFEYWEQWRKIFSEDEPQVYVSTIRESIDEGSVLQHQCQNTYEIEPEEP------------------LEDLPLPDFSEILPLPDELNEHQLNGDEVCSFLQTG------LNTSNDQICLSVQPDRILCGSGVSIFVMLVQKCEDEDSVEVEFHSQQSPPLRLPGTLVNQCIVTVQSPDMPAGE---VSLTVYKNQSVLCSSTVTYYTEMEEICRYLKKATDPVQFMCQAFDITSKLQESLDNLLATSLEERMPVNGLQVFGISQIEEN-TAANHRD-VELPTLLHFSAKYGLKKLTSLLMRCPGAMQAYSVMNKDGDYPNKLAEKSGFSDLRQFMDEYVETVDLVKTHIEESQN-APESEDIYEDMLRASQNFISEFDN-----ENIYESMVKLNPEMGDELESALEDSNPERMLRKFFEGPPEKGFQSMKHNSTNGGLPEMDDEDYHDMGVKVDVYGDFEEEDPYNPCCPEQIYDTVEPHS--SPEVMNRP-------PAPIPRP-AKLPEPE---ENTTYISKVFCP----KDP-----LYSVSQRPERDPSIAPVRLVRD------RDMSSHHDPFAGMKTPGQRQLISLQERVKVGELTVEEAVQEFKAWQFDQDKRWRSLRFQQENLHRLR---ESITRRCKDKGTN----ELMITAPMQTNTQWGS-----QMNVNCSVYEPTPRTVVQPPSVNRAPQRGSWQTGSTSSTSSSSSHRLSIQSTVSNSSGVDGEEEPPDIPLPPRPLRP---VVDSPPILPPPRVPPRVIERSPEILNERYVSNP---SRPVPQNPAQRPIPPPPVPRRTW-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFI0-1", "uniprot_id": "Q9VFI0_DROME", "id": "Q9VFI0-1", "name": "", "aln": "MFVTVDNTNTFFSDNPYYFCNETKSPRTPDSQSSSRGFSIFKRRNSKGSSPRPLVMTNPEQMRLITSANLDTTATMALGSPRGSFNSLAGYPQHAIELQTMNMYRQRSANSHSEFRERLNSCNETHSSQCPGGGGASVAGDHDEVFNPLTSPTSKSHRHHTLPSGGTRRHSLGNWAQHQHQQQHQQNSGAMGLGSPDEVPSMMAPRPPLLSPNKFRGSSHRRRDNCGNVNNTSGSSASGFLGSPGYNMDDILIITAKHSERAYLRATFLKNHFDKITKQRGRKPFNFLHIKIDDGPFSEEIAHKYQNTALQIVILCPALLALPHSFLMTQLSAIIRVEKVLAILLDVSEEKVKEMHKSALPSYYKWRRCVVRDNDQVQISNILGIATDILGRALCQRPPCQDSSGGGGGGLSRSFSSCTEGFTVLPKKVKLGQNK-VVALLAEPLEKNDTLKLQVEKSGELIELRNFKCRNPYTLQFNIPEACMEISTMIEIRIEKNNKSLGARPIKCESRLRELEQLLRIEDSPIEFMCHALGIGPVERDALDQHLLQCFQRNMPPNFHLLSGPSERQPHFFTRLESSPEEYPTLLHFAARWGLNRLCIQLMECPGGDTACGVRNCAGRTPAELAEQEGHHKLAQNIVSFAEFHELTTMYHYFKGVTPPGESCPKPSANVVIEAHPVKAGKTNKPPKELPTAEYMEMSSGSERENTPEVRTKTETLAISNLNYISVETEDENLQASVAEKKVESEKKLPEAGNQPG------PEKTTNELRINEPPYYQSKEQNQQPKELKNQSKSLDEVDAAPLYQTDKFSQECSQLLENQLGNDYVLQPSNVPVAQDDGNYLFQPSNRPVEEPLRLNRCTNRQPGYGTLKRSASDASAASHTRSNADDELAEIMHDFKNNVLSIRDVEVLVERWKHRN-DVQQSFREKQDQIDQLRREYERIQEQVKSHLKRETPFERIKKFFLRSKTPGGNDSLLDETKSSIATSCSFKSAGGVSSSAGAGRPISSLSLQSVSSSSSSSGRLSTGSNCSGASLGDSGTHSDHEDRRFPHCRMMDNYMVPPTPRPVFTPSSTPGDERHQIVFPSPMSSCQRLNTPTSPTGSEHYQMFPSNIPVYGSQPLVGSQSSNYLNTIMEAKEQAETQHYQNQNGVTLQPIKLNERSNIIYGKLTKSSSASGCSSFKPKQIPVPCPQVGSIEVQAEVYQNVGDVAPEKDSKAEEETPNYMNC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . * * : ..:. . . . :. *:: . : : : * ..: : . .* : : : . : : :. : : . * * *: :. * : * *.:: * : :: :.. : : :. . . . * : .: *: :.: : ..: : :. : :.*: . * .*::***:*: * . ::**: * .::..:* . : * .: : . . . * ******:*::**:.* *: ***. * .* * * * :**: *. .* * : .:.* :: . : . . . : . .:: : . : :.. : . . . : * * :. *. * * . .. . :: .:. ..*: :. :* *: :: *: . * *: : :* .. : :: .: :* : . .* . :.: :. .: *: : . .*:* :*:::.:** : * .: :.: . : . :: . : . .. . .. . .. . * **::**:.. : . . * * .* .. : .: * .* ** : * . . . : *. :* ", "identical_positions": 89, "similar_positions": 239, "identity": "7.25%" }, { "cls_id": "homologset.agr.MGI:1933179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXY2-1", "uniprot_id": "SRCN1_RAT", "id": "Q9QXY2-1", "name": "SRC kinase signaling inhibitor 1", "aln": "MQPWQCLRRFALAWWERTAEGRARSPREEVGPRDPGGRGEPDPERSSPPMLSADDAEYPREYRTLGGGGSGGSGGRRFSNVGLVHTSERRHTVIAAQSLEALSGLQKADADRKRDAFMDHLKSKYP-QHAL---------ALRGQQDR-MRE---------------------------------QQPNYWSFKTRSSRHTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELEDVR----DIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPASHLASSSPPPGLPSGLPSGLPSGSPSRSRLSYAGGRPPSYAG---------SPVHHAAERLGGAPTSQGVSPSPSAILERRDVKPDEDLAGKAGGMVLVKGEGLYADPYGLLHEGRLSLA-----AAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAG-AGGPLYGDGY-------GFRLPPSSPQKLADVSAPSGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKARSTG-ASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPE--------------TPSEKIEGS---------NGAATPSAPVCGSGSRSSGATPVSGPPPPAVSSTPAG-QPTAVSRLQMQMHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQ-RTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVAHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVK----FLKEEPQRLDGLLKRCRVVTDTLAQIRRQVDEGVWPPPNNLLNQSPKKVAAETDFSKGLDFEIPPPSPPLNLHELS--------GPAEGTPLTPKSGNP------------TKGLDAPSKRN-MDKAVSVEA---AERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKTHP-------GPTPTPDHKPPKAPHGQKAAPRTEPS------------GRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSS-HGLTTTRTGEVVVTSKKDSVFIKKAESEELEIQKPQVKLRRAVSEVVRPASTPPIMASAIKD---EDDEERIIAELES------------------------GGGSVPPMKVVTPGASRLKAAQGPAGSPDKGKHGKQ-----------RTEYM--------------------------------------------------RIQAQQQVR-VGYQAPRPLEGCTP--------RLCYMPLS---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWI6-1", "uniprot_id": "SRCN1_MOUSE", "id": "Q9QWI6-1", "name": "SRC kinase signaling inhibitor 1", "aln": "MQPWQCLRRFALAWWERTAEGRARSPREEVGPRDPGGRGEPDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVIAAQSLEALSGLQKADADRKRDAFMDHLKSKYP-QHAL---------ALRGQQDR-MREQVGGWTVDPVCLLSSLCSHLHGDSTPSGAGQPAQQPNYWSFKTRSSRHTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELEDVR----DIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPASHLASSSPPPGLPSGLPSGLPSGSPSRSRLSYAGGRPPSYAG---------SPVHHAAERLGGAPTGQGVSPSPSAILERRDVKPDEDLAGKAGGMVLVKGEGLYADPYGLLHEGRLSLA-----AAA-ETHSHTRARAACTSGVPCALSAPTPLPRCSPTWRTRCTRR-ALAALYGDGY-------GFRLPPSSPQKLADVSAPSGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKARSTGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPE--------------TPSEKVEGS---------NGAATPSAPVCGSGSKSSGATPVSGPPPPSASSTPAG-QPTAVSRLQMQLHLRGLQNSASDLRGQLQQLRNVQLQNQESVRALLKPTEADVSMRVSEAARRQEDPLQRQ-RTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVAHNHRLMPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVK----FLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGMWPPPNNLLNQSPKKVAAETDFSKGLDFEIPPPSPPLNLHELS--------GPAEGTPLTPKSTNP------------TKCLDASSKRN-TDKAVSVEA---AERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKTHP-------GPAPTPDHKPPKAPHGQKAAPRTEPS------------GRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSS-HGLTTTRTGEVVVTSKKDSVFIKKAESEELEVQKPQVKLRRAVSEVVRPASTPPIMASAIKD---EDDEERIIAELES------------------------GGSSVPPMKVVTPGASRLKAAQGPAGSPDKGKHGKQ-----------RTEYM--------------------------------------------------RIQAQQQATKPSKEVSGPNETSSPGSEKPSGSRTSIPVLTSFG-----ARNSSISF-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0H9-5", "uniprot_id": "SRCN1_HUMAN", "id": "Q9C0H9-5", "name": "SRC kinase signaling inhibitor 1", "aln": "-------------------MGNAPSQ---------------DPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVIAAQSLEALSGLQKADADRKRDAFMDHLKSKYP-QHAL---------ALRGQQDR-MRE----------------------------------QPNYWSFKTRSSRHTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELEDVR----DIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAG---------SPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLA-----AAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGY-------GFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPE--------------TPSEKIEGS---------NGAATPSAP-CGSGGRSSGATPVSGPPPPSASSTPAG-QPTAVSRLQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQ-RTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVK----FLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELS--------GPAEGASLTPKGGNP------------TKGLDTPGKRS-VDKAVSVEA---AERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHP-------GPAPTPDHKPPKAPHGQKAAPRTEPS------------GRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSS-HGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKD---EDDEDRIIAELES------------------------GGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQ-----------RAEYM--------------------------------------------------RIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFG-----ARNSSISF-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J2Z9-1", "uniprot_id": "A0AC58J2Z9_DANRE", "id": "A0AC58J2Z9-1", "name": "", "aln": "-------------------MGNAPSQANVG-----ACFPKQDPERGGGHMISTDDLEYPREYRTLG------NNTRRFSNVGLVHTSEHRHTVIAAQSLETLTNLHKADMERKRDVFMDHLKNKYPPQHSLPPSPSPSHGSMRGSAERSAREQ--------------------------------QQPNYWSFKSRSPRHSQSTQSGLADQASKLSFASAESLETMSEADMPLGFNRMNRFRQSLPLSRSASQNKLRSPGVLFLQFGDETRRVHITHELNSLETLHALIVHMFPQKLTAGMLKSPNTAILIKDEARNVFYELEDVR----DIQDRSIIKIYRKEPIYASYPAAHLANGDLRREMVYTSRDSSPTRRLNTLPSSSTSHS----------------SGSPSRSRLSYSGGRPPSFAGPGHPHPQGPQHSQHSHHPSPSHGQGQGLTPSSSAILERRDVKPDEEMSGKN--MVLLKNEGLYADPYSLMHEGRLSIASTQSLATIADPFGFPVSGGLYRRGSVRSLSTYSAAALQNDLEDSLYKPG---GSLYSDAYSSSTLGMGFRLPPSSPQKIPDVQLRD------RDSFTGSPSRGSPVRTTFRKDSASSSVFVESPKSRP------SSSSEPLGDGSKGAG------FGSPLSGGEIDSRDRMEAMEKQIASLTGLVQSVLTRAPDSDSTCGLLRLCMMAGCPPDQGADFSRPFPFSSSEKTESTSEGSATGTGRLKKKALTPSAPLALMPPPSSGGSQASTVSRLQMQLHLHDLQQNATDLRKQLAQLRKMQLQNQDSIRSLLKRTETELSLRLSDALRKQEDPLQRQ-RLLVEEERLKYLNEEELIIQQLHDLEKSVEEIQKEISVNHRHVTVQELEEKSSMLRKLGETLTELKNQFPGLQSKMRVVLRVEVEAVK----FLKEEPHRLDALLKRCKSITDTLTTLRRQVNEGVWKSQDEFSSPS-AKLGGGDEYRKNTDFDIP-TSPPLSLNESSLANWSPHPGQGHGHSNSSHAQREKDSHGVMVGSLKTRGLEELGGRGGSEKASSVEVRLAAERDWEEKRASLTQYSAQDINRLLEETQAELMKAIPDLDFAAKQIKPAQNQNQNQNQNPNQNQNPSPSSTNATPEHRPNKPQHKLNSKDSGSRRGSDELTVARYRTEKPSKSPPPPPPRRSFPSS-PGLTT-RSGEIIIPGKS----IKKSESEEAESQKPHVKLRRSISEAPRPASTPPTIAGGERE---EADDEKLAAELEQQLTPSKSGFHENSSDLTQKPMIQHGVSSNPVPQIVLTECGSLPMSPSEDSAENRPSSDDQTIKDNDTGNDIRVSYFSHIVRTPRLSLWKQDLTTSQKVPQIQDLDAAQRELQCPVHDVTQSCLPLTRERAIKQPLRREPRVQESLEAVTEAKDKPMRKSDTILSVSLQNGAAETPQNSLIRTQGVGGEKEDICHSTYRRLDSLEETIRELELSLMEFSTDPHMGNFFHPSAQMPSSSTERSGSIRQMAQSPSDGGGTARPIVPPKPSCISTSTAKTSGGKALSRLKHLQQSGSEKIKTSKQREDFLKNHGQQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KW14-1", "uniprot_id": "CCDCX_DROME", "id": "Q7KW14-1", "name": "Coiled-coil domain-containing protein CG32809", "aln": "------------------MLIRWKSK---------------DKSASSNQSVGGSSSSSSKKK-----------RKGREGEEDWQNEAKSGRLPSNEQGGDERRRAMRRDDPRRHTLGGDMLVYGSQHPHAH---------QMAPQQQR---------------------------------------AMDLEMSTRAQKNKKNQPMRGYAPVNQGPLFDDDPGIMSEVETASTGFRRGGKQRSSLPVVRTPSKTLERPLGLVFLQYRSETKRALLPNEITSIDTVRALFVRSFPRQLTMSYLEGPNVKIYIHDASKDMFYELEDVRSHLREIRDRSVLRLFESTEVAAPP---QILPGGPGIPQPLPQAQANWDQDQSYFSEPEFDSD----------------YKHQHIHKSKIGKQPAPYYVG-----------------SSQTLPRGMYSSERNKVSMDGYTSSPER------------SSRGNYEEPYYSQYGTRGAVV-------------APIIDEEQSDGTMTEDQYALYGIKVGPGPNRLTHRG------------------NQIYDPTRPEDLHRIRVEH-------MERQLANLTGLVQKALVNQNPQIAPLAVPTLDPNYLVVPSQMQANGSGDELYIREK-------APKLGKNSCQKSVSFEKSVSFSDDIQGIPKSHNPLHAAET--------------KPTKPAIKS--------------STLPRTSSQERDRLKPPPPPKPIVLAQTAHPNYRADIALAPEVYNHLRGLQKKAKDLRMEVRTLRRLSQAQAVAVREDIKGTFMRIRATLLASSGSFWDHQGDQDATRISREEELYKQEVIRLEKDLSDLEGSVENLRGEVINRRTRVNMTAVEDMALVLSRASKTVAELKLKFPSLSNGLRCILSNEMEKVVREEKFLKEEPDRLESALRRCKKLTGTLVTLKRLASVQEQRLPPNEPTISEETPRSADISAP----DKPIPTPRMGSFALSG-------GLAPENALDALLDELKTFSKPIAQQQQQQQQQQQQQQQQHQHQQLYEIRPEDSASDESAQAAVQSTVTTQISQARLYTEASVNVQQATTGSMVIAVAS------GTVSAQAQAQRGVLTHQQSQSQAQLMVHT---------NMGSLRRLHSYPSESDGELPGPPPTGPRASETSSSTSLANGGSSSKPPVPERNAELITKVGHKRIPPPPPPRTSSRSPLASPTSPNVPPNQAAAATVNLIPNSNSNASANANAN-----------------------ANSNATGNKGIVGETTSVVSGDTSSGDNSSGNESGNDHVQRQVALEMRHQELLK------------------------------------------------KQKMLQEQYQRLQQMSKLPSVDVASSSSSSAQDIASGSNTLRKLGSETNIQQKIAALSLACETSG----------------------------------AAAAAAAAAAAAATNGGVVASDATSGAIGGGGGAGAAGAAGASAAAAHSNSNSNSNLNLNLNSQHQTATTTTKQLYETEIL-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * . .. :. .. . .:: * .: . : :: : *. : : * *:: * * *: : . :* . .:.:*: ::.:. . : . . :. . . ** * .: *.***: *:.*:. *. *::***: .**:*. :.:*:.*::*::**:.: **::** . *:.**. * *:* ::::******** :*:***:::::.. : *. :: *. .. ::. : . :. . . : . . .* :.* . : .. :: .*:. ...* * :** : * ::. . * . . . *: *:.: : . * : ..::. :.: . : . :. . .: .. : . :. :* . .: *: :* . * : * . . .: . . . .: . :. . :: **:.**:.*.*** :: **.:. : ::* :* * : : : * * :..*. * :: : ::* *** ***::: :: .: : :*: : :* : .:*::*** :**.*.. :* :* *:* * ******.**:. *:**: :*.**. ::* .. : . * . . : * .:* :. * * . . . . : : : :: * . . *. :*:: . : :*.: *:*.: . . . : :: .. . . . .* .:: .***. ** * .** .*:. :.. : *.* :. * . *: ....** *.. .:.. *: : . .. . : : : . . . . . : * . : : : :: . . : ", "identical_positions": 157, "similar_positions": 347, "identity": "9.91%" }, { "cls_id": "homologset.agr.MGI:1933180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZC26-1", "uniprot_id": "D3ZC26_RAT", "id": "D3ZC26-1", "name": "Ferritin", "aln": "--------MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIZ8-1", "uniprot_id": "D3ZIZ8_RAT", "id": "D3ZIZ8-1", "name": "Ferritin", "aln": "--------MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K1G6-1", "uniprot_id": "A0A0G2K1G6_RAT", "id": "A0A0G2K1G6-1", "name": "Ferritin", "aln": "--------MAEAPSQVRQNYDWHCEDAVNTHIQLRLYASYVYMSMAVYFDRDDVALGNFKRFFLSKSHECQAKAEVFMHLQNTRGGCLSLHDIARPERDSWHGGSQAMECALHMEMMINQSLLNMHEVAKEKGDAQLCHFLEQNFLNQQVEVLKEVGGYLTNLRQMGAQEHSLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MX2-1", "uniprot_id": "FH17E_MOUSE", "id": "Q99MX2-1", "name": "Ferritin heavy polypeptide-like 17E", "aln": "--------MAEAPSRMQQNYDWQCEDAINTHIQLCLYASYEYMSMAVYFDRDDVAQENFKRFFLTKSHNCQTSAEMFMHLQNKRGGCSSLQGIARPERDSWHGGFQAMECAFHMEMLINQSLLNMHEVAKEKGDPHLCHFLEQNCLDQQVDILKEMSGYLTNLRQMGAVEHNLAEYLFDKLSLS-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7X4-1", "uniprot_id": "FHL19_HUMAN", "id": "P0C7X4-1", "name": "Putative ferritin heavy polypeptide-like 19", "aln": "--------------------------------------------MAFYFDQDDAALEHFDRYFLRQSQEKREHAQELMSLQNLRGGRICLHDIRKPEGQGWESGLKAMECTFHLEKNINQSLLELHQLARENGDPQLCDFLENDFLNQQAKTIKELGGYLSNLHKMGAPEAGLAEYLFNKLTLGRSQKHTRAQTGPTATGCLPLLAPPGGTSMFPFQNILFIFLLSVLPLLAIKLSVLKAIKVSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BXU8-1", "uniprot_id": "FHL17_HUMAN", "id": "Q9BXU8-1", "name": "Ferritin heavy polypeptide-like 17", "aln": "-------MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLSDDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQLAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRVKET-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYH1-1", "uniprot_id": "Q9VYH1_DROME", "id": "Q9VYH1-1", "name": "Ferritin", "aln": "MAWCFRDIRRHMCMLVRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMTYMNKRGGLIILSSVPQP-LPCFASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIEANFLQEQVDGQKILADYISQLEKAQN---QVGEFLFDKYMGSGMHPAK-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :*::.* : : *:** * : .: :: * *** * .: :* : . *:: ::::* :*: **::: :* : *.:**.*: . *.:*.. * :..*:::*.: :.*:**:* . ", "identical_positions": 33, "similar_positions": 52, "identity": "13.47%" }, { "cls_id": "homologset.agr.MGI:1933181", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYK8-1", "uniprot_id": "EIF3D_RAT", "id": "Q6AYK8-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDETSFQLVDTARTQKT-AYQRNRMRFAQRNLRRDKDRRNMVQFN---LQTLPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQ---KPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGRE--RYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSEEDEEDEEEEE---EEEEEEET--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70194-1", "uniprot_id": "EIF3D_MOUSE", "id": "O70194-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDETSFQLVDTARTQKT-AYQRNRMRFAQRNLRRDKDRRNMVQFN---LQTLPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQ---KPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGRE--RYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSEEDEEDEEEEE---EEEEEEET--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15371-1", "uniprot_id": "EIF3D_HUMAN", "id": "O15371-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDESSFQLVDTARTQKT-AYQRNRMRFAQRNLRRDKDRRNMLQFN---LQILPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQ---KPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGKE--RYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDEEEEEEEE---EEEEEEET--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TH15-1", "uniprot_id": "EIF3D_DANRE", "id": "Q6TH15-1", "name": "Eukaryotic translation initiation factor 3 subunit D", "aln": "----------MAKFHAPVIQDNPSGWGPCAVPEKFKDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDEASFQLVDTAKTQKT-AYQRNRMRFAQRNLRRDKDRRTLTQFN---MQTLPKSAKQKERDRMRLQKKFQKQFGVRQKWDQKSQAQLKPRDSSVEVRSDWEVKEEMDFPRLMKMRYMDVADPLDIECCGALEHYDKAFDRITTRNEKPLKSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMCCTRSVNSWDIIVQRVGNKLFFDKRDNSDFDLLTVSETANEPPQDEGSSLNSPRNLAMEATYINHNFSQQCLRMGGE--RYKFPNPNPFVEEDTEKSEVASVAYRYRRWKLGEDIDLIVRCEHDGVMTGANGEVSFINVKTLNEWDSRYCNGVDWRQKLDSQRGAVLATELKNNSYKLARWTCCAILAGSEYLKLGYVSRYHVKDSSRHVVLGTQQFKPNEFASQINLSMENAWGILRCVIDICRKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDEEEDDEDE---EDEEEDEDN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGC7-1", "uniprot_id": "EI3D2_DROME", "id": "Q9VGC7-1", "name": "Eukaryotic translation initiation factor 3 subunit D-2", "aln": "-------MSNYAPFIKPYVEYNEHGWGPCEVPE--LDVPYQPFCKSDRLGKICDWTAMVP-EKKFPSKYASTFGNNSQYAYFYEDDDSTFHLVDTTGSKATKPYQRGRYRPNMRNNVRSRGRTGRGTPNIASLGGSTAGGATASTTKYGKGRNTRNTQNMGRRFG-RNAPT-RIRESSVMVQSDWVSIEEIDFPRLLKLALPNIKDGKDIATCGWLEFYDKLYDRVNLRNEKPLQKMDRVVHTVTTTDDPVIRRLSRTMGNVFATDEILSTIMCCTRSNYSWDVVVEKLGTKVFLDKRYNDQFDLLTVNETSVEPPMDEEGSINSAHSLAMEATLINHNFSQQVLRIGDQEPRFMFEEPNPFE--EPGVD-LASIGYRYRQWDLGNDVVLIARCKHNGVIQGPNGDVQFLSIKALNEWDSKVTNSVEWRQKLDTQRGAVLASELRNNACKLARWTVEAVLAGSDQLKLGYVSRMNPRDHLRHVILGTQQFKPQEFATQINLNMDNAWGVLRCLIDLVMRQPDGKYLIMKDPNKPMIRLYDVPENAFDSDGDEEEESSD----PLSNSNDN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCK0-1", "uniprot_id": "EI3D1_DROME", "id": "Q9VCK0-1", "name": "Eukaryotic translation initiation factor 3 subunit D-1", "aln": "MSETINTAAQFPSFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTNTSNNDKKYQNKYASSFGTGIQYSYYHEEDETTFHLVDTARVQKP-PHQRGRFR-NMRNSRSGRGRNAR--------GGLNTHGMTTLSGKNVKARDPRHGRGMGKKFGHRGPPP-KMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGVDIVTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCSTRSNYSWDIVIEKVGDKVFMDKRDHTEFDLLTVNESSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEPKYKFEESNPFISEDEDIQ-VASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFMTIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDEGFQQVYNYAHNKI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :: * ***** :*: *:*****.*.*****:.*** :*:: .**:* ** . **:*::*:*:::*:****: : . .:**.* * ** .:.* . : :. :: .: :::. :. : *:*** *::** **:***:*:*: :: : ** ** **.*** :**:. :.****:.:.*:.************:*::* ******* **:*:*..*** ***::::::* *:*:*** : :******.*:: *** *: .* **.:.**:*** ******** *: * : :: * :.*** : . :**:.***::*.**.*: *:.**:*:**: ..*: .*:.:*:******: *.*:******:*****:*.**:**: ***:** *:****: ******** : :* ***:********:***:****.::****:***:**: : :*****:***** :**:*.:*:.:*.*: .:: : .: : . ", "identical_positions": 251, "similar_positions": 167, "identity": "43.88%" }, { "cls_id": "homologset.agr.MGI:1933184", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ86-1", "uniprot_id": "NOP58_RAT", "id": "Q9QZ86-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASATLSEFLSEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGAENRAKLEARLRILEDRGIRKISGTGKALAKAEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEEVDKEDEITEKKAKKAKIKIKAEVEEEM--EEAEEEQVVEEEPTVKKKKKKDKKKHIKEEPLSEEEPCTSTAVPSPEKKKKKKKKKDAED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DFW4-1", "uniprot_id": "NOP58_MOUSE", "id": "Q6DFW4-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASASLSEFLSEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQSSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGIENRAKLEARLRILEDRGIRKISGTGKALAKAEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEEVDKEDEITEKKAKKAKIKIKAEVEEEMEEEEAEEEQVVEEEPTVKKKKKKDKKKHIKEEPLSEEEPCTSTAVPSPEKKKKKKKKKDAED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2X3-1", "uniprot_id": "NOP58_HUMAN", "id": "Q9Y2X3-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVE-------EEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKRENED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM69-1", "uniprot_id": "Q9VM69_DROME", "id": "Q9VM69-1", "name": "Nucleolar protein 58", "aln": "-MFVLYETPAGYAIFKLLDEKKLEQVDNLYQEFETPEKANKLLKLKHFEKFNDTTEALAAATAAVEGKVAKPLKKTLKKLLVDDVQSSLLVADAKLGTAIKDK-LSVQCVCNTGVQELMRCIRQQADSLLGGLPKREMTAMALGLAHSLSRYKLKFSPDKIDTMIVQAQCLLDDLDKELNNYMMRAREWYGWHFPELGKIITDNIAFVKTIKLVGTRDNMATSDLSDILPEDVEEKVKEAAEISMGTEISEEDVLNIQCLCDEIISINDYRTHLYDYLKARMMAMAPNLTVLVGDTVGARLIAHAGSLINLAKHPSSTVQILGAEKALFRALKTKKDTPKYGLIYHAQLVGQASQKNKGKMSRSLAAKASLATRVDAFGEE--ATFELGAAHKVKLESRLRLLEEGNLRKLSGTGKAKAKFEKYQAKSEVFTYQPEADNTLN-VKKKRKHSESEQQTPVKKE-------------------EPAEEEAEVKSE---KKKKKKKKQKDEEVEAVEEAAAPEPEDQPTPAKKKKKSKHQE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12499-1", "uniprot_id": "NOP58_YEAST", "id": "Q12499-1", "name": "Nucleolar protein 58", "aln": "MAYVLTETSAGYALLKASD-KKIYKSSSLIQDLDSSDKVLKEFKIAAFSKFNSAANALEEANSIIEGKVSSQLEKLLEE-IKKDKKSTLIVSETKLANAINKLGLNFNVVSDAVTLDIYRAIKEYLPELLPGMSDNDLSKMSLGLAHSIGRHKLKFSADKVDVMIIQAIALLDDLDKELNTYAMRCKEWYGWHFPELAKIVTDSVAYARIILTMGIRSKASETDLSEILPEEIEERVKTAAEVSMGTEITQTDLDNINALAEQIVEFAAYREQLSNYLSARMKAIAPNLTQLVGELVGARLIAHSGSLISLAKSPASTIQILGAEKALFRALKTKHDTPKYGLLYHASLVGQATGKNKGKIARVLAAKAAVSLRYDALAEDRDDSGDIGLESRAKVENRLSQLEGRDLRTTPKVVREAKKVEMTEAR----AYNADAD-----TAKAASDSESDSDDEEEEKK------------------EKKEKKRKRDDDEDSKDSKKAKKEKKDKKEKKEKKEKKEKKEKKEKKEKKSKKEKKEKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **..***::* : **: : ..* :::::.:*. * .*: *.**:.:::** .: :***: . *:* *:: : .: :..* *:::**. .*:. *... : .. . :: * *:. *: *: .::: *.******:.*::****.**:*.**:** .**********.* **.:**********.**::*.::: : : :* *.: : : **::*.*::* .** ***:*****::: *: ** *. :::.: ** :* :**. ** *:***:* :**: ********:***:.*** .:**:**************:::*******:***.****:: *:***::* ****: :: * **:.*: : :* :.*:* ** ** .:*. . . : * * : : :*:...* * . .: :.: :: * *:: ..: *..** *:*. : * .: :**.*.:::: ", "identical_positions": 196, "similar_positions": 181, "identity": "36.23%" }, { "cls_id": "homologset.agr.MGI:1933185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70303-1", "uniprot_id": "PYRG2_MOUSE", "id": "P70303-1", "name": "CTP synthase 2", "aln": "-------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCS-------SNLLFKWKAMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGICLGMQLAVIEFARNCLNLKDANSTEFEPN----TPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTEN--SILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIVELTSHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAHLQQMNKLPY---SDGYSDASDDSF----PEAKLAELDLN----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2N0-1", "uniprot_id": "PYRG2_RAT", "id": "Q5U2N0-1", "name": "CTP synthase 2", "aln": "-------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQDWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKRENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLDLPINDCS-------NNLLFKWKTMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGICLGMQLAVIEFARNCLNLKDANSTEFDPN----TPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTEN--SILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIIELTGHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGTLNTHLQQMSKLSY---SDIYSDASDDSF----SEAKFAELDIN----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRF8-1", "uniprot_id": "PYRG2_HUMAN", "id": "Q9NRF8-1", "name": "CTP synthase 2", "aln": "-------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSA-------SNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFRPN----APVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTEN--SILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSS---SDRYSDASDDSF----SEPRIAELEIS----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HG78-1", "uniprot_id": "A0AC58HG78_DANRE", "id": "A0AC58HG78-1", "name": "CTP synthase", "aln": "MKIVFTSEPCPINHCLSYIDRCCCIMKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKVSVDDDGIEPEVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPNSTGEQKTKPTQNSVRELRGLGLSPDLIVCRCSTPLDTAVKEKISMFCHVEPEQVICIHDVSSIYRVPLLLEDQGMVHYFCRRLDLPIQMRP-------RQMLRKWKEMSDRSDRLLEQTSIALVGKYTKLSDSYASVIKALEHSALAINYKLEVKYIDSAYLEPAALQDEPVKYHEAWQKLCSADGVLVPGGFGVRGTEGKIQAINWARKQKKPFLGVCLGMQLAVCEFARNVLGWEDANSTEFDPE----TKHPVVIEMPEHNPGQMGGTMRLGKRRTLFKSTP--SILRKLYGDAEYVDERHRHRFEVNPELKHHFEDRGFRFVGQDLEGERMEIIELEDHTYFVGVQYHPEFTSRPIKPSPPYFGLLLAASGKLQNYLQKGCRLSP---RDAYSDRSGTSS----PDSEISEFKFPSLS-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUL1-1", "uniprot_id": "PYRG_DROME", "id": "Q9VUL1-1", "name": "CTP synthase", "aln": "-------------------------MKYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTFSPYEHGEVYVLDDGAEVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPHITDAIQEWVERVAQTPVQGSS-KPQVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCLAHVSLVPLPKATGEPKTKPTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVICIHDLNSIYHVPLLMEQNGVIEYLNERLQLNIDMSKR------TKCLQQWRDLARRTETVRREVCIAVVGKYTKFTDSYASVVKALQHAALAVNRKLELVFIESCLLEEETLHSEPSKYHKEWQKLCDSHGILVPGGFGSRGMEGKIRACQWARENQKPLLGICLGLQAAVIEFARNKLGLKDANTTEIDPN----TANALVIDMPEHHTGQLGGTMRLGKRITVFSDGP--SVIRQLYGNPKSVQERHRHRYEVNPKYVHLLEEQGMRFVGTDVDKTRMEIIELSGHPYFVATQYHPEYLSRPLKPSPPFLGLILASVDRLNQYIQRGCRLSPRQLSDASSDEEDSVVGLAGATKSLSSLKIPITPTNGISKSCNGSISTSDSEGACGGVDPTNGHK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38627-1", "uniprot_id": "URA8_YEAST", "id": "P38627-1", "name": "CTP synthase 2", "aln": "-------------------------MKYVVVSGGVISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGITLSRDHNITTGKIYSHVISRERRGDYLGKTVQIVPHLTNAIQDWIQRVSKIPVDDTGLEPDVCIIELGGTVGDIESAPFVEALRQFQFEVGRENFALIHVSLVP--VIHGEQKTKPTQAAIKDLRSLGLIPDMIACRCSEELNRSTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLKQHMIDYLHSRLKLGEVPLTLEDKERGSQLLTNWENMTKNLDDSDDVVKIALVGKYTNLKDSYLSVTKSLEHASMKCRRQLEILWVEASNLEPETQEVDKNKFHDSWNKLSSADGILVPGGFGTRGIEGMILAAKWARESGVPFLGVCLGLQVAAIEFARNVIGRPNSSSTEFLDETLLAPEDQVVIYMPEIDKEHMGGTMRLGLRPTIFQPNSEWSNIRKLYGEVNEVHERHRHRYEINPKIVNDMESRGFIFVGKDETGQRCEIFELKGHPYYVGTQYHPEYTSKVLEPSRPFWGLVAAASGTLGEVIKDINLSEG--------NENE----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P28274-1", "uniprot_id": "URA7_YEAST", "id": "P28274-1", "name": "CTP synthase 1", "aln": "-------------------------MKYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAKERKGDYLGKTVQIVPHLTNAIQDWIERVAKIPVDDTGMEPDVCIIELGGTVGDIESAPFVEALRQFQFKVGKENFALIHVSLVP--VIHGEQKTKPTQAAIKGLRSLGLVPDMIACRCSETLDKPTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLEQKMIDYLHARLKLDEISLTEEEKQRGLELLSKWKATTGNFDESMETVKIALVGKYTNLKDSYLSVIKALEHSSMKCRRKLDIKWVEATDLEPEAQESNKTKFHEAWNMVSTADGILIPGGFGVRGTEGMVLAARWARENHIPFLGVCLGLQIATIEFTRSVLGRKDSHSAEFYPD--IDEKNHVVVFMPEIDKETMGGSMRLGLRPTFFQNETEWSQIKKLYGDVSEVHERHRHRYEINPKMVDELENNGLIFVGKDDTGKRCEILELKNHPYYIATQYHPEYTSKVLDPSKPFLGLVAASAGILQDVIEGKYDLEA--------GENKFNF-------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***::*:******:***::*** * ::*: ** **:******:******:** **** :**:**.*.*********:*.: * :*:*:******. ** :** *:*******:***:*:*:*:*: . :: .*:. .*::*::*****:****. .*:**:*****.. :*** ****** ** ****** ::: **. ** **:*.**.. : . :**: **** *:**: :**:.* *:**:*: .: ::.*: ** * : * :*. : . : **:*****:: *.* ** *:*:*::: . :*:: :::: ** : : *:*. *: :. :.*:*:***** ** * : * *** . *:**:***:* *. **:*. :. :: ::*: : :*: *** . :**:**** * *.* * :::***: :.******:*:**: . :*...: *** * * **.** .*.*::..*:***: *: :.** *: **: *: . * :: . . ", "identical_positions": 247, "similar_positions": 167, "identity": "37.14%" }, { "cls_id": "homologset.agr.MGI:1933196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G3P6-1", "uniprot_id": "A0A8I6G3P6_RAT", "id": "A0A8I6G3P6-1", "name": "Helicase ARIP4", "aln": "-------------------------------------MSDESASGS--DPDLDPD------------EEEVAVEEHDRDDEEGLLDDPSLEG------------MCG-TEHAQLGEDGQRPPRCTSTTSSQSEPSEQLR-HQGKILASEDPKKK-------------------------------------RAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKEYAAPIPTVPLEFLPEEIVLRASDGPQ----------LPPRVLAQEVICLDSSSGSEDEKSS---------------RDEVIELSSGEE-DTLHIVDSSE-SVSEEDEEEE---KGGTHVNDALNQHDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADSKPEEIQPRFFKVHILNDEHKTVASRAKVTTDWVSEGGVLLMGYEMYRLLTLKKSLATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSQIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKEN------------------------------------------------------------------------------------------------------------------------------------LANEQDLDVEELGSAGTSTRCPPHGTKVKGEDSALPSSMGEATNSKFLQGVGFNP------FQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRDMPCPPGAEGQGAQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQTSLDIKG---------IKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTR----------------PSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDDKPVASVRPVQS------------TPIPMMPRHVPLGGSVSSASNTNPSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARISAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLASTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESHQNSPSISAALPGPPAQLMDNSTIPGTALGTEPCLGGHCLNSSLLVTGQPSSGRHPVLDLRGHKRKLATPSVSQESVRRRSRKGHLPAPVQPYEHGYPVSGGFSMPPVSLNHNLTTPFTSQAGENSLFMGSNPSYYQLS-NLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLN---PSVPGILPSYSLPFSQPLLSEPRMF-------APFPSPVLPSNLS-RGMSVYPGYMSPHAGYPAGG-LLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NG0-1", "uniprot_id": "ARIP4_MOUSE", "id": "Q99NG0-1", "name": "Helicase ARIP4", "aln": "-------------------------------------MSDESASGS--DPDLDPDVELEDEEEEEEEEEEVAVEEHDRDDEEGLLDDTSLEG------------MCG-TEHAQLGEDGQRPPRCTSTTSSQSEPSEQLR-HQGKILASEDPKKK-------------------------------------RAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKEYAAPIPTVPLEFLPEEIVLRASDGPQ----------LPPRVLAQEVICLDSSSGSEDEKSS---------------RDEVIELSSGEE-DTLHIVDSSE-SVSEEDEEEE---KGGTHVNDALNQHDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADSKPEEVQPRFFKVHILNDEHKTVASRAKVTADWVSEGGVLLMGYEMYRLLTLKKSLATSRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSQIQRDLYTQFMDRFRDCGTSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKEN------------------------------------------------------------------------------------------------------------------------------------LANEQDLDVEELGSAGTSARCPPHGTKVKGEDSALPSSMGEATNSKFLQGVGFNP------FQERGNNIVTYEWAKELLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRDMPCLPGAEGQGTQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCHIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQTSLDIKG---------IKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTR----------------PSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPVASVRPVQS------------TPIPMMPRHVPLSGGVSSASSTNTSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLASTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSVSAALPGPPGQLMDNSTIPGTALGTEPCLGGHCLNSSLLVTGQPSGGRHPVLDLRGHKRKLATPSVTQESVRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFMGSNPSYYQLS-NLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLN---PSVPGMLPSYSLPFSQPLLSEPRMF-------APFPSPGLPSNLS-RGVSVYPGYMSPHAGYPAGG-LLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4B4-1", "uniprot_id": "ARIP4_HUMAN", "id": "Q9Y4B4-1", "name": "Helicase ARIP4", "aln": "-------------------------------------MSDESASGS--DPDLDPDVELEDAEEEEE-EEEVAVEECDRDDEEDLLDDPSLEG------------MCG-TEHAQLGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKK-------------------------------------RAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIALRASDGPQ----------LPPRVLAQEVICLDSSSGSEDEKSS---------------RDEVIELSSGEE-DTLHIVDSSE-SVSEDDEEEE---KGGTHVNDVLNQRDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKES------------------------------------------------------------------------------------------------------------------------------------LANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNP------FQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQVSLNVKG---------IKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTR----------------PSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPVASVRPVQS------------TPIPMMPRHVPLGGSVSSASSTNPSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKVPEDGRMAASGSQGPSCESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSTNAALPGPPAQLMDSSAVPGTALGTEPRLGGHCLNSSLLVTGQPCGDRHPVLDLRGHKRKLATPPAAQESSRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFMGSTPSYYQLS-NLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLN---PSVPGILPSYSLPFSQPLLSEPRMF-------APFPSPVLPSNLS-RGMSIYPGYMSPHAGYPAGG-LLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLB3-1", "uniprot_id": "A0A8M2BLB3_DANRE", "id": "A0A8M2BLB3-1", "name": "", "aln": "-------------------MRSEWRCVSNALGDPGDAMSEEAISGSDLEPSLNSEEEEEEEEMDEEEEEDGENDGDDEEDAGDQLESLEMEDRRDPSSPAPTSPMSGDSSPERLSRPASRPSSTSRTSSRPGSQPPSSPDTRSNASANSNTKKKT-----------------------------------SKTSKPAHLRRNIRKLLTENQLEAGTKAAQQEELERRRRLEQQRKEFS----------LHADLATAAAGS------------------KQEVICLDSSGDEGEEKEAP-------PPPLPDHRDDVIELSSGDEGDALRISSEEEEDRSLTPGTEE---SSGSHINDSLNQPDSQGRVLININHPAEEEDLFLAPQLARAVKPHQIGGIRFLYDNLVESLERYKTSSGFGCILAHSMGLGKTLQVISFIDVLLRHTGAKTVLAIVPVNTLQNWLAEFNLWLPAAEALPPDTDPQQVLPRTFKVHILNDEHKTTVARAKVVEDWTGDGGVLLMGYEMYRLLSLKKSFVTGRKRKSKKPAGPVIIDLDEEDRQQELMKAIERALSRPGPDVVICDEGHRIKNCHASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVQLMRYRSHVLHSLLEGFVQRRGHDVLRHQLPPKEEHVILVRLSRLQRALYTEFMNRFREAGNSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKEN------------------------------------------------------------------------------------------------------------------------------------LANEQDLDLDDLNSS-SGTRCSAPGIKSKTSD---------AANSRQMSVGHLNP------LQEKANQVITYEWAKEVMTNYQTGVLENSAKMVLLFYLIDETVARGDKILVFSQSLSTLTVIEDFLSRRPMPIQTET---GTHNWVRNINYYRLDGSTSASERERLINQFNDPANTQAWVFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQRKPCHIYRLVCDFTLEKKIYDRQVSKQGMSDRVVDDLNPVLNFTRKEVESLLHFVEEEPDP-AELQPNN---------EMETVIQQACVMYPHLLTKPPFHHESLLMDRKEMKLTKAEKRAAKKSYEDEKRASVPYQR----------------PSYAHYYPASDQRLTNIPAFSQRNWRPPPHLEEKPVASVRPVQS------------TPIPMMPRQVPMG--VPSSSTG-----FPVNYLQKAGVYVQRVVTTTDIVIPGSNSSTDVQARIGAGESIHVIRGSKGTYIRTNDGRIFAIRS-GKPRPPEGGATASREDCGPPLHSVSNGRASPQEPKRLTPEALPRPSSRESPRFHREFHSNKEAVASAENLTSSG--TPESTGADRPIQHPSHLPEQHR-------------------QLSNDIASSVDVQSLKRKLLESRTSKQPGGKRTSTSTSAAGSYP---GFPLNSGFGFPSMALNPALLGALGHVTPPS---LGSRSHLMQQAGQTLGDLHAMFPTEPLGLGVSNSTLSSTCSTNTTSSSHSGMLASSSSSVPSSSLSSTSSSLPPFMMNPSMASMLSGFPVPFSQPLFPGSLHPRGLSSTSTPASTASSFLSSSSLLGTAFSRPDTHP----SLTENGGSSSDDDVIEVMGQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1A8-1", "uniprot_id": "Q9W1A8_DROME", "id": "Q9W1A8-1", "name": "Helicase ARIP4", "aln": "MDNPEANMEESNPNYDVNQRLQKPEGWPHVNEFHPSMMYPDDPRRYFHNASTDPQHQPQQHPQQQPEQHPEQHPQHPLHSQQQPQQHPQQQPQQHPQQQTQQPPQLQPQQHPQAQIQPPIPVPISTPMEGTMEVPVKMPEYCPETSQPVEPDRVINPLAEVAKNTVPYGHKRKNSAGEDQAANKKLSMAAAEEKKNSHLRKNIRDVMNENNLDTTTLAAQREESERLARVAGQQKSMREIQKQVVHKQIFRILQLDESEGIESCAVANPVEHHPPVDFPEEEIASDTFDDSNSSSLSGGSIEDVLHKGASVQPSEVVTIDDSSDDDCILLSEEEEEEDDEDLNESDDATNSGMHVKDIYNVPDENGQVVVNMAHPEGEETLYLAPQIAKVIKPHQIGGVRFLYDNIIESTRRYNKSSGFGCILAHSMGLGKTLQVVSFCDIFLRHTSAKTVLCVMPINTLQNWLSEFNMWIPR------YSTDSNVRPRNFDIFVLNDQQKTLTARAKVILNWVHDGGVLLIGYELFRLLALKLVKTRKRKGS--------VIRPDGMDSSSDLMNLVYEALVKPGPDLVICDEGHRIKNSHAGISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRPNYLGTRTEFCNMFERPIQNGQCVDSTPDDIKLMRYRAHVLHSLLLGFVQRRSHTVLQLTLPQKYEYVILVKMTAFQRKLYDTFMTDVVRTK----AFPNPLKAFAVCCKIWNHPDVLYNFLKKCETDLDLEIDEEVTKGAATPIVEPSADSSLSLASPLEKKINGSGDPINSIETFSKAENQTLFNIPASSDLNAKYLNKSPSFYDEKPEPLNYGSFGSEGKNNYWMDSSILPKPGCVEVIKQTDTNMSSNFESITGSSEIVDLDTNEIKTVETTIQAPCSNNQLDNGCNAGKPSEWNAAGSKNSSGVAAAEPFKKLLKSKQRNEEFSCSWAVDLMKNYVSGLISNSPKMEIFFCILKESLNLGDRILLFSQSLLTLNLLEVYLKSSYVPG-------SNQLWTKNSSYFRLDGSTSSQERERLVNEFN--ANSNVKLFLISTRAGSLGINLTGANRVIIFDASWNPCHDTQAVYRIYRYGQTKPCFVYRIVMDRCLEKKIYDRQIKKQGMSDRIVDECNPEAHLSMKDITNLCQDYDSDEDTVEEVNKSTGDLSKPGSPSEEGSKPGSANMSPNASNKSNNGPTKPLDDQNTPKSPNGASHSPIKTEKNDGQEHAVHVDGIINTILDMHRHCVTKEPFMHESLLVDQKDRKLSQAEKRQAHRSYELEKKAAVNQRFTYAPAKMNYKIVNNDGTVITKPMNQQIKTNTSSSTGGRSTRWIPADVWQRQGMTAQEMTLPLDVVIP-TNSADKANIILKAGQRVMVLKSAKGIYMQLDSGKIIAIRTTAKTEP-------EKTNKDDVIDITDDGDTDTTKPQSPE-EDVKDLTADDEPRVVKNKESNPATTSRPEMPAKDRKSTENVQHFKSQTQPNTTLATTTN------------------------QHQLPSDLTYSQPQQSHQQPQQQASQQQPAQQPPPPAYKHQNHLPAAGEGYSNANSIQPNVPLPPHPGAPNSSEAPPPADSSYFQPKPFQHTYPPQYYDYYDNKHKSAPPGSGYHINNYTSYGNLNFAP----------YHSNLHPPASYIGAPSSY---------VNSNVFPRQHWSSVVNSSPASSESMRQPSYIG---------------------------STYPVNEWSSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :.. :.: :. .. : . : . : * : . . . . . : :..: . .* :*:*:***.:: *::*:. * ***:** ** *: *:*. : : : . :* *. *: ... ... : .:*: :....: * : : ...* . . .: ..* *::* * * *:*::*: ** ** ::****:*:.:*******:******::** .*::.********************:** *:::*** *****.::*:*******:***:*:* . .:: ** *.:.:***::** .:**** :*. :*****:***::***:** . * . :* * * ..:: . . .** :****:***********.:*. * ***:**:***:***********:***********::**** **.******* ****:****:*::*****:******* ******.* **: ** * * ****::: :** ** ** . ******.*************: *:* . :: *** ::: : : :.. . : . *:.*: . .:: *: .: .** :::.** :*::.**.** ::* ::.*:: **:**:***** ** ::* :* :* . : *.:* .*:******.: *****:*:** :* . :**:*****.**:** *****::**********:*** *:***** ***.:**:* * *********:.*******:**: ** ::: *:: .* : :.: . .:: . * :. *: .* . * ::: * .:. .::. *: ::: : . : .: : ** .:. .:*: : . . :.*.... * . : .: * : : ..*:: :* : *: *: .*.:. . *:*** **: ..: : **: : :::.:** *:: ..*:*:*:*: .*.. . . ..:* .. .*: * : : :.*.. : .. ..: * .. . : :. . .: .:: :: .. * . . ::: : . : . . . : : . *. .. *: . : . . : * . . :* . :. . .. . . * * .:", "identical_positions": 419, "similar_positions": 408, "identity": "23.61%" }, { "cls_id": "homologset.agr.MGI:1933198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W15-1", "uniprot_id": "IBPL1_MOUSE", "id": "Q80W15-1", "name": "Insulin-like growth factor-binding protein-like 1", "aln": "MPR--------LPLLLLLLPSLARGLGLRDAGRRHPECSPCQQDRCPAPSPCPAPWISARDECGCCARCLGAEGASCGGPVGSRCGPGLVCASRASGTAPEGTGLCVCAQRGAVCGSDGRSYSSICALRLRARHAPRAHHGHLHKARDGPCEFAPVVLMPPRDIHNVTGTQVFLSCEVKAVPTPVITWKKVKHSPEGTEGLEELPGDHVNIAVQVRGGPSDHETTSWILINPLRKEDEGVYHCHAANAIGEAQSHGTVTVLDLNRYKSLYSSVPGDLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BN16-1", "uniprot_id": "B0BN16_RAT", "id": "B0BN16-1", "name": "Insulin-like growth factor-binding protein-like 1", "aln": "MPR--------LLLLLLLLPSLAWGLGLRDAGRRHPECSPCQPDRCPAPTPCPAPWISARDECGCCARCLGAEGAGCGGRVGARCGPGLVCASRASETAPEGTGLCVCAQRGAVCGSDGRSYSSICALRLRARLGTRAHHGHLHKVRDGPCEFAPVVLMPPRDIHNVTGTQVFLSCEVKAVPTPVITWKKVKHSPEGTEGLEELPGDHVNIAVQVRGGPSDHETTSWILINPLRKEDEGVYHCHAANAIGEAQSHGTVTVLDLNRYKSLYSSVPGDLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WX77-1", "uniprot_id": "IBPL1_HUMAN", "id": "Q8WX77-1", "name": "Insulin-like growth factor-binding protein-like 1", "aln": "MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISALDECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * *** ***.*: .**:**.* *:*:*.**: : ****:***** *** ***************.*** .*.**********:*: :**************:*********.*:******** .*** *****.***********::***.:*****:** *****:*********:**.:*****:.***********************:*:***************:***** :***:**.*******.:*:*:: ..*.* :", "identical_positions": 205, "similar_positions": 48, "identity": "73.74%" }, { "cls_id": "homologset.agr.MGI:1933199", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A7F2-1", "uniprot_id": "A0A8I6A7F2_RAT", "id": "A0A8I6A7F2-1", "name": "", "aln": "MESREILSSSRQRGSESEFLPGSSSRSPATPGCSGE-------PLKGISVGGERIEPEEEDELGSGRDVDCNSNADSEKWVAGDGLEEQEFSIKEANFSEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNGKATKEEERNHSKKKLLTASDPAASDLKGFQTQAYERPQKHSTLQYDPGLSQGFTSDTLKPKHQQKSSSQSHMDWSSNSDSG---PATQNCIISPESGRDTTSTSKIPALEPVASFAKTQSKKGSTGST----WSQLSSSSKDLLLGSVVPSPGSHSSPATPSNSAECNGLQPLGDQEGGGTKDLPEPPTISSKKKSSKKDLISQTIPNSDLDWVKSAQKAFETTEGKRET--YSADNAQETSPTRQSISSVSNPENDSSHVRITIPIKTPSLDPTNHKRKKRQSIKAVVEKIIPEKALASGITMSSEVVNRILSNSEGSKKDPRVPKLSKMIENESPSVGLETGANAEKIVPGGVSKQRKPPLVMTSPTRAEHAPSGKLPEIQHPKFAAKRR--CSKAKPPAMLREAVLATAEKLMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSS--VALKAKAPP--ETSPGAASIESKLGKQINVSKRGTIYIGKKRGRKPRTELPPPSEEPKTAIKHPRPVSSQPDVPAVPSSFQSPVAS-SPAAVHPLATQLGGSHGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPPDTSTKNRHGHRQKHL---IVDTFLAHESLKKPKHKRKRKSLQNRDDLQFLAELEELITKFQVFRISHRGYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMP----MMNLGYYGQYPAPLYLSHTLG-AASPFMRPTVPPPQFHTSSHVKMSGATKHKAKHGVHLQGTVGMGLGDIQPSLNPPKVGGAALSSSRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHLLSERLNSSDKELPLVSEKSKHKERQKHQHG-DASHKVSKNNFEVDTLSTLSLSDAQHWTQAKDKGDLSNEPVESCAKRYSGSGGD--STRSESLDVFSEMNPSSDKWDSDMSGSKRRGFEGFGTYREKDIQAFKMNRKERGSYESSMTPGMPSPHLKVDQTTVHSKSEGSVSTMMARKKPTAVDSVAIPSAPVLSLLAASAATSDAASSSLKKRFK-RREIEAIQCEVRKMCHYTKLLSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPSQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLALEPASGQDAVMATIEAVIHMAREAPPLPPPPPPLPPPPPPPP-PPPPPLPKTSRGGKRKHRPQPPAQPAQ--PPPQPLPQEEEVKAKRPRKSRASESDVLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z180-1", "uniprot_id": "SETBP_MOUSE", "id": "Q9Z180-1", "name": "SET-binding protein", "aln": "MEPREMLSSCRQRGSESEFLQGSSSRSPPAPGCSGE-------PLKGISVGGERMEPEEEDELGSGRDVDCNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRTGKNSKATKEDERNHSKKKLLTAGDPTASDLKAFQTQAYERPQKHSTLQYDPGHSQGFTSDTLKPKHQQKSSSQSHMEWSSNSDSG---PATQNCFISPEAGRDTASTSKVPALEPVASFAKAQSKKGSTGGA----WSQLSSSSKDLLLGSVVPSPSSHNSPATPSSSAECNGLQPLGDQDGGSTKDLPEPPTLSSKKKSSKKDMISQTLPNSDLDWVKSAQKAFETTEGKREA--YSADSAQEASPARQSISSVSNPENDSSHVRITIPIKTPSLDPSNHKRKKRQSIKAVVEKIVPEKALASGISMSSEVVNRILSNSEGSKKDPRVPKLGKMIENETPSVGLETGGNAEKIVPGGASKQRKPPMVMTSPTRTEHAPSGKLSEIQHPKFAAKRR--CSKAKPPAMLREAVLATAEKLMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSS--VALKAKAPP--ETSPGAASIESKLGKQINVSKRGTIYIGKKRGRKPRTELPPPSEEPKTAIKHPRPVSSQPDVPAVPSSFQSPVAS-SPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHGGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHL---IVDTFLAHESLKKPKHKRKRKSLQNRDDLQFLAELEELITKFQVFRISHRGYTFYHENPYPSIFRINFDQYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMP----MMNLGYYGQYPAPLYLSHTLG-AASPFMRPTVPPPQFHASSHVKISGATKHKAKHGVHLQGTVGMGLGDIQPSLNPPKVGGATLSSSRLHKRKHKHKRKHKEDRILGTHDNLSGLFAGKATGFSSHLLSERLSGSDKELPLVSEKSKHKERQKHQHG-EASHKVSKNNFEVDTLSTLSLSDAQHWTQAKDKGDLSSEPVESCAKRYSGSGGD--STRSEGLDVFSEMNPSSDKWDSDMGGSKRRSFEGFGTYREKDIQAFKMNRKERGSYESSMSPGMPSPHLKVDQTAAHSKSEGSISAMMARKKPTAVDSVAIPSAPVLSLLAASAATSDAASSSLKKRFK-RREIEAIQCEVRKMCHYTKLLSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPSQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLALEPASGQDAVMATIEAVIHMAREAPPLPPPPPPPLPPPPPPP-PPPPPLPKTARGGKRKHRPQPPAQPAQ--PTPQPLPQEEEVKAKRPRKSRASESDVLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6X0-1", "uniprot_id": "SETBP_HUMAN", "id": "Q9Y6X0-1", "name": "SET-binding protein", "aln": "MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSG---PVTQNCFISPESGRETASTSKIPALEPVASFAKAQGKKGSAGNT----WSQLSNNNKDLLLGGVAPSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQKAFDNTEGKREG--YSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKKRQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSS--VALKAKAPP--ETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVAS-SPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHL---IVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEELITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMP----MMNLGYYGQYPAPLYLSHTLG-AASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSASLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLVSEKNKHKEKQKHQHS-EAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFK-RREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6S3-1", "uniprot_id": "A0ACD6B6S3_DANRE", "id": "A0ACD6B6S3-1", "name": "", "aln": "MEQRDLTRTARPKGNE-EFFSTVTTINRADLSEVGLLAG----SIKSLPLPGEQQDHEEDEDLGLGKDMEVTSNADNERWGQGDGLEEQEFSIKEANFSEGSLKLKIQTTKRAKKPPKNLENYICPPEIRITIKQPGEQKSAKQAKNAKAGKEEEKGPPRK------------------RTYERPSK------LLGKTENVMMENTKPK-QSKSNDILHLDWTKKLDTVGEVGSQEQNRTEPETKKESACTNKGPLPEPSTPFLKTQVKKVADGLSGSHFGSAMSSPSTDLLAASSVNTVMSPSTDSSLFSFNKDRGLQQVTEQVFGNIK----------RKYGRKDPTKTPVMHNLDLQWVKKMDRDTENQDSAKEKQPYSQDKCAFEEEPEKPINRLDDDNKTTTGCGTHYTEES--------RSKKRRNRKVTEDSMVSNAQTVQQDEKTDNTDQGCTKLKVTKKTDVNAPKQFGFNLQQSQEDIAGTVTDDAEMFQN--RPRKTPAGRARSMIDVDKQTEGRQSKVKDRWLYLKSQ----NSSPHKDLNQSLSIE------EPPSAFPITPSSPLYTNTNSLTVITPVKKKRGRPKKQPLLTVETIHEGTATSPVSPIAHDSSNTSKRKK-HNMSKLVQLAFHKSPPAQQLQLKKSD-QEGVLKKR---TPTKIKEVKMQNIINELLSTSSSGNLAPKPNVPVSNAMSTVASTIEARFGKQINVSKRGTIYIGKKRGRKPRADLSSQQDEHKASDNHLLLNSSPFENPLVPSSNSSTTGMPSPRVMHSFSSHS-APGGAAHPVTTDTSQHDLKTMPNLQPISALPTKTHKGLLSSNWKLSPPRLMANSPSHLSEVASIKEVTLSPVSESHSEETIPSDSGIGTDNNSTSDQTEKGPASRRRYSFDLCSFDATEAAVIDAKSKAARGHYQKHVTAVSVENFFAQENLKKQKHRRKRKALQSQDDLQFMADLEELVSKFQVFRISHRNYKFYHENSYPSIFRLNFDHYYPMPYYPYDPLHYLRRSSD-KSKRRRGRPAKSDEPISKMPFIQGFGCPVPGGNYYAPYAMPYTSMPLATSMINMGYYGQYPSPLYLSHALGPTASPLMRPPVPPPKFHPGASSCLSASSRHRVKN-----MPHEMSSSRMSDSHHPS---SSCLGSVCLHKRKHKHKYKHKEDQYIQEREDLGGLFSGTQSPAFLSLLNERLEK--------NSLSKLKDKQRGKHSTDTSPKASRNYFEVDTLSSLSLSDSQHCKRTR--GETLNNFLNICTRQPHERLRA---SQDQPLDLFKGQHLGGD--DSSIH-IRRHSLEDFTTYKEGSMASFQGCSEER-----------------AEQMYQCS-------------------------------------TAVAEPSSYKRRSKLVEEVEEVQCDMRKKCAFSKILTTKKNLDHVNKILKVKRLQRQAKTGNNMVKRRRGRPRKQLLSLEEGLLGQMPVLEKCVDLPGKRNLHTGLVPAQLEFSN-HDSITDAIESVVNMARSQFS-----------------------PQSMQGGKNWQKIQPELQVER-----------PNRKGKGNRKEEATLASH--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: :.* :*.* :*: :: . . * . *.:.: **: : **:::** *:*:: .****.*:* ****************:******************************:*****.*:** :: .**.** **:*:. .:* ::****.* * .:.. :. *** *.**.. *::*:.: *: :: .**: ::::.*.* * ** :.* *:* ** : * : * :*. ..*** .. . : * .: :. . : .*** : :* *. * :* . *. : .: * **:***. :: :. :. :* ** *.. . ..: :. .: :: :: . :: : ***:. *.. :.::.: .. :.:. : . . .*.* ..** : ::: . * : ::. . :.*. . .:: .. : .:::. : * : :..* *.::: *****:************:******************************:*******::: ..*.***: :*::**.**. :. * .:::::*. : ***.*: * .*:* :* :**:*::** *** :* *.:.* *. *::**:::***********************::*.. .:* *:: :* ** : * ***. .* .. ** .:*.:::: .. * *.:*:*. :*****************:**: ...****************.*:.*:**:******************************:**.. ********:**:* .** *:.:* :** ***: *:.*:*:*.*** **:****:**.:*****:*:****::**********.*.*****.******:***:***:** **** ****:** ***::******:::.::*:**:***. *:*.*.*****.******* *:*:*******:******:** :***:***.****:**..: :*.:::*:.*: . *. . :. * :*. .: *.* ********* *****: : :::*.***:*. : :*.***. .. .* *::*: :*. ::. *.*:* *******:*****:** .::: *: .: :: *::: ::.: **:*. : ..* **.: :*:. *.* **:* .: :*: :** .:* * *: * ** *:* * .*:* :**::** * ::*:*:*************.******:*****:**:******** .::*. .********:***.**. :..* * ** : :*:: :**:*::***. . *:: :***. :: *. * : : *.* **...: :. ", "identical_positions": 650, "similar_positions": 452, "identity": "40.12%" }, { "cls_id": "homologset.agr.MGI:1933204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV05-1", "uniprot_id": "RBM5_RAT", "id": "B2GV05-1", "name": "RNA-binding protein 5", "aln": "------------------------------MGSDKRVSRTERSGRYGSIIDRDDRDERES-----------------------------------RSRR-RDSDYKRSSDDR---RGDRYDD-----------------------------------------------------YRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERES-------------------------------------KTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESVQSVDYYCDTIILRNIAPHTVVDSIMTALSP---YASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLPDG------NRVSAFSVASTAIAAAQWSSTQSQSGEGGNVDYSYMQPGQDGYTQYTQYSQDYQQFYQQQTGGLESDAS------ATSGTTVTTTSAAVVSQSPQLYN--QTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGT----KYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSNQQA-----GLPST--KEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKNSFQPVNSLREEERR----ESAAADAGFALFEKKGALAERQQLIPELVRNGDEE-NPLKRGLVAAYSGDSDNEEELVER-------------LESEEEKLADWKKMACLLCRRQFPNRDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAG-TVNYEQPTKDG--------IDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YE7-1", "uniprot_id": "RBM5_MOUSE", "id": "Q91YE7-1", "name": "RNA-binding protein 5", "aln": "------------------------------MGSDKRVSRTERSGRYGSIIDRDDRDERES-----------------------------------RSRR-RDSDYKRSSDDR---RGDRYDD-----------------------------------------------------YRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERES-------------------------------------KTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESAQSVDYYCDTIILRNIAPHTVVDSIMTALSP---YASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLPDG------NRVSAFSVASTAIAAAQWSSTQSQSGEGGSVDYSYMQPGQDGYTQYTQYSQDYQQFYQQQAGGLESDTS------ATSGTTVTTTSAAVVSQSPQLYN--QTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGT----KYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAEASSNQQT-----GLPST--KEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKNSFQPVNSLREEERR----ESAAADAGFALFEKKGALAERQQLLPELVRNGDEE-NPLKRGLVAAYSGDSDNEEELVER-------------LESEEEKLADWKKMACLLCRRQFPNRDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAG-TVNYEQPTKDG--------IDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52756-1", "uniprot_id": "RBM5_HUMAN", "id": "P52756-1", "name": "RNA-binding protein 5", "aln": "------------------------------MGSDKRVSRTERSGRYGSIIDRDDRDERES-----------------------------------RSRR-RDSDYKRSSDDR---RGDRYDD-----------------------------------------------------YRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERES-------------------------------------KTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESVQSVDYYCDTIILRNIAPHTVVDSIMTALSP---YASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLSDG------NRVSAFSVASTAIAAAQWSSTQSQSGEGGSVDYSYLQPGQDGYAQYAQYSQDYQQFYQQQAGGLESDAS------SASGTAVTTTSAAVVSQSPQLYN--QTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGT----KYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSHQQS-----GLPPA--KEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKNSFQPVNSLREEERR----ESAAADAGFALFEKKGALAERQQLIPELVRNGDEE-NPLKRGLVAAYSGDSDNEEELVER-------------LESEEEKLADWKKMACLLCRRQFPNKDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAG-TVNYEQPTKDG--------IDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NE58-1", "uniprot_id": "A0A8M1NE58_DANRE", "id": "A0A8M1NE58-1", "name": "", "aln": "------------------------------MGADKRVSRTERSGRYGSEQSRDD-DRRDR-----------------------------------RDRDDRGYDSHRWSDDR---RSDRYDGDRGDRGDRGD------------------------------------RGDRGDRYWSRDSPERGRKRRNSDGSEDGHHSDGDYSEHDYRGDPADEKES-------------------------------------KTIMLRGLPMNTSEADIRAAIDLLEGPKPMDVRLMKKRTGISRGFAFVEFYHLQAATRWMETNQKLLCVQGKPVVVHYSNNRHKFEDWLCNSCGLYNFRRRLKCFRCGAAKADSESSSTTGTTETQPSGDYYGDTIILRNIAPLSTVEAILGALAP---FANLLPGNIRLIKDKQTGQNRGFAFVQLASPLEASQLLTILQGLQPPLKLDGKTIGVDYAKSARKDLLLPDG------NRVSAFSVASTAIAAAQWSSSQPQQIVEPTSEYSYLQEG------YVPCSQEYQAYYQQQAGAVDPSLANGILGAAPGVKVVPAATGVVISQSAQVYQSPQAAQIEGKAQCITATATISAPATSAVSATATATSTSQENQANVPDTSSYQYDESSGYYYDPITGLYYDPNTQYYYNSQTQQYLYWDGEKQAYLPAVDSNAQNAM-----ASTSTPQKEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKSSFQPIS---QEERR----EAAAADAGFTLFEKKPGALER--LVTEASKMAEEESCSSKVGLVAAYSGDSE-PEELID--------------GDDREDKLTDWKKLACLLCRRQFPSKEALIRHQQLSDLHRQNLEVMRRSKLSEAELEELERKETEMKYRDRAAERREKYGIPEPPVPKKRKYTAPTPVVNYEQPTKDG--------LNSDNIGNKMLQAMGWKEGKGLGRNQQGITTPIEAQLRAKGAGLGTKGSSYNLTASDTYKDAVRKAMFARFTEIE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPY4-1", "uniprot_id": "Q9VPY4_DROME", "id": "Q9VPY4-1", "name": "RNA-binding protein 5-A", "aln": "MDSSSRRSFSGGSENEGGRGSDYYRSRPGSRYSRSRSRSRERNRSHGGIRHRNSRSRSRDRDRSPVFRNDQHRGGRGGAGNGDPDLYHSLINDDYRDQDERNYNSRSNFENRQFRRHDSFDRRHRDRDGESDRELNDYEYEQRSRDLDSRDRSSTDRDWYHNRSRSREHSRPWNRNNNHDDRSRSNERNTRHRDHRMYNGGGSNHNRDRDRDRDREQDRERDRDRDRDRERRGSSDYDSDEGHMRRNKYRSTTEALNIIIIFGLTKEMTRADIMSELIKVNMEPACIRIIRKQGTDSSRGIAFVEFNTVEEAKQWMDITQGVLKLNDERVSMRYSHKR--IQDWNCNKCGVCNFKFRFYCFVCKTSREDSETTFSSGSEGVDEVSTILTKKIMLRNLDALTNEEAVLTALQLHLKDLSKTVSKVLISRDSLTQASRGICYLHFDTLVDSMNVHNALTALDPPLTLDDRVVAITYCIDLEEQQALPKNPKELAVKDSTVNSGNISAVSPSGLGGNYTLADVPRLAEYSASLYASN-PAEHAYYVQYYTEYYTADINKNNRDSH-----LTEANSGAAVALSAIQRKQKKMSSIETTITAAATAAAQAAAQVKATLAAQVASAPKGNDGK----IYPTPDVTQYQYDETSGYYYDSTTGLYYNAHSQYYYNNETGAYLYWDQRRSTYVLATPASTQAALQEVLADAEQKGEEESKKAKEKE-----GGNKHDKVKVAKKIVKDMEKWAKQLNQKKDYTAVATPQPILAN-EVATTSRGNQGGYADVGFSILEKKE--------RGKLNDYAPNPTVGPMNKLVNAYGGTSDSEEDNAASSQNTQSSAVVSGGGGAEESDYVDFHKLTCLLCKRAFQSLEILQKHLKMSTLHKENLAKLNQN--TSSSIEEA------LAYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKQSTSATPAMPISSSNVGSRLLQKMGWSEGQGLGRKNQGRTQIIEADGRSNYVGLGNKSG--QMIPGNDYKSYIKKMMKQRYENA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A023GRW3-1", "uniprot_id": "A0A023GRW3_DROME", "id": "A0A023GRW3-1", "name": "RNA-binding protein 5-A", "aln": "MDSRYGHSFSGGNGNGSESG---YR-----RYSRSRSRSRERSRDRNEYRRRNSRSRSRE--RSSHYRNDRSP---------DRDLYRDLINEDYEDQG--NYNSRQNLDQR--HGEDKYDRRHADSQGRRD---HDSNYDKSGQDMD-KDR---DHRWKNYDRVSRER--------NHDDFDRGSERSSRSNDQRQFNNNGNSNSSSSYRDREKERDRDRRCSSDED------SDMASEFRQRGAYNSGSSVEPLNNIILFGLKKHVTEADIMGELIKVDLEPTSIRVMRKQQTGASRCFAFVEFKTVEEATRWMELTQGVLQLGDHRVTMQYSHTR--ISDWTCIKCGASNFKRRFQCYMCNASRAESENALYGAGEGVDEISQILTKKIMLRGLDALTNEEGVLTALQQRLPELAKTVSKVLVSRDALTNASRGICYLNFDTLIDSMNVFNGLTALDPPLTLDDKTVIVTYCIDSENRQMMP--------AEGNFFRAGETAMSPSAITAAYTLADVPRLAEYSASVYASN-PLEHANYVQYYTDYYTTEISKNCRDRQ-----VTEANSGAAVALSAIQRKQRKVSQMETTVS---------VTEAKVAFLARGESAPKGNDGK----KYDTPDVSKYQYDETSGYYYDHVTGLYYDAHSQYYYNNETGAYLYWDQKRSTYVLATPASTQAALKEVLADAEKK-EEEAKKAKEKEKEKEEAGGKPDKVKVAKKIVKDMEKWAKQLNQKKDYTAVATPQPILSDTEAATTSRASQGAYADVGFSILEKKE--------LGKLNDYVPEAGPPAISKLVGAYGGPSDSEDDNSAN-QKALEASVGTKRAISDESDYVDFQKLTCLLCMRAFQSLDILQKHLKMSNLHKENLDKLKRNPAVEAGTDEG------LSYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKDSFGATAAMPISSTNVGSRLMQKMGWSEGQGLGKKNQGRTEIIEADGRSNNVGLGNNTG--HMAPGNDYKSYIKKMMKQRYENA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* **. . *:. .. ..: . : : ::* * :* . *. .* :* . .. .:..*. . . * *:: : *:: ** :.:** : .: . : *: *. ** :***** :: *. **: .* * : .. : ::**: * :.** * .* **: *: *: * : : :** . ..*:**.: . : :.:: ** .:: : :* * .**:.:::: : ::: :: * .*.***.:*.:.: : :. . .: :. . :*::.: . . :** . :. * * :* : . . : . . ...: ..: :. :: . : . . : : *.. .. .**.: *****:****** *****:.::*****. * ***** .:.:*: *. :.:: :*.*: *** * *.*::*.****:***.**::*: : **: : :.. **.**:::*** : : ** **.* *: :: *.. .*::*::**** * * . : * :* ::* **::*: .:. . : : ***** *** *** .:** *:: : . :. *:. :. *:*.:::* *** **.***:: ** * ***: * : .*** : . : .: **. ::* * *: : ", "identical_positions": 189, "similar_positions": 255, "identity": "18.16%" }, { "cls_id": "homologset.agr.MGI:1933206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1M7-1", "uniprot_id": "NMD3A_RAT", "id": "Q9R1M7-1", "name": "Glutamate receptor ionotropic, NMDA 3A", "aln": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITANLSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLTTNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AIR5-1", "uniprot_id": "NMD3A_MOUSE", "id": "A2AIR5-1", "name": "Glutamate receptor ionotropic, NMDA 3A", "aln": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCU5-1", "uniprot_id": "NMD3A_HUMAN", "id": "Q8TCU5-1", "name": "Glutamate receptor ionotropic, NMDA 3A", "aln": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAPDDSRAGAQRDEPEPGTRRSPAPSPGARWLGSTLHGRGPPGSRKPGEGARAEALWPRDALLFAVDNLNRVEGLLPYNLSLEVVMAIEAGLGDLPLLPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSLVLHIPVISIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTQNNSKFHLGSIINITANLPSTQDLLSFLQIQLESIKNSTPTVVMFGCDMESIRRIFEITTQFGVMPPELRWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEHYVQDAMELVARAVATATMIQPELALIPSTMNCMEVETTNLTSGQYLSRFLANTTFRGLSGSIRVKGSTIVSSENNFFIWNLQHDPMGKPMWTRLGSWQGGKIVMDYGIWPEQAQRHKTHFQHPSKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSTLDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEKIAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLRGTAHMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAVFLTLYEWKSPFGLTPKGRNRSKVFSFSSALNICYALLFGRTVAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVEYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTANISELISQYKSHGFMDMLHDKWYRVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRLHRAINTSFIEEKQQHFKTKRVEK--------------------RSNVGPRQLTVWNTSNLSHDNRRKYIFSDEEGQNQLGIRIHQDIPLPPRRRELPALRTTNGKADSLNVSRNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTSRTCES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************************************** :..*******:**.** *.**** *******:*********** **** :*:***********:******************************:************************************************* ******:**************************************************************:******* *:*******.**:*******:*::.*:*****:******* ***:***::****: **:*:*********************************:*************************:*******:*:**************************:******:************:*****************:**** **************:**.***************************************** ** *****************************::********************************** ***:***************************************************************:************:*******.**********:*********.*************************************************************************************************:******************************************************:****************:******:**********************************************:**********************:***:****:**** ******* ***:**:** ***********:*****.********* : ******* ******* ***********:*.**:*******************************:*.*****", "identical_positions": 1029, "similar_positions": 64, "identity": "90.66%" }, { "cls_id": "homologset.agr.MGI:1933209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3E7-1", "uniprot_id": "D4A3E7_RAT", "id": "D4A3E7-1", "name": "Transmembrane 6 superfamily member 1", "aln": "MSASAATGVFVLSLSAIPVTYIFNHLAAQHDSWTIVGVAALILLLVALLARVLVRRKPPRDPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSVHYLMYLVMVAAIAWEESYRTIGLYWVGSIIMSIVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFRIYNQPSENYNYPSKVLQEAQAKTLLRRPFDLVLVMCLFLATGFCLFRGLIALDCPAELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVIALYGLVVPGCSWMPDITLVHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKIFFLALNVAYGVLPQLLAYRCTYSPEFFIRTKADEKLE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58749-1", "uniprot_id": "TM6S1_MOUSE", "id": "P58749-1", "name": "Transmembrane 6 superfamily member 1", "aln": "MSASAATGVFVLSLSAIPVTYIFNHLAAQHDSWTIVGVAALILLLVALLARVLVRRKPPRDPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSVHYLMYLVMVAAIAWEESYRTIGLYWVGSIIMSIVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFRIYNQPSENYNYPSKVLQEAQAKALLRRPFDLVLVLCLFLATGFCLFRGLIALDCPAELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVIALYGLVVPGCSWMPDITLVHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKIFFLALNIAYGVLPQLLAYRCTYNPEFFLRTKADEKLE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZW5-1", "uniprot_id": "TM6S1_HUMAN", "id": "Q9BZW5-1", "name": "Transmembrane 6 superfamily member 1", "aln": "MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPRDPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALDCPSELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFFIKTKAEEKVE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1TQE5-1", "uniprot_id": "A0A8N1TQE5_DANRE", "id": "A0A8N1TQE5-1", "name": "", "aln": "MDFPPEISVFLLSLTAPVILYTINHVPFLQDPQVMLTIGITVLTTIFLLANLSVKSKKSTDPLFYVFALFSFTSVVSITNALQQDGFIKGFMDFYISKAEPYLNTAHGVMMSYWDGVIHYCLLLFMIHCMSEGKPFRSLGLLWAGSMITSQIVVISGVIVGKYGKNLVPALCRHGPALLLSIWAAVRLFNRPRELSIIPADQLQQEQKKTLLSRPVDLLLTLGLLGNMAFNAFRGFVVLECSLDLCFSYIYQYEPYMKDSVGFPKVTMLVLLFYVFPLLFACVYGLHTPGCTWMLDWTLVLAGAVAQTQWTHLGASLHSRTPFTYRIPKDEWRTVVLLNLLTVALPVLLALRCYAKQSFFIRVHPEEQTRNGKKNN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .. .**:***:* : * :**:. :*. .:: :. :* : ***.: *: * . ******:*:*.*****.: .*:***:*.*** .*: :.*******:* *:.**** ** : *.*: .:: :.:*::** *.**:* * :*.:.* ******..: **: * *.:**..*::*:* * *:. :*: * * ** **.**:*.: *: .* ***::.*:*. :** * ***:**...:**: **. :** .* :. .:*** .***:** * **: **.:**:*::*:*****:**.:.**:*:: .: **: .** *** ** . .**::.:.:*: . ", "identical_positions": 154, "similar_positions": 126, "identity": "40.96%" }, { "cls_id": "homologset.agr.MGI:1933210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNG2-1", "uniprot_id": "TM6S2_RAT", "id": "B0BNG2-1", "name": "Transmembrane 6 superfamily member 2", "aln": "MDIPPLAGRTVAMSLGALPVSYVLNQVSAFSQPLCVVLTSALVLGLLFMAVYSLSHGEITYDPLYAVFVVFSFTSVVDLVIALQEDGYLMGLMDFYAKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSLLVFLPGNILGKYSSEIRPTFFLAILYMLVPCWAGMRIFNQSPAPSSCTCDVVQEEQKKSLLQRPADLTLIVYLILAAFFTVFRGLVVLDCPADACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALTFPGCSWLPDWALVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDTWATFLLSNLLFALGPHLLALRCLWRPAFFLRAAPPSSPQDQGKKQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1J1-1", "uniprot_id": "TM6S2_MOUSE", "id": "Q8R1J1-1", "name": "Transmembrane 6 superfamily member 2", "aln": "MDIPPLAGRTVAMSFCALPVSYLLNQVSAFSQPLFVVLTSALILGLLFLAVYSLSHGEITYDPLYAVFVIFSFTSVVDLVIALQEDGYMMGFMDFYTKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSILVFLPGNILGKYSSEMRPTFFLAILYMLVPCWAGVRIFNQSRAPTSYTPDMVQEEQKKSLLQRPADLALIVYLIFAALFTVFRGLVVLDCPTDACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALAFPGCSWLPDWALVFAGAIGQAQFSHMGASMHMRTPFTYRVPEDTWATFFLSNLLLALGPHLLAFRCLWRPAFFLHAALPSSPQDQDKKQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZW4-1", "uniprot_id": "TM6S2_HUMAN", "id": "Q9BZW4-1", "name": "Transmembrane 6 superfamily member 2", "aln": "MDIPPLAGKIAALSLSALPVSYALNHVSALSHPLWVALMSALILGLLFVAVYSLSHGEVSYDPLYAVFAVFAFTSVVDLIIALQEDSYVVGFMEFYTKEGEPYLRTAHGVFICYWDGTVHYLLYLAMAGAICRRKRYRNFGLYWLGSFAMSILVFLTGNILGKYSSEIRPAFFLTIPYLLVPCWAGMKVFSQPRALTRCTANMVQEEQRKGLLQRPADLALVIYLILAGFFTLFRGLVVLDCPTDACFVYIYQYEPYLRDPVAYPKVQMLMYMFYVLPFCGLAAYALTFPGCSWLPDWALVFAGGIGQAQFSHMGASMHLRTPFTYRVPEDTWGCFFVCNLLYALGPHLLAYRCLQWPAFFHQPP-PSDPLALHKKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1TQE5-1", "uniprot_id": "A0A8N1TQE5_DANRE", "id": "A0A8N1TQE5-1", "name": "", "aln": "MDFPPEIS-VFLLSLTAPVILYTINHVPFLQDPQVMLTIGITVLTTIFLLANLSVKSKKSTDPLFYVFALFSFTSVVSITNALQQDGFIKGFMDFYISKAEPYLNTAHGVMMSYWDGVIHYCLLLFMIHCMSEGKPFRSLGLLWAGSMITSQIVVISGVIVGKYGKNLVPALCRHGPALLLSIWAAVRLFNRPRELSIIPADQLQQEQKKTLLSRPVDLLLTLGLLGNMAFNAFRGFVVLECSLDLCFSYIYQYEPYMKDSVGFPKVTMLVLLFYVFPLLFACVYGLHTPGCTWMLDWTLVLAGAVAQTQWTHLGASLHSRTPFTYRIPKDEWRTVVLLNLLTVALPVLLALRCYAKQSFFIRVH-PEEQTRNGKKNN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:** . :*: * : * :*:*. :..* : . :* :*: . :.: : ***: **.:*:*****.: ***:*.:: *:*:** .:.****.****:::.****.:** * * * .: . * :*.:** * **: * :*.:.* *:***..:: *:: :*:. **.:::*.:. : . : :*:**:* **.**.** * : *: *. ***:***:*. * ** ********::*.*.:**: **: :**.:*: ..*.* ***:*: **:**:**.:.*:*::*:***:* *******:*:* * ..: *** . * *** ** :** : *.. **::", "identical_positions": 150, "similar_positions": 123, "identity": "39.68%" }, { "cls_id": "homologset.agr.MGI:1933212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3T1H2-1", "uniprot_id": "NGRN_RAT", "id": "Q3T1H2-1", "name": "Neugrin", "aln": "--------MALSLSLFLGGRVRAAVAR-CGFASQGVAGPGSISREP-----DPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFIPTLEQKLKQDQKVLKK--------------------------AGITRVVWQLPVSEDTLKPLSAGHPMSGPLLMPGDEVSSNSQTHSRALKVKSNAP-SAEAQK---------KREEKNKRIRVLAESLVPTTTALGHQRELQKYTTH---DSEADRRANNHILPSVEKLEELEAGEPGDQNFSSKVVQKG-------REFFDSNGNFLYRI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KS2-1", "uniprot_id": "NGRN_MOUSE", "id": "Q99KS2-1", "name": "Neugrin", "aln": "--------MALSLSLFLGGRVRTSLAR-CGFASQVMAGPGSVSCEP-----DPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFVPTLEQKLRQDQKVLKK--------------------------AGFTREIGQLPVSEDTLKALSAGRSVSG-LLMAGDEVSSKSQNHSTALKVAKSHPHSTDAQK---------KREGRDKRIQVLEESLVPATTALGHQRELQKSATS---DSEATGRAGSDTLPSAVLLEELKPGEPGDQSFSSKVVQRG-------HDFFDSNGNFLYRI----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPE2-2", "uniprot_id": "NGRN_HUMAN", "id": "Q9NPE2-2", "name": "Neugrin", "aln": "--------MAVTLSLLLGGRVCAAVTR-CGFATRGVAGPGPIGREP-----DPDSDWEPEERELQEVESTLKRQKQAIRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHEEFPESWSVPRLAEGFDVSTDVIRRVLKSKFLPTLEQKLKQDQKVLKK--------------------------AGLAHSLQHLRGSGNTSKLLPAGHSVSGSLLMPGHEASSKDPNHSTALKVIESDTHRTNTPR---------RRKGRNKEIQDLEESFVPVAAPLGHPRELQKYSS----DSESPRGTGSGALPSGQKLEELKAEEP--DNFSSKVVQRG-------REFFDSNGNFLYRI----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40156-1", "uniprot_id": "RRG9_YEAST", "id": "P40156-1", "name": "Required for respiratory growth protein 9, mitochondrial", "aln": "-----MNILRIACRSFHCLRCGPLLNENRGWSSKKIIK--LVNKSS-----LSNKEFTEKVRDGTKDIPEWKKQKMAVR----KKLQGQRWNPPKKISQEQMEALRLLKFNFPE-LTASDLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRR--------------------------GERIKEMYQRKEDAD----FVSNQIVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEK---------KNTNKLYILKHLGSKQ---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VBR0-1", "uniprot_id": "Q9VBR0_DROME", "id": "Q9VBR0-1", "name": "", "aln": "MTARMIQRGLHTARSCLLARAPRRANPGLGYQLEQLQEHPEKSSEASEDYADLESDFMDVQKTHRQYEREQQQHRDRIRQFMIKHKYFRDAKLPNLLLHAEKEQMRLLHERDPEEWSVERLAESFPATPDIVQKILRAKWRPRSVQRIRSHDETVIKNWQLLGTGKGDFSIPPSLLQHLQKFAERRWQDLRELKIQDWPTKSQLPTPQGNEFRKLLGSSSKTTEEMPTPQIPSGYEAPPSAAEDETYLLDKIRNKKKMRLQELKELQLVESAPAVPEEMKRPIENPSGTGFLPSFVPKFASSEIVISAADQRKYEITQVKTRIVIPRKLHRQGATYRVEDAYYDDDGELLYRVPGMTRASGDK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *: . : . .. :.:: : : :::: :* :: *. : * :* *: . .* :. **: * :.: ::::*:::: :. . :. : : : . . . . : * . .: . . : . :. : :: * ", "identical_positions": 14, "similar_positions": 65, "identity": "3.86%" }, { "cls_id": "homologset.agr.MGI:1933213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VDX6-1", "uniprot_id": "Q9VDX6_DROME", "id": "Q9VDX6-1", "name": "Serine protease K12H4.7", "aln": "---MAALRLVCLFVVLAIGLVQSLDIPKIKDVPLLVKTLKNLNRGPPHQVVTKR--ANVQEKWITQKLDNFNAS--NTQTYQMRYLLNDEFQTEG-SPIFIYLGGEWEIEESMVSAGHWYDMAQEHNGVLVYTEHRYYGQSIPTSTMST-EDL-KYLDVKQALADVAVFIETFKAENPQLANSKVILAGGSYSATMVVWFKRLYPDLIVGGWASSAPILAKVDFTEYKEVVGQAFLQLGGQ--KCYDRIENGIAELESMFANKRGAEARAMLRLCNSFDDQNDLDLWTLFSSISNIFAGVAQYQGTG--D-----IEYYCDYLLSFN-DDATAIANFVYWAWG--MGNCIDARYEGSVEYYLWGVDHFDAS--RPWYYQTCNEYGWYQSSGSRN---QPFGTKFPATLYINLCGDVFSSQYGNEQINNNAASTNEYFGGMEPGVDN----IYMTHGELDPWNPMGHGV----EQGATVIANASHCSDFGSIKSTDSDEMRASKEKLAELVRQWLA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDX5-1", "uniprot_id": "Q9VDX5_DROME", "id": "Q9VDX5-1", "name": "Serine protease K12H4.7", "aln": "----MKYTLVVLALLAPLTAAASLGEQKP-EANAFVKSLRELHRGPPVEPMKTR--AKVEERWITQKLDNFDDS--NNATWQDRIYINNKYFVDG-SPIFIYLGGEWAIDPSGITSGLWKDIAKQHNGSLLYTEHRFFGQSIPITPLST-ENLAKYQSVEQALADVINVIATLKQED-KYKDSKVVVSGCSYSATMATWIRKLYPEIIRGSWASSAPLLAKVNFKDYMKVVGESYATLGGQ--YCYDLIDNATSYYENLFEIGNGTQAVKELNLCSNFNVNSEQDRWQIFSTIANIFAGIAQYQKPEKYD-----IPTYCSILREFSDDDSVALSKFINWKINEHSGACLSTTFKGAVGYYEWSKENYQDSD-LPWIFQTCSEFGWFQSSGSRS---QPFGSTFPATLYEDTCEGVFGAKYDSAGIHANIRATNDDFGGLNVNATN----IYFVQGALDGWSKVGAGV----AQGATIIPYASHCPDTGSISASDSAELVASKKKLIKLVAQWLED---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A6H2EEF7-1", "uniprot_id": "A0A6H2EEF7_DROME", "id": "A0A6H2EEF7-1", "name": "Serine protease K12H4.7", "aln": "---MKWLNFSVQLICWMPSFLATFN--------PYRTNVELLNHEPVLGICSKNELASVEELWLDQKVDHFDKN--NNRTWKMRYYRNAKYFKPH-GPIYIFVGGEWTISPGLLSTGLTHDMAVENSGMLFYTEHRYYGLSLPFGNESYRLSNLKQLSLHQSLADLAHFIRHQKSNDPEMEDSKVILVGGSYSGSLVAWMTQLYPDLIAASWASSAPLLAKADFFEYMEMVGKSIQLSYGN--NCSLRIEKGFKFLVKLFDGDEIQELLYNLNGCVGYSPKNPLDRAAFFNGLGNYFALVVQSYSAS--------IPRLCETLMSLDSSDELAFIEFLKLLYSEGRRSSDCQDFGYSSMLELFTEDSVQSSETRAWFYQTCNEFGWYTTTKSKSSASQAFANQVPLGYFEQLCQDAFGAEQTAHQLAHGVEQTNSKFGGFGFNQSERYAQVIFTHGELDPWSALGQQK----GDQAIVLTGYSHVEDLSSIRVMDSVQMNLAKLRVMSFLRRHI-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ET22-1", "uniprot_id": "DPP2_MOUSE", "id": "Q9ET22-1", "name": "Dipeptidyl peptidase 2", "aln": "MNFHPCYPVDHGVPSWILVLLLSLG-------------LCNLQAR-----ADRVLDPDFHENYFEQYMDHFNFESFGNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSFANNSGFMVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYTQLLTVEQALADFAVLLQAL-RQDLGVHDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVVAVAGLGDSYQFFRDVTADFYGQSPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCQRLLNEGQRIMGLRALAGLVYNSSGTEPCYDIYRLYQSCADPTGCGTGSDARAWDYQACTEINLTFDSNNVT--DMFPEIPFSEELRQQYCLDTWGVWPRQDWLQT------SFWGGDLKAASN----IIFSNGDLDPWAGGGIQSNLSTSVIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLESTLIREWVAAARLKQPAMPRWPGPKKQHPSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EPB1-1", "uniprot_id": "DPP2_RAT", "id": "Q9EPB1-1", "name": "Dipeptidyl peptidase 2", "aln": "MGLHPCSPVDHGVPSWVLVLLLTLG-------------LCSLQAT-----ADSVLDPDFRENYFEQYMDHFNFESFSNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSLANNSGFIVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYTQLLTVEQALADFAVLLQAL-RHNLGVQDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVIAVAGLGNPDQFFRDVTADFYGQSPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTNFLGPLPANPVKVGCERLLSEGQRIMGLRALAGLVYNSSGMEPCFDIYQMYQSCADPTGCGTGSNARAWDYQACTEINLTFDSNNVT--DMFPEIPFSDELRQQYCLDTWGVWPRPDWLQT------SFWGGDLKAASN----IIFSNGDLDPWAGGGIQRNLSTSIIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLEATLIREWVAAARLKQPAEAQWPGPK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHL4-1", "uniprot_id": "DPP2_HUMAN", "id": "Q9UHL4-1", "name": "Dipeptidyl peptidase 2", "aln": "----------MGSAPWAPVLLLALG-------------LRGLQAG-----ARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRAL-RRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVT--DMFPDLPFTDELRQRYCLDTWGVWPRPDWLLT------SFWGGDLRAASN----IIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRG-GPRLSL---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : *: . ..* :: * :*:*: . .. *: * . .: .**::: *.* : .:. ::* :. . *.::***::* *:* * . : :.*:***. .: .: :: .: * **.. : .:: **.:: .. *:***::* ..: : :.. . *: * : .. .:* : * . . * . . : : . :. : . : . .* :*:*.* . : . . .. * ..:. : . :** : : : :* ** * * * : :* * : *. .: : :: . : ", "identical_positions": 55, "similar_positions": 128, "identity": "10.24%" }, { "cls_id": "homologset.agr.MGI:1933218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJP9-1", "uniprot_id": "A0ABK0LJP9_RAT", "id": "A0ABK0LJP9-1", "name": "Tudor domain-containing protein 1", "aln": "--------MMPRNNLEASTCKMAEPFNFEKKESKLPPHDSLRSPVPQHNHPNFRLKSPENGNKKNNFLLCEQNKQYLASQEDNSVVSSNPAGINGEVGGSKGDRKTLPTGNPVS-LSLGNNSPPNQVKTKPSNAVTPEKSKKSHKLFENALSVNNPALFNSLGPPLRSTTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSSHSTICRPVQQSLHKLEDNKSPFETKTIDVKNEVACPLGVTKEMTAGAERVMFSDLRSLQLRKSMEIKGTVTEFKHPGHFYVQLYSSEVLEYMNQLSASLKETYANMVPEDGYLPVKGEVCVAKYTVDQTWNRAVVEGVDVLQKKAHVLYIDYGNEEIIPVDRIHQLSRSISLFPPSAIKCYVSGVVPAAGEWTEDCVVAVKALLFEQYCSIKVVDISEEEGLTCAVDVVLQSSGKQLDHVLVEMGYGVKPDEPSSKKQSMDPGTSEDTGRLTAENRIGAERN---ALVPTVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGHKLAELQESLSEYCSHVTPRSDFYPTIGDMCCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLKRLCPIIPKLLDLPMQALNCVLAGVKPSLGMWTPEAICVMRKAVQNRMVTVRVVGMQGTRALVELVDKSVAPHLSASKALLDSGFAIEEKDIVADKGSSARASNVPLAVEGAVEVLEWTWVEFTVD-ETVDVMVCMMHSPGEFYCHCLKDDALKKLDDLNKSLADYCAQKPPNGFKAEVGRPCCACFAGDGNWYRALVKEILPSGNVKVHFVDYGNVEEVTTDQLHAIAPQFLLLPFQGMQCWLVDIQPKNKHWTKEATARFQACVVGLKLQARVVEITENGVGVELTDLSTPYPKIISDVLITEHLVLRCGSPQKDELMS--RPANKHN-QIDSQSVQASPPAEQ--------------------------WKTIELPVNKTVPANVLEIISPTLFYAIPSEMPENQEKLCVLTAELLEHCNAQKGQPPYRPRTGEACCAKYTNDDFWYRAIVLEASDSDVKVLYADYGNVERLPFSRVQPITASHLQLPFRIIRCSLEG---------------------------------------LTELNGSSSQPVMELLRNAMLNQSVALSVKAVS-----------KNVHAVSVEKCSENGMIN---------------------IAENLVMCGLAENLSSKRESASTKETPHSTD-CCCTELQKQIEKHEQILLFLLNNPTNQNKFIEMKKLLQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MV1-1", "uniprot_id": "TDRD1_MOUSE", "id": "Q99MV1-1", "name": "Tudor domain-containing protein 1", "aln": "--------MMPRNNLEASTCKMAEPFNFEKKESKPPPQDPLRSPVAQHNHPTFRLKSPENGNTKNNFLLCEQNKQYLASQEDSSVVSSNPAVVNGEVGGSKGDRKPPPTGNPVSPLSLGNSSPPNQVKTKPSSNVTPEKSKKSHKLFENALSVNNPALFNSLGPPLRSTTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSSHSTICRPVQQSLNKLEDNKSPFETKAIEVKSEVDCPPGVTKEITAGAERVMFSDLRSLQLKKTMEIKGTVTEFKHPSNFYIQLYSSEVLENMNQLSTSLKETYANVVPEDGYLPVKGEVCVAKYTVDQTWNRAIVQAVDVLQRKAHVLYIDYGNEEMIPIDSVHPLSRGLDLFPPSAIKCCVSGVIPTAGEWSEGCVAAVKALLFEQFCSVKVMDILEEEVLTCAVDLVLQSSGKQLDHVLVEMGYGVKPGEQSSTEQSVDHSALEDVGRVTVESKIVTDRN---ALIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGHKLAELQESLSEYCGHVIPRSDFYPTIGDVCCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLKRLCPIIPKLLDLPMQALNCVLAGVKPSLGIWTPEAVCVMKEMVQNRMVTVRVVGMLGTRALVELIDKSVAPHVSASKALIDSGFAIKEKD-VADKGSSMHTASVPLAIEGPAEALEWTWVEFTVD-ETVDVVVCMMYSPGEFYCHFLKDDALEKLDDLNQSLADYCAQKPPNGFKAEIGRPCCAFFSGDGNWYRALVKEILPSGNVKVHFVDYGNVEEVTTDQLQAILPQFLLLPFQGMQCWLVDIQPPNKHWTKEATARFQACVVGLKLQARVVEITANGVGVELTDLSTPYPKIISDVLIREQLVLRCGSPQ-DSLMS--RPANQHK-QIDSHRVQASPSAEQ--------------------------WKTMELPVNKTIAANVLEIISPALFYAIPSEMSENQEKLCVLAAELLEHCNAQKGQPAYRPRTGDACCAKYTNDDFWYRAIVLETSESDVKVLYADYGNIETLPLSRVQPIPASHLELPFQIIRCSLEG---------------------------------------PMELNGSCSQLVMELLRNAMLNQSVVLSVKAIS-----------KNVHAVSVEKCSENGMIN---------------------IAENLVMCGLAENLTSKRKSASTKEIPHSRD-CCCTELQKQIEKHEQILLFLLNNPTNQSKFTEMKKLLRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXT4-1", "uniprot_id": "TDRD1_HUMAN", "id": "Q9BXT4-1", "name": "Tudor domain-containing protein 1", "aln": "MSVKSPFNVMSRNNLEAPPCKMTEPFNFEKNENKLPPHESLRSPGTLPNHPNFRLKSSENGNKKNNFLLCEQTKQYLASQEDNS-VSSNPNGINGEVVGSKGDRKKLPAGNSVSPPSAESNSPPKEVNIKPGNNVRPAKSKKLNKLVENSLSISNPGLFTSLGPPLRSTTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVCRPVQPNFHKLE-NKSSIETKDVEVNNKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKD-YIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKS---DLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVD-QTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPND--RLVNKHELQVHVQGLQATSSAEQ--------------------------WKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEG---------------------------------------LMELNGSSSQLIIMLLKNFMLNQNVMLSVKGIT-----------KNVHTVSVEKCSENGTVD---------------------VADKLVTFGLAKNITPQRQSALNTEKMYRMN-CCCTELQKQVEKHEHILLFLLNNSTNQNKFIEMKKLLKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EK5-1", "uniprot_id": "TDRD1_DANRE", "id": "Q58EK5-1", "name": "Tudor domain-containing protein 1", "aln": "-------------------------MNPAFAQPMMRPNLPLRRPATGP-------------------------------------SSLSPRGPAPAIYEERLLASDVLDGPKIDTMRKDISQNCGDVLSSPQTAVSMMG--------------------------QVVKLCNYCSHQGNLRCTRCKKTCYCSVACQTQDWIAHRHVCKPSIPEVTSEK----PKESKAVPYANGLGGTQAKEISVDAQPKRIYRRDLHKKVVSKGSEIKGTVIDLRNPGMFSIHCQCEEMIESLKKITQQLQKTYCSSFAQE-YKPEVGELCAVKFSLDQNWYRAEIQAVDVARKTAGVFYIDFGNEENVALDHIRPLSENIDAVPPFALQCCIAGVKPLTGSWTGECCIAVRQLIAGKSLTFTVLDIMND-GDLLAVDSLVSTLGKHVSTFLIDQSYAIKEDVPVKTQTEHSISSLLTASFENFKRFSGGKNENSEARPPEPLTQGVGDSFTAVVTHLQSPSEILCQKLENASIIQQLQMNLRVHCSNTAASDDFRPAPGTVCCSLFSEDNQWYRAKVLAYSSEDRVCVGYIDFGNSEEVELNRLRPISKELLALATQAIPCSLAGIKSLTDTWSDEAVLMLKHLVCNRFIRVEILGKKDGRALVSMIDESSDPQASVTELLVNMGFAAIESVETKKNEPDPATSTEIPLSQPVVEKLEWTGAELPFDGQKVELVISTLKSLDEFYCYNYSKTDEHTLTEMSFELMKHCESERAP-FTPIVGEPCCALFTGDARWYRAMVLEVCGEGKARVCFVDYGNSCEVDAAHLKAITQSLLKLPFQAIRCWLAGVEPVEGQWKKEAMLRFQALCAGQPLSGKVLSITEKGYGMELESAG----QTVASVLISEHLAKPYGQVRQPPQIQPAKPASQIEDLPSLKPIDQNPSVEEPLKVSSKGAATTPEDLPVSSGCFPLNWKTLELSCSGTFQPRVAAVISPSLFYIMNPGQ-VNVEGLKAVMTDVAKYCSKQPVPNQCHPLPGASCCAQFSGDKNWYRAVVLEVTTKHAHVIYSDYGNMETVPLSSILPITKELLQHPFQIVRCALTGKEHFPVVWPTEVLELFGIQLSGGVLASFQGFDGTSNLLTLTQQSGQSDRDINSIILGALQKGQIKPSSKLPANVNEEKKDVEQKQTQPISSNKAVEQTLSTNVEKPALDDQTLPLSVSLKHEEPENMSKTKTAEECTSTPDTVSSIESSHAAQSCCCQELKQKMDRIEELVLLLVKQVGSR------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : *: .** * . * .* : .: . * :. .. :* .* . * . *: *. *.***::**:* ***.*** :** :* :*:* .. . : . *:* : . . . .: .:*: **:. : * ****** ::::*. * :: ..*::* ::::: .*::**.. :: * * **:* .*:::**.* ** :: *** ::.* *:***:**** :.:: : *...:. .** *::* ::.* * *.*: * *.: *: : :..::** :: **: : . ** :. .*:: .*.:* . ..: . . . .. . : ... * ** .***.* .**:*:*:*.:::**:*:.. : :** .* :*.: . .** *: * :**: ****:*****.****:**: * ***:*:** * :.* ** ** :** *. **: * ***:*. . *: **: :::. * *::: *.::. :**.::*:* *: *.:: *:: *** *. . .: .. :. : .: **** .*: .* :.*::::. : * .****: .. ..* ::. .* .:* .: . *.. :*.**** *:**. ****:* *: .*:.:* ****** ** : .*: * :* ****.::* *..::. : :*.:** *** .* *..:*:.:* :* *:** . . : ::.*** *:*. .. : . : ..: : : :: ....*: ***:**. . *. ..* :*** *** : * * * : ::: ::*. :* * :***:::.*. ****:** .: ....*:*:****:* :*:. : **. . * **:*:**:* * : .*...: : :: . : : .: * * : *:.:.:* :*. *: .::: *:: :. .:. . * : : *** **:::::: *.::*:*::: .: ", "identical_positions": 307, "similar_positions": 392, "identity": "23.85%" }, { "cls_id": "homologset.agr.MGI:1933227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7M6U3-1", "uniprot_id": "TEX14_MOUSE", "id": "Q7M6U3-1", "name": "Inactive serine/threonine-protein kinase TEX14", "aln": "MSRGAPFPVPCPVLLGTFTDDSLEAQLHEYAKQGNCVKLKKILKKGVCVDAVNTQGQSALFVAALLGHVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLTAGGDLRLHDEKGRNPQAWALTAGKDRSTQMVEFMQRCTSHMKAIIQGFSYDLLKKIDSPQRLIGSPPWFGSLIQGSPNSSPNRQLKPGIISAQNIYSFGFG------KFYLTSGMQLTYPGSLPVIGEKEVVQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLPTRPHCSRLRLADLLIAEQEHSSNLRHPNLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQVADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYLTESQDSGAHRNVTRMPLPTQLYNWAAPEVVLQKAATVKSDIYSFSVIIQEILTDSIPWNGLDGSLVKETIALGNYLEADVRLPEPYYDIVKSGIHAKQKNRTMNLQDIRYILKNDLKEFIGAQKTQPTESPRGQSYEPHPDVNICLGLTSEYQKDPPDLDIKELKEMGSQPHSPTDHSFLTVKPTLAPQTLDSSLSAQKPDNANVPSPPAACLAEEVRSPTASQDSLCSFEINEIYSGCLTLGTDKEEECLGTAASPEGDRPNQGDELPSLEEELDKMERELHCFCEEDKSISEVDTDLLFEDDDWQSDSLGSLNLPEPTREAKGKTSSWSKTDEY-VSKCVLNLKISQVMMQQSAEWLRKLEQEVEELEWAQKELDSQCSSLRDASLKFANA-KFQPAVGPPSLAYLPPVMQLPGLKQPENGGTWLTLARSPGNEREFQEGHFSKKPEKLSACGWKPFTQVSEESRGDCSELNNQLPTLRGPGKQSTGEQLPST---QEARESLEKNTNQNSRSMASVSSEIYATKSRNNEDNGEAHLKWRLAVKEMAEKAVSGQLLLPPWNPQSSAPFESKVENESTPLPRPPIRGPESTEWQHILEYQRENDEPKGNTKFGKMDNSDCDKNKHSRWTGLQRFTGIRYPFFRNHEQPEQNEASQASCDTSVGTEKFYS----------------------------------------TSSPIGDDFERFQDSFAQRQGYVEENFQIREIFEKNAEILTKPQFQAIQCAEDKQDETLGETPKELKEKNTSLTDIQDLSSITYDQDGYFKETSYKTPKLKHAPTSASTPLSPESISSAASHYEDCLENTTFHVKRGSTFCWNGQEAMRTLSAKFTTVRERAKSLESLLASSKSLPAKLTDSKRLCMLSETGSSNVSAAFVTS-THATKRKSLPRELAEATSQQHLDELPPPAQELLDEIEQLKQQQVSSLASHENTARDLSVTNKDKKHLEEQETNSSK-DSSFLSSREIQDL-EDTERAHSSLDEDLERFLQSPEENTALLDPTKGSTREKKNKDQDVVEQKRKKKESIKPERRESDSSLGTLEEDELKPCFWKRLGWSEPSRIIVLDQSDLSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M5M3-1", "uniprot_id": "TEX14_RAT", "id": "F1M5M3-1", "name": "Inactive serine/threonine-protein kinase TEX14", "aln": "MSRAVHFPVPCPVLLGTLTDDSLEAQLHEYAKQGNYVKVKKILKKGVCVDAVNTLGQSALFVAALLGYVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKVLTAGGDLRLHDEKGRNPQAWALAAGKDRSTQMVEFMQRCASHMKAVIQGFSYDLLKKIDSPQRLIGSPPWFGGLIQGSPNSSPNRQPKPGIISAQNIYSFGFG------KFYLTSGMQLTYPGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLPTHPHCSRLRLADLLIAEQEHSSNLRHPSLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSQFPVLHMEMIVHLLLQIADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYMMESQDSGAHRDMTRVPLPAQLYNWAAPEVVLQKTATVKSDIYSFSMIIQEILTDNIPWNGLDGSLVKETIALGNYLEADVRLPEPYYDIVKSGIHAKQKNRTMNLQDIRYILKNDLKEFIGAQKTQTTESPRGQRYEPHPDINICLGLTSEYQKDPPDLDIKELKETGSQPHSPTDHSFLTEK-TLAPQTLDSSLSAQEPDNPNVPS--ASRLAEEVRSPTPSEASLYSFEINEIYSGCLTLGTDKEEECPGTASSPEGDKANQVDELPSLEEELDKMERELHCFCEEDKSFSDVDTDLSFEDGDWQSDSLSSLSLPEPTREAKGKTSSWSKTDEY-VSKCVLNLKISQVMMQQSAEWLRKLEQEVDELEWAQKELDNQCRSLWDASLRFANT-KFLSAVGPPSLTYLPPVMQLSEPKQPENGGNWLTLARPPGNERDFQEGNFSKKSEKLSACDWNPFTQASEESRGYCSEPNNQPPTLCGPGKQNTGEQLPST---EEAKESLERNTNQNIRRMESVSSEVCDTKSRNNEDAGEARSKWRLAVKEMAEKAVSGQLLVPPWNLQSS--FESKVENESTPLPRPPIRGPESTDWQYILEYQREKDELKGNMKFGKMENSDCDKNKHSSWTGLQRFTSIIYPFFRNHEQPEHNEASQASCDTXCG-EKFYS----------------------------------------TSSPIEDDFERIQSSFAQPQGYVEENFQIREIFGKNAEILTKPQFQAVQCAEDEQEETLEETPKELKEKNISLTDIQDLSSITYEQDGCFKETSCKTPKLKHAPTSASTPLSPESISSAASHYEDCLEN-TFHVKRGSTFCWNGQEAMRTLSTKFTTVRERAKSLESLLASSKTLPAKLTDPKRLCMFGGACSSNISTAFVTS-THSTKRKSLPGELAEATSQHHIDELPPPAQELLDEIEQLKQQQVSSMVSLENTAHDLNVTENDKKHLEEQETNSSK-DSSFLSSREIQDL-EDTERAHSSLDEDLERLLQLPEENMTLLDPTKGSTREKKTKDQDMVEQKRKKKEGIKPERRKSDSFLGTLEEDELKPCFWKRLGWSEPSRIIVLDQSDLSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWB6-1", "uniprot_id": "TEX14_HUMAN", "id": "Q8IWB6-1", "name": "Inactive serine/threonine-protein kinase TEX14", "aln": "MSRAVRLPVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDERGQNPKTWALTAGKERSTQIVEFMQRCASHMQAIIQGFSYDLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVISAQNIYSFGFGKAMPWFQFYLTGATQMAYLGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLPTHPHCSRLRLADLLIAEQEHSSKLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLESEDRGVQRDLTRVPLPTQLYNWAAPEVILQKAATVKSDIYSFSMIMQEILTDDIPWKGLDGSVVKKAVVSGNYLEADVRLPKPYYDIVKSGIHVKQKDRTMNLQDIRYILKNDLKDFTGAQRTQPTESPRVQRYGLHPDVNVYLGLTSEHPRETPDMEIIELKEMGSQPHSPRVHSLFTEG-TLDPQAPDPCLMARETQNQDAPCP-APFMAEEASSPSTGQPSLCSFEINEIYSGCLILEDDIEE-PPGAASSLEADGPNQVDELKSMEEELDKMEREACCFGSEDESSSKAETEYSFDDWDWQNGSLSSLSLPESTREAKSNLNNMSTTEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQE-ERMSLWATSREFTNAYKLPLAVGPPSLNYIPPVLQLSGGQKPDTSGNYPTLPRFPRMLPTLCDPGKQNTDEQFQCTQGAKDSLETSRIQNTSSQGRPRESTAQAKATQFNSALFTLSSHRQGPSASPSCHWDSTRMSVEPVSSEIYNAESRNKDD-GKVHLKWKMEVKEMAKKAATGQLTVPPWHPQSSLTLESEAENEPDALLQPPIRSPENTDWQRVIEYHRENDEPRGNGKFDKTGNNDCDSDQHGRQPRLGSFTSIRHPSPRQKEQPEHSEAFQASSDTLVAVEKSYSHQSMQSTCSPESSEDITDEFLTPDGEYFYSSTAQENLALETSSPIEEDFEGIQGAFAQPQVSGEEKFQMRKILGKNAEILPRSQFQPVRSTEDEQEETSKESPKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSPGSVSSAASQYKDCLESITFQVKTEFASCWNSQEFIQTLSDDFISVRERAKKLDSLLTSSETPPSRLTGLKRLSSFIGAGSPSLVKACDSSPPHATQRRSLP--KVEAFSQHHIDELPPPSQELLDDIELLKQQQGSSTVLHENTASDGGGTANDQRHLEEQETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEESVELQDLPKGSERETNIKDQKVGEEKRKREDSITPERRKSEGVLGTSEEDELKSCFWKRLGWSESSRIIVLDQSDLSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.. :****** ***: :**********.**** **:*******: *****: **:********* *:************************************:* **********:*:**::***:***:****:*******:***:*:******************: **.* *.*:**.**.**** *.*:************ :****.. *::* ***********:************************ ************:********************:**** **********:**** ********:********************:*******::*** *** :**************:*.**********: **:* *.:*::**:***:**********:***:***********:*:******.***:*****:**:::. ***********:***********.***:*****************:* ***:**.***** * * ***:*: ******: ::.**::* **** ******* **::* ** **: *..* *::.:* :.*. *. :***. **:..: ** ************ * * ** *:*:* *.* .** *** *:********** ** .**:* *..:*: *:* ***..**.**.***.*****.: .. *.*:** :*****:*** *.:*::. : **::** ::*:* *** : : ** :* .*:*: *: ******* *:***:**. ::*:..*.: **.* * : : .:. *::.. : :.. :. .*: . : .* . ..* .. :. : : . * . : :.. : .****: ::***::* *:.: **:: *****:**.:*** :***: *** :**:.***. .* :****.**.*:** ::**:**:** :** **.* *.***.::*. . * **.* :* *::****:.** ***.** . ** ** ***** :*** :*.:*** * **:**:*:*: ******.:.***.::.:**:*:** *:*******: ***********:*: *. ***:* ****::*****.****** *:*****:*:****. **:** : ***.** ::*** .* :******.*:***:**:: *::**. ***. : : *..: * :* .*:*:*:*** .** **:*:******:*****:** ***** ** . **** * . * :*::*******:*.* ***:* *:* :** ********:******* ** ***. * * .*** **.: ***.: *:***:::.*.****:*:. *** ******.**********.*************", "identical_positions": 913, "similar_positions": 323, "identity": "60.7%" }, { "cls_id": "homologset.agr.MGI:1933237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z868-1", "uniprot_id": "D3Z868_RAT", "id": "D3Z868-1", "name": "Protein ZIP4 homolog", "aln": "--------------MDGIADLSIMDFKEVIKTMIITGNSWRLHEMIDKFFMNISNFNRKSLTEVQNIQIEEIAVNLWNWATAKRLELSVRKSQAAKLCYIACKLVCMHGVSVSSEEAIQRQILMNMKTGKQWLDTGNAQIADEFFQAAMANLEKLYSRLMQSCHTETNLSLYKNTVEKGIFHVLSYQAESAVAQGDFKKASICVLRCKDMLIRIPEMTKYLHVLCYNFGVESSKQNKYRESSFWLSQSYDIGKMGKDSVEPEMLAKGLRLLATIYLNCDDEAYYNKALIAVIVANKEHLDPAGLFLKMRILIKGKAFNEELLEAAKEVLYLAMPLEFCLSIIQFLIDNKRDSVGFCFLKIIADHFKLPEHRKRILLFYIDMLLQVDQDVIAEEKIKEILIDHQTRSRLTRALVNWLHNILWGKATRCVKVQNYADALRWYSYSLKLYECDQADMDLVKLKRNMVSCYLSLKQLDKAKEALAEAEQQDPTNIFTQYYIFKIAILDGEAYRALQIVSALKISMEE-DSEDCGLIENGVSTLRILSLCVEFALENEQQFVAQKALEYLIQLSKDPREVLEALKCLVRIILPQAFYLPESEIKKKEMNRLLSYLDTALLKFSQHFDDTSSTLDPMVNDANWFRKIAWNLALQSEKDLEKMKNFFMISYELSLFCPSDQGLLIAQKTCLLVAAAVDLEQGRKATTTYEQNKLLRMALEQIQKCKNVWNLLKQTGDFSGDDCGVMLLLYEFEVKTKTNDPSLHSFLQSVWKMPGLESRTLEIMASLAMDKPAHYPTIAQKALKKLLLIYRRKVPINVLRYSVCMHNLIDLLVSDRRWNMALYPLKEVWGHLKSALSLIRQTKGYPEEEIVWLMIKAWNIGILMYSRNKYISAERWARMTLEFLDHLGSLKTNYEAKMKLLYANLMEALDERLDLRSPEMTERIRALAVPPEGQGSVPSTNMAAHNHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14AT2-1", "uniprot_id": "TEX11_MOUSE", "id": "Q14AT2-1", "name": "Testis-expressed protein 11", "aln": "--------------MDRITDFYFLDFRESVKTLIITGNSWRLQEMIDRFFTNISNFNRESLTEIQNIQIEEIAVNLWNWAVTKRVELSVRKNQAAKLCYIACKLVYMHGISVSSEEAIQRQILMNIKTGKEWLYTGNAQIADEFFQAAMTDLERLYVRLMQSCYTEANVCVYKMIVEKGIFHVLSYQAESAVAQGDFKKASMCVLRCKDMLMRLPNMTKYLHVLCYNLGIEASKRNKYKESSFWLGQSYEIGKMDRRSVEPQMLAKTLRLLATIYLNCGGEAYYTKAFIAILIANKEHLHPAGLFLKMRILMKGNSCNEELLEAAKEILYLAMPLEFYLSIIQFLIDNKRESVGFRFLRIISDNFKSPEDRKRILLFYIDTLLQKDQDMIAEEKIKDVLKGYQTRSRLSRDLVNWLHNILWGKASRSVKVQKYADALHWYSYSLKLYEYDKADLDLIKLKRNMVSCYLSLKQLDKAKEAIAEVEQKDPTHVFTRYYIFKIAIMEGDAFRALQVVSALKKSLMDGESEDRGLIEAGVSTLTILSLSIDFALENGQQFVAERALEYLCQLSKDPKEVLGGLKCLMRIILPQAFHMPESEYKKKEMGRLWNYLNTALLKFSEYFNEAPSTLDYMVNDANWFRKIAWNLAVQSEKDLEAMKNFFMVSYKLSLFCPLDQGLLIAQKTCLLVAAAVDLDRGRKAPTICEQNMLLRTALEQIKKCKKVWNLLKKTGDFSGDDCGVLLLLYEFEVKTKTNDPSLSRFVDSVWKMPDLECRTLETMALLAMDKPAYYPTIAHKAMKKLLLMYRKQEPVDVLKYSVCMHNLIKLLVADEVWNISLYPLKEVQSHFKNTLSIIRQNEGYPEEEIVWLMIKSWNIGILMSSKNKYISAERWAAMALDFLGHLSTLKTSYEAKVNLLYANLMEILDKKTDLRSTEMTEQLRALIVPPEDQGSVSSTNVAAQNHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYF3-1", "uniprot_id": "TEX11_HUMAN", "id": "Q8IYF3-1", "name": "Testis-expressed protein 11", "aln": "MISAHCNLRLLCSSDSSASASQVAGTTEVVENLVTNDNSPNIPEAIDRLFSDIANINRESMAEITDIQIEEMAVNLWNWALTIGGGWLVNEEQKIRLHYVACKLLSMCEASFASEQSIQRLIMMNMRIGKEWLDAGNFLIADECFQAAVASLEQLYVKLIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRLPQMTSSLHHLCYNFGVETQKNNKYEESSFWLSQSYDIGKMDKKSTGPEMLAKVLRLLATNYLDWDDTKYYDKALNAVNLANKEHLSSPGLFLKMKILLKGETSNEELLEAVMEILHLDMPLDFCLNIAKLLMDHERESVGFHFLTIIHERFKSSENIGKVLILHTDMLLQRKEELLAKEKIEEIFLAHQTGRQLTAESMNWLHNILWRQAASSFEVQNYTDALQWYYYSLRFYSTDEMDLDFTKLQRNMACCYLNLQQLDKAKEAVAEAERHDPRNVFTQFYIFKIAVIEGNSERALQAIITLENILTDEESEDNDLVAERGSPTMLLSLAAQFALENGQQIVAEKALEYLAQHSEDQEQVLTAVKCLLRFLLPKIAEMPESEDKKKEMDRLLTCLNRAFVKLSQPFGEEALSLESRANEAQWFRKTAWNLAVQCDKDPVMMREFFILSYKMSQFCPSDQVILIARKTCLLMAVAVDLEQGRKASTAFEQTMFLSRALEEIQTCNDIHNFLKQTGTFSNDSCEKLLLLYEFEVRAKLNDPLLESFLESVWELPHLETKTFETIAIIAMEKPAHYPLIALKALKKALLLYKKEEPIDISQYSKCMHNLVNLSVPDGASNVELCPLEEVWGYFEDALSHISRTKDYPEMEILWLMVKSWNTGVLMFSRSKYASAEKWCGLALRFLNHLTSFKESYETQMNMLYSQLVEALSNNKGP--------------VFHEHGYWSKSD-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . * ::.:: ..** .: * **::* :*:*:**:*::*: :*****:******** : *.:.* :* *:****: * *.:**::*** *:**:: **:** :** **** ****::.**:** :*:* . .*::: : * **.. *:***************::**:***:*****:*:*:**. ** ****:*:*:.*.***.******.***:****.: *. *:**** ****** **: .. ** **: *: :****** ..******:**:**:: *******. *:*:* ***:* *.* ::*:*::*:**** ** ** :.** .*. ::*::: * *** .::::*:***:::: :** :*: :******** :*: ..:**:*:***:** ***::*. *: *:*: **:***..***.*:********:**.*::** ::**::******:::*:: **** : :*: : : :*** .*: *. :***. :***** **:**::***** * *:* .:** .:***:*::**: :**** *****.** . *: *::*:*: *.: . :*: .*:*:**** *****:*.:** *::**::**::* *** ** :***:*****:*.****::****.* **. :* ***:*:.*:.: *:**:** **.*.* :********::* *** * *::***::* ** :*:* :* :**:***:** ** **:** **:*::: *::: :** *****:.* *.* *: * **:** .:::.:** * :.:.*** **:***:*:** *:** *:.** ***:*. ::* **.** ::* .**:::::**::*:* *.:. . . :* ..:: ", "identical_positions": 464, "similar_positions": 290, "identity": "48.28%" }, { "cls_id": "homologset.agr.MGI:1933244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MX0-1", "uniprot_id": "TKTL1_MOUSE", "id": "Q99MX0-1", "name": "Transketolase-like protein 1", "aln": "MSEAEASSGMAHNAGPDEKTLQVLRDMANRLRIRSIKATNSSTTSYLIPCS-NAEIMSVLFFYTMRYKQEDPENPDNDRCILSKG---------------------------------------LPFVNVATGWPGQGLGAACGMAYTGKYFDQASYR---------VFCLLGDEESTEGSVWEAFAFASYYNLDNLMAIFDVNRIGHSSSMSVEHCIAIYQKRCEAFGWNTYVVD--GRDVKTLCHVFSQAAQVRGKPTAVVAKTFK---------------------------------ARGMPNVEDAESWYGRPMPKERADAIVKLIESQIQTNKILVPSPP--IEDSPQINIMNICMTSPPVYVADDKVSTQRACGLALAKLGHENDRVIVLGSDTKNCNFS-----------DIFKKEHPERFIQCCIAEQNMVNVALGCSTRDR-TIVFAYSFAAFFTRAFDQIRLGAISQININLIGCHCGVSTGDDNPYHMALEDLAMFRAIPNCVVFYPSDAVSTEHAVYLAAN-TKEMCFIRTSQAETAIIYTTQETFQIGQAKVVRHSDNDKVIVIGAGVTLHEALVAAAEL-SKEDISIRVIDLFTIKPLDIATIISNAKATGGRIITVEDHYPEGGIGGAVCAAVSMEPNIVVHNLAVMDVPRSGRCNEALDFSGISSRHIIVAVKCILMT--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPV2-1", "uniprot_id": "D3ZPV2_RAT", "id": "D3ZPV2-1", "name": "transketolase", "aln": "MSEAEASVGMAHDAGPDEKTLQVLRDMANRLRIRFIRTTSSSTTSYLTPCSSAAEIMSVLFFYTMRYKQEDPENPDNDRCILSKG---------------------------------------IPFVKVATGWPGQGLGAARGMAYTGKYFDQASYR---------VFCLLGDEESTEGSVWEAFAFASYYNLDNLMAIFDVNRIGHSSSMSVEHCVGIYQKRCEAFGWNTYVVD--GRNVETLCRVFSQAAQVRGKPTAVVAKTFK---------------------------------ARGMPNVEDAESWHGRPMPKERADAIIKLIESQIQSNKILVPSPP--IENSPQINIMDIHMASPPAYVADDMVSTQRACGLALAKLGHENDRVIVLDSDTENCNFS-----------DIFKKEHPERFIQCYIAEQNMVNVALGCATRDR-IIAFACTFAAFFTRAFDQIRVGAISQININLIGCHCGVSTGDDNPYHMALEDLAMFRAIPNCIVFYPSDAVSTEHAIYLAAN-TKEMCFIHTSQAETAIIYTTQETFEIGQAKVVRHSNDDKVIVIGAGVTLHEALVAADEL-SKEDISIRVIDLFTIKPLDSATIISNAKATGGRIVTVEDHYLEGGIGGAVCAAVSMEPNIVVHRLAVMDVPRSGRCNEALDFSGISSRHIIVAVKCILMN--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51854-3", "uniprot_id": "TKTL1_HUMAN", "id": "P51854-3", "name": "Transketolase-like protein 1", "aln": "MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDPENPDNDRFVLAKR---------------------------------------LSFVDVATGWLGQGLGVACGMAYTGKYFDRASYR---------VFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVD--GRDVEALCQVFWQASQVKHKPTAVVAKTFK---------------------------------GRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPP--IEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFS-----------EIFNKEYPERFIECFMAEQNMVSVALGCASRGR-TIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAAN-AKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADEL-SKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVP4-1", "uniprot_id": "Q9VVP4_DROME", "id": "Q9VVP4-1", "name": "transketolase", "aln": "----------MSNAKLDSKVVQNLKDVAQKLRIHSITSTQAAKSGHPTSCASLAEIMTVLFFQQMRLNLKHPRDPSSDRLVLSKGHAAPILYAVWAEA-GLFPVEELRNLRKVDSDLEGHPTPRLSFVDVSTGSLGQGISVAAGMAYVGKHLDKADYR---------TYVIVGDGEATEGAVWESLHFAGHYCLDNLCVIFDMNKIFCS---DIGTEMEVYRERLDAFGFNALVLN--GHDIDELAKAFINAASTKGKPTALLARTTK---------------------------------GKDFLGIEGIEEMHAQPLGKRAESAIKHLQMKIANPNVRLTPKKVGKCGHAPEVHINNIMLCSPPNYRLGDSVAPRLAYGTALAKIAADNPRVIALDGDTKNSTYA-----------DKMRNAFPERFIECFTAQQNLVGVAVGATCRRR-TVAFVSTYATFFTRAFDQIRMGAISHTNVNFAGSHCGCSIGEDGPSQMGLEDMAMFRSIPGSTVFYPTDAVSTERAVELAAN-TKGVCYIRTTYPSTTVIYNNDEVFAVGLGKVVRQKPSDEVLLIGAGVTLYECLAAAERL-EEDCITARVIDPFTVKPLDVGLIVKHGKLCRGRIVVVEDHYQQGGLGEAVLSALADYRNFVVKHLYITTVPRSGPPAVLLDMFGVSSRNIYKASLAIMKK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHN7-1", "uniprot_id": "Q9VHN7_DROME", "id": "Q9VHN7-1", "name": "transketolase", "aln": "----------MSYHKPEAKTVQDLKDLAQKLRIHSINATQASKSGHPTSCASIAEIMSVLFFQQLRLNLKHPRDPSSDRFILSKGHAAPILYAAWAEA-GLFPIADLNNLRKIDSDLEGHPTPRLNFIDVGTGSLGQGVAVGAGMAYVGKNFDKADYR---------TYVVVGDGESAEGSIWESLHFAGHYKLDNLCVIFDVNRLGQSEATSLQHKLDVYRDRLEAFGFNAVVVD--GHDVEELSKAFHCAAITKNKPTAIIAKTFK---------------------------------GRDFPNIEDLDNWHGKPLGDKAAEVVKHLEGLIVNKNVKLTPKPVPKTGAAPDVDINNIKLSSPPAYKLGDSIATRLAYGTALAKIGQNNLRVVALDGDTKNSTFS-----------DKLKNLDPQRYIECFIAEQNLVGVAVGAACRRR-TVAFVSTFATFFTRAFDQIRMGAISQTNVNFVGSHCGCSIGEDGPSQMGLEDIAMFRTIPGSTIFYPSDAVSTERAVELAAN-TKGVCFIRTSRPNTCVIYDNEEPFTIGRGKVVRQKSSDEVLLIGAGITLYECLAAADQL-EKNCITVRVIDPFTVKPLDAELIIEHGKQCGGRVVVVEDHYQQGGLGEAVLSALAGERNFVVKHLYVPTVPRSGPPSVLIDMFGISARHVVNAVNEILKD--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33315-1", "uniprot_id": "TKT2_YEAST", "id": "P33315-1", "name": "Transketolase 2", "aln": "----------------MAQFSDIDKLAVSTLRLLSVDQVESAQSGHPGAPLGLAPVAHVIFK-QLRCNPNNEHWINRDRFVLSNGHSCALLYSMLHLLGYDYSIEDLRQFRQVNSRTPGHPEFHSAGVEITSGPLGQGISNAVGMAIAQANFAATYNEDGFPISDSYTFAIVGDGCLQEGVSSETSSLAGHLQLGNLITFYDSNSISIDGKTSYSFDEDVLKR-YEAYGWEVMEVDKGDDDMESISSALEKAKLSKDKPTIIKVTTTIGFGSLQQGTAGVHGSALKADDVKQLKKRWGFDPNKSFVVPQEVYDYYKKTVVEPGQKLNEEWDRMFEEYKTKFPEKGKELQRRLNGELPEGWEKHLPKFTPDDDALATRKTSQQVLTNMVQVLPELIGGSADLTPSNLTRWEGAVDFQPPITQLGNYAGRYIRYGVREHGMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLAALSGNPVIWVATHDSIGLGEDGPTHQPIETLAHLRAIPNMHVWRPADGNETSAAYYSAIKSGRTPSVVALSRQNLPQLEHSSFEKALKGGYVIHDVENPDIILVSTGSEVSISIDAAKKLYDTKKIKARVVSLPDFYTFDR-------QSEEYRFSVLPDGVP---IMSFEVLATSSWGKYAHQSFGLDEFGRSGKGPEIYKLFDFTADGVASRAEKTINYYKGKQLLSPMGRAF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23254-1", "uniprot_id": "TKT1_YEAST", "id": "P23254-1", "name": "Transketolase 1", "aln": "----------------MTQFTDIDKLAVSTIRILAVDTVSKANSGHPGAPLGMAPAAHVLWS-QMRMNPTNPDWINRDRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDGATSISFDEDVAKR-YEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPTLIKMTTTIGYGSLHAGSHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNKWNKLFSEYQKKFPELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETVLEDVYNQLPELIGGSADLTPSNLTRWKEALDFQPPSSGSGNYSGRYIRYGIREHAMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVGEDGPTHQPIETLAHFRSLPNIQVWRPADGNEVSAAYKNSLESKHTPSIIALSRQNLPQLEGSSIESASKGGYVLQDVANPDIILVATGSEVSLSVEAAKTL-AAKNIKARVVSLPDFFTFDK-------QPLEYRLSVLPDNVP---IMSVEVLATTCWGKYAHQSFGIDRFGASGKAPEVFKFFGFTPEGVAERAQKTIAFYKGDKLISPLKKAF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. :*: : . : :.: . : *:: :* : . . ** :*:: :.: :* ***:. . *** . : : . .: .:.* ** *: :*.: *.** .::* * : . : : :*:*::. :: . :: :. .: * : *** : * :. : . : :.: . . : . : . * .. ::.: .* .: .:: ..* .. : . *:*. :: : : * : : :: *.: * . :*:..:: : . * . . *:*.. : :* :* :*::* :: *:*. ... * : : : . : : . : . . *::. . .: ::.:* : .: ** * . * **:. . .:* : *. .: * : * : . : : : . ** .: ..:. : : ", "identical_positions": 63, "similar_positions": 186, "identity": "8.89%" }, { "cls_id": "homologset.agr.MGI:1933247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5S1-1", "uniprot_id": "D4A5S1_RAT", "id": "D4A5S1-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MDPVLIHAQVQLWSAKAGMSKSRNAFIETFIGKREVKLILYFSTGKIKALQLYNNIKSVVLRTYGEDQNYLHLTFKNNDFLFVEKLTTMDARRLKRFLDKIYQSNLR-AARRSGERPGDPSTSAQELSSSPP-EGHLKASSACFESAKESEMCLFRQLPLLPPSSASLNAVGLLESQFMKRKRFFLGAEK-EKQ-NLKGSTREFETN---LVVSISNEKGKERGVRAVEISKAGFGFPFETNYPEEGS-----VNVRDLNDLITKLFSPLLFETHYIENGLDWHEYMETFLLDPEKSWQGLPNVGNTCYINVVLQSLCSIPLFVNDLFNQGFPWIKPPKDDFNMRLMQLLVLKDIYNARTRQKLLIGITKALPIFGEVFAADRQNDAHEFLSLCLVQLKETVQRVNMMWQSENESGDYYLLREIFANYTSINRTPVCPVTNNFEFELLSSIFCKACGLTVFKREPSRYLSINIPQGMKDQNMSIQSSLDLFFRAEELEHRCERCLYNKSVALHKFGRLPRVIIVHLKRYSFSESRIMNKDEQHIVISKYLRLSCHCNKNTKPPQPLLPNEHVKNLDLLRPLEELGSEILKLSSNSGRTSRSKVFPTVNIRSDKELEVQNGKRVSEVSSGSAQQEDPGKG--ANVVRSELTNETETIK-HEKEYVLSDLDSGS--------------------------------------------------------------ISEERSQKCQEAEKCNK---------EALPQSCPKPSSQEQTENLGKPAVSHTQNGSLSSQGSSDSSKSPGCNDVFDK-AKPTSKVEPQKLNQKEDNIYRLVSIINHIGNSPNGGHYINDAFDFRKQSWFTYSDLQVTGIQEDLVYKARLSTGYVFFYMHNDIFEELLAKEAWSTSTSKG--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MX1-1", "uniprot_id": "UBP26_MOUSE", "id": "Q99MX1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 26", "aln": "MEPILINAQVQMWSAKAGMSKSRNALIETCVGKREVKLILYFSTGKIKTLQLHDNIKSVVLQTYGEDQNYLHLTFKNNDFLFVEKLTTTDARRLKRFLDKTSQGSIR-PAR-SDERCGEPSTSAQELNGS---GSSCETNSECFESPKESEMCMFRELSLLPSSSTFLHNVGLLENQFIKRKRFFSDLAKNEKQSNLKDSIRDFEAN---LVVCISNEKGKERNVREVDISKPGFGFPFETNYPEDSG-----VDVRDLNDLITKLFSPVLLETHCIENGLEWHEYMKTYLLYPEKLWQGLPNVGNTCYINVVLQSLCSIPLFINDLFNQGFPWIKAPKDDFNMLLMQLLVLKDIYNARFRQKLLIGITKALPIFGEIFAVDRQNDAHEFLSLCLVQLKETFQRVTMMWQSENDSGDFYLLKDIFADYATINKMPVCPVTNNFEFELLSSIFCKACGLTLFKGEPSRYLSINIPQGGKD--MSIQSTLDLFFSAEELEHRCEKCLYNKSVSFHRFGRLPRVIIVHLKRYHFNESWVMKKDERPILVSKYLRLSCHCSKSTKPPPPLRPGEHVKNLDLLKPLEVLGSEILKLPFNSVRTSRSKGFETINITSNRESEAQSGKRVSEVLSGKVQQENSGKGDTAHIVGSELTKETEKLKKHEEEHRPSDLDSGS--------------------------------------------------------------IREA--QKYQQAEKCNEGRSDKQISLEALTQSRPKPISQEQTENLGKTTLSHTQDSSQSSQSSSDSSKSSRCSDDLDKKAKPTRKVDPTKLNKKEDNVYRLVNIINHIGNSPNGGHYINDAFDFKRQSWFTYSDLHVTRTQEDFVYRGRSSTGYVFFYMHNDIFEELLAKETQSTSTSKG--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXU7-1", "uniprot_id": "UBP26_HUMAN", "id": "Q9BXU7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 26", "aln": "MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVVLKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGKGGSVFSSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLT-SKLTLTCGELSENQHKKRKRMLSSSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKK---LECESSCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFS-CPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWP--ATKESKDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPLAHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKFVAFDRIINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNLLRPTKLNLQKSNRNSLLALGSNKNPRNKDILDK--IKSKAKETKRNDDKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFEEMLKREENAQLNSKEVEETLQKE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:::.. **: ..*:*:***::*:**: *:: :*:***.:** .:::* :**:.***::* :**:****::**: **:* *:: **.:** ***: *..:: ..* . .**: :*:. : ::.* .** .* * :::.:.**. *. * * *.*. ****:: . : ::: :.. ::: . .:* :: *: :: :: .* : *:. :. :: *: * *:. .*:: :. .*.: : * *** :****:*****:*.***** *** * :**:**.*** * * : :.* * :**.:** ** . :: **:.:.**:. .*:* : ********: ** ***:..:::. :*:.:.: *: : :::**: . . . *** .***:*** ** ***** .::* * ..*****:** * ****::**** *****::* :* ::.**..* *.****::******* :.* ::*::: :::****::*.**.:.*:** ** . .:.:::**: :. : * :.:. *..** : : :* *::* * :.*: * : * **: **. .: : * : : :: . : : *:. * * * : :::::*: :**.** *** :* :*:** :.: : *... .* : .*.*.. .* :** : :. : :.* *: ***:.::.*:*:: :.**** **:**.:* ****.*::* ** : . * .***:******:****:* :* : .** ", "identical_positions": 290, "similar_positions": 297, "identity": "31.45%" }, { "cls_id": "homologset.agr.MGI:1933250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RA42-1", "uniprot_id": "M0RA42_RAT", "id": "M0RA42-1", "name": "Protein unc-93 homolog A", "aln": "-------------------------------------------------------------------------MERSMKNVLVVACGFLLLFTAYGGLQNLQSSLYSAHGLGVATLSTLYGSVLLSSMFLPPILIKKCGCKWTIVGSMCCYVVFSLGNFHANWYTLIPTSILLGLGAAPLWSAQCTYLTVIGNLQAEKVGKLGKDVVN--QYFGIFFLIFQSSGVWGNLISSLVF------GKMSMQDAIPDEQ---------LMSCGAKDCL-MGPSATNTTHHPSQQLIYTLLGIYTSSGVLAILLVAVFLEPV-KDK-LENEGETRSRP--LWSTLLSTFMLFRDKRLCLLMFLPVYSGFQQGFLSGEYTKSYVTCALGIRFVGYVMICFSAMTALCSLLYGKISKYTGRITLYVLGAAIHFSCIVVFLLWHPNPAQLPVFFVLSGLWGMADAVWQTQNNVLFGVLFEENKEPAFANYRLGEAVGFVIAFGYSSFLCVSTKLYILLGVLSVAMVSYGTVEYREYKAAS--------KVLAAEEK-----------------------------NQAEEEGTKM---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q710D3-1", "uniprot_id": "UN93A_MOUSE", "id": "Q710D3-1", "name": "N-acetylglucosamine transporter UNC93A", "aln": "-------------------------------------------------------------------------MERSLKNVLVVSCGFLLLFTAYGGLQNLQSSLYSEQGLGVATLSTLYASVLLSSMFLPPILIKKCGCKWTIVGSMCCYVVFSLGNFHANWYTLIPTSILLGLGAAPLWSAQGTYLTTMGNLQAEKVGKLGKDVVN--QYFGIFFLVFQSSGVWGNLISSLVF------GKMSMQEAIPEEQ---------LMSCGAKDCL-MGPAATNSTHHPSQQLIYTLLGIYTGCGVLAILLVAVFLESL-EDK-LENEGERRPRPPPLWSTLLSTFMLFRDKRLCLLMFLPLYSGFQQEFLSGEYTKSYVTCALGIHFVGYVMICFSAMTALCSLLYGKISKYTGRAALYALGAAIHFSCIVVFLLWHPNTNQLPVFFVLSGLWGMSDAVWQTQNNALFGVLFEENKEPAFANYRLGEAIGFVIAFGYSSFLCVSTKLYILLGVLSLAMVGYGTVEYLEVKAAS--------KVLGAEKK-----------------------------NQAEEEEMKTKI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WB7-1", "uniprot_id": "UN93A_HUMAN", "id": "Q86WB7-1", "name": "N-acetylglucosamine transporter UNC93A", "aln": "-------------------------------------------------------------------------MDRSLRNVLVVSFGFLLLFTAYGGLQSLQSSLYSEEGLGVTALSTLYGGMLLSSMFLPPLLIERLGCKGTIILSMCGYVAFSVGNFFASWYTLIPTSILLGLGAAPLWSAQCTYLTITGNTHAEKAGKRGKDMVN--QYFGIFFLIFQSSGVWGNLISSLVF------GQTPSQETLPEEQ---------LTSCGASDCL-MATTTTNSTQRPSQQLVYTLLGIYTGSGVLAVLMIAAFLQPI-RDVQRESEGEKKSVP--FWSTLLSTFKLYRDKRLCLLILLPLYSGLQQGFLSSEYTRSYVTCTLGIQFVGYVMICFSATDALCSVLYGKVSQYTGRAVLYVLGAVTHVSCMIALLLWRPRADHLAVFFVFSGLWGVADAVWQTQNNALYGVLFEKSKEAAFANYRLWEALGFVIAFGYSMFLCVHVKLYILLGVLSLTMVAYGLVECVESKNPI--------RPHAPGQV-----------------------------NQAEDEEIQTKM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPF7-1", "uniprot_id": "UN93A_DANRE", "id": "Q5SPF7-1", "name": "N-acetylglucosamine transporter UNC93A", "aln": "-------------------------------------------------------------------------MSRNTKNVLVVSFGFLLLFTAYGGLQSLQSSLNAEEGMGVISLSVIYAAIILSSMFLPPIMIKNLGCKWTIVVSMGCYVAYSFGNLAPGWASLMSTSAILGMGGSPLWSAKCTYLTISGNRQGQKHNKKGQDLIN--QYFGIFFFIFQSSGVWGNLMSSLIF------GQD--QNIVPKEN---------LEFCGVSTCL-DNFTVIGNSTRPSKHLVDTLLGCYIGVGLLAIIFVAVFLDNIDRDEAKEFRSTKGNKS--FWDTFLATFKLLRDPRLLLLIPLTMYSGFEQSFLSGEYTKNYVTCALGIHNVGFVMICFAASNSLCSFAFGRLAQYTGRIALFCLAAAINLGSFLGLLYWKPHPDQLAIFFVFPALWGMADAVWQTQTNALYGILFAKNKEAAFANYRMWESLGFVIAFAYSTFICLSTKIYIALAVLALTMVTYLYVEYNEYKHPTPQVTEDFLKPIKPKLK-----------------------------DDKEDNIISQTQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y115-1", "uniprot_id": "UN93L_DROME", "id": "Q9Y115-1", "name": "UNC93-like protein", "aln": "-----------------------------------MTGFTNAGFENDEPVKPKAGFEPDTASLREKVVLNPGEKWRILKNISIISIAFMVQFTAFQGTANLQSSINAKDGLGTVSLSAIYAALVVSCIFLPTLIIRKLTVKWTLVCSMLCYAPYIAFQLFPRFYTLVPAGILVGMGAAPMWASKATYLTQVGQVYAKITEQAVDAIIV--RFFGFFFLAWQSAELWGNLISSLVLSSGAHGGGSSSNTTVSEED---------LQFCGANFCT-TGSGGHGNLERPPEDEIFEISMIYLSCIVAAVCIIAFFLDPLKRYG-EKRKGSNSAAELSGLQLLSATFRQMKKPNLQLLIPITVFIGMEQAFIGADFTQAYVACALGVNKIGFVMICFGVVNALCSILFGSVMKYIGRTPIIVLGAVVHFTLITVELFWRPNPDNPIIFYAMSGLWGVGDAVWQTQINGLYGLLFRRNKEAAFSNYRLWESAGFVIAYAYATTLCTQMKLYILLAVLTLGCIGYVIVEILYRKKQRKLKKQE--KLEAAEKEKEAAAAAAAAALAAAEAGADGVEETDDELDDLEEDIVVTRL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZU1-1", "uniprot_id": "B7YZU1_DROME", "id": "B7YZU1-1", "name": "UNC93-like protein", "aln": "MNQWGLLTPDPELDMVYPSDTSDANNEELALEHSVAHGNVHGNGTGTGGSSPGTTTAPNGDNKVNQRHYEPAERFIITKNVVVIGLAFMIHFTAFHGTSNLQSSVNADKALGTTTLAVIYGSLILSNIFLPMTVIRWFGCRLTMALALFAYMPYIAAQFYPRFETLIPAALMVGFGGGPLWCSKCTYLSTVSEALTQVRGNKSRKDVNTVKFFGLFFIFYQMAQVWGNLISSSVLTLSAPAAQSAANDSFELEVQRELERNRVAELCGARFCPGVGAEANPNLVPPAPEQIQLLNSIFLTCMAAAVVMMIFGVSSLKRYGVKRGDTGDGMSG---LKLLTVTINLLRKRRQILMLPITMFIGLEEAFLAVDFTRSFVACGWGISRIGFAMICFGVANAVAAGIAGALVERIGRVTLAALCAVVNLCLLTYMYTWEAREGDYMSYCTFAAVWGICDGVWLVVVNAFYGILFPNHLIAAYSNFRLWESTGSVIGYVISSQLCTSTKLVILIIFILVGCVGYGLIEYRFWQKQK------------------------------------------------NLEVMLSD--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: ::. .*:: ***: * .****: : ..:*. :*:.:*..:::* :*** :*. : *: :: * : :: . : :*:.:. ::*:*..*:*.:: ***: .: : : : ::**:**: :* : :****:** :: . : . * **. * . *. . : : : *: :: :. : . . . : *: :. . *:: :.:: *::: *:. ::*: :*:* *: :*:.****.. ::.: * : : ** : * *. :. : *... . : .:..:**: *.** . * ::*:** . .*::*:*: *: * **.: : :* *: * : .: : : * :* : : : ", "identical_positions": 85, "similar_positions": 161, "identity": "14.43%" }, { "cls_id": "homologset.agr.MGI:1933277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08949-1", "uniprot_id": "TF2AA_RAT", "id": "O08949-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHH-HQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASSITSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQIPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52655-1", "uniprot_id": "TF2AA_HUMAN", "id": "P52655-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHH-HQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMS-AAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99PM3-1", "uniprot_id": "TF2AA_MOUSE", "id": "Q99PM3-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHQHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLLQHMNASSITSAAATAATLALPAGVTPVQQLLTNSGQLLQVVRAANGAQYILQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPAPAQAPMPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52654-1", "uniprot_id": "TF2AA_DROME", "id": "P52654-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "--MALCQTSVLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVELSPDSG-------DGSHPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVGLKSSAGMAAGSGIRNGLVPIKQEVNSQNPPPLHPTSAASMMQ-KQQQAASSGQGSIPIVATLDPNRIMPVNITLPSPAGSASSESRVLTIQVPASALQENQLTQILTAHLIS--SIMSLPTTLASSVLQQHVNAALSSANHQKTLAAAKQLDGALDSSDEDESEESDDNIDNDDDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32773-1", "uniprot_id": "TOA1_YEAST", "id": "P32773-1", "name": "Transcription initiation factor IIA large subunit", "aln": "----MSNAEASRVYEIIVESVVNEVREDFENAGIDEQTLQDLKNIWQKKLTETKVTTFS----------------WDNQFNEGNINGVQNDLNFNLATPGVNSSEFNIKEEN--------TGNEGLILPNINSNNNIPHSGETNIN-----TNTVEATNNSGATLNTNTSGN--------------------------------------TNADVTSQPKIEVKPEIELTINNANITTVENIDDESEKKDDEEKEEDVEKTRKEKEQIEQVKLQAKKEKRSALLDTDEVGSELDDSDDDYLISEGEEDGPDE----------------------NLMLCLYDKVTRTKARWKCSLKDGVVTINRNDYTFQKAQVEAEWV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*. ::*.*:.:**: * : *:***.* ::* :*.:** ::.. :. : : : : .. . :.. * .. . : . . .. . . :. :.: .. : : * .: : . : . : . :: .: **. :. .:. .:. * *:::* ***: *:: :** ****::.:. .** *.*: :*** ", "identical_positions": 39, "similar_positions": 91, "identity": "10.29%" }, { "cls_id": "homologset.agr.MGI:1933281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70608-1", "uniprot_id": "SYCP2_RAT", "id": "O70608-1", "name": "Synaptonemal complex protein 2", "aln": "MPVRPDPQQLEKCIDDALRKNDFKPLVTLLQIDICEDVKIKCSKQFLRKLDDLICRELHKKDIQTISNILISIGRCSKNIFILGQTGLQTMIKQGLVQKMVSWFENSKEIILSQRQSKDEAVMNMIEDLFDLLMVVYDVNDEGKNQVLESFIPHICALVIDSRVNFCIQQEALKKMNLMLDRIPQDANKILCNQEILTLMSNMGERILDVGDYELQVGIVEALCRMTTEKRRQELAYEWFSMDFIANAFKKIKDCEFETDCRIFLNLVNGMLGDRRRVFTFPCLSAFLGKYELQIPSDEKLEEFWIDFNLGSHTLSFYIAGDDDDHQWEAVTVPEEKVDMYNIEVRESKKLLTLTLKNIVKISKKEGKELLLYFDAALEITNVTKKLFGGNKYKEFTRKQDISVAKTSIHVLFDASGSQILVPESQPSPVKENLIHLKEKSNLQKKLTNPLEPDNSSSQRDRKNSQDEITTPSRKKMSEASMIVPDTDRYTVRSPILLINTSTP---RRSRAPLQAIHSAEK-AVSKTSESGVDYAVSLKSRQSDGRNRGNNRANHNKT-ATVQNKGHEHHESPDQTFNEIEETLSDAY-AVEKVDKPVLPGVLD-ISKNKAHSRWACWTPVTTIKLCNNQRSCALPGDTFTQDTGVNKKCTKQKS---VSDDDSEETQRVKYSKDVIKCNKSE--EAEVCERNIQEQNHPKYSQKKNTANAKKNDWHIESETTYKSVLLNKTTEESLIYKKTCVLSKDVNTTICDKSPSR-KSMRSHTKSRKELMSEVTSCELDEIPVRENSKGKRFTGTAESLINLINKRYNSSDDMISTRKLKEPRDGSGFSKKPELQFN--KVQRKSYRKLK-TVVNVTSECPLNDVYNFSLNGADEPVIKLGIQEFQATTREASMDNSIKLVDVRNRDERDLSLKTKDERILS-HERKTLFSDTETECGWDDSKTDISWLRKPKSK-RLMDYSRNKNTKKCKSIKSRSSTEKGQPRSTVVLSKNIAKNDYEVIVDGRTRLPRRATKTKKNYKDLSTSGSESESEKEISYLFKDKLPTKEETVHSSAQTKKLPKKQQKVFNTEALKGQPSEEQKNSSTLRNG-REDSLYLSSASVSGSSSSVEVMRCTEKITERDFTQDYDYITKSLSPYPKAASPEFLNRSNRVVGHGKSPRISETSAVCVRKSCSPASGLPFSPRHT-TKNNSVMNIKNTNSVINNQRTQHCNSYSDVSSNSSEKLYMEPESPDSCENHVQSKREENHAASPFSLSSEKIEKIWFDMPNDNTHVSGPSQRGSKRRMYLEEDELSNPSEAEVQEAEER-EHLVSKKLCQREHFDQHTSET-----SLSTPEFSVP-KDWQQELQGAGMFYDN---INSDYKRKTDTQHKIMDDFTTKTLKLTQQHLLAMACQARGHRDENIDKFQVTLLDELEKVEKDSQTLRDLEKEFVDIEEKIVHKMRAFHQSERERFRALKTSLDKSLLVYNSVYEENVLTSEMCLMKANMKMLQDKLLKEMHEEELLNIRRGLESLFKDHEGNNA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CUU3-1", "uniprot_id": "SYCP2_MOUSE", "id": "Q9CUU3-1", "name": "Synaptonemal complex protein 2", "aln": "MPVRPDLQQLEKCIDDALRKNDFKPLLALLQIDICEDVKIKCSKQFLRKLDDLICRELNKKDIQTVSSILISIGRCSKNIFILGQAGLQTMIKQGLVQKMVSWFENSKEIILNQQQSKDEAVMNMIEDLFDLLMVIYDISDEGKNQVLESFIPQICALVIDSRVNFCIQQEALKKMNLMLDRIPQDANKILSNQEMLTLMSNMGERILDVGDYELQVGIVEALCRMTTEKRRQELAYEWFSMDFIANAFKEIKDCEFETDCRIFLNLVNGILGDKRRVYTFPCLSAFLGKYELQIPSDEKLEEFWIDFNLGSHTLSFYIAGDEEDHQWEAVTVPEEKVQMYNIEVRESKKLLTLTLKNIVKISKKEGKELLFYFDESLEITNVTKKVFGGNKYKEFTRKQGISVAKTSIHVLFDASGSQILVPESQPSPVKENLIHLKEKSDIQKKLVNPLELGNSSSQ-------DEITTPSRKKMSEASMIVPDTDRYTVRSPILLINTSTP---RRSREPLQAINSVEK-AVSKTSESGMDYAASPKSRQSDGRKRWNNRANHNKTTAVIQNKQYEDNESPDQNFNEIEDTLSNVSSAVGKVDKPVLPGVLD-ISKNTTHSRWACWTPVTTIKLCNNQRSRALPGDTCTQDTGVNKKCTKQKS---VSDDDSEETQKGKYSKDVIKCNKSD--EAEFCERNIQEQNHPKYSQKKNTANAKKSDWHIESETTYKSVLLNKTTEESLIYKKTCVLSKDVNTTICDKSPSR-KSKRNHTKSRKELMSELTSCELEEIPVRENSKGKRFTGASESLINQISRRYNPSDSMMSTRKLKEPQDGSGFSKKPDLQFN--KVQRKSYRKLKATVVNVTSECPLDDVYNFSLNGADEPVIKLGIQEFQATTREASMDNSLKLV--KNHDEHDPFLKTKDKRMLS-YEKKTLLSDTETECGCDDSKTDISWLKEPKTK-RLMDYSRNKNTTKYKSRKSRSSMEKGQPRPTMVLNKNSMKNDYEVVVDGRTRLPRRATKTKKNYKDLSTSESESESEKECSYLFKDKLPTKEETIHSRAQTKKLPEKQQKVFNSEALKGQPSEEQKNSSRLREG-REDSLCLSSASVSRSSSSVEVMRCTEKITERDFTQDYDYITKSLSPYPKAPSPEFLNGNNSVVGRGQSPRISETSAMCVRKSYSPASGPPFSPRHTPTKNNSVVNMKKANSVINNQRTQHCNSYSDVSSNSSEKLYMEPESPESCDNHMQNKREGNHAASPLSLSSEKIEKMWFDMPSENTHVSGPSQRGSKRRMYLEDDELSNSNEAEVEEAEER-EHLLSKKRCQWENSDQHTFKT-----SLSTPDFSVP-KDWQQELQGAGMFYDN---ISSDYKRKTDSQHKIMDDFTTKTLKLTQQHLMAMTSQAQGRRDENVEKFQVTLLDELEKVEKDSQTLRDLEKELVDIEEKLVQKMRAYHRCERERFRVLKTSLDKSFLVYNSVYEESVFTSEMCLMKANMKMLQDKLLKEMHEEEVLNIRRGLQSLFKAHEGNDA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BX26-1", "uniprot_id": "SYCP2_HUMAN", "id": "Q9BX26-1", "name": "Synaptonemal complex protein 2", "aln": "MPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHNVSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDEAVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAMLDKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFIAKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPEEKVQIYSIEVRESKKLLTIILKNTVKISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPESQISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQ-AAEKRDHTILPGVLDNICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSN--SESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEK-ELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYPKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREESHLASSLSKSSEGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDN-LSNSNEVEMEEKGERRANLLPKKLCKIEDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCN-TDSEETVFTSEMCLMKEDMKVLQDRLLKDMLEEELLNVRRELMSVFMSHERNANV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*** ******************* :******************::*:*:******:*:**:.:* **:*:***.*** :***:** *******:****:***:**:** .* :******:******.***:*::*:.****:**:***:*:**:********:***** :**** ***::****.***.***:* ***.*******.***:****************:*****::********:***.***.***************:***:***:*********.***********************:*********::**************::*.***********: *** *****:******:*** :*******:*:**..*::* ***.*******:*:*************** *** *:*: *****. *::.:* : :.*.: * ****::*********..:****:***:*: *** * ** : *** *.** :**:***. :* *.* ***.*:**:* :* :* ** ::*. :. * *:*.*.*:::.:.: *. * *:.:****** *. *. **:********.*:******: : .*** .** :*** ***** :**.:** * : **.*: . * : *.*.*::: *:******* :*** ***:.** :*****:******** ******:*. :*******: ***.** *. :.* *:.*** **:.* : .: :**:****.**..:****. *.:**:..*.: *******. .****:** :*:. ***:******* *.********::*****.*****:*:***********::**. *.*::** :*:** . :****::::: :::*.*:****** **********::**:* :*:*******..: ** ***** ***** ..:. .** *: :.: :** ****:************. ****.*:* *: **:::*.***.:** :* ***:****** :*: * : *:: **** *::. *::.* **. *:* *.**:** ** *****:******* ****:*****:.* * ** .. * * :**: .*.. :*. :* ** . * **** **.*:::* *: .*:: .*.**:.******** ***: :** ***. :*::*.*** .* **.:* *** ** ***** : ******:*: *::*:*:*:: ***..*.*::* ** :*:.** *: *. *:* : **** :**:* : **:*: * * *:. :.*::**:.: :**::. ***:: * :**** :* *::. * ::::***. :::***:.*****:*:*****:**: **:.:*: *:::.*::*:: ***** **.: : **.*:******** :**:***:***:* ***:**:** * *:* ** * ", "identical_positions": 915, "similar_positions": 382, "identity": "59.57%" }, { "cls_id": "homologset.agr.MGI:1933289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZM7-1", "uniprot_id": "T2AG_MOUSE", "id": "Q80ZM7-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08950-1", "uniprot_id": "T2AG_RAT", "id": "O08950-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52657-1", "uniprot_id": "T2AG_HUMAN", "id": "P52657-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINAALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52656-1", "uniprot_id": "T2AG_DROME", "id": "P52656-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MS----YQLYRNTTLGNTLQESLDELIQYGQITPGLAFKVLLQFDKSINNALNQRVKARVTFKAGKLNTYRFCDNVWTLMLN------DVEFREV--------HEIVKVDKVKIVACDGK-SGEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5B9-1", "uniprot_id": "T2AH_DROME", "id": "Q9W5B9-1", "name": "Transcription initiation factor IIA subunit 2-2", "aln": "MN----YQHYRATTLGRTLQDTLDEMMERGDITKKIANLVLLRYDKSISTALKDHGTSNMSFTAERLETFRCCDNVWTLILK------DAEFRED--------QHSLKVDVVKIVACLGTDNGNE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32774-1", "uniprot_id": "T2AG_YEAST", "id": "P32774-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETFDKVVAETLKDNTQSKLTVK-GNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDSQSVISVDKLRIVACNSKKSE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: ** :*:*.:* ::** ::. * :* ** :** : :* :. .:.. *:*: **:***:::: : ..*: :.** ::**** .. . ", "identical_positions": 30, "similar_positions": 38, "identity": "23.44%" }, { "cls_id": "homologset.agr.MGI:1933302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQE3-1", "uniprot_id": "D3ZQE3_RAT", "id": "D3ZQE3-1", "name": "E3 ubiquitin-protein ligase TRIM8", "aln": "MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEKPPTALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQERLEEREQDIEDQLYKLESDKRLVEEKVSQLKEEVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTGSSLSPPKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVNSSGAEKRKHSTAFPEASFLETSSGPVGSQYGAAGPASSEGQSGQPLGPCSSTQHLVALPGGAQPVHSSPVFPPSQYPNGSATQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLSGLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PJ2-1", "uniprot_id": "TRIM8_MOUSE", "id": "Q99PJ2-1", "name": "E3 ubiquitin-protein ligase TRIM8", "aln": "MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEKPPTALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQERLEEREQDIEDQLYKLESDKRLVEEKVSQLKEEVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQRLFDKTEDVGFMKNTKSVKILMDRTQTCTGSSLSPPKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVNSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASSEGQSGQPLGPCSSTQHLVALPGGTQPVHSSPVFPPSQYPNGSTTQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPGLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZR9-1", "uniprot_id": "TRIM8_HUMAN", "id": "Q9BZR9-1", "name": "E3 ubiquitin-protein ligase TRIM8", "aln": "MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVSSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASGEGQSGQPLGPCSSTQHLVALPGGAQPVHSSPVFPPSQYPNGSAAQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPSLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************************************************************:*************************************************************************************************************:***************************.************************************************************* ********.*******************.*****.**********************************************.***************************.******.**.***********************:******************::****************************************************************..*********************************", "identical_positions": 535, "similar_positions": 15, "identity": "97.1%" }, { "cls_id": "homologset.agr.MGI:1933331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACH5-1", "uniprot_id": "D4ACH5_RAT", "id": "D4ACH5-1", "name": "Elongation of very long chain fatty acids protein 4", "aln": "MGLLDSEPGSVLNAVSTAFNDT-VEFYRWTWS-IADKRVEDWPLMQSPWPTLSISTLYLLFVWLGPKWMKDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSYNAGYSYICQSVDYSNDVNEVRIAAALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLVQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYTRTYNEPKKSKTGKTATNGISANGVNKSEKQLVLENGKPQKNGKPKGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQC4-1", "uniprot_id": "ELOV4_MOUSE", "id": "Q9EQC4-1", "name": "Very long chain fatty acid elongase 4", "aln": "MGLLDSEPGSVLNAMSTAFNDT-VEFYRWTWT-IADKRVADWPLMQSPWPTISISTLYLLFVWLGPKWMKDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSYNAGYSYICQSVDYSNDVNEVRIAGALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLVQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYTRTYNEPKQSKTGKTATNGISSNGVNKSEK--ALENGKPQKNGKPKGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZR5-1", "uniprot_id": "ELOV4_HUMAN", "id": "Q9GZR5-1", "name": "Very long chain fatty acid elongase 4", "aln": "MGLLDSEPGSVLNVVSTALNDT-VEFYRWTWS-IADKRVENWPLMQSPWPTLSISTLYLLFVWLGPKWMKDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSYNAGYSYICQSVDYSNNVHEVRIAAALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLIQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYIRTYKEPKKPKAGKTAMNGISANGVSKSEKQLMIENGKKQKNGKAKGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JNR0-1", "uniprot_id": "A8JNR0_DROME", "id": "A8JNR0-1", "name": "Elongation of very long chain fatty acids protein", "aln": "-------------MTSSMGNDTKTESYSYPFADLADERTQDWPLVKSPWNIIALLALYLLMVRYAPKWTARCKPLQLRVPLFCHSLAMIFLNGYICLEFLTASLSLGYNFACQECRVSHDPHEIRIAAAMWWFYISKILEFVDTAFFILRHKWNQLSFLHVYHHSTMFLFCWTYVKWLPTGSTFFPSMINSFVHVIMYSYYALSVLGPRVQRFLWWKRYLTGLQLVQFTIIFFWASQLVFRGCEYGKWLTPIGAAYMVPFLFMFGRFYAQKYCVSAVVKKAK----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *** .* * :.:: :**:*. :***::*** ::: :****:* .*** :*:*:*: *: :.:.*::** :* *:: .* . **.: **. *:: :*:***.*:**:::** :*::**.*****:* **:********.*** : * :**:. *.:** : :***:********.*:.:** :*::******** ***:** : : :: :: .* : **: ** :.*:*:* .** :.* . * .* ", "identical_positions": 116, "similar_positions": 88, "identity": "36.71%" }, { "cls_id": "homologset.agr.MGI:1933365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2R4-1", "uniprot_id": "A0A0G2K2R4_RAT", "id": "A0A0G2K2R4-1", "name": "Synaptotagmin-like protein 1", "aln": "MPQRGHPSQERLRALPSLPMAHGPGPEAEGLLDLSFLTEEEQEAISDVLKRDAHLRQLEEGRVSKLRASLADPWQLKILTGDWFQEARSQRHHHAHFGSDLVRASIRRKK----------SSKGDQALGSDGDGEAAGEDTIE-----------------------------------EAEPRVSIKVAA------------------------------------PETHTETQEPDFSSPY---------------------------------------------------------------------------------------------------------------------------------VLTKVS-SQEEEPQDQEGEREAPGQGG--VQVAEA-------------------------------DPELDPEQEAEQESWPT------------------------------------------------------------------------------------------------------------------------------------------------PAQIKTTSKVLE---------------------------------------------------------------NGEETPGLGPSLDRMLSSSSSVSSLNSSTLS-----GSLKSLSGEA-EAGPVQVRGSVLFSLRYEPGTGELRVQVIQCQGLAAA--RRRRSDPYVKSYLLPD--KQNKRKTSVKKRNLNPIFNETLRHSVQQADLPGRVLSLSVWHRESLGRNIFLGEVEVPLDTWNWD-SEATWLPLQPRIPTSPDELPSRGLLSLSLKYIPAGSEGGGQPPSGELHFWIKEAQGLVPLRPGSLDTYIQCSVLPDDSRASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALASRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQTLLEQPCEWVDGLLPLRTNLVPRA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N80-1", "uniprot_id": "SYTL1_MOUSE", "id": "Q99N80-1", "name": "Synaptotagmin-like protein 1", "aln": "MPQRGHPSQERLWALPSLPMAHGPGSEVEGLLDLSFLTEEEQEAISDVLKRDAHLRQLEEGRVSKLRASLEDPWQLKILTGDWFQEARSQRHHHAHFGSDLVRASIRRKK----------SPKGDQALGSDGEAEAAGEDTIEG----------------------------------EPESRVSIEVAA------------------------------------PERSTETQGPDLSSPY---------------------------------------------------------------------------------------------------------------------------------VPSKASEGQEEEPQDHECELEAPGEGG--VQVAEA-------------------------------DPELDPEQKAEQESQPT------------------------------------------------------------------------------------------------------------------------------------------------PAQSKATSKILE---------------------------------------------------------------NGEEAPGLGPSLDRMLSSSSSVSSLNSSTLS-----GSLMSLSGE--EAGTVQVRGSVLFSLHYEPGTSELRVQVIQCQGLAAA--RRRRSDPYVKSYLLPD--KQSKRKTSVKKRNLNPIFNETLRHSVQQADLPGRVLSLSVWHRESLGRNIFLGEVEVPLDTWNWD-SEATWLPLQPRVPPSPDELPSRGLLSLSLKYVPAGSEGGGQPQSGELHFWVKEAQSLVPLRPGSLDTYIQCSVLPDDSRASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALASRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQTLLERPCEWVDGLLPLRTNLVPRA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYJ3-1", "uniprot_id": "SYTL1_HUMAN", "id": "Q8IYJ3-1", "name": "Synaptotagmin-like protein 1", "aln": "MPQRGHPSQEGLWALPSLPMAHGPKPETEGLLDLSFLTEEEQEAIAGVLQRDARLRQLEEGRVSKLRASVADPGQLKILTGDWFQEARSQRHHNAHFGSDLVRASMRRKK----------STRGDQAPGHDREAEAAVKEKEE-----------------------------------GPEPRLTIDEAP------------------------------------QERLRETEGPDFPSPS---------------------------------------------------------------------------------------------------------------------------------VPLKAS-----DPEEASQAQEDPGQGDQQVCAEEA-------------------------------DPELEPASGGEQEPRPQ------------------------------------------------------------------------------------------------------------------------------------------------QAQTKAASQILE---------------------------------------------------------------NGEEAPGPDPSLDRMLSSSSSVSSLNSSTLS-----GSQMSLSGD---AEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAA--RRRRSDPYVKSYLLPD--KQSKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWG-SEPTWLPLQPRVPPSPDDLPSRGLLALSLKYVPAGSEGAGLPPSGELHFWVKEARDLLPLRAGSLDTYVQCFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALANRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQALLEQPCEWVDGLLPLRTNLAPRT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8P2-1", "uniprot_id": "Q1L8P2_DANRE", "id": "Q1L8P2-1", "name": "Synaptotagmin-like protein 1", "aln": "-------------------------MEKEPVLDLCHLTEVEQTVILNVLLRDAELRSREEGRVRKLQQTVSDPVHLRSLSGAWFHEERSKRYEKG--GADVVHASLRRKR----------RGK-DLPLTAIFDKGNNSSHVHE-----------------------------------QQEEDRNAERDL------------------------------------QGNMNEREDDKHQEQK---------------------------------------------------------------------------------------------------------------------------------ESGQED-----GESLISNAITIPQSRTRNVTKRNE-------------------------------ILGSGFEDSVEESENKE------------------------------------------------------------------------------------------------------------------------------------------------RRILPSTSPTLQ---------------------------------------------------------------IDSEGDIDSGSTEINYTRFGSVTSLTSHHMMN----GSLMSLYSVG-DFGDVVVSGRIQFSLQYDVRTEELYVHIIRCQDLASA--RKNRSDPYVKVYLLPDNTSRSKKKTAVRRKTLNPVYDETMTYKVRRLDLPARVLSMSVWHMERMRRNLFLGELEVRLGQWDWSQNQPTWQNLQPRVQLSPEAIISRGTILFSIKFVPPGSEGRGNPATGELHIWLREIVGLLPTKRGAPNTYVKSVVLPDESGVSGQQTRVVRGSVSPVFNHTMVYDGFQSSDLIQACAEITVWNP--HPSGCLGGVRLSTGSGLSYGQSVCWMDSTEDEINVWSSVIQSPNSWVDTSLPIRTNLQLCSD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BH78-1", "uniprot_id": "A0A8M2BH78_DANRE", "id": "A0A8M2BH78-1", "name": "Synaptotagmin-like protein 1", "aln": "---------------------MKPSKSALGLLDLSFLSAEEEAAIRQVLLRDEDLKRLESGRVRKLRQSVPDLQQLKNLTGEWFEELRIKRYGQQTDVTAVVRTSMRWKKTAVHKPNPFLNDKLDENKEHDKDEHNTRPNASADPRLIHPALSKETYHQHTHKDFIGDVETPSAPSVSNKKEKLRAETDANPFLNGTDPGHKSTKTQPKELSGGQTTTVFPFSSPVQDTKPERSTTKNPEPRRKVSLPPALQRDQSFEENWVKISLEPNTVKPVHDENNSSGIKLKEVKPHIKNIQDTSSPETSHTESKNVLLKSGSPMKEFHFQPQTSLAFTSHGPELTTHSAHGDSKEVNKFSNAFQNSTSTDQQCLAELTFRESESDKAGPLDSANVRDKGSLASRDIVNDEASSDRKGGEGKNVSIGFLVETDMDQAVEHLTGEEEINKHFSAEEESQSPSLKWGIEMDSHEFPQVKDASSDFGDDVQVQIEKKNENELLYQTTGVKLCDKTVQSDLDSCEDKVKLRSYNNQTLSEISQDIFSMTDDGKLVHIREDKHMDKSVPEPIKPAHPSDDVAGFGQDSSEIKVDVDSAETKSDVLLNVLARAQKTRPPVLQNITNQEPNLEGTDDTVPSIVIVPSESPDPAEMKGNKRGALVLEALLQSSTAKNPSYIADAWEDEGVNSDDDDTSLSSYGSDLSSRKGFSASALSLTDRTGSLLSVYSDAGDFGTVEVQGSVEFAVMYSP-VGELIIMIEQCQDLAIANPRKQRTDPYVKTYLYPDKSRRSKRKTTIKKRTVNPVFVESLRYKVNREELPEKSLNLSVWHNDSRGRNVFLGQVELSFRTWDWGHEALTWYNLQPKTSENAETKESNGLLSVSLKYVPSASTGGSKSSTGEIHVWLREAKELRRLKPQGVDSFVKCYILPDTRKKSRQKTRVVKKTQDPVYNHAMVYDGFKTGEVTEACCELTVWDHNTLANQFLGGVRLSLGTGQSYGKKVDWMDSVDEEVQIWKRMLASPNSWVEGELPLRSAMTPRKSTS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :***..*: *: .* ** ** *: *.*** **: :: * :*: *:* **.* * :*: : : :*::*:* *: : * : . : . * . . . : . : : *:. : . *: . : . * . : .* ..:.: : ** *: . * * * : *:: *. . ** : : :**.** * *:.*:***** ** ** :.*:**:::::.:**:: *:: :.* : :* : *.:**** : **:***::*: : *:*. . ** ***: ..: *.* : .*:*::*..* * . . :**:*.*::* * : . :::::. :*** * *:****: : .**:**:****** ..:: :**.*:::*: .. ***.*** *:* *** .* ****. :* ::*. :: * .**: **:*: : ", "identical_positions": 148, "similar_positions": 159, "identity": "14.35%" }, { "cls_id": "homologset.agr.MGI:1933366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AM63-1", "uniprot_id": "A0A8I6AM63_RAT", "id": "A0A8I6AM63-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQDAILKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHKDKIHGADIIRASMRRKRLPAAAEQKKDTAMRTKESWVNNVNKDASLPPELA-VVEEPADDTGPAGPSSSVVDPASSAIERS---------------------QENTRTPAVSLPKQRKNPFDSLETPEDLSSQQTKTKQSKTGKAGLFQIS----KEGGLSESKEKPSIPDMSCQKSEKPKQ------------PVSMETENASLIKAPIPKARKLIYKSND---------------------LKNDDYLSFAGQRRDSLNARGTPRGILKRNSSSSSTDSET-----------LRLNYNLDPKSKILSPG------------------------------LTIHERISEKEHSLDDDSCTNSLEPLKHVRFSAVKNDLPQSPRPVLGQEVGEFTVLESDRLQNGTEDTGDIDEFQDHPEFS-HRKPLSLYQSVTNPRISERETEQPMSSGSIPSE------------EISCHSDILPTRPQCVE-----SSSIIS-EQDKSSHFTKLQSEMSKSPEDELTQCVEP--------------------EPSQTSDHSFRDHRQGKPLLTALTDQTASPVGPCATEIRKTTDDSISKVLDWFNRS---SHTEDSTSTLQHLQGLDLREQTDSRAQISNTLMTDNMSLKGDDTKVPASTTTKVKPVRPDSTFQEEGDVLASESCRDSDALLKSNSEDLSQQGTLKKGPDTLQRFERYRIPSHKNENMGDSQGSESTGEGVGTLPADSDYLLRPLKRSDSEEAPWNTTHPSSLGKGKTKFHVPQKSKRNTHINADSSVIFLDSILKDDAERKSKTRNISFLKPSLETENSGLPPGATDSGSSWRKPEDQEEVGEEPKNQVLREKYKRVSDRISFWEGGKAGAKLKAPQPASSCSQESSSTKAYQPVKSQVMSLGSLSLGQSDYSQVTAKHGVFDGDDQTPRLASSSSSNKPETTGSPISGLSKNHPSGNQFGKVTLPQTMENETHPSLEKDRFLIDKSNGNFKVLSLRERMDERNTEHVYSHSQFENLRKFWGLGADGNSKHSDGNNTATNKQTSVPSNRQKSKEFNTVNLSSEKTPEVEEGRHLRQGNVGAAEEMEKLNLKCRLPAPPDETKFPQKTPQKFTYPLVGNEPSKEDVGKNTECLVTPVTEKACSDQEIQESIVKTSVLPKVSTDTFKDRVQKLVAEATSPAGQTSGKEVHEQQALKVGASENGAWPQNKSFVKDEEELTGVKKSTKELQRRIPQDCSVDKLLKEATGTPSSPLQSLQEPVMTRPSSPPKEDLLFKKWIRENHSPSADQRERTAPSPQGVETLAGTDFTSKAKHCNTEGMLQLTAEGSPPLAQPSQSFEGVSSPPADVSLSWNAPLLSQDSTLSSQREISEAIEKVVLPSKPAMTDINAVLQKLLREAGEVDTKLPERPLSPQRVSSVWAAPDPVGPNEDSHSSYPVPDTTHEGRSARMAPSAHATTSPTYTVTRYGQELLQEVAETVRETIIQPKPECPEFRAALEKLRKETLQTSLSKDDKNTVTISPSALTGSCETSHQLAFEFHPTEIQETVEKAEAPSVTESIFDVGLEKLLKEMSEGPRQLQLTRDILEKQTSQAEQAGLMGETPHPFLDDSGASKMNFASSGLESQVSPCDKQLGGDEAVTGQLIDVQGYAGGFGVSECPQPYEDHKREDVETVLFVEDKGREKVIAEATRAPQKPGFEEAPKEMRVSRNKRSIVLLETKGKATETSTVKSELATAYKRQEKEQGPEACSESEFSDGNTSSNRESWRNTSSSEEEHSPVLKTLERRAARKIPS-KSLEDIPSDSSNQAKVDNLPEELVRSAEDDQKADQDPDTNECIPGISTVPSLPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRYKKSPSSLTNLSSSSGMTSLSSASGSVMSVYSGDFGNLEVKGSVQFAIDYVESLKELHVFVAQCKDLAAADAKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQVLKTQKLNLSVWHRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYP---LKRKTAPVALETENRGEMKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTSNPVFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEAALWEKMVNSPNTWVEAMLPLRMLLIAKISK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N50-1", "uniprot_id": "SYTL2_MOUSE", "id": "Q99N50-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQDAILKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRRKKLPAAAEQNKDTAMRAKESWVNNVNKDAVLPPEIA-VVEEPEDDTDPAGPSSSLVDPASSVIDMS---------------------QESTRTPAVSLPKQRKNPFNSPKLPEDHSLQQTKPEQSKTGKAGLFQIS----KEGELSESKEKSSIPDMPRQQLEKPKQ------------TVSTEPENASHTKAPIPKARKLIYKSND---------------------LEKDDNQSFPRQRRDSLNARGAPRGILKRNSSSSSTDSET-----------LRLNYNLDPKSKILSPG------------------------------LTIHERISEKEFSLEDDSSTSSLEPLKHVRFSAVKNELPQSPRPVLGQEVGEFTVLESDQLQNGTEDAGDIEEFQNHPELS-HKTPLSHYQLVSSPSDSGREREQLMSSGSAPRD------------EIPCHSDILPTGPQCVE-----SSSVINGQQEKSSHFTKLPSELSKSPSDELTQCGEP--------------------EPSQTADHSFRDHRQG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEEEHSPVLKTLERRAARKLPS-KSLEDIPSDSSNQAKVDNLPEELVRSAEDDQKADQEPDTNECIPGISTVPSLPDNQFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRYKKSPSSLTNLSSSSGMTSLSSASGSVMSVYSGDFGNLEVKGSVQFALDYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQFLKTQKLNLSVWHRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYP---LKRKTAPVALETENRGEMKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPVFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWVEATLPLRMLLIAKLSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCH5-1", "uniprot_id": "SYTL2_HUMAN", "id": "Q9HCH5-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSVIDMS---------------------QENTRKPNVS-PEKRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTS----KEDELSESKEKSTVADTSIQKLEKSKQ------------TLPG-LSNGSQIKAPIPKARKMIYKSTD---------------------LNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSET-----------LRYNHNFEPKSKIVSPG------------------------------LTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPIN------------GLHSHSEVLTARPQSME-----NSPTINEPKDKSSELTRLESVLPRSPADELSHCVEP--------------------EPSQVPGGSSRDRQQG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEEEPSPVLKTLERSAARKMPS-KSLEDISSDSSNQAKVDNQPEELVRSAED----------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYP---LKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6D8-1", "uniprot_id": "A0A8M3B6D8_DANRE", "id": "A0A8M3B6D8-1", "name": "", "aln": "MIDLSHLTEDEQEMILEVLKRDAELKKSDEQRIKQLRKTERDRGRLKYLTGEWFYETKYHRHRDRIHGSDIIRASMKRKPVTLLEITQRWSE---KPSSVYGPKRDVYIPPELSGLIEDPQSHNDRVDDESQQETQRPQVKPRQNPFNIFR-------------LQRDEVKPINAVKEAKQTPAEEPFLPVESYTLHHTTLNTDNTDTHIITLKPVPKKRLLLYSSKDSSLDTANSDNGVKQVVN------------PAPRGILKHNGSSYSSTDSLRLHIPSND---------------------GSSSGQSSATVSPISLETPISPPLSPCSLHSASGWLDRKQ-----------VRFSSIIGPIERVQGEHSLLEEDWS---------------------PLSDQERSCIIENGHHEPQSSQVSNIHTSTEEAGKTTELSTEVKTDKVTVEEDRSILKVFDWFGKGSRDGKLKELPTKKELN-EEEPKPDESLVTKSDDSEAPDVHLKTTKPVPKPR-------RGLFAMFSRAENKDKNPEVQA-----SEKAKCETEANDNILEQISFPTENRMAEILQDENKPDKL---------------CEEPSQQERFDQDEVSTGRLVNLKSFWERGDRGPKILSMKKEDEEEESETSQLNENYH---NTTQSDMLSDSSTSLSKPKLSDPEPADVESTLIGSSLISPRRTSNGVAISLLEDEEPFILDNHKASENSSSKLHTLVEYNALDSDQQEESICRDISDLKKEISTLKISISQHEDKVSINDLKSFWEKEKGGLRVIVSSQTCTANVKDPSPEPSPNRSLGRLSEPQFDIRSNNPSSPDRRIFKEFNLIEQKLKMEKVEDKQRSENTVPLQDLQDIRGRVPHIMQNLSNIEQFIADPHSSPSPPSSPLRSLSPKGQHDKPHYADIYQPKDRDQTRTPSPLRQFKVPCRDSYPSKESTKDGSPLKTFPIDINPANTSSCSVRLKPGQTSMYTSPEHRRKTSDGGSDTRSILTK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERKLSLDSLTRFYIPLSLHHYLGLPKKAALKETEQVKAQAGEMFEQVHQGGVSNESSPSRHSLLESEEITFDSSGSSTPEAWSISHASSYWDSEDDGPFKAALERANARPISISKSLEDLASTPSQERWKTDPRNDVRMSMEN----------------VSAVPPNTKTSFSDPEQVKMMSLSVPALMQQEMECRNSDCASVSSFYNDRQR-SCNTPSNFSTCSEVASMSSVTGSVMSIYSSEFGYVEVKGTVQFAIHYVQKLGEFHIFVVQCKDLAVADVKRNRSDPYVKCYLLPDKAKYGKKKTCVRKKTLDPTYNEILRFKIPMEMLKTQKLNISVWHNDTFGRNSFLGEVEVDLAEWDFNNTQMNEYLLKGRVQIPTSPKHSFGGEEMSAEIKVALRFLPQTTLSHKNKGNGEVQIWVKECKNLPISRGVAIDPFVKCAILPENNRKSRQKTRVLKRAPNPVFNHTMVYDGFGHDDLKDICVELTVWDHDRLNNHFIGGIRLGPGTGKSYGSEVNWMDSNVAEAALWERMVQTQNEWVEDTLPLRMMVMARMSR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "R4GE71-1", "uniprot_id": "R4GE71_DANRE", "id": "R4GE71-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSHLSEEEQEMIMKVLKRDAELKKAEEDRIKHLQKAIPEEDRRKYMSGEWFYEVKSQRHQDRIHGSDIIMASMKQRKPSVVEYLTKSWGGRSRSISRKD-SEGIMTSPKITRTAESSEHLKERENGDTLEVQQEKLNIGMRSPSKPRHNPFNSVPIELDFEETDLHYTSRPGLRKSLDRGSDSQDNHQKASHSQVNSEVSNAVHNKPPGQKPVPKKRTKINKPQSSVSDTASSVSTQSISSQNIFATADSSIRSPPPRGIPKHSFNEPTLKSQLRQPVVSLSNVHKNSIQEKDSEESKLALGRTEESSHKTENKEKCSTSSPIKLPKSRLPVRASSQLINMPQGLQEKPKIQPRLSLNSITRPDDSRKVEEVIKQRGESNSCLPQSPSMEVERQNISVEMHHPVENAVFAFSDNSKKPLNEITTPQLTHHMSENVENQMAPFPKLETMKTEEKIKKTTTDEHFPRALNITETFNMTNASTDYETESSPLAFNIKQKTSSQEDPKSEVMTDEHITTPTDEQGDSIAKVLEWFSRSSDSSDRLDIDSNVQDMEEDSKFEDLDFDDGVDHTVKPRSNVYLIMPRQSEGPSEVNTIFLEQADWRKEQSVDEPSQNPRKERKTSESTFYKESLIKKPSVDSALTANIVNPEVPVVNISVSRKVQNENKVEALIKKEDKSEVKLADISQQKERSDAEENQRPKIANLKSFWEKENIGPKILIGKSGAPAKNEEIIPSDLAKRSTEEIEDHWRSEPNLKVMSPGLQKIETVWKNVDIEDVGTATQVPIIINESKPLIYANQKTDKIVANSTLDKKCTTSCLKSSSPALDSGSLEGSHDDDSAGGTVSINSSDADHSAQKELETKSKTAQKTSQGPSVKQNSQQENMAERIKQLRSFWEKESRTSVAAKNRSTTTTTRLNQRFTKSEFDLRTIGTEFDDGDEDDVEDITSARGRLSPNFSGHLLRKDKTVVMDGMTTSQFKNLRDFWGGSPVKTGERSPVLDSGNHRSSSPQSPNERANVKDFVNESQNSKTSSSAKMKAFQSPSKKKIMSRQESGPKPDQSQGVSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETITHGLSHSLQPQKGSKTTMVPKSQTGQESRSQQGRRSIKGNLNGKANAMRRATSMFSVNATGEEQNQDLHFQSKKVQSPNLQQVKKAPDTSLTQSRKVQEASYTLPKTSPEISWRDRDKNSQRRTSRTSEDSDSQPLARSYIPRDYQHYLGISEDKSMYTPPPVAEQVDDFICTSFTSSPETNHSCKCPPVKTSTPVHGSPDLQTRSGSLGHHLTTQTDGNIIKGIQNRENESLIQKALKRASSRPVYH-KSMEDISSIARQDQKLKQTDDYMHDNYDA-----------------SSTHLQTSFSTADPEHMKKLSKSVPSFLEKESDGGESDSESSS--RGSVPKWNNRQFTNLSNYSGSTSLSSVSGSVASVYTSDYNSVDVQGSIQFSLNYVHKLREFHIFVVQCQNLAAVDAKRNRSDPYVKSYLIPDPANLGKRKTAVKKKTLNPTYNEILRYRVRMEYLTSQVLNLSAWHNDMFGRNSFLGEIELDLSTWDFNDTERKLLPLKPR-NLFIQTTNSLQPSDLKGQMRLAIRFLPQISHSKNVPGSGEVHIWVKDCKNLPLIRSPTIDPYVKCFVLPDTSKKSRQKTRVLKRTTNPIFNHTMVYDGFRAEDLKEACVELTVWDRDRLASHSLGGLRLGMGTGRSYGVQVDWMDSTTEEVALWRRMMNSPNEWVEDILPLRMITAAKNTWK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*:*:**: *::**:*** **:::*:*:::* : : : * ::*:****.* :**:*:***:*** ***::: : : . ... .*::: *.. . .: .. . : . :. : . :. . *. : ..:.. . . . . : . . : . . . . : * . .... : . . .. * . .::* : : . * . . .: . . .. . ::. . . . :: . . . .. . . : . .::. : .. .. . : . . * **** . . *: . . :*:* :* : **:**:.* . :: : : : . : *:. .. :.*:::* :* ***::::.* : ::* * * : . :*:*. * :*:**.:*** *:*:.::. ::*:*.:**::.**..* *:*:**.**::**..*.*::******* **:** .: **:** * ****:*.******::: : *.:* **:* **.* * *******:*:** **::..: : : .. : .::::*::::*: .:: .***:****:* :**: *. ::.:*** :**:..:*******.: ::.**:********** :** : ********: :* .: :**:*:* ***:*** :*:****. *.***.:*::: * *:* *****: *: : ", "identical_positions": 224, "similar_positions": 287, "identity": "9.73%" }, { "cls_id": "homologset.agr.MGI:1933367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99N48-1", "uniprot_id": "SYTL3_MOUSE", "id": "Q99N48-1", "name": "Synaptotagmin-like protein 3", "aln": "-------------MAHEVDLESFKELERDIILRVLYRDQTVQSTEEERVRKLKSHLQHLRWKGAKSSSQEYKEKCCARCQRALGLLLNRGAVCQGCSHRVCSECRVFLRRTRAWKCTVCFEDRNVKIKTGEWFFEERARKFPTAGRR-ETAGAKLLQSYQRLS-KISVVPPTPPPFSESQCS-SSSRLQELGHFRGFNKSVENLFLSVTTQMRKLSKSQNDMTSEKHLLAMDPRQCVGHTERRSQSDTAVNVTSRKASTPDILKAFHQEDPKHPPDPVLKQDTPPSSPTHSAVFSGGLRHGSLISINSTCTEMGNFDNANVTGEIEFAIHYCVKSCSLEICIKTCKNLAYGEEKKRKCNPYVKTYLLPDRSSQGKRKTRVQKNTLDPTFEETLKYQVDPGQLMTRRLQVSVWHLGTLARRVFLGEVILPLAMWDFKDSTAQNARWYPLRAKAEKYEENIPQNNGELAVRAKLVLPAGPRKPQEAQE--GQLALNGQLCLVVLGAKNLPVRSDGTLNSFVKGCLTLPNQQKLRVKSPVLKKQACPQWKHSFVFNGVSSSQLRQSTLELTVWDQAIFGMNDRLLGEARLGSKGGAAGCPDSGSQSKLQWHRVLSSPNLWTDMTLVLH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PU77-1", "uniprot_id": "E9PU77_RAT", "id": "E9PU77-1", "name": "Synaptotagmin-like protein 3", "aln": "-------------MAHEVDLESFKELERDIILRVLYRDQTVQSIEEERVRNLKTHLQHLRWKGAKSSSQEYKEKCCARCQQTLGLLLNRGAVCQGCSHRVCSECRVFLRKTHAWKCTVCFEDRNVKIKTGEWFFEERARKFPTAGRR-ETAGARLLQSYQRQSSKISVVPPTPPPLSESQCGGSPNRLQELGHFRGFNKSVENLFLSVTTQMRKLSKSQNDMTSEKHLLAMDPRQCMGHTERRSQSDTAVNVTSRKTSTPDILKAFHQEDPRHPPSPVLKQDTPPSSPTHSTVFSGGLRHGSLISVNSTCTEMGNFDNANVTGEIEFAIHYCVNSHSLEICIKTCKNLAYGEDKRRKCNPYVKTYLLPDRSSQGKRKTRVQKNTLDPTFEETLKYQVDPAQLATRRLQVSVWHLGTLARRVFLGEVILPLATWDFEGSAAQNARWYPLRAKAEKYEENIPQTNGELAVRAKLVLPVGPRMLQEAQE--DQLALNGQLCLVVLGAKNLPVRSDGTLNSFVKGCLTLPDQQKLRVKSPVLKKQACPQWKHSFVFNGVSSSQLRQSTLELTVWDQAMFGMNDRLLGEAKLGSKGGAPGCTDSCSQSKLQWQKVLSSPNLWTDMTLILH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VX76-1", "uniprot_id": "SYTL3_HUMAN", "id": "Q4VX76-1", "name": "Synaptotagmin-like protein 3", "aln": "-------------MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEERAKKFPTGGKH-ETVGGQLLQSYQKLS-KISVVPPTPPPVSESQCSRSPGRLQEFGQFRGFNKSVENLFLSLATHVKKLSKSQNDMTSEKHLLATGPRQCVGQTERRSQSDTAVNVTTRKVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVLH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFP0-1", "uniprot_id": "F1QFP0_DANRE", "id": "F1QFP0-1", "name": "", "aln": "MKLEQKNWEDRKNDFCPLDLGLFQALERERVLEVLQRDKALRTIDADRVRRLRVELHGLCLQTSRIISRPFGQRSCARCQRVLGKFWDCGSVCCGCSHRICNRCQVVR-SAHDWKCTVCHAYREFKIKSGEWFLEQQAKKFPSVKENSETTGDKMLQSYQRLS-FIAVVPPTPPPFYN-----PPSFNRLEEHKKPFTKSMENLVASVSAHIKKLSKSQNDLSEVAGQLTVDHG-HMMYSRRKSLSDGAINRALCKVPSLPILSTAQSTS---TSTLCLTDDDVSSTSAYSDDQRD---SNSSTGMDSVLFEN----TISVTGEIEVVLAYNNRTSCLEITIKACRNLMFR-DTKKKCHPYVNVCLLPKKCHNFKMKTAVRK-GKNPVYNETFTCVLSADLLSSAVLQLSVWHSRGLKRRLFLGETLIRLADMDLEDTDSQRSLCCKLNPKAPQLGGDAELQFTSVLLLIQAQFHTLPHNNTQTHG--VLLGAPGQLTVLFTDVSKLLSVS---KTAHFEGILCLPGHRELVRKTSALKKTDG---SIRMSFSSLSQQELQQATLTLNLWEKNCLLTSARLHKES--------------------SWQHLQRMPGVWQEFNLQLQVVQT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** :: ***: :*.** **::::. : :*.*.*: .*: * : :: . . ::.*****:.** : . *:** *****:* .*:*. :: ******. *:.***:**** *::*:***: .. **.* ::*****: * *:********. : ... : : : *.**:***. *::::::********::. *: . : :.*:* ** *:* : *..: **.. :. . .. *.:: .*:.: * . .* .::*. * . .******..: * .: .*** **:*:** : :.::**:***:. ***.:. : * ** *:: :*.::**:. : . * : **:**** * **:****.:: ** *::.: :* *..** : . .: : : : *: ::: . *** ::. ...:* . .:..:* * **.:::* *:..*:* . : *..:: :*:*::* *.:*:: : . ** : .*::: *.:* ::.* *: ", "identical_positions": 178, "similar_positions": 208, "identity": "28.3%" }, { "cls_id": "homologset.agr.MGI:1933378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q642A5-1", "uniprot_id": "DPOE3_RAT", "id": "Q642A5-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MAER----PEDLNLPNAVITRIIKEALPDGVN---ISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKG-KKEASEQKKKDKDKK-------------------DCEEQDKSREEE-DEDEERLDEEEQNEEEEVDN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRF9-1", "uniprot_id": "DPOE3_HUMAN", "id": "Q9NRF9-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MAER----PEDLNLPNAVITRIIKEALPDGVN---ISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKG-KKEASEQKKKDKDKKT------------------DSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKP7-1", "uniprot_id": "DPOE3_MOUSE", "id": "Q9JKP7-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MAER----PEDLNLPNAVITRIIKEALPDGVN---ISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFITPLKEALEAYRRDEKG-KKEASEQKKKDKDKK-------------------DSEEQDKSREVE-EEDEERLDEDDQNEEEEIDN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V444-1", "uniprot_id": "DPOE3_DROME", "id": "Q9V444-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MVER----IEDLNLPNAVIGRLIKEALPESAS---VSKEARAAIARAASVFAIFVTSSSTALAHKQNHKTITAKDILQTLTELDFESFVPSLTQDLEVYRKVVKE-KKESKASKK---DSN-------------------TAENANASATATAEEAPE-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04603-1", "uniprot_id": "DPB4_YEAST", "id": "Q04603-1", "name": "DNA polymerase epsilon subunit D", "aln": "MPPKGWRKDAQGNYPTTSYIKEQENITIQDLLFPKSTIVNLAREVPQQSGKKLLINKDASLALQRGATVFVNHLLLFAREIAKSQDKKSCSVDDVLSALDHIGHSALKGPVRDKLDEYQAAVEQRKKEKLDSGEVDADGDIDMGEDKENVPVEKVKEHDEIEEQGDALQDVEESSEKKQKTESQDVETRVQNLEQT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :** :*::.* .: :*. :. . :.*:* *: *.*:**. . : :* . .:*: ...*:*.:: .: .. : .: : *: *: : *** . : * . *: . : :. : ", "identical_positions": 24, "similar_positions": 55, "identity": "12.24%" }, { "cls_id": "homologset.agr.MGI:1933382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26376-1", "uniprot_id": "IFM3_RAT", "id": "P26376-1", "name": "Interferon-induced transmembrane protein 3", "aln": "MNHTSQAFVNAATGGQPPNYERIKEEYEVSELGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDMTGAQAYASTAKCLNISSLVLSILMVIITIVT-----VVIIALNAPRLQT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J93-1", "uniprot_id": "IFM2_MOUSE", "id": "Q99J93-1", "name": "Interferon-induced transmembrane protein 2", "aln": "MSHNSQAFLSTNAG-LPPSYETIKEEYGVTELGEPSNSAVVRTTVINMPREVSVPDHVVWSLFNTLFFNACCLGFVAYAYSVKSRDRKMVGDVVGAQAYASTAKCLNISSLIFSILMVIICIIIFSTTSVVVFQSFAQRTPHSGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01628-1", "uniprot_id": "IFM3_HUMAN", "id": "Q01628-1", "name": "Interferon-induced transmembrane protein 3", "aln": "MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIP----VLIFQAYG--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01629-1", "uniprot_id": "IFM2_HUMAN", "id": "Q01629-1", "name": "Interferon-induced transmembrane protein 2", "aln": "MNHIVQT-FSPVNSGQPPNYEMLKEEQEVAMLGVPHNPAPPMSTVIHIRSETSVPDHVVWSLFNTLFMNTCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGIFMTILLIIIP----VLVVQAQR--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* *: ... . **.** :*** *: ** * ..* :***:: *.***************:* *****:*:**************:.************** :*::.*:*.*: *: *::. ", "identical_positions": 75, "similar_positions": 31, "identity": "51.72%" }, { "cls_id": "homologset.agr.MGI:1933383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EP66-1", "uniprot_id": "HCAR2_MOUSE", "id": "Q9EP66-1", "name": "Hydroxycarboxylic acid receptor 2", "aln": "MSK---SDHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLTDNYVHNWDWRFGGIPCRVMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHFLNKISNRTAAIISCFLWGLTIGLTVHLLYTNMMTKNGEAYLCSSFSICYNFRWHDAMFLLEFFLPLAIILFCSGRIIWSLRQRQMDRHAKIKRAINFIMVVAIVFIICFLPSVAVRIRIFWLLYKYNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPNFFSTCINRCLRKKTLGEPDNNRSTSVELTGDPSTTRSIPGALMADPSEPGSPPYLASTSR------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80Z39-1", "uniprot_id": "HCAR2_RAT", "id": "Q80Z39-1", "name": "Hydroxycarboxylic acid receptor 2", "aln": "MSK---QNHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLTDNYVQNWDWRFGSIPCRVMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHFLNKISNRTAAIISCFLWGITIGLTVHLLYTDMMTRNGDANLCSSFSICYTFRWHDAMFLLEFFLPLGIILFCSGRIIWSLRQRQMDRHVKIKRAINFIMVVAIVFVICFLPSVAVRIRIFWLLYKHNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPNFFSTCINRCLRRKTLGEPDNNRSTSVELTGDPSTIRSIPGALMTDPSEPGSPPYLASTSR------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDS4-1", "uniprot_id": "HCAR2_HUMAN", "id": "Q8TDS4-1", "name": "Hydroxycarboxylic acid receptor 2", "aln": "MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49019-1", "uniprot_id": "HCAR3_HUMAN", "id": "P49019-1", "name": "Hydroxycarboxylic acid receptor 3", "aln": "MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGPTSNNHSKKGHCHQEPASLEKQLGCCIE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: .:*** *: ********: *.***********:*******************************************: * **:. **:**.****::***:*************************** ****** *******:***:*:******* ..: :** * :* *****:.*:**:***********.******.**************.******.*********:*******.***:*****:. ..:**::* ******* ***************************** *****::* *****************.. *. * **:::..** **.**..** ", "identical_positions": 280, "similar_positions": 55, "identity": "72.35%" }, { "cls_id": "homologset.agr.MGI:1933384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CAB8-1", "uniprot_id": "CAST2_MOUSE", "id": "Q8CAB8-1", "name": "Cytosolic arginine sensor for mTORC1 subunit 2", "aln": "-----------MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLSFTNGFVKPKMVQRPVIHPLSSPSNRFCVTSLDPDTLPAVATLLMDVMFYSNGVKDPMAASDDCGHIRFFSFSLIEGYISLVMDVQTQQRFPSHLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENISGVIHALKVSQAGKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V665-1", "uniprot_id": "G3V665_RAT", "id": "G3V665-1", "name": "", "aln": "-----------MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLSITNGFVKPKMVQRPVIHPLSSPSNRFCVTSLDPDTLPAVATLLMDVMFYSNGVKDPMASSDDCGHIRFFSFSLIEGYISLVMDVQTQQRFPSHLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENISGVIHALKVSQAGKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NHX0-1", "uniprot_id": "CAST2_HUMAN", "id": "A6NHX0-1", "name": "Cytosolic arginine sensor for mTORC1 subunit 2", "aln": "-----------MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLGITNGFVKPKLVQRPVIHPLSSPSNRFCVTSLDPDTLPAVATLLMDVMFYSNGVKDPMATGDDCGHIRFFSFSLIEGYISLVMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENINGVISALKVSQAEKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NAP1-1", "uniprot_id": "CAST3_HUMAN", "id": "Q8NAP1-1", "name": "Putative protein CASTOR3P", "aln": "MSCRGRGAGGRWNSTSWSTGCKLPASPRRVSRCSPTGLIKLAFLFSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGMTKIAKSVIAPLADQNISVFMLSTYQTDFILVLKRDLPFVTHTLSSEFTILWSVARL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::.: .:. . ******** *************************************************************:******************************* :***************** * ", "identical_positions": 118, "similar_positions": 12, "identity": "34.71%" }, { "cls_id": "homologset.agr.MGI:1933388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0Y0-1", "uniprot_id": "A0A0G2K0Y0_RAT", "id": "A0A0G2K0Y0-1", "name": "", "aln": "--------------------------MAAQGEPGYLAAAQSDPGSNSE--------RSTDSPVAGSEDDLVAAAPLLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEAVKEAKEMIMAVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEDTGCHIHFPDSNRNNQVEKSNQVSIAGQPAGVESARARIRELLPLVLMFELPIAGILQPVPDPNTPSIQHISQTYSVSVSFKQRSRMYGATVIVRGSQNNTNAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNVKHIMQRTGAQIHFPDPS----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEDIDVDPQVITQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVSIATSLS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPN---------SLLNALN--SSVSPLQSSSSGTPSPTTLWASSIPNTASATGFSTIPHLMIPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKNISASINGHVQPPNMKYGPLSTSSLGEKVLSSNHGDPSMQTAGPEQASPKSNSVEGCNDAFVEVGMPRSPSHSGNAGDLKQMLGPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDTELSATESPLADKKAPGSERAAERAAAAQQ------------NSERARLASQPPYVH-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTAYEGSSLSLSRSSSREHLASGSESDNWRDRN------GIGPMGHSEFSAPIGSPKRKQNKSREHYLSSSNYMDCISSLTGSNGCNLNSCFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELSKNRRKLFEPPNTPTTCTSFLEGGVSGRLPRQYHSDIAS-VSGRW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MQ1-1", "uniprot_id": "BICC1_MOUSE", "id": "Q99MQ1-1", "name": "Protein bicaudal C homolog 1", "aln": "--------------------------MASQSEPGYLAAAQSDPGSNSE--------RSTDSPVAGSEDDLVAAAPLLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEDTGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARARIRELLPLVLMFELPIAGILQPVPDPNTPSIQHISQTYSVSVSFKQRSRMYGATVTVRGSQNNTNAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNVKHIMQRTGAQIHFPDPS----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEDIEVDPQVIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVSIATSLS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSATPN---------SLLNALN--TSVSPLQSSSSGTPSP-TLWAPPIANTASATGFSTIPHLMLPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKNISASINGHVQPANMKYGPLSTSSLGEKVLSSNHGDPSMQTAGPEQASPKSNSVEGCNDAFVEVGMPRSPSHSGNAGDLKQMLGASKVSCAKRQTVELLQGTKNSHLHGTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQ------------KSERARLASQPTYVH-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTAYEGSSLSLSRSSSREHLASGSESDNWRDRN------GIGPMGHSEFSAPIGSPKRKQNKSREHYLSSSNYMDCISSLTGSNGCNLNSCFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELSKNRRKLFEPPN--ASCTSFLEGGASGRLPRQYHSDIAS-VSGRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H694-1", "uniprot_id": "BICC1_HUMAN", "id": "Q9H694-1", "name": "Protein bicaudal C homolog 1", "aln": "--------------------------MAAQGEPGYLAAQ-SDPGSNSE--------RSTDSPVPGSEDDLVAGA-TLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPS----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVTIATSPS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPN---------SLLNALN--SSVSPLQSPSSGTPSP-TLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQ------------NSERAHLAPRSSYVN-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRDRN------GIGPGSHSEFAASIGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPN---ARTSFLEGGASGRLPRQYHSDIAS-VSGRW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HRB2-1", "uniprot_id": "A0AC58HRB2_DANRE", "id": "A0AC58HRB2-1", "name": "", "aln": "-----------------------------MAEP--LSFMHHDHGSSSE--------RSDDSPSAVSEDDSSGHCGHISPPDP-DWTEERFRVDRKKLETMLLAANEGR-INGDD-FFQKVMDETNTQIAWPSKLKIGAKSKKDPHIKVSGKRDDVREAKEKIMSVLDTKSHRVTLKMDVSHTEHSHVIGKGGHNIKRVMEETGCHIHFPDSNRHSQAEKSNQVSIAGQLTGVEAARVKIRELLPLVLMFEC--SGVVQLV-DCSSPVVQHISHTYNVSISFRPPSRLYGNTAIVRANQNNSSGVKRGTALLLEHLAGSLASSVLVSTQLDIAPQHHHFLLGRNGANIKLISQRTGAHIHFPEISPH-NSNASRSAVYIQGSIDAVCAARQQIMGCLPLVLLFDIKEETEVASQVITTLMEQLDVFISIKPKPKQPSKSVIVKSVERNAGSLYEVRRILLGLESSCLSSSVSSVSVNGHISSSPPRIASIGLDTLASAGLRLSTLAGLLRSSVSPVPNGSPNPSCALNGHGSVLNIQNGVNNTQHIHTPAHTHSHTPSLWASALSSAADAAGFS--TDLMLQSVSQATLGGLLLSGVQSQAHAHTPSPPPGLAPIHKTVS---------AEHLNGHLASS--VYSRISSVSL-----NSAHCDMAQEGIGHTQSEAKS--TDEGSDTFVEVGMPRSPSHSANGSELKQMLASCTVSPGKRQTVELLQRTKNTLLH-VECVLAD----SDDNPMTDKRAPGSERAAERRLAPHMQVYMLMCKHCTHNSAQTKSHSQCLCVNIFQAFDYEKKKLLATKAMLKKPVVTEIRTPTNTWSGLGFSKSMPAESIKELRRAHHVPYKPSMGTTYEDSHLSMSHSGIQEGLINDTKSDNWGDLNGNVNINGNGPSGNSEFSQTVSSTKRIKNKSREQYLSSSNYMDSIS-LTGSNGISLSSSLKGTDLPELFSKLGLGKYTDIFQQQEIDLQTFITLTDPDLKELGITTFGARRKMLLAISELNKSRRKLFDTAN---IRSSFLEGGASGRLTRHFHSDMAS-VSGRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24009-1", "uniprot_id": "BICC_DROME", "id": "Q24009-1", "name": "Protein bicaudal C", "aln": "MLSCASFNKLMYPSAADVAKPPMVGLEVEAGSIGSLSSLHALPSTTSVGSGAPSETQSEISSVDSDWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNRSNPTEKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQQLLGNLPVALIFDFPDNHNDASEIMS-LNTKYGVYITLRQKQRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDY-----------YFMPKDKDLNLAYRTQLTALLAGYVDSPKTPSLLPPS----------LAGQLTPYANNNHLLLNANGLATPTGVCAPTQKYMQLHNSFQQAQNRSMVAGGQSNNGNYLQVPGAVAPPLKPPTVSP--------------------------------------------------RNSCSQNTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAGSQNRAHYSPDSTYGSEGGGVGGGGGGGARLG---RRLSDGVLLGLSNSNGGGGNSGGAHLLPGSAESYR---------------SLHYDLGGNKHSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPAPAPLENG---------------------------ENGAAGGGASSGWRLPP--------GLGSPYGLSATTGLLDATPVNRR------------------------MQLAKHKDIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAIHTLLANEAACSTMPS-----SSSSQNSSSPRFSGSAAPGAERRPSNQW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *: .:.* :* *. . .* . . : : ***:***:*** :: * . . .* : **:.:*: *:* ::**.:************::: ** : *:.*** *:: **::. ** :*****:*:**::**:**:***::*::* ********* . .*******:.*. *** **. :* **:: ** * : * .:* :: *. .:.:.: * .::: . *:..:::: *: .* :*::. . *:** : *..*::*:.*** :: *:*. *: * :** ::* **: * . .:* * :.* *: * *** ::* **:.*:**: :: : .:.:: * : .*:*::: * :*.: :::**.**: .:**.*: :* * :. :. . : . * : *: * : . . .*. : . . . . : : . . : *.. .*. . : : .*:. . * .*: .* : . : : * . ...: : .:.:: . *.: *..... :: . : ... .: * *:* . ... . .*. : . : :***:: *: *. *** :.**. *:****.:* *:*:*.: ** : * .: .. *..* * . :: . . . : . * .*: *::.*** :* .:* :****:.* ***: :* ****::****:*:* ** * .. .. :* :.. * *:. .. *.:*", "identical_positions": 223, "similar_positions": 291, "identity": "21.06%" }, { "cls_id": "homologset.agr.MGI:1933395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFJ6-1", "uniprot_id": "D3ZFJ6_RAT", "id": "D3ZFJ6-1", "name": "Serine beta-lactamase-like protein LACTB, mitochondrial", "aln": "MYRFLSSVTSRATATAGPALGGGRRGAHGRPGLPMLSLGWAGGLGLGLGLALGAKLAIGLRGAVPIQSPADP--EASGATELPHEQAPGPGSPHTPASPAARGFSRAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDLPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDMKKVKEEKAYKALKMMKGTPPP-DQEKELKEKGGKDNDKSDSPKAKAEQDSEAKCRSAKPGKKKNDFEQGELYLKEKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERTSGYKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGLFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVEKKQTHGACRKQRHYASHTGGAVGASSVLLVLPEELDPEAVNNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP89-1", "uniprot_id": "LACTB_MOUSE", "id": "Q9EP89-1", "name": "Serine beta-lactamase-like protein LACTB, mitochondrial", "aln": "MYRLLSSVTARAAATAGPAWDGGRRGAHRRPGLPVLGLGWAGGLGLGLGLALGAKLVVGLRGAVPIQSPADP--EASGTTELSHEQALSPGSPHTPAPPAARGFSRAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDLPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDIKKVKEEKAYKALKMVKGTPPPSDQEKELKEKGGKNNEKSDAPKAKVEQDSEARCRSAKPGKKKNDFEQGELYLKEKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGYKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGQFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVEKKQTYGSCRKQRHYASHTGGAVGASSVLLVLPEELDSEAVNNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83111-1", "uniprot_id": "LACTB_HUMAN", "id": "P83111-1", "name": "Serine beta-lactamase-like protein LACTB, mitochondrial", "aln": "MYRLMSAVTARAAAPGGLASSCGRRGVHQRAGLPPLGHGWVGGLGLGLGLALGVKLAGGLRGAAPAQSPAAPDPEASPLAEPPQEQSLAPWSPQTPAPPCSRCFARAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDIPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDIKKVKEEKAYKALKMMK------ENVAFEQEKEGKSNEKNDFTKFKTEQENEAKCRNSKPGKKKNDFEQGELYLREKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGCKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGLFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVERKQTYGSCRKQRHYASHTGGAVGASSVLLVLPEELDTETINNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*:**:**:*..* * . ****.* *.*** *. **.************.**. *****.* **** * *** :* .:**: .* **:***.*.:* *:*********************************************************************************:***************************************:**************:* :: :** **.*:*.* .* *.**:.**:**.:****************:******************************************:** ******************************************************************************** **********************************************:***:*:*****************************.*::*************************************:*", "identical_positions": 471, "similar_positions": 50, "identity": "85.17%" }, { "cls_id": "homologset.agr.MGI:1933403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ22-1", "uniprot_id": "ERAP1_RAT", "id": "Q9JJ22-1", "name": "Endoplasmic reticulum aminopeptidase 1", "aln": "------------MPSLLSLV-LTFLAVSSPSCCQNSDTASPKASNGASFPWNNMRLPEYITPIHYDLMIHANLST--LTFWGKTEVEITVSQPTSTIIMHSH---QLQISKATLRRGAEEMLPEEPLKLMEYSAHEQVALLTAQP-LLAGSVYTVIITYAANLSENFHGFYKSTYRT-QEG-ERRILAATQFEPTAARMAFPCFDEPALKASFSIKIKRDPRHLAISNMPLVKSVTVAEG-LIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSGVKVSVYA---VPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQ--------------------DLAAIPDFQSGAMENWGLTTYRESALLYDK-EKSSASSKLGITMTVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVT-------VTHPELKVEEYFFGKCFN-AMEVDALNSSHPVSTPVENPAQIREMFDEVSYEKGACILNMLRDYLSADTFKRGIVQYLQKYSYKNTKNEDLWNSMMHICPTDGTQT----MDGFCSRNQHSSSTSHWR-QEVIDIKSMMNTWTLQKGFPLITITVRGRN----VHLKQEHYMKGSECFPE---TGSLWHVPLTFITSKSDSVQRFLLKTKTDVIILPEAVEWIKFNVGMNGYYIVHYGDDGWASLNGLLKEAHTTISSNDRASLINNAFQLVSIGKLS----IEKALDLILYLKNETEIMPIFQGLNELIPMYKLMEKRDMVEVETQFKDFLLR-LLKDLINKQTWTD---EGSVSERMLRSQLLLLACVHRYQLCVQRAERYFREWKAS-----NGNMSLPIDVTLAVFAVGAQNTEGWDFLYSKYQSSLSSTEKSQ-IEFSLCISQDPEKLQWLLD-----QSFKGEIIKTQE--FPHILTLIGRNPVGYPLAWKFLKENWNKIVQKFELGSSSIAHMVMGTTNQFSTRARLEEVKG-------------FFSSLK-KNGSQLRCVQQTIETIEENIR-WMDKNFDKIRLWLQKERQELL-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQH2-1", "uniprot_id": "ERAP1_MOUSE", "id": "Q9EQH2-1", "name": "Endoplasmic reticulum aminopeptidase 1", "aln": "------------MPSLLPLV-LTFLSVSSPSWCQNSDIESLKASNGDSFPWNNMRLPEYMTPIHYDLMIHANLST--LTFWGKTEVEIIASRPTSTIIMHSH---HLQISKATLRRGAGEMLSEEPLKVLEYPAHEQVALLAAQP-LLAGSLYTVIIDYAANLSESFHGFYKSTYRT-QEG-EMRILAATQFEPTAARMAFPCFDEPALKASFSIKIKRDPRHLAISNMPLVKSVNVAEG-LIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSGVKVSVYA---VPDKINQADYALDAAVTLLEFYEDYFNIPYPLPKQ--------------------DLAAIPDFQSGAMENWGLTTYRESSLLYDK-EKSSASSKLGITMIVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVT-------VTHPELKVEDYFFGKCFN-AMEVDALNSSHPVSTPVENPAQIREMFDDVSYEKGACILNMLRDYLSADTFKRGIVQYLQKYSYKNTKNEDLWNSMMHICPTDGTQT----MDGFCSRSQHSSSTSHWR-QEVVDVKTMMNTWTLQKGFPLITITVSGRN----VHMKQEHYMKGSERFPE---TGYLWHVPLTFITSKSDSVQRFLLKTKTDVLILPEAVQWIKFNVGMNGYYIVHYADDGWASLSGLLKEAHTTISSNDRASLINNAFQLVSIEKLS----IEKALDLTLYLKNETEIMPIFQALNELIPMYKLMEKRDMIEVETQFKDFLLK-LLKDLIDKQTWTD---EGSVSERMLRSQLLLLACVRNYQPCVQRAERYFREWKSS-----NGNMSIPIDVTLAVFAVGAQNTEGWDFLYSKYQSSLSSTEKSQ-IEFSLCTSKDPEKLQWLLD-----QSFKGEIIKTQE--FPHILTLIGRNPVGYPLAWKFLRENWNKLVQKFELGSSSIAHMVMGTTDQFSTRARLEEVKG-------------FFSSLK-ENGSQLRCVQQTIETIEENIR-WMDKNFDKIRLWLQKEKPELL-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ08-1", "uniprot_id": "ERAP1_HUMAN", "id": "Q9NZ08-1", "name": "Endoplasmic reticulum aminopeptidase 1", "aln": "MVFLPLKWSLATMSFLLSSL-LALLTVSTPSWCQST-EASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTT--LTFWGTTKVEITASQPTSTIILHSH---HLQISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEP-LLVGLPYTVVIHYAGNLSETFHGFYKSTYRT-KEG-ELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEG-LIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYA---VPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQ--------------------DLAAIPDFQSGAMENWGLTTYRESALLFDA-EKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVS-------VTHPELKVGDYFFGKCFD-AMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKG----MDGFCSRSQHSSSSSHWH-QEGVDVKTMMNTWTLQKGFPLITITVRGRN----VHMKQEHYMKGSDGAPD---TGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLS----IEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIR-LLRDLIDKQTWTD---EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKES-----NGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQ-IEFALCRTQNKEKLQWLLD-----ESFKGDKIKTQE--FPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKG-------------FFSSLK-ENGSQLRCVQQTIETIEENIG-WMDKNFDKIRVWLQSEKLERM-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWF2-1", "uniprot_id": "A0A8M3AWF2_DANRE", "id": "A0A8M3AWF2-1", "name": "Aminopeptidase", "aln": "------------MLFLAKYFHFTLVALFCALFAGNHAMTVNKNKTVLPFPWDKMRLPEIVKPQHYDLLIHPNLTS--LTFTGEVQIQIEVKQDTRAIILHSK---NLQVSKALL-LGSRQHHHHQDLQISEFEANEQIALFSEGFTFEKG-SHVVHLEFYANLSDSFHGFYKGQYTT-NSG-EVRMLASTQFEPTHARAAFPCFDEPAFKANFTIRVRRESRHISISNMPKLRTVELADG-ILEDQFDTMVKMSTYLVAFIICDFHSISKKSQHGVEISVYT---VPEKISQAEYALDTAVTMLDFYDEYFDIPYPLPKH--------------------DLAAIPDFQSGAMENWGLSTYRESGLLFDP-EKSSSSDKLGITKVIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEYVSVN-------ITHPELQVNDYFLEKCFT-ALSVDSLSSSHPVSTPVENPAEISEMFDDVSYRKGACILNMLRDFLTPEVFKYGIINYLKKHSYQNTVNSHLWESLTNICTSDGLDSGRLKLDGFCSKHTAETPASKWFKEDSVDVGAIMDTWTLQEGFPLITVEVKGQE----VTLKQERFLKGAESSNS---SSFLWQVPLTYITSGSNAVQRFLLKTERDVFYLPEKVEWIKFNVDLRGYYIVHYESGGWDCLIKQLRMNHTVFSSNDRASLIHDIFQLVSIEKVP----LDKALNLSLYLSKESEIMPVTQGFSELVPLYKLMEKRDMQELENQLKSHLVK-LFQPLIDRQSWSD---NGSVSERMLRNYLLLFACVRRYPSCVSTATQLFHKWKES-----DGKMWLPTDVSLVVYTEGARTDDGWDFLLEKYKRSVSPSEKWM-IKAALSYSPLAHKLQWLLE-----RSSEGEIMKTQD--LPSMLISVSKNPKGFKLAWDFLKSNWGKLVKKFDLGSSAISRVVVGVTDQYSTKEMLDEVEL-------------FFGSLAQDQGSGLRSIQQALEKIQQNIL-WMDRNVPLLKAWLDHHTS----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PE71-1", "uniprot_id": "A0A8M1PE71_DANRE", "id": "A0A8M1PE71-1", "name": "Aminopeptidase", "aln": "---------MATMTRLPVLLNLIVLPIHLWAAVTPEPTSFPISSSGEPFPWNKMRLPDTISPLHYNLLIHPNLTS--LDFTGSVQIQIEVLQDTKTIILHSK---NLQISSARL-LDAN-IAQQQPLKVLEYPYFQQIALVSDKALLKRGHVYSVELHFAANLSESFHGFYKSTYRT-SKG-DVRVVASTQFEATSARAAFPCFDEPAFKANFSVQIRREAKHIALSNMPKLRTLELKNG-LFEDQFDVSVKMSTYLVAYIVSDFLSISKTSQHGVQISVYA---VPEKIDQAEFALDAAVKLLDFYDDYFDIPYPLPKQEKPTIKHAKEEFSVYIICFVDLAAIPDFQSGAMENWGLTTYRESALLFDP-HKSSASDKLGITMIIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEFVSVN-------ITNPELQVEDYFLGKCFE-AMEVDSLSSSHPVSTPVENPAQIQEMFDDVSYDKGACILNMLREFLTPKIFKLGIVKYLKHYSYQNTVNSNLWESLTNVCDSDGLDEGRLKGDESCRHSASNTGASKWHSEDELDVKAMMETWTLQEGFPLITIAVKGRE----VRLSQERYLKSDDLSQT---SSFLWQVPLTYITSDSTTVHRFLLKTKTDVLYLPEEVDWIKFNVDMSGYYIVHYEGSGWDDLITLLKHNHTALSSNDRASLINNAFQLVSVGKLP----LDKALDLTLYLSKETEIMPVTQGFNELVPLYKLMEKRDMVELENQMKGYILQ-LFQKLIEQQLWTD---EGSVSERMLRSYLLLFGCVRGHPPCVSNATQLFNLWRDS-----DGNMSLPNDVTMAVFSVGARTEDGWDFLFEKYKESMYVSMKSR-IKQALMTSPLDHKLKWMME-----QSLEGELIKTQD--LPYVVTSVSRNPKAYKHAWDFLQANWDSLIKKFDLGSHSIAHMVVGVTNQYSTREMLAEVRN-------------FFSLLQPETGAELRCIQQAVENIEENIR-WMDKNLPLLKAWLHRYYDQQKNTEL---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VD87-1", "uniprot_id": "Q9VD87_DROME", "id": "Q9VD87-1", "name": "Aminopeptidase", "aln": "-------------------------MITPPSGVVVLVTLGLLVSGSMGERERSLRLPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHAKNLTDIQITVHRLMAEGSEIVDDLTHTLHPTAALLIIHPIENYQAFEEGQQYRLEILYTAIMASRPAGLYYMDYRD-EENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSSHSAISNMP-VKEVLAHGD-LKTTSFHTTPPISTYLVAFVISDFGSISETYR-GITQSIYT---SPTSKEKGQVALKNAVRTVAALEDYFGVSYPLPKL--------------------DHVALKKNYGAAMENWGLITYKDVNLLKNI-SSDGQKRKLDLITQN-HEIAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITD-------LIYPNDKMMDMFMTHEADSAYSYNSFFDVHPMSHYVEGEKDIMGVFDIISYKRGACVIKMFHHAFRQKLFVRGISHFLEKYRYSVANELNLFDALHSELQDDEYFS------------HQPWASRIREIMLSWTHSEWLPILVVTRNYENNTITFTQRS----VHMKDELWWIPINFATT---QSPNFEDTQVDMFMPP---QPQYTVSLEDLNIHVSGRDWIMVNKQHTGFYLVRYDTDNLMAIARQLQTNHSVIHPINRLGLFRDLGPLIEHNEIEQ---VEVVFELLKYLELEEDVLTWNQLQDTIECLTRNLHG---TSSQSLFNEFVRR-LVGPTFRRVYVEQ---GVNLAEDGMFRGILEIACSADLPECLEYTRRLAKEHIIDKIYFKDGSDYHAIIDSVLCMGVRYLSDQDFQRIIDMMQEIDRASVYYDDIIYALRCTQSHRHLLYYLEGLMGENSTHMVLSEFED--LMYLLYIYKSNLASRPVIWQYIERNYKVLCRAPNFLEHFKQLAGFVPRHQRSHFERLRQTIANHMMQEGLNTNQTLIEVDSPLVGKKMKITENFQDKFEQQIHKWLLNELPQATSRSDALLSASLSAANGSSRPQGVLKEATRVLRSALRIVDMYR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40462-1", "uniprot_id": "TM108_YEAST", "id": "P40462-1", "name": "Protein TMA108", "aln": "-------------------------------------MSDNLLSLENPVVPSHYELRLEIDPKQSSPNFKGSAIIH-LKFNPNSTTLASIEDSFTQFKLHSKDLIVLSAHATIGSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGKIRDIKTHHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQYKAVSNTPVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGDRTIPVSIYAPWDIANAAFTLDTVQKYLPLLESYFKCPYPLPKL--------------------DFVLLPYLSDMAMENFGMITIQLNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIG----------------------------KFLKSQNITNFVSSWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDVPYQVPLFGVLPDGKMDTKNVLLTDRTLKFDYP---ILVINHLAQGYYRVSYESEECYALIN-DKITEETLSEIDLRKIFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDRASLTSSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLFLNKNSAKCAELCQIYFKHLLQGP---RSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQNSSETAMLIQNGAIESLGFCLDSDIVKKTLNFITSNIESEGMELALFGFNYNFKKRLNKNEKPQDQVVRETIWEWYMGNFDQWARKATRKGTTTG-------------DHLHKALRSISLIIFQMFVADEPQKIEKFINLEKEKLGQSLLSLDDIWASVQQDEESRKTIRRDLASLV-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* * . : . * * : :*:: :. . . : . : : . *:: : . . :.:*: :. . *** ***. *:.* :.: . : ::** * . * ::* :..: : *: :. : :: . * . :. :*. . : :.** .***** * . : . ****:*: * : ** . . : **:.***:** :: : * *:**.**.:: .: : : . * . :. : . . : :** :* :* ::. :: . : *: ::. : . . : : . . .: . :. . :.:. : . . :. . : : : : .* *:* * * : : . .. : :: : :: . :. :.: :: :. : .. :: .: : :. : : . . : : * . . . .. : . . :. : . : * : * . . : : : : :.: . :. . .* : . . : : ::* :: : ", "identical_positions": 68, "similar_positions": 215, "identity": "6.4%" }, { "cls_id": "homologset.agr.MGI:1933407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LSP0-1", "uniprot_id": "F1LSP0_RAT", "id": "F1LSP0-1", "name": "Transmembrane protease serine 5", "aln": "--------------------------MSSTLDDQCPMEIR-------------------------------CTEEGPGPGIFRAELG-----------------------------DQQ-----------QPISQSQRWCCLQRGCVILGALGLLAGAGVGSWLLVLYLWPAASPPVSVTLQEEEVTLSCPGVSSEEKLLPSLPKAVSFRINGEDLLLEVQVRARPDWLLVCHEGWNPALGMHICQSLGYFRLTQHKAVNLSDIKLNRSQEFAQLSARPGSLVEEAWQPSTNCPSGRIVSLKCSECGARPLASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPYWVVTAAHCMYSFRLSRLSSWRVHAGLVSH--SAVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVSAVCLPAKEQHFPQGSQCWVSGWGHTDPS-----HTHSSDTLQDTMVPLLSTDLCNSSCMYSGALTHRMLCAGYLDGRADACQGDSGGPLVCPSGD--TWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWIHDTVQVR-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER04-1", "uniprot_id": "TMPS5_MOUSE", "id": "Q9ER04-1", "name": "Transmembrane protease serine 5", "aln": "--------------------------MSPTLDDQSPMEIR-------------------------------CTEEGAGPGIFRMELG-----------------------------DQR-----------QSISQSQRWCCLQRGCVILGVLGLLAGAGIASWLLVLYLWPAASPSISGTLQEEEMTLNCPGVSREEELLPSLPKTVSFRINGEDLLLQVQVRARPDWLLVCHEGWSPALGMHICKSLGHIRLTQHKAVNLSDIKLNRSQEFAQLSARPGGLVEESWKPSANCPSGRIVSLKCSECGARPLASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPHWVVTAAHCMYSFRLSRLSSWRVHAGLVSH--GAVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVGAVCLPAKEQHFPWGSQCWVSGWGHTDPS-----HTHSSDTLQDTMVPLLSTYLCNSSCMYSGALTHRMLCAGYLDGRADACQGDSGGPLVCPSGD--TWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWIHDTVQVR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3S3-1", "uniprot_id": "TMPS5_HUMAN", "id": "Q9H3S3-1", "name": "Transmembrane protease serine 5", "aln": "--------------------------MSLMLDDQPPMEAQ-------------------------------YAEEGPGPGIFRAEPG-----------------------------DQQ-----------HPISQAVCWRSMRRGCAVLGALGLLAGAGVGSWLLVLYLCPAASQPISGTLQDEEITLSCSEASAEEALLPALPKTVSFRINSEDFLLEAQVRDQPRWLLVCHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSSQEFAQLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSH--SAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPS-----HTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGD--TWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDTAQDSLL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B715-1", "uniprot_id": "A0ACD6B715_DANRE", "id": "A0ACD6B715-1", "name": "", "aln": "MFGSTEGSLGSHDRPHDPLGKTTGSFFAPLLTSLSLCEVKIQRCIQLNGLTAAGVEHLCCDGGELMRESSSCSQEIPNPNNESMSLSRDAVAVIENPVVVRQSFHPESLQVDMLETDQNNHRCLRELQFLHPVSGKVSSRKLVRVFAALCVLCLLGGVVVGVWFIVKFLLKPNLSQSPASLGDTKDTSFCN---VTEDISVTDPRKVFYRISAENSLLEIQLEKLQTWLPVCFERWNSSLGTLVCRQLGYLRLSKHKGVNLTDIGPNYTDGFVQITSEYQSNLESLWRFRGSCSTGKVIALKCFECGTRAKLPRIIGGVEAALGRWPWQVSLYYNNRHICGGSIITNQWIVTAAHCVHNYRLPQVPSWVVYAGIITSNLAKLAQYQGFAVERIIYNKNYNHRTHDNDIALVKLKTPLNFSDTIRPVCLPQYDHDLPGGTQCWISGWGYTQPD-----DVHIPEVLKEAPVPLISTKKCNSSCMYNGEITSRMLCAGYSEGKVDACQGDSGGPLVCQDEN--VWRLVGVVSWGTGCAEPNHPGVYTKVAEFLGWIYDIIESY-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBU1-1", "uniprot_id": "A1ZBU1_DROME", "id": "A1ZBU1-1", "name": "trypsin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYSTKFLWWLMALVAYAGATPT--------------PGDGRIVGGEVATIQEFPYQVSVQLQGRHICGGAIIGIDTVLTAAHCFEDPWSSADYTVRVGSSEHES------GGHVLSLRRVIAHGDYNPQSHDNDLALLILNGQLNFTEHLQPVPLAALADPPTADTRLQVSGWGFQAEESAVSGEVGVSPQLRFVDVDLVESNQCRRAYSQVLPITRRMICAARPGR--DSCQGDSGGPLVGYAAEEGPARLYGIVSWGLGCANPNFPGVYTNVAAFRSWIDEQLDARGWDELLAGWSRLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : .: . **:** .: .:*:*.*: ** **.::: ::*****. . . : * :. : :.::* : *. :.** *:**: *. :**:: : .* *. . . .:: :****. . .. . *: . * *..: *. : :* **:**. *:********** : :* *:**** ***:** ****::** * .** : : ", "identical_positions": 73, "similar_positions": 76, "identity": "12.72%" }, { "cls_id": "homologset.agr.MGI:1933427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04828-1", "uniprot_id": "AK1C1_HUMAN", "id": "Q04828-1", "name": "Aldo-keto reductase family 1 member C1", "aln": "----MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP----GEE--VIPKDENGK--ILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFA--GPPNYPFSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52895-1", "uniprot_id": "AK1C2_HUMAN", "id": "P52895-1", "name": "Aldo-keto reductase family 1 member C2", "aln": "----MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP----GEE--VIPKDENGK--ILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFA--GPPNYPFSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42330-1", "uniprot_id": "AK1C3_HUMAN", "id": "P42330-1", "name": "Aldo-keto reductase family 1 member C3", "aln": "----MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP----GEE--LSPTDENGK--VIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFA--SHPNYPYSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17516-1", "uniprot_id": "AK1C4_HUMAN", "id": "P17516-1", "name": "Aldo-keto reductase family 1 member C4", "aln": "----MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP----GET--PLPKDENGK--VIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLM--DHPDYPFSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70694-1", "uniprot_id": "DHB5_MOUSE", "id": "P70694-1", "name": "Estradiol 17 beta-dehydrogenase 5", "aln": "----MDSKQQTVRLSDGHFIPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVKREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKP----GEN--YLPKDENGK--LIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAYSALGSHREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSEDMKVLDDLNKNIRYISGSSFK--DHPDFPFWDEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VTY2-1", "uniprot_id": "Q9VTY2_DROME", "id": "Q9VTY2-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "----MKLAP-TVKLNNGYEMPILGLGTYNSKD---NEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKY----VDDNTLLPKNEDDV--LQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLAN--CEIKPVTNQVECSPALNQKALTAFCKKNDVTLTGYTPLGKPKP----DIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "id": "Q12458-1", "name": "Aldehyde reductase YPR1", "aln": "MPATLKNSSATLKLNTGASIPVLGFGTWRSVD---NNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIK----DSGVPREEIFITTKLWGTEQRDP--EAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFG--------SANAP-LLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIFT--LPEDDFKTISNLSKVHGTKRVVDMK---WGSFPIFQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "id": "P14065-1", "name": "Glycerol 2-dehydrogenase (NADP(+))", "aln": "MPATLHDSTKILSLNTGAQIPQIGLGTWQSKE---NDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK----DSGVPREEIFVTTKLWCTQHHEP--EVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLG--------STDAP-LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFT--LSTEDFEAINNISKEKGEKRVVHPN---WSPFEVFK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *. * :* :*:**: . : . . . *:. *::***:* .* ** :** **: :. * **:** .:*:* . .*.. ***:****:* * . *. ::. : : *:: ::: . * .:::*****. . : :* . : *. **:* * : : * **:.:.:.: .::.:* . . * :: . : :*** . : : : : * : :.** . .** * .:* *. ::: .:.. : ", "identical_positions": 66, "similar_positions": 100, "identity": "19.58%" }, { "cls_id": "homologset.agr.MGI:1933438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1Q7T3-1", "uniprot_id": "F1Q7T3_DANRE", "id": "F1Q7T3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-GGAVVDTGDSG------VKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELIREFG---VGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQ-------YKYGWRGGFLILGGLLLNCCACGALMRPLLAPKKT--SEVEEKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KETKPKPKLLDFTVFKDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLTILGFIDIFARPTSGIIAGLKWVRPRCVYLFSFAMIFNGIADILGSFAKDYASLVVFCIFFGISYGMVGALQFEVLMAIVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRLL---DATKNYMYVFMLAGCEVVLSALVLAICNLLFIKRKPQQPDPPAKMEMAITETEMEELNKAPKDDQDNGGGAENEKKQAIEPETKTTSKDEVKELESIEVDSIEVENASKKVSGPNGVAVEPESSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BBA0-1", "uniprot_id": "A0A8M2BBA0_DANRE", "id": "A0A8M2BBA0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-GGVALDDGGCK------VKAPDGGWG-WAVLFGCFVITGFSYAFPKAVSVFFKELIREFG---VGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMLVGGLFASLGMILASFATSIIHIYLCTGVITGLGMALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQ-------YEYGWRGGFLILGGILLNCCACGALMRPLVPPKSSEAPGIENAPDDGD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTVKPKPKLLDFSVFRDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLSILGFIDIFARPTCGIIAGLQWVRPRCVYLFSFALIFNGITDLVGSLSKDYTSLVVFCIFFGISYGMVGALQFEVLMAVVGTEKFSSAIGLVLMLEAIAVLVGPPSAGRLL---DHTKKYMFVFLLAGIEVVLSALVLAICNFLCIKKKPEAPDAAAVESGEPVEEKNHSSPPATEEPHTPNGNSE-KPKTDLRPE-------NVTEEPTEEETFLKEEDEKEKT-----ITCSAESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P57787-1", "uniprot_id": "MOT4_MOUSE", "id": "P57787-1", "name": "Monocarboxylate transporter 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-GGAVVDEGPTG------IKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELMHEFG---IGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQ-------DHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQVGGGTEPRGPQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPPQRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLL---DATKVYKYVFILAGAEVLTSSLVLLLGNFFCIG-KRKRPEVTEPEEVASEE-KLHKPPVDVGVDS------------------------------REVEHFLKAEPEKNGE-----VVHTPETSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35910-1", "uniprot_id": "MOT4_RAT", "id": "O35910-1", "name": "Monocarboxylate transporter 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-GGAVVDEGPTG------IKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELMHEFG---IGYSDTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQ-------DHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQASGGAEPHGPQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPSPRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLL---DATKVYKYVFILAGAEVLTSSLVLLLGNFFCIG-KRKRPEVTKPEEVASEEEKLHKPPVDVRVDS------------------------------REVEHFLKAEPEKNGE-----VVHTPETSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15427-1", "uniprot_id": "MOT4_HUMAN", "id": "O15427-1", "name": "Monocarboxylate transporter 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-GGAVVDEGPTG------VKAPDGGWG-WAVLFGCFVITGFSYAFPKAVSVFFKELIQEFG---IGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQ-------DRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPG----SGPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLL---DATHVYMYVFILAGAEVLTSSLILLLGNFFCI---RKKPKEPQPEVAAAEEEKLHKPPADSGVDL------------------------------REVEHFLKAEPEKNGE-----VVHTPETSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "----------------------------------------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETRE--GPSSGYNPNFNAADAILKKNSDQ-VDLDVN-KLTNV-TSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLAN-ISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLY-------KEVGFQWAIRILSFICLTCLICASVLARERTKPVVQPFKSKAEVAKW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFA-DKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIG-KGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF--------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08777-1", "uniprot_id": "MCH5_YEAST", "id": "Q08777-1", "name": "Riboflavin transporter MCH5", "aln": "----------------------------------------------------------------------------------------------------------MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGEN-TSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSS-ESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPHVIE--NSKDGESRWRY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLS-DKFG-RFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIIS-IKTTADYQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF--------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHGPPAR-RKSQQQHEACEMDMERQPTPPDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFN---EGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIG-------NYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACG--VSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMY---DLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS---------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYG-WVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLS------DFGNTRWCLRIIGISCSISVLVAIALLKERNPTPAIGLKSPRAMF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAG--DKFGRANVTIVLTTLLTIYMFAFWIP-AHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWG------------------------------KLKERKTKYDLLLGPGIKKYFLRMVYPMKV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDDINGNTSIS------IEVPDGGYG-WFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQ-------KRGVKWALIAQCIICTSLSTIALMLTRTTHQGLRQHKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIA--DKYGSLTVGMILHLVMAILCWAMWIP-CKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLS--------------------------------------HMSKCLFRYKQLPRRV--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:** * : : :: . . . . . : .: . : . * . . . . : .. * . .: * :* :* * .:. * . : . : . : :. : . : . :: . : . .* * * . . * * : .: . . : : * :: . ", "identical_positions": 17, "similar_positions": 61, "identity": "1.9%" }, { "cls_id": "homologset.agr.MGI:1933527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AM26-1", "uniprot_id": "A0A8I6AM26_RAT", "id": "A0A8I6AM26-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRG-------DDWNDR------EWDRGRERRSRGEYRDYDR-NRRERFSPPRHELSPPQKRMRRDWDEHSS--DPYHSGYDMPYAGGGGGPTYGPPQPWGHPDVHIMQ-HHVLPIQARLGSIAEIDLGVPPPIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTEHDLRILEQ---EEEEEQAGKTGETSKKEEGRAGPAPGD--GERKVNDKDEKKEDGKQAENDSSNDDKTKKPEGDGDKEEKKEEAE--KEAKKS-KKRNRKHSGDDSFDEGSVSESESESESG--------------------QAEEEKEEAEEALKEKEKP----KEE-EREKPKD-------------------------------------TAGLEC---------------------KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPP--------------APTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRVSHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ-ILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQG-YPGKPRN-RMVRGDPRAIVEYRDLDAPDDVDFF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MR6-1", "uniprot_id": "SRRT_MOUSE", "id": "Q99MR6-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRG-------DDWNDR------EWDRGRERRSRGEYRDYDR-NRRERFSPPRHELSPPQKRMRRDWDEHSS--DPYHSGYDMPYAGGGGGPTYGPPQPWGHPDVHIMQ-HHVLPIQARLGSIAEIDLGVPPPIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ---EEEEEQAGKTGEASKKEEARAGPALGE--GERKANDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEEAE--KEAKKS-KKRNRKQSGDDSFDEGSVSESESESEGG--------------------QAEEEKEEAEEALKEKEKP----KEE-EKEKPKD-------------------------------------AAGLEC---------------------KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPP--------------VPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ-ILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGGYPGKPRN-RMVRGDPRAIVEYRDLDAPDDVDFF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXP5-1", "uniprot_id": "SRRT_HUMAN", "id": "Q9BXP5-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRG-------DDWNDR------EWDRGRERRSRGEYRDYDR-NRRERFSPPRHELSPPQKRMRRDWDEHSS--DPYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQ-HHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ---EEEEEQAGKPGEPSKKEEGRAGAGLGD--GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE--KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG--------------------QAEEEKEEAEEALKEKEKP----KEE-EWEKPKD-------------------------------------AAGLEC---------------------KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPP--------------LPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ-ILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGGYPGKPRN-RMVRGDPRAIVEYRDLDAPDDVDFF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I22-1", "uniprot_id": "SRRT_DANRE", "id": "Q66I22-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSREREDRRR--------DDWNDRRPSAR-EWDRGRERRSRGEYRDYDR-GRRERFSPPRHDMSPQQKRMRRDWDDHGG--DPYHGGYDLGYGGGGG-PSYAPPQPWGHPDMHLMQPHHGIPIQARLGNIHDMDLGPPPPVMKTFKEFLISLDDSVDETESVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEAGRRKAEAHSALQNRLGVYMYLMDNNWFESVSLDIERAPQITKILDAAVIKMEGGAENDLRILEQPSEEEEERERLSSGGTPSEPSKRDEPKPAD--TENKPSEEKDKMEEGEESAEKDGEKASAGGSEGE-EKTEKEAPAEPIPEPKKLSKKRKRKHSGD-SEDEASASESESDSDSDSNSHCSEKPSEREREPEEVEEKEEEEEEEGEAADGKEQT----DEQTEREKEKEKK----------------------------------VKDDQPP---------------------RPRPLHRTCSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSEPQPERRFFRRCWVTFDRGVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDDREKLWSQKPREET--------------PTLELPAQNPILKNITDYLIEEVSAEEEELLGSAGGGDSEDGSKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNTCEYPSEDEMPNRCGIIHVRGPIPPNRITLREVSDWQKTFEEKMGPLFSVKENLSEDEAAKMGRKDPEQEVEKFVVANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVVFFNNFLMDAKRPCIPEMKPPPHPGPGQGVLSPG---GLPFPPQGPQGLMGFGQPRPPLMGYG----------GGPPYPPNQYGGGRGNYDNFRGQGGYPGKPRNSRVMRGDPRNIIEYRDLDAPDDVDFF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9K7-1", "uniprot_id": "SRRT_DROME", "id": "Q9V9K7-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRKRRDKFRGERESY-RTERRDDRRPVGGSAGARDEWAERNPFRGGASAGGGGARHRPDYSDYRGPGARPRYGSPVRDLPP-AKRMRPDWGDGDVRANPRFGGYDPYLMQAWNDHYQSMHSAYSHG-------GHAPPVRESIGGGGGDTLTQP--AMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDG--LRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTG----ENKDTEGEP----IERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP-PPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEH-----PGTSK-------------RPESESARGGGGGYRPPMY---------------PPFSAMPYGFGPPMMGGGRGGRNFPPARRE--LPLEHQRRLIGYHDLDAPANSDMFD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:****** **..* *:..*::** *:* :* * * * :* ** . * *:..* :::.* **** **.: . :* ..**: . . . ..:.* * *:: :*. * * * .:*:** : *:.:.::* :::*.:** **:***:::**:********:.****:: :* * :. **.* *:: *::.. : .: :* .:* : ::**:.***:***::.**::*:: : : . : : : * . . . * :: .. :. .: . . : *.. :: * *: **:.:*:. : * *:.* ***.*.*: : *::.:* :* . :.. .* * : * . :**.**:*.*:*:*.:**.*:::** ::*.*:.*::**.:::* ***::** *:** *.********.*:* ***:**:.. *****:**** **** ***::*.****.**: **:: :**:. * . . : :***:*:*********.********* :* *: .**:* :****:*:.***:*::*******:**** **** ************.*** ** *:: :* :: * :*.*: ::: **::* ::* **.* ****** :*****.******************:****:*** :*::**:*** :***:* *.*** :** **..: : .. * ***: **:. ** * . ** :* *: : . * :: *:***** : *:* ", "identical_positions": 348, "similar_positions": 250, "identity": "34.8%" }, { "cls_id": "homologset.agr.MGI:1933532", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MR3-1", "uniprot_id": "S12A9_MOUSE", "id": "Q99MR3-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MASESSPLLAYRLLGEEGAAFPP-----NGAGVSGVPS--------------------SRKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYIILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADATG---SSGIQVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNIPLAPRPGTNASSVPHRHGHFTGFNGSTLRDNLGAGYAEDYTTG---AMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQEDYGFFRDISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGP---SSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGG---SPALSTLFP----PPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPE-RLSRGSSSSAQLHHVDVWPLNLLRPRGGPGYVDVCG-------LFLLQMATILSMVPAWHSAR-LRIFLCLGPREAPG---AAEGRLRALLSQLRIRAEVQEVVWGEGAETGEPE---------------------------------------------------------------------------------------------------------EEEGDFVNGGRGDEEAEALACSANALVRAQQGRGTVGGPGGPEGRDGEEGPTTALTFLYLPRP----------------------------------------------------------------------------PAD-----PARYPRYLALLETLSRDLGPTLLIHGVTPVTCTDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HR0-1", "uniprot_id": "S12A9_RAT", "id": "Q66HR0-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MASENSPLLAYRLLGEEGAAFPP-----NGAGGSGVAS--------------------ARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADVTG---SSGIKVLPQGYGWNLLYGSLLLGLVGGVCALGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNITLAPRPGTNGSSVPPRHGHFTGFNGSTLKDNLGAGYAEDYTTG---AMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFFRDISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGP---SSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGG---SPALSTLFP----PPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPE-RLSRGSGSSAQLHHVDVWPLNLLRPRGGPGYVDVCG-------LFLLQMATILSMVPAWHSAR-LRIFLCLGPREAPG---AAEGRLRALLSQLRIRAEVQEVVWGEGAEAGEPE---------------------------------------------------------------------------------------------------------EEEGDFVNGGRGDEEAEALACSANALVRAQQGRGTGGGPGGPEGRDGEEGPTTALTFLYLPRP----------------------------------------------------------------------------PAD-----PARYPRYLALLETLSRDLGPTLLIHGVTPVTCTDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXP2-1", "uniprot_id": "S12A9_HUMAN", "id": "Q9BXP2-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MASESSPLLAYRLLGEEGVALPA-----NGAGGPGGAS--------------------ARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIATNGAVQGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVLDVFGADATG---PSGLRVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIRLTPRPGPNGSSLPPRFGHFTGFNSSTLKDNLGAGYAEDYTTG---AVMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLAALLTARGGP---SSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPADSTREGS---SPALSTLFP----PPRAPGSPRALNPQDYVATVADALKMNKNVVLARASGALPPE-RLSRGSGGTSQLHHVDVWPLNLLRPRGGPGYVDVCG-------LFLLQMATILGMVPAWHSAR-LRIFLCLGPREAPG---AAEGRLRALLSQLRIRAEVQEVVWGEGAGAGEPEA--------------------------------------------------------------------------------------------------------EEEGDFVNSGRGDAEAEALARSANALVRAQQGRGTGGGPGGPEGGD-AEGPITALTFLYLPRP----------------------------------------------------------------------------PAD-----PARYPRYLALLETLTRDLGPTLLVHGVTPVTCTDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BFP5-1", "uniprot_id": "S12A9_DANRE", "id": "A2BFP5-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MANEHSPLLVHGVYSMMGNAEDSR----GGSAGTGEASNPKTD---------------PRKLNTFFGVMVPTILSMFSIVLFLRTGFVVGHAGLLHGLLMLFVAYFIISLTILSICAISTNGAVEGGGAYFMISRSLGPEFGGSIGLMFYLAKVCACGVYVLGLVEAIMDVFGQDPGSSV-AQGLRVLPQGYWYTVLYSSVVLLLCMLVCLVGAHIYAKASFLILLVVTVSLISIIISPLIVSPQGFNITHTYGNNHSVTVSPS--YTGFNSTTLKNNLGPRYSLDYSTN---TMMSFATVFAVMFTSCTGIMAGANMSGELKNPSESIPKGTIMAVAYTFTVYVLLYLLLSSTCDRSLLLNDYAVFQRVNVWPPFVTIGVYCASLSAAMCSMIGASRILHALALDQLFGLPLAPAAVTSSSGNPWVSVLYTWALVQCTLFAGQLNVIAGIVTVFYLLAYAAVDLACLALEWASAPNFRPTFQFFSWHTCLLGIISCVVMMFVINPVYSSASIVLLLLLLLFLHYRSPT---SSWGYISQALIFHQVRKYLLMLDSRKDHVKFWRPQVLLMVSNPRSSCQLICFVNQLKKGGLFVLGHVQIGDLDVLPADPVQPQYNFWLSLVDKLGVKAFVDLTLSPSVRQGTQHLLRITGLGGMKPNTLVLGFYDNSYPEDYFLQDPVFCKGDRSEGDNFGVDLPSLQAHFP----PVRHAESPRALQPQEYVSIIQDAIKMGKNICLARYFFQLPPESKGATYMWGKDSMDTIDVWPTNLLTP-GSASYADVGS-------LFLLQMACVLNMASGWRRAR-LRIFVCVESESEDQGWLAKEEQFRELLGKLRIRAAIKIVAWDNVARMVRGP-----------------------------------------------------------------------------------------------------------------NTESQPVSEDFLCAVNGLLKEHS-------------------STAAVRFLYLPDP----------------------------------------------------------------------------PSS-----CELSQQYLTQLDTLTRDLGPTLLIHGVTPVTCTEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ75-1", "uniprot_id": "Q9VJ75_DROME", "id": "Q9VJ75-1", "name": "Solute carrier family 12 member 9", "aln": "----------------MSASAEQETAPIANSRSGRTGSVFRSFGSLFGGSQNSGDRPHTPQDGDGYVEFGMQDPDRSGRTLGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGILLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFG--PRGHF-VSGDSHLPDGDWWRFLTSSMINTLQLLVCLVGAALFAKTSVIILATVTVCLFATYFSFLFVGATNNTIP-VPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGRDYTSNG--KQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTPYFTMQNNYLFLMPVNLWPPFTAIGILTATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTWKGNPIAAVAVSWCLVECILLIGSFNIIAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCLVGLLGTLIMMFVINFIYASSCIILCLILVIALHLFSPATQAAQWGSISQALMFHQVRKYLLMLDPRKDHVKFWRPQILLLVSSPRSCCPLVDFVNDLKKSGLYIIGHVKLGDFKGIEDAEDNQQ---WWSFLDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAMKPNTIILGFYDSEAPRDFFQNGSSPYKTDDFN---------NGEIQNF----PIRRDGDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQRLDKN-----FISMSKHVKYIDVWPINIFNPTSGDP-FDMVS-------LFMMQLAVIM--LAKWKHLR-VRIFLCEANDERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSRD-----------------------------------------------------------------------------------------------------TDFSRHARTLKQFTAQADNVVLEDDDEVGEETLNRSLLYMQRANQIIRERSDQTALSFIYLAAP----------------------------------------------------------------------------PKLSAPDFAQRSASYMELLTELTADLPPTILVHGVSTVTSTTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38329-1", "uniprot_id": "VHC1_YEAST", "id": "P38329-1", "name": "Vacuolar cation-chloride cotransporter 1", "aln": "MVSRFYQIPGTHRPSSAISSSNESSSLLSARRISQTYFNYQATPECQKVSSKYDPDNPN------------------KDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGTVRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLPRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIRSP---------------FTEGGISYTGPSWQTFHDNLLPHLTKGAAGSLLKGKETFNDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDEVQIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFAHS------PLYSLIFTWILTQLCLFS-DVNKIATFITMTFLMTFVVMNLACFLLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFSPP---KSWGDVSQSLIYHQVRKYLLRLR--QDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKGGLYILGHVAVTADFPKQLNELKTQQKAWMKIRDMAAIKAFVQVGTGPSLIWGIRNVFIGSGLGGMKPNITVVGFFDLESYRKHIPQSRSQNNLQKQVEIKATVPRSTCSDVKINVPLPTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGFKNLEIP----NKRDSCFPKKTIDLYPIQMCGKVEAKGDQPAAITTNFDTYTLILQLAAILVTVPEWKRTHSLRVILFVEQEYHRT---NETQRMKKLLQVLRIDAEVLVVSLDQFRVYNTIVKGDPIVFDYVNSKLADNEWWKDLVEARDTLKPKRRFSTIEPQTIAKQFTQSRKYTSGVQKLGVSFTMNTRMPTNRIDTPCESEDSDLDTDLTSIRDAFSASTNISVGKDLTTKSKTGSDRTNLLVKNLQSDVSTQSLRPVFSSNTLPRTRVVEDGTGEQPTLIPIAEPDLSNGNGTGSGIGNGNKLKKPVLPELSPCCSKDSLVTAMQNLGFNDLPSTAQHLVLNDVMTQMSKSSDLIFSTLPVPALGTHEDHDASLQYVEDLDIWLEGLPPCMLINSQTMTVTTAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :. : . . : . .*.*: **. *. *.::* ::*:* *:::*: *: : ::::* * :* *:.**:***::.***.*:****:** *.***** :*::.:* ..: * * :: :* . ** * . .::: * *. :*: :::. : : :: .: : .* : .. :** . *:::** . . : . * *.*:* . :**:***.**.**:.**.:** **: .: :** * :: : . : : : .: :. . :* ::: : : .::*:: :*.*:: *::: . * :: :* *.: *: ..* :* . :: ::::: . :*:*: : :.****** *. *. :* :* :: *:::. :. :: :* : . . .** :**:*::******** * ::::*:****:**:*..** . *: : *.***.**:::*** : : * * .: * :***.:: . *: * :::: :*:*.**** ::**:* ...: . : . * . .. *::* : * * .*: :.: * . :*::* :: . :::*:* :: . *: : :*::: :: ::: : : :: . : : . :: :. * * *: * .* * :*::. : .. * *", "identical_positions": 174, "similar_positions": 280, "identity": "14.85%" }, { "cls_id": "homologset.agr.MGI:1933533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MH3-1", "uniprot_id": "HEPC_RAT", "id": "Q99MH3-1", "name": "Hepcidin", "aln": "-----MALSTRIQAAC-LLLLLLASLSSGAYLRQQTRQTTALQP-WHGAESKTDDSALLMLKRRKRDTNFPICLFCCKCCKNSSCGLCCIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ21-1", "uniprot_id": "HEPC_MOUSE", "id": "Q9EQ21-1", "name": "Hepcidin", "aln": "-----MALSTRTQAAC-LLLLLLASLSSTTYLHQQMRQTTELQP-LHGEESR-ADIAIPMQKRRKRDTNFPICIFCCKCCNNSQCGICCKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81172-1", "uniprot_id": "HEPC_HUMAN", "id": "P81172-1", "name": "Hepcidin", "aln": "-----MALSSQIWAACLLLLLLLASLTSGSVFPQQTGQLAELQP-QDRAGAR-ASWMPMFQRRRRRDTHFPICIFCCGCCHRSKCGMCCKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61516-1", "uniprot_id": "HEPC1_DANRE", "id": "P61516-1", "name": "Hepcidin-1", "aln": "MKLSNVFLAAVVILTCVCVFQITAVPFIQQVQDEHHVESEELQENQHLTEAEHRQTDPLVLFRTKRQSHLSLCRFCCKCCRNKGCGYCCKF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:: :* :: : * :: : ** . :. . . * :*::::.:* *** **... ** ** ", "identical_positions": 17, "similar_positions": 25, "identity": "18.68%" }, { "cls_id": "homologset.agr.MGI:1933546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925I4-1", "uniprot_id": "TS1R2_MOUSE", "id": "Q925I4-1", "name": "Taste receptor type 1 member 2", "aln": "MGPQARTLHLLFLLLHALPKPVMLVGNSDFHLAGDYLLGGLFTLHANVKSVSHLSYLQVPKCNEYNMKVLGYNLMQAMRFAVEEINNCSSLLPGVLLGYEMVDVCYLSNNIQPGLYFLSQIDDFLPILKDYSQYRPQVVAVIGPDNSESAITVSNILSYFLVPQVTYSAITDKLRDKRRFPAMLRTVPSATHHIEAMVQLMVHFQWNWIVVLVSDDDYGRENSHLLSQRLTNTGDICIAFQEVLPVPEPNQAVRPEEQDQLDNILDKLRRTSARVVVIFSPELSLHNFFREVLRWNFTGFVWIASESWAIDPVLHNLTELRHTGTFLGVTIQRVSIPGFSQFRVRHDKPEYPMPNETSLRTTCNQDCDACMNITESFNNVLMLSGERVVYSVYSAVYAVAHTLHRLLHCNQVRCTKQIVYPWQLLREIWHVNFTLLGNQLFFDEQGDMPMLLDIIQWQWGLSQNPFQSIASYSPTETRLTYISNVSWYTPNNTVPISMCSKSCQPGQMKKPIGLHPCCFECVDCPPGTYLNRSVDEFNCLSCPGSMWSYKNNIACFKRRLAFLEWHEVPTIVVTILAALGFISTLAILLIFWRHFQTPMVRSAGGPMCFLMLVPLLLAFGMVPVYVGPPTVFSCFCRQAFFTVCFSVCLSCITVRSFQIVCVFKMARRLPSAYGFWMRYHGPYVFVAFITAVKVALVAGNMLATTINPIGRTDPDDPNIIILSCHPNYRNGLLFNTSMDLLLSVLGFSFAYVGKELPTNYNEAKFITLSMTFSFTSSISLCTFMSVHDGVLVTIMDLLVTVLNFLAIGLGYFGPKCYMILFYPERNTSAYFNSMIQGYTMRKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TE23-1", "uniprot_id": "TS1R2_HUMAN", "id": "Q8TE23-1", "name": "Taste receptor type 1 member 2", "aln": "MGPRAKTISSLFFLLWVLAEPAE---NSDFYLPGDYLLGGLFSLHANMKGIVHLNFLQVPMCKEYEVKVIGYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNVQPVLYFLAHEDNLLPIQEDYSNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSADHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARR-DICIAFQETLPTLQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLRQNFTGAVWIASESWAIDPVLHNLTELRHLGTFLGITIQSVPIPGFSEFREWGPQAGPPPLSRTSQSYTCNQECDNCLNATLSFNTILRLSGERVVYSVYSAVYAVAHALHSLLGCDKSTCTKRVVYPWQLLEEIWKVNFTLLDHQIFFDPQGDVALHLEIVQWQWDRSQNPFQSVASYYPLQRQLKNIQDISWHTINNTIPMSMCSKRCQSGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYECQACPNNEWSYQSETSCFKRQLVFLEWHEAPTIAVALLAALGFLSTLAILVIFWRHFQTPIVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTICISCIAVRSFQIVCAFKMASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGMLATGLSPTTRTDPDDPKITIVSCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLCTFMSAYSGVLVTIVDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMRRD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:*: **:** .*.:*. ****:*.*********:****:*.: **.:**** *:**::**:***************** ************:*****:***:** ****:: *::*** :***:* .:************.:**:*:** **:**:*****:*:**** ****:***.*** **********:**:****:****.* ***:*.:**.:*::. ********.**. :*** : .**:::* .*:***::::*****:***:*:*::**.**** **** ********************** *****:*** *.*****:** :. * ..** ****:** *:* * ***.:* *******************:** ** *:: ***::*******.***:******.:*:*** ***:.: *:*:****. *******:*** * : :*. *.::**:* ***:*:***** **.** ***:*:* *****:** ***:**:: **::* :**.. ***:.: :****:*.******.***.*::******:******:*********:*************. **:*: :********.* :*:****:*.:**::*:***:********.**** *:* **.:*:**:**** :****.:*:.:*. .**** :.* *******:* *:**:*****.******:******:******:******************** ****:*******.:.******:********:***.*******************.*************:.", "identical_positions": 586, "similar_positions": 182, "identity": "69.51%" }, { "cls_id": "homologset.agr.MGI:1933547", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923K1-1", "uniprot_id": "TS1R3_RAT", "id": "Q923K1-1", "name": "Taste receptor type 1 member 3", "aln": "MPGLAILGLSLAAFLELGMGSSLCLSQQFKAQGDYILGGLFPLGTTEEATLNQRTQPNGILCTRFSPLGLFLAMAMKMAVEEINNGSALLPGLRLGYDLFDTCSEPVVTMKPSLMFMAKVGSQSIAAYCNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYSASMDRLSDRETFPSFFRTVPSDRVQLQAVVTLLQNFSWNWVAALGSDDDYGREGLSIFSGLANSRGICIAHEGLVPQHDTSGQQLGKVVDVLRQVNQSKVQVVVLFASARAVYSLFSYSILHDLSPKVWVASESWLTSDLVMTLPNIARVGTVLGFLQRGALLPEFSHYVETRLALAADPTFCASLK-AELDLEERVMGPRCSQCDYIMLQNLSSGLMQNLSAGQLHHQIFATYAAVYSVAQALHNTLQCNVSHCHTSEPVQPWQLLENMYNMSFRARDLTLQFDAKGSVDMEYDLKMWVWQSPTPVLHTVGTFNGTLQLQHSKMYWPG--NQVPVSQCSRQCKDGQVRRVKGFHSCCYDCVDCKAGSYRKHPDDFTCTPCGKDQWSPEKSTTCLPRRPKFLAWGEPAVLSLLLLLCLVLGLTLAALGLFVHYWDSPLVQASGGSLFCFGLICLGLFCLSVLLFPGRPRSASCLAQQPMAHLPLTGCLSTLFLQAAEIFVESELPLSWANWLCSYLRGPWAWLVVLLATLVEAALCAWYLMAFPPEVVTDWQVLPTEVLEHCRMRSWVSLGLVHITNAVLAFLCFLGTFLVQSQPGRYNRARGLTFAMLAYFIIWVSFVPLLANVQVAYQPAVQMGAILFCALGILATFHLPKCYVLLWLPELNTQEFFLGRSPKEASDGNSGSSEATRGHSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925D8-1", "uniprot_id": "TS1R3_MOUSE", "id": "Q925D8-1", "name": "Taste receptor type 1 member 3", "aln": "MPALAIMGLSLAAFLELGMGASLCLSQQFKAQGDYILGGLFPLGSTEEATLNQRTQPNSIPCNRFSPLGLFLAMAMKMAVEEINNGSALLPGLRLGYDLFDTCSEPVVTMKSSLMFLAKVGSQSIAAYCNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYSASMDRLSDRETFPSFFRTVPSDRVQLQAVVTLLQNFSWNWVAALGSDDDYGREGLSIFSSLANARGICIAHEGLVPQHDTSGQQLGKVLDVLRQVNQSKVQVVVLFASARAVYSLFSYSIHHGLSPKVWVASESWLTSDLVMTLPNIARVGTVLGFLQRGALLPEFSHYVETHLALAADPAFCASLN-AELDLEEHVMGQRCPRCDDIMLQNLSSGLLQNLSAGQLHHQIFATYAAVYSVAQALHNTLQCNVSHCHVSEHVLPWQLLENMYNMSFHARDLTLQFDAEGNVDMEYDLKMWVWQSPTPVLHTVGTFNGTLQLQQSKMYWPG--NQVPVSQCSRQCKDGQVRRVKGFHSCCYDCVDCKAGSYRKHPDDFTCTPCNQDQWSPEKSTACLPRRPKFLAWGEPVVLSLLLLLCLVLGLALAALGLSVHHWDSPLVQASGGSQFCFGLICLGLFCLSVLLFPGRPSSASCLAQQPMAHLPLTGCLSTLFLQAAETFVESELPLSWANWLCSYLRGLWAWLVVLLATFVEAALCAWYLIAFPPEVVTDWSVLPTEVLEHCHVRSWVSLGLVHITNAMLAFLCFLGTFLVQSQPGRYNRARGLTFAMLAYFITWVSFVPLLANVQVAYQPAVQMGAILVCALGILVTFHLPKCYVLLWLPKLNTQEFFLGRNAKKAADENSGGGEAAQGHNE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTX0-1", "uniprot_id": "TS1R3_HUMAN", "id": "Q7RTX0-1", "name": "Taste receptor type 1 member 3", "aln": "MLGPAVLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVASEAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLN--------HHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDPVKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFVESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGCYNRARGLTFAMLAYFITWVSFVPLLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFLGGGPGDAQGQNDGN-TGNQGKHE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *::**** *:*. * *:.******:: :***:******** :*** *..**:*.. *.***. **: *:*********** * ********************:**.****:**.**:.**************************::***************.***: ** ****************** *.. ***:*.***********:***:******.** :************ :...:**** ***:*****.****:****.:*.::**.*** **********:******** **.:*::*********** * **.:**:*:****:**:**::* * .*** *:* **.:** * ***:*:** *** *:.******************.* * ..: * **********::*:. .*.*:**:.*.********:****...* ** ** ***:*: :: *: * ** ***:*****::*******************:*****::***::** *.:*:****:** *: **.:*******.** *****.*.***.****** **: **********. ****:****.*********:* .* ******::***************** ***********: *.. *** ********* :**.***:***:********** :****.* **: *****:**.* *** ************:**** **************** *************. :*******:*.*.****.:****:**:*: * *** ***** .. .* . *.*. . :*: *", "identical_positions": 607, "similar_positions": 156, "identity": "70.5%" }, { "cls_id": "homologset.agr.MGI:1933548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MR0-1", "uniprot_id": "ACL6B_MOUSE", "id": "Q99MR0-1", "name": "Actin-like protein 6B", "aln": "---MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEG-GGLELEGEKEKKGKIF--HIDTNALHVPRDGAEVMSPLKN-GMIEDWECFRAILDHTYSKHVKSEPN-LHPVLMSEAPWNTR---AKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEP---------VREGAPPNWKKKEKLPQVSKSWHNYMCN-----EVIQDFQASVLQVSDSPY------------------------DEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGLFD------PSNVKG--------------------------------LSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86173-1", "uniprot_id": "ACL6B_RAT", "id": "P86173-1", "name": "Actin-like protein 6B", "aln": "---MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEG-GGLELEGEKEKKGKIF--HIDTNALHVPRDGAEVMSPLKN-GMIEDWECFRAILDHTYSKHVKSEPN-LHPVLMSEAPWNTR---AKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEP---------VREGAPPNWKKKEKLPQVSKSWHNYMCN-----EVIQDFQASVLQVSDSPY------------------------DEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGLFD------PSNVKG--------------------------------LSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94805-1", "uniprot_id": "ACL6B_HUMAN", "id": "O94805-1", "name": "Actin-like protein 6B", "aln": "---MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEG-GGLELEGDKEKKGKIF--HIDTNALHVPRDGAEVMSPLKN-GMIEDWECFRAILDHTYSKHVKSEPN-LHPVLMSEAPWNTR---AKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEP---------VREGAPPNWKKKEKLPQVSKSWHNYMCN-----EVIQDFQASVLQVSDSPY------------------------DEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGLFD------PSNVKG--------------------------------LSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6U2-1", "uniprot_id": "A0ACD6B6U2_DANRE", "id": "A0ACD6B6U2-1", "name": "", "aln": "---MSGGVYGGDEVGALVFDIGSFSTRAGYAGEDCPKADFPTTIGVNAEEEGPADMGVEQE-SNSGRSY--YIDTTALHVPRAGVELISPLKN-GMIEDWDAFQAIIDHIYSKHIKSEPA-LHPVLMSEAPWNSR---AKREKLTELIFEHYNIPAFFLCKTAVLTAFANGRATGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRELFQEMNIDTVPSYMIASKEP---------VREGAPAMWTKKDKLPPVSKSWHTFMCN-----EVIQDFQASVLQVSDSPY------------------------DEQVAAQMPTVHYEMPSGYSTDFGAERLRIPEGLFD------PSNVKG--------------------------------LSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTERLNRELSQKAPPSMRLKLIACNSSIERRFSSWIGGSILASLGTFQQ-MWISKQEYDEGGKQSVERKCP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P80428-1", "uniprot_id": "ARP4_YEAST", "id": "P80428-1", "name": "Actin-related protein 4", "aln": "MSNAALQVYGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEG------------NKKIF--SEQS--IGIPRKDYELKPIIEN-GLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNST---ENRKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKSTRRNFIAGKFINHLIKKALEPK--EIIPLFAIKQRKPEFIKKTFDYEVDKSLYDYANNRGFFQECKETLCHICPTKTLEETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEE--LFLPKEDDIPANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKVTPTEEKEQEAVSKSTSPAANSADTPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVDLRATLAHNVVLTGGTSSIPGLSDRLMTELN-KILPSLKFRILTTGHTIERQYQSWLGGSILTSLGTFHQ-LWVGKKEYEEVGVERLLNDRFR---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12406-1", "uniprot_id": "ARP7_YEAST", "id": "Q12406-1", "name": "Actin-related protein 7", "aln": "---------MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGG-----------EAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPE-ELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQK----RSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKECYQFAEYLFKPQLISDKFSPEDGLGP----LMAKSVKKAGASINSMKANTSTNPNGLG-----------TSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELS-IRFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*:. **. . *::. : *:. :*: : : * : * . *: . :.. *: :*: . ...: .. * ::: . * :: *: :: :. . : . ::: *:.. :*:* * .. *: ** .:.:. :. :.*.*:. :: : : : .: : : : : .:. : . : :. :. :. : : : . : .*: ... * * :* . . :* . :: . * .*::**..: : *: :*: **. *. :: :: ::*: . *:*. ::.* :: * .*::*: : . ", "identical_positions": 44, "similar_positions": 145, "identity": "8.49%" }, { "cls_id": "homologset.agr.MGI:1933549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3URD3-1", "uniprot_id": "SLMAP_MOUSE", "id": "Q3URD3-1", "name": "Sarcolemmal membrane-associated protein", "aln": "MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK-VTHGCIVSTIKLFLPDGMEARLRS-DVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVR-LEHLQEKTLKECSSLG-IQVDDFLPKINGSTEK-EHLLSKSGGDCTFIHQFLECQKK------------------LMVQGHLT---KVVEESKLSKE----NQAKAKESDLSDTLSPSKEKSSDDTT-DAQMDEQDLNEPL-AKVSLLKDD-LQGTQSETEAKQDIQHLRKELVEAQELARTSKQKCFELQ-ALLEEERKAYRNQVEESAKQIQVLQ---VQLQKLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLRQAAAEAVSERDTDFVSLQEELKKVRAELEGWRKAASEYENEIRSLQSSFQLRCQQCEDQQREEATRLQG-ELEKLKKEWDVLETECHSLKKENVLLSSELQR-------------------------QEKELHN-SQKQSFELTSDLSILQMTRKELEKQVGSLKEQHLRDAADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKDNLKLLREKGNNKPWP-WMPMLAALVAVTAMVLYVPGLARASP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C219-1", "uniprot_id": "SLMAP_RAT", "id": "P0C219-1", "name": "Sarcolemmal membrane-associated protein", "aln": "MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVVTHGCIVSTIKLFLPDGMEARLRSDDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELVALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLREMNERTQEELRELANKYNGAVNEIKDLSDKLKAAEGKQEEIQQKGQAEKKELQAKIDDMEEKEQELQAKIEALQADNDFTNERLTALQVVRLEPLQEKTLKECSSLGGIQVDDFLPKINGSTEKEERLLSKSGGDCTFIHQFIECQKKK-----------------LMVQGHLT---KVVEESKLSKEE---NQAKAKESDLSDTLSPSKEKSSDDTTDDAQMDEQDLNEPL-AKVSLLKDDDLQGTQAETEAKQDTQHLRKELVEAQELARASKQKCFDLQAALLEEERKAYRNQVEESAKQIQVLQV--VQLQRLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLHQAAAKAVSERDTDFMSLQEELKKVRAELEGWRKAASEYEEEIRSLQSTFQLRCQQCEVQQREEATRLQGGELEKLKKEWDVLENECRSLKKENVLLSSELQR-------------------------QEKELHNNSQKQSLELTSDLSILQMTRKELENQMGSLKEQHLRDEADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKDNLKLLREKGNNKPWP-WMPMVAALVAVTAMVLYVPGLARASP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14BN4-1", "uniprot_id": "SLMAP_HUMAN", "id": "Q14BN4-1", "name": "Sarcolemmal membrane-associated protein", "aln": "MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK-VTHGCIVSTIKLFLPDGMEARLRS-DVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVR-LEHLQEKTLKECSSLE-------------------HLLSKSGGDCTFIHQFIECQKK------------------LIVEGHLT---KAVEETKLSKE----NQTRAKESDFSDTLSPSKEKSSDDTT-DAQMDEQDLNEPL-AKVSLLKDD-LQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQ-ALLEEERKAYRNQVEESTKQIQVLQ---AQLQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQG-ELEKLRKEWNALETECHSLKRENVLLSSELQR-------------------------QEKELHN-SQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGNNKPWP-WMPMLAALVAVTAIVLYVPGLARASP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B800-1", "uniprot_id": "A0ACD6B800_DANRE", "id": "A0ACD6B800-1", "name": "Sarcolemmal membrane-associated protein", "aln": "MPSALAVFSCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEVLSGDIIQFGVDVTENTRK-VTHGCIVSTIKLFLPDGMEARRRS-DVVPAPLPLAIDKVSANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLASTQEASESSWQALIDEDRLLSRLEVMGNQLQAYSKNQTEDGIRKELVALTEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLREMNERTQEELRELANKYNGAVNEIKDLTEKIKLAEDKHEELTQKGLNEKKELQMRIEEMEEKEQALQARIEALQADNDFTNERLTALQVR-LEQLQEKSIKENNSLD-------------------HFLLKSGGDCTLIQQYIECQSVRQLKEAVDSSINKLSNFDEVIDAHLQNNQTTVDNSLPSPDRLKENQIDAKECDMSDTLSPSKEKSSDDTS-DGQMDEQELNEPQ-NRVSLLKEM--DRSLEAGDTEQVIPHIHRELQEAQELANTGKQKCLELQ-AMLEEERKTNRQQTEESAKQIRFLQ---TQLAKLQTDMEALREQRENTITTTREELYSAQEEILVLRHAMEAATAEREREITALQGDLSIVTAELDKWRQTAAKYEVEISNLQASFQLQS-----QHQERASQLQG-ELEKLQADCSGLQNECDSLRAEKSTLMQKLNR-------------------------LEEELDS-SRERSATLSSNLNALEKSQGDLENKLGSIQDQHQQDASKLKIQLAQAESRTRDLQKEYDDTQSLLSDLRQRYEQTEQEKRSINDELEQCKVNLKLLQDKGSNSGWMPWMPVVAAVVAVTAVVLY-PSLSKSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B8Z6-1", "uniprot_id": "A0A8M2B8Z6_DANRE", "id": "A0A8M2B8Z6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEQKLKDPI-NKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELQ-GLLEEEKRANKQQAEESAKQMKVLQ---TQLQKLQEEMENLRDQKDSAVFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQASHLQQN-----QQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDS-SKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLE----QSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERLRLMQDKDNHLSLL--QPILAVAIGLVLALLY-WCLGPLW-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03944-1", "uniprot_id": "VPS64_YEAST", "id": "Q03944-1", "name": "Vacuolar protein sorting-associated protein 64", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVELEKRRRPPPQLQHSPYVRDQSNSQGMTKTPETSPPKRPMGRARSNSRSSGSRSNVDIDQYTIPPGLDLLPTASSPPSVHQVSQQQQLSPILANKIRSPFENQSQDQNDNSIDPTPAGQVTIPVEAVSPPA-----LDELSKFQNGSTETLFRTGSPRKKHTHIIILKSLNATFETKFLVVPFKPDGLKLGRPVTNSVNKNNS----GSKRDLFS---------------------------------------------------------------------------------------QQVRPDNGNFDSRVLSRNHACLSCDPTSGKIYIRDLKSSNGTFVNGVKIRQNDVELKVGDTVDLGTDIDSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQDHTNKNNGNSTNINGIKIDRGHHNQHIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSGIFINNSAGTSINLINMIKTLTTELSLEKQELEKLHSMQNFMQNYTINLDFINKHMIDMNEKHLLKLSTALQKTLSE-------------------------NNDALLKESEDQLKEIKQQNNKVKSACSLKEKQNHEKLQELESELRELNLQIEEERGKNLVLTQSNFNGGINNDNNAKVKQNDSREEKKDTEDTLISTEELGVVEGKRTRVSKGMLFGVVAISFGLVATAVKQLPQ-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06001-1", "uniprot_id": "FAR10_YEAST", "id": "Q06001-1", "name": "Factor arrest protein 10", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGPGPEINKEEHPSSPGKKQITYNSIPKNANLIDGS-------TNSSKRPIEKYDKRIAD-------------PTKSYFP-------------------HSISRT--PRRKYTYILVLTSLNGTFESKHVVIPFKPDGLKLGRPVANSNSSSSSSLRGGKRVDSHTF--------------------------------------------------------------------------------------SQVRSDNGNFDSRVLSRNHALLSCDPLTGKVYIRDLKSSNGTFINGQRIGSNDVEIKVGDVIDLGTDIDTKIEHRKISATVEELFVQPLLESP------IFENEDSDD------------------------------------CHTITEKEEAAAITSHIYGDSNNLELEEVILGSDTEILSGIFINNCIGTSPTLSNIIKTLAMEIPFSKCDNFKLQSMENFLINYTTHLEYTNKLLVEKNDQQLVKLQNGLRRKLSG-------------------------KYEKIIEQNRNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIEDLKTRLEVERYKNSQMMKKNKQK--EQELSTASKKKTTEHDTRGVPG--MNPKGTDKFSIKNTLCNHFTLLTFGTISIGIIAIVFKILSPN----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*:.. :. : : . : :: . : . : * .:: . : : : : : : * : : . : : :: . : :. . . : : : * * . . : . ...: : .: : :.: .. : .*: . : : :. . . : ... . * . . : ..: . ", "identical_positions": 7, "similar_positions": 83, "identity": "0.77%" }, { "cls_id": "homologset.agr.MGI:1933621", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54772-1", "uniprot_id": "SMRD2_RAT", "id": "O54772-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "aln": "MSGRGAGGFP------LPPLSPGGGAVAAALGAPPPPAGPGMLPNPALRGPGPSGGMGVPGAAAFRPMGPAGPAAQYQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKADGDNSGTAGTPGGTPAADKVASWELRVEGKLLDD-----PSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMP-TTQETDGFQVKRPGDLNVKCTLLLMLDHQP--PQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYIN-----------------------------CNRYFRQIFSCGRLRFSEIPMKLAGLLQHP--------DPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLAST---TNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTEPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQ----QRRQELEQVLGIRLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JR8-1", "uniprot_id": "SMRD2_MOUSE", "id": "Q99JR8-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "aln": "MSGRGAGGFP------LPPLSPGGGAVAAALGAPPPPAGPGMLPSPALRGPGPSGGMGVPGAAAFRPMGPAGPAAQYQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKADGDNAGTAGTPGGTPAADKVASWELRVEGKLLDD-----PSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMP-TTQETDGFQVKRPGDLNVKCTLLLMLDHQP--PQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYIN-----------------------------CNRYFRQIFSCGRLRFSEIPMKLAGLLQHP--------DPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLAST---TNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTEPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQ----QRRQELEQVLGIRLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92925-1", "uniprot_id": "SMRD2_HUMAN", "id": "Q92925-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "aln": "MSGRGAGGFP------LPPLSPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFRPMGPAGPAAQYQRPGMSPGNRMPMAGLQVGPPAGSPFGAAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGTAGTPGGTPAGDKVASWELRVEGKLLDD-----PSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMP-TTQETDGFQVKRPGDLNVKCTLLLMLDHQP--PQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYIN-----------------------------CNRYFRQIFSCGRLRFSEIPMKLAGLLQHP--------DPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLAST---TNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQ----QRRQELEQVLGIRLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYG2-1", "uniprot_id": "BAP60_DROME", "id": "Q9VYG2-1", "name": "Brahma-associated protein of 60 kDa", "aln": "MSQRFAPGQAPVQSRYQPPPPAPGMRPYPPPGASFPPRGFPLHPNTTQPVPGTANVAGVPGVPGVP--GVPGPS-LLQRAAQQPGFQSSLRGTGAG---GGGVGSGGGSKRSNESRSLGGGGSKSDFATAK----------KKKKLAEKILPQKVRDLVPESQAYMDLLTFERKLDATIMRKRLDIQEALKRPMKQKRKLRIFISNTFYPSKEP-TNDGEEG---------AVASWELRVEGRLLEDGKGDPNTKIKRKFSSFFKSLVIELDKELYGPDNHLVEWHRTH-TTQETDGFQVKRPGDRNVRCTILLLLDYQP--LQFKLDPRLARLLGVHTQTRPVIISALWQYIKTHKLQDAHEREYIN-----------------------------CDKYLEQIFSCQRMKFAEIPQRLNPLLHPP--------DPIVINHFIESG-AENKQTACYDIDVEVDDTLKNQMNSFLMST---ASQQEIQGLDTKIHETVDTINQMKTNREFFLSFAKDPQMFIHRWIISETRDLKLMTDVAGNPEEERRAEFYYQPWTHEAVSRYFFTKVN----QKRAELEQALGIRNG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53628-1", "uniprot_id": "SNF12_YEAST", "id": "P53628-1", "name": "Transcription regulatory protein SNF12", "aln": "MSKVMK--------------PSNGKGSRKSSKAATPDTKNFFHAKKKDPVNQDKANNASQITPTVPHSHPSDMVIPDHLAELIP-ELYSFQQLVDSEKRLDHFIHLRNLHMKRMVAQWERSKLSQEFLYPHLNFPNVKFLRIFISNVSENQPWQMDTNNEADLMALENATWTMRIEGRLLDNVQANDPAREKFSSFIESIVVDFKNKENDNVPSTKFNAAPEENATEGPSDKKLNLNLPLQFSLPNG--DNSTTTNTDQNNATMGEETAKKDMSSTTPKLESVKWQYDPNNPVDFDGLDIKRVGSENVECTISILRKSSPEEPFMSYSPQLTAIIGLKSGTSHDAIFSIYKYIHLNELLTNDESAFENLMGNRNNHNSNTSTSKMLDAASSQVSIVKLDTQLITLLPSSLKESSPDTMKLTDLLSLINSTHLLPLQPIEIDYTVRVDKASTYGELVLDIEVPDVNALKFNN-TQRESQ---IGAAELNENARELEQIKPKIALQDKEITSVLSNLHESNKRYRFFKKISEDPVKALNECIASTSNALKVLSGDEGYNEDMVRRANFYKENEA--MLRENIEVILSNGRM", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25632-1", "uniprot_id": "RSC6_YEAST", "id": "P25632-1", "name": "Chromatin structure-remodeling complex protein RSC6", "aln": "---------------------------------------------------------MVTQTNPVPVTYPTDAYIPTYLPDDKVSNLADLKKLIEMDSRLDLYLTRRRLDTSINLPTNTKTKDHP---------PNKEMLRIYVYNTTESSPRSDSGTPADS----GKTTWTLRIEGKLLHESAN---GKHPFSEFLEGVAVDFKRLKPLGMGKKRKR------------DSSLSLPLNLQQPEYND-------QDSTMGDNDNGEDEDSAEAESREEIVDALEWNYDENNVVEFDGIDIKRQGKDNLRCSITIQLRGVDG-GKVQYSPNLATLIGMQTGSVNDAVYSIYKYILINNLFVTEQTEAQD------------GSNDAEDSSNENNNKNGAGDDDGVEGSTPKDKPELGEVKLDSLLQKVLDTN-AAHLPLMNVVQTVNKLVSPLPPIILDYTIDLSKDTTYGATTLDVDVSHILHQPQPQPNLQKEEETDAEDTAKLREITKLALQLNSSAQKYQFFHELSLHPRETLTHYLWSSKQNELVLQGDQYFNEDAARTSDIYSNNNNDRSLMGNISLLYSQGRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. . : . . : * . :: ::: : : . . . : : :.. . . * :: :. . . . . : . . ::*: . : **:::** *. *:.*:: : . .*.*: ::*::: : : ::: ** ::* .: : . . . :* ** *: . * : . . . . : : .: : . .. : : . : :.. ...: . : : .: . : . : ::. . ", "identical_positions": 21, "similar_positions": 114, "identity": "3.57%" }, { "cls_id": "homologset.agr.MGI:1933623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61466-1", "uniprot_id": "SMRD1_MOUSE", "id": "Q61466-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "aln": "------MAARAGFQS--VAPSGGAGASGGAGVAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP---------------------------------------------------------------------------RPGMLPGSRMTPQGPSMGPPGYGGNPSVR-PGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKK-MADKILPQRIRELVPESQAYMDLLAFERKLD-----QTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGE-GTVASWELRVEGRLLEDAALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHR-TATTQETDGFQVKRPGDVNVRCTVLLMLDYQP--PQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHER---------------------------------------EFVLCDKYLQQIFES-------QRMKFSEIPQRLH-ALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKT-------QMNSFLLSTAS------QQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBS9-1", "uniprot_id": "D3ZBS9_RAT", "id": "D3ZBS9-1", "name": "", "aln": "------MAARAGFQS--VAPSGGAGASGGAGVAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPVSGTGGGARGPGAGPSEGGGLTGVREKWEGLPREGLGPGVEVGETERRKSGGKEVSILTCSQRHCFRVRSECGTRRPGMLPGSRMTPQGPSMGPPGYGGNPSVR-PGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKK-MADKILPQRIRELVPESQAYMDLLAFERKLD-----QTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGE-GTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHR-TATTQETDGFQVKRPGDVNVRCTVLLMLDYQP--PQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHER---------------------------------------EFVICDKYLQQIFES-------QRMKFSEIPQRLH-ALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKT-------QMNSFLLSTAS------QQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GM5-1", "uniprot_id": "SMRD1_HUMAN", "id": "Q96GM5-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "aln": "------MAARAGFQS--VAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP---------------------------------------------------------------------------RPGMLPGSRMTPQGPSMGPPGYGGNPSVR-PGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKK-MADKILPQRIRELVPESQAYMDLLAFERKLD-----QTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGE-GTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHR-TATTQETDGFQVKRPGDVNVRCTVLLMLDYQP--PQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHER---------------------------------------EFVICDKYLQQIFES-------QRMKFSEIPQRLH-ALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKT-------QMNSFLLSTAS------QQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYG2-1", "uniprot_id": "BAP60_DROME", "id": "Q9VYG2-1", "name": "Brahma-associated protein of 60 kDa", "aln": "-MSQRFAPGQAPVQSRYQPPPPAPGMRPYPPPGASFPPRGFPLHPNTTQPVPGTANVAG-VPG-------------------------------------------------------------------------------VPGVPGVPGPSLLQRAAQQPGFQS--SLRGTGAGGGGVGSGGGSKRSNESRSLGGGGSKSDFATAKKKKKLAEKILPQKVRDLVPESQAYMDLLTFERKLD-----ATIMRKRLDIQEALKRPMKQKRKLRIFISNTFYPSKEPTNDGEEGAVASWELRVEGRLLEDGKGDPN--TKIKRKFSSFFKSLVIELDKELYGPDNHLVEWHR-THTTQETDGFQVKRPGDRNVRCTILLLLDYQP--LQFKLDPRLARLLGVHTQTRPVIISALWQYIKTHKLQDAHER---------------------------------------EYINCDKYLEQIFSC-------QRMKFAEIPQRLN-PLLHPPDPIVINHFIESG-AENKQTACYDIDVEVDDTLKN-------QMNSFLMSTAS------QQEIQGLDTKIHETVDTINQMKTNREFFLSFAKDPQMFIHRWIISETRDLKLMTDVAGNPEEERRAEFYYQPWTHEAVSRYFFTKVNQKRAELEQALGIRNG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53628-1", "uniprot_id": "SNF12_YEAST", "id": "P53628-1", "name": "Transcription regulatory protein SNF12", "aln": "MSKVMKPSNGKGSRKSSKAATPDTKNFFHAKKKDPVNQDKANNASQITPTVPHSHPSDMVIPDHLAEL--------------------------------------------------------------------------IPELYSFQQLVDSEKRLDHFIHLRNLHMK-RMVAQWERSKLSQEFLYPHLNFPNVKFLRIFISNVSENQ--PWQMDTNNEADLMALENATWTMRIEGRLLDNVQANDPAREKFSSFIESIVVDFKNKENDNVPSTKFNAAPEENATEGP----SDKKLNLNLPLQFSLPNGDNSTTTNTDQNNATMGEETAKKDMSSTTPKLESVKWQYDPNNPVDFDGLDIKRVGSENVECTISILRKSSPEEPFMSYSPQLTAIIGLKSGTSHDAIFSIYKYIHLNELLTNDESAFE----------NLMGNRNNHNSNTSTSKMLDAASSQVSIVKLDTQLITLLPSSLKESSPDTMKLTDLLSLINSTHLLPLQPIEIDYTVRVDKASTYGELVLDIEVPDVNALKFNNTQRESQIGAAELNENARELEQIKPKIALQDKEITSVLSNLHESNKRYRFFKKISEDPVKALNECIASTSNALKVLSGDEGYNEDMVRRANFYK------------ENEAMLRENIEVILSNGRM", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25632-1", "uniprot_id": "RSC6_YEAST", "id": "P25632-1", "name": "Chromatin structure-remodeling complex protein RSC6", "aln": "-------------------------------------------MVTQTNPVPVTYPTDAYIPTYLPDD-------------------------------------------------------------------------KVSNLADLKKLIEMDSRLDLYLTRRRLDTS------INLPTNTKTKDHP----PNKEMLRIYVYNTTESS------PRSDSGTPADSGKTTWTLRIEGKLLHES---ANGKHPFSEFLEGVAVDFKRLKPLGMGKKRKRDSS----------------LSLPLNLQQPEYNDQDSTMGDNDN-----GEDEDSAEAESREEIVDALEWNYDENNVVEFDGIDIKRQGKDNLRCSITIQLRGVDG-GKVQYSPNLATLIGMQTGSVNDAVYSIYKYILINNLFVTEQTEAQDGSNDAEDSSNENNNKNGAGDDDGVEGSTPKDKPELGEVKLDSLLQKVLDTN-----AAHLPLMNVVQTVN-KLVSPLPPIILDYTIDLSKDTTYGATTLDVDVSHILHQPQ-------PQPNLQKEEET------DAEDTAKLREITKLALQLNSSAQKYQFFHELSLHPRETLTHYLWSSKQNELVLQGDQYFNEDAARTSDIYSN----------NNNDRSLMGNISLLYSQGRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* :* . : : ...:.. . :: : : *. . .: *.: :*. . : .. .. * : * . . : . . : . . ::*: . : **:::** *. *:.*:: : .. .*.*: ::*::: : : ::::** ::* .: : *. * :: : : :: . :: : * ** ::: : . *::* . : . : :* . ::. . .*: .:: .* : : * . : . *: * :. : ::. . . ", "identical_positions": 34, "similar_positions": 123, "identity": "5.08%" }, { "cls_id": "homologset.agr.MGI:1933735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GZV4-1", "uniprot_id": "IF5A2_HUMAN", "id": "Q9GZV4-1", "name": "Eukaryotic translation initiation factor 5A-2", "aln": "MAD-EIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDG-YLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V7J7-1", "uniprot_id": "G3V7J7_RAT", "id": "G3V7J7-1", "name": "Eukaryotic translation initiation factor 5A", "aln": "MAD-EIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDG-YLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGY2-1", "uniprot_id": "IF5A2_MOUSE", "id": "Q8BGY2-1", "name": "Eukaryotic translation initiation factor 5A-2", "aln": "MAD-EIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDG-YLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NX89-1", "uniprot_id": "IF5A1_DANRE", "id": "Q6NX89-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MADPDLDFASGDAGASATYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTNKKYEDICPSTHNMDVPNIKRNDYQLVDISEG-FLSLMMDNGDVREDLRVPDGDLGKEIENKFAAGEEMLVTVLSAMGEESAVALKPMTK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GU68-1", "uniprot_id": "IF5A_DROME", "id": "Q9GU68-1", "name": "Eukaryotic translation initiation factor 5A", "aln": "MAELDDQFETTDSGASTTYPMQCSALRKNGFVMLKSRPCKIVEMSTSKTGKHGHAKVHMVGIDIFSNKKYEDICPSTHNMDVPNVKREDLQLIAISDDSFLTLMTESGDLREDLKVPEGELGEQLRLDFDSGKDLLCTVLKACGEECVIAIKTNTALDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23301-1", "uniprot_id": "IF5A1_YEAST", "id": "P23301-1", "name": "Eukaryotic translation initiation factor 5A-1", "aln": "MSDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDG-FLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19211-1", "uniprot_id": "IF5A2_YEAST", "id": "P19211-1", "name": "Eukaryotic translation initiation factor 5A-2", "aln": "MSDEEHTFENADAGASATYPMQCSALRKNGFVVIKGRPCKIVDMSTSKTGKHGHAKVHLVTLDIFTGKKLEDLSPSTHNLEVPFVKRSEYQLLDIDDG-YLSLMTMDGETKDDVKAPEGELGDSMQAAFDEGKDLMVTIISAMGEEAAISFKEAPRSD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : * . *:*:*:***************::*.******:***************:* :***:.** **:.*****::** :**.: **: *.:. :*:*: *: ::*:: *:*:**..:. : *::: ::: * .** .:::* ", "identical_positions": 75, "similar_positions": 52, "identity": "47.17%" }, { "cls_id": "homologset.agr.MGI:1933736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UHD1-1", "uniprot_id": "AGRB1_MOUSE", "id": "Q3UHD1-1", "name": "Adhesion G protein-coupled receptor B1", "aln": "MRGQAAAPGPIWILAPLLLLLLLLGRWARAASGADIGPGTEQCTTLVQGKFFGYFSAAAVFPANASRCSWTLRNPDPRRYTLYMKVAKAPAPCSGPGRVRTYQFDSFLESTRTYLGVESFDEVLRLCDSSAPLAFLQASKQFLQMQRQQPPQDGDLGPQGEFPSSSDDFSVEYLVVGNRNPSHAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGDVGDPASSPLVPRGDVCLRDGVAGGPENCLTSLTQDRGGHGSAGGWKLWSLWGECTRDCGGGLQTRTRTCLPTLGVEGGGCEGVLEEGRLCNRKACG-------------------------PTGRSSSRSQSLRSTDARRREEFGDELQQFGFPSPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCP-----VHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSTCSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGGGSQRRERVCSGPFFGGAACQGPQDEYRQCGAQRCPEPHEICDEDNFGAVVWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAFWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLLEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQIISNLLAEENRDKWEEAQLMGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLAEADDSSVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLLTPLEIEFAHMYNGTTNQTCILWDETDGPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADAT----MDKVTVPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIG-------QTQTRNKVVCTLVAAFLHFFFLSSFCWVLTE---AWQSYMAVTGRLRSRLVRKRFLCLGWGLPALVVAISVGFTKAKG---YSTMNYCWLSLEG--GLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAG---------------------------------ASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVVDRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTFKRPSLPEEEKMKLA---KGPPPTFNSLPANVSKLHLHGSPRYPGGPLPDFPN-HSLTLKKDKAP--KSSFIGDGDIFKKLD---SELSRAQEKALDTSYVILPTATATLRPKP--KEEP--KYSINIDQMPQTRLIHLS----MAPDASFPTRSPPAREPPGGAPPEVPPVQPPPPPPPPPPPPQQPIPPPPTLEPAPPSLGDTGEPAAHPGPSSGAGAKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNRKLQHAAEKEKEVPGADSKP-----------------EKQQTPNKRAWESLRKPHGTPAWVKKELEPLPPSPLELRSVEWEKAGATIPLVGQDIIDLQTEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HL12-1", "uniprot_id": "AGRB1_RAT", "id": "C0HL12-1", "name": "Adhesion G protein-coupled receptor B1", "aln": "MRGQAAAPGPIWILAPLLLLLLLLGRWARAASGADIGPGTEQCTTLVQGKFFGYFSAAAVFPANASRCSWTLRNPDPRRYTLYMKVAKAPAPCSGPGRVRTYQFDSFLESTRTYLGVESFDEVLRLCDPSAPLAFLQASKQFLQMQRQQPPQDGDLGPQG----SGDDFSVEYLVVGNRNPSHAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGDTASSPLVPRGDVCLRDGVAGGPENCLTSLTQDRGGHGSAGGWKLWSLWGECTRDCGGGLQTRTRTCSPTLGVEGRGCEGVLEEGRLCNRKACG-------------------------PTGRTSSRSQSLRSTDARRREEFGDELQQFGFPSPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCP-----VHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSTCSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGGGSQRRERVCSGPFFGGAACQGPQDEYRQCGAQRCPEPHEICDEDNFGAVVWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAFWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLLEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQIISNLLAEENRDKWEEAQLMGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLAEADDSSVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLLTPLEIEFAHMYNGTTNQTCILWDETDGPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADAT----MDKVTVPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIG-------QTQTRNKVVCTLVAAFLHFFFLSSFCWVLTE---AWQSYMAVTGRLRSRLVRKRFLCLGWGLPALVVAISVGFTKAKG---YSTMNYCWLSLEG--GLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAG---------------------------------ASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVVDRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTFKRPSLPEEEKMKLA---KGPPPTFNSLPANVSKLHLHGSPRYPGGPLPDFPN-HSLTLKKDKAP--KSSFIGDGDIFKKLD---SELSRAQEKALDTSYVILPTATATLRPKP--KEEP--KYSINIDQMPQTRLIHLS----MAPDASFPTRSPPAREPPGGAPPEVPPVQPPPPPPPPPPP-QQPIPPPPSLEPAPPSLGDTGEPSAHPGPSSGAGTKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNRKLQHAAEKEKEVPGVDNKP-----------------EKQQTPNKRAWESLRKPHGTPAWVKKELEPLPPSPLELRSVEWEKAGATIPLVGQDIIDLQTEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14514-1", "uniprot_id": "AGRB1_HUMAN", "id": "O14514-1", "name": "Adhesion G protein-coupled receptor B1", "aln": "MRGQAAAPGPVWILAPLLLLLLLLGRRARAAAGADAGPGPEPCATLVQGKFFGYFSAAAVFPANASRCSWTLRNPDPRRYTLYMKVAKAPVPCSGPGRVRTYQFDSFLESTRTYLGVESFDEVLRLCDPSAPLAFLQASKQFLQMRRQQPPQHDGLRPRAGPPGPTDDFSVEYLVVGNRNPSRAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCLRDAVAGGPENCLTSLTQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACG-------------------------PAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCP-----VHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADAN----MEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIG-------QTQTRNKVVCTLVAAFLHFFFLSSFCWVLTE---AWQSYMAVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKG---YSTMNYCWLSLEG--GLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAG---------------------------------ASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVVDRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTLKRPSLPEEEKLKLAHA-KGPPTNFNSLPANVSKLHLHGSPRYPGGPLPDFPN-HSLTLKRDKAP--KSSFVGDGDIFKKLD---SELSRAQEKALDTSYVILPTATATLRPKP--KEEP--KYSIHIDQMPQTRLIHLS----TAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAHPGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNRKLQHAAEKDKEVLGPDSKP-----------------EKQQTPNKRPWESLRKAHGTPTWVKKELEPLQPSPLELRSVEWERSGATIPLVGQDIIDLQTEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8PX08-1", "uniprot_id": "A0A2R8PX08_DANRE", "id": "A0A2R8PX08-1", "name": "", "aln": "MISKFLGNCSSLILLFPLLQLLRMDMLNAAPS----GPETDSCSTLVQSRFFGFFLSSSAFPS--MPCTWTLQNPDPRRYTIFIKVTKPTRDCIAR-QHRTFQFDSFLETTRTFLGMESFDEVVKLCDASTHVAFLEAGKQFLQIRKGLPRAGAGSRNGD------GEFKVEYLVVGKRNPSMAACQMLCQWLEDCLTYSSSTRPCGIMQTPCQCWD-------QPPLDKESNGCYRDGVF--LENCIPVVKEGASETDNSGGWSGWGNWAECSSECGGGVQKRTRNCQSPP-DEAYLCEGVLEEGRPCNAQPCIGYRQYSSKGQGLSPVKYKGMQEAMLGKGRLGSRSQSLRSVDSRKREDS-DKTRSGQQSSQTVDSPSGEEWSAWSVCSATCGEGWQSRTRFCVSVSYSTQCSGPLREQRPCNNTAVCPAALITEHGAWGEWTPWSLCSSTCGRGYRERNRSCKPPQFGGNPCDGPEKQTKFCNIAVCP---VDGVWNEWSGWSSCSSTCSNGTMQRIRECNGPSYGGLECQGEWHETRDCFLRECPVDGQWQLWSTWSGCTKTCGGGSQQRQRLCYGPFFGGEACPGDREEVRRCNEKRCPEPHEICDEENFSNVVWKKTPAGDTAAVRCPPNAVGLILRRCSLDNEGIAYWENPTYMKCVSNDYRSIQTLTRDHLSKAQRGLVGDGVSEVMTKLRVTSSDGTSYSGDLLAIIDVLKNMTEIFRRSYYSPSNADMRNFVQSVSNLLMEENRDRWEEAQLLGPNVKELFRLVEDFVDVISLRMKDFQDTYEVTDNLVLSIHKRPVAGNADITFPMKGWRGMVDWARSSEDKVRVAKNILLTGKPEEDDASAFVTGIVLYRNLGSILSLQRNSTVLNSKVISVTIKPTPSSLSSPLEIEFSHLYNGTTNQTCISWDENDSSS-----LLGSWSARGCRAVPVDSSTTKCLCDRLSTFAILARLNPDVN----MDKTQLPSVTLIVGCGVSSLTLLLLIIIYVSVWRYIRSERSVILINFCLSIISSNALILIG-------QTQTRNKVVCTLVAAFLHFFFLSSFCWVLTE---AWQSYMAVTGRLRNRIIRKRFLCLGWGLPALVVAISVGFTKAKG---YGTVNYCWLSLEG--GLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDMKLKERAGQMTVPLYNMTLKCAKCGVISSPDVSTTATSNAMASLWSSCVVLPLLALTWMSAVLAITDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQEAVKCRVVDRQEDGNGDSGGSFQNGHAQLMTDFEKDVDIACR---------------SGTLKRPSQQGEEKVPSQQITVQKGSNFNTLPASMAKVHLQNVANYASHTLTMRRDKGAIAGVSTELPGAKSIYICDGELFKQLDGAPGDIPEGGGGGAGQGYVLLPNNNNTLRPTKGGKEDPAAKYNISIEQLPQTRLIHLANPVGTDPVAGFGLKSLPTDRVSVSCSERESPVQT-----------VQNISSESQMTNTCE-QGDSG---------NSGMSKSETVSTLSMSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNRKLQHAE-KDRDSPPVDCKPGKRWSISSGGSDKTNLSDKQQTPSKRAWEGIRKTHSPPSWVRKELEPLQASPLEMQAVEWEKASATIPLVGQEIMDLQTEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA10-1", "uniprot_id": "Q9VA10_DROME", "id": "Q9VA10-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLFLWWIAGYIILVSGGTNPPLYALDQPNVARCLDYCHLKNLR----------------------FLLCVDADG-------------QLSHNPYKD-------CNRGFCKAEDFELEYETDEGKEKRINRVEKTRVGQKANLRDLCLN---------ERGIPIRRRCQIRNGNRVWQSLD--HVTCRSAPELSSSIN------LLAVKSPPDMISQLSNLLTQTQEKLAAADVFSISEIFDS------LVKKPERNAAVVGDLMKICQKVMSTDNETLRVSADANATNALLSNFEDYLDELSP--------TILKLNTTIFANSTEFTFHPLFDMGVIVLKTSELRVFFVDPEVRNVSGIVNFSGGNMS----------------HFEMLHLSDNEEDIR--AMKNLESAVFIPEKLWTQLKRK---GASYLVFKVY-----------TRDSLFVETEEEIKRRPTSNVISITIPGLNDTKLPGKLPFFLRN----------------------------AKANETQFEGGCGYWNYETWLS------DGISTSGGGSLEASSHPVILCHADHLTQFTFLLGVSKMQAGLDTNEDDHSLDVITNVGLTLSLLGLLMIFITAAVFKSFRTLASTKILLNLCAALGLQLLFFLILSQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWMFIIGFLQYQRYVRVIGVNHPRHYILMSAVAAWTLPLIPTLLVVFLEPGSYRPNNSSMDYPILCYPSGYGLSLGVILPIGLITVANAILVGYISWSVYTALFKRDLIFKQLGL--------------------------------------FVLLFFLLGITWIFGLCTYFDFG-RIFAYLFCLTATLQGFVLFLYFIVFNKENQRAWLGLCCNSSKKRNQQTIQMPTDSILQGLSHSSTNSTSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .* . . :.:. . ::* . : :. : ** .: * *:. ** .. ** ..* .: :: .. . .: : : .. . . * : :.* : . : * : . ** ...: . : * . : : . .::. : *. .: *: * . ..:: .: :: :: : . : . : . : .::* : . :: :.*.:: . * :.*: *. :* : .* :: .:*: .. : *:::* :: *: **::..: :.::* .::: * : : * : ..* : * .. . . : * : * : *.: : ** :: : : * *: * * : * . . * .*:*: *::* :. :. .* ** :* * **::.* . . : : **:*:* :: . ::** * : :. ****.*.:::::* *.*:: :* *: * * : * .* ** : . : * : .. .:::* *. . ** ..: * . :.:.* :: : .: : * :*: . ::: **.:**: .: : * :* **.: :*:***:.: . ::.:* * * : .:. * :: :. * ::. ..: ", "identical_positions": 111, "similar_positions": 263, "identity": "6.54%" }, { "cls_id": "homologset.agr.MGI:1933744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPQ5-1", "uniprot_id": "CENPQ_MOUSE", "id": "Q9CPQ5-1", "name": "Centromere protein Q", "aln": "MSGKARASRKKPQQVKRSLKQRANK---EADLPENEVGNTAKRNRSHAKHLSSKVTGQATYVHLKRVKISSSKRTTWQPLPKDTEEYLQSMMESVILGILFN-IKRKEEIQCHLNQLKKRLLQQCATLKVPPRKLNYLKDVSKMLKMEKAQERANEESLASLQEEIDKIVETTESMTESIQSLKNKIQILTSEVEEEEQEVKQVFHIDSNKVLALPELSQKSLKAPILQEEILALIPNQNALLKDLDVLHDSAPVKNVSAFIEEAYKKLDS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H02-1", "uniprot_id": "CENPQ_RAT", "id": "Q66H02-1", "name": "Centromere protein Q", "aln": "MSGKANTSKKKSQRVKRNVKQRADKEDEELDSPENKVGNRAKRNRSHAGHLSSKE--QTKCVHLKRVKISSNKRTAWQPLPKNTEEYLQSMMDSAILGILNKNIKRKEQIQYHLDQLKKRFLQQCATLKVPPGKLNYLRDMSKLLKVEREQERANEESLASLQEEIDKIVETTESMTENIESLKTKIEILTNEVEKEEEEMKEVFHIDSNKVLALPELSQKSLKAPILQKEILTLIPNQNALLKDLDVLQNSAPGKNMAAFIQEAYMKLNGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L2Z9-1", "uniprot_id": "CENPQ_HUMAN", "id": "Q7L2Z9-1", "name": "Centromere protein Q", "aln": "MSGKANASKKNAQQLKRNPKRKKDN--EEVVLSENKVRNTVKKNKNHLKDLSSEG--QTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.:*:*:.*::**. *:: :: * .**:* * .*:*:.* .***: *:. .:**: * ::.**.:****.*.*.::**:**:*.*: ** : **.**:** **: ****:**** ****** *:: * ::*.:*::*: :::****.** *******:***** ** .*:***.**:**:.***:**:.:*::.:*:*. **:*******:**** **:***:*************:*::*: *.:::**:*** **:. ", "identical_positions": 146, "similar_positions": 89, "identity": "53.68%" }, { "cls_id": "homologset.agr.MGI:1933754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96PU5-1", "uniprot_id": "NED4L_HUMAN", "id": "Q96PU5-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "---------------------------------------MATGLG-EPVYGLSE------DEGESR-ILR------VKVVSGID------------LAKKDIFGASDPY---------------------------------------------------------------------------------------------VKLSLYVADENRE----------------------LALVQTKTIKKTLNPKWN-EEFY---------------------------FRVNPSNHR---------------------------LLFEVFDEN----------------------------------------------------RLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPR---SHKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPP-----LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSES--DNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGG-DVPEPWETIS-EEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQ--FSSLIQREPSSRLRSCSVTDAVAEQGHLPPPS--APAGRARSSTVTGGEEPT-PSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLA-EDGASG----------------SATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK--FPVHMRSKTSLNP---NDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT-ELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CFI0-1", "uniprot_id": "NED4L_MOUSE", "id": "Q8CFI0-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "--------------MSLCEAPVHVGDKELK---YFQIPQMLSQLS-LLASHHSRGLEFSGGQGESR-ILR------VKVVSGID------------LAKKDIFGASDPY---------------------------------------------------------------------------------------------VKLSLYVADENRE----------------------LALVQTKTIKKTLNPKWN-EEFY---------------------------FRVNPSNHR---------------------------LLFEVFDEN----------------------------------------------------RLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPR---SHKSRVKGFLRLKMAYMPKNGGQDEENSEQRDDMEHGWEVVDSNDSASQHQEELPPPP-----LPPGWEEKVDNLGRTYYVNHNNRSTQWHRPSLMDVSSES--DNNIRQINQEAAHRRFRSRRHISEDLEPEASEGGGEGPEPWETIS-EEMNMAGDSLSLALPPPPASPVSRTSPQELSEEVSRRLQITPDSNGEQ--FSSLIQREPSSRLRSCSVTDTVAEQAHLPPPS--TPTRRARSSTVTGGEEPT-PSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLA-EDGASG----------------SATNSNNHLVEPQIRRPRSLSSPTVTLSAPLEGAKDSPIRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK--FPVHMRSKASLNP---NDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT-ELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JUY1-1", "uniprot_id": "A0A0G2JUY1_RAT", "id": "A0A0G2JUY1-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "MAHRLRFHFGSGRSNTAPESEILDQEREED---FFMAFQTLPRRSSPHPFTQNAGEDSGLQEGVGA-LKRSSSMFIPQLLAGVDARPTRSSSMKISLQRKAADGATDSCGPQEGPDDRPPSAQGDLGDQAAATRVSAQIGSSEPSPVDTPGSSPPRAAWDPGTLVNGTCDHRGPSPRLAEDTEEATPGLRIQHRASSADVRQVRLLPFGPDGQAEPRRWSLQHVPDASGSSGKRCFVFQLQQPHQGTVGLGSDFN-FGFTGTKGDRLVRYPRIRLERSTSYPTQPRAGRVSPTEDRGTPEASPRRMVPEIRRTNSERTPQSPGCMFKIRQDQNAGQQHFRILVTRGPEEAPQNQEETPKSPGHPGTG-----------------VPTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPR---SHKSRVKGFLRLKMAYMPKNGGQDEENSEQRDDMEHGWEVVDSNDSASQHQEELPPPP-----LPPGWEEKVDNLGRTYYVNHNNRSTQWHRPSLMDVSSES--DNNIRQINQEAAHRRFRSRRHISEDLEPEASEGGGEGPEPWETIS-EEVNMAGDSLSLALPPPPASPVSRTSPQELSEELSRRLQITPDSNGEQ--FSALIQREPSSRLRSCSVTDTVAEQAHLPPP-----------------------SVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLA-EDGASG----------------SATNSNNHLVEPQIRRPRSLSSPTVTLSAPLEGAKDSPIRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK--FPVHMRSKASLNP---NDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT-ELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PD40-1", "uniprot_id": "A0A8M9PD40_DANRE", "id": "A0A8M9PD40-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "MSHRLRLYFGSGRSNTAPELEELNGTVEEEGDISYNSTGAMVVHAQPRNGGHAESPEPGTVVGSDASLKRSSSMFIPQLQGQAESRTTKSTSVQISLQRTTAPHEDALPFDPPPAYPQDPAPPYTEPGESLPLPPPPTYYKSCQNVEQTQKDTEPKRQ----VFCVRPCDGQNGYTHGNPQGITIGGVCIRRRSADGSDVQQFRIMPYSEDGHNG-HNWSVQQCSDRGPGAQRLIFQLQKDQGRQPSSTSQPDVSDLGITGSKGSRLVRYPRIRLERSTSQP-----LQPRGAPSRLGSMPNLHAPISEMETESDFIENGAQGCTFKIRKEQNSQQPKFKIYFSQGGEHSPILERNISIGKAPTCSNPQAHIGLDRPKNGHFNNGQTRDDFLGQVDVPLTHLPTEDPAMERPYTFKDFLLRPR---SHKSRVKGYLRLKMAYLPKNGGHEEESGEMREEAEG-WEVTDSTDPGSQRPQQLLPP------LPPGWEEKVDNLGRTYYVNHNNRTTQWKRPSSVDVVSETENDNQLRQINQEA-HRVFRSRRHISEDLENEQLDIR-DIDDSWEPISEEDPTLLTDGLNHSLSGPSSLAMPLSSTPDFSDEISLRLSLAPDTNGEIPGPSSAVQSHLSSRLRSSSMTDGVSDQAQPPTPTQSSQTRRTRAQTVTGVEDTMSPSASYALTTPGLPPGWEERKDPKGRTYYVNHNNRSTTWTRPILQQHTEDGASTSVAAVGGATAATPPASTPSTSSGHLSEPQVRRPRSLSSPTVTLSSPLEGANNVPIRRAVKDTFSNPQSPQPSPYSSPKTQHKANQSFLPPGWEMRIAPNGRPFFIDHNSRTTTWEDPRLK--YPVHMRTKASLDP---GDLGPLPPGWEERVHADGRTFYIDHNNKKTQWEDPRLQSPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSLKRPDSLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT-ELDLRFCIDEDNFGQTYQVDLKPSGSDMVVTNDNKKEYIDLVIQWRFVNRVQKQMNAFLEGFTELIPIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGTPDKLPRAHTCFNRLDLPMYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVI3-1", "uniprot_id": "NEDD4_DROME", "id": "Q9VVI3-1", "name": "E3 ubiquitin-protein ligase Nedd-4", "aln": "MSARSSGLVAAAALPVPSSSSSVAGGDVPRPPPRRRAASVAGQQQTRQEFGNGYTPRRSLAAVNDS---GDSCHLRIVVLTGQS------------LAKKDIFGASDPY---------------------------------------------------------------------------------------------VRIDLNTINGDIN----------------------IDSVLTKTKKKTLNPTWN-EEFI---------------------------FRVKPSEHK---------------------------LVFQVFDEN----------------------------------------------------RLTRDDFLGMVELTLVNLPTEQ--EGRTIGEQSYTLRPRRSVGAKSRIKGTLRIYHAFIRETREQSEPSS---GNSDGEWEHVEATNAGETSAQPHPFPTGGHDALPAGWEERQDANGRTYYVNHTARTTQWDRPTVLNSHSSQ--------STDDQLASDFQRRFHISVDDTESGRSADSISHNSIEDNN-NAAGLAYTPKTAATS--SAPPNTPTNNNGILAQIAMQYRAEEDQDPTVDHTSFVYNSLRHPVAHRQPEISATSLQNDLRPVR--------EAPGVPDIAITNPFTRRAAGNMAGGAGWQQERRRQQMQLHIQQHQQRQQQQQQNRILLDVDHRQQE-------------------PQHRGQRHQQQHRPSNEDTDHTDSHNPSDISAPSTRRNSEEDNAAVPPMEQN---------TGGEEEPLPPRWSMQVAPNGRTFFIDHASRRTTWIDPRNG--RASPMPNQTRRVE---DDLGPLPEGWEERVHTDGRVFYIDHNTRTTQWEDPRLSNPNIAGQAVPYSRDYKQKYEYFKSHIRKPTNVPNKFEIRIRRTSILEDSYRIISSVTKTDLLKTKLWVEFEGETGLDYGGLAREWFYLLSKEMFNPYYGLFEYSAMDNYTLQINNGSGLCNEEHLSYFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQKPIDLKDMESVDTEYYNSLMWIKENDPR-ILELTFCLDEDVFGQKSQHELKPGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELLMCGIQNIDVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQMFTIEKWGTPNNFPRAHTCFNRLDLPPYEGYLQLKDKLIKAIEGSQGFAGVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39940-1", "uniprot_id": "RSP5_YEAST", "id": "P39940-1", "name": "E3 ubiquitin-protein ligase RSP5", "aln": "------------------------------------------------------------MPSSIS----------VKLVAAES------------LYKRDVFRSPDPF------------------------------------------------------------------------------------------------AVLTIDGYQT-------------------------KSTSAAKKTLNPYWN--------------------------------------------------------------------ETFKFDDIN----------------------------------------------------------------------------ENSILTIQVFDQKK-----FKKKDQGFLGVVNVRVGDVLGHLDEDT--------------ATSSGRP---------------------REETITRDLKKSNDGMAVSGRLIVVLSKLPSS-------------------------------------------------------SPHSQAPSGHTASSSTNTSSTTRTNGHSTSSTRNHSTSHPSRGTAQAVESTLQSGTTAATNTATTSHRSTNSTSS------------------ATRQYSSFEDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQTEAERGNQ-------------------LNANTELERRQHRGRTLPGGSSDNSSVTVQVGGGSNIPPVNGAAAAAFAATGG--------TTSGLGELPSGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPTNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPS-SLDQNVPQYKRDFRRKVIYFRSQP-ALRILPGQCHIKVRRKNIFEDAYQEIMRQT-PEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAYDNYTIQINPNSGIN-PEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLENSIDGVLDLTFSADDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYR-GYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIGFGQE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : : . . . *:. . : : : : *.: :* * : . : . : : . :.... : : * .: :.. :. .. : . .: . . :. : . . : : . . .: : . . :.* : : :*: * : : . . . . : :* . . . :. : . **. *. :.:*:**.:*:** :: *** *** .:: .:***** *** *: .*.:::***.: * *:**** . : . *.*::::* **:.: :*.: .::::*..*:*::*: * . .: ** :* ::*:.* ******::**:*:***:*****:* ****** ****:*** .**: :**.**.****:.*:.*:* ::**.**: .:***** * : *:***.**:* **** *: **. *:* *. *:: **: :***.* :: **: ** **:.* :**:* **::*:.:*::** .::* :*:.:***.*****: *: ::*::**:::: *: .* .. :*****:.* . * * *****.*****:*:*** :* **:**: ****: * :::*::******:*** * : .:::** *:* : ** ", "identical_positions": 219, "similar_positions": 235, "identity": "16.82%" }, { "cls_id": "homologset.agr.MGI:1933765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58544-1", "uniprot_id": "BTBD1_MOUSE", "id": "P58544-1", "name": "BTB/POZ domain-containing protein 1", "aln": "MASLGSAAAGEPATGAEAEPGPPAPPPPPPPPPAPSPSALGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTVDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAIVRWAEAECQRQQLAVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRISVVGFGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCYTACATLKGPDSHYGTKGLKKVVHETPAASKTVFLFFSSPGNNNGTSIEDGQIPEIIFYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0C5-1", "uniprot_id": "BTBD1_HUMAN", "id": "Q9H0C5-1", "name": "BTB/POZ domain-containing protein 1", "aln": "MASLGPAAAGEQASGAEAEPGPAGPPPPP------SPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRISIVGFGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCYTACATLKGPDSHYGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSIEDGQIPEIIFYT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.***** *:********..***** ***:******************************************************************************************************************************************************************************:***********************************:*************.******************************************************************************************************:***********************************************************************************************:*************************", "identical_positions": 471, "similar_positions": 10, "identity": "96.52%" }, { "cls_id": "homologset.agr.MGI:1933786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K5E4-1", "uniprot_id": "A0A0G2K5E4_RAT", "id": "A0A0G2K5E4-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAARCSPRWFRVAVGTPRLPAAAGRGVQQPQGGVVAASLCRKLCVSAFGLSMGAHGPRALLTLRPGVRLTGTKSFPFVCTASFHTSASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGASS--SGQGY------WRGGP---SVDPEELFRKIFG--EFSSSPFGDFQN----VFDQPQEYIMELTFNQAAKG-VNKEFTVNIMDTCERCDGKGNEPGTKVQHCHYCSGSGMETINTGPFVMRSTCRRCGGRGSIITNP--CVVCRGAGQAK-QKKRVTVPVPAGVEDGQTVRMP-------------------VGKREIFVTFRVQKSPVFRRD-GADIHSDLFISIAQAILGGTAKAQGLY-ETINVTIPAGIQTDQKIRLTGKGIPRINSYGYGDHYIHIKIRVP--KRLSSRQQNLILSYAEDETDVEGTVNGVTHTSTG------GRTMDSSTGSKDRR---EAGE-------------------DNE--------------------GFLSKLKKIFTS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M87-1", "uniprot_id": "DNJA3_MOUSE", "id": "Q99M87-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAAWCSPRWLRVAVGTPRLPAAAGRGVQQPQGGVVATSLCRKLCVSAFGLSMGAHGPRALLTLRPGVRLTGTKSFPFVCTTSFHTSASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGTSS--SGQGY------WRGGP---SVDPEELFRKIFG--EFSSSPFGDFQN----VFDQPQEYIMELTFNQAAKG-VNKEFTVNIMDTCERCDGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIITNP--CVVCRGAGQAK-QKKRVTIPVPAGVEDGQTVRMP-------------------VGKREIFVTFRVQKSPVFRRD-GADIHSDLFISIAQAILGGTAKAQGLY-ETINVTIPAGIQTDQKIRLTGKGIPRINSYGYGDHYIHIKIRVP--KRLSSRQQNLILSYAEDETDVEGTVNGVTHTSTG------GRTMDSSAGSKDRR---EAGE-------------------DNE--------------------GFLSKLKKIFTS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EY1-1", "uniprot_id": "DNJA3_HUMAN", "id": "Q96EY1-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAARCSTRWLLVVVGTPRLPAISGRGARPPREGVVGAWLSRKLSVPAFASSLTSCGPRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGASG--SQHSY------WKGGP---TVDPEELFRKIFG--EFSSSSFGDFQT----VFDQPQEYFMELTFNQAAKG-VNKEFTVNIMDTCERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIIISP--CVVCRGAGQAK-QKKRVMIPVPAGVEDGQTVRMP-------------------VGKREIFITFRVQKSPVFRRD-GADIHSDLFISIAQALLGGTARAQGLY-ETINVTIPPGTQTDQKIRMGGKGIPRINSYGYGDHYIHIKIRVP--KRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSG------GSTMDSSAGSKARR---EAGE-------------------DEE--------------------GFLSKLKKMFTS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27237-1", "uniprot_id": "DJTID_DROME", "id": "Q27237-1", "name": "DnaJ homolog l(2)tid, mitochondrial", "aln": "MMISCKK--LFVFR---QLPAVR-----------------RCLAAAAFST------PRATSYRILSSAGSGSTRADAPQVRRLHTTRDLLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRREYDTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQS---WQFRS---SIDPEELFRKIFGEGNFRTNSFDDFADSK-FGFGQAQEMVMDLTFAQAARG-VNKDVNVNVVDQCPKCAGTKCEPGTKPGRCQYCNGTGFETVSTGPFVMRSTCRYCQGTRQHIKYP--CSECEGKGRTV-QRRKVTVPVPAGIENGQTVRMQ-------------------VGSKELFVTFRVERSDYFRRE-GADVHTDAAISLAQAVLGGTVRVQGVY-EDQWINVEPGTSSHHKIMLRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIEAYAELEEDTPGQIHGIANRKDGSKQATAGASEEPGAGAAAKASAAAAGSGASKPGPGAEKSEGKDQWTDNEKTKAKEGGGSGSGQGDGGGGGFISKIKSMFN------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35191-1", "uniprot_id": "MDJ1_YEAST", "id": "P35191-1", "name": "DnaJ homolog 1, mitochondrial", "aln": "--MAFQQGVLSRCSGVFRHHVGHSR------------------------------HINNILYRHAIAFASIAPRIPKSSFHTSAIRNNEAFKDPYDTLGLKKSATGAEIKKAYYKLAKKYHPDINKE-PDAEKKFHDLQNAYEILSDETKRQQYDQFGPAAFGGGGAAGGAGGGSGSPFGSQFHDFSGFTSAGGSPFGGINFEDLFGAAFGGGGRGSGGASRSSSMFRQYRGDPIEIVHKVSFKDAVFGSKNVQLRFSALDPCSTCSGTGMKPNTHKVSCSTCHGTGTTVHIRGGFQMMSTCPTCNGEGTMKRPQDNCTKCHGEGVQVNRAKTITVDLPHGLQDGDVVRIPGQGSYPDIAVEADLKDSVKLSRGDILVRIRVDKDPNFSIKNKYDIWYDKEIPITTAALGGTVTIPTVEGQKIRIKVAPGTQYNQVISIPNMGVPKTSTIR-GDMKVQYKIVVK--KPQSLAEKCLWEALADVTNDDMAKKTMQPGTAAG------TAINEEILKKQKQEEEKHAKK-------------------DDD--------------------NTLKRLENFITNTFRKIKGDKKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : : .* * **: :.*. :******:******** **: *.* .** :: :***:**** **::** :* .* * .. . . . . :: *:** ** :. . .:. * . .::* :*. * * :. .. :* * * *. :*.*: * * *:* . * * * *** * * * *.* * : : : : :* *:::*:.**: :. :::: :**::. * . *: * *.:: * ****. : : :.: .* . .: * : . *: : .: ** :: ** * * . * : *: * . . * : : * . *:: . :.:::.::. ", "identical_positions": 102, "similar_positions": 122, "identity": "17.23%" }, { "cls_id": "homologset.agr.MGI:1933820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI59-1", "uniprot_id": "JAM2_MOUSE", "id": "Q9JI59-1", "name": "Junctional adhesion molecule B", "aln": "---MARSPQGLLMLLLLHYLIVALDYHKANGFSASKDHRQEVTVIEFQEAILACKT-PKKTTSSRLEWKKVGQGVSLVYYQQALQGDFKDRAEMIDFNIRIKNVTRSDAGEYRCEVSAPTEQGQNLQEDKVMLEVLVAPAVPACEVPTSVMTGSVVELRCQDKEGNPAPEYIWFKDGTSLLGNPKGGTHN-NSSYTMNTKSGILQFNMISKMDSGEYYCEARNSVGHRR-CPGKRMQVDVLNISG--IIATVVVVAFVISVCGLGTCYAQRKG------YFSKETSFQKGSPASKVTTMSENDFKHTKSFII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57087-1", "uniprot_id": "JAM2_HUMAN", "id": "P57087-1", "name": "Junctional adhesion molecule B", "aln": "---MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQ-QVVTAVEYQEAILACKT-PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRR-CPGKRMQVDDLNISG--IIAAVVVVALVISVCGLGVCYAQRKG------YFSKETSFQKSNSSSKATTMSENDFKHTKSFII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V233-1", "uniprot_id": "B0V233_DANRE", "id": "B0V233-1", "name": "", "aln": "MLLQQPYITKMKTKQLLTSALLLLIYIPSSDPVTVTTSKAKMDVHENTNAVLSCEFRTEKETNPRVEWKKRGKDVSYVYFEGDFTGSYKGRASIDGATLTLRGVTQKDSGVYHCEVTARQDK-IKLGEVSVTLSVLVPPHAPTCEVPEAVMRGFSAELHCKDKLSVPAATYSWYKD-----NKPLNTANPHDVHYTLDTKTGSLKFKSVSKSDEGQYRCEASNGVGAPKSCAGHHMKITEFELNMTMIIAIEVGAFLLLVSCCVSICLCCRRGCCHCCRRQSKEEIKQSKTKTSYNQPTDPRRYKHTQSFVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :: * * : . : . : . * :*:*:*: .:* ...*:**** *:.** **:: : *.:*.**.: . .: ::.**:.*:* *:***:* :: :* * .* *.***.* .*:**** :.: * .**:*:** . **. * *:** :* :: : **::**:* *:*: :** * *:* *** *.** : *.*::*:: :::. *** * . ::: * :. * . *:* *** *. . :* . . . :***:**::", "identical_positions": 97, "similar_positions": 96, "identity": "31.09%" }, { "cls_id": "homologset.agr.MGI:1933825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FQ2-1", "uniprot_id": "JAM3_RAT", "id": "Q68FQ2-1", "name": "Junctional adhesion molecule C", "aln": "MALSRRLRLRLCARLPDFFLLLLFRGCVIE--AVNLKSSNRNPVVHEFESVELSCIITDSQTNDPRIEWKKIQDGQTTYVYFDNKIQGDLAGRTDVFGKTSLRIWNVTRSDSAIYRCEVVALNDRKEVDELTIELIVQVKPVAPVCRVPKAVPVGKAATLQCQESEGYPRPYYSWYRNDVPLPTDSRANPRFQNSSFHVNSETGTLVFSAVHKEDSGQYYCIASNDAGAARCEGQDMEVYDLNIAGIIGGVLVVLIVLAVITMGICCAYRRGCFISSKQDGESYKSPGKHEGVNYIRTSEEGDFRHKSSFVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8B7-1", "uniprot_id": "JAM3_MOUSE", "id": "Q9D8B7-1", "name": "Junctional adhesion molecule C", "aln": "MALSRRLRLRLYARLPDFFLLLLFRGCMIE--AVNLKSSNRNPVVHEFESVELSCIITDSQTSDPRIEWKKIQDGQTTYVYFDNKIQGDLAGRTDVFGKTSLRIWNVTRSDSAIYRCEVVALNDRKEVDEITIELIVQVKPVTPVCRIPAAVPVGKTATLQCQESEGYPRPHYSWYRNDVPLPTDSRANPRFQNSSFHVNSETGTLVFNAVHKDDSGQYYCIASNDAGAARCEGQDMEVYDLNIAGIIGGVLVVLIVLAVITMGICCAYRRGCFISSKQDGESYKSPGKHDGVNYIRTSEEGDFRHKSSFVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BX67-1", "uniprot_id": "JAM3_HUMAN", "id": "Q9BX67-1", "name": "Junctional adhesion molecule C", "aln": "MALRRPPRLRLCARLPDFFLLLLFRGCLIG--AVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQDGESYKNPGKPDGVNYIRTDEEGDFRHKSSFVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KPA0-1", "uniprot_id": "JAM3B_DANRE", "id": "A3KPA0-1", "name": "Junctional adhesion molecule 3B", "aln": "MALTP----------LACVLLLLSMQCYISTLAVLLKSTNSKPWVNEFESIELSCMIESITTTKPRIEWKKIKNGDPSYVYFDNQISGDLERRAKIREPATLVILNATRSDSADYRCEVTAPNDQKSFDEILISLTVRVKPVVPRCSVPKSIPVGKPAELHCLEDEGYPKSQYQWFRNKEEIPLDPKSSPKFFNSTYTLDGEMGTLKFSAVRKEDAGEYYCRAKNEAGISECGPQMMEVYDINIAGIILGVVVVVMVLLCITVGIFCAYKRGYFTSQKQTGNNYKPPAKGDGVDYVRTEDEGDFRHKSSFVI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B6E9-1", "uniprot_id": "A0ACD6B6E9_DANRE", "id": "A0ACD6B6E9-1", "name": "", "aln": "MAFGR----------QTLSLVLFCWLCNSAAFAVILRTTEKSVWANEFESIELTCLIESISTNNPRIEWKKIKNGVPSYVYFQNKISGDLEHRALLREPANLLILNASRSDTAQYRCEVAAIDDQKPFDEILISLAVRVKPVIPRCSVPDAVTVGSSTELRCIENEGFPQSQYQWFKNSEELPEDPKTSSKFYNSSYIMNIETGSLKFRSVKKEDAGEYYCQARNEAGWSKCIRQSMEVYDLDIVGIFLKVLGGVAAFIFVIVGICQIQKSGYCSCKDHRETNYKVPQHENRMEYT-TPDEGHFRHKSSFVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *:*: * ** *:::: . .:****:**:*:* . *..********:: .:**:*:*:*.*** *: : :.* * *.:* *:* *****.* :*:* .**: *.* *:**** * * :* ::.**. : *:* *.**.*:. *.*::*. :* *.::..:* **:: :: * *:* * :*:*:*:*:*** * *:** :.* * *****::* **: *: : .: : :** : * ..: .** * : : ::* * :**.*********", "identical_positions": 121, "similar_positions": 93, "identity": "38.78%" }, { "cls_id": "homologset.agr.MGI:1933830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84039-1", "uniprot_id": "ENPP5_RAT", "id": "P84039-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "aln": "-----------------------------------------------------------------------------------------------------------------MIPEFLVVSCTLAALCHSVPLS---------------------------LQTEQQKVLVVSFDGFRWDYLYKVPTPHFHYVMKNG-------VHVKQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPVLNKSFSLEHMNIYDSKFWEE--ATPLWITNQRAGHA-----SGAAMWPGTDVKIH-----------------ESYPTHYLPYNESVSFEDRVAKIIEWFTA---KDPINLGFLYWEEPDDTGHDVGPDSPL------MGPVISDIDHKLGYLIKMLKKAKLWNNINLIVTSDHGMTQCSKER---------VIELDQYLDKEHYTLIDHSPVAAILPKEGKFNEVYDALAN---------AHPNLTVYKKEEIPERWHYKHSDR--------VQPIVAVADEGWYILQ---------------NKSDEFLLGNHGYD-NALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLVCHLLNVTALPHNGSFRNVQDLLSSAAPKAIPYTQSTTLPLGSAKPGEYEQEESYPYYIG--------------------ISLGSLIAIVFFVVLIKHLIRSQMHTLQYMQVEVAQPLLQA---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQG7-1", "uniprot_id": "ENPP5_MOUSE", "id": "Q9EQG7-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "aln": "-----------------------------------------------------------------------------------------------------------------MIPEFLLASCTLATLCHSAPFS---------------------------LQPEEQKVLVVSFDGFRWDYLYKVPTPHFHYIMKNG-------VHVNQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEE--ATPIWITNQRAGHA-----SGAAMWPGADVKIH-----------------DSFPTYYLPYNESVSFEDRVAKIIEWFTA---KDPINLGFLYWEEPDDTGHDVGPDSPL------MGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQR---------VIELDRYLDKEHYTLIDHSPVAAILPKEGKFDEVYDALAG---------AHPNLTVYKKEEIPERWHYKHNDR--------VQPIVAVADEGWYILQ---------------NKSDDFLLGNHGYD-NALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLLCHLLNLTALPHNGSFWNVQDLLSSATPKPIPYTQSTTLLLGSDKPGEDEQEESYPYYIG--------------------VSLGSIIAMVFFVVLIKHLIRSQVHTLQYRQVEVAQPLLQA---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJA9-1", "uniprot_id": "ENPP5_HUMAN", "id": "Q9UJA9-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "aln": "-----------------------------------------------------------------------------------------------------------------MTSKFLLVSFILAALSLSTTFS---------------------------LQPDQQKVLLVSFDGFRWDYLYKVPTPHFHYIMKYG-------VHVKQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEE--ATPIWITNQRAGHT-----SGAAMWPGTDVKIH-----------------KRFPTHYMPYNESVSFEDRVAKIIEWFTS---KEPINLGLLYWEDPDDMGHHLGPDSPL------MGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEER---------LIELDQYLDKDHYTLIDQSPVAAILPKEGKFDEVYEALTH---------AHPNLTVYKKEDVPERWHYKYNSR--------IQPIIAVADEGWHILQ---------------NKSDDFLLGNHGYD-NALADMHPIFLAHGPAFRKNFSKEAMNSTDLYPLLCHLLNITAMPHNGSFWNVQDLLNSAMPRVVPYTQSTILLPGSVKPAEYDQEGSYPYFIG--------------------VSLGSIIVIVFFVIFIKHLIHSQIPALQDMHAEIAQPLLQA---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QE68-1", "uniprot_id": "A0A2R8QE68_DANRE", "id": "A0A2R8QE68-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MPDFSVIRSCFLSCLLALLQTSGS-------------------------QQEEQNQLLLVSFDGFRWDYINRVPTPNFHALMDEG-------VLVEKVENTYITKTYPNHYTLVTGLHAESHGVVANEMYDPIHNRSFSIEGPEVYDAWWWEE--AEPLWVTNQKAGRK-----SGAAMWPGSDVAIG-----------------GTFPTHYLRYNASMLFETRVQKLIDWFSG---PEAINFGVLYWEEPDESGHNLGPESPL------MDVVLADIDEKLGFLREKLKSAGLYDKVNLIVTSDHGMTQLSHDK---------IIELDTYVSRDLYTWIDKSPVVGILPKEGKLEEVYGLLKN---------ANPNMVVYKKEEIPDHYHYRHNAR--------IMPLIIEVKEGWTVMQ---------------NRNGSFMLGNHGYN-NSLPNMHPVFVARGPAFRRDYTKTSMRSVDLYPLMCSILALKPLPNNGSLSSVQDLLVETS---TPKPTVTPVPRGPMVP-PVPREPSYAWAVG--------------------CILGAGLVIGFLFIFVKQVTQRQLPPLYLSNSEITQPLL-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHP---GVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED-------KYTVYVNGNFPKEWNFNDGKN------HHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQGYIEPFQN-TEIYNLLCDICGVAEKDRNS--NDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK-------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDNGPRTIANRSNTYFNGTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRP---NNLDARIWSN-TADPIWQLLQTESQG--EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIPNVDSYGHSFGYDLRD----KRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNNEVVPPFEN-IEVYNMLIKASALLGEEKTK--KEKS--LLQ---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. . : : :::*:***: : ** :: : . . . : : *:*:***:::*** .. **:*:* ::* . .* *. *.: : *:* * .: ****::* * :: :* :. :: ::: :. : :: . * : * ** * : :.::* : * : *: * . *:::.*****:: :: . : : . : * . . : : : : * : :. ::: . : : . : ::: :*.***: * :* .:*:. ** * . . ::* :: : .. . * . ", "identical_positions": 61, "similar_positions": 120, "identity": "7.98%" }, { "cls_id": "homologset.agr.MGI:1933831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PY28-1", "uniprot_id": "E9PY28_MOUSE", "id": "E9PY28-1", "name": "", "aln": "MAAGGSG-RASCPPGVGAG---AGSLGPSANAAAAPSN---------AAACAPVPPPPPSPPPGPGTDAQAVGDER--DDAGPG--ALLREPVYNWQATKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRVPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKHLRADNAFMLLTQARLFDEPQLASLCLESIDKNTADAIAAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENKRKVLGKALSLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BX70-1", "uniprot_id": "BTBD2_HUMAN", "id": "Q9BX70-1", "name": "BTB/POZ domain-containing protein 2", "aln": "MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *********.* .** ********:*: ***.*..* *.*..**********.* ** : **** ** **..*****:********************************:***********************************************************************************:***************************.*********:***************************************************:********.******************************************************************************************************************************************************************************************************************", "identical_positions": 481, "similar_positions": 21, "identity": "91.62%" }, { "cls_id": "homologset.agr.MGI:1933833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTX4-1", "uniprot_id": "NRG4_MOUSE", "id": "Q9WTX4-1", "name": "Pro-neuregulin-4, membrane-bound isoform", "aln": "MPTDHEQPCGPRHRSFCLNGGICYVIPTIPSPFCRCIENYTGARCEEVFLPSSSIPSESNLSAAFVVLAVLLTLTIAALCFLCRKGHLQRASSVQCEISLVETNNTRTRHSHREH--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWG1-1", "uniprot_id": "NRG4_HUMAN", "id": "Q8WWG1-1", "name": "Pro-neuregulin-4, membrane-bound isoform", "aln": "MPTDHEEPCGPSHKSFCLNGGLCYVIPTIPSPFCRCVENYTGARCEEVFLPGSSIQTKSNLFEAFVALAVLVTLIIGAFYFLCRKGHFQRASSVQYDINLVETSSTSAHHSHEQH--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LE13-1", "uniprot_id": "A0ABK0LE13_RAT", "id": "A0ABK0LE13-1", "name": "Pro-neuregulin-4, membrane-bound isoform", "aln": "MPTDHEQPCGPRHRSFCLNGGICYVIPTIPSPFCRCIENYTGARCEEVFLPSSSIQSKSNLSAAFLALAVLVTLAIVALCFLCRPQRALKTSPVKGIITYKGRLWTTQEKPHSDDFFIFRSNTTRRTRAVKYTNG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:**** *:*******:**************:**************.*** ::*** **:.****:** * *: **** : ::*.*: *. * .:.* :. ", "identical_positions": 71, "similar_positions": 22, "identity": "52.59%" }, { "cls_id": "homologset.agr.MGI:1933846", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03956-1", "uniprot_id": "MMP1_HUMAN", "id": "P03956-1", "name": "Interstitial collagenase", "aln": "---MHSFPPLLLLLFWGVVSHSFPATLETQEQ-------------DVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVP-------------------DVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFRE-----YNLHRVAAHELGHSLGLSHSTDIGALMYPSYT-FSGDVQLAQDDIDGIQAIYGRSQN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVQPIGPQTPKACDS-----------------------KLTFDAITTIRGEVMFFKDRFYMRTNPFYPE----VELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFM-KDGFFYFFHGTRQYKFDPKTKRILTLQK---ANSWFNCRKN------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EPL5-1", "uniprot_id": "MMP1A_MOUSE", "id": "Q9EPL5-1", "name": "Interstitial collagenase A", "aln": "---MPSLP--LLLLLWAASSYSFPVFHNGDRQ-------------NVETVWKYLENYYNLGKN-MQAKNVNGKEMMAEKLRQMQQLFGLKVTGNSDPETLRAMKKPRCGVP-------------------DVAPYAITHNNPRWTKTHLTYSILNYTPYLPKAVVEDAIARAFRVWSDVTPLTFQRVFEEEGDIVLSFHRGDHGDNNPFDGPNYKLAHTFQPGPGLGGDVHYDLDETWTNSSEN-----FNLFYVTAHELGHSLGLTHSSDIGALMFPSYTWYTEDFVLNQDDINRIQDLYGPSPN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIQPTGATTPHPCNG-----------------------DLTFDAITTFRGEVFFFKGRFYIRVNRFMPE----PELNLIGILWPNLPVKLDAAYEASMIDQVRYFKGSKVWAVQEQSVLRGFPRDIHSFFGFPSNVTHIDAAVCEEETGKTYFFVDHMYWRYDENTQSMDPGYPRLTAEDFPGIDDKVDDVFQ-KGENFYFFHQSVQHRFNLQIRRVDDSRD---SSTWFNC---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRS-MPDASKVERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQR-QIVFFIGREYYVFNSVMLAPGFPKPLAS-LGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMS-IWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCARSANEVDDEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P81563-1", "uniprot_id": "MMP1_RAT", "id": "P81563-1", "name": "Interstitial collagenase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTLKSEKNADFKDLY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:. :: :* ", "identical_positions": 2, "similar_positions": 6, "identity": "0.26%" }, { "cls_id": "homologset.agr.MGI:1933847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPL6-1", "uniprot_id": "MMP1B_MOUSE", "id": "Q9EPL6-1", "name": "Interstitial collagenase B", "aln": "---MPSLP--LLLRLWAASSYSFPVIQDGLQK-------------NVKTVWKYLENYYNLGKN-MQAKNVNGKEVMAEKLRQMQQLFGLKVTGNSDPETLRAMKKPRCGVP-------------------DVAPYAITHNNPRWTKTHLTYSILNYTPYLSKAVVEDAIARAFRVWSDVTPLTFQRVFEEEGDIVLSFHRGDHGDLYTFDGSKYHFAHAFLPGLGLGGNVHYDLDQKW-----TDNNEDFNLFYVTAHELGHSLGLSHSNDEEALMFPSYTWSNKDFVLNQDDINRIQALYGPSPN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIQLT-DATLDPCNS-----------------------GLTFDAIITYRGEVIFFKDRFYIRV-ISFLPEPLIDVIDLTWPNLPG---KFDAAYEVSGVDELRFFKGSKVWAVQEQNVLEGFPMDIQSFFGFPSNVTNIDAAVCEEETGKTYFFVDHMYWRYDENTRSMDPGYPRLIAEDFPGIDYKVDDVIQKED-NFYFFHQSIQYRFNLKTRRIDDS---SDINTWFNC---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRZ2-1", "uniprot_id": "D3ZRZ2_RAT", "id": "D3ZRZ2-1", "name": "interstitial collagenase", "aln": "---MLSLP--LLLLLLATSSYSLPVSQDGAQQ-------------NVETVWKYLEN---LGED-MQAKNVDVKEVMDEKLRQMEQSFGLKVTGNSNSETPSAIKTPMCGVP-------------------DVTPYSITYNNTQWTKTHLTYSILNYTPHLPRKVVEDAIERAFKVWSDVTPLTFERVFEEEGDIVLSFHQGDHGDLYSFNGSKSHFAHAFPPGPGLGGDVHYDLDETW-----TNNSDNFNLFYVTAHELGHSLGLSHSKDEEALMFPSYTWNNKDFVLNQDDISKIQALYGPSPN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIQPT-DATPDPCSS-----------------------GLTFDAITTYRGEVIFFKDRFYIRV-ISFLPKPLINVIDLIWPDLPS---KIDAAYEASLVDELRFFKGNKVWAVQEQNVLRGFPTDIHSFFGFPSSVTHIDAAVCEEETGKTYFFVDNMYWRYDENTRSMDPGYPRLIAEDFPGIDDKVDDVFQKED-NFYFFHQSTQHIFNLQTRKIVDA---PDSSSWFNC---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03956-1", "uniprot_id": "MMP1_HUMAN", "id": "P03956-1", "name": "Interstitial collagenase", "aln": "---MHSFPPLLLLLFWGVVSHSFPATLETQEQ-------------DVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVP-------------------DVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERW-----TNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSG-DVQLAQDDIDGIQAIYGRSQN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVQPIGPQTPKACDS-----------------------KLTFDAITTIRGEVMFFKDRFYMRT-NPFYPEVELNFISVFWPQLPN---GLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFMKDG-FFYFFHGTRQYKFDPKTKRILTL---QKANSWFNCRKN------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRS-MPDASKVERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQR-QIVFFIGREYYVFNSVMLAPGFPKPLAS-LGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMS-IWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCARSANEVDDEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * * . .:. : .. . . : :** : * :. :. . : * ::.::. .:.***: :. * :: * *** :* :: ..:* :*.**: : * : *: : *: :*:: : *** .* . :.** : * : * * *:*. :**** ** * **:.*:* *: * ::: *: *: *********:** *:*:* * . * :** ** :** . : *: * . .. :*** ***:::*:. : * . : * *. ** .:*.** :: ** * : :..: : *:* : * :*:* .:.:***:. ...:**: *** *: . .:: .**: :: :.*:. ::* .: . ***: *: . :: . *::* ", "identical_positions": 115, "similar_positions": 144, "identity": "15.09%" }, { "cls_id": "homologset.agr.MGI:1933945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925B5-1", "uniprot_id": "SYT13_RAT", "id": "Q925B5-1", "name": "Synaptotagmin-13", "aln": "-------------------------------MVLS--------------------------------------VPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDREPDPEKARPGVLQAAQQFN-----------------------VKKSTEPVQP-----RPLLKFPDIYGPRPAVTAPEVINYADY-----------------------------------------TLGTTEESAAPASPQAQSDSRLKRQVTEELFILPQNGVVEDV-CVMETWNPEKAASWNQAP-------------------------------------------KLHFRLDYDQKKAELFVTSLEAVTSD-HEGG--CDCYIQGSVAVKTGSVEAQTALKKRQLHTTWEEGLTLPLGEE-----ELPTATLTLTLRTCDRFSRHSVIGELRLGLNGASVPLGTAQWGELKTTAKEPSAGTGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQAQKLKKKQT--KRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQGEEGPSCELGRCSLGLHASGSERSHWEEMLKNPRRQIAMWHQLHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQT6-1", "uniprot_id": "SYT13_MOUSE", "id": "Q9EQT6-1", "name": "Synaptotagmin-13", "aln": "-------------------------------MVLS--------------------------------------VPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDREPDPEKARPGVLQAAQQFN-----------------------IKKSTEPVQP-----RPLLKFPDIYGPRPAVTAPEVINYADY-----------------------------------------TLETTEESAAPASPQAQSDSRLKRQVTEELSIRPQNGVVEDV-CVMETWNPEKAASWNQAP-------------------------------------------KLHFRLDYDQKKAELFVTSLEAVTSD-HEGG--CDCYIQGSVAVKTGSVEAQTALKKRQLHTTWEEGLALPLGEE-----ELPTATLTLTLRTCDRFSRHSVIGELRLGLDGASVPLGAAQWGELKTTAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQAQKLKKKQT--KRAKHKINPVWNEMIMFELPDDLLRASSVELEVLGQGEEGPSCELGHCSLGLHASGSERSHWEEMLKNPRRQIAMWHQLHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L8C5-1", "uniprot_id": "SYT13_HUMAN", "id": "Q7L8C5-1", "name": "Synaptotagmin-13", "aln": "-------------------------------MVLS--------------------------------------VPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQQFN-----------------------VKKSTEPVQP-----RALLKFPDIYGPRPAVTAPEVINYADY-----------------------------------------SLRSTEEPTAPASPQPPNDSRLKRQVTEELFILPQNGVVEDV-CVMETWNPEKAASWNQAP-------------------------------------------KLHYCLDYDCQKAELFVTRLEAVTSN-HDGG--CDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEE-----ELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQT--KRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z749-1", "uniprot_id": "A0A8M6Z749_DANRE", "id": "A0A8M6Z749-1", "name": "", "aln": "-------MCLLSSLLLCKHGVTSSLKCGFAPLVFSSSLHSVC----------------VCVCLVVCSWAGMLVSATALLGATLGTVSGVLTLCGLSLLCKSCK--KGKLESGDEADPEKAKPSILHTLTQFS-----------------------VHKCTEPIQP-----QASLKFPQIYRPKPSVTSQEVINYK------------------------------------------------EHGASNDTSAAELDTCNQATEREEVFSLPRQASADEIPCSSEQTGAMTTSSSILYP-------------------------------------------KLHFSISLHKESGELHINIVEAENIS-VEAG--CEGYISGCVSVSEEQKHAHTAVHKLAVHVQWGEELVFALPMESTEDTDSLDGEVALSLHCCDRFSHNSTLGMMRFKLADVSMMLDADCWVDLQPPKQEVTSSTGELLLSLSYLPAANRLGVVVMKARGLQSDKLKDNI--DLSVKLTLKHQNAKLKKKQT--RRVKHKMNPVWNEMMMLELPSELLAKSSVDLEVLNLASPGTLLPLGRCMLGLQTSGTGLQHWKQMLDNPRKQIAMWHPLYT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUJ3-1", "uniprot_id": "Q9VUJ3_DROME", "id": "Q9VUJ3-1", "name": "", "aln": "MSGLGPAACWLAHKRIESWSRMAKERVGAVRRVTLDRNSADEGTPSGSGASSTAGGNGVSVVHILPIGEGSTTPPPQPMTPPPSASSVTSTTSGIGSVSAGSVSDSCDLPTDSEEVAIAKECQPIQPASQLHGMHGGMGLNHHHMGTVSATGTDILRGPAEVFHSPLHLHHQSRSFPPRLQRTPSISSQSSVDSAPSRHSGHRGSSPQIRTFGPDGRSSLPSEPGFPHHLARSPSPMRTISLDARCGSPAHSADPGDLRTPSPSQSSLASLAGGSGMGGSSAGKGVAGGRCLSPLLIPPRSQPGVDPAMGPASPLGALQPDLYRMPDGPVYLTAPESSHAVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPYVRLMLQPEVDSRKRQTHIHRGESNPYFDQHFKFPVSRD-----QLQGKELILQVLDYDRYSHNDIIGEVRISVDGLDLSKSVEIWGDLLRTKK-PKEDRPELLCSLNYLPQAERLTVVIMKARNLDTLQ-------EPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFNLQSNYLHNAAIEIYVVGAGSEAT--EIGCCGLGPQESGTGCQHWHDMINNARKPTAMWHYIR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : .. .: : : .*: :. . * . : . : . *: :: :* .:. : .** *:::: . :: . : . * ..: . . . . :. * :** :. . . :* : :** . . : * : *: : . . :* ::: : : : : :.: : : : * : **:*::. * :*: : . .: .. * :* . : . . *:* *:.*** *:** **::**:.*.: : : **: * :: ::***:* : .. **:*** : ::* .: * ::::: *:. . . :* * ** : **: .**.:*:.*.*: **** : ", "identical_positions": 70, "similar_positions": 141, "identity": "11.33%" }, { "cls_id": "homologset.agr.MGI:1933946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2W6-1", "uniprot_id": "PTVO1_RAT", "id": "Q5U2W6-1", "name": "Prostate tumor-overexpressed gene 1 protein homolog", "aln": "MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRS-------RSWPAGPRGPQPP-------------------------RIRARSAPPMEGARVFGALGPIG--PSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSAAKLKRTLPCQAYVNQ-GENLETDQWPQKLIMQLIPQQLLTTLGPLFR-NSQLAQFHFTNRDCDSLKGLCRIMGNGFAG--------------------------------CMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVH---------------------------------------------------------------------SGPVQIVNNKFLAWSGVMEWQE----PRPEPNSRSKRWLPSHVYVNQGEI-LRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFT-KDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRRVIANQQQVLQRS------------------------------------------------------------------------------LEQEQQQRGMGG-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VU8-1", "uniprot_id": "PTOV1_MOUSE", "id": "Q91VU8-1", "name": "Prostate tumor-overexpressed gene 1 protein homolog", "aln": "MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRS-------RSWPGGPRGPQPP-------------------------RIRARSAPPMEGARVFGALGPIG--PSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSTAKLKRTLPCQAYVNQ-GENLETDQWPQKLIMQLIPQQLLTTLGPLFR-NSQLAQFHFTNRDCDSLKGLCRIMGNGFAG--------------------------------CMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVH---------------------------------------------------------------------SGPVQIVNNKFLAWSGVMEWQE----PRPEPNSRSKRWLPSHVYVNQGEI-LRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFT-KDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRRVIANQQQVLQRS------------------------------------------------------------------------------LEQEQQQRGMGG-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YD1-1", "uniprot_id": "PTOV1_HUMAN", "id": "Q86YD1-1", "name": "Prostate tumor-overexpressed gene 1 protein", "aln": "MVRPRRAPYRSGAGGPLGGRGRPPRPLVVRAVRS-------RSWPASPRGPQPP-------------------------RIRARSAPPMEGARVFGALGPIG--PSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQ-GENLETDQWPQKLIMQLIPQQLLTTLGPLFR-NSQLAQFHFTNRDCDSLKGLCRIMGNGFAG--------------------------------CMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAVGPGGVN---------------------------------------------------------------------SGPVQIVNNKFLAWSGVMEWQE----PRPEPNSRSKRWLPSHVYVNQGEI-LRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFT-KDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQVLQRN------------------------------------------------------------------------------LEQEQQQRGMGG-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PEH8-1", "uniprot_id": "MED25_DANRE", "id": "Q6PEH8-1", "name": "Mediator of RNA polymerase II transcription subunit 25", "aln": "MDPTSKSGLNQVSDVVFVIEGTANLGPYFESLRNNYILPTIEYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAFEFVSWIDSIQFMGGGAESCSLIAEGLSVALQLFDDFKKMREQIGQTHKVCVLLCNSPPYLLPAVESVSYTGCTADSLVQIIRDRGIHFSVIAPRKLPALRSLFERASSVAGLPESSHPDYSQDPFHMVLVRGIALPVAPGGGSVPVSLKPVLPPQSLPVNQNPLVPVASTAPQMNTFQNVSLHAAHDAAQKALEEAANQQQKNRFGQISTPPFSQSPVLPPGGKPSLSTVTTVSPPVLTQQQVPPQQPQQQTQVPQPGLPAVNQQPPQASQQQPNNQQTPPPTQPGMAAVPAPPPGAQQGVANKVVAWSGVLEWQEKPKASSMDSNTKLTRSLPCQVQVSQGEN-LNTDQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFLFTNKDMESLKGLFRIMTSGFAGCVHFPHSAPCEVRVLMLLYSSRKRIFMGLIPNDQSGFVNGIRQVITNHKQVQQQRSMQPGQVQPNQNFLNRPPGPIPVTHGNVPQQLRAAATGNQQAPVTGAPPNQVQGQAQAPGGGMLRLQNPGANPQLRSLLLSQQPQGGMQGMQGMHPIQQMVHAAPGGGAQMQPQWRQPHQGPLMVPTGPRGPVTQNPGMPSVSSVMEDEILMDLI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCB1-1", "uniprot_id": "PTOV1_DROME", "id": "Q9VCB1-1", "name": "Protein PTOV1 homolog", "aln": "---------------------MEPVPEEARGVGD-------------------------------------------------------DEGELDCLTHMIG------ALLLQKEPENPENGDSKETIWSGELEWEDAQILDQPKTLHTVQCKICSMVKEG-QPEINTENWPNKLKTQLIPKKVLGKIGEQFLKDARMVVFR--SSQGEVLNLLITAMSSGFAG--------------------------------CIHFPSNPNCNIKALILIYSRDHQALVGFIPNNEDSFSERLQEILQGAKRKPGVKTPKQ--------------------------------------------------------------PQPEEPPPVEEDAIINELLWTGSLNWST--QASLEEPSISHKLECSVYIAIKNGDPGISAEDWPTDMPMVLMPSIYLGQFAGAFIKDSKLIILRS-TPGEEHDSLASSMSAGSCGCARFSSEVVCKV--IMLLYSSPRNAFLGFIPRDQANFVKRLREVLDEHRQKARNKE----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: . : :* .* . . .. . : .. .. . .: . : .:*. : * : * : :. : . . : : *:* . * : * :. :: : ::.. : . . : . : : *:* ::*. . :.. . . : :.:*: : :::** : * *:*. * : * :. : : : . * ..* * * .**.:*. .. *:: :****** :. *:*:**.**..**: :*.*: :::* :. ", "identical_positions": 45, "similar_positions": 110, "identity": "6.41%" }, { "cls_id": "homologset.agr.MGI:1933947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0T0-1", "uniprot_id": "RTN1_MOUSE", "id": "Q8K0T0-1", "name": "Reticulon-1", "aln": "MAAPPDLQDEPLSLGSPGSQWFGGRGDGEDEATAVMGARPAQQDGEPAWGSGAGAGVTSSRELCSGPARSP---PVAMETASTGMAAVPDALDHSPSSTLK--DGEGACYTSLISDVCYPPREDSAYFTGILQKENGHITTSESPEEPETPGPSLPEVPGMEPQGLLSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPQEAKGQEEQHPGLEDKDLDFKDKDTEVSTKAEGVRAPNQPAPVEGKLIKDHLFEESTFAPYIDELSDE------QHRVS---LVTAPVKITLTEIEPP-LMTATQETIP----EKQDLCLKPSPDTVPTVTVSEPEDDSPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQVADKPKTKTRSGLPTIP-SPLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSG-----------PPPS-----PASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPGALDAIREETGSRATEERAPSHQGPVEPDPMLSFAPA--AALQSRPEPSSGDGASVPEPPRSQQQKPEEEAVSSSQSPTATEIPGPLGSGLMPPLPF-FNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64548-1", "uniprot_id": "RTN1_RAT", "id": "Q64548-1", "name": "Reticulon-1", "aln": "MAAPPDLQDEPLSPANPGSQLFGGRGEGEE--ATPKGARPAQQDGEPAWGSGAGAGVVSSRGLCSGPARSP---PVAMETASTGVAAVPDALDHSSSPTLK--DGEGACYTSLISDICYPPREDSAYFTGILQKENGHITTSESPEELGTPGPSLPEVPGTEPHGLLSSDSGIEMTPAESTEVNKILADPLDQMKAEACKYIDITRPQEAKGQEEQSPGLEDKDLDFKDKDSEVSTKPEGVHAPNQPSPVEGKLIKDNLFEESTFAPYIDELSDE------QHRMS---LVTAPVKITLTEIGPP-VMTATHETIP----EKQDLCLKPSPDTVPTVTVSEPEDDSPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQAADRPKVKARSGLPTIP-SSLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSG-----------PPPS-----PASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPGVLDAIREETSSRATEERAPSHQGPVEPDPILSFTP---VTLQSRPEPSSGDGAPVPEPPKSQQQKPEEEAVSSSQSPAATEIPGPLGSDLVPPLPF-FNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16799-1", "uniprot_id": "RTN1_HUMAN", "id": "Q16799-1", "name": "Reticulon-1", "aln": "MAAPGDPQDELLPLAGPGSQWLRHRGEGENEAVTPKGATPAPQAGEPSPGLGARAREAASREAGSGPARQS---PVAMETASTGVAGVSSAMDHTFSTTSK--DGEGSCYTSLISDICYPPQEDSTYFTGILQKENGHVTISESPEELGTPGPSLPDVPGIESRGLFSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPEEVKHQEQHHPELEDKDLDFKNKDTDISIKPEGVREPDKPAPVEGKIIKDHLLEESTFAPYIDDLSEE------QRRAP---QITTPVKITLTEIEPS-VETTTQEKTP----EKQDICLKPSPDTVPTVTVSEPEDDSPGSITPPSSGTEPSAAESQGKGSISEDELITAIKEAKGLSYETAENPRPVGQLADRPEVKARSGPPTIP-SPLDHEASSAESGDSEIELVSEDPMAAEDALPSGYVSFGHVGG-----------PPPS-----PASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPSALDAIREETGVRA-EERAPSRRGLAEPGSFLDYPS---TEPQPGPELPPGDGALEPETP-MLPRKPEEDS-SSNQSPAATKGPGPLGPGAPPPLLF-LNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPGAKRHAE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R540-1", "uniprot_id": "F1R540_DANRE", "id": "F1R540-1", "name": "Reticulon", "aln": "MSEKPEADSE-------GS-WYGEDFEKIDRFGRTSSAR-RDVLGEERQTRDWEDESSVEKQFSSHPESDRQPLPVVMETAST---------DKSTSSIQKSSDDRDDLYTSLLSNQHYSSHEDTSYFSGSLSKSADKHTTHTDD-----------FISGSYSVTFSSDSSNKIKTSTDQIDS----SHSTERAFGSSYNYMDISGKDDSRSSQRP---LEDWSMSGLSEPS-LYTKLE--KSPS-PVEVDADELGSAGLLDTQTFPYVEEPSDEELSDYQPYRSPGTGSSASPVRITLTEIPPTSVSPTTIQHSPTVTVSQKESILSLGLEGMPTVTLSEPEDDSPESSTPPTEDSESPMDPNIQAG---ETEIMNSIPDSTQAS--TIPPAQPASKKDSSPVENMSAPKSTLPPTSQGFEGNSAESGDSEIELVSEEP--SPRAPSSGYMSFSKTPATALPTIVASTAPVPSSTTAIPKSLALQYSILREEREAELDSELALESCG-----EESPKRLTHGSSKRYKEIPQAVKKPTSPTSATKEPFVTSTTPSTTILAPTSASKEKMSTMEEKPKHSTILSPGLPELKVEHPAGEVHKKERRRSSQARRGSEKTSAPPAVFQGFSREKAMELLYWRDLKKSGLVFGSLLLMLFSLTQFSVVSVVAYLALASLSATISFRVYKSVLQAVQKTDEGHPFKVYLDVEMSLSHDQMQKYAENVQYYINSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLIMVVVCMFSMPVVYEKYQAQIDQYVDLIRTQVNSVVAKIQEKVPGTKRKAE---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JHT6-1", "uniprot_id": "E1JHT6_DROME", "id": "E1JHT6-1", "name": "Reticulon-like protein", "aln": "------------------------MDRNFDELKKEAAATNEDIFKQAQRAYEDSALGGDTGNVSGGAQDDN------------------------------------------AHTEHYFANEQKKLDFGDAQEFVQRLAADAKD-----------------------AKLDLDTKFAQKTDDFEDFLRDAGKEVKQGISGLTTDFMNAERGFSAPLAPFSETVAQAPVIPAQAPAVPDHAPAVPAPVAPAPAVPAPLPVEEDLLGSFTDQPSAP-----------------------LQAFQPT--APSTANFYD----DEEDDFLGKPTTAAPAAPVAPLTKANQDSDTESPSVSYTPSPAKKPIVDALKDQDNEKFISSEDLASDFKEEPRSAPTPAPAPAPILDAAPAVAP---------------APVAVPVSVPVAKPQPVP--------------------------------VAVPVTTALITDLDDEEVVFKPTVQEAP-------------------------------------KAPTIAAPVVE-----------------PKPEPPKPKVEPAKPKVVPVAPVESTQPQPKIASVEEIFCKYGLDAWFKPER--LHPQVESLIYWRDVKKSGIVFGAGLITLAAISSFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPIGNKKPEAAAESEKDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12443-1", "uniprot_id": "RTN2_YEAST", "id": "Q12443-1", "name": "Reticulon-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRNTTTNKNANLNNSRNANAPGEAGHQNKTGLIYWTNPSKS-----------------------GASFAATLVSLLILRNVN-----VISVLLKIGYMVLFTSFAVELSTKVLFDKGVVSRFGMQESPDLVGVLKPHIDRELDRLPALEDRIRKLVFAHRTRNNFTIGVSLYFLHGLFAIF----------------SMNTVLIMTTIFLYTVP----------------------------------LIYDRKQARIDRAIDRMKDLVIHRFH--------------------------------------------------------------------KNYNKVVEKTEPYIDKIIPPQTDEGSYSTSISNENKSSTSQRNKSGLSS-------SEFDNMNDTSASKSGKDSYSTSQYNRAEYPVSQNENIGTLKSGKQEIPT-----------EKDFNNRHENFSKPDVKTYDPRTVDIEEELAAHQRELEQNLK------------------------DGDYNLVGSKEIPDPITVPAPTRHTTKPAESQSIPIKNNETLHKTTHGLKQKLQHA--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : .. . . * : . . . : :. . : . . . : . :. . * * . .: .* . : .: :.:.* . :* : :. :.: .: .: : . ::. . : . : . .:*: .. :* : : .. * : . . : . : . :: : ", "identical_positions": 10, "similar_positions": 79, "identity": "1.21%" }, { "cls_id": "homologset.agr.MGI:1933966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPF2-1", "uniprot_id": "MUC18_RAT", "id": "Q9EPF2-1", "name": "Cell surface glycoprotein MUC18", "aln": "--------MGLPRLVCAFLFAACCCCRSATGVPGEEKQPTPTPDPVEVEVGNTALLKCGPAHPSGNFSQVEWFLIHKE---RQIPIFRVHQGKGQSEPGEYEHRLSLHGP--------GATLALSQVTPHDDRMFLCKSK--QPRPQDHYVQLQVYKAPEEPTIQANVLGIHVDIQELKEVATCVGRNGYPIPQVIWYKNGRPLQEEENRVHIQSSQTVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNRMKESKEVTVPVLYPAEKVWVEVEPVG-LLKEGDHVKIRCLTDGNPQPHFTINKKNPSTEEMEEESTDENGLLSLEPAQKHHSGVYQCQSLDLETTVM-LSSDPLELLVNYVSDVQVDPTAPEVQE-GDSLTLTCKAESNQDLEFEWLRDKTGQLLGKGPILQLNNVKREAGGRYLCVASVPSVPGLNRTRRVSVGIFGSPWMAAKER--KVWAQENAMLNLSCEASGHPQPTISWNINGSATEWNPDPQTVVS------TLNVLVTPELLETGAECTASNSLGSNTTVIILKLVTLTTLTPDSSQTTGLSTPTVSPHSRANSTSTEKKLPQQESKGVVIVAVIVCTLVLAVLGATLYYFYKKGKLPCGRSGKQEIT-----LPPTRKSEFVVEVKSDKLPEEMALLQGSNGDKRAPGDQGEKYIDLRH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2Y2-1", "uniprot_id": "MUC18_MOUSE", "id": "Q8R2Y2-1", "name": "Cell surface glycoprotein MUC18", "aln": "--------MGLPKLVCVFLFAACCCCRRAAGVPGEEKQPVPTPDLVEAEVGSTALLKCGPSRASGNFSQVDWFLIHKE---RQILIFRVHQGKGQREPGEYEHRLSLQDS--------VATLALSHVTPHDERMFLCKSK--RPRLQDHYVELQVFKAPEEPTIQANVVGIHVDRQELREVATCVGRNGYPIPQVLWYKNSLPLQEEENRVHIQSSQIVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNHMKESKEVTVPVFYPAEKVWVEVEPVG-LLKEGDHVTIRCLTDGNPQPHFTINKKDPSTGEMEEESTDENGLLSLEPAEKHHSGLYQCQSLDLETTIT-LSSDPLELLVNYVSDVQVNPTAPEVQE-GESLTLTCEAESNQDLEFEWLRDKTGQLLGKGPVLQLNNVRREAGGRYLCMASVPRVPGLNRTQLVSVGIFGSPWMALKER--KVWVQENAVLNLSCEASGHPQPTISWNVNGSATEWNPDPQTVVS------TLNVLVTPELLETGAECTASNSLGSNTTTIVLKLVTLTTLIPDSSQTTGLSTLTVSPHTRANSTSTEKKLPQPESKGVVIVAVIVCTLVLAVLGAALYFFYKKGKLPCGRSGKQEIT-----LPPTRKSEFVVEVKSDKLPEEMALLQGSNGDKRAPGDQGEKYIDLRH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43121-1", "uniprot_id": "MUC18_HUMAN", "id": "P43121-1", "name": "Cell surface glycoprotein MUC18", "aln": "--------MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAP--ELVEVEVGSTALLKCGLSQSQGNLSHVDWFSVHKE---KRTLIFRVRQGQGQSEPGEYEQRLSLQDR--------GATLALTQVTPQDERIFLCQGK--RPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRPLKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESREVTVPVFYPTEKVWLEVEPVG-MLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTNDNGVLVLEPARKEHSGRYECQGLDLDTMIS-LLSEPQELLVNYVSDVRVSPAAPERQE-GSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWMAFKER--KVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRVLS------TLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEIT-----LPPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4F9-1", "uniprot_id": "A0A8M2B4F9_DANRE", "id": "A0A8M2B4F9-1", "name": "", "aln": "--------MTYTALLLAG--LAVLTCKTWALVDVR------MEDVVEVTLKGQAKISCTYTLTEEAKMIIWFTKLPGKDQNRKRFYYSENQTEIIDQNHEYAERIKVSHSYDTEEERGSVVLILDDVQLTDEREFICMVHSVLNDVGEGRTHLKIYNSPSLPVIEREHTGISVSETEPSKVAQCKVDDGYPRPNITWYKGSFPLDPSDGEVKILESVTVKPSGLFRVESELHIKVKKEDEGAHFYCEVKYLMLGKARMTESSRFNVTVHYPTTNIKLSINPPDKLIKEGDTLELQCEGNGNP-QPIFSFRHGE-----RDLINEDNGILHLKNVKRSDSGEYVCESLDLDTGMN--YEDSLNIKVHYLDNIMVTPDETDPDQ-GHDITLTCNALSSLPTHTAWYKD--GKLLVERHVLELHNASYETTGKYMCEVMVLSLPELKKQKSVQVNVRGKPEIKEGIK-VNQMNKVNHPVNLTCYAQGYPIPNITWTLFDQQTGQIVPVLKIVNQMMDNSVHSLISVKATSDLIANCSATNELGTDDASQSIKAFVRVTTISPTSTTTEATEITVQPKS-----------PQKGGSGVIIAVIIICLLLIAIVGSVLYYLYKKGKLPCGRSGKKDFM-----KQKASKDDIVMEMKSGKS-EEAVLLQGVNGDKKSPTE-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TSS9-1", "uniprot_id": "A0AB32TSS9_DANRE", "id": "A0AB32TSS9-1", "name": "", "aln": "MDNFRNMALQNTSLLLIVLQICALAWQAWAQVDLR------MEDTVEVYMDDSAEIPCLYTFTQAPMMVMVQWFVRERDGVRVRISYSDLTMQKVDENTTYSDRISVRSNSDGE------TLTIQDVKLSDEREFFCQVSGFSAGSDERRTLLKVFDPPEPPVIEGALSGVSVSGESTAKIASCETRDGYPKPNITWYRDHIPIHPANGLVNVVTLVTRESSGLYTVQSDLHYKVTKEDKDAHFSCEVSYFVPGAVRTSESKGVNITVYYPTSSVEMWKESPQGLVKEGDTVEIHCQGDGNPPAPIIFNREQS-----DVELDSYEGLLVLKEVSRMDSGVYECHALDLDAVNNDEVLDTLQLTVHYLDPAVVVPKDSEVMLKGESLTATCNALSSLETSTVWFKK--GLEVGRGHIMQLQDATFDTAGRYDCEVTVPSLPGLLTSGSVHIIVQGAPQIKDAERDFELMEKVGAWVNLTCEVRGYPRPAITWSITGSQSQSWREVDKKE---TEDRIHSVVTLKVTTDTVAICNSTNDFGIETKIYNIKSIPFLQTPTARKTSVDN-------------------------SGVIIVVIIVSILLLAILGSVFYFLYKKGKLLCGRSGKQEIINAYSTKEKTNKDDIVVEMKAKKT-EESVLLKGINGEKKPPNDQHPEIINGVLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: . : * . : **. : . * : * : .. : : . : : : : * .*:.: .* : .* *:* *:* : *:::..*. * *: *: *. . ::* * :*** *:: **:. *:. .. *:: :.***: ::* * :: ***:.*:* **:.* : . : .** ..:.* **: .: : :. ::**** : ::* :*** : :. . :*:* *: . : .** * *..***:: :. :: *:*:. * * .: * .:* **:* *. * :. * : . :::*:: :: * * * . * :* * * : : * * : : : : . :**:* . *:* * *:*.: . : .:: : . *.::*.:* : :: . . . :. **:*..:*:. *::*::*:.:*::****** * ****::: : *.::*:*:*: * ** **:* .*:*:.* : ", "identical_positions": 131, "similar_positions": 191, "identity": "19.1%" }, { "cls_id": "homologset.agr.MGI:1933972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZXL0-1", "uniprot_id": "A0A8I5ZXL0_RAT", "id": "A0A8I5ZXL0-1", "name": "Transformer-2 protein homolog alpha", "aln": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSR--SHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTH--GGGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRY-RRSPSP-YYSRYRSRSRSRSYSPR----RY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFR5-1", "uniprot_id": "TRA2A_MOUSE", "id": "Q6PFR5-1", "name": "Transformer-2 protein homolog alpha", "aln": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSR--SHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYR--RRSPSP-YYSRYRSRSRSRSYSPR----RY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13595-1", "uniprot_id": "TRA2A_HUMAN", "id": "Q13595-1", "name": "Transformer-2 protein homolog alpha", "aln": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTH---SGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSP-YYSRYRSRSRSRSYSPR----RY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19018-1", "uniprot_id": "TRA2_DROME", "id": "P19018-1", "name": "Transformer-2 sex-determining protein", "aln": "---------MDREPLSSGR--LHCSARYKHKR---SASSSSAGTTSSGHKDRRSDYDYCGSRRHQRSSSRRR-----SRSRSSSESPPPEPRHRSGRSSR---DRERMHKSREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPR---GKAPRSFSPRRGRRVYHDRSASPYDNYRDR-YDYRNDRYDRNLRRSPSRNRYTRNRSYSRSRSPQLRRTSSRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**. *..: .** * : * *.* ... *..*. **. . *: :* :* * * ** *.* .** *:* .** :*.* ** :*:.. *:*****. *:::.:**:*.:***:. :::* * :* *****.*:***::.*:: * : ..*:*:********:***:********:*:** .: . . . . * * * **. ** ** :* * ***** *:* ** ***** . * **", "identical_positions": 112, "similar_positions": 71, "identity": "38.62%" }, { "cls_id": "homologset.agr.MGI:1933973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5R1-1", "uniprot_id": "RFOX2_RAT", "id": "A1A5R1-1", "name": "RNA binding protein fox-1 homolog 2", "aln": "--------------------------------------------------------------------------------------------MAEGGQAQQQPPQ-------LGPGAAARGMKRESEVELPVPGAGADGPEPGLSKRPRTEEAADEGMQ---------------------------GNQEPTTTP-------DAMVQPFTTIPFPPPPQNGIPTEY--------------------------------------------------------GVPHTQDY----------AGQTSEHNLTLYGSSQPHGEQSSNSPSNQNGSLTQTEGGAQTDGQQSQ-----------------------------------------------------------------------------------------------------TQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTP----YANG-----------WKLSPVVGAVYG-------------------------PELYAASSFQADVSLGNEAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRG----------------------AHLRGRGRTVYGAVR-AVPPTAIP-----------------------------AYPGVVYQDGFYGA-DLYGG----------YAAYRYAQP-ATATAATAAAAAAAAYSDGYG-------------------------------RVYTADPYH--------------------------------------------------------------ALAPAASYGVGAVAS------------------------------------LYRGGYSRFAPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP71-1", "uniprot_id": "RFOX2_MOUSE", "id": "Q8BP71-1", "name": "RNA binding protein fox-1 homolog 2", "aln": "--------------------------------------------------------------------------------------------MAEGGQAQQQPPQ-------LGPGAAARGMKRESEVELPVPGAGADGPEPGLSKRPRTEEAADGGMQNE----------PLTPGYHGFPARDGQGNQEPTTTP-------DAMVQPFTTIPFPPPPQNGIPTEY--------------------------------------------------------GVPHTQDY----------AGQTSEHNLTLYGSTQPHGEQSSNSPSNQNGSLTQTEGGAQTDGQQSQ-----------------------------------------------------------------------------------------------------TQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTP----YANG-----------WKLSPVVGAVYG-------------------------PELYAASSFQADVSLGNEAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRG----------------------AHLRGRGRTVYGAVR-AVPPTAIP-----------------------------AYPGVVYQDGFYGA-DLYGG----------YAAYRYAQP-ATATAATAAAAAAAAYSDGYG-------------------------------RVYTADPYH--------------------------------------------------------------ALAPAASYGVGAVAS------------------------------------LYRGGYSRFAPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43251-1", "uniprot_id": "RFOX2_HUMAN", "id": "O43251-1", "name": "RNA binding protein fox-1 homolog 2", "aln": "--------------------------------------------------------------------------------------------------MQNEP---------LTPGYHG------------FPARDSQG------------------------------------------------NQEPTTTP-------DAMVQPFTTIPFPPPPQNGIPTEY--------------------------------------------------------GVPHTQDY----------AGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLT-TEGGAQTDGQQSQ-----------------------------------------------------------------------------------------------------TQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTP----YANG-----------WKLSPVVGAVYG-------------------------PELYAASSFQADVSLGNDAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRG----------------------AHLRGRGRTVYGAVR-AVPPTAIP-----------------------------AYPGVVYQDGFYGA-DLYGG----------YAAYRYAQP-ATATAATAAAAAAAAYSDGYG-------------------------------RVYTADPYH--------------------------------------------------------------ALAPAASYGVGAVAS------------------------------------LYRGGYSRFAPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PK58-1", "uniprot_id": "A0A8M1PK58_DANRE", "id": "A0A8M1PK58-1", "name": "RNA binding protein fox-1 homolog", "aln": "------------------------------------------------------------------------------------------MLMSTDVASVMLPVSRGILDRDLDSGSAAVRGMKRGDPE--PEGAAAAGDSTGAECKRARMDGTEDIAQ---------------------------GSQDSMCGE-------EGAVVPFFPPPPPPPPQNGLSLEFSS---------------------------------------------------GGGGGSSVYSS----------SGQTEAVAGTSSGASNPSTQLSDASPQPDNQLVLVSNAVAIRE--------------------------------------------------------------------------------------------------------------DSSEAKGTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFESSGDAEKARERLHGTIVEGRKIEVNNATARVMTNKKMVSP----YANGDSLS-TLPYAGWKLSPMMGAMYG-------------------------PEFYAVPGFPYPTTAAAAA-----------------------------AASTAASFRG----------------------AHLRGRGRPVYGAVRAAVPQPAIP-----------------------------AYPGVVYQDGFYGATELYSG----------YTAYRYTQPTAVASPTAAAAAAAAAYSDSYG-------------------------------RVYAADPYAAALATP--------------------------------------------------------AAAAAAAYGVGAMAT------------------------------------LYRGGYSRFSPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NFQ7-1", "uniprot_id": "M9NFQ7_DROME", "id": "M9NFQ7-1", "name": "", "aln": "MSASAVEVTGNVPPVEFHMREHMVQAGVAPFPGAPAGYAAAPNPGAAVVAAAAAAQQQQQQQQQQQQQQQQAQQQQQQQVAGGPPSAADSLSMAVAAAAAKQSADP---VTQMKSGSEAAGSGNSNNNNTAGAGTGAPGAAGGLTTEYSSGGCGGGGASTANSVVVATSVSDVVNASLYMQQKTNLSTQTQTQYEYEYEYNGTSLAEPRVPGPIPHPLTNGHAVDQVQQPPVQQQHLQSSLPPQNVLSISTVLIANEAAESQQSSAMQNAGGGGNTGGGGGGGGGGTPSSPLSNSPSSATASQAGGCGLTLNGSATEGSMSGDTSPVASGEPLLQTPPAHQQQQQQQQPLLCSSPTSMQSSGTSVTGSSIASGTLAATSSSGVGLLPTTGLDSIANGGAPTGCAVVPASTSQVIAHLNAAAAAASGIVSPSANVATSLSSALVPAQSVAAVAAASLDAKSQPKRLHVSNIPFRFRDPDLRAMFGQFGTILDVEIIFNERGSKGFGFVTFANSNDAERARERLHGTVVEGRKIEVNNATARVQTKKVTAVPNVVLTKDGAIPAPALVCVQWPEAAVAAAMRGVAIQRGHVGVVGATPYHHPHHPHHHPALLAASAAAAQQQQQRQLAAAAVATAAVAQQQQQQQQAVVQQQQQQVAAAAQQQHQQQQQQQQQAVQQQQAVQQQQQHQQQQQQQQQQQHAAVAAAAAAASHPHMHAAHAHAHAHALGPQLAQLQAVAVPTAASNAAALQQSLAAAIQNPSGNPNAAAAAAAYAARLSAATGATQSPQTAAAAAAAASMAASANAANNAAALHGFAPVYYDPFLAAAASADPNLRFQAAKPVTEVPAAQPAAILNRRTVTTLNSNPHTINRIPVPQNVLATAPLLKTPLSQAQQQAYATAATTYTAVAARAAYGAAAAAAAQPALAGYATVAGYAREYADPYLGHGIGPVPGYGATMYRGGFNRFTPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .* . . : * .* . . * . * * * ** . : * . . :.*: * *:: .. ** .. : : : . ::*. ******************* ******.********************* .* **::***:****:*************** *:* . * :* * :.: .*: * * : *... **:: .: : : : : :.** *.. .: * * ... *:.: .* : .* *:* : . *. :. :******** . . *. :*.* * *. *:**..* *: :****:.**:**", "identical_positions": 135, "similar_positions": 92, "identity": "13.99%" }, { "cls_id": "homologset.agr.MGI:1933988", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924S4-1", "uniprot_id": "KREM1_RAT", "id": "Q924S4-1", "name": "Kremen protein 1", "aln": "MAPPAARLALLSAAALTLAARPAPGPRPSPECFTANGADYRGTQSWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKHGEAASTECNNVCFGDHTQPCGGDGRIILFDTLVGACGGNYSSMAAVVYSPDFPDTYATGRVCYWTIRVPGASRIHFNFTIFDIRDSADMVELLDGYTHRVLVRFDGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQATKEEPPQERPAINQTLAEVITEQANLSVSAAHSSKVLYVITSSPSHPPQTVPGSHSWVPSVGASGHRVEGWTVYGLATLLILTVTAVVAKILLHVTFKSHRVTASGDLRDCRQPGTSGEIWTIFYEPSTTISIFKKKLKGQSQQDDRNPLVSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N43-1", "uniprot_id": "KREM1_MOUSE", "id": "Q99N43-1", "name": "Kremen protein 1", "aln": "MAPPAARLALLSAAALTLAARPAPGPRSGPECFTANGADYRGTQSWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKHGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMAAVVYSPDFPDTYATGRVCYWTIRVPGASRIHFNFTLFDIRDSADMVELLDGYTHRVLVRLSGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQATKEEPPQERPAVNQTLAEVITEQANLSVSAAHSSKVLYVITPSPSHPPQTAPGSHSWAPSVGANSHRVEGWTVYGLATLLILTVTAVVAKILLHVTFKSHRVPASGDLRDCRQPGASGDIWTIFYEPSTTISIFKKKLKGQSQQDDRNPLVSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MU8-1", "uniprot_id": "KREM1_HUMAN", "id": "Q96MU8-1", "name": "Kremen protein 1", "aln": "MAPPAARLALLSAAALTLAARPAPSPGLGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGSNSWAPPMGAGSHRVEGWTVYGLATLLILTVTAIVAKILLHVTFKSHRVPASGDLRDCHQPGTSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPLVSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************.* .***************.************************************************************************************************************************************:*********.*******************************:*::***************************:***.*.:*********************.*: *************************************.*** ******:***:***************:*********.********.***:**.*.:**..*********************:***************.********:***:**:**:***:***:***********************", "identical_positions": 435, "similar_positions": 34, "identity": "91.97%" }, { "cls_id": "homologset.agr.MGI:1933993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70606-1", "uniprot_id": "KCNN1_RAT", "id": "P70606-1", "name": "Small conductance calcium-activated potassium channel protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRSHNGSVGRPLGSGPGFLGWEPV-DPEAG-RPRQPTQGPGLQMMA-KGQPAGLSPSGPRGHSQAQEEEEEEEDE---DRPGSGKPPTVSHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESLCSFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSLISLELAVCAIHPVPGHYRFTWTARLAFS-LVPSAAEADVDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSISSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQSRVRKHQRKFLQAIHQAQKLRTVKIEQGKVNDQANTLADLAKAQSIAYEVVSELQAQQEELEARLAALESRLDVLGASLQALPSLIAQAICPLPPPWPG-----------PSHLTTAAQSPQS-------HWLPTTASDCG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQR3-1", "uniprot_id": "KCNN1_MOUSE", "id": "Q9EQR3-1", "name": "Small conductance calcium-activated potassium channel protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSHSHNGSVGQPLGSGPGFLGWEPV-DPEAG-RPLQPTQGPGLQMVA-KGQPVRLSPGGSRGHPQEQEEEEEEEEEE--DKTGSGKPPTVSHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESLCSFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSLISLELVVCAIHPVPGHYRFTWTARLAFS-LVPSAAEADLDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSVSSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQGRVRKHQRKFLQAIHQAQKLRSVKIEQGKVNDQANTLAELAKAQSIAYEVVSELQAQQEELEARLAALESRLDVLGASLQALPGLIAQAICPLPPPWPG-----------PGHLATATHSPQS-------HWLPTMGSDCG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BE84-1", "uniprot_id": "A0A8M2BE84_DANRE", "id": "A0A8M2BE84-1", "name": "", "aln": "MRLVLVKPTNETGLLDSTGAARSERVPDHCN------------AKRHSAAGEAGMQHRYSGAVH--------QHHHQHAEHRGGPRQTALPLPKHS------------QESLPSPFSQEAP---VKSQGSN-----------PSLADCSKPSLSRQQS--VGGAAKTANCQQD-----HHCSCSCES---HEHQLLQH----QHHKP------PPSLQLQVQQ---------------QRLLRSSLP-NCCVRGS---------AELRSQQQRDNVSLRSGDPAHHAR----------ACTPDRCQGAR---NSVSPRSKSSP-LSSDSRLWLE-----ENKHRHEGYKVNADANRLSHAGSRPSLSHGGPQHPQIAMNSCKYNGGIVRPLGS-LGASRRNLA-ELDSETQPLQTLHTSGLEVVVSKGNGEDPSKQSSENLVTQRPCSAPHK-----------KNKDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFALKCLISLSTVILLCLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIHPIPGQYVFTWTARLAFT-YTPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVHVCERYHDKVEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQ---LRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQERSEELEKRIGHLETKLDSINSSLQALPGLLSQAIQQQQHHLLDGLTQRGFTLTRPSSQTSERSWASSVHRRRSPSTAPHTSSDSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIK5-1", "uniprot_id": "A0A8M2BIK5_DANRE", "id": "A0A8M2BIK5-1", "name": "", "aln": "MRHRHAGAVHQQHSNDADARDSPKEASCPVA------------PLFSLPPPPPSIKERSTSSHN--------NRHVQSCPDRGTRNDECLPLTGHCSLAQGARTDRQPYDNLPHPFPGASSGYQCHSEGSHSPQQRSSVSPQPSPSELLPPPLPSHISNTRDTRQKSANYKQD-----IVQRRVGEGGRRDQYQLLQQPCYNQQRDPSFKPLLPNSSQGHVNEREEAEKERQLIEPQAQLLLGSSLPINYCIGGSGQVCRNKQAPLLQHQHQQARAQEHSLQQQHSDRDSRYQEGKIALCQPYRCERALERNSSVSSSEASSPPYGSSSQLWPEPHDKEEKKNRAGKHKAHAERTKLSHAGSKASVSESSHSLPQIAMNSCKYNGGVVRPLGS-LAASRRNLA-EHDSETQPLQTLHSSGLEVVVSKGGGEDPSKASNESLVRE-SGNAPQK-----------KNKDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFALKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIHPIPGQYVFTWTARLAFT-YVPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQAQKLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQERSEELDKRIGTLEDKLDAVTGSLQALPCLISQAITQQQQDLLDGFVHR----FRPPSLGSDRSWTPS-RRRRSPSTAPHTSSDSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q92952-1", "uniprot_id": "KCNN1_HUMAN", "id": "Q92952-1", "name": "Small conductance calcium-activated potassium channel protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSHSYNGSVGRPLGSGPGALGRDPP-DPEAG-HPPQPPHSPGLQVVVAKSEPARPSPGSPRGQPQDQDDDEDDEEDEAGRQRASGKPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESLYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFT-YAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALPGLIAQAIRPPPPPLPP----------RPGPGPQDQAARSSPCRWT-----PVAPSDCG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVW5-1", "uniprot_id": "KCNN_DROME", "id": "Q7KVW5-1", "name": "Small conductance calcium-activated potassium channel protein", "aln": "MSIQKLNDTTNSGYVSSEETDSLLVSSSNPSKGGGRTALLRQVKSNSTNGPTTGASTSSSGSVSGGGGGSGSGGGSASGSAAGASKPTLMRQDRTSTYLTSPQQSQHARMGSEESMRGGASGAAGHDEDVEQGLVRSSIVPDIEVHEEDQEQHSQQLNATTMATMTNNQQQQQPTISIMNLSLKPGDSHSHSSSPGSHPNLGTSSYQNLASSIPPSVPSRCRACRNCSRRASTTPTTLIDRSASRDSVKSAFQQGNLSGSMAICISNSALPQQQQLQQQYHLQQQQQQHYQLQQHHLHQQQLQQSQQQVPPVLITSSPTNGSRIIRQSSQPESSSTAICCGPHSACVGHAHSHSHTVPNVSLKQLRESSGDGIAGIAADSLRINGGMRPFKQLRKPASTLSIPGSMKTPSIANREQISSGCNEEAAEALVGIHSDYPRYEMYMEERALTGGNTSRKPSTNSAKHKPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHD--EEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYA---LRKVKMDQRKLMDNANTITDMAKTQNTVYEIISDMSSRQDAIEERLTNLEDKMQSIQEHMESLPDLLSRCLTQHQERIEQRRN-----FLHPDTAAVAPIQAPT--PQSMFNAAPMLFPHSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* **.: . . .: . : .* : . :. * : : :.::**:*:********:*****::*****:*** *.*** ***** * * *** ***:**.*** *:: *** *:***::** ********* :*: * *** :*****:**.* * **::** . . .. . *: **:********: *******::*************::.****** *************** :* **:*:**:: ***:** * :*:*.:*** :****.:****:**:****:*: * *::*******:****:******:************** **:**:***************:***: : .:**.****** **: **.**::* *: *:***:.::**:*. *:::*:: : : :: *: ** ::: : :::** *:::.: * : * ....", "identical_positions": 260, "similar_positions": 123, "identity": "27.69%" }, { "cls_id": "homologset.agr.MGI:1934028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZNR9-1", "uniprot_id": "A0A8I5ZNR9_RAT", "id": "A0A8I5ZNR9-1", "name": "Netrin-G1", "aln": "MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDVCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPESFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLHAFHMDPKSVKDLSQHTVLEIICTEEYSTGYST-NSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATMCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTFVPALDSLSNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWYYGCQPNVCDNELLHCQNGGTCHNNVRCVCPDAYTGILCEKLRCE-EAGSCG-SDSGQGAPPRGSPALLLLT--VLLGTASPLVF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4G0-1", "uniprot_id": "NTNG1_MOUSE", "id": "Q8R4G0-1", "name": "Netrin-G1", "aln": "MYLSRFLSIHALWVTVSSVMQPYLFVWGHYDVCKSLIYTEEGKVWDYTACQPESTDMTKYLKVKLDPPDITCGDPPESFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLHAFHMDPKSVKDLSQHTVLEIICTEEYSTGYST-NSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATSCLYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWYYGCQPNVCDNELLHCQNGGTCQNNVRCACPDAYTGILCEKLRCE-EAGSCG-SESGQGAPPRGSPALLLLT--MLLGTAGPLVF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2I2-3", "uniprot_id": "NTNG1_HUMAN", "id": "Q9Y2I2-3", "name": "Netrin-G1", "aln": "MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTT-NSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCE-EAGSCG-SDSGQGAPPHGSPALLLLT--TLLGTASPLVF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6S1-1", "uniprot_id": "A0A8M3B6S1_DANRE", "id": "A0A8M3B6S1-1", "name": "", "aln": "MIFPLFLTLQASWLTVCQATQHYPATWGHYDLCKSQGYTEEGLTWYYMACQPEAADMTKYLKVTLDPPNITCGDPPETYCTLENPYMCNNECDAATDELAHPPELMFDIVGRNPTTFWQSTSWKKYPKPLAVNITLSWNKTIELTDDIVITFESGRPEQMVLEKSLDYGRSWQPYQFYATDCLDAFTMEPKTMKDITQHTLLDIICTEEYSRGYVWKNDKTVRFEIRDRFALFAGPKLHNMASLYGQLDTTKNLRDFFTITDLRIRLLRPATGATMVDENNLSRYYYAISDIKVHGRCKCNLHANSCIYDKEKLTCECEHNTTGPDCGRCKRNFQARAWSAGSYLPIPKGTANICMANYAGPVNCECYNHSNRCSYIEVLNAVICVSCKHNTRGQHCHLCKLGYYRNATAKPDDENICIDCNCNPFGSESDRCNGTGYCRCKEGATGAMCHECLPGYLWDNGCKSRVCDSELLRCQNGGVCVNYVRCQCPPAYTGLLCEKPRCEKEPGGCGGSDSGQASLHPPSLILLLLLGGVFLTEICWITVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. **:::* *:**... * * .*****:**: ***** .* * *****::********.****:********::*:: ***********:* ***********: **:*:*****::**:***** *******.*******:**********:**:*********:*****:******.** *:**::**::***:*:******** ** *.* ::***:****:****:*:*************:******:***********.* :*** :*:**:********:*********. *:**:.****************:**:*:*.*.**.************ :. . ****:.********::**:***************.**:***:***:*: ****:**:* ***:** *****:*:*.** *:**. *.***** * **:..***.***:*****.* * *** ** ****:**** *** *.*.** *:***.: * **** :* :.. ", "identical_positions": 374, "similar_positions": 105, "identity": "68.62%" }, { "cls_id": "homologset.agr.MGI:1934029", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZN39-1", "uniprot_id": "D3ZN39_RAT", "id": "D3ZN39-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "MPAVASVPKELYLSSSLKDLNKKTEVKPEK-TSTKNYIHSAQKIFKAAEECRLDRDEERAYVLYMKYVAVYNLIKKRPDFKQQQDYYLSILGPA-NIKKAIEEAERLSESLKLRYEEAEVRKQLEEKDRREEEQLQQQKRQEMGREDSGAAAKRSVENLLDSKTKIQRVNGEKSEGGAAAERGAVTAKELYTMMMDKNTSLIIMDARKIQDYQHSCILG--SLSVPEEAISPGVTANWIEAK----LSDDSKDTWKKRGSVDYVVLLDWFSSAKDLLLGTTLRSLKDALFKWESKAVLHHEPLVLEGGYENWLLCYPQFTTNAKVTPPPRSRPEEVSVSLDFTYPSLEEPVPSKLPAQMPPPPLEANEKAQLVTDQDGKPRPLVQSALAGPSVAPKAEASPIIQPVPATKNVPQVDRTKKPAVKLPEDHRMKSESTD------QSGRVLSDRSTKPVFTSPATMLTDEEKARIHEETALLMEKNRQEKELWERQQKEQKEKLRREEQERKAGKTQDAEERDFTENQHKAKDGQEKRDSKQTKAEDREPPADGAQDATGTQRQSKSEHDASDAKVSVE--GKRCPMSEVQKRPADVSSASSMSGELSAG-----------------------------KAQREPLTRARSEEMGRIVPGLPLGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSVPPSTPPTHKVKPQIPAERDREPSKLKRSYSSPDITQALQEEEKRRPAVTPTVNRENKPPCYPKAEISRLSASQIRNLNPVFGG-SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG--------QYRYISPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENND------HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS-KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDG---RWKQKLQTSVDFP---LENLDLSQYVIGPKS-----SLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV-SSVRSSAAYILFYTSLGPRVTEAAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U87-1", "uniprot_id": "UBP8_MOUSE", "id": "Q80U87-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "MPAVASVPKELYLSSSLKDLNKKTEVKPEK-TSTKNYIHSAQKIFKTAEECRLDRDEERAYVLYMKYVAVYNLIKKRPDFKQQQDYYLSILGPA-NIKKAIEEAERLSESLKLRYEEAEVRKQLEEKDRREEEQLQQQKRQEMGREDSGAAAKRSVENLLDSKTKTQRINGEKSEGAAAAERGAITAKELYTMMMDKNTSLIIMDARKIQDYQHSCILD--SLSVPEEAISPGVTASWIEAN----LSDDSKDTWKKRGSVDYVVLLDWFSSAKDLLLGTTLRSLKDALFKWESKTVLRHEPLVLEGGYENWLLCYPQFTTNAKVTPPPRSRAEEVSVSLDFTYPSLEEPVPSKLPTQMPPPPIETNEKALLVTDQDEKLRLSTQPALAGPGAAPRAEASPIIQPAPATKSVPQVDRTKKPSVKLPEDHRIKSENTD------QSGRVLSDRSTKPVFPSPTTMLTDEEKARIHQETALLMEKNKQEKELWDKQQKEQKEKLRREEQERKAGKTQDADERDSTENQHKAKDGQEKKDSKQTKTEDRELSADGAQEATGTQRQSKSEHEASDAKVPVE--GKRCPTSEAQKRPADVSPAS-VSGELNAG-----------------------------KAQREPLTRARSEEMGRIVPGLPLGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKVKPQVPAERDREPSKLKRSYSSPDITQALQEEEKRRPAVTPMVNRENKPPCYPKAEISRLSASQIRNLNPVFGG-SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG--------QYRYISPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNE------HLDDLQAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCRRRSRTFEAFMYLSLPLASTS-KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDG---RWKQKLQTSVDFP---LENLDLSQYVIGPKN-----SLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV-SSVRSSAAYILFYTSLGPRITDVAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40818-1", "uniprot_id": "UBP8_HUMAN", "id": "P40818-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "MPAVASVPKELYLSSSLKDLNKKTEVKPEK-ISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPG-NIKKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEKGAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILH--SLSVPEEAISPGVTASWIEAH----LPDDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSGKPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGG-SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG--------QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENND------HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS-KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDG---RWKQKLQTSVDFP---LENLDLSQYVIGPKN-----NLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV-SSVKSSAAYILFYTSLGPRVTDVAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDD8-1", "uniprot_id": "Q9VDD8_DROME", "id": "Q9VDD8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "----MAKLKKLHMSSNLDDLEKMSIIPDLRSKGMKILLNTARKLYMTAEEYRLDGDEELAYITYMKYFNMLTAIHKKSDYPSHKTTVRQMLGDTESNRRIMDTLEEIINSLRHRYAQQHQAPEPIAPDLVSNGRAG--------------------------------VDSPITQPTQYARLGLITCQDLYRRMQEK--SVLVMDCRPSADYEASHLTYYCAFNVPEELITPGMSAGRLQAR----LSSSAKASWASRSVKDSVVLMDWNTKDAQPATNTAISTLLDILKNWDPDVTYRAPIQIVEGGYEYFIMMYPTHCTNPSVQAP-QQNNNDIETIDDIEYPSIHDIT-----------------MKEDISAKDFRPRPDFN--RANKPAATRVNEQGISRPSPPAKPIAEIMRDQAEFLQRAEQNDEQLEKAS------------------------------KMWKRQAAEGDGLNATEDQELHFRILQLESKAQDYIVENNRLREELSRIQELHNVTQQLS-----------------QKEVEATRNIESKIRERQRLDEQHELERQERER----------------------------------------------------------------------------------------LLAIARETKKHYKSPT----------------PSGPPSPGRNLEDVHVVSDSLESLLQLTGDPDPTIAPN------KAEIPTFDRAMKP----QPRNVERTSQRVRDFSPVIGQNVGRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKT--NGQVIEEVAALIKELWNG--------QYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQR--------------EMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVCQLNQCMDMYFSGERIHGWN---CPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFP---LENLDMNPYIARAESRA--VTPKTYQLYAVSNHYGTMEGGHYTAFCKSANYGKWFKFDDQVVSALDS-SNVVSSAAYILFYTWLPPMQVPL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39944-1", "uniprot_id": "UBP5_YEAST", "id": "P39944-1", "name": "Ubiquitin carboxyl-terminal hydrolase 5", "aln": "-------------MGSEQALSEVVESAKERFGRLRHLVQKFLDDDDVPQECLP--LLQECAEIWSSYVDACQDITMQAPKEDANRLSKGFLRLNETAFLYYMIVYTLLEDTLPRLKEFSSNKDQNVRNLYGERIQLLHN-----------------------DPNIERIRNVIENYPKFIQLQTIEPGKLSSMLHFHGDALLLIDVRPRSEFVRAHIKCKNIICIDPASFKDSFTDQQIESVSLITSPHSDITFFSNRDKFKFIILYTDTQLHNNFQQRQTRILAKILSQNSVIKPLSGTKILILENGFSNWVKLGGAYQSSVSETAHLTSSSSTPAFGSPQVPTGLFNQK--------------------SLSPNKDKSMPMVSMNTQPLLTTVQRPQLPLYYSDLPIIPQPSPNRNSPTVQKFSPHPPTTLSKLN--------------------------------------------------------------------------------------------------------------TPSTIQNKANTVERISPDIRAAQAHA--------------------------------------------------------------------------------------------YLPPASNVFS----------------------PRIPPLPQQNLSSSRQTILNNSQVLDLD----------------------------------------------------------LIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGSKKHLKQLSDEEERMREKMSIRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPRVK-TCNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYKGPKKGWYFFDDSLYRPITFSTEFITPSAYVLFYERIF--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . *.: : : ::. . ..:* : . : .*. * :. . : :* . : :. * : . : : . : . : .* : : :::::* * :: : : : : :. ..: ::: . . : .*. . ::* : : : . ::*.*:. :: . :. . . . ..: : :: :. : .: : : . . .. * . : . . .. . : . . :* . : * . * ** : . . ..: :.**.*:** ****.***** .: .*. : * : *. .. :* : ::.. ::: : : : . ::: *: : : . ***.:*: :*:* **.**: :: . .*: * .. . * *: ** ** * ::* .*.: * *:::* **: :. . * : :*: : . *:: : *. * :: : *::.* :** *:::**** : : : :. .::: . : *.*:.*: * * : *****:: .. *: *** : :.. :.:**:*** : ", "identical_positions": 97, "similar_positions": 231, "identity": "8.41%" }, { "cls_id": "homologset.agr.MGI:1934031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TBE6-1", "uniprot_id": "P4K2A_MOUSE", "id": "Q2TBE6-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPERAQPPEYTFPSGSGAHFPQVPGGAVRVAAAAG-------------------------SGPSPPC--SPG-----------------------HDRERQPLLDRARGAAAQGQTHTVAVQAQALAAQAAVAAHAVQTHRER---------------------------------------------------------------------------------NDFPEDPEFEVVVRQAEVAIECS-IYPERIYQGSSGSYFVKDS---QGRIVAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFNRIGLP----------------PKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNR------------QLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCP------------------------------------------------------------------------MDNSSCR-----DTDWVMVREPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVP--FSQEIKDLILPKISDPNFIKDLEEDLYELFKRDPGFDRGQFHKQIAVMRGQILNLTQALKDNK--------------------------------------------SPLHLVQMPPVIVETARSHQRSASESYTQSFQ---------------SRKPFFSWW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99M64-1", "uniprot_id": "P4K2A_RAT", "id": "Q99M64-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPERAQPPEYTFPSVSGAHFPQVPGGAVRVAAAG--------------------------SGPSPPC--SPG-----------------------HDRERQPLLDRARGAAAQGQTHTVAAQAQALAAQAAVAVHAVQTHRER---------------------------------------------------------------------------------NDFPEDPEFEVVVRQAEIAIECS-IYPERIYQGSSGSYFVKDS---QGRIIAVFKPKNEEPYGNLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFNRIGLP----------------PKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNR------------QLLLQFERLVVLDYIIRNTDRGNDNWLIKYDYP------------------------------------------------------------------------MDNPNCR-----DTDWVMVREPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVP--FSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNK--------------------------------------------SPLHLVQMPPVIVETARSHQRSSSESYTQSFQ---------------SRKPFFSWW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BTU6-1", "uniprot_id": "P4K2A_HUMAN", "id": "Q9BTU6-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAG-------------------------SGPSPPG--SPG-----------------------HDRERQPLLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRER---------------------------------------------------------------------------------NEFPEDPEFEAVVRQAELAIERC-IFPERIYQGSSGSYFVKDP---QGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFNRIGLP----------------PKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNR------------QLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCP------------------------------------------------------------------------MDSSSSR-----DTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVP--FSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNK--------------------------------------------SPLHLVQMPPVIVETARSHQRSSSESYTQSFQ---------------SRKPFFSWW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PE18-1", "uniprot_id": "P4K2A_DANRE", "id": "Q6PE18-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPLRD-SNDFNY----GPAEPTSPRGGFGSTPGS--------------------------VVRLPAG--SPG-----------------------RSRERQPLLDRDRGASPR------------------------DPHR-----------------------------------------------------------------------------------NEFPEDPEFREIIRKAERAIEEG-IYPERIYQGSSGSYFVKDS---AGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFHRIGLP----------------PKVGSFQIFVEGYKDADFWLRRFEAEPLPENTNR------------QLQLQFERLVVLDYIIRNTDRGNDNWLIKYDYP------------------------------------------------------------------------MDTSSNR-----DSDWVLVKDPIIKLAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVV--FSQEIRDLVLPKLADPNFIKDLEEDLYELFKKDPGFDRGQFKKQVSVMRGQILNLSQAMRDGK--------------------------------------------TPLQLVQMPPVIVETARVPQRANSESYTQSFQ---------------SRRPFFTWW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VND3-1", "uniprot_id": "Q9VND3_DROME", "id": "Q9VND3-1", "name": "Phosphatidylinositol 4-kinase type 2", "aln": "MSGARDQTDPPLLQLEDEVDLIGDFAKDQPPPRNQLSPLLNGFESTSNQLTTKVEINTVGMGKRKTRRRGKKAREPMLLSVDDEDDEEEAQEERNHTNGLPPGEESAGGDAVIQKPQLDNLVMHYDDQIDDEDGEEAVLLKRSSNPRNQRLKGSAEDSIDSSSQQPPIICHIAPAKVASSALTSPLKTTSHTALARHPHDEADDICLVPEIDFEGMSTDAGSDNRESQPLLGGGNASHGSRISELLGGLGRGHDHVEFVSNTFGDDPLFSEIVAKAEGAIENG-VLPERIYQGSSGSYFVKDA---SHQCLAVFKPKDEEPYGRLNPKWTKWMHKLCCPCCFGRACLIPNQGYLSESGASLVDRKLNLNVVPKTRVVRLVAESFN-----------YARIDRQKAKLKKRIKEHYPSA--HFNRMSLP----------------LKTGSFQLFVEGYKDADYWLRRFESEPLPPSVAK------------SFQLQFERLVVLDYIIRNTDRGNDNWLIKYVAPKITTQVGGTGGRTMHGVVTPKLPNALGASKIVDLNEPPQASPKPTTGGRPSNHLAGGAATSAQQDSSSLASSEDEPSSRSPPTSEPDWNVVNSAFIRIAAIDNGLAFPFKHPDSWRAYPYHWAWLPQAKIP--FSEEIKEQVLPQLSDMNFVEEICTELLYLFQQDRGFDKRLFERQMSVMRGQILNLTQALRDGK--------------------------------------------SPVQLVQMPAVIVERS---SGSRFFSFTQRFQ---------------NKSPFFSWC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42951-1", "uniprot_id": "LSB6_YEAST", "id": "P42951-1", "name": "Phosphatidylinositol 4-kinase LSB6", "aln": "MSNEAYQHDHTVN---------------PHQKIVVNSYDWLQFRDEQDHCKSKNPITHASPGVGSNAQNSDIAEAPQVFHPSYQSLVN-------VPSESPRPDQTSG------------------------SNPAVGLLHNAEDKASGQEEEGSQYEIQYSVFRPLHAYPTKGLAYEQLRRK-----------------------------------------------------------------------------EEQEQRENFNHLVSDCIEAVETFGRELERIQTGSSGSYFVYGTRADESVPVGVFKPKDEEPYGPFSPKWTKWAHRTFFPCLFGRSCLIPNLGYICESAASLLDRRLETHLVPYTDTASIESFNFYDNRKKWVLGYNLQKKKQKKLGSFQLFLKEYINADEFFHKYPLPGMYSDVKHSFHRKSSGEDINHKPETTRNLTDETEPSKQINSSPISTESEENSKFEWTESSLSQFRLELEKLIILDYIMRNTDRGLDNWMVKLIKLS-------------------------------------------------------------------------NNKWR----------------LKLAAIDNGLSFPWKHPDEWRLYPYGWLYLPLQLLAKPFSEQMRSHFLPILTSTNWWEESYQEFLALFSRDQDFNVRMWKKQWAVLKGQAFNVVETLKDPRQGPLELVRRTRCQVIDEKMQVPCCPPPVSIFKNAIDEPIGSYSTSPMVLPSTPSTIPFHAHNQSNSNPVYYDSTLHPFANKTVIAERLQIVNSTPVFTWC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . * . * :.* . **.. . : : * :: .. *:* *** ******** .. :.*****:***** :.****** :: ** *** **: * **:.*:.***:*::*: ::** * .. : : .* .: * : :. .. *:: ** . . ... .* :::::.*:. . . .: *::*:*::****:****** ***::* . * :::*******:** ****.** **: * :** : **::::. .** ::. *: :: :: **.:* .*: :.:* :*::** :*: ::::* : :*: * . *..* : . : : . :: . *.*:* ", "identical_positions": 122, "similar_positions": 132, "identity": "14.9%" }, { "cls_id": "homologset.agr.MGI:1934129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACK0-1", "uniprot_id": "D4ACK0_RAT", "id": "D4ACK0-1", "name": "", "aln": "----------------------------------------------------MWNSSD----DNFSCYHESVLGY--RYFAVIWGMVVAATGTVGNVLTLLALAIRPKLRTRFN-LLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGAIFCRIFGLLLFTSNSVSILTLCLIALGRYLLIAH--PKLFPQVFSAKGIVLALVGSWVVGVTSFAP----LWNVYVLVPVVCTCSFDRV-RGRPYTTILMGIFFVVGLSSVGVFYCLIHRQVKRAARALDKYGLQEAS--MRSHQVSGTHEAVPGHFQELDSGLASRGPSEGISSEPVSAATTQTLEGDS---------------------------------------SEAGDQGMRKAAQQISERSLPEVHRKTGGAAGARRATDAPSEFGKVTRMCFA-VFLCFVLSYIPFLLLNILDARGRAPRVVHMVAANLTWLNSCINPVLYAAMNRQFRQAYGSILKRGPQSFRRFH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIM5-1", "uniprot_id": "GPR84_MOUSE", "id": "Q8CIM5-1", "name": "G protein-coupled receptor 84", "aln": "----------------------------------------------------MWNSSD----ANFSCYHESVLGY--RYFAVIWGVAVAVTGTVGNVLTLLALAIRPKLRTRFN-LLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGAVFCRIFGLLLFTSNSVSILTLCLIALGRYLLIAH--PKLFPQVFSAKGIVLALVGSWVVGVTSFAP----LWNVFVLVPVVCTCSFDRM-RGRPYTTILMGIYFVLGLSSVGVFYCLIHRQVKRAARALDQYGLHQAS--IRSHQVAGTQEAMPGHFQELDSGVASRGPSEGISSEPVSAATTQTLEGDS---------------------------------------SEAGGQGIRKAAQQIAERSLPEVHRKPRETAGARRATDAPSEFGKVTRMCFA-VFLCFALSYIPFLLLNILDARGRAPRVVHMVAANLTWLNSCINPVLYAAMNRQFRHAYGSILKRGPQSFRRFH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQS5-1", "uniprot_id": "GPR84_HUMAN", "id": "Q9NQS5-1", "name": "G protein-coupled receptor 84", "aln": "----------------------------------------------------MWNSSD----ANFSCYHESVLGY--RYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFN-LLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAH--PKLFPQVFSAKGIVLALVSTWVVGVASFAP----LWPIYILVPVVCTCSFDRI-RGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQAS--IHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDS---------------------------------------SEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFA-VFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NG08-1", "uniprot_id": "A0A8M1NG08_DANRE", "id": "A0A8M1NG08-1", "name": "", "aln": "----------------------------------------------------MWNDTDLLRNDSFSCASPSVEGY--RYFGVLLGSAVTIVGTIGNILTVLAFVTDANLRTRFN-VLIVNLAFADLLYCTILQPVSVDSYLHLHWRGGATWCRMFGLLLFLSNSVSIITLCLIAMSRYLVVAHRTSSCARLLLSQRGVAALLISSWVLGLASFAP----LWPVYVFAPQVCTCSFHRT-KGRPYTTVLLFLYFFLGLGFVGLFYFLIYRKVSVAAKAFLKYRPSRRS--SKRKQAEAEGTTD-------DSGIS-AGASTTQSCEISSDGAVAEQHGKQ---------------------------------------AQEGQTTTQNATQHASSETTSKASPVVIQNTPAAANSGEDNEFKRVTRMCFT-VFLCFVGCFAPFLLLNVADKKNRAPQVIHMICANLTWLNSCINPLLYAAMNRQFNQAYKDLLSKAAHPLRWFGRTHWFTSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NDM2-1", "uniprot_id": "GUTR1_DROME", "id": "Q9NDM2-1", "name": "Protein trapped in endoderm-1", "aln": "------------------------------------------MDQDMGMATGYFQDAD-MQMDEPAAATQSIYPHSATLFAAISACVFVTIGVLGNLITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLTAVRFFQESWTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIAC--HSRYSQIYKPKFITLQLLFVWAVSFLLLLPPILGIWGEMGLDEATFSCTILKK-EGRSIKKTLFVIGFLLPCLVIIVSYSCIYITVLHQKKKIRNHDNFQIA--AAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCFLVCFLPLMLAN---------------------------------------VVDDERNTSYPWLHIIASVMAWASSVINPIIYAASNRN----YRVAYYKIFA-LLKFWGEPLSPMPSRNYHQSKN-SKELSGVIRS---------TPLFHAVQKNSINQMCQTYSV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W534-1", "uniprot_id": "MOODY_DROME", "id": "Q9W534-1", "name": "G protein-coupled receptor moody", "aln": "------------------------------------------MSDETTISLEDGYPPLEALTTMVPPADATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAA-AFIISLCIADLLFCALVLPFQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITH--HGLYARIYKRHWIAVMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQTCSIMTDDHGHSSKTTLFITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNS--IPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKVADKNVEHPSLHICSYILLYLSACINPIIYVIMNKQYRKAYKTVVFCQPARLLLPFGKTNGASSAAEKWKDTGLSNNHSRTIVSQMSGGTGAASGAGTATGTAAVAVMQTPPEVQQAQALEMVSRGPDLISKSNLPQPNVTPPPPSVLTATPNGSNSNSLTLRLPLKKNNHCYTNSGFNSSTPSPSSGLGIGISSSSIYRPGVGSLGSGSASIRRITMVGDDIILEEEELPPTPPATSAPTTPAPPPPSSPLHPLSTDSSTTTISGGAVVAGSSAPKPATPTPHIYMNVDSPKRNQYYMDRNTNAVAPESDSGPANTSATVSISGSKLTAKMKFPKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W533-1", "uniprot_id": "Q9W533_DROME", "id": "Q9W533-1", "name": "G-protein coupled receptors family 1 profile domain-containing protein", "aln": "MFPPKSGPTPHPISIALPLSDPYATDHMADQDAVLPVPLSDSLDLDVDVDLNLNMNLN-LNVDDRRQVLFEGYSDELLTIAWVACIVFIIVGVPGNLLTIVALSRGRQTRNSTA-IFIINLSCSDLLFGCFNLPLAASTFKERAWTHSDLLCRLFPMLRYGLLAVSLLSVSLITINRYIIIAH--PRQYPRIYQRRYLALMVAGTWITTFSIMIPTWRGVWGIFGLDVSIGSCSIMHDRYGRSPKEFLFIAAFMVPCICIVICYARIFLLVRKAAIRAGTAGKTNVSDVTPSSAPQHQIQAMATPKKPEKVTTSSGEANEPIAGRPFVVEENLAYIDDN---------------------------------------ASTDSLPISYSIRRRDQDQQPPPVDANVVLKEREKERDRDQEKVSLGRSQTQLEMGKTHGKNPITTSLRTTSFTRFSPRKSHYASMGNTSNASSIYPGRMSAKDRRLLKMILVIFVWFVICYLPITVAKIWKSATEVHWFNIAGYLLIYLTTCINPLIYVLMSSEYRRAYWNLLRCHGSPDTQKQRNQANAKRKHLESNRQVKATT-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . * **::*::*: * :: .* :***: : *. : . * . *::: .: : .**:: : *::.**:::: : . : :. : * * * :*:: *:. . *: *.: : * *. * . : . . : . : : . . : . :. . ", "identical_positions": 28, "similar_positions": 67, "identity": "3.91%" }, { "cls_id": "homologset.agr.MGI:1934133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MT7-1", "uniprot_id": "GPR87_MOUSE", "id": "Q99MT7-1", "name": "G protein-coupled receptor 87", "aln": "MGLNLTLTKLPGNELYSQASHTANSTSEGHGKNSTLHNKFDTIILPVLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVRDAGFGPWYFEFILCRYTSVLFYANMYTSIVFLGLISVDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAILSLPNIILTNGQPTKENIHDCMKLKSPLGAKWHMAVTYVDSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSNLDRLLDESAHKILYYCKEMTLFLSACNVCLDPIIYFFMCKSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LXU3-1", "uniprot_id": "F1LXU3_RAT", "id": "F1LXU3-1", "name": "", "aln": "MGLNLTLAKLPGNELYSQASHTANSTIEGHGKNSTHHNEFDTIILPVLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVRDAGFGPWYFEFILCRYTSVLFYANMYTSIVFLGLISVDRYLKVVKPFGDSRMYSITFTKVLSICVWVIMAVLSLPNIILTNGQPTKENIHDCMKLKSPLGAKWDMAVTYVDSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDDSAHKILHYCKEMTLFLSACNVCLDPIIYFFMCKSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BY21-1", "uniprot_id": "GPR87_HUMAN", "id": "Q9BY21-1", "name": "G protein-coupled receptor 87", "aln": "MGFNLTLAKLPNNELHGQESHNSGNRSDGPGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWHTAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:****:***.***:.* **.:.. :* ***:* **:****:******:************************************************:*********:**************************:*************************:*******:**************::***** *******.**. *****:*******************************************************************:******:**:***:****:********************:***************************************", "identical_positions": 321, "similar_positions": 30, "identity": "89.66%" }, { "cls_id": "homologset.agr.MGI:1934134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TN38-1", "uniprot_id": "MRGRH_RAT", "id": "Q7TN38-1", "name": "Mas-related G protein-coupled receptor member H", "aln": "MEPLATTLCPQECTQTTRNETPNETTWSSEHVTKYTYISISLVICSLGLVGNGLLIWFLIFCIKRKPFTIYILHLAFADFMVLLCSSIIQLVNTFHIYDSTLVSYAVLFMIFGYNTGLHLLTAISVERCLSVLYPIWYHCRRPKHQSTVACTLLWALSVLVSGLENFFCILEVKPQFPECRYVYIFSCTLTFLVFVPLMVFSNLILFIQVCCNLKPRQPAKLYVIIMATVILFLVFAMPMKVLLIIGYYSNSTDASVWKSLPYLNMLSTINCSINPIVYFVVGSLRRKRSRKSLKEALQKVFEEKPVVASRENEVQFSLPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MT8-1", "uniprot_id": "MRGRH_MOUSE", "id": "Q99MT8-1", "name": "Mas-related G protein-coupled receptor member H", "aln": "MEPLAMTLYPLESTQPTRNKTPNETTWSSEHTDDHTYFLVSLVICSLGLAGNGLLIWFLIFCIKRKPFTIYILHLAIADFMVLLCSSIMKLVNTFHIYNMTLESYAILFMIFGYNTGLHLLTAISVERCLSVLYPIWYQCQRPKHQSAVACMLLWALSVLVSGLENFFCILEVKPQFPECRYVYIFSCILTFLVFVPLMIFSNLILFIQVCCNLKPRQPTKLYVIIMTTVILFLVFAMPMKVLLIIGYYSSSLDDSVWDSLPYLNMLSTINCSINPIVYFVVGSLRRKRSRKSLKEALQKVFEEKPVVASRENVTQFSLPS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ** * *.**.***:***********. .:**: :*********.**************************:***********::********: ** ***:*******************************:*:******:*** ************************************ **********:*******************:*******:**********************.* * ***.****************************************************** .***** ", "identical_positions": 285, "similar_positions": 23, "identity": "88.79%" }, { "cls_id": "homologset.agr.MGI:1934135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IYF9-1", "uniprot_id": "SUCR1_RAT", "id": "Q6IYF9-1", "name": "Succinate receptor 1", "aln": "----MAQNLSCENWLALENILKKYYLSAFYGIEFIVGMLGNFTVVFGYLFCMKNWNSSNVYLFNLSISDLAFLCTLPMLIRSYATGNWTYGDVLCISNRYVLHANLYTSILFLTFISIDRYLLMKFPFREHILQKKEFAILISLAVWVLVTLEVLPMLTFITSTPIEKGDSCVDYASSGNPKYSLIYSLCLTLLGFLIPLSVMCFFYYKMVVFLKKRSQQQATVLSLNKPLRLVVLAVVIFSVLFTPYHIMRNVRIASRLDSWPQG-CSQKAIKCLYILTRPLAFLNSAVNPIFYFLVGDHFRDMLFSKLRQYFKSLTSFRL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MT6-1", "uniprot_id": "SUCR1_MOUSE", "id": "Q99MT6-1", "name": "Succinate receptor 1", "aln": "----MAQNLSCENWLATEAILNKYYLSAFYAIEFIFGLLGNVTVVFGYLFCMKNWNSSNVYLFNLSISDFAFLCTLPILIKSYANDKGTYGDVLCISNRYVLHTNLYTSILFLTFISMDRYLLMKYPFREHFLQKKEFAILISLAVWALVTLEVLPMLTFINSVPKEEGSNCIDYASSGNPEHNLIYSLCLTLLGFLIPLSVMCFFYYKMVVFLKRRSQQQATALPLDKPQRLVVLAVVIFSILFTPYHIMRNLRIASRLDSWPQG-CTQKAIKSIYTLTRPLAFLNSAINPIFYFLMGDHYREMLISKFRQYFKSLTSFRT------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXA5-1", "uniprot_id": "SUCR1_HUMAN", "id": "Q9BXA5-1", "name": "Succinate receptor 1", "aln": "MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * :*:**** * *:***** **.***:.*:*** **:**:*.:*******:******:**:*******:**:***..: **************:*************:****::*:*****:*************:*.*****:**:*.:*... ::* .* *:****:*::.****:*********** ********:.:***:*.:* **.*.*:** .**::******:******:***:******.** * *:* .*:.:* :*********.:**:****:***:*:**:.::*: ******* ", "identical_positions": 217, "similar_positions": 76, "identity": "64.97%" }, { "cls_id": "homologset.agr.MGI:1934157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKV2-1", "uniprot_id": "CILK1_MOUSE", "id": "Q9JKV2-1", "name": "Serine/threonine-protein kinase ICK", "aln": "----------------------------------MNRYTTIKQLGDGTYGSVLLGRS------------------------------IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN-IVKLKEVIR--ENDHLYFIFEYMKENLYQLIKERNK-LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCM-----------------GPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTD----------------WPEGYQLSSAMNFLWPQCIPNNLKTLIPN-ASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQIGHPLGIISK---DSGKPQREVQDKTGPPPYIKP-APPAQAPAKAYTLISSRPSQASQPPQ-----HSVHPYKGDVSRTEQ-----LSHVQEGKPSPPFFPSLHNKNLQPKILASLEQKNGE------IKPKSRRRWGLISRSTKGSDDWADLDDLDFSPSLTR-------------IDVKNKKRQSDDTLCRFES-----VLDLKPSES--------VGTGTTVSTQASSQRRDTPTLQSSAKQHYLKHS-RYLPGINIRN---GVLPNPGKDFLPSNSWSSSGLSGKSSGTVSVVSKITSVGSGSASSSGLTGSYIPSFLKKEIG---------SVMQRVQLAPLAAPPPGY------SSLKAVRPHPGRPFFHTQPRSTPGLIPRPPAAQPVHGRIDWSSKYPSRR------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62726-1", "uniprot_id": "CILK1_RAT", "id": "Q62726-1", "name": "Serine/threonine-protein kinase ICK", "aln": "----------------------------------MNRYTTIKQLGDGTYGSVLLGRS------------------------------IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN-IVKLKEVIR--ENDHLYFIFEYMKENLYQLIKERNK-LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCM-----------------GPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTD----------------WPEGYQLSSAMNFIWPQCIPNNLKTLIPN-ASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQIGHPLGISTQ---DSGKPQKDVQDKTGPPPYVKP-APPAQAPTKAHTLISSRPNQASQPHQ-----HFVYPYKGEASRTEQ-----LSHVQEGQPNPPFFPSLHNKNLPPKILAGLEQKSGD------MKPKSRRRWGLISRSTKGSDDWADLADLDFSSSLTR-------------IDVKNKKRQSDDPLCRFES-----VLDLKPSEP--------VGTGTSVSTQASSQRRDTPTLQSTAKQHYLKHS-RYLPGINIRN---GVLPNPGKDFLPSSSWSSSGLSGKSSGTVSVVSKITSVGSGSTSSTGLTGSYIPSFLKKEVG---------SVMQRVQLAPLAAPSPGY------SSLKAVRPHPGRPFFHTQPRSTPGLIPRPPAVQPVHGRIDWSSKYPSRR------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPZ9-1", "uniprot_id": "CILK1_HUMAN", "id": "Q9UPZ9-1", "name": "Serine/threonine-protein kinase ICK", "aln": "----------------------------------MNRYTTIRQLGDGTYGSVLLGRS------------------------------IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN-VVKLKEVIR--ENDHLYFIFEYMKENLYQLIKERNK-LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCM-----------------GPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTD----------------WPEGYQLSSAMNFRWPQCVPNNLKTLIPN-ASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDSEKPQKGILEKAGPPPYIKP-VPPAQPPAKPHTRISSRQHQASQPPL-----HLTYPYKAEVSRTDH-----PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGE------IKPKSRRRWGLISRSTKDSDDWADLDDLDFSPSLSR-------------IDLKNKKRQSDDTLCRFES-----VLDLKPSEP--------VGTGNSAPTQTSYQRRDTPTLRSAAKQHYLKHS-RYLPGISIRN---GILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNSVGSSSTSSSGLTGNYVPSFLKKEIG---------SAMQRVHLAPIPDPSPGY------SSLKAMRPHPGRPFFHTQPRSTPGLIPRPPAAQPVHGRTDWASKYASRR------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL64-1", "uniprot_id": "Q9VL64_DROME", "id": "Q9VL64-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------MNRYITLTQLGDGTYGTVVLGQR------------------------------KDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPN-IVKLKEVIR--ENDTLYFVFEYMKENLYQMIKDRDT-HLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCS-----------------GPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDD----------------WPDGYRLASMIHFRYPDCIKVPLSSVVSR-CSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANVRLNSKYAASNGHPVQSVSNNVLPVQEKLQAVTELLHQTNNNMNSHSNLGKNNNLAPKNGGVPRKYQPKLSFLTTSEMGAGSHADSSSLVGGATVDGVPVPQHQNGGESINDIYLNRNISQLFGLPAGPQHQQQQQVHHPNVSFSTTSSRNAGAIYVNGSHLSYDTANMNAKNNAKFVVGASNGGYYVPVARPSLLGPDAKVYNVFSKVSASQAPPSLIVRQPQLQPEVAPAPMRLSGRSRAAAAVQDPKMGALKSDDLDLILGSKLKTSAKRQRNAKANILLEDLFGQLSMDSDSDGKYPHTVPPTQQAKSGKTSTGGHGAGARERDLFGESYLPRPGLRKKATQSSLEVNNGSHADSLAPNAQKEKPAVASSFPWDESNRTEDEKLTAWMVAENGNLILDNHQQA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32581-1", "uniprot_id": "IME2_YEAST", "id": "P32581-1", "name": "Meiosis induction protein kinase IME2/SME1", "aln": "MVEKRSRQSSSSGSEFSVPPDVDNPPLSIPLKTLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFFENTVASQVDAR---GNVTNTEQALIFAGINPVATN---TKPIYFNSSTKLPAETESND-----------------------------IDISNNDHDSHAMCSPTLNQEKLTLVEFLNEFVEED-------------------------NDDHSIPDVGTDSTISDS------------IDETELSKEIRNNLALCQLP------------------------DEEVLDHSLSNIRQLTNDIEIINKDEADNMEQLFFDLEIPE---------KDEFQRKQPFN----EHADIDEDIVLPYVNNSNYTHTDRSHHRGD--------------------NVLGDASLGDSFNSMPDF--------------TPRNFLIPTLKKSREKFEPHLSNSNQHFGNVTF--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** : :** *::* * *.: .: :*** * * :: :: .:**:* : : : :::: **: ** *::::* *::****::*.* :. . ::.*: *:* ** .:*.*.**********:* . ::*:*******.:..: *:* ********:**:**:* *...:*:**.**: .*: .:*.****:.*:* ::** .***** * . * :. .* ::: * *. ::. .: :::.. * :**.:*.**.: . *:*. : . . . . :. * : . . : . . .. . : . : :: ::. ..: : * : . : : . . . : : : :: . . . :: : . :. .. :. . *. : . :. . . . : . ", "identical_positions": 107, "similar_positions": 169, "identity": "13.24%" }, { "cls_id": "homologset.agr.MGI:1934229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A081-1", "uniprot_id": "D4A081_RAT", "id": "D4A081-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "-------------------------------------------------------------------------------------------------------------------MVLGVFKSQLSTGKQNSGESMSSLPGCMSLAAAPAAADSAE---------------------------IAELQQAVVEELG---------ISMEELRQFIDEELEKMDCIQQRK-KQLAELETWVLQKESEVAYVDRLFDD-----------------------------------------------------------ASREVTNCESLVKDFYSKLGLQYHDSSSDDEA--SQPTE-------IIEIPDEDDD----VLSIDSGDAGSRTPK---DQKLREAMAALRKSAQDVQKFMDAVNKKSSS------------------------QDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKSLLS---GNHIAYDYHPPADKLFVGSRVVAKYK----------DGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTSTG-IQFKPMEPLQPIVPPAP--LPMLPLSPQAGDSESLESQLAQSRKQVAKKSTSFRPGSVSSGHSSPTSPTLSENVPPGKIGMNQTYRSPSASVTSTPAPAAP------SGPPAPPGPLAPPGPPAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLYLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTVQATACTPGGQINPSSGYQHKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPSS-SDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKESELSEVTSKDSRAPDRGPPHVPITPSGSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDSKQSKKEDPEDRNKMSVVTEGSQNHGHNP-PMKSEGLRRPASKISMLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTTGQTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVR-----------KNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88974-1", "uniprot_id": "SETB1_MOUSE", "id": "O88974-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MSSLPGCMSLAAAPAAADSAE---------------------------IAELQQAVVEELG---------ISMEELRQYIDEELEKMDCIQQRK-KQLAELETWVLQKESEVAYVDRLFDD-----------------------------------------------------------ASREVTNCESLVKDFYSKLGLQYHDSSSEDEA--SRPTE-------IIEIPDEDDD----VLSIDSGDAGSRTPK---DQKLREAMAALRKSAQDVQKFMDAVNKKSSS------------------------QDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKSLLS---GNHIAYDYHPPADKLFVGSRVVAKYK----------DGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTGTG-IQFKPMEPLQPIAPPAP--LPIPPLSPQAADTD-LESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSSTLSENVSAGKLGINQTYRSPLASVTSTPASAAPPVPPVPPGPPTPPGPPAPPGPLAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPTS-SDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENELSEMTSKDSRPPDLGPPHVPIPSSVSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDNKQPKKEDPENRNKMPVVTEGSQNHGHNP-PMKSEGLRRPASKMSVLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTAGHTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVR-----------KNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15047-1", "uniprot_id": "SETB1_HUMAN", "id": "Q15047-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MSSLPGCIGLDAATATVESEE---------------------------IAELQQAVVEELG---------ISMEELRHFIDEELEKMDCVQQRK-KQLAELETWVIQKESEVAHVDQLFDD-----------------------------------------------------------ASRAVTNCESLVKDFYSKLGLQYRDSSSEDES--SRPTE-------IIEIPDEDDD----VLSIDSGDAGSRTPK---DQKLREAMAALRKSAQDVQKFMDAVNKKSSS------------------------QDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLS---GNHIAYDYHPPADKLYVGSRVVAKYK----------DGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASALEKKQG-QLRTRPNMGAVRSKGPVVQYTQDLTGTG-TQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSD-LESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPA------------------PSALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCS-SDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVR-----------KNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BR4-1", "uniprot_id": "STB1B_DANRE", "id": "Q08BR4-1", "name": "Histone-lysine N-methyltransferase SETDB1-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------M---------------------------EMELEPELEEELG---------VSLDELRKWIEEQVDSSEAVQKRK-ADLEQLQEWVEQREKEVADIDALCSN-----------------------------------------------------------ASESVVQCEALVKEVYSNMGLVYRESSSDDEGGKANPSE-------VIEIDDDDDDDVIAVGCLVPPKKSLTQAK---DPALKEASAALQRTSQQVQNLAQTVNRTAQSGVTTPVKTGGPPGQGPLAVPAVFMSSAPRNTPTQPNPNIKQD-SIKINMTLLGKKRTKTWHRGTLVAIKQVGNNLKYKVRFENKGKSLLS---GNHVAFEYHPTLERLFVGARVVARYK----------DGNQVWLYAGVVAEMPNSKNRMRFLIFFDDGYASYVGLPELYPICRPLKKTWEDIEDASCRDFIEEYITSY-PNRPMVLLKPGQIIKTEWEGTWWKSRVEEVDGSLVKMLFLDDK-RSEWIYRGSTRLEPMFNLKMNTANSQEKKMAGQQRQRPNMGALRTKGPVVQYTSDNSAAASTGGGAATPGTPTRPVAP--QPAGPPQPSRTESPSFKSQMAK--KSTGQLALQPRQGMPSDLQPKPIINALQTNTSR----LFLLQSGPVHTLTPITP---------------------APQTVQTAISTYTNERVPQEPSYQAPNDRLFYLTHNCSPECLKRIRPTRPNLHRGRNPLLTPLLYEFRRMTGRRRLNRKMSFHVIYKSPCGLSLRNMTEIQRYLFQTQCDFIFLEMFCLDPYVLVDRRFQPQRPFYFIRDITSGREDIPLSCVNEIDNTPPPSVAYSKERIPEDGVYINTSADFLVGCDCTDGCRDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECLPTGIYECNKRCRCNMQMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESEAHCSDSEGSGVDMSR-------VKLPASSRHGKSNK---MEE--------RNSSTTGKSQDDSSEESDDEKDDDSNEDD------------------SDSSDDT------------FVKDTYYTTSSVWRSYTTR-----RQAKGLKEESQDSKDGMSVSAGEDRKPPHMPEETGKSKVASWLTNQ-------------------SSTSANQSVKVEGGIKTEKKDVMTLS-------------------------DSDDVQTISSGSD-DNKEREKKTQAVVKRQVAVKSTRGIALKS-HSMMVKSG-GGGAGGGGSGPSHGHGGGGGDNGPKNTRLFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLLQIIKTEWEGTWW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32KD2-1", "uniprot_id": "SETB1_DROME", "id": "Q32KD2-1", "name": "Histone-lysine N-methyltransferase eggless", "aln": "MSGQPTAVDCLESSGSTVEDVQETPASREKSYGLPVRKGENSLESPAEQAAKDVEIEELTHSEAIAATGSTRKQCPYGGKAPDEPGKLADESEDRKGENTKAIASSPVLVAVDSDSSVELIESPVKFSSANESEKDPPKPDAVNEAAAKEAEEMTDSSISSPTSESFPEKDEKTNKENEQEPPGMEVDQDVEESISRPAEEYKIENTLKGHKRISLTEIEEHKIVDKKDDVLEVELEKGTAPKAAEDEKLNALLSDGDVFYDKECVNCNCTKLHKQYVLANMATLNFYQVLRKSSKQQFLCMGCHDTAMDLYEEYAGQLMAKQPLLLKDFHQDHADFVALDSSDEEEEEKQPEKSDFSKNKLQLIEDELDDAIKNVLNKVDFTAQLSWSKTILQAKADHLERQFALADVELEKVQTTADKMHCALYNSCPVAHKHLPTLDIEPSDYVHEVPPPGEIVRPPIQLGETYYAVKNKAIASWVSIKVIEFTESTAINGN-TMKSYKIRYLNTPYQMIKTVTAKHIAY-FEPPPVRLTIGTRVIAYFDGTTLSRGKDKGVVQSAFYPGIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVH-AASRDFIQKYVEKYSVDRPMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVFRETQNNMNS---------SSAQQLRVPRRTEPFIRYTKEMESSS-------KVNQQMRAFAR-----------KSSASAQNNALAAASSAATPAGGRTNAGGVSTSNSASAVRHLNN-------------------------------------------------STIYVDDENRPKGHVVYFTAKRNLPPKMYKCHECSPNCLFKIVHRLDS----YSPLAKPLLSGWERLVMR----QKTKKSVVYKGPCGKSLRSLAEVHRYLRAT-ENVLNVDNFDFTPDLKCLAEYSIDPSIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTYAKQRIPTEGVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCKKN-CLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAGDEYFADLDYIEVAEQLKEGYESEVDHS-----------------------------------------------------DPDAEEDNGGPDAEDDDDFRPN---------------------------------------------------------------YHYQRKIKRSSRSGSTQNSSTQSSELDSQER--------------------------------------------------------------------------------------AVINFNPNADLDETVREN---------------------------------------------------------SVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : *.:. ::. :: :::. . ::::. :*: . : * :: * .: *.. :.: *:*:.:.. . .**::* .* : : * *: ** * .* : . : : ::::. :.:: : . . : :: : . : . *. . **: .**::: *. .::. .:*:*: :.*. :* :*:**:* :. . * :*.*::** : *: *:***:****:.** :: :*:. :*.***:. :.****::*: * :**** . ** :.** :*** :** ::* *** : * .** : ******* ** *:* . .. .: :: . * . *.::**.: .:. . * .: :. :* . . . . * . :. . *. . : : : :* * ** ** :: . .** *** :.*:. * :* *:** *** .**.: *:.*** * :.: :: * : * : .:. .: **: *:*.:.:. ** *.* ** :*:*:*** .**.:* . :**: *** *.* *****:* ***: .. : . **::***.* :***:****.**.*. : * **:**..*:::**:***.*:***:**::**.**:*:*****::**: :*:: * : ******:**:** .*::******:. * .. :... : ..*. : : .: * .* . : . . : : .:...:: *: :: ..* ::. :*: **:*** ******:****************************:: :**:******:****** * ** * * **: :** *** ", "identical_positions": 297, "similar_positions": 307, "identity": "18.31%" }, { "cls_id": "homologset.agr.MGI:1934234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78356-1", "uniprot_id": "PI42B_HUMAN", "id": "P78356-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNH--------------------------------------------------------------------------TINELSNVPVPVM--------LMPDDFKAYSKIKVDNHLFNKE-NLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSD-SQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDG--------VETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEK-----AKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80XI4-1", "uniprot_id": "PI42B_MOUSE", "id": "Q80XI4-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNH--------------------------------------------------------------------------TINELSNVPVPVM--------LMPDDFKAYSKIKVDNHLFNKE-NLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSD-SQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDG--------VETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEK-----AKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEEEECENDGVGGSLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88377-1", "uniprot_id": "PI42B_RAT", "id": "O88377-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNH--------------------------------------------------------------------------TINELSNVPVPVM--------LMPDDFKAYSKIKVDNHLFNKE-NLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSD-SQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDG--------VETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEK-----AKDLPTFKDNDFLNEGQKLRVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEETEVEDRAEEEECENDGVGGGLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38994-1", "uniprot_id": "ITS3_YEAST", "id": "P38994-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase MSS4", "aln": "MSVLRSQPPSVVPLHLTTSTSRKTEQEPSLLHSAIIERHQDRSVPNSNSNPDSNHRIKKDRNNHTSYHSSSNSESNMESPRLSDGESSTPTSIEELNPTINNSRLVKRNYSISIDPLHDNSNNNTDDDHPNTITSPRPNSTSNKEMQKYSFPEGKESKKITTPSLNSNNCLDLDNSSLVHTDSYIQDLNDDHILLNKRVSRRSSRISAVTATSTTIKQRRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLHPLPQPSQKSKQYHMISKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAATGLKRSESATAEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNMLTGIRVAVSRCSGIMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHVRDNP-NTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKKDVELLAKLNTMDYSLLIGIHDINKAKEDDLQLADTASIEEQPQTQG-----------PIRTGTGTVVRHFFR--EFEGGIRASDQFNN---DVDLIYYVGIIDFLTNYSVMKKLETFWRSLRHDT-KLVSAIPPRDYANRFYEFIEDSVDPLPQKKTQSSYRDDPNQKNYKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * *::.: **. .. *:*: *::.:... : ..: *.** : * *:.: *.* * * **: .*: .* * : . ****:*** ***:** **:* ** *:* . :.. * *:.*: * : * :::***: .: .::: :::*::.: : ***: ** *::*:.: : *::* .*:*. :* :* .******* .* :. .:: . *.:** ::*:****::.* .**.** :**:***:**:*: ******:****:::*:::: :: : *. ** : * .*. . :** **: .: . .: . :*::.***:** *.. ** ::::*.: :*:: *.:*::** **:.: : ", "identical_positions": 128, "similar_positions": 150, "identity": "16.06%" }, { "cls_id": "homologset.agr.MGI:1934254", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99N75-1", "uniprot_id": "Q99N75_MOUSE", "id": "Q99N75-1", "name": "Prolactin-induced protein", "aln": "MASLQMFYQPGALMHLLILCLFLETPYGQENWNNPLSLDMIVSP-MKGKNEFTVTLQVKNNVGQCMVVKVSTVMNPSIKYLSAHAIYTSCLCSAN--KYFWDIQVSDNTALQGKAEVVPAKSICPDDEKIFPVTSYVETATQKIIVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99N74-1", "uniprot_id": "Q99N74_RAT", "id": "Q99N74-1", "name": "Prolactin-induced protein", "aln": "MASLQMFYQPRAAMHLLILCLFLETAYGQDIWSNPLSLELIVSP-LKKANEFTVTLQVKNNVDQCMAVKVSTVSNPNIKYISSHAIYTSCLCDVN--NYFWDIQVIANTALQGKAEVVPAKDICPNDENIFPVTSYIGTATQKIFVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12273-1", "uniprot_id": "PIP_HUMAN", "id": "P12273-1", "name": "Prolactin-inducible protein", "aln": "MRLLQLLFRASPATLLLVLCLQLGANKAQDNTRKIIIKNFDIPKSVRPNDEVTAVLAVQTELKECMVVKTYLISSIPLQG-AFNYKYTACLCDDNPKTFYWDFYTNRTVQIAAVVDVIRELGICPDDAAVIPIKNNRFYTIEILKVE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **::::. . **:*** * : .*: : : :: :. :: :*.*..* *:.:: :**.**. : . :: : : **:***. * .::**: . .. : . .:*: .***:* ::*:.. : : : *.", "identical_positions": 33, "similar_positions": 60, "identity": "22.45%" }, { "cls_id": "homologset.agr.MGI:1934368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U0X8-1", "uniprot_id": "TACT_MOUSE", "id": "Q3U0X8-1", "name": "T-cell surface protein tactile", "aln": "MGRKWTYCVVYTIIQIQFFRGVWEELFNVGDD-VYALPGSDINLTCQTKEKNFLVQMQWSKVTDKNDMIALYHPQYGLYCGQEHACESQVAATETEKGVTNWTLYLRNISSALGGKYECIFTLYPEGIKTTVYNLIVEP-YTQDEHN--YTIEIETNRTLEIPCFQNTSSEIPPRFTFSWLVEK----------------DGVEEVLFTHHHHVNNSTSFKGRIRLGGDYRLHLSPVQIQDDGRTFSCHLTVNPLKAWKMSTTVKVFAKPEILMTVENSTMDVLGERVFTCLLKNVFPKANITWFIDGRFLQGNEEGIYITNEEKNCSSGFWELKSVLTRMHS-GPSQSNNMTAWCMALSPGPRNKMWNTSSQPITVSFDSVIAPTKHLPTVTGSTLGTQPFSDAGVSPTGYLATPSVTIVDENGLTPDATPQTSNSSMTTKDGNYLEASSGTDAKNSSRAAASSKSGSWPFPFTSPPEWHSLPGTSTGPQEPDSPVSWIPSEVHTSAPLDASLAPHD-TIISTTTEFPNVLTTANGTTKIDHGPITSIIVNQPSDGMSWPVLVAALLFFCTLLFGLGVRKWYRYQNEIMERPPPFKPPPPPIKYTYIQEPIGCDLCCHEMEVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BK49-1", "uniprot_id": "TACT_RAT", "id": "Q5BK49-1", "name": "T-cell surface protein tactile", "aln": "MGRKWTYCVVYAIIQIQFFRGAWEELFNAGDNNVYALPGSDVNLTCQTMEKDLMVQMQWSKVTDEIDMIVVYHPQYGFHYMQGVACESRVAAVETLKDATKWTLNLRNISSSLSGKYECSFTMYPTGTKTIVYNLIVEP-YTQDEHN--RTIEIETNRTLEIPCFQNTSSEISPRFTFSWLVEK----------------DGVEDVLFTYDYHVSNSTAFKGRVGLGADYGLRLSPVQIQDDGRTFSCFLRISPLKVWKTSTTVKVFAKPEILMTVENTTMDVLGERVFTCLLKNVFPKASITWLIDGRLFQGNEEGIYITNEEKNSSSGFWELKSVLTRMHN-RTSQSNNMTVWCMALSPGPGNKMWNTSSQPITFSLDSGTAPTKRLPNVTGSTLGAQTFPDAEVSPTRYLATSSMTIVDENVLTPDPTPQTSNSSMTTKDVNYSQPSSGTDAKNSSRAASSSDGGSRPFPSTSPPKWLSLPHTSTGPQEPDSAVSWIPTDAYTSGSSDASLTSHD-VIIRTTKEFPDVLTTANGTTKIKHGHVTGITVNKPRDGMSWPVAVATLLFFCILLFGLGVRKWCQYQKEIMERPPPFKPPPPPIKYMCIQEPTGRGMPCHEMEVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40200-1", "uniprot_id": "TACT_HUMAN", "id": "P40200-1", "name": "T-cell surface protein tactile", "aln": "MEKKWKYCAVYYIIQIHFVKGVWEKTVNTEEN-VYATLGSDVNLTCQTQTVGFFVQMQWSKVTNKIDLIAVYHPQYGFYCAYGRPCESLVTFTETPENGSKWTLHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQTHVTADEWNSNHTIEIEINQTLEIPCFQNSSSKISSEFTYAWSVENSSTDSWVLLSKGIKEDNGTQETLISQNHLISNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKILRSSTTVKVFAKPEIPVIVENNSTDVLVERRFTCLLKNVFPKANITWFIDGSFLHDEKEGIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPVPGNKVWNISSEKITFLLGSEISSTDPPLSVTESTLDTQPSPASSVSPARYPATSSVTLVDVSALRPNTTPQPSNSSMTTRGFNYPWTSSGTDTKKS--------------------------------------VSRIPSETYSSSPSGAGSTLHDNVFTSTARAFSEVPTTANGSTKTNHVHITGIVVNKPKDGMSWPVIVAALLFCCMILFGLGVRKWCQYQKEIMERPPPFKPPPPPIKYTCIQEPNESDLPYHEMETL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**.**.** ****:*.:*.**: .*. :: *** ***:****** .::*********:: *:*.:******:: .*** *: .** :. ::*** ***:*.::.*:*** :.:** * :* :***:::. * ** * ***** *:*********:**:*...**::* **: :*.::.*:: .: :.*** :*.*: ** ** *:****** ****.***.: :.* * : ************ : ***.: *** ** ************.***:*** :::.::*********:: ..** ********:*. .:**:*:* ******* * **:** **: **. :.* :.*. .** ***.:*. . : ***: * **.*:*:** . * *:.***.*******:. ** .*****:*:* ** **::.::*.. .*. : ** .: *: *.:* *****:** .* :*.* **:* ******* **:*** * :********* :**:****************** **** .: ****.*", "identical_positions": 315, "similar_positions": 150, "identity": "50.48%" }, { "cls_id": "homologset.agr.MGI:1934569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZW78-1", "uniprot_id": "D3ZW78_RAT", "id": "D3ZW78-1", "name": "Probable carboxypeptidase X1", "aln": "MCGGFADCAGPGTGEAGFQGPSLRPPGVLGAHQCGPLPGDLTALRSLPSPLLRPRIPASGCGRAGGCRGAWGGGGRGGRKGRGAPQTPAGRKEPTESLGTVRLPILPAMWGLLLAVTAFAPSVGLGLGAPSASVLGLT-------PGSTLAPHSSIAQP------------------------------STKANETSEQHVRLRVIKKKKIVVKKRKKLRQ------------------------------------------------PGPLVTARPLVTTHPAKTPTLP---------------------------EKQEPGCPPLGLESLRVSDSQLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEQQDNEPWLQVDARSPARFSGIVTQGRNSVWRYDWVTSFKVQFSNDSQSWWMSRN-SSGMDMVFPANSDAETPVLNLLPEPQVARFIRLLPQTWFQGGAPCLRAEILACPVSDPNDLFPEAHTLGSSDSLDFRHHNYKAMRKLMKEVNEQCPNITRIYSIGKSHQGLKLYVMEMSDHPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCREFLRGDPRVTRLLTETRIHLLPSMNPDGYETAYHKALSWQGSELVGWAEGRWTHQGIDLNHNFADLNTQLWYAEDDGLVPHTVPNHHLPLPTYYTLPNATVAPETWAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCHSQDFSLHGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHEKELPQEWENNKDALLTYLEQVRMGITGVVRDKDTELGIADAVIAVEGINHDVTTAWGGDYWRLLTPGDYVVTASAEGYHTAKQHCRVTFEEGPVPCNFLLTKTPKQRLLELLAAGAKLPPDLRRKLEWLRGQK------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z100-1", "uniprot_id": "CPXM1_MOUSE", "id": "Q9Z100-1", "name": "Probable carboxypeptidase X1", "aln": "------------------------------------------------------------------------------------------------------------MWGLLLAVTAFAPSVGLGLGAPSASVPGLA-------PGSTLAPHSSVAQP------------------------------STKANETSERHVRLRVIKKKKIVVKKRKKLRH------------------------------------------------PGPLGTARPVVPTHPAKTLTLP---------------------------EKQEPGCPPLGLESLRVSDSQLEASSSQSFGLGAHRGRLNIQSGLEDGDLYDGAWCAEQQDTEPWLQVDAKNPVRFAGIVTQGRNSVWRYDWVTSFKVQFSNDSQTWWKSRN-STGMDIVFPANSDAETPVLNLLPEPQVARFIRLLPQTWFQGGAPCLRAEILACPVSDPNDLFPEAHTLGSSNSLDFRHHNYKAMRKLMKQVNEQCPNITRIYSIGKSHQGLKLYVMEMSDHPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGDPRVTRLLTETRIHLLPSMNPDGYETAYHR-----GSELVGWAEGRWTHQGIDLNHNFADLNTQLWYAEDDGLVPDTVPNHHLPLPTYYTLPNATVAPETWAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCHSQDFSLHGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHEKELPQEWENNKDALLTYLEQVRMGITGVVRDKDTELGIADAVIAVEGINHDVTTAWGGDYWRLLTPGDYVVTASAEGYHTVRQHCQVTFEEGPVPCNFLLTKTPKERLRELLATRGKLPPDLRRKLERLRGQK------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SM3-1", "uniprot_id": "CPXM1_HUMAN", "id": "Q96SM3-1", "name": "Probable carboxypeptidase X1", "aln": "------------------------------------------------------------------------------------------------------------MWGLLLALAAFAPAVGPALGAPRNSVLGLAQPGTTKVPGSTPALHSSPAQPP-----------------------------AETANGTSEQHVRIRVIKKKKVIMKKRKKLTLT----------------------------------------------RPTPLVTAGPLVTPTPAGTLDPA---------------------------EKQETGCPPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHR-----GSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQKD-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PYE2-1", "uniprot_id": "A0A8M9PYE2_DANRE", "id": "A0A8M9PYE2-1", "name": "", "aln": "---MLKQNVHICAAIIVCIARSCFSFENQTVNN---------------------------------------------TVTKTESNDLKSIFN---------------------QTGNVTKSFESAQ-----------------------------------------------------------------RRNSSEDGEQMNKE------SRGAKP---------------------------------------------------------------------------------------------------------DCPPLGLESLKVSDDQLQCSSYLSVGLGPHRGRLNIQSGLEDDDEYDGAWCAGEEDQEQWLQLDSLRLTLFTGVILQGRNSIWSLNWVRTYKVQFSNDSVDWQPCMN--GSQEAVFVGNQDLETPVLALFPEPSVAQFIRINPQTWFSNGTICLRAEVLGCPVADPDSPVDPQTERASLDNLDFRHHNYNEMRKLMKSVSDECPEITRIYTIGRSYTGLKLYVMEISDNPGKHELGEPEFRYVAGMHGNEVLGRELLLNLMQYICHEYKRGNQRIIKLVKDTRIHLLPSMNPDGYETAYEK-----GSELSGWALGRYSFEGIDMNHNFPDLNNIMWDAQDLATDRKRVSNHYIPMPEYYTSTDAMVAPETRAVISWMQDIPFVLSANLHGGELVVTYPFDGTRD-WIPREDTPTADNDFFRWLATVYATTNLVLANPERRMCHSEDFQQHNNIINGANWHTVPGSMNDFSYLHTNCFEITVELSCDKFPHASELPVEWESNKESLLLYMEQVHRGIKGVISDKDTKAGIANAVIKVDGLDHDIRSAVDGDYWRLLNPGDYKITVWAEGYFPRIRHCSVGSEPQATICDFTLTKTSQDRLKQILARGGKLPRDNQVRIRAMRMRKLRASTKILNRRREQQQRLNKVNRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7J9-1", "uniprot_id": "A0ACD6B7J9_DANRE", "id": "A0ACD6B7J9-1", "name": "", "aln": "-MAAAASLLSLLTLTVVLSGGSCRTNSGELISDGETADRLSNTSRSRGVRYTGGALSPSRTSIR--HPGESSTATADYTTSRRRAQEHSRLHNSTHGVKTLTIKPTETSSRALKPTGKTPKPTETSRNTPQPTETSRKPPKPTKTSRKPPKPTKTSRKTPKPTKTSGKPPKPTETSTRALKPAGKPPKLTETSRNTLKPTEASRKTPKSKASSRALKPTGNPPIPTETRRKTPKPTETFSRALKPTGNPFKPTEASIKPLKPTETSGKTSKPSETSRSTVSPSSKPPRTSTVSFSTEDLSESIDKTVEKRVWSSRESTEPPVFECPPLGLESLKVKDSQIQASSYLRRGLGPHRGRLNIQSGVEDGDIYDGGWCAQYEDQQQWLQIHAQKLTRFTAVILQGRSSIWSLDYVESFKVQVSNDTIKWKPCMN--GTQEAVFEGNTDSETPVLALLPEPAVAQYIRINPQSWFKNGTICLRAEIMGCELPDPNNIYPWQSEDGSQDKLDFRHHNYKEMRKLMKSVNEMCPDITRIYSIGKSYMGLKLYVMEISDNPGKHELGEPEFRYVAGMHGNEVLGRELLLNLMQFICQEYKRGNQRILHLVKETRIHLLPAMNPDGYEMAYKK-----GSELAGWALGRYSYEGIDMNHNFADLNTVMWDAIELQTDKSKLINHYFPIPEQYTSEDAWVAPETRAVISWMQTIPFVLSANLHGGELVVTYPFDMTRD-WAPREQTPTADDSFFRWLATVYASTNHVMSNPDRRPCHNEDFLRHNNIINGANWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHASELPTEWQNNKESLLVYMEQVHRGIKGVIRDKDTEAGIPNAIIKVDDIDHHIRSAADGDFWRLLNPGDYDITVTAEGYFPASRSCRVEYEHYPTLCDFRLTKTPKQRLREILAKGGKIPKDLQLRLRQLRTRKLRASTKRINRRHALLQQSRAHH--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : . : * *********:*.*.:::.** ***.**********:**.* ***.*** :* : *:*:.: . *:.:: ***.*:* ::* ::***.***: * . * : ** .* * ***** *:*** **::**: **:*:..*: *****::.* :.**:. .* : ***:****: ******.*.: **:*****:**:*: ********:**:**:*******.**********.******* ***::*:*: **: *: :*:.: ******:******* **.: **** *** **:. :.**:****.***. :* * : : **::*:* ** :* ***** ***.**: ****************:**** ** * .** ***.*: .****:**** :* .: :..** **.:** *.*:****:********************:*********** .*** **:.**::** *:***: ** **: ****: **.:*:* *:.::*.: :* .**:****.**** :*. ****.. : * * * . *:* ****.::** ::** .*:* * : ::. :* :* ", "identical_positions": 347, "similar_positions": 162, "identity": "35.7%" }, { "cls_id": "homologset.agr.MGI:1934582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGZ2-1", "uniprot_id": "A0ABK0LGZ2_RAT", "id": "A0ABK0LGZ2-1", "name": "C-X-C chemokine receptor type 6", "aln": "MFAMDDGHQEKDLDDDVYGGDPWLFNNSSGNSQEHKRFLKFKEVFLPCMYLVVFVLGLLGNSLVLIIYIFYQRLRSLTDVFLLNLPLADLVFVCTLPFWAYAGTYEWVFGTAMCKTLRSMYAMNFYVSMLTLTCITVDRFVVVVQATKAFNRQAKWKIWGQVTCLLIWVVSLLVSLPQIIYSRVGHIDRLICQFHNEAISTVVLVLQMTLGFFLPLLTMILCYSGIIKTLLHARNFQKHKSLKIIFLVVATFLLTQTPFNIAMLIQWISWEYSTITSFQYVVLVTEAIAYLRACLNPVLYAFVGLKFRKNLWKLMKDISCLSRLGVSSQWKSSEDNSKTCSASHNAETTSMFQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ16-1", "uniprot_id": "CXCR6_MOUSE", "id": "Q9EQ16-1", "name": "C-X-C chemokine receptor type 6", "aln": "---MDDGHQESALYDGHYEGDFWLFNNSSDNSQENKRFLKFKEVFLPCVYLVVFVFGLLGNSLVLIIYIFYQKLRTLTDVFLLNLPLADLVFVCTLPFWAYAGTYEWVFGTVMCKTLRGMYTMNFYVSMLTLTCITVDRFIVVVQATKAFNRQAKWKIWGQVICLLIWVVSLLVSLPQIIYGHVQDIDKLICQYHSEEISTMVLVIQMTLGFFLPLLTMILCYSGIIKTLLHARNFQKHKSLKIIFLVVAVFLLTQTPFNLAMLIQSTSWEYYTITSFKYAIVVTEAIAYFRACLNPVLYAFVGLKFRKNVWKLMKDIGCLSHLGVSSQWKSSEDSSKTCSASHNVETTSMFQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00574-1", "uniprot_id": "CXCR6_HUMAN", "id": "O00574-1", "name": "C-X-C chemokine receptor type 6", "aln": "-MAEHDYHEDYGFSS---------FNDSS--QEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLICGYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* *:: : . **:** .:*:: **:*.:*****:****** **:******:* ***::*::******:******************** :***** .***:* .:*::***.*** *********:***:****:*:*** **:* .*****:***********..* .:*:*** :*.* ***:**. **************:*** ******** .****:********:*.***** ***: :*: *** ::***:*.::*******:************.******.***:***.**. **** *******.*** *****.*:******", "identical_positions": 240, "similar_positions": 68, "identity": "67.8%" }, { "cls_id": "homologset.agr.MGI:1934604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIH4-1", "uniprot_id": "LIAS_RAT", "id": "Q5XIH4-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MALR------CWDAARSLGSRIFG----------------------RYACS-VRALSSLP------------------DEKKKFLHNGPDLQDFVSGDLADKSTWDDYKGNLKRQKGE--RLRLPPWLKTKIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDPSEPDNTARAIAEWGLDYVVLTSVDRDDVVDGGAEHIAKTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRANFDQSLRVLKHAKEVQPDVVSKTSIMLGLGETDEQVYATMKALRAADVDCLTLGQYMQPTKRHLKVEEYVTPEKFKYWEEVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRKTKVSKV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M04-1", "uniprot_id": "LIAS_MOUSE", "id": "Q99M04-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MALR------CWDTARSLGSRIFG----------------------RYAFT-VRALSSLP------------------DKKKEFLHNGPDLQDFVSGDLADKSTWDEYKGNLKRQKGE--RLRLPPWLKTKIPMGKNYNKLKNTLRNLSLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDANEPDNTAKAIAEWGLDYVVLTSVDRDDVADGGAEHIAKTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRANFDQSLRVLRHAKEVQPDVVSKTSIMLGLGETDEQVYATLKALRAADVDCLTLGQYMQPTKRHLKVEEYVTPEKFKYWEKVGNELGFLYTASGPLVRSSYKAGEFFLKNLVARRKTKASKV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43766-1", "uniprot_id": "LIAS_HUMAN", "id": "O43766-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MSLR------CGDAARTLGPRVFG----------------------RYFCSPVRPLSSLP------------------DKKKELLQNGPDLQDFVSGDLADRSTWDEYKGNLKRQKGE--RLRLPPWLKTEIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDASEPYNTAKAIAEWGLDYVVLTSVDRDDMPDGGAEHIAKTVSYLKERNPKILVECLTPDFRGDLKAIEKVALSGLDVYAHNVETVPELQSKVRDPRANFDQSLRVLKHAKKVQPDVISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVEEYITPEKFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRKTKDL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PHG4-1", "uniprot_id": "LIAS_DANRE", "id": "Q6PHG4-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MALISR---SCGAASRYSSSHLFLPSKGAEAANVYCN---------RLSTAASTSSSSSPSPST------------HNDRKKDLREDGLNLQDFISGELSEKSKWEEYRGNLKREKGE--RLRLPPWLKTEIPIGKNYNKLKNTLRELNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARRPPPLDPDEPYNTAKAIAAWGLDYVVLTSVDRDDIPDGGAEHFAKTVSNIKERNSKILVECLTPDFRGDLAAVEKIALSGLDVYAHNVETVRELQRHVRDPRANFDQSLSVLRHAKKVKSSVLTKTSIMLGLGETDAQIQATLTELRDSGVDCLTLGQYMQPTKRHLKVEEYVTPEKFAFWEKVGQEMGFIYTASGPLVRSSYKAGEFFLKNLLEKRKTEETTATAE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JQW6-1", "uniprot_id": "LIAS_DROME", "id": "Q7JQW6-1", "name": "Lipoyl synthase, mitochondrial", "aln": "-MLR-------ALKTHAEAPIVVAT---------------------RAASTNAEKLEEIR----------------------ERLAKGPNFHDFVQNPDNTRNEWEQYDGKLRREKGEEQRLRLPPWLKTTIPVGKNYAKIKAQMRELKLSTVCEEARCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARKPPPLDVNEPVNTATAIASWGLDYIVLTSVDRDDLPDGGSEHIAETVREIKARNSNIFVECLVPDFRGNLECVKTIANSGLDVYAHNIETVEKLTPYVRDRRAHYRQTLQVLTEAKRFNPNLITKSSIMLGLGETDEEIENTLKDLREAGVDCVTLGQYMQPTNKHLKVIEYVTPEKFKHWEERGNELGFLYTASGPLVRSSYKAGEFFITSILENRKKRQNDTEVPKKQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32875-1", "uniprot_id": "LIPA_YEAST", "id": "P32875-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MYRRSVGVLFVGRNTRWISSTIRCGTSATRPIRSNALNTDSDNASVRVPVGNSTEVENATSQLTGTSGKRRKGNRKRITEFKDALNLGPSFADFVSGKASKMILDPLEKARQNTEEAK----KLPRWLKVPIPKGTNYHKLKGDVKELGLSTVCEEARCPNIGECWGGKDKSKATATIMLLGDTCTRGCRFCSVKTNRTPSKPDPMEPENTAEAIKRWGLGYVVLTTVDRDDLVDGGANHLAETVRKIKQKAPNTLVETLSGDFRGDLKMVDIMAQCGLDVYAHNLETVESLTPHVRDRRATYRQSLSVLERAKATVPSLITKTSIMLGLGETDEQITQTLKDLRNIQCDVVTFGQYMRPTKRHMKVVEYVKPEKFDYWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRNMK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. : * .. . * .: **:.. .. . ::.: :** ***. ** *.** *:* :::* * ***************** : .. ******:*************** * *. * ** *** ** ***.*:***:*****: ***::*:*:** :* : .: :** * ****:* :. :* .********:*** .* *** ** : *:* ** .** ..:::*:********.* :: *:. ** * :*:****:**.:*:** **:.**** .*:: . *:** * ************** *: .:: .*: . ", "identical_positions": 169, "similar_positions": 86, "identity": "39.49%" }, { "cls_id": "homologset.agr.MGI:1934606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G4M9-1", "uniprot_id": "A0A8I6G4M9_RAT", "id": "A0A8I6G4M9-1", "name": "", "aln": "MEPEDLPWPDELEEEEEEEEEEGKEE-----AENASAAATEEARTSEETGRLEEEELEGAGPEVDLDFNSESQLQESTDEEEDELAKAWLQAHPDRPGQGFSLTPPPTPPP----SSRHQYRPVEHWGKREVRGRAVAWIGAVVIPLTYRAWQQTSYQDNARAQFSNSSTLLLEPEFQWDPEEVQRTESWHHLPQERDSFQTLNISQTGID-RVEGAEVKDLPSQEGGESVQAQCPVKEPKLDLLCSPLLVIQDDFAAPDLPLLTCMTQDQE-FEPDSLFQQSELEFAPLRGIPDKSEDIEWLARPSEVSEALIQATSESSSDLVNSCFSISQHPLTGSTIFGSQRSLSLFEQENNRETVPCNAPDDLKSPDNSYHYDAQYSYMSWLTEKDTQQPEGSLADKDQASSTTISDISDESITVKRSSALGISCSYSQYRKQEALKQTEASLASKDHASFSRQITSLPNKMSRSFLRCMLKRGEGTPLTSDNP------------PENVCLRTPAEDEMSQKNDSLEGYEGNEDLQKELSQYFKQKETRNTWASSRVHAKYPEIKSLGTVAIPESQKRVAESYILCRGLDISKLDTSGCPLPTVKSNFNETSEQLCFQEERNQKAATTFDEKNVDATGNVAFEAIIASIESSNQEGSVSETQTDSSQLLADDSEEKKTLKPDLSPFSCKDEISFIDKLKYQYQSTPAVFEPADSKPLLCKEDDAGSLYHYPDLKHPINVPQSMLEGLQGKAKSDVLILFGDAKYASIYENAGAHSERITELQREVDCSN------LSITQAFPS-SLP---------------SFVPQE-----------------PTIESEYHSSNLRMLRVSPDTLLTTLT--------QTTGSVDQKIGAAAISS--------------------------------------------------------------------------------------------------------------------------------------------------PYSHGVQPGSFPQEELPDRHLTEEIRKVSPAPRPAGQKPEMPTVPSSSYSKGIK-SVFYRYPMSYSPQGKEPPNVSSVSGSAENALPLTVTSVSQPQRETAKAFYQQ-TLSDSLLTAETLPVSVIPESGDQKTHLLSGFSLSYSHR------------------------------------------------------------GEDLPEDVVKVSTDSGSVDKKADIPTVSSSTYQHKTKPGIIYYQEFPDSH-------VPIGTRKVVSQSGAAG-----------------------------------------QKTDLSAVPSTSSSQAEKPVPPSLLTLLGSHLPEDVFKASYVCKSSEEPSGITALTSVSYSYKG-RPNISHQEKFPDSYLIEEAQKILGSTVTVDQKTVT---------AKEKPSVFYQQALPEGGLSAEDLQV-------DQNIAIPMVTSASFSQREKPQVFYQEALSGGHLPGEPP------------------------------------------------------GPPDQNTEAPTISPSSYFPGEESIIFYQAGFPGNTPSVVPFKVSRISELAEQKTNITTGPSGSYSVGEKSIIFYHQALPDGHLSKEAS-----PAPADLKTGEPPVYSASCSVEVKPIIFYQQPLSDSPL-TKGHNVSVVPGPTDQKTGIPAVPSTSQSYIERRSVSYQQEFPN--VSEKALKVLGGVRSTEQKTEIPVVSSALL-HTEVPTISSQEDLPN--LTEEALQIL----------GVAEEVPSVPSRDKTRLISYQKKLPDGTEVSLKSVGF-GSTDQKTGAHIVSSSRR---EKSSGFHQQELPNTCGDALGTF-HPEPVAQKVGKPTEPSN-IQGKASALSPQQLPASHLTGEALKVSDGSACVAQMPEAPAGPSIFYFHKERFSNY-QKASPDCDLTENSLKSSTVPGLSDQKKRPPV---SSGSCSHKEKHKISAADLLDAQAAELPTVIQRSCLHREKLAISTVIKPDDPKIPLPTTCHASCAQKVKPVIFVQKQLSGRDQSEDIPKISTVSEPTVANTGAPVLLSSSYPYREKSDFSSPKELP-----------------------------------------------DRHPAKVDMQASSSLGQADQISRLPTVPPGTYSHSEKYQLISEHVQELIDNLNSSESCLNADIMMPSNSQIDDGVIICKPESSRFANVGCEEIQDIDHGSKTLKEIQTLLMEAENMALKRCNFSVPLVPFRDVSDVSFVQSKKVVCFKETPTSDVCIQ----KDSFAEEVPHTKYVQKDIGTQTNLKYQRNVRNWEFISSATFRSPLHEANGTARVAFDENFRQYRATRSVMRSEPEDCSTGIGDKIIIPMMTIIKSDSSSDVSDG--CCSWDNNLPESLESVSDVFLNFFPYTSPKTSITDSREEEGLSESEDGYG-SADSLAAHVKYLLQCESSLNQAKQILKNAEEEEYRVRAQAWNLKFNLGRDYGYPVSELNEDDRRKVEEIKAKLFGHGRTTHVSEVLQSPRGIGCLPEAVCGHIIIESHEKGCYRTLTAEQPRPDSCHCVFRSVDPSDLIRGHRSPSSWRGRHINLSRSIDQSNPHFKIGNSFQLQSHPPFEKLVPDDIKISKGVGMPFHEHMDPQPSELIEPTCVPAKEMDFSSSSEILPSEPKKQFTTSITFSSHQHSKCISDSSGFKVDVTAGSQCTGPSLGVFKPHIPEEQISPRDLKQKISSPSSLQRHSYTP---VTILVDSSRQRQKLPVDFEHSNQKGKLLQRSAFNFSHSEPSVSTNVS-FKGVQFSGNDTIVRQ---------DKLISTVEVKEKNVTLTPDLPSCIFLEQG---EESHTPHTDLHMRKCPSPS-------GLDIASCIFLEQHKFFEQSQGQHVDDHEMREDYSLFPKCQGYIAADPS-DFPDQQ-QCKPPGVDGHVRKQHYPLSPVQDCEVEEVQCIPQSYFSNMVNVEAKVSDMVSPDAPDHFTAAS---TPPSSRKALSCVRITLCPKTPSKLDSGTLDERFHSLDPASKTRINSEFNSDLRIISSRSLEPTSKLLTCKPVAQDQESLVFLGPKSPLDLQVAESSLPDSKTISQDLKTTPPQNSQIVTSRQTQVNISDLEEYSKPEGTPVPADGSQEQNKAPFTTSSGMLSSDAVTQVTTESPEKMTFSSEIFINADDRGQDIPYPTTQ----NPSRFASSSSGQQITASQGKDAQPVLLPYKPSGSSKMYYVPLLKPVPSYLDSKSDTTVESSHSGSNDAIAPDFPPQVLGTRDDDLSTTVNIKHKEGIYSKRAASK-----GKQPSQK---EAPVQMPVTWDKNVYKENQDEIISRRVVIETAGPEEMPSQEKDLAGSS-------DITVQDRKTGNLPDAKSIKQKE-----------------GSLEI---EPECHSEFANTTHSVFRSASFYFHHPVHLPQEQDLCRESSGRNVLTQHPWKDLFHCHSG----HSGLPPPGPRS---DNTEMECTRVKSLSMDLNLGGHEKIHTIKNQARDTKEDKRPANDPKKDQKVTPELTSQCPMSLNELWNKYQERQKQQKPSGACDNKELSLVERLDRLAKLLQNPITHSLQASESTQDDRRWGRGARGWTGRRQHQQKGKQQRKWSKSLERGHS-TGDFRKSKVLSPHEGGKSSQRNIEKIKLDKYILRKQPDFNNVSNTSLDSRPSEESELLLTDSPNLFSSTESPVESDVLTHTGRDMPLNERSSSISTVDTARLIQAFGHDRLYLSPRQIKLYSSVTNQRRKHLEKPCKHKRKALNTACPQMTSEHTRRRHVQVANRIMSSDSVSS-AGSCLSLDSTLSNEENVHMLNKGVQAGNLEIVT-GAKKYTQDVGVTFPTP-----SSSEARLEEDSDMTSWSEEKAKEKKFLSNYLRGKNLRKNKPNPCEGVSWFVPVENRKSESKKENLPKIYRP---AISWFEPVTQTKPWREPLRE--QNWQAQCMNSRGSLGGPGRDSGQ-SFLQPFVRATLQESLQLHRPDFISRSGERIKRLKLLVQERKLQNLFQNEREALFNTAR----------PLPRRVLLAVQ-----------KNKPIGKTEMIRRTRRFYEQLPEVKKKREEEKRKSEYTSYRLRAQHYKMKVTNHLLGRKVPWD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4E0-1", "uniprot_id": "ALMS1_MOUSE", "id": "Q8K4E0-1", "name": "Centrosome-associated protein ALMS1", "aln": "MEPEDLPWPDELEEEEEEEEEEGEEEEGKKEVENASAAATEEALTSEESGRLEEFEEAGP----DLDFNYESQRQESSDEEEDELAKAWLQAHPDRPGSAFSLPPPTPPPPPPPLSPRLRYTPVEHLGKTEV------------VPLTCRVWQQSSYQDNSRAQFSNSSTMLLETGVRWGSEEDQRTESWHCLPQERDSSQTLAMSQTEIG-RVEGTEVPDLPSQEGGLPAQSQCPGKKPKLNVLCSPLLVIQDNFAAPDLPLLTCLIQDQEEVEPDSLFQQSELEFAPLRGIPDKSEDSEWLARPSEVSEALIQATSETSSDLANSCFSISQHPLT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGLQGKAESGVLTRCGDAKYSSLYENLGAQSERIAVLQREVGCSN------LGISQASPS-SLP---------------SFVPQE-----------------PTSEPEYHSSNLRMLRVSPDTLLTTHT--------HSAGSADQKIGAAVVSS--------------------------------------------------------------------------------------------------------------------------------------------------AYSQEIKPGSFHQEELPDRHLNEEIRKVSPALRTAGQKPEMLPVQSSSYSKGMK-SIFYQHPVSHGHQGKEPLSVSAVCGSAGN-----------------KAFHQLSTLSDSLLTEETWPVSVIPGLGNQKTPLPSEFSLSYSHR------------------------------------------------------------GKNLPEDVVKVSTDSGSAHKKADILTASSRTYQHKMKPANIYHQELPDSR-------VPIGTRKVAFESGPAGQKSGVSHPYGEMPSVFYQQGLPDRHSAKSPT-KTFIPGPADQKTDLSPVPPTSSSHAEKPVSPYQLTLPGSHLPEDVFKASSVCKSSDELSGITALTSASYSYKG-RPNSSYQQKFPDSHLNEEAQKILGTTGTVDQKTVTPTMSSSFL-QKEKPSIFYQQTLPDGGLSEEDLQVSAVPWPADQNIAIPTVTSAAFSQREKPRIFYQQTLSVDRLPGEPLNVLGTS------------------------------------------------GPPDQNTGAPTVTPSSYFPGEESIIFYQAGFPGNTLSAMSFKVPRISGSTEQ-TNVTTGSSSSYSVGEKSIIFYHQALPDGRLPQEAS-----PAPADLNTGEPPMYLASCSVGVKPIIFYQQPMSDSQR-TKGHKESDVPGPTDQKTGIATVHSTSQSYIGRRTVSYQKEFPD--LSEKALKVLGDVGSTEQKTQIPVVSSALL-HKEGPSAY-QEDLPD--LTEEPLQIL----------GVSEEVSSS---------SYQRKLPDHIEVFLKSVGS-GSADRKTGAQIVSSSR----EKSSGFHQQELPNTGGDAVDAF-HPEPVVQEVRK---------------------------------------VQTPGAPAGPSSSHFHKEKLSDY-QKASPHRDLTESSLKASTVPGLSDQKKKPAV---SSGFCLHKEKHEISASALLNCQTAELLTVTQRSCLHREDPAISTVIKPDDQKIPLPTTFHGSSDQKVKPVIFVQKQLRDRDQSEDIPKISTVSEPTVVNTVLPVLLPGSYSHREKSDSFYPQELP-----------------------------------------------DGHLTEVDLKVSSGLGQADQISGLPTGIPGTYSHSEKHQLISEHVQELMDNLNSSESSCLSVDSMPLNSQIDDGVIICKPESLGFANAGCEEMQNIDRGSKTLKEIQTLLMEAENMALKRCNFSVPLVPFRDVNDVSFIRSKKVVCFKESSTTDVCTQ----RESFVEEVPHIEYVQKDIGTQTNLKYQRGVGNWEFISSATFRSPLQEAEGTARMAYDETFRQYKAARSVMRSEPEGCSTGIGNKMIIPMMTIIKSDSSSDVSDG--CCSWDNNLPESLESVSDVFLNFFPYTSPKTSITDSREEEWLSESEDGYG-STDSLAAHVKYLLQCETSLNQAKQILKNAEEEEYRVRTQAWNLKFNLGRDRGYSISELNEDDRRKVEEIKAKLFGHGRATHMSEGLRSPQGIGCLPEAVCSRIIIESHEKGCFRTLTAEQPRPDSCHCAFRSVEPSDLIRGHRSPSSWRGRHINLSRSIEQSNPCFKVGSSFQLQSHPPFQKLLPDDIKISKGVGMPVHAYMDPQPSELVEPTCVPAKEMDFPSSSQILPPEPKKQFTTAITFSSHEHSECISDSSGCKVGVTADSQCSGPSLGVFKPHIPEEQISPRDLKQKTSFQSSLERHGSTP---VTILADGSRQRQKLPVDFEHSHQKEKLLQRLGFKVSHSEPNVSTNVSNFKGVQFSGKDTIVSQ---------DKLTSTVEVKEKNVTVTPDLPSCIFLEQPELFEESHTPHTDLQMRKYPSPS-------CPEIASRIFLEQPKLSEQSKAPHVDR-EIREDHSFFPKCQDYIVADPSPDFPDQQ-QCKPPDVVGHTRKQNSLLSEGQDYELEEVQHIPQSYFSNMVNVEAKVSDAISQSAPDHCTAAS---TPPSNRKALSCVRITLCPKTSSKLDSGTLGERFHSLDPASKTRINSEFNSDLRIISSRSLEPTSKLLTCKPVAQDQESLVFLGPKSPLDLQVAQSSLPDSKTIFQDLKTKPPQNSQIVTSRQTQVNISHLEGYSKPEGTPVSADGSQEQSKVSFTTSFGKLSSDAITQITTESPEKTTFSSEIFIHADDRGQGILDPMAQ----KPSRFASSSSVQQIPASHGKDAQPVLLPYKPSGSSKMYYVPLLKRVPSYLDSKSDTTVESSHSGSNDAIAPDFPPQMLGTRDDDLSNTVNIKHKEGIYSKRAATK-----GKNPSQKGDAAAPVQMPITWDENVLDENQEEVISRGVVIKMAGPEEMSSLEKDLAGPS-------DITVQDRKTENLPDTKSIKQKE-----------------GSLEI---ESECHSAFENTAHSVFRSAKFYFHHPVHLPHEQDFCHESLGRSVFMQHSWKDFFHHHSG----HSCLPPPGPSSDKLDKTKMDYTRIKSLSINLNLGEHEKIHTIKNQARDPK-GKRQANEQKKDQKVTPELTTECPVSLNELWNRYQERQKQQNPSGACDTKELSLVERLDRLAKLLQNPITHSLRASESAQDDSRGGHRAREWTGRRQQKQKGKQHRKWSKSLERGQS-TGDFRKSKVFSPHQGGKSSQFKIEQIKLDKYILRKEPGFNNVSNTSLDSRPSEES-VSLTDSPNIFSSTDSPVDSDVLTPTDRDMPLNERSSSISTIDTVRLIQAFGQDRLSLSPRRIKLYSTVTSQRRRYLEQPCKHNRKALNTACPQMTSEHSRRRHIQVANHMTSSDSVSS-PGSLLSLDSALSNEETVRMVSKGVQAGNLEIVA-GVKKYTQDVGVTFPTP-----SSSEARLEEDSDVTSSSEEKAKEKKFLSNYLQTKNLRKNKPNPCAGVSWFVPVESGQSGSKKENLPKIYRP---VISWFEPVTKTKPWREPLRE--QNWQAQCMNSRGSLGGPGRDSGQ-VSLRPFVRATLQESLQLHRPDFISHSGERIKRLKLLVQERKLQSLFQSEREALFHSAR----------PLPRRVLLAVQ-----------KNKPIGKKEMIQRTRRIYEQLPEVKKKREEEKRKSEYKSYWLRAQHYKMKVTNHLLGRKVPWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCU4-1", "uniprot_id": "ALMS1_HUMAN", "id": "Q8TCU4-1", "name": "Centrosome-associated protein ALMS1", "aln": "MEPEDLPWPGELEEEEEEEEEEEEEE--------EEAAAAAAANVDDVVVVEEVEEEAGR--ELDSDSHYGPQHLESIDDEEDEEAKAWLQAHPGR------ILPPLSPPQ-------HRYSEGERTSLEKI------------VPLTCHVWQQIVYQGNSRTQISDTNVVCLETTAQRGSGDDQKTESWHCLPQEMDSSQTLDTSQTRFNVRTEDTEVTDFPSLEEGILTQSENQVKEPNRDLFCSPLLVIQDSFASPDLPLLTCLTQDQE-FAPDSLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHPLIGSTAVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDRYDDLCSYMSWKTRKDTQWPENNLADKDQVSVATSFDITDENIATKRSDHFDAARSYGQYWTQEDSSKQAETYLTKGLQGKVESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSS-SYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVSEHVQRLIDNLNSSDSSVSSNNVL-LNSQADDRVVINKPESAGFRDVGSEEIQDAENSAKTLKEIRTLLMEAENMALKRCNFPAPLARFRDISDISFIQSKKVVCFKEPSSTGVSNGDLLHRQPFTEESPSSRCIQKDIGTQTNLKCRRGIENWEFISSTTVRSPLQEAESKVSMALEETLRQYQAAKSVMRSEPEGCSGTIGNKIIIPMMTVIKSDSSSDASDGNGSCSWDSNLPESLESVSDVLLNFFPYVSPKTSITDSREEEGVSESEDGGGSSVDSLAAHVKNLLQCESSLNHAKEILRNAEEEESRVRAHAWNMKFNLAHDCGYSISELNEDDRRKVEEIKAELFGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTSEHPQLDRHPCAFRSAGPSEMTRGRQNPSSCRAKHVNLSASLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFKISKGLRMPFDEKMDPWLSELVEPAFVPPKEVDFHSSSQMPSPEPMKKFTTSITFSSHRHSKCISNSSVVKVGVTEGSQCTGASVGVFNSHFTEEQNPPRDLKQKTSSPSSFKMHSNSQDKEVTILAEGRRQSQKLPVDFERSFQEEKPLERSDFTGSHSEPSTRANCSNFKEIQISDNHTLISMGRPSSTLGVNRSSSRLGVKEKNVTITPDLPSCIFLEQRELFEQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFLEQRELFEQCKAPYVDH-QMRENHSPLPQGQDSIASDLPSPISLEQCQSKAPGVDDQMNKHHFPLPQGQDCVVEKNNQHKPKSHISNINVEAKFNTVVSQSAPNHCTLAASASTPPSNRKALSCVHITLCPKTSSKLDSGTLDERFHSLDAASKARMNSEFNFDLHTVSSRSLEPTSKLLTSKPVAQDQESLGFLGPKSSLDFQVVQPSLPDSNTITQDLKTIPSQNSQIVTSRQIQVNISDFEGHSNPEGTPVFADRLPEKMKTPLSAFSEKLSSDAVTQITTESPEKTLFSSEIFINAEDRGHEIIEPGNQKLRKAPVKFASSSSVQQVTFSRGTDGQPLLLPYKPSGSTKMYYVPQLRQIPPSPDSKSDTTVESSHSGSNDAIAPDFPAQVLGTRDDDLSATVNIKHKEGIYSKRVVTKASLPVGEKPLQNENADASVQVLITGDENLSDKKQQEIHSTRAVTEAAQAKEKESLQKDTADSSAAAAAEHSAQVGDPEMKNLPDTKAITQKEEIHRKKTVPEEAWPNNKESLQINIEESECHSEFENTTRSVFRSAKFYIHHPVHLPSDQDICHESLGKSVFMRHSWKDFFQHHPDKHREHMCLPLPYQNM---DKTKTDYTRIKSLSINVNLGNKEVMDTTKSQVRDYPKHNGQISDPQRDQKVTPEQTTQHTVSLNELWNKYRERQRQQRQPELGDRKELSLVDRLDRLAKILQNPITHSLQVSESTHDDSRGERSVKEWSGRQQQRNK-LQKKKRFKSLEKSHKNTGELKKSKVLSHHRAGRSNQIKIEQIKFDKYILSKQPGFNYISNTSSDCRPSEESELLTDTTTNILSGTTSTVESDILTQTDREVALHERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKRSKHSKKVLNTGHPLVTSEHTRRRHIQVANHVISSDSISSSASSFLSSNSTFCNKQNVHMLNKGIQAGNLEIVN-GAKKHTRDVGITFPTP-----SSSEAKLEENSDVTSWSEEKREEKMLFTGYPEDRKLKKNKKNSHEGVSWFVPVENVESRSKKENVPNTCGP---GISWFEPITKTRPWREPLRE--QNCQGQHLDGRGYLAGPGREAGR-DLLRPFVRATLQESLQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDALFNIDRERQGHQNRMCPLPKRVFLAIQ-----------KNKPISKKEMIQRSKRIYEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQLLGRKVPWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H474-1", "uniprot_id": "A0AC58H474_DANRE", "id": "A0AC58H474-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MDSVGDAADVNNTPAETPCQKHGQNIHDSEVDRPYAG---------------------------PANDGRPFNNLQDSSIQPMMNRFEILQLEFQDSQLSPALPLLPCLD-KSNFLSNSSVFQETDLEFVPLRGIPDFSVIPERCSSISDEAVTVDSQLQTSIHDQAT----ISEHPLEVPTALS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGENSSCSLSQHSLSHNDHSRGLGNQSSVLYSNEYKINRHMEGEE------QTAAQRLSEG-------------------------------------------------MHARPLLELREEDISVAVS------------------NSSAISS------------------------------------------------------------------------------------------------------------------------------------------------------PSEPGSNHQN----------TQKIQTSPSNLQADREQPQGGSLSLTSSFQKATVSTARSDVSN------------------------------------ITFRDSQMDTHQTADHLHDQLLTASG----------------------------------------------------------------------------------SLSAPASRLHGGNKSSDSAQSFTIAGEDLIHVPGLQRALLSSGGR----------------------------------------------------------------------LIGADGSFLSSQPVFQSTPAVPPTRPLPALTKPSLIHSKQKAVASAATLPQSNQSRTGLMPLLDLSDQHSSSMYSQTTSSKP---------------------PKTEQTVSHAHSVSNEHISPAVLNP-----------------TAADTSRSDTQLFYSSTEKKDQVS---------------------------------------------------------------HLALGRVQSLPSLSYLQKVDAWKANQSSSRSFCDNLALQGVDGVSLKKKAQDVGSDIFNQMDSR-----------------------------------DKHQALCMNASSQSIQQLSSSHSGSVSPRRVDEAGASVCKGQASDSPVIRSQSHSS----------------LSSVVTSIQRDTGTLSKQAPLTQ---------------------------------------------------------------SKDVPATNQSSLISGGS-----------------------------NEGMNTSAAHMDTN----------------------------------------------------------AIKMSPFLSLGRFSDVSSSVN-----LSSTLSSSQGSYHGEQSMRASVG-------AASSVVSLEVDNYAPYWTSRPTSPPHTREFNIEDRIPLYLLNLGIDQSPSTILNPFTRRGPIREPEFSPTDLCTIKGSIGTPTKSTQ--PSEVDSLQKETFSSSSQHSTESSASVSHHLS-----------------------------------------------------------------------------VHELSQPATDSSVKVILTQADAAQLQSTSHPSTTLQQSDAAESERSFSLPVPESGPREVVKADDDSLVGSGTLHEIRRLLGRAESLVSGRSSLTSSPGSHRLSESDTSLVSLGRNARGYHTDTSLSAG--------GNLSLLLTRSSSDSALKGSLSSSQGPQHIDLTT---------VKPAALSLSREESLKARDLRVTPRRAEPEGCSAADPDKGKPTTTTSGTQINLPSIAVS---------VPQNEEDTSEDAP---IGSSENSLSHVSAEAESLSDSS-----SESSLAARVAKLLQSESPVSMVTSRPSTADPEDS--RAREWILMKVSGRRCES--LELNTEDRKRIEEIKRELLLNTKYTKWSSDSEG---------SAQSSIGLESQQTKGYVGLRN-------------------------------------------------------------------------------MENRLSDQLQKAPSNPLSTVQDLEAKVHEIALREGFSTKPFTSITISTTRRTPSPQSPPHSPVTGTLKITNVG-------------------------------------------------SANETPAGTKDSDRE--------------------------------------------------------------------------------------------------------------------------KETEGQHIDEKKTTEDK-----------------------------------------------------------------QENTITDKAQRMSHIDYNVTS---STFNNKSHLSHIHVTLSPK----------------------------------------------------------------PKNQIRFEKSTQNISQDVALQRPIVPSVADPQLEPMHRISTLNHVSSYEYR------------------------ERVQGQNTGRVSARFPARHTQSSAPSNRLDMKSRTLSG----------------------QTAYGTAAVPTLLPYKPHGSSELFYMPQVDPELS--PGRSDTTVESSHPDSDDAVPPHFNKDILGSREQED-NTITPKHKEGIYSKRTNMN----------------------------------------KVSSGDCPPKSASTFVSTAPEVS------------KKNMETVGIDAEYNDKE------------------------------------------------DHFVPLNMEADNS--------------------------------------------------MDHVHFHNSTTQEPKIPREPHYSSSQPNRRPYRGNKKGKDRTPHDVSLEITSSLDQLWRRFNEKWSTEESRSINDG-ETSLLDRLERLSRLIHNTTPTDHSVQQSSD--------------------------------------SGNGEYDRMRNQEEEEQRERVQLKAPPKHAWVQDEGQGKVHLCPAERDES-------------------------------------VETSSSVSTVDTERLQRAFGAHRVAREG--MKSDGSLLRLYNSINAKKTSRRKPSTKDAAVSVTTDNTDDSTVSAGSLSSSSTSFHHSQRGVYSLKTKKSK---VKLVSKSVQAGDLEIVINGTRKHTRDVGTVFPSPGAFKNVSSSNKFGSGLQNGIPIPTASTAKPIQTALKRDSSNKSVRTRYPHGVSWFVSADELKFDGRKENQPQNESEPSISQAWFEPYSRTRPWRESSREPLRERQNQQEQERQTETRTAMETDISDKTSALVRLSLQEALELHRPEFVSRSRERMKRLGLLVEERRLQAIFNREREELFNFPAPSR--PLRAAPVPRKRVVPRKEMVQRSRDWVGKKSHSQRIDRTDRLRRKYAKLPEVQKRREEEKRRAEYRSYRLTAQLFNKKVTNRVLGRRAPWQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :: . *. : : : :* : . *: : : : :* : : * :**. :* ****.*: ..: . .*:*::::*.*.******* * * : *: : :: . * .. :*:*** : ... : : :: . . .: . .. :* . : : : .:..::* :*. *: *:... . * * * .. : : . . . : : :: . : .: . . . .* * ... . : : . *. ...: : . :.:* .: :: * * . . :. .::.. . * * .:. ..* : :.. . : : : :.. :. *: :.: : ... ::*..: .::. : . . : : :: ... : : :. : : . .*. :..: : : . * .. .. . . . .. * : . : * * ::. . .: . .::: :. .:.:* : * :* : : : : . : * .. ..:*. * . .:*. .: .. .:.. :. : : *. :: . : * : :: : :* . * . . *: : .:: :..* : :*. .:.*. .:. .: * :* : . :* . : .. :. : * . : :: .: **:**: ** .**.:. *..:. . .* .. : : * . . :.:. : ..* . : .*. :. : :: : . :: :*.:: : *:***.** :* . * .. . .. : . :*:. *..*: * :: * * * :*:*. * .****:* ***.*:.:. ... .*: *: *:: * : .: *** :**:::**** :*: : : *. *. .. :. . * :**::. : * .. :. .: . . . :::: . .: *:**:*: .:: . .... * * * . :: *.. : * :: :: :. ::* : *: * ... . : . . :: :. ..:. ** :::**.** **. : :: .:.:. :: : : . .: . * :* : :..: ::::. * : ** . : :.: : : *. . * ****** **::::*:* : . .:*********..*:**:.*.* ::**:*::: *:. **********. : . . .:. : . . * . : .: .:** .* * * : * . :. : :. . . : . . .: : .::.. : : : . **::**.::.*: :. * * **::**:**:::::*. . . ..:*:. :*: . .:: . .. : .: ::: . :: : . :. :. * * ***:**:** ** :*** .*: . :* .:: . : .: : : . :*:::: :.... ** *. . * .: .: *:::.*.:***:**** *.:*:*:*** .**:* **. :: .. : * : : . . :. : . ******..:. : .:*** *: :**** ::*:****. ** :: * * : * .. ::. .:** :***:*::***:*:*:* **:*** *:*:**:** ::: **: **: *:*:: .:. : *:. : : * :* * :****:*:******::** ** * ** :: :***::***:.**:", "identical_positions": 349, "similar_positions": 741, "identity": "8.24%" }, { "cls_id": "homologset.agr.MGI:1934659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWZ0-1", "uniprot_id": "A0ABK0LWZ0_RAT", "id": "A0ABK0LWZ0-1", "name": "", "aln": "MVMISAVNLVILLSLLCEARTIVLLNFTDSS-LPANNFSDI-EATLSVPVLSVDIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPS---YLLRF-LGQNLSVRTG------RYRSILQLVKP----WYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCS-------------SCPPSYGGACTDNLCFPGAFCIFCVGEDI--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BS03-1", "uniprot_id": "PI15_MOUSE", "id": "Q8BS03-1", "name": "Peptidase inhibitor 15", "aln": "MIMNSAVSLVILLSLLCEAHTVVLLNPTDSS-LPANNFTDT-EAALSTPLESADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPS---YLLRF-LGQNLSVRTG------RYRSILQLVKP----WYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCS-------------SCPPSYGGACTDNLCFPGVTTNYLYWFK---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43692-1", "uniprot_id": "PI15_HUMAN", "id": "O43692-1", "name": "Peptidase inhibitor 15", "aln": "MIAISAVSSALLFSLLCEASTVVLLNSTDSS-PPTNNFTDI-EAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPS---YLLRF-LGQNLSVRTG------RYRSILQLVKP----WYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCS-------------SCPPSYGGSCTDNLCFPGVTSNYLYWFK---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T141-1", "uniprot_id": "PI15A_DANRE", "id": "Q7T141-1", "name": "Peptidase inhibitor 15-A", "aln": "MNENRLAIDILLLCISCGASALAGFSPTASSSLPATNLTDIGFAPPKYLTEAANIPKTRRKRYISQNDMLAILDYHNKVRGKVFPPASNMEYMVWDDTLAKTAEQWASTCIWEHGPR---NLLRF-LGQNLSVRTG------RYRSILQLVKP----WHDEVKDYSFPYPRDCNPRCPLKCYGPMCTHYTQMVWATSNKVGCAINTCHNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCS-------------MCPPSYGGSCSNNMCFPAVNSNYLHWFK---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A286Y9K7-1", "uniprot_id": "A0A286Y9K7_DANRE", "id": "A0A286Y9K7-1", "name": "", "aln": "MKTVNFFTDLLLVFIASDASAWVIRNATETQ--TGTNLTFS-TSELGDDQGIGSKPKSRRKRYISQSDMIAILDYHNKVRANVFPPAANMEYMLWDDGLARSAEAWAATCIWEHGPP---YLLRY-LGQNLSVRTG------NYRSILQLVKP----WYDEVRDYMFPYPRDCNPHCPMRCYGPMCTHYTQMVWASSNRVGCAIQTCFNMVVWGAVWREATYLVCNYSPKGNWIGEAPYRVGVPCS-------------ACPPSYGGSCSNNMCFPAINSNFMYWFK---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRL3-1", "uniprot_id": "Q8IRL3_DROME", "id": "Q8IRL3-1", "name": "Venom allergen-1", "aln": "-MSRSPCWIFLLYLVLIIFTFTFAQNYCDPELCPSGRHVACQNSGRFVSGCSGEFVQVDAHIPLILQLHNERRNLIAGGGVSGFPSAVQMATMSWDTTLAQLAAYNALQCRMAHDECRNTNTYRY-AGQNLSILFT------RSVDVAVFLRQRIAAWFDENRDATSGDMEDYQMRG-----GPAIGHFTTMVNERNNRVGCAIARFTDANN-----VQATLLACNYAVT-NVVNNPVYRAGTAAS-------------ECTTGRNSNYPN-LCSPNEVYNYNQWSG---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFY2-1", "uniprot_id": "Q9VFY2_DROME", "id": "Q9VFY2-1", "name": "SCP domain-containing protein", "aln": "MMQPSAVLLTTIMIISCEVAFACNGKIIASG-------------------------ITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHR--TINRFTMGQNLAIIWSTAPLDADDGDFPSRIQS----WFNEVQKYSFGD-----------AWSPKTGHYSQLVWGETSLVGCGYAEYKDTSKYN------KLYVCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSSRYQGLCAAPGSSPAANSVYGANTIETYEYGYNSSPSSQTANNNPPTNNINKSQFSYNQPRPKPVQTINPNPSPFNPQAAVPSASTFGGSSFGSASRGGSHAYTTDPSQSAGRYKHKLEAYRPSAAEFEKSVHKHTILRTYIEQNQQRQDQQQQQQQKEQDQQQQQPEPSSTKKPSRGWSLLTWRG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : . : * * :* : ** ** * * * *. *: ****:: .. :: *.:* :. .* *:: :* .. :**. : .***. * :. *..* ... *.. .. .: : . : ", "identical_positions": 30, "similar_positions": 49, "identity": "6.82%" }, { "cls_id": "homologset.agr.MGI:1934666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGD2-1", "uniprot_id": "CRLD1_MOUSE", "id": "Q8CGD2-1", "name": "Cysteine-rich secretory protein LCCL domain-containing 1", "aln": "MMC-KAQEWLRVTALLFVARAVPAMVVPNATLLEKLLEKYMDEDGEWWTAKQRGKRAITDNDMQSILDLHNKLRSQVYPTASNMEYMTWDVELERSAESWAEMCLWEHGPASLLP--SIGQNLGAHWGRYRPPTFHVQAWYDEVRDFSYPYENECDPYCPFRCSGPVCTHYTQVVWATSSRIGCAVNLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHGRPCSACPPSFGGGCRENLCYKE-GSDRYYTPREEETNEIERQQS--QVHDTHVRTRSDDSD------RNDVISTQQMSQIVSCEVRLRDQCKGTTCNRYECPAGCLDSKAKVIGSVHYEMQSSICRAAIHYGIIDNEGGWVDVTRQGRKHYFIKSNRNGIQTIGKYHSANSFTVSKVTVQAVTCETTVEQLCPFHKPASHCPRVYCPRNCMQSNPHYARVIGTRIYSDLSSICRAAVHAGVVR-NHGGYVDVMPVDKRKMYTASFQNGIFSESLQNPTGGKAFRVFAVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFM5-1", "uniprot_id": "B5DFM5_RAT", "id": "B5DFM5-1", "name": "", "aln": "MMC-KAQEWLRMTALLFVARAVPAMVVPNATLLEKLLEKYMDEDDEWWTAKQRGKRAITDNDMQSILDLHNKLRSQVYPAASNMEYMTWDVELERSAESWAETCLWEHGPTSLLP--SIGQNLGAHWGRYRPPTFHVQAWYDEVRDFSYPYEHECDPYCPFRCSGPVCTHYTQVVWATSSRIGCAINLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHGKPCSACPPSFGGGCRENLCYKE-GSDQYYTPQEEETNEIERQES--QVHDTHVRTRSDDSN------RNDVISTQQMSQIVSCEVRLRDQCKGTTCNRYECPAGCLDSKAKVIGSVHYEMQSSICRAAIHYGIIDNEGGWVDVTRQGRKHYFIKSNRNGIQTIGKYRSANSFIVSKVTVQAVTCETTVEQLCPFHKPASHCPRVYCPRNCMQANPHYARVIGSRIYSDLSSICRAAVHAGVIR-NHGGYVDVMPVDKRRMYTASFQNGIFSESLQNPTGGKAFRVFAVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H336-1", "uniprot_id": "CRLD1_HUMAN", "id": "Q9H336-1", "name": "Cysteine-rich secretory protein LCCL domain-containing 1", "aln": "MKC-TAREWLRVTTVLFMARAIPAMVVPNATLLEKLLEKYMDEDGEWWIAKQRGKRAITDNDMQSILDLHNKLRSQVYPTASNMEYMTWDVELERSAESWAESCLWEHGPASLLP--SIGQNLGAHWGRYRPPTFHVQSWYDEVKDFSYPYEHECNPYCPFRCSGPVCTHYTQVVWATSNRIGCAINLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHGRPCSACPPSFGGGCRENLCYKE-GSDRYYPPREEETNEIERQQS--QVHDTHVRTRSDDSS------RNEVISAQQMSQIVSCEVRLRDQCKGTTCNRYECPAGCLDSKAKVIGSVHYEMQSSICRAAIHYGIIDNDGGWVDITRQGRKHYFIKSNRNGIQTIGKYQSANSFTVSKVTVQAVTCETTVEQLCPFHKPASHCPRVYCPRNCMQANPHYARVIGTRVYSDLSSICRAAVHAGVVR-NHGGYVDVMPVDKRKTYIASFQNGIFSESLQNPPGGKAFRVFAVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9U0-1", "uniprot_id": "E7F9U0_DANRE", "id": "E7F9U0-1", "name": "", "aln": "MKCGHLEDLFSGFVLLVTVQTVVSMVIPNATHLEAILEKYMDKDETWWQSKSRGKRAISQSDMQLILDLHNKLRGQVYPPASNMEYMVWDTELERSAEHWAHTCLWEHGPSHLLT--RIGQNLGAHWGRDRPPTFHVQAWYDEVRDFSYPYPQECNPHCPYRCSGPVCTHYTQLVWATSNKIGCAINVCYNMNVWGMIWAKAVYLVCNYSPPGNWWGHAPYKHGTPCSACPPSYGGGCRNNLCYKDDGSNYHYTPETEENNYIEPEPEPVRSHDTHYRDETTTPSPNENIERNEVSSTSQMSQQVACDTRLRDQCKGTTCNRYECPPGCFYNYGKVIGSGHYDMQSSICGSGLHAGIIDDDGGWLDITRVGRRQRFSKSFKNGVQTLAKNQSANAFTVSNVPVKAVNCETTVAQFCPFKKPVRHCPRLYCPRNCLYDS--YARVIGTRYYADNSSICRAAIHAGVIQSDSGGYVDVMPVDKRKQHKGSYQNGISSESLQNPPGGKAFRVFAVI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFY2-1", "uniprot_id": "Q9VFY2_DROME", "id": "Q9VFY2-1", "name": "SCP domain-containing protein", "aln": "--------MMQPSAVLLTTIMIISCEVAFACNGKIIASGITAEE-----------RSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWS-----TAPLDADDGDFPSRIQSWFNEVQKYSFGDAWSPKTGHYSQLVWGETSLVGCGYAEYKDTSKYNKLY------VCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSSRYQGLCAAP--GSSPAANSVYGANTIETYEYG---YNSSPSSQTANNN---------PPTNNINKSQFSYNQPRPKPVQTINPNPSPFNPQAAVPSASTFGGSSFGSAS---RGGSHAYTTDPS------QSAGRYKHKLEAYRPSAAEFEKSVHKHTILRTYIEQNQQRQDQQQQQQQKEQDQQQQQP-------------------------------------------------------------------EPSSTKKPSRGWSLLTWRG-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*. . : : :. * : : . :: *:* .: : : :: . * * *.**. :.** ** *: **. * :.*.* : :****. *. * ::: .:. . .: :* : :. . .* **:*:**. :. :**. : . :. :: ****.* ** *: **: * *..: .. :.** .. . * ** ::: .: . : . .. .: : . : . * . . ...:*. : * .. * * . ** : :: : . : * ::: : : : : * :. : * ..* ::*. * :: .: ", "identical_positions": 64, "similar_positions": 128, "identity": "12.48%" }, { "cls_id": "homologset.agr.MGI:1934667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AWN9-1", "uniprot_id": "B1AWN9_MOUSE", "id": "B1AWN9-1", "name": "", "aln": "----MEARLLRGCVVEPLFLPLLLLLLLLLGGQGQGGMSGRCDCASESQKR----YGPFCCRGCPKGHYMKAPCAEPCGNSTCLPCPSDTFLTRDNHFKTDCTRCQVCDEEALQVTLENCSAKSDTHCGCQSGWCVDCSTEPCGKSSPFSCVPCGATTPVHEAPTPR---------PCLPGFYIRGNDCTSCPTGFSSVCPKACTAVCGWKQMFWVQVLLG---VAFLFGAILICAYCRWQPCKAVVTADTAGTETLASPQTAHLSASDSAHTLLAPPSSTGKICTTVQLVGNNWTPGLSQTQEVVCGQASQPWDQLPNRTLGTPLASPLSPAPPAGSPAAVLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEICRFRDQQYEMLKRWRQQQPAGLGAIYAALERMGLEGCAEDLRSRLQRGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M411-1", "uniprot_id": "A0ABK0M411_RAT", "id": "A0ABK0M411-1", "name": "", "aln": "MLGLQEWRRCLGGRGRLLGQPQLGQLHVFSSLCSYHRCCCCCYCCLVAMARVVRPAGVTVPVSHRRGQYMKAPCTEPCGDSSCLPCPPGTFLARDSHFKTDCTRCQVCDEEALQVTLENCSAETDTHCGCQSGWCVDCSTEPCGKSSPFSCTPCSS----YEPTTYR---------PCPPGFYIHGNGCASCPTSFSSVCPKACTAVCGWKQMFWVQVLLG---ASFLLGTVLICAYCRWQPCKPVVTADIAGMETLASPQTTHFSASDSAHTLLPPPGSTGKVCTTVQLVGNNWTPGLSQTEEVVCRQASQPWDQLPNRTLGPPLVPPLSPAPPAGSPAAVLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEICRFRDQQYEMLKRWRQQQPAGLGAIYAALERMGLEGCAEDLRSRLQRGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93038-1", "uniprot_id": "TNR25_HUMAN", "id": "Q93038-1", "name": "Tumor necrosis factor receptor superfamily member 25", "aln": "----MEQR-PRGCAA----VAAALLLVLLGARAQGGTRSPRCDCAGDFHKK----IGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICT-VQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * . * :: . . * *. : * . *:*:****:****:*:** ** .***: :.*.:::*:***.***:* **:****** :**:***:.** *:*... * .**** * ** :. . .* **** :*:.*.****. . **: *:*****:*********. ..:*:*: * :* : * *.:**** ** *:*:.* ::*:*. *******.**.*: *:** ******.**** .:*:*.:* *.: .*****.*:**.. ...*** .****** :**************************************** ***********************:*********:**.***********", "identical_positions": 233, "similar_positions": 89, "identity": "54.06%" }, { "cls_id": "homologset.agr.MGI:1934677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VB91-1", "uniprot_id": "Q9VB91_DROME", "id": "Q9VB91-1", "name": "Lipase domain-containing protein", "aln": "--------------------MRVFIALAALLATVSALPIEE-----------------------RVNGENGWYVPQ------------------IDGSFEWMDKQDAEELLN---RNSLIETRS--N----DVSFYLYTKHNPTVGKEIRAD-----------ASS-IEDSHFDKNQGTRFVIHGWNGR-YTDGMNVK-ITRAWLS------KGD------YNVIVVNWDRAQS-VDYISSVRAVPGAGAKVGEMIEYLHEHHHLSMESLEVIGHSLGAHVAGYAGKQVGGKRVHT--IVGLDPAMPLFA-YDKPDKRLSTEDAFYVESIQTNGGEKGFLKP-IGKGTFYPNGGR-NQPGCG--------SDIGGTCAHGRSVTYYVEAVT--EDN-FGTIKCHDYQAALANECGSTYSGVRMGAVTNAYMVDG-----------DFYVPVNGQAPFGKIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB90-1", "uniprot_id": "Q9VB90_DROME", "id": "Q9VB90-1", "name": "Lipase domain-containing protein", "aln": "--------------------MKVFFVLAALLAAVSALPIEE-----------------------RVNGENGWFIPK------------------LDGSFEWMDMQDAEDLLA---NGAQMEGRISTN----AVNFYVYTKSNPTDGKEIKAK-----------SGS-VEDSHFNKDHGTRFVIHGWTQR-YSDDMNTR-ITKAWLS------KGD------YNVIVVDWARARS-VDYASSVLAVPGAGGKVGEMIKYLHDHHGLDYDSLEVIGHSLGAHVAGYAGKTVGDKRVHT--IVGLDPALPLFS-YDKPAKRLSTDDAHYVESIQTNGGKLGFLKP-IGKGAFYPNGGK-SQPGCG--------LDATGSCSHARSVLYYAEAVT--EDN-FGSIKCHDYEDAVAKNCGSTYSSVRMGAITNAYMVEG-----------DFYVPVNSEAPFGKIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB92-1", "uniprot_id": "Q9VB92_DROME", "id": "Q9VB92-1", "name": "Lipase domain-containing protein", "aln": "--------------------MRELFFLAALLVAGNALPIEE-----------------------RINGENGWFVPQ------------------EDGTFQWMDKKDAKELLE---NISPLEFRS--N----EVSFYLYTKQNPTEGQEITAD-----------ASS-IVASHFNKDHGTRFVIHGWKGK-YTDSMNVD-ITKAWLS------KGD------FNVIVVNWARSQS-VDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVIGHSLGAHVAGYAGKQVGQKRVHT--IVGLDPALPLFS-YDNPDKRLSSEDAFYVESIQTNGGVKGFVKP-IGKAAFYVSGGR-KQPGCG--------VDLAGTCSHARSVIYYAEAIT--ENS-FGAIQCQDYQAALDNECGSSFSSVRMAEDTNAYNVEG-----------HFYVPVNSEAPFGQTE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB89-1", "uniprot_id": "Q9VB89_DROME", "id": "Q9VB89-1", "name": "Lipase domain-containing protein", "aln": "--------------------MKTFLILAFFALAASAIPIKES---------------------ERVHGENGWYVPQ------------------EDGTSEWVDMDVAEQWME---AQELLESRGLTTV---PVKFYLYTSSNPTKGKKITAS-----------TKS-IDASSFNSAHPTRFVIHGWTQS-YTASMNKD-IRSAWLS------RGD------YNVIVVDWARARS-VDYATSVLAVAATGKKVAKMINFLKDNHGLNLNDLYVIGHSLGAHVAGYAGKNT-DGQVHT--IIGLDPALPLFS-YNKPNKRLNSDDAWYVESIQTNGGTLGFLKP-IGKGAFYPNGGK-TQPGCG--------LDLTGACSHGRSTTYYAEAVS--EDN-FGTMKCGDYEEAVSKECGSTYSSVRMGADTNAYMVEG-----------DYYVPVNSKAPFGMIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB88-1", "uniprot_id": "Q9VB88_DROME", "id": "Q9VB88-1", "name": "Lipase domain-containing protein", "aln": "--------------------MKTFLILAIFALAASAYALEES---------------------ERVNGENGWYVPQ------------------QDGSFEWVDMDVAEEWME---AQEKLEGRGLTTV---PVNFYLFTPKNPSSSKHIYAT-----------TKS-ISKSNFNPAHPTRFVIHGWTQS-YLNSMNSD-IRKAFLS------KGD------YNVIVVDWARARS-VDYATSVMAVAATGKKVAKMINFLKDNHGLNLNDVYVIGHSLGAHVAGYAGKNT-DGQVHT--IIGLDPALPLFS-YNKPNKRLNSDDAWYVESIQTNGGTLGFLKP-IGKGAFYPNGGK-TQPGCP--------LDVTGACSHGRSTTYYAEAVS--EDN-FGTMKCGDYEEAVAKECGSTYSSVRMGADTNAYMVEG-----------DFYVPVNSKAPFGMIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB93-1", "uniprot_id": "Q9VB93_DROME", "id": "Q9VB93-1", "name": "Lipase domain-containing protein", "aln": "-------------------MMKLFLALAFCVLAANAVEV-------------------------RVNGENGWYVPQ------------------ADGTMEWMDREFAEAYLE---TKNRMEGRNVLN----PVTFYLYTNSNRNSPQEIKAT-----------SAS-ISGSHFNPNHPTRFTIHGWSSS-KDEFINYG-VRDAWFT------HGD------MNMIAVDWGRARS-VDYASSVLAVPGVGEQVATLINFMRSNHGLNLDNTMVIGHSLGAHVSGYAGKNVKNGQLHT--IIGLDPALPLFS-YDSPNKRLSSTDAYYVESIQTNGGTLGFLKP-IGKGAFYPNGGK-SQPGCG--------VDLTGSCAHSRSVIYYAESVT--ENN-FPTMRCGDYEEAVAKECGSSYSSVRMGATTNAYMVAG-----------DYYVPVRSDAPYGMGN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB94-1", "uniprot_id": "Q9VB94_DROME", "id": "Q9VB94-1", "name": "Lipase domain-containing protein", "aln": "--------------------MRLCLLVLGCVIAASAWPVDQLS--------------------VRDHGINGWFVPQ------------------REGGLRWIGKAEAERQLEYYEAQEALEGRLSTN----TVNFYLYTLQNPSTGQQIKAT-----------QDS-IDGSFFNPQNPTRITIHGWNSN-YKDGVNTR-VADAWFQ------YGD------YNMIAVDWLRGRS-LEYASSVAGAPGAGKKVAALVDFLVEGYGMSLDTLEIVGFSLGAHVAGHTAKQVNSGKVGK--VVGLDPASPLIS-YSNTEKRLSSDDALYVESIQTNGAILGFGQP-IGKASFYMNGGR-SQPGCG--------IDITGSCSHTKAVLYYVEALL--WNN-FPSIKCESSVDANKNNCGNTYSSVFMGASINFFVAEG-----------IFYVPVNKESPYGLGELNSGGEATTGTPEITSTTVDGEDESTTEVSTSTTTDKPEESTTEEPEEDSTTNGKPEESSTTTEQPEDSTTTTEEPIDSTTEAPEDESTTSSPTDGGEQSTTEEPETTTEKPEETSTSPIDTEDSTTKEPEDVSTTPKESEESTTSSPEDDDTTSAPGEDDDTTAAPGGDEEETTTEDPEETTTSPSDADDSTTEEPEEDTTTTKKPVEPSTTTEEPEDSTTEVPEESTTEEPDKETSTTNAEPEVTTTVEPDVDSTVDPEGDQSTREDLEDVSTTAVPTKLPSTTGVPPEVPITTLAPEVPSTSPPQDGNTKNIFIFNVFLVNVKIENKS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9P0-1", "uniprot_id": "Q9V9P0_DROME", "id": "Q9V9P0-1", "name": "Lipase domain-containing protein", "aln": "---------------MRTHLFALCLSMATIGIPKANGVMDDYDAEMGEFMNALPNLDDTPYGLGQRSDISTEPEEDDILASLDDEYEEAKHCVWNTCDKDLSESRGIGKFLDLPFIKKIASNLNPFGSKKLRMHFYLFKREFPECGREVDFS-----------IERKWRHCGFNASLPTRLMIHGWMSQ-SRGSFNRD-VKNAYLK------KGE------YNVIVVDWSASSANINYFSVVKLIETFGAELAQFIRNLNRQFGADFDSMYLIGHSLGAQIAGSAGKRLKPVKVNT--IFALDPAGPKFR-HRGTEFRIDPSDAKYVESMHTSAN-FGFRRP-TGSATFYPNYGA-YQHSC-----------YYLGCSHIRSYQMFAESIN--SPLGFWGTPCIR-DNGRWQCDYSQRQSIQMAGEP-SIHKEG-----------IFYVKTSSSDPFALGKQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ96-1", "uniprot_id": "Q9VQ96_DROME", "id": "Q9VQ96-1", "name": "Lipase domain-containing protein", "aln": "---------------MISQLGRISI-MSAVLLAFAAIVFAS-------------------------SSEKTELDPN------------------ATCNYTLVKKKTLG--VDPSFWKKFFKHLIPFTSSRGKMQFILFKRDFADCGRELFVG-----------DVENLRNSGFDARHQTRIVIHGWMSQ-SKGSHIRK-VKNAYLSLTDPGPNGEPAPYEDFNVIVCDWSKTSTNVNYYEVAKTVEDMGALLAELVRYLNQEANMHYDDVYVIGHSLGAQIAGSAGKQIMPYRFNT--IYALDPAGPQFR-EKSDEYRIDASDASYVESIQTSVS-FGFEQP-VGHATFYPNYGK-NQKKC-----------YVYGCSHKRSHDYFIESLT--SPAGFWGPRCERHDDGTWLLLMSDGE-FRMGGEP-SIPKNG-----------TFYVKTYSKPPYAMGHRWQTEPPPREDDIENSTEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97535-1", "uniprot_id": "PLA1A_RAT", "id": "P97535-1", "name": "Phospholipase A1 member A", "aln": "--------------MCPGLWGTCFWLWGSLLWLSIG----------------------------------------------------------RSGNVPPTTQPKCTDFQS----ANLLRG------TNLKVQFLLFTPSDPGCGQLVEED-------------SDIRNSEFNASLGTKLIIHGFRALGTKPSWINK-FIRALLR------AAD------ANVIAVDWVYGST-GMYFSAVENVVKLSLEISRFLSKLLELG-VSESSIHIIGVSLGAHVGGMVGHFY-KGQLGR--ITGLDPAGPEYT-RASLEERLDSGDALFVEAIHTDTDNLGIRIP-VGHVDYFVNGGQ-DQPGCP-AFIHA--GYSYLICDHMRAVHLYISALE--NTCPLMAFPCASYKAFLAGDCLDCFNPFLLSCPRIGLVERGGVKIEPLPKEVRVYLQTTSSAPYCVHHSLVEFNLKEKRKKDTSIEVTFLGN-NVTSSVKITIPKDHLEGRGIIAHQNPHCQINQVKLKFHISSRVWRKDRTPIVGTFCTAPLPVNDSKKTVCIPEPVRLQVSMAVLRDLKMACV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI78-1", "uniprot_id": "PLA1A_MOUSE", "id": "Q8VI78-1", "name": "Phospholipase A1 member A", "aln": "--------------MRPGLWETCFWLWGPLLWLSIG----------------------------------------------------------SSGNVPPTTQPKCTDFQS----ANLLRG------TNLKVQFLLFTPSDPSCGQLVEEG-------------SDIRSSEFNASLGTKVIIHGFRALGTKPSWIDK-FISAVLR------AAD------ANVIAVDWVYGST-GVYYSAVENVVKLSLEISRFLSKLLELG-VSESSIHIIGVSLGAHVGGMVGHFY-KGQLGQ--ITGLDPAGPEYT-RASLEERLDAGDALFVEAIHTDTDNLGIRIP-VGHVDYFVNGGQ-DQPGCP-AFFHA--GYNYLICDHMRAVHLYISALE--NTCPLMAFPCASYKAFLAGDCLDCFNPFLLSCPRIGLVERGGVMIEPLPKEVKVYLLTTSSAPYCVHHSLVEFYLKEKRKKDTSIEVTFLSN-NVTSSVKITIPKQQLEGRGVMAHPNPQCQINQVKLKFQVSSRVWRKDRTPVVGTFCTAPLPVNDSKKTVCIPEPVRLQAGVPAFQDLKIACV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53H76-1", "uniprot_id": "PLA1A_HUMAN", "id": "Q53H76-1", "name": "Phospholipase A1 member A", "aln": "--------------MPPGPWESCFWVGGLILWLSVG----------------------------------------------------------SSGDAPPTPQPKCADFQS----ANLFEG------TDLKVQFLLFVPSNPSCGQLVEGS-------------SDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDT-FIRTLLR------ATN------ANVIAVDWIYGST-GVYFSAVKNVIKLSLEISLFLNKLLVLG-VSESSIHIIGVSLGAHVGGMVGQLF-GGQLGQ--ITGLDPAGPEYT-RASVEERLDAGDALFVEAIHTDTDNLGIRIP-VGHVDYFVNGGQ-DQPGCP-TFFYA--GYSYLICDHMRAVHLYISALE--NSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSS-NITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFCTALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYZ4-1", "uniprot_id": "PLA1A_DANRE", "id": "Q6NYZ4-1", "name": "Phospholipase A1 member A", "aln": "---------------MAWKWIKAFVYLSVCVTSALG----------------------------------------------------------DDEEASAS---KCADFNN----TTWLEYRQA---TKLQVQYLLLTRKNANCASLFTQDC---------LNHTQKHTAYFNSSLPTKVIVHGYRALGSKPSWVSG-LAQALLR------EED------VNVLVVDWVYGAS-FAYNLVVENYKEVAVQISVLINQLTKYG-STLESFHFIGVSLGAHVSGFVGTLF-HGKLGR--ITGLDPAGPMFK-SADPFDRLDSSDALFVEAIHTDSDYFGISIP-VGHVDFFLNGGM-DQAGCARSRFAS--MYGYVICDHMRALHVYMSALN--GSCPLIGFPCSGYEEFLAGKCITCDDPFNGTCPQIGLLKNSGITATPLPNQEKVYLLTTASGPFCAHHILVELNVS-RLDKTAEVQLILKSIGHPETELNLKLYTDETRYKTVAAHPEQLCKIDSMQLIN-TGGRFYRQG-DIHFEYICISEIPQTRGMDPLCVKN-IHIGRGVPWSHDFVQVC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAL5-1", "uniprot_id": "A1ZAL5_DROME", "id": "A1ZAL5-1", "name": "Lipase domain-containing protein", "aln": "---------------MVLTAASTLCNVFTFLLAGSPIFYS------------------------------------------------------AAPRGSCSTCCAIKERED--------------------IKFMLYTSRNRNSAQLLHLS-----------DDARLAQSNFNFNYPLAIYLHGFSESATGERQSSQELKDAFLR------RGN------YNVILIDWSAMTAVPWYSNAVENLPVSGRYLARFLRFLVDKG-YPAKYIHLIGFSLGAEVAGFAGKQLQEWGIKLPRITALDPALPLFE-GNSSNRRLSPSDARFVDVIHTDGGLLGNPAP-MGHADFYPNGGRPLQPGCAKQNIANNWLGIIVGCSHQRAWEYFVESIA--QPRGFPAQRCEPSDMFG--ICREPGGGPAFMGMGADPRIRG-----------KFYLDTNDAKPFGRNSRARAIVSLAPRLPIAYKLPPNATRQPSVSRWANGQKEQDNEDEDNNALSNNIDRFSLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8T1-1", "uniprot_id": "Q0E8T1_DROME", "id": "Q0E8T1-1", "name": "Lipase domain-containing protein", "aln": "------------------MMNNILVLIGFSSVMLVAG---------------------------------------------------------LDDMNCFSLQNEICPNAN--------------------ISFWLYTKENQEGTKLSVFE---------------LNRFEFYHHKPLKVLIHGFNGH--RDFSPNTQLRPLFLT-------QD------YNLISLDYPKLAYEPCYTEAVHNAKYVARCTAQLLRVLLESGLVKIEDLHLIGLGLGAHVAGFIGQFLPEHKLEH--ITALDPAKPFYM-VKDPALKLDPTDAKFVDVVHTDVTMLGLLDA-VGHVDFYLNMGV-SQPNCG-----PINKMETHFCYHNRAADYYAESIS--SPSGFYGFYCPNFKSFAKGICIPDKNIELMGFHVDPKARGR------------YFLDTNNGPPYAKGENFTSISRQLKGRTFVNDDIIDKLIGT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VEY9-1", "uniprot_id": "Q9VEY9_DROME", "id": "Q9VEY9-1", "name": "", "aln": "------------MGSLTGMHISHWLLWTCLLLLGAAGTDASVD-----------------------------------------------YFAYAPGKCEVSISDVIQGMIT---TEAGVILGRPRPSQTKLLRYDLYTPLNPEERQLLRPG-----------DLTMLRNSHFNPKWPVRVSIHGWAGK--SVTCSNAAIKDAYLS------RGN------YNVIILDWSRQSLDISYPRVSKQLPSIAANVAKMLRFLHDNTGVPYEQIYMIGHSAGSHISGLTGKLLRPHRLGA--IFALDPAGLTQL-SLGPEERLDVNDALYVESIHTDLTLLGNPSTKLSHASFFANWGL-GQPHCP----NATATEFDFVCDHFAAMFYFAESVR--QPKSFAALRCSSAKSVLSATCNCNVGGSEKYAVNTCTGNEFMGGEPAVPKRGIFYLSTRPQSPYGTSDGLVHIKRPRPSTIRETANRRSIG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLU1-1", "uniprot_id": "Q9VLU1_DROME", "id": "Q9VLU1-1", "name": "Lipase domain-containing protein", "aln": "MSSNALACICNVINPCRNEVSTTFVVVQWLITGFAALAQVVRP-------------------VLLLFGIRGEVALN-----------------QEDYNKTWIYMPNGQGKPE--VAYLVEPPPENRINLPQLIKFELYGSDSSSSADFWIDENNFEFPQRHKRDTWQEMAEKFNPELDTKILVHGWKSS--TMSNSIQSIRGAYIE------RGQ------VNVFAINWKDQADNIYYLTPARYTVQVGRAVAKLIDLLVEEKDADPNRIHLIGHSLGAHIMGYAGSYT-KYRVNR--ITGLDPARPAFEDCIGPENHLDDTDANFVDVIHSCAGYLGFRKP-IGMVDFYPNGGGPPQPGCK------ELSQIFTGCSHGRSYEYYAESIN--SPKGFYGVPCSGLDELKGKNCT---GGKILMGDPVPREARG-----------IFFVKTANKPSYALGIDDLWSN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBQ2-1", "uniprot_id": "Q9VBQ2_DROME", "id": "Q9VBQ2-1", "name": "Lipase domain-containing protein", "aln": "--------MMMRMRNRGGKRLQANYFDTQMPLLSSGLMSPGQLPILDEQHGRQEQLERHYLAHGPSSVEQQLLRLQPDYKLLYSAEHHTYFHLHTLVPQDNANRQTGPLKSEKESPHRRLFQQVVGNTLTAAFGLNVMNKGDQEQNQQFTSEPVN------LYDAASLRRSRFSPFNPTRILIHGWLGN--ENANMYNELLPAYFDLR----NGN------YNIFTVDWGRGAI-ADYITASYRVKPVGQVLAKFVDFLHQEAGMRFEDLQLVGFSMGAHVAGLAGKHLQTGRLRM--IRALDPALPFFR-YAKPKERLTAEDADYVEVLHTSVGSYGFDRP-VGHVDFYANWGS-QQPGCF-----------WHECSHWRAFMLFAESLARDQATGFLSQGCPAAEWQQLTRFHRCPKDTGVMQTMGGDLANVSAEFLAQ-RQGVYYFQTNDQPPYVLAQNASSKRAAHIQENKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . :**: . : : *:: :: * . . :: : . .:* . *:.: * . . : .**** :: ** :*: ::: * . . :: . * * * * * : : .:: : * :. . .: ", "identical_positions": 22, "similar_positions": 51, "identity": "2.78%" }, { "cls_id": "homologset.agr.MGI:1934682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U1W7-1", "uniprot_id": "EMC9_RAT", "id": "Q5U1W7-1", "name": "ER membrane protein complex subunit 9", "aln": "MGEVEISARAYGKMCLHASRYPHAAVNGLLLAPATRSGECLCLTDCVPLFHSHLALSVMLEVALNQVDVWATQAGLVVAGYYHANAVLDD-QSPGPLALKIAGRIAEFFPNAVLIMLDNKKLVTWPRVPPVIVLENQGLQWVPKDKNLVMWRDWEESRQMVGALLEGRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWSGSTDGHA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB76-1", "uniprot_id": "EMC9_MOUSE", "id": "Q9DB76-1", "name": "ER membrane protein complex subunit 9", "aln": "MGEVEISARAYGKMCLHASRYPHAAVNGLLLAPATGSGECLCLTDCVPLFHSHLALSVMLEVALNQVDVWGAQAGLVVAGYYHANAVLDD-QSPGPLALKIAGRIAEFFPRAVLIMLDNKKLVTRPRVPPVIVLENQGLQWVPKDKNLVMWRDWEESRQMVGALLEGRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWSGSTDGNA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3B6-1", "uniprot_id": "EMC9_HUMAN", "id": "Q9Y3B6-1", "name": "ER membrane protein complex subunit 9", "aln": "MGEVEISALAYVKMCLHAARYPHAAVNGLFLAPAPRSGECLCLTDCVPLFHSHLALSVMLEVALNQVDVWGAQAGLVVAGYYHANAAVND-QSPGPLALKIAGRIAEFFPDAVLIMLDNQKLVPQPRVPPVIVLENQGLRWVPKDKNLVMWRDWEESRQMVGALLEDRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWVGPTNGNGNA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1Y1-1", "uniprot_id": "EMC89_DROME", "id": "Q9W1Y1-1", "name": "ER membrane protein complex subunit 8/9 homolog", "aln": "MCDYKVSERAYAKLIFHAAKYPHQAVNGLLLAEKTSKGSQVEIVDAIPLFHQCLYVTPMAEVALMLIDAHAEREGLVIAGYYAAPENFYDNQVDKTPAAKIADKIQENFKNACFVVVDNKLMTLQHDRAAIQVFNCPGDSGARWSKAKFTLSQASDTLEGVSLLLKRGAMRDLVDFDNHLDNPDKNWTNDFLNQPLNDLQKLY------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ::* ** *: :**::*** *****:** . .*. : :.*.:****. * :: * **** :*. . : ***:**** * . * * . * ***.:* * * * ::::**: :. ..: *:: * . .* . : .:: : *. **: * :.***** ***: ::***: ** :.: ", "identical_positions": 70, "similar_positions": 59, "identity": "33.49%" }, { "cls_id": "homologset.agr.MGI:1934704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU29-1", "uniprot_id": "E9PU29_RAT", "id": "E9PU29-1", "name": "RBR-type E3 ubiquitin transferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGDEE-RAFLAAREELASALRWDSA------------------QVFPLEQLTPLLATSLPLSSRYRQLDAGRLVRCNAHGEPRNYLN---------------------TLSTALN---------------ILEKYGRNLLSPQRPRYWRSVKFNNPVFRSTVDAVQGGRDVLRLYGYTEERPDGLSFPGGQEEPDEYQVAIVTLEVLLLRTELNLLLQNTHPRQNALDQLLRDSVEDDMLQLSEFHPLLREIVPGPL--PSAPGHTPGPCFLCGSAPGTLHCPACNQASCP--------------------------------------------------ACDLLFHG----------------------HPSRAHHLRHTLPGAHQTTNLSSSLP------------------------------------------------------ASSQPRPHSSS-LAMGDSSLSSPDPANACLPWHCPTCATLNEPWAVFCAACSQPKGCKVRGR-----ESSQGTGVLEPEPARDQWACQSCTFENEAAAVLCAICERPRLAQPPSLVVDSHDAGVYQQPLKQEDTLLSAAQSQVWHCDHCTFCNSGPVWVCAMCNRTRSPIPAQP----YPSSLEKGLSQPGSSQHLSSSLPASCGDPEKQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------RQDKMRKESLQLVNMIQEGEAAGASPEEIFSALQYSG-TEVPLQWLRSELSYVLEMVAELAGQRDPE-----LGAFSCQEARKAWLDRHGNLDEAVEECVRARRRKVQELQSLGFEPKEGSLQALFQHGGDVARALTELQRQRLEPFHQRLWGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPEPTPCWD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLDRQSLVRRLLAVYTLPSWGRAELALALLQETPRN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELLDVVEAVRHSQDRAFLRR-----------LLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLT----DDAQLLSYFSTLDIQLRESLEPDAYALFHKKLTEAVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWPAARLQKLLQDNNVMFNTEPPAG-------TRAVPGGGCRVMEQKEVPSGFRDEACGKETPPGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATARYLHLTPQPMDGEDLPAYQARLLQKLREEVPLGQSIARRRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924T7-1", "uniprot_id": "RNF31_MOUSE", "id": "Q924T7-1", "name": "E3 ubiquitin-protein ligase RNF31", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGDEE-RGFLAAREELASALRWDSA------------------QVFPLEQLMPLLATSLPPAARYLQLDAGRLVRCNAHGEPRNYLN---------------------TLSTALN---------------ILEKYGRNLLSPQRPRYWRSVKFNNPVFRSTVDAVQGGRDVLRLYGYTEERPDGLSFPEGQEEPDEYQVAVVTLEVLLLRTELSLLLQNTHPRQNALDQLLRESVEDGMLQLSEFHPLLREIVPGPR--PSAQGSTPGPCFLCGSAPGTLHCPACNQVSCP--------------------------------------------------ACDILFHG----------------------HPSRAHHLRQALPGSHQTASLSSSLP------------------------------------------------------ASSQPRPPSSS-LALGDSSLSSPDPANACLPWHCLTCATLNEPWAVFCAVCSQPKGCKVPGI-----EGSHGTGGLEPEPARDQWACQSCTFENEAAAVLCAICERPRLAQPPSLVVDSHDAGVCQQSLKQEDPLLTAAQPQVWYCDHCTFCNSGPVWVCAMCNRTRDPIPTQPALQSYPSSLEKGRPKPGSSQHLGSSLPASCGDPEKQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------RQDKMRKEGLQLVSMIQEGETAGASPEEVFSALQYSG-TEVPLQWLRSELSYVLEMVAELAGQQDPE-----LGAFSCQEARKAWLDRHGNLDEAVEECVRARRRKVHELQSLGFGPKEGSLQALFQHGGDVARALTELQRQRLEPFHQRLWDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPEPTPCWD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLDRQSLVRRLLAVYTLPSWGRAELALALLQETPRN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELLDVVEAVRHSQDRAFLRR-----------LLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLT----DDAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAG-------TRAVPGGGCRVMEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATIRYLHLAPQPADGEDLPAYQARLLQKLREEVPLGQSIARRRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EP0-1", "uniprot_id": "RNF31_HUMAN", "id": "Q96EP0-1", "name": "E3 ubiquitin-protein ligase RNF31", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEEEERAFLVAREELASALRRDSG------------------QAFSLEQLRPLLASSLPLAARYLQLDAARLVRCNAHGEPRNYLN---------------------TLSTALN---------------ILEKYGRNLLSPQRPRYWRGVKFNNPVFRSTVDAVQGGRDVLRLYGYTEEQPDGLSFPEGQEEPDEHQVATVTLEVLLLRTELSLLLQNTHPRQQALEQLLEDKVEDDMLQLSEFDPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCP--------------------------------------------------ACDHLFHG----------------------HPSRAHHLRQTLPGVLQGTHLSPSLP------------------------------------------------------ASAQPRPQSTSLLALGDSSLSSPNPASAHLPWHCAACAMLNEPWAVLCVACDRPRGCKGLGLG---TEGPQGTGGLEPDLARGRWACQSCTFENEAAAVLCSICERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTFCNSSPGWVCVMCNRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------RQDKMREEGLQLVSMIREGEAAGACPEEIFSALQYSG-TEVPLQWLRSELPYVLEMVAELAGQQDPG-----LGAFSCQEARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQHGGDVSRALTELQRQRLEPFRQRLWDS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPEPTPSWD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPDKQSLVRRLLAVYALPSWGRAELALSLLQETPRN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELGDVVEAVRHSQDRAFLRR-----------LLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLT----DDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAG-------ARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IPJ3-1", "uniprot_id": "LUBEL_DROME", "id": "Q8IPJ3-1", "name": "E3 ubiquitin-protein ligase lubel", "aln": "MTTHQLLNKNVRTMPSWVMEANDRIGPKPPPTPPNGVAGGLPKAPALPPKAKSTPEPDYEIIEFSSQQYSNEPMKTTVIRTKTPDNKLKCTLCGSQNPWVTCAECAGQIFCASCDDMFHKHPKRKQHMRKAVEQGTPPIPPKAQAGGGAPPPVAPPRRSKRGLLTPFLGRKDQMLPPPSPTPSHKSLGGWRGSLGGGATPPVPPIATSSANQMNNRPLPDPPRSEGGGSSRSGTPKSVFDTIQRPPSVQLEKIKSKASATLDRMAILQQRYRQQKARQDLSANSEQHLSNEAGFEHWSNISPSPSHFRSGSMSSGLNSSHFDLSDDSQFHNSLLLQQRQAAGAQRRQMSTSVFNLNSNPRRPLSEAQNGGAWLANQRIQQAQSLAQLNCAGCQQSQQHPGWAQHPHQALPQHQHPDQWSQFGSQQQFNNSNLSLNVGPGYMSQQHHPHYPPPVFMTQRGMMPNVYPGAPGYPMMHPGVMGMPPSAASRAASRSRYAASPTPSRKSMSLRRKRNSYVDDELTDDEDSDQDDRRSLVSNRSGMTSASRSQHHQNHIQPRQRRLSSASQLIASDELDGDQVHHKMRNRRGSIAKSVQSEWLPERRENEGTLTRNKTATDSARTSRIYSDLESEGSGARALVQAKIQQKLQEADQHKSSKKAEPKRKPEMKDENTQAAAVVQKVVVPPAHEESASEYEEVVEEVTASESEAEAQTAPDPQEVPDEIGADDLGPPPSTPDHEWECEFCTFVNEPNIKICSICCKTPSKPPVQPNKAKKVEEKPQPPAEKSNNIKASSKTETKPVQKPTTKSQQPSQKSVAALSKTTHTNSTSSSKASPAVNSKTTSSIPIKTPSKSTLKTSSENESDNSLAKSLLHKESVENIWNTLDESIQAQAEQVLKKAQKVSTACGGTPPREIAAVEMGTSPPPQSISTQTYDALPFNTKQEEIIPVVPDRFTTPEPNKMERRPHYRSNSQLQQESERYRSANDLRYHDGFGLDPYSAGLVTKRPNFINELRMLQLQVSSPFDMPHETFGVKHEPARDPETEMHIILKELELYKFTVEELEAALKYCSPETHPIQWLRENWHKLVQTVQSLSTKYGQERGENTIGTVSQNEAREALRNSGGNVWQAVADCIQQRQQKYRKLAAKGNFLRDDIVNALTAHQGNVEQALVELNRTQLKPFLMRIWGSPNGVENESGVAIDTKSDIHDFLNTHALDCLQPPLAGQSPSPAQANPFDQPRTDESPVKSTYATPSPYQMEDSTLKNLEILIGNMEQNQAKQNQEVLRSIETMLDTFKGKPELEYETDPEIMRILTKSPISTMKPSGPAEDKSTDDVKNFVWQHIQEIVPNLVQQVEQELMEKPEEVAKIEAEQPKEPEPLLEPQPEPTPSVDPAVYIMEEVIKPNLREASIREEVQPSFIYATEIANFKLEFDRGTERWHEAEWESSDLTDAERIVYKCYMAPNEQPKEDVVDVAVESSVNSLPTAKAQEESAPEVPIEAQKIENTEVTQPETVNEELRQQEKLETPLVITSETISETVSQTANESDKQKSIENNLQIKQNVAEVQVQSDDQPSTSRDANRRAKRSQQSRKGRSREQSQKPTNRTKLPNNIDQKVNESKTAAKETEAVKDKDLSAAASNIQSDVTASDPKTSTPLKILSEGTNSNTLETMENVTSTDINDNVTIEVISNRSEEVPAIQDLGKTKDISEPTANPIEEITSIQNSTTISEQSEGPQEPEIPIEVSETTEALQVPREEASIEIVSPPNEEQTKSPTSQEVNIQDTSHIISLPITDVTPTPEIINIAPSTSSISKEQKQSPKRLSKIPVRTLSSSSLRSESRSSNRTPTANDEIEREETTSQGVPIGETVSSPKSEQLSDNQEVNLVSQETQSKKDTNIVEEPATQPLGLELEEHSPNATAVAVSPTDSDEVFEDAPEFSGSDGTRPHDETASDAELYSLDSDGQRAETKSPEDEVVILLDEESQMESSIAQSESNASLDSHSSESETSKVVLKEFVPSGDPAKQNLSELVEDTQRLIKQMRDEISMDEFESTDEDEYSDEYSDEYDEGEEEEWYDSEGEEEGDFDGEEGNTYNEHASYIEEASTGDEGTEIEDIMEEDEDLADDDEPLQSQIPLDIEPVISPALSVTPTNQETDTIAHTEVVSSTGTRLETELPNPAMESILPSQSVQEDIKVEAIPIQSAPPIADSETRPAEQPVELVLEIPSEVEPTPVEEPTALPITPAPPIVDSESRPVEPPVETVLEEPKKVTPSMKGKTANSGTASKGPSTSSSTKTNKSTVSKIPKPTNEPTNKSNSTPLNKKVPLRSKSFSAPMGISSVKRIQEVYLQKQSSSIATSRVPLKSSPVTKKSINDAISRFNSNQADGPSTSGAAAAAAAALLKPRSQPRIPKKKYHETCFSDDDYETSATEEEQEEPNLAEPQKAEQLKRKMSMPVFRAYPSVQEPVIEDPAILARKYVDQELVTNIAEAQIAATLVSMKFSEDVALWAARECSDLDQAIAMLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDNDVHELFQRKLRDRSLLQDPNFKWCIQCSSGFFARPKQKRLICPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRDKIPLQLQFLLKEQNVKFDTEPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYLAGKVAKAGIDPLPIFDLTDCVQELRRRGIALPERGPWDTDEIYKNMCSEVIKKHIPLKSA------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . .. *... * :.. . **:: . :::* : * : .* : .:..::*. ::*:.** :* : : : :* .::*. *. :* :** : . : *. . *:. :. * . :.* : . . * :* .:* : . * * . . : . *.. :** :: .. * ..:.. . . *. .* . .:.** : * : * ** :* :..* .. : ::. :: . * * :.: :* . . ..... . . * . *. . .* *: *** **. :*:** :. * . .: . :: : : ::::.:. : * .. * .. . . : .: .* .. :.* :*. : ..: ::: *. :: :::* * **: :**:*.. *:****.: ::: * .*: : . :*:.* :***.* : **: :** :*:: *::* ::* : * .:. ::** * *:* :**.**:* :*:** *:*. *****. * . :*.* . : . * . * *::: ::.* .: :: .: :::.*:* *: :* *** :* : * *:* :: .* . * :* :.:**: :.:: *.* ** * *:*: .: : *.***.*** *:. *: *.: **::** : *::**:* ** *** **: . :* . **:* .. *.:*:: **.**.* *** : :*** **** ****: :* :********** *:********* ****:.:** ** ..* **. .. .* .**.****:******* . :** **:::** *:*** ::* . . * : ***. .*: * .*..*.* :**:*::** ***.. : .:** .:::: : * *: : *: : : :.:** .: ", "identical_positions": 274, "similar_positions": 351, "identity": "9.45%" }, { "cls_id": "homologset.agr.MGI:1934754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIM7-1", "uniprot_id": "SYK_RAT", "id": "Q5XIM7-1", "name": "Lysine--tRNA ligase", "aln": "MLMQAAVRLVRGSLRQTSWAEWG-QRELRLGQLAPFTTLRKDKPLSDRRSELKRRLKAEKKLAEKEAKQKELSEKQLNQTTAAAATNHTADN--GVGAEEETLDPNQYYKIRSQAVQQLKVS-GEDPYPHKFHVDISLTQFIQEYS-HLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVHINNKLRRGDIIGVEGNPGKTK-----KGELSIVPREMTLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMLSGMVRSITGSYKITYHPDGPE-GQAYEIDFTPPFRRISMVEELEKVLGVKLPETSLFETEETRKILDDICVARAVECPPPRTTARLLDKLVGEFLEVTCISPTFICDHPQIMSPLAKWHRCKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVTMFLTDSNNIKEVLLFPAMKPEDKKETATATETPESTEASPSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MN1-1", "uniprot_id": "SYK_MOUSE", "id": "Q99MN1-1", "name": "Lysine--tRNA ligase", "aln": "----------MATLQESEVKVDG-EQKLSK-------------------NELKRRLKAEKKLAEKEAKQKELSEKQLNQT--ASAPNHTADN--GVGAEEETLDPNQYYKIRSQAVQQLKVT-GEDPYPHKFHVDISLTQFIQEYS-HLQPGDHLTDVTLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVHINNKLRRGDIIGVEGNPGKTK-----KGELSIIPQEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIVRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMLSGMVKSITGSYKITYHPDGPE-GQAYEVDFTPPFRRISMVEELEKALGVKLPETSLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCISPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRLTMFLTDSNNIKEVLLFPAMKPEDKKETAATTETPESTEASPSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15046-1", "uniprot_id": "SYK_HUMAN", "id": "Q15046-1", "name": "Lysine--tRNA ligase", "aln": "----------MAAVQAAEVKVDGSEPKLSK-------------------NELKRRLKAEKKVAEKEAKQKELSEKQLSQAT-AAATNHTTDN--GVGPEEESVDPNQYYKIRSQAIHQLKVN-GEDPYPHKFHVDISLTDFIQKYS-HLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTK-----KGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE-GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W327-1", "uniprot_id": "Q9W327_DROME", "id": "Q9W327-1", "name": "Lysine--tRNA ligase", "aln": "MFARCALRTVQGSWPR--CRYTGIQPLAAG----------------FHVSAPQMEPSKQTKLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQELKRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQVMASAKSYKSEADFEIDTSKLRRGDIIGVVGHPGKTK-----KGELSVMPSEIKLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETPMMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYADIMDITEQLVSGMVKAIRGSYKVIYHPEGPE-GPEQELDFTPPFKRVSMIKTLEEKLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFPAMKPEDANRTAAETAPTAQQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15180-1", "uniprot_id": "SYKC_YEAST", "id": "P15180-1", "name": "Lysine--tRNA ligase, cytoplasmic", "aln": "----------MSQQDNVKAAAEGVANLHLD----------------------EATGEMVSKSELKKRIKQRQVEAKKAAKKAAAQPKPASKK---KTDLFADLDPSQYFETRSRQIQELRKTHEPNPYPHKFHVSISNPEFLAKYA-HLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDPDSYEKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFTTCEFYQAYADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNFSRPWKRINMIEELEKVFNVKFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDKLVGE-LEDTCINPTFIFGHPQMMSPLAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFPTLKPDVLREEVKKEEEN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . .* *. : . : *: .: :: : :.*.:*:: ** :::*: . :********. * :*: :* *: *: * : .:.:***:** * **.** ** *:*:**::*:*:. :.* . .: . *:****:** * *:*: :**:*:. .: **:******* ***:**:*****:******:*. .*::* *::** *:* ***. *:*:******:*.***.****:*:**:*.*:::*******: * *****:****************:************ **** *:*::** :.* **: * *** : ***: .: . :::*: *::*:.*:: **: : :*:* . :.: ** ::*..: . . :***.* *.**:******* :* *:.**** ***:******: * ** ****:** .*************. ** **:** * ***** ::**.**.:********.*:* ****::*******.*:******::**: .. . ", "identical_positions": 279, "similar_positions": 156, "identity": "43.8%" }, { "cls_id": "homologset.agr.MGI:1934765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7C7-1", "uniprot_id": "GPNMB_RAT", "id": "Q6P7C7-1", "name": "Transmembrane glycoprotein NMB", "aln": "MESLCGVLVFLLLAAGLPLQAAKRFRDVLGHEQYPDHMRENNQLRGWSSDENEWDEQLYPVWRRGEGRWKDSWEGGRVQAALTSDSPALVGSNITFVVNLVFPRCQKEDANGNIVYERNCRS------DLELASDPYVYNWTTGADDEDWEDSTSQGQHLRFPDGKPFPRPHGRKKWNFVYVFHTLGQYFQKLGRCSARVSINTVNLTVGPQVMEVIVFR-RHGRAYIPISKVKDVYVITDQIPIFVTMYQKNDRNSSDE-TFLRDLPIFFDVLIHDPSHFLN-YSAISYKWNFGDNTGLFVSNNHTLNHTYVLNGTFNFNLTVQTAVPGPCPSPTPS--PSSSTSPSPASSPSP------------------------------------------------TLSTPSPSLMPTGHKSMELSDISNENCRINRYGYFRATITIVDGILEVNIIQVADVP-IPTPQPDNSLMDFIVTCKGATPTEACTIISDPTCQIAQNRVCSPVA-VDELCLLSVRRAFNGSGTYCVNFTLGDDASLALTS----ALISIPGKDLGSPLRTVNGVLISIGCLAMFVTMVTILLYKKHKTYKPIGNCTRNVVKGKGLSVFLSHAKAPFSRGDREKDPLLQDKPWML--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P91-1", "uniprot_id": "GPNMB_MOUSE", "id": "Q99P91-1", "name": "Transmembrane glycoprotein NMB", "aln": "MESLCGVLGFLLLAAGLPLQAAKRFRDVLGHEQYPDHMREHNQLRGWSSDENEWDEHLYPVWRRGDGRWKDSWEGGRVQAVLTSDSPALVGSNITFVVNLVFPRCQKEDANGNIVYEKNCRN------DLGLTSDLHVYNWTAGADDGDWEDGTSRSQHLRFPDRRPFPRPHGWKKWSFVYVFHTLGQYFQKLGRCSARVSINTVNLTAGPQVMEVTVFR-RYGRAYIPISKVKDVYVITDQIPVFVTMSQKNDRNLSDE-IFLRDLPIVFDVLIHDPSHFLN-DSAISYKWNFGDNTGLFVSNNHTLNHTYVLNGTFNLNLTVQTAVPGPCPPPSPSTPPPPSTPPSPPPSPLP------------------------------------------------TLSTPSPSLMPTGYKSMELSDISNENCRINRYGYFRATITIVEGILEVSIMQIADVP-MPTPQPANSLMDFTVTCKGATPMEACTIISDPTCQIAQNRVCSPVA-VDGLCLLSVRRAFNGSGTYCVNFTLGDDASLALTS----TLISIPGKDPDSPLRAVNGVLISIGCLAVLVTMVTILLYKKHKAYKPIGNCPRNTVKGKGLSVLLSHAKAPFFRGDQEKDPLLQDKPRTL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14956-1", "uniprot_id": "GPNMB_HUMAN", "id": "Q14956-1", "name": "Transmembrane glycoprotein NMB", "aln": "MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNCRN------EAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTLGQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYR-RHGRAYVPIAQVKDVYVVTDQIPVFVTMFQKNDRNSSDE-TFLKDLPIMFDVLIHDPSHFLN-YSTINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNLTVKAAAPGPCPPPPPP--PRPSKPTPSLATTLK------------------------------------------------SYDSNTP--GPAGDNPLELSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVL-MPVPWPESSLIDFVVTCQGSIPTEVCTIISDPTCEITQNTVCSPVD-VDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS----TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKGLSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7J7-1", "uniprot_id": "E7F7J7_DANRE", "id": "E7F7J7-1", "name": "", "aln": "MMRLELLFVLAWAFFVPGTNSKKTYGDMFPHKHKLPFP---FPIPGWEPDTNPWDESLYPPFKPQLTRRHE----KPPKVRLTSDSPAMNGSCISFTAALEFPPCQKEDSNGNLVYDEHCDDGTMDTSANGQLRSGYVFNWTSWLDDYGYGKCTDLKRCNVFPDGKPFPQTNDWRRRGYVYVWHTMGQYFETCDGSSSHLTLNTTNMTFGADVMEVMVYRKRERRKYSPLSTDKSVYFITDKIPLSVNISQKEAASRADRNIFVRGSDVIFNVQLHDPSNYLKTADAVDFIWDFRDGN-QLVTHSSVATHAYDMLGNVTVKLLVEAAFRVPCPPPTPTPVHFTQAHTTAIPTLPPGTHTFTSKMETTKAPVISSALPMTTTRVPTTAIPTTEPFQTDSEVTATAPESSSSYNQPTAPPLLKHKHFQESDCFRHMYGSFEGEIILIERPPALQNLPANQILKVSADKVSNTSVNFMVTCSGSVPSVACTIVANSACREVKNIVCEDVTPYDEGCKISLTRIFQTPGTYCINITLGVPGGLALATTTSITIGNSPDKNSPKSPHVAEVVLSSSAVLICIFAFIAYMVYKRYKVYRPVRRSMLEDAERNTDSWGLGKLRAVLFSVDEERSCLLTEKPQ----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .: : :: * : *:: ::: . : **..* * *:* *** :: * :: :. *******: ** *:*.. * ** *****:***:**:.:* . . :*:***: :* . . *. : *** :***: . :: .::**:**:****:. . .* ::::**.*:* *.::*** *:* * * * *:: *.**.:**:**: *.: **: . :*. *::. :.*:* :****::*: .::.: *.* *.. :*: . . .*:* : *....:* *::* ***.*.*. .. ... .: : .: :. *:. :: . : :.:* : ** *.. * ::: :. : :: :.. .: ::* ***.*: * .***:::.:*. .:* **. * * * ::: * *: .****:*:*** .***:: :: . *.:: .. : .: .* * . * :.:.:: ::**::* *.*: .. : .. : * *.: :* : :.*:. ** :: ", "identical_positions": 158, "similar_positions": 215, "identity": "24.73%" }, { "cls_id": "homologset.agr.MGI:1934811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPJ0-1", "uniprot_id": "NUCKS_RAT", "id": "Q9EPJ0-1", "name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "aln": "MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEKDVKTKKDDSHSAEDSEDEKDDHKSVRQQRQAASKAASKQREMLLEDVGSEEEPEEDDEAPFQEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKTSKEKTPSPKEEDEEAESPPEKKTSASPPLEKSGDEGSEDEAASGED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XU3-1", "uniprot_id": "NUCKS_MOUSE", "id": "Q80XU3-1", "name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "aln": "MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEKDVKTKKDDSHSAEDSEDEKDDHKNVRQQRQAASKAASKQREMLLEDVGSEEEPEEDDEAPFQEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKAKVGRPTASKKSKEKTPSPKEEDEEAESPPEK---------KSGDEGSEDEASSGED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1E3-1", "uniprot_id": "NUCKS_HUMAN", "id": "Q9H1E3-1", "name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "aln": "MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPTKKIRSSPREAKNKRRSGKNSQEDSEDSEDKDVKTKKDDSHSAEDSEDEKEDHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPPEKKTSTSPPPEKSGDEGSEDEAPSGED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************************:****************************:********************:***.*******************:******** **:******************************************************************.********* **************.****** ***********.****", "identical_positions": 223, "similar_positions": 9, "identity": "91.77%" }, { "cls_id": "homologset.agr.MGI:1934816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8VPN2-1", "uniprot_id": "TEX15_MOUSE", "id": "F8VPN2-1", "name": "Testis-expressed protein 15", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTYFFIY---------------------------------------------VSTERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPFVQENCPCKALNSEMGPFSSDTSSSYGNVQNGNNSVLEAYNRQTENSSNLRDASQVYTHNSGFSFIPTGNTASGNGDLFS-VTYLRSILSSISAAFPSHNNTGSSTVITSKLIKDPRLMKREQSMRNKSDTAGLSDVLPLDKSLGCGDSQIKLTCMPTSSISSSEVPADNTITSCLNASCFKFSSESSHYQAHNSSSKGHDCIASSSIAVTEQFKEQHSSSFPSSLSNAFSDVRKQKHSEEQVQRAQMRSNVPVLTALSSESRNSDESEN---TCSNDSQGHFSQESPSSDINSIYKVGHQMSTVFPAQKKGNLCEYIQDTGMMRASISTEDSTKDGVNHTWCKET--VLSNETVSSPIDNSNTLYQEHKEGGNLNSLSGNCEKIGVTHKLQVPKFPISSTGDKNELYRAALELECSLTPTIECLSQKYPQHSLEHEDN--TNFAMTQGLIELKTVQNNQNFGNILSDAFQEAKDVPLASEKLIDRVISSAAIDISLDSSVCNIIGEYTCVRRENENGEASPYNCHK--EEASRVKDGVQDHSLSYDAELSCDLNLKINLQEQRDDKNPNEAK---------EHNTDNINGSEKQDCLANDHFTNIVEMREIKSNTEVEILNSEECFTFNSFRGK--NGKPAETASSESE-----AVEQRHAPNDQRGLEHLVS-SFPEIEGSSVCVASNATKQIVGTTVLTVSTSLGDHQKDELKEICSSESSDLG-LVKHSISECEIDTDKDKLQD-FHQLVNENSALKT-GLGSEIEVDL-EHDNASVFQQNMHSQGNDLCEEFEL-YESLKSRIDWEGLFGSSYEEIESSSFARRE-GTDQHSSTECNCVSFCSQ-DKRELHNPIFLPDLQVTITNLLSLRISPTDESLELKDNFYKQVTESTEPETNKE-GNASGFGMCSQPSGENSSFSCANKFGNSVQESGDVSKSESSHSSNSSHNTHVDQGSGKPNNDSLSTEPSNVTVMNDKSKCP-TKSKPVFNDTRNKKDMQSRSSKRTLHASSSRGQNIANKDLREHETHEKKRRPTSHGSSDRFSSLSQGRIKTFSQSEKHIRNVLNILNNEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGQKRKGPLPKAYAVIHNNFWESCDHQGDSLMSERRYS--KHFLSKRKYDKQGDKRFLRFDIEESLTPVSKHRLYRTNRERIAECLSNEVMSGHVS-SSLTTFHVREFCDEEQFPEPQLPLAYTSQSISQLEYTNSIVGN-ESSSELEHFSETSGNMLDP---KETLTEKEYQTHTQLCNSDS--AKLKNHTT-HSIRDIAKECNSEDKTVLCESNPVYLSFIKENTSHSPDKSYDSNCK----ANTDIHISVLGSKKKHILSVDIYEQDNCVSDGVKSGEAIFPIEKCTVPMETTSS-------IPTENIASKSYTIPPVSSILVTAGEEESS--------------------------------------VGENGLFDVNENEMNITMHSKLDLTSVTEESKICKKNMKNLSCNDSSMLLKENITGPS-KRYMAKYIEEEKIR-------KIEQAVYKKIITEGSPISFKYKSQNKILKEKSFHVNKKIITNNLTDSHLSIKNSTVDTIALK-DIPNQLKERKEAGQIKVNNNSHSD--------CLSKPAIVETNHRPVLHGNPKVATLQKELK-----------EHRSPNYTSHVTELSQILQRADEAASLQILEEETKLCQNILPLFVQAFERQQECSIDQILISRKLLVEQNLWNNCRLKLKPCAVDTWVELQMAMETIQFIENKKRFLEGKPTFRSLLWYDESLYSELLRRPRGYQLQSNFYPGFQGRLKYNAFCELQNYHNQLVEFLTETKKENNSYYALLKYKRQINECEAIMKHYSDCFDFCLSVPFACGVNFGDSLGDLETLRKSTLKLISVPGGSPKVHSYPGKKDHLWIIIEIVSSKVSFIKSNEEISIKICLYGLEHIYFDAAKSLVWKEKSCSLPKKHSEKNRE--MEEINERAFSKLKKIYDVLSKGLNNEPTS-IGLQEDAIIASKQS------TLGSISNCRLNKAWLSYPDISCVGEILDQAKSADLEELQGLTLRCTDHLEILKKYFQMLQEDNIDNIFIMEENVLDMLSNHNLGAVILKPEAIEIYIEIVMISETIHYLKNLIAKKLHNQRFRGMLWFDWSLLPELIGCQEEVVSLSVG--DTQTHCLWKLVETAISVLKKELAVIYEYGEASNCSYALHLFYRELKELTGVKRLLNNSKYSVSTYIDLVPHTASVNFGNTVAELEHNYKQFFLLLKNVMSVPQKDFGKMVHIIKVMKTIEHMKLLSAKDTKLSTHLLFLQMLRNKRNALQQNRQEKMETPVTEPGEDSSQPGVSEQTPPGTECTVKNISDSSKKRPVTADTCEVSQGKGNTDTVPSWKKQKVTMKDVGNI---QTVSKHPSTTGSPPNDENKIGSNSSDSLKSISASPEVVKRQSSVLGSVSPAESVQDTCTPKSESKVEPTDSLPDSLASLTEQQENSNVIEKRNGNSSVAETN-DKKDCP-LVTCDQKDIDASYSPDH-TPAQESHKTPVDHTQIS-PSNLTAGNDDPLVPDASLLSVSASQSEKDVY----LSGTDFHHENNKILNLSTEDCTGTSSPEPVCIKDKISVLQVDKTQPIKSESPKKSMTDAPNPNTAP-FGSYGNSALNVNGTVQHTHSEQ----NSKVLTQKVGTSRNIPPQSACSPVHNSSAHSFGTSYPYYSWCFYQYSSSNGTAVTHTYQGMTAYEIQQPPPPVLTTVASTVQSTHFNRSYSEHFSYFPGQPQANSFNPGNGYFPSHTPVSYNYQQPVYSQFASHQPVPQATYPYPPNPGAPPQVPWTYAPWQQNPFLRRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZYB8-1", "uniprot_id": "D3ZYB8_RAT", "id": "D3ZYB8-1", "name": "", "aln": "MTSIKMEMNENDKYRSPDGESLWTTDTDASSGKKFTIPKIRRTTEKVYLSSCYTNTREYGVIHGTLRQCRLDVSCDPQLTCQFGDTRLVRNEYLEKQFAAKRSEMRESGRNSRELEEHFCFLALPQSSVVDIYQNALSVGTSALRVLGNPLLGVYLFRHVDVALRYTLSRSSTVESIMVFKVLFGRVKKIQPSVDKNKVSLDPSPNFDCHMSRNMPSLKDSIELQAYNSMVYFYEYDLFSRPVDKPRQCLPYAIVTVKCVGQKAGNGQLMTSLRFPSTGFPKRLERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPFAQENCPCKALNSEMGPPSSDTPNSYGNAQNGNSFWLEPYNRERENSSQLRDGSQVYTHNSGFSFIPTDNTASGNDDLFS-VTYLRSILSSISATFPSHNNTVSSTVITSKLIKDPRLMKREQSMKNQNNTTGLSDVLPFDKSLGPGDSQM-LTCVPASSVSSCEVQADHTITNCLDASCFKFSSERSHCQTHSIGSQAYDCIASKRTAITEQFKEQHSSSFPGSLSNALSDVGKQEHSEEQAQRTQMRSNIPVLTALSNEPQNSYESEKSELTCSKDSRGHFSQE--SSNTDTIYKVDHQMSTVFPVQKEGNLCEYVQERRVMRTFISPEDGSKDGVEQTWSKET--VFTNEAISGTIDNSKTLYQEHKEGGNLNSLSGNCEKIAVTYKLQMPKLPMSSTGDNSELDRAASELEHSLIPNVECPSQKCAQHSLEHEDN--TKFAMAQGLIELKT----QNFGNILSDEFQEAKAVPLAREKLMDRGSPSSAIDISLDSSVRNMLGEYRCIQRGNENVTVSPFNCHK--AAAPHVNDNVQDHSLSYDAELSCDLNLKINLQEQRDDENPREAKEKEDAALSPEHSTDSMNGSEKPDFHANGLFTSIVEMRGIRSNTKIEIVNSEDCFTLHSFWGK--KGKAAETASSGSE-----GVGKRHAPGDERHREHLVS-ALPSTGGSSVCVASNATKQVVGTTVLTVSTNHGHHQKDQLKDTCSSETSDLG-LVKHSISECEIDADKDKLQD-FDQLMNENSALKDYGLGSEIEIDLEEHDNASLFQQNMHSHENDLCEECDF-YESLKSRIDWQGLFGKSYEEMETSSSARREEGAGQLCSTECNYVSFYSQKDKKGLHNPIFLPNLQVTITNLRSLRISPTDESLEPKDNFYRHITESTEPETNKE-GNASGFSICSQPSGENSSFSCENKFSNSVQESGNTSKSGITHSSNSSHNTPVDQGSGKPNSDSLSIDPSNITVMNDKSKYP-TKSKPDFSDARNKKDMKSRSSRRNMHASS-RGQNIAHKDLRDRETHERRRKPTSHDSSDRFSSLSQGRIKTFSQSERHIRNVLNILNSEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGQKRKGPLPKAYAIIRNNFWESCDLQGDSLMSERRYS--KHVLSKRKYDKQGEKKFLRFDIEESLTPVSKHRSYRTSRERVAECLSSEIMSGHAS-SSLTAFHVREFCDEEQLPESQLPLAYTSQSISQSEHTNSILGN-AGSSELEHFSKTSGNILDP---EETLTEKDYQTDTQLCNSDS--AKLENHST-HSIRNIAKEYNSEGKTGVCESNSVSLSFIKEKTSHSPDNSRGATCK----ANSDTHLSVLDANKNHILSVDIYEQDNRVYDGAKNGEAIFPTEKCSVPMETTSS-------IPTESLASRSYAVPPVPSVLTTAGEEESS--------------------------------------VGENELFDIDKSEIIITKRSKLDLTSVTEGSDNYKKNMNALSSSDNVVLLKQNVIGPS-KGYMAKYIEEEKIR-------KIEQAVYKKIITEGSAISFKYKSQNKLLKEESFPVNKKMMTNNLTDSHLSTKNPTVGTVASQ-TIPNQRKERMEAGQIKVSDSSRSD--------CLSQPAMGESSHRPALCENSKAAALKKEL------------EHRSANYTSHVTELPQILQRADEAASLQILEEETKLCQNILPLFVKAFERQQECSVDQILISRKLLVEQNLWNNCRLKLKPCAVDAWVELQMAMETIQFIENKKRFLEGKPTFRSLLWYDESLYSELLHRPRGYQLQSNFYPGFQGRLKYNAFCELQNYHNQLVEFLTETKKENNSYYAFLKYKRQINECEAIMKHYSDCFDFCLSVPFACGVNFGDSLGDLETLRKSTLKLISVHGGSPKVHSYPGKNDHLWIIIEIVSSKVSFIKSNEEINIKICLYGLEHIYFDAAKSLVWKEKSCSLLKAHSEKTRE--AEEINECAFSKLKKIYGVLSKGLNSEPTG-IGLEEDAMIASTQS------ALGSIPNCRLNKAWLSYPDISCVGDILDQAKSADLEKLQDLTLRCSDHLEILKKYFQMLQEDNIDNIFIMEENVSDMLNNHSPEAVILKPEAIEIYIEIVMVSETIHYLKNSIAKKLHNQRFRGMLWFDWSLLPELIGGQKEVASFSVG--DNQTHGLWKLIETAISVLKKELAIIYEYGEASNCSYALHLFYRELKELTGVKRLLSNAKYSVSTYIDLVPHTASVNFGNTAAELEQNYKQFFLLLKNVMSVPQKDFGKMVHIMKVMKTIEHMKVLNAKDTKLSTRLLFLQMLRNRRNALQQNGKGRKETSVTEPEEDSSQPAASEQTAPAAERTMKSISASSKKRPVTSDTCEVSQEEGDTDAVSSWKKQKVTVKDDGNS---QTISKHPSTAGAPPDNEDRTGSDSSDTLTGFSASPEVVKRRN----SVSPAESVQDTCTPKSASDVEPTDSSPDASASLTAQQEDSDGIKEGNVGFSAAETN-NKEDCP-LVTCDQKDIHSSSSPDH-TPAQKSHNTAVDHTQIA-PSNLTAGNDDPLVPDASLLSVSAPQAVKDIHSSPEMSDTDSQRENSEIVDLSTEDRTCTSSPELVCIQDKTPDLQVDKTQPIKSESPEKCAMDAPNPSAAP-FGSYGSSAINVNGTVQHTHSEW----NPKVLTQKFGTSRNRPPQPASPTVYNSSEHSFGASYPSYSWCFYQYSSSNGTAVTHTYQGVTAYEMQ-PPPPMLTPGASTVQGTHVNHSYSEHFSYASGQPQANSFIPGNGYYPSQAPVSYNYQQPVYSQFASHQPVPQAAYPYPPNPGAPP--PWTYAPWQQDPFPRRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXT5-1", "uniprot_id": "TEX15_HUMAN", "id": "Q9BXT5-1", "name": "Testis-expressed protein 15", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSDAKDSVNGDLLLNWTSLKNILSGLNASFPLHNNTGSSTVTTSKSIKDPRLMRREESMGEQSSTAGLNEVLQFEKSSDNVNSEIKSTPSNSASSSEVVPGDCAVLTNGLDTPCFKTSVNDSQSWAHNMGSEDYDCIPPNKVTMAGQCKDQGNFSFPISVSNVVSEVENQNHSEEKAQRAQQ------------ESGNAY---------TKEYSSHIFQDSQSSDLKTIYQTGCQTSTVFPLKKKVSIDEYLQNTGKMKNFADLEDSSKHEEKQTSWKEIDNDFTNETKISPIDNYIVLHQEYKESESHNSFGKSCDKILITQELEITKSSTSTIKDKDELD--HLALEWQITPSFESLSQKHPQHSVEYEGNIHTSLAIAQKLMELKLGKINQNYASIITEAFPKPKDIPQAKEMFIDTVISSYNIETAHDSSNCSITREHICVHRKNENEPVSLENIQRDYKETAYVEDRGQDHNLFCNSQLSNDIWLNVNFKKQTDRENQNEAK--ENSASCVENNIENIYGDKKQDSHTNENFSNIDEK-EDKNYHNIEILSSEEFSTKFNLICREDNAVSAATALLESEEDTISAVKQKDTENTGRSVEHLASTTFPKTASSSVCVASNAAIQIASATMPALSLNNDDHQIYQFKETCSSESPDFGLLVKHRVSDCEIDTDKNKSQESFHQSINENLVLQSIELESEIEIELEDCDDAFIFQQDTHSHENMLCEEFVTSYKALKSRISWEGLLALDNGEMEVLESTTGRENSDQHYSKESNYFYSSTQNNETELTSPILLPDLQIKITNIFRPGFSPTADSLALKDSFCTHVTEATKPEINKEDGEILGFDIYSQPFGENADYPCEDKVDNIRQESGPVSNSEISLSFDLSRNTDVNHTSENQNSESLFTEPSNVTTIDDGSRCFFTKSKTDYNDTKNKKEVESRISKRKLHISS-RDQNIPHKDLRRHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLNILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTSLQLITKVGEERKGPLPKSYAIICNNFWESCDLQGYSSVSQRKYYSTKHFSSKRKYDKRRKKRAPKADISKSLTHVSKHKSYKTSGE--KKCLSRKSMASSVSKSHPTTSHMGEFCN-QEHPESQLPVSSTSQSTSQSVYYNSSVSNPSLSEEHQPFSGKTAYLFSPDHSDEKLIEKENQIDTAFLSSTSKYEKLEKHSANHNVKDATKENSCDANEVINESNSVSLSCIKENINSSTGNDCDATCIGHTKAKTDVLISVLDSNVKHFLN-DLYQQGNLILSDCKRNLEVKWTDPIERPKQNIITGNFLMGPLNLTLIASKKYSIPQLSAAAVTDSEGESSKSYLDKQRILTVDSFAASSTVPHCEQSCREKELLKTEQCSSGNCLHTDGNETNVTENYELDVASGTEEDKSYGENIVELSSSDSSLLLKDNVKGSSSETCIVKKDTEDRITWKVKQAEKAKDSVYKRSMTEGSTVNTEYKNQKNQISEESC-LNEKIITTNLIDSHLSTKNTTTESVPLKNTVSNPLNKREKKGEIKVSKDSQSDLTLHSEIAYISKPGILGVNHTPILPAHSETCKVPTLLKKPASYVSDFKEKHCSANHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISRELLVDQNLWNNCKHTLKPCAVDTLVELQMMMETIQFIENKKRHLEGEPTLRSLLWYDETLYAELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVELLEETKREKNSYYVFLKYKRQVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLINVCGDSPKVHSYPGKQDHLWIIIEMISSKVNFIKNNEAVRVKISLYGLEHIFFDAAKNLVWKERTQSFSKKYSQKKDEERLLRVNKCAFSKLQKIYDTLSKDLNNEPISPIGLEEDTIIASRKSDHPINEATISIENSKFNSNLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQMLQDNNMDNIFITEENVLDVVINHSHEAIILKPEAIEMYIEIVMVSETIHFLKNSIAKKLDKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKDNSTDVCLWKVIETAVSELKKDLDIICKYNEAVNCSYAIHLLSRELQELSEIKKLLKKSKYFISTYIDFVPYIASINYGSTVTELEYNYNQFSTLLKNVMSAPRKDLGKMAHIRKVMKTIEHMKMICTKNAELTISFFLCQMLYNRRKILQLKRKEKMNIHIVKPGENNNKFSISTMLPPVSECINKNISNSSKKRPSTVDKCEDSQEQQQDTTVSSCKKLKVDMKDVTKINREKATFKHPRTTGSHPKSENKIVPSSCDSLKRNHLTPKKVEMQRSLPGSLLPLENPKDTCASKSESKIDLTVSS----DHFSGQQENLNSMKKRNVNFSAAETKSDKKDCAAFAICDQKSVHGTFSPDHGTLLQKFLKNSPDPTQKSCLSDINPETDVSLVPDASVLSKPIFCFVKDVHPDLEMNDTVFELQDNDIVNSSIKNSSCMTSPEPICIQNKIPTLQINKLQPTETESEDKYMKDTLNPNTVHTFGASGHITLNVNQGAEYSLSEQQNDKNSKVLMQNAATYWNELPQSACNPTYNSSEHLFGTSYPYSAWCVYQYSNSNGNAITQTYQGITSYEVQPSPSGLLTTVASTAQGTHSNLLYSQYFTYFAGEPQANGFVPVNGYFQSQIPAS-NFRQPIFSQYASHQPLPQATYPYLPNRFVPPEVPWVYAPWHQESFHPGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:. . * *.**: * *:.***.:.*:** **** **** *** *******:**:** ::..*:**.:** ::** . :*:: * ::* *. .:*. *::.*** * : *: :*. .*: :***... ::: * *:* . *** *:**..*:* :*:****:.**:* *. *: ::: .*: *: **: .:**:.. * ***** :*: .: **:*: *: . **.:*. ::* ** ::**: ..*** .*:**:**. . **:. .*:** :* :*::.* . *: *:.** ** .: *..*. *** .***:*:*.* *.:*::* *:*** **:..*::: * :.* :* * * ::* .* *: : *** .: *: *::* *** .* * :: :. *:* ***.* :::** *: *::*:::* * :* .*** *:. :.: *.:* * :* *:.* * :. ::**:.**: * .: : :. .* ** ** .* ::.: . * ***.* ::*. .*********: *:..:*: ::* . ..** ::*: ****:.*:* **** :*:****:**:* *: *.* :*** .*: * ****::* : *:* :***: **: * **** *::*****.*:**:. . *:* . : . .:.* *.*.* . :* :: * .**:**:**:.***: :*** :** **.* ::**:*:** *** *: **.: *** ***:.:.* :*..* **** .*:* : * : *:** *:: * : *.:** :***:*.::* *: ****. :.*::***:::** *:*.:* ** *.***.:**** :: : ::*: **:.**: ****************:**:.*****..******** *****:***:****************:***::*******:**:* ******** ** * :*:*:* **. *******: .*: : **.:*** ****: *:*. * :*** : *:. .* * *: *: ***: :: **.***:: **** ** : ** :.* *.* : ** .:. ::.* .*.* **: * .* : .* * **::*:: *.::: :** ..: : : ***.* ** ***: . *..:. .:.* *::* :***.:: :*:*. *:*:*.* : .. * . : : * :. : : :**:.*::* :.: .* .* *** ... :. : .* :* . :**::* ** .. :*: **..*. :***:*: *.* : :.* *::* * :::***: :****.:. :**.*:: :.*:* :*:*::*.** ***** **.*. ::. : :.* ::* : *:***...*:** :*:*.: .* * * :.:.. : . * :* *.*:*: :::*.*********:*****:****:* *******:****:****::******:***:*******: .*******: ***** ************.***:**:********:**:*** :***:* *********************.**:****:* ***:*:****.:******:*******:* ******.*****:********* *** *********.* *.**********:********::****.***.** : :**.*******:*****.*****:: *: * :*:*. * .:*: *****:***..***.**.** . ***:**::*** :* : ** *.::*. *::***.*:.:*****: ***::**.*****:**************::*:***** **** *:: **. *:********:******:*****:*** *****.:********** ******: *:::.*:*. :. ***::***:* ***:* :* :*.** *****:**: ***:**: :*:**.::** :*****:**: **:*:*.*.:*** **:** *******.*:**:***.** **********:: :*:::*: ::: *** *:*: ** : : : : :.:* *:..: . * .* :* *.** ****** * *.** ** : : :*.* ** ** :** : :: *** *:*: *..*:: ..*.*:*. :*: *: : *: * *. :***:.** *.:: * * :: ***: : ::: * . *.***: :*:**. :. ****.:..: **** * *: :.. * ** : *::.. .* .******:** . **:: :..* . ::..*:: * :: : :*** :**::* . **::* ** ::** .* *: **.:. **: * ::*** .::: ** *.*** *: .* * **.*. ..:*** * **:*** :**.****.***.*:*:****:*:**:* .*. :**. ***.*.** * **::*:* .*:****.* * ***: *: *.* *::**::**:*****:***:*** ** .** **.****:*:.* ", "identical_positions": 1263, "similar_positions": 805, "identity": "39.36%" }, { "cls_id": "homologset.agr.MGI:1934835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61089-1", "uniprot_id": "UBE2N_MOUSE", "id": "P61089-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61088-1", "uniprot_id": "UBE2N_HUMAN", "id": "P61088-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQX9-1", "uniprot_id": "UBE2N_RAT", "id": "Q9EQX9-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKSNEAQAIETARAWTRLYAMNNI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JXB2-1", "uniprot_id": "UE2NL_HUMAN", "id": "Q5JXB2-1", "name": "Putative ubiquitin-conjugating enzyme E2 N-like", "aln": "MAELPHRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGESKDSPFEGGTFKRELLLAEEYPMAAPKVRFMTKIYHPNVDKLERISLDILKDKWSPALQIRTVLLSIQALLNAPNPDDPLANDVVEQWKTNEAQAIETARAWTRLYAMNSI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35128-1", "uniprot_id": "UBE2N_DROME", "id": "P35128-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MSSLPRRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTG-PNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNIDRLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJS5-1", "uniprot_id": "Q9VJS5_DROME", "id": "Q9VJS5-1", "name": "UBC core domain-containing protein", "aln": "MAALTPRIIKETQRLLEDPVPGISATPDECNARYFHVLVTG-PKDSPFEGGNFKLELFLPEDYPMKAPKVRFLTKIFHPNIDRVGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAELWKVNERRAIQLARECTLKHAMQN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52490-1", "uniprot_id": "UBC13_YEAST", "id": "P52490-1", "name": "Ubiquitin-conjugating enzyme E2 13", "aln": "MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEG-PEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. ******::*: :*****.* *.: * ***:* : * .::**:*.* *: ** *.::*** ******:***:***:*:: **.**:** :*********:******** :***:*******.* * ** * ** * :* :. ", "identical_positions": 88, "similar_positions": 35, "identity": "57.14%" }, { "cls_id": "homologset.agr.MGI:1934852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXD1-1", "uniprot_id": "ACOX2_MOUSE", "id": "Q9QXD1-1", "name": "Peroxisomal acyl-coenzyme A oxidase 2", "aln": "MGNPGDRVSLGETWSREVHPDIDSERHSPSFSVERLTNILDGGIPNTELRRRVESLIQRDP-VFNLKHLYFMTRD-----------------ELYEDAVQKRFHLEKLAWSLGWSEDG------PERIYADRVLAGYNNLNLHG----------IAMNAIRSLGSDEQIAKWGQL--GKNFQ-IITTYAQTELGHGTYLQGLETEATYDATTQEFVIHSPTMTSIKWWPGDLGRTVTHAVVLAHLICLGARHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGFENIDNGFLRLNHVRVPRENMLSRFAEVL--PDGTYQRLGTPQSNYLG---MLVTRVQLLYKGFLPTLQKACTIAVRYAVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYALHFMTTSLLQFFHSSYSDILKR-----------DFSLLPELHALSTGMKAMSSDFCAQGTEICRRACGGHGYSKLSGLPTLVTQAIASCTYEGENTVLYLQVARFLMKSYLQAQVSPGSIPQKPLPQSVMYLATPRPARCPAQTAADFRCPEVYTTAWAYVSARLIRDATQHTQTLMRSGVDQYDAWNQTSVIHLQAAKAHCYFLTVRNFKEAVEKL----DNEPEIQRVLQNLCDLYALNGILTNSGDFLHDGF-LSGAQVDMARTAFLDLLPLIRKDAILLTDAFDFSDHCLNSALGCYDGHVYQRLFEWAQKS-PANTQ-ENPAYKKYIRPLMQSWKPKL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97562-1", "uniprot_id": "ACOX2_RAT", "id": "P97562-1", "name": "Peroxisomal acyl-coenzyme A oxidase 2", "aln": "MGSPMHRVSLGDHWSWQVHPDIDSERHSPSFSVERLTNILDGGLPNTVLRRKVESIIQSDP-VFNLKKLYFMTRE-----------------ELYEDAIQKRFHLEKLAWSLGWSEDG------PERIYANRVLDGNVNLSLHG----------VAMNAIRSLGSDEQIAKWGQL--CKNFQ-IITTYAQTELGHGTYLQGLETEATYDEARQELVIHSPTMTSTKWWPGDLGWSVTHAVVLAQLTCLGVRHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGLEHIDNGFLQLNHVRVPRENMLSRFAEVL--PDGTYQRLGTPQSNYLG---MLVTRVQLLCKGILPSLQKACIIATRYSVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYAFHFTATSLSEFFHSSYSAILKR-----------DFSLLPELHALSTGMKATFADFCAQGAEICRRACGGHGYSKLSGLPTLVARATASCTYEGENTVLYLQVARFLMKSYLQAQASPGATPQKPLPQSVMYIATQRPARCSAQTAADFRCPDVYTTAWAYVSTRLIRDAAHRTQTLMKSGVDQHDAWNQTTVIHLQAAKAHCYFITVKNFKEAVEKL----DKEPEIQRVLQRLCDLYALHGVLTNSGDFLHDGF-LSGAQVDMAREAFLDLLPLIRKDAILLTDAFDFSDHCLNSALGCYDGHVYERLFEWAQKY-PANTQ-ENPAYKKYIRPLMLGWRHKM------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99424-1", "uniprot_id": "ACOX2_HUMAN", "id": "Q99424-1", "name": "Peroxisomal acyl-coenzyme A oxidase 2", "aln": "MGSPVHRVSLGDTWSRQMHPDIESERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYP-EFSCKDNYFMTQN-----------------ERYKAAMRRAFHIRLIARRLGWLEDG------RELGYAYRALSGDVALNIHR----------VFVRALRSLGSEEQIAKWDPL--CKNIQ-IIATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHALVQAQLICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHVRVPRENMLSRFAQVL--PDGTYVKLGTAQSNYLP---MVVVRVELLSGEILPILQKACVIAMRYSVIRRQSRLRPSDPEAKVLDYQTQQQKLFPQLAISYAFHFLAVSLLEFFQHSYTAILNQ-----------DFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASCTYEGENTVLYLQVARFLVKSYLQTQMSPGSTPQRSLSPSVAYLTAPDLARCPAQRAADFLCPELYTTAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHLQAAKVHCYYVTVKGFTEALEKL----ENEPAIQQVLKRLCDLHAIHGILTNSGDFLHDAF-LSGAQVDMARTAYLDLLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKS-PTNTQ-ENPAYEEYIRPLLQSWRSKL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KML2-1", "uniprot_id": "ACOX1_DROME", "id": "Q7KML2-1", "name": "Acyl-coenzyme A oxidase 1", "aln": "------------MPAKPVNPDLQKERSTATFNPREFSVLWAGGEERFKEKKALEKLFLEDPALQDDLPISYLSHK-----------------ELYEHSLRKACIIGEKIRKLRADGED------GVDTYN-ALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQQVEWLSK--AWDCE-IIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTANHAVVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPLNNMLMKNQQVL--PDGTYVAPKNSVLTYGT---MMFVRCALIR-DTAQSLAKASTIATRYSAVRRQSPIDPNQPEPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQG-----------NLDRLPEMHALSCCLKAICSADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYGQALNG------EKLVPTVSYISDAINQTKFVNFDGSLRS---IVKAFQFVAANKTRIAYEQIELRRKQGYGTEVAANLCGTFLTAAADLHGRAFLAQTAYTELLA--LSREVSPELAEVLKVVLELYLVDACLNRIGDFLRFID-LTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDRVLDSALGAYDGNVYEHIFESTKKN-PLNKEPVNGAFHKYLKPFMKAHL---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2G9-1", "uniprot_id": "Q9W2G9_DROME", "id": "Q9W2G9-1", "name": "Acyl-coenzyme A oxidase", "aln": "------MASSTSVIPTTVNPDLQKERDAASFNSEEFAAWWAGGEEVLKFNRGVREYMEKDVDLSEMLQLQNKTHE-----------------EIIEFSTRGAIEGAKKLRRLQEERNP------GGDVYWPNLYDAQVMWGLVPGGNPFGVMYVMLVKALQAQCTPEQYEEFGKR--VELFE-ICGTYAQTELGHGTYLRGLETRADFDRKTDQFVLNTPNISSYKWWPGGLGHSSNHCLVMAQLYIDGDCKGPHMFFIQVRDEDTHEPLPGVHIGDIGKKMGFIGVNNGFLGLKNVRIPRTRMLMRHAQVK--ADGSYVSSPTNVLTYFA---MVRTRCVIAK-NNAVMLASAATIATRYSAVRRQSPINPNEREPQIMDHVTQQMKLFPEIATSVAYRKAGDYLWNLYDVTIEDIENG-----------KYERLPELHSLSCALKVTCSMDSASGVEKLRLACGGHGFLTSSNMSSIYVSATAACTYEGENTVLLLQIGRFLMKTWRAALTG------APLPPTVRYLAEVQKNPEFGTWTGSWEN---MVKAMQYAAANRTQLAFRSLSKRMSRGETEANAANHTGIEFTQAAELHGRAFVFSAFYEAVTGP-QSKTRSANFNRVLENLLELYLVKETLNQMGHLLRFIN-LTDTDLSGLQDRLETVLTKLRPDAVAIVDGFDFSDLQLNSTLGSYDGNAYERIFDAALKN-PMNQKAVPKYFHEILRPFMKSNI---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3U0-1", "uniprot_id": "Q9W3U0_DROME", "id": "Q9W3U0-1", "name": "Acyl-coenzyme A oxidase", "aln": "---------------MSVNADLQRERAAATLDSEDFARWWAGGSGQLEERRALERRFYEDPDFAEPVHPSCLSYK-----------------ERYEQTVARSTRFLAKLRQWQREKQPQLQLSVNMLRDFRLLLSGSLGTGLFQQSFPLRVHFSMFMTTLLSQGTEEQQAQWLNR--SWHMDGVLGTYAQTELGHGTFVRGLETRADYDPITQEFILNTPTQSSYKWWPGGLGNTANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHEPLTGVDVGDIGPRLGGNGVNNGFLGLRDVRIPRNQMLMKNAQVL--TDGTFVQGRPPLLLYGT---MVYVRVITVK-DVLFGLLQAATIATRYSVVRRQSRINSDQPEVSVLDHITQQAKILPQIARGVSYRLVSDWLWRFYEDVLRQLEDEST--------KGRNSLPELHALSCCLKAVATDEASEGVDLLRKSCGGHGFLSSANFDSIYGLTAATYTYEGEYTVLLLQTARFLVRQYADSLKR------KVLPSSVSYLRDTAR---LIWGKNLVAN---CVRALEISAMEQVRDAWQTQKMHQSGKVSPEMASNLAGRQLTSAAIAHAHAFFTRNALEQVEALRKKGDLSPNVSLILGQLVELFVIDTFLRQSGCVLRWNNGITGTQLRFVERRFEELLAKLRPNAVALVDGFDFHDRVLGSTLGCHDGRVYERLMEEARRN-PINQEPVNSSFHNHLLPMMRGKL---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13711-1", "uniprot_id": "ACOX_YEAST", "id": "P13711-1", "name": "Acyl-coenzyme A oxidase", "aln": "--MTRRTTINPDSVVLNPQKFIQKERADSKIKVDQVNTFLESSPERRTLTHALIDQIVNDPILKTDTDYYDAKKMQEREITAKKIARLASYMEHDIKTVRKHFRDTDLMKELQANDPDKASPLTNKDLFIFDKRLSLVANIDPQLGTRVGVHLGLFGNCIKGNGTDEQIRYWLQERGATLMKGIYGCFAMTELGHGSNVAQLQTRAVYDKQNDTFVIDTPDLTATKWWIGGAAHSATHAAVYARLIVEGKDYGVKTFVVPLRDPSTFQLLAGVSIGDIGAKMGRDGIDNGWIQFRNVVIPREFMLSRFTKVVRSPDGSVTVKTEPQLDQISGYSALLSGRVNMVMDSFRFGSKFATIAVRYAVGRQQFAPRKGLSETQLIDYPLHQYRVLPQLCVPYLVSPVAFKLMDNYYSTLDELYNASSSAYKAALVTVSKKLKNLFIDSASLKATNTWLIATLIDELRQTCGGHGYSQYNGFGKGYDDWVVQCTWEGDNNVLSLTSAKSILKKFIDSATKGRFDNTLDVDSFSYLKPQYIGSVVSGEIKSGLKELGDYTEIWSITLIKLLAHIGTLVEKSR--------SIDSVSKLLVLVSKFHALRCMLKTYYDKLNSR-DSHISDEITKESMWNVYKLFSLYFIDKHSGEFQQFKIFTPDQISKVVQPQLLALLPIVRKDCIGLTDSFELPDAMLNSPIGYFDGDIYHNYFNEVCRNNPVEADGAGKPSYHALLSSMLGRGFEFDQKLGGAANAEILSKINK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: ** .:. . .. : : : . * : . : : . : :* : . : :* ******: : *:*.* :* : :::.:* :: *** *. . : . . * *:* * * *.: :*. . :.*: :**** ::. :**:: :..* :* ** : :* .**: : . . ** **:. *:* . * .:::: :* :::*::. : : : . . * ::. * :*. : : : * :*****: .: . . *:**: .*: * .: ::: : : : . . . : : .: * : . : : .*. : . * . : .. . * .* :.: :.*.*:: * *.*.:* .** *.. :: . : * : . . : . : . ", "identical_positions": 79, "similar_positions": 162, "identity": "10.41%" }, { "cls_id": "homologset.agr.MGI:1934858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1H2A2-1", "uniprot_id": "B1H2A2_RAT", "id": "B1H2A2-1", "name": "Fibronectin type III and SPRY domain-containing protein 1", "aln": "MEDQREALRKIVTTLAMKNEETQTFIYSLKQMLLNVEANSAKVQEDLEAEFQSLTSVLEELRESMLMKIKQERASRTYELQNQLTACTRALESSEELLETANQTLQAADREDFPQAAKQIKDGVTMAPAFRLSLKAKVSDNMSHLMVDFTQERQMLQALKFLPVPSAPIINLAESLVADNCVTLVWHMPEEDSKIDHYVLEYRRTNFEGPPRLKEDHPWMVVEGIRHTECTLTGLKFDMKYMNVRVKACNKAVAGEFSEPVTLETPAFMFRLDGSTSHQNLRVEGLSVEWDAMGGKVQDIKAREKEGKGRTASPVNSPAR-GTPSPKRTASGRGGRDRFTAESYTVLGDTPIDSGEHYWEVRFEPDSKAFGLGVAYRSLGRFEQLGKTAASWCLHANNWLQASFTAKHANKVKVLDSPVPDCLGVHCDFHQGLLSFYNARTKQLLHTFKTKFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQKRGSATSSSNTSLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPM6-1", "uniprot_id": "FSD1_MOUSE", "id": "Q7TPM6-1", "name": "Fibronectin type III and SPRY domain-containing protein 1", "aln": "MEDQREALRKIITTLAMKNEETQTFIYSLKQMLLNVEANSAKVQEDLEAEFQSLTSVLEELKESMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQASDSEDFSQAAKEIKDGITMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPTIDLAESLVSDNCVTLVWHMPDEDSKIDHYVLEYRKTNFEGPPRLKEDHPWMVVEGIRQTEHTLTGLKFDMKYMNIRVKACNKAVAGEFSEPVTLETPAFMFRLDGSTSHQNLRVEDLSAEWDAMGGKVQDIKAREKEGKGRTASPVNSPAR-GTPSPKRMSSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRFEPDSKAFGLGVAYRSLGRFEQLGKTAASWCLHANNWLQASFTAKHANKVKVLDSPVPDCLGVHCDFHQGLLSFYNARTKQLLHTFKAKFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQKRGSATSSSNTSLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTV5-1", "uniprot_id": "FSD1_HUMAN", "id": "Q9BTV5-1", "name": "Fibronectin type III and SPRY domain-containing protein 1", "aln": "MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADNCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKAREKDGKGRTASPINSPAR-GTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQKRGSATSSSNTSLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY10-1", "uniprot_id": "FSD1_DANRE", "id": "Q1LY10-1", "name": "Fibronectin type III and SPRY domain-containing protein 1", "aln": "MDDQKESLRKIITTLALKNEEIQNFICSLKQSLENLEANSNRVQEDLESEFSSLHSVLDDLKEGMVTRIKQERASRTYELQSQLGACTKALESSEELLEFANQTLCSSENDSFTQAAKDIKDSVTMAPAFRLSLKAKASDSMNHMMVDFTHERNLLQSITFLPVPATPEIHVADCQVFDNTVTVVWTLPEPDSKIDHYILEHRKTNHEGPPRAREDYPWMVVEGIKETEYTLTGVRFDTRYMTFRVKACNKAVAGEFSEPVTLETHAFVFKLDASSSHQNLKVEDLSVEWDSSGGKVAVQDIRKE--KNRTNSPMHSPARTAMMSPKRAPSARVGRDRFTAESYTVLGDTMIDAGQHYWEVRFDKESKAFAAGVALRSLGRFDQLGKSNASWCIHLNNWLQQSLTAKHNNKARTLDCSIPDRIGIYCNYEEGTLSFYNSRNKTLLHTFRTKFQQPVIPAFMVWNGSFSVQTGLQVPSIVLSGQKRNSNTSSSNASLT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 326, "similar_positions": 116, "identity": "65.59%" }, { "cls_id": "homologset.agr.MGI:1934860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q562C6-1", "uniprot_id": "LZTL1_RAT", "id": "Q562C6-1", "name": "Leucine zipper transcription factor-like protein 1", "aln": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTIDEVSEVLNGLQAVVHSEVESELINTAHTNVLLLRQLFSQAEKWYLKLQTDVSELENRELLEQVAEFEKAEFASSNKKPIIDITKPKLVPINEGGTTELLNKEILRLQQENEKLKSRLKTIETQAVNALDEKSKLERVLQDLQLDQGNQQDFIKAQDLDDLENTVAALKSEFQKTLNDKTENQKSLEENLAAAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYESED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHQ5-1", "uniprot_id": "LZTL1_MOUSE", "id": "Q9JHQ5-1", "name": "Leucine zipper transcription factor-like protein 1", "aln": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKDSRLVEETFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFVSSSKKPIIDITKPKLVPINEGGTTELLNKEILRLQQENEKLKSRLKTIEIQAVNALDEKSKLERVLQDLQLDQENQQDLLKAQDLDDLENTVATLRSEFQKTLNDKTENQKSLEENLAAAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYESED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ48-1", "uniprot_id": "LZTL1_HUMAN", "id": "Q9NQ48-1", "name": "Leucine zipper transcription factor-like protein 1", "aln": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************************:*****:******************************:**********:************:*******************:.**.****:*:*****.*:*****:***********:************* **.**********:.******** **:*::*****.:******:*:**********************:************ **************************************:**.**", "identical_positions": 269, "similar_positions": 27, "identity": "89.97%" }, { "cls_id": "homologset.agr.MGI:1934919", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LIG8-1", "uniprot_id": "A0ABK0LIG8_RAT", "id": "A0ABK0LIG8-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MTAGLGWRGVAHCVPATVRPRTHPQPLGREWVRGLLPVAAARQQDGGSGPRSGGDNGVRKVTPAGAGSRPVRAGTRSPRSRRQARLILCGVGWPSLKFPMTQWTPEYNELYTLKVAMKSGTPPDAPTTQESLKAVLLHPQPLGATKSFPAEVEMINSKVGNEFS-HLCDDSQKQEKDMNDNQQEQEKSGVVRKKRKSQQAGPSYVQN-CVKENQEILGLRQH----LATPSDEDD--DSSFSECLSSPSSSLHFGDSDTVTSDED-KEVSVRHSQPILSAKS-------------------RSHNARSHKWPRTEAEPVPGLLMKRPCFHGSAVRRVPCRKRPVKSSS---SQRTQKQKERLLVQRKK---LAQRKYALLASSSTSSENDLSSDSSSSSSTDGEEDLCASASENP---SNPAAPSGSIDEDVVVIEASFTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHTGRAQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMDSQTTSASINNSNPSTSEQGSDTTSTVASSQPSTVSETAATLTSNSATGSSVGDDVRRTAS------NAVPESGPPAMPRLPSCCPQHSPCGGTSQSHHALAHPHSSCFQ--------------QHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERP-QVQAPCGANSSSGSSYHDQQALPVDLSNSALRTHGSG--GFHGASAFDPCCPVSSSRAAVFGHQAAAAP-TQPLS-IDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRALHHQAS-ACHHSHGSAPPQTQPPPQVDYVIPHPVHAFHSQISTHAASHPVAPPPP-----THLGSTAAPIPQHLPPAHQPISHHIPAPAP-SAQRLHPHEVMQRMEVQRRRLMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERTAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKK-----------------------------RKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ML9-1", "uniprot_id": "RN111_MOUSE", "id": "Q99ML9-1", "name": "E3 ubiquitin-protein ligase Arkadia", "aln": "---------------------------------------------------------------------------------------------------MSQWTPEFNELYTLKVAMKSGTP-DAPTTQESLKAVLLHPQPLGATKSFPAEVEMINSKVGNEFS-HLCDDSQKQEKDMTGNQQEQEKSGVVRKKRKSQQAGPSYVQN-CVKENQEILGRRQQ----LETPSDEDN--DSSLSECLSSPSSSLHFGGSDTVTSDED-KEVSVRHTQPVLSAKS-------------------RSHSARSHKWPRTEADPVPSLLMKRPCFHGSALRRVTCRKRLVKSSS---SQRTQKQKERMLVQRKKREALAQRKYALLSSSSSSSENDLSSDSSSSSSTDGEEDLCASASENP---SNPAAPSGSIDEDVVVIEASFTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHTGRPQESRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTIVPTTSARMDSQTTSASINNSNPSTSEQASDTTSTVASSQPSTVSETEATLTSNSATGSSVGDDVRRTAS------SAVPESGPPAMPRLPSCCPQHSPCGGTSQSHHALAHPHSSCFQ--------------QHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERP-QVQAPCGANSSSGSSYHDQQALPVDLSNSALRTHGSG--GFHGASAFDPCCPVTSSRAAVFGHQAAAAP-TQPLS-IDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQAS-ACHHSHGNAPPQTQPPPQVDYVIPHPVHAFHSQISSHAASHPVAPPPP-----THLGSTAAPIPQHLPPAHQPISHHIPAPAP-SAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERTAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGASFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKVTTD---------------------WFSQRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNA4-1", "uniprot_id": "RN111_HUMAN", "id": "Q6ZNA4-1", "name": "E3 ubiquitin-protein ligase Arkadia", "aln": "---------------------------------------------------------------------------------------------------MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFS-HLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQN-CVKENQGILGLRQH----LGTPSDEDN--DSSFSDCLSSPSSSLHFGDSDTVTSDED-KEVSVRHSQTILNAKS-------------------RSHSARSHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNS---SQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQ--NNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTS------SAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQ--------------QHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSG--SFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQAS-ACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPP-----THLASTAAPIPQHLPPTHQPISHHIPATAP-PAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKVTTD---------------------WFSQRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BG80-1", "uniprot_id": "A0A8M2BG80_DANRE", "id": "A0A8M2BG80-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--------------------------------------------------------------------------------------------------------------------MKSEISADARRKQEPLKGPLANPEPMETAKSFPAEMEVIG-KAGSDFTSPLCAETRHRPSRDAGGRRDCDRGLSGRKKRKSQQPGPSYCSLKEAPMSEATLTPPRHRPMLLETRSEDERNPESSLSDCASSPSSSLRFGDSDTLSSDEDGMPMTVRQQLKAHGAASTGSTGSSTGTAVGIRPLLARTRASRSHKWARLEPDSN---HVKRPCLGS---RRPLHRKRFVKGGAGGVTQRTPKQKERLLLQRKKREVIARKKYALLHSTSSSSE-EMTSDDSSPSSTEAEHELYVDVNSSSSQASTAAVASGVLDEDVVVIEATPAPAVPASEEINVTSTDSEVEIVTVGDAFRPRSVGGHGRMHWG--PSCSQSRAQEGRGRHRLSTVIQPLRQSAGEVVDLTVDEDDLSVVPTTSDSTHPQPVSSSSSSSSRNACTSASPQEGPGPSS-SCSAAAPDSTLAAQSHGGVPRSGTTNTTATEDESRRSLLGENGGVAMPRLPSCCPQHSPCSGPSSGHLSMGHTHSGCMQSGATQQSGPPQPGSQHSHTHSHHFHHHHHTAP-VPSSLAYQESSCPLERPTAMPAPCGGVSN---QYHDQQTLPVDLSSSAVRSSGSSSTGFHGTSAFDPCCPGSASRPPVYVSQAAPGPSQQTVA--DSFSPTIVAQPQPQPP---QLSSCRHYMHPTYGSLSRPLHHQSSSSCPHSHSNAPPPQQPPPQGDYVIPHPVLPFHTPLPTHAPGHTVPTAPPPSLPSHHLPGSSAPLPQHLPPEHQALQHHLPVLGPNSVQRLHHHDLLQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSLPRQSDQRTTWELGIEAGVTVAPYPSGHLHPHLPHYHPPPRLHHFPIQLMHTGSMPEVTYPHIRYISS-------RMTFGRTYEDLLHLEERLGTVNRGASQGTIERCTYPHKYKKKVVERDTEEQLAPEAWASVGKKMHSTSNSRKLHGKQEEEEGAEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQLCVDQWLLTNKKCPICRVDIEAQLSSES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** . ** .**.**. * :*:*: ::***** :*:*. *.*.:*: ** ::::: . ..::: ::. ********.**** . . .: * :: * * *::: :**:*:* *******:**.***::**** ::**: .* * *:: :*****.* *.:. :****: . ** *** **..: :*** *****:*:**** :*::***** *:*:*** :::*:.**.***:.*.:* ...... ...*..** :*********: :* *.*.******************:::*.**. **.* **. .*. .*.** *.* *:*********.*.**********: ::***** ..*..*:* ..*. .:. ..* .. .** ..:.: . :**:::* * . .. . *:: . : *.* ***************.*.*..* ::.*.*:.*:* **.* ..**.**** . * ** * ::.:.:**:*** : ****. *. .**:**:******.*.:*: **. .***:******** ::**..:: ***... *.:: *.:..::********* .******** *.*.**:*.****:* :* ***...** ***** ******** .**: :.:**..*.*...** ** .::**:****** **.:.**:*. .* ..**** *:::*********:************************************ ***: :*::**********.*.*..* *****.***.******: : : . ********* * .* .:*:*:*******.********************* **** **: ***:********************************:******:****************.***", "identical_positions": 537, "similar_positions": 267, "identity": "45.66%" }, { "cls_id": "homologset.agr.MGI:1934923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88728-1", "uniprot_id": "IFM5_MOUSE", "id": "O88728-1", "name": "Interferon-induced transmembrane protein 5", "aln": "MDTSYPREDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALVHSVKARDQKMAGNLEAARQYGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLSKLAKDSAAFFSTKFDEEDYN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7W9-1", "uniprot_id": "G3V7W9_RAT", "id": "G3V7W9-1", "name": "", "aln": "MDTSYPREDPRAPSSRKADAAAHTALSVGTPGPTPRDHMLWSVFSTLYLNLCCLGFLALVHSVKARDKKVAGDLEAAKQYGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLSRLAKDSAAFFSTKFDEEDYN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNB3-1", "uniprot_id": "IFM5_HUMAN", "id": "A6NNB3-1", "name": "Interferon-induced transmembrane protein 5", "aln": "MDTAYPREDTRAPTPSKAG--AHTALTLGAPHPPPRDHLIWSVFSTLYLNLCCLGFLALAYSIKARDQKVVGDLEAARRFGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLARLAKDSAAFFSTKFDDADYD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*****.***:. **. *****::*:* *.****::******:************.:*:****:*:.*:****:::*********************************::**************: **:", "identical_positions": 103, "similar_positions": 26, "identity": "76.87%" }, { "cls_id": "homologset.agr.MGI:1934928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B4F7B7-1", "uniprot_id": "DUS15_RAT", "id": "B4F7B7-1", "name": "Dual specificity protein phosphatase 15", "aln": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIVSIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTVVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFG--------------------------------------------------------------EIPFRDEE----DLRALLPLCRRCRQGPGTSAPSA------------------------TTASSAASEGTLQR-------------------LVPRSPRESHRP------------LPLLARVKQTFFCLPRCLSRKGGK------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4V2-1", "uniprot_id": "DUS15_MOUSE", "id": "Q8R4V2-1", "name": "Dual specificity protein phosphatase 15", "aln": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTIVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFG--------------------------------------------------------------EIPFRDEE----DLRALLPLCRRCRQGSATSAASA------------------------TTASSAA-EGTLQR-------------------LVPRSPRDSHQP------------LPLLARVKQTFFCLPRCLSRKGGK------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1R2-1", "uniprot_id": "DUS15_HUMAN", "id": "Q9H1R2-1", "name": "Dual specificity protein phosphatase 15", "aln": "MTEG---VLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSG------------------------------------------------------------AQCPPMTSATCLLAARVALLSAALVREATGRTAQRC------------------------RLSPRAAAERLLGPPPHVAAGWSPDPKYQICLCFGEEDPGPTQHPKEQL----IMADVQVQLRPGSSSCTLSASTERPDGS-----STPGNPDGITHLQCSCLHPKRAASSSCTR--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWL2-1", "uniprot_id": "DS22A_DANRE", "id": "Q1LWL2-1", "name": "Dual specificity protein phosphatase 22-A", "aln": "MGNGMNKVIDGLYLGNIRDSENRDSLSRNGITHILSVCNNAKPVLEDMTYLCINAADASSQNLSQHFKESIRFIHECRLNGGACLVHCLAGVSRSTTVVVAYLMTVTSYGWQECLTAVKAVRSFVGPNYGFQQQLQEFQMKQVSEYQAWLRASYR--------------------------------------------------------------SSPFKDQE----QVEALLSLFAEQQQ-----------------------------------------------------------------------QGQQNDP--------------EWMSQGSRIYPLSYNQYSASGS-----NR-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PI51-1", "uniprot_id": "M9PI51_DROME", "id": "M9PI51-1", "name": "Dual specificity protein phosphatase 15", "aln": "MNWHMGKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLSEERRRLRERFPSSALEQLDRTKVATALDNYQELLQNRDICEGNCSRGEKCPTGVCNMDPTKGLFRRRPSNASTHSRLRAQSSNANASSSSLSVSSAAAQSCPTSPKNSPLPIVRRSVGNERIPEDEIVLEQPPTTSREAAEYAAAFEDARREQEQRQLQQQQQLSRSQRSPRPVNSSREAPRVSSAGSRRESAAREGNGSAQLQRSASTVSGFGVRPRSSPAGLHAYTGSVPSSVHGSRVDLRDADKGSAIYLGCSAPRASTLSISSSRGSSGGSAPPSPCHTPPASPRHGVKRSTSLVKKPR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: ***:** *::: .* * *:**::: :..: :* * ** : .:*:.. :.::*. . *** .**. * *:**:**:***.*:. **:**.* .*:: * .::* *....** **:.**:** . .: . * : : . . * .* ", "identical_positions": 54, "similar_positions": 59, "identity": "12.08%" }, { "cls_id": "homologset.agr.MGI:1934943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFK9-1", "uniprot_id": "D3ZFK9_RAT", "id": "D3ZFK9-1", "name": "Protein amnionless", "aln": "MGALGR-VLLWLQLCALTRAAYKLWVPNTSFDTASNWNQNRTPCAGDAVQFPADKMVSVLVRDSHAISDMLLPLNGEFVLASGAAFSAAGGDSDPACNPGAPLLFRNPDRFSWLDPHLWSSGT------QESGIFFVDAERVPCTYDDVLFPRNGSFRVALGPGPNPVHVRSVSAVGQTFTRDEDLAAFLASREGRLRFHGSGALRVGSQACTDATGCVCGNAETLPWICASLLQPLGGRCPEATCQDPVRPQGQCCDLCGAIVSLTHDPTFDLER--YRARLLDLFLKQPQYQGLQVAVSKV----------LRDAHTEIQVVLLETRP---ATGAAGQLGHALLQDAVAQGSVLGIVSATLRQSGKPTAANSALDQNGSGAG-------LAGGVAAVVLLALVGTVLL--LLHRSGRLRWRRH------------GDAEPTSAGLPLG------------------------FRNPIFDVM-VFKQQQASVEFADSTQKVDILDID-TNFGCFVN-----PLFAGEAEAEA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JB7-1", "uniprot_id": "AMNLS_MOUSE", "id": "Q99JB7-1", "name": "Protein amnionless", "aln": "MGALGR-VLLWLQLCAMTRAAYKLWVPNTSFDTASNWNQNRTPCAGDAVQFPADKMVSVLVRDSHAISDMLLPLDGELVLASGAALSAAGGDSDPACNPGAPLLFRNPDRFSWLDPHLWSSGT------QAPGLFSVDAERVPCSYDDVLFPRDGSFRVALGPGPNPVHVRSVSAVGQTFSRDEDLTAFLASREGRLRFHGSGALRVGSQACTDASGCVCGNAEMLPWICASLLQPLGGRCPQAACQDPLLPQGQCCDLCGAIVSLTHDPTFDLER--YRARLLDLFLKQPQYQGLQVAVSKV----------LRDAHTEIQVVLVETEH---ATGAAGQLGHALLQDAVAQGSVLGIVSATLRQSGKPMTADSELNQSSSGAG-------LAGGVAALVLLALLGTVLL--LLHRSGRLRWRRH------------EDAEPVSAGLPLG------------------------FRNPIFDAI-VFKQQ-PSVELPDSAQKVDILDID-TKFGCFVN-----PLFAGEAEAEA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXJ7-1", "uniprot_id": "AMNLS_HUMAN", "id": "Q9BXJ7-1", "name": "Protein amnionless", "aln": "MGVLGR-VLLWLQLCALTQAVSKLWVPNTDFDVAANWSQNRTPCAGGAVEFPADKMVSVLVQEGHAVSDMLLPLDGELVLASGAGFGVSDVGSHLDCGAGEPAVFRDSDRFSWHDPHLWRSGD------EAPGLFFVDAERVPCRHDDVFFPPSASFRVGLGPGASPVRVRSISALGRTFTRDEDLAVFLASRAGRLRFHGPGALSVGPEDCADPSGCVCGNAEAQPWICAALLQPLGGRCPQAACHSALRPQGQCCDLCGAVVLLTHGPAFDLER--YRARILDTFLGLPQYHGLQVAVSKVPRSS-----RLREADTEIQVVLVENGP---ETGGAGRLARALLADVAENGEALGVLEATMRESGAHVWG-------SSAAG-------LAGGVAAAVLLALLVLLVAPPLLRRAGRLRWRRH------------EAAAP--AGAPLG------------------------FRNPVFDVT-ASEEL----PLPRRLSLVPKAAADSTSHSYFVN-----PLFAG-AEAEA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAN8-1", "uniprot_id": "A0A8M9QAN8_DANRE", "id": "A0A8M9QAN8-1", "name": "Protein amnionless", "aln": "MMALGHNVLLFFCISPFANALYKQWIPDTNFENATNWDKGSVPCGNDQVEFLANRKVSVYVETAHTITGMSLPVDGELILASGAGFTVREGG-DPGCGSGVTAQFKDSESLKWFDPSLWVAATTIDDLHRGTFQFSVHEESVPCQNDDVVFRDATSFRVEISS-DHDVPVKSVSVLGKKFTSSSEFSQYLSSSSGKLQFHGTATISISSSGCGEISGCICDNSRNREKICAN------VRCDTLECKKPLHALGHCCNVCGALVYVQFSSSFNFES--YRQRLQHLFLNTDKYRSVQMAMSKVSREQRLLGVIPFGATQEIQVLLLDQKTGLESGNLAETLARDIMKDVHNHGSNVGISSAEFQASSGASSSDVAGNSAGVVAGAVLGCLVILGLLAGFILLYRRGVVKLPRMPSIPSLSKWRNG------------SDIGELGGPMDHG------------------------FDNPMFDKP-TMMPEQPELYGSETMNSVVLTKSG----VHFVN-----PVYDETDFNG------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPN2-1", "uniprot_id": "AMNLS_DROME", "id": "Q9VPN2-1", "name": "Protein amnionless", "aln": "-MGLHWQWLIWALVGLHVALATKWYGGGMDFNDPTAWLDDHLPCAQDLVVFPEYYPALLPLPEDISIDGLVFPREGAILLAEESTITFGSDKQPSCESDENKAYLKPPKSSKWFDPGTWTDKS------KEFSTFTPELERIPCDDEQVIIKGHGPLAFDLEN-VQYLRLGQLILAGSSISKT-YLEQLISRDLGQFLFYNAEYVQVEYY-RGELCGCHKDFERLLEPVCHN----VQEQCETPHCLSPVRPLGSCCLICGAILSTPTTHCTEGSRKELVAQISNLISQESLKDQIGLHVEFVG---------SQKFGNCLQAVVTDRHK---YSERSLEFLQQNEHNWNKTGTTLKVSGRPYNPN-VSFSSIVLILFCMALVG------LVSVVILAHFMPENPYLNRIPQWIHDPRLWRWRHLGLRLRRNLLFNRFDNGGAEGGSSEGGASGVDRLGIMAYDPESGEVRERAFDNPMFEQGGALEEAAKESQEQDEILSVPKMETGDLDARSVVDEQELTEINLETCEADTDEETI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:: : . * : . .*: .: * .. **. . * * . : : :: .: :* :* ::**. : : . :: .. .* ** * . * . * :** ::*.: .: . : : : .: * .:: : :: *:: *:.. : : : ** . . :* :* * ..: . * ** :***:: : . :: . : : : :. * :*.:: : : : : : * : : . . . .* : : . .: . :**. . * * **:*: . * . .*: : ", "identical_positions": 49, "similar_positions": 115, "identity": "9.11%" }, { "cls_id": "homologset.agr.MGI:1934950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BK63-1", "uniprot_id": "KC1A_MOUSE", "id": "Q8BK63-1", "name": "Casein kinase I isoform alpha", "aln": "---MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTML----------------------------------------------------------------------------------------------------KQKAAQQAASSSG-----------------------QGQQAQTPTGKQTDKTKSNMKGF------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48729-1", "uniprot_id": "KC1A_HUMAN", "id": "P48729-1", "name": "Casein kinase I isoform alpha", "aln": "---MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTML----------------------------------------------------------------------------------------------------KQKAAQQAASSSG-----------------------QGQQAQTPTGKQTDKTKSNMKGF------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97633-1", "uniprot_id": "KC1A_RAT", "id": "P97633-1", "name": "Casein kinase I isoform alpha", "aln": "---MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQGKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTML----------------------------------------------------------------------------------------------------KQKAAQQAASSSG-----------------------QGQQAQTPT------------GF------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54367-1", "uniprot_id": "KC1A_DROME", "id": "P54367-1", "name": "Casein kinase I isoform alpha", "aln": "MDKMRILKESRPEIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTML----------------------------------------------------------------------------------------------------KQKTHQGQPNPAI-----------------------LLEQLDKDKEKQNGKPLIAD---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29295-1", "uniprot_id": "HRR25_YEAST", "id": "P29295-1", "name": "Casein kinase I homolog HRR25", "aln": "-----------MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGDLNANSNAASASNSTDNKSETFNKIKLLAMKKFPTHFHYYKNEDKHNPSPEEIKQQTILNNNAASSLPEELLNALDKGMENLRQQQPQQQVQSSQPQPQPQQLQQQPNGQRPNYYPEPLLQQQQRDSQEQQQQVPMATTRATQYPPQINSNNFNTNQASVPPQMRSNPQQPPQDKPAGQSIWL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** *::: ************ . .: .*****:*:** ::***** **:::*: *.****:* ** .*: ::*.:*:************:* *:*::***:**. **: *::*:* : **************:**: ..:.:*****:**:** .*::** ***:*.*********:*:***********:******::** : *****:** **:***::* ***:...:*.**.* * ** *: **:.*:*:* ***::* :**: * .*::: *: :***** :*: * ..: :* : . ", "identical_positions": 174, "similar_positions": 91, "identity": "34.46%" }, { "cls_id": "homologset.agr.MGI:1934960", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L2B0-1", "uniprot_id": "A0ABK0L2B0_RAT", "id": "A0ABK0L2B0-1", "name": "", "aln": "MS-REATEAPAMPEAGR--NKPKARLLLGTDRKRSRLNRTRQDLWDDTSWSNHRLSRVTSAPRRTRARGTAHGRSEASPENAARERTRVKTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRTLGH-ELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGCSGPESTTADSTTTIATDHRSRDAQLGSQVSVATDSLLASP-VSPALGNE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLR5-1", "uniprot_id": "TCF23_MOUSE", "id": "Q9JLR5-1", "name": "Transcription factor 23", "aln": "MS-QEATEAPAMPGEGHGHNKAKARWLLGTDRKRSRINRTRQDLWEDTSWSNHRLSRATSAPRGTRARGTAHGRSEASPENAARERTRVKTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRTLGH-ELPGPAWPPFVRGLRYLHPLKKWPMRSRLYAGGLGCS-----DLDSTTAITTGQRCKDAELGSQDSVAAESLLTS----PAFGNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU1-1", "uniprot_id": "TCF23_HUMAN", "id": "Q7RTU1-1", "name": "Transcription factor 23", "aln": "MSQRKARGPPAMPGVGHSQTQAKARLLPGADRKRSRLSRTRQDPWEERSWSNQRWSRATPGPRGTRAGGLALGRSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLGH-ELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGYS-----DLDSTTASTPSQRTRDAEVGSQVPGEADALLSTTPLSPALGDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PV37-1", "uniprot_id": "A0A8M1PV37_DANRE", "id": "A0A8M1PV37-1", "name": "", "aln": "MAERALDEDMAWQ--------------RGEDGGKSLRTQTWNQTCVKLATQREAKKWVKSGPTAS----SRACKSQTSPENAARERSRVRNLRQAFHSLQAALPSVPPDTKLSKLDVLVLATNYIAHLTETLDQGGMLGDQS--VLQRVEYLHPVKKWPMRSLLYCG------------------NIGERLTGAQVSQETASKAESRLTN----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : * * * :* .:* :: . : ... . ....* : :*::*********:**:.***** :******:****************:.******.**.: : * .:: :.****:******* **.* ..* .*::..: . ::: *:. ", "identical_positions": 72, "similar_positions": 53, "identity": "32.73%" }, { "cls_id": "homologset.agr.MGI:1935037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIL6-1", "uniprot_id": "GPC5D_MOUSE", "id": "Q9JIL6-1", "name": "G protein-coupled receptor family C group 5 member D", "aln": "MYEDCVKSTEDYYLFCDNEGPWAIVLESLAVIGIVVTILLLLAFLFLMRKVQDCSQWNVLPTQFLFLLAVLGLFGLTFAFIIQLNHQTAPVRYFLFGVLFAICFSCLLAHASNLVKLVRGRVSFCWTTILFIAIGVSLLQTIIAIEYVTLIMTRGLMFEHMTPYQLNVDFVCLLIYVLFLMALTFFVSKATFCGPCENWKQHGRLIFATVLVSIIIWVVWISMLLRGNPQLQRQPHWDDAVICIGLVTNAWVFLLIYIIPELSILYRSCRQECPTQGNVCQVPVYQRSFRMDTQEPTRARDSDGAQEDVALTAYGTPIQLQSADPSREYLIPSATLSPQQDAGL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7N4-1", "uniprot_id": "D4A7N4_RAT", "id": "D4A7N4-1", "name": "", "aln": "MYEDCVKSTEDYYLFCDNEGPWAIVLESLAVIGIVVTILLLLAFLFLMRRVQDCSQWNVLPTQFLFLLAVLGLFALTFAFIIQLNQQTAPVRYFLFGVLFAICFSCLLAHASNLVKLVRGRVSFCWTTILFIAIGVSLLQTIIAIEYVTLIMTRGLMFEHMTPYQLNVDFVCLLIYVLFLMALTFFVSKATFCGPCENWKQHGRLIFATVLVSIIIWVVWISMLMRGNPQLQRQPQWDDAVICIGLVTNAWVFLLLYIIPEMSILYRSCRQECPPQGNICQVPVYQRSFRMENQEPTRARDSDGAQEDVALTAHGTPIQLQTVDPSQEYLIP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZD1-1", "uniprot_id": "GPC5D_HUMAN", "id": "Q9NZD1-1", "name": "G protein-coupled receptor family C group 5 member D", "aln": "MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCSQWNVLPTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLVKLVRGCVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRGMMFVNMTPCQLNVDFVVLLVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFITVLFSIIIWVVWISMLLRGNPQFQRQPQWDDPVVCIALVTNAWVFLLLYIVPELCILYRSCRQECPLQGNACPVTAYQHSFQVENQELSRARDSDGAEEDVALTSYGTPIQPQTVDPTQECFIPQAKLSPQQDAGGV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**::** **:*:** ****.*:*****::*****************::************:****:*****.*:*****:**:***************:****************** ***.***** **** **** *** **********:** :*** ******* **:******************************** ***.************:*****:****:***.*:**.**********:**:**:.*********** *** * *..**:**:::.** :********:******::***** *:.**::* :** ", "identical_positions": 266, "similar_positions": 49, "identity": "77.1%" }, { "cls_id": "homologset.agr.MGI:1935121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P1D5-1", "uniprot_id": "SE6L1_MOUSE", "id": "Q6P1D5-1", "name": "Seizure 6-like protein", "aln": "MPVARPQAAGPDRISLFLVAFLLGSPAAAQAEDGGPEGEMHPSTAYLLPSASLES------SLEEGVTSAAPGLLPSQEALEAMEES------------LPPALPDEASVQHTPALRKGLPSLKQLNSARRQLRPLAT-PTTLQRLGSP---------ASATTKLREPEDPE---------------------QPTAPAPLQIAPFT---ALATTLPHSPQP--------AQAP-DDSSPGSPLDKGDNELTGSASEESQETTTSTIVTTTIITTEQAPALCGVSFSDPEGYIDSSDFPPQPYSSFLECTYNVTVYTGYGVELQVKSVNLSEGELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSCPFPRRPDAGEVTVMDLHSGGVAHFHCHLGYELQGAKTLTCINASKPHWSSQEPVCSAPCGGAVHNATIGRVLSPSFPGTANGSQLCVWTIEAPEGQKLHLHLERLLLHEKDRMIVYSGRTNTSALLYDSLRTESVPFEGLLSEGSSIRIEFTSDQGQAASAFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAVIECVNVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVVPHVLGQYFGHSSPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVEHSTRLISDPVLLVGTTIQYTCSPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWSGPLPICKVNQDSFEHALE-AEAAAESSLEGGNMALAIFIPVLLISLLLGGAYIYVTRCRQYSSLRLPLMYSHPYSQITVETEFDNPIYETGETREYEVSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AD89-1", "uniprot_id": "D4AD89_RAT", "id": "D4AD89-1", "name": "Seizure 6-like protein", "aln": "MTVAPPQAAGPDRISLLLVALLLGSPVAARAEDGGPEGDMHPSTAYLLPSALLEG------SLEEGVTSAAPGPLPSREALEALEGS------------LPPLFPDEARVQHTPSLRKALPSLKQLNSARRQLRPLAT-PTTLQRLGSP---------SSATTKPREPGDPE---------------------QPTAPAPLQIAPFT---ALATTLPHSPQP--------AQAP-DDSSLSSPLDKGDNELTGSASEESQETTTSTIVTTTIITTEQAPALCGVSFSDPEGYIDSSDFPPQPSSSFLECTYNVTVYTGYGVELQVKSVNLSEGELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDNLGTFQLHYQAFMLSCNFPRRPDAGDVTVMDLHSGGVAHFHCHLGYELQGAKTLTCINASKPHWSSQEPVCSAPCGGAVHNATIGRVLSPSYPGNTNGSQLCVWTIEAPEGQKLHLHLERLLLHEKDRMVVYSGRTNTSALLYDSLRTESVPFEGLLSEGSNIRIEFTSDQGQAASAFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAVIECVNVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVVPHVLGQYFGNSSPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVEHSTRLISDPVLLVGTTIQYTCSPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWSGPLPICKVNQDSFEHALEVAEAAAESSLEGGNMALAIFIPVLLISLLLGGAYIYVTRCRQYSSLRLPLMYSHPYSQITVETEFDNPIYETGETREYEVSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYH1-1", "uniprot_id": "SE6L1_HUMAN", "id": "Q9BYH1-1", "name": "Seizure 6-like protein", "aln": "MPAARPPAAGLRGISLFL-ALLLGSPAAALERDALPEGDASPLGPYLLPSGAPERGSPGKEHPEERVVTAPPSSSQSAEVLGELVLDGTAPSAHHDIPALSPLLPEEARPKHALPPKKKLPSLKQVNSARKQLRPKATSAATVQRAGSQPASQGLDLLSSSTEKPGPPGDPDPIVASEEASEVPLWLDRKESAVPTTPAPLQISPFTSQPYVAHTLPQRPEPGEPGPDMAQEAPQEDTSPMALMDKGENELTGSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGNMALAIFIPVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYETGETREYEVSI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..* * *** ***:* *:*****.** .*. ***: * .*****. * ** *.:*.*. * *.* : . *.* :*:** :*: . :* ******:****:**** ** .:*:** ** :*:* * * **: **:******:*** :* ***: *:* :** :*:* : :***:*******************:***:**********.****:*********:* * ..**************************:**********************************************.*************** ******:*:************************** ****************:*********************:* .:****:*:**************:******:**** *:**:**.********:*************..*********.:***:***************************************************:***:**************************************.*****:**********************************:**:****:*:*.**************************************************************************************************************:*********************.****************************************************************************************.****:************* ******:****************:***********:**** **.*************************************", "identical_positions": 818, "similar_positions": 88, "identity": "79.8%" }, { "cls_id": "homologset.agr.MGI:1935127", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PGB8-1", "uniprot_id": "SMCA1_MOUSE", "id": "Q6PGB8-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1", "aln": "--------------MEPDTATEAATVAVSDARATVVVVEDEQPGPSTFKEEGAAAAATEGTTATEKGEKK-EKITSPFQLKLAAKASKSEKEMDPEYEEKMVNMPLKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRV-KKDDKQSLISVGDYRHRRTEQEEDEELLSESRK----TSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVGNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYSRLDGQTPHEEREEAIDAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNKLAKEEMLQMIRHGATHVFACKESELT-------------DEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDL-----EQSLYKFEGEDYREKQKLG---------------------TVEWIEPPKRERK---ANYAVDAYFREALR------VSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPEIP---------NPAIAQ------------REEQKKIDGAEPLTPQETEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVE-GKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYG--TSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKEN---MEIEERERAEKKKRAT---------KTPMVKFSAFS---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YCJ3-1", "uniprot_id": "A0A8I5YCJ3_RAT", "id": "A0A8I5YCJ3-1", "name": "", "aln": "--------------MEPDTATEAATVAASDARATIVVLEDEQPGPSTFKEEGAAAAATEATTATEKGEKK-EKITSPFQLKLAAKTSKSEKEMDPEYEEKMVNIPLKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRV-KKDDKQSLISVGDYRHRRTEQEEDEELLSESRK----TSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNFPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVSNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNKLAKEEMLQMIRHGATHVFACKESELT-------------DEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDL-----EQSLYKFEGEDYREKQKLG---------------------TVEWIEPPKRERK---ANYAVDAYFREALR------VSEPKVPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPELP---------NPAIAQ------------REEQKKIDGAEPLTPQESEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNVAREVE-GKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYG--TSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKEN---MEIEERERAEKKKRAT---------KTPMIEEESHHKR----------TSLLFEEHVVRNSLVTRLSI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28370-2", "uniprot_id": "SMCA1_HUMAN", "id": "P28370-2", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1", "aln": "--------------MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKNVSSFQLKLAAKAPKSEKEMDPEYEEKMK-----ADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLGRPRI-KKDEKQSLISAGDYRHRRTEQEEDEELLSESRK----TSNVCIRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNKLAKEEMLQMIRHGATHVFASKESELT-------------DEDITTILERGEKKTAEMNERLQKMGESSLRNFRMDI-----EQSLYKFEGEDYREKQKLG---------------------MVEWIEPPKRERK---ANYAVDAYFREALR------VSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPDIP---------NPALAQ------------REEQKKIDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVE-GKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYG--TSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKEN---MEIEERERAEKKKRAT---------KTPMVKFSAFS---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WUY4-1", "uniprot_id": "A5WUY4_DANRE", "id": "A5WUY4-1", "name": "", "aln": "-------------------------------------MSDEE-LPSTSREAHAEAEEED----------------PPFLLGPPPKAVVKESLADPEYEEKRK-----TDRANRFEFLLKQTELFAHFIQPASQKSPTSPLKVKMGRPRI-KQDEKQNLLSVGDNRHRRTEQEEDEELLSESRK----ADNVLVRFEESPSYIKNGTLRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPTLKAVCLIGNKDERAAFIRDVMMPGEWDVCVTSYEMVIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIAREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSASDFDSWFDTN-CLGDQ-KLVERLHAVLRPFLLRRIKAEVEKSLPPKKEVKIYLGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDTHLVINSGKMVALDKLLPKVQEQGSRVLIFSQMTRVLDILEDYCMWRGFEYCRLDGNTPHEAREQAIDAFNAPNSSKFIFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQRKPVKVFRLITDNTVEERIVERAEMKLRLDSIVIQQGR--LIDQQ-NKLGKDEMLQMIRHGATHVFASKDSELT-------------DEDIDTILERGAKKTAEMNERMQNLGESSLRNFTVDTG--ATETSLYNFEGEDYREKQKVGVFIFGHLIFVHIAVLKSINLSLIEWIEPPKRERK---ANYAVDAYFREALR------VSEPRAPKAPRPPKQPNIQDFQFFPPRLFELLEMEILYYRKTIGYKVP--------RSPDIP---------NSAQVQ------------KEEQRKIDEAEPLSPEETEEKEKLLTQGFTNWNKRDFNQFIKANEKYGRDDIDNIAREVE-GKTPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDVKIARYKAPFHQLRIQYG--TNKGKNYTEEEDRFLICMLHKMGFDKEYVYEELRQCVRNAPQFRFDWFIKSRTAMELQRRCNTLISLIEKEN---MEIEEKERAEKKRRTP---------KGQSAQKRKAEVS----------SEKKEKKART-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24368-1", "uniprot_id": "ISWI_DROME", "id": "Q24368-1", "name": "Chromatin-remodeling complex ATPase chain Iswi", "aln": "----------------------------------------------MSKTDTAAVEATE----------------ENSNETTSDAATSSSGEKEAEFDNKIE-----ADRSRRFDFLLKQTEIFTHFMTNSA-KSPTKPK----GRPKK-IKD-KDKEKDVADHRHRKTEQEEDEELLAEDS-----ATKEIFRFDASPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWFNTNTCLGDD-ALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAG--KVEKMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGR--LVDNRSNQLNKDEMLNIIRFGANQVFSSKETDIT-------------DEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLN--------------------ALGNWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVP--------KNTELGS--------DATKVQ------------REEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKANEKYGRDDIDNIAKDVE-GKTPEEVIEYNAVFWERCTELQDIERIMGQIERGEGKIQRRLSIKKALDQKMSRYRAPFHQLRLQYG--NNKGKNYTEIEDRFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTLITLIEREN---IELEEKERAEKKKKAP---------KGSVSAGSGSASSNTPAPAPQPKASQKRKSEVVATSSNSKKKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08773-1", "uniprot_id": "ISW2_YEAST", "id": "Q08773-1", "name": "ISWI chromatin-remodeling complex ATPase ISW2", "aln": "--------------MTTQQEEQRSDTKNSKSESPSEVLVDTLDSKSNGSSDDDNIGQSEELSDKEIYTVE-----DRPPEYWAQRKKKFVLDVDPKYAKQKD----KSDTYKRFKYLLGVTDLFRHFIGIKAKHDKNIQKLLKQLDSDANKLSKSHSTVSSSSRHHRKTEKEEDAELMADEEEEIVDTYQEDIFVSESPSFVKSGKLRDYQVQGLNWLISLHENKLSGILADEMGLGKTLQTISFLGYLRYVKQIEGPFLIIVPKSTLDNWRREFLKWTPNVNVLVLHGDKDTRADIVRNIILEARFDVLITSYEMVIREKNALKRLAWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWFEQNNSEQDQEIVIQQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQWYKSLLEKDIDAVNGAVGKREGKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLIFNSGKMIILDKLLKRLKEKGSRVLIFSQMSRLLDILEDYCYFRDFEYCRIDGSTSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGT--GKKTASLGNSKDDLLDMIQFGAKNMFEKKASKVTV------------DADIDDILKKGEQKTQELNAKYQSLGLDDLQKFNGIE-----NQSAYEWNGKSFQKKSNDK---------------------VVEWINPSRRERRREQTTYSVDDYYKEIIGGGSKSASKQTPQPKAPRAPKVIHGQDFQFFPKELDALQEKEQLYFKKKVNYKVTSYDITGDIRNEGSDAEEEEGEYKNAANTEGHKGHEELKRRIEEEQEKINSAPDFTQEDELRKQELISKAFTNWNKRDFMAFINACAKYGRDDMENIKKSID-SKTPEEVEVYAKIFWERLKEINGWEKYLHNVELGEKKNEKLKFQETLLRQKIEQCKHPLHELIIQYPP-NNARRTYNTLEDKFLLLAVNKYGLRADKLYEKLKQEIMMSDLFTFDWFIKTRTVHELSKRVHTLLTLIVREY---EQPDANKKKRSRTSATRE-------DTPLSQNESTRASTVPNLPTTMVTNQKDTNDHVDKRTKIDQEA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38144-1", "uniprot_id": "ISW1_YEAST", "id": "P38144-1", "name": "ISWI chromatin-remodeling complex ATPase ISW1", "aln": "MAYMLAIANFHFFKFYTRMRKKHENNSCNEKDKDENLFKIILAIFLQEKKKYDCISSGSIMTASEEYLEN----LKPFQVGLPPHDPESNKKRYLLKDANGKK-FDLEGTTKRFEHLLSLSGLFKHFIESKAAKDPKFRQVLDVLEENK---ANGKGKGKHQDVRRRKTEHEEDAELLKEEDSD--DDESIEFQFRESPAYVN-GQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDLDAVNGSNGSKESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTSLKKKENKADSKDALLSMIQHGAADVFKSGTSTGSAGTPEPGSGEKGDDIDLDELLLKSENKTKSLNAKYETLGLDDLQKFNQDS--------AYEWNGQDFKKKIQRD-------------------IISPLLLNPTKRERK---ENYSIDNYYKDVLN------TGRSSTPSHPRMPKPHVFHSHQLQPPQLKVLYEKERMWTAKKTGYVPTMDDVK--AAYGDISD--------EEEKKQ----------KLELLKLSVNNSQPLTEEEEKMKADWESEGFTNWNKLEFRKFITVSGKYGRNSIQAIARELAPGKTLEEVRAYAKAFWSNIERIEDYEKYLKIIENEEEKIKRVKMQQEALRRKLSEYKNPFFDLKLKHPPSSNNKRTYSEEEDRFILLMLFKYGLDRDDVYELVRDEIRDCPLFELDFYFRSRTPVELARRGNTLLQCLEKEFNAGIVLDDATKDRMKKEDENGKRIREEFADQTANEKENVDGVESKKAKIEDTSNVGTEQLVAEKIPENETTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . .**..** : :* **: : :. . . . . ::*:**:*** **: :. . . . **:::: * :* **::*:**::**::* : ****************::****:: .: **.:::.*****.** .*: :* * :... : *::: * :::. :: :** ::***: *:**. :*:: *.*::**********:* **:: * * : ****:*************:********:*..:. **.**. : *: :: :**:**.******:*::**. * ** * ::::*::.** .**. :* **:* :*.: : * ** **:****** ******:*********** *:: *:.*: ***** :::*:**********:*:******** :*.::*.*:**.*.** * . *: :* :* **:*:*:**********.:**.*:::******* *************:* *:*:*::*:.::**:::*** *****.:*** . . *: :*.:*:.** .:* : : * *: :* :. ** . : :.:* ..*:.* *:::*:.:::* : ::*.:***: .*::* *::: : .. *. ** ** :..*: * .* * : * : *. .* . : : . : .:: : :: :: * . ::.** *.* :* **.. ****:.:: : :.: .*: *** * **.. .::. *: : :* * : :: : * *: . : *:.:* ::: .. :.*. **:*:: : * *: : :** :: : . * :*:::::** *: :* :**: : :* : : . : ", "identical_positions": 347, "similar_positions": 311, "identity": "29.01%" }, { "cls_id": "homologset.agr.MGI:1935129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQQ5-1", "uniprot_id": "A0A8I5ZQQ5_RAT", "id": "A0A8I5ZQQ5-1", "name": "", "aln": "------------------MSSTAEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPSATGAGPADTEMEEVFDDGSPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTP-TSPLKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFE----DSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAGPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEG-KTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYG--TNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGPKPS---------------------TQKRKMDGAPDGRGRKKKLKL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZW3-1", "uniprot_id": "SMCA5_MOUSE", "id": "Q91ZW3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "------------------MSSAVEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTP-TSPLKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFE----DSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEG-KTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYG--TNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGPKPS---------------------TQKRKMDGAPDGRGRKKKLKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60264-1", "uniprot_id": "SMCA5_HUMAN", "id": "O60264-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "------------------MSSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTP-TSPLKMKPGRPRIKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFE----DSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILFYRKTIGYKVP--------RNPELP---------NAAQAQ------------KEEQLKIDEAESLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEG-KTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYG--TNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGPKPS---------------------TQKRKMDGAPDGRGRKKKLKL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A552-1", "uniprot_id": "B8A552_DANRE", "id": "B8A552-1", "name": "", "aln": "-------------------MSQTESSMEQQREEEPSQLDPAGP-AEDDTSENGHDEASDTAMDSEAQSSSPPSAKGKDLLGG---------------YEEKVQTDRTNRFEYLLKQTEVFAHFIQPAAQKTP-TSPLKMKPGRPRIKKDEKQNLLSAGDNRHRRTEQEEDEELLSENSKATSVCTRFD----DSPSYVKTGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLYNWMNEFKRWVPSLKAVCLIGDREERTAFIRDTLLPGEWDVCVTSYEMLIIERAVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSSEDFDAWFDTNNCLGDT-KLVERLHTVLRPFLLRRIKADVEKSLLPKKEIKIYVGLSKMQREWYTKILMKDIDILNSAG--KMDKMRLLNVLMQLRKCCNHPYLFDGAEPGPPYTTDLHLVVNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYGYCRLDGQTPHEERQISINAFNEPNSSKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQVDLQAMDRAHRIGQKKQVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDPSMNKLGKDEMLSIIRHGATHVFASKESEIT-------------DEDIDGILERGERKTMEMKEKMANLGEGSLRNFTMDT-----ENSVYNFEGEDYREK-KKVVT--NWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPDLP---------NSAEMQ------------KEEQAKIDEAEPLNEEELEEKENLLSQGFTIWTKRDFNQFIKANEKWGRDDIENIAREVEG-KTPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDSKIGRYKAPFHQLRISYG--TNKGKNYTEEEDRFLICMLHKLGFDKESVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEREKAEKKKRGPRTSS--------------------AQKRKQDGTPDGRGRKKKLKL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24368-1", "uniprot_id": "ISWI_DROME", "id": "Q24368-1", "name": "Chromatin-remodeling complex ATPase chain Iswi", "aln": "-------------------MSKTDTAAVEATEENSNE----------------------TTSDAATSSSGEKEAE----------------------FDNKIEADRSRRFDFLLKQTEIFTHFMT-NSAKSP-TKPK----GRPKKIKD-KDKEKDVADHRHRKTEQEEDEELLAEDS-ATKEIFRFD----ASPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWFNTNTCLGDD-ALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAG--KVEKMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGR--LVDNRSNQLNKDEMLNIIRFGANQVFSSKETDIT-------------DEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLNALG-NWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVP--------KNTELGS--------DATKVQ------------REEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKANEKYGRDDIDNIAKDVEG-KTPEEVIEYNAVFWERCTELQDIERIMGQIERGEGKIQRRLSIKKALDQKMSRYRAPFHQLRLQYG--NNKGKNYTEIEDRFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTLITLIEREN---IELEEKERAEKKKKAPKGSVSAGSGSASSNTPAPAPQPKASQKRKSEVVATSSNSKKKKK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08773-1", "uniprot_id": "ISW2_YEAST", "id": "Q08773-1", "name": "ISWI chromatin-remodeling complex ATPase ISW2", "aln": "-------------------MTTQQEEQRSDTKNSKSESPSEVLVDTLDSKSNGSSDDDNIGQSEELSDKEIYTVEDRPPEYWAQRKKKFVLDVDPKYAKQKDKSDTYKRFKYLLGVTDLFRHFIGIKAKHDKNIQKLLKQLDSDANKLSKSHSTVSSSSRHHRKTEKEEDAELMADEEEEIVDTYQEDIFVSESPSFVKSGKLRDYQVQGLNWLISLHENKLSGILADEMGLGKTLQTISFLGYLRYVKQIEGPFLIIVPKSTLDNWRREFLKWTPNVNVLVLHGDKDTRADIVRNIILEARFDVLITSYEMVIREKNALKRLAWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWFEQNNSEQDQEIVIQQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQWYKSLLEKDIDAVNGAVGKREGKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLIFNSGKMIILDKLLKRLKEKGSRVLIFSQMSRLLDILEDYCYFRDFEYCRIDGSTSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGT--GKKTASLGNSKDDLLDMIQFGAKNMFEKKASKVTV------------DADIDDILKKGEQKTQELNAKYQSLGLDDLQKFNGIE-----NQSAYEWNGKSFQKKSNDKVV--EWINPSRRERRREQTTYSVDDYYKEIIGGGSKSASKQTPQPKAPRAPKVIHGQDFQFFPKELDALQEKEQLYFKKKVNYKVTSYDITGDIRNEGSDAEEEEGEYKNAANTEGHKGHEELKRRIEEEQEKINSAPDFTQEDELRKQELISKAFTNWNKRDFMAFINACAKYGRDDMENIKKSIDS-KTPEEVEVYAKIFWERLKEINGWEKYLHNVELGEKKNEKLKFQETLLRQKIEQCKHPLHELIIQYPP-NNARRTYNTLEDKFLLLAVNKYGLRADKLYEKLKQEIMMSDLFTFDWFIKTRTVHELSKRVHTLLTLIVREY---EQPDANKKKRSRTSATREDTPLSQNESTRASTVPN--LPTTMVTNQKDTNDHVDKRTKIDQEA------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38144-1", "uniprot_id": "ISW1_YEAST", "id": "P38144-1", "name": "ISWI chromatin-remodeling complex ATPase ISW1", "aln": "MAYMLAIANFHFFKFYTRMRKKHENNSCNEKDKDENLFKIILAIFLQEKKKYDCISSGSIMTASEEYLENLKPFQVGLPPHDPESNKKRYLLKDANGKKFDLEG-TTKRFEHLLSLSGLFKHFIESKAAKDP---KFRQVLDVLEENKANGKGKGKHQDVRRRKTEHEEDAELLKEEDSDDDESIEFQFR--ESPAYVN-GQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDLDAVNGSNGSKESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTSLKKKENKADSKDALLSMIQHGAADVFKSGTSTGSAGTPEPGSGEKGDDIDLDELLLKSENKTKSLNAKYETLGLDDLQKFNQDS--------AYEWNGQDFKKKIQRDIISPLLLNPTKRERK---ENYSIDNYYKDVLN------TGRSSTPSHPRMPKPHVFHSHQLQPPQLKVLYEKERMWTAKKTGYVPT-------MDDVKAAYG-------DISDEE------EKKQKLELLKLSVNNSQPLTEEEEKMKADWESEGFTNWNKLEFRKFITVSGKYGRNSIQAIARELAPGKTLEEVRAYAKAFWSNIERIEDYEKYLKIIENEEEKIKRVKMQQEALRRKLSEYKNPFFDLKLKHPPSSNNKRTYSEEEDRFILLMLFKYGLDRDDVYELVRDEIRDCPLFELDFYFRSRTPVELARRGNTLLQCLEKEFNAGIVLDDATKDRMKKEDENGKRIREEFADQTANEKENVDGVESKKAKIEDTSNVGTEQLVAEKIPENETTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. . : . . : .**..** : :* **: : : . . . . ::*:**:*** **: :.. . : **:::: *::* **::*:**::**::* : *****************:***::: .: **.:::.***** ** *: :* * :. . * **:: * :::. :: :** ::***: * *: :*:: *.*::**********:* **:::* * : ****:*************:********:*..:: ** **. :. * :: :** **.******:*::**. * ** * :::**::.** .**. :* **:* :*.: : * ** *::****** ******:*********** **: *:.*: :***** :*:*:**********:*:******** :*:: ***:**.*.*::* *: :* :* **:*:*:**********.:**.*:::******* *************.* *:*:*::*:.::**:::*** *****.:*** . . .** :*.:*:.** .:* . : : * *:* :* :. ** . : .:* ..*:.*. .*:::*:.:::* : ::*.:***: .*::* *::: : .. *. ** ** :..*: * .* * ::* : *. .* . . : :. : . : .::.: :.:*: * . ::.** *.* :* **.. *:**:.:: * :.: ** *** * **.. .::. *: : :* * : :: : * *: . : *:.:* :.: .* :.*. **:*:: : * *: :.:*: :: * . * :*:::::** ** :* :**: : :* : : . :. . . : : . . : . ", "identical_positions": 356, "similar_positions": 320, "identity": "30.35%" }, { "cls_id": "homologset.agr.MGI:1935145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K809-1", "uniprot_id": "A0A0G2K809_RAT", "id": "A0A0G2K809-1", "name": "", "aln": "-----------------------------------------------------MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTS------------RHSSGG----------------------------GGGAGGGGSGGSGSGTS--GGGGGTGGGGSSNSFLSGRRSRSASPSTQQEKHPTHHEKGQKKSRKDKER-----------------------LKQKHKKRPESPPSILAPPVVP----------------TADKVS--ATTSSHHEASTQETSESSRDSKGRKSSSHSLSHK---GKKLGSGKGVSSFTSASSSSSSSSSSSSS------------GGPFQPAGSSLQSSPDFAAFPKLEQPEDDK--------YSKPPAPTPPAPPSPTIPEPPKADLFEQK------------------VVFSGFGPIMRFTTTTSSSSRARAP----SPGDYKSPHVSGSGTSAG----------------------------SHKRMPALSATLGPAEEAPETTLKEKKHKASKRSR-------------------------------------------------HGPGRPKGSRGKEGATGPTA-SLPAAQLAGFTATAASPFSGGSLVSSGLGG-LAPRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHG-------------------GGMLRAVCSTP-----LSSSLLGPTGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFS--------LPASHIFGTPMG----TVNPLLTQAESSHTEPDLEDCSFRCHGTSPQ-ESLSSMSPISSLPALFDQTS-APCGGGQLDSTAPGTTNMEQLLEKQ----------GDGEAG-----------VNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLLPQAGSSDSLSISKSPPGKNCLGLDNTLSTSSEDPHSGCPSRSSSSLSFHSTPPP---LPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPG---------------AAGLGAMPMAEGLLGGLAGSGSLPLNGLLGG---------LNGAAAPNPAGLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQ--------LQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGG--------------------------------------------SQLPMASLLAGSST--------------------------PLLSAG------------TPGLLPTASAPPLLPAGALVAPSLGSNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLPGADASGNGSKGGTADKGASASQEKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AR10-1", "uniprot_id": "B1AR10_MOUSE", "id": "B1AR10-1", "name": "", "aln": "-----------------------------------------------------MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTS------------RHSSGG----------------------------GGGAGGGSSGGGGGGSSSASGGGGGTGGGSGNSFLSGRRSRSASPSTQPEKHPTHHEKGQKKSRKDKER-----------------------LKQKHKKRPESPPSVLAPPAVP----------------TADKVSS-ATSSSHHEASTQETSESSRDSKGRKSSSHSLSHK---DKKLGTGKGVSSFTSASSSSSSSSSSSSSS----------SGGPFQPAGSSLQSSPDFAAFPKLEQPEEDK--------YPKPADPTPPAPPSPTAPEPPKADLFEQK------------------VVFSGFGPIMRFTTTASSSSRARAP----SPGDYKSPHITGAGASAG----------------------------THKRMPALSATLGPAEEAPETTLKEKKHKASKRSR-------------------------------------------------HGPGRPKGSRGKEGASGPTA-SLPAAQLAGFTATAASPFSGGSLVSAGLGG-LASRTFGPSGSLPSLSLESSLLGAGIYTSNKDPISHG-------------------GGMLRAVCSTP-----LSSSLLGPTGTSALPRLSRSPFTSTLASSSASISTTQVFSLAGSTFS--------LPSSHIFGTPMG----TVNPLLTQAESSHTEPDLEDCSFRCHGTSPQ-ESLSSMSPISSLPALFDQTS-APCAGGQLDSTAPGTTNMEQLLEKQ----------GDGEAG-----------VNIVEMLKALHALQKENQRLQEQILSLTAKKERLQVLNVQLSVPFPALPAALPATNGPIPGPYGLLPQAGSSDSLSVSKSPPGKNSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPP---LPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPG---------------ATGLGAMPMAEGLLGGLAGSGSLPLNGLLGG---------LNGAAAPNPAGLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQ--------LQQLQQLLASPQLTPEHQTVVYQMIQQMQQKRELQRLQMAGG--------------------------------------------SQLPMASLLAGSST--------------------------PLLSAG------------TPGLLPTASAPPLLPAGALVAPSLGSNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLPGADASGNGPKGGTADKGASTSQEKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55198-1", "uniprot_id": "AF17_HUMAN", "id": "P55198-1", "name": "Protein AF-17", "aln": "-----------------------------------------------------MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTS------------RHSSGG----------------------------GGGGAGG-------------GGGSMGGGGSG--FISGRRSRSASPSTQQEKHPTHHERGQKKSRKDKER-----------------------LKQKHKKRPESPPSILTPPVVP----------------TADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHK---GKKLSSGKGVSSFTSASSSSSSSSS--SS------------GGPFQPAVSSLQSSPDFSAFPKLEQPEEDK--------YSKPTAPAPSAPPSPSAPEPPKADLFEQK------------------VVFSGFGPIMRFSTTTSSSGRARAP----SPGDYKSPHVTGSGASAG----------------------------THKRMPALSATPVPADETPETGLKEKKHKASKRSR-------------------------------------------------HGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGG-LSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHS-------------------GGMLRAVCSTP-----LSSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFS--------LPSTHIFGTPMG----AVNPLLSQAESSHTEPDLEDCSFRCRGTSPQ-ESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQ----------GDGEAG-----------VNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPP---LPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPG---------------AAGLGAMPMAEGLLGGLAGSGGLPLNGLLGG---------LNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQ--------LQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGG--------------------------------------------SQLPMASLLAGSST--------------------------PLLSAG------------TPGLLPTASAPPLLPAGALVAPSLGNNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLSGAEGSGGGPKGGTADKGASANQEKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KGP1-1", "uniprot_id": "A0A0B4KGP1_DROME", "id": "A0A0B4KGP1-1", "name": "", "aln": "MCERNNNKQVTSSNKIPSSFNAKLELDSSKDDTIHSTSLNKKLVKIKKFKLDDMKEMVGGCCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSRVRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKTIPPYKPIQHDTSSDSCSSPEKEIDSTMNSATTSATIIKITSSSGSAGGSSNVLNASSSAGISAGSSSGSGVSSSAKQRKSNASSKSSSSSSSSSSSSTGGAPNPSSSSVHSGSASNMTGGGSVLPGSSNIGNISNSLNNNLPGGSSSTSSAGNVPGGSGGIISASSGGATQSTSSQSSTAPGTTKSSASSSSSSSNSYKEKHSKSLSKSTSSKDKDGKDSSTNSANNNFTNSSASSTSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSSINTQPSSSTSTATAGSGGTGTHVSSSAASGLNSAPSTTNEHSNHAHTLSTNGTGAGSAAGKLQSVSNLSNSSSGFGSDLRSVSTSSSSTVNDSTGGFGSNSNSERENLSGAGSSASNMPGTIAPGTGGVSSSAATNLSTNKGGSSSSTANSLTSTSTSSGSSSNSSSKKRKADSAKSTSSISTSGSALEDNNSLISRYDIKDVQVALTPLTDFEKEIEKSSKRQRTELSPPTHQTSATAEVNAPLASSTSASIAVTASATAASAPPATGTTTLGSSISGNAGSTSSGNSSGVSATGGAQSAVGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQASTASSSSAPSLYVSVPLSTANVPGINLPTSSTSSSTTSESHSASSRSSGAQSQHQQQLSNALVGPPMGGSAGAFHGGTTSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISASGFPLPSGNLTATTTESGNLKISYEKQTTRVQQLQEQEAPPARRSRSRSGESGSSHHHAHAHHHHHHPTHHNSHHQQNPQQQQQLHQQQQQNASSHMHACTNSSSSTSTSTTSSSLSGGTAPATSSSNSKGPSRSGKKRGAAMNKSESTSVATTATPATVAATPAEKQSRHSSPHYSATPTPPPTSTLPPVVSSPVVMLQSLSSSSIDSPPATAAAGATSNSRNTRNNSSNGNHNGEQTSSSSSSSSSSSSGGGGTSGAANVVNLLDSPVNMSASGNYRSSSNSTGNALPAASSNASQAKPLNKKMLRAQQTQLYQQQQQQQQYAPPARSISPTNLSSASASNSASLTHLQQQQQSHQQHEDLEILQFTNTNTTASSNTPTSKPNNRTLDLSTASASSSSPSAVPATTSPLVVLSNQLPLNSVAASSSTGGLKFTYESQTQMDVPMMPVSAIKDSPPSSPGSEIGSAMHSATTAPGSLTGASTAATAQPGNVRKRGRKAKDATIAAAAAAAAAAAALSNSQQDLKDVRILQN-GASNTPGNPAGSTPTPPATPASSNAVSSASSIITHTAAHMLGNQINPNSSVAQKLSEQLHMEVQDHSIYTPDSMNSQYAGVPFPGKQRNSTAVPSNATPAQNPLQSMFSGGGMNGNMPIPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLNCLHQLQSENLRLEEHVTSLIARRDHLLAVNARLQIPLSTIASNTKAEAHGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****************.*********: *:*********** ******:*********::******** :*****:***.**************:*.** *****:*. :*::*:.******:* *: .:* **** **: .*:* ******* ****** :*********::*:**:*.. :*.:.. ..*..** ..*. *.* . . : . *:..*:. .. .: * :. ... : :. ::: * ...* :. ** ::.. * *. ::: .**:..:*..* ..* ** *:* * * .*. .:... ..**.:*:**:**.* : .. . .* ***.::..: : *. . . .... . :.**.: .. :*. :. : ****. :* :*:*** :. * .: : :::*:*:**. : . :*::* .: .:.:: *::* .::* : * : ..: : .: .:: * . * *. **::*.* :* : :.:.:.* .. : * *..:.: . .. :*:* *...:.. * . *. :: :.*:. :** .*. ::* : . .*.:**:* ***. *.* * :. :.*.*** :.: :.* ** . : .. * . ** . :* .*: . *.:* .: : :. .*:*. : *. * *::* .**:* : :: * : ::*: .* . .*... * . *.. .: .::*.. ..* ... . : *... . : . . ...:. : :* : * . . :**. * .**** ** : .**..: :*..:. ** . . . : . :. .: . :.. ** . **. : .**.. ..:: .. .*. *.. .: * : * ** :* ***:** . :* ::. .. * : * *. **:.:*: **::. .***: *: *.*** * *.* :** *. **:.. .* : . : : :********.*** . . : :*. **. : ... *.*. *:. ..:. ", "identical_positions": 341, "similar_positions": 414, "identity": "19.85%" }, { "cls_id": "homologset.agr.MGI:1935147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3E3-1", "uniprot_id": "D4A3E3_RAT", "id": "D4A3E3-1", "name": "", "aln": "MAAQVAPAAASSLGNPPPPP-SELKKAEQQQREEAGGEAAAAAAE-RGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGG----SSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP-PQAYALSSPRGGTPGSG-AAAAGSKPPPSSSASASSSSSSFAP--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSAR--GYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAS-GGAQQRSHHAP-MSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQ--QGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQ--SPHPQQQQQ-------------PPYSQQPPSQ---TPHAQP--SYQQQPQTQQPQLQSSQP---PYSQQPSQPPHQQSQTPYPSQ-QSTTQQHPQSQP--------------PYSQPQAQAPYQQQQP---QQPASST--------------LSQQAAYPQPQPQQSQQTAYSQQ-----RFPPP-QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGMGSYQQN-SMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPS--AGMAGSMNPLGAGGQMHGQPGIPPYGTLPPGRMTHASMGNRPYG------------PNMANMPPQVGSGMCPPPGGMNRKTQES--AVAMHVAANSIQNRPPGYPNMNQGGIMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERG-EDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQD------AFPDGSEPTFQKRNSMTPNPGYQPSMNTSDMMGRMS-YEPNKDPYGGMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGN-------------VAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQQ--------------------QQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQTTMY-QQQQQQNYKRPMDGTYGPPAKRHEGELYSVPYSTGQGQPQQQQLPAAQSQSASQPQAAQPSP---QQDVYNQYSNAYPATATAATERRPAGGPQNQFPFQFGRDR---------VSAPPGSNAQQNMPPQMMGG---PIQASAEVAQQGTMWQGRNDMTY-NYANRQNTGSAP-QGPAYHGVNRTDEMLHTDQRANHEGPWPSHG-TRQPPYGPS-----------APVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSP------------------------------FLHSGMKMQKAGPPVPASHIAPTPVQPP------------------------------------------MIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRLTKVSS---PAPTEE-EEEEE-----------------------HVDPKLEEEEEE-GVENDEEMAFLGKDKP-----------------PSEKSEEKLVSKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPCVPSPVPPRKHVTTVEGTPG---------------------------TTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGTKST-EANKESSKFPFGISPAQ-------------------SHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNAIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCD----KVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQSPPFEP-TSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BH40-1", "uniprot_id": "ARI1A_MOUSE", "id": "A2BH40-1", "name": "AT-rich interactive domain-containing protein 1A", "aln": "MAAQVAPAAASSLGNPPPPP-SELKKAEQQQREEAGGEAAAAAAE-RGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLPEPPGGGGGGGSSSSDGVGAPPHSAAAALPPPAYGFGQAYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP-PQAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSAR--GYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAVSGGAQQRSHHAP-MSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQ--QGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQ--SPHPQQQ---------------PPYAQQPPSQ---TPHAQP--SYQQQPQTQQPQLQSSQP---PYSQQPSQPPHQQSPTPYPSQ-QSTTQQHPQSQP--------------PYSQPQAQSPYQQQQP---QQPASSS--------------LSQQAAYPQPQPQQSQQTAYSQQ-----RFPPP-QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGVGSYQQN-SMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPN--AGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMAHASMGNRPYG------------PNMANMPPQVGSGMCPPPGGMNRKTQES--AVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERG-EDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQD------AFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMS-YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGS-------------VAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQ------------------------------HDSYGNQFSTQGTPSSSPFPSQQTTMY-QQQQQ-NYKRPMDGTYGPPAKRHEGEMYSVPYSAGQGQPQQQQLPAAQSQPASQPQAAQPSP---QQDVYNQYSNAYPASATAATDRRPAGGPQNQFPFQFGRDR---------VSAPPGSSAQQNMPPQMMGG---PIQASAEVAQQGTMWQGRNDMTY-NYANRQNTGSAT-QGPAYHGVNRTDEMLHTDQRANHEGPWPSHG-TRQPPYGPS-----------APVPPMTRPPPSNYQPPPSMPNHIPQVSSPAPLPRPMENRTSPSKSP------------------------------FLHSGMKMQKAGPPVPASHIAPTPVQPP------------------------------------------MIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFTKVYS---PAHTEE-EEEE------------------------HLDPKLEEEEEE-GVGNDEEMAFLGKDKP-----------------SSENNEEKLVSKFDKLPVKIVQRNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPYVPCPTPPRKHLTTVEGTPG---------------------------TTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGAKSA-EATKESSKFPFGISPAQ-------------------SHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCD----KVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEP-TSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14497-1", "uniprot_id": "ARI1A_HUMAN", "id": "O14497-1", "name": "AT-rich interactive domain-containing protein 1A", "aln": "MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGG---SSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP-APAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSAR--GYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAS-GGAQQRSHHAP-MSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQ--QGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQ--SPHPQQQQ--------------PPYSQQPPSQ---TPHAQP--SYQQQPQSQPPQLQSSQP---PYSQQPSQPPHQQSPAPYPSQ-QSTTQQHPQSQP--------------PYSQPQAQSPYQQQQP---QQPAPST--------------LSQQAAYPQPQSQQSQQTAYSQQ-----RFPPP-QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQN-SMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPS--AGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYG------------PNMANMPPQVGSGMCPPPGGMNRKTQET--AVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERG-EDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQD------AFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS-YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGN-------------VAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQR------------------------------HDSYGNQFSTQGTPSGSPFPSQQTTMY-QQQQQ-NYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSP---QQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDR---------VSAPPGTNAQQNMPPQMMGG---PIQASAEVAQQGTMWQGRNDMTY-NYANRQSTGSAP-QGPAYHGVNRTDEMLHTDQRANHEGSWPSHG-TRQPPYGPS-----------APVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSP------------------------------FLHSGMKMQKAGPPVPASHIAPAPVQPP------------------------------------------MIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSS---PAPMEGGEEEEE-----------------------LLGPKLEEEEEEEVVENDEEIAFSGKDKP-----------------ASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPRKHVTTAEGTPG---------------------------TTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSS-EAIKESSKFPFGISPAQ-------------------SHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCN----KVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEP-TSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDQ2-1", "uniprot_id": "A0A8M9PDQ2_DANRE", "id": "A0A8M9PDQ2-1", "name": "", "aln": "MAAQVASATSLNTSPP-----SELKKPDRDPKEES--------------VPGEKQQENKEPGLESGSPARGELQDRADVGNAGGGG----------ESEMKNGNGNP---SRVNNN--QNDSTGAEG----NNHPGMVHHHAP-GYQPASYSYAQHYGRAP-----------FHQHGGQQSPGMAAAAGPGALSGSMMDPYQPNSHDHSFPNHQYNSYSPFGNRSPYP-GQGYGMSSPRSAPQAQAVGGQSA-KQQQP------AAAASYSN--QRY-----------NMGNPQPTSTPTLNQLLTSPSGAR--SYPNYPPSDYNS---QDG-AKGPADMA--------SSGGQYGGGHPGWQQRSHHPPPMSPGSTG---QPLGRNQTPG-SMDQMGKMRSQPYGSGGPYSQQPHQGTPSGPQQGPAYPGQGYGPPGPQRYPMGMQGR-------MQYGQQMPSYGQQGPGGYMQQGQQSYYGQHGPSPHPGQQQSPYPQPSPGQAGGQGPYSQQPHATQSSGPHGQTGTPYQQPHMSQQPQGQMTGPSPGPSQSPYSQSSAAASAVPQSSQSPYSQQQVPQSQPSQQASSQAPPASQTQPSYPPGQGPQQQQQPSASQQPPQTPTPASQTPAGHAQMPQGQPTSYSQNPPQQ-QQPQQQQQQSPYQRFPPPPQEISQESFSSQSSAPPSGPPLASKSSTED--MQGRPSSLPDLSGSIDDLPTGTEGALSPGVSTSGVSSSQGEQSNPAQSPFSPHTSP-----------PVGSPASASASRSGPLSPTTMPGNQMPPRPSSGQSDGIIHPSMNQPGMGPDRGYMQRNPQMAPYGSPQSSSALSPRQSSGGQVHPGMVPYQQNNSMANYGPQGGQYGPQG-YPRQPGYSGMPNANYQG--PGIGGSMNPMSG------QGGGPMFAGMPSARMPHGQMGARPYGPNMGPNMSPNMGPNMGNMPPQVASGMCPPPG-LNRKPQD--AGAMQHGPTNSIHNRLPGYPNMSPG-PGMMGSGYGPSMNNMPGMMNTQGSPYPMGANMTNNTSGMSPGPDFG--MDGKLNQAQKMNNKVEGTPKTESKSKKSSSSTTTSEKITRLYELGPEPERKMWVDRYLAFIEEKAMGMTNLPAVGRKPLDLFRLYMSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERG-EDPPPDIMSG-DNKKNQPKIQPPSPAGSGSLQGPQTPQSTSSSMAESGDLKPPTPASTPHSQMPPIP--SGRSSVNLQD------PFADS---DFSRRNTMTPNSGYQSGMSTPEMPGRMGPYEPNKDHFSGMRKVG--EQFMPSGQGQNSSLGDQYNRGPPGPMGN-------------MPMGQRHQYPYGTNYER-RPESGMGPDGSIGPGVPQPNMMPSNAESGMYSPNRYPPQQQR-----------------------------------HDSYSSQYPGQSAPPAGSYPNQQPGMFPQQQSNYK--RPGDGSYPPAKRHHDGEMFGGPYNAQQPQPP-----------TQAPPSGPTSA---QQEMYNQYNSSYPGS-----ERRPPG-AQNQFPFPFGRDR---------MQPGTGPNSQGSMPPQMMGS----QMQSAPDGPQGGMWQGRGDMGYSNYPNRQGPPAGPGQGPGYHTMNRSEDMMSSEPRMNHDGQWPG---PRQPPFGPG-----------GAGPPISRPLQSNYQSPQTMQNHIPQVSSPTPMPRPMESRTSPSKSP------------------------------YMPSNIKMQKAGPPVPASHIVPPSVQPP------------------------------------------MMRRDLSFPPGSIEATPPVLKSRRRLTMKEIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSISNFNLMQLPGFLELIVEYFRRCLIEIFGILREYEVGDPGQRALLDPNVLKEENTVEDEAFMEGMEEDGETEEEEEGEEVQRSKHQEQHAAQVPLQIKQE-EKPMTLEESVKKEDSQGIEGE--SSAETKASEPPCLELAVTQEKPKQASKFDKLPLKIVRKKDPFVVDCSNKLGRLQEFDSGLLHWSIGGGDTTEHIQTHFESKIELLCQRTCLPAQGSDRKKGAQKESQAP------SLPLSSEEHRKEVDRQPSPE-SSTEKVPDEISDPRDNRPADCLDAASEGTSHIEKDQEKQELELTTPESIRPAAPSPLL-------------------QGR-RSVLEDEPHSKDEAPLVTLSEWQDSLARRCICVSNIVRSLSFVPGNDTEMSKHPGLLLLLGRLLLLHHRHPERKQAPLTYEKEEEVDESLGSK----KDEWWWDCLELLRENCLVTLSNISGQLDFSVYTESICLPLLDGLLHWAVCPSAEAQDPFPSLGLNGALSPQRLVLETLCKLSVQDNNVDLILATAPFSRLEKLFGNLVRLVGERKVPVCREMAVVLLANLAQGDSMAARAIAVQKASVGNLLGFLEDSLAATQFQQSQGSLLHMQGSHFEP-TSVDMMRRAARALLALAKVEENHSEFTLYESRLLDLSVSPLMNSMVSHVICDVLFLIGQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PSC1-1", "uniprot_id": "A0A8M9PSC1_DANRE", "id": "A0A8M9PSC1-1", "name": "", "aln": "MAAQVA---TLNTSPP-----AELKKPEREPQDES--------------VIGEKQQESKEPRADGGSPGQKELQDGADVGNAAGGGGAG------GDPDMKNGNGNP---SRVNNNNSQNDSGGPEG----NSHPGMAPHHPG-AFPPPPYSYNQHYNRAP-----------FHQHGGQQSPGMAGPA--------VMDPYPPNSHEHGYPNH-FNNYSPFPNRTPYHQGQGYGMNSPRNS-QPPAAGGQPG-KQPPTGGTTPLATAASYNN--QRY-----------NMGNPQPTSTPTLNQLLTSPSSTR--SYQNYPASEYGG---QEGAAKGPGDMG--------SSS-QYGGGHPAWQQRSHHPPPMSPGNTG---QAN-RTQPPG-PMDQVGKIRGQHYGAGNPYSQQ--QGPPPSSQQGPPYPGQGYGPPGPQRYPMGMQGRTSGNLSGIQYGQQMG-YGQHGPGGYGQN-QAGYYGQQGPSPHGGPQQSSYPQQPSTGPGSQPPYSQQPSGT----PHGQSGTSYGQPQGPHVPN-QGQPPYSQTPQSQSGQSPFPQSQGPTQSQGPSQGQQGSQSQP----GYTHPPSGSGQPAQQQGP-SQQQQGPPQSQTPSSAPPQPSQQTSG-----QGQPSPYSQTPPLQTQQQQQQQQQSPFQRFPPPPQELSQDSFSSQSSAPSSNQPIVSSKSGQDDTMQGRPSSLPDLSGSIDDLPTGTEGALSPGVSTSGVSSSQGEQSNPAQSPFSPHTSPHLSGIRGPSPSPVGSPASGPASRTGPLSPGTMPGNQMPPRPSSVQSDGMLHSSMGQ-----DRVYMR-NPQMP-YGSPQSGSTLSPRQTSGSQMHAGMGSYPQNNSMGNYGPQSGQYGPQG-YPRPPGYGGMPNANYPGG-PGMGGSMNPMAG------QGGGGPYGGMPPGRMGPGQMGTRPYG--------PGMGPNMGGMPPQVASGMCPPPG-MNRKPQDPAAAGMHHGPSNSIH-RPPGYPNMNQG-MMGAGSPYAPPMNSMQGMMNQAG-QYPMPGNMSNNSAGMAPSPEFG--MD-KLNQSQKLNNKVDGTPKTESK-KKSSSSTTTNEKITRLYELGPEPERKLWVDRYLAFAEEKAMGMSNLPAVGRKPLDLFRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERG-EDPPPDFFNN-DPKKNQAKVQPPSPAGSGSLQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQMPPMP--GARSSVNLQD------PFADGGDPAFSRRNSVTPNSGYQPGMGGPDMMGRMGPFEPNKDPFGGMRKAG--EQFMNPGQGPNSGMGEQYNRASQGPMGN-------------MQMGQRQQYPYGPGYDR-RPDSSMGPDGNMGP---QPNMMPSGADAGMYSPNR-PPQQQR-----------------------------------HDSYSNQYAGQGAPPSGPYPNQQSGMYPQQQPNYTQKRPVDGVYGPPAKRHEGDMY--PFSGQQQGP-------------QAP--GAPQS---QSDMYNQYN-TYPGS-----ERRPPG-PQSQFPFGFGRDR---------GPNVGGPNSQPSMPPQMMGSSMSGTMPSVPDGPQGPMWPGRNEMNYPNYHNRQGPPGVPSQSQVYHGMNRSEDMMPSDQRMNQEGPWPGHVNQRQPPYGPV-----------ASGPPMSRPLQPNYQSS---QNHIPQVSSPAPMPRPMENRTSPNKSP------------------------------YMHPGMKIQKAGPPVPASHIAQPPVQPP------------------------------------------MIRRDIAFPPGSIEASQPILKPRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSISNFNLNQLPGFLELVVEYFRRCLIEIFGILKEYEVGDPGQRTLIDPEAIDPEMSDEEGPEAEQMEEDDEDDEED---------LENNTVQTSQVQIKQEKEESMESPKSNDKNELEDREGEDNSCKDHLRSSTPLQDTSASQERPKQASKFDKLPIKIMRKKDPFVIGHTSKLGRRQAFDSGLIHWSVGGGDTTEHIQTHFESKMELLKHRKRVPVNVEPRKKVSQILETVTG----EAEKVQTNEGPQQVQVLASKDQPSLEGKSTTTSSTSTSITATIDDVLSARRGSATEEAVRGNQDSDKEKNTFLFGIDLAQ-------------------QSRNIKILEDEPHSKDETPLCTLSDWQDALARRCICVSNIVRSLSFIPGNDLEMSKHPGLLLLLGRLVLLHHWHPERKQAPVTYEKEEEEDEGVSCE----RDEWWWDCLEVLRENCLVTLANISGQLDLSIYPESICLPLLDGLLHWAVCPSAEAIDPFPTLGLNGTLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYGSLVRMVGDRKVTVCREMAVVLLANLAQGDTVAARAIAVQKGSVGNLLGFLEDSLAATQFQQSQGSLLHLQGSPFEP-TSVDMMRRAARALHALAKVEENHSEFTLYESRLLDISVSPLMNSLVSHVICDVLFLIGQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IN94-1", "uniprot_id": "OSA_DROME", "id": "Q8IN94-1", "name": "Trithorax group protein osa", "aln": "MNEKIKSPQTQQQQQGGAPAPAATPPSAGAAPGAATPPTSGPPTPNNNSNNGSDPSIQQQQQNVAPHPYGAPPPPGSGPGGPPGPDPAAVMHYHHLHQQQQQHPPPPHMQQQQHHGGPAPPPPGGAP----EHAPGVKEEYTHLPPPHPHPAYGRYHADPN---------MDPYRYGQPLPGGKPPQQQQPHPQQQPPQQPGPGGSPNRPPQQRYIPGQP-------PQGPTPTLNSLLQSSNPPPPPQHRYANTYDPQQAAASAAAAAAAQQQQ-------------AGGPPPPGHGPPPPQHQPSPYGGQQGGWAPPPRPYSPQLGPSQQYRTPPPTNTSRGQSPYPPAHGQNSGSYPSSPQQQQQQQQQQQQQAGQQPGGPVPGGPPPGTGQQPPQQNTPPTSQYSPYPQR--YPTPPGLPAGGSNHRTAYS---THQYPEPNRPWPGGSSPSPGSGHPLPPASPHHVPPLQQQPPPPPHVSAGGPPPSSSPGHAP-----------SPSPQPSQASPSPHQELIGQNSNDSSSGGAHSGMGSGPPGTPNPQQVMRPTPSPTGSSGSRSMSPAVAQNHPISRP---------------ASNQSSSGGPMQQPPVGAGGPPPMP----------------PHPGMPGGPPQQQQSQQQQAS-----------NSASSASNSPQQTPPPAPPPNQGMNNMATPPPPPQGAAGGGYPMPPHMHGGYKMGGPGQSPGAQGYPPQQPQQYPPGNYPPRPQYPPGAYATGPPPPPTSQAGAGGANSMPSGAQAGGYPGRGMPNHTGQYPPYQWVPPSPQQTVPGGAPGGAMVGNHVQGKGTPPPPVVGGPPPPQGSGSPRPLN-YLKQHLQHKGGYGGSPTPPQG----PQGYGNGPTGMHPGMPMGPPHHMGPPHGPTNMGPPTSTPPQSQMLQGGQPQGQGASGGPE-----------SGGPEHISQDNGISSSGPTGAAGMHAVTSVVTTGPDGTSMDEVSQQSTLSNASAASGEDPQCTTPKSRKNDPYSQSHLAPPSTSPHPVVMHPGGG-PGEEYDMSSPPNWPRPAGSPQVFNHVPVPQEPFRSTITTTKKSDSLCKLYEMDDNPDRRGWLDKLRAFMEERRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKTWKDIAGLLGIGASSSAAYTLRKHYTKNLLTFECHFDRGDIDPLPIIQQVEAGSKKKTAKAASVPSPGGGHLDAGTTNSTGSSNSQ--DSFPAPPGSAPNAAIDGYPGYPGGSPYPVASGPQPDYATAGQMQRPPSQNNPQTPHPGAAAAVAAGDNISVSNPFEDPIAAGGGPGSGTGPGPGQGPGPGAASGGAGAVGAVGGGPQPHPPPPHSPHTAAQQAAGQHQQQHPQHQHPGLPGPPPPQQQQGQQGQQPPPSVGGGPPPAPQQHGPGQVPPSPQQHVRPAAGAPYPPGGSGYPTPVSRTPGSPYPSQPGAYGQYGSSDQYNATGPPGQPFGQGPGQYPPQNRNMYPPYGPEGEAPPTGANQYGPYGSRPYSQPPPGGPQPPTQTVAGGPPAGGAPGAPPSSAYPTGRPSQQDYYQPPPDQSPQPRRHPDFIKDSQPYPGYNARPQIYGAWQSGTQQYRPQYPSSPAPQNWGGAPPRGAAPPPGAPHGPPIQQPAGVAQWDQHRYPPQQGPPPPPQQQQQPQQQQQQPPYQQVAGPPGQQPPQAPPQWAQMNPGQTAQSGIAPPGSPLRPPSGPGQQNRMPGMPAQQQQSQQQGGVPQPPPQQASHGGVPSPGLPQVGPGGMVKPPYAMPPPPSQGVGQQVGQGPPGGMMSQKPPPMPGQAMQQQPLQQQPPSHQHPHPHQHPQHQHPHQMPPNQTAPGGYGPPGMPGGGAQLVKKELIFPHDSVESTTPVLYRRKRLMKADVCPVDPWRIFMAMRSGLLTECTWALDVLNVLLFDDSTVQFFGISNLPGLLTLLLEHFQKNLAEMFDERENEEQSALLAEDADDDADSGTVMCEKLRTSGRQPRCVRSISSYN----------RRRHYENMDRSGKDGAGNGSDSEDADEGIDLGQVRVQPNPEERSLLLSFTPNYTMVTRKGVPVRIQPAENDIFVDERQKAWDIDTNRLYEQLEPVGSDAWTYGFTEPDPLDGIIDVFKSEIVNIPFARYIRSDKKGRKRTELASSSRKPEIKTEENSTEEQTFNKKRRLVSGGSSSSGAHAEGKKSKLTSEEFAQPNAEVKKEPGTADSDCRPVDMDIEAPQQRLTNGVAPCSSTPAIFDPRTTAKDEARVLQRRRDSSFEDECYTRDEASLHLVSESQDSLARRCIALSNIFRNLTFVPGNETVLAKSTRFLAVLGRLLLLNHEHLRRTPKTRNYDREEDTDFSDSCSSLQGEREWWWDYLITIRENMLVAMANIAGHLELSRYDELIARPLIDGLLHWAVCPSAHGQDPFPSCGPNSVLSPQRLALEALCKLCVTDANVDLVIATPPFSRLEKLCAVLTRHLCRNEDQVLREFSVNLLHYLAAADSAMARTVALQSPCISYLVAFIEQAEQTALGVANQHGINYLRENPDSMGTSLDMLRRAAGTLLHLAKHPDNRSLFMQQEQRLLGLVMSHILDQQVALIISRVLYQVSRGTGPIHSVEFRLLQQRQQQQLRPGPAGKQAASAGGSATVKAETASTETSSTEAKPAPAATTAVVNDENSNSSQQLPPAATFNDVSNSSTNSNSCGTASSNQTNNSTTNSSHSSSAISSQSAITVAAPSAAATGAGSATAAAIASDQQQVSKVAAAAAAAAALSNASAAAAAAAAAAAASVGPPTSSSVSAGAAVAQPAAPPPTNAGTTTAVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : . : . : . . .: * : .. * . . : :: . ::. * . * . . . .: : : . ::* . * . .. : *:: : * :.* . : . ::::: * * * * *. * .** . : .: * . . * .: .. . *:.:: . .:* . . :* : . . .**.*: .*.. * *. .::** : : : . : *: : . .* * .* . . . . . . * .. .. . * *: . *:* : . ** * *. . . . . * *. . . :. *. * ..* :...: . . .. : :: . . . . . *. . . .:.* ...* :* *.: * *: .* . : *. . * .. .. **. ** :. . . : .* * . :: :* . . .* ..*. : * :: . * .. *** .*. *.. : . * :.* . . . : . .. . . :. : . . . *.* . :. . .: . : . .* . . :. . . . : :..* .. : : . : : .* .:. :.: ::*...:.: :***:. :*:*: *:*: ** **: :: *::.::****:***: *** **:.:*.*.*.*:::* *.:*:***** :*:*:* : * :***:::** ** * : .*.:. .. *: .*. .. *.:**.** :: * *..*.*:*:: : * .. : . . . .:.*. **:.* ..: : . . :* .. . .* * .. . . ::::* . . :*. . . . . . :.*.: **. *: :..*... :.: . . .* . : *: : :* *. .: * *:. . . . .* . * . ** .. :.. *: . * .. . .** *. . . :* : : . . . : :: :: : . * * : . .* .. * : * * . :: .* .. .* * * : . ** .. :.: **:*.. : .:* :::::: ** .*:*:: *:* *:** :: . :.**::*:::****:*.*****.:*:**:**.:: *.: :***:* *::*:*:: * *:*. .: * . . * . . . * : . .. : : : : .::..: :. . : : ..*. : . *. : * *:*: : **: .: . * . . .: : .. . . * . :*** :::**:.* : : **:**:**:.:** .*.*:*:***: ::* . :* :**:*:**:* * .*. . .*::**: * . ... . ***** * :*** **:::**:*:*::* * * *. *::************.. ***.: * *..******.**:*.**.: * ****::**.******** . :.* : .: * **::* ** ** .*: **::*:*. .:. *:.*:*:: :: .* .: ::: . **:**:**** :* *** :*:* * *.***.: :* :::. *: :*. **: :.:. ", "identical_positions": 380, "similar_positions": 652, "identity": "13.4%" }, { "cls_id": "homologset.agr.MGI:1935151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCR2-1", "uniprot_id": "M0RCR2_RAT", "id": "M0RCR2-1", "name": "Krueppel-like factor 7", "aln": "MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEAT-----------------------------------------------ICEKSSAVDILLSRDKLLSETCLSLQPTSSSLDSYTAVN------------QAQLNAVTS---------------------------------------------LTPPSSPE--------------------------------------------------------------------------LSRHLVKTSQTLSA-VDGTVTLKLVAKKASLSS----------------------------------------------------VKVGGVA-AAAAVTPAGAVKSGQSDSEQGG-------------------------------------GGADTCPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGSGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JB0-1", "uniprot_id": "KLF7_MOUSE", "id": "Q99JB0-1", "name": "Krueppel-like factor 7", "aln": "MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEAT-----------------------------------------------ICEKSSAVDILLSRDKLLSETCLSLQPTSSSLDSYTAVN------------QAQLNAVTS---------------------------------------------LTPPSSPE--------------------------------------------------------------------------LSRHLVKTSQTLSA-VDGTVTLKLVAKKASLSS----------------------------------------------------VKVGGVA-AAAAVTPAGAVKSGQSDSEQGG-------------------------------------GGADTCPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTG--EKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75840-1", "uniprot_id": "KLF7_HUMAN", "id": "O75840-1", "name": "Krueppel-like factor 7", "aln": "MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEAA-----------------------------------------------ICEKSSAVDILLSRDKLLSETCLSLQPASSSLDSYTAVN------------QAQLNAVTS---------------------------------------------LTPPSSPE--------------------------------------------------------------------------LSRHLVKTSQTLSA-VDGTVTLKLVAKKAALSS----------------------------------------------------VKVGGVATAAAAVTAAGAVKSGQSDSDQGG-------------------------------------LGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTG--EKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N686-1", "uniprot_id": "A0A8M1N686_DANRE", "id": "A0A8M1N686-1", "name": "Krueppel-like factor 7", "aln": "MDVLANYSIFQELQLVHDTGYFSAMPSLEENWQQTCLELERYLQTEPKRLSDLFDEELDGLLSPS---FMKEDGD--EDLLDPLLPS-----------------------------------------------LNNPPSPS----QR----KETHSSISP-----DATLGVN------------AAQLNAVTS---------------------------------------------LTPPSSPE--------------------------------------------------------------------------LGRHLVKPTHTLSASPDGTLTLKLVARKVGLSS----------------------------------------------------AKL--VAAHPVPLSPQHGSTGTQSDGEQGGTCT----------------------------------IGVGDMAENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTG--EKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MR37-1", "uniprot_id": "KLFL_DROME", "id": "Q8MR37-1", "name": "Krueppel-like factor luna", "aln": "MDILPSGNIFSELERICTTGYYSSQPSIEDQWQQTCYELERYLRDEPKLQKKMHSNLDNPWDIFSTPARLLEELKIKEQHLDTISTTSSVSSNCSGTSWDSNGSQALSCSVLVKQERIDEEDDDVGCDDKLSVLLAAPPSAISPNPSIGSAGNMTPTSISNSSSISSSNSHSNSNGNTTGSSNIIASPLSSLGSGSTITVSSRNSSAPGIKVRVVQAKNHPGSNARMHLGHVQDFVLPTLTPPSSPESNLRSHNYAQQLEANDLAALIQQQQQQQQQQQQQQQQQQLNPQPGNSTPATAILRFTSQSNPTMTQLQQQQQQLAVQHLSISPQALGHSNIGSNSPKSSSSSSSNSSNSSSSSHSSSSSISGSSDQPTHSNIPRSTIVRLTTANGKPGAAGISLARVIQMQNNGNANVAAVLSAAANSGSSNSNSNSSSSNTSSNSINTATPQQQVLSQRSEKSANGSSKPHHPRQHHSDHSPDAKRRIHKCQFLGCKKVYTKSSHLKAHQRTHTG--EKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRHM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.. .**.**: : ***:*: **:*: ***** ******: **: .. ..: : * : *. : * .: .: : .*. . . * *:. .: * : *.:: * ******** :** ..::*. *: : * : . . ** : * .. ::. . :*:.:... .: *:*:*:*** **:****************** ************************************.:******************:", "identical_positions": 133, "similar_positions": 73, "identity": "23.25%" }, { "cls_id": "homologset.agr.MGI:1935159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61604-1", "uniprot_id": "CH10_HUMAN", "id": "P61604-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGE-IQPVSVKVGDKVLLPEYGGTKVVLD--DKDYFLFRDGDILGKYVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26772-1", "uniprot_id": "CH10_RAT", "id": "P26772-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGGKGKGGE-IQPVSVKVGDKVLLPEYGGTKVVLD--DKDYFLFRDGDILGKYVD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI95-1", "uniprot_id": "Q9JI95_MOUSE", "id": "Q9JI95-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QAFRKFLLLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGGKGKSGE-IEPVSVKVGDKVLLPEYGGTKVVLD--DKDYFLFRDSDILGKYVN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JVI0-1", "uniprot_id": "A0A0G2JVI0_RAT", "id": "A0A0G2JVI0-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QVFRKSRLLPDRVLAERSVVVTVAKGGIMLPETTQGKVLQATIVVVGSGMKEKSEE-IQPVSVKVGDKVLLLEYGGTKAVLD--DKDYFLFRDGDILRKYVN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU35-1", "uniprot_id": "Q9VU35_DROME", "id": "Q9VU35-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MA---AAIKKIIPMLDRILIQRAEALTKTKGGIVLPEKAVGKVLEGTVLAVGPGTRNASTGNHIPIGVKEGDRVLLPEFGGTKVNLEGDQKELFLFRESDILAKLE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFN5-1", "uniprot_id": "Q9VFN5_DROME", "id": "Q9VFN5-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MS---NVIKKVIPMLDRILIQRFEVKTTTAGGILLPEESVPKEMQGVVVAVGPGARNPAGAGHLSVGVKEGDRVLLPKYGGTKVDMD-DKREYVLFRESDILAKLE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38910-1", "uniprot_id": "CH10_YEAST", "id": "P38910-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MSTLLKSAKSIVPLMDRVLVQRIKAQAKTASGLYLPEKNVEKLNQAEVVAVGPGFTDANGNKVVPQ-VKVGDQVLIPQFGGSTIKLG-NDDEVILFRDAEILAKIAKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. : **:* :* . : : .*: *** * :. ::.**.* . ** **:**: ::**:. : . : .***:.:** * ", "identical_positions": 27, "similar_positions": 31, "identity": "25.0%" }, { "cls_id": "homologset.agr.MGI:1935212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5H4-1", "uniprot_id": "PCDG1_HUMAN", "id": "Q9Y5H4-1", "name": "Protocadherin gamma-A1", "aln": "MKIQKKLTGCSRLMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGEVTYSFHNVDHR-VAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGAGLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILADLGSLEPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRWHKSRLLQASGGGLASMPGSHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKKGFLSAPQSLLEDKKEPFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTG--------TWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSAR------YGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A6YW27-1", "uniprot_id": "A0A0A6YW27_MOUSE", "id": "A0A0A6YW27-1", "name": "", "aln": "MAIPEKLTGWSLLVLVCLSLELLLEAGAGNIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHS-VVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLVTDINDNPPVFEQDSYSVYIPENNPRGASIFSVKAQDADHNENALVTYALVEDTIQGVPLSSYFSINSDTGVVYALQSFDYEQFRDLQLRVMAHDSGNPQLSSNVSLSLFMIDQNDNAPEILYPVLPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNSWLSYRLLKASEPGLFSVGLHTGEVRTARALLERDALKQSLVVAVQDHGQPPLSTTVTFTIAVADSIPDLLADLGSMGTPADPQDSDLTLYLVVAVAVVSCIFLAFVIVLLVLKLRHWYSSRLLQTEANGLTGLPASNFVGVDGVHAFLQTYSREISLTADSRKSHLIFPQPNYADTLISHESCEKQEFLSAPQSLLEDKEEIFSQVNL------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N6D6-1", "uniprot_id": "A0A8M1N6D6_DANRE", "id": "A0A8M1N6D6-1", "name": "", "aln": "----MKTMLDAMIQHSVLILTLLVYIARGQVSYSIPEEMAKGSMVGNIAQDLGLDLQRLKSGKARIFSRDSTEYIELNRNTGLLLIKEKMDRESLCAKTTPCALHLQMILDNPMELYTITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKFRLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQ-TGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFTHEKQYNDS-LTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIPYYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLGGQNVLVVDPSFAETMKHTIKKNSSIDDLQSTESQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEATATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6Q0-1", "uniprot_id": "A0A8M1N6Q0_DANRE", "id": "A0A8M1N6Q0-1", "name": "", "aln": "------MAFFVMWHGAVFFMILSRYAVKGQISYSIPEEIPKGSIVENNSQGLGLDLKRLNSGKARIFAGDNRRFVGLNKEKGILLTEEKIDREALCAKTTPCASHLQLILENPMQKYDVTVEIIDINDNAPSFPKGEIRFEISETAVTGARFMLENPIDLDVGTNSHLSYSLKPTDNFILSSQGQTDGDKNMEMVLQKALDRENKEKLSLMLTAVDGGEPSLTSTVRIHVTVLDANDNPPVFSQRVYKATFAEITPKDTVIASVSASDADEGSNAIITYYMSSTGD--VNDLFTVDTRSRDIRLKGSADFEKASRYQFNIQARDQGGLSDSCKVIIDLTDINDNKPIISIVSMSNSISEQSRPGTVVAMLNVNDFDSGMNGRVHCYRNDNIPFTIAS-SSSFFSLQTEQELDREKEAEYNISVICSDEGVPALSSSVSLRVQISDVNDNAPVFEKSNYEAFVVENNTPGLSIFTVKASDADWNQNARVSYILEDSIVNGVSISSYVSVHPESGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDHNDNAPQVLYPVQ-TGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFTHEKQYNDS-LTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIPYYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLGRQNVLVVDPSFTETMQHTIKKKCSIDGLRITKSQKPPNTDWRFPPNQRPGPSGQHRFHTLQQRWTPYEKSRAGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANE--------ERNTHRFETSGRK------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 276, "similar_positions": 286, "identity": "28.72%" }, { "cls_id": "homologset.agr.MGI:1935216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XY4-1", "uniprot_id": "PCDG4_MOUSE", "id": "Q91XY4-1", "name": "Protocadherin gamma-A4", "aln": "-------------------------------MAAP-YKSDRRGLIWICIFLGSLCDIRAEQIRYSVPEELERGSVVGNLAADLGLEPGKLAERGVRIVSRGKTQLFALNPRSGSLVTAGRVDREGLCDRSPKCTANLEILLEDKVRILAIEVEIIDVNDNAPSFGAQQREIKVAESENPGTRFPLPEAFDLDIGVNALQGYQLSSNDHFSLDVQSGPDGIKYPELVLENALDREEEAVHHLVLTAFDGGDPVRSGTATIQVTLVDTNDNAPVFTQPEYHISVKENLPVGTRLLTIKATDPDEGVNGEVTYSFRNVREK-ISQLFQLNSLTGDITVLGELDYEDSGFYDVDVEAHDGPGLRARSKVLVTVLDVNDNAPEVTVTSLTSSIQEASSPGTVIALFNVHDSDSGENGLVTCSIPDNLPFRLEKTYGNYHRLLIHRTLDREEVSDYNITITATDQGTPPLSTETYISLQVVDINDNPPTFTHASYSAYIPENNPRGASILSITAQDPDSGENAQVIYSLSEDTIQGAPMSSYVSINSNTGVLYALRSFDYEQFQDLKLLVTARDSGTPPLSSNVSLSLSVLDQNDNTPEILYPTIPTDGSTGVELTPRSADPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVTVQDHGQPPLSATVTLTIAVSDNIPDILADLVNINAPIDQEDSDITLYLVVAVAAVSCVFLAFVIVLLIHRLRRWHSTRLLQAAGNGLSSLPASHFVGVDGVHAFLQTYSHEVSLTADSGKSHLIFPQPNYADTLISQESCGKSDPLLVSQDLLEIKGDSSLQQAPPNTDWRFSQAQRPGTSGSQ------------NGDETGTWPNNQ--FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5G9-1", "uniprot_id": "PCDG4_HUMAN", "id": "Q9Y5G9-1", "name": "Protocadherin gamma-A4", "aln": "MHFILDPEDPGAPQASTEGKPKHRRLRGGVVMAAPPARPDHTRLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRKVRDK-ISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHDGPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAEGSRLAGVPASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFSQPSYADTLISRESCEKSEPLLITQDLLETKGDPNLQQAPPNTDWRFSQAQRPGTSGSQ------------NGDDTGTWPNNQ--FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6D6-1", "uniprot_id": "A0A8M1N6D6_DANRE", "id": "A0A8M1N6D6-1", "name": "", "aln": "-----------------------------------MKTMLDAMIQHSVLILTLLVYIARGQVSYSIPEEMAKGSMVGNIAQDLGLDLQRLKSGKARIFSRDSTEYIELNRNTGLLLIKEKMDRESLCAKTTPCALHLQMILDNPMELYTITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKFRLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYP-VQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFTHEKQYNDS-LTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIPYYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLGGQNVLVVDPSFAETMKHTIKKNSSIDDLQSTESQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEATATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6Q0-1", "uniprot_id": "A0A8M1N6Q0_DANRE", "id": "A0A8M1N6Q0-1", "name": "", "aln": "-------------------------------------MAFFVMWHGAVFFMILSRYAVKGQISYSIPEEIPKGSIVENNSQGLGLDLKRLNSGKARIFAGDNRRFVGLNKEKGILLTEEKIDREALCAKTTPCASHLQLILENPMQKYDVTVEIIDINDNAPSFPKGEIRFEISETAVTGARFMLENPIDLDVGTNSHLSYSLKPTDNFILSSQGQTDGDKNMEMVLQKALDRENKEKLSLMLTAVDGGEPSLTSTVRIHVTVLDANDNPPVFSQRVYKATFAEITPKDTVIASVSASDADEGSNAIITYYMSSTGD--VNDLFTVDTRSRDIRLKGSADFEKASRYQFNIQARDQGGLSDSCKVIIDLTDINDNKPIISIVSMSNSISEQSRPGTVVAMLNVNDFDSGMNGRVHCYRNDNIPFTIAS-SSSFFSLQTEQELDREKEAEYNISVICSDEGVPALSSSVSLRVQISDVNDNAPVFEKSNYEAFVVENNTPGLSIFTVKASDADWNQNARVSYILEDSIVNGVSISSYVSVHPESGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDHNDNAPQVLYP-VQTGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFTHEKQYNDS-LTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIPYYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLGRQNVLVVDPSFTETMQHTIKKKCSIDGLRITKSQKPPNTDWRFPPNQRPGPSGQHRFHTLQQRWTPYEKSRAGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANE--------ERNTHRFETSGRK------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 301, "similar_positions": 315, "identity": "30.34%" }, { "cls_id": "homologset.agr.MGI:2135267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MH9-1", "uniprot_id": "BBS2_RAT", "id": "Q99MH9-1", "name": "BBSome complex member BBS2", "aln": "MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQAGKVFIHNPHMRSQHFSTSRVFQSPLESDVSLLNINQTVSCLGAGVLNPELGYDTLLVGTQTSLLAYDIYNNSDLFYREVADGANALVLGTLGDIAPPLAIIGGNCALQGFDHEGNDLFWTVTGDNVHSLALCDFDGDGKSELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTARYWRIKSKNHAMSIHAFDINSDGVCELITGWSNGKVDARSDRTGEVIFKDNFSSAVAGVVEGDYRMDGHVQLICCSVDGEIRGYLPGTAEMKGNLLDTSVEQGLIRELSQKKQNLLLELRNYEENTKAELSSPLNEADGQKGIIPANTKLHTALSVNLGNDAQDAHAELRISTSNDTIIRAVLIFAEGIFAGESHVVHPSTHNLSSSIRVPITPPKDVPVDLHLKTFVGYRSSTQFHVFELIRQLPRFTMYALTSPDAASEPVSFVNFIVVERAQRMVTWLNQNFLLPEDSNIQNAPFHVCFTSLRNGGQLYIKMKPSGEITVNTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLLKVDEYHSVHQKLSANMADNSNLIRSLLVRAEDARLMRDMKTMKTRYMELYDLNKDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVISACRDAIRSNNINTLFRIMRVGTAPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWF6-1", "uniprot_id": "BBS2_MOUSE", "id": "Q9CWF6-1", "name": "BBSome complex member BBS2", "aln": "MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQAGKVFIHNPHTRSQHFSASRVFQSPLESDVSLLNINQTVSCLGSGVLNPELGYDTLLVGTQTSLLAYDIYNNSDLFYREVSDGANAIVLGTLGDIAPPLAIIGGNCALQGFDHEGNDLFWTVTGDNVHSLALCDFDGDGKTELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTARYWRIKSKNHAMSIHAFDINSDGVCELITGWSNGKVDARSDRTGEVIFKDNFSSAVAGVVEGDYRMDGHVQLICCSVDGEIRGYLPGTAEMKGNLLDTSVEQDLIRELSQKKQNLLLELRNYEESTKAELSSPLNEADGQKGIIPANTRLHTALSVNMGNDLQDAHAELGISTSNDTIIRAVLIFAEGIFVGESHVVHPSIHNLSSSLRVPITPPKDVPVDLHLKTFVGYRSSTQFHVFELTRQLPRFTMYALTSPDAASEPVSYVNFSVAERTQRMVTWLNQNFLLPEDSNVQNSPFHVCFTSLRNGGQLYIKMKQSGEITVNTDDIDLAGDIIQSIASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADNSNLIRSLLVRAEDARLMRDMKTMKSRYMELYDLNKDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVISACRDAIRSNNINTLFRIMRVGTAPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXC9-1", "uniprot_id": "BBS2_HUMAN", "id": "Q9BXC9-1", "name": "BBSome complex member BBS2", "aln": "MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQSPLESDVSLLSINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGANAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKSKNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMDGHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAEGIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPRFSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98SP7-1", "uniprot_id": "BBS2_DANRE", "id": "Q98SP7-1", "name": "BBSome complex member BBS2", "aln": "MLVPIFTLKLNHKINPRMVAIGKYDGIHPCLTAATQAGKVFIHNPHTRAQRPTAHRLSQSTQDSDISLLNINQSVSCLTAGTLGPKSTGDTLLVGSQTNLLAYDVHDNTDVFYKEVTDGANAIVLGKLGDIQSPLAIIGGNCALQGFDYEGNDLFWTVTGDNVRSLVLCDFTADGKNELLVGSEDFDIRVFKEDELVTEMAENETVTSLCHMHGSRFGYALANGTVGVYDRTARYWRIKSKNHAMSIHAFDLNADGVVELITGWSNGKIDARSDRTGEVIFKDNFSSSVAGVVEGDYRMDGQIQLICTSVEGEVRGYLPASKEMKGNLMDSSIEQDLIRELSQRKQNLMLELRNYEENAKALPG--LSEGESKMGVIPANTQLQTALSVRRASESQKAHIELNISTPNETIIRAVLIFAEGIFEGESHVVHPSAQNLSGCVRVPIIPPKDIPVDLHIKAFVGGKTSTQFHVFEITRQLPRFSMYDLNVDPSAPEPTGKVTFCINDRPQRVVMWLNQNFLLPEGIDSPD----VTFSALRGGGLLRISLQTSGEITLRTDDIDLAGDLVQSLASFLAIEDLQAESDFPVYFKELRATLTEVDEFHSVHQKLTAAMADHSNYIRNMLVQAEDARLMGDWRNMKKRYIELYDLNRDLVNEYKIRSNNHNALLARLKSVNQAIQRAGRLRVGKPKSQVITACRDAIKNNNINALFKIMRAGTTSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:*****.***.*******:*** ****:****:********* * *: :: *: **. :**:***.***:**** :*.*.*: *:****:**.*****:::*:*:**:**:*****:***.**** .**************::**.***********.**.**** .***.******************:*:**:*.* ***** *:********:********:*:******************:*:*** **********:******************::************::**** **:**:*****.: **:***:*:* **.*******:****:********.:** . *.*.:.: *:*****:*:*:*** ..: * ** ** ***.*:************** ********* :***..: :** ****:*****:*:*** ::******** ******:** *. .*.** . *.* : :*.**:* **.*******. . : * *::**.** * *.:: *****:.*********::**:***:******.*:******:*** .* :***:*******:* ***:** **.:** ******* * :.**.**:******:**:* ****.***. **..**:*****************.***:******:.****:**:***.**:.*", "identical_positions": 507, "similar_positions": 148, "identity": "70.32%" }, { "cls_id": "homologset.agr.MGI:2135272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84889-1", "uniprot_id": "VANG2_RAT", "id": "P84889-1", "name": "Vang-like protein 2", "aln": "MDTESQYSGYSYKSGHSRSSRK--------------------HRDR-------RDRHRSKSRDGS-RGDKS---VTIQAPGEPLLDNE---STRGDERDDNWGETTTVVTG-TSEHSISHDDLTRIAKDMED-SVPLDCSRHLGVAAGAILALLSFLTPLAFLLLP--------------PLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVISYWLFYGVRILD---------ARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLA---KKVSG-FKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQ----KNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZD4-1", "uniprot_id": "VANG2_MOUSE", "id": "Q91ZD4-1", "name": "Vang-like protein 2", "aln": "MDTESQYSGYSYKSGHSRSSRK--------------------HRDR-------RDRHRSKSRDGS-RGDKS---VTIQAPGEPLLDNE---STRGDERDDNWGETTTVVTG-TSEHSISHDDLTRIAKDMED-SVPLDCSRHLGVAAGAILALLSFLTPLAFLLLP--------------PLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVISYWLFYGVRILD---------ARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLA---KKVSG-FKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQ----KNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULK5-1", "uniprot_id": "VANG2_HUMAN", "id": "Q9ULK5-1", "name": "Vang-like protein 2", "aln": "MDTESQYSGYSYKSGHSRSSRK--------------------HRDR-------RDRHRSKSRDGG-RGDKS---VTIQAPGEPLLDNE---STRGDERDDNWGETTTVVTG-TSEHSISHDDLTRIAKDMED-SVPLDCSRHLGVAAGATLALLSFLTPLAFLLLP--------------PLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVVSYWLFYGVRILD---------ARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLA---KKVSG-FKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQ----KNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UVJ6-1", "uniprot_id": "VANG2_DANRE", "id": "Q8UVJ6-1", "name": "Vang-like protein 2", "aln": "MDNESQYSGYSYKSSHSRSSRK--------------------HRDR-------RDRHRSKSRDSSSRGDKS---VTIQAPGEPLLDAE---STRGDDRDDNWGETTTVVTG-TSEHSVSNEDLTRASKELED-SSPLECRRFAGPIVSGVLGLFALLTPLAFLLLP--------------QLLWRDSLEPCGTPCEGLYVSLAFKLLVLLISSWALFLRPSRSTLPRFFVFRCLLMALVFLFVASYWLFYGVRVLE---------PRERDYRGIVGYAVSLVDALLFIQYLALVLLEVRHLRPAFCLKVVRTTDGASRFYNVGHLSIQRAAVWVLDHYYTDFPVYNPALLNLPKSILS---KKMSG-FKVYSLGEENSTNNSTGQSRAMIAAAARRRDNSHNEYYYEEAEMDRRVRKRKARLVVAVEEAFTHIKRLQDDEAAASPKHPREVMDPREAAQAIFAPMARAMQKYLRTTRQQPYHSMESIISHLQFCITHNMTPKAFLERYLTPGPTMQYQRENGRGRQWTLVSEEPVTAALRQGLVFSLRRLDFALVVTVTPLPFLNLGEEFIDPKSHKFVMRLQSETSV---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEN4-1", "uniprot_id": "A0A0B4KEN4_DROME", "id": "A0A0B4KEN4-1", "name": "Vang-like protein", "aln": "MENESVKSEHSGRSRRSRNHNNNGGGGGGGGGGGGGSVNNGYHRERDRSRHSHRSTHSSKSAKGFQRGDMAPYQTSVNMTGDGSHDGQEVIEVQILPQDENWGENTTAVTGNTSEQSISMEDINNMWHRESDKGFSFACRRYVESSFYFLLGCGAFFSPVAMVVMPYVGFFPSAFDHPEITQTVRTQLLACSEQCKGQLVSLAARLLLLAIGLWAVFMRRTSATMPRIFLYRALVLLLVTICTFAYWLFYIVQVTNGAKIVVETGGDAVDYKSLVGYATNFVDTLLFIHYVAVVLLELRHQQPCYYIKIIRSPDGVSRSYMLGQLSIQRAAVWVLQHYYVDFPIFNPYLERIPISVSKSQRNKISNSFKYYEVDGVSNSQQQS-QSRAVLAANARRRDSSHNERFYEEHEYERRVKKRRARLITAAEEAFTHIKRIHNEPA------PALPLDPQEAASAVFPSMARALQKYLRVTRQQPRHTFESILKHLAHCLKHDLSPRAFLEPYLTESPVMQSEKERRWVQSWSLICDEIVSRPIGNECTFQLIQNDVSLMVTVHKLPHFNLAEEVVDPKSNKFVLKLNSETSVXHHHNAPPINTPTHSNQTQSSYLHVFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 221, "similar_positions": 191, "identity": "35.93%" }, { "cls_id": "homologset.agr.MGI:2135283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C5H6-1", "uniprot_id": "TUTLA_RAT", "id": "P0C5H6-1", "name": "Protein turtle homolog A", "aln": "-------------------------------------------------------------MIWCLRLTILSLILSQGADGRRKPEVVS------------------------------------------------VVGRAGESAVLGCDLLPP--------AGRP---PLHVIEWLR----FGFLLPIFIQFGLYSPRIDPDYVGRVRLQTG------ASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVALGSPQPYVTWKFRGQDLGKGQGQVQVRNGT-LWIRRVERGSAGDYTCQASSTEGSVTHTTQLLVLGPPVIVVPPNNNTVNASQDVSLACRAEAYPANLTYSWFQDRINVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFPHPPSASAYLTVLYPAQVTVMPPETPLPIGMRGVIRCPVRANPPLLFVTWTKDGQALQLDKFPGWSLGPEGSLVIALGNEDALGEYSCTPYNSLGTAGSSPVTRVLLKAPPAFIDQPKEEYFQEVGRDLLIPCSAR---GDPPPIVSWAKVGRGLQG----QAQVDSNNSLILRPLTKEAHGRWECSARNAVAHVTISTNVYVLGTSPHVVTNVSVVPLPKGANVSWEPGFDGGY--LQRFSVWYTPLAKRPDRAHHDWVSLAVPMG-ATHLLVPGLQAYTQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAVPRLPPTEMPP------------PLSPPRGLVAVRTPRGVLLHWDPPELIPERLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPSNIANISTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAACLMNRRRAARRHRKRLRQDPPLIFSPRGRSGPHSAPGSDSPDSVTKFKLQ------------------------GSPVPSLRQSLLWGEPARPPSPHPDSPLGRGPLP----LEPICRGPDGRFVMGPTVAPPQEKLCLERSEP------------------------------------------------------RTSAKRLAQS----------------------LDCSS------------------------------------------------------------------------------------------------------------------------------------SSPSGVPQPLCIT--------------------------DISPVGQPPAAMPSP-------------------------------------------------------------------------LP------------------------------GPGP---------------------------------------------------------------------------------------------------------------------------------------------------LLQYLSLPFFREMNVDG------------------------------------------------------------------------------------------DWPPLEEPTPASP-------------------------------------PDFMGSH---------------------------------PCPTSS------------------------------------------------------------------------------------------------FLPPP------------DSPPTNLRAVLPG-------------TLMGVGVSSEPP-------------YTALAD-----------------------WTLRERVLPGLLS---AAPRGSLTSQSSGRGSASFLRPPSTAPSAGGS-YLSPAPGDTSSWASGPE-------RWPRREHVVTVSKRRNTSVDENYEWDS-EFPGDMELLETWHPG-----LASSR----AHPELEPELGVKTPEKSCLLNTTHAPGP--------------EARCAALREEFLAFRRRRDATRARLPVCQQSISYPEQATLL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05BQ1-1", "uniprot_id": "TUTLA_MOUSE", "id": "Q05BQ1-1", "name": "Protein turtle homolog A", "aln": "-------------------------------------------------------------MIWCLRLTVLSLIISQGADGRRKPEVVS------------------------------------------------VVGRAGESAVLGCDLLPP--------AGHP---PLHVIEWLR----FGFLLPIFIQFGLYSPRIDPDYVGRVRLQTG------ASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVARGSPQPYVTWKFRGQDLGKGQGQVQVQNGT-LWIRRVERGSAGDYTCQASSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACRAEAYPANLTYSWFQDGVNVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFLHPPSASAYLTVLYPAQVTVMPPETPLPTGMRGVIRCPVRANPPLLFVTWTKDGQALQLDKFPGWSLGPEGSLIIALGNENALGEYSCTPYNSLGTAGPSPVTQVLLKAPPAFIDQPKEEYFQEVGRELLIPCSAR---GDPPPIVSWAKVGRGLQG----QAQVDSNNSLVLRPLTKEAQGRWECSASNAVARVTTSTNVYVLGTSPHVVTNVSVVPLPKGANVSWEPGFDGGY--LQRFSVWYTPLAKRPDRAHHDWVSLAVPIG-ATHLLVPGLQAHAQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAAPGLPPTEIPP------------PLSPPRGLVAVRTPRGVLLHWDPPELIPGRLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPSNVANISTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAACLMNRRRAARRHRKRLRQDPPLIFSPRGKSGSHSAPGSGSPDSVTKFKLQ------------------------GSPVPSLRQSLLWGEPARPPSPHPDSPLGRGPLP----LEPICRGPDGRFVMGPTVAPSQEKLCLERSEP------------------------------------------------------RTSAKRLAQS----------------------FDCSS------------------------------------------------------------------------------------------------------------------------------------SSPSGVPQPLCIT--------------------------DISPVGQPLAAVPSP-------------------------------------------------------------------------LP------------------------------GPGP---------------------------------------------------------------------------------------------------------------------------------------------------LLQYLSLPFFREMNVDG------------------------------------------------------------------------------------------DWPPLEEPTPAPP-------------------------------------PDFMDSQ---------------------------------PCPTSS------------------------------------------------------------------------------------------------FLPPP------------DSPPANLRAVLPG-------------TLMGVGVSSEPP-------------YTALAD-----------------------WTLRERVLPGLLS---AAPRGSLTSQSSGRGSASFLRPPSTAPSAGGS-YLSPAPGDTSSWASGPE-------RWPRREHVVTVSKRRNTSVDENYEWDS-EFPGDMELLETWHPG-----LASSR----THPELEPELGVKTPEESCLLNPTHAAGP--------------EARCAALREEFLAFRRRRDATRARLPAYQQSISYPEQATLL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2J2-1", "uniprot_id": "TUTLA_HUMAN", "id": "Q9P2J2-1", "name": "Protein turtle homolog A", "aln": "-------------------------------------------------------------MVWCLGLAVLSLVISQGADGRGKPEVVS------------------------------------------------VVGRAGESVVLGCDLLPP--------AGRP---PLHVIEWLR----FGFLLPIFIQFGLYSPRIDPDYVGRVRLQKG------ASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGT-LRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPKEEYFQEVGRELLIPCSAQ---GDPPPVVSWTKVGRGLQG----QAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGY--LQRFSVWYTPLAKRPDRMHHDWVSLAVPVG-AAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPP------------PLSPPRGLVAVRTPRGVLLHWDPPELVPKRLDGYVLEGRQGSQGWEVLDPAVAGTETELLVPGLIKDVLYEFRLVAFAGSFVSDPSNTANVSTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAGCLLNRRRAARRRRKRLRQDPPLIFSPTGKSAAPSALGSGSPDSVAKLKLQ------------------------GSPVPSLRQSLLWGDPAGTPSPHPDPPSSRGPLP----LEPICRGPDGRFVMGPTVAAPQERSGREQAEP------------------------------------------------------RTPAQRLARS----------------------FDCSS------------------------------------------------------------------------------------------------------------------------------------SSPSGAPQPLCIE--------------------------DISPVAPPPAAPPSP-------------------------------------------------------------------------LP------------------------------GPGP---------------------------------------------------------------------------------------------------------------------------------------------------LLQYLSLPFFREMNVDG------------------------------------------------------------------------------------------DWPPLEEPSPAAP-------------------------------------PDYMDTR---------------------------------RCPTSS------------------------------------------------------------------------------------------------FLRSP------------ETPPVSPRESLPG-------------AVVGAGATAEPP-------------YTALAD-----------------------WTLRERLLPGLLP---AAPRGSLTSQSSGRGSASFLRPPSTAPSAGGS-YLSPAPGDTSSWASGPE-------RWPRREHVVTVSKRRNTSVDENYEWDS-EFPGDMELLETLHLG-----LASSR----LRPEAEPELGVKTPEEGCLLNTAHVTGP--------------EARCAALREEFLAFRRRRDATRARLPAYRQPVPHPEQATLL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDD3-1", "uniprot_id": "A0A8N7TDD3_DANRE", "id": "A0A8N7TDD3-1", "name": "", "aln": "------------------------------------------------------------MVQKKLWLLNVSVAVALSLLRLTLSTEPV------------------------------------------------VQGRVGGFAELGCSLTPPSE-----GATTPNLFPLHVVEWVR----LGYNVPILIKFGSYTPRVHPNYKGRVSLSRG------ASLMVEKLTLEDEGWFECRILLLDRTS--DEFQNGTWNFLSITAPPVFIKTPPPFLEVLLGESLTLHCDAHGNPKPTIIWRKYLSAAEK-QEEIQVLNET-LSLSKVTRETAGIYKCHVSNSEGNLTHSTQLQVKGPPIIIIAPEDTTMNMSQDAVLQCQAEAYPSNLTYEWWKQGQNVYHIEILKSRVKILVDGTLLISALIPDDSGNYTCRPTNGLMTPPAASAYLTVKHPARVVRMPRETYLPMGMGGKIPCPVQAEPPMLYVNWTKDGASLNLEQYPGWMVNSEGSVFITAANDDAVGMYTCTAYNSYGTMGQSEPTKVILKDPPSFRVSPRAEYLQEVGRDLVIPCQSQ---GDPSPNITWIKVGPAPRS----PFTVLSNGSLFLRPLSKDHQGTWECLASNRVATVSVATTILVLGTSPHAVTSVSVDPGIGQANVSWEAGFDGGY--TQRFTVWVKPTVRG----KHEWASIPVPTS-KTSLLVTSLQPATSYQFSVLAQNKLGSGPFSEIVTIKTLAPPTESPT----VLTTMA------------VLSPPTLLSANRTSLGVLLQWVPP--LEESLTSFALQAKRGKGEWVTIDREIAVNMTELIVQGLVKDSKYELRLLSCQDKLVSVPSDSVLISTEGMEMYPAAPSLLAFVPEPLLAGVIGGVCFLFVAIILSLVTACVMNSKRRQRRQKK--RDDIPSAFQKS--SAPQANSPSDSPDSLLKLKLCPPLNFFPNSSSSDRSDRSSFDKASRSEYQDQKKQLLSSSSPPPHYTQFESHFGGTPSPTPA-IESISRSPDGRFIIQPDLENFKKNLKKEFPQSPSRGSGRGSSNGSFKESNQSNSARSETNAQTEMPSALTVDHPHLERPPHSPGRVRAMARNFSRHGCFYSDDEHGGSEALLERASFYSDCSEKKASDSLKKYRGAIHREEIFPSLTRRTRERDRMLQQAHYQPINGDSQLTEPSTMITQLDGERERDNLSKCLKLAKEREQMEKELEHYTASRRVQAHEREQRRAKSASPLRKWTGVESQDPIWKPQDIQLRQKSRPSSLAQHVSDNRRGCYFGNTSSPMERHPSSSSSYIQWDISPVTSPTSLVPVQSLSEGNTPHSLYPNMRQQAIPNVEGSSATGISHSPATQYTSLSIFTPHRESSPSRSSLHGAQARYSESQLEEELPNRTLVEESWLAERKIEKESPPFRSKSPAHLSPQPSELHQVLEGADRDANSHYLDPRSQDVTDKEEEGIVQKDRLLSRNPSGCSTLPYDHKRGAKEKVIDDSLSILPYNEQEKEGIRARSRKSDKCVLTESPSRISPLTLLENEAESDQSNFSRMSESMKVKLASQPARMSPLQTST-----ILEYLSLPGFIEMSVDDPVEVTEPSESVEPNVELESGTMLRVEPDVVPKSWEKHSQDLSGTNGVVHDHGTQNVPMEKPKPEDISEPLPQLEARDRCVKSGTSDKSNKRFPPLKEKNKSSEPLLSQSSGSQREQFIQHGPAQTLINTAKSMAAIVSKCPDFISQQYQRPQIHSDSTNMISSRINQAPVPFMKKSVSIGPCRTLSGAGQPRPFLRKSISLGSRYEHSELPRPYFSETCYRDQFPNPDIRLKSYSLGRTPSHYYPISGPSWRGSVPYQPPHSYSLERHHIERSGMTPPYQTTFVPNPSRQMEPSLPSRRESDPRRQAAVFPDSSRWPLSYQETLRSVQHKYVPQDPPRPFGPNRSLARVDYMHPAEPRRCPPRPFLPRGYSWPSPHHPSFPLREHDFPRELDKGMGAVRGCAETERDG-GRASYASQSSGRGSVGPYGHLRQSLSITPTLLSSPETTEESERHRADKDTRERRSKRRNTSVDESYEWDAVEYSMDHDVLEAMKVERPHAAFGRGRGFRPERPRSTAGLQDLQSKRLYSVSPPLVSQPP----QHRYSRSLSEARFNALRQEFQEYRRAQESCTQDPCIPHDPDSDSSSALL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B6E7-1", "uniprot_id": "A0ACD6B6E7_DANRE", "id": "A0ACD6B6E7-1", "name": "", "aln": "-------------------------------------------------------------MRLKNLPLLEVIVAVLCLFNDTSAAEEH------------------------------------------------VRAKKDSSAVLPCSLPAPQKDSSAS---------QYVIEWVR----QGFDTPIFMQLGVH-PRVHPDYDGRVSLFGG------TSLQMSGLQLEDEGWYECRILPLDQTTEEAGSS-GSWTRLFVTAPPVLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKDG-APIKPQHKVKMVNGS-VSFHAVSREAAGQYQCYSSNSEGNATHVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADPPNMTYVWQRQGVDIYHIDSLKSRIKVIVDGTLLISRLAPEDSGNYTCMPTNGLPVSPSASAVLTVQHPAQVIQMPKLTFLPTGMRGAIVCPVRAEPPLSHIDWIKDGKPLDLGMYPGWTLASDGSIVIATVNDDAAGVYICTPYNSFGTTGQSEPTTVILQDPPSFKVSPRNEYRQDVGTMLVIPCQMV---GNPAPKVNWRKIGAATRS----LFTLAGNGSLILHPLSKDHQGEWECSSSNRVATVSIKTMVLVLGTSPHAVSSVSVIPGTNQANVSWVAGFDGGY--TQTFTVWYKQVSAGRTEEKQEWLSFSDLST-ENSLLVTNLLPATEYQFSVMAQNKIGTGPFSEIITVTTLDA-----------LPVVA------------KLEPPTNLSVNKSSEGFLLLWSAPHSKSPPIDSFVVQSRLEGGEWDNLKEDISPAESKIFLPGLCKDCKYELRLLSQHGDQLSMPSPSISVSTFGMNMRPASSRLLDFP-NHIMAGVMGGVGLLCLVLVLTLAIVCFISYKRSRRRRQNIKDLPPAMDKNASVNIPDDTLKQRLLPAHPLSTSSSASN-------------HSSLDKFSHSDFHDLRQHHLPQANPPSHHSLPESHLQLSSLAPVSSVEFIHRGPDGRFVVHPGEGDSNFSSQIKRNPN--QNSHQASDGSRSFRIQKSQSLRSYMDEQRRPPFVLSVDLPPFGSNIPSSSRTRAMVKHLSLNG-HYMPILEKEIMDVPDQTSLSSDCSDSYLYAHSESTLGQ--------------------------KSPKRDTNHSTASTLVLQMEHEREQGNLSRCLTLAREREELERELRKYTVDLNSSSHEQTDDEYGN------------------------LWKTQEASTPQVKYQTMRQSILSENTG---MFKRRAASCIPWEERHKISSANLLPLHKSYEKDIKYRQNQGYN-------------SVQRSRYQRSRSLDREEHRKSHTWDQRRSKTPVESSRYCVMDELIYKLENPQTCEGPRARMTSSRSQHYFDPCIYPSPGDQQWRTVQR-------------------------------------------------------------------------------------------------------------------------------------S-----NREIHPVGDYSEMSVDGP-----------------------------------------------------------------------------------------DFESQHANSRSTVRSEHSYETLDYDR-----------PRLSELEMDRLVKPGHVSSRKDKKLNN-------------------------WSSKTESPMNVSERMPQRTNSIGSKIRDQHQSTHSLDSKLYKDQFLTPDAWIDSLTLPQDCTMSPLVSRPN---------------------------SVANKPKSSPNLQDHSFVPSGSQSHVPQRRASKSPNGFTNDQHSQRNLMSERNAHTALPPGGSSLPRAYYPSLSTLPSERR------------------NQSHQAGREEEDMDGQDMDVEINIYRKGSETEGSYRSYGSQSSGRGSMDAP--NSRQFSLSPPLTSSPETTEDS--DRDEAALLDPEQNGRRDSVDESYEWEP-AYVPMRPVVSMNKTGLQKEFKGSQRKQSSITKDDDSSNLDQKQKGLYPAAGLKGSVP-----------------LFEVPCVPPSQCQQESLLTRDIQKSFTSFSDPEPDTVLF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q967D7-2", "uniprot_id": "TUTL_DROME", "id": "Q967D7-2", "name": "Protein turtle", "aln": "MGVCADLGSHRWCRALSTQHNTEKSKEQQQQSQPLEIPEQRASKCRGDIDRTTTTTIPASKTLTASPAKTAAFTVKTTRRRRSRRRAEGSSICVPIRRGQGSTPTPTIQVLQFVLVSLLALLAKNAQAHNIPEDAVHITAILGEGVIFNCHVEFPNDHP-----------VPYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDP--KQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATLMAVTQLVIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFREAGVN------DWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAPAAPRNVKAATQPPDSFFQLMPDEAGPKPGPPRNVSVTEVSNGFLITWQSPLERAHIVKFYTIKYRTDAQWKTLNRGQIRPEETQYLVKNLVGGRTYYFRVLANSEKSYE--SSDEVKFPVPARVK----------HKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQEKEFNMVACRITDARNIAANNHHLHNRSTGSISSGQVPLKKYK-------QTRISSLTAILIAILHWIWPPDRCTNCHSIYSSPNLEDGDEDDGGGGRRRSVSRIQRSLDGRFVLDVEGVSKLGYSQQTLESG-------------------------------------------------NVDVVDGGLFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------RRNSNVSQKSSSDDGGFLSRRNFITARASWRRPLVASSSQLSLQSAADSARGFLQGLLKIG--------------------------------------------------------------------------------------------AKQSAVPPNSQSYFDEAVSG-----------------------------------------------------------------------------------------------------------------------------------ARYQNVLRPYTSSNNLYGN--------------------------------------------------------------------------------------------ADRSRPLHINTISGSLSQQQQLYTPSRIS-----------------RIFSSSPQQLQPHHQQLLLSSGGSGAYP-----------------THFSDLSTVYPPNSAERSSHNLSSRYR-----------------------------------------------------------------------------YYSQELPSLRTIQEETRRQQQQKQHPLEDHFVPLQLPSPPSWRSYYQSQASYRPRTRWYPRHHSRLFSNRQQQHEMLS-------------------PLPQLNLNLRNSMNPGGLEASPESRSSSSGFGSKNTSNHPGSTSEWRLLPPYRAPPSPPKHSGYFGGQQAQGQTPHGSYSYPRATTPPYTMAHWLEMISRLNAATDSNLPKAPCPVDVGSVDGHYEFDPATPTPSASSMLREDLNLHIDTHPYHHHTLGPLSGSLLHSHAPYGGGARKQRSLPAHLPRYDNVEVRLQAMREEFYAYRKRQAMQQMESVC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U4G1-1", "uniprot_id": "BDL_DROME", "id": "Q9U4G1-1", "name": "Protein borderless", "aln": "------------------------------------MPAKRSRTFR-----------QSGSALLALLAIILLMNISCTSAARDHRRQTN------------------------------------------------LEAKVGSHVVFNCYIDFPFDAP-----------IPYLVHWTKDNKK------IFTWYEQETS-TSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNRSP--SVRNNGTAYHLAVQG--------------------------------------------------------------------------------------------GSLIRIPPVNQTIREGQTAFFHCVMKHPE-NSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLP---ADRFSLSGGNLTITGLVEGDRGIYECSATNEAATITAEAELMIENIAPRAPYNLTANSTETCITIRWQPGYLRPN---LEYTVWYRLMEAP------EWRTLRVLDKKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLPSPIRADD--FDAQQLQHDLGQVTAPAGG--LGAPWNLTAISNQQGWLLHWEHPVQGLEGLRLYAVRWWKEPEHFLIG--HAETFDNYYQLRHLKEDTLFKVQVLAVGTETQQSVPSHELLIDVPSQRK----------VRALIIGSSVGVIFLLCALCAFLYVKRSCLR------------------------------------------------------------------------------------HLFAKDSSASEDED------------------------------------TAESG-------------------------------------------------DCDSDEQDQRD-------------------------------------------------------------------------------------------------------------------------------------------------------------------RDSIKIRQST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . : * : * :::.* : * : **: :*: : : .*:**:.*:: :: *: * : . .:* :.* : . .: . : * : * * :: : .: * *. : **:* : .* * * * *. :*.* *.: : *:* * ** . : * .::.* : : * ** :: . :**:.:: ::: * * **.** ** * * *:: ** * *. * :.:* : *. * * : * : ....: : * . * ::* * .* : : : : . *:. .:: . .: * .*: :::* :* :: : * . *:* *:.:: * * :*: . . .* : . * *: * * : : :. : * . : .:::: . . . . . : * *: :: .: : . . * ", "identical_positions": 90, "similar_positions": 159, "identity": "4.09%" }, { "cls_id": "homologset.agr.MGI:2135548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI24-1", "uniprot_id": "IL24_RAT", "id": "Q9JI24-1", "name": "Interleukin-24", "aln": "-------------------------------------MQTSLRQQILPGLSLILLVLNQVPELQGQEFRFGPCQVTGVVLPELWEAFWTVKNTVKTQDELTSVRLLKPQVLQNVSDAESCYLAHSLLKFYLNTVFKNYHSKIVKFKVLKSFSTLANNFLVIMSKLQPSKDNAMLPISDSARRRFLLYHRTFKQLDIEVALAKAFGEVDILLAWMQNFYQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925S4-1", "uniprot_id": "IL24_MOUSE", "id": "Q925S4-1", "name": "Interleukin-24", "aln": "MLTEPAQLFVHKKNQPPSHSSLRLHFRTLAGALALSSTQMSWGLQILPCLSLILLLWNQVPGLEGQEFRFGSCQVTGVVLPELWEAFWTVKNTVQTQDDITSIRLLKPQVLRNVSGAESCYLAHSLLKFYLNTVFKNYHSKIAKFKVLRSFSTLANNFIVIMSQLQPSKDNSMLPISESAHQRFLLFRRAFKQLDTEVALVKAFGEVDILLTWMQKFYHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13007-1", "uniprot_id": "IL24_HUMAN", "id": "Q13007-1", "name": "Interleukin-24", "aln": "------------MNFQQRLQSLWTLARPFCP--PLLATASQMQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :** *.: **: .**. :****:**.***.*** :******:**:*:::**::** ***: :**:***.******.*:**:***:*******.: .:.:.*:*********::*:*:****::* *:.* :**::****::*:***** *.**.**:*******:***:**:*", "identical_positions": 108, "similar_positions": 55, "identity": "49.09%" }, { "cls_id": "homologset.agr.MGI:2135589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4KWA5-1", "uniprot_id": "CL2D2_RAT", "id": "A4KWA5-1", "name": "C-type lectin domain family 2 member D2", "aln": "MPSSAHLQDAPPLLSRTLTQDEEQTSLRQSSSCG--LSAASASESLSGSTKSRIPHSKMLQGNLPRIISPESPAKLPCCYG-VIMVLSVAVVA-LSVALSVKKT--PQILT----------------VKTYAACPRNWIGVGNKCYYFNETPSNWTFSQTLCKAQEAELARFDTEEELNFLKRHKGSSGYWIGLHRESSSQPWKWTDNTAYNNLVPIGGDEKHGFLSDNG-FSSGRGYIVRKSICSKPNSYTSQCQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5M9I1-1", "uniprot_id": "CL2DR_RAT", "id": "Q5M9I1-1", "name": "C-type lectin domain family 2 member D-related protein", "aln": "MPSSAHLQDPPPHLSRTLTQDEEQTSLRQSSSCGPSTTSASASESLSGSTKSRISQKKLLEGMLPKIIPTESAAKLLCCYA-VFMALTVVVIA-LSIALSVKKT--PQISA----------------VNTYAACQRNWIGFGNKCYYFNETARNWTFSQTLCKEQEAELARFDNEEELNFLKRYKGSSGYWIGLHRESSADPWKWTDNTAYNNLVPIKGEEKHGFLSDNG-LSSGKDYIKRKSICSKLNSYTSQCP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925N7-1", "uniprot_id": "CL2D5_RAT", "id": "Q925N7-1", "name": "C-type lectin domain family 2 member D5", "aln": "MPSSAHLQDPPPLLSRTLTQNEGQTSLRQSSSCG--PSAASASESLSGSTESRIPHSKMLQGKLPRNIPLEYPAGLYCCYV-VIIVLSVAVVA-LSVALSVKKT--AQIST----------------INTYAACPRNWIGVGNKCFYFNEIPSNWTLSQTLCKEQGAELARFDTEEELNFLRRYKGSSGYWFGLHRESSAHPWKWTDNTEYNNSVSIGGDEKHGFLSDNG-FSSGRGYIVRKSICRKPNSYTSQCL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4KWA6-1", "uniprot_id": "CL2D3_RAT", "id": "A4KWA6-1", "name": "C-type lectin domain family 2 member D3", "aln": "MSSSAHLQDAPPLLSGTLTQNEGQTSLRQSSSCG--PSAASASESLSGYTESRIPHSKVRQGKGLRSIFPESRVKRYCCYGGVITVVAIAIVVPLSVTLSVKQM--EQTSINNTSAASINNTSAASINNTSAACPSNWTEYGNKCFYFSEYTSNWTFSKDFCAAQGAELARFDTEEELNFLKRYKGSSGYWIGLHRESSEHPWKWTDNTQYNNLIPIRGDGQCGFLSDQLNISSSRVYVERPWICSKPKKYISQSQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0H8B9-1", "uniprot_id": "CL2DB_RAT", "id": "Q0H8B9-1", "name": "C-type lectin domain family 2 member D11", "aln": "---MSAKKASQPMLNTTGSLQEGE--------MG-----------------------KMFHGKCLRIVSPESPAKLYCCYG-VIMVLSVAVVA-LSVALSVKMT--PQIST----------------INTYAACPRNWIGVGNKCFYFSEYASNWTFSQTFCKAQEAELARFDTEEELNFLSRYKGSFDYWIGLHRESSEHPWKWTDNTQYNYSLSIRGVERYAYLNDIG-ISSARVYADKRWSCSKLNSYSLQCKTPFSPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V08-1", "uniprot_id": "CLC2D_MOUSE", "id": "Q91V08-1", "name": "C-type lectin domain family 2 member D", "aln": "---MCVTKASLPMLSPTGSPQEVE--------VG-----------------------KILQGKRHGTISPESCAKLYCYYG-VIMVLTVAVIA-LSVALSATKT--EQIPV----------------NKTYAACPQNWIGVENKCFYFSEYPSNWTFAQAFCMAQEAQLARFDNQDELNFLMRYKANFDSWIGLHRESSEHPWKWTDNTEYNNTIPIRGEERFAYLNNNG-ISSTRIYSLRMWICSKLNSYSLHCQTPFFPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHP7-1", "uniprot_id": "CLC2D_HUMAN", "id": "Q9UHP7-1", "name": "C-type lectin domain family 2 member D", "aln": "------MHDSN-NVEKDITPSELP-----------------------------------ANPGCLHSKEHSIKATLIWRLFFLIMFLTIIVCG-MVAALSAIRANCHQEPS----------------VCLQAACPESWIGFQRKCFYFSDDTKNWTSSQRFCDSQDADLAQVESFQELNFLLRYKGPSDHWIGLSREQG-QPWKWINGTEWTRQFPILGAGECAYLNDKG-ASSARHYTERKWICSKSDIHV----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :. : .* . . . :: ::: : : :**. * *** .* .**:**.: . *** :: :* * *:**:.:. :***** *:*. . *:** **.. .**** :.* :. ..* * . .:*.: ** : * : * * . : ", "identical_positions": 45, "similar_positions": 55, "identity": "17.18%" }, { "cls_id": "homologset.agr.MGI:2135593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64428-1", "uniprot_id": "ECHA_RAT", "id": "Q64428-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MVASRAIGSLSRFSAFRILR---------SRGCICHS--FTTSSALLSRTHINYGVKGDVAVIRINSPNSKVNTLNKEVQSEFVEVMNEIWANDQIRSAVLISSKPGCFVAGADINMLASCTTPQEAARISQEGQKMFEKLEKSPKPVVAAISGSCLGGGLELAIACQYRIATKDRKTVLGVPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVDPLGPGIKSPEERTIEYLEEVAVNFAKGLADRKVSAKQSK-GLMEKLTSYAMTIPFVRQQVYKTVEEKVKKQTKGLYPAPLKIIDAVKTGLEQGNDAGYLAESEKFGELALTKESKALMGLYNGQVLCKKNKFGAPQKTVQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQLDYKGFEKADMVIEAVFEDLAVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSQRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDALTTGFGFPVGAATLADEVGIDVAQHVAEDLGKAFGERFGGGSVELLKLMVSKGFLGRKSGKGFYIYQSGSK-NKNLNSEIDNILVNLRLPAKPEVSSDEDIQYRVITRFVNEAVLCLQEGILATPEEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKVVDRLRKYESAYGTQFTPCQLLRDLANNSSKKFYQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMS1-1", "uniprot_id": "ECHA_MOUSE", "id": "Q8BMS1-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MVASRAIGSLSRFSAFRILR---------SRGCICRS--FTTSSALLTRTHINYGVKGDVAVIRINSPNSKVNTLNKEVQSEFIEVMNEIWANDQIRSAVLISSKPGCFVAGADINMLSSCTTPQEATRISQEGQRMFEKLEKSPKPVVAAISGSCLGGGLELAIACQYRIATKDRKTVLGVPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVEPLGPGIKSPEERTIEYLEEVAVNFAKGLADRKVSAKQSK-GLVEKLTTYAMTVPFVRQQVYKTVEEKVKKQTKGLYPAPLKIIDAVKAGLEQGSDAGYLAESQKFGELALTKESKALMGLYNGQVLCKKNKFGAPQKNVQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQLDYKGFEKADMVIEAVFEDLGVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLRQGKVIIVVKDGPGFYTTRCLAPMMSEVMRILQEGVDPKKLDALTTGFGFPVGAATLADEVGVDVAQHVAEDLGKAFGERFGGGSVELLKQMVSKGFLGRKSGKGFYIYQEGSK-NKSLNSEMDNILANLRLPAKPEVSSDEDVQYRVITRFVNEAVLCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKVVDRLRKYESAYGTQFTPCQLLLDHANNSSKKFYQ-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40939-1", "uniprot_id": "ECHA_HUMAN", "id": "P40939-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MVACRAIGILSRFSAFRILR---------SRGYICRN--FTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDK-GLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVK-RKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V397-1", "uniprot_id": "Q9V397_DROME", "id": "Q9V397-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MSATRFLSAVGQISRQQLLQNKCTRALPISAQLLQRRRLMSTNPAPVANKHLHTKVVNGVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADIGMLEACQTAEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEVMLGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYLEKTAVQVANDLASGKLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGLYPAPLKILDVIRAGVDKGTDAGYEAERKGFGELSATPESKGLIALFRGQTECKKNRFGKPERPVKTVGVLGAGLMGAGIVQVSVDKGYQVVMKDATEAGLARGIGQVQKGLETAVKRKRISALERDQTLASLRPTLDYSDFKNADIIIEAVFEDIKVKHRVIKELEAVVPEHCVIATNTSAIPITKIAAGSSRPEKVVGMHYFSPVDKMQLLEIITHPGTSKDTIAQAVAVGLKQGKVVITVGDGPGFYTTRILSTMLSEAIRLLQEGVDPKDLDQYTKKFGFPVGAATLADEVGIDVGSHIAVDLAKAFGERFSGGNLEVMNDLVLAGFLGRKSGKGIFLYDGQKRGTRPVNNDALEIVKQKYALVSKGANAPEDLTLRMVSRFINEAVLCLEEKILDSPLEGDVGAVFGLGFPPFSGGPFRWVDQYGAGKLVSKMQSYAELYGAPFKPAQTLLDMAKDPSKKFYPKTGSSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * :. :.::* ::*: * : : :: ..* ::..*:: * ..* *::*:***:***:*..*: .** .*:::: :. :.******.*****:*****.** :* * :*.: :*: .* :.:::*:* **:****.* *******:*::*:******* ** ** ***:** ***.*** ****:..**:*:** ***:.:******::*:** **:*****::..*:.******:.*: .*:.**. *: ::.* **:.*: ::.* **:::::....::* * ::*********:*.:::*:::*.**** .* : **** * ***.*:.*:.**. ****:** *:: *: :.:**********.******* :.::**:* :.* ** ** ***: **:* ::::***. ::.* ***..*::**::*******: :**:*:**:*:* *:**::*:****:**.:*** *.*****:****************** ***** *.******:****:*.* ********* *:.*:**.:*:********.** *. **********.****:**..*:* **.*.*****.**. *::. :* **********:::*: : : :*.: .*: . . ..: **: *:::**:****:**:* ** :* ***:********** *****:** *** *:*.:::.* ** *.*.* * * *:...**** ", "identical_positions": 403, "similar_positions": 239, "identity": "51.47%" }, { "cls_id": "homologset.agr.MGI:2135601", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43007-1", "uniprot_id": "SATT_HUMAN", "id": "P43007-1", "name": "Neutral amino acid transporter A", "aln": "-MEKSNETNGYLDSAQAGPAAGPGAPGTAAGRARRCAGFLRRQALVLLTVSGVLAGAGLGAALRGLS--LSRTQVTYLAFPGEMLLRMLRMIILPLVVCSLVSGAASLDASCLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGSGAQTLQSSDLGLEDSGPPPVPKETVDSFLDLARNLFPSNLVVAAFRTYATDYKVVTQ-NSSSGNVTHEKIPIGTEIEGMNILGLVLFALVLGVALKKLGSEGEDLIRFFNSLNEATMVLVSWIMWYVPVGIMFLVGSKIVEMKDIIVLVTSLGKYIFASILGHVIHGGIVLPLIYFVFTRKNPFRFLLGLLAPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVELNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLPLILAVDWIVDRTTTVVNVEGDALGAGILHHLNQKATKKG----------------EQELAEVKVEAIPNCKSEE--ETSPLVTHQNPAG--PVASAPELESKESVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35874-1", "uniprot_id": "SATT_MOUSE", "id": "O35874-1", "name": "Neutral amino acid transporter A", "aln": "-MEKSGETNGYLDGTQAEPAAGPRTPETAMGKSQRCASFFRRHALVLLTVSGVLVGAGMGAALRGLQ--LTRTQITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASLDASSLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGAGAQTLQSSSLGLENSGPPPVSKETVDSFLDLLRNLFPSNLVVAAFTTSATDYTVVTH-NTSSGNVTKEKIPVVTDVEGMNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVEMKDIVMLVTSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILAVDWIVDRTTTVVNVEGDALGAGILNHLNQKVVKKG----------------EQELQEVKVEAIPNSKSEE--ETSPLVTHQNPAG--PVAIAPELESKESVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5C4-1", "uniprot_id": "A0ACD6B5C4_DANRE", "id": "A0ACD6B5C4-1", "name": "Amino acid transporter", "aln": "MEEKKSEINGHAGHKCSLPTVSIKSEKKSCKDT--CAGFFKRNLLVIMTVSGVLVGVGLGMMVRNMN--LTRAQMTYFAFPGEMLLRMLKMIILPLVVCSLISGAASLDTRSLGKLGGIAVSYFLVTTLIASSIGVALAFIIKPGVGAGALNTNNLGLEGVSN---NKETADSFLDLARNLFPSNLVAAAFRSYATDYKTVLIGNGTNGTLNYQKVPFGTDTDGMNILGLVLFAMVFGVALRKLGAEGEELIRFFNAFNEATMVLVSWIMWYVPFGIMFLVGSKIVEMEDVVLLVTSLGKYIFASILGHIIHGCIILPLIYFGFTRTNPYSFLSGLITPFTTAFATCSSSATLPTMMKCVEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVHLNAGQIFTILVTATASSVGAAGIPAGGIITIAIILEAIGLPTHDLSLMLAVDWIVDRTTTVVNVEGDALGAGILHHINEQEMKKQKHQ--------QEHQEEQELLEVKVEVVANVKAEE--ETSPLVTHQNQEENSSRETLNDKDGVESVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6H2EJK0-1", "uniprot_id": "A0A6H2EJK0_DROME", "id": "A0A6H2EJK0-1", "name": "Amino acid transporter", "aln": "-------------------------MTRPKQDGGKFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASK----VLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYENTSISPAQPMENWEFK--SAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLD-NMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLNAEPHELLELGPNGHEMKEXRQSSLGAYNRKRXVDMSRLWACFHILPSNDSDSDDYDDDDEEF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*::.: *.: ** **:.* :* ::. :: :: *::****::****: :*:**:*.*: *. ..** .::. *::*: :**: * :.:.*. ::** ** :::. .:: . * *:::** **:*..*:: ::: *: . :. . : :: :* *:****:*::::*.:: :: :*: * **.::.** *.:.**::* *.*: **:.:**:**:.: : *** *::: ::* .:** :.:::* ** *: :: * ::***.* *****:* :**:: * *:* *::**::*:***:****:*:::.***:**** .:: . * *.:: :****:*:****:* .*::*:.::*:::** .:*:.*::****::** *.:** ****: :::*:.:: . :*: * : . : : :. : * * : : :. *.. ", "identical_positions": 154, "similar_positions": 197, "identity": "27.7%" }, { "cls_id": "homologset.agr.MGI:2135604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QUZ8-1", "uniprot_id": "GMEB1_RAT", "id": "Q9QUZ8-1", "name": "Glucocorticoid modulatory element-binding protein 1", "aln": "MANAEVSVPVGDVVVVPTEGNEGENPED-TKTQVILQLQPVQQG----------IYEAGSENSAAVVAVETHTIHKIEEGIDASSIEANEDMEIAYPITCGESKAVLLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIHAPFQVTDAAVLNNVANTFGLMDTVKRVLDNRRKQVEHGEEQFLYTLADLERQLEEQKKQA-QDPRLKSQTVQNVVLMPVSTPK-PPKRPRLQRPASTTVLS---PSP-VQQPQ-FTVISPITITPVGQSFSMGNIPVATLSQGTSPVTVHTLPSGPQLFRYATVVSSAKSNSPDTVTIHPSSSLALLSSTSMQDGSTLGNMATMVSPVELVAMESGLTSA-------------------IQAVES-TSEDGQTIIEIDPAPDP----------EADDPEGKAVILETELRTEEKVVANMEER-------QHQVHNVEIVVLED---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL60-1", "uniprot_id": "GMEB1_MOUSE", "id": "Q9JL60-1", "name": "Glucocorticoid modulatory element-binding protein 1", "aln": "MANAEVSVPVGDVVVVPTEGNEGENPED-TKTQVILQLQPVQQG----------IYEAGSENSAAVVAVETHSIHKIEEGIDASSIEGNEDMEIAYPITCGESKAVLLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEMEELLRGVQQRLIQAPFQVTDAAVLNNVANTFGLMDAVKRVLDNRRKQVEQGEEQFLYTLADLERQLEEQKKQA-QDPRLKSQTVQNVVLMPVSTPK-PPKRPRLQRPASTTVLS---PSP-VQQPQ-FTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSNSPDTVTIHPSSSLALLSSTSMQDGSSLGNMATMVSPMELVAMESGLTSA-------------------IQAVES-TSEDGQTIIEIDPAPDS----------EADDTEGKAVILETGLRTEEKVVAEMEEH-------QHQVHNVEIVVLED---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y692-1", "uniprot_id": "GMEB1_HUMAN", "id": "Q9Y692-1", "name": "Glucocorticoid modulatory element-binding protein 1", "aln": "MANAEVSVPVGDVVVVPTEGNEGENPED-TKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQG-QDHRLKSQTVQNVVLMPVSTPK-PPKRPRLQRPASTTVLS---PSPPVQQPQ-FTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSA-------------------IQAVES-TSEDGQTIIEIDPAPDP----------EAEDTEGKAVILETELRTEEKVVAEMEEH-------QHQVHNVEIVVLED---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNH6-1", "uniprot_id": "A0A8M9PNH6_DANRE", "id": "A0A8M9PNH6-1", "name": "", "aln": "MAEAEVTVTVEDMVVMKSSEEEDVEPDNQSKTQMILQLQPMTAG----------LGDESNETDAAVVAVE-----------DEVSAEG-EDLELGYPITCGESKAILLFKKFVCPGINVRCVKYEDQLISPKQFVHMSGKATLKDWKRAIRMGGVMLRKMMDSGQLDFYQHSTLCTNTCRSTKFDLLINNTRFPPDGSGLNTPITAAEYVFPAGHVTVGNGGQAATVEEKKEDVIGAVEWSPDTSDKRDTSEISEETLSFWRGIAEVGLMGEVVSNIRSELLGLLRGVQLRTDQSSLQDAEIAVLSNLAQVFNLLDSIKQILNVRRQMTDPEQTQVLRTLTTLEQQLEEQKMQQSLSWSSQSQALSSLVLPSTPPAKRAPKRPRLQRPASTTVLSTSIAQPLTLQPQQFTVFSPITLSSIGQSF-----AVANLSPPSNTVTLHALPAGSQLF---TRIAGGSDGKTEAITLHPASGLTLLGATAMQDPSQLG---TVVSPVELVQLTQKATNAGVTQDGQVVTGTVVMQEGVVRVVQEDENQENATLIEIDPATADQSVSVMELQLEGDEAAGAATVVE---GGEEVVQGEMEETGEIQLDANGQFHNLPIVVVEEDEQDVGKAK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:***:*.* *:**: :. :*. :*:: :***:******: * : : ..*..:****** * : *. **:*:.**********:**:**********:***::*******:***::**:**********:**:**********:*****..:*:************..:* * *. .. *.:. ::::.: . : * :. : .** :.: . *:::.****:** **:***:**** ***.**:.*: ****** * ::.:* :: ***.*:*:.*.*:*::*::*: **: .: : *.* **: **:****** * . :**::..:** .....* .**************** ..* . *** ***:****::.:**** .**.** :..**:*:**:*.*** * ::.......:::*:**:*.*:**.:*:*** * ** *:***:*** : . *.* ::.*:. .::. *:******. *.::. * *.::* ** * .:*** : *.**: ***:*: ", "identical_positions": 271, "similar_positions": 182, "identity": "43.29%" }, { "cls_id": "homologset.agr.MGI:2135605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2F2-1", "uniprot_id": "D4A2F2_RAT", "id": "D4A2F2-1", "name": "", "aln": "MNRGHRHGVSSGCLG---TMEVKSKFGAEFRRFSLERSKPGK-FEEFYGLLQHVHKIPNVDVLVGYADIHG-DLLPINNDDNYHKAVSTANPLLRVFIQKKEEA-DYSAFGTDTLIRKKNVLSNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQAGASLEPEDQDSDEDDIIIEGSGEPQQIPKATPEALSLESLTQIELSFESGQNGFSPLQDTSLVAVPSSLDTESESRAPDQKLLEEDGTIITL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK83-1", "uniprot_id": "PAR6B_MOUSE", "id": "Q9JK83-1", "name": "Partitioning defective 6 homolog beta", "aln": "MNRGHRHGASSGCLG---TMEVKSKFGAEFRRFSLERSKPGK-FEEFYGLLQHVHKIPNVDVLVGYADIHG-DLLPINNDDNYHKAVSTANPLLRIFIQKKEEA-DYSAFGTDTLIRKKNMLSNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSSQSTDNSLLGFPQQVEASFEPEDQDSDEDDIIIEDSGEPQQIPKATP-AQSLESLTQIELSFESGQNGFSPPQDTSLVPVPGSLDTELESRAPDQKLLEEDGTIITL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYG5-1", "uniprot_id": "PAR6B_HUMAN", "id": "Q9BYG5-1", "name": "Partitioning defective 6 homolog beta", "aln": "MNRSHRHGAGSGCLG---TMEVKSKFGAEFRRFSLERSKPGK-FEEFYGLLQHVHKIPNVDVLVGYADIHG-DLLPINNDDNYHKAVSTANPLLRIFIQKKEEA-DYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97111-1", "uniprot_id": "O97111_DROME", "id": "O97111-1", "name": "", "aln": "MSKNKINTTSATAASDTNLIEVKSKFDAEFRRWSFKRNEAEQSFDKFASLIEQLHKLTNIQFLILYIDPRDNDLLPINNDDNFGRALKTARPLLRVIVQRKDDLNEYSGFGT---MKPRNLIGSILMGHTPVKTKAPSISIPHDFRQVSAIIDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVTDMMVANSSNLIITVKPANQR---TLTSTHRGS--FSRNSQLSSGSHHTNNTNTSDEIEHDDQDDIVDLTG---------------VTLDESPTSTSAGNHNHQPP----LSSSPSSHHQQAASNASTIMASDVKDGVLHL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:.: : ..: . . :******.*****:*::*.:. : *::* .*::::**:.*::.*: * * :. **********: :*:.**.****:::*:*:: :**.*** :: :*:: .:* .. *. **:*:*** **:******:********* *:*::**********:*****. **** **************:***********:*******:**:********:*** ******:***** . .* ** * :..* . .:: : .:: : :::* *:: .* :* : * .:*::.. * * . ..* . : :.*. : .. :: *", "identical_positions": 166, "similar_positions": 113, "identity": "43.92%" }, { "cls_id": "homologset.agr.MGI:2135606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M1M4-1", "uniprot_id": "A0ABK0M1M4_RAT", "id": "A0ABK0M1M4-1", "name": "", "aln": "MNRS-FHKSQTLRFYDCSAVEVKSKPSRGDLQAVGWGLLEANTSSGSSSMGNQFGAEFRRFSLDRHKPGK-FEDFYQLVVHTHHISNTEVTIGYADVHG-DLLPINNDDNFCKAVSSANPLLRVFIQKREEADHYSFGAGTLSRKKKVLVTLRDEGLRRRAQLNISMPHDFRPVSSIIDVDILPETHRRVRLYRHGCEKPLGFYIRDGTSVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRSSRASGSSVQSTDSTTSHHSLPGTHALQ--NSEEMESDEEADIVIEGALEPHHIPKMQAVPPGSLSRANGASLAHRLHRGDVGLHSSGRESNGSIHRFLSSLKPDPRHSLVLPQGGVEEHGPAITL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK84-1", "uniprot_id": "PAR6G_MOUSE", "id": "Q9JK84-1", "name": "Partitioning defective 6 homolog gamma", "aln": "MNRS-FHKSQTLRFYDCSAVEVKSK----------------------------FGAEFRRFSLDRHKPGK-FEDFYQLVVHTHHISNTEVTIGYADVHG-DLLPINNDDNFCKAVSSANPLLRVFIQKREEADHYSFGAGTLSRKKKVLVTLRDDGLRRRPHLNISMPHDFRPVSSIIDVDILPETHRRVRLYRHGYEKPLGFYIRDGTSVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRSSRTSGSSVHSTDSTTSHHSLPGAHVLQ--NSEDVESDEEADIVIEGALEPQHIPKTQAVPPGSLSRANGTSLAHGLHRRDMSLHSSGRESNGSIHRFLSSLKPDPRHSLVLPQGGVEEHGPAITL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYG4-1", "uniprot_id": "PAR6G_HUMAN", "id": "Q9BYG4-1", "name": "Partitioning defective 6 homolog gamma", "aln": "MNRS-FHKSQTLRFYDCSAVEVKSK----------------------------FGAEFRRFSLDRHKPGK-FEDFYKLVVHTHHISNSDVTIGYADVHG-DLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRALGALRDEGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDNDVVIEGTLEPARPPQTPGAPAGSLSRVNGAGLAQRLQR-DLALD-------GGLQRLLSSLRADPRHSLALPPGGVEEHGPAVTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97111-1", "uniprot_id": "O97111_DROME", "id": "O97111-1", "name": "", "aln": "MSKNKINTTSATAASDTNLIEVKSK----------------------------FDAEFRRWSFKRNEAEQSFDKFASLIEQLHKLTNIQFLILYIDPRDNDLLPINNDDNFGRALKTARPLLRVIVQRKDDLNEYS-GFGTMKPRNLIGSILMGHTPVKTKAPSISIPHDFRQVSAIIDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVTDMMVANSSNLIITVKPANQR--TLTSTHRGSFSRNSQLSSGSHHTNNTN------TSDEIEHDDQDDIVDLTGVTLDESP--TSTSAGNHNHQPPLSSSPSSHHQQAASN--------ASTIMASDVKDGVLHL-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:. ::.:.: * . :***** *.*****:*:.*::. : *:.* .*: : *:::* :. * * * :. *********** :*:.:*.*****::*:::: :. * * *:: :. * .. : .*.:*:*** **:*****::********* :** :**********:*****. **** *******:******************:*******************:*** ***:******** .: . : . * . .: .. .:: * *:: *:* : . * ....*. .: . : :: : . . . : *.:: . * ", "identical_positions": 155, "similar_positions": 104, "identity": "37.35%" }, { "cls_id": "homologset.agr.MGI:2135607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ79-1", "uniprot_id": "SIR1_RAT", "id": "A0A0G2JZ79-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEAALALQAGGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEPSAAAAAAAAAAGCEAASAAAPAALWREAAGAAAASA-EREAPATAAAGDGDNGPGLR---REPRAADDFDDDEGEEEDE-AAAAAAAAIGYRDNLLLADEIITNGFHS--CESDDDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRK--------KRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQ--RIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQKELVHLSELPPTPLHISEDSSSP---------ERTVPQDSSVIATLVD-----------------------------QTIKNKVDDLEVSEPKSCVEEKSQEVQTYRN-------VESIN--VENPDFKAVGSSTGDK--------------------NERTSVAETV----------------------RKCWPNRLAKEQISKRLDGNQYLFVPPNRYIFHGAEVYSD--SEDDALSSSSCGSNSDSGTCQSPSLEEPLEDESEIEEFYNGLEDDADRPECAGGS--GADGGDQEAVNEAIAMKQELTDVNCTPDKSEHY-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923E4-1", "uniprot_id": "SIR1_MOUSE", "id": "Q923E4-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEVALALQAAGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEP--SAAVAPAAAGCEAASAAAPAALWREAAG-AAASA-EREAPATAVAGDGDNGSGLR---REPRAADDFDDDEGEEEDEAAAAAAAAAIGYRDNLLLTDGLLTNGFHS--CESDDDDRTSHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRK--------KRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQ--RILQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRPQKELVHLSELPPTPLHISEDSSSP---------ERTVPQDSSVIATLVD-----------------------------QATNNNVNDLEVSES-SCVEEKPQEVQTSRN-------VENIN--VENPDFKAVGSSTADK--------------------NERTSVAETV----------------------RKCWPNRLAKEQISKRLEGNQYLFVPPNRYIFHGAEVYSD--SEDDVLSSSSCGSNSDSGTCQSPSLEEPLEDESEIEEFYNGLEDDTERPECAGGSGFGADGGDQEVVNEAIATRQELTDVNYPSDKS--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EB6-1", "uniprot_id": "SIR1_HUMAN", "id": "Q96EB6-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHS--CESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRK--------KRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQ--RIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSP---------ERTSPPDSSVIVTLLD-----------------------------QAAKSN-DDLDVSESKGCMEEKPQEVQTSRN-------VESIAEQMENPDLKNVGSSTGEK--------------------NERTSVAGTV----------------------RKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGAEVYSD--SEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA52K8U1-1", "uniprot_id": "A0AA52K8U1_DANRE", "id": "A0AA52K8U1-1", "name": "protein acetyllysine N-acetyltransferase", "aln": "-MADG---------------ENKRAESAEPDEPLPKKPR-------------------------------------LLELSG-------DSEHSATAGADTLDEKPARMD---ESQQALSINNNNNTRPTEPGQPADPEPE---ISELTDEGVHSNGFTSPDLLRDDDDCSSRASSSDWTPQPQIGSYRFIQQHIMRGTDPRAILKDLLPETVL--PPDLDDMTLWQIIINIS-EPPKRK--------KRKDINTLEDVVRLLNERKKILVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIDYFRRDPRPFFKFAKEIYPGQFQPSPCHRFISMLDKKGRLLRNYTQNIDTLEQVAGIQ--KIIQCHGSFATASCLICKHKVDCEAIREDIFNQVVPHCPRCPSDVP------------------------------YAIMKPDIVFFGENLPEFFHRAMKQDKDEVDLLIVIGSSLKVRPVALIPSSIPHDVPQVLINREPLPHLNFDVELLGDCDVIVNELCHRLNG---DFQQLCYNSSRLSEITEKPAAPEHTENTSADHSHADAEHIENTSADRDDADAEHIENTSADHSHADAEHIENTSADRDDADAEHIENTSADHSHADAEHIENTSADRDDAEHTENTPTDHANAEHTEHTSAGHVNAEHIEHMSTDHANAKDDQSSLSVNEEELASPAAETHALDSTEISAHTERSKEADAVNTDDAACVKDEENTDRLRVEMRRRCWRSRICQSPISKRLGASQYLFQAPNRYVFHGAEVYSS--SEDE--SSSSCSSESD-GSFQH--------EDSEVEENGAAMTDKET---------------DTETVQDSEHRRLQTHCTQHTQ-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK34-1", "uniprot_id": "SIRT1_DROME", "id": "Q9VK34-1", "name": "NAD-dependent histone deacetylase sirtuin-1", "aln": "MMENYEEIRLG-------HIRSKDLGNQVPDTTQFYPPTKFDFG-----------------------AEILASTSTEAEAEAEATATTTEPATSELAGKANGEIKTKTLAAREEQEIGANLEHKTKNPTKSMGEDEDDEEEEEEDDEEEEEDDEE-GITG---TSNEDEDSSSNCSSSVEPDWKLR---WLQREFYTGRVPRQVIASIMPHFATGLAGDTDDSVLWDYLAHLLNEPKRRN--------KLASVNTFDDVISLVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIYARLAHDFPDLPDPQAMFDINYFKRDPRPFYKFAREIYPGEFQPSPCHRFIKMLETKGKLLRNYTQNIDTLERVAGIQ--RVIECHGSFSTASCTKCRFKCNADALRADIFAQRIPVCPQCQPNKEQSVDAS-----------VAVTEEELRQLVENGIMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGSSLKVRPVAHIPSSIPATVPQILINREQLHHLKFDVELLGDSDVIINQICHRLSDNDDCWRQLCCDESVLTESKELMPPEHSNHHLHHHLLHHRHCSSESERQSQ----LDTDTQSIKSNSSADYILGSAGTCSDSGFESSTFSCGKRSTAAEAAAIERIKTDILVELNETTALSCDRLGLEGPQTTVESYRHLSIDSSKDSGIEQCDNEATPSYVRPS-----------------NLVQETKTVAPSLT---------------------PIPQQRGKRQTAAERLQPGTFYSHTNNYSYVFPGAQVFWDNDYSDDDDEEEERSHNRHSDLFGNVGHNYKDDDEDACDLNAVPLSPLLPPSLEAHIVTDIVNGSNEPLPNSSPGQKRTACIIEQQPTPAIETEIPPLKKRRPSEENKQQTQIERSEESPPPGQLAAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06700-1", "uniprot_id": "SIR2_YEAST", "id": "P06700-1", "name": "NAD-dependent histone deacetylase SIR2", "aln": "--MTIPHMKYAVSKTSENKVSNTVSPTQDKDAIRKQPDDIINND------EPSHKKIKVAQPDSLRETNTTDPLGHTKAALGEVASMELKPTNDMDPLAVSAASVVSMSNDVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDLNSLYIYYLIKLLGFEVKDQALIGTINSIVHINSQERVQDLGSAISVTN----VEDPLAKKQTVRLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGIPDFRSSEGFYS--KIKHLGLDDPQDVFNYNIFMHDPSVFYNIANMVLPPEKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTCHWNLPGERIFNKIRNLELPLCPYCYKKRREYFPEGYNNKVGVAASQGSMSERPPYILNSYGVLKPDITFFGEALPNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCGWT--------IPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53685-1", "uniprot_id": "HST1_YEAST", "id": "P53685-1", "name": "NAD-dependent protein deacetylase HST1", "aln": "--MNILLMQRIVS--------FILVVSQGR---------YFHVG------ELTMTMLKRPQEE---ESDNN-------------ATKKLKTR-------------------------LTYPCILGKDKVTGKFIFPAITKDDVMNARLFLKDNDLKTFLEYFLPVEVNSIYIYFMIKLLGFDVKDKELFMALNSNITSNKERSSAELSSIHAKAEDEDELTDPLEKKHAVKLIKDLQKAINKVLSTRLRLPNFNTIDHFTATLRNAKKILVLTGAGVSTSLGIPDFRSSEGFYS--KIRHLGLEDPQDVFNLDIFLQDPSVFYNIAHMVLPPENMYSPLHSFIKMLQDKGKLLRNYTQNIDNLESYAGIDPDKLVQCHGSFATASCVTCHWQIPGEKIFENIRNLELPLCPYCYQKRKQYFPMSNGNNT----VQTNINFNSP-ILKSYGVLKPDMTFFGEALPSRFHKTIRKDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQILINRDMVTHAEFDLNLLGFCDDVASLVAKKCHWD--------IPHKKWQDLKKIDYNCTEIDKGTYKIKKQPRKKQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : :. . : . . * . .: : : : .. *::. :. :**:********.* ******* :*:*: . .* *** :*: : * :** *:::*. : * : * * ** : : :*:**********.** ***. ::::*****:**:* *: : : : .* :* ** * . .::**::.**** **. :* : * **** **:**** **: * . :* ***:****: : * .**:.*** .* : :.:: : .: ", "identical_positions": 105, "similar_positions": 89, "identity": "11.38%" }, { "cls_id": "homologset.agr.MGI:2135608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z340-1", "uniprot_id": "PARD3_RAT", "id": "Q9Z340-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDP-----HHGGDGTS-ASSTGTQSPEIFGSELGTNN-VSAFRPYQTTSEIEVTPS--VLRANMPLHVRRSSDPALTGLS-TSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTTGSPKTCDRKKD--ENYRSLPRDPSSWSN--QFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREMNNYS----PGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPTAPALAPPNVLSTSVGSVYNTKRVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQE-------------------------------------------------EAFHPREMNAEPSQMQSPKETKAEDEDIVLTPD--GTREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMS-TEGNKRGMIQLIVARRISRCNELR--------------------------------SPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALS-RIMGESGKCQLSPTVNMPH----------------------------------------------------DDTVMIEDDRLPVLP-----PHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSL-----------SPDVDPVLAFQREGFGRQSMSEKRTKQFSNASQLDFVKTR-----KSKSMDLGIADETKLNTVDDQRAGSPNRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRP-RIIRGRGCNESFRAAIDKSYDKPMVDDDDE-GMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKAEKKKDKAGKDKKKDREKEKDKLKAKKG-MLKGLGDMFRFGKHRKDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQARERDYAEIQDFHR---TFGCDDELLYGGMSSYDG--CLALNARPQSPREGHLMDTLYAQVKKPRSSKPG--DSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQSWSSSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSVSQDSWEQNYAPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQLKKQPPADG-----------------VRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NH2-1", "uniprot_id": "PARD3_MOUSE", "id": "Q99NH2-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDP-----HHGGDGTS-ASFTGTQSPEIFGSELGTNN-VSAFQPYQATSEIEVTPS--VLRANMPLHVRRSSDPALTGLS-TSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD--ENYRSLPRDPSSWSN--QFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREKNNYS----PGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPAAPALAPPSVLSTNVGSVYNTKKVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQE-------------------------------------------------EAFHPREMNAEPSQMQTPKETKAEDEDVVLTPD--GTREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMS-TEGNKRGMIQLIVARRISRCNELR--------------------------------SPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALS-RIMG---KCQLSPTVNMPH----------------------------------------------------DDTVMIEDDRLPVLP-----PHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSL-----------SPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTR-----KSKSMDL-VADETKLNTVDDQRAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRP-RIIRGRGCNESFRAAIDKSYDKPMVDDDDE-GMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKTERKKDKAGKDKKKDREKEKDKLKAKKG-MLKGLGDMFRFGKHRKDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQARERDYAEIQDFHR---TFGCDDELLYGGMSSYEG--CLALNARPQSPREGHLMDTLYAQVKKPRSSKPG--DSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQSWSSSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSISQDSWEQNYAPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQLKKQPPADG-----------------VRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEW0-1", "uniprot_id": "PARD3_HUMAN", "id": "Q8TEW0-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDP-----HHGGDGTS-ASSTGTQSPEIFGSELGTNN-VSAFQPYQATSEIEVTPS--VLRANMPLHVRRSSDPALIGLS-TSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD--ENYRSLPRDTSNWSN--QFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYY----SSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQE-------------------------------------------------DAFHPRELNAEPSQMQIPKETKAEDEDIVLTPD--GTREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMS-TEGNKRGMIQLIVARRISKCNELK--------------------------------SPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALS-RIMGESGKYQLSPTVNMPQ----------------------------------------------------DDTVIIEDDRLPVLP-----PHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSL-----------SPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTR-----KSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRP-RIIRGRGCNESFRAAIDKSYDKPAVDDDDE-GMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKG-MLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHR---TFGCDDELMYGGVSSYEG--SMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9K4-1", "uniprot_id": "A0AB13A9K4_DANRE", "id": "A0AB13A9K4-1", "name": "", "aln": "--------------------MKVTVCFGRTRVVVPCGDGNIKVQSLVQQAAMRYRRAIAKGEEYWVQVYRLEHGDGGILDLDDVLCDVADDKDRLVAVFDEQEP-----HVGGDGTS-ASSTGTQSPELYCGEPSTSTPLSAFQPYLPHSEIEVTTS--TLRTNMPLHVRRSSDPALLNLTAMSFSEPGSQPEEPSRKNPTRWSTTAGFLKPRFATGTNSLERKGRGVDTYRSLPRDAGQWSNQKEFQREKARSSLSANHPMVDRWLERQEQD----EEENGRIEPVGRADTCLEHMGVRSLDDIVKLVEVSNDGGPLGIHVVPFSGRDRRTLGLLVKRLERGGKADVQGLFQENDCIIRINNGDLRNVRFEQAQNMFRQAMRSPVILFHVVPTTMRSQYEQISHNEHNPRANIDLSGRFSPDSLTNDLDSAAHRLAQHRP-----QQPNNHLDTGSPVHHLVGSSGKPPTGHTSSPQRGLSPAPTTGF-TKKVGRRLGIQLKKGPEGLGFSITSRDVPLGGSAPIYVKNILPRGAAIQDGRLKAGDRLLEVNGVDLNGRGQEEVVSLLRATPMGGTVTLVVLRQE-------------------------------------------------ETFIPREMNAEP-AIQNTREWKVEEEELVLTPD--GTREFLTLEVPLNDSGSAGLGVSVKGNRSK-----------------ESHADLGIFVKSIINGGAACKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRKSMS-TEGNKRGMIQLIVARRINKRLEGE--------------------------------SRGSPRGLERTLSPSPDDHERRISHSLY-GIEGLDDNLRPQASTNNRKMN---HYQLSPTVNMPQ----------------------------------------------------DDTVIIEDDRPHVLP-----IQLSDQSSSSSHDDMGFAVETP--PPPPWEPELPDSSS-----------SANAEG--QFQREGFGRQSMSEKRTKQYGDAGQLDIIKTR-----KSKSMDL----------------GSSTRDVGPSLGLKKSSSLESLQTAVAEVTLNGDMPFHRPRP-RIIRGRGCNESFRAAIDKSYDRPAANEDEEECMDTLEEDTEGSSRSGRDSVSTVADLTPLPVTEQQLINGNQPE-NDKKKEKGGKDKKK---PEKEKGKTKKG-MLKGLGEMFRFGKYRKDERLDG-AKWKAEETHASEEETRRMKQEQERIQAKTREIRQRQARERDYAEIQDFSRSTLTSLPPEEPPYAGIGSLEHGGYHRIHTPPDSP---------YTQKQNGRNGHPS--TSDRLTPSNHDRIQRLRQEFQQVRQEETEPDDRHRSYSMEQPWSNCSSQSSSGRHSVSVEVQLQR--QEARDAFTHAQRQYSSLPRHPRKTPTPASESEWERTGPSVDAFQAAKDSGRYSSYQGPRSVPRTVPRHGCRNGFSAAPGSSSSSVGSGYNARVLLEAQELLRQEQRRREQEMKGRGPSIR----------VDYECQDSKGPQRQDVPPSPSQVVRLSRIHTPEKTRPFLS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHR3-1", "uniprot_id": "Q0KHR3_DROME", "id": "Q0KHR3-1", "name": "", "aln": "MFDVPPKCPALANKLGGLFGWRHTYKVAAKQEGIPHGQLHKSYSLTLPKRPPSPSTYSCVKPDSWVTVTHLQTQSG-ILDPDDCVRDVADDREQILAHFDDPGPDPGVPQGGGDGASGSSSVGTGSPDIFRDPTNTEAPTCPRDLSTPHIEVTSTTSGPMAGLGVGLMVRRSSDPNLLASLKAEGSN-------------KRWSAAAPHYAGGDSPERLFLDKAGG---------QLSPQWEEDDDPSHQLKEQLLHQQQPHAANGGSSSGNHQPFARSGRLSMQFLGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQ-NGAYSSKSLPRESKRKEPLGQAYESIREKDGEMLLIIN-----EYGSPLGLTALPDKEHGGGLLVQHVEPGSRAERGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSELRVR-----VLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDSLPPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGRKILRSASSSDILDHSNSHSHSHSNSSGGSNSNGSGNNNNSSSNASDNSGATVIYLSPEKREQRCNGGGGGGSAGNEMNRWSNPVLDRLTGGICSSNSAQPSSQQSHQQQPHPSQQQQQQRRLPAAPVCSSAALRNESYYMATNDNWSPAQMHLMTAHGNTALLIEDDAEPMSPTLPARPHDGQHCNTSSANPSQNLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETNSGVEHFSRDALGRRSISEKHHAALDARETGTYQRNKKLREERERERRIQLTKSAVYGGSIESLTARIASANAQFSGYKHAKTASSIEQRETQQQLAAAEAEARDQLGDLGPSLGMKKSSSLESLQTMVQELQMSDEPRGHQALRAPRGRGREDSLRAAVVSEPDASKPRKTWLLEDGDHEGGFASQRNGPFQSSLNDGKHGCKSSRAKKPSILRGIGHMFRFGKNRKDGVVPVDNYAVNISPPTSVVSTATSPQLQQQQQQQLQQHQQQQQIPTAALAALERNGKPPAYQPPPPLPAPNGVGSNG---IHQNDIFNHRYQHYANYEDLHQQHQQHQISGGDSTTSISETLSESTLECMRQQVIRQRIKVEAESRRHQHYHSQRSARSQDVSMHSTSSGSQPGSLAQPQAQSNGVRPMSSYYEYETVQQQ-RVGSIKHSHSSSATSSSSSPINVPHWKAAAMNGYSPAS-------------------------LNSSARSRGPFVTQVTIREQSSGGIPAHLLQQHQQQ------------------QLQQQQPTYQTVQKMSGPSQYGSAAGSQPHASKV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. .: :* *: . . : : . : *: * :*: .* *** ** : *****:::::* **: * : ****:* :* .** **::: . .*. .. . *: *.* .: * ******* * . *: .***::* . : :: : . .*.: : .:: .. * .:* . . . . :. .. :: :* .: .*:: :. ::*. . * .. . ::* ** * *:* . ::.: :: ** : . : : : : .: * . : : :: : : :: .. . :: : . .. . : * *:::*::: * ****.:*****:*:** . ** .***:**********:*****.****:**:*. : *: * :**::**. .** ::* **: ::* . :: * ..::.: :.: :** **:.:*::*: .*********: .. : ..*******.:*:****.:*****:****::*** ** *: * :******::* * *:: * * *:*.*:* : . * .* . : :.:*:* . . * * : . :. . . . .*: : .: : :::**** : * : .::..:** : . . .. * . *.*:.:**:*:***: . :.: :.:. : . . * *::.: .*:: :: * . . * : : . * ::* :: : .*: ::*. . ... :. . .. . : :: ::: :.. : .. ::** :*:*:*.****** *** : .. :* . : *:: * : :: :::* : : . . : : : * :: :. . :. . ... :: :**:. : : . . *:: * ::. . * . . * *. : :*.:: :: * . *... . .. . . ..*. . . . .:* : :* :*::. : : :* . : .:: .: :. :*. * ", "identical_positions": 247, "similar_positions": 404, "identity": "15.43%" }, { "cls_id": "homologset.agr.MGI:2135609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14910-1", "uniprot_id": "LIN7A_HUMAN", "id": "O14910-1", "name": "Protein lin-7 homolog A", "aln": "MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZS0-1", "uniprot_id": "LIN7A_MOUSE", "id": "Q8JZS0-1", "name": "Protein lin-7 homolog A", "aln": "MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQPQQNHMS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z250-1", "uniprot_id": "LIN7A_RAT", "id": "Q9Z250-1", "name": "Protein lin-7 homolog A", "aln": "MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQ-PQQNHMS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BC73-1", "uniprot_id": "A0A8M2BC73_DANRE", "id": "A0A8M2BC73-1", "name": "Protein lin-7 homolog", "aln": "-------------MATVT-VQPLTLERDVTRAIELLEKLQESGDVPGHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEYQARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQILMQQQQQ-QNLAAQQNHMSLFQKKKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMT8-1", "uniprot_id": "Q8IMT8_DROME", "id": "Q8IMT8-1", "name": "Protein lin-7 homolog", "aln": "-------------MADNA--EPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : :****.*** *:******** **:.* ** :*:***:*:* *::****::::**: ::*. : :* ****************:**********:** **************************:**********************:********* * .***************** **:* *.:**** ", "identical_positions": 149, "similar_positions": 30, "identity": "51.2%" }, { "cls_id": "homologset.agr.MGI:2135610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXU8-1", "uniprot_id": "DC1L1_RAT", "id": "Q9QXU8-1", "name": "Cytoplasmic dynein 1 light intermediate chain 1", "aln": "MAAVGRVGSFGSSPPGLASTYASGPLANELASGSGGPAAGDDEDGQNLWSRILREVSTRSRSKLPTGKNVLLLGEDGAGKTSLIRRIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYHKGLLKFSLDALSLRDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKEMEQKLIRDFQEYVEPGEDFPASPQRRATAAQEDRDDSVVLPLGADTLTHNLGLPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKIEDNFEDIITKPPVRKFVH--EKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGS-PRTPNRSVSSNVASVSPIPAGSKKIDPNMK-AGATSEGVLANFFNSLLSKKTGSPGGPGV-GGSPGGGAAGASTSLPPSAKKSGQKPVLSDVHAELDRITRKP--ASVSPTTPPSPTEGEAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1Q8-1", "uniprot_id": "DC1L1_MOUSE", "id": "Q8R1Q8-1", "name": "Cytoplasmic dynein 1 light intermediate chain 1", "aln": "MAAVGRVGSFGSSPPGLASTYASGPLANELASGSGGPAAGDDEDGQNLWSCILSEVSTRSRSKLPTGKNVLLLGEDGAGKTSLIRRIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYHKGLLKFSLDALSLRDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKEMEQKLIRDFQEYVEPGEDFPASPQRRTTGAQEDRGDSVVLPLGADTLTHNLGLPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKVEDNFEDIITKPPVRKFVH--EKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGS-PRTPNRSVSSNVASVSPIPAGSKKIDPNMK-AGATSEGVLANFFNSLLSKKTGSPGGPGV-GGSPGGGAAGASPSLPPSAKKSGQKPVLSDVHAELDRITRKP--ASVSPTTPTSPTEGEAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6G9-1", "uniprot_id": "DC1L1_HUMAN", "id": "Q9Y6G9-1", "name": "Cytoplasmic dynein 1 light intermediate chain 1", "aln": "MAAVGRVGSFGSSPPGLSSTYTGGPLGNEIASGNGGAAAGDDEDGQNLWSCILSEVSTRSRSKLPAGKNVLLLGEDGAGKTSLIRKIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYHKGLLKFSLDAVSLKDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKQMEQKLIRDFQEYVEPGEDFPASPQRRNTASQEDKDDSVVLPLGADTLTHNLGIPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKAEDNFEDIITKPPVRKFVH--EKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGS-PRTPNRSVSSNVASVSPIPAGSKKIDPNMK-AGATSEGVLANFFNSLLSKKTGSPGGPGVSGGSPAGGAGGGSSGLPPSTKKSGQKPVL-DVHAELDRITRKP--VTVSPTTPTSPTEGEAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUM9-1", "uniprot_id": "Q1LUM9_DANRE", "id": "Q1LUM9-1", "name": "Dynein light intermediate chain", "aln": "MATTGRN--------TLLSVSTN---VNNSTSESQNP---EEEDGQNLWSSILSEVSTRSRSKLPSGKNVVVMGEVGSGKTTLVAKLQGVEEYMKGRGLEYLYFNVHDDDIDDQSRCNAWVLDGDLYHKGLQKFAISLENLEDSLILFVVDLSRPWLALDSLQKWGSVVRDFVDKLRVPPETMRELEHRLTKQFQEYVEPGSDLDAVPQRRNPESDE---ESVLLPLGENTLTHNLGLPIVVVCTKCDAISTLEKEHDYKDEHLDFIQSHIRRFCLQYGAALLYTSMKENKNLDLLYKYLVHRLYGFPFNSPAQVVEKDSVFIPSGWDNEKKIAILHENFQMVKAEDSFEDVIVKPPVRKFVH--EKEVQAEDDQVFLVKLQSLLSKQPPVTAGRPVDPTNRAPTGS-PRTTNRSAAANVANVMPMQSGTKKIDPNMK-GGQTSEGVLANFFNSLLTKKAGSPG--------PGGQPAGGGSNTPGTVRKSGSKLGLTDVQAELDRISNKSDLDSSAPNATTPPAENDKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ20-1", "uniprot_id": "Q9VZ20_DROME", "id": "Q9VZ20-1", "name": "Dynein light intermediate chain", "aln": "------------------MAMNSGTQTNALTSSFTMKKKDAAAEKENLWSAILNEVQTQGSTKLPSNKSVLVLGDNATGKTTLIAKLQGVEDPKKGSGLEYAYIDVKDEYRDDMTRLGVWVLDGDPGHTNLLHYALNETNYAHTLVILTVSMTQPWGWLEQLNHWIKVLGQHIDSLQLDAKEKEAARQRLTTTWQSYCEVGDDLDPGSPVKRTMRNNSIDEDDLLPLTEDALITNLGLDIVVVVTKTDYMTTLEKEYEYRDEHFDFIQQWIRNFCLRHGTSLFYTSVKEDKNCDVLYKYLTHRIYGLPFRTPALVVEKDAVLIPAGWDSLKKISILYENMHGVKAENPYTDIIKSPPTRKAVSNREAEVQTEDEQAFLARQQEILKQGDQVRGESPLRSQGVGSNKSGPRTPGTTGQS----------SPKKIDPKLTPATPGAEGVLANFFNSLLHKKSGSPGTGGP-GGAGNPAGPGRTANGTDAVMTPEKLAVRTDAAAELDRLSR-----SVKKEIDMSQSEC---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :* : :**** ** **.*:. :***:.*.*:::*: .:***:*: ::**:*: ** **** *::*:*: ** :* ..*:**** *..* ::::. . .:*:::.*.:::** *:.*::* .*: :.:*.*:: .: . .::* :*.* * *.*: . . : . :: :. :*** ::* ***: ::** ** * ::.****::*:***:****. **.***::*::*:***:**:** *::***:.:::**:*:. ** *****:*:**:***. ***.**:**:: :* *: : *:* .**.** * * *: :**:*.** : *.:* : . . *: . . * ***.. : : ..*****::. . :************ **:**** * .. . :. .. . *. *****::. : . :* ", "identical_positions": 178, "similar_positions": 166, "identity": "33.58%" }, { "cls_id": "homologset.agr.MGI:2135611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF12-1", "uniprot_id": "A0ABK0LF12_RAT", "id": "A0ABK0LF12-1", "name": "Mitochondrial inner membrane protease subunit", "aln": "MAQSQGWVRRCFKAFCKGFFVAVPVAVTFLDRVVCVARVEGSSMQPSLNPGGS-QSSDVVLLNHWKVRN-FEVQRGDIVSLVSPKNPEQKIIKRVIALEGDIIRP-IGYKNQLVKVPRGHMWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERSPVH----TSEE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPT6-1", "uniprot_id": "IMP2L_MOUSE", "id": "Q8BPT6-1", "name": "Mitochondrial inner membrane protease subunit 2", "aln": "MAQSQSWARRCFKAFCKGFFVAVPVAVTFLDRVACVARVEGSSMQPSLNPGGS-QSSDVVLLNHWKVRN-FEVQRGDIVSLVSPKNPEQKIIKRVIALEGDIVRT-IGHKNRLVKVPRGHMWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQRLESVLPPERCPLQ----TGEK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T52-1", "uniprot_id": "IMP2L_HUMAN", "id": "Q96T52-1", "name": "Mitochondrial inner membrane protease subunit 2", "aln": "MAQSQGWVKRYIKAFCKGFFVAVPVAVTFLDRVACVARVEGASMQPSLNPGGS-QSSDVVLLNHWKVRN-FEVHRGDIVSLVSPKNPEQKIIKRVIALEGDIVRT-IGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQ----REEE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AZD4-1", "uniprot_id": "IMP2L_DANRE", "id": "Q6AZD4-1", "name": "Mitochondrial inner membrane protease subunit 2", "aln": "MAQT-GFGRRYFKAFVSGFFVAVPVTVTVLDRLAYVARVEGASMQPSLNPDGE-SSPDVVLLNRWSVRN-YHVQRGDIVSVLSPKNPQQKIIKRVIGIEGDFIKT-LGYKNRYVRVPDGHLWIEGDHHGHSFDSNAFGPVSLGLVHGRASHIIWPPSRWQRIEPSVPPDRRPLLNWDRAAEDKYDDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46972-1", "uniprot_id": "IMP2_YEAST", "id": "P46972-1", "name": "Mitochondrial inner membrane protease subunit 2", "aln": "MFRA-GSSKRFLRNTLIAIS-WVPVLLTINNNVVHIAQVKGTSMQPTLNPQTETLATDWVLLWKFGVKNPSNLSRDDIILFKAPTNPRKVYCKRVKGLPFDTIDTKFPYPKPQVNLPRGHIWVEGDNYFHSIDSNTFGPISSGLVIGKAITIVWPPSRWG-TDLKLSTGRDCIS--KRAILE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: . :* :: .: *** :*. :.:. :*:*:*:****:*** . :.* *** :: *:* .: *.**: . :*.**.: *** .: * : . : : : *.:* **:*:***:: **:***:***:* **: .:* *:***.** : :.. * : . ", "identical_positions": 59, "similar_positions": 61, "identity": "31.55%" }, { "cls_id": "homologset.agr.MGI:2135625", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESH6-1", "uniprot_id": "GLRX1_RAT", "id": "Q9ESH6-1", "name": "Glutaredoxin-1", "aln": "MAQEFVNCKIQSGKVVVFIKPTCPYCRKTQEILSQLPFKRGLLEFVDITATNNTNAIQDYLQQLTGARTVPRVFIGKDCIGGCSDLLSMQQNGELTARLKQIGALQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUH0-1", "uniprot_id": "GLRX1_MOUSE", "id": "Q9QUH0-1", "name": "Glutaredoxin-1", "aln": "MAQEFVNCKIQSGKVVVFIKPTCPYCRKTQEILSQLPFKQGLLEFVDITATNNTSAIQDYLQQLTGARTVPRVFIGKDCIGGCSDLISMQQTGELMTRLKQIGALQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35754-1", "uniprot_id": "GLRX1_HUMAN", "id": "P35754-1", "name": "Glutaredoxin-1", "aln": "MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********.***************::********:*:************:*. ******************************:*:**.*** :********* ", "identical_positions": 93, "similar_positions": 11, "identity": "86.92%" }, { "cls_id": "homologset.agr.MGI:2135637", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88767-1", "uniprot_id": "PARK7_RAT", "id": "O88767-1", "name": "Parkinson disease protein 7 homolog", "aln": "---------------------------MASKRALVILAKGAEEMETVIPVDIMRRAGIKVTVAGLAGKDPVQCSRDVVICPDTSLEEAKTQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAHEVGFGCKVTSHPLAKDKMMNGSHYSYSESR-VEKDGLILTSRGPGTSFEFALAIVEALSGKDMANQVKAPLVLKD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LX0-1", "uniprot_id": "PARK7_MOUSE", "id": "Q99LX0-1", "name": "Parkinson disease protein 7 homolog", "aln": "---------------------------MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVMICPDTSLEDAKTQGPYDVVVLPGGNLGAQNLSESPMVKEILKEQESRKGLIAAICAGPTALLAHEVGFGCKVTTHPLAKDKMMNGSHYSYSESR-VEKDGLILTSRGPGTSFEFALAIVEALVGKDMANQVKAPLVLKD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99497-1", "uniprot_id": "PARK7_HUMAN", "id": "Q99497-1", "name": "Parkinson disease protein 7", "aln": "---------------------------MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENR-VEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJ36-1", "uniprot_id": "PARK7_DANRE", "id": "Q5XJ36-1", "name": "Parkinson disease protein 7 homolog", "aln": "---------------------------MAGKRALVILAKGAEEMETVIPVDVMRRAGIAVTVAGLAGKEPVQCSREVMICPDSSLEDAHKQGPYDVVLLPGGLLGAQNLSESPAVKEVLKDQEGRKGLIAAICAGPTALLAHGIAYGSTVTTHPGAKDKMMAGDHYKYSEAR-VQKDGNVITSRGPGTSFEFALTIVEELMGAEVAAQVKAPLILKD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9J4-1", "uniprot_id": "DJ1A_DROME", "id": "A1Z9J4-1", "name": "Protein DJ-1alpha", "aln": "MLSVLRKSFPNGVTHAHRVIRCKSNQDKCAKNALIILAPGAEEMEFTISADVLRRGKILVTVAGLHDCEPVKCSRSVVIVPDTSLEEAVTRGDYDVVVLPGGLAGNKALMNSSAVGDVLRCQESKGGLIAAICAAPTALAKHGIGKGKSITSHPDMKPQLKE--LYCYIDDKTVVQDGNIITSRGPGTTFDFALKITEQLVGAEVAKEVAKAMLWTYKP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA37-1", "uniprot_id": "DJ1B_DROME", "id": "Q9VA37-1", "name": "Protein dj-1beta", "aln": "----------------------------MSKSALVILAPGAEEMEFIIAADVLRRAGIKVTVAGLNGGEAVKCSRDVQILPDTSLAQVAS-DKFDVVVLPGGLGGSNAMGESSLVGDLLRSQESGGGLIAAICAAPTVLAKHGVASGKSLTSYPSMKPQLVN--NYSYVDDKTVVKDGNLITSRGPGTAYEFALKIAEELAGKEKVQEVAKGLLVAYN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* **:*** ****** *..*::**. * ****** . :.*:***.* * **:** :. . . :***:**** * : : :*. * ::*: **. ********.**.* * :. * .:*::* * :: * * : : * :** ::*******:::*** *.* * * : . :* :: ", "identical_positions": 82, "similar_positions": 51, "identity": "37.44%" }, { "cls_id": "homologset.agr.MGI:2135671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0D3-1", "uniprot_id": "LMOD1_RAT", "id": "A0A0G2K0D3-1", "name": "Leiomodin-1", "aln": "MS-KVAKYRRQVSEDPDIDSLLSTLSPEEMEELEKELDVVDPDGSIPVGLRQRNQTDKQPSGSFNREAMLNFCEKESKKIIQREMSVD--ESKQVGRKTDAKNGEDKGSNASRKALGPRQDSDVGKEPKKGVLKKSFSRDR-EEADSRGSEKPKEEKVIRGIDKGRVR----AAVDRKEAGKDGREERAAATTKKEEEKTGSVRNAGLSRDK--DKKREEVKEP---SKKEE-VKLTAENRSTVGRQEDGKQKESREDRDKKPEVK--GIGCGSRDSRKEDEKVKKEETQPDKGVR---EEGKTR--EKQPPSGPSKPSDG-QARAEEEAAPSIFDEPLEKVKNNDPEMTEVNVNNSDCITNEILVRFTEALEFNTVVKVFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHITGKGILAIFRALLQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTNLLSRNMDKQRQKRLQEQKQA---QEASGEKKDRLEVPKVGALPKGSPK-----------PSPQPSPKSAPKN-----------SPKK--AGVPAAPPPPPPPLAPPLIMENLKNSLSPATQRK-MGDKVLPAQEKNSRDQLLAAIRSSNLKQLKKVEVPKLLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVA4-1", "uniprot_id": "LMOD1_MOUSE", "id": "Q8BVA4-1", "name": "Leiomodin-1", "aln": "MS-KVAKYRRQVSEDPDIDSLLSTLSPEEMEELEKELDVVDPDGSIPVGLRQRNQTDKQPSGSFNREAMLNFCEKESKKLIQREMSVD--ESKQVGRKTDAKNGEEKDSDASRKAPGPRQDSDLGKEPKKGVLKKSFSRDR-EEADGRGGEKPKEEKVIRGIDKGRVR----AAVDRKESGKDGREERAAAARK-EEEKTGSVKNAGLSRDK--DKKKEEVKEP---SKKEE-VKLTAESRNTVGRREDGRLKESSKE-NKKPEDE--GIGSGGRDWRKEDEKVKKEENQPDKEVR---EESKTKAPEKQAPSCPNKPSDG-QARAEEEAAPSIFDEPLEKVKNNDPEMTEVNVNNSDCITNEILVRFTEALEFNTVVKVFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHITGKGILAIFRALLQNNTLTELRFHNQRHICGVKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTNLLSRNMDKQRQKRLQEQKQA---QEASGEKKDRLEVPKVGALAKGSPK-----------PSPQPSPKPAPKN-----------SPKK--AGVPAAPPPPPPPLAPPLIMENLKNSLSPATQRK-MGDKVLPAQEKNSRDQLLAAIRSSNLKQLKKVEVPKLLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29536-1", "uniprot_id": "LMOD1_HUMAN", "id": "P29536-1", "name": "Leiomodin-1", "aln": "MS-RVAKYRRQVSEDPDIDSLLETLSPEEMEELEKELDVVDPDGSVPVGLRQRNQTEKQSTGVYNREAMLNFCEKETKKLMQREMSMD--ESKQVETKTDAKNGEERGRDASKKALGPRRDSDLGKEPKRGGLKKSFSRDR-DEAGGKSGEKPKEEKIIRGIDKGRVR----AAVDKKEAGKDGRGEERAVATKKEEEKKGSDRNTGLSRDK--DKKREEMKEV---AKKEDDEKVKGERRNTDTRKEGEKMKRAGGNTDMKKEDEKVKRGTGNTDTKKDDEKVKKNEPLHEKEAK---DDSKTKTPEKQTPSGPTKPSEG-PAKVEEEAAPSIFDEPLERVKNNDPEMTEVNVNNSDCITNEILVRFTEALEFNTVVKLFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHITGKGILAIFRALLQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTNLLSRNMDKQRQKRLQEQRQA---QEAKGEKKDLLEVPKAGAVAKGSPK-----------PSPQPSPKPSPKN-----------SPKK--GGAPAAPPPPPPPLAPPLIMENLKNSLSPATQRK-MGDKVLPAQEKNSRDQLLAAIRSSNLKQLKKVEVPKLLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRG4-1", "uniprot_id": "A0A8M9PRG4_DANRE", "id": "A0A8M9PRG4-1", "name": "Leiomodin-3", "aln": "MSRRTARERQESDDDSDTDLLLAALSPEEVEKLERELVYIDPDPTVPVGLRQRNQTDKLPSRGYDREAMLDYCERQTKKLIRRELSAEGGDGRRRERLRRMRSREFSRSQSGDPPDTESRNAESEKDKERTRKWEDDSKDLSDEGKNKREEKRTGDKMESGKELSRKEKGGSKTLDLISKLQEKQEEKKDRGRKDDKKVNENSKIRGVVSKLQGNKVTEEKKDKKTDVKQQDGSRTKASEVPKNNKAGRVNLIDAEKDDKNSRFSTVEETSLDKTRPQKEREQVKAPENSKAKIFTSSFHESSGNCHGADTCSLTTEEDESYSEDLDSDTGSSMFDDLLEQVRSDDPELTEVNVNNSDAIKTDTLIQFAEGLRSNTHIKTFCLANTRADDHVAFAIAKTLRENSTLTGINLDSNHLTGKGILAIINSLQHNSALMELRFHNQRHICGGKTEMEMAKVLRDNSSLLKLGYHFELAGPRMAMTNILSRNMDRKRQQRLEAQKLAGHEINSTAREENKSSTNKANSKTLSTPKKDSKFASLSKFTSAQENSKASPTKPLSKLLTTEVTGSKKGATGCGQAPPPPPPPPGPALDVQALRRSLTPVSQRKPDGSTAVRQTDRSSRDQLLDSIRNCSMNALKKVEIPKRLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.*: *:: .:*.* * ** :*****:*:**:** :*** ::**********:* .: ::*****::**:::**:::**:* : :.:: :. * ::. . :::: *: :: :. *:* :*. .: ** . :*: * : .* . ::* . :: : *. * ::: . . : *: . :* ** *: *::: : ... . : . : : . . . . :*: *:** * * .:.. . :. * ..: .:. :.::..*:**: **:*:.:***:*********.*..: *::*:*.*. ** :* *.*************** *: *.*:*.:******:********:.:* :*.:* ************ *****:**:*::*::***************::**:******::**:**: *: * ::...::: .. *..: . .:** .*.* ..*.:*.: ..** * ******** .*.* :: *:.**:*.:*** *...: ::.****** :**...:: *****:** *:", "identical_positions": 228, "similar_positions": 209, "identity": "35.35%" }, { "cls_id": "homologset.agr.MGI:2135672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UHZ5-1", "uniprot_id": "LMOD2_MOUSE", "id": "Q3UHZ5-1", "name": "Leiomodin-2", "aln": "---------------------------------MSTFGYRRGLSKYESIDEDELLASLSPEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGNFSREALMAYWEKESQKLLEKERLGECGKVAEEDKEESEEELIFTESNSEVSEEVCTEDEEESQ------EEEEDSEEEEDSEEEEETTEATKHINGTVSYNSVNTDNSK-----PKT---FKSQIENINLTNGNSGRTQRNSESPAAIHP-----CGNPTVIEDALEKIRNNDPDTTEVNLNNIENITTQTLSRFAEALKENTVVKTFSLANTHADDAAAIAIADMLKVNEHITSVNVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRMQEQKQQEGHDGGAA-LRTKVWQRGTPGSSPYASPRQSPWSSPKVSKKVHTGRSRPPSPVAPPPPPPPPPLPP----HMLPPPPPPPAPPLPEKKLITRNIAEVIKQQESAQR-ALQNGQRKKKGKKVKKQP------NNILKEIKNSLRSVQEKKMEDSSRPSTPQRSVHENLMEAIRGSSIRQLRRVEVPEALR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1A5Q0-1", "uniprot_id": "LMOD2_RAT", "id": "A1A5Q0-1", "name": "Leiomodin-2", "aln": "---------------------------------MSTFGYRRGLSKYESIDEDELLASLTAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGNFSREALMAYWEKESQKLLEKERLGECGKLAEEDKEESEEELIFTESNSEVSEEVCTEEEEEST------EEEEE-EEEEDSEEEEVTTEVTKHINGTVSHNGVNPDNSK-----PKT---FKSQIENINLTNGNSGGTQRNTESPAAIHP-----CGNPTVIEDALEKIKNNDPDTTEVNLNNIENITTQTLSRFAEALKENTVVKTFSLANTHADDAAAIAIAEMLKVNEHITSVNVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRMQEQKQQEGHDGGAT-LRTKVWQRGTPGSSPYASPRQSPWSSPKVSKKVHTGRSRPPSPVAPPPPPPPPPLPP----HMLPPPPPPPAPPLPGKKLITRNIAEVIKQQESAQR-ALQNGQRKKKGKKVKKQP------NNILKEIKNSLRSVQEKKMEESSRPSTPQRSAHENLMEAIRGSSIRQLRRVEVPEALR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5Q4-1", "uniprot_id": "LMOD2_HUMAN", "id": "Q6P5Q4-1", "name": "Leiomodin-2", "aln": "---------------------------------MSTFGYRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGTFSREALMAYWEKESQKLLEKERLGECGKVAE-DKEESEEELIFTESNSEVSEEVYTEEEEEES------QEEEE---EEDSDEEERTIETAKGINGTVNYDSVNSDNSK-----PKI---FKSQIENINLTNGSNG---RNTESPAAIHP-----CGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRLQEQKQQEGYDGGPN-LRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQR-ALQNGQKKKKGKKVKKQP------NSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRVEVPEALR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5L7-1", "uniprot_id": "F1Q5L7_DANRE", "id": "F1Q5L7-1", "name": "Leiomodin-2", "aln": "MSTHSHLNHSKDPRTLKTSDAPTLRQNQDYQEAMSTFGYRRELSKYEDLDEDELLASLTAEELQELEKELADIDPDDNLPIGLRQRDQTAKTPTGTFSREALMKYWENETRKLLEEERIGST-SPGEKDKDSREEEECVTESDTEDSGDEKDEVEESEKDTEKYREAEEDREEEEESEADEPVTEEEEEEEEEEEDDKEEQEEQKEIDNHPKMGHSMECNTQPQHCWSSNSQSNQRQIGEPKAQSQEPGRTSGNPTVADEVLEKVLNNDPETTEVNLNNIDNISQDTLIRFAEALRSNAQVRVFSLANTHADDQVAFAIAKMLRENRNITNLNIESNFITGKGILALVQAITQNNTLTEMRFHNQRHICGGQVEMEIVKLLRENTTLIKLGYQFDLPGPRISMTTLLTRNQDLQRQKRMQELRLQNGGTATPTNPRTVALQKSTSTSSPHSSPRSSPWSSPKLPHVDMAKKN------APPAPPPPPPPPP-------PPPPPPPKASLSENKPPSRMIAEVIKRQEETSK-KQQHGPTKSKSKKGKKRPPNQTETDSILKELKNALRPINDR---ENSRPSTPQRCAHDELMAAIRGSSVRNLRRVEVPKYLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8RJX3-1", "uniprot_id": "A0A2R8RJX3_DANRE", "id": "A0A2R8RJX3-1", "name": "Leiomodin-3", "aln": "---------------------------------MSTSGYRKGLGKHEEIEEDELLASLTSEELQELEKIMAEMEPDENIPIGLQQEDQTAKKSTGTFCRGSLLKYWEDETQRLLKDS---------------------MDECQTDKCEEECASEEPEDN----------------KEKGGDRVKQARSNKWNSVELSRLDSESAR------------KYNDAPHYPVTLDGS-------------------SCNPTDIDKTLEHVLSNATSLTEVNLNNVENLSQGVLVGFADALTSNTHVEVFNLANTHADDQVALALAKMLKANSSITRLNVESNFISGKGILALIKSLQYNNTLTELRFHNQRHICGGQVEMEMVKLLKDNTSLLKLGYHFELPGPRMSATGILTRNQDRHRQKRLQERREKDKSQ-----EQVKSWNTVDKMQSFQFQISTDKHTTQGKQHLVSS-----------------------------YLPQPPHNQPNGVMNVPMRQIAETVKQQETENVGRIQANSNKKHNLTGDKHG-------------KKKLHDDNTEHSRRKDDLNSLEESTRDDLLAAIRGSNIGSLRRVKS-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ***: *.*:*.::********:.***:***: : :::** *:*:**:*.. * *..**.*.* :*: ***.*:::**:.. . *.::: . : . * .. ... : . : . . . : :. : : : . .. . *** :..*::: .* .. *******::*:: .* **:** .*: *..*.******** .*:*:*.**: * ** :*:*****:******::::: *..***:******** *.*****:****::**:*::***:*:*****:* * :**** * :****:** : :: :. : .* . . :: : : * ** . : * ***.:*:** . * . *.:. . .*: *: *: : . .. .: :...:::*: *****.: .*:**: ", "identical_positions": 166, "similar_positions": 157, "identity": "27.04%" }, { "cls_id": "homologset.agr.MGI:2135679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BYE0-1", "uniprot_id": "HES7_HUMAN", "id": "Q9BYE0-1", "name": "Transcription factor HES-7", "aln": "--------------------------------MVT-RDRAENRDGPKMLKPLVEKRRRDRINRSLEELR---------LLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPP--------------------------------------------------------------------------------------------------------GVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BKT2-1", "uniprot_id": "HES7_MOUSE", "id": "Q8BKT2-1", "name": "Transcription factor HES-7", "aln": "--------------------------------MVT-RERAENRDGPKMLKPLVEKRRRDRINRSLEELR---------LLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPP--------------------------------------------------------------------------------------------------------GVPRSPGQDAEALASCYLSGFRECLLRLAAFAHDASPAARSQLFSALHGYRRPKPPRPEAVDPGLPAPRPPLDPASPILGPALHQRPPVHQGPPSPRLAWSPSHCSSRAGDSGAPAPLTGLLPPPPPPYRQDGAPKAPSLPPPAFWRPWP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LCP7-1", "uniprot_id": "A0ABK0LCP7_RAT", "id": "A0ABK0LCP7-1", "name": "", "aln": "MSFSSTVVFTIRVAVSYTSHAGNWFHSLRLDSLVSGWDRDLSRSSPHSVASPGGTRS-SRIRPSLLPLATFPLSPHPFLSLRPSPRLQNLRNPKLEKAEILEFAVGYLRERSRVEPPGTARGVGQRREAGGWGARNARAGEGAGSEVDRGVGERPAVLPDEVNNTRACLSLCLPRCPPLHVHPASCLCLCARLTSVSLRPAPSLNPVGPLPRPPVLPPAAPGVPRSPGQDAEALASCYLSGFRECLLRLAAFAHDASPAARSQLFSALNGYRRPKPPRPEAADPGLPAPRPPLDPASPILGPALHQRPPVHQGPPSPRLAWSPSHCSPRAGDSGAPAPLTGLLPPPPPPYRQDGAPKAPPLPPPAFWRPWP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :* .*..*: : . .* .**. ** * * * .* ****************************** ****** *********************************:******:** *******:..** *****.****:* ************** **** ***** **.*********************:********* **********", "identical_positions": 174, "similar_positions": 22, "identity": "46.9%" }, { "cls_id": "homologset.agr.MGI:2135738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CFC4-1", "uniprot_id": "BGAT2_RAT", "id": "Q8CFC4-1", "name": "Histo-blood group ABO system transferase 2", "aln": "---MKDLRFGRLKCYSLHLGILPLTVLVLVFFCFVCLSLRSQEWGHPG----------------AVNRKAYPQPRVLTPTRTDVLVLTPWLAPIIWEGTFDIDTLNEQFRLRNTTIGLTVFAVKKYVVFLKLFLETAEQHFMVGHKVIYYVFTDRPADVPQVPLGAGRRLVVLTVRNYTRWQDVSMHRMEVISHFSEQRFRHEVDYLVCADVDMKFRDHVGVEILSALFGTLHPGFYRSRRESFTYERRPQSQAYIPWDQGDFYYMGAFFGGSVVEVHHLTKACHQAMVEDQANGIEAVWHDESHLNKYLLYHKPTKVLSPEYMWDQQLLGWPSIMKKLRYVAVPKNHQAIRN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET32-1", "uniprot_id": "BGAT1_RAT", "id": "Q9ET32-1", "name": "Histo-blood group ABO system transferase 1", "aln": "----MDLR-GRPKCYSLHLGILPFIVLVLVFFGYGFLSHKIQEFRNPGGETCMATRQTDVQKVVSVPRMAYPQPNVLTPIRNDVLVFTPWLAPIIWEGTFNIDILNEQFKLQNTTIGLTVFAIKKYVVFLKLFLETAEQHFMVGHKVIYYVFTDRPSDVPQVPLGAGRKLVVLTVRNYTRWQDVSMHRMEMISHFSEQRFQHEVDYLVCGDVDMKFSDHVGVEILSALFGTLHPGFYRSRRESFTYERRPKSQAYIPRDEGDFYYAGGFFGGSVVEVHHLTKACHQAMVEDQANGIEAVWHDESHLNKYLLYHKPTKVLSPEYVWDQKLLGWPSIMKKLRYVAVPKNHQAIRN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38649-1", "uniprot_id": "BGAT_MOUSE", "id": "P38649-1", "name": "Histo-blood group ABO system transferase", "aln": "----MNLR-GRPKCNFLHLGILPFAVFVLVFFGYLFLSFRSQNLGHPG----------------AVTRNAYLQPRVLKPTRKDVLVLTPWLAPIIWEGTFNIDILNEQFRIRNTTIGLTVFAIKKYVVFLKLFLETAEQHFMVGHKVIYYVFTDRPADVPQVILGAGRQLVVLTVRNYTRWQDVSMHRMEMISHFSERRFLREVDYLVCADADMKFSDHVGVEILSTFFGTLHPGFYSSSREAFTYERRPQSQAYIPWDRGDFYYGGAFFGGSVLEVYHLTKACHEAMMEDKANGIEPVWHDESYLNKYLLYHKPTKVLSPEYLWDQQLLGWPSIMKKLRYVAVPKDHQAIRN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16442-1", "uniprot_id": "BGAT_HUMAN", "id": "P16442-1", "name": "Histo-blood group ABO system transferase", "aln": "MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDHLQRVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** *: ** : ::***:* : ** : :: * .* **.**.* *.****.*******:*****:** *****:::**********:****.**********:******:* ******:*: **:* **:**:* ** ** *.*******:***:**.*.*:** ******* *.**:* ********:.:********* * **:*******:****** *.***** *.****** ** :**:***:**: *:*****.******:****** ***********:***:*****::::***:.****:***:** ", "identical_positions": 225, "similar_positions": 61, "identity": "63.56%" }, { "cls_id": "homologset.agr.MGI:2135752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LDP4-1", "uniprot_id": "A0ABK0LDP4_RAT", "id": "A0ABK0LDP4-1", "name": "E3 ubiquitin-protein ligase", "aln": "---------------MSFVLSR--MAACGGSCKNKVTVSKPVWDFLSKETPARLARLREEHRVS--ILIDGETSDIYVLQLSPQGPPPAPPNGLY------LARKALKGLLKEAEKELKKAQ----RQGELMGCLALGG-GGEHPELHRPGPPPLRAAPLLPPGARG-------LPPPPPPLPPPLPPRLREDAEEQETTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80V91-1", "uniprot_id": "DTX3_MOUSE", "id": "Q80V91-1", "name": "E3 ubiquitin-protein ligase DTX3", "aln": "---------------MSFVLSR--MAACGGSCKNKVTVSKPVWDFLSKETPARLARLREEHRVS--ILIDGETSDIYVLQLSPQGPPPAPPNGLY------LARKALKGLLKEAEKELKKAQ----RQGELMGCLALGG-GGEHPELHRPGPPPLRAAPLLPPGARG-------LPPPPPPLPPPLPPRLREDAEEQETTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9I9-1", "uniprot_id": "DTX3_HUMAN", "id": "Q8N9I9-1", "name": "E3 ubiquitin-protein ligase DTX3", "aln": "---------------MSFVLSR--MAACGGTCKNKVTVSKPVWDFLSKETPARLARLREEHRVS--ILIDGETSDIYVLQLSPQGPPPAPPNGLY------LARKALKGLLKEAEKELKKAQ----RQGELMGCLALGG-GGEHPEMHRAGPPPLRAAPLLPPGARG-------LPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QUJ1-1", "uniprot_id": "F1QUJ1_DANRE", "id": "F1QUJ1-1", "name": "E3 ubiquitin-protein ligase", "aln": "MQRSSVDFFIEWKQAFSSCISSDEMSVRAGQGSDEVLVSQAVWDYLAAAGRPWLVDFEDKQGLSADIIRRGERGGCCAVRLSPVEGSSRARTGMMESLVSPVTRKAFIDLCRCARKEMTKQEAAPKRKRSLLPCVAAMEPDGERSLLPPPPPQPRRSQRQQQKYRKSADMDTCVVLPMQQEASARTVSELVVCHEEESTVCSICMGEMVEKTTLDKCGHAFCRSCLEQAFQVKKACPVCRLVYGQLIGNQPANGSMMVERDPDLELPGHEGYGCICIIYSFPPGLQAQEHPNPGVRYPGTDRVAYLPDNPEGNRVLRMLRRAFEQRLIFTIGTSMTTGMHNVITWNDIHHKTSIWGGPRCFGYPDPTYLVRVTEELREKGITAD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* *:. .* .::* **:.***:*: . *. :.::: :* *: ** .. .::*** .. . .*: ::***: .* : *.**:.* : *: .*: *:* .**:. : . * * *: :. : * .. ..* **:.:.*.**:**: : .**:** *:**..*: :*:*******:* .****:**** ** *:*.:*. * **.:* ** * * * ****:*. ************ ******* ****:** ::*:**:*** ********** ************* ***: *********.** **** **** *", "identical_positions": 167, "similar_positions": 91, "identity": "43.49%" }, { "cls_id": "homologset.agr.MGI:2135755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91W29-1", "uniprot_id": "COX42_MOUSE", "id": "Q91W29-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MFSRAARSLVMRTG-LRTRGT----GTHSPGDAAGS-QRRMTPY-VDCYAQR-SYPMPDEPFCTELSEEQRALKEKEKGSWTQLSQAEKVALYRLQFHETFAEMNHRSN-EWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLAAHWDYEKKEWKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y94-1", "uniprot_id": "COX42_RAT", "id": "Q91Y94-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MFSRATRSLVMKTGGLRTQG------THSPGSAASSSQRRMTPY-VDCYAQR-SYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSN-EWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KJ9-1", "uniprot_id": "COX42_HUMAN", "id": "Q96KJ9-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MLPRAAWSLVLRKGGGGRRG------MHSSEGTTRG-GGKMSPY-TNCYAQR-YYPMPEEPFCTELNAEEQALKEKEKGSWTQLTHAEKVALYRLQFNETFAEMNRRSN-EWKTVMGCVFFFIGFAALVIWWQRVYVFPPKPITLTDERKAQQLQRMLDMKVNPVQGLASRWDYEKKQWKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R6I1-1", "uniprot_id": "F1R6I1_DANRE", "id": "F1R6I1-1", "name": "Cytochrome c oxidase subunit 4", "aln": "---MLSSRALVRGLQSGFWRRLS------TSSGIWAAHTHDVDVTDCSVPQYNNRLDTPLPDVPFVRNLSAEQKKLKEKEKGPWTQLSKEEKLAIYRLTHELSFPEMRKGSK-EWMTVLAGVFFFLGFTGLLVWWQRVFVYGDVPHTLSQEWIEKQTQRMLDMKVNPITGFAHKWDYEKKQWK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00425-1", "uniprot_id": "COX5B_YEAST", "id": "P00425-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "------------MLRTSLTKG---------ARLTGTRFVQTKALSKATLTDLPER-WENMPN----LEQKEIADNLTERQKLPWKTLNNEEIKAAWYISYGEWGPRRPVHGKGDVAFITKGVFLGLGISFGLFGLVRLLANPETPKTMNREWQLKSDEYLKSKNANPWGG------YSQVQSK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00424-1", "uniprot_id": "COX5A_YEAST", "id": "P00424-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "------------MLRNTFTRAGG------LSRITSVRFAQTHALSNAAVMDLQSR-WENMPS----TEQQDIVSKLSERQKLPWAQLTEPEKQAVWYISYGEWGPRRPVLNKGDSSFIAKGVAAGLLFSVGLFAVVR-MAGGQDAKTMNKEWQLKSDEYLKSKNANPWGG------YSQVQSK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VIQ8-1", "uniprot_id": "Q9VIQ8_DROME", "id": "Q9VIQ8-1", "name": "Cytochrome c oxidase subunit 4", "aln": "MALRLLNSAVLRQLASQLPKSAQVGSVAAVHTLDKIGKREIVGYGWNGTACYADRVDYPLPAVR-FREPTNEINALRAKEQGDWKKLSTQEIKALYRASFCQTIAEVQAGSG-EWKLHLGVSLLFCAAAIWVAVLMNIFVYDELPVTFDEEHQKAQLQRIIDLEINPVTGLTSKWDYENKKWKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .* :* : * ::: * *. * * : . .. . : : : . . *: * . : : . : ** * *.: : * ", "identical_positions": 14, "similar_positions": 28, "identity": "7.61%" }, { "cls_id": "homologset.agr.MGI:2135756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPX0-1", "uniprot_id": "HSPB8_RAT", "id": "Q9EPX0-1", "name": "Heat shock protein beta-8", "aln": "MADGQLPFPCSYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTAPWPEWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRNPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSPFGESSFNNELPQDNQEVTCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK92-1", "uniprot_id": "HSPB8_MOUSE", "id": "Q9JK92-1", "name": "Heat shock protein beta-8", "aln": "MADGQLPFPCSYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTAPWPEWALPRLSSAWPGTLRSGMVPRGPPATARFGVPAEGRSPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPATVFASLSPEGLLIIEAPQVPPYSPFGESSFNNELPQDNQEVTCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJY1-1", "uniprot_id": "HSPB8_HUMAN", "id": "Q9UJY1-1", "name": "Heat shock protein beta-8", "aln": "MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:**.* ***********************************.**:***********************.************.****************************************************************.***********************.*************.*****:", "identical_positions": 185, "similar_positions": 10, "identity": "94.39%" }, { "cls_id": "homologset.agr.MGI:2135760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1QK11-1", "uniprot_id": "F1QK11_DANRE", "id": "F1QK11-1", "name": "", "aln": "MASDVLHRFICLCRYLQDPCHVARFQKLCGVRGTFAKKAAENDDKLSVNGACAGQRQGAREASGDS----------ADRLPGQRLRKSLNVKQDECAHNGPADTDPKG-TVKPLRRNSLTGDVGQEFIIENKFLFYLFTIGTELGNEMFFIVFFPFLMWNVDPYVSRQLIVVWAWVLFLGQSTKDVVRWTRPASPPVVKVEV--FYNSEYSMPSTHAMSGTALPFSLFLLTCSRWEYPFMFGLSI---ALFWSILVCISRIYMGMHSVLEVITGFLYSVLILAVLHPMLDDIDTFYL-SHSYAPLVVLLVHVGFSLVAFSLDTWSTSRGDTAQALATAAGAALACRLNHQLGLLPDPPEEALPLALPLIDEALLTRSVMRMLMGVAVLLAVRAAMKVVAIPLACKIFGVPSDDVRKARQ------------HAQVELAYRFLVYGTVAYCCVCLVPLLFGLLGLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PZN9-1", "uniprot_id": "A0A8M1PZN9_DANRE", "id": "A0A8M1PZN9-1", "name": "", "aln": "MAGGIKAGFVRLLHYLQDPQHVARFQRLCGVRGSDTRDSVRNGVQGTRSGDVHNGGGDATRRRKAG----------AETDTEKRNNGLANGTAGENVNGDNNGHDALGSAVKPSRRNSLTGDAGQEFLIENKFLFYLFTLGTELGNELFYISFFPFFMWNVDAYVSRRLVVVWVWVMYLGQCTKDVFRWPRPASPPVVKVEM--FYNSEYSMPSTHAMSGTAIPLSLFLLTYGRWEYPMLLGLSL---AISWCVLVCLSRIYMGMHSILDIIAGFLYSLLILVVFSPALDIIDTFNR-THPYAPLMIISLHVGLGLFSFTLDTWSTSRGDTAQILGSGAGIALASHVNYHLGLLPDPPASAFPLQPPSFTLSLVALCLLRFFLGVLILLATRAVMKALTIPLVCWVFGIPSNDVRKARQ------------HMEVELPYRYIVYGTVGLNALFLVPFLFAHVGLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JI99-1", "uniprot_id": "SGPP1_MOUSE", "id": "Q9JI99-1", "name": "Sphingosine-1-phosphate phosphatase 1", "aln": "MS--LGQRLALLASRLQEPQRVASFQRLCGVEVPLSSPAADEDAETEVRGAPGEPRRRGRQPGAED-----------SPAKADCCGAPNGVRNGLAAEPGPTGPRRAG----SQRRNSLTGEEGELVKVSNLPLYYLFCLGTELGNELFYILFFPFWIWNLDPFVGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPVIKLEV--FYNSEYSMPSTHAMSGTAIPIAMFLLTYGRWQYPLIYGLIL---IPCWSSLVCLSRIYMGMHSILDVIAGFLYTILILIIFYPLVDLIDNFNQ-TYKYAPLIIIGLHLILGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHAAYTLGLSLEPSLHMLPLAIPPLTVTLFGKAILRIVLGMLLVLFVRDIMKKITIPLACKLSSIPCHDIRQARQ------------HMEVELPYRYITYGMVGFSITFLVPYVFSFIGIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99P55-1", "uniprot_id": "SGPP1_RAT", "id": "Q99P55-1", "name": "Sphingosine-1-phosphate phosphatase 1", "aln": "MS--LGQRLALLAIRLQEPQRVASFQRLCGVEVPLGSPKAGEDAETEVRGAPGDPRRRPRQSGADG-----------SPAKPDCCGAPNGVRNGLAAEPGPTGPRRAG----SLRRNSLTGEEGELAKVSNLPLYYLFCFGTELGNELFYIIFFPFWIWNLDPFVGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPVIKLEI--FYNSEYSMPSTHAMSGTAIPIAMILLTYGRWQYPLIYGLIL---IPCWSSLVCLSRIYMGMHSILDVIAGFLYTILILIIFYPLVDLIDNFNQ-TYKYAPLIIIGLHLILGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHAAYNLGISLDPSLHTLPLAIPPLTVTLFGKAILRVVIGMLLVLFVRDIMKKVTIPLACKLFGIPCHDLRQARQ------------HMEVELPYRYITYGTVGFSITFLIPYIFSFIGIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BX95-1", "uniprot_id": "SGPP1_HUMAN", "id": "Q9BX95-1", "name": "Sphingosine-1-phosphate phosphatase 1", "aln": "MS--LRQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAG----ALRRNSLTGEEGQLARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEV--FYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLIL---IPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQ-THKYAPFIIIGLHLALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVTLFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQ------------HMEVELPYRYITYGMVGFSITFFVPYIFFFIGIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23501-1", "uniprot_id": "DS1P2_YEAST", "id": "P23501-1", "name": "Dihydrosphingosine 1-phosphate phosphatase YSR3", "aln": "-----------------------------MTIIQTVTELGVTEDTIKVQMAPSGGKHLLADPGNHP----------AEHFESQMSWLRFQTRQYLTRFTDNQSDFVHS----------------LQKKHRTPFRDVYFKYTSLMGSHMFYVIVLPMPVWLGYRDLTRDMIYVLGYSIYLSGYLKDYWCLPRPKSPPVDRITLSEYTTKEYGAPSSHSANATAVSLLFFWRICLSDTLVWPTKLLLLSLVIFYYLTLVFGRVYCGMHGMLDLFSGAAVGAICFFIRIWVVHALRNFQIGEHLWFPLLSVAWGLFILFNHVRPIDECPCFEDSVAFIGVVSGLDCSDWLTERYGWNLVCSRYASCGSKVFLR-PLVGVASVIVWKDVISKTAVYTLLIKLLRFHDDRSEKVHFHNETSEEE-----ECLLYSGVSKVEIVGRFLIYAGIPTTVFLLCPVFFTWTNLR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47013-1", "uniprot_id": "DS1P1_YEAST", "id": "P47013-1", "name": "Dihydrosphingosine 1-phosphate phosphatase LCB3", "aln": "-----------------------------MVDGLNTSNIRKRARTLSNPNDFQEPNYLLD-PGNHP----------SDHFRTRMSKFRFNIREKLLVFTNNQSFTLSR----------------WQKKYRSAFNDLYFTYTSLMGSHTFYVLCLPMPVWFGYFETTKDMVYILGYSIYLSGFFKDYWCLPRPRAPPLHRITLSEYTTKEYGAPSSHTANATGVSLLFLYNIWRMQESSVMVQLLLSCVVLFYYMTLVFGRIYCGMHGILDLVSGGLIGIVCFIVRMYFKYRFPGLRIEEHWWFPLFSVGWGLLLLFKHVKPVDECPCFQDSVAFMGVVSGIECCDWLGKVFGVTLVYNLEPNCGWRLTLARLLVGLPCVVIWKYVISKPMIYTLLIKVFHLKDDRNVAARKRLEATHKEGASKYECPLYIGEPKIDILGRFIIYAGVPFTVVMCSPVLFSLLNIA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . * : :*.. *:: :*: :* : :: : ::*. ** .** :**: :: : : ..**. **:*: ..*.:.: :. * : : : :.*:* ***.:*::.:* : : : : : : : *:. : : : : . ... *:. :. :* * : *. : . : : : .: :::: *:: *. : * .* .: ", "identical_positions": 35, "similar_positions": 94, "identity": "7.53%" }, { "cls_id": "homologset.agr.MGI:2135796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKP8-1", "uniprot_id": "CHRC1_MOUSE", "id": "Q9JKP8-1", "name": "Chromatin accessibility complex protein 1", "aln": "---------------------------------------------------------------------------MADAAVGK-EKCGDQRLVSLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQYLATCSYRHGSG-KAKKA--------LTYSDLASTAEDSET--LQFLADILPKKILASKYLKMLKE-----------------------KREE-EEDNEDDGSDLGEALA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LIV5-1", "uniprot_id": "A0ABK0LIV5_RAT", "id": "A0ABK0LIV5-1", "name": "Chromatin accessibility complex protein 1", "aln": "MPASSSKAAFERAGLCSSGLPEVLRRLKALLPGDCRSVSEGFFLGAVSQAFRPPRYTESAQARPRGASRAARTRKMADSVVGK-DKCGEQRLVSLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQYLATCSYRHGSG-KAKKA--------LTYSDLASAAEDSET--LQFLADILPKKILASKYLKMLKE-----------------------KREE-EDD-DDDGSDLGEVPA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRG0-1", "uniprot_id": "CHRC1_HUMAN", "id": "Q9NRG0-1", "name": "Chromatin accessibility complex protein 1", "aln": "---------------------------------------------------------------------------MADVVVGK-DKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQCLATYSYRHGSG-KEKKV--------LTYSDLANTAQQSET--FQFLADILPKKILASKYLKMLKEE----------------------KREEDEENDNDNESDHDEADS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V452-1", "uniprot_id": "CHRC_DROME", "id": "Q9V452-1", "name": "Chromatin accessibility complex 16kD protein", "aln": "---------------------------------------------------------------------------MGEPRSQPPVERPPTAETFLPLSRVRTIMKSSMDTGLITNEVLFLMTKCTELFVRHLAGAAYTEEFGQRPGEA--------LKYEHLSQVVNKNKN--LEFLLQIVPQKIRVHQFQEMLRLN----------------------RSAGSDDDDDDDDDDDEEESESESESDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40366-1", "uniprot_id": "DLS1_YEAST", "id": "P40366-1", "name": "Protein DLS1", "aln": "---------------------------------------------------------------------------MNNETSGKETASAPLCSPKLPVEKVQRIAKNDPEYMDTSDDAFVATAFATEFFVQVLTHESLHRQQQQQQQQVPPLPDELTLSYDDISAAIVHSSDGHLQFLNDVIPTTKNLRLLVEENRVRYTTSVMPPNEVYSAYVVNDTAPKPNIVEIDLDNDEDDDEDVTDQE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : **:.::: * *.. : .::.:. : .**:**: *: : . : :. *.*..:: . ... ::** :::* . : : : : : ::: .* : ", "identical_positions": 16, "similar_positions": 50, "identity": "6.48%" }, { "cls_id": "homologset.agr.MGI:2135874", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQV8-1", "uniprot_id": "CBPN_RAT", "id": "Q9EQV8-1", "name": "Carboxypeptidase N catalytic chain", "aln": "MPDLPSAFLPLLLLSKFVTPVTFRHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGTHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNTSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKYGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRSPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCNKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLTGAVISVTGINHDVTSGEHGDYFRLLLPGTYSVTAKASGYEPKTVTVTVGPAGPTLVDFQLKRSTTQVHPVQKAPGRGQGSRAKQPRTSRKKDQAAKR-HRGPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJN5-1", "uniprot_id": "CBPN_MOUSE", "id": "Q9JJN5-1", "name": "Carboxypeptidase N catalytic chain", "aln": "MPDLPSAFLPLLLLSKFVTPVTFRHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNNLTGAVISVTGINHDVTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTVGPAGPTVVDFQLKRSSSQVYPVQRAPGRGQGGRAKQPRTSRKKDPATKR-HRGPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15169-1", "uniprot_id": "CBPN_HUMAN", "id": "P15169-1", "name": "Carboxypeptidase N catalytic chain", "aln": "MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.** *.** **** *:*:*******************:*:**.***:*.*****:**:********:** ******************.*****:******************::*************************** .************************:***.* *************************:*::*:*******:**************:***.*. :**:.:*****:***.************.*********************************************:*** :********************************* ***:.*****:*********:*********** *:*:*.*.**:*:********* **:*:*:**** .** **::**.* :* *** :***: :: :****", "identical_positions": 376, "similar_positions": 59, "identity": "82.1%" }, { "cls_id": "homologset.agr.MGI:2135882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQQ4-1", "uniprot_id": "GPR45_MOUSE", "id": "Q9EQQ4-1", "name": "Protein carrier GPR45", "aln": "-MACNSTPMGTYEHLLLNVSNTLDPGDTPLSAPLRISLAIMMLLMIVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAITLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKMIIAASWVLSFCISAPSFTGWTFMEVPARAPQCVLGYTEFPAERAYVVTLVVAVFFAPFGVMLCSYLCILNTVRKNAVRVHNQSD--SLDLRQLTGAGLRRLRRQQQQASLDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSAFSRRFYYSASFYTTSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPHTFQILPKVPERIQRKIQPSTIYVCN-ENQSAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A8X5-1", "uniprot_id": "D4A8X5_RAT", "id": "D4A8X5-1", "name": "", "aln": "-MACNSTPIGTYQHLLLNASNTLDPGATPLSAPLRISLAIMMLLMIVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAITLVTVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAASWVLSFCISAPSFTGWTFMEVPARAPQCVLGYTEFPAERAYVVTLVVAVFFAPFGVMLCSYLCILNTVRKNAVRVHNQSD--SLDLRHLSGAGLRRLRRQQQQASLDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSAFSRRFYYSASFYTTSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIQRKIQPSTVYVCN-ENQSTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5Y3-1", "uniprot_id": "GPR45_HUMAN", "id": "Q9Y5Y3-1", "name": "Probable G protein-coupled receptor 45", "aln": "-MACNSTSLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSD--SLDLRQLTRAGLRRLQRQQQ-VSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIRRRIQPSTVYVCN-ENQSAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S7I8-1", "uniprot_id": "B0S7I8_DANRE", "id": "B0S7I8-1", "name": "", "aln": "MFACNGSSLEACGLLEPTETEMQEADTALMPTTLRVALAAIMIFMITIGFLGNGIVCLIVYQKPAMRSAINLLLATLAFSDIMLSLLCMPFTAVTLATTDWSFGMGFCRVSVMLYWLFVLEGVSILLIISVDRFLIIVQRQDKLTPHRAKILIGASWALSLCVSLPSLVGWRTAGIGAQVPQCILGYSESLADRGYTVLLAVAVFFVPFGVMLYSYLCILNTVRRNALRIHNHTSEGSVAISHVSKLGLTGLQRPQV--NIDMSFKTRAFTTILILFIGFSVCWLPHTVVSLLSVFSRRFYLSPAFYPVSIGALWLSYLKAVFNPVIYCWRIRKFREACLEFMPKTFHLCPKIPGRSRRRIRPSNIYVCSSETQSSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***.:.: : * . :: :.. : :.:.**::** :*::* .:***** :**:****:*********************** ******:** *. * ** ***:*. ***:******:********************.*:***::*..**.**:*:: **:.** : *:.***:***:* *:*.*.* *.*****.****** :*:*******:**:*:**::. *: : ::: ** *:* * .:*:****:*********:***:*****:* ****.**:*** ..:**..* .*******:****::*****:******:*::*:**:: **:* * :*:*:**.:***. *.**:*", "identical_positions": 222, "similar_positions": 103, "identity": "58.89%" }, { "cls_id": "homologset.agr.MGI:2135884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQQ3-1", "uniprot_id": "GPR63_MOUSE", "id": "Q9EQQ3-1", "name": "Probable G protein-coupled receptor 63", "aln": "MVVSGVLTAPAVLTAPHSGTSNTTFVVFENSHVNITAPLPFQHPSAGPLLRYSLETMTSPGFSSLAVNSTAVTPAPAVFKSLNLAVQIILSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRLSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATAFSVAFPLAVGNPDLQIPSRAPQCVFGYTTNSGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPRLPGHTRRRIRPSAVYVCGEHRTVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZJ6-1", "uniprot_id": "GPR63_HUMAN", "id": "Q9BZJ6-1", "name": "Probable G protein-coupled receptor 63", "aln": "MVFS------AVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FF58-1", "uniprot_id": "E7FF58_DANRE", "id": "E7FF58-1", "name": "", "aln": "MLYS------STSPPVDSGQPNP------------SARPASQPVGARAMENSSTKLNSSPDFRTLSEYITPSSVWQEPVEGLNLPLQVFLGLVIICVLLLAFLGNMVVCVMVYQRAAMRSAINILLASLAFADMMLAVLNMPFALVTMVTTHWIFGDVFCRVSAMFFWMFVMEGVAILMIISVDRFLIIVQKQDKLSPRSAKLLIAVSWSLSFCFSFPLSFGYPALYIPPRAPQCVFGYTAERGDHAYVMLIMLLFFFVPFLVMLYTFMGILSTLRHNALRIHSHPDSVCLSQASKLGLMSLQRPFQMNIDMSFKTRAFTTILILFSVFTACWAPFATYSLLSTFSRTFYYRQNFFQISTWLLWICYLKSALNPLIYYWRIKKFRDACLDLMPKYFKFLPQLPGHTKRRIRPSAVYVCGEHRSVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NQR8-1", "uniprot_id": "NDUF4_RAT", "id": "Q9NQR8-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4", "aln": "----------------------------------------MGARMTRAFRNFNVEKRAEQEISKRKP------------------------------------------SMAPKHPSTRSLLQEHLS--QYPEIEEEVSRKDNKLLSLLRD------------------------------------VYVNSKDPVPSLPVKAIEPQQQPKEFRLPIGDQFDKNIKDIPKGK---------------------------------ITVVEALTLLNNHKLSPETWTA------------------EKIAQEYHLELEDVNSLLKYFVTFEVKIVPPEDRKAIQSK--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . : : : . *. ::.: ** :: *: :.:: * . *:::: : *: :* : . .* : . . . * ..: .. ** :.: *. *.:: * .: . :: : :: . ..::* * .* . .* . : : ", "identical_positions": 19, "similar_positions": 66, "identity": "4.47%" }, { "cls_id": "homologset.agr.MGI:2135885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TCT4-1", "uniprot_id": "ENTP7_MOUSE", "id": "Q3TCT4-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 7", "aln": "MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFIPCVLLLLLIMDLRHWATSLPRDRQYERYLARVGDLEATNTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVK------KIKPGISAMADTPEHAS-DYLRPLLSFAAAHVPVKKHRETPLYILCTAGMRLLPERQQLAILADLVKDLPLEFDFLFSQS--QAEVISGKQEGVYAWIGINFVLGRFDHEDESDSDTSVDSAAGRRRTVGILDMGGASLQIAYEVPTSASDLPPKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGLTDMVKRNNQVLHFRGKGDWASCRTLLSPLLAR---SNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRIGGHYHGPTFAKAAQDYCGMAWPVLAQRFKNGLFSSHADEHRLKYQCFKSAWMYEVLHEGFHFP---------YDYPNLQTAQLVYDREVQWTLGAILYKTR------------FLPLRDLRQGQGGVRPAHGSWLR--------LSFVYNHYLFFACTLVVLLAIVLYLLRIHR-------IHRRQTRASAPLDLLWIEQVVPMIGVQVGP---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZNB5-1", "uniprot_id": "D3ZNB5_RAT", "id": "D3ZNB5-1", "name": "nucleoside-triphosphate phosphatase", "aln": "MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFIPCLLLLLLIMDLRHWTTSLPRDRQYERYLARVGDLEATNTEDPNLSYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVK------KIKPGISAMADTPEHAS-DYLRPLLSFAAAHVPVKKHRETPLYILCTAGMRLLPERQQVAILADLVKDLPLEFDFLFSQS--QAEVISGKQEGVYAWIGINFVLGRFDHEDESDADTSVDSASGRRRTVGILDMGGASLQIAYEVPTSASVLPPKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQRTGLSPDNPFLDPCLPVGLTDVVERNSQVLHFRGKGDWATCRTMLSPLLAR---SNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMTWSVLAQRFKNGLFSSHADEHRLKYQCFKSAWMYEVLHEGFHFP---------YDYPNLQTAQLVYDREVQWTLGAILYKTR------------FLPLRDLRQ--GGVRQAHGSWFR--------LSFVYNHYLFFACTLVVLLAIVLYLLRIHR-------IHRRQTRASAPLDLLWIEQVVPMIGVQVGP---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQZ7-1", "uniprot_id": "ENTP7_HUMAN", "id": "Q9NQZ7-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 7", "aln": "MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSASLPRDRQYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVK------KIKPGISAMADTPEHAS-DYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFLFSQS--QAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLAR---SNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQVLHEGFHFP---------YDYPNLRTAQLVYDREVQWTLGAILYKTR------------FLPLRDLRQ--EGVRQAHGSWFR--------LSFVYNHYLFFACILVVLLAIFLYLLRLRR-------IHHRQTRASAPLDLLWLEEVVPMMGVQVGP---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40009-1", "uniprot_id": "YND1_YEAST", "id": "P40009-1", "name": "Golgi apyrase", "aln": "--------------------------------------------------------------------------MLIENTNDRFGIVIDAGSSGSRIHVFKWQDTESLLHATNQDSQSILQSVPHIHQEKDWTFKLNPGLSSFEKKPQDAYKSHIKPLLDFAKNIIPESHWSSCPVFIQATAGMRLLPQDIQSSILDGLCQGLKHPAEFLVEDCSAQIQVIDGETEGLYGWLGLNYLYGHFNDYN---------PEVSDHFTFGFMDMGGASTQIAFAPHDSG-EIARHRDDIATIFLRSVNG------DLQKWDVFVSTWLGFGANQARRRYLAQLIN-TLPENTNDYENDDFSTRN-LNDPCMPRGSSTDFEFKDTIFHIAGSGNYEQCTKSIYPLLLKNMPCDDEPCLFNGVHAPRIDFANDKFIGTSEYWYTANDVFKLGGEYNFDKFSKSLREFCNSNWTQILANSDKGVYN-SIPENFLKDACFKGNWVLNILHEGFDMPRIDVDAENVNDRPLFQSVEKVEERELSWTLGRILLYASGSILAGNDDFMVGIAPSERRTKLTGKKFIPGKLLESDQLRKQSSSLSNKGFLMWFAIICCIFYLIFHRSHIIRRRFSGLYNITKDFKTGIRRRLKFLRRSDPFSRLEEGELGTDVDGFKDVYRMKSSSMFDLGKSSATMQREHEPQRTASQSANLAPSNLRPAFSMADFSKFKDSRLYD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.* :*:*:*.*******.*: * :. * : .* :. : : *::**:*:: ..*:.* .:::***.** :* .: . *::* .********: * :** .* :.* :**..:. * :**.*: **:*.*:*:*:: *:*:. : . : *.*::****** ***: * :. :::: *.*:* ..* : : *:*:*:****.* **:** ::* ** :* :. .:*. * : ***:* * : .: :. ::*. * *:: * : *** : .: . . :**:: . *** *.:* * **::* ::**:::**.*: .*:*: :::*. *. : . .:*::. *: ** ***. *: ::*****.:* * * :::.: * :**:.**** ** : :. : * * : *. :. *: : :*:: . : :: :.:: :: * :: ::. * ::.. *: :: * ", "identical_positions": 157, "similar_positions": 189, "identity": "21.72%" }, { "cls_id": "homologset.agr.MGI:2135916", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM59-1", "uniprot_id": "KCIP2_RAT", "id": "Q9JM59-1", "name": "A-type potassium channel modulatory protein KCNIP2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MRGQGRKESLSESRDLDGSYDQLTGHPP-GPSKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRPLD----------------PDSVEDEFELSTVCHRPEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQG-DSSNYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLSWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMR------------SMQLFDNVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ69-1", "uniprot_id": "KCIP2_MOUSE", "id": "Q9JJ69-1", "name": "A-type potassium channel modulatory protein KCNIP2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MRGQGRKESLSDSRDLDGSYDQLTGHPP-GPSKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRPLD----------------PDSVEDEFELSTVCHRPEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQG-DSSNYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMR------------SMQLFDNVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS61-1", "uniprot_id": "KCIP2_HUMAN", "id": "Q9NS61-1", "name": "A-type potassium channel modulatory protein KCNIP2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MRGQGRKESLSDSRDLDGSYDQLTGHPP-GPTKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRLLD----------------PDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQG-DSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMR------------SMQLFDNVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RTI3-1", "uniprot_id": "A0A8M1RTI3_DANRE", "id": "A0A8M1RTI3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MKVKSRDESFNTSGECDGSNDLLTGNPPSGQRKKNMKQRFLKLLPCCHVDSTPAVRQ----------------------------------NSIEEDFELATVCYRPDSLDKLMELTKFTKTELQILYRSFKNDCPTGVVNEETFQLIYSHFFPHG-DSSAYAHFLFEAFDRRKNGAVNFEDFVVGLSIILRGTVTDRLSWAFSLYDLNKDGCITKEEMNDIMKSIYDMMGKNTCPCINDSAPREHVESFFQKMDRNNDGVITMEEFLESCQKDEAIME------------SMQMLDHVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBL2-1", "uniprot_id": "Q9VBL2_DROME", "id": "Q9VBL2-1", "name": "EF-hand domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASPP-ES-------------PIEEVVY-------------------------------------------ELEHTRVP-KPIPVALEDLCRQTKFTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKFFPHG-NSSLYAHYVFKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILAIHELMGRRPHQPEDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTR------------SLQMFDNDLXXQEGE-LEPGLRNS--------------------RTIISLIDL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IR92-1", "uniprot_id": "Q8IR92_DROME", "id": "Q8IR92-1", "name": "EF-hand domain-containing protein", "aln": "MAGPQVQHSQRPNSAYYTGLNGGSGSGGGGGGGGAGGGGAGGGSSAGMSSSASHTGLHALRQVSNETELIYRGSHSNGTVNELPSSAQHHLLTGRAVQQHQQQQQMHHQTVSSIAGTGSSVTDALISTINSGGGGGGPSGSSCSTAALGIKKSSTQRSIEIIVDASQCGKELVASGP-GSGAAGSGAAIVSTLDVEDVEQGGGGQESSSSHRKSSRHRHRPLHRRLITYLRNLFQGSTTQNDSELEEFETPARYRPDSLSALSRATRFTEDEIKRIYRGFKAECPTGVVKEDTFKVIYSQFFPQGANPTLYAHYVFNTLDQDHSGIVSFEDFVQGLSILSRGSVEEKLRWTFSLYDINGDGFITREEMTDIVTAIYELMGRLPDECPEEEKIKGKVEQIFQKMDTNRDGVVTLEEFLEACRNDDAISRSMSYTVPRRRRHQLSAQQQHLQHQKHQQQEPEKRKSNHKTKNKQQQKQQQPHSTRHQNCCHIIDMDGDSTTSTTTASAATGTTLNCNVLYDYGAAEEDDDDQDEDDEDSDEEYRSFVCRHCQRSQSVVQQPRSNRRSQSQSKSRKRSKSRKRHQSKQGHHQGQQGHQGHHGQQLTRWPEINVANEQAIRFRCPQVGPQVGRDLHTPQPMHFHHPQSQSQKAKSKSRPRKHRACPPASLSKAGAAAAAAAPGPPAPPAPPADPSQLPPSEQHPLAPLNVIVGGAEVEVDPQQPQPPTTPDSPSLVTVSTWYTVAKQGVSC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : . * .*. * . *:**. *:: :**.** :** *:*:*: *: **::***:* :.: ** ::*:::* .* :.*.*:: ** : **:: ::* *:*.***:* ** *:: *: :*: :*:::**: . : : :*: .*:*:* *.**::*:***:*:* :*: : . .:. :: : ", "identical_positions": 64, "similar_positions": 77, "identity": "8.57%" }, { "cls_id": "homologset.agr.MGI:2135932", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TA76-1", "uniprot_id": "LCE3A_HUMAN", "id": "Q5TA76-1", "name": "Late cornified envelope protein 3A", "aln": "MSCQQNQQQCQ-----PPPKC----PAKSPAQCLPPASSSCAPSSGGCG-PSSERSCCLSHHRCRRSHRCRCQSSNSCDRGSGQQGGSSSCGHSSAGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TA77-1", "uniprot_id": "LCE3B_HUMAN", "id": "Q5TA77-1", "name": "Late cornified envelope protein 3B", "aln": "MSCQQNQQQCQPLPKCPSPKC----PPKSSAQCLPPASSCCAPRPGCCGGPSSEGGCCLSHHRCCRSHRCRRQSSNSCDRGSGQQDGASDCGYGSGGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYE3-1", "uniprot_id": "LCE3D_HUMAN", "id": "Q9BYE3-1", "name": "Late cornified envelope protein 3D", "aln": "MSCQQNQQQCQPPPKCPSPKC----PPKSPVQCLPPASSGCAPSSGGCG-PSSEGGCFLNHHR--RHHRCRRQRPNSCDRGSGQQGGGSGCGHGSGGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5T5B0-1", "uniprot_id": "LCE3E_HUMAN", "id": "Q5T5B0-1", "name": "Late cornified envelope protein 3E", "aln": "MSCQQNQKQCQPPPKCPSPKC----PPKNPVQCLPPASSGCAPSSGGCG-PSSEGGCFLNHHR--RHHRCRRQRSNSCDRGSGQQGGGSGCCHGSGGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5T5A8-1", "uniprot_id": "LCE3C_HUMAN", "id": "Q5T5A8-1", "name": "Late cornified envelope protein 3C", "aln": "MSCQQNQQQCQPPPSCPSPKC----PPKSPAQCLPPPSSDCALSSGGCG-PSSESGCCLSHHRHFRSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0KWJ1-1", "uniprot_id": "A0ABK0KWJ1_RAT", "id": "A0ABK0KWJ1-1", "name": "", "aln": "MSCQQSQKQCQPPPKCPSPKCSPKCPPKSTAQCLPAASSCCATSSGGCSVPSSEGGCCLSHHR-RRSHRCRRRSSSSCDRGSGQQSGGSGCGHSSGGCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A8R6-1", "uniprot_id": "A0A8I6A8R6_RAT", "id": "A0A8I6A8R6-1", "name": "", "aln": "MSCQQSQKQCQPPPKCPSPKCSPKCPPKSTAQCLPAASSCCATSSGGCSVPSSEGGCCLSHHR-RRSHRCRRRSSSSCDCGSGQQSGGSSCGHSSGGCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V05-1", "uniprot_id": "Q91V05_MOUSE", "id": "Q91V05-1", "name": "", "aln": "MSCQQSQKQCQPPPKCPSPKCSPKCPPKSTAQCLPAASSCCATSSGGCSLPSSEGGCCLSHHR-RRSHRCRRRSSSSCDRGSGQQSGGSGCGHSSGGCC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*:*** *.*** *.*...****..** ** .* *. **** .* *.*** * *:** : ..*** *****.*.* :.*.***", "identical_positions": 52, "similar_positions": 22, "identity": "52.53%" }, { "cls_id": "homologset.agr.MGI:2135937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z335-1", "uniprot_id": "SBK1_RAT", "id": "Q9Z335-1", "name": "Serine/threonine-protein kinase SBK1", "aln": "------------------------------------------MSVGCPEPEPLHSLPCCGPGAAPV-PGAGVP-LLTED----MQALTLRTLAASDVTKHYELVRELGKGTYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFETEECYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHSRQLVHRDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSG-TIPYTAPEVCQAGRADGFAVDTGVDVWAFGVLIFCVLTGNFPWEAASGA-DAFFEEFVRWQRGRLP----GLPSQWRRFTEPALRMFQRLLALEPERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRLP----------------------------GPLRLEAPGPLKRTVLTESGSGSRPSPPSVGPV-----VPVPVPVPVPVPEAGLAPPAPPGRT---------------------------------------------------------DGRADKSKGQVVLATAIEICV----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZX0-1", "uniprot_id": "SBK1_MOUSE", "id": "Q8QZX0-1", "name": "Serine/threonine-protein kinase SBK1", "aln": "------------------------------------------MSVGCPEPEPLHSLPCCGPGAAPV-PGAGVP-LLTED----MQALTLRTLAASDVTKHYELVRELGKGTYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFETEECYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHSRQLVHRDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSG-TIPYTAPEVCQAGRADGFAVDTGVDVWAFGVLIFCVLTGNFPWEAASGA-DAFFEEFVRWQRGRLP----GLPSQWRRFTEPALRMFQRLLALEPERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRLP----------------------------GSLRLEAPGPLKRTVLTESGSGSRPSPPSVGPV-----VPVPVPVPVPVPEAGLAPPAPPGRT---------------------------------------------------------DGRTDKSKGQVVLATAIEICV----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q52WX2-1", "uniprot_id": "SBK1_HUMAN", "id": "Q52WX2-1", "name": "Serine/threonine-protein kinase SBK1", "aln": "------------------------------------------MSVGCPEPEPPRSLTCCGPGTAPG-PGAGVP-LLTED----MQALTLRTLAASDVTKHYELVRELGKGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFETEDCYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQLVHRDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSG-TIPYTAPEVCQAGRADGLAVDTGVDVWAFGVLIFCVLTGNFPWEAASGA-DAFFEEFVRWQRGRLP----GLPSQWRRFTEPALRMFQRLLALEPERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRPPA--------------------------AGPLRLEAPGPLKRTVLTESGSGSRPAPPAVGSVPLPVPVPVPVPVPVPVPEPGLAPQGPPGRT---------------------------------------------------------DGRADKSKGQVVLATAIEICV----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F802-1", "uniprot_id": "E7F802_DANRE", "id": "E7F802-1", "name": "Serine/threonine-protein kinase SBK1", "aln": "--------------------------------------------MQEHEGERQQGAGSAQVGVPPAGRGVGMGGAPVED----MQALSITSLSASEVEQQFELISPLGKGTYGKVDLVVHRTQGTKLALKYVSKNKTKLRSFLREYSLNAALGCSPFIIKVLNVLFETEDSYVFGQEYAPAGDLFDIIPPQAGLPEEMVKRCVQQLGLALDFMHSKSLVHRDVKPENVLLFDRECRRVKLADLGMTRRSGSRIKRISG-TIPYTAAEVCQASVSEGIIVATTQDVWAFGVLLFCMLTGNFPWEAALPN-DAFFAEFQRWQRGAFPP--GSVPSQWRRFSDDALRMFGRLLALEPERRCGVKEVFYFLKYDLLNHHRRRASCRTSRG------------------------------------------GATHCSAHRHAD----PSPPSGTSCLR----PTPLKRSILSELHSSREESSKSPS---------------------------------------------------------PNRQDKSK--VMMTTPIEICV----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAH6-1", "uniprot_id": "A1ZAH6_DROME", "id": "A1ZAH6-1", "name": "Protein kinase domain-containing protein", "aln": "-----------------------------------------------------------------------MSKKPRGN----IHKIREFELEKIQLVDEFDIIQIVGEGWFGKILLVEHRGSQTEMVLKAVPKPYVTLRDFYREFHYGLHLGVHRHIVTTYDVAFETAGFYVFTQEYAPLGDLTSNVT-DSGVGEVYSKRVAKQLASAIDYMHSKDIVHRDIKLDNVLIYRSDFQRIKLCDFGESFPTGSTVERRNE-WLPYSPPEVLEIKPEGSYKADPSHDVWQFGIVIFVCLTGCLPWQKAASD-DPRYVRYLAWQGGLMMMPLRRTPRLFKLLTSNAQRMFKRFFARISNRPKSLADVTKFLDDRWLAKTAQKEMAEYETDELCPSMYSFHSSPDEKNKLLYTLADCGIETNVDRQQKKNRIKDWIESSIITEEDEEENEETNSASPSSSVSREPLPGHISSLRKPTSPAESAKEINSTLKDATQKHFDPRTGALQQGPSEMGQVAMAYSKSASPASNYSTTASTLNNADSLMTLGSRQDLLASNLTMYTSMETELNRLGEADPRLNQRTQSNNPLLTTFDVNTNPAAKNSIGVGTRGSSRSILKSSIATAAYPALGAFNHGQSHSLQQLNQHLQTSTGLTPSKSSFFRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM90-1", "uniprot_id": "SBKH_DROME", "id": "Q9VM90-1", "name": "Serine/threonine-protein kinase meng-po", "aln": "MGTIEKRSFSFRLRRSFGDGGSTNSRNSNNNSSTCTNHNNQKRCSTPLTPTSTSTGRLEVPGAASVSRRSSIYKKPDKNDGGQIHLIPDVELPLMTFADQYNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYELSHHHHILSAYAVAFQTMDYYVFAMEHAPYGDLASNIG-PNGLHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKLCDFGATTKKGLLVHKVKHTWTSCVPPEQLELIKNERFQCLPVSDSWQFGILLYNILTGNPPWQSADWVKDQSYANFMKYEQRKTT----KVPDNFRRFSPRLMRCFRKYLSHDPEDRCKITEVAKYMKDRWVECRISTSKSATLISPTNHDQ---------------------------------------DSCIYLNQREGRLSGDENKLRFKR---MMSTYGLDIPIDQAMVRRRVWDWLS----------------------------------------------------------TCDANFDPDVESLHALDLLQ----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : * . ..::: :.:* :.*: * :: * :.** * ..::.* :* *. .*:.. * *:* *** *:** *** . : *: * * :**. *:.:**.:.:****:* :*:*:: : *:**.*:* : * :.: . . ..* : . * * **:::: *** **: * * : .: :: * :: :: * * : :: .: :* ::. . . . : : .:: ", "identical_positions": 61, "similar_positions": 96, "identity": "9.31%" }, { "cls_id": "homologset.agr.MGI:2135945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924P3-1", "uniprot_id": "LCN8_MOUSE", "id": "Q924P3-1", "name": "Epididymal-specific lipocalin-8", "aln": "--MEARLLSNVCGFFLVFLLQAESTRVELVPEKIAGFWKEVAVASDQKLVLKAQRRVEGLFLTFSGGNVTVKAVYNSSGSCVTESSLGSERDTVGEFAFPGNREIHVLDTDYERYTILKLTLLWQGRNFHVLKYFTRSLENEDEPGFWLFREMTADQGLYMLARHGRCAELLKEGLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B3EY82-1", "uniprot_id": "B3EY82_RAT", "id": "B3EY82-1", "name": "", "aln": "--MEARLLVVVCRLVLEFLLQAESTRVELVPEKIAGFWKEVAVASDQNLVLKAQRRVEGLFLTFSGRNVTVKAVYNSSGSCMTERSVGSERDAAGEFAFPGNREIHVMDTDYERYTILKLSVLWQGTNFHVLKYFTRSLENEDEPGFWRFREMTADQGLYMLARHGRCAELLKEGLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6JVE9-1", "uniprot_id": "LCN8_HUMAN", "id": "Q6JVE9-1", "name": "Epididymal-specific lipocalin-8", "aln": "MPGAAEALPTVTVTLVAGAVPPASG--ALTAHCIGGFWREVGVASDQSLVLTAPKRVEGLFLTLSGSNLTVKVAYNSSGSCEIEKIVGSEIDSTGKFAFPGHREIHVLDTDYEGYAILRVSLMWRGRNFRVLKYFTRSLEDKDRLGFWKFRELTADTGLYLAARPGRCAELLKEELI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * * .: : . * *... *.***:**.*****.***.* :********:** *:***..******* * :*** *:.*:*****:*****:***** *:**:::::*:* **:**********::*. *** ***:*** ***: ** ********* *:", "identical_positions": 104, "similar_positions": 38, "identity": "58.76%" }, { "cls_id": "homologset.agr.MGI:2135946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2VLH6-1", "uniprot_id": "C163A_MOUSE", "id": "Q2VLH6-1", "name": "Scavenger receptor cysteine-rich type 1 protein M130", "aln": "MGGHRMVLLGGAGSPGCKR-FVHLGFFVVAVSSLLSASAVTNAPGEMKKELRLAGGENNCSGRVELKIHDKWGTVCSNGWSMNEVSVVCQQLGCPTSIKALGWANSSAGSGYIWMDKVSCTGNESALWDCKHDGWGKHN-CTHEKDAGVTCSDGSNLEMRLVNSAGHRCLGRVEIKFQGKWGTVCDDNFSKDHASVICKQLGCGSAISFSGSAKLGAGSGPIWLDDLACNGNESALWDCKHRGWGKHNCDHAEDVGVICLEGADLSLRLVDGVSRCSGRLEVRFQGEWGTVCDDNWDLRDASVVCKQLGCPTAISAIGRVNASEGSGQIWLDNISCEGHEATLWECKHQEWGKHYCHHREDAGVTCSDGADLELRLVGGGSRCAGIVEVEIQKLTGKMCSRGWTLADADVVCRQLGCGSALQTQAKIYSKTG--ATNTWLFPGSCNGNETTFWQCKNWQWGGLSCDNFEEAKVTCSGHREPRLVGGEIPCSGRVEVKHGDVWGSVCDFDLSLEAASVVCRELQCGTVVSILGGAHFGEGSGQIWGEEFQCSGDESHLSLCSVAPPLDRTCTHSRDVSVVCSRYIDIRLAGGESSCEGRVELKTLGAWGPLCSSHWDMEDAHVLCQQLKCGVAQSIPEGAHFGKGAGQVWSHMFHCTGTEEHIGDCLMTALGAPTCSEGQVASVICSGNQSQTLLPCSSLSPVQTTSSTIPKESEVPCIASGQLRLVGGGGRCAGRVEVYHEGSWGTVCDDNWDMTDANVVCKQLDCGVAINATGSAYFGEGAGAIWLDEVICTGKESHIWQCHSHGWGRHNCRHKEDAGVICSEFMSLRLTNEAHKENCTGRLEVFYNGTWGSIGSSNMSPTTVGVVCRQLGCADNGTVKPIPSDKTPSRPMWVDRVQCPKGVDTLWQCPSSPWKQRQASPSSQESWIICDNKIRLQEGHTDCSGRVEIWHKGSWGTVCDDSWDLNDAKVVCKQLGCGQAVKALKEAAFGPGTGPIWLNEIKCRGNESSLWDCPAKPWSHSDCGHKEDASIQC----LPKMTSESHHG--TGHPTLTALLVCGAILLVLLIVFLLWTLKRRQIQRLTVSSRGEVLIHQVQYQEMDS--KADDLDLLKSSGVIQRHTEKENDNL-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JVY2-1", "uniprot_id": "A0A0G2JVY2_RAT", "id": "A0A0G2JVY2-1", "name": "Scavenger receptor cysteine-rich type 1 protein M130", "aln": "MGKNRMVLLGGAGSPGYKG-FVHLGFFVVAVSSLLSVSAVTQAPEGRKKELRLAGGENNCSGRVELKIHEKWGTVCGNGWSMNEVSVVCQQLGCPTLIKAPGWANASAGSGDIWMDKVSCTGNESALWDCKHEGWGKHN-CTHEQDAGVTCADGSNLEMRLVNSGDNRCSGRVEIKFQGKWGTVCDDNFSKDHASVICKQLGCGSAISFSGSAKLGAGSGQIWLDDLACNGNESAIWDCKHRGWGRHNCDHAEDVGVICLDGADLSLRLVDGVSKCSGRLEVRFQGEWGTVCDDSWDRRDASVVCKQLGCPTAITAIGRVNASEGSGPIWLDSISCEGHEPALWECKHQEWGKHYCNHKEDAGVTCSDGADLELRLVGGGSRCAGMVEVEIQKLTGKVCSRGWTLTDADVVCRQLGCGSALQTQSKIYSKTKTEATNTWLFPGSCSGNETSLWQCKNWQWGGLSCDHFEEAQVTCSGHRKPRLVGGEIPCSGRVEVKHGDTWGSVCDFDLSLEAAGVVCRELQCGTVVSILGGAHFGEGSGQIWGEEFQCSGDESHLSLCSVAPPLDRTCSHSRDVSIVCSRYIDIRLADGKSSCEGRVELKTLGAWGPLCSSHWDIEDAHVLCQQLKCGVALSTPGGAHFGKGAGQVWRHKFHCTGTEEHIGDCPMTALGTPMCSDGQVASVICSGNQSHTLLPCSSSSSVQTTSSTIAKDSDVPCIASGQLRLVGGGGRCAGRVEVYHEGSWGTICDDSWDLTDANVVCKQLDCGVAINATGSAYFGEGTGDIWLDEIDCSGKESHIWQCHSHGWGRHNCRHKEDAGVVCSEFMSLRLTNEAHRVNCTGRLEVFYNGTWGSIGSSNMSPTTVGVVCRQLGCADNGTVKPTSSDKTPTRPMWTDSVQCPKGVDTLWQCPSSPWKQRQASPS-QESWIVCDDKIRLQEGHTDCSGRVEIWHRGSWGTVCDDSWDLNDAEVACKQLGCGQAVEALKEAAFGPGTGPIWLNEMKCRGNESSLWDCPARPWSHSDCGHKEDASVKC----LPRMTLESQHG--TGHSTLTALLVCGAILLVLLIAFLLWTLKRRQTQRLTVSSRGEVLIHQVQYQEMDS--KTDDLDLLKSSENSNDSYDFNADGLTSLSKYLPISGIKRGPIIHNPLRLAFKKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VB7-1", "uniprot_id": "C163A_HUMAN", "id": "Q86VB7-1", "name": "Scavenger receptor cysteine-rich type 1 protein M130", "aln": "MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTR-GGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAIWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQ--ATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNS-SSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPS-EETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSENSHESADFSAAELISVSKFLPISGMEKEAILSHTEKENGNL-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ***** .:**.. : **:*. *.::* ***.. **.: .*****..***:******:*::::*****.*****: ***:*:****** *** ****:***** ****:*** ***********:*****. ***::******:*********.. ..: * **:******:*********. *******:** ****:*****:::* *** **:*** *******:*:***:***:********.**** .************:.***************:***.** **:*.*********::********:* * ****.:**:***.::*:***:*******:*.**********:****** ******** ******:* **:*.*** * :**************:*. ::*** ******* .**.****::*:*********:**::***::***.**:******:*************.***:** *:*****.*:*********************.****.*****.*.*******.*** : **:*****.:***** :***..*::.**************.**.****:*************** * * **:**** **:* * *******:*:*** :****:. *.. ************:** .*.* *.: .* .**.::* *.** *******.**********:********:***.**::**:***:**.** ********:****:* *****: *.****:**********::**********:**********.** : *:*********:**::*.*.** **************:*.::* . **: : ***.* ****** ***********::* **** :*:** **:******* *.********* *************:**:*.*:***** *::*:*** ** *********:**:***********: *.**:*******:::* : : . :: * : :.:: *: : *.:**.:::.::: * **** ***:****** *:**:**:**:* ::*****::** : : . * ", "identical_positions": 789, "similar_positions": 227, "identity": "67.9%" }, { "cls_id": "homologset.agr.MGI:2135947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIQ8-1", "uniprot_id": "D3ZIQ8_RAT", "id": "D3ZIQ8-1", "name": "", "aln": "MSSGITMSEPRLNWDVTPKNGLKVFFSPENYKDHSMAPSLKELYILSNRRIGENVSVSANSVENEPAVSSATQAKEKV----GMILLPKPRVPYPRFSRFSQREQRTFVDLLVKYAKIPSSSKTVGTNTNEFLQYLDMKKHVNEEVNEFLKFLQNSAKKCAQDYNMLSDEARLFTEQILRACIEQVKKYPEFYTLHEVTSLMGFFPFKIEMGLKLEKTLLVLGSAKFVKTAFPSMPVKLQLSKEDMSSIENPQQQAEAMHCDISKDPNAEKLVSRYHPQIALTSQALFTLLNNHGPSYKEQWEIPVCVQMIAVEGSKPVKVIYINSPLPRKQMTMRERNQIFHEVPLKHIFSKTTSVPVSAVFMDKPEEYTSEVDISTEASECRKIETLENLDLDFDGDVTELETFGVTTTSPSRSPSSESDSSAPIMTDVHTAPKVTAIPVAPAAPVTPAAPVAPVVAPVAPVVAPVAPAAPVTPVTPEASAIPNITDDSRSLCQILMKQLQKEKQLFSGVESGPEACKNKDDQGLEPCAEEGPSANAKSLTQDSEVHRTEEISNESD------------VGALCTSDERQSVQKNADNPNETATASETADTEKGIPCGSDTDEDCLIIDTESKSNSDGRTAGLGS-------SPNSS-AQASVENQTTTTVS-EESCVLKKPIKRVYKKFDPVGEILKMQDELLKPVSRTIPELPLTNSEESKQPSASEQPSATLDASTWPKSSWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRVETRPRSKKRKKIRRQFPVYVLPKVEYQGCYGVEALTESELCRFWTESLLHSNCSFYVGHIDAFTSKLFMLEEITSEELKEKLAALKISSLFNILQHILKKLCSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKAHCDLPGVPSSLSVPWVPLDPSYLLPYHIHHGRIPCTFPPKSLRPAAQPKVGATRMPTRNHRNPVSRETKSSCLPVQQVENEGVAQNKRKIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UZ18-1", "uniprot_id": "ICE2_MOUSE", "id": "Q3UZ18-1", "name": "Little elongation complex subunit 2", "aln": "MSSSITMSEPRLNWDVTPKNGLKAFFSPENYKDHSMAPSLKELYILSNRRIGENLSVSASSVENEPAVSSATQAKEKV----GMILLPKPRVPYPRFSRFSQREQRTYVDLLAKYAKLPSSSKTVGTNTNEYLQYLDMKKHVNEEVNEFLKFLQNSAKKCAQDYNMLSDEARLFTEQLLRACIEQVKKYPEFYTLHEVTSLMGFFPFKTEMGLKLEKTLLVLGSAKFVKTAFPSMPVKLQLSKEDMSSIETPQQKAEVMHCDISKDPNAEKLVSRYHPQIALTSQALFTLLNNHGPSYKEQWEIPVCVEMIAVEGSKPVKVIYINSPLPRKQMTMRERNQIFHEVPLKHIISKNTSVPVSAVFMDKPEEYTSEVDMPTEAGECRKIETLENLDMDFDGDVTELETFGVTTTSPPRSPSSESDSSAPLMTDVHAVPKIAAVPLAPATPVAPTMPVAP--------ATPVTPTMPMAPATPEASATPNITDDSRSLCQILMKQLQKEKQLFSGVEGGPEGCKNKDDQGLEPCGEEVPSANAKSLTQDNEVHRTEGISKESD------------VGVLCTNDERQGGQGNANNPNNTATASEAAESEKGIPCGSDTDEDCLIIDTESRS-CDGKTADLGS-------RPNSS-AQASAGNQATTTVS-EESCVLKKPIKRVYKKFDPVGEILKMQDELLKPVSRKVPELPLTNSEESKQPPASEQPSAALDAAPWPKSSWPSAFQKPKGRLPYELQDYVEDTSEYIAPQEGNFVYKLFSLQDLLLLVRCSIQRVETRPRSKKRKKIRRQFPVYVLPKVEYQGCYGVEALTESELCRFWTESLLHSNCSFYVGHIDAFTSKLFMLEEIASEELKEKLAALKISSLFNILQHILKKLCSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKAHCDLPGVPSSLSVPWVPLDPSYLLPYHIHHGRVPCTFPPKPLRPAAQAKVGGTRMPTRNHRNPVSMETKSSCLPVQQVENEGVARNKRKIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q659A1-1", "uniprot_id": "ICE2_HUMAN", "id": "Q659A1-1", "name": "Little elongation complex subunit 2", "aln": "MSSKMVISEPGLNWDISPKNGLKTFFSRENYKDHSMAPSLKELRVLSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTIGMVLLPKPRVPYPRFSRFSQREQRSYVDLLVKYAKIPANSKAVGINKNDYLQYLDMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEKILRACIEQVKKYSEFYTLHEVTSLMGFFPFRVEMGLKLEKTLLALGSVKYVKTVFPSMPIKLQLSKDDIATIETSEQTAEAMHYDISKDPNAEKLVSRYHPQIALTSQSLFTLLNNHGPTYKEQWEIPVCIQVIPVAGSKPVKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEFISEMDMSCEVNECRKIESLENLYLDFDDDVTELETFGVTTTKVSKSPSPASTSTVPNMTDAPTAPKAGTTTVAPSA--------------------------------------PDISANSRSLSQILMEQLQKEKQLVTGMDGGPEECKNKDDQGFESCEKVSNSD--KPLIQDSDLKTSDALQLENSQEIETSNKNDMTIDILHADGERPNVLENLDNSKEKTVGSEAAKTEDTVLCSSDTDEECLIIDTECKNNSDGKTAVVGSNLSSRPASPNSSSGQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKVPELPLMNLENSKQPSVSEQLSGPSDSSSWPKSGWPSAFQKPKGRLPYELQDYVEDTSEYLAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISNLFNILQHILKKLSSLQEGSYLLSHAAEDSSLLIYKASDGKVTRTAYNLYKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLDTTTQQKIGGTRMPTRSHRNPVSMETKSSCLPAQQVETEGVAPHKRKIT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :.:*** ****::******.*** *************** :*********:..**.****************** **:*********************::****.****:*:.**:** *.*::**************.**********************:******::***********.*****************: ***********.***.*:***.*****:******:*:::**..:* **.** ************************:**********:**********:::*.* ***************:*:****************.::**.***************: **:*:. *..******:**** :***.*************. .:***. * *:.* ***. :.** : .:**:: *:*: :****.****:********.:*::.*** ********:*.* : * *.* **.::: :: :. *.. :. * :..** . * :*.::.:..**:*.:*. : *.*****:*******.:. .**:** :** **** .***. **:.*: * *********************************:**.:***** * *:****..*** *.. *::.****.**************************:************************:**:***************************.**************:*********.***************:****:********:*****.************.**********************:************:*:**.****************** **********:*******.* .::* *:*.******.****** ********.****.**** :**** ", "identical_positions": 732, "similar_positions": 170, "identity": "71.62%" }, { "cls_id": "homologset.agr.MGI:2135951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MS3-1", "uniprot_id": "MP17L_MOUSE", "id": "Q99MS3-1", "name": "Mpv17-like protein", "aln": "---------------------------------------------------------------MASWWRAFPQAAR--------RYPWPTNVLLYAGLFSAGDALQQRLRGG-----------------------------------------------PADWRQTRR----------------VATLAVTFHGNFNYVWLRLLE-----RALPGRAPRTVLAKVLCDQTVGGPIALSAFYVGMS-VLQGK--DDIFLDLKQKFWNTYKSGLMYWPFVQLTNFSLVPVHWRTAYTGLCAFLWATFLCFSQ-QSGDGTLQSIFIFLRRK--EASDKSPEK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GL80-1", "uniprot_id": "A0A8I6GL80_RAT", "id": "A0A8I6GL80-1", "name": "", "aln": "---------------------------------------------------------------MANWWRAFPRAAR--------RYPWPTNVLLYAGLFSAGDALQQRLRGG-----------------------------------------------PADWRQTRR----------------VATLALTFHGNFNYMWLRLLE-----RALPGRAPRTVLAKVLCDQTVGGPVALSAFYVGMS-ILQGK--DDIFLDLRQKFWNTYK----------LTNFSLVPVNWRTAYTGLCGFLWATFLCFSQ-QSGDGTVESIFILLRRK--EAGDRSPEK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2QL34-1", "uniprot_id": "MP17L_HUMAN", "id": "Q2QL34-1", "name": "Mpv17-like protein", "aln": "---------------------------------------------------------------MAGWWPALSRAAR--------RHPWPTNVLLYGSLVSAGDALQQRLQGR-----------------------------------------------EANWRQTRR----------------VATLVVTFHANFNYVWLRLLE-----RALPGRAPHALLAKLLCDQVVGAPIAVSAFYVGMS-ILQGK--DDIFLDLKQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFICFSQ-QSGDGTFKSAFTILYTKGTSATEGYPKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IUD3-1", "uniprot_id": "A0A0R4IUD3_DANRE", "id": "A0A0R4IUD3-1", "name": "", "aln": "---------------------------------------------------------------MRKSFFKRLKRAK--------ILPWISNVTLYGCLFAGGDFVHQCIAQRD----------------------------------------------EMDWRHTRN----------------VAIVALSFQGNFNYFWLRALE-----SRFPGRSAGMVFRKLVLDQSFASPLATSVFYTGVS-FLEGK--EDIFEDWREKFFNTYKTGLMYWPFMQFLNFVLMPLYLRTAFMGCSAFVWATFLCFSR-QSGDGTAAVALAWVMAPKKRLLHRSTDEEK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W588-1", "uniprot_id": "Q9W588_DROME", "id": "Q9W588-1", "name": "Mpv17-like protein", "aln": "---------------------------------------------------------------MVPAAVKLLQASLGQWRRGSKLHPMAKGALTYAVMWPAGSLIQQAMEGRK-L-------------------------------------------REYDWARALR----------------FSLFGALYVAPTLYGWVRLTS-----AMWPQTNLRTGIVKAITEQLSYGPFACVSFFMGMS-LLELKTFSQAVEETKEKAAPTYKVGVCIWPILQTINFSLVPEHNRVVFVSICSLMWTIFLAYMK---THHEEQSNSAVLPCT-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VN75-1", "uniprot_id": "Q9VN75_DROME", "id": "Q9VN75-1", "name": "", "aln": "---------------------------------------------------------------MFRSLVNITSK-----------YKVLRGMISYGTLWPCGSLIEQTMIEKKTF-------------------------------------------RTYDWMKCLR----------------FSLFGFFFMGPTIYVWIRLAS-----VMWPRTDIKSSLCKAITEQTAYDPMAISSFLFFMT-LMEGNSYAEAKREVSDKFLDAYKVGVIYWPCVQTVNFAFVPARNQVVFTSFFSMCWTTFLAYVKFLQLHPPVDVDHHALDIHFLEM---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JNT1-1", "uniprot_id": "A8JNT1_DROME", "id": "A8JNT1-1", "name": "Mpv17-like protein", "aln": "---------------------------------------------------------------MARLISGVRNLFH--------RYPFVTNSAIYGSLYVGAEYSQQFASKRWLATASKP--------------------------------------EDIDYATIGR----------------YAVMGTAVYAPTLYLWYKWLD-----RAFPGTTKVIIVKKLVLDQFVLTPYLLTVFYAGMS-IMEGS--ADIFLELREKFVPTFMRSCIFWLPAQALNFSLVAPRFRVIYMGICGLIWVNILCWTK--RQSLPVATKEIATDSNNNAAAIRNSET--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06563-1", "uniprot_id": "SYM1_YEAST", "id": "Q06563-1", "name": "Protein SYM1", "aln": "----------------------------------------------------------------MKLLHLYEASLK--------RRPKTTNAIMTGALFGIGDVSAQLLFPTSKVN------------------------------------------KGYDYKRTAR----------------AVIYGSLIFSFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAFAPLGLPFYFTCMS-IMEGRSFDVAKLKIKEQWWPTLLTNWAVWPLFQAINFSVVPLQHRLLAVNVVAIFWNTYLSYKN----SKVMEKDKVPVHYPPVVE---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08743-1", "uniprot_id": "YO292_YEAST", "id": "Q08743-1", "name": "Vacuolar membrane protein YOR292C", "aln": "MPLQLFGRDQIVVHYDNGNMSNDDQNHQSVLGSWTRRAAAALRTLMNKRIQRITLTHWLLLVIWVTSLWKFTSHYRQLYANSAVFATLCTNILLFGISDILAQSIACFYSYHVDPIPQILNDTFHHVQNNRDVENGGGYESDELSIFNDFTSEHSSYTDNDDYPELDRPLATFKTDTFDFFRWGCFMFWGFFISFFQAPWYKFLN----FFYTEDPTVVQVFERVLSDQLLYSPISLYCFFMFSNYVMEGGDKDTLGKKIQRLYISTLGCNYLVWPMVQFINFLIMPRDFQAPFSSSVGVVWNCFLSMRN--------ASK--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. :: . . * : . . : :* * : . .:: . : ** .:. : . .. * :. . ", "identical_positions": 6, "similar_positions": 30, "identity": "1.76%" }, { "cls_id": "homologset.agr.MGI:2135954", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q969G9-1", "uniprot_id": "NKD1_HUMAN", "id": "Q969G9-1", "name": "Protein naked cuticle homolog 1", "aln": "-------------MGKLHSKPAAVCKRRE--------------SPEGDSFAVS----AAWARKGIEEWIGRQR--CPGGVSGPRQLRLAGTIGRSTRELVGDVLRDTLSEEEEDDFRLEVALP---------------PEKTDGLGSGDEKKMERVSEPCPG------SKKQLKFEELQCDVSMEEDSRQE---WTFTLYDFD-NNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKMLRVKLTVAPDGSQSKRSVLVN-------------------------------------------------------------------------------------------------------------------------------------------------QADLQSARPRAETKPTEDLRSW-------------------------------------------------------------------------------------------------EKKQRAPLRFQGDSRLEQSGCYHHCVDEN---------IERRNHYLDLAG--------------------IENYTSQFGPGSPS-VAQKSELPPRTSNPTRSRSHEP------------EAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFVRSPKAQGKS---------VGVGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQ----------------------------------------------------------------------------------------------------------APLASGG-PVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99MH6-1", "uniprot_id": "NKD1_MOUSE", "id": "Q99MH6-1", "name": "Protein naked cuticle homolog 1", "aln": "-------------MGKLHSKPAAVCKRRE--------------SPEGDSFAVS----AAWARKGIEEWIGRQR--CPGSVSGPRQLRLAGTVGRGTRELVGDTSREALGEEDEDDFPLEVALP---------------PEKIDSLGSGDEKRMERLSEPGQA------SKKQLKFEELQCDVSVEEDSRQE---WTFTLYDFD-NNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKTLRVKLTVAPDGSQSKRSVLFN-------------------------------------------------------------------------------------------------------------------------------------------------HTDLQSTRPRADTKPAEELRGW-------------------------------------------------------------------------------------------------EKKQRAPLRFQGDSHLEQPDCYHHCVDEN---------IERRNHYLDLAG--------------------IENYTSQFGPGSPS-VAQKSELPPRISNPTRSRSHEP------------EAAHIPHRRPQGVDPGSFHLLDTPFAKASELQQRLRGTQDGSKHFVRSPKAQGKN---------MGMGHGARGARSKPPLVPTTHTVSPSAHLATSPALLPTLAPLGHKKHKHRAKESQASCRGLQ----------------------------------------------------------------------------------------------------------GPLAAGGSTVMGREQVRELPAVVVYESQAGQAVQRHEHHHHHEHHHHYHHFYQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TJA6-1", "uniprot_id": "NKD1_DANRE", "id": "Q2TJA6-1", "name": "Protein naked cuticle homolog 1", "aln": "-------------MGKLHSKHAAICKARE--------------SPEGDSFVVN----ACLARKGLDDWMVKQKYYCSSSRVDQRDCQQKNNCELSPRDPLDEGYAEGISDEH---YRLEVALP---------------PEKTDSC-SVEERMQGTEGSATVG------PHKQLQFEELECAVSVEEDNRQE---WTFTLYDFD-NNGKVTREDITSLLHTIYEVVDASVNHSPSSSKTLRVKLSVAPDSSQRWKNCTQT-------------------------------------------------------------------------------------------------------------------------------------------------NTDTPNPKHKGE-KCIEDSKTS-------------------------------------------------------------------------------------------------EKKSRAFLRRYHAEHHSQQGCQRHCVDEN---------LERRNHYLDLAG--------------------IENYTSRFGTAAPATEPAKPTHATRSSNQSRSRSQEP------------ENGQ--------VHPAHHRRSQTMSTDPPAILTRHT-------HALRSPKTHRTP---------PTQASAGRVMRRGAPPPPSVPNQTP-PHQSSGP----------YRRHKQRPKEALH-YRALG----------------------------------------------------------------------------------------------------------PSVTSGP--VLEKEHVRDLPSLVLYEGGLAQVVQRHEHHHHHEHHHHYHHFYQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVV9-1", "uniprot_id": "NKD_DROME", "id": "Q9VVV9-1", "name": "Protein naked cuticle", "aln": "MAGNIVKWWKHKILGGYKQFSVQECTTDSEELMYHQVRASSSCSAPPDLLLVSERDNNIQLRSPVVNIITTPPGNASGAGSKQQSHHQTNHHSSGRSHPGHTAHPQDVSSGGSHSKHLRISSTSNGKHGKYSNMQQQLPQDEDVVDAAATMQQQQHTGHAHSRHLHHHKEERIRLEEFTCDVSVEGGKSSQPLQFSFTFYDLDGHHGKITKDDIVGIVYTIYESIGKSVVVPHCGSKTINVRLTVSPEGKSKSQPVVPVPVAAGFSSSHASKLKKLPTGLAAMSKPLAGGGVGSGGASALTTSAGNRRQHRYRPRKLIKSDDEDDDSNSEKEKDAAHAPAADQPSGSGTKATGKSHHHQSQSARYHQKNNSRAEQCCTEQNTPDNGHNTYENMLNLKCCKPEVDQVDCPSHRQHHQSHPNHQMRQQDIYMKQATQRVKMLRRARKQKYQDHCLETRQRSLSVGNDSACPNRHLQLQQPPVGHPQPQSLNHKSASGSPPLGVGGGGDMMLDGVQLRQPRPHSLTPHQHQQQNQQQQQQQRKSAECWKSALNRNDLISIIRESMEKNRLCFQLNGKPQANVSPIRQPAAQQQPQQQQRQRCNTGSKIPTLITNHSPVAQQSPLSCSPPTAEPTTPSIPAAPPAIEVNGQQHHPTHPTHPSHHNHHEHPQPHIPIYHQQLAINPAVLAAQQTHNTAHNKLNLCGYDSFLHATICGGGAAAHSPPATPSNVATVQPIPKKSQKNLLQGYQRLEQSQQQQQQQRSSKDYKNYGNLIYAKLSEQLQQKDREQRRQRHKQQQHQMLQDQPKDASRSEQRPPTSNSSSAGSKIYGDAVECAHLLASEEEDLPPSPQLTSTPSKVVSTDTLIDLNDDVGEAVAEAVTEGGKQSLEAEESGQQVEVELDTSASSSMIHRYVHEHIHHHYHHFKEQQDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. . *. . *. * : *. *. : : : .... :. : . . . : :.. *.:: . *:. * : . .:::::**: * **:* .. .: ::**:**:* ::**:*::**..:::**** :. ** . .** :.*:*:*:*:... : :.* . : : : : .: : :: : : .: .. * : .::.* :*:.. ::* * :. .. *. *: . :. . : . . : ** * ..*. .. : .. . : .:: . . .* *: : ::::: :.: : .:: * : *. : : : . .. ::*: *.* *.*:**::. : ", "identical_positions": 60, "similar_positions": 166, "identity": "6.47%" }, { "cls_id": "homologset.agr.MGI:2135956", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64121-1", "uniprot_id": "PRLHR_RAT", "id": "Q64121-1", "name": "Prolactin-releasing peptide receptor", "aln": "---MTSLPPGTTGDPDLFSGPSPAGSTPANQSAEASESNVSATVPRAAAVTPFQSLQLVHQLKGLIVMLYSIVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCAACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLKLSAYAVLGIWALSAVLALP-----------------------------------------------AAVHTYHVELKPHDVR--------LCEEFWGSQERQRQIYAWGLLLGTYLLPLLAILLSYVRVSVKLRN--RVVPGSVTQSQADWDRARRRRTFCLLVVVVVVFALCWLPLHIFNLLRDLDPRAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKMLLSWPR---------------------------------------------------------------------------KIVPHGQNMTVSVVI-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VMN6-1", "uniprot_id": "PRLHR_MOUSE", "id": "Q6VMN6-1", "name": "Prolactin-releasing peptide receptor", "aln": "---MTSLSTETTGDPDLSSGLLPASSTPANQSAEASEGNLSATVPRAAAVTPFQSLQLVHQLKGLIVMLYSIVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCAACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIALDRYVVLVHPLRRRISLRLSAYAVLGIWALSAVLALP-----------------------------------------------AAVHTYHVELKPHDVS--------LCEEFWGSQERQRQIYAWGLLLGTYLLPLLAILLSYVRVSVKLRN--RVVPGSVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHIFNLLRDLDPRAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKMLLSWPR---------------------------------------------------------------------------KIVPHGQNMTVSVVI-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49683-1", "uniprot_id": "PRLHR_HUMAN", "id": "P49683-1", "name": "Prolactin-releasing peptide receptor", "aln": "---MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALP-----------------------------------------------AAVHTYHVELKPHDVR--------LCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRN--RVVPGCVTQSQADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPR---------------------------------------------------------------------------KIAPHGQNMTVSVVI-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW75-1", "uniprot_id": "Q9VW75_DROME", "id": "Q9VW75-1", "name": "", "aln": "MANLSWLSTITTTSSSISTSQLPLVSTTNWSLTSPGTTSAILADVAASDEDRSGGIIHNQFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGR-WAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPS-EQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCFNPSNNNIINITRGYNRSDRNTCGPRLHHGKGDGGMGGGSLDADDQDENGITQETCLPKEKLLIIPREPTYGNGTGAVSPILSGRGINAALVHGGDHQMHQLQPSHHQQVELTRRIRRRTDETDGDYLDSGDEQTVEVRFSETPFVSTDNTTGISILETSTSHCQDSDVMVELGEAIGAGGGAELGRRIN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. . ..: :. * :*. . :... . : *. .: : :: :: :**: *.*:*:.** *: *: * * ::.***::* ******:*:*. .**:* *:* * *.** .***** * * ::*:*.:***:**:***.*:::*:: *:.* . ::.**.:: : ::* :*.::* :.. .. *** * * *: *:::. ::**:: * :.** :****.: *. **. :. : : ** *::** :*:.:*.**.:.***:::.*:: *:* :: : : *. ::.* :****:*****:****::.**:*::::* .: . *:.:..::* ", "identical_positions": 116, "similar_positions": 148, "identity": "19.27%" }, { "cls_id": "homologset.agr.MGI:2135957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AEB2-1", "uniprot_id": "A0A8I6AEB2_RAT", "id": "A0A8I6AEB2-1", "name": "Calmodulin-binding transcription activator 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAVTRGTPGENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGME-----CLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNG------------LEEFSVEQLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRAL---------------------------------TLASISHSKPPEPPPLIAPLPPELPKAHTS-----------------------------------------------------------------------------------------------------------------------------------PSSSSSSSSS-GFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLASQAEPRP-----------------PVSLAVVVGSEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVNPDFPEAEGTHTPCPALEPAAALEPQAAARGLPPQSGASGRRG-------------------------------------NKFFIQDDDSGEELKGPGTVPPVPSPPPSS--------------------------------------------------------PSSPAALQPSGRATRGETLFGGSAGSTSELEPFSLSSFPDLMG-------------------------------ELITDEAPGVPAPSPQLSPVLNTITDFSPEWSYPEGGVKVLITGPWT-EAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDSQFRMSILERLEQMEKRMAEIAAAGQAPGQGPEAPPIQDEGQGPGFEARVVVLVESMIPRSTWRGPERLMHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEADPLNVDHFSCTPLMWACALGHLEAAVLLFCWNRQALSIPDSLGRLPLSVAHSRG-----------------------------------------HVRLARCLEELQRQELSVEHPLALSPQSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPP--APMLASEISME-TIPGQLSFGAPETPLLLMDYEATNSKESAPSPSGLPLAQDDRAAPEDADS-------PPAVDVIPVDMISLAKQIIEATPERIKREDFSELPEAGASPREHTGTVGLSETMSWLASYLENVD----------------------------HFPSSAFPSELPFERGRP----------AIPPAPSWAEFLSASTSG--KMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQE---VAAAVIQRCYRKYKQ-------FALYKKMTQAAILIQSKFRSYYEQKRFQQS-------------RRAAVLIQQHYRSYRRR--------PGPPHRPSGPLPSRNKGTFLTKKQDQAARKIMRFLRRCRHRMRELKQNQE----------LEGLPQPGLAT--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y50-1", "uniprot_id": "CMTA2_MOUSE", "id": "Q80Y50-1", "name": "Calmodulin-binding transcription activator 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTKDTT--EVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMEPVSWQCLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNG------------AEEFSVEQLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRAL---------------------------------ALASISHSKPPEPPPLIAPLPPELPKAHTS-----------------------------------------------------------------------------------------------------------------------------------PSSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQAEPRP-----------------PVSLAVVVGSEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVNPDFPEAEGTHTPCPALEPAAALEPQAAARGLAPQLGANGRRG-------------------------------------NKFFIQDDDSGEELKGPGTVPPVPSSPPSS--------------------------------------------------------PSSPTALPPSGRATRGEALFGGSAGSSSELEPFSLSSFPDLMG-------------------------------ELISDEAPGVPAPAPQLSPALNAITDFSPEWSYPEGGVKVLITGPWT-EAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDSQFRMSILERLEQMEKRMAEIAAAGQAPGQGPEAPPIQDEGQGPGFEARVVVLVESMIPRSTWRGPERLIHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFCWNRQALSIPDSLGRLPLSVAHSRG-----------------------------------------HVRLARCLEELQRQELSVEHPLALSPPSSSPDTGLSSASSPSELSDGTFSVTSAYSSAPDGSPPP--APPLASDISME-MIPGQLSCGAPETPLLLMDYEATNSKEPAPSPCGPPLAQDNGAAPEDADS-------PPAVDVIPVDMISLAKQIIDATPERIKREDFSEFPDAGASPREHTGTVGLSETMSWLASYLENVD----------------------------HFPSSAPPSELPFERGRL----------AIPPAPSWAEFLSASTSG--KMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQE---VAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQS-------------RRAAVLIQQHYRSYRRR--------PGPPHRPSGPLPARNKGTFLTKKQDQAARKIMRFLRRCRHRMRELKQNQE----------LEGLPQPGLAT--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94983-1", "uniprot_id": "CMTA2_HUMAN", "id": "O94983-1", "name": "Calmodulin-binding transcription activator 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTKDTT--EVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGME-----CLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNG------------TEEFSVEHLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRAL---------------------------------TLTSIPHAHPPEPPPLIAPLPPELPKAHTS-----------------------------------------------------------------------------------------------------------------------------------PSSSSSSSSS-GFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRP-----------------SMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRG-------------------------------------NCFFIQDDDSGEELKGHGAAPPIPSPPPSP--------------------------------------------------------PPSPAPLEPSSRVGRGEALFGGPVG-ASELEPFSLSSFPDLMG-------------------------------ELISDEAPSIPAPTPQLSPALSTITDFSPEWSYPEGGVKVLITGPWT-EAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQVPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNRQALSIPDSLGRLPLSVAHSRG-----------------------------------------HVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPP--APLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADS-------PQAVDVIPVDMISLAKQIIEATPERIKREDFVGLPEAGASMRERTGAVGLSETMSWLASYLENVD----------------------------HFPSSTPPSELPFERGRL----------AVPSAPSWAEFLSASTSG--KMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQE---VAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQS-------------RRAAVLIQQHYRSYRRR--------PGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQE----------LEGLPQPGLAT--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZU4-1", "uniprot_id": "B7YZU4_DROME", "id": "B7YZU4-1", "name": "", "aln": "MENVPDISTSASSSSTSNSTSTLKLQSQITSKNVLIRSQSSGKLSSNEAKSAKPAATTSTTTTLRAAKLKIGAMQQQKQQHQQQHQATSGGNIILLRGTRNENGQIIIQNKQDILSLLSEQQQQQQQEKSHSSTAITLNQLPTATTVARKTIVQGSSGAGSSSSSSSSTISIVANSNNKEASSNTILLQTPINASQLESVLKAQERSKQANATQTKMVERPFMLKHATRSLSSESNCDSKSPFVLQTLKRLEKSQSILVIRNSTASTAATNTSMATSPPNGNSLATSSILSVTRTTKAAKGVAGALHKLKAAAATTATSGGASSAGATSSTATTILRLGKSATTVAINGASKLEATTSTTTAVPVPATATTSNKLSNAVTSEQQQQQQQQSTTTQTNVPLGNDGEPIKLPDNLESLPRADSFPSQRHRWNTNEEIAAILISFDKHGEWQSKEVRTRPKSGSLLLYSRKKVRYRRDGYCWKKRKDGKTTREDHMKLKVQGTE-----CIYGCYVHSAILPTFHRRCYWLLQNPDIVLVHYLNVPYPDDNKMAVIAPSITLWGDKK---EWTKEELVSQLKPMLSTINSDDDSDSGNDIEISTAETVESIVCQLMEKQRLSRQAALVKQLDCGCGDGGCVDGKTCTHPVMRRSAAMLKSSVQEKRLGEPFNGNTPNVVVASKLYSRWAERPRQHVDNHGQFHNVTQQLPQESAIKFQIIPPQQQQQQDGNYQQQQYRGGSQMLAARSNLVMQQQQQHQQQQQYHQQQQQQQQQQQQHQQQQQHLSLQRFVASQGQNSVHLNQQHRLQIANTTITATASDPATTLAAAAAVAAASGATPVALNIMDTELIENQNHMTANKITNSGSSNSSSSNASKQLAGQTNNKLNVVNNNDPGNNNFMYNQQQQLNASSNSNNSSQQQQQQQQQHYYKLQQTTATPTSGQPPPLAQVQPHSLAQPPVEAMCMSPEHRSSSQPTPATSSAGSIPSSVSVSISVSTSTPTPAPTSISTPTSGTSSTSSSLQSIIDGNQQQQITTTSTAATCDNLMSANALSEQDSHTVNNQATEAPNRSQLQSQSQSLSLNQNGCATYSASSDNSSQISDESSSFGGNNQNSSNSSTSEEEPQVEALSFFNETLDLSQEDIQRTLIANMPYNTTAAGATAPSTTITTGNTKLELSQQETKEKPAMGTETATEIEDDETDDVFANLDAFDMLVEFPELDLDDKQALNNTALEQSSFLGESAPSQPRKVHNICDFSPEWSYTEGGVKVLVAGPWTSSNGGAYTVLFDAQPVPTQLVQEGVLRCYCPAHEAGFVTLQVACGGFLVSNSVMFEYKLSLLADAP---FDATSSNDCLYKFTLLNRLSTIDEKLQVKTEHELTTDN-------TALYLEPNFEEKLVAYCHKLIKHAWSMPSTAASWTVGLRGMTLLHLAAALGYAKLVGAMLNWRSENP-HIILETELDALSQDVYGFTPLAWACVRGHVECSLLLYKWNHNALKIKTQAQQTPLDLASMRGHKVLLAQMYRLEKERCRKPQLRGGLANLSMNMGVEAEAEEQHQSFSAFDLELQRKHDGVFLRPVAVHSNQSPPNGSSRYSKRSSIDSGINMDIRSKSGKPLARLHSNFESHDSYALGVDSPLDSLTGTNCLLSPLRKMDFALCEVSTGESSPVHDKDCDDNSTSATDVTIGNDLVLPDAVVGDSDAKVLTLAEHIIAAMPERIKN-EADEMMVLGSPLTEPLTSESSALTDSFMDPLLDSLPNTHFDSDFSFDFHDHSYRYHDVSTPCSSLSPASSGPLQSPASYSILGTDPSVSSPSPPPSTKQLTEFLHASSISSYPFEADFSKLTLTDTEQRELYEAAKCIQKAYRSYKGRQKLEEQNKERSAATVIQNYYRRYKQ-------YAYYRQMTNAALVIQHGYRSYRRNKRFKKSGLCLSSSSDHGSVSSNSQCLSSFYDHYKQDQQQLHELGSQPSTPKETSPSGPLKRTYSQSTQNQAARKIQQFMRQSRIKLQKERAEKEKLVHQRRAEYLQNLQFQGQQEMLVYHENNISAPSSGNTNASNNNNLHQIQSNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .:. : : . **.***. :*.:* *********: **:*:**.** * :***:.**::**.****:**:*** ********************* * *:*******:*:************************* :* . . :: .*:: :*::***:.*****: *: . ... *.: : : :* *. :.: .* .* :.. : ** . ::...*: : * : .:.: * *.. : :**: : : . ..*.**.*** . :: * :.. . ... *. :: . :* .. .... * : : . .** * . : **. . .* ..* . : .*. . ... : .: ** .* . :: . ::: . . * .*.: * :*.:... .*: * .. .*. *. ..:. . ** *:: : . :.* .:. .: .:: . : :::. : .:*. . : * ********.*******::**** . . *: :** .**:.*** ***********.*:*:**** :* **:***: : . * :* * :* :::::*:**. ::::: : .. : *.** ::*. ..:* :: . :***:******* ***:*: :: :*** :. : ** * *.*. * :. *** ***. **:*.::**: **::**.* . : **.:* ** * :: ****:. .* . ..** .* * *. *.:..* : *. * . . . : : :: . . . :** **: : . .* ..*: ::. *. .*. ..:::**::** * *****. : : *:. * : . : * *:: . *:.: *:*: * : * . . . *.: . :*** **: . :*:**: ***:* *********: **.*:*.****: *:*: **:***. **:*** :* *::**:**::** :*** .:***::* : :...* *:: . *. . . .. * :: ..*:****** :*:*:.* :::: : ::* *:.* * ", "identical_positions": 380, "similar_positions": 388, "identity": "18.35%" }, { "cls_id": "homologset.agr.MGI:2135958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RRU4-1", "uniprot_id": "SCAP_RAT", "id": "A2RRU4-1", "name": "Sterol regulatory element-binding protein cleavage-activating protein", "aln": "-------------------------------------------------MTLTERLREKISQAFYNHGLLCASYPIPIILFTGLCILACCYPLLKLPLPGTGPVEFSTPVKGYS----------------------------PPPADSDHKQGEPSEQPEWYVG-APVAYIQQIFVKSSVSPWHRNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGTKSLEEVCLQVTDLLPGLR-KLRSLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVS---LYTRKRMVSYTITLVFQRYHAKFLSSLRARLMLLHP----SPNCSLRAENLVHVHFKEEIGIAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNVATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLP-------------------PESCLPSAKPVGRPARYERQLAVRPSTPHTITLQPSSFR-----NLRLPKRLRVIYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRTYLAAQVTEQSPLGEGSLGPMPVPSGVLPASHPDPAFSIFP-PDAPKLPENQTLPGELPEHAVPAEGVQDSRAPEVTWGPEDEELWRKLSFRHWPTLFNYYNITLAKRYISLLPVIPVTLHLNPREALEGRHPQDGRTAWAPPEPLPAGLWETGPKGPGG-------------TQTHGDITLYKVAALGLAAGIVLVLLLLCLYRVLCPRNYGQPGGGAGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGQVCVWDAQTGDCLTRIPRPG-PRRDSCGGGAFEAQENWERLS----DGGKASPEEPG--------DSPPLRRRPRGPPPPSLFGDQPDLTCLIDTNFSVQLPP-EPTQPEPRHRAGCGRSRDS-GYDFSRLVQRVYQEEGLAAVHMSALRPPSPGPPLPQASQEEGTAPEKGSPPLAWAPSTAGSIWSLELQGSLIVVGRSSGRLEVWDAIEGVLCCSNEEISS---GITALVFLDRRIVAARLNGSLDFFSLETHTSLSPLQFRGTPGRGSSPSSPVYSSSNTVACHLT-------------------HTVPCAHQKPITALRAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYID--QTMVLASGGQDGAICLWDVLTGSRVSHTFAHRGDVTSLTCTTSCVISSGLDDFINIWDRSTGIKLYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6GQT6-1", "uniprot_id": "SCAP_MOUSE", "id": "Q6GQT6-1", "name": "Sterol regulatory element-binding protein cleavage-activating protein", "aln": "-------------------------------------------------MTLTERLREKISQAFYNHGLLCASYPIPIILFTGLCILACCYPLLKLPLPGTGPVEFSTPVKGYS----------------------------PPPADSDHKQGEPSEQPEWYVG-APVAYIQQIFVKSSVSPWHRNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGTKSLEEVCLQVTDLLPGLR-KLRSLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVS---LYTRKRMVSYTITLVFQRYHAKFLSSLRARLMLLHP----SPNCSLRAENLVHVHFKEEIGIAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNAATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLP-------------------PESCLPSAKPVGRPARYERQQAVRPSTPHTITLQPSSFR-----NLRLPKRLRVIYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRTYLAAQVTEQSPLGEGSLGPMPVPSGVLPASHPDPAFSIFP-PDAPKLPENQTLPGELPEHAGPAEGVHDSRAPEVTWGPEDEELWRKLSFRHWPTLFNYYNITLAKRYISLLPVIPVTLHLNPREALEGRHPQDGRSAWAPQEPLPAGLWESGPKGPGG-------------TQTHGDITLYKVAALGLAAGIVLVLLLLCLYRVLCPRNYGQPGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGQVCVWDAQTGDCLTRIPRPG-PRRDSCGGGAFETQENWERLS----DGGKASPEEPG--------DSPPLRRRPRGPPPPSLFGDQPDLTCLIDTNFSVQLPP-EPTQPEPRHRVGCGRSRDS-GYDFSRLVQRVYQEEGLAAMRMPALRPPSPGPPLPQASQEEGTAPEKGSPPLAWTPSTAGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSNEEISS---GITALVFLDRRIVAARLNGSLDFFSLETHTSLSPLQFRGTPGRGSSPSSSVYSSSNTVTCHRT-------------------HTVPCAHQKPITALRAAAGRLVTGSQDHTLRVFRLDDSCCLFTLKGHSGAITAVYID--QTMVLASGGQDGAICLWDVLTGSRVSQTFAHRGDVTSLTCTASCVISSGLDDFISIWDRSTGIKLYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12770-1", "uniprot_id": "SCAP_HUMAN", "id": "Q12770-1", "name": "Sterol regulatory element-binding protein cleavage-activating protein", "aln": "-------------------------------------------------MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTPVKDYS----------------------------PPPVDSDRKQGEPTEQPEWYVG-APVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLR-KLRNLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVS---LYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHP----SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLP-------------------PEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFR-----NLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFP-PDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGG-------------VQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLS----DGGKAGPEEPG--------DSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSS---GITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLT-------------------HTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYID--QTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4M5-1", "uniprot_id": "A0A8M2B4M5_DANRE", "id": "A0A8M2B4M5-1", "name": "Sterol regulatory element-binding protein cleavage-activating protein", "aln": "MYQTTMSSTISYVAVPMSYDRIISLDARRCPRPGRTRRLDGHQLTPAPRMTVRERLRQNISAAFYRHGLLCASYPVPIILFTSASILTCCYPLLKLPLPGTGPVEFTTGVRDYS----------------------------IPSHES---QGDLSERPDWYRG-PPVAYIQQVLVKAAVSPWGNSLVPVDVFRSPLGRVFSLLDEIRNHVYTD----RSLEALCLQVTDLLPGLR-RMQAVLPEHGCLLVSPGNYWQNRRDLFDADPDLLKTVHQHEPKGLHTSATLRDLLFGVPGKQTGVS---LYSKKRVVTYTVTIALSSYDARFVGSLRARLKQLHP----SANCTLREDHMVHVHFKEEIGIAELIPLVTTYIILFAYIYFSTRKIDMVRSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSNESWSIMKNMATELCIILIGYFTFVPAIQEFCLFAVVGLVSDFFLQMFFFTTVLSIDIRRMELADLNRRLP-------------------AEAGMPPPKPGTLRPR-ETPPPPRPS-PHTITLQTPAFR-----NLRLPKRLRVVYFLARTRLAQRIIMVGTVIWIGILVYTDPAGLRTFLAAQVSEQSPLGEAGLPPHLGVAPVFPGGHPTSTLSVLPAPEPTPLPENQS-----QGHRAARPGVAPVSSPQITWGSEDEELWRRLSFRHWPSLFSYYNITLAKRYISILPVIPVTLHLSPQEAIDTRHPQDTQHAPPPPPSIKT-------------------------SDLQTDLTLYKVAALGLFAGVLLVLLLFCLYRVLCPRNYGQNGVPHGRRRRGDLPCDEYGYSPPISEISPLLLRGHSMDIECLASDGMLLASCCLAGQIRVWDAQTGDCLTVIPNKG--LRRSSSNGCWEHRDGWDHISAFEVEGIATDFREPGGAMGGPDVDIFAIRRR-TTPARPALFGDQPDLTPLIDTNFGALPPS----------QALSGS-----GFDFGSLVEKAYQEHEPSPVLVFPPSPPASQQRRRSLGDQPVLPPELPP---QSSADWDSSVWAMELRGNLIATGRSTGKLELWDAVEGSLRCSNEDGVS---GITALAFLNNRIVAARLNGSLDFFTVEINKPLGLLQYRGPPGRGSLPPSPCYSSEDVISCHLT-------------------RSVQCAHQKPITVLKAAAGRVVTGSQDHTVRVYRLEDSCCLFTLQGHSGGITAIYID--QTMVLASGGQDGAICVWDVLTGSRVSHVYGHRGDVTSLVCTTSCIISSGLDDLICIWDRSTGIKLYSIQQEVGCGASLGVISENLLVTGGQGCVSFWDLNYGDLLQTVYLGPSSEGQSVRQLLVLDNAAIICDFGSELSLVYVPSVLEKLD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6J2-1", "uniprot_id": "A1Z6J2_DROME", "id": "A1Z6J2-1", "name": "Sterol regulatory element-binding protein cleavage-activating protein", "aln": "-MAAATDVSARAAAAASSTSPRTAASNSSGLAGKPPGPAPSSAGVAGAAGASSTGLPASVSHFYYKHGLFLSSYPTCASSIAFMAILLSCYPLINIPLPGTIPTKIVVPYETGSGSLSWHSLNTSSTTPQEPHPSGEPWPPEPQVLNSSTTDRSPPPLLPWAQSSPAFFYVQQITLRTSVLPWTEGMQLMDAFRAPLHEVFKLLEIVRNHQSSENK--RTLEHNCLHVDNVKRGTHGQLDQIFPEYGCLLLSPANLWTQNSQNFTRDTNILNTIFQYHN-LQKSKVSAAEMLFGLPMQDTGFKRYPLRARSRIIQYALTLFLKHNDMEYLDTLKEKLLRHYPPLPLASASAEEPTTITYIFYPGEYRMWELVPYTVAFMLVFAYVYFSVRKIDVFRSRFLLALCSVITTAGSLAMSLGLCFFFGLTISLQSKDIFPYLVILVGLENSLVITKSVVSMDETFDVKIRVAQALSKEGWHISKTLLTEITILTIGLATFVPVIQEFCIFAIVGLLSDFMLQMLLFSTILAMNIKRTEYTAEAKHLPKMLLSCTQGAGRQDFRFFGAAPALPPFVP-GTFQRSQSHPKLCFADPASVSDRTSLVNGHSSPEQRIPKRIKIVNFWARTRFFQRAFMIWMIVWICSIVYNS--GYLEQLFSMQSNGTMTATLELQRRLQAG----RGAVSSFFEGWQADGQRATSAPSGSGFSTPIKAPLAIDINETAEEMMRLRYPSFDLNYFLSNFHWSTIMKQYNISLSGHYVTLLPTIRLSHAIAPELATLLRNPQEQLQQNFQWKALAAALDPLDFNDDDVRRESPMVMAEGLPLVPKSPMEIFFAILLCCISIFVLCYTMVVFYRCICTRNYAEWRSSWHESEAP------YKQTEQILEGVPTQIAGHKHRIECLVSDGAYIISCCLKGQIRVWDARSGEQLTSISRSD------------------------------------------------------------IQISQQRTDGQTLVRKLAVSP------------------------------------------------------------------------------------VWCLDYFDNLIAVGCANGRVELWESPAGLLKCAYQEDAKRNQGITHIHLNGDRVIVARLNGRLDFYRLETYYKGKQIDWGFTSAYRRTHVRTGSTGSLGLMLQQQRCQQEASQKTTKEEMKITLEGVRLAHQQPITCMQVVNDMVFTGSQDHTLKVYCLNKSDVEYTLHGHCGPVTCLFVDRWQPGTGGSGSQDGLLCVWDLFTGACMYNIQAHDGAVSCLACAPSYVISLGTDERICVWERFQGNLLTTINISN-AYSSLLMLTPSLLVTSKMGSLIVWDVRTGQPAREVKLDFAN-LQLCPKIMMLACDSVVCDYGNEIRVVRFPIVADKCH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .:* :*.***: :*** :: .** .****:::***** *.:: . . * :* : . . * . ... *:**: ::::* ** ..: :*.**:** ..*.*:: :*** : ::** **:* :: * : :: ::**:****:**.* * : : * *.::: *:.*:. ::..: ::***:* : :*.. * ::.*:: *::*: :. . .::.:*: :* :* :. .: . :.::.: * : **:* ..:::::***:***.****:.:*:: ***.:*:*. .** **:*** :**** :*:. :******:::**** **:****** ::**:*:**.**.*.* * *. **: *: ** *:**.*****:**:***:***:***::*:*:*:::*:* * : ::** . . :*. * * : : * ::: :.. .. : *:***:::: * ****: ** :* ::** :**.. * * : :: : . * . . . :. . . : : : . :* ** **.:::. ***:*: :*:::**.* :: : *. * *:**: .: : : : :: . * : .:* :. :** :*.***.: . . * : * * : ** ****.*** : **** *:: ****::*: ** *.. . :.:* : ::.. :*.:: ..**..* :.*::*:*:: * * *: :: . *** : : . *::.***** ***: :* ::: ... . :.. : : . * ***:*** ::.. . :.*******::*: *:.* :**:**.* :* :::* *. . .**.*** :*:**::**: : : .* * *:.*.*:.* :** * *: * :*:* * : :*: . . :** ::: .****. *.: .**:. *: : * *. . * ::::* :::*::*.*: :* .* * :* .", "identical_positions": 334, "similar_positions": 387, "identity": "23.21%" }, { "cls_id": "homologset.agr.MGI:2135960", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6N7-1", "uniprot_id": "G3V6N7_RAT", "id": "G3V6N7-1", "name": "", "aln": "MHPPETTTKMSSVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPMSELSGATTSLATVALDPSSDRTSNPQDVTED---------------DGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKSPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFRSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHLDICSKTKEVNNMTIPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK-PSAKSSDVLGNLNHEYVLADITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPHWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGDALAAEQTIKHLMEAEKVKGFCQLVVAAKLKEGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNVSFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDR------NSMLRLTSIGSDEDEETETY----------QEKVHMTWTKDKYMASRGQ--------------KVKSMEGFQDLLN--MRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPR--NPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924N4-1", "uniprot_id": "S12A6_MOUSE", "id": "Q924N4-1", "name": "Solute carrier family 12 member 6", "aln": "MHPPEATTKMSSVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPMSELSGATTSLATVALDPSSDRTSNPQDVTEDPSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKSPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGILQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFRSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHLDICSKTKEVDNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVISIQGIPGLASGIITENLWSNYLPKGEIIEK-PSAKSSDVLGNLNHEYVLADITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGDALAAEQTIKHLMEAEKVKGFCQLVVAAKLKEGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNVSFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDR------NSMLRLTSIGSDEDEETETY----------QEKVHMTWTKDKYMASRGQ--------------KVKSMEGFQDLLN--MRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPR--NPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHW9-1", "uniprot_id": "S12A6_HUMAN", "id": "Q9UHW9-1", "name": "Solute carrier family 12 member 6", "aln": "MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPMSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK-PSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDR------NSMLRLTSIGSDEDEETETY----------QEKVHMTWTKDKYMASRGQ--------------KAKSMEGFQDLLN--MRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPR--NPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LGD3-1", "uniprot_id": "A0A0B4LGD3_DROME", "id": "A0A0B4LGD3-1", "name": "", "aln": "---------------MQSNSAKDD----SDEMEIIPSEHNGTVHETKNEDSGDIHRAE----------------------------------------------------------------ENQKSSIDPNLYLYDDDLETRPHISTFISSIANYENTIPAATDPDAKP--------AAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFG--DFTKDADAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKE--------DSFLRDIYCP-----DGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYRKIFSFATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVIIGWPYSWRQ-EGRNSWKTFIQTVRTVAACHMALMVPKGINFYPESNHKIG-GNIDIWWIVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMDYKETPSDNKMSLVQTIVDHHYDATKTASKVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDESTEKADGDFKSSVKPDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMVRGGGREVITIYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : ** ** :.*. .. *: :..*. : *:* *: .. :* ** *::::::***::*:::. :*** * .*.: : .: :.:***::**:***:*********:********** : .* *** *** ****************************:**********: ** ***:******:**:**.*.*:.* *:** * *:: ** **:***** :*::* *:**:**::*****:: *****:**:*:*.* :.. .. :: :*:**:* *.. :: *:* * * .::* :..*:**:: *** .::** *****:: :*::..:* **::*. ** . : .. .:: ::.*********:******************** *********** ****** ****.*::*.. ::.::******::: *:***..::**. ***:****:** ******************:*:***** *.:*. .**** ***** .*.: ***:..:**:**:********* *******:*******:*****::***:**::*:::*:::*:::***:*::** :* :*******:************::*:***::*****************:*** **:::* *: ::::**:********** *** *:. : ..*: *: *::: * *******:::** :: **:* :**: ****** ***::*** .*** *. .:***** ***..:*.*:**:*.*.:.*:*.. .::. ****:********:***********:.**:*.:*******:*********** **********:******::*****************.**** : *.*.*..: .* : * *.* : :* ... : *:* :*. * :*: * . * :* * :. :: ::**: ********:*******:**::*:**::*:***** ..* :.**************:**:***** *******", "identical_positions": 607, "similar_positions": 291, "identity": "51.22%" }, { "cls_id": "homologset.agr.MGI:2135962", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R064-1", "uniprot_id": "GORS2_RAT", "id": "Q9R064-1", "name": "Golgi reassembly-stacking protein 2", "aln": "MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSISGSRLNKDNDTLKDLLKANVEKPVKMLIYSSKTLELREASVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVESNSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGYGYLHRIPTRPFEE-GKKISLPGQMTGTPITPLKDG----FTQVQLSSVSPPSLS--PPGTAGVEQSLSGLSISSAPPAVSNVLST----GVPTVPLLPPQVNQSLASVPPMNPAATLPSLMPLSAGLPNLPNLPSLSNFNLPAPHIMPGVGLPELGKPGLPPLPSLPPRNVPGIAPLPMPSDFLPSFPLVPEGSSAASAGEPLSSLPAMG--PPSDPVMTTAKADTSS-LTVDVMSPASKVPTTVEDRVSDCTPAMEKPVSAVTDANASGAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JX3-1", "uniprot_id": "GORS2_MOUSE", "id": "Q99JX3-1", "name": "Golgi reassembly-stacking protein 2", "aln": "MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSINGSRLNKDNDTLKDLLKANVEKPVKMLIYSSKTLELREASVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVESNSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGYGYLHRIPTRPFEE-GKKISLPGQMTGTPITPLKDG----FTEVQLSSVSPPSLS--PPGTTGVEQSLSGLSISSAPPAVSNVLST----GVPTVPLLPPQVNQSLASMPPMNPATTLPSLMPLSAGLPSLPNLPSLSNFNLPAPHIMPGVGLPELGSPGLPPLPSLPPRNLPGIAPLPMLSDFLPSFPLVPEGSSAASAGEPLSSLPAMG--PPSDPVMTTAKADASS-LTVDVTSPASKVPTTVEDRVSDCTPAVEKPVS---DADASEPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8Y8-1", "uniprot_id": "GORS2_HUMAN", "id": "Q9H8Y8-1", "name": "Golgi reassembly-stacking protein 2", "aln": "MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSINGSRLNKDNDTLKDLLKANVEKPVKMLIYSSKTLELRETSVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVESNSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGYGYLHRIPTRPFEE-GKKISLPGQMAGTPITPLKDG----FTEVQLSSVNPPSLS--PPGTTGIEQSLTGLSISSTPPAVSSVLST----GVPTVPLLPPQVNQSLTSVPPMNPATTLPGLMPLPAGLPNLPNL----NLNLPAPHIMPGVGLPELVNPGLPPLPSMPPRNLPGIAPLPLPSEFLPSFPLVPESSSAASSGELLSSLPPTSN-APSDPATTTAKADAASSLTVDVTPPTAKAPTTVEDRVGDSTPVSEKPVSAAVDANASESP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW57-1", "uniprot_id": "Q9VW57_DROME", "id": "Q9VW57-1", "name": "", "aln": "MGSSHSIHVPGGGTEGYHVLKVQDNSPGQKAGLEAFFDFIVAIAGTRLDQDNDMLKELLRQNVDKPVRLTVYSSKTQTVRELTLTPSNNWGGQGLLGVSIRFCSFEGANESVWHILEVHPNSPAELAGLRAYSDYVIGADAIRHENDDLFTLIETHEQQPLKMYVYNLDDDACREVTIKPNTAWGGEGALGCGIGFGYLHRIPVQAEPVTSSSAAVPAAAAAESTAPLLTAGGAAPAGAQVAQVVSPTLPYIPPLANTFGSTNAEVRPPTIEPPAQSLFKTYFNPDEATDALTAALESQATIAEPVSVPAP--PAVADVSVAQPQVQVPAPAQPLPPPANIFIPGVFDPST-QQNANALGGIPAAQLP----FPQATAAPAAVPMFSAPQQAYMSAPAALSYPAGAQTVPSYPQVQPSMGGLFPTQPTPLPPQMAHVFAPPVPPQAGAAPAAGNDELSGPAVNQAGN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04410-1", "uniprot_id": "GRH1_YEAST", "id": "Q04410-1", "name": "GRASP65 homolog protein 1", "aln": "MFRIAKNLVRTFEQSVQDTLALSQDS----SNLDAFFQSIP--------------PNLLSAQLESPVDAVSEGVKHTNVNETLSGLRIVWVDEMQFQLQSFFDYIVGFNDDPVPVVSNQHG--------FSYPDYRR-----------ITSIFNEHCGRTLKVNIWSAKGGTFRDEYISIISKESDD---LDDVSLNHDERRPSSGEAHQFQALGFKVQWTPLIASTFTYH----ILNVNIPDGPAQSAG-LIPDEDYIIGCQDGLLATGGETLLQDIVRS-----RANYDLVLYVYNKVSDCVRPITVHIGPDGRLGCNVGYGFLHRIPTVKHCPQQAQQQGQ--------------------------------DDNPVPVPVPVESETAFVPSAFT---------APPVPTKKKSKNKKGT-----QPLAMDDYFNEGRDKSSTAAKSAESDILAPPPQKQSSSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . ..* :.::* :.*:.**: * :** :::.** . * :.* * .: : :. * : * *:. ::. . . .:.** : :::: * :.**: ::. . . *: *. : ..: .:. .: .* * . .. : :.: .::.. . : * . : . . ..:. : .. * .: . . .. : * ..*: . * .. *. * : . . . .: . . : ", "identical_positions": 33, "similar_positions": 111, "identity": "7.05%" }, { "cls_id": "homologset.agr.MGI:2135965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q52RG8-1", "uniprot_id": "FRS3_RAT", "id": "Q52RG8-1", "name": "Fibroblast growth factor receptor substrate 3", "aln": "MGSCCSCLDRDSVPHNHPTKFKVTNVDDEGVE----LGSGVMELTQSELVLHLHQQEAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCN-SINVTEEPVIITRNSHPQELDLPRGSSQP--TGYTVSSFSNGFPGCPGEGPRFSSAPRRPSTSSLRHPSPGEESTQTLIASDEQSHTYVNTPTGEED-RRSRHCLQPLPEGRVPFPPQTQVSD----------------------QRDPQVFLQPG--QVKFVLGPTPARRQVMK---------------CQSLCPSMQDPPLHNNN-EGPSECP------------AQPKCTYENVSGGLQQGAGWRLSPE----------------------------------------------ERGWSGLAHRRAALLHYENLPPLPPVWESQVQQLRGEAGDDGDSKDGLTPSSNG-------FPDGEEDETPLQKPTS----TRASARSHS---SFPVPLTRRRGSP----------RVFNFDFRR----------------PGPEPPRQLNYIQVELKG---------WGTAHPKGPQNPSVSGAPGPTPHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTVRKTRHNSTDLPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WJ0-1", "uniprot_id": "FRS3_MOUSE", "id": "Q91WJ0-1", "name": "Fibroblast growth factor receptor substrate 3", "aln": "MGSCWSCLDRDSVPHNHPTKFKVTNVDDEGVE----LGSGVMELTQSELVLHLHQREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEDIFNLLQDLMQCN-SINVTEEPVIITRSSHPPELDLPRGPPQP--AGYTVSGFSNGFPGCPGEGPRFSSAPRRPSTSSLRHPSPGEESTHTLIASEEQSHTYVNTPTGDED-GRSRHCLQPLPEGRVPLPAQTQGSD----------------------QRDPQVLLQPG--QVKFVLGPTPARRQVMK---------------CQSLCPGMQDPPHHNNN-EGPSECP------------AQPKCTYENVSGGLQQGAGWRLSPE----------------------------------------------ERGWSGLAHRRAALLHYENLPPLPPVWESQGQQPGGEAGDDGDSRDGLTPSSNG-------FPDGEEDETPLQKPTS----TRASARSHS---GFPVPLTRRRGSP----------RVFNFDFRR----------------QGPEPPRQLNYIQVELKG---------WGTARPKGPQNPSVSGAPGPTPHPVRSSDSYAVIDLKKTAAMSDLQRALPRDDGAVRKTRHNSTDLPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43559-1", "uniprot_id": "FRS3_HUMAN", "id": "O43559-1", "name": "Fibroblast growth factor receptor substrate 3", "aln": "MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVE----LGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCN-SINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSN---GCPGEGPRFS-APRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPD----------------------QRDPQVFLQPG--QVKFVLGPTPARRHMVK---------------CQGLCPSLHDPPHHNNNNEAPSECP------------AQPKCTYENVTGGLWRGAGWRLSPE----------------------------------------------EPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNG-------FPDGEEDETPLQKPTS----TRAAIRSHG---SFPVPLTRRRGSP----------RVFNFDFRR----------------PGPEPPRQLNYIQVELKG---------WGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F020-1", "uniprot_id": "E7F020_DANRE", "id": "E7F020-1", "name": "", "aln": "MGSCWSCLYRDAIQDNHLNKFKVTNVDDEGNE----LGSGTMELTQTELILHTRKRDAIRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQELMQCN-SINVVEEPMIMTRPGHAPEMDMPRTPQTPNTPAFPMQGFPN---GYPG----------YPISADSSQPSLTNDHRHSLMGLDDQTHTYVNTVGMETD-LSSRHCVHSLPEVRPATYPEATTTTTTIRGGPIPGQPGMHCCPLDDPHKDPQVFLQPGAQEVKFMLGPTPAQRHLMERDRERHVPHSLRAPDGSSETEGEETPPVHMCNTHSYHHCHHLMHRHPSMEPCPESQLTYENING-LRGARRQRLSPSTVSQSQSLGSSSSSSTTGDSRTHTHPHSLPLTHTHTSSLPPQGYGCDRGMVAAGHRRTALLNYENLPSLPPVWEYRALQREEEEDQDEDEDEDEYEEEEEEEYDEYEYSEGPATPNGYHQESGGGGIHRDALQNYVNTEQLPPPTRLRHACPPHPHPPERANRVFNFDFRRQRAGRGSSICEQHSRHPPPPPSRQLNYIQVDLEGEPSGCSGHSGGAPVPQRPPPLKRGMAAAAAPPSSRRGECYAVIDLKKTAAMSNLQKALPRDDGTSRKTRHNSTDLPL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLL4-1", "uniprot_id": "Q9VLL4_DROME", "id": "Q9VLL4-1", "name": "IRS-type PTB domain-containing protein", "aln": "MG-CITSSSKLNELRGHENVFRVRVAHLQPTPGTPIIRSGYLELTPRELIFQSPGCEPIVWALQHLRRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYPMFQRYINAVNTDAFVQGERERVNSAHSVSVNMGRTEGNNYLEPAPLMSRQLG------------NFHSEPSSTSASYPLQANDSQVDDSPPNLQSPVLIPSAYLDQPLRALQDCCLEG--------------------------------------------------TASDLLSTPPSGNRLTS------------------RRRTMDLPPLESAPAPAPVLSP------------NDAVHMYANVEALIFDLNN----------------------------------------------------ERCYENVNRLELPLLPREPISNQEPATPTSLAGSCGVNYIVLDLDQPRS-------------PVGPAGSSKAINGFG----SGLSLISTP--AAVTAPVTPEAGTT--------------LDVPP-----------------PPMQTQSLNSISADTGDT------QAKKVTECSGTQGYSTIDFIRTYALNKSSTELPETVTHRQHSSHDAEELRITRHSKCIRKAYSISE----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :. : .* . *:* .. : : ** :*** **::: :.: *. ***** :.:*****:**** :* **::*: .**::: ::* ::. : . : .. .*. .::: * .: . ::. * :: : *: . : : : :.* .. :*...*: .:: . . ** . . . :. * *: . : : : . .** * :. *. * : . * . : . : . .. * . . . :*. * .:.** *..: . . . . . . : .: :: : . : :.*.. **: * ", "identical_positions": 62, "similar_positions": 128, "identity": "9.58%" }, { "cls_id": "homologset.agr.MGI:2136018", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3K6-1", "uniprot_id": "D4A3K6_RAT", "id": "D4A3K6-1", "name": "Protein Wnt", "aln": "MDRAALLALPSLCALWAAVLSLLPCGTQGNWMWLGIASFGVPEKLGCSGLPLNSRQKELCKRKPYLLPSIREGARLGIQECRSQFRHERWNCMV-ATATSTQLATAPLFGYELSSGTKETAFIYAIMAAGLVHSVTRSCSAGNMTECSCDTTLQNSGSASEGWHWGGCSDDVQYGMWFSRKFLDLPVRNTTEKESKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGYFLKDKYENSIQISDKTKRKMRRREKDQRQTPILKDDLLYVHKSPNYCVENKKLGIPGTQGRECNRTSGGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTSLNHRVFFLLTSLGPFKNPWQEYSKYRGECQQQTTELRIEPPLKESEKELEELEGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYS1-1", "uniprot_id": "WNT16_MOUSE", "id": "Q9QYS1-1", "name": "Protein Wnt-16", "aln": "MDRAALLALPSLCALWAAVLSLLPCGTQGNWMWLGIASFGVPEKLGCADLPLNSRQKELCKRKPYLLPSIREGARLGIQECRSQFRHERWNCMV-ATTTSTQLATAPLFGYELSSGTKETAFIYAIMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSPSEGWHWGGCSDDVQYGMWFSRKFLDLPIRNTTGKESRVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHFLKDKYENSIQISDKTKRKMRRREKDQRQTPILKDDLLYVHKSPNYCVENKKLGIPGTQGRECNRTSGGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBV4-1", "uniprot_id": "WNT16_HUMAN", "id": "Q9UBV4-1", "name": "Protein Wnt-16", "aln": "MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEKLGCANLPLNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WVL3-1", "uniprot_id": "A5WVL3_DANRE", "id": "A5WVL3-1", "name": "Protein Wnt", "aln": "MDNTG-CGIHAVHHLFLIWLSVYPLCSQGSWMWLGITSVGVPEKLGCAHLPLSHKQKELCARKPHLLPSVKEGARLGITECQTQFRHERWNCST--------RRDPNVFGYELTSGTKETAFIHAVMAAGLVHAVTRSCSAGNMTECSCDTSLLGSGSPTEGWHWGGCSDDIAFGTSFSRRFIDSAAKNTSTRGEEALLIMKQHNSEAGRQAVAKTMLTDCRCHGVSGSCAVKTCWRTMAAFERVGAYLKDRYETSVHVVDRSKRKVRRKDKEQRHVPITKDELIFFNKSPNYCLEDRRLGVTGTRGRKCNRTSAGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMNDMHTCK------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:. .: : *: * : * :**.******:*.********: ***. :***** ***:****::******* ** :********* . :*****:*********:*:*******:*****************:* ..**.:***********: :* ***:*:* . **: : ...** *: **.********* * .*****************:**::**::* ***:**.*::: *::***:**::*:**: ** **:*::.:******:*:::**:.**:**:***** *.***************************:***********:*.*:**. ", "identical_positions": 234, "similar_positions": 79, "identity": "55.85%" }, { "cls_id": "homologset.agr.MGI:2136171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GGV9-1", "uniprot_id": "A0A8I6GGV9_RAT", "id": "A0A8I6GGV9-1", "name": "", "aln": "--------------------------------------------------MEISNMNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK--------------------------DYIGDRSIPKLVAIPKPAVPTTTDEKANPNFFEQRH----------------------GGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRSSAGGS-GASGSGQRHDRDSY------------------SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLSSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSR------------------------VPFSSGQHSSQSFPP----------------------SLMSKSSSMLQKPTAYVRP----------------------------------------MDGQESVEPKLSSEHYSSQSHGSNMTELKPSSKAHLTKLKIP-------------------SRPLDASVSGDVSCVDEILKEMTHSWPPPLT-------------------------------------AIHTPCKTEP-----SKFPFP-TKESQQSNFGSGEQKRYSTSAKTSNGHQSK-------SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS--------------------------RDDSSSHSGSESSSGSDSESESS-----------------------------SSDSEANEPS-----------------QSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQA--YKKEGREQGTASNYTDPGGAKEASSATPGRDSK----------TIQKGSESGRGR-QKSPAQSDSTTQ-------------------RRTVGKKQPKKTEKS-AAEEPRGG------------------LKIESETPVDMATSMPSSRHKAATKGSRKPNIKKESK-SSPRPTAEKKKYKSASKSSQKSREIIETDSSSSDS-------------------DERESLPPSSQ--------------------------------------TPKYPESNRTPVKPSSAEEDDSFFRQRMFSPMEEKELLSPLSDPDDRYPLIVKIDLNLLTR--------------------------------------------------IPGKPYKETEPPKGEKKNVPEKHSREVQKQASEKASNKG-KRKHKNDDDNRASESKKPKTEDKNSSAHKPSSSKESSKQSSTKEKDLLPSPAGPVPSKDSKTEHGSRK-----RTVSQSSSLKSSSTSNKENSGSSK--STSSTAKQKKTEGKVSSSSKEAKEKAPNSSSNCPPSTPTPDSSKPRRTKLAFDDRNYSAD-----HYLQEAKKLKHNADALS--DRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSDTVELIKYT-MKLKNYLAPDAT----AADKRLTVLCLRCQSLLYLRLFKLKKENALKYSKTLTEHLKNSYSNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGSYSSGGSSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE--QKEFFAELDKVMGPLIFNASIMTDLARYTRQGLHWLRQDAKLIS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESC8-1", "uniprot_id": "AFF4_MOUSE", "id": "Q9ESC8-1", "name": "AF4/FMR2 family member 4", "aln": "-------------------------------------------------------MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK--------------------------DYIGDRSIPKLVAIPKPAVPTTTDEKANPNFFEQRH----------------------GGSHQSSKWTPVGPAPSTSQSQKRSSALQSGHSSQRSGAGGS-GASSSGQRHDRDSY------------------SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLSSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSR------------------------GPFSSGQHSSQSFPP----------------------SLMSKSSSMLQKPTAYVRP----------------------------------------MDGQESVEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIP-------------------SRPLDASVSGDVSCVDEILKEMTHSWPPPLT-------------------------------------AIHTPCKTEP-----SKFPFP-TKESQQSNFGPGEQKRYST-AKTSNGHQSK-------SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS--------------------------RDDSSSHSGSESSSGSDSESESS-----------------------------SSDSEANEPS-----------------QSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQA--YKKEGREQGTASNYTDPGGTKETSSATPGRDSK----------TIQKGSESGRGR-QKSPAQSDSTTQ-------------------RRTVGKKQPKKPEKS-AAEEPRGG------------------LKIESETPVDMAASMPSSRHKAATKGSRKPNIKKESK-SSPRPTAEKKKYKSASKPSQKSREIIETDTSSSDS-------------------DGSESLPPSSQ--------------------------------------TPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTR--------------------------------------------------IPGKPYKETEPPKGEKKNVPEKHSREVQKQASEKASNKG-KRKHKNDDDTRASESKKPKTEDKNSSGHKPSSSRESSKQSSTKEKDLLPSPAGPILSKDSKTEHGSRK-----RTVSQSSSLKSSGTSSKENSGSSSKSSSSSTAKQKKTEGKGPSSSKEAKEKAPNSSSNCPPSTPTSESSKPRRTKLAFDDRNYSAD-----HYLQEAKKLKHNADALS--DRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSDTVELIKYT-MKLKNYLAPDAT----AADKRLTVLCLRCQSLLYLRLFKLKKENALKYSKTLTEHLKNSYSNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGSYSSGGSSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE--QKEFFAELDKVMGPLIFNASIMTDLARYTRQGLHWLRQDAKLIS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHB7-1", "uniprot_id": "AFF4_HUMAN", "id": "Q9UHB7-1", "name": "AF4/FMR2 family member 4", "aln": "-------------------------------------------------------MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK--------------------------DFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRH----------------------GGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYN--------------NSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSR------------------------VPFSSGQHSTQSFPP----------------------SLMSKSNSMLQKPTAYVRP----------------------------------------MDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIP-------------------SQPLDASASGDVSCVDEILKEMTHSWPPPLT-------------------------------------AIHTPCKTEP-----SKFPFP-TKESQQSNFGTGEQKRYNP-SKTSNGHQSK-------SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS--------------------------RDDSSSHSGSESSSGSDSESESS-----------------------------SSDSEANEPS-----------------QSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQG--YKKEGREQGTGNSYTDTSGPKETSSATPGRDSK----------TIQKGSESGRGR-QKSPAQSDSTTQ-------------------RRTVGKKQPKKAEKA-AAEEPRGG------------------LKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESK-SSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS-------------------DESESLPPSSQ--------------------------------------TPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTR--------------------------------------------------IPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKG-KRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRK-----RTISQSSSLKSSSNSNKETSGSSK--NSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSAD-----HYLQEAKKLKHNADALS--DRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYT-MKLKNYLAPDAT----AADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE--QKEFFAELDKVMGPLIFNASIMTDLVRYTRQGLHWLRQDAKLIS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BL85-1", "uniprot_id": "A0A8M2BL85_DANRE", "id": "A0A8M2BL85-1", "name": "", "aln": "------------------------------------------------MASQSGNMNREDRNVLRMKERERRNQEIQQGGEAFPANSPLFPEPIKVA-KEDKLSSRIQSMLGNYDEMK--------------------------ETIGEPPMSKLISKAS----SSSSEDKSGQYGDQRG----------------------GSQTQSSKWTPVGPASGGGNS---SSSSQKRSTVQSVSQKSS----SSGQRHERDYS-------------------GSKKSSKHSNEHKSHSSSSPAK------VSSNHSR-----------RVPKSPRDREANWDSPSIP-----------------------HSFPSG-HPNQTFPP----------------------SLIK-SSSMPQKPTAYVRP----------------------------------------MDGQETTEAKTSSDSYSGQSHSSTVGEMKPNGKGPLPKLKIP-------------------TQPPEA---GDASCVDEILKEMTQVWPPPLT-------------------------------------AIHTPCKTEPP----SKFPFSNAKDAQHQSVG--AQKKFSG-KSASTSHPSKPCDSEQSNMLHDDLKLSSSEDSDGEQDPAKNTPQNNSTSNNS---NNSEGAE----------------------------REDTSSHSGSESSSGSDSESESS-----------------------------STDSETTEPP-----------------RAATPEREQPTANKWLLDNWLNKVN--KLSPASPVENSSSSTPGTKYKKEGRDTSSSRSYSGQ-GSKEAATS-AGRELR----------PNQKSSESWRGRSQKSPAQSEGTSQS-----------------GRRVVGKKQPKKPEKPPVVEEPKGG------------------LKVETEP----SPEIPSHRARAPNKGLRKPNIKKEPKTSSPRPPPDKRKTKAAKVPS-KSREFIESDSSTSDS-------------------EGNESDPLPSQ--------------------------------------TPKDYSEN--PLVP-----------------------LSPIYDPPR---LLVQINLSLLTR--------------------------------------------------VPGQLYNETEV-KVERGSPAEGKS--NQKQPGEKISKEGRKRKHKNEDDGVKPESKKSKLDEKSS---RKSSSNDSSKRAQEKEKESAPSPS-ITLQRTPKSEQQGRK-----RTLSQSS----STVPSKDKS--------SSSSRHRRGDDK--PQRREPKEKS--SKSENPVSVPPLSEGSKSRSKLLFEDRVHSAD-----HYLQEAKKLKHNADALVRMDRFEKAVYYLDAVVSFIECGNALEKNAQEAKSPFPMYAETVELIKYT-MKLKSYMAPDAT----SQDKRLAVLCLRCQALLYLRLFKLRKESALKYSKTLTEHLKNSLSNTQAPSPGVANKSAGMPSPVSPKLSPGSAGSYSSSSSSQSAS-SSVTIPQRIHQMAASYVQVTSNFLYATEVWDQAEQLAKE--QREFFTELDKAMGPLIFNTSSMTDLVRFTRQGLHWLRLDAKLIQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQI9-1", "uniprot_id": "AFFL_DROME", "id": "Q9VQI9-1", "name": "AF4/FMR2 family member lilli", "aln": "MAQQQQQQMQQQQQHHTSSINNNNSSSIVLLQQQQPQQQQQQLDQLQQYNNNLYSQNYNMEEYERRKRREREKIERQQGIQIDDRETSLFGEPRRLTEGDAEITAALGEFFEAREYINNQTVGISRSAPGAGNPRLQPNLAPQAKSLGHSPSSASSAAGPTAASATTSLPGQQQHYQQQQRPPTYVKQADNKPPYNGRGGYPGQPMKNDIPSSSGMAPPRGPPRTSSSNSNSSSVTNNASSGGVPASTPLGPPLSTQMPNGREKSFLGPPAPALHNGTGGRFVPPAASKRPGVGQQPPPPEKDVNKIISDIANIFTVQPLTLIAATPHAPTRENYNLLAPNRQKYAMDIPSSPPSAEPSSLMTPLFAPITSPIAPLVTTPPQASQMPLGGATSGTILAGEALAPLHQLPPTMPKAASGVTSPGPVKPLKTEKNHSLEKQDSCLENDLELSESEDEQRKKEGRSGGNSSNSSESDSSESGSESSSKNDLQHHPNHQQHHHQLQQQQQQQQATMQQQQVLQQQHRSQPLTSNGAQNKKFRHEIIARGSNTITGLLSSSGFGSGGNVGPAGVNSNAVVGTGSGSGGTLSSGGSSSNKTPSPTESNKWNLSRFFHKPANQTNSESVSPGNVSMKVPGILPGGAQIIPESIDVTTAIVKNEKNDMAMEEGEEEDDDEEQQLRYGGGLSVTPVAVKKEAIDAVSEMALGAIPKTQIKRESAETLLSARLSDSGTSASGSSSSSSSSSDSAMGGEVVPMPGPGETLQLPGVPAAITTVMRVQPTQSQKAPPSNSVTLTPILPLPTSPKQRQKKPRKKKAITSAPILDSSDDDEPPPKHPGLDHTAVSVQTQPATDTVKKGRGRPRKQQQSGGSGNLSSASAGSSSQTKGPTLTAAKKPLAKTPLAMSRARKREHSSQSSSNGNTPTKKVATPQLVAAPLKPTSNTAGSSSSDEDSSSSAESSSKSSSSSSSSDDTETQNTNCRIVKLNKTGAVQKKALLGSGSSSPSSSGSEAEDQTTRSQVGSGQALAQQLPPYKQLPISQHSQHLSSSDCSSSSGGCTAVCSSSSGEEDEGRREKERERKPKSDKNKINTLTRIFNPKEGGAKKQGQVVIVDLQEEQQQGKLDAAAQPSAPQAPPAAPAAIMAKPRMTPTQQQQLGAGLASPARTTTPHLTSLICKIDLSKLSRERIMRLKKLTPAQQNGHLTPKDQATNAVHVPNGYAGDTNPAAKVKHEHPVKPEPELDAGYEAKFKPGNVKQEFQLKQERDRDRERERERERERERDREREQPPGRRRKRSSSSSSSPYKEKKRKKEKADQLQMGKELLPVPVLLPSNNHERMPNHDRLSYDKLQLLHEDAAAVIGDVSAPNGSPTKKLLAMSPLPPPPTVTVAPATCNEAVQTTPPSATATSAIAPPVPATRLIYRSYFDRDVEHPSDDPRKNNQFLQEAINRKHAADLER--DSFNQVTLYLEAVVYFLLTADAMERCSSE-QATNTMYKDTLSLIKFISTKFRPYQQQSTTNIQHETHNKVAILSLRCQSLISLKLYKLRRKDCRAIINSLTDFFRVGRGDIANGN---------TPSSISPSNSVGSQG-------SGSNTPPGRIVPPDIHNMLCKQNEFLSYLNSAHELWDQADRLVRTGNHIDFIRELDHENGPLTLHS-TMHEVFRYVQAGLKTLRDAVSHPTHQSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .: * *.***.: * *** : .:.** ** ::: : :::: : .:: : :: . :*. . . : .::. . :. :*: * :.. :. * *. . . ** :. : . . * . : ..: ..:: ...* : *. :. .::* : * :*. .:.* . : ** .* . . :* : .:. . * .*:.: ..: .*. ..:* ... : :*. : :*: ::* : : . .**: . :: . *: : :**. **. *:* . ::::: .... . .. .: ::::: : : *:.: *:* : : . :.*. : :. :* ***.***.*.*:* . .::*: *. : .*. : . :. **. :. * . . . . : . *:** . :. * .:::: .. : : :. *.* :: .:**... : ...*.....: ... . ...:.. :*::. . : * ....* . : ....: .* :. .:: * :*:.: .:* *:*.. . * * ..: :. . * . .. . *: :*:*. *:* * . * : . : ::: ..: ..: :.:.:: : . :: : ....* : .. .... *: * * .. : : .* : : :.: . . : * *. . . . : .. :.: . : * *: : : . * * ::**** : ** ** * *::.. **:*** *: .:*:*: :.* ::. .** :*:.***: *:: * .:* .:::::*.***::*: *:*:**:::.. ::**:.:: . .: . **.:**. * *. * * * : .. :* **:* .. :. * : * *:****::* : : :*: ***: *** ::: * :: *:.: **: ** .. ", "identical_positions": 180, "similar_positions": 432, "identity": "10.63%" }, { "cls_id": "homologset.agr.MGI:2136282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7T2V2-1", "uniprot_id": "ST1S3_DANRE", "id": "Q7T2V2-1", "name": "Cytosolic sulfotransferase 3", "aln": "------------------------MEISDFSSMKLNSRPELIDFEGISMIHYFTDNWEKVKNFQARPDDILIATYPKAG--------TTWVSYILDLLYFGNESPERQTSQPIYMRVPFLEACFEGIP--FGTELADNLPTSPRLIKTHLPVQLVPKSFWEQNSKVVYVARNAKDNAVSYFHFDRMNMGQPEPGDWNTFLQKFMEGRNVFGPWYDHVNGYWKKKQTYSNILYMFYEDMVENTGREVERLCSFLGLSTSAAERERITKGVQFDAMKQNKMTNYSTIP--VMDFK-----ISPFMRKGKVGDWRNHFTVAQNEQFDEVYKQKMKNTTVKFRTEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZUS4-1", "uniprot_id": "ST2S2_DANRE", "id": "Q7ZUS4-1", "name": "Cytosolic sulfotransferase 2", "aln": "------------------------MEIPDFSSMKLDSRPELIDFEGVSMTRYFTDNWEKVKNFQARPDDILIATYPKAG--------TTWVSYILDLLYFGNESPERQTSQPIYMRVPFLEMCFQGLP--LGTELADTLPTSPRPIKTHLPVQLVPKSFWEQNSKVVYVARNAKDNAVSYFHFDRMNMGQPEPGDWNTFLQKFMDGRNVFGPWYDHVNGYWKKKQTYSNILYMFYEDMVEDTGREVARLCSFLGLSTSATERERITKGVQFDVMKQNKMTNYSTLP--VMDFK-----ISPFMRKGKVGDWRNHFTVAQNEQFDEVYKQKMKNTTVKFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PH37-1", "uniprot_id": "ST1S1_DANRE", "id": "Q6PH37-1", "name": "Cytosolic sulfotransferase 1", "aln": "------------------------MDIPDFSSIS--SRPTIFEFEGISMINHFTENWEKVKNFQARPDDILIATYPKAG--------TTWVSYILDLLYFGENAPEEHTSQPIYMRVPFLESCFKVIA--SGTELADNMTTSPRLIKTHLPVQLIPKSFWEQNSRVVYVARNAKDNVVSYFHFDRMNIVEPDPGDWNTFLHRFMDGKSVFGPWYDHVNGYWEKKQTYSNLLYLFYEDLVEDTGREVDRLCSFLGLSTSVSDREKITKDVQFDAMKQNKMTNYSTLP--VMDFK-----ISPFMRKGKVGDWKNHFTVAQNEQFDEVYKEKMKNATVKFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PQS2-1", "uniprot_id": "A0A8M9PQS2_DANRE", "id": "A0A8M9PQS2-1", "name": "Sulfotransferase", "aln": "---------------------MTDHEFPDVASMKPCIRPDMFDFEGVFLTRFFTDNWENVKNFQARPDDILIATYPKAGYSAIKNPRTTWVSYILDLLYFGND--ENQTSQPIVQRVPFLESCFQEFSTISGTEMADNLPTSPRLIKTHLPVQLVPKSFWEQNSRVVYVARNAKDNAVSYFHFDRMNMVQPEPGDWDSYLDKFMQGQNVFGSWFDHVSGWWQKKRSYPNMLYMFFEDLSEDTGREVNRLCSFLGLSTSVQEKEKITKGVQFDAMKQNTLINHVTIP--FLDCK-----ISPFMRKGKVGDWKSHFTVAQNERFDEVYKQKMKNSGVTFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A8R3-1", "uniprot_id": "A0AB13A8R3_DANRE", "id": "A0AB13A8R3-1", "name": "Sulfotransferase", "aln": "------------------------MEIQGKSSTDLPDRPEIFEFEGISMVEHFTKNWENVKNFQARPDDILIATYPKAG--------TTWVSNILDLLYFGKEDPKRQTTKPIYKRVPFLESCFPEMQ--SGTELANNLPTSPRLIKTHLPVQLVPQSFWEKNSRVAYVARNAKDNAVSYFHFNRMNKAQPEPGDWNTFLEEFMKGKMVFGSWFDHVCGWWEKKKTYPNLHYMLYEDMAKDIKGEVESLCTFLKLSRSDEEKEKIINGIQFDAMKQNKMTNYSTVL--VMDFT-----ISPFMRKGKVGDWKNHFTVAQNEQFNEDYKQKMKNSTLKFPTEHGRKTRGGRGRHVPSHPRLVPPPQKRKNLNYKKKNLNCEKYTYIYLK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52847-1", "uniprot_id": "ST1B1_RAT", "id": "P52847-1", "name": "Sulfotransferase 1B1", "aln": "-----------------------------MGTAEDVFRKDLKIIHGYPMVYAFALGWEKIEEFQSRPCDIVIPTYPKSG--------TTWLSEIVDMVLNDGN-VEKCKRDVITSKVPMLEQNVPGARR-SGVELLKKTP-SPRIIKTHLPIDLLPKSFWDNKCKMIYLARNGKDVAVSYYHFDLMNNIQPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREGHP-ILFLYYEDLKKNPKKEIKKIANFLDKTLDEHTLERIVHHTSFEVMKDNPLVNYTHLPTEIMDHS-----KSPFMRKGVVGDWKNYFTMTQSEKFDAIYKKKLSGTTLEFCTDIQSA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWG7-1", "uniprot_id": "ST1B1_MOUSE", "id": "Q9QWG7-1", "name": "Sulfotransferase 1B1", "aln": "-----------------------------MSASEDVWRKDLKMIHGYPMIYAFALNWERIEEFQSTPGDIVITTYPKSG--------TTWLSEIVDMVLNDGN-VEKCKRDVITSKVPMLELSVPGIRI-SGVELLKKTP-SPRIIKTHLPIDLLPKSFWENKCKMIYLARNGKDVAVSYYHFDLMNSINPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREEHP-LLYLYYEELKQNPKKEIKKIASFLDKTLDEEALDRIVHHTSFEMMKENPLVNYTHLPTAMMDHS-----KSPFMRKGIVGDWKNYFTMTQTEQFDAVYKKKMSGTTLEFCTDIQSA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43704-1", "uniprot_id": "ST1B1_HUMAN", "id": "O43704-1", "name": "Sulfotransferase 1B1", "aln": "-----------------------------MLSPKDILRKDLKLVHGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSG--------TTWVSEIIDMILNDGD-IEKCKRGFITEKVPMLEMTLPGLRT-SGIEQLEKNP-SPRIVKTHLPTDLLPKSFWENNCKMIYLARNAKDVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKKKEEHP-ILFLYYEDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLPTTVMDHS-----KSPFMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1L8-1", "uniprot_id": "Q9W1L8_DROME", "id": "Q9W1L8-1", "name": "", "aln": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCG--------TTWMQELAWLVINECD-FETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAIS-YFHHWRGMVG-YQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLR-HEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF40-1", "uniprot_id": "A0A0B4KF40_DROME", "id": "A0A0B4KF40-1", "name": "", "aln": "---------------MNRVQVTP-------RSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCG--------TTWMQELLWLLLNNCD-FEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSRYYHGVSFGFN-YGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLR-NEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHEN-AGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : ::. *: * * **.* ***:. : :: : : : *:** *** :*:**. ::* .:*. . :: *: ** * :* :.. ::. .: . * ::: : . : : :* : : : : ** . ::: . .* *:.* *: . *:*:* ... :. :. .. : . : : : ", "identical_positions": 36, "similar_positions": 77, "identity": "6.43%" }, { "cls_id": "homologset.agr.MGI:2136335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI74-1", "uniprot_id": "KLHL1_MOUSE", "id": "Q9JI74-1", "name": "Kelch-like protein 1", "aln": "MSGSGRKDFDVKHILRLRWKLFSHPSPASSSPAGGSCLQQDSGGGSFEHWGPSQSRLLKNQEKGSVSAFWKKPSSSSSSSSSSSSSASSSPFNPLNGTLLPVATRLQQGAPGQGTQQPARTLFYVESLEEEVVTGMDFSGPEDKGLALKELQAEPASSIQATGEGCGHRLTSTNHSLTPQSDLDSSSSEEFYQAVHHAEQSFRKMENYLKQQQLCDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAKQEEIKMEGIDPNALWDLVQFAYTGCLELKEDTIENLLAAACLLQLPQVVEVCCHFLMKLLHPSNCLGIRAFADAQGCIELMKVAHSYTMENIMEVIRNQEFLLLPAEELHKLLASDDVNVPDEETIFHALMMWVKYDMQRRCSDLSMLLAFIRLPLLPPQILADLENHALFKNDLECQKLILEAMKYHLLPERRTLMQSPRTKPRKSTVGTLYAVGGMDNNKGATTIEKYDLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGRDGLKTLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVGGHDGWSYLNTVERWDPQSQQWTYVASMSIARSTVGVAALNGKLYSVGGRDGSSCLSSMEYYDPHTNKWSMCAPMCKRRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYDPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGGYDGQTYLNTMESYDPQTNEWTQMASLNIGRAGACVVVIKQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A9J8-1", "uniprot_id": "D4A9J8_RAT", "id": "D4A9J8-1", "name": "", "aln": "MSGSGRKDFDVKHILRLRWKLFSHPSPASGSSAGGSCLQQDSGGGSFEHWGPSQSRLLKNQEKGSVSAFWKKPSSSSTSSSSSSS-ASSSPFSPLNGTLLPVATRLQQGAPGQGTQQPARTLFYVESLEEEVVTGMDFPGPQDKGLALKELQAEPASSIQATGEGCGHRLTTTNHSLTPQSDLDSSSSEEFYQAVHHAEQSFRKMENYLKQQQLCDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAKQEEIKMEGIDPNALWDLVQFAYTGCLELKEDTIENLLAAACLLQLPQVVEVCCHFLMKLLHPSNCLGIRAFADAQGCIELMKVAHSYTMENIMEVIRNQEFLLLPAEELHKLLASDDVNVPDEETIFHALMMWVKYDMQRRCGDLSMLLAFIRLPLLPPQILADLENHALFKNDLECQKLILEAMKYHLLPERRTLMQSPRTKPRKSTVGTLYAVGGMDNNKGATTIEKYDLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGRDGLKTLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVGGHDGWSYLNTVERWDPQSQQWTYVASMSIARSTVGVAALNGKLYSVGGRDGSSCLSSMEYYDPHTNKWSMCAPMCKRRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYDPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGGYDGQTYLNTMESYDPQTNEWTQMASLNIGRAGACVVVIKQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NR64-1", "uniprot_id": "KLHL1_HUMAN", "id": "Q9NR64-1", "name": "Kelch-like protein 1", "aln": "MSGSGRKDFDVKHILRLRWKLFSHPSPSTGGPAGGGCLQQD-GSGSFEHWGPSQSRLLKSQERSGVSTFWKKPSSSSSSSSSPSS--SSSSFNPLNGTLLPVATRLQQGAPGQGTQQPARTLFYVESLEEEVVPGMDFPGPHEKGLVLQELKVEPDNSSQATGEGCGHRLSSTGHSMTPQSDLDSSSSEEFYQAVHHAEQTFRKMESYLKQQQLCDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAKQEEIKMEGIDPNALWDLVQFAYTGCLELKEDTIENLLAAACLLQLPQVVEVCCHFLMKLLHPSNCLGIRAFADAQGCIELMKVAHSYTMENIMEVIRNQEFLLLPAEELHKLLASDDVNVPDEETIFHALMMWVKYDMQSRCNDLSMLLAFIRLPLLPPQILADLENHALFKNDLECQKLILEAMKYHLLPERRTLMQSPRTKPRKSTVGTLYAVGGMDNNKGATTIEKYDLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGRDGLKTLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVGGHDGWSYLNTVERWDPQSQQWTFVASMSIARSTVGVAALNGKLYSVGGRDGSSCLSSMEYYDPHTNKWNMCAPMCKRRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYDPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGGYDGQTYLNTMESYDPQTNEWTQMASLNIGRAGACVVVIKQP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************::...***.***** *.***************.**:..**:*********:****.** ***.*.****************************************.****.**.:***.*:**:.** .* ***********::*.**:***********************:*****.**************************************************************************************************************************************************************************************** **.*********************************************************************************************************************************************************************************************:*********************************************.************************************************************************************************************************", "identical_positions": 711, "similar_positions": 34, "identity": "94.67%" }, { "cls_id": "homologset.agr.MGI:2136343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZL8-1", "uniprot_id": "D3ZZL8_RAT", "id": "D3ZZL8-1", "name": "Protein crumbs homolog 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNMKLKKTAYL-LALYLSSSLLICVKNSFCN--------------------------------KNNTRCLSNSCQNNSTCKRFPQ-DSSC-CLDTANDLDTD-CEDLKDPCLSSPCQGTATCVNIPGE-RSFLCQCPPGYSGLTCDTATNSCGGNLCQHGGTCHKDP-------------------------------------------------------------------------EHP---VCICPPGYAGRFCETD-----------------------------------------------------------------------------------------------------------HNECDSSPCHNG----------------------------------------AVCQDRINGYSCFCVPGYQGRHCDLEVDECVSDPCMNEAVCLNEIGRYTCVCPQEYSGVNCELEIDECGSQPCLHGATCRDALGGYFCDCAPGFLGDHCELNFNECESQPCLHGGLCVDGRNSYHCDCTGSG-FRGIHCESLIPLCWSKPCHNDATCEDTVDSYICHCWPGYTGALCETDINECSSNPCQFGGECAELSSQDLYGN------TAGLPSSFSYLGASGYVCICLPGFTGRHCEEDIDECLPNPCLNGGTCQNLPGNYTCHCP--------------------------------FDDTSRTFYGGEDCSEILLGCTHHQCLNNGKCIPHFQ-NGQHEFTCQCPSGYAGPLCETVTTLSFESNGFLWVTSGSHTSMGSECNISLKFQTVQPNALLLVRGNKDMSVKLELLDGCVHLSIEVW---NQSKVLLYISHNTSDGEWHLVEVTFAETITLALNGSSCK--EKCTTKSSVSIENHQSICALQNSFLGGLPMGTASDSMSVLNIYNVPSTPSFVGCLQDIRFDLNHITLES----ISSGLSSNVKAGCLRKDWCESQPCQNRGRCINLWQGYRCECDRPYAGSNCLKEYVAGRFGQDDSTGYAAFKVNDNFG-----QNFNLSMFVRTRQPLGFLLTLGNS---------TYQYVCVWLEHGSLALKTPGS----PKLVANFFLSDGNAHLISLRIKPNEIELYQSSQNLGFMSVPAWTIQRGDVIFIGGLPDR-----------------------------EKTEAYGGFLKGCIQDVRLNSQ----NLEFFPNSTNSAQHDP--------VLVNVTQGCPGDNVCKSNPCHNGGVCHSLWDDFSCSCPTNTSGRACDEVQWCQLSPCPPIAECQLVPQGFECIANAAFSGLSSEILFR------------SNGNITRELTNITFGFRTQDTNAVILHAEKEPEFLNISIQDSRLLFQLRSG----NSFYTLHLTGSQLVNDGAWHRVTFSMIDPRAQTSLWQME-VDDQTPFVISAVATGNLN-FLKDNTDIYVGDQ-----------AVDNQKGLQGCLSTVQIGGLYLSYFESLHGFTSKPQEEQFLKVSTNVALTGCLPLSACHSSPCLHGGICEDSYSSYRCACLPGWSGAHCEINVDECSSSPCVHG-NCSDGVAAYHCRCEPGYTGGNCEAEVDTCKSHQCANGATCVSGAQGYSCLCLGNFTGRFCRH----------------------------------SRLPSTVCGNEKTNFT-CYNGGSCSVFQEDWKCVCRPGFTGEWCEENINECASDPCINGGLCRDLVNRFQCICD-VAFAGERCELDL-ADDRLVGIITAVG-------------------------------------------------------------------------------------SGTLVLLFILLLAAIVSLIASNKRATQGTYSPSGQEKAGPRVEMWSRMPPPALERLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHS2-1", "uniprot_id": "CRUM1_MOUSE", "id": "Q8VHS2-1", "name": "Protein crumbs homolog 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLKRTAYL-LFLYLSSSLLICIKNSFCN--------------------------------KNNTRCLSGPCQNNSTCKHFPQ-DNNC-CLDTANNLDKD-CEDLKDPCFSSPCQGIATCVKIPGE-GNFLCQCPPGYSGLNCETATNSCGGNLCQHGGTCRKDP-------------------------------------------------------------------------EHP---VCICPPGYAGRFCETD-----------------------------------------------------------------------------------------------------------HNECASSPCHNG----------------------------------------AMCQDGINGYSCFCVPGYQGRHCDLEVDECVSDPCKNEAVCLNEIGRYTCVCPQEFSGVNCELEIDECRSQPCLHGATCQDAPGGYSCDCAPGFLGEHCELSVNECESQPCLHGGLCVDGRNSYHCDCTGSG-FTGMHCESLIPLCWSKPCHNDATCEDTVDSYICHCRPGYTGALCETDINECSSNPCQFWGECVELSSEGLYGN------TAGLPSSFSYVGASGYVCICQPGFTGIHCEEDVDECLLHPCLNGGTCENLPGNYACHCP--------------------------------FDDTSRTFYGGENCSEILLGCTHHQCLNNGKCIPHFQ-NGQHGFTCQCLSGYAGPLCETVTTLSFGSNGFLWVTSGSHTGIGPECNISLRFHTVQPNALLLIRGNKDVSMKLELLNGCVHLSIEVW---NQLKVLLSISHNTSDGEWHFVEVTIAETLTLALVGGSCK--EKCTTKSSVPVENHQSICALQDSFLGGLPMGTANNSVSVLNIYNVPSTPSFVGCLQDIRFDLNHITLEN----VSSGLSSNVKAGCLGKDWCESQPCQNRGRCINLWQGYQCECDRPYTGSNCLKEYVAGRFGQDDSTGYAAFSVNDNYG-----QNFSLSMFVRTRQPLGLLLALENS---------TYQYVSVWLEHGSLALQTPGS----PKFMVNFFLSDGNVHLISLRIKPNEIELYQSSQNLGFISVPTWTIRRGDVIFIGGLPDR-----------------------------EKTEVYGGFFKGCVQDVRLNSQ----TLEFFPNSTNNAYDDP--------ILVNVTQGCPGDNTCKSNPCHNGGVCHSLWDDFSCSCPTNTAGRACEQVQWCQLSPCPPTAECQLLPQGFECIANAVFSGLSREILFR------------SNGNITRELTNITFAFRTHDTNVMILHAEKEPEFLNISIQDARLFFQLRSG----NSFYTLHLMGSQLVNDGTWHQVTFSMIDPVAQTSRWQME-VNDQTPFVISEVATGSLN-FLKDNTDIYVGDQ-----------SVDNPKGLQGCLSTIEIGGIYLSYFENLHGFPGKPQEEQFLKVSTNMVLTGCLPSNACHSSPCLHGGNCEDSYSSYRCACLSGWSGTHCEINIDECFSSPCIHG-NCSDGVAAYHCRCEPGYTGVNCEVDVDNCKSHQCANGATCVPEAHGYSCLCFGNFTGRFCRH----------------------------------SRLPSTVCGNEKRNFT-CYNGGSCSMFQEDWQCMCWPGFTGEWCEEDINECASDPCINGGLCRDLVNRFLCICD-VAFAGERCELDL-ADDRLLGIFTAVG-------------------------------------------------------------------------------------SGTLALFFILLLAGVASLIASNKRATQGTYSPSGQEKAGPRVEMWIRMPPPALERLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82279-1", "uniprot_id": "CRUM1_HUMAN", "id": "P82279-1", "name": "Protein crumbs homolog 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALKNINYL-LIFYLSFSLLIYIKNSFCN--------------------------------KNNTRCLSNSCQNNSTCKDFSK-DNDCSCSDTANNLDKD-CDNMKDPCFSNPCQGSATCVNTPGE-RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDP-------------------------------------------------------------------------IYP---VCICPAGYAGRFCEID-----------------------------------------------------------------------------------------------------------HDECASSPCQNG----------------------------------------AVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG-FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR------ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--------------------------------FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQ-DGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQVN---NQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCK--EKCIAKAPTPLESDQSICAFQNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLEN----ISSGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESYG-----DTISLSMFVRTLQPSGLLLALENS---------TYQYIRVWLERGRLAMLTPNS----PKLVVKFVLNDGNVHLISLKIKPYKIELYQSSQNLGFISASTWKIEKGDVIYIGGLPDK-----------------------------QETELNGGFFKGCIQDVRLNNQ----NLEFFPNPTNNASLNP--------VLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFR------------SNGNITRELTNITFGFRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQSG----NSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQME-VDNETPFVTSTIATGSLN-FLKDNTDIYVGDR-----------AIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ----------------------------------SRLPSTVCGNEKTNLT-CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL-ADDLISDIFTTIG-------------------------------------------------------------------------------------SVTVALLLILLLAIVASVVTSNKRATQGTYSPSRQEKEGSRVEMWNLMPPPAMERLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TEP1-1", "uniprot_id": "A0AB32TEP1_DANRE", "id": "A0AB32TEP1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDMDLAVWGSVWLRLVACVLFVLLQWTESVTLL--------------------------------KTSTLCLDNPCQHQSECREALS-DFLCQCQTTVPVFPSTRCDSSSTFCQLSICQGNVTCQPTGAHPGELVCQCDSGLLGQDCLSSAQLCAQGHCGDSAHCLAVR-------------------------------------------------------------------------DQSPGYACICQEGYTGRSCEKE-----------------------------------------------------------------------------------------------------------VDHCSPNPCRNR----------------------------------------AICRSRRNGPTCFCVPGFQGQLCEIEVNECVSRPCRNGATCVDKIGHYICLCRPGYMGSSCELEIDECQSQPCLHGASCHDHINGFTCTCLAGFQGESCEINIDECRDQPCQNGALCVDEINSYRCDCSQTANFTGVDCEIPPPPCWSQPCLNSALCENQQENYTCNCWPGFEGRNCEVDVSECESNPCVNEGICMELSWKTLYGT------EPLFTARYNPRLASGFICKCPPGFSGALCEQNTTACTTSPCHNGATCEDFLGSYKCICP--------------------------------SESQDGVLYGGRNCSEPLTGCEGHECQNGASCIPFLS-EGVHGYSCICQPGYTGSYCQTLTVFSFETSRAFLHLQTPLLGAETYFNITLSFRTVLENTVLFQRGSGGVTLSLEIQETHLILDLKTDPQPNATSWTLMLPQVVSDGEWHTVEAVLGEGTLLLQLLEPCQGGQNCGTTAQVKIGALELESALLSTFVGGLDEGGSSR--------------SFIGCMRDLLVDSQLMIPED----WLSSSAVNVVQGCSHHDRCLSGPCENHGECVNLWQGYQCKCLRPYVGQNCDEEYITARFAQQDSTSYAVFTINDEPDS----ETLHLSMFLRTRKDSGLLVLLANS---------TSDYLQMWLEKGKLTVQVNNL----KTVTGERVLNDGERHFVSVTIEDGMMTLQDSDHEFEATYVQPVSIQFGDTINVGGLFDV-----------------------------QALTAFGGHFKGCLQDLQLNEK----KLEFFPIDTSAMSYKPD-------RVVKVTAGCTSDDTCSKNPCQNGGICFSSWDDFTCNCPPNTSGQHCEEVSWCDLNPCPPQAICRALNQGYECISNVTFQEN-TTLVYQ------------GNGLISRHLTSIVFNIRTRKRNAIVLHAESGSEFVTVSLQDGFLVLELLSGPTTSSSLSPVTLHSPRVVADGEWHVIELLMATPGSNSSHWIMVPLDEKDEPTKSDSMTGNLD-FLRESVYIMLGGL-----------GPDSGSNLIGCLSNVEIGGIVLPYYGQTEVRFPRTQEEMFNKISEEPVQTGCFGEVVCEPNPCLHGGICDDHFNLFHCFCLPGWGGDHCELNTNTCASNPCRHG-YCSVQDLTYNCTCEDGYTGTNCEMKVDACAGHRCANGATCLRGFNMYSCLCTDKFTGPLCNIQIEEVPWYVVVRN-------------------IPPKLPVSICGDEQQNYT-CFNGGNCS--DTNMPCDCHPGFSGHWCELELDECRSNPCKNGGYCQNMVNRFQCVCE-MTFAGETCEVDLNAESVTSQLLLSIS-------------------------------------------------------------------------------------LVCVVLLLVVFGVTTALVIALNRRATRGTYSPSRQEKEGSRVEMWNIVQPPPMERLI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10040-1", "uniprot_id": "CRB_DROME", "id": "P10040-1", "name": "Protein crumbs", "aln": "MAKIANASLSQQQKQRQAETATTTTTTVAASVETATTTARSRDRTKSAAQITSHLLKRAISVYSSPQWIPLFILIYLATDVASVAVPTKEAYFNGSTYLRLTTPMPIWDHSAISFRSCRGGEILAQQYNKNSIVISVLNDFLQISLAGPAVHGPNNRLDVKLPYQLLDNRWHTLQFKYEYGNLYLHVDRAASIFANSTYNSQFLTNQDIGYKDAILILGNSFSGCLLDGPGLQFVNNSTVQNVVFGHCPLTPGPCSDHDLFTRLPDNFCLNDPCMGHGTCSSSPEGYECRCTARYSGKNCQKDNGSPCAKNPCENGGSCLENSRGDYQCFCDPNHSGQHCETEVNIHPLCQTNPCLNNGACVVIGGS-GALTCECPKGYAGARCEVDTDECASQPCQNNGSCIDRINGFSCDCSGTGYTGAFCQTNVDECDKNPCLNGGRCFDTYGWYTCQCLDGWGGEICDRPMTCQTQQCLNGGTCLDKPIGFQCLCPPEYTGELCQIAPSCAQQCPIDSECVGGKCVCKPGSSGYNCQTSTGDGASALALTPINCNATNGKCLNGGTCSMNGTHCYCAVGYSGDRCEKAENCSPLNCQEPMVCVQNQCLCPENKVCNQCATQPCQNGGECVDLPNGDYECKCTRGWTGRTCGNDVDECTLHPKICGNGICKNEKGSYKCYCTPGFTGVHCDSDVDECLSFPCLNGATCHNKINAYECVCQPGYEGENCEVDIDECGSNPCSNGSTCIDRINNFTCNCIPGMTGRICDIDIDDCVGDPCLNGGQCIDQLGGFRCDCSGTG-YEGENCELNIDECLSNPCTNGAKCLDRVKDYFCDCHNGYKGKNCEQDINECESNPCQYNGNCLERSNITLYQMSRITDLPKVFSQPFSFENASGYECVCVPGIIGKNCEININECDSNPCSKHGNCNDGIGTYTCECEPGFEGTHCEINIDECDRYNPCQRGTCYDQIDDYDCDCDANYGGKNCSVLLKGCDQNPCLNGGACLPYLINEVTHLYNCTCENGFQGDKCEKTTTLSMVATSLISVTTE----REEGYDINLQFRTTLPNGVLAFGTTGEKNEPVSYILELINGRLNLHSSLLNKWEGVFIGSKLNDSNWHKVFVAINTSHLVLSAN-----DEQAIFPVGSYETANNSQPSFPRTYLGGTIPNLKSYLR-----HLTHQPSAFVGCMQDIMVNGKWIFPDEQDANISYTKLENVQSGCPRTEQCKPNPCHSNGECTDLWHTFACHCPRPFFGHTCQHNMTAATFGHENTTHSAVIVETTDVARRAIRSILDISMFIRTREPTGQVFYLGTDPRKAPTKNIGDSYVAAKLHGGELLVKMQFSGTPEAYTVGGQKLDNGYNHLIEVVRNQTLVQVKLNGTEYFRKTLSTTGLLDAQVLYLGGPAPTRESLLGATTEPGIIPVPGAGIPIEDTTVPKEADDSRDYFKGIIQDVKVSNGSLNLIVEMYSLNVTDVQVNAKPLGAVTIDRASVLPGEVSDDLCRKNPCLHNAECRNTWNDYTCKCPNGYKGKNCQEIEFCQHVTCPGQSLCQNLDDGYECVTNTTFTGQERSPLAFFYFQEQQSDDIVSEASPKQTLKPVIDIAFRTRAGGTLLYIDNVDGFFEIGVNGGRVTITWKLS----ALHFGESARFEKENTDGEWSRIYLRAHNSKLEGGWKGWESMVDPTPAFSTDIDQAAFQSLIATSTQVYLGGMPESRQARGSTLSAQQGSQFKGCVGEARVGDLLLPYFSMAELYSRTNVSVQQKAQFRLNATRPEEGCILCFQSDCKNDGFCQSPSDEYACTCQPGFEGDDCGTDIDECLNTECLNNGTCINQVAAFFCQCQPGFEGQHCEQNIDECADQPCHNGGNCTDLIASYVCDCPEDYMGPQCDVLKQMTCENEPCRNGSTCQNGFNASTGNNFTCTCVPGFEGPLCDIPFCEITPCDNGGLCLTTGAVPMCKCSLGYTGRLCEQDINECESNPCQNGGQCKDLVGRYECDCQGTGFEGIRCENDIDECNMEGDYCGGLGRCFNKPGSFQCICQKPYCGAYCNFTDPCNATDLCSNGGRCVESCGAKPDYYCECPEGFAGKNCTAPITAKEDGPSTTDIAIIVIPVVVVLLLIAGALLGTFLVMARNKRATRGTYSPSAQEYCNPRLEMDNVLKPPPEERLI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *: . ...: * ...*:: . * * * * . . * . * . :* . : *:* * * * *. * ... * . *:* *:*. *: :.* ..**:* .:*:. .. .*:*.**: * *: :*:** * ** * *.* ::*. * *:* : * .**::**** *:** :*::* * . : * * .*: * *::. ::* .:** :*. *:* . : *:*: :. : * .** * *:** *.* * : ..* *.* *: * ** *:.**.**** * * * * * :. :. ***: * * **: * ** : * ** : ..*:: *.* * * : . ***.:** * ** : * *.. *:*.: : * :.* * *: * *: *.:*: : :* * *:*. :* . :. : :: : : .*.:** * . : : ::. : :: :::** . . :*:**::*: .: : : :. ** ** : * . **...*.* :** : *.* **: * .* .: :. *.::::* . : . . : :***:** : * :. * .. .*: *. * * : *.:* *::.: : : : .. : . : .:.: :** : ..:** :**:::.. :*::. .. .. ..* * .*: * .*** :.. * . *:*::*.** *: *:::.:* .** : *: : :*:**::*..* : .:. .: *. : . :*: :. *. :.::.. : : . : ** * : : . : . : : : . :: :: .. : :*. . :. . : **:. .:*.: *.*: . . . * . * :.* *:. . : * * *: * .* : : * .. * :. * :: * *: *: * :** .:* * .: * **..* * * * .: * * . : .:*. : * * *** * * * *::*. ** :::** *:** *** *::::.:: * *: * * ** *: . :. : *:: ::: *:***:****** ** ..*:** : **. ****", "identical_positions": 312, "similar_positions": 391, "identity": "14.4%" }, { "cls_id": "homologset.agr.MGI:2136348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5Y7-1", "uniprot_id": "LYVE1_HUMAN", "id": "Q9Y5Y7-1", "name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "aln": "---MARCFSLVLLLTSIWTTRLLVQGSLRAEELSIQVSCRIMGITLVSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFETCSYGWVGDGFVVISRISPNPKCGKNGVGVLIWKVPVSRQFAAYCYNSSDTWTNSCIPEIITTKDPIFNTQTATQTTEFIVSDSTYSVASPYSTIPAPTTTPPAPASTSIPRRKKLICVTEVFMETSTMSTETEPFVENKAAFKNEAAGFGGVPTALLVLALLFFGAAAGLGFCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKANDSNPNEESKKTDKNPEESKSPSKTTVRCLEAEV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BHC0-1", "uniprot_id": "LYVE1_MOUSE", "id": "Q8BHC0-1", "name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "aln": "---MLQHTSLVLLLASIWTTRHPVQGADLVQDLSIST-CRIMGVALVGRNKNPQMNFTEANEACKMLGLTLASRDQVESAQKSGFETCSYGWVGEQFSVIPRIFSNPRCGKNGKGVLIWNAPSSQKFKAYCHNSSDTWVNSCIPEIVTTFYPVLDTQTP--ATEFSVSSSAYLASSPDSTTPVSATTR-APPLTSMARKTKKICITEVYTEPITMATETEAFVASGAAFKNEAAGFGGVPTALLVLALLFFGAAAVLAVCYVKRYVKAFPFTTKNQQKEMIETKVVKEEKADDVNANEESKKTIKNPEEAKSPPKTTVRCLEAEV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R2G7-1", "uniprot_id": "F1R2G7_DANRE", "id": "F1R2G7-1", "name": "", "aln": "MTRVCMGMMMMMIKMVLFSGLFMSGLAFDMQLVKVHPKQAISGVSEASIGNQYALNASSARDLCEHLGLTIANKAQLAEAQKHGLETCRFGWIDEQIAVVPRVKVNPNCGNGKTGVVVWRADPSKQFDVFCFNVTDFETQASIKVHQMTTGKPMTTRSSVAPTAGVHLRGSPLSKLPSHWSSVPRSASAGPSVVHRADAKHLALSSGSTEAVPAALLITVTFAVMIAVFL--ALYYVRTKRPCKAQCDVEQQKEYIETEVWEHHTKEDLQKTQEEQVEDKNQEEQMEEKNQEELDENHQEEQMEERRQEEHMKKNQEEQVEENDSSSAEQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::: ::: : : :.: * *:: .. : :* :.*.: *. ***::*.: *: * * .:*** :**:.: : *:.*: **.**:. **::*.. *::* .:*.* :* .::.* * : *::. .* .: * ... :: .*. . . .: : : * .*. *.* * : . . . . : : :: : : * ::* :: : : ::*:: :: : *.:.:: :. :* : : : * : ", "identical_positions": 48, "similar_positions": 115, "identity": "14.55%" }, { "cls_id": "homologset.agr.MGI:2136381", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60587-1", "uniprot_id": "ECHB_RAT", "id": "Q60587-1", "name": "Trifunctional enzyme subunit beta, mitochondrial", "aln": "MTTILTSTFRNLSTTSKWALRFSVRPLSCSSQVQSAPAVQTKSKKTLAKPNLKNIVVVEGVRIPFLLSGTSYKDLMPHDLARAALSGLLYRTNIPKDVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRHSRNMRKMMLDLNKAKTLAQRLSLLTKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFAVSRMEQDKYALRSHSLAKKAQDEGHLSDIVPFKVPGKDTVS-KDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMSEDRALAMGYKPKAYLRDFIYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAQNYMGRKTKVGAPPLEKFNIWGGSLSLGHPFGATGCRLVMAAANRLRKDGGQYALVAACAAGGQGHAMIVEAYPK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JY0-1", "uniprot_id": "ECHB_MOUSE", "id": "Q99JY0-1", "name": "Trifunctional enzyme subunit beta, mitochondrial", "aln": "MTTILTSTFRNLSTTSKWALRSSIRPLSCSSQLHSAPAVQTKSKKTLAKPNMKNIVVVEGVRIPFLLSGTSYKDLMPHDLARAALSGLLHRTNIPKDVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRHSRNMRKMMLDLNKAKTLGQRLSLLSKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFAVSRMEQDEYALRSHSLAKKAQDEGHLSDIVPFKVPGKDTVT-KDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMSEDRALAMGYKPKAYLRDFIYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAQNYMGRKTKVGSPPLEKFNIWGGSLSLGHPFGATGCRLVMAAANRLRKDGGQYALVAACAAGGQGHAMIVEAYPK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55084-1", "uniprot_id": "ECHB_HUMAN", "id": "P55084-1", "name": "Trifunctional enzyme subunit beta, mitochondrial", "aln": "-MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVT-KDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1H8-1", "uniprot_id": "Q9W1H8_DROME", "id": "Q9W1H8-1", "name": "acetyl-CoA C-acyltransferase", "aln": "--MSLQNVCR---KGNAFNLLNVARKVQCRALSAAVANPQPKQK------NSQNIVLVDGVRTPFLTSGTTYSKLMPHELARHSLLSLLQKNRLDKELIDYIVYGSVIQEVKTSNIAREAALAAGFSNKTPAHTVTMACISSNAAITTGMGLIATNTYDVIVAGGVEFMSDVPIRHSRKMRSLLLKANKAKTLGQRLALLSTFRPDFLAPELPAVAEFSSGETMGHSADRLASAFNVSRSEQDEYALRSHTLAKEAQEKGYFTDLVPFKVSGVDQIVDKDNGIRVSSPESLAKLRPAFVKPYGTVTAANASFLTDGASACIIMTEEKAKQLGLKPKAYLRDFLFVSQDPVNQLLLGPAYGIPKLLKKAGLTLKDIDSWEIHEAFAGQIVANLKALDSDWFCKTYLGLNEKVGTPDLSKWNNWGGSLSIGHPFAATGVRLCMHTANRLVREDGKLGVVAACAAGGQGVAMLIERYPGATAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . : * * :.* : :.. *.* * * :*:*:*:*** *** ***:*..****:*** :* .** :. : *:::***::*:*********:******.****:*************:* *:**.:****:. **:******:**********:**.::*. ****::.***:*::.** :**:******:***:.***********:** *** ***:******:***:**::* ::*:*****.* * : ****** ** *.:***:***:**********:********* :**:*::* :* *********::***** :******:*. **:*:*****::***::*:****:***:**:**:*****.:.*:* : *** * *.*:* ******:****.*** ** * :**** ::.*: .:********** **::* ** ", "identical_positions": 290, "similar_positions": 113, "identity": "60.42%" }, { "cls_id": "homologset.agr.MGI:2136388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924H9-1", "uniprot_id": "DQX1_MOUSE", "id": "Q924H9-1", "name": "ATP-dependent RNA helicase homolog DQX1", "aln": "------------------MASG---LAEES---ELSPGES---------------------------ELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGDPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWSVLILDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVVVTDPALEPKFQAFWGNSPIVRVPREPGGDPTLAYKDTVPTDLVEAACQAVLELCQQEEAPGDVLVYLPSEEEISLCCESLSG-EMGTLAVPGPPPR-------VLPLHPGCAQAIQTVYEDTDVSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAESQVLRPISKCQAEARLLRAKGFPPGSCLRLYSKSTLELEAPPLPHPKVCEENLSSLVLLLMRKQIAEPGECHFLDRPAPEALMRALEDLDYLAALNDDGELSDLGVILSEFPLPPELAKALLASCEFNCVDEMLTLAAMLTAAPGFTRPPLSAGEAALRR-ALEHADGDHSSLIQVYEAFVQSGADEA----WCQARGLNWESLCQARKLRAELVELMQRIELPLSQPAFGSEQNRRDLQKALLSGYFLKVARDTDGTGNYLLLTHKHVAQLSPYCSYRNRRTPAQPPTWVLYHSFSISKDNCLCIVSEIQPEMLVELAPPYF-LSNLPPSESRDLLNQLREGTAEPPAAATETSSPQEYGDGCVLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A474-1", "uniprot_id": "D4A474_RAT", "id": "D4A474-1", "name": "ATP-dependent RNA helicase homolog DQX1", "aln": "------------------MASG---LAEES---EPSPGES---------------------------ELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWSVLVLDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVIVTDSALEPKFQAFWGNSPTVHVPREPGENPTLTYKDTVPADLVEAACQAVLELCQREEAPGDVLVYLPSEEKWALVFLSLSKREMGMLAVPGPLPR-------VLPLHPGCGQAIQTVYEDTDVSVRKIVVTHWLADFSFSLPFIQHVIDSGLELRSVYNPRIRAESQVLRRISKCQAEARLLRARGFPPGTCLRLYSKSTLDLEAPPLPHPKVCEENLSSLVLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLPPELAKALLASCEFNCVDEMLTLAAMLTAAPGFTRPPLCAGEAALRR-GLEHADGDHSSLIQVYEAFVQSGADET----WCQARGLSWEALCQARKLRAELLELMQRIELPLSLPAFGSEQNRRDLQKALLSGYFLKVARDTDGTGNYLLLTHKHVAQLSPYCVYRNRRTPAQPPTWVLYHRFSISKDNCLCTVSEIQPEMLVELAPPYF-LSNLPPSESRDLLNQLREG-TEPSAAVTETASPQEYGDGCVLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TE96-1", "uniprot_id": "DQX1_HUMAN", "id": "Q8TE96-1", "name": "ATP-dependent RNA helicase homolog DQX1", "aln": "------------------MTSQPLRLAEEY---GPSPGES---------------------------ELAVNPFDGLPFSSRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWGNPPIVHIPREPGERPSPIYWDTIPPDRVEAACQAVLELCR-KELPGDVLVFLPSEEEISLCCESLSR-EVESLLLQGLPPR-------VLPLHPDCGRAVQAVYEDMDA--RKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEEAALRR-ALEHTDGDHSSLIQVYEAFIQSGADEA----WCQARGLNWAALCQAHKLRGELLELMQRIELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSSYCCYRSRRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQMLVELAPPYF-LSNLPPSESRDLLNQLREG-MADSTAGSKSSSAQEFRDPCVLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53131-1", "uniprot_id": "PRP43_YEAST", "id": "P53131-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43", "aln": "MGSKRRFSSEHPDPVETSIPEQAAEIAEELSKQHPLPSEEPLVHHDAGEFKGLQRHHTSAEEAQKLEDGKINPFTGREFTPKYVDILKIRRELPVHAQRDEFLKLYQNN--QIMVFVGETGSGKTTQIPQFVLFDEMP-HLENTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRYSCIILDEAHERTLATDILMGLLKQVVKRRP--DLKIIIMSATLDAEKFQRYFNDAPLLAVPGRTYP-VELYYTPEFQRDYLDSAIRTVLQIHATEEAG-DILLFLTGEDEIEDAVRKISLEGDQLVREEGCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELIEQSYPEILRSNLSSTVLELKKLGIDDLVHFDFMDPPAPETMMRALEELNYLACLDDEGNLTPLGRLASQFPLDPMLAVMLIGSFEFQCSQEILTIVAMLSVPNVFIRPTKDKKRADDAKNIFAHPDGDHITLLNVYHAFKSDEAYEYGIHKWCRDHYLNYRSLSAADNIRSQLERLMNRYNLELNTTDYESPKYFDNIRKALASGFFMQVAKKRSGAKGYITVKDNQDVLIHPSTVLG------HDAEWVIYNEFVLTSKNYIRTVTSVRPEWLIEIAPAYYDLSNFQKGDVKLSLERIKEKVDRLNELKQGKNKKKSKHSKK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :*** *.*. : :*** * *:. * ::*: *: **: * * **: :.. :::. *:.****:*****: :. ::. **: *** :** *:* ***:***:.**.*:**** *: *. :*:*:: * ::*:*. . :. . :. ::****:**::*:* * ***::. .. * :::::: . *:: ::.:.* : :* .. * . * :::* ::**:: :* *:*::*..*:: .:* : * * ** * : .. . **:*:: :*: *::: * :*:*.*:. :.*******.* :: ***..*: * ** **.*: **.:. :: * . *.: ..**** ** * : * : . .*:* ****::*:***:*:***.*:*:*:*: ** : *:*** * ** *:.* **:* :*:**:.***:.. * **. .* : : *.**** :*::**.** .. * * **: : *.: :*. * ::*.:* .**:* :* *. . : * : :::*** **:*::**:. .*: .*: :..:: . : . : . **:*: * ::..* : *:.::*: *:*:**.*: ***: .: : *::::* . . :. . ", "identical_positions": 223, "similar_positions": 247, "identity": "28.48%" }, { "cls_id": "homologset.agr.MGI:2136405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIK0-1", "uniprot_id": "D3ZIK0_RAT", "id": "D3ZIK0-1", "name": "heparosan-N-sulfate-glucuronate 5-epimerase", "aln": "-MRCLAARVNYKTLIIICALFTLVTVLLWNKCSS-DKAIQFPRHLSSGFRVDGLEKRSAASESNHYANHIAKQQSEEAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIRGRRE--GNEVFLPFTWVEKYFDVYGKVVQYDG-YDRFEFSHSYSKVYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDRNIRPNEWTVPKGCFMASVADKSRSTNVKQFIAPEAGEG-VSLQLGNTKDFIISFDLKFLTNGS-VSVVLETTDKNQLFTVHYVSNTQLIAFKDRDIYYGIG--PRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQD-EKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLT-KDYVFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPS3-1", "uniprot_id": "GLCE_MOUSE", "id": "Q9EPS3-1", "name": "D-glucuronyl C5-epimerase", "aln": "-MRCLAARVNYKTLIIICALFTLVTVLLWNKCSS-DKAIQFPRHLSSGFRVDGLEKRSAASESNHYANHIAKQQSEEAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIKGRRE--GNEVFLPFTWVEKYFDVYGKVVQYDG-YDRFEFSHSYSKVYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDRNIRPNEWTVPKGCFMASVADKSRSTNVKQFIAPETSEG-VSLQLGNTKDFIISFDLKLLTNGS-VSVVLETTEKNQLFTVHYVSNTQLIAFRDRDIYYGIG--PRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQD-EKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLT-KDYVFLSSALRATAPYKFPSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGETLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94923-1", "uniprot_id": "GLCE_HUMAN", "id": "O94923-1", "name": "D-glucuronyl C5-epimerase", "aln": "-MRCLAARVNYKTLIIICALFTLVTVLLWNKCSS-DKAIQFPRRSSSGFRVDGFEKRAAASESNNYMNHVAKQQSEEAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCLINDEHTIKGRRE--GNEVFLPFTWVEKYFDVYGKVVQYDG-YDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNK-PNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEG-VSLQLGNTKDFIISFDLKFLTNGS-VSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIG--PRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQD-EKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLT-KDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QR43-1", "uniprot_id": "GLCEB_DANRE", "id": "F1QR43-1", "name": "D-glucuronyl C5-epimerase B", "aln": "MMRCLAARVHYKTLIVICALLSLLTVLLWNKCTS-EKALRF------------LPRHPQPPPSPKIDSHPQQPQ-----PPE---PPPVVG-----------GVRYEEIDCLINDDATIKGRRE--GSEVYMPFSWMEKYFEVYGKVVQYDG-YDRFEFSHSYSKVYAQREQYHPNGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYAIQIAQYGLSHYSKNLTERPPHVEVYDTAEERDSRS--SAWTVPKGCSLTRVYDKTRATSVRQFSAPENSEG-VSLPLGNTKDFIISFDLKFTSNGS-VSVILETTEKGPPFVIHYVTTTQLILLKDRDITYGIG--PRTTWTTVTRDLLTDLRKGIGLSNTKAVKATKTMPRRVVKLVVHGTGTIDNITISTTSHMAAFYAASDWLVRNQD-ERGGWPIMVTRKLGEGFRALEPGWYSAMAQGQAMSTLVRAYLMT-KDDTYLKAALRATGPFKLPSEQHGVKAVFMNKYDWYEEYPTIPSSFVLNGFIYSLIGLFDLAQTAGEKLGRDAGQLYSKGMESLKVMLPLYDTGSGTIYDLRHFILGTAPNLARWDYHTTHINQLQLLGTIDNSPIFRDSVKRWKSYLKGGRAKHN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5A6-1", "uniprot_id": "A0ACD6B5A6_DANRE", "id": "A0ACD6B5A6-1", "name": "heparosan-N-sulfate-glucuronate 5-epimerase", "aln": "-MRCLVARINHKTLIVICAVFALITILLWNKCSS-DKDLPSPVR----------PLEFAAPTPEKEEENEGQAP----------EAPPGSR-----------EVAYEQIDCLINEDVLIKGRRE--GGEVYLPFSWVEKYFDVYGRLVQYDG-MERFEFSHSYSRVYAQREPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPISTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPDIKIYGMLEEKEGGS--SPWDVPKGCTLSKIQDQGRSGFVHHFVTAENSEG-VSLVLDNAKDFVLTFDVKFISNGS-VSVVLETTEKGPPYIIHYITSPLLLSFKDKEVIYGIG--PRATWSTVSRDLMTDLRKGVGLSNTKVVKATKIMPRRVVQLVLKGSGFISNITVSSTAHMAAFFAASDWLLHNQD-EHGGWPIKVTRKLGEGFKSLEPGWYSAMAQGQAMSTLVRAYLVT-HNPSYLGAAIRATSPFKRTPEQHGVKATFMNKFDWYEEYPTTPSSFVLNGFIYSLIGLYDVAETAGNKLGREAGILFSQGLESLKAMLPLFDTGSGTVYDLRHFTLGVAPNLARWDYHTTHINQLQLLASIDGAPIFRDYVKRWKTYLKGGRAKHN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6M8-1", "uniprot_id": "A1Z6M8_DROME", "id": "A1Z6M8-1", "name": "heparosan-N-sulfate-glucuronate 5-epimerase", "aln": "MSKYLSSQRDALSAPALPVSRENREPPKFQGVKQREPLVFFIMRLNLKAVLLVLTVAVVVITLGVYMRCAAFSFSPDFVRPLDRSARQSSSGGE--------ATALHDIECSINQEYTVHCKRDENANEVYVPFSFLRNYFDVSGAVSTNSNEVAKFNWVHSTAKVNLPRGKYDARGVYMYFENYNVEVRDRVKCISAAEGVPVSTQWEKRGYFYPTQIAQFALSHYSKNLTEPAPRVRVLE---DGDGNQ--MEWSTPKTSNMTRIWHHKFNTSVVQFETAPGYEGVISIALNQTLDLLLSVDLLLVTNSSSLMITVQNRDTRHNYSLHYIPADLLLSVQDTNIYYGLGGSALNKWRHITRDLHIDLQKGI-MGDKRSPLKIRRSDLEVISIGFLGLGFFDNITLSTSDHLAHFYDAAEWFVHNQDPKTGGWTNPVRRSL-NGFAELRPGWISAMGQGHAISVLARAYWHSGGDERYLRAAAAGLQPYRVYSRDGGVLAQFMDKFYWYEEYPTTPPSYVLNGFIYSLLGLYDLNSTAPGKIAREAGKLFAQGMHSLKKMLLLFDTGSGTSYDLRHLSLGVAPNLARWDYHATHVNQLLLLATIDSDPLIAQTAERWKGYMFGRRAKHN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :: . : : . :: .. : : . .:*:* **:: :: :*: ..**::**:::.:**:* * : .. :*:: ** ::* * *.. **:* **.*************..****:**** :****. ****:.********** .* :.: : : * .** . :: : .: * :* :. ** :*: *.:: *::::.*: : :*.* : : ::. :. : :**:. *: .:: :: **:* . .* ::*** **:**: :.:.: : .*: : * * :.***:*:: *:* *: *::*:::*** : ***. * *.* :** *.*** ***.**:*:*.*.*** : : :* :* . *:: ..: ** * **:*. ******* *.*:*****:***:**:*: .** .:.::* *: :*:.*** ** *:****** *****: ** **********:**:*** **.:** *:: : .:*** *: * *****", "identical_positions": 213, "similar_positions": 177, "identity": "33.86%" }, { "cls_id": "homologset.agr.MGI:2136419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUM2-1", "uniprot_id": "SARM1_RAT", "id": "D3ZUM2-1", "name": "NAD(+) hydrolase SARM1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLTLLFSAYKLCRFFIMSGPRPGADRLTVPGPDRSGGTSPWWAAGGRGSREVSPGVGT---------------------------------EVQGALERSLPELQQALSEL---KQASAAQAVGAG-------LAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLS---KEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALANCALHGGQTVQRCMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVEHSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQSLVLLLDSSRLEAQCIGAFYLCAEAAIKSLQGKTKVFSDIGAIQSLKRLVSYSTNGTTSTLAKRALRLLGEEVPRRILPCVASWKEAEVQTWLQQIGFSQYCENFRDQQVDGDLLLRLTDEELQTDLGMKSSITRKRFFRELTELKTFASYATCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIRLGVHRTRILSAAREMLHSPLPCTGGKPSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVMAARNFVLVLSAGALDKCMQDHECKDWVHKEIVTALSCSKNIVPIIDG-FEWPEPQALPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQG------------------------------------------------------------------------------RPSQDSSAGSDTSLEGATSMGLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDS3-1", "uniprot_id": "SARM1_MOUSE", "id": "Q6PDS3-1", "name": "NAD(+) hydrolase SARM1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLTLLFSAYKLCRFFTMSGPRPGADRLTVPGPDRSGGASPWWAAGGRGSREVSPGVGT---------------------------------EVQGALERSLPELQQALSEL---KQASAARAVGAG-------LAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLA---KEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALANCALHGGQTVQRCMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVEHSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQSLVLLLDSSRLEAQCIGAFYLCAEAAIKSLQGKTKVFSDIGAIQSLKRLVSYSTNGTTSALAKRALRLLGEEVPRRILPCVASWKEAEVQTWLQQIGFSQYCENFREQQVDGDLLLRLTDEELQTDLGMKSSITRKRFFRELTELKTFASYATCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIRLGVHRTRILSAAREMLHSPLPCTGGKLSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVIAARNFVLVLSAGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDG-FEWPEPQALPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQG------------------------------------------------------------------------------RPSQDSSAGSDTSLEGATPMGLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6SZW1-1", "uniprot_id": "SARM1_HUMAN", "id": "Q6SZW1-1", "name": "NAD(+) hydrolase SARM1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLTLLLSAYKLCRFFAMSGPRPGAERLAVPGPDGGGGTGPWWAAGGRGPREVSPGAGT---------------------------------EVQDALERALPELQQALSAL---KQAGGARAVGAG-------LAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLA---KEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALGNCALHGGQAVQRRMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVERSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQRLVPLLDSNRLEAQCIGAFYLCAEAAIKSLQGKTKVFSDIGAIQSLKRLVSYSTNGTKSALAKRALRLLGEEVPRPILPSVPSWKEAEVQTWLQQIGFSKYCESFREQQVDGDLLLRLTEEELQTDLGMKSGITRKRFFRELTELKTFANYSTCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIHLGVHRARILTAAREMLHSPLPCTGGKPSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVMGARNFVLVLSPGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDG-FEWPEPQVLPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQG------------------------------------------------------------------------------RSSRDSSAGSDTSLEGAAPMGPT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QWA8-1", "uniprot_id": "SARM1_DANRE", "id": "F1QWA8-1", "name": "NAD(+) hydrolase SARM1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFLSLVVYLSKICRYLSMFS----SDRLTVPEYVSSRLHNRRTAPD---PRAVSPGIST---------------------------------DVQAVLDGSLPALRSAIRTLRSSKDTGDLEETRRA-------IAETFQLVEEAWVLPTVGRRVAEEICNRIRLDGGLELLLQLMQTPAVEITYESAKLLEQILVSENRDYVARMGLGVILNLT---REQEDAQLARSVSGILEHMFKHTEETSAQLITNGALDTILYWCRGTDPTVLRHCAVALSNCAMYGGHRCQRLMIEKQAAEWLFPLAFSKEDELIRFHACLAVAVLAANREMEKEVVKSGTLELVEPFIASLDPDEFARNMLDSADSMQGRTAADLQHLLPLLDGTRLEGKCIAAFYLCVETSIKSRQRNTKIFQEIGAVQSLKRIVMYSSNATVCSLAKRALKMMSEEVPRRILSSVPNWKSGEVQTWLQQIGFSAFSERFQELQVDGDLLLNITEQDLIQDLGMTSGLTRKRFLRDLRVLKTYANYSTCDPNNLADWLADADPRFRQYTYGLVQSGVDRNNIVHITDQQLLTDCHVENGIHRAKILSAARRPSKPCL--TDSQPKG--PDVFISYRRTTGSQLASLLKVHLQLRGFSVFIDVEKLEAGRFEEKLITSVQRARNFILVLSANALDKCMGDVAMKDWVHKEIVTALNGKKNIVPVTDN-FVWPDPTSLPEDMSTILKFNGIKWSHEYQEATIEKILRFLEG------------------------------------------------------------------------------CPSQEKPDGAKTDKKEPQKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6IDD9-1", "uniprot_id": "SARM1_DROME", "id": "Q6IDD9-1", "name": "NAD(+) hydrolase sarm1", "aln": "MKAAEIKRDLTNIQKSMSEINDLAKERITGGPGSISTTSASAITAPSTMSQTTTSRLAPKLTSAHPSIDDLRGLSRQDKITQLQKKIRASFENLVDHDDSNVIVTLPDDDDCPHNHFGSGLNLTHPTAAQLSASGLSGSSKTIDTIKFQEKSMKTESKTKVVTDGFSSEQATSNSAEMKRLQAGDIDYQESKGASAMRNRLEVDGVKTEENAAVIKEALSLRTGDITQQASNNVAASSITVQSENFSADKKAISQSQQSQTMTSNGIISQEKHVSSASQANYSMSHKGVSSTGSSMITSSSQMSAMNGQMLKLADLKLDDLKSLTAGSGQQEIEQTINKYSNMLTSIVSSLQEDERGGSAITVHDVGGKKSQYLEKINEVIRRAWAVPTHGHELGYSLCNSLRQSGGLDLLMKNCVKPDLQ--FSSAQLLEQCLTTENRKHVVDNGLDKVVNVACVCTKNSNMEHSRVGTGILEHLFKHSEGTCSDVIRLGGLDAVLFECRTSDLETLRHCASALANLSLYGGAENQEEMILRKVPMWLFPLAFHNDD-NIKYYACLAIAVLVANKEIEAEVLKSGCLDLVEPFVTSHDPSAFARSNLAHAH---GQSKHWLKRLVPVLSSNREEARNLAAFHFCMEAGIKREQGNTDIFREINAIEALKNVASCP-NAIASKFAAQALRLIGETVPHKLSQQVPLWSVEDVQEWVKQIGFNDYIDKFNESQVDGDLLLKLNQDNLRADIGIGNGILLKRFERELQNLKRMADYSSKDTAKMHQFLSEIGTDYCTYTYAMLNAGIDKCALPHVNEDMLMTECGIHNSIHRLRILNAVKN-LENSLPSSSEENMAKTLDVFVSYRRSNGSQLASLLKVHLQLRGFSVFIDVERLEAGKFDNGLLNSIRQAKNFVLVLTPDALHRCINDEDCKDWVHREIVAALNSNCNIIPIIDQQFDWPEVERLPEDMRSVAHFNGVNWIHDYQDACIDKLERFLRGEKNIDRIAAMVPGTPGSVSYQRMHSNDSDYQSGGAGAGSGAGTGGGGGGGVTGSVVDGLMVAANGSGQANHQANRYRQSPSPARQRGSTSQLSGYSRAPSKRSQILTPYRTQQAALLHKTGAGSASMQNMMPLAYLPPRRSSAAGLGHGSGSGMGSGYRSHSVDGLLDQAGSTPEQRIAAAAAKVTAGSTALTNASSTSTLQPEEEVTDAALNDSVTRRDKHTLSPPGNVQQHRKSRSLDHILSKQTLAELLPPSSELADGTQSMQNLAIPMTPQPQRRDTSSSSKSPTPERPPQPAMERVRERQSPEGVSATESEREDQPEECLRHGNQQRASASVHRGASLTSNKTSNSSLGSNFSAGGNNKTIFNRTMKKVRSLIKKP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 248, "similar_positions": 242, "identity": "18.13%" }, { "cls_id": "homologset.agr.MGI:2136446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85118-1", "uniprot_id": "NT8F2_RAT", "id": "P85118-1", "name": "N-acetyltransferase family 8 member 2", "aln": "MAPYHIRQFQDRDHRRVLDLFSRGMEEHVPAAFYHVLTLPHSLLLFPGVPVTIILVSGSWLLATVYSFLFLLCLRLIFWVSCRNYVAKCLQADLADITKSYLNAHGS-FWVAESGGQVVGIVAALPVKEPPSGRKQLQLFRLSVSSQHRGQGIAKALVRIVLQFARDQGYTDVVLVTGNMQYSAISLYQGMGFQKTGHY-FVSIAKRLIGLSIFHFTYSLPSVWEPRM------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RDW3-1", "uniprot_id": "M0RDW3_RAT", "id": "M0RDW3-1", "name": "", "aln": "MAPYHIRQFQDRDHRRVLDLFSRGMEEHVPAAFYHVLTLPHSLLLFPGVPVTIILVSGSWLLATVYSFLFLLCLRLLIWFSWRNYVAMCLKSDLADITKSYLNAHGS-FWVAESGGQVVGIVGSLPVKEPPSGRRQLQLFRLSVSSQHRGQGIAKALVRTVLQFARDQGYTDVVLQTSSVQYSAMSLYQGMGFQKTGQH-FMSITTRLIGLPIFHFTYSLPSVWEPRM------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHQ9-1", "uniprot_id": "NT8F2_MOUSE", "id": "Q8CHQ9-1", "name": "N-acetyltransferase family 8 member 2", "aln": "MAAYHIRQYQEKDHKRVLELFSSGMKELIPAAIRQMLTLPHSLLLLPGVPVTIVLMSASWLLATLYSFLFLLCLWLIFWISCRNYVAKSLQADLADITKSYLNAHGS-FWVAESGDQVVGMVGAQPVKDPPLGKKQMQLFRLSVSSQHRGQGIAKALVRTVLQFARDQGYSDVVLETGSVQHSAQALYQAMGFQKTGQY-FVSISKKLMGLSILQFSYSLPFASGPGYSGKYLKKGPIPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHE5-1", "uniprot_id": "NAT8_HUMAN", "id": "Q9UHE5-1", "name": "N-acetyltransferase 8", "aln": "MAPCHIRKYQESDRQWVVGLLSRGMAEHAPATFRQLLKLPRTLILLLGGPLALLLVSGSWLLALVFSISLFPALWFLAKKPWTEYVDMTLCTDMSDITKSYLSERGSCFWVAESEEKVVGMVGALPVDDPTLREKRLQLFHLFVDSEHRRQGIAKALVRTVLQFARDQGYSEVILDTGTIQLSAMALYQSMGFKKTGQS-FFCVWARLVALHTVHFIYHLPSSKVGSL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSN6-1", "uniprot_id": "A0A8M1PSN6_DANRE", "id": "A0A8M1PSN6-1", "name": "", "aln": "MDEVQIRQYREEDLEEVKEVFTIGMSEHIPSSCMHVLKQPLAQMFLGCVFCALLTSSMSILLPVLAVTLLLAAGRQSVCYMFNKYIQTSLEQDLSHIQQTYMDPPNACVWVAESQGRVVGTVGCFPSEN---DKNFLELKRMSVKKAHRGKGIAKALCRTVADFARERGYLGVILHTSVVQTDAQKLYEHMGYHKVREFSAPEFIAKLTNFTLMEYQLIVKRHN----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**:::: * . * ::: ** * *:: ::*. * : ::: ::: * * **. : :: . :*: * *::.* ::*:. .: .***** :*** *.. * .: .. ::* :: *.. ** :****** * * :***::** *:* *. :* .* **: **::*. . . :* : ..: : ", "identical_positions": 58, "similar_positions": 71, "identity": "24.17%" }, { "cls_id": "homologset.agr.MGI:2136449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXS4-1", "uniprot_id": "NT8F3_RAT", "id": "Q9QXS4-1", "name": "N-acetyltransferase family 8 member 3", "aln": "MAPYHIRKYQDSDHRSVVNLFCRGTEEHISASFRYMLLLPGTLLILLGVPLTLFLASGSWLLVLLSTLTLLVSLWLLAKYPWEKYTAMCLHSDMADIPRTYLSSHYSCFWVAESRGQMVGIIAVLPVKDPLLQRKQLQLRHLSVSLEHRREGIGRAMVRTALQFAEMQGFSEVVLVTSMLQYAALALYQSMGFQKTGEF-FYTFVSRLRNSPMICLKYCLTSA-LNDLKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIY8-1", "uniprot_id": "NT8F3_MOUSE", "id": "Q9JIY8-1", "name": "N-acetyltransferase family 8 member 3", "aln": "MAPYHIRKYQDSDHRSVVDLFRRGMEEHIPATFRHMLLLPRTLLLLLGVPLTLFLASGSWLLVLLSILTLFLSLWFLAKYTWEKHVMNCLHTDMADITRTYLSSHSSCFWVAESRGQTVGMVAARPVKDPLLQKKQLQLLHLSVSLQHRREGLGKAMVRTVLQFAQMQGFSEVVLSTSMLQYAALALYQGMGFQKTGET-FYTYLSRLRKSPMINLKYSLTSR-EGDL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHE5-1", "uniprot_id": "NAT8_HUMAN", "id": "Q9UHE5-1", "name": "N-acetyltransferase 8", "aln": "MAPCHIRKYQESDRQWVVGLLSRGMAEHAPATFRQLLKLPRTLILLLGGPLALLLVSGSWLLALVFSISLFPALWFLAKKPWTEYVDMTLCTDMSDITKSYLSERGSCFWVAESEEKVVGMVGALPVDDPTLREKRLQLFHLFVDSEHRRQGIAKALVRTVLQFARDQGYSEVILDTGTIQLSAMALYQSMGFKKTGQS-FFCVWARLVALHTVHFIYHLPSSKVGSL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UHF3-1", "uniprot_id": "NAT8B_HUMAN", "id": "Q9UHF3-1", "name": "N-acetyltransferase 8B", "aln": "MAPYHIRKYQESDRKSVVGLLSGGMAEHAPATFRRLLKLPRTLILLLGGALALLLVSGSWILALVFSLSLLPALWFLAKKPWTRYVDIALRTDMSDITKSYLSECGSCFWVAESEEKVVGTVGALPVDDPTLREKRLQLFHLSVDNEHRGQGIAKALVRTVLQFARDQGYSEVVLDTSNIQLSAMGLYQSLGFKKTGQS-FFHVWARLVDLHTVHFIYHLPSAQAGRL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSN6-1", "uniprot_id": "A0A8M1PSN6_DANRE", "id": "A0A8M1PSN6-1", "name": "", "aln": "MDEVQIRQYREEDLEEVKEVFTIGMSEHIPSSCMHVLKQPLAQMFLGCVFCALLTSSMSILLPVLAVTLLLAAGRQSVCYMFNKYIQTSLEQDLSHIQQTYMDPPNACVWVAESQGRVVGTVGCFPSEN---DKNFLELKRMSVKKAHRGKGIAKALCRTVADFARERGYLGVILHTSVVQTDAQKLYEHMGYHKVREFSAPEFIAKLTNFTLMEYQLIVKRHN------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**:*::.* . * :: * ** .:: :* * : ::* :*: * * :* :: *: : . : .: * *::.* ::*:. :*.*****. : ** :. * .: .: *:* :: *. ** :*:.:*: **. :**. :*: *:* *. :* * **: :*::*. : ::* : : ", "identical_positions": 52, "similar_positions": 70, "identity": "22.61%" }, { "cls_id": "homologset.agr.MGI:2136459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TT49-1", "uniprot_id": "MRCKB_RAT", "id": "Q7TT49-1", "name": "Serine/threonine-protein kinase MRCK beta", "aln": "-------------MSAKVRLKKLEQLLLD-----------GPWRNESSLSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTD---VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNIEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSMIQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSTRALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTQRLKGLEKQYRLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMAELRSQKQKVSRQLRDKEEEMEVAMQKIDSMRQDIRKSEKSRKELEARLEDAVAEASKERKLREHSESFSKQMERELETLKVKQG-GRGPGATLEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHESESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGAMKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVHEELRKVKDTSLAFESKLKESEAKNRELLEEMQSLKKRMEEK-----FRADTGLKLPDFQDPIFEYFNTAPLAHDLTFR-----------------TSSASDQETQASKLDLSPS---------VSVATSTEQQEDAARSQQRPSTVPLPNTQALAMAGPK-----PKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFAVSSVLASDVIHATRRDIPCIFRVTASLLGSPSKTSSLLILTENENEKRKWVGILEGLQAILHKNRLRSQVVHVAQEAYDSSLPLIKTVLAAAIVDGDRIAVGLEEGLYVIELTRDVIVRAADCKKVYQIELAPKEKLILLLCGRNHHVHLYPWTSFDGAEASNFDIKLPETKGCQLIATGTLR--KSSSTCLFVAVKR-----LVLCYEIQRTKPFHRKFNEIVAPGHVQWMAMFKDR-LCVGYPSGFSLLSIQGDGQPLDLVNPADPSLAFLSQQSFDALCAVELKS------EEYLLCFSHMGLYVDPQGRRSRTQELMWPAAPVACSCSSSHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSDGSLNLLGCEPPRLIYFKNKFS-GTVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAPTA-------------------------------QEE-------------KQGPAPTGLPR---------------------QLPSRNKPYVSWPSSGGSEPGVPVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLDQPACDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT50-1", "uniprot_id": "MRCKB_MOUSE", "id": "Q7TT50-1", "name": "Serine/threonine-protein kinase MRCK beta", "aln": "-------------MSAKVRLKKLEQLLLD-----------GPWRNDSALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTD---VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDMLRNIEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSMTQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSTRALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTHRLKGLEKQYRLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMSELRSLKQKVSRQLRDKEEEMEVAMQKIDSMRQDLRKSEKSRKELEARLEDAAAEASKERKLREHSESFCKQMERELEALKVKQG-GRGPGAASEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGTVKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDSSLAFESKLKESEAKNRELLEEMQSLRKRMEEK-----FRADTGLKLPDFQDSIFEYFNTAPLAHDLTFR-----------------TSSASDQETQASKMDLSPS---------VSVATSTEQQEDMARPQQRPSPVPLPSTQALAMAGPK-----PKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVVASQVLDLRDEEFAVSSVLASDVIHATRRDIPCIFRVTASLLGSPSKTSSLLILTENENEKRKWVGILEGLQAILHKNRLKSQVVHVAQEAYDSSLPLIKAVLAAAIVDGDRIAVGLEEGLYVIELTRDVIVRAADCKKVYQIELAPKEKIAILLCGRNHHVHLYPWSSFDGAEASNFDIKLPETKGCQLIATGTLR--KSSSTCLFVAVKR-----LILCYEIQRTKPFHRKFSELVAPGHVQWMAVFKDR-LCVGYPSGFSLLSIQGDGPPLDLVNPTDPSLAFLSQQSFDALCAVELKS------EEYLLCFSHMGLYVDPQGRRSRMQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSDGSLNLLGCEPPRLIYFKNKFS-GTILNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAPTV-------------------------------QEE-------------KQGPTPAGLPR---------------------QPPSRSKPYVSWPSSGGSEPGVPVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPMEGLDQPSCDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5S2-1", "uniprot_id": "MRCKB_HUMAN", "id": "Q9Y5S2-1", "name": "Serine/threonine-protein kinase MRCK beta", "aln": "-------------MSAKVRLKKLEQLLLD-----------GPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTD---VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQG-GRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELEALRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEK-----FRADTGLKLPDFQDSIFEYFNTAPLAHDLTFR-----------------TSSASEQETQAPKPEASPS---------MSVAAS-EQQEDMARPPQRPSAVPLPTTQALALAGPK-----PKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVTASLLGAPSKTSSLLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPLEAYDSSLPLIKAILTAAIVDADRIAVGLEEGLYVIEVTRDVIVRAADCKKVHQIELAPREKIVILLCGRNHHVHLYPWSSLDGAEGS-FDIKLPETKGCQLMATATLK--RNSGTCLFVAVKR-----LILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDR-LCVGYPSGFCLLSIQGDGQPLNLVNPNDPSLAFLSQQSFDALCAVELES------EEYLLCFSHMGLYVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSEGTLNLLNCEPPRLIYFKSKFS-GAVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPS-------------------------------QEE-------------RPGPAPTNLAR---------------------QPPSRNKPYISWPSSGGSEPSVTVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPACDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2Q2-1", "uniprot_id": "A0A8M9P2Q2_DANRE", "id": "A0A8M9P2Q2-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------MSAKVRLKKLEQLLLD-----------GHQKNDKSLSVETLLDILICLYNECSNSPLKREKHVTDFLEWVKPFTTTVKEMRLHRDDFEMLKVIGRGAFGEVAVVKMKHTERVYAMKILNKWEMLKRAETACFREERNVLVNGDCQWITTLHYAFQDDNYLYLVMDYYVGGDLLTLLSKFEDRLPEDMAKFYVAEMVLAIHSIHQQRYVHRDIKPDNVLLDMNGHIRLADFGSCLKMMQDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHITD---VSEDAKDLIQRLICSRERRLGQHGIEEFRKHAFFSGIDWENIRNMEAPYIPDVSSPSDTSNFDVDDDVLKNPDIAPPVSHTGFTGQHLPFVGFTYTTESCFSDGGSMRGVALSDGGTG-EDLQ---DGGMQVEAFEKRIRCLEQEKLELNRKLQESTQAVQSLHGSGRGAGTLGRDKEIKKLNEEIDRLKKKLADSDRLEHQLEEAVTLRQDFESSSTKLKALDKQVKALKLEKEDIHKQLVESLDRLKSQTKELKDAHQQRKLAMQEFSEVNERMAELRSQKQRLSRQLRDKEEEMEVVMQKIDAMRQDIRKTEKARKELESQLEDARAEASKERKLREHSEVYSKQLESELETLKVKQGTGRASGLGAETQQELTKLKSELDKKGLYYEEELVRREASHTTEMKNLRKELQDSEGQQLSLHKELLALKEKLEKAKRERQIEMEEAINALKEQYERERNLMSEDNRKLTAETDRLCSFVDKLTAQNRQLEDELQELASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELESLRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVHDELRKVKAANISFESKLKDTEAKNRELEEQLENMKKEMEESR----SRSDKGLKLPDFQDSIFDYFNTSPLAHELTFRDSVSSSSASSLLAFWDETSSVGDVDVAPQKTDIPPS---------SPSAAT--EQDEAVKPQATTPATPSPMYQP-TLTAPK-----PKAHQLSIKTFSSPTQCTHCTSLMVGQMRQGYACEVCSFICHVSCKDNAPQLCPIPPEQTKRPLGIDVQRGIGTAYKGFVRIPKPTGVKKGWQRAYAVVCDCKLFLYEVPEGKSTQPVVMASQVLDLRDEEFSVSSVLASDVIHANHKDVPCIFRVTSSALKSSIRPVPLLILAESEAEKRKWVGILEGLQSILAKNRLKNRVVHVLHEAYDSSLPAIKTTLSAAIVDRERIVLGTEDGLFVVEITRDVIVRAADCKKVCQIELIPKEKMVALLSGRNRHVHLYPWAALEGAEGG-FDTKLTDTRGCQAMTIGNLR--PGGPACLFAGVKR-----QVFCYEITRAKPHHRKLWEVQAPGVVQWLGIIRER-ICVGYPSGFALLAMQGESSPVSLVSPGDPSLAFLAQQPLDALHAMEVGS------NELLLCFSQLGVYVDATGRRSRTQELMWPSTPLACSSNSNCLTVYSDYGVDVFDVHTMEWVQTISLRKIRPLNVEGSLNLLSIEQPHLIYFSNNSSDGCDLAIPETSDNSKKLMVRTRSKRKFLFKVPEEERLQQRREMLRDPEMRSKLISHPTNFNHVAHMGPGDGMQVLMDLPLPSETPSPSSSRHHALISPPTNFEHVYHMSPVSAGLYLQKEPSSQQSLLQFSSSSSSPSTSSLGRSVMPSSQDDLSKDKPRPLSSISRQQRSKTHITRTASGGGDFGGAGSSRSISDQDQDYEREPDSDSTKHSTPSNSSNPSSPPSPNSPHRSQLTLDSLDQSLDG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1B0-1", "uniprot_id": "GEK_DROME", "id": "Q9W1B0-1", "name": "Serine/threonine-protein kinase Genghis Khan", "aln": "MEYESSEISDITTGSCKKRLTFLKCILSDTTSDQKWAAEFGEDTEGHQFSLDYLLDTFIVLYDECSNSSLRREKGVSDFLKLSKPFVHIVRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFDVDDNDVRLTDSIPPSANPAFSGFHLPFIGFTFS---------------------------------------------------------LTSSSTLDSKKNQSSGFG-----------DDTLDTISS---------PQLAILPSNNSETPVDSVQLKALNDQLAALKQEKAELSKQHNEVFERLKTQDSELQDAISQRNIAMMEYSEVTEKLSELRNQKQKLSRQVRDKEEELDGAMQKNDSLRNELRKSDKTRRELELHIEDAVIEAAKEKKLREHAEDCCRQLQMELR----KGSSSVETTMPLSISSEMS--SYEIERLELQFSEKLSHQQTRHNMELEALREQFSELENANLALTKELQQTQERLKYTQMESITDSAETLLELKKQHDLEKSSWFEEKQRLSSEVNLKSKSLKELQAED---DEIFKELRMKREAITLWERQMAEIIQWVSDEKDARGYLQALATKMTEELEYLKHVGTFNNNGVDNKNWRNRRSQKLDKMELLNLQSALQREIQAKNMISDELSQTRSDLISTQKEVRDYKKRYDSILHDFQKKETELRDLQKGGLEYSESFLNKSTHHGLSSAFFRDMSKNSEIIDS-----------------AESFGNESGDNFTPNFFQSGNSGMLFNYEPKYAGKNNKDHSSMKEASVSDLSREESDQLVKESQKKVPGNTAIHQFLVRTFSSPTKCNHCTSLMVGLTRQGVVCEICGFACHTICCQKVPTTCPVPMDQTKRPLGIDPTRGIGTAYEGYVKVPKSGVIKRGWIRQFVVVCDFKLFLYDISPDRCALPSVSVSQVLDMRDPEFSVGSVRESDVIHAAKKDVPCIFKIKTALIDGG-LSLNTLMLADNESEKSKWVIALGELHRILKRNSLPNTAIFKVNEILDNTLSLIRNALCSVIIYPNQILLGTEDGLFYINLDQYEIARIGESKKILQLWYIEEEQILVILCGKQRNLRLLPIRALEASDVE--WIKVVESKNCISACTGIIRRFPNIVYSFIIALKRPNNHTQIVVYEINRTRTRHQKTCEFTIGYMAQHLQILSDMRLVVAHQSGFTAYFLRGEATAMSLVHPENQLCAFLNYSGVDAVRVIEILCPSGGNFGEYLLVFQTLAIYVDLQGRKSRDREIMYPAFPTYITFCDGHLLVFSDTHLDIFNTQTAEWVQSIGLKQSLPLNNLGNVVLSSVNDTPLIVYLSNIH---TKGLLQYRDGNRKGLP--SIKRRFSIREINKTIKSDR---------RSKMISAPTNFNHISHMGPGDGIQNQRLLDLPTTLET--------------------------------------------------------------------------------------------ADQACSPIIHSLSCIPQSRKSNFLEQVDANSDDYG---NDNIISRTPSPMASS----FMDGLSNND---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* **. *: :* * * : :*:: *** :: ** ***:*.*:*:* *::**: ***. *:.::* *:**:::*:*********.**:* **::************************:*** ** **** *******: ******** *************:******:**: **:***.**** :************** .**:*********:: .******.**************:***** *:**.************************************:: *::**: * *** ::**: :*** *.****:**::* .*.:* *::*:***: ***:*:****:*********: :: : ** ::..*:* ****:***:: *:.:::* :.. . . :: :: :.. ** : ..: .: :*:.*:.* : ** :: ** * :***:* .**:** .**: *: *:**:.*:::*** **::***:******:: . ** *::*:::*:::* *:*** :::** **:**:*****:* .:*:: **. * . . . . ..*:: *::: * :.*:* :::: * *:: ::::. : *. :*:* **: :::*: :: * : *:: :*.::: *: :::::*::* : .. :.:* *:: :: :::* *:*::: ** *:*********************:******* *: ::... :* *: ******* *:*****: **:**::: :** :.: :: :.:::: : : .: .::: ...:.: ::. *: . .:. :*. . :: :.* .: . . : * . : :::. . . : . . * . **: :::*.***:*.******** *** .**:*.* **. * : .* **:* :*:*****:* *******:*.*::**. :*:** * :.**** *****::. .:.: * * .*****:** **:*.** ****** ::*:****::.:: : . . *:*::.* ** *** * *: ** :* * . .:. * *.:*. *: * :.*: ::* :* *:**: ::: : *.* .:.**: *: .*:: :*.*::::::* * :::.:: *: :::.* . :: . .:: .:** :. *** *::. *:* *. .* : :: : : *.: *** ::*:. .:.** * : *** . .**: .:*: . * ** *. :.:*** **::* :*:*:*: * : : *:*: :*:*:.:* ****:*.*:: *** *.: * . : . ** : .: : : *..:* : **:* :: :: .:* ***:** ******::*******:* * *.: :. . . .. ..:: .: *::* .:. *.. * .*** :. ::.*.: ", "identical_positions": 631, "similar_positions": 514, "identity": "33.94%" }, { "cls_id": "homologset.agr.MGI:2136460", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH95-1", "uniprot_id": "ECHM_MOUSE", "id": "Q8BH95-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MAAL-RALLPRACSSLLSSVRCPELRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEQDPAVGAIVLTGGDKAFAAGADIKEMQNRTFQDCYSSKFLSHWDHITRVKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVEKLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGNKLEKRLFYSTFATDDRREGMTAFVEKRKANFKDH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14604-1", "uniprot_id": "ECHM_RAT", "id": "P14604-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MAAL-RALLPRACNSLLSPVRCPEFRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANFKDH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30084-1", "uniprot_id": "ECHM_HUMAN", "id": "P30084-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MAAL-RVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZZ04-1", "uniprot_id": "Q7ZZ04_DANRE", "id": "Q7ZZ04-1", "name": "Enoyl-CoA hydratase, mitochondrial", "aln": "MALLCRSTGLLLKHSKLLPSALAATRQSSSGVQYEYILVDKKGEKKNVGFIQLNRPKALNALCDGLMLEVGKALDAFEMDSEVGAIVVTGSEKAFAAGADIKEMQNRTFQECYGGNFLAHWNRVSTVKKPVIAAVNGFALGGGCEFAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQEAKQSGLVSKIFPVDQLVPEAIKCGEKIAGNSKLVSAMAKESVNAAFELTLAEGSRFEKRLFHATFATEDRKEGMSAFVEKRKAAFQDK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * * . . . * :**.:::**:.:*:*::..**:*************:**: *:.:**.:** *. *****:**.:************** :**:**..:** **:::: :**********:*:*****:***************.*****:**********************************:***:****** **: ** ***:*.****.***:: ************:**:**.::**:**::****:**:***:******** *:*:", "identical_positions": 196, "similar_positions": 64, "identity": "67.35%" }, { "cls_id": "homologset.agr.MGI:2136650", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925N7-1", "uniprot_id": "CL2D5_RAT", "id": "Q925N7-1", "name": "C-type lectin domain family 2 member D5", "aln": "---MPSSAHLQDPPPLLSRTLTQNEGQTS--LRQSSSCGPSAASASESL----SGSTESRIPHS----KMLQGKLPRNIPLEYPAGLYCCYVVIIVLSVAVVALSVALSVKKT--AQISTINTYAACPRNWIGVGNKCFYFNEIPSNWTLSQTLCKEQGAELARFDTEEELNFLRRYKGSSGYWFGLHRESSAHPWKWTDNTEYNNSVSIGGDEKHGFLSDNGFSSGRGYIVRKSICRKPNSYTSQCL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4KWA5-1", "uniprot_id": "CL2D2_RAT", "id": "A4KWA5-1", "name": "C-type lectin domain family 2 member D2", "aln": "---MPSSAHLQDAPPLLSRTLTQDEEQTS--LRQSSSCGLSAASASESL----SGSTKSRIPHS----KMLQGNLPRIISPESPAKLPCCYGVIMVLSVAVVALSVALSVKKT--PQILTVKTYAACPRNWIGVGNKCYYFNETPSNWTFSQTLCKAQEAELARFDTEEELNFLKRHKGSSGYWIGLHRESSSQPWKWTDNTAYNNLVPIGGDEKHGFLSDNGFSSGRGYIVRKSICSKPNSYTSQCQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LRV1-1", "uniprot_id": "A0ABK0LRV1_RAT", "id": "A0ABK0LRV1-1", "name": "", "aln": "MRNMQQSLEMRSSRDEDSMRLMKTEVTTTDFLEEGETVEMRSSRDEDSMRLMKTEDTTTDFLKEGETGEMLHGNCLRIFSPESPAKLYCCYAVILVLTVAVVALSVALSVKKT--PQISNINAYAACPRNWIGVGNKCFYFSEYASNWTFSQDFCKAQESQLARFDNQEELNFVKRYKGSSNYWIGLHRESSEHPWKWTDNTEYNNLVSIRGDELLGFLSDSGISSSRNYIKRNWICSKPNNYTSQCK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVF9-1", "uniprot_id": "CLC2I_MOUSE", "id": "Q9WVF9-1", "name": "C-type lectin domain family 2 member I", "aln": "---MPDCLETG------EKLFVHN---------MNAQCVQKPEEGNGPLG---TGG------------KIVQGKCFRIISTVSPVKLYCCYGVIMVLTVAVIALSVALSTKKT--EQIIINKTYAACSKNWTGVGNKCFYFSGYPRNWTFAQAFCMAQEAQLARFDNEEELIFLKRFKGDFDCWIGLHRESSEHPWKWTNNTEYNNMNPILGVGRYAYLSSDRISSSRSYINRMWICSKLNNYNLHCQTPPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHP7-1", "uniprot_id": "CLC2D_HUMAN", "id": "Q9UHP7-1", "name": "C-type lectin domain family 2 member D", "aln": "---MHDSNNVEK---------------------DITPSELPANPG------------------------CLHSKEHSIKAT----LIWRLFFLIMFLTIIVCGMVAALSAIRANCHQEPSVCLQAACPESWIGFQRKCFYFSDDTKNWTSSQRFCDSQDADLAQVESFQELNFLLRYKGPSDHWIGLSREQG-QPWKWINGTEWTRQFPILGAGECAYLNDKGASSARHYTERKWICSKSDIHV--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. . . ::.: . : : :*:.*:: * .: .***. :: * ***...* *. .**:**. . *** :* :* * ::**:.:. :** *: *.** . *:** **.. :**** :.* :.. .* * .:*... **.* * * ** * : : ", "identical_positions": 52, "similar_positions": 60, "identity": "20.63%" }, { "cls_id": "homologset.agr.MGI:2136689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTF0-1", "uniprot_id": "E9PTF0_RAT", "id": "E9PTF0-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAELRLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVTQALELSRKPHVVIATPGRLADHLRSS--NTFN-MKKIRFLVLDEADRLLEQGCTDFTADLETILSAVPAR--RQTLLFSATLTDTLKELQGLATN--QP----FFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALARFKSSTYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLLHAIEEEIKQQLAEL--AVEEAQVLQILTQVNVVRRECEIKLEASHFDEKKEINKRKQMILEGKDPD------------------------LEAKRKAELAKIKQQNRRFKEKVEQTLRQQKAGSTGRRSRPPRPRP-QEPARAEAQN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4FZF3-1", "uniprot_id": "DDX49_MOUSE", "id": "Q4FZF3-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAEIGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS--NTFN-MKKIQFLVMDEADRLLEQGCTDFTTDLETILAAVPAR--RQTLLFSATLTDTLKELQGLATN--EP----FFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLLHAIEEQIKQQLAEL--VVEEAEVLQILTQVNVVRRECEIKLEASHFDEKKEINKRKQMILEGKDPD------------------------LEAKRKAELAKIKQQNRRFKEKVGQTLRRQKAGSTVRRSRPPRSRP-QEPAQAEAQD------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6V7-1", "uniprot_id": "DDX49_HUMAN", "id": "Q9Y6V7-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS--NTFS-IKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPAR--RQTLLFSATLTDTLRELQGLATN--QP----FFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLVHAIEEQIKKKLEEF--SVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDPD------------------------LEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRTPSGSHSGPVPSQGLV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38719-1", "uniprot_id": "DBP8_YEAST", "id": "P38719-1", "name": "ATP-dependent RNA helicase DBP8", "aln": "-----MADFKSLGLSKWLTESLRAMKITQPTAIQKACIPKILEGRDCIGGAKTGSGKTIAFAGPMLTKWSEDPSGMFGVVLTPTRELAMQIAEQFTALGSSMNIRVSVIVGGESIVQQALDLQRKPHFIIATPGRLAHHIMSSGDDTVGGLMRAKYLVLDEADILLTS---TFADHLATCISALPPKDKRQTLLFTATITDQVKSLQNAPVQKGKPPLFAYQVESVDNVAIPSTLKIEYILVPEHVKEAYLYQLLT--CEEYENKTAIIFVNRTMTAEILRRTLKQLEVRVASLHSQMPQQERTNSLHRFRANAARILIATDVASRGLDIPTVELVVNYDIPSDPDVFIHRSGRTARAGRIGDAISFVTQ-RDVSRIQAIEDRINKKMTETNKVHDTAVIRKALTKVTKAKRESLMAMQKENFGERKRQQKKK---------------------------------------------------------------QNDGKSLRS-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07886-1", "uniprot_id": "DDX49_DROME", "id": "Q07886-1", "name": "Probable ATP-dependent RNA helicase Dbp45A", "aln": "MQRKEANPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEPVSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLADHLTGC--DTFS-FDNLKYLVVDEADRMLNG---DFDESLSIIERCLPKT--RQNLFFSATMKDFIKESSIFPIAS-----DCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENANVMIFTNTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEH--PIDQRMVERIFMQVNVTRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDKLREIRRKRKLQHAEPAASEEGKALLQDERFKSVDSARFEKKGKGRSRATQEDTPTKPLKRLNKEKPVAQKGRADVKKDKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * **.:. : :. .*.:* *** ** *:**:* ******** **. *:* : **:* . * :*****:*** **:*** . *..:.:: .:: ** . : :: .* ::**.::* *****.*: .. :*.. : . ::**:**** :* * * .:* **.*:*:**:.* ::. . . : . * . *. .*:* .: :: * . : :: *: . :**.* .::* *:::.. ..**. * *:** :* :*::. * *******:******:*::*:*: * *. :*** ******** * :*::. *: : ***:.*: :: * : : : : :*. .:**. : :: .*.*: . ::* : * : ", "identical_positions": 139, "similar_positions": 139, "identity": "25.93%" }, { "cls_id": "homologset.agr.MGI:2136690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27545-1", "uniprot_id": "CERS1_MOUSE", "id": "P27545-1", "name": "Ceramide synthase 1", "aln": "MAAAAATPR------------------LEAPEPMPSYAQMLQR--SWASALAAAQGCGDCG----------WGLARRGLAEHAHLAAPELLLAVLCALG-------------------------------------------WTALRWAATTHIFRPLAKRCRLQPRD-AARLPESAWKLLFYLACWSYCAYLLLGTSYPFFHDPPSVFYDWRSGMAVPWDIAVAYLLQGSFYC-HSIYATVYMDSWRKDSVVMLVHHVVTLLLIASSYAFRYHNVGLLVFFLHDVSDVQLEFTKLNIYFKARGGAYHRLHGLVANLGCLS--FCFCWFWFRLYWFPLKVLYATCHCSLQSVPDIPYYFFFNILLLLLMVMNIYWFLYIVAFAAKVLT-GQMRELEDLREYDTLEAQTAKPCKAEKPLRNGLVKDKLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27544-1", "uniprot_id": "CERS1_HUMAN", "id": "P27544-1", "name": "Ceramide synthase 1", "aln": "MAAAGPAAG------------------PTGPEPMPSYAQLVQR--GWGSALAAARGCTDCG----------WGLARRGLAEHAHLAPPELLLLALGALG-------------------------------------------WTALRSAATARLFRPLAKRCCLQPRD-AAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYG-HSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLS--FGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLT-GQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28496-1", "uniprot_id": "LAC1_YEAST", "id": "P28496-1", "name": "Ceramide synthase LAC1", "aln": "MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFN--TKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDS-GLAFFSFAIFVVAWIYLRHYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVF-VLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEESDESSTTPTDSTPTKKDI------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: .:. :.:** . :.: . :* : :. * *. .** :*. :*: . * :* ** ::**:* * : .:. :: *. : ::: . .: * : :. **: ...:* ..:: * : . ** *.:*: :: .: ::. *** : .**:***:** ***.*:: ::*: : : *:**. *.*:* *:.: * ::. : :.. * : : :* * * : *. ..: : *. :.* *: * ::*:**:: *. . ::* * ::: .. * * . :: .. . ..* ::.: ", "identical_positions": 69, "similar_positions": 131, "identity": "16.12%" }, { "cls_id": "homologset.agr.MGI:2136691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZW6-1", "uniprot_id": "HILS1_RAT", "id": "D3ZZW6-1", "name": "Histone H1.9", "aln": "-----------------------------------MSLVSPSPDSNAVMAGDQ---------------DAS----------------TSQVPS----QSESKIGPNVATQTLRKPTMSKVILRTVADKGVHSRVSLAALKKAVSITGYNMAQNTWRFKRVLQNLVKKGMLKQVTG-KGASGSFRLGKKQAFKSKCKAKRRQRRQK------PGQRRTGSRRSLLGSKKSNNRLFKGVRRVAKGRRH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYL0-1", "uniprot_id": "HILS1_MOUSE", "id": "Q9QYL0-1", "name": "Histone H1.9", "aln": "--------------------------------------------MAQMVAGDQ---------------DAG----------------TLWVPS----QSESQTESDISTQSLRKPTMSYVILKTLADKRVHNCVSLATLKKAVSITGYNMTHNTWRFKRVLQNLLDKGMIMHVTCCKGASGSLCLCKERALKSNHRAKRCQDRQKSQKPQKPGQRESEPCQLLLSSKKKNDQLFKGVRRVAKGNRHCHY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60008-1", "uniprot_id": "HILS1_HUMAN", "id": "P60008-1", "name": "Putative histone H1.9", "aln": "MLHASTIWHLRSTPPRRKQWGHCDPHRILVASEVTTEITSPTPAPRAQVCGGQPWVTVLDPLSGHTGREAERHFATVSISAVELKYCHGWRPAGQRVPSKTATGQRTCAKPCQKPSTSKVILRAVADKGTCKYVSLATLKKAVSTTGYDMARNAYHFKRVLKGLVDK----------GSAGSFTLGKKQASKSKLKVKR-QRQQR----WRSGQRPFGQHRSLLGSKQGHKRLIKGVRRVAK--CHCN-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*.* :* *: *:: .::. :**: * ***:::*** . . ****:****** ***:*::*:::*****:.*:.* *::**: * *::* **: :.** * :*: .*** : **.**: :.:*:******** * ", "identical_positions": 65, "similar_positions": 47, "identity": "26.1%" }, { "cls_id": "homologset.agr.MGI:2136733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5IXF8-1", "uniprot_id": "GLP2R_MOUSE", "id": "Q5IXF8-1", "name": "Glucagon-like peptide 2 receptor", "aln": "-----------------------------------------MRRLWGPGTPFLALLLLVSIKQVTTGSLLEETVQKWAQYKETCLKDLLEKPSGVFCNGTFDKYVCWPHSFPGNVSVPCPSYLPWWNKESPGRAYRHCLAQGTWQKQENSTDTWQDESECSENHSFKQNVDHYHHTLLSTLQLMYTVGYSLSLISLFLALTLFLFLRKLHCTRNYIHMNLFASFILRALVVLVKDMVFYNSYSRRPDSESGWMSYLSEISASCRSVQVLLHYFVGTNHLWLLVEGLYLHALLEPTVLPERRLWPKYLVVGWAFPMLFVIPWIFVRASLENTGCWAVNENKKIWWIIRGPILLCVTVNFFIFLKILKLLISKFRAHQMCFRDYKYRLAKSTLLLILLMGVHEFLFTFFTDDQVQGFSRLIRLFIQLTLSSFHGFLVALQYGFASREVKAELRKTWGRFLLARHWGCRACVLGKNFRFLGKCSKKLSEGDGAETLQKLQSSGVSS---HLTAGNLRDHGAQPHRGRGAWPRASSLSESSEGDFTLANTMEEILEESEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z0W0-1", "uniprot_id": "GLP2R_RAT", "id": "Q9Z0W0-1", "name": "Glucagon-like peptide 2 receptor", "aln": "MRPQPSPAVPSRCREAPVPRVRAQPVGIPEAQGPVPLHSQQMRLLWGPGRPFLALLLLVSIKQVT-GSLLKETTQKWANYKEKCLEDLHNRLSGIFCNGTFDRYVCWPHSYPGNVSVPCPSYLPWWNAESPGRAYRHCLAQGTWQTRENTTDIWQDESECSENHSFRQNVDHY--ALLYTLQLMYTVGYSVSLISLFLALTLFLFLRKLHCTRNYIHMNLFASFILKVLAVLVKDMVSHNSYSKRPDDESGWMSYLSETSVSCRSVQVLLHYFVGTNHLWLLVEGLYLHTLLEPTVFPERRLWPKYLVVGWAFPMLFVIPWGFARAHLENTRCWATNGNLKIWWIIRGPMLLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLLLIPLLGVHEVLFTFFPDDQVQGFSKRIRLFIQLTLSSVHGFLVALQYGFANGEVKAELRKSWGRFLLARHWGCRTCVLGKNFRFLGKCSKKLSEGDGSETLQKLRFSTCSS---HLASETLGDVGVQPHRGRGAWPRGSSLSESSEGDFTLANTMEEILEESEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95838-1", "uniprot_id": "GLP2R_HUMAN", "id": "O95838-1", "name": "Glucagon-like peptide 2 receptor", "aln": "MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVT-GSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRY--ALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.** ***:*:********* ****:**.:***:**: **.** :. **:*******:******* ***************. **.**************. **:** ***:*********:****:* :** ***********.***********:***********************:.*.*****:* :****:***.*.******** *.**************:*:***********:******:*******:**::*****:***:** *.** **** **:.* * *********::********************::******************:** *:****.**:*:.****:**:: ***********.************. ******** * ******* ***:*****:*******.********:*.*:**: * *. **: * : *.**::.:. ***.*****.****.*:*************", "identical_positions": 396, "similar_positions": 79, "identity": "71.22%" }, { "cls_id": "homologset.agr.MGI:2136740", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XZ4-1", "uniprot_id": "PCDB6_MOUSE", "id": "Q91XZ4-1", "name": "Protocadherin beta-6", "aln": "-------METTLAKTPEKRQVVFLAILLL--LWEAGSEAIRYSIPEETESGYLVAHLAKDLGFRVGELATRRARIHHRGNKELLQLDVETGNLLLKEKPDREALCG--ATEPCVLHFQIILENPVQFFQTELQLTDINDHSPEFPDTEMLLKIQESTQPAT-VFLLKAAQDSD-IGSNAVQNYTVSPNLHFHVVTLSRSDGRKYPELVLDRALDREEQPELTLILTALDGGAPPKSGTTTVRIEVVDINDNAPEFVQSLYSVEVPENS---PLDALVVTVSARDLDAGIHGNVAYSLFQGGGGPQPFVIDEITGEIRLKGALDFEATS-YYTMEIVATDSGGLSGKCTVAIQVLDVNDNAPKLTISSLTSSIPENAPEAVVAVFSVSDPDSGDNGRMVCSIQNELPFLLKPTFENYYTLAAEGPLDREIREEYNITIIVSDLGTPRLTTQHTITVQVVDINDNAPAFTQTSYTMFVHE-------NNNPALHIGTISATDSDSGSNAHITYS--------LLPPHDLQLSLASLVSINADNGQLFALRAMDYEALQAFEFHVVARDGGSPALSSQALVRVVVLDDNDNAPFILYPMQNASAPCTELLPRAAEPGYLVTKVVAVDSDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDVPKHRLLLLVKDNGEPPRSASVTLHVLLVDGFSQPYLPLP-EVQHDSSQDEDMLTLYLVIALASVSSLFLLSVLLFVGVRLCRRVREASLGACSVPE-GHFSGHLVDVSGMGTLSQSYQYEVCLSGDSGTTDFKFLNHYSQ------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5E4-1", "uniprot_id": "PCDB5_HUMAN", "id": "Q9Y5E4-1", "name": "Protocadherin beta-5", "aln": "-------METALAKTPQKRQVMFLAILLL--LWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVMCG--ATEPCILHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPESTQPGT-VFPLKIAQDFD-IGSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENS---PLNSLVVVVSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATP-YYNVEIVATDGGGLSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRE-------NNSPALHIGSVSATDRDSGTNAQVTYS--------LLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLP-EAAPAQAQ-ADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPE-GPFPGHLVDVSGTGTLSQSYHYEVCLTGDSGAGEFKFLKPIIPNLLPQGAGEEIGKTAAFRNSFGLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LHM7-1", "uniprot_id": "A0A0B4LHM7_DROME", "id": "A0A0B4LHM7-1", "name": "", "aln": "MRINHQWIYYAILSLCWFNKATLGAILDSRCYLEGGGSAESFLATEDLAVGSIIGKLRING---DANAETGDINLSLREKNAPVEIHPGTKELALSVELDKEGVRGPSSIYVNVICIRRHSTDPSFVIPVNVRVTDVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQFLNPLEG---TLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPKFQRESYSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTIVQSQD-AKYFRIHPHNGAISLLTPIGYADVANGATLVVKATQIDNPDRYALTTVQLTRPGSHSDLSTLAFVQKRFVMRIREDTAVGNRILALPTNKPGKHLKYVIPDPVNSQFFSVGSLGELVLAKPLDYEKMTKHEFQVLATDGMTN---STAELTLEVIDVNDWEPRFRETHYEFMVPKSSLQSRADSFEGVLIGKVEAADGDRNDKLELSLRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVHLIAIATDTGVPPRSTSVPVSVTMEGLTLARSGWNSNMLGMFG---MIMGLFLMIIVALSCYIVRSKKQGKSASSGLGLGRNRVHSQAHSSVSSANLVTHEKLAGNGNGNGASVTSGGVSVLHMKHGGNITMANPMNNGLHHVASGASSSMALGSSAALLERERERERDRERQRESYAATVRIFLPGIVSRASANGQLFEEDEIEHDSLQTENNNRKVAATGVASGGVTTIS--TTPANAGSNLLSATDAMGSSENNLTVYF--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . .:. : *** *.*..* : .*: * :.:* : .: * .: : :: :::. * :* * : *:* : * : :: :: :* .: .::::**:**::*:: . *.: * * *.* :: *:* * *. :. :* : *. : . . . ***.:*** *: :::: * * * *:**: . * :*: : * :*: *:* :. *..::* :. * :.* * * * . : *::.*. .: * *. .. * * .:.: .. .: : **: .. . . .:::: ..:: *:: : . . * ... : :.. *: : : : :. . *. .** * :::: : .:* * : :*: * *:** * * :* * ::* : :. .: **.:.*:* * . : .:: : .. : : .* *:* .. :*:*: : . :: .. * . * . * .:: : : *: : : .* : .: . :. : .* . .*. * . ** *: :* . : : :.: .: : .: :. * * . * * : : : : : *..: * . ** .: : : . .*. * .* :. :* * ::: :. :. *: : :: ", "identical_positions": 122, "similar_positions": 265, "identity": "14.7%" }, { "cls_id": "homologset.agr.MGI:2136742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5M0-1", "uniprot_id": "A0ABK0M5M0_RAT", "id": "A0ABK0M5M0-1", "name": "", "aln": "METALAKTPEKRQVIFLAILLLLWESGSEAIRYSMPEETESGYLIANLAKDLGLQIGELSTRGARIHHNGNKELLQLDAKRGNLLLKEKPDREALCGATEPCVLHFQIILENPVQFFQTDLQLTDINDHSPEFPDTEMLLKIQESVQPGTVFPLKAAQDSDIGSNAVQNYTVNPNLHFHVLTHSHTDGRKYPELVLDRALDREEQPELTLILTALDGGAPPKSGTTTVRIEVVDINDNAPQFVQSLYAVEVPEDSPLNALVVTVSARDLDTGIHGNVAYSLFQGSGGLQPFVIDEISGEIRLKGALDFEATPYYNMEIVATDSGGLSGKCTVSIQVVDVNDNAPKLTISSLTRSIPENAPEAVVAVFSVSDPDSGDNGRVLCSIQNELPFLLKPTFKNFYTLVTESPLDRESRAEYNITISVSDLGTPRLTTQHTITVQVSDINDNAPTFTQTSYTLFVHENNSPALHIGTISATDADSGSNGFINYSLLPPHDQQLALVSLISINSDNGQLFALRALDYEAVQAFEFHVGATDGGSPALSSQALVRVVVLDDNDNAPFVLYPLQNASAPCTELLPRAAEPGYLVTKVVAVDADSGQNAWLSFQLLKATEPGLFNVWAHNGEVRTARLLSERDVPKHRLLLVVKDNGEPPRSASIMLQVLVVDGFSQPYLPLPEVALNPTKEEDMLTLYLVIALASVSSLFLLSVLLFVGVRLCRKARAASLGDCSIPEGHFPGHLVDVSSAGTLSQNYHYEVCLTEDSGTSDFKFMNPIIPTSLLQDS-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XZ2-1", "uniprot_id": "PCDB8_MOUSE", "id": "Q91XZ2-1", "name": "Protocadherin beta-8", "aln": "METALTKTPEKRQVIFLAILLLLWEASSEAISYSMPEETESGYLVANLAQDLGLRVGELTTRGARIHHNGNKELLQLDAERGNLLLKEKPDREALCGATEPCVLHFQIILENPVQFFQTDLQFTDINDHFPEFPDTEMLLKIQEIAQPGTVFPLKAAQDPDIGSNAVQNYTVSPNLHFHVVTLSRSDDRKYPELVLDRALDREEQPELTLILTALDGGAPPKSGTTTVRIEVVDINDNAPQFLQSLYAVEVPENSPLNALVVTVSARDLDAGIHGNVAYSLFQGGGGPQPFVIDEITGEIRLKGALDFEATSYYTMEIVATDSGGLSGKCTVAIQVLDVNDNAPKLTISSLTSSIPENAPEAVVAVFSVSDPDSGDNGRMVCSIQNGLPFLLKPTFKNFYTLVTERPLDRESNAEYNITITVSDLGTPRLTTQHTITVQVSDINDNAPAFTQTSYTLFVHENNSPALHIGTISATDSDSGSNGLIIYSLLPPHDQQLGLASLISINSDNGQLFALRALDYEALQAFEFHVGATDRGSPALSSEALVRVVVLDDNDNAPFVLYPLQNASAPCTELLPRAAEPGYLITKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDAPKHRLLLLVKDNGEPLRSASVMLQVLVVDGFSQPYLPLPEVALNPTQEEDMLTLYLVIALASVSSLFLLSVLLFVGVKLCKKAREASLADCSIPEGHFPSHLVDVSGAGTLSQSYHYEVCLTEDSGTSDFKFMNPIIPSSLLQDS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5E4-1", "uniprot_id": "PCDB5_HUMAN", "id": "Q9Y5E4-1", "name": "Protocadherin beta-5", "aln": "METALAKTPQKRQVMFLAILLLLWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVMCGATEPCILHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPESTQPGTVFPLKIAQDFDIGSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVVVSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIVATDGGGLSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAP-AQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYHYEVCLTGDSGAGEFKFLKPIIPNLLPQGAGEEIGKTAAFRNSFGLN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***:****:**********:.***: **:******** :****:**** :***:*****:*::********* : ***** ** ***.:*******:****::*************:****** ****:.****** * .********* *** *****:*****:.** **** * .: *.*********:******:***:* **********:*****:** *:* *****:*:**:* *:***:****:***.*******:* :*.***:****. ******* :.***** *******.**.:******.*********:*:*:*******:**:*:*: . ******:*****************::***** ********:********: .*****.*******:*:*:*****.*:*.*** ***:*****:**********:**********::**** ***:*. : ******:: :* *.**:***:***:*****:*****:*****:***** *******:*****:*** ***:*********.*******:*********:******* *********:***********.:*********:*******..****:::******* ***: *:**:*************.* . : * **:***:**********:******.*:**:::* *.:. **:*** **.******.:*****.******** ***:.:***::****. * *.: ", "identical_positions": 587, "similar_positions": 138, "identity": "73.74%" }, { "cls_id": "homologset.agr.MGI:2136744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5E5-1", "uniprot_id": "PCDB4_HUMAN", "id": "Q9Y5E5-1", "name": "Protocadherin beta-4", "aln": "-----------------------------------MKKLGRIHPNRQVLAFILMVFLSQVRLEP-IRYSVLEETESGSFVAHLAKDLGLGIGELASRSARVLSDDDKQRLQLDRQTGDLLLREKLDREELCGPIEPCVLHFQVFLEMPVQFFQGELLIQDINDHSPIFPEREVLLKILENSQPGTLFPLLIAEDLDVGSNGLQKYTISPNSHFHILTRNHSEGKKYPDLVQDKPLDREEQPEFSLTLVALDGGSPPRSGTVMVRILIMDINDNAPEFVHTPYGVQVLENSPLDSPIVRVLARDIDAGNFGSVSYGLFQASDEIKQTFSINEVTGEILLKKKLDFEKIKSYHVEIEATDGGGLSGKGTVVIEVVDVNDNPPELIISSLTSSIPENAPETVVSIFRIRDRDSGENGKMICSIPDNLPFILKPTLKNFYTLVTERPLDRETSAEYNITIAVTDLGTPRLKTQQNITVQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGASDRGSPALSSEALVRVLVLDTNDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAA--PAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGDSGTGEFKFLKPIFPNLLVQDTGREVKENPKFRNSLVFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q5G2-1", "uniprot_id": "E9Q5G2_MOUSE", "id": "E9Q5G2-1", "name": "", "aln": "MSNTVKIPPKRESEFSVSKHLETATGLDASMHFLIMEKLGRIHLNRQVMAFIFMMVLVQVCSEPTIRYSILEETESGSFVAHLAKDLGLGARELAARSARVLSDDYKQRLLLDPETGDLLLREKVDREEVCSTVDPCVLHFQVTLEKPVQYFQRELLIQDINDHAPEFPDRELLLRIPENSQQGTQFSLNLAQDLDVGSNGLQQYTVSPNPYFHVLTQNNSKGKKYPELVQDRGLDREEQAELSLTLTALDGGSPPRSGTALVRILIMDINDNAPEFVNSPYEVQVLESSPPDSPVLTVLARDADAGNFGRVSYGFFQASDEIQQTFSINATSGDMRLKKKLDFEKIKSYHVEIEAIDGGGLSGKGSVTIEVVDVNDNAPELTISSLTSSVPENAPETIISIFRVGDRDSGENGKMVCSIPENLPFILKSTFKNFYTLVTESPLDRESRAEYNITIMVSDMGTPRLTTWHTIKVQVSDINDNTPAFTQTSYTMFVRENNSPALHIGTISATDSDSGSNAHITYSLLPPHDPELALSSLISINADNGQLFALRALDYEALQVFEFHVGATDGGSPPLSSQALVRVVVLDDNDNAPFVLYPMQNASAPFTELLPRAAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDVPKHRLLLVVKDNGEPQRSASVTLQVLLVDGFSQSYLPLPEVARDPAHEDEDVLTLYLVIALASVSSLFLLSVLLFVGVRLCRRAREVSLGGCSMPGEHFPGHLVDVSGAGTLSQSYQYEVCLRGDSGTGEFKFLKPMIP-----NAGIEIMESPHCRDSFVFN", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:****** ****:***:*:.* ** ** ****:******************** ***:********* **** ** :*********:****:*..::******** ** ***:** **********:* **:**:**:* **** ** *.* :*:**********:**:***.:**:**:*:*:*****:****: ******.*:****.************.:****************::** *****.** ***:: ***** ****** ****:*******:****** .:*:: ******************* *********:*.*********.*** *******:*******::****: **********:****:*******.*:********* *****: ******* *:*:*****.* :.*.*****:***:*********:*************::**** ***:**::*******:**.*.*:**:*******:*****:*******.***:***:* ***.***:*****:*** ***:******:**.*** ***:***************** *********:***********.**********:*******..****:::******* ***:.**:*********.******.* **: : * **:***:**********:******.******:* .*:* **:* **********:************* *************::* ::* *: *.*: *:*:**.", "identical_positions": 615, "similar_positions": 125, "identity": "73.83%" }, { "cls_id": "homologset.agr.MGI:2136745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWA5-1", "uniprot_id": "A0ABK0LWA5_RAT", "id": "A0ABK0LWA5-1", "name": "", "aln": "----METASEKRQVVFLTILLLLWKSDAETIRYSMPEETESGYLVANLAKDLGLRVGELATRGARIHHKGNKDLLQLDAETGNLILKEKPDREVLCRATEPCVLHFQIILENPVQFFQTELQLTDINDHAPEFPDRKMLLKISESAQPGTMFPLKAAQDPDIGSNAVQNYTVSPNLHFHVITHSRTDGRKYPELVLDRALDREEQPELTLTLIALDGGAPSRSGTTTVHIEVVDINDNPPKFDQSLYEVQIPENSPLNALVATVSARDLDAGIHGTVIYSLFQGGELSQPFEIDEVAGEIRLKGTLDFEATPYYNIEIVATDPGGFSGKCSVAIQVVDVNDNAPKLTISSLNSSIPENAPEAVVAVFSVSDPDSGENGRIVCSIQNELPFLLKPTFENYYTLVTERPLDRESRADYNITITVSDLGIPRLTTQHTIIVQVSDINDNAPAFNQTSYTLLVRENNSPALHIGTISATDSDTGANAHISYLLLPLYDMQLALTSLVSINQENGQLFVLRALDYETLQTFEFSVGATDHGSPALSSQALVRVVVLDDNDNAPFVLYPLQNASVPCTELLPRAAEPGYLVTKVVAVDCDSGQNAWLSFQLLKATEPGLFNVWAHNGEVRTTRLLSERDVPKHKLLLVVKDNGEHQRSATVTLHVLLVDGFSQPYLPLPEVARDPVQDDEDVLTLYLVIALASVSSLFLFSVLLFIGMRLCKRAREASLGVCSVPEGHFPGHLVDVSGTGTLSQSYQYEVCLTGDSGTGEFKFLKPMISNLMVQDPGREVKESPPCRDSFVFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VE5-1", "uniprot_id": "Q91VE5_MOUSE", "id": "Q91VE5-1", "name": "", "aln": "MEMTLAKTPENRQVLFFTILLLLWKSCADAIIYSIPEETESGYLVANLAKDLGLRVGELAIRGARIHYKGNKELLQLDAETGNLFLKEKPDREVLCRATEPCVLHFQIILENPVQFFQTELQLTDINDHSPEFPDRKMLLKIPESAQPGTTFPLKAAQDPDIGSNAVQNYTVSPNLHFHVVTLSRSDGRKYPELVLDRALDREEQPELTLILTALDGGAPPRSGTTEVHIEVVDINDNAPQFIQSLYEVQILENSPLDALVATVSARDLDAGIYGKVAYSLFQDDGISQPFVIDEITGEIRLKGALDFEATPYYNMEIVATDPGGFSGKCTVVIQVVDVNDNAPKLTISSLNSSIPENAPETVVAVFSVSDPDSGENGRMVCSIQNELPFLLKSTFENYYTLVTEGTLDRESKAEYNITISVTDLGTPRLTTQHTITVQVSDINDNAPTFTRTSYTMFIRENNSPALHIGTISATDSDAGSNAHITYSLLPPHDPQLTLTSLVSINEDNGQLFALRALDYEALRAFEFHVRATDRGSPALSSQALVLVVVLDDNDNEPFVLYPLQNSSAPCKELVPRAAEAGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDAPKHRLLLVVKDNGDPPRSASVTLHVLLVDGFSQPYLPLSEVVQDPAQEGDDALTLYLVIALASVSSLFLISVLLFVGMKLCKRARSPSLGVCSVPEGHFPGHLVDVSGTGTLSQSYQYEVCLSGDSGTGEFKFLKPMISNLMVQDPEREVKESPHCRDSFVFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5E4-1", "uniprot_id": "PCDB5_HUMAN", "id": "Q9Y5E4-1", "name": "Protocadherin beta-5", "aln": "METALAKTPQKRQVMFLAILLLLWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVMCGATEPCILHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPESTQPGTVFPLKIAQDFDIGSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVVVSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIVATDGGGLSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAA--PAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYHYEVCLTGDSGAGEFKFLKPIIPNLLPQGAGEEIGKTAAFRNSFGLN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.::***:*::******:: :::: **:******** ********** ***** ****:*:****:***** :****:* ** ****:* *****:****::**********:*********:****:::*****.**:**** **** *** *****:*****:*** **** * .* ***********:******:***:* * *******.***** ::* *:* ***.*:* **:****: *****::**..********* :*.* *:***.. ::*** *** :.***** :**********:****** **:****:*.*:*********:**:*:*.*. ******:*************:***::*****:******.*::*:*****: .*****:*:*****:*:*:* ***.*:*.* * ***:*****:*.:****:::***********::**** *:*:**:::* *** : :* *:****** :**:**.**:****:*::*** * ***:*******:*** *:*** *** *********.*.**.**:*****.*********** *********:***********.:*********:*******..**:*:::*****: ***:.*****************.*.. *.* * **:***:**********:*****:.::**:*:* ..:* ****** ******************:*****:****:********:*.**: *.. .*: ::. *:** :.", "identical_positions": 561, "similar_positions": 166, "identity": "70.39%" }, { "cls_id": "homologset.agr.MGI:2136746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5E4-1", "uniprot_id": "PCDB5_HUMAN", "id": "Q9Y5E4-1", "name": "Protocadherin beta-5", "aln": "METALAKTPQKRQVMFLAILLLLWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVMCGATEPCILHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPESTQPGTVFPLKIAQDFDIGSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVVVSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIVATDGGGLSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADS--LTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYHYEVCLTGDSGAGEFKFLKPIIPNLLPQGAGEEIGKTAAFRNSFGLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91UZ8-1", "uniprot_id": "Q91UZ8_MOUSE", "id": "Q91UZ8-1", "name": "", "aln": "METALAKMPEQRQVFFLTILLLLWKSGSGATRYSMPEEKESGYLVANVAKDLGLRVGELATRGAQIHYKGNKELLQMDAETGNLFLKEKLDREALCGATEPCVLHFQVILENPVQFFQTELQLTDINDHSPEFPDREMLLKIPENAQPGTVFPLKAAQDSDIGSNAVQNYTVSPNIHFHVITHSRSDGRKYPELVLDRALDREEQPELTLILTALDGGAPPRSGTTIVHIEVVDINDNAPQFIQSLYEVQILENSPIDTLVVTVSARDLDSGIYGNVAYSLFQGDGLSQPFVIDEVTGEIRLSKELDFEGISHYNIEIAATDGGDLLGKCTVVIQVLDVNDNAPELMIRKLTVPVPENSAETVVAVFSVSDSDSGDNGRIVCSIQNNIPFLLKPTFENYYTLVTEGPLDRESRAEYNITITVWDLGTPRLTTQHTITVQVSDINDNAPAFTQTSYTLFVQENNSPALQIGTISATDSDSGSNAHITYSLLLPQDPQLALASLISINPDNGQLFVLRALDYESLQAFEFRVGATDQGSPALSSQTLVRVVVLDDNDNAPFVLYPMQNASAPCTELLPREAESGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDVPKHRLLLLVKDNGEPQLSASVTLQVLLVNSFSQPYLSLPEVAQDPIQEDGEMLTLYLVIALASVSSLFLLSVLMFVGMRLCRRAREASLGVCSVPEGHFPGHLMDVSGTGTLSHSYQYDVCLSGDSRTGEFKFLKPMIPNVMVQEAGREVKENPPCRDSFVFS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *::***:**:******::** *.***:***.**** ***:****** *********::**********:* :****:* ******.:*******:****::**********:*********:****::********.:********* *** *****:*****:*** **** **.*.***********:******:***:* *************** ::* *:* *****:*:**:****: ****:::***.*******:* **.***:***** ::******* *.****.: ****. .:**:**.*****.* *****.*:*:********* : .*: *.***:.***********.*******::*****::*******::*:*****: .*****:********* *:*****.*:*.*** ***:****************:*******:**::**** ***:**::***** **:*:* ****:***.***:**.**:****:************:*******::****:*** ***:******:**.*******:** **.*********** *********:************:*********:*******..****::******** **:.**:****:.******.***.* * *. **:***:**********:***:**.:*****:* *.:* ****** *****:*********:**:*:***:*** :********:***:: * **.*: :... *:** :.", "identical_positions": 597, "similar_positions": 149, "identity": "74.91%" }, { "cls_id": "homologset.agr.MGI:2136756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UN67-1", "uniprot_id": "PCDBA_HUMAN", "id": "Q9UN67-1", "name": "Protocadherin beta-10", "aln": "---------MAVRELCFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPK--EPCMLYFQILMDDPFQIYRAELRVRDINDHAPVFQDKETVLKISENTAEGT-AFRLERAQDPDG-GLNGIQNYTISPNSFFHINISGGDEGMIYPELVLDKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSPIGFLIVK---VWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELVNS-YKINIQAMDGGGLSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHLLLVDGFSQPYLPLPEAAPAQAQAEADLLTVYLVVALASVSSLFLLS--VLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVRGAETLSQSYQYEVCLTGGP-GTSEFKFLKPVISDIQAQGPGRKGEENSTFRNSFGFNIQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y5E1-1", "uniprot_id": "PCDB9_HUMAN", "id": "Q9Y5E1-1", "name": "Protocadherin beta-9", "aln": "---------MKTRGFSFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPK--EPCMLYFQILMDDPFQIYRAELRVRDINDHSPVFRHKEMVLKISENTAEGT-AFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQAPENSPVGSLIVK---VSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELVNS-YKINIQAMDGGGLSARCTVLIKVLDSNDNPPELIISSLSNSVAENSPGIVLAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVTDLGTPRLKTEHSITLQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQ--ADLLTVYLVVALASVSSLFLLS--VLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVSGTGTLFQSYQYEVCLTGGS-ETGEFKFLKPITPHLPPHRGGKEIEENSTLPNSFGFNY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91Y02-1", "uniprot_id": "PCDBI_MOUSE", "id": "Q91Y02-1", "name": "Protocadherin beta-18", "aln": "---------MAARGSCVSRQRQVLFLFLLGGLCLAGSELGRYSVTEETERGSFVANLAKDLGLGVEALAAKRTRVVCDDNKQHLFLDSHTGDLLTNEKLDREKLCGPT--EPCMLYFQILMDNPFQIYRAELRILDINDHSPIFQDKKMILKILENTAVGT-TFRLERAQDSDG-GRNGIQNYTISPNTFFHITVHNSDEGMIYPELVLDKALDWEGQPEFSLTLTALDGGSPPRSGTATIHILVLDINDNAPQFPQELYEIQAPENSPIGLVVIK---VTGEDVDSGVNAEISYSFFDASEDIRATFQINPFSGEITLKALLDYEFIKS-YKLNVQAVDGGGLSARCTVLVRVLDVNDNAPELIMSSLVNEVVENSPETVLAVFRINDRDSGENGKMVCHIQENLPFLLKPSVDNFYILMTEGALDRESRAEYNITITVSDLGTPRLTTQHTIRVQVSDINDNAPAFNQTSYTLFVRENNSPAMHIGTISATDSDAGSNAHITYSLLPTQDLQMTLTSLVSINADNGQLFAIKALDYEALQAFEFHVGATDRGSPELSSQALVRVVVLDDNDNAPFVLYPMQNASAPYTELLPRTAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDVPKHRLLLLVKDNGDPPRSASVTLQVLLVDGFSQPYLPLPEVAHNPTQGEEDVLTLYLVIALASVSSLFLLS--VLLFVGVRLCRRARAASLGGCSVPEGHFPGHLVDVSGTGTLSQNYQYEVCLMGGSSGTSDFKFLKSIYPEVHAYSSQDNSDGNPTF---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4LHM7-1", "uniprot_id": "A0A0B4LHM7_DROME", "id": "A0A0B4LHM7-1", "name": "", "aln": "MRINHQWIYYAILSLCWFNKATLGAILDSRCYLEGGGSAESFLATEDLAVGSIIGKLRING---DANAETGDINLSLREKNAPVEIHPGTKELALSVELDKEGVRGPSSIYVNVICIRRHSTDPSFVIPVNVRVTDVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQFLNP---LEGTLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPKFQRESYSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTIVQSQD--AKYFRIHPHNGAISLLTPIGYADVANGATLVVKATQIDNPDRYALTTVQLTRPGSHSDLSTLAFVQKRFVMRIREDTAVGNRILALPTNKPGKHLKYVIPDPVNSQFFSVGSLGELVLAKPLDYEKMTKHEFQVLATDG---MTNSTAELTLEVIDVNDWEPRFRETHYEFMVPKS-SLQSRADSFEGVLIGKVEAADGDRNDKLELSLRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVHLIAIATDTGVPPRSTSVPVSVTMEG---------LTLARSGWNSNMLGMFGMIMGLFLMIIVALSCYIVR----SKKQGKSASSGLGLGRNRVHSQAHSSVSSANLVTHEKLAGNGNGNGASVTSGGVSVLHMKHGGNITMANPMNNGLHHVASGASSSMALGSSAALLERERERERDRERQRESYAATVRIFLPGIVSRASANGQLFEEDEIEHDSLQTENNNRKVAATGVASGGVTTISTTPANAGSNLLSATDAMGSSENNLTVYF------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: : :: .*. : .**: **:: :* : : .: ::: : :.. * :* . :**:* : **. :: :: :* : .::*: *:**::* : . *.: * *. ** :: **:*.* * . :* : ...: . . : ***.**** * ::::.* * * *:*.* . : ::::: * :*: *:* : *. : * :. * : :: : . * *.*: * :.*::.::.: *:*:*..* * * :.* : . .: ::* : .. . . . :.: ..:. :: . : .. . . :* :.: ** : :: : ** .: *: .** * ::::: : .:* .: : : * *:** * * :* * ::* :. * : .:.... . *. . . : :.*..*:: .. : . *: .:..: . *:* * * * .. * * : . .: ... . * * :: :**:. : * : *::..** : . : : * . ..:.:* :.** . *. .:: : .* *: : :. . ::: ** . . . . * .. :. .*. * . :: . * :. : . .. * . ..: . . * ", "identical_positions": 118, "similar_positions": 269, "identity": "14.39%" }, { "cls_id": "homologset.agr.MGI:2136761", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWS0-1", "uniprot_id": "A0A8I5ZWS0_RAT", "id": "A0A8I5ZWS0-1", "name": "", "aln": "MQHPGPRLWLMLQVMMGSCAAISS------MDLERPGDGKCQPVEIPMCKDIGYNTTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSP-IMEQFKFRWPDSLDCSKLPNKNDPNYLCMEAPNNGSDEPSRGSGMFPPLFRPQRPHSAQEHPLKDGGP---GRAGCDNPGKFHHVEKS-ESCAPLCTPGVDVYWSRDDKRFAVVWLAIWSVLCFFSSAFTVLTFLIDPSRFRYPERPIIFLSMCYCVYSVGYIIRLFAGAESIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGRKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLVPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGVFSLLYTVPATCVIACYFYERLNMDYWKMLATQHKCKTNNQTKTADCLMTTSIPAVEVFMVKVSMLLVVGITSGVWVWTSKTLQSWQQVCSRGLKRKS----RRKPASVVTSAGIYKKAQ--------HPQKPHLGKYELPAQPSACV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKG4-1", "uniprot_id": "FZD10_MOUSE", "id": "Q8BKG4-1", "name": "Frizzled-10", "aln": "MQHPGPRLWLVLQVMIGSCTAISS------MDLERPGDGKCQPVEIPMCKDIGYNTTRMPNLMGHENQREAAIQLHEFAPLVEYGCHSHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSP-IMEQFKFRWPDSLDCSKLPNKNDPNYLCMEAPNNGSDEPSRGSGMFPPLFRPQRPHSAQEHPLKDGGP---GRAGCDNPGKFHHVEKS-ESCAPLCTPGVDVYWSRDDKRFAVVWLAIWSVLCFFSSAFTVLTFLIDPSRFRYPERPIIFLSMCYCVYSVGYIIRLFAGAESIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLVPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGVFSLLYTVPATCVIACYFYERLNMDYWKMLATQHKCKMNNQTKTPDCLMTTSIPAVEVFMVKVSMLLVVGITSGVWVWTSKTLQSWQHVCSRGLKRKS----RRKPASVVTSAGIYKKAQ--------HPQKPHLGKYELPAQPSACV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULW2-1", "uniprot_id": "FZD10_HUMAN", "id": "Q9ULW2-1", "name": "Frizzled-10", "aln": "MQRPGPRLWLVLQVMG-SCAAISS------MDMERPGDGKCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSP-IMEQFNFKWPDSLDCRKLPNKNDPNYLCMEAPNNGSDEPTRGSGLFPPLFRPQRPHSAQEHPLKDGGP---GRGGCDNPGKFHHVEKS-ASCAPLCTPGVDVYWSREDKRFAVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSVGYLIRLFAGAESIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNMDYWKILAAQHKCKMNNQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQQVCSRRLKKKS----RRKPASVITSGGIYKKAQ--------HPQKTHHGKYEIPAQSPTCV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77438-1", "uniprot_id": "FRIZ3_DROME", "id": "O77438-1", "name": "Frizzled-3", "aln": "-MYAASILILHLTWAVATIAANGAGHNGPVASGAGPNGLQCQPIAVSACQGLGYNMTALPNLAGHTNQLEAELQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELMELWPSFLNCDGLP-QPEKHELCMQIPQEVAVPGGSPSGPPTTGSPGVEDHPQTYRFWKSGASPTSDLAGVLCPQNFSGSPFNPEECVPQCQR--DAFHTSSQKKTSETLILGLSAVCFVLTLFALVTFWAEPTRFGYPERPVLFLCLCYNLFSVCYLERIVFHNQARMHDVELQWRLMRPGCLLTPPCLASYITTSYLSLCAASWWLIFALCFYLSSHKKWSSEALEKRSGLFHVLAWVPPLAPPIAALLLEKVRPSELTGMCYAP--------GFVELPALVLLLLGLYFTLRASRSLLSLQQQLQP-TLAHHRFGQIRKRFVLFSLLYFAPTTAGVVAALCERY-------------ADSVPSCSTPDDCLSPTPLSAWPALVRIFFQLVGGTLTGLWVWSRKTCESYRNRLGASGTPTSSLMNQSKAAGALPKKHLYTSGKSMLPTGGITPLYAGISFHNVPVYNPNQSRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... * * * : :* .: . *.. :***: :. *:.:*** * :*** ** ** ** :*: ::.**:* ** : **:*** *:** :*. *:.**:::** .* :* :: **. *:* ** : : : ***: *:: : ** .. . *. : *.*.. . .* * :* . .*.* * *.: : .:*: : . : :.:**. : *:::** :*:** *****::**.:** ::** *: *:. :: * : : * :. * ::. *:.:.:: **::::* ::*:: :**. **:* .*. **: **. * . .* *::.:* .****:**. *** :* *::* * * . :*: ::: ::. .:: :: *: :**:** .*:*. :.. : ** .. . .* * ::.: :. :*:: : ** * :*:*:*: ** :*::: . . .* : *.*..:.. :*...: * . . :::*. . ", "identical_positions": 152, "similar_positions": 199, "identity": "25.04%" }, { "cls_id": "homologset.agr.MGI:2136772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920Q4-1", "uniprot_id": "VPS16_MOUSE", "id": "Q920Q4-1", "name": "Vacuolar protein sorting-associated protein 16 homolog", "aln": "--MDCYTANWNPLGDSAFYRKYELYSMDWDLKEELKDCLVAAAPYGGPIALLRNCWRKEKAAS-VRPVLEIYSASGLPLASLLWK--SGPVVALGWSAEEELLCVQEDGAVLVYGLHGDFRRHFSMGNEVLQNRVLDAR-IFHTEFGSGVAILTGAYRFTLSANVGDLKLRRMPEVPGLQSAPSCWTTLCHDRVPHILLAVG-PDLYLLDHATCSAVTPAGLAPGVSSFLQMAVSFTYRYLALFTDTGYIWMGTASLKEKLCEFNCNIRAPPKQMVWCSRP-RSKERAVVVAWERRLMVVGNAPESIQFVLDE-DSYLVPELDGVRIFSRSTHEFLHEVPVASEEIFKIASMAPGALLLEAQKEYEKESQKADEYLREIQELGQLIQAVQQCIEAAGHEHQPDMQKSLLRAASFGKCFLDRFPPDS--FVHMCQDLRVLNAIRDYHIGIPLTYTQYKQLTIQVLLDRLVLRRLYPLAIQICEYLRLPEVQGVSRILAHWACYKARAW-DMRDEDVARAINQKLG---DTPGVSYSDIAARAYGCGRTELAIKLLEYEPRSGEQVPLLLKMKRSKLALSKAIESGDTDLVFTVLLHLKNELNRGDFFMTLRNQPMALSLYRQFCKHQELDTLKDLYNQDDNHQELGSFHIRASYAAEERIEGRVAALQTAADAFYKAKNEFAAKATEDQMR----LLRIQRRLEDELGGRFLDLSLHDTVTTLILGGHNKRAEQLARDFRIPDKRLWWLKLAALADLEDWEELEKFSKSKKSPIGYLPFVEICMKQHNKHEAKKYASRVG---PEQKVKALLLVGDVAQAAEVAIEHRNETELSLVLSHCTGATDGAIADKIQRARAQAQKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H269-1", "uniprot_id": "VPS16_HUMAN", "id": "Q9H269-1", "name": "Vacuolar protein sorting-associated protein 16 homolog", "aln": "--MDCYTANWNPLGDSAFYRKYELYSMDWDLKEELRDCLVAAAPYGGPIALLRNPWRKEKAAS-VRPVLDIYSASGMPLASLLWK--SGPVVSLGWSAEEELLCVQEDGAVLVYGLHGDFRRHFSMGNEVLQNRVLDAR-IFHTEFGSGVAILTGAHRFTLSANVGDLKLRRMPEVPGLQSAPSCWTVLCQDRVAHILLAVG-PDLYLLDHAACSAVTPPGLAPGVSSFLQMAVSFTYRHLALFTDTGYIWMGTASLKEKLCEFNCNIRAPPKQMVWCSRP-RSKERAVVVAWERRLMVVGDAPESIQFVLDE-DSYLVPELDGVRIFSRSTHEFLHEVPAASEEIFKIASMAPGALLLEAQKEYEKESQKADEYLREIQELGQLTQAVQQCIEAAGHEHQPDMQKSLLRAASFGKCFLDRFPPDS--FVHMCQDLRVLNAVRDYHIGIPLTYSQYKQLTIQVLLDRLVLRRLYPLAIQICEYLRLPEVQGVSRILAHWACYKVQQK-DVSDEDVARAINQKLG---DTPGVSYSDIAARAYGCGRTELAIKLLEYEPRSGEQVPLLLKMKRSKLALSKAIESGDTDLVFTVLLHLKNELNRGDFFMTLRNQPMALSLYRQFCKHQELETLKDLYNQDDNHQELGSFHIRASYAAEERIEGRVAALQTAADAFYKAKNEFAAKATEDQMR----LLRLQRRLEDELGGQFLDLSLHDTVTTLILGGHNKRAEQLARDFRIPDKRLWWLKLTALADLEDWEELEKFSKSKKSPIGYLPFVEICMKQHNKYEAKKYASRVG---PEQKVKALLLVGDVAQAADVAIEHRNEAELSLVLSHCTGATDGATADKIQRARAQAQKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHG1-1", "uniprot_id": "VPS16_DROME", "id": "Q9VHG1-1", "name": "Vacuolar protein sorting-associated protein 16 homolog", "aln": "MPIMYNTGEWFKVRP-DYYRKVELATPDWPLDLDLEYMWVEVAPYGGPLAVTRDPTKLVPVKGNARPMIRIFDTTGREMGHILWN--HGKLIAMGWSDMEELICIQENATVFVYDMFGREKESYSIGDEASVTKIVEGK-VFQSSAGTGVAVMTTSGRVFLKQNS-SKTERKLPDIPNSSMNCSCWEIVTEGRNSYCLLGRDREVIKLFPGETVGTITANLFEKPHERIIKISVSYNHQHLALYTNTGLLWLGSVDMRQKYCEFDTGRKDMPLQMEWIMNSDNSEADAVVISYPSYLLIVNRNADRSDFPYDP-VMFLVAEMDGVRIITQSSHEIIQRLPKCVENIFAVNSQEPASYLFEAQKKFEEKSYKSDEYLSMCREK--IDLAVSECIEAASYEFCPETQKSLLRTAYFGKGFIRNHNPDE--YMRIMRILRVLNTLRHERIAMPITFKQFSHLNTEVILSRLVFRKHYAIAIQVAKHLNLPES----WILEHWAYHKVMN--DPNDTEVARKITEKFKNP-SVEGISFCNIASKAHQAGRDDLAIKLLELESRASLHVPLLLKMRKFDRAVGSATQSGDTELITQVLLEMKMHMMLSNLHMTIRDHPLALNIYKKIMRESNRAGLYGIYNTEDDQKAIAEYHFQN----AIETEGLESNLSMIGNAYAQGRCTLEAELCADTSR----LIKLQKTLSTKYNVSLNGLSIHETIQELLLIGELKEAERIRSEFKVPDRRFWWLRILTLSSQHKWEELEKLAKSKKSPIGYDPFVEVCLKQDNVMEARKYIPRCR---DNRRVVWYMRANLFNEAIDSAFEQRDVHSLFELQKNQAIVNNGTLLSKVCDCIAMLEGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03308-1", "uniprot_id": "VPS16_YEAST", "id": "Q03308-1", "name": "Vacuolar protein sorting-associated protein 16", "aln": "--MKNPSFDWERLKD-VFYRSRAIGELKWPTQYEEFKCALSLT----------------VIAVEIQDFIQVYNYFGQLLGKINLQRIHEDIIKFEFDKDEKLILVTKSSIKIVKGWSPLTIESVPLQDPTIDTIWDYHNGIMLLAKSRDIYKLNGNEWELLYENK--DKKYNLLTKNHWSCNDDSIILLDVDHVYQVSTSNG-ALLKLITDSSWHKVTIS------SRGFICLYNMKDNKLQIFRDPARILM------------EHNLDSTPDDICWCGND------TVACSFEDEIKLYGPDGLYVTFWYPFTVTNLRAEVDGLKVITTEKIYFLSRVQPQTSNIFRIGSTEPGAMLVDSFSLLEDHAPKAIEILKN----FVLEKGVLDCIAAAIDEFEPKLQKMLLNAASYGKASLQYKSFDASIFVNACNTIKLLNCFR--SFGIFLTVEEYRCISLKGVIDRLLKYHRYYECIQICKLANERFLLG--YVFTEWAKDKIKGSPDMEDDELLDKIKSRLSVIDMTDTLQMVAVAKVAYLEGRFQLSRNLALLEKNEEARIEQLYNLDDDSIALKECIKVQNYSLTISLLIALSKKLTNSQLTKLLIIDMFNNPLYLYYMR-MDKAYLYDFYRQTDRFIDLAHVLLQQ----GKEQQSLHSFLPQIKDLYSQVQNSEVVNNTIEQLQRQEKLWIYQESLGKRFAISFTNMTLDQTLSKLIETGQDKQVKEIVKKFKISEKKLYHLKCKTLVEAKKFDELLQFAQSRKSPIGYMPFYTYLKSRGHMDKASPYVNMIPGLSYQEKKKLYVECRGFRDAIQLAGKEKDIPGLKEIYN-IIPPNEPELKALANETMSRI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :* : :**. : .* . : : : : .: ::. * :. : : :: : :. *:*: : :.. :* . . .: : . . . :: . .: :. * * . .: . .. : .: . . : *: : :* . : . . . * :: :.. : : : . * :: * . :*. :: : : . * * .*:**::::: .. :: .: .:** : * *.: *.:: . *..: *: * * : .* :** ** *. *. ** **.:* :** : * ::. . :::** .* :.: :* :: :. : ::.**: : * .**:.: . :: .** * * * :: *..:: . :. :* *: ** :*: :* * . :: * :: . *: .. : : .* :*: :. .: .:: : . : :* : : * .:*. * :. :: . :. : * : : : : .: : : * *. * . : .:::.:*: *: *. *..:.: .*::.::::: *: :* . ..::** ::::*:****** ** .: : :* * :.: : . :* : * :.:: * : . .: : ", "identical_positions": 102, "similar_positions": 271, "identity": "11.85%" }, { "cls_id": "homologset.agr.MGI:2136773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJW5-1", "uniprot_id": "A0A8I6GJW5_RAT", "id": "A0A8I6GJW5-1", "name": "Pre-mRNA-splicing factor CWC22 homolog", "aln": "---------------------------------------------------------------------------------------MKSSMAHMKQSSGHDRRES------------------------------HNSYHRRSSSPEDR--------------------------------------------YTEQDRSPRDRD----YSDYS----------------RSDYERSRRGYS-------------YDDSMESRSRDREK-----------RRERERDADHRKRSRKS------------------------PSPERRSPDRGVSQSS------------------------TQEEPTSKKK---KDEQDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASP--IFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKVIKKEILDEGDSDSNTDQEAGSSEDEEEDEEEEEG-EEEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQY-DTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDAEQ----------------KKPVLTSSSSESSSG-SDSSDSDSDSSESSSESSSEASDSSSSSS-QSSAS------AKGSRKKRQGKARGEEVDKLARSHQARDR-------RREGGREDQRHQEGRTERAR-SERHRAQHSRDADWRDPPAKHMEDR--------------------------------------------------------SHENSYNRVGNGREQGSHR-EPEDRHGEPRKKRRERR-DSFSENEKQRARNQDSD---------NVRR-KDGSKSRER--------------------------------SRKHSGHKGDDDDRYQNG-------------AERRWEKPSRYAEHSRESKRSQDR----------------------RREKSPTKHK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5N3-1", "uniprot_id": "CWC22_MOUSE", "id": "Q8C5N3-1", "name": "Pre-mRNA-splicing factor CWC22 homolog", "aln": "---------------------------------------------------------------------------------------MKSSVAHMK-SSGHNRRET------------------------------HSSYRR-SSSPEDR--------------------------------------------YTEQERSPRDRG----YSDYS----------------RSDYERSRRGYS-------------YDDSMESRSRDREK-----------RRERERDADHRKRSRKS------------------------PSPDR-SPARGGGQSS------------------------PQEEPTWKKK---KDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASP--IFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEDEEEEG-EDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQY-DTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQ----------------KKPALTSSSSESSSA-SDSSDSESDSSESSSESSSDASDSSSSSSTQSSTSGITAHSAKGTRKKRQGKARGEEVDKLARGHQALER-------RREGGREDQRHQEGRTERAR-SERRRAQNSRDADWRDPLAKHIDDR--------------------------------------------------------SHENSHSRVGNGREQGSHR-EPEDRHGEP-KKRRERR-DSFSENEKQRSRNQDSD---------NVRR-KDRSKSRER--------------------------------SRRHSGHKGDD-ARCQNS-------------AERRWEKPGRRPEQSRESKRSQDR----------------------RREKSPTTQK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCG8-1", "uniprot_id": "CWC22_HUMAN", "id": "Q9HCG8-1", "name": "Pre-mRNA-splicing factor CWC22 homolog", "aln": "---------------------------------------------------------------------------------------MKSSVAQIKPSSGHDRREN------------------------------LNSYQR-NSSPEDR--------------------------------------------YEEQERSPRDRD----YFDYS----------------RSDYEHSRRGRS-------------YDSSMESRNRDREK-----------RRERERDTD-RKRSRKS------------------------PSPGRRNPETSVTQSSS-----------------------AQDEPATKKK---KDELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASP--IFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAGSSE-EDEEEEEEEG-EEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQY-DTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQ----------------NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISS-HSSAS------ANDVRKKGHGKTRSKEVDKLIRNQQTNDR-------KQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVP-----------------------------------------------------SERNNYSRVANDRDQEMHI-DLENKHGDPKKKRGERR-NSFSENEKHTHRIKDSE---------NFRR-KDRSKSKEM--------------------------------NRKHSGSRSDE-DRYQNG-------------AERRWEKSSRYSEQSRESKKNQDR----------------------RREKSPAKQK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08C72-1", "uniprot_id": "CWC22_DANRE", "id": "Q08C72-1", "name": "Pre-mRNA-splicing factor CWC22 homolog", "aln": "------------------------------------------------------MAAESNDSQKAMNLGPTLRDEPPST------EEIEQRQRKASTSSSEDGEHE------------------------------DNDRRRVVGSPGSRDGSPR---------------------------VGSPVARASPRAKRDQKSSDSDSD----SSDSDDGVMRKIRSSVMHIRRTSDEETKNRERSSSPD--------RHEKKSKSRSRSRSR-----------SRSRSRSRSPRERYRRARRSRERERDRYGDRERYERR----SSRERDWEHRRRGRSASPDKN----------------DKPPTEEPPVKKR---KETLDPILTRTGGAYIPPAKLRMMQAQITDKSSLEYQRMSWEALKKSINGLINKVNVSNIANIIQELLQENIVRGRGLLARSILQAQAASP--IFTHVYSAVVAIINSKFPQIGELILKRLILNFRKGYRRNDKQQCLTASKFVGHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAISFLKECGLKLTEVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAIRKDGFKDHPIIPEGLDLVEEEDQFTHMLPLEDEYNTEDILNVFKLDPNFLENEEKYKTIKREILDEGSSDS-GDDAGGSGDDEDDDEEDEEA-AAGEEQEKVTIFDQTEVNLVAFRRTIYLAIQSSLDFEECAHKLIKMDFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCLLKKEYMESFEAIFQEQY-ETIHRLETNKLRNVARIFAHLLYTDSVPWSVLECVRMSEDTTTSSSRIFVKILFQELCAYMGLPKLNERLKDTTLQPFFEGLFPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNAPKMIMTQNQEVES----------------SDSSSSSSSSSDSSS-SSGSSSESDSSESDSDSSSDSDSSSSSGS--SSDS-------DSRRKKASGKKKDKSKSKKS-SKAANQR-------SPLEERPTKRHENRRQDASKEDRRGSDKHNRDPQRRGQQDESPPAR---------------------------------------------------------PRGEPERIRGQKEPHRHAQDHQDRPTDSGRHKDDGK-NSRVNKDKDRRRSREKE---------PLRRSRDRSKSRER--------------------------------SRKE----MDSRDSYGNG-------------LER-ADKENRHSDRYKESRRKDDR----------------------RHR----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ87-1", "uniprot_id": "CWC22_DROME", "id": "Q9VJ87-1", "name": "Pre-mRNA-splicing factor CWC22 homolog", "aln": "MGESDAESDSSSNSSSSDTSSGSDSDARSESSSSESSGREEEEAKQEESAKDAKKTDDTDRGEKRAKERDAGQDEQPTEQKKTPAAEPRSERQHISHSAGVEKQQEEAVAAAEAESEKLNEAKKVETPVQRKEEAEASSVTKELNSPKAQEENAARELEERRKDEEQPVTTNGSSKESPVEAAAETVKPPTADHIEEGEITDKDEDDLPTKEEKKAVASKSPPKETQRKQSRSPDGKRRRPRSSSRSPSPSSRRRRRSRSKGSRTRSRSKSPIRRRSNSLERRRVERQRRHEERDKRDEERAKEREKRHQKGEPTSSRRRDDSREKKRSPERKRDRSSSTPKSKSSKTPRHTETTETNADNETVTEPAAKITERQRKTVDVLTSRTGGAYIPPAKLRMMQSQITDKSSAAYQRIAWEALKKSIHGYINKVNVTNIAIITRELLRENIVRGRGLLSRSIIQAQAASP--TFTHVYAALVSIINSKFPNIGELLLKRLVIQFRRAFRRNDKMVCMSATRFIGHLVNQRVAHEILALEILTLLVETPTDDSVEVAIAFLKECGMKLTEVSSKGIGAIFEMLRNILHEGKLDKRVQYMIEVLFQIRKDGFKDHQAVVPELELVEEDDQFTHLMMLDEATETEDILNVFKFDDNYAENEDKYKGLSREILG---SDDGSSSGSGSGSDSDSDSDGESGSDAEKKAEAGDIIDSTETNLIALRRTIYLTINSSLDYEECAHKLMKMQLKPGQEIELCHMFLDCCAEQRTYEKFYGLLAQRFCNINKIYIPPFEEIFKDTY-QTTHRLDTNRLRNVSKFFAHLLFTDAISWDVLECIQLNEDDTTSSSRIFIKILFQELAEYMGLGKLNAKLKDDVLVESIAGLFPKDNPRNTRFSINFFTSIGLGGLTDDLRRFLKNAPKSVPAINAEILANAGGNPFRDGSAPAGNTKVAPSSSSSSSSSSDTDSEDSSEEDSSSDSSSESSSSDSSSEPKKKRKRKDKDKKKSKKATKEKSKKTKNKKKKKKAEKEQEKEKEKQRKSKKEKEKDKKRKKEEKKAAKKKSKHRRKSQESSDSSGSEDSDKSTSESSDSSNSSSDESDAEPQAKIKRQEHVEKNKFRGRTQDSDEFNLEGPGSKNRFQPNGNGQRRRDNSTGRERNRENSSYDRERNRGNSSYDRERKRGNSSYDRERNRESSYDKERKNRNAVAHDRQRKRDRSRSYERPTIRENSAPREKRMESSRSEKDSRRGDRSSRNERSDRGERSDRGERSDRGERSDRGERSDRGERSDRGERSDREKERSRAKERERDRDRDLKGQRERKRERDDGSRDRSRRERSSRRSKGRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53333-1", "uniprot_id": "CWC22_YEAST", "id": "P53333-1", "name": "Pre-mRNA-splicing factor CWC22", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTATIQDEDIKFQRENWEMIRSHVSPIISNLTMDNLQESHRDLFQVNILIGRNIICKNVVDFTLNKQNGRLIPALSALIALLNSDIPDIGETLAKELMLMFVQQFNRKDYVSCGNILQCLSILFLYDVIHEIVILQILLLLLEK---NSLRLVIAVMKICGWKLALVSKKTHDMIWEKLRYILQTQELSSTLRESLETLFEIRQKDYKSGSQGLFILDPTS-YTVHTHSYIVSDEDEANKELGNFEKCENFNELTMAFDTLRQKLLINNTSDTNEGSNS-----------------------QLQIYDMTSTNDVEFKKKIYLVLKSSLSGDEAAHKLLKLKIANNLKKSVVDIIIKSSLQESTFSKFYSILSERMITFHRSWQTAYNETFEQNYTQDIEDYETDQLRILGKFWGHLISYEFLPMDCLKIIKLTEEESCPQGRIFIKFLFQELVNELGLDELQLRLNSSKLDGMFP---LEGDAEHIRYSINFFTAIGLGLLTEDMRSRLTIIQEVEDAE----------------------------------------------------------------------------------------------EEEKKLREEEELEK-------LRKKARESQPTQGPKIHESRLFLQKDTRENSRSR--------------------------------------------------------------------------------------------------------SPFTVETRKRARSRTPP-------------------------------------------------------------------------------------------RGSRNHRNRSRTPPARRQRHR-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :... :** ** ::. : *.::.: *: ::*:: **: **.::.:.::: . : . :*:::::**.:*:*** : *.*:: * : :.*:* * . : :. *. * **:: *::* **:* :*:.:.*..:* ** **: ** : . *:* ** **: ::.. :: :*.:* :*:..:*. *: .. .** :.: :.:. *. *: *: * :. : :::* :* .. . * * *. * : :::.***.::***. :*.****:*:.: . .: .:::... :: *:.**:.:*: *: ::: : .:: *:: * : . :*::** :.:::.**: : :. . *: :::.*: : ...***:*::**** :** :*: :*:. * : ..:..: *::*****:**** **:::* *. : : . .* . :: : : : : : :.. . : ..: .: * .: .:. .* ", "identical_positions": 122, "similar_positions": 233, "identity": "9.13%" }, { "cls_id": "homologset.agr.MGI:2136782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6G2-1", "uniprot_id": "CF089_RAT", "id": "Q6P6G2-1", "name": "Bombesin receptor-activated protein C6orf89 homolog", "aln": "MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRGPPQYPLLIAMYKVLLTLGLILFTAYFVIQPFSSLAPEPVLSGAHTWRSLIHHIRLVSLPITKKYMPENKGVPLQGREEDKPFPDFDPWSSNNCEQNESEPIPANCTVCAQILPLKVTLPEDTPKNFERLRPLVIKTGQPLLSAEIQSFSCQYPEVTEGFTEGVLTKWWRCFPERWFPFPYPWRRPLNRSQILRELFPVFTQLPFPK--DASLNKCFLIQPEPVVGSKMHEVHDLFTIGSGEAMLQLIPPFQCRRHCQSVAMPIESGDIGYAGAAHWKVYIVARGVQPLVICDGTTLSEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KU6-1", "uniprot_id": "CF089_MOUSE", "id": "Q99KU6-1", "name": "Bombesin receptor-activated protein C6orf89 homolog", "aln": "MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRGPPQYPLLIAVYKVLLTLGLILFTAYFVIQPFSSLAPEPVLSGANSWRSLVHHIRLVSLPITKKYMPENKGVPLQGSQEDKPFPDFDPWSSYNCEQNESEPIPANCTGCAQILPLKVTLPEDTPKNFERLRPLVIKTGQPLSSAEIQSFSCQYPEVTEGFTEGFFTKWWRCFPERWFPFPYPWRRPLNRSQILRELFPVFTQLPFPK--DSSLNKCFLIQPEPVVGSKMHKVHDLFTLGSGEAMLQLIPPFQCRTHCQSVAMPIESGDIGYADAAHWKVYIVARGVQPLVICDGTTLSDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWU4-1", "uniprot_id": "CF089_HUMAN", "id": "Q6UWU4-1", "name": "Bombesin receptor-activated protein C6orf89", "aln": "MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRPPPQYPLLIVVYKVLATLGLILLTAYFVIQPFSPLAPEPVLSGAHTWRSLIHHIRLMSLPIAKKYMSENKGVPLHGGDEDRPFPDFDPWWTNDCEQNESEPIPANCTGCAQKH-LKVMLLEDAPRKFERLHPLVIKTGKPLLEEEIQHFLCQYPEATEGFSEGFFAKWWRCFPERWFPFPYPWRRPLNRSQMLRELFPVFTHLPFPK--DASLNKCSFLHPEPVVGSKMHKMPDLFIIGSGEAMLQLIPPFQCRRHCQSVAMPIEPGDIGYVDTTHWKVYVIARGVQPLVICDGTAFSEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QNX3-1", "uniprot_id": "CF089_DANRE", "id": "A4QNX3-1", "name": "Bombesin receptor-activated protein C6orf89 homolog", "aln": "MGSSLSEPCIYDKLSESIDILRQSGYRYGMSEREIEKFIKQVLETNEPRREPPQFPILRATVKFVVAVGVVLMAVLVFTYPQSPVLMGSVSGTTLNNSSPLSHIRLLELPIAEKYN-------LHG---------FHEWWASSSLQTMDLNCSA-CTDVTDILELTDQLRTSAG-EHTRTQPLLLKGGAALSLRVSQ--MDQFSSVSQTPAN--FTLLWSVSSR-------------PRESVLQWLFPESERCPLLEIWSSTLQRCRLSSRRPQP--SRVQVLGWMVVADGSPDVRLLPVQRCRKHCRSFSLRLEPGDMVFADSQIWLMELSPSGAQ-DVQCDSAVL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : .* .*******::*::**:*:: ****: *****:*:**.***:* ***:*:* . *.: ::*::*::. .. * *.: .* . : . * : ****:.***::** *:* *. * : .. *. . .* ** :: *. * .: :. * :**::* * .* * *:...:: :: :: * .. *..:*: *** : *: : .::*::* : .* . :: . : :..*.. ::*:* :** **:*.:: :*.**: :..: * : : . *.* * **.:.: ", "identical_positions": 95, "similar_positions": 119, "identity": "27.14%" }, { "cls_id": "homologset.agr.MGI:2136810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7J6-1", "uniprot_id": "LRFN1_RAT", "id": "P0C7J6-1", "name": "Leucine-rich repeat and fibronectin type III domain-containing protein 1", "aln": "MAPGPFSSGLLSPPPAALPFLLLLWAGASRGQPCPGRCICQNVAPTLTMLCAKTGLLFVPPAIDRRVVELRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQIRKVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFVQLHKLVRLDMTSNRLHKLPPDGLFLRSQGGG-PKPPTP--LTVSFGGNPLHCNCELLWLRRLTREDDLETCATPEHLTDRYFWSIPEEEFLCEPPLITRQAGGRALVVEGQAVSLRCRAVGDPEPVVHWVAPDGRLLGNSSRTRVRGDGTLDVTITTLRDSGTFTCIASNAAGEATAPVEVCVVPLPLMAPPPAAPPPLTEPGSSDIATPGRPGA---NDSATE-RRLVAAELTSSSVLIRWPAQRPVPGIRMYQVQYNSSADDSLVYRMIPSTSQTFLVNDLAAGRAYDLCVLAVYDDGATALPATRVVGCVQFTTAGDPAPCRPLRAHFLGGTMIIAIGGVIVASVLVFIVLLMIRYKVYGDGDSRRIKGTSRSPPRVSHVCSQTNGS--SAQQASAPPAPDRYEALREVAVPAA----IEAKAMEAEATSTELEVVLGRSLGGSATSLCLLPSEETSGEESRAVTGPRRSRSGALGPPTSAPPTLALVRGGSPARPRPQQRYSFDGDYGALFQSHSYPRRARRTKRHRSTPHLDGAGGGAAGEDGDLGLGSARARLAFTSTEWMLESTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2WF71-1", "uniprot_id": "LRFN1_MOUSE", "id": "Q2WF71-1", "name": "Leucine-rich repeat and fibronectin type III domain-containing protein 1", "aln": "MAPGPFSSGLFSPPPAALPFLLLLWAGASRGQPCPGRCICQNVAPTLTMLCAKTGLLFVPPAIDRRVVELRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQIRKVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFVQLHKLVRLDMTSNRLHKLPPDGLFLRSQGGG-PKPPTP--LTVSFGGNPLHCNCELLWLRRLTREDDLETCATPEHLTDRYFWSIPEEEFLCEPPLITRQAGGRALVVEGQAVSLRCRAVGDPEPVVHWVAPDGRLLGNSSRTRVRGDGTLDVTITTLRDSGTFTCIASNAAGEATAPVEVCVVPLPLMAPPPAAPPPLTEPGSSDIATPGRPGA---NDSTSE-RRLVAAELTSSSVLIRWPAQRPVPGIRMYQVQYNSSADDSLVYRMIPSTSQTFLVNDLAAGRAYDLCVLAVYDDGATALPATRVVGCVQFTTAGDPAPCRPLRAHFLGGTMIIAIGGVIVASVLVFIVLLMIRYKVYGDGDSRRIKGTSRTPPRVSHVCSQTNGA--GAQQASAPPAPDRYEALREVAVPAA----IEAKAMEAEATSTELEVVLGRSLGGSATSLCLLPSEETSGEESRAMTGPRRSRSGALGPPTSAPPTLALVPGGAPARPRPQQRYSFDGDYGALFQSHSYPRRARRTKRHRSTPHLDGAGGGAAGEDGDLGLGSARARLAFTSTEWMLESTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P244-1", "uniprot_id": "LRFN1_HUMAN", "id": "Q9P244-1", "name": "Leucine-rich repeat and fibronectin type III domain-containing protein 1", "aln": "MAPGPFSSALLSPPPAALPFLLLLWAGASRGQPCPGRCICQNVAPTLTMLCAKTGLLFVPPAIDRRVVELRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFVQLHKLVRLDMTSNRLHKLPPDGLFLRSQGTG-PKPPTP--LTVSFGGNPLHCNCELLWLRRLTREDDLETCATPEHLTDRYFWSIPEEEFLCEPPLITRQAGGRALVVEGQAVSLRCRAVGDPEPVVHWVAPDGRLLGNSSRTRVRGDGTLDVTITTLRDSGTFTCIASNAAGEATAPVEVCVVPLPLMAPPPAAPPPLTEPGSSDIATPGRPGA---NDSAAE-RRLVAAELTSNSVLIRWPAQRPVPGIRMYQVQYNSSVDDSLVYRMIPSTSQTFLVNDLAAGRAYDLCVLAVYDDGATALPATRVVGCVQFTTAGDPAPCRPLRAHFLGGTMIIAIGGVIVASVLVFIVLLMIRYKVYGDGDSRRVKG-SRSLPRVSHVCSQTNGAGTGAAQAPALPAQDHYEALREVESQAAPAVAVEAKAMEAETASAEPEVVLGRSLGGSATSLCLLPSEETSGEESRAAVGPRRSRSGALEPPTSAPPTLALVPGGAAARPRPQQRYSFDGDYGALFQSHSYPRRARRTKRHRSTPHLDGAGGGAAGEDGDLGLGSARACLAFTSTEWMLESTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGX3-1", "uniprot_id": "LRFN1_DANRE", "id": "Q6PGX3-1", "name": "Leucine-rich repeat and fibronectin type III domain-containing protein 1", "aln": "--------------MERLVFCVLVFGALAKAQLCPGRCICQTISPTLTLLCAKTGLLFVPPTVDRKTVELRLTDNFITAVRRKDFLNMTSLVHLTLSRNTISQIAPHAFMGLKSLRALHMDGNRLSVINSDQLKGLMNLRHLILGNNQIHHIEESSFDEFVATIEDLDLSYNNLRTLPWEAIARMTNINTLTLDHNLIDHIGVGTFTLLTKLVRLDMTSNRLQTLPPDTLFQHAQVLSEPKTSSSSRLTVSFGGNPLHCNCELLWLRRLTREDDLETCASPEHLMDKYFWSIQEEEFICEPPLITKHQVTKPYVMEGQGVTLKCKAMGDPDPAIHWRFPDGKLVHNNSRTILYDNGTLDILITTLKDSGAFNCVASNAAGIATAAVHVHMIPLPLLVNN-TGHMREADPGLSDISTSSRSSS---NDSKTHSKRVLVENLTAHSAVIHWPSERHIPGIRMYQIQY-------------------------------ELCVLAVYDDGITSLTATRVVGCVHFHTLPETNQCRFVPSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKAYSGGGGDTAKAKAGGDVSV-HVHSQTNGS------------------------------------------------------RSAATKQSEEPPESPAGKHCKALVLLK-----------MVLPILHLLF--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8WGA3-1", "uniprot_id": "LFN1L_DANRE", "id": "A8WGA3-1", "name": "Leucine-rich repeat and fibronectin type III domain-containing protein 1-like protein", "aln": "--------------MEWLIFSLLLLAVSASGQLCPKRCMCQNLSPSLAILCAKTGLLFVPTVIDRRTVELRLTENFITAVKRRDFANMTSLLHLTLSRNTISQIMPYTFADLKRLRALHLDSNRLSVITDDHFRGLTNLRHLILANNQLHNISPHAFDDFLGTLEDLDLSYNNLVDIPWDTIGRLTNVNTLNMDHNLIEHVPLGIFSNLHKLARLDMTSNKLKKIPPDPLFLRIPVYAKSKGSPLSSLVLSFGGNPLHCNCELLWLRRLTREDDLETCASPPDLTAKYFWTIPEEEFICDPPVITRKSP-KTFAMEGQPTSLKCKANGDPDPDVHWISPEGRLIANTSRTLSFSNGSLEINITSLKDTGIFTCIASNAAGESTGTVELVVSPLPHLANS-TNRIREPDPGPSDILTSAKSTSSVSNETRSQERKVVLAELSANSALIRWPSQQHFPGIRMYQIQYNSSVDDTLVYRMIPSTSFDFLVRDLVSGREYDLCVLAVYDDGVTSLTATRQVGCVTFVTETEFSQCQSLRSHFLGGTMIIIIGGIIVASVLVFIIILMIRYKVYSQHGADSGKG-----TAMTNVRSQTNGG--------------------------------------------------QAAGQVPRSSSKIVEGQEASGGSLGGAANIKDSTALVLVTDSETAVQISEISSEDIVSPTQR----------------HHPRTCIELKRRPSLSCKEGTSSDTQEDTASPQVSDEKKAQRDWSDFKI-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :*: . : .* ** **:**.::*:*::***********..:**:.******:***:**:*:** *****:*********.*: . :* .*: *****:*.***: : .*:::** *******.***::.:. :** *:.*:********** :**:::.::.*:***.:*****:*: * * * **.*******:*:.:*** ** : . .* .. *.:*****************************:* .* :***:* ****:*:**:**:: :. .:*** .:*:*:* ***:* :** *:*:*: *.*** .:*:*:: **:*:*:* *.*:****** :*..*.: : *** :. : .:** *** *..:. : *:: :. :::: :*:: *.:*:**::: .*******:** :********** *:*.*** **** * * : *: : ::******** ***:*********::******.*. .. *. : :* *****. . :. :..:* . . : . : : ", "identical_positions": 285, "similar_positions": 171, "identity": "36.59%" }, { "cls_id": "homologset.agr.MGI:2136825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT79-1", "uniprot_id": "D3ZT79_RAT", "id": "D3ZT79-1", "name": "NEDD4-binding protein 1", "aln": "---------------------------------MAARVVLDEFTAPAEKAALLERSRGRIEALFGVGLAVLGAL----GAEEPLPAR-IWLQLRGAQEAVHSAKEYIKGLCEPELEERECYPKAMHCIFVGAQSLFLKSLIQDTCADLCVLDTGLLGIRGSAEAVVMARSHIQQFVKLFESKESLPSHQKESEIKREFRQFVEAHADSYTMDLLILPTSLKKELLSLTQGEENLFETGDDDVITVGDVRPPEFTQSTAAGPSIARDDIVVQEESRNKARTPVSELT-KQMDTVFSSSPDVLFVPVNGLSPDEDALSKDRVCHKRRSSDTEERHTKKQFSLENVPEGELLQDGKASAENEVIDLSDAASNSTNLSPDGKDTTEEMEYNILVNFFKTMGYSQEIVEKVIREYGPSTEPLLLLEEIEKENKRLQEDRDFPPCTVYPEDSQSRSAGGRSTTNELTAESTPKKTQNHTEQTMVERFSQLPFK-DSKQCTSN--CRINSFKTVPVGQKHEIWAS-KQNSNCTVDLETDG--VLAASASPKDVSFVSRGALGHQQRNSAFLENGFQQQAEPLLPNNVKPACEKRSGGCGSPQPKPNYHPPLSPPLPPPQLLPSATEARLGGSSDHIDSSVTGVQRFRDTLKIPYKLELKNEPGRADLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVFVPQWRTRRDPNITEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIVTNDNFREFVTESVSWREIITKRLLQYTFVGDIFMVPDDPLGRNGPRLEEFLRKEVFLRDMQPLLNALPSVGTFDPGFRSPSTQVANTSHQPPSRIQTS-SNHWLPQQPHFTPLATLPSMQQNLPVPAQRSSAETSELREALLKIFPDSEQKLKIDQILVAHPYMKDLNALSALVLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A037-1", "uniprot_id": "N4BP1_MOUSE", "id": "Q6A037-1", "name": "NEDD4-binding protein 1", "aln": "---------------------------------MAARVVLDEFTAPAEKAALLERSRGRIEALFGVGLAVLGAL----GAEEPLPAR-IWLQLRGAQEAVHSAKEYIKGICEPELEEKECYPKAMHCIFVGAQSLFLKSLIQDTCADLCVLDTGLLGIRGSAEAVVMARSHIQQFVKLFESNENLPSNQRESEIKREFRQFVEAHADSYTMDLLILPTSLKKELLSLTQGEESLFET-DDDVITVGDVRPPEYTQSAATGPSSARDEVVVQEDSRNKARTPVSELT-KHMDTVFSSSPDVLFVPVNGLSPDEDALSKDRVCHKRRSSDTEERHTKKQFSLENVPEGELLPDGKGSAGNEVIDLSDPASNSTNLSPDGKDTTEEMEYNILVNFFKTMGYSQEIVEKVIREYGPSTEPLLLLEEIEKENKRLQEDRDFPPCTVYPDASQSRNAGVGSTTNELTADSTPKKAQSHTEQSMVERFSQLPFK-DSKHCTSN--CKVNSFRTVPVGQKQEIWGS-KQNSSCTVDLETDGHSASAASASPKDISFVSRGASGHQQRNPAFPENGFQQQTEPLLPNNTKPACEKRSGSCSSPQPKPNY-PPLSPPLPLPQLLPSVTEARLGGSSDHIDSSVTGVQRFRDTLKIPYKLELKNEPGRADLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVFVPQWRTRRDPNITEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIVTNDNFREFVTESVSWREIITKRLLQYTFVGDIFMVPDDPLGRNGPRLEEFLRKEAFLRHMQPLLNALPSVGTFDPGFRSPSTQVANNSHQPPPRIQTS-SSPWLPQQSHFTALATLPSMQQNPPLPAQRSSAETSELREALLKIFPDSEQKLKIDQILAAHPYMKDLNALSALVLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75113-1", "uniprot_id": "N4BP1_HUMAN", "id": "O75113-1", "name": "NEDD4-binding protein 1", "aln": "---------------------------------MAARAVLDEFTAPAEKAELLEQSRGRIEGLFGVSLAVLGAL----GAEEPLPAR-IWLQLCGAQEAVHSAKEYIKGICEPELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGIRGSAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSLKKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPVSELT-KQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLENVQEGEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLLLEEIEKENKRFQEDREFSAGTVYPETNKTKNKGVYSSTNELTTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSN--CRINTFRTVPIEQKHEVWGS-NQNYICNTDPETDGLSPSVASPSPKEVNFVSRGASSHQPRVPLFPENGLHQQPEPLLPNNMKSACEKRLGCCSSPHSKPNC-STLSPPMPLPQLLPSVTDARSAGPSDHIDSSVTGVQRFRDTLKIPYKLELKNEPGRTDLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVFVPQWRTRRDPNVTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIVTNDNFREFVNESVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQKEVCLRDMQPLLSALPNVGMFDPSFRVPGTQAASTSHQPPTRIQGAPSSHWLPQQPHFPLLPALPSLQQNLPMPAQRSSAETNELREALLKIFPDSEQRLKIDQILVAHPYMKDLNALSAMVLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVK9-1", "uniprot_id": "N4BP1_DANRE", "id": "Q1LVK9-1", "name": "NEDD4-binding protein 1", "aln": "MSTTRPLLGMKRITEVTCTEPPGGRQSPTASRAQPDSLTVDEFTVHEDKQTELKCSKPKVEQVFQVTFTIIGLLDH-TGAHGSKASRQIWLQLKGKKEDVYKAKEYVKGLCDPELQKEEWYPVDMHCIFAGARGLFLDRLLRDTSAEVQVLEPGRLKLSGCAEAVVMAQSRVQQFVALFQEKRSLPAD-REPSVKRKFKTFVEDRADKYAMELLLLPSALKEELLGLAQSP--------TQPIVIID-----------------------LEQDRSQTSTPVTDLSNRILDTTFEDKT-------SPITPEVMPGLNGRPCNKRRSSESEQRDTKRQYSLERREEEQCEEREREPTKTWTVKSAKGTLAASEMTNESEAVSPETNLRCLVNFFRTMGYQQDVVERVVRETGQTEDTFLLLERIVEETQKTQSTQGAQRTSRTPDPSPCANASSTSTSNRLKEK----------ERVQMRALAEIKCKENIRPPSTNGIGQKNQTSSVPLASATLKRNNGAQTDLCEVIIIDDEEDFTETERKPR----LTPLDLKPESRFDYLP----RGSSQTMVPVRMETVTNLRSSSQGPPLRTSDT----RPGCSYQTLPGRAPLPRSEAQYTSKAAPLTGMSRFQQSLRTPYRLILQNEPGSPNLRHIIIDGSNVAMAHGLHRVFSCRGIAIAVEAFWRRGHREITVFVPQWRQKKDPNITEQHFLNQLENLRLLSFTPSREVCGHRISSHDDRFLLHLAEKTGGVIVTNDNLRDFVSQSEAWRRIIHERLLQFTFVEDHFMIPDDPLGKHGPHLDEFLLKDSRG---SPIIPPLRTDLRATPSVYSQAAQSTAHPSSPSHWPHSG------PPDWHLPRPSPSP--------PPQRSPSETTELKRKLYDIFPD--QKQRIDRILSDNPYMRDLNALSGLLLG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W135-1", "uniprot_id": "Q9W135_DROME", "id": "Q9W135-1", "name": "RNase NYN domain-containing protein", "aln": "---------------------------------MSETNKNKDPTGTSLKKQPWHKRGSASAMASNILLQLAAEDPQR---------------DAYPKDTVIAAQETGASSSNTKMPKQAVKHKGFKKIRGPKPKNGQKRLKRN-----------------ATQKKALNREMVSKFLNSIKKKYALQKNHHIKRRLDFRRRESPEKKNALPKPKFYNPN----------------------------------------------------KNDNKKEEGEIVTELD---------------------SSDDDDCVLLDTPNESISILDDEDDEPSTSDQLLKQIVMDCN-------GEAALRITPKTENAVLYSTIGKQNSSDSIINLDDTFEAVPSLVVDSNDSVIYIEDTTGEDFIPIPSYSPPFREGEKQRRARPAKTPNKKTARMNDSFFTTE-----------------------------------------------------------------------------------------------------------------EKKKLGDYNTNTFNPTEEAGEASNKPKTNK------------------------------------------------------------RFVIIDGSNVAFAHGNSNVFSSEGIKYCLQYFEKMG-HEVKAVVPMFR-KNNFKSSNPELLDKLHKEGKIVFTPCKNIPGQITSSYDDRFILQLAYEKNAAVVSNDNYRDLINENPAFKLIVENRVLGYSWCDNIFILPKDPYGRWGPTLDEILRC---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: * * . : : : . :: * *:* . .:.:: :. :: * . * :: .:: .: :. :.:*: ::.: * : : : : . : *. :: :.: *::* : : .. : *: ... . .* . : : : : : : : : . .* . . : : *: . : : :: : :. :. : . . . . . :: . : : . :. . . .. ..: :.::*******::** ..**..** .:: * : * :::...** :* :.: : :: .:* :*.: : :**.: : *. :*:****:*:** :... :*:*** *:::.:. ::: *: :*:* ::: : *::*.** *: ** *:*:* ", "identical_positions": 65, "similar_positions": 181, "identity": "6.92%" }, { "cls_id": "homologset.agr.MGI:2136841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MIX0-1", "uniprot_id": "A0A096MIX0_RAT", "id": "A0A096MIX0-1", "name": "", "aln": "MAVQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTVNGHVPVGLYGNGFKSGSMRLGRDAMVFTKNGDTMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQ-MIYLTESKASLAAMLEHSLFSTEQKLLAELDAIMGK-----KGTRIIIWNLRSYKN-ATEFDFEKDKYDIRIPEDLDEVAGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGVIECNFLKPTHNKQDFDYTNEY-------RLTILALGEKLNDYWNEMKVKKNSEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGIDQ--LPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKT-------KEKFRIRQPEMLPRILPRINHEIVYQ-TSVSSPSFSPVKESVPRPHISEVASPFAARIINNHLVSAQPEPESNS--------------LKRRLSVRSSILNAKTR----------------------RLSNPPIENSSYK-NDDDED--VIILEENSTPKPAVDLDVRSDIEVKSEQSHAEQTGIEVELVSSPQPGVQASSTSTATSRCDQGTAASTQTEAPGLMVKKEES-----MEEDMDVRN--------------------GRAAL-SCVSAEVKV---------------QETSAESADAAGHQ------LQELRSELLLVTQER---DDYKRKCQVFADQIQVLQRRLLEMN----DQCVKKEMCHQSTEMD------AVFLLG--SVNGQSESPGHVGSQYQQALE---EIERLKKQCSALQHVKGECSQSSCTESKSEMDEMAVQLDDVFRQLDKCTIERDQYRSEVQLLEMEKS---HMHSRCEELKTEVEQLKSTS---QQAGADVSTSSSAEEAVS--YVDGES-------------LKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISSS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F7BJB9-1", "uniprot_id": "MORC3_MOUSE", "id": "F7BJB9-1", "name": "MORC family CW-type zinc finger protein 3", "aln": "MAAQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAMVFTKNGETMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQ-MINLTESKASLAAILEHSLFSTEQKLLAELNAIMGK-----KGTRIIIWNLRSYKN-ATEFDFEKDKYDIRIPEDLDETAGRKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTRTVRITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEY-------RLTILALGEKLNDYWNEMKVKKNAEYPVNLPVEDIQKRPDQTWVQCDACLKWRKLPDGIDQ--LPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTS------KERFRIRQPEILPRILPQINPELLYQ-TSVSSQSFSPVKESVPRPHLSEVTSPFAARIINLNLASPASEPENSS--------------MKRKLGVHSSILNAKTR----------------------RLSNPPVENSSYK-NDDDED--VIILEENSTPKPAVDLEVKSDIEVKSEQSHTEQSGIHVDLVSSPKPCVQASSTSTSTSRSDPGITVSTQTDAPGLTVKKEES-----MEEDMGVRN--------------------GTATL-SCVGTEAKV---------------QETSAESVDATSHQ------LQELRSELLVVTQER---DDYKRQCQMFTDQIQVLQQRLLEMN----DKCVKKEKCHQSTETD------AVFLLD--SVNGQAESLDHLGSQYQQALQ---EIERLKRQCSALQQVKSECSQASCTESKSEVDEMAVQLDDVFRQLDKCTIERDQYKNEVQLLEIEKS---HIHSQCEELQTEVEQLKSTG---QQAAADGSTASNAEEPVS--YVDGES-------------LKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14149-1", "uniprot_id": "MORC3_HUMAN", "id": "Q14149-1", "name": "MORC family CW-type zinc finger protein 3", "aln": "MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQ-MINLAESKASLAAILEHSLFSTEQKLLAELDAIIGK-----KGTRIIIWNLRSYKN-ATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQDFDYTNEY-------RLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGMDQ--LPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTN------KEKFRIRQPEMIP----RINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS--------------LKRRLSTRSSILNAKNR----------------------RLSS-QFENSVYKGDDDDED--VIILEENSTPKPAVD----HDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEET-----VEDEIDVRN--------------------DAVILPSCVEAEAKIH------------ETQETTDKSADDAGCQ------LQELRNQLLLVTEEK---ENYKRQCHMFTDQIKVLQQRILEMN----DKYVKKETCHQSTETD------AVFLLE--SINGKSESPDHMVSQYQQALE---EIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKS---QIRSQCEELKTEVEQLKSTN---QQTATDVSTSSNIEESVN--HMDGES-------------LKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U1B0-1", "uniprot_id": "A0AB32U1B0_DANRE", "id": "A0AB32U1B0-1", "name": "", "aln": "MAAQTERGILLSALNPKFLHTNSTSHTWPFSAIAELIDNAYDPDVSAKQFWIDKTAIRGEDCLIFMDNGSGMDNDKMFKMLSFGFSDKETINGHVPVGLYGNGFKSGSMRLGRDAIVFSKNKESMCVGLLSQTYLEAIQAENVIVPIVSFKRVGQSMLPEAQHAASLHDILQYSLFRTEAELLCELKAINAHYANECTGTRIIVWNLRKTSSGKSEFDFDIDRYDIQIPAEVYENEKEK-YKQPCRTFQSSPESDFSLRAYCSILYLKPKMQIILRGQKVKTQLISKSLAHIVKDKYKPNFLNERIPITFGYNTKSKEHYGVMMYHKNRLIKAYERVGCQNRANEKGVGVIAVIECNFLKPTHNKQDFDYTEEYREGYKQYRRTITTLGVKLEEYWKAIRHKKG--FDNNLPMEDIPKRPDQNWVQCDECLKWRKLPDGIDMNKLPDKWFCRMNPDPQFRRCEENEEAEDSADEASTCLKTYKEYERNLKRQQEQKKIKAEETRLRQEQQKNAELIKQNESLKRMHSSLVRQLHHNPPSSPRSPTVSWQAMSPHNSQTASSPSDNMPVISNVCSLSTPKRVKRPLSLSQSQTAKRARPHDDYSVNTPGSPSISAAALDVRTSPGNANNNVNISDDSSEDDDIVIDEVHSTPRPKPS---TFDLSKVKTEENNSDNAIELFMECSDQALVDTETEDTTKGPSTSEGQTNTTTQTECLSIKKEEDQQMQKKETEIKEENKNDPRAIKQSPGEVEGGIIKESMEVNTCSSSEVSRTNLDGIPKENSLSLEQQTKSDVLNQGSRQSPSTSLFPNIEIDLLPTSEAQKQQDNLLEILEATAQERDKFKEKVLEKEIQLLKLSIKKDHSHQCIQTDPSEDYKTLYLQANQSIQKLTEERDELKRKEEALLKGKAEKEAQDEVCRERLKAESEGHSSTANAFVDADDEMALQVDFLLSELDTRNAECQELKCKLESLEQEKASYKQLEKEVEELRKQKEQWSKANGDKNTSATQTCSASTAAVLVNGIKNDGESTERPAEGQNTGTPAKLRELRSNVARLLVTFVPALDLDQVNYDCEVIDEILNQVIQEISPSETSFT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*. ** **** *****************:************.***:*****.* .. ** * ***.** **:.********** *:*********************:**:**:** ::*.**:*******.*:**:*:****:*:: * *: :: *** :*::*** ** :**.**.** .: .*****:****. .. :****: *:***:** :: * .* **: * * :****:*************:****:*********:*****:* :* *:*:**.. : ****:* :.*:***:****:********:**** :**: ****:.:******************:** * ** :** **::**: :: **. : ***:*** *****.***** **********:* **:**:* *******.** **.**. .* ****: :*: :*: * : * *:: : ::. * :: . * : . : : :. : . ..*... :** *. .* : * * * :*. :*..** ::* * :***:* . *:. . :.: .: .:.: : . :. :: : .*:.. . . * *:. * :**** * :: .* : :* :*.. *:*. . : . * : ::. :** .:: : :: . . ::: . ::.::** : . :**: .**. : * :::* *:: :*. ..: : : *: * * .. * :.:.* ..: . . ****:*:* :: :**. . * :: : ::: ** **: ::... ***:.: ** ..:. : :.:: .::*. *. **** ***.** **.:**. :** ***:***** :*:****.**::::* .:: ", "identical_positions": 418, "similar_positions": 280, "identity": "38.28%" }, { "cls_id": "homologset.agr.MGI:2136853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9QJ44-1", "uniprot_id": "A0A8M9QJ44_DANRE", "id": "A0A8M9QJ44-1", "name": "", "aln": "--MILFRKFRVLILMVFLIACSMHIMIDLLPKLERRS---------GSACSCSHTPSEEPQN-WAKHRAKPGS---------ESGWPNKHTLRILQDFSNEPSSNLTSHSLEKM-MVGERAEALKRFE-------QLTGDERRLATRDSAFKNAAVKGS----RLSALFEHPLYTRPLPPLTDEDTLFNVNTDIRFDPKAAENPEWNGES--KDGDYAPTGEMSSDSYPNWLRFHIGINRYELYSRHNPVIDAMLKDLVSQRITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAYHLDRILDFRRVPPVAGRLVNMTKEIRDVTRDKKLWRTFFISPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLSLAKRRTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKHSHDELSILVPLSQCCRVKKSTHLRLQLVAKEEFKLSSLMEESLQTDTLSPILIRPHLEAMDRRLRLVLQVLADCIEKEGYSNVVEDDMGTEGMDTGTVPQR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B8M1-1", "uniprot_id": "A0A8M3B8M1_DANRE", "id": "A0A8M3B8M1-1", "name": "", "aln": "--MILFRKFRVLILTVFLIACTMHIMIDLLPKLEKRAAGSSSSAGGGSGCSCAHTPGEEPRS-WGKQRAR-AA---------DPGWPNKHSLRLLQDFSNEPNSNLTSQSREK---VTERAGSEK----------QGSGKRGLMREADSRQRRTDVRVSS---VLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAAGQQEWHNEGNVEEEEFSPPGEANSESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLDGQPSVHGGR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IXL6-1", "uniprot_id": "FA20C_HUMAN", "id": "Q8IXL6-1", "name": "Extracellular serine/threonine protein kinase FAM20C", "aln": "MKMMLVRRFRVLILMVFLVACALHIALDLLPRLERRGARPS----GEPGCSCAQPAAEVAAPGWAQVRGRPGEPPAASSAAGDAGWPNKHTLRILQDFSSDPSSNLSSHSLEKLPPAAEPAERALRGRDPGALRPHDPAHRPLLRDPGPRRSESPPGPGGDASLLARLFEHPLYRVAVPPLTEEDVLFNVNSDTRLSPKAAENPDWPHAG-AEGAEFLSPGEAAVDSYPNWLKFHIGINRYELYSRHNPAIEALLHDLSSQRITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRMVNMTKEIRDVTRDKKLWRTFFISPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSSHRILDVMDMTIFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILVPLQQCCRIRKSTYLRLQLLAKEEYKLSLLMAESLRGDQVAPVLYQPHLEALDRRLRVVLKAVRDCVERNGLHSVVDDDLDTEHRAASAR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5MJS3-1", "uniprot_id": "FA20C_MOUSE", "id": "Q5MJS3-1", "name": "Extracellular serine/threonine protein kinase FAM20C", "aln": "MKMILVRRFRVLILVVFLLACALHIAVDLLPKLDRRATRSS----GEPGCSCAQPAAEAAGPGWAQARSRPGE-----SAGGDAGWPNKHTLRILQDFSSDPASNLTSHSLEKLPSAAEPVDHAPRGQEPRSPPPRDPAHRPLLRDPGPRPRVPPPGPSGDGSLLAKLFEHPLYQGAVPPLTEDDVLFNVNSDIRFNPKAAENPDWPHEG-AEGAEFLPTGEAAVNLYPNWLKFHIGINRYELYSRHNPAIDALLRDLGSQKITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRMINMTKEIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGRPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGHRILDIMDMTVFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILAPLHQCCRIRRSTYLRLQLLAKEEHKLSLLMAESLQHDKVAPVLYQLHLEALDRRLRIVLQAVRDCVEKDGLSSVVEDDLATEHRASTER---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4VCL2-2", "uniprot_id": "FA20C_DROME", "id": "A4VCL2-2", "name": "Extracellular serine/threonine protein CG31145", "aln": "--MAVLRTMKLKERLVISLGATL-VLLTLLLIVDVQM---------DFGVANRHLLQQQHQKIRLGNDYDGGT--------GGGGMLHEFKRKFLQKSNASGSKEASTQAGASQ---------------------SGGATSGQDAAAGASGGAAGPGTS----------RSTSTRKPTPHDRYADLQKHLLSDEYSHVIVDNAPDVSRDN-PTLAEMLHR--KASANASNLERFQLRITKKELYGEQDTLVDAVLRDMIKLPIQHVVQKEGGTQLKLIIEYPNDIKALMKPMRFPREQQTLPNHFYFTDYERHNAEIAAFHLDRILGFRRAMPVAGRTLNITTEIYQLAEEN-LLKTFFVSPSLNLCFHGKCSYYCDTSHAICGNPDMLEGSFAAFLPNFESGNRKLWRHPWRRSYHKRKKAQWETDANYCALVRDIPPYDDGRRLYDLMDMAVFDFLTGNMDRHHYETFKVYGNETFPLHLDHGRGFGRPFHDELSILAPVLQCCLIRKSTLVKLLDFHNGPKPLSQLMSESLSQDPVSPVLWQPHLEALDRRTGIILQSIRDCIKRNPPGDVDGSETDVSS---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.* ::: *: :..:: : : ** :: : . : : : . * ::.. ::**. . . .: :::: . . .. . . . . * * :: :: . : . : .* :*:: *.: ***..::. : *:*:*: . * * *.********: : * :**:***: .***:* *:.***:*:*********:******.***. ***** :*:* ** :::.:: * :***:**: *:**:*:*****.*.**:**.** :***:*****:: .:*: **:************:**.*.:** *:: **** . *: *:***::**** ***********: :**:** :***:*****: ***:***.*: *** :::** ::* . : ** ** *** * : *:* : ****:*** ::*: : **:::: * .: . ", "identical_positions": 193, "similar_positions": 151, "identity": "32.6%" }, { "cls_id": "homologset.agr.MGI:2136878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB20-1", "uniprot_id": "D4AB20_RAT", "id": "D4AB20-1", "name": "Hexosyltransferase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHMKTRLLYASVLTMGALCLYFSMES---FQELP-----------------------------------------------------------------------------------------------------FVFKKSHGKFLQLPEIDCKQK--PPFLVLLVTSSHKQLAARMAIRKTWGRETSVQGQPVRTFFLLGSSDSTEDMDATALESEQH--RDIIQKDFKDAYFNLTLKTMMGMEWVYHFCPQTA--YVMKTDSDMFVNVGYLTELLLKKNKTTRFFTGYIKPHDFPIRQKFNKWFVSKFEYPWDRYPPFCSGTGYVFSSDVAIQVYNVSESVPFIKLEDVFVG-LCLAKLKIRPE-ELHTKQTFFPGGLRFSVCRFQKIVACHFMKPQDLLTYWQALETSKDEDCPAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI67-1", "uniprot_id": "B3GT5_MOUSE", "id": "Q9JI67-1", "name": "Beta-1,3-galactosyltransferase 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHMKTRLVYASILMMGALCLYFSMDS---FRELP-----------------------------------------------------------------------------------------------------FVFKKSHGKFLQIPDIDCKQK--PPFLVLLVTSSHKQLAARMAIRKTWGRETSVQGQQVRTFFLLGTSDSTEEMDATTLESEQH--RDIIQKDFKDAYFNLTLKTMMGMEWVYHFCPQTA--YVMKTDSDMFVNVGYLTELLLKKNKTTRFFTGYIKPHDFPIRQKFNKWFVSKFEYPWDRYPPFCSGTGYVFSSDVAIQVYNVSESVPFIKLEDVFVG-LCLAKLKIRPE-ELHTKQTFFPGGLRFSVCRFQKIVACHFMKPQDLLTYWQALENSKEQDCPAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2C3-1", "uniprot_id": "B3GT5_HUMAN", "id": "Q9Y2C3-1", "name": "Beta-1,3-galactosyltransferase 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFPKMRLMYICLLVLGALCLYFSMYSLNPFKEQS-----------------------------------------------------------------------------------------------------FVYKK-DGNFLKLPDTDCRQT--PPFLVLLVTSSHKQLAERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAETKEVDQESQRH--GDIIQKDFLDVYYNLTLKTMMGIEWVHRFCPQAA--FVMKTDSDMFINVDYLTELLLKKNRTTRFFTGFLKLNEFPIRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVASQVYNVSKSVPYIKLEDVFVG-LCLERLNIRLE-ELHSQPTFFPGGLRFSVCLFRRIVACHFIKPRTLLDYWQALENSRGEDCPPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLS8-1", "uniprot_id": "Q9VLS8_DROME", "id": "Q9VLS8-1", "name": "", "aln": "MAAMANLHNTRMLRFFLVLIVVILTIFIYASYSTTSTLTANHVHPAASPPQQLIGSHPGRQPMDQVPPVNSTDKEYNSPPGESSSKQQSVSSRHSQQLPPQQAEIHKRHPQHRLPTIDEDALLDGGSAGASPQVGGPDQTPNVMADELLEEQQYGQSVDGITGNINSSTNNNSSADTLAVKQSIPAQSPQQQLPQSQSQVQPGLSDADLLIPTSNLQKFIENADRILKNITSNSSTGNPSDMAQLNAVDGKLEVSGVESEKQEPESKVIQEIKEAKKEAAVPLPKSAKPPVPPVKTTKSKVPSAPVDPSKGVATETLYEPGHVDEEIDAERICPKGGEFIKLLVLISSAMSHDAARMSIRQTWMHYGTRR--DVGMAFVLGRGTNETINKALTQENFIY--GDLIRGNFIDSYNNLTLKTISTLEWADVHCPKAK--YILKTDDDMFINVPKLLTFLD-KHKDKRTIYGRLAKKWKPIRNKKSKYYVSVDQFAAGVFPSFTTGPAYVLTGDIVHELYVRSLKTVYLKLEDVFTTGIVAKSLNVKRV-QAN---EFVNRRISFNPCNIRNAISVHMIKSNEQFDLWKKLLDQTTKCK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLT0-1", "uniprot_id": "Q9VLT0_DROME", "id": "Q9VLT0-1", "name": "Hexosyltransferase", "aln": "MAG-------RLLRCILILILVSFTVFTYVSK---------------------VG------VMEKVDYFT-------------TAKPDVMSKNPAIQLVG--EAIRLRSFREPIKDFDDG----------------------------FAVQISGNSSEGNK-DIYTTIDGN-----INVADSIAAIRSRR--IDEEKLHDDGLDSKDILAKKS----------------------------VVLYSIDTEVPVR-------------------------MPLVK------------------------------TIYKPGHLDSEIDMERICPQKGLSTQLLVLITSSLRHSAARMSIRQTWMHYGSRR--DVGMAFVLGKGKNKSVKKAIDQEDFMY--QDLIRGHFIDSYNNLTLKTISLLEWADLHCPKAK--YVLKTDDDMFINVPKLLTLIS-TLKANRTIYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIVHALYVQSLNTAFLKLEDVFTTGIVAESLNIRRV-NVR---EMANTRTKFETCHIRDKITIHMVRNNEQFTLWNMLLDDTIKCDNQV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NDD2-1", "uniprot_id": "A0A8M1NDD2_DANRE", "id": "A0A8M1NDD2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MHMNSLLNQCTEISR-----------MCEVDVSSEPTSPTLCNESSDTYCHVDRWQKLRTAVR----------------------------------------------------------------------------------------------------------KLEFWENFTHELIGSGFFSKVYKVIHNTTRKVMVVKIYKNDVDQDSIVR--EISLLQKLSHPNIVRYLGICVKEDKLYPILEYVSGGCLEELLARQDVPLCWREKVDLASDITRGMIYLHYKNIYHRDLNSKNCLIRMTARGREALVTDFGLAREVVELPSKDRKLSLVGSAFWMAPEMLRGEPYDRKVDVFSFGIVLCEILARIPADPEILPRTQDYGLDVSAFRKMVSGCPQRLLELAASCCLLDAFRRPSFTELQDELGEIAESLETPHSELTTG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : :: .: : :: : : : *. *. : : : : .: * . . : :: .. . :: :: . : . : :. .. :* * : * * . *: . : : : *.: : . * : : . . : . ", "identical_positions": 10, "similar_positions": 61, "identity": "1.67%" }, { "cls_id": "homologset.agr.MGI:2136882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6S5-1", "uniprot_id": "GET1_RAT", "id": "Q6P6S5-1", "name": "Guided entry of tail-anchored proteins factor 1", "aln": "MSASETDRWAWLLVLCFVFGCNVLRILLPTLSSFIS-RVLQKDAEQESQMRAEIQSMKQELSTVNMMDEFARYAR----LERKINKMTDKLKTHVKARTAQLAKIKWFIS-VAFYVLQAALMISLIWKYYSVPVAVVP----SKWITPLDRLVAFPTR-------------------------VAGGIGVTCWILVCNKVVAIILHPFS----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0D7-1", "uniprot_id": "GET1_MOUSE", "id": "Q8K0D7-1", "name": "Guided entry of tail-anchored proteins factor 1", "aln": "MSASETDRWAWLLVLSFVFGCNLLRILLPSLSSFIS-RVLQKDAEQESQMRAEIQGMKQELSTVNMMDEFARYAR----LERKINKMTDKLKTHVKARTAQLAKIKWFIS-VAFYILQAALMISLIWKYYSVPVAVVP----SKWITPLDRLVAFPTR-------------------------VAGGIGITCWILVCNKVVAIVLHPFS----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00258-1", "uniprot_id": "GET1_HUMAN", "id": "O00258-1", "name": "Guided entry of tail-anchored proteins factor 1", "aln": "MSSAAADHWAWLLVLSFVFGCNVLRILLPSFSSFMS-RVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYAR----LERKINKMTDKLKTHVKARTAQLAKIKWVIS-VAFYVLQAALMISLIWKYYSVPVAVVP----SKWITPLDRLVAFPTR-------------------------VAGGVGITCWILVCNKVVAIVLHPFS----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRM0-1", "uniprot_id": "GET1_DANRE", "id": "Q6DRM0-1", "name": "Guided entry of tail-anchored proteins factor 1", "aln": "MAAG----FNWFLVLSSVFLCNLVKTFLPSISSFLS-KIFHKDADQEMEMRTEIQNMKMELSTISMMDEFARYAR----LERKINKMTDQLKTLVKSRTAQQAKMKWIVN-IAFYILQAALMISLILKYYADPVTVVP----SKWIAPLERLVAFPSG-------------------------VAGGVGITCWLVVCNKVVALILQAVS----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53192-1", "uniprot_id": "GET1_YEAST", "id": "P53192-1", "name": "Golgi to ER traffic protein 1", "aln": "--MHWAAAVAIFFIVVTKFLQYTNKYHEKWISKFAPGNELSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSENKAFQAHLHKLRLLALTVPFFVFKIMYGKTPVYKLSSSTSTLFPTFVSGVWSQGWLYVLLHPLRTISQKWHIMEGKFGASKFDDMALQSVSLGIWVWALMNVINGVEFIVKQLFLTPKMEAPASVETQEEKALDAVDDAIILD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: * : :*.* . . : *. : : * *:: :: .:*: . :::: * *:::**::.*:::: *: *: *:: . :.*:::: : : * : . ::.* . * :: .* *: *: : . : * * * :: : . ", "identical_positions": 25, "similar_positions": 66, "identity": "10.55%" }, { "cls_id": "homologset.agr.MGI:2136886", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PI8-1", "uniprot_id": "RTN4R_MOUSE", "id": "Q99PI8-1", "name": "Reticulon-4 receptor", "aln": "MKRASSGGSRLLAWVLWLQAWRVATPCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCNLPQRLADRDLKRLAASDLEGCAVASGPFRPIQTSQLTDEELLSLPKCCQPDAADKASVLEPGRPASAGNALKGRVPPGDTPPGNGSGPRHINDSPFGTLPSSAEPPLTALRPGGSEPPGLPTTGPRRRPGCSRKNRTRSHCRLGQAGSGASGTGDAEGSGALPALACSLAPLGLALVLWTVLGPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99M75-1", "uniprot_id": "RTN4R_RAT", "id": "Q99M75-1", "name": "Reticulon-4 receptor", "aln": "MKRASSGGSRLLAWVLWLQAWRVATPCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISYVPAASFQSCRNLTILWLHSNALAGIDAAAFTGLTLLEQLDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLVPLRSLQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCNLPQRLAGRDLKRLAASDLEGCAVASGPFRPFQTNQLTDEELLGLPKCCQPDAADKASVLEPGRPASAGNALKGRVPPGDTPPGNGSGPRHINDSPFGTLPGSAEPPLTALRPGGSEPPGLPTTGPRRRPGCSRKNRTRSHCRLGQAGSGSSGTGDAEGSGALPALACSLAPLGLALVLWTVLGPC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZR6-1", "uniprot_id": "RTN4R_HUMAN", "id": "Q9BZR6-1", "name": "Reticulon-4 receptor", "aln": "MKRASAGGSRLLAWVLWLQAWQVAAPCPGACVCYNEPKVTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRLAGRDLKRLAANDLQGCAVATGPYHPIWTGRATDEEPLGLPKCCQPDAADKASVLEPGRPASAGNALKGRVPPGDSPPGNGSGPRHINDSPFGTLPGSAEPPLTAVRPEGSEPPGFPTSGPRRRPGCSRKNRTRSHCRLGQAGSGGGGTGDSEGSGALPSLTCSLTPLGLALVLWTVLGPC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***************:**:***************************.****:************:******::************.** *********:*************: ***:**:***:***********:********************* ******:******************.****:****************:**:*********************** **:*.* ***:************************************.******.********.**:*****:**::*: *.: **** *.************************************:********************.********:** ******:**:**************************..****:*******:*:***:***************", "identical_positions": 419, "similar_positions": 45, "identity": "88.58%" }, { "cls_id": "homologset.agr.MGI:2136890", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58467-1", "uniprot_id": "SETD4_MOUSE", "id": "P58467-1", "name": "SET domain-containing protein 4", "aln": "MQRRRGRTERARKRRRR-SSGSRAVNESYRSEFIELRKWLKERKFE-DTDLVPASFPGTGRGLMS-KASLQEGQVMISLP-----------ESCLLTTDTV-----IRSSLGPYIKKWKPPVSPLLALCTFLVSEKHAG-------CRSLWKSYLDILP-----KSYTCPVCLEP-----EVVDLLPSPLKAKAEEQRARVQDLFTSARGFFSTLQPLFAEPVDSVFS--------YRAFLWAWCTVNTRAVYLRSRRQ-------ECLSAEPDTCALAPFLDLLNHSPHVQVKAAFNEKTRC------------YEIR--TASRCRKHQEVFICYGPHDNQRLLLEYGFVSVRNPHACVPVSADMLVKFLP-----AADKQLHRKITILKDHGFTGNLTFGWD-GPSWRLLTALKLLCLEAERFT-SWKKVLLGEVISDTNEKTSLGVAQKICSDVIEETHAVLRKVSDMKEGTVSLRSQLSLVEALRMEELRILQASAEILSGLLAPFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVD3-1", "uniprot_id": "SETD4_HUMAN", "id": "Q9NVD3-1", "name": "SET domain-containing protein 4", "aln": "MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQ-DSNLAPACFPGTGRGLMS-QTSLQEGQMIISLP-----------ESCLLTTDTV-----IRSYLGAYITKWKPPPSPLLALCTFLVSEKHAG-------HRSLWKPYLEILP-----KAYTCPVCLEP-----EVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSLQPLFAEAVDSIFS--------YSALLWAWCTVNTRAVYLRPRQR-------ECLSAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHS------------YEIR--TTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSREILVKYLP-----STDKQMDKKISILKDHGYIENLTFGWD-GPSWRLLTALKLLCLEAEKFT-CWKKVLLGEVISDTNEKTSLDIAQKICYYFIEETNAVLQKVSHMKDEKEALINQLTLVESLWTEELKILRASAETLHSLQTAFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVB0-1", "uniprot_id": "Q7KVB0_DROME", "id": "Q7KVB0-1", "name": "SET domain-containing protein 4", "aln": "----MGRTQRRRHQRAKKSDENSGS-------LHDLYVHLHSVGWQNHTHLSAQYYEQTGRGLCSKQKTFSPEDELIRLP-----------IGCLISIATLESDGPFKSLFDEELFDKDSRISFQALIACYILYHKHLQECTLG-THSSTYAAYLDTLP-----RCYSTPYFCSI-----PELQCLPESLLERTVAQNRQIRGYFEIIKNIVHKCDCCGKSYGQEIWT--------LADFKWAYFSVNTRSVHLSSRFLKKQSNYFQPLISGDTNLALAPFLDLFNHSDQVEITAGIEGPDYV------------LTLKSLPFSETKPYDQLFISYGALPNFKLLTEYGFWLRENKHDYFEVSLLDIEHMIKQNKELSTQTFHRNIFKFIREHNLNDQMFVHIDDGCSHNLRVVLHLIFKQQAYFPNILNQIAFGDAEQFQDVQPELSYLVEYKIKEYEIFGGELDKLPKLTESGAVARSYLQECIRYLVDFQSVHLAA------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03942-1", "uniprot_id": "RKM2_YEAST", "id": "Q03942-1", "name": "Ribosomal lysine N-methyltransferase 2", "aln": "---MEGKVDVLLTWLKKSDKFYIAPNISICESPETGRGIVLSHGSIRKNDIIVSVPSSKQLNFHTILYHISKFNKELNIPGITIDRKPINYEDNIIEAENKAWADPRYGLYSELSKEFLLSLSSFQLVSFYILVENFLLPKWTHNEIYSDWKPFFDVWPSMEELRSIPAIWNCDPNSRYHSLIEYLPAASRKHMARISGLVREDWETISEVVLKWNEIYGSLSCTKNSDKFTSDELFSLFVHVYFIINSRCLYAKIPLK---------IEDSPSNFTLVPYVDFMNHICESDLHCYPQLSPQLRSEGENIIGIGQFTIRCGDHLYDNINEELFLNYGAHSNDFLLNEYGFVVDGNKWNYLDISDEIIELIDD---------DKKEVKTFLLEHDYWGDYTINET-DISYRIFVALNYYVTRDERRVRKFIEGYISEDYFKPKISSVLKELLVSLTAKYTKTLSELTEKVSNLENNLCLQNLITIYKGYIKILTQHLQDLQS----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.. .. . : ...: . .: : :. : : :* . :: . . . . * :. ::: .:. * : .::: * :. . . :: ** . : :: : .. . : . : : .: :*:*.:: : . :*.*::*::** . :: . : :: . :::*: **. * *: **** * . :* : . .:: :*. : . . * .: ..*: . : :.: . .. * . * : : . : ", "identical_positions": 30, "similar_positions": 117, "identity": "5.87%" }, { "cls_id": "homologset.agr.MGI:2136910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AZ54-1", "uniprot_id": "HEMGN_RAT", "id": "Q6AZ54-1", "name": "Hemogen", "aln": "MDVRKDQSHLTLNQTPEAHVEKSHAPDIIGSWSLRNREQLKKRKAEAQGRQTSQWQLGEQKKRKYQRTGKGNRRGRKRQGNVEQKAESWSQ-TENERVQEVLVPAEEETEYSGNTATQALPLRASPTKAVPTEHCSEVPQESLQCQEITIQNHSQTHQRRDKAEALSPTTCQEIGVLQYSPKMCQDMAEPEARSPKMCQETAVPQTYSPKAHEDMAEYEALSPKMCRETPVPQYHSSKIPQDMTGPEALAPDMCQETTVSQNHSSKVPQDMAGPEALSLKMCQEPTVLQEHTLKICQDVARPDVLSSKTHQEMTVPKALPCITPGDAAGPEGCSPKTLPQS--------DVTPMSVTPGKNTSHPDLGTAVAEGCFSEAGECIVSEDISTKTHQEAVEPKFLSHKTYKEFTVPIVSSHKTIQESPGPEEYSPG--------------SRHEMS----------------------------GPEDLSIKTCKNRDGPKHSLPEGAQEVGGAQRQDPDAQDIEDAGAFSQD---LEEGNKADQDPETPAGPQGPQKICPENDVHSSALF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERZ0-1", "uniprot_id": "HEMGN_MOUSE", "id": "Q9ERZ0-1", "name": "Hemogen", "aln": "MDMGKGRPRLKLPQMPEAHPQKSCAPDIIGSWSLRNREQLRKRKAEAQGRQTSQWLLGEQKKRKYQRTGKGNKRGRKRQGNVEQKAEPWSQ-TERERVQEVLVSAEEETEHPGNSATEALPLVPSPTKAVPADQCSEAHQESIQCQERAIQNHSQTH--------LSPTTCQGIAVLQHSPKMCQDMAEPEVFSPNMCQETAVPQTYPPKALEEMAAAEPLSPKMC----------------------------QETTVSPNHSSKVPQDMAGPEALSPNMCQEPTVPQEHTLKMCHDVARPEVLSPKTHQEMAVPKAFPCVTPGDAAGLEGCAPKALPQSDVAEGCPLDTTPTSVTPEQTTSDPDLGMAVTEGFFSEARECTVSEGVSTKTHQEAVEPEFISHETYKEFTVPIVSSQKTIQESPEPEQYSPETCQPIPGPENYSLETCHEMS----------------------------GPEDLSIKTCQDREEPKHSLPEGAQKVGGAQGQDADAQDSENAGAFSQDFTEMEEENKADQDPEAPASPQGSQETCPENGIYSSALF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXL5-1", "uniprot_id": "HEMGN_HUMAN", "id": "Q9BXL5-1", "name": "Hemogen", "aln": "MDLGKDQSHLKHHQTPDPHQEENHSPEVIGTWSLRNRELLRKRKAEVHEKETSQWLFGEQKKRKQQRTGKGNRRGRKRQQNTELKVEPQPQ-IEKEIVEKALAPIEKKTEPPG-SITKVFPSVASPQKVVPEEHFSEICQESNIYQEN-------------------FSEYQEIAVQNHSSETCQHVSEPEDLSPKMYQEISVLQ--------------------------------------------------------DNSSKICQDMKEPEDNSPNTCQVISVIQDHPFKMYQDMAKREDLAPKMCQEAAVPKILPCPTSEDTADLAGCSLQAYPKPDVPKGYILDTDQNPAEPEEYN-ETDQGIAETEGLFPKIQEIAEPKDLSTKTHQESAEPKYLPHKTCNEIIVPKAPSHKTIQETPHSEDYSIEINQETPGSEKYSPETYQEIPGLEEYSPEIYQETSQLEEYSPEIYQETPGPEDLSTETYKNKDVPKECFPEPHQETGGPQGQDPKAHQEDAKDAYTFP---QEMKEKPKEEPGIPAILN---ESHPENDVYSYVLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Y2-1", "uniprot_id": "A0ACD6B6Y2_DANRE", "id": "A0ACD6B6Y2-1", "name": "", "aln": "------MEDPLEKEIPPTEIKDSDEGGIR--RRLRDRDLLKKRKAEAEEKATNQWVYGAQSIKRVKKRTTTGTPGRKGRPRKEPIVIAEDLGLAQEVDPSPITIPVTEPELPTIAEIEPLQPVEPQQELVPEEAISEKPQE-------------------------------EFLIEDLGPDEEEDMPQ---------------------------------------------------------------------------KNLVIDTGDDE------------------KPYNDVPEQ--------SSIAIPMFAPAPDSSQPDNLSLTENLLF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. :.. : **:*: *:*****.. : *.** * *. :: :: . . *** : . * . . .* . :. :.* . : : : . : ** : ** ** : : : ... :.:.: .:: * * * :*:.. .. ::* *. . :. . ", "identical_positions": 33, "similar_positions": 65, "identity": "5.81%" }, { "cls_id": "homologset.agr.MGI:2136934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZA8-1", "uniprot_id": "A0A0G2JZA8_RAT", "id": "A0A0G2JZA8-1", "name": "", "aln": "MSAVKIEEASVDKLK-IHLTATACLQEEDKGKVLQGKLLRSISPESRVKLHCCYGVVIVVLTVAVVALSVALSVRNKIPVMENCEPCSATCPSGWIGFGSKCFYFSEDVGNWTFSQSSCMALDSHLALFDSLEELIFLKRYKGPSDHWIGLHRASTKHPWIWADDTEYSNLVLIRGGGQCGFLSDNGISSGRDYTHRKWICNKSSSICKSKLGNVPRHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1T8-1", "uniprot_id": "CLC2H_MOUSE", "id": "Q8C1T8-1", "name": "C-type lectin domain family 2 member H", "aln": "MNAAKVETSSMGMLQRADLTAADCLQEGEMGKKIQGKCFRIISTVSPVKLYCCYG-VIMVLTVAVIALSVALSVRNKIPAMEDREPCYTACPSGWIGFGSKCFYFSEDMGNWTFSQSSCVASNSHLALFHSLEELNFLKRYKGTSDHWIGLHRASTQHPWIWTDNTEYSNLVLTRGGGECGFLSDNGISSGRSYTHRKWICSKFVSSCKSRVGSVPRHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHP7-1", "uniprot_id": "CLC2D_HUMAN", "id": "Q9UHP7-1", "name": "C-type lectin domain family 2 member D", "aln": "MHDSNNVEK--------DITPSELPANPG--------CLHSKEHSIKATLIWRLFFLIMFLTIIVCGMVAALSAIRANCHQEPSVCLQAACPESWIGFQRKCFYFSDDTKNWTSSQRFCDSQDADLAQVESFQELNFLLRYKGPSDHWIGLSREQGQ-PWKWINGTEWTRQFPILGAGECAYLNDKGASSARHYTERKWICSKS-----------DIHV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : .:*.: : :: . ..* :*:.**: * .: .***. . * ::**..**** ******:* *** ** * : ::.** ..*::** ** ****.******* * . : ** * :.**::. . *.*:*.:*.*:* **.* **.*****.* **", "identical_positions": 73, "similar_positions": 51, "identity": "33.33%" }, { "cls_id": "homologset.agr.MGI:2136940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM05-1", "uniprot_id": "PIAS4_MOUSE", "id": "Q9JM05-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFK----KIKELYETRYAKKSAEPGPQAPRPLDP-----LALHS-------MPRTPLSGPTVDYPVLYGKYLNGLGRLPTKTLKPEVRLVKLPFFN------MLDELLKPTELVPQSAEKLQESPCIFALTPRQVEMIRNSRELQPGV---KAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSS-ATNRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EGADEIEFLAEGSWR---------------------------------------------------------------------------PIRAEKEP-------------SCSPQGPILVLGTSDANGLAPASSTPGIGSGLSGP---------------GSAGSGAGAAGSLENGKTGADVVDLTLD--------------------------------------SSSSSEDEDEDEDDDEDEDE--GPRPKR-RCPFQKGLVPAC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFF9-1", "uniprot_id": "B5DFF9_RAT", "id": "B5DFF9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFK----KIKELYETRYAKKSAEPGPQAPRPLDP-----LALHS-------MPRTPLSGPTVDYPVLYGKYLNGLGRLPTKALKPEVRLVKLPFFN------MLDELLKPTELVPQSAEKLQESPCIFALTPRQVEMIRNSRELQPGV---KAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSS-ATNRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EDADEIEFLAEGSWR---------------------------------------------------------------------------PIRAEKEP-------------SCSPQGPILVLGTSDANGLAPASSTPGMGSGLSGP---------------GGAGGGAGAAGGLENGKTGADVVDLTLD--------------------------------------SSSSSEDEDEDEDDDEDDDE--GPRPKR-RCPFQKGLVPAC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N2W9-1", "uniprot_id": "PIAS4_HUMAN", "id": "Q8N2W9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFK----KIKELYETRYAKKNSEPAPQPHRPLDP-----LTMHSTYDRAGAVPRTPLAGPNIDYPVLYGKYLNGLGRLPAKTLKPEVRLVKLPFFN------MLDELLKPTELVPQNNEKLQESPCIFALTPRQVELIRNSRELQPGV---KAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSS-ATNRITVTWG-NYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAPYDQLIIDGLLSKILSEC---EDADEIEYLVDGSWC---------------------------------------------------------------------------PIRAEKER-------------SCSPQGAILVLGPSDANGLLPAPSVN--GSGALG------------------STGGGGPVGSMENGKPGADVVDLTLD--------------------------------------SSSSSEDEEEEEEEEEDEDEE-GPRPKR-RCPFQKGLVPAC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R4C4-1", "uniprot_id": "PIS4A_DANRE", "id": "F1R4C4-1", "name": "E3 SUMO-protein ligase PIAS4-A", "aln": "-------------------------------------MAAELVEAMNMVKSFRVSDLQTLLASMGRSKSGLKQDLVGRALRLVQTEYSPELLK----NVRQLYETRFPKASAWLAARRPETVAVNY---PALNS-------SPRGTGQG---------TDYLNGIP-KPAPPPAAEVKLVPLPFYH------NLETLLPPTELVAQNSEKLQESQCVFDLTPNQVDQIRNSSELRPGM---KSVQVVLRICYTDSIGVQEDQYPPNIAVKVNQSYCHVPGYYPSNKPGVEPRRPCRPVNITPWLHLST-VTNRVTITWG-NFGKRYSVAVYLVRVFTSGELFNQLKHCSVENPDRCRERIQDKLRFDPESEIATTGLRVSLICPLVKMRLGVPCRVLTCAHLQCFDAVFFLQMNEKKPTWTCPVCDKPAPFELLTIDGLLSEILKETP--EDVEEIEYLTDGSWR---------------------------------------------------------------------------PIRDDKEKERE-------RENSRTPDYPVVDICVPEANGHSPAHSGTN-QTGKSG------------------SGGASAGTGSTSGGSGGGTVVDLTLD--------------------------------------DSSEEEGGGGAEDSEETDDSQDSPAPKRGRYDYDKDLVTAY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F8W4B9-1", "uniprot_id": "F8W4B9_DANRE", "id": "F8W4B9-1", "name": "", "aln": "-------MISVVVEGLSLGLYFFSVYFTLIVLFIFEIMSTDVLEAAVMLETLRVTELRLLLSKMGKSKSGLKKDLQKRVTDLLHNDCSPELLS----AVRELHDLRQISKSRRSG--------------IEIIS-------MPESLSPG------------------GTPSPKSAGPQMIKLPFYQ------MLETIIPPTPLVPTYGGAMQNSDFLFHLSESQQALIQNSRSSQP-------VQVVLRICYSESIGVEEDQYPPNICVSVNHNNCPVQCTYSSNKLGLEPSRPCRPIDITSDLYLS--FTNRFTVLWG-NFGKSYSVAVYLVRLVSCQQLLDQLRSSSVEQQDVCRLRVSEKLRSDPETEVATTGLQVSLICPLVKLRMSVPCRSRGCAHLQCFDASFYLQMNEKKPRWSCPVCHRYAPFDELRIDSLLRDVLESSG--EDVEEIKYLSDSTWK---------------------------------------------------------------------------AVKHDKSN---------------QNKGSALHPVKHNVNSKPVRDAVVDLTQSSSD-----------------------------DEDFQKEETVSTHIE--------------------------------------DKSVHFRKSGIVKSARHKGRKTQVHTEKHRNGN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7P5-1", "uniprot_id": "A1Z7P5_DROME", "id": "A1Z7P5-1", "name": "", "aln": "MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTN-LELLAP----KVQEVYAQSVQEQNATLQYIDPTRMYSHIQLPPTVQPNPVGLVGSGQGVQVPGGQMNVVGGAPFLHTHSINSQLPIHPDVRLKKLAFYD------VLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTP---------------------------------------SKPAQKVEVISDDIELISDDAKPVKRDLSPAQD-------EQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVAS---------------STSNGSGGGQRAYTPAQQPQQSESPEQQ--------------------------------------ASRQSPEKQTVSEQQLQQQQHEQPATAAVHASLLESLAAAVADQKHFQLLDLAAVAAAAAATASSGQSQNAGP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12216-1", "uniprot_id": "SIZ2_YEAST", "id": "Q12216-1", "name": "E3 SUMO-protein ligase SIZ2", "aln": "------MASVMSNNNNNNNNNNASYMFTNPLSNTGGGLINEIKDAINEMEQLKVLELKQICKSLDLSITGKKAVLQDRIKQFLRKSCDIGHIDPWRPKAIKILIAKVRINSSLPKYSTLWETLKTG------------------------AFKHPVASGQLPVTALQSTALPPYSQQQALAYS---------FTSPFYKPIVQIPDANKKLKQS-AGRGCTKMKFKVSKSNHDLLKS---NKSYKLYLFSGFSIPFIYETVGHEAIDFPYPCELVFNGTKLEDNVKGLKKQNGTGNPANLTPYLKVPT-EMNHLDLHYL-NIDKEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNEQDDDDIITTSTVLSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQNCN--EDVEQVEISVDGSWKPIHN--------------------------------------------------SSAVITDTVNQNHSVKNENQGTVKQEQDYDSRNAFDTNLRNGSNHNEPEIISLDSSDDEAFIPASKS-FPTHVNPR----------NDQLRADIFPSESEGSSDYNPNHTSTPKGSPTMDQDNY----------------------QDAFQMRSFLNQGATTNINDTPTNNSS--INSFVTATNGDSRIFYNRGPSTPLLPAVLQNLTNQTEAQ--------RNPYGPNYNTTAQDRNLLG---------------------------------------------------IEGDLPPIPPVDPNSEAETELPTRTTSAAHLPPYIHVSTSG--------HGDDGKIRKRRHSNVSIYIPKNPYATLMKRRPQANHAIMNKTLAQTNDFN---TSAQDNSEVVDLTSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04195-1", "uniprot_id": "SIZ1_YEAST", "id": "Q04195-1", "name": "E3 SUMO-protein ligase SIZ1", "aln": "----------MINLEDYWEDETP-----GPDREPTNELRNEVEETITLMELLKVSELKDICRSVSFPVSGRKAVLQDLIRNFLQNALVVGKSDPYRVQAVKFLIERIRKNEPLPVYKDLWNALRKGTPLSAITVRSMEGPPTVQQQSPSVIRQSPTQRRKTSTTSSTSRAPPPTNPDASSSSSSFAVPTIHFKESPFYKIQRLIPELVMNVEVT-GGRGMCSAKFKLSKADYNLLSNP--NSKHRLYLFSGMINPLGSR--GNEPIQFPFPNELRCNNVQIKDNIRGFKSKPGTAKPADLTPHLKPYT-QQNNVELIYA-FTTKEYKLFGYIVEMITPEQLLEKVLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQCPISYTRMKYPSKSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDILQNCQ--KNVEQVELTSDGKWTAILEDDDDSDSDSNDGSRSPEKGTSVSDHHCSSSHPSEPIIINLDSDDDEPNGNNPHVTNNHDDSNRHSNDNNNNSIKNNDSHNKNNNNNNNNNNNNNDNNNSIENNDSNSNNKHDHGSRSNTPSHNHTKNLMNDNDDDDDDRLMAEITSNHLKSTNTDILTEKGSSAPSRTLDPKSYNIVASETTTPVTNRVIPEYLGNSSSYIGKQLPNILGKTPLNVTAVDNSSHLISPDVSVSSPTPRNTASNASSSALSTPPLIRMSSLDPRGSTVPDKTIRPPINSNSYTASISDSFVQPQESSVFPPREQNMDMSFPSTVNSRFNDPRLNTTRFPDSTLRGATILSNNGLDQRNNSLPTTEAITRNDVGRQNSTPVLPTLPQNVPIRTNSNKSGLPLINNENSVPNPPNTATIPLQKSRLIVNPFIPRRPYSNVLPQKRQLSNTSSTSPIMGTWKTQDYGKKYNSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ::* :*: : :. . :* * * ::: :. . . . : :. :: : . . :: * . . . . . : . . .* ::* : * . : : : * : ::*. .: *: :: : :. .* : : : ** :** **: :: *.: * *:***** :*: : : * * **:*. : * *. . .:: . .. ::: :..* .:: : . . . : . : .. : ", "identical_positions": 36, "similar_positions": 103, "identity": "3.88%" }, { "cls_id": "homologset.agr.MGI:2136957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQ75-1", "uniprot_id": "A0A8I5ZQ75_RAT", "id": "A0A8I5ZQ75-1", "name": "Calmin", "aln": "MAAQEWD-WFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLSRSSPSSS-LSPGSGGTDSDSSYPPTPTTERSVAVAVKDQRKAIKTLLSWVQRKTRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFRIAHDSLHIPRLLEPEDIMVDMPDEQSIVTYVAQFLERFPELDPEDFVNPDKEAPIESTFVRIKESPSEQESRVLLLSQNGEQP-------YTVSHETSHPPPDKVFVCDQLESPTGFSLGSAPSHKLPDSPTDFMHQIIDQVFQASMGNTESTTEPTPESSILSTRKDGRRSNSLPVKKSVHFETDLHKDASCSKDPFYSSEFRFEGSPKATKELSKQDG----------HASLAEVSKEKK-PEQEARLVLEAASDKAPEDTIVDTDAMSQ--------------DAQLPQDSSFCNGNVENPASLGEKGPSPPSPRDNTILANSVELKVPLLTVEPMDKD--DYFECIPLKASKFNRDLVDFASTSQAFVEDPSSHKKTPGE-EEGSENYTEKPGKRKSKSPHAETEST---ESRLEPIKLETPPKDPEQEDQGHTLPPETAADKKPEVYEKAKRKSTRHHSEEEGEAEGGLSAVGG-EMPSNPPSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVLEAYAEGGEDLKSEDADLEHPDGSYLQDSREEEEEEDEEEEEAHSSHSSCNFSLPVDNSYPRVNDHVSHVDGSSEGPTSASEPGSPPSHEDHQPMETKENGPVESQQSQEPPTPELSTKPLEEKLTEVPTSSKKKEKRKHMDHVESSLFIAPGTVRSSDDLEENPCEHKVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQLRNAADVDDRRNRLLNRYNSQKLTELILQFYGIRADMKREYKHTRLSMKVFVTGGELSCLVDSSRVTVDWHQLLWRSRAPGEPEPAQRLSDAVCTAARRDIFHSLPLAPGLLLTTLPPARCQPALKHSSGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5W0-1", "uniprot_id": "CLMN_MOUSE", "id": "Q8C5W0-1", "name": "Calmin", "aln": "MAAQEWD-WFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLSRSSPSSS-LSPGSGGTDSDSSYPPTPTTERSVAVAVKDQRKAIKTLLSWVQRKTRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRDNLEKAFSIAHDSLHIPRLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEDFVNPDKEAPIESTFVRIKESPSEQGSRVLLLSENGERA-------YTVNQETSYPPPDKVFVCDQLESPTGFCLDSAPSHKLSDSSTEFMHEIIDQVLQGSTGKTGSIAEPTPESSILSTRKDGRRSNSLPVKKTVHFEADLHKDASCSKDPFYSSDFRFEGSPKATKELSKQDG----------HVSLAEVSKEKKKSEQEARLVLEAASDKVPESTVDGLDAVPQ--------------DAQPSQDSSFCNGTVESPSSQGEKGPPPSSPGDHTLLANSTELKVQLLTVEPMDKE--DYFECIPLKASKFNRDLVDFASTSQAFGEDPSSHEKTRGE-EEGSENHAEKPGKRKSKSPRAETEAA---ESRLEPKKLEPPPKDPEQEDQGHALPPETPADKKPKVYEKAKRKSTRHHSEEEGEAESGFSAVCEEEIPSAPPSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVLEAYAEGGEDLKSEDTDLEHPEDSYLQDSREEE--ADEDEEEAQSSQSSCSFSLPVDNSYPSVSEHVSHVDGSSEGPTSALGPGSPPSHEDHQPKETKENGPVESQQSQEPPNPELPTKPLEEKLTEASTSSKKKEKRKHMDHVESSLFIAPGTVRSSDDLEENSSEHKVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQLRNAADLDDRRNRVLNRYNSQKLTELILQFYGIRADMKREYKHARLSMTGTNSSGEAVPLGNQSPPNDSLTQFVQ------QPD-----------VIYFILFLWLLVYCLLLFPQLDVSRL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JQ2-1", "uniprot_id": "CLMN_HUMAN", "id": "Q96JQ2-1", "name": "Calmin", "aln": "MAAHEWD-WFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLSRNSPSSS-LSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPSEQESKVFVLTENGERT-------YTVNHETSHPPPSKVFVCDKPESMKEFRLDGVSSHALSDSSTEFMHQIIDQVLQGGPGKTSDISEPSPESSILSSRKENGRSNSLPIKKTVHFEADTYKDPFCSKN----LSLCFEGSPRVAKESLRQDG----------HVLAVEVAEEKE-QKQESSKIPESSSDKVAG-DIFLVEGTNN--------------NSQ----SSSCNGALESTARHDEESHSLSPPGENTVMADSFQIKVNLMTVEALEEG--DYFEAIPLKASKFNSDLIDFASTSQAFNKVPSPHETKPDEDAEAFENHAEKLGKRSIKSAHKKKDSP---EPQVKMDKHEPHQDSGEEAEGCPSAPEETPVDKKPEVHEKAKRKSTRPHYEEEGEDDD-LQGVGE-ELSSSPPSSCVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVLEAYVEDPEDLKNEEMDLEEPEG-YMPD-------LDSREEEADGSQSSSSSSVPGE-SLPSASDQVLYLSRGGVGTTPASEPAPLAPHEDHQQRETKENDPMDSHQSQESPNLENIANPLEENVTKESISSKKKEKRKHVDHVESSLFVAPGSVQSSDDLEEDSSDYSIPSRTSHSDSSIYLRRHTHRSSESDHFSYVQLRNAADLDDRRNRILTRKAN--------------------------------SSGEAMSLGSHSPQSDSLTQLVQ------QPD-----------MMYFILFLWLLVYCLLLFPQLDVSRL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RE43-1", "uniprot_id": "A0A8M1RE43_DANRE", "id": "A0A8M1RE43-1", "name": "Calmin", "aln": "MAGHECDGWFEREELIGQISDIRVQNLQVEREVVQKRTFTRWMNLHLEKCNPRMEVRDLFRDIQDGKMLMALLDELSGSKLLHGFKPSSHRIFRLNNIAKVLAFLEERNVKLVSIDATDIADGNPSIVLGLIWNIILFFQIKELTGNIKSQFPSSSSLSSIPTSSDSDTSHSSTPTDERKPTVAPRGHGKVIKTLLQWVQRRTRKYGVAVQDFGKSWTSGLAFLAVIKSIDPSLVDMRRSFLRTPRENIEEAFRTAHYSLGIPKLLEPEDVMLNPPDEQSIMTYVSQFLEHFPGIEEDDTSDIRERSKARARMDDAPVRNGVQRKRETYMVKRDSVHPPPKIFISSVSEEREQIPSPVLLQTPEDRPWTHEESTMGPSPSPANDQPVYPPLDLNKDTPTTSSPQPSLSDSAVNSPDSWSEVHSETTNSHRVTEEPMSERDTTGTVEVTSDLGSPFSPESTPENQLDRELFIDEGNYSLGSMDSLHAKSIAVSEEDDAYKYILDLKEEQSNNPLPRDESCLEDSKTSPSGYHEGEKPTSEVPSCLESDSGFFQDSKEGIPAQPEIGSPLLSPVDEEIISDPFQDDNESSNTQAIQRDTLERTDGPEKKPVTFEYDSEPECPVLQYERVSISGSEEDIKLCTDLTEEPTEEPSKNDLANGHSETNEDSDFNHGEQAGVLKSEVKDVVFDDQEKTVSDQSQSDVEVHDEDQVCYMCGGPVMKSSGDSCEQGDYCLSHSSSTERDCNSDSRHFTESDAGGNFEDNPREQNNELNGTVSDLKNEPRERK--GIREDRLVIGKSDLENGSDGIRRTEFSHNINGES----QAQVSDNTVPGGDQNNRPLSVVDSRKSVTEALLDPLSDSNITDGEKDSILTQSPLRHFPELSSIESLIEPDTTCEDAEPIIGVRGFPERRPAELRLSLSMTPLQPAPPKRSFTESDTDTEDASEDHSNGYKSKKGRAGSLLLQEQSPFDRHPGEWGAVEPDSPAEHCELIKTDDDLIGAGARENTGALREGTVTDASPLLTTIHLRKIDDSSELKGQNGKTLDGIKVDATIINKSSERKSPESTSEALS----------DLVFILLAAWLFVYCLLVLPQIDSRTLPKLLFNMDE-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:* * **:********************* *********:*******:* :** *** ******:*****: *** :*** :*.*************.* ***: *********::*******:********************:. . **** **. . .:***:*...*** **. ::: :.: *.**:** ****:***********. ** **********:********:::: :.*:*:*:** *: :* **:******:*:: ******:***:****:** :: :* : :. .: : . * .: : :... :*..* . *. :: : .. . .* .:. . : ::: . . ::.: :*. :. .. :** :.: * * :.: . . : :* ::* *. *::*.. : * :.: . :. . : *. :. *. . * . . .* :. ::::. : . ..:.::. : : *. .*: * ... * * : : *: :*: .*.. . : :.: : : :. .. : : . :: * : . ::. . :..*: . . .: ... * . *.: .:: :* .::. ** *: . . : . . .**:. . .:...: : : . .::: . .. . .:. * ..: : .. . . . * :. :. ::.. : * . .. : *. . * . : .* ..: :*:* .:. . . : . :.. : **. . : * .: : . ** * . .. : : . : . : * : *::. : ", "identical_positions": 261, "similar_positions": 311, "identity": "23.3%" }, { "cls_id": "homologset.agr.MGI:2136959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59017-1", "uniprot_id": "B2L13_MOUSE", "id": "P59017-1", "name": "Bcl-2-like protein 13", "aln": "MASS---TTASLGFHYETKYVVLSYLGLLSQEKQQGP---SPPGVQLDVAPQSLNPEVLLKLKSEIEEELKTLDKEVSEAFTSTGFDCHTSPVFSPANPESSIEDCLAHLGERVSQDLKEPLQKALQTILSQPVTYEAYRECTVETAVHASGWNKLLVPLVLLQHLLLELTRRGQEPLRMLLQFGVMYLEEHAAEFIIQQGGWGSVFSLEPEEEEYPGIIAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSSGAGEKSENNSSNSDIVHVEKEEVPE------------------EAFPGAAAPLLTQVPTVEAP-------EMMRAEKTSPTPSVFVELGEEELEAVTARPEAVERAE-----GAAQLSEERAGSRKKSHTGEAAAVRGAKSGLPAEG------------------KAVLLFGGAAAVAILAVAVGVALALRRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT71-1", "uniprot_id": "D3ZT71_RAT", "id": "D3ZT71-1", "name": "", "aln": "MASSSSSTTVPLGFHYETKYVVLSYLGLLSQEKQQGP---SPQGSQLDVAPQSLNPEVLLKIKSEIEEELKSLDKEVSEAFTSTGFDCHTSPVFSPANPESSVEDCLAQLGERVSRDLSEPLQKALQMILSQPVTYEAYRECTVETAVHASGWNKILVPLVLLQQMLLELARRGQEPLSTLLQFGVMYLEEHGAEFIIQQGGWGTVFSLESEEEEFPGIIAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSSGAGEKSENNSSNSDIVHVEKEEVPE------------------EAFPGATGPLLPQVTPMEAS-------EMMRVEKTSPTPSVFVELGEEDLEVVTVRPDAVE--------GAAQLSEERSGRRRKSHTGEAIAARGTKSGLPAEG------------------KAVLLFGGAAAVALLAVAVGVALALRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXK5-1", "uniprot_id": "B2L13_HUMAN", "id": "Q9BXK5-1", "name": "Bcl-2-like protein 13", "aln": "MASS---STVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** :*..********************** * ** * ***:*.***: *:***:*:*******:****:********** **************:*****:***:**::*.***:**** :*******:*:****:**:********:*******:::****:******* ****** ***::.**:********:*****.****:*** **************************************************************************.************************* **:* *..***.::.. . *:: .**:**:.*:****.**:::..*..* ** : ***:. . *.:* . * .. *. *:** *::**********:****:*******:*", "identical_positions": 322, "similar_positions": 76, "identity": "65.98%" }, { "cls_id": "homologset.agr.MGI:2136971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYP0-1", "uniprot_id": "ALLC_RAT", "id": "Q6AYP0-1", "name": "Probable inactive allantoicase", "aln": "---MADTPKEGKLTRFLDFTQLIDLASECVGGKVLFATDDFFGPAENLIKSNNPSFKENEYTEFGKWVDGWETRRKRIPGHDWCVIQLGIQG-IIRGIDVDISYFSGNYAPRMSIQAANLS-EDTVTNIPPRGVKMGAAATSEEFVAITELKSHSWDYLVPMSELKPGDPDSSHNYFFVNSQQRWTHIRLNIFPDGGVARLRVYGTGQRDWAALDSTEPVDLVAIAFGGVCVGFSNAHFGHPNNMIGVGDPKSIADGWETARRLDRPPVLEGNENGFLQVPGCEWAVFRLAHPG-VITQIEIDTKYFKGNSPDSCKVDGCILTTLEEEDMIRQKWSLP-AHKWKPLLPVTKLTPNQNHLLDSLTLELQDVITHARITIAPDGGVSRLRLKGFPSSICLLRPLREKPMLRFSLKAGFRANL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHX6-1", "uniprot_id": "ALLC_MOUSE", "id": "Q9JHX6-1", "name": "Probable inactive allantoicase", "aln": "---MTDTPKEGKLTRFLDFTQLIDLASECVGGKVLFATDDFFGPAENLIKSDSPTFKEHEYTEFGKWVDGWETRRKRIPGHDWCVIQLGIQG-IIRGIDVDISYFSGNHAPRMSIQAANLSEEDTMSNIPPRGVRMGTAATPEEFEAVTELKSHSWDYLVPMSELKLGDPDSSHNYYFVNSQQRWTHIRLNIFPDGGVARLRVYGTGQRDWAALDSTEPVDLVAIAFGGVCVGFSNAHFGHPNNMIGVGEPKSIADGWETARRLDRPPVLEASENGLLLVPGCEWAVFRLAHPG-VITQIEIDTKYFKGNCPNSCKVDGCILTTLEEEDMIRHNWNLP-AHKWKSLLPVTKLIPNQNHLLDSLTLELQDVITHAMITIAPDGGVSRLRLKGFPSSICLLRPLREKPLLRFSLKTGFRANL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6M5-1", "uniprot_id": "ALLC_HUMAN", "id": "Q8N6M5-1", "name": "Probable inactive allantoicase", "aln": "----------------------MDMASESVGGKILFATDDFFAPAENLIKSDSPCFKEHEYTEFGKWMDGWETRRKRIPGHDWCVLRLGIQG-VIRGFDVDVSYFTGDYAPRVSIQAANLE-EDKLPEIPERGTRTGAAATPEEFEAIAELKSDDWSYLVPMTELKPGNPASGHNYFLVNSQQRWTHIRLNIFPDGGIARLRVFGTGQKDWTATDPKEPADLVAIAFGGVCVGFSNAKFGHPNNIIGVGGAKSMADGWETARRLDRPPILENDENGILLVPGCEWAVFRLAHPG-VITRIEIDTKYFEGNAPDSCKVDGCILTTQEEEAVIRQKWILP-AHKWKPLLPVTKLSPNQSHLFDSLTLELQDVITHARLTIVPDGGVSRLRLRGFPSSICLLRP-REKPMLKFSVS--FKANP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGA6-1", "uniprot_id": "ALLC_DANRE", "id": "Q6DGA6-1", "name": "Allantoicase", "aln": "---MAKRQVQKETRSQPHFLQFNNLACETAGGKVIFATDEWFAPARNLLKRDPPEFIASAFTEFGKWMDGWETRRKRIPGHDWCIVQLGVPG-IIHGFDVDTSFFTGNYAPFASIQATCLD---QMPSIALEGDRTGMAASPSQFEAVAQLNSDSWKEVVPVTKLKAGYSDTCHNYLSVSYPHRVTHIRFNIYPDGGIARLKVYGIGKKDWSSVFGQDLVDLVALVNGGVCVGFSDAHYGHPRNMIGLGMAENMGDGWETARRLDRPRVLKEDENGILQVPGSEWAIFRLGHPG-IISKIELDTNHFKGNFPDSCRIEACSLTEDEENSFIQSQWSSDRSPMWNILLPPQKMKAHHRHVFSGPSLVHCGPVSHVRMVIAPDGGISRLRIWG--------RPVSSHQMISKL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25335-1", "uniprot_id": "ALLC_YEAST", "id": "P25335-1", "name": "Allantoicase", "aln": "MKFFSLADEAEFKSIIISKNKAVDVIGSKLGGQVVSFSDEWFASAENLIQPTAPIRDPTRFVHSGAWYDGWETRRHNEMEYDWVIIKMGVAAAHIIGGEIDTAFFNGNHAPFVSIEALYDE--------GEEGNIVEDDSRWVEIVEKFECGPSQRHLFVRGNGLT---------------KERFTHIKLKMYPDGGIARFRLYGR-VVPPELKTKDHIIDLAYVCNGAVALKYSDQHFGSVDNLLLPGRGHDMSDGWETKRSR--------------QPGHTDWAVIQLGRESSFIEKIIVDTAHFRGNFPQFITVEGCLKESESSENTGEG--------TWVELVGKSKTGPDKEHVY---EIRKSIRVSHVKLTIIPDGGVKRIRVWGY----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . **::: :*::*..*.**:: * :.. * * *******:. :** ::::*: . * * ::* ::*.*::** **:* . .* : :: : . . .* . *. .* ***:::::****:**::::* . **. : *.*.: :*: ::* *:: * ..:.***** * :**:::*.: . .* :* :** :*.** *: ::.* ..: . * *: * ..: *: : ::*. :.* ****:.*:*: * ", "identical_positions": 83, "similar_positions": 107, "identity": "19.76%" }, { "cls_id": "homologset.agr.MGI:2136976", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQB6-1", "uniprot_id": "D3ZQB6_RAT", "id": "D3ZQB6-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "aln": "MVGLPPPRGSARAAADWLLGCARGGGSRVGETRSLRVRATSAMAALARLGVLGPGRCLWKLPVRLSAEFQGYGPRRGYVADRAERS-PTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLQVPVVFVTNAGNILQRDKAQELSALLECKVDPDQVILSHSPMKLFLQYHNKRMLVSGQGPLVENARALGFQNVVTVDDLR----IAFPELDMVDLQRRPKTMRP-RSDFPAIEGVLLLGEPVRWETNLQLITDVLLSNGHPGAGLATAP--YPHLPVLASNMDLLWMAEASMPRFGHGTFLLCLETIYRKITGHELKYEGLMGKPSILTYRYAEEVIRQQAERRG---WAAPIRKLYAIG----------TCKWQMVERRSN-GLMDKRSSGLQQ--PGAVLP-----------------------SWCALVYT-VLRTQAP---------KHLLLEGQSSHSTG----------TETSASVQSS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WM2-1", "uniprot_id": "HDHD5_MOUSE", "id": "Q91WM2-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "aln": "------------------------------------------MAALAGLGVLGAGRHLWKLPVRLSAGLQGCGPRRGYIAGSAERS-PTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLRVPVVFVTNAGNILQHNKAQELSDLLRCKVDPDQVILSHSPMKLFLQYHSKQMLVSGQGPLVENARALGFQNVVTIDELR----LAFPELDMVDLQRRPKTMRL-RSDFPAIEGVLLLGEPVRWETNLQLIMDVLLSNGHPGTGLATAP--YPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYRKITGNELKYEGLMGKPSILTYQYAEDVIRQQAERRG---WAAPIRKLYAIGDNPMSDVYGANLFHQYLQMANR-GEEEQQTGGQQKQRPSATQS-----------------------CASILVCTGIYSSQDPGSQVPPPGRRELPFHGHRDFSFSPGLLEASHIVHDVNEAVQLVFHQEGWA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXW7-1", "uniprot_id": "HDHD5_HUMAN", "id": "Q9BXW7-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "aln": "------------------------------------------MAAWGCVAALGAARGLCWRAARAAAGLQGRPARRCYAVGPAQSP-PTFGFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGCEVDADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELR----MAFPLLDMVDLERRLKTTPLPRNDFPRIEGVLLLGEPVRWETSLQLIMDVLLSNGSPGAGLATPP--YPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEGLMGKPSILTYQYAEDLIRRQAERRG---WAAPIRKLYAVGDNPMSDVYGANLFHQYLQKATHDGAPELGAGGTRQQQPSASQS-----------------------CISILVCTGVYNPRNPQSTEPVLGGGEPPFHGHRDLCFSPGLMEASHVVNDVNEAVQLVFRKEGWALE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IJ50-1", "uniprot_id": "A0A0R4IJ50_DANRE", "id": "A0A0R4IJ50-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "aln": "-----------------------------------------MAQMFSRLNMLGIGWRGVRFSRKVTNAAVSAQTQRRYSTDVDEQNRHLFGLLFDIDGVLVRGRTPIPAAKQCFRNLVDGDGKYKVPVVFVTNAGNALRQTKAEQLSHLLEVEVSPEQVVLSHSPLRVFTQFHDMCVLVSGQGPVVEVAHNVGFKNVVTIDMLR----EAYPLLDVVDHHRRPKDTIPQTKDLPHIDAVILFGEPIRWETNLQLIVDVLLTNGRPGNPVTSLH--YPHIPVLACNMDLLWMAEAKNPRFGHGMFLVCLESIYKKITGCELKYEALIGKPSVVTYNYAELLIREQAEKLG---WTRPVQRLYAIGDNPMADIYGANLYNRYLKAMNRSRTPQVQAQGGVSGQMAADLHCDDAKCSGQVMVGGSFEHCLPEACSSILVCTGVYNRDMPTDPQETLT-EHRIFHGHRDFRFDPSLTQPSFIVNDVRDGVELVFQLEGWPLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36151-1", "uniprot_id": "YK50_YEAST", "id": "P36151-1", "name": "Mitochondrial hydrolase YKR070W", "aln": "--------------------------------------------------MIG---------------------KRFFQTTS-----KKIAFAFDIDGVLFRGKKPIAGASDALKLLNRN----KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSLVNKYSR-ILAVGTPSVRGVAEGYGFQDVVHQTDIVRYNRDIAPFSGLSDEQVMEYSRDIPDLTTKKFDAVLVFNDPHDWAADIQIISDAINSENGMLNTLRNEKSGKPSIPIYFSNQDLLWANPYKLNRFGQGAFRLLVRRLYLELNG-EPLQDYTLGKPTKLTYDFAHHVLIDWEKRLSGKIGQSVKQKLPLLGTKPSTSPFHAVFMVGDNPASDIIGAQNYG-------------------------------------WNSCLVKTGVYNEGDD-----------------------LKECKPTLIVNDVFDAVTKTLEKYA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* : . :.: :******.**: *..* ..: * . ::* :::**.*. .: ::: :* * .*.. *:: **:* : : : :. :*. * .: *. **::** : * .: * . ::.*:::.:* * :.:*:* *.: ::. : . * :*: .* **** . ***:* * : :. :* ::.* * : :***: :** :*. :: :: . ::* :* : . ** * : :. .* ", "identical_positions": 66, "similar_positions": 102, "identity": "13.25%" }, { "cls_id": "homologset.agr.MGI:2136977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MX7-1", "uniprot_id": "T121B_MOUSE", "id": "Q99MX7-1", "name": "Transmembrane protein 121B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHPALGHPRALSSAPASFPPPPAAARLQPLFLRGGSSRGRRGSGDSSTSTSTSRGGCGGRRGGGGGSPSSSTGAEREDDDESISISKPLVPAAAALPGPPAQGGVPVS------ATAPAAASSTSTPTSSCSMTAADFGAGAAAGTVGGPGSRSAVGAGGTGTGGAASCCSCCCCCCGRPTRSGRRGRRRGCSPSPGCRWGYQALSVVLLLAQGGLLDLYLIAVTDLYWCSWIATDLVVVVGWAIFFAKNSRGRRGGPANSMHNHHQLHHHSAPPLHLSAAASAGAGAKARGGRGGSGGSGAGPGTTGAAGEFAFAYLAWLIYSIAFTPKVVLILGTSILDLIELRAPFGTTGFRLTMALSVPLLYSLVRAISEAGAPPGSAGPLLLQPQQHRAAGCFLGTCLDLLDSFTLVELMLDGRVPLPAHLRYLLIAVYFLTLASPVLWLYELN-TATAAPSWGQTSGPGSCSRLLRLLGGCLVDVPLLALRSLLVVSYQQPLSIFMLKNLFFLGCRGLEALEGCWDRGSWVSPSRARSSYGAPPSAPPPPPPPPPQGGSQRGH--LENEGGPHGYVNTLAVASQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R697-1", "uniprot_id": "M0R697_RAT", "id": "M0R697-1", "name": "", "aln": "MVPEGRKMWSTLRPRPPSTSGSALRAVELATSGNLCSCPAGRMRFQLYSGVASVLPPFLPADPASQAFSSSILASSLPRIQSWFPRCQLLLLPAGLAPLLRPRLSSPGGLLGSPALPQPSHPRLRSPSPAAPVRISPPPDPGASFSSWRGGGSGWPGFPSAASSARGWRGESGRAAPGAPPRTMHPALGHPRALSSAPASFPPPPAAARLQPLFLRGGSSRGRRGSGDSSTSTSTSRGGGGGRRGGGGGSPSSSTGAEREDDDESISISKPLVPAAAALPGPPAQGGVPAS------ATAPAAASSTSTPTSSCSMTAADFGAGAAAGTVGGPGSRSAAGAGGTGTGSAASCCSCCCCCCGRPSRSGRRGRRRGCSPSPGCRWGYQALSVVLLLAQGGLLDLYLIAVTDLYWCSWIATDLVVVVGWAIFFAKNSRGRRGGPANSTHNHHQLHHHSAPPLHLSAAASAGAGAKARGGRGGSGGSGTGPGTAGAAGEFAFAYLAWLIYSIAFTPKVVLILGTSILDLIELRAPFGTTGFRLTMALSVPLLYSLVRAISEAGAPPGSAGPLLLQPQQHRAAGCFLGTCLDLLDSFTLVELMLDGRVPLPAHLRYLLIAVYFLTLASPVLWLYELN-TAVAAPSWGQASGPGSCSRLLRLLGGCLVDVPLLALRSLLVVSYQQPLSIFMLKNLFFLGCRGLEALEGCWDRGSWVSPSRARSSYGAPPSAPPPPPPPPPQGGSQRGH--LENEGGPHGYVNTLAVASQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXQ6-1", "uniprot_id": "T121B_HUMAN", "id": "Q9BXQ6-1", "name": "Transmembrane protein 121B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPALGHPRSVSSASGSFPPPPAAARLQPLFLRGGSFRGRRGSGDSSTSTSTSRGGGGGRRGGGGGSPSSSTGAEREDDDESLSVSKPLVPN-AALLGPPAQVGAPAGPAPVAFSSSAATSSSTSTPTSSCSMTAADFGGGAAAGAVGGPGSRSAGGAGGTGTGSGASCCP-CCCCCGCPDRPGRRGRRRGCAPSPRCRWGYQALSVVLLLAQGGLLDLYLIAVTDLYWCSWIATDLVVVVGWAIFFAKNSRGRRGGAASGAHNHHLHHHHAAPPLHLPAPSAATAGAKARGARGGAGGAGGGLGAAAAAGEFAFAYLAWLIYSIAFTPKVVLILGTSILDLIELRAPFGTTGFRLTMALSVPLLYSLVRAISEAGAPPGSAGPLLLQPQRHRAAGCFLGTCLDLLDSFTLVELMLEGRVPLPAHLRYLLIAVYFLTLASPVLWLYELNAAAAAAASWGQASGPGSCSRLLRLLGGCLVDVPLLALRCLLVVSYQQPLSIFMLKNLFFLGCRGLEALEGCWDRGNRASPSRARGGYGAPPSAPPPPPPPP-QGGSQLGHCISENEGGAHGYVNTLAVASQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F625-1", "uniprot_id": "E7F625_DANRE", "id": "E7F625-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTMTAEIIKDISQPDS-PVSSAPENGQLLFIR--SVASRRDTQTTSGSANLEEG-----------------------------------------------------------SSQPLVSSSATAQPQSYTMTSGEFMQSTPT--------------------------------------FAQRSRKN---------LFYKILCFLVLVLQGGMLDFYLIVFTDLYWCSWIATDLVVISGWAIFFMKNARSKR---------------------------ERACGFHQKSSIFGCN-----------LGEFTFAYLAWLIYVIASTPKVVLVLETSILDLIALKVPFGVTGFKITMLLCAPLLYCLINSIIED--PNGAT--------RFHSQGCFVSTCLDILDSFILVEVLLKNEIPN-VYLRYTVISVYFIALGVPVVWLYELT-----------ASEMNCRWVWARFFTGVLLNAPLLVVRCFLVFVYKTPVSVFMFKNIFFLGCKCLELVEQCASLRGVRRFARGRAGN-----------------AAQFSHCVSENDMCPHGYVNTLAVNTQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. .. * . * * ..*. . * **:* * .**.: :* *:. ..* :: . .:**::: ..* :**:.:* .:.: .:*.*:. *: *..::*: ***:**:***..***************: ****** **:*.:* .* : :.. *.. ***:********* ** ******:* ******* *:.***.***::** *..****.*:.:* * * *:: :.:: ***:.****:**** ***::*...:* .:*** :*:***::*. **:*****. :* .. *:: * *::.***.:*.:**. *: *:*:**:**:*****: ** :* * . . :*.*.. .:* .* **: .********* :*.", "identical_positions": 181, "similar_positions": 132, "identity": "23.69%" }, { "cls_id": "homologset.agr.MGI:2136980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UXZ9-1", "uniprot_id": "KDM5A_MOUSE", "id": "Q3UXZ9-1", "name": "Lysine-specific demethylase 5A", "aln": "-----------MASVGPGGYAA-----------------------------------------------------------------------------------------------------------------------------------EFVPPPECPVFEPSWEEFTDPLSFIG--RIRPFAEKTGICKIRPPKDWQPPFACEVKTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGST--LKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKG--TGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPP---KRTRRVKSQSDSGEVNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNR-------SDAFNMQMRQRKG----TLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED--VIVEYGADISSKDFG--SGFPKKDGQRKMLPEE-----EEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQP-----DLLHQLVTIMNPN--VLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALSASFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDSGKTRTKLTVEELKAFVQQLVSLPCVISQTRQVKNLLDDVEEFHER--AQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVR-LTLSDPQQVTLDVMKKLIDSGVGLAP-HHAVEKAMAELQELLTVSERWEEKAKVCLQAR-PRHSMANLENIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGNNYAYLEQLESLSAKGRPIPVRLDALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKEIIEKEKEKDLDLEPLSDLEEGLEESRDTAMVVAVFKEREQKEIEAMHSLRAANLAKMTIVERIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQK----KGSSWQAKDVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDKARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPHQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQ---PRKSPLVPRSLEPPVLELSP-------GAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDR----FLHIMEDDSIEEKPLKMKGKDSSEKKRKRKLEKVEQLFGEGKQKTKELKKIDKPKKKKLKLNVDKSKELNKLAKKLAKEEERKKKKEKAAAAKVELVKESTEKKRERKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVS-AEMAENEDYICINCAKKQGPDSPGQAPPPPFLMSYKLPMEDLKETS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MJZ8-1", "uniprot_id": "A0A096MJZ8_RAT", "id": "A0A096MJZ8-1", "name": "Lysine-specific demethylase 5A", "aln": "-----------MAGVGPGGYAA-----------------------------------------------------------------------------------------------------------------------------------EFVPPPECPVFEPSWEEFTDPLSFIG--RIRPLAEKTGICKIRPPKDWQPPFACEVKTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGST--LKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKG--TGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPP---KRTRRVKSQSDSGEVNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNR-------SDAFNMQMRQRKG----TLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAIREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED--VIVEYGADISSKDFG--SGFPIKDGQRKMLPEE-----EEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQP-----DLLHQLVTIMNPN--VLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALSASFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDSGKTRTKLTVEELKAFVQQLVSLPCVISQTRQVKNLLDDVEEFHER--AQEAMMDETPDSSKLQVLIDMGSSLYVELPELPRLKQELQQARWLDEVR-LTLSDPQQVTLDVMKKLIDSGVGLAP-HHAVEKAMAELQELLTVSERWEEKAKVCLQAR-PRHSMANLENIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAKGRPIPVRLDALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKEIIEKEKEKDLDLEPLSDLEEGLEETRDAAMVVAVFKEREQKEIEAMHSLRAANLAKMTIVDRIEEVKFCICRKTASGFMLQCELCKDWFHNGCVPLPKSGSQK----KGSSWQAKDVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPHQAMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQ---PRKSPLVPRSLEPPVLELSP-------GAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDR----FLHIMEDDSVEEKPLKMKGKDSSEKKRKRKLEKVEQFFGEGKQKTKELKKIDKPKKKKLKLNVDKSKELNKLAKKLAKEEERKKKKEKAAAAKVELAKESTEKKRERKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVS-PEMAENEDYICINCAKKQGPDSPGHAPPPPFIMSYKLPMEDLKETS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29375-1", "uniprot_id": "KDM5A_HUMAN", "id": "P29375-1", "name": "Lysine-specific demethylase 5A", "aln": "-----------MAGVGPGGYAA-----------------------------------------------------------------------------------------------------------------------------------EFVPPPECPVFEPSWEEFTDPLSFIG--RIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGST--LKIPVVERKILDLYALSKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKG--TGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILP---KRTRRVKTQSESGDVSRNTELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNR-------SDAFNMQMRQRKG----TLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED--VIVEYGADISSKDFG--SGFPVKDGRRKILPEE-----EEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQP-----DLLHQLVTIMNPN--VLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLLDDVEEFHER--AQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVR-LTLSDPQQVTLDVMKKLIDSGVGLAP-HHAVEKAMAELQELLTVSERWEEKAKVCLQAR-PRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQK----KGSSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQ---PRKSPLVPRSLEPPVLELSP-------GAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDR----FLHIMEDDSMEEKPLKVKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVS-PEMAENEDYICINCAKKQGPVSPGPAPPPSFIMSYKLPMEDLKETS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMJ7-1", "uniprot_id": "KDM5_DROME", "id": "Q9VMJ7-1", "name": "Lysine-specific demethylase 5", "aln": "MSAKTEADNTTAANSGGGGVGSGTSSGGGASANGTATPARRLRTRNSTGNGTNSGSESVKKSNANDEPSTPVTPAGATGSHTHAPPGISPAVMERPMPSVPMNHASSSVSASKKYHNSCPHPTPTPAPTGHKKSVHTQPHSSNKFDQGKNEEFHFDTPPECPVFRPTTEEFKNPLAYIS--KIRSIAEKCGIAKILPPATWSPPFAVDVDKLRFVPRVQRLNELEAKTRVKLNFLDQIAKFWELQGSS--LKIPMVERKALDLYTLHRIVQEEGGMEQTTKDRKWAKVANRMQYPSSKS--VGATLKAHYERILHPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIAPPNETNTRRSKRFGNSNASCGLSGVTPTTKPSAG-VFVKTETKEEFKRDLLSSFNAVNSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDGCDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVHLVPTEMVEREFWRIVSSIDED--VTVEYGADLHTMDHG--SGFPTKSS-LYLLPGD-----QEYAESSWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAAPELFSSQP-----DLLHQLVTIMNPN--ILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMALEPAKLTFGIATACYIDMAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDERHCQECNTTCFLSAVACECNDKLIVCLRHYTVLCGCAPEKHTLIYRYTLDEMPLMLQKLKVKAHSFERWLSRCRDIVDAHTPTSVTLQELQELCKEAETKKFPSSLLIDRLNAAAVEAEKCVTVIQQLGINKVRTRSDHNQEAAQYKLTMEELELFVQEIDNLCCIIDEGASVRELLVLGKQFVERSESQLQLSLESLEESELETLINEGSSLRIELQQLDLLQKRLKQCKWYKRSQGLRETSSKLTYQDVKNLLHIAAADLDPTDPYVDKEMRKLQQIGADIEAWESQAAKYFRRLTQQHELGEIEQFLKSASDINGQVPSHGLLKDALRKAREWLRAVEQLQQNNHVTYCHTLEAMIERGLNIPIQLEELSRMQGHLNSAHQWKDNTACAFLKKGTFYTLLEVLMPRSDA--------------------INIDSDLKPR--FQDDFLKEKNPAEIVASFKHAEEQELLDMRELRRQNMNKNPMRD-----MFCLCKSEFRNLMFNCQLCRDWFHEDCVPPPSATNQNGIVNGGSGPGTNRPKWLCPSCVRSKRPRLETILPLLVQLQQLPIRLPEDEALRCLAERAMNWQDRARKALSSPDVSAAQEAIMAQQQQKRRSEGGAGVGNISSPRKPRRRGSLTKEASGSTESDADDDDDEDECRLRIVEDNFSNDEDEPRTAPATSTVNSDLLKLLSDSEIENLLDLMMEGDLLEVSLDETQELWRILETMPPTLLQAEAMERVVQYMQRQRQQHTNPLPTSGAEDSNDSLMVQNSPNSNSNSGGATGSASNSGRNKKRRSNDTGGNSAVPRKKQSTPKQTPGKKGSAAAARKSDAKASPAASTTPGADADAENKQANGGNTNSSTGSGGGNSATTTPTPGSTHKKRKRTSTTATNNNNNNNNNSTNNSNSSTN--LNSNTTSGQGAATGGNNATGGQKKHAQRSQQAAQEDDEE--ECRAENCHKPTGREVDWVQCDGGCNEWFHMYCVGLNRSQIKPDDDYICIRCTKTVAIGTQGSGHSMSVASTTTPGKQRAVQSAR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47156-1", "uniprot_id": "JHD2_YEAST", "id": "P47156-1", "name": "Histone demethylase JHD2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MEEIPALYPTEQEFKNPIDYLSNPHIKRLGVRYGMVKVVPPNGFCPPLSIDMENFTFQPRIQNLENLDLKNRCRLFFMKQLNNFKRSVKDP--SKLILREP-----YTIVEYSDSTHASEILKKKVYFYDVFSELIKDNRTL--TDTTQSFRRKLKFRDISQLRGDISLWRTISKKFNVPIGLLKEIFEKYIAS------------------------------------YYIFLHSLNENVHTALHADQYPKSLLSDDE-------------DDFDLGPDSNSG-----SDFEEDDDDACIVCRKTNDPKRTILCDSCDKPFHIYCLSPPLERVPSGDWICNTCIVGNG-----YYGFTQDTHDYSLPEFQEYCK--RQNSRLLPARKLSIDELEEMFWSLVTKNRRSSLTTVKYGADIHNELPGQITGFPTREFIPKNINGDELIDYLKYCDHPMNLTNLPMAHNSLLPLFKRNISGMTIPWIYIGSLFSTFCWHMEDQYTLSANYQHEGDPKVWYSIPESGCTKFNDLLNDMSPDLFIKQP-----DLLHQLVTLISPYDPNFKKSGIPVYKAVQKPNEYIITFPKCYHAGFNTGYNFNEAVNFTIDFWLPYGFGAITDYKLTQKACVFDMFDLMINVLDK-------------------YNKDTLLFNDAFVRQCYSSLIVFYNTELKRIRKIQAIVPRTTLLEVHTDPNDE----------------------------------------DEEYDIFCSQCKTICSIAFVLRKNNYDSIRTYKRHKKNHLS----IRQWNELSTTDSKVSILCTQDYLKSIQNLNNSDGE----EPYIDDELYFTKSLKDIDSLIKQVGVKLDR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03214-1", "uniprot_id": "ECM5_YEAST", "id": "Q03214-1", "name": "Protein ECM5", "aln": "--MSGHDSVTKISHILNEPVNEKVMVQNGFHESSKIADIELEIQERPSIKQWESPRSAVIPTSNHNFSPFLYTQFKSRGAAPFAPETIKSVDLVELPEGVPARVFHEKTG-----------------------------------------LFYQISPHSIPTFILAKKELPDPIKFYELVEDLGSVYGCVKLKIIPDADKFTQLNVDVDRLWFKARKQFFNSNEFQRTKIVDFYAKLYNFHNKIKKSTLTRIPSIDKRTLDLYRLRSCVKLRGGFNAVCEKKLWAQIGRELGYSGRIMSSLSTSLRSAYAKILLDFDIYEEEEQAARNNEKNEDMVESEIFRHSNSRSRD-------------------------------------EEEPLHKKAKIHRDVFRAGSINHEFKRMRDIKHIKG---------------------------------FPTYFNSLTEFKLGYTQSTETTLPGYDFTFWENGMEIYDKSKYETKTSPVYNLRQYYEKSLAVFTAIVAKFGSSYPDLFAKHTTLPQ-----KEFERLYFHLLSEHFIDFEIDTGLGLPCSMRSPG--NNSSNEKFAIKNILDQ------------WNLDNIPLNELSLLQHLDLDMANFTRTTYDIGMLFSCQGWSVSDHFLPSIDFNHLGSTKLVYSIAPKDMEKFEALIARGKSEWDTIQSRPRYSTSDDELKSFIETDFYKSFLDAEQSADYSNTGDNSKNSFPEDKIAGNTLHDGSQSDFIFEPNFILANGIKLYKTTQEQGSYIFKFPKAFTCSIGSG-----------------FYLSQNAKFAPSSWLRFSSEAAKWTSKMGFLPGLDVNQLLINALLNSNNP--------------------------------------------------VLRKKCRDLISNYVVEEAENSKKLGELIGTVDVVYNKLNYISDISLESTGLSKIVVTHGALQRNLSLKEFVVLLEKPENGAHSICGIPIRDQSGNLNVCLHSYFDSASLGIALDGLDKPPTSYLLVHNEDFEKKWDVLMTSTFRNRTVPLNIIQYLISHTDSNTEFNRMLRSNFDDSLLLIEKCKKFIKT---------------FVDVSCSVKDVDFGNGFNLRHLPLKFSDNMADNLESLYESVRKCSIEFSEKPTIIRLYHVSRQFPIDNRDIIDGNN---LDLLKELYQKSLTIPLKVSYWTKLTRKICR-LEWLSVYEHIFIER--------------------------------------------------CDIKNEDPAKYSLPLLYSYFEFGLKYCDSEDIDKLG---------------------------------------------------------EVRKLILKYQDMMQKVRVFLKKDPPSKISLSDLEDVLLDIEEYRLP-------------------IQSSFFSELDYVIREIENAKKMNDVNILYNTDNIDKIDELIRKNDPKFVKFANQFNGSRLDKRPLASDNSGSVKAKQELKVFKLWNQHLDQIMQKNKFIEILPSIFRCLDLKSDKYIPLESCSKRQTKYCFCRRVEEGTAMVECEICKEWYHVDCISNGELVPPDDPNVLFVCS-----------ICTPPCMAVDNIEGVTFELDDLKRILVESLKLSLIP---------------DPPILKNLFDVFAFALNFKNEMEKELFTNGYVNQLSSTHKIKYYLRKLKGSQCGFTNLTDPLRKHCQVKDAEAIKWLTDNGRIIITGIPN----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.: : :*: :*: : . *: * . : ::. : * .* * ::. : : * :: :* . .. :: : * : . : :. : .: .: .: : . . . . . . .. . . :. : . : : : : . : : .* . . * . .*. :: :::. . . * * .. . .. : : ** *:*: . *:* :. :::.:. . :* *: * .*:: * :: * *..* *.:. ::: : .: *. .:* :::.. : .: :**. :* . . . . * * * . . : .: . : : . : : . . * .: . . : .. : : .. .: : . . ", "identical_positions": 40, "similar_positions": 165, "identity": "2.11%" }, { "cls_id": "homologset.agr.MGI:2137022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYF8-1", "uniprot_id": "D3ZYF8_RAT", "id": "D3ZYF8-1", "name": "", "aln": "MAAAWPAGRASPAAGPPALLRTLWLVTVAAGHCGAAASGAVGGEETPKCEDLRVGQYPPEKPK---INDATQEPVNCTN-YTAHVQCFPAPNITCKDLSGNETHFTGSEVGFLKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFVLISMQIVGPSDGSSYIIDYYGTRLTRLSVTNETFRKTQLYP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MB3-1", "uniprot_id": "TM2D1_MOUSE", "id": "Q99MB3-1", "name": "TM2 domain-containing protein 1", "aln": "MAAAWPAGRASPAAGPPGLLRTLWLVTVAAGHCGAAASGAVGGEETPKCEDLRVGQYICKEPK---INDATQEPVNCTN-YTAHVQCFPAPKITCKDLSGNETHFTGSEVGFLKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYIIDYYGTRLTRLSITNETFRKTQLYP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BX74-1", "uniprot_id": "TM2D1_HUMAN", "id": "Q9BX74-1", "name": "TM2 domain-containing protein 1", "aln": "MAAAWPSGPSAPEAVTARLVGVLWFVSVTTGPWGAVAT-SAGGEESLKCEDLKVGQYICKDPK---INDATQEPVNCTN-YTAHVSCFPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYIIDYYGTRLTRLSITNETFRKTQLYP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PLH4-1", "uniprot_id": "TM2D1_DANRE", "id": "A5PLH4-1", "name": "TM2 domain-containing protein 1", "aln": "MAFRWRSLMRFRSTTRLLLLFTFCLTVIHS-----------LGNDVDSCDKLHLGQYLCKEPR---IDDATQEPETCKD-RVAWVECLPAPNISCRLSNGTQFKFSGEEVGFNKTIPCRNVSGYSYKVAVALSLFLGWIGADRFYLGYPALGLLKFCTVGFCGIGSLVDFMLISMQIVGPSDGSDYIVDYYGARLTRLSITNETYRRMQPSP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2H1-1", "uniprot_id": "TM2D1_DROME", "id": "Q9W2H1-1", "name": "TM2 domain-containing protein biscotti", "aln": "-------------MFPVLLLLLFFFAKETH------------QINVDCNELQMMGQFMCPDPARGQIDPKTQQLAGCTREGRARVWCIAANEINCTETG---------NATFTREVPCKWTNGYHLDTTLLLSVFLGMFGVDRFYLGYPGIGLLKFCTLGGMFLGQLIDIVLIALQVVGPADGSAYVIPYYGAGIHIVRSDNTTYRLPRDDW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : :. : : :**: .* *: **: *. * * *:.* :*.* . :. * : :.*: ..** ..:: **:*** :*.********.:*******:* :*.*:*::**::*:***:*** *:: ***: : : * *:* : ", "identical_positions": 59, "similar_positions": 51, "identity": "27.83%" }, { "cls_id": "homologset.agr.MGI:2137026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51578-1", "uniprot_id": "P2RX5_RAT", "id": "P51578-1", "name": "P2X purinoceptor 5", "aln": "MGQAAWKGFVLSLFDYKTAKFVVAKSKKVGLLYRVLQLIILLYLLIWVFLIKKSYQDIDTSLQSAVVTKVKGVAYTNTTMLGERLWDVADFVIPSQGENVFFVVTNLIVTPNQRQGICAEREGIPDGECSEDDDCHAGESVVAGHGLKTGRCLRVGNSTRGTCEIFAWCPVETKSMPTDPLLKDAESFTIFIKNFIRFPKFNFSKANVLETDNKHFLKTCHFSSTNL-YCPIFRLGSIVRWAGADFQDIALKGGVIGIYIEWDCDLDKAASKCNPHYYFNRLDN--KHTHSISSGYNFRFARYYRDPNGVEFRDLMKAYGIRFDVIVNGKAGKFSIIPTVINIGSGLALMGAGAFFCDLVLIYLIRKSEFYRDKKFEKVRGQKEDANVEVEAN--------------EMEQERPEDEPLERVR------------QDEQSQELAQSGRKQNSNCQVLLEPARFGLRENAIVNVKQSQILHPVKT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VE2-1", "uniprot_id": "P2RX5_MOUSE", "id": "Q91VE2-1", "name": "P2X purinoceptor 5", "aln": "MGQAAWKGFVLSLFDYKTAKFVVAKSKKVGLLYRVLQLTILLYLLIWVFLIKKSYQDIDTSLQSAVVTKVKGVAYTNTTMLGERLWDVADFVIPSQGENVFFVVTNLIVTPNQRQGICAEREGIPDGECSEDTDCHAGESVVAGHGLKTGRCLRVGNSTRGTCEIFAWCPVETKSMPTDPLLKDAEGFTIFIKNFIRFPKFNFSKANVLETGNKHFLKTCHFSSTNL-YCPIFRLGSIVRWAGADFQDIALKGGVIGIHIEWDCDLDKAASHCNPHYYFNRLDN--KHTQSISSGYNFRFARYYRDPHGVEFRDLMKAYGIRFDVIVNGKAGKFSIIPTVINIGSGLALMGAGAFFCDLVLIYLIRKSEFYRDKKFEKVRGQKEEDNVEVEAN--------------EMEQELPEDKPLERVH------------QDEQALELAQSGRKQNSNCQVLFEPARSGLQENAFVNMKPSQILQTVKT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93086-6", "uniprot_id": "P2RX5_HUMAN", "id": "Q93086-6", "name": "P2X purinoceptor 5", "aln": "MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDN--KLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGKAGKFSIIPTIINVGSGVALMGAGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSS------------------------QE-AEDEASGLGL------------SEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCP-QLLEPHRST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R182-1", "uniprot_id": "B0R182_DANRE", "id": "B0R182-1", "name": "P2X purinoceptor", "aln": "MAQT-WGNFFFSLLDYKTEKFVIAKNKKVGVLFRLFQLTVIGYLIGWVFIWKKGYQETEEAIQSSVITKLKGVDLTNSSQFGLQLWGAEDYVIPPQGDRVFFVVTNYLVTPNQRLGYCPESPKVPDGFCTNDNECVEGESVLAGHGVKTGRCLN----DTGTCEINAWCPVEHGHAPVEPMLAKAENFTVYVKNFIKFPKFGFFKSNVLPITNSTYLKTCRYDKDHHPYCPIFLVGDVINWTGYTFQDLATRGGSIGIGIEWNCDLDKDESHCNPEYSFTRLDSSENSQHSVTSGYNFRFARYYNDAAGQTYRNLFKVYGIRFDILVNGKAGRFSIIPTVINIGSGLALMGAGVFACDMILLYMMSKSSFYRETKFEAIKKKQSERESREQRERKHARHHRHHHHHRQDGRHRREEKPTAEMQPLTSILTQANNNPETQTQPSAASALKPHSPERKPQATVSFRTHTTEKHTVSPVSTLRAARHQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*: .: :**:**** *:*:**.****:*:*::* :: **: ***: **.**: : ::**:*:**:*** **:: :* ::*.. *:***.**:.******* :****** . *.* :*** *::* :* **:* **:*:******. ***** ****:* * :*:* .**.**:::**.*:****.* *:**: : :**:*::. : ***** :*.::.*:* ***:* .** *** ***:***** *.*:*.* *.***. : :*::***********.*. * :* *:*.******::******:******:**:***:******.* **::*:*:: * .***:.*:* :: :.. :. *::. : : . . :. : . . .: . *.. : ", "identical_positions": 202, "similar_positions": 131, "identity": "41.65%" }, { "cls_id": "homologset.agr.MGI:2137092", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57772-1", "uniprot_id": "SELB_HUMAN", "id": "P57772-1", "name": "Selenocysteine-specific elongation factor", "aln": "MAG--RRVNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFSVPLPARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRG-APIIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTD-NDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPESKKILTPALKKRARAG-RGEATRQEESAERSEPSQHVVLSLTFKRYVFDTHKRMVQSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHW4-1", "uniprot_id": "SELB_MOUSE", "id": "Q9JHW4-1", "name": "Selenocysteine-specific elongation factor", "aln": "MAG--RRVNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFVVPLPG--------------AEPGSSDTLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLAEGKRQAAIDKMTKKMQKTLENTKFRG-APIIPVAAKPGGPEAPETEAPQGISELIELLKSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGTISLGDSVEIPALKVVKKVKSMQMFHTPVTSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRTLFFSPAPDSFDLEPVLDSFDLSREYLFQEQYLCKDSMPTATEGDDEADPKAGHAPGGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGVLLQGLEDKNYIESFLPALRVYKLKHKHGLVERVMDDYSVIGRSLFKKETNIQLFVGLKVQLSTGEQGIIDSAFGQSGKFKIHIPGGLSPESKKILTPTLKKRSRAG-RGETTKPEEGTERPEPIQPVTLNLSFKRYVFDTQKRMVQTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N878-1", "uniprot_id": "A0A8M1N878_DANRE", "id": "A0A8M1N878-1", "name": "Selenocysteine-specific elongation factor", "aln": "MTDFPKTLNFNVGVLGHVDSGKTSLARALSSTASTAAFDKNPQSKERGITLDLGFSAFTVPLPEHLR----------ESCGEKQYDSLQFTLVDCPGHASLIRTIIGGAQIIDLMMLVVDVVKGMQTQTAECLLIGQLTCSRMVVILNKTDLLPSDKRQVAIDKMTKRMHKTLENTRFKD-CPIIAVAAKPGGPEAPDTDEPQGITELIDLLKAQSFLPHRDPSGSLLMAVDHCFSIRGQGTVITGTILQGSLSVNDNVEIPALKVTRKVKSVQMFRKPVASAMQGDRVGVCVTQFDPKLLERGVVCTPGSLQTLYAAIISVQKIEYYRGALNSRAKFHITVGHETVMARISFFNRVLPANENG---DSKPTSQE-------QSANSFSFDWEFHHLDEHLTSQAEGGKGEPQQWALLEFERPVTCPPLCLVIGSRLDSDIHGNTCRLAFHGKLLEGFEDKNYTETALPRLKISKDKQKEGAVERVTDDYTVIGRNLFKKETNLQLFVGLKVTLSTGEAGSIEGGFGQSGKIKIRIPEGLKEETKQLLSSSSKKKGKGGSKNESPKLEEAKPDAQP---VTIHLNFKRYIYDPHKKMVQS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2H0-1", "uniprot_id": "Q9W2H0_DROME", "id": "Q9W2H0-1", "name": "", "aln": "-----MPINFNIGLLGHVDSGKTTLAKALSSISSTAAFDKNPQSVERGITLDLGFSGLLVDAPAHLP----------------QGEQLQFTFVDCPGHASLIRTIIGGAQIIDLMLLVVDAQKGKQTQTAECLIIGELLQKKLIVVINKIDVYPENQRASKLEKLRLRLAKTLEATTFGGQVPICAVSALQG----------THIAELREVLREAYFQPQRNLADPLFMYVDHCFGIKGQGTVCTGTLLQGKVQVNNVIELPALGEQRKVKSIQMFRKNVTSASMGDRIGLCVTQFNAKLLERGIITQPGYLKPIYAVCLQFKPIRYYKEVIKSMRKMHISVGHNTVMANVTLFRDTDG------------------------TTSTFQLDKEYEYMEDVQPAEVQHN---DVIYALLQFESPVLSPPHSTLIASKLDMDVHSTSCRLAFWGRIAWQTHSSKYFQEELPKLRIFKRKQKVGSIQRVVNSSEVIVQNLFK-DAKRDLYVGKNVELSTGEKGRIERTFGQTSKVAITFQDALSPET----ISNVKN-------------------------VKVLLNCKKYVFNKQAGLFQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.*:*:***:*****:**:***: :*******:*** *********** : * * **.*:***********************:**:*. ** ***:****:**:: .:::*::** *: ...:* ::*: :: **** * * . ** .*:* * *.** ::* * *: :..::* *****.*:***** ***:*.*.:.:.: :*:*** :****:***: ::** ***:*:*****:.******:: * *:.::*. :..: * *:: ::: *:**:***:***.. :* . . : . : .... . :**::** ** .* . :*.*:** *:* .:***** * : .. :* : ** *:: * *:* * ::*. :. ** :.*** ::: :*:** :* ***** * *: ***:.*. * : .*. *: . *: * : *. *:*::: : :.* ", "identical_positions": 219, "similar_positions": 152, "identity": "36.44%" }, { "cls_id": "homologset.agr.MGI:2137202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFE9-1", "uniprot_id": "D3ZFE9_RAT", "id": "D3ZFE9-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAAARYLGRVMLPWNTCVRRGTPSLTYCALFLFLDTFLIHHQRHSLCKMAHQAAFYPCSLNSLLPNRHFAAAAAKS---ARKNKKGAKEKTS-DEKPVDDIEKIKSYTYMESEPEDDVYLKRLYPRRIYEVEKAIHLLKKFQVLDFT-NPKQGVYLDLTLDMALGKK-KKVEPFASVIALPHPFSS-EVNKVAVFTGNASEIKIAEENG-AAFAGGADLVKKILDDEVVV---DFYVAVPEIMGELNPLRKKLKKR---FPKATRNSIGRDIPKMLELFKTAHEIMVDEER----QNFLSTKIATLDMPSDQLAANLQ---AVINEVCRHRPLNLGPFVVRAFLRSS-TSEGLLLKTDSLLPKEAGNAEAA----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N96-1", "uniprot_id": "RM01_MOUSE", "id": "Q99N96-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAAVR-----------CLRR----------------VLIHHQRHCLCKMASQASLYPCSVNSLLHNRHFAAAAAAATKPARKIKKGAKEKTS-DEKPVDDIEKIKSYTYMESDPEDDVYLKRLYPRRIYEVEKAIHLLKKFQVLDFT-NPKQGVYLDLTLDMALGKK-KTVEPFASVIALPHLFSS-EVNKVAVFTANASEIKIAEENG-AAFAGGTDLVKKIMDDEVVV---DFYVAVPEIMGELNPLRKKLKKR---FPKATRNSIGRDIPKMLELFKTAHEIMVDEER----QNFLSTKIATLDMPSDQIAANLQ---AVINEVCKHRPLNLGPFVVRAFLRSS-TSEGLLLKTDSLLPKEAKTTEAETEETQTAEAA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYD6-1", "uniprot_id": "RM01_HUMAN", "id": "Q9BYD6-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAAVR-----------CMGR----------------ALIHHQRHSLSKMVYQTSLCSCSVNIRVPNRHFAAATKSA----KKTKKGAKEKTP-DEK-KDEIEKIKAYPYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFT-SPKQSVYLDLTLDMALGKK-KNVEPFTSVLSLPYPFAS-EINKVAVFTENASEVKIAEENG-AAFAGGTSLIQKIWDDEIVA---DFYVAVPEIMPELNRLRKKLNKK---YPKLSRNSIGRDIPKMLELFKNGHEIKVDEER----ENFLQTKIATLDMSSDQIAANLQ---AVINEVCRHRPLNLGPFVVRAFLRSS-TSEGLLLKIDPLLPKEVKNEESEKEDA------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYL4-1", "uniprot_id": "A0A8M1NYL4_DANRE", "id": "A0A8M1NYL4-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAPAR-----------SVLR----------------VLPRCQSLLFTNRAPSVSCNSLTAHRQQSARSYAATKKKE-----KKEEAVKEKVVKERKIIDDKDRHKPFGLTAWAPVDDVYMVRYYPRPLYELTVAIDMLKSFQKLDFS-AENQPIYINLRLNMKLEKK-RKLDPFVRTIHLPHPFKS-DINKVVVFTEKPDQARIALENG-AAVAGGVELFEKILADEITA---DFYLAEPDILPKLVPLKNKLRKK---FPKSKRGTVGINIPRMLELFKTGHEYIVED-------IYVNTEVATLDMPKEHILENIH---TILKDVASHKPAEFGPIIDRAIVCSR-SSEGLHLKLEELLPQEEKMA-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHT5-1", "uniprot_id": "Q9VHT5_DROME", "id": "Q9VHT5-1", "name": "Large ribosomal subunit protein uL1m", "aln": "MQSILS--------------SMR-------------------ALALRQSTVEPLRLLHLSAVSEAARKGTREKARKKKVK---VEVKKVGFIPHNQRNKKINVKRADKHVDDSWKQVPKDDCYVGRYYRWPVYSVQEAIQCHRETHHPSMYNVPNAPLNLDIELNMQAEKITRFVDNFQRMAMIPHKFDHGEERKIIVFTKGNNEVLEAREAG-ASLVGGVELIKDITSGELLLSDYQYVIAHPNILAELVALRGLMKRK---FPNPKSETLGTNLAEMIVKFSSGISYSAAKDEYQQNFGLITASVGTLDMDVQKLEENIK---FLLQDINTMRPKREGRFITRVLLKSPPSSEQLKIDPFVYVPEMWDKSTAKVKRDGAKKQTEPAEPQEAVASN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04599-1", "uniprot_id": "RM01_YEAST", "id": "Q04599-1", "name": "Large ribosomal subunit protein uL1m", "aln": "----------------------------------------------------MLSVVAIPKICVTGPARRCFFHTAKKLY-------ADDYKPAAMSSNAPSLTKDQAKKRELKRLVQRKAEAKRPATASPLYMP--VTKALRYLRAAEVG-RPQSQQTINLTTLVVGERG---TAPLSGSVTFPKPLRY---IKIAAFTNDESKLEELREKYPNHLIGGADLVAKIKSGEISVD-FDKAFATPDIVPALQSQVARILGPRGVLPSVKKGTVSDDISSLLQESLGSMPFRQRGNS-------ISIGVGKCYFTDREILQNIISARAAFKTAVDNQKSKKPNILSKTTLSST-HGPGIVIDFA-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . :* . . : : .. : ::: : : : :* : *: .** .: * . **..*. .* .*: : .* *:*: * : *. . ::. ::. :: . : :.. : .: *: :: : . :: :. : * . : :. ", "identical_positions": 18, "similar_positions": 68, "identity": "4.53%" }, { "cls_id": "homologset.agr.MGI:2137204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18665-1", "uniprot_id": "RM03_RAT", "id": "P18665-1", "name": "Large ribosomal subunit protein uL3m", "aln": "--MPGWRLLAQGGAQVLGGGAGGLGAAPGLGSRK-NILFVVRNLHSKSSTWWDEHLSEENVSFVKQLVSDEN--KAQLTSLLNPLKDEPWPLHPWEPGSSRVGLIALKLGMMPLWTK-DGQKHAVTLLQVQDCHVLKYTPKEDHN----------GKTATLTVGGKTGSRLYKANSILEFYRDLGLPPKQTTKIFHVTDN-AVIKQGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKRWGFKGQPASHGQTKTHRRPGAISTG-DIARVWPGTKMPGKMGNQNRTVYGLKVWRVNTKHNIIYVN-GSV-GHRNCLVKIKDSTLPAYKDLGKSLPFPTYFPDGDEEELPEDLYDESVRQPSDPSITFA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N95-1", "uniprot_id": "RM03_MOUSE", "id": "Q99N95-1", "name": "Large ribosomal subunit protein uL3m", "aln": "--MPGWRLLAQAGARVLGCGARGLGADPGLERRK-NILFFVRNLHSKSSTWWDEHLSEENLSFVKQLVSDEN--KTQLTSKLNPLKDEPWPLHPWEPGSFRVGLIALKLGMMPLWTK-DGQKHAVTLLQVQDCHVLKYTPKEDHN----------GKIAALTVGGKTVSRFYKPDSRLEFYRDLGLPPKQIHKIFHVTDN-AVIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKRWGFKGQPASHGQTKTHRRPGAISTG-DIARVWPGTKMPGRMGNQNRTVYGLKVWRVNTKHNIIYVN-GSVPGHKNCLVKIKDSTLPAYKDSCKNLPFPTYFPDGDEEELPEDLFDESVWQPSEPSITFA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09001-1", "uniprot_id": "RM03_HUMAN", "id": "P09001-1", "name": "Large ribosomal subunit protein uL3m", "aln": "--MPGWRLLTQVGAQVLGRLGDGLGAALGPGNRT-HIWLFVRGLHGKSGTWWDEHLSEENVPFIKQLVSDED--KAQLASKLCPLKDEPWPIHPWEPGSFRVGLIALKLGMMPLWTK-DGQKHVVTLLQVQDCHVLKYTSKENCN----------GKMATLSVGGKTVSRFRKATSILEFYRELGLPPKQTVKIFNITDN-AAIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKRWGFKGQPATHGQTKTHRRPGAVATG-DIGRVWPGTKMPGKMGNIYRTEYGLKVWRINTKHNIIYVN-GSVPGHKNCLVKVKDSKLPAYKDLGKNLPFPTYFPDGDEEELPEDLYDENVCQPGAPSITFA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IY00-1", "uniprot_id": "A0A0R4IY00_DANRE", "id": "A0A0R4IY00-1", "name": "Large ribosomal subunit protein uL3m", "aln": "MTALTCRFIRLADGLLRGRPVFVFRCGAALQSGA-PVIQCVR--THRSNTWWDEHLTEDNASFLKKLTAEEY--DQMTKDRLNPLKDEPWPRHEWVEGSRRVGLVAIKLGMMPVWSK-SGERHVVTMLQVKDCHVVKHLSKEDYN----------GHTSALVVGGKNVSPFHRPVGYLEIFQNAGIPPKQKLTTFCVTDN-AIIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKRWGFKGQPASHGQTKTHRRPGALGPGGDPAKVFKGTKMPGRMGNVYNTNFGLKIWRVNTKYNILYVN-GSVPGHRNCLVKVRDTVLPTRLEKNKNLPFPTFFADGNEE-LPEDLYDEDMFQFGEPES-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXQ0-1", "uniprot_id": "Q9VXQ0_DROME", "id": "Q9VXQ0-1", "name": "Large ribosomal subunit protein uL3m", "aln": "--MMRSVINQLLGLRLSGNSSVLVTQVRDKGHLSRPRLRNPQWFLRKEITKYNDLMTAENKQFVNEVGTNNFGVPAVIKDSLVKTAGPTANEAVWTPNLRRCGVIARKIGQYPLWLK-NGERIRTTLLQIVDNHVIKYIPPEEYLPAQVPTVANLHKRGCILVGSETTNPALLTKEYAGIFRNSGVLPKKNLARFIVSPE-AQLAPGTPLNVNHFRVGDFVDVRGKTVDHGFQGVVKRHGFKGMPASHGVTKTHRRAGNIGGGGEKGRVWPGTKMPGHMGNRWRIIKGLRVWRINTKYNVMWVQGSSVAGPTGGLVYIYDTILPTRKNK-EAPPFPTFYGEPQQD--GDDVWYEQVHNFKSESITYENE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31334-1", "uniprot_id": "RM09_YEAST", "id": "P31334-1", "name": "Large ribosomal subunit protein uL3m", "aln": "-------MSKFLQGSIFSISKLHVRYS-------------------------------STRPFLVAPSIANS---ITTEAPAINHSPELANARKWLP--KRCGLITRKKGMMPYFDKSTGERSAATILEVNNVEVIMHRTSEVNG------------YFACQVGYGSRHLSKVSRQMLGHFASKVVNPKEHVAEFRVKDEKGLIPPGTLLKPSFFKEGQYVDVRSVSKGKGFTGVMKRYGFKGLRASHGTSIMHRHGGSYGQNQDPGRVLPGRKMPGHMGNEHVTIQNVKVLKVDDENNVIWVK-GSVAGPKNSFVKIQDAIKKT--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . .. *: : * * *::: * * * : * *:: .*:*:: : .*: : . * ** . . : . : **: * :. : . : ** * .*: *::*** . : .:** **:** **** *:** : **: * . . : .:* * ****:*** .::: ::: : *:::*: .** * . :* : *: : ", "identical_positions": 58, "similar_positions": 70, "identity": "15.72%" }, { "cls_id": "homologset.agr.MGI:2137210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCU6-1", "uniprot_id": "RM04_MOUSE", "id": "Q9DCU6-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLRLFQAASRASLRLSGSRVIHSLAEGAERPAEISEPRDSAGLLD-----------PVLRKCELR--IPVHR-RPVQAWVESLRGFEQERIGLAELHPDVFATAPRLDIVHQVAIWQRNFRRISYANTKTRAEVSGGGRKPWQQKGSGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLMQDDLHIVDS------LELPTADPQYLTELAQYRHWGSSVLLVDLTHEEMPKNVVAATSGLNSFNLIPAVGLNVYSMLKHQTLVLTLPSVAFLEDKLLWQDSRYTPLYPFRLPYSDFP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A131-1", "uniprot_id": "D4A131_RAT", "id": "D4A131-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLRLFQAASRAWLRPNGSRVISSLAEDAVRPAEISEPGDSAGLLD-----------PVLRKCELP--IPAPR-RPVQAWVESLRGFEQERIGLAELHPDVFATTPRLDILHQVAVWQRNFKRISYAKTKTRAEVSGGGRKPWQQKGSGRARHGSIRSPIWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLMQDDLHIVDS------LELPTADPQYLTELAQYRHWGSSVLLVDLTHEEMPKNVMAATSRLNSFNLIPAVGLNVYSMLKHQTLVLTLPSVAFLEDKLLWQDSRYTPLYPFRLPYSDFP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYD3-1", "uniprot_id": "RM04_HUMAN", "id": "Q9BYD3-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLQFVRAGARAWLRPTGSQGLSSLAEEAARATENPEQVASEGLPE-----------PVLRKVELP--VPTHR-RPVQAWVESLRGFEQERVGLADLHPDVFATAPRLDILHQVAMWQKNFKRISYAKTKTRAEVRGGGRKPWPQKGTGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLAQDDLHIMDS------LELPTGDPQYLTELAHYRRWGDSVLLVDLTHEEMPQSIVEATSRLKTFNLIPAVGLNVHSMLKHQTLVLTLPTVAFLEDKLLWQDSRYRPLYPFSLPYSDFPRPLPHATQGPAATPYHC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503X2-1", "uniprot_id": "RM04_DANRE", "id": "Q503X2-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MFRATLAICGRTVVKR--QFISSVSGESALPPNLRLPPNLIGVAAEKRPPPSGSDLPVVRRCEAD--VPAHL-TPAQTWLESLGSRDSDQLGVVDLHPDVFSVPIRLDILHAVEVWQRNFKRISYANVKTRAEVRGGGRKPWQQKRTGRARHGSIRSPLWRGGGIIHGPRGPTSYYYMLPMKVRVQGLKIALSAKLAQDYLHIVDS------LEIPTPDPQYLQDLVKHRQWGDSVLIVDVG-EEFPQNILKATEDLKTVNIIPALGLNVHSLLKHESLVLTLEAVKFLEKKLLWHDVRYTPLYPFKLPYSDLP-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3D0-1", "uniprot_id": "Q9V3D0_DROME", "id": "Q9V3D0-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLNNILKTSRQVLYPVARTFSRSGNHGNVVTEAAATVGAPPATRS-----------PLILPQDYTDCLPVSRNTARQAWIENTDAVAERKVGLIELHPDVFAAQPRVDIIQENVEWQSKYRYVSMAHTKTRAEVRGGGRKPWPQKGGGRARHGSLRSPMLKGGGVVHGPRSPTTHFYMLPFYKRVLGLTSTLSVKLAQDDLHIIDN------VDIPTGDAEFLKDLIAERNWGPSVLIVDED-HMFPANICQASDDLGYVNLMPTFGLNVYSMLKHDTLVLTVAAVKHLEQRLLYQLNRNDAASKGGKFKLDQV-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51998-1", "uniprot_id": "RL4P_YEAST", "id": "P51998-1", "name": "Large ribosomal subunit protein uL4m", "aln": "----------MTIKRNLVKTLQSIRYQATTATAHAESTLNP--------------------------LPNAAIPPKYALVTVRSFPSLEPLTFVPVPTSTVAAPLRRDILWRAVVYENDNRRVGASNPPGRSENGFSRRKLMPQKGSGRARVGDANSPTRHNGGRALARTAPNDYTTELPSKVYSMAFNNALSHQYKSGKLFVIGGEKVDLISPTPELDLNRLDLVNTNTVEGKEIFEGEVIFRKFLEEFQLKGKRLLFITDKTREGLIKSSDPYKQKVDVIQKELVEVNDILRAQAVFIELEALEYLAMAHQKEILHSVSN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :* . : : : . : ....:. * **: :: . : :. :: *:* . ** ** **** *. .** :.** . .*. : ** .:. :*: : .. *.::.. * * : * : * .:: : . : .. . * .. . ** * ::.: : : ::. * : . ", "identical_positions": 34, "similar_positions": 72, "identity": "10.27%" }, { "cls_id": "homologset.agr.MGI:2137211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99N94-1", "uniprot_id": "RM09_MOUSE", "id": "Q99N94-1", "name": "Large ribosomal subunit protein bL9m", "aln": "MAASVAPG-VRTLWWAGAAWLRQGGIRELFRPRIEGSTP--GRDFSLSHYQSTVIVERWWKVPLAGEGRKPH-LHRRHRVYKLVEDTKHRPKDNLELILTQSVDEIGVRGDLVSVKKSVGRNKLLSQGLAVYASPENRKLFEEEKSLRREGKLEKIQTKAGEATVKFLRSCHLEVGMKNNVKWELNPEIVARHFFKNLGVVVAPHALRLPEEPITR------WGEYWCDVTVNGLDTVRVPMSVVLFQKPKTKRYKHWLAQQAAKS---VAPTNPQAV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q641X9-1", "uniprot_id": "RM09_RAT", "id": "Q641X9-1", "name": "Large ribosomal subunit protein bL9m", "aln": "MAASMAPR-CSSLLWAGAAWLRQRGIGELLQPRIERSTP--GRDFSLSHYQSTVIVERWWKVPLAGEGRKPR-LHRRHRVYKLVEDTKHRPKDHLELILTQSVDEIGVRGDLVSVKKSVGRNKLLPQGLAVYASPENRKLFEEEKLLRQEGKLEKIQTKAGEATVKFLRSCRLEVGMKNNVKWELNPEIVARHFFKNLGVVVAPHALRLPEDPITR------WGEYWCDVTVNGLDTVRVPMSVVLFRKPKTKRYKHWLAQQAAK------ITSPEAV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYD2-1", "uniprot_id": "RM09_HUMAN", "id": "Q9BYD2-1", "name": "Large ribosomal subunit protein bL9m", "aln": "MAAPVVTAPGRALLRAGAGRLLRGGVQELLRPRHEGNAPDLACNFSLSQNRGTVIVERWWKVPLAGEGRKPR-LHRRHRVYKLVEDTKHRPKENLELILTQSVENVGVRGDLVSVKKSLGRNRLLPQGLAVYASPENKKLFEEEKLLRQEGKLEKIQTKAGEATVKFLKSCRLEVGMKNNVKWELNPEIVARHFFKNLGVVVAPHTLKLPEEPITR------WGEYWCEVTVNGLDTVRVPMSVVNFEKPKTKRYKYWLAQQAAKA---MAPTSPQI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF89-1", "uniprot_id": "RM09_DROME", "id": "Q9VF89-1", "name": "Large ribosomal subunit protein bL9m", "aln": "-------------------MLKNIYVTPLNLLKSATSLQ--------QQVRTTFVLKRKYDPPLHKTNEKPRRMRAKNFIYELVDDTLVKKRPNIEVVLKTFVEGVGDKGDVVSMKPHFVYNKLLLPGLAAYNTPENVAKYAKT---EAEKSTVKHSSPYAQRTVNMLETIVLAVVMNKDEPWVLEPWHIKASLRK-TGFYCREECITLPKERIEGPDLKKENKDFYCTVTINKLEQARLKCRLHHWSTDPSERLPYVLEHWKLQSEPLLDVCSPEKTP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : * : . .: : *.:::* :. ** ..**: :: :: :*:**:** : : ::*::*. *: :* :**:**:* . *:** ***.* :*** : : . * . * .: .: **::*.: * * *::: * *:* : : * *. . : **:: * :::* **:* *: .*: : : . ::* : * : : .*: ", "identical_positions": 57, "similar_positions": 79, "identity": "20.43%" }, { "cls_id": "homologset.agr.MGI:2137215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIE3-1", "uniprot_id": "RM11_RAT", "id": "Q5XIE3-1", "name": "Large ribosomal subunit protein uL11m", "aln": "----MSKLSRVTRTLKKPEAGGVIRSIVRAGQAIPGPPLGPILGQRGVSINQFCKEFNEKTKDIKEGIPLPTKIFIKPDRTFELKIGQPTISYFLKAAAGIEKG------------ARQTG-KEVAGLVSLKHVYEIARVKAKDEAFAMQDVPLSSIVRSIIGSARSLGIRVVKDLSVDELAAFQKERAVFLAAQKRRIWQLRQKLPKSDPNLLHSEVRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQF0-1", "uniprot_id": "RM11_MOUSE", "id": "Q9CQF0-1", "name": "Large ribosomal subunit protein uL11m", "aln": "----MSKLSRATRTLKKPEAGGVIRSIVRAGQAIPGPPLGPILGQRGVSINQFCKEFNEKTKDIKEGIPLPTKIFIKPDRTFELKIGQPTVSYFLKAAAGIEKG------------ARHTG-KEVAGLVSLKHVYEIACVKAKDDAFAMQDVPLSSVVRSIIGSARSLGIRVVKDLSAEELEAFQKERAVFLAAQKEADLAAQAEAAKK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3B7-1", "uniprot_id": "RM11_HUMAN", "id": "Q9Y3B7-1", "name": "Large ribosomal subunit protein uL11m", "aln": "----MSKLGRAARGLRKPEVGGVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKG------------ARQTG-KEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKDLSSEELAAFQKERAIFLAAQKEADLAAQEEAAKK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53875-1", "uniprot_id": "RM19_YEAST", "id": "P53875-1", "name": "Large ribosomal subunit protein uL11m", "aln": "-------MSQAAKNV-------IVKLIVGAGQAAPSPPVGPALGSKGIKAIDFCKEFNARSANYQPGVPVPVLITIKPDRTFTFEMKSPPTGYLLLKALKMDKGHGQPNVGTMLGSAPAKGPTRALGELSLKHVYEIAKIKKSDERHSLLEM--EGIVKSIVGVAKSMGIKVVP----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VFJ2-1", "uniprot_id": "RM11_DROME", "id": "Q9VFJ2-1", "name": "Large ribosomal subunit protein uL11m", "aln": "MSKAAGKLKSLKKTVERVTHTSKLKTNIPAGMAAAGPPLGPMLGQRAINIAAFCKDFNAKTAEMKEGVPLPCRISVNSDRSYDLAIHHPPATFFLKQAAGIQRG------------TMTPG-KEVAGMITLKHLYEIAAIKIQDPPNVLLTM--QQMCEMLISIARTCGIKVVREIDPAAYGEFLEERKLIVEQQRRELQEKREAKMLRTG---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: : ** * ..**:** **.:.:. ***:** :: : : *:*:* * ::.**:: : : *. ::* * :::* : * ... * ::***:**** :* .* : : . : . ::. *:: **:** ", "identical_positions": 40, "similar_positions": 54, "identity": "18.18%" }, { "cls_id": "homologset.agr.MGI:2137218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFW4-1", "uniprot_id": "Q5XFW4_RAT", "id": "Q5XFW4-1", "name": "Large ribosomal subunit protein uL13m", "aln": "----------------MWYLLDGKMQ--PPGKLAAIASNKLQGLHKPVYHQLSDCGDHVVIINTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHL-KDPVAIVKLATYGMLPKNLHRRTMMQRLHLFPDEDIPEDILKNLVEELPQPRRVPKRLDEYTQEEIEAFPRVWAPPDDFRI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1P0-1", "uniprot_id": "RM13_MOUSE", "id": "Q9D1P0-1", "name": "Large ribosomal subunit protein uL13m", "aln": "MSSFSRAPQQWATFARMWYLLDGKMQ--PPGKLAVIASNKLQGLNKPVYHQLSDCGDHVVIINTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHR-KDPVAIVKLAIYGMLPKNLHRRTMMQRLHLFPDEDIPEDILKNLVEELPQPRRVPKRLDEYTQEEIEAFPRVWTPPDDFRM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYD1-1", "uniprot_id": "RM13_HUMAN", "id": "Q9BYD1-1", "name": "Large ribosomal subunit protein uL13m", "aln": "MSSFSRAPQQWATFARIWYLLDGKMQ--PPGKLAAMASIRLQGLHKPVYHALSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHL-RDPVAIVKLAIYGMLPKNLHRRTMMERLHLFPDEYIPEDILKNLVEELPQPRKIPKRLDEYTQEEIDAFPRLWTPPEDYRL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ38-1", "uniprot_id": "RM13_DROME", "id": "Q9VJ38-1", "name": "Large ribosomal subunit protein uL13m", "aln": "-MSIAKRVQQWATFARTWHIYDCTWQ--NPFESAKLVKTHLLGLQKPIYHPMNDCGDHVVLINTREIALPGDEWVKRVYFHHTGYPGGASWTLAWQLHE-KDPTMVMKKAVYNSMRGNLQRRHTMQRLHLFADDQVPEEILQNVTNQIRTPRSIPQRLDHIDKETLENFPNIMDYPKDYILR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12487-1", "uniprot_id": "RM23_YEAST", "id": "Q12487-1", "name": "Large ribosomal subunit protein uL13m", "aln": "--MSQKIGHSGLAFARLWHHVDVARDKRTLGRLASAIAITLIGRHKPVYHPSQDCGDYVVVTNCQKIRVTGKKFEQKTYWSHSGRPGQLKLQTMNKVVADKGFGEILKKAVSGMLPKNKLRKQRLDRLKVFDGS--ENPYKQNITAFAHEQSSIPEPLKESIFNQLK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * : . * * * :**:** .****:**: * :.* ..*.:: ::.* *:* ** :: :. ::* * . : * *: ::**::* .. : :*:. :*: *.. : :. ", "identical_positions": 33, "similar_positions": 45, "identity": "18.13%" }, { "cls_id": "homologset.agr.MGI:2137219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M818-1", "uniprot_id": "RM16_RAT", "id": "Q5M818-1", "name": "Large ribosomal subunit protein uL16m", "aln": "MWRLLTRAPAPLWRMHFSD---TWAALPTSAGLKTLLPVPTFENVSIPERSKLKFVERVPLVPKVRREP---KNLKDIRGPSAEATDFTEGNFAILALGGGY-LHWGHFEMMRLTINRFMDPKNMFAIWRVPAPFKPITRKGVGQRMGGGKGAIDHYVTPVKTGCLIVEMGG-RCEFEEVKRVLNQVAHKLPFPAKAVSRKTLEKMHQNQKERELNNQNPWTFERIATANMFGIRKFLSPYDLTQKGRYWGKFYMPKRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N93-1", "uniprot_id": "RM16_MOUSE", "id": "Q99N93-1", "name": "Large ribosomal subunit protein uL16m", "aln": "MWRLLTRVPAPLLRMHFSD---SWAALPTSAGLKTLLPVPTFENVSIPERSKLKFVERVPLVPKVRREP---KNLKDIRGPSTEATDFTEGNFAILALGGGY-LHWGHFEMMRLTINRFMDPKNMFAIWRVPAPFKPITRKGVGQRMGGGKGAIDHYVTPVKTGCLVVEMGG-RCEFEEVKGILNQVAHKLPFPAKAVSRKTLERMHQNQRERELNNQNPWTFEHIATANMFGIRKFLSPYDLTQKGRYWGKFYMPKRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX20-1", "uniprot_id": "RM16_HUMAN", "id": "Q9NX20-1", "name": "Large ribosomal subunit protein uL16m", "aln": "MWRLLARASAPLLRVPLSD---SWALLPASAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVPKVRREP---KNLSDIRGPSTEATEFTEGNFAILALGGGY-LHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGG-RCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFYMPKRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JM36-1", "uniprot_id": "B8JM36_DANRE", "id": "B8JM36-1", "name": "Large ribosomal subunit protein uL16m", "aln": "MFPVVKSVFLGIVRSSSQRDVLQKQMKLLSAGMRTYEIPPDFSDVELPEKPKLKFMEKVPNLKQAKKEM---KRLRDIQGPSRTATKFSQGQYGILALGGGF-LHWGHIEMMRLTINRSIDPSSMFAVWRFQPPHKPITRKSLGQRMGGGKGAIDHYVTPIKCGRLVLEMGG-QLELVQVEAMLKQVAKKLPFPAKVVSRESLALMYKEHAERVSNNQNPWSFQKIVRSNMLGIRKVLSPLDVHNHGRYTGKFFDPSRV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W547-1", "uniprot_id": "Q9W547_DROME", "id": "Q9W547-1", "name": "Large ribosomal subunit protein uL16m", "aln": "--MLSLKLVSQLFKQSLAS---GNMAIVNTAGLKYFAPPIKYQNVEQPERPKLRVIERQPQLPPNIRPPKMQKRLRYMRGPEMVHNTLLHKQYAIVATGGGR-LRWGHYEMMRLTIGRKMNVNTMFATWRVPAPWQPITKKGQGQRMGGGKGAIDHYVTPIKAGRVIVEIAG-KCEFVEVKQFLQQVANQLPFQATVVSQEMLDEQRVAEEEQTRQNENPFTMKYVIQNNLSGCHRWLSPVDHKWFGKHL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38064-1", "uniprot_id": "RM16_YEAST", "id": "P38064-1", "name": "Large ribosomal subunit protein uL16m", "aln": "MFPYLTRMNLSIKMG--------------GLTLKESSPNAFLNNTTIARRFKHEYAPRFKIVQKKQKGR-----VPVRTGGSIKGSTLQFGKYGLRLKSEGIRISAQQLKEADNAIMRYVRPLNNGHLWRRLCTNVAVCIKGNETRMGKGKGGFDHWMVRVPTGKILFEINGDDLHEKVAREAFRKAGTKLPGVYEFVSLDSLVRVGLHSFKNPKDDPVKNFYDENAKKPSKKYLNILKSQEPQ-YKLFRGR-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: .:. ..: * . : : : : * . . : ::.: . * : : : :* * : . ** . .: *. *** ***.:**::. : * ::.*: * . .. : :.. :** ** * :. :: . . *.. : . ", "identical_positions": 25, "similar_positions": 60, "identity": "9.65%" }, { "cls_id": "homologset.agr.MGI:2137221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BYC9-1", "uniprot_id": "RM20_HUMAN", "id": "Q9BYC9-1", "name": "Large ribosomal subunit protein bL20m", "aln": "MVFLTAQLWLRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYLKKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYEPKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQL4-1", "uniprot_id": "RM20_MOUSE", "id": "Q9CQL4-1", "name": "Large ribosomal subunit protein bL20m", "aln": "MVFLTTRLWLRNRLTDRYWRVQEVLKHAQHFRGRKNRCYRLAVRAVTRAFVKCTKARRLKKRNLRTLWINRITAASQEHGLKYPAFIVNLIKCQVELNRKVLVDLAIYEPKTFKSLAALAKRRQQEGFAAALGDGKEPEGIFSRVVQYH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VU36-1", "uniprot_id": "Q9VU36_DROME", "id": "Q9VU36-1", "name": "Large ribosomal subunit protein bL20m", "aln": "MVFLNLPLLVRSRGPDEFWRKRRIFKLAAHYRSRTRNVYSFAIRSVHRALAYATKGRKLKKLDMAQLWSTRVEAGCQQYGVGLETFKEGLARSDILLNKKVLSDLAIWEPRSFEALVKISRERAAVEGMPDIKRRSAFNQVYGLSNLKLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****. * :*.* .*.::* :.::* * *:*.*... * :*:*:* **:. .**.* *** :: ** .*: *..*::*: :: .* :.:: **:*** ****:**::*::*. :: .* . : . : ::. ", "identical_positions": 47, "similar_positions": 56, "identity": "31.33%" }, { "cls_id": "homologset.agr.MGI:2137224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTW8-1", "uniprot_id": "D3ZTW8_RAT", "id": "D3ZTW8-1", "name": "Large ribosomal subunit protein bL27m", "aln": "---SLNSVSAFSALTALLSPTAPTALAVRSASKKTGGSSKNLGGKSRGKHYGIKKMEGHYVHAGNILGTQRQFRWHPGAHVGLGKNKCLYALEEGIVRYTKEVYVPNP--------------------------------KNSEAVNLVTSLPKGAVLYKTFVHVVPAKPEGTFKLVDML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N92-1", "uniprot_id": "RM27_MOUSE", "id": "Q99N92-1", "name": "Large ribosomal subunit protein bL27m", "aln": "MAAAALTLRTRAAVTALLSPTAPTALAVRHASKKTGGSSKNLGGKSRGKHYGIKKMEGHYVHAGNILGTQRQFRWHPGAHVGLGRNKCLYALEEGIVRYTKDVYVPNP--------------------------------KNTEAVDLVTSLPKGAVLYKTFVHVVPAKPEGTFKLVDML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0M9-1", "uniprot_id": "RM27_HUMAN", "id": "Q9P0M9-1", "name": "Large ribosomal subunit protein bL27m", "aln": "MASVVLALRTRTAVTSLLSPTPATALAVRYASKKSGGSSKNLGGKSSGRRQGIKKMEGHYVHAGNIIATQRHFRWHPGAHVGVGKNKCLYALEEGIVRYTKEVYVPHP--------------------------------RNTEAVDLITRLPKGAVLYKTFVHVVPAKPEGTFKLVAML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86BM8-1", "uniprot_id": "Q86BM8_DROME", "id": "Q86BM8-1", "name": "Large ribosomal subunit protein bL27m", "aln": "--MQKLTMQCLKADQPLMT-------TVRNASKKTGGSTRNKKGHARPKHRGWRVQDGHHVSEGTILATQLTTRFHPGLNVGFGRNGTLFAMEHGKVYVTCEAIDPN---------------------------------WDHTWIQRNYAGRQGQNIYKKFFNVVPENQHQRFRLVEEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12687-1", "uniprot_id": "RM02_YEAST", "id": "P12687-1", "name": "Large ribosomal subunit protein bL27m", "aln": "---MWNPILLDTSSFSFQKHVSGVFLQVRNATKRAAGSRTSMK-DSAGRRLGPKKYEGQDVSTGEIIMRQRGTKFYPGENVGIGKDHSIFALEPGVVRYYLDPFHPKRKFIGVALRRDLKLPSPHFEPTVRRFGRFELTNKRAAYKEENSISRKDYLAKPNILKQLEVRESKRKELQDKLSKVLRDELKLDIKDIELATSYLIRVRASLKNGYPIEDARFNSRYYLKEEERLKARRESWTNEKLSESLSKIDECSDLLNSSTSFNNKLELHQYISEQEKQALKAKLLEDLEKSQHLETKKDKNYIKALFKDACNFLTLSEEVHLRRKYLKSVFPETDSTVETKSGKKSIVSRRFDYTKNKVEVIARSRRAFLSKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : .: . ** *:*::.** . .: :: * : :*: * * *: * :::** :**.*:: ::*:* * * : *: : :. .:.: : . .* : ", "identical_positions": 23, "similar_positions": 42, "identity": "6.13%" }, { "cls_id": "homologset.agr.MGI:2137225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABL7-1", "uniprot_id": "D4ABL7_RAT", "id": "D4ABL7-1", "name": "Large ribosomal subunit protein bL33m", "aln": "MLLSAVSFAKSKSKTILVKLVSQAGTGFSFNYKRSRLREKLTLLHYDPIVNKKVLFVEQKK-----------IRSL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQP0-1", "uniprot_id": "RM33_MOUSE", "id": "Q9CQP0-1", "name": "Large ribosomal subunit protein bL33m", "aln": "MLLSAVSFAKSKSKTILVKLVSQAGTGFSFNHKRSRLREKLSLLHYDPIVNKKVLFVEQKK-----------IRSL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75394-1", "uniprot_id": "RM33_HUMAN", "id": "O75394-1", "name": "Large ribosomal subunit protein bL33m", "aln": "MFLSAVFFAKSKSKNILVRMVSEAGTGFCFNTKRNRLREKLTLLHYDPVVKQRVLFVEKKK-----------IRSL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2L677-1", "uniprot_id": "A0A0G2L677_DANRE", "id": "A0A0G2L677-1", "name": "Large ribosomal subunit protein bL33m", "aln": "MFLTTVNLAKSKSKTLLVQMVSAAGTGYSFNTKRGRLREKLVLRKNDPIVNKHVLFFEKKK-----------VRSL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4L1-1", "uniprot_id": "RM33_DROME", "id": "Q9W4L1-1", "name": "Large ribosomal subunit protein bL33m", "aln": "MRLTNVLFKKVKSKRIMVVLESVV-SGHQFNAFRDRLADKLEIIRFDPYIQQESLYRERKK-----------IRSA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36533-1", "uniprot_id": "RM39_YEAST", "id": "P36533-1", "name": "Large ribosomal subunit protein bL33m", "aln": "-------MVKVKSKNSVIKLLSTAASGYSRYISIKKGAPLVTQVRYDPVVKRHVLFKEAKKRKVAERKPLDFLRTAK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *** :: : * . :*. : : : ** :::. *: * ** :*: ", "identical_positions": 13, "similar_positions": 17, "identity": "16.88%" }, { "cls_id": "homologset.agr.MGI:2137226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEG6-1", "uniprot_id": "D4AEG6_RAT", "id": "D4AEG6-1", "name": "Large ribosomal subunit protein bL32m", "aln": "MRSKSVSFNFFLFALIGGESEVPRGNWKLEFLDHTQPLTCAHAQGTCACSDQEGGEVGGLMHALRPRPALVRNMAPSLLLLSL-PWPVRSGPLHRCWELLQRQLKQTWSGFASPQWAPALAVQSPS--------TLTELAYDTSKNKENSSFLDSIFWMAAPKNRRTIEVNRCRRR----NPHKLIKIKNNIDICPECGHLKQKHVLCGYCYEKVSQETTKIRQQIWAQEGGPFKAPSIETVVLYTGE---KPSEKDQGKRIVERNIKRPSWFTQN---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCI9-1", "uniprot_id": "RM32_MOUSE", "id": "Q9DCI9-1", "name": "Large ribosomal subunit protein bL32m", "aln": "-------------------------------------------------------------------------MAPSLLLLSL-PWPVRPGPLQRCWELLQRQLQQSWSRFVSPPWAPALAVQRPS--------ILTELAHDTCENKENSSFLDSIFWMAAPKNRRTIEVNRCRRR----NPQKLIKIKNNIDICPECGHLKQKHVLCGYCYEKVRQETTKIRQQIGAQEGGPFRAPSVETMVLYTGE---KPSEKDQGKRIVERNIKRPSWFTQN---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYC8-1", "uniprot_id": "RM32_HUMAN", "id": "Q9BYC8-1", "name": "Large ribosomal subunit protein bL32m", "aln": "-------------------------------------------------------------------------MALAMLVLVVSPWSAARGVLRNYWERLLRKLPQSRPGFPSPPWGPALAVQGPA--------MFTEPANDTSGSKENSSLLDSIFWMAAPKNRRTIEVNRCRRR----NPQKLIKVKNNIDVCPECGHLKQKHVLCAYCYEKVCKETAEIRRQIGKQEGGPFKAPTIETVVLYTGE---TPSEQDQGKRIIERDRKRPSWFTQN---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R044-1", "uniprot_id": "F1R044_DANRE", "id": "F1R044-1", "name": "Large ribosomal subunit protein bL32m", "aln": "-----------------------------------------------------------------------------MTLLGL------LQFLGRSLHRLELRLAQA-AGFDS--LGPALAVNGPS--------VFPQHSHNSDEENSQPSFLDSIFWMAAPKKRRTIEVNRCRRR----NPNKMIKVKYNFEPCLECGNMKLKHTLCGFCYEKISKETTNIRRQMSVMEGGPLKAPAVESVVLYESE---KPSDADQGKRIVERNRKRPYWFSL----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9Z1-1", "uniprot_id": "RM32_DROME", "id": "Q9V9Z1-1", "name": "Large ribosomal subunit protein bL32m", "aln": "--------------------------------------------------------------------------------------------MSRNLFLSITNFIRNLESLFLPHGGHPPALALAG--------FQHDHSPKSSQEFSLKQLIGDGLLWAVPKHRRSVEKRLKRKFGYPEYNWKPLREKRNLRSCLQCGHDHEMGVLCPFCYQKVLKETELMQSKIQETLG--LDPVDKEVIVLYEGEKAEQSTDDLKNKRIVEMKKPRPMWFTKNLLQKSTQQLSETKEVKPSDLA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25348-1", "uniprot_id": "RM32_YEAST", "id": "P25348-1", "name": "Large ribosomal subunit protein bL32m", "aln": "----------------------------------------------------------------------------------------MNSLIFGKQLAFHKIVPTTAIGWLVPLGNPSLQIPGQKQLGSIHRWLREKLQQDHKDTEDKDFFSNNGILLAVPKKKVSHQKKRQKLYG---PGKKQLKMIHHLNKCPSCGHYKRANTLCMYCVGQISHIWKTHTAKEEIKPRQEEELSELDQRVLYPGRRDTKYTKDLKDKDNYLERRVRTLKKD-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . . . : .. : *.**:: : : . : * :: :: * .**: : .** :* :: : : : *** .. :. :.* *. ", "identical_positions": 15, "similar_positions": 39, "identity": "5.05%" }, { "cls_id": "homologset.agr.MGI:2137227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FGS0-1", "uniprot_id": "F7FGS0_RAT", "id": "F7FGS0-1", "name": "Large ribosomal subunit protein bL34m", "aln": "KGQQPIPRTAARVVPTTLGRPLPVAEAENYNSQKIRGGQNVIHTAGDYTRSPPPGYFGELHATEDRVSSLSSSAGVELQLPKCPVAIGGTTFPRRHCQGAQSVGTEVDPDDQASDPPLDMAFLARCFGGQACRSVILLSGRYLQSRVWMGLPD-AWS-LSLQQVRGRTRGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N91-1", "uniprot_id": "RM34_MOUSE", "id": "Q99N91-1", "name": "Large ribosomal subunit protein bL34m", "aln": "-----------------------------------------------------------------------------------------------------------------------MAFLARCFGCQACRSVALLSGRYLQSRVWMGLPD-SWPLLSLQQARGRARGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ48-1", "uniprot_id": "RM34_HUMAN", "id": "Q9BQ48-1", "name": "Large ribosomal subunit protein bL34m", "aln": "-----------------------------------------------------------------------------------------------------------------------MAVLAGSLLGPTSRSAALLGGRWLQPRAWLGFPD-AWGLPTPQQARGKARGNEYQPSNIKRKNKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QEZ5-1", "uniprot_id": "E9QEZ5_DANRE", "id": "E9QEZ5-1", "name": "Large ribosomal subunit protein bL34m", "aln": "--------------------------------------MNTLRTA-----------FSRLNG----AHSLCCRNGAPSSIFSCS----------------------------------QLRSLSSVLSRSRPEQNSILQG-TLNPKVEGAFQQPLWN---HQQVRTVKRGTEYQPSNIKRKRTHGWIKRISTPGGIEVILRRMLKGRKSLTH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E959-1", "uniprot_id": "RM34_DROME", "id": "Q0E959-1", "name": "Large ribosomal subunit protein bL34m", "aln": "-------------------------------------------------------------------------------------------------------------------------MLQGMLQR--TCLAVVSTAQTLIVRDKHAFNR--------AVLKPKVRCHFPKPMEVKRINVHGWNARMSTPEGRRVLMNRILKGRHNLSH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04598-1", "uniprot_id": "RM34_YEAST", "id": "Q04598-1", "name": "Large ribosomal subunit protein bL34m", "aln": "-------------------------------------------------------------------MPLFARLCQPQ----------------------------------------SRRMFSSISSFSALSVLRPQTGMLLNSSPLKTPSFTPLGFGLIGQRRWKSRGNTYQPSTLKRKRTFGFLARAKSKQGSKILKRRKLKGRWFLSH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : * :* :** . .*: * .: * .:: .* **** *:*", "identical_positions": 15, "similar_positions": 15, "identity": "7.08%" }, { "cls_id": "homologset.agr.MGI:2137228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ39-1", "uniprot_id": "RM36_RAT", "id": "B2RZ39-1", "name": "Large ribosomal subunit protein bL36m", "aln": "MAALFVRSVVASVVD----LSRLAVKP--------RAFS-ILLGTLP-------SAKPCAEVRSLLCG--GPVLSLQPSLGFKTKGVIKKRCRDCYMVKRRGRWFVLCKTNPKHKQRQM---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N90-1", "uniprot_id": "RM36_MOUSE", "id": "Q99N90-1", "name": "Large ribosomal subunit protein bL36m", "aln": "MAALLVRSVVASVVDPFLHLSRLAVKP--------RVFSSFLLGTLP-------RAKPCAEVRSVLCG--RPLPTLLPSLGFKTKGVIKKRCKDCYKVKRRGRWFILCKTNPKHKQRQM---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0J6-1", "uniprot_id": "RM36_HUMAN", "id": "Q9P0J6-1", "name": "Large ribosomal subunit protein bL36m", "aln": "MANLFIRKMVNPLLY----LSRHTVKP--------RALSTFLFGSIRGAAPV--AVEPGAAVRSLLSP--GLLPHLLPALGFKNKTVLKKRCKDCYLVKRRGRWYVYCKTHPRHKQRQM---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWG3-1", "uniprot_id": "RM36_DANRE", "id": "Q1LWG3-1", "name": "Large ribosomal subunit protein bL36m", "aln": "---MLLRSLVGSLTRQWSQFARCAASLSLPAVGAQRCLSTITAAAVPFRAVVNPMFKPHTAFLSPLLGRCQQLLCVQPSAGMKTKSALKKRCNECFFVRRRGRLFVFCKAHPRHKQRQG---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O14464-1", "uniprot_id": "RTC6_YEAST", "id": "O14464-1", "name": "Large ribosomal subunit protein bL36m", "aln": "---MFLQTLRLTMPR---MFLHMKPSP----------ITITRACTVP-------SLLSVAAPQPALVAANRPLVFNR---GFKVRTSVKKFCSDCYLVRRKGRVYIYCKSNKKHKQRQG---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9I7Q9-1", "uniprot_id": "Q9I7Q9_DROME", "id": "Q9I7Q9-1", "name": "Ribosomal protein", "aln": "--MSLASRILQQGSRLWNGLSAARGFH--------LLTRPAAPAIVSIQSSQLVAATTGICQTSGLLT--PGSTLVQQVAGFKVKGRLKRRCKDCYIVVRQERGYVICPTHPRHKQMSMKKRDYKSWILTHATQSKERGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . * *:* : :*: * :*: * *: * :: * :: :*** . ", "identical_positions": 13, "similar_positions": 19, "identity": "9.29%" }, { "cls_id": "homologset.agr.MGI:2137229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXF8-1", "uniprot_id": "D3ZXF8_RAT", "id": "D3ZXF8-1", "name": "Large ribosomal subunit protein mL43", "aln": "--MTARGTPSRFLTSVLHNGLGRYVQQLQRLSLTLSRDAPSSRGAREFVEREVTDFARRNPGVVIYLNPRPCAVPRIVAEYLNGAVREENVNSKSVEEITSLVQKLADQSG-LDVIRIRKP---FHTDNPSIQGQWHPFTNKRTTFHGLRPRELQDSAPASI-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N983-1", "uniprot_id": "RM43_HUMAN", "id": "Q8N983-1", "name": "Large ribosomal subunit protein mL43", "aln": "--MTARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSG-LDVIRIRKP---FHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDPAPAQDTGLRLSAVAPQILLPGWPDPPDLPTVDPISSSLTSAPAPMLSAVSCLPIVPALTTVCSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99N89-1", "uniprot_id": "RM43_MOUSE", "id": "Q99N89-1", "name": "Large ribosomal subunit protein mL43", "aln": "--MTGRGTSSRFLTSVLHNGLGRYVQQLQRLSLSLSRDAPSSRGAREFVEREVTDFARRNPGVVVYVNPRPCAMPRIVAEYLNGAVREENVNSKSVEEIKSLVQKLADQSG-LDVIRIRKP---FHTDNPSIQGQWTPSPTNGLPSTGCGP---------ENSGILLQLRCKHSKEPGALDRER----DRIGSSFGFQAQAE-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W1L1-1", "uniprot_id": "Q9W1L1_DROME", "id": "Q9W1L1-1", "name": "Large ribosomal subunit protein mL43", "aln": "MSNSHLFLKSGFPRAPLQNGLGRYVCQLQRITLKFCKNNGSSRGMRDFIENHLLDFAKENPGIVVYVKPRRHRTPVLVGEYLNGEREWMSCRNSTQEEISKWIDLLKTQNGSSSSLRLRKM---WHTEVPSIQGPWTPFLLRSPDAQGQAYP------SAEASKPLDTPQTATEKLIELFRQQQLEAGEEAHDVLNKKRAE--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06090-1", "uniprot_id": "RM51_YEAST", "id": "Q06090-1", "name": "Large ribosomal subunit protein mL43", "aln": "-----MVVKAIARNSIGRNGVGAFVFPCRKITLQFCNWGGSSEGMRKFLTSKRLDKWGQEFPWIQFEVMRKSGHPLLRAEYTNGREKVICVRNLNIDNVENKLKLLKDSDG--DILRRRTKNDNVESLNSSVRGIWSPLHAAKRHRI--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :**:* :* ::::: ... **.* *.*: . * .: : : * * : .** ** . . . ::: . :. * ..* . :* *. .: .*::* * * ", "identical_positions": 24, "similar_positions": 42, "identity": "10.86%" }, { "cls_id": "homologset.agr.MGI:2137237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESN0-1", "uniprot_id": "NIBA1_RAT", "id": "Q9ESN0-1", "name": "Protein Niban 1", "aln": "MGGSASSQLDEGKCAYIRGKTEASIKNFSPYYSRQYSVAFCNHVRSEVEQQRDLTSQFLKTKPPLEPGTVLYEAELSQFAEDIRKWKDRYVVVKNDFAVESYENKEAYQRGAVPKSRILPAGGKVLTSEEEYSLLSDKHFPDPTASSEK-NSQPFLVLPKAFPVYLWQPYLRHGYFCFHEAAEQQKFSALLNDCIRHLN-HDYMKQTTFEAQAFLEAVQFFRQEKGHYGAWEVITGDEVQILSKLVMEELLPTLQTDLLPKLKGKKNDRKRAWFGLLEEAYNLVQHQVSEGLSALKEECRALTKDLEGTIRSDMDQIVNSKNFLTGKIRAMVAQPAENRCGESVQPFLASILEELMGPVSSGFSEVRALFEKEVDELSQSFHTTQDGAQLKECLDQLMKLPLDSVKMEPCYTKVTLLPERLLDLQSRFRFPHVDLVVQRTQNYMQELMENAVFTFEQLLSPYLQGEASRTAVAIEKVKLRVLKQYDYDSSTIRKKIFQEALIQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENIYEEILYQILLDETLKVITEAAILKKHNLFEDNMALPSESVSSLTDLKTSMGSNQASPARGASAILPGAPGDEAPGSEVFQGPEEKQQQPGVPGSLAREESASISGSSPPSGEDGQVSVSGVDNSAGNPLSADNSAGPLSSHLSEAEAGEPPKDEETAHKRPESSAVPGSLRELKELLT--VTVFVESAPEIGNDTLNGTPVPQEDKKEEEEEEESKIHPEASGPAAIQQDSCEESEVREREAHPMPLEAEAPGVNLGTLPEGRGPTSQSTGEGLTENTSCLGPIEEPSEAQGPTEEVLLATVSTQDSTE-AGGEAVHSVTVTPQEDATLSSNPICPVENNEGPQVSEDQEVLGGNDSPALA---MDTEQINDAHVYECHWEVEDAPSADILDVHDCDVGSPG----EW-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UW53-1", "uniprot_id": "NIBA1_MOUSE", "id": "Q3UW53-1", "name": "Protein Niban 1", "aln": "MGGSASSQLDEGKCAYIRGKTEASIKNFSPYYSRQYSVAFCNHVRSEVEQQRDLTSQFLKTKPPLEPGTVLYEAELSQFAEDIRKWKDRYIVIKNDFAVESYESKEAYQRGAVPKSRILPAGGKVLTSEEEYSLLSDKHFPDPTASSEK-NSQPFVLLPKAFPVYLWQPYLRHGYFCFHEAAEQQKFSALLNDCIRHLN-HDYMKQTTFEAQAFLEAVQFFRQEKGHYGSWEMTTGDEVQVLSKLVMEELLPTLQTDLLPKLKGKKNDRKRAWFGLLEEAYNLVQHQVSEGLNALKEECRALTKDLEGTIRSDMDQIVTSKNFLTGKIRAMVAQPAEQCCGESVQPFLASILEELMGPVSSGFSEVRALFEKEVDELSQSFHATQDSAQLKEGLQQLMKLPLDSVKMEPCYTKVTLLPERLLDLQSRFRFPHVDLVVQRTQNYMQELMENAVFTFEQLLSPYLQGEASRIPVAIEKVKLRVLKQYDYDSSTIRKKIFQEALIQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENVYEEILYEILLDETLKVITEAAILKKHNLFEDNMALPSESVSSLTDLKTAMGSNQASPARRVSAILPGAPDNELPSNEVFQEPEEKKEQPGVPGSLA------ISASSCPSGGDGQVSV---DHSAGGPLTVENTAGPLSSHLSEVEAGGTLKDEEPTCQSPEPSAVPGSLKELKKLLT--VTVSVESAPVVENDIHNGTPVPQENIKEEE----SKIHPEASHPAAIQQDSCEEREVREKEAQ--PLEAEAPGVDLGILPEGRGSTSQSTSGGLTENTSCPGPIEEPFEAQEPAEKVLPAIVSTEDSPQ-AGGEAEHSVTVTPQEDATLSSNPICPMESNEVAQASGDQEVLGGEDSSALG---MDTEQVNDTHEHACQWLVEDTLSTDILAVHDFDVSSPEQPSEEW-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZQ8-1", "uniprot_id": "NIBA1_HUMAN", "id": "Q9BZQ8-1", "name": "Protein Niban 1", "aln": "MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLKTKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILPAGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHEAADQKRFSALLSDCVRHLN-HDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQILSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRALTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSSGFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERLQDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAVAIEKVKLRVLKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENVYEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEK-QPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEE--------KEPSQAAAIHPDNCEESEVSEREAQ--PPCPEAHGEELGGFPEVGSPASPPASGGLTE------------EPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPICLSES----QVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVLLSHKDDVKEGEGGQESFPELPSEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FC82-1", "uniprot_id": "E7FC82_DANRE", "id": "E7FC82-1", "name": "", "aln": "MGASSSSLLDESKINYIRGRTEAELKNFSPHYRRQSCVAFFCHLKDEVEQHRAAQSQLLKQKVPPEASEVLYKDSMLYFDDN-RKWRERLVVVRADYSLELHDSQESYTKGTPARHKLLPTGGAVLTSEEKYTAVVDKDFPDPNGCKEE-ASVAMVVVPGPLPVYLRLPYRRDSYFCFHQEEKRARFVSILNDCIRHHN-QDFVKSTAHEVQAFLKAIHFYRQEKGHYESWDMLVGTDTQVLANLVLEDLLPSLQTELLPKLKGKKPERKRVWFATVEATYELVHEQLREGLESLKTECINASKQQEALIRSDMDQIINSQTFVETKLQALVSDPAMKYCSESVSPYLTSILEELMGPVSAGFQAVRQLLEDELTRICKDFPQGGVTEELQTALQQVGRD-----RMEDCYQHVNVLKEQLQELRNRFKFSNSSRVVHCTQGQMQQLMENAVYTFELLLQSALKDKPDKQASVMEKAKLRVLKQFDYDSSTVRKKIFQEALVDITLPAIKRSLAPACKTELQNFEQFVFADYTNFVQVENIYENILLNLLNNEVNKVVKEAASLKKNNLFADSTDLQCVSQSSLADSRTPPLSAPSSPPPVQASVTP----SRQPELMIHQISQQTTVIPVLK----------ITPETP---------------QADLPPTLLNSSSSLIPEVSSSEPANVSPAEESSSSQPE--STSSKVKDEDGSVS-------SDRAVYLNSTNTESPVPFVDASENG-------------------NVEEEASSSQSETK----CVQPDGPVEETVEKIVSVEAAPSSE-------------------EDGNDTQVSPVSPLDCDVPVGGAVALAADVVEK--CSVSADP--------------EEESADG------------VQSIRDLIMEVIEVEETVRPCAENLP-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B7L2-1", "uniprot_id": "A0A8M2B7L2_DANRE", "id": "A0A8M2B7L2-1", "name": "", "aln": "-MGASSSLLDETQSNYIKEQVDEKLKDFTPIYRKQYSVAYCSQIKDELEQRKEEHTQFLKQRPPPEAGKILFEEIVWYFDDG-RKWKERFIVIRACYVLEVHESYKSFLKGTPPQQRLIPTGGTILTAEDEYMELIDQCCPCTKNDRED-FAPPMVDMPGQFPVYLRLPYRQDSYFCFKDEDAQADFISLLADCVRHQNKADYLKKKTCEVKAFLKAFQLYREEKGQYESWDMLIGSDVRGLANLFMEDLMPYLEKELK----SKRTDKRKVWFATVESAYFLLQEHLFDRMTTLKEECKNKAKQQEALMRSDMDQITNSRTYLEGKLQALVSEPATKYCAEQVQPHLPALLEEVMGPISLGFTEARDLSEGMMEQLCEDFQDPQQEVELRQALFKMSKAN-----LQSCYEKVSGLKDHVQELQQTFNYS-IKGLVDSTEIYLKQLMENVEYSFELLVKKALLDPSVNFSEAMQKASDRVLKQFDYDSSTVRKRIIQEALVNITFPNIKKHLDPSFKEELPKFEQYIFADYSNFISVENVYEDIIQQILEKDVSTVVKEAASRKKFNLITESKYKFS--VSSLSSTPPGSAPSSPSRLNTSPSQRSPLPPSPLLTNGLTANRSVTVHSPNSENSTPMGRIDEGEYKTPIEGCSDDVFFTSETSTETKPELRTTTNAKEPSVSSSPVIVITEAKESPSSSAKAGDGSLSDLANKPTVIISPICKNTAGMEKLREVMESDDPALTKAKICDES------------------THPISVCLSIEDAEVGEVHKKMTGKQIMDLPEKAPKSCS--------------------------SPYLEDKTRPLDCVKEIRDLVVEVIEIEDTIKPNEDNND--------------------------------DDDDVDDDEDIQRFQELEATI-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::** *** : **: :.: :*:*:* * :* .**: ::: *:**:: :*:** : * .. :*:: : * :. :**::* :*:: : :* ::. ::: :*: .: :::*:** :**:*::* : *: * . *. : .:: :* :**** *: :..****:: : * ::* **:** * *::*. : *.:***:*.:::*:***:* :*:: * : : *::*.:*:*:* *:.:* .*: ::::.*:. :* :* *::.:: : : :** ** :* *. :******* .*:.:: *::*:*::** : * *.*.*.*.::***:***:* ** .* * * : .:.:.* :*: * :: . :: ** :*. * ::: :*:. *.:. . :*. *: :::****. ::** *:. * . . . . .::*.. *****:******:**:*:****::**:* ::: * .: * ** ::**::***::*:: ***:**:*: ::* .:. .*:.*** ** **: :. . ***:. . . .* .: . . : . * : * : . . *. *..: . ..: : . : . : . ::. : * . : . . . . . . . . : :.: ", "identical_positions": 193, "similar_positions": 273, "identity": "20.19%" }, { "cls_id": "homologset.agr.MGI:2137300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESM2-1", "uniprot_id": "HPLN2_RAT", "id": "Q9ESM2-1", "name": "Hyaluronan and proteoglycan link protein 2", "aln": "MPSWIPLPAFCCLLLPWAFTVFHKTLGNPAPHPGPHYLLPPIHEVIHSRRGATATLPCVLGTSPPSYKVRWSKVEPGE-LRETLILITNGLHARDYGLLGGRASLRRGHRLDASLIIKNVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYFEAKRACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLNARAPCGGHGRPGIRSYGPRDRSRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAVCRRRGAVVAKVGHLYAAWKFSGLDRCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYAEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESM3-1", "uniprot_id": "HPLN2_MOUSE", "id": "Q9ESM3-1", "name": "Hyaluronan and proteoglycan link protein 2", "aln": "MPSRIPLPAFCCFLLPWAFTSFHKALGNPAPHPGPHYLLPPIHEVIHSRRGATATLPCVLGTSPPSYKVRWSKVEPGE-LRETLILITNGLHARDYGLLGGRASLRRGHRLDASLIIKNVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYFEAKRACEEQDGRLATYGQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGHGRPGIRSYGPRDRSRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQASYGTYCYAEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZV7-1", "uniprot_id": "HPLN2_HUMAN", "id": "Q9GZV7-1", "name": "Hyaluronan and proteoglycan link protein 2", "aln": "MPGWLTLPTLCRFLL-WAFTIFHKAQGDPASHPGPHYLLPPIHEVIHSHRGATATLPCVLGTTPPSYKVRWSKVEPGE-LRETLILITNGLHARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCELINGIEDESVALTLSLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRGRPGIRSYGPRDRMRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYAEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NDB5-1", "uniprot_id": "A0A8M1NDB5_DANRE", "id": "A0A8M1NDB5-1", "name": "", "aln": "-MNFIALLLTSTCFFSCINAKYHYNQDK--DKELKYLLEPLVFAEVSARRGHAAILPCVMRFKPSHYRVKWTKLEPSSRGVENIVLITNGHADKQYGSVGPRAALQRAHDLDVSLRLSDLELEDDGSYRCELINGIEDESVIITLRIEGVVFPYQSQKGRYRFTFFDAKEACAEQDATLATYKQLYRAWTEGLDWCNAGWLIDGTVSYPVLHPRPACGGDLLSGIRSYGPRHKTRENYDAFCFTSTTKGSVFFIEGQLNFAEAERACRRDGAGLAKTGQIYSSWRFQQLDRCDGGWLEDGSVRFPIINPREHCGGIAEPGVRSFGFPSKSMRLYGAYCYR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.* . :: : :* .. : : * * :. : ::** :* ****: .*. *:*:*:*:**.. *.::***** : ** :* ** ::*.* **.** : .:.***:* ************** :** :********..:***:*.:::**.** ***. **** ***:**************::*:* **** .*..*** .********.: *:.********: *.***: *:*.::**. .*** ** :**.*::*::*:*. **:****** ******** .** :***:.:********* . **:*** ", "identical_positions": 176, "similar_positions": 90, "identity": "51.46%" }, { "cls_id": "homologset.agr.MGI:2137302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99NB2-1", "uniprot_id": "B3GN5_RAT", "id": "Q99NB2-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "aln": "MRVFVSSRRVKRWQ-FFHLFAICFILSFMVFWGPINNYIMSHMKSYSYRYLINSYDFVNDSLSLKHSSVQPH--HPYLINHREKCQAQDVLLLLFIKTAPENYERRSAIRKTWGNENYVQSQLNANIKILFALGT-PHPLKGKELQKRLIWEDQVYHDIIQQDFTDSFHNLTFKFLLQFGWANTFCPHARFLMTADDDIFIHMPNLIEYLQGLEQVGVRDFWIGHVHRGGPPVRDKSSKYYVPYEMYKWPAYPDYTAGAAYVVSNDVAAKIYEASQTLNSSMYIDDVFMGLCANKVGVVPQDHVFFSGEGKIPYHPCIYEKMITSH--GHSQDLQDLWVEATDPKVKDISKGFFGQIYCRLIKIVLLCRLTYRNSYPCRAAFA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGY6-1", "uniprot_id": "B3GN5_MOUSE", "id": "Q8BGY6-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "aln": "MRLFVS-RRVKRWK-IFHFFVTCFILSFMVFWSPINNYIMSHMKSYSYRYLVNSYGFVNNSLSLKHSSVQPH--YPYLINHREKCQAQDVLLLLFIKTAPENYGRRSAIRKTWGNENYVQSQLNANIKILFALGT-PGPLKGKELQKRLIGEDQVYKDIIQQDFIDSFHNLTSKFLLQFSWANTFCPHAKFLMTADDDIFIHMPNLIEYLQGLEQIGVRDFWIGHVHRGGPPVRDKSSKYYVPYEMYKWPAYPDYTAGAAYVVSRDVAAKIYEASQTLNSSMYIDDVFMGLCANKVGILPQDHVFFSGEGKIPYHPCIYEKMMTSH--GHLQDLQDLWIEATHPKVKNISKGFFGQIYCRLIKIVLLCRLTYRNSYPCWAAFA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYG0-1", "uniprot_id": "B3GN5_HUMAN", "id": "Q9BYG0-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "aln": "MRMLVSGRRVKKWQLIIQLFATCFLASLMFFWEPIDNHIVSHMKSYSYRYLINSYDFVNDTLSLKHTSAGPR--YQYLINHKEKCQAQDVLLLLFVKTAPENYDRRSGIRRTWGNENYVRSQLNANIKTLFALGT-PNPLEGEELQRKLAWEDQRYNDIIQQDFVDSFYNLTLKLLMQFSWANTYCPHAKFLMTADDDIFIHMPNLIEYLQSLEQIGVQDFWIGRVHRGAPPIRDKSSKYYVSYEMYQWPAYPDYTAGAAYVISGDVAAKVYEASQTLNSSLYIDDVFMGLCANKIGIVPQDHVFFSGEGKTPYHPCIYEKMMTSH--GHLEDLQDLWKNATDPKVKTISKGFFGQIYCRLMKIILLCKISYVDTYPCRAAFI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3S5-1", "uniprot_id": "B3G5A_DANRE", "id": "Q7T3S5-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A", "aln": "--MFMNCRRVKKWHFLQLLSMCCVMSVLMVCWEHVDHHVVSHVKSYSYRYLINSYDFINKSLSVSPEEAARFGSFPYLLDRRDVCKNKDVLLLLFVKSSPGNFKRRQAIRSTWGNESYISQELGVVVKVVFAMGVRPDRSGHKTMQRELRKEHMAHHDLIQQDFLDTFHNLTVKLLLQFRWTHENCAHAHFLMSADDDVFIHVPNLVHYLQELKSQNVRNLWVGHVHRGAPPVRKRDSKYYMPFDMYQWSSYPDYTAGAGYVVSGDVAAKIYQATQSLNASMYIDDVFMGICAIAAGVSPQEHVYFSGEGKTPYHPCIYEKMITSH--GHEGDIRYLWKAATGPQVEGISSGLLGKLYCAAVKMTLLCKPYFTNTYSCMAAFT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5XJP0-1", "uniprot_id": "B3G5B_DANRE", "id": "Q5XJP0-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B", "aln": "-MAVLKMPRFKKYH-LRLMITCFSTLLLMTYWEKIDNCVVTHVMSFSYRYLFNSFKFINSSFIVNPEDAIKYN-HRYLINHQTKCDNKDILLLLFVKSSSENFERRQAIRSTWGNETYIESTLGVTVKVLFALGLHPIPEERGKLKEDLMFEDQKYRDLIQQDFIDTFHNLTLKLLLQLGWKETYCHHAQFLMSADDDVFVHTPNLILYLQGFGQSNTRDLWIGGVHRGSPPNRDKESKYYVSRDLYPWLSYPDYTPGSGYVLSRDVVSRIYQASLTINASFHIDDVFLGICAKMMDVSPTDHAFFSGEGKAPHHHCIYSLMMTSH--GHVSDIHEMWRHARNAEDVLISSGLFRRLYCTAVKVRLLCVPFFSNSYPCKAAFFEEDT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24157-1", "uniprot_id": "BRN_DROME", "id": "Q24157-1", "name": "Beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase brn", "aln": "----------MQSKHRKLLLRCLLVLPLILLVDYCG--LLTHLHELNFERHFHYPLNDDTGSGSASSGLDKFAYLRVPSFTAEVPVDQPARLTMLIKSAVGNSRRREAIRRTWG---YEGRFSDVHLRRVFLLGT------AEDSEKDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQPELLFAGHVFQTSPLRHKFSKWYVSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLP-LFRFDDVYLGIVALKAGISLQHCDDFRFHRPAYKGPDSYSSVIASHEFGDPEEMTRVWNECRSANYA----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: . :::*: . .:. .: : : * :::*:: * **..** *** * .. :: :* :* :. : * : *::* :* *::.* * * :: : * ::.* : .*** :: *:: :* . :: .. .* *.: **:*:. : * : :* *.....:::* .. ::* *: : : :***::*: * .: . * . *. :::** *. :: :* . .: ", "identical_positions": 51, "similar_positions": 102, "identity": "13.18%" }, { "cls_id": "homologset.agr.MGI:2137336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GMN2-1", "uniprot_id": "BAIP2_RAT", "id": "Q6GMN2-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "------MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTFAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKAFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAAQLMQQMAN-SNGSILPSALSASKSN---------------------------------------------------------LVISDPIPGAKP-----------------------------------LPVPPELAPFVGR------MSAQENVPVMNGVAG--------------------------------------------------------------ADSEDYNPWADRK----AAQPKSLSPPQSQSKLSDSYSNTLPVRK------------------SVTPKNSYATTENKTLPRSSSMAAG--------LER----------------NGRMRVKAIFSHAAGDNSTLLS---------FKEGDLITLLVPEARDG-------------------------------------------------------------------------WHYG--ESEKTKMRGWFPFSYTRVLDSD------GSDRLHMSLQQGK---------SSSTGNLLDKDDLALPPPDYG-------TSSRAFPSQTAGTFKQRPYSVAVPAFSQ-GLDDYGARSVSR-------------NPFANVHLKPTVTNDR----------------SAPLLS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKX1-1", "uniprot_id": "BAIP2_MOUSE", "id": "Q8BKX1-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "------MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTFAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEETLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLMQQMAN-SNGSILPSALSASKSN---------------------------------------------------------LVISDPIPGAKP-----------------------------------LPVPPELAPFVGR------MSAQENVPVMNGVAG--------------------------------------------------------------PDSEDYNPWADRK----AAQPKSLSPPQSQSKLSDSYSNTLPVRK------------------SVTPKNSYATTENKTLPRSSSMAAG--------LER----------------NGRMRVKAIFSHAAGDNSTLLS---------FKEGDLITLLVPEARDG-------------------------------------------------------------------------WHYG--ESEKTKMRGWFPFSYTRVLDSD------GSDRLHMSLQQGK---------SSSTGNLLDKDDLALPPPDYG-------TSSRAFPTQTAGTFKQRPYSVAVPAFSQ-GLDDYGARSVSR-------------NPFANVHLKPTVTNDR----------------SAPLLS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQB8-1", "uniprot_id": "BAIP2_HUMAN", "id": "Q9UQB8-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "------MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQVA--SNGATLPSALSASKSN---------------------------------------------------------LVISDPIPGAKP-----------------------------------LPVPPELAPFVGR------MSAQESTPIMNGVTG--------------------------------------------------------------PDGEDYSPWADRK----AAQPKSLSPPQSQSKLSDSYSNTLPVRK------------------SVTPKNSYATTENKTLPRSSSMAAG--------LER----------------NGRMRVKAIFSHAAGDNSTLLS---------FKEGDLITLLVPEARDG-------------------------------------------------------------------------WHYG--ESEKTKMRGWFPFSYTRVLDSD------GSDRLHMSLQQGK---------SSSTGNLLDKDDLAIPPPDYG-------AASRAFPAQTASGFKQRPYSVAVPAFSQ-GLDDYGARSMSR-------------NPFAHVQLKPTVTNDRCDLSAQGPEGREHGDGSARTLAGR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAV5-1", "uniprot_id": "A0A8M2BAV5_DANRE", "id": "A0A8M2BAV5-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "MVLSEDSTMSRTDEVHRISENVYKNIMEQFNPCLRNFIAMGKNYEKALSSVTFAAKGYFDALVRMGELASESQGSKDLGDVLFQMAEVHRQIQVQLEDMLKCFHNELLSELEKKVDLDARYLTAALKKYQIEHKSKGESLEKCQAELKKLRRKSQGSKNPSKYGEKELQYVEAISSKQSELDTFIAEGYKTALSEERRRYCFLVDRQCAVAKNSSAYHGKGKDLLTQKIPVWQQACSDPNKLPDRAMMLTQQMTSGTS-TLLSSPLHSSKGN---------------------------------------------------------LVISDPIPGAQP-----------------------------------LPVPPELAAFMGGGLGQGRLMGPDGMSLVNGTTG--------------------------------------------------------------VHGDDYWTDGVSQGRPPSPQNPSQTQSQPQRQVSDVYSNTLPVRR------------------PQPAKNKTTVGETRTLPRSSSMAAG--------LEK----------------NGRSRVQAIFSHAAGDNSTLLS---------FTEGDIITLLVPEARDG-------------------------------------------------------------------------WHYG--ENEKNKMRGWFPFSYTRVLPDS------DGEKLRVNLHHGK---------SSSTGNLLEREDMSLPMPDYG-------LTARLLAQ-SLTQSRQRPYSMA--GFAQPALEDYDSQFAT-------------SDRALELYLRPSLMDDR----------------SAPLYY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GYK7-1", "uniprot_id": "A0AC58GYK7_DANRE", "id": "A0AC58GYK7-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "MVLTQASKMSRTDEVHRITENVYKSIMEQFNPCLRNFVAMGKTYEKALSSVTFAAKGYFDALVRMGELASESHGSKDLGDVLFQMAEVHRQIQMQLEDMLKSFHNELLTELEKKVELDVRYLNAALKKYQMEHKSKGESLEKCQAELKKLRRKSQGSKNPSKYGDKEMQYVETISSKQNELDNYISESYKNALSEERRRYCFLVDRQCAVAKTSNTYHTKGRDLLTQKIPLWQQACADPNKLPERAMLLAQQMSSGAAGTLGPSVHHTSKSN---------------------------------------------------------LTISDPIPGAKP-----------------------------------LPVPPELAALMGN--QQSRMMGADSVPIVNGSGV--------------------------------------------------------------HVGEDYQRWMETR-----AAHDKQSQ-QPHRHGGESFSNTLPVRK------------------VAPVKPKNTLAETQTLPRSSSMTTG--------LER----------------NGRTRVQALFSHAAGDNSTLLS---------FTEGDIITLLVPEARDG-------------------------------------------------------------------------WHYG--ENEKNRMRGWFPFSYTRLIAEP------DSNKLHVSLQHNR---------SSSTGNLLER-EMALPTPDYG-------MPTRFAQQQSTAHSRQRPYSVAVPGFSQQGLEEYESRFQARTMD-----PLQFSTFALTSRQRQRNAASK----------------QKPKLIITEELGSRLLH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQE6-1", "uniprot_id": "Q8IQE6_DROME", "id": "Q8IQE6-1", "name": "", "aln": "---------MEAEEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQS-GTGDIGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESYQKAVSTMKKQRKKKATPEN----TEKELRSLQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLERQCSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAAYESGYSTSNGHNNNNISSSSSSGNNNTSGNMRRLERIKDGDDDHLQGHGAQLKKSRSIDAPYGDMRTLHERENLSGLGGTGPAHYAQNSLPRAKSDFNLALVGTGQSSANKHKIIEEQLATLGDDQRGDQRPLVKALYAYMPSGENQLSFEEGDRIALVGGKAKGWQFGENLRTQHFGWFPVAYTNAEVAEVTTSGGRRYENMLMSYERNGGGSGSGSGGGGLRSYQQQQDYEAQLELMESHEATYRRRRNHSAEDSSPTRMFGDTIKQQKKYRPGSGANPRPGPPPTLPAPVPNGPQSQSSRMLNSSQSFCASNGGGVNAAVERRKQKLLNGVQSSKNHPSGKSGVAAKTSLHSSNDSGFANEPPPQPEVDYSDEEPATQRVAIRRRADTNSHTNTVPRDVASWTLNRNFRNSVDSQIDDKSLHRLSRQSGGVGKMRYDLIASDDEILQASSAGLKRTKSFWKFGGGRNGEDILAGMSLWQHRDLVAAPNLEEMRDRDDLERRLEEDRNGTLTKSHNSSSSQEKRERKDSLTSTELYGDEDENIYGVSPQQPPLQQQTQQHQQHQQHQQQQAQQHRSSYTPKSRMKIMKTIEIDIEEPTEAERMSTMRRGQSQDQQQQHRKLDKQVSGTGSQHKSLTLSRTKSNQQQQQQQQFPQSTDEGESDEHGTLKLSDVNNFFDGEGKNNSHGHGLVMKTVKRQDILKQYYTSEDEEDSDAELKSTSSDPYDCIVINDHLVRKDDKMRRHHQQQHQQMATNTLKKSSSKDQDSTLTRNSTASSGAPTATILPRTRLLKSSTSAGNNIGNSSATLERNSKGLAGNKSYGPWYDFWDQEQHGQKSASAKLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::*: :: :.**:.*:::*** *:::* **.* *** ..: *:: : :**.::. *.:* *: ::*..*:.:.:*:::** * : **.*: :** ** ::: * : : **: ::: : :: :*. : :** *:*. .:* :**:: :: :..:: :*: : :.**.*:::****: *::::**::** .** .*: :: ::: **: .:. . :* * . : .* :.:.* .:.:* *:. *: * . : : : .::.* :** . . . :.:*: :: . ..: * *.*: :. :*: .*: * * * :.::* : . :.: : * *. * . *::* .. : : * :.: :: . : *. *...: ***: : :: : . ** : ::: :. :* ..* .: : .: . ", "identical_positions": 99, "similar_positions": 202, "identity": "9.08%" }, { "cls_id": "homologset.agr.MGI:2137352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3L4-1", "uniprot_id": "D4A3L4_RAT", "id": "D4A3L4-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MTSAVLVDIRDEVTCPICLELLTEPLSIDCGHSFCQACIIGNSDNSVLNPEGKSSCPVCRTVYQPGSLRPNRHLAAIVKRLREVVLGPGKQLEVIFCALHGEKLQLFCKEDGKLICWLCERSLEHRGHHTFLMEEVAQEYQDMFQESLKKLRREQQEAEKLKALIQEKRESWKSQVEPERHRIQTEFNQLRSILDREEQRELKKLEVEERKGLSVIEKAEGDLIHQSQALKDLISDLEHRCRGSTVELLQDVGDVTKRSEFWTLKKPQALPTKLKSLFRAPDLKKMLRVFRELTDVQSYWVDVTLNPQTANLNLVLSKNRRQVRFVGAKLSEPSSLEEHYDCSVLGSQHFSSGKYYWEVDVTKKTAWILGVCSTPVEPMFSFSQYSSKQGAYSRYQPQSGYWVIGLQRKHEYRAYEDSSPSLLLSMTVPPRRIGVFLDYEAGTVSFYNVTNHGLPIYTFSKYYFPTALCPYFNPCSCVVPMTLRRPTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGE7-1", "uniprot_id": "TRIM6_MOUSE", "id": "Q8BGE7-1", "name": "Tripartite motif-containing protein 6", "aln": "MTSTVLVDIRDEVTCPICLELLTEPLSIDCGHSFCQVCIIGNSNNSVFGQGGRSSCPVCRTSYQPGNLRPNRHLAAIVKRLREVALCPGKQLEVIFCALHGEKLQLFCKEDGKLICWLCERSQEHRGHHTFLMEEVAQEYQDMFQESLKKLRREQQEAEKLKALIQEKRESWKSQVEPEKRRIQTEFKQLRSILDREEQRELKKLEVEERKGLSIIEKAEGDLIHQSQSLKDLISDLEHRCQGSTVELLQDVGDVTKRSEFWTLRKPQALPTKLKSLFRAPDLRKMLKVFRELTDVQSYWVDVTLNPQTANLNLVLSKNRRQVRFVGAQLSEPSSLEEHYDCSVLGSQHFSSGKYYWEVDVSKKTAWILGVCSTPVDPMFSFSQYSSKQGAYSRYQPQCGYWVIGLQCKHEYRAYEDSSPSLLLSMTVPPRRIGIFLDCEAGTVSFYNVTNHGLPIYTFSKYYFPSALCPYFNPCSCIVPMTLRRPTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C030-1", "uniprot_id": "TRIM6_HUMAN", "id": "Q9C030-1", "name": "Tripartite motif-containing protein 6", "aln": "MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIPMTLRRPSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.******:*************************.** *. :**:. *. *****:* ****.******** **:*****.* *****:.::** *********:****:******** *********:********: ********:.*:******.*:*:**: ***.*:***: ******:***.**** ********* **:*** :**:**.**:**:*:*::******:**:***:******.***:*******:**:******:*:******::**:* *****************:********:***********::* **.**:****************:******:***********..: * ***.:::.::.********.******** :***********************:*:*** **************:***********::********.*::*******:*", "identical_positions": 382, "similar_positions": 83, "identity": "78.28%" }, { "cls_id": "homologset.agr.MGI:2137353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNJ9-1", "uniprot_id": "D3ZNJ9_RAT", "id": "D3ZNJ9-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MATVGPRTGPNSGAEALALAAELQGEATCSICLEFFREPVSVECGHSFCRACIMRCWERPGAG-TGTVTRTLPCPLPCPQCREPARPSQLRPNRQLAAVASLLRRFSLPPTVPGESGTPAVAAPAAAARCPQHGEQLKLYCQDDGRAICVVCDRAREHRSHAVLPLEEAVQEAKELLDSRMKALKKVLEDYEAFRSTEERESKELLKQMAAEKEKVGAEFQALRAFLVEQEGRLLSRLEVLSREVTQKQNENLAQLEGDITQLSKLSSQIQETAQKPDIEFLQEFKNTLSKCSSVPSSKPTTVSSEMKNKVWNVSLKSFVLKGLLKKFKEDLQGELEKEEKVELSLDPDTANPRLILSLDLKSVRLGQRAQDLPNHPRRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWAMQLNNGQYWAVTSPERTQLNCGQLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLRIWP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923T7-1", "uniprot_id": "TRIM7_MOUSE", "id": "Q923T7-1", "name": "E3 ubiquitin-protein ligase TRIM7", "aln": "MATVGPRTGPNAGAEALALAAELQGEATCSICLEFFREPVSVECGHSFCRACIMRCWERPGAG-TGTATRTLPCPLPCPQCREPARPSQLRPNRQLAAVVSLLRRFSLPPTAPGERGTPAVPARAAAARCSQHGEQLKLYCQDDGRAICVVCDRAREHRSHAVLPLEEAVQEAKELLDSRLRALKKVLEDYEAFRSTEERESKELLKQMAAEKEKVGAEFQALRAFLVEQEGRLLSRLEVLSREVTQKQNENLAQLEGEITQLSKLSGQIQETAQKPDLDFLQEFKSTLSKCSSVPSSKPTTVSSEMKNKVWNVSLKSFVLKGLLKKFKEDLQGELEKEEKVELTLDPDTANPRLILSLDLKSVRLGQRAQDLPNHPRRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWAMQLNNGQYWAVTSPERTQLNCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLRIWP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C029-2", "uniprot_id": "TRIM7_HUMAN", "id": "Q9C029-2", "name": "E3 ubiquitin-protein ligase TRIM7", "aln": "MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLRIWP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*******.:**********************:****************** ********* .*:.**: * *************************.:********.:.*** *: *..* ****** **** :**********************.******:**********:**::.*** *** *.*****::************:**********************.*** *****:********** :********.**********::******.***:**.**..*******************:*****:********:***********:*****************.****:********* ********************************************************:***.***********: *.**:******************************************************", "identical_positions": 446, "similar_positions": 49, "identity": "87.28%" }, { "cls_id": "homologset.agr.MGI:2137354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZY8-1", "uniprot_id": "TRIM9_RAT", "id": "Q91ZY8-1", "name": "E3 ubiquitin-protein ligase TRIM9", "aln": "MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQT-PESESPQSRRASGSG-VSDYDYLDLD--------------------KMSLYSEADSGYGSYGGFASAPTTPCQ--------KSPNGVRVFPPAMPPPP---THLSP----ALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRTMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT--LTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKAS-------SPVPATPILQLEECCTHNNSATLSWKQPPLSTVAADGYILELDDGSGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVA------------------------------------------------------------------------------------------------WFAFD---PGSAHSDIIFSNDNLTVTCSSYDDRVVLGKTGFSKGVHYWELTIDRYDNHPDPAFGVARIDVMKDMMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKTLTFFVNNEQQGPIAFENVEGLFFPAVSLNRNVQVTLHTG----------LPVPDFYSSRASIA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C7M3-1", "uniprot_id": "TRIM9_MOUSE", "id": "Q8C7M3-1", "name": "E3 ubiquitin-protein ligase TRIM9", "aln": "MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQT-PESESPQSRRASGSG-VSDYDYLDLD--------------------KMSLYSEADSGYGSYGGFASAPTTPCQ--------KSPNGVRVFPPAMPPPP---THLSP----ALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRTMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT--LTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKAS-------SPVPATPILQLEECCTHNNSATLSWKQPPLSTVAADGYILELDDGSGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEAAGAHETKPMKDTDSEEQTLPFPVPSERLPLRRMSPFSSTLNLQPSFPGRSYFDFRSSPHQLSLHSSLQSLNAPGCNFETQSASYSQLVDIKKLLAVAWFAFD---PGSAHSDIIFSNDNLTVTCSSYDDRVVLGKTGFSKGVHYWELTIDRYDNHPDPAFGVARIDVMKDMMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKTLTFFVNNEQQGPIAFENVEGLFFPAVSLNRNVQVSLWAPGLRACSGCYFKVCPGAVKSPQAPAP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C026-1", "uniprot_id": "TRIM9_HUMAN", "id": "Q9C026-1", "name": "E3 ubiquitin-protein ligase TRIM9", "aln": "MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQT-PESESPQSHRAAGSG-VSDYDYLDLD--------------------KMSLYSEADSGYGSYGGFASAPTTPCQ--------KSPNGVRVFPPAMPPPA---THLSP----ALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT--LTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKAS-------SPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVA------------------------------------------------------------------------------------------------WFAFD---PGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTG----------LPVPDFYSSRASIA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3Y3-1", "uniprot_id": "A0A8M2B3Y3_DANRE", "id": "A0A8M2B3Y3-1", "name": "", "aln": "MDEMEEELKCPVCGSFFREPIILPCSHNICLACARNILVQT-PDAESPQSSRASGSG-VSDYDYLDLD--------------------KMSLYSEADSGYGSYGGFVSAPTTPCQ--------KSPNGVRVFPPSMPPPQQAQHHLLPHTG-VLPPVPRNSCLTCPQCHRSLTLDDRGLRGFPKNRVLEGVVDRYQQSKAAALKCQLCEKSPREATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRISRRASPRKISTCTEHELENLSMYCVQCKTPVCYQCLEDGKHSTHEVKALGAMWKLHKGQLSQALNVLSDRATEAKEFLVQLRNMVQHIQENGVEFEACLVAQCDALIEALNRRKAQLLSRVTKEHEHKLSVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHMTENQWGKGS--LTPRMSSDFDLTLDSGPLLQTIHQLDFVQMK-----------VPAAPILQLEECCTQTSSATLSWKQPPLSTIAVDGYILELDDGTGGQFREVYVGTEMICTVDGLHFNSTYKSRVKAFNSSGVGQYSKTLVMQTSEIA------------------------------------------------------------------------------------------------WFTFD---SASAHPDIILSNDNLTVTCNSYDDRVVMGNTGFSRGVHYWEMTIDRYDNHPDPAFGVARADVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTDGGISKGATVGVLLDFTRGILLFLINDEQQGPVAFNTLEGMYYPAISLNRNVQVTLHSG----------LPIPDFYTPGESEAAGSVC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MRI4-1", "uniprot_id": "TRIM9_DROME", "id": "M9MRI4-1", "name": "E3 ubiquitin-protein ligase TRIM9", "aln": "---MEDELRCPTCKQLYANPVLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHGNGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCCSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCAR--EALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKP------RGAAQQRESVCGEHEET-LSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFIQRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDDAALARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQPP--NHSFVEGYVLELDDGSGGEFREVYCGKETICTVDGLHFNSMYNARVKAFNSAGEGEYSELIGLQTAEVA------------------------------------------------------------------------------------------------WFTFDPVLSGGAGSGLIFSKNNATVSVEGWEHRVALGSVGFSRGVHYWEFTIDNYTADTDPAFGVARIDVARNKMLGKDEKSFAMYIDRQRSWFQHNSIHERRVEGGITTGSTIGVLLDLERHTLSFLVNEMPQGSVAFRDLYGVFYPAVSINRGVTLTMHTA----------MDAPKMDYF----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 283, "similar_positions": 244, "identity": "32.53%" }, { "cls_id": "homologset.agr.MGI:2137355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1H278-1", "uniprot_id": "TRI11_RAT", "id": "B1H278-1", "name": "E3 ubiquitin-protein ligase TRIM11", "aln": "--------------------------------------------------------------------------MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP-----EGPYACPECREVSAQRNLRPNRPLAKMAEMARRLHPPSPVPQG----------VCAAHREPLTTFCGDDLSLLCPTCERS-EHWAHRVRPLQEAADDLKGRLEKSLEHLRKQMEDAMLFQAQAEETCALWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQKLEEEELEVLPRLREGAARLGQQSTQLAALVSELESRCQLP-ALGLLQDIKDALCRVQDVKLQPPAVVPMELRTVCRVPGLVETLRRFRG-------DITLDPDTANPELVLSEDRRSVQRGEQRQALPDSPERFDPGPCVLGQERITSGRHYWEVEVGDQTSWALGVCKETVNRKEKGELSAGNGFWILVFLG---SFYNSNERAFSPLRDPPKRVGIFLDYEAGHLSFYSATDGSLLFIFPETPFSGTLRPLFSPLSSSPTPMTICRLIGVSGDTLGPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PQ2-1", "uniprot_id": "TRI11_MOUSE", "id": "Q99PQ2-1", "name": "E3 ubiquitin-protein ligase TRIM11", "aln": "--------------------------------------------------------------------------MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP-----EGPYACPECRELSAQRNLRPNRPLAKMAEMARRLHPPSPVPQG----------VCAAHREPLTTFCGDDLSLLCPICERS-EHWTHRVRPLQEAADDLKGRLEKSLEHLRKQMEDAMLFQAQAEETCALWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQKLEEEELEVLPRLREGAARLGQQSTQLAALISELESRCQLP-ALGLLQDIKDALCRVQDVKLQPPAVVPMELRTVCRVPGLVETLRRFRG-------DITLDPDTANPELVLSEDRRSVQRGEQRQALPDNPERFDPGPCVLGQERITSGRHYWEVEVGDQTSWALGVCKETANRKEKGELSAGNGFWILVFLG---SFYNSNEPAFSPLRDPPKRVGIFLDYEAGHLSFYSATDGSLLFIFPETLFSGTLRPLFSPLSSSPTPMTICRLIGVSGDTLGPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F44-1", "uniprot_id": "TRI11_HUMAN", "id": "Q96F44-1", "name": "E3 ubiquitin-protein ligase TRIM11", "aln": "--------------------------------------------------------------------------MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP-----EGPYACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQG----------VCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLP-ALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG-------DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFLG---SYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGSGDTLAPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GIM4-1", "uniprot_id": "A0AC58GIM4_DANRE", "id": "A0AC58GIM4-1", "name": "", "aln": "MRRHVQTSLTKSDVMRETPANFQQDQNPETPPILSPSQQESQSRRARRTEQSMSSSLPAQNKMDKQKLRPEIPPRVSKSSAQRLSRDLTCSICLDLFKQPVSLPCDHTFCEACITSYWSGPRVKCQAGSGSCPQCRKVFHGKSYRPNRIVANIVESYCQGMEESGVRLGAVSEPAPTAPLCMRHREELKLYCEEDQELVCLVCGISQDHRAHTLVCVQDAQKRYRASLTTSANALQKELNTALECERETEEEVKKLKDHTADLKQRIEAQFSELHQFLYQEEKLLQVKLKTEERRELIRLDEHKALLSVEISRLRRAVNDIEDKLSEQDPYTLLRSIKGLLQRQPPKFERPTLTPPSLCEGRFAGPLQYRVWKSLKGSIYPVPSAITFNSKTANPWLSLTSSLTCVRYQTFNSSVQDNPQRFNAALSLMGGQGFTKGRHYWEVEVYSSTVWTVGVARESVTRKGVINTMPANGFWTLSLSYGVQYMAGTSPPTLLSLEEPLARIGVYLDYKRGLVSFYNAESMTHLYTFRDT-FTETLFPYFN--LGFLDKVHENEPLKVFMPKI---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : .*..: **:**** *.:** *.*.**. ** *. * *. :**:**:: :. **** :*::.* : * * * :* *** * :* :: *:* * * :* :* : :*:* . :. * .* : *:*::: *: : :::* :. . . :*.: .:*..*:::* :**: * :*: ** . * ** * * *. : ::* : ::*.: . . **:.**. * * :*. . * . * .. : ::* :*::..**** * *:.. .*: ..:: *.*:**:.. .::* : :*.********* . * *::**.:*...** : ..**** * : .:. :: .*.:* *:*::***: * :***.* . : *: * : *: ** * *. . : . .: ", "identical_positions": 134, "similar_positions": 155, "identity": "23.59%" }, { "cls_id": "homologset.agr.MGI:2137356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95361-1", "uniprot_id": "TRI16_HUMAN", "id": "O95361-1", "name": "Tripartite motif-containing protein 16", "aln": "MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGS--------------------------SEKLGRETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQ-EHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKN-TEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLEN-YKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q309B1-1", "uniprot_id": "TR16L_HUMAN", "id": "Q309B1-1", "name": "Tripartite motif-containing protein 16-like protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELETMAAISNTVQFLEEYCKFKN-TEDITFPSVYIGLKDKLSGIRKVITESTVHLIQLLEN-YKKKLQEFSKEEEYDIRTQVSAIVQRKYWTSKPEPSTREQFLQYVHDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDQKGEERSSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFWRLGVYIDFPGGILSFYGVEYDSMTLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99PP9-1", "uniprot_id": "TRI16_MOUSE", "id": "Q99PP9-1", "name": "Tripartite motif-containing protein 16", "aln": "MAELDLIAPGPLTGVTAHPLAPLGPDP-------VSAIPVEKEDADP--------------------------LSKSGEETQEQGHDPAELGAP-GEEDQILCDFCLGASR-VRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPAKDQDLRTCPAHHSPLVSFCHTHQQCICQECGEGEHRGDSTVSLDAARRNKEVDLRCMQLDLEQKLKLNENAIARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQADVMVFLEEKEQAALNQVNSIKTHLEHRSLEMEKSKQELERLAAISNTVLFLEEYCKLKK-TEDTASPSIYIGLKDKLSGIRKVITDSTLNLIQLLES-YKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQEDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVELSGGGTYVGLTCKGIDRKGEERNSCISGNSFSWSIHWNGKEFTAWHSDTETPLKVSPFRRLGIYVNFPGGILSFYGVEYDAMTLIHKFDCKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAGSSVEAAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P9M9-1", "uniprot_id": "A0A8M1P9M9_DANRE", "id": "A0A8M1P9M9-1", "name": "", "aln": "MSAMVLTAELPACSMTSEIPKEEKIEENRPKYTEVEDKKIQVNGSPPEKHTEGEKDVKTIEESKIQKDLKEIEVNKESKDPQKDDEDDEEEEEEVLGPDVVTCDSCIDKP--CRAKKSCLTCLVSYCESHLRPHLENAKFQSHRLVDPLRDIERRTCEAHRSPLELYCC--MCCLCPACVTEEHLGHQALPIAEARRNIEKELQDKQTEMLKTMTAAENAINKLQVNTVSIEGSVQEVRAVMEEQFSILQAAVEQVKRDVCELLEAEERQALRQADGIRVHLEQRCAELKKTQSRVQKISKNKHDIHFLQEYSEWKKEAVDVSLPGVYIGLVDRLQAFSHVIVRSTNRMCDNLHSSYTNKLKDTCKNDNVGIKTTVFAVMAAKKNMMLPDPKTRDDFLQYVTPLSLDANTAHVFLRLTEECKKVTNTTPWQHSYPDLPERFQDFKQVLTQESFYLGRHYFEVDMKGEGTHVGLTYKSIDRKGSQSNSCIAGNNFSWCLQWNGRSFSAWHSDVETPLSCPKTTHIGIYVDYSGGLLAFYDVENG-MTLIHKYQAEFLEPLYPAFWLPKKENVVLLEPGAASPLSSPSPSPDASTK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. * ***.:.: :* :** :*: ** *.:.*:.*** *. *::*::..:: :: .: : **:**.: *: : * : *.:*:** *:*..: :**. ** .: : *.. *.:**:: .:::: .*:* * *:: * *:* **::****. :::*.:*** :*** *: :********:*.*****.** .::***:*:*:** *:****:: * **:**** *.**:**.: .***:**.***.::***:.*:**:** ****. ::*:*:::.**:*:**.** . ***:**: .:* **:*.****.****.: : . .* ... . ::. ", "identical_positions": 147, "similar_positions": 132, "identity": "24.75%" }, { "cls_id": "homologset.agr.MGI:2137357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0K4-1", "uniprot_id": "A0ABK0M0K4_RAT", "id": "A0ABK0M0K4-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "MAENKGGGEAESGGGGSGSAPVTAGAAGPTAQEAEPPLAAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSSSAPAASVPAASVGSAVPGGAASTPAPAPVPVPVPVPVPAPAPAPAPAPAPAPGPSSGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP-----GGSNGDVQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGTSG--QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVG-QVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRLQQPPAPVPTTTTTTQQ-------------------------------HPRQAAPQMLQQQPPRLISVQTMQRGNMN--CGAFQAHQMRLAQNAARIP-GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSAHN--PINPTSPTTATMANAN--RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKSAHSFKSDQVKVKQEPGTEEEICSFSGAVKQEKTEDGRRSACMLSSPESSLTPPLSTN--LHLESELDTLTSLENHVK--TEP--ADISESCK----------QSGLSSLVNGKSPIRNLMHRSARIGGDGN------SKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFP--SGDWICTFCRDIGKPEVEYDCDNMQHSKKGKTAQGLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPVSIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN-------------------EMMKVVQVYADTQEINLKADSE------VAQAGKAVALYFEDKLS--EIYSDRTFAPLPEFE-QEEDDG-------EVTEDSDEDFIQPRRKRLKSD-ERPVHIK--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PP7-1", "uniprot_id": "TRI33_MOUSE", "id": "Q99PP7-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "MAENKGGGEAESGGGGSGSAPVTAGAAGPTAQEAEPPLAAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSSSAPAASVPAASVGSAVPGGAASTPAPAAAPAPAPA--PAPAPAPAPAPAPAPGSSSGPPLGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP-----GGSNGDVQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGTSG--QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVG-QVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRLQQPPAPIPTTTATTQQ-------------------------------HPRQAAPQMLQQQPPRLISVQTMQRGNMN--CGAFQAHQMRLAQNAARIP-GIPRHSAPQYSMMQPHLQRQHSNPGHAGPFPVVSAHN--PINPTSPTTATMANAN--RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKSAHSFKSDQVKVKQEPGTEEEICSFSGAVKQEKTEDGRRSACMLSSPESSLTPPLSTN--LHLESELDTLTGLENHVK--TEP--TDISESCK----------QSGLSNLVNGKSPIRNLMHRSARIGGDGN------SKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFP--SGDWICTFCRDIGKPEVEYDCDNMQHSKKGKTAQGLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPVSIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN-------------------EMMKVVQVYADTQEINLKGDSE------VAKAGKAVALYFEDKLS--EIYSDRTFTPLPEFE-QDEDDG-------EVTEDSDEDFIQPRRKRLKSD-ERPVHIK--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPN9-1", "uniprot_id": "TRI33_HUMAN", "id": "Q9UPN9-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVST------------------PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP-----GGSNGDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGASG--QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVG-QVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQ-------------------------------HPRQAAPQMLQQQPPRLISVQTMQRGNMN--CGAFQAHQMRLAQNAARIP-GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNT-TINPTSPTTATMANAN--RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPGTEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTN--LHLESELDALASLENHVK--IEP--ADMNESCK----------QSGLSSLVNGKSPIRSLMHRSARIGGDGN------NKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFP--SGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN-------------------EMMKVVQVYADTQEINLKADSE------VAQAGKAVALYFEDKLT--EIYSDRTFAPLPEFE-QEEDDG-------EVTEDSDEDFIQPRRKRLKSD-ERPVHIK--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6E2N3-1", "uniprot_id": "TRI33_DANRE", "id": "Q6E2N3-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "-MEVEASGTEDNGDGGAKEPEAVVSIDTETKEAADEAKSQETVPQTPTTSSDSSSSGGGGEATDGTPNAESADPPPPPPPPPPPPPSTPADSTAAAASP-------------AVLTEMSPPPPASTSSSSSTPAAPINLLDTCAVCKQSLQNR-DCEPKLLPCLHSFCLKCIPQPDRKITMPVQ-----GPHGQDTRIVNVMRCTVCHQDYKQIDMVDNYFVKDTSEATNTSVENSTQVCTSCEDNASAIGFCVECGEWLCKTCIEAHQRVKFTKDHKIRKKEEVSPESVGTSG--QRPVFCPVHKQEALKLFCETCDTLTCRDCQLLEHKEHRYQFLDEACQNQKGIIATFMTKLQEKRGLVEYSASEVQKRLKEVAETHKKVEHEIKIAVFTLINEINKKGKSLLQQLESVTKDRSMKLLSQQRDISVLAQQIIHVLNFTNWAITNGSSTALLYSKRLITYQLRLIMKARVDAVPPANGAVRFFCDPTFWAKNVVNLGNLVIEKVAPTAPPSNMMVNQQISPGHNHPGKHSGQINLAQLRLQHMQQAAIAQKHQQQHQHHQQQQHQHQHQQQQQQQQQQQQQQQQQQQQQQHQQQIQQQMRIASQMSQHPRQGAPQMIQQPPPRLISMQALHRGGVNGSSHMFPPHHLRMVSAQNRMPSAQPRLNGQPYPMMQPQLQRQHSNPGHAGPFPVASLHNISAANPTSPTSASMANAHMHRGPSSPVITPIELIPSVTNPENLPCLPDIPPIQLEDAGSSTLDNILSRYISANAYP--TVGPTNPSPGPSTHSPGSSGLSNSHTPARPSSTSSTGSRGSSGTT------------VDQVKVKQEPGVEEECSYSGANVKTERTKDGRRSACMMSSPEGSLTPPLPILGSVSTGSVQDILRTLGENVK--SEPQSDNLSSCTN----------PNSRATLTNGTSGSNGGQRGGATNANSQTTA----GKEDDPNEDWCAVCQNGGELLCCDHCPKVFHITCHIPTLKSSP--SGDWMCTFCRNLANPEIEYNCDDDPPRNKEKNEMAMSPEEQRRCERLLLHVFCH-ELSTEFQEPVPTSVPNYYKIIKHPMDLTLVKRKLQRKHPLHYKSPKEFVSDVRLVFSNCAKYN-------------------EMSRIIQVYDEEKQSNVQADSE------VAEAGKAVSLYFEERLL--EIFPEQTFPVVMEKETQIEAEK-------EDSDDSDDDIIQPKRKRLKVDTEMLLHIK--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGE5-1", "uniprot_id": "A0A0B4KGE5_DROME", "id": "A0A0B4KGE5-1", "name": "", "aln": "-----------------------MDMDLEQLKNDFLPLIAGIKQEQ--------------------LDAVPTDALPQMSTPNTASGAPTTSSLSSSS-----------------LSLSNPCDSAEKRSESNSSASAKFTLFKCVYCAQLLGSN--DRPKLLECLHVACAQCVSTKFSELDRSLPPLIHCPVCDNASQQEFIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQKSSAAASIQCSSCSDGAVATSWCVDCSEYICDSCVQAHQRLKITKDHTIKPKDEANNEQLAGAAGVDKLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRDHKYKFAHEIATESRQALSTLVSEINYKRFLLSSATKVIDDRQQLIHDKKKDLIKEITAMAVKITNTVNTRGKQLIMRLNEVCDSKLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSSKKSLVRHLQKLKCQRAD-IPNPEIPVRIQVQLNQVSDLQKVISQLGIIIVDGKPYPPTPSPN--GTPQPQHPPRQPPSPNMAPPLRPGLPPGMPAGLSPNGPPVNFGPQNGPPLYSNAAQQQFNNLSMSRSFPGDGSGKVRFGGMPPVG----MQRHGQPHVSSSTHP--QNMDISLRGLLN-NQAAQSPNAHMAFNGPPSYPGGPQGAPAPAHQPMGPQMR-PHFMPGQQG-FSQGGGPGGGPRDANFMNSNARFQSQYQRMANHAQQAAAAAAMAGAAGGGGGQIPSPGALQRPQMMSNPMQNVSAMQNSLGFHG--SQAGFNTGPPQTSPQLGGGGMHSLAKWHIPQSAQQSNMCSQQGPLLPFANGRQTSENFKISLKSPNTLKNSTPPSLGGGGAGHQGHGNGSSSAQLNAAALGLGPAVSILSNVTSTNPKTPSPSTHENTKDFTEPIDKVRDDSINDLIATIAKLDSNGVQVLPEGRTKTTSPQVHSSTDLSNTQEVNNKNEQKDDPNEDWCAVCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLCVNIKELTKTEGSEKSSSGE-------LSALELRILQRICLELYCQYEQSLNFREPESPANTSYYEIVSSPMSLDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQEDTKTYSNAKYLENFFEEQLAKWLPQFEGTKPQGKRNTSNSPALLGVNATGSPSPIENGRKSCGSASLGDSDGACLPAKRARRSAHEXNELMPGGKGTDGEQQAETGQERRQEEQQQLPAFLEEMDLEMPQRPHSLGSSVIQESADYVLQLLHAYAAAFGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * .:.. . * .. : ... :: : . .* * . . ... * .*. * * * .. .**** *** * :*:. :: .: . : :: . :: * *. : . : ..* : *:**.*.* * .:**:*.*::*.:*::****:*:**** *: *::.. *.:. :. :: :* :* ** *.******* ******** :*::*:*:* .* :.: : .::::: *: : ::. ::.* : : :.:* : :**. ..: * :*.:**.*: :*:.* ..: *:.::. : *: : * ::* : *: .**. *:* **: :. :*: : * * :* .: .:*: : . :. :.:* * ... . .* :* : . . *:* : * : . ** *:. *:: .. * .:: ** :* .: . * . . : * *::: * **: * *. . . . :.. .: : ::: * .. . :. : : . :*. .:* : *..::*: : * . . . *..* :: . *..*: . . * *:..:. .. *. . . :. :. .. .: ... *:. :.:. .* *.:. : . ::.* ** ... : .. * :* : . .: .. :.*********** :**:*:**::****** .**:*:: * * * .* * :* :: : ..:. : :*. : * :*: * ::*: * * :*:** . : ..**:*:. **.* :: :*: . . **: **:****:*.* : :: : : : : . : *: * :*.. .: : : . : . : . . *.::: :.:* : : : .:: ", "identical_positions": 205, "similar_positions": 373, "identity": "15.89%" }, { "cls_id": "homologset.agr.MGI:2137359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA88-1", "uniprot_id": "D3ZA88_RAT", "id": "D3ZA88-1", "name": "", "aln": "MASTDQTDVQKEATCPVCHVLLIKPLNLGSGHHVSQACLTVK-KTAVTNPRGKSLCPMCGNRFSFENLQANKHLADVVERLREVKLSPDIGKKGDLCVHHGEKLLLFCQEDKKVICWVCERSQEHRGHHTFLRDEAVRECQENLQEALKRLRKEQEKVETFEADIKEDRISWKHQIQTERQRIQTGYNQLRRILDKEEQNELKRLREEEQMILDSLAGAEAELAQQSQLVEELISDLERRCEWSDTELLQDVSGILKWSQIWTLKKPKAVSKKLKMVFQAPDLSGMLQKFRELTAVRAYWADFTFNPENLNLNLILSEDHRQVTSVPIWPFKCCNNGILGSKCFLSGKHYWEVDVSEKNAWTLGVYSR--KRTLKFDVRRCSKSQPNGYHRYKPQNGYWVIGLQDGSKYSIFEDSSNCGPTVLNPFVATPLHRIGVFLDCEEGIVSFFNVTNHGSLIYKFTQCRFSQPAYPYFNPWDCPAPMTLCPRNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PP6-1", "uniprot_id": "TR34A_MOUSE", "id": "Q99PP6-1", "name": "E3 ubiquitin-protein ligase TRIM34A", "aln": "MASTGLTNIQEKTTCPVCQELLTKALSLGCGHRVCQACLITK-KNAVINPREKSSCPVCGTRFSLENLQANKHLANVVERLGEVKLKPDIGTKRDLCVHHGEKLLLFCKEDKKAICWVCERSQEHRGHHTFLWEEAVRECQENLQKALTRLRKEQEKVETLEADIKEDRLSWKCQVQTERQRIQTGFNQLRRILDKEEQRELKRLREEEQMILDSLAGAEAELAQQSQLVEELISDLELRREWSDTELLQDMSGILKWSQIWTLKKPKAVSKKLSMVFQAPDLSGMLQKFRELTAVRAYWDNFTFNPENLNLNLILSEDHRQVTSVSIWPFKCCNNGILGSKCFSSGKHYWEVDVSEKKAWTLGVYTR--KRTLRFDVRQR-KGQPNGYHRYKPQNGYWVIGLQHGSKYSIFEDSSNCDPTVLNPFVATPLHRVGVFLDCEEGTVSFLNVTNHGSLIYKFSQCCFSQPAYPYFNPWDCPAPMTLCPLNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYJ4-1", "uniprot_id": "TRI34_HUMAN", "id": "Q9BYJ4-1", "name": "E3 ubiquitin-protein ligase TRIM34", "aln": "MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQ-NLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPPSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. ::*::.***:* ** :.*.*..** :.:**: .. * ** . ** **:** :*:*:****:***::**** ****.** *.* *** **********:**:*.***:************.* :*..:****:** .*.**:**:*:.*.:****:*:: *** *:********* ::*** **::***.**:**.***: **.:* ** **.**.***.*****:* * :** *****:***:***:** ***** *****. **:***** *** ********.** :.*:*. ******:****:*** **.****:* * *:***: * ***********:*.** **** * .* ::: **: : * * * :*:* ********. .**.:**:* ...* **. :*.* *:***** * * ***:***.********::* ****.*******:********* .:", "identical_positions": 305, "similar_positions": 111, "identity": "62.37%" }, { "cls_id": "homologset.agr.MGI:2137361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIH3-1", "uniprot_id": "S28A3_RAT", "id": "Q8VIH3-1", "name": "Solute carrier family 28 member 3", "aln": "MSRSDPDPGKNSEPSKSKMSLELR-PTAPSDQGRLNEAFQDED--LEEQNAPGNSTVRSRVVQSGEQGRAKQDDRQITIEQEPLGPKEGTEEESEDERQKGFLERKYDTVCEFCRKHRVILQHTIWAVLLTGFLALVIAACALNFHRALPLFVITLVTIFFVVWDRLMAKYEQRIDDVLSPGKRLLERHWFWLKWVVWCSLILAVILWLALDTARLGQQQLISFGGLVMYIVLLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGKQVQTFLGYTDAGAQFVFGEKYT-DHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFVGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKNAMKMENGDSRNLLEAATQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFDYPQLSFELICSYIFMPFSFMMGVDWQDRFMVAKLIGYKTFFNEFVAYEHLSKFINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGMLSDTPVAINCHHVLE---SSKVLSNTTEVASCCQGLFNSTVARGPNDVLPGGNFSLYTLKSCCNLLKPPTLNCGWIPNIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERH8-1", "uniprot_id": "S28A3_MOUSE", "id": "Q9ERH8-1", "name": "Solute carrier family 28 member 3", "aln": "MSRADP--GKNSEPSESKMSLELR-PTAPSDLGRSNEAFQDED--LERQNTPGNSTVRNRVVQSGEQGHAKQDDRQITIEQEPLGNKEDPEDDSEDEHQKGFLERKYDTICEFCRKHRVVLRSTIWAVLLTGFLALVIAACAINFHRALPLFVITLVTIFFVIWDHLMAKYEQRIDDFLSPGRRLLDRHWFWLKWVVWSSLILAIILWLSLDTAKLGQQNLVSFGGLIMYLILLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGRQVQTFLGYTDTGARFVFGEKYT-DHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFIGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKSAMKMENGDSRNLLEAASQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFNYPELSFELICSYIFMPFSFMMGVDWQDSFMVAKLIGYKTFFNEFVAYDHLSKLINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGILSDTPVDINCHHVLE---NGRVLSNTTEVVSCCQNLFNSTVAKGPNDVVPGGNFSLYALKSCCNLLKPPTLNCNWIPNKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAS3-1", "uniprot_id": "S28A3_HUMAN", "id": "Q9HAS3-1", "name": "Solute carrier family 28 member 3", "aln": "--------------------MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQSREHTNTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYK-DHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTFNCNGISNTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7N3-1", "uniprot_id": "A1Z7N3_DROME", "id": "A1Z7N3-1", "name": "", "aln": "----------------MAEPIEGEQEEKPPPSRAKRITYLVLHVLLHIIFISYFTAATIIFIFYDKDSKECWPNRGSEATTESIDNSTEDDDDDDYDTEETSEKPVPEVKPKLLCQINWCHGYGFLIVLFILFYILWLYYWVFKPFVGIKLYNN---------------YLEPVIDKWIAFSR-------QWIVSGVMLAIVLAVVVAYLGFECRNDAYKAIGLLGPVCFVLIGFAVSKHHLQVPWRIVTHGLLGQLLLGILCLRLPFGRSIFQCLGDKVTIFLNYAQHGARFVYGDRICDEYVFAFAILAVVFFFSVITSIMYYLGWMQFILNGFGFLLQAMVGTTVCESVNAAGNVFLSMTESPLVIRPYIEILTVSELHAICTSGYATVAGTVLGAYVSFGASASFLIAASVMAAPGSLAFAKLFYPETEES-LTRSDNIKLESSTDTSILDAAASGAAAALLIVLGIVSNIIAFLAIVFFLDAVTEWIFELIGLHNITLLYILSQIFIPIVFVMGVPWHDCQAIGLVVAQKSFINEFVAYRNLGILVSDKK-------------VDPRSAAIATFALCGFANPGSLGIVIASLSAMAPSRRSDITRVAFRSYFAGSFVSFTSASLAGILIQN-------------------------------------------EYTGGN---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . * . : . *. . .: : :. . :. :. :::.: :: : :. : : . : :*: : : : .:: . .: *: * **. :: .: *: : :::**::. .: . : :.: * : :::: * .**: :* ** * *: *:***:* ** * *: :* :* ** *:: ** **:*:: ::.*** :*.:*.***.: *::**** **:*:. .*::: . *:: *** *:**:*:. *****:::**: :* ****:* *:*::*:**:*****:***..::.*::****:**.:** ****:****:. :* .. :*:*.. . .:*:**:.**:::: :* .*. *:*****:: *:::. .*: .::. :::: * * **:*: *:*** *:* :. ::. *:*:****** :*. : :* :. ** ***:******* *******..*:::****: **: *.*: :**:...* :*.:**:* .. .*** ", "identical_positions": 184, "similar_positions": 208, "identity": "25.84%" }, { "cls_id": "homologset.agr.MGI:2137379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFT4-1", "uniprot_id": "A0ABK0LFT4_RAT", "id": "A0ABK0LFT4-1", "name": "Mediator of RNA polymerase II transcription subunit 15", "aln": "MDVSGQETDWRSAAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPTPGAAGIGMPPRGPGQSLGGMGGLGAMGQPLPLSGQPPPGTSGMAPHGMAVVSTATPQTQLQLQQVALQQ--QQQQQQQQ-FQQQQAALQQQQQQQQQQQQQQQFQAQQNAMQQQFQAVVQQQQ--LQQQQQQQHLIKLHHQSQQQQMQQQQQLQRMAQLQLQQQQQQQQQQQ-----ALQAQPPMQQPPMQQPQPPPSQALPQQLSQMHHPQHHQPPPQAQQSPVAQNQPPQLQPQSQNQPLVS---------QAQALSGPMLYAAQQPLKFVRPPMVVQQP-------QVQPQVQP-QAAVQTAQSAQMVAPGVQMIAEA----------LAQGGMHVRARFPPTSTMSAGPSSSISLGGQPTAQVSQSSLTMLSSPSPGQQVQTPQSMPPPPQPSPQPG---SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQN--FSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVLPTKQQDLCQPLLDAVLANIRSPVFNHSLYRTFVPAMMAIHGPPIVSPVVCSRKRRFEEDE--RQSIPNVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPPLELSVPADYPAQSPMWVDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSIHQACLSAA--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924H2-1", "uniprot_id": "MED15_MOUSE", "id": "Q924H2-1", "name": "Mediator of RNA polymerase II transcription subunit 15", "aln": "MDVSGQETDWRSAAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPTPGAAGIGMPPRGPGQSLGGMGGLGAMGQPLPLSGQPPPGTSGMAPHGMAVVSTATPQTQLQLQQVALQQ--QQQQQQQQQFQQQQAALQQQQQQQQQQQQQQQFQAQQNAMQQQFQAVVQQQQ--LQQQQQQQHLIKLHHQSQQQQIQQQQ-LQRMAQLQLQQQQQQQQQQ------ALQAQPPMQQPSMQQPQPPPSQALPQQLSQLHHPQHHQPPPQAQQSPIAQNQPPQIPPQSQSQPLVS---------QAQALPGPMLYAAQQQLKFVRAPMVVQQPQVQPQVQQVQPQVQP-QAAVQAAQSAQMVAPGVQMIAEA----------LAQGGMHVRARFPPTSTMSAGPSSSISLGGQPTTQVSQSSLTMLSSPSPGQQVQTPQSMPPPPQPSPQPG---SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQN--FSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVLPTKQQDLCQPLLDAVLANIRSPVFNHSLYRTFVPAMMAIHGPPIVSPVVCSRKRRFEEDE--RQSIPNVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPPLELSVPADYPAQSPMWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSIHQACLSAA--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RN5-1", "uniprot_id": "MED15_HUMAN", "id": "Q96RN5-1", "name": "Mediator of RNA polymerase II transcription subunit 15", "aln": "MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQ--QQQQQQFQ--QQQQAALQQQQQQQQQQQ----FQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS---------QAQALPGQMLYT-QPPLKFVRAPMVVQQP-------PVQPQVQQQQTAVQTAQAAQMVAPGVQMITEA----------LAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQN--FSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVCTRKRRLEDDE--RQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSVHQACLSAA--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVN7-1", "uniprot_id": "MED15_DANRE", "id": "Q7ZVN7-1", "name": "Mediator of RNA polymerase II transcription subunit 15", "aln": "MDVPGPDSDWRSPAFRQKVVAQIEEAMRKAGTGHTKSSTEMESHVFTKAKTREEYLSMVARLIIHFRDIHKKAQGG--PDPINALQNLPGG-VPGVIG----PRPPGAQMGGMGQMSMGPHAMQGVAGGQQGAGAAGPMQQMIQQQQQQQQQQQQQQSIQFQTFQPQQQQQATMQSQQPSAMFQQIRLQQLQQHHQNQQMQHQNQQQQQAQNQQQQNQLHQTRMQQQLQLQQLQQQQQQQLHQQQVHAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ-AQAQAQSIQQMQQQQQLQVQAQGQPQVQGQGGAVQMPPHSQQQQVLVPQMVQGQHSQMSALSQQQQLKLQQAMQARMQQQQQQQQQ-QQQQQQQQQQQQQQQQQQQQQQQQQHQQQQVQQVQQASQLTAVPGQMMPRPGMQIPPRLPRATPNSAIPQNPVAIGGQQMPQAQQ----MMSSPSP-VQVQTPQSMPPPPQPQPSPQPPSSQPNS-VSSGPTPSPGGFQPSPSPQPSQSPASSRTPQSYPLQVPSPGPLNTPGNPSSVMSPAGASQSEDQLYMDKLRQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLNILTDPNTRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPCTKKQYLCQPILDAVLANIRSPVFNHSLYRTFAPAMTAIHGPQITGPSIPSRKRKLEDDE--RQAIPNILQGEVARLNSKFLVNLDPSFCSNNGMVHLICKLDDKNLPSVPPLQLSIPADYPDQSPHWEDDGQQYEANPFLRTVHKNMTSKLLQLPDKHSVTALLNTWAQSVRQACLSA---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y149-1", "uniprot_id": "MED15_DROME", "id": "Q9Y149-1", "name": "Mediator of RNA polymerase II transcription subunit 15", "aln": "-----MTEDWQSQKFRQNVISKIHDLLPPNAQDQTKNAGVMENHIFRKSRTKDEYLGLVAKLFMHYKDMSRKSQQQQQQQQQQGGP-PPNAEMGGGQNMMQDPLNALQNLASQGNRNPQMMPMGAGGGAPVPGGPGTASNLLQSLNQQRPGQQQMQPMSNIR---GQMPMGAGGAGAQQMMQVQQMQQGGNAPGVMNVMGAGGGQNQGQIVGNPGQQMGVGVGMPNQMVGPGPNSGPAVG--------------------------------GAGGPNAAPGAGGPGPNQMQGGPMNVNAMQQMPPMQQIQQNQLG-MGMNPMMRMG-------------------QGNGMGGPQGMPGQGMQGMPQGPHNVVGGP------AGQQQVGGAGLPPNAVQQGGMNPMGGMGVNMP-------------PNLQQKPNMPMGQAGQMFPGNRGGVG-VGGQQPGQPFMRSSPSPADAQQLQQQAQLQQMQQQQQQLVVGNQTPTQQPPTPQMPTPN-MIPSPALVPQSSPQMMQMQNS-QRNIRQQSPSASINTPGQVTGNSPFNPQEEALYREKYKQLTKYIEPLKRMLAKISNDGTNVEKMTKMSKLLEILCNPTQRVPLETLLKCEKALEKMD---------LISYSGQQFGKSSNPLLEVINTTLQSPVANHTLYRTFRPTLELLFGTDITAPVPAKRPRVEEKSTSFEQEVPHVLQGEIARLDTKFKVKLDTTSQINNKAIRLICCLDDKRLPSVPPVSVSVPEEYPWQAPDCSLAEQEYSATPFLQTVQQALIARISKLPKNYSLSHLLDTWEMAVRQACSPQSKPRAVCELSTLLGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:* ***:::::*.: : . ::*.: **.*:* *::*::***.:**:*::*::*: .* . : :. ... * . * . .:.. * . .: . . . * * * : * * ** : *:* * : * ::: :. * . . *. . .:. ::: * * * . . :: * ..: * * * : * : . .:: ..:* . . * . :* * * .**: *:* .: * . . . *.. .: *:*. : ***: *..** : :. .: . .* : .*..* . : . *: * :* :**:******:**: **.:: . :.::**..**:** :*. * **:** *** ****:. . : .:*:*:.: :.::*** **:***** *:: :.*. *..* .* * *.. .* :* :****:***:.** *:**.: ** ::*** **** ******:.:*:* :** *:* :*.*.***::*:: : ::: :**.::*:: **:** :::*** . ", "identical_positions": 173, "similar_positions": 203, "identity": "20.57%" }, { "cls_id": "homologset.agr.MGI:2137383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT92-1", "uniprot_id": "E9PT92_RAT", "id": "E9PT92-1", "name": "", "aln": "MTAWRKFKSLLLPLVLAVLCAGLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSLLTLWFTTDFAVSAQGFKAMYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLSGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSASISSPHFPSEYDNNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDSSHKNSVLTQGGVSLVSDMCPDPGIPDNGRRAGSDFRVGANVQFSCEDNYVLQGAKGITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECQAAFELVGERVITCQRNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPAQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPVNGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLNCEWVIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPTSSSPLIGEYHGTQAPQFLISTGNYMYLLFTTDSSRASVGFLIHYESVTLESDSCLDPGIPVNGHRHGSNFGIRSTVTFSCDPGYTLSDDDPLICEKNHQWNHALPSCDALCGGYIHGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMNFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFAEYDLEPCDDPGVPAYSRRIGFQFGVGDTLAFTCFQGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRARTFQLFEGDTLKVYDGKDSSSRSLGVFTRSELMGLVLNSTSNHLRLEFNSNGSDTAQGFQLTYTSFDLVKCEDPGIPNYGYRIRDDGHFTDTVVLYSCNPGYAMHGSSTLTCLSGDRRVWDKPMPSCVAECGGLVHAATSGRILSPGYPAPYDNNLHCTWTIEADPGKTISLHFIVFDTETAHDILKVWDGPVDSNILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIASTCNDPGMPQNGTRYGDSREPGDTITFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPSCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRIKVNPDFVIALIFKSFSMEPSYDFLHIYEGEDSNSPLIGSFQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRIGTDFKLGSTVTYQCDSGYKIVDPSSIECVTGADGKPSWDRALPACQAPCGGQYVGSEGVVLSPNYPHNYTAGQICIYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHPQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTAIRCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCVWKIIVSEGSGIQIQVISFATEQNWDSLEIHDGGDMTAPRLGSFSGTTVPALLNSTSNQLCLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNGIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLTSMSGVILSPGFPGSYPNNLDCTWKISLPIGYGAHIQFLNFSTEANHDYLEIQNGPYHSSPMMGQFSGPDLPASLLSTTHETLIRFYSDHSQNRQGFKLSYQAYELQNCPDPPAFQNGFMINSDYSVGQSISFECYPGYILLGHPVLTCQHGTDRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCLWLVTVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKRCPPPPVVPQADLLTEDEDFEIGDFVKYQCHPGYTLLGSDTLTCKLSSQLLFQGFPPTCEAQCPANEVRTESSGVILSPGYPGNYFNSQTCAWSIKVEPNFNITLFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNHLYLRWSTDHATSKKGFKIRYAAPYCSLTSTLKNGGVLNKTAGALGSKVQYFCKPGYRMIGHSNATCRRNPVGVYQWDSMAPLCQAVSCGIPEAPGNGSFTGNEFTLDSKVTYECNEGFKLDASQQATAVCQEDGLWSNRGKPPTCKPVPCPSIEGQLSEHVLWRLVSGSLNEYGAQVLLSCSPGYFLQGQRLLQCQANGTWNTEEDRPRCKVISCGSLSFPPNGNKIGTLTMYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGLTNGSEFNLNDLVNFTCHTGYLLQGASRAQCRSNGQWSSPLPICRVVNCSDPGFVENAVRHGQQNFPESFEYGTSVMYHCKKGFYLLGSSALTCMASGLWDRSLPKCLAISCGHPGVPANAVLTGELFTFGATVQYSCKGGQILTGNSTRVCQEDSHWSGSLPHCSGNSPGFCGDPGTPAHGSRLGDEFKTKSLLRFSCEMGHQLRGSAERTCLVNGSWSGVQPVCEAVSCGNPGTPTNGMILSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLPNGIQFGTDFTFNKTVSYQCNPGYLMEPPTSPTIRCTKDGTWNQTRPLCKAVLCSQPPSVPNGKVEGSDFRWGASISYSCVDGYQLSHSAILSCEGRGVWKGEVPQCLPVFCGDPGTPAEGRLSGKSFTFKSEVFIQCKPPFVLVGSSRRTCQADGMWSGIQPTCIDPAHTACPDPGTPHFGIQNSSKGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPAFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFINSVWKGYYEYLGKRQPATLTVDWFNATSSKVNATFTAASQVQLELTGVYKKEEAHLLLKAFHIKGPADIFVSKFENDNWGLDGYVSSGLERGGFSFQGDIHGKDFGKFKLERQDPSNSDADSSNHYQGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923L3-1", "uniprot_id": "CSMD1_MOUSE", "id": "Q923L3-1", "name": "CUB and sushi domain-containing protein 1", "aln": "MTAWRKFKSLLLPLVLAVLCAGLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSLLTLWFTTDFAVSAQGFKAMYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLSGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSGSISSPHFPSEYDNNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDSSHKNSVLTQGGVSLISDMCPDPGIPDNGRRAGSDFRVGANVQFSCEDNYVLQGAKGITCQRVTETLAAWNDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECQAAFELVGERVITCQKNNQWSGNKPSCVFSCFFNFTAPSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPAQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPVNGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLNCEWVIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPTSSSPLIGEYHGTQAPQFLISTGNYMYLLFTTDSSRASVGFLIHYESVTLESDSCLDPGIPVNGQRHGSNFGIRSTVTFSCDPGYTLSDDEPLVCEKNHQWNHALPSCDALCGGYIHGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMNFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFAEYDLEPCDDPGVPAFSRRIGFQFGVGDTLAFTCFQGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSHYDNNHECIYKIETEAGKGIHLRARTFQLFEGDTLKVYDGKDSSSRSLGVFTRSEFMGLVLNSTSNHLRLEFNTNGSDTAQGFQLTYTSFDLVKCEDPGIPNYGYRIRDDGHFTDTVVLYSCNPGYAMHGSSTLTCLSGDRRVWDKPMPSCVAECGGLVHAATSGRILSPGYPAPYDNNLHCTWTIEADPGKTISLHFIVFDTETAHDILKVWDGPVDSNILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIASTCNDPGMPQNGTRYGDSREPGDTITFQCDPGYQLQGPAKITCVQLNNRFFWQPDPPSCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRIKVNPDFVIALIFKSFSMEPSYDFLHIYEGEDSNSPLIGSFQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRIGTDFKLGSTVTYQCDSGYKIVDPSSIECVTGADGKPSWDRALPACQAPCGGQYTGSEGVVLSPNYPHNYTAGQMCIYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHPQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTAIRCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCVWKIIVSEGSGIQIQVISFATEQNWDSLEIHDGGDMTAPRLGSFSGTTVPALLNSTSNQLCLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNGIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLTSMSGVILSPGFPGSYPNNLDCTWKISLPIGYGAHIQFLNFSTEANHDYLEIQNGPYHSSPMMGQFSGPDLPTSLLSTTHETLIRFYSDHSQNRQGFKLSYQAYELQNCPDPPAFQNGFMINSDYSVGQSISFECYPGYILLGHPVLTCQHGTDRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCLWLVTVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKRCPPPPAVPQADLLTEDEDFEIGDFVKYQCHPGYTLLGSDTLTCKLSSQLLFQGSPPTCEAQCPANEVRTESSGVILSPGYPGNYFNSQTCAWSIKVEPNFNITLFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNHLYLRWSTDHATSKKGFKIRYAAPYCSLTSTLRNGGILNKTAGAVGSKVHYFCKPGYRMIGHSNATCRRNPVGVYQWDSMAPLCQAVSCGIPEAPGNGSFTGNEFTLDSKVTYECNEGFKLDASQEATTVCQEDGLWSNRGKPPTCKPVPCPSIEGQLSEHVLWRLVSGSLNEYGAQVLLSCSPGYFLQGQRLLQCQANGTWSTEEDRPRCKVISCGSLSFPPNGNKIGTLTIYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGLTNGTEFNLNDLVNFTCHTGYRLQGASRAQCRSNGQWSSPLPICRVVNCSDPGSVENAVRHGQQNFPESFEYGTSVMYHCKTGFYLLGSSALTCMASGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGATVQYSCKGGQILTGNSTRVCQEDSHWSGSLPHCSGNSPGFCGDPGTPAHGSRLGDEFKTKSLLRFSCEMGHQLRGSAERTCLVNGSWSGVQPVCEAVSCGNPGTPTNGMILSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLPNGIQFGTDFTFNKTVSYQCNPGYLMEPPTSPTIRCTKDGTWNQSRPLCKAVLCNQPPPVPNGKVEGSDFRWGASISYSCVDGYQLSHSAILSCEGRGVWKGEVPQCLPVFCGDPGTPAEGRLSGKSFTFKSEVFIQCKPPFVLVGSSRRTCQADGIWSGIQPTCIDPAHTACPDPGTPHFGIQNSSKGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPAFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFINSVWKGYYEYLGKRQPATLTVDWFNATSSKVNATFTAASRVQLELTGVYKKEEAHLLLKAFHIKGPADIFVSKFENDNWGLDGYVSSGLERGGFSFQGDIHGKDFGKFKLERQDPSNSDADSSNHYQGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PZ7-1", "uniprot_id": "CSMD1_HUMAN", "id": "Q96PZ7-1", "name": "CUB and sushi domain-containing protein 1", "aln": "MTAWRRFQSLLLLLGLLVLCARLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWKGYYEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGLDGYVSSGLERGGFTFQGDIHGKDFGKFKLERQDPLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTVV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*:**** * * **** **********************************************************************************************:******************:************************************.*******************************************.***********:****************************************************************************************************.*******:****:*:**********:***************************:*.*************.********************************************************************************************************************************************************* **************:*********************.*********************************************************************:******************************************:******************************************************************************:***:*******************************:***********************:********.**:*:*************************:***.:********************:**:**:*******************:*********************************** ******************************************************************:**************:******:*****:*:*:** *************************************************:**********************:*:********************.**.**:.*::**:******** ****:***** *****************************:*********************.***************:***:***** :************************* ******************* **************:**********************************************:*******************.***:************ *******************:**********************************:***************.***********************:******************************************************:*********:**********:***** ** *********:.**:*:*******.*******************:*:*********************************.********************************************************************************************::************************************************:*****:****************************:************************ **********************************.******************************************************:::.********************:***********************:*********:***:*****.***::**********:**************:*************.****:***********:**********:********** :****************************************:**:********************************************************************************:* ***.****::****:******************:*:* ********* *:* ************** ********************:********:***:*********************************************:**************************** .*:***:**:****:****:*********:***********:*:*****::************:*****************.***:*****::**:**:**********:*********.*****.******:***********************:*:* ***:*******. ::** *:********************:************************************************************************************************************:***:******:*****:*** ***.**************** ********** ****:************** *::****.**************.********************************:**.*:***:*.: * **.************:****:**.******************:********************.*****:******:********************:*****************************************************.***********************:**. **.******** ** ::*:****** ***.* **.*********:******:**********************:************ ************:*****:***.**:*******.***** *************.:***************:*************************************************************:************************************************************:**:********************************: ** *:*:***:*************:*** ****************************:******************** *.* ***.**:***********************************************************************************", "identical_positions": 3319, "similar_positions": 199, "identity": "93.13%" }, { "cls_id": "homologset.agr.MGI:2137384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES02-1", "uniprot_id": "MEPE_RAT", "id": "Q9ES02-1", "name": "Matrix extracellular phosphoglycoprotein", "aln": "--------MQAVSVGLFLFSMTWAAP----------------------------------KLNEDGSSG-----------------------------------------GNQGNIH---LASVKPEPMVGKGTEGGRDAPLHLLDQNRQGATLLRNITQPVKSLVTGTEVQSDRNKEKKPQSVLSVIPTDVHNTNDYSEDTENQQRDLLLQNSPGQS---KHTPRARRSTHYLTHLPQIRKILSDFEDSASPDLLVRGDNDVPPFSGDGQHFMHTPDRGGAVGSDPESSAGHP-VSGSSNVEIVDPHTNGLGSNEIPGREGHIGGAYATRGKTAQGAGSADVSLVEGSNEITGSTKFRELPGKEGNRVDASSQNAHQGKVEFHYPQAPSKEKVKGGSREHTGKAGYNEIPKSSKGGASKDAEESKGNQVTLTESQRFPGKGKGQ----SSHSLGNEVKSEEDSSNSLSRE-------GIAIAHRRTSHPTRNRGMSQRRGSWASRRPHPHRRVSTRQRD-SSESSSSGSSSESSGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4L6-1", "uniprot_id": "MEPE_MOUSE", "id": "Q8K4L6-1", "name": "Matrix extracellular phosphoglycoprotein", "aln": "MTPEGLMKMQAVSVGLLLFSMTWAAP----------------------------------MPNEDRSSC-----------------------------------------GNQDSIHKDLAASVYPDPTVDEGTEDGQGALLHPPGQDRYGAALLRNITQPVKSLVTGAELRREGNQEKRPQSVLSVIPADVNDAKVSLKDIKNQESYLLTQSSPVKSKHTKHTRQTRRSTHYLTHLPQIKKTPSDLEGSGSPDLLVRGDNDVPPFSGDGQHFMHIPGKGG-AGSGPESSTSRP-LSGSSKAEVIDPHMSGLGSNEIPGREGHGGSAYATRDKAAQGAGSAGGSLVGGSNEITGSTNFRELPGKEGNRINAGSQNAHQGKVEFHYPQVASREKVKGG-VEHAGRAGYNEIPKSSKGSSSKDAEESKGNQLTLTASQRFPGKGKSQGPALPSHSLSNEVKSEEN-----------------HYVFHGQNNLTPNKGMSQRRGSWPSRRPNSHRRASTRQRD-SSESSSSGSSSESHGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ76-1", "uniprot_id": "MEPE_HUMAN", "id": "Q9NQ76-1", "name": "Matrix extracellular phosphoglycoprotein", "aln": "--------MRVFCVGLLLFSVTWAAPTFQPQTEKTKQSCVEEQRQEEKNKDNIGFHHLGKRINQELSSKENIVQERKKDLSLSEASENKGSSKSQNYFTNRQRLNKEYSISNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTAIKLLGEENKENTPRNVLNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKS---KSTHRIQHNIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFSGDGQPFKDIPGKGEATGPDLEGKDIQTGFAGPSEAESTHLDTKKPGYNEIPEREENGGNTIGTRDETAKEADAVDVSLVEGSNDIMGSTNFKELPGREGNRVDAGSQNAHQGKVEFHYPPAPSKEKRKEGSSDAAESTNYNEIPKNGKGSTRKGVDHSNRNQATLNEKQRFPSKGKSQGLPIPSRGLDNEIKNEMDSFNGPSHENIITHGRKYHYVPHRQNNSTRNKGMPQGKGSWG-RQPHSNRRFSSRRRDDSSESSDSGSSSESDGD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:...***:***:***** *:: ** .*: . * *: *.. .:* *.* .* : .*:. **:*:** * : . **. :: : *:*: *:.**.:**:.:: :: :* :: : *.** :* * * : ::. .**.**.:::* **:*.*. .** *****:.******* * . *.:* .*.. *.. :. .:*.*:.* . . . * **** ** : *.: .**.::*: *.:.. *** ***:* ***:*:****:****::*.************** ..*:** * * : : :.******..**.: *..:.*: ** **. .****.***.* .*:.*.**:*.* : . : .: * *:**.* :*** *:*:.:** *:*:** *****.******* **", "identical_positions": 186, "similar_positions": 142, "identity": "34.64%" }, { "cls_id": "homologset.agr.MGI:2137410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFN5-1", "uniprot_id": "A0ABK0LFN5_RAT", "id": "A0ABK0LFN5-1", "name": "Twinkle mtDNA helicase", "aln": "----------------------------MWLLLRRAYPLR------ILLPLRGEWMGRRGLPRSLAPGPPRRRYRKEALPALEVPVSPVTTTEIRQYLRAHGIPFQDGHSCLRAPSPFVAPSD--IKNQKKDATTSFCLFIDKTTGHFLCMTSLAEGSWEDLQASVEGRGD----GAKEGILLGEGPEAEDREE-------VLRIWNRAIPLWELPDPQETQLARVMFGLTKVTDDTLRRFNVRYLRSTRSLVFPWFTPGSSGLRGLKLLGVEGQENG-VQYVETTIPRPGVYHNLFGLPLIGRRDTEVVLTSRELDSLALSQSTGLPTLSLPRGTVCLPPALLPYLEQFRRIVFWLG-DDLRSWEAAKLFARKLNPKRCSLVRPGNQQPRPLEALNQGLSLPRILRTALPAWHKSIVSFRQLREEVLGELSNVDQAAGVRWSRFPDLNRLLKGHRKGELTVFTGPTGSGKTTFISEYALDLCTQGVNTLWGSFEISNVRLARVMLTQFAVTRLEEQLDKYEEWADRFEDLPLYFMTFHGQQSIRSVIDTMQHAVYVYDVCHVVIDNLQFMMGHEQLSTDRIAAQDYIVGAFRKFATDNSCHVTLVIHPRKEDDDKELQTASIFGSAKASQEADNVLILQDRKLVTGPGKRYLQVSKNRFDGDVGVFPLEFNKSSLTFSIPPKSKARLKKIKDDNGLVAKKSSSGKKGSAHQNSETCIGQDP--CQPDTSPSSRHKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIW5-1", "uniprot_id": "PEO1_MOUSE", "id": "Q8CIW5-1", "name": "Twinkle mtDNA helicase", "aln": "----------------------------MWLLLRRAYPLR------ILLPLRGEWVGRRGLPRSLAPGPPRRRYRKEALPALEMPVSPVTTTEIRQYLRAHGIPFQDGHSCLRAPSPFVVSSD--IKNEKKDAPTSFCLFIDKTTGHFLCMTSLAEGSWEDLQASVEGRGD----GAKEGVLLREGPEAEVREE-------VLRIWNRAIPLWELPDPEEAQLARVMFGLTKVTDDTLRRFSVRYLRSARSLVFPWFTPGSSGLRGLKLLGAEGQENG-VQYVETTIPRPGVYHNLFGLPLISRRDTEVVVTSRELDSLALSQSTGLPTLSLPRGTVCLPPALLPYLEQFRRIVFWLG-DDLRSWEAAKLFARKLNPKRCSLVRPGNQQPRPLEALNQGLSLPRILRTALPAWHKSIVSFRQLREEVLGELSNVEQAAGVRWSRFPDLNRLLKGHRKGELTVFTGPTGSGKTTFISEYALDLCTQGVNTLWGSFEISNVRLARVMLTQFAVTRLEEQLDKYEEWADRFEDLPLYFMTFHGQQSIRSVIDTMQHAVYVYDVCHVVIDNLQFMMGHEQLSSDRIAAQDYIVGAFRKFATDNSCHVTLVIHPRKEDDDKELQTASIFGSAKASQEADNVLILQDRKLVTGPGKRYLQVSKNRFDGDVGVFPLEFNKNSLTFSIPPKSKARLKKIKDDNGLVAKKSSSGKKGAAHQNPEICLGQDPSPAQPDTSKSSG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RR1-1", "uniprot_id": "PEO1_HUMAN", "id": "Q96RR1-1", "name": "Twinkle mtDNA helicase", "aln": "----------------------------MWVLLRSGYPLR------ILLPLRGEWMGRRGLPRNLAPGPPRRRYRKETLQALDMPVLPVTATEIRQYLRGHGIPFQDGHSCLRALSPFAESSQ--LKGQTG-VTTSFSLFIDKTTGHFLCMTSLAEGSWEDFQASVEGRGD----GAREGFLLSKAPEFEDSEE-------VRRIWNRAIPLWELPDQEEVQLADTMFGLTKVTDDTLKRFSVRYLRPARSLVFPWFSPGGSGLRGLKLLEAKCQGDG-VSYEETTIPRPSAYHNLFGLPLISRRDAEVVLTSRELDSLALNQSTGLPTLTLPRGTTCLPPALLPYLEQFRRIVFWLG-DDLRSWEAAKLFARKLNPKRCFLVRPGDQQPRPLEALNGGFNLSRILRTALPAWHKSIVSFRQLREEVLGELSNVEQAAGLRWSRFPDLNRILKGHRKGELTVFTGPTGSGKTTFISEYALDLCSQGVNTLWGSFEISNVRLARVMLTQFAEGRLEDQLDKYDHWADRFEDLPLYFMTFHGQQSIRTVIDTMQHAVYVYDICHVIIDNLQFMMGHEQLSTDRIAAQDYIIGVFRKFATDNNCHVTLVIHPRKEDDDKELQTASIFGSAKASQEADNVLILQDRKLVTGPGKRYLQVSKNRFDGDVGVFPLEFNKNSLTFSIPPKNKARLKKIKDDTGPVAKKPSSGKKGATTQNSEICSGQAPTPDQPDTSKRSK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ICC1-1", "uniprot_id": "A0A0R4ICC1_DANRE", "id": "A0A0R4ICC1-1", "name": "Twinkle mtDNA helicase", "aln": "MWRSRFLRSAGCLLQATVCSPHKLSHLPQWRFLSSHQPLLNPVLQRYLRPPSSTWYCPKSHINPTVALYFCRTLRKDAKSVIDFDQ-PLTVTDIKQYLRFKEIPFHDGHSCLHAPSIFTAP------LPEGSGRENFSLFIDKTTGQFLCKDTLVEGNWEDFQDCLEVMLNEGQTSISPNVLLGFPESLEEQEERGMEVKEVQRIWSSSVPFSDLMED-EVQLIKAMFQIAKLTNATLKKFGVRFFKPTKSLVFPWFGGRDSGLRGVKLLSASTRDDGRVVYTEATVPKVSSYHNLFGLPLVGRKDAEVVLTGREVDSMAVSQATGLPSLALPRGVSCLPPILLPYLEQFKKVTLWLG-GDMRSWEASKIFSRKLGLKRCSLVRPGEFQPCPSEALAQGRNLTRIVKASIPAAHKSIVSFKQLREDVYGELANVEQVAGIQWSRFPELNRILKGHRKGELTVFTGPTGSGKTTFISECALDLCMQGVNTLWGSFEINNVRLAKIMLTQFSKQRLEENLDQYDMWADKFEDLPLYFMTFHGQQNIKTVLDTMQHAVYVYDISHVIIDNLQFMMGQENLSVDKFAVQDHIIGIFRKFATNSCCHVTLIIHPRKEEDDKELQTASIFGTAKASQEADNVLILQEKKLVTCPGRRSLQVAKNRFDGDVGVFPLEFNKASLTFSAPVKGKQKLRKVKVDVNENTEETEEAELKEMSEKPLKAAKTKSSKTVKGSTAAKSTAD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL76-1", "uniprot_id": "PEO1_DROME", "id": "Q9VL76-1", "name": "Mitochondrial DNA helicase", "aln": "-----------------------------MRRAGLIKPLLR-------INNEKQRVWRKNYATQVVSG------------LEECSLDPKEYVDFKRQLRQLNLPHKDGHTCLQLECRLCDRNRQPVTNAQKGTDHGLLAYVNKRTGAFICPN-------CDVKTSLT--------SALLSYQLPKPVGYKQPLQ-------RQPVYESRFPHLAVVTP----EACAALGIKGLKEDQLNAIGAQWE-PQQQLLHFKLRNAAQVEVGEKVLYLGDRREE--------IFQSSSSSGLLIHGAMNKTKAVLVSNLIDFIVLATQNIETHCVVCLPYELKTLPQECLPALERFKELIFWLHYDASHSWDAARAFALKLDERRCLLIRPTETEPAPHLALRRRLNLRHILAKATPVQHKAITTFGAMRNDILSELQNIEKVNGVKWKRFPVLNKLLKGHRRGELTILTGPTGSGKTTFMSEYSLDLAMQGVNTLWGSFEIRNTRLAATLLRQYVGYPLDDRLHEFNHWAAEFERLPLYFMTFHGQQPLKPVLEAIEHASYVHDVMHVIIDNLQFMMGVSTFRGDKFFEQDSIIAAFRSFATKHNVHVTLVMHPRKERQEDELTTSSVFGTAKATQEADNVLIIQDKRLTSVRGKKYLQIAKNRYSGDLGIMPLEFDKDGLSYSTQIQNAKRKREKTPSEN-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :. .. : * .:::: ** :*.:***:**: . : .: :::* ** *:* *.: .: . . * : : ::. .* : . : : :.: *. :..:: . :.*:. : . * *:* : : : : . .*: :.: .: :* . :. :* .: : ** ** ** **:*:.: :** . :**:*:: *: **. :** *:** : :* * ** .* :*: : *. **:*.:* :*::: .** *:::. *::*.*** **::*****:****::***********:** :***. ************ *.*** :* *: *::.*.::: ** .** ************ ::.*:::::** **:*: **:********* . : *:: ** *:. **.***. ****::***** ::.** *:*:**:***:********:*:::*.: *:: **::***:.**:*::****:* .*::* :. : :: . . . ", "identical_positions": 202, "similar_positions": 186, "identity": "27.41%" }, { "cls_id": "homologset.agr.MGI:2137414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI63-1", "uniprot_id": "KIFC1_RAT", "id": "Q5XI63-1", "name": "Kinesin-like protein KIFC1", "aln": "-----------MRGRGSRDTGTQSAAFASRPVRTTVDMQAQRAPLMEVKRNLELSTTLVKSSSRLPLP---------------GSRLKRGPDQMEDGLEPAKKRTRGMGTVTKVD-----TSRPRGPPLSAVS-----TAAQKGPRKTGPRGCSAVGPVLRNQKPAPAAPAQKPGTSTAPAVAG-KKPGKRPAWDLKGQLCDLHEELKQYREKTQTLDRENQGLREQLREVQEQATTLGTERNTLEEELASVRRRAEQSQ----------------------QKLETLGARVL-ELEECLGTKERLVQELQTERLQLQEERSTLSTQLEEREREFQASEAALSSSRAEVLCLRQKTAAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTRLCLSRSDDRRSTLTRAPAAATRHDFSFDRVFPPGSKQEEVFEEISMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGDCEIR---RAGPGSEELTVTNARYVPVSCEKEVEALLHLAQQNRAVARTAQNERSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLTLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PUA5-1", "uniprot_id": "E9PUA5_MOUSE", "id": "E9PUA5-1", "name": "Kinesin-like protein", "aln": "-----------------------------------MDVQAQRK-GREGKRNVELKAALVKSSSRLPLS---------------ASSLKRGPDQMEDALEPAKKRTRVMGAVTKVD-----TSRPRGPLLSTVSQTQGHNAAQKGPKKTGPGGCSAVGTVLRSQKPAPAAPA-KPGTSTAPVVVG-KRAGKRPAWDLKGQLCDLNEELKRYREKTETLELENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQ----------------------QRLETLSARVL-ELEECLGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQKTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDRPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLAGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIR---RASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLPLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BW19-1", "uniprot_id": "KIFC1_HUMAN", "id": "Q9BW19-1", "name": "Kinesin-like protein KIFC1", "aln": "-------------------------------------MDPQRSPLLEVKGNIELKRPLIKAPSQLPLS---------------GSRLKRRPDQMEDGLEPEKKRTRGLGATTKIT-----TSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQ----------------------QELKNLRACVL-ELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIR---RAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUU7-1", "uniprot_id": "Q1LUU7_DANRE", "id": "Q1LUU7-1", "name": "Kinesin-like protein", "aln": "--------------------------------------------------------MNKENTSRLPVM---------------SGKRAHTNSTDGEQQQPAQKKMR----KVEVE-----PSQRFRPAASVAPPRRPVAVKAPVKPLRPTGAATVAAAPARGDQRRPVAAVAKATAAVS----------RRPGWDLKGKVSDMEAKVQNYQSKVKTVNQENECLKDSIAKVQRRTADIEQENNGLRRRLG----DCEKEL----------------------VKLATVKDDLE-HTTKERDGLQKDLSKLTEEHKVLEGLRDHLESELRNIQTQLAIQTSALGRCQDSLKESQELARNLEETVARQREELHLGEMERRKLHNTIQELKGNIRVFCRVRPLLTGNQSDILHIQLPPHDN-------KALTLAKMEESHTGRT--TDTQKSYNFSFDRVFGPRSSQSEVFEEISLLVQSALDGYNVCCFAYGQTGSGKTFTMEGGE--QEELWGVIPRAVQQIFKSAKALSEQGWQYSFTASFVEIYNETLRDLLYKG-KPNKRPEHEIR---KVS--NNEITVTNLTYQKVNNEDEVHNLIMLANQNRSTARTCMNDHSSRSHSVFQLDIEGENTARDSKCKSMLCLVDLAGSERVQKSQSQG----ERFKEMTAINSSLTNLGIVIAALANKDS---FVPYRNSKLTYLLQNCLGGNSKTLMFANISPEEESFSESLNSLRFASKVNDCVIGTASANKK--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20480-1", "uniprot_id": "NCD_DROME", "id": "P20480-1", "name": "Protein claret segregational", "aln": "-----------MESRLPKPSGLKKPQMPIKTVLPTDRIRAGLGGGAAGAGAFNVNANQTYCGNLLPPLSRDLNNLPQVLERRGGGARAASPEPMKLGHRAKLRRSRSACDINELRGNKRTAAAPSLPSIPSKVSRLGGALTVSSQRLVRPAAPSSITATAVKRPPVTRPAPRAAGGAAAKKPAG----TGAAASSGAAAAAPKRIAPYDFKARFHDLLEKHKVLKTKYEKQTEDMGELESMPQQLEETQN----KLIETE----------------------SSLKNTQSDNE-CLQRQVKQHTAKIETITSTLGRTKEELSELQAIHEKVKTEHAALSTEVVHLRQRTEELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDES--------------TVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVP----ESVGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNE-----QKDMEIR---MAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSESPKTS--------TRMTETKNINRSLSELTNVILALLQKQD---HIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVANSSTQSNNSGSFDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17119-1", "uniprot_id": "KAR3_YEAST", "id": "P17119-1", "name": "Kinesin-like protein KAR3", "aln": "MESLPRTPTKGRSTQHLSTPSPKNDILAMNGHKRRNTTTPPPKHTLLKPQRTDIHRHSLASQSRISMSPNRELLKN----YKGTANLIYGNQKSNSGVTSFYKENVNELNRTQAILFEKKATLDLLKDELTETKEKINAVNLKFETLREEKIKIEQQLNLKNNELISIKEEFLSKKQFMNEGHEIHLKQLAASNKKELKQMENEYKTKIEKLKFMKIKQFENERASLLDKIEEVRNKITMNPSTLQEMLNDVEQKHMLEKEEWLTEYQSQWKKDIELNNKHMQEIESIKKEIENTLKPELAEKKKLLTEKRNAYEAIKVKVKEKEEETTRLRDEVALKQKTNLETLEKIKELEEYIKDTELGMKELNEILIKEETVRRTLHNELQELRGNIRVYCRIRPALKNLENSDTSLINVNEFD------------DNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPG------DGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRSDNNNKEDTSIGLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSERINVSQVVG----DRLRETQNINKSLSCLGDVIHALGQPDSTKRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLVSRK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . . . :. : .: . . .. . . : : : .. . . : *. : . : : . . . . : : * : *: *** : :*:*****:**:** * . . : *.**::* . : ::*: :. *:**:**** :* ***********:** . *:** :: :*. . ** *.. . ::***** : *** . . :: .: ::* : . : :: *. *:.* *. *.:*****:: :.: * :: . . : ******** . . *: * ** **: * ** ** : :. .:*:******:** .* *.:* *** *:** .. ..*:::*****:.**. : . . ", "identical_positions": 115, "similar_positions": 130, "identity": "14.76%" }, { "cls_id": "homologset.agr.MGI:2137431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPN3-1", "uniprot_id": "BPIB1_RAT", "id": "A0JPN3-1", "name": "BPI fold-containing family B member 1", "aln": "MTNPWIVSLL---LGATLVQANLYPPAVLNLGPEVIKKHLTQALENHDATAILQELPLLRGMQDK-SGSIPILDSFVNTVLRYIIWMKVTSANILQLVVQPSTYDQELVVRIPLDMVAGLNTPLIKTIVEFQMSTEVQALIRVERSKNGPARLNLSDCSSNESTLRLSLLHKLSFVVNSLAKNVMNLLMPALPQIVKSHLCPVIQQAFDDMYEDFLRLTTAPIALSPGALEFDLLSPAIQDSNILFNLKAKLLDSQARVTNWFNGSATPLMETTPDRAPFSLTVRQDLVNAIVTTLIPQEELVILLRFVIPDVARQLQMDIKEINAEAANKLGPTQMLKIFTHSTPHIVLNEGGATAAQSVVLEVFPTNTDVRPFFSLGIEASYEAQFFIAENRLMLNFNNVSIERIKLMISDIKLFDPEVLKDTLTKILEYTLLPNENGKLRTGIPMSMPKALGYEKAMWSVSKGALKLTPASS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61114-1", "uniprot_id": "BPIB1_MOUSE", "id": "Q61114-1", "name": "BPI fold-containing family B member 1", "aln": "MAGPWIITLLCGLLGATLVQANVYPPAVLNLGPEVIQKHLTQALKDHDATAILQELPLLRAMQDK-SGSIPILDSFVHTVLRYIIWMKVTSANILQLDVQPSTYDQELVVRIPLDMVAGLNTPLIKTIVEFQMSTEVQALIRVERSKSGPAHLNLSDCSSNESTLRLSLLHKLSFVVNSLAKNVMNLLVPALPQIVKNHLCPVIQQAFDDMYEDFLRLTTAPIALSPGALEFGLLSPAIQDSNILLNLKAKLLDSQARVTNWFNNSATSLMETTPDRAPFSLTVRQDLVNAIVTTLVPKEELVILLRFVIPDVARQLQMDIKEINAEAANKLGPTQMLKIFTHSTPHIVLNEGSARAAQSVVLEVFPTNTDVRPFFSLGIEASYEAQFFTEDNRLMLNFNNVSIERIKLMISDIKLFDPEVLKDTLTKILEYTLLPNENGKLRTGVPMSMSKALGYEKAMWSVSKGALKLTPASS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDL5-1", "uniprot_id": "BPIB1_HUMAN", "id": "Q8TDL5-1", "name": "BPI fold-containing family B member 1", "aln": "MAGPWTFTLLCGLLAATLIQATLSPTAVLILGPKVIKEKLTQELKDHNATSILQQLPLLSAMREKPAGGIPVLGSLVNTVLKHIIWLKVITANILQLQVKPSANDQELLVKIPLDMVAGFNTPLVKTIVEFHMTTEAQATIRMDTSASGPTRLVLSDCATSHGSLRIQLLHKLSFLVNALAKQVMNLLVPSLPNLVKNQLCPVIEASFNGMYADLLQLVKVPISLSIDRLEFDLLYPAIKGDTIQLYLGAKLLDSQGKVTKWFNNSAASLTMPTLDNIPFSLIVSQDVVKAAVAAVLSPEEFMVLLDSVLPESAHRLKSSIGLINEKAADKLGSTQIVKILTQDTPEFFIDQGHAKVAQLIVLEVFPSSEALRPLFTLGIEASSEAQFYTKGDQLILNLNNISSDRIQLMNSGIGWFQPDVLKNIITEIIHSILLPNQNGKLRSGVPVSLVKALGFEAAESSLTKDALVLTPASLWKPSSPVSQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.** .:** *.***:**.: *.*** ***:**:::*** *::*:**:***:**** .*::* :*.**:*.*:*:***::***:** :****** *:**: ****:*:********:****:******:*:**.** **:: * .**::* ****::...:**:.*******:**:***:*****:*:**::**.:*****: :*:.** *:*:*...**:** . ***.** ***:...* : * *******.:**:***.**:.* .* *. **** * **:*:* *::::. **:::** *:*: *::*: .* ** :**:***.**::**:*:.**.:.:::* * .** :******:. :**:*:****** ****: ::*:**:**:* :**:** *.* *:*:***: :*:*:. ****:*****:*:*:*: ****:* * *::*.** ***** ", "identical_positions": 265, "similar_positions": 149, "identity": "54.75%" }, { "cls_id": "homologset.agr.MGI:2137495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5I7-1", "uniprot_id": "MYCD_RAT", "id": "Q8R5I7-1", "name": "Myocardin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLGSEHSLLIRRKFRSVLQLRLQQRRTQEQLANQGLIPPLKSPTEFHDPRKKLDSAKTEDSLRRKVRNRSDRASLVNMHILQAS--TAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEVSLSKAADAFAFEDDSSRDGLSPDQARSEDPQGSGGSTP--------------DIKSTEAPLAGPLDTIQDLTPGSESDKNDTASQLSNQSDSGKQVLGPLSTPIP-------------------------------------------------------------------------VHTAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPP---MDSAYARLLQQQQLFLQLQILSQQQQQQQQQQQQQQQQQQQQ-RFSYPGMHQAHLKEPNEQMTRNPNSSSTPLNNTP-------------------------------------------LSPVKNSLSGQTGVSSLKPGPLPPN---------------------------LDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPFQ-----DCAGNPVPNFGDITTV-----------------------------------------------TFPVTPNTLPSYQSSPS------------------------------------------------------------GFYHFGSTSSSPPISPASSDLSAAGSLPDTFTDASPG-FGLHASPVPACTDESLLSSLNGGSGPSEPDGLDSEKDKMLVEKQKVINQLTWKLRQEQRQVEELRMQLQKQK-SGCNDQKPLPFLATTIKQE--------------------------------DVSSCPFAAQQASGKGQGHSSDSPPPACETAQLLP-------------------HCVESSGQTHVLSSTFLSPQCSPQHSPLGTLKSPQHISLPPSPNNHYFLASSSGAQRENHGVSSPNSSQGC-AQMTGLQSSDKVGPTFSIPSPTFPK--SSPTVPEITQ-PPSYEDAVKQQMT--------------------------------------------RSQQMDELLDVLIESGEMPADAREDHSC------------------------------LQKIPKIPGSSCSPTTILPKSSASFEQASSGGQISFDHYATDSEEHLEVLLNSHSPIGKVSDVTLLKIGSEEPP----------------------------------------FDGIMDGFPGKAAEDLFSAHELLPGPLSPMHTQLSPPSVDSS-----------GLQLSFTESPWETMEWLDLTPPSSTPG--FSNLTSSGPSIFNIDFLDVTDLNLNSPMDLHLQQW--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIM5-1", "uniprot_id": "MYCD_MOUSE", "id": "Q8VIM5-1", "name": "Myocardin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLGSEHSLLIRRKFRSVLQLRLQQRRTQEQLANQGLIPPLKGPTEFHDPRKQLDSAKTEDSLRRKGRNRSDRASLVTMHILQAS--TAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEVSLSKAADAFAFEDDSSRDGLSPDQARSEDPQGSTGSTP--------------DIKSTEA----PLDTIQDLTPGSESDKNDAASQPGNQSDPGKQVLGPLSTPIP-------------------------------------------------------------------------VHTAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPP---MDSAYARLLQQQQLFLQLQILSQQQQQQQQQQQQQQQQQQQQQRFSYPGMHQTHLKEPNEQMARNPNPSSTPLSNTP-------------------------------------------LSPVKNSISGQTGVSSLKPGPLPPN---------------------------LDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPFQ-----DCAGNPVPNFGDITTV-----------------------------------------------TFPVTPNTLPSYQSSPT------------------------------------------------------------GFYHFGSTSSSPPISPASSDLSAAGSLPDTFTDASPG-FGLHASPVPACTDESLLSSLNGGSGPSEPDGLDSEKDKMLVEKQKVINQLTWKLRQEQRQVEELRMQLQKQK-SSCSDQKPLPFLATTIKQE--------------------------------DVSSCPFAPQQASGKGQGHSSDSPPPACETAQLLP-------------------HCVESSGQTHVLSSTFLSPQCSPQHSPLGGLKSPQHISLPPSPNNHYFLASSSGAQRENHGVSSPSSSQGC-AQMTGLQSSDKVGPTFSIPSPTFSK--SSSAVSDITQ-PPSYEDAVKQQMT--------------------------------------------RSQQMDELLDVLIESGEMPADAREDHSC------------------------------LQKIPKIPGSSCSPTAIPPKPSASFEQASSGGQMAFDHYANDSDEHLEVLLNSHSPIGKVSDVTLLKIGSEEPP----------------------------------------FDSIMDGFPGKAAEDLFSAHELLPGPLSPMHAQLSPPSVDSS-----------GLQLSFTESPWETMEWLDLTPPSSTPG--FSNLTSSGPSIFNIDFLDVTDLNLNSPMDLHLQQW--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZQ8-1", "uniprot_id": "MYCD_HUMAN", "id": "Q8IZQ8-1", "name": "Myocardin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLGSEHSLLIRSKFRSVLQLRLQQRRTQEQLANQGIIPPLKRPAEFHEQRKHLDSDKAKNSLKRKARNRCNSADLVNMHILQAS--TAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPVDSAVKEAIKGNQVSFSKSTDAFAFEEDSSSDGLSPDQTRSEDPQNSAGSPP--------------DAKASDTPSTGSLGTNQDLASGSENDRNDSASQPSHQSDAGKQGLGPPSTPIA-------------------------------------------------------------------------VHAAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPP---MDSAYARLLQQQQLFLQLQILSQQQQQQQH-------------RFSYLGMHQAQLKEPNEQMVRNPNSSSTPLSNTP-------------------------------------------LSPVKNSFSGQTGVSSFKPGPLPPN---------------------------LDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPFQ-----DCSGNPVPNFGDITTV-----------------------------------------------TFPVTPNTLPNYQSSSSTSAL------------------------------------------------------SNGFYHFGSTSSSPPISPASSDLSVAGSLPDTFNDASPS-FGLHPSPVHVCTEESLMSSLNGGSVPSELDGLDSEKDKMLVEKQKVINELTWKLQQEQRQVEELRMQLQKQKRNNCSEKKPLPFLAASIKQEE-------------------------------AVSSCPFASQVP-VKRQSSSSECHPPACEAAQLQPLG---------------NAHCVESSDQTNVLSSTFLSPQCSPQHSPLGAVKSPQHISLPPSPNNPHFLPSSSGAQGEGHRVSSPISSQVCTAQMAGLHSSDKVGPKFSIPSPTFSK--SSSAISEVTQ-PPSYEDAVKQQMT--------------------------------------------RSQQMDELLDVLIESGEMPADAREDHSC------------------------------LQKVPKIPRSSRSPTAVLTKPSASFEQASSGSQIPFDPYATDSDEHLEVLLNSQSPLGKMSDVTLLKIGSEEPH----------------------------------------FDGIMDGFSGKAAEDLFNAHEILPGPLSPMQTQFSPSSVDSN-----------GLQLSFTESPWETMEWLDLTPPNSTPG--FSALTTSSPSIFNIDFLDVTDLNLNSSMDLHLQQW--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGQ6-1", "uniprot_id": "A0A8M2BGQ6_DANRE", "id": "A0A8M2BGQ6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLSSEHSVLIRSKFKSVLQLRLQQRRTREQISDQAVMPPLKSPAAFHEQRKNLERSKNGDYLKHKIRSRSEKSELANMRILHD----GEGPTADTHSRLKRARLT-----------------EQNMSPLQEDTDTVNDGLQQ------DSYTFEEDSSS-----EESLLEN-KSSGSCSP--------------TADSSRQ-------------HGSQSKDGSSQNQDENMTKSQE------NPPVP-------------------------------------------------------------------------VPAIVKSKMS--EKNRHKKPKDMKPKVKKLKYHQYIPPDQKAERSPAPQ--MDSAYARLLQQQQLFLQLQILSQQKQQMQTQQTQMQTQTQQSFSYHTLGPHTHKQVSEAQASCSSSVHTSTSSSSSS-------------------------------------------SSPEKNSYC--SSISPVRPAPLPTN---------------------------LDDLKVSELRQQLRVRGLPVSGTKTALIQRLRPFR-----DSGCGSPLGPVDPSSS-----------------------------------------------TFPAS-----SFQPPPP----------------------------------------------------------SAGLHPFCS--STPPVSPASSDLSIS---ADSFSDATVSPFGTQPSPAHTEHTP------------------DAEKDKMLLEKQKVIEELMWRLQQEQRQVEELRTQLHRRR-LEPHAHTHTPFCSAVVKQE--------------------------------PLSSSCVELQTSGGVCAFLSPQCSP--QESPLNKP--------------------CSSPQSTHTSPAHTHLLTHTLNHNNTSGSRGSIQHQQKSSAPP---LSCSYSSEQRSVQLYCSPSEHSISSRAAAKSRSAAPQREARSPSSPAIFC--SSDCPASVSKRPPCYQDAVKQQMV--------------------------------------------RSQQMDELLDVLIESGVSPSGGRFHR---------------------------------------------------------------------PYDAHTDVQLEALLHRTHSQTHT----------------------------------------------------------------QTHTDPSAPAELLMEPLSPSAGKLA--VLEAQ-----------GLGLGFCESPWESMEWLDLTPPGSTFQSAVPPAATHTHNIFSSEFLDAADISLN------LDQW--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z043-1", "uniprot_id": "B7Z043_DROME", "id": "B7Z043-1", "name": "", "aln": "MPVIADAASDEPPAKCCKHCEESTQSVDGGPASWRLTLDQDLIDTLKGNFPSWFQGSAGGGGGAGGAASKQNPQQHNHQLAQQKHHQLVATSVIPITIDTKLAASNTNTLQQHQQQTAILGHSSSSASPASSVSSNSSKKSISSSLSSCSSSSSNSSSCGSNHCNSKSVSSGAKGAGSATASRFLNKSTSTSPTKSLSRTLKATQKPNGNHKVGQLVKSASLHSLSSGSSGSSSGNSASGSSSLLATISTSPLTTVELISSAACSGLLATRLSGKDLEHSFQDIILLHEAYDDMSEGEQRLHATFLGSSDDGNNSDCYDARQSPPKAIVDSSPLQPAMDKNKESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRPNREDLERLHILEEDECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEKIVKEGLVSFKATSEGLLTRPQHPHSYVTFDDDSLSSESDTRQTPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVKQETANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSIASPPPPPMTTTRLHLAPVSVKSDAPGKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQPEETSYQLMLEQQNCLLKFLENLNKNQSIIPAPSAPGVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHPPPLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQHLKRRNLPVSGPKPHLIERLKPYLPLEPLDSNVTPAPTSNNSNTTPEVITISDAMDTSNCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMDNTHPMTLQTILPPQPQTATIILTNEELLREQQRKIDELQRQLQRSQQELQKIRQRQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQVEKNFPAKVTVKATG--GNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQKQKAAAAAAAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLLTQKTQTVFIPFNNNNHINNASAKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQHMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPIETKSIITQQQLQQLQQQQQQQQQFQPVQQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAAALNGLLPLVKIKEEPVQSPAPSAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPESAALEPITPLTPLPELSMFNGATPTTAAGGASIVPLVPKLETPVTPVQNLDVAMDTNVQHVGFASNQAPNHVFIESIDMASPLQTDSSAIDAESVAKTLDIFLEQHHATPPPSTPPKSCHSGSEKPNSPDAKLNHFDEYELLELMSQQLEMDMGDDSSGYCHASAAKSSNNNGNLRRDLNPSLQPSINELLDASSPDNVLLNNNTGADVDFDADSFVAQLSQHVTGNGNSPGVNCNGSIESSSSAVNSHFGSHSTPMDCDDFESTLNSFMQAVTQPQAGQHVEYATSTSMANGTGGGMGVDNGTGGAVDAFNASGDIFDLFNMDDYKMNWAAGDFTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::.*. * :. *:::* **.:.*: :*.::*.** .. :*: *:*: * : *: * :.* : .* ::**. : . . : **:***: ::*: :. . . :. . : . :: .. ..: .* : ..: .. : .* . . . ***. .***:*. .. .*.:.:*:*:* * . * :. :::* :*:**: :*:: :::*. . . :. . .: ::. : :. * * *. *:.:***:*:*:*: *.*****.*. *::**:*: *. . : .: *.* : *. .. : : : . * : : . . ... : . * . .:.: : :* * ::* :::::: . * :::: : .: :*: ... . : . . * :. * .. . .. . : . :* : . . :. . . . .. . ** *::*.** . :*:*:.::**:**:.* * .. . : : : . : : . * *.* :::. * :.* ..: : .:* ..: . .. .* . : *:.: ", "identical_positions": 105, "similar_positions": 253, "identity": "5.87%" }, { "cls_id": "homologset.agr.MGI:2137512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKB5-1", "uniprot_id": "ARI4B_RAT", "id": "Q9JKB5-1", "name": "AT-rich interactive domain-containing protein 4B", "aln": "MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRHDSSTVEVQDDHIKG---PLKVGAIVEVKNLDG-AYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAESETLDQLPLTNPEHFGTPVIGKKTNRG-RRSNHIPEEESSSSSSDDDEDDRKQTDELLGKVVCVD-YISLDKKKALWFPALVVCPDCSDEIAVK-KDNILVRSFKDGKFTSVPRKDVHEITSDTAPKPDAVLKQAFDQALEFHKSRTIPANWKTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIDFQMALP--------------------------EKVLNKPCKDCEN-KEIKVKEESDAEIKEVNVEDSKNMIPKEETPAEDESERKENIKPSLGSKKGLLECIPAQSDQEKEANITKLEEKESLEDKD----------------------------------------------------------------------------------------------------------------GATARAEEALSTEVDAEEEQARSG---------------------------------------------------------------------------------------YDEWIKADKIVRPADKN-----------------------------------------------------------------------------------------------------------------------VPKIKHRKKIKNKLDKEKDRDEKYSPKN---CKLRRLSKSPFQSNPSPEMVSKLDLADAKNSDTGHIKSIEITSILNGLQASESSAEDSEQEEERCAQDPESSSKDESKVEHSAHSRSELISKEELSSPSLLEENKVHPDLVIAK-----------------------TVSKSPERLRKDVEAISEDTDFEEEDEITKKRKDVKKDTTDKALKPQTKTWGKDRYCIQTNCLQSGSPGKKEDRTKSKEPLCTGNSSNSSSDEDEEEKSKAKMTPTKK-------YNGLEEKRKSLRTTSFYSGFSEVAEK-----------------------------------RIKLLNNSDERLQNNRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPH-------AAPDEGTVEESLQTVAEEESCSPNMELEKPLPTSVDSKPVEEKPLEVSDRKTEFPSSGSNSVLN-----------------TPPTTPESPSSVT------------VTETSQQQSSVTVSVPLPPNQEEVRSIKSETDS-TIEVDS---------VVGELQDLQSEG----NSSPAGFNASVSSSS-------------------------------------------------------SNQPEPEHPEKACTGQKRVKDTQGVGSSSKKQKRSHKATVVNNKKKGKGTNS---------------------------SDSEDLSAGESVTKTQAIKSVPTGMKTHNSKSPARIQSPGKCGK---------------NGDKDPDLKEPSNRLPKVYKWSFQMSDLENMTSAERISILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERES---AATSSSS--------------------------------------------------------------------SSPSSSSITAAVMLTLAEPSMSSASQ-NGMSVECR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2CG63-1", "uniprot_id": "ARI4B_MOUSE", "id": "A2CG63-1", "name": "AT-rich interactive domain-containing protein 4B", "aln": "MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRHDSSTVEVQDDHIKG---PLKVGAIVEVKNLDG-AYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAESETLDQLPLTNPEHFGTPVIGKKTNRG-RRSNHIPEEESSSSSSDDDEEERKQTDELLGKVVCVD-YVSLEKKKAMWFPALVVCPDCSDEIAVK-KDNILVRSFKDGKFTSVPRKDVHEITSDTVPKPDAVLKQAFDQALEFHKSRAIPANWKTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIDFQMALP--------------------------EKVLNKPCKDCEN-KEVKVKEESETEIKEVNVEDSKNVMPKEETPAEDESERKENIKPSLGSKKSLLECIPAQSDEEKEAHITKLEENENLEDKD----------------------------------------------------------------------------------------------------------------GGRARTEEAFSTEVDGEEEQARSGDETNKEEDEDDEEIEEEEEEDEEEDEDEDDDDNNEEEEFECYPPGMKVQVRYGRGKNQKMYEASIKDSDVEGGEALYLVHYCGWNVRYDEWIKADKIVRPADKN-----------------------------------------------------------------------------------------------------------------------VPKIKHRKKIKNKLDKEKDRDEKYSPKN---CKLRRLSKSPFQSNPSPEMVSKLDLADAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDERCTQDVDNIGKDESKVEHSTHSRNELISKEEQSSPSLLEENKVHTDLVIAK-----------------------TVSKSPERLRKDMEAISEDTDFEEEDEITKKRKDVKKDTTDKALKPQTK-RGKRRYCSADECLQTGSPGKKEDRTKSKEPLCTENSSNSSSDEDEEEKSKAKMTPTKK-------YNGLEEKRKSLRTTSFYSGFSEVAEK-----------------------------------RIKLLNNSDERLQNNRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPH-------PAPDEGAVEESLQTVAEEESCSPIMELEKPLPASVDNKPIEEKPLEVSDRKTEFPSSGSNSVLN-----------------TPPTTPESPSSVT------------ITEASQQQSSVTVSVPLPPNQEEVRSIKSETDS-TIEVDS---------VVGELQDLQSEG----NSSPAGFDASVSSSS-------------------------------------------------------SNQPEPDNPEKACTGQKRVKDTQGVGSSSKKQKRSHKATVVNNKKKGKGTNS---------------------------SDSEELSAGESVTKTQTIKSVPTGMKTHNSKSPARVQSPGKGGR---------------NGDKDPDLKEPSNRLPKVYKWSFQTSDLENMTSAERISILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERES---AATSSSS--------------------------------------------------------------------SSPSSSSITAAVMLTLAEPSMSSASQ-NGMSVECR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4LE39-1", "uniprot_id": "ARI4B_HUMAN", "id": "Q4LE39-1", "name": "AT-rich interactive domain-containing protein 4B", "aln": "MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRHDSSTVEVQDDHIKG---PLKVGAIVEVKNLDG-AYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAESETLDQLPLTNPEHFGTPVIGKKTNRG-RRSNHIPEEESSSSSSDEDEDDRKQIDELLGKVVCVD-YISLDKKKALWFPALVVCPDCSDEIAVK-KDNILVRSFKDGKFTSVPRKDVHEITSDTAPKPDAVLKQAFEQALEFHKSRTIPANWKTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIEFQMALP--------------------------EKVVNKQCKECENVKEIKVKEENETEIKEIKMEEERNIIPREEKPIEDEIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKD----------------------------------------------------------------------------------------------------------------DDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEE-EEEEEDEDDDDNNEEEEFECYPPGMKVQVRYGRGKNQKMYEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKADKIVRPADKN-----------------------------------------------------------------------------------------------------------------------VPKIKHRKKIKNKLDKEKDKDEKYSPKN---CKLRRLSKPPFQTNPSPEMVSKLDLTDAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKVHADLVISK-----------------------PVSKSPERLRKDIEVLSEDTDYEE-DEVTKKRKDVKKDTTDKSSKPQIK-RGKRRYCNTEECLKTGSPGKKEEKAKNKESLCMENSSNSSSDEDEEE-TKAKMTPTKK-------YNGLEEKRKSLRTTGFYSGFSEVAEK-----------------------------------RIKLLNNSDERLQNSRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPH-------PAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEFPSSGSNSVLN-----------------TPPTTPESPSSVT------------VTEGSRQQSSVTVSEPLAPNQEEVRSIKSETDS-TIEVDS---------VAGELQDLQSEG----NSSPAGFDASVSSSS-------------------------------------------------------SNQPEPEHPEKACTGQKRVKDAQGGGSSSKKQKRSHKATVVNNKKKGKGTNS---------------------------SDSEELSAGESITKSQPVKSVSTGMKSHSTKSPARTQSPGKCGK---------------NGDKDPDLKEPSNRLPKVYKWSFQMSDLENMTSAERITILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERES---AATSSSS--------------------------------------------------------------------SSPSSSSITAAVMLTLAEPSMSSASQ-NGMSVECR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKB0-1", "uniprot_id": "A0A8M2BKB0_DANRE", "id": "A0A8M2BKB0-1", "name": "AT-rich interactive domain-containing protein 4B", "aln": "MKTLEEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKAKVTFRPDASTAEVHDEHIRG---LLKVGAVVEARNQDG-VYQEATINKLTDASLYTVVFDDGDEKTLRRSSLCLKGARHFAESETLDRLPLTNPEHFGTPVIGKKGNRGGRRSNPIQEEESSSSSSEEEEGDQQQNEELYGKVVCVEGVLTNDKKKSTWYPALVISPDCHEDVTLK-KDNVFVRSFKDGKFYTVLRKDIRELDEDKAPKADAGLKPALDAAWEFQRNGAVPNTWRTEVKDESSSSEDEEEEEEE--EQEEEASSEEEEEEVEPFPEEKDNFLQQLYKFMEDRGTPINKRPVLGYKNLNLFKLYRLVHKLGGFDNIESGSVWKQVYQDLGIPVLNSAAGYNVKCAYRKYLYGFEDYCTSTGISFRMDLP--------------------------YKTGEKTSCKTEVKAEEVISTEN---TVSLNTPEEHKSITESERSCTRHLLKEEKTETVTPCEEKADISGENKEDEKHAEEENEMNEEVKQCMST----------------------------------------------------------------------------------------------------------------GETDVTEDVKEEPCEEPDDKDLSGDVSSQEWEEG--------------------------QEFECYPPGMKVQVRYGRGRSLKTYDATVKESNLEGGEVLYLVHYCGWNVRYDEWIKADKIVRPANKN-----------------------------------------------------------------------------------------------------------------------VPKIKHRKKIKNKAERERDRIERLADREDLPSSKNRINR-LSKVNSGGDVFSKMEECVDK----GNQQSIEITSILNGLPGSDSSTDDSEREED---EDADHDEDDDHPGAHKADPPQ---SQHWEKNSSPPEAPKTPADAEQEP-----------------------TLQDSTETPKR--------------KELDTNASAGRRKKAENTSKSPAK--GKTRNSRGGEWLQSGSPKKLEDRGE------------SSSEDEPKGHPKNKSSPSKK-------YNGVKEKSKSR------GAFWEIPEK-----------------------------------RAKVSAGIEERSPGCRTKGQKDVWSSIQVQWPKKTLKELFSDSDTEAANSPPP-------AGP---------------EACS-------------ESARDEEEEEEEEEKLQEHPSSGTNSVLN-----------------TPPTTPESPAAAEGPAETLPEVRAPSPPAALAASPPPVSLPEEPLMEEPAGGRSESDSSTVEVES---------LGGEIQEMNAEEG--AGSPSKAFDGNMSCNSNSNCSLT---------------------------------------------LSNSSQQESEQKAKASSSQKRHKESQG-GGATKKHKRSHKNLSLQPKKSRKAAHS---------------------------SDSEDQCISESTAKSPPVKSSGAELKSSITHK-CSSRTPPSGQQ---------------RYHKHTDTEHSHGRT----RWSFQMSDLEKMSSLERISFLQEKLQDIRNHYLLLKSEVASIDRRRKRIKKKERETGAAAASSSSS--------------------------------------------------------------------SSPSSSSLTAAVMLTLAEPTVSAASQTAGVSVECR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWP5-1", "uniprot_id": "Q9VWP5_DROME", "id": "Q9VWP5-1", "name": "", "aln": "MQQMDDPPSLPVGTEVSAKYKGAFCEAKVSKVVRNIKVKVAYKQGLGSGIVSDDAIKAPTGQLRVGAVVEVRHPDRKELVEATITKIQDCSQYTVVFDDGDITTLRRTALCLKSGRHFNESETLDQLPLTHPEHFGNPVVG---GRRGRRRGHLNEDSSEDDDESDAKEVVNEKEENIGKVVCVE-TESKKKDKEKWFPALVVAPTAQATVRIRVKDEYLVRSFKDGRYYTVPKKEATEFTREVASKQD---VPAVQAALEFLDSSVLPAHWDRDSLFGLTNISSDDEGEIDSDSSDDEP------------HEEKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRANSVASPKPMETMKTETISKLAQPNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSESSVVVEPPKKQRKGSAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAAASTATNLSSATSGGSATIATTAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASASSKANSAEMQRSRDASPSVAAPPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKDKDKEEKQASSGKRKKEKISVEKIDTGDFVVGIGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRGVPMYLVHYTGWNNRYDEWVPRERIAENLTKGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGSQPPGVSDKQPGKDGCSKMSPSSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTGGAKRGRGRSDSMPPRSTTPSSVVAHSGRTKSPAASQPQLQQQMKKRPTRVVPGTTTPRRVSDASMASESDSDSDEPVRRPKRQSAKDKPQAGKAQPPGKGRLASSASSTAPAAHPSDDSEEDEEEEEPSAARAASSKQQQQQASSLRGSRAGGNRAMSSGAASAKGRDYDLSEIRSELKGFQPKLLTNAASNEERKDLAKKEPSDEPALQDIKKEPKLESSAKSSSTELSSETESYADEDSQSSDYRKQLKGSGAGKKEPTASPSKLHHEPVTKRELAVKEEPLKIEPKTEPKEEETKSKPFLSGADIKPTALIAPARFGNTSAAQAASSSGSSSTTAKYTSVIVEKPLTIGGKKSVEQHVPKKAELLKKQSGGAGGTAASSSAASQESKKFAEPVASLKVEMPAACSPSSSSSSSSSFCSTGSAVSSSSATRSLPDMSKLEISSGTVPGATPGAAALQPSNVAQVSSSGAAKESKYSSSGGAAAGSGISMRKLLSSDVYEFKDTEPFEFEKRISPMASVGGTVAAAATAAGAMAAAGAASVITTMVPTPGASGSGVAASASTSAPVVVGSAARKQALKASAIQHILEHQSPAAGRERGGYGGMTSSISLLTAPKLKKRGSPLKEAALCMEKAKTYKLDKDQVQQPVEQKTQQLIQPTLGPVESYGAGSPEAMSNLSTPTTSSGHAQLSASSTYSQLTPHHATPFDALRKSPSFNLNITALNEELAQTVQETTRALTDALQPPSTPVPPTVSASGSTPTAVTPVITAMPTAGTAGLSCPSTPPTGANPVLASPKLSTPPQAINASKQPPASHIVGSPFIETRNVFELSTSNEGSGYSSGESKDNKFEKLENVKILLAGAVGPFDLDAGSYEQKTSSIADKVLKAISQKKEEVENNKGKPPVEPAAAAKTPGREDVVPSPTAKLDLCSSAIKLDTLKLLSEPLKIQTGPLLGELYRPGPATSSPETKSILESSLPAKNSELSETIQKLECAIQQRKTPVGGALSLASSTAGTPPTAHTPNSTATAGAGFSDESMDSTDSEQRLVIEDVIAEEHTTTTTTGEQKSPGSQQEEGQTNTATMATAVTAETEGTSSSTPTPPVPAPVKLELGAKAMPGIQAPIPLKPAEGSSFAGKLTGVVQPPPLAKLQQQEELGQAQGQSKSISSFGIPIVLPEIPASVVVATPALMVASAATVMRHSPGSTPNSQAPVLISPKTFLTAPKVGEVGGLLLKAYTGVSGAVGAAPAGSVIASAGGGGTPTVISNFPQQQQQASVLQASSEMPANYVLDAEMAEPSNSSAPVVARPFVMHAVGKELFNVVAPAASSPLISDPHNESINLLCEETIPGSPAPNYGGTDQLPTAVNSALAIVGITPLPPDTPPPVPVAAIQQQQQHQLQSGQQQQAAKTGEVNPSGPNSSPDSASQDESGEEAKKNAGLEHEDSTGLGALNKRKRNRKPLPMSAQTAAAVAAQLQSLGKRRRQVSGMRNQKTTTTAAGSDTDDNSDNIAPNAGQQQQQPRQSARQHMMPQSNAQQQQQQQLLQQQQTQLPQGIQSTNSSGVRPCPYNFLVELDPALSSDECITILRKQIQDLRKAYNTIKGELAVIDRRRKKLRRREREKKQQQLQSQQQGKICA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :::** *.***:*****:*******:... * :*.**::: . .: * *: *:. *:***:**.:: * **.*.*: *.* ********* .****::****. *** ******:****:*****.**:* .* ** . : *:.*......: : :: :* ******: : .*.* *:****:.* . : :: **: :*******:: :* :*: *: : ..* * *.: * ** . .:* * : :. . ::* * : ..:.* **::.*: ****:*:*****:** * : ::::*::*:* *:* **::.: * ** : **:. . :. ** **:*:* : :: . . .: * :. .* . : . . . : . .: . .*. :: . .: : : ::: . . . .:: . ****: ::*.. *. . : * : *. : : :: : : . . . : *. : : . .. : . . :*: .* :* : .:: : . .: * :. .. .. * .: . . : ..:: : :. . : . : *: ... * * . . : .: : * *.:: .* . * .: . : :: . . :.. .* : * :** :. : : :: *.. .. * .* : : . : :..*** :. . * * *. : . .. .* . * . : : * : * . :*.: . . .:.. *. * . ..: : .: . .:* ..:: .: .*: .: :. . : * . . * :.. .:.. : : : : . :* . . . *.. .. . : *: * :: :. . ::*::.:.: : * . *..:* ::* . . .: *. ..*::** : :* : *: .: . .:** ", "identical_positions": 219, "similar_positions": 382, "identity": "8.74%" }, { "cls_id": "homologset.agr.MGI:2137513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPQ0-1", "uniprot_id": "NCKX3_RAT", "id": "Q9EPQ0-1", "name": "Sodium/potassium/calcium exchanger 3", "aln": "------------------------------RDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLIGEDRKWMVGRKLMQVNDTLT----SEDAGLRSSKNCTEPALHEFPRDIFSNEDRRQGAVVLHVLCAMYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEKVSWWESLVLVLMYLIYIIIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRR-----DDIVAEADNETENENED-ENNENDEE--EDEDDDEGPYTPFDPPSGK--LETVKWAFTWPLSFVLYFTVPNCNKPHWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYG---SYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLFLYGVFLCFSIMTEFNVFTFVNLPMCGD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PD7-1", "uniprot_id": "NCKX3_MOUSE", "id": "Q99PD7-1", "name": "Sodium/potassium/calcium exchanger 3", "aln": "-----------MPPPGDQDCA-RRRSRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLIGEDRKWMVGRKLMQVNDTLT----SEDAGLQSSKNCTEPALHEFPRDIFSNEDRRQGAVVLHVLCAMYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRR-----DDIVAETDNETENENEDNENNENDEEEEEDEDDDEGPYTPFDPPSGK--LETVKWAFTWPLSFVLYFTVPNCNKPHWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYG---SYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLFLYGVFLCFSIMTEFNVFTFVNLPMCGD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC58-1", "uniprot_id": "NCKX3_HUMAN", "id": "Q9HC58-1", "name": "Sodium/potassium/calcium exchanger 3", "aln": "-----------MRPSGDEDRARRRRRRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRKWMMARKLMQVNDTLT----SEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRR-----DDVVAEAGNETENENED---NENDEEEEEDEDDDEGPYTPFDTPSGK--LETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYG---SYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMCGDH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T746-1", "uniprot_id": "A0A8N7T746_DANRE", "id": "A0A8N7T746-1", "name": "", "aln": "MDGDACVRVWTRPLQVMLQQKKIKARRKKRKELFGGQMCFMGLLLLAVSGLSSLAENSGYGIPSLSAEDSKKWESRRLLQDFDIDSNYTDEVQLGPNADKNCTPPGIHEFPDDIFTQQERLEGAVALHVLCAMYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVTWWESLILIVLYLVYILIMKFNSRVVHFIERRKKNPANLGNGTASNTDIDDG--CDATVVLLKKANFHRKPSVLMVDELLSAYPHQLTFSEAGMRIMITSHFSPRTRLTMASRMLITERQRLINSR-FSNGDSEVTVKMPGKRGVENG---LAGPDRGLNGRKGGHHDDDRGGAEAGTDTENENEDNENNENDEEE-EEEDENEGPYVPFRCPGGG--INKLKWLLAWPLSMLLFFTVPNSANPRWERWYMVSFISSTIWIAFFSYIMVWMVTVIGYTMGIPDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTLAINYG---STIHLNSKGLIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLCFSILIEFNIFTFVNLPTCREE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5LJX8-1", "uniprot_id": "Q5LJX8_DROME", "id": "Q5LJX8-1", "name": "", "aln": "-----------------------------------------------------------------------------MMRIRNMKSS---ISHILLFCYINCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKCAKGGVKQARSRSR--SSNCSIHTKNSNEKEPELVENRICQNMANIQLNGGLNKEQAKATSTSGAGTTAISITTSTMTTTLSTT----------------HSAGGGGGAVGL------------CSGPGAIVQMAPL-----DDAEAESHVAVAAADEG--------------RKEEG-YSLLSYPKDKSCFAQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVPWLIKAVFFPIQPGQNYVAINSAGLEYSAITLLSTLFLLYLTFSTNKFKLDKKVGTACLVMYLVFMVFASLIELNVFFRVNLPTCGRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : : . *** *.:.:** *:*:: :* .***.***:.::*:* ***:***::***::**** *::*:**********.:******..***.***:**:**************.: . **: :. .: *. * * *** * ::* ** .::**:* *:*:*:*: :* :*: :* :: . : : * . . . :.* .*. : *::: :. ..: : . * . .: : * ** : : . * *: : .: * . :: : :.*. :: * **: . :*. .:** * : * . : ..* : **: ::: :::*:. :.: :: : ::* . :**. :**::.**:*:** *: *** :*************:.::*:***::* *.*.:.******.****: **:** :::: . . : :** ** :*. **:::*: : . *:::***::* .**.:* **: *: : *:*:* **** * ", "identical_positions": 191, "similar_positions": 185, "identity": "28.42%" }, { "cls_id": "homologset.agr.MGI:2137520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9T2-1", "uniprot_id": "D4A9T2_RAT", "id": "D4A9T2-1", "name": "", "aln": "MNSHHV--VLTLASLMFLMCLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELTHHENLVSFLETVNQPHHQN-VSVPSNNVHAPFPSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECVGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP52-1", "uniprot_id": "TWSG1_MOUSE", "id": "Q9EP52-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKSHYI--VLALASLTFLLCLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQLHHQN-VSVPSNNVHAPFPSDKERMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZX9-1", "uniprot_id": "TWSG1_HUMAN", "id": "Q9GZX9-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKLHYVA-VLTLAILMFLTWLPESLSCNKALCASDVSKCLIQELCQCRPGEGNCSCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQPHHQN-VSVPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGH0-1", "uniprot_id": "TWS1A_DANRE", "id": "Q9DGH0-1", "name": "Twisted gastrulation protein homolog 1-A", "aln": "MRPALFLCPVLISVLFLLSSLSLISGCNKALCASDVSKCLLQGLCQCRPQEGNCSCCKECMLCLSSLWEECCDCVGMCNPRSYNDSPATSKSTVEELYRPIPSLFRALTEGDAPINMMVVSFPVAEELSHHENLVSFLETLDSQSQN--ISLP-----TSSAQD-DALCTVVYFDDCVSIRQCKQYCESMGGSKYRWFHNACCECIGPECLDYGSKTVKCMNCLI------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q98SR9-1", "uniprot_id": "TWS1B_DANRE", "id": "Q98SR9-1", "name": "Twisted gastrulation protein homolog 1-B", "aln": "MGSSSSSSVVLL--LLLLSSLSIALACNKALCASDVSKCLIQELCQCRPADGNCSCCKECMLCLGSLWEECCDCVGMCNPRSMSESPATGRSTVEDLFQPIPSLFRALTEGDAPTHTLVLTLPLAEELQYQHNLHNYLETLHNTQHNNTTSVPENSIHSSYHTQ-DKQCTVVYFDECVSIRQCKQYCESMGGSKYRWFHNACCQCIGPECVDYGSKSVRCLNCLY------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W494-1", "uniprot_id": "Q9W494_DROME", "id": "Q9W494-1", "name": "", "aln": "MEIWRSLTVGTIVLLAIVCFYGTVESCNEVVCASIVSKCMLTQSCKCELKN--CSCCKECLKCLGKNYEECCSCVELCPKPNDTRNSLSKKSHVEDFDG-VPELFNAVATPDEGDSFGYNWNVFTFQVDFDKYLKGPKLEKDGHYFLRTNDKNLDEAIQERDNIVTVNCTVIYLDQCVSWNKCRTSCQTTGASSTRWFHDGCCECVGSTCINYGVNESRCRKCPESKGELGDELDDPMEEEMQDFGESMGPFDGPVNNNY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZE5-1", "uniprot_id": "Q9VZE5_DROME", "id": "Q9VZE5-1", "name": "", "aln": "--------MKTLLTIYILLSFG-------------------------ELG----------LANMAQ---------------------MRKKSHTEEFEG-MPALFRAMSSS-PNDGYTYNWSVVSFSTN----------GKPGS---------------------GLNCTVLYLDQCTSWNKCRQTCLKTGATSYRWFHDGCCECVGELCMNYGVNESRCRLCPEP--GLEDEDD--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54356-1", "uniprot_id": "TSG_DROME", "id": "P54356-1", "name": "Protein twisted gastrulation", "aln": "-MQLLCYFVILFVGIAPWSSLANDDGCNEVVCGSVVSKCLITQSCQCKLND--CHCCKDCLNCLGELYIECCGCLDMCPKHKDVLPSLTPRSEIGDIEG-VPELFDTLTAE---DDEGWSTIRFSMRAGFKQRVQGGASGDAGNGNGNGNAGSAG----------VTLCTVIYVNSCIRANKCRQQCESMGASSYRWFHDGCCECVGENCLNYGINESRCRGCPEDQDQLLTADTVP-AEAEQDLERFFGNEEIEDEWGYGEEDEFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : :. :* :: :* ** ::: .: ***:*.:.* .:*: * . *.:. ****:.**:*:* *::** : :* * ", "identical_positions": 25, "similar_positions": 34, "identity": "9.36%" }, { "cls_id": "homologset.agr.MGI:2137586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M834-1", "uniprot_id": "DTBP1_RAT", "id": "Q5M834-1", "name": "Dysbindin", "aln": "MLETLRERLLSVQQD------------------------FTSGLKT------LSDKSKEAKVKSRPRTAPYLP--------KYSAGLDLLSRYEDTWAALHRRAKECADAGELVDSEVVMLSAHWEKKRTSLAELQEQLQQLPALLQDVESLMASLAHLETSFEEVENHLLHLEDLCGQCELERHKQAHARHLEDYKKSKRKELEAFKAELDTEHAQKILEMEHTQQLKLKERQKFFEEAFQQDMEQYLSTGHLQIAERREPMGSMSSMEVNVDVLEQMDLMDLSDQEALDVFLNSGGEDNTVISPGLE---MESNPSQNEMNLQIPNPSESASQPPASPSACTDLDT-------------ADAPLIQADEEEVQVDTALVTLNTDRKSTPGVSDDSDQCDSTQDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WZ8-1", "uniprot_id": "DTBP1_MOUSE", "id": "Q91WZ8-1", "name": "Dysbindin", "aln": "MLETLRERLLSVQQD------------------------FTSGLKT------LSDKSREAKVKGKPRTAPRLP--------KYSAGLELLSRYEDAWAALHRRAKECADAGELVDSEVVMLSAHWEKKRTSLNELQGQLQQLPALLQDLESLMASLAHLETSFEEVENHLLHLEDLCGQCELERHKQAQAQHLESYKKSKRKELEAFKAELDTEHTQKALEMEHTQQLKLKERQKFFEEAFQQDMEQYLSTGYLQIAERREPMGSMSSMEVNVDVLEQMDLMDISDQEALDVFLNSGGEDNIVMSPGVE---MESNPNQNEMSLQIPSPSESASQPPASPSACTDLDT-------------ADAPLIQSDEEEVQVDTALVTLHTDRKSTPGVSDDSDQCDSTQDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EV8-1", "uniprot_id": "DTBP1_HUMAN", "id": "Q96EV8-1", "name": "Dysbindin", "aln": "MLETLRERLLSVQQD------------------------FTSGLKT------LSDKSREAKVKSKPRTVPFLP--------KYSAGLELLSRYEDTWAALHRRAKDCASAGELVDSEVVMLSAHWEKKKTSLVELQEQLQQLPALIADLESMTANLTHLEASFEEVENNLLHLEDLCGQCELERCKHMQSQQLENYKKNKRKELETFKAELDAEHAQKVLEMEHTQQMKLKERQKFFEEAFQQDMEQYLSTGYLQIAERREPIGSMSSMEVNVDMLEQMDLMDISDQEALDVFLNSGGEENTVLSPALG---PESSTCQNEITLQVPNPSELRAKPPSSSSTCTDSATRDI-------SEGGESPVVQSDEEEVQVDTALATSHTDREATPDGGEDSDS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWE6-1", "uniprot_id": "DTB1A_DANRE", "id": "Q7ZWE6-1", "name": "Dysbindin-A", "aln": "MFENFREKLQTVQQD------------------------FTSGIKT------LSDKSKEAKVKKKQRRDEYLP--------QYSAGVELLSRYEDTWVALHKRAKESAKSGETVDGEVVMLCAHWEKRRGAVLELQEQLQQIPTFLSDLETITSRIAHLEADFEEMESRLVYLEDLCAQCEHQRFKQFQILQLENYKKKKRKELESCKAELDAEHAQKVLEMEHAQQVKLKERRKYFEEAFQQDMEQYLSTGYLQITDRRDPLGSMSSMEVNVDLLEQMDLTDVSDHEALDVFLSSVGEESSAVSPDAGGPSLEPGSSPSDISLKVPSQSELRHNISSISSSCTDTVSGTTEGPDEEESSSGDSPLVQSDEEEVHADTALMGLPETEALKS--SDDSDTQAP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVT5-1", "uniprot_id": "DTBP1_DROME", "id": "Q9VVT5-1", "name": "Dysbindin protein homolog", "aln": "MFGNLKKKLSSAIQEGLVISENLQQQYRQRVSSGNSGSSQASGITTPISPLGLNESLSSSRSSSLSLSAPFQLTDGVPSHLNVAAGCSLLAKYEDDWQQIHGANEKNAEKAAQIANQISGIQDQASHQHRIMSELNSSLAGIPTLIAQLQNSSQVLNSLEEMGKQLEIELEKLEDLREECELQEFILEQQFQLSRHKQKKLNELEQYRQQIAQKHQSKIKDQEQTLLKLQRERQAVFDDAFREDMEEYKQRGQLTKIQTTS-----NKLALEEVVLEAN---EVETKDALEQFLNG--------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .::::* :. *: :**:.* *.:. .:: . : :** .**::*** * :* :. *. . : .:: : : .::: : **: .* :*::: :::. : ** :::* .* **** :** :. : :*. :*:.* :*** : :: :* .* : *:: :**: *::**::***:* . * * : . ..: :: :** ::. ::**: **.. ", "identical_positions": 57, "similar_positions": 97, "identity": "14.04%" }, { "cls_id": "homologset.agr.MGI:2137594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5CD99-1", "uniprot_id": "Q5CD99_RAT", "id": "Q5CD99-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "--------------MASLRRVKVLLVLNLIAVAGFVIFLAKCRPIAVRSGDAFHEIRPRAEV-ANLSAHSASPIQDAVLKRLSLLEDIVYRQLNGLSKSLGLIEGYGGRGKGGLPATLSPSEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKELPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKAPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERKALRKSLKCKNFQWYLDHVYPEMRRYNNTIAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQNGAIMNKGTGRCLEVE-NRGLAGIDLILRSCTGQRWTIKNPIK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT15-1", "uniprot_id": "GLT17_MOUSE", "id": "Q7TT15-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 17", "aln": "--------------MASLRRVKVLLVLNLIAVAGFVIFLAKCRPIAVRSGDAFHEIRPRAEV-ANLSAHSASPIQDAVLKRLSLLEDIVYRQLNGLSKSLGLIEGYGGRGKGGLPATLSPSEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKELPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKAPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKAATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERKALRKSLKCKNFQWYLDHVYPEMRRYNNTIAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQNGAIMNKGTGRCLEVE-NRGLAGIDLILRSCTGQRWAIKNPIK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IS24-1", "uniprot_id": "GLT17_HUMAN", "id": "Q6IS24-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 17", "aln": "--------------MASLRRVKVLLVLNLIAVAGFVLFLAKCRPIAVRSGDAFHEIRPRAEV-ANLSAHSASPIQDAVLKRLSLLEDIVYRQLNGLSKSLGLIEGYGGRGKGGLPATLSPAEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKDLPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKVPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRKSLKCKNFQWYLDHVYPEMRRYNNTVAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQNGAIMNKGTGRCLEVE-NRGLAGIDLILRSCTGQRWTIKNSIK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZL6-1", "uniprot_id": "E7EZL6_DANRE", "id": "E7EZL6-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "MMRFTGFRTPKSFMAFVMRRWKILLVLNVFTVAGFITFWGKCNVRTTKGVGQQMAVDSRGQTNLNGSVQETSITHDVLLKRLGSLEDVVYRQLNGLSKSLGLIEGFGGRGRGGIPATLTPAEEKEAKFLREKYGYNAFLSDKISLDRSLPDYRPSKCKKAFFPRDLPQISIIFIFVNEALSVILRSVHSAVNHTPAHLLKEIILVDDNSDDVQLKGPLEEYVNKRYPGLIKIVRNQKREGLIRARIEGWKVATGEVTGFFDAHVEFTPAWAEPVLSRIKENHKRIILPSIDNIKDETFELERYENSGHGYNWELWCMYISPPKQWWDEGDTSAPIRTPAMIGCSFVVNREYFGDLGLLDAGMDVYGGENIELGIRVWLCGGSMEVLPCSRVAHIARTKKPYHSNIAFHTRRNALRVAEVWMDQYKSNVYLAWNLPMKNHGIDYGDVSERLALRKRLQCKSFDWYLDNIYPEMRRYNNTVFYGEIRNTNVTHLCVDQGIKENHTATLHPCHGWGPQLGRYTKEGYLFLGPLGSTG--EDTRCVVDDKISSYPQLLNCEKVSSVRQKTWHFAQNESIISRATGRCLEVVPANVYFGYALILRSCTGQKWNIKNLMKQDQGQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** *:*****:::****: * .**. :.:. . : .*.:. * *.:.:* :*.:****. ***:*****************:****:**:****:*:**::** :******::**:*******:*****:***: :.::******************************:**************: :** ******:******:*:******************.***:************..*********:**:**:*********::.**::*****.***.************:*** **.* ****************::**::****.**************:******************* *.****:***.*:*:************:***:**:*****::* *** ****** **** *:**.*:****::**********: ***:**.:...:*:*** ***** *:*********.******:*.**.**:* ****:**:. * ****:*:**.* * *:* ** :*:.:.******* . * *********:* *** :* ", "identical_positions": 422, "similar_positions": 118, "identity": "68.17%" }, { "cls_id": "homologset.agr.MGI:2137600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5M7-1", "uniprot_id": "A0ABK0M5M7_RAT", "id": "A0ABK0M5M7-1", "name": "RCC1-like G exchanging factor-like protein", "aln": "---MLAVARALLERRLSWPVPAREHWRPAGRSRSRREAAEAEADAPVFQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGLRPRRRIQPVPYRLELDHKISSAACGYGFTLLSSKTKDVTKVWGMGLNKDSQLGFHRSRK-DKTRGYEYVLEPSPVPLP---LDRPQETKVLQVSCGRAHSLVLTDREGVFSMGNNAHGQCGRKVVEDEVYSESHKVHRMQD-----FEGQVVQVVCGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSTPSKLGGDLAGVTVVQVATYGDCCLALSADGGVFGWGNSEYLQLA-SVTDSTQVNVPRCLPFSG-VGKVKQVACGGTGCAILNEEGHVFVWGYGILGKGPNLSETALPEMIPPTLFGLTEFNPEVKVSQIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRENESMRGPGGGQSRTPAPHLPSPKPRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYF5-1", "uniprot_id": "RCC1L_MOUSE", "id": "Q9CYF5-1", "name": "RCC1-like G exchanging factor-like protein", "aln": "---MLAAARALRGPRPRWPTPAREHWTPAGRSRSRREAAEAEADVPVFQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGLRPRRRIQPVPYRLELDHKISSAACGYGFTLLSSKTKDVTKVWGMGLNKDSQLGFHRSRK-DKTRGYEYVLEPSPVPLP---LDRPQETKVLQVSCGRAHSLVLTDREGVFSMGNNSHGQCGRKVVEDEVYSESHKVHRMQD-----FDGQVVQVVCGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSTPSKLGGDLAGVTVVQVATYGDCCLALSADGGVFGWGNSEYLQLA-SVTDSTQVNVPRCLPFSG-VGKVKQVACGGTGCAVLNAEGHVFVWGYGILGKGPKLLETAIPEMIPPTLFGLTEFNPEVQVSQIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWR--VTMPGEPVDVACGVDHMVTLAKSFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96I51-1", "uniprot_id": "RCC1L_HUMAN", "id": "Q96I51-1", "name": "RCC1-like G exchanging factor-like protein", "aln": "MALVALVAGARLGRRLSGPGLGRGHWTAAGRSRSRREAAEAEAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFHRSRK-DKTRGYEYVLEPSPVSLP---LDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQD-----FDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLA-SVTDSTQVNVPRCLHFSG-VGKVRQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWR--VTMPGEPVDVACGVDHMVTLAKSFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPU0-1", "uniprot_id": "Q9VPU0_DROME", "id": "Q9VPU0-1", "name": "RCC1-like domain-containing protein", "aln": "---MLKTRGIVLGISRSYTAKAKRGVLAQDKSK-IKEYSPKTTDS-----------HEHRVYVWGFQETGALGLQTNVKKAKERYTEMVHHPTR------LQFSNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGFGILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFK--AAINGKVTKVAYGVDHTIALCKPFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .: . .:*: :* : :: : .**:****. :****: : * :. .. :* * ::. :::*:..*.*****: : : * .::* ***.******: . : :.. . : :: *:.: ** : :: :* .:*.**** :***:. :*::***::*****.::*:* **:* :**:.: :.:**** ******:***.**.:*:********** *:*: :. : :***: .::::: .** **:. *. ******** ** * .**:*:**.* :: :**:::.*.**: * ** :* *:.**:**** ** : ::: *: : *.*** .:*. * * * **: *:.*:...*:**:**** * **:*: :**:**:: :: * : :. *. ", "identical_positions": 162, "similar_positions": 152, "identity": "33.96%" }, { "cls_id": "homologset.agr.MGI:2137612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQF4-1", "uniprot_id": "FKBP6_RAT", "id": "D3ZQF4-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MSVFSRLRNGIPPSRDDCQSPYERLS----------QRMLDISG---------------------DRGVLKDIIREG--AGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLN-LSFVYLKLDRP--AMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XW8-1", "uniprot_id": "FKBP6_MOUSE", "id": "Q91XW8-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MGGSTRDPGALEGAGILGQSPYERLS----------QRMLDISG---------------------DRGVLKDIIREG--TGDTVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRKGELARFLFKPAYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLATCEEQHLVEPAVLLVLLN-LSFVYLKLDRP--AMALRYGEQALLIDKRNAKALFRCGQACLLLTEYERARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSRSSVGGN------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75344-1", "uniprot_id": "FKBP6_HUMAN", "id": "O75344-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MGGSALNQGVLEGDDAPGQSLYERLS----------QRMLDISG---------------------DRGVLKDVIREG--AGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLN-LSFTYLKLDRP--TIALCYGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMFAPCGDGSTAGES------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1I9-1", "uniprot_id": "FKBP6_DROME", "id": "Q9W1I9-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase shutdown", "aln": "MEENFEPYTPQLLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDGEELRSPWTYSFDELRALMSEIDENIYKRITRTGHVDREAVPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCPPRIKPKADALFKVEVIDYSLIGDAKGIDAIPQEDRDKF--CVVYPKAVDLHLHGKDSVKLGRYQSAATAFERAVSSLNYCRMANDEEERKQTELLTTLNQNLMIVYNKMNKPKRACIMMKALRHLTMGNPSCKALFQEGRALAALGEYNLARNAYLQAQAKQPANKEISDEIISMNKRISKYEEASRDIWARAFSLKNSKSDVRKTPAQLEKEAKEQDFNDKMEDLIRRFKNTSDQQVSFSRKSYSNAQFDATCKLAKEHNLKLTLSPIQEDVLTLSKPDVKFA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *. : * : **:.* *..: * : * * : *. .* * *:**** * ****. :* : ::: *:. .: *:*:.: *** * *.*::. :* ***** * *:: .**::*::*: .::. : *:. *::::* * *. : .*: .: .*: .* . ::**: *. :*:. :. * .* : * :.* *:::* : : . : * :.: ..****: *:* * **: **: ::** :** *::*.:*: .: . .* : .::: * *: .. * . . ", "identical_positions": 85, "similar_positions": 115, "identity": "18.6%" }, { "cls_id": "homologset.agr.MGI:2137617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQT5-1", "uniprot_id": "TINAL_RAT", "id": "Q9EQT5-1", "name": "Tubulointerstitial nephritis antigen-like", "aln": "MWGCPLGLLLLL-LAGQAALEARRSRWRRELAPGLHLRGIRDAGGRYCQEQDMCCRGRADECALPYLGATCYCDLFCNRTVSDCCPDFWDFCLGIPPPFPPVQGCMHAGRIYPIFGTYWENCNRCTCHEKGQWECDQEPCLVDPAMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMNEIYTVLGQGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHHQKGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQNDEASPTPRCMMHSRAMGRGKRQATSRCPNSQVDSNDIYQVTPVYRLASDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGINECDIETFVLGVWGRVGMEDMGHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JR5-1", "uniprot_id": "TINAL_MOUSE", "id": "Q99JR5-1", "name": "Tubulointerstitial nephritis antigen-like", "aln": "MWGCWLGLLLLL-LAGQAALEARRSRWRRELAPGLHLRGIRDAGGRYCQEQDMCCRGRADECALPYLGATCYCDLFCNRTVSDCCPDFWDFCLGIPPPFPPVQGCMHGGRIYPVFGTYWDNCNRCTCHEGGHWECDQEPCLVDPDMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSTVMNMNEIYTVLGQGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHHQQGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQN-EASPTPRCMMHSRAMGRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLGVWGRVGMEDMGHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZM7-1", "uniprot_id": "TINAL_HUMAN", "id": "Q9GZM7-1", "name": "Tubulointerstitial nephritis antigen-like", "aln": "MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERD-EAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * ******* ***: ** *::.* *************************:*******:******** ************************:******:*****.*****::****:*******:* :*:********** ******:*********************************:****:******. *****************************************************:************:*:**********************:********:: **.*:* ****************::***. *:.********.***.*::**************************: ********* ****:************************:*********** ************ ******:*****************", "identical_positions": 410, "similar_positions": 40, "identity": "87.61%" }, { "cls_id": "homologset.agr.MGI:2137624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3Z9-1", "uniprot_id": "PO121_MOUSE", "id": "Q8K3Z9-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGGREGRSRARGYGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRALSSFVRDARRHP-----------RPALTASPPPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALR---QDPRERPGRRPPARSPPP--------------ASAVQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSPRNSRMVCSPVTVRIAPPDSKLFRSSMSEQILDTTLSSPSSNAPDPCAKETVLNALKEK-KKRTVAEEDQLHLDGQENKRRRHDSGGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLASA-CTGGIPSSSRNAITSSYSSTRGISQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCQQSSS---SPPLVTDKESPGEKVTDTTTGKQQSSWTSPPTPGSSG-QRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERKASLQWFNKVLEDKPDDASASATDGPPSTSPPFTFTLPAVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPAEAATVAAPSPPKTPSLLAPLVSPLAGP---LASTSSDSKPAATFLGLASASSITPLTDSKSSGVSQAEQSVSTPASTASSPTPKPSMLFGMLSPPASSSSLATPAPACASPMFKPIFPATPKSESDSPLPSSSSAATTASSSTAPPTAASTTP-TFKPIFDK-MEPFTAMPLSTPFSLKQTTATATTTATSAPLFTGLGTATSTVASGTAAS-----ASKPVFGFGVTTAAS----TASSTMTSTSQSVLFGGAPPVTTSSSAPALASIFQFGKPLAPAASAAGTSFSQPLASSTQTAASNS--GFSGFGSTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSSSAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAPA------------------TFGSAAQPAFGGLKAAASTFGAPASTQPAFGSTTSVFSFGSATTSGFGAAATAATTTQTTNSGSSSSLFGSSAPSPFTFGGSAAPAGSGGFGLS-ATPGTSSTSG-TFSFGSGQSG--TPGTTTSFG-SLSQNTLGAPSQGSPFAFSVGSTPESKPVFGG---TSTPTFGQSAPAPGVGTTGSSLSFGASSTP---AQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52591-1", "uniprot_id": "PO121_RAT", "id": "P52591-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRGLSSFVRESRRHP-----------RPALTASPLPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALP---QDPRDRPGRRPPSRSPPS--------------SSTAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLFRSPMPEQILSTTLSSPSSNAPDPCAKETVLNALKEK-KKRTVAEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTST-CTGGIPSSSRNAITSSYSSTRGVSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCHQSSS---SAPLVTDKESPGEKVTDPATGKQQSLWTSPPTPGSSG-QRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERRASLQWFNKVLEDKTDDASTPATDTSPATSPPFTLTLPTVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPPEAATVAAPSPPKTPSLLAPLVSPLTGP---LASTSSDSKPTTTFLGLASASSATPLTDTKAPGVSQAQLCVSTPAATAPSPTP-ASTLFGMLSPPASSSSLATPGPACASPMFKPIFPATPKSESDNPLPTSSSAATTTPASTALPTTATATAHTFKPIFES-VEPFAAMPLSPPFSLKQTTAPATTAATSAPLLTGLGTATSTVATGTTAS-----ASKPVFGFGVTTAAS----TAS-TIASTSQSILFGGAPPVTASSSAPALASIFQFGKPLAPAASVAGTSFSQSLASSAQTAASNSSGGFSGFGGTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSASAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAPA------------------AFGGAAQPAFGGLKASASTFGTPASTQPAFGSTTSVFSFGSATTSGFGAAA---ATTQTTHSGSSSSLFGSSTPSPFTFGGSAAPAGGGGFGLS-ATPGTGSTSG-TFSFGSGQSG--TTGTTTSFGGSLSQNTLGAPSQSSPFAFSVGSTPESKPVFGG---TSTPTFGQSAPAPGVGTTGSSLSFGAPSTP---AQGFVGVGPFGSGAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96HA1-1", "uniprot_id": "P121A_HUMAN", "id": "Q96HA1-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAAGAGERRRPIASVRDGRG--RGCGGPARAVLLGLSLVGLLLYLVPAAAALAWLTVGATAAWWGLSREPRGSRPLSSFVRKARHRRPLSSFVRKARHRRTLFASP-LAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAAAPEGQDLRDRPGRRPPARPAPRSPPPRSPPPRSPPPSPPTHRAHHVYPSLPTPLLRPSRRPSPRDCGTLPNRFVITPRRRYPIHQAQYSCLGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKEKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGA-YASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSS---STPLAADRESQGEKAADTTPRKKQN-SNSQSTPGSSG-QRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS-MGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATS--APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPA--AAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVF-FGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTG-AFSFGAGQSG--STATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGG---TATPTFGLNTPAPGVGTSGSSLSFGASSAP---AQGFVGVAPFGSAALSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NF01-1", "uniprot_id": "P121B_HUMAN", "id": "A6NF01-1", "name": "Putative nuclear envelope pore membrane protein POM 121B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRVRTS---------------------------------ELWKRNGPSSSPFSSPASSRSQTPERPAKKIREEEMCHHSSS---STPLAADKESQGEKAADTTPRKKQN-SNSQSTPGSSG-QRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSS-MGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS--APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPA--AAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTG-AFSFGAGQSG--STATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGG---TATPTFGLNTPAPGVGTSGSSLSFGASSAP---AQGFVGVAPFGSAAPSFSIGAGSKTLGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8CG34-1", "uniprot_id": "P121C_HUMAN", "id": "A8CG34-1", "name": "Nuclear envelope pore membrane protein POM 121C", "aln": "MSPAAAAAGAGERRRPIASVRDGRG--RGCGGPAGAALLGLSLVGLLLYLVPAAAALAWLAVGTTAAWWGLSREPRGSRPLSSFVQKARHR-------------RTLFASP-PAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAPAPEGQDLRNRPGRRPPARPAPRSTPP----------SQPTHRVHHFYPSLPTPLLRPSGRPSPRDRGTLPDRFVITPRRRYPIHQTQYSCPGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGA-YTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSS---STPLAADKESQGEKAADTTPRKKQN-SNSQSTPGSSG-QRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSASPMFKPIFTAPPKSEKEGLTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSS-MGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS--APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTG-AFSFGAGQSG--STATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGG---TATPTFGQNTPAPGVGTSGSSLSFGASSAP---AQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R543-1", "uniprot_id": "F1R543_DANRE", "id": "F1R543-1", "name": "", "aln": "------MSPEDKRRLVVFS----------------AVVFSLFILLLVLSYIPAYLYILFICVVSCVVYFHKAEELQLFERLGLNPRRGLSVPP-----ALLRWLPGRTFSGVPAAGRNKIRKSDARTSFAS--PSDRHFVGSYYRREQLSESVFSPRDILMGSYLAKPEESPSAAVRPAGGS-----GSFMHPREQLRERLARPNHAVHTPNRRLSFGDPAGNASRFTITPQRHYPLQQTGTSPIGVMPPAKWDGYRKKNILTQRNSPTVHSPVTVKIARPDSTRSSFFNHLNSPGAVTSPGIGAQADPCSREAVLSVLRES-RKREVDEEDKSASSGQKSKRRRHDSSGSSQSAFEPLLANGAPSQLVPKPGSLKRGMNSSLIEESIMKRSRTSSVSSISGAPVPSGVPGSVRNPIRSSYSSSQGYPQRRAASSLSLSPFTSPGGSRCQTPERAAKKAREEDATSPSSTSFAKTDKVAADPDPSPNTTKLTPKSEAPVATSTSDSGSSGGKRKRKIQLVTTNRGDQISLPPPPEVGYTITVKDLDMEKKAALSKIQKVLEEPEPEIPPPASEPAP---------APVSAPTLSLFSQPAP-----------ISTSGTAPATSVVPSLLSLSTPKPETTPAITTTPAPTIDLTITASSTASSAPLTLISSPAITTASLTAATTVSTAPASSISNPLLESLKNMKNNPLLTAPTLMGTTT-----AAPAVPVSSLSAPAASIIPSSGVVKSESGPTALQSSFSAPSSISSPAFKPATSMPSTFAQILAQPLQPPSTISSLGGGSSLFSLIKPVATPASEPPKSTVAAPTNTAASVNSISNPLSSGFKPIFSAASTTPAS----TPEVKPTQPTFKPLFG---STTISGVSAFGQTITPTTSTPAAPASQNSAMLFGGLTSTQPTTVPSSAAPATQTPSQSLFGKWSTPTTSAPATNPTFQFGATSTTTATPALNTNTASVGSANSAFQFG--------AAKPAAAPQAQNTFTFGQQSTNQNSTTTPFGGFG-------VTSNATTSSEAPTTQTTFGSSTFTTSSNFPASTPQALAAPKPFAFGAAGASSGASPFTFGTAASTSAPAFGTNSQPAFGGVSSGFSFGNTTTPSATPVFGATTQTAAPAPAPAPTFTFGGAPTANQNTAPSTPAPPASGGFNFGASLSSTPFGTPAPAAQPQGFSFGANNTDSKPAFGTSTPAFGQASPGMSMPFGSPGTPGFGAMGGLGASPFGASPASFSIGTGTKTSGARR-LQARRQHPRKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* *:* : .. : ***:**..**.*****.*** ***: **: .. .: . . :.:. :. .: .* . .**** :****:**:.:.**:*::*****::**:**.:***:*::*:*. :::.**: . ..:: .* *. ..: . * ** :. . *. . . : : .* .** : .. . . .:.* . . : .: .*. .. * :.:. :: .. .* . *:* . :: *.* .: :.* . * .: ..... . .* ::.:. *:. ..::: . ** :: . : * :::. : ..:..:: * : :.:.*.:.*. .: * . ** *. . .: :* *. . : .: *** .: :. :. :* .. * .:: : : * :: *:...* : . . :..*:* *: . : .* . . .: :. .: .**. ** *:*** :*. .:****:. : ::.. . . :::.:** . ::*: ..::.*. . .. .* ..*::.. : .:. *:.*. . ..* *:**.:::*:. ** . *.....:.. :*:**.. :. ....:*. . . :*:. ..:**. . :: . **. :.*:** .:** * .:.* *:.**:..:* * * :*..***:.. *****:*:** ***: *******.***", "identical_positions": 175, "similar_positions": 329, "identity": "13.63%" }, { "cls_id": "homologset.agr.MGI:2137630", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6G8-1", "uniprot_id": "G3V6G8_RAT", "id": "G3V6G8-1", "name": "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPGGLSRSLPPRPPAKGSIPVSRLFPPRTPGWQQPQPRRVSFLCETSETLQSPGYDPSRPESFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMS----PFRGPKDRTRKLAEVGGHEKVG--QHPHCVRLERAWEEGGILYLQTELCGPS-----LQQHCEAWGASLPEAQVWGYLRDTLLALDHLHSQG-LVHLDVKPANIFLGPRG-RCKLGDFGLLVELGSAGAGEAQEGDPRYMAPELLRG-SYGTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLTMMLEPDPQLRATAEVLLALPMLRQP-RPWNVLWYMAAEALSRGWALWQALVTLLCWLWHGLVHPASWLQPPGPPATPPGSPPCSPLLDSTLSSNWDDDSIGPSLSPETILSR-ITRRTSTPRGRYTPRDVLDLTDMDSE--PPRGPCPTFEPRNLLSLFEDSLDPA----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESG9-1", "uniprot_id": "PMYT1_MOUSE", "id": "Q9ESG9-1", "name": "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPGGLSRSLPPRPPAKGCIPVSRLFPPRTPGWHQPQPRRVSFLCETSEPLQSPGYDPSRPESFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMS----PFRGPKDRTRKLAEVGGHEKVG--QHPHCVRLERAWEEGGILYLQTELCGPS-----LQQHCEAWGASLPEAQVWGYLRDILLALDHLHSQG-LVHLDVKPANIFLGPRG-RCKLGDFGLLVELGSAGAGEAQEGDPRYMAPELLQG-SYGTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLAMMLEPDPQLRATAEALLALPMLRQP-RPWNVLWYMAAEALSRGWALWQALVTLLCWLWHGLVHPASWLQPPGPPATPPGSPPCSPLLDSTLSSSWDNDSIGPSLSPETVLSR-ITRRTSTPRGRYIPRDALDLTDVDSE--PPRGPCPTFEPRNLLSLFEDSLDPA----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99640-1", "uniprot_id": "PMYT1_HUMAN", "id": "Q99640-1", "name": "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGSIPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMS----PFRGPKDRARKLAEVGSHEKVG--QHPCCVRLEQAWEEGGILYLQTELCGPS-----LQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQG-LVHLDVKPANIFLGPRG-RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQG-SYGTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLRQP-RAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCSLLLDSSLSSNWDDDSLGPSLSPEAVLAR-TVGSTSTPRSRCTPRDALDLSDINSE--PPRGSFPSFEPRNLLSLFEDTLDPT----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NI63-1", "uniprot_id": "PMYT1_DROME", "id": "Q9NI63-1", "name": "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKHHRLPLPELHDDKHRHKQCNGENSNRFRPPKYKTRGYVAVDNNNLNRSQSLGSCSTNSSQIAHAISFRDAGCSDSSTLPSSPVQAELSTLS---------LSHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQ----LFRGEQYRAERLEEVRRYEEFS--GHENCIRFIRAWEQYDRLYMQMELCRES-----LEQYLLRCQR-IPEERIWHILLDLLRGLKSLHDRN-LIHLDIKLDNVLIGEDDETCKLADFGLVIDVDRANSHHATEGDSRYMAPEILQG-HFSKAADIFSLGIAMLELACYMDLPSNGPLWHELRHGILPEEFINKISLELQSVIKSMMKPDPAQRPTAEQLLSHPKLQYLQKKRKSLMNFSMLSRSFRRSRRAVWGRMCNWKTAAFRYLLYFLEVLHLCKPITASQPNINIVPSSPSS--KGVPLVPQVEFQLVGSTPIANRDCYASDFLSGEDPLDLSNQGSPNVINSTPLNTNQGKSRLDLLKNNVDSMGRYVHVHDFESPCSALSSAKVLDTSSFRRKKLFVLEYDDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32944-1", "uniprot_id": "SWE1_YEAST", "id": "P32944-1", "name": "Mitosis inhibitor protein kinase SWE1", "aln": "MSSLDEDEEDFEMLDTENLQFMGKKMFGKQAGEDESDDFAIGGSTPTNKLKFYPYSNNKLTRSTGTLNLSLSNTALSEANSKFLGKIEEEEEEEEEGKDEESVDSRIKRWSPFHENESVTTPITKRSAEKTNSPISLKQWNQRWFPKNDARTENTSSSSSYSVAKPNQSAFTSSGLVSKMSMDTSLYPAKLRIPETPVKKSPLVEGRDHKHVHLSSSKNASSSLSVSPLNFVEDNNLQEDLLFSDSPSSKALPSIHVPTIDSSPLSEAKYHAHDRHNNQTNILSPTNSLVTNSSPQTLHSNKFKKIKRARNSVILKNRELTNSLQQFKDDLYGTDENFPPPIIISSHHSTRKNPQPYQFRGRYDNDTDEEISTPTRRKSIIGATSQTHRESRPLSLSSAIVTNTTSAETHSISSTDSSPLNSKRRLISSNKLSANPDSHLFEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEG-NLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVLPDNGNAWHKLRSGDLSDAGRLSSTDIHSESLFSDIT-----KVDTNDLFDFERDNISGNSNNAGTSTVHNNSNINNPNMNNGNDNNNVNTAATKNRLILHKSSKIPAWVP-----KFLIDGESLERIVRWMIEPNYERRPTANQILQTEECLYVEMTRNAGAIIQED-------------DFGPKPKFFI------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. : : : .. .. . . * * *.: : * .: :*.*.:. *::* . .: **:* :: . . * ** .. : : :*: . *: *** . *:: : : ::* : : .* :*. ::***:* *::: . **.***: .: . *** .*:***:: . :. **:****: ::*:*. : ** .* *::** * *. : . : : : :: *: . . . . . : . :: . . : *. . . . . : : : : : ", "identical_positions": 58, "similar_positions": 113, "identity": "6.51%" }, { "cls_id": "homologset.agr.MGI:2137642", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ38-1", "uniprot_id": "D3ZZ38_RAT", "id": "D3ZZ38-1", "name": "Sorting nexin", "aln": "MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGINSRGDRGLFPASYVQVIRAPEPGPPADGGPGAPARYANVPPGGFEPLPAAPPAAFQP-------LLQPQASP--GSFQSPGAGFTYGGGAPQPSPQQLYGAYQASLGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGGGAAGRYRLSTRSDLSLGSRGVSAPPPHQASGAKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKG---ALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKYDSV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZR2-1", "uniprot_id": "SNX18_MOUSE", "id": "Q91ZR2-1", "name": "Sorting nexin-18", "aln": "MALRARALYDFKSENPGEISLREHEVLSLCSEQDIEGWLEGINSRGDRGLFPASYVQVIRAPEPGPPADGGPGAPARYANVPPGGFEPLPAAPPAAFPP-------LLQPQASP--GSFQPPGAGFPYGGGALQPSPQQLYGGYQASLGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGGGAAGRYRLSTRSDLSLGSRGVSAPPAPSVWSQELGHGEPQ-PQSLLHLRQVGRGGLRAGRGVRLREGWGQAVRGAGSYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKG---ALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKYDSV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RF0-1", "uniprot_id": "SNX18_HUMAN", "id": "Q96RF0-1", "name": "Sorting nexin-18", "aln": "MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQPPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLECK-LDCSTGSFLLEYLALGNEYSFSKVQRVPLMTVLSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMM5-1", "uniprot_id": "A5PMM5_DANRE", "id": "A5PMM5-1", "name": "Sorting nexin", "aln": "MALRARALYDFNSENPGEISVKENEIVTLYSEQDIEGWLEGTNSRGARGLLPASYVEILRNDTVSSFNNN-----SRYANVPTGAFESFNSTPASTFSA--------------------------YP-----ALPQQQQQQQPHQGTPASDDDWDDDWDDHSSIADEPGVVG-GGYRNYEGNGPSG------YSISTSS----MPRG--------AQQAKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKICVVMGQYGPEWQENPYPFSCTIDDPTKQTKFKGMKSYISYKLTPTHTQSQVNRRYKHFDWLYARLVEKFPVISVPHIPEKQATGRFEEDFISKRRRGLIWWMNHMTSHPVLARCDVFQHFLSC-SSTDEKAWKQGKRKAEKDEMVGANFFLTISTPP-APLDLQDVESRIDGFKVFSKKMDDSVIQVNATLSEFARKQIAGFKKEYQKVGQSFKYLSQAFEMDQQSYSIGLNQAIAYTGEAYEVIGDYFVEQPKQDVDPVMDLLALYQGHLTNYPDIIHVQKG---ALTKVKESQKHVEEGKMESQHADGIRDRCNIISFATMAEIQYFHQTRVRDFKSQMQHFLQQQISFFQKVTGKLEEALQKYDNA--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********.********::*:*:::* *********** **** ***:*****:::* .. :. :******.*.**.: :*.::* . :. *. ** :*.: .*******:*** *::*****.:* *.* : :*...:* * :** * .** : . .: : : : : * .: *.. : :. .: * ************.***********************.***** *:*************.**********:******************:*********:******:********:* ****************************:**** *.****:***:***** *:******.:*:* * .******::*************: ******:***::*:*******:**:**:.**: *.***:**:**************:*:********* .* :* * :* . : : . . *: ... . : :... ** : : : :: : . : : ", "identical_positions": 331, "similar_positions": 125, "identity": "52.62%" }, { "cls_id": "homologset.agr.MGI:2137648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VCK2-1", "uniprot_id": "GILT3_DROME", "id": "Q9VCK2-1", "name": "GILT-like protein 3", "aln": "---MNKIFGLLFTLCLLLVWP---TPGNGQS------------------------------PDESRLLVAIHYEALCPDSMSFIRRRLYDALQDNDWWSVTDLKLYPFGKAGFYNNTSTGESQVFCQHGVDECELNALHACIIETLDIRKAFNLIYCMLR--SYSNELGPCSRSMGVDVS---------------KARECKASRTTAEILAPYGKETLKLG--ISFVPTIVFENDFDPYDQRSIRNNFERHFCRQY-----------LKKFNIKLPTCSAIL-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCK1-1", "uniprot_id": "GILT2_DROME", "id": "Q9VCK1-1", "name": "GILT-like protein 2", "aln": "-------MRAAVFVCLLLGWVGVATPRRLRG------------------------------PQADRLAITLYYEALCPYCMEFVTTQLNPSMVRQDRLPFTDLTLVPYG-----NARTNDDGNVECQHGVMECELNAWHACILEHHDIAQSLKLIACMMR--GKKNRLEKCADHYQIDVG---------------DVKNCKKTRQVNDILRKYGKETAKVS--FQGVPAVALDNVYNADLSANLTDHFDAIFCAKY-----------KEKFNKQLNNCQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q499T2-1", "uniprot_id": "GILT_RAT", "id": "Q499T2-1", "name": "Gamma-interferon-inducible lysosomal thiol reductase", "aln": "----MSCSPLVPFLSLLLLLFLPEVPRAATASLPQGSSEG----AATCKAHDLCLFGPRRLLSAPPVNVSLYYESLCGACRYFLVRNLFPTWLMV--MEIMNITLVPYGNAQ--ERNVSGTWEFTCQHGELECKLNKVEACLLDKLEKEAAFLTIVCMEEMEDMEKKLGPCLQLYVPEVSP-------------ESIMECATGKRGTELMHENAQLTDALQPPHEYVPWVLVNEKP---LTDPSQ--LLSSVCELY-----------QGTEKPDICSS-MADAPREVCYK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESY9-1", "uniprot_id": "GILT_MOUSE", "id": "Q9ESY9-1", "name": "Gamma-interferon-inducible lysosomal thiol reductase", "aln": "----MSWSPILPFLSLLLLLFPLEVPRAATASLSQASSEG----TTTCKAHDVCLLGPRPLPPSPPVRVSLYYESLCGACRYFLVRDLFPTWLMV--MEIMNITLVPYGNAQ--ERNVSGTWEFTCQHGELECRLNMVEACLLDKLEKEAAFLTIVCMEEMDDMEKKLGPCLQVYAPEVSP-------------ESIMECATGKRGTQLMHENAQLTDALHPPHEYVPWVLVNEKP---LKDPSE--LLSIVCQLY-----------QGTEKPDICSS-IADSPRKVCYK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13284-1", "uniprot_id": "GILT_HUMAN", "id": "P13284-1", "name": "Gamma-interferon-inducible lysosomal thiol reductase", "aln": "----MTLSPLLLFLPPLLLLLDVPTAAVQASPLQALDFFGN-GPPVNYKTGNLYLRGPLKKSNAPLVNVTLYYEALCGGCRAFLIRELFPTWLLV--MEILNVTLVPYGNAQ--EQNVSGRWEFKCQHGEEECKFNKVEACVLDELDMELAFLTIVCMEEFEDMERSLPLCLQLYAPGLSP-------------DTIMECAMGDRGMQLMHANAQRTDALQPPHEYVPWVTVNGKP---LEDQTQ--LLTLVCQLY-----------QGK-KPDVCPS-STSSLRSVCFK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJN2-1", "uniprot_id": "GILT_DANRE", "id": "Q5XJN2-1", "name": "Gamma-interferon-inducible lysosomal thiol reductase", "aln": "----MFGFNLCVVLVAVFSLSKCSARFVYSCKYPPSQWCSSEDIAAECGVLEQCMKYN-STKAADKVKVSLYYESLCPGCRMFLTSQLVPTLIML--QDIMEIDLVPYGNAQ--ETQAQGKYIFTCQHGEDECLGNMIETCMLNKLGLD-AVMVIFCMESGNDVLKSAQPCLGVYRPDVTW-------------DSIMQCVKGDQGNKLMHENAVKTDALNPPHQYVPWITVNGEHTDDLQDKAMGSLFSLVCSLY-----------KGQ-KPAACTLGLKKNTNNYCMN-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0C4DHN2-1", "uniprot_id": "A0A0C4DHN2_DROME", "id": "A0A0C4DHN2-1", "name": "Gamma-interferon-inducible lysosomal thiol reductase", "aln": "MISVRNRIHIRLFVVVALVCLFIVVLWYYPVPVLTSQLHG---------------------GALMKVVVTVYYEALCPDSKYFLTKQLLPTFKIA--KSIMEVKLAPYGKAK--TKEHNGKITFDCQHGPIECQANIYHACAAEIIEDPLLRLEVATCMIMDNHSPQEAMNKCTSQINFDD-------------SVIQNCFESYRGVDLLKVIGESTNSLRPPITFIPTITIDGSQG--RQESILKDLLSEVCKAAG----------DSREVKDICKI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHA5-1", "uniprot_id": "Q9VHA5_DROME", "id": "Q9VHA5-1", "name": "GILT-like protein F37H8.5", "aln": "-MTKLASTASLLLLVLSLGWAKLEEKPREKR-------------------------------QSNKLHITLLYESLCPDSRNFMH-QLGPVYEEFG--DYIDILLVPFGKSQ----SERNGAIFHCQHGPAECKGNRLQSCVINSTANQAAQVKFVVCQMLAPDYSRIDQCANEAGLLTD----------------VVHCLSSETGTKLQLQAELVTKQYSP--SFIPTIVYNGVFDQQLQDHSLRDFRGTVCYMLR----------QQNLLPSSSTICQ---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q95RA9-1", "uniprot_id": "GILT1_DROME", "id": "Q95RA9-1", "name": "GILT-like protein 1", "aln": "------MSHKIAAVCLLMSCLIATAYS------------------------------------AAKVPISIYYESLCPDSAKFITEQVYPAVKGEL-RDVVELTFVPFGKSQ--FVTQGSEVTFTCHHGPNECYGNKVHACAIEHIQANSYQVEYTRESLTMDFINCLMKAGKNFPDNVYPGQRCASENHINNWENIKTCANSTEGSVLLRKAGESTMRLKEPLTSVPTILFNEQFDKKVNDRAQVNLVGTICQYVSAPQPRICNQHNGASTPSLASVSAILSSLLGLWFIRSFY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::: **:** . *: : :: : *:* . . *:** ** * .:* : * : * :* : : : .* ", "identical_positions": 18, "similar_positions": 26, "identity": "6.1%" }, { "cls_id": "homologset.agr.MGI:2137668", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LG51-1", "uniprot_id": "A0ABK0LG51_RAT", "id": "A0ABK0LG51-1", "name": "Zinc finger homeobox protein 4", "aln": "METCDSPPISRQENGQSTSKLCGTTQLDNEVPEKVAGMEPDRENSSSHDNLKTEEHERKSEVLLGFSIENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPVLKDD-ESETSELEDSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSKLFSTAMFLDSLASVGEKSDQSASGPVSFYPQIINTFHIASSLGKPFTADPAFPNTSALAGVGPVLHSFRVYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVTDGKRKPVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQRLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTFRGLWS--AFHVENGDSLPAGFAFLKGSASPSSSAEQPLGITQMPKAEVNLGGLSSLVVNTPITSVSLSHSSSESSKMSESKDQENNCERPKENTVLHPNGECPIKSEPNEPGDEDEEDAYSNELDDEEVG-ELTDSIGNKDFPLLNQSISPLSSSVLKFIEKGTSSSSSGTSADDAEKKTQAAAAAAAGRNSGNVTNSYGIGGKDFADGSVSRDGATAAHPSETTRGDEDSSMTSHQHGFTPSTPGTPGPGGDGSPGNGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPAP----------------------------------NTSLSGCGTPSPS----------------KPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLG------------------LAPAEAELYQYYLAQNIGLTGTKLENPADPQLLINPFQLDSATAAALAPGLVNNELPPEIRLASGQLMGDDLSLLTAGELSPYISDP----------ALKLFQCAVCNKFTSDSLEALSVHVNSDRS----LPEEDWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKTNEWRLKCIA---IGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQ-------KQESAVNSESCYYYCAVCDYSSKIKLNLVQHLRSVKHQQTEGLRKLQLHQQGLPPEEDNLSEIFFVKDCPANELETASLGARTGVDELTEQQLRTASEELSEDAGGALKPTTVTEDDEKETQERDNSEGKVSNNDPGVITPEKELKVAVAGATQPLLLAKEDDTGTKRSKPTEDNKFCPEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVSP--DCVEKLLMTVPVPDVMMPNSMLLPATTPEKSERDPPTAMAAAGSGKYSGDSPVDDKSMSGLEDSKVGVEIKNEEQKPAKEPIETSEWSKNSSRDANISDALQDQLSEQQ----KRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAELQHLYASLPMNGELWAEGETMPQEDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDLGSEPKRTLPFRKGPNFTMEKFLDP--SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVPQEANSSTDNKPYKCSICSVAYSQSSTLEIHMRSVLHQTKARAAKLEPSRHLSSGHSITAAVNS---PGQGMLESMSLAPVNS-KDTHLDAKELNKKQTPEIITAQPTHHPPPRSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGAEFSLGPDLALPSSTTFGMPGMTTGMAGSLLEDLKQQIQTQHHVGQTQLQLLQQQAQQYQAAQPQLQPPNQQP-PPPPQQQPQQPPSKLLKQEQGSLANTDCQLMKDAPSYKEAEEMTEKEE-KPKQESTNDTDGLKDSKDVKKQKSLEPCIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENSEKLECGTCGKLFSNVLILKSHQEHVHGQFFPYGALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSALGPVKIPNTVSAPLQAPPPTPPPPPPPPPPPPPPPPPPP-SAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDTLSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDASFS--KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAEAKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVLYKPCTVSGQTDTAKSTAAPVASSGSGTSTPLIPSPKPEPEKNSPKPEYPAEKTKQNDPSLP-QGIKSAPSSVSTSSEPQQASISQPPPQL--PKQPQLIGRPPSASQTPIPSSPLQISMTSIQNSLPPQLLQYPCDQCTIAFPTLELWKEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASTAHTTAPASVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSSENELASTVSTPVSKTAELSPKNLLSPSSFKAECPEDVENLNAPSADAGYDQNKTDFDETSSINTAISDATTGDEGAADMEN-TGGSEEVKPALSPKETKSLDSLPKAGTTPTTEVCDDKFLFSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSK--SSDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQSGTDGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGITDNCSLHGISLPAAYPGLPGLPPVILPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPSSATSSPALSLSSAPTKSLLQTPPPPPPP-PPPPPPPPSSLSGQQTEPQNKEPEKKQTKPNKVKKIKEEESEAIKPEK-HPKKEEKISSALSVLGKVVGETHMDPTQLQALQNAIAGDPTSFIGGQFLPYFIPGFASYFTPQLPGTVQGGYLPPVCGMESLFPYGPAVPQTLAGLSPGALLQQYQQYQQSLQDSLQKQQKQQQEQQQK-------PVPAKTAKGEGDQPQSSNEASETKEEKSTAPESTKEEAQLDSKTTEFSDTCVVPFVKYEFICRKCQMMFTDEDATVNHQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDLALSGNEALSQHLQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPPPNTSSTSPSAASSNNTYPHLSCFSMKSWPNILFQASARKAASSPSS-PPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQKLQDLDNSLEVKAKPASGLDGNFSSVRMDMFSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJN2-1", "uniprot_id": "ZFHX4_MOUSE", "id": "Q9JJN2-1", "name": "Zinc finger homeobox protein 4", "aln": "METCDSPPISRQENGQSTSKLCGMTQLDNEVPEKVAGIEPDRENSSSHDNLKTDE--RKSEVLLGFSIENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPVLKDD-ESETSELEDSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSKLFSTAMFLDSLASAGEKSDQSSTAPVSFYPQIINTFHIASSLGKPFTADPAFPNTSALAGVGPVLHSFRVYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNDEERRLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPNFSTTNLIGPDPTFRGLWS--AFHVENGDSLQAGFAFLKGSASPSSSAEQPLGITHMPKAEVNLGGLSSLVVNTPITSVSLSHLSSESSKMSESKDQENNCERPKESTILHPNVGCPVKSEPTEPGDEDEEDAYSNELDDEEVLGELTDSIGNKDFPLLNQSISPLSSSVLKFIEKGTSSSS-GTIAEDTEKKKQ---AAATGRSNGNVTNSYSIGGKDFADGSISRDGTTAA-PSETTHGDEDSSTT-HQHGFTPSTPGTPGPGGDGSPGNGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKTGQPHPRLARGESYTRGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPTP----------------------------------NTSLSGCGTPSPS----------------KPKQKPTRRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLG------------------LAPAEAELYQYYLAQNIGLTGMKLENPAETQLLLNPFQFDSATAAALAPGLG--------------------------ELSPYISDP----------ALKLFQCAVCNKFTSDSLEALSVHVNSERS----LPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIA---IGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQ-------KQEGAVNSESCCYYCAVCDYSSKIKLNLVQHVRSVKHQQTEGLRKLQLHQQGLPSEEDNLSEIFFVKECPANELETASLGARNGEDELIEQQLKAASEEPSEDAGDPLKPPTVAEDDEKEAHKRDNSEGKISTKDPEVIVPEKEPKVVTG-ATQPLLLAKEDSTGTKRSKPTEDNKFCPEQFYQYPCCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVSP--DCVEKLLMTVPVPDVMMLNSMLLPAAAPEKSEQDPPTALTAEGSGKCSGDGPVDDKSMSGLEDSKVGVEIKNEEQKPAKEPVEASEWNKTSSKDVNISDALQDQLNEQQ----KRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCTLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPMNGELWAESETMTQDDHGIDQEMEREYEVDHEGKASPVESDGSSIPDDLGLEPKRTLPFRKGPNFTMEKFLDP--SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVPQEANSSTDNKPYKCSTCSVAYSQSSTLEIHMRSVLHQTKARAAKLEPSRHLPSGHSITAAVNS---PGQGMLESMSLASVNS-KDTHLDAKELNKKQTPELISAQPTHHPPPRSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGAEFSLGPDLGLPTSTTFGVPGMT-GMAGSLLEDLKQQIQTQHHVGQTQLQFLQQ-AQQYQAVQPQLQPQNQQP-PLPQQQQPQQQPSKLLKQEQGSLASTDCQLMKDMPSYKEAEEVTEKQE-KPKQEFINDTEGLKDSKDIKKQKSLEPCIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENSDKLECGICGKLFSNVLILKSHQEHVHGQFFPYGALEKFARQYREAYDKLIQF------------LLPPLPPAPPQPSTLGPVKIPNTVSAPLQAPPPTPP------------------SAPQQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDTLSADLTQLCQQQLGIDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVVKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDAAFS--KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAEAKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVLYKHCMVSGQTDTAKSTATLVASSGSGTSTPLIPSPKPEPEKNSPKTEYPGEKTKQSDPSLP-QGTKSAPSSVLTSSEPQQASIPQPPTQP--PKQPQLIGRPPSASQTPIPSSPLQISMTSLQNSLPPQLLQYPCDQCTLAFPTLELWKEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQTSTAHTTAPASVAASLKRKLEDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSTENELASTVSTPVSKTAELSPKNLLSPSSFKAECPEDVENLNAPSADAGYDQSKTDFDETSSINTAISDATTGDEGAADMEN-TGGSGEVKPALSPKETKTLDSLQKPATTPTTEVCDDKFLFSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSK--SNDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKERKFKINIGKPFMINQSGTDGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQQGITDNCSLHGISLQAAYPGLPGLPPVILPGMNGPSSLPGFPQNSNTLTSPGTGMLGFPSSATSSPALSLSSGPTKSLLQTPPPPPPP-PPPP----SSLSGQQTEPQNKESEKKQTKPNKVKKIKEEESEAIKPEK-HPKKEEKISSALTVLGKVVGETHMDPTQLQALQNAIAGDPASFIGGQFLPYFIPGFASYFSPQLPGTVQGGYLPPICGVESLFPYGPAVPQTLAGLSPGALLQQYQQYQQSLQDSLQKQQKQQQEQQQK-------PVPAKTAKGEGDQPQSSNEASETKEEKSTAPESTKEEVQLDSKSAEFSDTCIVPFVKYEFVCRKCQMMFTDEDATVNHQKSFCYFGQPLIDPQETVLRIPVSKYQCLACDLALSGNEALSQHLQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPPPNTSSTSPSAASSNNTYPHLSCFSMKSWPNILFQASARKAASSPSS-PPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQKLQDLDNSLEVKAKPASGLDGNFNSVRMDMFSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UP3-1", "uniprot_id": "ZFHX4_HUMAN", "id": "Q86UP3-1", "name": "Zinc finger homeobox protein 4", "aln": "METCDSPPISRQENGQSTSKLCGTTQLDNEVPEKVAGMEPDRENSSTDDNLKTDE--RKSEALLGFSVENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPVLKDDNESEISELEDSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSKLFSTAMFLDSLASAGEKSDQSASAPMSFYPQIINTFHIASSLGKPFTADQAFPNTSALAGVGPVLHSFRVYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTFRGLWS--AFHVENGDSLPAGFAFLKGSASTSSSAEQPLGITQMPKAEVNLGGLSSLVVNTPITSVSLSHSSSESSKMSESKDQENNCERPKESNVLHPNGECPVKSEPTEPGDEDEEDAYSNELDDEEVLGELTDSIGNKDFPLLNQSISPLSSSVLKFIEKGTSSSS-ATVSDDTEKKKQ----TAAVRASGSVASNYGISGKDFADASASKDSATAAHPSEIARGDEDSSATPHQHGFTPSTPGTPGPGGDGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPAP----------------------------------NTSLSGCGTPSPS----------------KPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLG------------------LAPAEAELYQYYLAQNIGLTGMKLENPADPQLMINPFQLDPATAAALAPGLG--------------------------ELSPYISDP----------ALKLFQCAVCNKFTSDSLEALSVHVSSERS----LPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIA---IGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQ-------KQEGAVNPESCYYYCAVCDYTTKVKLNLVQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDLTEQH---------EEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDS----------VSVAGGTQPLLLAKEEDVATKRSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVSP--DCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGESPMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQ----KRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFTMEKFLDP--SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS---PGQGMLDSMSLAAVNS-KDTHLDAKELNKKQTPDLISAQPAHHPP-QSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSATFGMPGMT-GMAGSLLEDLKQQIQTQHHVGQTQLQILQQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPE-KPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDASFS--KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSSENELASTVSTPVSKTAELSPKNLLSPSSFKAECSEDVENLNAPPAEAGYDQNKTDFDETSSINTAISDATTGDEGNTEMESTTGSSGDVKPALSPKEPKTLDTLPKPATTPTTEVCDDKFLFSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSK--SNDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSN----ISAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPP-PPPPP--SSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEK-HPKKEEKISSALSVLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGTVQGGYFPPVCGMESLFPYGPTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQK-------PVQAKTSKVESDQPQNSNDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFICRKCQMMFTDEDAAVNHQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQHLQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPNPNTTSTSQSAASSNNTYPHLSCFSMKSWPNILFQASARRAASPPSS-PPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQKLEDLDNSLEVKAKPASGLDGNFNSIRMDMFSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NXU9-1", "uniprot_id": "F6NXU9_DANRE", "id": "F6NXU9-1", "name": "Zinc finger homeobox protein 3", "aln": "METCDSPSLLRQENGQQISKLRETTHLDNEVPEKVPGMEPDKENSPADDNLRTEES--LREIASGLSAENAIG---TATKEIPCNECATSFSSLQKYMEHHCPNARLPLLKDENESEVSDLEDSDVENLTGEIVYQPDGSAFILEDSKEGGQNAQSGVKS-LFSPALFSNSQTAAGDKTEQSATAPMSFYPQVINTFHIASSLGKPFTADQAFPNTSALAGEGPVLHSFRVYDLRHKSDKDYLTIDGAAKNSCVSKDVPNNVDLSKFDGCISDGKRKPILMCFLCKLSFGYSRSFVTHAVHDHRMTLNEQEQKLLSNKYVSAIIQGIGKDKEPLISFLEPKKNNSMLPHFSTANFMGPDPGIRSLWN--TFHMENGDSLQAGFAFLKGSASLASSADQSPRSAQMPKAELNLGVMATSALKSPVSSVSLQRSSPGAG----YRDQESNCERQKDLSTLHANGELPIKSEPRDVADAEEEDMYSNELDDDGVC-ELEDSTSSKDFPLLNQSISPLSSSVLKFTERGTTSSV--TVANDFEKTKH----AAANLDYSNDSTSG--GSKDSCDSISGRGGSPPSLPLDLMRRDDESPGPLHQHAATPSTPGTPGPG-EGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLDAHMKEKHPESGGSCVYCRTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQTLQNGGTEAIYNHTTPVT----------------------------------NTSLTGCGTPSPS----------------KPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLG------------------LAPAEAELYQYYLAQNIGLTGMKLENPSDPQMMINPFQLDPSTAAALTPGHVNNELPAELRLASGQLMGDDLSVLSAGELSPCINDP----------LLKLFQCAVCNKFSSDSLEALSGHVATERS----LPEEEWRAVMGDVYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKANQWRLKCIA---IGNPVHLKCNACDYYSNSVEKLRLHATNQRHEAALKVYKHLQ-------KQESACNSESCYYYCALCDYSSRAKLNLLQHLRSVKHQQSEGLRKLQLHQQGLPPDEDNLADIFLVKDCPPNESEEP-----------------------GEDSEEFPQASSLAAAEDKDSSKRDAIEGKTTEKDSRINTLAKETLGIATAGKQSLQQEKENDTPPKRPKSAEEKTLSNEQVQQCPYCNYSNKDANRLQLHIMSQHSMQPVISCPLCQDVLSNKIHLQLHLTHLHSVAP--DCVEKLLMTVAGPDLPVPSSLLSASLQDKVPSLMDTSAVNPEGSGKTMGNSSKDLKNGTGQD--KSEVDLTSEELKPLKEAAEAPDWKKASGQDRKSPDALQEHLSDLQ----KRQQLSVSDRHVYKYRCNHCSLAFKTMQKLEIHSQYHAIRAATMCTLCQRSFRTFLALRKHLETGHPELTEAEVQQLCGNLPLNGDISESEMRALEEAQAFENELDKDEELDQEGKASPTGSDSSSLLDDMGSEPKRTLPFRKGPNFTMEKFLDP--SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVIQEASSPVPQETSNNVDNKPYKCNICNVAYSQSSTLEIHMRSVLHQTKARTAKLETSTSTGSGSSGSTSSKSPVPPNHGNTDSASAAPVSTNKENTVDAKEVTMKQTTEHIPVQP-NHPPTQSPAQLQMQLQHELQQQAAFFQPQFLNPAFFPHFPMTPEALLQFQQPQFLFPFYIPGAEFNISPELALHS-AAFGMPGMT----GSFLEDLKQQMQQQHQLGQQQQLQLSQQQAQQQASQSQMQQQKVQQ------------------QSHKPKTESNHNVLSEIQMSRDAEEHLEKQEGKAKQDTANENDNGKDAKDNRKPKFSEPLIPPPRIISGARGNAAKALLENFGFELVIQYNENRQKSQKKNK--EDELTDKLECGLCGKLFSNMLILKSHQEHIHGQFFPYVELEKFAQQYREAYDKLYPINPASPETPPPPPPPPPPPPPPAPLNTLPANASVGKSQTPSPAPIQTPQQAPQPPPPPPPPPP----TAPPQVQLPVSLDMPIFPPLMMQSVQHPGLPPQLALQLPTMDSLSSDLTQLCQQQLGLDPNFLRQSQFKRPRTRITDDQLKILRAHFDINNSPNEEQIQEMADKSGLPQKVIKHWFRNTLFKERQRSKDSPYNFNIPPMTTLEDIRLESQVNLLEYTRIDSASN--KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKTYENQADTKESEKKELTNERYIRTNNMQYQCKKCSVIFPRIFDLITHQKKQCYKDEDDEAGDEHILEDLSENIEQSLAKPMEAAKQS--------FVTASSSGSSSPLMPSPRPDIGKTSPKPELLNEKSKLG-ETAPLQTPKNP-----NELKPSKASTPQPLSQK--VPQPQLSRPHSQPQSTPVPSSPLSLALSSLNNSLPPQMLQYHCEQCKIAFPTVELWQEHQHMHFLAAQNQFLHSQFLERPLDMPYMIFDPNNPLMTGQLLSGALSQIPTASNSGLTMN----SNSLKRKLDEKEDG-SHEKDGLNSAEDQHRDKRLRTTITPEQLEILYDKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPSQTHKKCPFCRALFKAKSALDSHIRSRHWHEAKQAGFSLPPSPMMPQDDEGQSPHKYSFSDYLQMP-TKIEMN-ENEPPTASSTPV-KPSETLFKNFLNIPSLKAEHSDELEALNMSSAEASFDTNKMDFDETSSINTAVSDATTGDETNNEVEN---------LTINGSEKMIEN---KSNQAQTSDMNEDRFPFNMVSPALSFSGKDSDYFN--YRDDDFDDNADRSETSSLADPSSPSPFGSTNPFKSSKAGGERPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMISQGSPDGPRPECTLCGVKYTARLSIRDHIFSKQHIAKVQETLGNQVDREKDYLAPTTVRQLMAQQELDRLKKATDVLNLPAQQQPAVDNNALHGLSLPTAYPGISGLPPVLLPGVNGPSSLPGFPPNTPALASPGAGMLGFPTPATPSPAMSLSSTPTKTLLQTPPPPPPPQPSALPLPPTPLAANQTEQHIKESEKD--KKLEKPKVKEREADTARPETPIVKKKEKPSPPLSMLGKLGSEGQMDPAQLQALQNAIAGDPGSFLGGQFLPYFIPGFASCFSPQLPGGVQGGYFPPLCGMENLFPYGPAMPQAIAGLSPTALLQQYQQYQQSLQDSLQKQQHQQQQQQKQSEPQRKTPAPMKSTSAQSNSLK-PKETVETKDDKGSSTESTNEEPQTNTKSSGFPDAFIVPSIKHEFICRKCQMIFADEDSAARHQKSFCYFGHPFIDPQETVLRKAVSKYNCIACNVSVSGNEALGQHLQSSLHKEKTIKQAMRNAKEHARLLPHSVCSPNPNTTSTSQSAASSNNTLPHLSHLSMKSWPNILFQASARKAASCPSASPPPLSLPSTVTSTSCSTSGVQTSLPTESCSDESDSELSQKLDDLDNALEAKAKAASGLDGNFSSMRMDMFSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28167-1", "uniprot_id": "ZFH2_DROME", "id": "P28167-1", "name": "Zinc finger protein 2", "aln": "MSSFDVETFN----GKIVYNLDGSAHIIATDNTNGGGSGSGQNCYGSTTNSLKNLSKDKGRGQEEKDIEHPSQYHREQSDNKRQEEAVDNRPGVESLGSACYKSS--PKIHSFRVVSAQDANSTCQDQIRAFKIQKPILMCFICKLS--------------------FGNVKSFSLHANTEHRLNLEELDQQLLNREYSSAIIQRNMDEKPQISFLQPLANNDASADTNDTEKLQTATEGSDATLPSSPQ--------PVFRNVSELE-------------------------PENKQETEQNRLLNQDREQEPESDQHTSSSKMAAPSAYIPLSSPKVAGKLTVKFGSLNSATAKTNNLSKVSSTSSPPSTYASGEVLSPSTDNISNHKSTHCNQETEPPSSSSSEVEMKIGSMS--------TSPQTNDSDVPCSGFLQMQHMTTGGAYTPQVSSFHASLAALAANESNDNRVKLITEFLQQQLQQHQSS---LFPSPCPDHPDLNG-VDCKTCELLDIQQRSKSPSS-------------------SHHQFSQSLPQLQIQSQPQQTPHRSPCSNSVALPVSPSASSVASVGN-ASTATSSFTIGACSEHINGRP-QGVDCARCEMLLNSARLNSG--VQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHPRLARGESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNSSQNMVAAAAAAAVTGKLLLSSSSPQVTAACPSNSGSGAGSGSSNIVGGTASLSGNATPSVTGANSSNANAGSNTNNAGTKPKPSFRCDICSYDTSVARNLRIHMTSEKHTHNMAVLQNNIKHIQAFNFLQQQQQSGTGNIASHSSGSFMPEVALADLAYNQALMIQLLHQQQQHQQSANTKLSPSSSPVSTPDQFSFSPKPIKLNHGTGAAMGIGMAMGMGMSHSNEVSCELSGDPHPLTKTDKWPMAFYSCLVCDCYSTNNLDDLNQHLLLDRSRQSSSASSEIMVIHNNNYICRLCNYKTNLKANFQLHSKTDKHLQKLNFINHIREGGPQNEYKMQYQQQQLAANVVQLKCNCCDFHTNSIQKLSLHTQQMRHDTMRMIFQHLLYIVQQSEMHNKSSGSAEDDPQCACPDEDQQLQLQSSKKLLLCQLCNFTAQNIHEMVQHVKGIRHLQVEQFICLQRRSENQ--------------------------EIPALNEVFKVTEWVMENEDVSLAPGLNLARTTTNDAT-------TDASYAAASSAAVPAIPDVSMFSPTSPSSCATSCDKNLSQIVLPNVNN----------LGSGVPTTVFKCNLCEYFVQSKSEIAAHIETEHSCAESDEFITIPTNTAALQAFQTAVAAAALAAVHQRCAVINPPTQDTVDEDKDLDTNVSDGPVGIKQERLEQEVDRTTSMDVTKDLASQATDFGAPESPKVAETEVGVQCPLCLENHFREKQYLEDHLTSVHSVTRDGLSRLLLLVDQKALKKESTDIACPTDKAPYANTNALERAPTPIENTCNVSLIKSTSANPSQSVSLQGLSCQQCEASFKHEEQLLKHAQQNQHFSLQNGEYLCLAASHISRPCFMTFRTIPTMISHFQDLHMSLIISERHVYKYRCKQCSLAFKTQEKLTTHMLYHSMRDATKCSFCQRNFRSTQALQKHMEQAHAEDGTPSTRTNSPQTPMLSTEETHKHLLAESHAVEREVSGSDVSPIELETHLNKETRHLSPTPMSLDSQSHQKHLATFAALLKQQ---QCNSDAGGLHPEALSMSTGEMPPQLQGLQNLQHIQQHFGAVAAAAGLPINPVDMLNIMQFHHLMSLNFMNLAPPLVFGANAAGNAVSGPSALN-------NSITTSTATSASGLGDTHLTSGVSSIPVDSGKATAVPPQTQLN------------------------ANANSQQLASNQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYERTGQAKVTPLNDTCSVAVTGPMTSSTISLPPSGNIN-------LSSKENATSKVLAAGKANASGPVTFSATVPVSTPLSRPESTNSSGNISDYIGNNIFFGQLGSKEQILPYSLDGQIKSEP-------QDDMIGATDFAYQTKQHSSFSFLKQQQDLVDPPEQCLTNQNADTAQDQSLLAGSSLASN--CQSQQQINIFETKSESGSSDVLSRPPSPNSGAAGNVYGSMN---DLLNQQLENMGSNMGPPKKMQIVGKTFEKNVAPMVTSGSVSTQFESNSSNSSSSSSSTSGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNTLFENEETKKQ------NINYACKKCNLVFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAQNLSSEDSNSS-------------MDIHHVGICPPGSAVASHTLSTPGSAAPLPGQYTQHSFGALP-------------------------------SPQHLFAKSSSLTDFSPSTTPTPPQRERSNSLDQIQRPPKFDCDKCELNFNQLEKLREHQLLHLMNPGNICSDVGQNSNPEAN----FGPFGSILQSLQQAAAQQQQQHHQQ----------PPTKKRKYSDCSSNADEMQSLSELEASQKKHEYLYKYFMQNETSQEVKQQFLMQQQQKKLEQGNECDFELDFLTNFYQQNELKKVSNYDFLLQYYRTHEEAKSSQQHTFSSSKKPTIEFLLQYYQLNESKKFFQLVASPQIIPDVPGYKPS------------LRIPKSTSDEAPYIGETSLEQATELQ-----------REKQDEQLRIDRPSEENDLSMNKNKVENINNNNINVDQSNLTETNGG------------VPSVETKEECTQESSLIAMDDENKYLCTRSKQKDDKEKSHYLHNLEDFLDATMIENNSQTLTFNDDEKACQKDELTQNSNAIEKRSSVSPVNVSSKQNKRLRTTILPEQLNFLYECYQSESNPSRKMLEEISKKVNLKKRVVQVWFQNSRAKDKKSRNQRHYAHISDDNSYDGSSGKEVYSDLRSNG------------------ITVDTDLETNLQDCQLCQVTQVNIRKHAFSVEHISKMKKLLEQTTELYAQS-------------------------NGSGS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDNDSDREKRFYNLSKAFLLQHVVTN----------------------------------ATSHAIHTARQDSDVIAEGNCILNYDTNGGDSKSHVQHN------------LPNEVVSEDARKIAG--------------------------------------NQELMQQLFNRNHITVIGGK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: * .: *: :* ::: : * ..:: : * .: . . *:. :.: :*.. . ..::. . .: * ::. . .: :.: ::: . : :* .:* : * * : : . . : .: *::* : :: : : : . :. ..**. .. .: . .*: : . * .:.: * ::*::: . .: ..::*: ::.*:. *:: .*: . . ** * . * . :.::. : . . . .*: * .. :.. * .. : : .:.*:::* :: :* . . . .. :. .. : . :*.. .*. : : .::*::. . *.* ** :. :..:*.: ::..:.* : .. . .: . . . : * . . * . . :. * *: . :* * .*::*.:*: :*.*:* .* . * :**********:********:**: **:****: .:* ** :** **********: ****:***:***********************:* *:.. ::... .:**:* .*** : .* **: **::*.*:*.************** *** :**:*:*:** .* :. . * * * * : :: ..: :.* . :*. :: . *:* :.. : ::.* **: ::::.*: *. *: :** ...: .: .: * *:****:*:********.*****:** ::: **:*** *::::: .* *:****.**:::**::** **: : **:: :::** :: : .. . ** * : :*: ::: : : . . :: *: . :: ::: :: . *: : . . ::. : . .: : :*. .... : . ...:. . . ::. * * .. :.. .*: * **: .:..* .: *: ** : : : *.. . : : : ..: . ...* . . * : : *: ... . . . :..:: .. . .:. : : ::* *. *:. : * : ::: ::.: * ..* .: * :: : .* :: : .:.::* . :. . : :. ::: ... :. : . : . . : : :: *. ::. *:*. *. :*. :: * .* * . * : : . .* .. :: : . .. ....* : ... :: *.: :* . . . : . : . * . . *. * :. : : . ** * : :* * : *: .:* :* * . :*:.* :*:: * :.*:.: : . : :. * ..:. . .. :*: : . .. . : . ..:: : : . :. :: : : .: . :. : : : : . : : . :.*: . . * :: ::..: .:. . . * : *. : * . : :: * . * .* . * .. . : . : .: : ...: : *: : * : * : *. ..*. : :.*:: .*: ... .:* . *... : .* .* :: ::: * :: : ...:: . .*:.. .: : : . : .:: . **:.********::***:**:.*:****.::* **.:* *..************* ** ****.: . *:.* .:: *::* ****.::* * ::** ***::*:*:*::. : : . * ..* . . . .. . : .: . : * * : . .. :* .:.. * . . : :: *::* : * :* :*** :*:: . * . ..* *.* ..:: . ..: * . . : *** .: ... :. : .*::.: * . : :: . .: :* .: :*: : :. *. . :: : .. . : :: . :.. ::: .:*.. ..: . : : .: :.* .** : : * .* :* . .:* . .*.: :.:* * :: :: .. : . . .* ..:: .. * :.::. : ::. .* : . .. : . . : : . :. :. . : .*.:. * : .. . : . . . . :**:** : **:.* *:.. .*: : * :.:::.* **********:***::* : : ..: .:.. :*. : . ..:: .. *:..::: : : * *: ::. ::: :.: * * . **..* ** ::* * :.:.:: : .. : .:*::.*::. ::... * :*.. . .: .:* ** :.. .**: *. :.** *:* : :: .* ", "identical_positions": 473, "similar_positions": 1032, "identity": "12.62%" }, { "cls_id": "homologset.agr.MGI:2137670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62764-1", "uniprot_id": "YBOX3_RAT", "id": "Q62764-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTGG-TTLPQAAADAPAAAPPDPAPKSPAASGAPQ--APAPAALLAGSPGGDAAPGPAPASSAP-----AGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGAQLQ--VHRNPTYRPRFR-RGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRPRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKB3-1", "uniprot_id": "YBOX3_MOUSE", "id": "Q9JKB3-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTGG-TTLPQAAADAPAAAPPDPAPKSPAASGAPQ--APAPAALLAGSPGGDAAPGPAPASSAP-----AGGEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGTQLQ--AHRNPTYRPRFR-RGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRSRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16989-1", "uniprot_id": "YBOX3_HUMAN", "id": "P16989-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTTTTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPNRIQAGEIGEMKDGVPEGAQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENPAPPTQQSSAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********* ******.::*.**** *******..***** ****** :**.*******..: :::*. **.********************************************************************************************************************************:***:* **************** *********************:*****:***************:*** .*********:* ***.*******:***********:.******.***:*********.** ** ******:************.*:*****", "identical_positions": 319, "similar_positions": 33, "identity": "85.75%" }, { "cls_id": "homologset.agr.MGI:2137677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63965-1", "uniprot_id": "SFXN1_RAT", "id": "Q63965-1", "name": "Sideroflexin-1", "aln": "MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPKNILLTNEQLENARKVVHDYRQG-IVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALT---KHVSP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDDLQASIQKSHPELRRVYFNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JR1-1", "uniprot_id": "SFXN1_MOUSE", "id": "Q99JR1-1", "name": "Sideroflexin-1", "aln": "MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPRNILLTNEQLENARKVVHDYRQG-IVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALT---KRVSP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDELQASIQRTHPEIRRVYFNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9B4-1", "uniprot_id": "SFXN1_HUMAN", "id": "Q9H9B4-1", "name": "Sideroflexin-1", "aln": "MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQG-IVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALT---KHVSP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5W5-1", "uniprot_id": "F1R5W5_DANRE", "id": "F1R5W5-1", "name": "Sidoreflexin", "aln": "MAATISTSINIKEPRWDQGTFVGRAKHFFTVTDPRNILLSNKQLEKAHQIIQDYKKG-VVAADLTEDELWRAKYVFDSAFHPDTGEKMLLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAIVNYTNRSGDAPITVNQLGTAYVSATTGAVATALGLNALA---KHVSP----LIGRFVPFAAVAAANCINIPLMRQRELKHGIPVTDENDNRLGESSKAAQQAITQVVVSRILMASPGMAIPPFLMNSLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMAVSRLEPELQEKIRASHPGVETVYFNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN13-1", "uniprot_id": "SFXN1_DROME", "id": "Q9VN13-1", "name": "Sideroflexin-1-3", "aln": "MS--PLPRVNIDEPKYDQNSYLGRAKHFFLLTNPLNVLASASKLEEARQIVIKYRAGKDVPECKTIDDVWRAKYLYDSAFHPETGEKQIVIGRMAAQMPMNTIITGGMMAFYKSTPAVVFWQWFNQTFNAIVNYTNRSGTSPISQQQLVTSYCLATSGALVTALSLNHAV---KNMNP----LLGRLVPLVAVGAANCINIPCMRMQELRNGVTLFDEHSNEMGISKKAAVVGISTVILSRIAMAIPGMTLTPVLMNVLEKRGFLAKYPRSNAPIQTLFCGFVLIFATPLGCAFFKQRADIKVDSLESEVRDSIRKKRPELETVWFNKGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHG---ELKETTPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMSTSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKLEPELHGKKDKDGKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::: *.::* .:: ** * :::* :* : ..* *:::: *: * * :.**** **:.**:**:. : **:::: * :* *:: *...:**** **::*. ** :* . *:: .:* * * *.:.: .**.** . *.:.* ::**:**:.** :*. :*: ** .*:: *:.: *.:. .:* * :** .: . :**: * * *.:.*.:: *:: : : .: : : .. :. * *: .:* *: : : ** ::: . :. *:**:*:", "identical_positions": 84, "similar_positions": 119, "identity": "25.45%" }, { "cls_id": "homologset.agr.MGI:2137678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925N2-1", "uniprot_id": "SFXN2_MOUSE", "id": "Q925N2-1", "name": "Sideroflexin-2", "aln": "---------------MEGDLSGFNIDAPRWDQCTFLGRVKHFFNITDPRTVFASEQELDWAKAVVEKSRMGLVPPGTQMEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQVPGGMLITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVG-------MNMWTKRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQGICVKDRNQNELGHSQRAAAVGIAQVVISRITMAAPGMILLPVIMERLERLHLMKKVKVMHAPLQVLLCGCFLLFMVPVACGLFPQECELSVSYL---EPELRDTIKAK-YGEQVLFVYFNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G419-1", "uniprot_id": "A0A8I6G419_RAT", "id": "A0A8I6G419-1", "name": "Sidoreflexin", "aln": "---------------MEVDLSGFNIDAPRWDQCTFLGRVKHFFNITDPRTVFVSEQELDWAKSVVEKSRMGLMPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQVPGGMIITGFMLQFYRTMPAVVFWQWVNQSFNALVNYTNRNAVSPTSVRQMALSYFIATSTAVATAVG-------MNLWTKRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQGICVKDRNQNELGHSRRAAAVGITQVVISRITMAAPGMILLPVVMERLERLHLMKKLKVLHAPLQVLLCGCFLLFMVPVACGLFPQECELPVSYL---EPELQNTIKAK-YGEQVLFAYFNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NB2-1", "uniprot_id": "SFXN2_HUMAN", "id": "Q96NB2-1", "name": "Sideroflexin-2", "aln": "---------------MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVG-------MNMLTKKAPPLVGRWVPFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYL---EPKLQDTIKAK-YGELEPYVYFNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GUY0-1", "uniprot_id": "A0AC58GUY0_DANRE", "id": "A0AC58GUY0-1", "name": "Sidoreflexin", "aln": "MHEVSCGLRMISRERTMEAVKGFDIDAPRWDQSTFMGRLKHFFNITDCRTALLPDSRLDEAKVLVESCRAGSVPPGTTEEQLHYAKKLYDSAFHPDTGDRMNLIGRMSFQVPGGMAITGFMLQFYRTVPAVVFWQWVNQSFNALVNYTNRNAASPITPKQIGVAYVTATSTALATAVG-------LNLYTKKAPPLVARWVPFAAVAAANCVNIPMMRQQEILHGIAVTDEDGNKLGHSRKAAVKGITQVVISRVTMAAPGMIILPIIMQRLEKHRFMQKITFLHGPLQVMMVGVFLIFMVPAACSLFPQRCSMAVSKL---EPELRESIISQ-YGEQISHVYFNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVW3-1", "uniprot_id": "SFXN2_DROME", "id": "Q9VVW3-1", "name": "Sideroflexin-2", "aln": "---------------MSQVSTLIDVDKPLFDLSTFAGRFQYFAWMTDPRTVVVSSDRLLEAKAMVERYRKGDQSPPLKPEEVHYNMKLYNSAFHPDTGELQNFCGRMSFQVPGGMLITGGMLAFYRTVPAVVLWQFINQSFNAVVNYTNRNANSPTSVTQLGVAYVSATTSALVAAIGC------KNYWSKKATPLFQRFVPFAAVAAANFVNIPLMRQNEIINGIEVKNDDGVVVGQSRLAAIKGIGEVVVSRIAMAAPGMLVLPLIMERLEKLPAYRRIKWINAPFQTLLVGCFLCFMVPTACALFPQQCSLDTSIMRTFEPELYEDLEKKTQGKVPKRVYFNKGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "--------------MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHGELKETTP--EFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMSTSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKL---EPELHGKKDKD--GKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . :* *: **.:: ::* . .. * *: ::. * * :. * :*:.*****. . *** :: ..: :* ** ...::**: ***:*. ** :* * * : *: * *.::: .*:* : : :: :. * ******.:*. **: :** :*: :** * : : :*:*: ** .: :..:**: ::* *:: *::: **:: : :: : : . : :* * .:***. : . : **:* . *: .***:*:", "identical_positions": 78, "similar_positions": 103, "identity": "22.41%" }, { "cls_id": "homologset.agr.MGI:2137679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91V61-1", "uniprot_id": "SFXN3_MOUSE", "id": "Q91V61-1", "name": "Sideroflexin-3", "aln": "-MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGEQLEASRNIVQNYRAGVATPG-LTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLT---KHLPP----LVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVISRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQNPSIDVVYYNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHY2-1", "uniprot_id": "SFXN3_RAT", "id": "Q9JHY2-1", "name": "Sideroflexin-3", "aln": "-MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGKQLEASRNIVQNYRAGVVTPG-LTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTMVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLT---KHLPP----LVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVVSRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQKPSIDVVYYNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BWM7-1", "uniprot_id": "SFXN3_HUMAN", "id": "Q9BWM7-1", "name": "Sideroflexin-3", "aln": "-MGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAGVVTPG-ITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDTPITVRQLGTAYVSATTGAVATALGLKSLT---KHLPP----LVGRFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMAIPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISNLEPELRAQIHEQNPSVEVVYYNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN13-1", "uniprot_id": "SFXN1_DROME", "id": "Q9VN13-1", "name": "Sideroflexin-1-3", "aln": "-MSPLPR-VNIDEPKYDQNSYLGRAKHFFLLTNPLNVLASASKLEEARQIVIKYRAGKDVPECKTIDDVWRAKYLYDSAFHPETGEKQIVIGRMAAQMPMNTIITGGMMAFYKSTPAVVFWQWFNQTFNAIVNYTNRSGTSPISQQQLVTSYCLATSGALVTALSLNHAV---KNMNP----LLGRLVPLVAVGAANCINIPCMRMQELRNGVTLFDEHSNEMGISKKAAVVGISTVILSRIAMAIPGMTLTPVLMNVLEKRGFLAKYPRSNAPIQTLFCGFVLIFATPLGCAFFKQRADIKVDSLESEVRDSIRKKRPELETVWFNKGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHGELKET---TPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMSTSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKLEPELHGKKDKDGKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* ::: *.::* .:: ** :* :::* :* : .* :*:*: ** * :.**** **:.**:**:. :: **:::: * :* *:: *. ***** **::*. ** :* . *:: ** * * *.:.: .**.*: . *:: * ::**:**:.** :*. :*: ** .*:: *:.: *. .:.:* * .** .: . :**: * * *.:.*::: *:: : : : : : .. :. * *: .:* *: *:: **.*:: . . :: *::*:*:", "identical_positions": 87, "similar_positions": 115, "identity": "26.36%" }, { "cls_id": "homologset.agr.MGI:2137680", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925N1-1", "uniprot_id": "SFXN4_MOUSE", "id": "Q925N1-1", "name": "Sideroflexin-4", "aln": "------------------------MEPNLQFWISERQAFFRRFCQWMDLLDPVNMFISIGSIEKSRQLLFTTEDAPKHYLDNQVIKDAWNKSLSTVHPDSSKLIPHLFRPAAFLPVTAPMVFLLMMPDTGIKSIILTQGCLYGYTTAFNITNGNASYSHG---PVERTLLGAGVSVSSTFIGLIPHLFQMKY----PPNNFWLKRTLPIVFLAQVSGMNVFASRSFENHRGIEVMDKEGHVVGHSRKAGRKAIKDTAKSRAVLFGTSALAPELFIHIFKRTRFYPQTLLSLVILRMSSTFFMMGLMVPVSFSMFPQIGQIQCSQLEEKIQSSTEE-----KELFYYRGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G785-1", "uniprot_id": "A0A8I6G785_RAT", "id": "A0A8I6G785-1", "name": "", "aln": "------------------------------------MSFFRRFCQWMDLLDPVNVFISVESIEKSRQLLFTTEDAPKHYLDNQRVKDAWNKSLSTVHPDSSKLIPHLFRPAAFLPVTAPMVLLMMMPDTGIKSIILTQGCLYGYTTAFNITNGNASYSHG---PVERTLLGAGVFASSTFFGSIPHLFQLKY----PLNNLWLKRFLPIIFLAQISGMNVFASRSFENHRGIEVMDKEGHVIGYSRKAGRKAIKETAKSRAVLFGTSALAPELFIHIFKRTRFYPQTLLASVILRMSSTLFMMGLMVPVSFSMFPQIGQIQCSQLEEMIRSSTEE-----KELFYYRGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4A7-1", "uniprot_id": "SFXN4_HUMAN", "id": "Q6P4A7-1", "name": "Sideroflexin-4", "aln": "MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCK---PLERSLLMAGAVASSTFLGVIPQFVQMKY----GLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEE-----TEIFYHRGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E7G5-1", "uniprot_id": "SFXN4_DANRE", "id": "A8E7G5-1", "name": "Sideroflexin-4", "aln": "------------------------MDPNLQYWQNNGQSFLSRLGLWSKILDPT-LLLSQAEIEEARTLIQNEENTPG---KNDKVSNAWLLSLSSVHSDTGAVISPAYRPQVFLPISAPLVVGSLIAHKGIKSAMFWQFVLHTYCAGFNHANRNATATKDNKTTMKQSLLILGAVSYSTVTGALPQIILQRLRLISSLTQTICRSFLPVPLAAGLAAFNILVVRSEEAENGISLFDANGNAVGVSKEAGFKAVKETAISRATLFGTTAALPTFLMALLERAKFVQRNPRLIAPIGSMCTVITFGLMIPVSFSLFPQLGKIKKENLEKEFQSLDGN-----EELFYHRGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "------------------MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYR-HGELKETTPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMS---TSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKLEPELHGKKDKDGKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: .: **. :: : .: .:* :: . . * ::**.*:. : :* : .. : . * . :: * ...* * * : . . : .. * . : . : . :*. . . .*: *. * .** ::* :*. :* *: *. *: :* ** .: * .: ::* :. . : :*.::.:*** *: .** ::. : :::: **:", "identical_positions": 41, "similar_positions": 90, "identity": "11.75%" }, { "cls_id": "homologset.agr.MGI:2137681", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925N0-1", "uniprot_id": "SFXN5_MOUSE", "id": "Q925N0-1", "name": "Sideroflexin-5", "aln": "MADTATTASAASAAASAPNASTDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARP-RLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIARATS-----SRTVVYNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CFD0-1", "uniprot_id": "SFXN5_RAT", "id": "Q8CFD0-1", "name": "Sideroflexin-5", "aln": "MADTATTASAASAAASASNASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARP-RLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIARATS-----SRTVVYNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TD22-1", "uniprot_id": "SFXN5_HUMAN", "id": "Q8TD22-1", "name": "Sideroflexin-5", "aln": "MADTATTASAA--AASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARP-RLLLPVQSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIAQATS-----SRTVVYNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R7K0-1", "uniprot_id": "F1R7K0_DANRE", "id": "F1R7K0-1", "name": "Sidoreflexin", "aln": "MAESAS-----------------CPRFLLGKPRFEQSTFLGRLRHFIDIIDPSTLFVTESRLKECMKLLDDFKRGNLPAGVTDQQLWEAQKVKQAIIHPDTGEKIFMPFRMSGYVPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPTPTSKFIQGYVGAVTSAVSIAVGLNVLIQKSSKFNPATRLFIQRFIPFPAVASANICNVALMRHNELSEGIDVLDSDGNVVGSSRIAAKHALIETALTRVALPLPIFVLPPIIMAFLEKLPLLQARR-RLMLPVHSLVCLLVFGLSLPLAISLFPQMSEIEASHLEPEIAMATD-----CKVLTYNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P320-1", "uniprot_id": "A0A8M1P320_DANRE", "id": "A0A8M1P320-1", "name": "Sidoreflexin", "aln": "MPESTE-----------------FPPFRLGESRFDQGSFYGRLRHFLDVIDPRTLFVSGRRLNECMKLLDQFKNGTLPPGVTNGQLWKAQKIKQAIIHPDTGEKIPMPFRMSGFVPFGTPVVVGLLLPNQTFSSTIFWQWLNQSHNACVNYCNRNATKPTPISTFFQGYLGAVSSAVTIAVGLNVLIKRAEHFSPATRILVQRFIPFPAVASANVCNVLLMRHTELSEGISVLDDKGNVVGTSKLAARHALIETSLTRVVLPMPVLLLPPLVMSLLERLPFLQKRP-RVTLPDHSMVCLCAFGLALPVAISLFPQNSQIHVSELEPKISAATH-----CQILTYNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "MASSVP------------------GPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHGELK--ETTPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMSTSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFS-ALPFALGIFPQRQAIHLNKLEPELHGKKDKDGKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..:. : * :.*:: :: **:** :: ** *:.: * .. :::. ::.* * * ::* *:* :: :****.:.: :*****. : . :.**:* *. :.*:**** *** *..** .* * ::* . * :: .* .** :: :*:*** *: : .::.* ::::: *::**.**.**.: ** *** *: :**.*:* .*: **.*: ** *: **:*:** . * :::**::: *:: : *. .::.: *. :**.*:.:*** . *. ..***:: . . : :*:*:", "identical_positions": 101, "similar_positions": 123, "identity": "29.02%" }, { "cls_id": "homologset.agr.MGI:2137698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V9X9-1", "uniprot_id": "Q9V9X9_DROME", "id": "Q9V9X9-1", "name": "UDP-glucuronosyltransferase", "aln": "----MPPIFLLVCLLP--GYSEG-ARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQ-----REPFRNIHDIPVPEVFENFN-EVLRIASTPRSTWQSSDFINEYVLN--LTKT-VLNNEGVRRDILG------PQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVR--KQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFT-LGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDEL-LPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKKIQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT5-1", "uniprot_id": "Q9VGT5_DROME", "id": "Q9VGT5-1", "name": "UDP-glucuronosyltransferase", "aln": "----MRTFTLILGLLCSLGYSSG-YNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQ-----KKPIPGYTDVSVPNVIEVMGGDIGALWASIQKTYTQN-LIDHYQMG--FRITRGLFEDSNFQDFLK------SNQ-SFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLP--TQEKLYKEFFP--GNKRCFYKMRRNASLVLINQHVS-LSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFIN-ESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDN-LPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTKVKRN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG30-1", "uniprot_id": "Q9VG30_DROME", "id": "Q9VG30-1", "name": "", "aln": "MVHKSGIYLLLATAICVLGGCHG-ANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKP--VVNHKNITVIMVPLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDLYL------NRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEKG-KGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLG-NATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIF-------AKPKKEKKH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJH9-1", "uniprot_id": "Q9VJH9_DROME", "id": "Q9VJH9-1", "name": "", "aln": "MIEYTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPK-LATHENITVIIAPPTEERQRYIKEYMAEVSN-EKPSFWETMVKAIVQSSNQLEGQYEFMTHPNVKEIYE------NPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLD-KADEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQRKAVANKLKNN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64435-1", "uniprot_id": "UD16_MOUSE", "id": "Q64435-1", "name": "UDP-glucuronosyltransferase 1A6", "aln": "MACLLPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNL-LLGESKYYRRKIFSVTYSLEELQTRFRTFGNNHFLPG-ASLMGPLREYRNNMIVVD-MFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVI-LAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSK-------YEIIASDLLKRDVSLPSLHQN-SLWLLRYDFVFEYPRPVMPNMIFLGGINCK-KKGKLTQEFEAYVNASGEHGIVVFSLGSMVS--EIPEKKAMEIAEALGRIPQTVLWRYTGTR-PSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08430-1", "uniprot_id": "UD16_RAT", "id": "P08430-1", "name": "UDP-glucuronosyltransferase 1A6", "aln": "MACLLPAAR-LPAGFLFLVLWGSVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNL-LLGESKYYRRKSFPVPYNLEELRTRYRSFGNNHFAAS-SPLMAPLREYRNNMIVID-MCFFSCQSLLKDSATLSFLRENQFDALFTDPAMPCGVI-LAEYLKLPSIYLFRGFPCSLEH-IGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILENYLYHCLYSK-------YEILASDLLKRDVSLPALHQN-SLWLLRYDFVFEYPRPVMPNMIFIGGTNCK-KKGNLSQEFEAYVNASGEHGIVVFSLGSMVS--EIPEKKAMEIAEALGRIPQTLLWRYTGTR-PSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19224-1", "uniprot_id": "UD16_HUMAN", "id": "P19224-1", "name": "UDP-glucuronosyltransferase 1A6", "aln": "MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNL-LLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAER-SFLTAPQTEYRNNMIVIG-LYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVI-LAEYLGLPSVYLFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSK-------YEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCK-KRKDLSQEFEAYINASGEHGIVVFSLGSMVS--EIPEKKAMAIADALGKIPQTVLWRYTGTR-PSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NVN7-1", "uniprot_id": "A0A8M1NVN7_DANRE", "id": "A0A8M1NVN7-1", "name": "UDP-glucuronosyltransferase", "aln": "MASVL---------LFCLFCLASAKAGKILVVPSDGSHWMGIKPLVEELGRRGNQVVVVIPEASL-SMGPSQHTTTLTYPVPYTKAQIQDHISASVTNLISTHVSTDLARFQSFINTMDLLSNLITRNVEGLLLNKDLMKKLQDYNFDVILTDPFETVGVI-AAEYLSIPTIYIQTSHPCGADTLASQCPSPPSYVPQRLTHFSDRMNLWQRSVNFVRTLIQPMACRRMFTR-------ADEIASRVLQRKTSIMDIMGRAALWFVHSDFALEFPHPLMPNMIIVGGMDNR-KAEPLSQELEEFVNGSGEHGFVVFTLGSMVS--QLPEAKAREFFEAFRQIPQRVLWRYTGPV-PENAPKNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2J3-1", "uniprot_id": "Q9W2J3_DROME", "id": "Q9W2J3-1", "name": "UDP-glucuronosyltransferase", "aln": "MQFPLLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAE-----QKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFP--KMDAVAREFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIY-PPKPLPADMQALLD-GATEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDES-ISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIRLLMGSNKKHRKAKQN--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . ** . * *: : : . . . : . ** :: * * : ::: . . . : :* : :** . *. .: : . * : :::*: :. : : ..: : * ::*:: . * .*:** :*.* *:.*.* . *. . *:: :* ** * * . . : : :: : : : . : .:*: . . .::* *.* *:** ::: . : :*: . : ", "identical_positions": 40, "similar_positions": 92, "identity": "7.3%" }, { "cls_id": "homologset.agr.MGI:2137706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1P2-1", "uniprot_id": "ACTN1_RAT", "id": "Q9Z1P2-1", "name": "Alpha-actinin-1", "aln": "--MDHYDSQQ----------TNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMQAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHSRQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQ----------------------GEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITGDELRRELPPDQAEYCIARMAPYAGPDSVPGALDYMSFSTALYGESDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPR4-1", "uniprot_id": "ACTN1_MOUSE", "id": "Q7TPR4-1", "name": "Alpha-actinin-1", "aln": "--MDHYDSQQ----------TNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLECDHQLIQEALIFDNKHTNYNMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQ----------------------GEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITEDELRRELPPDQAEYCIARMAPYAGPDSVPGALDYMSFSTALYGESDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12814-1", "uniprot_id": "ACTN1_HUMAN", "id": "P12814-1", "name": "Alpha-actinin-1", "aln": "--MDHYDSQQ----------TNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQ----------------------GEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T375-1", "uniprot_id": "A0AB32T375_DANRE", "id": "A0AB32T375-1", "name": "", "aln": "--MDHHHHPQHHHHHQYDGGENDYMQQEDDWDRDMLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALGFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYNKLRKDDPMTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMQAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDISNSWGRLEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKAAIHEAWTDGKEEMLQHKDFETASLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELEYYDSPSVNARCQRICDQWDSLGVLTQKRSEALQRTEKLLETIDQLYLEFAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLSTAHEQFKATLPEADKERQAILGIHNEIAKIVQTYHVNMAGQNPYTTINPQEINAKWDKVRQLVPQRDQALIEEHARQQNNERLRRQFANQANVIGPWIQTKMEEIGRISIEMHGTLEDQLTHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEIENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGAEEFKACLISLGFDIGNDAQKRTGMMDAEDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKVLAGDKNYILADELRRELPPDQAEYCIARMTPYSGPDSVPGALDYMSFSTALYGESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18091-3", "uniprot_id": "ACTN_DROME", "id": "P18091-3", "name": "Alpha-actinin, sarcomeric", "aln": "MMMENGLSMEYG---------DGYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNVTHVPEPTRQYTYVPNNYNAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGISQEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQ----------------------GDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGALDYMSFSTALYGETDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : :.**: *::*:*: **********:**************** *:*******:************** *.**:*****.***:******.*******:************* *********************** :********************:****:*:****.**********:**** ** **:*: **********::****:***.:*::.*.:***:*******.:****.***:. *********** ******:***:**:************:***:.* .:*:: .:*:***::* *** ****:*::*.:** ****************::*:**: ****.*:* ** .**.:***** * *****:***:**::** ** ** *** **: :*:. ..*.*:*** **************************** *:*:*. *******:****** **.***:* **:.:*::**.** *:**:**********::*: *** * *****:****** **:****** :**** *:.: .*: .**: ::: . *****:..:::. **..******:***:* :* :**:** **:**. :**::****: :*: : *.: ::*:***** :*::**::: ***:*::** ** :**::**:*::***.** :*********:* *.***:********:*******:****:******::::* *..****:**:***:.**:* * *: :* **:::****. * * *:**:***:**::*****:**: **::**.** ** **************** **.** **:.*****************:**", "identical_positions": 606, "similar_positions": 197, "identity": "63.92%" }, { "cls_id": "homologset.agr.MGI:2137858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1WIM3-1", "uniprot_id": "CADM3_RAT", "id": "Q1WIM3-1", "name": "Cell adhesion molecule 3", "aln": "---------MGAPSA--LPLLLLLACSWAPGG---ANLSQDDS--QPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLAWRKGDQELHGDQT----RIQEDPNGKTFTVSSSVSFQVTRDDDGANVVCSVNHESLKG--ADRSTSQRIEVLYTPTAMIRPEPAHPREGQKLLLHCEGRGNPVPQQYVWV-KEGSEPPLKMTQESALIFP--FLNKSDSGTYGCTATSNMGSYTAYFTLNVND-----------------------------------------------------------------------------------------------------PSPVP----------------------SSSSTYHAIIGGIVAFIVFLLLILLIFLG----HYLIRHKGTYLTHEAK---GSDDAPDADTAIINAEGGQSGGDDKKEYFI-------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N28-1", "uniprot_id": "CADM3_MOUSE", "id": "Q99N28-1", "name": "Cell adhesion molecule 3", "aln": "---------MGAPSA--LPLLLLLACSWAPGG---ANLSQDDS--QPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLTWRKGDQELHGDQT----RIQEDPNGKTFTVSSSVSFQVTREDDGANIVCSVNHESLKG--ADRSTSQRIEVLYTPTAMIRPEPAHPREGQKLLLHCEGRGNPVPQQYVWV-KEGSEPPLKMTQESALIFP--FLNKSDSGTYGCTATSNMGSYTAYFTLNVND-----------------------------------------------------------------------------------------------------PSPVP----------------------SSSSTYHAIIGGIVAFIVFLLLILLIFLG----HYLIRHKGTYLTHEAK---GSDDAPDADTAIINAEGGQSGGDDKKEYFI-------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N126-1", "uniprot_id": "CADM3_HUMAN", "id": "Q8N126-1", "name": "Cell adhesion molecule 3", "aln": "---------MGAPAASLLLLLLLFACCWAPGG---ANLSQDDS--QPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPT----RIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG--ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWE-KEGSVPPLKMTQESALIFP--FLNKSDSGTYGCTATSNMGSYKAYYTLNVND-----------------------------------------------------------------------------------------------------PSPVP----------------------SSSSTYHAIIGGIVAFIVFLLLIMLIFLG----HYLIRHKGTYLTHEAK---GSDDAPDADTAIINAEGGQSGGDDKKEYFI-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H5F7-1", "uniprot_id": "A0AC58H5F7_DANRE", "id": "A0AC58H5F7-1", "name": "", "aln": "MSGMRARQTLAFPSFQRAALRALAAFTMILATSVRSNYVYDDDPFQPVTQDETVAVGGVVTLTCGVKENDNSSLQWSNTAQQTLYFGEKRALRDNRIQLVKSTATELIITIGDVQLSDDGEYTCSIFTMPVRTARATVTVLGVPGKPVITGFEGAVQEGGKVTLTCTSSGSKPPAKLHWYRDHVEIQGRPD----VVESNPNEPTYTVTSELTLSVSRDDNDALIACAVDHPSIAN--GDKRTEQPLNVLFSPRVSIHPESDLPREGEKFYLQCVGNGNPEPNAFVWRRKEGELPPLAKVDGAFLRFE--SLNKSDNGVYECQADNGIGMGDVAHTLLVQEGDPDYLIPSFTLPSSTVSPTSLSQTSVLPSTEGETLPPTSSSSSSTVIPTFTLPIPSTPSAPPTVPPSPESPTTALSNALFPELTPPAYTPPSTPTIPPATPSSVPRLNGVYTFTEAGENAADPTAMSTGSGVDHAVIGGVVAVIVFIMLCLLLVLG----RYLIRHKGTYLTHEAK---GSDDAPDADTAIINAEGGHSGVDDKKEYFI-------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15278-1", "uniprot_id": "FAS3_DROME", "id": "P15278-1", "name": "Fasciclin-3", "aln": "---------MSRIVFICLAAILTDALTWAQVNVEPNTALLNEGDRTELLCRYGRSINYCRIEIPGEQKVLNLSPEWS-KTPGFTYFGAGLTAGQCGVSIERVKASNNGQVKCSLGVEGEELSGTIDLVVALRPQQPIIELLSRPNR------EGYFNEGTEFRARCSVRDGRPPANISWYIDNMPANKRTTPLEVMSSTNDNVELSTSVQEIQWHLSPEDSNRKLVCRSHHQTDRESVPPQEAAYIINVRYAPVHQPDAAVYGLYLEHTAIVNITIRASPQP-KIEWT-IDGAIVGQGRTDGRYSAYEPQYLGNDEYNVTLAIAGLTLEDTTKIYNLRASN-----------------------------------------------------------------------------------------ELGLTDYQVRISSSSKP---------------------PSSSLDVAAIVGIVVAVAVLVLVVLLIVFARATGRWCFGGKSIKTPTNETSDTESADIKATSTATATTTMGGVGVSAEEEETVNEQESPQEQQQQQQKKAKRLPAFAAAILRRFNEKDSRKYKDNQESLNIVEGSVQEIPATNNAIDGNDNEPKAIVWQSTSPVWTFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * . ::. . :. : * :** : *** : : :.: .. : .: : .: :.:.:*. :. : :*. * : :. ..* * ..:*.*.: * .. : . : * * ..: :: :*.. :.* .* : : : ::* ::* . .. :: ...* * * :* .: : *.:.: .. . * : ..* ..: .*. * :.* *::* :**. *:::: :*:.:. :: : *. . : . * * :.** .: * * . ::* : ", "identical_positions": 46, "similar_positions": 127, "identity": "7.23%" }, { "cls_id": "homologset.agr.MGI:2137870", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHS0-1", "uniprot_id": "D3ZHS0_RAT", "id": "D3ZHS0-1", "name": "", "aln": "MEASGSSSQSPNSSAVHRETEDLNHPETEFHKQHGKA----RERYERDKSSSSSSSSSSSSSSSSSSSSSSSS-----------------------------GADHGELEVLKDELQLYGGAAGEMVLAGESGLRRRGSGSAEGEVEASQLNRLNIKKDDEFFHFVLLCFAIGALLVCYHYYSDWFMSLGVGLLTFASLETIGIYFGLVYRIHSVLQGFIPLLQKFRLPGFRRTN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4FJU9-1", "uniprot_id": "TMM40_MOUSE", "id": "Q4FJU9-1", "name": "Transmembrane protein 40", "aln": "MEASGSSSQSQDSGGVHRETEDH-YQETELHKHHGKA----RERYKRDKSSSSSSSSSSSSSSSSSSSSSSSDSSDEDQPSRGPRKHRR-----RPRRDSLRGADHGELEVLKDELQLCGGAAGEMVPTGESGLRRRGSGSAEGEVEASQLRRLNIKKDDEFFHFVLLCFAIGALLVCYHYYADWFMSLGVGLLTFASLETIGIYFGLVYRIHSVLQGFIPLLQKFRLPGFRRTN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWA1-1", "uniprot_id": "TMM40_HUMAN", "id": "Q8WWA1-1", "name": "Transmembrane protein 40", "aln": "METSASSSQPQDNSQVHRETEDVDYGETDFHKQDGKAGLFSQEQYERNKSSSSSSSSSSSSSSSSSSSSSESN--DEDQQPRATGKHRRSLGAGYPHGNGSPGPGHGEPDVLKDELQLYGDAPGEVVPSGESGLRRRGSDPASGEVEASQLRRLNIKKDDEFFHFVLLCFAIGALLVCYHYYADWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLQGFIPLFQKFRLTGFRKTD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.****. :.. ******* : **::**:.*** :*:*:*:**********************.*. *..*** :******** *.*.**:* :**********..*.********.******************************:******************:********************:*****.***:*:", "identical_positions": 160, "similar_positions": 34, "identity": "68.09%" }, { "cls_id": "homologset.agr.MGI:2137896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7N7-1", "uniprot_id": "G3V7N7_RAT", "id": "G3V7N7-1", "name": "E3 SUMO-protein ligase ZNF451", "aln": "----------------------------------MLLFFFFFFFFWFFFSELGTEPRPCASQENFKHKDYIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIQGHSETEAARQCVDQWLKMSGLRTSAINSGSKKSFQSGGRMRRSDKSILCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPLANVFACAVCYEHFVTQQQYKDHLLSKAAAADGHSNDLPPQIIQCFACPHCFLLFSTKDECLKHMSAKNHFHQSLKLGDDKGTARPVSFPSFAKKLLVSLCKDVPFLVKCVACHQTLRSHMELSAHFRVRCRNAGPVAIAEKSITQVAKEFLVRGYCSDCNQVFMDEASTQSHK-NPGHKMSFANSVEESVLLYCHISEGSR-PPCDLHLFN-QPKISSLKRILSSKESSAEDCV-IPTKKVNLGVDSQGGTARVQRQRSTVTAWFCECSRRFPSEDAVEKHVFSANTMCYKCVVCGKVCEDSGVMRLHMSRFHGGAHLNNFLFWCRMCKKELIRKDAIMAHVTEFHSGHRYFYEMDEVEA----AVPSSS-TENHLNADKPPSPIAVVDHSPASSPPRGRWQCRICEDMFDSHECVQQHCASLTSHRFHRYSCAHCRKTFHKVETLCRHCQDEHSGEVRMMYCCGLCD-LIFNKEEAFLSHYTEQHSGDYVFVPEKTKTSIKT-EDDFKIIETSNLLSCGCHESYICKVNRRDDYDRCLQIMLEKGKLWFRCGSCSATAQNLADINTHVCQAHRKVRGDEEQQYVIKCGVCTKAFHNTESAQQHFHRKHAAFQKPVTAHVRADHGSTGQLAASVSHAEKNPRHTS-YQKCSDVERSAEHDVCCQNIEEE-VELPDVDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPLGCKVYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKECDSDDSMGVKGSPV-EELRATEDVELEEAIRRSLEEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0P7-1", "uniprot_id": "ZN451_MOUSE", "id": "Q8C0P7-1", "name": "E3 SUMO-protein ligase ZNF451", "aln": "MGDPGPEIIESVPPAGPEASESTTDENEDDIQFVSEGPLRPVLEYIDLVSSDDEEPSTSHSDENFKCKDYIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIQGHSETEAARQCVDQWLKMPGLRTNAANSGTKRSFQRGGRMWRSEKPILCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPLANSFACAVCYEHFVTQQQYKDHLLSRTAAADGHSNSLLPQIIQCYACPQCFLLFSTKDECLKHMSTKNHFHQSFKLSDNKGTARPISFPSFAKKRLVSLCKDVPFQVKCVACHQTLRSHMELTAHFRVRCQNAGPVAIAEKSITQVAKEFIVRGYCSDCNQVFMDVASTQSHK-NSGHKITLANSVEESVLLYCHISEGSR-PPCDLHLFS-QPKISSLKRILSVKESSAEDCI-VPTKKVNLGVESLGGATRVQRQSPAVTAWFCECRRQFPSEEAVEKHVFSANTMCYKCVVCGKVCEDSGVMRLHMSRFHGGAHLNNFLFWCRTCKKELVKKDAIMAHITEFHSGHRYFYEMDEVEEEEEEAMPSSS-VESHLNTDKPPSPIAVVDHCPANSPPRGRWQCRICEDMFESQECVKQHCMSLTSHRFHRYSCAHCRKTFHKVETLYRHCQDEHDSEIMMKYFCGLCD-LIFNKEEEFLSHYKEHHSIDYVFVSEKTKTSIKT-EGDFKIVETSSLLSCGCHESYMCKINRKEDYDRCLPVLLEKGRLWFRCSSCSATAQNVTDINTHVCQVHRKEKSEEEQQYVIKCGICTKAFQNTESAQQHFHRKHAALQKPTATPGGANRSSTCQLAASASHAEKNLKQPS-SQKHSDVEKGAEHDVRCQNIEEE-VELPDVDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPLSCKVYNYLSRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKECDSDDSSGMKGSPA-EELRATEDVELEEAIRRSLEEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4E5-1", "uniprot_id": "ZN451_HUMAN", "id": "Q9Y4E5-1", "name": "E3 SUMO-protein ligase ZNF451", "aln": "MGDPGSEIIESVPPAGPEASESTTDENEDDIQFVSEGPLRPVLEYIDLVSSDDEEPSTSYTDENIKRKDHIDYQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINCGTKSSFRRGGHTWVSGKPILCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFFSSFACVVCYKKFVTQQQYRDHLFDKEATDDGHNNNLLPQIIQCFACPNCFLLFSRKEECSKHMSGKNHFHQSFKLGDNKGIAHPISFPSFAKKLLISLCKDVPFQVKCVACHKTLRSHMELTAHFRVHCRNAGPVAVAEKSITQVAEKFILRGYCPDCNQVFVDETSTQNHKQNSGHKVRVINSVEESVLLYCHSSEGNKDPSSDLHLLLDQSKFSSLKRTMSIKESSSLECIAIPKKKMNLKDKSHEGVACVQKEKSVVKTWFCECNQRFPSEDAVEKHVFSANTMGYKCVVCGKVCDDSGVIRLHMSRIHGGAHLNNFLFWCRTCKKELTRKDTIMAHVTEFHNGHRYFYEMDEVEG---ETLPSSSTTLDNLTANKPSSAITVIDHSPANSSPRGKWQCRICEDMFDSQEYVKQHCMSLASHKFHRYSCAHCRKPFHKIETLYRHCQDEHDNEIKIKYFCGLCD-LIFNVEEAFLSHYEEHHSIDYVFVSEKTETSIKT-EDDFPVIETSNQLTCGCRESYICKVNRKEDYSRCLQIMLDKGKLWFRCSLCSATAQNLTDMNTHIHQVHKEKSDEEEQQYVIKCGTCTKAFHDPESAQQHFHRKHCFLQKPSVAHFGSEKSNLYKFTASASHTERKLKQAINYSKSLDMEKGVENDLSYQNIEEEIVELPDLDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPLNCKIYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKECDSDDNMGAKNTSIGEEFISTEDVELEEAIRRSLEEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QHV0-1", "uniprot_id": "A0A8M1QHV0_DANRE", "id": "A0A8M1QHV0-1", "name": "", "aln": "----------------------MFEDPEDDVQFVSEAPLRPVLECIDLLSDGDDEDDLPAAN---TIEQQVDRQRAHAVSTLDRLAQQVAVEKQERAEKRKAFKEKMISLQAQGRRELSVSHDNSASGDAKRCVDIWLKMPGLQPGSIYSGSLWKRRSAPPAVRFS-PQSCPVINCGRVYDNIPLLQGHLKRFDHSPCDPTITLKGTAPSIYACLACGEHFCSQETWKQHMQSKLSS-DGHRRSQMYQMIVGFACPSCYFLFNSKDECCKHMNARKHNRQVISLTEEKASAVPVPVPRFAKQRLIALCKDIGFSVRCTVCSQRLNSHMEATAHFNVHCRDGCAIATADQTVADMMKKMAVVGHCISCPEVFLSLDQMQEHKERMKHDVENITLLERALLHYSNHCETRT----------------------NQKRASNEDHS------AKRKRAEDSDSQVKRERKHSNVAWFCECGLRFVEENHAKRHQQAANQIFHKCAVCGKLTGESSIARLHMSRFHGGAHLSNFLFYCRKCKVEMPRMEDIMAHVSASHQGHNYYEEREDSGS------------VIDQISAKPSTSKECEPIRSVSPKKTESWLCRMCEDLFDSEKLVRKHCGDLSSHSFQRFACGHCPQKFFKDSTLRRHCANEHNGDVALRYFCGLCDSMLFDTENEFQVHYDNLHSQDYYRLETSTNHSQNAPEVIVNNSNTSDSQTCLCMGSKKSREERKPVYTNCMKQLAAENKCRYRCRNCAKSAQSYAEMKTHILLKHK----GNGKSFDVVCMICSQSHKDVPSFHAHHHIHHCQAEPCTYSRPDAEEKRASGVNDAEEKRASGVINAE-EKRASGVINAEEKRVSSVMNAEEKRASSVMNAEEKRASSVMNAEEKRASSVINAEEIFPQ--------------------------------------SNVEEAEDVNNAIASGVLDVKKETTVSQDDGEGDD---------------------AKFDEDMKQAVALSLKEARKTADLR-------------------TELEEALRRSLEEF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :.*. . * :: . :: :* *: :.. ** ***::* ****:: **.:**:**: :*:* :**.. :.:* : *: *** ****.**:..: .*: . : . . **:::*.: :** ** *****************:*. . :** .* ::* :*: :::*: .: :: *** .. *:* :*** *::**. *:** ***. ::* :* :.* ::*. * *:..* ***: *::****: * *:*..* : *.**** :***.*:*::. .:* *::::::: ::: : *:* .* :**:. . *.** . *.: . :*.::* *.: .* . *.:* : : . . :.. :***** :* .*: .::* :** : :**.****: :*.: ******:******.****:** ** *: : : ****:: *.**.*: * :: . : **.:. .... * **:***:*:*.: *::** .*:** *:*::*.** : *.* .** *** :**..:: : * ***** ::*: *: * ** : ** ** : .*: * :: * . :**. :* * * .: :*: * .*: : :.: :** *: :**. ::::**: *: : :.: : * *:::.:: * : *.* :*. : : ::. . : .: :. .: .: .. *: : ** . :: .. : *: :: :. . : : * *: ::* *. .: :* ** : . :. .**: ::: ** *: *:.:: * .* .*****:******:", "identical_positions": 277, "similar_positions": 311, "identity": "25.98%" }, { "cls_id": "homologset.agr.MGI:2137913", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1V4-1", "uniprot_id": "LOL2B_DANRE", "id": "A1L1V4-1", "name": "Lysyl oxidase homolog 2B", "aln": "-----MLALWSISFVLLCSWRLSYAQYEHLGFAIAYQEPEQDL---YTPPELPADTPRIQLRLAGEKRKHNEGRVEVFYEGEWGTVCDDDFTIHAAQVICRELGYFEAISWSPSSKYGKGEGRIWFDNVHCKGKEKSLAQCESNGIGVSDCKHSEDVGVVCSDKRIPGFKFVNTLTNNINSLNIQVEDVRIRPILASYRKRIPVTEGYVEVKDGGKWKQICDDEWTQMNSRVICGMFGFPGQKRYNTRVYKMFARRRKPSYWDYTINCTGKEAHLSSCTLG--HTLS---NSTCEEGTPVVVSCIPGRAFAPTPMTGYKKAFRQEQPLVRLRGGAVVGEGRVEVLKNGEWGTICDDNWNLLAATVVCRELGFGSAKEALSGGQLGQGMGPVHMNEVQCSGFEKSVTECSFNMEKDSEGCSHEEDAGVKCNVPAMGFQQRLRLSGGRNPFEGRVEVLVERNGSLVWGTVCGEGWTTMEAMVVCRQLGLGFASNAFQETWYWPGAVNADAVVMSGVRCAGTEMSLSHCLHHG--EYLSCPKGGGRFAAGVSCSETAPDLVLNPQVVEQTTYLEDRPMFMLQCAYEENCLASTSSATPANS------PRRLLRFSSQIHNNGQSDFRPKISRENWVWHDCHRHYHSMEVFTHYDLLSTNGTKVAEGHKASFCLEDSECDEGIEKRYECANFGEQGITVGCWDTYRHDIDCQWVDITDVKPGDYIFQIVINPNYEVAESDYTNNIVKCRCRYDGHRIWMYNCHIGGSFSAETEDTFP---GLINNQVTHR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QQC3-1", "uniprot_id": "LOL2A_DANRE", "id": "F1QQC3-1", "name": "Lysyl oxidase homolog 2A", "aln": "------MAVSSA----LCIFSL-------LVLAQAQSELQQ---------------PKIELRLAGDKRKHYEGRLEVFYNNEWGTVCDDDFSIEAAHVACRQLGFLGAVAWSPSAKFGQGEGRIWLDNVHCTGRENSLAACPSNGFGVSDCRHSEDVGVICNQKRIPGHRFINIMNNNVETLEERVEEIRIRPISS-HLKRIPITEGYVEVKERGKWRQICDEEWTPLNSRVACGMYGFPGEKNYNNKVYRSLSMRKKKNYWGFSVNCTGNEAHVSSCRLG--KALEPKRNGTCGRGLPVVVSCVPGRAFAPSSSIGFRKAYRPEQPLVRLRGGANVGEGRVEVLKNGVWGTVCDDNWNLKAATVVCRELGFGSAKEALTGAKLGQGMGPVHMNEVECSGFEKSLTDCYFNN--DALGCSHEEDAAVRCNVPAMGFQKRIRLSGGRNPFEGRVEVLAEKNGSLVWGTVCSENWGIIEAMVVCRQLGLGFASHAFQETWYWAGDANADNVVMSGVRCSGTEMSLPQCLHHG--KHINCPKGGGRFAAGVSCSDTAPDLVLNAQLVEQTTYLEDRPMYALQCALEENCLSSTARKNDHSS------YRRLLRFSSQIHNVGQSDFRPKLGYHAWTWHECHRHYHSMEVFTHYDLLSLNGTKVAEGHKASFCLEDTHCDEGISKRYHCANFGEQGITVGCWDTYRHDIDCQWIDVTDVKPGDYIFQVVINPNYDVAESDYTNNVMKCKCRYDGYRIWTYSCHIGGSRSSD-MDEYS---GMSNQLNHLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B5DF27-1", "uniprot_id": "LOXL2_RAT", "id": "B5DF27-1", "name": "Lysyl oxidase homolog 2", "aln": "MEIPFGSCLYSCLALLVLLPSLSLAQYESWPYQLQYPEYFQQPPPEHHQHQVPSDVVKIQVRLAGQKRKHNEGRVEVYYEGQWGTVCDDDFSIHAAHVVCREVGYVEAKSWTASSSYGPGEGPIWLDNIYCTGKESTLAACSSNGWGVTDCKHPEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIRPILSAFRHRKPVTEGYVEVKEGKAWKQICDKHWTAKNSHVVCGMFGFPAEKTYNPKAYKTFASRRKLRYWKFSMNCTGTEAHISSCKLGPPMFRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRKAYKPEQPLVRLRGGAQVGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGTAKEAVTGSRLGQGIGPIHLNEVQCTGTEKSIIDCKLNT--ESQGCNHEEDAGVRCNIPIMGFQKKVRLNGGRNPYEGRVEVLTERNGSLVWGNVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIFANKVIMSGVKCSGTELSLAHCRHD---EEVVCPEGGVQYGAGVACSETAPDLVLNAEIVQQTAYLEDRPMALLQCAMEENCLSASAVHTDPTRG-----HRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTYYDLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQWIDITDVPPGDYLFQVVINPNYEVPESDFSNNIMKCRSRYDGYRIWMYNCHVGGAFSEETEQKFEHFSGLLNNQLSVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58022-1", "uniprot_id": "LOXL2_MOUSE", "id": "P58022-1", "name": "Lysyl oxidase homolog 2", "aln": "MELHFGSCLSGCLALLVLLPSLSLAQYEGWPYQLQYPEYFQQPAPEHHQRQVPSDVVKIQVRLAGQKRKHNEGRVEVYYEGQWGTVCDDDFSIHAAHVVCRQVGYVEAKSWAASSSYGPGEGPIWLDNIYCTGKESTLASCSSNGWGVTDCKHTEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIRPILSAFRHRKPVTEGYVEVKEGKAWKQICNKHWTAKNSHVVCGMFGFPAEKTYNPKAYKTFASRRKLRYWKFSMNCTGTEAHISSCKLGPSVTRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRKAYKPEQPLVRLRGGAQVGEGRVEVLKNGEWGTICDDKWDLVSASVVCRELGFGTAKEAITGSRLGQGIGPIHLNEVQCTGTEKSIIDCKFNT--ESQGCNHEEDAGVRCNIPIMGFQKKVRLNGGRNPYEGRVEVLTERNGSLVWGTVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIFANNVVMSGVKCSGTELSLAHCRHD---EEVACPEGGVRFGAGVACSETAPDLVLNAEIVQQTAYLEDRPMSLLQCAMEENCLSASAVHTDPTRG-----HRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTYYDLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQWIDITDVPPGDYLFQVVINPNYEVPESDFSNNIMKCRSRYDGYRIWMYNCHVGGAFSEETEQKFEHFSGLLNNQLSVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4K0-1", "uniprot_id": "LOXL2_HUMAN", "id": "Q9Y4K0-1", "name": "Lysyl oxidase homolog 2", "aln": "MERPLCSHLCSCLAMLALLSPLSLAQYDSWP---HYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA--ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG--EDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTG-----YRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2C9-1", "uniprot_id": "Q9W2C9_DROME", "id": "Q9W2C9-1", "name": "", "aln": "MCAIEDRKVLKMGLTLVCLTLLAIHMADAVVQHRSLEDARQERQRLVHRYTKVLNKEEGAIRLVGGD-NEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARRRFWMDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVCYPP-------ENALIP-MATPIIRDEDLPKYPIHS-------------------------------------------------------------------------------------------------------------------------------RSRLYVRLRGGRSRIEGRVEVS------------------------------------------------------------------------------------------------LDGGR------------------WGSVCADGWSLLEANVVCRQLGLGYASEAFQTDFFGG--FNVSRPVLSGSECYGNETELADCLHHDASQGIISCHGNRQHVAAVICDYIAPDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAAAINAGNADFRPFKEKSQWEWHMCHMHFHSMEVFATFDIFNLRGIKVAQGHKASFCLEDSNCLPGVAKKYNCANYGDQGISINCSDVYLYNLDCQWVDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIYTANFARVQNCQLGRP-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * . :**.* . :. **.:** ::.:**:****:: *.: **::*: :: *. :* .. :*:**:.* *.* *. * :* * .**. * .**:* * : : . : *:: .* : .: ****** ****** *.*** ** **.:.* :** *********:**.*** :: . ::** .* *.* .*..* *. : : . .*. :. *.* *. *****:: ::**::****** :*** ****:: : ****:*:: * *::**** * ** ** *:******: :*::. .* ***:**********:.* .: * *.***:*:***::.* * * :::****:*:**: ** *::::.***::.*.* :: ** * * . .*::* . ", "identical_positions": 181, "similar_positions": 131, "identity": "23.03%" }, { "cls_id": "homologset.agr.MGI:2138069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCB1-1", "uniprot_id": "HMGN3_MOUSE", "id": "Q9DCB1-1", "name": "High mobility group nucleosome-binding domain-containing protein 3", "aln": "MPKRKSPENTEGKDGTKLTKQEPTRRSARLSAKPVPPKPESKPRKTSAKKEPGTKISRGAKGKKEEKQEAGEEGTAPSANGDTKVEEAQR-----------------------TESIEKEGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15651-1", "uniprot_id": "HMGN3_HUMAN", "id": "Q15651-1", "name": "High mobility group nucleosome-binding domain-containing protein 3", "aln": "MPKRKSPENTEGKDGSKVTKQEPTRRSARLSAKPAPPKPEPKPRKTSAKKEPGAKISRGAKGKKEEKQEAGKEGTAPSENGETKAEEAQK-----------------------TESVDNEGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66H40-1", "uniprot_id": "HMGN3_RAT", "id": "Q66H40-1", "name": "High mobility group nucleosome-binding domain-containing protein 3", "aln": "MPKRKSPENAEGKDGAKLTKQEPTRRSARLSAKPVPPKPEPKPRKTSAKKEPGTKINRAAKGKKEEKQEAGKEGTAPSANGDTKAEEVLS-----------------------TNASH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QH74-1", "uniprot_id": "E9QH74_DANRE", "id": "E9QH74-1", "name": "High mobility group nucleosome-binding domain-containing protein 3", "aln": "MPKRKSPEGAEAKDATKVTKHEPTRRSERLSSKPAPPKPEPKAKKPAAKKPSNDKAVKEKKGGAKGKKEE--KDSVPTANGETKPEEICVSRSSVSVSSWRSSAPSFLSIRGQSESVRVKGN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.:*.**.:*:**:****** ***:**.*****.*.:*.:*** .. * : ** : *:* :.:.*: **:** ** ::: ", "identical_positions": 47, "similar_positions": 28, "identity": "38.52%" }, { "cls_id": "homologset.agr.MGI:2138080", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M9G7-1", "uniprot_id": "UTP25_RAT", "id": "Q5M9G7-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRRSRGRSQLLSTMTKKQKKHLRDFGEEHPFYDRVSKKEVKPQICQLSESSDS-----SHSESESESEQEHVSG-YHRLLATLKNISEEEEEEEEEEEEEEEDKEE-----VDDSAVGDSEMNGEDGGED------VRVEETAESSETQDHMSLADNSKGK-DGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEESGGSYSQRTSQDPFQHHINKELQEKEIQAAASSPAATQQLKWPVLGHLVFSSKFQKMETFKPPKDIDLKSLHLQKPLESTWAKTNSQFLSGPGPQKSSSCFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRR-------RTQKLGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVNFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCVNAQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAQD--LASVIDARFHFFINKILPQYRDAV--MSHTLIYVPSYFDFVRLRNYFKKEE-LNFTHICEYTQRSGVSRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYAHFYSEVCNMLRATSR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKSVHLFITGEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTT6-1", "uniprot_id": "UTP25_MOUSE", "id": "Q8BTT6-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRRNRGRSQMLSTMTKKQKKHLRDFGEEHPFYDRVSKKEAKPQICQLPESSDS-----SHSESESESEQEHVSG-YHRLLATLKNVSEEEEEEEEEEEEEEEEEEEEEEEEEDDSAVGDAEMNEEAGSEDGSVGEAAVSEAAEEAAETQEHMSLADNSKEK-DGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEDSGGSCSQRPSQDPFQQHVNKELKEKEIQAAASSPPATQQLKWPVLGHLVFSSKFQKTETFKPPKDIDLKLLHLQKPLESTWAKTNSQFLSGP--QKSNSSFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRR-------RSQKLGVGEDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSVELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCINAQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAQD--LSSVIDARFHFFINKILPQYRDAV--MSHTLIYVPSYFDFVRLRNYFKKEE-LNFTHICEYTQKSGISRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEVCNMLRATSR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKNVHLFVTGEK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CQ4-1", "uniprot_id": "UTP25_HUMAN", "id": "Q68CQ4-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRGSRSQSQLLNTLTKKQKKHLRDFGEEHPFYDRVSRKEAKPQICQLSESSDS-----SDSESDSESEPQQVSG-YHRLLATLKNVSEEEEEDEEEEEEE-------------DSIVDDAEMNDEDGGSD----VSVEEEMAAESTESPENVALSADPEGKEDGEEPPGTSQTSPEEFTDAKHESLFSLETNFLEEESGDNSSLKASQDPFLQHVNKELKEKAIQAVATNPKTTHELKWPILGQLFFSSKFQKLETFKPPKDIDLKSLHLQKPLESTWTKTNSQFLSGP--QKSSSPFTPLQKELFLIMNSYRDLFYPERTALKNGEEIRHVYCLHVINHILKANAQVLGNNSRR-------RSQKFGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKYCVNMQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAEN--LASVIDARFNFFVNKILPQYRDAV--MSHTLIYIPSYFDFVRLRNYFKKEE-LNFTHICEYTQKSGVSRARHFFLQGEKQFLLFTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEICNMLRATNR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSNKNVHLFITGEK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PEH4-1", "uniprot_id": "UTP25_DANRE", "id": "Q6PEH4-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRR-RGK-QEIDNLTKKQKKHLKEFGEQHPFHDKVVERPEKTQILRLPDSPQR-----PEPDSEDDSDAEQPSA-YQKLLSTMIQGDEDDVESEDEESEEEDNEEE-------AEVEGDSEEEVEDTDEE----DGNDAEEVLEDKVEETSDKLQKKHPEKTNGDVEENEEAEMEGEFTDKKNEAAFCLETNMPAEGEENTAQQEQDEDMFVKHQEIELSEEEVGRISQGSKVKTQVKWAKLGVLQCMCPLERFPAIGQASSAPLPPIH--KTLEANWHLLNLPFGAAT-------DVTELQKEMLGLMGTYRDLYLANLSPLKEAKEVRSAYCLHALNHVLKANSRVLRNNAKL-------KESKNG---DEDFRDQGLTRPKVLILVPFRDGALRVVQTFMTLLEP---KGKK-TDASNKKRFKEEYGEETDEKPPNLQRPDDYHAVFSGNIDDHFRIGMSILRHSMRLYAPFYSSDIIIASPLGLRTVLGAEGEKKRDHDFLSSIELLIVDQADVFLMQNWEHLLHVLEHLNLQPLDSHGVDFSRVRMWNLNNWAAYYRQTLVFSAIQEPQITNILTKHCHNYRGQVCSKTIP--KIGSICQVLVQLPHVFQMFHSDS--FMD-QDARFQFFVDKILPQYRDSV--MSHTFIYVPSYFDFVRLRNYLKKED-VSFANISEYSQRSEVSRARHYFQKGEKQFLLFSERFHFYKRYTIKGIHNLIFYGLPTYPHFYSEVCNMLQAGVRE--GGASVSFTCTALYSRYDVHRLAAITGADRAAQMLQSKKTTHLFITGEEKST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1G1-1", "uniprot_id": "Q9W1G1_DROME", "id": "Q9W1G1-1", "name": "Digestive organ expansion factor homolog", "aln": "MKQKHSKNRAKPYKKPTPARRNER--FSKNYSFIQRSKQMEESHRRERMPTAPKQEYEPVAELLPEIQDDVDETEF-YKKLITGVNNIPTSDILRSKAEKEE-----------------------------------------------DHVIPVPRKIKPKKEKRSEQLGVDLEIYNSFS------------------------KRFDFELSTDNINDLIARKDVKTIKRNWSALGNVRFDIPRLTEDFKEPDCSEPKDIASTEDLQKLEVKASICANAKLP----------------LTALQSQLFYIANNYQDIYYPHRTHG-NAEDIRYVYCLHALNHMLKVRSLILRNNEKVSALAKSQKMSPNEISIPESFRDQGLKRMKVVFVVPFRESALRIVNILGDLLFGSQDDQARKTSIANYERFLGDYSGNTIYFPKTNPKPMDYEQTFSGNTDDNFKLGIRFTKKTMSLFSDMNASDMLIASPLGLRMLVT---DKESDFDFLNSIELLIIDQAELFLAQNWENLLHSLDHLHLQPQKLPDTNCQRVRTWCLSGASSFYRQTLFFSSHELPEFRAVFNSKCNNYQGKVRDSNLV--EHGDIRNVLTPIHQVFRLINCSS--VETTFDDRFQYFVKNIMPQFSKPG--FSHCMLYVPSYFDYVRIRNHFKTEM-VSFVQINEYTKKEKISRARDIFFHSGASVLLYSERAHFFRRTRIKGIRNLIMYQPPNFPHFYSEIINLMLKTNQNPRDGFGDEMSVSILYTKYDLLSLSNIVGSENAAKLTSGQKDSYLFSTKT----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40498-1", "uniprot_id": "UTP25_YEAST", "id": "P40498-1", "name": "U3 small nucleolar RNA-associated protein 25", "aln": "MSDSSVREKNDNFRGYRKRGRQELRKIKRSSARTEGGSTETLEDVAEDIDHRSDED--EVSDVDSGDDFDIEDEEGKKEKVYDALLTILKSEHPEPKRRRRE----------------------------------------------ADESNKAPAEVGEDEHENTEHGPVDDQLEIENGLLGNHEDDNDDDSSGDEKDIDSEDEQDPFESHFNQVPEKFVDKLSNAFKTKSVKYKSVKGSLSDSESYIYAKPVVIGEEALVESPYRSSSIYSYFLKQRLKVQNGLLDKK-----TDPLTALQKKLVDPMFQYKDILYEYDSYEKDEDEYRDLYALHVLNHIYKTRDRILKNNQRLQ------------DNPDTEHLDQGFTRPKVLIVVPTREVAYRVVDKIIS--------KSGIDQVDKKGKFYDQFRDDS---LPPKSKPKSFQHIFRGNTNDFFVVGLKFTRKAIKLYSNFYQSDIIVCSPLGIQMILENTDKKKRQDDFLSSIELMVIDQLHSIEYQNISHIFTIFDHLNKIPDQQHEADFSRIRMWYINEQAKLFRQTMVFTKYISPAANSLINGRCRNMAGRWKNHKVIGSENSSIGQSGLKIRQIFQRFDIIGNSIIEEPDYRFKFFTSVIIPGIVKSTGYEDGILIYIPDYTDFIRIRNYMKEKTTILFGDINEYSSQRQLNANRSLFQQGRLKVMLYTERLHHYRRYEIKGVKSVVFYKPPNNPEFYNEVVRFIGKNAFLG-NTDLNISTVRCIYSKLDGLSLERIVGTKRAAVLSHAQKEIYEFK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : . ::. : .. . : . : .. .. . : : :. . .:: : .: . . .* : . . . . : .: : : .:: : .* **.::. *:*: : : .: * *.**.:**: *.. :* ** : .. ***:.* **:::** *: * *:*: : : :* :: :. :* .:. * ** :* * :*: : :::: *:: : **:::.****:: :: .*: : ***.*:**:::** . ** .::: ::*:: * . .: .*:* * :. : :***:.* . ::. * * *: .: ..* : : ::*: :. . . * **::* . *:* .. . ::*:*.* *::*:**::* : : * .* **:.: :. * * :. ..:* :** *.::* ***::.:::* *. ..**.*: .:: : :*:: * * :.* ..** : . * : * ", "identical_positions": 110, "similar_positions": 210, "identity": "13.66%" }, { "cls_id": "homologset.agr.MGI:2138133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJR8-1", "uniprot_id": "LRC59_RAT", "id": "Q5RJR8-1", "name": "Leucine-rich repeat-containing protein 59", "aln": "---MTKTGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQQAKEAKERELRKREKAEEKERRRKEYDAQKAS--KREQEKKPKKETNQAPKSKSGSRPRKPPPRKHNRS----------WAVLKGLLLLLLLCVAGGLVVCRVTGLQQQPLCTSVNAIYDNAVQGLR------HHEILQWVLQTDSQQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922Q8-1", "uniprot_id": "LRC59_MOUSE", "id": "Q922Q8-1", "name": "Leucine-rich repeat-containing protein 59", "aln": "---MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQQAKEAKERELRKREKAEEKERRRKEYDAQKAS--KREQEKKPKKEANQAPKSKSGSRPRKPPPRKHTRS----------WAVLKVLLLLLLLCVAGGLVVCRVTGLHQQPLCTSVNTIYDNAVQGLR------HHEILQWVLQTDSQQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AG4-1", "uniprot_id": "LRC59_HUMAN", "id": "Q96AG4-1", "name": "Leucine-rich repeat-containing protein 59", "aln": "---MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQRAKEAQERELRKREKAEEKERRRKEYDALKAA--KREQEKKPKKEANQAPKSKSGSRPRKPPPRKHTRS----------WAVLKLLLLLLLFGVAGGLVACRVTELQQQPLCTSVNTIYDNAVQGLR------RHEILQWVLQTDSQQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWG1-1", "uniprot_id": "LRC59_DANRE", "id": "Q6NWG1-1", "name": "Leucine-rich repeat-containing protein 59", "aln": "---MNKG--KIENIKDKIDGNELDLSLSNLTEVPVKELAAFPKATFLDLSCNNLITLTPEFCSLTHLIKIDLNKNQLVCLPEEIGQLVNLQHLDLYNNKLKMLPIGFSQLKSLKWLDLKDNPLEPTLAKAAGDCLDEKQCRQCASRVLQHMKVLQEEAEKELERRLLKEREQEKKKEAKQREKEAREKEAQKKKKAEEKERKRKEYQAQVAAVAAQEQQKKKKEEKKKKAAQNQGKKAAPESVPKAKRSICS-----LFFSLLLKLVLLLVIGVSSVVAVCQLTELRKEAFCIPLNVHFEETVRWAQ------GLDVVQQVIQKMSDLRT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT05-1", "uniprot_id": "Q9VT05_DROME", "id": "Q9VT05-1", "name": "Leucine-rich repeat-containing protein 59", "aln": "MPKPGDKAKVKVNVKERVVDETCDLSLSELSEIPVREIASFKRVTVLDLSSNRLVNLGKNFSILTRLVRLDLSKNQIKFLPEDFGQLEQLRHLDLYNNCLEHLPISFGQLRRLRYLDLKGNPLTPAWEKIVGCCSTQKDCQQAAKNTVSICANYKPEFIERERLAAQESQKMAGAGDSSANAVQTNGGAAGGKKSTKPNNKKAKAKKLAGGGDNELTIKPVNAVGSGGSGAIALGSKSTQKNNQKKKNSKGDSWLNLLSRAALSSLVSFLVLFIINLLIIYMIMFKNPDIADKLVEYIPHQYRDWILTKTEIFRLRVTDWISEFRTPPEEH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::::: .: *****:*.*:**:*:*:: :.*.****.*.* .* :*. **:*:::**.**:: ** ::*:* :*:**** ** * **:.*.**: *::****.*** *. * .* * :*:*:*.*...:. : : .. . .:: ::. . ::. ::.:: :::: * . .. : *.:. * ..* : * *: :*:: : . : : . : :: .: : : : : : ", "identical_positions": 68, "similar_positions": 106, "identity": "20.54%" }, { "cls_id": "homologset.agr.MGI:2138143", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499V8-1", "uniprot_id": "SARG_RAT", "id": "Q499V8-1", "name": "Specifically androgen-regulated gene protein", "aln": "MPKRELWPAGSCSEPVTHIGSCGSMMSTTSTHSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPQSFRALPTTTQRAPQGKPEARDTQQVPVPVPKRAAQSSGPPESPSPGLRSGSYSLPRNLHLGRSQNLRKSATQTNS-VSEAPEVFLEEPKKGQTRQG--AKTIQPPAPSQEGTPDLNTVLIPPPEAFQDITSKKAEGESPPKKPGEQTHRPQGHILERSPHSQKKADMSSETMTHKATEKGWTEGPQRPQQPPTQPSQNTQAEEPSLPSGVKPNIQQSLLTATKPRRLPPNIVLKSSRSSFHSHPQNWLSNHTEAT--DSGPVS-SLQEQRKARREALEKLGLPQDQDDPSLPVNKHTGSFKVKEAQAQTSSQARAPAQPASPALVRGTASVAEKASSVKAITPLDSLSKGWIPAQETPPGKVGAAKSMPIPIPKASKENSSLTQSKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEK-DPGGQTSTSLGKSPFLDKVSSSVFRNSRPRPASLGMGKDFAGIQGGKLVGLEQGQCSQQPSFKGQSHDKLPRPPCVSVKISPKGIPDGHRREALKKLGLLKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BI29-1", "uniprot_id": "SARG_MOUSE", "id": "Q8BI29-1", "name": "Specifically androgen-regulated gene protein", "aln": "MPKRELWPAGLCSEPVTHIGSCGDMMSTTSTRSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPRSFRALPTATQQAPQGKPEATDIQQVPV--PKRVAQPSCPPESHSLGLRAGSYSLPRNLHLGRSQNLRESATQANSPVSEASEVFLEEPEKGQTSQGAKAKTIQPPAPSQKGTLDLSTVLIPPPEAFQDIRPKESGEESPPKKPGEQTHTPQVHSLERSPHSQKKVEMSSETVSHKATEKGWTEGLQQPQQPPAQSSQPTKAEELSLPSGVKPSIQQTPLTASKARKLPPNIVLKSSRSSFHSHPQNWLSNHTEAT--DSGPVS-SLQEQRKARREALEKLGLPQDQDDPSLLVNKHTSTLKVREAQPQTPSQARAPARPASPALVSGTASAAGKVSPKKAVAPMDSLSKGWIPTQETPPGKVAEAKSMPIPIPKTLKENSSRTQPKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEKKDPSCQTSTSLGKSPFLDKVSPSAFRNSRPRPASLGMGKDFAGIQGGKLVGLEQDQCSQQPSFKGQSYDKLPRPPCISVKISPKGIPDGHRREALKKLGLLKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BW04-1", "uniprot_id": "SARG_HUMAN", "id": "Q9BW04-1", "name": "Specifically androgen-regulated gene protein", "aln": "MPERELWPAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTDESEPATTPRGFRALP-ITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQS--SQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTP---SSSQEREQTPSEAMSQKAKETVSTR-YTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALA-QAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLS-TEK-DASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFAGIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1ND22-1", "uniprot_id": "A0A8M1ND22_DANRE", "id": "A0A8M1ND22-1", "name": "", "aln": "MPISDMRQDGNGLDTMGEIDSNGSCDSVVSFNSCFSDESLEYLSAEEKACLMYLEETIQSLDTEDDSGLSNDES----------------LQLPARGNVANKAAHISASIKLNKLPSQDMPKSRSEGLYSS------GSFEQNSEILNYMVPTPFVLANHNSKLQTRAASQKNTASKVTSESIQIHQEAPRVPPEVNVVVIPPPRKAKSSKEIK---------------------------KEQQKNLQSENVAHRG-PLSYEALVQLRKSASMRKTNATEANYSTKKDINGKTSESQTIFKPAPPPVAPKPKKKLNQEGASGTNKDSSMAYSGEK----------LMNPEKVRVEALCKLGLLKEDAKICKQLKQSQS-----KPANQASSEHLANSIPARPEEQ----------------------------------------------INQTVQRSSPLHQRSASDLLTSSSHAQHANMTSTAKSATLERTGMGLS-------------------------GSNTNAVSQSHRPRSSTMATNKDTQ---------MDANESTPRKPFNILS----SRTKVFSVPVPSIGK---DRREALRKLGLLKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: * :.: .:.* .. * .* .* **.* ::**:*** **::**:** **::* *****.*** * : . .. *:. . ** :. . . .*: :. .. . . ..: :. . ::. * . . . ::..*:****. :. : .::: : ** ::::. : .. .: :.*: . . . . : . . :.*: * .:.. . :. :: * : .*.* *** **** ::: . :.: . :. * * . : ** * * :: : .*. ... ** .. . . ** ****:*:*** .. : :. :. ***.:::. .** :: :.: : .:: * .*. .** :.. * .*****:******:", "identical_positions": 98, "similar_positions": 159, "identity": "16.04%" }, { "cls_id": "homologset.agr.MGI:2138151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88867-1", "uniprot_id": "KMO_RAT", "id": "O88867-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MASSDTEGKRVVVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVANFMRG--RSINLALSYRGRQALKAVG--LEDQIVSKGVPMKARMIHSLSGKKSAIPYG-NKSQYILSISREKLNKDLLTAVESYPNAKVHFGHKLSKCCPEEGI----LTMLGPNKVPRDITCDLIVGCDGAYSTVRAHLMKKPRFDYSQQYIPHGYMELTIPP-------KNGEYAMEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMSFEEFEKLPTH-SDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKS-RCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMVAFTR-IRYHEAVLRWHWQKKVINRGLFVLGSLVAIGSAYILVHHLSPRPLELLR------SAWTGTSGHWNRSADISPRVP--WSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WN4-1", "uniprot_id": "KMO_MOUSE", "id": "Q91WN4-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MASSDTQGKRVAVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVAKSARG--RSINLALSYRGRQALKAIG--LEDQIVSKGVPMKARMIHSLSGKKSAIPYG-NKSQYILSISRENLNKDLLTAVESYANAKVHFGHKLSKCIPEEGV----LTVLGPDKVPRDVTCDLVVGCDGAYSTVRAHLMKKPRFDYTQQYIPHGYMELTIPP-------KNGEYAMEPNCLHIWPRNAYMMIALPNMDKSFTCTLFMPFEEFERLPTR-SDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKS-HCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNNLSMCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQKLLDKFLHAIMPSTFIPLYTMVAFTR-IRYHEAVLRWHWQKKVINRGLFVLGSLIAIGGTYLLVHHLSLRPLEFLRR-----PAWMGTTGYWTRSTDISLQVP--WSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15229-1", "uniprot_id": "KMO_HUMAN", "id": "O15229-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRG--RSINLALSHRGRQALKAVG--LEDQIVSQGIPMRARMIHSLSGKKSAIPYG-TKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGM----ITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPP-------KNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTS-NDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS-HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSR-IRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQISNLISR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RLY6-1", "uniprot_id": "KMO_DANRE", "id": "Q1RLY6-1", "name": "Kynurenine 3-monooxygenase", "aln": "------------METAFSHPPQSSSSKRKVIAVVGGGLVGSLNACFLAKRGFDVEVYESREDIRQAKVVKG--RSINLALSHRGRQALKHVG--MEDKIISKGIPMHARMIHNVNGKRSPIPYG-KKGQYILSVDRANLNKELLTAAEAYPNTRLNFNHKLHDWSPKTGT----MTFIGSDGQKTETQADLIVGCDGAFSAVRKQFLRQSRFNYSQTYIPHGYMELTMPP-------KDGDFAMEPNYLHIWPRNTFMMIALPNLDRTFTCTLFMPFEDFEKIRTG-DELLRFFHKYFPDSVPLIGVEALKQDFFRLPAQAMVSVKCCPYHLFE-KCVLMGDAAHAVVPFYGQGMNAGFEDCLVFDEIMDQFNENLVAVLQEYTRVRVPDDHAIADLAMYNYIEMRAHVNSKYFIFRKYLDNLLHFFMPKTIVPLYTMVTFTR-TRYNDAVNRWHWQNKVITRGLWLCGFVSAAGGTYVLVKNSHKLP-------------SISAEQLWTRILALKLF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z746-1", "uniprot_id": "KMO_DROME", "id": "A1Z746-1", "name": "Kynurenine 3-monooxygenase", "aln": "MSPGIVSQEVNGRQEPTEAARDERHGRRRRVAVIGAGLVGSLAALNFARMGNHVDLYEYREDIRQALVVQG--RSINLALSQRGRKALAAVG--LEQEVLATAIPMRGRMLHDVRGNSSVVLYDPINNQCLYSVGRRQLNEVLLNACDKLPNIRCHFEHKLTSANLREGS----MEFRNPAKEAVAAHADLIVGCDGAFSSVRQNNVRLPGFNYSQEYIETGYLELCIPS-------KSGDFQMPANYLHIWPRNTFMMIALPNQDKSFTVTLSMPFEIFAGIQNQ-NDLLEFFKLNFRDALPLIGEQQLIKDFFKTRPQFLVSIKCRPYHYAD-KALILGDAAHAMVPYYGQGMNAGMEDVTLLTDILAKQLP-LDETLALFTESRWQDAFAICDLAMYNYVEMRDLTKRWTFRLRKWLDTLLFRLFPG-WIPLYNSVSFSS-MPYRQCIANRKWQDQLLKR-IFGATFLAAIVTGGAIYAQRFL---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38169-1", "uniprot_id": "KMO_YEAST", "id": "P38169-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------------MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYG-LHGEAINSINRSVLNNSLLDELEKS-TTELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGNFAIAPDHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESLVCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTEYTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKLDALFSIIMKDKWIPLYTMISFRSDISYSRALERAGKQTRILKFLESLTLGMLSIGGYKLFKFLTRERS-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.::*.****.* * ::: . .: :*: *:* * . :*****:* ** .** :. :.:: :**:.**:*.: *. . *. :.: : *:.* **: ** : . . :* *:* . . : . *:::*****:*:.* : : ::::* *: *:** :*. .*:: : .: ******: :*:***.* : :** *: . : : : . . : *: * * : ::. . : *: : ::.::* .:. :.:::******:**::*****.*:** :: :: : : ::. * * :* :*: ** ** .. * ::: :: :: :: :***. ::* * .: . * :::. : : : ", "identical_positions": 102, "similar_positions": 151, "identity": "19.43%" }, { "cls_id": "homologset.agr.MGI:2138153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQ79-1", "uniprot_id": "TXND9_MOUSE", "id": "Q9CQ79-1", "name": "Thioredoxin domain-containing protein 9", "aln": "MEGNGSVDMFSEVLENQFLQAAKLVEN--------HLDSEIQKLDQIGEDELELLKEKRLAALRKAQQQKQEWLS----KGHGEYREIGSERDFFQEVKESEKVVCHFYRDTTFRCKILDRHLAILAKKHLETKFLKLNVEKAPFLCERLRIKVIPTLALLRDGKTQDYVVGFTDLGN-TDDFTTETLEWRLGCSDVINYSGNLMEPPFQSQKKFGTNFTKLEKKTIRGKKYDSD-SDDD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K581-1", "uniprot_id": "TXND9_RAT", "id": "Q8K581-1", "name": "Thioredoxin domain-containing protein 9", "aln": "MEGNGSIDMFSEVLENQFLQAAKLVEN--------HLDSEIQKLDQIGEDELELLKEKRLAALRKAQQQKQEWLS----KGHGEYREIGSERDFFQEVKESEKVVCHFYRDTTFRCKILDRHLAILAKKHLETKFLKPNVEKAPFLCERLRIKVIPTLALLRDGKTQDYIVGFTDLGN-TDDFTTETLEWRLGCSDVINYSGNLMEPPFQSQKKFGTNFTKLEKKTIRGKKYDSD-SDDD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14530-1", "uniprot_id": "TXND9_HUMAN", "id": "O14530-1", "name": "Thioredoxin domain-containing protein 9", "aln": "MEADASVDMFSKVLEHQLLQTTKLVEE--------HLDSEIQKLDQMDEDELERLKEKRLQALRKAQQQKQEWLS----KGHGEYREIPSERDFFQEVKESENVVCHFYRDSTFRCKILDRHLAILSKKHLETKFLKLNVEKAPFLCERLHIKVIPTLALLKDGKTQDYVVGFTDLGN-TDDFTTETLEWRLGSSDILNYSGNLMEPPFQNQKKFGTNFTKLEKKTIRGKKYDSD-SDDD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGV8-1", "uniprot_id": "PHLP3_DROME", "id": "Q9VGV8-1", "name": "Phosducin-like protein 3", "aln": "---------MANILENQLFTAAKTIEQ--------QLDQQLDRLDNLDSDDLKVLREQRLREMKDLNNKKQEWLR----NGHGTYTELADEKEFFEMSKKSPNIVCHFYRDSTERCKIVDMHLKILAAKHVEAKFCKVNAEKTPFLTQRLRIKVIPTIALVKDSKTKDFIVGFTDLGN-CDDFATEMLEWRIAHSGAIDYKGDLMQPPDVKRK----PFINRPQKTIRGG-YDSDDSDIDLDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04004-1", "uniprot_id": "PLP1_YEAST", "id": "Q04004-1", "name": "Phosducin-like protein 1", "aln": "-MEDKLDRYYTNVLSNAEKDKHTTVDSDDKSSGEENLDELLNELDRELDEDHEFLSAYRSERLQQISDHLKQVKKNVEDDGYGRLQCIDNEADAIQICTKTTMVVIHFELETFGKCQYMNEKLENLAKRYLTTRFIKVNVQTCPFLVNKLNIKVLPFVVGYKNGLEKVRYVGFSKLGNDPNGFDIRRLEQSLAHSGVIEDTFEIRKHSSVNTERFASTNHDRS---------ESD-SDLDI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*.: . ::. :**. ::.**. .:: : * * ::. .:: :: .*:* : .* : :: .:: :* ** :: :*: :: :* *: ::: ::* * *.:. *** ::*.***:* :. ::. : ***:.*** :.* . ** :. *. :: . :: : . . : . :** ** * ", "identical_positions": 42, "similar_positions": 83, "identity": "17.28%" }, { "cls_id": "homologset.agr.MGI:2138162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XS8-1", "uniprot_id": "ST17B_RAT", "id": "Q91XS8-1", "name": "Serine/threonine-protein kinase 17B", "aln": "MSRRRFDCRSISGLLTTTPQTP----MKTENFNNFYTLTPKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYETATEIILVLEYAAGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQQ---WDFGSLFHPEETSESSQ-----------------------------------------TQDLSLRSSEDKTPKS-CNGSCGDRE-----------------------------------------------------DKENIP--------------------EDDSLLSKRFRFDDSLPSPHELVPDLFC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG48-1", "uniprot_id": "ST17B_MOUSE", "id": "Q8BG48-1", "name": "Serine/threonine-protein kinase 17B", "aln": "MSRRRFDCRSVSGLLTTTPQTP----IKTENFNNFYTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQQ---WDFGSLFHPEETSGSSQ-----------------------------------------IQDLTLRSSEEKTSKSSCNGSCGARE-----------------------------------------------------DKENIP--------------------EDGSLVSKRFRFDDSLPSPHELVPDLFC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94768-1", "uniprot_id": "ST17B_HUMAN", "id": "O94768-1", "name": "Serine/threonine-protein kinase 17B", "aln": "MSRRRFDCRSISGLLTTTPQIP----IKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQ---WDFENLFHPEETSSSSQ-----------------------------------------TQDHSVRSSEDKTSKSSCNGTCGDRE-----------------------------------------------------DKENIP--------------------EDSSMVSKRFRFDDSLPNPHELVSDLLC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHT7-1", "uniprot_id": "DAPKR_DROME", "id": "Q0KHT7-1", "name": "Death-associated protein kinase related", "aln": "MFTEKGIFPIGDGLLDVDADRLKGLLVSCPDINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCEGEDNIVNLNAVHETRSDTALLLELATGGELQ--TILDNEECLTEAQARHCMREVLKALKFLHDRSIAHLDLKPQNILLAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNATGCLDHIWLKDDCSLDRQIYLQPQSDAEEEEEEDVDDDVEDEEEEEQVEEEEEETQNVEEPTTEAPQQQQQPVQQHQLAKSGQIHSKPTHNGHHRANSGGSISKIPIATSKLQSTPSSETTTAIHTLTSNSNGHVHKPTQIVTPTRRASDSDKENTYTATFVKKPVATIQLGSSNGIEDATVVATLTLFPDAPTTPKVIRKTPTGESNGSATSVKALVKKFQLEDSSGSAVARRSGGAVTSSSGLHSPTTTSVRLNSIRRASEPLTTVYKKQTSQNGCSSTSNPSSSPGSSPTTSGSTATLLIHSQRLGNSTAPASHCVAVPATATATSSASSSNSSSGKSTSAAHHLHHHHMHHHHHHHHHHVVIAAKNAAAVAATNNLSLDQGIIC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: .*** . .: :. ::*::* : . :.*****.**:.* *.**..:*** **:***.*.. ** ****** *... .::**: *:*. :: *:** *:***: : : * ::* :. : ::::*:.: :**:..*.***********:. ..:*: ***:** : .. ::**: ***:*:***:*:*:*:: **:*.:*:::*:**: *** *: :***:***** : :.:: *..** :* ***: * :*:.* .* **.* **:: * ::*:. : ..: *: : .* : .*. ** .. **** ** ::::. * *: ..*: : ", "identical_positions": 132, "similar_positions": 133, "identity": "19.53%" }, { "cls_id": "homologset.agr.MGI:2138198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C3M9-1", "uniprot_id": "CB080_MOUSE", "id": "Q8C3M9-1", "name": "Uncharacterized protein C2orf80 homolog", "aln": "MERRLVKQEVKRLLGEYIGIRLRENEFDPKGRGQLTFLDDMVNQVTLAHYDLAISVASQWLDCSENLTWLQWEKVRAPLHVRPAYPNRKEREAMILSSYAGVLMNSIPIEEVLKIYGANSSASPDSTKVAQALLPRRSLHPFAMLTAPRAAECNRRQSVKLRRGATNKNTTSSSTKKATGQNGDPVGKGTHTPATNISPTPVLSSAQPFHSSTVMWRNLESAQRQMGLEGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0P641-1", "uniprot_id": "CB080_HUMAN", "id": "Q0P641-1", "name": "Uncharacterized protein C2orf80", "aln": "MERRLIKKEMKKLLGDYIGIRLRENEFDPKGRRQLTFLDDMA------HYDLAISVALQWLDPSEDLTWLEWEELKIPLHGRPIYPNRREREAMILSSYAGILMNSIPIEEVFKIYGADSSADSGTIKVPRVSSLCLSLHPFAMLTAPKAAAYARKQSVKSRKVTTNKNATSISAKEAN--------------ATEWKSSQRFSDTQPKHKVT------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*:*:*:***:**************** ********. ********* **** **:****:**::: *** ** ****:************:**********:*****:***...: **.:. ***********:** *:**** *: :****:** *:*:*. **: ..: :*.:** *. * ", "identical_positions": 132, "similar_positions": 38, "identity": "57.14%" }, { "cls_id": "homologset.agr.MGI:2138209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIM3-1", "uniprot_id": "D2HDH_MOUSE", "id": "Q8CIM3-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "MVLPLVSRWSARVLWASPGWRRTYTQRACVGLKRLGCPRGVYSPLAHRAYSVVAGGPEVTLTPERYPVQRLPFSTVSEEDLAAFECIIPGRVIT---DPEQLQTCNVDWLKTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVPVFDEVILSTALMNQVISFHDVSGILVCQAGCVLEELSRYVQERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTILNCLTSLRKDNTGYDLKQMFIGSEGTLGVITAVSIVCPPRPKAVNVAFLGCPGFAEVLQTFRTCRGMLGEILSAFEFMDTECMQLVGQHLQ-LTNPVQ-ESPFYVLVETSGSSAGHDAEKLTNVLEQVLNSGLVTDGTMATDQRKVQMLWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRL------GPRAKHVV---GYGHLGDGNLHLNVTAEAFSRELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKDVLGYSKPPVAVTLMQQLKAMLDPEGILNPYKTLPAQA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84850-1", "uniprot_id": "D2HDH_RAT", "id": "P84850-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "MVLHLVPRWSASLFRASPRWKKTYSQRASAQLKWLGCPRSVYSPLACRAYSKVSGSPEVMLTPERYPVQRLPFSTVSEEDLAAFECIIPGRVIT---DPEQLQTCNVDWLRTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVPVFDEVILSTALMNQVISFHDVSGILVCQAGCVLEELSRYVQERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTILNCLTSLRKDNTGYDLKQMFIGSEGTLGVITAVSIVCPPRPKAVNVAFLGCPGFTEVLQTFRTCKGQLGEILSAFEFMDAECMQLVGQHLH-LTNPVQ-ESPFYVLVETSGSSAGHDAEKLTNVLEQVLNSGLVIDGTMATDQRKVQMLWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRL------GPRAKHVV---GYGHLGDGNLHLNVTAEAFSQELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKNVLGYSKPPVAVKLMQQLKAMLDPKGILNPYKTLPARA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N465-1", "uniprot_id": "D2HDH_HUMAN", "id": "Q8N465-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "MLPRRPLAWPAWLLRGAPGAAGSWGR--------------PVGPLARRGCCSAPGTPEVPLTRERYPVRRLPFSTVSKQDLAAFERIVPGGVVT---DPEALQAPNVDWLRTLRGCSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNRVLSFHSVSGILVCQAGCVLEELSRYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITTVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRHLH-LASPVQ-ESPFYVLIETSGSNAGHDAEKLGHFLEHALGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARL------GPHAKHVV---GYGHLGDGNLHLNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQLKALLDPKGILNPYKTLPSQA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L258-1", "uniprot_id": "D2HDH_DANRE", "id": "A1L258-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "--MGLFQKCSRLSLRSSYMWSVCPQYSIAVTARETPDRALIVHWTQHRDVHNSRRLGANPANPSAAPP-RLPFSRVTQEDLSFFRALLPGRTIT---DPDLLKSSNVDWLKTVQGSSDVLLRPKTTEGVSQILRYCNERNLAVCPQGGNTGLVGGSVPVFDEIILSTSLMNQVFAFDNISGILTCQAGCVLENLSHYLEERDFIMPLDLGAKGSCHIGGNVSTNAGGLRLLRYGSLRGTVLGLEVVLADGHVLNCLATLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPRKPKAVNVAFLGCSSFQQLLETFQCCRGMLGEILSAFEFLDASCMNLLEKHLK-LTNPIT-ECPFYIVIETAGSNATHDEEKLHQFLEEVMTSSLVTDGTVATEATKIKALWSLRERVTEALTHEGYTYKYDISLPVEKIYDLVQDMRRHL------GGMAKNVV---GYGHVGDGNLHLNITSPSKDFDLLAAIEPYVYEWTSQWKGSISAEHGLGLKKRNYIYYSKPSEAVALMGSIKAMLDPKGILNPYKTLPDNIN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39976-1", "uniprot_id": "DLD3_YEAST", "id": "P39976-1", "name": "D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3", "aln": "-----------------------------------------MTAAHPVAQLTAEAYPKVKRNPN--------FKVLDSEDLAYFRSILSNDEILNSQAPEELASFNQDWMKKYRGQSNLILLPNSTDKVSKIMKYCNDKKLAVVPQGGNTDLVGASVPVFDEIVLSLRNMNKVRDFDPVSGTFKCDAGVVMRDAHQFLHDHDHIFPLDLPSRNNCQVGGVVSTNAGGLNFLRYGSLHGNVLGLEVVLPNGEIISNINALRKDNTGYDLKQLFIGAEGTIGVVTGVSIVAAAKPKALNAVFFGIENFDTVQKLFVKAKSELSEILSAFEFMDRGSIECTIEYLKDLPFPLENQHNFYVLIETSGSNKRHDDEKLTAFLKDTTDSKLISEGMMAKDKADFDRLWTWRKSVPTACNSYGGMYKYDMSLQLKDLYSVSAAVTERLNAAGLIGDAPKPVVKSCGYGHVGDGNIHLNIAVREFTKQIEDLLEPFVYEYIASKKGSISAEHGIGFHKKGKLHYTRSDIEIRFMKDIKNHYDPNGILNPYKYI-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P46681-1", "uniprot_id": "DLD2_YEAST", "id": "P46681-1", "name": "D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2", "aln": "MLRNILVRSTGSNFKFAGRYMKSSALLG-------YYRRVNYYSTKIQTRLTSENYPDVHRDPR--------FKKLTSDDLNYFKSILSEQEILRASESEDLSFYNEDWMRKYKGQSKLVLRPKSVEKVSLILNYCNDEKIAVVPQGGNTGLVGGSVPIFDELILSLANLNKIRDFDPVSGILKCDAGVILENANNYVMEQNYMFPLDLGAKGSCHVGGVVATNAGGLRLLRYGSLHGSVLGLEVVMPNGQIVNSMHSMRKDNTGYDLKQLFIGSEGTIGIITGVSILTVPKPKAFNVSYLSVESFEDVQKVFVRARQELSEILSAFEFMDAKSQVLAKSQLKDAAFPLEDEHPFYILIETSGSNKDHDDSKLETFLENVMEEGIVTDGVVAQDETELQNLWKWREMIPEASQANGGVYKYDVSLPLKDLYSLVEATNARLSEAELVGDSPKPVVGAIGYGHVGDGNLHLNVAVREYNKNIEKTLEPFVYEFVSSKHGSVSAEHGLGFQKKNYIGYSKSPEEVKMMKDLKVHYDPNGILNPYKYI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : .:** *. ::. : .: * * **::. :* *.::* *.: : ** *:.:* ..::** ******.:**.***:***::** :*:: *. :** : *:** ::.: .:: :::.::**** ::..*::** *:******.:******:*.*******:.:* ::. : ::***********:***:***:*::* ***: :*:*.*. ::. .* : : * .: *.********:* . *: . *: : **:::**:**. ** .** .*:.. . :: :* :* : ... ** *: :. * * :***:** :: :*.: :* * .* ** ****:****:***:: .: :**.** : : :**:*****:*::*:. : *::. : :* .:* **:******* : ", "identical_positions": 174, "similar_positions": 157, "identity": "31.64%" }, { "cls_id": "homologset.agr.MGI:2138232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9Z7-1", "uniprot_id": "D3Z9Z7_RAT", "id": "D3Z9Z7-1", "name": "", "aln": "MAAR-RATVACALLLLSSALLRRGCPARFAAESESDEDGEETVAFPESPLQKPTVFVVVLARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEILREWLKNVQRLYHYVEWRPMD-EPESYPDEIGPKHWPSSRFAHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNLMIAENKTILAPMLESRGLYSNFWCGITPQGFYKRTPDYLQIREWKRTGCFPVPMVHSTFLIDLRKEASDKLSFYP-----------PHQDYTWTFDDIIVFAFSSRQAGIQMYLCNKEHYGYLPIPLKPHQTLQEDIENLIHVQIEAMIDRPPMEPSQ--FVSVVPKY-PDKMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLKAWNIEMLPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRFEHQFKRKLMKLMDDIDKARLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSYWTLGYVISLEGAQKLVGADPFGKMLPVDEFLPIMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETSTIWDNETVATDWDRTHSWKSRKQGPIHSNAKNTEALPPPTSLDTVPSRDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVG7-1", "uniprot_id": "GT252_MOUSE", "id": "Q6NVG7-1", "name": "Procollagen galactosyltransferase 2", "aln": "MAAR-LATVACALFLLSSALLRLGCRARFAAEPDSDEDGEETVAFPESPPQKPTVFVVVLARNAAHTLPYFLGCLERLDYPKSRMAIWAATDHNVDNTTEILREWLKSVQRLYHYVEWRPMN-EPESYPDEIGPKHWPNSRFSHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNLMIVENKTIVAPMLESRGLYSNFWCGITPQGFYKRTPDYLQIREWKRMGCFPVPMVHSTFLIDLRKEASDKLAFYP-----------PHQDYTWTFDDIIVFAFSSRQAGIQMYLCNKEHYGYLPIPLKPHQTLQEDVENLIHVQIEAMIDHPPMEPSQ--FVSVVPKY-PDKMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLKAWNIEMLPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRFEHQFKRKLMKLMEDIDKAQLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSYWTLGYAISLEGAQKLVGADPFGKMLPVDEFLPIMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETSTIWDNETVATDWDRTHSWKSRKQGHIRSTAKNTEALPPPTSLDTVPSRDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYK4-1", "uniprot_id": "GT252_HUMAN", "id": "Q8IYK4-1", "name": "Procollagen galactosyltransferase 2", "aln": "MAARPAATLAWSLLLLSSALLREGCRARFVAERDSEDDGEEPVVFPESPLQSPTVLVAVLARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEIFREWLKNVQRLYHYVEWRPMD-EPESYPDEIGPKHWPTSRFAHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNLLIAENKTIVAPMLESRGLYSNFWCGITPKGFYKRTPDYVQIREWKRTGCFPVPMVHSTFLIDLRKEASDKLTFYP-----------PHQDYTWTFDDIIVFAFSSRQAGIQMYLCNREHYGYLPIPLKPHQTLQEDIENLIHVQIEAMIDRPPMEPSQ--YVSVVPKY-PDKMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLKALNIEMLPGYRDPYSSRPLTRGEIGCFLSHYSVWKEVIDRELEKTLVIEDDVRFEHQFKKKLMKLMDNIDQAQLDWELIYIGRKRMQVKEPEKAVPNVANLVEADYSYWTLGYVISLEGAQKLVGANPFGKMLPVDEFLPVMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETSTIWDNETVATDWDRTHAWKSRKQSRIYSNAKNTEALPPPTSLDTVPSRDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9C3Q0-1", "uniprot_id": "A9C3Q0_DANRE", "id": "A9C3Q0-1", "name": "", "aln": "-----MPAEGFVFAAVICAVMAQNCSGELMAHVQDPN------PVPESSLLKPKVMIAILARNSAHSLPYYLDCIDRLDYPKDRIAIWAATDHNVDNSTAMLREWLKNRQSRYHYVEWRPME-EPRSYTDEWGPKHWSSSRVSHVMKLRQAALKAARARWADYILYVDSDNLLTNPRVLNLLMAENLTLVAPMLDSRSLYSNFWCGITPQGYYKRTPDYQPIREWKRLGCFSVPMVHSTFLLDLRRSATLDMAFYP-----------PHPDYSWAFDDIMVFAFSAREAGVQMYVCNREHYGFLPVPLKAQQSVEDEEESFTHTITEAMIDHN-IKPSE--FLFTPSKP-QDKMSFDEIFLINLKRRFDRRERMLNTMAVLGLEATLVDAVDGKTLNTSQLQALGIEMMPGYKDPYSGRVLTRGEIGCFLSHHFTWKQVLERGLRHVLVLEDDVRFEPRFKRRLQTIMKDVEKTQLNWDLIYVGRKRMQVAQPEVSVEGVNNLVEADYSYWTLGYALSQQGAKKLLAAQPLGKMLPVDEFLPVMFNKHPNSAYMSHFDPRDLRAFSVEPLLLYPTHYTGEPGYFSDTETSTIWDDESVNTDWDRQYAQKTAQQAQIRSVAQNSVTGDTPAPASRAS-RDEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YUW4-1", "uniprot_id": "A0A8M6YUW4_DANRE", "id": "A0A8M6YUW4-1", "name": "", "aln": "-----MMDPRASGKLLLGLVMLESWIGFIYTHTDLEP------VLHETSLLNPKVAIAILARNSEHSLPYFLGCIERLDYPKDRISIWAATDHNTDNTTGMLREWIAGVEDLYHSVQLHTMEQEKSSYVDELGPKHWPETRFTHVMKLRQAALKSARAQWADYVLFTDSDNLLTNTQVLNQLISENRTLVAPMLDSRTLYSNFWCGMTSQGYYKRTPHYVPIRTWKRTGCHPVPMIHSTMLIDLRRRASELLAFYP-----------VHHHYLWALDDIMAFAFSARQTGVQMFICNREHYGYLPQPLQMKQTLEEEVESFSHTVTEALVDFK-METSQ--YLHIVSKP-KDTMAFNQVYLINLKRREDRRDRMLRSLEVLGIDVTLTDAVDGKAMNSTQLRTLGIEMLPGFKDPYSDRVLTKGEIGCFLSHYNIWKKVVELQQQQVLVLEDDVRFETNFKSRLNTIMEDVKRSGLQWDLIYVGRKRLQIKHPERWVEGVKNLVSPDYSYWTLGYALSLQGAKILLEAQPLSKMLPVDEFLPVMFNKHPKKEYMSHFQLRNLKAFSVQPLLLFPTHYTGEAGYFSDTETSSIWDDETVSTDWDRN---------RIR-------GGKTTTSVSESSPKDEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPK4-1", "uniprot_id": "GLT25_DROME", "id": "Q8IPK4-1", "name": "Glycosyltransferase 25 family member", "aln": "------MNKQVIFGLLLACILVC------ISGQDEED-------YQES----PTVLIALLVRNKAHILPMFLSYLEQQDYPKERIAIWLRCDHSNDDSIELLRQWLDNSGDLYHSVSYEFKP-EEQSFVNGTSPYEWPASRFKHLIALKEEAFQYGRDIWADYVFFLDADVLLTSKDSLKVLTRLQLPIVAPMLISESLYSNFWCGMTEDYYYRRTDEYKEIYHVKKQGSFPVPMVHTAVLVNMNHRAVRNLTFDRNKLVELQKSRQQEPLYDGPADDIIVFAISANSSGIPLHICNDITFGYILQPLEPGDTLDHDVQQLVNLKSIMVNELGAVPPLLDYYKHLEKKPEKSKLSLDRIFMINLKRRPERREKMERLFDEIGIEAEHFPAVDGKELSTERLLEMGVRFLPGYEDPYHHRAMTMGEIGCFLSHYNIWVMMVRKQLKEVLILEDDIRFEPYFRQNAVRILNQARN-AAQYDLIYFGRKRLKE-ESEPAVENADNLVHAGYSYWTLGYVISLQGALKLLAAKPLDKLIPVDEFLPLMFDRHPNKTWTEAFPKRNLVAFSASPLLLYPIYYTGESGYISDTEDS---QQISVETSEEGEARLKSDREQVFDHEQEFKLNPELKLGESLSKSHQEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : *: *.* :.:*.** * ** :*. ::: ****.*::** **. *:: ::*:*: . ** *. . * *: : .* .*. :*. *:: *:: *:: .* *:**::: * * :**. *: : : .::**** *. ********:* . :*:** .* * *: *...***:*::.*:::.: * ::* . * . ***:.**:*:..:*: :.:** :*:: **: ::::.: :.: : : : : . : * ..:.::.:::****** :**::* . : ::. ***** :.: :* .:.::**:.*** * :* *********. * :: ...*::***:*** *: . ::.: . :::***.****:: ..* * .. *** ..********.:* :** *: *.*:.*::*******:*:::** : . : *:* ***..***::* :***:.**:**** * :: :* *. : : . ::**", "identical_positions": 184, "similar_positions": 200, "identity": "28.71%" }, { "cls_id": "homologset.agr.MGI:2138243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AFY0-1", "uniprot_id": "A0A8I6AFY0_RAT", "id": "A0A8I6AFY0-1", "name": "", "aln": "MVNEYKRIVLLTGLMDITDHEFKMVKALLRKELKLNKMQDKYDRVKIADLMEDKFPKDAGLDQLIKLYKEIPGLRNIADTLKKAKAKAKMKQIKKRKTAEKRQRREEPSTSQPMSTINEDVEPETGR-------------------------------------RST----QVIKARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BV49-1", "uniprot_id": "IFIX_MOUSE", "id": "Q8BV49-1", "name": "Pyrin and HIN domain-containing protein 1", "aln": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNRMQDQYDRVKIADLMEDKFPKDAGVDQLIKLYKQIPGLGDIANKLKNEKAKAKRTRTGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPKTPKRPSSSILDPPVSSGTASSSAQALGVPLATIAKRQRLKNVPKEPSEENGHQQGSKKVMVLKVTEPFSYDVTEEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKKRGIFVNGVFTVCKKEEKWNYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLICFKLIPDEEKAQLRSTTHSNMQVIKAKN", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************.*.**:*:***:** ******:***:*******************:********:**** :**:.**: ***** .: ***** ****:*********** ***.***:** **: .:*:: * ", "identical_positions": 105, "similar_positions": 23, "identity": "25.0%" }, { "cls_id": "homologset.agr.MGI:2138261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VZ6-1", "uniprot_id": "SMAP1_MOUSE", "id": "Q91VZ6-1", "name": "Stromal membrane-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTPEQIQCMQDMGN-TKARLLYEANLPENFRRP--QTDQAVEFFIRDKYEKKKYYDKNAIAITN---------------------------KEKEKKKDEKKREKEPEKPAKPLTTEKLPKKEEQQLEPKKSTSPKNAAEPTIDLLGLDGPAEAPVTNGNP-ATAPALSDDLDIFGPMISNPLP----AAVMPPAQGTASVPAPATLSTVT-----------------------SGDLDLFTEQT--TKSEEVAKKQLSKDSILSLYGTG--AQQSTPG--VFMGPTNIPFTSQAPTAFQGFPSMGVPVP------AAPGLIGNMMGQNTGMMVGMPMHNGFMG--------------------------NAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWNLSQMNQQMAAMNLSSANASAGFGQPPSTTAGWSGSSSGQTLSTQLWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L9X6-1", "uniprot_id": "A0ABK0L9X6_RAT", "id": "A0ABK0L9X6-1", "name": "", "aln": "MRSAQSSVLPEAAALPAPPLAGSGGACGGPGEEAGHVGAASAAAAPPPVPAAAATATAAAAAAASWAESARGPSGARFPRPPGLISAVRPLARVPARRPAADMATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTPEQIQCMQDMGN-TKARLLYEANLPENFRRP--QTDQAVEFFIRDKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLPAAVDKNKIEKEKEKKKEEKKREKEPEKPAKALTTEKLQKKEDQQPEPKKSTSPKNVAEPTVDLLGLDGPAEAPVTNGNT-TAAPPLSDDLDIFGPMISNPLP----AAVMPQAQGTASIPAAAALSTIT-----------------------SGDLDLFTEQT--TKSEEGAKKQLSKDSILSLYGTG--AQQSTPG--VFMGPTNIPFTSQAPTAFQGFPSMGVPVP------AAPGLMGNMMGQNTGMMVGMPMHNGFMG--------------------------NAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAAMNLSSANSSAGFGQPPSTTAGWSGSSSGQTLSTQLWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYB5-1", "uniprot_id": "SMAP1_HUMAN", "id": "Q8IYB5-1", "name": "Stromal membrane-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGN-TKARLLYEANLPENFRRP--QTDQAVEFFIRDKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKEPEKPAKPLTAEKLQKK-DQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGN--TTVPPLNDDLDIFGPMISNPLP----ATVMPPAQGTPSAPAAATLSTVT-----------------------SGDLDLFTEQT--TKSEEVAKKQLSKDSILSLYGTGTIQQQSTPG--VFMGPTNIPFTSQAPAAFQGFPSMGVPVP------AAPGLIGNVMGQSPSMMVGMPMPNGFMG--------------------------NAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9Y2-1", "uniprot_id": "A0A8M9Q9Y2_DANRE", "id": "A0A8M9Q9Y2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTTRSEREKAQKLNEQHQAILSKMLREDDNKYCADCEAKG-PRWASWNLGVFICIRCAGIHRNLGVHISRVKSVNLDQWTPEQIQSVQSMGN-TKARQLYEAHLPENFRRP--QTDQAVEFFIRDKYERKKYYDKNSVNGAIKSSD--AALPSVSSPSSQ-AAEKSKLEKEREKKKEEKKREKDTDKENKPAVLEK--KREDNQIDSR--ISPKKSAEPAIDLLGLDAPTVGSASSGAGTSSAAPISDDLDIFGPMVSNPLPSNSNSSQVSSSKAAGSAQASSAGGAVAGATGTGSAAPA------------QGDLDLFSETSGNSKAEDSAKKPLSKDSILSLYGSSTVPQQPAQATAMFMGPSQMQFPAQPQGNFQAFPGMGGAMPPTTMMGAVMGQGGAMMGQNTGMMVGMTMPNGFMG--------------------------NAQPGVMGLAPGMMGPQG-----MVPPQNMYAMQPGQQGQWNMAQINQQMSGMNLNGSGAPMAFGQPGAPMGGWVAPPSGQTLSTQLWK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40529-1", "uniprot_id": "AGE2_YEAST", "id": "P40529-1", "name": "ADP-ribosylation factor GTPase-activating protein effector protein 2", "aln": "------------------------------------------------------------------------------------------------------MSTSVP----------VKKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWKEEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTSSLQNFIKNKYEYKKWIG-----------------------------------DLSSIEGLNDSTEPVLHKPSANHSLPASNARLDQSSNSLQKTQTQPP---------------------------------SHLLSTSRSNTSLLNLQVSSLSKTTSNTSVTSSATSIGAANTKTGN--------------------------RVGEFGQRND-----LKKSILSLYSKPSAQTQSQNSFFTSTTPQP------------------------------CNTPSPFVNTGITATNNNSMNSNS-----------------------------------------------------------------------------------------------SSNISLDDNELFK-----NVWS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1Z7K6-1", "uniprot_id": "A1Z7K6_DROME", "id": "A1Z7K6-1", "name": "Arf-GAP domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------MSSSNAGQRTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKG-PRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTWTPEQVISLQQMGN-SRARAVYEAQLPDGFRRP--QTDTALENFIRAKYEHKKYLAREWVPPSPPKVD----------------WAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLPAPLPKPKPNQVGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSPTKPIVATNASQDLQNESFTSFLSAESIAGQPDKPIGSNGDAANLMGSKPNSLAQEEQDFFNQGSLGAGGNEKDQSGKMSKDSILALYGSAPATHNPQMNFGGFTGMAPGGYMHQQQQQQIPHQFMTPPNSVSMYNSPVMAAPNAFSNAAISSATAMSMGGSHGFTGAQFPSTGGSPYAAAGQAAATNLMQTNQSILSGMPLFGAVPQQQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQGAGGFAATGPTTSSVPSNLNQQFGNLNIGNVWQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : *: :**: .*.:*.**.*: ******.:*:*:**:******.**.***:****:** *. *:: : .: * :*. *** *.: ::: ::: **: *** **: . : :.. : : . . . . .::. .. : . * :. : . .. *.***:**.. :. . . . .* .. : ::*.", "identical_positions": 60, "similar_positions": 80, "identity": "9.39%" }, { "cls_id": "homologset.agr.MGI:2138271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1H222-1", "uniprot_id": "GORAB_RAT", "id": "B1H222-1", "name": "RAB6-interacting golgin", "aln": "MAQGWAGFSEEELRRLKQNKD-----------PFEPQR-------RLPVK--KTRQQLQREKALLE----QSQKLGLQDGSASLLPEQL------------------LSTPKQRASSQKPPPSSPAVPSPLTLTSSTGDGELHGGESQLQEPGLENSHHGSRS-AEIQTPKPDCKVEKKKMELQEKSR---WEVLQQEQRLMEEKNKRKKALLAQAIAERSRRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASLEYSYARKRFDRAEAEYVTAKLDLQRKTETKEQLTEHLCTIIQQNELRKAQKLEELMRQLDVQADDEALELELEVEQLLREQEAEAARQMAPVERLSQPDGEGVSSELTEENKEPQKPATSPETDKSGKCCSSSPRR-LDCPDPGAQNFPAAVAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRM2-1", "uniprot_id": "GORAB_MOUSE", "id": "Q8BRM2-1", "name": "RAB6-interacting golgin", "aln": "MAQDWAGFSEEELRRLKQNKD-----------PFEPQR-------RIPVK--KTRQQLQREKALLE----QSQKLGLQDGSASLLPEQL------------------LSAPKQRANSQKPRSPSPVAPSPLTPTSSSGDGKLPGVGSQPQEPGLENSHHGHKS-AEVRAPKPDCKVEKKKMELQEKSR---WEVLQQEQRLMEEKNKRKKALLAQAIAERSKKTQAETIKLKRIQKELQALDDMVSADIGILRNRIDQASLEYSYARKRFDRAEAEYITAKLDLQRKTETKEQLTEHLCTIIQQNELRKAKKLEELMQQLDVQADEEALQLEVEVEQLLREQEAEAAKQMASVERLCPPDGESVSSELAEENNEPQKQAPSPETDKPGKCCSSSPHR-LDCPDPGAKNFSAAVAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T7V8-1", "uniprot_id": "GORAB_HUMAN", "id": "Q5T7V8-1", "name": "RAB6-interacting golgin", "aln": "MAQGWAGFSEEELRRLKQTKD-----------PFEPQR-------RLPAK--KSRQQLQREKALVE----QSQKLGLQDGSTSLLPEQL------------------LSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNN-VEILPPKPDCKLEKKKVELQEKSR---WEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASLDYSYARKRFDRAEAEYIAAKLDIQRKTEIKEQLTEHLCTIIQQNELRKAKKLEELMQQLDVEADEETLELEVEVERLLHEQEVESRRPVVRLERPFQPAEESVTLEFAKENRKCQEQAVSPKVDDQCGNSSSIPFLSPNCPNQEGNDISAALAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T320-1", "uniprot_id": "GORAB_DANRE", "id": "Q7T320-1", "name": "RAB6-interacting golgin", "aln": "-MAAWAGFSEEELRKLQHNGE-----------VANQAVSVTLGRGRKPAQTNRSRQQLQRERALQL----AAK---QKEISQSLLPDQQ------------------LTRPPE------PPASSHPAPPAETPDEQS---VPVKHEAEPVKP------DPASP-VQSIPPADFKELDKQEVELREKNR---LQQLQWEQRIMEEKNKKRKALLTKTIAEKSKQTQAEAIKLKKIQRELQVLDDSVSSDIGVLRKLIEQSSMDYSLAWKRFEKAEAEYVAAKMDLHRKTEVKEQLTEHLCAIIQQNELRKARKLEELMLQLELNAEEVPSPDQTQLQDKQKEPVTENG-PAAELERCTEANGSSMSKDSSITETKISQ----------------------DNQESEAADVSADGLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQQ4-1", "uniprot_id": "GORAB_DROME", "id": "Q8IQQ4-1", "name": "RAB6-interacting golgin", "aln": "MTEKFNGFSHDEILKITGVKEGGVGKRPASLEAAKPALRIQPGIRRMPDKIFRQADQLRKQQQQQPQQPIQKPDVAKKTKSGTATPTEKPPTPTPAAEDDVANGSLNLDRPLSDSLIEALYHGNATARDKKTPATYADAETTSTDDSSILKISGGDSQTTSSTDDGSILPSTQDTSPRERLNTDSPFKGISLKDFEQHRRMIEEQNKQKKQMLYQAIEQHTQKTAAESRKIEEIRHELSKLESDLAVDVALLRKQIDNACIHFANVEKQYVKIEAQFLRAKIELHNASEKKELLTEHLCTVIAHNEDRKAQKLTELMQKVGLSPTDDCQPIDLTQQSP-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***.:*: :: : : * * : : :**:::: : * : * : * * . . * :. : * ::.:: . : : :: .:*::**:**::* :* ::* :::::* **: *::.*::**. *:. :: *:.:**: *:::.:.:: . *:: : **::: **::::. :* ** ******::* :** ***:** *** :: :.. : : : ", "identical_positions": 59, "similar_positions": 96, "identity": "14.22%" }, { "cls_id": "homologset.agr.MGI:2138281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08984-1", "uniprot_id": "LBR_RAT", "id": "O08984-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPGRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKESDIKPLKSFKQR-KSGSTSSSPSRRRS-SRSRSRSRSR--SPGRAPKG----------------------------------SRRSVSASYQADAKEK---EMRREILQVKLTPLVLKPFANSVSVYNGEPEHMEKSATPPKNKQERVILSTEDSYIATQYSLRPRREEVKPKHRVRG-TNLVTRGPVPLGTFQVTTPQRRDLEFGGVPGALLIMLGLPACVFLLLLQCA---------QKDPGLLQFPPPLPALRELWEARVCGVYLLWFFLQALFSLLPVGKVVEGTPLVDGRRLKYRLNGLYA----FILTSAAVGTAVFWDIELYYLYTHFLQFALAAIVFSVVLSVYLYARSLK--------VPRDE--LSP-ASSGNAVYDFFIGRELNPRIGAFDLKFFCELRPGLIGWVVINLVMLLAEMKVQ-------------------ERSAPSLAMTLVNSFQLLYVVDALWFEEALLTTMDIIHDGFGFMLAFGDLVWVPFTYSLQAFYLVNHPQDLSWPLTSVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIPTSTWKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILP-YFYVIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U9G9-1", "uniprot_id": "LBR_MOUSE", "id": "Q3U9G9-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQR-KSGSISSSPSRRRG-SRSRSRSRSRSRSPGRAPKG----------------------------------SRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCR---------QKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYA----FILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLR--------APREE--LSP-ASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQ-------------------ERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLP-YFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14739-1", "uniprot_id": "LBR_HUMAN", "id": "Q14739-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPSRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKENDIKPLTSFRQR-KGGSTSSSPSRRRG-SRSRSRSRSP----GRPPKS----------------------------------ARRSASASHQADIKEA------RREVEVKLTPLILKPFGNSISRYNGEPEHIERNDAPHKNTQEKFSLSQESSYIATQYSLRPRREEVKLKEIDSKEEKYVAK-ELAVRTFEVTPIRAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCK---------QKDPSLLNFPPPLPALYELWETRVFGVYLLWFLIQVLFYLLPIGKVVEGTPLIDGRRLKYRLNGFYA----FILTSAVIGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLK--------APRND--LSP-ASSGNAVYDFFIGRELNPRIGTFDLKYFCELRPGLIGWVVINLVMLLAEMKIQ-------------------DRAVPSLAMILVNSFQLLYVVDALWNEEALLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMASLIIVLKLCGYVIFRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILP-YFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRIFPYIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PP65-1", "uniprot_id": "A0A8M9PP65_DANRE", "id": "A0A8M9PP65-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPPARFQIGDTVMGRWPGSNLYYEVKVMSFDNKTRLYTVIYKDGTELELKESDITSVVIFQTAGRSRSRSRSPGRSPGRSSARSPGRPR-RSRSRSPAR----------------------------------TPRRASSRSTEVRKEK-----LKEVLEVRLTPVAMKHENNSSNSKSEKKEENNTAKAAPVVTEEKTETESEN-QTGGRYNLRRRKDQGDGKAVELE---KAVESEPLLQTKAPAAVKTADLEFGGRVGVLFLMFLLPVAVLVLLILCG---------QKDASLQSFPLELPALQSVWDCQVFGIVLLWLLFQAVLSLLPVGKLVEGMPLKNGKTLKYRINGFYA----LLLTAVAAGVAVYQEVDLSYIHAHFLQFYTSALLIATLLSIYLFIRSRW--------ASKDE--LAPGGNSGYIIYDFFMGRELNPRIKSFDIKFFCEMRPGLMGWVLINFAMLLAEMKQQ-------------------NLENPSPAMLLVNIFQLLWVIDGLWHEEKLLTMMDIMYDGFGFMLTFGDLAFVPFTFTCQAYYLVNHPNELSVFWIITLIAMNGVGYYIFRKANSQKFAFRKNPSDPAVSHLKTIPTATGKSLIVSGLWGFVRHPNYLGDIIMALAWSLPCGFNNLVP-YFYLIYLVTLLVHRNARDERQCRKKYGSAWEEYCKAVPYRIFPRVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32462-1", "uniprot_id": "ERG24_YEAST", "id": "P32462-1", "name": "Delta(14)-sterol reductase ERG24", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSALNPRTTEFEFGGLIGALGISIGLPVFTIILNQMIRPDYFIKGFFQNFDIVELWNGIKPLRYYLGNRELWTVYCLWYGILAVLDVILPGRVMKGVQLRDGSKLSYKINGIAMSTTLVLVLAIRWKLTDGQLPELQYLYENHVSLCIISILFSFFLATYCYVASFIPLIFKKNGNGKREKILALGGNSGNIIYDWFIGRELNPRLGPLDIKMFSELRPGMLLWLLINLSCLHHHYLKT-------------------GKIN--DALVLVNFLQGFYIFDGVLNEEGVLTMMDITTDGFGFMLAFGDLSLVPFTYSLQARYLSVSPVELGWVKVVGILAIMFLGFHIFHSANKQKSEFRQG----KLENLKSIQTKRGTKLLCDGWWAKSQHINYFGDWLISLSWCLATWFQTPLT-YYYSLYFATLLLHRQQRDEHKCRLKYGENWEEYERKVPYKIIPYVY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8MLV1-1", "uniprot_id": "LBR_DROME", "id": "Q8MLV1-1", "name": "Lamin-B receptor", "aln": "MQHSPSTTTDHIHFAARFFDRNSYTMDRRLRRPRRTEDVSSGPLLAQSKQPSLLPVTRRTGSVTAAGATATATATAGPATRTRASPSRNKVVAPPSPDLGPRTRRSSRPRSSVGPLTGSGSGSSLPIKAAIKARTPIPEVSEVSSPIRLSTSNLPMTLTTNTSSGAPNKAFNTSSVNSGNSFSRTTTSSTTTTTERIEIRAEGDGEVDTDSIRKRITERLRRSVSKTISNLAGTPVTNTEEGSRYSRSVSRSVYDDEKSSKRSYSTGEEDIDEEDELEEDQFRSFNVTRKSATPAEISCRQLKAP-REFGGWLGAFLFLLLLPTAVYYLTWSCTARN---ACQFKHLNLGILLDVNYLTRQVFQPRVVGAFAAYQVVVFLLVALLPGRRVHLT------RETYKFNCLAVS---LTLLIASGVAEYLKYPVVTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDT-----AKYNVLRQTLTNDYGRTGSFVVDFALGRQLNPKWLGRVDWKQFQYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGYLYQAKYYWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLLLRYAATPYLLTAVTKYFYEQRVPISCWYAPLAVAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPRVY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **** *.. : : **. * : : : : .: : . :: : *: . *::* : . : . :: :.: : . . . : : : : . :* : *: :**:***: : * .:: :: : * : :::.*.: *. : : ::: :*:* :* : : : : : .: * : : : * :* . . ::::* * . *: .* *. :: **:** : *: . . :. . : **:** * : : : :* *:.* * *:* :*", "identical_positions": 50, "similar_positions": 109, "identity": "6.59%" }, { "cls_id": "homologset.agr.MGI:2138283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54702-1", "uniprot_id": "CHSTA_RAT", "id": "O54702-1", "name": "Carbohydrate sulfotransferase 10", "aln": "MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDGYSAKQEFVFLTAMPEAEKLRGEKHFSEVMKPTGKMLSESHP------DQPPVYLERLELIRNACKEEALRNLSHTEVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSKIGIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRK---NRTETRGIQFEDFVRYLGDPN-RRWLDLQFGDHIIHWVTYVKLCAPCEIKYSVIGHHETLEADAPYILKEAGIDHLVSYPTIPPGITMYNRTKVEQYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGK7-1", "uniprot_id": "CHSTA_MOUSE", "id": "Q6PGK7-1", "name": "Carbohydrate sulfotransferase 10", "aln": "MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDGYSAKQEFVFLTTMPEAEKLRGEKHFPEVPKPTGKMLSDSRP------DQPPVYLERLELIRNTCKEEALRNLSHTEVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSKIGIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRK---NRTETRGIQFEDFVRYLGDPN-RRWLDLQFGDHIIHWVTYVELCAPCEIKYSVVGHHETLEADAPYILKEAGIDHLVSYPTIPPGITMYNRTKVEQYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43529-1", "uniprot_id": "CHSTA_HUMAN", "id": "O43529-1", "name": "Carbohydrate sulfotransferase 10", "aln": "MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDVYSAKQEFLFLTTMPEVRKLPEEKHIPEELKPTGKELPDSQL------VQPLVYMERLELIRNVCRDDALKNLSHTPVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSDAEIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRR---NRTETRGIQFEDFVRYLGDPN-HRWLDLQFGDHIIHWVTYVELCAPCEIMYSVIGHHETLEDDAPYILKEAGIDHLVSYPTIPPGITVYNRTKVEHYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AXM1-1", "uniprot_id": "CHSTA_DANRE", "id": "Q6AXM1-1", "name": "Carbohydrate sulfotransferase 10", "aln": "MRRHWLLVGACGWVLLILMFVSKFINFSFRIPGDYAGRSEIFVWTLSSVTTKLP-SVVWPEKGASQPYILSSVSPSVVEPIDWHLVNEKRLEQLSTVCSNSSIWNLTHTTVRKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGKFSKVEAIPENLVHDHERNGLPRLSSMTDTEIHQRLNSYFKFFIVRDPFERLISAFKDKFVKNPRFEPWYKHDIAPAIVRKYRRSHHDDSESVGLRFEDFVRYLGDKTGRQHLDRQFGDHIIHWLTYAELCAPCDISYNVVGHHETLELDAPYILKSAGIAGLVSYPSIPPGITRYNRTKVERYFSGISQRDIRRLYARYQGDFSLFDYPKPAFLLN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::***:.** **::::*..****.::*: *. *:.:.*:.. * . . ** . .* . *.. * :*** : ..* :.:: **:** * ************************************* **.:* ****:*****:********::. *::**::***********************:********:*:***.*:****: : :*: *::********** . :: ** *********:**.:*****:* *.*:******* *******.*** *****:****** *******:** ***:*********::***.**.* ** ****", "identical_positions": 226, "similar_positions": 78, "identity": "61.75%" }, { "cls_id": "homologset.agr.MGI:2138297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJS5-1", "uniprot_id": "SH3B4_RAT", "id": "Q9JJS5-1", "name": "SH3 domain-binding protein 4", "aln": "MAAQRIRAANSS-GLPRCKSEGTLIDLSEGFSETSFNDVKVPSPSALLVDNPTPFGNAKEVIAIKDYCPNNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMGYIPSSYVQPLNYRNSTLSDSGMIDNLPDSPDEVAKELDLLGG-WTDDQKQSGRPYSNN-PFWNGVRTNPFLNGNA-----QPSMDELNPKSTVDLLLFDTGTSSFTESSSATTNSTGNIFDELPATNGIHLEQPVKRDNPFFRSKRSYSLSELSVLQAKSDAPPTSS-FFTGLKSPAPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQSPGWGQTQAVETNIVCKLDSSGGSVQLPDTSISIHVPEGHVAPGETQQISMKALLDPPLDLNSDRSTSISPVVEVKLSNLEVSTFIILEMKVSAEVKGDIFSKSTVVLQCLRSDSKEGPYAPIPLAYSYGDTIQVQLDNLEPCMYLAIVAQGSNILYPSTVWDFIHKRVTVGLYGPKHIHPSFKTVVTIFGHDCAPKTLLVTEVTRQAPSPAPVALQLWGKHQFILSRPQDLRVCMFSNMTNYDVKSNEQAKVVRGFQMKLGKVSRLIFSVISQNPNELSDFTLRVQVKDDQDTILTQFCVQTPQPPPKSAIKPSGQRRFLKKNEVGKIILSPFVVTTKYPTFQDRPVSSLKFGKLLKTVVRQNKSHYLLEYKKGDVVALLSEERIRLKGQLWTKEWYIGYYQGKVGLVHTKNVLVVGKARPSLFSGPELSTSVLLEQILRPCKFLTYIYASVRTLLMENISSWRAFADALGYGNLPLTFFCRAELDSEPERVASVLEKLKEDCNNPDNKDRKSFQKELVMALLKMDCQGLVVRLIQDFVLLTTAVEVAQRWRELAEKLAKVSKQQMDAYESPHRDRNGVVDSEAMWKPAYDFLLTWSHQIGDSYRDVIQELHIGLDKMKNPITRRWKHLTGTLILVNSLDILRAAAFSPADHDDFVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921I6-1", "uniprot_id": "SH3B4_MOUSE", "id": "Q921I6-1", "name": "SH3 domain-binding protein 4", "aln": "MAAQRIRAANAS-GLPRCKSEGTLIDLSEGFSETSFNDVKVPSPSALLVDNPTPFGNAKEVIAIKDYCPNNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMGYIPSSYVQPLNYRNSTLSDSGMIDNLPDSPEEVAKELDLLGGGWTDDQKESGRPYSNN-PFWNGVRTNPFLNGNA-----QPSTDELNPKSTVDLLLFDTGTSSFTESSSATTNSTGNIFDELPATNGLQVEQPVKRDNPFFRSKRSYSLSELSVLQAKSDAPPTSS-FFTGLKSPVPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQSPGWGQTQAVETNIVCKLDSSGGSVQLPDTNISIHVPEGHVAPGETQQISMKALLDPPLDLNSDRSTSVSPVVEVKLSNLEVSTFIILEMKVSAEVKGDIFSKSTVVLQCLRSDSKEGPYVPIPLAYSYGDTIQVQLDNLEPCMYLAIVAQGPNILYPSTVWDFINKRVTVGLYGPKHIHPSFKTVVTIFGHDCAPKTLLVSEVTRQAPSPAPVALQLWGKHQFILSRPQDLRVCMFSNMTNYEVKANEQARVVRGFQMKLGKVSRLIFSVISQNPNELSDFTLRVQVKDDQDTILTQFCVQTPQPPPKSAIKPSGQRRFLKKNEVGKIILSPFVVTTKYPTFQDRPVSSLKFGKLLKTVVRQNKSHYLLEYKKGDVVALLSEERIRLKGQLWTKEWYIGYYQGKVGLVHTKNVLVVGKARPSLFSGPELSTSVLLEQILRPCKFLTYIYASVRTLLMENISSWRAFADALGYGNLPLTFFCRAELDSEPERVASVLEKLKEDCNNPDNKDRKSFQKELVMALLKMDCQGLVVRLIQDFVLLTTAVEVAQRWRELAEKLAKVSKQQMDAYESPHRDRNGVVDSEAMWKPAYDFLLTWSHQIGDSYRDVIQELHIGLDKMKNPITRRWKHLTGTLILVNSLDILRAAAFSPADHDDFVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0V3-1", "uniprot_id": "SH3B4_HUMAN", "id": "Q9P0V3-1", "name": "SH3 domain-binding protein 4", "aln": "MAAQRIRAANSN-GLPRCKSEGTLIDLSEGFSETSFNDIKVPSPSALLVDNPTPFGNAKEVIAIKDYCPTNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMGYIPSSYVQPLNYRNSTLSDSGMIDNLPDSPDEVAKELELLGG-WTDDKKVPGRMYSNN-PFWNGVQTNPFLNGNVP---VMPSLDELNPKSTVDLLLFDAGTSSFTESSSATTNSTGNIFDELPVTNGLHAEPPVRRDNPFFRSKRSYSLSELSVLQAKSDAPTSSS-FFTGLKSPAPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQSPGWGQTQAVETNIVCKLDSSGGAVQLPDTSISIHVPEGHVAPGETQQISMKALLDPPLELNSDRSCSISPVLEVKLSNLEVKTSIILEMKVSAEIKNDLFSKSTVGLQCLRSDSKEGPYVSVPLNCSCGDTVQAQLHNLEPCMYVAVVAHGPSILYPSTVWDFINKKVTVGLYGPKHIHPSFKTVVTIFGHDCAPKTLLVSEVTRQAPNPAPVALQLWGKHQFVLSRPQDLKVCMFSNMTNYEVKASEQAKVVRGFQLKLGKVSRLIFPITSQNPNELSDFTLRVQVKDDQEAILTQFCVQTPQPPPKSAIKPSGQRRFLKKNEVGKIILSPFATTTKYPTFQDRPVSSLKFGKLLKTVVRQNKNHYLLEYKKGDGIALLSEERVRLRGQLWTKEWYIGYYQGRVGLVHTKNVLVVGRARPSLCSGPELSTSVLLEQILRPCKFLTYIYASVRTLLMENISSWRSFADALGYVNLPLTFFCRAELDSEPERVASVLEKLKEDCNNTENKERKSFQKELVMALLKMDCQGLVVRLIQDFVLLTTAVEVAQRWRELAEKLAKVSKQQMDAYESPHRDRNGVVDSEAMWKPAYDFLLTWSHQIGDSYRDVIQELHLGLDKMKNPITKRWKHLTGTLILVNSLDVLRAAAFSPADQDDFVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVQ2-1", "uniprot_id": "SH34A_DANRE", "id": "Q1LVQ2-1", "name": "SH3 domain-binding protein 4-A", "aln": "MAAHRIRVTNNNNVLPRCKSEGTLIDIDEGVTEASLVDVKVPSPSALRLAPSTSFGTAREVVAIKDYCPSSFTTLKFSKGDHLYVLDTSGGEWWYAHNNREMGYIPSTYVQPINYRNSSLSDSGMIDNLGDCSEEGAKELDLLGE-WTGVCLKPSLPYDNNNPFSMLSSTNPFLNGSMDDVLDQNSNEKPNQCNSMDLLFFDLPSAPISTTSNTKGYSIS-GFDGTSTSADLEALQMLRKDNPFFRSKRSYSLSELSTLQAQSNPPLPSSGFFTGLKAPSPEQFQNREDFRTAWLNHRKLARSCHDLESLGQNPGWGQTQPVETNIVCKLDSCGGAVQLPDTNISIHVPEGHVAVGDTQQISMKALLDPPLELNNDRCSTVSPVVEIKLSNMEIKSFITLEMKVSVMTR---TESPMAEIVCVRSDCKEGPYSPVPQAYIYGDTIQVQLDNLEPCMYVAVVVQAKHVSFSSNVWNHMVKKVTLGLYGPKHIHPSFKTVVAIFGHDCAPKTLLVSEVGKQAKSAPPVSLQLWGKHQFVLSRPQDLQIGMYSNMSNYEVKANDQARVVRGFQIKLGKVSRLIYMISSRKADEISDFTLRVQVKDDQDCILAQFCVQTPQPPPKTGMRNNGQRRFLKKKEVDKIILSPLAITTKYPQFQERCITNLKFGKLIKTVIRQTKNQYLLEYKKGDIIALLSEEKIKLKGQLWTKEWYIGYYQGKIGLVHVKNVLVLGKVKPIYFCGPDLTTTMLMEQILKPCKFLTYIYASVRTILMENLGNWRAFADALSYVNLPLTYFCRAELDSEPERVASVLEKLKEDCLNMETKEKKSFQKELMMALLKMDCQGLVARLIMDFVLLTTAVEVAPRWRDLAEKLAHVSKQQMEAYEAPHRDKTGMVDSEAMWKPAYDFLLTWAAQIGDSYRDVIHELHMGLDRMKNPITKRWKHLTGTLILVNCLDLLRSSAFSPAPQDDFAI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***.:* . ************:.**.:*:*: *:******** : .*.**.*:**:*******..***************************. *******:****:*****:********** *..:* ****:*** **. .. *.** ** *******. * :: * .::***:** ::.:: :*.:. * . ** ..: .:. :::*****************.***:*:.* .** ******:* *****.*********************: ***.*******.***********.**:******.*********** *:**************:**.**. ::***:*:****:*:.: * ******. : ... . : *:***.***** .:* ***:*.**.*******:*:*.:. : :.*.**:.: *:**:****************:*************:** :** ...**:*********:*******:: *:***:**:**:.:**:******:*********: : *::.:*:*************: **:************:.:: .********:**.******:. ***** **:* ::.******:***:**.*.:********* :******:::*:***************::****.*****:*:.:* .**:*:*::*:****:**************:****:..**:*****.* *****:************************ * :.*::*******:************.*** ************ ***:******:******:***:****:.*:*****************: **********:***:***:******:*************.**:**::***** :***.*", "identical_positions": 666, "similar_positions": 205, "identity": "68.66%" }, { "cls_id": "homologset.agr.MGI:2138299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJT0-1", "uniprot_id": "ASHWN_RAT", "id": "Q5RJT0-1", "name": "tRNA-splicing ligase complex subunit ASW", "aln": "MAGDVGGRS--------CTDAELLLHPELLSQEFLLLTLEQKNIAVENDVRVNKDNLTDLYVQHAIPLPQRDLPKNRWGKMMEKKREHHEGKNDTKRGSAVDGLRKRPLIVFDGSSTST-SIKVKKTENG----ADDRLKPPAQTGSTSDSLRKSPNSSSRIAPLVLYSSLPMNNKMEHNNNDTKQNHDLTHRKSPSGPVKSPPLSPVGTTPVKLKRAAP-KEEAEATNHLKPPEAKRKIQHVTWP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922M7-1", "uniprot_id": "ASHWN_MOUSE", "id": "Q922M7-1", "name": "tRNA-splicing ligase complex subunit ASW", "aln": "MAGDVGGRS--------CTDAELLLHPELLSQEFLLLTLEQKNIAVENEVRVNKDNLTDLYVQHAIPLPQRDLPKNRWGKMMEKKREHHEVKNDTKRSSAVDGLRKRPLIVFDGSSTST-SIKVKRTENG----ADDRLKPLAQIGSTSDAFWKSPNSSSRISPLVLFSNLPVNHKMEHNNNDTQQNHDLMNRKSPSGPVKSPPLSPVGTTPVKLKRAAP-KEEAEATNHLKPPEVKRKIQHVTWP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVC5-1", "uniprot_id": "ASHWN_HUMAN", "id": "Q9BVC5-1", "name": "tRNA-splicing ligase complex subunit ASW", "aln": "MAGDVGGRS--------CTDSELLLHPELLSQEFLLLTLEQKNIAVETDVRVNKDSLTDLYVQHAIPLPQRDLPKNRWGKMMEKKREQHEIKNETKRSSTVDGLRKRPLIVFDGSSTST-SIKVKKTENG----DNDRLKPPPQASFTSNAFRKLSNSSSSVSPLILSSNLPVNNKTEHNNNDAKQNHDLTHRKSPSGPVKSPPLSPVGTTPVKLKRAAP-KEEAEAMNNLKPPQAKRKIQHVTWP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32LR5-1", "uniprot_id": "ASHWN_DANRE", "id": "Q32LR5-1", "name": "tRNA-splicing ligase complex subunit ASW", "aln": "MASHRTDRTKNPTSNGDVSKVDLLLHPELLSQEFIQLMLQERNIAVSDPE--DRDRLTGLYLQHVIPLPQRELPRSRWGKRMEKSRP--RLSSSSTHSSSTDSGRKRPLIVFDGSSTSTGCVKLKKPDSSSAPVTTDRLKPPVSSVSLTNPIRKLSGASTNCSSSNFSNRTPVSSSGAIP-------------KSPSNHSNSSVHSNNATS--KLKRTSPSKGEPDTAKDIKSPETKKKIQHITWP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.. .*: :. :************: * *:::****. ::* **.**:**.******:**:.**** ***.* . ...:.:.*:.*. *************** .:*:*:.:.. ***** . ::.: * ..:*: :. : . *:. . ****. :*. * .*: ****::* * *.:: :.:*.*:.*:****:***", "identical_positions": 95, "similar_positions": 74, "identity": "38.62%" }, { "cls_id": "homologset.agr.MGI:2138302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16666-1", "uniprot_id": "IF16_HUMAN", "id": "Q16666-1", "name": "Gamma-interferon-inducible protein 16", "aln": "MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEG----------------------------------AEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPK--TVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEEST-----------------------------------------------------------------------------------------------VSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYG-------------------------------------------VFMLHKKTVNQKTTIYEIQD------DRGKMDVVGTGQCHNIPCE-----EGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDP---KSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLT--------------------------TLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSSMETSPDFFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q3L4-1", "uniprot_id": "E9Q3L4_MOUSE", "id": "E9Q3L4-1", "name": "", "aln": "MVKEYKRIVLLKGLECINKHHFSLFKSLLARDLSLERDNQEKYSTIQIANMMEEKFKPDAGLGELIEFCEKVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLTSERGETSATQEETSTAQGETSTAQAGTSTAQAGTSTAQAGTSTAQTKRKQITKSEGEKKKKLTQEQAQLSEPLGTDRKKDEDCLQTPLMAPPTPPSSSSNKKQKNTTIPKHGIIKTRGPQEIHQLVEFSSSSNFPAVSELPTFEGLSAIPSSRLQSSQKPLEAHLDLKMSPSSSRSPCHNLSVSLTSDSNVHLNSNAHSIQSSGAQVPYVPSATGFSNVRVPLMPSKTVSCSSIAPHMSLIKVPSSIQDLHLPTQEAFSSTEDPHNQAIASKNLQTTKMPPTTLTSKAQLLKMPSSATSSSSVQVSHTLATVSRSTSVKQILQTTRSSSIQILNSATVKASKNVQASQVSLPTEPNYFQASVAPPSATPSSSTSLLVPLSKATSRAQSTQIHPERESICVQAHRAPSSTVSRNKCTTQLTQGAASGTGKAFSLPEVKASMKVQAPQVSSPTASMSILNPNATPPTTSSNLLAPHATSSTTYSILLAPYATLSTASSNLLAPQATVSTASSNLLAPHATLSTTSSNLLAPHATLSTTSSNLLAPHATSSTASSNLLAPQATLSTPSNSLLAPHATLSTTSSNLLAPHATSSTASSNLLAPHATSSTASSNLLAPHATLPTASSNLLAPQLCPVTASRALSAIPVPSATVHSSPSWTPRRGTVPKEPSREEGHHQGPKQVMVLKVTEPFTYDLEEDKRMFHATVATETEFFRVKVFDTALISKFIPRNIIAISDYFGCNGFLEIYRASCVSDVNVNPTMVISNTLRQRANATPKISYLFSQAKGTFVSGEYLVIKKTERNKAIYYGVKDNTGKMEVMVYGRLTNITCEPGNKLRLVCFELN-LIEDGLQLKSVRHSYMQVINARR--------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 251, "similar_positions": 284, "identity": "25.13%" }, { "cls_id": "homologset.agr.MGI:2138319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M5H6-1", "uniprot_id": "F1M5H6_RAT", "id": "F1M5H6-1", "name": "", "aln": "MRFGSKMMPMFLTVYLSNSEQHFTEVPVTPETVCRDVVDLCKEPGE-SDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPNRDIVSGPRSQDAGVKRNGVKVPGEHRRKENGVNSPRLDLTLAELQEMASRQQQQIEAQQQMLATKEQRLKFLKQQDQRQQQQ-AAEQEKLKRLREIAESQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNSLFQQKQRELVLAVSKVEELTRQLEMLK------------NGRIDGHHDN-QSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSPDGNPPQQAVSAPSRVAAVGPYMQSSTMPRMPSRPELLGKPALPDSSLVMQSAEGPMKIQTLPNMRSGAASQSKGPKAHSASSDWNPSSTDLLPSQGS-------GSALDQVDEGEIALREKEKKVRPFSMFDTVDQCAPPPSFGTLRKNQSSEDILRDAQTVNKNVAKVPPPVPTKPKQINLPYFGQTAQSSSDVKPDGNPQQLPIAATSMGAKLKPAGPQARVLLSPSA------PSGGQDQVLSPASKQESPPAAAVRPFTPQP--SKDTFPP-AFRKPQTVAASSIYSMYTQHQVPGKNFQQAVQSASTKTHPRGPHFSSVYGKPVIAAAQNPQQ------HPENIYSCSQGKPGSPEPETEPVSSVHESHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSPSSVTVNPESPIEIPNPYLHVEPEKEAGSLVPEPLSPEDMGSASTENSDMPAPPPGLECVSEGVP-DNSTTLQDNTEGTN-PEAPHLLEVYLEEYPPYPPPPYPSGEPEVSE-EDSARMRPPEVTGQVSLPPGKRTN---LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYQPQHDDELLLKEGDCMAVVRREDEDETEWWWAR-LNDKEGYVPRNLLGLYPRIKPRQRSLA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG79-1", "uniprot_id": "ASPP2_MOUSE", "id": "Q8CG79-1", "name": "Apoptosis-stimulating of p53 protein 2", "aln": "------MMPMFLTVYLSNSEQHFTEVPVTPETICRDVVDLCKEPGE-NDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPNRDIVSGPRSQDPSVKRNGVKVPGEHRRKENGVNSPRLDLTLAELQEMASRQQQQIEAQQQMLATKEQRLKFLKQQDQRQQQQ-AAEQEKLKRLREIAESQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNSLFQQKQRELVLAVSKVEELTRQLEMLK------------NGRIDGHHDN-QSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVSELRDRLWKKKAALQQKENLPVSPDGNLPQQAVSAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLLMQSAEGPMKIQTLPNMRSGAASQSKGSKAHPASPDWNPSNADLLPSQGSS-VPQSAGTALDQVDDGEIAVREKEKKVRPFSMFDTVDQCAAPPSFGTLRKNQSSEDILRDAQAVNKNVAKVPPPVPTKPKQIHLPYFGQTAQSPSDMKPDGNAQQLPIAATSVGAKLKPAGPQARMLLSPGA------PSGGQDQVLSPASKQESPPAAAVRPFTPQP--SKDTFPP-AFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTQPRGPHFSSVYGKPVIAAAQNPQQ------HPENIYSCSQGKPGSPEPETETVSSVHESHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSHPSKSPGSVTVNPESSVEIPNPYLHVEPEKEVGSLVPEPLSPEDMGSASTENSDVPAPSAGLEYVSEGVT-DSSTNLQNNVEETN-PEAPHLLEVYLEEYPPYPPPPYPSGEPEVSE-EDSARMRPPEITGQVSLPPGKRTN---LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQHDDELLMKEGDCMTVIRREDEEEIEWWWAR-LNDKEGYVPRNLLGLYPRIKPRQRSLA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13625-1", "uniprot_id": "ASPP2_HUMAN", "id": "Q13625-1", "name": "Apoptosis-stimulating of p53 protein 2", "aln": "------MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGE-SDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQ-VAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLK------------NGRIDSHHDN-QSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSI------PSVGQDQTLSPGSKQESPPAAAVRPFTPQP--SKDTLLP-PFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQ------HPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKS-ASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVP-DNSPNLQNNPEEPN-PEAPHVLDVYLEEYPPYPPPPYPSGEPEGPG-EDSVSMRPPEITGQVSLPPGKRTN---LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWAR-LNDKEGYVPRNLLGLYPRIKPRQRSLA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R419-1", "uniprot_id": "F1R419_DANRE", "id": "F1R419-1", "name": "", "aln": "------MMPMFLTVYLSNNDQHFSEVPITAETVCADVLQLCREPGENSSCYLSEVWRGSERVVGENEKMMDLLLQWGQQRPEVRFFLRHGRAASQ--PSDSRTQ----KRNGVKKP-ADRRLENGVNGPWMDMTLAELQEMASRQQRQIDSQQQLLSTKEQRLRYLQQQEQRQAQS-SSEQKKLLQLRETLEQQEAQLKMVRALKGQVEQKRLSNGKLVEQVEQMNNLLHQKQKELVVAVAKVEELSKQLETLK------------SGQMDAMNSN-HSSVAELDRLYRELQMRKNLNVEQNAKLQQQRENLNKRNQEVANMDKRVSELRERLWKKKAALQQKENLPLPPDGQAPPQTP--GSRVAAVGPYIQSSTMPRGPDRQDLPIKHNYP--EFTATAGHQDRSAQPGAGLHSGKASSKLANWSLANAKSGNNHVTSSLPRMVS--------QASKSQDNTDVQKRD--PRVRPVSMFESTDLPAA-----ALRKNQSSEDLVRDAQSAVKTIVKVPPPVPSKPKQANFPSGGLMGLG------------------------KNTGTYPGKSASPQP------PAGPQTGTLP--SKLEAPPAATVHPFSPDPPGAKDTGGQ-MLLKPQTVTASSIYSMYTQQPSSGKATQQSIQGALSRAQTRTGHFISVYGKPVTSAGQPSQTP-----HPENPYLDPPS-VSETLTDHSPAEPISETPETERIPRPLSPTKLLPFISNPYRHQSDLDLEALRKKLYNAPRPLKKRSSITEPEGPGGPNIQKLLYQKTTLAAMETVSPPGEEEKE----------TLAKPQGYDAETPEVPEETLPEFPIAP------EVEAEDVPPPPP----PHPAPK-IDASIIIPPPQPES-PPPPPPPDSFMEDFPPYPPPPYPSSAEQDNP-DDTFNMKPPEVTGQVPFPPGKRTN---LRKSGSERIDHSMRVRFNPLALLLDSSLEGEFDLVQRVIYEVEDPSQPNDEGITALHNAVCAGHTEIVKFLVQYGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNRGVVYGLWDYEAAQEDECSFREGDCMSVIRREDELETDWWWVR-CGGAEGYVPRNLLGLYPRIKLRQRSLA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QWN1-1", "uniprot_id": "F1QWN1_DANRE", "id": "F1QWN1-1", "name": "", "aln": "------MMPMFLTVYLSNSDKHFTELPITPETLCRDVLDMCKEPGE-VDCYLAEMWRGSERVIGDSERIIEVLQRWGQQRAEVRFFLRHDRAPGHD-TGGHRTPESLAKRSNAVKD---RLMENGMAAPHMDITLSELQEMASRQQQQINAQQQLLATKEQRLRFLKLQDQRQQQQQVSEQEKLRQLRENAENQEAKLRRVRALKGQVEQKRISNSKLVEEIEQMNGLFQQKQRELVVAVSRVEELSRQLDVLR------------SGKMDMPHEAGPSSSGELERLYKELQLRNKLNQEQSAKLQQQRENLNKRNVEMAAMDKRVAELRERLWKKKAALQQKENLPQPSEGQNPQSVG--PSRVAAVGPYIQTTPAPPLPPKQEILVKPAYPDGTATLPK---PLPKPTTGGFLTGKISKISDLFSSTETSKSSHVHSSTLPRMTS---------HGSQEKDPEVDLRP-----PPL----------------PLRKNQSSEDLLRDSQSAGRTFEKVPPPVPSKPKPALSGQSTFSKLP------------------------YSTGTFPGKARSANQKPPMPLPSHNNTLPLPLPPKPDTLPAATVRPFTSDTLAGKDTSTPTTLHKPQTVAASSIYSMYTQQSTLGKGYQG--QSTLTRSQPR------LYGKPVIPSSVGQQSFIQDFSHIEKICGLDGDQVDQGSSNTAPASSSVEGQEAERVPRPLSPTKLLPFLSNSHRLQSDVDLEALRKRLHNAPRPLKKRGSITESEGPGGPNIQKLLYQKTTLAAMETIAPAAFFPAE------GEDGCRPVPNESTRPQEGHHDNTIPECEREEE-----ELTPPPLPPRSPILDDNSNFSTGLNEPQLKEEQEVYG-PAAP---EPYVEEYPPYPPPPYPSMTEQEGPGEDSINMKAPEVTGQVMLPPGKRTN---LRKTGSERINHGMRVRFNPLALLLDSSLEGEYDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQYGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVYAMTYSDLQTAADKCEEMEEGYAQCSQFLYGVQEKMGIMNRGVVYALWDYDGESPDELSFKEGDCLTVLRREDGEETEWWWAR-CADNEGYIPRNLLGLYPRIKPRQRSLA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BG1-1", "uniprot_id": "Q86BG1_DROME", "id": "Q86BG1-1", "name": "", "aln": "----------MLTCVCRPVSGNLPKMPPASLMPAHRASASSASSSTSSTASLAFVS-PTRGVVVTSEPKLNVPSRLTS---------------------------------------------------------AELRAMALRQQQQIDSQHQLLATKEQRLRFLKSQEVRSAVA-SAEGERLRRLRERVEAQESKLRRLRALRGQVDLQKTYNVTLSNDLDSIRALFSEKEKELSLAVAKVEALTRQLEELRRDRRCPVNILTAAGNGVGGQSLPPQASRELEKLRRELMYRNQLSLQQDARLHMQREALQQRQAELRSTDQRIYELQTRLQRKKQANTHHQQQQQQQQQHQQQQHQQQHQQTTVQQQQQQQQQLHVQSAQLLAAAAAATAQQQQQHQQHQQQQQQQQQQSASNLGKHGGVAALKQQLLQKQVNQLAAAAAAAAAG------RARGNVAAVEPFIHTPQKSTITSTASYLSGGMKHAAATANTNQQNQLIQDLTHVKLGQNSGFFAGSVPVPVASSSCESDESKLAKKLLAAP--------------AKTEAELRKQAQTEAMDSTTHIYAEVGPKKRDREAAAAAAAAAAAAAAAAQAAAEAANQAATAAAASAISPPATANASKIPKSTTSSSSSASALISKLNQQATAKESQDQQQSQAKKNEISVTSETLSER-----NTQQQLTVHSMPLGAISKSVALAVSNASKPLQVQVSNVAVPPRKPISSVAPNSVSSGSSIPKMITYSPKVNR-VAPNVVMTDPRPALPPKPSKMSPTEQPSPVEANTSGSAGGAGS---------GAASASTANKTQTATFGLQSLNINDNLPIKAKPLTIRKQPLFEQPRLKSSQSSSNGQQKPPLLQLQNQRKSEPSARQPTENLPDTSPQHSPSSESSADETDRMVAPSITTSQQETSTSATSTTTTVTTSNIKERTGNGKPKLGRRVSFDPLALLLDASLEGELELVKKTAMQVANPSAANDEGITALHNAICAGHIDIVKFLVEFGCDVNAQDSDGWTPLHCAASCNNLSMVKFLVESGACLFASTLSDHETPAEKCEEDEEGFDGCSEYLYSIQEKLGILHNGDVYAVFSYEAQNGDELSFHVNEPLIVLRKGDDAENEWWWARNAAGEEGYVPRNLLGLYPRVPPHSPHFSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** . ::.::* :. . . . ... . *: : :. : .* ::: : . :**: ** ***:**::*:*:*:******::*: *: *. :* ::* :*:* * **::*: :***:*:*: :: * .* ::::.:. *: :*::** :**::** *::**: *: *. :. .: **::* :** *::*. :*.*:*: *** *::*: *: *:*: **: ** :** * :::: : : . .:.:. * . : . . . . : . : . . . . ::** :*: : . . *** .. . *. * : . . : .**:.:. : . . : : * *. **.* . *. .. : : ..: : : :. . : :: . . . . . ::.. *.: . .*. .: : . :. * : . :*:.. . *: .*: . . .. . : .. . :: : . . . : : . * . : : * :.*.. .* : * : .. .. . *. .::*. : . ** *:*******:***** :**:: :* :** .***********:**** :******::* :*** ****************:.: ********.::* * ** :*.*:**** ***: **::**.:***:**::.* :*.::.*: ** :: .: : :::: * * :***.* . ***:**********: :. :: ", "identical_positions": 224, "similar_positions": 290, "identity": "19.1%" }, { "cls_id": "homologset.agr.MGI:2138327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHE4-1", "uniprot_id": "PHLP1_MOUSE", "id": "Q8CHE4-1", "name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "aln": "----------------------------------------------------------------MEPAAAAPAQRLADPTGEDQA-LAAAAAE-----------------GGRCPDPALSAAAPSGGNGG--AAREEAPCEAPPGPLPGRAGGTGRRRRRGAPQPAAGGAAPVPAAGGGANSLLLKRGRLKRNLSAAAAASSSSSPSSASSAAG-----GLPASCSASASLCTRSLDRKTLLLKHR---QLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDTTAAEVAARLLQLG-------------------------------------------------------HKGGGVVKVLGYGP------PPAAAPAASDQTLDGEHGRDVEPPPSSGTVGAVRGPARAPPADLPLPGGAWTRCAPRISPAPSDSSPGELFAG--------GPGSPPRAPRP-ASDTESFSLSPSAESVSDRLDPYSSGGGGSSSSSEELEADPA--------MPHRPGRPAQPRP-PSPKTSALLQPKAPTGVDSTGVIAGEGPGDDKAMAAAAPDVPLSTSGRIRETVQKTS----PPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLP-------VNRWTRRQVILCGTCLIVSSVKDSVSGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQN------------FLRQTPTLPAARGLGELQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALREVPAAVGDMQNLQTFLLDGNFLQSLPAELESMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCVETLRLQALRRMPHIKHVDLRLNILRKLMADEVDFVQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNVCGYFLKALYASS---NELAQLDVYPVPNYLSYMDVSRNCLESVP-EWVCESRKLEVLDIGHNQICELPARLFCN--SSLRKLLAGHNRLARLPERLERTS-VEVLDVQHNQITELPPNLLMKADS-LRFLN----ASANKLETLPPATLSEETSSILQELYLTNNCLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIP-TTIMNCRRMHTVIAHSN-CIEVFPEVMQLPEVKCVDLSCNELSEIT-----LPENLPP-KLQELDLTGNPRLALDHKSLELLNN--------------------IRCFKIDQPSAG-DASGAPAVWS-HGYTEASG--VKNKLCVAALSVNNFRDNRE----ALYGVFDGD--RNVEVPYLLQCTMSDILAEELQKT-----KNEEEYMVNTFIVMQRKLG---------TAGQKLGGAAVLCHIKPDPVDLGGS-FTLTSANVGKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAVR-NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPSGVLN---ESSPAYPNEQRCMLHP---VCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFSNGSRVEVEVDIHCSRAKEKERQQ---HLLQVPAEASDEGIVISANEDESGLSKKADFSAVGTIGRRRANGSVAPQERS------------------------------------------------HNVIEVAADAP-LRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQQQQLPPPPQPPQP--QPQPQPQPQPQPQRHFQMDHLPDCYDTPL---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTR8-1", "uniprot_id": "PHLP1_RAT", "id": "Q9WTR8-1", "name": "PH domain leucine-rich repeat protein phosphatase 1", "aln": "----------------------------------------------------------------MEPAAAAPAQRLADPTGEDRAPAAAAAAE-----------------GGRSPDSVLSAAAPSGGNGG--AAREEAPCEAPPGPLPGRAGGTGRRRRRGVPQPAAGGAAPVTAAGGGANSLLLRRGRLKRNLS--AAASSSSSPSSASSAAG-----GLPASCSASASLCTRSLDRKTLLQKHR---QLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDTTAAEVAARLLQLG-------------------------------------------------------HKGGGVVKVLGHGP------PPAAAPAASDQTPATELGRDVEPPPSSSTVGAVRGPARAPPADLPLPGGAWTRCAPRVNPAPSDSSPGELFAG--------GPCSPSRAPRP-ASDTESFSLSPSAESVSDRLDPYSSGGG-SSSSSEELEADPATVLTGPSGPPHHPVRSSQPRP-PSPKTSALLQPKAPTGVDGTGLVVGEGPGDDKAVAAAAPGVPLWTPGRIRETVQKTSS---PPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLP-------VNRWTRRQVILCGTCLIVSSVKDSSSGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQN------------FLRQNPSLPAARGLGELQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALQEVPAAVGAMQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCMETLRLQALRRMPHIKHVDLRLNILRKLITDEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNICGYFLKALYASS---NELVQLDVYPVPNYLSYMDVSRNCLESVP-EWVCESRKLEVLDIGHNQICELPARLFCN--SSLRKLLAGHNRLARLPERLERTS-VEVLDVQHNQIIELPPNLLMKADS-LRFLN----ASANKLETLPPATLSEETSSILQELYLTNNSLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIP-TTIMNCRRMHTVIAHSN-CIEVFPEVMQLPEVKCVDLSCNELSEIT-----LPENLPP-KLQELDLTGNPRLALDHKSLELLNN--------------------IRCFKIDQPSAG-DASGAPAVWS-HGYTEASG--VKNKLCVAALSVNNFRDNRE----ALYGVFDGD--RNVEVPYLLQCTMSDILAEELQKT-----KNEEEYMVNTFIVMQRKLG---------TAGQKLGGAAVLCHIRHDPVDLGGS-FTLTSANVGKCQTVLCRNGKPLSLSRSYTMSCEEERKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVR-NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSVGGSMPPPSPGIFPPSVSMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPSGALS---ESSPAYPSEQRCMLHP---VCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFSNGSRVEVEVDIHCSRAKEKERQQ---HLLQVPAEASDEGIVISANEDESGLSKKTDISAVGTIGRRRANGSVPPQERS------------------------------------------------HNVIEVATDAP-LRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQQQQQQQQQQPPPPPQPPQAQAQAQAQAQRPFQMDHLPDCYDTPL---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60346-1", "uniprot_id": "PHLP1_HUMAN", "id": "O60346-1", "name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "aln": "----------------------------------------------------------------MEPAAAATVQRLPELGREDRASAPAAAAAAAAAAAAAAAALAAAAGGGRSPEPALTPAAPSGGNGSGSGAREEAPGEAPPGPLPGRAGGAGRRRRRGAPQPIAGGAAPVPGAGGGANSLLLRRGRLKRNLSAAAAAASSSSSSSAAAASHSPGAAGLPASCSASASLCTRSLDRKTLLLKHR---QTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDTTAGEVAARLLQLG-------------------------------------------------------HKGGGVVKVLGQGPGAAAAREPAEPPPEAGPRLAPPEPRDSEVPPARSAPGAFGGPPRAPPADLPLPVGGPGGWSRRASPAPSDSSPGEPFVG--------GPVSSPRAPRPVVSDTESFSLSPSAESVSDRLDPYSSGGG-SSSSSEELEADAASAPTGVPGQPRRPGHPAQPLPLPQTASSPQPQQKAPRAIDSPGGAVREGSCEEKAAAAVAPGGLQSTPGRSGVTAEKAPPPPPPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLP-------VNRWTRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQN------------FLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLDICGYFLKALYASS---NELVQLDVYPVPNYLSYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCN--SSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQLLELPPNLLMKADS-LRFLN----ASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIP-TTIMNCRRMHTVIAHSN-CIEVFPEVMQLPEIKCVDLSCNELSEVT-----LPENLPP-KLQELDLTGNPRLVLDHKTLELLNN--------------------IRCFKIDQPSTG-DASGAPAVWS-HGYTEASG--VKNKLCVAALSVNNFCDNRE----ALYGVFDGD--RNVEVPYLLQCTMSDILAEELQKT-----KNEEEYMVNTFIVMQRKLG---------TAGQKLGGAAVLCHIKHDPVDPGGS-FTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVR-NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPPGALS---ENSPAYPSEQRCMLHP---ICLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKEKQQ---HLLQVPAEASDEGIVISANEDEPGLPRKADFSAVGTIGRRRANGSVAPQERS------------------------------------------------HNVIEVATDAP-LRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQ---------PPPP-------PQLQPQLPRHYQLDQLPDYYDTPL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ07-1", "uniprot_id": "PHLPP_DROME", "id": "Q9VJ07-1", "name": "Protein phosphatase PHLPP-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKATR----KQADPYKSKLKVSASHSGPHP-----------LPVEVTAAEEEQAATFGQTSPQKLSLKGSQLG------------------------------------GSILIGN------------------------------------YNYLTQLEVCENEMEVLDLSSLAQLETLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELP-NWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLN----VSCNKLSTLP--RYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLP-EEVATLGQLRVLRCCNN-LLLCTPQLAKLAMLKVLDLSHNHLDRVN-----LLALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGN--NRAALPTTKIRQVSAQRNQNKTSGPWT-MGFAETPGSGDCRKLSVYQLRAANYGGSDE----ALYGMFEALEGRGRAAQEMSHLVPDLMKQEQMVKD-----SAVRDYMKFTLLAAQQQCG---------SVRSAALFHLTRTRAPSKVRPLKSKRYVLRMASTGGLDAYLIRRTSQLRLTKPDVIQKDQIHS----------------------------------MPDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIR-KEENSLLAAKRLVDIAQSFAAAESLSVIVVRFRHLGTDVDHLIRELKQSVRKKPQPVSLPLSSGSVCKRTCCDRSNACRHRAIEQEPLAGRSSPSGQSDRDLLAKDKDDEFVLA---HARVLQEEQQLEMLDETESVSESVLSEEQFKCWEYMLEQNTQLLFDKELNTISKSFTKQRTVPNAIMAATVLPERNDFTS---NLMRTVTNKFISTSTPQLPQPITTSVPLGSYHQVKQAPPGHFGSALSFQQAH------------------------------------------------SYGYNLFDAKPRPKFHGGTVKRSAGPNSAYFGSLQRLMPYNFEYDFAVTQERERNILDEE----------------EHDDDDFNEHESRMRKYWGVATTEL---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08678-1", "uniprot_id": "CYAA_YEAST", "id": "P08678-1", "name": "Adenylate cyclase", "aln": "MSSKPDTGSEISGPQRQEEQEQQIEQSSPTEANDRSIHDEVPKVKKRHEQNSGHKSRRNSAYSYYSPRSLSMTKSRESITPNGMDDVSISNVEHPRPTEPKIKRGPYLLKKTLSSLSMTSANSTHDDNKDHGYALNSSKTHNYTSTHNHHDGHHDHHHVQFFPNRKPSLAETLFKRFSGSNSHDGNKSGKESKVANLSLSTVNPAPANRKPSKDSTLSNHLADNVPSTLRRKVSSLVRGSSVHDINNGIADKQIRPKAVAQSENTLHSSDVPNSKRSHRKSFLLGSTSSSSSRRGSNVSSMTNSDSASMATSGSHVLQHNVSNVSPTTKSKDSVNSESADHTNNKSEKVTPEYNENIPENSNSDNKREATTPTIETPISCKPSLFRLDTNLEDVTDITKTVPPTAVNSTLNSTHGTETASPKTVIMPEGPRKSVSMADLSVAAAAPNGEFTSTSNDRSQWVAPQSWDVETKRKKTKPKGRSKSRRSSIDADELDPMSPGPP-SKKDSRHHHDRKDNESMVTAGDSNSSFVDICKENVPNDSKTALDTKSVNRLKSNLAMSPPSIRYAPSNLDGDYDTSSTSSSLPSSSISSEDTSSCSDSSSYTNAYMEANREQDNKTPILNKTKSYTKKFTSSSVNMNSPDGAQSSGLLLQDEKDDEVECQLEHYYKDFSDLDPKRHYAIRIFNTDDTFTTLSCTPATTVEEIIPALKRKFNITAQGNFQISLKVGKLSKILRPTSKPILIERKLLLLNGYRKSDPLHIMGIEDLSFVFKFLFHPVTPSHFTPEQEQRIMRSEFVHVDLRNMDLTTPPIIFYQHTSEIESLDVSNNANIFLPLEFIESSIKLLSLRMVNIRASKFPSNITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLP---QSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTNASN-LQNLFLTDNRISNFEDTLPKLRALEIQENPITSISFKDFYPKN--MTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKL--TKLVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIRDFVDGMENLELTSLNISSNAFGNSSLENSFYHNMSYGSKLSKSLMFFIAADNQFDDAMWPLFNCFVNLKVLNLSYN---NFSDVSHMKLESITELYLSGNKLTTLSGDTVLKWSSLKTLMLNSNQMLSLPAELSNLSQLSVFDVGANQLKYNISNYHYDWNWRNNKELKYLNFSGNRRFEIKSFISHDIDADLSDLTVLPQLKVLGLMDVTLNTTKVPDENVNFRLRTTASIINGMRYGVADTLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRQLERYGDETDDNIKTALRFSFLQLNKEINGMLNSVDNGADVANLSYADLLSGACSTVIYIRGK--KLFAANLGDCMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVNNGKLDGVVDVSRAVGFFDLLPHIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARENSTDPLRAAAELKDHAMAYGCTENITILCLALYENIQQQNRFTLNKNSLMTRRSTFEDTTLRRLQPEISPPTGNLAMVFTDIKSSTFLWELFPNAMRTAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAFPTPTSGLTWCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNIIYQGLSVRMGIHWGCPVPELDLVTQRMDYLGPMVNKAARVQGVADGGQIAMSSDFYSEFNKIMKYHERVVKGKESLKEVYGEEIIGEVLEREIAMLESIGWAFFDFGEHKLKGLETKELVTIAYPKILASRHEFASEDEQSKLINETMLFRLRVISNRLESIMSALSGGFIELDSRTEGSYIKFNPKVENGIMQSISEKDALLFFDHVITRIESSVALLHLRQQRCSGLEICRNDKTSARSNIFNVVDELLQMVKNAKDLST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*.: : . .* * :. . .. : . : *. . * : * : *:: *.: :. :: * *:: : *::* . .: : :* : : :.: :..:* : : * :: .:*.: .:. : :.* * . * * : . . :. *::: *:: .: .: : *. . *. : . .: * : :.* : * : .*::*:::** :. : .: : :*** * :. : . ::.: .* : .:: :*. :. .*:. *.*. :*: *:::** :: :. . : : *: : .. :.. . : : :. : .: .. : .*:. : . : : . : .:: : . . : ::: ::: . : .. * *. * : * :. : .. . *.: : *: ** :::.. **. :.:: . * : :.* ** .* * ::.. :.:: : : : . . : . . . . . . : . : . : : . : :: : . . : : : * : .: . . * : . . : . : . . :: :. : . . . : : . : : . : : : * ", "identical_positions": 65, "similar_positions": 272, "identity": "3.19%" }, { "cls_id": "homologset.agr.MGI:2138334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M875-1", "uniprot_id": "A0ABK0M875_RAT", "id": "A0ABK0M875-1", "name": "Diacylglycerol kinase", "aln": "MKEMGQAETTQQEPCKPASAPTVYGGAVGWGGRPLGPAPPRLRPRHWAHPTPAPPRPPRRARWPGSMAAAAGAPPPGPPQPPPPPPPE-ESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTILKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNKEHFEPTQYSMDH---FSGTHNWYACSHARPTYCNVCREVLSGVTSHGLSCEVCKFKAHKRCAVRATSNCKWTTLASIGKDIIEDEDGIAMPHQWLEGNLPVSAKCIVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLVMKCPLGLCKVSVIPPTALNSIDSDGFWKATCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILAKLERASTKMLDRWSVMAYETKLPRQASSSTVTEDCSEDSEVQQILF-YEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSQESEVMAKKCSVLKEKLDSLLKTLDDESQASSS----LSNPPPTIAEEAEDGDGSG--------NICSSTGDHLVGSACP-SRPQIFRPREQLMLRANSLKKAIRQIIEHTEK----------------------------------------------------------------AVDE------------------------------------------------------------------QNAQTQEQQGFVLG------------------------------LSESEKKDLKTDNRVCT------------------------------------------------------------------------SSAHSESCVVAKGRSHRK-------------------------------------------------ASRTPCEKLMSKG-LSLGSSASLPPNTGSRDSLPALNTKILYPSVR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGMSGS----------------------------------------------------------------------LP--------------------------------------------------------------------GGSVISR-LLINADPFNAEPE--------NLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYRNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIKLQHHRIAQCRTVKISILGDEGVPVQVDGEAWIQPPGYIRIVHKNRAQTLTRDRAFENTLKSWEDKQK-----CELPRPPSFSLHP----EILSEEEATQMDQFGQAAGSLIHSIREIAQSHRDMEQELAHAVNASSKAMERVYGKPRAAEG-LNCSFVLEMVNNIRALRSETELLLAGK-MALQLDPPQKERLGAALVEMDQQLRKLTDTPWLCQPMEPGEEESLQQNVMLDLTKRSRSGKFRLVTKFKKEKNNKNKEVHSYLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSSPAAEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PUQ8-1", "uniprot_id": "DGKD_MOUSE", "id": "E9PUQ8-1", "name": "Diacylglycerol kinase delta", "aln": "------------------------------------------------------------------MAAAAGAPPPGPPQPPPPPPPE-ESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTILKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNKEHFEPTQYSMDH---FSGMHNWYACSHARPTYCNVCREVLSGVTSHGLSCEVCKFKAHKRCAVRATSNCKWTTLASIGKDIIEDEDGIAMPHQWLEGNLPVSAKCIVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLVMKCPLGLCKVSVIPPTALNSIDSDGFWKATCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILAKLERASTKMLDRWSVMAYETKLPRQASSSTVTEDFSEDSEVQQILF-YEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSQESEVMAKKCSVLKEKLDSLLKTLDDESQASSS----LSNPPPTIAEEAEDGDGSG--------NICSSTGDHLVGSACP-SRPQIFRPREQLMLRANSLKKAIRQIIEHTEK----------------------------------------------------------------AVDE------------------------------------------------------------------QNAQTQEQQGFVLG------------------------------LSESEKKDLKTDNRVCT------------------------------------------------------------------------SSVHSESCVIAKGRSQRK-------------------------------------------------ASRAPCEKLVSKG-LSLGSSASLPPGTGSRDSLPALNTKILYPSVR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGMSGS----------------------------------------------------------------------LP--------------------------------------------------------------------GGSVISR-LLINADPFNAEPE--------NLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYRNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIKLQHHRIAQCRTVKISILGDEGVPVQVDGEAWIQPPGYIRIVHKNRAQTLTRDRAFENTLKSWEDKQK-----CELSRPPSFSLHP----EILSEEEATQMDQFGQAAGGLIHSIREIAQSHRAMEQELAHAVNASSKAMERVYGKPRTAEG-LNCSFVLEMVNNIRALRSETELLLAGK-MALQLDPPQKERLGAALIEMDQQLRKLTDTPWLCQPLEPGEEESLQQNVMLDLTKRSRSGKFRLVTKFKKEKNNKNKEVHSNLGGPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSSPAAEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16760-1", "uniprot_id": "DGKD_HUMAN", "id": "Q16760-1", "name": "Diacylglycerol kinase delta", "aln": "------------------------------------------------------------------MAAAAGAPPPGPPQPPPPPPPE-ESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDH---FSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILF-YEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSS----LPNPPPTIAEEAEDGDGSG--------SICGSTGDRLVASACP-ARPQIFRPREQLMLRANSLKKAIRQIIEHTEK----------------------------------------------------------------AVDE------------------------------------------------------------------QNAQTQEQEGFVLG------------------------------LSESEEK---MDHRVCP------------------------------------------------------------------------PLSHSESFGVPKGRSQRK-------------------------------------------------VSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGMSGS----------------------------------------------------------------------LP--------------------------------------------------------------------GGSVISR-LLINADPFNSEPE--------TLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQK-----CELPRPPSCSLHP----EMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEG-LNCSFVLEMVNNFRALRSETELLLSGK-MALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEE----SVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JQ65-1", "uniprot_id": "DGKH_DROME", "id": "A8JQ65-1", "name": "Diacylglycerol kinase eta", "aln": "------------------------------------MAHLKLDTLHVQRSPRGSRRSSPSSGR--SSACSSGSISPVPIIPIISISHDGDESESESEIETEPARLFQRRMSTKCTNNLAAIIKEGFLLKHTWSFQRWRRRYFRLKRNMLFYAKDEKCDVFDDIDLSDLCYFECGIKNVNHSFQIITPTRSLVLCAESRREMEDWLGSLKTATAPQRPRGDSFLIEQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKDIIEQADGIIMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAVACPIGPAKLSVVPPTSVHSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAIP-----VPKTPKMSISTEQEAMLTGMVTSANHHLRFIVETNDTQTLIRSTRNLCDTVDDLVCRIS-------EHHKDDEQLAVKCDILRQKLNMLLDALQEEEIGAHSGDDLIATIRSLIARSIPVTPGSNAYLLNPNISIEKTEKDQINTKERRNSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKLPTASGESTPCTSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVEVIQEIEEGANGETVYRKSRMSLTGGANIDDAGNRLSPCSDAGENTPTERKVDFLRVPIHTGEPIVDPLCDYRPHEVFERTYYMTREMDKGKEKDKEKDKPVEIDKEKDTCVEKEGSMPAEKLVHTCNLQVPGVVVTPNPQNVYSSASITIIDTDAQTTTEQSSSDDLGGEASDVLSAISNEECSVASEIFDKQDAGQTVGDIIQNMDASNFTHIDSPETSDETEAMPGESIMDDISSVLGHDITYALQDNTLTDDTTTLCSEHAGPPKPPRKKSLSALSRTQAHPRRRNSSPPRMARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLEQHRGGDNDSDYPEHEQTPTNKGANLLATTSEDELSTQTAIKIEIQDIDATVRNLNSSMKPNTILTTSTSPTKKSGHGQDVKRITFDESCKKESFDDVNPNYPQISVVVRPPTPLRGDCIKPTVSLLPVSSGGAMTVSMTCSGMLGVRAMNASEIRRHSSHAPGLAVREFDKDKDRRHSGFNPNQLTLDPEHARFLSSSPAASRRISCGSLFKPNEALPNLQTLKGSKSSLFMGSTLFGFDHLASAEKDKEEKSGKDKEKTPTDETNRKLPIINPLVRLPNWPNLANGGGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLELSLKSWQEKQRQHSISIQRDASSTASEHANSTDEVISERECYVLLNFIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLR-AYFNVLAPNEESDGRRKSRPFWVRLRSGSTAG-QQAFKPPLTNTREAANNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.::*: .* * * . . : :.*:**.* *. ..: : *::**. . :*:***:* *:. **** :****:*: . *:*** *. :**::**:* . *.. ****:** :*** *.*:***:.*:*****:.:***. :: . .: ::: :*. *:*** ************:.*************** *.*****.:: *********:******: *** *****:*******: * **.*****************:* **.:*: .: **:* .*:**:***:::**.:*. *..:.* . ***********************************:. ** ******::*: ******.************* :*:*****:.*:****************:*****:***** : * **********:*.:* :* . * . * .:* : :* *. ** *: ::: ..:* *:: **:**.*:*.*:. * ::.* :* **.:*::**: **.:*::*. .: * :.. . **.. **. .* : *:: . :*. :* * ****:*:** :::**:* :*** :*: *:.: .*: :.:.::* *: * . .*. :.. .:: : : :: ::.. :* *. : ** . :..*.**. . :* * :** * ** **..**: ** ***.: : . * * ************:********:***:*********::* *******:*:**::* :****:* *****: ****.****.:*****: *******.:*:** * .*****::*********:***.**:*.*********::*:*.***** :*:*******:**** ***:****.* * *:*::* :****::**: : ..: * *. *::**.*. : :* :*.. *:: :: : ** ::::* ... :*:::: :: : : ** : ::*:::. * * .:: ** .: :* * : :*.:** :*: :*:: : : . . : . * ::**. .** : . :: * : ..: *..:**.:*** :.*.** * * ::****.*** * *********.****:**** .**:**.. ", "identical_positions": 579, "similar_positions": 355, "identity": "29.65%" }, { "cls_id": "homologset.agr.MGI:2138346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C341-1", "uniprot_id": "SUCO_MOUSE", "id": "Q8C341-1", "name": "SUN domain-containing ossification factor", "aln": "--MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTS-YYSQDDNCAIGSEDTQFQKKNEREEPSN---------------AELSGKSNSYLTISPEGNKIKDDYTVDVQDLET-----TKLSLPVVEALPTVDLHEE--SSSVVVGSETIENSSSSSTSERTPVSELDEVEKSGTLSIAKPGE--VEQPEADCDAGEAPDADAPVEQ---------PAFVSPPESLVG--------QHIENVSSSHGKE-----------KVTKSEFESKVSVSEQDG-----GDPKSALNTSDTLKNESSDYTKPGETD--PTSVTS--------PKDP-----EDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKN-------------RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCST-KIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNK--WIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVN-IAANILGAKT---------EDLTEGNKSISENATATTEPKMTESTRVSTPVPSPEYVIKEVHTHD----------------REPSTSDPPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSSWFESETHILCSELTSICCISSFSEYIYKWCSVRIALYRQR------------SRT-VSKGKDF-VPPQPSLLLPVESVEVSVPQPPSGDVDSENMEREAETVDLDDLSS-VHQGHLINHTVDTIELEPSYPQTLSQSLLLDVTPEMNSLSKVEGSESVKSEGGYIPSQLMTQESSVEFDDKTEKKTESFSSAEKLSVIYETSKVNEVMDNTVKEDILSTEVVTKFPET-----VVPPPMNTATVPEGESVETKPSIADTLKHTVTPVMDP-SLPEVKEDEQSPEDALLRGLQRTATDFYAELQNSTDLGY----GNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRTTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVD--------------------------------PNDLYIVEPLKFSPEKKKKRCKYKT-EKIETIKPADPLHPIANGDIKGRK-PFTNQRDFSNMGEVYHSSYKGPPSEGSSE--TSSQSEESYFCGISAC---TSLCNGQTQ----KTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q710E6-1", "uniprot_id": "SUCO_RAT", "id": "Q710E6-1", "name": "SUN domain-containing ossification factor", "aln": "--MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTS-YYSQDDNCAVGSEDIQFQKKNEREEPSN---------------AKVSEKSNSYLTISPEENKLKDDYTVDECKIWKQ----SKLSLPVVEALPTVDSHEE--SSSVVVGSENIENSSSSSTSETSPISKLDEIENSGTLSVAKPGD--TEQPEADCDAGEAADADASVEQ---------PAFVSAPESLVG--------QHIENVSSSHGKE-----------KVTKSEFESKVSVSEQDG-----GDPKSALNASDTLKNESSDYTKPRETD--PTSVTS--------PKDP-----EDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKN-------------RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCST-KIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNK--WIKLGTFHGRDERTVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVN-IAANILGAKT---------EDLTEGDKSISENATATTEPKMPESTGVSTPVPSPEYIIKEVHTHD----------------TEPPTSDPPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSSWFESETQILCSELTSICCISSFSEYLYKWCSVRIALYRQH------------SRT-VSKGKD--VSPQPSLLPPVDSVEVSVLQPPSGNVDKEDMERELETVALDDLSS-VHQAHVRNHTVDTVELEPSYPQTLSQSLPLDVTPEMDSLSTVEGSESVKSEGGHKPSQVMPQESSVEFDDETEKKPESFSSVAKLSVIYETSKVNEVMDGPVKEDIVSTHVVTKFPETKFPETVAPPPINTAAVPESEGMETKPSLADTLKHVVTPVTDP-SLPEVKEDEQSPDDALLRGLQRTATDFYAELQNSTDLGY----GNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQIVSNLSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRNTSQFDGDYTSKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKE-D--------------------------------PNDLYIVEPLKFSPEKKKKRCKYKT-EKIETIKPADPLHPIANGDIKGRK-PFTNQRDFSSMGEVYHSSYKGPPSEGSSE--TSSQSEESYFCGISAC---TSLCNGQTQ----KTKLR-RGLKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBS9-1", "uniprot_id": "SUCO_HUMAN", "id": "Q9UBS9-1", "name": "SUN domain-containing ossification factor", "aln": "--MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKDEREGPIN---------------AESLGKSGSNLPISPKEHKLKDDSIVDVQNTES-----KKLSPPVVETLPTVDLHEE--SSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE--TEQSETDCDVGEALDASAPIEQ---------PSFVSPPDSLVG--------QHIENVSSSHGKG-----------KITKSEFESKVSASEQGG-----GDPKSALNASDNLKNESSDYTKPGDID--PTSVAS--------PKDP-----EDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKN-------------RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCST-KIWFVIELCEPIQVKQLDIANYELFSSTPKDFLVSISDRYPTNK--WIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYPLDYNTGEDKSSKNLLGSATNAILNMVN-IAANILGAKT---------EDLTEGNKSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHD----------------MEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQR------------SRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSET------IVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGY----ANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVD--------------------------------PNDLYIVEPLKFSPEKKKKRCKYKI-EKIETIKPEEPLHPIANGDIKGRK-PFTNQRDFSNMGEVYHSSYKGPPSEGSSE--TSSQSEESYFCGISAC---TSLCNGQSQ----KTKTEKRALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IAV9-1", "uniprot_id": "A0A0R4IAV9_DANRE", "id": "A0A0R4IAV9-1", "name": "SUN domain-containing ossification factor", "aln": "--MKKLR---VLFLCSVLALLCWHSCHDVYCSEEVSSGPGLPAQDDGSYTMQEPGAGEKVEEERATHTQSS-------YDVGLETERAALKETSLHSQETPHEEKHKQTVNLEEVLEEPQIQHDSALPELEQQQQQEQHPEGQSSQHPDQQDSAQPPTFAQPETAPPLSQPDPEVPQATATEDQAAQPSTDETPPHPDPHAEEDASAPADELQNSPESTSPTSVTSSESLSSGLDVPRPDAAVENSSASQCEVGSVPPFSQQLGTTLTSVVEEQVETQAENQSTVLEQSTETSTDPADSLDPSELDLTETGQTDRIPPPTESQQVADHEGATDPPVPSKEDIPTFDEWKKKVMEVEEKKSQSLHTSSNGSPHPVKKVQKNF------------KNNYASVECGAKILSANNEAKSTSAILMENMDLYMLNPCST-KIWFVIELCEPIQVKQLDIANFELFSSTPRDFLVSISDRYPTNK--WIKLGTFHARDERTVQSFPLDEQLYAKYVKMFIRYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYDEIADSQYTSERAEYLDEDYDYPPGYLPSEDKASKNLLGSATNAILNMVNNIAANVLGGKPE-------LEDGAELEGNVSS-GTENVTQASTETTLTPDPTPTEQPHTLDVLELDPTFVKEDMEAPIPEAPSQAPTVAPAEESRIVILIEEDEESTQPTVTLLEEEGEEERRLEELWESESTTYCGHLSTLSCLASLHEHFYCYCSAALALQRQRKDRRHKAQHTQAHTKTQTTSQQTLTDPTPSQEPPAPSEKLSEAERPS-QTQSERISPTETAAAPSESSNWESSSTELELPPETILLEPSRTSTLPP-HSFSETPTQNIPESLPTGEPVDQRPQYLVDIPETHAPGSVCSSTSSVPSPSAVSSTPLSSTTEPHSL-ETDPPKLELPVPTKEQTAQPLPTHTRPAEIPPPTEIPILIPEASENGKVSLVEDQHHN--AVVSQPELSEAP-HEDTVDDILLP--HRTAGEFYAEQQQTAEMGHSNGNGNGNQVHGSNQKESVFMRLNNRIKALEMNMSLSSRYLEELSQRYRKQMEEMQRAFNKTIIKLQNTSRIAEEQDQKQTESIQMLQSQLENATRIMLNLSATVAQLQREVSDRQIYLVLSLILCLMLGLLLCTQCCRSSTNHN--TSPTIPMSNNYPSPKRCFSSYDDMSLKRRVSCPLVRSKSFQLPTSEVG--------------------------------PDDLYIVEPLRFSPEKKKKRCKTKAGERVETLR-ASATAPNGLLKLNGESSPPLQFLPSTCNGYTSTCSSRDCASEGSSESSVSTLSEESFGSAPSVNGHELVLYNGEPP----PACPPAKSRTEKKRRRSRQG--EQDSMLSASLPLPALEELIKGKTELGVASFGRTAVTGRV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12232-1", "uniprot_id": "SLP1_YEAST", "id": "Q12232-1", "name": "Uncharacterized protein SLP1", "aln": "----------MANRLLIYGLILWVSIIGSFALDRNKTAQNAKIGLHDTTVITTGSTTNVQKEHSSPLSTG---------------------------SLRTHDFRQASKVDIR---------------------QADIREN--------GERKEQDALTQPATPRNPGDSSNSFLSFDEWKKVKSKEHSSGPERHLSRVREPVDPSCYKEK-----------------------------------------------------ECIGEELEIDLGFLTNKN-------------------------------------------------------------EWSEREENQKGFNEEKD-------------IEKVYKK-------------KFNYASLDCAATIVKSNPEAIGATSTLIESKDKYLLNPCSAPQQFIVIELCEDILVEEIEIANYEFFSSTFKRFRVSVSDRIPMVKNEWTILGEFEARNSRELQKFQIHN------PQIWASYLKIEILSHYEDEFYCPISLIKVYGKSMMDEFK-IDQLKAQEDKEQSIGTNNINNLNEQNIQDRCNNIETRLETPNTSNLSD-----LAGALSCTSKLI-P------------------------------------------------------------------------------------------------------LKFDEFFKVLNASFCPSKQMISSSSSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVPVIPE------------------------------------------------------------------------------------------------------------------------------ESIFKNIMKRLSQLETNSSLTVSYIEEQSKLLSKSFEQLEMAH-----------------EAKFSHLVTIFNETMMSNLDLLNNFANQLKDQSLRILEEQ---------------------KLENDKFTNRHLLHLERLEKEVSFQRRIVYASFFAFVGLISYLLITR---------------------------------------------ELYFED-----FEESKNGAIEKADIVQQAIR-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VIK7-1", "uniprot_id": "Q9VIK7_DROME", "id": "Q9VIK7-1", "name": "SUN domain-containing protein", "aln": "MHMRLHLVRFMFINLLLSCCFWLYDNVAAADSQIPSRAGDSAKDAARKTHIEPEEPAAPPRPEPPPPPLHNGAGVLLPSAQEGVPIVATSSSSSFAEVPQTGNRPISGDTSVPVKELPALSDQQRTKSHSEYISEIDLAADVGGASSSTAQVPNNQLNYNKRSSAGKVHRFSESQQLDQPKQLEQEEPATGQPKAPELQEPPQLPQAEESFPEIITELPAVTITELPLDRVMNRLDSVILDGSPATAGNHSDEEQHQQQQQPHEDQPMQVSEADEEVPQKDEQMPKINDPGGGIQVEGMVTPEAATVGETQESSEELQPGSAAFNGTEGTANLTNANEEVPMPVFSEWAQKQMEAEASREQAMELEQQVVNKSAQRKNNTGSSSGKPPTLKLRSKNYASPDCGAKIIAHNSESKHTEAVLTQSTDEYMLSTCES-RIWFVVELCEAIQAQKVDVANYELFSSSPKNFTVAVSKRFPTRD--WSNVGRFAAEDKRTIQTFELHP-------HLFGKFVRVDITSHYANEHFCPLSLFRVFGTSEYEAFETEIRPSD-----DLDDFYDDYGAQEQKAAVGSGGNIFQSASDAVMQMVKKAAEVLVKPTKALKWSEESVLCQTPAFEAFSCINCNTTLVERINSLLSCQFQQLQALLSLSHLRSDLLNSRVCQEEFGISLTGSEFASKMGKEQSYFLSMLPAEHVGAMCKLIQAEQNVTDHNHTKAPSLKQHVSSPEPVQDNATATGVRQDCENSKTPTKEPLTPSLEVVVPEVSQEVPSMEDQSSTSSETVSTTNSTPADVNIFNMPSEPEEVVVKVQLPPEPTLPTTLQPSDVESFTDAPSTNALPGSSEAVANGDLGMEEGNPANWDGIDNLLTTTVASITAGGGAAAAAAAVVNGNANIGGAGIVGAGGPASLSSVNMQQKLTNGAQSESVFIRLSNRIKALERNMSLSGQYLEELSRRYKKQVEELQQTLTQQTLTVRQLEDQSRRYVEQEQLYQQHSAELAGEVRALSYQVQACILVIIIVGTCIFLMLVLG--TVYYRKLRRQQQQLLKKDQAGHPPVAAKPKLDRRKSYEQTPNQSTPKQRRPSEEAMLILKECGDSNMQELDPPSRQRKISVCYGSNNNIAANMAIANTNGGASVRNSLHRRKGAKHSWHNSLDTTETSCG--EQTDKFFDVDTLKSIKQSCGKPGKKKSLQQLKPLGLKRQESAPATYTPDLQAEEPATQSDFDESLMLDDDDLANFIPTSDLAYNEFMPEGPSGYQIVDTVDGKPGKEPGTKKSRRLSSPAFFKSPFSKSKNKGYSFNGVKNSHAVHEPTSWEWYRLKRSEKHQQQQQAKLVSKSLPSASLDSSSLSEVNFPLSSSTATTQNSFRILGEAILSSGEGRITPNGNGNAMSGGLASSSSGSGSGGSTTSSTTKKKQRALNNLFRKAFDF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . : . . . .. : : . : . : : ... . . * . : :.* :: : .:. :: :. **** :*.*.*: * *: : : * :. * *:*..*.: : ::*:**** * .::.::**:*:***: : * *::*.* * . * :* * ..:.* :*.* :. ::: :::::: **: .*.:**:**::*:*.* : :. . : . .. : :: . : . . . . :: : :.:: . : : .* * : . :. . : : . : . ..: . : . :: : . : : * : : :. : :: ", "identical_positions": 52, "similar_positions": 154, "identity": "3.62%" }, { "cls_id": "homologset.agr.MGI:2138351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUU3-1", "uniprot_id": "A0ABK0LUU3_RAT", "id": "A0ABK0LUU3-1", "name": "Sushi domain-containing protein 4", "aln": "MYHGMNPSNGDGFLEQQLQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLNVCADPGVPENGFRTPSGGVFFESSVARFHCQDGFKLKGSSKRLCVKRLNGTLGWIPSDKPLCIQEDCRIPRIEDAEIHNKTYRHGDKLIINCHEGFKIRYPDLYNMVSLCRDDGTWDNLPICQGCLRPLASSNGYVNISEFQTSFPVGTVIAYRCFPGFKLEGSEYLECLHNLIWSSSPPRCLALEAQVCPLPPMVSHGDFICHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPTYDEAVNGSSSALGPGYLASVGQGCPLPVDDQSPPAYPG-SGDTDTGP---GESETCDSTSGSSEMLQSLYSPPMCQGGSRPAPDTPDTISSTAGEVASTSPGIDIADEIPLMEEDP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH32-1", "uniprot_id": "SUSD4_MOUSE", "id": "Q8BH32-1", "name": "Sushi domain-containing protein 4", "aln": "MYHGMNPSNGDGFLEQQLQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLNVCADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKHFNGTLGWVPSDKPVCIQEDCRIPQIEDAEIRNKTYRHGEKLVIDCHEGFKIRYPDLYNLVSLCRDDGTWDNLPICQGCLRPLASSNGYVNISEFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRCLALE--VCPLPPMVSHGDFICHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPTYDEAVNGSSSALGPGYPASVGQGCPLPVDDQSPPAYPG-SGDTDTGP---GESETCDSTSGSSEMLQSLYSPPMCQGGSRPAPDTPDTISSTAGEVASTSPGIDIADEIPLMEEDP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VX71-1", "uniprot_id": "SUSD4_HUMAN", "id": "Q5VX71-1", "name": "Sushi domain-containing protein 4", "aln": "MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLQVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCRIPQIEDAEIHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWNNLPICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALE--VCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPSYDEAVSGGLSALGPGYMASVGQGCPLPVDDQSPPAYPG-SGDTDTGP---GESETCDSVSGSSELLQSLYSPPRCQESTHPASDNPDIIASTAEEVASTSPGIDIADEIPLMEEDP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEC4-1", "uniprot_id": "SUSD4_DANRE", "id": "E7FEC4-1", "name": "Sushi domain-containing protein 4", "aln": "MFHHADKGG------KKSAFGHPVCGQIILSIILLRPPLLVTAFPVNT---VEEQICKDPGFPEHGIRTPSIGKFFENSVARFSCADGFSLKGPAKIICTRFYNGSLGWKPSLKPVCLSEDCLPPFIEDADVTNRTYRPGDSLIISCHEGFQIRYPDTETMESVCQADGTWDNQPTCQGCLRPLIPPHSYMNISETKFSVPVGTVVHYQCFPGYKLEGPELLECMYNLIWSDTPPRCLDVE--ACSLPPMIEHGDYTCHPHPCDRYIHGTVVEYYCYPGYSLANDYKYITCQYGQWFPQMQLYCVKDETTWPGFQDSLLTTWKVVACTATSVLLALLLVITAKMFHYKCKSQQSPSDEP-DESRDPNILVVDGVAVPLPSYEEAISGNYCQP-PNDLPPDGLESAQHSEEQNPPSYPGHTGSQNSVPLDTGDVENCDSLSDTSECLQGLQ-PSSSHPGGLNMSEKTNAITS-MEETASTSPSIDIADEIPLVEDGEEDC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* : .. :: :* . * :*::** * . . * : ::* ***.**:*:**** * ***.**:** * *** ***.:* :* : **:*** ** :.:*:.*** * ****:: *:*** *:.*:* *****:***** .: *:*: ****:* * ******** ..:.*:**** : *.*****: *:****:**:*. ***: *****.:***** :* .*.****:.***: ***:**:** ******:** *****:.**********:***. *:**:*.* ***. :::******:** *******.***** *:**: * *:: .* . * ..* **:::*****.* **:*:**:.*. . *. .. * .. ::*.**:*** :*. :: * *: *.*** *.:** **.* *. .: . .:..: *:* *.*****.*********:*:. ", "identical_positions": 250, "similar_positions": 131, "identity": "50.1%" }, { "cls_id": "homologset.agr.MGI:2138365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L348-1", "uniprot_id": "A0ABK0L348_RAT", "id": "A0ABK0L348-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MRDDSGPPLEEDKARPPRALPPVPSAIQ---------------------DEIPLSHPKKKK------------------------SRTKSTPAPASSEG------LAEPVVNRRAEGSEP----------------PAAELKEYPEAPVQRKQKKIRPPPELETSFT---------EK-PSSPSLLRNENGMDVEPREEVVIPKPRRKAKKMQPAEPQYASELGVE------DEDVITDEQSTLEH--HSRFTAPTGVSQPVGKIFVEKSRRFQAADRSELIKTTENVDVS----------------------------------------------------------------------MDMKPSWTTRDVALSVHRAFRMIGLFSHGFLAGCAVWNIVVIC--------------VLAGDQFSNVSN-----------------------------------LLQQYKPLAYPFQSLLYLLLALSTVSAFDRIDFAKTSVAIRNFLALEPTALASFLYFTALTLSLSQQMTSDRIYLYEP-SVNGSLWPAEVEEPVLMPWVIVNLVVALLVGLAWLFLSYRPGMDLSEELMFFSDVDEYP--ERGVKASP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V0J1-1", "uniprot_id": "TM237_MOUSE", "id": "Q3V0J1-1", "name": "Transmembrane protein 237", "aln": "-----------------------------------------------------------------------------------------------------------MRDDSGPPLEEDQARPPRALPPVPSAIQVCSSFVENNSRMDQQDDLVGEDDIPLSHPKKKK------------------------SRTKSSLATASSEG------HAEPVVNRRAEGSEP----------------PAAELKEHPEAPAPRRQKKIRPPPELETSLT---------ER-PSSPSLLRNENGIDAEPREEAVIPKPRRKAKKTQPAEPQYASELGVE------DEDILTDEQSTLEH--HSRFTAPTGVSQPVGKVFVEKSRRFQAADRSELIKTTENIDVS----------------------------------------------------------------------MDVKPSWTTRDVALSVHRAFRMVGLFSHGFLAGCAVWNTVVIY--------------VLAGDQLSNVSN-----------------------------------LLQQYKPLAYPFQSLLYLLLALSTVSAFDRTDFAKISVAIRNFLALEPTALASFLYFTALILSLSQQMTSDRIHLYEP-SVNGSLWAAEAEEPILVPWIIVNLVVALLVGLSWLFLSYRPGMDLSEELMFFSDVDEHP--ETGTKASP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96Q45-1", "uniprot_id": "TM237_HUMAN", "id": "Q96Q45-1", "name": "Transmembrane protein 237", "aln": "-----------------------------------------------------------------------------------------------------------MRTDSGARLEEGHLRPPRALPPVP--SQ---------------------DDIPLSRPKKKK------------------------PRTKNTPASASLEG------LAQTAGRRPSEGNEP----------------STKELKEHPEAPVQRRQKKTRLPLELETSST---------QKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVE------DEDIITDEQTTVEQ--QSVFTAPTGISQPVGKVFVEKSRRFQAADRSELIKTTENIDVS----------------------------------------------------------------------MDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCAVWNIVVIY--------------VLAGDQLSNLSN-----------------------------------LLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAIRNFLALDPTALASFLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIVVNLVVALLVGLSWLFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q930-1", "uniprot_id": "T237A_DANRE", "id": "F1Q930-1", "name": "Transmembrane protein 237A", "aln": "---------------------------------------------------------------------------------------------------------------------------------MCVTSR--------------------ADKMPSVKPKKKK------------------------IKKEINEVEEPEAGPEPAIEMEGLESRRQSESREP----------------LTPEPHDNP--PLKKKKKKKTHTFENEG----------------EQQDHP-NGDVQESPTDGEEVTKKSKK-KRKNKMMENQSHNELGVE------EDDIITDVHAPISQ--RSLFSAPLSHSHPIGKVFVEKNRRFQATD------LSHDHLEEY---------------------------------------------------------------------MEVRPMWNTRDVAMRVHSGFRIIGLFSHGFLAGYAVWNIIVVY--------------VLAGEQMTTLPN-----------------------------------LLQQYHSLAYPAQSLLYLLLAISTVSAFDRVNLAKASMALRGFLTLDPAALASFLYFAALILSLSQQMTSDRIHLYP--TANETLWPPGLEHQILQPWIVVNLVVALLVGLAWVFVATRPDMDYTEEFLMAMEVEEYPRHDDKHELAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q66IE4-1", "uniprot_id": "T237B_DANRE", "id": "Q66IE4-1", "name": "Transmembrane protein 237B", "aln": "--------------------------------------------------------------------------------------------------MDPEAKVSSSRRRDLPPIPQGQRRTPRALPSMPSQDT--------------------AEEMPAPKSRKKK------------------------AKRDAESVDEPDDG---GMEMGGLASRRQSECPEP----------------LTPEPLDNP--PQRRKKKKKAQAIDAEG----------------DQTDLVSNGDTLDQNTD-EEVTRKPKKRKVKPKVTETQSNNELDVE------DDDVITDPQSPIPQ--HSLFSAPQGPSQPVGKVFVEKSRRFQAADRVEQWKPSGPIEQSI---------------------------------------------------------------------MDIRSMWTTRDVSMRVHSGFRVIGLFSHGFLAGYAVWNIIVVY--------------VLAGDQMSSLSN-----------------------------------LLQQFHTLAYPAQSLLYLLLALSTVSAFDRVNLAKAPAAMRSLLRLSPVALASVFYFSALVLSLSQQMTSDRINLYKYSSYNTTLWPPGSESSILYPWITVNLVVSLLVGLAWILMSTSPDIDNTEAFLMSMEM-EYPNSEEKGNVTA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW76-1", "uniprot_id": "Q9VW76_DROME", "id": "Q9VW76-1", "name": "", "aln": "MEAKVHRQHQRHRRTEARQRRLEREAVATGAAAPTPTTPERAEALDCATALNEGVVSADPGGSGGTPSSAGRISAQSSADSIELVGSPSQTSQQTVVLVNGHAPPGQEEGEEESPLGAGNTRDSPPPPKQSDGSR--------NSSGDAMSLRETLQQLPATHHHRSRRTHSPADPDASFHRGILGYMDRELKQSSPTPSAPAGTGNGTGNGTSTGASRKQQSLSDPQASPAQRSLRSRSSFDKSPRRKRSKSESRRRRERKLIAAGEMEVRQANETLMRYLKQCSDMHDASLSGELEIDQSLEERRVHRKTKSQRDKRGQLISKLYSAGGISSILKELADDIAPADGEEIYNPFTPVVSPTDDAPAHIDKMFLQTSSGYRPVEHSYYKRSFLGAAVRGSAGISASGGGGGCAGGGGGRLDGISAAELGGAGRLFRSSGSHAHGGDRMGGNGSGRGSYGDTRCLLDADFNRNGITSNIQLACVVQRIWLLISNICHGLLAGLALAHLLFVLSSHPMDWAKVINGMSLAGETVSSTAQPPAASTPSAIDIDSGDRGTESGESSSPSAAASGLALISDYAGFAEIYLNTFYCLAIICLVSVFDRMDICRWSFSNASELISFRWLIITMIYVATIILAICSDSIDEKLYLFNNNANITLTQQEMLSNSVQSVWSSLSVTRSIAAISGWIMIGLTPQEDMLYEHLVDLTKYQLTNN--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* : ::.: : . . * .: . :* : . . ::::* . : * . : . * *.: * : . .:. :*: . : : . .:.. . . :.*:*::.. ::..: :: . .. ::: *: : ::. :.**:*** *: : :.: ***: .:. .: *:.:: :* . :* * :. :*.*** ::.: . : . * : :.:*.::: *::..: .::: *: : . : * :.:. :: . .*:::. * * :. : . ", "identical_positions": 37, "similar_positions": 140, "identity": "5.14%" }, { "cls_id": "homologset.agr.MGI:2138391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z2X4-1", "uniprot_id": "PCLI1_HUMAN", "id": "Q7Z2X4-1", "name": "PTB-containing, cubilin and LRP1-interacting protein", "aln": "MFSLPLSLPLCEDTAFLPSKCCSSHKTIKQARTLIMIFLASGTHFQTMLKSKLNVLTLKKEPLPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYLGKVSTTGMQFLSGCTEKPVIELW--KKHTLARED-VFPANALLEIRPFQVWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVSQELES-DDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UBG2-1", "uniprot_id": "PCLI1_MOUSE", "id": "Q3UBG2-1", "name": "PTB-containing, cubilin and LRP1-interacting protein", "aln": "-----MWQPATER----------------------------LQHFQTMLKSKLNVLTLKKEPIPAVLFHEPEAIELCTTTPLMKARTHSGCKVTYLGKVSTTGMQFLSGCTEKPVIELW--KKHTLARED-VFPANALLEIRPFQVWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVQCESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRSSSSEEASQELES-DDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB40E7W4-1", "uniprot_id": "A0AB40E7W4_DANRE", "id": "A0AB40E7W4-1", "name": "PTB-containing, cubilin and LRP1-interacting protein", "aln": "-----MWQPASER----------------------------LQHLQSMLKTKLNVLTLRKDPLPTVIFHEPEAIELCSTTPNAKNRTHTGYKVTYLGKVTISGTHFLSGCTESAVVGLWDTKQTSVTHDDSITSSNAILEIRPFQVRMHHLDGRGEATVAMDTFQVARIAYCTADHDISPNVFAWIYRQINDDLTFQMDCHAVECESKLEAKKLAHSMMEAFKKTFHSMRSDGRIHKSGSSDEFPEEPSTPDDG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *:*:***:*******:*:*:*:*:**********:*** * ***:* ********: :* :*******..*: ** *: :::::* : .:**:******** :**** :***** ****************::***:***:**:*****::*******:************:*****:******:****** ..**:* .:* .: ***", "identical_positions": 148, "similar_positions": 47, "identity": "58.27%" }, { "cls_id": "homologset.agr.MGI:2138446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FE2-1", "uniprot_id": "ATG9A_MOUSE", "id": "Q68FE2-1", "name": "Autophagy-related protein 9A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQFDTEYQRLEASYS-----------------------------------------------------------------DSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIH------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDED------VLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAED------------GKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAE--PERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRGPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FWU3-1", "uniprot_id": "ATG9A_RAT", "id": "Q5FWU3-1", "name": "Autophagy-related protein 9A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQFDTEYQRLEASYS-----------------------------------------------------------------DSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIH------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDED------VLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAED------------GKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPPLSRDLQGSRHRADVASALRSFSPLQPGQAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAE--PERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRAPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z3C6-1", "uniprot_id": "ATG9A_HUMAN", "id": "Q7Z3C6-1", "name": "Autophagy-related protein 9A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQFDTEYQRLEASYS-----------------------------------------------------------------DSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIH------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEAVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDED------VLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSAGQTEASVYQQAED------------GKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAASLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPPLPRDLQGSRHRAEVASALRSFSPLQPGQAPTGRAHSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQAQAE--PERHVWHRRESDESGESAPDEGGEGARAPQSIPRSASYPCAAPRPGAPETTALHGGFQRRYGGITDPGTVPRVPSHFSRLPLGGWAEDGQSASRHPEPVPEEGSEDELPPQVHKV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KF86-1", "uniprot_id": "A0A0B4KF86_DROME", "id": "A0A0B4KF86-1", "name": "Autophagy-related protein 9", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPHINYRSLAEEAASPFLEHHPSTGQGPSKTQDAKANAAAAHLDPLGEHGLEQPLDEH--------------DTEHEGEDTPRNSGVMIHMVPETGRARWNHIEDLDSFFSRMYQYQQKHGFTVIVVDEMLQVLEFGFVVWLLAFVMHCVRFDVLFG----DTPPGGLNPNKTTLSDVMYPTGECLANFT--WVTYLVVFIAAIYLGIRLLKMVYHITQYADIKRFYNSALHIEDSDLDNFTWHEVQQRIRRVQAEQHMCID------KESLTELDIYHRVLRFKNYLVALMNKQLLPVRFHIPLYGEVVSLSRGMLFNIDFILFRGPGSPFQNNWQLRDEFAVRSNQTELAQRLSKLILGVALLNLVLAPVIFVWQLIYFSFSYANILRKEPGALGLRTWSNYGRLYLRHFNELDHELDARLNRAYDYADRYLNSFSSPLAAVIAKNLLFISGGLLLLILALGIYEEH------VFQVEHLLAILAGLGAIGVVCRTLIPDENLVWCPEQLMTAILAHVHYLPSEWRQQAHTTKVRQEFSNFFQFKAGYLLSEIFSPFVTPFVLIFVFRPKAIELVRFFRTFTVSVRGVGNVCSFAQMDVRKHGNPDWQLTSELEEMTRATAQQPQQEPQQQSLAGGKTEMSLLRFTLNNPEWQMPKEAKQFLRGVREHAVG---ELVQAKTSMVQENPLTNSLISFGTMGADYCSIANSVLTA-----------QVTPQQLEISQSLR------PGLGP-----------------VSGGFPVAASDFRQMLQQNLSASVGPLDSMRRLRLSRAEGRLEGPTDTLLYGLCGVDPRVGSTPLNVG-----VADMCLSALYLHELNQQKR----------QARQSRIDEAEDERPGTSHWPPRPPAAPSADTGFGSRHTVITSKAAESTPLLGSIRSXQRPEWI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12142-1", "uniprot_id": "ATG9_YEAST", "id": "Q12142-1", "name": "Autophagy-related protein 9", "aln": "MERDEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLPDIERGSSLLHSTNDSREDVDENDLRVPESDQGTSTEEEDEVDEEQVQAYAPQISDGLDGDHQLNSVTSKENVLETEKSNLERLVEGSTDDSVPKVGQLSSEEEEDNEFINNDGFDDDTPLFQKSKIHEFSSKKSNTIEDGKRPLFFRHILQNNRPQRDTQKLFTSSNAIHHDKDKSANNGPRNINGNQKHGTKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVLNNTPEDRINTLSVKERALWKWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLLFVVFVSTYMGHCVDYSKLPT----------SHRVSDIIIDKCYSNSIT-------GFTKFFLWMFYFFVILKIVQLYFDVQKLSELQNFYKYLLNISDDELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKNRIDAHDVANRIMRRENYLIALYNSDILNLSLPIPLF-RTNVLTKTLEWNINLCVMG---FVFNESGFIKQSILKPSQREFTREELQKRFMLAGFLNIILAPFLVTYFVLLYFFRYFNEYKTSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKYVDQFPKEKTNLFLKFVSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRNTITQEYHVFDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPFVLWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMKNIDGEDTHSMDE-DSLTKKIAVN------------GSHTLNSKRRSKFTAEDHSDKD--------------------LANNKMLQSYVYFMDDYSNSENLTGKYQLP-----------------------------------------------------------AKKGYPNNEGDSFLNNKYSWRKQFQPGQKPELFRIGKHALGPGHNISPAIYSTRNPGKNWDNNNNGDDIKNGTNNATAKNDDNNGNND-----------HEYVLTESFLDSGAFPNHDVIDHNKMLNSNYNGNGILNKGGVLGLVKEYYKKSDVGR----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * . :.. . * * . * ::*:** *:. :*: :** ::: ::::: : *** . ::: ** :. * . . : * . .: : .: ::::: :.: ::: ** *.* . * .*::* :: : :: : . *. : *: :*::* :**::** *..:* : : :* .. ::: : :*::: :: * :. :: . .:: :.*.: :: .: *::*.*.:. : :: * * : : .**::* * :: .. :*.:*** * :. *:. . *.:*:: * . :: * *:.*.:: :: * ::: . : . :: :: **. *.*. *.:: *: **: : : : **:*..*. . * : : **.:::: : :* *: * ::**::* * : . * .:: *** : * *:* .*.:* ::::: . : .: : . * : *. :. : : .. : :: *: :: . . * :. .. * . .: . . . :: : . :: . . . . . : . . . : . : . ", "identical_positions": 97, "similar_positions": 253, "identity": "8.58%" }, { "cls_id": "homologset.agr.MGI:2138453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L854-1", "uniprot_id": "A0ABK0L854_RAT", "id": "A0ABK0L854-1", "name": "Protein maelstrom homolog", "aln": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRAAQGKDSGPSEKQGLVMAHWLKARATLPEDPVSSQCTYMKLVSTPLRRPGMLVPKPSVSPPDMSNLSIKSDQALLGGVFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISNFEFG-HDQATVLQNLYKFIHPNPGN--WPPIYCKSDDRARVNWCLKRMERASEIR---QDLELLTVEDLVVGIYQQKFLKEPS------KTWVRSLLDVAMWDYSSNTRCKWHEEND-ILFCALAVCKKIAYCISNSLATLFGIQLT-GAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNSSTGYYPSGVKISGSNSSVRGRGITRLLESISNSSNNIHRFSNCEASLS-----------PYMPQKDGYKPFSSFS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVN9-1", "uniprot_id": "MAEL_MOUSE", "id": "Q8BVN9-1", "name": "Protein maelstrom homolog", "aln": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRAAQGKDSGPSEKQ--------------------------KLVSTPLRRPGMLVPKPSISPPDMSNLSIKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFIHPGEIPRGFRFHCQAASDSSHKIPISNFEFG-HDQATVLQNLYKFIHPNPGN--WPPIYCKSDDRARVNWCLKRMERASEIR---QDLELLTVEDLVVGIYQQKFLKEPS------KTWVRSLLDVAMWDYSSNTRCKWHEEND-ILFCALAVCKKIAYCISNSLATLFGIQLT-GAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNTSTGYYPSGVKISGPHSSVRGRGITRLLESISNSSNNIHRFSSCETSLS-----------PYTPQKDGYKPFSSFS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JY0-1", "uniprot_id": "MAEL_HUMAN", "id": "Q96JY0-1", "name": "Protein maelstrom homolog", "aln": "MPNRKASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSSDWALLREEEKEKYAEMAREWRAAQGKDPGPSEKQ--------------------------KPVFTPLRRPGMLVPKQNVSPPDMSALSLKGDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISNFERG-HNQATVLQNLYRFIHPNPGN--WPPIYCKSDDRTRVNWCLKHMAKASEIR---QDLQLLTVEDLVVGIYQQKFLKEPS------KTWIRSLLDVAMWDYSSNTRCKWHEEND-ILFCALAVCKKIAYCISNSLATLFGIQLT-EAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVGSSGFSHFNSSNEEQRSNTPIGDYPSRAKISGQNSSVRGRGITRLLESISNSSSNIHKFSNCDTSLS-----------PYMSQKDGYKSFSSLS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNS0-1", "uniprot_id": "MAEL_DROME", "id": "Q9VNS0-1", "name": "Protein maelstrom", "aln": "MAPKKHSG--FMMFVNEWR--NRNAEGRRMTLAQAVSHCGTIWEKMNTQQRGPYNSGGKDANVAQRAKRESSNGHG-------------------------QVDKAQREATESLMDMKRTIERLVLNAKMSHDLENAKFVFVAFNYFTK----ALTTDVYVPAEFAACEYSLKEGIRSIYSTMIDPGQIIFGQGSDALLHSSTTHDLPLPPNALGEKNMTKLYRNIVDYLSKCQGKGKTLVVFTPAENITMVKSCFRYLECDDDFRDGGEKIQVFDIQYLLFILKKEVMNVADLNDEKINKFATDAFFKKDFFEFTAGIACQYHEDNDRTKYCTQSMVTRWAYTFTDFMCGDLAITVQPGKHIPAQTKPNYLIISSYASSLDHESSFDSFYSLPGSGVKKESQPEACSLSSSRLSVASSSYKPIDHTSFAANLNEVSEFPSLGMRNSSKHHGIAASAQREWNARNLPTHSRLIRKVSDNDFSVNGADGKLKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: * : :**:* *. :*:*:.:*.: * :. ::: * . .:: ..** . .*: : : : . . *: : .:. * :* :* *:: . : ::*.*:.. :***:*** : : ::*.**:* * .. *.::*.:*:. * :: :.: :*: :: *: :: ::: : *: *:: : .::* :.:::: :: *:. : :: : * :::. ::::::. *::**:** :*: :: .: ** ::: :. :.* : *:* * ::. ** . .* :. : * * :. : . . . : . .:..: * * . * :. . :* . . :* . : ** . ", "identical_positions": 67, "similar_positions": 165, "identity": "13.62%" }, { "cls_id": "homologset.agr.MGI:2138477", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9G4-1", "uniprot_id": "D3Z9G4_RAT", "id": "D3Z9G4-1", "name": "", "aln": "------------------------------------------------------------------MSERRSLHETGMSDPHGKAWWNIPDYFHSPLMFYMEEDQEEYIFGPEDEYLRRMEVHSNTLIQLERGFTASGQTRVSVVGPIQARLWVMNMITKVGSQNTFDQTTGKIMLLRIRSQPLSEQDLK----FDPESGSSLWFPD------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7A0-1", "uniprot_id": "KHD1B_MOUSE", "id": "P0C7A0-1", "name": "KH homology domain-containing protein 1B", "aln": "-----------------------------------------------------------------------------MSDLRRKGWWNVPDYFYSPLVFDMEEDQEDYIFGPDDEYLHTLEVHSNTLIQLERWFSPTGQTRVTVVGPLKARLWVMDMIRKVGSKNTLDKIKGKLMLLHIRSHPLTDQDLQ----IHLISGSSCWFPD------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VXA5-1", "uniprot_id": "KHDC1_HUMAN", "id": "Q4VXA5-1", "name": "KH homology domain-containing protein 1", "aln": "MLSAFQRLFRVLFVIETVSEYGVLIFIYGWPFLQTLAMLLIGTVSFHLWIRRNRERNSRSGKTRCRSKRSEQSMDMGTSALSKKPWWTLPQNFHAPMVFHMEEDQEELIFGHGDTYLRCIEVHSHTLIQLESWFTATGQTRVTVVGPHRARQWLLHMFCCVGSQDSYHHARGLEMLERVRSQPLTNDDLVTSISVPPYTGDLSLAPRISGTVCLSVPQPSPYQVIGCSGFHLSSLYP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5JSQ8-1", "uniprot_id": "KHDCL_HUMAN", "id": "Q5JSQ8-1", "name": "KHDC1-like protein", "aln": "-------------------------------------------------------------------------MAVGTSALSKEPWWTLPENFHSPMVFHMEEDQEELIFGLDDTYLRCIELHSHTLIQLERCFTATGQTRVTVVGPPMAKQWLLLMFHCVGSQDSKCHARGLKMLERVRSQPLTNDDLVTSVSLPPYTGD------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : **.:*: *::*::* ******: *** * **: :*:**:****** *:.:*****:**** *: *:: *: ***::: : * ** ::**:**:::** . :*. ", "identical_positions": 54, "similar_positions": 34, "identity": "22.78%" }, { "cls_id": "homologset.agr.MGI:2138563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VI60-1", "uniprot_id": "SULF1_RAT", "id": "Q8VI60-1", "name": "Extracellular sulfatase Sulf-1", "aln": "-MKNS----------CWALLLAVLGAELLGGFCSTMRSQRFRGRVQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFTNAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQALHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNVLQRKRLQTLMSVDDSVERLYNMLVETGELGNTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSIEPGSIVPQIVLNIDLAPTILDIAGLDTPSDVDGKSVLKLLD---------------LEKPGNR------FRTNKKAKIWR-----------DTFLVERGK------------------------------------------------------------FLRKKEESSKNIQQSNHLP------KYERVKELCQQARYQTACEQPGQNWQCIEDTSGKLRIHKCKGPSDLLT-VRQNARNLYSRGLQDKDKECHCRESGYRPSRSQRKKERQFLRNQGTPKYKPRFVHTRQTRSLSVEFEG-----EIYDINLEEEE-LQVLPPRSVAKRHDEGHQGFGGHQAAAGDFRNEMLADSNS--AVGLPTTVRVTHKCFILPNDT-IHCERELYQSARAWKDHKAYIDKEIEVLQDKIKNLREVRGHLKKRKPEECSCGKQ----------------------SYYNKEKGVKRQ---------------------EKLKSHLHPFKEAAAQEVDS-------------KLQLFKEH-RRRKKERKEKKRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHIQLMELRSCQG-------------------------YKQCNPRPKS---------------------LDVGTKEGGNYDPHRGQLWDGWEG-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K007-1", "uniprot_id": "SULF1_MOUSE", "id": "Q8K007-1", "name": "Extracellular sulfatase Sulf-1", "aln": "-MKYS----------LWALLLAVLGTQLLGSLCSTVRSQRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEQGGATFTNAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPIMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNVLQRKRLQTLMSVDDSVERLYNMLVESGELDNTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSIEPGSIVPQIVLNIDLAPTILDIAGLDSPSDVDGKSVLKLLD---------------LEKPGNR------FRTNKKAKIWR-----------DTFLVERGK------------------------------------------------------------FLRKKEESGKNIQQSNHLP------KYERVKELCQQARYQTACEQPGQNWQCIEDTSGKLRIHKCKGPSDLLT-VRQNARNLYSRGLHDKDKECHCRDSGYRSSRSQRKNQRQFLRNKGTPKYKPRFVHTRQTRSLSVEFEG-----EIYDINLEEEE-LQVLPPRSIAKRHDEGHQGFIGHQAAAGDIRNEMLADSNN--AVGLPATVRVTHKCFILPNDT-IHCERELYQSARAWKDHKAYIDKEIEVLQDKIKNLREVRGHLKKRKPEECGCGDQ----------------------SYYNKEKGVKRQ---------------------EKLKSHLHPFKEAAAQEVDS-------------KLQLFKEH-RRRKKERKEKKRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERSILNQLHIQLMELRSCQG-------------------------YKQCNPRPKS---------------------LDIGAKEGGNYDPHRGQLWDGWEG-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWU6-1", "uniprot_id": "SULF1_HUMAN", "id": "Q8IWU6-1", "name": "Extracellular sulfatase Sulf-1", "aln": "-MKYS----------CCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGLDTPPDVDGKSVLKLLD---------------PEKPGNR------FRTNKKAKIWR-----------DTFLVERGK------------------------------------------------------------FLRKKEESSKNIQQSNHLP------KYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLT-VRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQTRSLSVEFEG-----EIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSSN--AVGPPTTVRVTHKCFILPNDS-IHCERELYQSARAWKDHKAYIDKEIEALQDKIKNLREVRGHLKRRKPEECSCSKQ----------------------SYYNKEKGVKKQ---------------------EKLKSHLHPFKEAA-QEVDS-------------KLQLFKENNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQG-------------------------YKQCNPRPKN---------------------LDVGNKDGGSYDLHRGQLWDGWEG-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEX0-1", "uniprot_id": "SULF1_DROME", "id": "Q9VEX0-1", "name": "Extracellular sulfatase SULF-1 homolog", "aln": "MMRHSSLRLIIGGLILLLFVLNVFSKEQGSHSHKRSHSAKRFSRDSNSARERRPNIILILTDDQDVELGSLNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMYVHNHMVFTNNDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNGSYIPPGWREWGGLIMNSKYYNYSINLNGQKIKHGFDYAKDYYPDLIANDSIAFLRSSKQQNQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPNPDKQWILRVTEPMQPVHKRFTNLLMTKRLQTLQSVDVAVERVYNELKELGELDNTYIVYTSDHGYHLGQFGLIKGKSFPFEFDVRVPFLIRGPGIQASKVVNEIVLNVDLAPTFLDMGGVPTPQHMDGRSILPLLLSRNRAVRDNWPDSFLIESSGRRETAEQIAESRARLQIERRNMKLANSSLLEDFLEGAGESTTIVSSSSTAATLMSSTAQQPEDGEEEVETDNEEDDVDGDGAMDSSAAALEEDDLDDAAFEEGDEELDQEFQQNNDLPLAPYITKMMRLNSECSDPALLKNC-LPGQKWKCVNEE-GRWRKHKCKFHLQLEHQLAAMPRKQYQRNCACFTPDGVVYTKIRAPSAGLHRVNKRTHNGPGRRRNKREVFHTELPDEMEELLDLHQVVDQLVDHTHRSKRDLPASSNETIAQVIQQIQSTLEILELKFNEHELHASNSSGNSYERGEKYTKSGGHRCFVDATTAKVNCSNVIYDDEKTWRTSRTQIDMLIKLLKDKIGKLKEMKKQLRESNKQALAAGRRNDNRRRNDQSVLDSGAGPEFNMSYFTEISSTPRSNVVGQTEVFQGYGSASAFDSLEQTQSHRFTPRAECYCEPDVGENHADSKEMAREARRKLKEE-RQRKKERKRIKKARLEKECLSEKMNCFSHDNQHWRTAPLWNDSPFCFCMNANNNTYSCLRTINGTHNFLYCEFTTGLITFYNLTIDRFETINRAAGLTPGERSHMHDALDQLKSCRGRSCSIRRHQNHLEGGSSAPLLPINQVHRNNKRKHSPLAGAVGNYAFVGPRLDMEALPPIKRRKLSKYNRLTGSQQSHMKRRPWKQTPLQQSPRFLRTHSVTPAQA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * ::* *:. : . . :* : .* .:. :: ******:************:.* :* :::..*** * :*:.*******:***:*** ***** *:***:*****.*** **.*::*.**.*:****.:******:************* *** **::***:: ** * **********:.***:*:** ::: **: ::*:::.:*..***********:*:*: *.: * ****::*** **:**:: * ** *:* .***:* ****** *** :***:** * * *** ****:**:*****:*****:****:*::**:****:****.::...:* :****:*****:**:.*: :* .:**:*:* ** *..*.* .:. : :* * : ** *: * . .** .:::**.*.** * *::. *.:. . * ***:*:*::: *: * **** :* : .*: * *. : . .* . :: ::: .. * : * ...**. . .:. :: :: * . ..:. * . ..:*: :: :. : . . . .*.. * * *:**: .. : ::*.. :*:. ::*: :: ** *: *:*** :*:*:: :*:. : : ... : **:.: ... :. *: :** .. : . * * : :**. *:******. :: * :** :.**:***:**:***:** ..** * .:***** ****:* *****:***:**:: ::::. * :: * . : . .::* * :*:**:* :: * * :. : :. ..*: *. . : ", "identical_positions": 355, "similar_positions": 284, "identity": "31.78%" }, { "cls_id": "homologset.agr.MGI:2138584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6Y7W8-1", "uniprot_id": "GGYF2_MOUSE", "id": "Q6Y7W8-1", "name": "GRB10-interacting GYF protein 2", "aln": "MAAETQTLNFGPEWLRALSSGGS--------------------ITSPPLSPALPKYKLADYRYGREEMLALFLKDYKIPFDLLEKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGGTVVGAPRGRSSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEER---GDRRFEKPGRKDVG-----------RPNFEESGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSTGWREHMERRRR---FEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-----KVQKEPIPEEQEMDFRPVEEGE--ERSDSDSSHNEEAKEPDKTNRREGEKTDR-AGAEASEEVPQTSL-SSARPGTPSDHQPQEATQFERKDEPKAEQVEKAEEENRSENSLSAKVPSRGDETVPASQQP--STPLP-PDTASPLLILSPPVPTPSSASRPVETAAVEAPGMS-------------SVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLTSKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWG-RVPFSP-------------------------------GPAPPPHMGELDQERLTRQQE-----------------------------LTAL--YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQALKMRM---------------------------------SDQNIIPSVTRSVSVP----DTGSIWELQPAASQP------------AVWEGGSVWDLPLDTTAPGPSLEQLQQLEKAKAAKLEQERREAEMRAKR-----------------------------------EEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR------------------------------------------RQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELELQRQKDLMRQRQ------------QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTAT--CQSQATLS-LAEIQKLEEERERQLREEQRRQQRELMKALQQ--QQQQQQQQKLSGWGNVSKPAGTTKSLLEIQQEEARQMQK---QQQQQQQQQQQHQQSNRARNSTHSN---------------------LHTSLGNSVWGSINTGPSNQWASELVSSIWSNA-------DTKNSNMGFWDDAVKEVGP-----RNSTNKNKNNASLSKSVGVSNRQNKK-------------VEEEEKLLKLFQG------------VNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYTRAYLGDTSEAKEFAKQFLERRAKQKVNQQRQQQQQQQQQQ-----------------DSVWGMNHSTLHSVFQTNQSN----NQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MKC0-1", "uniprot_id": "A0A096MKC0_RAT", "id": "A0A096MKC0-1", "name": "", "aln": "MAAETQTLNFGPEWLRALSSGGS--------------------ITSPPLSPALPKYKLADYRYGREEMLALFLKDYKIPFDLLEKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGGTVVGAPRGRSSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEER---GDRRFEKPGRKDVG-----------RPNFEESGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSTGWREHMERRRR---FEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-----KVQKEPIPEEQEMDFRPVEEGE--ERSDSDSSHNEEAKEPDKTNRRDGEKTDR-AGTDANEEVPQTSL-SSARPGTPSDHQPQEAAQFERKDEPKAEQMEKAEEESRSENSLPAKIPSRGDETVPASQQP--STQLP-PDTASPLLILSPPLPTPSSASRPVETAAVEAPGMS-------------SVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLTSKLQEHRAKGVSVPLVHEAMQKWYYKDPQGEVQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWG-RVPFSP-------------------------------GPAPPPHMGELDQERLTRQQE-----------------------------LTAL--YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQALKMRM---------------------------------SDQNIIPSVTRSVSVP----DTGSIWELQPAASQP------------AVWEGGSVWDLPLDTTTPGPSLEQLQQLEKAKAAKLEQERREAEMRAKR-----------------------------------EEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR------------------------------------------RQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELELQRQKDLMRQRQ------------QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTT--CQSQATLS-LAEIQKLEEERERQLREEQRRQQRELMKALQQ--QQQQQQQQKLSGWGNVSKPAGTTKSLLEIQQEEARQMQK---QQQQQQQQQQ-HQQSNRARNSTHSN---------------------LHTSIGNSVWGSINTGPPNQWASDLVSSIWSNA-------DTKNSNMGFWDDAVKEVGP-----RNSTNKNKNNASLSKSVGVSNRQNKK-------------VEEEEKLLKLFQG------------VNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYTRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQDSVWGMNHSTLHSVFQTNQSN----NQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Y7W6-1", "uniprot_id": "GGYF2_HUMAN", "id": "Q6Y7W6-1", "name": "GRB10-interacting GYF protein 2", "aln": "MAAETQTLNFGPEWLRALSSGGS--------------------ITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGG-TVVGAPRGRSSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEER---GDRRFEKPGRKDVG-----------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRR---FEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-----KVQKEPIPEEQEMDFRPVDEGE--ECSDSEGSHNEEAKEPDKTNKKEGEKTDR-VGVEASEETPQTSS-SSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQP--LSQIP-SDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMG-------------SVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWG-RVPFSP-------------------------------GPAPPPHMGELDQERLTRQQE-----------------------------LTAL--YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRI---------------------------------SDQNIIPSVTRSVSVP----DTGSIWELQPTASQP------------TVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKR-----------------------------------EEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR------------------------------------------RQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELEVQRQKELMRQRQ------------QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA--CQSQATLS-LAEIQKLEEERERQLREEQRRQQRELMKALQQ--QQQQQQQ-KLSGWGNVSKPSGTTKSLLEIQQEEARQMQK---QQQQQQQHQQ----PNRARNNTHSN---------------------LHTSIGNSVWGSINTGPPNQWASDLVSSIWSNA-------DTKNSNMGFWDDAVKEVGP-----RNSTNKNKNNASLSKSVGVSNRQNKK-------------VEEEEKLLKLFQG------------VNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQ---QDSVWGMNHSTLHSVFQTNQSN----NQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KME6-1", "uniprot_id": "GGYF2_DANRE", "id": "Q4KME6-1", "name": "GRB10-interacting GYF protein 2", "aln": "-MAETQTLNFGPEWLRALAGGVGSS-----------------IVASPPLSPALPKYKLADYRYGREEMLALYVKDNMIPVDLHDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGR--GGGTVAGAPRGRSSSRGRGRGRGD-GFYQRSFDDVEGGFGRGG-REMHRSQSWEER---GDRRFEKPGRKDPDGAPAHFPLNHIRANYED--PAAVN-ARKFIHAECDNWRTTRDELNGEEDDNGWRLAGARRENERWCPPSPDGPRSAGWREHPDQRRR---FGFGDEERS---GYRRPRSGSGSAEEERDSLPEWCLEDAEEETGTFDSSGAFLSLKVRALEKAPKEPILEEAELDFRPLEEND--EYAEKDDSETEQTKDTDTNTRHESDRNEENCKSEEPSPVAVPFS-AVVTPPKATTPAPIQPVHLEKAEDKERPSERTTLPEIRHELSKAPLHTALSNSIVEAISIPHVANKLPDLPVPAPSVLPVKSVPPQSQQVKPIEMPVSVPPALLRSTGSVGPISRPSALPSDLDEDEGLKHFEQEAEKMVAYLQDGGVDDERLASKIGP---KPSALPITNEAAFKWFYKDPQGEIQGPFNNQEMSEWFQAGYFTMTLQVKRGCDEMFQPLGEMIKLWG-RVPFTP-------------------------------GPTLPPILGDADQERMKRQQE-----------------------------INALNMYQLQQMQYQYLLRQQYALQQKVLNSAPPPPPPPQQQLNLLLHQALKIRTPE---------------------------------PQQSLLPPVTRSMSVP----DSGSVWEMQNPSTQASCSP-NMQPAAPSTWEGSSVWDLPLDNMPQASSIEQLQ-LEKAKALKLEMERREAELRAKR-----------------------------------EEEERKR-------LEEALRARQEEERKRLEEEELARRKQEEALKRQREQEEAQR------------------------------------------RKKEEEERLAQEEALRRLEERRREEEERRQREEFLRKQQEEERRKQEELEAQRRREEEKRLEEEAAAAAAALLRQQQEEQKKREQEAQRQQELQRQRQ------------QQQEALRRLQQQQQQQQLAQMKLPSSSKWGQQSTTANSLSQSQNALS-LAEIQKLEEERERQTREEQRRQQ----QELQR--VQQQQPQTKLPGWGSVAKQPMATKSLLEIQREEAQQMKQRKDQQQQQQQQQQPPPQPQPQQHSTNTQQNRTQ----------------NRAAINTSVWGSVNNVSSN-WMMD--SSVWG---------DTQNSNIGFWDEAVKEAAPPQTTRKSHTPKNKGNANLSNSS--SGKASKK-------------VEEEEKLLKLFQG------------ANKNQDGFMQWCEQTLHTLNTANNLDVPTFASFLKEVDSPYEVHDYVRAYLGDTPQAKDFAKQFLERRAKQNDNQQKPQQGQQQKQQ-----------------ESVWGIREVPQSVLLQQQQQQQLQQQQQQRFETVTSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETVEDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KQM6-1", "uniprot_id": "GGYF1_DROME", "id": "Q7KQM6-1", "name": "GIGYF family protein Gyf", "aln": "---MTDSMKFGPEWLRNMSAEPSGSPSTYNVGNAAQNNSIGGHNLGNNTAASASRNLFPEYRYGREEMLSLFDRNCLLPQILPS--FKKLFVEKVQCPLALTPSSEEDINQNSLGNNSRPAWLQRSPSGFGSASRGSGRGGTVDRGRMRGKSA---YHPIYQRPSGLYDESLSVISKAERTWSDRNGTGDSAATTTSTSGSG-----------ALDWNGTPSSSPRKDYSNNHRNLENWRRTRNE-DGSGDGPSSSGSMSGPDIAGWRSGVVGGSTNAGFGTNSHRWGRSTSWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKGSGIGAAEGVGSISHPRLSSSKISQLWTVNNAAGVDADENLPEWAIENPS--KLGGSFDASGAFHGDTDLKPIKSSHNTLKTKSLDSYDDVKRPKSKDLSDPDSGNDITPETSLTKDTNTTAVQEEVESSLSPISSTTTKEVIHGDISDRIKEVADEVEKLIMDDDHKISSNQSQHQNHDGFTAALPRMADIEINVKPSVTAVHR--------QAPSTMPIQITPTITDVAPPSHAVVSFSDHETMQHHNMHHLPQFPMIPTPHIITPNLNELWFYRDPQANVQGPFSAVEMTEWYRAGYFNENLFVRRYSDNRFRPLGELIKFCHGNMPFTHSHLLPSPIELENIPVGQIPAPLTASLSITPHKPSPIPIALSVVEQQLQQQRDEQLKANVTATAEALRAAIKGSFGGNSIGNTSHLLTMRFQMLQDQYIQHQEYQILAELSKNECFQRLSAVEQETVVRRKVQLLGLPEYLISLNGLSNSLSVLNPVAGRQLYRAVVEHAKKDQQHIFANTEQQRSVGNLLDANNFILNAQIMIQQSQQEVGPLVSSVDCIMQGGTAADLNKPNEIPRNELDLINEYNLRMLLRGQPTSTQQQPPALTNSATENLPGVDFLTETQLLERQNLMIPIWLPPNNNKQQETDQQWAEMSNADASLWETANLNEERNEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSGNVVNHTALEELDQSPQNLKGSHNQKIVKSLVSDIQQNHNEELNSHQHQVKQANKQNLNTKQNAAQSALKPINNENDRKREQTEEKKRQREERKRQQLEDDKRR--ALNESEEQTRQIQEEKERQQQIQAQRRKALLGNVHSLSVQNGMSGTLASAQSKKNDDAKTAEPQVSSRLPSTSVAPWSFQLQNSMRSAPGLAEIQKAERRERRADQQRHQELLDKQLRANAAAAAEANDALLKWQSTP-ASAPVMSLAEIQAEEARRLANDLVDRQRRRELEHHQQAPLSSAVLVTSATSNIWGNANKAWSSSAAQSLSLKTSSGTGLWDEPNPLGSNGSGTSGTSSVTAAAVLAGGLNSANKSTLQAQNKSSALFASPRNLRKSQTLPALSNPEKSNKNGPGQRPEKQKLAQTRSKGAAVSIEEKDRERKLNAKSQQSSTDQAISKVNEYENEFTSWCIKSLDNMSAK--VDVPTFVAFLQDLEAPYEVKDYVRIYLGDGKDSLDFAKQFLERRSKYKSLQRAQKAHN----------------------------DDMCKPAPAITPSAN-------DYADSKNKQKKIKKNKMTKMDARILGFSVTAAEGRINVGIRDYVEGP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02875-1", "uniprot_id": "SYH1_YEAST", "id": "Q02875-1", "name": "SMY2 homolog 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPINSLAFDLHS--VKLADANSDTAALSNSNTPTMNNAALLQRPSSIMDSIGVQRVPS---PFVPGSNAISGASTVPFN----AYDAEITGSPLQISANQENNSAFSAASSNLHMNASSP--------SVLNKPSSTFPNVAPYLYNATGPAPNVGNQPPPPG--------------------------------------------------------------------IESQWKYIDSNGNIQGPFGTNNMSQWYQGGYFTPTLQICRLATS-PEPFGVNDRFIR---------------------------------------------LGELTTLVNNYQDP-----------------------------FVAFDFIVIRALNAVPLVAPTSSEKQKVESRD-LIPVADVHSDDFTYEEILGLKFED-----------------------------------GSYYHETQVWVPVDG-----RHITKVDRIPKIS-------------AYTAPLSTTSSRSNKTTSSHEEKVPSHEEASPEEQEVFSEEG-------------------------------------------RTVSNITNEEESIVKNPTKQEEESRGSEKEQNILDQVQPEIEEVDRKD--VIS--------------------------------------------TADEPKSKDTPQMTSEEQKRFAKAELMAQKLLEEQQRQEEEKKRREEQRKLKKEKKLKQKQKKEEEK---LKKKKKEEGKLEKEKQKE--------------------LLNNILTGDTETPSSENTATSITTNLAPWANKKPEGAVYNQISSALEDLKKENSSKKEKKPNRTQLDREQALKLQKEILS--SAQIPKTQTGSAWGIKPQQPIKVDIKGELMKDSTKINSQSKINKANNGDIKPDSTFIEEQKKLWEQVQKKTKKFN--------------RASSLDDFISRTPSPSSSALNSSNTSNAWTTVSSKS--TTHIASTMPVAGNQSKSYISLDTLRSSGGLSTATKTKMSDKSKQIGSSTSIP--------TLKARQVKPSRIPAYPG----------NASVSKRQEFLRWCRSQLKLNTGVQPDNVLEMLLSLPPGSESKEIIADTIYSYSSTMDGRRFATDFIKKRLECEEEIN----------------------------------DPLSWSEVLAMPEGS------SEDWEFQVVGKKKGKRF-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32909-1", "uniprot_id": "SMY2_YEAST", "id": "P32909-1", "name": "Protein SMY2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIAPDSQRLFGSFDEQFKDLKLDSVDTENNNTHGVSTILDSSPASVNNNTNGAVAASVNTVPGSTFRSNTPLLGGRHPLSRTSSLIDSIGIQRAAS-PFSSMKEPFIPQSSGVMSSSFWHGDHPESRVSTPVQQHPLLQRNESSSSFSYAANLGVNLSTHSLAVDITPLSTPTAAQSHVNLFPSSDIPPNMSMNGMSQLPAP-----------------------------------------------------------------VSVESSWRYIDTQGQIHGPFTTQMMSQWYIGGYFASTLQISRLGST-PETLGINDIFIT---------------------------------------------LGELMTKLEKYDTDP----------------------------FTTFDKLHVQTTSSDSINLNLAPYASGVAATGTIKATENDIFKPLTHDNIWDMDGGT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSKGVDIKLASATTIS---------------------------------------------------------QTDESHKQEYKSTTMLEKGKKEKSESVAKALLDEQEKRNRELKRKEEARLSKKQKQKEDDLLKKQKE----QKEQKEKEALEAEKQKK----------------------SEKTKKDTQTQTEGFKTSKDLPSLNSSSANPAPWASKVKVNNAIETSIKNGVSSTGKKKGEPLGLQQRNSKEEKQKEE--------LKSVLNWANKSSLPSNQTIDIKSQFQKSPKGMK----ESSPLKELEDPNFIEEQKKLWEKVQ-------------------------------SSSKQVKSTSSASTTTSSWTTVTS-----KGKAPIGTVVSPYSKTNTSLNSSLTAKTSTTSTTTTFASMN-----------------------------------------------NVSPRQEFIKWCKSQMKLNSGITNNNVLELLLSLPTGPESKELIQETIYANSDVMDGRRFATEFIKRRVACEKQGD----------------------------------DPLSWNEALALSGND------DDGWEFQVVSKKKGRKH-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: . .: .: . . . : . . * * *.:.:::*** *::*: .*** .* : * ..:* : . : : .: . : . : : : :: . :* . :: . : : : :..: . :: :. . ...::: : * ::: . : .. . : . :: . .. :.: : * . . : :.: : . . . . :. . . . .. :. . .: * ** . :. . :* : * . *: .. :. **.:*:::* : . . : ** :. ", "identical_positions": 29, "similar_positions": 134, "identity": "1.76%" }, { "cls_id": "homologset.agr.MGI:2138605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08326-1", "uniprot_id": "MSS4_RAT", "id": "Q08326-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPCELQ---NELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPDLVDGSNPDGDVLEEHWLVNDMFIFENVGFTKDVGNVKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GKW6-1", "uniprot_id": "A0A8I6GKW6_RAT", "id": "A0A8I6GKW6-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPCELQ---NELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPDLVDGSNPDGDLLEKHWLVNDMFIFENVGFTKDVGNVKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X96-1", "uniprot_id": "MSS4_MOUSE", "id": "Q91X96-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPCELQ---NELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPDLADGSNPDGDLLQEHWLVNDMFTFENVGFTKDVGNIKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47224-1", "uniprot_id": "MSS4_HUMAN", "id": "P47224-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPAEQP---SELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPALSDGSNPDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLP3-1", "uniprot_id": "MSS4_DROME", "id": "Q9VLP3-1", "name": "Guanine nucleotide exchange factor MSS4 homolog", "aln": "-MTEEADFS---EQIT--DGKNKSNVRCQFCNCLMLKAQEGTYNQEE-----VDVPLMTQKQDRTADS-LNSEPLKDFWLVKDMMTFENIGFSNTVDGRKFLVCADCERGPVGYHD-------LSTR-HCYLALKRVVHKDT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32601-1", "uniprot_id": "MSS4_YEAST", "id": "P32601-1", "name": "Protein DSS4", "aln": "MSKATCSFEGCHSAVITINDDNIINLPEQVHSEFKLLENRTMRDATPSESNFLVVPDVWDFDNVGVSREIPSSILGDLSDKSDFVFEYGNSSWKIKKCLKYLICADCDKGPIGIICKVQDQTKNEERVLHLLSLRSLQIMGRN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : :. * : * . * . : :* : . . .. * . .*:. . . : *:*:****: **:* . : ::*. : ", "identical_positions": 16, "similar_positions": 33, "identity": "11.19%" }, { "cls_id": "homologset.agr.MGI:2138614", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYE0-1", "uniprot_id": "A0ABK0LYE0_RAT", "id": "A0ABK0LYE0-1", "name": "", "aln": "------------------------------------------------------------------------------------------MPEDLALESNPSDHPRASTIFLSKSQTD---VREKRKSNHLNHVSP----------------------GQLTKKYSSCSTIFLDDSTVSQPNLRTTIKCVTL-AIYYHIKNRDANRSLDIFDERSHPLT-REKVPEEYFKHDPEHKFIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPTNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLNFLFAPLSKERAQNLEAISRLCEDKY-------------KDLCRAAMRRSLSADNFIG--IQRSNAILS-----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YUJ3-1", "uniprot_id": "CCYL1_MOUSE", "id": "D3YUJ3-1", "name": "Cyclin-Y-like protein 1", "aln": "METRIRAAQLKGRGG------AFPKLGR--RAGPAEPDYESEVYEAAAGDAVAVAPAPAAAVEPAELDFGAGEG------HHLQHISDREMPEDLALESNPSDHPRASTIFLSKSQTD---VREKRKSNHLNHVSP----------------------GQLTKKYSSCSTIFLDDSTVSQPNLRTTIKCVTL-AIYYHIKNRDANRSLDIFDERSHPLT-REKVPEEYFKHDPEHKFIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPTNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLNFLFAPLSKERAQNLEAISRLCEDKY-------------KDLCRAAMRRSLSADNFIG--IQRSNAILS-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N7R7-1", "uniprot_id": "CCYL1_HUMAN", "id": "Q8N7R7-1", "name": "Cyclin-Y-like protein 1", "aln": "MGNTLTCCVSPN---------ASPKLGR--RAGSAELYCASDIYEAVSGDAVAVAP---AVVEPAELDFGEGEG------HHLQHISDREMPEDLALESNPSDHPRASTIFLSKSQTD---VREKRKSNHLNHVSP----------------------GQLTKKYSSCSTIFLDDSTVSQPNLRTTVKCVTL-AIYYHIKNRDANRSLDIFDERSHPLT-REKVPEEYFKHDPEHKFIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPTNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLNFLFAPLSKERAQNLEAISRLCED---------------KDLCRAAMRRSFSADNFIG--IQRSKAILS-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CI4-1", "uniprot_id": "CCYL1_DANRE", "id": "Q08CI4-1", "name": "Cyclin-Y-like protein 1", "aln": "MGNTVSCCVSPS---------GSPKLPR--QVERLEDYQN-------------------------NTDISDDTG------PYLQHISDREVPDDLALESNPSDHARASTIFLSKSQTD---VRDRRKSNHINHVSP----------------------GLLSKKYSSCSTIFIDDSTVSQPNLKSTIKCVTL-AIYYHIKNRDSDRSLDIFDEKMHPLS-REQVPDDYSRTDPEHKLIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAELDICPSNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLSFPLEPLSNERAQKLEAISRLCEDKY-------------KDLSRVAMRRSFSADNLVG--IRRSNAVLS-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5T2Q4-1", "uniprot_id": "CCYL2_HUMAN", "id": "Q5T2Q4-1", "name": "Cyclin-Y-like protein 2", "aln": "MGNILTCCVCPR---------ASPGLHQ--HQG-LVCHCESEIYEAAAGDLIAGVP-VAAAVEPGEVTFVAGEG------LHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD---VQEKKK-KQLCKVST----------------------EHFTQQYSSCSTIFLDDSIASQPHLTMTLKSCDLGTILSYQAKRDAHRSLGIFDEQLHPLTVRKEVLEEYFKYDPEHKLIFRFVRTLFKAMRLTAEFAIVSLIYIERLVSYADIDICPTNWKRIVLGAILLASKVWSDMAVWNEDYCKLFKNITVEEMNELERQFLKLINYNNSITNSVYSRFYFDLRTLAHNNGLYSPVYLLDRERAWKLEAFSRMEQD---------------KVFYSAAKNGSLSADDLIH--LQRAKAILF-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKF0-1", "uniprot_id": "Q9VKF0_DROME", "id": "Q9VKF0-1", "name": "", "aln": "MGNKNSCCAYSSPQSDRKSKDMPPVFEERIIQLGHPPHTSQHQLDGHHGSASAVHLHHHHHGHNQQQNQQGGGGDNYENQQNLQHISER---EALEGEEDPSVDPTAATMFLERSKVENGGMTRKRSQQQIAQQAGSGGGGGGGGGGGSTPGGNSCGGGGGMKKSSSCSTIYLDDSTVSQPNLKNTVKCVSL-AIYYHIKNRQSDRRLDIFDEKLHPLT-HDQVPDNYDTHNPEHRQIYKFVRTLFNAAQLTAECAIITLVYLERLLTYAELDVGPCNWKRMVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRTLAEANELNFPTEPLSKERAQKLEAMSRVMQDKVT------------AEALKNGIKKWSSMDNISQGGPRRSVAILS-----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C7X3-1", "uniprot_id": "CCYL3_HUMAN", "id": "P0C7X3-1", "name": "Putative cyclin-Y-like protein 3", "aln": "---------------------------------------------------------------------------------------------------------MACAVFQIPP-------------------------------------------WHLDRKYGSCSTILLDNSTASQPDLR-------------HTLERYANRSLAIFEEPVHPLP-QEKLPGKSFKHDPKRNCIFRHFCTLFQVIKLTAPCAIVALVYIKRLLTSANIDLCPTNWKKIVLGTMLLASKVWRNHGLWSVDDSQNSKDTAVENMSKMEKCFLELLEFNIHVSASVYAKYYFDLCALANDHDLYFLFSFLHKDKAQKLEGHTSQHSLSLGPCRVGMENYATYSPLSSQPVLGALSLAEVLPQEIKQEIHQVLMDHGVPCHYTCFLLHPEDSTLERFLVLHSIQGLQEDSVLCKVEIHGLSPQPQTYQSHFRSPSLAELLNRISGTCRNHFAGMQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.::* . :: .***** :*:* .***.* : :* :.* * **:* ***. :.:: . :*::. *::.. ***.. :*** **::*:*::**:: *::*: * ***::***::******* : .:*. * .: *: :**:*.::*: **:*:::* :. ***:::**** :**. : * * .::* :**. : . * :. :: : ", "identical_positions": 78, "similar_positions": 84, "identity": "15.42%" }, { "cls_id": "homologset.agr.MGI:2138628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ80-1", "uniprot_id": "OBSL1_RAT", "id": "D3ZZ80-1", "name": "Obscurin-like protein 1", "aln": "MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVLWEKGGQQLVASERLSFPEDGAEHGLLLSGALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAPEPEPQSSECPPPPPGT---------------------------GEGAPVFLTGPQSQWVLRGAEVVLTCQVGGLPEPKLYWEKDGMALDEVWDSSHYTLEPDRGASDGGASLTLRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPHENPPQDPDEPPVR----------------------VIEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHLEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIVVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLVIHRLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETQEAGVQGCWSRDGEELPATCQ---SSCGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPPVLVEMFKGQKN-TVLLTWKPPEPPP--ETSFIYRLERQEVGSEDWIQCFSIEKAGAVEVPGDCVPTEGDYRFRICTVSEHGRSPHVVFNGSAHLVPTARLVSGLEDVQVYDGEDAVFSLDLSTIIQGSWFLNGELLKNDEAEGQVEPGALRYRIEQKGLQHRLILQTVKHQDNGALVGFICPGVQDSAALSIQESPVHILSPQDK-----------VLLTFTTSER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVLTCELSRVDFPATWYKDGQKVEESESLVVKMDGRKH--------------------------------------------------------------------------------------------RLILPEAQVRDSGEFECRTEGISAFFSVTVQDPPVHIVDPQEHVFVHAITSESVMLTCEVDREDAAVHWYKDGQEVEESAVIVLEKEGPRHRLVLPAAQPSDGGEFQCVVGDERAYFTVTITDVSSWIVYPN-GKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVLESPALLLEKEDTIRRLVLPSVQLEDSGEYLCEIHDESASFTITVTEPPVRIIYPQD-EVTLHAVSLECVVLTCELSRVDAPVRWYKDGLEVEETEALVLQSDGPRRRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPVARSLDLQFGAPGHVELRCEVAPAGSQVRWYKDGLEVEVSDALQLGAEGPARTLTLPHAQPEDAGEYVCETRDEAVTFNVSLAELPVQFLAPEAVPNPLCVVPGEPVMLSCELSRASAHVSWSHNGNPVKQGEGLELRAEGPRRILCIQAADLAHTGVYTCQSG--------------------------------------------------------------------------------------TAPGAPSLSFNVQVAEPPP--------------------------------------------------------------------------------------------VKLVSELTPLTVHEGDDATFQCEVSPPDAEVTWLRNGAIVTPGPQLEMVHSGSSRTLIIRGCQLKDAGTVTARAGATDTSARLHVRETELLFLRRLQDVRAEEGQDVYLEVETGRVGAPGAVRWLRGGEPLPLDSRLTTAQDGHVHRLSIHGVLLTDQGTYGCESHHDRTLARLSVRPRQLRELRPLEDVTVHEGGSATFQLELSQEGVTGEWAQGGVRLHPGPKCHIHSEGRTHCLVLSGLGLADSGCISFTADTLRCAARLTVREVPVTIVQGPQDLEVTEGDTATFECELSQTLADVIWEKDGQALSLSPRLRLQSLGTRRLLLLRRCSSSDAGTYCCAVGTARSGPARLTVREREVSVLGELRSLSAREGDSATFECTVSESETTGRWELGGRALRPGGRVRIRQEGKKHILVLSELRTEDTGEVCFQAGPAQSLARLEVEALPLQMCRRPPREKTVLVDRRAVLEVTVSRPGGHVCWMREGVELCPGSKYEMRSHGTTHSLVIHDVRPEDQGTYSCQAGQDSADTQLLVEGDD------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YYU8-1", "uniprot_id": "OBSL1_MOUSE", "id": "D3YYU8-1", "name": "Obscurin-like protein 1", "aln": "MKAGSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVVWEKGGQQLVASERLSFPEDGAEHGLLLSGALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAPEPEPESSECPLPTPGT---------------------------GEGAPKFLTGPQSQWVLRGEEVVLTCQVGGLPEPKLYWEKDGMALDEVWDSSHFKLEPGRGASDEGASLTLRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPRESPPQDPDENPKP----------------------VLEPLKGAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHLEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIVVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGAVRRLVIHKLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETQEAGVQGCWSRDGEDLPDTCQ---SSCGHMHALVLPGVTREDAGEITFSLGNSRTTTLLRVKCVKHSPPGPPVMVEMFKGQKN-KVLLTWKPPEPPP--ETSFIYRLERQEVGSDDWIQCFSIEKAGAVEVPGDCVPTEGDYHFRICTVSEHGRSPHVVFNGSAHLVPTARLVSGLEDVQVYDGEDAVFSLDLSAIIQGSWFLNGEQLQSNEPEGQVEPGALRYRIEQKGLQHRLILQAVKHRDSGALVGFSCPGVQDSAALTIQESSVHILSPQDK-----------VSLTFTTSER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVLTCELSRVDFPATWYKDGQKVEESESLIVKTEGRKH--------------------------------------------------------------------------------------------RLILPEAQVRDSGEFECRTEGVSAFFGVTVQDPPVHIVNPQEHVFVHAITSECVRLTCEVDREDTTVHWYKDGQEVEESDIIVLENKGPHHRLVLPAARPSDGGEFQCVAGDERAYFTVTITDVFSWIVYPS-SEVHVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLEKEDTIRRLVLPSVQLEDSGEYLCEIHDESASFTITVTEPPVRIIYPQD-EVTLHAVSLECVVLTCELSREDAPVRWYKDGLEVEESEALVLQSDGPRRRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLQFGAPGHVELRCEVAPAGSQVRWYKDGLEVEVSDALQLGAEGPARTLTLPHAQPEDAGEYVCETRDEAVTFNVSLAELPVQFLAPEAAPNPLCVVPGEPVVLSCELSRASAQVFWSHNGSPVQQGEGLELRAEGPRRILCIQAADLAHTGVYTCQSG--------------------------------------------------------------------------------------ASPGAPSLSFNVQVAELPP--------------------------------------------------------------------------------------------VKLVSELTPLTVHEGDDATFQCEVSPPDAEVTWLRNGAVITAGPQLEMVQNGSSRTLIIRGCQLKDAGTVTARAGAADTSARLHVRETELLFLRRLQDVRAEEGQDVHLEVETGRVGAAGTVRWIRGGEPLPLDSRLTTAQDGHVHRLSIHGVLLTDQGTYGCESRHDRTLARLSVRPRQLRELRPLEDVTVHEGGSATFQLELSQEGVTGEWAQGGVRLHPGPKCHIQSEGRTHRLVLSGLGLADSGCVSFTADTLRCAARLTVREVPVTIVQGPQDLEVTEGDTATFECELSQTLADVIWEKDGQALSLSPRLRLQALGTRRLLLLRRCCSSDAGTYSCVVGTARSEPARLTVREREVSVLRELRSVSAREGDGATFECTVSETEITGRWELGGRALRPGGRVRIRQEGKKHILVLSELRTEDTGEVCFQAGPAQSLARLEVEALPLQMCRRPPREKTVLVNRRAVLEVTVSRPGGHVCWMREGVELCPGNKYETRRHGTTHSLVIHDVRPEDQGTYSCQAGQDSADTQLLVDGD-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75147-3", "uniprot_id": "OBSL1_HUMAN", "id": "O75147-3", "name": "Obscurin-like protein 1", "aln": "MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGS---------------------------GEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAP----------------------VVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPVICQ---SSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPPILAEMFKGHKN-TVLLTWKPPEPAP--ETPFIYRLERQEVGSEDWIQCFSIEKAGAVEVPGDCVPSEGDYRFRICTVSGHGRSPHVVFHGSAHLVPTARLVAGLEDVQVYDGEDAVFSLDLSTIIQGTWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDR-----------VSLTFTTSER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKH--------------------------------------------------------------------------------------------RLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSSWIVYPS-GKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRD-EVTLIAVTLECVVLMCELSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSG--------------------------------------------------------------------------------------AAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSELTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLRPLEDVTISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVSFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSTHTRLLVEGN-------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5Q8-1", "uniprot_id": "A0A8M9Q5Q8_DANRE", "id": "A0A8M9Q5Q8-1", "name": "Obscurin-like protein 1", "aln": "MDVFGG----APRFLAYPRPVVVQSGTDAVLKCQIGGDPRPAVIWERNNEKIHPEGRYRVFEDGNVYNLIITSVTMEDSGQYICKAKNCIGETYAAATLKVEGEAQ-EMEVR--------------------------------------EENKPRFLIKPLSTRVGRGEDAMFSCKLWGNPRPEVMWEKDGKKLNEIFESTHFSIS-----YQDGGWFQLKIFKTRAPDGGVYTCKARNEFGESLAGAVLLVDAGPGHEDEGNRNGYTNGHWKAHQGKQRSGRQVATRLKDDPLPNSAKVKMFAVTEGKHAKFRCYVTGKPKPEILWRKDGKLILSGRRYLLYEDREGYFTLKVLYCKQQDNGVYVCSASNTAGQTLSAVHLIVKEPPVRFKQPLNDLQVWERDLAVLECEVPEDSVPITWYLEDRRLQPGAKYGMEEWGTKRRLTIRDIGVDDDGIYLCEMADGGRSIAEVAVKGTIVRKLPRKVDVLEGENAAFCVEVEEEEMDIHWYKDGTELRETHQTILKSFGRTHILVFVNTTPQDSGLVMFYVGRSKTSSQLRVKAARHCPPSCPIGVQINTERAN-AALLSWFPAQDSR-KNPPSGYIIERQEVGSQEWLQCLTTDSATSVEILGDSVPCEADYRFRICSVNKYGRSGNVEFPRAVHLVPVARIQAPLQDALVPEGQDACFTIELSASVIGTWFLNGNQLQDDE----------RFSIRRSRTHQSLRIRGVRDTDNGAEITFIAYGIRDSAALYIQAPLVKFTPLSEMDRNKFVEVGNPIVLYCELSDPEAPVRWYKNGVELQSMEGLHIQSEGTMRRIVIQSAEFSHSGVYSCDAIDDVIRFNVEVEAPPVRFSVVPEGKRNKSIEVGTTIALQCELSDPVAQVSWYKDGVKLLPQSGVDFKSVGTKRELVVQSAEFYHSGVYSCKTRGDAVHFSVDVKAPPVRFSAVPEVKRRKCIEAGCPITLQCEISDSAAQVQWYKDGNLVESGVDINSDDCMRTLSIQSAHPSHAGVYSCTTKDDVLEFHVEIRAAPVRFSAVPEAGKNICTEAGGHFELCCKVSDPAVHVSWFHNDTQLQPETGLDVQSEGEARTLIVNPAEPRHSGLYRCETSDDSVQFTVDIKDPPVMFSALPDTVKNRLIEADNSTDLYGEISEPNAKVCCYKDGVELVSKSQPHIKSECTRRTLAVKTAQPSKSGWYDYVRTGDVFQFNVQDQVSPTILADPEVQKTKFVEEMESVVLPYEISDPAPYVSQTKEEKVMLPQSKPEPELESNSDFDPESKHEVHLDASRGALIIHSPETSLVKVKCPKTPEDPIQFEMDQAELSHYEVFSGEIYDDSVQCTLDTKAPPVMFSTIDEVQRNKCIESGRPFKLQCEVSDPDAQVWWYKDGNEVLPQDGIVIGSEEGIRTLSVQAAELCHSGTYRCQMNDDAITFHVEIKAPSLKFIPISEVEKNKSTEVDSPIVLKCELSDATSEVLWCKDGRELAPNPELNFQKDENTRKIKVESAKLSDTGNYTCHVQGDTVSFKVDDQAHPVRFSALPEIARNKFIEAGCPIILQCEISDPTAQVSWLKDGVELQQQSGLDIQSEGTMRKMIIHSAELKHSGVYSCEAVDDLIAFKVDVAAPPVTFAYIPEDDLHRNIVEQDNILLHCQVSRSDATAQWYKDGVELKSTSNVLIEVENDIRRLIILSAHLSDSGTYTCRAGDSALVFKVNVREPPVMIVYPKEDVHLDRHVPEEIVLSCELSRPNGKVTWFKDGQKLQESENIKLKTEGPYRRLKILHSGIEDSGEYVCDTADDSIFFNLNIKEPPVRIVSPSQSQMELCQQTSERMVLSCEISRPNATVRWYRDGLEVEESDSLILEVDGVYRRLIIPKPTVKDSAEYVCDTTDDSVTFFVNIAEPPVRFIRPRKMAYGVEKLVGEIVVLECEVCRPNAEVSWKKDGDEIEENSNVTITEDGTNRQLTIHSADFEDAGQYVCDARDDVMDFLVKIKDPPLKILRKADIETKRQFMVSDAIVLKCEISRANGVVNWLKDNEKIDGNEHFTCEEEGAFRSLIVLNAELRDSGEYICDAQDDKVVFSVTVEEAPVSIVGNTQKPKHCILLTGDELSLECEVSRVNAVVQWYCNGRLLKQDSRTHIESSDTMRKLVISGLQTSDSGEYLCDATDDKMITMLTVQDLPFKFIKKDEKTNISAYEEDSLTLRATVNRVNAPIKWQRGRDLIRGDRFNTTSDGNTHYLTINPLKRGDSGEYTCHLGTDEMHFSVHVKAMKVKFSKPLENIAGLK---GSNVVLKCELYKSKGDVQWLKDSQEIAASRHFTIRAEGRVRSLTIHNITEDDAGEYACESKDERTSATVMVNIPRIVEFVAELHNMTVMEGEDATFKCVVSPEDAKLSWFKNGQHISSNEKFNISSNGLCHMLHIKNCQVSDSCSLTAEAEGVISRALLQVQEAQVLFTKSMDPVVAEEFGEATLEVEVSTE--TAEVQWMRQGVVIHPGSKFTLRQSGRKRSLTIHKLTLLDRGTYSCETLHDRTQAKLSVEPRKIKIRKGLTDIQTIERETASFEVELSHSNVEGVWQKDGHVLKTNNRLRMTAQGRVHSLTISGLTLDDTGTYIFSVDNVRSLARLDVKEIPVSILKKLDDIRQPEGSGVTLECELSRHNIDIKWTKNGVQLKPGKNHRIYSMGRKCFLQILKCELGDSGLYVCDAGDATTS-CSVDIYERELEILQSLEDLDIQEDQNAVFMCEVSLDDVPGEWFKNGEKIKPTSTIKIRQEANKHFLLICNVKEEDSGEIKFVAKNVESTAYLEVEALPANIVK-PLQDKTVLEKTRAIMDCTLTNPRCSIRWYKGPNVILPSEHFEICSEGCYRKLVIQQVLLEDEGTYSVQVGNYTSSARLTVEAQSILMVRELQDVNVTAPADACFECEISLPVAKAPTWTLNGETLNPSPNVVLEKMGTVHRLTLKQTSEEMSGTVCFITGRTKSTAQLLVRRNN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BDK6-1", "uniprot_id": "A0A8M2BDK6_DANRE", "id": "A0A8M2BDK6-1", "name": "", "aln": "MDVFGG----APRVLGYPRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVYTLNISGVTMEDAGQYICRAKNNIGETYAAATLKVQEETQ-EQQTQPAQAPPPQQNDVQVIPPEQDMKMKIQQQVGVEKKKDPFQDSKPYFLIKPLSLRVDRGEDAAFSCKITGDPLPQVVWEKDGKQLNEIYESAHYHVG-----QQDGGWFQLKIFKTRTPDGGVYMCKAVNKHGEAITGAVLLVEPIPEHREGSMTNGYTNGHYSPQHSRAKHSK--------EPHLNVSKAKKFTVTEGKHAKFRCYVTGKPKPEIVWKRNGEIIMPSRRHLIFEDREGYYTLKVLYCKQQDTGLYICAASNALGNTLSAVQLSVKGPPVRFKRALQDSEFRERDVAVLECEVPEESISTAWYLEDQRLQHGNKYNMEQKGTWRRLTIQNVGADDDGVYLCEMPDGGKTIAELAVKGTIVKKLPRRLEVMEGENAAFFVEVEQDDMDICWFKDGLQLQETHQTIIKSFGKTHILVFVNTSYQDSGTITFMAGRSTTSSKLRVKTARHCPPICPVGVQMNTDCCQNGVVLSWSPSPNLQNSTTKSVYVLERQEVGSQEWQRCLTTETGTSAEVLGDSVPCEGDFRFRICCVNKYGRSGHVEFPKVVHLAPGPKIKSPLKNAVVTEGEDAVFSIELSSELIGTWFLNSQQLQQSE----------HFSMTQSKNQHILRIRQVPNVYDGAEITFIATGVRDSASLQIKVCEVKFLPLSEMDTKKSTELGNPIVLYCEVSQPTATVQWFKDGKELHAEDGLNIQSDGNMRRIIIHSAEYSHSGVYTCQSNNDILTFNVNVEAPPVLFKEIKAEERQK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAMELDP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVLTCEISQPEAPSCWFKDGVAVFQSDNITIQSEGNMR--------------------------------------------------------------------------------------------RLIIRSAELVDAGTYTCQAGDQTMSFSVNIKEPPITIVDPKDDIHMERYVSEEIVLNCELSRSNGEVQWFKDGLKLQETDNIRLSAEGPYRRVIIFCASKRDSGEYVCDAGGDSVFFQLLITEAPVRFVSPSESEVEVCIMSSEKLVLNCEISKADAEVCWFCDGMEVDENDNLKLEDDGIYRRLVIPCTTIDDSAEYVCETADDAVTFWVKIEEPPVKLSSSKQSGSITESFAGDPVILELEVSRENAEVCWMKDGMKVEESSNITITENGLTRKITIHCPTLKDSGIYTCNAIDDTMDFKVKITEAPVTILNKDQIKNEHKVMLYDDVVMECELSSANGVVTWYKNGSPIEENERFCLEEEGTFRSLVILCAELQDSGEYTLDAKNDTFSFHVTVQEPSVKIIGNSGDPDYQEMVTGDDLILACEVSRANAPVKWLFNEKVLIPDERTHIESQGTLRKLTISNILVSDSGKYMCDAVDDKMLTVVKVQEPPVEFLNKEEVNLVTGYEAEPVTLTAMVSRPNAQVRWLKDWTQISGERFHTASLGLTRTFTIDPLKKLDSGEYTCDANSDEMHFSLLVKDMRIKFVKPLVDTVAHK---DGMITLCCELCKAKADVQWKKDGVEIIPSRRFSIRANETERSLTIHRITKEDAGEYVCESKDDSTSARLRVELPRVVEFLTELHNTTVMEGEDAMFKCVVSPDDVQLVWLMDGEPIKPSDRFQIEQNSLCHTLIIHKVQLLDSSRITAEAEGLISKASLKVQEAQVLFTKRMEAVMAEEFGEATLETEVSLE--SGEVQWMRQGVVIQPGPKHKLSQNGCKRILTITNLSLSDRGTYRCETLHDRTQVKLNVEPRKIAIRKGMMDVETFERETASFEVELSHTDVEGVWQKDGLRIKPNNNWRVSSNGRVHGLTLSNLTMEDTGSIVFSAEGLRNTARLVVKETPVAIFKKLSDVRIEEESSVVLECELSRPNVDVRWQKNGIELKSSKTLRIYSMGRKRCLQILECSISDSGLYTCEIGDLSTS-CKLEVYEHELELITGLEDLWIKEDQNAVFMCELSMEDMPGEWYKNGSRIRPTSTIKTRTEGTKHFLLICNVKAEDSGEIKFVSKQVESVACLEVEELPVSIVR-PLRDRTALEKHRVILECTVSSPNCDVTWYRENEELESTEHMEIIQEGCYHKLVIQQVALEDEGTYSIEVGEHTSIAKLMVEAQSILVVKSIEDVEVRAPETAFFLCEVSVALIKPPVWTLNGETLQSGPNVRIDNQGTVHKLTFKTTSSDMSGTVKFTTGKAKTTAKLTVL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. .* .* .* :**** * .*::* *** : *:* * *:**: .:.: .. * . ** : * ::.. *:* *:*:*:* **:****::.* . : : . :. * ** * * * ** :. ::*: * * * : ***** *:*:::*:*: : *. : *:*: :* **.*** *:* * .*.: :**:* *. . : * * *.*********** ***:*** *: :*. ::..** *::.**:* :.******: :* *:*:*:* *: *:*****:* ** * :**.:.*:* : *:.:.****:**:. :. :*: **:** ** : *: *** *: : .****:***** . :::*:::***.*:::***:::*:*****.: **. : :: * :** :* * .* *: * **: ..: :*:* : * *.* *:: **** .:*.** *: .:: . : .:*:* *. . * :*******::* :*:: :.. :.*: **.** *.*::**** *. :*** :* * .**.* .:: : *::. * :*:** *:::**: : *:****.: *:..* :: : :. :: * :: * . .** : * . *::***:* *: *:: . .: : * *: ::* **:* * *** : :.. : :: :* : ***: .*.: *:* : *:: . : * *.:::**: ** *::.:.:. ..* : * **:.* : * *:*** :::*: : *. :** :*: : : *.**: * ...: :* : *.: :* *. .:: :. *::**.**:.:. * * * ** ** *. * *: :. ***::* :.**.**:*: *::.:* :.: ****:: .:. . : *:* *:.* :* * * *** ::**.. :.: :* ::.: .. :*.* :.*:* ** * *.:. .* *:. . . :. . : :.**:: *.. * * *:. :: .: : **. *:* : *: .*:*** :::.: . * * : * .*.::. *. : .*: : * **:**..* * * * : .. .:.:... * * *. :.:* * *:: .: .: *.: * *::::** ** **:** *:* *** *..: *: :* :... :.:: .. .: * :: *: *: :* .* . : * *:*:*:::** : :: * *** :. **.*.. .. *:*:* * : ..: . *.* : * * : * *:*** **: **** .:*.*.**:: : : *: * :*:*::***: .* * * :.* : .. . :: ::*: * *.:..* : *:* *:.: :* *** *:* **:*.: *:. * . ..:*****: *: * *:* *. . *: ::* : * : .* .*:* * * * : : : *: : :: *..: :*.:.*.* * :* : .*.* .* ::* . :: * *..**:*::.::: **:**: * : .:* * **** ** .: : * :::*.* *.::: *:: . : * : : . .: * .* :.***::* **:***. :.*: :: ::* *:.: ", "identical_positions": 551, "similar_positions": 618, "identity": "18.39%" }, { "cls_id": "homologset.agr.MGI:2138647", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920A9-1", "uniprot_id": "FCRLA_MOUSE", "id": "Q920A9-1", "name": "Fc receptor-like A", "aln": "MKLSCTLTQWALYVCPAVLLATQMLLAASSETLKCEGLVSTEQGSCQAAAEEDEGDEDDGDMTQSSEAGFQFKGY------TFSKPFHLSVSYDWLILQGPATLIFEGDTLVLHCRAWQDWPLTQVIFYRE----GSALGPPGPKSEFSITMVQKSDGGHYHCSGIFRSPGPGSREAASPVAITVQELFAAPVLKALPSSEPQEGGSVTLSCQTKLALQRSASRLLFSFYKDGRSLSVRGVSSELKIPKASEEHSGSYWCEAVTEDRQISKQSPQLEIWVQ-------------ALQKPTASETPP-TEALGPLPPPPASSAEQPRFSS----PDPHLHHQMQLLLKQIQDVRALLGHLVMELRDLSVYLKPGTTKVADK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B8P2-1", "uniprot_id": "FCRLA_RAT", "id": "Q3B8P2-1", "name": "Fc receptor-like A", "aln": "MKLSCMLIEWALYVCPAVLLATQMSLAASLETLKCEGPVSTEHSSCLAATEEDEGDDD---MARSGEADFRFKGY------TFSKPFHLIVSYDWLILQGPATSIFEGDTLVLHCRAWQDWPLTQVIFYRE----GSALGPPGSKSEFSIAVARKSDSGHYHCSGIFRSPGPGSQETASPVAITVQELFAAPVLKALPSSGPQEGGSVTLSCETKLSLQRSASRLLFSFYKDGRSLSSRGISSEFRIPEASEEHSGSYWCEAATEDRQISKQSPELEIRVQ-------------ALQKPATPETPPPAKAPGPLPLLPTPSDEQPVFSF----SDPYLTYRINRLLRQMQDVRILLGHLVMELRNLSAHRKPATTKS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L513-1", "uniprot_id": "FCRLA_HUMAN", "id": "Q7L513-1", "name": "Fc receptor-like A", "aln": "MKLGCVLMAWALYLSLGVLWVAQMLLAASFETLQCEGPVCTEESSCHTEDD----------LTDAREAGFQVKAY------TFSEPFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRD----GSALGPPGPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKSAAPGTAP-EEAPGPLPPPPTPSSEDPGFSSPLGMPDPHLYHQMGLLLKHMQDVRVLLGHLLMELRELSGHRKPGTTKATAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJF0-1", "uniprot_id": "A0A8M2BJF0_DANRE", "id": "A0A8M2BJF0-1", "name": "", "aln": "------MGSSALPLLLLLISILHSGLTEDGRDLPRPALTVTPDSAVFTGETVN-----LKCVIESDHSDWTYEWYKDSNCVTLQSDGHYTVNRDTLTIRG-AAESDQGQYWCKGVLGWVSIQSSTVSLSVKDLPRSSVTVTPDSAVFTGGTVNLKCVIESDHSDWTYEWYKDRNSVKLQSDGHYTENRDTLTIRGAAESDQGQYWCKGQRSGRPNSSLSSSAVSLSVKALP--TPTVTVGTSAAFTAETESSQSS-SHVFLSVKDLKPMSELGSELGRNAAA------------SLSSSSSSSSSLSSSSSSSPPPPGTPPLLVIGVSVGLSVFLLLLILLVLLLRHKKKGLYHVYDDVIKAENRNKGQSSLETLYVLN-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** : :: : *: . . * . . * ..: : : : .:.: : * *:.. * *. * * ::* * :*: .* . : * : . .*. .*.. . :: *. *.. :. . . .:: . .: * * * * ..: .*. ** * .. * *: : *.: * *: :..: . : : ..:* . : ...::. :. .: .. * :.. .* * : * :: :.: : ..:: . . . * ", "identical_positions": 39, "similar_positions": 109, "identity": "10.26%" }, { "cls_id": "homologset.agr.MGI:2138648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3K4-1", "uniprot_id": "SPB10_RAT", "id": "Q8K3K4-1", "name": "Serpin B10", "aln": "--------------------------------------------------------------------MASLAVSINQFAVEFSKKLAESAEG-----------------------------RNIFFSPWGISTSLAMVYLGTKGTTAAQMSQVLHFGSIQDFKFGPDSEKKRKMECHSGKSEEMQSDFQTLTAKILKHGNSYVLKIANRIYVEKTYLFHNKYLEDMKTYFGAEPQSVNFVEASGQIRKEINSWVGSQTGDKIPNLLPDDAVDNKTTMVLVNALYFKGTWEHQFSVQNTTERPFRIN--KTTSKPVQMMSMKQSLQVFHIEELQTIGVQLHYQNRE-FSLLLLLPEEVEGLKQLERAITYEKLDKWTS--ADMMD----TYEVRLYLPKFKMEESYDLQSALRDMGMTDAFNQGK--ANFSNMTSERNLFLSNVFHKTFLEINEEGTEAAAGTGSEVNFRIKAPSIELNADHPFLFLIRHNVTNTILFDGRFYSP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1K6-1", "uniprot_id": "SPB10_MOUSE", "id": "Q8K1K6-1", "name": "Serpin B10", "aln": "--------------------------------------------------------------------MASLAVSINQFALEFSKKLAESAEG-----------------------------RNIFFSPWGISTALAMLYLGTKGTTADQMAQVLQFSSVEDFKSCPDSEKKRKMEFNSGKFEEIQSDFQTLAAEILKPGNSYVLKTANRIYGEKTYPFHNKYLEDMKTYFGAEPQSVNFVEASGQIRKEINSWVGSQTGGKIPNLLPDDSVDTKTKMVLVNALYFKGTWEHQFSVKNTTERPFRVN--KTTSKPVQMMSMKQSLQVFHIEELQTIGLQLHYQNRD-LSLLLLLPEAIDGLEQLERAITYEKLDKWTS--ADMMD----TYEVQLYLPKFKMEESYDLKSALRGMGMTDVFSQSK--ADFSNMTSERNLFLSNVFHKTFLEINEEGTEAAAGTGSEISVRIKAPSIELNVDHPFLFFIRHNKTKSILFCGRFCSP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48595-1", "uniprot_id": "SPB10_HUMAN", "id": "P48595-1", "name": "Serpin B10", "aln": "--------------------------------------------------------------------MDSLATSINQFALELSKKLAESAQG-----------------------------KNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRIN--ETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRD-LSLLILLPEDINGLEQLEKAITYEKLNEWTS--ADMME----LYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSK--ADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWB4-1", "uniprot_id": "Q9VWB4_DROME", "id": "Q9VWB4-1", "name": "", "aln": "--------------------------------------------------------------------MKLGFLGLFGMVL------------------------------------------------------MIMFYEGAEGYTVNELRDVLGIYVDYPTLRRWYEDVRAYHYLNS----ENTKLFSLRYAYYDDVGDLELVKGYNSVVLEG-------VGEGNVVLREGRPRGVDFDQGASII---INDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNDGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHE-LVMIVLLPKSSQGVNLVLYQLKNLGLHRLLEKLEASKN----ETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLIAIGHRGACLTLYHQFARIVVDEEGLPNAVPQKS-----SGKNNIKFHVNRPFAYLVLQKKHKLLIHSGVFREGEIQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPH9-1", "uniprot_id": "Q9VPH9_DROME", "id": "Q9VPH9-1", "name": "", "aln": "--------------------------------------------------------------------MKLGFLGLFGMVLSLRAHICANTVDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYPTLRRWYEDVRAYHYLNS----ENTKLFSLRYAYYDDVGDLELVKGYNSVVLEG-------VGEGNVVLREGRPRGVDFDQGASII---INDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHE-LVMIVILPKPSQRVSLVLKQLKNLGLHRLLEELEASKN----ESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEFADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQKS-----SGTNNIKFHINRPFAYLVLQRTHKLLIHSGVFREGEIQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8C8-1", "uniprot_id": "SP77B_DROME", "id": "Q0E8C8-1", "name": "Serine protease inhibitor 77Ba", "aln": "MGKIADCLMLWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKAN---------------------------KDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYKVWSSFLNITT-------STIEVATLQAIYTGKGYPIKNN---------------YRDAIQNYNVQPMEVDFYSPDSVIQ--INEDTNRTTRGLIPYTILPQDVYG-AKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENT--ANLDRMSS--GLFAKLVVHSTKIIVDEQGTTAGAVTEAALAN--KATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNPKAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :.: : :.* *::* * :: . * : . . :. .. :* .. .* *:* . . * **. : * . . :. :. ***. *:. * * . * . .* *: : : ::: . ::* : :: : ::::**: :. : :. * . : :*.: :*** *:..: *: * .: : . . . : : : ::*:* .. : :: ::** ::: .. ::. * . . ", "identical_positions": 38, "similar_positions": 105, "identity": "7.48%" }, { "cls_id": "homologset.agr.MGI:2138735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69YW2-1", "uniprot_id": "STUM_HUMAN", "id": "Q69YW2-1", "name": "Protein stum homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPSHKDAETAAAAAAVAAADPRGASSSSG----------------------------------------VVVQVREKKGPLRAAIPYMPFPVAVICLFLNTFVPGLGTFVSAFTVLCG-----ARTDLPDRHVCCVFWLNIAAALIQILTAIVMVGWIMSIFWGMDMVILA------ISQGYKEQG------------------------IPQQL--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VBF8-1", "uniprot_id": "STUM_MOUSE", "id": "Q0VBF8-1", "name": "Protein stum homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLHKDAETAAAAAAVAAADPRGASSSSG----------------------------------------VVVQVREKKGPLRAAIPYMPFPVAVICLFLNTFVPGLGTFVSAFTVLCG-----ARTDLPDRHVCCVFWLNIAAALIQVLTAIVMVGWIMSIFWGMDMVILA------ISQGYKDQG------------------------IPQQL--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L5Y2-1", "uniprot_id": "A0ABK0L5Y2_RAT", "id": "A0ABK0L5Y2-1", "name": "Stum, mechanosensory transduction mediator homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLHKDAETAAAAAAVAAADPRGASSSSG----------------------------------------VVVQVREKKGPLRAAIPYMPFPVAVICLFLNTFVPGLGTFVSAFTVLCG-----ARTDLPDRHVCCVFWLNIAAALIQVLTAIVMVGWIMSIFWGMDMVILAKLKMTAVRKRRRRRGRRRKRRKRRRKKQMGKCLTTQSPCLHQELARLSLPPTQKTEREVTIVGSWEWLPGRARGALSSPGHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TYP8-1", "uniprot_id": "STUM_DANRE", "id": "Q5TYP8-1", "name": "Protein stum homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MD--QKDTEMNEKGVS---------SSTSG----------------------------------------VVVQVREKKGPLRAAIPYMPFPVAVICLFLNTFVPGLGTFVSAFTVLCG-----ARTDLPDRHMCCVFWLNIAAAFIQIVTAVVMVGWIMSIFWGMDMVILA--------KGYREQS------------------------VPQQL--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2E1-1", "uniprot_id": "STUM_DROME", "id": "Q9W2E1-1", "name": "Protein stum", "aln": "MQQTLSYSSSSPSPSPMPMPSASAAQTPPPNPNLTPNLNIRPSTNPIPRPRSTGGESAFQPAIIPVDYSYRTHTTRSILSAQSMAPSTFASNQSFVRQPSESDAQPYSSLFGDPVPPPLQPDDYFGTAAFETLRNGSVELPSSEEDALVAAMALNALIPAARERIFPSVPYSRTPRGSLLPYLQPPDIQILPNSSGGSSSEQLGSPNYRLLAPDDILNKPDVYDLENEVEEYTVVGQRMSFDDEEDEPTRTPSQAPAKLSVSSITTEDHRGLLSDSYSGRDWFRPAPQHFPEFTRIPRLRPSSKMIMSMKQDEGPLSPLATMIQDMNSSSSGGEERVAPNQSRPVSRDVVLSPKQYLEEQLGLERGSQRQSLEDYRMPPPPADPPPFRRTDLTEQDDSRSVEPEHSLKREMSPVIIRDSIPMGGDYRVEQPRPHKKTAFTILSTGQAASSAPRPPQQAPTRGRHASIQSTSTTTSSPAGRPQISPRRRSIFGSEPRLPELPSALGYTSHLVHQTTDDSPRPSVQFNMSGRHSRSKLAIPQKGILQQRDSLTSSIDTFTPRAQIRRGSIGRDPIRSLPYGQKIKSMETLPLINDQHRSSIPRLHYGSTMDLSRPEPAVFPPGALPRPLKPNLNPTRRQRGLLKIINKEESLTHNPPRSNWCSLDDLSRPSFDGTPNQARRRSSSTSPERRSSTQTVSDRRSSNLSSVTATTSDFSFRRPTLSTLPAAQTLSRMRRKSVQALSPNRIPNRIPSFGQRRQSIYQRDQEPKPLSRHGKIAKPSTLSPIIGTPNKDSSSAQSPNHRSSLMADAVDTPSEVSTRRDSVSRIPVRKSPDSRSSSPPKDFGIPASGRSSRASITRSPSRTMNAGSRSPSRSMHPSRTSSRESGRPGDSRSASRGPPSRPGSRLDQIGSRMDRPNSRLERSSSRAERSSSRADRPSSRFDVSNSRGNSRANSRLSINSSSLRSSSISPATMARNRSMRATTPSRRKSISLSPASAMMGRRKSISPDAVGQNRRVSSRGKPEPPEILSRRNSRSRIPTRSTKVASKSPPSSSKKRSKSPEKPKAMGSTPKSNKVGKGVTAKGSPKAKPKIAASAKPKTKTESLMKPPVKNANKTPVNGRPTTNAKKPASKAISTKDAKVEKGKETGKSVASKSNGKETESSVKSSKSQVTKTKPPGGTTSEAKKPATTKTHGITLEKGTNGTDPVGGIPPLAAQVGNAVLQAVEAVPAVTSEVTVPSTPGGKGAGGANMSKLVRMSSRMSLLSNKSTKVRSDSPQNRKVATVQEHATEKEETVGASSQPMSNDAAAILEKSQKTLENIQKTVTEATDEIHKTISENLTDLKSLENDLAADPSPTPSSGTTMARPGESASRTGTADGSIAPQSSGELPKSPFPPTQPIEASVSVLHPNESSAERIASVPEVECESSDLPTALDASESELVGNVMPTPESGADFKVDAKRRSPDGQGGSTAGSGGLAKSSSQEFLEDKDNVKKGGLCGCCSKLFMPCRRSRCSRCCRRRERNESAEDQPVLWSGNSSATTATNVQVIDETKPKRKKISDWLKSSCCRSCRKKPAIEEHEAHQEEVSKRTNQAANMSTGPRTRGKCGLCLSKVFCCRSVNRVDPTTGDETEMKQCCFCIPCRRGSRPNKKGSTVSWRDQDPELGIKPTESSVVEGASEAAMSAATDAGNDQVKEGCCKRFWLMLLCCRKRKRRESNARRQSIRAPPPSEDTRKKLHVDLVEYSSKMKGAIPVLPLYLAWFCAFCNVVFPGLGTLLSGLFCLCVGIPRFSQFDSARARIGSFIINIIVAVSQFFCVLFCFVGWGWSIWWGTIMLRCAKKLSKIKKVERLELEEEQ---------------------RQAQLAEAGKNGVAEADKT------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .... .: .. . : *:: * .. ::.*** :*: :* :* * *...*****::*.: ** :: * . :: ..: *.*. . . . :*** **:** *: * :* ", "identical_positions": 31, "similar_positions": 47, "identity": "1.62%" }, { "cls_id": "homologset.agr.MGI:2138741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q794E4-1", "uniprot_id": "HNRPF_RAT", "id": "Q794E4-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTRE-GRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP-----------GTARRYIGIVKQAGLDR------------MRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2X1-1", "uniprot_id": "HNRPF_MOUSE", "id": "Q9Z2X1-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTRE-GRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP-----------GTARRYIGIVKQAGLDR------------MRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52597-1", "uniprot_id": "HNRPF_HUMAN", "id": "P52597-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTRE-GRQSGEAFVELGSEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP-----------GTARRYIGIVKQAGLER------------MRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFJ8-1", "uniprot_id": "F1QFJ8_DANRE", "id": "F1QFJ8-1", "name": "", "aln": "------------------------------------------MADDEGFVVRVRGLPWSCSAEEVSRFFSGCKISSNGSAIHFTYTRE-GRPSGEAFVELESEDDLKIAVKKDRESMGHRYVEVFKSNNVEMDWVLKHTGPNCPETEGDGLVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQDIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYEPPRKGMGMQRPGPYDRPS----------GGGRGYNGMSRGGSFDR------------MRRG----GYGG-----GVSDG----------------------RYGDG-GNFQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYRATEPDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGSNGGYGGQMMGGMGN---QSSY-GHGGQQMGGGYTGGYSSQSSMGGYNDYNSQGGMSNSYYGGSRGSVGMNGMGGGWGM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH5-1", "uniprot_id": "Q9VGH5_DROME", "id": "Q9VGH5-1", "name": "", "aln": "MSNADVQFNYGQQGNGDNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISG----HGTAFVVKLRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKRATGAG--GGVGGRPGPYDIRDRGANRGGNDFGGGRNDWGNNGNFGVGANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIELFYDGKTRGLNG------------------------GEHGGGNGGGGMGNNGGGNFSRRI----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*::******.: ::: *:.. .: .. :.:*: :* *: :***:**: *::*:: * * :: ******:***.: * . .::: . .*:*****:. ::::* :*****:* .: ** : :* .*: ******** **: :*:** :::*:*******:*:** *:: . ****** * .* * .. *. * . ** * ..* ... ...* : :******* : * *:::**.*:.*..*:*: . .* :* **. * *:*:: .**.:.: :* **:*** :..: . ** . .* .* .:.. *.:. ", "identical_positions": 123, "similar_positions": 124, "identity": "19.1%" }, { "cls_id": "homologset.agr.MGI:2138811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62834-1", "uniprot_id": "CD123_RAT", "id": "Q62834-1", "name": "Translation initiation factor eIF2 assembly protein", "aln": "-------------MKKEHVSHCQFSAWYPLFRSLTIKSVILP-LPQNVKDYLLDDGTLVVSGREDPPTCSQPD-SGDEAEETQWSDDESTATLTAP------EFPEFNTQVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKSLSDIFLLFKSSDFITHDFTQPFIHCNDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKEHLQYKFLDEDFVFDIYRD-SRGKVWLIDFNPFGEVTDSLLFTWEELTSENNLRGDVSEADALEQDSPAFRCTNSEVTVQPSPYLSYGLPKDFVDLSTG-EDAHKLIDFLKLKRNQQEDD-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CII2-1", "uniprot_id": "CD123_MOUSE", "id": "Q8CII2-1", "name": "Translation initiation factor eIF2 assembly protein", "aln": "-------------MKKEHVSHCQFSAWYPLFRSLTIKSVILP-LPQNVKDYLLDDGTLVVSGREDPPTCSQSD-SGNEAEETQWSDDESTATLTAP------EFPEFNTQVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITHDFTQPFIHCTDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKEHLQYKFLDEDFVFDIYRD-SRGKVWLIDFNPFGEVTDSLLFTWEELTSENNLRGEVTEGDAQEQDSPAFRCTNSEVTVQPSPYLSFGLPKDFVDLSTG-EDAHKLIDFLKLKRNEQEDD-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75794-1", "uniprot_id": "CD123_HUMAN", "id": "O75794-1", "name": "Translation initiation factor eIF2 assembly protein", "aln": "-------------MKKEHVLHCQFSAWYPFFRGVTIKSVILP-LPQNVKDYLLDDGTLVVSGRDDPPTHSQPD-SDDEAEEIQWSDDENTATLTAP------EFPEFATKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEIRRCIQDFFKKHIQYKFLDEDFVFDIYRD-SRGKVWLIDFNPFGEVTDSLLFTWEELISENNLNGDFSEVDAQEQDSPAFRCTNSEVTVQPSPYLSYRLPKDFVDLSTG-EDAHKLIDFLKLKRNQQEDD-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC40-1", "uniprot_id": "CD123_DANRE", "id": "Q6PC40-1", "name": "Translation initiation factor eIF2 assembly protein", "aln": "-------------MKKEQVVNCQFSVWYPLFKKHTIKSLILP-IPQNVIDYLLDDGTLVVSGSENNNSQTQANNSDSDEEDIQWTDDETTTTVTAP------EFPEFNVKVQEAINVLGGCIFPKLNWSAPRDANWIALNSSLQCQSLSEIFLLFKSSDFITHDLTQPFLHCSDDSPDPTINYELVLRKWSELIPGGEFRCFVKENKLIAICQRDYTQHYQHIGKQEASISTSILQFFRDNIQYQFPDEDFVLDVYRD-SSGRVWLIDFNPFGEVTDSLLFTWEELTSGKNLTANQTQEETALPDGPAFRCTNSEVTVQPSPCLSYRIPRDFLDLTTG-EDAYKLIDFLKLKRGQQEEEEESNEEGEEPQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05791-1", "uniprot_id": "CD123_YEAST", "id": "Q05791-1", "name": "Translation initiation factor eIF2 assembly protein", "aln": "MSSQEYTTFIDIPVTRAQVEHCSYSFWSSLYPKYVPKSIVLKSLPKKFIQYLEQDGIKLPQEENSRSVYTEEIIRNEDNDYSDWEDDEDTATEFVQEVEPLIDFPELHQKLKDALNELG-AVAPKLNWSAPRDATWILPNNTMKCNEVNELYLLLNASNYIMHDLQRAFKGCVDGDDIKGLKFDLVLRQWCDMNPALEFRVFVKNAHIVGATQRDLN-YYDYLDELSDTFKDLIDEIVHDVVLPKFPDKSFVLDVYIPRPFNKIFIVDINPFARKTDSLLFSWNEIAAIAPPKNDVEDYELR------LVTRHNTGRFASKEHSENHVPQDLVEASLNPEAIRELTQKWKELLSQQAKEESSDSENET--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :* :*.:* * .:: . **::* :*::. :** :** : . :. :: ..: : :* *** *:* . :***: ::::*:* ** .: *********** ** *.:::*: :.:::**:::*::* :*: :.* * *.. ::::****:*.:: *. *** ***: :::. *** . :*:::.: . : * ::.:. : :* *:.**:*:* . .:::::*:***.. ******:*:*: : : : : : :. . .. . :*:*::: : . * :* : * .:* .: ", "identical_positions": 89, "similar_positions": 133, "identity": "24.05%" }, { "cls_id": "homologset.agr.MGI:2138828", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7DLY1-1", "uniprot_id": "F7DLY1_RAT", "id": "F7DLY1-1", "name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "aln": "----------------------------------MSQSANMSCCPGAANGSLGRSDGVPRMSAKDLFEQRKKYSNSNVIMHETSQYHVQHLATFIMDKSEAIATVDDAIRKLVQLSSKEKVWAQEVLLQVNDKSLRLLDVESQEELENFPLPTVQHSQTVLN---QLRYPSVLLLVCQDSDQNKPDIHFFHCDEVEADLVQEDIESALADYRLGKKMRPQTLKG--------------------------------------HQEKIRQRQSILPPPQSPAPIPFQRQPGDSPQAKNRVGLPLPASFSEPGYRRR-ESQDEEPRAVLAQRIEKETQILNCTLDDIEWFVARLQKAAEAFKQLNQRKKGKKKNKKGPAEGVLTLRARPPTEGEFVDCFQKTKLAINLLAKLQKHIQNPSAAELVHFLFGPLDLIINTCGG----PDLARSVSSPLLSTDAVSFLRGHLVPKEMTLWESLGETWMRPRSEWPREPQVPLYVPKFRSGWEPPLDVLQEAPWEIEGLTSVPSDQLNPKSRLSVRHSPKHSLSSEPQVPEDVAPPGSSPHANRGYHPTPAMTKYVKILYDFTARNANELSVLKDEVLEVLEDGRQWWKLRNRSGQAGYVPCNILAEARQED----VGAPLE-QSGQKYWG------PASPTHKLPPIFAGNKEELIHHMDE-VNDELMKKISHIKTQP-QRNFRVERSQPVHLPLT---FESGPEEVRAWLEAKAFSGRIVENLGILTGPQLFS------LNKEELKKVCGEEGSRVYSQLTVQKSFLEKQQSGSELEKLMNKIRRAEDSYSNVHTSPEAEGAPHL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K30-1", "uniprot_id": "ES8L2_MOUSE", "id": "Q99K30-1", "name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "aln": "----------------------------------MSQSASMSCCPGAANGSLGRSDGVPRMSAKDLFEQRKKYSNSNVIMHETSQYHVQHLATFIMDKSEAIASVDDAIRKLVQLSSKEKVWAQEVLLQVNDKSLRLLDVESQEELENFPLPTVQHSQTVLN---QLRYPSVLLLVCQDSDQNKPDIHFFHCDEVEAELVQEDIESALADYRLGKKMRPQTLKG--------------------------------------HQEKIRQRQSILPPPQSPAPIPFQRQPGDSPQAKNRVGLPLPVPFSEPGYRRR-ESQDEEPRAVLAQRIEKETQILNCTLDDIEWFVARLQKAAEAFKQLNQRKKGKKKNKKGPAEGVLTLRARPPSEGEFVDCFQKTKLAINLLAKLQKHIQNPSAAELVHFLFGPLDLIINTCGS----PDIARSVSSPLLSTDAVSFLRGHLVPKEMTLWESLGETWMRPRSEWPREPQVPLYVPKFRSGWEPPLDVLQEAPWEVEGLASVPSDQLTPKNRLSVRHSPKHSLSSESQAPEDIAPPGSSPHANRGYQPTPAMTKYVKILYDFTARNANELSVLKDEVLEVLEDGRQWWKLRNRSGQAGYVPCNILAEARQED----VGAPLE-QSGQKYWG------PASPTHKLPPIFAGNKEELIHHMDE-VNDELMKKISHIKTQP-QRNFRVERSQPVHLPLT---FESGPDEVRAWLEAKAFSARIVENLGILTGPQLFS------LNKEELKKVCGEEGSRVYSQLTVQKAFLEKQQSGSELEKLMSKIRRAEDSYTSQHTSPESEGAPHL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6S3-1", "uniprot_id": "ES8L2_HUMAN", "id": "Q9H6S3-1", "name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "aln": "----------------------------------MSQSGAVSCCPGATNGSLGRSDGVAKMSPKDLFEQRKKYSNSNVIMHETSQYHVQHLATFIMDKSEAITSVDDAIRKLVQLSSKEKIWTQEMLLQVNDQSLRLLDIESQEELEDFPLPTVQRSQTVLN---QLRYPSVLLLVCQDSEQSKPDVHFFHCDEVEAELVHEDIESALADCRLGKKMRPQTLKG--------------------------------------HQEKIRQRQSILPPPQGPAPIPFQHRGGDSPEAKNRVGP--QVPLSEPGFRRR-ESQ-EEPRAVLAQKIEKETQILNCALDDIEWFVARLQKAAEAFKQLNQRKKGKKKGKKAPAEGVLTLRARPPSEGEFIDCFQKIKLAINLLAKLQKHIQNPSAAELVHFLFGPLDLIVNTCSG----PDIARSVSCPLLSRDAVDFLRGHLVPKEMSLWESLGESWMRPRSEWPREPQVPLYVPKFHSGWEPPVDVLQEAPWEVEGLASAPIEEVSPVSRQSIRNSQKHSPTSEPTPPGDALPPVSSPHTHRGYQPTPAMAKYVKILYDFTARNANELSVLKDEVLEVLEDGRQWWKLRSRSGQAGYVPCNILGEARPED----AGAPFE-QAGQKYWG------PASPTHKLPPSFPGNKDELMQHMDE-VNDELIRKISNIRAQP-QRHFRVERSQPVSQPLT---YESGPDEVRAWLEAKAFSPRIVENLGILTGPQLFS------LNKEELKKVCGEEGVRVYSQLTMQKAFLEKQQSGSELEELMNKF----------HSMNQRRGEDS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TNY4-1", "uniprot_id": "A0AB32TNY4_DANRE", "id": "A0AB32TNY4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEPSNSDLQHVRIRYHFVARNANELTVQQGDELEVLENNQQWWLLRNRSGQSGYVPCNVLEEVKPEEQQYNRAALFSSQAVNPYKGTTTSPVPVNHAVVLEMNKSSRDKDNRDQQKE-VNDELLKRITDNKAQPPARNFRVERS-SRSIRIT---DESQPFEVHAWLNAKGFSRPVVECLGILNGAQLFS------LSKDELKAVCGDEGSRVYSQITVQKAQIERGNGDTELQEIMRRR------------QQEVDSTWD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPW1-1", "uniprot_id": "Q8IPW1_DROME", "id": "Q8IPW1-1", "name": "", "aln": "MFKLLSSSFKRRSFRRRSKPVPGLGDTMVNHHSNGGGSAGNSSGSLRGGGAHGGGGGGGDYSGDDRSGGGEERERLESDLHDKPTYLLEHLATFTVNKESGIVYPADGMRRLLQLEKTTGIWSQKMQLCLDYQWVLIMDYETGNIIERFPASLVQEPTAFTSNDAMELYNNILVFIVSGGGGSRSEMHIFQSQSVSAVHLVEDLKQLRSGKMITQQRGATPTQSGGGGASSMAMMMSKTSSSSSHSRVELHQHREQRAERERERDRDRERESHHHMHQRSSMEQYGIRAGVGVSGDDVAHISGETDSEHGGIGGGGATERDETSSTSSEKYERDVAVLNHCFDDIEKFIARLQHAAAASRELERRRRNRKSKKRDPGEGLLTLRTRPPHEKEFVDIFAKFKLSFNLLAKLKAHIHDPNAPELVHFLFTPLALIVEASSDTYYESQLPARVVNPLLTREAINLLINCVTSKETELWRSLGDAWVIPRDQWKDDVGS--YHPVFLDGWSPDYLIN-------DELEPPPNSPPAHVSKRRLEVQAGSGLNGRGGGGYDDYDSGNGMNMAMGIEKYTIHHGNDGLRERERERDRERAGAISASDFNARSELSFDSIEGRGGGAAGHGHGHGHGPGAGPTLSAITAGLQNLHTRESRSG---NGYGAGAGPGPSSELGGGGRGLPNVSDDQMLESWLEDLQATGAKIVLVTYPRTANNDKELSVMRGEYLEILDDTRKWWKARNMRGQVAHVPHTIVTPFNFGDGDGAQFYGQQQQPPTGPTGPGNKSRSGDNPGMEQRSPDPTDMMRSKHLG---------------KKGEFRYF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :. . . . ::. .: .* :*: : .. . :: : * .. . . .: : :. :. : :: : . : . :.: * :*: : :.. : . *. : :: : * * *: : . :: . ::: . . ", "identical_positions": 10, "similar_positions": 68, "identity": "1.2%" }, { "cls_id": "homologset.agr.MGI:2138853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AS37-1", "uniprot_id": "A2AS37_MOUSE", "id": "A2AS37-1", "name": "", "aln": "MVLIPSQAMGFWGTLLFLIFLEQSWGQEQTYIISTPIVFRVGAPENVTVQAHGHTEAFDTTVSVKSYPDENVRYSFSTVNLSPENKFQNTAILTIQAKQLSEGQNSFSNSYLEVVSKHFAKLEIVPIIYDNDSLFVQTDKSVYTPQQPVKVRVYSVNDDLEPATRETVLTFIDPEGSQVDTIEGNNLTGIASFPDFEIPSNPKHGRWTVKAKYREDASKTGTTYFEVKEYD--------------------KTYRISIMP---------------------------------------------------------------------------------------------------------------------------------------------TIDLQPEVEKQEAHGMCL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQPTECLRQKINEQASTYKHPMIKKCCYDGARYNIHETCVQRAARVKIGPICVKAFTLCCNMAHQILENSTFKHIHLS-SHSNHQAEHGDPQWRSQGKD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LN57-1", "uniprot_id": "A0ABK0LN57_RAT", "id": "A0ABK0LN57-1", "name": "", "aln": "MVLVPFQALGFWGTLLFLIFLEPSWEQEQTYIISTPIVFRVGAPENVTVQAYGYTEAFDTTISVKSYPNKNVNYSSGTVELSPENKFQNSAILTIQAQELSEEQNWFSNVYSEVVSKHFSKLEIMPIVYDNSSLFVHTDKPVYTPEQPVKVAVYSVDDDLEPVTRTTVLTF-DPEGSEVGIIGGRNGTGIASFPDFKIPSNPKLGRWTIKANYREDASTTGTTHFEVQGHE--------------------KAFKMAVMP---------------------------------------------------------------------------------------------------------------------------------------------TTDLQQKMEKQEAHVTC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQTSDCLVQKINEQASKYKHPVIKKCCYDGARYNEHETCVQRAAHVTIGPNCVKAFSLCCEIAHQM----TFKHIHMS-SLPNQWTERR-PQWRS-GRD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01031-1", "uniprot_id": "CO5_HUMAN", "id": "P01031-1", "name": "Complement C5", "aln": "--------MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSWVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANADDSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLVPRRKQLQFALPDSLTTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: * * ***** :* *****:**:* :*****.**:.:*.:*:*****:*:*:****:::. ** . *.**.******:******.::*. ** .* * *******:* : :** ***. **::***.****:*.*** ***::***:*..* ***** *****:*. : : ** *****:*****: * **:**:*:** *.***::***: : * :.::: . * *:: : .. :. :. * :**:* *:.***.::******** * .*** ****::.:** *:***: ** :* *: :.*.:::. : *: ** : ", "identical_positions": 172, "similar_positions": 98, "identity": "10.21%" }, { "cls_id": "homologset.agr.MGI:2138856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86YD5-1", "uniprot_id": "LRAD3_HUMAN", "id": "Q86YD5-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 3", "aln": "----MWLLG----------------------------PLCLLLS-----------SAAESQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHHCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSANSASSQAASSLLSVEDTSHSPGQPGPQEGTAEPRDSEPSQGTEEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AR95-1", "uniprot_id": "LRAD3_MOUSE", "id": "A2AR95-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 3", "aln": "----MWLLG----------------------------PLCLLLS-----------STAESQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCRNGLCIDKSFICDGQNNCQDNSDEESCESSLEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHHCNVTYNVNNGVQYVATQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSAYSASSQAASSLLSVEASSHNPEQPGSPEGSAEPRDSVPSQGTEEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LY78-1", "uniprot_id": "A0ABK0LY78_RAT", "id": "A0ABK0LY78-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 3", "aln": "MMRTKWLLEKYTGQMSEVLFNAHTTWKQSRVERLFRHVLGMLINKSPEKSSSGGEPAGESQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCRNGLCIDKSFICDGQNNCQDNSDEESCESSLEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHHCNVTYNVNNGVQYVATQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSAYSASSQAASSLLSVEGSSHSPEQPGPAESTSEPRDSVPSQGTEEV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** * :*:. .:.*********************************************************************************************************:***************************** ***************************************************************************************:****:******************************************************** ************** :**.* ***. *.::***** ********", "identical_positions": 320, "similar_positions": 15, "identity": "82.47%" }, { "cls_id": "homologset.agr.MGI:2138865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97839-1", "uniprot_id": "DLGP4_RAT", "id": "P97839-1", "name": "Disks large-associated protein 4", "aln": "MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSMEGTTGKVGGNGGKKGVLEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRS-GPASGLMTLGRQPERTQPRYFMHAYNTISGHMLKTTKNTTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRDMDSTAEGPIPCRRMRSGSYIKAMGDEDSDESGGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMPLPSKYPSWEEDYNPISDSLNDSGCISQVFGQASLIPQLFGHDQQVREADLSDQYEAACESACSEAESTAAEALDLSLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGITPGPEAPEPPPKHAALKSEHGTLTSSESHSEAVPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSAPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTSHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWMETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGICEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKAAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AZP2-1", "uniprot_id": "DLGP4_MOUSE", "id": "B1AZP2-1", "name": "Disks large-associated protein 4", "aln": "MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSMEGTAGKVGGNGSKKGGLEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRS-GPASGLMTLGRQQERTQPRYFMHAYNTISGHMLKTTKNTTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRDMDSTAEGPIPCRRMRSGSYIKAMGDEDSDESGGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEDDYNPISDSLNDSSCISQVFGQASLIPQLFGHDQQVREADLSDQYEAACESACSEAESTTAEALDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGITPGPEAPEPPPKHAALKSEQGTLTSSESHSEAIPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGIQVEDDWRSSAPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTSHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKAAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2H0-2", "uniprot_id": "DLGP4_HUMAN", "id": "Q9Y2H0-2", "name": "Disks large-associated protein 4", "aln": "MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGSKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGG-SPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************.*********************************************************************************************************************************:***:*******.*** :****************************************.***** ************ **:**********************.*****************************************************************************************: *::***************************** ***************************************** **** ****:**.*:*******.****:*************:******:*******************:**:***.****************************************************************************************************************************::*.****************:*********.** *********************************:*********.**********************************.*********************************************:******************************************************************************:**************************************************************************.**********.*******************************************", "identical_positions": 952, "similar_positions": 33, "identity": "95.87%" }, { "cls_id": "homologset.agr.MGI:2138890", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q49B93-1", "uniprot_id": "SC5AC_MOUSE", "id": "Q49B93-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------------------------MRVKNFEAWDYVVFAGLFVISSGIGVFFAIKERKKT------------------------TSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPAEVYRFGAS--FFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNH---VGGFNNVLEKAGNGSRLHIVD--------FDVDPLRRHTFWTITIGGTFTWLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLG-LWIIVACAVFSGLIMYSHFKDCDPWTSGVISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVK---SCFPH--LSDKLSTWISKGLCILFGIMCTSMAVVASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTG---ITLSFWVAIGSFIYPAPESKTLP-LPLSTEHC----------------------VELNITTTVAPQISS-RPVLADTWYSLSYLYFSAVG-CLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLFCFWSKKYKTLCWCGVQHDRETEQDYLDSGSAWKQGVESGLQNGLKQDTLAQIPGYNPKEKSYSNSVPEKTTYF-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARH5-1", "uniprot_id": "A0A8I6ARH5_RAT", "id": "A0A8I6ARH5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MAVKSFEAWDYVVFAALFVISSGIGVFFAIKERKKT------------------------TSREFLVGGRQMSFAPVALSLTASFMSAVTVLGTPAEVYRFGAS--FLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYILQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNH---VGGFDNVLEQARNGSRLDIVD--------FDVDPLRRHTFWTIAVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLG-LWIIVVCAVFCGLIMYAYYKDCDPWTSGAILAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVK---SCFPH--LSDTLSTWISKGLCLLFGIICTSMAVLASLMGSVVQ-----------------------------GALGGLLTG---ITLSFWVGIGAFVYPAPDSKTLP-LPLSTEFC----------------------VQQNKTTTEAYQLSS-RPVLADTWYSLSYLYFSAVG-CLGCIAAGIIISFLTGRQRGKDVDPLLIRPVCNLFCFWSKKYKTLCWCGVRHDQETEQDYLDSGSAWKQGVESGLQNGLKQDTLSQIPAYNPKDKSYPKSVQEKTTYF-------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1EHB4-1", "uniprot_id": "SC5AC_HUMAN", "id": "Q1EHB4-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------------------------MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKA------------------------TSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGTPSEVYRFGAS--FLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTH---AGGFHNVLEQSTNGSRLHIFD--------FDVDPLRRHTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLG-LWIILVCAVFSGLIMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFEDFVK---SCFPH--LSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTG---ITLSFWVAIGAFIYPAPASKTWP-LPLSTDQC----------------------IKSNVTATGPPVLSS-RPGIADTWYSISYLYYSAVG-CLGCIVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPGYDPKDKSYNNMAFETTHF--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T384-1", "uniprot_id": "SC5AC_DANRE", "id": "Q7T384-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------METVGRFQAGDYVVFACLFVVSSGIGVFFAIKERNKA------------------------PSKEFLVGGRQMSCGPVALSLTASFMSAVTVIGAPADVYRFGAS--YVIFGVAYTFVVFFTAELFLPVFYRSGITSTYEYLELRFCKLVRVAATLIYIIQTILYTGVVVYAPALALNQVTGFDLWGSIFATGIVCTFYCTLGGLKAVVWTDAFQMVVMVVGFLTVLIQGSSR---AGGIENVWSTSRTGGRLQVFD--------FDVSPLRRHTFWTLSVGGTFTWLGIYGVNQSTIQRCISCKTEGHARWALYLNLLG-LWIILFCAVVSGLIMYSYYSHCDPWSSGLISAPDQLMPYFVMEILGAFPGLPGLFVACAFSGTLSTVAASINALATVMYEDFVS---QCFPD--LSNRAASWISKALCVAFGVACTTMAVAASYMGGIVQAALSIHGMCGGPVLGLFSLGILFPFTNLKGAVGGLIVG---ISLSFWVGVGAFIYPAPSNNTHA-LELNTAGCNI------------------TAAAFEPTSATVTQLTSDRNWLADSWYSMSYLYYSAVG-FIGTVAAGLLITLLTGPMDPKLLKPGMTRSVKEVMCFCTEKFTEADLG------EGKEDVGDFGKAWEKHPDQGCT--LRMDEKFRCSCDNQQENGNTNAGFDHNETSIVQKKL-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P83740-1", "uniprot_id": "SC5A6_DROME", "id": "P83740-1", "name": "Putative sodium-dependent multivitamin transporter", "aln": "--------------------------------------------------------------------------------------------------MATLGAWDYTILAVVLIISVAIGIYYRFVGGKQS------------------------TTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSMENYQYGTM--FVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIICAWVK---AGSLEVIWRVAQENGRINLTN--------FSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVKSLSAARAALWWCLPI-LCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLIS---LAFCFWIGFG-----QPKPPLVS-LDMSTAGCP-------------------VDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWYAALG-FLITFFGGWLLSWLFALLKWDNNR----RIYQDADCTLIKHDLFVPPIAKRLQRRQMPLLVVTGTSSEIG-------GITTESATAPPRLDEIEWEKHKAVA-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91659-1", "uniprot_id": "P91659_DROME", "id": "P91659-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------MSTTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKN------------------------TTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSIPAESYTYGFN--YIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIR---SGGMFTVMERASDGGRFNFD---------FGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLG-FLIISFFNTISGIIMFARYYGCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKP----RIR--HTEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVS---VVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPV--TMKPPSGAP--VTTAFHSDRDFSLYDISFYWYKVLG-SALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKFLSLPVTDQDLEEVPLRGSKVAATPDLRIEPTEKEKQTVTEP---------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9U2-1", "uniprot_id": "Q9V9U2_DROME", "id": "Q9V9U2-1", "name": "", "aln": "-----------------------------------------------------------------------------MASSVSNLASTVATATTATLEDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKN------------------------TTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFN--MIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVLVAILGTSN---TGGITNVLENAAEGGRFDFS---------FGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAGVG-FLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKP----RIN--HSEAKANATMKLVIVVMGAYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFS---CLVMLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLG-ALLVFAWAIPMSYVWPLDKEEKQNPKLYSPFVRSMLNKPSPVLELEELPLK------TPLSEEQIKEKENGSATEA---------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9U1-1", "uniprot_id": "Q9V9U1_DROME", "id": "Q9V9U1-1", "name": "", "aln": "------------------------------------------------------------------------------MSSLLNATVLATAATVVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGED------------------------TTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIPAEMYAYGIN--WVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVGVLGAHR---VGGFFEVLRIAGEGGRLDIN---------YNFDLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFG-FILIMFFNCFTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKP----HIR--HTEHRANVIMKLFVFFTGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGVLAS---IACMATIVI-----LSWGRNHYDTLPTSTSACPAS-LNGTIKDIS---------TASPLFLGS--TTEAPVGEKEFSILDLSFNWYTVTG-FVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPFVHYKLTPSD-EPHQLN-----------LEKPEKV----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3R0-1", "uniprot_id": "Q9W3R0_DROME", "id": "Q9W3R0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------MHVEELRASLQSFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANG---SEEAASSAA--------SYLVGGRQMKIFPITMSLISSFISGITLLGTPTEVYLYGAQ--YMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRYNRSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQTLIMFGAMALVLIKGTLD---IGGPGVVWQKAQETARLEVPN--------FSADLSERYTFYSLVLGGVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAG-VLAFLMICGYTGLLIYATYSQCDPLETKLAQRNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKT----FRKSPLTEGQTAFVMRSVVVVFGIIFVALVFAVEKLGAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLGGFSS---LIVMAWMCVSAQRDLVTGDLVYKRKPYSTMGCNYTFAGEPR----------------EFASLALDGAISSVPSAPFQLYRISYLYFTLFG-ALVTIVVALVTSLLLRETDLDGVDTRLLTPFVRRWLER--RRHRRSKIPDSGQK-------SSNKQETKT---------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGP3-1", "uniprot_id": "Q9VGP3_DROME", "id": "Q9VGP3-1", "name": "", "aln": "----------------------------------------------------------------------------------------MSNIEEVLGELQRFAWPDYVAFVSMFLLCIGIGIYFGFMN-----------------KSVSED--------DYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVYSYGIQ--YLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGSVMFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLGALCLVAIKGTRD---IGGAGVVLERAWSSDRLEAPD--------LSIDPTVRHTFWCLFFGGIVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVG-VLILMALCGYNGLLIYATYQNCDPLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKP----YVKKPLSSSAINWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSALVGGVMG---VIAMSWVSLNAQWAIASGAITYKTKPLNVEQCDYSFN--------------------VTTSLANTTHLGASAEDIFPLYRISYMWYTTFG-ASITIFVALLGTFVFGKNNPNKVDPVLLTPCIRKFFAFGSEKHMDAFRPDIPLQ-------HKLRNDEVAL--------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBK1-1", "uniprot_id": "Q9VBK1_DROME", "id": "Q9VBK1-1", "name": "", "aln": "MSTTADPVALGVNSPVEDVVAKTTTTVANAIAKTVAVISSTVSTSSTTGATSTISTSSSTPTTSTTFAYTPTPTPTQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGK---DGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQ--YAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRFDRRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLD---LGGLSVVLDHNRQYDRLVGPD--------MTFDPTARMGVFALFVGGALFKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIG-FMFVMLMCVYIGLLAFAEFYHCDPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEP----FRKKPLTERQTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTGISCA---SSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTFD--------------------LPANWNATTTATPTESTSHGIHEISFLWYTAVG-SVGTVLGSLLATLYFGRQDPRVVDKELISPVLRKFWYGKYESVASEEKNNFNLH-------ESETQLKLEQP-------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPY0-1", "uniprot_id": "Q8IPY0_DROME", "id": "Q8IPY0-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------------------------MDTYRFGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTP--TNEAPERRHQNFGSKKMNDYMMGSRNLRVFPVGMSLIASCISAVAIIGTPSEIYNYGTQ--YCFIVIALVLQGLAVSYIYLPVFSALQVTSSYEYLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCY---IDDQADFLEGLVRGGRLIFSE--------TNPSPFARHTVWSVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVG-AAFFISLLCYLGLLIFHAYRDCDPLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRG----CFKMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASSTFGIFTVGMLVPWANTVGTAVGGIAS---VLLTGWISFGSQFAAASGQLGSQRLPVSVEGC--------------------------LANASVAENAWVAEEEVFPLYRLSYHWISPIG-VLTVVVVGSLVSLVTKPTDIKSLDSDLITPVIHRFLPKECFEQG-----NAEEN-------SVKDNPLLF---------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ85-1", "uniprot_id": "Q9VQ85_DROME", "id": "Q9VQ85-1", "name": "Sodium-coupled monocarboxylate transporter 1", "aln": "------------------------------------------------------------------------------------------------MDTYRFGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSP----ADTPEISIPNFGSKKMNEYLMGSGHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQ--YSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCY---ITDLDDFFESLVDGGRLIFGN--------INPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLG-SIIFYSVLSFLGLLIFNMYKDCDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRG----CFKMQPGETASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAG---FLLTGWITFGSQIAAASGQLHHHRLPVSVASC--------------------------PGNVTARENVWVDEEQVFPLFRLSFHWINPIG-ALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQR-----NLDKS-------EATDIYTIT---------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLR8-1", "uniprot_id": "Q9VLR8_DROME", "id": "Q9VLR8-1", "name": "", "aln": "----------------------------------------------------------------------------------------MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQ--YWFIAIAIMLQGIAVSYVYIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVY---ANGLNVLFDDAAKGGRLIFNN--------TNPSPYVRHTVWSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIG-VAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRG----CFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVGGIAS---ALLAGWISFGTQFTIAAGELNSQKLPVSVEGC--------------------------VGNVTLRENIWVDEEQVFPLYRLSYHWINPIG-VATVIVVGALVSLVTKPTNMKTLDPDLISPVIHRFLPKECFSGR-----NLHAQ-------AHKNLLNVS---------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IN99-1", "uniprot_id": "Q8IN99_DROME", "id": "Q8IN99-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------------------------MDNYRFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSE-------DNRRTNFGSEKIDEYLMGSRNMKVIPVSITLYR----VTSIIGTPSEIYHYGTQ--YYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLRFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMGGLKAVVHTDVWQVAVMFLSLVAVAFLAIYY---SNGLVAVFDDAEQGGRLMLAN--------TNPSPYVRHTVWSVLIGGFSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIG-VSIFIALCCFMGLLLFSKYKDCDPRSAGMILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRG----FFKMEPSERQSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSS---VLLAGWISFGSQIAAASGQLKSGMLPVSVKEC--------------------------VGNVTLPEDPWVDQDQVFPLYRLSYHWVSPIG-VVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECFRGR-----NLNER-------TEESLIQ-----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33413-1", "uniprot_id": "DUR3_YEAST", "id": "P33413-1", "name": "Urea active transporter", "aln": "---------------------------------------------------------------------------------------------MGEFKPPLPQGAGYAIVLGLGAVFAGMMVLTTYLLKRYQK--------------------EIITAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACFQIIAFAILAIKTKQMAPNAHTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDVLGSPGKVYDLVREAAKRHPVDGNYQGEYMTMTSKSAGILLIINLIGNFGTVFLDNGYWNKAISASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTYPDPLTSFQANSGLVLPAAAIAIMGKGGAVASLLM--IFMAVTSAMSAELIAVSSVFTYDIYRE----YIDPRASGKKLIYTSHVACIFFGLAMSGFSVGLYYGGISMGYIYEMMGIIISSAVLPVVLTLCSKDMNLVAAVVSPILGTGLAIMSWLVCTKSLYKELTVDTTFMDYPMLTGNLVALLSPAIFIPILTYVFK-----PQNFDWEKMKDITRVDETAELVQADPDIQLYDAEANDKEQEEETNSLVSDSEKNDVRVNNEKLIEPNLGVVISNAIFQEDDTQLQNELDEEQRELARGLKIAYFLCVFFALAFLVVWPMPMYGSKYIFSKKFFTGWVVVMIIWLFFSAFAVCIYPLWEGRHGIYTTLRGLYWDLSGQTYKLREWQNSNPQDLHVVTSQISARAHRQSSHFGQVDEII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . : . .: .. : : :: ::: . . * * . . : . *: : . . : : :* . * .**:*... ** : :. . . . . . : . . . : : : . .: : . ::* .. .: .::: * . *::: : : . * * : . * : . . : . . ", "identical_positions": 17, "similar_positions": 79, "identity": "1.98%" }, { "cls_id": "homologset.agr.MGI:2138893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZL57-1", "uniprot_id": "D3ZL57_RAT", "id": "D3ZL57-1", "name": "USP6 N-terminal-like protein", "aln": "------------------------MNSDQDVALKLAQERAEIVAKYDRGRE-GAEIEPWEDADYLVYKVTDRFGFLHEEELPYPNAAADRQK-QLEIERTSKWLKMLKRWERYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFRLNLRIWDIYIFEGERILTAMSYTILKLHRKHLMKLS-MEELVEFLQETLAKDFFFEDDFVIEQLQVSMTELKRAKLDLPEPGKEDEYPRKPLGQLPP-------EYTNHLSNGQRSVGRPSPKISSRREDGSPHKAHEHSPAHHSRNGTPERVGQSRR-KSVDEGSKNLKQEADFQRKPSSGTQD--NSKHYNHATANQNSNALSNIRKEFVPKWRKPSEASAIERTAKYAIEG-RSHSVFPALSVAVPSSAETRLSNSRQKMKAFDGGEGNRGSNASQYDNVPGSESEPGASAEEGPERTH---------PHSPRKHSEPSPSPSKVPNKFTFKVQPPSHVRYPSQPAGEDHRAAYPPSYSNPPVYHGNSPKHIPTAHSGFASTQISLGPQVNPSRRPYGSSLSGDTSPEKSYGRLTP-VLPSSRIEVLPIDIGARGY-GSSGSPKSGKFILPPVDYLPENRKWSEFSYTYRPEVHGQSWTQDATRS---HLSNLPKYTAFP------HIPLQDHGLPEVSVDSPVRYKTSPAVEEASPPGYPYAGPTPSAHHYRNREGLSVQESVLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XC3-1", "uniprot_id": "US6NL_MOUSE", "id": "Q80XC3-1", "name": "USP6 N-terminal-like protein", "aln": "------------------------MNSDQDVALKLAQERAEIVAKYDRGRE-GAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAADRQK-QLEIERTSKWLKMLKKWERYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFRLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLS-MEELVEFLQETLAKDFFFEDDFVIEQLQVSMAELKRAKLDLPEPGKEDEYPKKPLGQLPPE-----SACVNHLSNGQRSVGRPSPKTSSRREDGSPRKNHEHSPVHHSRNGTPERAGQSRR-KSVDEGSKNLKHEAESQRKPSPGMQD--SSRHYNHAAANQNSNAISNVRKEFMPKWRKPSDASAIERTTKYAVEG-KSHSALPALPVAIPGSAETRLPNSRQKMKALDGGEGKRGSNASQYDNVPGGESEHGASAEEGPERTH---------PHSPRKHPEPSPSPPKVPNKFTFKVQPPSHVRYPPQLPEEDHRAAYPPSYSNPPVYHGNSPKHVPTAHSGFVSTQISPRPQINPSRRPYGSSLSVDTSPEKAYSRPTPVVLPSSRIEVLPIDMGARGY-GSSGSPKNGQFILPPVDYLPENRKWSEVSYTYRPEMHGQSWTRDAHRS---HLSNLPNYAAFQ------HIPFQAHGLPEVSVDSPVRYKMSAAVEDASPPGYPYAGPSPSAHHYRNGEGLSVQESVLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92738-1", "uniprot_id": "US6NL_HUMAN", "id": "Q92738-1", "name": "USP6 N-terminal-like protein", "aln": "------------------------MNSDQDVALKLAQERAEIVAKYDRGRE-GAEIEPWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQK-HLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLS-MEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPEL---QSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRR-KSVEEESKKLKDEADFQRKLPSGPQD--SSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEG-KGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASR------GNLPKYSAFQ------LAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BC35-1", "uniprot_id": "A0A8M2BC35_DANRE", "id": "A0A8M2BC35-1", "name": "USP6 N-terminal-like protein", "aln": "MQVLQIVKELVSPSRRRAGSRFTASDSEQDAAVKLEQERAEILAKYDKGKE-KAEVEPWEETNFELYKAVDRFGFLHEGELVYD-IVEEKQK-QLEVERTTKWLKMLKSWEKYKNSDKLVRRIYKGIPLQLRGQVWCLLLDIPKIKEEKKDFYEKLKIRARGLSPDVRQIDLDVNRTYRNHIMFMHRYDVKQQDLFHVLTAYSVYNTEVGYCQGMSQITALLLIYMNEEDAFWALVKLLSGQRHTMHGFFVPGFPKLMRFQEHHDRILQKMMPKLKQHLDNQEVYTSLYTMKWFFQCFLDRTPFTLTLRIWDIYILEGERVLTAMSYTILKLHKKTLLKLS-MEELVKFLQVTLSNDFFFEDDFVIEQLQNSMSELRRSKLELPPPGKEDEYPKKPLGQLPPEPPGLAAAATNHVANGQ-PVGQTGEGLPPRGPSPAVSVNKRVDSGP-VTDGTPERYQDSRPPSSLDKFHHPDKIERDGRGVYANKERVPVGGKASTQNQANHNSNARSSMRREIGPRWVKPSEGKLEAVKAAALRESQLSLATGVPPSPSSPTPDEATGAQRRPRSRAFAPG-SNRASNASQYDNVPGPDGEVMEIIELEKPPSRPPSRP---FVGPPLRQGSPTRPPSGGTGVSPFRVPKQSMMQSKPEPRAP---LHYPPGMT--PVYTPYISETRQEER--LYSQSYTEQIYATTGRG------SSNPSPEKTVMNNSYLTYRRPPPDMPPLRVAPAELSSQIDSAGEGVYYLRQPTRLIGSPAYPPTELRYEGNRRREGWYGDVEAGPPRSPAGVPRSPSFQKAQLSPVHPVQEFNFAQANISDAVLHFRGPYQEHSGRQQLPP--LFGGAHYRQAQEAFAMQESMLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9K4-1", "uniprot_id": "A1Z9K4_DROME", "id": "A1Z9K4-1", "name": "", "aln": "---------------------MTDGEQQEALVKRAEDEREDIFRRYELGLDPSNVVDSWENPTFEIYHRTDKYGFLHDSRLPSTRDAQEVHRNKIEMERDKKWMKMLNQWPPPQ--DKLHKRVYKGIPDRVRMVAWNKLLDIQQSINNNAGVYLRMLQLARKYSTETRQIDADVNRQFRDNLAFRERYSVKQCSLFNVLNAYSIYNSELGYCQGMACVAGVLLLYLHEEEAFWALNTLITDQKYGMHGLFIEGFPKLTRFIDHHDRIMSKIMRKLHKHFTKHNVDALLYAIKWFFVVFVERVPFSLSLRVWDIFMLDGDRVILSMAITILYLHKDELLRLKDMDAIIEYLQVRLHKNFGYSDDDAIQALERVMKKLKDLKLDVPPPAKSNEFPTRKLG-----------------------------------------------------------------------------------------------------------DFVEADMEKKIGRRRNDYTDAEKQVITDVISRQEQNAIDVQSTVSYETSECATGDGYSMKTFESITSLATSPANSSYSLYSNG--------------------------------------------------FVVTTIDSEQDPAR------------------------------------------------------------------SQSIHNLSYLQTHPALPPNGLQHMRHSFSSDSDSRNRIDLDQALEVLQRQ--------------------------------------------------------QLPLHPKTPSSQVVYIVQNGGGGGRYMDGHRDAADDDDDDALSVENTRL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:: . : :** :*. :*: * : ::.**:. : :*: .*::****: .* . : :: ::*:** .**:***: * : :*: :*:***** ::* .* **:* : ::. ..* :: ** *.: **** **** :*::: * .**.*** .**:** ***:**:*:******: ::.:**:*::**:***** .*::. :: ***:*: ***** ** :**::*:.*:: **::*: .::: : :*::**** *::*.** *.**:***::::*:*:: :*: *** **:. *::*. *: :::::* * ::* :.** .*: *: * :*: **::* *.*.:*:* : ** . . :.:.::: : . :: . . : . . . . . . : . *. * *.* * * . : .. . : * . .* . : : : . . . * :.:::::: * ", "identical_positions": 153, "similar_positions": 190, "identity": "17.51%" }, { "cls_id": "homologset.agr.MGI:2138915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64122-1", "uniprot_id": "MYL9_RAT", "id": "Q64122-1", "name": "Myosin regulatory light polypeptide 9", "aln": "MSSKRAKAK--TTKKRPQSATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEXLEGMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYRER-IDKKGNFNYVEFTRILKHGAKDKDD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ19-1", "uniprot_id": "MYL9_MOUSE", "id": "Q9CQ19-1", "name": "Myosin regulatory light polypeptide 9", "aln": "MSSKRAKAK--TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24844-1", "uniprot_id": "MYL9_HUMAN", "id": "P24844-1", "name": "Myosin regulatory light polypeptide 9", "aln": "MSSKRAKAK--TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40423-1", "uniprot_id": "SQH_DROME", "id": "P40423-1", "name": "Myosin regulatory light chain sqh", "aln": "MSSRKTAGRRATTKKRAQRATSNVFAMFDQAQIAEFKEAFNMIDQNRDGFVEKEDLHDMLASLGKNPTDDYLDGMMNEAPGPINFTMFLTLFGERLQGTDPEDVIKNAFGCFDEENMGVLPEDRLRELLTTMGDRFTDEDVDEMYREAPIKN-GLFDYLEFTRILKHGAKDKDEQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::: .: *****.* ***********:** ****************::*****************: *:***.*************:***:*:********:***.***** *.: **:***************:******* *.: * *:*:**************: ", "identical_positions": 135, "similar_positions": 26, "identity": "77.14%" }, { "cls_id": "homologset.agr.MGI:2138934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWQ8-1", "uniprot_id": "A0A1B0GWQ8_RAT", "id": "A0A1B0GWQ8-1", "name": "Methyl-CpG-binding domain protein 5", "aln": "MNGGKECDGGDKEGGLPAIQVPVGWQRRVD----HNGVLYISPSGSLLSCLDQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADDDVTKLCTHKRKIIAVATLHQSMEAPHPSLVLTSPGGGTN-AAPAVPSRAATPRSARNKAHEGITNSIMPECKNPFKLVAGSSNAMGRLYMQDLPGSQQQELHTVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRNNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSAN---MEIPRAMFHHKTPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPIIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRIQHSTSTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQASCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGMSNVLNTPSSAAFPTAP--AGNGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSNSSGAVASSGNTEGHSTLNTMFPP--TANMLLPTGEGQSGRAALRDKLMS--QQKDSLRKRKQPPTTVLSLLRQSQMDSSAAPKPAPDLLRKHGQGSFPISSMSQLLQSMSCQS-SHLSSNSTPGCGGSNTALPCSANQLHFPDPNMN----STVLQNSLTQSIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSR---ISTSSTPVIPNS------IVSSYNQTSSEAGGSSLPSSIAIAGSSHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVG--QEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGFLNPNVNAALAFLSGDVDGQVLQPVHFQLLAALLQNQARAAAMLPLPSFNLTISDLLQQQNTPLPLLTQMTAPPDRLPSNQSDNSRADTLLGSPLGNPLTGSDTTFNPLLLPAVTGASGLMALNPQLLGGVLNSASANTAIHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVVSMAETLLNISNNAGNPPGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINSSLNNHQLTHLQSLLNSSQMFPPSQQQPPPQPHLLQGQQNLQAFQGQPTVLCPANNNPMACLFQNFQVRMQGDAALLNKRINSQPGLTALPEN----PNLALPHFQDTPCELQPRIDPSLGQPMKDG--LVMGGQGDAS-VDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIG-DPLNLSSAVSAVIHGRNMGGADHDSRLRNARGARLP-KNIDHGKNSGEGDGFECYKSASCHTSRKQWDGEQSPRGERNRWKYEEFLDHPGHIHNSPCHERPNNVS-------TLPFLAGEQHPILLPPRN-CQGDKILEENFRYNNYKRTMMSFKERLESTVERCTHINGNRPRQSRGFGELLG-TAKQDLVLEGQSPGSSNSLES------------------------------SLVKDYIHYNGDFNAKSINGCVPSPSDAKSISSEDDLRNPDSPSSHELIHYRPRTFNVGDLVWG--QIKGLTSWPGKFIREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKRSRKSGKLNNHLEAAIHEAMSELDKMSGT--------VHQIPQGDRQMRPPKPKRRKISR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AYB6-1", "uniprot_id": "MBD5_MOUSE", "id": "B1AYB6-1", "name": "Methyl-CpG-binding domain protein 5", "aln": "MNGGKECDGGDKEGGLAAIQVPVGWQRRVD----HNGVLYISPSGSLLSCLDQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADDDVTKLCIHKRKIIAVATLHQSMEAPHPSLVLTSPGGGTN-ATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMTGSSNAMGRLYMQDLPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRNNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTN---MEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPIIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRIQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQATCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGMSNVLNTPSSAAFPTAP--AGNGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSNNSGAVASSGNTEGHSTLNTMFPP--TANMLLPTGEGQSGRAALRDKLMS--QQKDSLRKRKQPPTTVLSLLRQSQMDSSAAPKPGPDLLRKHGQGSFPISSMSQLLQSMSCQS-SHLSSNSTPGCGGSNTALPCSANQLHFPDPNMN----STVLQNSLTQSIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSR---ISTSSTPVIPNS------IVSSYNQTSSEAGGSSLPSSIAIAGSNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVG--QEHALHFPSNSTANNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DISSINNSLNNHQLTHLQSLLNSNQMFPPNQQ---PQQHLLQGHQNLQAFQGQPTVPCPANNNPMACLFQNFQVRMQGDAALLNKRISTQPGLTTLPEN----PNLALPHFQDTPCELQPRID--LGQPMKDG--LVMGGQGDAS-VDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIG-DPLNLSSAVSAVIHGRNMGGVDHDGRLRNARGARLP-KNIDHGKNSSEGDGFECFKSASCHTSRKQWDGEQSPRGERNRWKYEEFLDHPGHIHSSPCHERPNNVS-------TLPFLAGEQHPILLPPRN-CQGDKILEENFRYNNYKRTMMSFKERLESTVERCTHINGNRPRQSRGFGELLG-TAKQDLVLEGQSPGSSNSLES------------------------------SLVKDYIHYNGDFNAKTINGCVPSPSDAKSISSEDDLRNPDSPSSHELIHYRPRTFNVGDLVWG--QIKGLTSWPGKFIREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKRSRKSGKLNNHLEAAIHEAMSELDKMSGT--------VHQIPQGDRQMRPPKPKRRKISR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P267-1", "uniprot_id": "MBD5_HUMAN", "id": "Q9P267-1", "name": "Methyl-CpG-binding domain protein 5", "aln": "MNGGKECDGGDKEGGLPAIQVPVGWQRRVD----QNGVLYVSPSGSLLSCLEQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPHPSLVLTSPGGGTN-ATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGRLYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTN---MEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAAFPTAS--AGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSSNSGAVAGSGNTEGHSTLNTMFPP--TANMLLPTGEGQSGRAALRDKLMS--QQKDALRKRKQPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQS-SHLSSNSTPGCGASNTALPCSANQLHFTDPSMN----SSVLQN-----IPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSR---ISTSSTPVIPNS------IVSSYNQTSSEAGGSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVG--QEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMSSINNTLSNHQLTHLQSLLNNNQMFPPNQQ----QQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAALLNKRISTQPGLTALPEN----PNTTLPPFQDTPCELQPRIDPSLGQQVKDG--LVVGGPGDAS-VDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIG-DPLNLSSAVSAVIHGRNMGGVDHDGRLRNSRGARLP-KNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGERNRWKYEEFLDHPGHIHSSPCHERPNNVS-------TLPFLPGEQHPILLPPRN-CPGDKILEENFRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLS-TAKQDLVLEEQSPSSSNSLEN------------------------------SLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTFNVGDLVWG--QIKGLTSWPGKLVREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGT--------VHQIPQGDRQMRPPKPKRRKISR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JR92-1", "uniprot_id": "MBD56_DROME", "id": "A8JR92-1", "name": "Methyl-CpG-binding domain protein 5/6 homolog sba", "aln": "MAAASAGQQQQQHQHQHKLNIAGSAETVVSGMQHQQQHQQQHQQINMFKQQQQMLPLQQQHHQFFQQQQTKFVSRVVTSAAVHQQQQQHHHQQQQQQQHQQQQQILPAGLVNGNGSGNMMQVANLHLQQQQQQRNSQQHIFVCPTSNQQLLLQQQQQQQQQQQQQQTKQRQAQIKLPIKSAATTGVTAATVAAATAATGATHCMSTTIAARQMSQNNQLYAKNVAKANNASSNGNINRKTATSYNGNLAPGWRRLTNNNEVAYISPSG---KTLRTQFQIKDYLLTQGTCKCGLPCPLRPEYLFDFNAQVPNQPLKLPTEASTATPTPCRHQRRFLESQQLQLPQQQQQQQHLQHQQQQQQAVKDVSVDVAVSVSGPAAVSDVFSTLMTSTARTATMVTPTAATSPAQAATTTTHEMANKDADCHKYGNNKLPATNRTATTPTPAPTPPPQHPNGMPTSQALALGGVPVGVHPKRPTGGHVIKQP------ASVLGPPCTPPLAVGGANTVIQQQ--QPLQQHPNFKDDPAGYLQQQTALLHNSLGVGLDATKTAAGTSTARALPQEPIVHSSQQQQQQQQQQLQQQQQLQRQKIRRLSLFGKWETDPAPATNSQPTNGTRALQVDAAAFARPQKPQVTCVTLVPPPQESPVSSSAAETLEKRPEQVGAISTSHESPRQSLSSPTDSVDSAKSTPSASPKPQTQVPMQPQLLQMRPHLQANLSAQTPVTVPAHVRVMRQQQAQIIPGQRLPVASSSAAMATMTRSIVTSTAGTSTITGRPVATTLNNSNPTVAQLQSMANAMNGAGGGGQLIMTSSGQLLVIPTPSKQTTQHHRPGQPGQGVIIQQQQPAELHPQPGGGYIVSQPSPVAAASSSSSSSTVILNSGGAKLLHHQIITSQAGQINQATSGGSGNQPQTVLLNTLPNGGYIVQQQPQTQSPQQAEQILAMPQPPPAQTLIISSPDTKRRARKRKSSVCHTPPPSGSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKIISPQISPSIPNQAPALLHQQAAAAAAAAPQFQ---QQFQLSPGIQGIVVNKPNPPQQPQTQQLLLQNGQILQQVNLIGQQLLMPAGLVMGPDATLLQIQNMPATSLMTPQGPVMLRTPSPQNKPSFISPSAGGQQYLVGANGQLSPIGQIYSTPMGLVMPTGQQGGASFVQASPTTTTIQIQQQPAPQPTQISLQPAQATYMTETVMSRQGTAASPPDTTTCSPRSPERPSSHRSSGSDMVQCVSSSEPDAAVSPQSTESRQSPSSTDCERSICKNNVFTQPSGIYKHSEPKIRRIHITSQTSAENGISLMQGQESPTTTQLLSSVPTAQPTVEKTTVRTPTKRSRRPQRGAARAAPSASDKSFPLPPRSFAIGELIWGPARGHPAWPGKIVKMPDGVCTPSQQFDHVWVQWFGGGGRSTSELIPVNSLQSLSEGLEAHHKAQKDTRKSRKLNSQLERAIQEAMTELDNISASSTPAATSSSSATISAVPASAGPAVIGGQQQYQQQQQQQQQQQSPSSTNNKINGLARSKRQANTSGASMVLTTSTAATLSGLFNQQRAKPIRIAPAPPVATTGTGNIGTIAAAGAAAASTGTGTATTSARSEILKLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ... : ::. :::. . : *. :: . .::. :*: . . : :: * . :*: :: : ::. : :: : *:..: * . .:: . *: ::: :: :. .: ::. : .* * : :..: . :.: : .*:. : ..: . .. ***..:* . : * . : . :*..* : :*.. : ** :. . :* .. :.. . . *.: :. . . . :* * ::. . * ::. : * * . ::: . . :.: .:. . . ::.. : : : ..: .** .. .:. :.. ... ::*.: : ::*: :*:*...* * * .: * . . .. *..:: :.: ** :* ::*.... : .. : * ::** * : : :*:.. ...: :: **..:.:: * : .* :*:: .: .. *. :*: .* : :.::... : . . . ::: * *. *:*. : .. :: :.* . :* .:: . ::.* ** :* .:.:.*...*. : . :. .:* .:*.*: :.:: . :* . : ... * * * .. *. * *. :*:*....: :* . : ** .*: :.. :* . : .: * .* *. * .. *. :. ***. . .:: :..*. .: * :* : : : . : :*:.*. *.* : . :* * :: : * . ::: *. * *. : : * .::: .:. : *.:*. ..*. :: *: : *:. .*. * * :* * *.: . : :.. ::: : **.: : *: : *. * * : .. * .*: . : . .* ::*. *: * :. **.: :. . * :: *:::. :.* . :. .:.*. :* : : ..:*: :. .. * ..*... * .: . *.: : . . .:* . * :. :. .*. **. * : * : .* : * : * ::: :.:: *:: * . : *: .. .: :. :. .:. . * :* .:***: .*: . . : .:.: . ** :. :: : . . : * : .: :* * .:.*: . *:.. * * * .: : :::: :.... . : . : .* :: *.* . . . ** :*:: .*: * : :** . . . .... * :* : ", "identical_positions": 183, "similar_positions": 577, "identity": "10.03%" }, { "cls_id": "homologset.agr.MGI:2138935", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPZ9-1", "uniprot_id": "A0ABK0LPZ9_RAT", "id": "A0ABK0LPZ9-1", "name": "", "aln": "----------MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDG----GDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVR------KELKGGKAYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLS------GDPCFKTPPSTAKS---------------------------ISIPGQDSSLQLTCKGGGTSSGGSSSTNSLTGSRPPKAR------------PTILGSG---LAEEPEQSLSSPEEVFHS------------------------------------------------GHSRNSSYASQQSKLSGHS----TEHSRSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTS-----------------SSASGGLSMTVEGPEGSEREHRP---------SEKPPRPPEKPPRPPRP----LHLS--------------------------------------------------------DRSF----RRKKDSVESHP---TWVDDTRIDADDIVEKIMQSQDFTDGSN-TEDSNLRLFVSRDGSTTLSGIQLANRVSSGVYEPVVIESH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T9C2-1", "uniprot_id": "EEIG1_HUMAN", "id": "Q5T9C2-1", "name": "Early estrogen-induced gene 1 protein", "aln": "----------MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDG----GDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCVFRVSVR------KELKGGKAYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLS------GDPCFKTPPSTAKS---------------------------ISIPGQDSSLQLTCKGGGTSSGGSS-TNSLTGSRPPKAR------------PTILSSG---LPEEPDQNLSSPEEVFHS------------------------------------------------GHSRNSSYASQQSKISGYS----TEHSRSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTS-----------------SSASGGLGMTVEGPEGSEREHR----------------PPEKPPRPPRP----LHLS--------------------------------------------------------DRSF----RRKKDSVESHP---TWVDDTRIDADAIVEKIVQSQDFTDGSN-TEDSNLRLFVSRDGSATLSGIQLATRVSSGVYEPVVIESH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q78T81-1", "uniprot_id": "EEIG1_MOUSE", "id": "Q78T81-1", "name": "Early estrogen-induced gene 1 protein", "aln": "----------MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDG----GDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVR------KELKGGKAYSKLGFTDLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLS------GDPCFKTPPSTAKS---------------------------ISIPGQDSSLQLTCKGGGTSSGGSSSTNSLTGSRPPKTR------------PTILGSG---LPEEPDQSLSSPEEVFHS------------------------------------------------GHSRNSSYASQQSKLSGYS----TEHSRSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTS-----------------SSASGGLSMAVEGPEGMEREHRP---------SEKPPRPPEKPPRPPRP----LHLS--------------------------------------------------------DRSF----RRKKDSVESHP---TWVDDTRIDADDIVEKIMQSQDFTDGSN-TEDSNLRLFVSRDGSTTLSGIQLGNRVSSGVYEPVVIESH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RF39-1", "uniprot_id": "A0A8M1RF39_DANRE", "id": "A0A8M1RF39-1", "name": "", "aln": "----------MAFLVKKKKFKFQTHVTLEELTAVPFVNGVLFCKIRLLDG----GDFTASSSREEVHQNCVRWRKRFSFVCKMSANSNTGVLDPCMCRVSVR------KELKGGKAYSKLGFADLNMAEFAGSGWTARCCLLEGYDTKNTRQDNSILKVTIGMTLLS------GDPCFKTPPSTAKC---------------------------ISVAGQDPSLQLDCKGEGT-------AEVLP--RMAKQR------------PSILGSA---LPEEADQSQS-PDESFHT------------------------------------------------GHSRNSSYASQQSKLSGYS----TELSCSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDLTHRR----------------------------------------------------------------------------------------------------------------------------------------------------------NTSTG-----------------SSVS------ADAP--SESDSR-----------------PDRPPRPPRP----ILPS--------------------------------------------------------SRPP----RRKQDSVEDQP---TWVNDTRIDADDIVEKIVQSQNFSDISN-NEDSNLRLFVSRDGTTALSGIQLGNRVSAGVYEPVVIESH---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VID5-1", "uniprot_id": "Q9VID5_DROME", "id": "Q9VID5-1", "name": "C2 NT-type domain-containing protein", "aln": "MTLLGPSAPGMAFMMKKKKYKFNVEVQLQDLVEVALVNEVLFAKIRLLDG----GSFQEYSSREEVRNHRVEWNRSFEFPCKMSANASTGVLDPCHLRISIR------KEMKGGRSYYKLGFIDLNLAEFAGAGLTSRRFLLEGYDSR-HRLDNSMLRVSIKMHMLS------GDILFKAPTPNLKSKQSKPSIDDFSNAATGVGLQIPTATALPSIGGGSGGASVSLGGSGVTLGGIPGNQSLPGTRPVSTTKEEDIDNQALIAAIVTDSG---LSESSESGVTLTTDNLQQHGSVVVANPISPVTQALPQLGIIGSNNYGTTGGAIGFTGAGNATLIEMGHSRNSSNTSQMSKGSGYSSFSHSQHSRQSSEGDSGHASRQNGQKGDEHQQCNSLRVVVAKSHHVHTHLSLSTTVEYASDEQLYQTPNATMTNSQKLAFEDFRTPMAELAAPLFQPMGAGCSGTPSSTYRSAGSPSHNTQYYDSGEASDTDECLNDESGDNDSGLEENFHTPRVAKIKSMENLSILEMEFHKASMELDRNSPRRLKQLAEHAQIPKMKSLNNLCFDHYAEQSVREEFQRMHEQSLEERMRFQQHHQLRKNSNASNGSATKIYVKHLSHQNHYHIKVGNAKFIGQDGNDSPQSMHYPIQKMRSMGTIQDIVSDRIEPDPFLTPTTERKPNFSRLVQSAEKPVLGSSYVNRLLTYDAVDSPSEPFNSSVSFMSRTPFQRAYRRNIQQGSSSTPLATQDFFAVRPHSTNAAYELMRNFSGVPRRLFDGNITTAGQNSNMGAVSTNRQQQPCAPGTNSFIGSNSSPSGTLASIHSSHSASSSNGSNSSSSGAVITFQCTAGSGQDTVDSANHQQQMTVGSPNGHGSNPRLGNVMSGDVISSMAASPTDACSIRSNPSAASLLLSTSAAAAEASALASATTMSVSGATLSPLATTQIIRRPSITMMNPSSGSLVISETGSLDRTKSSGEKRKKGALDDGPRVSDRVEETRVNPDSLIDEILKDTKLDQLEESAETSGLQLYIARDGTASLGGHEVKSSVRAGALKQVVMQDRR--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38177-1", "uniprot_id": "YBI6_YEAST", "id": "P38177-1", "name": "Uncharacterized protein YBL086C", "aln": "--------MPFNHNSKAKRPKFLLDLQIKELVNIPQSSGYCYTKWRLKDGTGTSGHKVALDGEHQTTSTQSRGTTKHVHVQHHRAQWNYSLDKPILVKLHLDKNGRFLKKILVLDVFFEFADANSSLTSSSSPNGKVKKTTYANATALTATGNNSYSQKITGKLLLGTVDIDITEYVKEDETPTTNR-----------------------FLLKHSKVNSIINVSLQLKLVRGSYEDFNISKSFTNGQLANYRPG---------INTILDNTSELSSPTSTTNQMSPKNTFSN------------------------------------------------FNGIGTTVAKPGTNATGNSTSIKSPTSTNHK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSEMTTKPG--------------------------------------------------------------------------------------------------------------------------------------------------------LSTTIS-----------------SSMSPLIESLYQKTFKLPWDPRPGEFTPRECVEDILQGGNGWAKNEKGINLIDLQALRLN----------------------------------------------EMEEEYYNPNYGNNLGNKASSWPPNPSDDGYSTMGKREYLEKKQNWSHMSRAQRAKLRTHNDEDNENTANDKGSDKDNNSVEDNNPTDFLTDRIRENKNWSIITPSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *: ** . :::*. :. . : * ** ** * ....:. . . . . : *: .: .* :: : *:: : ::. : .::. :... . : . : :** : :*. : : ... : * . . .: : :. : . : .. . . . . : : :. .:: :. :: :* * : * . . : * : .:: . .* . . : * : . .* .: * : : :: : . . . . :.* : .. .: :. : :.: ", "identical_positions": 27, "similar_positions": 127, "identity": "2.53%" }, { "cls_id": "homologset.agr.MGI:2138937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMQ2-1", "uniprot_id": "TF3C4_MOUSE", "id": "Q8BMQ2-1", "name": "General transcription factor 3C polypeptide 4", "aln": "MSEADQALVGPKADEPSPPAEEKDEGGG----KEAAADAAPGPSASFRLMVTRREPAVKLQYAVSGLEPLSWSEDHRVSVSTARSVAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKVGSKTEVAECKEKFASSKDPTISQTFMLDRMFNPEGKALPPMRGFKYTSWSPMGCDANGRCLLAALTMDNRLTVQVNLNRLQWVQLVDLTEIYGDRLYETSYRLSKNEAPEGNLGDFAEFQRRHSMQTPVRMEWSSICTTQQVKHNNECRDVSSVLLAVLFENGNIAVWQFQLPFVGKESISSCNTIESGISSPSVLFWWEYEHNNRKMSGLIVGSAFGPVKILPVNLKAVKGYFTLRQPVVLWKEMDKLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTGLHSLPIVSITADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGIAVSPCGAYLAIITTEGMMNGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLIDLVRWKILKDKHIPQFLHEALEKKIESSGVTYFWRFKLFLLRILYQSMQKSPSEALWKPTHEDSKILLVDSPGMGDGEDEQQEEGTS-KQGTKAGLQEKSKEG-DTEETPEDSLTAGGDTGGREPVEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDEDYDDRTAQVLIGHISKKMNKQTFPERCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSCQSLIYRRCLLHDSIARHPVPEDPDWIKRLLQSPCPFCDSPVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AGY8-1", "uniprot_id": "A0A8I6AGY8_RAT", "id": "A0A8I6AGY8-1", "name": "", "aln": "MSEADQARVGPKADEPSSPAEEKDEGGG----KEAAADAAPGPSASFRLMVTRREPAVKLQYAVSGLEPLSWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKVGSKTEVAECKEKFASSKDPTISQTFMLDRMFNPEGKALPPMRGFKYTSWSPMGCDANGRCLLAALTMDNRLTVQVNLNRLQWVQLVDLTEIYGDRLYETSYRLSKNEAPEGNLGDFAEFQRRHSMQTPVRMEWSSICTTQQVKHNNECRDVSSVLLAVLFENGNIAVWQFQLPFVGKESISSCNTIESGISSPSVLFWWEYEHSNRKMSGLIVGSAFGPVKILPVNLKAVKGYFTLRQPVVLWKEMDKLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTGLHSLPIVSITADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGIAVSPCGAYLAIITTEGMVNGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLIDLVRWKILKDKHIPQFLHEALEKKIESSGVTYFWRFKLFLLRILYQSMQKSPSEALWKPTHEDSKILLVDSPGMGDGEDEQQEEGTS-KQGTKAGLQEKSKEGGDTEETPEDSLTAVGDTGGREPIEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDEDYDDRTAQVLIGHISKKMNKQTFPERCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSCQSLIYRRCLLHDSIARHPVPEDPDWIKRLLQSPCPFCDSPVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKN8-1", "uniprot_id": "TF3C4_HUMAN", "id": "Q9UKN8-1", "name": "General transcription factor 3C polypeptide 4", "aln": "MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKLQYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKVGSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRCLLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQRRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESISSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPVILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTGLHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGIAVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLIDLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPTHEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEG-DVEEPTDDSLPTTGDAGGREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDEEYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSCQSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDX7-1", "uniprot_id": "A0A8N7TDX7_DANRE", "id": "A0A8N7TDX7-1", "name": "", "aln": "----MAALCSNSSSEKAGTASEAPSGPE------DDFWAGQGP-------IVLRDPAIKLLSPVSGVEPLSWAEDHRLAACNTNSVSLMELVCDIHSLSQNLVLHRTHIPVPTTTCELKVGSEKDVRAVKESFANSKDPVVSQMIMIDRVINP---QCGPLHGVKYTSWSPLGCDKLGRCLLAFLTLDNRLTIHSSHLQLQWTLLLDLTELYGEMLKTRKYSAQNDGTPPVSFKDFDELQRRFRMQTPVRMEWSSLCSMQQVQSDNAHKDINTVLLAVLMENGDVVVWQFSLPLNGKESVVSCSTIKSGVSSPSALTWWQYEHSGRKMSGLIIGSSVGPVKILPVNIKAVKGYFTLRQPVVLWQESDQIPVHNIKCITLFHPHQKCNCSLVVAARGPYIFWCLLLISKAGLNVHNSHITGLHSTPIISMTACHNNGTVLTCSLDGKVKKLTTVFTDLAVEFKQEEIVLPEGVAGRRIHGISISPNSAYLAVLSNEGMNNGFHPVALNYQVQFITFKTPDEAAAKMLD--AHCLFRNSDLLDLLRWRILKDKSIPSAYENNLEEKLQTSGSTYLWRLKLFFLRTLHKSMQKTPSEALWQPRRRSGQSLVGDGDEGGGGDEDEMMEDRQ------------------------------GDAEIRE-REERMKEIGSRIEAVESHLIRENMKKVLGEVYLHTCVTQNTRVPTKGVCDFLTNDPANEDRAAKVLIGHIMNKMNKQTFPEYCALCKEILPFTDCKRAECKNGHRWLRCALSYQACQGVTYRRCLLQDSIASVAEPEDSDWIKKILQGPCIFCDSPFY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : ...* .* *. ** :. *:**:** .***:***:*:****::...:.*::::**:**:*. .*:**:*** :*.* .:* *****:.:* **.** ****.:** :*:**::** *::*.*******:*** ****** **:*****:: . :***. *:****:**: * .* .:: :* .: ** *:***. **********.:*: ***: :* :*:.:******:***::.****.**: ****: **.**:**::***.* **:***..*******:**:.**:******:*************:**:* *::***.***:.*:**:***.*********.*:******************:***** **:*:** ::**** *** ****::* .:***:*::*::: * *.: ... * ***::** .****:::.*** **:*** ******:*:** :****::*: .: **:: **:**:**:***** **. .: **:*:::** **:**:***:** *::****:******:* :...: *: *. *..:::: *. . **: ** **:: ** .:***** ** **:**:********* :*:** :**:*:*:** .* :**:*:****** :********* *:********** *:* *.*** **** *:**:**.: ******:**** . ***.****::**.** *****.:", "identical_positions": 440, "similar_positions": 213, "identity": "53.46%" }, { "cls_id": "homologset.agr.MGI:2138939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V752-1", "uniprot_id": "G3V752_RAT", "id": "G3V752-1", "name": "RNA cytidine acetyltransferase", "aln": "MHRKKVDNRIRILIENGVSERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYKKELG-FSSHRKKRMRQLQKKIKSGTLNIKQDDPFELFVAATNIRYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTMTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLNILPISSHVASIEALPPQAPDENLSPAALELQELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIVQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRQQSAQS------QVSTTAENKTTTTARLASARTLHEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITR---IVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPTQN-ALPEVLAVVQVCLEGELSRQSILNSLSRGKKASGDLLPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGRFPCLEEK---VLETPQEIHTVSSEAVS---LLEEVITPR--KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLADEDEAERGAWLAAFWTDFRRRFLALLSYQFSTFSPALSLNIIQNRNIAKSAPP-------VLGREHLEALFLPYDLKRLEMYSRNMVDYHLIMDLIPAISRLYFLNQLGD-LALSAAQSALLLGMGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNDVQEKAIEEQMVAVKDVVMEPT-------------IKTLSDDLDEA-AKEFQEKHKKDVGKLKDMDLSQYIIRGDDEEWN---EVLSKAGQN--ASIVSLKSDKKRK---LETKQEP-KQSKKLKKSGN-NRKDTKLKRKK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K224-1", "uniprot_id": "NAT10_MOUSE", "id": "Q8K224-1", "name": "RNA cytidine acetyltransferase", "aln": "MNRKKVDNRIRILIENGVAERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYKKELG-FSSHRKKRMRQLQKKIKSGTLNLKQDDPFELFVAATNIRYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTMTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLDILPISSHVASIEALPPQAPDENLSPAALELLELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIVQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRQQSAQS------QVSTTAENKTTTTARLASARTLHEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITR---IVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPTQN-ALPEVLAVVQVCLEGEISRQSILNSLSRGKKASGDLIPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGKFPCLEEK---VLETPQEIRTVSSEAVS---LLEEVITPR--KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLADEDEAEQGAWLAAFWKDFRRRFLALLSYQFSTFSPALSLNIIQNRNVAKSALP-------ALGREHLEALFLPYDLKRLEMYSRNMVDYHLIMDLIPAISRLYFLNQLGD-LSLSAAQSALLLGIGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNDVQEKAIEEQMVAVKDVVMEPT-------------MKTLSDDLDEA-AKEFQEKHKKEVGKLKDMDLSQYVIRGDDEEWN---EVLSKAGQN--ASIVSLKSDKKRK---LETKQEP-KQSKKLKKRDN-NRKDMKLKRKK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0A0-1", "uniprot_id": "NAT10_HUMAN", "id": "Q9H0A0-1", "name": "RNA cytidine acetyltransferase", "aln": "MHRKKVDNRIRILIENGVAERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYKKELG-FSSHRKKRMRQLQKKIKNGTLNIKQDDPFELFIAATNIRYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTVTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLNILPISSHVATMEALPPQTPDESLGPSDLELRELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIIQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRQQSAQS------QVSTTAENKTTTTARLASARTLYEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITR---IVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPTQN-ALPEVLAVIQVCLEGEISRQSILNSLSRGKKASGDLIPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGRFPCLEEK---VLETPQEIHTVSSEAVS---LLEEVITPR--KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLTDEDEADQGGWLAAFWKDFRRRFLALLSYQFSTFSPSLALNIIQNRNMGKPAQP-------ALSREELEALFLPYDLKRLEMYSRNMVDYHLIMDMIPAISRIYFLNQLGD-LALSAAQSALLLGIGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNEVQEKAIEEQMVAAKDVVMEPT-------------MKTLSDDLDEA-AKEFQEKHKKEVGKLKSMDLSEYIIRGDDEEWN---EVLNKAGPN--ASIISLKSDKKRK---LEAKQEP-KQSKKLKNRETKNKKDMKLKRKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53914-1", "uniprot_id": "NAT10_YEAST", "id": "P53914-1", "name": "RNA cytidine acetyltransferase", "aln": "MAKKAIDSRIPSLIRNGVQTKQRSIFVIVGDRARNQLPNLHYLMMSADLKMNKSVLWAYKKKLLGFTSHRKKRENKIKKEIKRGTREVNEMDPFESFISNQNIRYVYYKESEKILGNTYGMCILQDFEALTPNLLARTIETVEGGGIVVILLKSMSSLKQLYTMTMDVHARYRTEAHGDVVARFNERFILSLGSNPNCLVVDDELNVLPLSG-AKNVKPLPPKEDDE-LPPKQLELQELKESLEDVQPAGSLVSLSKTVNQAHAILSFIDAISEKTLNFTVALTAGRGRGKSAALGISIAAAVSHGYSNIFVTSPSPENLKTLFEFIFKGFDALGYQEHIDYDIIQSTNPDFNKAIVRVDIKRDHRQTIQYIVPQDHQVLGQAELVVIDEAAAIPLPIVKNLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRNQNNTSGRESTQTAVVSRDNKEKDSHLHSQSRQLREISLDEPIRYAPGDPIEKWLNKLLCLDVTLIKNPRFATRGTPHPSQCNLFVVNRDTLFSYHPVSENFLEKMMALYVSSHYKNSPNDLQLMSDAPAHKLFVLLPPIDPKDGGRIPDPLCVIQIALEGEISKESVRNSLSRGQRAGGDLIPWLISQQFQDEEFASLSGARIVRIATNPEYASMGYGSRAIELLRDYFEGKFTDMSED---VRPKDYSIKRVSDKELAKTNLLKDDVKLRDAKTLPPLLLKLSEQPPHYLHYLGVSYGLTQSLHKFWKNNSFVPVYLRQTANDLTGEHTCVMLNVLEGRE----SNWLVEFAKDFRKRFLSLLSYDFHKFTAVQALSVIESSKKAQDLSDDEKHDNKELTRTHLDDIFSPFDLKRLDSYSNNLLDYHVIGDMIPMLALLYFGDKMGDSVKLSSVQSAILLAIGLQRKNIDTIAKELNLPSNQTIAMFAKIMRKMSQYFRQLLSQSIEETLPNIKDDAIAEMDGEEIKNYNAAEALDQMEEDLEEAGSEAVQAMREKQKELINSLNLDKYAINDNSEEWAESQKSLEIAAKA--KGVVSLKTGKKRT---TEKAEDIYRQEMKAMKKPRKSKKAAN-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3C1-1", "uniprot_id": "NAT10_DROME", "id": "Q9W3C1-1", "name": "RNA cytidine acetyltransferase", "aln": "MVKKKIDNRIRVMIENGVKLGHRTMFIVIGDKARDQVPILYDILTKSTVKARPTVLWCYKNKDEAISNHGKKR----AKKIAVGKVDVNEADLFDSFRVATTIHGRYYSETHAVLGRTYGVCVLQDFEALTPNLLARTVETVEGGGLIILLLKTLQSLKQLYTMSMDVHKRFRTEAHQTVTCRFNERLILSLADCKRCLVVNDDLTVLPLSSKTINVEPVNPAGAGR--SPNEASLKELKESLLTVQPAGALVNLCKTYDQANAVAQFIEALVDKQLKPPMSLTAARGRGKSAALGLSIAAAVAFGYVNIYVTSPHPENLITLFEFVLKGFDALEYQEHADYTIIRSTNADYKKAIIRINITRSSRQTIQYIAPSDTHLLNAADLLLIDEAAAIPLPLVKKMIGPYLVFMASTINGYEGTGRSLSLKLISQLQKDNNAR----------------------------PPLKLEESIRYQENDDIEKWLINLLCLDASTVPS---ISSGCPTPDACELYYVDRDALFSYHKAAEAFLHRLVSIYVSSHYKNTPNDLQMMSDAPAHHLFCLLGPVQRMDA--LPEILVVIQVALEGQISAQSISDSLGRGKKAAGDLIPWNVAEQYGDRDFPKLCGVRIVRVATHPNYQRMGYGKRAIQLLKDYYARKHTNLEDGPVASKDAGKGIEEVEEEELS---LLKEQIRPR--SRIPTLLQRLHERVPEHVDYIGTSYGLTTELLKFWKNAGFVPVYLSQKSNELTAEHSCIMLHTPNATP------WLGLYYQDFRRRVLKLMGKTFREFETKLCLALLKNKSVDTEGSALK-----VLDKPMLDVYFLPHDLQRLESYARQQSEFRLIIDLLTDIAQLYFQGRIDG-LQLDLVQQGILLALGVQGKTVDALGLELNMPGNQLLAKFFDAMKRCNQCFRSVLEEHIEGGMLREADLSKGEE---------LQPLTLSLDKELDQT-AQKLSKQQRKELKRLKAEQLDEFQIKGTEEDWS---KALETNGTGGGSGLLSVKSGVKRLDGPIETREDGDLAAPLSKKKKKNNPKQRRSQGKSLI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* :*.** :*.*** :*::*:::**:.::*: *: :: .: :* . :***.**:: ::.* *** *:* *. :::: * *: * .*: **.*:. :**.*:*:*:***************:*******::::**:::.*******::**** *:***** *. *****:****.. .***::*:* :**:*. . .::.: * .. * .* ****** .**.* **. .** :**:*: .**:.: :* *. .::***.**********::**.**:.** **:**** *:** *****::****** **** ** *::* *.:::**::*::: *. ******* * * *. *:*::**********:**.::**************************.**:::. :.*:*.*** .* :**** .***** : * * *. *:*: *:**:**.** .:* **.:::::**:*****:*****::******:** ** *: : :*: * *:*:.***::* :*: :**.**::*.***:** :::*: * :* *.* *:**:*.:*:* ****.**::**: *: :.. :.: *. *..: :: **:: : * . :*.** :* *: .. :.*:*.***** * ****. .****** *..*:**.**:*:**:. ** : ***:*.* *:. * * . .* :::. . * : *: * *.**:**: *:.: ::::* *::. :: :** .::.. : *. .*..:**.:*:* *.:* : *:::*..* :. * ::: : *..: .: ** : * :..:*::: :: .. :.*: :: :*.:: *.. .*:* : *. . .::*:*:. ** * :: : . * . ", "identical_positions": 408, "similar_positions": 328, "identity": "37.88%" }, { "cls_id": "homologset.agr.MGI:2138953", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADA1-1", "uniprot_id": "D4ADA1_RAT", "id": "D4ADA1-1", "name": "", "aln": "MVHERWKTVGGASQLEDRPRDKPQRAGCSYILCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAP-PPIVSTGAAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRTLSEHQAQPRLDG--APELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGPHASYAD--GVEWSSWTGWQYSLKFSEMKIRPLREDR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AV25-1", "uniprot_id": "FBCD1_MOUSE", "id": "A2AV25-1", "name": "Fibrinogen C domain-containing protein 1", "aln": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAP-PPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDG--APELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYAD--GVEWSSWTGWQYSLKFSEMKIRPVREDR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N539-1", "uniprot_id": "FBCD1_HUMAN", "id": "Q8N539-1", "name": "Fibrinogen C domain-containing protein 1", "aln": "MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAP-PPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYAD--GVEWSSWTGWQYSLKFSEMKIRPVREDR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMA3-1", "uniprot_id": "A5PMA3_DANRE", "id": "A5PMA3-1", "name": "", "aln": "MLNDRWGIMNSSPELEDGQRGKNQRMSCSYLLCTILLFVAVLLAVTVTGTILLMNHYQAPPMSDGPPHISTNQDEAN-ALVTVERGDGSRINIFIDPNCPDYNSNFLRLEGVQTSLLHSLTDHDTDLKSVKGQDRALLVNLAEEVAKLSAHAGQLKMDYESLRRGQSNLGQDLNTLQTEQSRLIQLLSESQINMVKVVNSVSDALNAMQKETGGLKARVKADLQRAPVRGVRLKGCANGSRPRDCSDIYASGQREDGIYSVFPTHYPAGFQVYCDMSTDGGGWT---RREDGSVNFFREWDSYREGFGKITGEYWLGLKQIHALSIQGNYELRIDLEDFENSTAFAQYGVFGVGLFSVDPEDDGYPLT-IADYTGTAGDSLLKHNGMKFTTKDRDNDHSENNCASFYHGAWWYRNCHTSNLNGQYLRGQHTSYAD--GIEWSSWTGWQYSLKFTEMKIRPTRDERETK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VME7-1", "uniprot_id": "Q9VME7_DROME", "id": "Q9VME7-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "-------------------------------------MRSVWIYVAFLG------------------------------------------------------LSFYSTEAMDSESFQNDTAIRNKP-----------------------------------------------ELKSLYKLVLALLEENQSNASTEN-----------------IQKSSSDLNTTGLSGRYPSQCPTYPPAHGIYTVQVLGLKP--------------FQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHY-----DEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRPKCHCSG--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : *:. * .* *. ::. :: : . *:: :: **.*.* : : .:**: : * *.. . .:. : * : *** ** * *** ** ...:**** * *::***:: *:.::**.::**:: . :** :.****:. * :*:* . : ::.*:. *.:* :.:::* ****:::: . .*:* ***.* .:*** * ****: ** *** * *::* . .* : *: * ** .** *. :* :** . ", "identical_positions": 90, "similar_positions": 94, "identity": "19.23%" }, { "cls_id": "homologset.agr.MGI:2138968", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL4-1", "uniprot_id": "CLP1_RAT", "id": "Q5PQL4-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MSEESNDD------------KKPTTKFELERETELRFEVEAS-QSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSG---RTEVAYVSKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGR-RPTYVELDVGQGSVSIPGTMGALYIERPADVEEG------------FSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGYG-YQALVHAASAFEVDVVVVLDQER--LYNELKRDLPHFVR---TVLLPKSGGVVERSKDFRRECRDERIREYFYGFRG-CFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRD-MVHHLLSVSTAEGTEEN-----LSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIM-DIRFMDLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LI9-1", "uniprot_id": "CLP1_MOUSE", "id": "Q99LI9-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MSEESNDD------------KKPTTKFELERETELRFEVEAS-QSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSG---RTEVAYVSKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGR-RPTYVELDVGQGSVSIPGTMGALYIERPADVEEG------------FSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGYG-YQALVHAASAFEVDVVVVLDQER--LYNELKRDLPHFVR---TVLLPKSGGVVERSKDFRRECRDERIREYFYGFRG-CFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRD-MVHHLLSVSTAEGTEEN-----LSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIM-DIRFMDLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92989-1", "uniprot_id": "CLP1_HUMAN", "id": "Q92989-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MGEEANDD------------KKPTTKFELERETELRFEVEAS-QSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSG---RTEVAYVSKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGR-RPTYVELDVGQGSVSIPGTMGALYIERPADVEEG------------FSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGSG-YQALVHAASAFEVDVVVVLDQER--LYNELKRDLPHFVR---TVLLPKSGGVVERSKDFRRECRDERIREYFYGFRG-CFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRD-MVHHLLSVSTAEGTEEN-----LSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIM-DIRFMDLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3I6-1", "uniprot_id": "CLP1_DANRE", "id": "E7F3I6-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MTAEAAEKSVEEGLSSSGSAGSSGTRFDLDKETELRFEVEAG-ERVQLELLSGLAEIFGSELNRNKKYTFGPGSKIAVFTWQGCGVALSG---KTEVAYVSKDTPMLLYLNTHAALEQMRRQAEKDNERGPRVMVVGPTDVGKSTVCRMLLNYAVRLGR-RPTLVELDVGQSSVSVPGTMSALCIERPADVEEG------------FSVQAPLVFHFGSTTPGTNIKLYNKLTSSLADAFSQRCEVNRRASVGGCIINTCGWVKGSG-YQALVHCASAFQVDVVLVLDQER--LYNELKRDLPHFVR---VVLLPKSGGVVERSKDCRRETRDEKIREYFYGFRGTSFYPHAFDVRFSDVRIYKIGAPSIPDSCLPLGMSQDDTQLKLVPVSPGRD-LTHHVLSVSSVDDEAEVGQSRGILESPACGFIVVTAVDTQAQVMTVLSPAPRPLPRHTLLIM-DIRFIDLK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K284-1", "uniprot_id": "CLP1_DROME", "id": "Q7K284-1", "name": "Protein CLP1 homolog", "aln": "------MSEDQGKD------------------YTLESDSELRFEIEQKDAKVLVSLVSGFAELFGTELVKKKQYEFGVGAKVAIFTYQGCVLHVSG---KMDVCYISKETPMVQYVNCHAALEQFRMEAEEKDRYGPVAMVVGPMDVGKSTLCRILLNYAVRVGR-RPLYADLDVGQGSIAISGSVATILIERPANVEEG------------FAKTAPLVYHFGHKSPSGNSVLYNAVVSKMAEVTLQSLNSNKRTKSSGIIINTCGWVKGSG-YAHLLHAAKAYGACAIFVLDQER--LYNELLRDVPKGVH---VVLLPKSGGVVERSKELRHEARDQRIKEYFYGNTRAPFYPFSFEVKFQDLRLYKIGAPPLPDSCMPIGMKAEDNKTKVVAVTPTPA-LIHHVLALSFAESVEDD-----VIGTNVAGFCCVTEVDMERQAVMLLSPQPRPLPPNALLLWSELQFMDNHT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08685-1", "uniprot_id": "CLP1_YEAST", "id": "Q08685-1", "name": "mRNA cleavage and polyadenylation factor CLP1", "aln": "MASLPGIDEHTTSEELITG-------DNEWHKLVIPKGSDWQIDLKAE-GKLIVKVNSGIVEIFGTELAVDDEYTFQN-WKFPIYAVEETELLWKCPDLTTNTITVKPNHTMKYIYNLHFMLEKIRMSNFE----GPRVVIVGGSQTGKTSLSRTLCSYALKFNAYQPLYINLDPQQPIFTVPGCISATPISDILDAQLPTWGQSLTSGATLLHNKQPMVKNFGLERINENKDLYLECISQLGQVVGQRLHLDPQVRRSGCIVDTPSISQLDENLAELHHIIEKLNVNIMLVLCSETDPLWEKVKKTFGPELGNNNIFFIPKLDGVSAVDDVYKRSLQRTSIREYFYGSLDTALSPYAIGVDYEDLTIWKPSN----------VFDNEVGRVELFPVTITPSNLQHAIIAITFAERRADQAT---VIKSPILGFALITEVNEKRRKLRVLLPVPGRLPSKAMILT-SYRYLE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : :: ::::: : :.: :*:.*:**:** ..:: * *..::: . : . :. :. : .* * * **::* . : ** .::** :.**:::.* * .**::.. :* :** * .::.* :.: *. :.: : *:* :** . * ** * :.:. * . : :. .* :::* . : * * . . :.** .* *:::: : . : .::** .** .. ::. : *:***** : *.:: * :.*: ::* . :. : : ::..*: : * ::::: .: : : : ** :* *: : : . :* * * ** : ::: . :::: ", "identical_positions": 72, "similar_positions": 156, "identity": "15.16%" }, { "cls_id": "homologset.agr.MGI:2138982", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMA9-1", "uniprot_id": "F1LMA9_RAT", "id": "F1LMA9-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "MEDRR--PHLEATPRNPPTNHRGPIDG----EVPPRARNQANNPAA-----------------------TNHAGRHPRASNHAAPFRQREERFRAMGRNPHQGR-----------------RNHEGHTSDEARDQRQSQ-NDTRR--------------------------------------RNDDQEGRNHRPPWSSDSFQQWHTPLQ-----------------KPAEQPQHTKRLGYKFLESLLQKEPSEVAITLATSLGLKELLSHSYMKPSFLQLICQVLRKACSSRIDRQSILHVLGILNNSKFLRVCLPAYVVGMITEPVPDIRNQYPEHISNIISLLQDLVSVFPASSVQETSMLISLLPTSLNALRASGVDIEEETEKNLEKVQAIIKHLQEKRREGTLRVDTYTLVQAEVEG--EVESYRAMPIYPTYNEVHLDERPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILKLLQSFEDQC-----LRKRKFDDIRIYFDARIITPMCSASGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSK-DNFETFLFATVSNREHEDLCQGIVQLCFNEQSQQLLADVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECDSYVREPRYLLMGGK-YDFTPLIENPSAIRKSLRGAEVLRRSKINVLDFSQWPVKEALNLDDSQMKALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNKSVWQISAQKFPILVVCYTNHALDQFLEGIYGCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRTLPMHLRRAYMNIVTEMKESEQKLQVGAQTLECTMHGVLREQHLEKYIAPQHWESLMNGPVQDADWLCVQPSKHSMIVEWLGLGVGSFTQSASPAGPENTAQAEGEEEEEGEEEGSLIEIEEEADLIQADRVIEEEEVVRP-RRRKKEENGADQELAKMLLAMRLDQDVPG------TTAGPEQAAE-EWETQRSQKKKMKRRVKVELRKLNTITEAEASAIQDVWQLDLSSRWQLYRLWLQMYQSDTRRKILSYERQYRTWAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQQVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNVPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCQYLLCQ-EYLPSQITILTTYTGQLFCLRKLMPVKTFAGIKVHVVDKYQGEENDVILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCIGNMQMLAKVP--LWSRIIHTLRENHQIGPSLRLCCQNHPETHTLVSKASDFQKVPEGGCSLPCEFRLACGHVCTRACHPYDSSHKEFQCMKPCQKVICQDGHRCPNVCFQECQPCQVKVPKIILKCGHKQMVPCSVSESDFCCQEPCSKVLRCGHRCSHLCGENCVRLCPEKVTVKLNCGHSQLVKCGQVEDLKYG-LPVKCTTKCDTTLDCGHACPGSCHSCFEGRFHERCQQACKRLLVCSHKCQEPCMGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCTWRCQHYQCTKLCSEPCNRPPCYVPCTKLLACGHPCIGLCGEPCPRKCRVCHLDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRYMNEQKD-----DEVAIKLKVCPICQVPIRKNLRYGTSIKQRLEEIETVKEKIQGSAGEIAASQERLKALLKSKTLFHQLRPEEFLILQEKLTQKNLSVKDLCLVENSISFYDHLANLEGSLEKVHQLERQKVR------TRLEQVHEWLARRRLGFSSQELSDLQSEIQRLTYLVNLLMRCKITE---VKGSIAEEVSSIRNILEKTCKFTQEDEQLVQKKMDALKTTLPCSGLGISEEERVQIVTALGVPRGHWFKCPNGHIYVITECGGAMQRSTCPECQEVIGGENHTLERSNHLAPEMDGAQHPAWSDTANNLMNF-EIHRMM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R151-1", "uniprot_id": "ZNFX1_MOUSE", "id": "Q8R151-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "MEDRR--PHLEARPRNPPANHRGPMDG----ELPPRARNQTNNPAA-----------------------TNHAGRHLRASNHPAPFRQREERFRAMGRNPHQGR-----------------RNQEGHTSDEARDQRQSQ-NDTRR--------------------------------------RNDDQEGRSHRPPWSSDTFQQWHTPPQ-----------------KPGEQPQQTKRLGYKFLESLLQKEPSEVAITLATSLGLKELLSHSSMKPSFLQLICQVLRKACSSRIDRQSILHVLGILNNSKFLRVCLPAYVVGMITEPSPDIRNQYPEHISNIISLLQDLVSVFPASSMQETSMLISLLPTSLNALRASGVDIEEETEKNLEKVQAIIKYLQEKRRQGSLRVDTYTLVQAEAEG--EVESYRAMPIYPTYNEVHLDEKPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILKLLQSFEDQC-----LRKRKFDDIRIYFDARIITPMCSASGIVYKVQFDTKPLKLVRWQNSKRLLYGSLVCMSK-DNFETFLFATVSNREHEDLCQGIVQLCFNEQSQQLLADVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVQCDSYVRNPRYLLMGGR-YDFTPLMENPSAMRKSLRGAEALRHPRINVFDFGQWPSKEALKLDDSQMEALQFALTKELAIIQGPPGTGKTYVGLKIVQALLTNKSVWQINTQTFPILVVCYTNHALDQFLEGIYGCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRTLPMHLRRAYMSIVTEMKESEQKLQEGAQTLECTMHGVLREQHLEKYISAQHWESLMSGPVQDADWVCVQPSKHSMILEWLGLGVGSFTQSASPAGPENTAQAEGEEEEEGEEEGSLIEIAEEADLIQADRVIEEEEVVRP-RRRKKEENGTDQELAKMLLAMRLDQEVPG------TTAGPEQATE-EWETQRGQKKKMKRRVKVELRKLNTMTKAEANGIQDVWQLDLSSRWQLYRLWLQMYQADTRRRILSYERQYRTWAERMAELRLQEDLHILKDAEVVGMTTTGAAKYRQILQQVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCQYLLCQ-EYLPSQITILTTYTGQLFCLRKLMPVKTFAGIKVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCIGNMQMLAKVP--LWSRIIHTLRENNQIGPSLRLCCQNHPETHTLVSKASDFQKVPEGGCSRPCEFRLACGHVCTRACHPYDSSHKEFQCMKPCQKVLCQDGHRCPNVCFQECQPCQVKVPKIILKCGHKQMVPCSMSESEFCCQEPCSKILRCGHRCSHLCGEDCVRLCSERVTVELKCGHSQLVKCGNVEDIKYG-LPVKCTTKCDTTLDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCTGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCVWRCQHYQCTKLCSEPCNRPPCYVPCTKLLACGHPCIGLCGEPCPKKCRVCQPDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRFMNEQKD-----DEVAIKLKVCPICQVPIRKNLRYGTSIKQRLEEIEIVKEKIQGSAGEISTSQEQLKALLKSKTLFHQLRPEEFLILQEKLAQKNLSVKDLGLVENSIRFYDHLANLEGSLEKVHCGEQQSVR------TRLEQVHEWLAKKRLSFSSQELSDLQSEIQRLTYLVNLLMRCKMAEK--VKGSIAEEVSSIRNILEKTSKFTQEDEQLVQKKMDALKTTLPCSGLGISDEERVQIVTAMGVPRGHWFKCPNGHIYVITECGGAMQRSTCPECQEVIGGENHTLERSNHLASEMDGAQHPAWSNTANNFMNFEEIHRMM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2E3-1", "uniprot_id": "ZNFX1_HUMAN", "id": "Q9P2E3-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "MEERR--PHLDARPRNSHTNHRGPVDG----ELPPRARNQANNPPANALRGG-----------------ASHPGRHPRANNHPAAYWQREERFRAMGRNPHQGR-----------------RNQEGHASDEARDQRHDQENDTRW--------------------------------------RNGNQDCRNRRPPWSNDNFQQWRTPHQ-----------------KPTEQPQQAKKLGYKFLESLLQKDPSEVVITLATSLGLKELLSHSSMKSNFLELICQVLRKACSSKMDRQSVLHVLGILKNSKFLKVCLPAYVVGMITEPIPDIRNQYPEHISNIISLLQDLVSVFPASSVQETSMLVSLLPTSLNALRASGVDIEEETEKNLEKVQTIIEHLQEKRREGTLRVDTYTLVQPEAED--HVESYRTMPIYPTYNEVHLDERPFLRPNIISGKYDSTAIYLDTHFRLLREDFVRPLREGILELLQSFEDQG-----LRKRKFDDIRIYFDTRIITPMCSSSGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSK-DNFETFLFATVSNREQEDLCRGIVQLCFNEQSQQLLAEVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECNSHVKEPRYLLMGGR-YDFTPLIENPSATGEFLRNVEGLRHPRINVLDPGQWPSKEALKLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNESVWQISLQKFPILVVCYTNHALDQFLEGIYNCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRNLPMHLRRAYMSIMTQMKESEQELHEGAKTLECTMRGVLREQYLQKYISPQHWESLMNGPVQDSEWICFQHWKHSMMLEWLGLGVGSFTQSVSPAGPENTAQAEGDEEEEGEEESSLIEIAEEADLIQADRVIEEEEVVRP-QRRKKEESGADQELAKMLLAMRLDHCGTG------TAAGQEQATG-EWQTQRNQKKKMKKRVKDELRKLNTMTAAEANEIEDVWQLDLSSRWQLYRLWLQLYQADTRRKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCKYFLCQ-EYLPSQITILTTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVP--LWSKIIHTLRENNQIGPMLRLCCQNHPETHTLVSKASDFQKVPEGGCSLPCEFRLGCGHVCTRACHPYDSSHKEFQCMKPCQKVICQEGHRCPLVCFQECQPCQVKVPKTIPRCGHEQMVPCSVPESDFCCQEPCSKSLRCGHRCSHPCGEDCVQLCSEMVTIKLKCGHSQPVKCGHVEGLLYGGLLVKCTTKCGTILDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCIGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCVWRCQHYQCTKLCSEPCNRPPCYVPCTKLLVCGHPCIGLCGEPCPKKCRICHMDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRYMNEQKD-----DEVAIRLKVCPICQVPIRKNLRYGTSIKQRLEEIEIIKEKIQGSAGEIATSQERLKALLERKSLLHQLLPEDFLMLKEKLAQKNLSVKDLGLVENYISFYDHLASLWDSLKKMHVLEEKRVR------TRLEQVHEWLAKKRLSFTSQELSDLRSEIQRLTYLVNLLTRYKIAEKK-VKDSIAVEVYSVQNILEKTCKFTQEDEQLVQEKMEALKATLPCSGLGISEEERVQIVSAIGYPRGHWFKCRNGHIYVIGDCGGAMERGTCPDCKEVIGGTNHTLERSNQLASEMDGAQHAAWSDTANNLMNFEEIQGMM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PND3-1", "uniprot_id": "A0A8M9PND3_DANRE", "id": "A0A8M9PND3-1", "name": "", "aln": "MANPRGGPQRGRGGFSVPPRRDGSVPGHRQASVSPNRRRGSGGRGEGGGGRGGGGGGGRGGGIGGGGRGSGQGGRGRGGGRGRGSGGERDGRGRGDRSHQHTGESTNSLWERWTDGITQSARGRDGRGQRKGENKQHHQGNAVHRPIIMGGATHLPSPYQGKFGRSLPGLMQLNLTPSSMQQPMNSRHDLEGMSLQRTSGGMSDLRASPQGEARTESQRGRGGHWRGRGRDGPPEVRTLGYKTLEGLLEKEASEVAITLSSSTGLRNLLEEKVMRNDLVQLVCQVLCKAFQSRIDRNTVMHLARVVKDSQFFLSILPHHVTGMMSDYMPARRDQYPQHLSNIISLVSDVLNMFPQSSVHSVSMLVTLLKPTINQLRASGVDVLANTDQDLERVQGLVNHLQEKSREGTLRSDKYSFLTADEDAPPGEEDFRMMSIYPSFEEFHLDQKPFLRPNIISQSFPNARIYLDTHFRLLREDFVRPLREGVKELLRIHHTEKTNGIPMKNRQFDDIRVYFDTRVILPLCTSMGIAYKVKFDTRRLQFVRWENSKRLLYGSLVCLSM-DNFETFLFATVTDRDPKLLRQGEVNLCFSPDSRAALARVQPSDSFLMVETTAYFEAYRYVLEGLQEQDENDVPFQRYIVECKTDVDPPAYLLVEGRSYDLSCIAAEGQGK-----------IPPFNPLTQNAWPDEEKMGLDESQLQALKLALTKELAIIQGPPGTGKTHVGLKIAQALLKNHEAWSN---GCPMLVVCYTNHALDQFLEGIHGFLKDGIVRVGGRSNSETLKRFGLRELTRFKDFRKNLPQHLRRAHHEISNNMQEAETLLKAQSAQLECSLRGVLKEDFLEKYISEQHWHSLCLQPLSDG-FETVGKKKPSMMAEWLGIGFSLFFQGPQQTDGEVAEDEDGAQLEEEE----LIDIDEEADLIQAERIVVDAEHGDKDKYKLKVEEKNIAAMAELMLALNLNDAEAQPGQNQTQTHGHAQADEQEWQMQGHQKKKLRQMARKELKKTSAMSEKEERRIRDVWSLSLKDRWKLYRLWVLRYRSDLRTKALASEQVYQEAAERLNEIRRHEDLSVLRQARVVGMTTTGAAKYRQALQQLQPRLVIVEEAAEVLEAHTITTLSKACQHLILIGDHQQLRPSATVYELAKNFSLEVSMFERLVRVNFPFVRLNYQHRMRPSIARLLTPHIYSSLENHPSVLKYDNVKGVLTNLFFVDHIQPEEEIKDGRSHQNPHEARFVVELCQYLLFQ-DYKPSQITILTTYTGQLHCLRKLMPSPKFSGVKVHVVDKYQGEENDIIILSLVRSNPQRRVGFLNIPNRVCVALSRAKMGLYCIGNMDMLSSVT--LWSNIIHTLREHDQVGPALTLSCQNHPDKQIHASCGNDFKGAPEGGCDQPCQYRLDCGHVCTRMCHPYDAEHKEYKCMKDCSKVLCELGHKCTRRCHQECGKCMVSVDKIIPSCQHNQKVPCHKDPAEFVCQVRCEKTLPCGHPCKATCGESCTSQCMVRVPIELKCGHMQEEPCFVSRDHKNE---PRCNTKCGTVLKCGHSCPGTCNGCHQGRLHKACTHKCQQILVCSHECREPCVRDCPPCSSRCQNRCVHSECKKTCGQSCAPCREPCAWQCPHHSCTKLCHEPCDRPPCSVPCNKTLTCGHRCIGLCGEPCPNKCRVCHKEEVTEIFFGSEDEPDACFIQLEDCKHLFEVTGMDQYMNLDEDQGAELDQRAIRLKDCPRCRTPIRRNLRYGTHINRSLAAIEMVKEKINGVPDIIKQQQDVLSLVLNDKTNLKKYLPDKFVSLQEKLDTNVLSIQQLWHLENLMNFLESVGKLKATQVKHESTILERLQKNQPFFRKTEEVLRFLLDPAQRFSEQQVADLGRELKRLSYLAELNERCRMSRFKSPEVVLGTEVQHLRGILEDTLPFSEGLERTVQQMFTKLDVILPRSGLGITEEERVMIVQAVGLNKGHWYKCPNGHVYAIGECGGAMEKTKCPECHAEIGGSNHALTQGNAVASEMDGAQHPAWSDAAN--MANFDLDNFED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCB7-1", "uniprot_id": "Q9VCB7_DROME", "id": "Q9VCB7-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "------------------------------------------------------------------------------MSSSDDDWFDQDENKLLQG------------------------LEKSLKSLELQKNEEYIECPPSER-----------------------------------------------KCPPS------------------------------EVGEYVMQHTRFSLTELTNALKMPAIDMFLYFLSDK--RDLFENQVLATDNVKRVGLFVDVLWS-----------LCELELGGFDEVFLSAFSR----------QTALLDKIKNLLQAKAAVAKCDAESALILSHSKWMLLRAHKHGLLSHQGYELVELYKKLAPSFKSDMIDGLEAFTGNFSHNVKGLIYPTLET--------LLGKDATKAPNEEEDEGLVSDKVVK--------YVNALRNLLREDFLAPLVEFVQQLRSGTDVDELK---QQGLLWSDVHLTLNPQFANAQRHSLVFLKVQFTKESKNAYKTWLNS--IKSGTLLCLTTSLAFDDLILASVGYTEPEKLKEDCLSVQIVKQYNIGNAYNRP---LIMFQAPVFFEPYLRVHNYLSTCSTEKFPMGRYIVDGQMEIPPPAYMKPGVK--------------------------LSFNMKPFTLDKLPEDLHLNESQKTAFKEALCREFSIIQGPPGTGKTHLSVQLVNSLIQNAKALGTG----PIIVLTYTNNSLDKFLVKIS-RYTQEILRFGNQSRDPQISKFNLSTTIKP----ELVPPRLKRIWWLVNCEYKEKFRNLQGLYANFDGSEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SYQDTLAAQEKLNQVAERIETLRMVFQFFLAREKDLLAMTTTCAARHNFLFRLLQSKCVLFEEAAEIQEAHIVACLTPHTEHVILVGDHKQLQPFSGSRKVP-----QISLFERLIVAGLPFSRLNLQYRMRSCISELLVPSIYDELLCSESVKEYEDIRLMSKNLYFVQHNQPEHCMSD-MSIGNLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQNYRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYIVGNVTILKDTFPKIWNPIVKRLKENNAIGEAFPTITST-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: . :. : .::. : . . : . :. . * . *: . :: : : :. ::*:... : . :: : .: . :: . * *. . : :::.*::. : . . *:: ** . : * : : :.* : *.: : :: . : : .: . ::. :: :::. *::: .******: ** * : :* . : : :.*::: ::.:. . : : . * ** : *:*:*:: *: :::*:* : : * .. :.: : : . * :* ::*.::..:**.* * : *. . :..*: * **: . : * *: : :* * : *::** *:: ** :*::***********::.:::.::*: * .. *::*: ***::**:** * . *:*.*.:*.. :.:* * . . :* :*:* : : :* *: :: : . *: :. . ***: :* :: : :: ::.**** **::. :: ::.: *:.*****: *** :: *: :*:**:***:**:* : .:. ::*:****: ...** *** *:** . *:.**.* **..* ** :*:.:: : .**:**:* **. :.: * * :** .:.:* :::: : :* *:*.**:.*.**: *::: :* : ::* **.:** * ::::******* . ::***. .**:*******: .:* :**: :* .. :*. *:: *:*:. :* : .. ", "identical_positions": 200, "similar_positions": 324, "identity": "9.78%" }, { "cls_id": "homologset.agr.MGI:2138986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A338P6K9-1", "uniprot_id": "QSER1_MOUSE", "id": "A0A338P6K9-1", "name": "Glutamine and serine-rich protein 1", "aln": "MDAHYAPAGFAEPPAPPASAATQPAAPAWAYEAR---------VPAAASSPSCSGSSPSLKASYEDGHPSQSESDVLQRQTF---------------TASHQLPGYATTPQATGMHSSAATELFVAGPLPTTGTLPPP-TLSAYQHSSTFSNRNFATTSPLVLQDSSFNTTSNGILSPHDPLLQIKTSQGTVPTALAFERLGSSALSNSVPPQSSTYRSAQESAPHLLQPQFSLLPSTLGGAQQTPQAYNSALFPSSAASIERALLRECSVIKHHQRPSVTQSIQAQLTG-SQHPLHSYLSSAS-IGNFQEPSRQSSLSCSSVRDSTQVSNGVLPQKTPQVSAELAQSYSSVIPSSGYLPSA---TKVDSCSTKQPLTSTTIPKPQSVIPPVQTLNYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGLVQPHNVPSIVHSQVYRSSRVEKLPSLYKTLT-FSGSSQPVTSENQTLSYSSNQQEVLSLVTN-ENYPAQTRDLPSVSESQNYSSGQSQGLSPVSQTQVSYSSQSQVLSVVSPSESYASGQSLTLTAPSLSYSSASRGQSLPVSTPTPSYTSMHPSPNAQTQGSS-AQPQEFLPAVQSS-FASSTRGQTLQSSIPSPDPKSYAERKLDSSVYTSSKQDE--FPVQKLQALQSQASLESSSQRLPDGEVN----AQESVYKTSKADDRY-SQSVTRNNSHLEDQVVGVALQGSEQEENMVGSMTQLNQQSGQSNNAVATDLKKATNLMQTPQVRLNTKDLNQQHSLMHKMHEAKVQQQHDQIMSASSQIQIPNPALGQSHQA-LPHTSVLLDSACDLQILQQAGILQASLGQAKASLQVQRVQSPQQIVHPFLQMDGHIIQSNGEHPQQQLHPHNSDIMKLDLPEPSKPLQQ-LTTKGPFSEANPHDSKNQFVSLGSICFSEAMLLSDERNILSNVDDILAATAAACGVTPSDFSKSAAN-ETMQDIESSDSKSHYQQSLNVRHVNSDFNSIAASVGKPQSINDISLNGNQVSVSLSSVPTLQSETVLDQPHMETPSQTIPTKVPSAMVGLGQEIQEQSSDPFKKQLTINHESKEDREIAVDSALSNNRNQEFVSNSRSISGDSVVSERDFTLVGDDTGVLVNPRRSTLALLAMPQPGDAASGKTEDEKQDVTYFNLPKEKAKGKEQGK---EEED-NQKQLKRSAQCKRQNPRGTDVYVPYTSPSLESCDEGFQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKCGPKQQFSTLAVRVPNRTRRSGIQTTRTFCPPPFAKTSPAAQA--PSETGGVSLSEKVDSELK-TLEQLSSFSSDEEDPGSCGHDIYKNTSAPLTVLDATSDKTKKTVLEALPVATPGASAETAGVAPTASTAVATIKQD-LHLTSLTVNTMENANSTESPTAIELDSLPSDQLAKGQDTVAIEGFTDEENIESGGEGQYRERDEFVVKIEDIETFKEALNTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKTKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTIRNIPSKPSSISKTSDPPVSKTTTTKTPS----TKPKAKQLKIKAEPPPKKRKKWKEEFSSSQSESSPEVRSSSSEDEGFEPPAPSVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLVNLHLDQPFKNALESFPELTVITRDSKAKSGGSAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKNEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMD6-1", "uniprot_id": "D3ZMD6_RAT", "id": "D3ZMD6-1", "name": "", "aln": "MDAHYAPAGFAESPAPPSSAATQPAAPAWAYEAR---------VPAAASSPSCSGSSPSLKASYEDVHPSQSESDVLQRQTF---------------TASHQLPGYAATPQATGMHSSTAAELFVTGPLPTSGTLPPP-TLSAYQHPASFSNRNFVTTSPLVLQDSSFNTTSNGILNPHDPLLQIKTSQGTVPTALAFERLGSSALSNSIPPQSSTYRSAQESAPHLLQPQFSLLPSTLGGAQQTPQAYSSALFTNSAASIERALLRECSVIKHHQRPSVTQSIQAQLTG-SQHPLHSYLSSAS-IGSFQETSRQSSLSCSSVRDSTQVSNGVLQQKTPQVSAELAQSYSSVIPSSGYLPSA---TKVDSCSTKQPLTSTTIPKPQSVIPPVQTLNYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGSVQPHGVPSIVHSQVYRSSRAEKLPPLYKTLT-FPGSSQPVTSENQTLSYSSNQQEVLSLVTN-ENYPAQTRDLSSVSESQNYSSGHSQGLSPVSQTQVSYSSQSQVLSVVSPSESYASGQSLTLPAPSLSYSSASRGQSLPVSTPTPNYPSMHSSPNAQTQGSSPPQPQKFLPVVQSS-FASSSRGQTLQSSIASPDSKSYAERKLDSNVYTSSKQDD--FPMQKLQALQSQASLESSSQRLPDGEVN----AQESVYKTSKADDRY-SQSVTRNNSHLEDQVVGVGLQGSKQEENMVGSMTPLNQQSSQPNTSVAPDLKKSTNLMQTPQIRLNTKDLTQQHSLMHKMHGAKAQQQHDQMISATPQIQVPNHALGHSHQA-LPNAPVLADSACHLQILQQAGMLQASLGQAKASLQVQRVQSPQQIVHPFLQMDGHIIQSNGEHPQQQLHAQNPDVMKLDLPEPSKPLQQ-LTTN-------PQDSKSQFVSLGSICFPEAMLLSDERNILSNVDDILAATAAACGVTPSEFSKSAAN-ETMQDIESSDSKPHYQQSLDVRHVNSDFNSITATVGKPQSINDISLNGNQVSVNLSSVPTLQSETVLDQPHMETSSQNIPTKVPSAMVGLGQEIQEQSSDPFKKQLTINHESKEDREMAVDSAVTNNRNQEFVSNSRSISGESVVSESDFTLVGDDSGMLVNHRRSTLALLAMSQPGDAASGKTEDEKQDVTYFNLPKEKAKGKEQGK---EEED-NQKQLKKSAQCKRQNPRGTDVYLPYTSPSSESCDEGFQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKCGPKQQFSTLAVRIPNRTRRSGTQVTRTFCPPPFAKTSPAAHALLPSETGGVNLSEKVDNELK-NLEQLSSFSSDEEDSGTCGHDSSKSTSAPLTALDPTSDKTKKTVSETLPVATPGASAETAGVTPTPSSVVGTVKQD-LHLTSLAVNTVENVNSTEPPTAIELDSLPSDQLAKGQDTVAIEGFIDEENVESEGEGQYRERDEFVVKIEDIETFKEALNTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKTKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTVRNIPSKPSSISKTSDPPVSKTTTIKAPS----TKPKAKQLKVKAEPPPKKRKKWKEEFSSSQSESSPEVRSSSSEDEGFEPPAPSVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLVNLHLDQPFKNALESFPELTIITRDSKAKSGGSAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKNEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2KHR3-1", "uniprot_id": "QSER1_HUMAN", "id": "Q2KHR3-1", "name": "Glutamine and serine-rich protein 1", "aln": "-------MNFLS-----------------TAESR---------TAQAAAS------------------------------------------------GTTLLPQFRAPSWQTGMHSSAATELFATGPLPSTGTLPP--SLSAYQHPTTFSNRNFATTSPLVLQDSTFNTTSNGILSHHDPLLQIKTSQGTVPTALAFERLGSSVLSNSIPPQSSTYRSAQESAPHLLQPQFSLLPSALGGSQQTPQAYSSTLFTSSTASIERALLRECSVIKHHQRPSGTQSIQAQLTG-SQHSLHSYLSNSS-VVNFQETTRQSSLSCSPIGDSTQVSNGGLQQKTSQVSVELAQSYSSAIPSSGYPPST---TKIKSCSTEQPLTSTKTPKPQSIIPPVQTLSYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGLVQPHNVPSIVHSQVYRSSKVEKLPPLYKTLT-FSGSSQTVTPENQTLNYSSNQQEVLSSVTN-ENYPAQTRDLSSVSQSQSYSSGHSQGLSPVSQTQVSYSSQSQVLSVVSLSESYASGESLTLTAPSLSYSSASRAQNLPDSSPTQNYISMHSSQNVQTQESSSPQSQKFLPAVQSSSFASSTHCQTLQNNITSPDPKSYAERKLDSDVYPSSKQEDG-FPMQELQVLQPQASLESSTQRLSDGEIN----AQESTYKVSKADDRY-SQSVIRSNSRLEDQVIGVALQASKKEESVVGSVTQLNQQIGQVNNAATLDLKNSTNLIQTPQIRLNTKDLKQQHPLILKVHESKVQEQHDQIINASSQIQIPNHALGHGHQASLPNTQVLLDSACDLQILQQS-ILQAGLGQVKASLQAQRVQSPQQIVHPFLQMEGHVIQSNGDHSQQQLHPQNSEVMKMDLSESSKPLQQHLTTKGHFSETNQHDSKNQFVSLGSMCFPEAVLLSDERNILSNVDDILAATAAACGVTPTDFSKSTSN-ETMQAVEDGDSKSHFQQSLDVRHVTSDFNSMTATVGKPQNINDTSLNGNQVTVNLSPVPALQSKMTLDQQHIETPGQNIPTKVTSAVVGPSHEVQEQSSGPFKKQSATNLESEEDSEAPVDSTLNNNRNQEFVSSSRSISGENATSESEFTLGGDDSGVSMNPARSALALLAMAQSGDAVSVKIEEENQDLMHFNLQKKRAKGKGQVK---EEDNSNQKQLKRPAQGKRQNPRGTDIYLPYTPPSSESCHDGYQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPKQQFSTLAVRMPNRTRRPGTQMVRTFCPPPLPKPSSTTPTPLVSETGGNSPSDKVDNELK-NLEHLSSFSSDEDDPG-YSQDAYKSVSTPLTTLDATSDKKKK--TEALQVATTSPTANTTGTATTSSTTVGAVKQEPLHSTSYAVNILENISSSESSKPIELDGLPSDQFAKGQDTVAIEGFTDEEDTESGGEGQYRERDEFVVKIEDIETFKEALKTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKSKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTIRTVQAKPSSSSKTSDPLASKTTTTKAPS----VKPKVKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEIHTSSSDDEEFEPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLLNLHLDQSFKNALESFPELTIITRDSKAKSGGTAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKDEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9B1-1", "uniprot_id": "E7F9B1_DANRE", "id": "E7F9B1-1", "name": "", "aln": "MERNYPSSSFTEPGSAAAQTAGWAYKPSSSYGSTQLDSELVQRQSFASSHQSTFTTTHHPTGVFDSNQHSTASSNTTESSIMNFLSAIESRSLQAGPAGSTLLPSFRSPSWQTGANSS--TELFLTGALHPSGTFPTPSALSSYQHPSAFPTRSFTTASALGVQDSTFSS-SNGLLSSNDSLLQLKSSQNTVQTALAFS---GTSLGVGLPPQSSTYRSAQESAPHLLQPQFSLLSASLGSSQQAPQPYSGPAFSG---SIERALQRECSVIKHHQRPSSTQPVQEQLANSAQHSLQGYLHDESDVSYQQDLSPHTPVPCSPVGDPSPLNG-----TTQQKTASQTQAYASSVPSPGFSSSTGVKVKDGSSSIAQHPSEDTDSQVQTSSPGLQPQSYSSPTQKQSSVIASQLQPYTSTQLTGLVSVSASHTYITSQSLSN-SLSQTQAFTSSLPEKLPSIYKTLSSFASQSEAETSVSQSHIYSSSQQQDLHPSGNREGYETHVQTHCMGSPSQSYSSSHSQGLP-----TISFYTQG-PASVSIPSQNYVSSQSLTSVP---SFSSN-YSRSLSSSNPGQDYVLMQSSPGSKT--DNALLQQKYLLSVQSSTSSAATYTKVLPKDQSSVEIK---PRQEDEQMFLPSKASSGELPLEDVQALQ-KGSLVTSPQNISTSEIGEQNSAKNDIYVVSKMEDRHNTPSVIRSNSRTEEQTL--------------------SQMENTKELTTNANAKSIPLLMHSSTLAPLSADQLKQHTLLLKGSSSQQQNHHEQIIQVQTTDPRQ-LSEGQAQFIRVPSTTQVLLDPSHMIVLQQP-VLTTAQNQPKQTMYMQSV--PVQYVH--MNSDTVNLTINGRHNQQFVSHQVPNSTGSTKEDPTLKDQS-----------SPHDIKQNFS-LNSVCFSDSMLLADERNILSNVDDILAATAAACGVTPQDFVKSTSSDGDMSSVANPVDSKCNFQSPENRHN--------------------SFPSQHMIINPQAMTVIGAQTTYSKE--ETEGHQVFTLSHSNNQ---PEERCKSAQDISDKVAN---AHEKSDVLSKGRFVNSSNGSLNTNGLAISN---TTSNDFNLANQQQSQSPHHITENVSS-NLSQQKELKGFKTNDSIIENSTDGLAKKRSRSKGSSKQTAEDENGQPKFQKKSIQVKRQNSRANET---STTSASEVSHDNFQQQEKMRQKLKEVEEKQPEVKTGFLGSFLDFLKSGSRQNLSSPPIRSPNRTRKSSASKRPPNPLLIPFKPPPPVTPLISPEPQSVISTKRLDEELQRNLETLPSFSSDEEDSVGKNQDLQKSITSALSSLDEPSDKKQK-------------LGDNVKQLQTSSTQPVVVDQQ---------KSVEKISAED-----LLKDVPTDKLAVQLNAVAIEGLIDEELSDSGGEGMYRERDEFVVKNEDIERLTVTLKAGVEPPAIWKVQKALLQKFVPELRDGKRVFFATNSYLGYFGDAKLMYRRVHVKFLDTVNKREYVRVCSRKPQCKPMHSMRSSQAKALLAQRFAAATASDCATQKTAQQKALSKPKPKQPKAKAEPPPKKRKKWKEEFTSSPSDSSPEAVS---EDDEFTPPVPFASRFLNTRTMKETFKSFVELLVSVALDADVLNALERENDELLLPHMKRVDGMITDNRRRLLPKLRMGQIFKNALDCFPELSVVT--ELKTDCETPVFKVRLSGRAYNKKTMKPSKSPSKLPLEYTVDQQKTKWFSLYHSLQHYKYHTYLMCVEEIELLKSRGRDLGQEETVQTCMGNRSWVEGLFDRFGELLTQVQQACL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . : : . *:: .: ** : :.. ** :** :*** :*.* .:**:*. :**:***.::*..*.*.*:*.* :***:*.: ***:*. :*.***:*:**.** *****. .: *. .:*************************.::**.:**:**.*... *.. ****** ************* **.:* **:. :**.*:.** . * : *: : ::.:.**.: *.: :.. .* * :.. :*:*:* :**.*: .*: .* *.* * :. . .: *: * :*. .**.* ::*****:.* * *:::**..*:*** *:.* *. . *: ::*.: ** ****.:****: *...*:. *. .*: ***.**: * * *.* ::.: * **.***.:****. :*: :*. ** *:.*.*.:*** . *:** .:.*. *.* .* *:.* . :* .. *::* **** :::: :.* .. .* : * *: *..:: .** .. :*::.:*.** :.** :*.*.:. .*:. *::. * .** :**: : ** *.**: *:*.: .* . : :. : *. . *:::. : : * :**.*: * :: *::*:*::.. . : *:.: :* : : ....: :***. :* :. .* * :: * * * * ** :: : : ** * ** : : .: :.: *. :* *.:* *.*:**.:::**:************************ :* **::. *. : . .. ** : ** *: .::: :. ..:..: :: . .: ** .: : * * * : :*: :..: : :.*. : .. . *. * .: :.. :**. .:. :*.* .:: . : . :: :.* : . * ::. : .* *::::.* . * *::: : * *:. * ****.*..: *..: * ..:.:*:*******:**************:.*******.*.:*::*: .:* *****:.. . . *..... . .*. . :.::*.**: .** *.******:*. .:* *. ::.*: ** .***.:* .:.. *.*: .:.*: : :*: .: : *..:*:*::* ::*****: *** :* *** ********** **** :. :*::* *******************:***:* * ************* *:*::***::..**:*******:**: ** :::*. :*. .: : . .*. :* *:.. *** ** * ****************:** *:**** : :*: * **.* .:******:*******::*****:***.*.::***:.**********::***:.***:*** :*::.* *****:.****:::* . .. :.: *:::.*:******::.**:.:* . *::** :* : :******:*****.**:* :**. ::.:..****** ** ** * .***.**::*****.:*** * ", "identical_positions": 650, "similar_positions": 567, "identity": "35.25%" }, { "cls_id": "homologset.agr.MGI:2138987", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AJN7-1", "uniprot_id": "S4A11_MOUSE", "id": "A2AJN7-1", "name": "Solute carrier family 4 member 11", "aln": "MSQNE-----------HCQDSGEYFSAGTQGYFKN------NMEDNLEVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDLEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFALDPNHAEPDCDLDLLMAKLFTDAGAP----------MESKVHLLSDTIQGVTATVRGVQYEQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMM-----MPRAAGHSMSSLHTHRHPQ--------------PPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGH---HYHTKRTSSLVSLLGIGRSPNSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLIGSYGFQEIEMSKFRYNPSESLFEVAQIHS----------LSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVP9-1", "uniprot_id": "D3ZVP9_RAT", "id": "D3ZVP9-1", "name": "Solute carrier family 4 member 11", "aln": "MSQNE-----------HCQDSGEYFSAATLGYFKN------DTDDNPDVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDIEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFAQDPNHAEPDCDLDLLMAKLFTDAGGP----------MESKVHLLSDTIQGVTATVRGLQYEQSWLCIVCTMKSLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMM-----MPRAAGHSMSSLHTHRHPR--------------PPKCKDFFPFGKGIWVDIMRRFPVYPLDFTDGIIGKGKTVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFWKYYYGH---HYHTKRTSSLASLLGISRSPNTSLHTALNTSFLASPIEMTTASSPISTHSNQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLISSYGFQEIEMSKFRYNPSESLFEVAQIHS----------LSFKAISSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVNVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBS3-3", "uniprot_id": "S4A11_HUMAN", "id": "Q8NBS3-3", "name": "Solute carrier family 4 member 11", "aln": "MAAATR-------RVFHLQPCENSPTMSQNGYFEDSSYYKCDTDDTFEAREEILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLFTDAGAP----------MRGKVHLLSDTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPE--------------PPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSA-----THSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQS----------LSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T691-1", "uniprot_id": "A0AB32T691_DANRE", "id": "A0AB32T691-1", "name": "", "aln": "MKTDKDGKDMRGVTVNRFAEEAPSSGMAKNGYFYQ------EMEQREREEHEEGSEEREEGQDSPIPSGDDIHLYG-----SQTHQGGPETDVHGCVLLNTSRRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHVSQDPHTAEPGCNFEEIMSSLFTDAGSQEVNDRSANFIFYDNVHLLSETLQCVTATATGIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKSAESVFSHLVSLSLLCRGPCCRDFFRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAP------TLANGSAAELNRISG----SVHLGELNQTEAGPVSLPES----FILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEG-PVFQVAPLDK----------LTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGHLYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMDAQRM---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53838-1", "uniprot_id": "BOR1_YEAST", "id": "P53838-1", "name": "Boron transporter 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNESTRVTVSRG---------------------------CTASDECAQALERTNDELDRESSVSESRSDEESHEKLSRRR--------------------------------------------------FPTLGIGIWLDLKDRIPYYKSDWVDAFN------YRVIPSIVDTYFNNLLPAIAFAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQILTRQFSAKSGEK-----------------------------------------------------SVQDGFASVVVALVMTAFGLFFKLFHYYPLFSHRIRTFISDYSTALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEPIPVKDVFIALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLLVRDSNQK------VISCVEQRFTNTFQGLMILGTMTRPLLVCLGEIPQAVLSGLFFIMGINGLMTNSIIQRLVFLFSDPNRRDNTSPLMKVSKKSMLIFLSFSLTGFAGEFAITN-TIAAIGFPLVLLLSVLVSFSFAYIFPTEELKILDTNVAQKFTIKNLLLENIRDAKFCDKHED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :** .:: * .::: .:: ...: :::::** :* * :* * .* ** *: *:* * *:.*.: : :.: : *: ***:***.. : * . .*::.: ..::.*:::.: .*.** * .*.*:::: .: * . : .: .* :*. :* : .. * ::. .. :::.***.:.:: ..:: .: * . .::: : .* : *: * : :* :** : .::** :* . . : . . * : :. :. : *: :*::* :*:::::*: :.: : :* * :::*:*: * .: . .::*:* :. *::.**.. * : :.. : .* *:: .:: . :::* * . * **:.** ***: :.:..: *.: .*:.:*:.: . * : :*.::.: * :.: : *: .:. : : : *:: ::.: : * * ** *:: ", "identical_positions": 95, "similar_positions": 223, "identity": "10.1%" }, { "cls_id": "homologset.agr.MGI:2138993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NVG1-1", "uniprot_id": "LPCT4_MOUSE", "id": "Q6NVG1-1", "name": "Lysophospholipid acyltransferase LPCAT4", "aln": "MSQGSPGAWAPLDPTSGSSASPNPFVHELHLSGLQRVKFCLLGVLLAPIRVLLAFIVLFLLWPFAWLQVAGLTEEQLQEPITGWRKTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLEAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYQPSLEESKDPTLYANNVQRVMAQALGIPATECEFVGSLPVIVVGQLKVALEPQLWELAKVLQKAGLSPGFVD-------MGAEPGRSRMISQEAFAQQLQLSDPQTVAGAFSYFQQDAKGLVDFRNVALALAALDGGRSLEELTRLAFELFAEEQAEGSDRLLYKDGFSTILHLLLGSPRPAATTLHAELCQPGCSQGLSLCQFQNFSLHDPLYGKLFSAYLRPP-HKPRSTSQIPNASSPSSPTALANGTVQAPKQKGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZR52-1", "uniprot_id": "D3ZR52_RAT", "id": "D3ZR52-1", "name": "", "aln": "MSQGSSGAWAPLDPTSGSSASPNPFVHELHLSGLQRVKFCLLGVLLAPIRVLLAFIVLFLLWPFAWLQVAGLTEEQLQEPITGWRKTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLEAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYQPSPEESKDPTLYANNVQRVMAQALGIPATECEFVGSLPVIVVGQLKVALEPQLWELGKVLQKAGLSPGFVD-------MGAEPGRSRMISQEAFAQQLQLSDPQTVAGAFRYFQQDAKGLVDFRNVALALAALDGGRSLEELTRLAFELFAEEQAEEPDRLLYKDGFSTILHLLLGSPRPAAMTLHAELCRSGCSQGLSLCQFQNFSLHDPLYSKLFSAYLRPP-HKPRSTSQIPNAS--SSPTALANGTVQAPKQKGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q643R3-1", "uniprot_id": "LPCT4_HUMAN", "id": "Q643R3-1", "name": "Lysophospholipid acyltransferase LPCAT4", "aln": "MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSRLQRVKFCLLGALLAPIRVLLAFIVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLQAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYANNVQRVMAQALGIPATECEFVGSLPVIVVGRLKVALEPQLWELGKVLRKAGLSAGYVD-------AGAEPGRSRMISQEEFARQLQLSDPQTVAGAFGYFQQDTKGLVDFRDVALALAALDGGRSLEELTRLAFELFAEEQAEGPNRLLYKDGFSTILHLLLGSPHPAATALHAELCQAGSSQGLSLCQFQNFSLHDPLYGKLFSTYLRPP-HTSRGTSQTPNASSPGNPTALANGTVQAPKQKGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QD35-1", "uniprot_id": "F1QD35_DANRE", "id": "F1QD35-1", "name": "", "aln": "-----------MLKNKGQTAHP--FIHEVNLTALQRIQGLVLGVFLFPVRITLAVLFFLLMWPIARLRLAGLPESRRAEPVRGWRRWLFHHVMVFLSRAVFFCVGFLWVRVKGRQAGLKEAPVLAVAPHSSFLDMLVLSVTGLPIVVSRSENAKLPVIGALLEFNQSVLVSRKDPESRKKCVSQICERVTSDGHWPQMLMFPEGTTTNGRALIKFKPGAFVAGVPVQPVLLHYCSQPDTVRWTWKGLSWLGALWHTTSQIYSSITVEFLPVYTPSAEEKQNPELYAENVQKLMARALGVPATDYMMEG-FPVQKLGNLSLPLEPPAQETLRLLHQQGFSKSRVESVMKDMIDSCHSGEITMVTADQLTTVLGLEEKQTAAKICSLYSKDD--MVDLRQICLSVSAVSGFWSLESLIHTAFMWFDTDADG----QLSAEDLSSLMGALLGIPQRSITEMYSALTSRGQP---TEASLRDILLTHPTYRKVITEYLHFSGLEDGNHNGLPNGKTNGNNNGIYHG-YRTTNRKTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * .* * *:**::*: ***:: :**.:* *:*: **.:.::*:**:* *::***.*.: **: ***: : *: :: *** :** :*** :**:*::*. :****..****:*:* :** .** ****:** .:*******.***::****:** **:: *.:: .*.**.*:***:*:***** :* :**:*******:*********::* .. **. *:*:* . * .** *:** * : ******* ** **.::* ***:***::**:***:***: : * :** :*.*.:.*** * ::*:: *:* . *: ....*. *:: : :: * *.: **.* :.:* :**:*::.*:::*:.* ***.* : ** * : * :.:*::: *** *: : ::: * * . : ..:::: * .* * *::: **: . . . **.. .. ..: :* ::.::* *", "identical_positions": 207, "similar_positions": 171, "identity": "38.91%" }, { "cls_id": "homologset.agr.MGI:2138994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R2R1-1", "uniprot_id": "POMT1_MOUSE", "id": "Q8R2R1-1", "name": "Protein O-mannosyl-transferase 1", "aln": "------------------------------------------------------------------------------------------------------------------MGSHSTGLEETLGVLPSWLFCKMLRFLK----------------------RPLVVTVDINLNLVALTGLGLLTRLWQLSYPRAVVFDEVYYGQYISFYMKRIFFLDDSGPPFGHMLLALGGWLGGFDGNFLWNRIGAEYSSN-VPIWSLRLLPALAGALSVPMAYQIVLELHFSHGAAIGAALLMLIENALITQSRLMLLESILIFFNLLAVLSYLKFFNSQTHSPFSVHWWLWLLLTGVSCSCAVGIKYMGIFTYLLVLGIAAVHAWNLIGDQTLSN----------------------MRVLSHLLARIVALLVVPVFLYLLFFYVHLMLLYRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLKSVSGKPLPCWLHSHKNTYPMIYENGRGSSHQQQVTCYPFKDINNWWIVKDPGRHQLVVNNPPRPVRHGDIVQLVHGMTTRLLNTHDVAAPLSPHSQEVS--CYIDYNISMPAQNLWKLDIVNRESNRDTWKTILSEVRFVHVNTSAILKLS-GAHLPDWGFRQLEVVGEKLSPGYHESMVWNVEEHRYGKSHEQKERELELHSPTQLDISRN-LSFMARFSELQWKMLTLKNEDL-EHQYSSTPLEWLTLDTNIAYWLHPRTSAQIHLLGNIVIWTSASLATVVYTLLFFWYLLRRRRSICDLPEDAWSRWVLAGALCTGGWALNYLPFFLMERVLFLYHYLPALTFQILLLPIVLQHASDHLCRSQLQR-----------------NVFSALVVAWYSSACHVSNMLRPLTYGDTSLSPGELRALRWKDSWDILIRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99PR0-1", "uniprot_id": "POMT1_RAT", "id": "Q99PR0-1", "name": "Protein O-mannosyl-transferase 1", "aln": "------------------------------------------------------------------------------------------------------------------MGNRSMGREDTLGVLPSLLFCKMLRFLK----------------------RPLVVTIDINLNLVALTVLGLLTRLWQLSYPRAVVFDEVYYGQYISFYMKRVFFLDDSGPPFGHMLLALGGWLGGFDGNFLWNRIGAEYSSN-VPVWSLRLLPALAGALSVPMAYQIVLELHFSHCTAMGAALLMLIENALITQSRLMLLESILIFFNLLAVLSYLKFFNSQTHSPFSVHWWLWLMLTGVSCSCAVGIKYMGIFTYLLVLSIAAVHAWHLIGDQTLSN----------------------ICVLSHLLARAVALLVVPVFLYLLFFYVHLMLLYRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLKSVSGKPLPCWLHSHKNTYPMIYENGRGSSHQQQVTCYPFKDINNWWIVKDPGRHQLVVNNPPRPVRHGDIVQLVHGMTTRLLNTHDVAAPLSPHSQEVS--CYIDYNISMPAQNLWKLDIVNRESNQDTWKTILSEVRFVHVNTSAILKLS-GAHLPDWGFRQLEVVGEKLSLGPHESMVWNVEEHRYGRGHEQKERELELHSPTQHDISRN-LSFMARFSELQWKMLTLKNEDL-EHQYSSTPLEWLTLDTNIAYWLHPRTSAQIHLLGNIVIWTSASLATVAYTLLFFWYLLRRRRNICDLPEDAWSHWVLAGALCIGGWALNYLPFFLMERMLFLYHYLPALTFQILLLPIVMQHASDHLCRSQLQR-----------------NVFSALVVAWYSSACHVSNMLRPLTYGDTSLSPGELRALRWKDSWDILIRKY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6A1-1", "uniprot_id": "POMT1_HUMAN", "id": "Q9Y6A1-1", "name": "Protein O-mannosyl-transferase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MWGFLK----------------------RPVVVTADINLSLVALTGMGLLSRLWRLTYPRAVVFDEVYYGQYISFYMKQIFFLDDSGPPFGHMVLALGGYLGGFDGNFLWNRIGAEYSSN-VPVWSLRLLPALAGALSVPMAYQIVLELHFSHCAAMGAALLMLIENALITQSRLMLLESVLIFFNLLAVLSYLKFFNCQKHSPFSLSWWFWLTLTGVACSCAVGIKYMGVFTYVLVLGVAAVHAWHLLGDQTLSNVGADVQCCMRPACMGQMQMSQGVCVFCHLLARAVALLVIPVVLYLLFFYVHLILVFRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLRNVFGKPVPCWLHSHQDTYPMIYENGRGSSHQQQVTCYPFKDVNNWWIVKDPRRHQLVVSSPPRPVRHGDMVQLVHGMTTRSLNTHDVAAPLSPHSQEVS--CYIDYNISMPAQNLWRLEIVNRGSDTDVWKTILSEVRFVHVNTSAVLKLS-GAHLPDWGYRQLEIVGEKLSRGYHGSTVWNVEEHRYGASQEQRERERELHSPAQVDVSRN-LSFMARFSELQWRMLALRSDDS-EHKYSSSPLEWVTLDTNIAYWLHPRTSAQIHLLGNIVIWVSGSLALAIYALLSLWYLLRRRRNVHDLPQDAWLRWVLAGALCAGGWAVNYLPFFLMEKTLFLYHYLPALTFQILLLPVVLQHISDHLCRSQLQR-----------------SIFSALVVAWYSSACHVSNTLRPLTYGDKSLSPHELKALRWKDSWDILIRKH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QF89-1", "uniprot_id": "POMT1_DANRE", "id": "F1QF89-1", "name": "Protein O-mannosyl-transferase 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MQCVK----------------------LPVSVTVEINVLLLAVTALALFTRLYGIHFPKAVVFDEVYYGQFLSLYMKQVFFIDESGPPFGHMILALGAYLGGFDGNFVWNRIGAEYPGN-VPVWSLRLIPALAGSFCVPLAYLVVVELGYSHFSALGACALLLMENSLIVQSRFMLLESVLIFFLLLAVLSYLRFHKARN----SFFKWFWLVICGVSCAFGIGVKYMGMFTYFLLLSLAAVHTWQLIGDQTLSHG----------------------KVMFQVLVRFLALVVLPVIMYLGFFYIHLTLLYRSGPHDQMMSSAFQASLEGGLARITQGQPLDVAFGSQVTLRTVSGKPVPCWLHSHKANYPIRYENGRGSSHQQQVTCYPFKDVNNWWIIKDPGRQSLVVSSPPKPVRHGDIIQLLHGMTTRYLNTHDVAAPMSPHSQEVS--GYIDFNVSMPAQNLWRVDIVNRESEKEIWKTILSEVRLVHVNTSAVLKLS-GASLPEWGFKQLEVVGDKIYKGYQQTGMWNVEEHRYGRSQEPKERELELKSPTHSDVNKN-LTFMAKFLELQWKMLTVKNEES-EHKYSSSPLEWITMDTNIAYWLHPSSNAQIHFIGNIVTWTTGNITLVVYCLLFLTYLLRRRRKVEDIPQDSWEQLVLAGVVCLGGWAVNYLPFFLMEKTLFLYHYLPALTFKILQIPIVTEHLYIHVLRSSAQQ-----------------KAFGGVILAVLCSVYMSYHSLSPLTYGQPALTSDKLAELRWRESWDILLRKR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTK2-1", "uniprot_id": "POMT1_DROME", "id": "Q9VTK2-1", "name": "Protein O-mannosyltransferase 1", "aln": "MSATYTNTITQRRKTAKVRQQQQHQWTGSDLSGESNERLHFRSRSTNSMQQHTAISNSPSPLCCNGARALTMLNCCVDVNCHLNAPLRGSVNRHTTPTPTPTATPTPVATPKQASPSPTSDRSRSLSRSPSPSRSRSLSCQKQIDKNSAGAASAEERKTANASSQPFTVNLRIDLFSWTLFLLAFGTRFYKLATPPHIVFDELHYGKYISMYMRNIFFFDQH-PPLGKQLIAGLVSLAGYDGNYTFTRIGEPYSPE-MPIFWFRFLPAMCGSLLAPAVYNLLLEAKLSRWSSALGGLLVVLDNSLLTQSRFVLMESMLLLATTVGIACLLRFQRSRLG---SLEWFFTGTAAAVCLGAAGTVKYVGFLALGLAFYLLCRHLWQLLYDAGLTDR----------------------QLWMHAISRLLIFVGIPLAVYLGVFYIHFKTLHRAGPHDSIMTSAFQASLDGGLASITKGQPLAVVHGSQITLRHTHGR--TCWLHSHAAVYPVRYPDKRGSSHQQQVTCYSFKDVNNWWLVKRPTKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMTPQCQEVS--CYIDYEIKMAGELLWRVEILNRDSEGDIWHAIKSEVRLVHVSTEASLKFS-GRQLPEWGFNQHEVVADRE-KAIHEDAIWNVEEHRYTQTEDHRERERQMLTAEMIPTKRTRISFWAKLLELQSKMLFQTKSVP-NHMYSSMPHEWPLMDKGIAYWLDSQSSAQIYLLGNILLWYTATMGILVYAGLLAFYAMRRQRLCFDISEQEWQRFVLAGDTFFMGYVMHYIPYFCVDRTLFLHNYLPAFVFKLLLLCFVVEHLDYLLRRFCTGRGVHLV------------RLYRLMLILWLVGVLSIFSKFIPFSYGARKMTLNEVRSLRWKDTWDFVLHKNHHLY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46971-1", "uniprot_id": "PMT4_YEAST", "id": "P46971-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 4", "aln": "------------------------------------------------------------------------------------------------MSVPKKRNHGKLPPSTKDVDDPSLKYTKAAPKCEQVAEHWLLQPLP-------------------------EPESRYSFWVTIVTLLAFAARFYKIWYPKEVVFDEVHFGKFASYYLERSYFFDVH-PPFAKMMIAFIGWLCGYDGSFKFDEIGYSYETHPAPYIAYRSFNAILGTLTVPIMFNTLKELNFRAITCAFASLLVAIDTAHVTETRLILLDAILIISIAATMYCYVRFYKCQLRQPFTWSWYIWLHATGLSLSFVISTKYVGVMTYSAIGFAAVVNLWQLLDIKAGLSLR---------------------QFMRHFSKRLNGLVLIPFVIYLFWFWVHFTVLNTSGPGDAFMSAEFQETLK------DSPLSVDSKTVNYFDIITIKHQDTDAFLHSHLARYPQRYEDGRISSAGQQVTGYTHPDFNNQWEVLPPHGSDVGKG---QAVLLNQHIRLRHVATDTYLLAHDVASPFYPTNEEITTVTLEEGDGELYPETLFAFQPLKKSDEGHVLKSKTVSFRLFHVDTSVALWTHNDELLPDWGFQQQEINGNKK--VIDPSNNWVVDEIVN----------LDEVRKVYIPKVVKPLPFLKKWIETQKSMFEHNNKLSSEHPFASEPYSWPGSLSGVSFWTNGDEKKQIYFIGNIIGWWFQVISLAVFVGIIVADLITRHRGYYALNKMTREKLYGPLMFFFVSWCCHYFPFFLMARQKFLHHYLPAHLIACLFSGALWEVIFSDCKSLDLEKDEDISGASYERNPKVYVKPYTVFLVCVSCAVAWFFVYFSPLVYGDVSLSPSEVVSREWFDIELNFSK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :.: :*:: : * :****:::*:: * *:.. :*:* **:.: ::* * *:**.: : .** * . * * : *: *:: .* : : * :. . *: ::.: :.::*::*::::*:: : . ::* ..: : :: .:. . **:*.:: : *:*: . : * :: :*. :** *::*: : :** * :*:: ** :*. . .: . . : : .:**** ** * : * ** **** *.. *.** * : * .: . : .: ::* * * * :****:.: * :*:: : : .: : *: .: ::: .: . :: ..*:.**.*.. * . **:**:.* *: .:: . * *:* : . :.* : * * *: .. :* ::* * .* ..:::* . . **:::***: * : : : : *:* : : : . .: :*:*:* : : **::**** : * : : : : .:: .. : *: ** :: :: .* : . : ", "identical_positions": 126, "similar_positions": 220, "identity": "13.52%" }, { "cls_id": "homologset.agr.MGI:2138997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CJ52-1", "uniprot_id": "PROM2_RAT", "id": "Q8CJ52-1", "name": "Prominin-2", "aln": "---------------------------------MTRTLDLMVPLLGLSLGLALSLPRAVAADCGSLGRVEHLAFAPVPGTE--------------PTAPRVRAPWPLDSLYGTVRRFLSVVQL------NPFPAELIKTLLNDPSS-------VKTDEVVRYEAGYVVCAVIAGLYLLLVPITGLCFCCCRCRRRCGGRVKT-EHKAMACERGTLMTFLLLTTLMLLIGMVCAFATNQFTHSQTGPSVEAVPETLLSLRGLVSDVPKKLQAVADQFSSPQKQVSKDLDGVGENLGNIIHNQLKSTVYPVLASVHGLGQALQVSIDHLQSVNATSVELREGQQHLGPPVQAHRERLLALLQESWCHEN-CKGALSQASALQLG----ADFSQMPPVDDVLHRLQGVPEANFSSMVQEENATFNNLPILVHMQMVSVVKDLKKALAEQPEGVRMLAQAFPGSEATSRWSQALEGLEQRSRPYLQDVQRYETYRWILGCVLCSAILLVVICNLLGLSLGIWGLFAREDPSHSETKGEAGARFLMAGVAFSFLFAAPLILLVFATFLVGGNVQTLVCRSWESGE---LYEFVDTPGNLPPSMNLSYLLG-LRKNISVFQAYRQCKAGTALWKVLQLNDSYDLDKH--LDIKQYTHELQQELQSFKVDLKDLDLLNPAARQNLEALQSSGLEKIHYRDFLVQIQKPVVKTDMGQLAKELEGLAQAQNESLR---RQQLQEEARELRSLYQEKVVPQENLVAKLNPSIRVLESSAPKLQVNTSDLLDIVAR----LKGELPAQLNHILRNATECFLTREMGYFSQYVTWVREEVTQHIATCQPFSKALDDGHMILCDMMANPWNAFWFCLGWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSE---------------ETQLFHIPRVTSLKL------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UUY6-1", "uniprot_id": "PROM2_MOUSE", "id": "Q3UUY6-1", "name": "Prominin-2", "aln": "---------------------------------MTRSPGLMVPLLGLSLGLALSLPEAVTDDCGSLGRVEHLAFARVPRTR--------------ELAPLVRASGPLNSLYGTVRRFLSVVQL------NPFPAELIKTLLNDPSS-------VKTDEVVRYEAGYVVCAVIAGLYLLLVPITGLCFCCCRCRQRCGGRVKT-EHKAMACERGTLMIFLLLTTLVLLIGMVCAFATNQHTHSQTGPSVKAVPETLLSLRGLVSDVPEELRAIAEQFSVPQKQVSKELDGVGENLGNVIHNRLKSTVYPVLASVHSLGQALQVSIDHLRALNTTSVELQEAQRHLEPPVQAHRERLLALLQDSWCHEENCKRVLSQAGALQLG----ADFSQTPPVDDVLHRLKDVPETNFSSMVQEEKATFNNLPLLVQVQAVSVVKDVKKALAEQPEGLRMLAQAFPGSEAASRWSQALEGLEQRSRPYLQEVQQYETYRWILGCVLCSAILLVVICNLLGLSLGIWGLFAREDPSHSETKGEAGARLLMAGVAFSFLFAVPLILLVFVTFLVGGNVQTLVCRSWESGE---LYEFADTPGNLPPSMNLSYLLG-LKKNISIVQAYRQCKAGAVLWKVLQLNDSYDLDKH--LDIKQYTHKIQQELQSFQVDLKELDLLSPTARQDLEALQRSGLEKIHYRGFLVQIQKPVVNTDMWQLAQELEGLAQAQNDSLL---RQQLREEARELRSLYQEKVVPQESLVTKLNFSVKTLESLAPSLQVNTSDFLDSVTR----LKGELPVQINHILRNATECFLTREMGYFSQYVTWVRAEVTQRIATCQPFSTALDNGHVILCDMMADPWNAFWFCLGWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSE---------------ETQLFHIPRVTSLKL------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N271-1", "uniprot_id": "PROM2_HUMAN", "id": "Q8N271-1", "name": "Prominin-2", "aln": "---------------------------------MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARAR--------------WLAPRVRAPGLLDSLYGTVRRFLSVVQL------NPFPSELVKALLNELAS-------VKVNEVVRYEAGYVVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKT-EHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARCQGD-CAGALSWARTLELG----ADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCQSWENGE---LFEFADTPGNLPPSMNLSQLLG-LRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEEH--LDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVL---GQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTY----LKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSE---------------ETQLFHIPRVTSLKL------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8X9-1", "uniprot_id": "F1Q8X9_DANRE", "id": "F1Q8X9-1", "name": "", "aln": "----------------------------------MKSRTKAVSWSGVLLLVLRTCASGQQSCLVEKMRPELQTPNETQSQL--------------TLNSAFMTP--------IVHSFLGLVQP------NPFPKDLLVRMINNFNSN---TQTEMVKEVLNYEKGFLVCVAIGILYIVLMPLIGLIFACCRCCGNCGGRMQQKQTSSTNCKRRSIYCSTFIITVLILAGNICMFLSTTYTSETVKSSSNEITGILDDVKGYVSSIPQQIQQVLDESFLTVDQVKNNLNETGPLLGGLIQNGLKDSLNPAFNSITQIAQVINSTSTGLLHVNETLGQLKPKIDALKTNFSAVRQRINNTMNQPECMNCSSLQQVVDKLSLEGS----LEFSDQNDLSSAVDKAR---NADVIGQANKGRDFFDSIPQKVKNETQGSVESALSKLNDIKGQISGVSKDLP-LDFLKTIPKEISTLQQSVSVYSPEVERASLISRAIGLILSCLILLVVVCNFLGLLLGAVGLNAKQSPTDRSGTSNCGGVFLMVGVGFSFLISWIFMLVVLILFIVVGNTYTLVCVPWQSKQ---LIQIIDTPG-MIPGFNLSKNLN-LKISLNIYDIYSNCEQNAPLWTTLHLNELVDLNKY--LNVSNYTQEIYQSFEAAQINIANITILSPDIKSQLNNFSNS--ASTMNFSTIIQHINDVSGTNLSSAADSLDFLAGKQSNQNI---SNQLHGEAKDLRDIQADITSNIMPLLLELNSTINNLSAVASQINASVQNVLQNVGY----AQEILNYNISQIVRAESKVFVDCQMKIFLAYIQWANQTITGNVGRCRPAAAAIDRTENLLCKHLVGSLNAFWFSLGWCMLFLIPSIILSVKLAKYYR--RMKYSDVYEN---------------NNLPMHPFPKANLKPEFVENAKQ----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P82295-1", "uniprot_id": "PROML_DROME", "id": "P82295-1", "name": "Prominin-like protein", "aln": "MGEVAATVEPLAAVKSKSMRSRKRRQRRRRQIAYLAICGLSVAIFGFALATLIRPTTAQADADPGSWRKGYVGHGTTHEQLGQPHWPPVQYTVYRPTTNYTKAPPPPTSAMNPIFNFTHFLYDKVLYRDEPIPEGYIVVKNSDTLSLGPKVEENDWRDLLAHYWMVLIWVVILVVLIIVIPFIAVCYCCFCCCRRCRQGCPPCTSKQDAQRRFCCGICLLILIIGLIFGIIIAFVTNKMIDSGFAETSETMKRGSEDTCTYLKDVADHVHHLMMYN--YEEMETHVLDQLTHAHRHIFLDLSDTSESNSLAEMERVLENMPEALELMRQVEKMEKDLRFYGSQLRDGVRGIKRDVNFAVAN-LCQLQMCQKFLISSNIEHIDSSQCLHFDNLPNTKEFVEGMENIVASEYYAIPQRGLSRLKKVSDKVKTQLSFVVPPMMRDLTKGRTIFREHATNVRNIVEGVLSDIHIKTLHS-TKSFEDVYERFGHDRNVVSLIVCLLILLVLFILIFALLCGCFGR-RRTGYGDECCSKSTGATCLLLAILLIFCVFSFIALVGLFYFMLGMVTYQGACAPLRDQENNTLFRQLDASIDLNHYLPPSESNKEVVQPLKMSSAIKACHANQTIFDMMRQHNIYDINDLTRIKVMSHSQENTDSIKVFDEDLSTVVLLTKEERDELKTAGESKLAKYHSSLYMPSLCTQFTPMNLNALSEQLYKLSNDLEYPAYGWAKVSFWNEGLNTKAFYRNFVPKLTSLVEKMKANLKKIDELISYENHDFTNTIKILTATAINSEQFIQTRGKDYINALGGNLTNSIDQMIDDYIDMIIKEANESVGHCAPLSYIYYRGVDLICHRIVDPINGFWVGILLCALLFLPILFVAHRLMCLYKKIYPYLATVGAAGVVEGGSDYLYDAYSERDREHVPLANVPKKRRKAYERRREQQDYFEDASPSVSRGNRSGGDRGGGGGDGAPGSSSMRYNDMAPTHWDHEPPRYHNPPAAPPSSEYERPPPYYYPGASEQD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *. * . . :. : * .: :*:* : .: * ::: : :: ..* : ::::* .: :.* * .* . .* :: : :: * : * :. . : : : . :..:...:: : . .. *: : : : : : : : : : :: :*: * . : : : : * . : . . .*.: . :. . :: . :. :. :. . : * : . . : . :. :.. : :: :. ::. :*:*:. ::.* * * : . . . . *. *: .: : * . : *: : *:: . .* . .. : * . *:. : : * : :.: . *. . :: :: :: *::. :.: .:::: :.:: . : : :*. : :*: * : . . .: :..* *: . : *. : : : . *: ::: .:. :. . : . : : : : : :. : : *: . :. * * : ::*. :... *.**. : * ::::* ::.: : :: : . : * * ", "identical_positions": 54, "similar_positions": 256, "identity": "5.3%" }, { "cls_id": "homologset.agr.MGI:2139014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXR9-1", "uniprot_id": "OSBL6_MOUSE", "id": "Q8BXR9-1", "name": "Oxysterol-binding protein-related protein 6", "aln": "MSSDE-KGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSSTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKAR-RIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYR-QNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQ--------------------PNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEE-----MDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWR---TKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPN-LCADI-EFQTPPSHLTDPLESSTDYTK------LQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSES---TICDHVVSVNIIPSPDEPGEQ---IHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LMF4-1", "uniprot_id": "A0ABK0LMF4_RAT", "id": "A0ABK0LMF4-1", "name": "Oxysterol-binding protein", "aln": "MSSDE-KGISPAHKTSTPTHRSALSSTSSQRESRQSIHVLERTASSSTEPSISRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKAR-RIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYR-QNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQ--------------------PSSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEE-----MDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWR---TKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPN-LCADI-EFQTPPSHLTDPLESSTDYTK------LQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSES---TICDHVVSVNIIPSPDEPGEQ---IHANLPLSQQVVNESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKELLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZF3-1", "uniprot_id": "OSBL6_HUMAN", "id": "Q9BZF3-1", "name": "Oxysterol-binding protein-related protein 6", "aln": "MSSDE-KGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKAR-RIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYR-QNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQ--------------------PNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEE-----MDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWR---TKSVSKDTKIQLQ-------------------------VPFSATMSPVRLHSSNPN-LCADI-EFQTPPSHLTDPLESSTDYTK------LQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSES---IICDQVVSVNIIPSPDEAGEQ---IHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJS4-1", "uniprot_id": "A0A8M2BJS4_DANRE", "id": "A0A8M2BJS4-1", "name": "Oxysterol-binding protein", "aln": "MSRHQSRTTSLEEKVATPIHR----STAPLQKSSTPTHKSASSSSSSQRDSR-------------QEPDSWEIIEGLRIGQTHVQRPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPVDIQKGKLHGSIDVGLSVMSIKKRAR-RIDLDTEEHIYHLKVKSPDVFDLWVCKLRHHRLFR-QNEIVRSPRDATLRTFPPSAGAESPQNTPSSTHPKKQGK-------------------PSSFPWQLPPSCSN--------GQSKVAAWLQESEE-----MDKCAEELAYCQSSLLELNQLLQSLEILQRTQSAPNFTDMQSNCVDLSKKEKRVSRRWR---TKSVSKDAKLQQQVQS--------------LPQSHSAKVPLSASMSQVRLHSSNPN-LCAELADFQAPVTRLTDGIDSAGDYIK------LQEDFCIIAQKVHSLLKSAFNTVAIEKEKIKQVLLDHEQ-TGQSNQIVTLRRSLSQALSQNAELKTRLNRIHSES---VLSEQVVSVNIISSPDEACEP---LHVGLPLSQQVSNESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YVSDVSDNISEDNASVTDNVSRQMPNGELASSMFRNGRRPCLPAPAPDTSNINLWNILKNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAQTDDPYERMAIVAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPISACHCDSQNFTFWQDVRWKNKFWGKSMEILPIGTVNVMLPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTRSTTCICKLSFIKGNYWSSNVNEVQGSVMDQEGRVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAVELNELFPEMKELLPPTDARFRPDQRFLEEGNVQMATAEKQRIEEQQRNRRKWMEENNIKHQPRFFKKVMDSNQRERWVSNSMYWELRKDPGFLKLENPELW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38713-1", "uniprot_id": "OSH3_YEAST", "id": "P38713-1", "name": "Oxysterol-binding protein homolog 3", "aln": "METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKLKSSVDDHASAVHIAPDTKTLLDYTTKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKRKERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQGDLEVKDTDYYYAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDKIIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPDILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYR-DKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLAN--ETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERR----NKGQDVEPKYFEKVSK-NEWKYITGPKSYWERRKKHDWSDIS--QLW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : * : . : .. ** : ..* . : : ::..:*. : . * : :.. : .: *: : . :: :. :* :. .: :::. :: * : :.. . : * : : . :*: : *.*.:. .. : :.: . : . .* : * : :. .:: :* * . :. : .. :: *: * : *. : *: ..:*.* .: . :: :. : ..:. : **...: : *. . :: *.. .*: : : :.. : :.. : : . *. **: :*: . . .* * :. . .: : : *. **. .:. :* .:* ** : :. *.:. ** .:. * ** : :..* ::..**.: .. . : . .: .:::. ::. :. : . :* . : :. * . :* .* .:*::*:*****.::*** ***:. ** :.* :**: ** **:: ** : .* :* * *: *****:*.**:* **** ** ::**:***:**: * ..: :: : .:******:*: * :.: : . *: : *.: ** ::*:::*.*::* .*. ::.::. . : *: :*. ...: * *** :.* .: : **. *.: :: : ****:*: :***: * *****:*:*** * ****:: * * ::*: **.** ::. . *::*:** . *: : .. . *** **. .: .:. **", "identical_positions": 175, "similar_positions": 318, "identity": "17.4%" }, { "cls_id": "homologset.agr.MGI:2139018", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08635-1", "uniprot_id": "SAST_RAT", "id": "P08635-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "METAVNAKSPRNEKVLNCLYQNPDAVFKLICFPWAGGGSIHFAKWGQKINDSLEVHAVRLAGRETRLGEPFANDIYQIADEIVTALLPIIQDKAFAFFGHSFGSYIALITALLLKEKYKMEPLHIFVSGASAPHSTSRPQVPDLNELTEEQVRHHLLDFGGTPKHLIEDQDVLRMFIPLLKADAGVVKKFIFDKPSKALLSLDITGFLGSEDTIKDIEGWQDLTSGKFDVHMLPGDHFYLMKPDNENFIKNYIAKCLELSSLT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R197-1", "uniprot_id": "SAST_MOUSE", "id": "Q8R197-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "METAVYAKSTRNEKVLNCLCQKPDALFKLICFPWAGGGSTHFAKWGRKINGLLEVHAVRLAGRETRFEEPFSNDIYQIAEEVVTALLPIIRDKAFAFFGHSFGSYIAFITALHLKEKYKMEPLHIFVSSASAPHSEFRPQVPDINKLSEEQIRDHLLIFGGTPKHLIEDQDFLKQCIPLLKADVDIVKKFIFDKPSKALLSRDITCFIGSEDVVKDIEGWKDITSGKFDVLKLPGDHFYLMEPNNEDFIKNYIVKCLELSSLDYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV23-1", "uniprot_id": "SAST_HUMAN", "id": "Q9NV23-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "MERGDQPKRTRNENIFNCLYKNPEATFKLICFPWMGGGSTHFAKWGQDTHDLLEVHSLRLPGRESRVEEPLENDISQLVDEVVCALQPVIQDKPFAFFGHSMGSYIAFRTALGLKENNQPEPLHLFLSSATPVHSKAWHRIPKDDELSEEQISHYLMEFGGTPKHFAEAKEFVKQCSPIIRADLNIVRSCTSNVPSKAVLSCDLTCFVGSEDIAKDMEAWKDVTSGNAKIYQLPGGHFYLLDPANEKLIKNYIIKCLEVSSISNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40ECQ8-1", "uniprot_id": "A0AB40ECQ8_DANRE", "id": "A0AB40ECQ8-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "---MWNILSRGMDKVITCFNKCPDASVRLICFPWAGGGSIHYARWAKTLPSSIEVYSVRLPGREGRTKEPFFQNMQEILDEVIGVLLPQLKEKPFALFGHSFGAMICFAFAEHVKKVHNLEPIHMFLSGASAPYSEARLQAPRRSHLSDDEFLIWVTSIGGTPPEILANAELAKLFLPALKADLYVADSYRCSRPSKPFLSCPVSCFDGKEDSPHDLQAWKIMTSGDFTVQMLPGSHFYLKEAANEKYILDIITKHIETAEMDYL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::.*: : *:* .:****** **** *:*:*.: . :**:::**.*** * **: ::: :: :*:: .* * :::*.**:****:*: *.: * :*: : **:*:*:*.*:. :* : * ..*::::. : :**** .: :. : * ::** :. . . ***..** :: * *.** :*::.*: :***. : ***.**** .. **. * : * * :* :.: ", "identical_positions": 83, "similar_positions": 92, "identity": "31.32%" }, { "cls_id": "homologset.agr.MGI:2139054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWZ9-1", "uniprot_id": "GP107_RAT", "id": "D3ZWZ9-1", "name": "Protein GPR107", "aln": "MAVRVPLGCTGS------FCPRLLPLLALLELLVDPSLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNISSLSVNEPEGVKDKDTEIGFSLDRTKNDGFSSYLDEDVNYCILKKK--SMSS--VTLLILDISGSGVKVRSP--------------------------------------------------------------------------------------------------PEAGKQLPEIVFSKDEKVPSRSQEPAVSSNPKDSKVQRTPDGSK-----------AQRSTVDSKTIAEKFFSIHKNDGA------------------------------------------------------------------VSFQFFFNISTSDQEGLYSLYFHKCP----SSKLRSGEQVSFSLNIDITEKNPDSYLSAGEIPLPKLYVSMALLFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGK------------------------------------------------AAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKFAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEDDLEMESVVTTS-GVMENMKKVKKVSN-------------GAVEPQGSWEGTA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUV8-1", "uniprot_id": "GP107_MOUSE", "id": "Q8BUV8-1", "name": "Protein GPR107", "aln": "MAVPVPLGRFGS------FCLRLLRLLALLELLVHPVLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNVSSLSVNEPEGATDKDAEIGFSLDRTKNDGFSSYLDEDVNYCILKKK--SMSS--VTLVILDISGSIVKVRSP--------------------------------------------------------------------------------------------------PEAGKQLPEIVFSKDEKILSQSQEPAVSSNPKDSEARRTLDGFK-----------AGRSTVDSKAITERSFSIHKNDGV------------------------------------------------------------------VSFQFFFNISTDDQEGLYSLYFHKCS----GNNVKPGEQASFSLNIAITEKNPNSYLSAGEIPLPKLYVSMALFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGK------------------------------------------------AAINLAKLRLFRHYYVLIVCYIYFTRIIAFLLKFAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEDDDLEMESVVTTS-GVMENMKKVKKVSN-------------GAVEPQGSWEGTA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VW38-1", "uniprot_id": "GP107_HUMAN", "id": "Q5VW38-1", "name": "Protein GPR107", "aln": "MAALAPVGSPASRGPRLAAGLRLLPMLGLLQLLAEPGLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNVSSLSLNEPE---DKDVTIGFSLDRTKNDGFSSYLDEDVNYCILKKQ--SVS---VTLLILDISRSEVRVKSP--------------------------------------------------------------------------------------------------PEAGTQLPKIIFSRDEKVLGQSQEPNVNPASAGNQTQKTQDGGK-----------SKRSTVDSKAMGEKSFSVHNNGGA------------------------------------------------------------------VSFQFFFNISTDDQEGLYSLYFHKCL----GKELPS-DKFTFSLDIEITEKNPDSYLSAGEIPLPKLYISMAFFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKGDSMGPLQQRANLRAGSRIESHHFAQADLELLASSCPPASVSQRAGITAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKLAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEEDLEMESVVTTS-GVMESMKKVKKVTN-------------GSVEPQGEWEGAV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASE9-1", "uniprot_id": "A0A8M3ASE9_DANRE", "id": "A0A8M3ASE9-1", "name": "", "aln": "MAS----GKMCM----------FTVINVIIIVLVIESQCRIHHLVLKDDIRQRVHLNTFGFYKDGYMSMNMSHLSFTGGKMDNIDSSTIGFSLDRVNNNGFSTYLDEGLDYCPLKKDPSSSFA--GVLLLLDFKHNLVKKKTS--------------------------------------------------------------------------------------------------AETG------VFPKIMAVPPKKSEEVQVEKGKEPQNKEPDDGSQSKA--------ASKSKRDAENKAEDTYPLQYEDNG------------------------------------------------------------------YSFQFYFNVTTDEQQGLYNFYFYNCYSLPMNQESSVSDMLPFSIEITIKEKNPESFLSAGEIPLPKLYICMSIFFFLIGILWVHVLRTHSADVYKIHWLMAALPFTKSLSLIFHAIDYYYISNQGSPIEAWAVVYYITHLLKGALLFITIALIGTGWAFVKHILSDKDKKVFMIVIPLQVLANVAYIIIESTEEGSSEYGLWMEILFLVDLLCCGAILFPVVWSIRHLQEASATDGK------------------------------------------------AAINLAQLKLFRHYYVMIVCYIYFTRIIASLIKVIVPFQWKWLYQLMNELATLTFFFLTGHKFRPASYNPYLLLSVEDEDMEMDDVAMTSTAIGEGLKKVKKVSN-------------GPSEERESMA----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W366-1", "uniprot_id": "Q9W366_DROME", "id": "Q9W366-1", "name": "GOST seven transmembrane domain-containing protein", "aln": "--MWAPGGDVKS--------IVVLAALTALLWAPLEVLGRKHHLEVRNDRRQYIALSTFGFYTNGHLDVQLSKLTFDNEQ----STDLMGLSLDKTTIDQLNPYLDSHQNKCILEESPKSQISGPILFFVLDLKELKVRVKCSPEWHNMHIYNQIPSRTKRHSHMAKVSDSVLFRQTRAAQDFSAEGPDESMEDPLEQEPTDLKSSSPAAVAGKIELPKDEGAPKVDAPAQNVDAVKEESVPKPEVAANQNISDKQELPPPPNAAPKVEEAVKSEQKQEEAPAEKDETPSKKEETPAKQVSVEEPKVAAPPLAVNSPAAAPSLDDTEVDKKNEATDTDAAPGNPFPHEGDSEEDSYGPDSFKQSQENLCKDSTMPLVRETINNVHYYSFNFSMMVATPSDEGLYNLYFHACP--------NYHTSKIMSFNVDIEENNNGNYLSAGEMPLPALYFMMSLLFFLSGLFWVFILKKSKHTVYKIHYLMAVLVFLKSLSLMFHSINYHFIEKRGEHVETWAILYYIAHLLKGAVLFITIVLIGTGWTFIKHILSDKDKKIFMIVIPLQVLANVAQIITDESDQSDAEFRTWHNIFFFVDLLCCGAILFPIVWSIRHLHEASATDGK------------------------------------------------AAINLRKLKLFRQFYIMIVCYIYFTRIIVDLLQMTVVFQYAWLDEMFREMATYVFFVLTGYKFRPVSSHPYFTVPDEDEDDDEVEVLTES-GLTETVHRVKQLNRNHGSGLGGITIIEGNDDERENLIAKRESSHEYD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : * *** :::* *: : *.****:.:*:: :::* *:. : . :*:***:.. : :..***. : * *::. * :.:**:. *: : . .:. : : . : :. . : : : . : .:: **:* : ::* .::***.:**: * :*::: * *:* .:*****:*** **. *:::*** * .*:.:*:. *:***:***.* * *****:**:*:*::*..:* :* **::***:******:*****.******:*:**********:************** ** :.:::. :*: * : :*:************:*******:******** ***** :*:***::*::***********. *::. * **: ** ::: * ** .**.***:****.* :**: :. *::* : .* * .: * :::**::.. * : : . ", "identical_positions": 209, "similar_positions": 159, "identity": "25.83%" }, { "cls_id": "homologset.agr.MGI:2139080", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A039-1", "uniprot_id": "DZAN1_RAT", "id": "D4A039-1", "name": "Double zinc ribbon and ankyrin repeat-containing protein 1", "aln": "MTAGSVCAPQIIPLRVPQPGKANHEIDTNTLLEMKSDTPDVNIYYTLDGSKPDFLKKVGSGENNTFKYIKPIALPDGKIQVKAVAVSKDCRQSGIVTKVFQVDYEPPKMVSSEDHGED-ALKGFSKQELKNGFVGPKLRKKYKNAENKSTWNVNLRRLADLKVGERADPKTLKDLRFSESPLEIPAYHEGASARLPTHQAQSPGFAHITG-QKSLTSTEVMRIQRETDFLKCAHCLASRPSDPFARFCQECGAPVPPIFGYRLPPPEGAQMGLCAECGSMVPMNTPICVVCEAPLAPQLRPQASLYLKERVICRTCGTGNPAHLRYCVTCEGTLPPTQEQWLCNGDEVPRLPTRNGETISCSRCGCQNLWEASFCDWCGAMLGISASHSVCPKCGASNHLTARFCGSCGIYVKSITRFRMNNSLAIVAGGPRPFPEPRSAWQSLNVPLPTPATGSKKDMGTQTSGLFYPSGKLLAKKELEAASHRQRQEKMSDHRPVLTAVSPGRGYWRKQLDHISAHLRSYAQNNPEFRALIAEPRMGKLISATVHEDGYEVSIRLNYIQVSNKNLYLNKSMNLSDHFLSSVTEGGNGLYGSRSSLVSAYSQSISDTPESIKKMKNPKAKSFLANPEPLTPENRLLLEEVGSTGKGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHFEAIPVLAQRGADIDQQWGPFGNTALHEATLLGLEGRESVATLLGCNANTQKKNTRGQTAYDIALEMGDDLTSALFAD-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C008-1", "uniprot_id": "DZAN1_MOUSE", "id": "Q8C008-1", "name": "Double zinc ribbon and ankyrin repeat-containing protein 1", "aln": "MTAGSVCAPQIIPLRVPQPGKANHEIDTNTLLEMKSDTPDVNIYYTLDGSKPDFLKKVGSGENNTFKYVKPITLPDGKIQVKAVAVSKDCRQSGIVTKVFQVDYEPPKMVSSEDNVED-ALKGFSKQELKNGFVGPKLRKKYKNAENKSTWNVNLRRLADLKVGERADPKTLKDLRFAESPLEIPAYHEGASARLPTHQAQSPGFAHITG-QKSLTSTEIMRIQRETDFLKCAHCLASRPSDPFARFCHECGAPVPPIFGYRLPPPEGAQMGLCAECGSMVPMNTPICVVCEAPLAPQLRPQASLYLKERVICRTCGTGNPAHLRYCVTCEGPLPPTQEQWLCNGDEVPHPPARNGETISCSRCGCQNLWEASFCDWCGAMLGISASHSVCPKCGASNHLTARFCGSCGIYVKSITRFRMHNSLAIVAGAPRPFPEPRSAWQSLNVPLPTSASGSKKDTGTQTSGLFYPSGKLLAKKELEAASHRQRQEKMSDHRPVLTAVSPGRGYWRKQLDHISAHLRSYAQNNPEFRALIAEPRMGKLISATVHEDGYEVSIRLNYIQVSNKSLYFNKSVNLSDHFLSSVTEGGNGLYDSRSSLVSAYSQSVSDTPESIKKMKNLKAKSFLVNPEPLTPENKLLLEEVGSSGKGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQWGPFRNTALHEATLLGLEGRESIATLLGCNANAQKKNTRGQTAYDIALEMGDDLTSSLFAAKFTQGLEDQLSPPGNRILGDS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVP4-1", "uniprot_id": "DZAN1_HUMAN", "id": "Q9NVP4-1", "name": "Double zinc ribbon and ankyrin repeat-containing protein 1", "aln": "MTAGSVCVPQIIPLRVPQPGKANHEIDNNTLLEMKSDTPDVNIYYTLDGSKPEFLKRIGYGENNTFKYIKPITLPDGKIQVKAIAVSKDCRQSGIVTKVFHVDYEPPNIVSPEDNVEN-VLKDSSRQEFKNGFVGSKLKKKYKNSENQRSWNVNLR-------------------KFPESPLEIPAYGGGSGSRPPTRQSQSPGFAHVSG-QKCLTSTEIMRIQRETDFLKCAHCLAPRPSDPFARFCQECGSPVPPIFGCRLPPPEGAQMGLCAECRSLVPMNTPICVVCEAPLALQLQPQASLHLKEKVICRACGTGNPAHLRYCVTCEGALPSSQES-MCSGDKAPPPPTQKGGTISCYRCGRWNLWEASFCGWCGAMLGIPAGCSVCPKCGASNHLSARFCGSCGICVKSLVKLSLDRSLALAAEEPRPFS------ESLNIPLPRSDVGTKRDIGTQTVGLFYPSGKLLAKKEQELASQKQRQEKMSDHKPLLTAISPGRGYWRRQLDHISAHLRCYAQNNPEFRALIAEPRMGKLISATVHEDGCEVSIRLNYSQVSNKNLYLNKAVNFSDHLLSSAAEGDGGLCGSRSSWVSDYSQSTSDTIEKIKRIKNFKTKTFQEKKEQLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAAKFGQGLEDQLAQTRSLSLDDC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXR6-1", "uniprot_id": "DZAN1_DANRE", "id": "Q1LXR6-1", "name": "Double zinc ribbon and ankyrin repeat-containing protein 1", "aln": "MTAGSVAAPQIIPIRIPPPGKAKHEIDSSTPVEIKSESPDVRVLYTLDGSKPELTKRPGFADS-TLKYTEPVRLPVGKVYVKAMAISIDGRQSAVVTKVFVVEPSASDERELNAHDEDDSVKNDTAIDGKDVVENGTGVSSVKYLDISS--NEAHR-------------------ALKGPRFLSQRLGPGSSARLTAQNSQNQSADVVESPLKNLTNTQISRIQRETDFLRCPKCLSHRPSDPFARFCLHCGAPVPPIPGQRLPPTEGGQMGLCMHCKTMVPLNTAICVVCESPLDQQLQPQATLRLQDKFICHSCGTGNPAHITHCVTCESQLLR-QARPVLSGQRAAPVPSSQGKMVSCSKCNRVNHSDARFCDWCGAKPGHKASSVKCSQCGASSHPYANHCGGCGVFLDGPPRMPLQVNQRQDAEEMQQTAS----AAELATAPPSVGLRMCADAQTQTVGLFFPSNTELKKRSQQREAELSRQEQMRDRKPLLTAISPGRGFWRKQLDHICAHLRSYTQNNTEFRALIGEPRLGRMISAVIQEDSYEVSLRINFISAPPE-ESRSSSAGQRSRSVTSESQNLSSVTEGRNSASPEN--NINTTGSEVKKKKKKKIGTSDVTENQPESKDSLLLKEVGPEGRGRIPAVQQLLDEGADPACLGKDGRPALVAAVLNGHHDVIPVLVQREADVNQASGPLKNTALHEAAALGDEGLKSVEILLGCNASIRKQNDRGQTPYDIAVAAGSSSVLSLMAAHLGQGLLLRHTKARSLSGLDTFS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******..*****:*:* ****:****..* :*:**::***.: ********:: *: * .:. *:** :*: ** **: ***:*:* * ***.:***** *: .... . : : *: :*. : : *: . . . .. * : . * * : . : *:.:* .::::*. . : . * **.*:: *********:*.:**: ********** .**:***** * ****.**.***** .* ::**:**.******:** **:***:* *:::.**::********: :*****. * * : .*:... *: :* :** :*. * :* **.**** * *. *.:****.* *..**.**: :.. :: :. . * : . .* . * * *** ***:**.. * *:. : :. .***:* *::*:***:*****:**:*****.****.*:***.******.***:*::***.::**. ***:*:*: ... : ..: . .: ::* ::. ..: .*.* . . . * ..:*: *: * : . : .:: ***:***. *.**:..::********* * ..:.**.: .**:* *.:.****.** **::* **: *******: ** * :* ******. :*:* ***.**:*: *.. . :*:* ", "identical_positions": 313, "similar_positions": 225, "identity": "40.03%" }, { "cls_id": "homologset.agr.MGI:2139083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6U6-1", "uniprot_id": "A0ABK0M6U6_RAT", "id": "A0ABK0M6U6-1", "name": "", "aln": "MSLEFGSVALQTQNEDEEFDKEDYEREKELQQLLTDLPHDMLDDELSSPERRDSDCSVDGIAGELYPSEHLERKWIERDILPKPHGVN-------------CGNGWEENRSEPEDQRLGYHPGEG-DEGGSGYSPPGKQEQADLYRLPEDFRPYTGRQKQ-----AASVITFSDPQRDSFQQFGLSQGPNCQALEPC-KAIYKPYP-SSVQKTSPPAQEIAGSDMFEGLQQQFLGANE-NSAENIHIIQLQVLNKAKERQLDSLVEKLNDRERQIRYLNHQLLIVQDEKDGLALSLRESQKLFQSGKEREMQLEAQIHALETQIEAFKVSEEKLTKKLRTTEITLESLKQQLVELHHSESLQRAREQHESVVAGLTQKYEEQVSCLQKNLDTTITALQEQVTWFPMSNCQWSKVGYFVLSEEDVCTRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVHEVTQLQLQLQQAQKAHILSESMNKALQEELTGLKEEISLYESAAELGVLPGDVEGDLSVELTESCVGLGIKNVSWKQSKANSVAQQEPPNEKLSKDEVILKLKTQVQRLLSSNSMKRHLVSELQRDLRDCRETMEALQQSKDSDR--GMETKTETSEKTTNQLWLDSPE-AINREDILRLKNEVEVLQQQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVDRCERTYQQHHEAMKAQIRESLLAKHAAEKQHLSEVYEGTQSQLRSDLDKLNKEVAAVQECYLEVCREKDELESTLRKTMEKAQEQTRQLLEDREEHVRKLKLELEERYQETLKAEKQSWLKAQAAGAT-QVEHESRQKLIQQLEEEWQSKLNHSLPARRKATSDCGSQTDQAAYPAAMPNAEA-LVLAEEQAHQVQ---QEKELTVKEALRKSEVELELKYCESIAQKVETAVQNARSRWILELPMLAEYKALLRAQQQEWAKQQEVAVAHRLSLALSEAKEKWKSELQNMKPNVASVQELEEKIHSLQKELELKDEEVPVAVRAELAKARNEWNKEKQEEIHKIQEQNEEDYRQFLEDHRNKINEVLTAAKEDFVKQKTELLLQKETEFQACLDQSRKEWTLQEAQRTQLEVHRYEEDILTVLDFLLRDTQLEYDGDSQGKQLLEVMSVCSSKWTSVQYFEKVKACIHKALQDTLSLLIDNIASEREKRNVVKTSADAVSWNTGQGDSGVPAPLPVSTSGPCAQSSALLEAEAETDKK-IFEMKDLCCGHCFQELEKEKQECQDLRRKLEKSRRHLQHLERTHKATVEKLGEENSRVVEELIEENHDMKNKLETLRALCRTPPQSLSAGAAESARLLCSGQALEELRGQYIKAVKKIKRDMLRYIQESKERATEMVKAEVLRERQDTARKMHKYYLSCLQQILEDNGKEEGAEKKIMSAASKLATMVGLLGTIAESGCRVSCAQAG-HSALPLASEMLTGVERSERSDVSQNTPHYVESKPNSGKTIPRSVCEQWPRRKAEPSSQRRLEDWKHREVKPMTSTTLPSDCQCGDGSCRHSDNLAKDVAPEFLPCRGEGGFDLQ-KKEALG-AGSESLLYSVNTHSFLGGAEKKLSPRLT---SES--VHTTLRGPREIPKSKPFVCGSLTETESVATEKSQGVGSQDTPVKDGVGPSGSPAWPPD-STLPCGSPAVLFLGDRSQRTQEMLGDSVRRKQFSAPTCLSDAQKGNTVCRSS-----YTLDLPREALRSQQGRMGATLGPSSPQSTDVLKTDFRKPSGTGPASLCQKPLIKLTAPVTGQQDSGFDSPLVNLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AUM9-1", "uniprot_id": "CE152_MOUSE", "id": "A2AUM9-1", "name": "Centrosomal protein of 152 kDa", "aln": "MSLEFGSVALQTQNEDEEFDKEDFEREKELQQLLTDLPHDMLDDELSSPERHDSDCSMDGRAAEPHPSEHLERKWIERDILPKPHSMN-------------CGNGWEENRSKTEDQHLGYHPGEGGDEGGSGYSPPGKREQADLYRLPEDFRPYTGGSKQ-----AASVITFSDPQRDNFQQFGLSRGPSCGALEPY-KAVYKPYRNSSVQKNSSPAQEVAASDMFEGLQQQFLGANETDSAENIHIIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKLTKKLRTTEITLESLKQQLVELHHSESLQRAREHHESIVASLTQKHEEQVSSLQKNLDATITALQEQ---------------------ESICTRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLQLQQAQKAHVLSESMNKALQEELTELKDEISLYESAAELGVLPGDSEGDLSIELTESCVDLGIKKVNWKQSKANRVTQQESPDEDPSKDELILKLKTQVQRLLTSNSVKRHLVSQLQSDLRECRETMEAFQQSKDGDS--GMETKTDTSEKTTKQLWLESSE-AINREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTYQQHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVACPAAVSKAEAAAVLAEEQARQVQ---QEKELATKEALRKPEVELELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQELAVAHRLSLALSEAKEKWKSELENMKPNVMSVKELEEKVHSLQKELELKDEEVPVIVRAEVAKARTEWNKEKQEEIHKIQEQNEEDYRQFLEDHRNKINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRKEWTLQEAQQTQVEIRQYEEDTLTVLAYLLKDTQLEYGGDSQDKQLLEAMSACSSKWISVQYFEKVKACIQKALHDMLSLLTDSVASEQEKRKVVKSSADTVSWTSSEGDSAVPVPLPDSTSVRCAQSSAWLKAEAETDKK-ICEIKGLRCGHCFQELEKEKQECQDLRRKLEKCRRHLQHLERTHRAAVEKLGEENSRVVEELIEENHDMKNKLEALRALCRTPPRSLSAGAAESAGPSCSRQALEELRGQYIKAVRKIKRDMLRYIQESKERAAEMVKAEVLRERQETARKMRNYYLSCLQQILQDNGKEEGAEKKIMSAASKLATMAELLGTIAESDCRVRCAQAGRSVALPLASEMLTGTERSERSGVNHNIPHYVESKPNSGKTLPRSVCEQLPGRKAAPRSQRRLEESKHREMRPMASTALPSDCRCGDASCRHSGVLAKDVAPEFVPCQGEGGFDLHEKRDALG-AGSEPLLYSA-AHSFLGGAEKNSSPRCI---SES--RHTTLRSPSEMPRLKALMCGSPTETDSIASEKSQGVGSQDSPVKDGVGPSSSPAWPSD-STLPCGSPAVLFLGDGSQRTQEMLGDSVQWKQFSATSCHPDAQKSNMVCRSS-----HTLDLPKETLHSQQGKMGATLGHPSPQSTDMLKTDFKRLSGTGPSSLCQKPLIKLTAPMPSQQDSGFDSPLE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94986-4", "uniprot_id": "CE152_HUMAN", "id": "O94986-4", "name": "Centrosomal protein of 152 kDa", "aln": "MSLDFGSVALPVQNEDEEYDEEDYEREKELQQLLTDLPHDMLDDDLSSPELQYSDCSEDGTDGQPHHPEQLEMSWNEQ-MLPKSQSVNGYNEIQSLYAGEKCGNVWEENRSKTEDRHPVYHPEEGGDEGGSGYSPPSKCEQTDLYHLPENFRPYTNGQKQEFNNQATNVIKFSDPQWNHFQ------GPSCQGLEPYNKVTYKPYQ-SSAQNNGSPAQEITGSDTFEGLQQQFLGANE-NSAENMQIIQLQVLNKAKERQLENLIEKLNESERQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESIVMGLTKKYEEQVLSLQKNLDATVTALKEQ---------------------EDICSRLKDHVKQLERNQEAIKLEKTEIINKLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQKAHAMSANMNKALQEELTELKDEISLYESAAKLGIHPSDSEGELNIELTESYVDLGIKKVNWKKSKVTSIVQEEDPNEELSKDEFILKLKAEVQRLLGSNSMKRHLVSQLQNDLKDCHKKIEDLHQVKKDEKSIEVETKTDTSEKPKNQLWPESSTSDVVRDDILLLKNEIQVLQQQNQELKETEGKLRNTNQDLCNQMRQMVQDFDHDKQEAVDRCERTYQQHHEAMKTQIRESLLAKHALEKQQLFEAYERTHLQLRSELDKLNKEVTAVQECYLEVCREKDNLELTLRKTTEKEQ----------------------------------------------QTQEKIKEKLIQQLEKEWQSKLDQTIKAMKKKTLDCGSQTDQVTTSDVISKKEMAIMIEEQKCTIQQNLEQEKDIAIKGAMKKLEIELELKHCENITKQVEIAVQNAHQRWLGELPELAEYQALVKAEQKKWEEQHEVSVNKRISFAVSEAKEKWKSELENMRKNILPGKELEEKIHSLQKELELKNEEVPVVIRAELAKARSEWNKEKQEEIHRIQEQNEQDYRQFLDDHRNKINEVLAAAKEDFMKQKTELLLQKETELQTCLDQSRREWTMQEAKRIQLEIYQYEEDILTVLGVLLSDTQKEHISDSEDKQLLEIMSTCSSKWMSVQYFEKLKGCIQKAFQDTLPLLVENADPEWKKRNMAELSKDSASQGTGQGD-------PGPAAGHHAQPLALQATEAEADKKKVLEIKDLCCGHCFQELEKAKQECQDLKGKLEKCCRHLQHLERKHKAVVEKIGEENNKVVEELIEENNDMKNKLEELQTLCKTPPRSLSAGAIENACLPCSGGALEELRGQYIKAVKKIKCDMLRYIQESKERAAEMVKAEVLRERQETARKMRKYYLICLQQILQDDGKE-GAEKKIMNAASKLATMAKLLETPISSKSQSKTTQSA----LPLTSEMLIAVKKSKRNDVNQKIPCCIESKSNSVNTITRTLCEQAPKRRAACNLQRLLENSEHQSIKHVGSKETHLEFQFGDGSCKHLNSLPRNVSPEFVPCEGEGGFGLHKKKDLLSDNGSESLPHSA-AYPFLGTLGNKPSPRCTPGPSESGCMHITFRDSNERLGLKVYKCNPLMESENAASEKSQGLDVQEPPVKDGGDLSDCLGWPSSSATLSFDSREASFVHGRPQGTLEIPSESVKSKQFSPSGYLSDTEESNMICQTMKCQRYQTPYLSEETTYLEPGKISVNCGHPSRHKADRLKSDFKKLSSTLPSSVCQQPSRKLIVPLSSQQDSGFDSPFVNLD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:****** .******:*:**:********************:***** : **** ** .: : .*:** .* *: :***.:.:* *** ******:.**:: *** ** **********.* **:***:***:*****. .** *:.**.***** : ** **.* .*** *. **** **.*:...****::.** ************* :****::***************:.*:***:: ***:***.***:*::******:*******:***.*****:****** ***:*::*::*.**:: ** ****::*********:************:***:* .**:*:**** .******:*:***:** *.:*:******:********::*****:**:******:**************:**:***:********* :* .********** **:*********:**: *.* **:*.:***** *.****:*.**:**.. :.*:* *:*. ****.*****::***** ***:******:** **::*::.:* ::* *..: :****:****..:*** :*. : *:*** ****::***:*******:* ***.**************:********* **************:*********** ***:* *.** *: ****:***:***::************** ** ***** ** * *.:.: ::*******:******:.:: * :* * * ****:*.: . .:.: * :: *::. * ***::: * *::* *:*****:** *:::** *****:.**: *** ****:**::*:*::* :*:*::* :*:*:*:***********:**: *: . :*****:**********:***** :***:****.***********:******:******:**********:******:***:*********:*:******:***:***:: *:*: :**** **** ** *** *: .**:.***** **.***** *******:*.**:**::* *.** :. .* :**::.: * *:.* :.:** * .:: **. * :***:*** : *:*.* ********** *******: ****. ********.*:*.***:****.:*********:******* *::**:***:****** *.* ** *************:*** *************:************:*****::*** ******:*:*** *******.********. ** * .* .: :*:. ***:**** ..::*:*..*.:: * :***.** :*:.*::*** * *:* ** **: :*:.:: : *. : : **.**:* . *.::*:***:**.*****.*: *:: *. ***.* :*. ::.*** :: *** *** * *:*.. * * *.. *::. *:*****:. *:.***** . *.. .**.. :**. .* . *: . .* * *: .:**: ****.. .*:::.* :*:: * *..*: : *::... * .* :.:* **:**:: *.* *:*:**:* ** .*:..*********: ", "identical_positions": 1042, "similar_positions": 407, "identity": "57.92%" }, { "cls_id": "homologset.agr.MGI:2139090", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATX5-1", "uniprot_id": "A0A8I6ATX5_RAT", "id": "A0A8I6ATX5-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MFPRRPP---------------------------------------ATLAAWLAGARGGG-----------LLAALANQCRFVTGLRVRRAQQIAQLYGRLYSESSRCALLGRFWRRLRGRPGHASALMAA-LSGV---------FVWDEERIQEEELQRSINEMKRLEEVSNIFQSSGVESHPPETKCPAEGNEKSK-------------------------------------------DKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDAVSGSE--VLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHTATL-----KAKNMEIKVKDYISAKPLEMSSEAKATASSPERKNEGSCGPARIEYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1R3-1", "uniprot_id": "STAR7_MOUSE", "id": "Q8R1R3-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MFPRRPP---------------------------------------ATLAAWLAGARGGG-----------LLSALANQCRFVTGLRVRRAQQIAQLYGRLYSESSRCALLGRFWRRLRGRPGHASVLMAA-LSGV---------FVWDEERIQEEELQRSINEMKRLEEMSNIFQSSGVENYPPEPKSPAGGNEKSK-------------------------------------------DKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDAVSGSE--VLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATL-----KAKNMEIKVKDYISAKPLEMSSEAKATAPSPERKNEGSCGPARIEYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQZ5-1", "uniprot_id": "STAR7_HUMAN", "id": "Q9NQZ5-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MLPRR------------------------------------------LLAAWLAGTRGGG-----------LLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGRLWRRLHGRPGHASALMAA-LAGV---------FVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHHPPEPKAQTEGNEDSE-------------------------------------------GKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSE--VLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATL-----KAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVX5-1", "uniprot_id": "A0A8N7UVX5_DANRE", "id": "A0A8N7UVX5-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MFPSVQHRPVCSIGARAVRLQSISSFSNSGAKSSKSFRFSWLGERVGLLMSWLQKAGRGTNKLASDNKKEKLLSIFANHCSFVTGQRLRRAFQIGELYSNLYSERTRWTLVGSIWRRLQSKHAPTGKLVAA-LAGV---------FMWEDEKIRDDELRRCAWELQAVESVRSQDVSPKVATH-----------------------------------------------------------VDQGWEVVMEKKNFRVWRRPVEGSHLFEYRVFGSYTDVTPRQFFNVQLDTEYRKKWDALVIRLDVVDRDVNTGTE--VVHWATHFPYPMYSRDYVYVRRYQVDLENNLMILVSRAVKHPCVPETQEFVRVHSYQSKMVIRPHRSFDENGFDYLLTYSDDPQTVFPRYCVSWMVSSGMPDFLEKLHTAAL-----RAKNMDVSVHDYVNVVKPSQPSQEQRLG----AENTHTAGSSQIYA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJZ2-1", "uniprot_id": "Q9VJZ2_DROME", "id": "Q9VJZ2-1", "name": "START domain-containing protein", "aln": "----------------------------------------------MLFNRFVLAIKNQS---------RETLRAWSYQCESIFAQRSRRVQQLFSFYQSVYGTQGLKQLWRAYYRRELQPPLRGMVMSAVGLVGLNIKRMGSDGFDWNKERLALSNFDLCRRDIEFINALPNNQLCDRCQAKKMKYCYCQLGNQRCKKGQSQPSTSKEAETDPDTSISNCLRPLDLDVRNAPAGTVRIQAQDDQKWEPYFSKNEFSIWRRQER-SSLYSYKVYARFDDITADDFLHVQTDLDYRRQWDDTALRLELISEDPVPGSNSHLIYWEMQWPRLFANRDYVYCRRYIKDDNKKLIFICNRGATHNTYPALSGKVRVTDYWSLMVIKPFRGFHEPGLHFVLTYFDDPGIPIPQNIKSWVTQKQMPEFLTKMYVATKNYACSRAIKMKDMFHGFALINDEYTANEQRGSWLGSLSRRKVNSKPEAGR--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * : :* : . * **. *: .:* :*. * :** : *. * *: * *:.*:: .:: . ::: :: : . . :: ** :.*:.* :*** : *:.*:*:. : *:*. :*::** * :**::** .::*:::..* .*:: :::* ::* : .***** *** * :::::.: .*.. * * *** .* * ***:*.:.*.* *:.::*** *:* :*: **:... **:** *:: *: :* :*. .:.: ..: : .. .. . ", "identical_positions": 82, "similar_positions": 120, "identity": "16.98%" }, { "cls_id": "homologset.agr.MGI:2139134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U309-1", "uniprot_id": "GT253_RAT", "id": "Q5U309-1", "name": "Probable inactive glycosyltransferase 25 family member 3", "aln": "-----------MLFIIRARACGGDARSWK---QPDQLHPILFTNLRLPLQLIASSAG------------GATDHNVDNTTGMLQEWLAAVGRDYATVVWKSEDEARSYPDEQGPKHWTRERHQFLMELKQEALAFARDWGADYILFADTDNILTNNQTLRLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLVSLQTEETARLAFYP-----------PHPNYTWPFDDIIVFAYACQAAGVSVHVCNDHRYGYMNVGVKPHQGLEEEK---TNFIHLILEALVDGPPMMASAHVSRPPKKPSKMGFDEVFVISLARRPQRRARMLSSLWEMEISARVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVAKGLARVVVFEDDVRFEDNFRKRLERLMEDVLTQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAHFWPRDLQAFSARPLLASPTHYAGDTEWLSDTETS------SPWDDDSGRLISWTGSQKTLRGPYLHLAGSSGHSLHPHPRDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KGW5-1", "uniprot_id": "GT253_MOUSE", "id": "A3KGW5-1", "name": "Inactive glycosyltransferase 25 family member 3", "aln": "---MHVARLLPLLLLLGQQLRAASVTEPT---LPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTGMLREWLAAVGRDYATVVWKPEEEARSYPDEQGPKHWTKERHQFLMELRQEALAFARDWGADYILFADTDNILTNNQTLKLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLLSLQTEETARLAFYP-----------PHPNYSWPFDDIIVFAYACQAAGVSMHVCNDHRYGYMNVVVKPHQSLEEEK---TNFIHLILEALVDGPPMLASAHVSRPPKKLSKMGFDEVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGHTLTKGEVGCFLSHYSIWEEVVARGLARVVVFEDDVRFKDNFRRRLERLMEDVLIQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAYFWPRDLQAFSARPLLASPTHYSGDAEWLSDTETS------SPWDDDSGRLISQTGSQKALRGPHLHLTGSSGHSLHPHHRDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T4B2-1", "uniprot_id": "GT253_HUMAN", "id": "Q5T4B2-1", "name": "Inactive glycosyltransferase 25 family member 3", "aln": "MRAARAAPLLQLLLLLGPWLEAAGVAESP---LPAVVLAILARNAEHSLPHYLGALERLDYPRARMALWCATDHNVDNTTEMLQEWLAAVGDDYAAVVWRPEGEPRFYPDEEGPKHWTKERHQFLMELKQEALTFARNWGADYILFADTDNILTNNQTLRLLMGQGLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRRGCFRVPMVHSTFLASLRAEGADQLAFYP-----------PHPNYTWPFDDIIVFAYACQAAGVSVHVCNEHRYGYMNVPVKSHQGLEDER---VNFIHLILEALVDGPRMQASAHVTRPSKRPSKIGFDEVFVISLARRPDRRERMLASLWEMEISGRVVDAVDGWMLNSSAIRNLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVARGLARVLVFEDDVRFESNFRGRLERLMEDVEAEKLSWDLIYLGRKQVNPEKETAVEGLPGLVVAGYSYWTLAYALRLAGARKLLASQPLRRMLPVDEFLPIMFDQHPNEQYKAHFWPRDLVAFSAQPLLAAPTHYAGDAEWLSDTETS------SPWDDDSGRLISWSGSQKTLRSPRLDLTGSSGHSLQPQPRDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5F8-1", "uniprot_id": "A0ACD6B5F8_DANRE", "id": "A0ACD6B5F8-1", "name": "", "aln": "-MLSWIITIWTFLAVVQCYFSEENYTEESKMQPPTVVIAIIARNAAHSLPHYLGALERLNYPKERISVWAATDHNIDNTTAMLREWLTVMQTQYHYVEWRPSDKPTSYAGELGPKHWTNGRYEYIMKLKQAALNFAKKRWADYILYSDTDNILTNPDTLHLLMAENKSVIAPMLDSQSAYSNYWCGITPQGYYRRTAEYFPTKQRQRLGCYPVPMVHSTVLLDLRKQGTRKVSFHP-----------PHKDYSWPFDDIIVFAFSCRVSEVQMYLCNKERYGYLNVPAKPHQTVEDDR---INFVHLYLESLIHGPPMYVSRYVHVPPKQSDLMGFDEIYLINLRRRQDRRDRMLWSLYELEIDAKVVDAIDGAALNSSDIKILGVDLLPGYYDPFSGRTLTKGEVGCFLSHYYIWKEMVDMQLDKALIFEDDVRFQANFKRRMMRLMEEVEQVELDWDIIYLGRKKVNPGEEVPVENVRNLVFADYSYWTLSYAISLQGAQKLLNAEPVSKMLPVDEFLPIMYDKHPNEDYKSHFPNRNLMAYSTHPLLVQPCHYAGDAEWVSDTETS------TLWDDDSVR-TDWRGSHKTLKGSQPPPGLQS-----ATYKDEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPK4-1", "uniprot_id": "GLT25_DROME", "id": "Q8IPK4-1", "name": "Glycosyltransferase 25 family member", "aln": "--MNKQVIFGLLLACILVCISGQDEEDYQ--ESPTVLIALLVRNKAHILPMFLSYLEQQDYPKERIAIWLRCDHSNDDSIELLRQWLDNSGDLYHSVSYEFKPEEQSFVNGTSPYEWPASRFKHLIALKEEAFQYGRDIWADYVFFLDADVLLTSKDSLKVLTRLQLPIVAPMLISESLYSNFWCGMTEDYYYRRTDEYKEIYHVKKQGSFPVPMVHTAVLVNMNHRAVRNLTFDRNKLVELQKSRQQEPLYDGPADDIIVFAISANSSGIPLHICNDITFGYILQPLEPGDTLDHDVQQLVNLKSIMVNELGAVPPLLDYYKHLEKKPEKSKLSLDRIFMINLKRRPERREKMERLFDEIGIEAEHFPAVDGKELSTERLLEMGVRFLPGYEDPYHHRAMTMGEIGCFLSHYNIWVMMVRKQLKEVLILEDDIRFEPYFRQNAVRILNQARN-AAQYDLIYFGRKRLKEESEPAVENADNLVHAGYSYWTLGYVISLQGALKLLAAKPLDKLIPVDEFLPLMFDRHPNKTWTEAFPKRNLVAFSASPLLLYPIYYTGESGYISDTEDSQQISVETSEEGEARLKSDREQVFDHEQEFKLNPELKLGESLSKSHQEL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . . * : .:: * * . **. *:: :*::** * * :. . : : . .* .*. *.:.:: *:: *: :.:. ***::: *:* :**. ::*::* .::**** *:: ***:***:* : ***** ** : :: *.: *****::.* .:. . . .::* . * * ******* :.. : : :::**. :**: :. : ::.: *: : :: * * : . . :.:*.:::*.* ** :** :* : *: *... . *:** *.:. : :** :**** **: :::* **:******* ** :* * ..:::***:**: *: . *::::. .:*:**:***::: .* .**. .** *.******.*.: * ** *** ::*: :::*******:*:*:***. :. * *:* *:*: *** * :*:*:: ::**** * : :.:: . . : . :: ", "identical_positions": 166, "similar_positions": 186, "identity": "26.86%" }, { "cls_id": "homologset.agr.MGI:2139135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EWF8-1", "uniprot_id": "F7EWF8_RAT", "id": "F7EWF8-1", "name": "Anaphase-promoting complex subunit 2", "aln": "MEAEGVAVS-VAAAAAATTTIVATDDCDSRPGQELVVAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRAHGLHSVLEEWFVEVLQNDLQGNIATEFWNAISLRENSV-DEPQ-CLVLLLDAFGLLESRLDPYLHS-----LELLEKWTR--LGLLMGAGAQGLREKVHTMLRGVLFFSTPRTFQEMVQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQQCWCRQALEQFNQLSQVLHRLS--LLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVG-WLGKVFLQ----DNPSRPTSPEAGNT-------LRRWRCHVQRFFYRIYASLRIEELFSIIRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKVALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPACLETGQDSEDDSGEPEDWVPDPVDADP----AKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSP-EREIRNVELLKLRFG-----------------------------EAPMHFCEVMLKDMADSRRINANIREEDEKRPVEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALDVYCKKYEKLKNWRLEPGLLVWLLTTCLPGMALVQVIGARAIPCWVAWYRTYALFIWTCLEPTGLFLMIPAQAMRTLSWKHTLGLVTMDVELADRTLS-VAVTPVQAVVLLYFQDQA----SWTLEELSKVVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRD--NMVLIDSDDESDSGMASQADQK-EEELLLFWTYIQAMLTNLESLSLERIYSMLRMFVMTGPALAEIDLQELQGYLQKKVRDQQLIYSA-GVYRLPKNCN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZQ7-1", "uniprot_id": "ANC2_MOUSE", "id": "Q8BZQ7-1", "name": "Anaphase-promoting complex subunit 2", "aln": "MEAEGVAVAAAAAAAAAAATIIASDDCDSRPGQELLVAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQGNIATEFWNAIALRENSV-DEPQ-CLGLLLDAFGLLESRLDPYLHS-----LELLEKWTR--LGLLMGAGAQGLREKVHTMLRGVLFFSTPRTFQEMVQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQQCWCRQALEQFNQLSQVLHRLS--LLERVCAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVG-WLGKVFLQ----DNPTRPTSPEAGNT-------LRRWRCHVQRFFYRIYATLRIEELFSIIRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKVALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPACLETGQDSEDDSGEPEDWVPDPVDADP----VKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSP-EREIRNVELLKLRFG-----------------------------EAPMHFCEVMLKDMADSRRINANIREEDEKRPVEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALDVYCKKYEKLK-------------------------------------------------------------AMRTLSWKHTLGLVTMDVELADRTLS-VAVTPVQAVVLLYFQNQA----SWTLEELSKVVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRD--NMVLIDSDDESDSGMASQADQK-EEELLLFWAYIQAMLTNLESLSLERIYSMLRMFVMTGPALAEIDLQELQGYLQKKVRDQQLIYSA-GVYRLPKNSN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX6-1", "uniprot_id": "ANC2_HUMAN", "id": "Q9UJX6-1", "name": "Anaphase-promoting complex subunit 2", "aln": "---------------MAAAVVVAEGDSDSRPGQELLVAWNTVSTGLVPPAALGLVSSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQANISPEFWNAISQCENSA-DEPQ-CLLLLLDAFGLLESRLDPYLRS-----LELLEKWTR--LGLLMGTGAQGLREEVHTMLRGVLFFSTPRTFQEMIQRLYGCFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCRQALEQFHQLSQVLHRLS--LLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVG-WLGKVFLQ----DGPARPASPEAGNT-------LRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADP----GKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSP-EREIRNVELLKLRFG-----------------------------EAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYEQLK-------------------------------------------------------------AMRTLSWKHTLGLVTMDVELADRTLS-VAVTPVQAVILLYFQDQA----SWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRD--NMVLIDSDDESDSGMASQADQK-EEELLLFWTYIQAMLTNLESLSLDRIYNMLRMFVVTGPALAEIDLQELQGYLQKKVRDQQLVYSA-GVYRLPKNCS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ISV4-1", "uniprot_id": "A0A0R4ISV4_DANRE", "id": "A0A0R4ISV4-1", "name": "Anaphase-promoting complex subunit 2", "aln": "-----------------------MNEMQSVP-QGLSVAWDTVTSSLVSPVQQNVST----------AEALSDALSLLTEHGLGQYVEGWLLETLQVRLTTSVAPEFWTGLKQPEGDS-QERD-RAKALLDAFRNLLQQLEPFLGG-----LEKLGSWQEESCGDLCGPGPHGLIERAFSVIRAILLFSPPPVLQERMLEFYSRTFSVHMS----QAGEAVEAEEGAVDTD----------EGGLCSGCATLPHLCWCQEALQQLQELSHILSRLQ--LLERVSSEAVTSILHQLIEQRMEQRYRGEYERSFLTDFNDWLGQVLG-WLSRVFSSKA--DEVGSEITPIDGKMGQPANALLQRWHCHMHQFFCRIYVNMRIEELFSIIRDFPESTPAIEDLKFCLERTNQRQQLLASLKSAFETRLLHPGVHTSDIITVYISAIKALRELDPSMVILQVACQPIRKYLRTREDTVRQIVGSLTGDSEGCTDLANELSRADPVALET-QDSEDEGSDPEDWTPDPTDALT----DKTGSKRRSSDIISLLVSIYGSKEIFVNEYKTVLADRLLHQLNYNT-AREIRNVELLKLRFG-----------------------------ESHMHYCEVMLKDVADSRRINSNIHEEERRLPAEEQPTLPLSAMIISSEFWPQLKEEKMELPAVASKAMEDYTHRFEKLK-------------------------------------------------------------AMRTLRWKPQLGSVTLDLELEDRTITDLTVSPIHAAIILHFQDKG----TWTLEELSGVLGVPQEMVRRKLALWQQQGVLREEAGGRYTVQETSTCKERSERSVMLIDSDEEGDSNTATQSEQR-EEKLQLFWAYIQAMLTNLESMTLERIHSMLRMFVAAGPGVTEMDVNELQAFLQKKVRAHQLTVST-GVYRLPKITQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1E5-1", "uniprot_id": "Q9W1E5_DROME", "id": "Q9W1E5-1", "name": "Anaphase-promoting complex subunit 2", "aln": "-------------MCDFDALWADVLRIFPVLGGANAVSNDPVEENVFQNVRQHLMVLG-------SIDTFAAVVDLEIQSTIRNVLVPKFWKHIHDGLVSSKLQGWINDQALAIEAL-PDKNGLFTQFIDAINELHDSFQSLMQV-----KPRLIQLVGAETKPTAKTVKLMQEEGIKNCLRDCLLAQLPPNFSVVVGAFYWVHFKLFTKASNLALTTVDSDVF----------------DELLCVGCNFEAEQCCCQRLTDMVNKTNMKLFEMN--LIDRLTGSALTALIKLKIKEHISDTCMGIFDRSHLKQLETWLSDVIMSWLTNIFTEWKSKDSISDIEVPESVKS----------FKVKLTYFMYETFAQSVIGQFFSIIIDYPDSIPAIDDLKICMEKIDMRVYLTESLRNSLEARILHPGVNTMDILTGYVAAIKAIRHLDSTGVILEMVTAPIKDYLRKRNDTVRRVVTGLTE--EGPTDLSEELAKG-ETIKECKDSGTDEFSNWENWQPDPFGIDASIMQYNSSRKMRSADIISMVVDIYGSKELFMTEYRNLMADRLLAQLDFNS-EKEIRNLELLKIRFG-----------------------------ESLLHSCEVMLKDVTDSKRINAHIHSDGDR---TENQLFDISSLIVSAQFWPSFNKESLQLPEEIENEFKKYTKAYEAYK-------------------------------------------------------------GNRTLNWRTVTGRVNIEIEIGDRTME-MVVSPILAVIIYHFQTKN----EWTIEDLSSITKVPASALRRRLSFWQNHGLISETTPGIFTLLEKESEKSQYEDMSLAEADEEDLESAMASASDQR-EEELQVFWSYIVGMLTNLDSMPIDRIHQMLKLFASHS-GGVEFTQDELKHFLQRKVREHKLIFSG-GVYQLAK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12440-1", "uniprot_id": "APC2_YEAST", "id": "Q12440-1", "name": "Anaphase-promoting complex subunit 2", "aln": "----------------MSFQITPTRDLKVITDELQTLSSYIFHTNIVDDLNSLLTWMS-------PNDAKSNHQLRPPSLRIKNIIKVLFPNNATTSPYSMINTSQANNSIVNEGNTNKELQLQLFSTLKEFYIFQVRYHFFLHFNNINYLKDIQRWENYYEFPLRYVPIFDVNVNDWALELNSLRHYLLNRNIKFKNNLRTRLDKLIMDDDFDLADNLIQWLKSANGSLS---------STELIVNALYSKINKFCEDNMSRVWNKRFMIMETFNKFINQYWSQFSKLVGCPEDDHELTTTVFNCFESNFLRIRTNEIFDICVLAYPDSKVT-----LLELRKIMKDFKD-----------YTNIVTTFLSDFKKYILNPSVTTVDALLRYVKTIKAFLVLDPTGRCLHSITTFVKPYFQERKHLVNVLLYAMLDLPEEELKEKINFNVDMKALLSLVDTLHDSDINQDTNITKRDKNKKSPFLWNLKVKGKRELNKDLPIRHAMLYEHILNYYIAWVPEPNDMIP----GNIKSSYIKTNLFEVLLDLFESREFFISEFRNLLTDRLFTLKFYTLDEKWTRCLKLIREKIVKFTETSHSNYITNGILGLLETTAPAADADQSNLNSIDVMLWDIKCSEELCRKMHEVAGLDPIIFPKFISLLYWKYNCDTQ-GSNDLAFHLPIDLERELQKYSDIYSQLK-------------------------------------------------------------PGRKLQLCKDKGKVEIQLAFKDGRKLVLDVSLEQCSVINQFDSPNDEPICLSLEQLSESLNIAPPRLTHLLDFWIQKGVLLKENGTYSVIEHSEMDFDQAQKTAPMEIENSNYELHNDSEIERKYELTLQRSLPFIEGMLTNLGAMKLHKIHSFLKITVPKDWGYNRITLQQLEGYLNTLADEGRLKYIANGSYEIVKNGHKNS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . .:. : : : . : : : . : : :. : : . : : * : : . . * .. *. . . : : . :::: .. . ..: . :: ..* : : : :: : : : .: : :*. : : :: :: * .* :: :* :: * .:: .:: .: : . . .: : . . . * *:* . . : . .::::.:::.:: *:::*:.*::.:::***: :. : * ::*:: :: :: :: :*** *: *..: :::. : : ..: :. :.:* :. * . :. * *.* * * ::: : * : *: . :: *: ::*:** :. : : : .* ::*:: : : . . .: .:.: : : ::: * * .:* .***** :: :.:*:.:*:: . . . .: ::*: :*: . :* * *.: * ", "identical_positions": 56, "similar_positions": 224, "identity": "5.79%" }, { "cls_id": "homologset.agr.MGI:2139150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VC66-1", "uniprot_id": "ADIP_MOUSE", "id": "Q8VC66-1", "name": "Afadin- and alpha-actinin-binding protein", "aln": "MGDWMT-VTDPVLCTENKNLSQYTSETKMSPSSLYSQQVLCSSVPLSKNVHGVFGVFCTGENIEQSISYLDQELTTFGFPSLYEESKSKEAKRELNIVAVLNCMNELLVLQRKNLLAQESVETQNLKLGSDMDHLQSCYAKLKEQLETSRREMIGLQERDRQLQCKNRSLHQLLKNEKDEVQKLQNIIASRATQYNHDVKRKEREYNKLKERLHQLVMNKKDKNIAMDVLNYVGRADGKRGSWRTDKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERAEDGTGTVAISDIEDDSGELSRDSVWGLSCDTVREQLTNSIRKQWRILKSHVEKLDNQASKVHSEGLNEEDVISRQDHEQETEKLELEIERCKEMIKAQQQLLQQQLATTCDDDTTSLLRDCYLLEEKERLKEEWTLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWVKQQFLNMTNFDHQNSENVKLFSAFSGSSDPDNLIVHSRPRQKKLHSVANGVPACTSKLTKSLPASPSTSDFRQTHSCVSEHSSISVLNITPEESKPSEVARESTDQKWSVQSRPSSREGCYSGCSSAFRSAHGDRDDLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGZ2-1", "uniprot_id": "ADIP_RAT", "id": "Q8CGZ2-1", "name": "Afadin- and alpha-actinin-binding protein", "aln": "MGDWMT-VTDPVLCTENKNLSQYTSETKMSPSSLYSQQVLCSATPLSKNVHGVFSAFCTGENIEQSISYLDQELTTFGFPSLYEESKSKEAKRELSIVALLNCMNELLVLQRKNLLAQESVETQNLKLGSDMDHLQSCYAKLKEQLEASRREMISLQERDRQLQCKNRNLHQLLKNEKEEVQKLQNIIASRATQYNHDVKRKEREYNKLKERLHQLVMNKKDKNIAMDVLNYVGRVDGKRGSWRTDKTEARNEDEMYKILLNDYEYRQKQILLENAELKKVLQQMKKEMISLLSPQKKKPRERAEDSTGTVVISDVEDDAGELSRDGVWSLSCDTVREQLTNSIRKQWRILKSHVEKLDNQASKVHSEGFHEEDVISRQDHEQETEKLELEIERCKEMIKAQQQLLQQQLATACDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWVKQQFLNMTTFDHQNSENVKLFSAFSGSSDPDNLIVHPRPRQKKPHSVANGVPACTSKLAKSLPTSP--SDFCPSRSCVSEHSPVSALTVTPEETKPNEVGRESTDQKWSVVSRPSSREGCYGGCSSAYTSSHVERDDLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2D8-1", "uniprot_id": "ADIP_HUMAN", "id": "Q9Y2D8-1", "name": "Afadin- and alpha-actinin-binding protein", "aln": "MGDWMT-VTDPGLSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTEDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTG-TVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFLNMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNGSPVCMSKLTKSLPASPSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGECTNQKWSVASRPGSQEGCYSGCSLSYTNSHVEKDDLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TUL9-1", "uniprot_id": "A0AB32TUL9_DANRE", "id": "A0AB32TUL9-1", "name": "", "aln": "MGDWWSPAMMPDPTLDTKELSS-ISGISMSPSRQNSQHSLHSTMVLPKSTYSVLSAFCTEENISQCVTYINQEVCSLGLSAVSVECKS----GSVSAVPVLNLLYEVLQLQRRAQRGLQELETQQIKNCSDLEHLQNNNCRLKDQLEHTRRENSGLHEGERQLQLKIKTLQNCLKSEKEEVQKLQSIISSRATQYNHDLKRKERDFTKLKDRLNQLLMDKRDKKLSIEVSNYVGRSDGKRGLWKTGKMEARHEGEMYKALLTDYEARQRSLMLENSELKKVLQHMKKDMIAILSPKKPCVKAELADDSLEQAGSECEDEAGESSRE-TLEQSCEQAREKLTNSIRLQWRKLKSHMERLDSQASLVASQEREAEELISRKDQEEELQRMRLELQQCKEFIHMQQQLLQQQISSPCDEETAALLNDCYTLEEKERLKEEWRLFNEQKRNFERERKNFTEAAIRLGHERKVFEEDRAAWLKTQFLNMTPFVDRKR---------PALSEPHSALSVGTEPEAKLHSTP---PLFTKSLTN--------SVFCTPKAAPVKMPTTADLYRTLNLIPESRGHGKCPSAEMLSRSRLRNSS---SDCS-VISLVRDENSSV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** : . * :.* :*. * .**** **: * *: *.*..:..:..*** :**.*.::*::**: ::*:.:: *.*. .:. *.:** : *:* ***: . :.:***::* **::***. .:**:*** :*** .*:* :**** * :.*:: **.**:******.**:*********:*****::.***:**:**:*:*:**:::::: ***** ***** *:*.* ***:*.**** **.*** **:.:::**:*******:***:**::***:* : . *.: . *: *:::** **: **: .**:****** *** ****:*:**.*.* * : . *::***:*:*:* :::.**:::***:*: ********:::. *::*::**.*** *********** **:***:******:.********* ***.***:**:*:* ****** * .:: .. *: .. : : * **.. * ..*:: * * .::. : .. * * : .. :... : ** . . ..** : :...: ", "identical_positions": 266, "similar_positions": 188, "identity": "43.18%" }, { "cls_id": "homologset.agr.MGI:2139207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9QAT4-1", "uniprot_id": "SC16A_MOUSE", "id": "E9QAT4-1", "name": "Protein transport protein Sec16A", "aln": "MQPPPQAVPSGVAGPPPAGNPRSMFWANSPYRKPANN-APVAPITRPLQPVTDPFAFNRQTLQNTPVGSSSKSSLPNLPGPALSVFSQWPGLPVTPTNAGDSSTGLHEPLSGTLSQPRADASLFPPASTPSSLPGLEVSRNAEADPSSGHEVQMLPHSAHYIPGVGPEQPLGGQMNDSGSGPDQPMNRHAPHDGAVTHAASPFLPQP--QMPGQWGPAQGGPQPSYQ-HHSPYLEGPVQNMGLQAASLPHFPPPSSLHQGPGHESHAPQTFTPASLASGEGNEIVHQQSKNHPLSSFPPKHTFEQNSRIGNMWASPELKQNPGVNKEHLLDPAHVNPFTQGNSPENQAHHPPVAATN-----HALQEAASGALSMFFQGEETENEENLSSEKAGLDKRLNLDSFSSTSRLGHPPPPGASGVYQAFPRGPSSEAAQEGDAQPYFSQSVGVRLDKQSTVPPANDAWGDVPGTGTRCASGPQCENVENLEFVQNQEVLPRETLSVDPFPLSDQIRYGPLPGPAASRPATVGLTRGGGLNLEAPDTPLHPTRPDSVSSSYSSHSHRSPPGS------ARPQELVGTFIQQEVGKLEDD-----TSGSFFKQIDSSPVGGETDEVTGSQNCCSSLSQPSTPSPPKPTGVFQTSANSSFEPVKSHLVGVKPVEADRANMVVEVRGTQYCPKKRRAAVAPPDATSGNLEQPPDNMETPCAPQACPLPLSTTGEAGQLVSNTAGTPLDTVRPVPDKRPSARAQGPVK-CESPATTLWAQNELPDFGGNVLLAPAAPALYVPVKP-KPSEVVHHPEKGMSGQKAWKQGSVPPLQNQDPPGASENLENPPKVGEEEALPVQASSGYASLLSSPPTESLHNQPVLIAQPDQSYNLAQPINFSVSLLNPNEKNQSWGDAVVGERSIVSNNWALGGDPEERAALSGVPASAVTGASLPSSIPQNCAPQGSGSSEMIASQSASWLVQQLSPQTPQSPHPNAEKGPSE------FVSSPAGNTSVMLVPPASSTLVPNSNKAKHSSNQEEAVGALDFTLNRTLENPVRMYSPSPSDGPASQQPLPNHPRQSGPGLHNQDHFYQQVTKDAQ--DQHRLERAQPELVPPRPQNSPQ-VPQASCPEPSNPESPPTQGQSESLAQP---PASPASVNTGQLL-PQPPQASSASVTSTNSSQAAVRSEQLWLHPPPPNTFGPAPQDLASYYYYRPLYDAYQSQYPSPYPSDPGTASLYYQDMYGLYEPRYRPYDSSASAYAENHRYSEPERPSSRASHYSDQLAPRQGYPEGYYNSKSGWSSHSDYYANYYSGQYD-YGDPSRWDRY-YGSRLRDPRTWDRRYWYDSEHDPYRKDHYAYSDRPEKC-----DDHWRYDPRFTGSFDDDAEIHRDPYGEEADRRSIHSEHSARSLRSTHSLPSRRSSLSSHSHQSQIYRSH-HVTGGSFEAPHAPGSFHGDYAYGTYASNFSGAHGFPEYSYPADTSWPAVEQVPSRPTSPEKFTVPHVCARFGPGGQLLKVIPNLPSEGQPALVEIHSLETLLQHTPEQEEMRSFPGPLGKDDTHKVDVINFAQN--------------KATKCLQNESLIDKESASLLWKFIILLCRQNGTVVGTDIAELLLRDHR------TVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTDS-----------------QTVTTSVLEKETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASKGLLDAAHFCYLMAQVGFG----------VYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAHTCSLPNFQVFKFIYLCRLAEMGLATQAFHYCEVIAKSVLTQPGAYSPVLISQLTQMASQLRLFDPQLKEKP-----------EEESFVEPAWLVQLQHVERQIQEGTVLWSQDGTEPQQ---------------------CRITSGSEVE---QSDGPGLNQQAGPQADNPLLMPSTEPLMHG---VQLLPTAPQTLPDGQP-------------------AHLSRVPMFPVPMSRGPLELSPAYGPPG-SALGFPESSRSDPAVLHPGQALPPTTLSLQESGLPPQEAK---------------------SPDPEMVPRGSPVRHSPPELSQEEFGESFADPGS-------------------SRTAQDLETSPVWDLGSSSLTRAP-SLTSDSEGKKPAQAVKKEPKEPKKTES--WFSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSFPRVPQVAP----TGPAGPP-----TASVNVFSRKAGGSRARYVDVLNPS---------------------------GTQRSEPALAPADFFAPLAPLPIPSN-------------------------------LFVPNPDAEEPQPADGTGCRGQAPAG--------------------------------TQSKAESTLEPKVGSSTVSAPGPELLPSKP-DGSQGG--------------------EAPGDHCPTGAPHGGSVPFYNPAQLVQASVTSGNSRPGRIGQRKYAALN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTA3-1", "uniprot_id": "A0A8I5ZTA3_RAT", "id": "A0A8I5ZTA3-1", "name": "Protein transport protein sec16", "aln": "MQPPPQAVPSGVAGPPPAGNPRSSFWANSPYRKPANNNAPVAPITRPLQPVTDPFAFNRQTLQNTPVGSSSKSSPPNLPGPALPVFSQWPGLPVPPTNAGDSSTGLHEPLPGTLSQPRADPSLFPPASTPSSLPGLEVNRSAEVDSSSGPEVQMLPHPPHYIPGVGPEQPHGGHLNDSGAGPDQSMNRHAPHDGAVAHAASPFFPQP--QMPGQWGPVHGGPPPSYH-HHSPCLEGPVQDMGPQAASLPHFPSPSSLHEGPGHESRVPQTFTPASLASGEGNEIVHQQSKNYPSSSFPPKHSFEQNSRVGNMWASAEFRQNPGVNKEHLLDPAHVNPFTQGNSPENQVHHPPVAATN-----HALQEAASGALSMFFQGEETENEENLSSEKAGLDDRLDSGSFSSTSRLGHPPLPGAGGVYQ---------AAQEGDVQPYFSQFVGIRHDKQTTMTPANDAWGDIPGAGTHCASGPQCENVENLEFVQNQEVLPRETVNVDPFSPSDQFRYGPLPGPAASRPVTSGLTRGGGLNLEAPDMPLHPTRPDSVSSSYSNHSHRSPPGS------ARPQELVGTFIQQEVGKLEDD-----TSGSFFKQIDSSPVGGETDEMTRSQNYCSSLSQPSTPSPPKPTGVFQTSANSSFEPVKSHLVGVKPVEADRANMVVEVRGTQNCQKHG-AAVLPPDATPGNLEQPPDNMETLCAPQACPLPLSTTGEAGQLVSHTAGPPLDTVRPMPDKRSSARAQGPVK-CESPATTLWAQNELPDFGGNVLLAPAAPALYVPVKP-KPSEVVHHPEKGMSGQQSWKSGSVPPLQNQDPPGASENLENPPKVGEEEALPLQASSGYASLLSSPPTESLHNQPVLIAQPDQSYNLAQPINFSVSLPNPNEKNQCWGDAVVGEKSMVS-TRALGADHEEHAALSAIPASTVTGSSLPNSVTQNCAPRGSGSSEMIASQPASWLVQQLSPQIPQSQHPNAEKGPSE------FVNSPA-NGSVMLAPPANSAVIPNSNKGYHSRNPEEAIGALDFTLSRTLENPVRMCSPSHSNSPASQQPLANHPRQSGPGLHNQDHFYQQVTKDAQ--DHRSLERGQSELVPPPPQNSPQQVPQAACPEPSNPESPPTQGQSEGLVQP---SASPAPVNTGQQ--PQPPQSSSASVTSTNSNQAAVRSEQPWLHPPP-TTFGPAPQDLASYYYYRPPYEAYQSPYPSPYPSDPGAASLYYQDIYGLYEPRYRPYDSSASAYAENHRYSEPERPSSRASHYSDQLTPRQGYPEGYYNSKSGWSSHSDYYANYYSGQYD-YGDPGRWDRY-YGSRFRDPRTWDRRYWYDSDHDPYRKDNYAYSDRPEKC-----DDHWRYDPRFTGSFDDDTELHRDPYGEEVDRRSIHSEHSARSLRSTHSLPSRRSSLSSHSHQSQIYRSH-HVTGGSFEAPHAPGSFHGDYAYGTYASNFSGAHGFPEYSYPADTSWPAAEQVPSRPTSPEKFTVPHVCARFGPGGQLLKVIPNLPSEGQPALVEIHSLETLLQHTPEQEEMRSFPGPLGKDDTHKVDVINFAQN--------------KATKCLQNESLIDKESASLLWNFIILLCRQNGTVVGTDIAELLLRDHR------TVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTDS-----------------QTVTSSVLEKETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASKGLLDAAHFCYLMAQVGFG----------VYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAHTCSLPNFQVFKFIYLCRLAEMGLATQAFHYCEVIAKSVLTQPTAYSPVLISQLIQMASQLRLFDPQLKEKP-----------EEESFVEPAWLVQLQHVERQIQEGTVLWNQDGTEPQQ---------------------CHITSGSEVE---QPDGPGLNQQAGPRADNPLLMPSTEPLVHS---VQLLPTAPQTLPDGQP-------------------AHLARVPMFPVPMSRPPLELSAAYGPPG-SVLGFPESSRSDPAVLHPGQALPPATPGLQESGPPLQEAR---------------------SPDPEMVPQGSPVRHSPPEPREEEFGKNVADLGS-------------------SRTAQDSETSPVWDLGSSSLTRAP-SLTPDSEGKKPAQAVKKEPKEPKKTES--WFSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSFPRVPQAAP----TGPAGPP-----MASVNVFSRKAGGSRARYVDVLNPS---------------------------GTQRSEPALAPADFFAPLAPLPIPSN-------------------------------LFVPNPDAEESQPADGTGCRGQAPAG--------------------------------TQSKAEPTLEAKVVSSTVSAPGPELSPSKPADGSQGGELSRCSSLSSLSQEVSRHFHQAPGDHCPAGATPGGSVPFYNPAQLVQASVTSGTSRPGRIGQRKYAALN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15027-1", "uniprot_id": "SC16A_HUMAN", "id": "O15027-1", "name": "Protein transport protein Sec16A", "aln": "MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQ-HRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAP-----------------THVGAGSLCQALLPGPSNE------AAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTG-------APDATLHTVHPDSVSSSYSSRSHGRLSGS------ARPQELVGTFIQQEVGKPEDE-----ASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVK-CESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKP-QPP-VVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVS-SWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQ--GQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQS---PASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYYSSQYD-YGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKR-----DNNWRYDPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIYRSH-NVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPTSPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGPLAKDDTHKVDVINFAQN--------------KAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELLLRDHR------TVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGG-----------------PAAAASSLERETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAHFCYLMAQAGFG----------VYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLPSFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDPQLKEKP-----------EEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQ---------------------CPGTPSSEME---QLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPL-------------------ASPARVPMFPVPLPPGPLEPGPGCVTPG-PALGFLEPS---------GPGLPPGVPPLQERRHLLQEAR---------------------SPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP-------------------SRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGES--WFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAP----PALPGPP-----GAPVNMYSRRAAGTRARYVDVLNPS---------------------------GTQRSEPALAPADFVAPLAPLPIPSN-------------------------------LFVPTPDAEEPQLPDGTGREGPAAAR--------------------------------GLANPEPAPEPKVLSSAASLPGSELPSSRP-EGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATSGSSRLGRIGQRKHLVLN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B225-1", "uniprot_id": "A0A8M3B225_DANRE", "id": "A0A8M3B225-1", "name": "Protein transport protein sec16", "aln": "MQPPPRTTPPGASGPPPPSGGPNSFRRNRPHKHGAAS--AMTPAAPSTMPVTDPFAFGRQNFSSMAGSSQ---APPTNSNPLPMQSPPLPGFNPTAPPQGPP------PGPAQAASPGPPPRIFTPQPVPSRPGSSSIPPPAEAGYFSSQ--EPIPYIAQLPNPAPPLIPSTSHPPSTTPTPP-------------VQSQAPFHSQPTPPLPSHWVPEHGSRPPSVQNYFQPTSDLPSQPFQAQAP----HPGPSPLTAPPPVPSPLTAPPPLTSPLTAPPLTQSQNQFQSAQPNVSGPAATYQQNS----HFPAHNYFSQSGGPSEPWFN-------QNPQDPSQRAYHVPYSEVP----------SDSGTLSMFFGGNDVENEETLTGE--GRVNGIHQPLHSTTEFSG-----------------------------------------------------PYLNDSGNIRAGTGPSDSVENLECVPNQEVLPSEPP------PSHAFEGGPN--------------------LETPDSAPRLARSASVSSSYSNVSHSSGHGAHSGGHVPRRQQVVGTFIQQESPRPPDHPPLHPSTGGYFEQIDSNPAAEASPTFP-------------TPSPPKPVGVFQASANSSFEPVRSHGVGVRPAEVDRARVVMEKGG--------------RDMQPGNLEHPPDNLETIYLS--------------------------------ERRPSSRAQGARRPIESPATALWAQNDTASLSANILLAPAAPSLTATFVPAHPSEVIQPPEDGPLDLHPARPDPQPP---------SENLEIPPDS------TPQASLGYASLLVTSPPEEALNQPVLIAPPSSNYSLIS----SQNLLQPS---------------------ILPSPQETAAPVHPHPQSSLTNQMPQNSPPTNQPPLLFSQTPVNFSSSSAQGVLNLTREANDGQAARPN-----------LSRAQSLKGDSQFLPPS-ATQAPPSSAASTNHNQPSNYQLLDFSMHQ----------PQSTNQVTSVPAVSQSTHPAG-LVNNTPGFYLQVTKDAQQGGQSDTDSLSHQQNSNPPLPSSNQLDNNQTLN-SHPPPPPAQNQPPPQAPPTH-PGAPPTGPGSAQPPPYPPQSGNSTTQPPQEPQRPPSSLGSQSGYGVPPAMPPGPGYPGYYPGAYPEYQDGRVPYPPQYPVDPRTQNYYQDDPYRRGDPRYGWYDGQNPGYREAER--QPERPSSRTSQYSDRPSSRQGYQEDFS--RSSRSAYDEYYANYYKRQYDAYGDRSRWYDPNAAYDPRYKAYYDQMYGWYYNQDGYRGGQAYYNQQYQNRGREGYDDPWRYYPGYDSSFDDDSR-RRDPYADDFDRRSVHSEQSAHSVHSSH---SRRSSFSSRSQQSQVYRSQPDLVSAAYDATG--TTLPADYTYSQYPNPSDTVNYGQDPYNSADNTWSAPEQPPPRPLTPEKFSIPHRCARFGPAGQLILVQPNLPSAGQPTLVEIHSMETLLQDSPEQSDMRSFPGPLVKEETHKVDVMKFAQN--------------KAQECLRNDDLIDKDSAYLIWEFIVLLCRQNGTVVGTDIADLLLKEHR------SVWLPGKSPNEANLIDFNNEAIEHAEEDMG---QMSLLSDT-----------------FMGVPENIGKDTERFRELLLFGRKKDALESAMKNGLWGHALLLASKMDNRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAAATCCGDEKWGDWRPHLAMVLSNLTHTLDLDTRTISTMGDTLASKGLVDAAHFCYLMAQVGFG----------VYTKKSTKMVLISSNHSLPFLKFCSSEAIQRTESYEYAQSLGSQPLSLPNFQVFKFIYACRLAESGLCAQAFHYCEVISRTLLSLPEYYSPVFISQLIQMSLRLRFFDPQLKERP-----------EQELFIEPDWLLHLRQLDGQIKEGVISLRTDRSTPQL---------------------YPCSTPSSED---QCSPPEP-PALTPDPHNALMTSLVPP-----AAVQLMPPAPPTILQDGA-------------------VSLQQVPPPSESVPFYPVAPGPPQPNFV-APYQPEMQEQYMPMPPQIPQHMPPQMPTYNPAEMPPQMPQGMPGQMPPP---MHGAERGSAPSSPQQFPQPSPTFANPPPPGKD-FYDEMARLGPGRRSRTTSQSSMHMAPGRRSRTTSESSNHSGRERSSSFANQGSPPPPPIPEAPPQDVPERTKKDSPKKQGSGGGLLTWLFPKRKNEAHLPDDKNKSIVWDEKKQKWVNLDEPEEESKPPPPPPTGFPKAPMSAPAMVPPGVAGPPS----GPPVNMFSRRAG-TRSRYVDVLNPGRG-------------------------GAKAVASVPPPADLFAPLAPMAMPAN-------------------------------LFTPAAAPDEQQPMEGS--VPDTSGE--------------------------------NTLQTSATVPQMFNPNAALPPGPE--------GTQSGELSRSSSMSSLSREVSQHLNQAPAQQPVQGAPPAGGVTFYNPSQFAQSVPTN-RTRPGRLGQRGYPTPK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEM2-1", "uniprot_id": "X2JEM2_DROME", "id": "X2JEM2-1", "name": "", "aln": "------MLHNNAPWLPPHQQQQQQAPQQHPTPQQQHAMPQQQQTLPAQQQQQQ--VYASQMFQQHQPNYWPEDQHQQQQQPQSLNYNNYFPGQQQQHPMQQQQLPPQQQLPPQQQQPTQQQHTIQQQLYYPTQQQPQVPAPAEP----------------ALDSFDNNNSGGGGGGGRSDG------------------------------WGDWGDWNDNSNNNNSNGTDGLLEPTGQLLEDSFNVQSSQGSWQAFATSNNVNNNGELPPPANPQSTSLQQQPLNQQSIPLLHQQPQSPPELGQEPELDAIVPPQAFQNQP--------------PTAAPPPTSLTSFSAQMTAVG---------------SPIYAVGASSAHSAGVGASPAPPTGVVAPPAHLAG-----------------------------------------------------------IGAPPAHLAGVGASPAPSALVGASPAPIIGVGAP------PVGAPPVGAPP-------------------ADATTIAPPAALPPSIVPSSGSNPFKRSTGLN---------KRVNIMADPAAGAPSPP----------------APAAAIAPVAP------------VAPIPPPADQLFGMPAEAHGEGFN--LIAAPPVEASLGTPLS-------------------APIPAPIPVPNASLYASPAVP--------------------------------QAFAHLEPDNQEVLSAPNDERAQYLQTSHLSEQLGEGEADQDAGLLPPPGLSRLVLGQPELDSQQQRQVTGATEQP---------PLNVAQAAALHMQE----RRADGEDTSDGEQQVRNIQTPPRRVVTGVETNAPSLREQREVVLDGEN---------------------LEDREAIPPPTLAELPTTSVHHNILPDEAEQLHHNNPPQAMTPLNAQQPHQQQSTLQQQHQQHSTTQQEKKR---------AAVGRRTTASLDLESDESDEFLQSERERDRERERRDLMEERHSRGRSHSHYPYEGETEDSVRGAAHHETKSLRETHHKRNHDSARSRRHQDPKVERERERDRERDRTWRRRSNKYHSGGEDPDRSYDHSRRYNNSNYEGESDNPEYN-H-MGDAELDGSGGRSSKTSRHRRSAAEEDFDDYERERNRSRRSTKPQSSAEKSRSSGGRRNYENSGRSARADDGRRRYQDQRNPGAQYPVSATGYVPYG-MYEQMSRNPQVYADMYAKFYGQMINSMNAAVS-AAASKGGVPAGAGVIPGLMPSAVPVSAAQLVAATS----GGSVSGSSEAAMLRERERYTHAYITQANEFHRHQYKELIYQQQQQQ---------------------QQQQQQQQQREDHLNSSFSVAEDNASFYGSHGGGSIYNQYQSYPLSSARSLSN--LNGDGRNSRCGPYYAGSECGLDIRAAADAAPSTYGGVAGTAGPVTNTAVARPPRRRTPLQFSRPHLVASYAMS-LLLKVKPKYAGRGR--LRNDVEVAPPRIRDGTSSLLRMYPGPLQGRKLHKDKIISFCKEQIRLGPTKGCTALYATQKKPQGSVTKYRASHALMWHLLILLLRQNGYIADTDVGDLLLENQQEYPYDPSEFEAENEPDADAEQDAAAPADKTVDSDLDSESAAGVTPAEPLAAGAATSSINGADAANAATPLSEQAATDKFRSYVLRGNVEEALQWATDNGLWTHAFFLALYEDRYALTDVAQKFLNRAIKANDPLQTLYQMKSCHTPACVSQLRDEQWGDWRSHLSILVTNKSRQPEYDRSSVVALGDTLFQRGDIYAAHFCYLVAQEEFGRYDSSATELTTLTANVPRLILLGSSHYKHFNEFASNEAIIMTEIYEYARSLFDPKFSIAHFQHYKFLLATRILDYGQHFRCTNYLEQIARHIELKPESYDSNFIQRVCGLAERLRYHDPILINRVSFASPPNATSKDSAAAEEKAWLRQLRSLAYVQPQQEQLQQLQQNQQVQQEQNDIDQQFAEVNKQFRELNMQYESNSNMENTLQPQLPPVDQQPPQQQQQVLSESYQQPTQQYYEPPPQAPTESDPYGQGQPSYYDPNAGQLHYDPNAAQHQYDQQQPQPQPTPSYGQIEPGTEAYQPGQATADPAAVPSGYGYDYWSGTQQPPYGDEPNENQAALKDEEEEDEEQDEQQILQYAKQQILQQTKQQQLQQEQHTRSNGAASINNRFKSNALKQERSSGSLRKRQE--------ASRTATIAAAAAAIAQITPATVAAAATPPAASAKAFNLNDVSSFSSTNKRHQATSSSNNRSSSNQAAAAAAATKAAAIATVPAAPNQLLSCRKSNSQNSPYLATPKTLTTPTRFIAAKAATVTATPTAPATSTTTSTTIGARGSSTKRVYFNLPSTIAESEQEFEHELDYDEEMEEENSMALAQAKPNVHLARKPHIVFNGTYPIDMPLTQGQSQLKSNSYDPEANADRGDLQRYRNYMLHDYVIDEDAEGEEQAEEEGEEDEYGDGDEDLFPYADDDESFDDGDYYTHQLLNKYGIIPSGEKQRVERTPASVEAATSAAQPQHVWSMKELIANPAIPLNYKKMCSEVEQSLSRFENYLDSKKEQQVPPGAAVRTFDIDAPTRRGHRSSTSTNAGLDLRSKKKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48415-1", "uniprot_id": "SEC16_YEAST", "id": "P48415-1", "name": "COPII coat assembly protein SEC16", "aln": "--MTPEAKKRKNQKKKLKQKQKKAAEKAASHSEEPLELPESTINSSFNDDSVNRTESDIASKSDVPPVSSSTNISPANETQLEIPDTQELHHKLLNDSDQHDITADSNDLPDNSIVEHDSVITQTKPAMSQEYEETAAHLSSRNPSLDVVAGELHNNNEHTQKIAVSAVEEDSFNEEEGENHDS-------------------------IIISSLNDATPSQYNHFLPSDGNLLSPELSSGDTPTHNVPLGTKDNEINDDEYCNDKEISLNANNVLPDELSKEEDERLKLETHVSTEEKKQDIADQETAENLFTSSTEPSEN--------------KIRNSGDDTSMLFQDDESDQK---------VPWEEDVKKDFHNENTNNTQESAPNTDDRDKGYEGNEALKKS----------------------------------------------------------ESCTAADERSYSEETSEDIFHGHDKQVVEGQNDFTGKNIENESQKLMGEGN------------------HKLPLSAEADIIEPGKDIQDQAEDLFTQSSGDLG-----EVLPWESTDKNADVTSKSQE-----------KHEDLFAASGNDEKLPWEVS-------DGEVSSGKTENSMQTSTEKIAEQKFSFLENDDDLLDDDDSFLAS------------------SEEEDTVPNTDNTTNLTSKPVE------------------------------EKKASRYKPIIEEEAGMRQEQVHFTNTTGIVTPQQFHGLTKTGLGTPNQQVSVPNIVSPKPPVVKDNRSNFKINEEKKK-------SDAYDFPLEIISESSKKGHAKPVAVPTQRFGSGNSFSSLDKPIPQSRKGSNNSNRPPVIPLGTQEP------------------------RSSRTNSAISQSPVNYAFPNPYKIQQLQQAPIQSGMPLPNTNIPPPALKVETTVSAPPIRARGVSNASVGS-------SASFGARHATQYGLNNGVPPVSPYGQATINLPTANKYAPVSPTVQQ------KQYPSVVQNLGASAVNTPNFVKTHRGHTSSISSYTPNQNEHASRYAPNYQQSYQVPYTSQPVGPVAGNSSYQSQTRSSYAVPMMPQAQTSASIQPHANIQPPTGILPLAPLRPLDPLQAATNLQPRASNITAANSLPLANLPLAENILPEIITHRATSSVAPPRQENNPIKIDNEALLRRQFPIFHWSAANKVVYAVPPIPDQSQYMISSSIVQEIKVTPIDQIIKPNDMLKSFPGPLGSAKLKKKDLTKWMETTIKSISENES-STDMTIWQLLEMKLNDKVNWKNISKLLYNSDELLMYLSQPFPNGDMIPN---------AYRLDINCQMRVLAFLQTGNHDEALRLALSKRDYAIALLVGSLMGKDRWSEVIQKYLYEGFTAGPNDQKELAHFLLLIFQVFVGNSKMAIKSFYTNNETSQWASENWKSIVAAVLINIPENNEDP-LLIPPVVLEFLIEFGIFLTKKGLTAAASTLFIIGNVPLSNEPVMADSDVIFESIGNMNTFESILWDEIYEYIFS-------------------YDPKFKGFSSILPQKIYHASLLQEQGLNSLGTKYTDYLSSSVR--------KLPKKDILTINLTRELSEVASRLSESNTGWLAKPKLSSVWG---------------QLDKSFNKYIGGDDIDALNKKNDKKKVFDGFTPG--------SSANSSTVDLTQTFTPFQA-QVTSQSYVDTTALLHNAHNVPSHSVLHSKPSNVSKGLVEANLPYTHRIGDSLQGSPQRIHNTQFAAAEPQMASLRRVRTDQHTN------------EKALKSQQILEKKSTAYTPQFGQNHSVPMEKSNSNVPSLFADFPAPPKLGTVPSNYVSSPDLVRRESIISTGSEFLPPPKIGVPTKANSSQGSLMYSPSVEALPIDPVVPQVHETGYNDFGNKHSQKSMPEDESHTSHDNSNADQNTLKDSADVTDETMDIE-------------------GPGFNDVKNLLPMEPNHQPTSTVNPIQTISDDIQPILQTNVEVRGTDASKMENSLPSIENERS-------------------SEEQPENISKSASSAYLPSTGGLSLENRPLTQDENSISETVQSTYLPAGSISMEAKPISQVQDVPRNVNN--------------------KASKLVEQHMAPPKPKSTDATKMNYSPYVPQSTAASAD--------------GDESTILKTSPAIYARTHQAHASNPSQYFPLVNQANETASFELSESTSQAQSNGNVASENRFSPIKKAEVVEKDTFQPTIRKASTNQYRAFKPLESDADKYNDVIEDESDDDNMSTDEAKNRKEEKKNVN-MKKETKPSNKDIDDKSNGWFGWLKKDTG-------------------------DKKVYKAKLGHKNTLYYDEKLKRWVN---------------------------------KDATEEEKQKIIESSAPPPPPIVKR-------------------------------KDGGPKTKPRSGPINNSLPPVHATSVIPNNPITGEPLPIKTSPSPTGPNPNNSPSPSSPISRISGVNLTSKKANGLDDLLSLAGGPKPASTRRKKKTARGYVNVMDNIQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .. . :. . . . . . : . . . . :: .. .: . : . . : . . . . : : * . . . . .. . * . : ... . . . : .:: * . : : . . : : . . : . : :: : . . : . .. . : ..: * . . . : : : . :: . . . : ... : . : :. . . . . . . * . . . : : : : : . .: . .. . . . . .: . . . . * : * :: .. . : : . :. . . .: .: . . ** .*. .*. : * . : . :. . . ... . . : : . :..:: . : . : . * : :. ::* : . : .. : .: . : : :. . : : : :* . * : : :: . :: .. :* ..:: : . . ** . . : * :. * .. . : : . ** : : .. .. * : : . : . . . . . : . .. : . . : : ..:. . . . . : . :: :.: . . . . . . :.. . . : . : : : : . : . . . : . ", "identical_positions": 24, "similar_positions": 296, "identity": "0.9%" }, { "cls_id": "homologset.agr.MGI:2139220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLL4-1", "uniprot_id": "TM9S4_RAT", "id": "Q4KLL4-1", "name": "Transmembrane 9 superfamily member 4", "aln": "------MAAAMIWWPRFLLLLCLTCKGSTFYVPGVAPINFHQNDPVEIKAVKLTSSR------------------TQLPYEYYS--LPFCQPNK--ITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCGQSNKPVILTVEQSRLVAERITEEYYVHLIADNLPVATRLELYSSNRDSDDK------------------------KKEK----DVQFEHGYRLG-----FTDVNKIYLHNHLSFILYYHREDTEEDQEHTYRVVRFEVIPQSIRLEDLKIDEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDN-PVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSG-GSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH24-1", "uniprot_id": "TM9S4_MOUSE", "id": "Q8BH24-1", "name": "Transmembrane 9 superfamily member 4", "aln": "------MAAAMIWWPRFLLLLCLTCKGSTFYVPGVAPINFHQNDPVEIKAVKLTSSR------------------TQLPYEYYS--LPFCQPIK--ITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCNQSNKPITLTVEQSRLVAERITEEYYVHLIADNLPVATRLELYSSNRDSDDK------------------------KKEK----DVQFEHGYRLG-----FTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTGEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDN-PVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSG-GSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92544-1", "uniprot_id": "TM9S4_HUMAN", "id": "Q92544-1", "name": "Transmembrane 9 superfamily member 4", "aln": "------MATAMDWLPWSLLLFSLMCETSAFYVPGVAPINFHQNDPVEIKAVKLTSSR------------------TQLPYEYYS--LPFCQPSK--ITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSNKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYS-NRDSDDK------------------------KKEK----DVQFEHGYRLG-----FTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKADEKSSCTLPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDN-PVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSG-GSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4U1-1", "uniprot_id": "F1Q4U1_DANRE", "id": "F1Q4U1-1", "name": "Transmembrane 9 superfamily member", "aln": "MTRVFKMAAAMEMWA-LLLVSTLPCVAP-FYVPGVAPMNFHQNSPVEIKAVKLTSSR------------------TQLPYEYYS--LPFCKPEN--IVYKAENLGEVLRGDRIVNTLYTVFMNLDKKCEVLCKKPESPIKLSVEESKLLAERIQEEYYIHLIADNLPVATRLELYPNKEEAIDE------------------------EQKKDTLKDVQFEHGYRLG-----FTENNKFYLHNHLSFILYFHKEKLEDAEEHNYRVVRFEVMPKSVKLEDIKADDRGTCTLPETVAPVPQEIDPSKENNILFTYSVHWQESEVKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNREDDIEDTMEESGWKNVHGDVFRPPQYPMILSSLLGSGIQMFSMVLIVIFVAMLGMLSPSSRGALMTTACFLFMFMGLFGGYFAGRLYRTLKGHRWKKGAFCTATLYPAVVFGICFVLNCFIWGEHSSGAVPFTTMLALLCMWFGISLPLVYLGYYFGFRKQPYDN-PVRTNQIPRQVPEQRWYMNKFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRTFLVSG-GSAFYVLIYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYVFIRKIYAAVKID", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3N6-1", "uniprot_id": "Q9V3N6_DROME", "id": "Q9V3N6-1", "name": "Transmembrane 9 superfamily member", "aln": "----MQSGALARPCLAIVLLAGVVLVADSFYVPGVAPVEFVQDQKIDVKAVKMTSSR------------------TQLPYQYYS--LRFCYPKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHEYFVHLLVDNLPVATRIVSVNNPA-------------------------------------EVTYEHGYRLG-----QVDGDNIYINNHLKFILSYHMHSKDK-----YRVVGFEVETVSVSHKELKFHG-DTCNFPDSAR--PQLVNPNGETQLYFTYSVEWKESKVSWASRWDIYLGMRDVQIHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNIEDTLEETGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLGFYLGYRKQPYQH-PVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSG-GSAVYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04562-1", "uniprot_id": "TMN2_YEAST", "id": "Q04562-1", "name": "Transmembrane 9 superfamily member 2", "aln": "-----------MKRGVWLLIYCYATLTKGFSLPGLSPTTYHSGDEIPLLVNRLTPSIYFQHQDEEGNDVSGDKEHFLYSYDYYNKRFHFCRPEH--VEKQPESLGSVIFGDRIYNSPFQLNMLEEKECVALCKS-----TIPGKDAKFINTLIKSGFFQNWLVDGLPAARKAYDSRTKTNYYGTGFELGFTDVKQTVDGKAVPSTMEELTSEASNEDVILDARLPKNVKPNLVKTVELPYFVNHFDIEVEFHDRGNDN-----YRVVGVIVNPVSIERSSP-----GACST----TGKPLILDEDKDNEVYFTYSVKFVASDTVWATRWDKYLHIYDPQIQWFSLINFSVIVILLSSVVMHSLLRALKSDLARYNELNLDNEFHEDSGWKLGHGDVFRTPSKSMLLSILVGSGMQLFLMVMCSIFFAAVGLVSPVSRGSLPTVMFVLYALFGFVGSYASMGVYKFFRGPYWKANMILTPILLPGAIFLLIVIMNFFLLFAHSSGVIPARSLFFIILLWFLVSVPLSFAGSIVAHKQCNWDEHPTKTNQIARQIPYQPWYLRTAQATLIAGIFSFGSIAVELYFIYSSLWFNKIFYMFGFLLFSFLLLTLTTSLVTILITYYSLCLENWLWQWRSFIIGGLGCSIYTFIHSIL--FTKFKLGGVITVVLYLGYSLIISALCCVVTGAIGFFSSMFFIRKIYSAIKVE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32802-1", "uniprot_id": "TMN1_YEAST", "id": "P32802-1", "name": "Transmembrane 9 superfamily member 1", "aln": "-------MIYKMAHVQLLLLYFFVSTVKAFYLPGVAPTTYRENDNIPLLVNHLTPSMNYQHKDEDGNNVSGDKENFLYSYDYYYNRFHFCQPEK--VEKQPESLGSVIFGDRIYNSPFQLNMLQEKECESLCKT-----VIPGDDAKFINKLIKNGFFQNWLIDGLPAAREVYDGRTKTSFYGAGFNLGFVQVTQGTDIEATP-----KGAETTDKDVELETRNDR----NMVKTYELPYFANHFDIMIEYHDRGEGN-----YRVVGVIVEPVSIKRSSP-----GTCET----TGSPLMLDEGNDNEVYFTYSVKFNESATSWATRWDKYLHVYDPSIQWFSLINFSLVVVLLSSVVIHSLLRALKSDFARYNELNLDDDFQEDSGWKLNHGDVFRSPSQSLTLSILVGSGVQLFLMVTCSIFFAALGFLSPSSRGSLATVMFILYALFGFVGSYTSMGIYKFFNGPYWKANLILTPLLVPGAILLIIIALNFFLMFVHSSGVIPASTLFFMVFLWFLFSIPLSFAGSLIARKRCHWDEHPTKTNQIARQIPFQPWYLKTIPATLIAGIFPFGSIAVELYFIYTSLWFNKIFYMFGFLFFSFLLLTLTSSLVTILITYHSLCLENWKWQWRGFIIGGAGCALYVFIHSIL--FTKFKLGGFTTIVLYVGYSSVISLLCCLVTGSIGFISSMLFVRKIYSSIKVD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: * :**::* : ... : : . ::*.* .*:** : ** * : : :.*.**.*: **** *: : : * : :* ** . .:: :: * :: : : *.**.* . :* : : *: **:.: : :* . . **** . * . *: .. .:* * :: :.:: *****.: * **:*** ** : * .*:***:** ::*.:**.:: ::*:*: *:*.** : :: *::*** ******.*. . :* ::***:*:* * **.* :*::** ***:* * .:: ::* ...: : :*: :.* ** : *. * *. :: . :* *: ***.:* ::. :: :** .*:** : * .. :: ::. *.:** *.**:* * **:. . *:***:.**:: :**:*:::::* *:::*:****:: * :*.:: : ::*::.*..** *:: * ** *::.* *.:.*.:.::*: ..*:.: . . :**.**: :: ::**:*** :: .*: :**.::*::", "identical_positions": 177, "similar_positions": 221, "identity": "25.07%" }, { "cls_id": "homologset.agr.MGI:2139258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QR86-1", "uniprot_id": "DEPD7_RAT", "id": "Q4QR86-1", "name": "DEP domain-containing protein 7", "aln": "MATVREKAAALDLS-ALHSPAQRPPGFSVAQKPFGATY-------VWSSIINTLQTQVEVKKRRHHLKRHNDCFVGSEAVDVIYSHLTQNKFFGDVDIPRAKVVRVCQALMDYKVFEAVQTRVFGKDKK-PAFEDSSCSLYRFTTIPNQ--DSQ----LGH----ENKGTSP--SRFSDALFKS-SDIKSD-SLEDLWENLSLKPTNSP--HVSTRLSPQVINEVWQEETIGRLLQLVDLPFLDSLLKQQE-VVPKAPQSKRQPDMVNTSNYLDRGILRAYGDSQEDEWISAAIDCLEYLPDQMVVDISRNFP----EQPDRTD------LVKELLFGAIGKYY--STREPLLN-HLSDVHNGIAELLVNGKTEIALEATQLFLKLLDSQNREEFRRLLYFMAVAADPSEFKLQEESDNRMVVKRVFSKAIVNNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLLAIQKGRDPNKDTGYIYCQRIDGREYSSSIQKKTKDQLLSLLKTIDEDSKLSAKEKKKLLGQFHKSHPDIFIEYFGDSF--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WS7-1", "uniprot_id": "DEPD7_MOUSE", "id": "Q91WS7-1", "name": "DEP domain-containing protein 7", "aln": "MATVREKAAALNLS-ALHSPAQRPPGFSVAQKPFGATY-------VWSSIINTLQTQVEVKKRRHHLKRHNDCFVGSEAVDVIYSHLTQNKFFGDVDIPRAKVVRVCQALMDYKVFEAVQTRVFGKDKK-PTFEDSSCSLYRFTTIPNQ--DNQ----LGH----ENKVHSP--SRYSDASFMS-SDIKSD-SLEDLWENLSLKPASSPHIHISTRLSPQVINEVWQEETIGRLLQLVDLPFLDSLLKQQE-VVPKAPQSKRQPDMVNTSNYLDRGILRAYGDSQEDEWISAAIDCLEYLPDQMVVDISRNFP----EQPDRTD------LVKELLFDAIGRYY--STREPLLN-HLYDVHNGIAELLVNGKTEMALEATQLFLKLQDSQNREEFRRLLYFMAVAADPSEFKLQEESDNRMVVKRVFSKAIVNNKNVSKGKTDLLVLFLMDHQKDVFKIPAALHKIVSVKLLAIQKGRDPNKDTGYIYCQRIDESEYSSSTKKKTKDQLLSLLKTIDEDSKLSAKEKKKLLGQFRKTHPDIFTEYFGD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QD5-1", "uniprot_id": "DEPD7_HUMAN", "id": "Q96QD5-1", "name": "DEP domain-containing protein 7", "aln": "MATVQEKAAALNLS-ALHSPAHRPPGFSVAQKPFGATY-------VWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKK-PTFEDSSCSLYRFTTIPNQ--DSQ----LGK----ENKLYSP--ARYADALFKS-SDIRSA-SLEDLWENLSLKPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQE-AVPKIPQPKRQSTMVNSSNYLDRGILKAYSDSQEDEWLSAAIDCLEYLPDQMVVEISRSFP----EQPDRTD------LVKELLFDAIGRYY--SSREPLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKEKKKLLGQFYKCHPDIFIEHFGD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JQ19-1", "uniprot_id": "DEPD7_DANRE", "id": "Q1JQ19-1", "name": "DEP domain-containing protein 7", "aln": "--------------------MHTPPDTGMAGKPFRATY-------IWTNIINNLQTQVEVKRRRHNLKIYPDCFLGSEAVDVVLAHIIQSKVCGDAEVPRFKAVRLCQALMEARVFEAVDTKVFGKEKRQAKFEDSSCSLYRFLNRQTP--STSGSETIGSGYNTQRNTNSPPFQRMEDSAYSNNSPVKTDKSLEDVLGNLNMNTTITP-QMMNLGLSQELMDEIWRQQTVLRLLQLIELPLLESLLEGQESPRPPLHSMDSDPDLLYTSSYLDREILKAFSEAQADSWLSAAVDCQEFLPDQLVVDVSRGLA----KCEEETS------QYKQLLYGVLVQHYGQSDYPPLLTNHVFDIHSGVSELLVNGKCEQALESLQLCLKLQDSRSREELRRLLRFMALAGSPHQIKLHKEIENRMAVKRAFSNAIVYGTKLAKGKVDLLVLFMMDKHHDLFKIPVTLHKLVSDKLASIIKGTDPDRITGTTYCRHLSGKEFVETVQKTTREELWTLLKTIHENTKLSLKEKRRLLGQFYKGHPEIFVQYFGNRISNIYI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TD67-1", "uniprot_id": "A0A8N7TD67_DANRE", "id": "A0A8N7TD67-1", "name": "DEP domain-containing protein 7", "aln": "MASVQEKVAVLNKVGKLYTPLNPPLDHRLINRPHDVQTNTVQNKDMWRQMVAALRSRVTVKKRRQNLKTHENCFLGCEAVDVLQDYLTQNKVFRDVLVSRALAVRLCQVLMDCRVFEAM-----GKASIEGVFQDSSR-FYRFLNTEDPSLDSLDAVIFASG---EESLMNVTPCRQDVLLFSHSTPVKPDQALDRLMEKLDLTGLVGS--SPDKCLPPSVVREVWQEQTVRRLSQLIDLPLLEGVLNCSKIVSPPSRGSNNEPDLLYTSSYLDREVLKAFRESQDDDWLSAAIDLLDFLPDHLVVEVSRELPSFSCEDDDDCDEGQSMCECKLLLFHVLEKHYGHMERKPLLSDSMADVYTEIMELLVNGRFERALEVLQLTLKLLSASAREELRRLLEFMAVAADAGNVRLHKETENRMFVKKSFTRAVIQSKSWTKGNVDLLVLFMLDNHQEIFKIPGSLHKLVSEKLDDIVKRRDS--ATEIPFCQQVPRDVYTETIKDSTKNELYLLLKNIDENTKYSLKEKKRLLGQFYKGHPDIFMQYFGSRLSTLNLLEA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : :*. . :* .:: *:::* **:**:.** : :**:*.*****: :: *.* *. :.* .**:**.**: :****: ** . *:*** :*** . .. :. :.. . * : : ::. :*: : :*.:. . . *. .:: *:*:::*: ** **::**:*:.:*: .: * . :. :: :*.**** :*:*: ::* *.*:***:* ::***::**::** :. : : . * **: .: ::* ***. : *::. : ******: * *** ** *** . ***:**** ***:*... :.:*::* :*** **: *:.*:: ... :**:.******::*:::::**** :***:** ** * : *. : :*::: : .. :..*:::* ***.:.*::* * ***::***** * **:** ::**. ", "identical_positions": 168, "similar_positions": 174, "identity": "30.11%" }, { "cls_id": "homologset.agr.MGI:2139270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF41-1", "uniprot_id": "SNPH_RAT", "id": "B5DF41-1", "name": "Syntaphilin", "aln": "------------------------------------------------------------------------MAMSLQGSR-----RASAGSRRRTSPPVSVRDAYGTASLSSSSNSGSCKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGVAKE-----------------EGTGESAGGSPARSLTRSSTYTKLSD---PAVCGDRQAGDPSNTPAEDRADSGFVAADDT---LSRTEALEASSLLSSGVDCGFEEAS--LHSSFNLGPRFPASNTYEKLLCGMEAAVQASC--------------MQERAIQTDF-------------VQYQPDLNTILEKVGQAQGCSS---VLKDRHSELDLHPSGPRDPDSAVVVTVGDEP------------------------------EAP--------------------------EPITRGPAIHRPAVN--SNPGLPVSVVCPVEEEEEAAAAAAAA---------------------AAATTTTTTTEKEPKS---------YWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISC-SLSQPSAGSSGG-SQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U23-1", "uniprot_id": "SNPH_MOUSE", "id": "Q80U23-1", "name": "Syntaphilin", "aln": "------------------------------------------------------------------------MAMSLQGSR-----RASAGSRRRTSPPVSVRDAYGTSSLSSSSNSGSCKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGVAKE-----------------EGTGESAGGSPARSLTRSSTYTKLSD---PAVCGDRQPGDPSNTSAEDGADSGYVAADDT---LSRTDALEASSLLSSGVDCGLEEAS--LHSSFNLGPRFPASNTYEKLLCGMEAGVQVSC--------------MQERAIQTDF-------------VQYQPDLNTILEKVGQAQVCGS---VLKDRHSELDPHPSGPRDPDSAVVVTVGDEL------------------------------EAP--------------------------EPITCGPATHRPAVN--SNPGLPVSVVCPVEEEEEEAAAA-------------------------------TTTEKEPKS---------YWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLGQPSSSTAGG-SQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15079-1", "uniprot_id": "SNPH_HUMAN", "id": "O15079-1", "name": "Syntaphilin", "aln": "------------------------------------------------------------------------MAMSLPGSR-----RTSAGSRRRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGMAKE-----------------DGTGESAGGSPARSLTRSSTYTKLSD---PAVCGDRQPGDPSSGSAEDGADSGFAAADDT---LSRTDALEASSLLSSGVDCGTEETS--LHSSFGLGPRFPASNTYEKLLCGMEAGVQASC--------------MQERAIQTDF-------------VQYQPDLDTILEKVTQAQVCGTD-PESGDRCPELDAHPSGPRDPNSAVVVTVGDEL------------------------------EAP--------------------------EPITRGPTPQRPGAN--PNPGQSVSVVCPMEEEEEAAVAE-----------------------------------KEPKS---------YWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z3Z2-1", "uniprot_id": "A0A8M6Z3Z2_DANRE", "id": "A0A8M6Z3Z2-1", "name": "", "aln": "MHGCTTPASTQIHPILISTVYSKKHSFKYIYTIQVKMNFRCVPICVTMPSCLWVSFDYCRFIELDYTPMESGIMVSMRQSRGFLTPKSPERHCRRSPAPVSNRDPYGNASLSSSSNSGSCKGSDGSPTHRRHIKYTSCNDNHGIRPPPPEQYLTPLQQKEVCIRHLRARLKETIERLQDRDSEIDELRTQLTRMQEDWIEEECHRVEAQLALKEARREIHQLKEVVDVVKSSLGDTDTGVQKGFQDINLQNHKLESLLQSMELAQIGTTKTGEALAGGGLVGAGLEVSEGLAGSSEGSPARSLTRSSTYTKLSDQGGPERESNENGCDIPCLSGEGTQDSGFVCCGESGRGASKADLLLEAAFLSQETASLLNAYSRLPHSSTYEGLCSSEPRVVPLRCSSIGAGASVSLSHPCLSHHHLYLHHLREQGIQTEYDHAPASAPAHGPSTSFNSDLDTIAERTFRSQACSPTSTWMSDEGDDLESAATESAITATVATTSVVADFSTKSAPVAMGNWMPTASDSKGAATFPLMPIDSPDKETSFSEPLTDLPISTTALTTETIGSPVTNSTVQPQPITDPLPNPGTSPCSMQPLVGTEEDSLPQTTQPHSVLTETVVPGDNVINIGADDEDEGDEGATNTDSKSSGCGLPVKNYWSRHFLVDLLAVVVPVVPTVAWFCRGPHRDGQPIYHIGSLLRGCCTVALHSLRRGGGLRHYPAGGGGPGGMNI-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: ** ::. **:..*** **.**.:********** ****.*** ** :*** *.*****:**.******************:****:* :******:***:*:***:************************:**:***:*:*.**..* *.*.*:** * ***:**:***:**:***:** * :* :* . *: ****************** * .:.: * . ..*. ***:....:: *::: * :::**. . . : * *** * . ... ..: *....* ::*:.***:: ..::.**:** *:. ::* *.. *. :*: .: . . :....:* : ::* .*:* ... :* .: .*** . . : *: ** : . .:.** *****::*********.******:**. :*:*****:*.*************:** . .. . .** . ", "identical_positions": 244, "similar_positions": 147, "identity": "33.61%" }, { "cls_id": "homologset.agr.MGI:2139274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAK9-1", "uniprot_id": "A0ABK0LAK9_RAT", "id": "A0ABK0LAK9-1", "name": "Zinc transporter ZIP12", "aln": "MCFWTELSVWVVLVSHSFSLASSTETSKALTQDN-SRVGSHSLLEVLRVLSAGDDRSLNHPQSLIKILLERTGCPQRTDGTQEDCKLCLEPDALSLTAGGDLEDELREEVVQRVSLLLLYYIIHQEEICSSKLNMSNREYEFYLHSLLSLRQDEDSYFLSEKETDDILASTRKYFGTSTSPCMETKILQRESGIQSSNGADEKMLPQLAATIIALSLQGVCLGRKDSPSPDDFTEYIFSFLNRTNALHLSELEELLNMLSTRRACTKIN-TLHEHQRKQN-TAVHGLRDPKSAAAMDKVSGDHSVSWDQACFSAQQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQVPRDQKAKPPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEA-ELGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILLVSPN-TKGLPLVNGHAGHTHHLGLSPELNDQSGGGKSISTIQLKGPEDSQTAELPKGNVPASNRNRKTISLLAVMVLVGDGLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSIRTAILMNFLSALTAFIGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMGSCFWKGWLYRPLVLELQNLNHLALFLNVETVNLNSGSHACSKSPLPWSMSPESEIWISS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWH7-1", "uniprot_id": "S39AC_MOUSE", "id": "Q5FWH7-1", "name": "Zinc transporter ZIP12", "aln": "MCFWTNLSVWMILLSHSLSLVSSTETGKTLTQNN-SRAGSQGLLEVLRVLSAGDHWSLNHPQSLIKILLERTGCPQRTDWTQGDCKLCLEADALLLTAGGNLEDELREEVVQRVSLLLLYYIIHQEEICSSKLNMSNREYEFYLHSLLGLRQDEDSYFLSEKETDDILAFTRKYFGTSSSQCMETKILQRESGIQGSNGADEKTLPQLAATIIALSLQGVCLGRKALPSPDDFTEYIFSFLNSTNTLHLSEIEQLLNMLTTRRTCAKEDKYLHQYQRKQN-TEEHSLRDPKTSTAMDKESDDHSPSWDQACFSARQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQMPKDQQAKPPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEA-EFGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILLVSPN-TKGLPLVNEHVGHTHHLGLNPELNDQSSGGKSISTIQLKGPEDSQTTVLPIGNVPASNRNGKTISLLAIMILVGDSLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSVRTAILMNFLSALTAFAGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGM----------LPEMTHVQTQRPWMTFL-LQNVGLVLG-----WFSLLLLAVYEQNIKI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q504Y0-1", "uniprot_id": "S39AC_HUMAN", "id": "Q504Y0-1", "name": "Zinc transporter ZIP12", "aln": "MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNHSRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNE-KIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSL-ISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEM----------LPEMTHVQTQRPWMMFL-LQNFGLILG-----WLSLLLLAIYEQNIKI--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:*** : : :* . ****.*. :*:. ** .* ::*:******. . **.:**** ***:****:* : * **:**:*.*** * ***::**:********************************:**:*******.******* ***::**:**** **:**.** * ***** **::*** .*:**:*. ****** **:*********: **** ******* ** **:*:***:::*** * ** :* * : :*:.***** *. .: :::*:* * * . ****:****:********: ** ********:*************::*:**:** ************************************** ********************************** *:******:. ****:**:******************** .:**.*** *.**:***.*..**.**:. *** ******.*****:: :* *.:.****: *:*****:*:****.********.**:***** *******************************::*******:*:**** ************ *****:************* * * : .:*. . ** ::...* * .* *.:* * ", "identical_positions": 481, "similar_positions": 117, "identity": "67.65%" }, { "cls_id": "homologset.agr.MGI:2139279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYN8-1", "uniprot_id": "HRH3_RAT", "id": "Q9QYN8-1", "name": "Histamine H3 receptor", "aln": "MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGRE-AGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58406-1", "uniprot_id": "HRH3_MOUSE", "id": "P58406-1", "name": "Histamine H3 receptor", "aln": "MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGRE-AGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5N1-1", "uniprot_id": "HRH3_HUMAN", "id": "Q9Y5N1-1", "name": "Histamine H3 receptor", "aln": "MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPP-PPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** :****:*******************************************************************************************************:**.********************************** ******************************************************************************.** *******:******* **.***** *****************. *.*:*** ****.***:.*******************************************:*********:*******:************************:*:***************************:****************:***.***:***", "identical_positions": 417, "similar_positions": 22, "identity": "93.5%" }, { "cls_id": "homologset.agr.MGI:2139287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNM4-1", "uniprot_id": "A0ABK0LNM4_RAT", "id": "A0ABK0LNM4-1", "name": "", "aln": "MPRSFLVKKIKAD---------------------------------------------------------------------------------------------GFQCSG---------VPAPTYHPLETAYVLPG-----------------------------------------TRGPPGDNGYVAHCMPPSG--------------------------------------------------YDGEQKPG-------------------LELAPTEPAYPAAASEEYSDPESPQ-------------------------------------SSLSARYFRGEAAVTDSYSMDAFFISDGRSRRRRAGAGG----------------------------DAAGAGD------GGGGGE--------------RAGRS--------GATAGGG-------HRHACAECGKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHVLTHNLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKHCEAACVKAAE-----------------------PPP----------SAGPAS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTH6-1", "uniprot_id": "SCRT2_MOUSE", "id": "Q8BTH6-1", "name": "Transcriptional repressor scratch 2", "aln": "MPRSFLVKKIKAD---------------------------------------------------------------------------------------------GFQCSG---------VSAPTYHPLETAYVLPG-----------------------------------------TRGPPGDNGYVAHCLPPSG--------------------------------------------------YDGEQKPG-------------------LELAPAEPAYPAAASEEYSDPESPQ-------------------------------------SSLSARYFRGEAAVTDSYSMDAFFISDGRSRRRRAGAGG----------------------------DAAGAGDAGGGGGGGGGGE--------------RAGRS--------GATAGGG-------HRHACAECGKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHVLTHNLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKHCEAACVKAAE-----------------------PPP----------SAGPAS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ03-1", "uniprot_id": "SCRT2_HUMAN", "id": "Q9NQ03-1", "name": "Transcriptional repressor scratch 2", "aln": "MPRSFLVKKIKGD---------------------------------------------------------------------------------------------GFQCSG---------VPAPTYHPLETAYVLPG-----------------------------------------ARGPPGDNGYAPHRLPPSS--------------------------------------------------YDADQKPG-------------------LELAPAEPAYPPAAPEEYSDPESPQ-------------------------------------SSLSARYFRGEAAVTDSYSMDAFFISDGRSRRRRGGGGG----------------------------DAGGSGD------AGGAGG--------------RAGRA--------GAQAGGG-------HRHACAECGKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHLLTHNLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKHCEAACAKAAE-----------------------PPPPT--------PAGPAS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZK2-1", "uniprot_id": "Q9VZK2_DROME", "id": "Q9VZK2-1", "name": "Transcriptional repressor scratch 1", "aln": "MPRCLIAKKWKAYPWLDRTEDTSNQQQQQEQSAPNSPRELEELHLKSRRSTLDDDEEIDVVGDKFLIKLEKQRTTADAAAAAATSSEAATSHSSNSSNMEASATTTTSKCWGPSSPTAGTTAPSPPPHSPEAATRVAGNVYNGYTRELSPLHYTAYLPRMESEITVIRAAATALVAARTSGNGSGDQHLAAYQTPPSSTTSSPSCSPSGAGDRYSPLSSGQTSSERKCFSSTGATLSLPPKKKDIYRPYSLDDKPAHGYRRRVPAEEDLHAAHAILDLSASTAFHPPTQPHQLQQQQQQQQQQHQHHHSQQQHLAPQQHHYLPLQQQQQQQAHHTHLPTLEAHAHLRSTSSIAELAAAASVVNEQRPASNASSASSNHMPSSPSSNSSSSSSQVQNENSNTTNTNPDGDGCLQDGEHSGASGASAKTVAYTYEAFFVSDGRSKRKHVADPAAAASGVPTPDQQKTKYTCSECGKQYATSSNLSRHKQTHRSLDSQSAKKCHTCGKAYVSMPALAMHLLTHKLSHSCGVCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRSNLRAHMQTHSVDKNFECKRCHKTFALKSYLNKHLESACLKDEEELMMSMSLSMHDSNSESGASMASSPPHEFLERVKLEGSGGATYAM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.::.** *. :* * ..:*. *. *:* :.* : . .**: ..: ***. *. ::**. *:*:.: . :*.: ..: .: :. * .:*.*: . .:: . : * .:.: *. . ..... :. * * .*..* **: .* *.* :::*:**** ******************** *:** ***************:***:* *.****** **********:********:***********************. *::.*::*.*:*******:** *:** * * .** :* *: ", "identical_positions": 155, "similar_positions": 93, "identity": "23.74%" }, { "cls_id": "homologset.agr.MGI:2139309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUD1-1", "uniprot_id": "A0A8I5ZUD1_RAT", "id": "A0A8I5ZUD1-1", "name": "GTPase-activating Rap/Ran-GAP domain-like protein 3", "aln": "MEQEPGGAAAALLRQKRAALRRRGCSFESPRCCGRPKPRPCDRPCTPQLREVLGCGECYLPASKFSRTSTAPQPPGPLMDPLTKGSCGSQLAQTLLWKAKSSLSFGIQPLQTWPTKDPELESQVNLSVSEDLGCRRGDFSRKHYGSVELLISSDADGAIQRAGRFRVENGSTDENAAALPGTWRRTDVHLENPEYHTRWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRVPQYRAILWRKTGTQKICLPYSPTKTLSVKSILSAMNLDKFEKGPREIFHPEIQKDLLVLEEQEGSVNFKFGVLFAKDGQLTDDEMFSNEIGSEAFQKFLNLLGDTITLKGWTGYRGGLDTKNNTTGINSVYTVYQGHEVMFHVSTMLPYSKENRQQVERKRHIGNDIVTIVFQEGEESSPAFKPSMIRSHFTHIFALVRYDQQNDNYRLKIFSEESVPLFGPPLPSPPVFTDHQEFRDFLLVKLINGEKATLETPTFAQKRRRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPESPKSARKKEEARQAEFVRIGQALKLKSIVRGDAPSSLAASGICKKEPWEPQCFCCNFPHEAVCADPWGQALLVSTD-AGVLLVDDD--LPSVPVFDRTLPVKQIHVLETLDLLVLRADKGKDARLFVFRLSAVQKGLDGRQTGRSRSDCRENKLEKTKGCHLYAINTHHSRELRIVVAIRNKLLLITRKPHNKPSGVPGTSLLSPMSESPVEEFQYIREICLCDSPAVMALVDGPTEESDNLICVAYRHQFDVVNESTGEAFRLHHVEANKVNFVAAVDVYEDGEAGLLLCYNYSCIYKKVCPFNGGSFLLQPSASDFQFCWNQAPYAIVCAFPYLLAFTTDSMEIRLVVNGNLVHTAVVPQLQLVASRSDIYFTAATTVHEGSSGGSSKGASAHTSPQTPPARDTPLFPSSLGEGEIQSKNLYKIPLRNLVGRSIERPLKSPLVSKVITPPTSIGLG-VAAIPVTHSLSLSRMEIKEIASRTRRELLGLSDDGGPKSEGAPRAKSKTRKRLEESQGSPKPETMRSASSDRIPSGVLESP-ASEAIPEGQNHSTSSEQDPVLDKEGSPGTGSSPFQLTASSEEDIIDLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V0G7-1", "uniprot_id": "GARL3_MOUSE", "id": "Q3V0G7-1", "name": "GTPase-activating Rap/Ran-GAP domain-like protein 3", "aln": "------------------------------------------------------------------------------MDPLTKGSCGSQLAQTLLWKAKSSLSFGIQPLQTWPTKDPELESQVNLSVSEDLGCRRGDFSRKHYGSVELLISSDADGAIQRAGRFRVENGSTDESAAALPGTWRRTDVHLENPEYHTRWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRVPQYRAILWRKTGTQKICLPYSPTKTLSVKSILSAMNLDKFEKGPREIFHPEIQKDLLVLEEQEGSVNFKFGVLFAKDGQLTDDEMFSNEIGSEAFQKFLNLLGDTITLKGWTGYRGGLDTKNNTTGINSVYTVYQGHEVMFHVSTMLPYSKENRQQVERKRHIGNDIVTIVFQEGEESSPAFKPSMIRSHFTHIFALVRYDQQNDNYRLKIFSEESVPLFGPPLPSPPVFTDHQEFRDFLLVKLINGEKATLETPTFAQKRRRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPESPKSARKKEEARQAEFVRIGQALKLKSIVRGDAPSSLAASGMCKKEPWEPQCFCCNFPHEAVCADPWGQALLVSTD-AGVLLVDDD--LPSVPVFDRTLPVKQIHVLETLDLLVLRADKGKDARLFVFRLSAVQKGLDGRQTGRSRSDCRENKLEKTKGCHLYAINTHHSRELRIVVAIRNKLLLITRKPHNKPSGVPGVSLLSPLSESPVEEFQYIREICLCDSPAVMALVDGPTEESDNLICVAYRHQFDVVNESTGEAFRLHHVEANKVNFVAAIDVYEDGEAGLLLCYNYSCIYKKVCPFNGGSFLLQPSASDFQFCWNQAPYAIVCAFPYLLAFTTDSMEIRLVVNGNLVHTAVVPQLQLVASRSDIYFTAATTVHEGSSGGSSKGASAHTSPQTPPARDTPLFPSSLGEGEIQSKNLYKIPLRNLVGRSIERPLKSPLVSKVITPPTSIGLG-VAAIPVTHSLSLSRMEIKEIASRTRRELLGLSDDGGTKTEGAPRAKSKTRKRLEESQGGPKPETVRSASSDRIPSGILESP-ASEANPEGHNHWASSEQDAGVDKEGSPGSGSSPFQLMASSEEDIIDLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VVW2-1", "uniprot_id": "GARL3_HUMAN", "id": "Q5VVW2-1", "name": "GTPase-activating Rap/Ran-GAP domain-like protein 3", "aln": "---------------------------------------------------------------------------------MVVDFCRRFVAR----------SLCIILMKHFCSS----------SVSEDLGCRRGDFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENATALPGTWRRTDVHLENPEYHTRWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRVPQYRAILWRKTGTQKICLPYSPTKTLSVKSILSAMNLDKFEKGPREIFHPEIQKDLLVLEEQEGSVNFKFGVLFAKDGQLTDDEMFSNEIGSEPFQKFLNLLGDTITLKGWTGYRGGLDTKNDTTGIHSVYTVYQGHEIMFHVSTMLPYSKENKQQVERKRHIGNDIVTIVFQEGEESSPAFKPSMIRSHFTHIFALVRYNQQNDNYRLKIFSEESVPLFGPPLPTPPVFTDHQEFRDFLLVKLINGEKATLETPTFAQKRRRTLDMLIRSLHQDLMPDLHKNMLNRRSFSDVLPESPKSARKKEEARQAEFVRIGQALKLKSIVRGDAPSSLAASGICKKEPWEPQCFCSNFPHEAVCADPWGQALLVSTD-AGVLLVDDD--LPSVPVFDRTLPVKQMHVLETLDLLVLRADKGKDARLFVFRLSALQKGLEGKQAGKSRSDCRENKLEKTKGCHLYAINTHHSRELRIVVAIRNKLLLITRK-HNKPSGVTSTSLLSPLSESPVEEFQYIREICLSDSPMVMTLVDGPAEESDNLICVAYRHQFDVVNESTGEAFRLHHVEANRVNFVAAIDVYEDGEAGLLLCYNYSCIYKKVCPFNGGSFLVQPSASDFQFCWNQAPYAIVCAFPYLLAFTTDSMEIRLVVNGNLVHTAVVPQLQLVASRSDIYFTATAAVNEVSSGGSSKGASARNSPQTPPGRDTPVFPSSLGEGEIQSKNLYKIPLRNLVGRSIERPLKSPLVSKVITPPTPISVG-LAAIPVTHSLSLSRMEIKEIASRTRRELLGLSDEGGPKSEGAPKAKSKPRKRLEESQGGPKPGAVRSSSSDRIPSGSLESASTSEANPEG--HSASSDQDPVADREGSPVSGSSPFQLTAFSDEDIIDLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF44-1", "uniprot_id": "GARL3_DANRE", "id": "A5PF44-1", "name": "GTPase-activating Rap/Ran-GAP domain-like protein 3", "aln": "------------------------------------------------------------------------------MNSDINMYLGREKAG--------IMRKRALLLRKGCSFEITS------SASEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSIDEISDYTPGTWRRTDVHLENPEYHTRWYFKYFLGKVHQNYVGTDAEKNPFFLSVVLSDQNNQRVPQYRAILWRKTGTLKISLPYSPTKTLSVKSILSAMNVDRFEKGPREILNPEIQKDLLVLEEQEGSVNFKFGVLYAKDGQLTDDEMFSNEMGSETFEKFLNLLGDTICLQGWAGYRGGLDTKNDTTGINSIYTVYQGHELMFHVSTMLPYSKENKQQVERKRHIGNDIVTIVFQEGDDASPSFKPSMIRSHFTHIFALVRYNSQNDSYRLKIFSEESVPLFGPPLPSPPVFTDHQEFRDFLLVKLINGEKATLETPTFAQKRQRTLDMLIRSLYQDLMPDMHKNMLNRRSFSDVLPESPKSARKKEEARQAEFVRVGQALKLKTIVRGDAPTSLVTTGLCRKEPWESQSFCSSFPYDIVCGDSWGQSLLVATDSAGVMLLEDSPTLPPVQVFDKTLTVKQMHVLEPQDLLIARADKGKDARLYVYRLSTLKQGIEERQLVRTKCDSRENKLEKTKGCHLYSINTHHGVELRIVAAIRNKLLLITRK-QSRLECVSSIATVTGSTDSPVEEFQYIREICLCDSPVVMALVDGPTGENDHMICVAYRHQFDLINESTGDAYRLHHVDSNRVNFVAAIDVYEDGEAGLLLCYNNICVYKKVCPFNGATPMIQPNTSDFHFSWNQMPNATVCAFPYILAFTTDSIEIRLVVNGNLVYTAVVPELQLTASRSDIYFISSAPINSASN-CSSRDTSSQSSPQTPTGYEMPVFPSPLGDGETQSKHIYKIPLSNLVGRSIERPLKSPLVNKVLTAPAPSMTGPAPMIGSTTSLSLSRMEIKEIASRTRKELLGLTEEPSSKADGNSVKQRRMSKKNKEEE---QKRTAEISIAEQVG--------MESVDGETDIQQLCPSGSEVEVRDDSPPTAN-PFTFSTSFEDDILDLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: : *.*********:********************************* ** : ***************************:*****:*.****.******.********************** **.*******************:*:********::************************:***************:***.*:********** *:**:**********:****:*:********:**************:*********************:::**:*******************:.***.*******************:***********************************:**********:******:**********************************:*******:*******:**.::*:*:*****.*.**..**:: **.*.***:***:** ***:*::*. **.* ***:**.***:****. ***: **********:*:***::::*:: :* :::.*.**************:*****. *****.************ :.: . *.. : :: ::**************.*** **:*****: *.*::**********::*****:*:*****::*:******:*************** *:*********.: ::**.:***:*.*** * * ******:*******:***********:*****:***.******** :::.::. *. **:.:*::.*****.. : *:***.**:** ***::***** ****************.**:*.*:. * . * * *****************:*****::: ..*::* . : : *: :*.: : : . : :::: ... * : ... . ::.** :.. ** : : ::**:***", "identical_positions": 713, "similar_positions": 192, "identity": "63.6%" }, { "cls_id": "homologset.agr.MGI:2139317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ARU5-1", "uniprot_id": "A2ARU5_MOUSE", "id": "A2ARU5-1", "name": "", "aln": "-MAKPTRRGNGTSSESLRQRFRRFHYQEVAGPREAFSQLWELCCRWLRPEVRTKEQIVELLVLEQFLTVLPVEIQNWVQKQCPENGEEAVTLVEDLERESGRPGHSVTVSVKGQEMHSEKMTPLKSSQELLSVLQESVEPQPKGVSKKERARRPALRLQEQMNPKENLRPFQRSGFPFPKPNVVSRLDQGEPWISDLLSSKEKDVPKG------NTGTSLLPSKRERTCWVEQGHWVFDDEKVVGVHWGYKETRTLLAILSQTEFYEALRNCHRNSQVYGAVAGRLREYGFLRTLEQCRTKFKGLQKSYRKVKSGHPPDTCPFFEEMEALMSAQVISLPINGLEEAASHSAQAGSDAETEKPGQRDWQHEDG-EEAIAERSDSD--DPEATPQDPDNPPAPVLFRSPSGVHWGYEETKTYLAILSETQFYEALQNCHRNSQLYGTVAERLWEYGFLRTPEQCRTKFKSLQTSYRKVKNGQALETCPFFEEMDALVSAQVAAPPSDDQEKETVSCCLQRTSEAEPEKQ----DEDTEEDSDD-EDDTEIPPEAVITRAPVLFQSPSGFEAGFENEENSKRDISEEVQLHRTLLARSERKISHHVNQSKASKNKCSSESQWEKTQREEQRQLAFPEKNIGKVLTYQRPGLEDRPYKYVKYGKSSGSNSHLRYPVSHEVENPYKCADCGKSFSRSARLIRHQRIHTGEKPYKCLDCGKGFRDSSNFITHRRIHTGEKPYQCDECGKRFNQSSSLIIHQRTHTGEKPYQCEECGKSFNNSSHFNAHRRIHTGERPHVCPDCGKSFSKSSDLHAHHRTHTGKKPYGCHDCGKCFSKSSALSKHRETHTREKLLS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWY8-1", "uniprot_id": "ZSC29_HUMAN", "id": "Q8IWY8-1", "name": "Zinc finger and SCAN domain-containing protein 29", "aln": "MMAKSALRENGTNSETFRQRFRRFHYQEVAGPREAFSQLWELCCRWLRPEVRTKEQIVELLVLEQFLTVLPGEIQNWVQEQCPENGEEAVTLVEDLEREPGRPRSSVTVSVKGQEVRLEKMTPPKSSQELLSVRQESVEPQPRGVPKKERARSPDLGPQEQMNPKEKLKPFQRSGLPFPKSGVVSRLEQGEPWIPDLLGSKEKELPSGSHIGDRRVHADLLPSKKDRRSWVEQDHWSFEDEKVAGVHWGYEETRTLLAILSQTEFYEALRNCHRNSQVYGAVAERLREYGFLRTLEQCRTKFKGLQKSYRKVKSGHPPETCPFFEEMEALMSAQVIALPSNGLEAAASHSGLVGSDAETEEPGQRGWQHEEGAEEAVAQESDSDDMDLEATPQDP-NSAAPVVFRSPGGVHWGYEETKTYLAILSETQFYEALRNCHRNSQLYGAVAERLWEYGFLRTPEQCRTKFKSLQTSYRKVKNGQAPETCPFFEEMDALVSVRVAAPPNDGQE-ETASCPVQGTSEAEAQKQAEEADEATEEDSDDDEEDTEIPPGAVITRAPVLFQSPRGFEAGFENEDNSKRDISEEVQLHRTLLARSERKIPRYLHQGKGNESDCRSGRQWAKTSGEKRGKLTLPEKSLSEVLSQQRPCLGERPYKYLKYSKSFGPNSLLMHQVSHQVENPYKCADCGKSFSRSARLIRHRRIHTGEKPYKCLDCGKSFRDSSNFITHRRIHTGEKPYQCGECGKCFNQSSSLIIHQRTHTGEKPYQCEECGKSFNNSSHFSAHRRIHTGERPHVCPDCGKSFSKSSDLRAHHRTHTGEKPYGCHDCGKCFSKSSALNKHGEIHAREKLLTQSAPK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.: * ***.**::****************************************************** *******:*******************.*** **********:: ***** ********* ********:**.****** * * ********:*:******:****..*****:******.***.****::*.* .. :.*****::* .****.** *:****.******:******************************** **********************************:*****************:** **** *****. .*******:****.****:* ***:*:.**** * ******* *..***:****.*************************:**********:************************************ **************.:*****.*.** **.** :* *****.:** ** ******* *:****** ************* *********:************************.::::*.*..:..* * ** **. *:: :*::***.:.:**: *** * :*****:**.** *.** * : ***:***********************:****************.**********************.**** ***********************************.***************************:********:******************.** * *:*****: ", "identical_positions": 694, "similar_positions": 96, "identity": "81.26%" }, { "cls_id": "homologset.agr.MGI:2139347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTK4-1", "uniprot_id": "E9PTK4_RAT", "id": "E9PTK4-1", "name": "", "aln": "MLSFTRCHHLKRITQKCFSSALVKVQTPTQLSLPRALACAESGKSWHSTHSLVGDKNIVLMGPPGAGKTTVGRILGDKLGCCVIDVDADVLEKTWNMSVSEKLQDVGNERFLEEEGKAVLNLFASGSVISLSGSNPMHDASMWHLKKNGIVVYLDVPLTDIISRLKSMRVDRIVGRNTGTSLRDLLKHGKLHYRKWYDARVFCESGASAEEVADKVLDVVKRYQDVDSETFISTRHVCLKDHDKKFPPKYFSEAVVEGLASDGGLFVPEKGFPKLSLGEWTNLIGATYIERAQVLLERCIHPADIPAAKLGEMIETAYGESFACSKVAPVRHLSG---NQFILELFYGPTGSFKDLSLQLMPHIFAYCIPPGCN---------YVLLVATSGDTGSAVLNGFSRLNRSDKERIAVLTFFPENGVSDFQRAEIVGSQRENGWAIGVKSDFDFCQAAIRKIFNDSDFTGFLTVEYGVVLSSANSINWARLLPQVVYHASAYLELVSQGFISFGSPVDVCIPTGNFGNILAAVYAKMMGIPIRKFICASNQNHVLTDFIKTGHYDLRNRRLAQTFSPSINILKSSNLERHLYLMANK---------DGQLMADLYNQLESQLHFQIEELLVEKLQQDFVADWCSEGECLEAISTTYNTSG----YILDPHTAVAKVVADKMQDK----SCPVVIASTAHYSKFAPVVLQALRIKELNQTSASQLYLLSSYNALPPPHEALLERMKQKGKMDYQACVADVDVLKSHVEKLIQSWFREV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH55-1", "uniprot_id": "THNS1_MOUSE", "id": "Q8BH55-1", "name": "Threonine synthase-like 1", "aln": "MLTLTRCHHLKQIAQECLSSLLVKVQSRTQLLLPRASARAESGKSWHSTHSLVGDKNIVLMGPPGSGKTTVGRILGDKLGCCVIDVDSDVLEKAWNMSASEKLQDVGNERFLEEEGKTVLNLSASGSVISLSGSNPMHDASMWHLKKNGIVVYLDVPLTDIISRLKSMRIDRIVGQNTGASLRDSLKHVRLYYKKWYDARVFCESGASAEEVADKVLDVVKRYQDVDSETFISTRHVCLKDHDKKFPPKYFSEAVVEGLASDGGLFVPEKEFPKLSPGEWNNLIGATYIERAQVLLERCIHPADIPAAKLGEMIETAYGENFACSKVAPVRHLSG---NQFILELFYGPTGSFKDLSLQLMPHIFAYCIPPGCN---------YVILVATSGDTGSAVLNGFSHLNKNDKERIAVVTFFPENGVSDFQKAEIIGSQRENGWAIGVRSDFDFCQTAIRKIFNDSDFTGFLAVEYGTILSSANSINWARLLPQIVYHASAYLELVNQRFISFGSPVDVCVPTGNFGNVLAAVYAKMMGIPIRKFICASNQNHVLTDFIKTGHYDLRNRKLAQTFSPSIDILKSSNLERHLYLMANK---------DGQLMANLYHQLESQLHFRIEKMLVEKLQQEFVADWCSEGECLAAISTTYNASG----YILDPHTAVAKVVADKMQDK----SCPVLIASTAHYSKFAPAIMQALGIKELNQTSSSQLYLLSSYNALPPPHEALLERMKQKEKMDYQVCVADVDVLKSHAEKLIQNWFVRKSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYQ7-1", "uniprot_id": "THNS1_HUMAN", "id": "Q8IYQ7-1", "name": "Threonine synthase-like 1", "aln": "MLHFNRCHHLKKITQKCFSSIHVKTDKHAQRFLSRTFALAELRKSWYSTHSLVGDKNIILMGPPGAGKTTVGRIIGQKLGCCVIDVDDDILEKTWNMSVSEKLQDVGNEQFLEEEGKAVLNFSASGSVISLTGSNPMHDASMWHLKKNGIIVYLDVPLLDLICRLKLMKTDRIVGQNSGTSMKDLLKFRRQYYKKWYDARVFCESGASPEEVADKVLNAIKRYQDVDSETFISTRHVWPEDCEQKVSAKFFSEAVIEGLASDGGLFVPAKEFPKLSCGEWKSLVGATYVERAQILLERCIHPADIPAARLGEMIETAYGENFACSKIAPVRHLSG---NQFILELFHGPTGSFKDLSLQLMPHIFAHCIPPSCN---------YMILVATSGDTGSAVLNGFSRLNKNDKQRIAVVAFFPENGVSDFQKAQIIGSQRENGWAVGVESDFDFCQTAIKRIFNDSDFTGFLTVEYGTILSSANSINWGRLLPQVVYHASAYLDLVSQGFISFGSPVDVCIPTGNFGNILAAVYAKMMGIPIRKFICASNQNHVLTDFIKTGHYDLRERKLAQTFSPSIDILKSSNLERHLHLMANK---------DGQLMTELFNRLESQHHFQIEKALVEKLQQDFVADWCSEGECLAAINSTYNTSG----YILDPHTAVAKVVADRVQDK----TCPVIISSTAHYSKFAPAIMQALKIKEINETSSSQLYLLGSYNALPPLHEALLERTKQQEKMEYQVCAADMNVLKSHVEQLVQNQFI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16120-1", "uniprot_id": "THRC_YEAST", "id": "P16120-1", "name": "Threonine synthase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNASQVYRSTRSSSPKTISFEEAIIQGLATDGGLFIPPTIPQVDQATLFNDWSKLSFQDLAFAIMRLYIAQEEIPDADLKDLIKRSYSTFRSDEVTPLVQNVTGDKENLHILELFHGPTYAFKDVALQFVGNLFEYFLQRTNANLPEGEKKQITVVGATSGDTGSAAIYGLR-----GKKDVSVFILYPTGRISPIQEEQMTTVPDENVQTLSVTGTFDNCQDIVKAIFGDKEFN------SKHNVGAVNSINWARILAQMTYYFYSFFQATNG---KDSKKVKFVVPSGNFGDILAGYFAKKMGLPIEKLAIATNENDILDRFLKSGLYERSD-KVAATLSPAMDILISSNFERLLWYLAREYLANGDDLKAGEIVNNWFQELKTNGKFQVDKSIIEGASKDFTSERVSNEETSETIKKIYESSVNPKHYILDPHTAVGVCATERLIAKDNDKSIQYISLSTAHPAKFADAVNNALSG-------------FSNYSFEKDVLPEELKKLSTLKKKLKFIERADVELVKNAIEEELAKMKL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :* . ... . *.**:::***:*****:* . . :.. :: : * ::. * :** * * ::*: :*. : . . *::::* * .*****:*** :***::**:: ::* : : :: *********.: *: .*: ::*. ::* . :* :*. :: ** ::.* . ** ** :: **.*.:*. :.:.*****.*:*.*:.*: :::: .. . .. *.. :*:****::**. :** **:**.*: *:*:*.:* *:*:* *: : ::* *:**:::** ***:** * :*.: *::: : ::.*::: :*:::: ::* .::*.:: *: * :*.. *::* *********. .:::: * : : **** :*** .: :** :..*. *:: . * **::::*. *: : . ", "identical_positions": 145, "similar_positions": 182, "identity": "18.69%" }, { "cls_id": "homologset.agr.MGI:2139354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A5R2-1", "uniprot_id": "BIG2_MOUSE", "id": "A2A5R2-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "aln": "MQES---------------------------QTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQ-------RLGAAAPPK-----ANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQ---TDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPMQ------------SKPQSPVIQAT-------AGSPKFSRLKQSQ----------AQSKPTTPEKAELPNGD---------------------------------HAQSGLGKVSLENGEAPRERGSPVSGRAEPSRGTDSGAQEVVKDILE----------DVVTSAVKEAAE-KHGLPEP--DRALGALECQECAVPPGVD--ENSQTNGIADDRQSLSSADNLEPD-VQGHQVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSH---------EMFVTAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGH---------------------------------------ELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQATLGQERLPDQEMGDGKGLD--MARRCSVTS---------VESTVSSGTQTAIQDDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLG-AAVEDIAQFLHQEERLDSTQVGEFLGDSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSSIYDEIEGKKIAMKETKEHTIAT--------KST-KQSVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAP---FTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREG-------SLKGHSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQMVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYT----SDDMNVAPGDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFR-IVFRIFDNMKLPEQQ------SEKSEWMTTTCNHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHVLLTWRPAGM-------EEEVSD-RHLDVDLDRQSLSSIDRNASERGQSQLSNPTDDSWKGA---PYAHQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAE--------IHIETE-------NQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWDEIQQRLLRVCSEALAYFITVNS---ESHREAWTSLLLLLLTKTLKISDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGLVYKIWIPEEPSQVPAALSSTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSU1-1", "uniprot_id": "BIG2_RAT", "id": "Q7TSU1-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "aln": "MQES---------------------------QTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQ-------RLGAAAPPK-----ANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETVCNCFQGPQ---TDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPIQ------------SKPQSPVIQAT-------AGSPKFSRLKQSQ----------AQSKPTTPEKTELPNGD---------------------------------HARSSLGKVNSENGEAHRERGSSISGRAEPSGGSDNGAQEVVKDILE----------DVVTSAVKEAAE-KQGLPEP--DQAPGVPECQECTVPPAVD--ENSQTNGIADDRQSLSSADNLEPD-AQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSH---------EMFVTAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGH---------------------------------------ELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQATLGQERLPDQEMGDGKGLD--MARRCSVTS---------VESTVSSGTQTAIPDDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLG-AAVEDIAQFLHQEERLDSTQVGEFLGDSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSSIYEEIEGKKIAMKETKEHTMAT--------KST-KQNVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAP---FTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREG-------SLKGHSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQMVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYT----SDDMNVAPGDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFR-IVFRIFDNMKLPEQQ------SEKSEWMTTTCNHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFRTTIPHVLLTWRPAGM-------EEEVSD-RHLDVDLDRQSLSSIDRNASERGQSQLSNPTDDSWKGA---PYANQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAD--------IHIETE-------NQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWGEIQQRLLTVCSEALAYFITVNS---ESHREAWTSLLLLLLTKTLKINDEKFKAHASVYYPYLCEMMQFDLIPELRAVLRKFFLRIGLVYKIWVPEEPSQVPAAS-TAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6D5-1", "uniprot_id": "BIG2_HUMAN", "id": "Q9Y6D5-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "aln": "MQES---------------------------QTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAEIEKQ-------RLGTAAPPK-----ANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICSCFQGPQ---TDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPIQ------------SKPQSPVIQAA-------AVSPKFVRLKHSQ----------AQSKPTTPEKTDLTNGE---------------------------------HARSDSGKVSTENGDAPRERGSSLSG-------TDDGAQEVVKDILE----------DVVTSAIKEAAE-KHGLTEP--ERVLGELECQECAIPPGVD--ENSQTNGIADDRQSLSSADNLESD-AQGHQVAARFSHVLQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTH---------EMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGH---------------------------------------ELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERLTDQEIGDGKGLD--MARRCSVTS---------MESTVSSGTQTTVQDDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLG-TSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSSIYEEIEGKKIAMKETKELTIAT--------KST-KQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAP---FTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREG-------SLKGHTLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMAIRCIAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTCHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYT----SDDMNVAPGDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFR-IVFRIFDNMKLPEQL------SEKSEWMTTTCNHALYAICDVFTQFYEALNEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPEVWDETCNCMLDIFKTTIPHVLLTWRPVGM-------EEDSSE-KHLDVDLDRQSLSSIDKNPSERGQSQLSNPTDDSWKGR---PYANQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAD--------IHIETE-------DQGMYKYMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNS---ESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQVPAALSPVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCG1-1", "uniprot_id": "E7FCG1_DANRE", "id": "E7FCG1-1", "name": "", "aln": "MKEQEALA------------THRRHTQTESLSTKSMFLSRALEKILADKEVKRSQHNQLRKACQVALDEIKHELEKQ-------KDGTVVPPR-----ANYIEADKYVLPFELACQSKSPRIVSTSLDCLQKLIAYGHITGNAPDSAAPGKRLIDRLVETICNCFQGPQ---TDEGVQLQIIKALLTAVTSPHIEIHEGTILLTVRTCYNIYLASRNLINQTTAKATLTQMLNVIFTRMENQAALEAQEAEKERQRLQLRNPSPV--SSNPSPVNQNPSQTPGRGSGSPWMGRACSEQNGSPCLSPPGVPSTPSTPQDSSSINSRP--------------------------------EEEFATDKQSTKDITHPDEELQESDQTTVDPSVTGGVEGEETHPQSE----------TEAGSEVLEETEPDSGLGDSSVEGGLDQHSDSETRMPPPVVRVDTQQMNGMVDDRGSESSTDMLDAESIHGSQTAARFSHILQKDAFLVFRSLCKLSMKPLADGPPDPKSHELRSKVVSLQLLLSVLQGAGPVFRTH---------EMFVNAIKQYLCVALSKNGVSSVPEVFELSLAIFLTLLSHFKVHLKMQIEVFFREIFLTILETSSSSFEHKWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGQ---------------------------------------ELGMTPLQELSLRKKGLECLVSILKCMVEWSRDMYVNPNLQANLGQERPAEGDSADVKLSEHLSSRRDSVSS---------LDSTVSSGVQQSQPDHPEQYEVIKQQKEIIEHGIELFNKKPKRGLQYLQEQGMLG-TSPEDIAQFLQQEERLDTTQVGEFLGENVKFNKEVMYCYVDRLDFCGKDFVSALRAFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSSIYDEIAGKKIAMKESKEYSITP--------KSS-KQNVANEKQRRLLYNMEMEQMAKTAKALMEAVSHAQAP---FFSATHLEHVRPMFKLAWTPLLAAFSVGLQDCDDQDVASLCLEGIRCAIRIACIFNMQLERDAYIQALARFTLLTASSSITEMKQKNIDTIKTLIMVAHTDGNYLGNSWHEILRCISQLELAQLIGTGVKMR-ISGVVRDQGG-------GIKGFPSGGEEFMPLGLGTLVGG-PDKRQMAHIQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---AHQPRMFSLQKIVEISYYNMNRIRLQWSRIWQVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIVKKNRSPTIRDMVIRCVAQMVNSQAANIRSGWKNIFSVFHQAASDHDENIVDLAFQTTGHIVMNTFQQHFAAAIDSFQDAVKCLSEFVCNAAFPDTSMEAIRLIRHCAKYVSERPQALREYT----SDDMNVAPGDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWHDLFR-IIFRIFDNMKLPEQQ------TEKTEWMTTTCNHALYAICDVFTQFYEPLSEVLLADIFAQLQWCVKQDNEQLARSGTNCLENLVILNGEKFSPEVWDVTCSCMLDIFQTTSPHALLTWRPAGQ-------EEEVGEGKHMDVEVDSQSQSSFERTLSERGHSQMSTASDETWKGKSHTRVSDHRLFAGLLIKCVVQLELIQTIDNIVFYPATSKREDAENMAAAQRDALEQA--------EEGEAEV------DQGMYRHLSSQHLFKLLDCLLESHRFAKDFNSNNEQRTALWRAGFKGKSKPNLLKQETSSLACSLRILFRMYSDTQLRDSWPDIQTRLLHVCSEALAYFISLTS---ESHREAWTSLLLLLLTRTLRLPDDKFKPHASCYYHHLCEMMQFDLIPELRAVLRRFFLRIGSVFHIAAPELGQAQPSSSSSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJW1-1", "uniprot_id": "Q9VJW1_DROME", "id": "Q9VJW1-1", "name": "", "aln": "MHNN-------------------------STKTKEMFIVRALEKILADKDIRRSHHSQLKKSCDSALEQIKAELISAGQIAEGNELPCAALPLPKNDAASIINAETYFLPFELACKSRSPRIVVTALDCLQKLIAYGHLTGSIQDSANPGHLLIDRIVVTIYGCFSGPQ---TDEAVQLQIIKALLTVVTSQHVEIHEFTLLQAVRTCYDIYLSSKNLVNQTTARATLTQMLNVIFARMENQVYELP--------------------------------------------------------------------PPNSNPTNGS-----------------------------------------IHSEDCNGSGEES------------LRDSDEVIASELLA----------EIISAAYNEAMKDQESVGEP------------EPTLN--------------GNDYSSHSDHDSVELHSENDAVVTAKFTHILQKDAFLVFRALCKLSMKPLPDGHPDPKSHELRSKVLSLHLLLLILQNAGPVFRSN---------EMFIMAIKQYLCVALSNNGVSLVPEVFELSLSIFVALLSNFKVHLKRQIEVFFKEIFLNILEANSSSFEHKWMVIQALTRICADAQSVVDIYVNYDCDFSAANLFERLVNDLSKIAQGRQAL---------------------------------------ELGANPMQEKSMRIRGLECLVSILKCMVEWSKDLYVNPNMPVPPMQVQSPTSTEQDQADTTIQTMHSGSSHS---------LNS-----NQEQLQDLPEALEERKMRKEVMETGIELFNRKPQKGVQFLQEKQLLG-ATCGDIARWLHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKIDRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQA--------KPTGKQAFITEKRRKLLWNMEMEVISLTATNLMQSVSHVKSP---FTSAKHLEHVRPMFKMAWTPFLAAFSVGLQDCDDPEIATLCLDGIRCAIRIACIFHMSLERDAYVQALARFTLLNANSPINEMKAKNIDTIKTLIMVAHTDGNYLGSSWLDIVKCISQLELAQLIGTGVRPQFLSGAQTTLKD-------SLN---------------------------PSVKEHIGETSSQSVVVAVDRIFTGSMRLDGDAIVDFVKALCQVSVDELQ----QQQPRMFSLQKIVEISYYNMERIRLQWSRIWQVLGEHFNAVGCNSNEEISFFALDSLRQLSMKFMEKGEFSNFRFQKDFLRPFEHIMKKNASPAIRDMVVRCIAQMVNSQAHNIRSGWKNIFSIFHLAAGDNEEPIVELAFQTTGKIIGDLYKRQFAIMVDSFQDAVKCLSEFAT-ARFPDTSMEAIRLVRTCAQCVHEAPQLFAEHAG--MENDASVAEEDRVWVRGWFPMLFSLS-CVVNRCKLDVRTRALTVLFEIVKTYGESFKPHWWKDLFN-VIFRIFDNMKLPEHV------TEKSEWMTTTCNHALYAIIDVFTQYFDVLGHLLLEELFAQLHWCVQQSNEQLARSGTNCLENLVISNGFKFNESTWDKTCQCILDIFNATLPQDLLSWRPKAH-------SSNNIP--------------------------------------------QEHNHFEALHIRCVVQLELIQTMDNIVFFPATSRKEDAETLAQAAADLTGGR--------SGSQSQLLECQREEQGMYGYLRTRQLLTLADCLMQSHRFAKRFNADHDQRSLLWRAGFKGSVKPNLLKQETSSLACVLRIFFKMYGDENRRSDWPGIEQELVQVCKEALGYYLSLQS---EAHRDAWTSLLLLILTRLLKMSDARFATHVSNYYSLLCEMMCFDLKPELRSVLRRVFMRIGPVFNIMSVK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11075-1", "uniprot_id": "SEC7_YEAST", "id": "P11075-1", "name": "ADP-ribosylation factor guanine nucleotide-exchange factor SEC7", "aln": "MSEQNSVVNAEKGDGEISSNVETASSVNPSVKPQNAIKEEAKETNGEDQKCKGPENAGSTAETKETSNDATNGMKTPEETEDTNDKRHDDEGEDGDEDEDEDEDEDEDNGDEDDEDVDSSSSETSSEDGEDSESVSGESTESSSGEDEESDESDGNTSNSSSGDESGSEEEEEEEEEEEEEENAGEPAIAHQDSVPTNDSTAPRSTHTRNISLSSNGSNTNSTIILVKTTLETILNDKDIKKNSNAQKAIERTLQKFKEFDPQTTNNPHYVDSILVFEALRASCRTKSSKVQSLALDCLSKLFSFRSLDETLLVNPPDSLASNDQRQDAADGITPPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAIRTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIELSEASEN-AETPAPLTLENMDKLNDDEERLMDAQQPDSIAITNQDLAVKDAFLVFRVMAKICAKPLET-ELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSIRQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTTSTSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEITQTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFPLDFALKMVSLNCIVSVLRSLSSWAHKALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKPTYEDEESRSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPG--VFSKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGR-DLPRDFLEGLFNEIANNEIKLISEQHQAMLSGDTNLVQQQQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSIFETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQFCNLQN---LEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRDTVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFISSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVDVCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSGFEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTARSSTESIVLKTQLLVSNDIVTNHFENVFSQEDAFSELVGVFREITKNKRFQKLSLHALESLRKMTQNVADICFYNENKTEEERKHNDALLRGKDIFQDVWFPMLFCFNDTIMTAEDLEVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLSKHWEVNQFNSHDDLSVWLSTTLIQALRNLIALFTHYFESLNR-MLDGFLGLLVSCICQENDTIARIGRSCLQQLILQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHSDDDSNDRRENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELNPKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELFENEDFAHCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDK-IPNLLKQETSAAAVLLDIMFQLYLNDDEKK--ADLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQGYYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELYLSTD---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. ..:. : .* *. *:. : ..: . : :: . : . . : : * . *. :: * :. . *. * . .. .. .. : . .*.: :* : : :* ..:: . : : :* *:*.. .::* . * : .:: : :: * .: *. . * . : : . . . .. : :: . .. : . : : .: ******** :.*:. *** * :** :***::**::: :::. ** :: *: :*:*** :.**.*..* :. ***::* *: *::::: .: :* **: **:: * * .:*: ::: .:..: *** *.: :*::*:****: . .*::* *: *:::* * ::. : ::: .*:*:**:*:.: .*::. . . . . : : * :. * * * * * :* :. * :**.**::.: * :: :* : .**::* : * ** : :*:::*:. . :* .::* :** ..* *** :*:.******.*****:* *** *: : * :* .***.***::*:***.*****.*:*:**: ::::: *.**.:.: ***.::*..:::** ::* : . . . : : : . ... : :* : :: .: ::: :.: :. : :*.*::**:.:*: * .:*** : ::: ** : :. **:*:: :::**. * :. * ::: **.:* * : *:* **:::: *: ** ::**** .** :*: :**:* ***..*: :.. . . . * **..:** :*.*** * .*.*:*****:: * **::*: ********:*::.****:**:*:*: :* *:*. ** :. *.* : :**:********:*:: *::.*.**:***:***: :::. .. :::* :.*. ::: ::: .*:**** *: :: :* . ** : . : : . .:. *:*.: * : *:. * . *:.*:. :* : * : : : ..: : . :: ***:** :. ::. .*:**:*.*. :*: : :** .* .:*..: . ::* **. :. . : : *::** :** : :**:::: * . :* .:. * *: *.*: :** * .**::*:: * **. *: . : .:* * .: *: : * : : : .*: ** . .: : *.: : * : ::.: : :. : : * :*: *:: ** : *: * .* . .. *********: * * *:*::* : : :. : .*: :* :.: :::: . * :** *::: :* .: * * : . * : ::: .: .*** .:::.: *:* :: ", "identical_positions": 382, "similar_positions": 575, "identity": "18.76%" }, { "cls_id": "homologset.agr.MGI:2139360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDM1-1", "uniprot_id": "M0RDM1_RAT", "id": "M0RDM1-1", "name": "Sal-like protein 4", "aln": "---------MSRRKQAKPQHINSEEGQGEQPLQQPSPGLAEAP----AAEEPGVPVNSSGNGDEASEDPAPAPVKRSRREDTHICNKCCAEFFSLSEFMEHKKSCTKNPPVLIMNDSEGAVP-----------PEDFSRAVL----GSPSNKDGLQENGGSSSGDLKENLGTDSILYLKTEATQPPAPQDISYLPKGKVANTNVTLQALRGTKVAVNQRSTDVPAAPVPAAL------SIPWILEQILCLQQQQLQQIQLTEQIRVQVNMWAAHALHSGVAGADTLKALSNHVSQQVSVSQQVSAAVALLSQKASNPTLSLDALKQAKLPHAAVPSTASSLSSGFTPFALK--------------PDGTRVLPNFMSRLPNALLPQ----------------TPGSVLLQSPFSTVTLDQSKKGKGKPQNLSA--SMLDAKTKD--EVVLGKHKCRYCSKVFGTDSSLQIHLRSHTGERPYVCPVCGHRFTTKGNLKVHFHRHPQVKANPQLFATEFQDKGASSTS-----------PHYALPVPIPV----------------------------------------------------DESSLSVDTEP--------------VPVTGTPSIGLPQKLTSGPNPKDLMGGSLPNDIQ------PGPSPESE--------------VGLPLLGAGMMRNPPRAGG--------FQGTGAPESG-----------------------------------------------------------------------------------SETLKLQQLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNMAVKTQHSCPICQKKFTNAVMLQQHIRMHMG-----------------------------------------------GQIPNTPLPESPCDFTVPEPMAVSENGGGSGVCQEDAVEG-MEAEEACIQDVP--------------GGPSTVSAPLPGTHLASPS--------LGFPVMAPLDAQGRGALPALAL-----------QRQSSRESGSLEAGDSCLTNDSSSLMGDQ-------------------ECPSRSPDATETMCYQAVSPANSQAGS--------------VKSRSPD-GHKAEGVESCRVDTEGRTSLPSTFIRAQPTFVKVEVPGSFVGPPSVPSGMTP------------LLASQQPPRRQAK-------------------------QHSCTRCGKNFSSASALQIHERTHTGEKPFVCNICARAFTTKGNLKVHYMTHGTNNNSARRGRKLAIENTMAALGAEGKRAPEVFPKELLSPTVSVDPATWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPVSLGASSVVSN---------PTLSKLDGSQTGGSGAMSGAMSGNLEKPGVPDGVAKHQFPHFLEENKIAVS------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BX22-1", "uniprot_id": "SALL4_MOUSE", "id": "Q8BX22-1", "name": "Sal-like protein 4", "aln": "---------MSRRKQAKPQHINWEEGQGEQPQQLPSPDLAEAL----AAEEPGAPVNSPGNCDEASED--SIPVKRPRREDTHICNKCCAEFFSLSEFMEHKKSCTKTPPVLIMNDSEGPVP-----------SEDFSRAALSHQLGSPSNKDSLQENG-SSSGDLKK-LGTDSILYLKTEATQPSTPQDISYLPKGKVANTNVTLQALRGTKVAVNQRGAEAPMAPMPAAQ------GIPWVLEQILCLQQQQLQQIQLTEQIRVQVNMWAAHALHSGVAGADTLKALSSHVSQQVSVSQQVSAAVALLSQKASNPALSLDALKQAKLPHASVPSAASPLSSGLTSFTLK--------------PDGTRVLPNFVSRLPSALLPQ----------------TPGSVLLQSPFSAVTLDQSKKGKGKPQNLSASASVLDVKAKD--EVVLGKHKCRYCPKVFGTDSSLQIHLRSHTGERPYVCPICGHRFTTKGNLKVHLQRHPEVKANPQLLA-EFQDKGAVSAA-----------SHYALPVPVPA----------------------------------------------------DESSLSVDAEP--------------VPVTGTPSLGLPQKLTSGPNSRDLMGGSLPNDMQ------PGPSPESE--------------AGLPLLGVGMIHNPPKAGG--------FQGTGAPESG-----------------------------------------------------------------------------------SETLKLQQLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTTVKTQHSCPICQKKFTNAVMLQQHIRMHMG-----------------------------------------------GQIPNTPLPESPCDFTAPEPVAVSENGSASGVCQDDAAEG-MEAEEVCSQDVP--------------SGPSTVSLPVPSAHLASPS--------LGFSVLASLDTQGKGALPALAL-----------QRQSSRENSSLEGGDTGPANDSSLLVGDQ-------------------ECQSRSPDATETMCYQAVSPANSQAGS--------------VKSRSPE-GHKAEGVESCRVDTEGRTSLPPTFIRAQPTFVKVEVPGTFVGPPSMPSGMPP------------LLASQPQPRRQAK-------------------------QHCCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNNSARRGRKLAIENPMAALSAEGKRAPEVFSKELLSPAVSVDPASWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPVSLGASSVVSN---------GTISKLDGSQTG----VSMPMSGNGEKLAVPDGMAKHQFPHFLEENKIAVS------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJQ4-1", "uniprot_id": "SALL4_HUMAN", "id": "Q9UJQ4-1", "name": "Sal-like protein 4", "aln": "---------MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGAPVNHPGNDEVASED--EATVKRLRREETHVCEKCCAEFFSISEFLEHKKNCTKNPPVLIMNDSEGPVP-----------SEDFSGAVLSHQPTSPGSKDCHRENG-GSSEDMKEKPDAESVVYLKTETALPPTPQDISYLAKGKVANTNVTLQALRGTKVAVNQRSADALPAPVPGAN------SIPWVLEQILCLQQQQLQQIQLTEQIRIQVNMWASHALHSSGAGADTLKTLGSHMS------QQVSAAVALLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLK--------------PDGTRVLPNVMSRLPSALLPQ----------------APGSVLFQSPFSTVALDTSKKGKGKPPNISA----VDVKPKD--EAALYKHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQVKANPQLFA-EFQDKVAAGNG-----------IPYALSVPDPI----------------------------------------------------DEPSLSLDSKP--------------VLVT--TSVGLPQNLSSGTNPKDLTGGSLPGDLQ------PGPSPESE--------------GGPTLPGVGPNYNSPRAGG--------FQGSGTPEPG-----------------------------------------------------------------------------------SETLKLQQLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHIRMHMG-----------------------------------------------GQIPNTPLPENPCDFTGSEPMTVGENGSTGAICHDDVIES-IDVEEVSSQEAP--------------SSSSKVPTPLPSIHSASPT--------LGFAMMASLDAPGKVGPAPFNL-----------QRQGSRENGSVES--DGLTNDSSSLMGDQ-------------------EYQSRSPDILETTSFQALSPANSQAES--------------IKSKSPDAGSKAESSENSRTEMEGRSSLPSTFIRAPPTYVKVEVPGTFVGPSTLSPGMTP------------LLAAQ--PRRQAK-------------------------QHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNNSARRGRKLAIENTMALLGTDGKRVSEIFPKEILAPSVNVDPVVWNQYTSMLNGGLAVKTNEISVIQSGGVPTLPVSLGATSVVNN---------ATVSKMDGSQSG--------ISADVEKPSATDGVPKHQFPHFLEENKIAVS------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKH3-1", "uniprot_id": "Q9VKH3_DROME", "id": "Q9VKH3-1", "name": "", "aln": "---------MCSIFRNRINYRG-----------------------------TGGTRSGSGERERDRDRDRDRDRDRERDRDTLLAKELDADSN--------------------NNGTEPQME-----------AEAVP--------ESDTERETAEERGEEQEPENSNEALDLSLISSGGRESLP--------------GSGHVSLEALQHTKVAVAQFAATAMAG-NHQSA------DLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAEAAALGRHSHSDEEEEEPEPEPEPKKQPTNGLKEELELEQGPESEQDQESRREENSKTDKRGTEDRKAEPE-GYQSMMCD--------------ISSS-LASSIITNHDPPPAPN----------------EPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQS--RGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAPNVGHSGQGQVQGEQYPI-RLPFAPPVAPVG----------------------------------------------------QEQHQNQVEEPEEIRQE--------IPVPQAEDLSKPMVKEKEKSHSPVERVKTPKEVKTDAALPSSEKPEKE--------------ISKPVVTSSRRNGSVRKRQ--------TSAVSPPQEDRERDLVEH--------------------------------LHIAKLVRRSSASRESQPAEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQGAPAANPGEAERLGIEDQNSNKSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATPHPLERERDREKERERRIPNDCSDERSHSNPDLTGGRSESGEMPAMDLSSPSSNSGRIFATGLANGAAGGGSGNGGLPMLGMPMPPNLLLMAAAREEMHALGHAHAKFPLLPFGPLGFMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRPQCSDAGSPYGAKLTLNPNLFAKKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASAGEGSGTGATSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPNSGQGHPGSSAEQEFMQRR---PELFFPYLPPFFNGLPPKPGELSPGAFPNIPPPPFANGGKYPYPPGLLGFPGFLAQHPYILERRSSSKSPTPEPAQSPALREEEGSGNIWHPLSRIKVENNQNESMGGFNEQEDHAETDATGGDNDESESRDAEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39770-1", "uniprot_id": "SALM_DROME", "id": "P39770-1", "name": "Homeotic protein spalt-major", "aln": "MKNHLSNVLCAMRSDFKDNHQETINKMIQFGTVKYGIVKQLKDRARSADKDIGSDQEENGGCSPLTTATTTASPSRSPEPEEEQPEEQSTSEQSIPEQSTPDHQLENDIKSEAKSEIEPVEDNNNRVAMTKPSSEEREPNASGSMPSSPVAEASAEEAATERTPEKEKEKDVEVDVEKPDEAPSSAVPSTEVTLPGG--AGAPVTLEAIQNMQMAIAQFAAKTIANGSNGADNEAAMKQLAFLQQTLFNLQQQQLFQIQLIQQLQSQLALNQAKQEEDTEEDADQEQDQEQETDTYEEEERIADMELRQKAEARMAEAKARQHLINAGVPLRESSGSPAESLKRRREHDHESQPNRRPSLDNTHKADTAQDALAKLKEMENTPLPFGSDLASSIITNHDDLPEPNSLDLLQKRAQEVLDSASQGILANSMADDFAFGEKSGEGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPNHSPAPPPLGSAPASFPPAFPGLQNLYRPPMEILKSLGAAAPHQYFPQELPTDLRKPSPQLDEDEPQVKNEPVEEKDQREEHEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQEDHRIEPRRTPSPSSEHRSPHHHRHSHMGYPPVVQPIQPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSPEHHSPVRSPAGGALPPGVPPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWENFIEVSNTCETMKLKELMK--NKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTG--------------------------------------------EPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHFGALPGGPGGPPGPNHGAHNG----------ALGSESSQGDMDDNMDCGEDYDDDVSSEHLSNSNLEQEGDRSRSGDDFKSLLF---------EQKLRIDATGVVNTNPVRPRSSASSHGHSVG--------------STSAPTSPSVHASSQVIKRSSSPARSEASQG-------------ALDLTPRAAPTSSSSSRSPLPKEKPVSPPSLPRSPSGSSHASANILTSPLPPTVGIDCLP-------------PGLQHHLQQQHQ--------------------------HLMQQQAAVAAAAAAQHHHHQQMAALHQHQEQLRREAAEAQQKAAAAAAAAAAAAAAQRQTPPQARDQRQEGGPGAGPPPNPLMGARPPFGMFPNLPLFPPATTQNMCNAMNQIAQSVMPAAPFNPLALSGVRG-STTCGICYKTFPCHSALEIHYRSHTKERPFKCSICDRGFTTKGNLKQHMLTHKIRDMEQETFRNRAVKYMSEWNEDRE------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: * . * . .* : :: :. . * .* * . .* . : .: : . . . .. *:*:*:: ::*: * .: . : :. : . :: :*:*:* *:** :::: *: : . : : . . . . : :: . : . . : :.. . * *..: : . : .** :.:. . . . . : **:*:** *:**: *:****:********: * :** :********** :**.: . : . : ... :* . :* . * . : : .. ..* . .: . . .*. . .** **::*:. :: :***:*:.*.:*:**:*:*:** *********:*:******:******:*:.:*: . .::. ..**:*::*::*.::******:* . .: . : : .. : . . . .. . . . .. . : :: . .. * * . . :: * *:* . :. . ... . . *. . . * :: * ::::* : * : :. : . :: .* :: : . : : *: : : * . * : ..: . .: . . . * . . . : . * : : *. : ", "identical_positions": 134, "similar_positions": 254, "identity": "8.83%" }, { "cls_id": "homologset.agr.MGI:2139365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N961-1", "uniprot_id": "ABTB2_HUMAN", "id": "Q8N961-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAQQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGASPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPEHCFSSFRR---------------------------------LDARAATEKFNQDLGFRMLNCGRTDLINQAIEALGPDG-VNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSN-SPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEAHGMGSSLHEDMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAE----GVE-ESDASSQGSGSEGPVR--------------LSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLRDFSSIREEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYLYYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-DAFRQLIYGRSSKVQGLDP--LQDLQNTLAERVHS----VYITSRV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQI7-1", "uniprot_id": "ABTB2_MOUSE", "id": "Q7TQI7-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAQQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSPTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRR---------------------------------LDARAATERFNQDLGFRMLNCGRTDLISQAIEALGPDG-VNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSH-SPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEEMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAE----GVE-ESDTSSQGS-SEGPVR--------------LSRTRTKALQEAMYYSAEHGYLDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLKDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-DAFRQLIYGRSSKVQGLDP--LQDLQSTLAERVHS----VYVTSRV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08764-1", "uniprot_id": "ABTB2_RAT", "id": "O08764-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAPQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRR---------------------------------LDARAATERFNQDLGFRMLNCGRTDLISQP-SSPGPDG-VNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSN-SPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAE----GVE-ESDTSSQGS-SEGPVR--------------LSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-MPS-----GSSS------------MAEAAKSRAWT----HCRICRAP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AP57-1", "uniprot_id": "A0A8M3AP57_DANRE", "id": "A0A8M3AP57-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTNSSNMKTLEDLTLD-------------SGYGAGDSCKSLS---------------------------------LSSSKSNS-----------------------------------QAFMN--TPHRG-NWWYYSGS-MNSRNNSWDTVNTVLPEDP--EDIFSKCPR---------------------------------------------------------------------------------LPELEEFPWTEEDVGRVVRKGAG--KGASFSAEAVRRLATLMRRALIRISREAQRLSVMHCRCTKFEVQSAIRLVLSWALADHCVSATVKAISMYNMSAGELLRKGKSARCGLVFSVGRFFRWMVDTRIAVRIHEYAAICLSACMEALVEEVGVRILMAERE--GATPGCVLTAETLEGVINNDAELWGVLQHHEHLICGKNANGVLSLPAHFSPYTEGRQTGLETREDAYAELELRTLEQALLATCVGSISELSDLVSRAMHHMQRLSSVRHGLSPARHARQ--QPVSWSPDALHTLYYFLRCPQMESME-NPNLDPPRMALSKERPFLLLPPLMEWMRVAIVHAEHRRSLLVDSDDVRQTARLLLPGLDCEPRLLKPECCFSSFRR---------------------------------LDAKAATDKFQLDLGFRMLNCGRTDLIGQAIELLGPDG-VNSMDDQGMTPLMYACSAGDEALVQMLIDAGANLDVAVPMC-SPKHPSVHADSRHWVALTFAVLHGHISVAQLLLDAGANVEGAAIRYGQENTSETPLQLASAAGNYEMVSLLLARGADPLLRSQDSNTLTSSLYEDMNCFS---HAAAHGHRNVLRKLLSQPQK-VREDVLSLEEILAE----GVDGETQASGRNGHSLPPPPSPNLSLVSEDALPKLCKTRMKALQEASFYSAEHGYLDVTMELRSLGVPWKLHVWLESLRSAQQKSRAGVMLSLLRDFTSVKEEDYCEELVSVGLPLMFNILKNSKNEAIIQQLGIIFSHCYGTAPLPPIQE---KKAALAAQLDPHFLNNQEMSDVTFLVEGKPFYAHGVLLLTASDRFKTLLAQNGSDSTQTRKDIEISNIKYNIFQMMMSYLYCGGTESLKMGVSELLELLSAASLFQLGVLQRHCEILCAQNIDLDNAVNIYHTAKANGAVELSTYCEGYFLQNMAVLLER-EAFRVMILGSGARSGSGKDSLLEALEATLVRRLRS----LLVTSRV--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F2F4-1", "uniprot_id": "E7F2F4_DANRE", "id": "E7F2F4-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAVSNSTMKTLEDLTLD-------------SGYGAGDSYRSLS---------------------------------LSSSKSNS-----------------------------------QALVS--SPQRG-NWWSYTGS-MNSRNNSWDTVNTVLPEDP--EDIISKCPR---------------------------------------------------------------------------------LPELEEFPWTDEEIDVVLRKVAG--EGLCFAPESVRSVSVLMRRALLRISREAQRLSVVHCRCTRFEVQSAMKLVMSWALAESCVSAAIRAISLYSMSAGEVLRKSKSSRCALSLSVGRFFRWMVDTRISVRVHEYAAICLTACIENLVQEIGLRVLLAAQN---GTNSYPVTAEALEAVVCNDAEIFGLVQNYEHLICGKNANGELSLPAHFSLYAEGPDAAVESRETAYAQLELRTLEQALLATCVGSLSELSDLVSRAMHHMQRLVSTSPGLSPGRPFCL--QPISWSPDALHTLYYYLRSPQMESLE-NPNLEPQRIALNKERPFPLLPPLMEWMRVAMVHAEHRRSLLVDSDDVRQTARLLLPGLDCEPRQLKPECCFTSFKR---------------------------------LDSKAAMDKFNLDLGFRMLNCGRTDLIGQAIQLLGRDG-VNTMDDQGMTPLMYACSAGDEALVHMLIDAGANLDVAVPNC-SPKHPSVHPESRSWVALTFAVLHGHISVVQLLLDVGADVEGRALRNSHHSSAETPLQLASASGNYEMVSLLLSRGADPMLRVH----LTSSLYEGMNCFS---HAAAHGHRNVLRKLLSEPQR-LQEDVLSLEEILAE----GRE-EQEKLEKNGGNMKSVCTS-----------QLCKARIRALQEASLHSAEHGYLDVSMELRALGVSWKLHVWLESIRSAQLHSRTELTLSLLKDFTIIGEEKYCEELLAEGLPFLFSIIKTTKNKDIRKQLAAVFCHCVCSTAAPSILA---VKDTPTAQLDAHFLNNSEMSDVIFVVEGRPFYAHRVLLMSASQRFRDLLSLYQSNGTSDHMAIEITDIKYNTFKMMMAHLYCGGAECLDVSASDLLKLLPVAHSFQLPVLKRHCEILCSERINLNNAVSIYRTAKVSEAVELVVFCEGFILQNMVDLLDC-EAFEELLLDPEVLDG---------LQATLASRLHS----LCGPRRA--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFY3-1", "uniprot_id": "M9PFY3_DROME", "id": "M9PFY3-1", "name": "BTB domain-containing protein", "aln": "MYCTKDCTCSLCRELRGYKPSDKKSAPSAPTLLSRMLNDNFILRRRGISLKNFQPQSLRNSEMLAQQMPVPRPPQTPSPTPIEELPDWATEDSSRAKKPNHKVVIYFGDSIHRGGQQSPLPSPKELHSQLLQEMSQKLKTSVAEEGLTGVEKVKKVQQMAGQPETSPPANDELPPYIESVQNGVINIRIEGNYRRASALVETVAKPTLAVVAPTKSECDCDAALGDNDDGNADDDSDDPGQDEAETDSCDWSYVQEWRRAAKRPTGNLPPNFVQHQAPSQVTGLPPVPPPQMQSPHQVQSQLPPSQTPLSSQKGLAVAMATPAPRVFKELAQQPNKGMPHKMVASSSSCSGGQANSSCKMPSPGTASKALIPQRAVAGPARLTVQSTPVKSQPPQLSGSLSQSQVSPNRPILGIPTTAANPTPPRIHQHDQFRALQRVQECHSSSDENRSSGHASMSDTGGHSSSPAGGMTLGPLPEDRLAAGVTNRSTRSRRHRGIMPGGKAPWSGTGLEDIKLAMLTLRSQTSSSTYSSLSAGSESSEPARRLGRYSSLETVVTSTSADEFVWVDSHNRLVELQHPPWSQQCILKVLRNGRCQQQAEHLAVEAVSRLGYLLQRALVRIAREIQRFSAGVGLCSKQEVVGALRVVLSSSLADSCTKACLRSAAMFAVPGESALKQSKSARAGLQLSVGRFYRWMTDARLGKFIHEYAAVYLCAGIENLLEEIALQCNG-------------TTAAALDQSIASSGDVWGLLQPFAHLNAGRIASGALALPRWANSLDQVIASSGDFR--------------GHLATCVGSIRELKEKALRTQQEFQLAAALSGSALAALFYFMRCSQLEHTELLAASGCHAGQAQSAAPGGGTSSAGHHVQELCYERAYVVLPPLAEWLRVAAAHAEHRNAMMIDKDDVMQAARLLLPGVDCPIRPVAHDEELPTKKTHFNTAPTVSSTGTGTGSSSCSSPVVSGIGIGIGEDTSELGRRATIGVAFKLLLTGRAELLAQAAQLLPPTTRYDTQNSAGLTALMIASIRNDEVALHALLDAGCDPNVEVPPAGSAGYPAIQPDTQHWTALSFAASRANYVALRILLERGGKVEG-GARSSEEKCTLTPLQLAAGTGNLEIVALLLAHGANAFLSTQQKDSLCFAGSAQKGCFCAISVAAAHGHRSCLRKLLTHPVSPGTRDVLSLEEMLAEGDVGGVRGSGGPTGAGGPNSASASGNN-----EDILPLLNKTQIKRLQEAMYHSAENNHLDITIELRKLGVPWTLHCWMHALSAAHDLRLDAVIDQLLQDFLQVCPDDYSAQFVSECLPLLFNIFRN-KNEGTTLLLADIFATCFGWETLPPVKEQPPMQPVQGSRIDPKFVNNPELSDVTFRVEGKIFYGHKIVLVTASPRFQSMLSSKLSEGSSTP-TVQINDIRYHIFQLVMQFLYCGGCSSLDVAHGDVLELMAAASFFQLEGLLRYTEARCSEMVDVDNVVAMYIHAKVYNANRLLEFCQCFLLQNMVALLTYDDSVKRLLFAKKIPNHDVLAGLLQTLQNRLKARKPNSGGGLVNSYRSPPVTPVKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :* * : . . ** *..* : * **.* *:* * . :*. :.: :* : . . **** .: .:..* * **:. **:: : *:*: . :: *:* :. *::***:*::** **:*. *:: ** .*:::* * :**: *. * ::: ::: :.. . *::.**:*..* :*****:***.*:*:. :*****: * * :* *::*: : :* :*: : ...:::*::* . ** .*: *.* *:** . . : * . *******: **.: . *: :.:* . . .. . : : : : :. . . ... * **.: :**** **:*** .:****.: :*..*: *:*******:** * : : :.: : *: : .:.*::* **::*: *. . :: :. *:*.** *. .**. :: *:***.: :: ** *. :*:::.::: *.:*:**. :.: . ::**: *..*** . . .... : ******:.:** *:*:***::**:.:* : : .**. :******. *****:.* *******:*** * . .. . . * ::: : **** :***:.::*:::*** ***.*.** *:.:: :: : **:** : :.* :::: * ::*.*::. **. *. :* * . *.: : . :::*.:*:** *:*** * ***: **.* ::*::** **: ::: .:. . ::*.:::*: *:::* .** ** ..:.: ::*:*:..* *** * *: * *:: :.::..* * ** * .* :*: ::*::* ** . : * . * ", "identical_positions": 286, "similar_positions": 334, "identity": "18.06%" }, { "cls_id": "homologset.agr.MGI:2139369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJZ1-1", "uniprot_id": "RTEL1_RAT", "id": "Q5RJZ1-1", "name": "Regulator of telomere elongation helicase 1", "aln": "MPRVVLNGVTVDFPFQPYPCQQEYMTKVLECLQKKVNGILESPTGTGKTLCLLCTTLAWREHLR-DAVSSLKIAERVQG-ELFASRTLSSWRSAADANGDSIDCYTDIPKIIYASRTHSQLTQVIGELRNTSYR-PKVCVLGSREQLCIHPEVKKQESNHMQISLCRKKVASRSCHFYNNVEEKSLEQELATP-ILDIEDLVKNGSKHKVCPYYLSRNLKQQADIIFMPYNYLLDAKSRKAHNIDLKGTVVIFDEAHNVEKICEESASFDLTPRDVASGLEVINQVLEEQARVAQHGELQQEFIIDTSSSGLNMELEDIAKLKMILLHLEEAIDAVQLPGDDRGVTKPGSYIFELFAEAQITFQTKGCILESLDQIIQHLTGRTGVFTNTAG--LQKLMDIIQIVFSVDPLEGSPGSQVGLGSSHFYKVHIHPETSHRRAAQRSDAWS-------TTASRKQGKVLSYWCFSPSHSMRELVQQGVRTLILTSGTLAPLSSFALEMQIPFPVCLENPHIIDKNQLWVGVIPRGPDGVQLSSAYDKRFSEECLSSLGKALGNIARVVPHGLLVFFPSYPVMEKSLEFWQAQGMSKKVEALKPLFVEPRNKGSFSEVIDAYYQQVASPGSNGATFLAVCRGKASEGLDFSDMNGRGVIVTGLPYPPRMDPRVILKMQFLDEMKGRSRVGGQCLSGQEWYQQQASRAVNQAIGRVIRHRHDYGAIFLCDHRFAYADARAHLPSWVRPYLK---VYDNFGRVIRDVAQFFRVAQKAMPLPVP---------QAVTSSVSEGEAAVKEATLSSHSLSTRKAMSLDVHVPSLRRRPVGLPTAGDSE--SSVCVEYEQQTFSAQKRPMGLLAALEYN----EQKAGAS-EEQALSSSTPSLRCEKRLSVEQRGGKKKVRLVNHPEEPVAGTQAGRAKMFMVAVKQALSQANFDTFTQALQHYKSSDDFEALVASLTCLFAEDPKKHTLLKGFYQFVRPHHKQQFEDICFQLTGQRCSYQPGNSLPFGEQAQSTASKQGRRELESKLTLSEGADRQLDPGEHLNQGWPHLSTHLTSKGDTSNCPKVGCVGE---KPGQPAVNDYLSDVHKALGSASCNQLTAALRAYK--QDDDLDKVLAVVAALTTAKPEHLSLLQRFGMFIRRHHKPRFVQTCADLMGLPTIGKGLELPCPRDESTTVPSELTHEDMKPGPSTSKKPEKTQSKISSFLRQRPDQSARSDDT---IMQLPPRLPPEHTTSQWNFVCPACATEDTVLFQCPSCDFCRCRACWQRQLQASRLCPACGAVNRKQSIAQVIWPKPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VGM9-1", "uniprot_id": "RTEL1_MOUSE", "id": "Q0VGM9-1", "name": "Regulator of telomere elongation helicase 1", "aln": "MPRVVLNGVTVDFPFQPYPCQQEYMTKVLECLQKKVNGILESPTGTGKTLCLLCSTLAWQQHLR-DAVSSLKIAERVQG-ELFASRTLSSWGSAAAASGDSIECYTDIPKIIYASRTHSQLTQVIRELRNTAYR-PKVCVLGSREQLCIHPEVKKQESNHMQISLCRKKVASRSCHFYNNVEAKFLEQDLATP-ILDIEDLVKNGSKQKMCPYYLSRNMKQQADIIFMPYNYLLDAKSRKAHSIDLKGTVVIFDEAHNVEKICEESASFDLTPRDVASGLEIINQVLEEQARVTQQGELQQEFIVDTSSSGLNMELEDIAKLKMILLRLEEAIDAVQLPGDDRGVTKPGSYIFELFAEAQITFQTKGCILESLDQIIQHLAGRTGVFTNTAG--LQKLMDIIQIVFSVDPPEGSPGSLVGLGISHSYKVHIHPETSHRRAAKRSDAWS-------TTASRKQGKVLSYWCFSPSQSMRELVCQGVRTLILTSGTLAPLSSFALEMQIPFPVCLENPHIIDKNQLWVGIVPRGPDGVQLSSAYDKRFSEECLSSLGKALSNIARVVPHGLLVFFPSYPVMEKSLEFWQVQGLARKVEALKPLFVEPRNKGSFSEVIDAYYQQVASPASNGATFLAVCRGKASEGLDFSDMNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMRGRSGVGGQCLSGQEWYQQQASRAVNQAIGRVIRHRHDYGAIFLCDHRFAYADARAQLPSWVRPYLK---VYDNFGHVIRDVAQFFRVAQKTMPLPVP---------QAVTSSVSEGEIALKDATLSSYSLSTRKAMSLDVHVPSLRQKPIGLPAAGDSE--SSLCGEYEQQTFSAQQRPMGLLAALEYN----EQKAGAS-EEQALGSSTPSLRCEKRLSTEQKGGRKKVRLVNHPEEPMAGTQAGRAKMFMVAVKQALSQANFDTFTQALQHYKSSDDFEALVASLTCLFAEDPKKHTLLKGFYQFVRPHHKQQFEDICFQLTGQRCGYQPG-----------------KRELESKLTLSEGVDRQLDPGQHLNQGQPHLSAHPTSKGHTSHCTKVGCAVE---KPGQPAVSDYLSDVHKALGSASCNQLTAALRAYK--QDDDLDKVVAVVAALTTAKPEHLPLLQRFGMFVRRHHKPQFLQTCADLMGLPTTGKDLELEGPRDESPTVPPELTHEDLKPGPSMSKKPEKTQSKISSFFRQRPDESVRSDDTTPKPMQLPPRLPHELMKPHR----------------------------------------------SKQ-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ71-1", "uniprot_id": "RTEL1_HUMAN", "id": "Q9NZ71-1", "name": "Regulator of telomere elongation helicase 1", "aln": "MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLR-DGISARKIAERAQG-ELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYR-PKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASP-ILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAG--LQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWS-------TTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVR---VYDNFGHVIRDVAQFFRVAERTMPAPAP---------RATAPSVR-GEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPE--SSLCVEYEQEPVPARQRPRGLLAALEHS----EQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYK--QDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPG--MEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSS-GPPHGPAASEWGL----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C928-1", "uniprot_id": "RTEL1_DANRE", "id": "P0C928-1", "name": "Regulator of telomere elongation helicase 1", "aln": "MPVIKLKGINVDFPFTPYPCQEDYMSKVIECLQKKVNGVLESPTGTGKTLCLLCSTLAWRDHFK-DTISARKITERMGGAELFADRPMSSWG-TAATDGDTPTYYTDIPKIIYASRTHSQLTQVVNELKNTSYR-PKICVLGSREQLCINQEVMRHESNHIKVHMCRAKVSSRSCIFYNNVDEKSTDKEIVNS-ILDVEDLVKTGKKQRVCPYYLSRSLKQHADVIFMPYNYLLDPKSRRAHNIELKGAVVIFDEAHNVEKMCEESTSFDLTPHDLISAIEAVDRLLREQASDISKADSAEDFNVESLNSGLKMDITTIAKVKQILMDLETAINDFEMPANNQGITKPGSFIFELFEMANVNSKTKTETVEAMEQITGYLAGRPGVFLNTSG--LQKVADIIQLVFVAEPAEGSKKSQTGN-SLKEFKVHIHPDNSNFKKKQITDVWA-------SSSTKKQGNVLSYWCFSPGFSMQELLRQEVRCIILTSGTLSPLSSFTCEMQIPFPVSLENPHVIQRDQIFVSIIEKGPDGVQLSTAFDRRFVPENMSSMGNTLVNLSRVVPHGLLVFFPSYPVMDKTLEFWRAKGHADRIENVKPMFVEPRGKGTFTEVIDGYYGKVDDPNSSGGSFFAVCRGKASEGLDFADTYGRGVVITGLPFPPRMDPRVVLKMQYLDEMCRNKISGVKYLTGQEWYRQQASRAVNQAIGRVIRHREDYGAIFLCDHRFKSADARNQLPSWVRPYVK---IYDGFGTMVRDVAQFFRTAQKTRPVPVKKGKAEGHENQADTRLLNTGSSCLTKSVWPSDIY--QKAKTLDAHVPSLKRRKLDSEEHSGREGAARLCIQYEMEMTSKRK-PVSLLDALDDTTDKEEREDTMVGEERASHLSTLSLQHDKRLDDESRGGKRKIKVVQE-RETVTSHTAKTGKAFMMELRRCLSHENFKLIMEALQSYKTADNLNNLLATVAEPLIQDHNTHSLLRGLYQFIRPHHKKEYDERCLELTGEGCGYKQEHSLSREEK-----EALRHNSVKAEIPPVNPPIEQLNSSRLLNQGGSHLGTIQLNGGEVNVRSEEQKPQTS--IKEGPSCSSLLSDIKQAIGAEKTRQMFSALQAYK--TSNNYEQMVSTVVSLLTERDEDIALLERLSVLIRPQHRKQFGELLKSLTGN------------------------------DSAVVQDSDIGSSQQLSYLEERLNARYR---------------PSFHECC--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W484-1", "uniprot_id": "RTEL1_DROME", "id": "Q9W484-1", "name": "Regulator of telomere elongation helicase 1 homolog", "aln": "MPESLIAGIPVHFPFEPYPVQRAYMEKVIHCLRDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQSEHQKQMVKMEKADFSGLGGGAPGGDLSELAKTMG--RANNWGVPKVIYASRTHSQLTQAMRELKRTAYANMRSVVLGSRDQLCIHPEVMREQGNSNKTNMCKLRVHSKTCSFQMRVESRKDHPDLRGPTIMDIEDLVKVGQRLKICPYFASRELVPQADITFMPYNYLLDPKARKANKIELGNTIVILDEAHNIEKICEESASVQIKSSDVAMAIEDVTHIMQVFASGESQ-----DMAGDEPK---DFTLDDLTLLKEMLLELEKAIDAIVVDNAVDGTTFPASMMYELLGKANFTYGNVATIVSLLDKLVQYLLVASQQMSIRKGGTFTLLSDLLTIVFANK--EDVMSKVYASFKVHVLVEESKQGHGKQQGAKQQGGWLGKGTIAAATGLSKVAKIINFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKPLIAELAIPVAQHLENPHIVDQSQVYVKIIGTGPDRQQLISNYANRDNPKYISSLGQTILNVARIVPDGLLVFFPSYPMLNKCVDAWQASGLWADISCKKPIFLEPRSKDQFTSTMEEFYQAIRD--SKGAVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLEANRTRE---NQLLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFKDASQVQQLSKWIRGHLGDRPQCSPFGPIVRELRQFFKNAEANMKLPDE-----------------------RETDSPLETVCKTEDEPLAA-IPKVKREPGSNATFKSAN-------------------------------------ESAIKVEMANSIKTWTPADYASAAGHKLGG-----------------AAPNAMDFMSRLDSNVSSIDFNCCTDSKSGSSG------------------------------LVKIHKRERSSPTAPESSSQ--------------------------VTKKRYKLVENIKVEPSSS------------------QAKEAPEER--------------AAFLRELRSLVTQDQFRRFGKALLEYKNGTYESFQALMAILLDVLSAPKVRYMLVG-MRKYLKNEHKDEFDRRVGNL-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : *: *.*** ** *. ** **:.**:. .**:***********.***::*** : : . *: * . . .. * : * .:**:************.: **:.*:* : *****:****: ** :.:.* : :*: :* *::* * .*: : . :: . *:*:***** *.: ::***: **.: :**: *********.*:*:*:.*:* .::**:*****:**:****:*.::.. *: .:: : :::. : .: :: : . .: : :: :* :*: ** **: . : * * *.* ::**: *:.. . :. :::: :* . : * : : *:: :** . *. . . : . : .: : : . * ::. * .:::.:***.*. .*.:*: ** :*******:*:..: *: **.. *****:::: *::* :: *** ** : : .* : :**:*::: *::*:** ***:******:::* :: *:. . :. **:*:***.*. *:..:. :* : *.*. *:******.******:* **.*::****:** **:*:** ::*: . : *:*****. :*:**************.****::*** ** *. :*..*:* :: . ** ::*:: ***: *: * .: . : .* :*.:::. . . : * * .* : . ** : . ** : :* :* :: . . ::: *:::. . . : :.. . . : .. . .: * : : : :: ** ** :. : ::: : : : *: : :: .*: .* . .* ", "identical_positions": 293, "similar_positions": 313, "identity": "22.3%" }, { "cls_id": "homologset.agr.MGI:2139371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHT3-1", "uniprot_id": "D3ZHT3_RAT", "id": "D3ZHT3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHTRRKS--LPMLSSGPTGRGEPLQMEDSNVEQGAEDVEPG----MPESPGHLTGR-RKNYPLRKRS-LVPEKPKACKVLLTRLENVAGPRS---------------------ADEADELPPDLPKAPSPTPSSEDA------GLVQPRKRRLASLNAEALNNLLLERED-----------------TSSLAGARRSRGGDPHRSRDR--ATGSWS----------------------------------------------------------------------------------------------FSKKRPRLGDLGEGSRDLSPELAPDEGARRDGD----PAPKRLASLNAAAFLKLSQERE---------------------------------------------------LPLRPSRAQAEADGRSTEPLAPKVLR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKVNGKNCPKVRQGAGSGEATGPPNWQEQPEERWPSAPPRGPPIQPSHQAPGKALENPL--RPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLAPLP--------------------MPGNPADYSGPCGGPELTALGGFYLYCGQDGLQCGSYSPCPMLPEGKLSP---VAAP-NEGLLMAPSSVPSG---------------------------------------------------------------------------------------------------------------------------VPFQHPPWSASR-YCSSEDTGANGYSICGVLPLSLTHIGTTCG------------------------------------------GCPYKMPFTAG-CRSLGQLEFPLPEAGHPASPAHPLLGCP-----------------------------------------------------------------------------------------------------------------------------------------------------VPSVPPAAEPIPHLQTPISEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVARACPQSAKPPSGSKS----------------------------------------------------------------GLRTGSSCRHTVRSKAARRPSHPKQPRAQRPR-------------------------------------------------PRRRRRRR------------------------TNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVE-RHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPP-HRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q497V6-1", "uniprot_id": "BAHD1_MOUSE", "id": "Q497V6-1", "name": "Bromo adjacent homology domain-containing 1 protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHTRRKS--LPMLSSGPTGRGEPLQMEDSNMEQGTEDVEPG----MPESPGHLTGR-RKNYPLRKRS-LVPEKPKACKVLLTRLENVAGPRS---------------------ADEADELPPDLPKPPSPTSSSEDA------GLVQPRKRRLASLNAEALNNLLLEREE-----------------TSSLAGARRSRGGDPHRSRDR--ATGSWS----------------------------------------------------------------------------------------------FSKKRPRLGDLGEGSRDLSPELAPDEGARRDGD----PAPKRLASLNAAAFLKLSQERE---------------------------------------------------LPLRPSRAQAEADGRSTEPLAPRILR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKVNGKNCPKARQGAGSGEATGPPNWQEQPDERWPSAPPHGPPTQPSHQAPGKALENPL--RPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLSPLP--------------------MPGNPADYSGPCGGPELTALGSFYLYCGQDGLQCGAYSPCPMLPEGKLSP---VAAP-NEGLLMAPSSVPSG---------------------------------------------------------------------------------------------------------------------------VPFQHPPWSAPR-YCSSEDTGANGYSICGVLPLSLTHIGTTCG------------------------------------------GCPYKMPFTAEGCRSLGQLEFPLPEAGHPASPAHPLLGCP-----------------------------------------------------------------------------------------------------------------------------------------------------VPSVPPAAEPIPHLQTPISEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVARACPQSAKPPSGSKS----------------------------------------------------------------GLRTGSSCRHTVRSKAARRPSHPKQPRAQRPR-------------------------------------------------PRRRRRRR------------------------TNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVE-RHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPP-HRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBE0-1", "uniprot_id": "BAHD1_HUMAN", "id": "Q8TBE0-1", "name": "Bromo adjacent homology domain-containing 1 protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHTRRKS--LPMLSSGLTGRREPLQMEDSNMEQGVEGVEPG----MPESPGHLTGR-RKNYPLRKRP-LVPEKPKACKVLLTRLENVAGPRS---------------------ADEADELPPDLPKPPSPAPSSEDP------GLAQPRKRRLASLNAEALNNLLLERED-----------------TSSLAGTRRSRAGDPHRSRDRDRATGGWS----------------------------------------------------------------------------------------------SSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGD----PAPKRLASLNAAAFLKLSQERE---------------------------------------------------LPLRLPRAHAEVDGRSTEPPAPKAPRP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLP--------------------MPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSP---VAAPHEEGLLLAPSSVPSG---------------------------------------------------------------------------------------------------------------------------TPFQHPPWGSSR-YCSSEDTGVNGYSICGVLPLSVTHAGTTCG------------------------------------------GCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCP-----------------------------------------------------------------------------------------------------------------------------------------------------VPSVPPAAEPVPHLQTPTSEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVARACPQSAKPPSGSKS----------------------------------------------------------------GLRTGSSCRHTARSKAARRPSHPKQPRVQRPR-------------------------------------------------PRRRRRRR------------------------TNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVE-RHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPP-HRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPC4-1", "uniprot_id": "A0A8M9PPC4_DANRE", "id": "A0A8M9PPC4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSITAQVFFLAVVNTASHSSVAASGVSSLTVLQPRYLLVRTFGFAWQSVMTHARQRNSLCGYKSESADQVNCRITMDRTWPEKKAKRCSTQR-GKAKEVKGKSAERDRKLYPLRGRHGLGEVSALNCCVVLTRLDESETCRNGMKAQVKEMQGKSKICKCRKKACKSCKAAEPKSKVKPDKSALYTE------FILEPRQRRLASLNAEAVNSLLLDRVDP--------------QQTSKPSKKQQQTKGDPSLSKDTAKDNDCPR----------------------------------------------------------------------------------------------KSQDNRKRGCTGETEQNRNPKKAKTESDTIDLQTLNSPAPKRLAGLNAAALLKLTSTSS---------------------------------------------------AGKRRGKTEGKPSAGGVRGKQLLSKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKQQHNLACQSTLKVSQQCCSFCEKHALHNEALWDGSTGSHGFISPGYQCR-SMLGFPLKPVKEEKTETDVKSYYCCSQERSVEYCHRLALFLGQKPFPETDEHSLKGFLP----------------SPHTLTHSAMPIGAHPYPCYPGYYVHIAHHGTPSLPVSSNQGSHPPSSVPPLKMCSSGVQRPKLLPSTVSHP---------------------------------------------------------------------------------------------------------------------------TGIPHPAYCNSVGTCYGEACRLSSYAYRPTQPITSRGCSYNAG------------------------------------------CSSCMHKMETEDYSYP----LDDRSSSITMPSALPLSICP-----------------------------------------------------------------------------------------------------------------------------------------------------ISSVPPPTQSVPHLQTPLPDTGR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQVQIRVGRECPQRAKPPSGSRS----------------------------------------------------------------GVRDSAVCPHIKDGQLG-----SGHGSGAAKQ-------------------------------------------------SKISRRRA------------------------TNGWLPVGVATEKEVFIVAEDSASLRRCYEGVQ-RDGEVIRVRDTVLLRSGPRKKSLPYVAKVSAFWDDPESGELMMSLFWYYRPEHTQGGRIPSMHC--ENEIFASRHQDENSVACIEDKCYVLTLAQYCRFCALVKCREEGFPKR-SPLVPPSS-YVIPA-HRCVPNDIDPDLVFVCRHVYDFRYGRLLKNLQ---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWC0-1", "uniprot_id": "Q9VWC0_DROME", "id": "Q9VWC0-1", "name": "", "aln": "MVSKKRSNAAERVQRSTATAAAAAAAAAAAATASSTQGKKRPGKQTKASGGGGDEADDKKSASKTDSAAKKPAKDPTGSSGVSTATTEGGAGNGGGKQTTSTTTSSTSSTTAPSASASASASNSLKLSPEERHEDGKARAINKMLKSLDIKIHGFDNLLPSGEERLNDGVLKSSISENVKTKSRAAAVKVISSLNPGKMPPVKRVRPSPEPVREKVAEKPAEKVLDKEKPKAEQQITPPPAPEESPASKVPKKTVQQAKKAKVESSLVQATVLTTTSAATSAPSSASTSKHTSTKNPGKKSAHSEQMPKKELSKLAKMGKPKKEANLVKSTARLPDSNTESVQMELEEIVSTPTVTPTPSATPTATPTPTATPTLTPTPTATRTRTPTPTLTPTPTPTSTPSSTAIAAGQPAPPPPPPGGAPKQRPKVKYTKTSAGSKGRMQQALNQKAPAASWSGAKDIYDFKSGSEDEEPIKMVLPSLKELREFSDEDNKPLKLFERQAEKTKVQVQDEEEQPLVKKEEKPPSEKEVKVKSKEKEKEKEKDVDPLSNAQQSEPAAKHTTSTSTTSTTSITSVKKQAKRKIATPMPSSAGRKKKTVGKGKAAAAKEPPPSGSSAESSSSEDERKLSAYSGPKRHRMASLNALAKVQCLYENESRTAHELGLSKATQQPPRIRTLDGSDDDNHKDSPRHGDTDRDKGSVSPPHTSAAPPAAPIAPPKEAEPRRELRYVPGGRGVGKHWEFDSDSETEELQLQQTLPPVKKKKLPKKAPPKKVASSETDAKRKKKSVQVEESDDEEAKEKEKEKEKPKPPKQLPKKRKTAFTEELIGDYKGILARKRMASLNASAIVAATYEVERHLDKNLASDCSSFESYDELDTMPTTTSKVTSAAAIKTEVIHIKKEPKESKESLRERERERESERRRERDNELKDSTVGKMSSHSIIEESNDSKYSKETKETNTDTTITTTGYRDSAASTKDAKDCSRPTSSSVVIVQDTDVTITGVYVNASNGAAQEAYCKMQYRVQSSVTEERVLRPGSVEPPKSYTPLSALSSMLPPGASSGLSEAHSSPPLPVHAAPTGPHVLLPGEHLSAGMYHAPDLGLHTEHALPDHHGPPPPSYAAAAAAAAAAAAYHAHQLAPGGGGVLHMHHQHQYAAHAAHAHHYQQAAEYHGGPPPPPHHYGGPPPQGHYGPPPGAPVPVPVAVPNTVTVPPERCDVGSPPPSYRASAYPPPSSVGMPPPTLGGGSSAFCAPSPLHHHQHQHQQPGPGVGPPHHDPSGYYQPAGPLISPHVIAAPPPPAQVKKLQEEDGPVSAAGSPTQLQQQQAAAEAAAAAADQAAAQSQSQSQGQSHGHAHSHAHNPQQAQHPPQPQPYPAGAVAAAAAAAAAHQGVPYSRSMHAAQMHYSTGYPPNYYAPYPGEVMCYSPPTYPPYFSSKVYQPSHPAHPAAHPQGPPPPGAYRRYPYYQHAGPPPPHELYEQQPPPPPVSSGSVSGPAQQQPPTSSPASVGAAGAGTAGAPSGSQLVPAHQQQHQQQHLEHYPGPPSYYAGYSPGGGASAGQCYTRGLQGPYMEYPPQCPCPMPQSCPKNVHTGPHIGSNIISNIDQSSSCSSSMLLSATSNSNIGGGSSSSSSSSSSTTLPACSSATTTTTASALTTSRGPVKNVTPNNSNSSGHTSTNSCRSSNNSNNSSNSSCQTIEMTSWATAATNTTSTTATTATTGTQCQMLVKTELKGENPQVTKMQYEAHVMPPPTPPESYCASDEKLLDDQEQEAELELRLRLGLGLEKSHGGQQHIEAYDLTCSTPPPVTVPQAAAVPRKARIGKSMAREMVYAAQQQLLPEKQLKQPKEAAAKLEAEPEMPFVLKAEIKAETKIKIEHDGEAQASTHISQLPDLKPTIKTEPEQELEQEAASVPSVAKTEPQPEVEVEREQQEPPVDEEQQPTPGGSKQRFNLLALSSGNKKTKTNNSYKSLIKQAEPKSYLCPGRRFIRRHGRAPAKYVKRRQMILTQRQQQRMRLQRREQQQQRRQQREAAAEVVAGAVVTPSLAGNPIEQAGSEVSIVKDQAPNSSATPSASPKRARPRKQEIAALHLLEGLDTTLSRGYFSDPELNHSSRKQAPTAVGGLYAASSPLTTATDHRGKQTTAEKRSKSETKKPPSGESSESGLPCKKPRKEPAGKVKGKGKKTTAGAAATTIASTAETQTEAVNAITASNQETNNNEYQTADLQAQKFRECPAVTDAKVAGTATSTSTASQQQNQQHSDEQHQFLVPSQPATASATAALAATPPPSRQGQATHTKRTRSRCKFGNRKRQRHRPGGVSYELDVTQPPATKANVVPKWNNGWMWAGKAFQGAVFLNSDDPLVLRTCYPAMRHVEGDIIRIRDCVLLKAN-EDNELPYVAKVAHLWQNPEDGEMMMSLLWYYRPEHTDQGR---QRNDCPDEVYASRHRDHNSVACVEDKCYVLTFSEYCRYRRRLRAAEEDVEDVSIVPRRPSIATAPGFPVRTVPEHTNPELVMFCRRAYEFRTRRLLKLPHKNGLVCSSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . . : : : . : : : :. ** . * . :. . . . . : *:::*:***** * . * :. . . . *. * .. ::.. : :: : : * **:*.***:*:: : . * . . : . . : . .: : . . : . * : . . . . :* . * :. . . * : : * . .. : *::* *. . .. . . . * . . .. . : .: ..: * *. .***. ::. *: :. * .: *****. * : * .: . . : : :*: .***: .* * : *:: : :* .* .:. .*: **:** ***::. .... *****:: :*::**.**:****:******* : ** : :*::****:*.*****:*:******:::***: : *.. . ** * **:. :*:**:.**:.*:** *:** : ", "identical_positions": 124, "similar_positions": 182, "identity": "4.9%" }, { "cls_id": "homologset.agr.MGI:2139395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62839-1", "uniprot_id": "GOGA2_RAT", "id": "Q62839-1", "name": "Golgin subfamily A member 2", "aln": "MWPPRFPPPRPGMSEETRQSKLAAAKKKLREYQQKNSPGVP-AGAKKKKKIKNGHSPERTSASDCQSAENVPTDHTAPAPPSTAAATMFLGVVPSPDADLI-----QSHDAGNCSNLMEETKTFSSTESLRQLSQQLNGLVSESTSYINGEG-LTSSNMKELESRYQELAVALDSSYVTNKQLSSTIEELKQQNQDTLDQLEKEKKDYQQKLAKEQGALREQLQVHIQTIGILVSEKAELQTALAHTQQAARQKAGESEDLASRLQSSRQRVGELERTLSTVSTQQKQADRYNKDLTKERDALKLELYKNGKSNEDLRQQNSELEEKLRVLVAEKAAAQLGAEELQKKLEMSELLLQQFSSQSEASGSN------EQLQQAMEERAQLESHVGQLMESLKQLQVERDQYAENLKGESAMWQQRVQQMAEQVHALKEEKEQRESQVQELEASLAELR------SQMEEPPPPEPPTGPSEAEERLQGEVEQLQKELEGLTGQLRAQVQDNESLSHLNREQEGRLLELEREAQHWSEQAEERKQILESMQSDRTTISRALSQNRELKEQLAELQNGFVRLTNENMEITSALQSEQHVKKELARKLGELQERLGELKETVELKSQEAQGLQEQRDQCLSHLQQYAAAYQQHLTAYEQLTSEKEALHKQLLLQTQLMDQLQHEEVQGKMAAEMARQELQEAQERLKASSQENQQLQAQLSLLVLPGE----DMDQEEQDEE-------VPQPSLTIPEDLVSREAMVAFCNAAIARAEEEQARLRVQLREQK-------ARCRSLAHLAAPVQSKLEKEAVVPRDMGDSVSEESNQALHVAMEKLQNRFLEVMQEKVELKERVEELEHCCIQLSGETDTIGEYIALYQNQRAVLKARHLEKEEYISRLAQDKEEMKVKLLELQELVLRLVNERNEWQGKFLAVSQNP---------------------ADVPAPVPTGSQEFGAADQQGDLREVSLADDTEPAQGEAGVP--APQENPTAQQIMQLLREIQNPQERPG--LGSNPCIPFFYRADENDEVKIMVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921M4-1", "uniprot_id": "GOGA2_MOUSE", "id": "Q921M4-1", "name": "Golgin subfamily A member 2", "aln": "MWPPRFPPPRPGMSEETRQSKLAAAKKKLREYQQKNSPGVP-AGAKKKKKIKNGHSPERPTASDCQSPENVPTDHIAPAPPTAATDTMFLGVTPSPDADLT-----QSHDAGNCSNLMEETKTFSSTESLRQLSQQLNGLVSESTSYINGEG-LTSSNMKELENRYQELAVALDSSYVTNKQLSSTIEELKQQNQDTLDQLEKEKKDYQQKLAKEQGSLREQLQVHIQTIGILVSEKAELQTALAHTQQAARQKAGESEDLASRLQSSRQRVGELERTLSTVSTQQKQADRYNKDLTKERDALKLELYKNSKSNEDLRQQNSELEEKLRVLVAEKAAAQLGVEELQKKLEMSELLLQQFSSQSSAAGGN------EQLQHAMEERAQLETHVSQLMESLKQLQVERDQYAENLKGESAMWQQRVQQMAEQVHTLKEEKEHRERQVQELETSLAALR------SQMEEPPPPEPPAGPSEAEEQLQGEVEQLHKELERLTGQLRAQVQDNESLSHLNREQEGRLLELEREAQRWSEQAEERKQILESMQSDRTTISRALSQNRELKEQLAELQNGFVRLTNENMEITSALQSEQHVKKELARKLGELQERLGELKETVELKSQEAQGLQEQRDQCLSHLQQYAAAYQQHLAAYEQLTSEKEAIHKQLLLQTQLMDQLQHEEVQGKMAAELARQELQEAQERLKATSQENQQLQAQLSLLVLPGEG---DVDQEEEDEE-------VPQSSLAIPEDLDSREAMVAFFNAAIARAEEEQARLRVQLKEQK-------ARCRSLSHLAAPVQSKLEKEAVVPRNVDDSASEESNQALHVAMEKLQSRFLEVMQEKVELKERVEELEHCCIQLSGETDTIGEYIALYQNQRAVLKARHLEKEEYISRLAQDKEEMKVKLLELQELVLRLVNERNEWQGKFLAVSQNP---------------------GDVLTPVPTGSQEFGAADQQDDLREVSLADDIEPAQGEAGVP--APHENPTAQQIMQLLREIQNPRERPG--LGSNPCIPFFYRADENDEVKIMVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08379-1", "uniprot_id": "GOGA2_HUMAN", "id": "Q08379-1", "name": "Golgin subfamily A member 2", "aln": "MWPQPRLPPRPAMSEETRQSKLAAAKKKLREYQQRNSPGVP-TGAKKKKKIKNGSNPETTTSGGCHSPEDTPKDNAATLQPS--DDTVLPGGVPSPGASLTSMAASQNHDADNVPNLMDETKTFSSTESLRQLSQQLNGLVCESATCVNGEGPASSANLKDLESRYQQLAVALDSSYVTNKQLNITIEKLKQQNQEITDQLEEEKKECHQK----QGALREQLQVHIQTIGILVSEKAELQTALAHTQHAARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDAN------QQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAELR------NQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQ-------LTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQR-------VRCRRLAHLLASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELEHRCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLLELQELVLRLVGDRNEWHGRFLAAAQNP---------------------ADEPTSGAPAPQELGAANQQGDLCEVSLAGSVEPAQGEAREG--SPRDNPTAQQIMQLLREMQNPRERPG--LGSNPCIPFFYRADENDEVKITVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1IH00-1", "uniprot_id": "GOGA2_DANRE", "id": "A1IH00-1", "name": "Golgin subfamily A member 2", "aln": "------------MADQNRQIKLAAAKKKLKEFQQKTIPSTGSAGPKKKRKVKGD---QTDAPADRRSPENERVDVSQELEEAGAEHVSNPASAINTDNSAPQN---YPADANGDEHPLENNRPLSSTESLRQLSQQLNGLLSESSTHINGDSDPPAVNEKELETRNQELSAALDSSALTNTQLTSKLETLTKQSQELSDQLQKERKEFEQKFTKEQGAMREQLQVHIQTIGILVSEKSELQTALSYTQQAARQKAAEAEDLSSRLQASKQRVSELERTLSSVSTQQKQHERHNKELEKERDSLRLEIIRFNNVSEESRQQSSELSEQLKLRVNENSALKLELEDLRKRLEMADVMLQQFSSQSGPPSEH------QQLQLLLEEKHQLENHATQLMESVAQLQAERDQYAVQMQEDGRVWKDKTEQLLSQVRLMSEERDSTAAQILELQERIMELENTAAVMSTEQEPQASSQLSGPSETELALQETLRSLQEERDALSLQFQAQVRDNEQLSRLVQEQEVKLQELERQAERASEDAQDRLRILEDVQSDKATISRALTQNRELKDQLAELQNGFVKLTNENMELTSALQSEQHVKKEIARKMGQLQEDLHNAKEQLLESSSELTSVQEQRDQYLAHLQQYSAGYQQ-------LLAEREHLQKQFLQQTQLMDRLQHDEVQGKVQLEQSHMQLQEVQEKLSRLVRDNEELKTEVQELLNGSIMNTSHRDEGDGLESQTLP-ESFQKSQIAIPEDFESREEMKEFIHSVLSRVEAERDEMSRRLEEERRIHQDTRQQLTALSHDHHHHHHHEPHSTCAETDGSEGVPVEVHEALRVAMEKLQERFTKLMQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQNQRAIMKQKHVEKEQYINMLAKDKEEMKTKLAELQDLVMRLVGERNEWYSRYMSAVGNRDLLNSNAEQIHPAERRMEISGVDAPAVLDMSTAMDVSSSPQSSTAEIQSQSSERPAADPISSPSLRPQEDGTARQIMQLLQEIQNPQSRPAPFLGENPCIPFFYRPDEHDEVKILVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W289-1", "uniprot_id": "Q9W289_DROME", "id": "Q9W289-1", "name": "", "aln": "---------MPDDTQDAKAQKLAAARKKLKEYQQRASNNNG--------------------------------------------------------------------QPGAEEPVAATTQSHSSTVSISSNLSER----SDSEINVNGGG-------------------AGGTQPPEQSALPTAASYFAQNESEHNGGLADASS--------------------LQAIQVIIAEKAQLNAELTKVRLACRERELELEELRILKDQNQLRLEQLQQHCQDQQSTGEQQR-------QQYAQLQAQLLQSQAQIKDQQSHLNELEAQLKQSNQHQEELQQQLSQKSNELEMAQLKLRQLSDESSVTTDNRVESLVQTQYMYEQQIRDLQAMVGQLTQDKEQAAGQYQNYVQHQSGEIAKLNERNTELSEVLNSLRERERQLVEHVGALERDIQKNIS---LQAQFKEASQVQPSKEETSEQKALKDELAVLKEQIENFEFERHEFQLKIKSQDDQLQLKNSALDELEKQLERLQAEQPDQSKLLATMESDKVAASRALTQNVEMKNQLDELQQRFVQLTNDKAELVIRLDSEEFANREIRQNYNSMEQKLQANEERFKFKDEEMIRLS----------------------------HENVELQRQQLMLQQQLDRLRHYEAK-------AYHAGEETEKENGADAPENEAEEAKEVGLLHNHSHDHSHQHSDGHCHDN-------------------DHDHSHEHNHHNAGDHGHPHDHPHDHTHDHS----------HSHPHDHQHDHPHDHGQNHAHRQAAETLP------TAEAVERLQSRFTTLISQVADLTEEKHSLEHLVLQLQSETETIGEYIALYQTQRRMLKQREYEKAAQMRLLQAEREQLREKIEALNKLVVSLG-------------------------------------------------VELPADAAQAKQPEAAAGSEHTPGEGENSQQ--------IINKIQDIISEIKENTEQPS----HNHAGDHLNCCMGKFEVV----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : *****:***:*:**: . :.. .:. *** *: . .: .:* :** . * .:. :. * . : ::..: . * . . :*:* ::::**::*:: *: .: *.*:: * *:* : .: *: :*:: . .: :: :: *: :: : :: :.. .**. :*: .: : .: :.***::: *:*:*... . : : :: :*: *: :. * : ::*. : . : .:: :: . :. : *.. :: *: : *. . :. : *: *::: : : : : . : . : :: * ***: : : : ::* ::.*:.: ****:** *:*:** ***. **:***:: *:. *:**:..::*: :: ..::: * :* . ...* :. *. ::.* * * :*:*:: *.: : :*.::. :*: .:: : . .. .. .:: . : . : . : .:. .* : . . : *:*:**.** ::.: .:*.*. ..*** :**..**:**********.** ::* :. ** : * ::*::: *: *:.**: * : * . * .. *. . .:* ::: *::: .:*. * . .: : ** ", "identical_positions": 141, "similar_positions": 287, "identity": "13.3%" }, { "cls_id": "homologset.agr.MGI:2139422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIY2-1", "uniprot_id": "DUOX1_RAT", "id": "Q8CIY2-1", "name": "Dual oxidase 1", "aln": "------------------------------------MAVYSAVAWILLFG--VLASLGAQNPVS--WEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLREPYLPNPRHLSNRVMRGPAGQPSLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDRSTGQSPSNPRDLTNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQNSLLMWMAPDPATG-QGGPQGLYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNIAMYEWLPSFLKQTPPEYPGYHPFLDPSISPEFVVASEQFLSTMVPPGVYMRNASCHFQGIANRNSSVSGALRVCNSYWSRENPKLQRAEDVDALLLGMASQIAEREDHLVVEDVQDFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLPPVSHWQDINPALSRSNGTVLEATAALYNQDLSRLELLAGGLLESHGDPGPLFSAIVLDQFVRLRDGDRYWFENNRNGLFSKEEIAEIRNTSLRDILVAVTNVDPSALQPSVFFWLAGDPCPQPSQLSTQGLPACAPLFVRDYFKGSG-FGFGLTIGTLCCFPLVS-----LLSAWIVARLR--MRNFKRLQRQDRQSIMCEKLVGGVEALEWQGR-KEPCRPVLVHLQPGQIRVVDGRLTVLRTIQLRPPQQVNLILSSN---RGRRTLLLKIPKEYDLVLLFNMEEERQALVENIRAALKENGLSFQEWELREQELMRAAVTRQQRGHLLETFFRHLFSQVLDINQADAGTLPLDSSTK-VREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGS-PEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNN-CLSKDQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGVEVPEVIKNLCRRASYISQEKICPSPRMSAHCARNNTKTASSPQRLQCPVDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSRRHQTVQQFKRFIENYRRHIGCVAVFYTITGALFLERAY----YYAFAAHHSGITDTTRVGIILSRGTAAS-----ISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRFIASTAIILTVLHSAGHVVNVYLFSISPLSVLSCLFPDLFHDDGSEFPQKYYWWFFQTVPGLTGVLLLLALAIMYVFASHHFRRRSFRGFWLTHHLYIFLYILLIIHGSFALIQMPRFHIFFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYK--SGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYS------------PPTGDTCARYPKLYLDGPFGEGH-QEWHKFEVSVLVGAGIGVTPFASILKDLVFKSSVS--CQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDSRDLVSVHIYITQ-----LAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSVTHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINK-QDRTHFSHHYENF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AQ92-1", "uniprot_id": "DUOX1_MOUSE", "id": "A2AQ92-1", "name": "Dual oxidase 1", "aln": "------------------------------------MGFHLALAWILLVG--TLASLGAQNSIS--WEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLKEPYLPNPRHLSNRVMRGSAGQPSLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPHGDPVFDPDKRGNVVLPFQRSRWDRNTGQSPSNPRDQSNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPSDSQSSLLMWMAPDPSTG-QGGPRGVYAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPHWGDEELFQHARKRVIATYQNIAMYEWLPSFLKQTPPEYPGYRPFLDPSISPEFVVASEQFLSTMVPSGVYMRNASCHFQGIPSHNSSVSGALRVCNSYWSREHPKLQRAEDVDALLLGMASQIAEREDHVVVEDMQDFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLSPISHWQDINPALSRSNGTVLEATAALYNQDLSRLELLPGGLLESHGDPGPLFSTIVLDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTSLRDILVAVTNVDPSALQPNVFFWLAGDPCPQPSQLSAKGLPACAPLFIRDYFEGSG-FGFGLTIGTLCCFPLVS-----LLSAWIVARLR--KRNFKRLQRQDRQSIMSEKLVGGVEALEWQGR-NEPCRPVLVHLQPGQIRVVDGRLTVLRTIQLRPPQQVNLILSSN---RGRRTLLLKIPKEYDLVLLFNMEEERQALVENVRGALKENGLSFQEWELREQELMRAAVTRQQRGHLLETFFRHLFSQVLDINQADAGTLPLDSSTK-VREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGS-PEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNN-CLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGVEVPEVIKNLCRRASYISQEKICPSPRMSAHCARNNMKTASSPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSRRHQTVQQFKRFIENYRRHIGCVAVFYTITGALFLERAY----YYAFAAHHSGITDTTRVGIILSRGTAAS-----ISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRLIASTAIILTVLHSAGHVVNVYLFSISPLSVLSCLFPGLFHDDGSEFPQKYYWWFFQTVPGLTGVLLLLALAIMYVFASHHFRRRSFRGFWLTHHLYIFLYILLIIHGSFALIQMPRFHIFFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYK--SGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYS------------PPTGDTCARYPKLYLDGPFGEGH-QEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVS--CQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDRQDLVSVHIYITQ-----LAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINR-QDRTHFSHHYENF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRD9-1", "uniprot_id": "DUOX1_HUMAN", "id": "Q9NRD9-1", "name": "Dual oxidase 1", "aln": "------------------------------------MGFCLALAWTLLVG--AWTPLGAQNPIS--WEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATG-QNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSG-FGFGVTIGTLCCFPLVS-----LLSAWIVARLR--MRNFKRLQGQDRQSIVSEKLVGGMEALEWQGH-KEPCRPVLVYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSN---RGRRTLLLKIPKEYDLVLLFNLEEERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQADAGTLPLDSSQK-VREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGS-PEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNN-CLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAY----YYAFAAHHTGITDTTRVGIILSRGTAAS-----ISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYK--SGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYS------------APTGDRCARYPKLYLDGPFGEGH-QEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVS--CQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDHQDLVSVHIYITQ-----LAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINR-QDRTHFSHHYENF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYT3-1", "uniprot_id": "A0AC58IYT3_DANRE", "id": "A0AC58IYT3-1", "name": "NAD(P)H oxidase (H2O2-forming)", "aln": "------------------------------------MGSFELLLRTFLAMFILCQAVGAYSAIT--WEVQRYDGWYNNLADHDRGAADASLVRLYPAQYMDGVYLARQEPHLPNPRRISTTAMSGQSGLLSHKNRSVLSVAFGYHVWSEISESRRAGCPPEFMHIKVQKDDPVFVSNSSQPVLLQFQRADWDTSTGKSPNNPRTQVNHVTAWIDGSSIYGSSSSWSDALREFSGGRLSSSSSRDMPRRSSNGYLMWSSPDPSSGPDSGSQELYEFGNAWANENIFSVTEGIIWFRYHNYLASKLHKEHPSWSDEELFQHARKRVIATFQNIAFYEWLPAFLGTHVTSYPGYQKYVDPGISVEFEAAAVRFGLTLAPPGVYKRNRTCHYRSVVNDDASKSPGLRLCNTFWNRNNPHLQSSLDVDELIMGMASQIAEREDNIIVEDLRDYMYGPLRFSRSDAVALTIQRGRDFGLPSYNQIREALSMAPVNSFEDINPKLKDT--KLLKELADLYENDISRLELFVGGLLETQEGPGPVFSTIILDQFERIRNADRFWFENKQNGLFTEEEIKAIRNTTFHDVLLDVTSAEKGDIQRSVFFWKNGDPCPQPQPIRASDLQPCTKAFSMSYFDDSSKVGFGVTVVVLFLFPVVSSLTVSYIVASAVAQVR--TARFKRFQQKRSGSTKHKEPAHGTTASEWLGHNTAPRQVTLAFSEKKVFQTFDENGSPLSSHSLGNQDHLNVIVSND---HQHRALLLKIPKEYDLVLFFEDGVQRSEFLSLLRSELEGRIQSLTVMEKSEKEMLCDAVTREQRGKIVETFFKHAFSKVLDIDKSDAG----DLSSR-TREALQCELTRAEFASVLGLKSDSLFVESMFTLADKDGNGYLSFQEFLDVIVIFMTGT-SEEKSKLLFSTHDIKGDGFLSKEEFTSLLRSFIDISG--ALSKSQADDGIAAMLQTAGLYNKDRFSWEDFHFLLRDHS-----AQLNIKGMEV-------------LGKKKLGRQHKVSFIRKNS---SSSSVEELTHTPEEEHGQELRQRQTKKAGQSQAKLYVRPQRERFNRNPVQQCVQQFKRFIENYRRHIICTVVIYAISAGLALERCISMFVDYGLQAHSSGIPETSMVGVLVSRGSAAA-----ISFLFPYMLLTVCRNLITMCRETFLNRYIPFDAAIDLHRQMAATALILSVVHSLGHLVNVYIFCISDLSILACLFPKVFSNNGSELPMKWTFWFFKTVPGITGVILLLIFAFMYVFASHYFRRISFRGFWITHHLYVLIYVLTVVHGSYGLLQQPRFHIYLIPPGLLFLLDKLISLSRKKVEIPVLKAELLPSDVTMLEFKRPQGFVYR--SGQWVRIACLTLGTDEYHPFTLTSAPHEETLSLHIRAAGPWTSKLREAYS------------PEKHQELGGLPKLYLDGPFGEGH-QEWTDFEVSVLVGAGIGVTPFASILKDLVFKSSVK--FKFHCKKVYFLWVTRTQRQFEWLSDIIREVEDMDMQDLVSVHIYITQ-----LPEKFDLRTTMLYVCERHFQKVWNRSLFTGLRSVTHFGRPPFLAFLSSLQEVHPEVEKVGVFSCGPPGLTKNVEKACQQMNK-RDQTHFVHHYENF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQH2-1", "uniprot_id": "DUOX_DROME", "id": "Q9VQH2-1", "name": "Dual oxidase", "aln": "MSVPSAPHQRAESKNRVPRPGQKNRKLPKLRLHWPGATYGGALLLLLISYGLELGSVHCYEKMYSQTEKQRYDGWYNNLAHPDWGSVDSHLVRKAPPSYSDGVYAMAG-ANRPSTRRLSRLFMRGKDGLGSKFNRTALLAFFGQLVANEIVMASESGCPIEMHRIEIEKCDEMYDRECRGDKYIPFHRAAYDRDTGQSPNAPREQINQMTAWIDGSFIYSTSEAWLNAMRSFHNGTLLTEKDGKLPVRNTMRVPLFNNPVPSVMKMLSPERLFLLGDPRTNQNPAILSFAILFLRWHNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFLGTSLPPYEGYKQDIHPGIGHIFQAAAFRFGHTMIPPGIYRRDGQCNFKETPMG----YPAVRLCSTWWD--SSGFFADTSVEEVLMGLASQISEREDPVLCSDVRDKLFGPMEFTRRDLGALNIMRGRDNGLPDYNTARESYGLKRHKTWTDINPPLFETQPELLDMLKEAYDNKLDDVDVYVGGMLESYGQPGEFFTAVIKEQFQRLRDADRFWFENERNGIFTPEEIAELRKITLWDIIVNSTDVKEEEIQKDVFMWRTGDPCPQPMQLNATELEPCTYLEGYDYFSGSE-LMFIYVCVFLGFVPILCAG-----AGYCVVKLQNSKRRRLKIRQEALRAPQHKGSVDKMLAREWLHA-NHKRLVTVKFGPEAAIYTVDRKGEKLRTFSLKHIDVVSVEESATNHIKKKPYILLRVPSDHDLVLELESYGARRKFVKKLEDFLLLHKKEMTLMEVNRDIMLARAETRERRQKRLEYFFREAYALTFGLRPGERRRRSDASSDGEVMTVMRTSLSKAEFAAALGMKPNDMFVRKMFNIVDKDQDGRISFQEFLETVVLFSRGK-TDDKLRIIFDMCDNDRNGVIDKGELSEMMRSLVEIARTTSLGDDQVTELIDGMFQDVGLEHKNHLTYQDFKLMMKEYKGDFVAIGLDCKGAKQ-------------------------------NFLDTSTNVARMTS------------------------FNIEPMQDKP-RHWLLAKWDAYITFLEENRQNIFYLFLFYVVTIVLFVERFI----HYSFMAEHTDLRHIMGVGIAITRGSAAS-----LSFCYSLLLLTMSRNLITKLKEFPIQQYIPLDSHIQFHKIAACTALFFSVLHTVGHIVNFYHVSTQSHENLRCLTREVHF--ASDYKPDITFWLFQTVTGTTGVMLFIIMCIIFVFAHPTIRKKAYNFFWNMHTLYIGLYLLSLIHGLARLTGPPRFWMFFLGPGIVYTLDKIVSLRTKYMALDVIDTDLLPSDVIKIKFYRPPNLKYL--SGQWVRLSCTAFRPHEMHSFTLTSAPHENFLSCHIKAQGPWTWKLRNYFD------------PCNYNPED-QPKIRIEGPFGGGN-QDWYKFEVAVMVGGGIGVTPYASILNDLVFGTSTNRYSGVACKKVYFLWICPSHKHFEWFIDVLRDVEKKDVTNVLEIHIFITQ-----FFHKFDLRTTMLYICENHFQRLSKTSIFTGLKAVNHFGRPDMSSFLKFVQKKHSYVSKIGVFSCGPRPLTKSVMSACDEVNKTRKLPYFIHHFENFG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53109-1", "uniprot_id": "AIM14_YEAST", "id": "P53109-1", "name": "Probable metalloreductase AIM14", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKESPLITLVKRHSETHFANIKYGYYVLIISLVYLIG---------------------LALLRAFGRRTPSRSSSAFKNKIIYRLYDIDPAIHLGILFFAVLIPFYYHYS-LTTQSTVYLKRLGRLSYALIPLNLFLTLR------------------------------------------------------------------------------------------------------------------------------------------------PNWFLRKNCTYTDFIPFHKWFSRIITVIGLLHGIFFIIKWA--------------IDDNVSLKQKLILKTFNF-----AGFIISILVLFLLICSIGPMRRYNYRLFY------IVHNLVNVAFILLTPIHSRPGVKFPFLLLNCTLLFIHIINRIVFAKSLMILNKNANYSKTN----LVHVRLPRAILPDYFEPGSHIRISPYR-----RINPLYWLLPSHPYTIASLAEDNSIDLIIKETSTAEPGSQIESLRSNPKSFHLDQEKTYT--LINSYPPSVPEECYS--QGTNIAIICGGSGISFALPLFRHFFNKEN------------VKYLKMIWL------------IKDYSEYELVLDYLKTNGLTFEK-KLSNNKRISVFISGEYTAETRLDEITTNIDDENSE----------YEMGSFNNEDEDLSISNFNSENADSNDNTPETSHSPTKE-----NGSMIEVKSKHSFTLSNELKSFNN-------------------------ESAQVNQNETWLFSCGPPSLLQLSKKYCN-----DERINFVCETYGL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12209-1", "uniprot_id": "FRE8_YEAST", "id": "Q12209-1", "name": "Probable ferric reductase transmembrane component 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLKSIVSWFKEHLPSFDVDVDKHFRTLRVRKYSQICLLISFIIICVIIPLMN--------------------YLLLTDKFFKICHHLKHHVFNRRSWVHKTHMYHKQSLQLCLICFVFTSFFVIQGANGDLLEITKRMGRISVALMPPLLFLTLR--------------------------------------------------------------------------------------------------------------------------------------------------PSPLPHTLYLALLPLHKWISRIVVLESILHTWFYLYYMYINDTLYVKMRKLPNIYGVIALGLFLLIAITSVRYARRWSYRVFYYVHYVSTWLILVFLHYHARPGISYYTTLNVLILTGQIVYRLHITNVTRVTIVPISSSLSLLEFPLTDLPKKPILPGGHLRINIYHRNFLRRFFSHLIPFQHPFTIASIPSDNLVRLIIRNGHFPLRTNEKYYITGAFEPELSFISKPTVPFNITTKSSKNPFRNNSSALINSPLNFLIKAQRVFMCVGGSGISFGLPLLRILNFNGVNVRLLWVS-RDYKDLEVLNHFKNNFEGMEIYISGTEGNEQDIEIDYIDYHDCAADINDEVRSISSSGRVSELGDNSMLSDGNPQPTEPNENTALLSKKSTLRNHHPPKTSDIPDINAD--DEIDFTYAFSRSKSRKNTAQGTLTTHSSFNGSSVFRQPKIIEPPAQDPCLEAAPKKIRIPAGVKVFFGRPTLGDKDYEWCLQTECDAETDSIQCCRWANQGRDHAEYLSQVWVLAAGPRGLIESTKRWAT-----DGGLHFHGESFAL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : * . : . . : : : . : . . ..: : : : :: : : : : : : : : .: : : * . . . : : . : : : . . .* . : : .. .: :* . : : .* : : . : : :. : . . . : : : . :.::. . : . . : .. : . . : : : : . . .. : :::.** : : . * . : ", "identical_positions": 8, "similar_positions": 108, "identity": "0.49%" }, { "cls_id": "homologset.agr.MGI:2139434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20689-1", "uniprot_id": "MYLK2_RAT", "id": "P20689-1", "name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "aln": "------------------------------------------------------------------------------------------MATENGAVELGTQSLSTDHPPTDAAGDGSPASEKEP-------SLPDTEKDLGPTNTKKDPGAPDPKKNPDPPSLKKTP-EAPGPEK-KGDSAPASASNQGPSGEGDGGGGPAEG----GTGPPAVLPQPTATADASIQKLDATQAPSGNQESGEAKAGKKAAECR--EAGRRGSPAFLHSPSCPAIISCSEKTLAM-------KP-------------LSETTELIFAGVSETPD--PQDPGPAKDEGGTNTLADGKEE---AEAGQAEQAKVQGDTSQRIGFQAVPSERAE-VGQALCLTAKEED-----------------------------------CFQILDDCPPPPAPFPHRIVELRTG-NVSSEFSMNSKEALGGGKFGAVCTCTERSTGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYSAIETSHEIILFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLITKDQSARMSAEQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCR8-1", "uniprot_id": "MYLK2_MOUSE", "id": "Q8VCR8-1", "name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "aln": "------------------------------------------------------------------------------------------MTTENGAVELGSQSLSTEQTPKAAAGDGPSASEKEP-------SAPATEKDLSPPNAKKDPGAPDPKNNPDPPSLKKDPAKAPGPEK-KGDPVPASASSQGPSGEGDGGGGPAEG----SEGPPAALPLPTATAEASIQKLDPTQAPSGNQGSGEAKAGKKAAECR--EAGRRGSPAFLHSPSCPAIISCSEKTLAV-------KP-------------LSETTDLVFTGVSVTPD--PQDPGPVK-AGGTNALAEKKKEEAEKASGQAGQAKVQGDTPQRIGFQAVPSERVE-VGQALCLTAREED-----------------------------------CFQILDDCPPPPAPFPHRIVELRTG-NVNSEFSMNSKEALGGGKFGAVCTCTERATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETSHEIILFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLLTKDQSARMSAEQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1R3-1", "uniprot_id": "MYLK2_HUMAN", "id": "Q9H1R3-1", "name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "aln": "------------------------------------------------------------------------------------------MATENGAVELGIQNPSTDKAPKGPTGERPLAAGK-------------------------DPGPPDPKKAPDPPTLKKDA-KAPASEKGDGTLAQPSTSSQGPKGEGDRGGGPAEG----SAGPPAALPQQTATPETSVKKPKAEQGASGSQDPGKPRVGKKAAEGQ--AAARRGSPAFLHSPSCPAIISSSEKLLAK-------KP-------------PSEASELTFEGVPMTHS--PTDPRPAKAEEGKNILAESQKEVGEKTPGQAGQAKMQGDTSRGIEFQAVPSEKSE-VGQALCLTAREED-----------------------------------CFQILDDCPPPPAPFPHRMVELRTG-NVSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9N0-1", "uniprot_id": "A0AB13A9N0_DANRE", "id": "A0AB13A9N0-1", "name": "", "aln": "MSLKDSMKCPVPPSNPTTLEAKVDDLRLKVELLLGSSRSCSMCGTCAQHRALQETLTSQLSTQTRLLDSLEKKVMEMRVALEDLTRGLEDRQCERVSVPLVALQRRKSLPVRSSAEEVYICLDRDRKTMPHAFNKPSEKGILLEVNENNGTRREDHQAKKDSTEVKVEPTLPIKRENGTSSVTPRSEQTQKMNKTENKSMPPTQNHVLIPIRTPAIASQKTEAQEIRKVPPPNIKVPVAAAVIIPNTTGQTCTESVNVTPANHILPKTTVTPAAPPLVNNNTPKLTVSEVPKDFKPSHKYPQTSLPPSVAAQRSEQTPVNMPTTKTTTPQDAALFPPTHKPPKTVGLSVTTATKEASSLRQVHSCPNSLQRLQVPGLKADLVHTVTSTLTSKKRATETVGAAKLTSDGIQIKISSATDKNSAQTKSYNPPKLCFKVIDDVSPQPAPFAHRFVALKSSPPPCDTFSIHTREVLGGGRFGKVHKCTETRTGMRLAAKIINTRNSKERDMALNEMQVMNQLSHPNILQLYEAFEVKNQVVLILEYVEGGELFERIVDESSPLTEVDAMVFVKQICEGVQYMHQMYVLHLDLKPENILLVNRSSHQVKIIDFGLARRYKPREKLKVSFGTPEFLAPEVVNFDFVSFPTDMWTLGVVTYMLLSGLSPFLGDDDGQTLNNVLMGNWYFDEDAFEHVSADARDFVSNLLIRERSGRMSATQCLKHPWLNNIFEKAKSSNIVLKSQVLLKKYMARRLWKKNYIAIAAANRFKKIGSSGSLTSLGI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :* * . .. . .: : . : .. * : *.. :* . . *: . . * ..* . : . *::. .** . * : : : . . .*:..:* ...: * :*:.*.::. . *: ** :: :: .:. * * *. . . ... *.: :: : : . .: :: . * .:* . : : **:::** .* ****.**:* *::. . **::::*.****:** * .* * **::****:*:.:..*:::*.* *::*****.* *::*** *:*. ::::*::**:************. *****:****:***:*: :**:* ************ ** :.* ************:*.*****.*******:*****:* :* ****::**:**************** :****** .******::** ** :*:******: ::: .**.* *** ******: **** .* ****:*****: :* ****:**::********.***:* :**:", "identical_positions": 245, "similar_positions": 170, "identity": "31.53%" }, { "cls_id": "homologset.agr.MGI:2139444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1T4-1", "uniprot_id": "D4A1T4_RAT", "id": "D4A1T4-1", "name": "", "aln": "MMSSTYCGNSSAKMSVHEVSESSLSLEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWEDEVEEFDKGTFEYALA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3URE8-1", "uniprot_id": "CTXN2_MOUSE", "id": "Q3URE8-1", "name": "Cortexin-2", "aln": "-MSSTYCGNSSAKMSVHEVSESSLSLEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWEDEVEEFDKGTFEYALA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C2S0-1", "uniprot_id": "CTXN2_HUMAN", "id": "P0C2S0-1", "name": "Cortexin-2", "aln": "-MSSTYCGNSSAKMSVNEVSAFSLTLEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWEDEVEEFDKGTFEYALA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***************:*** **:*********************************************************", "identical_positions": 77, "similar_positions": 2, "identity": "93.9%" }, { "cls_id": "homologset.agr.MGI:2139447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UE39-1", "uniprot_id": "GLT13_RAT", "id": "Q6UE39-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 13", "aln": "---------MR---RLVYCKVVLATSLMWVLVDVFLLLYFSECN-------KCDDKKERSLLPALRAVISR--------------------------------------------------NQEG---PGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDLCLDVSRLSGPVIMLKCHHMRGNQLWEYDAERL----------TLRHANSNQCLDEPSEED-KMVPTMQDCSGSRSQQWLLRNMTLGT--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF93-1", "uniprot_id": "GLT13_MOUSE", "id": "Q8CF93-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 13", "aln": "---------MR---RFVYCKVVLATSLMWVLVDVFLLLYFSECN-------KCDDKKERSLLPALRAVISR--------------------------------------------------NQEG---PGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDLCLDVSRLSGPVIMLKCHHMRGNQLWEYDAERL----------TLRHANSNQCLDEPSEED-KMVPTMQDCSGSRSQQWLLRNMTLGT--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUC8-1", "uniprot_id": "GLT13_HUMAN", "id": "Q8IUC8-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 13", "aln": "---------MR---RFVYCKVVLATSLMWVLVDVFLLLYFSECN-------KCDDKKERSLLPALRAVISR--------------------------------------------------NQEG---PGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDLCLDVSRLNGPVIMLKCHHMRGNQLWEYDAERL----------TLRHVNSNQCLDEPSEED-KMVPTMQDCSGSRSQQWLLRNMTLGT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BFD9-1", "uniprot_id": "A0A8M2BFD9_DANRE", "id": "A0A8M2BFD9-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "---------MR---RFVYCKVVLTTSLVWVLVDVFLLLYFSECN-------KCDNRKDHSLLPALRAVMSR--------------------------------------------------AHEA---PGEMGKAVVIPKEEQDKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKTYPDDLPNTSIVIVFHNEAWSTLLRTVHSAINRSPRQLLYEILLVDDASERDFLKKKLEDYVATLEVPVRILRMEQRTGLIRARLRGAAATRGQVITFLDAHCECTTGWLEPLMARIKEDRRAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRTYFEEIGTYDSGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVVRVDYGDVSSRKALRESLKCKPFSWYLENVYPDSQIPRRYYSLGEIRNVETNQCVDNMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTDDLCLDASRLNGPVVMLKCHHMKGNQMFEYDAEYVGKWEYDFKKRTFLHIITQSCLTISRLEDGTYGPTVEYCDDSPLQAWTLRNFTRQEVFKKLYYSPTDYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6WV17-1", "uniprot_id": "GALT5_DROME", "id": "Q6WV17-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 5", "aln": "MTFSTFTRKMRGRMRSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGGNQVFAYTKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEK----------WIRHTNTGQCLQRATRDD-ANTPLLRPCSYGKGQQWLMESKFKWQAH------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * *::** ***:**:.*..*: :*:* * ... : .* * * * .. :*. ******.* ** : :: *** ** *****:***:*:*****.*** :**: * *...**.**:*********:****** *.*****: ** *::*********** **:** .* * . ::* *:*:******* ** *:************ ******:*** ::*::***********:****::.** *:************ **.*** **:.*** *:*************: ** ***:** ********************* ***:.*********. :**:****..::: :* *:****:**::**:* :*.*. :.. **** **:**: ****.* *****:**:* :* ** ******.**: *:*.**** *****: ***:******:** ::* :******.* .*** *::**:* *** : **** : * : .** . :* * :. *. . * * :.. ", "identical_positions": 333, "similar_positions": 119, "identity": "51.0%" }, { "cls_id": "homologset.agr.MGI:2139461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXJ9-1", "uniprot_id": "TMM62_MOUSE", "id": "Q8BXJ9-1", "name": "Transmembrane protein 62", "aln": "-----------------------------------------------------------------------------MARMLAVRVVAGLAAAAVAALLLEHYGLAGPT--TPLPKPRGSQRPHPAPGSEANNIFWGLQISDIHLSRFQDPGRALALEKFCSETIDIIQPALVLATGDLTDAKTKEHLGSRQHEVEWQTYQRILKKTRVMEKTKWLDIKGNHDAYNIPSLESIANYYRKYSAVRKDGAFHHIHSTPFGNYSFISVDATQRPGPKRPYNFFGILDEKQMEELVEFSKKSSQSNQTIWFGHFTTSTIMSPSPGIRTVMGSATAYLCGHLHTLGGLMPVLHTRHFTGTLELEVGDWKDNRRYRIFAFDHDLFSFADVTFDKWPVVLITNPKSLLYSCAKHEPLERLFHSTHIRVLAFSLSPITSVTVKIDGGDIGQASHLSGPIFILKWNPRNYSNGTHTIEVFVQDSAGRSRTAHHIFSAQEDAHLTFDPLASFILLTDHYIVARVLFVLIVLIQLTTLITFRYLAYPELKEPLGFANMTTFSLHILSKINISYYSVLLLTLYTVLGPWFVGEIIDGKLGCCFSFGIFVDGHFLQGGLTFINGIIQLVFFNIPLMAYVCWSLLHRCFGHSFRSHLHQG-KYWKIIPVYLLILLLYIWQVYSCYFLHVTYGSLAFTFSPLRTWLTLLTPVLIYRVWTLNSTELGIFMVQLKSHLSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A4E5-1", "uniprot_id": "A0A8I6A4E5_RAT", "id": "A0A8I6A4E5-1", "name": "", "aln": "MVLRSHHGQGCQTLEKPGGVLPPCHPLALLFLVLTTLSNAGEPGCRGAEAWAEARCGGGRRPQRPEVRAGALRCCAAMARMLAVRVAAGLAAAALAALLLEHYGLAGPS--TPLPKPRGSQRPHPAPGSDANNIFWGLQISDIHLSRFQDPGRALALEKFCSETIDIIQPALVLATGDLTDAKTKEHLGSRQHEVEWQTYQRILKKTRVMEKTKWLDIKGNHDVYNIPSLESITNYYRKYSAVRKDGSFHYIHSTPFGNYSFISVDATQRPGPKRPYNFFGILNEKQMEELLSFSKKSSQSNQTIWFGHFTTSTILSPSPGIRTVMGSATAYLCGHLHTLGGLMPVLHTRHFTGTLELEVGDWKDNRRYRIFAFDHDLFSFADVTFDKWPVALITNPKSLLYSCAKHEPLERLFYSTHIRVLAFSLSPITSVTVKIDGGDIGQASHLSGPIFILKWNPRNYSNGTHTIEVFVQDSAGRSTSARHIFSAQENTHLTFDPLASFILLTDHYIVARVLFVLIVLIQLTVLITFRYLAYPELREPLGFANMTTFSLHILSKINISYYSVLLLTLYTVLGPWFVGEIIDGKWGCCFSFGIVVDGHFLQGGLTFISGIIQLVFFNIPLTAYTCWSLLQRCFGHNFRSHLLQG-RYVQIIPVHLLMLLLYTWQVYSCYFLHVTYGSLAFLLSPLRTWLTLLTPVLVYRVWTLNSTELGIFMVQLKSHLSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0P6H9-1", "uniprot_id": "TMM62_HUMAN", "id": "Q0P6H9-1", "name": "Transmembrane protein 62", "aln": "-----------------------------------------------------------------------------MAAVLALRVVAGLAAAALVAMLLEHYGLAGQP--SPLPRPAPPRRPHPAPGPGDSNIFWGLQISDIHLSRFRDPGRAVDLEKFCSETIDIIQPALVLATGDLTDAKTKEQLGSRQHEVEWQTYQGILKKTRVMEKTKWLDIKGNHDAFNIPSLDSIKNYYRKYSAVRRDGSFHYVHSTPFGNYSFICVDATVNPGPKRPYNFFGILDKKKMEELLLLAKESSRSNHTIWFGHFTTSTILSPSPGIRSIMSSAIAYLCGHLHTLGGLMPVLHTRHFQGTLELEVGDWKDNRRYRIFAFDHDLFSFADLIFGKWPVVLITNPKSLLYSCGEHEPLERLLHSTHIRVLAFSLSSITSVTVKIDGVHLGQAVHVSGPIFVLKWNPRNYSSGTHNIEVIVQDSAGRSKSVHHIFSVQENNHLSFDPLASFILRTDHYIMARVLFVLIVLSQLTILIIFRYRGYPELKEPSGFINLTSFSLHVLSKINIFYYSVLLLTLYTVLGPWFFGEIIDGKFGCCFSFGIFVNGHFLQGSITFIIGILQLAFFNIPLMAYMCWSLLQRCFGHNFRSHLHQR-KYLKIMPVHLLMLLLYIWQVYSCYFLYATYGTLAFLFSPLRTWLTLLTPVLIRYVWTLNSTKFGIFMVQLKSHLSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFQ5-1", "uniprot_id": "E7FFQ5_DANRE", "id": "E7FFQ5-1", "name": "", "aln": "-----------------------------------------------------------------------------MLRLFAALVVLGLLLACFTSWLFDSYDGAWHPKRSLFPQSGRSGGP-PHPGGQRDNIFWFVQVSDIHISRFHDPRRIPDFEKFCTDTIDVIKPDLVLATGDLTDAKTESKMGSLQHEVEWQAYHNVLKRSRVLERTKWIDIRGNHDAFNIVSLESVNNYYRKYSANQKVGSFHYVHRTPFGNYSFICADATLVPGPKRPYNFFGIIDESQMDMLETFREESLSSNKSIWFGHYTTSTVISPSPGIRELMSTAVAYLCGHLHTLGGFMPALHSRHQGGTLELELGDWMDNRRYRILAFDHDLFSFSDLTFEDWPAMLITNPKDAQYLQPGVEPLGRIRSSTHIRVLAFSESPITAVYVSVDGVTLGKAVSAGGPLYVLLWDPMHYATGLHTIKVKVEDSAGRSKVREQQFTLEEELTPSFGFVQSFILLTDHYILARIAFVVIVLLNLGGLVLFRFMPVSSTR---GLSSQAWMSLHLVSKSNVFFYTLLLFNLCTALGPWFIGEVIDGHIGVCFAFGVFVDGHFLEGSLTYVVGFIQVLFFNMPLTYYLCWSLHHRCRGTNFRSHFCRPGCRWRTLAVHLGMLVLMIWQAYSCYFLLETYGSLAFFMSPVRTWALLMGLLLVYRAWWGKPLRFSDGSKTNRPL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::* *. ** *...: *:: *. * . : :*:. . * * ** .**** :*:****:***:** * :****::***:*:* *************:.::** *******:*: :**::**:*:***:**:****.:** **:*: ******** :: *:**::* *********..*** ************:::.:*: * : ::* **::*****:****::******* :*.:* ************:**.**:** ******:*** *******:*********:*: * .**. ******. * *** *: ********** *.**:* *.:** :*:* .**:::* *:* :*:.* *.*:* *:****** .: *: :*: :*. : **** *****:**: **:*** :* *: **: .. : *: . : :***::** *: :*::**:.* *.*****.**:***: * **:**:.*:****:*.:*:: *::*: ***:** * **** :** * .****: : : :.*:* :*:* **.****** ***:*** :**:*** *: :*: .* :. .:. :. ", "identical_positions": 335, "similar_positions": 166, "identity": "46.33%" }, { "cls_id": "homologset.agr.MGI:2139469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TMV3-1", "uniprot_id": "FAKD5_MOUSE", "id": "Q7TMV3-1", "name": "Non-canonical pre-mRNAs endonuclease FASTKD5, mitochondrial", "aln": "MSAALKLLEPLKYKAPCNP-AYRAAQSVAHWHMGNITPHGGQTLPECNSSCHLARKVKNVGGTTLPRRTFTASSAHLGLEFNKASTLNASTLHPDSSSAGGG-EEDVEVFDSFEGTRVFLKLRPEYQLHSYNRSDTHQPIAASEVELILHKVTFYQNKLQPEVITNYFYKLSSLPAEQNSVLLSSNSFALLCQLSVKNIQLFNTSDLISILKAFVDLRIPPSLSMLDVYETRFCHQVWEMTLDQLLLVADLWRNLG-RRVPRFFKIFFSYLNLHWRELSLSQLIHLIYIIGENRQVPQDLMQRLESLILKYVDSVNLEEVGTICLGFFKSSSSLS-EFVMRKIGDLACANMQHLSSHTLVHILKMFRFT-HVDHIHFMKQFGEIAPQRIPSLGVQGVMHLTLACSALRILDERVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPN--TEEFYSSLINEIHRKMPEFNQYPEHLLTCLIGLAFSEYFPVEFINVALSPGFVKLAQERSKFELTKELFTLDGTVAIECPDYKGNRLNSHLQQETSANLWNLASKDMRSKPEFLETLYLLETMLGGPQYIKHHMILPHTRSSDLEVQLDANMKPMPFNSEATPTEDGAQLRFKQVGVSLTDDLMNQLLKGKAKRYFQGQIELETGQPPMELRKKTTVPLVNSGCNGTDRLGD-GMVGLCPLAHMQPPLVKLAIQFTNKNQYCYGSRALLGLHNMKRRQLVQIGYRVVELPHWEWLPLLKRTRLEKLAYLHEKVFTSAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAM0-1", "uniprot_id": "A0A8I6AAM0_RAT", "id": "A0A8I6AAM0-1", "name": "", "aln": "MSATLKLLKLLKYKASCNPSAYHAAQSMAYWPMENIAQHGGQNLPKHNSSCHLARKVKNIGDTTLSQRAFTTSSAHLGLEFNKASALKASALHPDSPSARRG-EEDVEVFDSFEGTRVFLKLRPEYQLHSYNRSETRQPLSASEGELILHKVTFYEDKLQPEVITNYFCKLSSLPAEQSSVLLCSNSFALLCHQSVRNIQLFNTSDLVSILKAFVDLRIPFSASMLDVYETRFCHQVWGMNLDQLLLVADLWRNLG-RRVPRFLKIFFSYLNLHWRELSLSQLIHLIYIIGENRQVPQDLMQKLESLILKYIDSVNLEEVGTICLGFFKSSTSLS-EFVMRKIGDLACANMQDVRSHTLVHILKMFRFT-HVDHVNFMRQFGEIAPQRIPSLGVQGVMHLTLACSALRILDERVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPN--TEEFYSSLINEIHRKMPEFNQYPEHLLTCLIGLAFSEYFPAEFINVALSPGFVKLAQMRSKFELTKELFTLDGTVAIECPDYKGNRLNSHLQQEASANLWSLANKDMRSKPEFLETLYLLETMLGGPQYIKHHMILPHTRSSDLEVQLDANMKPLPFNSEATPTEDVAQLRLKQVGVSLTDDLMNQLLKGKAKRYFQGETELETGQLSIELRKKTTVPLVDSDCNGADRLGDTGIAGLCPLTHMQTPLVKLAIQFTNKNQYCYGSRDLLGLHNMKRRQLVQIGYRVVELPHWEWLPLLKRTRLEKLAYLHEKVFTSAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L8L6-1", "uniprot_id": "FAKD5_HUMAN", "id": "Q7L8L6-1", "name": "Non-canonical pre-mRNAs endonuclease FASTKD5, mitochondrial", "aln": "MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVS-STQHGGQDPPEHISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLG-RKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLS-EFVMRKIGDLACANIQHLSSRSLVNIVKMFRFT-HVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPN--AEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2T3-1", "uniprot_id": "Q9W2T3_DROME", "id": "Q9W2T3-1", "name": "RAP domain-containing protein", "aln": "---------------------------------------------------MWARTNYLWRSVGRLRRQVCTTIVSPARIFADRENQFAHGILMDSLKPYAILRPRDSAWQDLPASEGFMRPQPDASAADLYADFLGLVRHCNRMELKISDSRY-------EAFTRCFCEQLHR---------------------LTDEQLLGSLSALAELPVPESPKAKNYMEIWNTLDIECCRRIERWSSEQLLLVSDAWYRLGLVRIGEYVWLALKKLGRKLRKLPPEQLVHSMFLCNLLRRPVFEMFD-FELNLARCVDQMTLSELGVMAMGFFKTQTPIRNPELLTQLYQRLGSELDTVEDIVLVALLKVLRYSSKLPQVEPLKKMLSALESQVDRVSLLTCLHMALLGCELQTCNDALVERILLRFERELETARLKDMERICLVMALFNITTKSGVERRLAERLPDLLRQRIEEILRHPRCFSNCLQFLTMRGVYDLELLGVALEPRFLKHAYPSG--LPGREYFHLDGFARLLGPEYQG-ALVTEKQRQQMGRNYTQYIPDRDGRFKLNNTDRILVEIRDAITMIHRPVTFKHILP-----QYDR--------CDVVLCYDRRQRKALSINGEACQDYSGEILT---RKHLLGERK-----------------------------------------AADDQLVTVVIVIAGWNNVIRDKDRFTGQMDMKLRQLRQLGHQPLVIYWHEWRELEN--SADRQDFLKRRLSQIAKI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. .. :* . :: . . * . . * : .* . . ..::.: . *:: :*: . . .. ** : . :.:. : : : . **:.: . : * . .: :. : . *::: . :*****:* * ** :: .:. : . *. : :.*. .**:* ::: . *: :::: :* : : :* :.*.*:*.:.:****:.: : :: :: : :::: : . ** ::*::*:: :: ::. :::: . .:: :.: :*::* . *: :: ::: : : .: .* **: :* :. :* .. . ..: . * . ::::: *: ::*. : .** *:: : *::..**.* *:: * :* : *** . : *:*:* * :. *:: : * .: :: :* :* : .. ::: : : * . * * :.. : : : :. . :* .::*. : :: *: : : :.:.: ::. *: .. : * :** *** ::*:: : : ** * : :: :*:.:: * ", "identical_positions": 92, "similar_positions": 253, "identity": "11.93%" }, { "cls_id": "homologset.agr.MGI:2139530", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCH5-1", "uniprot_id": "RABEK_MOUSE", "id": "Q8VCH5-1", "name": "Rab9 effector protein with kelch motifs", "aln": "MRGLRQGIMKQLPILE----------PGDKPRK--------------ATWYTLTCPG----------------DRPCPRVGHSCSYFPPVGDAE-----SGKIFIVGGANPNQSFSDVHTMDLGTHQWDTATREGLLPRYEHASFLPSCSPHSIWVFGGADQSGNRNCLQVMSPED-----RTWSTPEVTGSPPSPRTFHTSSAAIGNQLYVFGGG--ERGAQPVEDVKLHVFDANTLTWSQPETHGSPPSPRHGHVMVAAG-----TKLFIHGGLAGDKFFDDLHCIDIGDMS-----WQKLGPTGAVPVGCAAHAAVAVGHHVYMFGGMTATGALNMMYKYHTEKQHWTVLQFDTSLPAGRLDHS-------MCVIPWPVMSTSENKDSDSV-ILTLQDEKGDAAEKAETQSGGPHEESPTTVLLCFVFGG-------------MNTEGEVYDDCLVTVVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8F4-1", "uniprot_id": "RABEK_RAT", "id": "Q4V8F4-1", "name": "Rab9 effector protein with kelch motifs", "aln": "--------MKQLPILE----------PGDKPRK--------------AAWYTLTCPG----------------DKPCPRVGHSCSYFPPVGEAE-----KGKVFIVGGANPNQSFSDVHTMDLGTHRWDTATREGLLPRYEHASFLPSCSPHSIWVFGGADQSGNRNCLQVMNPEA-----RTWSTPEVTGCPPSPRTFHTSSAAIGNHLYVFGGG--ERGAQPVQDVKLHVFDANTLTWAQPETHGSPPSPRHGHAMVAAG-----TKLFIHGGLAGDRFFDDLHCIDIGDMS-----WQKLGPTGTAPVGCAAHAAVAVGHHVYVFGGMTATGALNTMYKYHTEKQHWTILQFDTSLPPGRLDHS-------MCVIPWPVMSASDTEDSGSV-ILSLQDEKGDAAEKPETRSGGSREESPTTLLLCFVFGG-------------MNTEGEIYDDCLVTVVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z6M1-1", "uniprot_id": "RABEK_HUMAN", "id": "Q7Z6M1-1", "name": "Rab9 effector protein with kelch motifs", "aln": "--------MKQLPVLE----------PGDKPRK--------------ATWYTLTVPG----------------DSPCARVGHSCSYLPPVGNAK-----RGKVFIVGGANPNRSFSDVHTMDLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQSGNRNCLQVLNPET-----RTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGG--ERGAQPVQDTKLHVFDANTLTWSQPETLGNPPSPRHGHVMVAAG-----TKLFIHGGLAGDRFYDDLHCIDISDMK-----WQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLLKFDTLLPPGRLDHS-------MCIIPWPVTCASEKEDSNSL-TLNHEAEKEDSADKVMSHSGDSHEESQTATLLCLVFGG-------------MNTEGEIYDDCIVTVVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GQN7-1", "uniprot_id": "RABEK_DANRE", "id": "Q6GQN7-1", "name": "Rab9 effector protein with kelch motifs", "aln": "--------MELIPVLE----------PEQKPQN--------------RHWYVLEPTG----------------AAPGVSVGHTCSFLPAAHHHDEDGGGKGKIVIVGGANPSGSFADSYIINLDTHQWDLPDWEGLQARYEHCSFTPESEPQSLWVFGGAEKSTNRNCVQALRFSDGGEGRRFWQSVQVTGVPPSGRTYHTNSACVGNRLFVFSGG--EAGSSAVTDAQLHVFDAVSVTWTQPDTTGTPPAQRHGHVITAVG-----SDIYIHGGMSGEKFHSDMFTLNTESLK-----WQKVKAKGDLPPGVAAHSSVTFNKNIFIFGGMTADGATNSMFKFQCDKQRWTLLKFEGDLPPGRLDHS-------MCLLPWRVK----MEDS----------------------------EHADVQHLCFVFGG-------------MDTQGVIFNDCLVTVLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38853-1", "uniprot_id": "KEL1_YEAST", "id": "P38853-1", "name": "Kelch repeat-containing protein 1", "aln": "--------MAGFSFAKKFTHKKHGKTPSDASISDQSREASLSTPPNEKFFTKQETPQKGRQFSQGYHSNVNKTSSPPMFARKQVSESRIQPSAV-----PPQQRNVSGPSTTL-HKQLSKQREYTVWNRIKLQNSPFPRYRHVASAYVTDKNQIYVIGGLHDQSVYGDTWILTAFDNATR-FSTTTIDISEATPPPRVGHAAVLCG-NAFVVFGGDTHKVNKEGLMDDDIYLLNINSYKWTVPAPVGPRPLGRYGHKISIIATTQMKTKLYVFGGQFDDTYFNDLAVYDLSSFRRPDSHWEFLKPRTFTPPPITNFTMISYDSKLWVFGGDTLQGLVNDVFMYDPAINDWFIIDTTGEKPPPVQEHATVVYNDLMCVVGGKDEHDAYLNSVYFLNLKSRKWFKLPVFTAGIPQGRSGHSLTLLKNDKILIMGGDKFDYARVEEYDLHTSDIDMQRGTIVYTLDLARIKDLCPGVMDVPTDTPTPRNGNLDLATPVTPTSHQTKNMNVPISAAPLASAPSPAPKDFSDADRLNREVHNRNVSTEHQNQSHPVNSESHLIAEPNILTPYVPSESSQTPVMKITSNKPFDTPTIQKEPDLSETMDPTVGNQRIPSSIYGDNLTPANQIKNNSPILETLPSNEIKTPQNGNIEEIKHLPDADEKIDSTTTFDQEINGDKLGTSSMSKVEEDGNVADEDDEIGVAQMASSPSKDQFKIKHYNESSELSQNNTEIDKLSEPVDITIKKSDTAGHDSANHVIDASDEKNVSPMGDVPTDTKNEEASVPINRDATTEVVDRALFEKLRSELQSLKELTHEKALEAGAHIKELETELWQLKSQKNSGTTKEIDELDSVRLQSKCEILEADNHSLEDKVNELEELVNSKFLDIENLNEVIQFQNEKIKSLELEPNYKEKLEELQIEHENLSRENERLKNESKQHNEDIINNVANYSSQLGSLISHWKENRANSSFLESSSSLISVSDENGEKTVGEPYGDQSRHHRVVINKLTNRLDDLLERSQELTISKEKLSSEYHALKMEHSSLSQDVLVKENEIKKIQNDYKESISSMDSASKALMVSQRELEKYKSLNKKLIDELDELKFKNGVCSENFENGLRSTEESSNNVKNSNSIRENQFNIKINDLKAELFITNQERDDLKSEVLELKKRLLNLENNTKQVNEDADSDLL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P50090-1", "uniprot_id": "KEL2_YEAST", "id": "P50090-1", "name": "Kelch repeat-containing protein 2", "aln": "--------MVPFKLTN--------KVPTDTGPS---------------LISAQSVPR------------------PIVFMDNRNNTRIVTPTLP-----PNQHRGISGASTALPWSPESKNTGKYIWNRVKLKNSPFPRYRHSSSFIVTNDNRIFVTGGLHDQSVYGDVWQIAANADGTS-FTSKRIDIDQNTPPPRVGHASTICG-NAYVVFGGDTHKLNKNGLLDDDLYLFNINSYKWTIPQPIGRRPLGRYGHKISIIASNPMQTKLYLFGGQVDETYFNDLVVFDLSSFRRPNSHWEFLEPVGDLPPPLTNHTMVAYDNKLWVFGGETPKTISNDTYRYDPAQSEWSKVKTTGEKPPPIQEHASVVYKHLMCVLGGKDTHNAYSNDVYFLNLLSLKWYKLPRMKEGIPQERSGHSLTLMKNEKLLIMGGDKTDYASPNIHDLQTSETDQGEGTLLYTLDLSSLNELCPGIMCES--------------------LHAGESFSNSLSGG------------FTPSK-----------STESENQ-----------EIINILTPRLPDS-------KVLSYN---------------DIDEGAG--------------------SYSSALDD--------------KAFERKSDREEKKPQSSKVDSSINKESPGTG------------------------------------------------------------IKVS----------------KKNFPVLRGLTVDSE-EYGSSSYKDTSCQKGIPKNLFDDLNLNLQTLRLEAQQKELETARHISQLEKEVQRLMVIKEASKD---SNFQTARLKN----LEIQKTFLESRINDLKNLLMVKLSQASKLCDQITIQNNGLKTCSEHVTIKRDIIDLENKCDVLKRQNEILVNNMQKITPELHTYLNESSCYLGKLLKSYP------------TSARPPSSEK----------DNQIYEKDSLNKIEKVINEMHETVR----AKEKLHLETQKLNDERDSLRANLLDNNNKLDALRKLSDGSSKSMDLTKKAIHLSQSELEKYRKNNDDLQKEIDRIKTEQAEQDD--------KQEQRGAITHGN--FDAFHRMKINNLKAELYMSKENRDSLKDELLALKKKLYTLEQKK------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : * : . . * : . : :.*... :. .**.* : . ::* ** ... . : :: .*. *. *: . * **.*. : . . : * .::::: : .*: * . * * *:** : . :.:::.** .: :..*: : .: *: : . * : .: :: . ::::*** * : : :. . * :. *. :*: **:: :. :::** :: . :: .: ", "identical_positions": 41, "similar_positions": 105, "identity": "3.47%" }, { "cls_id": "homologset.agr.MGI:2139535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XHX2-1", "uniprot_id": "TPRN_RAT", "id": "Q5XHX2-1", "name": "Taperin", "aln": "-----MAGLGRLDPGPRTVMPAWKREILERRRAKLAALSGGPG--------------------------------------------------------------SGAAPDGPNERLVLAESLGPLSQNPFMRLESERRRGARPA------QQLLELYCRVPGVRTIRADNILIIESAPGFPPAVPP--ASSIRAAEVVVYEEPQPGRVSRLLEKFDSPAAPRRRGSPERFRPALPQLPVAPASAATRAPTNRSLAPAPPVLPSQPAPPISPVPVAQRAGQRSACCEPAHPDGTAGPGARRSDFLQKTGSNSFTVHPRGLPGSAVNRSLSNGPMTQESPAG-------PANGLSGSPPVPGKWKPKVESKEPSLHPPPSPGTPSATPVGPPAFLAPSPASATPSQRQWVSSATSANDSFEIRPSSKPDMETIPIGDLQARALANLRVNSRNSFVLIPKRKAPGNYPSAAGRQFEEPKGEVGWASQSQGLGSQLVSTVDGAPALEKSSLAAEMQWAVREGGCPRPAISDTDKSVRRQRPASPPPFLPAT-TEAEPAEGLGVPG-LTKNGQEPVRPGLPVTFIDEVDSEEAAFQEAKLPSSAVGVPSQYHLHPSTPGHTSELLNRGSNTFTVVPKRKPGTLQEPHLSQTNGQFQ-QGAEEQDADSLSGPHTTLENALKKRYPTVNEIEVIGGYLALQKSCLIKAGSSRKKMKISFNDKSLHTTFEYPSESSLAQEEAEEEEEEEEEEEGEDGEEEEVGPDSEKSFTVLLPRATFVSSVGPESS------SGLSSYTPKHSMAFSKWQEQTLVQAPTEVE-LPPKEVMLTPASQNDLSDFRSEPALYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AI08-1", "uniprot_id": "TPRN_MOUSE", "id": "A2AI08-1", "name": "Taperin", "aln": "-----MAGLGRLDPGPRTVMPAWKREILERRRAKLAALSGGQG--------------------------------------------------------------SGAAPDGPNERLVLAESLGPLSQNPFMRLESERRRGTRPA------QQLLELYCRVPGVRTIRADNILIIESAPGFPPAVPP--AAGIRAAEVVVYEAPQPGRVSRLLEKFDSPAAPCRRGSPERFRPALPQLPVASASAATRTPTNRSLAPASPVRLSQPAPPISPVPVAQRAGQRSACCEPAHPDGTAGPGARRSDFLQKTGSNSFTVHPRGLPRSAVNRSLSNGPMTQESPTG-------PANGLSGSPPVPGKWKPKVESKEPSLHPPPSPGTPSATSVGPPAFPAPSPASATPSQRQWVSSATSANDSFEIRPSSKPDMETIPIGDLQARALANLRVNSRNSFVLIPKRKAPGNYP-LAGRQFEEPKGEVGWASQSQGLGSQLVSTVDGAPALEKSPLAAEMQWAVRKGACPRPAISDTDKCVRWQRPASPPPFLPAT-AEAEPAEGLGVPG-LAKNGQEPVRPGLPVTFIDEVDSEEEAFQEAKLPSSAVGVPSQYHLHPARPGHTSELLNRGSNTFTVVPKRKPGTLQEPHLSQTNGQSQ-QGAEEQDAESLSGPHTTLENTLKKRYPTVHEIEVIGGYLALQKSCLIKAGSSRKKMKISFNDKSLHTTFEYPSESSLAQEEAEEEEEEEGEE---DGEEEEVGPDSEKPFTVFLPRATFVSSVGPESS------SGLSSYTPKHSMAFSKWQEQTLVQTPTDVE-LPPKEVMLTPASQNDLSDFRSEPALYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KMQ1-1", "uniprot_id": "TPRN_HUMAN", "id": "Q4KMQ1-1", "name": "Taperin", "aln": "-----MAALGRPGSGPRAAVPAWKREILERKRAKLAALGGGAG--------------------------------------------------------------PGAAEP---EQRVLAESLGPLRENPFMLLEAERRRGGGAAG-----ARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAP-PGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPP----RPP------PAAPSPPAAPGP----------------------RGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAG-------PANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASP-------PASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPG-LAKNSREYVRPGLPVTFIDEVDSEE-APQAAKLP--YLPHPAR-PLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGP------TLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYTPKHSVAFSKWQEQALEQAPREAE-PPPVEAMLTPASQNDLSDFRSEPALYF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCS9-1", "uniprot_id": "A0A8M2BCS9_DANRE", "id": "A0A8M2BCS9-1", "name": "", "aln": "MSGGDLRVLHQEPGQESPRMPAWKREILERRKAKGGGSGAGAESVASRLNGEVTGSKSKDDVASTSSSRNYSVTAAKRSTKSPDLSPVKTKEHWPSAEPSDLEERTATDNGGAQESLVLQESLGPLQENPFIKLEKERKKRQSQEISSRPVQHILELYGSVPGIRTIRAENIIIIESDPEYFPEGCGLKHSSKLQQNGTVSGYS---SLNDLLDRRGSPVTEIRAKEVVIYDTALSKSEENLSTLVSAPLEGQGRVSRMLQKFDRNYGKLQPRSRSTENLLDLDPTPVRPNSRPKPDVVPKCPVSPQAGCSHSKVFQNIQSSSSNHHTSPSDSGSSTPLSGSPQLVSSARRRFEGTGGRSVTVHPKEDSDRSPSKPVRERDWDSTDGASKAKVPCSPESHRSRADCTSNPMSPPLSPSFEIRPSPRPDLSLLPAGDLQARALANLRLQSRNSFTVIPKSRTAISSP------------------GSTAPSSPVLSPSSPRPLVGVAASEPTVPTPSPASFTP-PPSKLTEKLTVEAKAGSPQHTLPAITPSPVSQPSIDLPVSLDSPLEDPPVDKLPITNIDDI-----------------------VVEPTPPILSPAMQRRKGNTFTVVPKRRP--------EAQSSPSEAPEVVTESPSTPQAPYAHLGTLIKKRYPAAEEIEVIGGYLSLGRSCLTKTGSTGKKLKISFNESSLQSTFEYPAESSEWDSGEDEEEAE------EKGGEDDGGIITGR---IRIPRASYTSSPTHSSN-----STDLSSYTPKHSVEFNAWQEHKLDESTSEDNSQPTEEVMLTPADSSSLSDFSSEPALYF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . :**********::** .. ..* ..: * ** ****** :***: ** **:: ::** * ***:*::**:.::***: * : * : : * . :. **:: ..*.: * . .. . . . . . . :. . ::*.. .*. . .: : ... : . :* . . : *: . :** :* .. :* . . *: .. : : :: . :.. . ******:.:* :. :* *********.** :***** :*** ::. * * .* :. . * : :. . . * .. ::: :..** *** .. . .: :* * . .: **:* **:: :.*: * . : * .*********:* . . . . :... .* :*****:..*********:* :*** *:**: **:*****:.**::*****:*** :. ::: * . *:: . : : :***::.** .*. :.*********: *. ***: * ::. : : *. *.*****....**** *******", "identical_positions": 194, "similar_positions": 195, "identity": "22.96%" }, { "cls_id": "homologset.agr.MGI:2139593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9M3-1", "uniprot_id": "G3V9M3_RAT", "id": "G3V9M3-1", "name": "", "aln": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHVRFLFLKLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLLLENTECHSIYEESPERSDTPVETQQPVSIEPMCQGSGLEKEPANGAQNPVPAKQQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGP-DQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCLGSKNSGSNNSSVTSFSSPPQDSSQRLTHDTSNIHTSTPRNPGSTNHIPFLEESPCGSQNSSEHSVVKPSPGDSSGSLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYP--EKLDTSAHDGPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTG---SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGF6-1", "uniprot_id": "WDR47_MOUSE", "id": "Q8CGF6-1", "name": "WD repeat-containing protein 47", "aln": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQH-------LEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPERSDTPVEAQQPVSSEAMCQGSGLEKEPANGAQNPVPAKQ-EKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQMYQQMLLEGGVNQEDGP-DQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCSGSKNNGSNNSSVTSFSTPPQDSSQRLIHDTANIHTSTPRNPGSTNHIPFHEDSPCGSQNSSEHSVIKPSPGDSSGNLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYP--EKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTG---SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94967-1", "uniprot_id": "WDR47_HUMAN", "id": "O94967-1", "name": "WD repeat-containing protein 47", "aln": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQH-------LEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPER-DTPVDAQRPIGSEILGQSSVSEKEPANGAQNPGPAKQ-EKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGP-DQQQNLTEQFLNRSIQKLGELNIGMDGLGNEVSALNQQCNGSKGNGSNGSSVTSFTTPPQDSSQRLTHDASNIHTSTPRNPGSTNHIPFLEESPCGSQISSEHSVIKPPLGDSPGSLSRSKGEEDDKSKKQFVCINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRVCAYP--DVIDPSAHETPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTG---SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYNG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QV96-1", "uniprot_id": "A0A8M1QV96_DANRE", "id": "A0A8M1QV96-1", "name": "", "aln": "MTAEEIINVKEVEIIKVMLDFLNSRKLHISMLALEKESGVINGLYSDDMLFLRQLILDGQWDEVLQFIQPLECLDKFDRKRFRYIVLKQKFLEALCVNNAMSAEDEPQH-------LELTMQEAVKCLHALEEFCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVQCFEESCGMVAEFIPADRKLSEAGFRASSNRLFQLLIKGVLYECCVEFCQSKATGEEITESEVLLGIDMLCGNGCDDLDLSLLSWLQNLSPSVFSCAFEQKMLNIHVDRLVKPAKAAYADLLTPLISKLSPYPASPLRRPQSADTYMSRSLNPALDGLSYGLSQEKRGVTTDGGKTSPMSHSFANFQH-----MNRSVMMENSGCHSIFEESPESSRTETPSDKMMSSPGP-QNS--RPASAPGQDAPTPGSE-EKNELRDSTDQFQEYYRQRLRVQQHLEQKQQQRELYQQMLREGGVQQHEAPPTAKHNLTEAFLTRSIQRLEELNVGMDDLGEEVQALSQQCKEGTNS---NGEVGDASATPQTQDG--GGGASSVMTSTPQRSASQSGFPPSSQSPVLTKSAQKD---KTGQNDS---LTRSKGPEKEKTKAKFVMVNTLEDTQAVRAVAFHPTGALYAVGSNSKTLRVCAYP--DTLDTSGTGTNKPPVIRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNPETCNATGPDLEFSMHDGTIRDLAFMEGPECGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILSLYTWGGWMIASGSQDKTVRFWDLRVPSCVRVVGTAFQGSG---SPVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQTYKPHSSDVRSVRFSPGAHYLLTGSYDNKVIVTDLQGDLTKQLPLTVVGEHGDKVIQCRWHSHHLSFLSSSADRTVTLWTQAT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1G4-1", "uniprot_id": "Q9W1G4_DROME", "id": "Q9W1G4-1", "name": "Nucleolar protein 10-like N-terminal domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPESRD-------------------------------LDLRKG---DVERPHFEAVTTLSDSQAIRSVDFHPNGKLYAVGSNSKTFRICQYPALSKLRHGHQAAVYPPSVLCKRTKHHRGSIYCTCWSRDGELIATGSNDKTIKYMRFNNDTNQLVGHEMELNMHDGTVRDMCFLDDSSTKSRLLASGGAGDCKIYITDCGTGTPFQAYSGHTGHILSLYSWNNAMFVSGSQDQTIRFWDLRVNVSVNTLDNDRKDGGLESSAVTAVCVDPTGRLLVSGHADSSCTLYDIRGNRPIQRFYPHTAEIRCVRFSPSAYYMLTCSYDNSIRLTDLQGDLAHELSSVVVAEHKDKAITIRWHPTEFSFISTSADKTATLWALPPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * . * ** : : :* :. *.*:**:*:* *** * **********:*:* ** . : . * : **.***:*****..** *:*:******* :* : ** :* : .* ::*:.*****:**:.*::... . :* *.*****:** *** * ::* ********:**:*.. *:.*****:*:******* .*..:.. :. * *.*::*.***:****.:*: **** ******.* :* : **::::*.*****.*:*:** *** .: :*******:::*. **.** **.* ***. .:**:*:***:*.***: ", "identical_positions": 172, "similar_positions": 99, "identity": "18.4%" }, { "cls_id": "homologset.agr.MGI:2139607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYY9-1", "uniprot_id": "D3ZYY9_RAT", "id": "D3ZYY9-1", "name": "ubiquitinyl hydrolase 1", "aln": "MAWVKFLRKPSGNLG-----------KAYPAGSLLSLAPTVGLLNEPGQNSCFLNSAVQVLWQLDIFRRSLRVLTGHICQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDAAECFENILARIHFHLAPNRDADMCTSKSCVTHQKFAMTLYEQCVCRSCGASSDPLPFTEFVRYISTTALCNEVERMMERHERFKPEMFADLLQAANTADDYRKCPSNCGQKIKIRRVLMNCPEIVTIGLVWDSEHSDLTEDVVRSLATHLYLPGLFYRVTDENAVDSELHLVGMICYTSRHYCAFAFHTKSSKWVFFDDALVKEIGTRWKDVVSKCIRCHLQPLLLFYANPDGTAVSTEDALKQVVHWSHYKSVEENMGCEKPII--YKPDNLKENGFGGQIKQKENHKFQGDNISSFNRSQVQTSGRRAPVKLSH-DQREKIKDISRECALKAMEQKNALSSQRKELEKGQRK-DTGRHRDVVDEDLSSFKSASPPASDGFRQQGNPHLYHSQGKGPCKHDRAASESSSSGKVMSSSRSQNPLVPGEKTTGKAKSDSGTGYDTDSSQDSRDKGGSYGSRTKSRHRGWKPMRETLNVDSVFSESEKRQHSPRRKSDIGNRPKCSKDQSCNNWPKANPKRKGLMTIYEDEMKQEAGSRSSHETNG-KGAEKNTGAAESRGPGSSWQMQRTESGYESSDHVSNGSASLDSPGID-GSGAVMDVGGGK---AFSEQIKMNSPNTDSVECVSHQSKDLPEGFRKDLQDLEADDKSYELHPESHVQIKNHLIKRSQIGETNDKLFPSASSQTP----AREYVYQTNEQKGEKPDRTKCSEWRNTEISEGMGLPFHVDESSVAGKRVNSNETVSPSSLSSSVRTAGLKAETGPVIFWPQQNITEQGYSENSLSRELTRQSACNADSCQMPKLHCHRSPPPLPPKKYSTTSVPRLERAGFIPDVRLPEAFNTNFSSLPKHSLSTASGPSSEGSAYMTQEKDKETIQVKHQAANS--CPSSCSTGGFQANSKALVNMFCEPDQDSRSMCPSETVSLTTYFSVDSCMTDTYRLKYHQRP--KLCFPES----------------------------SGHCSDKSLSQTEQVEGSIT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15975-1", "uniprot_id": "UBP53_MOUSE", "id": "P15975-1", "name": "Ubiquitin carboxyl-terminal hydrolase 53", "aln": "MAWVKFLRKPSGNLG-----------KAYQAGSLLSLAPTVGLLNEPGQNSCFLNSAVQVLWQLDIFRRSLRALTGHICQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDAAECFENILARIHFHLVPNRDADMCTSKSCVTHQKFAMTLYEQCVCRSCGASSDPLPFTELVRYISTTALCNEVERMMERHERVKPEMFAELLQAANTADDYRKCPSNCGQKIKIRRVLMNCPEIVTIGLVWDSEHSDLTEDVVRSLATHLYLPGLFYRVTDENATDSELHLVGMICYTSRHYCAFAFHTKSSKWVFFDDAHVKEMGTRWKDVVSKCIRCHLQPLLLFYANPDGTAVSTEDALRQVVHWSHYRSGEENMGCGKPII--YKPDNSKENGFGGQTKQKENHKFQTD-ISSLNRSQMQTSGRRAPVKLSH-DQREKIKDISRECALKAIEQKNALSSQRKDLEKGQRK-DTGRHRDLVDEVLASFKSGSPPASDGFRQQGNPHLYHSQGKGPCKHDRATHESYTSGKVISSSKSQNLLVPGEKTTGKAKSDSGTGYETDSSQDSRDKGGSYSSKTKSRHRGWKPMRETLNVDSVFSESEKRQHSPRRKSDIGSRPRCSKDQSFNNWPKANPKQKGLMTIYEDEMKQEAGSRSSLETNG-KGAEKNLSAAESRGPGTSWQMQRTESGYESSDHVSNGSASLDSPGVE-GSGAVMDVGGGK---AFSEHIKMNSHNMDSMEYISHHCKDHPEGFRKELQDLEADDKIHELHPESHVQIKSHLIKRSQIGETNDKLFPSASPQTL----AREHVYQTNEHKVERPDRSKCSERHNTENSEGTGLPFHVDESSVAGKRVDSNETVSPSSLPSSVRTAGLKPETGPLMFWSQQNITEQGYSDNSLSRELTLLSACNADSCQMPKLHCHRSPPPLPPKKYSTASAPRLERVGLSPDVGVTEAFNTNPSSLPKHSLSPASGPSLEGSPCMTQERDKETIQVKQLAANS--YPSSCSTNSFQ------------PDQDSTSVCPNETISLTTYFSVDSCMTDTYRLKYHQRP--KLYFPES----------------------------SGHHSNNSLSQTEQVEGSIT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70EK8-1", "uniprot_id": "UBP53_HUMAN", "id": "Q70EK8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 53", "aln": "MAWVKFLRKPGGNLG-----------KVYQPGSMLSLAPTKGLLNEPGQNSCFLNSAVQVLWQLDIFRRSLRVLTGHVCQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDAAECFENMLERIHFHIVPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPLPFTEFVRYISTTALCNEVERMLERHERFKPEMFAELLQAANTTDDYRKCPSNCGQKIKIRRVLMNCPEIVTIGLVWDSEHSDLTEAVVRNLATHLYLPGLFYRVTDENAKNSELNLVGMICYTSQHYCAFAFHTKSSKWVFFDDANVKEIGTRWKDVVSKCIRCHFQPLLLFYANPDGTAVSTEDALRQVISWSHYKSVAENMGCEKPVI--HKSDNLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRK-DLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQ-ILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNG-KGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLDSPVID-GNGTVMDISGVKETVCFSDQITTSNLNKERGDCTSLQSQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHLIKRSHVHEDNGKLFPSSSLQIPKDHNAREHIHQSDEQKLEKPNECKFSEWLNIENSERTGLPFHVDN-SASGKRVNSNEPS--SLWSSHLRTVGLKPETAPLIQ--QQNIMDQCYFENSLSTECIIRSASRSDGCQMPKLFCQNLPPPLPPKKYAITSVPQSEKSESTPDVKLTEVFKAT-SHLPKHSLSTASEPSLEVSTHMNDERHKETFQVRECFGNTPNCPSSSSTNDFQANSG-AIDAFCQPELDSISTCPNETVSLTTYFSVDSCMTDTYRLKYHQRP--KLSFPES----------------------------SGFCNN-SLS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIB8-1", "uniprot_id": "A0A8M2BIB8_DANRE", "id": "A0A8M2BIB8-1", "name": "", "aln": "MAWVKLFKKPGGNMSGTGARSGTGLSKSYQPGSMISLALTKGLLNEPGQNSCFLNSAVQVLWQLDIFRRSLRQLSGHFCLGDACIFCALKSIFCQFQQSRERALPSDTLRHALAETFKDEQRFQLGLMDDAAECFENILERIHLHLVSDSATETCTSKSCITHQKFAMTLYEQFVCRSCGASSDPLPFTELVHYVSSTALCQQVERILEKTDRLRSDMFGELLQAANTIGDLRNCPSNCGQSIKIRRVLMNCPEIVTIGFVWDAEQSDLTEDVIRCLGPNLNLSGLFYRVTDENAKKRDLHLVGMICYSSRHYLAFAFHSKSSKWIFFDDATVKEIGSKWKDVASKCIRGHFQPLLLFYANPDGTAVSNEDAPRQTTMWSRYNSPLNGKGTDTQLSGCKKLDSVRDASAGSQRTNQGSHKTPMQSSTSRLKVLPESPSR----------FRESSRDLS----------HRGGGGQRRESDRSYRRSDSFQHKDMTYPRLSSPPENGPRFHCEQRPRTLPSR-VSRTEHSSDHPRVSPQESRSNQGMAS--------------GVSRHADSSSLSHRGSTNPTERGKSKPS--------WRPVREVLNVDSVLSELERRQQQQQRGS-----PRCVRRFAHERGLMKD-KQKGLMTIYEDDSRLETESQSSQESQRQMMVTRSKGGANVAQRSDNWVIQRTESGYESSDRLSSGSTNPDSPGVENFTGKELRLSQDA------QHLRDQGHNNQ--DDSKMEAARSPLYHGKHLAKIQGKNSEHLMKGSPSSRRKLRYSSCGTRKAGNTEKDPSGVDLPP----EQQELSMRWHHSPESPLLRRLGKISSSECNSSDELTNPLSEQEDSAYRSS---------------TSEVAPHESPG-----PNRSSYPWEESAIQSGPSIASHSKHAQRPIEIKTPPFRPRILQEPSQTASRASGRGAPSSSHSGAVHRRMEINGTCPSSSDVSSKSGSDQERGEQVSSEPEG-------------------------------------WDKPSSSVSPGSGVALTTYFSVDNCMTDTYRLKYHHQRPLVLSMPEPRGAGKDGRDAGHSSRMENQSERAKNKPESGNSNNKPTAKWHPVTSKGLDEHGYL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:::**.**:. * * .**::*** * ******************************* *:**.* **********:**.***:***:*****.:******:*********************:* ***:*:... :: ******:************ ****************:*:*:*:****::***::*: :*.:.:**.:******* .* *:*******.*****************:***:*:***** *:* *..:* *.*********** . :*:*******:*:** *****:*****:***** ***:*::****.***** *:****************.*** :*. **:*.* :. * . : * *. :: . *.* .:: .:* : :* : .: **. :*:* :. ..**:: ::. *: * :*:*:. *: . .* : : * *: : . .* *. :. * : ::* * : ..:. . .* :. ::* * * *:*:**.*****::** *:**:. :: . *:. : : .. : *:*********: : * *:** *:: . :. . .: . .* :***********::*.**:. *** :: .* : :. ::: .. * : : . .. . *.* .::. . : :: .. : * : . . * : **. :: : .:. * * : .: . * .. *. :.: . :. * . * : .. .* * . : :.::. * .. : * * . : : .. . : . :: . : .. .:*. * .. * . :..* . : * * .*.. ::********.***********:: * :**. ** .: . : ", "identical_positions": 405, "similar_positions": 278, "identity": "35.4%" }, { "cls_id": "homologset.agr.MGI:2139628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BM88-1", "uniprot_id": "CATO_MOUSE", "id": "Q8BM88-1", "name": "Cathepsin O", "aln": "----MKPQLVNLLLLCCCCLG-----------------RHGVAGTWSWSHQREAAA----LRESLHRHRYLNS-FPHENSTAFYGVNQFSYLFPEEFKALYLGSKYAWAPRYPAEGQRPIPNVSLPLRFDWRDKHVVNPVRNQEMCGGCWAFSVVSAIESARAIQGKSLDYLSVQQVIDCSFNNSGCLGGSPLCALRWLNETQLKLVADSQYPFKAVNGQCRHFPQSQAGVSVKDFSAYNFRGQEDEMARALLSFGPLVVIVDAMSWQDYLGGIIQHHCSSGEANHAVLITGFDRTGNTPYWMVRNSWGSSWGVEGYAHVKMGGNVCGIADSVAAVFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6APT4-1", "uniprot_id": "A0A8I6APT4_RAT", "id": "A0A8I6APT4-1", "name": "Cathepsin O", "aln": "----MKPHAASLLLLCCCCLG-----------------R-GVARTWPWSPQREAAA----LRESLNRHRYLNS-FPHDNSTAFYGVNQFSYLFPEEFKALYLGSKPAWAPRYPAKGQTPIPNVSLPLRFDWRDKHVVNHVRNQKTCGGCWAFSVVSAVESAGAIQGKPLDYLSVQQVIDCSFNNYGCRGGSPLGALSWLNETQLKLVADSQYPFKAENGLCRYFPPSQSGVSVKGFSAYDFSNQEDEMARALLSFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGNTPYWMVRNSWGNSWGVEGYAYVKMGGNVCGIADSVAAVFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43234-1", "uniprot_id": "CATO_HUMAN", "id": "P43234-1", "name": "Cathepsin O", "aln": "MDVRALPWLPWLLWLLCRGGGD-------------ADSRAPFTPTWPRSREREAAA----FRESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TEE1-1", "uniprot_id": "A0A8N7TEE1_DANRE", "id": "A0A8N7TEE1-1", "name": "Cathepsin O", "aln": "----MAHSLTFIVLIIYQELLTGIISVEVIRKSLTEGERLQHSDTFQQDVNNELYQRWINYQSSLQRQAFLNSALGKSNQSAQYGVNQFSYLSQKQFKEQYLTARAEAAPKFDQSKSEIKVKANNPPRFDWRDHGVVGPVHNQGSCGGCWAFSIVEAIESVSAKGGEKLQQLSVQQVIDCSYQNQGCNGGSPVEALYWLTQSKLKLVSEAEYPFKGADGVCQFFPQAHAGVAVRNYSAYDFSGQEEVMMSALVDFGPLVVIVDAISWQDYLGGIIQHHCSSHKANHAVLITGYDTTGEVPYWIVRNSWGTSWGDDGYAYIKIGNDVCGVADSVAAVSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * : *: . :.* :.**:*: :*** : .*.:* **:****** ::** ** :: *:: . :.. * ******: ** *:** ********:* *:**. * *: *: **********::* ** ***.: ** **.: ::*** :::****. :* *:.*. :::*.:::.:***:* .**: * **: **********:**************** :*********:* **..***:******.*** :***::*:*.:***:****::: *", "identical_positions": 154, "similar_positions": 81, "identity": "45.56%" }, { "cls_id": "homologset.agr.MGI:2139667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89000-1", "uniprot_id": "DPYD_RAT", "id": "O89000-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG--VLSRDAPDIESILA----------------------------------------------------------------LNPRIQAHATLRSTMAKKLDKKHWKRNT-----------------------DKNCFICEKLENNFDDIKHTT----------------LGERGALREAVRCLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLHATEEGPINIGGLQQFATEVFKAMNIPQIRSPL-----------------------------------------LPPPEHMPEAYSAKIALFGAGPASISCASFLARLG---------------------------------YSDITIFEKQEYVGG---------------------------LSTSEIPQFRLPYDVVNFEIELMKDLGVK------------------------IICGKSISTDEMTLSTLKEN----------------------------GYKAAFIGIGLP------------EPKKDHIFQGLTQVQGFYTSKDFLPLVAKGSKPGMCACHSP-----LPSVRGAVIVLGAG------DTAFDCATSALR-----CGARRVFIVFRKGFANIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKDGKIVGMQFVRTEQDETGNWVEDEEQIVRLKADVVIS-------------------PFGSVLDDPKVIEALSPIKFNRWGLP------------EVNPETMQTSEPWVFAG---------GDVVGMANTTVESVNDGKQASWYIHEYIQAQYGALVPSQPT----LPLFYTPVDLVDISVEMAGLRFPNPFG--------------LASATPATSTPMIRRAFEAG----------------WGFALTKTFS------LDKDIVTNVSPRIIR--GTTSGPLYGPGQSSFLNIELISE-----------------------------KTAAYWCHSVTELKADFPDNILIASIMCSYNKNDWMELSKMAEASGADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRQSVRVPFFAKLTPNVTDIVS----------IARAAKEGGADGVTATNTVSGLMG-----------------LKADGSPWPSVGS-----------------------GKRTTYGGVSGTTIRPIALRAVTAIARALPGFPILATGG-------------IDSAESGLQFLHSGASVLQVCSAIQNQDFT--------VIEDYCTGLKALLYLKSIEELSD---WDGQS---------------------PPTMSHQKGKPVPHIAELMGQKLPSFGPYLERRKKILAASKIR--ENDQNRACSPLQRKHFNSQKP-IPAIKDVIGKSLQYLGTFGELNIME------------------------------QVVALIDEEMCINCGKCYMTCND--------SGYQAIQFDPETHLPTVSDTCTG------CTLCLSVCP--------------------IMDCIRMVSRATPYEPKRGLPLAVKPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHR6-1", "uniprot_id": "DPYD_MOUSE", "id": "Q8CHR6-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG--VLSRDAPDIESILA----------------------------------------------------------------LNPRVQAHATLRSTAAKKLDKKHWKRNT-----------------------DKNCFTCEKLESNFDDIKHTT----------------LGERGALREAVRCLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLHAAEEGPINIGGLQQFATEVFKAMNIPQIRNPS-----------------------------------------LPPPEHMPEAYSAKIALFGAGPASISCASFLARLG---------------------------------YSNITIFEKQEYVGG---------------------------LSTSEIPQFRLPYDVVNFEIELMKDLGVK------------------------IICGKSLSTDEMTLSSLKEN----------------------------GYRAAFIGIGLP------------EPKKDHIFQGLTQVQGFYTSKDFLPLVAKSSKTGMCACHSP-----LPSIRGAVIVLGAG------DTAFDCATSALR-----CGALRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKDGKIVAMQFVRTEQDETGNWVEDEEQTVRLKADVVIS-------------------AFGSVLEDPKVKEALSPIKFNRWGLP------------EVNPETMQTSEPWVFAG---------GDVVGMANTTVESVNDGKQASWYIHKHIQAQYGTSVPSQPT----MPLFYTPVDLVDISVEMAGLRFPNPFG--------------LASATPATSTPMIRRAFEAG----------------WGFALTKTFS------LDKDIVTNVSPRIIR--GTTSGPLYGPGQSSFLNIELISE-----------------------------KTAAYWCHSVTELKADFPDNILIASIMCSYNKSDWMELSKMAEASGADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRQAVRVPFFAKLTPNVTDIVS----------IARAAKEGGADGVTATNTVSGLMG-----------------LKADGTPWPAVGI-----------------------GRRTTYGGVSGTAIRPIALRAVTAIARALPGFPILATGG-------------IDSAESGLQFLHSGASVLQVCSAIQNQDFT--------VIEDYCTGLKALLYLKSIEELAD---WDGQS---------------------PPIISHQKGKPVPRVAELMGQKLPSFGPYLEQRKKIIAASKIR--QKDQNTACSPLQRKHFNSQKP-IPAIKDVIGKSLQYLGTFGEMSIME------------------------------QVVALIDEEMCINCGKCYMTCND--------SGYQAIQFDPETHLPTVSDTCTG------CTLCLSVCP--------------------IMDCIRMVSRATPYQPKRGLPLAVKPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12882-1", "uniprot_id": "DPYD_HUMAN", "id": "Q12882-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP--VLSKDSADIESILA----------------------------------------------------------------LNPRTQTHATLCSTSAKKLDKKHWKRNP-----------------------DKNCFNCEKLENNFDDIKHTT----------------LGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPS-----------------------------------------LPPPEKMSEAYSAKIALFGAGPASISCASFLARLG---------------------------------YSDITIFEKQEYVGG---------------------------LSTSEIPQFRLPYDVVNFEIELMKDLGVK------------------------IICGKSLSVNEMTLSTLKEK----------------------------GYKAAFIGIGLP------------EPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSP-----LPSIRGVVIVLGAG------DTAFDCATSALR-----CGARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKGGRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVIS-------------------AFGSVLSDPKVKEALSPIKFNRWGLP------------EVDPETMQTSEAWVFAG---------GDVVGLANTTVESVNDGKQASWYIHKYVQSQYGASVSAKPE----LPLFYTPIDLVDISVEMAGLKFINPFG--------------LASATPATSTSMIRRAFEAG----------------WGFALTKTFS------LDKDIVTNVSPRIIR--GTTSGPMYGPGQSSFLNIELISE-----------------------------KTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVS----------IARAAKEGGANGVTATNTVSGLMG-----------------LKSDGTPWPAVGI-----------------------AKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGG-------------IDSAESGLQFLHSGASVLQVCSAIQNQDFT--------VIEDYCTGLKALLYLKSIEELQD---WDGQS---------------------PATVSHQKGKPVPRIAELMDKKLPSFGPYLEQRKKIIAENKIR--LKEQNVAFSPLKRNCFIPKRP-IPTIKDVIGKALQYLGTFGELSNVE------------------------------QVVAMIDEEMCINCGKCYMTCND--------SGYQAIQFDPETHLPTITDTCTG------CTLCLSVCP--------------------IVDCIKMVSRTTPYEPKRGVPLSVNPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYG8-1", "uniprot_id": "DPYD_DANRE", "id": "Q6NYG8-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAT--MLSKELQDIESILA----------------------------------------------------------------LNPRVKSHANVHSTASKKNEKKHWKRNP-----------------------ERSCDSCVNLENNFDDIKHTT----------------LSERGALREALRCLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKAILSDNPLG---------------LTCG--MVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEVFSKMGIPQIRNPE-----------------------------------------LPTADNMPKSFHTRIALIGCGPASISCASFLARLG---------------------------------YDNITIFEKQKYIGG---------------------------LSTSEIPQFRLPYEVVQFEIDLMKDLGVK------------------------VVLEKGLGQNGLTLTSLKEE----------------------------GYQVVYIGIGLP------------QANRDKIFEGLTTEQGFYTSKDFLPLVAKASKIGMCNCRSQ-----LPKLHGNVIVLGAG------DTAFDCATSALR-----CGARRVFVVFRKGFTNIRAVPEEMEAAKEEKCEFLP-----------FLSPHEVIKKNGRVSGLRFCRTEQQDDGTWIVDEEQIVHLKADFIIS-------------------AFGSMLNDPAVTKALDPIKLNRWGTP------------EVNSETMQTTEPWVFAG---------GDIAGFANTTVESVNDGKQASWHIHKYIQSLHGNTISATPR----LPLFHCSIDTVDISVEMCGIKFPNPFG--------------LASAPPTTSAAMIRRAFEQG----------------WGFALTKTFG------LDKDLVTNVSPRIVR--GTTSGHIFGPGQGSFLNIELISE-----------------------------KTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNIVD----------IATAAYEGGADGVTATNTVSGLMA-----------------LKADATPWPGIGR-----------------------GARTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGG-------------IDSAESGLQFLHAGASVLQVCSAVQNQDFT--------VIEDYCLGLKALLYLKSIEELHD---WDGQS---------------------PPTIRHQKGKPVPHVSELIGKSLPSFGPYLQTKTQALAKYKKD--ASG-DVIMDTGAARVNIPKKP-IPNVKDVIARALKHIGAYQELDNTE------------------------------QVQALVDPEMCINCGKCYMTCND--------SGYQAIKFDPETHLPVITDSCTG------CTLCLSVCP--------------------IIDCIKMVSRTTPYEPKRGLP--VNPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W374-1", "uniprot_id": "Q9W374_DROME", "id": "Q9W374-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPPQLLSKDSPDIEDLLS----------------------------------------------------------------LNPRVKTQCSVVPTKQTKENKKHWKRNA-----------------------DHAAPPCTTLANDFSDIKHTT----------------LSERGALEEAARCLKCADAPCQKSCPTQLDIKSFITSIANKNFYGAAKAIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLQASEAGPINIGGLQQFATEVFKKMGVRQRRTP----------------------------------------------QAEANPLSQKIALVGGGPASLSCATFLARLG---------------------------------YRDVTIYERRSYLGG---------------------------LSAAEIPQYRLPIDAVNFEIDLVRDLGVR------------------------IETGRSLGTKDLTIQGLLST----------------------------GHDAVFVGIGLP------------EPKLNPIFAGLQPSNGFYTSKNFLPLVSDGSKPGLCACKAAA---GLPKLHGNVIVLGAG------DTAFDCATSALR-----CGARRVFVVFRKGSSGIRAVPEEVELARDERCELLP-----------YLSPRKVIVKDGLITAMEFCRTEQNENDEWVEDEEQTQRLKANFVIS-------------------AFGSGLEDQDVKAALAPLQF-RGELP------------VVDRVTMQSSVKQVFLG---------GDLAGVANTTVESVNDGKVAAWSIHCQLQGLP---LDTPAA----LPLFYTDIDAVDISVEMCGIRFENPFG--------------LASAPPTTSTAMIRRAFEQG----------------WGFVVTKTFG------LDKDLVTNVSPRIVR--GTTSGYKYGPQQGCFLNIELISE-----------------------------KRAEYWLKSIGELKRDFPEKIVIASIMCSFNEEDWTELAIKAEQSGADALELNLS---CPHGMGERGMG--LACGQDPELVEQISRWVRKAVKLPFFIKLTPNITDIVS----------IAAAAKRGGADGGSAINTVQGLMG-----------------LKADSTAWPAIGK-----------------------EQRTTYGGVSGNATRPMALKAISDIANRVPGFPILGIGG-------------IDSGEVALQFIHAGATVLQICSSVQNQDFT--------VIEDYCTALKALLYLKANPPPVDGPFWDGQS---------------------PPTPVHQKGKPVVRLTGEGKATLGFFGPYQRQRDIKMAELRSQKGALWDAEQVKATPPASNGAPNP-APRIKDVIGAALDKIGSYNKLDNKQ------------------------------QKVALIDDDMCINCGKCYMTCAD--------SGYQAIEFDKDTHIPHVNDDCTG------CTLCVSVCP--------------------IIDCITMVPKKIPHVIKRGVEEKIFYTHALSQCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12680-1", "uniprot_id": "GLT1_YEAST", "id": "Q12680-1", "name": "Glutamate synthase [NADH]", "aln": "MPVLKSDNFDPLEEAYEGGTIQNYNDEHHLHKSWANVIPDKRGLYDPDYEHDACGVGFVANKHGEQSHKIVTDARYLLVNMTHRGAVSSDGNGDGAGILLGIPHEFMKREFKLDLDLDIPEMGKYAVGNVFFKKNEKNNKKNLIKCQKIFEDLAASFNLSVLGWRNVPVDSTILGDVALSREPTILQPLLVPLYDEKQPEFNETKFRTQLYLLRKEASLQIGLENWFYVCSLNNTTIVYKGQLTPAQVYNYYPDLTNAHFKSHMALVHSRFSTNTFPSWDRAQPLRWLAHNGEINTLRGNKNWMRSREGVMNSATFKDELDKLYPIIEEGGSDSAALDNVLELLTINGTLSLPEAVMMMVPEAYHKDMDSDLKAWYDWAACLMEPWDGPALLTFTDGRYCGAILDRNGLRPCRYYITSDDRVICASEVGVIPIENSLVVQKGKLKPGDLFLVDTQLGEMVDTKKLKSQISKRQDFKSWLSKVIKLDDLLSKTANLVPKEFISQDSLSLKVQSDPRLLANGYTFEQVTFLLTPMALTGKEALGSMGNDAPLACLNENPVLLYDYFRQLFAQVTNPPIDPIREANVMSLECYVGPQGNLLEMHSSQCDRLLLKSPILHWNEFQALKNIEAAYPSWSVAEIDITFDKSEGLLGYTDTIDKITKLASEAIDDGKKILIITDRKMGANRVSISSLIAISCIHHHLIRNKQRSQVALILETGEAREIHHFCVLLGYGCDGVYPYLAMETLVRMNREGLLRNVNNDNDTLEEGQILENYKHAIDAGILKVMSKMGISTLASYKGAQIFEALGLDNSIVDLCFTGTSSRIRGVTFEYLAQDAFSLHERGYPSRQTISKSVNLPESGEYHFRDGGYKHVNEPTAIASLQDTVRNKNDVSWQLYVKKEMEAIRDCTLRGLLELDFENSVSIPLEQVEPWTEIARRFASGAMSYGSISMEAHSTLAIAMNRLGAKSNCGEGGEDAERSAVQENGDTMRSAIKQVASARFGVTSYYLSDADEIQIKIAQGAKPGEGGELPAHKVSKDIAKTRHSTPNVGLISPPPHHDIYSIEDLKQLIYDLKCANPRAGISVKLVSEVGVGIVASGVAKAKADHILVSGHDGGTGAARWTSVKYAGLPWELGLAETHQTLVLNDLRRNVVVQTDGQLRTGFDIAVAVLLGAESFTLATVPLIAMGCVMLRRCHLNSCAVGIATQDPYLRSKFKGQPEHVINFFYYLIQDLRQIMAKLGFRTIDEMVGHSEKLKKRDDVNAKAINIDLSPILTPAHVIRPGVPTKFTKKQDHKLHTRLDNKLIDEAEVTLDRGLPVNIDASIINTDRALGSTLSYRVSKKFGEDGLPKDTVVVNIEGSAGQSFGAFLASGITFILNGDANDYVGKGLSGGIIVIKPPKDSKFKSDENVIVGNTCFYGATSGTAFISGSAGERFGVRNSGATIVVERIKGNNAFEYMTGGRAIVLSQMESLNAFSGATGGIAYCLTSDYDDFVGKINKDTVELESLCDPVEIAFVKNLIQEHWNYTQSDLAARILGNFNHYLKDFVKVIPTDYKKVLLKEKAEAAKAKAKATSEYLKKFRSNQEVDDEVNTLLIANQKAKEQEKKKSITISNKATLKEPKVVDLEDAVPDSKQLEKNSERIEKTRGFMIHKRRHETHRDPRTRVNDWKEFTNPITKKDAKYQTARCMDCGTPFCLSDTGCPLSNIIPKFNELLFKNQWKLALDKLLETNNFPEFTGRVCPAPCEGACTLGIIEDPVGIKSVERIIIDNAFKEGWIKPCPPSTRTGFTVGVIGSGPAGLACADMLNRAGHTVTVYERSDRCGGLLMYGIPNMKLDKAIVQRRIDLLSAEGIDFVTNTEIGKTISMDELKNKHNAVVYAIGSTIPRDLPIKGRELKNIDFAMQLLESNTKALLNKDLEIIREKIQGKKVIVVGGGDTGNDCLGTSVRHGAASVLNFELLPEPPVERAKDNPWPQWPRVMRVDYGHAEVKEHYGRDPREYCILSKEFIGNDEGEVTAIRTVRVEWKKSQSGVWQMVEIPNSEEIFEADIILLSMGFVGPELINGNDNEVKKTRRGTIATLDDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASVDKFLMDGTTYLPSNGGIVQRDYKLLKELASQV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **:: :: :* *.: ::: : : .. *.* . . .: .::..: * .*:* . : . . :*. :.*. :: : : *.* ::*. :*.. ::*.:. : * . : * :: *.* . *:: . :. : :. .: . . . * ::: *. :* : .: . . *:* : :* . ...:::* : :. *: : : :. . ::: * : . :* * . : : :: .: :. . ::* .. . *: : *.. :* *. . * * .* ::* :* * .* :..:* . :::.:.:: ... . .: * :..: : . : : :.* : :: .. *. .:** : *: :: : **::: * . .* . . .:..: *: . * : : * .: . *:. : .:: ** . :**. . :.: * : . * * : :::*. * :::*.:.. :: . : . *. . : .: **: . : : . * *: . : .: : . * : *.*::::** * : . *: :: ** :* .: . : . . :.: *. *: : .: . * :* . ..* .: . *:.*.. : . * **..**.: . : : . . : : * : * .*: : ..: : * : : :**. :*. * :: : : : * : ::*.:.. : * * . . : . .* ::*.: : . .:. . : * : *::**. : . . :: : *. : ::. . *. :* : * *:* * . : ", "identical_positions": 121, "similar_positions": 361, "identity": "5.64%" }, { "cls_id": "homologset.agr.MGI:2139714", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88923-7", "uniprot_id": "AGRL2_RAT", "id": "O88923-7", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIMIISFSPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCVVVTGSDVFPDPCPGTYKYLEVQYECVPYMEQKVFVCPGTLKAIVDSPSIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNVIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTVSTTSSTSQRGPVSSTVAGPQEGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALEMKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-TVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAETLDCWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTDNIVLEVAVLSTEGQVQDFTFHLGFKGAF--SSIQLSANTVKQNSRNGLAKVVFIIYRSLGPFLSTENATVKLGAD-LLGRNSTIAVN-----------------SHVLSVSINKESSRVYLTDPVLFSMPHIDSDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIVYKDG--VHKLLLTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTQYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDSKSYGTLEACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYAKCFRH------WYCCGGLPTESPHSSVKASTSRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPG------HSLNNTRDTSAMDTLPLNGNFNNS---YSLRKADYHDGVQVVD--CGLSLNDTAFEKMIISELVHNNLRGSNKTHNLELKLPVKPVIG----------GSSSEDDAIVADASSLMHG------DNPGLEFRH-KELEAPLIPQRTHSLLYQPQKKVKPEATD----SYVSQLTAEADEHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENED--------IYYKSMPNLGAGRQLQMCYQISR--------------------GNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZZ7-1", "uniprot_id": "AGRL2_MOUSE", "id": "Q8JZZ7-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIIIISFSPSTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYSKMLVFVCPGTLKAIVDSPCIYEAEQKSGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETAYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNTIDYIYNTRLSRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTISTTSSASQRGPVSSTAAGPQDGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALDWKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-HVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQVQDFKFPLGLKGLG--SSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGAD-LMGRNSTIAVN-----------------SPVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG--VHHLLLTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTVQACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYGKCFRH------WYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPAFNSPG------HSLNNARDTSAMDTLPLNGNFNNS---YSLRKADYHDGVQVVD--CGLSLNDTAFEKMIISELVHNNLRGGNKTHNLELKLPVKPVIG----------GSSSEDDAIVADASSLMHG------DNPGLEFRH-KELEAPLIPQRTHSLLYQPQKKVKPEATD----SYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENED--------IYYKSMPNLGAGRHLHMCYQISR--------------------GNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95490-1", "uniprot_id": "AGRL2_HUMAN", "id": "O95490-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIIVISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPY----IFVCPGTLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNSIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTIISTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVSTTKIPPITNIFPLPERFCEALDSKGIKWPQTQRGMMVERPCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-PVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAG--SSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGAD-FIGRNSTIAVN-----------------SHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG--VHELLLTVITWVGIVISLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENI------------------------KSWVLGAFALLCLLGLTWSFGLLFIN------EETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRH------SYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPG------HSLNNARDTSAMDTLPLNGNFNNS---YSLHKGDYNDSVQVVD--CGLSLNDTAFEKMIISELVHNNLRGSSKTHNLELTLPVKPVIG----------GSSSEDDAIVADASSLMHS------DNPGLELHH-KELEAPLIPQRTHSLLYQPQKKVKSEGTD----SYVSQLTAEAEDHLQSPNRDSLYTSMPNLRDSPYPESSPDMEEDLSPSRRSENED--------IYYKSMPNLGAGHQLQMCYQISR--------------------GNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GRP1-1", "uniprot_id": "A0AC58GRP1_DANRE", "id": "A0AC58GRP1-1", "name": "", "aln": "MWKAESPVRARMGCSEWKSLVLCGLVFVLTVVQSSDGFSRAAMPFGLVRRELSCEGYPIDLRCPGSDVIMIETANYGRTDDKICDADPFQMENINCYLPDAFKIMSQRCNNRTQCIVITGPDVFPDPCPGTYKYLEVQYECVPY----IFVCPGTLKAVGDPSFLYEAEQQAGSWCKDPLQAGDKVYFMPWTPYRTDTLIEYNSLDDFQNSRQTTTYKLPHRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINNANYHDTSPYKWGGKTDIDLAVDENGLWVIYATEQNNGMMVISQLNPYTLRFEATWETTYDKRSASNAFMICGVLYVVRSTYEDNESEVSKSLIDYMYNTKLNHGEYVDIHFPNQYQYIAAVEYNPRDNQLYVWNNFYILRYNLVFGPPDPAHAPPISEASTSPKVLKPTTTTTTTTQPKGQVTTITTTGTRAVNKTPKSPPVLPQTTTPPSLESFPPPERFCESVELRDILWPQTQRGMLVERPCPKGTRGTASYLCVLSTGTWNPKGPDLSNCTSHWVNQVAQKIRSGEN-AANLANELAKHTKG-AIFAGDISSTMRLMEQLVDILDAQLQELRPSEKDSTGRSFNKLQKRERTCRAYMKAIVDTVDNLLRPEALKSWRDMNTTEQTHAATMLLDTLEEGAFVLADNLMEPAIVKVPASNIILDVYVLSTDGQVQDFRFPQSGRGG---ISIQLSSNTVKLNSRNGVAKLVFALYKNLGQFLSTENATMKLGQE-VNGRNLSVAVN-----------------SDVIAASINKESSRVFISEPVIFTLEHIDMQHYYNSNCSFWNYSERTMMGYWSTQGCKLIHANKSHTTCSCSHLTNFAVLMAHRELLGADK--VQELLLSVISRVGIVVSLICLAMSIFTFCFFRG--LQSDRNTIHKNLCINLFIAELIFLIGIDMTEPKLACSIIAGILHYFFLASFAWMCLEGVQLYLMLV----EVFESEYSRRKYFYMAGYLLPAVVVGVSAAVDFRSYGTKKACWLRMDNHFIWS-FIGPVTFIIMLNLIFLLITMYKMMKHSTS--LKPDSSRLEHIN---------------YEDNKPFIKSWVMGGFALLCLLGLTWSFGLFFIS------ESSVVLAYLFTIFNTFQGMFIFTFHCLLQKKVRREYSKCLRH------TYCCSRITTESSHSSTKTSTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGKTKHKTISEPLEGMTGNYLLTNPLLRPQGTNNPYNTLLAETIVCNTPTVPVFHSPVTYRETRHSVTSGRDTNTFGTLPLNGNFNNS---YSLHN--YSDGMQVVD--CGLSLNDTAFEKMIISELVHNNLR------AAESRIGTKKGAG----------ISRGEE-PVVAETSSLVQVGGDSEMERLGLHHTHPRTLEAPLIPQRTHSLLYHTQERARPEAEASHPQSYIGQLPPPAETALPSPNRDSVYTSMPNLRDSPFSESSLDIVQDLSPSKNSPNED--------VYYKSMPNLGSGQQLHAYYQMSR--------------------DSSEGLIIPVSKDACVPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GDD5-1", "uniprot_id": "A0AC58GDD5_DANRE", "id": "A0AC58GDD5-1", "name": "", "aln": "---MASSLWKRS--------LVLALLLTVIFLQPSEGFSRAALPFGLVRRELSCEGYPIDLRCPGSDVIMIETANYGRTDNKICDADPFQMDNINCYLPDAYKIVSQRCNNRTQCVVNTGSDVFPDPCPGTYKYLEVQYECVPY----IFICPGTLKAVGDPTLEFEAEQQSGAWCKDPLQAGDKIYFMPWTPYRTDTLIEYASLDDLRSGRQTTTYKLPHRVDGTGFVAYDGAIFFNKERTRNIVKFDLRTRIKSGEAIVASANYHDTSPYRWGGKTDIDLAVDERGLWVIYATEQNNGRIVLSQLNPYTLRFEATWETVYDKRSASNAFMVCGVLHVVRSTYEENESEASKSQIDYVYNTKLGQGEYVNILFPNKYQYIAAVDYNPRDNQLYVWNNFYILRYNLEFGPPDPDEEPTVSDDATSTLPPRRSTPAVLKTTLSLSFTQRPSLNSSISTDPLTEEHPEPPADPTAAASVPPASRRFCEPTEKRGISWPKTHRGLTVERPCPRGTRGIALFLCLTG-GVWNPKGPDLSNCTSHWVAQVAQKIRSGEN-AASLANELAHHTQG-SVFAGDVSSSVRLMEQLVDILDAQLQELKPDQKDSPGRSFNKRQKRERTCRAYMKAIVDTVDNLLRPEALKSWEDMNSTEQTHAATMLLDTLEEGAFVLADNLIEPAVVRMPAENIMLDVYVLSTDGQIQDFRFPQTSKRG---ATIQLSANMVKLNSKNGVAKLVFVLYKHLGHFLSTENATVRLMGD-GGLRNHTLTVN-----------------SHILSASINKESSRVFVSEPVIFTLEHLDTENYFNPNCSFWNYSERSMSGYWSTQGCKLLSTNKTHTTCSCSHLTNFAILMVHRDSHAGEGS-VHELLLTVITRLGIAVSLVCLAISIFTFCFFRG--LQSDRNTIHKNLCINLFIAELLFLVGINMTEPPIVCSVIAGVLHFFFLAAFSWMCLEGVQLFLMLV----EVFESEFSRRKYYYASGYLFPCVVVGISAAIDYKSYGTKKACWLRVDNHFIWS-FIGPVTFIILLNLIFLVVTMYKMVKHSMS--MKPDSSRLESIR------------------------SWVFGAFALLCLLCLTWSFGLLFLN------DSSVIMAYLFSIFNTLQGMFIFVFHCLLQKKVRKEYSKCFRQ------SQCCRTHPSEGPHSVNKSSASRSTARYSSATQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHDTNNRYNNLLAETIVCSTPSPPAFHSPG-----QRSLSNSRDVSTMDTLPLNDNFNNS---YSLREDDYEDPAITCPTGCEIRLDDAAFEKMIISELVHNNLRPRRNQSSSKCQADRNSSPQENCADIDEGVGDRNECENAETDTSAMPLSSCHPAMELLLLNPNHREALEVPLLPQRTHSLIYASQKVIRPHKISR--DTQQDEGEVKKEDDSSPNNRDSLYTSMPNLKDSDLVIG--EEENSPCSSAQSETQE--------QCCKSLPDLGDGTPAMSYYQISA--------------------SLS------------LEAESANDGQMQLITSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "----------------------------MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISA-------------------------AQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVG----AGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQ-----LHHHHNHHGEDTASPTKPSSKLPAGGNATSP---SNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCG--------------PTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPD----SGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLR---------------------NFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFP------------DQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGK-GRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDH----AWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVR------------------------FDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAG---STHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASP---------SGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .:.: :: :. : :*** : :.* .*** : ***** . .**: . . :* :*.: .::..** :: .* * :...:* ******:****.:*:*:. ::.: : * . : * . . **. .: . ... :** . .*: * . . ::* . : * . : . *:. : .*: * . : :: .:::* . * :* : . * : :. : * . .. .:*. .: .: : . * : * *.:. . :.:*: * . .. . . . . : .. **. : * .*:* ***::* * *: :: ::.. :. .:**:::. *.. ::.**: : :::: : : : : : : . ::** ::.:*.* .*** . *..* .:*. :* :.** ** ** .**:***.::. * ..**:*.* **.*. ... * : *:*. : **..*:.::** : * :*... . * . ** :: * * :::.*:.* . :: :::*: ::: *:. :: *..* **** :: **::**.* :*::::.*:*.******:** : . : . : :: :.* :.:: :.:.::*: :*.* ::* *.:*:..: : *: *::**:**: *: : * .:: .** :*:. :*:* *..: : *. : .: .: : :* .* :. **.:* .:* :* . * * * :::: *: ** .::: : : .:: * ::* : . : :** : : .*.:* ** .*. . ::: : : : .* * **:: *::** *** ::*:*:** * .*: * . .. : .:: : . *:..:.:: .: .:.:.:.. : : .:: . . *:*..* * * . : * : : .: . *. . :: . **. .: :. ** :: . :* . *:.: . : : . . :. : : . *: ** . .: : *: : . : : : : . :: :. . . .:. . .:* . :: . * : . . * .* . ", "identical_positions": 227, "similar_positions": 470, "identity": "12.15%" }, { "cls_id": "homologset.agr.MGI:2139736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA20-1", "uniprot_id": "D4AA20_RAT", "id": "D4AA20-1", "name": "Zinc finger protein 697", "aln": "MSFVQPHRKPQREGSGQPARVPARGPIAAASGRRAGARLGQCAQESPGASQGPCFPPCSLSCWMEQEDNLGVCADQSSEDRGMGSDFENSEDQEGDPEERGVGSNPQDTEER-GHLEQELDSNPQDDDLRGDPPERDIVSTVCSEGLLSEEEGAILREEEDDQPGVADMALFPGLSESDSITRSPQGEEEEEEE-EEEESAGENRLIEKEEPLPTPVLPWRRHLSLGGRHRGDKPAYRRFHRLHHPMAVDLGELDSLMASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAMASLEPFGLAGECGGVVGMMG----VGMGVSGGFGAGPTLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAAGGAGSAAAAAAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKR-THSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFSCGQCEKRFSDFSTLTQHQRTHTGEKPYTCLECGKSFIQSSHLIRHRRIHTGNKPHKCTGCGKGFRYKTHLAQHQKLHLC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q569E7-1", "uniprot_id": "ZN697_MOUSE", "id": "Q569E7-1", "name": "Zinc finger protein 697", "aln": "---------------------------------------------------------------MEQEDNQGVCEYQTSEDRGMDSDLENSEDREGDPEERGMGSNPWDTEDR-GHLEQEVDSNPQDDDLRGDSRERDRASTVCSEGRLSEEERAILREEEDDQPGVADMALFPGLSESDSISRSPRGEEDEEEEDEEEESAGENRLIEEEDPLPTPVLPWRRHLSLGGRHRGDKPAHRRFHRLHHPMAMDLGELDSLMASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAVASLEPFGLAGECGGVVGMMGMGMGVGMGVAGGFGAGPTLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAAGGGAGSAGSAAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKR-THSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFGCGQCEKRFSDFSTLTQHQRTHTGEKPYTCLECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TEC3-1", "uniprot_id": "ZN697_HUMAN", "id": "Q5TEC3-1", "name": "Zinc finger protein 697", "aln": "---------------------------------------------------------------MKQEDNQGVCAHQDSEDKGMGSDFEDSEDREGDPEEREMGSNPHDTNKREGHPEPEMGSNPQD------SRHREAVPDICTEGQLSEEEGVSVRGEEDDQSGVADMAMFPGLSESDSISRSLREDDD--------ESAGENRLEEEEEQPAPPVLPWRRHLSLGSRHRGDKPAHRRFHRLHHPMAVDLGELDSLVASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAAASLEPFGLAGECDAMVGMMG------VGVAGGFGAGPPLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAASGAG-----AAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKR-THSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFRCGQCEKRFSDFSTLTQHQRTHTGEKPYTCIECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B621-1", "uniprot_id": "A0ACD6B621_DANRE", "id": "A0ACD6B621-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MSDPEPCRIKQE-----------------------------EAEELIDLIEENEESKEIKPHVKAET-----------LPQLQTFDTY------------------------FIKEEE-------------SQECKNG----------------------------------CVCTQCGKRFRLSSALEKHMRIH--------------------------------------------------TGEKPFTCTQCGKSFGRLSHLNKHMRIHTGERPFTCTQCGKSFTRSYYLNLHMMIHTGE-----------------------------------------RPHNCDQCGKTFMRSSQLKMHLRVHTKEKPYSCSECGKSFTQQSNLRKHQKIHTGLKEHMCLECQQTFVTAGQLKQHQR-IHTGEKPYTCSHCKKRFNQSGSLKTHQMIHTGEKPYKCSHCNKRFSQSGSMKAHERIHTGEKPYTCDQCLKSFTHLFQRNKHMKIHKGEKQHT-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AUK5-1", "uniprot_id": "A0A8M3AUK5_DANRE", "id": "A0A8M3AUK5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MSDPKPCKIKQE-----------------------------ETDDRQNMNDPEPCG---------------------------------------------------------IKQEE------------------------------------------------------------------TDDREHMN--------------------------------------------------------DPETCGIKQEETEDTENMSDPE---------------------------------------------------------------------------------------LKEEETEEQTDLNESEE--------SEYDERKDLKKRRRKK-------CLTCSQTFVTAGQLKRHQV-IHAGETKYTCSHCGKAFTQVQNLKRHERIHTGEKPYKCSHCDKSFTQLPNLKCHERIHTGEKPYRCQQCLKRFTQLSQLQKHTNMHR-KAGHVI----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHR4-1", "uniprot_id": "Q9VHR4_DROME", "id": "Q9VHR4-1", "name": "", "aln": "---------------------------------------------------------------MSPPSGEFRCRVCLKQDELLVDIYEIVEEMQVDLCTLLETCG-------------------------GIKVDRRDVQPMYLCQECTNELLIAAKFRKICVESEKLRDMAPEIN------------------------------IDTAEP------------------------------------------------------LASEEIIIIDPSDYIEQLSAVED--------------------------------------------PENEPIGVSRWNCQHCGAGFQLSEVLRRHIQEVHASITIIDCRERRRIFTKLGCYQVHNCSYAKTPK--------------------------------------RGHKCLECGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRRHKQVLQHKCLHCGRGFVESSNLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFAQLGVLKIHERIHTGERLHRCQVCEKPFTRAGQLRKHALRHETGQ--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . : : . * : . : :: * . : . * ::: : * * . * :.:* * *: * : * : * : * * :***:*: * : :* *:: :. *:* ****: : * * * * : : :* * ", "identical_positions": 34, "similar_positions": 41, "identity": "5.36%" }, { "cls_id": "homologset.agr.MGI:2139740", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M317-1", "uniprot_id": "A0ABK0M317_RAT", "id": "A0ABK0M317-1", "name": "Protein phosphatase 1L", "aln": "--------------------------MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKSHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLP----------------------------EALKQHLQDYEKDK-------------------------------------------------------------------------------------ENSVLTYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRN----------SSKTEEQ-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHN0-1", "uniprot_id": "PPM1L_MOUSE", "id": "Q8BHN0-1", "name": "Protein phosphatase 1L", "aln": "--------------------------MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKSHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLP----------------------------EALKQHLQDYEKDK-------------------------------------------------------------------------------------ENSVLTYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRN----------SSKTEEH-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SGD2-1", "uniprot_id": "PPM1L_HUMAN", "id": "Q5SGD2-1", "name": "Protein phosphatase 1L", "aln": "--------------------------MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKNHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLP----------------------------EALKQHLQDYEKDK-------------------------------------------------------------------------------------ENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRN----------SSKTEEQ-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QD96-1", "uniprot_id": "F1QD96_DANRE", "id": "F1QD96-1", "name": "Protein phosphatase 1L", "aln": "-------------------------------MSPLALLARTLRCVLLRPGGLLLLGFSLALWSFIFHTGELQGLLQMLR-GRAAGPGLPVPLLPRD-----GPPEEQLSNTWQLRSGAAAVYSIQGRRDHMEDRFDILTDTRNRSHPAIFSIYDGHGGEAAAEYAKAHLP----------------------------IMLRQQLQRYERQK-------------------------------------------------------------------------------------ENSAVSRQAILRQQILNMDREILEKLTASYDEAGTTCLVALLSEKELTVANVGDSRAVLCDKDGNAIPLSHDHKPYQLKERKRIKKAGGFISFSGSWRVQGVLSMSRSLGDFPLKKLKVLIPDPDLMTFDLDTLQPQFMILASDGLWDTFSNEEAVHFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFKK----------RAGNKD------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ28-1", "uniprot_id": "Q9XZ28_DROME", "id": "Q9XZ28-1", "name": "PPM-type phosphatase domain-containing protein", "aln": "MDDELEDKVFYQTYVSHMKILSKFAVGFSSINSPLAYIWKLCRLYVLRP-EVIFCGLILFVLLLYLQAVDVWSRSILGRIQATLGRQKAVKMMELS-------ASAGDHQSWEEMKQQSSAFAVLGRRPRMEDRFIIEENINNNTGISFFAVFDGHGGEFAADFAKDVLVKNIYNKIIEMSKLLKTEGNSGDYDKSPYLARKQSRKDANKENTEPTAGVMRKDSLRKAHSTTADCSAIKQKTTEASIADIYTVQLNSAMRASGNLGAAKDSFLNNNNNGQNGAANAPPPNYEAKCYIEHGRINFGKLITDEIMSADYKLVEQAKRATNIAGTTALIAIVQGSKLIVANVGDSRGVMYDWRGIAIPLSFDHKPQQVRERKRIHDAGGFIAFRGVWRVAGVLATSRALGDYPLKDKNLVIATPDILTFELNDHKPHFLILASDGLWDTFSNEEACTFALEHLKEPDFGAKSLAMESYKRGSVDNITVLVIVFKNDVYKIGSSAGKAGEESLKVPAKSQPVAPAVVQRSNSIKTK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : : * :*** ::: : * : ::: :: * . :: . . ::*: . :.::: *** :***** : : *.: ::*.::****** **::.* * :* : :::: *:. :. :: ::*:. * :::*: . : : ****.*:*::. ..* ********.*: * * *****.**** *::*****: *****:* * *** *:*: **:***:***. :::*. **::**:*: :*.*:*********:****** * *:*.**.*****:.::*: **. *****:*: *:: : :. ", "identical_positions": 129, "similar_positions": 112, "identity": "24.25%" }, { "cls_id": "homologset.agr.MGI:2139743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WL0-1", "uniprot_id": "ES8L3_MOUSE", "id": "Q91WL0-1", "name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "aln": "--------------------------------------------------------------MSRPSSRAIYLHRKEYSQSMASEPTLLQHRVEHLMTCKLGTQRVREPKDALQKLQEMDAQGRVWSQDLFLQVRDGWLHLLDIETKEELDSYRLDNIKAIDVALNTCSYNSILSVTVQESGLPGISTLLFQCQEVGAEQLRTSLQKALEEELEERPRFGVHHPSQDRWKGPPLERPLPIQQAPPLEQRFSPEHRFPPEQP------HNMTSERSISPSSRSLTHYPSAREPNGFTLPPPPRRAPSPE-----DPERDEEVLNHVLRDIELFAGKLKEVQARN--SHKKTKLGRKKKKSKNGITQAEYIDCFQKIKLSFNLLGKLALRMQETSAPEFVGLIFQTLKFILSQCPEAGLPAKVISPLLTPKAIDLLQSCLSPPEDTLWKSLGTSWTTSWADWT--GSEPPPYQPTFYDGWQIPQPRSMMPITNQDSISLR--GSRMR-SSLHFPRDEPYNHNPEYEDSNLPLSSPSPGRAALKMQVLYEFEARNAQELTVAQGEILEVLDQSKRWWLVKNEAGLTGYIPSNILEPLPAGAPRGHRQPSFRAPMLRLSSKPEEVTAWLQAENFSTVTVRTLGSLMGSQLLHMRPGELQMLCPQEAPRIQARLDAVRRMLGMTH----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R3R8-1", "uniprot_id": "M0R3R8_RAT", "id": "M0R3R8-1", "name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "aln": "MTQIGLQNVLQVQVGLCLRRWQRSQNRTPSDNTGPLAQASASLGDQTPDCTGNQEAVLSSVDMSRPSSRAIYLHRKEYSQSLASEPTLLQHRVEHLMTCKLGTQRVREPKDALQKLQEMDAQGRVWSQNLFLQVKDGWLQLLDIETKEDLDSYRLDNIKAIDVALNTCSYDSILSVTVQESGLPGISTMLFQCQEVGAEQLRTSLQKALEEELEERPRFGVHHPGQDRWKGSPLQRPIPIHQAPPLEQRFSPEPRFPPERP------HDMTPERSITPSSRSLTHYPSAREPNGFTLPPPPRRAPSPE-----NPERDEEVLNHVLRDIELFSGKLKEIQAKN--SHKKIKLGRKKKKYQKEITQAQYIDCFQKIKFSFNLLGKLALRLQETSAPEFVGLIFQTLRFILSQCPEADLTTKVISPLLTPKAIDLLQSCLSPPERTLWKSLGTAWTTSWADWT--GSEPPPYQPTFYDGWQIPEPYSTKPLRNQDSLSLR--GSRMR-SSLHFPQDEPYNDSREYEDSNLPLPSPSPDRTALKMQVLYEFEARNAQELTVAQGEILEILDQSKRWWLVKNEAGLTGYIPSNILEPLPAGAPRGHRQSSFRAPMLRLSSKPEEVTAWLQAENFSTVTVRTLGSLVGSQLLHMRLGELQMLCPQEAPRIQARLEAVRRMLGMTH----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TE67-1", "uniprot_id": "ES8L3_HUMAN", "id": "Q8TE67-1", "name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "aln": "--------------------------------------------------------------MSRPSSRAIYLHRKEYSQNLTSEPTLLQHRVEHLMTCKQGSQRVQGPEDALQKLFEMDAQGRVWSQDLILQVRDGWLQLLDIETKEELDSYRLDSIQAMNVALNTCSYNSILSITVQEPGLPGTSTLLFQCQEVGAERLKTSLQKALEEELEQRPRLGGLQPGQDRWRGPAMERPLPMEQARYLEP------GIPPEQP------HQRTLEHSLPPSPRPLPRHTSAREPSAFTLPPP-RRSSSPE-----DPERDEEVLNHVLRDIELFMGKLEKAQAKT--SRKK-KFG-KKNKDQGGLTQAQYIDCFQKIKHSFNLLGRLATWLKETSAPELVHILFKSLNFILARCPEAGLAAQVISPLLTPKAINLLQSCLSPPESNLWMGLGPAWTTSRADWT--GDEPLPYQPTFSDDWQLPEPSSQAPLGYQDPVSLRRGSHRLG-STSHFPQEKTHNHDPQPGDPNSRPSSPKPAQPALKMQVLYEFEARNPRELTVVQGEKLEVLDHSKRWWLVKNEAGRSGYIPSNILEPLQPGTPGTQGQSPSRVPMLRLSSRPEEVTDWLQAENFSTATVRTLGSLTGSQLLRIRPGELQMLCPQEAPRILSRLEAVRRMLGISP----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JIS3-1", "uniprot_id": "B8JIS3_DANRE", "id": "B8JIS3-1", "name": "", "aln": "-----------------------------MYGGNPVFQPRGFSP----------EPSSQGSGMSRPSAKSIYMQRKEYAESMSRQ-DSFQYRVEHLFTCALDGREVSSIDDCVNRLKILDSKGKIWGQDMIIQIQANHLQLCDIETKEVLESVHLNSIRKAKAVLDSCVYDSLLIISAQEPSQRFPQAFLFQCEEAGAQEVANDLEKSIQQGGDASPPIKEPQMDIRSHLESIIGQGYPGN---VKRPIQ--SNPPPPDFPPPQYNSYEDYGDHYDDRRPSPTMQFPRDEVPFRPVQSE---REQTPP--PFNDVNRDIEILNHVAADIETFTYKVGSALPKDDGSKKKKKKNAPKAPVANIPTVEEYVSCLQKIKYGFNILGKLDGHLKNPPAPDFVHSLFSSLGFIMSHYPPN-IPPSVLSPLLTENALQLLGRVVTPNEDKLWSSLGDAWNIPRSKWP-NGDQIPPYYPEFYDGWQP---LPPGP-----SQSPPANRQLSRSNSERFPPANASQRPPEQDNRAWNPPPMKLAELPLLMRVIYDFMARNSQELSVMKGDMVQVIDKSGQWWKVKNSRNEEGYVPQNVLEPVDGERPPQQNMRG--PPSLDMKSRPEEVKAWLQYKGFSKTTIQNLGILDGAMLLRMKRDEIRAICPEEGGRVFFQLQSVRSTVALANEAQFSQYGGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F362-1", "uniprot_id": "E7F362_DANRE", "id": "E7F362-1", "name": "", "aln": "----------------------------MLRDSSPFGWSGGYAESLRSSVTAADESSSDVLDLSRPSAKSIYHQRKEYAESVNRQMHQFQHRVEHLFTCELDGQQLCDVDDCLERLKYLDATGRVWGQDVILEVQDAALRLADIETREVLESWPLSCVLELKAVLDESVYDSLLTVSVQERGSRTVSVFMFQSETLRADYLKKDLQRLLQNSRDDPRQSNSSKAAVGNITQKNSRRASPPPELILQRPAERWAAPDYDDSPVATPPTSRNNSTHTKVVAPPPQTKTPPHKQTTPPRTEEPPVREAPPPQKPYTERERNVDILNHLINDIEAFVGRLTAVAPKMDKKKKKQKK---QKAVKGMPSDEEFTVCLRKIKMAFNLLGKLQGKIDNPSAAELTHCLFSILELVVYHCNED-LPPSIVAPLFEPECVVFLSEEATPEEDHLWQSLGDAWNIPSTKWPEDDDDIPTFTPVFDDGWEPPAIRNPEPTYKQISKQEPAYKSISKEDTPRTSVARQMSRTAEP---ELEPEQSELPAS--FMRAIFDFSARNDRELSITKGEELQLLDMSKKWWKVKNQRGQIGFVPNNMLQQQNQEEE-KEEAPS--APALNRKSRPEEVRAWLEHKGFSKITVRCLGGVSGSMLLGMTRDELKTICPEEGGRVFYQLQNIKSALAMASEVRPMI----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****:::** :****::.: : :*:*****:** . :.: .*.:::* :*: *::*.*::::::: *:* ****:* *:* *. : ...*: . *:*:* ::.** . ..::**.: *: : ..*:: ::: : : : * . : * : . . : . . . * .* : :*: ::***: *** * :: .: .:** * : : :: *::*** .**:**:* :.:..*.::. :*. * ::: : :...:::**: :.: :* :* * ** .** :*. . :.*. ..: .: * * *.*: * . . .: : . . . : . *:.:::* *** :**:: :*: ::::* * :** ***. . *::*.*:*: . * * .*:**** **: :.**. *:: ** : *: ** : .*:: :**:*. *: :*: :: :.:: ", "identical_positions": 129, "similar_positions": 200, "identity": "18.7%" }, { "cls_id": "homologset.agr.MGI:2139744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14CN2-1", "uniprot_id": "CLCA4_HUMAN", "id": "Q14CN2-1", "name": "Calcium-activated chloride channel regulator 4", "aln": "MGLFRG-FVFLLVLCLLHQSNTSFIKLNNNGFEDIVIVIDPSVPEDEKIIEQIEDMVTTASTYLFEATEKRFFFKNVSILIPENWKENPQYKRPKHENHKHADVIVAPPTLPGRDEPYTKQFTECGEKGEYIHFTPDLLLGKKQN-EYGPPGKLFVHEWAHLRWGVFDEYNEDQPFYRAKSKKIEATRCSAGISGRNRVYKCQGGSCLSRACRIDSTTKLYGKDCQFFPDKVQTEKASIMFMQSIDSVVEFCNEKTHNQEAPSLQNIKCNFRSTWEVISNS----EDFKNTIPMVTPPPPPVFSLLKISQRIVCLVLDKSGSMGGKDRLNRMNQAAKHFLLQTVENGSWVGMVHFDSTATIVNKLIQIKSSDERNTLMAGLPTYPLGGTSICSGIKYAFQVIGELHSQLDGSEVLLLTDGED-NTASSCIDEVKQSGAIVHFIALGRAADEAVIEMSKITGGSHFYVSDEAQNNGLIDAFGALTSGNTDLSQKSLQLESKGLTLNSNAWMNDTVIIDSTVGKDTFFLITWNSLPPSISLWDPSGTIMEN--FTVDATSKMAYLSIPGTAKVGTWAYNLQAKANPETLTITVTSRAANSSVPPITVNAKMNKDVNSFPSPMIVYAEILQGYVPVLGANVTAFIESQNGHTEVLELLDNGAGADSFKNDGVYSRYFTAYTENGRYSLKVRAHGGANTARLKLRPPLNRAAYIPGWVVNGEIEANPPRPEIDEDTQTTLEDFSRTASGGAFVVSQVPSLPLPDQYPPSQITDLDATVHEDKIILTWTAPGDNFDVGKVQRYIIRISASILDLRDSFDDALQVNTTDLSPKEANSKESFAFKPENISEENATHIFIAIKSIDKSNLTSKVSNIAQVTLFIPQANPDDIDPTPTPTPTPTPDKSHNSGVNISTLVLSVIGSVVIVNFILSTTI----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6Q473-1", "uniprot_id": "CLA4A_MOUSE", "id": "Q6Q473-1", "name": "Calcium-activated chloride channel regulator 4A", "aln": "MAFSRGPVFLLLLLYLLWGSDTSLIRLNENGYEDIIIAIDPAVPEDTTIIEHIKGMVTKASTYLFEATEKRFFFKNVSILIPESWKDSPQYRRPKQESYKHADIKVAPPTVEGRDEPYTRQFTQCEEKAEYIHFTPDFVLGRKQD-EYGDSGKVLVHEWAHLRWGVFDEYNEDQPFYSASSKKIEATRCSTGITGTNRVYACQGGSCAMRRCRTNSTTKLYEKDCQFFPDKVQSEKASIMFMQSIDSVTEFCKKENHNREAPTLHNKKCNYRSTWEVISTS----EDFNSSTPMETSPSPPFFSLLRISERIMCLVLDVSGSMTSYDRLNRMNQAAKYFLSQIIENRSWVGMVHFSSQATIVHELIQINSDIERNQLLQTLPTSANGGTSICSGIKAAFQVFKNGEYQTDGTEILLLSDGED-STAKDCIDEVKDSGSIVHFIALGPLADLAVTNMSILTGGNHKLATDEAQNNGLIDAFGALASENADITQKSLQLESKGAILNNSLWLNDTVVIDSTLGRDTFFLVTWSKQAPAIYLRDPKGTQTTN--FTMDSASKMAYLSIPGTAQVGVWTYNLEAKENSEILTITVTSRAANSSVPPITVNAKVNTDTNTFPSPMIVYAEVLQGYTPIIGARVTATIESNSGKTEELVLLDNGAGADAFKDDGVYSRFFTAYSVNGRYSLKVRADGGRNSARRSLRHPSSRAAYIPGWVVDGEIQGNPPRPETTEATQPVLENFSRTASGGAFVVSNVPSGPLPDLYPPNQITDLQATLDGEEISLTWTAPGDDYDVGRVQQYIIRTSKNIIELRDNFNNSPRVDTTNLTPKEANSEETFAFKPENITEENATYIFIAIESVDKSSLSSGPSNIAQVALFTPQAEPD-------PDESPS-----SSGVSVATIVLSVLGALVLVCIIVGTTICILKNKRSSSAAITKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3APN3-1", "uniprot_id": "A0A8M3APN3_DANRE", "id": "A0A8M3APN3-1", "name": "", "aln": "MHLRS----VFVLLWMLRLSTSTGIKLDGNGYIDITIAISSKVPEDDKLIDKIKDMVTEGSVHLYKALDKKVYFKEVTILVPLNWN-SKGFTKARTELFETGMIRIDNPHPAYGDEPYTNQYGECGAEGQYIHFTPNFLRDDKLIRLYGSRGKVLVHEWAHLRWGVYDEYSEKTPFYRSASGKIEATRCSKNIEG--QLYDVTAD--PLQPCQNDPQTSLPTDGCRFIPNKYQSTDSSMMSLPSLDSVITFCRESEHNYEAPNLQNAKCSNKATWTVIFEDSVDKDALRSLKPMASTPPAPNFKVVQRMQRTVCLVLDVSGSMKG-SRILRLQQASAHFLQNIIEDQSSVALVTFSTDASTLSALTTIDKESTRENLVKLLPNVAEGATNMCKGLNLGLQVLKTDNQDVLGDEIIFLTDGEATDTLSNCVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDVLSNQLLNGFSSLIMPTGNQTKDPVQIDSVG--IKTSDWFNGTVSVDQTIGTKTSFTITYETKLPRISIQSPSGLTYSQTQMRHDEPAKTVTLKVPGTAQTGDWKYSILS-PTLQSLTVTATSQAARANVPPITVKAQMNQQFSDGSKPMIVFAEVVQNYKPLIKAEVWATLESESGTVHELQLLDNGAGADTFKDDGVYSRYFTRMK-KGRSSLKVRVKNKDGQARFTLQK-RGGAPYVPGYVVNGVVELNPPKLSVSEELP-EVGSFTRTATGESFEVSLTSSK--PPKFPPCKIIDLSAEIQEDAVLLSWTAPGEDLDEGSAKSYDIRWSFEVKDLLFNFSNAHVVNTSVISPQVFGSVEQHLFN-LSFPIQNGTILFFAIQSEDNEKLKSEMSNVASGLQIIPNPNTG------------------DLDLKLIFIAISVCLASVVVIGIFGITTWALTRKKLSDS-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 331, "similar_positions": 316, "identity": "35.06%" }, { "cls_id": "homologset.agr.MGI:2139746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMJ4-1", "uniprot_id": "D3ZMJ4_RAT", "id": "D3ZMJ4-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSLRRDHKPSKEDGDVLEPCEEEATAALGGAFTGGRSGAGGSGKGGKACHKIFS-HHHRLQLKAPTAPG--PGVPAPPQHN-AVTATCPAPACLG-SNP-VVVADGGSCPSLYPVHECVFKGDVRRLSS--LIRTHN--IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVGEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFSGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVG-NFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGSLTEQN---------------------------FEPVRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATVAMSQEFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRC-DEFDGSIFAIPEDYKEDPSRFPDL------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UX43-1", "uniprot_id": "AN13C_MOUSE", "id": "Q3UX43-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSLRRDHKPSKEDGDVLEPCEEEATAALGGAFTGGRSGPGGSGKGGKACHKIFS-HHHRLQLKAPAVPG--PGVPAPPQHN-AVTATCPAPACLGGSNP-ALVADGGGCPSLYPVHECVFKGDVRRLSS--LIRTHN--IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVGEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVG-NFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGSLAEQS---------------------------FEPVRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATVAMSQEFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRC-DEFDGSIFAIPEDYKEDPSRFPDL------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6S4-1", "uniprot_id": "AN13C_HUMAN", "id": "Q8N6S4-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIG-----KGGKACHKIFSNHHHRLQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECVFKGDVRRLSS--LIRTHN--IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVG-NFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQN---------------------------FEPIRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRY-DEFDGSIFTIPDDYKEDPSRFPDL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUV0-1", "uniprot_id": "AN13C_DANRE", "id": "Q7ZUV0-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSVRKERKSG---LDLLEP--DEEPAATG--------------PAKHRGSKIFSGGNHRIS-RSSSSPG----------------------------DP-----DG-----AYPVHECVFRGDVRRLSS--LIRTQN--IAQKDVHGNTPLHLAVMMGHKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEDKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFCGDAPPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDVYSATLSTKSITFSRAQTGWLFREDKTERVG-NFLADFYMVNGLVLESRKRREHLSEEDILRNKAIMESFSKGGSLIEQN---------------------------FEPMRRQSLTPPSPNTISWEEYITAETGKAPHLGRELVCKESKKNFKATVAMSPDFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRY-DEFDESIFTIPSDYKGDPSRFPDL------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFB5-1", "uniprot_id": "A0A0B4KFB5_DROME", "id": "A0A0B4KFB5-1", "name": "Ankyrin repeat domain-containing protein", "aln": "MSKEKEDECDKHKQQATADAKSTSSEDSDEYQSAGEGEDGDGDG-----DGDSPAERPPDKTSPTVAVAPTAKAA----------------------------SP-LPTVKPASEALDFPMHRSVFEDDIKSLQRRLLLSTAQDEVGRKDKHGNTPLHLAVMLGRKHAVRLLLAQNAPVKIKNNEGWSPLSEAISYGDRQTITQVLRMLKLQSREHMESRREKLVNALRQMQDFYMEFKWDFQSWLPLVSRILPSDICRLYKSGASIRLDTTLVDFNDMRWERGDISFLFRGEAPARESLVLLDNEQECFQRLRYEES--DMEDEVDVLMSTDILATQMSTKTIQFARAQRGWIFRANRKELIGGQYQCEIYTIQGLILKQRKRREHLSHEDLQKNRAIVETITKGASQQPDTRRSSLGSQHTATPPETNTPTAPNGISLPELPRRSSLQAPPPPTVTWRQYLDAEVGKCPQLGRTPVHKQSNKTLRATVAMSKDFPLSVDMLLDVLEVVAPLKHINKLREFVTLKLPTGFPVKIEIPVLHTVTAKVTFQKFEFRDNIPAKMFEVPSHYWEDVRRFQDLXPGDGEAAPKAKAATGGPTGAATGVHVDLNRNASSPSIAEFD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ** . :.:: . . .. .: : * . : . : ... .. .* . :*:*..**..*:: *. *: * : :.:** ***********:*.*...:****:*****:** :*****:********* ** :** ** **** : .:* :*::**::: ***:*::******:**:******* *::**.* .*******:**.**: :***:**:* *:*.. **:*:*****: :**:::*** : *:***:***:*: :: :***:* *:*** **:** ::.* :* :: .::* ::**:*:.********.**: :*:**:*:::**.. :. * **.** .*. *::*.:*: ** **.*:*** * *:*:*.::**:*** :***.:: **:****:**:**:******* :***.*****::***: *:**.****:*. *:: .:* :*..* * ** ** ", "identical_positions": 238, "similar_positions": 160, "identity": "38.33%" }, { "cls_id": "homologset.agr.MGI:2139758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVT7-1", "uniprot_id": "D3ZVT7_RAT", "id": "D3ZVT7-1", "name": "Calcium-activated chloride channel regulator 2", "aln": "METRPLQPLKSHREMLPSVTQLSLRLTNLSNIGLCSLRPGTPWGQGPELVFLGAGLKLKENGYDGLLVAINPRVPEDLKLIRNIQEMITEASFYLFNATKRRVFFRSVQILIPATWTAHNYSRVKQESFDKANVLVTEQNGVPGEDPYTLQHRGCGQEGKYIHFTPNFLLNDELAAGYGSRGRVFVHEWAHLRWGVFDEYNSDKPFYVNGRNEIQVTRCSSDITGVF--VCEKGLCPHEDCIISKLFREGCTFLYNSTQSATGSIMFMQSLPSVVEFCNEGTHNREAPNLQNRVCSLRSTWDVITGSSDLNHSLPVLG--VELPAPPSFSLLQAGDRVVCLVIDVSRKMAEGDRLLRLQQAAELFLMQVVEAHTFVGIVTFDSKGEIRAPLQQINSDDDRKLLVSYLPTTVSTEAETNICAGVKKGFEVVEKQNGRADGSVMILVTSGAD-EHITNCLLTAMSSGSTIHSMALGSSAARRLGELSHVTGGLEFFIPDPFTSSRMTEAFSGISSGAGDIFQQSLQLESTCETVQPQHQLANTVTVDRAVGNDTFFLVMWQTGGPSEIVLLDPSGRKYNTGDFIINLPFRTASLKIPGTAKHGHWTYTLNNTHHSPQALKVTVASRASSLAVSPATVDAFVERDSTYFPQPVIIYANVRKGLYPILNATVMATVEPEAGDPVVLQLLDEGAGADVIKNDGIYSRYFFSFAVSGRYSLTVHVRHSPSTSTLAHSVPGNHAMYVPGYVTNDNIQMNAP-KRTGRRPVKERWDFSRVSSGGSFSVLGVPDGPHPDVFPPCRITDLAAMNVEEDVTLSWTAPGEDFDQGQTTSYEIRMSKSLQRIRDDFDNAILVNSSGLIPQHAGTRETFTFSPKLVTHELEHEPDEEAQETYIVYVALRAMDRSSLRSAVSNIVLVSMSLPPNSAPVVSRDDRILKGVLTIVGLITILCL-LLVVSHCTLNRKKRASRKENETKFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG22-1", "uniprot_id": "CLCA2_MOUSE", "id": "Q8BG22-1", "name": "Calcium-activated chloride channel regulator 2", "aln": "---------MTHRDSTGPVIGLKLVTLLFT--------------LSPELLFLGAGLKLKENGYDGLLVAINPRVPEDLKLITNIKEMITEASFYLFNATKRRVFFRNVQILVPATWTDHNYSRVRQESYDKANVIVAEQSEEHGDDPYTLQHRGCGQEGRYIHFTPSFLLNDELAAGYGARGRVFVHEWAHLRWGVFDEYNNDKPFYVNGRNEIQVTRCSSDITGVF--VCEKGLCPHEDCIISKIFREGCTFLYNSTQNATGSIMFMPSLPSVVEFCNESTHNQEAPNLQNQVCSLRSTWDVITASSDLNHSLPVHG--VGLPAPPTFSLLQAGDRVVCLVIDVSRKMAEGDRLLRLQQAAELYLMQVVEAHTFVGIVTFDSKGEIRASLQQIYSDDDRKLLVSYLPTAVSTDAETNICAGVKKGFEVVEERNGRADGSVLILVTSGAD-EHIANCLLTSMNSGSTIHSMALGSSAARKVGELSRLTGGLKFFIPDKFTSNGMTEAFVRISSGTGDIFQQSLQVESVCETVQPQHQLADTMTVDSAVGNDTLFLVTWQTGGPPEIALLDPSGRKYNTGDFIINLAFRTASLKIPGTAKHGHWTYTLNNTHHSPQALKVTVASRASSLAMSPATLEAFVERDSTYFPQPVIIYANVRKGLHPILNATVVATVEPEAGDPVVLQLLDGGAGADVIRNDGIYSRYFSSFAVSGSYSLTVHVRHSPSTSTLALPVPGNHAMYVPGYITNDNIQMNAP-KNLGHRPVKERWGFSRVSSGGSFSVLGVPDGPHPDMFPPCKITDLEAMKVEDDVVLSWTAPGEDFDQGQTTSYEIRMSRSLWNIRDDFDNAILVNSSELVPQHAGTRETFTFSPKLVTHELDHELAEDAQEPYIVYVALRAMDRSSLRSAVSNIALVSMSLPPNSSPVVSRDDLILKGVLTTVGLIAILCL-IMVVAHCIFNRKKRPSRKENETKFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQC9-1", "uniprot_id": "CLCA2_HUMAN", "id": "Q9UQC9-1", "name": "Calcium-activated chloride channel regulator 2", "aln": "---------MTQRSIAGPICNLKFVTLLVA--------------LSSELPFLGAGVQLQDNGYNGLLIAINPQVPENQNLISNIKEMITEASFYLFNATKRRVFFRNIKILIPATWKANNNSKIKQESYEKANVIVTDWYGAHGDDPYTLQYRGCGKEGKYIHFTPNFLLNDNLTAGYGSRGRVFVHEWAHLRWGVFDEYNNDKPFYINGQNQIKVTRCSSDITGIF--VCEKGPCPQENCIISKLFKEGCTFIYNSTQNATASIMFMQSLSSVVEFCNASTHNQEAPNLQNQMCSLRSAWDVITDSADFHHSFPMNG--TELPPPPTFSLVQAGDKVVCLVLDVSSKMAEADRLLQLQQAAEFYLMQIVEIHTFVGIASFDSKGEIRAQLHQINSNDDRKLLVSYLPTTVSAKTDISICSGLKKGFEVVEKLNGKAYGSVMILVTSGDD-KLLGNCLPTVLSSGSTIHSIALGSSAAPNLEELSRLTGGLKFFVPDISNSNSMIDAFSRISSGTGDIFQQHIQLESTGENVKPHHQLKNTVTVDNTVGNDTMFLVTWQASGPPEIILFDPDGRKYYTNNFITNLTFRTASLWIPGTAKPGHWTYTLNNTHHSLQALKVTVTSRASNSAVPPATVEAFVERDSLHFPHPVMIYANVKQGFYPILNATVTATVEPETGDPVTLRLLDDGAGADVIKNDGIYSRYFFSFAANGRYSLKVHVNHSPSISTPAHSIPGSHAMYVPGYTANGNIQMNAPRKSVGRNEEERKWGFSRVSSGGSFSVLGVPAGPHPDVFPPCKIIDLEAVKVEEELTLSWTAPGEDFDQGQATSYEIRMSKSLQNIQDDFNNAILVNTSKRNPQQAGIREIFTFSPQISTNGPEHQPNGETHESHRIYVAIRAMDRNSLQSAVSNIAQAPLFIPPNSDPVPARDYLILKGVLTAMGLIGIICL-IIVVTHHTLSRKKRADKKENGTKLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3APN3-1", "uniprot_id": "A0A8M3APN3_DANRE", "id": "A0A8M3APN3-1", "name": "", "aln": "---------MHLRSVFVLLWMLRLST--------------------------STGIKLDGNGYIDITIAISSKVPEDDKLIDKIKDMVTEGSVHLYKALDKKVYFKEVTILVPLNWNSKGFTKARTELFETGMIRIDNPHPAYGDEPYTNQYGECGAEGQYIHFTPNFLRDDKLIRLYGSRGKVLVHEWAHLRWGVYDEYSEKTPFYRSASGKIEATRCSKNIEGQLYDVTADPLQPCQNDPQTSLPTDGCRFIPNKYQSTDSSMMSLPSLDSVITFCRESEHNYEAPNLQNAKCSNKATWTVIFEDSVDKDALRSLKPMASTPPAPNFKVVQRMQRTVCLVLDVSGSMK-GSRILRLQQASAHFLQNIIEDQSSVALVTFSTDASTLSALTTIDKESTRENLVKLLPN--VAEGATNMCKGLNLGLQVLKTDNQDVLGDEIIFLTDGEATDTLSNCVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDVLSNQLLNGFSSLIMPTGNQTKDPVQIDSVG--IKTSDWFNGTVSVDQTIGTKTSFTITYETKLP-RISIQSPSGLTYSQTQMRHDEPAKTVTLKVPGTAQTGDWKYSILSP--TLQSLTVTATSQAARANVPPITVKAQMNQQFSDGSKPMIVFAEVVQNYKPLIKAEVWATLESESGTVHELQLLDNGAGADTFKDDGVYSRYFTRMKK-GRSSLKVRVKNKDGQARFTLQKRG-GAPYVPGYVVNGVVELNPP-KLSVSEELPEVGSFTRTATGESFEVS--LTSSKPPKFPPCKIIDLSAEIQEDAVLLSWTAPGEDLDEGSAKSYDIRWSFEVKDLLFNFSNAHVVNTSVISPQVFGSVEQHLFN-----------LSFPIQNGTILFFAIQSEDNEKLKSEMSNVASGLQIIP---NPNTGDLDLKLIFIAISVCLASVVVIGIFGITTWALTRKKLSDS--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 291, "similar_positions": 327, "identity": "29.94%" }, { "cls_id": "homologset.agr.MGI:2139793", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGS7-1", "uniprot_id": "CEPT1_MOUSE", "id": "Q8BGS7-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "MSGHRSTRKRCGDSHPESPVGFGHMSTTG----CVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEP-LMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID--VTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKLLPALCTVAGTIFSCTNYFRVIFTGGVGKN------GSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHPCLY----ILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEY-------IVLWIALIFSFFDLIRYCVSVCNQIASHLHIHVFRIKA-------------------------STAHSNHH-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXM5-1", "uniprot_id": "CEPT1_RAT", "id": "Q6AXM5-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "MSGHRSTRKRCGDSHPESPVGFGHMSTTG----CILNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEP-LMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID--VTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKLFPALCTVAGTIFSCTNYFRVIFTGGVGKN------GSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHPCLY----ILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEY-------IVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKT-------------------------STAHSNHH-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6K0-1", "uniprot_id": "CEPT1_HUMAN", "id": "Q9Y6K0-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "MSGHRSTRKRCGDSHPESPVGFGHMSTTG----CVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEP-LMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID--VTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKN------GSTIAGTSVLSPFLHIGSVITLAAMIYKKSAVQLFEKHPCLY----ILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEY-------IVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKV-------------------------STAHSNHH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRW3-1", "uniprot_id": "A0A8M9PRW3_DANRE", "id": "A0A8M9PRW3-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "MSGLAVAHGRRGGARERGRGVDSSCWFAP----GVLRRLFELPAPVLSRHQLKRLEEHRYSSSGRSLLEP-IMQQYWEWLVNRMPPWIAPNLITIVGLVTNIFTTLVLVYYCPTATEQAPLWAYLLCAVGLFVYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTSIAVQLGTHPDWMFFCCFAGMFMFYCAHWQTYVSGTLRFGIFD--VTESQICLALLQMFTAAVGPTIWNVTIPVINIQMKIIPALCTFIGVVFSCTNYFRVIFTGGVGKN------GSTIAGTSVLSPVLHIGSVIILAMMIYKKSAVQLFQKHPCLY----ILAFGFVSAKITNKLVVAHMTKSEMHLHDVAFLGPGLLFLDQYFNSFIDEY-------LVLWISLILSLFDLVRYCVSVCNEIASHLHICVFKIKP-------------------------QSAAGIQ--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8JLM0-1", "uniprot_id": "B8JLM0_DANRE", "id": "B8JLM0-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "MSSHKRPVRARSDSDSSSSAPRDPIVAATEEGPSLLTRLMELPVARLSRQQLKRLEEHRYSSEGRSLLEP-FMQGFWCWLVSKVPLWMAPNLITIVGLATNIVSTLILVYYCPTATEQAPTWAYLACALGLFIYQSLDAIDGKQARRTNSSTPLGELFDHGCDSLSTVFVVLGTCIAVQLGTYPDWMFFCCFVGIFMFYCAHWQTYVSGTLRFGIID--VTEVQIFIISMYLLAAIGGTAFWQSMIPVLNIQVKIIPALFTLLGAVFSCTNYFRVIFTGGMGKN------GSTIAGTSVLSPSFHIGVVITLALMIYKKSSVQLFEKHPCLY----VLAFGFVSAKLTNRLVVAHMTKSEMHRYDLAFTGPALLFLNQYFNSFINEY-------CLLWVALVLSAFDLVRYCVSVCNQIATHLNIRVFSIQPPSP-------------------SRVQTDGRNHH-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7Y4-1", "uniprot_id": "A0A0B4K7Y4_DROME", "id": "A0A0B4K7Y4-1", "name": "diacylglycerol cholinephosphotransferase", "aln": "-----------------------------------MALLAYRDKHILSAQQLRKLSEHKYSCFSVSLLDP-LLQPWWNWLVAQTPLWLAPNLITIVGLILNVVTTLILICYSPNGVEAPPRWTCLLCALGLFIYQSLDSIDGKQARRTNTSSPLGELFDHGCDSISTVFVALSACISCQLGHYPNWLFFQCFCAIALFYCAHWQTYVSGTMRFGRID--VTEAQFSIIAIHLVSAALGPEIWLTKLPHFNCESRFLPIYVACGVDLILALRYTKCILTEGCGKN------GSSVAGTSVLSPSIPLTLVVLPALMIAQKSPQNLFTEHASVY----IMAFGMVAAKVTNKLVIAHMTKAEMEYLDWSLLGPSLLFLNQYFNCIVPEI-------WLLWFTLIWGTQDLLRYCAQVCLEICQHLRIDLFRIPYTPKGATPHPATASVSSQSNFGSSADKNGGSAHRKSKSKPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17898-1", "uniprot_id": "CPT1_YEAST", "id": "P17898-1", "name": "Cholinephosphotransferase 1", "aln": "------------------------------------------MGFFIPQSSLGNLKLYKYQSDDRSFLSNHVLRPFWRKFATIFPLWMAPNLVTLLGFCFIIFNVLTTLYYDPYFDQESPRWTYFSYAIGLFLYQTFDACDGMHARRTGQQGPLGELFDHCIDSINTTLSMIPVCSMTGMG-YTYMTIFSQFAILCSFYLSTWEEYHTHKLYLAEFCGPVEGIIVLCISFIAVGIYGPQTIWHTKVAQFSWQDFVFDVETVHLMYAFCTGALIFNIVTAHTNVVRYYESQSTKSATPSKTAENISKAVNGLLPFFAYFSSIFTLVLIQPSFISLALILSIGFSVAFVVGRMIIAHLTMQPFPMVNFPFLIPTIQLVLYAFMVYVLDYQKGSIVSALVWMGLGLTLAIHGMFINDIIYDITTFLDIYALSIKH-------------------------PKEI-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22140-1", "uniprot_id": "EPT1_YEAST", "id": "P22140-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "------------------------------------------MGYFVPDSHIENLKSYKYQSEDRSLVSKYFLKPFWQRFCHIFPTWMAPNIITLSGFAFIVINVLTVFYYDPNLNTDTPRWTYFSYALGVFLYQTFDGCDGVHARRINQSGPLGELFDHSIDAINSTLSIFIFASETGMG-FSYNLMLSQFAMLTNFYLSTWEEYHTHTLYLSEFSGPVEGILIVCVSLILTGIYGKQVIWHTYLFTITVGDKVIDVDTLDIVFSLAVFGLVMNALSAKRNVDKYYRN-STSSAN-NITQIEQDSAIKGLLPFFAYYASIALLVWMQPSFITLSFILSVGFTGAFTVGRIIVCHLTKQSFPMFNAPMLIPLCQIVLYKICLSLWGIESNKIVFALSWLGFGLSLGVHIMFMNDIIHEFTEYLDVYALSIKR-------------------------SKLT-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .*. ::*.. . *::. .:: :* : * *:***::*: *: : ..: . * * .* *: : * *:*:**::*. ** :*** . . ******** *::.:.: : . :* . :: * ** : *: * : .: :. : * . : :* : :. .: : .: . .:. * . . : * *. :... :::.*: * ..::::.*:* : : .: * :: : : : *. : : .: :: .* : : * . ", "identical_positions": 54, "similar_positions": 115, "identity": "11.44%" }, { "cls_id": "homologset.agr.MGI:2139806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT90-1", "uniprot_id": "E9PT90_RAT", "id": "E9PT90-1", "name": "Spartin", "aln": "MNGARAFEMERGAENGEPPEMKIIKEAYEKAFMFVNKGLNTDELGQKEEAKTYYKQGIGHLLRGISIAAAEP---GHTGPAWEAARQMQQKMKETLQNVRTRLEILEKGLATSLRNDLQDVPKLYPEFPPKGTCKKSPEAES---APQHAEVDGSASAAGAGPSAAPSALPLPSPGCPAEAPPAYTPQAAEGHYTVSYGTDSGEFSSVGEDFYRNRSQPPPLETLGLDADELILIPNGVQIFFVNPAGEVSAPSYPGYLRIVRFLDNSLDTVLNRPPGFLQVCDWLYPLVPDRSPVLKCTVGAYMFPDTMLQAAGCFVGVVLSSELPED-DRELFEDLLRQMSDLRLQANWNREEEEEEEEEEDEFQIPGR---VKELPKEASGTDVRQSSSSGSSIDQGSKDARHKGKRGKKTKDSSSEEVNLRQIVPCEPSSEEKSKDLPEWSEKVAHNILSGASWVSWGLVKGAEFTGKAIQKGASKLRERIQPEEKPVEVSPAVTRGLYIAKQATGGAAKVSQFLVDGVCTVANCVGKELAPHVKKHGSKLVPESLKRDK-DGKSTLDGAMVVAASSVQGFSTVWQGLECAAKCIVNNVSAETVQTVRYKYGHNAGEATHNAVDSAINVGVTAYNIDNIGIKAMVKKTAKQTGHTLLEDYQIIESPQRESQGGATSTEGTRDVERKMEEEKKGAKKKDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1X6-1", "uniprot_id": "SPART_MOUSE", "id": "Q8R1X6-1", "name": "Spartin", "aln": "--------MEREPENGEPAEIKIIKEAYEKAFMFVNKGLNTDELGQKEEAKNYYKQGIGHLLRGISIAAAEP---GHTGPAWEAARQMQQKMKETLQNVRTRLEILEKGLATSLRNDLQDVPKLYPEFPPKDACKKSPEQESVSTAPQRAEVDGSASAACAGPSGAPSALPVPSPSCPAEAPPAYSPQAAEGHYTVSYGTDSGEFSSVGEDFYRNRSQPPPLETLGLDADELILIPNGVQIFFVNPAGEVSAPSYPGYLRIVRFLDNSLDTVLNRPPGFLQVCDWLYPLVPDRSPVLKCTVGAYMFPDTMLQAAGCFVGVVLSSELPED-DRELFEDLLRQMSDLRLQANWNREE--------DEFQIPGRSSHPSEPPKEASGTDVRQSSSSGSSIDQGSKDARHKGKRGKKTKDSS-EEVNLSQIVPCEPSSEEKSKELPEWSEKVAHNILSGASWVSWGLVKGAEFTGKAIQKGASKLRERIQPEEKPVEVSPAVTRGLYIAKQATGGAAKVSQLLVDGVCTVANCVGKELAPHVKKHGSKLVPESLKRDK-DGKSALDGAMVVAASSVQGFSTVWQGLECAAKCIVNNVSAETVQTVRYKYGHNAGEATHNAVDSAINVGLTAYNIDNIGIKAMVKKTAKQTGHTLLEDYQIVERPQRESQGGATSTEGRRDIGKQVEEEKPGAGKKDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N0X7-1", "uniprot_id": "SPART_HUMAN", "id": "Q8N0X7-1", "name": "Spartin", "aln": "--------MEQEPQNGEPAEIKIIREAYKKAFLFVNKGLNTDELGQKEEAKNYYKQGIGHLLRGISISSKES---EHTGPGWESARQMQQKMKETLQNVRTRLEILEKGLATSLQNDLQEVPKLYPEFPPKDMCEKLPEPQSFSSAPQHAEVNGNTSTPSAGAVAAPASLSLPSQSCPAEAPPAYTPQAAEGHYTVSYGTDSGEFSSVGEEFYRNHSQPPPLETLGLDADELILIPNGVQIFFVNPAGEVSAPSYPGYLRIVRFLDNSLDTVLNRPPGFLQVCDWLYPLVPDRSPVLKCTAGAYMFPDTMLQAAGCFVGVVLSSELPED-DRELFEDLLRQMSDLRLQANWNRAEEE------NEFQIPGRTRPSSDQLKEASGTDVKQ-------LDQGNKDVRHKGKRGKRAKDTSSEEVNLSHIVPCEPVPEEKPKELPEWSEKVAHNILSGASWVSWGLVKGAEITGKAIQKGASKLRERIQPEEKPVEVSPAVTKGLYIAKQATGGAAKVSQFLVDGVCTVANCVGKELAPHVKKHGSKLVPESLKKDK-DGKSPLDGAMVVAASSVQGFSTVWQGLECAAKCIVNNVSAETVQTVRYKYGYNAGEATHHAVDSAVNVGVTAYNINNIGIKAMVKKTATQTGHTLLEDYQIVDNSQRENQEGAANVNVRGEKDEQTKEVK-EAKKKDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN45-1", "uniprot_id": "SPART_DROME", "id": "Q9VN45-1", "name": "Protein spartin", "aln": "---------MAEEESEFLEAYAGIRTAYKAAMTQVDLAVSHEEQESPGQAIVAYELALRMIEDTFGIPVGLPNKIDTVQAEWNDACALIQKLKSAETELRYRLKVLRSQKQSIDDSAVEATEESRAEMDTK--------------RPPLLAENPSTQYGIANASGAPKTYRELAAGLRELLAVRDAKVLLD------------ELFRAQVKMYRIEASGSVTTISGSSTMSLVMCTVGGKWKYLS----------------------GIYFIQCSMPNEGTAGIWLYPLVPSITNCYQTEYGAFIFPDMECQQPGNAFGLMLTKEGQTSRTEDELEDLQQFFLDL------------------LEAVLAGTVVQLKSPTSQRAG----------------------------------------------------LASDTVSGSEQVSRHIVSAADFIASNLVRGAEKTGGFMLRSTPYIISKMTPASMDAQVPSSVQTSVEVAQKVTHAAAGMTGWIAGKVGTASMAVGRYLAPHIQEQGSKLLQKGFGYDTSEANSTMEGAMTIAAGAVEGVSTVFDGLETSAKILGSSLSENSVKIIEHKYGQQTGNLASGTFDTVGNVFVVSQNVNYITPKGIAKKMVKRTGEAVVSDY---KRDLRKSESHYINAGSLYPDLRALKE----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *: **: *: *: .:. :* . :* *: .: : :.*. . . . *: * : **:*.: ::* **::*.. : . :: . : .*: .* * : .:. *.. .** : : . . : : *: . .:** .:. . * .: .*:: . * : ::. .: : *. . *******. : : **::*** * .* .*::*:.* . .: :*** : : ** * :.* .. .: :* ..: . **:*:::*:*.*.::: .**:*** ** : :.:. : .:: * . .:*..:* .: :*::.* .** :: :.. * *.: .**: ****::::****: :.: *. :.:*.::***.:**.:*:*.***::*** :** : ..:* ::*: :.:*** ::*: : :.*:. ** :.: *:: * *.:.** ..:**.:::.** . *:.: .. . :* ", "identical_positions": 125, "similar_positions": 215, "identity": "18.04%" }, { "cls_id": "homologset.agr.MGI:2139810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFM3-1", "uniprot_id": "D3ZFM3_RAT", "id": "D3ZFM3-1", "name": "", "aln": "MIPPEPPQPQLQPPPPPAPPNHVVTTIENLPAEGSGC-VSLSTSSRAGMRQRIRKVLNREMLISVALGQVLSLLVCGIGLTSKYLAEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGFIDLEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEESIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRNPSGPVSDLPSTAQVEPSVTYTSLGQETEEEPHVRVA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGK5-1", "uniprot_id": "S35F1_MOUSE", "id": "Q8BGK5-1", "name": "Solute carrier family 35 member F1", "aln": "MIPPEPPQPQLQPPPPPAPPNHVVTTIENLPAEGSGG-VSLSASSRASMRQRIRKVLNREMLISVALGQVLSLLVCGIGLTSKYLAEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEESIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRNPSGPVVDLPSTAQVEPSVTYTSLGQETEEEPHVRVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T1Q4-1", "uniprot_id": "S35F1_HUMAN", "id": "Q5T1Q4-1", "name": "Solute carrier family 35 member F1", "aln": "MIPPEQPQQQLQPPSP-APPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQRIRKVLNREMLISVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEPSVTYTSLGQETEEEPHVRVA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ** *****.* ******************* ***:****.:*************************:**********:***************************************************:********************:******************************************************************************** ****************************************************************************************************************************************** ***:**************************", "identical_positions": 392, "similar_positions": 9, "identity": "95.84%" }, { "cls_id": "homologset.agr.MGI:2139883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96DT7-1", "uniprot_id": "ZBT10_HUMAN", "id": "Q96DT7-1", "name": "Zinc finger and BTB domain-containing protein 10", "aln": "MSFSEMNR---RTLAFRGGGLVTASGGGSTNNNAGGEASAWPPQPQPRQPPPPAPPALQPPNGRGADEEVELEGLEPQDLEASAGPAAGAAEEAKELLLPQDAGGPTSLGGGAGGPLLAERNRRTLAFRGGGGGGLGNNGSSRGRPETSVWPLRHFNGRGPATVDLELDALEGKELMQDGASLSDSTEDEEEGASLGDGSGAEGGSCSSSRRSGGDGGDEVEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTSWLKDFPWLRYSKDTGLMSCGWCQKTPADGGSVDLPPVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQ-----------------------------ESEIPSEEG---YCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVNRDGLSSS-RDQKIASFWATRNLTNLASNVKIE----NDGCNVDEGQIENYQMNDSSWVQDGSPEMAENESEGQTKVFIWN-------NMGSQGIQETGKTRRKNQTTKRFIYNIPPNNETNLEDCSVMQPPVAYPEEN-TLLIKEEP--DLDGALLSGPDGDRNVNANLLAEAGTSQDGGDAG-TSHDFKYGLMPGPSNDFKYGLIPGTSNDFKYGLIPGASNDFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGVDQGQDTEFPRDEEYEENEVGEADEELVDDGEDQNDPSRWDESGEVCMSLDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q8X5-1", "uniprot_id": "E9Q8X5_MOUSE", "id": "E9Q8X5-1", "name": "", "aln": "MSFSEMNR---RTLAFRGGGLVTG-GGGPTNNNAGGEASSWPPQPQPRLPAPPAP---QQPNGRGADEEMELEGLEPQDSEAAAG-AAAAEDVKELLLLPQDTGGPSLLGGGAGGPLLAERNRRTLAFRGGGGGGLGNNGSSRGRPETSAWPLRHFNGRGPAAVDPELDALEGKEWMQDGASLSYSTE--EEGASPGDGSGAEGGSCSSSRRSGGDGGDEAEGSGVGAGEGETVQHFPLARPKSLLQKLQCSFQTSWLKDFPWLRYSKDTGLMFCGWCQKIPEDGGGVDLTQVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQ-----------------------------ESEIPSEEG---YCDFNSRPNENSYCYQLLRQLDEQRKKDILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCVSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVSRDSLPSSSREQKIASFWATRNLTNLASNIKTE----NEGCDVDEGQVENYQMNDSNWIRDGSPELAENESQGKTKVFIWN-------NMTS---QETGKARRKNQTTKRFVYNIPPNSETKVEDCSVMQPPAAYPEESKALLIKEEP--DLDGALLSGPDGDRTMNTNLLAEACSGQDAGDAG-ASHDFKYGLMPGTSSDFKYGLLPSTSNDFKFGLLPGASNDFKYGLLPESWPTQETWENGDSSLIMNKLKCPHCSYVAKYRRTLKRHLLIHSGVRSFKCEICGKMFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIKHGSRRYGVCMDCVDKSQPGGQEVVNQGQDTEFPRDEEYEENEGGEPDEELAEDGQDENDAPRWDESGGVYVSG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTY8-1", "uniprot_id": "ZBT10_RAT", "id": "Q9WTY8-1", "name": "Zinc finger and BTB domain-containing protein 10", "aln": "MGPGRRGNGIGGPGAPRLGGLRRGGRRGGRQGVAAPLGHGRPRLAGRRRGGPPAS------------------GKEPSDSGLPRGRRRGSRQQWQQSRPPGDLG---------VAPQAFQWAR--AGGRGSGAGRAGGEGVDAGR---GVPELQHRGGGG------------------------------EPGRWQWGGRRQR----SSSRRSGGEGGEEAEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTSWLKDFPWLRYSNDTGLMFCGWCQTTPEDVGSVDLPQVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQVLGSQACVTVDGSAVDKPDASEGCLLVGNESEIPSEEG---YCDFNSRPNENSYCYQLLRQLDEQRKKDILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCVSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVSRDGLTSS-RDQKIASFWATRNLTNLASNIKIE----NDGCNVDEGQIENYQMNDSNWVQDGSPELAENESQGKTKVFIWN-------NMAS---QETGKARRKNQTTKRFVYNIPPNSETIVEDCSVLQPPVAYPEENKALLIKEEPVSDLDGALLSGPDGDRTMNTNLLAEACSSQDAGDAAGASHDFKYGLMPGTSSDFKYGLLPSTSNDFKYGLLPGAPNDFKYGLLPESWPTQEPWENGDSSLIMNKLKCPHCSYVAKYRRTLKRHLLIHSGVRSFKCEICGKMFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIKHGSRRYGVCMDCVDKSQPGGQESIDQGQDTEFPRDEEYEENEGVEPDEELAEDGQDQSDAPRWDEPGGAYVSG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5PMB0-1", "uniprot_id": "A5PMB0_DANRE", "id": "A5PMB0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MLKTEG---------------------------------------------------CKKATGNGVNREDGSTGEAEETAARKPLLEMRPQTLLQK-HSLFQACWLEEFPWLRFSHETGLMSCSWCHNIATN---------NSDELVKGSRNYKRALLLRHHLSSEHGRNDPTKQ-----------------------------EMERPEDAESPEVEDYRNKPNENSYCYQLLQELDKQRKSGILCDVNIVVSGQVFRAHKNILVAGSRYFKTLYCLTKSESCDQTTITHLDVAAVQGFSVILDFLYSGNLLLTSQNAIEVMSVASYLQMTEVVQSCRAFIKDALNISIKQEAPDSVVVDYNKRRTVAKDCQGAD---KKPSNFWATSILSKLSIKASVQGQVKDEPSDVEVSGGEGCALGSSGWGGENSSESTETEPQGPGPVFVWNPDPSNGATVKQEVRSEPGSGRRKKQAAKRFVYNIPPEPEEGFDEGMFIQPSASYTREDFSYLS---------------------------------ENAGEAP---------------------------------------------------------EN-----ALNKLKCPHCNYIAKHRRTLKRHLIIHSGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVECAD-SHQGTQEGLEGMQDLEFARDEDFDEAGEGDEDMEAEGEEPNEIDQSHCEGDAGATPVKD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .::: *:* :. :** * * : : : **::*:** :. **:.**::*****:*::**** *.**:. . : . *** :*:****::******:*:** ::.. * * * *.: *:..:***********::*::***..*****.*****::*:***********:******.::.** :*.. ****:******************:**********:*******:****:** ***********.***:*******:*:.* :* :. :* :.**** *::*: : . : :: .:*: . *. :..*.* :.*.* :*.*.:* **:** .: . .*.*. ***:*::***:*****: * .:: .:**..:*..*. : * ::.*:* ** :********.*:**:********:**:*****.*:****:*************************************:*********::*.* *: * ** :: ** **.***:::* : * * : :: * .: : . . ", "identical_positions": 304, "similar_positions": 162, "identity": "32.97%" }, { "cls_id": "homologset.agr.MGI:2139916", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFY8-1", "uniprot_id": "A0ABK0LFY8_RAT", "id": "A0ABK0LFY8-1", "name": "", "aln": "MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLAILAKKELPLAKSGVPQVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYLREQLVKISDFYHM----ASSTGDG----------------------------------------PVPVPP----------------------------------------------------------------EVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLSWILDVLEKIR---PVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSD-SPNLLAAHSPHMIIGANNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWN-YSTNENKIANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWA---NQNKDNQEVAP-------NDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEVEAERCGE-SEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPSLSDPNSE-CEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTAST-GLRSPAGENSDEHYSKDHEM----KMEEHAVMAHMGLGSGTTNIFDEVDKSDFKSDFGSEFPIFSPMPGESCENIN-PSLSRRMSGNGEKLGKREKPRELIFPSNYDLLRHLQYATHFPIPLDE----SSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTESGVGDEGQKARKNKQEVFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFG---DLFSSACSKVKQTIYNNVMPANSN-LRWDPDFMMDFIENPS-ARSINYSMLGKV---LNDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACG-----DADAEPGARMTCRLLLHLFR---APQACFFPQA---TGKPFPG----IRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTLKNEDFSMRGLRRDGSAEDAWATSQNSKPYGKSIS-----------------------------------IETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASSSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQ---DDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSTASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHFLLYHTHTMPKPRSYYLEPLPLPPEEEEEEPTSPVSQEPERKSAELSDHGKSAADEEKKTKGRKRKTKSSSRIDEYQQTN-IYRLPPNYSPMSSQMMHHTQPALWGYNLVSQPQQPSFFLQNQSLNAGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMLQPPSLHAVTSQQQLLQMKLLQQQQQQQQQQQQQQQQQRLLRQAQTR----PFQQGQPGDQAALFTAQARPSPQLPQYPGLQQQAQTMPQG---------------YTMYGTQMPLQQAAQQQPGGVVLSPSYSSRAYPAAH-------------------SSPALMERLRQLQQQPG-GYVQQQASPYLQPVAGSQR-----------------LNHQALQQSPLVGGAIDAVL---------------------------------TPAHPNLPSVPLAQDPMRPRQQQVRQQQR-------------------------------LLQ-----MQQPQQA--PQPQQP---------------SQPQSQALGLQAMQP---------------------------------QQPLFPRQG------------LQQTQQQQQTAALVRQLQKQLSSNQ---------------------------PQQGVTPCAHPSHF--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQM9-1", "uniprot_id": "MD12L_MOUSE", "id": "Q8BQM9-1", "name": "Mediator of RNA polymerase II transcription subunit 12-like protein", "aln": "MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLAILAK-----------KVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYLREQLVKISDFYHM----ASSTGDG----------------------------------------PVPVPP----------------------------------------------------------------EVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIR---PVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSD-SPNLLAAHSPHMIIGTNNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWN-YSTNENKISNPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWA---NQNKDNQEVAP-------NDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGE-SEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPALSDPNSE-CEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTAST-GLRSPAGENSDEHYSKDHDM----KME-----------------------------------IFSPMPGESCENIN-PSLSRRLSVNGEKLLKREKPRELIFPSNYDLLRHLQYATHFPIPLDE----SSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKGTTESGVGDEGQKARKTKQEVFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFG---DLFSSACSKVKQTIYNNVMPANSN-LRWDPDFMMDFIENPS-ARSINYSMLGKI---LNDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACG-----DADAEPGARMTCRLLLHLFR---APQACFFPQG---TGKPFPG----IRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTMKNEDFGMRGLRRDGNAEDAWATSQNSKSYGKSIS-----------------------------------IETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASNSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQ---DDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSSASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRKVIKYEEQQHFLLYHTHTMPKPRSYYLEPLPLPPEEEEEELTSPVSQEPERKSAELSDQGKATADEEKKTKGRKRKTKSSSRIDEYQQTN-LYRVPPNYSPMSSQMTHHPQPALWGYNLVSQPQQPSFFLQNPSLNPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMLQPPSLHAVTSQQQLLQMKLLQQQQQQQQQQQQQQQ--RLLRQAQTR----PFQQGQPGDQAALFTAQARPSPQLPQYPGLQQ-AQTMPQG---------------YTMYGTQMPLQQAAQQQPGGVVLSPSYNSRAYPAAH-------------------SSPALMERLRQLQQQPS-GYVQQQASPYLQPVAGSQR-----------------LNHQALQQSPLVGGGIDAVL---------------------------------TPAHPNLPSVPLPQDPMRPRQQQVRQQQR-------------------------------LLQVWGREMQQPQQA--PQPQQP---------------SQTQSQALGLQAMQP---------------------------------QQPLFPRQG------------LQQTQQQQQTAALVRQLQKQLSSNQ---------------------------PQQGVTPCAHPSHF--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YW9-1", "uniprot_id": "MD12L_HUMAN", "id": "Q86YW9-1", "name": "Mediator of RNA polymerase II transcription subunit 12-like protein", "aln": "MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLSILAK-----------KVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYLREQLAKISDFYHM----ASSTGDG----------------------------------------PVPVPP----------------------------------------------------------------EVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIR---PMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSD-SPNLLAAHSPHMMIGPNNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWN-YSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWA---NQNKDNQEVAP-------NDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGE-SEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSE-CEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTAST-RPRSPVGENADEHYSKDHDV----KME-----------------------------------IFSPMPGESCENAN-TSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDE----SSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGVGDEGQKARKNKQETFPTLETVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFG---DLFSSACSKVKQTIYNNVMPANSN-LRWDPDFMMDFIENPS-ARSINYSMLGKI---LSDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACG-----DADAEPGARMTCRLLLHLFR---APQACFLPQA---TGKPFPG----IRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNPKSCGKSIS-----------------------------------IETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLNN-SSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQ---DDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKK--QGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHPMPKPRSYYLQPLPLPPEEEEEEPTSPVSQEPERKSAELSDQGKTTTDEEKKTKGRKRKTKSSSRVDEYPQSN-IYRVPPNYSPISSQMMHHPQSTLWGYNLVGQPQQPGFFLQNQSLTPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHAITSQQQLIQMKLLQQQQQQ-----------RLLRQAQTR----PFQQGQPGDQAALFAAQARPSPQLPQYPGLQQ-AQTMPQG---------------YTMYGTQMPLQQTSQQQAGSVVLSPSYNSRAYPAAH-------------------SNPVLMERLRQIQQQPS-GYVQQQASPYLQPLTGSQR-----------------LNHQALQQSPLVGGGIDAVL---------------------------------TSAHPNLPSVPLPQDPMRPRQPQVRQQQR-------------------------------LLQMQQPQQPQPQQP--PQPQQS---------------SQSQSQTLGLQAMQP---------------------------------QQPLFPRQG------------LQQTQQQQQTAALVRQLQKQLSSNQ---------------------------PQQGVTPYGHPSHF--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2QCI8-1", "uniprot_id": "MED12_DANRE", "id": "Q2QCI8-1", "name": "Mediator of RNA polymerase II transcription subunit 12", "aln": "MAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNSSKISSNFSSIIAEKLRCNTFPDTGKRKPQVNQKDNFWLVTARSQSSINNWFTDLAGTKPLTQLAK-----------KVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAITENKMKKRHVIDPCIEWTPIITKYLWEQLQKVAEFYRQ----SPSQGCGS---------------------------------------PLPAPPA---------------------------------------------------------------EVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIR---PGEDELLRLLLPLLLQYSGEFVQSAYLSRRLAYFCTRRLNLLLSDGSIGPGPGGHQAHGISAQQGNALPPTPTSQPAGGNQPQTPFTDFYICPQHRPVVFGLSCMLQSIVLCCPSALVWH-YSLTDSR-NKTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRWSFDKCQETTAGFTISRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGS---GQSKDGHEMSP-------DDDAVVTLLCEWAVSCKRSGPHRAMVVAKLLEKRQTEIEAERCGE-SEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVLTEPGNE-SERVEFSNLVLLFYELIRHDVFSHNIYMCTLISRGDLASNSHLPRPRSPSDEPSDESERKDQDAGSSVKMEDTGMSESMEIDHNSSAN---------------FDEMFSPP--MHCESKGSPSPEKQAQEQESKSTAKDKGMDPAFPLVYEQPRHIQYATHFPIPQEE----SASHECNQRLVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAETG-GEEGQKRKRSKPEAFPTAEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQLLNELSLVEAELLLKSSNLAGSYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFG---EIFSEFCSKVKNSIYYNIDPSDSN-MLWDQMFMIDAITNPT-AHNLNHSMLGKITNELNDSPANRYSFVCNVLMDVCVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNGNCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLVRCVAIPSLLNAACS-----EQDSEPGARLTCRILLHLFR---TPQRNPCPQDGTKSDKSIVG----IRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELKGSGFSHPAG---------LDDIGEDDMGSK---KSGGRNVS-----------------------------------IETASLVVYAKYVLKSICHQEWVGERCLKS---LSEDSSALQDPVLVNIQAQRLLQLICYPHRQLDSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNN-------ELYSLLENIAKATIEVFQKSAEMNSSNPSWNGSAVS----GSSVSNSNSASKLKPVLSSSERSGVWLVAPLIGKLPTSVQGHVLKAAGEELEKGQHLGPSSRKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQ---DDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSESLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFE------KEGLQVSTKQKISPWDVFEGLKHSAPLSWGWFGTIRVDRKVTKFEEQQRLLLYHTHIKPKQRSYYLAPLNLP--QEEEEPLTPVPPEPDKK-LDTAKVEKSVSN--VPTKKKKKKPASTVKQEDYKPHNTVMQYAPGMTPDLPLSMGQTN---MSYRMGYQAPMN-MYAQNQPLPPGGPGLEP-----PFRPRVPMNKMPPRPNYTMPN----MQTAGMGNLMGMEKQYQMNYKP-----------MPNMAQGQ----MLRHQLQG-HNHLIGQQIRQVTPNPQYSSMQP-AQNIPQG---------------YTSYGSHMGMQPHPSQTPG--MVPNSYGNQGFQTGHPA-----------------TNPTMVDSIRQMQQRPG-YVHQQAPAAYGHTIQSTQR-----------------FPHQSMQQTPMMHGLAQSHLG-------------------------------VQGIHPNMRPNQMMEQQQQQQQQQQQQQQQQQQVHQQQQHIRQGPVFRPQQQQQVQQQVQQQVQQQQVQQQQVQQQ--VQPQQVQQQQVQQQQQQQVSAAQPPAQALGMQALPP---------------------------------QQPMFQRQG------------MQQTQQQQQTAALVRQLQQQLSSTQ---------------------------PAQ-----NNSSYY--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW47-1", "uniprot_id": "MED12_DROME", "id": "Q9VW47-1", "name": "Mediator of RNA polymerase II transcription subunit 12", "aln": "---MLSMLQEKRPLKRTRLGPPDIYPQDAKQREDELTPTNVKHGFTTTPPLS-DEFGTAHNSNVNASKVSAFFSGVLAKKEELMTLPDTGRKKQQINCKDNFWPVSPRRKCTVDAWFKDLAGNKPLLSLAK-----------RAPSFNKKEEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKKRSIYDPAAEWTGNMIKFMKELLPKLQEYYQQNHDKSSSNGTTSGSLTAAGNGPASNGSTGTSSINSVTGSSASTNVIPVPSMASPLPPIHSPANGQQAAPGGGVNAGSVMPTTGSLGGVVGGPGSSVVGGAAGAGAAVPPGSTISGIGSQFEDSRNALKYWKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQASFDEPLKKLVLSFALQYMHDFVQSERLCRKMAYIVSKKLAQLLNT--------------VVEQQTIKELDEPKLQ---QDPYELALQEQMSCPHHRDIVLYLSTILQIITIECPTALVWSGIAAHRAPSSLLGSPLDHLPLAPSVLPMPTRCPRTNHEIRRQLRAAESDIVLRTQHAEQRWFAAKWLSAGKNQYTS-VLATLDHLDTHCFDRMEHNNSIDTLYAQIFPSPTVSRRREEDQVEPRPPYEPKQDKDTVRILCEWAVSGQRWGEHRAMVVAILLDKRQIDVTSTPADQQSSDKDDKDSLASGAGLIDGLPVFQHVLMHFLDHDAPVLDEHVSSPQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESVLVIKSGTTATKTSPPPPAPPPT-TTHGFDDDGFGGGLDFKHN---------------------EFDDSNVDDDLDKLVQNIKEKGQQHEAPDSPKIGPPGDGETNPGGSISRHYVYTKHFPIPQDDPSMSSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEIGKLFTKKFSIDVAAAGHVKKHSRNE----FNFEATTSKCQQMAYFDQHVVTAQCAANVLEQLNGFALGNNNYLPVQEHVAFLFDLMELALNIYSLLELCDSLLKELPEVEHQLQLKKSNLVRSYTTSLALYIVSILRRYHSCLLLSPEQTLSVFEGVCRTIRHVSNPSECTSAERCIIAYLSDLHESCVLLQGKEQSTEYYQQLQCIKRFKDIFNTPEQLDLPPQGYNPLLLQELFMAPRRGGKLDPHWLGTL----HESPANVYSFVSNALIAVCR-ETDNERLNDVALACAELTASCNVLSEEWIYALQSLCSGSK--SPRYPHLGGQVDIGQLKTHNALAVFVCILVARHCFSLADFVSKFALPTLARSVSAGGAELSVDAEAGARLTCHLVLKLFKTLEIPQPGMYSVSTSPNPLHAVGNDFSIRLSCDRHLLVGAHKTIPIAAVLAVLKAILIVVDNAALKTPLASGSGTSSGGLGGAFGSGKRSGFNTPVHPGSTPKSNEQRPADLSQILGTSDLQLGSSLTSEPEALQQPSVGGMEQISLLEFAQAVLKQICAQEHVLERCLKNAEQLCD---MIIDEMLTAKQAQRVLHMICYPEPEFN-IISELDQRSMIVRILENLGQWTLRISWLDLQLMYRQSLSNN-----AELNVWLDTVARAAIDVFHMEEVVLP---------------GAVKATHKP------------KPSTWLVAPLIAKLTPAVQGRILRVAGQVLESMNYFSKVSKSDCNSSGSGDEREKSNSCHSSNSYGLGGVPARNKKMPLDYQPFLGLILTCLKGQDEYKENLLVSLYAQLSQCLQSFAELDTIGGIDEPQAREEILDALQLRFSLVGGMFEAIQKNSTPTTDWAILLAQLVCQGVVDLSCNRELFTTVVDMLATLVHSTLVSD-----------DERHYMNLMKKLKKEIGEKNNASIRVIRQLLPLYKQPTEVIACEHSG--MDTKGNKICDID------KKQLRISDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLVKPSSYYYEPLPLPP-EDIEPVPEKICIKDEMKADTPSSVDQSPSAVVGGTGRGRGKGTTTRKRKPKNPKTPPVVNTQQQQPQLAQQPQQPQN--VQQQQLQQQQQQQQHMQQQHMQQQQMQPNQMG-QMPMNMPMNMQQFAPNPN-NMMQQNAMLQQQQQQQMQQMGNNPMQQQLNVGGGNGQPNPQMNFMQQGPGGGGAGPQGMPGQQQQWHNAPQQQQPPQPYHNQYAPHQQNMQSNRIERPPLNANSKQALSQMLRQRQPFQQQAQQGPGGGFNPMQQQPQASQQQPGPQQQMNPNQMRQQQMNPQQNPQSVAAFNAMQQQPQQNAQQQQMNPNQQQQQQFMRGGNMRPGMAPNQMNQMNMGGQGMSQNPMMQQQIPQNMVGMVNPNANQMMQSGGAQGGNGVGVGVGVGVGGAGNNPNMGMGGMPQQGMIQQQPQQQPQQQVQFQNFQNQYQQQQQQGMQQQGGGAGVGVGVGMAPNQQQQQQANMMGNFNPQMQQGNRNNPDFMAAAAVAQQQQQQQQQQRVVPGGMMAGNRNQYMNQAPNVTMSTMMGPGPGGVVGQVPPYARQQSAGGGKPGVLNTQQQFQQQQQQQQQLRHQMMQLQGMGGGAGGGMGAGPQQGGGAVGGGAGGGMVPQQQSMNQQQTPNLVAQLQRQNMMGQQQYQPPPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:*****.******:****.**:*****. ***:**.. *..: **.*:*:* .*.**:.: **.::*:* . *: ***::* *:* ***:* *:.* :.::. **.****.*** *** :.* :.***::* *.: .* : *::*:**::.** :::* * *** ** *** ::: * * *: ::*: :.* * . * ** : . *:* *:* .:*: .*:::.:*:::*:*.*:*: ::*:* . :: * :*:*.: *** :**** *.*::**: :::* **. : :: * . : .: : *.:* :* ** :** :.: **:**** : ***** * :*** **** . *:::* :: *.:* * : .* ** * .: . * ** **: ** *.*:: : .**:::** :** : .: :: .:: * :*. .* :******* :* * ****.** **:*** :: : ..: *. *:* *::*.: *****.**::*** :** * : .. ::.** *** ** :********: ** ******** : .. :. :: : .. :. : . : . : . ** *:.***** :: * * *.*** ::*:****:*** :* :**::*:* *::.:* : : . . . :* :.: . * :* * :::**** **:* : *****:..** * . :**: .*: ::***** :*** .*:::. .**:**. ** :* **.*.*. ****.*.: **::********:*.*:** .**:*: .:: **::*:*.****:*** **: ** *:.* . * * : *: . : :: :: : : * . .:: **.: :..** ****.*.*: ** . * *:**:. .:**** * ** **: .*::**..*: : .: **:.:*. *::**.*:.**:**:*: * *.* .*:*:* :... . *:*.***:**:::*:**: ** . . * ** *******..::::* :.**:*****:::: * . . . .. . : . :. . :* .* :*: **: ** ** * *:***. *. : * :* ***::*::****. : .: **. * ***:*: ***:* * *:**** :*. .: *: *:.:*:*:*:**: . : *: .. . : ..*******.:*..:***::*:.**: **. :::. *:.: : :::** * *. ****.*:********* :*.**.** *:.* : .: * *: :*:: : :**:**:.******:::*:.: **:**:** ::: .*.**: *.******:***..*::.**.:* ::* ****:***:**:*::.. *: :****** **. :**:** * :*******..:: . *::* **::* **::** *:.***** ***:::::*: .:** :: * **** * *** ** ** :: * : : : * :. :: : * : * :: : . . . * . :.: . * . *: : : * . :.:: . . * : :: * : : * : * : : . * : *.: .. : :* ..* .* . . . :. .* : :. :**:* ** . : * : *.:.*.*:: : :**: : :: :* * : **: : * : :** :* * * : * * * : ** ** ***** :*: **.. * * :.. ", "identical_positions": 689, "similar_positions": 621, "identity": "25.93%" }, { "cls_id": "homologset.agr.MGI:2139971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A307-1", "uniprot_id": "D4A307_RAT", "id": "D4A307-1", "name": "Protein arginine N-methyltransferase 6", "aln": "MSL--SKKRKLESG-VG--GAGGEGAEEENGGEQEAAPPRPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAQEVVRLNGLEDRVHILPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPDSAELFVAPISDQMLEWRLGFWSQVKQHYGVDMSCMESFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAIWFQVTFPGGDSEKPLVLSTSPFHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSRDNPRRLRVLLRYKVGDHEEKTKDFAMED------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZB1-1", "uniprot_id": "ANM6_MOUSE", "id": "Q6NZB1-1", "name": "Protein arginine N-methyltransferase 6", "aln": "MSL--SKKRKLESGDSGGAGAGGEGAEEENGGEQEAAPPRPRRTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELPERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPISDQMLEWRLGFWSQVKQHYGVDMSCMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPFHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILLRYKVGDHEEKTKDFAMED------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LA8-1", "uniprot_id": "ANM6_HUMAN", "id": "Q96LA8-1", "name": "Protein arginine N-methyltransferase 6", "aln": "MSQ--PKKRKLESG-GG--GEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWG4-1", "uniprot_id": "ANM6_DANRE", "id": "Q6NWG4-1", "name": "Protein arginine N-methyltransferase 6", "aln": "MSQHATKKRKLDRS--------------------------------TEDYMYFDSYSDVTIHEEMIADTVRTNTYRMGIFKNSKSIEGKVVLDVGAGTGVLSLFCAQAGARKVYAVEASSIADQAVKIVKLNQMEDRIEVIKSTLETIELAEKVDVIVSEWMGYALLHESMLNSVIFARDKWLKPGGLILPSRADLYIAPINDVVVEGRLDFWSTVKGQYGVDMSCMTDFARKCIMN-KDITVNPVTVEDVLSHPCKFAELDLNTVTLEQLRD--VNGSFSCVCFGSSSIHAFCVWFTVTFP--AEEKALVLSTSPFKAETHWKQAVLYLDDAVDVMQDTKVEGEISLYPSEENSRHICIRVDYVIGEQKKHSKSFSIPDQYLEVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .*****: . .* :*::.****::******* ***::**:**::* ::.**.*********:**:********:*******:* :** ::*::* :***:.:: ..:**:**.*:**.********.*******.**:.** **** ***:** *:*::***.* ::* **.*** ** :*******: .** :*:*. .:*.*: :: ****::* :**:*:* . *** : *.* * * *:**:.:*.*.:** **** .**.********:. ******:***::.* * ***.:.***:* ** :*.*:: : : * :*::::::*.*:: * ", "identical_positions": 190, "similar_positions": 107, "identity": "49.22%" }, { "cls_id": "homologset.agr.MGI:2140018", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZD5-1", "uniprot_id": "D3ZZD5_RAT", "id": "D3ZZD5-1", "name": "", "aln": "MDPEISVEEQNPLELDLNEITRELLFLDQWRGVF---RLGSSHATPQNHDGSHRFAEETGGGSRMSPSQGQRQLSSSGVCSIPRLAVISSKLHGFPISPAMATMLQRSLFGNTNQVLGSDWRKAHFKFHDPFSDLAFALQVEKGGAQSIQMAVQGSIIKYLLFARE-GKDCSLHSLCNLSQREQEQALAAVLAGILWAAGTAQKAIVCFVTKD-IHSTSTLDCSRDNFIERLQLFEFSEKEATEKFVYDHLQRFQGEGSHGVILFLYSLVLSRTFERLQKDLDSTTTHLLQSQAGGILCRQAVLNMILTGRASPNVFNGYE----EGRSEGALHGVLTRSDVGYLQWSKDTA--EGDQLSQVGSRLKTPVFPIWLCNINGNYSILFCTNRQLLSDWKMERVFDLHFYSGQ----------PSQQRPVHLTIDTHSHQWERGHHEDKRGSGRRFS----------------------------------------------SLEMLIRTKWREATINWNGTSPFF--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1W2P7H6-1", "uniprot_id": "A0A1W2P7H6_MOUSE", "id": "A0A1W2P7H6-1", "name": "", "aln": "MDPEVSVQEQNPLELDLNEITRKLLFLDQWRGVF---RLGSSLTTPQNHDGSHTSAEETGEGSRVFPSPGQEQLPSSMVCSIPRLPGISSKLHGFPIAPAIATMLKRSLFGNTNQVLGGDWRKAHFKFHDPFSDLAFALQVEKGGAQSIQMAVQGSIIKYLLFTRE-GKDCSLQSLCNLSQREQEQALAAMLAGILWAAGEAQKAIVCFDTKD-IHSTSTLDYSSNNFIERLQLFEFSEKEATEKFVYDHLQCFKGEGSHGVILFLYSLVLSRTFERLQKDLDTTTTHLLHSQAGGVSCRQAVLNLILTGRASPNVFNGYE----EGKSEQSLHGILARSDIGYLQWNKDTS--EGDQLSQVGSMLKTPTFPIWLCNINGNYSILFCTNRQLLSDWKMERVFDLHFYSGQ----------PSQKKPVHLTIDTHSHHWEGEHHEDKHGSGRRFS----------------------------------------------SLEMVIRTKWREATINWNGTIPFF--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MYZ0-1", "uniprot_id": "MIY4B_HUMAN", "id": "A8MYZ0-1", "name": "Inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B", "aln": "MDMEVLGQEQSSEQLDLEEISRKISFLDKWREIFSYHRLGTNNSTPQNHEGNHTSADENEDGTGLSQPKGQGHLPSSGLCSIPNPSIISSKLGGFPISLAMATKLRQILFGNTVHVFSYNWKKAYFRFHDPSSELAFTLEVGKGGARSIQMAVQGSIIKYLLFTRK-GKDCNLGNLCEISKKEQEQALAAALAGILWAAGAAQKATICLVTED-IYVASTPDYSVDNFTERLQLFEFLEKEAAEKFIYDHLLCFRGEGSHGVILFLYSLIFSRTFERLQMDLDVTTTQLLQPNAGGFLCRQAVLNMILTGRASPNVFNGCE----EGKSQETLHGVLTRSDVGYLQWGKDAS--EDDRLSQVGSMLKTPKLPIWLCNINGNYSILFCTNRQLLSDWKMERLFDLYFYSGQ----------PSQKKLVRLTIDTHSHHWERDQQEEKHGPRRRFS----------------------------------------------PVEMAIRTKWSEATINWNGTVPFF--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTG6-1", "uniprot_id": "Q9VTG6_DROME", "id": "Q9VTG6-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY", "aln": "------------------------------------------------------------------------------------MNKEFITQGGTPITAELATDLRNLVFGTAAIPMRAEWLQTSFVFGAPKEELAYGLRSPRNATRGLLSVVQGFVLKYLLFARKTSRVASLTDPLLATADMQREALFCALLEILRTISDKGKVTMVLPSEDEVFVDHSACYFHDSVTEKLYVFTLSPNDELEYFLKRNFKYFTEEETPGTLLFLYSAVLTRSMGKVRTDLDSAKSTPLTSSN-HEEGSLMIVTLLLTGRATPYIHNGVVNVGDESSYAVPQYGVLKRCMIGLLLWDIESASAAVNQSRQPGSRLKTPNYPIWITSCTGHFGVIFNKNPDLLRNYHAESRFDVNYYSCSGHQILMTIDNRTYNEQALVMLERQPITPESTSMSGKEDGGGATSPTTVSGGGGAAAGGGVGGASGGVGGAASGASGGNDVVAKEESTLNTPLQRLIRTKWEEATISFHVQPSMLSYLFSTTQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * **: :** *:. :**.: : :* :: * * * .:**: *. :..::.: .*** ::*****:*: .: ..* . : *.:** . * ** : . *. : : ::* :. : :.. *:* :* : :: * *: :: * * : *.:***** :::*:: ::: *** :.: * .. ::.::*****:* :.** *. . :*:* *. :* * *. ::: :: * ** **** ***: . .*::.::* .* :** ::: * **: :** . : :. . : :: :. * . *.. * .:: ***** ****.:: .:: ", "identical_positions": 98, "similar_positions": 131, "identity": "18.42%" }, { "cls_id": "homologset.agr.MGI:2140050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUT9-1", "uniprot_id": "D3ZUT9_RAT", "id": "D3ZUT9-1", "name": "", "aln": "MELQKGKG-TVAAASSGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGG-DVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRSMLREKFPEFCSSPS----------PPVEASFPEASGILGSTRGYQESFFLYSQVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDD------------EEDLNSKGKKREFRFHPIKETVVEE---PVDVTPYLDQLDESLRDKVLQLQKGSDTEAQ---CEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRG-EVLPEEVTEES-LEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLG---------DLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETVIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPD-DQFTTSILRHWCMKHDELLAEHIKALLIKNN--SLPRKRQ-SLRSSSSKLAQLTLEQILEHLDNLRLNLAN-TKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRR--KAALSSPRSRKNAAQPPNAEEES---GSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPD0-1", "uniprot_id": "INT3_MOUSE", "id": "Q7TPD0-1", "name": "Integrator complex subunit 3", "aln": "MELQKGKG-TVAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGG-DVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRSMLREKFPEFCSSPS----------PPVE-------------------------VKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDD------------EEDLNSKGKKREFRFHPIKETVVEE---PVDVTPYLDQLDESLRDKVLQLQKGSDTEAQ---CEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRG-EVLPEEVTEES-LEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLG---------DLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPD-DQFTTSILRHWCMKHDELLAEHIKALLIKNN--SLPRKRQ-SLRSSSSKLAQLTLEQILEHLDNLRLNLAN-TKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRR--KAALSSPRSRKNATQPPNAEEES---GSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68E01-1", "uniprot_id": "INT3_HUMAN", "id": "Q68E01-1", "name": "Integrator complex subunit 3", "aln": "MELQKGKGAAAAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGLPQHEEICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPS----------PPVE-------------------------VKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDD------------EEDLNSKGKKREFRFHPIKETVVEE---PVDITPYLDQLDESLRDKVLQLQKGSDTEAQ---CEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRG-EVLPEEITEES-LEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLG---------DLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPD-DQFTTSILRHWCMKHDELLAEHIKSLLIKNN--SLPRKRQ-SLRSSSSKLAQLTLEQILEHLDNLRLNLTN-TKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRR--KAALSSPRSRKNATQPPNAEEES---GSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXC9-1", "uniprot_id": "INT3_DANRE", "id": "Q1LXC9-1", "name": "Integrator complex subunit 3", "aln": "MEPSPAKG----------------------KAQGRLLVSTSLDAKDELEERLERCMSITTSITNGLSEREANDALTAHVCKGPQQHEEVCLGLFTLLLTEPPQAQRCYRDLTLVNRDGMNVVLMKINQILMEKFLKLQDVCRTQLVWLVRELVKSGVIGADGVLMTLMKQIAGG-DISSKNLWLAENVLDILVDQREWVLKSGMLVAMSLYTYLRLIVD-HGTTSLLPLRQREVDFCIGLLRERFMECFIIGRDLVRLLQNVARIPEMELVWRDLLHSPQTLSPQFTGILQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEGQVRQGVFNSLNFIMEKRVLAHLAPLFDNPKLDRELRSMLRERFPEFCSSPS----------PPTE-------------------------VKMEESVPLEMDNHVLDKEDGCYDNTDATFSDD------------EEELNNKGKKREFRFHQLKETYIDE---PSDITPFVDQLDEALKERVLQLQKGSDTETH---CEVMQEIVDLILEEDFDSEQMSTLASCLAELFKSHFRG-DVLPEEITEES-LEESVCKPVCLIFRNLCQMQEDNSGFSVLLDLLAELYQKQPKIGYHLLYYLKASKAASGKMSLYESFAQATALG---------DLHTCLMMDMKACQEDDVRLLCYLTPSIYSEFPDETLRSGELLNMIVAVIDSAQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPYHQE-DQFTTSILRHWTAKHDDLLGEHIKALLIKNN--NMPRKRQ-SLRSSSSKLAQLTLEQMLEHLDSLRLSLSN-TKNNFFSQTPILQALQHVQASCDEAHKMRFSDLFSLAEEYEDSS-KPPKSRR--KAPASSPRSRKGAAPQPCNEEES---VSSSASEEEDSKPKASKRKRKGS-AVGSDSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLS8-1", "uniprot_id": "INT3_DROME", "id": "Q7PLS8-1", "name": "Integrator complex subunit 3", "aln": "MEQQQSKN---------------------NAHVSKLFICTAVDCKDDIEEKFERSFVTLQMQISGLSDKEMHDMLSQAVCK-EKQHEEISIGFLYIMLTDPSMASKTYRDVTLVSRDGMNGIVTNLTFLVAEKYTKLTEVARRQLIWLLREFVKHQVLSVENVIWNCLRQAGGG-DVSSRNLFLIESLLDIFIEFRTWLETNPFLVQSTVYSFVRLIED-HANPALLSLRQKEVKFTISLIRERFHDIIPLGRDFVRLLQNVARIPEFEQLWRDILFNPKMLHQTFNGIWQLLHIRTSRRFLQCRLLPEMERKISFLASSVKFGNQKRYQDWFQDKYFATPESHSLRSDLIRFIINVIHPTNDMLCSDIIPRWAIIGWLISSCTNPIASANAKLSLFYDWLFFDPAKDNIMNIEPGILVMYHSIRNHPFVSSTLLDFLCRITKNFFVKHEDKIRIGVYNSLKLILEKQVIPNLQPLFESPKLDRELRNLIRDNFREFLSPPANHGQLLFTSLHPVQG-----------------------HILKKESDQRILHCENMDLHETGLINISGTIDEDKKILLVPTDQEIESVFSDETAENLRRVHNIEDNTDDDDDLPLSEVRLKEKPKVELAEAIAESFDAFVTKRNSYTWEAFLKDFRPLPASAFEEFQLNYVISNTVLILRETLPQQNIFSESKTEEKHLAKSISYPLYGLFRFLYENDEKSK--KPFQTLLSEICEGIPEIGYLLLYFMKIYCKLQTRKNSQQSYQFKTTIYRQICDAADEKIGNCLLRDLDLLEKENTNIFLWLLPDIYREFKSIATNNTDLLRITLRCIDAKNVRDILYSIAQGKLTIFKQDGLIDCIRQSLEFETYEQFCLWQIVQAHDVPLRCIQDILPELEAGSHPEALSHFLLLLKNEEPTNEIIRLMLSRESKSKGDPFVTSALRFWCQRYEEKLSEIIASLLTSKYPSSSPNKRKRPPKGISVSTSTPSADQVLNHLEHYRRSCRHGTGTGLYVHDMMQRALQSAYSHSNDSTKKQFCDLFALAAEEDTTVGRRGGSGRGRKQPGSKKDVNNHGTSKKNPEMVKTIYSSDDNSSEEDWSKSKILQTAKRRKKANNDSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . .*. .:*::.*::*.**::**::**.: *:*::* :* *. *** ****:.:*:: ::**:*. *.: ***::**.***** :: ::. :: **: ** :..* **:**:**:** *:..:.* . ::* .** *::::*::* *.:***: : * *: .. :*: ::*:::*** * *... * .***:**.* *.*:**** : : :***:************:* :*:*::..*: * *.** *** ****:** *** *:** *: *::* *:**:********* :*::*.:*:***.****:* .*:**:*::*.***:*********:::**. :*::****:********.* **.******.****:**:: ** :::*****:*** :*: *.::* **:.**: *:**:*:.:* ***:.****:*** ::*:.* ** *.*: *.: : :*. :. . * .: * ..::.:* *. :..: :. *.* :::. :: * . . :: . * : : : .. *: : *.: : . : . *:. *:. : * ::: : :::.*. ***. * :*: *: :** * : :*... . : **:*: : *:*** ***::: : . :*: * : .: .**: *:. ::::..:: * *.** ** . : .. :**.: : **: :::::: : *:*.:*::*.::: : ***::**:**:. **:. **.:**. : ** .*: .****** :** *:.*:*::*:::::*** : . * *.** **.* :::: *.* * :** .: . *.**: . :. * . : : :*:*:**: * . : * .:: : : :*** . : .::: * :*.***:** * : : : * * * . *. .: .: * . *.. *.*** . . :. * ...***", "identical_positions": 368, "similar_positions": 376, "identity": "32.95%" }, { "cls_id": "homologset.agr.MGI:2140076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALQ1-1", "uniprot_id": "A0A8I6ALQ1_RAT", "id": "A0A8I6ALQ1-1", "name": "", "aln": "MSTILLNLDFGEPS-KKAFGGNAKHQRFVKKRRFLEQKGFLSKKNQPPSKVSKLNSEPPKKGETSRVDSISKILSCLKKKKEAAASKRDSEQSKDKKAS-SWLTPAPSKKTDSVVAKIDLLGEFQSALPKPKRRTQKKGSKK-PLKKKIATENSTQAQSKDKGSNKKPLKKNAVQNSTQAQPEDKCPKVPQSLPRKMVAIDCEMVGTGPKGRVSSLARCSIVNYNGDVLYDEYIRPPCYIVDYRTRWSGIRKCHMVNATPFKTARSQILKILSGKVVVGHAIHNDYKALQYFHPKSLTRDTSQIPLLNRKADCPENVTLSLKRLTKKLLSRDIQTGLSGHSSVEDAQATLELYKLVEVEWEQHLAQNPPEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6G4U4-1", "uniprot_id": "A0A8I6G4U4_RAT", "id": "A0A8I6G4U4-1", "name": "", "aln": "MSTILLNLDFGEPS-KKAFGGNAKHQRFVKKRRFLEQKGFLSKKNQPPSKVSKLNSEPPKKGETSRVDSISKILSCLKKKKEAAASKRDSEQSKDKKASLSWLTPAPSKKTDSVVAKIDLLGELQSALPKPKRRTQKKGSKK-PLKKKIATENSTQTQSKDKGSNRKPLKKNAVQNSTQAQPEDKCPKVPQSLPRKMVAIDCEMVGTGPKGRVSSLAHCSIVNYNGDVLYDEYICPPCYIVDYRTRWSGIRKCHMVNATPFKTARSQILKILSGKVVVGHAIHNDYKALQYFHPKSLTRDTSQIPLLNRKADCPENVTLSLKHLTKKLLSRDIQTGLSGHSSVEDAQATLELYKLVEVE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AXU3-1", "uniprot_id": "I20L2_RAT", "id": "Q6AXU3-1", "name": "Interferon-stimulated 20 kDa exonuclease-like 2", "aln": "MSTILLNLDFGEPS-KKAFGGNAKHQRFVKKRRFLEQKGFLSKKNQPPSKVSKLNSEPPKKGETSRVDSISKILSCLKKKKEAAASKRDSEQSKDKKASLSWLTPAPSKKTDSVVAKIDLLGEFQSALPKPKRRTQKKGSKK-PLKKKIATENSTQTQSKDKGSNKKPLKKNAVQNSTQAQPEDKCPKVPQSLPRKMVAIDCEMVGTGPKGRVSSLARCSIVNYNGDVLYDEYIRPPCYIVDYRTRWSGIRKCHMVNATPFKTARSQILKILSGKVVVGHAIHNDYKALQYFHPKSLTRDTSQIPLLNRKADCPENVTLSLKHLTKKLLSRDIQTGLSGHSSVEDAQATLELYKLVEVEWEQHLAQNPPEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1G5-1", "uniprot_id": "I20L2_MOUSE", "id": "Q3U1G5-1", "name": "Interferon-stimulated 20 kDa exonuclease-like 2", "aln": "MSTILLNLDFGQPS-KKAFGGNAKHQRFVKKRRFLEQKGFLNKKNQPPNKVSKLNSEPPKKGETSRVDGILKILPCPKKK-EAAASKRDSERSKDKKAPLSWLTPAPSKKTASVVSKIDLLGEFQSALPKTKS-TQKKGSKKKSLKKKIATENSTQAQSKDKGSKKKPLKKNAVPNSTQARSEDKCPTVPQNLPGKMVAIDCEMVGTGPKGRVSSLARCSIVNYNGDVLYDEYVLPPCYIVNYRTRWSGIRKCHMVNATPFKTARSQILKILSGKVVIGHAIHNDYKALQYFHPKSLTRDTSRIPLLNRKADCPENVTLSLKHLTKKLLSRDIQVGNTGHSSVEDAQATMELYKLVEVEWEQHLAQNPPEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9L3-1", "uniprot_id": "I20L2_HUMAN", "id": "Q9H9L3-1", "name": "Interferon-stimulated 20 kDa exonuclease-like 2", "aln": "MSTLLLNLDFGEPPPKKALEGNAKHRNFVKKRRLLERRGFLSKKNQPPSKAPKLHSEPSKKGETPTVDGTWKTPSFPKKK--TAASSNGSGQPLDKKAAVSWLTPAPSKKADSVAAKVDLLGEFQSALPKINSHPTRSQKKS----------------SQKKSSKKNHPQKNAPQNSTQAHSENKCSGASQKLPRKMVAIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTRWSGIRKQHMVNATPFKIARGQILKILTGKIVVGHAIHNDFKALQYFHPKSLTRDTSHIPPLNRKADCPENATMSLKHLTKKLLNRDIQVGKSGHSSVEDAQATMELYKLVEVEWEEHLARNPPTD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*******:*. ***: *****:.******:**::***.******.*..**:***.*****. **. * . *** :***...* :. ****. **********: **.:*:*****:****** : . :. .*. *:.*.*::: :*** *****:.*:**. ..*.** ****************:*****:***************: ***:**:********** ********* **.******:**:*:*******:****************:** **********.*:***:******.****.* :***********:********* ", "identical_positions": 244, "similar_positions": 68, "identity": "65.77%" }, { "cls_id": "homologset.agr.MGI:2140077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86UD5-1", "uniprot_id": "SL9B2_HUMAN", "id": "Q86UD5-1", "name": "Sodium/hydrogen exchanger 9B2", "aln": "----------------------------------------------------------------------------------------------------------MGDEDKRITYEDS-------EPSTGMNYTPSMHQEAQEETVMKLK------------------------GIDANEP--TEGSILLK---SSEKKLQETPTEANHVQRLRQMLACP-------------------PHGLLDRVITNVTIIVLLWAVVWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLPSLLGMLLAGFLIRNIPVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSE-------------KAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPETVGLCVATVGIAVLIRILTTFLMVCFAGFNLKEKIFISFAWLPKATVQAAIGSVALDTARSH--GEKQLEDYGMDVLTVAFLSILITAPIGSLLIGLLGPRLLQKVEHQN-------------------KDEEVQGETSVQV-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BKR2-1", "uniprot_id": "SL9B2_MOUSE", "id": "Q5BKR2-1", "name": "Sodium/hydrogen exchanger 9B2", "aln": "----------------------------------------------------------------------------------------------------------MEDEDKTAECQHS-------KPPTGITHEAPPHHELQEERVMSLR------------------------GTDRSEP--TEGSNLLT---SGEKKPQDSPTEPNGLQSLRRFLACP-------------------PRGCLARVITNGTMVVLLWAMVWSVTGPECLPGGNLFGIIILFYCSITGGKLFGLIKFPTLPPLPPLLGMLLAGFLLRNIPVINDSVRIQHKWSSSLRSIALSVILVRAGLGLDSKALRKLKGVCVRLAMGPCIVEACASAILSHFLMGLPWQWGFILGFVVGAVSPAVVVPSMLLLQEGGYGVGKGIPTLLMAAGSFDDILAITGFNTCLGVAFSTGSTVFNIFRGILEVVIGVAAGSFLGFFIQYFPSRDQDNLVWKRAFLVLGFAVLAVFSSVYFSFPGSGGLCTLVMAFLAGMRWTDK-------------KSEVEKVIAVTWDVFQPLLFGLIGAEVSIVSLRAETVGLCVATLSIAVLIRILTTFLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSH--GEKQLEDYGMDVLTVAFLAILITAPIGSLLIGLLGPRVLQKSEHR--------------------TEEEVQGETSAHIQRKPEDSITEA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B6Y3-1", "uniprot_id": "A0A8M2B6Y3_DANRE", "id": "A0A8M2B6Y3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MEQKCSAMEDVQSRPHSAHSLYSQRTEDATSALGNHAEHHLTVSQTVLVVPK------------------------RPESPNPSMTEETIYVPRPVSAVDACTNTDPPYECCPWLRRLCPCP-------------------PRGMLAAIITKVTMAAVLFGVVWSITEKECLPGGNLFGIVTLFICSVAGGKLFGRIRLPRLPPVPPLLGMLLAGFILRNIPVVTDAVYIDVRWSSSLRNIALGVILVKAGLELDSKALKKLKAVCLRLSMFPLIFEAATMAVMSYLILGLPWIWGFILGFVLGAVTPAVVVPSMLLLHRQGYGLEQGIPTLLMAACSVDDIIAITCFTTCLGIAFATGSVWLNVLRGPLEVLGGAVTGVALGFFLHYFPSRDQRNLVLKRSFLVLGLSVFALFGSNVAGIPGAGGLCTLVLAFVAGIGWGRA-------------KASVEAVVERFWLVFQPLLFGLIGAEIVISSLELTTVFLGIAALFIGLTVRLLVTFIVVLRAGFNLKEKIFVTLAWMPKATVQAAIGSTALDMARSK--QDLELQKYGMDVLTVAVLSIIITAPIGALLISLLGPRLLQKPKNP--------------------EWAVSQGALSASGTPVTYESAL--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM74-1", "uniprot_id": "Q9VM74_DROME", "id": "Q9VM74-1", "name": "", "aln": "MFSSHKKMTATGEPEAREDPSVGGAPATITTPTTIIAPTPIPVPSDVPMPNSNGSGNGAGNHRSTIVIESQPKRRVSIISDPPMIGGNGGL----GTGYDNPAYEQNPRRKISQTSTHSHTDIGPARRKSILKDTAPHDNESDRVSTHSYENYRQNALDVLNAKYNGHQMGHNGGGSSNGGANYVEESWMYNFCLKCRGEEPSASWEPPFWQKIFPYPLCP-------------------TFRTVSRLISIILIGVLIWVTAFVIIGDSAAPGGQLFGLVVLTVAANFGGYLISLTTLP------RLIGMLLVGILFQNVGWADIDGDFS-KVTAHLRKFALTIILTRAGLEMEPEAFKKVYKTILKLGIIPWCVEAVVMAVMSHFLLDLPWIWAFLLGSIIAAVSPAVVVPCLFRLRTKGYGVAKGIPTLVVAVAGVDDALSVAIFGIISTVMFSDKGLAYQIAQAPVCILGGLGFGVVWGSLARIFPEKGDAYVVPLRTLLLFTGGLMAIYGSEELGFEGAGPLAVVFSAFVSNLFWCKDGW--------DVEDNPVSTAFEIFWMIFEPILFGLTGATIKIRELDSHTVSIGAACIFTGAILRILTTAGIAFGDRLNTKEKFFVGLSWMAKATVQAALGPVALKHLGDD--ATEEERNWANIVQTICVFSIVLTAPLGAIMISVTGTKLLTKTKQPQDLSGWRRSHRPSIRDISIIDEEEEREDPEIPEDKETHDNTLNNAHIPSISYTYNT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K6G5-1", "uniprot_id": "A0A0B4K6G5_DROME", "id": "A0A0B4K6G5-1", "name": "", "aln": "MSSDSDILDVVAGSEGPPLQAFRSSNPFEDSYQMSSCQQDFERDRDANLTPLHMLRRASETVTASILEPEKEHLLGDKPQVPPRAHGSTAPSAIEAKRSRQQPNQWQLQQQQQPSSNNNNTKRALAPGDNMTQGAAPQDSQGDILPTRPLHTKLDIQKIPEDEAGADATQNAATIILTPTSLNLTNTTTQNVAANNAGNSSTTTSTNTNYGPGSVSGYPTPNATPGDEYKGPKWWLYIRSHWVNTSELVALLAIFLGLWAMGWVLLPEYSQPPTVIMRIAFLFVGAQISGILVTFVHLP------DMLGMLFFGVLYANLGLANFEGYQK--FELFLREMALINIMLLAGLGLDGDAFKRLWFMILRLTLLPTIVEVAAIAGLANLTLSMPWLWGIALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISVIFSTTSLTQQVLQGPIGIGIGLVFGYLYGSMLQYLPSRNATYANGLRFVLTILGGTIAVMGSRVIGYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIGKEINFNVLQGHVIGYGALLVLVGSLFRLAFAYLSTYGGNLSRKERAYITISGFPKATVQAALGPVALDMARAASVASPEQLALAGNLLIISVLAIIFTAPLGAILMLRLAPYWLKHGDAV---------------------EAVDSPTTPIAPTLGSTNSSKGT------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . . . . . .: : . : * ::: : :: : : . * :: : * : .* *. :* ::***: *.: *: . **.:** *: *** :: .*:::: ::* : * .*. . * :: :.:** *.: ** :: **:* ***. :: *: *: .*: **: * :* ::: * : *: . :: :. : : * * * : : :*.:. * .* : . :*: .* . .:* * : **:: : * * . * .::*: *.* * : : * .: : . .*: : . :. **: :: :: :.*******:*..**. : . : :..::*::***:*:::: .. * : . ", "identical_positions": 83, "similar_positions": 150, "identity": "10.99%" }, { "cls_id": "homologset.agr.MGI:2140103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC44-1", "uniprot_id": "B1WC44_RAT", "id": "B1WC44-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMTESVD--------RSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGTVPCRYKSSQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSIVR--DLKRNAGAGVISKKHTLGEVWIQKTSEMDT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMKSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDREDMDT--------------DDERQYQDFLEDLEEDETIRKNVNIYRDS--TVPV-ESDTD---DEGAPRISLAEMLEDLRISQ--DATGEEGASMMS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99L48-1", "uniprot_id": "NMD3_MOUSE", "id": "Q99L48-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMAESIE--------HSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGIVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMSQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSTVR--DLKRSAGAGVISKKHTLGEVWIQKTSEMNT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEYVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDRENMDT--------------DDERQYQDFLEDLEEDEAIRKHVNIYRDA--TIPV-ESDTD---DEGAPRISLAEMLEDLHISQ--DATGEEGASMMS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96D46-1", "uniprot_id": "NMD3_HUMAN", "id": "Q96D46-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMAESTD--------RSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSAIHLIDPNTLQVADIDGSTFWSHPFNSLCHPKQLEEFIVMECSIVQ--DIKRAAGAGMISKKHTLGEVWVQKTSEMNT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARERENMDT--------------DDERQYQDFLEDLEEDEAIRKNVNIYRDS--AIPV-ESDTD---DEGAPRISLAEMLEDLHISQ--DATGEEGASMLT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BLF0-1", "uniprot_id": "NMD3_DANRE", "id": "Q5BLF0-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMQAPPS--------SSHGNILCCTCGVPIPPNP-ANMCVSCLRTQVDISEGIPKQVTIHFCRQCERYLQPPGSWVQCALESRELLALCLKKLKASMSKVRLIDAGFLWTEPHSKRIKIKLTIQKEVMNGAILQQVFTVEFVVQGQMCEDCHRVEAKDFWKAVVQVRQKTVHKKTFYYLEQLILKHKLHQNTVRIKEIHEGIDFYYATKQHAQKMVDFLQCTVPCRSKASQRLISHDVHSNTYNYKSTFSVEIVPVCKDNVVCLSPRLAQSLGNMGQVCVCVRVTSSIHLIDPNTLQIAEVDGSTFWRHPFNSLCSPRQLEEFIIMDIDIIR--DQRLGAGAGLKSNKHTLAEVWVQKTSEMDS-SHQYHCRTFMGHLLNIGDLVLGFDFANANINDEFLNKMNPQHVPDVVLIKKSYDRMKRARKRVWKLKEMDREKDAADT--------------DDERQYTEFLEDLEEDEMLRKNINIFRDAS-KIPVEESDTD---DDGAPRISLAEMLEDLSLS---DATGGEGADMMTD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46050-1", "uniprot_id": "O46050_DROME", "id": "O46050-1", "name": "60S ribosomal export protein NMD3", "aln": "MDHEYVGVSPLGAADGKGAGSNAVILCCECGVAIQPNP-ANMCVTCLRNHVDITENIPKQAVLHFCRNCERYLQPPNEWIQAALESRELLAICLKKLKG-LKEVKLVDAGFIWTEQHSKRIKVKLTVHGEIIGGTMLQQVFVVEFTVQNQMCNDCHRTEAKDFWRCLVQVRQRAENKKTFYYLEQLILKHKAHENTLGIKPEHGGLDFFYANDNHARRMVDFLLTMVPGKVTTSKRLISHDIHSNNYNYKYNWSVEIAPVSKDSAVCLSKKLRHQLGNLSPLVLVNRVSSSIHLIDPLTAQIAELTSQVYFRAPFEAVCNPKQLVEYVVMDIDVIMEKDRKTYPGQGQVSFKHALCDIWVVRASELGINDNPIHTRSHLGHLLKVGDSVMGYNTGEANINDLEFDKLSSDEIPDVILVRKHYDRQTRLSQRVWKIKHLA--AEATDE--------------RSKYDYHEFLDDLEENEDIRGQVNIYRDTN-KTIPIEVQAA---GGDVPQITLEEMLEDMTLECADDEMGEEGGADDTEPQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38861-1", "uniprot_id": "NMD3_YEAST", "id": "P38861-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEFTPIDPHQH------QNAATLLCCNCGTPIDGSTGLVMCYDCIKLTVDITQGIPREANISFCRNCERFLQPPGQWIRAELESRELLAICLRRLKG-LTKVRLVDASFIWTEPHSRRIRIKLTVQGEAMTNTIIQQTFEVEYIVIAMQCPDCARSYTTNTWRATVQIRQKVPHKRTFLFLEQLILKHNAHVDTISISEAKDGLDFFYAQKNHAVKMIDFLNAVVPIKHKKSEELISQDTHTGASTYKFSYSVEIVPICKDDLVVLPKKLAKSMGNISQFVLCSKISNTVQFMDPTTLQTADLSPSVYWRAPFNALADVTQLVEFIVLDVDSTG-----------ISRGNRVLADITVARTSDLGVNDQVYYVRSHLGGICHAGDSVMGYFIANSNYNSDLFDGLNIDYVPDVVLVKKLYQRKSK-KSRHWKLKRMAKEHKDIDASLDYNSRAQKQEMERAEKDYELFLQELEEDAELRQSVNLYKNREANVPPEEHEMDEDEDEDAPQINIDELLDELDEMT--LEDGVENTPVESQQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . :*** **..* .. :* *:: ***::.:*::. : **::*:*::*** *::. ********:**:::*. :.:*:*:**.*:*** **:*:::***:: * : .:::**.* *:: * * ** * :.: *:. :*:**:. :*:** :*******: * :*: *. : *:**:*: .:** :*::** ** : . *:.***:* *:. .** .:****.*:.**. * *. :* :.:**:. . : :::.:::::** * * *:: ..:: **:::. ** *::::: . ::.* :: : ::*::. .: . *:.:* : : ** *:*: .:.* *. .: :. : :***:*::* *:* .: * **:*.: . * : :* **::***: :* :*:::: * : . ..*:*.: *:*::: * *. : ", "identical_positions": 151, "similar_positions": 191, "identity": "27.81%" }, { "cls_id": "homologset.agr.MGI:2140113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62805-1", "uniprot_id": "H4_HUMAN", "id": "P62805-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62804-1", "uniprot_id": "H4_RAT", "id": "P62804-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84040-1", "uniprot_id": "H4_DROME", "id": "P84040-1", "name": "Histone H4", "aln": "MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P62806-1", "uniprot_id": "H4_MOUSE", "id": "P62806-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02309-1", "uniprot_id": "H4_YEAST", "id": "P02309-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*******************:********************************.*.*** ***.****:*************::******************", "identical_positions": 94, "similar_positions": 8, "identity": "91.26%" }, { "cls_id": "homologset.agr.MGI:2140151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2QC27-1", "uniprot_id": "A0A0G2QC27_RAT", "id": "A0A0G2QC27-1", "name": "Nucleolar protein 6", "aln": "--------------MGPAPAGQQQRGSTSTGEPEVMELALEGLGKE--KASSRKRAQAEAPAEGLPQPVKLSREE---LYKEPTNEELNRLRETEILFHSSLLRLQVEELLKEVRLSEKKKERIDAFLKEVIKRIQKVPPVPEAELTDQSWLPAGVRVPL-----HQVPYAVKGSFRFLPPSQITIVGSYPLGTCMRP--DINVDVVLTMPREILQDKDGLNQRYFRKRALYLTHLAYHLARDP------LFGSVRFSYPSGCHLKPSLLLRPHGKDE----------RLVTVRLYPCPPLDFFRPCRLLPTKNNVRSAWYRGQSCPDYASLEPPTPHYNTWILQDTALEAHMHLLSSVLASAQGLKDGVALLKVWLRQRELDK------GLGGFNGFLISMLVAFLVS------KRKIHTTMSGYQVLRSVLQFLATTDLTINGISFSLSSDPSLPSVADFHQLFA----VVFVDPSGRLNLCADVTASTYNQVQYEAELSMALLDSKADDGFQLLLMTPKPMIQAFDHVVHLRPLSRLQAACHQLKLWPELQDNGGDYVSAALG-----PLTNILVQGLGCRLHLLAHSRP-PVPEWAINQ------DPPKHKDAGTLTLGLLFRPEGLTSVIDLGPEA---DRPEAAEFRQFWGSRSELRRFQDGAIREAVVWEAE--SLSEKRLIPHQVVTHLLALHADIPDTCIHYVGGFLDALIQG-------------PRETSSTGEEALALAVRCYDDLSRLLWGLEDLPLTVSAVQGAHPVLRYTEVFPPAPVRPAYSFYNRHQELASLLPRLDKPCPAYVEPMTVVCHLEGSGQWPQDAEAVQRVRAAFQLRLAEVLTQQHRLQCRATATHTDVLK------------GGFVFRIRVAYQR-EPQILKVVRSPEGMISMRDTPASLRLERDTRLLPLLTSALHGLQQQYPAFSGVARLAKRWVRAQLLGEGFT-DESLDLVAASLFLHPEPFTPPSVPQVGFLRFLYLISTFDWKNNPLIVNLN-----------------------------SELTAEEQVEIRSSFLAARTQLP---VMVIVTPQDRRSS--VWTQD-GPSAQILQQLVSLAAEALPILEKQLMDPRGPGD-IRTVFRPPFDIYDVLIHLTPRHIP-RHRQAVDPPAASFCRGLVT-EPGPSS-LMPVLGYDPPQLYLAQLREAFGDLALFFYDQHGGEVIG------VLWKP-SSFQPQPFKASSLKGRMVVSRGGELVTVPNIEAILEDFAVLGEGLVQAVEARSERWTV------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R5K4-1", "uniprot_id": "NOL6_MOUSE", "id": "Q8R5K4-1", "name": "Nucleolar protein 6", "aln": "---MPSAGERPAVKMGPAPAGEQHR--RATEDPEVMELAFEGMDKE--KAPSRKRARTEPPAEGLLQPVNLSREE---LYKEPTNEELNRLRETEILFHSTLLRLQVEELLKEVRLSEKKKERIDNFLKEVTKRIQKVPPVPEAELTDQSWLPAGVRVPL-----HQVPYAVKGSFRFRPPSQITVVGSYLLDTCMRP--DINVDVAVTMPREILQDKDGLNQRYFRKRALYLAHLAYHLAQDP------LFSSVRFSYMSGCHLKPSLLLRPHGKDE----------RLVTVRLLPCPPLDFFRPCRLLPTKNNVRSAWYRGQSCPDY---EPPTPHYNTWILQDVALETHMHLLASVLGSAQGLKDGVALLKVWLRQRELDK------GLGGFNGFIISMLVAFLVS------KRKIHTTMSGYQVLRSVLQFLATTDLTINGISFSLSSDPSLPTLAEFHQLFA----VVFVDPSGRLNLCADVTASTYNQVQYEAELSMALLDSKADDGFQLLLMTPKPMIQAFDHVVHLHPLSRLQASCHQLKLWPELQDNGGDYVSAALG-----PLTNILVQGLGCRLHLLAHSRP-PVPEWSINQ------DPPKHKDAGTLTLGFLFRPEGLTSVIDLGPEA---DKPEAADFRQFWGTRSELRRFQDGAIREAVVWEAE--SLFEKRLIPHQVVTHLLALHADIPDTCIQYVGGFLDALIQN-------------PKEISSTGEEALALAVRCYDDLSRLLWGLEGLPLTVSAVQGAHPVLRYTEVFPPAPVRPAYSFYNRLQELASLLPRPDKPCPAYVEPMTVVCHLEGSGQWPQDAEAVQRVRAAFQLRLAEVLTQEHRLQCCATATHTDVLK------------DGFVFRIRVAYQR-EPQILKEVRSPEGMVSLRDTPASLRLERDTKLLPLLTSALHGLQQQYPAYSGVARLAKRWVRAQLLGEGFT-DESLDLLAASLFLHPEPFTPPSVPQVGFLRFLYLVSTFDWKNNPLIVNLN-----------------------------GELTAEEQVGIRSSFLAARTQLP---VMVIITPQDRRSS--VWTQD-GPSAQILQQLVSLAAEALPILEKQLMDPRGPGD-IRTVFRPPFDMYDVLIHLTPRHIP-RHRQAVDPPVASFCRGLLA-EPGPSS-LMPVLGYDPPQLYLAQLREAFEDLALFFYDQHGGEVIG------VLWKP-SSFQPQPFKASSIKGRMVVSQGGELVMLPNIEAILEDFAVLGEGLVQAVEARSERWTV------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6R4-1", "uniprot_id": "NOL6_HUMAN", "id": "Q9H6R4-1", "name": "Nucleolar protein 6", "aln": "--------------MGPAPAGEQLR--GATGEPEVMEPALEGTGKEGKKASSRKRTLAEPPAKGLLQPVKLSRAE---LYKEPTNEELNRLRETEILFHSSLLRLQVEELLKEVRLSEKKKDRIDAFLREVNQRVVRVPSVPETELTDQAWLPAGVRVPL-----HQVPYAVKGCFRFLPPAQVTVVGSYLLGTCIRP--DINVDVALTMPREILQDKDGLNQRYFRKRALYLAHLAHHLAQDP------LFGSVCFSYTNGCHLKPSLLLRPRGKDE----------RLVTVRLHPCPPPDFFRPCRLLPTKNNVRSAWYRGQSPAGDGSPEPPTPRYNTWVLQDTVLESHLQLLSTILSSAQGLKDGVALLKVWLRQRELDK------GQGGFTGFLVSMLVVFLVS------TRKIHTTMSGYQVLRSVLQFLATTDLTVNGISLCLSSDPSLPALADFHQAFS----VVFLDSSGHLNLCADVTASTYHQVQHEARLSMMLLDSRADDGFHLLLMTPKPMIRAFDHVLHLRPLSRLQAACHRLKLWPELQDNGGDYVSAALG-----PLTTLLEQGLGARLNLLAHSRP-PVPEWDISQ------DPPKHKDSGTLTLGLLLRPEGLTSVLELGPEA---DQPEAAKFRQFWGSRSELRRFQDGAIREAVVWEAA--SMSQKRLIPHQVVTHLLALHADIPETCVHYVGGPLDALIQG-------------LKETSSTGEEALVAAVRCYDDLSRLLWGLEGLPLTVSAVQGAHPVLRYTEVFPPTPVRPAFSFYETLRERSSLLPRLDKPCPAYVEPMTVVCHLEGSGQWPQDAEAVQRVRAAFQLRLAELLTQQHGLQCRATATHTDVLK------------DGFVFRIRVAYQR-EPQILKEVQSPEGMISLRDTAASLRLERDTRQLPLLTSALHGLQQQHPAFSGVARLAKRWVRAQLLGEGFA-DESLDLVAAALFLHPEPFTPPSSPQVGFLRFLFLVSTFDWKNNPLFVNLN-----------------------------NELTVEEQVEIRSGFLAARAQLP---VMVIVTPQDRKNS--VWTQD-GPSAQILQQLVVLAAEALPMLEKQLMDPRGPGD-IRTVFRPPLDIYDVLIRLSPRHIP-RHRQAVDSPAASFCRGLLS-QPGPSS-LMPVLGYDPPQLYLTQLREAFGDLALFFYDQHGGEVIG------VLWKP-TSFQPQPFKASSTKGRMVMSRGGELVMVPNVEAILEDFAVLGEGLVQTVEARSERWTV------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4S6-1", "uniprot_id": "F1Q4S6_DANRE", "id": "F1Q4S6-1", "name": "Nucleolar protein 6", "aln": "----------MKKKRKDLTLTEDTIPETEVPESSQKEEAMQKKTGKLRSKDPKRKAKDTVSDDGVLRPVKLSKKE---LYKAPTVEELNQLKEAENLFHCSLLKMQMEELLKEVALSEHRKKLVDSFVQQVTEFLDCVPESEVMELNDVSWLSR-VEVPF-----FLVPAAATGKFHMEAPASVSLVGSYPLGTCIKP--RVCVDLAVIIPSSVLHPMDAINQRYPRKRALYLAGLAQHLSFLK------AVGSMSYSCLHGNRLRPVLLVKPSGKDG----------DKVTLRIHAIPPPDFLKPSRFHPRKNNVKTEWFTGVAKEEQGAAGPATPHYNSTVLGDHLPLSHLQFLSAVSAQCPAFREGVALLKVWLRHRELDQ------GAGCFCGFHASMLMAYLLS------THKVGKTMNAYQLFRNALHFLASTDLTENGITLAKNPDSKAPALPEFHAAFS----VVFVDPSGHLNLLAEMTTFTYKQIQHEASLSLKFWDDPTVDGFQTLLMTPKSMIRTYDNVFQLGELVKLQASCKKLSLLNELMDHSGNYVQTALP-----FILSLLKRGLGERIHLLVHSLP-PDPEWSVKS------PPPKHKDQSPLNIGLLLNLEHALSVLERGPPA---DNPKAAEFRQLWGSRSELRRFQDGAITEAVLWSGS--SACDKRLVLLEIITHLLHLHADIPHSCVRFVGGQLDDVIKV-------------NKELCTTGEEESLKVVQSYDDLSRKLWQLEGLPLSITSVQGAHQALRYTQVFPPVPVRLDYSFFDRKKNHLGLVPREDKPCPTYITPIKVIVHMEGSGKWPSEQLAIRHIKAAFHICLGELLTKHHNYKCHAKPNYVDVWK------------DGLAFRVEVAYHR-EPHILRESLTPEGMLIYRDNAEAQALELETQHKPFLTSTLHGLQQQHGCFGAVCRLAKRWLASQFLLEDVR-EEAADLIVASLFLHPAPFTPPSSPQVGFLRFLHLLSSFDWKNNPLIVNLN-----------------------------GKLTVADTTDIKNEFVSSRESLP---TMFIASPNDKKVS--IWTKK-VPSVQMLQRAVMLAAESLRVLENQLIDSSQKQD-VRVVFRPPLDAYDVLIHLIPQQVP-LLAKAVDAPALSFQQGTFKGEPATSGGALPVIDYNPVQLYLSELRDAFGDLALFFHDPFGGTVIA------VLWKP-NAFEPRPFKTSLMNARRVEMNGDVATVVPNVEAILQDFRIIGEGLVKKLELRTEKWVV------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IH00-1", "uniprot_id": "NOL6_DROME", "id": "Q8IH00-1", "name": "Nucleolar protein 6", "aln": "----------MRFVQGNIMPGKLVGSPKGAARTGTQAIAHAGDHSDLDEPKP-KIAKSDPPSTAIPKKNNFKQREGTKNVKPPTLEEMKELRDTQNLFHSNLFKLQVKEMLEELQLKQKYTDFIENWLESFTAFTRQLKDG----LMERTHLEVPMKLSE-----KPTGFVFS-----KPTREPYLIGAAATGTLLGP--KIVVDVALEMPKESLHKEDYLNLRYDQKRALYLTYVTERMMESPDY----AEDQFNFNYYANNPLKPVLELIPVTKQVN---------KHLQVRLFITAPLSSFKPGRFVPWNNNIRPSFYG--DEWDEKDPLPSTQHYNANVLFDLTLSENQAQLDKAFKSRRNFQDGLLLLKVWLRQRQLDI------GYSGFGAHILAAFIVYLNT------QRILHQSSSSYQVARTVWNQLANTDWTKG-ISLSVAP-IQTEELNKFAEHYD----VCFIDFTGQHNLCANIPLYLYQRVREEAKLAVELLNDMKLNSFPLIFMQKCPLYSRVDNILKISNYSCINQMLTLHSHPRIKYDFANYGYPQLLH-----LLTELLKKGLAERVHSILPLET-ATAAWPVEK------KAPVIG--KYIQLGLILQPEHAYQVLNKGPAAND-DHEGAEEFRRFWGEKSNLRRFQDGSITEAVVWGTAQDSPAKKRLIVRQIVLHLLEHHLQLDSKEVQYIGGELDQVYQLSPWFKVNKLKTKLPLGQDTDAEALSPHVIRCYDELARQLHGLNDLPLEIVSISGVSPIFRYCEPQPVLPQ----ALLVENRILASSIQR-------------VVIQLGQSGKWPTELGALRALKTAFLIEIGEKLEAQCRLHWVMSADGLLVLK------------QGYCFLIELAHNK-ELALLKQEVTERGITTYIDNAASRSLERQHYILPKVSGALHSLHQTYSAFGSTVLLAKRWLATQLLDDGLWPDMATELLVAHLFQQRYAPQSIAAPQTGFIRFLQLLSHSDFNGELFLLNFN-----------------------------NSWQEQQIADLEHNYRSNRQSYP---PLAVATSYDMQHAGRLWTSDQSPSQRVLGHVTRLARHALEIIETSLMSKDLRFVRPAQLFRASNEGYDLVIQFKPDLVPNSLSYDLGSPFVSFSQPNFS---------LPRAGSDYIARIVGLLRSAYSDFAAFFYNPHGGKELG------IVWRPPTEFAAKPFKVTELQACSPCGNKKVQVLK---ETLLEDFKLLLKDFYLRIATPEELKREQREHQKPMRYFDANKAEEESKPKPKKHRQRKGTGKKALPKRKRLIKSSTLKVLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53254-1", "uniprot_id": "UTP22_YEAST", "id": "P53254-1", "name": "U3 small nucleolar RNA-associated protein 22", "aln": "MATSVKRKASETSDQNIVKVQKKHSTQDSTTDNGSKENDHSSQAINERTVPEQENDESDTSPESNEVATNTAATRHNGKVTATESYDIHIARETAELFKSNIFKLQIDELLEQVKLKQKHVLKVEKFLHKLYDILQEIPDWEEKSLAEVDSFFKNKIVSVPFVDPKPIPQNTNYKFNYKKPD-ISLIGSFALKAGIYQPNGSSIDTLLTMPKELFEKKDFLNFRCLHKRSVYLAYLTHHLLILLKKDKLDSFLQLEYSYFDNDPLLPILRISCSKPTGDSLSDYNFYKTRFSINLLIGFPYKVFEPKKLLPNRNCIR------IAQESKEQSLPATPLYNFSVLSSSTHENYLKYLYKTKKQTESFVEATVLGRLWLQQRGFSSNMSHSGSLGGFGTFEFTILMAALLNGGGINSNKILLHGFSSYQLFKGVIKYLATMDLCHDGHLQFHSNPENSSSSPASKYIDEGFQTPTLFDKSTKVNILTKMTVSSYQILKEYAGETLRMLNNVVQDQFSNIFLTNISRFDNLKYDLCYDVQLPLGKYNNLETSLAATFGSMERVKFITLENFLAHKITNVARYALGDRIKYIQIEMVGQKSDFPITKRKVYSNTGGNHFNFDFVRVKLIVNPSECDKLVTKGPAHSETMSTEAAVFKNFWGIKSSLRRFKDGSITHCCVWSTS-SSEPIISSIVNFALQKHVSKKAQISNETIKKFHNFLPLPNLPS------------SAKTSVLNLSSFFNLKKSFDDLYKIIFQMK-LPLSVKSILPVGSAFRYTSLCQPVPFAYSDPDFFQD----------------------VILEFETSPKWPDEITSLEKAKTAFLLKIQEELSANSSTYRSFFSRDESIPYNLEIVTLNILTPEGYGFKFRVLTERDEILYLRAIANARNELKPELEATFLKFTAKYLASVRHTRTLENISHSYQFYSPVVRLFKRWLDTHLLLGHIT-DELAELIAIKPFVDPAPYFIPGSLENGFLKVLKFISQWNWKDDPLILDLVKPEDDIRDTFETSIGAGSELDSKTMKKLSERLTLAQYKGIQMNFTNLRNSDPNGTHLQFFVASKNDPSGILYSSG--IPLPIATRLTALAKVAVNLLQTHGLN----QQTINLLFTPGLKDYDFVVDLRTPIGLKSSCGILSATEFKNITNDQAPSNFPENLNDLSEKMDPTYQLVKYLNLKYKNSLILSSRKYIGVNGGEKGDKNVITGLIKPLFKGAHKFRVNLDCNVKPVDDENVILN-KEAIFHEIAAFGNDMVINFETD------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . : . . . ::: ::: **:..::::*:.*:*::: *.:: :: ::... : * : : :. . . ::*: : : :* : :* . :. * :* * :**::**: :: :: .. :. . * * * : . :.: * . :.* :: * .* :: *.* ** :* . * . : :. * ::**::* :. . . * . : ::. * . : : ..**: : . : **. * . . :.* : : *: :.:. *: :: * :: : :. : * ::: . . . : . . * : : .*. *:: : . : : . : : ::.. . .:: ** * *:.:** :*.****:**:* .. :* * : : : : : :: :: . . * :.:*:* : : :: *** : :: . :** . * . *: .: * :** : ::. ::** : : * * . . : * * ..: .: * *: . .. . : . : :*..: : : :. . * ***: :::* . : :*:. * . . . : **::.* ::* :::.: ::::: : :. : * . * : . . . : :::. . : : . ** :: :::. :. :* . . **.:: : . :... . : : *. : : : . * . :: . : ..* . *:::.:: : :.: . ", "identical_positions": 109, "similar_positions": 330, "identity": "8.09%" }, { "cls_id": "homologset.agr.MGI:2140175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C142-1", "uniprot_id": "ARH_MOUSE", "id": "Q8C142-1", "name": "Low density lipoprotein receptor adapter protein 1", "aln": "MDALKSAGRALIRSPSLAKQSWAGG-RHRKLPENWTDTRETLLEGMVFSLKYLGMTLVERPKGEELSAAAVKRIVATAKASGKKLQKVTLKVSPRGIILTDSLTSQLIENVSIYRISYCTADKMHDKVFAYIAQSQQNESLECHAFLCTKRKVAQAVTLTVAQAFKVAFEFWQVSKEEKEKREKANQEGGDVPGTRRDSTPSLKTLVATGNLLDLEEVAKAPLSTVSANTNNVDETPRPQVLGNNSVVWELDDGLDEAFSRLAQSRTNPQVLDTGLSAQDIHYAQCLSPTDWDKPDSSGIDQDDDVFTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAR1-1", "uniprot_id": "ARH_RAT", "id": "D3ZAR1-1", "name": "Low density lipoprotein receptor adapter protein 1", "aln": "MDALKSAGRALIRSPSLAKQSWAGG-RHRKLPENWTDTRETLLEGMVFSLKYLGMTLVERPKGEELSAAAVKRIVATAKASGKKLQKVTLKVSPRGIILTDSLTSQLIENVSIYRISYCTA-QMHDKVFAYIAQSQQNESLECHAFLCTKRKVAQAVTLTVAQAFKVAFEFWQVSKEEKEKREKANQEGGDVPGTRRDSTPSLKTSVATGNLLDLEELAKAPLSTVSANTKNMDDALRPQVLGNNSVVWELDDGLDEAFSRLAQSRTNPQVLDTGLTAQDIHYAQCLSPTDWDKPDSSGFDQDD-VFSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SW96-1", "uniprot_id": "ARH_HUMAN", "id": "Q5SW96-1", "name": "Low density lipoprotein receptor adapter protein 1", "aln": "MDALKSAGRALIRSPSLAKQSWGGGGRHRKLPENWTDTRETLLEGMLFSLKYLGMTLVEQPKGEELSAAAIKRIVATAKASGKKLQKVTLKVSPRGIILTDNLTNQLIENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLECHAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSKEEKEKRDKASQEGGDVLGARQDCTPSLKSLVATGNLLDLEETAKAPLSTVSANTTNMDEVPRPQALSGSSVVWELDDGLDEAFSRLAQSRTNPQVLDTGLTAQDMHYAQCLSPVDWDKPDSSGTEQDD-LFSF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************.** ********************:************:**********:******************************.**.**************** :*************:*:*************:*****************************:**.****** *:*:*.*****: *********** ************.*:*:. ***.*...*******************************:***:********.********* :*** :*:*", "identical_positions": 271, "similar_positions": 30, "identity": "87.7%" }, { "cls_id": "homologset.agr.MGI:2140179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8G6-1", "uniprot_id": "D4A8G6_RAT", "id": "D4A8G6-1", "name": "DDB1- and CUL4-associated factor 10", "aln": "MFPFGPHSPGGDG--AAGAEEPPPLGGPAAASRPPSPAPRPASPQRGADAASPPPATGSPRLRGSPAVSPAERAGELAAPEALELSAA---ASQAELSPSSSPRRRSRPDCKAGSWSRQGLSAGLGGPGARLFGWLRERSLGRGLFVDPARDNFRTMTNLYGSIHP-----ADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRCTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHDLDLT---------------------------------------------------------------------------------------------------------------KSLEVGSYPILRARRTTSSSDLTTSSSSSGSRVSGSPCHHNDSNSTEKHVSRASQREGVSPRNSLEVLTPEVPGER------------------DRGNCITS--LQLHPKGWATLLR---------------------CSSNTDDQEWTCVYEFQEGAPVR-PVSPRCSLR------------------------LTHYIEEANVGRGYIKELCFSPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASP-----LRVIRSLYSHNDVVLTTKFSPTHCQIASGCLSGRVSLYQPKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AKB9-1", "uniprot_id": "DCA10_MOUSE", "id": "A2AKB9-1", "name": "DDB1- and CUL4-associated factor 10", "aln": "MFPFGPHSPGGDE--TAGAEEPPPLGGPAAASRPPSPAPRPASPQRGADAASPPPVAGSPRLPGGPAVSPAERAGEFAAPGALELSAATASASQAKLSPSSSPRRRSRPDWRAGGRSRQGLGAGLGGPGARLFGWLRERSLGRGLFVDPARDNFRTMTNLYGSIHP-----ADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRCTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHELDLT---------------------------------------------------------------------------------------------------------------KSLEVGSYPILRARRTTSSSDLTTTSSSSGSRVSGSPCHHNDSNSTEKHMSRASQREGVSPRNSLEVLTPEVPGER------------------DRGNCITS--LQLHPKGWATLLR---------------------CSSNTDDQEWTCVYEFQEGAPVR-PVSPRCSLR------------------------LTHYIEEANVGRGYIKELCFSPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASP-----LRVIRSLYSHNDVVLTTKFSPTHCQIASGCLSGRVSLYQPKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QP82-1", "uniprot_id": "DCA10_HUMAN", "id": "Q5QP82-1", "name": "DDB1- and CUL4-associated factor 10", "aln": "MFPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPS----PLHP--GADATHPPPPARSPRRPGAPSLSPAPRSGELGLPGAPESSTA---SAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPGARLFGWLKERSLGRGLFVDPARDNFRTMTSLYGSIHP-----ADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHDLDLT---------------------------------------------------------------------------------------------------------------KSLEVGSYPILRARRTTSSSDLTTSSSSSGPRVSGSPCHHSDSNSSEKHMSRASQREGVSPRNSLEVVTPEVLGES------------------DHGNCITS--LQLHPKGWATLLR---------------------CSSNSDDEECTCVYEFQEGAPVR-PVSPRCSLR------------------------LTHYIEEANVGRGYIKELCFSPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASP-----LRVIRSLYSHNDVVLTTKFSPTHCQIASGCLSGRVSLYQPKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWH1-1", "uniprot_id": "DCA10_DANRE", "id": "Q6NWH1-1", "name": "DDB1- and CUL4-associated factor 10", "aln": "-----------------------------MSSGHPSDNEEPRADLLREEEEEEEEEEDSDEDRGSTRPASPQATRECAGTQG---------SSRPEVTADGGTGSASGSGCRG------------SGACDSLFSWICRRKIRRGPYVDPARDHFRTMTRLYSSMSPA----ADSVNLSTQTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPVSSRHIKTLVEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNSKVCSLHGHASWVKNIEYDTHTRLLVTSGFDGNVITWDTNRFTEDGCPHKKFFHTRYLMRMRLTPDCSKMLISTSSGYLLILHDLDLT---------------------------------------------------------------------------------------------------------------QSLEVGSYRILRARRPP----LSTEGSSAGSR-SGGPRHTIDNKN-------HPHREGLSPRNSLEVLTPEIPGER------------------DRGNCITS--LQLHPKGWATLLR---------------------CSSNMDDQEWTCVYEFQEGAPPRPPVSPRCSLR------------------------LTHYIEEANVGRGYIKELCFSPDGRLICSPYGYGVRLLAFDENCAELVDCMPVRTAQ-----LREVRSIYSHSDVVLTSKFSPTHCQFASGCLSGRVALYQPHF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAT2-1", "uniprot_id": "DCA10_DROME", "id": "Q9VAT2-1", "name": "DDB1- and CUL4-associated factor 10 homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MERYLSRRESG---FHIHRSDDNSLMRRIYSSMNMFNSYHANCWPTDAGRTGAIFNLEFNADGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFFDERLFATGSDDFTVALWDLRNMKQKLRVLHGHSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISPTGDKLVLCTSGGYIMIIHHLDLTTLHKDLCGFRPGIYRLMQLGEQYIPQAAKYDHVFSKRQKKNRVELVTDFPENNDAEMIMALQIHPHCCCMLTRNVSCDEQSEWTCIHDINEEPVRSEDEQDEVEPQPKRKRVSTTLASRSSLNESQDQDTVGLTPRQARRPLRVSSVQVFQLDNSGAGRGASDNPSVLTRSDSFIPDIWAAEVTVQERAIRQNRARVSNNHVSGYNFVYAISSGVLPLRQLGANSLMGSSTSPRPLTTPPPTESNQSSSSSSSSSSSSSSSSSSNNSDTTVRLEIGNRLRLRSFNSPVTTPTFKENGHSILVNAKKLLYYAAETNTKPGFIKEPGFSADGRVVCSPYGNGVRLFGYSEDCCDYPKCQAFEEVKSKPRKLVELAKITEHQDVVLCAKFSPREPLLVTGCNGGEVTWYRPNL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: .*. : *. * :*.*: *:. .: **:****:..**.*:..* *:. **:**.::.:.* .: :** *.** *:*:*:***** *** *:******::: *: ****:.*******.:: :***:*****.:: ** * **:* ::.**: *** *::* .*:::.**.**::*:*.**** * :.* *. : *:. : * *. . *... . * :: :.*: : : .*:* * *: * :*: .**. .... :. . :..:. * :. * ** * :* *:*. *:*** **.***::.**:* *:**:.:.::*.: .* . . * : .: .*.**** :**** . :.:** .*.*: *:*::", "identical_positions": 147, "similar_positions": 148, "identity": "19.47%" }, { "cls_id": "homologset.agr.MGI:2140197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVR5-1", "uniprot_id": "ACNT2_RAT", "id": "Q5FVR5-1", "name": "Acyl-coenzyme A amino acid N-acyltransferase 2", "aln": "-MLQLIATPSNALADEPVSIRAIGLPPSQIVTITATVKDEKENLFQSKAFYKANEAGEVDLEQASALGGDYVGVHPMGLFCCLKPKRAFQRLIKKDVMNSPLCICLDLYDSVCWLETVRIPPKASQIVHRWFAGPGVKREQIREGRVRGALFLPPGKGPFPGIIDLFGSIGGLVEFRASLLASRGFAVLALAYFAYEDLPKVLLEEDLDYFEEAANFLLAHPKIQQPGIGVISVSKGAEIGLAMACYLKQVVATVCINGPSAIFDFPLKYRDLVVTPMRLAFEKIQFHGSGAACFRHCWDPQNMLNPPKILPVEKAQGKILFIVGENDQCLASKLHAQRAMDRLRSHGRSSGRMLAYPGAGHLIEPPYSPFCFACWDSVLGKPMLWGGDPIAHAAAQVHSWREIQKFFRQHLLQSGGKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AKK5-1", "uniprot_id": "ACNT1_MOUSE", "id": "A2AKK5-1", "name": "Acyl-coenzyme A amino acid N-acyltransferase 1", "aln": "MMIKLIATPSNALVDEPVSIRATGLPPSQIVTIKATVKDENDNVFQSQAFYKTNEAGEVDLEKTPALGGDYVGVHPMGLFFSLKPKKAFHRLMKKDVMNSPFCICLDLYDSVNWLETVRIPSKASQRVQRWFVGPGVKREQIQEGRVRGALFLPPGKGPFPGIIDLFGVIGGLVEFRASLLASHGFAVLALAYFAYKDLPEKLQEVDLEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGLAMACYLKQVIATVCINGATTTTAVPLRYQDLVVTPIQQALERMEVHVSGAVCFRHTT---QYLQNKNILPVEKAQGKILFIVGENDELLDSKLHAQRAMDRLRRHGRSSGRMLAYPGAGHLIEPPYSPLCFASWQPVLGRPMCFGGDLMAHAAAQEHSWREIQKFFRKHLLQSGSKL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::*********.******** **********.******::*:***:****:*********::.*************** .****:**:**:********:********** ********.**** *:***.*********:************************* **************:************:***: * * **:**********:*************.*****************:*******.:: .**:*:******:: *:*:::.* ***.**** : *: :*******************: * ************* ************************:***.*:.***:** :*** :****** ***********:******.**", "identical_positions": 336, "similar_positions": 55, "identity": "80.19%" }, { "cls_id": "homologset.agr.MGI:2140201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG11-1", "uniprot_id": "D3ZG11_RAT", "id": "D3ZG11-1", "name": "", "aln": "MSKELAAMEPGASRDGLRAETT-HQALGSGVSLHTYDIVVVVIYFVFVLAVGIWSSIRASRGTIGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATFLLLALGWIFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTVILLVVTAVYTIAGGLTAVIYTDALQTVIMVGGALVLMFLGFREVGWYPGLQQLYRQSIPNVTVPNTTCHLPRSDAFHMLRDPVNGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALYPDEVACVDPDICQRVCGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFAIDVWQRVRRQASEQELMVVGRLFVVFLVLISILWIPIIQSSNSGQLFDYIQSITSYLAPPITALFLLAIFCKRVTEPGAFWGLMFGLVVGILRMILEFSYSAPACGEKDRRPAVLKDFHYLYFALLLCGLTAIIIVIISFFTEPIPDEKLARLTWWTRSCPISELQKKVSVSVNNTESDNSPALAGRPVMEGTAGDEEEANTTSEPEQPEVLHRSWGKWLWNWFCGLSGTPQQALSPAEKAELEQKLTSIEEEPLWRCVCNINAIILLAINIFLWGYFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDT1-1", "uniprot_id": "SC5A9_MOUSE", "id": "Q8VDT1-1", "name": "Sodium/glucose cotransporter 4", "aln": "MNTELVAMEPGVSRNGVRTETT-TNPS---LGLHTYDIVVVVIYFVFVLAVGIWSSIRASRGTVGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATFLLLALGWIFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTVILLVVTAVYTIAGGLTAVIYTDALQTVIMVGGALVLMFLGFQEVGWYPGLQQLYRQAIPNTTVPNTTCHLPRPDAFHMLRDPVNGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLAAKNLSHAKGGSVLGGYLKILPMFFIVMPGMISRALYPDEVACVDPDICQRVCGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFAIDVWQRFRRQASEQELMVVGRLFVVFLVVISILWIPIIQSSNSGQLFDYIQSITSYLAPPITALFLLAIFCKRVNEPGAFWGLMFGLVVGILRMILEFSYSAPACGEMDRRPAVLKDFHYLYFALLLCGLTAIIIVVISFFTEPIPDDKLARLTWWTRNCAVSDLQKKTSVSVNNTEDDNSPGLAGRPVVEGPAGDEEEANTTQGPEQPGALHRSWGKWLWNWFCGLSGAPQQALSPAEKAVLEQKLTSIEEEPLWRRVCNINAIILLAINIFLWGYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M3M2-1", "uniprot_id": "SC5A9_HUMAN", "id": "Q2M3M2-1", "name": "Sodium/glucose cotransporter 4", "aln": "MSKELAAMGPGASGDGVRTETAPHIALDSRVGLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIPEEQLTRLTWWTRNCPLSELEKEAHEST--------PEISERPAGECPAGGGAAENSSLGQEQPEAPSRSWGKLLWSWFCGLSGTPEQALSPAEKAALEQKLTSIEEEPLWRHVCNINAVLLLAINIFLWGYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WHP3-1", "uniprot_id": "SC5A9_DANRE", "id": "A8WHP3-1", "name": "Sodium/glucose cotransporter 4", "aln": "MPASPEPVTATPEPEEVPAKFT----------LEAADIAVVVVYFVFVLAVGIWSSIRANRGTVGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNAAWVLIALGWIFVPVYISAGVVTMPEYLRKRFGGQRIRIYMSVLSLILYILTKISTDIFSGALFIQVSLGWDLYLSTVILLAVTALYTIAGGLTAVIYTDALQTVIMVIGAFVLMFIAFDKVGWYEGLLVQYEKAAPALTVPNTTCHLPRSDAFHIFRDPVTGDIPWPGLIFGLTVLATWVWCTDQVIVQRSLSAKNLSHAKAGSVLGGYLKVFPMFFVVMPGMISRALYPDEVACVDPDECQKICGAKVGCSNIAYPKLVVELMPVGMRGLMIAVMMAALMSSLTSIFNSSSTLFTMDIWQRIRPRASEKELMVVGRVFILLLVALSIVWIPVIQTANSGQLFDYIQAITSFLSPPITTVFIMAIFWGRVNEQGAFWGLMVGLVVGMVRMIMEFVYGTPSCGETDLRPSLLKDVHYLYFALILLALTVLIITAVSLCTAPIPEKHLVRLTWWTRHSKEERVELEDPWAK-------------------PAGSDLSTTESEGSDEDAP---AWWKRAGMWLCGLSQTTKQDLTEEERQALEKKLTSIEEDHMWKTVCNVNALILLTANVFLWGYFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .: . . : : :: : *.: ** ***:*****:**********.***:**********:***************************************:::*:****:******:*******:**:********::***********:***************::***:***** ***.***:******* ************** **:****:.* .**** ** *.:: * ***********.****::****.****************** ************:**.*****.*********::****:**********:****.***** **::***:************: *****:*******:*******************::*:***.* :::*:*******:*:::** :**:***:**::**********::**:*:****::*::*** **.* ******:.** **::***:** * :*:*** * **::***.******::* .**.::*. :*: * ***:.:*.******* . . :: : : .**. . : :: :* * *:**** :.:* *: *: **:*******: :*: ***:**::**: *:*******", "identical_positions": 447, "similar_positions": 135, "identity": "64.88%" }, { "cls_id": "homologset.agr.MGI:2140219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZT5-1", "uniprot_id": "LRC19_MOUSE", "id": "Q8BZT5-1", "name": "Leucine-rich repeat-containing protein 19", "aln": "MKVT--RFMFWLFSMLLPSVKSQASETEVPCNFSRRNYTLIPEGISTNVTILDLSYNRITLNAADSRVLQMYSLLTELYLMENNIIALYNSSFRNLLNLEILNICGNSISVIQQGSFVGLNELKQLFLCQNKILQLNPDTFVPLNNLKVLNLQGNLIRLFDAPQLPHLEILTLDGNPWNCTCGLLELHNWLNTSNVTLENENMTMCSYPDELKHDSIKSAPFTTECHSTFISTITEDFQSTRN----SSFNSSSHNLTWTSEHEPLGKSWAFLVGVVATVLLTSLLIFIAIKCPVWYNILLSYNHHRLEEHEAETYENGLTRNPSSLSQITDTNSEDTTVIFEQLHAFVVDDDGFIEDRYIDINEVHEEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6K7-1", "uniprot_id": "D4A6K7_RAT", "id": "D4A6K7-1", "name": "Leucine-rich repeat-containing protein 19", "aln": "MKVT--RFMFWLFSMLL-SDKSQASETEVKCNFTRKNYALIPEGISSNVTILDLSYNQITLNASDTRTLQMYSLLTELYLMENNITALYNNTFSNLLNLEILNICGNSISVIQQGSFVGLNELKQLFLCQNKILQLTPDTLVPLNNLKVLDLRGNLISLFHAPRLSHLELLTLDGNPWNCTCGLLDLQNWLNTSNVTLENESITTCNYPDDLKHYSIKSAPFTTECHSKFISTIAEDLYID--------FNRSLKNLTWNSEHEPLGKSWAFLVGVVATVLLTSLLIFIAIKCPIWYNILLSYNHHRLEEHEAETYDQGLTRNPSSLSQITDTNSEDNTVIFEQLHSFVVDDDGFIEDRYIDINEVHEEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H756-1", "uniprot_id": "LRC19_HUMAN", "id": "Q9H756-1", "name": "Leucine-rich repeat-containing protein 19", "aln": "MKVTGITILFWPLSMILLSDKIQSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTEDLYIHFQPISNSIFNSSSNNLTRNSEHEPLGKSWAFLVGVVVTVLTTSLLIFIAIKCPIWYNILLSYNHHRLEEHEAETYEDGFTGNPSSLSQIPETNSEETTVIFEQLHSFVVDDDGFIEDKYIDIHELCEEN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ::** :**:* * * *:*: ** ***:.:**:*** .*..:*********:****.:*:*.** * *******:**:: *:*. * ** .******* *** *****:*:***:****:****** **..*.:***..**:*:*:**** :..* * ***::** ** ***:*.*::*:*************.:* *.**:.*: .**:.*..:****.* *:::**: ** * :*** .*****************.*** ************:*********************::*:* ********.:****:.********:***********:****:*: **:", "identical_positions": 242, "similar_positions": 81, "identity": "65.41%" }, { "cls_id": "homologset.agr.MGI:2140220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PDI5-2", "uniprot_id": "ECM29_MOUSE", "id": "Q6PDI5-2", "name": "Proteasome adapter and scaffold protein ECM29", "aln": "-------------------------------------MYHIDCR--------DQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDP-----AAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPAESSKSASPFN---LAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSSSQGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIIN-KMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICLTCPEIKIKPLGPMLLNGLTKLINEYKEDPK-LLSMAYSAVGKLSSRMPHLFTK--------------------DIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEG--------------------AQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGD----------------PREEVHGEAQRVLRCLPGRNKKESASKQ-----------MPSFPEMVYYIQEKASHRMKT-PVKYMTGTT--VLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRALMSSSQATASSSNKSGETNPVQIYTGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMSSSKEEMRELAALFYSVVVSTVSGIELKSMIEQLIKATKDNHSPEVQHGSLLALGFTVGRYLAKKRVRMAEQHDLETDADLLPEQEEIIRSATETIGSFLDS--TSPLLAIAACTALGEIGRNGPLP-------IPSEG--------------SGFTKLHLVESLLNRIPSSKETNKMKERAIQTLGYFPVGDGVFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTNSVAARDAWLVTEEEYIPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHREVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTGKR---------VKHEVSGETVVFQGGGLGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLP-----QLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVDKYLKEILQDLIKNLTSNMWRVRESSCLALNDLLR--------------------GRPLDDVID-KLPEMWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQR---TIAVLLPCLLD-KGMMSPVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEK---------DVMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYME-KDEPVYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNMWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASISKQTS-SLVPPYLGMILSALMQGLAGRTWAGKEELLKAIACVVTACSTELEKSVPNQPTTNEILQAVLKECCKENLKYKIVAISCAADVLKATKEDRFQEFSDIVIPLIKKNSLESMG-----VRTTKAEDENE--KERELQLESLLGAFESLGKAWPRN-PDTQRCYRQELCKLMCERLRLSTWKVQLGVLQSMNAFFQGLMLLEEEHADP---------------------EALAEILLETCKSITYSLENKTYSSVRTEALSVVELLLKKLE---------------------------EAKQWESLTAECRGLLIESLATMETDNRPELQEKASVLKKTLESLE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A123-1", "uniprot_id": "A0A8I6A123_RAT", "id": "A0A8I6A123-1", "name": "Proteasome adapter and scaffold protein ECM29", "aln": "MRAIQSAIPNGLPACLSFLSLSFLDFLWILGQHIWNSLHWLQICGSSLESYMYQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDP-----AAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPAESSKSASPFN---LAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSS-QGSSSNSGGSSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIIN-KMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPK-LLSMAYSAVGKLSSRMPHLFTK--------------------DIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEG--------------------AQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGD----------------PREEVHGEAQRVLRCLPGRNKKESASKQ-----------MPSFPEMVYYIQEKASHRMKT-PVKYMTGTT--VLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRTLMSSSQATASSCNKSGETNPVQIYIGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMSSSKEEMRELAALFYSVVVSTVSGKELKSMVEQLIKATKDNHSPEVQHGSLLALGFTVGRYLAKKRVRMAEQHDLETDDDLLPEQEEVIRSATETIGSFLDS--TSPLLAIAACTALGEIGRNGPLP-------IPSEG--------------SGFTKLHLVESLLNRIPSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTSSVAARDAWLVTEEEYIPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHVEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYDLGSEQDQQELVSTLVDTLRTGKR---------VKHEVSGETVVFQGGGLGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLP-----QLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVDKYLKEILQDLIKNLTSNMWRVRESSCLALNDLLR--------------------GRPLDDVID-KLPEMWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQR---TIAVLLPCLLD-KGMMSPVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEK---------DAMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLTAWYME-KEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNMWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTS-SLVPPYLGMILSALVQGLAGRTWAGKEELLKAIACVVTASSTELEKSVPNQPTTNEILQAVLKECCKENLKYKIVAISCAADVLKATKEDRFQEFSDIVMPLIKKNSLESMG-----VRTTKAEDENE--KERELQLESLLGAFESLGKAWPRN-PDTQRCYRQEMCKLMCERLRLSTWKVQLGVLQSMNAFFQGLMLLEEEHADP---------------------EALAEILLETCQSITYSLENKTYSSVRTEALSVIELLLKKLE---------------------------EGKQWESLTAECRRLLIESLATMETDNRPELQEKASVLKKTLESLE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VYK3-1", "uniprot_id": "ECM29_HUMAN", "id": "Q5VYK3-1", "name": "Proteasome adapter and scaffold protein ECM29", "aln": "---------------------------------------MAAAAASASQDELNQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDP-----AAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPVESSKSASPFN---LAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSA-QGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIIN-KMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPK-LLSMAYSAVGKLSSRMPHLFTK--------------------DIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEG--------------------AQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGD----------------PREEVHGEAQRVLRCLPGRNRKESTSEQ-----------MPSFPEMVYYIQEKASHRMKT-PVKYMTGTT--VLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRTLMSSGQMAPSSSNKSGETNPVQIYIGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMNNSKEEMRELAALFYSVVVSTVSGNELKSMIEQLIKTTKDNHSPEIQHGSLLALGFTVGRYLAKKKMRMSEQQDLERNADTLPDQEELIQSATETIGSFLDS--TSPLLAIAACTALGEIGRNGPLP-------IPSEG--------------SGFTKLHLVESLLSRIPSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTSSVAARDAWQMTEEEYTPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTGKR---------VKHEVSGETVVFQGGALGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLP-----QLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLR--------------------GRPLDDIID-KLPEIWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQR---TIAALLPCLLD-KGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEK---------AAMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYME-KEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNLWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTS-SLVPPYLGMILTALLQGLAGRTWAGKEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADILKATKEDRFQEFSNIVIPLIKKNSLESSG-----VRTTKNEEENE--KEKELQLEYLLGAFESLGKAWPRN-AETQRCYRQELCKLMCERLKLSTWKVQLGVLQSMNAFFQGLMLLEEEHADP---------------------EALAEILLETCKSITYSLENKTYSSVRTEALSVIELLLKKLE---------------------------ESKQWECLTSECRVLLIESLATMEPDSRPELQEKAALLKKTLENLE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5L1-1", "uniprot_id": "B8A5L1_DANRE", "id": "B8A5L1-1", "name": "", "aln": "---------------------------------------------MAAQDELNQLERVFLRLGHAETDEQLQDIISKFLPPVLLKLSSVQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDP-----SAASFVTNFTIIYIKMGYPRLEVSKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLYHMKYPSEPSK-ASPFV---LTERPKTVHLLLEFMLDVLLMPYGFVLNEPPSRPAPSSPQGGSGAGATATQGLPQPPPGMSVYAVKRVIGEAQWSPEQLEQCKLGIVKFIEAEQVPEVETVIHLVVASSDTRHSVATAADLELKSKQSIIDWNNPLIIN-RMYKVYLGDIPLKTKG-ATVKQELKHEPVSTRVKMKILPHLLRSRLAAECFPANIQVVYDGLFGANTNNKLLSLTLQFVHHICMVCPDTN-KPLGLMLLNGLTKLINEYKEDPK-LLCMAYSAVGKLSSRMPQLFTK--------------------DIALVQQFFESMCKEEADVRLAIQEALSMMVAAYANLQG--------------------ALLNLMEALVAAYITKPEVQVRQVAMKFASTVFAPDHVASRFLLLLAAGD----------------PREEVAGEAQRALRSLPSTKTEKEGSRP-----------MPSFPEMVSYIQEKAAQRLKT-PAKYIVGTS--TLPFNPATFSEIVLYLRMCLAHSSGATPTSQSLMDMQDDAPLIGRYVQSLLSN-EASLSSATKGGDANPVHIYIDLLQQLLSAVGGIPVMYCLLEVVSVCPEKLTAKFVDKIDWIKGLMNTNKEDMRELAAQLYAVVVSTMSGNELRTAVQNLIKTTKDMHSPETQHGAILALGYMVGRYMNKKRNLMP-------SEATSREDEELIAMATKTIGSFLNS--ESALLTIAAVTALGEIGRNSVLL-------IPADG--------------NGFTKLSLVDNLLTRIPSGKETGKMKERAIQTLGFLPVGDGEFPHQKKVLQGLMDSVEAKQVELQFTVGEALTNAAVGSCSGAARDVWTCTEDQYCPPENVKNNDIVPWVLNSVLSKYIPSPNPHVRQAACIWLLSLVKKLSHHKEIQSHLKEIQTAFISVLSDPDELSQDVASKGLGLVYELGGEQDQQELVSTLVETLMTGKR---------AKHAVSEDTEVFQGEALGKAPDGQGLSTYKELCSLASDLNQPDLVYKFMNLANHHAMWNSRKGAAFGFNIIAAKAGEQLAPFLP-----QLVPRLYRYQFDPNLAIRQAMTSIWDALVTD-KTIVEKYFKEILQDVISNLTSNMWRVRESSCLALNDLIR--------------------GRQADEIID-RLSEIWETLFRVLDDIKESVRKAADLTLKTLSKVCVRMCEST-GATAQR---TVAVLLPTLLD-KGIVSNVTEVRTLSIQTLVKISKSAGSRLKPHAPRLIPALLEALSVLEPQVLNYLSLRATEQEKDIHNFFLRQSAMDAARLSAAKSSPMMETINMCLQHLDVSVLGELVPKLCDLLKSGIGLGTKGGCASVIVSLTVQCPQDLTPYSGKLMSALLNGINDRSSVVQKSFAFAVGHLVRTAKDSSVEKLLQKLNTWYLE-KEEALYKSSCCLVVHAISHYSPDVLKAHAGVALPLAFLGMHQEAEEEKGESAEANLWSEVWQEHVPGSFGGIRLYMTELIGITQRALQSQSWKMKAQGAAAMATIAKQQTGSLVAPHLGMVLTALLQGLAGRTWAGKEELLKAVGSVVSKCSVELQKPAAGQPTVSEVLDLVLKECKKESLVYKMAALRSAADILESTQVDRFHEVAEIVLPLIKKNQPASAS-----SPRHDDDDDDDDAKARELQTEVLLCAYETLGKAWPKT-IQTQNQFQNEVCNLMCERLKLSTWRVQLGVLRAMKVFYQGLLLLDKEHQNA---------------------AVLTELLSETCTALASPLENKSYSSVRTDALAVVELLLKRIEGIDDLHFHKTNLCDHRKALFVCVSNVPESDQWHCLCERSRQQLQRSLGTMETDSRPDLKDKAQTMRRKIQALP------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V677-1", "uniprot_id": "ECM29_DROME", "id": "Q9V677-1", "name": "Proteasome-associated protein ECM29 homolog", "aln": "-------------------------------------------METGPNAEIELLERVLLRLGNADSDEKLEAAVGKFLTPVILKMNSPHNVVRTKVVEVLTHIKRRLSSRGHVQIPVEALLDQYAAQ-----DSSTFLKNFAIIFITMGFPRLALEQQTALAS-KVVGCEDKLESYQDKLFALLLPVLSDMKIPDDPTQRSKLLD---LQDKPAICANFLALLQDVLLLPYGITQEQ-------------------------DVPPGLSPYSFTRIIAYN-WRAEELEKVKKGIVRFLCASVFSDLQIFVPLVVASADTRFSVATPAITELSKLCTMLDFSNPAVTA-PLYTLFAGNQ--------SKITDRQTRPCCARVRQKLLQYLIKCRGKSINVTKGLQVTFDGFFGTNTNQKCKVLALQFMELLLRDGPRELVSKVSKVILTGITKIIGRDSNEPNDVQNAAYSALAQHARSFPQDVSQ--------------------DLKLVLGYFNNLASCAPELHSSIREALVSMAPAFAWKTKEKSDAMEVDKNVDSSSVKLDGQQHLLLAMLLDNAESKVQIVQNVTSVFLTSCYPEYYAPARYLLLLIAGERNSLRENVTTYLYGTSKKDHINYSMLSSIDHSKNRISSESISDFNHLSLEQRRVMLPSFQVMMSHVHEMAEKRLKKNTACVVVGRT--KLPYSLEVYEELLDYLRLCLWYSAGVVAAPGDEKYTHELR---------------EYITLHYEDTEDNALHQYAQFVQRSVEAKRSESNLICLYDLLNAAPELFAAKQLHLLEPLGNTLKDVSETMRINVAQVYGILWAFGLSDEKFDEEVGECLNSLTQKTLEHKHGWLLVVGHTFNRKIAMLK---------QENKTKDFAAWPQFVNAVKIISKCLCE--SQWLLVSAAVKCISMIGKAVEIPNVPVEIQVPSKDGDDDDEEMTEYTSIDSSTKLVIFGVVFQLLRSSSARQKIREDSARCLGYLAIGDGEHFTKRNLDKFLTLTKIQKDAALNIAISEAIVNTLCG------YDVNKGQPDEKFVNKHCNDDDFDQFLNSLIR--LVTDPNPHSRQAISVWLLAVVKHCSQRPAVLAKKELLQFAFTELLSDDSEFVQDVASRGLGLVYSISDSGSQSDLANSLLDQLIGGKR---------KVNQVTADTELFAEGMLGKTPTGGNITTYKELCSLASDLNQPDMIYQFMQLANHNATWTSKLGAAFGLKTLSAESRQKMEPYLG-----KIIPRLYRYKYDPTPKIQNSMISIWDTIVTDSKEVTERYYWEILRELLDNLTCKEWRVRIACCLAVRDLLNRPNGLKLRSEEPVRRALPDNSMEVDEVPEPELKELWFQLFRVMDDIHEGTRVAAHGTASFLGKLCVIASSSDHGKSGTA---VASSILPFLLE-TGVGHKVPEIRRVSIKTISDMIDSSGSLIAPHLATLIPCLLRATGELENTKLSYVSTRLGADNEAQ-------EAVDTLRAEAAKSLHTMETIGKCVRYIDYSVLEKMTPEVLELMKGSVNLGTKIGCAHFVCLISIRLGKEMTPLVGKYIRACFVGIKNRNATVRKYNASAIGHLLGLAKEQSIKSLFTKLEELYAE-QPG---NRSIALTIQSINKRHHELLKDYMDSMLPLIFFAMHEEPNEE--TKANVELWKDLWHDVSPGDAG-IRLNLNVIIPKLESSLTDASWSRKAQAANAIQTIATRLSSSLDEPDRLRLIKLLLSGLQGRTFEGKERLLQALAALTKG-------LDRNHQICSSIIDAAMREARKREPVYRTMALASLGEILDQLEADRFEEVYNMSWNLLEKKELRKESDDEDEPNTSQELSADERNKRAQTLNRLKEVVWETLGKSWPRHSIETQHRYQLFFAENCTSILAESTRPVQVSLLAALTKYIERLHVFDESAQVPDLTQINQEKKIKTEETAPKTREAIVEKICTDVLAAVALAAGVPHSGLKKEALNIVLMLIKRLSG--------------------------SGNGNQQPLRLIKQSFESNLEKFQRDSAPEIRCRIKDIEDKLSKLNPQN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38737-1", "uniprot_id": "ECM29_YEAST", "id": "P38737-1", "name": "Proteasome component ECM29", "aln": "-----------------------------------------MSISSDEAKEKQLVEKAELRLAIADSPQKFETNLQTFLPPLLLKLASPHASVRTAVFSALKNLISRINTLPQVQLPVRALIVQAKEPNLAAQQDSTNVRLYSLLLASKGIDRLSLQDRQQLLPLVVSNISCLTGTVAARMFHILLKLILEWVAPQESSHEQEEFVQFLQLDNDGFSFLMRQFTRFFLLVPSKQVQVSQQP----------------LSRGYTCPGLSLTDVAFFTYDAGVTFNKEQLNKFKKAIFQFVCRGMAATQTIEQSPRMIELMEFLCVVSTDSTNLSDDAAQFMKRFPMPYENEEFITFLQTLYIG-------NTANGRPPVKAILQEKILSILNRSHFATTKAECISLICSIGLHSS--EYKLRSLTLSFIRHVAKLNYKNLNPASSSPSSTDFSTCIVSLIRNNLHAEGWPKLQLGPQTPAFNTAILQRQLQYETLGDILKRDFELVSDLSYIEFLFESLKNDLPQFRSSIQESLLSLVGHLSILPQQSKLKLKN-------LLRKNLSIDEQQREDNNDAVNSIMALKFVSIKFTNAAFPFHDPEARLFNIWGTVR---------------TNRFDIIEESFKGLQPFWFRVNNASINTS---------ATVKTSDLLGSHLSETEFPPFREFLQVLIDQLDSEAASITRKSLNNAVRFSKQCLIS--NAIYGKKTMVIQDEDWSVRIDKALELDDTVVSRVNEMVQGMNDDIFIRYLTLLSNEFTATNSKG------EQIAIFPYQDPIFGSVLLTLLNFVSNNVLRRLEILVPDLYHLVIMKFQSLSDNDLAVCATIIGIISTAIADSTHVKRITKIAQSQTMAETYVASYVVPRLYLKDQTNHIESDSILNLLNILTTHLSHPGTNKDMILKLVCQVTKFGLLLQVS---------------------------AQERKDFLKKVMDTIQDKLIN---DVTAIQTWSYLSLYSTDLENSSLFQEKLLETNVSKQNDFLFSVGESLSVVAGKWSSKYLIKQIDIPNFNVEIMQQKFPATNVTTILDEIFS-GCDSTKPSLRKASCIWLLSYIQYLGHLPEVSSKCNDIHLRFMRFLADRDEFIQDSAARGLSLVYEIGGSDLKESMVKGLLKSFTESTAGSASTSATGISGSVSEETELFEPGVLNTG--DGSISTYKDILNLASEVGDPALVYKFMSLAKSSALWSSRKGIAFGLGAIMSKSSLEELLLKDQQTAKKLIPKLYRYRFDPFQAVSRSMTDIWNTLIPESSLTISLYFNDILDELLCGMANKEWRVREASTSALLQLIQ---------------------SQPQEKFSEKMLKIWTMAFRTMDDIKDSVREVGTKFTTVLAKILARSIDVEKGVNPTKSKEILDNILPFLWGPHGLNSDAEEVRNFALTTLIDLVKHSPGAIKPFTPKLIYDFITLFSSIEPQVINYLALNAANYNIDAN-------VIDTQRKNGVTNSPLFQTIEKLINNSDDCMMEEIINVVIKASRKSVGLPSKVASSLVIIILVKRYSIEMKPYSGKLLKVCLTMFEDRNESVNIAFAISMGYLFKVSALDKCIKYSEKLITKYFEPTSTENNKKVVGTAIDSILNYAKSEFDNVASVFMPLIFIACNDE------DKDLETLYNKIWTEASSSGAGTVKLYLPEILNVLCVNIKSNDFSIRKTCAKSVIQLCGGINDSIPYPQIVKLFDISREALSGRSWDGKEHIVAALVSLTEKFS---QTVADNNDLQESINHVMYTEVSRKSMKYVKKILPLYARYINVNPQE-----ETITFLIEKAKEMIRLLG-----SESDDSEGSIKQTSDESTIKRIKPNTEITQKSSKEN--IENEEYVINLLKVSVDICNNSKSRYPMNLLEFIIDEIAYLFHNDRIIHTWR-------------------TQLAASEIGISIVGRFSTISSADFIQNVGRLWDQTFPINCNKET---------------------------IENVKLQMIKFGGLIIQKIPSLQNNIEENLRLLNSIDSTSRIELELKNIGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:. ***. *:: :::: : .**.*::**: * : **. *.. * :: *:.: ::*:**.:*: * : : :::: . * ** :..: * . : . . :: :*: : . * :.:: . : :. : : .**:* . . .:: : . : *:*:: * .*.:*: . : . .*.:. :*.. : : * : : * : :: *:: * :.: : : *:..: : * *:*.*:. : . ..::. * .: . :. : : . : *: : *: : . .: : :*:*:* :. : . :: *: * .: :. :* : : : : .: . : . . . : : : :: * :: : . . : : : : ** .. .: . :. : : . * ::.. . . . : : * . : . . :. .. .* :: . . : . .: : . : : : . * . : : :* : . : :. :: : . : : .::.: . . . : * : *: : :::.*:: . . : : . : ..:* *:* .:***: :: . : :: : :: * .*:: .*: ** *::**.***.:... :..:.. *:. : .. *: :* :* *.. . .::***:: .***::.:* ::*:**.**: * *.*: * ***: : :.: : :::*:****::** : .:* .**::::.: . . * :** ::: .:: : **** :. *: :*:. :: . .: ::* **. ***::..* .. . *.*: . . * :** * *: . *:* .:: *: .: . : . : *. . ** :: . :* :.*:: . : .:*: * ..... ::** :. * .:: :: : . : .:.* :* ..: .: : : ::.* ** : . : : :*. :. * ::*:*. : .. . ** * * : .:.:* . . :. :** *:. :: . ::..:* : ... * ::* : :: : . .:. : * :: :. . *: * :: ..* **:: ***.:: *: .:. .: ..: . * :.. * : . :. : : : : :. . . . . : . * *: . :. : . : . *. :.:* : * :. .. : . . . : . . . . : .: .:: : ::: . * ", "identical_positions": 191, "similar_positions": 569, "identity": "9.09%" }, { "cls_id": "homologset.agr.MGI:2140230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G9L6-1", "uniprot_id": "A0A8I6G9L6_RAT", "id": "A0A8I6G9L6-1", "name": "Calmodulin-binding transcription activator 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWRAEGKWLPKTSRKSVSQSVFCGTSTYCVLNTVP-PIEDDHGNSNSS-HVKIFLP--------KKLLECLPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNS-----SSGFSVEQLVQQILDSHQTKPQPRTHNCLCTGSLGAGSSVHHKCNSAKHRIISPKVEPRAG-GYGG-HSEVQHNDVSEGKHEPSHSR-------------STSREKRNGKVAKPALLHQNSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSSMAVASVMGGLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDAS-QGLVLAVSSDGHKFAFPT-------TGSSDSLSMLPAN-VSEELVLSTTLD-GGRKIPETAMNFDPDCFLNNPKQGQTYGGGGLKAE-----------MVSTNIRHSPPA-ERSFGFTSVLTKEIKTEDTSFEQQMAKEAAYSSSAAAAAAAAAAAASS---SLTLTAG-SSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTG-----HSPHIHQTPSPSFFLQDASKPLPLEQNTHGSLSE---------SGAAFVMPTVKTEASS----------------QTSSCSG--HVETRIESTSSLHLMQFQANFQALAAEGEVTMETSQA-----------AEGSEVLLKSG-ELQTC-------GSEHYLQP-ETNGVIRSAGGVPLLPSN----------------------VVQGLYP--VAQPSLGTTSN-------MELSLDHFDISFSNQFSDLINDFISVE--------GGSGTIYGHQLVS---------GDSAALSQSEDGAR--APFTQAEMCIP-CCSPQQGSLQLSSA--EGGPSTMAYMHVAEVVSAASAQGTLG---MLQQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASN-NYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILERLEQMERRMAEMTGSQQHKQASSGGSGSGGSSSGSGSGGGQAQCAS-------GAGTLGSCFESRVVVVCEKMMNRTCWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQ-----LGQTSRIHCAPS-EEPSTDSWMAQWPREAVSSPEIP------KGVTVIASTNPELRRPRSEPSNYYSTEGHKDYPAPKKHKLNPESFQARQEKLLCTALSLEQPNIR-KQSPRSKQSSPETISPSEGVRGYSREASPPTPETAASQASASQPVVKWSSKDPYIGVSTVQVTGNPKGTSVVKDAAPSQVRPR-EPMSVLMLANREVVNTEMGAYRDRTEHEECSQPMDDIQVNMMTLAEHIIEATPDRIKQETFVPLES-ASERTDPATISSTMSWLASYLADADRLPSAAHIRSAYTEPMTP-SSNASLSPTGSPVSEVAFEKPSLPSAADWSEFLSASASEKVESELAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQE---VAAAVIQRCYRKYKQLTWIALKYALYKKMTQAAILIQSKFRSYYEQKRFQQS-----------------RRAAVLIQNFYRSYKKCGRRRPARR--TAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSP--------------------------LVDHRLYKRSERIEKGQGT----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A891-1", "uniprot_id": "CMTA1_MOUSE", "id": "A2A891-1", "name": "Calmodulin-binding transcription activator 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWRAEGKWLPKTSRKSVSQSVFCGTSTYCVLNTVP-PIEDDHGNSNSS-HVKIFLP--------KKLLECLPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNS-----SSGFSVEQLVQQILDSHQTKPQPRTHNCLCTGSLGAGSSVHHKCNSAKHRIISPKVEPRAG-GYGG-HSEVQHNDVSEGKHEPSHGR-------------STSREKRNGKVAKPALLHQNSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSSMAVASVMGGLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDAS-QGLVLAVSSDGHKFAFPT-------TGSSDSLSMLPAN-VSEELVLSTTLD-GGRKIPETAMNFDPDCFLNNPKQGQTYGGGGLKAE-----------MVSTNIRHSPPA-ERSFGFTSVLTKEIKTEDTSFEQQMAKEAAYSS-------SAAAAASS---SLTLTAAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYASSFSQTG-----HSPHIHQTPSPSFFLQDASKPLPLEQNTHSSLSE---------SGAAFVMPTVKTEASS----------------QTSSCSG--HVETRIESTSSLHLMQFQANFQAMAAEGEVTMETSQA-----------AEGNEVLLKSG-ELQAC-------GSEHYLQP-ETNGVIRSAGGVPLLPSN----------------------VVQGLYP--VAQPSLGNSSN-------MELSLDHFDISFSNQFSDLINDFISVE--------GGSGTIYGHQLVS---------GDSAALSQSEDGAR--APFTQAEMCIP-CCSPQQGSLQLSSA--EGGPSTMAYMHVAEVVSAASAQGALG---MLQQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASN-NYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILERLEQMERRMAEMTGSQQHKQASGGGGS--GSGSGSGAGGGQAQCAS-------GAGTLGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQ-----LGQASRIHCAPS-EEPTTDSWMAQWQREAMSPPEIP------KGVTVIASTNPELRRPRSEPSNYYSTEGHKDYPAPKKHKLNPESFQARQEKLLCTALSLEQPNIR-KQSPRSKQPSPETISPSEGVREYSREAAPPTPETAASQASASQPVVKWSAKDLYIGVSTVQVTGNPKGTSVVKDAAPSQVRPR-EPMSVLMLANREVVNTEMGAYRDRTEHEDCPQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSALERTDPATISSTMSWLASYLADADRLPSAAHIRSAYTEPLTP-SSNASLSPAGSPVSEVAFEKPSLPSAADWSEFLSASTSEKVESELAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQE---VAAAVIQRCYRKYKQLTWIALKYALYKKMTQAAILIQSKFRSYYEQKRFQQS-----------------RRAAVLIQNFYRSYKKCGRRRPARR--TAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSP--------------------------LVDHRLYKRSERIEKGQGT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6Y1-1", "uniprot_id": "CMTA1_HUMAN", "id": "Q9Y6Y1-1", "name": "Calmodulin-binding transcription activator 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWRAEGKWLPKTSRKSVSQSVFCGTSTYCVLNTVP-PIEDDHGNSNSS-HVKIFLP--------KKLLECLPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNS-----SSGFSVEQLVQQILDSHQTKPQPRTHNCLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTG-GYGS-HSEVQHNDVSEGKHEHSHSK-------------GSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDAS-QGLVLAVSSDGHKFAFPT-------TGSSESLSMLPTN-VSEELVLSTTLD-GGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAE-----------MVSSNIRHSPPG-ERSFSFTTVLTKEIKTEDTSFEQQMAKEAYSSS--------AAAVAAS---SLTLTAG-SSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTG-----HSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSD---------SGGTFVMPTVKTEASS----------------QTSSCSG--HVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQA-----------AEGSEVLLKSG-ELQAC-------SSEHYLQP-ETNGVIRSAGGVPILPGN----------------------VVQGLYP--VAQPSLGNASN-------MELSLDHFDISFSNQFSDLINDFISVE--------GGSSTIYGHQLVS---------GDSTALSQSEDGAR--APFTQAEMCLP-CCSPQQGSLQLSSS--EGGASTMAYMHVAEVVSAASAQGTLG---MLQQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASN-NYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILERLEQMERRMAEMTGSQQHKQASGGGSS--GGGSGSGNGGSQAQCAS-------GTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQ-----LGQNPRIHCPAS-EEPSTESWMAQWHSEAISSPEIP------KGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPEYFQTRQEKLLPTALSLEEPNIR-KQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGKWNSKDLYIGVSTVQVTGNPKGTSVGKEAAPSQVRPR-EPMSVLMMANREVVNTELGSYRDSAENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPATISSTMSWLASYLADADCLPSAAQIRSAYNEPLTP-SSNTSLSPVGSPVSEIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQE---VAAAVIQRCYRKYKQ-------YALYKKMTQAAILIQSKFRSYYEQKKFQQS-----------------RRAAVLIQKYYRSYKKCGKRRQARR--TAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSP--------------------------LVDHRLYKRSERIEKGQGT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GTS1-1", "uniprot_id": "A0AC58GTS1_DANRE", "id": "A0AC58GTS1-1", "name": "Calmodulin-binding transcription activator 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAENK--PEGLKKIRNPDRMYRTAVGYTGHVPPKSVSDDTDNNNEHGHLKIYLP--------KKLLECLPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNS-----STGFSAEQLVQQILDSHQTKPPPRTHNCLCTGNLGAGSSLHHKCNSAKHRIISPKVDPRAGGAYSSTHSEVQNNDVSEGKTEHSHSGGKNGRAGGDGAAGAGGREKRNGKVHKPALLHQNSMEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMADSPVVTGMG--HVASVMSSLSQSATVFMSEVSGDPVYSMSPTVDPNAHLLGPDPASSSLVLAVTAESHKFAFAN-AVGLADPASADGLGMLTTAGVSEELVLSSNLETGSIKLPETNMNFDPDCFLNNPKQGQTYGGNGMKTE------ESNGSSCSNGMRCSPPLGDNGYSFNAALVKNIKTEDTSFEQQLAKESGYQVGDAIGAISASSSTNSGQNSLALTPT-GSLLPSGGGLSPSTTLEQMDFSAIDAKQDYPASVIAAASYSQTH--LAHQSHSPSFFLQGSPQ-SQNHQTNSGSTQN------SHDSNAYMGLSVVKTDSSGTNGDFHHHHHTLTNQHTASNCNGGSPTERNNGQAGSLQILQYQNRFASTGQEHEEMSGLEQSTGAEQEGGGIQEKDSDGRMKQGDHLQTGEAEG-VGGAEHYLQQPTETGGVGSGGTSARETGNLCNDTDNNTSNSSHQQLLQGAGLVPGLFSAVGAHQTLTSTGTNGGG--SMEINLDHFDVSFGNQFSDLINDFISVEGGSGTGVVPGSNALYSHQLITHSGTEGQVSSGTAAQQGGDEGAHGARGYNSAELCLQPCCSPQSSQSGAVAA----EAGQLAYMQVAEAVSAAVAHGNMG---MLQATGRLFVVTDYSPEWSYPEGGVKVLITGPWQEASS-EYTCLFDQITVPASLIQPGVLRCYCPAHDTGLVTLQVAASSQIISNSVVFEYKARALPALPSSQHDWLSLDDNQFRMSILERLEQMERRMAEMAGQQQQQGGGGTSESGGTTTGEGGRSNSEQAQFSPIQGQSQGQAPAGSSFESRVVVVCEKMMNRACWAKSKHLIHSKTFRGMTLLHLAAAQGYTTLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHMEAAVVLYKWDRRALAIPDSLGRLPLAIARSRGHTKLAECLESLQREEQQ---SGALTTTPSMPFSPSTEASAAEGWMNVWGAEATSVGLKE-----SNIASSASSSSSDLRRPRSEPSSFYSSVNHGDAPLSKKHKPNPETLQSHPSKSCSAPLGLEEHSHK----PKTCPSKP---------RDSAVEKEQGDGEQSQNKVGSTCGGGRWGSRQAAGRRVSTTGLG--------KERLANRLRLR--EIGSAGTIS------DLRTSQEDLENTGDLQNMN-----MMTLAEEVIEATSDRIKRENFVASDTS-LDGVG---VSSTMSWLASYLGDAERF--------LFNKPLTSSPGLGTVHGGAQPELDGPLGKLGIQSPAEWTALLNASH-NKEERDLTQLALSDPEQRELYEAARQVQNTFRKYKGRPLREQQE---LAAAVIQRCYKRYKQLTWIALKYALYKKMTLAAILIQSKFRSYHEQKKFQQS-----------------RKAAVLIQQYYRSYKELGRPNPRSRATAAALVQHKLRSSLLTKRQDQAARKIMRFLLRCRHR---------------------------AKELKKAKEHENAAKSPVAM---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P5K3-1", "uniprot_id": "A0A8M9P5K3_DANRE", "id": "A0A8M9P5K3-1", "name": "Calmodulin-binding transcription activator 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAENK--PEGLKKIRNPDRMYRSAVCYSAHAPPKSVSDDTETNNEHGHLKIYLP--------KKLLECLPKCSTLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNS-----SSGFSVEQLVQQILDSHQTKPPPRTHNCLCTGTLGAGSSVHHKCNSAKHRIISPKVDPRSG-GYSSTHSELQNNDVSEGKTEHSHSS-KNS----SGSGGGSVREKRNGKVHKPVLLHQNSTEVSSTNQVEVPDTTQNSPVSISSGLNSDPDMADSPAVTGMG--HVASVMGSLSQS--VFMSEVTGDPVYSMSPTGGPNTHIMGPDANPHSLVLAVTSDSHKFAFPGSGSADAGGPGADGLSMLSASSVSEELVLSSSLDSSSIKIPETTMNFDPDCFLNNPKQGQTYGGNGLKQENVASSASSSSTANTNGLQRSPTISDPTYSFSSALVKNIKTEDTSFEQQLAKEGNYQVG---PVVSCSVSNGGGQNSLSLTPA-SSLLPSGGGLSPSTTLEQMDFSAIDAKQDYSTGPTAVG-YTQAMNSLAHQNRSPSFFLQEPPQPSQNQQGRQSSSQKGHMMEHSTPDGTYMGLQVVKTESPGSNGHLHHHHAHQG-QHRP-NCNGGSPTEVQ-GQAGSLQLLQYQGGFPGLGPEHEEVVGMDQSRNVGAGQAGVTENGTDGLLKSGDHLQACSGGGETAGADHFMQQSSENG--AGAEAVALRNGNSTNGP-NNGSQQQLQPLLQGANLVQGLYN---THHGLSGTGANGGGGTGMEISLDHFDISFGNQFSDLINDFISVD--SGATAVGATGTLYTHQLVAPPGSDGTANSGGNQQQGQEDASNRTAGYSSSELCLQSCCSPQSLGGGAGAGGGSGETGSLAYMHVAEVVSAAVAQGTLG---MLQATGRLFMVTDYSPEWSYPEGGVKVLITGPWQEDSS-SYTCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAVSNQIISNSVVFEYKARALPSLPSSQHDWLSLDDNQFRMSILERLEQMERRMAEMAGQQQQ-GSGGTAGTGGGGGGGNGGANSQSQCIS---------GQAGSSFESRVVVVCEKMMNRACWAKSKHLIHSKTFRGMTLLHLAAGQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRALAIPDSLGRLPLSIARSRGHTKLAECLEQLQREEQQQQTPSSLPPASSMSFSPNPDIPTSNSWMVSWASDSMVAPSGQNTGTATTTTNSCSNQNPDLRRPRSEPSSYYSNECQRDLPLAKKHKPNPELVQAQLDKPMSVPLNMEQQTHKLSTSPKTTPSSP---------DKSVSEEGLGTGSIPQIKMSSFRGGHKWSTREGL-RKSSISNMG--------KEKLANRLRQRGESLSMLGIVEREMVNTEMLSYKEDQENQDCLSHMEDLQANMMSLAEHIIEATPERIKREHFPAVESVPLDNSG---LTNTMSWLASYLGDVEHLPSIIHLSPIYSEPLTP-PSNPSLSPGNSPMREGPFEKPTLPAPAEWSEFLRASN-SKVERELAQLTLSDPEQRELYEAARLVQTAFRKYKGRPLREQQE---VATAVIQRCYRKYKQLTWIALKYALYKKMTQAAILIQSKFRSYHEQKKFQQS-----------------RRAAVLIQQCYRSYKEFGRLRPHRRSATAALVQHKLRSSLLTKRQDQAARKIMRFLRRCRHSPLMD---------HRLFKRVSAASAIQVRELRKAREHESVQKSSLTM---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZU4-1", "uniprot_id": "B7YZU4_DROME", "id": "B7YZU4-1", "name": "", "aln": "MENVPDISTSASSSSTSNSTSTLKLQSQITSKNVLIRSQSSGKLSSNEAKSAKPAATTSTTTTLRAAKLKIGAMQQQKQQHQQQHQATSGGNIILLRGTRNENGQIIIQNKQDILSLLSEQQQQQQQEKSHSSTAITLNQLPTATTVARKTIVQGSSGAGSSSSSSSSTISIVANSNNKEASSNTILLQTPINASQLESVLKAQERSKQANATQTKMVERPFMLKHATRSLSSESNCDSKSPFVLQTLKRLEKSQSILVIRNSTASTAATNTSMATSPPNGNSLATSSILSVTRTTKAAKGVAGALHKLKAAAATTATSGGASSAGATSSTATTILRLGKSATTVAINGASKLEATTSTTTAVPVPATATTSNKLSNAVTSEQQQQQQQQSTTTQTNVPLGNDGEPIKLPDNLESLPRADSFPSQRHRWNTNEEIAAILISFDKHGEWQSKEVRTRPKSGSLLLYSRKKVRYRRDGYCWKKRKDGKTTREDHMKLKVQGTECIYGCYVHSAILPTFHRRCYWLLQNPDIVLVHYLNVPYPDDNKMAVIAPSITLWGDKK---EWTKEELVSQLKPMLSTINSDDDSDSGNDIEISTAETVESIVCQLMEKQRLSRQAALVKQLDCGCGDGGCVDGKTCTHPVMRRSAAMLKSSVQ--EKRLGEPFNGNTPNVVVASKLYSR---------------WAERPRQHVDNHGQFHNVTQQLPQESAIKFQIIPPQQQQQQDGNYQQQQYRGGSQMLAARS--NLVMQQQQQHQQQQQYHQQQQQQQQQQQQHQQQQQHLSLQRFVASQGQNSVHLNQQHRLQIAN------------TTITATASDPATTLAAAAAVAAASGATPVALNIMDTELIENQNHMTANKITNSGSSN------------SSSSNASKQLAGQTNNKLNVVNNNDPGNNNFMYNQQQQLNASSNSN------NSSQQQQQQQQQHYYKLQQTTATPTSGQPPPLAQVQPHSLAQPPVEAMCMS--------------PEHRSSSQPTPATSSAGSIPSSVSVSISVST---------STPTPAPTSISTPTSG-----------------TSSTSSSLQSIIDGNQQQQITTTSTAATCDNLMSANALSEQDSHT-----------VNNQATEAPNRSQLQSQ-------SQSLSLNQNGCATYSASSDNSSQISDE------------------------SSSFGGNNQNSSNSSTSEEEPQVEALSFFNETLDLSQEDIQRTLIANMPYNT--------TAAGATAPSTTIT---------TGNTKLELSQQETKEKPAMGTETATEIEDDETDDVFANLDAFDMLVEFPELDLDDKQALNNTALEQSSFLGESAPSQPRKVHNICDFSPEWSYTEGGVKVLVAGPWTSSNGGAYTVLFDAQPVPTQLVQEGVLRCYCPAHEAGFVTLQVACGGFLVSNSVMFEYKLSLLADAP---FDATSSNDCLYKFTLLNRLSTIDEKLQVKTEHELTTDNTA--------------------------------LYLEPNFEEKLVAYCHKLIKHAWSMPSTAASWTVGLRGMTLLHLAAALGYAKLVGAMLNWRSENP-HIILETELDALSQDVYGFTPLAWACVRGHVECSLLLYKWNHNALKIKTQAQQTPLDLASMRGHKVLLAQMYRLEKERCRK--PQLRGGLANLSMNMGVEAEAEEQHQSFSAFDLELQRKHDG----VFLRPVAVHSNQSPPNGSSRYSKRSSIDSGINMDIRSKSGKPLARLHSNFESHDSYALGVDSPLDS--LTGTNCLLSP---------------LRKMDFALCEVSTGESSPVHDKDCDDNSTSATDVTIGN--------DLVLPDAVVGDSDAKVLTLAEHIIAAMPERIKNEADEMMVLGSPLTEPLTSESSALTDSFMDPLLDSLPNTHFDSDFS--------------FDFHDHSYRYHDVSTPCSSLSPASSGPLQSPASYSILG--TDPSVSSPSPPPSTKQLTEFLHASSISS-YPFEADFSKLTLTDTEQRELYEAAKCIQKAYRSYKGRQKLEEQNKERSAATVIQNYYRRYKQ-------YAYYRQMTNAALVIQHGYRSYRRNKRFKKSGLCLSSSSDHGSVSSNSQCLSSFYDHYKQDQQQLHELGSQPSTPKETSPSGPLKRTYSQSTQNQAARKIQQFMRQSRIKLQKERAEKEKLVHQRRAEYLQNLQFQGQQEMLVYHENNISAPSSGNTNASNNNNLHQIQSNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* . . :: :. . .:: .. : :: * . **.**:..::*.:************ **:*:** ** :.. :***:.**::**.****:**:*************************.**:*******:*:************************* :* . . :: *** :******:.*****: *: ..... *:. :.*.:* *:::.:: . . : * * ..* :.*. . * :. :.. . .: * . . :. *: . :* : :*: : ::.. . ::. . .. . ... :.: .* ::. . :. *. : .: : . : : . . : *:: :. .: : *. :: : .. * : :*.: : *: : . .. . : :.. . : :. . :: .:: ::** :. . .: . . : *:.* .* : :: .:: : : *:. * . .. * . . :.* :.. . . .. . .: . .:: :. . .**: . . :: .. . .: . : : :. :.: : :*:* : ** :: .:.: :: . . :: :. ..:. : : . .:* :. : . . ::. : *:******.*******::*** . .. *: *** .**:.*:* **********::*:****** .. ::****:**** *. * .* * :* :::::*:**. ::.:: : : . . **.::*. *.*::.:: *. : :**********. **:.*: ::::**:::. * ** *:*.*. * :. *** ***. **:*.:::****::.*: * . : ** :* *** * : *:::. . : . : : : : . . . *. *. * : .* .::. .. .*.::. . * . . . : . . .. : : . : :*:: .::. : : . * . : :.: : . *: . .. : .* . . ::: * * ::::*:*:* *********: :*.::*.**** *:*: *::***. *::*** ** *::** **::** :*** .:*:*::* : : : :: :. :: . . . *: : . *:****** :*: :.* : :. : . ", "identical_positions": 325, "similar_positions": 481, "identity": "14.22%" }, { "cls_id": "homologset.agr.MGI:2140248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1H9T6-1", "uniprot_id": "ZBT48_MOUSE", "id": "Q1H9T6-1", "name": "Zinc finger and BTB domain-containing protein 48", "aln": "MD--GSFVQHSVRVLQELNKQREKGQYCDATLDVG-GLVFKAHWSVLACCSHFFQRIYGDGTGGSVVLPAGFA-EIFGLLLDFFYTGHLALTSGNRDQVLLAAKELRVPEAVELCQSFQ-PQTSVGQAQ---SGLGQPASQDVKSHLKEPTDLDEEEVFRTLSLASV-DQEPR---DTEQPQLGTPAQST-TAFLCGKLTQALKP---------SPSEDKESED-CKEPPRPFEAGGAPLQGESNEWEVVVQVEDDRDGD--YVSEPETVLTRRKSK--VIR----------KPCAAEPALGAGSLTAEPTDSRKGAAVP-------VECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRLHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGE---RPFSCEFCEQRFTEKGPLLRHVASRHQEG-RPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDE--------------------KMVVVALQPPADLEVGSAEVIVESLTQGGLASQLPSQRLCSEES------FASPGVLEPSLII----------TAAVPEDCDT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V777-1", "uniprot_id": "G3V777_RAT", "id": "G3V777-1", "name": "Zinc finger and BTB domain-containing protein 48", "aln": "MD--GSFVQHSVRVLQELNKQREKGQYCDATLDVG-GLVFKAHWSVLACCSRFFQRIYGDGSGGSVVLPAGFA-EIFGLLLDFFYTGHLALTSGNRDQVLLAAKELRVPEAVELCQSFQ-PQTSAGQAQ---SGPGQVSSQDVKSHLKEPTDLDEEEVFRTLSLASV-DQEPR---DGEQPQLSTPAQSS-PAFLCGKLKQVLKP---------SPPADKESED-SKEPPRPFEAEGAPLQGESNEWEVVVQVEDDRDGDGDYASEPETVLTRRKSK--VIR----------KPCAAEPALGAGSLTAEPTEGRKGAAVP-------VECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGE---RPFSCEFCEQRFTEKGPLLRHVASRHQEG-RPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIDDE--------------------KMVVVALQPPADLEVGSAEVIVESLTQGGLASQLPSQRLCSEES------FASSGVLEPSLII----------TAAVPEDCDT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10074-1", "uniprot_id": "ZBT48_HUMAN", "id": "P10074-1", "name": "Zinc finger and BTB domain-containing protein 48", "aln": "MD--GSFVQHSVRVLQELNKQREKGQYCDATLDVG-GLVFKAHWSVLACCSHFFQSLYGDGSGGSVVLPAGFA-EIFGLLLDFFYTGHLALTSGNRDQVLLAARELRVPEAVELCQSFK-PKTSVGQAAGGQSGLGPPASQNVNSHVKEPAGLEEEEVSRTLGLVPR-DQEPRGSHSPQRPQLHSPAQSEGPSSLCGKLKQALKP---------CPLEDKKPED-CKVPPRPLEAEGAQLQGGSNEWEVVVQVEDDGDGD--YMSEPEAVLTRRKSN--VIR----------KPCAAEPALSAGSLAAEPAENRKGTAVP-------VECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPHVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGE---RPFSCEFCEQRFTEKGPLLRHVASRHQEG-RPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDE--------------------KMVVVALQPPAELEVGSAEVIVESLAQGGLASQLPGQRLCAEES------FTGPGVLEPSLII----------TAAVPEDCDT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDZ5-1", "uniprot_id": "E7FDZ5_DANRE", "id": "E7FDZ5-1", "name": "", "aln": "MEKLAEGSSHAQRVLSLLNKQRAFGHFCDAMLCTASGQVHLAHRNVLACFSQLFQEPTSKTPSIKFDLPLECPDDGLELLLNFFYTGDLQLDDSNLEKVQNAASGLSVPVFLIPCQGIKTPDLNEGDPS---KPLLSEPQPDQTPNKKTRSGQRTKNKADAFKLSTASDDEPP--ALKSTTVTRSGRRVKGPSRLVGESQISVVTRLGVGRRKASFVEDKEQETGATEDGDHPRHEDASETTQTTEVDISVDDQNDDDDDVEDAANNDDDSDRGGSVDIIIEGTDEEYVPHDSPCSSTKTP-RGKRKEKSSNKKNGEGTSKDSKKGAVQCPTCHKTFLSKYYLKVHNRRHTGEKPFKCGKCGKCYFRKENLLEHEARNCLTRTELVFSCSKCSMTFKKRQELRHHTVMHTGVMPNKCTSCPEQFMQKRDLKIHMIKVHGAPKPHACPLCPKCFLSRTELRLHEASKHRGEKLFVCEECGHRASSRNGLQMHIKAIHRNERPFVCQLCNHAFTQKANLSMHLRTHTGEKPFQCHLCGKTFRTQASLDKHHRTHTGE---RPFSCEFCEQRFTEKGPLLRHIASKHQEG-RPHFCQICNKTFKAIEQLRVHVRRHKGMRKFECTLCGYKFTRQAHLRRHTQIHNRMENYSPRQRRLRNLVVEDASAAAASSGLPVQTEAQAEPADIVSIVIQQEGAAETG-GEQASYPVTDGAVNAEQTGFALAEREDGVAQTEFTVADVMEQTLLVRVQEAYPIHQSDVVVEIPNTEADRKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPA2-1", "uniprot_id": "Q9VPA2_DROME", "id": "Q9VPA2-1", "name": "C2H2-type domain-containing protein", "aln": "--------------------------------------MENSARIVYVCSLCLRQYDLQEDLRG----------------HLVYFHGYEPISTP------------------------------------------SVKNKTAKTSTKEQTAAGSNSQDKQTVVERSENSEPP-----------------------------------------------------ASELQPMPFKDFRLVLRANMLEPCSFG-----------------------------------------------------------------------------KECPFKFQDATKMELHCSCHKGG-SFSCCECG-----------MELPNWRRCSAHLWKAHQVDVDLLVCPVFECNYKSPISALVWRHMQVHKKWRPRVLRSLAAVQRRRKLKEQSAEMAAQPAALPPSSKKNKYYAEK-----TCEICNRKFVNGKTLSKHVKTVHNKIKPFICNVCGKKTARKASLIIHMRQHTGEKPLQCGECKFSTRDPSVLHKHRQRHDSQDTRSSLKCSQCDYFCIQANALKRHMRLNHAEAYRDLCCDICSFTSINVERLRAHKQDHRQGLITNCEDS--MDARAAGFKYPRKVGDKNGEISAD--CFMPLESVDS--------------------------LPHEPALDTGGVTIPAPPSEDTQFPTYLKD-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .* : * . .:: * : . .. * : :. : :.** . :. : * .* . :::* *.* .*.* :** * * : ::.. . : :. : . : : . ::: : . :: : * ::. ..: .. : :: .: .** *.:: . : *. *:*: *.: :*.:*:.*.: ::**.* :*:* ******:** * : * : *.**.: * .: .:.*. *: : ..* **: .* *. * *:**. * :*:**.* : *: :* . :* * :: :: :: : .. : * * : :.* . : . : . ", "identical_positions": 71, "similar_positions": 136, "identity": "9.21%" }, { "cls_id": "homologset.agr.MGI:2140259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQZ3-1", "uniprot_id": "A0A8I5ZQZ3_RAT", "id": "A0A8I5ZQZ3-1", "name": "", "aln": "MNVIYPLAVPKGRRLCCEVCEAPAERMCTACTVTYYCGPVHQKADWGSIHAKICQLLIPLRTSMPFFNSEEERQHGLQQLQRRQEHLIEFCYTVAQKYLFEGRHEDAVPAALHSLRFRMNVHGLSSVELVPAYLLLAEASLGLGRIVQAEEYLSQAQWTVLKSTDCSNATHSLLHRNLGLLYIAKKNLEEARYHLANDIYFASCAFGTEDVRTSGGYFHLANIFYSLKKMELADTLYTKVSEIWYTYLSSHYQALLHARTQQTDLLGKQFMNDTGLDEAQEAEAIRILTSILIIQESTSTQAPQKGILILKTLGILYYLMLEFSKAKEYATKALSLA-EVYLSEEEQGVIQELLSAILAEEKQLTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BGJ5-1", "uniprot_id": "ZMY12_MOUSE", "id": "A2BGJ5-1", "name": "Zinc finger MYND domain-containing protein 12", "aln": "MNVIYPLAVPKGRRLSCEVCEAPAERMCTACTVTYYCGPVHQKADWDSIHAKICQLLIPLRTTMPFYNSEEERQHGLQQLQRRQKHLIEFCYTVAQKYLFEGRHEDAVPAALHSLRFRMNVHGLSSVELVPAYLLLAEASLGLGRIVQAEEYLSQAQWTVLKSTDCSNATHSLLHRNLGLLYIAKKNLDEARYHLANDIYFASCAYGTEDIRTSGGYFHLANIFYGLKKMELADTLYTKVSEIWYTYLNSHYQALLEARSQQTDLLGKQFVNDTGLDEAQEAEAIRILTSTLIIQESTSTKAPQKSILILKTLSILYYLMLECSKAKEYAMKALSLA-ETYVSEEEQRFIQELLSVISAEEKQP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0C1-1", "uniprot_id": "ZMY12_HUMAN", "id": "Q9H0C1-1", "name": "Zinc finger MYND domain-containing protein 12", "aln": "MNVIYPLAVPKGRRLCCEVCEAPAERVCAACTVTYYCGVVHQKADWDSIHEKICQLLIPLRTSMPFYNSEEERQHGLQQLQQRQKYLIEFCYTIAQKYLFEGKHEDAVPAALQSLRFRVKLYGLSSVELVPAYLLLAEASLGLGRIVQAEEYLFQAQWTVLKSTDCSNATHSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKLDLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFVLKILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTIQELLSLISTEDHPIT-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************.**********:*:********* *******.*** ***********:***:**************:**::*******:********:*********:*****::::******************************* ********************************* :****************:****:**************.***::*************::**..***.* .*: ** ***** * ******************* * *:**** :**** *::** * ::****:: ***:**. :***** * :. .** ****** * :*:: ", "identical_positions": 291, "similar_positions": 46, "identity": "79.51%" }, { "cls_id": "homologset.agr.MGI:2140260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W65-1", "uniprot_id": "PCSK9_MOUSE", "id": "Q80W65-1", "name": "Proprotein convertase subtilisin/kexin type 9", "aln": "MGTHCSAWLRWPLLPLLPPLLLLLLLLCPTGAGAQ-DEDGDYEELMLALPSQEDGLADEAAHVATATFRRCSKEAWRLPGTYIVVLMEETQRLQIEQTAHRLQTRAARRGYVIKVLHIFYDLFPGFLVKMSSDLLGLALKLPHVEYIEEDSFVFAQSIPWNLERIIPAWHQTEEDRSPDGSSQVEVYLLDTSIQGAHREIEGRVTITDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGPLVVLLPLAGGYSRILNAACRHLARTGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGKDIIGASSDCSTCFMSQSGTSQAAAHVAGIVARMLSREPTLTLAELRQRLIHFSTKDVINMAWFPEDQQVLTPNLVATLP-PSTHETGGQLLCRTVWSAHSGPTRTATATARCAPEEELLSCSSFSRSGRRRGDW-IEAIGGQQVCKALNAFGGEGVYAVARCCLVPRANCSIHNTPAARAGLETHVHCHQKDHVLTGCSFHWEVEDLSVRRQPALRSRRQPGQCVGHQAASVYASCCHAPGLECKIKEHGISGPSEQVTVACEAGWTLTGCNVLPGASLTLGAYSVDNLCVARVHDTARADRTSGEATVAAAICCRSRPSAKASWVQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59996-1", "uniprot_id": "PCSK9_RAT", "id": "P59996-1", "name": "Proprotein convertase subtilisin/kexin type 9", "aln": "MGIRCSTWLRWPLS----PQLLLLLLLCPTGSRAQ-DEDGDYEELMLALPSQEDSLVDEASHVATATFRRCSKEAWRLPGTYVVVLMEETQRLQVEQTAHRLQTWAARRGYVIKVLHVFYDLFPGFLVKMSSDLLGLALKLPHVEYIEEDSLVFAQSIPWNLERIIPAWQQTEEDSSPDGSSQVEVYLLDTSIQSGHREIEGRVTITDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGPLVVLLPLAGGYSRILNTACQRLARTGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGKDIIGASSDCSTCYMSQSGTSQAAAHVAGIVAMMLNRDPALTLAELRQRLILFSTKDVINMAWFPEDQRVLTPNRVATLP-PSTQETGGQLLCRTVWSAHSGPTRTATATARCAPEEELLSCSSFSRSGRRRGDR-IEAIGGQQVCKALNAFGGEGVYAVARCCLLPRVNCSIHNTPAARAGPQTPVHCHQKDHVLTGCSFHWEVENLRAQQQPLLRSRHQPGQCVGHQEASVHASCCHAPGLECKIKEHGIAGPAEQVTVACEAGWTLTGCNVLPGASLPLGAYSVDNVCVARIRDAGRADRTSEEATVAAAICCRSRPSAKASWVHQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBP7-1", "uniprot_id": "PCSK9_HUMAN", "id": "Q8NBP7-1", "name": "Proprotein convertase subtilisin/kexin type 9", "aln": "MGTVSSRRSWWPLP----LLLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLAEAPEHGTTATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTKILHVFHGLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALP-PSTHGAGWQLFCRTVWSAHSGPTRMATAVARCAPDEELLSCSSFSRSGKRRGER-MEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAEASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEGAVTAVAICCRSRHLAQASQELQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2J6-1", "uniprot_id": "E7F2J6_DANRE", "id": "E7F2J6-1", "name": "Proprotein convertase subtilisin/kexin type 9", "aln": "MRSVVSVCC----------LGFLLGLLAVVECDEDYIEDED--EMILSLILQDD-TQPEAENRPSAQFYRCTKDAWRMPGQYLVVMRNGTHVNQVERTTRRLSAKAAKRGYLIEILQTYSGAFRGFLVKMSSDVLHMAVKLPHVEYIEEDSSIFAQSIPWNLQRVLQNKHEAGKYSPPNDGAKVGVYLLDTSVQLTHREVEDRVMVTDFNRVPEEDGVRVHRQASQCDSHGTHIAGVISGRDSGVARGASVNSVRVLNCQGKGTVSGALAGLEYIQSSLASQPVSPVILLLPFVGGFSRTLNTACRKIVESGAVLIAAAGNYNDDACLYSPASEPEVITVGAVNFADQPLNRGTTGTNVGRCVDVFAPGDDIISASSDCPTCFTTKSGTSQAAAHVAGVAAVLLNLRPNSSSAEVLQQLRYHSVKQVINPESLPVMHRLTTPNMVVALPDPTSTLTGEDLLCRSVWSERSASPVFSTAVSRCRSTEEMLSCSSFSDNGMRAGER-VEERDGQKECVAVNVNGGPGVFAVARCCTGHRAQCQMLEGPERGAGAECPP-----EHHLTGCSFSSSSGEASDSDRTLHGSRR---TCAAKKGMMSYAFCCHTSTLECRLKEHHLNTLSQQVEVSCEDSWTLTACEALSRDAVIHGAFAMGNTCVVRTSGVDKD-------AAAIATCCRNHPLHGTQDH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09232-1", "uniprot_id": "PRTB_YEAST", "id": "P09232-1", "name": "Cerevisin", "aln": "MKLEN--------------TLFTLGALGSISAALVIPNLENAADHHELINKEDHHERPRKVEFTKDDDEEPSDSEDKEHGKFHKKGRKGQDKESPEFNGKRASGSHGSAHEGGKGMKPKHESSNDDDNDDKKKKPHHKGGCHENKVEEKKMKGKKVKGKKHHEKTLEKGRHHNRLAPLVSTAQFNPDAISKIIPNRYIIVFKRGAPQEEIDFHKENVQQAQLQSVENLSAEDAFFISTKDTSLSTSEAGGIQDSFNIDNLFSGYIG--YFTQEIVDLIRQNPLVDFVERDSIVEATEFDTQNSAPWGLARISHRERLNLG--SFNKYLYDDDAGRGVTSYVIDTGVNINHKDFEKRAIWGKTIPLNDEDLDGNGHGTHCAGTIASKHYG--VAKNANVVAVKVLRSNGSGTMSDVVKGVEYAAKAHQKEAQEKKKGFKGSTANMSLGGG-----------KSPALDLAVNAAVEVGIHFAVAAGNENQDACNTSPASADKAITV-GASTLSDDRAYFSNWGKCVDVFAPGLNILSTYIGSDDATATLSGTSMASPHVAGLLTYFLS----------------------------LQPGSDSEFFELGQDSLTPQQLKKKLIHYSTKDILFDIPE--DTPNVLIYNGGGQDLSAFWNDTKKSHSSGFKQELNMDEFIGSKTDLIFDQVRDILDKLNII-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25036-1", "uniprot_id": "YSP3_YEAST", "id": "P25036-1", "name": "Subtilisin-like protease 3", "aln": "MKFST--------------ILPILWAN--CCLCMIIPDFDGIVRFIENID------------------------------------------------GTRSVR-------AGEGLG-----------------QHDPGNFHT-----------------EHQHVAHK---------------------TEFLPYRYVIVFNEDISLQQIQSHMQVVQKDHSTSVGKLTENDAFWRVISSSVSSKSQFGGIDNFFDINGLFRGYTG--YFTDEIIKIISQDPIIKFVEQETTVKISNSSLQEEAPWGLHRVSHREKPKYG--QDLEYLYEDAAGKGVTSYVLDTGIDTEHEDFEGRAEWGAVIPANDEASDLNGHGTHCAGIIGSKHFG--VAKNTKIVAVKVLRSNGEGTVSDVIKGIEYVTKEHIESSKKKNKEFKGSTANLSLGSS-----------KSLAMEMAVNAAVDSGVHFAIAAGNEDEDACLSSPAGAEKSITV-GASTFSDDRAFFSNWGTCVDVFAPGINIMSTYIGSRNATLSLSGTSMASPHVAGILSYFLS----------------------------LQPAPDSEFFN---DAPSPQELKEKVLKFSTQGVLGDIGD--DTPNKLIYNGGGKKLDGFW-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25381-1", "uniprot_id": "RRT12_YEAST", "id": "P25381-1", "name": "Subtilase-type proteinase RRT12", "aln": "MKPQC---------------ILISLLVNLAYAEEYLVRFKNPTAFQQFTS--------------------------------------------------------------------------------------------------------------------------------------------NSNRSWRQFIDNKIEKKFSIGSFRGVTMNLSKNLVNKLKKSPLVADIVPNFRFEAFEGDSVN---SAESSYTFNATAKYSYEDVEEEQNITYQPDAPRHLARISRHYQLPFDVGDKDRYKS-----------WFNYYYEHDYQGQDVNAYIMDTGIFADHPEFEDRVIQGIDLTKEGFG-DQNGHGTHVAGLVGSKTYG--AAKRVNLVEVKVLGKDGSGEASNVLSGLEFIVEHCTKVSRPQGKK---CVANLSLGSF-----------RSPIINMAVEGAIEEGIVFVAAAGNFNLDAYWASPASAENVITVGAFDDHIDTIAKFSNWGPCVNIFAPGVEIESLSHLNYNDTLILSGTSMSTPIVTGVAAILLSKG-----------------IEPEMIAQEIEYLSTRNVFHRRTLFFKPSTPNQILYNGVDKLDDPYDDETFPRLNIEAIAKELEEYNATLQTPMSENLQSGSKLWGWNNDVTLPLGEIRLKRRDFMKNL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . . . . . . .: : : . : . . * : . . * : * . .:. . :: .* .. : . :* ::: . : ..* . : ... . . : : : . .. . . . * .::* . :. *: :: : .. ", "identical_positions": 10, "similar_positions": 68, "identity": "1.43%" }, { "cls_id": "homologset.agr.MGI:2140279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1R4-1", "uniprot_id": "TDRD7_RAT", "id": "Q9R1R4-1", "name": "Tudor domain-containing protein 7", "aln": "---MLEADLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVVRIEASRSGEIVCYAVACTETARIAQLVARQRTSKRK-TGRQINCQMRVKKTMPFFLEG---KPKATLRQPGFASDYSIS---KKPNPTLLREKGSTLGAKADVDMPP--------------YPDAPVQRHVSMSANSSVTVLRSHPEASKLQFMGYSPKPHCLLLFSPKSSLPAPFQTHISR---------ACPKEVNDNLNQTVEKPNVTPPASYTNKMDEVQNRIKEILDKHNNG--IWISKLPHFYKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGG-QDLLLYPAKREQP----------------------------------------LRSDQDPEKERPPPPPA-----------PRQEVPSKGSPAVMP-----------DVKEKVAELLGKYS---------------------------SGLWASALPKAFEDMYKVKFPEDALKNLASLS----DVCTINY-ISGNTQKAILYAKLPLPTDKILKDEAQAQGDFDIKSMIEQEYLQIEKNMAESADDFVEDITVPPLVIPTEASPS-----VLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEYYSRNPRVTPIQTVHVGQLLAVNAEE-DAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSFQATKCKLAGLEILNDDPNLVKVVESLTCGKIFAVEILD--------------------KSDIPLVVLYDTSGEDDININATCLKAICDRSLEVHLQVD---AMYTNVKVTNICSDGTLYCQVPCKGLNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKICLFHCKG--KWLRVEITN---VHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDEARGVAYVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAVSAAASSPGNRNASTPAP-----GSPAESLRKSHPEVLRKSVLDHTSSFSLEELPPPVHLSKSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEMILYYSVSEER---HIAVERDQVYAAKVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDVFRKLPFQAVTAQLAGVKCS--QWSEEASMVFRNHVEKKPLVALVQTVIEHANPWDRKVVVYLVDTSLPDTDTWIHDFMSQYLVELSKAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1H1-1", "uniprot_id": "TDRD7_MOUSE", "id": "Q8K1H1-1", "name": "Tudor domain-containing protein 7", "aln": "---MLEADLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVVRIEASRSGEIVCYAVACTETARIAQLVARQRTSKRK-IGRQINCQMRVKKAMPFFLEG---KPKATLRQPGFASDYSIS---RKPNSALLRDRGSALGVKADVDMPP--------------YPDTPVQRHASMSANS---------------------------RFSPKSSLPASFQTHISR---------ACPTEVNDNLNQTVEKPNITPPASYTNKMDEVQNRIKEILDKHNNG--IWISKLPHFYKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGG-QDSLLYPARREQP----------------------------------------LKSDQDPEKELPPPPPA-----------PKQEVPSQGSPAVMP-----------DVKEKVAELLGKYS---------------------------SGLWASALPKAFEDMYKVKFPEDALKNLASLS----DVCTINY-ISGNTQKAILYAKLPLPTDKILKDEGQAQGDFDIKSMIEQEYLQIEKNMAESADEFLEDITVPPLVIPTEASPS-----VLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEFYSKNPRVTPIQTVHVGQLLAVNAEE-DAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSFQATKCKLAGLEVLNDDPDLVKAVESLTCGKIFAVEILD--------------------KSDVPLVVLYDTSGEDDININATCLKAICDRSLQVHLQVD---AMYTNVKVTNICSDGTLYCQVPCKGLNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKICLFHCKG--KWLRVEITN---VHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKMDETKGVAYVYLFTPNNFPDPHRSINRQITNADLWKHQKDVFLSAVSTAASSPGNRNGGTPAP-----GSPAESLRKSHPEVIKKSVLDHTSSFSLEELPPPVHLSRSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEMILYYSVSEER---HIAVERDQVYAAKVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDVFRKLPFQAVTAQLAGVKCS--QWSEEASMVFRNHVEKKALVALVQTVVEHTNPWDRKVVLYLVDTSLPDTDTWIHDFMSQYLLELSKVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHU6-1", "uniprot_id": "TDRD7_HUMAN", "id": "Q8NHU6-1", "name": "Tudor domain-containing protein 7", "aln": "---MLEGDLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVVRIETSRSGEITCYAMACTETARIAQLVARQRSSKRK-TGRQVNCQMRVKKTMPFFLEG---KPKATLRQPGFASNFSVG---KKPNPAPLRDKGNSVGVKPDAEMSPYMLHT---TLGNEAFKDIPVQRHVTMSTNN---------------------------RFSPKASLQPPLQMHLSR---------TSTKEMSDNLNQTVEKPNVKPPASYTYKMDEVQNRIKEILNKHNNG--IWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGG-QDLLLYPAKRKQL----------------------------------------LRSELDTEKVPLSPLPG-----------PKQTPPLKGCPTVMAG----------DFKEKVADLLVKYT---------------------------SGLWASALPKAFEEMYKVKFPEDALKNLASLS----DVCSIDY-ISGNPQKAILYAKLPLPTDKIQKDAGQAHGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPS-----VLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEE-DAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTCGKIFAVEILD--------------------KADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVD---AMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKG--KWLRVEITN---VHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMS-----GNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEER---HIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKCN--QWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NAF9-1", "uniprot_id": "TRD7A_DANRE", "id": "A6NAF9-1", "name": "Tudor domain-containing protein 7A", "aln": "---MSDVELVKKMLRAVLQSSKHGVAMARLQGDYRALTGEMIPFRKFGHDTLESFLRSIPGVVRLERSITGEVMCFAGVCEETAHIAQLVARQKNVKKTGCSKLLNFQMRARTSHLFSHNV---KPRLSLRQPSNMTHPGRG---SVTSFYSTQR------KLYSNDLPS---------------SRAPAWQMNRK---------------------------------SPVPEKTSVVPSKIN-------------TNIKTPLKKTSGTAAQQKPVNR-ADVELVQGRIKQLLQKYSSG--VWLSKIPQLYKSMFQEELH--IIQEVEKWTHICTVEKPGSNNIVDRLVYPVLEPVPKASPVPVKSPCKQSPNTALLKQPTLTQKTTRTFRTLAINIPQSTPKPQTPLSPTSPNSTMIDFTLSETPKTQSLSPITPPSTPPAHQ---PLTTELKQKLRQLLNKYS---------------------------QGLWAHGLPQLFQEAFGCAFPQYVLEDLSLLA----DTCMVEYPMPDNRKRAILYTLP-------------CQVQTQPRSRPPPLVLPCT-----------SNPHVPPLIIPTADFHS-----VFVIEINSTNNVVVRFAGGGYSKSLEVMEEEMQNFYNNIGAGLCLLSPKIGQLVAVASSD-GAMLRAQVHQLSEDKVKVYFLDHGFFDLVSRKTLFQLRDQFMTLPFQATTCQLAGLEPFSTDPVVLKTLQSLAVGRSLLAEIVE--------------------REDTPLVVLYDTSENDDVNVTAMCLKALQDKSMENPLQVN---SVYTNVCVTNVCSDGSVYCQLPSRGQAKLKDIMDKIEAHFIS-QLTWELLVSRPFCGKVCLAKYKG--KWARAEIIN---LHGSHVLDILFLDLGLPASLEVSELREIPPIFLKELITIPPQAIKCLLEDLNVDRAVWPPEAVLWLRETVHNKAPSCMKIVKLDETR-TVHIYLFCGNEAQDIHDSVNRQLASCPFW--KQDVYANKINKASELFLPDAGE----------------PSGSSP----------APSNALTLPPQLNLPLVGQNMDVFVSVACHPGHFVLQPWQDLYKLVVLMGEMVLFYNKQEVT---TVDIQKNNVYAAKIDNNWHRVLVKGLLTNGLVSVYELDYGKYELINYTQLQPLIEEFRQLPFQGISAQLADVKKE--VWCEEASMVFRNHVEKKPLVAQIESVEEGEWPWERKISVYLVDTTQENKDIWIHNIMKEFLDEISRDA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FDW8-1", "uniprot_id": "TRD7B_DANRE", "id": "E7FDW8-1", "name": "Tudor domain-containing protein 7B", "aln": "---MADEELVKKMVRAVLQSSKSGLSLSDLQVEYKDLTGELIPYKQLGYVTLDALLHSMPSIVKLDKGQSGEVMCHATTGNEMAHITKLAARQRTAKKTGRPQVVNCQMRVKPAAPLVLNA---KPRTSLRQPDHRGRLGRG---GGRGHGDTRTGCMRDPQLDGKGGRP---------------HNTPPNTPSRKPSLP-----------------------------SERPEKRMTLPSRFQKEVHAHILRNPQHINVPSNLNENTTPPKPRLPHSAPYSPKLVQSRLQEVLNKHSNG--LWVSKLPQLYREHYKQDLPSEALKELENWTHICTVEKPCSSKPQELLLYPAKETS------------------------------------------QITPTPTHDRSPSHHK----------KPQTQRPSLTAKSNTPESPK---ALSPDLKQKLGELLLKYS---------------------------SGLWAHALPKLYQDTYKCKLPEFVLDQLTLLS----DICTIDYPVPDNPKRAILYAKV-------------VEDENRNQSGLAGQEMKLER--------RLSSQTVPPLVIPRVEYPS-----VLVVDASDTNCVILRYIGEGYSKAQEKLEDEMREFYRQDNTKMALRSPSPGQLTAVGAEEEDDIIRAQVCEVMADKVKVYYVDHGFSEVISIRKLFELNEKFYRLPFQATKCKLAGLESFSQEQAVLKKLESIATGKILLAEILE--------------------REDMPLVVLYDTSQDDDVNINAACMKALQDRSLESPLKVN---SAYMNVSVTSVCSDGTIYCQVPSRGLTKLNEILEKTENYFHS-QVTSESLVSRPFCGKNCLARYKG--KWSRVEITN---LHGSRVLDILFVDVGVQASVEVIELREIPPPLLRDLISTPAQALKCCLAGLPVSVGLWTPDAVQWLRDTVLHISDCSLKIAKVDETKRLAHVYLFTSKNFHDTSCSLNQQLADSDLWNHQKDVFLSSRGPLKSLNVPTATQTSSLKTDR-GDKALHTPKKTSPPLGSKSTPAGSPPERLSLPPALELPEIGQNMDVFVSVACHPGHFVLQPWQDMYKLVVLMGEMILHYNKMEEK---ALKVEKNQVCAAKVENNWYRVLVKGVLTNGLVSVFQLDYGKHELVSGTKLRPLTQEFCQLPFQAITAQLAGLKPR--QWSEEASIVFRNHVEKKPLVAQLESVQEASQPWERKVMIYLVDTSQEERDIWLHDIMAEFTDEMTKTA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E910-1", "uniprot_id": "Q0E910_DROME", "id": "Q0E910-1", "name": "", "aln": "MEKQEVLEYVAKVVRALITSAKPPVTLRSIVADYMEIEGEPIPFRRLGYSNDQELLKDSNQFNFHQSG--NQVFITAKYNANTEHIVRMVRQQKTSKSTSLSKPTPIAQKPKPIAQKHTHGNKYHYQQRNKQPNHQPDQEIGRAAKCENQAIAEHKQDLTGIITQELFESFNNIQGPFSENLQVFNKNPEYITRRKKELK---------------------KEDDLDRGQITKEVAREKQKEKETRDRAVTETIFVTIENKKAPVMNGHGPRHVKVANGQDKHNDGKPPLRAILGNSASQRQQDTSTVYHSPESSFKRPRHPRVMYPGHQRTTGVSVNHRLKVTPQSDAPTPAVAPITPPASP---------------------------------EYAQTTTAAKATYKEDIHGGQGETGNVVTNPKVKVPLKFDPSLDPVSTLNFYCAANDFEKPAYNIFNKLRNLHCSVQIAGDVYSSYPQEFTDKETAYQRTAQIAIQRIMHAQSHQKLSACTFSDVEFIDGLYKELLKHPHGILGHKLEDWYGSTFRQHLPSHWYDLIVKSNKIRVEHGIDPRIILFANDPGSSEPDRTSITTLPQMVLPWQSSEGGSHDWNMFISFCDSTKIVWARMIDQIANFEELTKHIGRQMESP-HFRQKVSKPYAQEVYLVEMPDGWNRVRAISVDEETRSGRYHFIDFGDVAMFHSEDLFHCPPQFLALPAQAVCLSMYALDKFEDHPHALQVLTKELDGQTVVAHVLTTEKQFLELGGSAQGVVENGKRRACLVATLYDTSTAEDIHLNDLVAKRITKCTPAPSLSDEKKIGKTTPILVSHINDDGDLMVLLRNDDLKFVERSIAQTVADLGEQDRVSYSDLLHDRHIFVCDETVDGVKQWFRGRLVTRPLNPDEESFDVYYVDDGRQRKAHISNIYRLEAN-NRALATFPPQAIPVRLHDVPEIG----GHMLHRLRGLIPWRTEALLKVVAMDGGKPLVNVFIREDPESMYMCVNIGLRLELEMASSIHPEKYDHTLLSSNVQLPRRGSFSSVFSNQSSSSDLVATTPPVTPEKKPSARSTGSTFSSLMLKDYEAIPAVGAYFEVRVALSVNPGHFAVQPYKYYNQLQTLMKNLQEHCQKTAAKGVQPSQLAIGEAYAAPDSEGVYHRVSIHKIYDEIIHVRFVDVGDDGVIACDQLKTLNPELRKLPKMALPAQLYGIQLTDVVWSKENCVRFRELSLGQKFIGIVRRMTKQKD-GGRALCLELVDTSTP-KDIKLHEILINEKHAQPAT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *::**:: * * : : : :* : *: **::::*. . : *:. . : . .:: * : :*.::. :*:. * . : : : . : : :**. . . . . * . . . . : . . . . . : :: :* : . *.: : .. ::. : .: . :*:: . *. : . *: . . :.:: ::: * . .: : . :. .:.:: : : : : .: . : . . : . :* :::* . :.:. .:. :: : * :. :: : :: * : :** . . : ::*.* . :. :* *. **. .: .*: :. . :: : . *: . ..:: : :..***** :*:::. * : . : *. : . : *: : .** : : . :. : : : . . : * .* :* * .: . ... :*: ::* * . .: :: .: . : : : *.**: * .: . : ** : : . :*:. :* : . ::: : .:. :: : : : . :. . * :. * ::* *.:: :**:*.:**:: :* .** :: . . : .:. ** .: :: : : : :: * :* *. :: :::.* : :** .:.*** .:: *.:* .: **: : ::. :. : : * : : ****: * :*::: : . ", "identical_positions": 99, "similar_positions": 324, "identity": "7.69%" }, { "cls_id": "homologset.agr.MGI:2140300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE63-1", "uniprot_id": "D4AE63_RAT", "id": "D4AE63-1", "name": "Alpha-galactosidase MYORG", "aln": "MPQNLQEKSQVYPRHR-LGSHAGPKSLEVIPGATMYTFLPDNFSPAKPKPTKELRPLLCSVVLGLLLVLAAVVAWCYYSASLRKAERLRAELLDLNRGGFSIRNQKGEQVFRLAFRSGALDLDSCSRDGALLGCSRTADGRPLHFFIQTVRPKDTVMCYRVRWEEAAPGRAVEHAMFLGDAAAHWYGGAEMRTQHWPIRLDGQQEPQPFVTSDVYSSDAAFGGILERYWLSSRAAAIKVNDSVPFHLGWNSTERSMRLQARYHHTSYKPPAGRTAAPELSYRVCVGSDVTSIHKYMVRRYFNKPSRVPASEAFRDPIWSTWALYGRSVDQNKVLQFAQQIRQHRFNSSHLEIDDMYTPAYGDFDFDESKFPNATDLFHRLRDAGFRVTLWVHPFVN-YNSSRFGEGVERELFVREPTGRLPALVRWWNG---IGAVLDFTRPEAREWFQGHLRRLRSRYNVASFKFDAGEVSYLPPD--FSTYKPLSDPSVWSRRYTEMALPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIPAVLTVSMLGYPFILPDMIGGNAVPERTAGRPDGPGPERELYVRWLEVAAFMPAMQFSIPPWQYDAEVVAIAHKFAALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFD-KTPVLLTDYPVDLDEVAYFTWAS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZQ1-1", "uniprot_id": "MYORG_MOUSE", "id": "Q69ZQ1-1", "name": "Alpha-galactosidase MYORG", "aln": "MSQNLQETSQAYPRHR-PGSHAGPKSLKVTPRATMYTFLPDNFSPAKPKPTKELRPLLCSAVLGLLLVLAAVVAWCYYSASLRKAERLRAELLDLNRGGFSIRNQKGEQVFRLAFRSGALDLDSCSRDGALLGCSRAADGRPLHFFIQTVRPKDTVMCYRVRWEEAVPGRAVEHAMFLGDAAAHWYGGAEMRTQHWPIRLDGQQEPQPFVTSDVYSSDAAFGGILERYWLSSRAAAIKVNDSVPFHLGWNSTERSMRLQARYHDTSYKPPAGRTAAPELSYRVCVGSDVTSIHKYMVRRYFNKPSRVPASEAFRDPIWSTWALHGRAVDQNKVLQFAQQIRQHRFNSSHLEIDDMYTPAYGDFNFDEGKFPNASDMFRRLRDAGFRVTLWVHPFVN-YNSSSFGEGVERELFVREPTGRLPALVRWWNG---IGAVLDFTHPEAREWFQGHLRRLRLRYNVTSFKFDAGEVSYLPRD--FSTYRPLSDPSVWSRRYTEMAEPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIPAVLTVSMLGYPFILPDMIGGNAVPERTAGRQDGPGPERELYVRWLEVAAFMPAMQFSIPPWQYDAEVVAIAHKFAALRASLVAPLLLELAGEITDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFD-KTPVLLTDYPVDLDEVAYFTWAS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NSJ0-1", "uniprot_id": "MYORG_HUMAN", "id": "Q6NSJ0-1", "name": "Alpha-galactosidase MYORG", "aln": "MLQNPQEKSQAYPRRRRPGCYAYRQNPEAIAAAAMYTFLPDNFSPAKPKPSKDLKPLLGSAVLGLLLVLAAVVAWCYYSVSLRKAERLRAELLDLKAGGFSIRNQKGEQVFRLAFRSGALDLDSCSRDGALLGCSLTADGLPLHFFIQTVRPKDTVMCYRVRWEEAAPGRAVEHAMFLGDAAAHWYGGAEMRTQHWPIRLDGQQEPQPFVTSDVYSSDAAFGGILERYWLSSRAAAIKVNDSVPFHLGWNSTERSLRLQARYHDTPYKPPAGRAAAPELSYRVCVGSDVTSIHKYMVRRYFNKPSRVPAPEAFRDPIWSTWALYGRAVDQDKVLRFAQQIRLHHFNSSHLEIDDMYTPAYGDFDFDEVKFPNASDMFRRLRDAGFRVTLWVHPFVN-YNSSRFGEGVERELFVREPTGRLPALVRWWNG---IGAVLDFTHPKARDWFQGHLRRLRSRYSVASFKFDAGEVSYLPRD--FSTYRPLPDPSVWSRRYTEMALPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIPAVLTVSMLGYPFILPDMVGGNAVPQRTAG---GDVPERELYIRWLEVAAFMPAMQFSIPPWRYDAEVVAIAQKFAALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFD-KTPVLLTDYPVDLDEIAYFTWAS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1U0-1", "uniprot_id": "E7F1U0_DANRE", "id": "E7F1U0-1", "name": "", "aln": "-------------------------MYQVVPGGAGGTITDG--MPIK-KMDKDSRPLVGAGVIGVVLVIAAVTAWCYYIASLRKADLLKTELLDLNKDGFLIRNQAGGIVLKMGFRSGTLDLDSCSKEGVILRCSRSYAG-KVNFFIMTVKPKETVMCYRVRWEELESDRPVEHAMSYN--ESHWYGGAETAVQHWPIAISGQQAPKPFVTSDVYSNRHDFGGILERYWISSNATAIKINDSVPFHLGWNDTEKTMYFQARYQDSPYKPASGRPPYAELSYRVCVGSDVTSIHKVMVRRYFTKPNKVPAKEMFRHPIWSTWALHKTNINQEQLLTYAENIRKHGFNCSHLELDDRYTSQYGDFDLDTRKFPNASAMFQKLKADGILVSLWTHPFVN-YDSANFGHCVQKGLFVMEPTGQLPALVKWWNG---IGGIVDFTNPEARTWFLLQLRTLRNRYGVSSFKFDAGETNYLPWQ--FRTKVHLPDPSTFTRRYTEMAIPFNERAELRSGYGSQNISCFFRLNDRDSVWGHELGLKSLIPTVLTISILGYQFILPDMIGGNAYPNRTDG--NGRLPDRELYIRWLELAAFMPSMQFSIPPWEYDDEVVAIAQRFTELHETLVAPRVIELAGEVLDTGDPIIRPLWWIATSDETAFRVDSQFLIGDDLMVAPVLEPGKQERDIYLPAGRWKSYKGERFDNKEPQLITDYPVDLDEIAYFEWVQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBR6-1", "uniprot_id": "Q9VBR6_DROME", "id": "Q9VBR6-1", "name": "", "aln": "-----------------------------------------------MRFILLSLLLASFCLWEAVHTCASIEQRYKFPNSNVYVRLRRGDKLQYE----LMKGEKSLQTVTFDNFDSSANLVETSSGSYQLTDGQSTVEFTLVKSGVVAGTGSEITHVKVSRDQVLQGTQPRDCVPLKTGSTHWFSGPEQKQHYWPVERQRHSN------YSYLPKELDNFGVGERYWLNGDGVFLYVESNTPLFIDQNS--AAYPDQLCLSAISALPYDPRVTSAKFVYHVAVAKDAKAAHRYAVKTFLGQPTGYPDERMVMHPVWSTWALYKAEVSDDVVRDFAKQILDNGFNNSQLEIDDDWEDCYGAMTFRKNKFPDSKTLTDDLKALGFRVTLWIHPFINNNCTAIYDEAKSKGYLVLDHEG--SSDTQWWNSKPKDAAILDFTKTEVQEWFSKRLKRLQDEDGIDSFKFDAGETSWLPSDPVLQASSSMVTPLQAVGDYVRTVAAFGDMVEVRSAQNTQDQPIFVRIVDKDSEWGWNNGLLTLISSMLQMNLNGYPFVLPDMIGGNGYYE--------KPPTKELFLRWLQANVFMPALQFSFVPWNFDDEAIAISKNFTALHATYTP-YIMKLFKRAVDSGEPVNVPLWWIAPTDEVAQSIYDEFLLGEDIIAAPVVVEGATKRDIYLPEGEWQDGNSDQVY-TGPTWVMDYAAPLDTLPYFLRVGFTLE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : . *:: : * . : : *: : ::.: . .. : ..: :* . * . * . : : .. . . : :* :: . ...: :**:.*.* ::**: . :. . .. *: ****:.. .. : ::...*:.:. *. : * . * * . .:: *:*.*..*..: *: *: :: :*. * . . .*:******: :.:: : :*::* : ** *:**:** : ** : : ***::. : *: *: *:** ***:* :: :.. .: :* : * .: .:***. ..::***..:.: ** :*: *: . .: ********..:** : : : : * *.. . .* . .*:* . :*: . *.*: *:** ** : ** :**.::* :.: ** *:****:***. : * :**::***: .***::***: **.:* *.:**::.*: *: : .. :::* . *:*:*: ******. **.* : .:**:*: ::.***: * :**:*** *.*:. :.: . . * : **.. ** :.** . ", "identical_positions": 166, "similar_positions": 234, "identity": "22.8%" }, { "cls_id": "homologset.agr.MGI:2140313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ALV5-1", "uniprot_id": "SHOC1_MOUSE", "id": "A2ALV5-1", "name": "Protein shortage in chiasmata 1 ortholog", "aln": "MALNGRTMFPAFKYYAIDYLQEDIIKERLYRDALLLQIPSCLNQDKNIIDDKYRTPWTRAIPVQEMEDNSVLEQWRTRFCVEGVPEKKTVT--GVMINGTFEEIVPSSNPNSPPGIENDKLFPSKDYVDDFIPVKCSLYYPGVKAEHQGLLIDEEMIFMNKAMDNHLPTVNGLLSRLKLYLVKDPFLDFKEELSGKDNFT-EYFSVQECSEPFVR-DFHMAEETFCKKKLP--------SVFPSGFKSLISTNPKQEILILPPSKLKKPLNSIPKIMDSVDESE-CFKGDITSKHEFD-TEDIKCNSTENLTFASLCEP-ECSEPGDLEMPPTHLILPRQHSAVSSLHMGFQTFPFSATCKINLLSAGESANKYCMLWQLGGCRNSWVSFLLTVPRFQEPSSQYSLADMRNIFSVKGDSLVINPAKAKGWRQARLHPIMAETLAHLKAYLCHNGLSSQETKLEIFLPTKVFQLESWLELKSRPLPIVPISEKSTDVHQLHPQKRPIPSSEKEVPHLCLSGES-ISVKKSKVEANPKNDQEPEARIMQKPENS-CVGLGCSSQVPSAESASSSQIQAS---YDKKQD-DLDLLSEFIILRSKHQTFPSEADVDVKSHDHDQNNEFQDKEKYSLTLQEESLVASNSKAPEERCEER-TDGVIEIPASDTQCQAYCLLEATANPILKELVCLCTYPAANWKFATVNFDQTRFFLKEQEKKINDATHPDKNDDRKMTFRHAALLHLLITIRDVLLTCNLDTALGYLSNAKDIYKSVLDSRLDNIWRQLKILQFIKEKRPKSNYKIQELQCQILSRLQNQQQMKVLIIIRMDSDGEKHLLIKTLKKIEGLTMTVLRSNDRKKILETTSILKGTNACVVVHNHSIGADFPWSSFSLVVEYNHVGHSCWAEHCQLLDIPFLAFKVAVPDTALQRDALLDGFGGFLLKIPIPYVFFASEGLLNTPEILRLLESNYNITLVERCCCGSLKLFGSTECYVVVTVDEHTAIVVQDLEELHHEKASDNIIMRLMALSFQYSCCWIILYSKETLNSQYHLTEETLRHLAQVYAALVSSGLKSEELDVKLIIAPGVEETALIIRQIADHNLMTSTRDPHEWLDKSWVEVSPSKEEMSLLDFPCINPLVAQLMLHRAPSLHWLLIATPAELQELLPQVPGKVLKHFCSITSLFKISSPSMTKSSQISSLQEDMNQTDLFISQSSAP----IIQEQEEYYPYE----------DSEG-TSSSPVELRA--TPCMLPSAAPHSQRG---CWEDPSCGPDPVQNNPSLMNAESKKVTWPSVPSWSDSESDVFSLARTQVSCEPIMTLTDSQRRGTNG--FVNCP-----EAKGPRNMQVSTPVFLPENSQSHLHWDFKKNSCRKQIYSFNPSCGTEQTTYNKWYSWKDDFSSNQPECLWDEMEDVTYRNANAGTRETFWRELPAVPSWDSPCASDSNANQRGFKGLDFCQRAGNYLGQRSLPVSSSNWGDYKTPTDLMYSQVPQPKKRRLMYEKVPGRVDGQTRLKFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JZW6-1", "uniprot_id": "A0A0G2JZW6_RAT", "id": "A0A0G2JZW6-1", "name": "", "aln": "MALNGRAMFSAFKYYAIDYLYENTVKERLYRDALLLQIPSCLNQDRKIIDDKYRSPWTRAIPVLEITDNSILDEWRARFCVEDVLEKKTVT--GRMINGTFEEIVPSSNPNSPSGVEDDKSEPWKGYVEDFTPVKCSPAYPGVKVEHQGLLIDEEMIFMNKAMDNHLPTVNTLLSRLKLYLVKDPLLEFKEGPCGKDNFM-ECFSVQEHSESFVR-DFRMAEETFCKEKLP--------SVFPFELKSLMSTNSKQEILVLPPSKLKELLDSIPKTVDSVDENE-HFNRDLSSKHGFD-TEDISCSSTENLTCARLCEP-ECDEPGELEMPPSHLSLPRQHSSVNSLYAGFQTFPFSAACKINLLGAGESANTYCMLWQLGSCRNSWVSFLLTVPRFQETSSQYSLADMRNIFSVKGDSLVIHPAKTKGWRQARLNPVMAETLEHLQAYLCHNGLSAQETKLEIFLPTKVLELESWLEPKNSPSLLLPISEKSADAHQLHPQKR--PSSEREGPRLRLSAEQRASVKNSNMEANPKSGQEPAARMMQKTDNG-CVGLGN--PVPSVESASSSQIKTS---YDKNRD-DLDLLSEFIILRSKHQTFLSEAEVKSQ----DQNNEFQDKEKYSLTLQEESPVVSNNKAPEERCQER-ADDVIRIPASDTQCQAYCLLEATAIPILQKLVCLCAYPAANWKFATVNFDQTRFFLKEQEKIINDAIHQDKNDDRKMTFKHAALLHLLVTIRDVLLTCGLDEALGYLSNAKDIYKSVLDSYLDNIWRQLKILQFIKEKRPKTNYKVQELQCQILSRLQSQQKMKVLIIIRMNSDGEKHLLIKTLKKIEGLTVTVLRSIARKDFLETTGVLKGTHSCVVVHNYSIREDFPWSSFSLVVEYNHVGHSCWAQHCQQLDIPFLAFKVAVPDTALQTDALLDGFGGFLLKIPIPYVFFASEGLLNTPGILRLLESNYNITLVERCCCESLKLFGSTERYVVLTVDEQTAVVVQDLEELHYEKASDNIIMRLMALSFQYSCCWIILYSKETLNSQYHLTEKALHHLAQIYAALVSSGLKSEELDVKVIIAPGVEETALIIRQIADHNLMMSKRDPHEWLDKSWVEVSPSKEEMNLLDFPCINPLVAQLMLHGAPSLHWLLRAAPAELQELLPQVPGKVLKHFCSITSLFKISSPSMTTSCQISSLQEDMNQTDLFISQRSAP----IIQDHYSYDISE----------ETVRRDTSSPRELRERLPPCLLPAAAPHSQRSRCSGWEGSGCGPNPVQRNPFLMNTESKKITRPALPSPRHSQSDVFSLGLTQVSCEPKMPQTDSQRRGSQD--FVNCP-----ETKGPRNVQVSNLVFLPEGSQPHLHWDFKKNSCRKQSSSFPPSCGAEQSTYSKRYSQKDDFSRDPPGRAWDELQDVTCRNANAGTKETFWREP--VPSWDSFCATDSNVNQRGFKGLNFCQRAGNYLRQRRLPGSSSNWGDYETPTDLMYSQAPQPKKRRLMYEKVPGRVDGQTRLRFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VXU9-1", "uniprot_id": "SHOC1_HUMAN", "id": "Q5VXU9-1", "name": "Protein shortage in chiasmata 1 ortholog", "aln": "-----------------------------------------------------------------MTDTSVLDQWKASFFVEDFLEKKTITRMVTQINCEFEEVVPSSNPDSQIEVEEVSLYTHMDYNEVFTPVSCLEKCSALQNQNQDLFIDDKGILFVSSRK-HLPTLPTLLSRLKLFLVKDPLLDFKGQIFTEANFSRECFSLQETLEAFVKEDFCMDKVNFCQEKLEDTICLNEPSSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEIINYVDEKEKLFERDLTNKHGIEDIGDIKFSSTEILTIQSQSEPEECSKPGELEMPLTPLFLTCQHSSVNSLRTELQTFPLSPVCKINLLTAEESANEYYMMWQLERCRSPLNPFLLTVPRIQEPHSQYSVTDLKKIFSVKEESLVINLEKAEWWKQAGLNLKMMETLEHLNTYLCHDNLSSNDTKIEIFLPTKVLQLESCLEHKSHSSPIALIDEKSTNAHLSLPQKS--PSLAKEVPDLCFSDDY-FSDKGAAKEEKPKNDQEPVNRIIQKKENNDHFELDC--TGPSIKSPSSSIIKKASFEHGKKQENDLDLLSDFIMLRNKYKTCTSKTEVTNS-------DEKHDKEACSLTLQEESPIVHINKTLEEINQERGTDSVIEIQASDSQCQAFCLLEAAASPILKNLVSLCTLPTANWKFATVIFDQTRFLLKEQEKVVSDAVRQGTIDEREMTFKHAALLHLLVTIRDVLLTCSLDTALGYLSKAKDIYNSILGPYLGDIWRQLEIVQFIRGKKPETNYKIQELQCQILSWMQSQQQIKVLIIIRMDSDGEKHFLIKILNKIEGLTLTVLHSNERKDFLESEGVLRGTSSCVVVHNQYIGADFPWSNFSFVVEYNYVEDSCWTKHCKELNIPYMAFKVILPDTVLERSTLLDRFGGFLLEIQIPYVFFASEGLLNTPDILQLLESNYNISLVERGCSESLKLFGSSECYVVVTIDEHTAIILQDLEELNYEKASDNIIMRLMALSLQYRYCWIILYTKETLNSEYLLTEKTLHHLALIYAALVSFGLNSEELDVKLIIAPGVEATALIIRQIADHSLMTSKRDPHEWLDKSWLKVSPSEEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPEVPEKVLKHFCSITSLFKIGSSSITKSPQISSPQENRNQISTLSSQSSASDLDSVIQEHNEYYQYLGLGETVQEDKTTILNDNSSIMELKE--ISSFLPPVTSYNQTS---YWKDSSCKSNIGQNTPFLINIESRRPAYNSFLNHSDSESDVFSLGLTQMNCETIKSPTDTQKRVSVVPRFINSQKRRTHEAKGFINKDVSDPIFSLEGTQSPLHWNFKKNIWEQENHPFNLQYGAQQTACNKLYSQKGNLFTDQQKCLSDESEGLTCESSKD---ETFWRELPSVPSLDLFRASDSNANQKEFNSLYFYQRAGKSLGQKRHHESSFNSGDKESLTGFMCSQLPQFKKRRLAYEKVPGRVDGQTRLRFF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.*:*::*:: * **.. ****:* ** ***:******:* :*: . . .* : * **.* ..:: ::*.*:**:: *:: .: . ****: *******:*****:*:** : ** * **:** *.**: ** * : .**::** * * : *:... * ** : . *:**: *:.:*: :: ***.* *: *::.** :: **. .*** ** .** **.:**:**** : * *. ***:*.** :****:*..****** * **** * *:*** **.. .*******:**. ****::*:::***** :****: *:: *:** *: * *** **::****:.**:::**:********::*** ** *. . : *.***::.* *** ** :* * * :* : * * : * :**..*** *::** :*. . *. ** :*.*** *: : :.*::: ******:**:**.*::* *:::* . :* :*** ******** :. .*: ** :** :*.**.* ***:****:*****:* ***::**.**: *:******** ******:****** :.** : .. *:*:***:********:*********.** ******:*****:*:*.. *.:*****:*:***: *:*::***:********* :*.**::********:******:*** *:******:***:* **.:**: .:*:** :****** * *****.**:*****:* .***::**: *:**::**** :***.*: .:*** ******:* *************** **:********:**** *. *******:* ***:*:**:**:::******::***************:** ******:******:* ***::*:*** :****** **:*******:******* ***********.** *.***********::****:*** ****************: .*****:* *: .:******:** ***************.*.*:*.* **** **: ** . : ** **. :**:: .* : .** **: ..:**..:.:.* . *:...* .: *..* *:* **:: : :. . .*:******. **:.**. . **:*:* : *:*. *:** * :** :* *.:*. ***:**** .:: .* . *::*:: .* ** *.:: : ** :.:* ..:: ****** *** * *:***.**: *:.* * ****: * *: ** * ** :: *.:* ** ** ***** **************:*:", "identical_positions": 774, "similar_positions": 348, "identity": "50.59%" }, { "cls_id": "homologset.agr.MGI:2140321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDG7-1", "uniprot_id": "PAFA2_MOUSE", "id": "Q8VDG7-1", "name": "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "aln": "MGAGQSVCFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCQ-ASEKCEQPLWIPRYEYSMGLADYLQYNKRWVGLLFNVGIGSCRLPVSWNGPFKAKESGYPLIILSHGLGGFRASYSAFCMELASRGFVVAAVEHRDQSAAATYFCKPTSQESSPA-ESLEEEWLPFRRIKEGEKEFHVRNPQVHQRVKECVRVLRILQDASAGKTVVNVFPGGLDLMTLKGSIDRNRVAVMGHSFGGATAVLALTQEVQFRCAIALDAWMFPLERDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAFVTGNLIAKFFSSNSRGTLDPYESQEVMVRAILAFLQKHLDLKEDYDQWSSFIEGVGPSLIQGAPHYLSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83006-1", "uniprot_id": "PAFA2_RAT", "id": "P83006-1", "name": "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "aln": "MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCE-ASETCEQPLWIPRYEYCVGLADYLQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGFVVAAIEHRDQSAAATYFCKQTSQESSPT-ESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVRVLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIALDAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAFVTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAPHYLSSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99487-1", "uniprot_id": "PAFA2_HUMAN", "id": "Q99487-1", "name": "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "aln": "MGVNQSVGFPPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCTGLAEYLQFNKRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAFCMELASRGFVVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHVRNPQVHQRVSECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGATAILALAKETQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQHEQSRIITVLGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKHLDLKEDYNQWNNLIEGIGPSLTPGAPHHLSSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..**: ***::*** :** *****:.*:**:*******: *.*. ***********. ***:***:*** *****:.:**************:*:*******:*****.**. ****************. ****:***:***** :.:*..*: ***:***:****::****************..**:***:***:.:**:.*.*::***********.** .**************:***::*.*****:**********:**************.*****:******************:****:**************:*.*:**: :**:*****.*******:**************:**..:***:**** ****:****", "identical_positions": 301, "similar_positions": 75, "identity": "76.79%" }, { "cls_id": "homologset.agr.MGI:2140327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PEI3-1", "uniprot_id": "PHR4B_DANRE", "id": "Q6PEI3-1", "name": "Phosphatase and actin regulator 4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEN----------------------------------------RDDEVE-----------------HQHSTMGSEGGTAGDGTPPPKRKGKFSTLGKIFKPWKWRKKKSSEKFKETSE--VLERKMSMRRPRQELIEQGVLKELPDNESGEAHGHKAPYVKNGH-----TLPVGVGGSLALEQVHSPSESEFRINPVWLPQPEDRRARAPSDGDHRGALGPRASNQDDGRRGGWSVGTEDWKNNLAWHGEDIRRGGRAHAEMDKRPGLMKAPSEDGRRTRPEPDWKPTLPRHSSVEEGRGRRE-----SDSSQYLPNSEMMRDTLREPLPPKQSIMPPKWLMTSTPEPGSDSLPRTPVHN--PAAPSFCSSNSSSSSSAGKPLRNVSSAGANTAPPGG-------------APLTTSSAPCSMGTIPNHPSKQPPMPPPKPINRSNNPAIM-AELTQGGMN--LVPAKPSPPMPPKRTTPVTKRNPEDSPLTIASLPSILSEDMRANIP-----GGYQLPPPPPS-PPLPTHIPPSPPRA---------HTHHLLHQHSYPYP---LPQPLPVHFDPPSPPEDPP-----ARDEDD-YSDEEEEE-----EDDEDDEEPPPDHL---PSPQSQPELEPRSRRCLVGELS-VSVIPEGNNSSEEEEDEEDQHPEESDSDGPVLYKDDESDEDEEDDSPPSALASRVKRKDTLALKLSSRPSAPDRQAPERQAKSEHSGLSWQSKEQWEAIRTQIGTALTRRLSQRPTAEELE-QRNILQPKNEADRQAEVREIKRRLTRKLSQRPTVAELQARKILRFHEYVEVTSAQDYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHEESRIYTRFHRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QIC4-1", "uniprot_id": "PHR4A_DANRE", "id": "F1QIC4-1", "name": "Phosphatase and actin regulator 4A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGQGASTQTLNPNL--------------------------AYITDDEVD-----------------HSMP--ESDGANPGAGNPSAKSKGKFPSLGKIFKPWKWRKKKTSDKFKETSEGLVLERKMSVRKPREELIERGLLKDIPENESNDVN-HKAPPVKNGH-----TGPV----------------------------PGDRKSDSGSEIDQDRRMDDTGERKEKRKRIGK-------RNDGTERMTEMIQSFQKMSLMQRSVGVQFVPEPKPASTSTKESQPP--PKQAILPPKRVIAA-----PSSAEPAPVP-----------PPPIAKPPPRTVSLNVDDSSRTILIPSLIAGDREVPPTVPAHTTPATVSTHKTLPTVP---AHMTPPTV-------------PAHVTTPAAPAHSNPPAVLLKQPPMPPPKPVHHSSNTALQGLDLSTVDPSQVPVPVKRSPPIPPKRNTPVTKRNSGDSSANLPEPPPPAPTSVPIPAA-----APISAPPSTQSDPPSPTTEPPSQPPP---------LPLHIRIQRALNSPGPVHPNPEGSQRAHSLLFETPPDLINEALGGGR-YSLPVTIEPLRLPEDDDFDMEEELQKLRAGPRPTQKPELEPRSRRGLVEDPQ-VAVIPEDAGSESSEEEED-----ESDSDQSIKYRDDNEEDDDEEDVPKSGLASRVKRKDTLALKLE-------RQQEKEKSQEEDS-STWNNKEQWEAVRNKIGTALTRRLSQRPTAQELE-QRNILLAKNEEVRRAERSEIKRRLTRKLSQRPTIADLQARKILRFHEYVESTHAQDYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHEESRIFTRFHRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q501J7-1", "uniprot_id": "PHAR4_MOUSE", "id": "Q501J7-1", "name": "Phosphatase and actin regulator 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDPS--------------------------------------EEAEQP-----------------SGDPGMGMDSVEAGDTTPPTKRKSKFSALGKIFKPWKWRKKKSSDKFKETSEV--LERKISMRKPREELVKRGVLLEDPEQDGEDSGKLSHAALKNGH-----TTPIG-------------------------SARSSSPVLVEEEPE--RSLRNLTPEEESKKRLGS---TGSQPNSEAEPGPEHAPK-QPLLPPKRPLSSS-----CEAKEVP-AGSTARSVSSTSGSTTVTSAA-----TTAATDMTKTV-KSFVGPTPAPAPAPRTLP-AAPASANTAAT----TTAPAKQPPIPPPKPAQRNSNPIIAELSQAMNSGTVLSKPSPPL-------------PPKRGIPSTSIPSLEPAASFTTKTANDQREK-TVSLCLEPPLIIPPSSPS--PPLPTHIPPEPP-RSPLVPAKTFQIVPEVEFSSSSDLFQDISQQED-----QKTEVPKKIQDQSFGESHIP-SRLPP---------LPLHIRIQQALTSPLPVTPPLEGTHRAHSLLFENSDSFSEDTGTLGRTRSLPITIEMLKVPDDEEEE--------------QTCP---------FVEDVTSTSATPSLPLCLREEE-KES----DSDSEGPIKYR-DEEEDDDDDESHQSALANRVKRKDTLAMKLS--------SRPSEPETNLNS-WPRKSKEEWNEIRHQIGNTLIRRLSQRPTAEELE-QRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAHDYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHVDSKHFTRYHRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AQY6-1", "uniprot_id": "A0A8I6AQY6_RAT", "id": "A0A8I6AQY6-1", "name": "Phosphatase and actin regulator 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAIPPLSTLANSGMEDPFDTAPPTPTCWLYSGMTPVSESTKRKALFWCHHSTRHMIEEAERP-----------------SGDPGLVMDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSE-----------------------------GGEDSGKLSHAALKNGH-----TTPIG-------------------------SVRSSSPILSEEEAE--GSLRNLTPEEDPKKRLGS---TGSQPSSEAEPGPEQASK-QPLLPPKRPLSSSDEGNEGQAKEVP-AGSAARPVSSTSGSGIETPAA-----TTAATDMTKTLTKSFVASTPAPTPAPRTLP-AAPASTNTTAT----HPAPAKQPPIPPPKPAQRNSNPIIAELSQAMNSGTLLSKPSPPL-------------PPKRGIPSTSVSSSEPAASATAKTANDQREK-TVSLCLEPPLTIPPSSPS--PPLPTHIPPEPP-RSPLVPAKTFQMVPEVEFSPSLDRFQDISQQED-----QKKEVPKKIQDQSFGESHIP-SRLPP---------VPLHIRIQQALTSPLPVTPPLEGTHRAHSLLFESSDSFSEDTGTLGRTRSLPITIEMLKVPDDDEEE--------------QICP---------FVEDMTSTSATPKLPPCLQEEE-KES----DSDSEGPIQYR-DEEEDDDDDESYQSALANRVKRKDTLAMKLS--------SRPSEPETSLSS-WPCKSKEEWNEIRHQIGNTLIRRLSQRPTAEELE-QRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHVDSKHFTRYHRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZ21-1", "uniprot_id": "PHAR4_HUMAN", "id": "Q8IZ21-1", "name": "Phosphatase and actin regulator 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDPF--------------------------------------EEADQP-----------------TTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEV--LERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGH-----TTPIG-------------------------NARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGS---TGSQPNSEAESVPENVPK-PPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTS--ITTAPAA-----TTAATSLAKTVNLSVT-----PSPAPRTLP-AAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPL-------------PPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPS--PPLPTHIPPEPP-RTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQED-----QKKEVPKRILDQNFGEPHIP-SRLPP---------LPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE-------------QTCPST-------FSEEMTPTSVIPKLPQCLREEEEKES----DSDSEGPIQYR-DEE---DEDESYQSALANKVKRKDTLAMKLN--------HRPSEPELNLNS-WPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELE-QRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZN0-1", "uniprot_id": "Q9VZN0_DROME", "id": "Q9VZN0-1", "name": "Phosphatase and actin regulator 4", "aln": "MSLRSNKLHSQQSTASSNSNGSNSSGNSGSNSNVQQQHPPMAYQQQQQQLLQQLQQQQKFQAQQRGNTSRNNLATLVAAINGHDGGQNSPGNSGYQLSPAAASRVAHAPPHSPLGPPSYSAATAQSAFSYYGQHQQHQMQLNHNYQQQQQQQFQLQQQQQQLQLPPPDLTDGIDHPSAQAATPPDSPNAQSTGPSDLEQQLCVVAKMQKSVTITVTPQRSNSMDFLNFEEKRQLIASSLSLSDILHSSNAQQQQQQAAKDGLAINGGQCAKKQNGAAIRTNSLGSGTRTPPLERKSKLSALGRFFKPWKWRRKKKSEKFEAASKS--LERKISVRANRDELVQKGILMPESPLGNIPEPGEESYYNNSNSGATAN------------------------------GSLLNSAVHNNSMSQANNSINATTGNPLISAAQQQLN--QGLPNSISVQQFNGQNQNPQNSMANGLVGGGGGGGDGSSDTSSLSGGVPHSQSAPQQLGVGQPPPPLTPLAQHHQALAQQLQQRFAISNNNEPRKDKTDAQQQQHGGNGTISTPNIEQPTCQGSMLPPPGGGGHHQVDGSGKMERPNTLAGANKLTRRGVNICYHNEHMYGEDGKMVGGPPGSTPPPYPGGKLPPGVMLSELPEPPIPLSEIGPIPPPPMFSTPSPTLIAGRPHGPGAVNDQDYQQDYDYDDNDPDQDELDSDDEYAPYGGNHVRMMDTQRVEEIPAKEPKPNAVPLKSALK---------KKGGMQPASASTPVTPTQEHGAGSAATAAAMANSNGGIGSMAAAAAAAAQQSANQRPLVVRQDAAGNN--------YSLKPILRPRIRLCRQQMFNIQLPCTVENKENARPFVIRESSSD----SDDSDGHIVYR---------DEDNDNTRLAKLARKESLSLKLQ--------LRPDKQDLINRNILHQVNDNELKESKEAIGARLIRRLSMRPTAEELV-ERNILKTQSPAEEKKQKEEKKSYLLRKLSFRPTVEELKEKKIIRFNDYIEVTQAHDYDRRADKP-WTRLTPKDKAAIRKELNEFKSSEMAVHEGSRHLTRFHRP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53858-1", "uniprot_id": "BNI4_YEAST", "id": "P53858-1", "name": "Protein BNI4", "aln": "-------------------------------------------------------------------------------------------------MSDSISDSKSSELLNSTFYSSTSINTLDHARTFRNSLILKEISDQSLNSSIKPCESVLDRDVESSVLQRSFGESNARDSEVQTVNMTTSPSLSALADILNERSKYADQKTRKAQNIESSIIEE----------------------------EEEAEEQNNSIN-------YHEDITGSRLSVREEANENLAMTSPNLIDIDGSNSIQVAPLSLPSFEEPDFLSTPRVKPDSQGPRSKVSTRRTILERDNNLPVKREENTIINSETESTTHSAP-----------------------------------FLKEDPKPSPPSSKLYNPKVRLNKAEARKYTDSSAQRTTSAGSVLEDTSMHKKKKSIFSFLKKKEPKPVIGNNSVTNEKNKMSSSSTFSMNIQTSLKTPEKLKKK----SHSSSSIFNSFLKGKIETSDSPRKEPMRQKKRTPKSKDKKQDTEQIIDAASVLSTESPLLRKNHDDTPVKIDHVTRSIDQRKPTPLNMDLILG----------GDKQINTPLQEHVREDDDAKNDLQLPTKDNFLSLDYEAPSPAFSKHDTGEVLFPKFLDNHEVDSIVSLERTRSTKSNKRSSMNSQRRSLTDTLSIKAQSE--GMFITEASSVVLSTPDLTKSPASSILKNGRFEYSDNFSREHSYEGTTNEDFLDIKDDSGPLKKDDIFLESIEQKFDQLVMASDEEKTEVERDVPKPREEPLKKDSERQSVFADDDNELISDIMEFASFINFGDDDLNLDLDLGDTTASYATETPEPVGNDEVNRSGTFDTRNNKEDSYKERETQSYSAAGATTYGDERQGQLHTFE----QDGSEINDNEFENEDFNKHIEQPIEVTPRNNAYLPEFEPNRPVSMSFKGLKAPRMNTSFIDSMTPDSPVKSDLTSLGEVYVNSNNDQGVRFSSQIILYDTYGEFEYDRHPEISTCNQLTPQLAQMIKLELNELKS-AMEVHDDSRCYTHFY--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . .. : . . . * . : .: :. . . :. . . : . . . . . . . .* .. . * . : : . :: . : : * . . : . . : : : :* . . :: . * . . **.. .: : . * * . . : :: : :***:.: . .:*** *: ****:** * ** *: *::: ", "identical_positions": 28, "similar_positions": 85, "identity": "2.59%" }, { "cls_id": "homologset.agr.MGI:2140340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VW7-1", "uniprot_id": "AKNA_MOUSE", "id": "Q80VW7-1", "name": "Microtubule organization protein AKNA", "aln": "MASSGAKAQWVGPSLGQGPRRRRWAWAEEQ-DTDGRRDQGWGNSQSLPEAPSPELLEDFRRAQEHLPPLEWDPDMQ-------DSEESSGEETEADDASSPEGSTVPLPWLSRSNQQLDMSEEELDEASGRPEVDLAGESCTELECED------QGDSSPPPPGQGPAKGWVTFIKQGSNYRPSEHLEAQPSVEHSRTKSWSSGTVSLRQPSDSLGSTWEGDTEVPQPSILPKALPQSPCHNFPHPGDRNGGDVAPATPTEFRDSLAAPAQNAECSAGTWGEETTSLPSSRPEDQTWKRTKTSPKPLPSRFTGSVSPLSTRLGAIKKVVPQHKQGATLAGHSSSQAPKYGRGRRLNYPLPDFSKVGPRVRFPKDENYRPPKSRGHNRQ-QGSTRPLIFKSPAEIVRDVLLSSGEASLAKESSLAHTITRVPQEFQTPEQATELVHQLQEDYHKLLTKYAEAENTIDQLRLGAKVHLYSDPPQPSQSFCSGSMPQGSKVLSFSIPQPRVAEWWPDPAQDPQASEATGWPFPRTDLSPSSSPGVATPGRLPQSQGIATDQPSTGQTQALTSQASRLLAKVQSFEELVLAGHLPPQDQIKSLEQLRAAHMALEAEYLQACREELLDPQLDASQGSPRTLNLCRELEAEIYHLGQRLEELQDHMDQTQRETEPCRPD-LQDSTPTMSFLPQSAHLSMPSGPVSLPDGQT-YQEPATTTTTSPGSSCTLPINKKLSLS-IKTEESPRGLPVPLRDRTLQVEQDFHGLLERYLSVKSLPEALRDEDEDDLEEEEEEQDHQGPLEVDSPATAPGKTEAVRVPPGERPTQAEESHRDATQEDEEQMGPMKSPDFRPSMARDTYTPVLDTAEVAQRG---------TKAMVSHQSSLTSLEESRPSELLPRKALLRAGGPHTEEPWMVSPETDSGFVGSETSIVSPFTQTPEHRLSHVSTSGPSAQHLTASVPGDRTSHPKARGLMVPRRATETGIPRSRTQQHFSSLS-SPGRGAQSCHLEETSVAKIAVPRSEFKRQKQISKQLLPSGRTSPDSAPAPTAASTPHGSAESTANLLLNRTERDQAIKDLQAEVSRLRLQLEDSLHRPHPDGPACVASAFNHSTQTQEKLG-SSPSWGPHYGSKSTERLSREPNGVEPAEPMGRRRARSSSVPRDVPRLYLSSESESPAPRLSSEKSRTFEEHPEAAQWGTRPQSSSKRRERVSFRGQYTGQEYHILSPKAILKDSGTPSCPHCHPIRTQDTGSAVSRDTTRGSSAADTLRCALCGEVKSSAEADGSSSGPS--EKNTPKK--PSTPILKRKNRQTGSPVRMAPGLWYLAAAPPAPAPPALAYISSAPIMPYLPPTVYYAAPAPTSAQTASPQPARGP----RRTRHSVQLGLNDLEELQAALREAAQAAENVRSTTRQLSRSLSADLRHARSLRGSCLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLV5-1", "uniprot_id": "D3ZLV5_RAT", "id": "D3ZLV5-1", "name": "", "aln": "MASSGTKAQWAGSNLGQGPRRRRWAWAEEQ-DADGRGDQGWRNKQSLPEAITPELLEDFRQAQEHLPPLEWDPDMQ-------GSEESSAEDTEADDVSSPEGSPVPLPWLSRHSQRLGLSDEELDETPGSPEVDLAGESSTELECED------QGDLSPPVAGQEPARGWVASIKQGSNYRPSEHPEAQPSVEHSRTKSWSNATMGLGQPSDSLGSTWEGDTDVPQPDTLPEALPQSPCHNLLHPDDRNEGDVAPATPTEFRHSLAAPARNPERSAGTWGRETTSLPSSRPEDQSWKRTKASPKPLPSRFTGSVSPLSTRLGAVNKVVSQHKQGATVAGHSSSRVPKYGRGR-LNYPLPDFSKVGPRVRFPKDENYRPPKSRGHNRQ-QGSTRPLIFKSPAEIVRDVLLSSGDTPLAKESSLAHPVTRVPQEFQTPEQATELVHQLQEDYHKLLTKYAEAENTIDQLRLGAKVHLYSDPPQPSQSFCSGSMPQGSKVLSFSIPQPRSAEWWPDPAQDSQASEATGWPFPRTDLSPSSSPSMATPGRPHQSQGIAVDQPSTGQIQALTSQASRLLAKVESFEELVLAGHLPPQDQIKSLEQLRAAHMALEAEYVQACGEEHLDPQLDASQGSPRTLNLCRELEAEIYQLGQRLEELQDHIDQTRAEPEPCGTD-LQDSTPTIPFQPQPAHLPMPSGPVPPPDVQT-YQEPVTTTTS-PGNSCMLPMPKEVNLG-IRTEGSPRGLLVPLKDRKLQAEQDFHGLLERYLSVKSLPEALRVEDEEDPEEEEEQQDHPDTLKVDGSTAAPGKTEARRASPGQHPAQAEERHRAAIQEDKEQMVSMKSSNFQPSMARNRYTPVLDTAGVAQGG---------TKPMPSHQSSLTSLEESRPSDLLPRKALLRAGGPHTEEPWMVSPETDSGFVGSETSIVSPFTQTPEHQISHISTPGPSAQHLTVSAPGDGTSHPKVKGPVVPRRATEAGIPRSLTQRHHSSLS-SLRRGAQSCHLEETPVAKIAVPRSEFKRQKQISKQHLPSGTTSPDSAPAPTAASMPHGSAESTANLLLTRTERDQAIKDLQAEVSRLRLQLEDSLHRPRPDSPACVAPAFNCSTQTQKKLVDSSPSWGSRYGSKSTERLFGEPSGAEPAEPMGRRQVRSSSVPRDVPRLS-SSESESPAPRLSSEKNRTFEEHPQAAQWGTRPLGSTKRRERVSFWGQYTGQEYHILSPKTNLKDSGTASCPHCQPIRTQDTGNAVSREP-LGSSAADTLRCSLCGGVKPSAEADGPSPAPS--EKNTPQKPAPSTPSLKRKKRQTDSPVRMLPGLWYLAAAPPAPAPPALAYIS-APIMPYPPPTVYYATPAPTSVHTASPQPAQGP----RRTRHSVQLGLNDLEELQAALREAARAAENVRSTTRQLSHSLSADLRHARSLRGSCLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z591-1", "uniprot_id": "AKNA_HUMAN", "id": "Q7Z591-1", "name": "Microtubule organization protein AKNA", "aln": "MASSETEIRWAEPGLGKGPQRRRWAWAEDKRDVDRSSSQSWEEERLFPNATSPELLEDFRLAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASGDKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPSHHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQ-LNYPLPDFSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDTPPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPPQPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTSMPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQRLKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP-LGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGSCLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** :: :*. ..**:**:********:: *.* .*.* :.: :*:* :******** **:*********. * * *:*.*::**:*..** .* **.**.: .::*.:::** * : * **: ****.:.* * :*: ** *: *:***: :*.*. : *** *.:**** * ::***..*:.* :*****.*****:*: *** *.::**:.*.*:: *..*. *.** *** **:.* *.**:..: ::. * .*** : ..:*::: **:**:********* **:***..: . .: . :****:**:***..******: *********************.*******.***: *..:************::******::.***::. **.:*************************:*********************:*:******.:*: :* :***:*****:***** *****.**:*.*** *:*** .* ****** ..:.* * :.:.*: **.*: * ***:****::****:***.*: **:* ****:*.:::*:*** *** **::** *: * .*:*:* :: ********:**. ****::*:***: *.** .* ****::. *.:**. *** .. * :* **.***:: . ..* * : ::. . ..* *:. . *:.: ** ** :***:************:* *:*:: *****::. ..*:**. :::***:** *. * : *.***: * . :* *:* .**...*:.*:**: : . *..* .* * **. *****:**** * *: **:*.* *.**** **.**.************** ***:******::**:**.*. ** ::.*.* * :*:**.:* ::******.. *** :*:: ** * . : * . **.* .*::*** ***: :*:**:* **. ** .****:**. * *.:*: ..:**.*: ***** :** *******:******:* ..*: *.**: .::*: : *..:**.:********* ** * * * **::.*******:* ** ***** *: * ***.:* :: *:**: *.* .*: :**:* *****:***:****: *..** *****:******:*.**: :. *...****:*.*** * ...****.....* ** *.:: .*** *::.:*:.*. * *******:*********:**** .***** *.:****...***.:.*: *. .. ** ***:**.*.*****: ** .*.:***.*******: *******:*:********", "identical_positions": 768, "similar_positions": 394, "identity": "53.3%" }, { "cls_id": "homologset.agr.MGI:2140356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7D7-1", "uniprot_id": "D4A7D7_RAT", "id": "D4A7D7-1", "name": "GDH/6PGL endoplasmic bifunctional protein", "aln": "MKCTGIWKMLVAAVCLALLG---CLQAQEFRGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKALESLSCPKDLVPSRCDELKAQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGVIRDTLQNHLTEILTLVAMELPPNISSSAAVLQHKLQAFQALRGLQKSNAILGQYQAYSGQVRQELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNRAYCTQGERHWVPERSRCLPQQIVFYIGHGELGHPAILVSKNLFKPSLPAQ-SWKGVQDQPGLHLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLSFEVPRLYPGGAENDHLLDFEFSGGQLTFSQQQLEVLMPELGSVPKPSDFQVLRAQYRKSPLITAWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPRGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFX1-1", "uniprot_id": "G6PE_MOUSE", "id": "Q8CFX1-1", "name": "GDH/6PGL endoplasmic bifunctional protein", "aln": "--------MLLAAMCLALLG---CLQAQELKGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKVLESLSCPKDLVPSRCDELKGQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRIFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETIDAEGRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAAVLQHKLWAFQALRGLQKSSAILGQYQAYSGQVRRELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNRAYCTQSERHWVPEQSRCLPQQIIFYIGHGELGHPAILVSRNLFKPSLPTQ-KWKEVQDQPGLRLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLAFEVPRPYPGGAENGQLLDFEFSGGQLTFSQQQLEVLIPDLGSVPKPSDFQVLGARYRQSPLITAWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPTGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95479-1", "uniprot_id": "G6PE_HUMAN", "id": "O95479-1", "name": "GDH/6PGL endoplasmic bifunctional protein", "aln": "-----MWNMLIVAMCLALLG---CLQAQELQGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGRGHSFSFHGAALTAPKQGQELMAKALESLSCPKDMAPSHCAEHKDQFLQLSQYRQLKTAEDYQALNKDIEAQLQHAGLREAGRIFYFSVPPFAYEDIARNINSSCRPGPGAWLRVVLEKPFGHDHFSAQQLATELGTFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIIMKETVDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPHNVSSAEAVLRHKLQVFQALRGLQRGSAVVGQYQSYSEQVRRELQKPDSFHSLTPTFAAVLVHIDNLRWEGVPFILMSGKALDERVGYARILFKNQACCVQSEKHWAAAQSQCLPRQLVFHIGHGDLGSPAVLVSRNLFRPSLPS--SWKEMEGPPGLRLFGSPLSDYYAYSPVRERDAHSVLLSHIFHGRKNFFITTENLLASWNFWTPLLESLAHKAPRLYPGGAENGRLLDFEFSSGRLFFSQQQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAWSEELISKLANDIEATAVRAVRRFGQFHLALSGGSSPVALFQQLATAHYGFPWAHTHLWLVDERCVPLSDPESNFQGLQAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSSFDLVLLGMGADGHTASLFPQSPTGLDGEQLVVLTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKREITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGT2-1", "uniprot_id": "E7FGT2_DANRE", "id": "E7FGT2-1", "name": "", "aln": "-MLRIRWELLLMAIICGQRGSADNHEAKQSLGHVTVVVVGGTGDLARKYLWQGFFQLYADQVGKGHSFSFYGGGLSPAEKGTPVLFGILKELACPPELTAERCALVKEQFLHLSRYHQLKTAEDYEKLCQQIKQQVGQESMTEAGRLFYLSVPAFAYAEIAERINNTCRPPSDAWLRVVLEKPFGHDFASAQLLDKKLSGQLKEEEMYRIDHYLGKQVVSKILPFRKENKKLLDPIWNKHHIERIEIVLKETLDAKGRIQFYDQYGVIRDVLQNHLTEVMTLMLMNLPANLSNSKEILLNKLHFLASLQHIDNSNAVVGQYQAYNGEVQAELNKTKDYFSLTPTFAGVVIHVDNAQYEGIPIFMTSGKALDERVSYARVLFKSDVFCVQD-----PNNVQCKSKQIIFYLGHGNLQYPSILVSKNLLKPEIVSSGDWKEVTEYKEVNLLGLPLSDYYIQSPVAPREAYGELISHVFFGRKDSFISAEGLLASWAFWTPLLESLSHVYPRIYPGGVSNGNLLNFQLRGHQIAFSHEAVVNVIN----RGAEENFQVMQGKYRSSEMISAWAQELVERLASDLLLAAEEAIRREGQFHLALSGGSSPVALLRALALNLYTFPWRNTHIWQVDERCVPHTESGSNFRSIHDLLLQHIRIPYFNIHPMPVHLTQRLCVEEDGGATLYEKEIQKHVNASSFHYILLGVGQDGHTASLFQDTKLESDGERLVTLTESPIKPHQRMSLTFTAINKARRVGVLVMGKSKHELVTQLSRIKGESSRYPITKVQPNNGSLIWYIDYDALLG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *: . * :*:: ***:::::*.*****:******:**** *:.*:******:*..*:..::* :: *:.*:** ::...:* * ***:**:*:****.***: * ::*: *: : .: ****:**:***.*** :**..**.:*** ..******:*******. *** * .:*. ::******:*******.*::*****.:*:* ** :**:**:**:**::***:** ** .**::******.*******::**: *:** *:*.: :* :** : :*: ::...*::****:*. :*: **:*...: *******.*::*:** ::**:*::: *********.*.*::**. . *.*. . . :* .:*::*::***:* *::***:**::*.: : .** : :.*:* ****** ** ::*:. *:**:*. **: **::*.***** ******:**:. ** ****..*..**:*:: . :: **:: :: .:***: .:**.* :::**.:**:.:**.*: :* .*:*: *:***********:**:: ** * *** **:* ******* ::. ***:.:: ****:*:**:********* ****.*** ** * **. * ***. :***:* ******** :: **::**.** ** :**:****::. **:*::*.*****: *:*:.* :**: *..::**: * * .*.*:**:**:*:**", "identical_positions": 392, "similar_positions": 252, "identity": "48.94%" }, { "cls_id": "homologset.agr.MGI:2140359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AB80-1", "uniprot_id": "A0A8I6AB80_RAT", "id": "A0A8I6AB80-1", "name": "", "aln": "-MRNPGGSLLHTLPRALQHAGRPGGAEQPGRWAPERTAGGDCSEDRLPRGGGAS--AAAAAAAASGALLGAYLERHGPPAASDLPAPAGALAGGPGSGGG-VVVGVAEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALV----RRYLQHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGFVLG-MGLMVVGVLIGTFIAHVVCKRLLTAWVAARIQSSDKLSAVIRVVEGGSGLKVVALARLTPIPFGLQNAVF--SITDLSLPNYLMASSVGLLPTQLLNSYLGTTLRTMEDVIAEQS--VSGYFVFCLQIVISIGLMFYVVHRAQVELNAAIVACEMELKTSLVKGSQPNPSGSSFYNKRTLTFSGARSIRLRESHTTVHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U145-1", "uniprot_id": "TMM64_MOUSE", "id": "Q3U145-1", "name": "Transmembrane protein 64", "aln": "-MRNPGGSLPHTLPRALQHAGRTGVVEQPGRWAPERTAGGDRSEDRLPRGGGASAAAAAAAAAASGALLGAYLERHGLPAASDLPAPAGALAGGPGSGGG-VVVGVAEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALV----RRYLQHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGFVLG-MGLMVVGVLIGTFIAHVVCKRLLTAWVAARIQNSDKLSAVIRVVEGGSGLKVVALARLTPIPFGLQNAVF--SITDVPLPSYLMASSAGLLPTQLLNSYLGTTLRTMEDVIAEQS--LSGYFVFCLQIVISIGLMFYVVHRAQVELNAAIVACEMELKTSLVKGNQSDPSGSSFYNKRTLTFSGG-GINIV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6YI46-1", "uniprot_id": "TMM64_HUMAN", "id": "Q6YI46-1", "name": "Transmembrane protein 64", "aln": "-MRSPGGILLQALPRLLQHAALPGLAELPARWALPRGAGGDGPADRLPRGGGAS--AAAAAAAASGALLGAYLERHGPPEASELPEPGGALAGGPGSGGGGVVVGVAEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALV----RRYLHHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGFVLG-MGLMMVGVLIGTFIAHVVCKRLLTAWVAARIQSSEKLSAVIRVVEGGSGLKVVALARLTPIPFGLQNAVF--SITDLSLPNYLMASSVGLLPTQLLNSYLGTTLRTMEDVIAEQS--VSGYFVFCLQIIISIGLMFYVVHRAQVELNAAIVACEMELKSSLVKGNQPNTSGSSFYNKRTLTFSGG-GINVV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LU94-1", "uniprot_id": "Q1LU94_DANRE", "id": "Q1LU94-1", "name": "", "aln": "-MWSSGP--VQGVLKALKHAAGKGHIQLS-RWLQRTPDSLDCDKIDILI-------CNVFDERANGGKTDAD------PAG--LTEPASSFT--------------PEFR--HPCCI-TTCCFKSALLACVLTAVCFSSVALV----RQYLKDVLLWVESLDSLVGAMLFIVGLITVSFPCGWGYIVLNVAAGYLYGFVLG-MGLVMVGVLIGTFIAHVVCKRLLTNWVLSKIGSSEQLSAVIRVVEGGSGLKVVALARLTPIPFGLQNAVFSVSITDVSLPNYLVASSVGLLPTQLLNSYLGTTLRTMEDVIAEQS--ISGYFVFSLQIFISIGLMFYVVHRAQVELNAAIAACQMEMKTSYMNGSAANHGGSTYCSKRTAATGGG--INVV--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNR8-1", "uniprot_id": "Q9VNR8_DROME", "id": "Q9VNR8-1", "name": "VTT domain-containing protein", "aln": "MSCNNNNNYKNKTTYGYSNNNDTNCIMQKPVPASTAPAFPQLIQASCSNAVEVD---PPDSIVGAAGNSEALFAAQRTPDTSEDSECDPFLASRRATRSSATTSVLHNRKRNSCWGRAHSFLTRNWYLGCLVPATILGALVFIGWATRDYARQLLFWIEMQNAWITFAVYMGLFALVSFPVVVGYFVLLITAGYLFGCLRG-WVTVILGANIGIAVAHATIRSCRHRIPVQRLIKNDTGRAILRVISGPKAFRVVLFTRLTPIPFGVQNVIFG--ISSINTRDYHVATLIGLLPAQTINVYLGSTLRSMHEVLSDNDTKLTGYISFLFEVICGVALMFWVLQKARKELSETLLSADYNNE-----GKHPDVQV----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36164-1", "uniprot_id": "TVP38_YEAST", "id": "P36164-1", "name": "Golgi apparatus membrane protein TVP38", "aln": "------------MSQSYEAGNANMGQGEDDEFDGYFEDFDNDIMPNSNNGQRVG------TNAGLSFNDEVNVNDDDFLDIYNMSPRERLMHN-----------IRKNVQKLQFYFYSLRLWQQIIIVLLGIMLMIMGILLLVFHN-AILHKVVVTSNDLREKMSTHFILMVLIFFVAFPPMIGYSLLSTTTGLIYGVSFEGWVTLALGSVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQENNSYWILALLRLCPFPYSLTNGAIA-GVYGISVRNFSIAN-IITTPKLFIYLFIGSRVKSLAESESTGS--RVFDLVSIIITLLILSLTAWLLYFKTKKRYLELQNRDRQVSTDQLPELSFEV------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . : : : : : : :. : :: : :: : : : : : *:** ** :* ::* ::* : :* * :... : : . *: ::. .. :: : ** *:*:.: * : : .: .: :*. * : ::*: :::: : : . : : . :.* ::: : : : : . : ", "identical_positions": 20, "similar_positions": 86, "identity": "4.99%" }, { "cls_id": "homologset.agr.MGI:2140361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZPC4-1", "uniprot_id": "A0A8I5ZPC4_RAT", "id": "A0A8I5ZPC4-1", "name": "", "aln": "------------------MAEVHRRQHAPVKGEAPAKSS--THRDEEELGMAPAETLTVFLKLL-AAGFYGVSSFLIVVVNKSVLTNYRFPSSLCVGLGQMVATVAVLWVGKALRVVKFPDFDRNVPRKTFPLPLLYFGNQITGLFSTKKLNLPMFTVLRRFSILFTMFAEGALLKKTFSWGIKMTVFAMIIGAFIAASSDLAFDLEGYVFILINDVLTAANGAYVKQKLDSKELGKYGLLYYNALFMILPTLAIAYFTGDAQKAMEFEGWADALFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIGMVFGGDYIFTWTNFIGLNISIAGSLVYSYITFTEEQLSKQSETSNKLDTKGKGAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AKQ0-1", "uniprot_id": "S35D1_MOUSE", "id": "A2AKQ0-1", "name": "Nucleotide sugar transporter SLC35D1", "aln": "------------------MAEVHRRQHAPVKGEAPAKSS--THRDEEELGMAPAETLTVFLKLL-AAGFYGVSSFLIVVVNKSVLTNYRFPSSLCVGLGQMVATVAVLWVGKTLRVVKFPDFDRNVPRKTFPLPLLYFGNQITGLFSTKKLNLPMFTVLRRFSILFTMFAEGALLKKTFSWGIKMTVFAMIIGAFVAASSDLAFDLEGYVFILINDVLTAANGAYVKQKLDSKELGKYGLLYYNALFMILPTLAIAYFTGDAQKAMEFEGWADTLFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIGMVFGGDYIFTWTNFIGLNISIAGSLVYSYITFTEEQLSKQSEASNKLDTKGKGAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTN3-1", "uniprot_id": "S35D1_HUMAN", "id": "Q9NTN3-1", "name": "Nucleotide sugar transporter SLC35D1", "aln": "------------------MAEVHRRQHARVKGEAPAKSS--TLRDEEELGMASAETLTVFLKLL-AAGFYGVSSFLIVVVNKSVLTNYRFPSSLCVGLGQMVATVAVLWVGKALRVVKFPDLDRNVPRKTFPLPLLYFGNQITGLFSTKKLNLPMFTVLRRFSILFTMFAEGVLLKKTFSWGIKMTVFAMIIGAFVAASSDLAFDLEGYAFILINDVLTAANGAYVKQKLDSKELGKYGLLYYNALFMILPTLAIAYFTGDAQKAVEFEGWADTLFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIGMVFGGDYIFTWTNFIGLNISIAGSLVYSYITFTEEQLSKQSEANNKLDIKGKGAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N1V5-1", "uniprot_id": "A0A8M1N1V5_DANRE", "id": "A0A8M1N1V5-1", "name": "", "aln": "-----------------------------------MKQC--EARN-EAAGMA-DQTLTVLLKLS-AAGFYGISSFLIVVVNKSVLTNYRFPSSICVGIGQMLATVVVLRVGKALRVITFPEFDGSIPRKTFPLPLLYVGNQITGLFGTKRLNLPMFTVLRRFSILFTMLAEGFLLKKKFSRPVQLTVFTMILGAFVAASADLAFDLQGYVFILMNDVLTAANGAFVKQKLDSKELGKYGLLYYNALFMILPTLLLAHVTGDMDKAFDYDGWSDVLFISQFFLSCIMGFILMYSTVLCTQYNSALTTTIVGCLKNILVTYIGMVFGGDYIFSWTNFIGLNISIAGSLVYSYITFTEEQITKQSENTNKLEVKGKVAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9QF41-1", "uniprot_id": "E9QF41_DANRE", "id": "E9QF41-1", "name": "", "aln": "--------------------------MANARARRSAGTP--GKRGKHEVSGEDEDTSALYLKLF-AAAFYGISSFLIVVVNKSVLTNYRFPSSLALGIGQMFATVVVLRGAKALNVISFPDFDWHVTYKVFPLPLLYVGNQLTGLFGTKQLNLPMFTVLRRFSILFTMLFEGYLLKQKFSWSIKATVFTMILGAFVAASSDLAFDLQGYVFITLNNILTAANGAYMKQKLDSKELGKYGLLYYNALLMIIPTVVLAYFTGDVQKTLECEVWADYFFVIQFVLSCVMGFILMYSIMLCTHYNSALTTTIVGCIKNILVTYIGMVFGGDYIFSWMNFVGLNISIAGSLVYSYITFTKEQK-KTS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95YI5-1", "uniprot_id": "US74C_DROME", "id": "Q95YI5-1", "name": "UDP-sugar transporter UST74c", "aln": "MSMSRGGNTTLDLQPLLAESDVGNRELEEKMGGSADRSSLLDGSGSKELSHREREDSALFVKKIGSALFYGLSSFMITVVNKTVLTSYHFPSFLFLSLGQLTASIVVLGMGKRLKLVNFPPLQRNTFAKIFPLPLIFLGNMMFGLGGTKTLSLPMFAALRRFSILMTMLLELKILGLRPSNAVQVSVYAMIGGALLAASDDLSFNMRGYIYVMITNALTASNGVYVKKKLDTSEIGKYGLMYYNSLFMFLPALALNYVTGNLDQALNFEQWNDSVFVVQFLLSCVMGFILSYSTILCTQFNSALTTTIVGCLKNICVTYLGMFIGGDYVFSWLNCIGINISVLASLLYTYVTFRRKRAPDKQD--HLPSTRGENV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : :: :* :* ***:***:*.****:***.*:*** : :.:**: *::.** .* *.::.** :: * *****::.** : ** .** *.****:.*******:**: * :* * :: :*::** **::*** **:*::.** :: :.: ***:**.::*:***:.*:*****:***:*:*::*:: : :.**: :::.: : * * .*: ** ***:***** *: :***::***********:*** :**:**.:****:*:* * :*:***: .**:*:*:** .:: . . ", "identical_positions": 146, "similar_positions": 107, "identity": "38.83%" }, { "cls_id": "homologset.agr.MGI:2140364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K017-1", "uniprot_id": "B0K017_RAT", "id": "B0K017-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "MAAAAAAAAAAMTAAGGGGAGAARSLSRFRGCLAGALLGDCVGAVFEAHDTVSLTSVLSHVQSLEPDPGTPGSARTETLYYTDDTAMTRAMVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGVITVFKKLLNPKCRDVYEPARAQFNGKGSYGNGGAMRVAGIPLAYHSVQDVQKFARLSAQLTHASSLGYNGAILQALAVHLALQGVSSS-EHFLEQLLGHMEELEGDAQSVLDAKELGMEERPYSSRLKKVGELLDQDAVSREEVVSELGNGIAAFESVPTAIYCFLRCMEPDPEIPSTFNSLQRTLIYSISLGGDTDTIATMAGAIAGAYYGVEQVPESWQQSCEGYEETDVLAQSLHRVFQESP----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG72-1", "uniprot_id": "ADPRS_MOUSE", "id": "Q8CG72-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "MAVAAAAAATAMSAAGGGGASAARSISRFRGCLAGALLGDCVGAVYEAHDTVSLASVLSHVESLEPDPGTPGSARTETLYYTDDTAMTRALVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGVITVFKKLLNPKCRDVYEPARAQFNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQLTHASSLGYNGAILQALAVHLALQGVSSS-EHFLEQLLGHMEELEGDAQSVLDAKELGMEERPYSSRLKKVGELLDQDVVSREEVVSELGNGIAAFESVPTAIYCFLRCMEPHPEIPSTFNSLQRTLIYSISLGGDTDTIATMAGAIAGAYYGMEQVPESWQQSCEGFEETDVLAQSLHRVFQESS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX46-1", "uniprot_id": "ADPRS_HUMAN", "id": "Q9NX46-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "------MAAAAMAAAAGGGAGAARSLSRFRGCLAGALLGDCVGSFYEAHDTVDLTSVLRHVQSLEPDPGTPGSERTEALYYTDDTAMARALVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGVVTVFKKLLNPKCRDVFEPARAQFNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQLTHASSLGYNGAILQALAVHLALQGESSS-EHFLKQLLGHMEDLEGDAQSVLDARELGMEERPYSSRLKKIGELLDQASVTREEVVSELGNGIAAFESVPTAIYCFLRCMEPDPEIPSAFNSLQRTLIYSISLGGDTDTIATMAGAIAGAYYGMDQVPESWQQSCEGYEETDILAQSLHRVFQKS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HT8-1", "uniprot_id": "ADPRS_DANRE", "id": "Q66HT8-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "------MSAAARVVAP------VMMLSRFRGALVGSVLGDCIGGEFEGAVDVPLDRVLQHLSALEDDTRGDG-----ILQYSDDTAMMRCVADSLLTRMTFDERDMAQRFAKEYSHSPGRGYGSGVVQVLRKLASPHLKDVFQPAQAQFGGRGSFGNGGAMRAVPFALAFRSRADVRKYSRFGAMLTHSCSLGYNGAALQALAVHLSLQGALALPKDFIDKLISEMEELEKDETAKHDAKALNLSEFPYCSRLHRVKELMDKTSVSIEEVISELGNGIAALQSVPTAIFCVLYCLEPQDGLPERFGGLERTIAYSLALGGDTDTIACMAGAIAGAHYGIDSIPLSWQVSCEGVDEADDLARRLYDLYCLPQHNEDRGNNQPHTTNTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* .* . :*****.*.*::****:*. :*. * * ** *:.:** *. * * *:***** *.:.:***:: :*** ***:***:**.:.*.****:**: *::** .*: :**::**:***.*:**:*******.. :.**: * **:*::*:.* ***:.******* ********:*** : :.*:.:*:..**:** * : **: *.:.* **.***::: **:*: *: ***:*********::******:*.* *:**. :*. *..*:**: **::********* ********:**::.:* *** **** :*:* **: *: :: . ", "identical_positions": 186, "similar_positions": 106, "identity": "48.06%" }, { "cls_id": "homologset.agr.MGI:2140367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBR8-1", "uniprot_id": "B1WBR8_RAT", "id": "B1WBR8-1", "name": "F-box/LRR-repeat protein 4", "aln": "---------------MSPVFPMLTVLTMFYYMCLRRRARTATRGDMMSSHRTIVSNSRTS-PLNAEVVQYAKEVVDFSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTAVFRTYGTWWDQCPSASLPFR-RTPSSFQSQDYVELTFEQQVYPTAVHVLETYHPGAVIRILACSANPYSPNPPAEVRWETLWSERPTKVNAS---QARQFKPRIKQINFPTNLIRLEVNSSLLDYYTELDAVVLHGTKDKPLLSL-KTALVDMN--------------------------DLEDDDYEEKDGCEMDALNKKFSSATLGDGPSNGYFD-----------KLPYELIQLILNHLSLPDLCRLAQTCRLLHQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQARCALVQWLNLSWTGNRGFISVSGFSRFLKVCGSELVRLELSCSHFLNDACLEVISEMCPNLQDLNLSSCDKLPPQA-FGHIAKLRSLKRLILYRTKVEQTALLSILNFCAELQHLSLGSCVMIEDYDVIASMIGAKCKSLRTLDLWRCKNITENGIAELASGCALLEELDLGWCPTLQSSTGCFARLARQLPNLQKLFLTANRSVCDTDIEELASNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKVFIKKSFTQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH70-1", "uniprot_id": "FBXL4_MOUSE", "id": "Q8BH70-1", "name": "F-box/LRR-repeat protein 4", "aln": "---------------MSPVFPMLTVLTMFYYMCLRRRARTATRGDMMNSHRTIVSNSRTS-PLNAEVVQYAKEVVDFSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTAVFRTYGTWWDQCPSASLPFR-RTPSSFQSQDYVELTFEQQVYPTAVHVLETYHPGAVIRILACSANPYSPNPPAEVRWEILWSERPMKVNAS---QARQFKPCIKQINFPTNLIRLEVNSSLLDYYTELDAVVLHGTKDKPLLSL-KTALVDMN--------------------------DLEDDDYEEKDGCEMDALNKKFSSAALGDGPHNGYFD-----------KLPYELIQLILNHLSLPDLCRLAQTCRLLHQHCCDPLQYIHLNLQPYWARLDDTSLEFLQARCVLVQWLNLSWTGNRGFISVSGFSRFLKVCGSELVRLELSCSHFLNDTCLEVISEMCPNLQDLNLSSCDKLPPQA-FGHIAKLCSLKRLVLYRTKVEQTALLSILNFCAELQHLSLGSCVMIEDYDVIASMIGAKCKNLRTLDLWRCKNITENGIAELASGCVLLEELDLGWCPTLQSSTGCFVRLARQLPNLQKLFLTANRSVCDTDIEELASNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNKAVLELNASFPKVFIKKSFTQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKA2-1", "uniprot_id": "FBXL4_HUMAN", "id": "Q9UKA2-1", "name": "F-box/LRR-repeat protein 4", "aln": "---------------MSPVFPMLTVLTMFYYICLRRRARTATRGEMMNTHRAIESNSQTS-PLNAEVVQYAKEVVDFSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTAVFRTYGTWWDQCPSASLPFK-RTPPNFQSQDYVELTFEQQVYPTAVHVLETYHPGAVIRILACSANPYSPNPPAEVRWEILWSERPTKVNAS---QARQFKPCIKQINFPTNLIRLEVNSSLLEYYTELDAVVLHGVKDKPVLSL-KTSLIDMN--------------------------DIEDDAYAEKDGCGMDSLNKKFSSAVLGEGPNNGYFD-----------KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQA-FNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKVFIKKSFTQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N367-1", "uniprot_id": "A0A8M1N367_DANRE", "id": "A0A8M1N367-1", "name": "", "aln": "------------------MFPMLTLLSMFYYICLRRRSRSGTRSEALGSRRAVELGQRSALPVTVEVEQYGKEILDFSSHYGSENSMSYTMWNLAGVPNVYPSSGDFTQTAVFRTYGTWWEQCISSTPRFR-RTPPSFHSQDYLELAFEEPVYPTAVEVLETYHPGAIVKIMACSLNPFSQNPPTDVRWEVLWSGKPNKALTP---QARQFSPNIKQISFTTNLLRLEVNSSLLDYYTELDAVILRGVRERPILALYKIPVIDIN--------------------------DLSDSEEEISEAGGLCCR----STAENRQSLANGYFD-----------RLPYELIQLIVSHLPVPDLCRLAQSCKLFHKHCCDPLQYIQLSLQPYWARLTDASLCHLQSRCTLLQRLNLSWTGNRGAVTPAGFCSFMKACGASLVCLEVSCCHFLTEACLEVITQTCPCLQELNLASCDRLQPQA-FNHIAKLTHLRRLVLYRTKVEQSAILSILTFCPELRHLNLGSCVMIEDYDVVVSMLSARCRSLRSLDLWRCRNLSERGLAELVSGCRLLEELDLGWCSTLQSSSGCFQHLARSLPRLRKLFLTANRTVCDADLEELAANCSALQHLDILGTRMVSSASLRKLLQCCPRLKLLDVSFCSQIDSRFVQELNGLFPNVSIKKSFTQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY46-1", "uniprot_id": "Q9VY46_DROME", "id": "Q9VY46-1", "name": "", "aln": "MSLLAYGEPAESSETDSPAAEAEPDVLVDFTAMLQRQRQNGDYGGWFGCDSKMQTTQSDQ---GYYLEQYVLGVLDFSSQYGIDYSISYTAANVIGRPTKFPAYGDYPETFPMRTYGDWWQRAPSATREIQPQNLPKLETHDYVVVYFEEFVVPTEVAIFETFNPGAVVRIWAYGLTKN---------WTCLWEATESDLSRPPPLDSRRFAPSLKKTTMLTKTLRIDFNHSRLNYYTEIDAIMLCGRTVTKTQNLLAKQQITQHSRTLVSPPPDAIGSTSGDGSGGSISHKLRTLKFQPNCGEDGATKLHEFINNDLSQFLADNCVDGEAAAPQICLTDLPFEILLRILSYLDLKSLFRVGHVSRTFYDISRHPLLYAEISLKPYWDVASSELLCTLARRATMLRKLDLSWCGGFGNVSPTEFKKFLTQRGDNLTHLRLNSCKFLNASCIENVGIVCDNLIELSLRNCATEPPLLNFSCLANLKNLERLDLFQTYFETELLLSMLEGNRKLKHLNLAFCGVSVNMDNVAAHLATYNTQLISLDLWKAHFLSSRGLQSLAR-LHQLEELDLGWCMREASLGDGLFQLLSNCPKLKKLFLSAVRGTTERDLMHIAALGKNLEQLDLMGILNITHERVYDILVNCPKLQLLDLSFCDNIMDRDFDLLAEWSRQFKVDIKSSRRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : *:*: :.. . :. : . : ** ::****:** : *:*** *: * *. :*: **:.:* :**** **::. *:: :: :. ..:.::**: : **: * ** * ::**::***:::* * . . * **. . . ::*:* * :*: .: *: :*::.* * *:****:**::* * * : : .: . . . : :. .* **:*:: *:.:* : .* *:.: .: : . . .** * .:.*:*** . * * *..::: *:*** *. * :: : * *:. * .*. *.:...:**. :*:* : * * *.* .* * *. :*:* *.** *::* .* :**:* :*:**.*. * : : * :.: :.: .* :****:.: ::..*: .*. ********* * . : :* . *.*:****:* * . : *: .:*. . *::**::* :: : .:* * *.***:***.:* .: . * :. :. . :: ", "identical_positions": 164, "similar_positions": 203, "identity": "24.05%" }, { "cls_id": "homologset.agr.MGI:2140368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7C0-1", "uniprot_id": "GPN2_RAT", "id": "D4A7C0-1", "name": "GPN-loop GTPase 2", "aln": "---MA-----GAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLD-WLRAKLEPLRG--HYFLFDCPGQVELCTHHTSLRSIFSQMAQW-DLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYG-KLAFNLDYYTEVLDLSYLLDHLA---SDPFFSHYRQLNEKLVQLIEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQR----SLEALMSAAVGADFHFSS-------------------------------TLGIQEKYLASSDQTAEQEAMQL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEJ1-1", "uniprot_id": "GPN2_MOUSE", "id": "Q8VEJ1-1", "name": "GPN-loop GTPase 2", "aln": "---MA-----GAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANDGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLD-WLRAKLEPLRG--HYFLFDCPGQVELCTHHTALRSIFSQMAQW-DLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYG-KLAFNLDYYTEVLDLSYLLEHLA---SDPFFRRYRQLNEKLVQLVEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQR----SLEAMMSAAMGADFHFSS-------------------------------TLGIQEKYLAPSEQTAEQEAMQL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9Y4-1", "uniprot_id": "GPN2_HUMAN", "id": "Q9H9Y4-1", "name": "GPN-loop GTPase 2", "aln": "---MA-----GAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLD-WLRAKLDPLRG--HYFLFDCPGQVELCTHHGALRSIFSQMAQW-DLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYG-KLAFNLDYYTEVLDLSYLLDHLA---SDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVDKANGYCFRAQEQR----SLEAMMSAAMGADFHFSS-------------------------------TLGIQEKYLAPSNQSVEQEAMQL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PUR6-1", "uniprot_id": "GPN2_DANRE", "id": "Q6PUR6-1", "name": "GPN-loop GTPase 2", "aln": "--MMS-----SDPPSLRFGQVVIGPPGSGKTTYCRGMQEFLSRLGRKVVIVNLDPANEGLPYPCAVDIAELVTLDDVMDGLKLGPNGGLIYSMEYLEANLD-WLENKLKLHHD--CYFLFDCPGQVELYTHHNSVKNIFAQLSKW-NFRLTAVHLVDSHYCADPAKFISVLCTSLSTMLHVELPHVNVLSKMDLIEQYG-KLAFNLDFYTEVLDLSYLVEHLS---ADPFFRNFNHLNVKLAEVIQDYSLVSFVPLNVQDKESMMQVLRTVDKANGYCFGDLEER----NLQAMMSAAVGADFQFST-------------------------------TLGVQEKYLDATKNHVEDEVMDL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU67-1", "uniprot_id": "Q9VU67_DROME", "id": "Q9VU67-1", "name": "GPN-loop GTPase 2", "aln": "--MMQRFPTQATVENPRYGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCMEHLKLGPNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLERE-RYSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYYTDVLDLKYLLDKLD---DDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKANGYVYKAGEEQ----TVNSLLACAVGAETEAAR-------------------------------MEHDVQPYME---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08726-1", "uniprot_id": "GPN2_YEAST", "id": "Q08726-1", "name": "GPN-loop GTPase 2", "aln": "MP---------------FAQIVIGPPGSGKSTYCNGCSQFFNAIGRHSQVVNMDPANDALPYPCAVDIRDFITLEEIMQEQQLGPNGGLMYAVESLDNSIDLFILQIKSLVEEEKAYLVFDCPGQVELFTHHSSLFNIFKKMEKELDIRFCVVNLIDCFYMTSPSQYISILLLALRSMLMMDLPHINVFSKIDMLKSYG-ELPFRLDYYTEVQDLDYLEPYIEKEGSSVLGKKYSKLTETIKELVSDFNLVSFEVLSVDDKESMINLQGVIDKANGYIFGASEVGGDTVWAEASREGALIANYDIQDRWIDNKEKYDKEEEEKRTALLKEQELQNKAVDVNEEDEWENALKEWEEKQGMDFVR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* :********:*** :* :**: :**:****: :.* .:.: ::: : : *: :*****.*::. * * :: :: *::********* *** :: ** :: : : .*:*:*..* :.*:::*: * :* :** :.***:*::** *::: : :* *.:*:**:* **.** : . .: :*. : .::.*: **** *.: ..:*: .: :****** : * :: *: *: . : : ", "identical_positions": 90, "similar_positions": 96, "identity": "24.79%" }, { "cls_id": "homologset.agr.MGI:2140371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCV5-1", "uniprot_id": "M0RCV5_RAT", "id": "M0RCV5-1", "name": "AP-4 complex accessory subunit RUSC2", "aln": "MPLLEISRMDSPPKLTGETLIVHHIPLVHCQVPD-RQCCGGAGGGGRGTRANPF-CPPELGLTQ----PDQDLGQADSLLYTSLHSAPGAPTRSSDGVKS--------RSRDGRGPGAPKRHNPFLVQEG---------------------VGETGLGDLHDGSTGDGATQQSFHLHSTSQP---FHLSSFQLPPSGPGQGRPWGAARSRPGVVEGQEQDPATTLGT-QCSNSHCCRP---EPEAETMELDECGGHGGSGSGGGNNDISGFSFEQEWKLSSD-ESPRHPGRSGS------GAQHCHCSSTSSQS-----EAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMH----GSPRANLN-SVPQSCSDSS-----FCS---HADPGAFYLDLQPSPAESRMSCESHHPESGDREEGCGCPHASSPELDANCNAYR------PHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGSDPDPSQPSEYYLFQKP----EEQEAVGSSTEAATTMG---PTVLEGQVYTNTSPPN--------LSTGRQRSRSYDRSLERSPAVRLGSLERMLSCPVRLSEGPGALAGPASPPRRVTSFAELAKGRKKAAGSGSP----PLRVSIGESSQEFSPIQEAQQDRAGPLDEGTRCSHSLPSMPLGPSLDLLGPEP---WSTQVCQDPQSSEMLLPSLRASGQGLLAQPMDPVPALLGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRAQQPAPLVISTAQGSAPAPSGEPQAFPSQTTGRGARNAGPEPETSRPSPLGSYSPVRSAGP---FGSSTDSSASTSCSPPPEQATASESLRPWSHPCPP------------PVRPATSQQPRKEDQKIPTLAEYRLHG--TGSLPPLGSWRSGFTRTESLARGGGE-------GSMASRPNNVNHLSPQALKWREYRRKNPL-------GPPGVSGSLDRRPQEARLAHRNPIFEFPGSFGTTNHLNCRLNGQIAKPLSLTCPDLQ-DPFSLTEKPPAEFCLSPDGNS-EAVSIDILQKRGLVKAVNTAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVQAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYDHEDIIQTHYQPWGFLRAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQNGRQQRQHKELLRVS-QDLLLSAHSTLQLARARGQEGPGDVDRAAPGE-----------------------RVKGVGASEGGEEDEDD-------SEEVAVVPGS----------------------SDHGKWARGGQAGWWYQLMQSSQVYIEGTAEGSRFPRSSSSSSGGG-EKKKGAGGGGPSQTPPPPPREGVVEGAEACPAPEEALGQ---------------------------ERGWPFWMGSPPDSVLAELRRSREREGPVAPPTENE-GTPEPSPGG----IKWGHLFGS------RKAQREARPTNRLPSDWLSLDKSVFQLVAQTMGARREPEPR-------------ENLQESHPPAVPSKPPCEVQALCHHLATGPGQLSFHKGDILRVLGPAGGDWLCCSRGPDTGLVPLAYVTLTPTPSSP-GNSQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U22-1", "uniprot_id": "RUSC2_MOUSE", "id": "Q80U22-1", "name": "AP-4 complex accessory subunit RUSC2", "aln": "--------MDSPPKLTGETLIVHHIPLVHCQVPD-RQCCGGAGGGGGGTRANPF-CPPELGLTQ----PDHDLGQADSLLYPSLHSAPGAPTGSSDSVKS--------RSRDGRGPGAPKRHNPFLVQEG---------------------VGETGLGDLHDSSTGDSVTQQSFHLHSASQP---FHLSSFQLPPSGPGQGRPWGATHSRPGVVEGQEQDPATALGT-QCSTSHCCRP---ELEAERMELDECGGHGGSGSGGGTSDISGFSFEQEWKISSD-ESPRHPGRSGS------GTQHCHCSSTSSQS-----EAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMH----SSSRANLN-SVPQSCSDSS-----FCS---HADPGAFYLDLQPSPAESRMSCESHHPENGDREEGCGCPHVSSPELDANCNAYH------PHSEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPCPDPDPNQPSEYYLFQKPDIQPEEQEAVGSPAEAATAMG---PTVLEGQVYTNTSPPN--------LNTGRQRSRSYDRSLERSPPVRLGSLERMLSCPVRLSEGPAALAGPASPPRRVTSFAELAKGRKKAAGSGSP----PLRASVGDSSQEFSPIQEAQQDRAAPLDEGTRCSHSLPSLPLGPSLDLLGPEP---WSTPVCQGSQSSEMPLPSLRAAGQGPLAQLMDPGPAFSGSPATSHTQRDSRARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRAQQPAPLVISTAQGPAPAPSGEPQPFTSQASGRGARNAGPEPETSRPSPLGSYSPVRSAGP---FGSSTDSSASTSCSPPPEQGTAADSVSPWSHTCPP------------TVRPATSQQPPKEDQKIPTLAEYRLHG--TGSLPPLGSWRSGFTRAESLVRGGGE-------GSMANRPNNANHLSPQALKWREYRRKNPL-------GPPGLSGSLDRRPPEARLARRNPIFEFPGSFGTTSHLNCRLNGQISKPLSLTCPDLQ-DPFSLTEKPPAEFCLSPDGNS-EAISIDILQKKGLVKAVNTAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVQAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWGFLRAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGRQQRQHKELLRVS-QDLLLSAHSTLQLARSRGQEGPGDMDRVAPGE-----------------------RVKGVGASEGGEEDEED-------AEEVAVVAGS----------------------SDHGKWARGGQAGWWYQLMQSSQVYIDGTAEGSRFPRSSSSSSGSGSEKKKGVGSGGPSQAPPPPPREGVVEGAEACPAPEEALGQ---------------------------ERGWPFWMGSPPDSVLAELRRSREREGPVAPPTENEEGTAEPSPGG----IKWGHLFGS------RKSQREARPTNRLPSDWLSLDKSVFQLVAQTMGARREPEPR-------------ENLQESHPPAVPSKPPCEVQALCHHLATGPGQLSFHKGDILRVLGPARGDWLRCSRGPDTGLVPLAYVTLPPTPSSPPGSSQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N2Y8-1", "uniprot_id": "RUSC2_HUMAN", "id": "Q8N2Y8-1", "name": "AP-4 complex accessory subunit RUSC2", "aln": "--------MDSPPKLTGETLIVHHIPLVHCQVPD-RQCCGGAGGGGGSTRPNPF-CPPELGITQ----PDQDLGQADSLLFSSLHSTPGGTARSIDSTKS--------RSRDGRGPGAPKRHNPFLLQEG---------------------VGEPGLGDLYDDSIGDSATQQSFHLHGTGQPN--FHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTLDTQQCGTSHCCRP---ELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSD-ESPRNPGCSGS------GDQHCRCSSTSSQS-----EAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMH----GTPRANLN-SAPQSCSDSS-----FCS---HSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELDANCNSYR------PHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVG---PTVLEGQVYTNTSPPN--------LSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSP----PLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGP---FGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPS------------AVRPATSQQPQKEDQKILTLTEYRLHG--TGSLPPLGSWRSGLSRAESLARGGGE-------GSMATRPSNANHLSPQALKWREYRRKNPL-------GPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPDFQ-DPFSLTEKPPAEFCLSPDGSS-EAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWGFLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVS-QDLLLSAHSTLQLARARGQEGPGDVDRAAQGE-----------------------RVKGVGASEGGEEEEEEE-----ETEEVAEAAGG----------------------SGRARWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNS---SSEKKKGAGGGGPPQAPP--PREGVVEGAEACPASEEALGR---------------------------ERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGG----IKWGHLFGS------RKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPK-------------ESLQEPHSPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTLTPTPSPTPGSSQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCE9-1", "uniprot_id": "A0A8M2BCE9_DANRE", "id": "A0A8M2BCE9-1", "name": "", "aln": "--------MDSPPKLAGETLIVHHIPLVHCQVSSSRKCCG----SSLKRNSNPFSCPENLGLSRTTSLPERDILQREALVYSSLIQTSSSSLSSSDTFGDGGMRVGEKRGRGGREGSMASDTSSFTSSNSEDHAQSLSMKTHERPRRNPFLLNTEDEDDEDEDNLNGYLEDSSFHLHGNLHEISNAMLSNEDLPP---FHLHDLGFTAEPFLLHESTEKQWCSTNGPSREAESRDHKSGTFDLSTHMEGLNMLRLDSQRRHGSSGSTLSMDCGEQEWGEDDDYEDHSMQGGRGSSESSSLAAPHCSCCGLSQPYSEPFQEFSECHQGYGSDSSCNSSDGVLVNFSTIYNKMNNVVPAKQSLNINSSTEQSCASSVSELVGMCGTECSSGRGAFYLDLHTSPVEPPQHPLATQEHANS--SSISQQQGATLEVDANCNSYHNILGSEGLSSAETSANDLTSCLQSQARLVVATQNYYKLVTCDLSSQSSPSPVGSSVTSCSDEHSKGSP----------AQPTEYYLFQQMKEDEEEEDTELNEENDPTDIDSIHENVIEGQVYINISPPTTACNSVAASGSSRPRSRSYDRNLDKSPSPRLGSLERMLSCPVRLSESADPSP---PPPPRVTSFAEIARNKRRTGGSPSQRSGIEATSTHSHSSGEFSPILEG-------LPEGQ--SHSLPPLTR-------------------CHSQGSCDLS------SSYRPWSTPLRESPGGMGRQTRSKAEGGLSSSTDS----SPTVIRYSKDQRPTSLPIQPFTFQHQFGKPQAKP-------ILPLLDGYISQMQSR---------GAAAPEGDED--DSEEHHRPAHGTSNTPTTVRPSPLGSYSPIRLQGAPTSSGNCSTCSPTLNGPRPPRSLSCPISAGLLPQHTPPGVAIHTETPKLAPLPPTPPPAPLMKQSPLMPALPTRNHCFHRGNLPALPS--SGLSPLGQLEPAPQEEPVKVLPACVTQRQPNVHHLSPQALKWREYRRKNPLGVERCKDGPHSFSCSLETKRPGTRVMRRN-VFDFPPTNQALSFG--RLNGQSLRQLPQCYSDFLPDYFSQTERPPEEFCLSPDAHTDESISIDLLQKRGLVKAINTAVDLIVAHFGTSRDAGVKAKLGNSSVSPNVGHLILKYLCPAIREILNDGLKAYVLDLIIGQRKNQPWSVVEASTQLGPSTRVLHSLFSKVSQYSELTNHSMRLNAFIFGLLNLRSLEFWFNHIYTHEDIIAAHYHPWGFLPLSQGACQPLFEELMLLLQPLSLLPFDLDLLFEPHQLQKGEEHLRRKEQLCSARQSLDQSDRSTFQLMRGCGMLESQETGMLPQRESFVLRDEECRLRTEGVTLKMKQEWQRSVGAEREFRNKEDGVGKECLRKSDTGQMQGGGCCAARMKGVGEDNEKDKKREKDGDATKQRNRQAGWWYQLMQSSQVYIDNSAEGSKFVK---------WEKRRKGGVENHRQSHPP-PREGVVEGAEAIQQMDEQVEHGRTSSSNINSIGRGVLNQSALSEPTKATKAKPSWMGSPPESVLTELKKSKEKQPDCQDPNEGLQAQPEAEEDGTAQVLRWGRLFGAGNASKKEKIEQKSVRKQRLPSGWLSIDHSVLDLVAQSVGVRKRAEQQSFTSQSQESNLGPTEQAQTQSPQTKTLAPREVKALCHHIATEPGQLSFNKGDVLQVLSRADSDWLMCALGDSQGLVPIIYVTLIEDSQER------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:****************.. *:*** .. ..*** ** :**::: *::*: * ::*::.** .:.... * * . *.*.** . .. ..* .:. :. . .* :.. .. :.*****. : **. :*** : * : . : *. *:: : .. : . *: :. : .:. *: . *.. . * . :*** ..* *. * ** . ** *.. *. * :: ** *************.***:****: .. *:* *. ***:.* :*. :. *******:.** *. : : . .. . . : :: *:*****:*: ... .:. ***:*:*****************************.***:****:**:* ** **:******: **::: . : .: :. .*:***** * ***. .:.* *******.*::**. *****************.. . . .** *******:*:.::::.** * : ..** ***** *. * ** *****.:. *:. *.:: :. : : *. * : *::: . : :*. * .*:****:****:******.***:* * **. * *.* *. ..**.*: : .. * *: :. * * **********:* *. * .: .*.: . . **.. :.. * .: *. .: *:.. * ::. : . * * *.**.* * **:: .* . * ..:: * *.:****************** ** ..* **: : :*: :** :*:** : : .. ***** : *. .*: * ** **:** *******. : *::***:***:*****:* **************.******************:*******:: :*:*****:***:******* ***************:***.*:.****:.***.*:**:****:****:*********:* ***** :**:***** :: .* *****:******:****.*****: : **.*.:: ::** * : *.* * :**:** *. * . : . . * :.***.. .:.*: .:.. *. .. . *. ****************:.: ***:* : **:: * . *: * *********** :* : : :. * ******:***:**::*:*:: * *. . .*.. .* ::**:***: .* :::: .:****.***:*:*:::****::* *:..* : . :.:.* : .* **:*****:** ******:***:*:**. * .*** *: * . ****: **** .. ", "identical_positions": 654, "similar_positions": 401, "identity": "37.39%" }, { "cls_id": "homologset.agr.MGI:2140466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7G9-1", "uniprot_id": "D4A7G9_RAT", "id": "D4A7G9-1", "name": "", "aln": "MADPGVPDPFKRGTGNLGVQEAAGPGGALVELTPTPGGMALVSPYHTHRVGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQDQARKVLEDARRDADLHHVACNMVKKPGNIYYLYQRESGQKYFSIISPQVRTLAFNSESTPAFEKFWACLNENEWGAGCPHDFLGAYKLQHDMSWTPYEDVEKQDAKISMMDKLLSQPMALPPGTEPTFQG-LTH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5EBG8-1", "uniprot_id": "CA050_MOUSE", "id": "Q5EBG8-1", "name": "Uncharacterized protein C1orf50 homolog", "aln": "MADPGVPGRYESGTGNLGVKEAAGPGGALVELTPTPGGLALVSPYHTHRVGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDARRDADLHHAACNMVKKPGNIYYLYQRESGQQYFSIISPE------------------------EWGTGCPHDFLGAYKLQHDMSWTPYEDVEKQDAKIGMMDKLLSQPMALPPCTEPTFQG-LPH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV19-1", "uniprot_id": "CA050_HUMAN", "id": "Q9BV19-1", "name": "Uncharacterized protein C1orf50", "aln": "MEDAAAPGRTEGVLERQGAPPAAGQGGALVELTPTPGGLALVSPYHTHRAGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDAHRDANLHHVACNIVKKPGNIYYLYKRESGQQYFSIISPK------------------------EWGTSCPHDFLGAYKLQHDLSWTPYEDIEKQDAKISMMDTLLSQSVALPPCTEPNFQG-LTH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502G5-1", "uniprot_id": "CA050_DANRE", "id": "Q502G5-1", "name": "Uncharacterized protein C1orf50 homolog", "aln": "-MDRSVS---------LPHQPNKTTTVTLVETSSNPSGMVLVSPYQTNRVGDPMDLVSLAQQVQKGDEFIRANACNRLTVIADQIRYLQEQARKVLEDARKDAELHHAACNVVKKPGNMYYLYMRESGQRYFSILSPR------------------------EWGASCPHKFLGGYKLQHDMSWTPQEDVEKRDAEIGIMDKLLNRQTALPACTEPNFEG-LSQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INX1-1", "uniprot_id": "Q8INX1_DROME", "id": "Q8INX1-1", "name": "", "aln": "--------------MDELTYQTAVKKAQLVERNPQ----LQINPMRVS-MHQEEDIIELAQQIQNADKQLKNTTCQKLGVIMEQIKMLQAQAMEILKESTLNRDLHSAACNFTKKPGHIYHLYQRPSGQNYFSMLSPE------------------------EWSLSVDQTFKGSYRLEYDLSWTPLDKIKEQDEKLKWAEQCMLKALDGGRGSAMAIDFNISND", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** .. :.* :. : *:: **:*:*:.*: :: .: ::* ** :**: ** ** ::*::: : :** .***..****::*:** * ***.***::**. **. . : * *.*:*::*:**** :.::::* :: : : : : :: :.: ", "identical_positions": 53, "similar_positions": 64, "identity": "23.56%" }, { "cls_id": "homologset.agr.MGI:2140475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6APE1-1", "uniprot_id": "A0A8I6APE1_RAT", "id": "A0A8I6APE1-1", "name": "", "aln": "MPESGAWVLVQRRKGAGRPTRARSKRLRAWTSSLVRSSLSATPPPTLGSRLELRFRRVGAGGLAQHEGVLVPPLWKAMEKRLGVKPSTTSWVLPGYCWQISVKPPRSLYLVYSFFCLSVLWLSTDANESRCHQGKTLYGAGLKTEGENHLRLLPGSLSFQACWAACCQDP-----ACHALWWLEGMCLQADCSKPQSCQPFRTDSSHSVLIVFQKSQTAKDLGLLPEDGEPHLRR-GWGRTSWRRQSLPGAPLTLSIPSSDHQSLLRERQKRDHPSVVPTRVVIQQAKANHSEEASAASPRASAEVRKTITVPSSFTSNHTTQTPEWPKNVSIPTEPSGHFTLASS----TQQVKSTEHSPTDTPLPVAPSYSSATPTAQTSSQSTSAPRPVVK--ELVVSAGKSVQITLPKNEVQLNAFALP-EPEPGETYTYDWQLITHPT-DYSGEVERKHSQSLQLSKLTPGLYEFKVIVDGQN-AHGEGYVNVTVKPEPRKNRPPVAVVSPQFQEISLPTTSTIIDGSQSTDDDKIVQYHWEELKGPLREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTASLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGISSYEWSLSPSSKGKVVEMQGVRTPALQLSAMQEGDYTYQLTVTDTAGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSTDDQRVVSYLWEQSRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVSVIVKEEINKPPVAKITGNVVVTLPTSTVELDGSRSSDDKGIVSYLWTRDEASPAAGEVLNHSDHHPVLFLSNLVEGSYTFHLKVTDAKGESDTDRTTVEVKPDPRKSNLVEIILDVNVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMLFFVQNDPPHQFFKGREVAAMLKSELRKQKADFLIFRALEINTVTCQLNCSDHGHCDSFTKRCVCDPFWMENFIKVQLRDGDSNCEWSVLYVIIASFVIVVALGILSWTTVCCCKRQDGKPKRKSRYKILDATDQESLELKPTSRAGSKQKGPTMSSSLMHSESELDSDD--AIFTWPDREKGKLLHGQNGSVPNGQTPLKTRSPREEIL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K135-1", "uniprot_id": "K319L_MOUSE", "id": "Q8K135-1", "name": "Dyslexia-associated protein KIAA0319-like protein", "aln": "-----------------------------------------------------------------------------MEKRLGVKPSPASWVLPGYCWQTSVKLPRSLYLLYSFFCFSVLWLSTDADESRCQQGKTLYGAGLRTEGENHLRLLAGSLPFHACRAACCRDS-----ACHALWWLEGMCFQADCSKPQSCQPFRTDSSNSMLIIFQKSQTTDDLGLLPEDDEPHLLRLGWGRTSWRRQSLLGAPLTLSVPSSHHQSLLRDRQKRD-LSVVPTHGAMQHSKVNHSEEAGALSP-TSAEVRKTITVAGSFTSNHTTQTPEWPKNVSIHPEPSEHSSPVSG----TPQVKSTEHSPTDAPLPVAPSYSYATPTPQASSQSTSAPHPVVK--ELVVSAGKSVQITLPKNEVQLNAFVLP-EAEPGETYTYDWQLITHPT-DYSGEVERKHSQSLQLSKLTPGLYEFKVTVDGQN-AHGEGYVNVTVKPEPRKNRPPVAVVSPQFQEISLPTTSTIIDGSQSTDDDKIVQYHWEELKGPLREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTASLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPALQLSAMQEGDYTYQLTVTDTAGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSTDDQRVVSYLWEQSRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIAGNVVVTLPTSTAELDGSRSSDDKGIVSYLWTRDETSPAAGEVLNHSDHHPVLFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKSNLVEIILDVNVSQLTERLKGMLIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMLFFVQNDPPHQLFKGHEVAAMLKSELQKQKADFLIFRALEISTVTCQLNCSDHGHCDSFTKRCVCDPFWMENFIKVQLRDGDSNCEWSVLYVIIASFVIVVALGILSWTTICCCKRQKGKPKRKSRYKILDATDQESLELKPTSRAGSKQKGPTLSSSLMHSESELDSDD--AIFTWPDREKGKLLYGQNGSVPNGQTPLKSRSAREEIL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZA0-1", "uniprot_id": "K319L_HUMAN", "id": "Q8IZA0-1", "name": "Dyslexia-associated protein KIAA0319-like protein", "aln": "-----------------------------------------------------------------------------MEKRLGVKPNPASWILSGYYWQTSAKWLRSLYLFYTCFCFSVLWLSTDASESRCQQGKTQFGVGLRSGGENHLWLLEGTPSLQSCWAACCQDS-----ACHVFWWLEGMCIQADCSRPQSCRAFRTHSSNSMLVFLKKFQTADDLGFLPEDDVPHLLGLGWNWASWR-QSPPRAALRPAVSSSDQQSLIRKLQKRGSPSDVVTPIVTQHSKVNDSNELGGLTTSGSAEVHKAITISSPLTTDLTAELSGGPKNVSVQPEISEGLATTPS----TQQVKSSEKTQIAVPQPVAPSYSYATPTPQASFQSTSAPYPVIK--ELVVSAGESVQITLPKNEVQLNAYVLQ-EPPKGETYTYDWQLITHPR-DYSGEMEGKHSQILKLSKLTPGLYEFKVIVEGQN-AHGEGYVNVTVKPEPRKNRPPIAIVSPQFQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGPLREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDINVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSELRKQKADFLIFRALEVNTVTCQLNCSDHGHCDSFTKRCICDPFWMENFIKVQLRDGDSNCEWSVLYVIIATFVIVVALGILSWTVICCCKRQKGKPKRKSKYKILDATDQESLELKPTSRAGIKQKGLLLSSSLMHSESELDSDD--AIFTWPDREKGKLLHGQNGSVPNGQTPLKARSPREEIL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA74-1", "uniprot_id": "A0AB32TA74_DANRE", "id": "A0AB32TA74-1", "name": "", "aln": "------------------------------------------------------------------------------------MPN-VELRMHRWKWQTRFT---SLYLS----CVYLLCSVSGVSGSICSVTGGVLGIHWSSVIGLGWQPLAVDQGGSRCWESCCLEP-----SCGAVWSLGGRCVLLACSQRETCG----------------------ISSLP---------------------------QPHVESLGLLQLLNKSKRRKTRSAQDIRAIRDTEQDMSSNPSEPLTTSNSAAS-------SSSSGEQTAEH-----NTTLDSDAANHSTLNNS----NQSPQST----------VAP---------------ATTPAVTVR--ELVVSAGQNVEVTLPRNEVKLSAYVVP-APPTGTNYDFDWRLITHPK-DYSGEMEGKHTMTLKLSKLTVGLYEFEVVVDGEG-AHGEGYVNVTVKPEPRVNKPPVAVVSPKYQEISLPTSSTVIDGSRSTDDDKVVLWHWEEVKGPLREEKASGDTDILTLTNLVPGNYTFSLTVTDSDGAQNSTQAMLLVNKATDYRPTANAGPNQVITLPHNYITLNGNQSTDDHDNLSYEWSLSPESKGKVVEMQGVRTPTLQLSAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAGPDKELTLPVDHTTLDGGKSTDDQKIVTYHWKKTKGPEGVKLDNAETVVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIVREENDQPPVAKVVSSPPITLPVRTAVLDGSRSSDDKGSISYLWTREENSPAAGDVLNHSDHQAVLFLGNLVEGKYSFTLTVTDSKGKTSSDSGVVDVRPDVYERDLVELILEVAVAQVSRRQKDMYIRQVGVLLGVLDSDITIREISAFNEHSTRLVFLVSGGPGRPPLTGHSVAMELRNKFRKQKNEFLIFKARRVDTVICQLNCSGHGECDSFTRRCVCHLFWMENLFSTYFGDAESNCEWSVLYVTIASFMIVVAIATVIWGLVCCCRRRKSKVRRKSRYKMLNEDDQETMELKLPRPGRLKSVPAPTSSALMHSDSDLESDDGQAGIPWSDRERGKLLPPQNGSLRNGQGPHKPKKTREELL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSC9-1", "uniprot_id": "Q9VSC9_DROME", "id": "Q9VSC9-1", "name": "MANSC domain-containing protein", "aln": "-----------------------------------------------------------MVQVGKRICNLLLLATAMSSAYADVTTQNALLVGSKKHKETSPDNSVGGSISPNLVCHKMLRHVFENATPRDEQQAGVFEEYKPP--PDAVEPLEEEAYLWNCLQACCEKPRNGSSACNVVLVFKAKCYHIRCQSNEACLP--------KLRVRMPNEKVQMVLVNPLGDATWPQLLKAEAAKQNAEILPYDEAALNFWKQPRRLSYLARNQETPVYEDEDFPLADKRMNQMIFQPDENDVLANEELGYYDSNAKFTTCDMETPCPPPQQCVPLQPNAVRGVCTCPEGFVWNKQRKCVMAAVPYSSYLTSNEAGQQEAAASENSPEVSTPPLKAEQNKDIVVSVMSKEVRLPEQEVTLAAFTVPDEQTSDTKYKYLWTLISQPKGPMNGTISDQSKSKVKLSNLSEGLYTFKVTVTGDNGTFGEATANVTVLPENRINQPPQVIISPREQIIRQPTTNAILDGSTSTDDDKITNWHWEVISGPIGYQPVLPEVNTLQLDLTSPGNYTFKLTVTDSNNVTNSTTATIAVLKETDYAPVANAGDAVILYLPNNNVTLNGTASSDDHEIVAWEWTKDASDEAKAVDMQNTRTPYVQLSNLEEGMYTFVLKVTDGSGQSSTAKVHVFVKPPTNSPPVAEAGSNTTTSLPINWVLLNGSDSKDDIGIKSYLWKQLSGPNNAVILKSNSSIANATSLTLGLYEFELTVADENNNTATDTTWVKIVQERNAAPIANAGGDHTVTLPATAIYFNGSKSWDDLAVVKYLWTRDEHSLAAGVIVADTDKEPVMILTNLVQGRYVFTLTVSDDQGLTSSDTVSVNVRRDPKLLNLVQMTLPMGISVLVQSELDSVVQKLQLLLGDENKIQVRELKYDLHTDATVLVFYVNDGQGK-ALDGLQVERQLRTQLQKDAS-ILGAFAVDIRTSVCQSDCSGHGSCNPITRACICEAFWMP-SAGYFFNNQEANCDWSILYVFVGVIVGCLLLSGVFWGIACACRQSK-KPRLRQKVQKYSLIGNKDEEAANYSRNTSLTESETDSDVLFETRTKSNGLG--KHKSHNSHSHGHGSSGGSGSSGRDGHKYGTQKLGRKIKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : . : * :* . . * * :** .. :* .. : . * *. ::* : * . . ::. : . : : : ..: .: . . :. .: .::* . : :* : . :: **.:** * *:.: . .* : * **::* .* :. : . ::**:*: *** *:* * *:. :.**. .**** ** * *:** .::**: * * **:.:::*** ******:. :*** :.**: : :. * * ******.***.**:.. *** * : * * .** *.**** :: **:* :** *. *:*** ::**: ....:.*.*:**..*** :*** ::** **: *.*** **. *::* *:*:* .*.** *:**.:. :**:: . *:*..*.** : :* *:: **:.. : :::: :*..*.* * * * *** **.* : .:. * : :* : .*:*: .. :***. : ::**:* ** . :.*****:* * *** :: .:*:..:::* ***:* * * *.*:* :* :.:* *:*: * :**:: * : :: : . . :::: :*** :. . .:* ::* *.. : : * .* *:.:::*: :* * : * ** :**.** *:.:*: *:*. *** : : ::**:**:*** :. :: : :. : * *.*:: . * : :.: : . .:: * *. *:.: :. :. . . .:.:*: .** .. .:. .:: ", "identical_positions": 243, "similar_positions": 299, "identity": "21.24%" }, { "cls_id": "homologset.agr.MGI:2140494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3G1-1", "uniprot_id": "PP1R8_MOUSE", "id": "Q8R3G1-1", "name": "Nuclear inhibitor of protein phosphatase 1", "aln": "MAAAVNSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRMEGSGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSETGSQPHGIHG--TALIGGLPMPYPNLAPDVDLTP-VVPSAVAINPTPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNL5-1", "uniprot_id": "A0ABZ3NNL5_RAT", "id": "A0ABZ3NNL5-1", "name": "Nuclear inhibitor of protein phosphatase 1", "aln": "MAAAVNSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPEDVDPSVGRFRNMVQTAVVPVKK-RMEGSGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEPGSQPHGIHG--TALIGGLPMPYPNLAPDVDLTP-VVPSAVTINPTPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12972-1", "uniprot_id": "PP1R8_HUMAN", "id": "Q12972-1", "name": "Nuclear inhibitor of protein phosphatase 1", "aln": "MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHG--TALIGGLPMPYPNLAPDVDLTP-VVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF58-1", "uniprot_id": "A5PF58_DANRE", "id": "A5PF58-1", "name": "Nuclear inhibitor of protein phosphatase 1", "aln": "MAAIASTNTTG--FDCPSWAGKPPPGLHLDVVKGDKLIEKLIIDEKKFYLFGRNPDHCDFTIDHQSCSRVHAALVYHRHLKRVFLIDLNSTHGTFLGRIRLEPHKPQQVPIDSTMSFGASTRVYTLREKPQTQSSSTTGDSK-GVEDEELKGLLGLPEEETELENLTEFNTAHNKRISTLTIEEGNLEIQRPKRKRKSSRVSFSEDEEIINPEDVDPSVGRFRNMVQTAVVPIKKKKLEGHSTLGLDENVARRLQNFPLSGGLYGDLPPTSHEAGGQGGGGQGGGSAITGGMPLPFPNPAPEVDVSPTTVQPPAMLNPTPAPGPYSAEPLNEPRKKKYAKEAWPGKKPTPSLLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ..:.:: ****:*****************************:******** ********************:*******************:**********:*****:*******.********* .*:..**.* * **:***************:***********************:*********.***:**:*:*************************:** ::** .:***:*. :**:***.:******.**** *.*.* * :* :*: **:*:*:** **:**::* .* ... :**:* *. *..*.:***:********************", "identical_positions": 269, "similar_positions": 60, "identity": "75.99%" }, { "cls_id": "homologset.agr.MGI:2140500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNK8-1", "uniprot_id": "TET5B_RAT", "id": "B0BNK8-1", "name": "Terminal nucleotidyltransferase 5B", "aln": "--------------------------------------------------------------------------------------------------------------------MMPSESGD-------------ESLEQ-----------------------------------PAAQVGTGAASAVATAG-----------------------------------------------------------AAGGG-----------------------------------PDLEASSASLG------------------------------------RHQSR------------------------------------------------------LSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEQ------GLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFQMDLQSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCT--DLDRWSLISLSNKSG-KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDPVEQRRILERYLEAHFGGA-EAARRYACLVTLHRVVNESTVCLMSHERRQTLDLITMLALQALAE--------------------------------------------------------------------QGP------------AAMAALAWRRPG--SDGVVPATVNYYVTPMQPLLPRAHSYPTWLP-----CN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C152-1", "uniprot_id": "TET5B_MOUSE", "id": "Q8C152-1", "name": "Terminal nucleotidyltransferase 5B", "aln": "--------------------------------------------------------------------------------------------------------------------MMPSESGA-------------ESLEQ-----------------------------------PAAQVGTGAASAVATAG-----------------------------------------------------------AAGGG-----------------------------------PDPEASSASLG------------------------------------RHQSR------------------------------------------------------LSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEH------GLRVHSVRLHGSAASHVLHPESGLGYKDLDLVFQMDLRSEVSFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCT--DLDRWSLISLSNKSG-KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDLVEQRRILERYLEAHFGGA-EAARRYACLVTLHQVVNESTVCLMSHERRQTLDLIAMLALQALAE--------------------------------------------------------------------QGP------------AAMAALAWRRPG--SDGVVPATVNYYVTPMQPLLPRAHSYPTWLP-----CN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A09-1", "uniprot_id": "TET5B_HUMAN", "id": "Q96A09-1", "name": "Terminal nucleotidyltransferase 5B", "aln": "--------------------------------------------------------------------------------------------------------------------MMPSESGA-------------ERRDR-----------------------------------AAAQVGTAAATAVATAA-----------------------------------------------------------PAGGG-----------------------------------PDPEALSAFPG------------------------------------RHLSG------------------------------------------------------LSWPQVKRLDALLSEPIPIHGRGNFPTLSVQPRQIVQVVRSTLEEQ------GLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFRVDLRSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCT--DSDRWSLISLSNKSG-KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFTEALEHLRHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDLVEQRRTLERYLEAHFGGA-DAARRYACLVTLHRVVNESTVCLMNHERRQTLDLIAALALQALAE--------------------------------------------------------------------QGP------------AATAALAWRPPG--TDGVVPATVNYYVTPVQPLL--AHAYPTWLP-----CN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4P7VA97-1", "uniprot_id": "A0A4P7VA97_DROME", "id": "A0A4P7VA97-1", "name": "polynucleotide adenylyltransferase", "aln": "MVNKKADKDKERQQEAMLPAAGKNSSNIENSSKLSNNNNYNNNKTNKGQSTKPNSNNNSGNNKKNAGKGNQQQSQRSGKKAKPQRQQIFLQSLPRDSSNYRSNSFRNSIDINSNSSNMSSKSSSNMSSNSSNISDTLATLDSGVGKINPAELLTAALAVPCAKCSKPSMISGLTTAVTASTVPASASSSSASASSFSSSSTSSGSETASNHSDLHYPEPVVYSAKQYRKSKSYMGVSQYNSSQNGHQAGRAPNTAGGGNGNHVAYRRSHSDRRNSFDRSFAERNRDFVPIVPPPRPVLSSSNIAGVMASTTKLTIIERLGKGRLAYPIMQCGTLDGAEPLYHQQRSNRMDVYQIDDGFHSDGGTETPPPSPSSGSSIASTSDHGSLESVDTGGTQRLAVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLASEDQP-YNDLDLIFAIELSSPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSPGHKNVELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDCAALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQVLFNKQEKQQQQQAQEKYQQQQQQQQHQQNQQQQQQQRQHQFLDPAQQQQQQQQTQTQQQQAQQATTLTLVPQAPPTGQAQTIYVQQAAPAAVCCTSSADQTATAAPQTIQIQAGPPGLIYANGVYYAPVIPSTICTCNSTWLSTXLERQEQEKEQQHHQHEQQQFQQQQWSEDALGATLLAETETEPPLATASIAPPPPSSQPPSSPSTTAPRTQVQNQTRSTTINSSNRKKKNKAKTQSKQQTQTATEAESNCNEKPTTATMTRTTTKKSSRIKQMAAAAAATEACAAKGGAGGITGSLVLTPQQINGLPVYNQLDDGGRSAAGTYSGQFAYFYPHDGSAPSMFLLGEDSYLNVTEQQEQHQHQHQHHNHQFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*:*. : .*: * :.*::: *:*. .**** * *: . * . **: **.:*. ::.* :.**********.*: :::*::** .** . *: *:.:**:*.****** .*. *:****:* ::* * *: .*..** ***::* **.: :* . :****** *:*** . * ********.*..* *********::*******:*****:******* :*:: *:** *:***.***:**** *** **::::*:**.*************:****.::. * :::*:************* * ** **. ** *. : . :* *: *:.**: ******.*****:*.** ** *.* : *.* ** **:. .. : ..* *:: . * : . *.. :* ** ", "identical_positions": 216, "similar_positions": 119, "identity": "19.49%" }, { "cls_id": "homologset.agr.MGI:2140592", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6X893-1", "uniprot_id": "CTL1_MOUSE", "id": "Q6X893-1", "name": "Choline transporter-like protein 1", "aln": "--------MGCCSSAS-AAQSSKREWKPLEDRSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQR-NAKLEAIPNSGLDHTHRKYVFFLDPCNLDLINRKIKSIALCVAACPRQELKTLSDVQKFAEINGSALCSYNIKPSEYTLTSKSSG------FCPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKQRRSPKEAVIPEQLQIAEDN---------LRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFLGTTGSA-------------------------------VQNE-QGFVEYKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFT-RDKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMVLMYIHSQLK---GKENACARCMLKSCICCLWCLEKCLSYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQ-QDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYN--DGSPGREFYMDKVLMEFVENSRKAMKEAGKGGAADAR--------ELKPMLRKR------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VII6-1", "uniprot_id": "CTL1_RAT", "id": "Q8VII6-1", "name": "Choline transporter-like protein 1", "aln": "--------MGCCSSAS-AAQSSKREWKPLEDRSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQR-NAKLEAIANSGLDHTHRKYVFFLDPCNLDLINRKIKSMALCVAACPRQELKTLSDVQKFAEINGSALCSYNIKPSEYTLTAKSSA------FCPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVIPEQLQIAEDN---------LRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFLGTTGSA-------------------------------VQNE-QGFVEYKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFT-RDKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLK---GKENACARCMLKSCICCLWCLEKCLSYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQ-QDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYN--DGSPGREFYMDKVLMEFVENSRKAMKEAGKGGAADAR--------KLKPMASGASSA---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WWI5-1", "uniprot_id": "CTL1_HUMAN", "id": "Q8WWI5-1", "name": "Choline transporter-like protein 1", "aln": "--------MGCCSSASSAAQSSKREWKPLEDRSCTDIPWLLLFILFCIGMGFICGFSIATGAAARLVSGYDSYGNICGQK-NTKLEAIPNSGMDHTQRKYVFFLDPCNLDLINRKIKSVALCVAACPRQELKTLSDVQKFAEINGSALCSYNLKPSEYTTSPKSSV------LCPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVTPEQLQIAEDN---------LRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWVYWIMTLLFLGTTGSP-------------------------------VQNE-QGFVEFKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFT-RDKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLK---GKENACARCVLKSCICCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQ-QDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYN--DGSPGREFYMDKVLMEFVENSRKAMKEAGKGGVADSR--------ELKPMASGASSA---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QGI9-1", "uniprot_id": "A0A8M9QGI9_DANRE", "id": "A0A8M9QGI9-1", "name": "Choline transporter-like protein", "aln": "MSEVRRSGSGSYRPRSSWIKRTKREWKPLEDRSCTDLPWFLLFTLFLVGMCGICGFTIATGGAARLVFGYDSYGNTCGQR-NEPIEGVRLSGLDHTDRKFVFFLDPCNIDIIQRKIKSMALCVSQCPTEELLTYYDLKRFAMMNGSELCSYELPGHKYPSLPERFD------KCPKLPVPESKALPVFNRCTPVDISCYAKFAEAVVTFVSDNSMLNRLIAGVAASKEIIVGLCLLALVLSMILMVIIRYISAVLVWILTALVVLGSLGGTSVLWWLYIDYRMTMNETMTKDLTETEEPNGGMKPTKDHAQGLLIYAVSATVFTGILLLLMLFMRKRVALTIALFHVAGKVFIHLPLLALQPFCTFLALSLFWVYWIMVLLFLGTTGNP-------------------------------EKNEDTGLVEFRLSGALQYMTWYHAVGLIWISEFILACQQMTVAGAVVTYYFT-RDKTKLPVTPILSSVLRLVRYHLGTVAKGSFIITLVKIPRLILMYIHNQLK---GKENACARCMLKACICCLWCLEKCLNYLNQNAYAATAINSTSFCTSARDAFMILVENALRVATINTVGDFVLFLGKVLIVTCTAFAGVLALNYQ-RDYTEWVLPLIIVCLFAFLVAHCFLSIFEIVVDVLFLCFAIDTKYN--NGTPGREFYMDKALMEFVENSRRSMAMEERGRSKRARPKEEVELTEVKAMVSGDGGSAGAEWQALQEFHLYYLLLCVLMDWALTEHTLVLCLTQDMIIFLSVCLPTSTLFFLVTLLQSPPVAAAAC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q9M4-1", "uniprot_id": "F1Q9M4_DANRE", "id": "F1Q9M4-1", "name": "Choline transporter-like protein", "aln": "--------MGCCGSTQ-----KERDWKPLEQRRCTDIPWLLLFILFNIGMLCICGFAIATGAATRLVSGYDSYGNTCGQK-NAQIPGIEHSGLDHSNRKYVFFLDPCKIDIAKRKIKSVALCVSKCPKVQLDTYEDLTKFATVNGSALCTYDVQPEAYSSNPNKDV------KCPKLPVFPSASLPVFHRCMPVDISCFATFAKAFITFVSDNSVLHRVIAGVMMAKEIIMGLCLLALVLSLILMVVIRYISVLLVWILTAVVVIGSVGGCGILWWLYVDQGKALNATMPAHDLEIAHDN---------QQALLIYAIGATIFTVLLLLLMFFMRKRVALTIALFHVAGKVFTHLPLLALQPFWTFLTLMLFWVYWISVLLCLGTAGSP-------------------------------VKNNRTGLVEFKMDGPLQYMVWYHAVGLIWVSEFILACQQMTIAGAVVTYYFT-RDKSQLPFTPIVSSVLRLMRFHLGTVAKGAFIITLVEIPRLILTYIHSQLK---GKENACARCMLKACICCLWCLEKCLSYLNMNAYTATAINSTNFCTSARDALFILAENALRVAAINSVGDFVLFLGKILIVSCTAFAGVLSLNYQ-REYSVWVLPLIIVCVFAFLVAHCFLSVFEIVVDVLFLCFAIDTKQN--DGSPGREYYMDKSLMEFVENSRKATEKYSKAE-GDSR--------EMKSMTGGTLA----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZE7-1", "uniprot_id": "CTL1L_DROME", "id": "Q9VZE7-1", "name": "Choline transporter-like 1", "aln": "--------MGCAESKD---GEGEAQNNRPKYRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFD------VKELKKSLKICVKSCPAKTMTKGSELLEYYSQTGTQLCKYDYNMQQLTTAGNDAKTFNFLGPCPSFPVHESS--PVLHRCVPKGT---GEKVQNYYDMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIRNKSGVNTQYSMLEEFVRN---------QQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFWYFQ-KPTS----TPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAALSGLIGIVLLKDK-PGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSGRWAQSNLAKLVGEEPLQPGEEPPIEVVQMMPINKQPFSITRLPQSDPEVAPMSAD---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12412-1", "uniprot_id": "PNS1_YEAST", "id": "Q12412-1", "name": "Protein PNS1", "aln": "-----------------------------------------------------MPLNEKYERPPQPPPAYDPNHRPPSSSENSAAANVNDGQTPYHFRQDQYYNLNSKTSGAPIGSFDEAFPTENDNKPRWNDWPFTIFFLCTVGGFIAIAAITLRAWSQTYSSTG-------------------------------------SGIYDGVNTGTLN-------TNAAILLVFVCIIALVFSVLGLTLCRIFPKQFIYCGMVINLVASLG--TAIMYMSLRYWSAG--------------------------------IVFLVFTFMTAWCYWGMRSRIPLSVAVLKVVVDAMKKCPQIFFVSFVGALVASAFGFLFSAVIVATYIKYDP-----------------------------NSSNGGCDVSGGSCSHSKLIGVLVVVFFCGYYISEVIRNVIHCVISGVFGSWYYMSKSDQGMPRWPAFGALKRAMTYSFGSICFGSLLVALIDLLRQILQMIRHDVTSS-GGGQIAIQILFMVFDWIIGFLKWLAEYFNHYAYSFIALYGKPYLRAAKETWYMLREKGMDALINDNLINIALGLFSMFASYMTALFTFLYLRFTSPQYNSNGAYNGALMAFSFVIALQICNIATEAIRSGTATFFVALGND-------PEVFHHSYPHRFDEIFRAYPDVLRKLSHQNV------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .**. . . * . . : :: . : . : * :. . . . :. : : :: :* ::*::*: :.: : :. . : : ::.*:. : : : : : ::.::. *::. . . : : * : : .: :. * : .:: .. . . * : . : *.* : .::... :*: : * . :: : : : :*::. *::::::..: * :* : .:. . . . : : *: ::* **: *: . : :* : : : : . :.: :: * * .:. :.: .: *. . : *:*.:* : .: .: . : . . . : . : ", "identical_positions": 32, "similar_positions": 167, "identity": "4.02%" }, { "cls_id": "homologset.agr.MGI:2140623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BJG4-1", "uniprot_id": "MOB3C_MOUSE", "id": "Q8BJG4-1", "name": "MOB kinase activator 3C", "aln": "------------------------------------------------------------------------------------------------MALC-LKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGESIDDWIAVHVVDFFNRINLIYGTMAEHCSESSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEDVFPTRVGVPFPKNFQQ-VCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIQEFSLVDQRELEPLREMTERICH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP72-1", "uniprot_id": "D3ZP72_RAT", "id": "D3ZP72-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MALC-LKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRRVVRLPPGESIDDWIAVHVVDFFNRINLIYGTMAEHCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEDVFPTRVGVPFPKNFQQ-VCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIQEFSLVDQRELEPLREMTERICH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70IA8-1", "uniprot_id": "MOB3C_HUMAN", "id": "Q70IA8-1", "name": "MOB kinase activator 3C", "aln": "------------------------------------------------------------------------------------------------MALC-LKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQ-VCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL13-1", "uniprot_id": "MOB3_DROME", "id": "Q9VL13-1", "name": "MOB kinase activator-like 3", "aln": "------------------------------------------------------------------------------------------------MALNGFLEFFQKGKTFRPKKPFASGTIRYSLHKQAQASLQSGINLRQVVRLPQGENLNDWLAVHVVDFFNRINLIYGTVSEFCNETTCPTMSGGSRYEYLWADGDLYKKPTALSAQKYIEHLMDWIETQINNEAVFPVSTDVPFPKNFIA-ISRKILTRLFRVFVHVYIHHFDRIVSIGAEAHVNACYKHFYYFVQEFDMISAKELEPLQEMTSRICKDKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40484-1", "uniprot_id": "MOB1_YEAST", "id": "P40484-1", "name": "DBF2 kinase activator protein MOB1", "aln": "MSFLQNFHISPGQTIRSTRGFKWNTANAANNAGSVSPTKATPHNNTINGNNNNANTINNRADFTNNPVNGYNESDHGRMSPVLTTPKRHAPPPEQLQNVTDFNYTPSHQKPFLQPQAGTTVTTHQDIKQIVEMTLGSEGVLNQAVKLPRGEDENEWLAVHCVDFYNQINMLYGSITEFCSPQTCPRMIATNEYEYLWAFQK-GQPPVSVSAPKYVECLMRWCQDQFDDESLFPSKVTGTFPEGFIQRVIQPILRRLFRVYAHIYCHHFNEILELNLQTVLNTSFRHFCLFAQEFELLRPADFGPLLELVMELRDR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *.* : . * : .: : .: :* * *. .*:** **. ::*:*** ***:*:**::**:::* *. :** * . .*** * : *. :** :*: ** * : :::* :** . .**:.* : ** *****:.*:* ***: *:.:. :: :*:.::** * :**.:: :: ** *:. .: . ", "identical_positions": 67, "similar_positions": 72, "identity": "21.14%" }, { "cls_id": "homologset.agr.MGI:2140651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B5N9-1", "uniprot_id": "A0A8I6B5N9_RAT", "id": "A0A8I6B5N9-1", "name": "", "aln": "MAARAPPAAPAADEPGSPGGPPRRKKSRSGLRRAFSWLRGKRRKKKAAGAEGAESAAPRAKKAEDKAKRSKGKSRGSAKAESDNRQGAGPSQGPGSVGDEHQDNVFFPSGRPPHLEELHTQAQEGLRSLQQQERQKLSKGGWDHGDTQSIQSSRMGPDEDTISFCSQK-SYMTESSTAEDALSIRSEMIQRRGSTFRPHDSFPKSGRSGRRRRERRSTVLGLPQHVQKELGLRN-----NREAPGTPQPPGSRDAVRIPTVDGRPAGLALGTGVRVSLQALEAEAEAGTDTEAIIQRHIDRVYRDDTLVGRSTGARPPPLTRPVSLAVPGLTGGAGSPEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRSSLRTLSRCSLLSASPASVRSLGRFSSASSPRPRSRNASSSSDNWSHSQSSETIVSDGSTLSSKGGSEGQPEGSVASNSVVPPPP-----------GGSGRGSPSGGSTAEVSDTASIRSSGQLSGRSVSLRKMKRPPPPPRRTYSLHQRGSAVP------DGPLGLPPKPERKQQPQLPRPPTTGGSSG----------------VGAVSCPPSSGGTWGSGLSPGGSRRPPRS------PERTLSPSSGYSSQSGTPTLPPKGLAVAPASPGKAQPPKPDRVTSLRSPGASVSSSLTSLCSSSSDPTPLDRSG-----------------------PQASNPLSDRFVIPPHPKVPAPFSPPPSKSKSSNQAAPALAAP------------------------AVVPGPVSTADISPA---------------------------------------------------------------------------------SPSMPQTTLTPAQESPIASKDQ-----------------------------SPPPSPPPSYHPPPPPTKKPEVLEEVPPPPE-------TVEILPDPSWPPPPPPAPEEQDLSMA-----DFPPPEEVFFSAG-------------------------PELG--PLEPCSSEAAIPSAASL---------------------------------------------------SQTPPPAPPVPPPASSVSEPLAKLPQKDSASC--------KNSGTPREDAGTPLVTPSLLQMVRLRSVGASTGAPNPPPGSS---------------APQKPLRRALSGRASPVPAASSG--------LHAAVRLKASSLAAS-------ESPGNALPTGAPETEPRSPQ------SPASKASFIFSKGTKKLQLERPVSPEAQADLQRNLVAELRSISEQRPS---QTQKKPSKAPPPVARKPSVGVP--LSPSLPRAESLDAPSTNGLPHAEDRTKGELTENGGVQLAAT--EKMGPHGSDPQKKLV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A7S8-1", "uniprot_id": "NHSL3_MOUSE", "id": "A2A7S8-1", "name": "NHS-like protein 3", "aln": "MVVFLGRHLPALLEVFK---------------------------------------------------------KGSAKAESDNRQGAGPSQGPGSVGDELQDNVFFPSGRPPHLEELHTQAQEGLRSLQHQERQKLSKGGWDHGDTQSIQSSQTGPDEDTISIYSQK-SYMTESSTAEDALSVRSEMIQRRGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRN-----NREAPGTPQPPGSRDAVRIPTVDGRP-GLALGTGVRVSLQALEAETEAGTDAEAVIQRHIDRVYHDDTLVGRSTGARPPPLTRPMSLAVPGLTGGAGSPEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRSSLRTLSRCSLLSASPASVRSLGRFSSASSPRPRSRNASSSSDNWSHSQSSETIVSDGSTLSSKGGSEGQPEGSVASNNVAPPPP-----------GGSGRGSPSGGSTAETSDTASIRSSGQLSGRSVSLRKMKRPPPPPRRTYSLHQRGSAVP------DGPLGLPPKPERKQQPQLPRPPTAGGSSG----------------VGAVSCPPSSAGTWGSGLSPGGSRRPPRS------PERTLSPSSGYSSQSGTPTLPPKGLAVAPASPGKAQPPKPDRVTSLRSPGASVSSSLTSLCSSSSDPTPLDRSG-----------------------PQMSTPLSDRFVIPPHPKVPAPFSPPPSKSKSSNQAAPVLAAP------------------------AVAPGQVSTIDTSPA---------------------------------------------------------------------------------SPSMPQTTLTPAQESPVASKDE-----------------------------SPPPSPPPSYHPPPPPTKKPEVLEEAPPPPEA------AVEILPDPSWPPPPPPAPEEQDLSMA-----DFPPPEEVFFNAG-------------------------PELG--PLESCSSEAAVPPAASL---------------------------------------------------SQTPPPAP----PPSSGSEPLARLPQKDSVG---------KHSGAPREDSGTPLVTPSLLQMVRLRSVGASTGIPNPSPGSS---------------APQKPLRRALSGRASPVTAPSSG--------LHAAVRLKASSLAAS-------ESPASALPTGIPEAEPRSPQ------SPASKASFIFSKGTKKLQLERPVSPEAQADLQRNLVAELRSISEHRPPP--QAQKKPSKAPPPVARKPSVGVPP-PSPSLPRTESLTAPSTNGLPHAEDRTNGELAENGGVQLAAT--EKMGSPGSDPQKKLV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P206-1", "uniprot_id": "NHSL3_HUMAN", "id": "Q9P206-1", "name": "NHS-like protein 3", "aln": "MVVFVGRRLPALLGLFK--------------------------------------------------------KKGSAKAENDKHLSVGPGQGPGSAVDEHQDNVFFPSGRPPHLEELHTQAQEGLRSLQHQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISFCSQTTSYVAESSTAEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRN-----EREAPGTPRAPGARDAVRIPTVDGRPRGTSG-MGARVSLQALEAEAEAGAETEAMLQRHIDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ-----------GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVP------DGPLGLPPKPERKQQPQLPRPPTTGGSEG----------------AGAAPCPPNPANSWVPGLSPGGSRRPPRS------PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSG-----------------------PQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAP------------------------AVVPGPVSTTDASPQ---------------------------------------------------------------------------------SPPTPQTTLTPLQESPVISKDQ-----------------------------SPPPSPPPSYHPPPPPTKKPEVVVEAPSASET------AEEPLQDPNWPPPPPPAPEEQDLSMA-----DFPPPEEAFFSVASPEP---------------AGPSGSPELVSSPAASSSSATALQIQPPG---------------------------------------------------SPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCS-------KGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPS---------------APQKPLRRALSGRASPVPAPSSG--------LHAAVRLKACSLAAS-------EGLSSAQPNGPPEAEPRPPQ------SPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPP---QAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQKELA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWM5-1", "uniprot_id": "NHSL3_DANRE", "id": "Q1LWM5-1", "name": "NHS-like protein 3", "aln": "MVVFLSKNVRSLLSIFK---------------------------------------------------------KKGQKQDEQRKLTVHYTAS-----QHYQENVFIEGSRPKYLEDLHTEAQEGLKILQQEEEDTSSKERNESLENDSTSG------------------HSIISVSTASAVSTR-PVLTRQGSTFKPLNPVKRLDKS--KRRSRRTTIMGIPQQVQRELDMARGTMLQQLPNRGHDSEDDSSGTVVLQTIDGDLPSVNH-EGARVHLQNIEVLQAS--RDEDLLLNHIHSVYQDELNR--KLGLGACPTQRPKSLAVPGMTTYSFLQEPQGPVMSISPQATYLSKIIPNAVLPAAIDIIEIN----HDHNRCSASTASKGSMASASPSSSRSGSGTN-QAPPTTSPSRSNSQSSETIVSNSSTISSKGKCLPTFDADSAKDISVLIPKDMSVSSSSSWKSSEGKGTNHRLNPREYGDAGDNVRNSHSFSRSLSVMKTKLPPAPPQRTYSLHHENMQRQREQGDIQDPKDVAPNNNEQTNRDISSTKENHQSAKNKKSSVHSLELRSDFHTTVKSSPLSPDQVFTGRHARSGNSSPQKTRECGENFDRTLSPSSGYSSQSGTPTHSPKEVSPSSPGKRRVKPSKPERVCAKTSPVVSVSSSLTSLSSVISDTAHQDIQTNTTSSEPLKFSPPLTTVKNKVTPTHQTIALRTLFNIPPPPKVKAPSPPPPETWVQNKQTLELLCGPGPNIHKLESLISKTQNKNSMQINEQVIPKTQTTEETKTENTVVKELTKSASPQVHKQMMVEPPDVRHTEKSILHNELKSPETLAKVNQIPHTQDEKTIEDQKDRWSQTLPTTNVPSIIVDQSMLSQTNSIEKTKAATVSSNENQRNCIVTDIVNRISVQTLNIEVPEVNGVSPPPSPPPEHHPPPPPIKKMSDMSVSIPPSEKEEQKQVEQVTFPESSWPPPPPPMEESTELMFEEQDELDFPPPPPSFIHEPMSEISDDFHEESCEEVSIKLLSTNVSDMDSSPEQDSERHTILPKRIVQNSVEVRQQDKSSDSVSEFLEDQAEIENTNVASTIISSHLPDKNLHEKETLVSTSIPLAPPLPVEEQSTINFRKQLSFVDKDNRSKELLCRHKSTPIPKEDANIPLVTPSLLQMVRLRSVNVGEDQVNNDSKPSTEPTTNEDHSISSQVTPQKPIRRSLTLKSNSPAKSSSASSAVPSMCLQEAIRMKTAAMSCSGVPAMLNLRSSSGSSATSPVPSPKSPDGCDLLMSPASTASFIFSKSTKRVVIETPTSPDVQASLKQSLAAEIMQVSDQAKTMITNGTKKPIKVPPPVAKKPVHGSNPPNKMENATQDKTEILTNKQIMRVDVNGQSDQVHPAGQRAQSLGNQEQASKEAFAMNMSICA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. : . : . * :.:.: . . :. *:***: ..** :**:***:*****: **::*.:. .* : :.:* .. : * :: .*:* * :: *:****:* :.. : .:* :**.**:*::*:**:**:**.: . : * .: .:* : *:** . *.** ** :*. : * :: .**. **:*: . * . * ** ******:* : ** .*.************:**:****.::*:: :. : .*** :** .*: * . ** *.. .. : ..::* . *:****:****:.**:**** . :.. *.: . * ...*:*: .. * .*: . ..: .**:*: * * **.**:**:***:.. :.* .:.*: :.: : ::. . * . . ..* .. : : .*. * :: :***************** .** :: .... :.:*.**:** : ** .*********.* **.: * . .: .* * *** *** ** .***.. . : : *..* * * :* : .. .. .**. ::. *.:: ********.:****** ** . : ...* : :..******* *. :* : ***** *: .:: * .. : : * * ** .* :*. : . * *:** . ****************.. . . .* :****:**:*: ::.. . .**. *: *:*:*:.:::.* ... . * ..*:.*: ****.*******.:::: :* *.**:.**.*::.*.**: .:*:: . : **. *.*****:** * . . . : ..: : :.: . : : .. .* :: . : . : ", "identical_positions": 319, "similar_positions": 325, "identity": "22.5%" }, { "cls_id": "homologset.agr.MGI:2140675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L3E1-1", "uniprot_id": "A0ABK0L3E1_RAT", "id": "A0ABK0L3E1-1", "name": "", "aln": "----------MVNSLLFGEMALAFGCPPGGGG--CASGGGGGG-AGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERDRRLRYKTFSREQAVQTGPELLRPPAAGGGQAL--GAATGVNANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKCMNLQTMVDTLQEAAQEAEAIQEEMNEKIERLKAELVVFKGLMSDP--------------------MTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQ--------------VVPKKKDRKVASDDDISEQDGEVNRFSDEEVGSMNITDEMKRMFNQL----------RETFDFDDDCDSLTWEENEDTLLLWEDFTNCNPTIDLQG-----------------------------EQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKG--SADRNSPSPSSVASSDSGSTDEIQDDLE----READVEPMVS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2V2-1", "uniprot_id": "IFFO2_MOUSE", "id": "Q8R2V2-1", "name": "Intermediate filament family orphan 2", "aln": "----------MVNSLLFGEMALAFGCPPGGGG--CAGGGGGGG-AGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERDRRLRYKTFSREQAVQTGPELLRPSAAGSGQAL--GAATGVNANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKRMNLQTMVDTLQEAAQEAEAIQEEMNEKIERLKAELVVFKGLMSDP--------------------MTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQ--------------VVPKKKDRKVASDEDISEQDGEVNRFSDEEVGSMNITDEMKRMFNQL----------RETFDFDDDCDSLTWEENEDTLLLWEDFTNCNPTIDLQG-----------------------------EQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKG--SADRNSPSPSSVASSDSGSTDEIQEDLE----READVEPMVS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TF58-1", "uniprot_id": "IFFO2_HUMAN", "id": "Q5TF58-1", "name": "Intermediate filament family orphan 2", "aln": "----------MVNSLLFGEMALAFGCPPGGGGGGCPGGGGGGGGAGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERERRLRYKTFSREQAVQTGPELLRPPAPGGGHGLSSGAAAGANANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKRMNLQTMVDTLQEAAQEADAIQEEMNEKIERLKAELVVFKGLMSDP--------------------MTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQ--------------VVPKKKERKVASDDDISEQDGEVNRFSDDEVGSMNITDEMKRMFNQL----------RETFDFDDDCDSLTWEENEDTLLLWEDFTNCNPTIDLQG-----------------------------EQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKG--SADRNSPSPSSVASSDSGSTDEIQDEFE----READVEPMVS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B974-1", "uniprot_id": "A0A8M2B974_DANRE", "id": "A0A8M2B974-1", "name": "", "aln": "MDLPRRFPDPVLNPMLFTESPVPLGINE-----ACAVGSGSGP-------TATSALRNDLGSNIHVLKTLNLRFRCFLSKVHELERRNKLLEIQLQHAQEQA--RYR-QLFSREQAVQTNLEQPY---------------------------------SNAQCQSRLPGKIWSFSHTARYG-GRFETRQGPGVSWTHPDGVGVQIDTITPELRALYNVLAKVKRERDEYRRKWEEEVSKRQQMESLVETLQETVQSSEVAQGELNEKVERLKTELVVFKSLMPND-------------------EVSDLDSKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDMTKILHGSSSRASVEQKGGMVVCRRKECKGDSEEQRVEADGDCTHHEEDVPASLNITDEMKRMLNQLGCSANWFVGRRETFEFDDDCDSLAWEETEETLLLWEDFSHYNSLNSNTTSAHTTTTSTAAAGTAVSMSCASESHGETHEQDRSLGSLIHETESLFKTREQEYQDTIGQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLIQSTAPTGRQSPSLSSVASSDSGNTDDIQDELEPDGLKDGEKDGEVEMNGEVR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q7X1-1", "uniprot_id": "A0A8M9Q7X1_DANRE", "id": "A0A8M9Q7X1-1", "name": "", "aln": "-----------MSSLLFGEG--FLGG---------AVSGAPSD-------AVPRALRNDLGSNIHVLKTLNLRFRCFLAKVHELERRNKLLESQLKQATGQP--RYPGFSFTREVAVQT-----------------------------------------DSLESRLPGTIWSFTHILRHG-ERVKTVQGPGVTWTHPDGVGVQIDTITPELRALYNVLAKVKRERDEYKRKWEEELSRREQMEVMVQSLQENVNQSEAIQDELNEKVERLKAELVVFKSLMSDAGGRRRNKAVENQRKILDLKQMSDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDMSKIFS--PSRAPADR---AVACRKKERKAVSDEESSEMDADPSSTSEED-APFNITDEMKRMLNQLHCSDNSFVARRETFEIDDDCDSLTWEENDDTLLLWEDFTNYNVPCSALTNGNG--------------DCSTDG----HEADSSLGSLIDETESLFKTREQEYQKTIGQIEMELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRMIKG----GRNSPSISSSASSDSGNTDEIQEESD----KDGETDGPIS------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:** * :* . ... . ... ***:*******:** **:******:*********:*** **:: : * *:** **** . .****.***::: * * .:* *****:*.***************:*****************:*:****::: ::: :*::*** .:.::. * *:***:****:******.**.: ::***:**********************************::**: *. ::*: * *::: * *.: . .:: ..:*********:*** ****::*******:***.::********:: * . * : .**.**.****:****::***.******:******.****************************:*:. .*:*** ** ******.**:**:: : ::.: : :. ", "identical_positions": 273, "similar_positions": 115, "identity": "44.61%" }, { "cls_id": "homologset.agr.MGI:2140680", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M951-1", "uniprot_id": "CA174_RAT", "id": "Q5M951-1", "name": "UPF0688 protein C1orf174 homolog", "aln": "MRSRKLTGGVRSSARLRARSCSSTSLASAGDIASSTSAKTTCLASSSHKATDRRTSKKFKYDKGHLLKAELQKVDPKSDISSLPKVVPVAPCENKFAED-----GAEAAVPAPE-NTAPPQGCSKPVSEEPSVKAEEGLPTAPRSAAAAQETHDSS---ASQAEPVP--------VLQMDSSVFLDDDSNQPMPVSRFFGNVELMQDLPPASSSCPSMSRREFRKMHFRAKDDDEDAEG----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WR5-1", "uniprot_id": "CA174_MOUSE", "id": "Q80WR5-1", "name": "UPF0688 protein C1orf174 homolog", "aln": "MRSRKLTGGVRSSARLRARSYSSASLASARDVTSSTSAKTTCLASSSHKATDRRTSKKFKYDKGHLVKAELQKLDPKSDISSLPKVAPVAPCENKFAED-----SAEAAVSVPE-SREPPQGCSTPASEEPSVKAENGLSTEPSSAAAAQEPDDSS---AGQAEPVPRTEEVRASVLQMDSSIFLDDDSNQPMPVSRFFGNVELMQDLPPASSSYPSMSRREFRKMHFRAKDDEDDAEG----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYL3-1", "uniprot_id": "CA174_HUMAN", "id": "Q8IYL3-1", "name": "UPF0688 protein C1orf174", "aln": "MRSRKLTGAVRSSARLKARSCSAARLASAQEVAGSTSAKTACLTSSSHKATDTRTSKKFKCDKGHLVKSELQKLVPKNDSASLPKVTPETPCENEFAEGSALLPGSEAGVSVQQGAASLPLGGCRVVSDSRLAKTRDGLSVPKHSAGSGAEESNSSSTVQKQNEPGLQTEDVQKPPLQMDNSVFLDDDSNQPMPVSRFFGNVELMQDLPPASSSCPSMSRREFRKMHFRAKDDDDDDDDDAEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L9C7-1", "uniprot_id": "CA174_DANRE", "id": "Q1L9C7-1", "name": "UPF0688 protein C1orf174 homolog", "aln": "---------------MRAKQTVVVSLG--QRVCGAVSLNPPGVKSSVKKAAKRR--VLLQRSAPDIARAVRQMAGDGGEAKRLPKR----PFHGEVEEN------SSAAVDGNVKIQPGKKAPGERRGKENSAAKCTGLTSGSAEAKMEQSVHGSQ---------------------TTDPSVFFDEDSNHVFPVEQFFGNLDVVEDYPRRTPGSKRMTRREYRSMHYYAKEDSEEEHL----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:. . *. : .:.* :.. : ** :**:. * :: . .: :: * .: *** * ..:. *. :.*.* . ... . **. .* . .*. * *:*:*:***: :**.:****:::::* * :.. *:***:*.**: **:*.:: . ", "identical_positions": 45, "similar_positions": 68, "identity": "18.52%" }, { "cls_id": "homologset.agr.MGI:2140712", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TL4-1", "uniprot_id": "PHF24_MOUSE", "id": "Q80TL4-1", "name": "PHD finger protein 24", "aln": "MGVLMSKRQTVEQVQKVSLAVSAFKDGLRDRPSIRRGGE----LPGSRRGTVEGSVQEVQEEKEAEASAPVVQ------EESSINRAAWERLRDGRGVEPEEFDRTSRFTPPAFIRPTRKLDDDKPPDICLEPREPVVNDEMCDVCEVWTAESLFPCRVCTRVFHDGCLRRMGYLQGDSAVEVTEMAHTETGWSCYYCDNLNLLLTEEEMYSLTETFQRCKVIPDCSLTLEDFVRYRHQAAKRGESSRALTDEQEEQAARQFAALDPEQRGHVEWSDFLSHESLLLLLQLRPQNSLLRLLTVKERERARATFLARG--RGSTISEAECHHARHSWFCKRLTEAPSC------------SVSISHVGPIADSSPAASSS-KSQEKALLPTEQESRYVDWPTFLRENVIYILAARPNSGAIHLKPPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GMB9-1", "uniprot_id": "A0A8I6GMB9_RAT", "id": "A0A8I6GMB9-1", "name": "", "aln": "MGVLMSKRQTVEQVQKVSLAVSAFKDGLRDRPSVRRGGE----LPGSRRGTVEGSVQQVQEEKEAEASAPGVQ------EESSSNRAAWERLRDGRGVEPEEFDRTSRFTPPAFIRPTRKLDDDKPPDICLEPRESVVNDEMCDICEVWTAESLFPCRVCTRVFHDGCLRRMGYLQGDSAVEVTEMAHTETGWSCYYCDNLNLLLTEEEMYSLTETFQRCKVIPDCSLTLEDFVRYRHQAAKRGDSTRALSDEQEEQAARQFAALDPEHRGHVEWPDFLSHESLLLLQQLRPQNSLLRLLTVKERERARATFLARG--RGSTISEAECHQARHSWFCKRLAEAPSC------------SVSISHVGPIADSSPAGSSS-QSQEKALLPTEQESRFVDWPTFLRENVIYILAARPNSGAIHLKPPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPV7-1", "uniprot_id": "PHF24_HUMAN", "id": "Q9UPV7-1", "name": "PHD finger protein 24", "aln": "MGVLMSKRQTVEQVQKVSLAVSAFKDGLRDRPSIRRTGE----LPGSRRGTVEGSVQEVQEEKEAEAGTSVVQ------EESSAGRAAWERLRDGRGVEPEEFDRTSRFTPPAFIRPTRKLDDDKPPEICLEPREPVVNDEMCDVCEVWTAESLFPCRVCTRVFHDGCLRRMGYIQGDSAAEVTEMAHTETGWSCHYCDNINLLLTEEEMYSLTETFQRCKVIPDCSLTLEDFLRYRHQAAKRGDRDRALSEEQEEQAARQFAALDPEHRGHIEWPDFLSHESLLLLQQLRPQNSLLRLLTVKERERARAAFLARG--SGSTVSEAECRRAQHSWFCKRFPEAPSC------------SVSISHVGPIADSSPASSSS-KSQDKTLLPTEQESRFVDWPTFLQENVLYILAARPNSAAIHLKPPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QKZ1-1", "uniprot_id": "A0A8M9QKZ1_DANRE", "id": "A0A8M9QKZ1-1", "name": "", "aln": "MGVLMSKKQQVEKVQKCSVVVSAFKDGLKDRAAPAAADQTDDVITENGDGSAEGAQHTDKEHPELKDKDSRPNQQAPPTEEQRANQEAWGRLRDGKGVEPEDLKKAHQLIPPAFVRPKRDVNDDQPVDVMLGQREQPVNDEMCEVCEVWTADDLFPCRTCTRVFHDGCLREMGYLSTEALQEMRETAHTTTGWSCYYCDNVNLLLTEEEMYSLMETFKQCKIIPESCLVSDELLQYRHFVTKQ-LFERDLTDEEEEEVLAQFAALDPEKKGQIEWSDFLYHETLSVLQKFRTENSLVRILTAKERDRARALFQSIDQDKDAIITAGEARKAQTSWFQKTNKESQSCNVRLMGLCSPLFSMGISHVGPISESSPASSSSERSRDKAME---SDNRPVTWDNFLKESAIYILAARPNSSAMHIRLPL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:* **:*** *:.********:**.: .: :. . *:.**: : :*. * : . : **. .: ** *****:*****::.:: :: ****:**.*.::**:* :: * ** ******::******:.*****.***********.***:. :: *: * *** *****:****:************ ***::**:**:..*. :::::*** .:*: * *::*:**:. ********::*::**.*** **:* :* ::*.:***:*:**.***:**** * : . .: :: .*.::*: *** * *: ** *:.*******::****.*** :*::*:: .:.* * * .**:*..:*********.*:*:: * ", "identical_positions": 207, "similar_positions": 122, "identity": "48.71%" }, { "cls_id": "homologset.agr.MGI:2140726", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHF8-1", "uniprot_id": "D3ZHF8_RAT", "id": "D3ZHF8-1", "name": "", "aln": "--------MWALAGR---------ALAPWAAGAARLLPPCPRHAGVL--------------EPGVACRLFSAAELK---EKP-------DMSRFPVEDIRNFSIIAHVDHGKSTLADRLLELTGTIDKTQKNKQVLDKLQVERERGITVKAQTASLFYSFG--GKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVGKQIEKVFDIPSEECIKISAKLGTNVDSVLQ-AVIERIPPPKVHRANPLKALVFDSTFDQYRGVVASIALFDGMLSKGDKIVSAHTKKTYEVNQVGILNPNEQPTHKLYAGQVGFLIAGMKDVTEAQIGDTLYLHNHP--VEPLPGFKSAKPMVFAGVYPIDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYKEKEITIINPAQFPD----KSKVTEYLEPVVLGTVITPTEYTGKIMELCQARRAIQKNMTFIDEN-RVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTADLIKMDILLNGNIVEELVTVVH--------REKAYTVGKSICERLKDSLPRQLFEIAVQAAIGSKVIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKIGNIEIPKNAFIKVLKTQPNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3X4-1", "uniprot_id": "GUF1_MOUSE", "id": "Q8C3X4-1", "name": "Translation factor Guf1, mitochondrial", "aln": "--------MWALVGR---------ALAPWAAGAR--------HAAAS--------------EPRAACRLFSAAELK---EKP-------DMSRFPVEDIRNFSIIAHVDHGKSTLADRLLELTGTIDKTKKNKQVLDKLQVERERGITVKAQTASLFYSFG--GKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVGKQIEKVFDIPSEECIKISAKLGTNVDSVLQ-AVIERIPPPKVHRENPLKALVFDSTFDQYRGVIANIALFDGVVSKGDKIVSAHTKKAYEVNEVGILNPNEQPTHKLYAGQVGFLIAGMKDVTEAQIGDTLYLHNHP--VEPLPGFKSAKPMVFAGVYPIDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYKEKEITIINPAQFPE----KSQVTEYLEPVVLGTVITPTEYTGKIMALCQARRAIQKNMTFIDEN-RVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNMVEELVTVVH--------REKAYTVGKSICERLKESLPRQLYEIAIQAAVGSKVIARETVKAYRKNVLAKCYGGDITRKMKLLKRQSEGKKKLRKIGNIEIPKDAFIKVLKTQPNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N442-1", "uniprot_id": "GUF1_HUMAN", "id": "Q8N442-1", "name": "Translation factor GUF1, mitochondrial", "aln": "--------MWTLVGRG---WGCARALAPRATGAALLVAPGPRSAPTLGAA----------PESWATDRLYSSAEFK---EKL-------DMSRFPVENIRNFSIVAHVDHGKSTLADRLLELTGTIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNCE--GKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVENQIEKVFDIPSDECIKISAKLGTNVESVLQ-AIIERIPPPKVHRKNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQPTHKLYAGQVGYLIAGMKDVTEAQIGDTLCLHKQP--VEPLPGFKSAKPMVFAGMYPLDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSSKLIKEHREKEITIINPAQFPD----KSKVTEYLEPVVLGTIITPDEYTGKIMMLCEARRAVQKNMIFIDQN-RVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNTVEELVTVVH--------KDKAHSIGKAICERLKDSLPRQLFEIAIQAAIGSKIIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKIGNVEVPKDAFIKVLKTQSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T7J6-1", "uniprot_id": "A0AB32T7J6_DANRE", "id": "A0AB32T7J6-1", "name": "", "aln": "--------MMSLLRPHGLFLPFIKRLTDIKVCRVKRRSQGCTYNITVIRHR-------WMKSLGSVRDLSSSATEK---ETF-------DMSKFPAERIRNFSIIAHIDHGKSTLADRLLEMTGAIAKTASNKQVLDKLQVERERGITVKAQTASLFYQHH--GQTYLLNLIDTPGHVDFSYEVSRSISACQGVLLIVDANQGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIETVFDIPKEECIRISAKLGTNVEQVLQ-EVVKRIPPPAVRVEDPFKGLVFDSTFDHYRGVVANIALFGGRVSRGDRIVSAHLGKSFEVNELGILRPDQHPTETLYAGQVGYVIAGMKEVKEAQIGDTLYLHKQP--VEALPGFKPAKPMVFAGMYPMDQSEYTALRSALEKLTLNDSSVSIQKDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVIITAPTVPYKAVLASAKLIKEYGEEVITIINPAQFPD----KSKVLEYLEPMVTGTIITPDDFTGKIMTLCQGRRGIQKNMVYIDDH-RVMMKYVFPLNEIVVDFYDQLKSMSSGYASFDYEDAGYEAADLIKMDFLLNGQPVEELAVIVHKLWFLLIFRDKAYSSGKAICERLSNSIPRQMFEIAVQAAIGSKIIARETIKAFRKNVLAKCYGGDITRKMKLLKKQAEGKKKMRRIGNIDVPKDAFISVLKRK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRH6-1", "uniprot_id": "GUF1_DROME", "id": "Q9VRH6-1", "name": "Translation factor waclaw, mitochondrial", "aln": "MIVGYSVFFHHTVTRRTWCAVTIFFCRQRNVNSAMIRAISIRWLLQRPGDKRHSAWLVARSKSLLVRNLSTTNQVKGETEEPSQADLLREFAHMPVERIRNFSIIAHVDHGKSTLADRLLELTGAIARNGGQHQVLDNLQVERERGITVKAQTASIFHRHK--GQLYLLNLIDTPGHVDFSNEVSRSLAACDGVVLLVDACHGVQAQTVANYHLAKQRQLAVVPVLNKIDIKHANPDQVCQDLKLLFGIDPDEVLRVSAKLGTGVSEVLE-RVIETVPPPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGKLEQNQDIQSLATKKVYSVKSISVLRPAECPVPDVSAGQVGLIACNMRNSKESIVGDTIHLKNQA--VAAAGSYRPQQPLVFAGVFPADQSKHVALRSAIDKMVLNDSAVTVKIDSSPALGQGWRLGFLGLLHMEVFCQRLEQEHGAEPIITAPSVTYRLVLSNPKMIKQQGRDTMDISNAALFPE----PHSIKEYYEPLVLGTIITPTEYVGQVISLCVERRGLQQSSVNIDDT-RVLMKYVLPLSEIILDFHDRLKSLSSGYASFSYEDHGYHPSHLVRLDIHLNGKPVEELCRIVH--------VSKATGVARQMVLKLRELIPKQMVQIAIQACVGSKVLARETIKAYRKDVTAKLYGGDVTRRMKLLKQQAEGKKKMRMFANIRVPHETFINVLKR----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46943-1", "uniprot_id": "GUF1_YEAST", "id": "P46943-1", "name": "Translation factor GUF1, mitochondrial", "aln": "--------MLKFRIR-----------PVRHIRCYKRHAYFLRYNHTT----------------------TPAQKLQ------------AQIEQIPLENYRNFSIVAHVDHGKSTLSDRLLEITHVIDPNARNKQVLDKLEVERERGITIKAQTCSMFYKDKRTGKNYLLHLIDTPGHVDFRGEVSRSYASCGGAILLVDASQGIQAQTVANFYLAFSLGLKLIPVINKIDLNFTDVKQVKDQIVNNFELPEEDIIGVSAKTGLNVEELLLPAIIDRIPPPTGRPDKPFRALLVDSWYDAYLGAVLLVNIVDGSVRKNDKVICAQTKEKYEVKDIGIMYPDRTSTGTLKTGQVGYLVLGMKDSKEAKIGDTIMHLSKVNETEVLPGFEEQKPMVFVGAFPADGIEFKAMDDDMSRLVLNDRSVTLERETSNALGQGWRLGFLGSLHASVFRERLEKEYGSKLIITQPTVPYLVEFTDGKKK--------LITNPDEFPDGATKRVNVAAFHEPFIEAVMTLPQEYLGSVIRLCDSNRGEQIDITYLNTNGQVMLKYYLPLSHLVDDFFGKLKSVSRGFASLDYEDAGYRISDVVKLQLLVNGNAIDALSRVLH--------KSEVERVGREWVKKFKEYVKSQLYEVVIQARANNKIIARETIKARRKDVLQKLHASDVSRRKKLLAKQKEGKKHMKTVGNIQINQEAYQAFLRR----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : :: ::* * *****:**:*******:*****:* .* . ::****:*:********:****.*:*: *: ***:********** ***** ::* *.:*:*** .*:*******:.** . * ::**:****:: :: .:* .:: * : :: : :*** * .*..:* ::. :*** : . ::.*:.** :* * *.: : :..* : :.: : . : :.*:.:.:: * . .. : :**** : .*:: .*: :***: .: . .:. :*:**.* :* * :. : . :.::.*** :*::. ::* *** ******** ** .** :***:*:.:. *:* *:*.* ::. * * *. **: .: : **.: ..: * :: *.:: ** .*. * . :: :*::** :**..:: **.. ***:* *:**:.*** **. :.:::::: :**: :: * ::* .:. .: :: : : *: ::.:** ..*::****:** **:* * :..*::*: *** :* ****::: ..*: : :::: .*: ", "identical_positions": 210, "similar_positions": 228, "identity": "29.25%" }, { "cls_id": "homologset.agr.MGI:2140729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2P3-1", "uniprot_id": "ZFN2A_RAT", "id": "Q5U2P3-1", "name": "AN1-type zinc finger protein 2A", "aln": "MEFPDLGKHCSEPTCKQLDFLPITCDACKQDFCKDHFSYSGHKCPFAFKKDVQVPVCPLCNAPIPVRRGDIPDVVVGEHMDRDCTFHPGRNRNKVFTHRCSKEGCRKKEMLQLACAQCHGNFCIQHRHPLDHNCQ---AGSSSVSRG------------RSSASRAAEQK----PSGVSWLAQRLR-RTVK------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JII7-1", "uniprot_id": "ZFN2A_MOUSE", "id": "Q9JII7-1", "name": "AN1-type zinc finger protein 2A", "aln": "MEFPDLGKHCSEPTCKQLDFLPITCDACKQDFCKDHFSYVGHKCPFAFKKDVQVPVCPLCNAPIPVKRGEIPDVVVGEHMDRDCTFHPGRNRNKVFTHRCSKEGCRKKEMLQLACAQCHGNFCIQHRHPLDHNCQ---AGSSSASRG------------RTSTSRAAEQK----PSGVSWLAQRLR-RTVK------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6M9-1", "uniprot_id": "ZFN2A_HUMAN", "id": "Q8N6M9-1", "name": "AN1-type zinc finger protein 2A", "aln": "MEFPDLGKHCSEKTCKQLDFLPVKCDACKQDFCKDHFPYAAHKCPFAFQKDVHVPVCPLCNTPIPVKKGQIPDVVVGDHIDRDCDSHPGKKKEKIFTYRCSKEGCKKKEMLQMVCAQCHGNFCIQHRHPLDHSCR---HGSR-------------------PTIKAG------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQQ7-1", "uniprot_id": "Q9VQQ7_DROME", "id": "Q9VQQ7-1", "name": "AN1-type domain-containing protein", "aln": "MEFPHLGQHCSEATCNRLDFLPVKCDSCDKVFCASHYSYDRHSCPGAYKKNVQVPVCPLCREPVPTPPGVEPDVTVGQHIDQQCKSES----KKIYTNRCNAKGCKRKELIPVTCSQCRLNFCLRHRHTSDHDCKPVPASSTTSSRGGFQSIFKTSSDSRSMAAQAAERRQNRRPASNSISNTNSRPRPVQATQVQNIQGNMSEDEALARALALSIMEQDDAAESNRQAPAPSNAQQVAVGGGGNQQGNGKDKCLLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.**:**** **::*****:.**:*.: ** .*:.* *.** *::*:*:*******. *:*. * ***.**:*:*::* .. :*::* **. :**::**:: :.*:**: ***::***. **.*: .* : :*. ", "identical_positions": 70, "similar_positions": 49, "identity": "27.24%" }, { "cls_id": "homologset.agr.MGI:2140750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RRE4-1", "uniprot_id": "Z518B_MOUSE", "id": "B2RRE4-1", "name": "Zinc finger protein 518B", "aln": "-----MKDIGEQLYTTQVNGGPSSLTMSPKQP--NRATRTERQEAQTLLYQGSEAEAATMTIATCVQCKSVHKIPTQDLRKGPGQSQDTYVCFKCSLRAVPTQLHFVNNNAGAAHVRNETETISSPVN-KFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQHEEIRFICSHCSYISYTKGEFQRHLVKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHERAGAKRPFKTVAKLEPKRTSIPKQSMELSKGPSPRAAFQNKLSDQLSRFSLHANKDKTHNLMLLPELKKYQKDVVCIPNKVTLSEPREVSLLGNKNVEVEVLSPSKEPVHPGMPLTVMAPSELVVPTNCLAQLMDVKVVNGAQQLVLKLFPLEENARLETSRGDGGTSECLSTEKGSGGQKKMLSPEASRSLAVEGNAGDFVGLDRLHSLVQKQLKNVKWVKSCNFFMPNSGVHSQQESFLGSDTIKELQKSHSLCPPR-ALPSAAIKSHSPASVQN-SVPYGPGATVSHFLSKAAVAFADDRRGARSNSQQLLPLASLPSKVPFSGEKGLLPIGESDLEARNRISRPETLVSSDRKLED-KQMESKAVGNTGQVSSVQNKEYLHINITGEDKPRSQQPGDQPGQPKTSETAGATFEGPIISSVFSLSSGSENVPEAIKWNSSTTKIKSIELLRRKIAQLIESCGKPSSLSANSAQRRSIGQAPKLTSKATPKAIQEMSVSLTGPGPTPGPSVGPLQKPPNEDSITGSRQLVPQQVCPQFISANDGKMENRVTRKTPVATPVLIPKGAVLRVLNSSEDAHIIEATCDTPVSIPCSEAQLAGTLPFCPMKQTGSGSQPLTCRSGPADMSPGLETSLRPKSRKEDTICSATAKKMVPVYSTAPGSSDSIRQGRPVSRNLTVSKNKTKQVNSTKKKNKMQANPGRYFKDPPSFFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGVRRYHMRLTYQNVAETNHMKRQMMLKMKLKKVHKNNYQVVGSMPDDPAQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABC6-1", "uniprot_id": "D4ABC6_RAT", "id": "D4ABC6-1", "name": "Zinc finger protein 518B", "aln": "MQLREMKDIGEQLYTTQVNGGPSSLTMSPKQP--NRATRPERQEAQTLLYQGSEAEAATMTIATCVQCKSIHKIPTQDLRKGPGQGQDTYVCFKCSLRAVPTQLHFVNNNAGAAHIRNETETISSPVN-KFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQHEEIKFICSHCSYISYTKGEFQRHLVKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHERAGAKRPFKTVAKLEPKRTNISKQSMELSKAPSPRAAFQNKLSDQLSRFSLHASKDKTHNMMLLPELKKYQKDVVCIPNKVTLCEPREVSLLGNKNVEVEVLSPSKEPVQPGLPLTVMAPSELVVPTNCLAQLMDVKVVNGTQQLVLKLFPLEENSRLETSRGDGGVSECTTTEKGSGGQTKVLSTEASRSLAMEGNAGEFVGLDRLHSLVQKQLKNVKWVKSCNFFMPNSGIHSHQDSFLGPDTIKDLQKSHSLCPPR-ALPSASVKSHSPASVQS-SVSYGPGATVSRFLTKAAAAFAEDGRGSRSDSQQLLPLASLSSKVSFSGEKGLLPLGENDLEARNRTSRPETVVSSDRKLED-KPMESKAVGSTSQVSSVQKKEYLHINFAGEDKTRSQQPGGRPVLPKTSETAGNAFEGPIISSVFSLSSGSENVPEGIKWNSSTTKIKSIELLRRKIAQLIESCGKPSSLSAGSPQRRPIGQAPKLTSKATPKAIQEMSGSLTG----PGPSVGPLQKPQNEDSITGSGQHAPQQMCPPFVSANDGKTESRVTRKTPVATPVLIPKGAVLRVLNSSEDARIIEATCDTPVSIPCSEAQLAGTLPFCPVKQPGSGSQLLPCRSGPADLSPSLETSLRPKSRKEDPICSVTPKKIIPVYSTVPGSSDSSRQGRPVSRNLTVSKNKTKQVSSAKKKNKMQANPSRYFKDP-SFFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGVRRYHMRLTYQNVAETNHMKRQMMLKMKLKKVHKNNYQVVGSLPDDPAQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C0D4-1", "uniprot_id": "Z518B_HUMAN", "id": "Q9C0D4-1", "name": "Zinc finger protein 518B", "aln": "-----MKDIGQQLYTTHLNGGHNSLTMSPKQPDANGAPRPNRQEAQTLLYQGSEAEAAMMTIATCAKCKSVHKISLQDLQKGTGK-DGMYVCFQCSLGAAPPNFHFVSNNSSATHVGNKTENFSSSVNSKFKVRNFKPGKYYCDKCRFSTKDPLQYKKHTLQHEEIKFICSHCSYISYTKGEFQRHLVKHTGIFPYQCEYCDYGAIRNDYIVKHTKRVHERAGAKRPVKAVAKLEPKRTGTSKQNPELLKASNPRTTFQNKWSDQLSGFSLHANKDKMHNIMLLPEPKEYQKDVVCIPNKMTLSEPNEVNLFENKNVEVEVLSPAKEPVQPGMPLTVVAPAELVVPANCLAQLIDVKVVNGTQQLVLKLFPLEENNCLEAGRDNGGNSERMVKEKGSNEQEKVLSAEKTKSLTVDGNVGKLVGIDSFQPSVQKQLKNVKWVRSYDFIMPNSSVHNNGKSFINSETIEDFQKKNNLYPHRTAFPSVALKGHSLASVFKNSVLRSLGAASNPFPYKAAVCFAESGRNLHSSSQQLLPFAASPATCSFSGEKGLLPVSENDLESTSKVNIPVKVVSSNRKQEDNQTEEHKAVSTVGQISSQHKSEYLHINITGED--RSQQPGDKPLELKNSERTNNTNDGPVISSVFSLSSGSENVPEGIKWNSSTSKIKSIELLRRKIAQLIESCGKPSSLASNSAHRRSVGQASKGTSKATSEGIQEINVSLTG----LGHSTGTLQKPPNDGGITGNRQLTHQQIYPHFADGSNRKTKSRVARKAHVATPVLIPKGAVLRVLNSSENAHIIEATCEAPVSIPCSERQLIKPVPFCPVRQADSDLQPLRSERGPIDMSPNIETPLRPKLRKESAVCSTIHRKTGLLYGQQ-GSSELNKQGRLLSRSLSISRNKTKQVHLSRKKNKIQAEPSRCLKDP-SIFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGIRRHHVRLTYQNAEEASQIKRQMMLKMKLKKVHKNNYQVVDSLPDDSSQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:*****::*** .********* * *.*.:***************** ******.:***:***. ***:**.*: :. ****:*** *.*.::***.**:.*:*: *:**.:**.** ***************************:*********:*****************************:***************** :***********.*:*********. .**. ** *...**::**** ***** *****.*** **:***** *:***********:**.**.**.*: ***********:****:**:****:**:*****:******:*******:************* **:.*.:** ** .****. * *:**.* ::**:::**.*.:**:* ::. ***********:* :*:****.:*.: .**:..:**:::**.:.* * * *:**.::*.** *** . ** . **: . * ***..**:. *. :*.******:*: .:. .*********:.*.***: .: . * .:***:** ** : * ***....*:** ::.******::*** ******.:* *.** :. : :**:****************.*******:*************************::.*.:**.:***.* *****.:.***:. **** * *.*.**** *:..***. * . **: * * ...: * :.**:**: ********************:*:******::******** ** .:****::*..*. * * .. ** *:**.:**.**** ***..:**. :* :*. ***: :*** :**.*::*:****** ::****:**:*.* :*** *:********************************************************************:**:*:******. *:.::*********************.*:***.:******************************************", "identical_positions": 742, "similar_positions": 230, "identity": "68.2%" }, { "cls_id": "homologset.agr.MGI:2140767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2J7-1", "uniprot_id": "RELL1_MOUSE", "id": "Q8K2J7-1", "name": "RELT-like protein 1", "aln": "MALWGLPGSAVLAASVFVGGAVSSPLVAADNTGSHTLHSRAETTPSSPTNNPGNGHPEYIAYVLVPVFFVMGLLGVLICHLLKKKGYRCTTEAEQEVEEEK------VEKIELNDSINE-NSDTVGQIVQYIMKNEANADILKAMVADNSVGDIESPVTPSTPGSPPVSPGPLSPGA--TPGKHVCGHHLHTVGGVV-ERDVCQRCRHKRWHFIKPTNKTKEGRPRRQGEVTVLSVGRFRVTKVEHKSNQKERRSLMSVSGIESVNGDVPATPVKRERS------------DTE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUW5-1", "uniprot_id": "RELL1_HUMAN", "id": "Q8IUW5-1", "name": "RELT-like protein 1", "aln": "MAPRALPGSAVLAAAVFVGGAVSSPLVAPDNGSSRTLHSRTETTPS-PSNDTGNGHPEYIAYALVPVFFIMGLFGVLICHLLKKKGYRCTTEAEQDIEEEK------VEKIELNDSVNE-NSDTVGQIVHYIMKNEANADVLKAMVADNSLYDPESPVTPSTPGSPPVSPGPLSPGG--TPGKHVCGHHLHTVGGVV-ERDVCHRCRHKRWHFIKPTNKSRESRPRRQGEVTVLSVGRFRVTKVEHKSNQKERRSLMSVSGAETVNGEVPATPVKRERS------------GTE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QK31-1", "uniprot_id": "F1QK31_DANRE", "id": "F1QK31-1", "name": "", "aln": "-----MAGSSLSTNSTTRGG----------NG-----HS-------------GDGHPENIAFILVPFFFLMGLLGVLICHILKRKGYRCTTEAEEEEQLEKERRDEELEKGDLNDTFSEGNADTVGQIVHYIMKNEANSDALKAMVQD-SIDSEGGPVTPTTPNTPTSPESPAAPGLPPTAAKHTC-NHLHTIGGISGHKNICHRCNQKKWPLLRRSSSKKLDRRSHVGEVTVLSVGRFRVTKCDPKT-ARERRTLLITEPNGSVS-PSPASTHPPEHTPVLQLPKIDVIEEHEN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.**:: : :. ** * ** *:**** **: ***.**:***:******:**:**********:: : ** :** :***:..* *:*******:********:* ***** * *: . .****:**.:*. . .* :** *..**.* :****:**: .:::*:**.:*:* ::: :...: .* : *************** : *: :***:*: .. :*. **:. *:: * ", "identical_positions": 123, "similar_positions": 72, "identity": "41.69%" }, { "cls_id": "homologset.agr.MGI:2140770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XAX4-1", "uniprot_id": "A0A8J8XAX4_RAT", "id": "A0A8J8XAX4-1", "name": "", "aln": "MPWKLANTPIWRLDRFIQDHLLPDTTFLTE-------------------------------GGCYDEYSMLKGRSEATLVVFLNNLTCFEDQLKRREEFIEEIWKHLCQLQQEKQFKLNFEFQTSEQANSRSLSIKLSSPQLQQEVEFDVQPAYDVLYAWRYNKYLDPRIYNKIYASLIRESTNLDKEGEFSVCFTELQQHFLKHPGHKMWNLIRLVKYWYQLCKEKLGDLLPPQYALELLTVHAWELGIENTCELYIARGFRSVLELIIKYRCLLIFWTLCYDFNHNEVSEYLNKQLQKDRPVILDPADPTRNVAGSNLQAWHLLAEEAGAWVQSSFFRNSDMSLVHSWKVPPEKQ---------------------------------------------TCVIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI95-1", "uniprot_id": "OAS1D_MOUSE", "id": "Q8VI95-1", "name": "Inactive 2'-5'-oligoadenylate synthase 1D", "aln": "MARELFRTPIWRLDKFIEDQLLPDTTFLTELRADIDSISAFLMERCFQGAAHPVRVSRVVMGGCYNEYTVLKGRSEANMVVFLINLTSFEDQFNGQVVFIEEIWRHLLQLQQEKLCKLKFEVQSPKEPNSRFLSFKLSCPERQHELEFDVQPAYDALYEVRHFKPFDSSNYNKVYAQLTHECTTLEKEGEFSICFTDLHQSFLRYRAPKLWNLIRLVKHWYQLCKEKLRGPLPPQYALELLTVYVWEYGIHENPGLHTAQCFRTVLELVTKYKRLRIYWTWCYDFQH-EISDYLQGQIKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQIWIDSTFFTNHDMSIVEAWEVMPERQ---------------------------------------------ECVFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00973-1", "uniprot_id": "OAS1_HUMAN", "id": "P00973-1", "name": "2'-5'-oligoadenylate synthase 1", "aln": "-MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNP----QIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLG-KLPPQYALELLTVYAWERGSMKT-HFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLAESNSADDETDDPRRYQKYGYIGTHEYPHFSHRPSTLQAASTPQAEEDWTCTIL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .** **:**:* ***** * : **. .: : *:***:* :**** ** *:**:: : **:** ::* *:*: .::**.*:.. *.* **: **. : . :**** **:*.* :. ::*..* .*.* *:****** ***:*:: **: *: .******:*** **:** ************:.** * :. : *: **:****: :*: * *:** ***:: :..**. *: * **:******** *:.*.: :.* **:** *:: . * * * * * :* : .* : *.:*", "identical_positions": 146, "similar_positions": 88, "identity": "35.87%" }, { "cls_id": "homologset.agr.MGI:2140779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIQ5-1", "uniprot_id": "SDA1_RAT", "id": "Q5XIQ5-1", "name": "Protein SDA1 homolog", "aln": "MSGRN-NNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNMEIFKLQ------------------------------PNKPSKELAELVMFMAQIGHCYPEHLSEFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSDLLELFFELLRCRD------------KLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTA-CFSKITKILVAALTFFLGKDEEEKQDSDSESEDDGPTARDLLVQYATG-KKGSKNKKKLEKAMKVLKKQKKK---KKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKER----FEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLLTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGK--------PTEASIEARIQEYGELDAKDYIPGAEVL-------ELEKEENTENDEDGWESASLS---------------EEEE-DGEWVDVHHS---------SDEEQQA----------------VAKKLDSMPM---EERKAKAAAVSTSRVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYLDMDSDEESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKTSRSFREKQLALRDALLKKRKRMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UZ2-1", "uniprot_id": "SDA1_MOUSE", "id": "Q80UZ2-1", "name": "Protein SDA1 homolog", "aln": "MSGRN-NNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNMEIFKLQ------------------------------PNKPSKELAELVMFMAQIGQCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHD------------KLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTA-CFSKITKILVAALTFFLGKDEEEKQDSDSESEDDGPTARDLLVQYATG-KKGSKNKKKLEKAMKVLKKQKKK---KKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKER----FEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLVTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGK--------PTEASIEARIQEYGELDAKDYIPGAEVL-------ELEKGENTEDDEDGWESASLS---------------EEEEEDGEWVDVHHS---------SDEEQQA----------------IATKLDSMPM---EERKAKAAAISTSRVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYLEIDSDEESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKSARSFRDKQLALRDALLKKRKRMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVU7-1", "uniprot_id": "SDA1_HUMAN", "id": "Q9NVU7-1", "name": "Protein SDA1 homolog", "aln": "MSNRN-NNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQ------------------------------PNKPSKELAELVMFMAQISHCYPEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELFRCHD------------KLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTA-CFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDGPTARDLLVQYATG-KKSSKNKKKLEKAMKVLKKQKKK---KKPEVFNFSAIHLIHDPQDFAEKLLKQLECCKER----FEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGK--------PTEASIEARVQEYGELDAKDYIPGAEVL-------EVEKEENAENDEDGWESTSLS---------------EEEDADGEWIDVQHS---------SDEEQQE----------------ISKKLNSMPM---EERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NV26-1", "uniprot_id": "SDA1_DANRE", "id": "Q6NV26-1", "name": "Protein SDA1 homolog", "aln": "MSGRH-NNKLPTNLPQLQNLIKRDPKSYTEEFLQQYRHYQSNVEIFKHQ------------------------------PDKANKDLSELVMFLAQVGHCYLEELSDFPQQLTDLLLNYHTVLESDLRMTFCKALIMLRNKDLVSPTSLLGLFFELLRCHD------------KLLRKTLYTHIVTDIKNINAKHKNNKMNTTLQNFMYTMLRDSNPIAAKISLDVMVELYRRNIWNDAKTVNVITTA-CFSKVTKILVAGLKFFLGKDEDEKKDDDSESEDEGSTARDLMMRYSTG-KKTSKNKKKLEKAMKVLKKHKKK---KKVEVFNFSAIHLIHDPQDFSEKLLKQLESSNER----FEVKIMMMELISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLCAAQSSHQLVPPEIIEPVIMTIANNFVTDRNSGEVMTVGINAIKEVVARCPLSMSEDLLQDLTQYKSHKDKNVVMSARGLIQLFRDLNPKMLTRKDRGR--------PTESSKEAKIHKYGELEAKDYIPGAEVL-------EAEKAEDEE-DEDGWESASMS---------------DDDE-DGEWVNVHHS---------SDDDQAE----------------VAEKLQSIPE---EERKAKAAMVSTSRLLTQDDFKKIRVAQMAKEVGNAPGKGQKRK--NVDSDEEERGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFTKKRGKLNPYASTSNKEKKRKKNFMMMRHSQNVRTKGKRSFREKQIALRDSLLKKRK-FK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KKH3-1", "uniprot_id": "SDA1_DROME", "id": "Q7KKH3-1", "name": "Protein SDA1 homolog", "aln": "MVRPN-NNQLPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALN------------------------------PSEENKSLDDIVMFVAQVAQCYPAVCEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLRCPD------------KNLRTFLQTHIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANPKAAKMSADIMIELYKKNIWNDSKTVNVIATVGCFSKVTKVLVTSLKFFLGHDEEDEEE-DTDSENEVDLKGALMANRVNK-KTKKRTKQLAQIKKQAVKAQKKK---KNAPAFNFSGIHLVHNPQGMAEGLFKQLQATNER----FEVKLMHLDVISRLIGIHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVMAIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGR--------QTEAQAERKVRAYGEREVHDTVLGAEALLKDSKTIDIESEDDTDSNDGEWVNVAHSDGEGGGADDDEEDEDEDEDDDDEDEDEENS---------NDEENEDEDNSDEGVESGEESAKAKKEKKDMRI---LNQKEAAQELALTRIFTDEDFKRINAANLKKTVTSAR----KR------PLEQDRAEFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKNFGMLRH--KARSKVKKSFKDKQQALRKHLLHQKK-MK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53313-1", "uniprot_id": "SDA1_YEAST", "id": "P53313-1", "name": "Protein SDA1", "aln": "MGRRSRAAMLPTNIILLQNLVKRDPESYQEEFLQQYAHYESLRDIFMLNGLAGGDSAAATNGLDVGNGSSTMAGTNGTTMSTSTSQLIELVGFVSQVCSCFPRETANFPSELKQLLLEHHKSLPFELKEKILSCLTMLRNKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLLKSCNTNGKNQKLNKSTQAVCFNLLDQPD-SQGIWATKLTRELWRRGIWDDSRTVEIMTQA-ALHQDVKIVMSGVMFFLDADREREENFEENSEDEDGFDLDALRHKMQVNKKTGRRGKKLENAIKTVKKKKKNGPGAPQGYLNFSAIHLLRDPQGFAEKLFKEHLSGKTKNKFDMEQKISLMQLLSRLIGTHKLIVLGIYTFFLKYLTPKQRDVTRIMSACAQACHDLVPPEVINVMVRKIADEFVSDGVANEVAAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKK--EHGEESENEDADANWEVDVDS---------------EEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMG----------IHKQDKREELVDASTLTGPIKYKQS-REERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** *: ****:**** :* :** ** *: * ::* : . ...* ::* *::*: *: :**..:.:** . * :: : ..* :****::: . .:: :* *: . . * **. : *:::: :*. *:: *: *:* * . :.:* :.: . : .: **:::.**:*::**:::: . .: : .*::::.: ***. *.: ::: : :**:: : . *. : : : :.:* :**: :***.***:::**.::* *:*: . : : :* *: ::::***:* *.*:::.:*.:. ::* *:**:**::: .**:.*.*** ::*: :: .:*::*::: :.:* : *:*: :*: *.**:: * *****. ** * *.* *:*: ** *:* * :* :* **: .:. : : :* : : : * * * : . .: : : * * :::: *.* . . .*::: : .. : : :: :*::* ** ::. . : : :: * *::. : * : :* ** .. *: .*..* : : : *.:*:**.: *** * : ..* * *:::** .** : :::* ", "identical_positions": 168, "similar_positions": 254, "identity": "21.08%" }, { "cls_id": "homologset.agr.MGI:2140796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09014-1", "uniprot_id": "S15A4_RAT", "id": "O09014-1", "name": "Solute carrier family 15 member 4", "aln": "------------------------------MEG------ERAPLLGSRR--AAAAAG-VFAGR---------------RAACGAVLLAELLERAAFYGVTANLVLFLNGAP-------FNWEGAQASQALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPRSRSFLCGDPHPELVRNCSAPFPNGTAVCPDAAARR---CAPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFLTGYLIPTVCVAIAFLVFLCGQSVFITKPPDGSAFTDMFRILTYSCCSQ-RGGQRRS-GEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLKIPEISSITTTHHT----LPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHGLLPSSLKRIAVGMFFVTCSAFAAGILESKRLDLVKEK-TINQTIGGVVYHAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSLKAIGWMSSHTDFGNINSCHLHYYFF--------LLAAIQGATLLLFLIVSVKYDR----QRARTDGGTASTRT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W98-1", "uniprot_id": "S15A4_MOUSE", "id": "Q91W98-1", "name": "Solute carrier family 15 member 4", "aln": "------------------------------MEG------ERAPLLGSRRPAVSAASA-VFAGR---------------RAACGAVLLAELLERAAFYGVTANLVLFLNGAP-------FDWEGAQASQALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGLLAFPLLAAPRSRSFLCGDPRPELVRNCSAPFPNGSASCPENAARR---CAPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFFTGYLIPTVCVAIAFLVFLCGQSVFITKPPDGSAFTDMFRILTYSCCSQ-RGGQRRS-GEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYALQSLHLKIPEISSITTTHHT----LPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLDLVKEK-TINQTIGGVVYHAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSLKAIGWMSSHTDFGNINSCHLHYYFF--------LLAAIQGATLLLFLIVSVKYDR----QRARTDGGPASTRT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N697-1", "uniprot_id": "S15A4_HUMAN", "id": "Q8N697-1", "name": "Solute carrier family 15 member 4", "aln": "------------------------------MEGSGGGAGERAPLLGARRAAAAAAAAGAFAGR---------------RAACGAVLLTELLERAAFYGITSNLVLFLNGAP-------FCWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPATRAALCG----------SARLLNCTAPGPDAAARC---CSPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFVTGYAIPTVCVGLAFVVFLCGQSVFITKPPDGSAFTDMFKILTYSCCSQKRSGERQSNGEGIGVFQQSSKQSLFDSCKMSHGGPFTEEKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNITTTPHT----LPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLNLVKEK-TINQTIGNVVYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGWMSSHTDFGNINGCYLNYYFF--------LLAAIQGATLLLFLIISVKYDHHRDHQRSRANGVPTSRRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ICA5-1", "uniprot_id": "A0A0R4ICA5_DANRE", "id": "A0A0R4ICA5-1", "name": "Solute carrier family 15 member 4", "aln": "------------------------------MAG--RDINESSPLL--ENSVTSTRSESVFNGR---------------RLACAAILLAESLERMAFYGITSNLVLFLNSSP-------FYWEGTLASQGPLIFMGVTYLISPFGGWLADAYLGKFLTIALSLGLYLLGMLLFPFVASDNTRNYLCGEEMAFPVQPAECFPENGTVPANVTCVNRPSYCRPAIYSGLVLVALGVGAVKSNITPFGADQVKDRGPEATRRFFNWFYWCINLGAIFSLGGIAYIQQNISFSIGYIIPAVCLGVSLIIFFLGKAVFITKPADGSAFSDMFRILGSALCGR--GPKEPS--------LLRPKPTVLDGAKVTYGGRFSDEKVEEVKSLVKILPVFLALIPYWTVYFQMQTTYYLQSLHLTIPGADPNSTDSHPNTFRFPAAWLTMFDAVLILMLIPLKDKVVDPILKRKGLLPSSLKRIAVGMFFVMCSAVAAGILETKRLDIVRTRGPIPQSLGGVIYYAADLPIWWQVPQYVLIGVSEIFASIAGLEFAYSAAPRSMQSAIMGLFFFFSGIGSFVGSGLLAIVSLKAIGWMSSHQDFGNINECRLNYYFF--------LLAAIQGITLLIFLIVSVKYDK----QKPKPASHRASMSNS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32901-1", "uniprot_id": "PTR2_YEAST", "id": "P32901-1", "name": "Peptide transporter PTR2", "aln": "MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVSDDVANSTERYNLSPSPEDEDFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAPFQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICCGTAIYIAGIFILFITSIPSVG---------------NRDSAIGGFIAAIILIGIATGMIKANLSVLIADQLPKRKPSIKVLKSGERVIVDSN-ITLQNVFMFFYFMINVG-SLSLMATTELEYHKGFWAAYLLPFCFFWIAVVTLIFGKKQYIQRPIGDKVIAKSFKVCWILTKNKFDFNAAKP------------------SVHPEKNYPWNDKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFITQASMMELHGIPN--------------DFLQAFDSIALIIFIPIFEKFVYPFIRRYTPLKP-ITKIFFGFMFGSFAMTWAAVLQS---FVYKAGPWYNEPLG--HNTPNHVHVCWQIPAYVLISFSEIFASITGLEYAYSKAPASMKSFIMSIFLLTNAFGSAIGCALSPVTVDPKFTWLFTGLAVACFISGCLFWLCFRKYNDTEEEMNAMDYEEEDEFDLNPISAPKANDIEILEPMESLRSTTKY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . .: * * * : :.* ** ::**::: : ::: .* : :. *: :* *: . ***::**: *: :* . .:*: *:: : : : . * : *: * . :: * : * . : :..* :**: **:* :** . : :: : .* .* :* . ::.: :: *: :* :* ....::. *:: .: . . : . :.:. *:::* : **: *** * * ::: *: : : :* **:: ::::**: :*.* *.::* * . :.:* .*::* : *.:*:: : : :.:* . .: : **:* *:**..*******:***:*** ** **:* **.:*:: ...** :*..* .:. : *: : .. : * : * : *:: * : .:. : : .. * ", "identical_positions": 104, "similar_positions": 176, "identity": "15.85%" }, { "cls_id": "homologset.agr.MGI:2140804", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCR2-1", "uniprot_id": "DHB13_MOUSE", "id": "Q8VCR2-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "--------------------------------------------------MNLILEFLLLVGVIIYSYLESLVKFFIPRRR---KSVTG-QTVLITGAGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKCRKLG-AVVHVFVVDCSNRAEIYNSVDQVKREVG-DVEIVVNNAGA-IYPADLLSAKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLG----KTGIQTSCLCPVFVN-TGFTKNPSTR--LWPVLEPEEVARSLINGILTNKKMIFVPSYINISLILEKG-PGFSSKHPHGGSQ-------------QPVTPIPGDLTPSSDFLKH------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M875-1", "uniprot_id": "DHB13_RAT", "id": "Q5M875-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "--------------------------------------------------MNLILELLLLVGIIIYSYLESLVKFFIPQRR---KSVAG-QTVLITGAGHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKCRKLG-AVVHVFVVDCSNRAEIYKSVDQVKKEVG-DIEIVVNNAGA-IYPADLLSTKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAELDTLG----KTGIKTSCLCPVFVN-TGFTKNPSTR--LWPVLEPDEVARSLIDGILTNKKMIFVPSYINISLIVEMFFPERVLKAINRIQN-------------IQFEAIVGHRTKRK-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z5P4-1", "uniprot_id": "DHB13_HUMAN", "id": "Q7Z5P4-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "--------------------------------------------------MNIILEILLLLITIIYSYLESLVKFFIPQRR---KSVAG-EIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG-VTAHAYVVDCSNREEIYRSLNQVKKEVG-DVTIVVNNAGT-VYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALG----KTGIKTSCLCPVFVN-TGFTKNPSTR--LWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQN-------------IQFEAVVGHKIKMK-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR28-1", "uniprot_id": "Q9VR28_DROME", "id": "Q9VR28-1", "name": "Short-chain dehydrogenase/reductase family 16C member 6", "aln": "------------------MTASP---GLLHMD------------QPLRAIYQFLLDLLVFTIKSVYYVLESIYYSLLPQRFRKLKDISG-QVVLITGGGGGVGRLIALNFARLQARIVIWDINQEAIKTTVDLLAKHGYDNCKGYVVDISDREQIYQRASQVTEEVG-PVDILINNAGI-VCCKPFWELHDRVIQNTYNINIISHYWTVKAFLPHMMRNNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHG----YDQIQMSLICPYYIN-TGMFSGVRPR--MMPMLEPQYVADRIENAVRCNEVWCVLPNSIRLLTPLKCLLPAKMCWELMSRVIRGPE----------SMMMFQGRGRVAAG----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIG6-1", "uniprot_id": "Q9VIG6_DROME", "id": "Q9VIG6-1", "name": "", "aln": "MEKNNNELSAEDAQILANGHAHPNANGVVHQKTEPVAPAADGWRQVLWNTWDAFADVAWFIICCIGYILQDLYYIAFGYPE---KELNT-DIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEEAG-GYCKGYVVDISKKEEVYKAADVIRDEVG-DITLLINNAGV-VSGLHLLDTPDHLIERSFNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLG----HTNIRTTCICPFFIQATGMFDDVNAR--WVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLLSFKWTFPWGCVGGLLKRLVPDASPHGLPSSIAVPTVPLNSNSKLTAADIAALDAELSSVTLPAKPPSMLIQRTPSLGERVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07530-1", "uniprot_id": "YD114_YEAST", "id": "Q07530-1", "name": "Uncharacterized oxidoreductase YDL114W", "aln": "----------------------------------------------------MVRKNKINRASGTTKHLKDFPSVILSLPSYNPSILSKNATALITGGSSGLGFELAKELSRRINKVIVADIQS------FPTFAQVEYNNIFYYQCDITSLDEIKNLKKAIERDHG-NINIIINNAGV-AHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVCPGKIKTNMFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKTLSWPYRHLLKHFSG-------------MDHVTSTSPRAINPKRSA-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06417-1", "uniprot_id": "TDA5_YEAST", "id": "Q06417-1", "name": "Uncharacterized oxidoreductase TDA5", "aln": "---------------MNIDCLCRWVVLPLLRYPLLVALVLRWSLSDSISICLTIYTLLINAFLIANSYIKRSGQVAWKSLR----EFKN-GIVLITGGSKGLGRAIVSQLLQDYSNLTILNVDICP--------SSVRNTRVKDLICDLSDDEEVAALLNLLKRKYKNEIRLIVNNAGVRANFTGFNGMERDNLDKIFKINTFAPLQFIQELAPSRHSTRQCYIVNIASILGILTPAKVAAYAASKAALIAFHQSYSFELQNEG----VRNIRTLLVTPGQLNTEMFAGFKPPRQFFAPVIDITTLAAKIVRYCELGQRGQLNEPFYCSFAHLLMCVPYSLQRIVRSFSR-------------IDCCLPDE-----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . .****.. *:* . .: : : : ::. . * :. :: . : . : :::**** : : . .:* :. . : .* .:.*: * * ::* * :.*.. .: . *: : * :: : . * : :. : .. . . . ", "identical_positions": 22, "similar_positions": 67, "identity": "5.34%" }, { "cls_id": "homologset.agr.MGI:2140839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498T9-1", "uniprot_id": "LRC8C_RAT", "id": "Q498T9-1", "name": "Volume-regulated anion channel subunit LRRC8C", "aln": "MIPVTEFRQFSEQQPAFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVQPAQNHSSLSNVSQTVINTTPLPPPKPSPTNPATVEMKGLKTDLDLQQYSFINQMCYERALHWYAKYFPYLVLIHTLVFMLCSNFWFKFPGSSSKIEHFISILGKCFDSPWTTRALSEVSGEDSEEKDNRKNNMNRSNTIQSGPEGSLVKSQSLKSIPEKFVVDKSTAGALDKKEGEQAKALFEKVKKFRLHVEEGDILYAMYVRQTVLKVIKFLIIIAYNSALVSKVQFTVDCNVDIQDMTGYKNFSCNHTMAHLFSKLSFCYLCFVSIYGLTCLYTLYWLFYRSLREYSFEYVRQETGIDDIPDVKNDFAFMLHMIDQYDPLYSKRFAVFLSEVSENKLKQLNLNNEWTPDKLRQKLQTNAHNRLELPLIMLSGLPDTVFEITELQSLKLEIIKNVMIPATIAQLDNLQELSLHQCSVKIHSAALSFLKENLKVLSVKFDDMRELPPWMYGLRNLEELYLVGSLSHDISKNVTLESLRDLKSLKILSIKSNVSKIPQAVVDVSSHLQKMCIHNDGTKLVMLNNLKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYNSIAYIPEHIKKLTSLERLFFSHNKVEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDIKGNHFEVLPPELGDCRALKRAGLVVEDALFETLPSDVREQMKAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R502-1", "uniprot_id": "LRC8C_MOUSE", "id": "Q8R502-1", "name": "Volume-regulated anion channel subunit LRRC8C", "aln": "MIPVTEFRQFSEQQPAFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVQPAQNHSSVPNVSQAVISTTPLPPPKPSPTNPATVEMKGLKTDLDLQQYSFINQMCYERALHWYAKYFPYLVLIHTLVFMLCSNFWFKFPGSSSKIEHFISILGKCFDSPWTTRALSEVSGEDSEEKDNRKNNMNRSGTIQSGPEGNLVRSQSLKSIPEKFVVDKSAAGALDKKEGEQAKALFEKVKKFRLHVEEGDILYAMYVRQTVLKVIKFLIIIAYNSALVSKVQFTVDCNVDIQDMTGYKNFSCNHTMAHLFSKLSFCYLCFVSIYGLTCLYTLYWLFYRSLREYSFEYVRQETGIDDIPDVKNDFAFMLHMIDQYDPLYSKRFAVFLSEVSENKLKQLNLNNEWTPDKLRQKLQTNAHNRLELPLIMLSGLPDTVFEITELQSLKLEIIKNVMIPATIAQLDNLQELCLHQCSVKIHSAALSFLKENLKVLSVKFDDMRELPPWMYGLRNLEELYLVGSLSHDISKNVTLESLRDLKSLKILSIKSNVSKIPQAVVDVSSHLQKMCVHNDGTKLVMLNNLKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYNSIAYIPEHIKKLTSLERLFFSHNKVEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDIKGNHFEVLPPELGDCRALKRAGLVVEDALFETLPSDVREQMKAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDW0-1", "uniprot_id": "LRC8C_HUMAN", "id": "Q8TDW0-1", "name": "Volume-regulated anion channel subunit LRRC8C", "aln": "MIPVTEFRQFSEQQPAFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVQPAQNHSSLSNVSQAVASTTPLPPPKPSPANPITVEMKGLKTDLDLQQYSFINQMCYERALHWYAKYFPYLVLIHTLVFMLCSNFWFKFPGSSSKIEHFISILGKCFDSPWTTRALSEVSGEDSEEKDNRKNNMNRSNTIQSGPEDSLVNSQSLKSIPEKFVVDKSTAGALDKKEGEQAKALFEKVKKFRLHVEEGDILYAMYVRQTVLKVIKFLIIIAYNSALVSKVQFTVDCNVDIQDMTGYKNFSCNHTMAHLFSKLSFCYLCFVSIYGLTCLYTLYWLFYRSLREYSFEYVRQETGIDDIPDVKNDFAFMLHMIDQYDPLYSKRFAVFLSEVSENKLKQLNLNNEWTPDKLRQKLQTNAHNRLELPLIMLSGLPDTVFEITELQSLKLEIIKNVMIPATIAQLDNLQELSLHQCSVKIHSAALSFLKENLKVLSVKFDDMRELPPWMYGLRNLEELYLVGSLSHDISRNVTLESLRDLKSLKILSIKSNVSKIPQAVVDVSSHLQKMCIHNDGTKLVMLNNLKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDVREQMKTE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************************************************************:.****:* .***********:** ********************************************************************************************************.*******..**.****************:******************************************************************************************************************************************************************************************************************************************************.*********************************************************:****************************************:*************************************************************************:***:*************** *****:**************************************************************************************:******:***********************************::", "identical_positions": 780, "similar_positions": 20, "identity": "97.14%" }, { "cls_id": "homologset.agr.MGI:2140843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHY2-1", "uniprot_id": "NOC4L_MOUSE", "id": "Q8BHY2-1", "name": "Nucleolar complex protein 4 homolog", "aln": "----------MERHPASASSRQELGRLLEAVLTSRGQANAVFDILAVLQ-SEEPEEIEEGVRTCSRLFGTLLEREELFVGSLPSEDTALAGSQGATYKYKVWIRHRYHSCCNRLEELLAHPTFQVKELALKTLMKFVQLEGAKPLEKPQWESHYLFPRTLFRAVVGGLLTP-----EDDHSLLISHFCEYLEYDDIRYHTMQVATSIMARATSQ---QPEVSLTLWNNAFTLLSAVSLPLQECELTNFYVKHAQTSDKWKVVHLKEHKKAFQEMWLGFLK--HKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVG------GAISLLALNGLFILIHKHNLEYPDFYQKLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGP-----------------ELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSKAASVINQVLSVPEVSIAPLLELTAYEIFEQDLKKKMPESVPLEFIPAKGLLGRQDDLCTQFFCLS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0I8-1", "uniprot_id": "NOC4L_RAT", "id": "Q5I0I8-1", "name": "Nucleolar complex protein 4 homolog", "aln": "----------MERQPASTGSRQELGRLLEAVLSNRGRANAVFDILAVLQ-SEDPEEIKEGVRTCSRLFGTLLEREELFVGSLPCEDMALAGSQGATYKYKVWMRHRYHSCCNRLEELLTHPSFQVKELALETLMKFVQLEGAKPLEKPQWESHYLFPRTLFRAVVGGLLTP-----EDDHSLLISQFCEYLEYDDIRYHAMQVATSILARATSR---QPEVSLTFWNNAFTLLSAVNLPLQEHELTNFYVKHAQTSSKWKVVHLKEQRKAFQEMWLGFLK--HKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVG------GAISLLALNGLFILIHKHNLEYPDFYQRLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGP-----------------ELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSRAASVINQALSVPEVSIAPLLELTAYEIFEQDLKKMMPESVPLEFIPAKGLLGRQDDLCTQFFCLS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BVI4-1", "uniprot_id": "NOC4L_HUMAN", "id": "Q9BVI4-1", "name": "Nucleolar complex protein 4 homolog", "aln": "----------MEREPGAAGVRRALGRRLEAVLASRSEANAVFDILAVLQ-SEDQEEIQEAVRTCSRLFGALLERGELFVGQLPSEEMVMTGSQGATRKYKVWMRHRYHSCCNRLGELLGHPSFQVKELALSALLKFVQLEGAHPLEKSKWEGNYLFPRELFKLVVGGLLSP-----EEDQSLLLSQFREYLDYDDTRYHTMQAAVDAVARVTGQ---HPEVPPAFWNNAFTLLSAVSLPRREPTVSSFYVKRAELWDTWKVAHLKEHRRVFQAMWLSFLK--HKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDLG------GALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGP-----------------ELDADPYDPGEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPEVSIAPLLELTAYEIFERDLKKKGPEPVPLEFIPAQGLLGRPGELCAQHFTLS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBT2-1", "uniprot_id": "NOC4L_DANRE", "id": "Q4VBT2-1", "name": "Nucleolar complex protein 4 homolog", "aln": "--MAPSGDSNVKEHNNQVSYKKAINTKTDLILQNKKHANDIFDVIEYLQ-SEKEKEIIFATNACSKIFCELIERGDLFVGELPKEEDLAQGDRSAEEKYHIFMRHRYNSCVELMLENVSHESFQVKETSLCAVMKFVATEGKHPLQNLDWSEHYNFPRELIQALVEHLLSE-----KEDMSLLISRFQEFMEKDDVRYYVMSSVRYSTATVMERN--KKAVIPVFQNNVFNLLTTINIPNQASEMTNFLVQQQSKHDDWKAAKLKEHKRAFEQMWLLFLR--YKLPGSMYKKILVILHESILPQMSDPKLMMDFLSAAYDIG------GAISLSALNGLFVPIHEHNLDYPDFYKKLYNLLDPSIFHVKYRARFFHLANIFLSSTHLPVYLVAAFVKRLARLSLTAPPTALLILLPFICNLIRRHPSCRVLIHRPSAAD----------------EPCDDPYVMEEEDPAQCHALESSLWEIKTLQNHHHPDVSKAATMINEPLSAQEEDISELLELTTFELMERELKGE-KKTVPLEFDMATDLLKSSREVLGVHFTLE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06512-1", "uniprot_id": "NOC4_YEAST", "id": "Q06512-1", "name": "Nucleolar complex protein 4", "aln": "MVLLISEIKDIAKRLTAAGDRKQYNSIIKLINELVIPEN----VTQLEE-DETEKNLRFLVMSLFQIFRKLFSRGDLTLPSSKK-------STLEKEQFVNWCRKVYEAFKTKLLAIISDIPFET-SLGLDSLDVYLQLAELESTHFASEKGAPFFPNKTFRKLIIALWSSNMGEIEDVKSSGASENLIIVEFTEKYYTKFADIQYYFQSEFNQLLEDPAYQDLLLKNVGKWLALVNHDKHCSSVDADLEIFVP-NPPQAIENESKFKSNFEKNWLSLLN--GQLSLQQYKSILLILHKRIIPHFHTPTKLMDFLTDSYNLQSSNKNAGVVPILALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFFRLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKHPNCMIMLHNPAFISNPFQTPDQVANLKTLKENYVDPFDVHESDPELTHALDSSLWELASLMEHYHPNVATLAKIFAQPFKKLSYNMEDFLDWNYDSLLNAESSRKLKTLPTLEFEAFTNVFDNEDGDSEASSQGNVYLPGVAW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W4R1-1", "uniprot_id": "Q9W4R1_DROME", "id": "Q9W4R1-1", "name": "CCAAT-binding factor domain-containing protein", "aln": "--MKPLTVKVNDDTGKSLAKKKLQSKANSLLNAEQVDIKTLKGFVQLLKNTPDNMPAGEVMNTLEVIFKNLLKRKAIDG----------------TEKQGLKIKKLYEETWLLLIENLLVDSQCS--VAVKVCMQLIKVEAKHPIAPNKG-----WPTYWIRGMLETLINS-----DTTPTTALANYGKYCKNLDVLEITLTQLKSLVPDEDFKD------SPIKAMNFLSIVNLLDMGKSVLSTADYHVESAKKQTFNYELN----RKRLNNLWATIMAKGNEVDEKLHRQILVVLLERVINHLNDPIQLTDFLMDSLHQFD-----GPIALLALQGIFTLMQKQNITYPDVYEKLYNMFYPRMFHNKYKARLFYLADIFLTSTHLPENLVAAFVKRLARLALQSPTEDAVIMIRFVCNLLLRHTGLQKLIRASHAV-----------------DEVSDPYNQTETDPVKSEAINSSLWEITLLQKHVVPEVANAARFINSSLPVMEFDLAPLLDRKECNIFDDELQSKAKQFA-LNYERPTNLALPKNQFVTKYWDLI--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . . : : . : : :* *:.* : : :: *. : : . .: : .. . :* :: :: * . . : :. . : : : * . : :. : : :: * :: :: . ::.:*: : . :: :: * : *** : . * :.: **:*:* ::. *: **:.* :** :: * ::* **:**:* * ::**:*:**. ***:* *:****:* :*. : :: :: **: :*. ::: . : **: * ** .*::*.***: * .* *:*: * .: . : . .: :*: . .::: : . *:: .: ", "identical_positions": 68, "similar_positions": 138, "identity": "11.97%" }, { "cls_id": "homologset.agr.MGI:2140844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V660-1", "uniprot_id": "G3V660_RAT", "id": "G3V660-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYATAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQE--RPGQAHQVPRFVRVNTLKTCPEDAIDYFKRQGFSYQGR------ASSLEDLRTLKGQHFLLDPLLPELLVFPAQTD--LHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLK------NQGKIFAFDQDAKRLAAMATLLARAGVSCCEVAEKDFLTVSPSDQRYGQVQYILLDPSCSGSGMLSRQLEEHGEGTPSK-----------------------ERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQ---QNSGTFRLAP---VLPTWPHRG-LSTFPGS-------------EHCLRASPETTLTGGFFIAVFERAEVVPSPAPQTSAVVPEPLSKAPKRKRRR----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4F6-1", "uniprot_id": "NSUN5_MOUSE", "id": "Q8K4F6-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYAAAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQVPRFVRVNTLKTRPEDAIDYFKRQGFSYQGR------ASSLEDLRALKGQHFLLDPLLPELLVFPAQTD--LHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLK------NQGKIFAFDQDAKRLAAMATLVARAGVSCCELAEKDFLTVSPSDQRYSQVQYILLDPSCSGSGMLSRQLEEHGEGTPSK-----------------------ERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQ---HNSGTFRLAP---VLPTWPHRG-LSTFPGS-------------EHCLRASPETTLTGGFFIAVFERAEVVPTPAPQTDAMDPEPLSQVPKRKRRRKAAVGASMQPST----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P11-1", "uniprot_id": "NSUN5_HUMAN", "id": "Q96P11-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYAAAAGVLAGVESRQGSIKGLVYSSNFQNVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFSYQGR------ASSLDDLRALKGKHFLLDPLMPELLVFPAQTD--LHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLK------NQGKIFAFDLDAKRLASMATLLARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGMPSRQLEEPGAGTPSP-----------------------VRLHALAGFQQRALCHAL-TFPSLQRLVYSTCSLCQEENEDVVRDALQ---QNPGAFRLAP---ALPAWPHRG-LSTFPGA-------------EHCLRASPETTLSSGFFVAVIERVEVPR----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63ZY6-1", "uniprot_id": "NSN5C_HUMAN", "id": "Q63ZY6-1", "name": "Putative methyltransferase NSUN5C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPELLVFPAQTD--LHEHPLYRAGHLILQDRASCLPAMLLDPRQAPMSWMPVPPQAIKTSHLAALLK------NQGKIFAFDLDARRLASMATLLAWAGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPSCSGSGMPSRQLEEPGAGTPSP-----------------------VRLHALAGFQQRALCHAL-TFPSLQRLVYSMCSLCQEENEDMVQDALQ---QNPGAFRLAP---ALPARPHRG-LSTFPGA-------------EHCLRASPKTTLSGGFFVAVIERVEMPTSASQAKASAPERTPSPAPKRKKRAKSCSRCLHTALHIAEAPGSLLPGGKGRCLSSPWKTLGPHRRQQFAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BD27-1", "uniprot_id": "A0A8M3BD27_DANRE", "id": "A0A8M3BD27-1", "name": "", "aln": "-----------MALYLKAAEILEKVEQKRGAVKTLVYDSKFPNIKQLFALVCETQKYSSVLQEIINSTKLLK-ETKLR------IHLAKVLVYDLLIGH--GVKCGG-AWKTTMLKHRARLQAALARIKIKRKVSRNQDLLPSSIQQTQNDVIPRYVRVNTLKTSLEDVIDYLKREGFSYQGT------PGRLEDLDRLSGKMFLCDLHLKDLLVFSGKTD--FHDHFLYKAGHIILQGKASCLPAFLLNPPVGSHVIDACAAPGNKTSHLAAIMK------NKGKLFAFDLDAKRLSTMSTLLLRAGVTCHKLANQDFLKVDPQNSEYKEVKYILLDPSCSGSGMVCLRDELP--ETQED-----------------------GRLQALAAFQLHCLNHAL-QFPQLERIVYSTCSIHSQENEEVVTACLQ---RNPG-FRLVH---LLPDWPERG-HEPLT----------------QCLRASTAKTRTHGFFVAMLERRPAQSDKETPPLNTPLSSASQEKQDKPQSNPSDEEQENMETSNEQPANPSSKKKRK------RNRKKHKKQES--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDZ4-1", "uniprot_id": "NSUN5_DROME", "id": "Q9VDZ4-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-MSKKPHSIKVPTQYRATAKILKAALEQQKCIKTLIFAEKHARTRSLHTVLKKFSENRVALEKAIEETGLLRDNPSFD------PSLAKILVTELLFGR--KELNGESKPVQTVRSYKDRLLNSIRDFGVQRKEPN-----------------PRYVRINTNLYSLAEALDYLHKSDWRRKELPADASYADFLTAIKSLAENEFMTDLHVEGVLIFPAKWSNYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHICNVMQ------NKGCIYSVEQDHVRYNTLCEITKDAGCDIVKPILGDALNLTP--ERFPDVEYILVDPSCSGSGMQNR--MTVCDEPKED-----------------------KRLQKLQGLQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVVQRCLQ---LNPSFKLLSCKKALRNKWHNVG-DKDYPNIG------------KNVLYCQPDSDLTDGIFLALFEKRREGEKD--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53972-1", "uniprot_id": "RCM1_YEAST", "id": "P53972-1", "name": "25S rRNA (cytosine(2278)-C(5))-methyltransferase", "aln": "MNFYRDATWVLEDIEKEAAKERISGSMQTLVLKSCKRYKLKSNPKHIYAVLDSCWKYKPYLEKVMKKAHILEDIPKKKGKPLFSRLTLLLLCHDLLLSKQKRIQMGKHPIKDYVLKFKSPLHSEMVKLKLKLKVRELSELVLS-EDISNDLPPVRWIRINPLKCHPNGETEPVLAELRKKFTL--------KVDKWSELVPGSIYYDEFIPNLFGIHPSDK--ITAHELYKHGKIIIQDRASCFPAHILNPGPSDIVIDSCSAPGNKTTHTASYIYPEPPKDNNTRIYAFEKDPERAKVLQKMIKIAGCSPNISVNVGDFTKLATPEKYKDVTCFIVDPSCSGSGIFGRKFFDSFNRRKIDDKDDDGGIVPDEQEEFIAKEELQTRLAKLSSFQFQMVKHAM-SFPAAKKIVYSTCSIHAEENERVVIDLLLDKSVREWGWKVAPKREVIPSWPRRGKVEEFEEVFRDGVTYDPQQLAEGCIRALPKSDGGIGFFAVCFERD--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : . . * * : ::*:*.:*:*:.* :* * . .. . ** : . : *: :::.: * * : : ** . : . .: :* .::********: ** * .:* : : **: ** :::.*. **: :*** :* * . : . * . : . . . *:* . :*: ", "identical_positions": 45, "similar_positions": 66, "identity": "7.81%" }, { "cls_id": "homologset.agr.MGI:2140872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1B7-1", "uniprot_id": "A0A0G2K1B7_RAT", "id": "A0A0G2K1B7-1", "name": "", "aln": "MRQSFGRGLSFHSDCRETSHCVPGARPLPSGRAAEGSGELERALGAASPTLPPAVSAPASQVETPPPAVRGAGEEGLGSERPPLHLSHGRRVTKTTALAKTVTSGREPRALAGSPLPMEDSFLESFGRLSLQ---QRQQQPPPRPLPARGPPPRRHSFRKHLYLLRGLPGSGKTTLARQLQRDYPRALIFSTDDFFFREDGTYEFNPIFLEEAHEWNQKRARKAMRSGTSPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVPKEKIQRMKERYEHNVTFHSVLHAEKPSRANRNQDRDSA-PSGGSGYWNTSSELPNQRARGNSSNES--YRRGGYHHGY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V2Q8-1", "uniprot_id": "N42L1_MOUSE", "id": "Q3V2Q8-1", "name": "NEDD4-binding protein 2-like 1", "aln": "---------------------------------------------------------------------------------------------------------------------MEDSFLESFGRLSLQ---QRQQQPPPRPPPARGPPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDYPRALIFSTDDFFFKEDGTYEFNPNLLEEAHEWNQRRARKAMRNGISPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVPKEKIQRMKERYEHNVTFHSVLHAEKPSRANRNQGRNSE-PSSGSGYWNTYTELPNRRANGLYSNEG--YRRGGHHQGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TBK1-1", "uniprot_id": "N42L1_HUMAN", "id": "Q5TBK1-1", "name": "NEDD4-binding protein 2-like 1", "aln": "---------------------------------------------------------------------------------------------------------------------MEDSFLQSFGRLSLQPQQQQQRQRPPRP-PPRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVSREKIHRMKERYEHDVTFHSVLHAEKPSRMNRNQDRNNALPSNNARYWNSYTEFPNRRAHGGFTNESSYHRRGGCHHGY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:******** *:*:* **** *.**.******************************:*:*************:***:***** :*********:*******.* *****************************************************.:***:********:************** ****.*:. **..: ***: :*:**:**.* :**. :**** *:**", "identical_positions": 196, "similar_positions": 31, "identity": "54.29%" }, { "cls_id": "homologset.agr.MGI:2140873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZTF5-1", "uniprot_id": "A0A8I5ZTF5_RAT", "id": "A0A8I5ZTF5-1", "name": "Tetratricopeptide repeat protein 28", "aln": "MEQPPPLAPEPAS----ARSRRRREPESPP--APIPLFGAKTIIQR---------SPDEPALSKAEFVEKVRQSNQACHDGDFHTAIALYNEALAVDPQNCILYSNRSAAYMKTQQYHKALDDAVKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDTLEPTYQQLQKMKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAHWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREETSTATSSQPHTGRGEMPQGLPFAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDDLSEARELGNMGAVYIAMGDFENAVQCHEQHLRIAKDLGSKREEARAYSNLGSAYHYRRNFDKAMSYHNCVLELAQELTEKPIEMRAYAGLGHAARCMQDLERARQYHEQQLSIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFTKAEECQKYLLSLAQSLDNSQAKFRALGNLGDIFVCKKDVNGAIKFYEQQLGLSHHVKDRRLEASAYAALGTAYRMVQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYQEQLELGRKLKEPSLEAQVYGNMGITKMNMNVVEDAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRATGSLQQALVCFEKRLVVAHELGEASNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETDNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLVAKTLSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAFADLLVERQTGQQDSDPYSPITIDQILEMVNAQRGLVLYYSLAAGYLYSWLLAPGAGILKFHEHYLGDNSVES------------------------SSDFQAGSSAALPIATSSTLEQHIASVREALGVESYYSRACASSETESEAGDIVEQQLEEMNKQLNSVTDPTGFLRMVRHNNLLHRSCQSMTSLFSG-----TVSPSKDGTSSLPRRQNSLAKPP--------LRALYDLLIAPMEGGLMHSSGPVGR--HRQLVLVLEGELYLVPFALLKGSASN-EYLYERFTLIAVPAVRSLGPHSKGHLRKTPPTYSSSTAMAAVIGNPKLPSAVMDRWLWG--PMPSAEEEAYMVSELLGCQPLVGSMATKERVMSALTQAECIHFATHVSWKLSALVLTPNTEGNPASSKSSFGHPYTIPESLRVQDDASDVESISDCPPLRELLLTAADLLDLRLSVKLVVLSSSQEANSRVTADGLVALTRAFLAAGAQCVLVALWPVPVAASKMFVHAFYSSLLNGLKASASLGEAMKAVQSSKAFSHPSNWAGFTLIGNDIKLNSPSSLIGQALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPAASGLPAAVFFPTSDPGDRLQQCSSTLQALLGLPNPALQALCKLITASETG-EQLISRAVKNMVGMLHQVLVQLQACEKEQDFASAP--IPVSLSVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGKQASRRTTHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNTLPLGYQHPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPEGG-LEGGAPRGRQDYDRSKSTHPQRATLPRRQMSPQARRGVSKEEEEYEGFSIISMEPLATYQGEGKARFSP-----DPKQPCVKAPGGVRLSVSSKGSVSTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEESSPKLDP----------QELAQRILEETKSHLLAVERLQRSGGPASP--DREDGVVAPSSTTVFRASETSAFSKPILSHQRSQLSPLTIKP------QPPARSSSLPKVSS----PATSEVSGKDGLSPPGSSHPSPGR-----DTPVSPADPPLFRLKYPSSPYSAHISKSPRNTSP-------ACSAPSPALSYSSAGSARSSPADVP----------DEKVQAVHSLKMLWQSTPQPPRGPRKICRGAPGTLTSKRDVLS--LLNLSPRHGKEEGEADRLELKELSVQRRDEVPPKVPTNGHWCSDAATLTTASGRS--TTAAASRPLRLPLANGYKFLPPGRLFPSSKC-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XJ3-1", "uniprot_id": "TTC28_MOUSE", "id": "Q80XJ3-1", "name": "Tetratricopeptide repeat protein 28", "aln": "MEQPPPLAPEPAS----ARSRRRREPESPP--APIPLFGARTVVQR---------SPDEPALSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKTQQYHKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDTLEPTYQQLQKMKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAHWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDRE-----------------------AASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDDLSEARELGNMGAVYIAMGDFENAVQCHEQHLRIAKDLGSKREEARAYSNLGSAYHYRRNFDKAMSYHNCVLELAQELMEKPIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFAKAEECQKYLLSLAQSLDNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLSHHVKDRRLEASAYAALGTAYRMVQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYQEQLELGRKLKEPSLEAQVYGNMGITKMNMNVMEDAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRATGSLQQALVCFEKRLVVAHELGEASNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETDNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLVAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAFADLLVERQTGQQDSDPYSPITIDQILEMVNAQRGLVLYYSLAAGYLYSWLLAPGAGILKFHEHYLGDNSVES------------------------SSDFQAGSSAALPVATNSTLEQHIASVREALGVESYYSRACASSETESEAGDIMEQQLEEMNKQLNSVTDPTGFLRMVRHNNLLHRSCQSMTSLFSG-----TVSPSKDGTSSLPRRQNSLAKPP--------LRALYDLLIAPMEGGLMHSSGPVGR--HRQLVLVLEGELYFVPFALLKGSASN-EYLYERFTLIAVPAVRSLGPHSKCHLRKTPPTYSSSTTMAAVIGNPKLPSAVMDRWLWG--PMPSAEEEAFMVSELLGCQPLVGSMATKERVMSALTQAECVHFATHVSWKLSALVLTPNTEGNPAGSKSSFGHPYTIPESLRVQDDASDVESISDCPPLRELLLTAADLLDLRLSVKLVVLSSSQEANGRVTADGLVALTRAFLAAGAQCVLVALWPVPVAASKMFVHAFYSSLLNGLKASASLGEAMKVVQSSKAFSHPSNWAGFTLIGSDVKLNSPSSLIGQALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPAASGLPAAVFFPTSDPGDRLQQCSSTLQALLGLPNPALQALCKLITASETG-EQLISRAVKNMVGMLHQVLVQLQACEKEQDFASAP--IPVSLSVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGKQASRRTTHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQHPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPEGG-LEGGGPRGRQDYDRSKSTHPQRATLPRRQTSPQARRGASKEEEEYEGFSIISMEPLATYQGEGKTRFSP-----DPKQPCVKAPGGVRLSVSSKGSVSTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEESTPKLDP----------QELAQRILEETKSHLLAVERLQRSGGPAGP--DREDSVVAPSSTTVFRASETSAFSKPILSHQRSQLSPLTVKP------QPPARSSSLPKVSS----PATSEVSGKDGLSPPGSSHPSPGR-----DTPVSPADPPLFRLKYPSSPYSAHISKSPRNTSP-------ACSAPSPALSYSSAGSARSSPADAP----------DEKVQAVHSLKMLWQSTPQPPRGPRKTCRGAPGTLTSKRDVLS--LLNLSPRHGKEEGGADRLELKELSVQRHDEVPPKVPTNGHWCTDTATLTTAGGRS--TTAAP-RPLRLPLANGYKFLSPGRLFPSSKC-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AY4-1", "uniprot_id": "TTC28_HUMAN", "id": "Q96AY4-1", "name": "Tetratricopeptide repeat protein 28", "aln": "MEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQR---------SPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDSLEPTYQQLQKMKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDRE-----------------------AASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAFADLLVERQTGQQDSDPYSPVTIDQILEMVNGQRGLVLYYSLAAGYLYSWLLAPGAGIVKFHEHYLGENTVEN------------------------SSDFQASSSVTLPTATGSALEQHIASVREALGVESHYSRACASSETESEAGDIMDQQFEEMNNKLNSVTDPTGFLRMVRRNNLFNRSCQSMTSLFSN-----TVSPTQDGTSSLPRRQSSFAKPP--------LRALYDLLIAPMEGGLMHSSGPVGR--HRQLILVLEGELYLIPFALLKGSSSN-EYLYERFGLLAVPSIRSLSVQSKSHLRKNPPTYSSSTSMAAVIGNPKLPSAVMDRWLWG--PMPSAEEEAYMVSELLGCQPLVGSVATKERVMSALTQAECVHFATHISWKLSALVLTPSMDGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPPLQELLLTAADVLDLQLPVKLVVLGSSQESNSKVTADGVIALTRAFLAAGAQCVLVSLWPVPVAASKMFIHAFYSSLLNGLKASAALGEAMKVVQSSKAFSHPSNWAGFMLIGSDVKLNSPSSLIGQALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPPTSGLPAAVFFPTSDPGDRLQQCSSTLQSLLGLPNPALQALCKLITASETG-EQLISRAVKNMVGMLHQVLVQLQAGEKEQDLASAP--IQVSISVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGKQANRRTVHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQQPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPEGG-SEGGGPGGRQDHDRSKNAYLQRSTLPRSQLPPQTRPAGNKDEEEYEGFSIISNEPLATYQENRNTCFSP-----DHKQPQPGTAGGMRVSVSSKGSISTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEESNPKLDP----------QELAQKILEETQSHLIAVERLQRSGGQVSKSNNPEDGVQAPSSTAVFRASETSAFSRPVLSHQKSQPSPVTVKP------KPPARSSSLPKVSSGYSSPTTSEMSIKDSPSQ-HSGRPSPGC-----DSQTSQLDQPLFKLKYPSSPYSAHISKSPRNMSPSSGHQSPAGSAPSPALSYSSAGSARSSPADAPDIDKLKMAAIDEKVQAVHNLKMFWQSTPQHSTGPMKIFRGAPGTMTSKRDVLS--LLNLSPRHNKKEEGVDKLELKELSLQQHDGAPPKAPPNGHWRTETTSLGSLPLPAGPPATAPARPLRLPSGNGYKFLSPGRFFPSSKC-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSK6-1", "uniprot_id": "Q9VSK6_DROME", "id": "Q9VSK6-1", "name": "Tetratricopeptide repeat protein 28", "aln": "MTNYENIINLPLN--FNANNHAAGNNENNAKIAIVGEQLLNKMSQRDFSENEPECTPELPAANRALFLEKVRQSNAACQSGDFATAVLLYTDALQLDPGNHILYSNRSAALLKQGQFTAALQDATQARDLCPQWPKAYFRQGVALQCLGRYGEALAAFASGLAQEPSNKQLMAGLVEASLKSPLRAALEPTLQQLRTMQLQESPFVVSSVVGQELLQATQYSAAVTVLEAALRIGSCSLKLRGSVFSALSSAHWALNQLDQAIGYMQQDLAVAKSLGDTAGECRAHGNLGSAYFSQGAHKEALTAHRYQLVLAMKCKDTQ-----------------------AAAAALTSLGHVYTASGDYPNALASHKQCVQLFKQLGDRLQEAREIGNVGAVYLALGECEAALDCHSQHLRLARKLHDQVEEARAYSNLGSAHHQRRQFTQAAACHEQVLRIAQALGDRSMEAAAYAGLGHAARCAGDASASKRFHERQLAMALAARDKLGEGRACSNLGIVYQMLGSHDAALKLHQAHLGIARSLGDRTGMGKAYGNMARMAHMAGSYEAAVKYHKQELAINQAMNDRSAEAATHGNLAVAYQALGAHDAALTHYRAHLATARSLKDTAGEACALLNLGNCLSGRQEYEEAVPHYESYLMLAQELGDVAAEGKACHLLGYAHFSLGNYRAAVRYYDQDLALAKDAQHRPNMGRAYCNLGLAHLALGHTAAALECQQLFLAVAHATNQLPAKFRALGNIGDILIRTGSHEEAIKLYQRQLALARAAGDRSMEAAACGALGLAHRLMRRWDKALGHHTQELTLRQELGDLSGECRAHGHLGAVHMALCSWTNAVKCYQEQLERAQEQRDAAVEAQAHGNLGIARLNMAHYEAAIGCLEAQLGTLERVSLPSTQADRARALGHLGDCYAALGDYEEALKCHDRQLQLALGLTSHRDQERAYRGLGQARRALGQLPAALVCLEKRLVVAHELHSPEIKALAYGDLGHVHAALGNHAQALNCLEHQRELAQGLQDRALESDAMCALGQVQQRMGQHAQALELHRQDLEICTELSAPALQARALSNLGSVHESLGQQAEALKCYERQLELSTDR---LAKAMACLALGRVHHQLEQHNQAVDYLRQGLASAQTTGKSEEEAKIRHQLGLALRSSGDAEGAHIQLETAAQLLESVRHE-QRSPETRQALYDLQTTCYQLLQVLLVALNRNEDALVAAERCKARGGADAVSGEGSKVPLADSES------IQETVDRGRTTVLYYSLAGDQLFTWLLEPHVGIVRFHAAKIDAHSLQLPLSLSEEEEEEEDLEMERELKLNRDQNQDQSEDQGTSNKANRLLERYMSLVRDNLGVN---SQSLLHEGDGSGWRASTEQLLEDLPGAGGSGGG--GFLRMVSRNQLLNSSNYSLSSLFSVGSVGGSVASLQGSTRSVGSRSSRRAPGLPVWRGPSCLHILYNLLLAPFDDLLPAGEADTNRQGRRELVLVLDSSLYLVPFAILRAAQEDGEYLCERCAILTAPSLQSMR--SRPRIRRD----RARPPKALVVGGPRIPSNLAELWGWAGAESPAALQEAAMVADMLQATALAGSNATKESVLAELPSAECVHFAANISWQLGAVVLSP---GDVVTAE---------------QQEQKE----PHEPQMTDFTLAAGELRQLRLSARLVVLSSYHSVEP-ITGDGVAQLAGGWLLAGAGVVLISLWPVPETAAKILLRAFYSALLQGARAARALAEAMQTVQHTKHFAHPANWAGFLLVGSNIRLSN-KVAMGHALCELLRTPERCRDALRVCLHLVEKSLQRIHRGQKNAMYTTQQSIENKAGPVAGWKDLLMAVGFRVEPAANGIPASVFFPQADPEERLAQCSASLQALLALTPATLQALGKLVHVNSAEYAGDIIAVVRNILAQFPGSNPATGSSSTKSDAIAETCFIEMPLSVRLWRVAGCHELLASVGFDLTEVGADQVILRTGKQANRRQCQFVLQALLALFDTREAPKNLGLDRDSDHSSSCESLAEPEMDVASIPPAASSTPSVNGGNKAPLPLHPRSAFISYVRRRGEPDGGRTDAIGGVGSGALDSSLANTTDSEHSLSDGYVTQPGFGLSNPRLGYASMRAPVRVSRPGGGGESDAAFTPSPPVTDPSLSLALAHQTRIRSLYSQTSSAAIVPPVATTLNRRPDSSSSASSTTDWEGSGHATVLRRGVSTAIPQQQPPLPPPRPPTFHNLSVGAGGRSKPKIKLGSAQSSLAARVNKEHALFMDRLSVRTELSAPGSGNAMTS--GSAARKPLALPEEEDVSNVVFNPSSLYFSQTDSDLLNEPKQEETPPPTKSSTKSLQDSMMRHMNRELTPSISEMYHDRNVGLGLAPPLSKLLLSPNYEEQEVVSITEACPQSGANLKTLVDAVSELELSGSSSGATMPTVVG----------GGANEVEGTSGTSAEATCPICGEPADVICRCKAVTIQKKSILKPWLSNVPDSSLVQASELTTADILERRLEIHTATSSELRSGAPYSVDLSRRDEGDGRSVADSQCSSNYKRVLASASGGALSLAGIGKGSEAEAQSASSGATCSSARLV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * . *..: : *. . * : .: ** :*: *. .:* *:******* **:.*** **: **.:** :** * ********* :* *: **:** :** * *:************* ***:.:***********:*.. **:.*:***::***:* :**** ***:.*:*::***** ******** * ::.*:*.******:**:****************:*:*.: ::: ******* ***:*** :************:**:* ::**** **:******* ** : **::**:******** ************** * ** * *.****:**:****:*:*: * *::**.***::*:.* .: ************:* **:* :* : *: **.:** * ::.:* *********** * . ::::**:**.:* :*: .****.*****::** *.:*:*****::** **:.*.* :. *:*****.. : * *: *****:*** *. :***:::*:**************** ** **: ** **.*:* .** ** **** ..* ** :*.*:**.** ** :* *: .***.** *****:.****: **:**:******** :.: . .:********. ** : : * ***: :*::*:: :: ********:***:: . . : ***:*::**.*:: . ** :**:* .*** *:*:::::*****:***** : ***.**.*********.**:*** .:* *.***:***: .:: ::.::***.:**:**:::** * *** :* **. *:::* .: **.** *:***** ********:* ::: *.:* .*. :** :******:.:** *.* ****:********** .. ** ***:** :*: ***: **:.***:* ::*:.::******** *.** * *:**:: **: *: **:*. * . *: *.** .*** .:**** .*: *::*.:::: **::: :***.** *:::.*** **::** *: *: *:****** ***:* :**: * *: ** *: *:*::*** * *.: : :*:****:.** ** :**:*.::::**..*** ::*. ** : . : :*. * * * *: * *******.. *::*** * .**::** :. :::: ..: : ... . :. **:::: **: ***: *:: . * :* :*:: .* . ****** :*:*:: * *::**** :*:. :..* *: *.. * *: **:**:**::. * ... ..* :*:*:***:..**::***:*:.: .: *** ** :::.*:::*: *: ::*: : .. * *:*.*::** : : * *. *:* :** **:::* . .*.** **** *:: *..***:***:::**:*.*:**:* *: . :: *:: .: .. * : :: *:*.:: :*:*..:****.* :. : :*.**: *: .:* *** **::***** :*:*::::****:**:* :*: :*.***:.** :* *:**:***** *:*.:::*.. . :*:** *:*: ***.****** ***********:.**:*****:***:***.* :.**: ** *****::*.:.*:**:**** :** :** ***::**:**.*. .:**** **: ...: * .*:*::. : : ..:.* : . * :.:**:***:.****:**::**** *** ::***:*****.** :*.**:**:***: * **.*.** .*. .* ..: : .: . .. *....:. . .:.::. *:: * : .:*:** :. . * * * : .*. . .: . * .: . . : .: *:* * . . : *: *: * :: .** ** *:*. . .. ..:*.: ..::: .*: . * * :: :: .:: . *:::. . . . : **.* .: : ** :*: :..: * :..:* :. : . ** .. . :* * :*. . . :*. * .. * : *. *. : * : .* : . . *. *.:.*. : *: . . :. . ::* * . . .. .*:.:*. * *:. : :: * :: : ...: ... : : : : : .. . *: . . *. . : .*:. ", "identical_positions": 1017, "similar_positions": 757, "identity": "39.04%" }, { "cls_id": "homologset.agr.MGI:2140882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80YF6-1", "uniprot_id": "UPK3B_MOUSE", "id": "Q80YF6-1", "name": "Uroplakin-3b", "aln": "MVRTRWQPPL-RALLLLVLVWLPQSLSL-------------------------------------------------------DLIAYVPQITAWDLEGKITATTFSLEQPRCVFDEHVSTKDTIWLVVAFSNASRDFQNPQ--------TAAKIPTFPQLLTDGHYMTLPLSLDQLPCEDLTGGSGGAPVLRVGNDFGCYQRPYCNAPLPSQGPYSVKFLVMDAAGPPKA-ETKWSNP-IYLHQGKNPNSIDTWPGRRSGCMIVITSILSALAGLLLLAFLAASTTRFSS--LWWPEEAPEQLRIGSFMGKRYMTHHIPPSEAATLPVGCEPGLDPLPSLSP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZKW6-1", "uniprot_id": "D3ZKW6_RAT", "id": "D3ZKW6-1", "name": "", "aln": "MEFTRMRPHP-WPLLLPVLMWLPQSLSL-------------------------------------------------------DLIPYTPQITARDLGGKVTATTFSLEQPRCVFDEHASSNDTIWLVVAFSNASRDFQNPQ--------TAAKIPTFPQLLTDGHYMTLPLSLDQLPCEDLTGGSGGVQVLRVGNDFGCYQRPYCNAPLPSQGPYSVKFLVMDAGGPPKA-ETKWSNP-IFLHQGKNPNAIDTWPGRRSGCMIVITSILPVLAGLLLLAFLAASTTRFSS--LWWPEEAPEQLRIGSFMGKRYMTHHIPPSEAATLPVGCEPGLDPLPSLSP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BT76-1", "uniprot_id": "UPK3B_HUMAN", "id": "Q9BT76-1", "name": "Uroplakin-3b", "aln": "MGLPWGQPHLGLQMLLLALNCLRPSLSLGEWGSWMDASSQTQGAGGPAGVIGPWAPAPLRLGEAAPGTPTPVSVAHLLSPVATELVPYTPQITAWDLEGKVTATTFSLEQPRCVFDGLASASDTVWLVVAFSNASRGFQNPE--------TLADIPASPQLLTDGHYMTLPLSPDQLPCGDPMAGSGGAPVLRVGHDHGCHQQPFCNAPLPGPGPYREDPRIHRHLAR----AAKWQHDRHYLHP--------LFSGRPPTLGLLGSLYHALLQPVVAGGGPGAAADRLLH--GQALHDPPHPTQRGRHTAGGLQAWPGPPPQPQPLAWPLCMGLGEMGRWE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CE76-1", "uniprot_id": "A2CE76_DANRE", "id": "A2CE76-1", "name": "", "aln": "-----MNTHNAIRLVSLLSIWMLAAQGQ----------------------------------------------------------IFQPQLAPANFLGRITSNTVILQQPYCVFTQTCPG-CEIWLVAALSTGTGNFNALVNISSPISLSVSPYPTAFLPSSAQFFLTRVGPLANFPCNTAP----AFPYFTVGADGICTG-INCNGVLPVGSIVSFRYLLIDPSNYTVVNMTNWGGP-FNLTTLLSYQTINDGLSARSGAMVVITTLLCVAVALLLLVFFIMLCVSCCGKKDGKTVTVMSSIRIPRYDTHNLKEHVHPYDNQAYEPDAKNYSRSQTLPKSPVRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :: : : . : **::. :: *::*:.*. *:** *** . :***.*:*..: .*: : : *: : .::* . ::** . : ** * * **. ** . : ::* * . . :: : :: : . * : . . . . ", "identical_positions": 32, "similar_positions": 59, "identity": "9.25%" }, { "cls_id": "homologset.agr.MGI:2140885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q769K2-1", "uniprot_id": "NAPEP_RAT", "id": "Q769K2-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDENENSQSPAPSHQYPKETLRKRQNSVQNSGGSESSRLSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNVSIPNVLR---WLIMEKDHSSVPGSKEELDKELPVLKP---------------------------YFISDPEEAGVREAGLRVTWLGHATLMVEMDELILLTDPMFSSRASPSQYMGPKRFRRPPCTISELPPIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWN-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDVQAKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLKSEDFFILKHGESRYLNTDDKAFEET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH82-1", "uniprot_id": "NAPEP_MOUSE", "id": "Q8BH82-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDEYEDSQSPAPSYQYPKETLRKRQNSVQNSGGSVSSRFSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNISIPNVLR---WLIMEKNHSGVPGSKEELDKELPVLKP---------------------------YFVSDPEDAGVREAGLRVTWLGHATLMVEMDELIFLTDPMFSSRASPSQYMGPKRFRRPPCTISELPTIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWS-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDLQTKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLSCEDFFILKHGESRYLNTDDRAFEET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ20-1", "uniprot_id": "NAPEP_HUMAN", "id": "Q6IQ20-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDENESNQSLMTSSQYPKEAVRKRQNSARNSGASDSSRFSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNPSIPNVLR---WLIMEKDHSSVPSSKEELDKELPVLKP---------------------------YFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWN-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNNDDENF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RJ40-1", "uniprot_id": "A0A2R8RJ40_DANRE", "id": "A0A2R8RJ40-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MAEQP------------------------LVGASSST-------PLDYRQEAD----------VTCSRRDSQGRFVNPWSTWHFPSYTTVAR---LFLTEKNNSKIPSAKEALDRELPIVQP---------------------------YFIQNPDQCGQTGTSVRATWLGHATVLVEMEGLLVLTDPIFSQRASPVAFMGPKRYRDPPCTIEQLPRLDAVVISHTHYDHLDAASVTALNSRFGSALHWFVPLGLAEWMQKTGCENVTELDWWVGSRIPG-HDNVSFFCTPAQHWCKRTPVDDNKTLWGSWSIVGSHS-RFFFAGDTGYCA-SFKEIGRHFGP-FDLAAIPIGAYVPRGIMKSQHVDPEEAVQIHIDVQAKASLAIHWGTFPLSYEHYLEPPARLREAMVNLGLNPDDFFTLHHGESRMINLKDMHSSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02883-1", "uniprot_id": "FMP30_YEAST", "id": "Q02883-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial", "aln": "MNFVTCHVQMRLLLQRRLVRLRESELFRPQTSLSTFKRHASQKTRPIQKCSRKYARILLLSVLVPYTGYAFYVSLATVKQIDLRNEMCQRLEENNNEVTYKGSLLKYSPLEVLGRFENPFEEYRIQTVFEFFANRVFELFERNRGGIPRDVHQMNKLMPVHKPTWGPNLVDVDPAEETALPLECKVLDELHIPTAVEENEGSKCPVYNTWLGQSCNYTVYNGLRILTDPLFSD-FLIHKTLGPKRITQMPSQITEVPKPDIILVSHNHPDHLDLESLEYWSGKD--SPLWIVPKGMKSYMTSNGCDNVLELSWWETLQVKKNNEIYHISATPAMHWSGRSLLDTNKSLWCSFLLTHHGNPILFHAGDTGYVKDLFVRIKERFGKGCKLALLPCGQYCPEWHQKPRHINPQEVLKIMKDLEARNVLGVHWGTFVLSGEYFLEPKEKL-EMLAEWGGFKDRCYCPELGKTECFD---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * * : :. * *** **: :: : . : *::.. :* . ::: :*: :* :: :: : ****:: . : * .****:**. :**** *. * ::* * :::**.* **** *: . : *:** *: .:* . **:** **.** : :: : **: **. *: :* ** ** *: : . :*.****** * .* .:** .** :* * * *. * :* :*::.::* *:::: :.:***** *: *::*** :* * : . * : : . *::. :: ", "identical_positions": 99, "similar_positions": 101, "identity": "20.58%" }, { "cls_id": "homologset.agr.MGI:2140902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z1-1", "uniprot_id": "LIN54_RAT", "id": "Q641Z1-1", "name": "Protein lin-54 homolog", "aln": "--------------------------------------MEVVPAEVNSLLPDDIMDTAITLVDEDS--------------------------IEAVIVSSPIPMETELEEIVSINSTGDSTATPISTEPITVYSNHTN-------------------QVAVNTTVSKADSNTTVKP---------AFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTAQAQPGDAKLPPQQIKVVTIGGRPEVKPAIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG-------PVITKLIFAKP-----INSKAVTGQTTQASPPVVTGRVLSQSAPGTPS----------------KTITISESGVIGSTLNSTTQTPNKIAISPLKSPN------------------------------------------------KTVKSAVQTITVGGMSTSQFKTIIPLAAAPNVQPIQVPGSK----FHYVRLVTATTAGSSAPPVSQSPSVNTQP-LQQAKPVVVNTTPVRMSVPFVQAQAVKQVVPKPINSTS--------QIVTTSQPQQRLIMPATPLPQIQPNLTN-----------LPPGTVLAPAPGTGNVG------YAVLPAQYVTQLQQSSYVSIAGN--------SNFTGTSGIQTQARVSFNGIIPSESASRP------------RKPCNCTKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMHC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571G4-1", "uniprot_id": "LIN54_MOUSE", "id": "Q571G4-1", "name": "Protein lin-54 homolog", "aln": "--------------------------------------MEVVPAEVNSLLPDDIMDTAITLVDEDS--------------------------IEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTN-------------------QVAVNTTVSKADSNTTVKP---------AFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTAQAQPGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG-------PVITKLIFAKP-----INSKAVTGQTTQASPPVVTGRVLSQSTPGTPS----------------KTITISESGVIGSTLNSTTQTPNKIAISPLKSPN------------------------------------------------KTVKSAVQTITVGGMSTSQFKTIIPLATAPNVQQIQVPGSK----FHYVRLVTATTASSSAQPVSQSPSVNTQP-LQQAKPVVVNTTPVRMSVPFVQAQAVKQVVPKPINSTS--------QIVTTSQPQQRLIMPATPLPQIQPNLTN-----------LPPGTVLAPAPGTGNVG------YAVLPAQYVTQLQQSSYVSIASN--------SNFTGTSGIQTQARLPFNGIIPSESTSRP------------RKPCNCTKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLSSQISDLLTRPTPALNSAGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMHC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MZP7-1", "uniprot_id": "LIN54_HUMAN", "id": "Q6MZP7-1", "name": "Protein lin-54 homolog", "aln": "--------------------------------------MEVVPAEVNSLLPEEIMDTGITLVDDDS--------------------------IEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTN-------------------QVAVNTTITKADSNTTVKP---------AFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG-------PVITKLIFAKP-----INSKAVTGQTTQVSPPVIAGRVLSQSTPGTPS----------------KTITISESGVIGSTLNSTTQTPNKIAISPLKSPN------------------------------------------------KAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSK----FHYVRLVTATSASSSTQPVSQNPSTNTQP-LQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTS--------QIVTTSQPQQRLIMPATPLPQIQPNLTN-----------LPPGTVLAPAPGTGNVG------YAVLPAQYVTQLQQSSYVSIASN--------STFTGTSGIQTQARLPFNGIIPSESASRP------------RKPCNCTKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMNC----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CM4-1", "uniprot_id": "LIN54_DANRE", "id": "Q08CM4-1", "name": "Protein lin-54 homolog", "aln": "--------------------------------------MDVVSPELNSLLPDEIMDTEAMDEDPPASHL--------------------TPPPQSAPESAQVPMETEVPEIISICPT-TASMQAISTNAKSTTSSTTQ-------------------LLLTPS----SSSSTTTKN---------ATPT-LPKIPSLS--VPPNHQLIINKVAAD-GKSPGGAVIKQEGQKLLVAGLSKTGQPIMLALPHAWN---KPATSQG-SGDAKSQPTQIKMVTAMGKP-------VIAVSSASQLVASSTP---LQAQHLKTLQITKKPPVSTAG-------PMITKLIITKA-----LNNKVLS--SPGSVSPVVTGRVVSQSTPLTPP----------------RTIAIGET---ISTVPQNAATNSKVAISPLKSPSKLTVVSVTSQSSNSPQKSMTLPLNVALGQQILTVQQSAVTSPAKAGSSQSTTQTVKPVQTVTVPTSQFKTIIPLTTPPNVQQIQVPGSR----FHYVRLVTATTGSSTVQTGG---STNTNPSIQPAKPVMMN-AAVRMSVPIVPAQTAKQVVPKPLSSAA--------QVVTTSQTPQRLIMPATHLPQIQPNLTN-----------LPPGTVLAPAHGSGNVG------YAVLPAPYVTQIPQPAFVTLTSS--------STFSTATPSQAQARLSLNGLSTSEANSRP------------RKPCNCTRSQCLKLYCDCFANGEFCNNCNCVNCFNNLDHESERLKAIKACLDRNPVAFKPKIGKGKEGESDRRHSKGCNCKKSGCLKNYCECYEAKIMCSSICKCMGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLSSQISDLLTRTTPAITSGGGKLPYTFVTKEVAEATCDCLLEQAEQAELTNQPQAMAERLILEEFGRCLHRIISFAGKAKTD-CPINC----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9E2-1", "uniprot_id": "LIN54_DROME", "id": "A1Z9E2-1", "name": "Protein lin-54 homolog", "aln": "MDTSGGNLDSLDDTEPLPELSFEDFLEPTSEKSSQHMEIEALDSEEDNIGGEDLADPANDSLNTPQFKKNVVHILEDKRLNSSGLTVLKSHAIKMVTAGGTPPAKAQVTDVKILNKLKPIPSSTLKIGSTTIATKSTPGSITKTLGNLTQIRTKDGQVIFVQKSVPGTQSSTAVTGSPSGGIRRLVAPSGIQKAVLSKGVTMASTGLVKAAVPAKASTSVPGSAITLKGIQPLAGGTAKASTSSTTATTSPSLAQPNKIQVVRTADGKIIKINQAGPSLLVNAKQGTGTTVTPGGSAATSVKLSPSTGNVVLNKPVGQVVVRTETPVKTATGSVASASATPGKMLVQSGGKQILVSNKNIIKLSPNASATSSTTHTTGGQTPSTSSGLHAIQLPGKGGIQYVRVLNNNKSAAGTSATASIPKTVQTQKITVVRPPAATGVPATSTTTSAAAASPAAASKANLAMGNTNKIVMRSMG--GSIVPLPSVQTLVSKRALGAISNASKPASAASSSATPSASQELPRKHRLTDLNVQLKQSASVSSEASDSSDAGPEAKKPRYVITMQQGSQKAASQPVQKLINRTANVQRVVSSSTSPSSNSTKKIYNYVQPTGSNGAKYMICNSGVPQSSTSAMRRGYTGYVENKTRRPPPISPQQHRFKQMGPQQQSKHQQLQAQAKQRIRQQQLPTEQSTPIKVEPKLPTLPPGVKANVPAKPLFEVLKPPATAAAAGAVDPLGGMTSRRKHCNCSKSQCLKLYCDCFANGEFCQDCTCKDCFNNLDYEVERERAIRSCLDRNPSAFKPKITAPNSGD-MRLHNKGCNCKRSGCLKNYCECYEAKIPCSSICKCVGCRNMEDRPD-VDMDSLDGLMGVEGQKKDKAKNKQLNEN-----------------RANIYFTDDVIEATIMCMISRIVMHEKQNVAVEDMEREVMEEMGESLTQIIAFAKEKQETSQIDESKPSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.: .* :.: ::: *. : : . .. * :::: :: : . .:. . : :. * : . . :.*.*:.. . *: : * . . . :: *. . . . .:. .* : : .*:. . * . . : ... * . . . :..:.: :.: : : : : : .:. . *: . *::. . :..* : :. .. : :. . .:* *.. :.: .:: *: . . * .. *: ::.* :. *. :..:. : . ::.. ::* .: :: :*: ...: . . ..:. : : : :. :. : : .::**... ..:: : .*.. : :: : :** ... . * .: . ::* : * * :: * : .. ..:. :. *: :: : .. : : . ** ***::* ***************::*.* :*:***::* ** :**::****** ****** :.*: * *.******:*************** *******:**:*:*: *: : * . *. *:: **.* .: . :.*.:* *** *:: : : . . ** ::**:*..* :* * : : .. ", "identical_positions": 136, "similar_positions": 268, "identity": "14.01%" }, { "cls_id": "homologset.agr.MGI:2140937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZN66-1", "uniprot_id": "GBP6_HUMAN", "id": "Q6ZN66-1", "name": "Guanylate-binding protein 6", "aln": "-------MESGPKMLAPVCLVENNNE-QLLVNQQAIQILEKISQPVVVVAIVGLYRTG----KSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVP-HPSKPNHTLVLLDTEGLGDVEKGD---PKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSP-RPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGN-NPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTG-----NRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQ--MAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKK-GDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR-EKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JDV3-1", "uniprot_id": "GBP6_MOUSE", "id": "A0A0G2JDV3-1", "name": "Guanylate-binding protein 6", "aln": "--------MTQP-QMAPICLVENHNE-QLSVNQEAIEILDKISQPVVVVAIVGLYRTG----KSYLMNCLAGQNHGFPLGSTVQSQTKGIWMWCMP-HPTKPEHTLVLLDTEGLGDVEKGD---PKNDLWIFALSVLLSSTFIYNSMITINHQALEQLQYVTELTELIRAKSSP-NPAGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDDYLENALKLIPGD-KPRMQASNSCRECIRLFFPNRKCFVFDRPTHDKELLQKLDSITEDQLDPKFQEVTKAFVSYIFTYAKIKTLKEGIKVTG-----NRLGILVTTYVNAINSGAVPCLDDAVTTLAQRENSVAVQKAADHYSEQ--MAQRLRLPTETLQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELIGENK-ELFLSKNEEASNKYCQEELDRLSKDFMENIST--FFVPCGHKLYMDKREKIEHDYWQVPRKGVKASEVFQSFLQSQAFIESSILQADTALTAG-EKAIAEERAQKVAAEKEQELLRQKQKEQQEYMEAQEKSHKENLEQLRRKLEQEREQDIKDHDMMLKKLMKDQKAFLEEGFKKKAEEMNKEIQQLRDVIKDKK--------RNTDRIKEALLNGFST--VLFHYLVR-----YLKHL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1MT80-1", "uniprot_id": "GBP4_DANRE", "id": "Q1MT80-1", "name": "Guanylate-binding protein 4", "aln": "-------------MDKPVCLIDTGSDGKLCVQQAALQVLQQIQQPVVVVAVVGLYRTG----KSFLMNRLAGKRTGFALSSNIKPKTEGIWMWCMP-HPTKAGTTLVLLDTEGLEDVEKGD---SKRDTYIFSLAVLLSSTLVYNSRGVIDNKAMEELQYVTELIEHIKVTP----DEDADDCTAFAKFFPHFIWCLRDFTLELKLDGKDLTEDEYLEFALKLRPGT-SKKVMMYNLPRECIRKFFPCRTCFTFPSPTTP-EKRSILESLSPAELDPEFLEVTKRFCKFVFDRSEVKQLKGGHTVTG-----RVLGNLTKMYVDTISSGAVFCLENAVIAMAQIENEAATQEGLEVYQRG--MEKLKSSFPLELEQVSSEHQRLSSMATQAFMARSFKDTDGKHLKALEGEMGKLF-DAYRSQNKQVGLETHCDLL--LYMRCKDPLILHVYFFPVNDARSKEKVEQNERSSLPISH--PRPDRPFQVKTPHVLEVPGASVYPEEGISFRTDVEPNFFKVRKLQVDDVQMNLVRQKDKMSVWTTTIWKEEFVHLQQVRDERKLNSEIEKNDFFNAHRVAFIERVTNVKS-IADKLHGQRIIHKELYSEITQTNVTRQQIMRKICDSVDSSGRIAKCKFIDILQEEERCLLEDLKQSES---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A7Z1-1", "uniprot_id": "A0AB13A7Z1_DANRE", "id": "A0AB13A7Z1-1", "name": "", "aln": "-------------MDKPVCLINTDSDGKLYVQPAALQVLQQIQQPVVVVAVVGLYRTG----KSYLMNHLAGKQTGFALGGTIESKTKGIWMWCVP-HPTKTGTTLVLLDTEGLGDVEKGD---SKHDTNIFCLAVLLSSTLVYNSRGTINNRAIEELQYVTELTECIKVKSS---DEDVDDSTEFVKFFPSFIWSVRDFTLERKIDGKDATEDEYLEFALKLKPGT-SKKITSFNLPRECIQKFFPTRTCFTFPFPTAP-EKMSTLESLSPADLSTEFLEVTKRFCKFVFDKSEVKRLKDGHTVTG-----RVLGNLTKMYVNTISSGAVPCLENAVIAMAQIENVAATQEGLEVYQRG--MEKVKCSFPLELEQVSSEHQRLSSKATQAFMARSFKDTDGKHLKVLEVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JTZ9-1", "uniprot_id": "A0A0G2JTZ9_RAT", "id": "A0A0G2JTZ9-1", "name": "", "aln": "MSSSNDPTVIPMAERRYGDLPETNTSDPETLTEEAVLSFHNISYRETVQSGFPLRQQTHVMERLSSISGIMGPGLNAIMGPQDGSRSLLLDVLAARRDPCGLSGDILVNGKPQPANFKCTSGYVPQNDVIMHTVTVRDNLEFSAALRLPMTITRNEKRRRINEVLELLHLEKEQNTKPRSKELRKRTSIAVELVTEHPILFLDDPTTGLDLRTTTDIIAVLRRMSKKGRTVIFSINQPQYSIFRFFDSLTLVASGKLMFHGPAQDALEYFTSAGYQYESHNNPADFFLDVINGGLCDTEEDGHEADEHEDLYERLHQVTEKLANMYAQSPLHSDTRAKLDQLLGEQKQDRRSAMETTFVTPFWHQFGWITLRSFKNFKGFPWVTVIQAIIAVILAVFVGTIFRLLQNVCTEVKARAGLLFFLTGFECILSVSAGELFLLDRNHFLHEHTSGYYRVSSYFFGKLLAELIPR------RLLPSMIFTLITYFIAGMKTGVKGFFVTIFTVMMLASSASSLSLSLGAGENTAALPTTLITIYFMFMLFFSGLSLFSINFLPQLSWIQYLSIPHYGFRALLHNEFLGQNFCPEHNTEEVSRCQNYVIRLQDTFWKTSRNQRLVIVLGCVCVCVCVCVCVCVCVSVCLCLSLCVSVYVSLCVKCPIREYVLQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. .. : *: :.:*. .* : . * : : :. : * . :. ..: : : . .* ::: .. :.: . .:.* :. ::* : : *: : :.*: * :: .: ..: :: : *: * : .*: : * : .* ** . .. :: .: . : : . * :: . . . * . . * :. .: ...: . * *: : . : : :::. . * .: * . . : . ", "identical_positions": 26, "similar_positions": 111, "identity": "3.9%" }, { "cls_id": "homologset.agr.MGI:2140940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1F2-1", "uniprot_id": "A0A0G2K1F2_RAT", "id": "A0A0G2K1F2-1", "name": "acetyl-CoA carboxylase", "aln": "MVLLLFLTCLVFSCLTISWLKIWG-KMTDSKPLSNSKVDASLLSSKEESFSASDQSEEHG----DCSCPLTTPDQEELASHGGPVDASQQRNSVPSSHQKPPRNPLSSNDTCSSPELQTNRVAAPGSEVPEANGLPFPARPQTQRTGSPTREDKKQAHIKRQLMTSFILGSLDDNSSDEDPSASSF--------------QTSSRKGSRASLGTLSQEAALNTADPESHTPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIETVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKISSTIVAQTLQIPTLPWSGSGLTVEWTEDSQHQGKCISVPEDVYEQGCVRDVDEGLQAAEKVGFPLMIKASEGGGGKGIRRAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKTVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPVSFETP-------LSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAE-KPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYVLKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGQHVEVGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAKLELDDPSKVHAAQPFTGELPAQQTLPILGERLHQVFHSVLENLTNVMNGYCLPEPFFSMKLKDWVEKLMMTLRHPSLPLLELQEIMTSVAGRIPVPVEKAVRRVMAQYASNITSVLCQFPSQQCWASGMLGKHSTTELQPELLKIATILDCHAATLQRKVDREAFFMNTQSIVQLIQRYRSGTRGYMKAVVLDLLRRYLNVEHHFQQA--HYDKCVINLREQFKPDMTRVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSEELTSILKELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAMPINVSD--PDLLRHSKELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVPTDTPLFSKACTSLYSEEDSKPS-----------------FFLSQSLQEEPIHILNVAIQCADHMEDERLVPVFRAFVQSKKHILVDYGLRRITFLIAQER-EFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRAMVMRYGSRLWKLRVLQAEVKINIRQTTSDCAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYP---------KDILTYTELVLDSQGQLVEMNRLPGCNEVGMVVFKMRFKTPEYPEGRDTIVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLSEEIKQIFQVAWVDPEDPYKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDSSLGVENLRGSGMIAGEASLAYEKNVTISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSYIPKDNQSPVPIITPSDPIDREIEFTPT-KAPYDPRWLLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRSVEVAVPADPANLDSEAKIIQQAGQVWFPDSAFKTAQVIRDFN-QEHLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDSLRLFKQPVLIYIPPGAELRGGAWVVLDSSINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLLGQLGTAQLPDK--DRKELESQLKAREDLLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTTRTYFYWRLRRLLLEAQVKQEILRASPELSHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSARDNLRSTIRENINYLKRDSVLKTIQSLVQEHPEATMDCVAYLSQHLTPAEQMQVVQLLSTTESPASH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4Z2-1", "uniprot_id": "ACACB_MOUSE", "id": "E9Q4Z2-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLFLTCLVFSCLTFSWLKIWG-KMTDSKPLTNSKVEANLLSS-EESLSASELSGEQ----------LQEHGDHSCLSYRGPRDASQQRNSLPSSCQRPPRNPLSSNDTWPSPELQTNWTAAPGPEVPDANGLSFPARPPSQRTVSPSREDRKQAHIKRQLMTSFILGSLDDNSSDEDPSAGSF--------------QNSSRKSSRASLGTLSQEAALNTSDPESHAPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRHQGKCISVPEDVYEQGCVKDVDEGLQAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKMVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPIPFETP-------LSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAE-KPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYALKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGDHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGVILEAGCVVARLELDDPSKVHAAQPFTGELPAQQTLPILGEKLHQVFHGVLENLTNVMSGYCLPEPFFSMKLKDWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRKYLNVEHHFQQA--HYDKCVINLREQFKPDMTQVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSDELTSILCELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHENKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAVPISVSN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVQTDTLLFSKACTSLYSEEDSK------------------------SLREEPIHILNVAIQCADHMEDEALVPVFRAFVQSKKHILVDYGLRRITFLVAQER-EFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRDMVMRYGSRLWKLRVLQAEVKINIRQTTSDSAIPIRLFITNESGYYLDISLYREVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYP---------KDILTYTELVLDSQGQLVEMNRLPGCNEVGMVAFKMRFKTPEYPEGRDAVVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLAEEIKQIFQVAWVDPEDPHKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDANLGVENLRGSGMIAGEASLAYEKTVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSFIPKDNRSPVPITTPSDPIDREIEFTPT-KAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFN-KERLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDGLRLYEQPILIYIPPCAELRGGSWVVLDSTINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLVGQLGKAQLPDK--DRKELEGQLKAREELLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTARTFFYWRLRRLLLEAQVKQEILRASPELNHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSAKDGLRSTIRENINYLKRDSVLKTIQSLVQEHPEVIMDCVAYLSQHLTPAERIQVAQLLSTTESPASS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00763-1", "uniprot_id": "ACACB_HUMAN", "id": "O00763-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLCLSCLIFSCLTFSWLKIWG-KMTDSKPITKSKSEANLIPS-QEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSVAGSS--------------RESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNG--VAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETP-------SNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAE-KPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQA--HYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDE---LCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPN----------------------RMTVPISITN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEARTSLYSEDDCK------------------------SLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIAQEK-EFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYP---------KDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTPQDYTRISSL---NSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPS-RAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFN-REKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDK--DRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKW2-1", "uniprot_id": "A0A8M9PKW2_DANRE", "id": "A0A8M9PKW2-1", "name": "acetyl-CoA carboxylase", "aln": "--------------------------MPSQTPISDCAG------------------------------------EHSPPMDPGLSSTSPRNEGIPPSATSDPTD-------------QSNITVS-----------HIESHRPRFGSGAQAKEKLK-----------FILGASEDNSSDDEPLVKNQ--------------TTTHQPKNTETLNAEPTASSEMPPTPVPSTG-LRPSMSGPHLLKKGKEHRKMEVHRDFTVASPAEFVTRFGGNRIIDKVLIANNGIAAVKCMRSIRRWSYEMFRNERTIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVEMIVDIAKRIPVQAVWAGWGHASENPKLPELLHKSG--ICFLGPSSKAMWALGDKVASSIVAQSAGIPTLPWSGTGLSVEWAEEEQRQGRLISVPPELYVQGCVKDVDEGLASAEKIGYPVVIKASEGGGGKGIRKVESSEDFPSLFRQVQAEVPGSPIFIMQLAEHARHLEVQILADQYGNAISLFGRDCSIQRRHQKIIEEAPASIASTITFEQMEQYAVRLAKMVGYVSAGTVEYLFSE-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGIPLYRIKDIRVLFGEAPWGDTTINFESP-------ECMPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVGATGGLHEFADSQFGHCFSWGENREEAISNMVVAMKELSIRGDFRTTVEYLIKLLETESFRNNDIDTGWLDHLIADKVQAE-RPDTMLGVVCGALQVADASFRESMSDFLHSLERGQVLPAASLVNTVNVDLIYDGVKYCLKVARQSPTTYVIIMNDSDIEVDVHRLSDGGLLLSYGGSSYTTYMKEEIDRYRVTVGNKTCVFEKERDPTVLRSPSAGKLLQYVVTDGSHVSASQPYAEIEVMKMVMTLHVQHSGCIRFLKRPGTVLEPGCIVALMDLDDPSCIHQVKPNTEPLPAQEPLPMVGERLHQVFHNVLENLVKIMDGYCLPEPYFSQKLKNWVDTLMKTLRDPSLPLLELQEIMTSVAGRIPVTVEKAIRKVMAQYASNITSVLCQFPSQ---------------------RIANILDSHAATLQRKADREIFFMNTQSIVQLVQRYRSGIRGYMKSVVLDLLKHYLQVEMQFQQA--HYDKCVINLREQYKPDMTPVLECIFSHAQVSKKNILVTMLIDQ---LCGRDPMLADELMVILDELTQLSKMENSKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETSIFDVLPSFFYHNNRVVCMAALEVYVRRAYIAYELNSLQHHQLQDGTCAVDFQFMLPSSHPNREPNATVSQHMPKSTGSSPTLNRLTLPVNDSGEFPAMRRQGSELFLEGALSPPCQRMGAMVAFHSFDHFKRCFDEVICRFVDPLCESSLFFDGCSTFCDGESCK------------------------NMKENPIHIINVSIKQADTEDDDALVTAFTAFAHSKKSLLYDYGIRRVTFLVAQKR-EFPKYFTFRARDEFHEDRIYRNLEPALAFQLELNRMRNFDLKAVPCAHHRMQLYLGAARVEEGAEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFSN-TPTRTDCNHIFLNFVPTVIMDPYKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGDVIPIRLFLTNESGYYLDISLYKEVNDPSSGQIMFQSYGDKQGPLNGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGPGDSYP---------KDVLMCNELVLDSQGNLVQMNRLPGDNEVGMVAFRMRMKTPEYPEGRDIIVICNDITHMIGSFGPQEDQLFMRASELARAEGIPRIYISANSGARIGLAEEIRHMFQVAWIDPEDPYKGFKYLYLTPQDYTRISSS---NSVHCHHVEEGGESRYILTDIIGKEEGIGVENLRGSGTIAGETSQAYKEIITISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVTHSTVPDDFEGVLTILQWLSYMPKSNQSPVPIKPATDPVDREIDFVPT-KAPYDPRWLLCGRPHPTVKGAWQSGFFDHGSFLEIMATWAQTVVVGRARLGGIPLGVIAVETRTVELAIPADPANLDSEAKLLQQAGQVWFPDSAYKTAQAIEDFN-REKLPLMVFANWRGFSGGMKDMYDQVLKFGSYIVDALREFSQPVLVYIPPNAELRGGSWVVIDPTINLQHMELYADRESRGGVLEAEGTVEIKFRKKDLLKTMRRIDPVYSRLAEQLGKPDLPSQ--ERKDLEAKLKSREEFLLPIYHQVAVQFVDLHDTPGRMQEKGVITDILDWKTARSFFYWRLRRLLLEEVVKKEIMQANQDLSNGHIQSMLRRWFVETEGAVKAYLWDNNKVVVEWLENNLSQQDGTRSVIRENIKCIKRDYALKHIRSLVQANPEVTMDCIIHMAQNITPSQRAKVCHLLATMDNSTTS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z784-1", "uniprot_id": "A1Z784_DROME", "id": "A1Z784-1", "name": "", "aln": "--MLITILGTLAAFLAFLLTLIFGRGQKRSKPVQSSAATSATTATTGDSDNGNTNHNSS---------VIAATATATTTSSKPPIAPAAPPSAVKASDKRFPKACIKKVQFSSESLRSDVDELCDQLKDSALSNLSNDNIRIACHQNNNNSSINKNQNNNSIDISISISKMSETNESNDTAAQSAEGERPSFLVGDEIDERAAEAGEACDEFPLKMQNDVRQNGDISERRKRLRPSMSRGTGLGQDRHQ-----DRDFHIATTEEFVKRFGGTRVINKVLIANNGIAAVKCMRSIRRWAYEMFKNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGSNNNNYANVELIVDIALRTQVQAVWAGWGHASENPKLPELLHKEG--LVFLGPPERAMWALGDKVASSIVAQTAEIPTLPWSGSDLKAQYS------GKKIKISSELFARGCVTNVEQGLAAVNKIGFPVMIKASEGGGGKGIRRVDTTEEFPGLFRQVQAEVPGSPIFVMKLARGARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAIVAQPEVFEDMEKAAVRLAKMVGYVSAGTVEYLYDP-EGRYFFLELNPRLQVEHPCTEMVADVNLPAAQLQIGMGIPLYRLKDIRLLYGESPWGSSVIDFENP-------PNKPRPSGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAASGGLHEFADSQFGHCFSWGENRQQARENLVIALKELSIRGDFRTTVEYLITLLETNRFLDNSIDTAWLDALIAERVQSE-KPDILLGVMCGSLHIADRQITESFSSFQTSLEKGQIQAANTLTNVVDVELINDGIRYKVQAAKSGANSYFLLMNSSFKEIEVHRLSDGGLLISLEGASYTTYMKEEVDRYRIVIGNQTCVFEKENDPSLLRSPSAGKLINMIVEDGAHVSKGQAYAEIEVMKMVMTLTSQEAGTVTFVRRPGAVLDAGSLLGHLELDDPSLVTKAQPFKGQFLQPENAPVP-EKLNRVHNTYKSILENTLAGYCLPEPFNAQRLRDIIEKFMQSLRDPSLPLLELQEVIASISGRIPISVEKKIRKLMTLYERNITSVLAQFPSQ---------------------QIASVIDSHAATLQKRADRDVFFLTTQSIVQLVQRYRNGIRGRMKAAVHELLRQYYDVESQFQYG--HYDKCVGLVREHNKDDMQTVVNTIFSHSQVAKKNLLVTLLIDH---LWANEPGLTDELANTLSELTSLNRAEHSRVALRSRQVLIAAHQPAYELRHNQMESIFLSAVDMYGHDFHPEN--------LQRLILSETSIFDILHDFFYHSNRAVCNAALEVYVRRAYTSYELTCLQHLELSGGLPLVHFQFLLPTAHPN----------------------RLFSRMSSPD--------GLDQAAAESLGNSFVRTGAIAAFDSFEHFEMYSDEILDLLEDFVSPAMVNAKVLEAVEAADSISDSRHSTSINVSLSDPVTRANAAEEAKSTEPIHIVSVAVRETGELDDLQMAQIFGNYCQEHNEELFQRRIRRITFAALKKR-QFPKFFTFRARDKFTEDRIYRHLEPASAFHLELNRMKTYDLEALPTANQKMHLYLGKAKVSKGQEVTDYRFFIRSIIRHSDLITKEASFEYLQNEGERVLLEAMDELEVAFSHPHAKRTDCNHIFLNFVPTVIMDPAKIEESVTKMIMRYGPRLWKLRVLQAELKMVIRQSPQSPTQAVRLCIANDSGYFLDISMYTEQTEPETGIIKFKAYGEKQGSLHGHPISTPYMTKDFLQQKRFQAQSNGTTYVYDVPDMFRQMTERHWREFSKARPTVDIRTPDKILIECKELVLEGD-NLVEMQRLPGENNCGMVAWRIVLATPEYPNGREIIVIANDLTYLIGSFGIKEDVLFAKASQLARQLKVPRIYISVNSGARIGLAEEVKAMFKIAWEDPEEPDKGFKYLYLSTEDYAQVANL---NSVRAILIEDEGEQRYKITDIIGKDDGLGVENLRYAGLIAGETSQAYEEIVTIAMVTCRTIGIGSYVVRLGQRVIQIDNSHIILTGYAALNKLLGRKVYASNNQLGGTQIMFNNGVTHKTEAIDLDGVYTILDWLSYIPAYIGCDLPIVLPNDRIERPVDFMPT-KSPYDPRWMLGGRVNPVNANDWENGFFDRDSWSEIMASWAKTVVTGRARLGGVPVGVIAVETRTVEVEMPADPANLDSEAKTLQQAGQVWYPDSSYKTAQAIKDFG-REELPLIVFANWRGFSGGMKDMYEQIVKFGAYIVDGLREYKKPVLIYLPPNAELRGGAWAVLDSLINPRYMETYADPEARGGVLEPEGIVEIKYKEKDLVKTIHRLDPTTIALKKELDEANASGDKVRAAQVDEKIKARIAVLMHVYHTVAVHFADLHDTPERMLEKECISEIVPWRDSRRWLYWRLRRLLLEDAYIKKILRAQDNLSVGQAKQMLRRWLVEEKGATEAYLWDKNEEMVSWYEEQIN----AESIVSRNVNSVRRDAIISTISKMLEDCPDVALDAVVGLCQGLTPVNRGVVVRTLAQMQLNEETSNSNQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00955-1", "uniprot_id": "ACAC_YEAST", "id": "Q00955-1", "name": "Acetyl-CoA carboxylase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MSEES------------------LFESSPQKMEY--------------------------------------EITNYSER-----HTELPGHFIGLNTVDK------------LEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDE---KTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLITHKMTAE-KPDPTLAVICGAATKAFLASEEARHKYIESLQKGQVLSKDLLQTMFPVDFIHEGKRYKFTVAKSGNDRYTLFINGSKCDIILRQLSDGGLLIAIGGKSHTIYWKEEVAATRLSVDSMTTLLEVENDPTQLRTPSPGKLVKFLVENGEHIIKGQPYAEIEVMKMQMPLVSQENGIVQLLKQPGSTIVAGDIMAIMTLDDPSKVKHALPFEGMLPDFGSPVIEGTKPAYKFKSLVSTLENILKGYDN-----QVIMNASLQQLIEVLRNPKLPYSEWKLHISALHSRLPAKLDEQMEELVARSLRRGA----VFPAR---------------------QLSKLIDMAVKNPE-YNPDKLLGAVVEPLADIAHKYSNGLEAHEHSIFVHFLEEYYEVEKLFNGPNVREENIILKLRDENPKDLDKVALTVLSHSKVSAKNNLILAILKHYQPLCKLSSKVSAIFSTPLQHIVELESKATAKVALQAREILIQGALPSVKERTEQIEHILKSSVVKVAYGSSNPKRSEPDLNILKDLIDSNYVVFDVLLQFLTHQDPVVTAAAAQVYIRRAYRAYTIGDIRVHEGVT-VPIVEWKFQLPSAAFS------------------------TFPTVKSKMGMNRAVSVSDLSYVANSQSSPLREGILMAVDHLDDVDEILSQSLEVIPRHQSSSNGPAPDRSGSSAS-------------------------------LSNVANVCVASTEGFESEEE-ILVRLREILDLNKQELINASIRRITFMFGFKDGSYPKYYTFNG-PNYNENETIRHIEPALAFQLELGRLSNFNIKPIFTDNRNIHVYEAVSKTSP----LDKRFFTRGIIRTGHIRDDISIQEYLTSEANRLMSDILDNLEVTDTS----NSDLNHIFINFIAVFDISPEDVEAAFGGFLERFGKRLLRLRVSSAEIRIIIKDPQTGAPVPLRALINNVSGYVIKTEMYTEVKN-AKGEWVFKSLG-KPGSMHLRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLT------DDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGR-ETESG--FEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREKLLDTMNRLDDKYRELRSQLSNKSLAPE--VHQQISKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEAS---RLEKIARIRSWYPASVDH---EDDRQVATWIEENYK-------TLDDKLKGLKLESFAQDLAKKIRSDHDNAIDGLSEVIKMLSTDDKEKLLKTLK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32874-1", "uniprot_id": "HFA1_YEAST", "id": "P32874-1", "name": "Acetyl-CoA carboxylase, mitochondrial", "aln": "--------------------------------------------------------------------------KGKTITHGQSWGARRIHSHFYIT----------------------IFTITCIRIGQYKLALYLDPYRFYNITGSQ------------------IVRLKGQRPEYRKRIFAHS---------------YRHSSRIGLNFPSRRRYSNYVDRGNIHKHTRLPPQFIGLNTVES------------AQPSILRDFVDLRGGHTVISKILIANNGIAAVKEMRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDN---KTNFVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKN--------LKRPSPKGHCISCRITSEDPNEGFKPSTGKIHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCEVNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDVIAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHE-----NSGIETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVS--------FPAK---------------------ELHKLMKRYLEEN---TNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENHDIHEERNLLNLRRKDLTNLKKILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSLKFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAENIHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKSIKIHKGAP-DLLMSWQFSSLRNYL-----------------------------VNSDGESDEFTKLSKPPSTS-GKSSANSFGLLVNMRALESLEKTLDEVYEQIH---------IPEERLSSG---------------------------------ENSLIVNILSPIRYRSEND-LIKTLKIKLHENERGLSKLKVNRITFAFIAANAPAVKFYSFDG-TTYDEISQIRNMDPSYEAPLELGKMSNYKIRSLPTYDSSIRIFEGISKFTP----LDKRFFVRKIINSFMYNDQKTTEENLKAEINAQVVYMLEHLGAVDIS----NSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVEICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIG-KNGNLILEPCS-EQSHYSQKSLSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKRYFPKHKLN------DSFFSWVELIE-QNGNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPREDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLYLAPKDMQLLKDSGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGATSKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTSNLQIGGTQIMYKNGIAHLTASNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDVDFKPAKQVPYEARWLIEGKWDSNNN--FQSGLFDKDSFFETLSGWAKGVIVGRARLGGIPVGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLPLIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVIDPTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKKLSLE--KQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRNELEWKKSRRFLYWRLRRRLNEGQVIKRLQKKTCDNKTKMKYDDLLKIVQSWYNDLDV---NDDRAVVEFIERNSK-------KIDKNIEEFEISLLIDELKKKFEDRRGNIV--LEELTRLVDSKRKR---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : : :** ** :*..:*********** :**:*:*:** * ::: ::**.*.**:**.**:***:***:*: ****.*******:::*:*:* : *:************* *** * . : *:**. .** :****::*::***: :* :****: : . :.: ::: :** . ::.* .: :*:*::*************:.: ::* *::*. * ****:*:*::. *******:******. ::*******:*******:****. :: *. **: *: *.: ************:. :. :.************* ***::.*****:****.**:*:: :.*** *:* * . : : *: * . ** :.*****:*::***** *.::******..********. * :*.*:****** *: *::*: : .::*:*:*::****:*:*.:***: ****. * .* * *.*** ** ..: :: : * *.::**: * .: *.:**: . * . . *::* . :* . .*:.. : : :* . :: ::*... **:: * .:* * *::: *: :.. * .:* * :*: : :*:.*** : * .* *: .. ***:*:*** *.* : * : :::** : .* ::. : **.** : : : . . * : : *: :. :. :: **. ** * . :::: .*:* ::: : .:: **:: .: .::. . . :.: .: .:* .* . .::..* ** *: : :. : :* . :: : :**::* ** *: ::.. * .. :: : : .:..*. .**:::*.:*: . *. : * :::: :: : . . : ** *: :: * *: * : .: : ::* * .* * : :: : : ::* . . * : . :: . .: : . : : :: : : . :: * . :.*:** *:::* . : * *:::*: ***.:: .:.: .: . :::: . :: * *** * **. . : * * * : : ::.* .. .:* ****:.* ... : :* . :: . ** : *: ..*: : :. .:* : * *** :. . * * .* :.. . : . : ** .*: ** **::*: ****:**.* :*:* * . .: **: : :* :::* ** * ***.:.: . * ***.**: :*: **:*. ***** ** :: :.:: ** :*:**::.****::*::**: :*::** *. :* ***:****:.:. : . *** **.*: : ::* : .:*** *: :* *** :* **.. .**: ****::***:*:******.**::.. ***** *:**:** .:*:** *:**.***. **::* * *: .: .*: *:*::* *: . * :* ::* *: .*: **:: *: .. :: *:**:.*: * :: **: *:.*******:*:***.***:::* :****** :* :::.****.*:*::****.:.**. *.**::::********* :**:::::*:*::***.* :.:*:::*:** .*****:*.*:*. ** :* *** ::*.****.:* * **::.:.::.:: *:* * * . . . :: :: * *: :* ::::*.*:** . :* * * . : * :* :::***** * * :.: : : . . : : . :.:. :. : *.: . : :: .. . . : .. : : : : : . : ", "identical_positions": 657, "similar_positions": 691, "identity": "25.36%" }, { "cls_id": "homologset.agr.MGI:2140945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TRW4-1", "uniprot_id": "PDS5B_RAT", "id": "Q6TRW4-1", "name": "Sister chromatid cohesion protein PDS5 homolog B", "aln": "MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKN--------LNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKT-----SISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAK-DSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDH--LLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQS---AAGKDAAKQICWVKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTD--------ASVKAIFS-KVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEALVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLER-----IAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTG---SKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKE--------------------TQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKL-----WVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKS------GTSTLRLLTTILHSDGDLTEQG-----KISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLR----LPLEYMAICALCAKDPVKERRAHARQCLVKNITVRREYLKQHAAVS------EKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDTKMN----EKLYTVCDVAMNIIMSKSTTYSLES---PKDPVLPARFFTQPDK-NFSNT--KNYLPPEMKSFFTPGKPKTANVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSTEMDHSENEDYTMSSPLPGKKSDKREDSDLVRSELEKPRSRKKASVTDPEEKLGMDDLSKLVQEQKPKGSQRGRKRGHAASESEEQQWPEEKRHKEELLGNEDEQNSPPKKGKRGRPPKPLGG-TSKEEPVVKTSKKGNKKKPAPPVVDEDEEEERQMGNTEQKSKS-----KQQRTSKRAQQRAESPETSAVESTQSTPQKGRGRPSKTPSPSQPKKNIRVGRSKQVATKENDSSEEMDVLQASSPVSDDTTQEGAEEEDISAGNVRRRSSKRERR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VA53-1", "uniprot_id": "PDS5B_MOUSE", "id": "Q4VA53-1", "name": "Sister chromatid cohesion protein PDS5 homolog B", "aln": "MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKN--------LNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKT-----SISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAK-DSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDH--LLNFVRERTLDKRWRVRKEAMMGLAQIYKKYSLQS---AAGKDAAKQISWVKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTD--------ASVKAIFS-KVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEALVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLER-----IAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTG---SKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKE--------------------TQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKL-----WVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKS------GTSTLRLLTTILHSDGDLTEQG-----KISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLR----LPLEYMAICALCAKDPVKERRAHARQCLVKNITVRREYLKQHAAVS------EKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDTKMN----EKLYTVCDVAMNIIMSKSTTYSLES---PKDPVLPARFFTQPDK-NFSNT--KNYLPPEMKSFFTPGKPKTANVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKREDPDLS--ELEKPRSRKKAPVTDPEEKLGMDDLTKLVQEQKPKGSQRGRKRGRTASDSDEQQWPEEKRHKEELLENEDEQNSPPKKGKRGRPPKPLGGGTSKEEPTMKTSKKGNKKKLVPPVVDDDEEEERQIGNTEHKSKS-----KQHRTSKRAQQRAESPETSAVESTQSTPQKGRGRPSKAPSPSQPPKKIRVGRSKQVATKENDSSEEMDVLQASSPVSDDTTQEGAEEEDISVGNVRRRSSKRERR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTI5-1", "uniprot_id": "PDS5B_HUMAN", "id": "Q9NTI5-1", "name": "Sister chromatid cohesion protein PDS5 homolog B", "aln": "MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKN--------LNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKT-----SISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAK-DSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDH--LLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQS---AAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTD--------ASVKAIFS-KVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLER-----IAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTG---SKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKE--------------------TQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKL-----WVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKS------GTSTLRLLTTILHSDGDLTEQG-----KISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLR----LPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREYLKQHAAVS------EKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMN----EKLYTVCDVAMNIIMSKSTTYSLES---PKDPVLPARFFTQPDK-NFSNT--KNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKS-----KQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPV-DDIPQEETEEEEVSTVNVRRRSAKRERR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IP12-1", "uniprot_id": "A0A0R4IP12_DANRE", "id": "A0A0R4IP12-1", "name": "", "aln": "MAHSKNRATDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSAQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFQVINNGHNQKVHMHMVDLMSSIVCEGDSVSQELLDTVLVNLVPAHKN--------LNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKT-----SVSDLSEHVFDLILELYNIDNHLLLSVLPQLEFKLKSNDNDERLQVVKLLAKMFGAK-DSELASQNKPLWQCYLGRFNDIHVPVRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTASKKDLSLVNDH--LLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQA---EAGKEAAKQISWIKDKLLHIYYQNSIDDRLLVERIFAQYLVPHNLETTERMKCLYYLYATLDGNAVKALNEMWKCQNMLRHHVKDLLDLVKQPKSD--------SYNKAVFS-KVMVITRNLPDPGKTQDFVKKLAQVLEEDEKIRKQLETLVSPSCSCKQAEVCVKEITKKLGSPKQPSNPFLEMVKFLLER-----IAPVHIDTESISALIKQVNKSIEGTADDEDEGVPTEQAIRAGLELLKVLSFTHPVSFHSAETFESLLGCLKMDDEKVAEAALQIFKNTG---NKLEDSFPHIKSVLLPVLQHKAKKGPPRQAKYAIHCIHAMFSNRD--------------------THFAQIFEPLHKGLDTDNMEQLITPLTTLGHLAMLAPEQFAAPLKSLVANFIVKDLLMNDRIPGKKTTKL-----WVPDDEVSPETSAKIQGLKLMVRWLLGVKNNQSKS------GNSTLRMLTAILSSDGDLTEQG-----KMGKPDMSRLRLAAGCAILRLAQEPCYHEIITLEQYQLCALVINDECYQVRQAFAQKLHKGLCRLR----LPLEYLAVFTLCAKDPVKERRAHARQCLVKNINLRREYLKQHAAVS------EKLISLLPEYVVPYAIHLLVHDPDYVKVQDIEQLKDIKEALWFVLEILMAKNENNSHAFIRKMVENIKQTKDGQCPDDAKIN----EKLYTVCDVAMNIVISKSTTYSLES---PKDPVLPARYFTQPDK-NFSNT--KNYLPPEMKSFFTPGKPKAANVLGAVNKPLSATG-KLQTKLSRMETISNASSNSNPSSPGRSKGRLDSG--DHSENEDISMKSPSETEKP---------------TRGRKRGAGASQDDKG---------QESKPKRGR--KKAANTSTDDAEDQWGEDSSLAEANLETEDEQNSPPKRGRRGRPPK---SAAAKEETPSKGRR--GRRKTAPPVEEDNEDEQQEEEDEDEEEDAGSENMEVKPKGRRGRKPKVDVSETASDSVETTPQKRRGRPPKSQTAAR---KASGGRSRAAAHQEEESEEEMDTVQQ--------SEEDEDESVDSSPKVRRKVGRRDRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8S6-1", "uniprot_id": "A1Z8S6_DROME", "id": "A1Z8S6-1", "name": "", "aln": "MAD---------IVYPTGCRPLVEDLGTDELIRRLKTLANVLQTMDQD-DNLYQQYIPLALHLLDDFFMQHPSRDVQLLIACCVADVLRVYAPEAPYKEQDQIKTIFKFFIKQLHGLKDPRDPSFKRYFYLLENLAFVKSFNMCFELEDCQEIFQDLFSTIFKIVNDQHSVKVTNFFLDVLSPLITEADNLSVELLDLILINIVEPYKS--------NNKFACQLTEQLLTKTGDALESTIKMFFNRALVMDKPN----TKLSITNKIYDIIYELNRINAGLLCSVLPQLENKLLSTDDAERLKATTLLSRMFSEK-DSQLAKKYPNLLKIFFGRFCDITEPVRIKCVQSSMHFLLNHPSLQHDITEKLRLRNHDLDEVVRHEVVMAIVETAKRDFTLVLEAPDLLEIVRERTLDKKYKIRRDAMNGLAYIYKRAICEPN--DLSTGLKVRVDWIKNKILHGYYKVGLEDRLLVERLLITCLVPYKLAPEERMKKLYHLLGDLDANATKAFVELQKNQMKTRNTVSDWIKLHHSKEFT--------PRVLSQLSAKQANIAKLLPDPLKAAEYLTQFSNNLRKDAQLLRCINIVLKRDVSCRECADTMGVLLKKLG-AHVQSNLYYNTVKMLIER-----VASVMVDKESIGVLISLIEQCIEKGSMCEEIGISAQEAGERGLKLLAMLSYVFSAHFFTDTSLRHLISLLSYEQDYVAPLVLKTLTHLGRYQPLIDDPTPAILDELAPVCKDFALIGTPKQAKHAVRCIFVNSQSSASTDGATSGAGSASTTTQTVHPIFNEIIETLRLKLTP-NCEHQRTKIVTLGHIAYNMPQAFLTPIKNMIARRIVKELLIQE-VPAQRDYELPEDSDWCAQEKLPPDTLCKLDALKAMARWLLGLR-TDEHA------AQKTFRMLAAFVNQRGDLLGQN-----RLCGAEKSWLRLGAACAMLKVCEQKGVGDQYSAEQYLQLSQLMADPVPEVREIFARKLHKGLSRSLPRNCLPLDFMGLYVLAGLETERKLQDLVRHYAETDVNKRREYLKTVAMTSPDSSTESQSLHILPDYMLAFAIPVLVHDPRFTNHEDYVQLRKMEKCLRFILEPLMAKRETFVHSFYKQLLQLIKHREFSLGSD-KRDN----YKMWALCDLAMYIIDSKFSPFDGNTSTFSMPLALPEMYYKEPAVANFQNN--DVYIP---LDVYTLG-----------------------AKSTSKAAATAMTTSRAAVAP----------------------------------------------------------------------------------------------------------------------------------------------------KRPAEQSIMDDENPQENNLFDN----------------------------IRAADTTEPMAKRTRAGAASAKS-----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04264-1", "uniprot_id": "PDS5_YEAST", "id": "Q04264-1", "name": "Sister chromatid cohesion protein PDS5", "aln": "MAKG---AVTKLKFNSPIISTSDQLISTNELLDRLKALHEELASLDQDNTDLTGLDK-YRDALVSRKLLKHKDVGIRAFTACCLSDILRLYAPDAPYTD-AQLTDIFKLVLSQFEQLGDQENGYHIQQTYLITKLLEYRSIVLLADLPSSNNLLIELFHIFYDPN-KSFPARLFNVIGGILGEVISEFDSVPLEVLRLIFNKFLTYNPNEIPEGLNVTSDCGYEVSLILCDTYSNRMSRHLTKYYSEIIHEATNDDNNSRLLTVVVKLHKLVLRLWETVPELINAVIGFIYHELSSENELFRKEATKLIGQILTSYSDLNFVSTHSDTFKAWISKIADISPDVRVEWTESIPQIIATREDISKELNQALAKTFIDSDPRVRRTSVMIFNKVPVTEIWKNITNKAIYTSLLHLAREKHKEVRELCINTMAKFYSNSLNEIERTYQNKEIWEIIDTIPSTLYNLYYINDLNINEQVDSVIFEYLLPFEPDNDKRVHRLLTVLSHFDKKAFTSFFAFNARQIKISFAISKYIDFSKFLNNQESMSSSQGPIVMNKYNQTLQWLASGLSDSTKAIDALETIKQFN--DERIFYLLNACVTNDIPFLTFKNCYNELVSKLQTPGLFKKYNISTGASIMPRDIAKVIQILLFRASPIIYNVSNISVLLNLSNNSDAKQLDLKRRILDDISKVNPTLFKDQIRTLKTIIKDLDDPDAEKNDNLSLEEALKTLYKAS---KTLKDQVDFDDTFFFTKLYDFAVESKPEITKYATKLIALSPKAEET----------------------LKKIKIRILPLDLQKDKYFTSHIIVLMEIFKKFPHVLNDDSTDIIS-YLIKEVLLSNQVVGDSKKEIDWVEDSLLSDTKYSAIGNKVFTLKLFTNKLRSIAPDVPRDELAESFTEKTMKLFFYLIASGGELISEFNKEFYPTPSNYQTKLRCVAGIQVLKLARISNLNNFIKPSDIIKLINLVEDESLPVRKTFLEQLKDYVANEL----ISIKFLPLVFFTAYEPDVELKTTTKIWINFTFGLKS--FKKGTIFERALPRLIHAIAHHPDIVGGLDSEGDAYLNALTTAIDYLLFYFDSIAAQENFSLLYYLSERVKNYQDKLVEDEIDEEEGPQKEEAPKKHRPYGQKMYIIGELSQMILLNLKEKKNWQHSAYPGKLNLPSDLFKPFATVQEAQLSFKTYIPESLTEKIQNN---------------------IKAKIGRILHTSQTQRQR--------------------------------------------------------------------------------------------------------------------------------------------------------LQKRLLAHENNESQKKKKKVHHARSQADD-----------------EEGDGDRESDSDDDSYSPSNKNETKKGHENIVMKKLRVRKEVDYKDDEDDDIEMT--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .. : :..:*:: *** : : : :*** : * . :::* . .:: : ***::*::*:***:***.. ::. ** :. *:. * * .. . : **: :: :* : :* ..:::: :*: ::. . . :: : .::. :: * *.:. *:* :: ::: . .. . ::: * .: :. :. ::.. : . : ::..:: .* . *: :*: : :* * :: * :...*:.::: * ::.. : ::.:: ** :*:: .: : : .: .: :::.: * * : :*: :: : .. :: : : . : :*: .:*. .: :* :*.. : .. : : ..: : ** .:: . *: :: ::*.: :*:: * : . :* :* .:: : * :.. :.: : : . . . :: *.*. *: : : : : * :: :: :. . : .** . .: . :: * : : . ..* :. :. :: : : .. .:. : : . . ::: .*: : : . :.: : . . : . *. :*:* : * . : :: * : : : : .: .: *. : ..::: ::*::*:.: : .. :: .: . *: :* :.. * .: : .*:::: :: . *:* : : ** *. ::::.. : . .: : * **: * .:*:. :.. :.:.:: : : . :. : : .: . : :* : . : : *: : .: .. * : . . :. * * : : : : *.. : : : : *:: : ::: *: . . : . ** :. : : . *:* . . :* : . :: ::.: ::.: . :: : . . .. ", "identical_positions": 108, "similar_positions": 439, "identity": "6.99%" }, { "cls_id": "homologset.agr.MGI:2140950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U315-1", "uniprot_id": "GLD2_RAT", "id": "Q5U315-1", "name": "Poly(A) RNA polymerase GLD2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPNSILGRPPFTPTHQQHNNFFALSPTLYSHQQLIDAQFNFQN-------------------VDLSRAVSLQPLTYGTVSPIQTSTS---PLFRGRKR-ISDEKAFRLDGKRQRFHSPHQEPTIINQLV------------PLSGDRRYSMPPLFHTHY----------------------------------------------------------------VPEIVRCVPPLREIPLLEPREITLPE------------------------------------------------------------------------------AKDKLSQQILELFETCQQQASDLKKKE-LCRAQLQREIQLLFPQSRLFLVGSSLNGFGARSSDGDLCLVVKEEPC--------FFQVNQKTEARHILTLVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNTVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHEINDASRGTLSSYSLVLMVLHYLQTLPEP-ILPSLQKIYPESFSTSVQLHLVHHAP-CNVPPYLSKNESSLGDLLLGFLKYYATEFDWNTQMISVREAKAIPRPDDMEWRN--------KYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWQRLKNKRDLNSVLP-----LRAATLKR-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YI6-1", "uniprot_id": "GLD2_MOUSE", "id": "Q91YI6-1", "name": "Poly(A) RNA polymerase GLD2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPNSILGRPPFTPTHQQHNNFFALSPTLYSHQQLIDAQFNFQN-------------------VDLSRAVSLQPLTYGTVSPIQTSTS---PLFRGRKR-ISDEKAFPLDGKRQRFHSPHQEPTIINQLV------------PLSGDRRYSMPPLFHTHY----------------------------------------------------------------IPDIVRCVPPLREIPLLEPREITLPE------------------------------------------------------------------------------AKDKLSQQILELFETCQQQASDLKKKE-LCRAQLQREIQLLFPQSRLFLVGSSLNGFGARSSDGDLCLVVKEEPC--------FFQVNQKTEARHILTLVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNTVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHDINDASRGTLSSYSLVLMVLHYLQTLPEP-ILPSLQKIYPESFSTSVQLHLVHHAP-CNVPPYLSKNESSLGDLLLGFLKYYATEFDWNTQMISVREAKAIPRPDDMEWRN--------KYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWQRLKNKRDLNSVLP-----LRAATLKR-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIY7-1", "uniprot_id": "GLD2_HUMAN", "id": "Q6PIY7-1", "name": "Poly(A) RNA polymerase GLD2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPNSILGRPPFTPNHQQHNNFFTLSPTVYSHQQLIDAQFNFQN-------------------ADLSRAVSLQQLTYGNVSPIQTSAS---PLFRGRKR-LSDEKNLPLDGKRQRFHSPHQEPTVVNQIV------------PLSGERRYSMPPLFHTHY----------------------------------------------------------------VPDIVRCVPPFREIAFLEPREITLPE------------------------------------------------------------------------------AKDKLSQQILELFETCQQQISDLKKKE-LCRTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSDGDLCLVVKEEPC--------FFQVNQKTEARHILTLVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHQINDASRGTLSSYSLVLMVLHYLQTLPEP-ILPSLQKIYPESFSPAIQLHLVHQAP-CNVPPYLSKNESNLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRPDGIEWRN--------KYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWHRLKNKRDLNSILP-----VRAAVLKR-------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503I9-1", "uniprot_id": "GLD2_DANRE", "id": "Q503I9-1", "name": "Poly(A) RNA polymerase GLD2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPRPYIFSHNDGPSSHLFQHVLPHN---VSQQQRIEAHLNSTNNFI-------------GPPMNAPRFIPTYQWTPVELSDVACSPNG--PMGNNRKRRIQDNSDINLKRQRFSCPSPHNQSARNSNFTS------QPVTRPVTG-REVTCPTCSSATF----------------------------------------------------------------IPG--GCVPSLGETCHQN--AFSPSS------------------------------------------------------------------------------VKDKLSQQILNLFFACEQQSDDLEKKE-SCRAALQTDIQKIFPCAKVFLGGSSLNGFGSRSSDADLCLVIEEGP------------VNHRKDAVYVLSLVRKLLY-KLS-YIEKPQLIRAKVPIVKFRDRISGVEFDLNFNNTVGIRNTFLLRTYAFVEKRVRPLVLVIKKWANHHCINDASRGTLSSYTLVLMVLHYLQTLPEP-VIPCLQRDYPTCFDPKMDIHLVPSGP-SDIPAFVSRNQSSLGDLFLGFLRYYATVFKWDKQVISVRMARTLPKSNCKEWKD--------KFICVEEPFNRTNTARAVHERMKFEAIKAAFIESHRLLQLRKDLNFILPKSKQMARPQTAPR-------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYS4-1", "uniprot_id": "GLD2B_DROME", "id": "Q9VYS4-1", "name": "Poly(A) RNA polymerase gld-2 homolog B", "aln": "MFSTRISGDMKIFAADVAESSVTATCNTSVQQQQSQQLEFRTRMSAGSPSSKSGQCHLKFGKYNNKTANLLRQVNSCHSSNSSSNTSNNNNEAIKGQQQQPLHYCNSNNSHSWARKKYFGNGNSNNSLLQQQQQPSSFFQRQQQQHQMQMQQEKQATNNNDALMKNQNVVNAHVSDCKSSDSNNNSTSSSNNNSTISSNNNNTSSASNNNTGSSSSCSNRTKPAKWLNENSSSSSSSNNNNISCRNNNTSSIDTKRRNSSAGATAAYYRKSESESGSSEGAAESTETEATRTGGCNSNRTAESSSADGGTQATMGKSQDQEQDQTVKQRPRQQPLSFWKTNYPQTSATQLKDKETVAAVVSAAAVAAAAAAASASEQQQQQQSLSIEHRRNSGYQQHQQHNYYPYYYSQPKQLTIASFLQKEMLPDSTEKSSSNTGGSNMIRSSSNGNSNFSRHQYGHQSTGSGYQQQQQRYRNAQNVYQQYQHQQQHHAQQHTHPHFRRKHSDNGSGINKKMHYSPPGKSGDPADRSASGQQQHHHPHQQQKTIEILASSHFNAMHRRMQGGNNKNGYYQHSYNPMTGEVGSTPTRSEHQNIYNLTYIHVDTEATGEAASAAGSTPVVKPSLLSKPNISITPASSTTPTTVDRALLPAVRSVSAPASGSALPAPANHVRNMFPPPPLAMLGGHGLLSPVTTTTPTKM-------------ISCAQLDEAITAAAASGDKLSTSPSYNQAGHYIMPPQQQQQQQLSSHPIPTGTSSHPPPPPPPHMFFHFADGFCNPGQGHQAPPATMWPHSSSPCYPASYGSSCGSGTGAGTSPHNNDGNAGALRPASPALSSSSLGSESQWSGTSNRSRLGHNGHPSISPTPSALGSAQLSPHLAEMRVQHPLHQQHPPSHASHRPHGQMGGHAMSSYVPHRPPPPPHPSISSPNPTPVATGAGGPWYEMILPPDRYLAQARNIEVTVQPEKLICMCKYDNLSAEIWKRFRGAQQTHNKFKLKMRLWRYLYLWMHQPMFERYRICLVGSTITGFGTDSSDIDMCLLPEQGVHPHQHQYHQHHHFHNEKRTEALIILTLFNAVLKDTEVFQDFNLIEARVPILRFKDISNGIEVDLNFNNCVGIKNTYLLQLYAQMDWRTRPLVVIVKLWAQYHDINDAKRMTISSYSLVLMVLHYLQHACVPHVLPCLHSLYPEKFQLGQQDCLDLDLI-EPIEPYQALNTQTLGEHLLGFFKYYS-TFDFRNFAISIRTGGVLPVSTCRMAKSPKNDVYQWKELNIEEPFDLSNTARSVYDGPTFERVKAVFLISARRLDHTLDLATIFRPIHHVPEHFPQLQQH-QQQFEQQLHHPISGQQRSAGGGGDGANPVPSTLNPDAASTFAETTAAHVA--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD44-1", "uniprot_id": "GLD2A_DROME", "id": "Q9VD44-1", "name": "Poly(A) RNA polymerase gld-2 homolog A", "aln": "------MSTAMAMAAAASSSAAAATATTTAISNSTNTTASPATTNTINTTTKTITTSEVPLEPASNMAPKALEIEDSGRNEPEDLEHGAAKPLEQRKTTVVHTCPRPPGGYKYSMEFLYGIGSGMAGIPLNIPTPSSITPRTVRSTAPLLTTHMPLLTNMGVAPSRPSGIRYPG---SAGGSNGTTVAASTTPSTTVTTSSGSPGSGAEAITSSVSSSGLPAAGLQAAQFICQGYMPTGPQRRLWHAENAVWQFDRNYPYNQAYSPPYGIPMMPVGFEHPYGQRIIYPGYYNQTPPGINPAAVAGLTRTNRPVTQQPHILTQPAVGTTESSEEAPATLGNAPQVSSTWRYGRPGTHRGRHAVPTAAAPALLHRDSKSFYNSIGSGMANGPRFKAPFVANVRNFQAGAVATVAAGGAATTAVVGTSAPATGAASSSDQNVATKRNHQGAATQNNHRNRHNAKKGGKNSVGKELTSNSSESLSNSSSKSQLNKRPSSSSSISPIKHPHRNYRNRMRYTATEPTEQKAATTTVPISNYQPPQQSTSTVRRTSKFQGSNAYQAHTAAGRQQSRFYQSR-HMDGYVFQSGHYMVYAAGAPPVGLRPGKSPVSEATGAPPGAAAATAAAATAVAATAAAAEGGGAAEGGGAAAAPVTASSATLEGEQPLDSDFDQRQEFADLGLDPANGGFSSDLEPNGIKQDTSELDTHSCLISHPNSEVDGDDNQSLASFAPSVESDDSDSELSDASVESVARDILVSCLAVATGAEEPDFSGPNLVPYGDMHYLKELD----KKNPPTNGYRSHRPYHQSHYAYHSQMSPRGLSCCGDMLNQHSEDLVFKLDQNQPDGIESGKNIFLREITEQPDNISVASNLSCSPSASSSKSVLAPMASKSNITMPEENNDDDELPLVVHNRYWREFFG----------------------------------YTPADRFLLRAKFVEMRRPPKVMGCKNKWDPLSLSVWKKFLESQQTRHVYKIKMRLWRAIYTVAMKN-YPRYGLYLVGSSISYFGSKCSDMDICMLACTNPN-------------IDSRMEAVYHLHVMKELLGRTNMFQDFNLIEARVPILRFTDRCHKVEVDINFNNSVGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNAKNMTISSYSLMLMVIHFLQVGASPPVLPCLHNLYPEKFGLLQPNDFGYVDMNEVMAPYQSDNSQTLGDLLLSFLHYYS-VFDYGKYAISIRVGGVLPIEVCRAATAPKNDIHQWNELCIEEPFDQTNTARSVYDTDTFERIKTIFVASYRRLDSTRNLSAIFEDYDGPTILMQQPSVDSEIELYEGQHHRLLPNRGSSRSNSAIPSPRPSILMVDKATTAIWDDINNKPDHPVLSHSNNYDATNECTGNGSLMGLKDNSVADKPPIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . . . . : . : * : : . * . : * : . : . * ** .: : * .:* : * * : : : * **::. **: .** *:*:: . : * : :: :**.*:***::* * :*.*:*.** ***:**.** *: :: *.**:.: :* **.:* **:*.. *:***:*:***:*:** * ::*.*: ** * : : .: : * ..**: :*.*::**: *.: . **:* . .:* : : :****: :****:*:: .*: :* *: * : *. :* :: ", "identical_positions": 95, "similar_positions": 113, "identity": "6.66%" }, { "cls_id": "homologset.agr.MGI:2140967", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PER3-1", "uniprot_id": "MARE3_MOUSE", "id": "Q6PER3-1", "name": "Microtubule-associated protein RP/EB family member 3", "aln": "-------MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPG-------------DQIF-NKSKKLIGTAV---PQR--TSPTGPKNMQTS---GRLSNVAPPCILRKNPPSARNGGHE---ADAQILELNQQLLDLK---LTVDGLEKERDFYFSKLRDIELICQEHE-----------------------SENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIT1-1", "uniprot_id": "MARE3_RAT", "id": "Q5XIT1-1", "name": "Microtubule-associated protein RP/EB family member 3", "aln": "-------MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPG-------------DQIF-NKSKKLIGTAV---PQR--TSPTGPKNMQTS---GRLSNVAPPCILRKNPPSARNGGHE---ADAQILELNQQLLDLK---LTVDGLEKERDFYFSKLRDIELICQEHE-----------------------SENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPY8-1", "uniprot_id": "MARE3_HUMAN", "id": "Q9UPY8-1", "name": "Microtubule-associated protein RP/EB family member 3", "aln": "-------MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPG-------------DQIF-NKSKKLIGTAV---PQR--TSPTGPKNMQTS---GRLSNVAPPCILRKNPPSARNGGHE---TDAQILELNQQLVDLK---LTVDGLEKERDFYFSKLRDIELICQEHE-----------------------SENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0D6-1", "uniprot_id": "A0A8M9Q0D6_DANRE", "id": "A0A8M9Q0D6-1", "name": "Microtubule-associated protein RP/EB family member 3", "aln": "-------MAVNVYSTSMTIENLSRHDMLAWVNDSLQLTYTKIEQLCSGVAYCQFMDMLFPGCILLKKVKFQAKLEHEYIHNFKVLQAAFKRMNVDKIIPVEKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDPQLARQGQDVTPPPNPG-------------EVFLFHKLKSPSRSSG---PQR--TSPTAPKTMPTP---QRAISSTPSTGIRRNTPISRNGG------DAEIMELNQQLMDLK---LTVDGLEKERDFYFSKLRDIELICQEHE-----------------------SDSNPVLGKIIDILYATEDGFAPPEDEEIDEQPQ-DQEEY----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B5B2-1", "uniprot_id": "A0A8M2B5B2_DANRE", "id": "A0A8M2B5B2-1", "name": "Microtubule-associated protein RP/EB family member 3", "aln": "-------MAVNVYSTSVTIENLSRHDMLAWVNDSLQLTYTKIEQLCSGAAYCQFMEMLFPGCILLKKVKFQAKLEHEFIHNFKVLQAAFKRMNVDKIIPVERLVKGKFQDNFEFVQWFKKFFDANYDGKEYDPIQARQGQDVAPPPNPG-------------EHFS-HKPKR-TGPSG---PQR--TSPTVPKNMPTP---QRVTTT-----IRKNPTHARNGGS-----DAEITELNQQLMELK---LTVDGLEKERDFYFSKLRDIELICQDHE-----------------------AESSPVISRIIDILYATEDGFAPPEDDEIDEQSHLDQDEY----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6P3-1", "uniprot_id": "A1Z6P3_DROME", "id": "A1Z6P3-1", "name": "", "aln": "-------MAVNVYSTNVTSENLSRHDMLAWVNDCLQSQFSKIEELCTGAAYCQFMDMLFPNSVPVKRVKFRTNLEHEYIQNFKILQAGFKKMSVDKIIPVDKLIKGRFQDNFEFLQWFKKFFDANYDGREYDPVAQRGGVKLGNGNGHGSNGG-SGVGSSNNDLHLMHRRPLQAPASGGRMPARVIASTAVSKVLPRT---NNAAPASRINACANSTGTVKKNDVSNSVNNQQIEEMSNQVMDMR---INLEGLEKERDFYFSKLRDIEILCQEADD----------------------AEAHPIIQKILDILYATEDGFAPPDDAPPE------DEEY----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQA0-1", "uniprot_id": "Q8IQA0_DROME", "id": "Q8IQA0-1", "name": "Microtubule-associated protein RP/EB family member 1", "aln": "MSEKSKTSVVNVRYTNKLSSNSSRAEMLSWVNNTLKSQFFKVEELCTGAAYCQLMDILFARSIPMQRVKFRTNVEYEYIQNFKLLQGCFNKFVVDKIIPIDRLVKGRYQDNFEFLQWFRKFFDANYESREYDPVIARNGAMLGLGSPPMEAKLRKSVNKSNPQTKPTEESSAQTDRATTEPKNQVYKSNSENKTIEEASAQTDLAITEPENQVHESQTKTTEKASAQTEKATTEPDSEGSIEELRNYCKYVSRMKQERNFYLSKLRAIDHICQKYNS----------------------GRDRVILEKITKIIYSE---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40013-1", "uniprot_id": "BIM1_YEAST", "id": "P40013-1", "name": "Protein BIM1", "aln": "---------------MSAGIGESRTELLTWLNGLLNLNYKKIEECGTGAAYCQIMDSIYG-DLPMNRVKFNATAEYEFQTNYKILQSCFSRHGIEKTVYVDKLIRCKFQDNLEFLQWLKKHWIRHKDESVYDPDARRKYRPIITNNSAT-------------------KPRTVSNPTTAKRSSSTGTGSAMSGGLATR---HSSLGINGSRKTSVTQGQLVAIQAELTKSQETIGSLNEEIEQYKG---TVSTLEIEREFYFNKLRDIEILVHTTQDLINEGVYKFNDETITGHGNGNGGALLRFVKKVESILYATAEGFEMNDGEDELNDKNLGEHGTVPNQGGYANSNGEVNGNEGSNHDVIMQNDEGEVGVSNNLIIDEETF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** ::*:*:*. *: : *:*: :*.****:*: :: : :.:***.:. *:*: *:*:**. *.: ::* : :::*:: ::***:**:**::*.: : : *:* * : . : . : : . . . .: : : :. :: **:**:.*** *: : : : . .: : *:*: ", "identical_positions": 47, "similar_positions": 79, "identity": "12.21%" }, { "cls_id": "homologset.agr.MGI:2140972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCA0-1", "uniprot_id": "DCNL4_MOUSE", "id": "Q8CCA0-1", "name": "DCN1-like protein 4", "aln": "MHSDAAAVNFQLNSHLSTLASIHKIYHTLNKLNLTEDVGQDDHQTGSLRSCSSSDCFSKVMPPRKKRRPASGDDLSAKKSRHDSMYRKYESTRIKTEEEAFSSKRCLEWFYEYAGTED--AVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGY-FTLQEWLKGMTSLQCDTTEKLRTTLDYLRSLLNDTTN-FKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWP------LFPVFHQFLEQSKYKVINKDQWCNVLEFSR---TISLDLSNYDEDGAWPVLLDEFVEWYKDKQMS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0F7-1", "uniprot_id": "D4A0F7_RAT", "id": "D4A0F7-1", "name": "", "aln": "MHSDAAAVNFQLNSHLSTLANIHKIYHTLNKLNLTEDVGQDDHQTGSLRSCSSSDCFSKVMPPRKKRRPASGDDLSAKKSRHDSMYRKYESTRIKTEEEAFSSKRCLEWFYEYAGTED--AVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGY-FTLQEWLKGMTSLQCDTTEKLRTTLDYLRSLLNDTTN-FKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWP------LFPVFHQFLEQSKYKVINKDQWCNVLEFSR---TISLDLSNYDEDGAWPVLLDEFVEWYKDKQMS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92564-1", "uniprot_id": "DCNL4_HUMAN", "id": "Q92564-1", "name": "DCN1-like protein 4", "aln": "MHSDAAAVNFQLNSHLSTLANIHKIYHTLNKLNLTEDIGQDDHQTGSLRSCSSSDCFNKVMPPRKKRRPASGDDLSAKKSRHDSMYRKYDSTRIKTEEEAFSSKRCLEWFYEYAGTDD--VVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGY-FTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDSTN-FKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWP------LFPVFHQFLEQSKYKVINKDQWCNVLEFSR---TINLDLSNYDEDGAWPVLLDEFVEWYKDKQMS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHX6-1", "uniprot_id": "DCNL4_DANRE", "id": "Q5RHX6-1", "name": "DCN1-like protein 4", "aln": "MHSDAS--NFQLNSHLSTLASIHKIYHTLHRLNLTEDVGPESHGT---------ACCSRAMPPRKKRRPTAGDDLSAKKSRQDNVYRKQEALQIQ-EAEAFSSKRCLEWFYEYAGCDD--VVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQSMGY-FTLQEWLKGMGSLQCDSTEKLRNSLDYLRSVLNDATS-FKLIYRYAFDFAREKDQRSLDLNTAKCMLGLLLGKTWP------LFPVFNQFLEQSKYKVINKDQWCNVLEFSR---TINLDLSNYDEDGAWPVLLDEFVEWYKDREMS--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWB1-1", "uniprot_id": "DCNL4_DROME", "id": "Q9VWB1-1", "name": "DCN1-like protein 4", "aln": "--------------------------MPRGKRRAADTISDN-------------------MDHGQPKR--------ARTS-YTSIPTQQSSRRHIRLEDGFSQKRCMAWFQEYTTPDEPETLGPDGMEKFCEDIGVEPENIVMLVLAYKMGATQMGF-FSQQEWLKGLTELDCDSAAKMVVKLDYLRSILNDPNS-FKSIYRYAYDFAKDSDQRCMDILTAKAMLQLLLGKHWP------LYPQFAQFLEQSKYKAINKDQWCNILEFSR---TISIDLSNYDIDGAWPVMLDEFVEWLRLQRSQVTSTTGSS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12395-1", "uniprot_id": "DCN1_YEAST", "id": "Q12395-1", "name": "Defective in cullin neddylation protein 1", "aln": "--------------------------MSNNKIKRKDASPEQEAIES--------FTSLTKCDPKVSRKYLQRNHWNINYALNDYYDKEIGTFTDEVSTVAHPPVYPKELTQVFEHYINNNLFDIDSLVKFIEELGYNLEDLATLCLAHLLGYKKLEEPLKREDFLSTWFMQGCSTISDMQECIKTLDVKLHEDLQYFTQIYNYAFNLILDPNRKDIDTDEGIQYWKLFFQPEYPVRMEPDLLEAWFRFLRDEGKTTISKDTWRMLLLFFKRYPTIQKIISDYDETAAWPFIIDEFYECLQDQQ----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : :: . : : : ... : : .. :.: ** *::* : *::. * ** :. .: :. :::*. *.: .: :. * *:: . *. **.**::: : ::: :* . *:: :* * : :**.:. ..*.** * :* * : **. :*:** .***.::*** * : :. ", "identical_positions": 41, "similar_positions": 80, "identity": "13.1%" }, { "cls_id": "homologset.agr.MGI:2140983", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TPD2-1", "uniprot_id": "F185A_MOUSE", "id": "Q7TPD2-1", "name": "Protein FAM185A", "aln": "--------MFGRLPPCASRVRAGALVG-----ALGARTCGSSGAQRQ-GSAPDDSGAGLARGALREWTLQVSPFGRLRARLPCHLAVRPLDPLAHPDGDRVQVAVCGVEHV-ARGLDSLQVKYDADRQEMAILSDDIDPQASVEVNAPVKFDLSIESSGSGSVKVQNIECDSCKIDTEQGTSILQSVKSQKLHVQTKGGDVICCGTVYGNIDIHASDKSTVSIEKLQGSCVNISTEDGLLQAKYLYTESSFLSSAAGNIALGNVHGNIILQSKMGNITVDSSCGCLKASSHQGAIDVYVSQLGEVALTTEEGSIAVKAPSSLRAYFKLSGKEVVVDEEAHVQEMAKDCKGDGVTVTGLMNQASKHERWINAIAPKGTVSFQHQSWFQSLKLPD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A565-1", "uniprot_id": "A0A8I6A565_RAT", "id": "A0A8I6A565-1", "name": "", "aln": "--------MFGRLPPCASRVRAGALFG-----ALGTRTCGSGGAERR-GSVPANPGAGLARGDLREWTLRVSPFGRLRARLPCHLSVRPLDPLAHPDGDRVLVAVSGVGSG-TRGLDSLQVKYDAALQEMAILSDDIDPEASVEVNAPVKFDLNIESSGAGSVSVQNIECDSCKIDTEQGTSILQSVKSQKLHVNTKGGDVVCLGTIYGNIDIHASDKSTVTIDKLQGSCVNISTEDGLLQAKYLYTDSSFVSSAAGDIALGNIHGNIVLESKMGNISVDSSCGCLKASSDQGAIDVYISQLGEVVLTSQEGSIAVKAPSSLRAHLKLSGKEVVVDTEAHVQEMAKDRKGDGMTVTGLMNQGSKCERWINAIAPKGTVRFQHQSWFQSLKLPN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N0U4-1", "uniprot_id": "F185A_HUMAN", "id": "Q8N0U4-1", "name": "Protein FAM185A", "aln": "MLAPCSGWELGCFRLCLRQVRLWAGAGRWACWACQARPYSSGGSERWPGSETEVPPPGPGRRTLKEWTLQVSPFGRLRARLPCHLAVRPLDPLTYPDGDRVLVAVCGVEGG-VRGLDGLQVKYDEDLEEMAIVSDTIHPQASVEVNAPLKFGLDIKSSGSGCVKVQSIEGDNCKIETEHGTSILQSVKGQKLHVQTKGGKVICLGTVYGNIDIHASDKSAVTIDKLQGSSVTVSTEDGLLKAKYLYTESSFLSSAAGDITLGSVHGNITLQSKMGNITVDSSSGCLKASTNQGAIDVYVSQLGKVELKSHKGSIIVKVPSSLQAHLQLSGKEVDVNSEVHVQEMAEVRKDDVVTVTGLMNQASKREKWIKADAPKGTVSFRRQSWFQSLKLQD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5R6-1", "uniprot_id": "A0ACD6B5R6_DANRE", "id": "A0ACD6B5R6-1", "name": "", "aln": "----------MFVCAVTRRLRHDTCAS------LFQRVLRLSQVSRSYTDAP--ATVKHLDKPIKHWEFLISPFTKVKCHLGCNISIKSLDPHTFPEADRAFITVHVTDPNQTVDVDRFQVHYDDQSSELEILADGIDSDVTVELTAPIKCDLQIKTKDKGNVKIQKMESDRCHVHTERGNCVLKSVKSHEVQVQSTGGNVTGLHTIHGNVDIGTSADGNVDIKKIQGTTMNLCMEHGDLKVKAIYAETTSVTTSSGNIQIGHVHGQALVQSETGNIVIDSSSGALKVFTVSGYIDVYVGQDGIAELHSQEGAVSVRVPTTIKTAVQLCGASVSISSDLACEETERVSADGKTTVTAYLNASTSEERWIKATAEKAVVNLKTQSWFETLRLGAQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::* : . * . .* . . . ::.* : :*** :::.:* *:::::.*** :.*:.**. ::* . . .:* :**:** .*: *::* *..:.:**:.**:* .*.*::.. * *.:*.:* * *::.**:*..:*:***.::::*::.**.* *::**:** :* .. * *.*:**: :.:. *.* *:.* :*:::: :::::*:* :* :**: ::*: *** :***.*.**. : .* ****:.* * . * :.:*:: *:.*::::: .:*.* .* :. : :* . .. ***. :* .:. *:**:* * *..* :: ****::*:* ", "identical_positions": 112, "similar_positions": 157, "identity": "28.35%" }, { "cls_id": "homologset.agr.MGI:2140991", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UN04-1", "uniprot_id": "UBP30_MOUSE", "id": "Q3UN04-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "---MLSSRAQAARTAADKALQRFLR--TGAAVRYKVMKNWGVIGGIAAALAAG----------------------IYVIWGP------ITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQ--------------------------------------------------CLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLR--MYRWQISSFEEQDAHELFHVITSSLE--------DERDRQPRVTHLFDVHSLEQQSEMAPR----------QVTCHTRGSPHPTTNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHP--LTLDHCLHHFISSESVRDVVCDNCTKIEARGTLTGEKVEHQRST----------------------------------------------FVKQLKLGKLPQCLCIHLQRLSWSSHGT------------------------------------------------------PLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKATENPGSAPEVQ---------------------------------------------DAQAAPKPGLSQPGAPKTQIFLNGACSPSLLPALPSPVAFPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSS-AYLLFYERVLSRVQQQGREYRSEE--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPG5-1", "uniprot_id": "UBP30_RAT", "id": "D3ZPG5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "---MLSSRAQAARTAADKALQRFLR--TGAAVRYKVMKNWGVIGGIAAALAAG----------------------IYVIWGP------ITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQ--------------------------------------------------CLSLTLLSLLKALSCQEVTEEEVLDASCLLDVLR--MYRWQISSFEEQDAHELFHVITSSLE--------DERDRQPRVTHLFDVHSLEQQSEMAPR----------QVTCHTRGSPHPTTNPWKSQHPFHGRLSSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHP--LTLDHCLHHFISSESVRDVVCDNCTKIEAKGTQNGEKVEHQRTT----------------------------------------------FVKQLKLGKLPQCLCIHLQRLSWSSQGT------------------------------------------------------PLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKATESPGSALGVQ---------------------------------------------DTQAAPKPGLSQPAAPKTQFFMNGACSPSLLPALPSPMAFPLPVAPDYSSSMYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSS-AYLLFYERVLSRVQQQGREYRSEE--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70CQ3-1", "uniprot_id": "UBP30_HUMAN", "id": "Q70CQ3-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "---MLSSRAEAAMTAADRAIQRFLR--TGAAVRYKVMKNWGVIGGIAAALAAG----------------------IYVIWGP------ITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQKEPPSHQ--------------------------------------------------YLSLTLLHLLKALSCQEVTDDEVLDASCLLDVLR--MYRWQISSFEEQDAHELFHVITSSLE--------DERDRQPRVTHLFDVHSLEQQSEITPK----------QITCRTRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHP--LTLDHCLHHFISSESVRDVVCDNCTKIEAKGTLNGEKVEHQRTT----------------------------------------------FVKQLKLGKLPQCLCIHLQRLSWSSHGT------------------------------------------------------PLKRHEHVQFNEFLMMDIYKYHLLGHKPSQHNPKLNKNPGPTLELQ---------------------------------------------DGPGAPTPVLNQPGAPKTQIFMNGACSPSLLPTLSAPMPFPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVSDDTVRKASLQEVLSSS-AYLLFYERVLSRMQHQSQECKSEE--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGT0-1", "uniprot_id": "UBP30_DANRE", "id": "A2BGT0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "-------MPWCKQGTTDKLVREFLR--TGAAARNKMMKNWGVIGGIAAAMAAG----------------------VYVLWGP------ISDRRKKRKGMVPGLLNLGNTCFMNSLLQGLAACPSFIRWLEDFTSQNSADRERTERET--------------------------------------------------QLSRSLMQLLKALSSHDPGEDDVLDAGGLLEALR--LYRWHISSFEEQDAHELFHVLTSSLE--------EEQERQPRVAHLFDMQTLEKSVESKEK----------NISCRSGGPLHPIPSLWRTRHPFHGRLTSYMACKRCEQQSPVHYDSFDSLSLSIPSIQWGRP--VTLDQCLQHFISSETIKEVECENCTKQQAGELVNGEVLESQRTT----------------------------------------------FVKQLKLG----------KRLTWSKEGS------------------------------------------------------PIKRQEHVQFTEYLSLDRYKHCSAAQ--SQQKTSRTNKAKASADPK---------------------------------------------DKAIAN--GVDSEHCNNNKPQSNGTFPSVFLHSPG--LSSQLNLTYDYSTSEYLFRLTAVLVHHGDMHSGHFITYRRCPAAPRGTSPFSSQWLWVSDDSVRKASLQEVLSSS-AYLLFYER----MQRPG--LRVEE--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W462-1", "uniprot_id": "UBP30_DROME", "id": "Q9W462-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30 homolog", "aln": "----------------------------------MESEKILMAAGVTVAAVVG----------------------AFVFWGP------SGSRLRQRRGQIAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNN------ASPDRKS--------------------------------------------------LITSMLNTLEVVNGTHATLRGDPYSPGAVLRALN--ALGWVIP-QEEHDAHELFHVLLTCLE--------EEAIRPQPLGCLSDALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAMLTDFLNMEYDESTSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVSPGTPFGFPLVSNPDSLATPMLGGERSSRPRLP----------------------------------------------QSQQQQDEGLNRRVSSSCRSLERLHRGPGRVSIWSNMMPSQVAHPFQGAMGAQIV-----CNGCGSKSAVRYDKFDSITLNLPPQRRTGLSLGHLLSEYITSEDLSDVKCDSCNETTTHTKSVTFAKLP----------------ACLCIHVARTVWLPTGQVCKRKDYVHFPESLSMAPYSFVQPHLNSQAGTPWGSTMSLYSSSLPMNNGVGGGEGFGTMFPKNLYRLLAVVVHSGEANSGHFVTYRR------GSLRNAHRWYYTSDTIVREVSIDEVLSVP-AYLLFYDR----GQQRQLNLR-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25037-1", "uniprot_id": "UBP1_YEAST", "id": "P25037-1", "name": "Ubiquitin carboxyl-terminal hydrolase 1", "aln": "MDLFIESKINSLLQFLFGSRQDFLRNFKTWSNNNNNLSIYLLIFGIVVFFYKKPDHLNYIVESVSEMTTNFRNNNSLSRWLPRSKFTHLDEEILKRGGFIAGLVNDGNTCFMNSVLQSLASSRELMEFLDNNVIRTYEEIEQNEHNEEGNGQESAQDEATHKKNTRKGGKVYGKHKKKLNRKSSSKEDEEKSQEPDITFSVALRDLLSALNAKYYRDKPYFKTNSLLKAMSKSPRKNILLGYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVAKSELPDDALVGQLNLGEVGTVYIPTEQIDPNSILHDKSIQNFTPFKLMTPLDGITAERIGCLQCGENGGIRYSVFSGLSLNLPNENIGST--LKLSQLLSDWSKPEIIEGVECNRCALTAAHSHLFGQLKEFEKKPEGSIPEKLINAVKDRVHQIEEVLAKPVIDDEDYKKLHTANMVRKCSKSKQILISRPPPLLSIHINRSVFDPRTYMIRKNNSKVLFKSRLNLAPWCCDINEINLDARLPMSKKEKAAQQDSSEDENIGGEYYTKLHERFEQEFEDSEEEKEYDDAEGNYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYIEETDALGNTIKKRIIEHSDVENENVKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVIPAPPINYARSFSTVP---ATPLTYSLRSVIVHYGTHNYGHYIAFRK----------YRGCWWRISDETVYVVDEAEVLSTPGVFMLFYEYDFDEETGKMKDDLEAIQSNNEEDDEKEQEQKGVQEPKESQEQGEGEEQEEGQEQMKFERTEDHRDISGKDVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *:.. * * .. :* * :.** * * ***:*::**.:::. :: :*: . :: * * . . : ... :* .: : ::.**:*:*: : : ** :: . . : . .. . : * . :. : . : .. : . * *. * . .. . . * *: . : . :* . . : : . : . . . : . . .: : . : * :*:** * : **::::*: * ** * .. **** . .::***: ", "identical_positions": 51, "similar_positions": 106, "identity": "6.19%" }, { "cls_id": "homologset.agr.MGI:2140998", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80U95-1", "uniprot_id": "UBE3C_MOUSE", "id": "Q80U95-1", "name": "Ubiquitin-protein ligase E3C", "aln": "MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAVIIQSFIRGYRDRKQQYFIQRSAFDQCTDSAQPGGTFCLADGPNLTLLVRQLLFFY--KQSEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCSDDSLNVALPMRMLEVFTSENTYLPVLQDSSYVVSVIEQILHYMVHSGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYSSCP----EASRHQVFSAFTEEFLGAPFTDQIFHFVIPAFADAQTVFPYEPFLNALLLLESQS-----SKRCSGVPWLFYFVLT---------------------VGENYLGALSED-GLLVYLRVLQTFLS---QLPAS------PTGTGCPDSTSDSEDDNEETDQ-PNSPE-----------DGRVSAP--YITEECLRKLDTKQQTNTLLNLVWRDSASEEVFTRMASICHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMTTQMITGSMVPLLQLISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQS---SMMPFTLEELILLSRCLRDACLGIIKLAYPETKPEVREEYVTAFQSIGVTTNSEMQQCIQMEQKRWVQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLEVGLES-LPLSVSEERQLAILTELPFVVPFEERVKIFQRLIYADKQEVQG-DGPFLDG------------INVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFN-PNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTS--ADVDIHHLASLDPEVYRNLLFLKSYEEDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTGANRIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPVSLEDLKSFTNYSGGYSADHPVIKIFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDEALLRSKLLYAIECAAGFELS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHB7-1", "uniprot_id": "D3ZHB7_RAT", "id": "D3ZHB7-1", "name": "Ubiquitin-protein ligase E3C", "aln": "MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAVIIQSFIRGYRDRKQQYFTQRSAFDQCADSAQPGGTFRIADGPALTLLVRQLLFFY--KQSEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQLKRLMSLCCRLLQNCSDDSLNVALPMRMLEVFSSENTYLPVLQDSSYVVSVIEQILHYMVHSGYYRSLYLLINSKLPSSIEYSDLSRVPMAKTLLENVLKPLHFTYSSCP----EGARHQVFSAFTEEFLGAPFTDQIYHFIIPALADTQTVFPYEPFLNALLLLESRS-----SKRSSGVPWLFYFVLT---------------------IGENYLGALSED-GLLVYLRVLQTFLS---QLPAS------PTGVGRPDPTSDSEDDNEETDQ-PTSPE-----------DGRVSAP--YITEECLRKLDTKQQTNTLLNLVWRDSASEEVFTRMASICHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMTTQMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQL---SMMPFTLEELILLSRCLRDACLGIIKLAYPETKPEVREEYVSAFQSIGVTTNSEMQHCIQMEQKRWVQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLEVGLES-PPLSVSEERQLAILTELPFVVPFEERVKIFQRLIYADKQEVQG-DGPFLDG------------INVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFN-PNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTS--ADVDIHHLASLDPEVYKNLLFLKSYEEDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTGANRIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPVSLEDLKSFTNYSGGYSADHPVIKIFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDEALLRSKLLYAIECAAGFELS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15386-1", "uniprot_id": "UBE3C_HUMAN", "id": "Q15386-1", "name": "Ubiquitin-protein ligase E3C", "aln": "MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAIIIQSFIRGYRDRKQQYSIQRSAFDRCATLSQSGGAFPIANGPNLTLLVRQLLFFY--KQNEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCNDDSLNVALPMRMLEVFSSENTYLPVLQDASYVVSVIEQILHYMIHNGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYNSCP----EGARQQVFTAFTEEFLAAPFTDQIFHFIIPALADAQTVFPYEPFLNALLLIESRC-----SRKSGGAPWLFYFVLT---------------------VGENYLGALSEE-GLLVYLRVLQTFLS---QLPVS------PASASCHDSASDSEEESEEADK-PSSPE-----------DGRLSVS--YITEECLKKLDTKQQTNTLLNLVWRDSASEEVFTTMASVCHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMSTRMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQS---SMMPFTLEELIMLSRCLRDACLGIIKLAYPETKPEVREEYITAFQSIGVTTSSEMQQCIQMEQKRWIQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLDVGLES-PPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQG-DGPFLDG------------INVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFN-PNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTS--ADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY19-1", "uniprot_id": "Q1LY19_DANRE", "id": "Q1LY19-1", "name": "Ubiquitin-protein ligase E3C", "aln": "MFSFEGDFRRTPKVSLGGASRKEEKASLLHRTQEERRKREDERKRLKNAIIIQSYIRGYQDRKQQYAIQRGSFDHCVCQCQSGSGPQLTDSAILSQLVRQLLFFY--RLSEDRPRMIWMCQCLVKHHAQFVKLLTGPERQICLFQIKRLLGHCCRLLQSCEDDSLNVAVPMRMLEVFSSERTYLPFLQDENCVTSLIEQILHYMVQKGFYRSLYVLVNHKLPSSLEYSDTPSIPLAQTLLEHTLKPLHFTYSSCP----PDTRQFVFSAFTEEFISAPFTEQIYHFFVPALSDPKLAFPFQNFLWSLQATIASS-----VQARTQAPWLFYFVLS---------------------VGESGLSSLSEE-GLLLYLNALQTLLP---LLPVT------ECNS-RADINSDSEDEEEMTVQHPAAPD-----------GSWISVH--YITEECVQKLDTKQQTNALLTLVWRDSASEDVFTMMASICHTLMVQHRMMVPRVRLLYSLAFNARFLRHLWYLITSMKTKMITGSMVPLLQVMSRGSPMTLEDSNRIIPLFYLFSSLFSHSLISVHDSEFFGSSAD--GQSQS---SMMPFSLGELVTLSRCLRDACLGIIKLAYPETKTEHKEEYVAAFRSVGVKTNSQVQQRIQAQQKRWVQLFKVITNLVKMLKARDIRRPFCPSGHWLSDEVNIRADKVTQLYVPSARHMWRTRRMGRIGPLQSTLDVGLEP-PPLSVSEERHLAILTELPFVVPFEERVKIFQKLIYADKREVQG-EGPFLDG------------VNVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFN-PNQGFFKTTNEGLLYPSPTAEMLVGESFTRHYYFLGRILGKALYENMLVELPFASFFLSKLLGTS--ADVDIHHLASLDPEMYRNLLFLKSYEGDVEDLGLNFTVVNNDLGEAQVVELKPGGKDIPVTTANRIAYIHLVADYRLNKQIRAHCLAFRQGLANVVNLEWLRMFDQQEIQVLVSGAHVPICLEDLKRFTNYSGGYSATHPVIKIFWDVVESFSDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGTDLERLPTASTCMNLLKLPEFCDPQLMRNKLLYAIESSAGFELS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W196-1", "uniprot_id": "Q9W196_DROME", "id": "Q9W196-1", "name": "Ubiquitin-protein ligase E3C", "aln": "MFGFDGEYRRRPVQSLGGASHTCDRDTVIRKAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDG----IVEDESLTFLLRRLNFFYSIREAKDSERLIEVCQQILRQPARLLQHS--SPDSLWLLRLCKLLDTCLLQLSLSHT---AQAIPLRMLETFTTVSSVQQYMKDEAVLFQYMERVFGFLIARNYFVRLRRLLDDKCPPLDGETLHAPSPLAEALLQLLLRPLEVAKRASAGGQMSSMSMAVCRNFTRDILATPHTDPLRYFVLPCFALN-VDFPFDLLMRSLYDALESAGPAESDSTSSRRSFLFYGVETGHKTTRMDSIFSSFLLNSLMVLDRRQLATLHQSPLLVIYVRLIAEMMPNILQLPKSTLRGHANAPHRHRDGDDDSEESEDEDEELPAARTLDYDMEQTCRTSGELSVKERECLLESIAILNETERVDFIVQQLDPHIENTHLIYALCEICHNLMIYNKHAVFEYKLLYTLAFTPKFIRAVWFKLAAESTQLG---FSAPLTLISKGVVPKHQGVDRTIPLLATFCMLFGRLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEIIQMSKTLKDISMGLVELAFPETR-----SNLANYRKVLGHTEADDKK-LRHQKQIWANLLNVVVFVLNQIHTRDLRLGFCPEDHWTVTRLDLPLDRPTDLPLTHS---SRLRGIRPFQPIRDFTREDFENGPPMSTKQIRSITILREIPFVVPFNKRVSILQSLVAASKMRVQGNMQAFLQGPS----------VLITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFD-PNRGFFMVTTDNKLYPNPNVADLFED-YEKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGKY--SDVDIHQLASLDPELYRNLLYLKDYSGDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPPFFIQNTG-DMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGFELS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53119-1", "uniprot_id": "HUL5_YEAST", "id": "P53119-1", "name": "E3 ubiquitin-protein ligase HUL5", "aln": "MLNFTGQTRRR-NVNLGNRTRNSKKD-LLEKAKRERERRAQDKLKEDASKTIQKSIRRHFSNVRLFKNTFTSSQLVHMIPAYGG---------------KLIYYIS----------QYDLQQLLKLSHNFLSSYPNSLGNRQLLSLLKLYQDDALVAETLSDLNMDCPTVDEFLDSLSVYLCRASFLSYS---------------------------------------------SASKLADVIEAWEVMHSSAS--------ISIFSISIGSYEKRPFALQFYCILAERNLLPQLINTNPILWDNMAKTYSHCSK----------------------------------------GGQKNIAKLLIP------------------------------------NFNNHIAPS-------VLRSD-----------------------NDYVLKFYEKAFIDEVIATTANYVSDEDHVKNLMCYIASSPNQSCKNSVLITLLSNKDFVRRLSWEFFHTKFNAS-------------------------KTEAHPLFSVLAQLIDMHLLISTDRELLD--------------YNSVIPIEELKKFTSTLKDFTFRQYWELPKSERNPMLKEAVPLLSKVYERDSRLHFLSTENNPTYWENSEKQFLNLRFYEELQEYEDLYR---EHLEEESDEDMEKEIDLDKERP-------------PLKSLLLNKMKK-RLKSSLRFRKLEILLELPFFIPFEERVDLFYMFIALDKKRLSLDDDHNLINMFTPWASTGMRKQSAIISRDNVLEDAFNAFNSIGER-FKASLDVTFINEFG-EEAGIDGGGITKEFLTTVSDEGFKDPKHELFRTNDRYELYPS----VVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLNYSNGFLSSFSDLGSYDSVLYNNLIKLLNMTTDEIKSLDLTFEIDEPESSAKVVDLIPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLISGERDNIDLDDLKSNTEYGG-YKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALDPKFGIRNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAINSGARFDLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.* *: : .**. ::. .: ::.:: **.:* : : : . : :*. * . . : : * :* :: * ::: ::. . *: : :* . . .:*: :: :. : * :.. .. :.. : . *.: : :. . : : . .. :. * : .. . : : : . : :: . . . : . ** . * :: .:. . . **: :. *:. * * *:. :.: *: :: *:* : . : . :. .: . . : * : : . : . :: . : . . : :: :* . *::. :: * . * : :* *:**.:**::**.:: :: .* .:. * . : *. : ***:: : . .* :: : : ::. * :********: :***. : . .*. *:: :* .. ***. : :: :*:*:::**.:**::*:::.:* ***.** . .: .*.* *. :*.**: * . * . .. ..:::*:* *.. ** * : *: ::**:** : **: **: :: .*: **.. *:*:*:** . : *:*** :*.* :. . * ** *:: * :: ::****** .:.** *** * * * *:* * : ******** ****** : :*.******:..* *:**", "identical_positions": 166, "similar_positions": 274, "identity": "14.32%" }, { "cls_id": "homologset.agr.MGI:2141032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6J4-1", "uniprot_id": "ALKB2_MOUSE", "id": "Q6P6J4-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "------------------------------------------------MDKFLVRPDLRDLQGGGEEPAPTGGASGDLKSPDWRHLRAEGLSCDYTVLFGKAEADKIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLTPKPWVPVLERVRDRVCEVTGQTFNFVLVNRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFIFRHKDSRGKRPRRTVEVVRLQLAHGSLLMMNPPTNTHWYHSLPIRKRVLAPRVNLTFRKILPTKK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5G5-1", "uniprot_id": "A0A0G2K5G5_RAT", "id": "A0A0G2K5G5-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "MCRALARVAAPDPPVEHGCVPVLAYPAGRRTEAPCFSGTRLWLAGGGGMDRFLVRPDRGDIQGAAEEPAPTGEASGDMQSPGWQHFRAEGLNCDYTVLFRKAEADQIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLTPKPWIPVLERVRDQVCRVTGQTFNFVLVNRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDILFRHKDSRGKRPRRAVEVVRLQLAHGSLLMMNHPTNTHWYHSLPIRKRVLAPRINLTFRKILPTKK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NS38-1", "uniprot_id": "ALKB2_HUMAN", "id": "Q6NS38-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "MDRFLVKGAQGGLLRKQ------------EEQEP------------TGEEPAVLGGDKESTRKRPRREAP--GNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTKK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3QK41-1", "uniprot_id": "A3QK41_DANRE", "id": "A3QK41-1", "name": "DNA oxidative demethylase ALKBH2", "aln": "MDKFLTRKRKR-----------------------------------SSEEPDEWKTEALIKKPTEEEECEEGEEEFSNPIP-WQKIEAEGLDCDYSLLFNKEEADHLFNQLEEEVEYFTGDNAKLQVYGKSYNIPRKQATYGDEGLMYSFSGVNLLAKPWTSTLEHIRDAVTKATGYTFNFVLINRYKDGHDHIGEHRDDERELDPACPIASVSLGAARHLIFRHRDARTGPRKRQIEPVKLELANGSLLLMNFPTNTYWYHSLPIRKKVITPRINLTFRRIVKNRQKNGTKTE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .. . * *:::.****.*.*::** * ***.:*.:**:******* *::**:** :.:********* ** *:***:.* .*** ..**::** * .** ******:****** ************* *..******:**.*.::***:*:* * : *:* **:****:** ****:******:**:*::**:*****:*: .:: ", "identical_positions": 127, "similar_positions": 59, "identity": "43.2%" }, { "cls_id": "homologset.agr.MGI:2141041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DUQ1-1", "uniprot_id": "PRA15_HUMAN", "id": "P0DUQ1-1", "name": "PRAME family member 15", "aln": "MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS----HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60810-1", "uniprot_id": "PRAM4_HUMAN", "id": "O60810-1", "name": "PRAME family member 4", "aln": "MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMKGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS----HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VT98-1", "uniprot_id": "PRA20_HUMAN", "id": "Q5VT98-1", "name": "PRAME family member 20", "aln": "--MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWPFLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPLQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS----DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3YUJ6-1", "uniprot_id": "D3YUJ6_MOUSE", "id": "D3YUJ6-1", "name": "", "aln": "--MSGQTPPTLQKRARQTQLRDEALAISPLENVPAVYIPWLFQEAFAGRHNSLIKTMVAAWPFQYLPVGSLINMHNLETLQALLDGVDRRLTRKFPPGRPKLQVLDMRNVHHVFWNIGSDANDSDSDAETLDEKQVVKALPRYALRQRLKIIVDLSISS-QLNEEKAYFLNWAKQRKGSINFCCTKMKIWDAPDKVIREIMNVFHPEHITELELYTDWTLLRLAHFAPYFGQMKNLEKVFLAPLHKNTSPIMNITGASKVKCIKKIISQFSKFNCLQHVFMKRVHFLRDHLHQILGCLRTPLQTLSITHCLISQTDLDSFSCCHNLFKLKNLEIRGVTLFALDLMPLRGLLGKLAGTLKSLDFQWCSMKDSQLIVLLPALSQCSQLNQINFYSNDFSMAILKDLLQHTATWSKMNVEQYPVPLECYDALGHVSRERFVELCQELMDTLRAKREPKSISFATNVCQNCGKTCVYGQGARLCSCLQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *** * : * :: ***:***:*.**::*: :* ** ***: *: . :* ** :*** **: .*:: *::**:***:* *. . * ******:::* . ** : *:* . :: ::: :: ** :* *.::::* :.. *:* : :: *.***:. :::**.*:*: . : **.*:: .: : * *:*: .*.* *:.*:**:*:*:**.*:.*: . . :: .* : :.:: :** *:.***:::*: * **..**.*:*.**:*.*: *:**:*:: ::**. :* .: :**.*:: * * .*:**: ** *:*.**: **:: *.: ***: .:*****:* :*. :.* .* :. * *::** ** .:: :* **.* *.*.. * :. .**.:: ***. :* *.*: * *.*: * :**: ..*. . .* ", "identical_positions": 170, "similar_positions": 172, "identity": "35.12%" }, { "cls_id": "homologset.agr.MGI:2141043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3ZAV0-1", "uniprot_id": "CCD60_RAT", "id": "Q3ZAV0-1", "name": "Coiled-coil domain-containing protein 60", "aln": "MTKAPATKKLQRVPS-KAIWLFSGSDQLT-QASDKTVKSTKSMDKEIVNLKKDLIRSRFLIQCVKIGRGYFTMLQEETAFKKHQQHLKKLQEEELNKFQPAKKYSDIQCRDTLLTTYEYEKMKKLEAGIIIRPFTPIHNCIMAPSLPESHVDPLFRQLCALHWLLEALTIDHTHHTMRPVIACWNPKDPGGSKSTIKKINKDKSMGQRWDHFVTAPKTKKFKAPAIR-SLATRKPSRRGSALSLTRTSGGSSPQSSMMSVNPSSDEP-------TGSKDIEDNESSSTKPEEEVLHFSLQKLLEMVREDARRTILMETEMQKKAPSILSLVKQVKSDYGWKDWQTTHKSSERSSTTSGESHIQVTQKKSKGRANRDI-IYCKTGICNTMRAKFYSVAQEAGFCLQDKMEILKKRQEERGLQKFHSFIVTSNFQKDIAKMRHQVSMVKGDAEEMADHWYFDLLSKLPEDLKSFRPAKKILTKLQKFGENLDLRIRPHVLLKVLQDLRIWELCSPDIAVAIEFVREHIIHMPQEDYVNWLQSRVNMPIRHRPILT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4J0-1", "uniprot_id": "CCD60_MOUSE", "id": "Q8C4J0-1", "name": "Coiled-coil domain-containing protein 60", "aln": "MTKVPATKKLQKITSKKALWLFSSADQLTQQASDKTAKNSKYIDKEIANLKKDLMRSRFLIQCVKIGRGYFNILREENAMKKKQQLLQKLKEEELNKFQPAKKFSDIHCRDNLLATYDCEKLKKLEAGIIIRPFTPIHSCLMAPSLPESHVDPLFRQLCALHWLLEALTIDHTHHTMRPLIACWNPKDPGGSKSTIKKINKDKSMGQRWDHFVTAPKTKKYKAPAIRTAMASRKPSRRGSTLSLTRTSGGSSPQSSMMSVNPGSDEP-------MGSKDIEDNESSSTKPEEEILHLYLQKLLEMVREDARRTILVESEIQKKAPSILSLVKQIKSEYGWKEWQTTHKSSERSSTTSAESHIQVIQKKSKSRVNRDI-IYCKTGVCSNMRAKFFSVAQEAGFCLQDKMEILRKRQEERGLQKFHSFIVTSNFQKDITKMRHQVSIVKGDAEEIADHWYFDLLSKLPEDLKSFRPAKKILMKLQKFGENLDLRIRPHVLLKVLQDLRIWELCSPDIAVAIEFVREHIIHMPQEDYINWLQSRVNIPFRQRTILT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWA6-1", "uniprot_id": "CCD60_HUMAN", "id": "Q8IWA6-1", "name": "Coiled-coil domain-containing protein 60", "aln": "MTKVPATKKLQSSPNSGAVRPFYASENLR-QVPDKPMKSIKYMDKEIINLKKDLIRSRFLIQSVKIGRGYFAILREETAKKKKQQQLQKLKEEERNKFQPAEKISEIHYGDTLLSTYDDEKLKTLGARVTRRPFTPIHSCIISPSLTEAHVEPLFRQLCALHWLLEALTIDHTHHTMKPVITCWNPKDPGGSKSTIKKINKDKSMGQKWEHFITAPKTKKFKIPTMR--VTNRKPSRRGSTLSLSRASGGSSPQSSMISVNPGSDEPPSVNTQVTSSKDIEDNESSSTKPDEEPLYMNLQKLLEMVREDARRTVTIENGMQRKAPSILSVLKQNKSNSAYKEMQTTLKSSERSSSTSAESHIQPVQKKSKNRTNCDINIHYKSGVCNTMRAKFYSVAQEAGFCLQDKMEILMKRQEERGIQKFRAFVLVSNFQKDIAKMRHHISVVKGDAEEIADHWYFDLLSKLPEDLKNFRPAKKILVKLQKFGENLDLRIRPHVLLKVLQDLRIWELCSPDIAVAIEFVREHIIHMPQEDYISWLQSRINIPIGPYSALR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.******* .. *: * .:::* *..**. *. * :**** ******:*******.******** :*:**.* **:** *:**:*** ******:* *:*: *.**:**: **:*.* * : *******.*:::***.*:**:*************************:*:*:*************************:*:**:*******:* *::* ::.********:***:*:**********:****.**** .**************:** *:: ***************: :*. :*:*******::** **: .:*: *** *******:**.***** *****.*.* ** *: *:*:*..*****:***************** *******:***::*::.*******:****::*:*******:*****************.******** ******************************************************:.*****:*:*: . * ", "identical_positions": 400, "similar_positions": 97, "identity": "72.33%" }, { "cls_id": "homologset.agr.MGI:2141070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A140UHX9-1", "uniprot_id": "A0A140UHX9_RAT", "id": "A0A140UHX9-1", "name": "", "aln": "--MAAAAAGTG--TWAAQEKQFPPALLSFFIYNPRFGPREGEEENKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPSKPAKSLHTQKNRQFFNEPEENFWMVMVVRNPIIEKQSKDGKA-VVEYQEEELLDKVYSSVLQQCYSMYKLFNGTFLKAME-----DGGVKLLKERLEKFFHRYLQTLHLQS-CDLLDIFGGISFFPLDKMTYLKIQSFINRMEESLSVVKYTAFLYNDQLIWSG-LEQDDMRILYKYLTTSLFPRHIEPELAGRDSPVRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFP-----KIFVNTDDTYEELHLIVYKAMSAAVCFMIDAS-TQLTLDFCRRLDSIVGPQLTVLASDICEQFNINKR-ISGSEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLTSVHPDLMKILGDINSDFTRADED----EEIIVKAMSDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1Y8-1", "uniprot_id": "CCZ1_MOUSE", "id": "Q8C1Y8-1", "name": "Vacuolar fusion protein CCZ1 homolog", "aln": "--MAAAAAGPG--AWAAQEKQFPPALLSFFIYNPRFGPREGEEENKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPSKPAKSLHTQKNRQFFNEPEENFWMVMVVRNPIIEKQSKDGKA-VVEYQEEELLDKVYSSVLQQCYSMYKLFNGTFLKAME-----DGGVKLLKERLEKFFHRYLQTLHLQS-CDLLDIFGGISFFPLDKMTYLKIQSFINRMEESLSVVKYTAFLYNDQLIWSG-LEQDDMRILYKYLTTSLFPRHIEPELAGRDSPVRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFP-----KIFVNTDDTYEELHLIVYKAMSAAVCFMIDAS-TPLTLDFCRRLDSIVGPQLTVLASDICEQFNINKR-ISGSEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLTSVHPDLMKILGDINSDFTRADED----EEIIVKAMSDYWVVGKKSDQRELYVILSQKNANLIEVNEEVKKLCATQFNNIFFLD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86791-1", "uniprot_id": "CCZ1_HUMAN", "id": "P86791-1", "name": "Vacuolar fusion protein CCZ1 homolog", "aln": "--MAAAAAGAGSGPWAAQEKQFPPALLSFFIYNPRFGPREGQEENKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPSKPAKSLHTQKNRQFFNEPEENFWMVMVVRNPIIEKQSKDGKP-VIEYQEEELLDKVYSSVLRQCYSMYKLFNGTFLKAME-----DGGVKLLKERLEKFFHRYLQTLHLQS-CDLLDIFGGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSG-LEQDDMRILYKYLTTSLFPRHIEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPDAKCRFP-----KIFVNTDDTYEELHLIVYKAMSAAVCFMIDAS-VHPTLDFCRRLDSIVGPQLTVLASDICEQFNINKR-MSGSEKEPQFKFIYFNHMNLAEKSTVHMRKTPSVSLTSVHPDLMKILGDINSDFTRVDED----EEIIVKAMSDYWVVGKKSDRRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P86790-1", "uniprot_id": "CCZ1B_HUMAN", "id": "P86790-1", "name": "Vacuolar fusion protein CCZ1 homolog B", "aln": "--MAAAAAGAGSGPWAAQEKQFPPALLSFFIYNPRFGPREGQEENKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPSKPAKSLHTQKNRQFFNEPEENFWMVMVVRNPIIEKQSKDGKP-VIEYQEEELLDKVYSSVLRQCYSMYKLFNGTFLKAME-----DGGVKLLKERLEKFFHRYLQTLHLQS-CDLLDIFGGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSG-LEQDDMRILYKYLTTSLFPRHIEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPDAKCRFP-----KIFVNTDDTYEELHLIVYKAMSAAVCFMIDAS-VHPTLDFCRRLDSIVGPQLTVLASDICEQFNINKR-MSGSEKEPQFKFIYFNHMNLAEKSTVHMRKTPSVSLTSVHPDLMKILGDINSDFTRVDED----EEIIVKAMSDYWVVGKKSDRRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803R2-1", "uniprot_id": "CCZ1_DANRE", "id": "Q803R2-1", "name": "Vacuolar fusion protein CCZ1 homolog", "aln": "MLMISPRMASG-----MQEKQYTPSLLSFFIYNPKFGPREGEEEKKILFYHPIEIEKNEKIRNVGLCEAIVQFTRTFCPTKPAKSLHTQKNRQFFHEPEENYWMVMVVRNPMVEKPNKDGKPPTVEYQEEEIIDSVYGSVLQQCYSMYKLFNGTFSRAFE-----AGGVELLTQKLEKFFYRYLQTLHLQS-CDLLDVFGGISFFPLDKMTYLKIQSFVNRVEESLSLVKYTAFLYNDQLIWSG-LEQDDMRILYKYLTTSLFPRHTEPELAGRDSPLRPEVAGNLLHYGRFLTGPANLKDPEAKFRFP-----RIFVNTEDSCEELHLIVYKAMSAAVCFMINAS-VDLNREFCEKLDSLVGPQLTLLASDICEQYNINRR-ISGPEKEPQFKFIYFNHMNLAEKSTIHMRKMASVSLTSVHPDLMKILGDINCDFARVDED----EEIIVKAMTDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKRLCATQFNNIFFLD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZL5-1", "uniprot_id": "CCZ1_DROME", "id": "Q9VZL5-1", "name": "Vacuolar fusion protein CCZ1 homolog", "aln": "--------------MAKLLQRVEITLRSFYIFNSTFGQVEGEEHKKVLFYHPNDIELNTKIKDVGLSEAIIRFTGTFTSEDDCQALHTQKTTQLFYQPEPGYWLVLVLN--VPKEVRLKEGVEVADYRGAEISDRIYRAILRQCYQMFRFQNGCFSSCGSEEPNPDKRRELLCQKLLQFYDQHLTNLRDPAQCDIIDMLHSIQYLPLDKTLFLRAQNFG-TLCETFPDIKESIMLYQEQVLCGGKLSPEDLHCVHSYVVQHVLKVEASSSTIAVSPSLKRSIS--ECQVGGFVRSRQKVAGDEHDAVNEEDHPMKVYVTLDKEAKPYYLLIYRALHITLCLFLNADQVAPKQDLYDDLHAYMAPQLTSLARDISSELTKEAVGAAGQDNSSGNSETAPKYLFINEQSLQHHTNFQRHLPQGLPRNVLSIIADLANGSGKAEMESAPAEEVQVKTTNDYWIVKRRCNYRQYYVILCNSKATLLDVTQEARRIFEQELTDDVFFDK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* **:*:*. ** **:*.:*:***** ::* * **::***.***::** ** . . .::*****. *:* :** .:*:*:*:. : :: . . :*: *: * :* ::*:***.*::: ** * . . :** ::* :*: ::* .*: : **::*:: .*.::**** :*: *.* : *:: :* : :**::*:: .* *. :*:: ::.*:. :: . ... . ...:: .:. : * *: . :: . : . :::*. :. : :*::*:*: ::*::::*. . . :: *.: :.**** ** **..: . : :* ::.. . ::: : *:* * : .: :::.*:.*: . :.: : **: **: .***:* ::.: *: **** :.:*.*::*.:*.::: ::.: .*:* ", "identical_positions": 122, "similar_positions": 198, "identity": "24.21%" }, { "cls_id": "homologset.agr.MGI:2141101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61460-1", "uniprot_id": "DEPD5_MOUSE", "id": "P61460-1", "name": "GATOR1 complex protein DEPDC5", "aln": "--------------------------------------------------------------------------------------MRTTKVYKLVIHKKGFGGS---------DDELVVNPKVFPHIKLGDIVEIAHPNDE------YSPLLLQVKSLKEDLQK----ETISVDQTVTQVFRLRPYQDVYVNVVDPK--DVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEF--AGIRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEINRASIQEDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAGG---FPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGK-------KSASEKTKNGRDTSLGTPKESENTLPIQVDYDAYDAQVFRLPGPSRAQRLA------------TCRSVREQENHSRKSASSCDVSSSPSLPSRALPTEEVRSQASDDSSLGKSTNILMIPNPHLHQYEVSSSLGYTS-TRDVLENMIEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGP-----------SGEAIQIHHQTRQNMAELQGSRQR--------------DPTHSSAELLELAYHEAAGRHSTSRQ-----------------------------PGDSMS-LNFSGT-EELSVSLLSNSSTGVNPRT-----QNKDSLEDSVSTSPDP---------MPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEAD----MDRRDEEGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLSSSPLYSRGLVSRNRPEEE-GQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYS-LCPSHSDSEFVSCWVDFCHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEVHCDIYGDKPRADED------EWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSLGEQQ-TTVHG-KSSTQPAENSSVAMTPTYVDSPRKDGAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTGQPMDRGNNQTFGNSQNI-EQAFPSANSGDYSSQQHVASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLS--PCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVMDKEPERVAMQQP---SAPWYTAGADDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLSCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSVS-AFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSS----TNQNMF-CEERVGYNWAYNTMLT-KTWRSSATGD----EKFADRLLKDFTDFCINRDNRLVTFWTNCLEKMHASAP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YBC5-1", "uniprot_id": "A0A8I5YBC5_RAT", "id": "A0A8I5YBC5-1", "name": "GATOR1 complex protein DEPDC5", "aln": "--------------------------------------------------------------------------------------MRTTKVYKLVIHKKGFGGS---------DDELVVNPKVFPHIKLGDIVEIAHPNDE------YSPLLLQVKSLKEDLQK----ETISVDQTVTQVFRLRPYQDVYVNVVDPK--DVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEF--AGIRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEVNRASIQQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAGG---FPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGK-------KSATEKTKNGRDTSLGAPKESENTLPIQVDYDAYDAQVFRLPGPSRAQRLA------------TCRSVREQENHNRKSASSCDVSSSPSLPSRALPTEEVRSQASDDSSLGKSTNILMIPNPHLHQYEVSSSLGYTS-TRDVLENMIEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGP-----------SGEAIQIHHQTRQNMAELQGSRQR--------------DPTHSSAELLELAYHEAAGRHSTSRQ-----------------------------PGDSMS-LNFSGT-EELSVSLLSNSGTGMNPRN-----QNKDSLEDGVSTSPDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEAD----MDRRDEEGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPSTTVPPPLSSSPLYSRGLVSRNRPEEE-GQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYS-LCPSHSDSEFVSCWVEFCHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEVHCDIYGDKPRADED------EWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLESTGPPVGKKGTSALSALLEMEASQKSLGEQQ-TSVHG-KSSTQPAENSSVAMTPTYVDSPRKDGAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTCQSVDRGNNQTFGNSQNI-EQAFPSTGSGDGSSQQHIASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLS--PCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLIAHASGEAWRTFVYGFYFYKIVTDREPERVAMQQP---SAPWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLGCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSAS-AFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSS----TNQNMF-CEERVGYNWAYNTMLT-KTWRSSATGD----EKFADRLLKDFTDFCINRDNRLVTFWTNCLEKMHASAP--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75140-10", "uniprot_id": "DEPD5_HUMAN", "id": "O75140-10", "name": "GATOR1 complex protein DEPDC5", "aln": "--------------------------------------------------------------------------------------MRTTKVYKLVIHKKGFGGS---------DDELVVNPKVFPHIKLGDIVEIAHPNDE------YSPLLLQVKSLKEDLQK----ETISVDQTVTQVFRLRPYQDVYVNVVDPK--DVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEF--AGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEG---FPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGK-------KPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLT------------TCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHLHQYEVSSSLGYTS-TRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGP-----------SGEAIQIHHQTRQNMAELQGSGQR--------------DPTHSSAELLELAYHEAAGRHSNSRQ-----------------------------PGDGMSFLNFSGT-EELSVGLLSNSGAGMNPRT-----QNKDSLEDSVSTSPDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEAD----IDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE-DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYS-LCPSHSDSEFVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADED------EWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQ-AAVHGGKSSAQSAESSSVAMTPTYMDSPRKDGAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLS--PYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQP---ATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSAS-AFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSS----TNQNMF-CEERVGYNWAYNTMLT-KTWRSSATGD----EKFADRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QKY4-1", "uniprot_id": "A0A8M9QKY4_DANRE", "id": "A0A8M9QKY4-1", "name": "", "aln": "----------------------------------------------------------------------------------MTVTMKANKSYKLVVHKKGFGGS---------DDELMMNPKVFPQVKLGDIVEIAHPNDE------YSPLLLQVKSLKEDLQK----ETISVDQTVAQAFKLRAYQDVIINIVDPK--EVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYVTQKVEF--AGIRAQASELWVKGEKVTCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLSDLFAKWKEKNCSHEVTVVLFSRTFYSAKTLEEFPESQRASVRQDHEGRYYEDFYRVVAQNERRDEWMSLLVTIKKLFIQYPVLVRLKGADG---FPCGHNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRTVHGDSRIGDDYNLPHWINHSFYTSKSQNSCSCFTPRIKLAGK-------KVHAEKAKNSKEHSLGAPKDAENSLPIQVDYDAYDSQVFRLPGPSRAQRSTNFSSSHINS-TDSNRSSRERESVSRKSWGSADVGSSP--PNRHTGPDEQRSLASDDS-LGHMSNILLIPRPAQGQYEVSSSLGYTSCTRELLEKMVES-QRDSSAPGRFTVGSAESTLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGP-----------SGEPIQIHHQTRQNMAELQGSEQR--------------DPARTSAELLELAYHEATGSKRTASR-----------------------------HAGENG-LYISGVPDNISGSPASSSSTGTP--------VNRGSFED-YSGSLDPILLLSAPPTVPSFCCTVGVDWKSLTTPACLPLTTDYFPDRQTLQNDYTEGCYDLLPHTD----LERRDDETPVMTAHQVFEEFICQRLMQGYQIIVQPNR-KPQPAIAPPLSSSPLYSRGLVSRRKPEEEESLYWLSMGRTFHKVCLKDKIITVTRYLPKYPYESTQIQYSYN-LCPPHADAHFMPFWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIDSLKFWRTRFLLLPAG--GARRVADGEGHWDVYGEGAGAGRDGLAGTGDWTLLDGFIRFLEGLNRIRRRHRSDRMIRKGATIKGLQVTGALTSYTPEPIAPPLGKKGTSALSALLELEQTQKTFEEQQLAAQHGGKPCGPFSEAANVALTTTFVDSPRKDAAFILDFIRSPR-SSYICHSQLPAEQVPANPIEGGLSDKISNQPGERTSAASQATGDPTPGASLETGGQSGSS-----GLSLSSSSTLMEILEAIKHPTTGVQLLPEQRGLP--PNCFVSAEVVHWLVSTVENVATQGIAVEIMQKMLEEGLITHASGDAMRTFVYGFYFYRIVDKDNEKAPLTQLPPAGANVWSAAALEDFALFQRKWFEVAFVMEERRPCDLPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQKTVTLDVDVNNRSDRTEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKAASCGFLLVPVLEVPFALSSYLYGDPLRAQLFIPLNIQCLLKEGSDNLFEGFEPETYWDRMQLFQEAILTRFGFVQDKFSAS-AFNFPSENKPQYIHVTGTVFLQLPYSKRKYSSGQRRRRNSTTS----TNQSLFGSEERVGYNWAYNTMLT-KAWRTGVLGD----EKLADRLLRDFTDFCANKDNRLVTFWESCVEKMNASAP--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0E3-1", "uniprot_id": "IML1_DROME", "id": "Q9W0E3-1", "name": "GATOR complex protein Iml1", "aln": "-----------------------------------------------------------------------------------------MKLYKLNTHTRGCNKSY--------DADLVMNLKDHPNANVGDVVEIYAPDEEN-----GTHLLLQITEFNGSCGR----DVISIESGIANAFKMRPYSNVVMRIVKPA--DVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNERCDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNSSATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTS--ADDYSLPHWINLSFYSTNKKIVYSSFIPRIKLPLFGSQLTLHDGVGDGEGEENERHFLSCNQSEYKHNSLFDYDAYDEQIFQP--------------------------LPAQSTCSLQRVVRAKKTSVPSLETYAYRNND-------------WENLTPTQIPAMRRKMSDPDIHHGT---SAMLAALQPDTTNLSESLASEKNSRRTIVSIAP-IVRPGRALINPFDPSQVTIKLTSNRRRWTHIFPKGP-----------TGVLIQQHHYQAVPAKPTQAGQQRPLQQTQSNNNNDQEDYGCENGEQYDRVSSHSLLNKSDSSQSFVMGDEPIDFFKRRQNSPMNPQPANVPNLTATQAKSYLWGATGEQEWTPAITTVKHLRPIV-----EGEHHHLGSLEALRALDPPPDAEAGGGRGKIIIGVDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEK--------PPTASGCSSGSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYR-FHAPQHET-YEISGVNFTTEKLENFNWNHMDLYICTRGDVDYPLMESLKYWRYRMYLLPRENIVSKIASCQR--CDIFPDVTADNTR--------EQVEDFVRLIEAVSKLKR-----QYARKARYLASLLQDSPIAHITKRRHS-----------TSIISRPQPNQGLTNSPFRERVG--SNRLPEKRPSINVRPKLENG--------------------------RIPRIFPATDAAAAAGVAARDDQDDGFP---------------------------VDIKFSPNATLPEIFEAMKHPVNGVGFFSQTQSLP--SCTFVSYDALMWLKTRLN---NGRHPLDLLEAMRKERMICHASGDWKKPVVPGFVFYYVVQQDK------------NAKDYAPPLDDYSAFVNEWLEIEFQGCSFLWHDEP-------VTTPVPNFLRDSPAPQSWTETS-------SNKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVS-VPADPMAEPFTKKSDPLRGPIFIPLCTTFLPN--GAALFDEFPEESRSDRMLFFQEAILGKFGFLPCVLEKKYSVGKDLPKEYQYVHCTGNMFALIRCATNNYQVESPILKEANVTRCVYGHTNNTNVPKKVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFWTQSQELKRRAQKFEFNNNNTEENKMK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47170-1", "uniprot_id": "IML1_YEAST", "id": "P47170-1", "name": "Vacuolar membrane-associated protein IML1", "aln": "MFAKLHGKKQRPISSINSQTPRTSNTTHANSISLSSGNLIVGSNRNLRQKKEQFGSQQRASGRKLISNKENDDNVNNGGDNNYDNGERVHRHHIPGLKIKAYQAELGYHESRFSENLVMLNLVEFPDIKPGDLVELKTYHKNPSASNGDKKIYFIAKDFDGETKRRAKTSNVSILSGQLQTLLDLPSRSRIWIKLKPNKFDLQADVVEFNIKDCLLNRGDMWVLSSKLVDTCVFMDQRLAF-LDSIRGTIKGIYRNGKKIVSGYIGEQTRIIFRSESARLIFLIQITDEMWNFEETGEQLFQKMVNSFFPKIFKKWKDVDTHHTITIAFAISMDLSDTSFKDLTP--------GESLKNSQDYFRIVVDQVSIIHWVDIMETLREEFMEIRKDLLNKQTDKGYSVANGRFSPVIKSNFLELVNFATTILTDPFKQLDLRHTTTHVMIISPGSGLFDVDYSLLRLTGKKLLSLEMTMDLICLSKAPLHIVPLFRYRDFEN------KLHHCVPLWLSVFFWNDHDKKSNSEWTPRCKIYDLQMMG-ITENELIREVDVEYLQLNKKVKSLSEFMNDYDKNAFEVKILCAGSNTKQSKKLNSKFDTVFENDVVVKARKIPATATTTHGNTKFIWRGPKVALPAIKDIQKPNVIPDLSIKTIEASFYDDCNTTNDKISTPTTSNNDNLEMNDSLVSVRSADNQNTSLALDSLKGLSKRNSLKDFTQRVITKFISNIDTSKNKKIKSTLLRDDVDNSPLGSNTPLPSSESKISGLKLQQKGLADENVISKRGNLIIKKN---------LSIFGLPSNEIMSGSPSSYLGSSHTRTSS-------------------------KLSNMSDKAAFITEGQKSKHDDSNTYSLTQQLKHRISETWVDIKSPSIPVSSEFANELLPIRWKDVWPKYVARKYSKWRSFTTPAELPITISDFPSKDDFDRNFIFRNHSVTLNTD---------QEQYNQTYKDLLRDMIYMRLLTGFQICVGRQVEKIELSRESGESETVVNKYLDFNQN---DAFKLYLMIDSEIHRITCSSSGIIDVERYLRKDEANLFDQVPSYIPLVKTRYESSFRDAMIDPLHVKRESLNWNQIDQVLAGYG--DNLIDRKWHGFRAKYVVLPTDIPPNTYSMVINGKSETLNPEE-------------IRVEGLRRLIGSITRSRLRTEKEKKGRKTKREE--------------------------IQPEVMFYTGPLYNFINEQ----------QTSLESSAINFKDSIFVND---------------------------------------------------------------------------------NNLLNRNVELSKLAYQIQRGEDRITLVNRKWHWKKHEKCFVGSEMVNWLIRNFSDIDTREDAIKYGQKVMKEGLFVHVLNKHN--FLDGHYFYQFS---------------------PEYVMDTNKLEKTNSHRSTLSDPKQMLRKASTGSSNDPSAMTPFSSVVPAISASNASVADAKEPSRPILMLSNSLVIDVDPAGKSSKQESCTVHYDRVHNPDHCFHIRLEWLTTTPKLIDDLVGNWSRLCERYGLKMIEIPWEELCTIPSVN--PFHSFVEIKLAINPWEDP------EFKDRELFAKSKFYYHVYLLKASGFLLDNRASKFLQNQDIEFDIMYSWGK-PQFKYVQYIHHTGAYVAELRE----------NGCLFLAPNNIYISRVNPGNIIGKIHSASSSSLD------AQKVILNFKSTCLDYQKLRSIFLDAKEMWITGKIVED------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. . : :::* .*. : **:**: ..: . : : ..:. . : . :*: . :.: . . :.* :: * :*:.:** :.*.:** *.. *..**.:: ::: : ** :: :.::: .* * *:*:::*** :: : :::*:: ***:*: *: *:* **.*:..:* **:. . * :*:.: .:..::. . . : :*::::. :: .* :: ::: * . : .. . *. :.*:** :*:: . : . : : : :* ::*:** *:*.** * :* ::::. : **:*:.: *** ***:: :: .: :* *:. *:. :.: . : ** *: . : . : .: * :*:: ::: . . * : .: . : . . . :.. : : . . : :*. : .*: :: * . * *. :* :* : :.. . * . . * : . . . . .*:*:* ** **:* . **.: ::.:: : : . : .:: .::: ** *:*: * : . :. . : * : .. .: .. :* * * : : * : .: :: : :: : *. :** :* :. * * : . : :* : :** . : ::.: *:: .:.: : : ** . :: . : :. : . : . . . :. . * :: ::: : :. . *:. : : ** .. . :. : : :* :: *. .. .: *. ** . . * : . . . : .. .. . * : . . :::* ::.: * :. . .*.* :.*:: : :: ::: .* * . .: : : :. *::. : * * . : * . :: : **: . . . * . * : .. . : :.: . : * : . ::: :* . * : :: * ", "identical_positions": 151, "similar_positions": 424, "identity": "8.22%" }, { "cls_id": "homologset.agr.MGI:2141135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3A0-1", "uniprot_id": "HSC20_MOUSE", "id": "Q8K3A0-1", "name": "Iron-sulfur cluster co-chaperone protein HscB", "aln": "--MWGCGARALLG-----------VWEVRLAGFLGRRLLG----------------SNAAAGK---------SIAPQCWNCGHAREAGCGDEFFCSHCRALQPPDPTRDYFSLMNCNRSFRVDVTKLQHRYQQLQRLVHPDFFSQKSQTEKHFSDKHSTLVNDAYKTLQAPLTRGLYLLKLQG-----IEIPEGTDYKADSQFLVEIMEINERLADAQSEAAMEEIEATVRAKQKEFTDNINSAFEQGDFEKAKELLT----KMRYFSNIEEKIKLSKTPL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A2K9-1", "uniprot_id": "A0A8I6A2K9_RAT", "id": "A0A8I6A2K9-1", "name": "", "aln": "--MWSCRARSLLC-----------VWEVRLARFLGRSLLS----------------SNAASGK---------SIEPQCWNCGRAMGAGRGDEFFCAHCRALQPPDPTRDYFSLMNCNQSFRVDIRKLQQRYQQLQRLVHPDFFSQKSQTEKRFSEKHSTLVNDAYKTLQAPVSRGLYLLKLQG-----IEIPEGTDYRTDSQFLVEIMEINEKLADAKSEAAMEEVEATVREPSFCNEQPWGSEVAAPALPLALPLLQYDGMEMFSFSWLASHYWFSKHLLNRKNLRTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWL3-1", "uniprot_id": "HSC20_HUMAN", "id": "Q8IWL3-1", "name": "Iron-sulfur cluster co-chaperone protein HscB", "aln": "--MWRGRAGALLR-----------VWGFWPTGVPRRRPLS----------------CDAASQAG--------SNYPRCWNCGGPWGPGREDRFFCPQCRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKHSTLVNDAYKTLLAPLSRGLYLLKLHG-----IEIPERTDYEMDRQFLIEIMEINEKLAEAESEAAMKEIESIVKAKQKEFTDNVSSAFEQDDFEEAKEILT----KMRYFSNIEEKIKLKKIPL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V1J6-1", "uniprot_id": "B0V1J6_DANRE", "id": "B0V1J6-1", "name": "Iron-sulfur cluster co-chaperone protein HscB", "aln": "-MITLHRLRILLKTPGFKHTYACISNEQRLNIVLTPCLASGRAVSSYSKDFKDVCHSNAAKGRLTLNSFSTVTVNRVCWNCG-----ASADLFFCAFCKVIQPPDNKTSYFDILKCEENFSLDTQKLQQKYVKLQRVLHPDNFTQKSQKEQEYSEEQSALVNKAYRTLQKPLSRAVYMLELRG-----VLLEEGTDATADPALLLEVMEINESLAETRSQDEVSAIGRSVQEKLKDLTERMNSSLNRGDLLAAKMLLN----KMKYFTNIQEKVKDRITQGC-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNT7-1", "uniprot_id": "A8JNT7_DROME", "id": "A8JNT7-1", "name": "", "aln": "MSRVINGFKSAVKATN-------YTPLVRNAAQFNQFQLP-----------------EIRKFS--------VESSPACWNCQK--KSELKQNMICSDCGHLQDVNSGINYFKLLSFPIQFSLESQKLTRSFRQLQTIVHPDKYSNKTSREQTNSSDWSSLINKAYKTLSTPIDRGQYLLQLEG-----EQMPQ-DNSALNKEFLMAMMERNEEVEDAEDTQTLENLNIQLIKELEEMARKLNALFDSKDLSGVKETLV----EMKYLLSIQNSIKQKQQSLLGS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53193-1", "uniprot_id": "JAC1_YEAST", "id": "P53193-1", "name": "J-type co-chaperone JAC1, mitochondrial", "aln": "----------------------------MLKYLVQRRFTS---------------------------------------------------TFYELFPKTFPKKLP------------IWTIDQSRLRKEYRQLQAQHHPDMAQQGS--------EQSSTLNQAYHTLKDPLRRSQYMLKLLRNIDLTQEQTSNEVTTSDPQLLLKVLDIHDELSQMDDEAGVKLLEKQNKERIQDIEAQLGQCYNDKDYAAAVKLTV----ELKYWYNLAKAFKDWAPGKQLEMNH--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: :* : : :** *** : : . *: :*.**:** *: *. *:*:* . : :*: ::: :: : : . :. : . . :: : . ", "identical_positions": 18, "similar_positions": 41, "identity": "6.23%" }, { "cls_id": "homologset.agr.MGI:2141142", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0E6-1", "uniprot_id": "RPAP2_RAT", "id": "Q5I0E6-1", "name": "RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPYSLGPSARASSTHR-VATGTKQTSALKRRDASKRQAELEAALQRKVESERRAVRLVEQLLEENIT-EEFLKECGMFITPAHYSDVVDERAIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITER---KSFCSNFCYKASKFFEAQIPKTPVWVREEERPPEFQLLKKGQSGCSGEVVQFFRDAVTAADVDAYGAFDAQCEPASSSTWSERASDERASDEEGPGFVSSLLP--------GNRPKAVGTKPQPHRQSSTVKKKAAQKMTSKHG--EQTVSEVTEQLSNCRLDS--QEKVATCKLPAKKENTQISSPGPLCDRLNTSTVSENKHSVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVQVRPEVAKANLLRVLKDTLTEWKTDETLKFLYGQDHGSVCLQPSAASGPDEELDEDDISC----------QAQNTLDETLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDSTKSQDSKENELQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLVQTFRLSNRNIIHKPVEWTLIAVVLLSLLTPILGIQKHSPKNVVFTQFIATLLTELHLKCEDLENLAMIFRTSC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC34-1", "uniprot_id": "RPAP2_MOUSE", "id": "Q8VC34-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPCSLGPSTRASSTHR-DATGTKQTRALKRGDASKRQAELEAAIQRKVEFERKAVRIVEQLLEENIT-EEFLKECGMFITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITER---KSFCSNFCYRASKFFETQIPKTPVWVREEERPPDFQLLKKGQSGSSGEVVQFFRDAVTAADVDGSGALEAQCDPASSSSWSERASD-----EEEQGFVSSLLP--------GNRPKAVDTRPQPHTKSSIMRKKAAQNVDSKEG--EQTVSEVTEQLDNCRLDS--QEKVATCKRPLKKESTQISSPGPLCDRFNTSAISEHKHGVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVHVRPEVAKANLLRVLSDTLTEWKTEETLKFLYGQNHDSVCLKPSSASEPDEELDEDDISCDPGSCGPALSQAQNTLDATLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDTTKSQDSKESVLQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLIQTFRLSNRNIIHKPVEWTLIAVVLLLLLTPILGIQKHSPKNVVFTQFIATLLTELHLKFEDLEKLTMIFRTSC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXW5-1", "uniprot_id": "RPAP2_HUMAN", "id": "Q8IXW5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2", "aln": "MADFAGPSSAGRKAGAPRCSR-KAAGTKQTSTLKQEDASKRKAELEAAVRKKIEFERKALHIVEQLLEENIT-EEFLMECGRFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITER---KSFCSNFCYQASKFFEAQIPKTPVWVREEERHPDFQLLKEEQSGHSGEEVQLCSKAIKTSDIDNPSHFEKQYESSSSSTHSDSSSD------NEQDFVSSILP--------GNRPNSTNIRPQLHQKS-IMKKKAGHKANSKHKDKEQTVVDVTEQLGDCKLDS--QEKDATCELPLQKVNTQSSSNSTLPERLKASENSESEYSRSEITLVGISKKSAEHFKRKFAKSNQVSRSVSSSVQVCPEVGKRNLLKVLKETLIEWKTEETLRFLYGQNYASVCLKP-EASLVKEELDEDDIISDPDSHFPAWRESQNSLDESLPFRGSGTAIKPLPSYENLKKETEKLNLRIREFYRGRYVLGEETTKSQDSEE-------HDSTFPLIDSSSQNQIRKRIVLEKLSKVLPGLLVPLQITLGDIYTQLKNLVRTFRLTNRNIIHKPAEWTLIAMVLLSLLTPILGIQKHSQEGMVFTRFLDTLLEELHLKNEDLESLTIIFRTSCLPE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYY5-1", "uniprot_id": "RPAP2_DROME", "id": "A8DYY5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog", "aln": "--------------------------------MTTEKGEQLRQQLIAAVVKKRAAIARAHEIVVRLLEPGIP-EPEFLSLLCEIGPPNYSDIVDEREINKLCGYPLCSTVLENVPKQKYSISASKNKVYDITER---KKFCSGYCFKASEYIKSQVPTSPLWLRDRETRPSFQLLPRNT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0UYH6-1", "uniprot_id": "RPAP2_DANRE", "id": "B0UYH6-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase rpap2", "aln": "-------MDAGEVTRKSRPSKSKKKGGKGTQAISAEDEAKRREAVKEQLRQKLELERKARQVVERLLEDSVT-EEFLMDCAWHITPANYKDTVEERSIAKLCGYPMCPNKLTNVPTQQYKISTKTNKVYDITER---KCFCSNFCYKASKSFELQISKIPLWLRKEESPPEIKLMKQGDGGSSGQEIKLIDKPITEADIDNP----IEDIPESNKDLIQGENG-----DIEQDFVSSVVSNQHKQVHWGKLPKRDEVSEDAAEYSHSEHEQRINGENKDESESSQTPQPQKDTTDHPALEKNASEIEGTLELLNQDKSTQQEGENTSSSQP-ESDISVPVAGDLNITQVGMSKRSAAGLKG-LLKDHHKAKTASTAISQC-------LLERLRQAFIEWRTKETMIFLYGPDYASGMQLSTAGAWEEEQLDED-------------DLDEAEVGVRSAEGGPSRTSAPVPDVETLRKETEMLELRVREFYKGVCVLPEEVETAAVKETEHTQDSGKDPPLPLVDSHAQHQIQKRIVVEKLSHSLRDIVGPLRLTMSDVINDVNNLVRTFRFTNTNIIHKSPEWTLIAVVLLSVLTEVSPLLRESLASVSSLEYISCFMKELKLEDKDLHNLVLLFKPCVPIQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12378-1", "uniprot_id": "RTR2_YEAST", "id": "Q12378-1", "name": "RNA polymerase II subunit B1 CTD phosphatase RTR2", "aln": "---------------------------MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFCENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKS--------AAENSSDGFFIH-------SMYCNNYHSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDM-YSVSLLEELVGSEVPI--------------DTVKSLIT--------------------------------------------------------------------------------------------------SFKDL---------EFDDTYKNEPLPLDVYFGQLTTDEETCIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40084-1", "uniprot_id": "RTR1_YEAST", "id": "P40084-1", "name": "RNA polymerase II subunit B1 CTD phosphatase RTR1", "aln": "-----------------------------MATIEDIKETALIPFQKHRQLSMHEAEVITLEIIGLLCDSECKDEKTLKYLGRFLTPDMYQDLVDERNLNKRCGYPLCGKSPERIRDPFSMNDTTKKFLLENNPYAYLSHYCSKFHFRCSQFYQVQLSDEALFARTGVHLFEDPEQDKHDIDFKVTLFEELLREKASE--------------EDIKSLIS--------------------------------------------------------------------------------------------------GLKKLGLNPDSGTTEKDDTELEDDLSKWLAQIKIVENDNPSILGDFTRED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * : * : : * * * :: * * ****:* . .:. . . . :*. : :.* *:. .: * . ", "identical_positions": 16, "similar_positions": 26, "identity": "2.49%" }, { "cls_id": "homologset.agr.MGI:2141161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNP0-1", "uniprot_id": "A0ABZ3NNP0_RAT", "id": "A0ABZ3NNP0-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "MELPTDPPLYTLNQSEKYRKCSNIFPRVTIDGFSLVPPLFYLSLSERRLELPLAPSSSSSGPASVPCSQCGRACGRHGFPSPVNPTFLISVPGSLCLLAICGARAPWRMGPPLDVWDFSS-PLLSLWMNRFYIYMGCALGVTLWFCVQIIIKKQVTRSQEKSVPGAP-----DSSLSPQEKHTHVSGVKI---FYGSQTGTAKGFAVVLAKA-------VTSLDLPVAIINLKEYDPDDNLIGEITSKNVCAFLVATYTDGRPTESAEWFCK---WLEEAANDFRFGKTYLKGLRYAVFGLGDSAYRSHFNKVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHGSIEA-------DFTAWKTKFISR-----------------------LQALQRGE-KKGCG--------GDCKRGKCESAQHGP--GEVRSHPHGELHPGDAEEEEPCESSSEDEHGT---KGYQSLNSVVDVEDLGNIMNPVKREKREKAQPEEKVV-----VHRNSEKNE------DSEARAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHRNMIKQFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISTFLVTNAQFPEEIRNLTPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLQALSAKQ--QRTVYRLTLVKCWNVDELQAYAELVSLGSPDFIEVKGVTYCGES--AASSLTMANVPWHEEVVRFVRELVDLLP----DYEIACEHEHSNCLLIGHKKFKIGGEWWTWIDYSRFQELVLQYEESGGSKTFSSKDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJM7-1", "uniprot_id": "TYW1_MOUSE", "id": "Q8BJM7-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "------------------------------------------------------------------------------------------------------------MG-PLDVWDLS--PLLSLWMNRFYIYMGCALGLTLCICVQ-IIKKQVTRSQEKRVPGAP-----DSSLSPQKKQTHVSGVKI---FYGSQTGTAKGFAVVLAKA-------VTSLDLPVAIINLKEYDPDDSLIGEITSKTVCAFLVATYTDGCPTESAEWFCK---WLEESANDFRFGKTYLKGLRYAVFGLGDSAYRSHFNKVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHGSIEA-------DFTAWKTKFISR-----------------------LQALQRGE-KKACG--------GNCKRGKCESAQHGP--GEARPHPQGELHPGDAEEEEPCESSSEDELGT---QDYQSLTSVVDVEDLGNIMNPVKREKREKSHQDGKAA-----MQRNPEKTE------DGEGRAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHQNMIKQFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISSFLVTNAQFPEEIRKLTPVTQLYVSVDASTRDGLKKIDRPLFKDFWQRFLDSLKALSAKQ--QRTVYRLTLVKCWNVDELQAYAELVSLGNPDFIEVKGVTYCGES--AASSLTMANVPWHEEVVRFVRELVDLLP----DYEVACEHEHSNCLLIGHKKFKIDGEWWTWINYSRFQELVLQYEESGGSKTFSSRDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV66-1", "uniprot_id": "TYW1_HUMAN", "id": "Q9NV66-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "------------------------------------------------------------------------------------------------------------MDPSADTWDLFS-PLISLWINRFYIYLGFAVSISLWICVQIVIKTQGKNLQEKSVPKAAQDLMTNGYVSLQEKDIFVSGVKI---FYGSQTGTAKGFATVLAEA-------VTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCK---WLEEASIDFRFGKTYLKGMRYAVFGLGNSAYASHFNKVGKNVDKWLWMLGAHRVMSRGEGDCDVVKSKHGSIEA-------DFRAWKTKFISQ-----------------------LQALQKGERKKSCG--------GHCKKGKCESHQHGSEEREEGSHEQDELHHRDTEEEEPFESSSEEEFGG---EDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSG-----LFRNMGRNE------DGERRAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLKALAVKQ--QRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCGES--SASSLTMAHVPWHEEVVQFVHELVDLIP----EYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGASERGFDPKDTRHQRKNKSKAISGC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NUM6-1", "uniprot_id": "TYW1B_HUMAN", "id": "Q6NUM6-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B", "aln": "------------------------------------------------------------------------------------------------------------MDPSADTWDLSS-PLISLWINRFYIYLGFAVSISLWICVQIVIEMQG-------------------------------------------------FATVLAEA-------VTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCK---WLEEASIDFRFGKTYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEA-------NFRAWKTKFISQ-----------------------LQALQKGERKKSCG--------GHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGG---EDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSG-----LFRNMGRNE------DGERRAMITP--ALREALTKQ-----------------VDAPRERSLLQTHILWN-ESHRCMETTPSLACANKCVFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQ--QRTVYRLMLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCRES--SASSLTMAHVPWHEEVVQFVRELVDLIP----EYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKNKSKAISGC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08C92-1", "uniprot_id": "TYW1_DANRE", "id": "Q08C92-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "-----------------------------------------------------------------------------------------------------------MSGVLNDVRDYTEGYLQVLWQNRLYVYSTAAVLIGVWFTVNMLFKKKKMVHPVSPLASKSVK--KQEPASEAKKVIYVSGVKV---FYGSQTGTAKGFAKELAED-------VIAQGIQCEVIDMKDFDPEDRLAEECTSKIICVFLVATYTDGQPTESAEWFCK---WLEEASTDFRYGKTYLKGMRYAVFGLGNSVYVGHFNTVSKSIDKWLWMLSAARIMTRGEGDCNVVKSRHGSVQA-------DFQVWKGKFLNR-----------------------LQALAKGE-KKACS--------GNCKKASCKNKKKHK----EEAEDNHSLAEKNNSEEELMESSSDEESSS---EDEKSHGSVIDMEDLGNVMNHMKKAKQRMEEDEEDSQR----VKQNGERKSEC----EEERREMITP--ALRDSLTKQGYKLIGSHSGVKLRRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDPAEKIIQEAMENHRNMIRQFRGVPGVRPERFEEGLTVKHCALSLVGEPIMYPEINSFLKLLHQQNISSFLVTNAQFPEEIRSLVPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLRALGEKQ--QRTVYRLTLVKAWNVDELKAYADLIALGQPDFIEVKGVTYCGES--SASSLTMANVPWHEEVIYFVQQLANLLP----DYEIACEHEHSNCLLLANHKFKVDGEWWTWIDYERFQELIQQYEESGGTKNFSAMDYMAKTPSWAVFGAGERGFDPTDTRFQRKNKTKDISGC---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08960-1", "uniprot_id": "TYW1_YEAST", "id": "Q08960-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase", "aln": "----------------------------------------------------------------------------------------------------------------MDGFRVAG-ALVVGALTAAYLYFGGRFSIALVIIVGYGIYCNEASGGSQDSQEKLDLNKQQKKPCCSDKKIADGGKKTGGCCSDKKNGGGKGGGCCSSKGGKKGGCCSSKGGKKGGCCSSKKNIGDNENTATEVEKAVNYPVTVDFTEVFRKPTKKRSSTPKVFSKNSSSNSRVGKKLSVSKKIGPDGLIKSALTISNETLLSSQIYVLYSSLQGAASKAAKSVYDKLKELDELTNEPKLLNLDDLSDFDDYFINVPVENALYVLVLPSYDIDCPLDYFLQTLEENANDFRVDSFPLRKLVGYTVLGLGDSESWPEKFCYQAKRADHWISRLGGRRIFPLGKVCMKTGGSAKIDEWTSLLAETLKDDEPIIYEYDENADSEEDEEEGNGSDELGDVEDIGGKGSNGKFSGADEIKQMVAKDSPTYKNLTKQGYKVIGSHSGVKICRWTKNELRGKGSCYKKSLFNIASSRCMELTPSLACSSKCVFCWRHGTNPVSKNWRWEVDEPEYILENALKGHYSMIKQMRGVPGVIAERFAKAFEVRHCALSLVGEPILYPHINKFIQLLHQKGITSFLVCNAQHPEALRNIVKVTQLYVSIDAPTKTELKKVDRPLYKDFWERMVECLEILKTVQNHQRTVFRLTLVKGFNMGDVSAYADLVQRGLPGFIEVKGATFSGSSDGNGNPLTMQNIPFYEECVKFVKAFTTELQRRGLHYDLAAEHAHSNCLLIADTKFKINGEWHTHIDFDKFFVLLN----SG--KDFTYMDYLEKTPEWALFGNG--GFAPGNTRVYRKDKKKQNKENQETTTRETPLPPIPA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . *:* . : : : * : : . :: . . *. :: ..* : :.. :*: . : : .. : :::: : * **. . : . ** .*. :.: .. *: . .:. : ::. . : :: :. *:. **:* .. . . * . .. . . . : . . . . . . . * : :* : : :. . . . : . : : . * : *:: . . **** . * :. .: ::. * **** ******:.****** * .***..:* *::* .* *:::*::.* .**:*::****: .*** :.: *:***********:**.** :::**** *::*** ***.* :*.: *******:**.*: ***:****:****:::::.*. * * ****:** *** :*:.::.***:*: * *.******.*:. .* ...*** ::*::** : **: :. : .*::*.** ******:.. ***:.*** * *::.:* *: ** * *: **: :** **:** .* * :** **:*.* . ", "identical_positions": 192, "similar_positions": 206, "identity": "20.62%" }, { "cls_id": "homologset.agr.MGI:2141165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MK49-1", "uniprot_id": "A0A096MK49_RAT", "id": "A0A096MK49-1", "name": "Importin subunit alpha", "aln": "MPRAGPGGVFPPVNMATSEAPEERLKKFKYRGKEMSLRRQQRIDSSLQLRKSRKDEQALKRRNIGLFSSDVVSQALVK--EANLTLDDIIKGVNSSDTIMCLLATQAAREMLSQENNPPLDVIIEAGLIPKLVDFLKAAHLPNLQFEAAWALTNIASGTSEQTGVVVKEGAIEPLIELLCSPHLTVSEQAVWALGNIAGDCAEFRDNVISNNAIPHLINLISTNIPITFLRNIAWTLSNLCRNKNPYPPEDAVRQMLPTLCQLLLHHDNEILSDTCWALSYLTEGGKDYIHHVVTTGILPRLVELMSSSELNVLTPCLHTMGNIVAGTNEQTQMVIDAGMLKVLGQVLRHPKSSIQKLAAWVMSNVAAGPRHHVQQLILCNLLPVLVNLLRNAELKVQKEAVCTVANFATGASQSQLTLLAYS-GVLEPMLNLLTAPDMEVITVILDVISYLLQQIDDLEDKKRLCFQIEEVGGFEKIESLQHHHNSYISHSALNIIEKYLYE-EEDD-DILPKPGLRV------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0LLJ0-1", "uniprot_id": "IMA8_MOUSE", "id": "C0LLJ0-1", "name": "Importin subunit alpha-8", "aln": "--------------MATSKAPKERLKNYKYRGKEMSLPRQQRIASSLQLRKTRKDEQVLKRRNIDLFSSDMVSQALVK--EVNFTLDDIIQAVNSSDPILHFRATRAAREMISQENTPPLNLIIEAGLIPKLVDFLKATPHPKLQFEAAWVLTNIASGTSEQTRAVVKEGAIQPLIELLCSPHLTVSEQAVWALGNIAGDCAEFRDCVISNNAIPHLINLISKGIPITFLRNISWTLSNLCRNKDPYPSESAVRQMLPPLCQLLLHRDNEILADTCWALSYLTKGGKEYIHHVVTTGILPRLVELMTSSELSISIPCLHTIGNIVAGTDEQTQMAIDAGMLKVLGQVLKHPKTSIQVLAAWTMSNVAAGPRHQVEQL-LCNLLPILVDLLRNAELKVQKEVVCTVINIATGASQDQLTLLAHS-GILEPMLSLLSAPDLEVVIIVLDIISYLLQHIDNLQEKKRLYFQIEKFGGFEKIECLQHHHNISISNSALDIIEKYFCE-DGDG-DSLPGPGLRV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9QM74-1", "uniprot_id": "IMA8_HUMAN", "id": "A9QM74-1", "name": "Importin subunit alpha-8", "aln": "--------------MPTLDAPEERRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCPDTPSEKTAKGVAVSLTLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFATGATMDQLIQLVHS-GVLEPLVNLLTAPDVKIVLIILDVISCILQAAEKRSEKENLCLLIEELGGIDRIEALQLHENRQIGQSALNIIEKHFGE-EEDESQTLLSQVIDQDYEFIDYECLAKK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52295-1", "uniprot_id": "IMA_DROME", "id": "P52295-1", "name": "Importin subunit alpha", "aln": "--------------MSKADS-NSRQGSYKANSINTQDSRMRRHEVTIELRKSKKEDQMFKRRNINDEDLTSPLKELNGQSPVQLSVDEIVAAMNSEDQERQFLGMQSARKMLSRERNPPIDLMIGHGIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGNIAGDGAAARDIVIHHNVIDGILPLINNETPLSFLRNIVWLMSNLCRNKNPSPPFDQVKRLLPVLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLPRLGLLLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVTNTTTSGTPEQIVDLIEKYKILKPFIDLLDTKDPRTIKVVQTGLSNLFALAEKLGGTENLCLMVEEMGGLDKLETLQQHENEEVYKKAYAIIDTYFSNGDDEAEQELAPQEVNGALEFNATQPKAPEGGYTF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. .: :.* .:* .. : . * :* :::***::*::* :***** : ..:::.:*: .:**.* : . ::**:*:*:*..**:.::* *::* : **: : . *******.*********:** *:: .*: :: ** * : :.************* . ** ** *.* :: **. *::***** * :*******:* * *:::** * :** :* ::*:*:******:*...: * ** :. :**** *: .* .: *.*:::****:**::**::.* :* * * :*:* *..* ***.:**::** :::: : .:: * :*.:.::*.***.. * * :*..: .*: * . :*:*::.** : * . : :: :* :: :. .:.* : :*:.**::::* ** *.* : :.* **:.:: : : : : * : ", "identical_positions": 171, "similar_positions": 175, "identity": "31.84%" }, { "cls_id": "homologset.agr.MGI:2141180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKQ3-1", "uniprot_id": "D3ZKQ3_RAT", "id": "D3ZKQ3-1", "name": "", "aln": "---------MAVEELQCIIKRCQILEEHDFKEEDFGLFQLAGQRCIEDGYINQLLEIIQDEKNKTIIKTMGWNLVGPVVRCLLR-GREEDKREECFLIFDLLVKLCNPKELLLGLLELIEEPSGKQISQIILLLLQPLQTVIQKLPNNKAYSAGLALSTLWSQLSLLPVPHSEEQIQADDYGLCQCCRALIEFTKPFVAEV---ASDKED-PANTKLKDELLKF------CFKSLKCPLLTAQFLEQSEEVGNDPFRCFASEIIGFLSQIGYPVPQIILNHGRKKRTWDYLEFEEEEDRQLADSVAALTYLVFVQGIGTDQLPMVLSPSYLLQLNMEHIEVLLQRTEQSVYSKGLELLETSLLRLEDNSLCYQYLEIKSFLAVPQGLVKVMTLCPIETLRKTGLAMLQLYIDKLDSQGKYTLFRCLLNTSNHSGVEAFVIQNIKNQIDLSYKKTHN-RWFAGAQLTSLLDLVLSLPEGAETDLLQNSDRIMASLNLLRYLVIKDNEDDNQTGLWTELGKIENNFLQPLHVGLNMSKAHYEAEIKNSQQNSQA-------ASMCKSVCSVTVGGEEIPTMPPEMQLKVLHSALFTFDLIESVLARVEELIEIKSKSTSEENAGMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZM1-1", "uniprot_id": "GLMN_MOUSE", "id": "Q8BZM1-1", "name": "Glomulin", "aln": "---------MAVEELQSIIKRCQILEEHDFKEEDFGLFQLAGQRCIEDGYINQLLEIIQDEKNKTIIKSMGWNLVGPVVRCLLR-GREEDKREECFLIFDLLVKLCNPKELLLGLLELIEEPSGKQISQIILLLLQPLQTVIQKLPNNKAYSVGLALSTLWSQLSLLPVPHSEEQIQADDYGLCQCCKALIEFTKPFVEEV---ISDKEN-KENAKLKDELLKF------CFKGLKCPLLTAQFLEQSEDVGNDPFRCFASEIIGFLSKIGHPVPQIILNHGRKKRTWDYLEFEEEEDKQLAESVASLTYLVFVQGIGIDQLPMVLSPSYLLQLNMEHIEVFLQRTEQSIYSKGLELLETSLLRLEDNSLCYQYLEIKSFLAVPQGLVKVMTLCPIETLRKKGLSMLQLFIDKLDSQGKYTLFRCLLNTSNHSGVEAFVIQNIKNQIDLSFKKTYN-KWFAGAQLISLLDLVLSLPEGAETDLLQNSDRIMASLNLLRYLVIKDNEDDNQTGLWTELGKIENNFLKPLHIGLNMSKAHYEAEIKNSQQNNQV-------ASMCKGVCSVTVGGEEIPSMPPEMQLKVLHSALFTFDLIESVLARVEELIEIKSKSTSEENVGIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92990-1", "uniprot_id": "GLMN_HUMAN", "id": "Q92990-1", "name": "Glomulin", "aln": "---------MAVEELQSIIKRCQILEEQDFKEEDFGLFQLAGQRCIEEGHTDQLLEIIQNEKNKVIIKNMGWNLVGPVVRCLLCKDKEDSKRKVYFLIFDLLVKLCNPKELLLGLLELIEEPSGKQISQSILLLLQPLQTVIQKLHN-KAYSIGLALSTLWNQLSLLPVPYSKEQIQMDDYGLCQCCKALIEFTKPFVEEV---IDNKENSLENEKLKDELLKF------CFKSLKCPLLTAQFFEQSEEGGNDPFRYFASEIIGFLSAIGHPFPKMIFNHGRKKRTWNYLEFEEEENKQLADSMASLAYLVFVQGIHIDQLPMVLSPLYLLQFNMGHIEVFLQRTEESVISKGLELLENSLLRIEDNSLLYQYLEIKSFLTVPQGLVKVMTLCPIETLRKKSLAMLQLYINKLDSQGKYTLFRCLLNTSNHSGVEAFIIQNIKNQIDMSLKRTRNNKWFTGPQLISLLDLVLFLPEGAETDLLQNSDRIMASLNLLRYLVIKDNENDNQTGLWTELGNIENNFLKPLHIGLNMSKAHYEAEIKNSQE-----------AQKSKDLCSITVSGEEIPNMPPEMQLKVLHSALFTFDLIESVLARVEELIEIKTKSTSEENIGIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GRH6-1", "uniprot_id": "A0AC58GRH6_DANRE", "id": "A0AC58GRH6-1", "name": "", "aln": "MNKAFRSISMALDQLSDMVQRCQTVKDESFAPEDYDLFTAAGSTCIEQGDSAQVLSILVDEKNQNIVRCMGWNLLGPLVKMLLK--KEDKTLPHCHAILLHLLEVCSPKELLVGLLEQVEEADSGSIAETITLLLKPLQTVLLRLGIRKASSVGMALSTLLSQVSRLPVPVTAEQEEDDVFGLCRCCSALLQFVKPFVEEIKEVVKDNNSISKDNELRVELLKF------CMKSLSEPLLEVQLKD-TDTLQRSPLRDFATEILIILSDIGESLPDLLSRNVLRRR--KVPGFLEEEVRYPKESLACMSHLLFVDHIAVDIFPAVFSPIFVLQCNMEYIELLLSRTEENRLQKGLELYEKSLVRVEENSLPVDLLELKTFFSVPQNLVKVMTMCPDQTLRTKGLKVFQLSIDKFNTEAKYKFFRGMLKTSHHAGVEGYIIKNIKNQIDSSLKPGNSNDWFLGKHLLPLLRLVLCLPQGPETDLLQNLDRIMESLNLLRYMLIRDKEWDNETGIWTELYKIEDNYLKPMRTGLNMSKAHYEAELRSTKENRKIGL-----KEAKASVCSVTVGNEKLPNMTPETQIQVLQSALFTFDLIESVLARIEEIIEAKDRPQS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BAD7-1", "uniprot_id": "A0A8M3BAD7_DANRE", "id": "A0A8M3BAD7-1", "name": "", "aln": "---------MAVNQLEDVIQKWRTIEE--FKPEDHELFLNAGHTCIAQGDGTLLLNFIKDEANKHIVRSMGGGLVPALVSEVLR---NGRSAVHCQAILSELVQICRVKEVLNTLLQQVDDADPNAIADSIIVLMPPIQSVLLRMSELKAPGLSMALDSLQKQISKLPVPYSNKQEQEDVYGLCRCCTAVLTFIQPFVQEV----KNQDTNSEATSLRAALLKLYVFTNVCMNSLREPLLQAQLDREGNKTEILPLWNFAAEIMAILVVIQESLPKILFYHPVRGK---EDDILEKQACHPNESKACIAYLLFVQLIAIDVFPAVFSPVFVLQCNMEYINLLLSRKDESWILKGLDLHVKSLERITACSLPVELLDLKPFHEVPQSLIKIMIECPIQHLRGRSLVVFQLFIEKLNGEAKHKFFRRIIKTSHHAGVESTILKNIKNQVEQTRKSVYQDGWFEGTRLISLLRDTICLPQGHETDLLHGMDRVMESLNLLRYLLIQKR--GISTGEWTDLCHIAETYTKLLRVCLSMSKSYYGTELKRLRENKKIKAKEFKEASGKRSVQSLIVKTETLGSMPPEAQDKVLQCALVTCDLMESLVVRIEEIIEESQK----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:::*. :::: : ::: * **. ** ** ** :* :*.:: :* *: *:: ** .*: .:* :* : . *: *:::* **:* **: :::.. *:: * :*: *:*:*: :: ** . .:**.:* .*:* **** : :* : * :***:** *:: * :*** *: .::: .*: ***: *::.* *** .*: : *: **:**: :* * ..*.:: : : : : *:: :* *.:::*:**: * * :* *:** ::** ** :*:::*.*.::. ***:* .** *: ** : *::*.* ***.*:*:* ** : ** .* ::** *:*:: :.*:.:** :::**:*:***. :::*****:: : * . ** * :* .** .: **:* *****:. **:* *******::*:.. . .** **:* :* :.: : :: *.***::* :*:: :: . .: *: * * : .*.** * :**:.**.* **:**::.*:**:** . : ", "identical_positions": 197, "similar_positions": 198, "identity": "31.57%" }, { "cls_id": "homologset.agr.MGI:2141183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M051-1", "uniprot_id": "F1M051_RAT", "id": "F1M051-1", "name": "", "aln": "----------MAADVFMCSPRRPRSRGRSVLLKPQVPEDDDDSDTDEPSPPPPSGVATSARAHASAAPLPPRAG----PGREEPPRRQQIIHSGHFMVSSPHR------EHPPKKGYDFDTVNKQTCQTYSFG---------KTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSS---LAQDDDMLYWHKHGDGWKT---------PVPMEEDSLLDTDMLMSEFSDTLFSTLS----------------SHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMD------------------------------TFEPFQELFSSSRSIFGS-----MLPPPTSVP-----APDPSSPPSQVEEAGEQTWQGNILPNPALPPVSLPN-----------------------------SLIASSAAPSLDPTEGQGCERTSQSVDPFIQP------ADFGPSEPPLSVPQPFLPVFTMTLLSP---------------GPAPAPVPTALPLVSPPAPTLNPPTPPAFLQTQTFAGVSTSSPVITHTASATLT-----HDASATTFSQSQGLVITAHHPTPSPSPCGLALSP-------------IPQPPAVGPPQPHLTFIHPKPVSLTGVRHKQPPKIVPAPKPEAVSLVLKSACIAPAAFTGQPQKVIMTSAPLKRE----------GILASTVSPSSVVIASAAITRASGVTEFLS-------------HSTSSQPSPASRLFSPSAVQDALVKGEQAALHGG-PQAPATGSSRDCPNSGQASPCPSEQSPSPQSPQNNCSGKSTDPKNVAALKNRQ-KHISAEQKRRFNIRMGFNTLNSLIS----NNSKQTSHAITLQKTMEYITKLQQERMQMQEEARRLREEIEELNTTIISCQQLLPATGVPVNCRQFDHMKDMFDEYVKSRILQNWKFWIFSMIIKPLFESFKGMVSTSSLEEFHRTALSWLDQHCSLPVLRPMVLSTLRQLSTTTSILTDP-SQLPEQASEAVTRIGKRSGES---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2VPU4-1", "uniprot_id": "MLXIP_MOUSE", "id": "Q2VPU4-1", "name": "MLX-interacting protein", "aln": "----------MAADVFMCSPRRPRSRGRSVLLKPQVPEDDDDSDTDEPSPPPPSGVATSARAHASAAPLPPRAG----PGREEPPRRQQIIHSGHFMVSSPHR------EHPPKKGYDFDTVNKQTCQTYSFG---------KTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRRNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSS---LAQDDDMLYWHKHGDGWKT---------PVPMEEDSLLDTDMLMSEFSDTLFSTLS----------------SHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMD------------------------------TFEPFQDLFSSSRSIFGS-----MLPPPSSLP-----AADPSSPPS----------QGNILPNTALPPASLPN-----------------------------SLITSSAAPSLDPTEGQGCERTSQTVDPFIQP------ADFGPSEPPLSVPQPFLPVFTMTLLSP---------------GPAPAPVPTALPLVPSPAPTLNPPTPPAFLQPQKFAGVSKSTPVITHTASATLT-----HDASATTFSQNQGLVITAHHPTPSSSPCALALSP-------------VPQPPAVGPPQPHLTFIHPKPVSLTGVRHKQPPKIVPAPKPEPVSLVLKNACIAPAAFSGQPQKVIMTSAPLKRE----------GILASTVSPSNVVIASAAITRASGVTEFLS-------------HSTSSQPSPVSRLFSPSTVQDSLVKGEQVSLHGGSPQVPATGSSRDCPNSGQASPCPSEQSPSPQSPQNNCSGKSTDPKNVAALKNRQ-KHISAEQKRRFNIRMGFNTLNSLIS----NNSKQTSHAITLQKTMEYITKLQQERMQMQEEARRLREEIEELNTTIISCQQLLPATGVPVNCRQLDHMRDMFDEYVKSRTLQNWKFWIFSMIIKPLFESFKGMVSTSSLEEFHRTALSWLDQHCSLPVLRPMVLSTLRQLSTTTSILTDP-SQLPEQASEAVTRMGKRSGES---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAP2-1", "uniprot_id": "MLXIP_HUMAN", "id": "Q9HAP2-1", "name": "MLX-interacting protein", "aln": "----------MAADVFMCSPRRPRSRGRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAG----PGREEPPRRQQIIHSGHFMVSSPHR------EHPPKKGYDFDTVNKQTCQTYSFG---------KTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSS---LVQDDDMLYWHKHGDGWKT---------PVPMEEDPLLDTDMLMSEFSDTLFSTLS----------------SHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMD------------------------------TFEPFQDLFSSSRSIFGS-----MLPASASAP-----VPDPNNPPA----------QESILPTTALPTVSLPD-----------------------------SLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP------TDFGPSEPPLSVPQPFLPVFTMPLLSP---------------SPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLT-----HDAPATTFSQSQGLVITTHHPAPSAAPCGLALSP-------------VTRP-----PQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKRE----------GMLASTVSQSNVVIAPAAIARAPGVPEFHSS-----ILVTDLGHGTSSPPAPVSRLF-PSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKS-DPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLIS----NNSKLTSHAITLQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQLSTSTSILTDP-AQLPEQASKAVTRIGKRLGES---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VID4-1", "uniprot_id": "Q9VID4_DROME", "id": "Q9VID4-1", "name": "", "aln": "MMLNKHEGYQRTSQMFPHQQHQLPQLHQQPYLQQSLCQNFQQLQYETGVGASASGSAEATADLLKAERESIHSGQFMVSHFEAEEAQDDLEDDGEVKMLDPEDPGLGKPGEPTNTCRDVQLYVPQTVAHFSAMDQEGDESSMSMVTSHLEIETSLTKLFKCMNLAYSQKLTSPKWNHFKGVRLRWKDKIRLNNVIWRCWHMQFIQKRRTPVCQFASPLD----VDIHSNPQTVVLEGKYWKRHSAVIKAEYRKWRRNYRSKATGCLTYDSKSELDFLEWSPLNDRNLMPDDWTTDTLFSAINVPFPFPDSREIARGAGIADFIQPSLGPLQPNLDDIDISFSDLIPTTRLPPVPEEGTDAEMLKNDEYCLSAIVGAPHTLYCNDSIMDVVNSSNNGAVNVDASMLELNTPINNVSYGEVEQRFSVARQVQQSNNDSQLLGDSGSMSGRIHGGKHFGPASANDNNTNRCVINGRVAKSTQRPFRREPHNYDKAQPTMHQTNLYQQMLAEQQKNQQQQHVVVSSFQASQQQQLAQQQPFSAQATNAFNNQSFISSYADNYQHQQQLNVKVEPLHADVLSLLNDNAYNSIGYKPYPQFKKSASTGTFLNVPRQTQQQQSYLQQEPPQMQQSLPVGMGNQQILQLTRQQQVNNTQQQQHQSTVASLLQQQHQQQNHQQQQLQTAVSSATWVSPNTILPKEIYRSNSLPLNVSLNKLPDGRQLHHEQPFAVPKYHSKSKSRVRSNSMHQQHTSVVSAAGAGSSSLGAHSCSNLLVTQQMQQATSDPMLNSTLAQLLTSNSRLQTAVANSSSSNSPSVSAIATTNSNSNAPPVHYANVTSPLSVPVPTHQHSPKKSASLPMAVNSALHSPPLGSKIHGIGLATANVGSNSLSLSPESTFHES-QDSPLSPTTSLKFQPRDTQRRAGHIHAEQKRRYNIKNGFDTLHALIPQLQLNPNAKLSKAAMLQKGADHIKQLRQERNVLKDKIEALRMERDELNNSLTHLHSILPANGAPVTRQGTEHVRQLYDIYVRYNTMNDWKFWILGLILEPLLASYTSTVSSASLDELRRTAFLWVDQHCSLIDLRPAVTNKLKYLSMHTDIVSEPPSTLQEEVAKALQNSSGQHPNLHGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::* . :: . :. *: .: :: :: : : ...** * .: .* . ::* . * :::: ..*.. : .*. .*.:. *.: ** :* . :.**.*::******:**.**** **.****::***::*:*:*******.***.*:**:::**:.***:*.:*** ** * .*:::. ****** : :: **:*** ::.: * .* : : . : : *.*.* *.*: :. : . :::* :. :..*. :: * . : : * * : ..:: .* * :: .:: ** :*.: * :* . * . . . ..: : : .. * *. ::... .* * :::: :.* : :* : *.* * . .:.**. .*.. :* . : ** : *. .. . :*: ... * :.: *: :.*.: :: :. ... :** :. : * :*.::. : *. :: . . : : *:. * ..::: .:. ::.: ::: . * :: * ...:* :: :.:..*. : : : **. . *.. .. . .* . : .**. * . .* *. * . * :*. :* *:. . : . * . .:*: ** ******:**: *: *::**. * . *:* *** ::*.:*:*** :::: . ** * :*** :: :.:***.*.**. : :*:::::* **: . :::*****:.:*::**: *:.. **::**:*::***: *:****** *** * ..*: ** *.*:::* : * *:.::*: . . : : ", "identical_positions": 223, "similar_positions": 345, "identity": "19.84%" }, { "cls_id": "homologset.agr.MGI:2141207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TPL3-1", "uniprot_id": "BACD3_RAT", "id": "Q7TPL3-1", "name": "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3", "aln": "MEEMSGESVVTSAVPAAATRTTSFKGASPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLLEECQAALQNKDTYEPFCKVPVITSSKEEQRLIATSDKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERERIERVRRIHIKRPDDRAHLHQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922M3-1", "uniprot_id": "BACD3_MOUSE", "id": "Q922M3-1", "name": "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3", "aln": "MEEMSGDSVVSSAVPAAATRTTSFKGASPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGGVPLPESRREIEELLAEAKYYLVQGLLEECQAALQNKDTYEPFCKVPVITSSKEEQRLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERERIERVRRIHIKRPDDRAHLHQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3F6-1", "uniprot_id": "BACD3_HUMAN", "id": "Q9H3F6-1", "name": "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3", "aln": "MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERER--IERVRRIHIKRPDDRAHLHQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:***:***************:*******************************************************************.*************************:*****************************:*****:**************************************************************************************************************************************** ********************", "identical_positions": 306, "similar_positions": 7, "identity": "97.14%" }, { "cls_id": "homologset.agr.MGI:2141255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PD29-1", "uniprot_id": "ZN513_MOUSE", "id": "Q6PD29-1", "name": "Zinc finger protein 513", "aln": "MPRRKQSHPQPVKCEGVKVDTEDSFDEG-PGALVLESDLLLGQDLEFEEEEEED-----EGDGHNDQLMGFERDSEGDSQGARPGLPYGLSDDESGGGRALSAESEVEEP----ARGPGEARGERPGPACQLCG------------GPTGEGPCCGAG----GPGGGPPLP----PRLLYSCRLCAFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHT--GP---PTPPCPTCGFRCCAPRPTRP---PSPTEQEGTMPRRSEDALILPDLSLHVPPGGASFLPDCGQLRGEGESLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRLGAAMCGRCMRGEAGGVATGGPQGPGDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAGGPGLSAPEGWAPPHSPPSVLSTRGPAALGATGSRALHSDSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FWU5-1", "uniprot_id": "ZN513_RAT", "id": "Q5FWU5-1", "name": "Zinc finger protein 513", "aln": "MPRRKQSHPQPVKCEGVKVDTEDSFDEG-PGALVLESDLLLGQDLEFEEEEEEE-----EGDGHNDQLMGFERDSEGDSQGARPGLPYGLSDDESGGGRALSAESEVEEP----ARGPGEARGERPGPACQLCG------------GPTGEGPCCGAG----GPGGGPPLP----PRLLYSCRLCAFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHT--GP---PTPPCPTCGFRCCAPRPTRP---PSPTEQEGTMPRRSEDALILPDLSLHVPPGGTSFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRLGTAMCGRCMRGESGGGGSGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAGGPGLSAPEGWAPPHSPPSVLSTRGSAALGATGSRALHTDSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8E2-1", "uniprot_id": "ZN513_HUMAN", "id": "Q8N8E2-1", "name": "Zinc finger protein 513", "aln": "MPRRKQSHPQPVKCEGVKVDTEDSLDEG-PGALVLESDLLLGQDLEFEEEEEEE-----EGDGNSDQLMGFERDSEGDSLGARPGLPYGLSDDESGGGRALSAESEVEEP----ARGPGEARGERPGPACQLCG------------GPTGEGPCCGAG----GPGGGPLLP----PRLLYSCRLCTFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHA--GP---PTPPCPTCGFRCCTPRPARP---PSPTEQEGAVPRRPEDALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRLGAAMCGRCMRGEAGGGASGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAGGPGLSASEGWAPPHSPPSVLSSRGPPALGTAGSRAVHTDSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GDS0-1", "uniprot_id": "R4GDS0_DANRE", "id": "R4GDS0-1", "name": "Zinc finger protein 513", "aln": "MPRRKQQNPQP-----VKLDSEDGVGTVRPTNLTFESDFLLGQELEFSDPDNDQKIIGLEKFSADISLPGFPLGDEENSPFSRLSMESDADDLRATESEREERVSESAFPSYLSCRGCGQLLEDPLGPGMDLVGPYCMRCCKGNVEGIVDRKLCSGLGLQAESRGGGNEGTGEDGSLKLHSCTLCGFTSRYTNHVKRHMKTHNGEKPYGCPLCSYASAQLVNLQRHLRIHTGEKPYKCNTCTFACSSLGNLKRHQRMHATIGPGQSVTQPVSGNGLNHSTAAQKEKEAVPAPTEVAGAVRSVTRPHMGRDGNYLQTFDGLRLAQQTSTGVLQSGQ--AASQPAALPPMFFPFTCRLCGMALDDEDGS--SAQICAKCTLEMLTKDTHGCPAERGDKVYTCAACPFLTHYPNHLARHMKTHSGEKPYKCPQCDYASAHFDNLKRHHRVHTGEKPYKCHLCDYACGNLANLKRHQRVHSGAKPFQCAICNYSCNQSMNLKRHMLRHTGEKPHKCQECGYTTGHWDNYKRHQKKHSLAGDG---------WVKVPLPGNEEEVEDDEEV-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.:*** **:*:**... * *.:***:****:***.: :::: * . . .* ** ..* :* :* .: . .* .: .. . ** * .** *: : **. :* * * ... *.* * . *** . . *:** ** *.*:*:.*:****:**.****: * *.********* ** * *******:* *.*********:**** *: ** * * . *:. .:. . *:*** *:: .. : . *:. * . : .*: ..: . .** ::**:*** ** *:: :** .: :*.:* * * .** ::*: *** *******************::*.:* *****:******:*********** ** ************ *:*** ***:*::***********************.:* *.************** *. .* * *. * . . .. : ", "identical_positions": 251, "similar_positions": 120, "identity": "43.35%" }, { "cls_id": "homologset.agr.MGI:2141291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41223-1", "uniprot_id": "BUD31_HUMAN", "id": "P41223-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGH1-1", "uniprot_id": "BUD31_MOUSE", "id": "Q6PGH1-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70454-1", "uniprot_id": "BUD31_RAT", "id": "O70454-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q567Z7-1", "uniprot_id": "BUD31_DANRE", "id": "Q567Z7-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KPPPDGWELVEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRLHHQRSRYIFDLFYKRKAISRELYKYCIRGGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKGKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97454-1", "uniprot_id": "O97454_DROME", "id": "O97454-1", "name": "Protein BUD31 homolog", "aln": "MPKVRRSR-KPPPDGWELIEPTLEELEQKMREAETEPHE--GKRITESLWPIFKIHHQKTRYIYDLFYRRKAISRELYDYCLKEKIADGNLIAKWKKSGYENLCCLRCIQTRDTNFGTNCICRVPKCKLEEGR--------IVECVHCGCRGCSG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25337-1", "uniprot_id": "BUD31_YEAST", "id": "P25337-1", "name": "Pre-mRNA-splicing factor BUD31", "aln": "MPRIKTRRSKPAPDGFEKIKPTLTDFEIQLRDAQKDKSSKLAAKSNEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLCCLRCIQKNETNNGSTCICRVPRAQLEEEARKKGTQVSFHQCVHCGCRGCASTD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::: * *..***:* ::*** ::: ::*:*:.: . . : *.** *:::***::***: *:*:*****::**.: :: ** *****:* ***:********..:** *:.******: :** : :*.*******:. ", "identical_positions": 70, "similar_positions": 49, "identity": "44.59%" }, { "cls_id": "homologset.agr.MGI:2141314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8K3-1", "uniprot_id": "NAA11_RAT", "id": "Q4V8K3-1", "name": "N-alpha-acetyltransferase 11", "aln": "--MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE---------DE---------------DG--------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFSAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLAQMADELRRQLVLKKSRYVVLGSEENQEAQDSTLPDAEEACQPENPAGKGSEACQPENPAGKGSEACQPENPAGKDTGSHSTDVQDSSEYLDSTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UX61-1", "uniprot_id": "NAA11_MOUSE", "id": "Q3UX61-1", "name": "N-alpha-acetyltransferase 11", "aln": "--MNIRNARPDDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE---------DE---------------DG--------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFGAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLSQMTDELRRQLVLKKNRYVVLGSEE---TQGGTLPDAGEACLPKNPTSKDS-----------GS--------------SDSTDVQDSSEDLDSIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSU3-1", "uniprot_id": "NAA11_HUMAN", "id": "Q9BSU3-1", "name": "N-alpha-acetyltransferase 11", "aln": "--MNIRNAQPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSYIAE---------DE---------------DG--------------KIVGYVLAKMEE--EPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRPALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLSQMADELRRQMDLKKGGYVVLGSRENQETQGSTLSDSEEACQQKNPATEES-----------GSDSKEPKES------VESTNVQDSSESSDSTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT75-1", "uniprot_id": "Q9VT75_DROME", "id": "Q9VT75-1", "name": "N-terminal amino-acid N(alpha)-acetyltransferase NatA", "aln": "--MNIRCAKPEDLMTMQHCNLLCLPENYQMKYYFYHGLTWPQLSYVAV---------DD---------------KG--------------AIVGYVLAKMEEP-EPNEESRHGHITSLAVKRSYRRLGLAQKLMNQASQAMVECFNAQYVSLHVRKSNRAALNLYTNALKFKIIEVEPKYYADGEDAYAMRRDLSEFADEDQAKAAKQS------GEEE-----EKAVHRSGGHGHSHNHSGHDG----------------------------HCC-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07347-1", "uniprot_id": "ARD1_YEAST", "id": "P07347-1", "name": "N-terminal acetyltransferase A complex catalytic subunit ARD1", "aln": "MPINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDSDEQDENDKLELTLDGTNDGRTIKLDPTYLAPGEKLVGYVLVKMNDDPDQQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVL-KLEELQISNFTHRR-----LKENE------EKLEDDLESDLLEDIIKQGV----------------------------NDIIV-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** * :*:: **:.** ***** ****:** *:**: *::* *: .* :*****.**:: : :: . :******:* *::**:*:*::** ** *: * . *:*******:***.**:** ::* *:: .:* .** ********:: * :: : : : ..* : .: . . ", "identical_positions": 82, "similar_positions": 56, "identity": "28.37%" }, { "cls_id": "homologset.agr.MGI:2141341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DUQ1-1", "uniprot_id": "PRA15_HUMAN", "id": "P0DUQ1-1", "name": "PRAME family member 15", "aln": "MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS--HMDVSRYVSPE--QKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60810-1", "uniprot_id": "PRAM4_HUMAN", "id": "O60810-1", "name": "PRAME family member 4", "aln": "MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMKGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS--HMDVSRYVSPE--QKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VT98-1", "uniprot_id": "PRA20_HUMAN", "id": "Q5VT98-1", "name": "PRAME family member 20", "aln": "--MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWPFLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPLQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS--DID-SRYISPE--QKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E0CZF1-1", "uniprot_id": "E0CZF1_MOUSE", "id": "E0CZF1-1", "name": "", "aln": "--MSGQTPP------THTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISS-HFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *** ::** .:** :*:****** :**.** ***: *: : ** ** :*** **: .*:* * *::**:***:* *. .: ** ******:::: . ** : ::* * :: ::: :: ** :* *.*:::* :.. ::: : :: *.*** . :::** *::: . : **.*:: .: : * *:*:* .*.* *:.*:.*:*:*:**:*:.*: . : * :. : : * :: :** ::.***:::*: * **..:::*:*.** *.*: *:**:*:: : *:. :* .: :** *:: * * .*:**::****** *** **:: * : ***:**:*****:* :*. :.* .* :. .**: *: ** .:: :* **** :.*. * :. .**.*: *** :* :*.*: * *.** * .**: ..** .* ", "identical_positions": 175, "similar_positions": 162, "identity": "36.16%" }, { "cls_id": "homologset.agr.MGI:2141353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A758-1", "uniprot_id": "D4A758_RAT", "id": "D4A758-1", "name": "", "aln": "MITLTELKCLADAQSSYHILKPWWDVFWYYLTLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDLLKASENTSSNSGLPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVSILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKTLLSTSGGSADIDASKQSLPYPQPGLESPGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQRDIIYRVYLKQIIVKVILFVLIITYVPYFLSYITLEIDCSIDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVMLYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNSQDKVELHLFMLNGLPDNVFELTDMEVLSLELIPEVKLPAAASQLVNLRELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSSMQPEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELLSCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKLWHNNIAYIPAQIGALSNLEQLYLGHNNIESLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLTNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGRNSLTDLSPLVGELSNLTHLELIGNYLETLPVELEGCQSLKRSCLIVEDSLLNSLPLPVTERLQTCLDKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DU41-1", "uniprot_id": "LRC8B_MOUSE", "id": "Q5DU41-1", "name": "Volume-regulated anion channel subunit LRRC8B", "aln": "MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNQCAVPWDLLKGSENASSNSGLLLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVSILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKTLLSTSGGSADIDASKQSLPYPQPGLESPGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQRDIIYRVYLKQIIVKVILFVLIITYVPYFLSYITLEIDCSIDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVMLYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVERLKSKLVKNSQDKVELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPAAVAQLVNLRELHVYHSSLVVDHPALAFLEENLRILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSSLHLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELLSCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKLWHNNIAYIPAQIGALSNLEQLFLGHNNIESLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLTNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGRNSLTDLSPLVGELSNLTHLELTGNYLETLPVELEGCQSLKRSCLIVEDSLLNSLPLPVAERLQTCLDKC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P9F7-1", "uniprot_id": "LRC8B_HUMAN", "id": "Q6P9F7-1", "name": "Volume-regulated anion channel subunit LRRC8B", "aln": "MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************:*********************************:******:**.* *:***.* *******************************************************************:********************************* ***:** *****:.*************.*****************************:****:*****************************::********:********************************:************************************************************************************:********:***:******************:***************:*.:*****:**:********************:*************************************::: *************************************************************:**********************:**************** .*************************** *.*****.*******************************:*******************************:*** :*** ************ ******** **********.*****:.***:*****:**********", "identical_positions": 748, "similar_positions": 43, "identity": "93.15%" }, { "cls_id": "homologset.agr.MGI:2141396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6J9G1-1", "uniprot_id": "STYK1_MOUSE", "id": "Q6J9G1-1", "name": "Tyrosine-protein kinase STYK1", "aln": "MGEKGHLSRVLLECSLSDKLCVVREKQYEVIIVPALLVGGFLILLAIILWLFIRGQRSQRQSPGP----------------------RGTASVPASRGRSQEAAGHGEKVLLPLKETSVEGFLRAATPRLAK-LQVPREQLLEVLEQIHSGSCGTLYHATMTTKDH---PKPKSVVLKALEDPVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTERLPLYMMLEDVVPGDLLSFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQILLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAHGAISSARSSTIPLKWLAPERLLLRPASIRGDIWSFGILLYEMVTLGAPPYPEVPPTSILQYLQRKKIMKRPSSCSHAMYNIMKCCWRWSEDSRPLLGQLLQRLEAASRSADDKAVLQVPELVVPELYADVAGIRAESISYSFSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHY0-1", "uniprot_id": "D3ZHY0_RAT", "id": "D3ZHY0-1", "name": "Tyrosine-protein kinase STYK1", "aln": "MGEKGRLSRLLLECSLSDKLCVVQEKQYEVIIVPALLVGSFLILLAIILWLFIRGQRSQRQHPGP----------------------RGTTSVPASRGRSQEAVGHGEKVFVPLKETSVESFLRAVTPSLAK-LQVPREQLLEVLEQIHSGSCGTLYHAKMTTMEH---PNPKSVVLKALEGSVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTERLPLYMMLEDVVPGDLLNFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQVLLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHTHGAISSARSSTIPLKWLAPERLLLRPASIRGDVWSFGILLYEMVTLGAPPYPEVPPTSILQYLQRKKIMKRPSSCTHAMYNIMKYCWRWSEDSRPLPGELRLRLEAASRTANDKAVLQVPELVVPDLYADVAGISTESLSDSYSVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6J9G0-1", "uniprot_id": "STYK1_HUMAN", "id": "Q6J9G0-1", "name": "Tyrosine-protein kinase STYK1", "aln": "MG----MTRMLLECSLSDKLCVIQEKQYEVIIVPTLLVTIFLILLGVILWLFIREQRTQQQRSGP----------------------QGIAPVPPPRDLSWEAG-HGGNVALPLKETSVENFLGATTPALAK-LQVPREQLSEVLEQICSGSCGPIFRANMNTGDP---SKPKSVILKALKEPAGLHEVQDFLGRIQFHQYLGKHKNLVQLEGCCTEKLPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGKQVLLALEFLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEVYTRGAISST--QTIPLKWLAPERLLLRPASIRADVWSFGILLYEMVTLGAPPYPEVPPTSILEHLQRRKIMKRPSSCTHTMYSIMKSCWRWREADRPSPRELRLRLEAAIKTADDEAVLQVPELVVPELYAAVAGIRVESLFYNYSML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q614-1", "uniprot_id": "F1Q614_DANRE", "id": "F1Q614-1", "name": "", "aln": "---MSNLTNTTFACIPG-SLCEVLFYQVELIVVPVLFLLLFLAIMIILLVLKCSHKKSYRHKHHRKENDHTQHHHN----------TQGSHRSNRRHLQGIDAPAELNPMEHEVIPMTAQAPHEVQSSASAIPQQTT-ERHPSSFQLLSPLPISFSVKQDN-FTLHRAAIDRQPVILRVLKESANARERQSFLGFSHFLSELGPHESLPKLLGVVSARTPLMMAVEELEHRDLLGFLWRCRQDHTGQA-APCDMTERRIFTMGAQIASALEYLHSKNCIHGNVKARSVLVGQDLSVKLWGLGPAYHRKSNASSIEDLEEIETRKWQAPELLARQPLQQSSDVWSFGILLYEMVTLGEAPFPNIMASELLQHLQRENTLKRPPNCSNTLYSIMKSCCKWRAKDRVSLAELIRKLQSGERSANDQAVLRVSEPLDIEKYMQEAGYGES---LNYAVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9QCV8-1", "uniprot_id": "E9QCV8_DANRE", "id": "E9QCV8-1", "name": "", "aln": "--MAASSSAASSECEAGDALCEIRVYEQEVIIVPVIFFMMFLITLLFIMLLRFCPEKVERLQPASSRVSRTRRNLQGIDAPLGLNALEGEPIALDTTTYMTFNPATPARLDHANNVAFTDGMFGATASAFAKPRELPRQRLPENFNGVAPLPASYSLKSDSPISLYRARMENRNVVLRVLKDSASNQESQSFLGFAAFLSQLGPHPFLPELLGVISLRAPLITVIEEMENRDLLGFLWRCRQDNVGPD-GMCQMTEKKIFNMASHVASALDFLHGKDLHHCNLKARNVLVSRICTAKLWGLDDLYVRTSGSGNYS--EDPGRKKWQAPELLAKRPSTPKSDIWSFGLLLYEMVTLGEVPFAEIPVKELLQHHQRVKPIRKPNNCSNSLYSIIKSCCHWKEQDRPSLAEVRRKLQSGEKSASDSSVLRVPEPINIQQYLKEAGYGES---NSYTVF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . ** : : *:*:**.::. ** : .:: * :: : .* : .: . :. * : . :: . :: : . . . : . : *:*:.*: ... :* *.*:* * . ** * * :* * : : ** :*:: ***.*** **:* ::**:::: :. :: **::*: *. * :: **.:*: : ** *. * : .. . . ** *** * :* .*:****:********* *:.:: ..:*:: ** : :::* .*::::*.*:* * :* .* :: :*::. ::*.*.:**:*.* : : * ** . .::::", "identical_positions": 95, "similar_positions": 130, "identity": "20.88%" }, { "cls_id": "homologset.agr.MGI:2141402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0ZCA7-1", "uniprot_id": "CLC2L_RAT", "id": "Q0ZCA7-1", "name": "C-type lectin domain family 2 member L", "aln": "MEPAREPPARARPPPP-AAR--PAPAAPRPRSPAEAEARGPEGLLRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCETPCPEDWLLYGRKCYYFSEEPRDWNTGRQYCHTHEAALAVIQSQKELEFMFKFTRREPWIGLRRVGDDFHWVNGDPFDPDTFTISGTGECVFVEPTRLVSTECLTTRPWVCSKMAYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C7M9-1", "uniprot_id": "CLC2L_MOUSE", "id": "P0C7M9-1", "name": "C-type lectin domain family 2 member L", "aln": "MEPAREPPARARPPPP-AAR--PAPAAPRPRSPAEAEARGPEGLLRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCETPCPEDWLLYGRKCYYFSEEPRDWNTGRQYCHTHEAALAVIQSQKELEFMFKFTRREPWIGLRRVGDDFHWVNGDPFDPDTFTISGMGECVFVEPTRLVSTECLTTRPWVCSKMAYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7M8-1", "uniprot_id": "CLC2L_HUMAN", "id": "P0C7M8-1", "name": "C-type lectin domain family 2 member L", "aln": "MEPAREPPSRARPPPPLAARPAPAPAAPRPRSPAEAEARGPEGLLRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCEAPCPEDWLLYGRKCYFFSEEPRDWNTGRQYCHTHEAVLAVIQSQKELEFMFKFTRREPWIGLRRVGDEFHWVNGDPFDPDTFTIAGPGECVFVEPTRLVSTECLMTRPWVCSKMAYT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:******* *** ***************************************************************************:**************:********************.******************************:****************:* ***************** ************", "identical_positions": 203, "similar_positions": 6, "identity": "94.86%" }, { "cls_id": "homologset.agr.MGI:2141413", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4V7-1", "uniprot_id": "D4A4V7_RAT", "id": "D4A4V7-1", "name": "", "aln": "MQFVSTRPQPQQLGIQGLGLDSGSWSWAQALPPEEVCHQEPALRAEMAEGMPPMQAQEWDMDARRPMPFQFPPFPDRAPVFPDRMMREPQLPTAEISLWTVVAAIQAVERKVDAQASQLLNLEGRTGTAEKKLADCEKTAVEFGNHMESKWAVLGTLLQEYGLLQRRLENLENLLRNRNFWVLRLPPGSKGEAPKVPVTFVDIAVYFSEDEWKNLDEWQKELYSNLVKENYKTLMSLDTDGPVSKPDAPVQAEPREEPCVWEQHHPEEREIPGTADTGTEPLVPAQDMSSQVKREEAMCVRSQRSLEERAIPTESITDSPISAQDLLSRIKQEEQQCVWDQQDLAERDIPTDPNSESLISAHDILSWIKQEEQPYPWGPRDSMEGELGLDSGPSDSLLLVKNPPPASAQP-----------QTQPHQQSLPALAVPENPGGPGSRSLLEDGFPALPGERSTGGEPQPGGEGSAGGGGGGGSGGGGGTGASSSTSAGAGAGSGCGSCCPGGLRRSLLAHGARSKPYSCLECGKTFGVRKSLIIHHRSHTKERPYECAECEKSFNCHSGLIRHQMTHRGERPYKCSECEKTYSRKEHLQNHQRLHTGERPFQCALCGKSFIRKQNLLKHQRIHTGERPYTCGECGKSFRYKESLKDHLRVHNG-PGLGAPRPLQVPPERD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PVC2-1", "uniprot_id": "E9PVC2_MOUSE", "id": "E9PVC2-1", "name": "", "aln": "MQFVSTRPQPQQLGIQGLGLDSGSWSWAQALPPEEVCHQEPALRAEMAEGMPPMQAQEWDMDARRPMPFQFPPFPDRAPVFPDRMMREPQLPTAEISLWTVVAAIQAVERKVDAQASQLLNLEGRTGTAEKKLADCEKTAVEFGNHMESKWAVLGTLLQEYGLLQRRLENLENLLRNRNFWVLRLPPGSKGEAPKVPVTFVDIAVYFSEDEWKNLDEWQKELYSNLVKENYKTLMSLDTDGPVSKPDPPVQAEPREEPCVWEQHHPEEREIPVTADTGTETLVPAQDISSQVKREEALCVRGQRGLEDRAIPTESITDSPISAQDLLSRIKQEEQQCVWDQQDLAERDIPTDPNSESLISAHDILSWIKQEEQPYPWGPRDSMEGELGLDSGPSDSLLLVKNPPPSSAQP-----------QTQPHQQSLPALAVPENPGGPGSRSLLEDGFPALPGERSTGGEAQPTGEGSAGGGGGGGSGGGGGTGAGSGNSTGAGAGSGCGSCCPGGLRRSLLAHGARSKPYSCLECGKTFGVRKSLIIHHRSHTKERPYECAECEKSFNCHSGLIRHQMTHRGERPYKCSECEKTYSRKEHLQNHQRLHTGERPFQCALCGKSFIRKQNLLKHQRIHTGERPYTCGECGKSFRYKESLKDHLRVHNG-PGLGAPRPLQVPPERD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDV7-1", "uniprot_id": "ZN282_HUMAN", "id": "Q9UDV7-1", "name": "Zinc finger protein 282", "aln": "MQFVSTRPQPQQLGIQGLGLDSGSWSWAQALPPEEVCHQEPALRGEMAEGMPPMQAQEWDMDARRPMPFQFPPFPDRAPVFPDRMMREPQLPTAEISLWTVVAAIQAVERKVDAQASQLLNLEGRTGTAEKKLADCEKTAVEFGNHMESKWAVLGTLLQEYGLLQRRLENLENLLRNRNFWVLRLPPGSKGEAPKVPVTFVDIAVYFSEDEWKNLDEWQKELYNNLVKENYKTLMSLDAEGSVPKPDAPVQAEPREEPCVWEQRHPEEREIPMDPEAGAEPLVPAQDASSQVKREDTLCVRGQRGLEERAIPTESITDSPISAQDLLSRIKQEEHQCVWDQQDLADRDIPTDPNSESLISAHDILSWIKQEEQPYPWGPRDSMDGELGLDSGPSDSLLMVKNPPPAPPQPQPQPQPPQPQLQSQPQPQSLPPIAVAENPGGPPSRGLLDDGFQVLPGERGSG-EAPPGGDRSTGGGGGDGGGGGGG------AEAGTGAGGGCGSCCPGGLRRSLLLHGARSKPYSCPECGKSFGVRKSLIIHHRSHTKERPYECAECEKSFNCHSGLIRHQMTHRGERPYKCSECEKTYSRKEHLQNHQRLHTGERPFQCALCGKSFIRKQNLLKHQRIHTGERPYTCGECGKSFRYKESLKDHLRVHSGGPGPGAPRQLPPPPERD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************************.**********************************************************************************************************************************************************************************.**************::*.*.***.***************:******** .::*:*.****** *******:::***.**.**:**************************:**********:*************************************:**************:******:..** *:**: ****.:**.****** **.**:*** .*****.:* *. * *: *:*****.*.***** .:*:***.*************** ********** ****:******************************************************************************************************************************.* ** **** * *****", "identical_positions": 596, "similar_positions": 47, "identity": "87.91%" }, { "cls_id": "homologset.agr.MGI:2141418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE22-1", "uniprot_id": "D3ZE22_RAT", "id": "D3ZE22-1", "name": "", "aln": "MQGLSAPLLLSAEQLGPGAAWYRQEGSSECSWLQRSQPPKHRTNFSSRCPWARNSEFRPSERLQWLGPASARPEVARSGNSQGDCSPLPARHLSSARERFVPGALDTVNPEPACSLVPPTLDEPLPDAPPPPGGEAQNGPPPLTPYRLQTEAAKVEGMGTLECTRDSLLLWRGFTKGTPHHMGRLRNAKIHVERAVKQKKIFMIHGRYPVIRCLLRQRGWVEKKMVHPPGTILPPPSKDLDSSMLGDSDATEDEDEEESEMFRESQLLDLDGFLEFDDLDGIHALMSRMVRNETPYLIWTTRRDVLDCRFLSKDQ-MINHYARAGSFTTKVGLCLNLRNLPWFDEA-DADSFFPRCYRLGAEDDKKAFIEDFWLTAARN-VLKLVVKLEGRSQSIPIQAREEEALEDTQPKKQEKKPVTVSSDFVDEALSACEEHLSNIAHKDIDKDPNAPLYLSPDDWSLFLQRYYQIVHQGAELRY-----LEVQVQRCEDILQQLRAVVPQIDMEGDRNIWIVKPGAKSRGRGITCMDHLDEMLKLVDCNPMLMKDGKWIVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQRHLEASCHRHPMLPPDNMWSSQRFQAHLQEVDAPKAWSTVIVPGMKAAVIHALQTSQDNVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDRRMDRSCDTGAFELIYKQPAVEVPQYVGIRLVVEGSTIKKPM-------AVGHRRTGVLCSSLPHLLTQQGSGESKGSGSPTHRSAFRKNARVESLGHTTAAEKPETTATTPVPGKGKKDPFHFPSLHIKAWLPSP-RVHRPQSRVHRLQHSQ---------LVGSKALSTTGKALMTLPTAKVPMSFPPHPDLELAPSMLKPRKVG----------FELSCTP-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4Q9E5-1", "uniprot_id": "TTLL3_MOUSE", "id": "A4Q9E5-1", "name": "Tubulin monoglycylase TTLL3", "aln": "MQGVSSALLLSAGQLGPGAAWYRQEGSSECSWLRRSQPSELRTNFSSRWPWPRNSESRRSERLQWPGPASAKPEVASCGDSRRDYSSLPARHLSSARESSMPGALGTVNPQPVRTLVPPTLDEPLPDALRPPD--------------------------------DSLLLWRGLTKG-PNHMGRLRNAKIHVERAVKQKKIFMIHGRYPVIRCLLRQRGWVEKKMVHPPGTALPAPQKDLDSSMLGDSDATEDEDEEENEMFRESQLLDLDGFLEFDDLDGIHALMSRMVRNETPYLIWTTRRDVLDCRFLSKDQ-MINHYARAGSFTTKVGLCLNLRNLPWFDEA-DADSFFPRCYRLGAEDDKKAFIEDFWLTAARN-VLKLVVKLEEKSQSISIQAREEEAPEDTQPKKQEKKLVTVSSDFVDEALSACQEHLSSIAHKDIDKDPNSPLYLSPDDWSQFLQRYYQIVHEGAELRY-----LEVQVQRCEDILQQLQNVVPQLDMEGDRNIWIVKPGAKSRGRGIMCMNRLDEMLKLVDCNPMLMKDGKWIVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQRHLEASCHRHPMLPPDNMWSSQRFQAHLQEVDAPKAWSSVIVPGMKAAVIHALQTSQDNVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDRRLDRSCDTGAFELIYKQPAVEVPQYVGIRLLVEGSTIKKPV-------PVGHRRTGVR-SSLPHLLTQQGSGESKDSGSPTHRSASRKNARAESLEHT---EKPEPAAVASVSGKGKKAPFHFPSLHSKAWLPSP-RVHRPQGRVLRLQHDQ---------LVGSKALSTTGKALMTLPTAKVLMSFPPHPDLKLAPSMLKPGKVG----------FELCCTTWRVVLSGGIGEEGHRQRAA--------PRPSSAPGKGLSSTEPCSKTET------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4R7-1", "uniprot_id": "TTLL3_HUMAN", "id": "Q9Y4R7-1", "name": "Tubulin monoglycylase TTLL3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRLRNAKIYVERAVKQKKIFTIQGCYPVIRCLLRRRGWVEKKMVHRSGPTLLPPQKDLDSSAMGDSDTTEDEDEDEDEEFQPSQLFDFDDLLKFDDLDGTHALM--------------------------------------------VGLCLNLRNLPWFDEV-DANSFFPRCYCLGAEDDKKAFIEDFWLTAARN-VLKLVVKSEWKS--YPIQAVEEEASGDKQPKKQEKNPVLVSPEFVDEALCACEEYLSNLAHMDIDKDLEAPLYLTPEGWSLFLQRYYQVVHEGAELRH-----LDTQVQRCEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDRMLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGFTIKKPM-------AMCHRRMGVR-PAVP-LLTQRGSGEAR---------------------------------------------HHFPSLHTKAQLPSP-HVLRHQGQVLRRQHSK---------LVGTKALSTTGKALRTLPTAKVFISLPPNLDFKVAPSILKPRKAPA-LLCLRGPQLEVPCCLCPLKSEQFLAPVGRSRPKANSRPDCDKPRAEACPMKRLSPLKPLPLVGTFQRRRGLGDMKLGKPLLRFPTALVLDPTPNKKKQVKYLGLDSIAVGGSRVDGARPCTPGSTARA--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1ECV4-1", "uniprot_id": "TTLL3_DANRE", "id": "Q1ECV4-1", "name": "Tubulin monoglycylase TTLL3", "aln": "----------------------------------------------------------MHQHIQVP---------PLEGKSRINYVNLPLING-----------------------------------------------------------------------------------------DKLRTAKTLVDKAIKEKKVFSVQGPYPVIRAGLRARGWVERRLPRPS---FSQPRRHDHETETTDEGDSSDEDDLGEEVERD------------DEAEDLYDLMSRLVRHETPYFYWTTRRDSVDCRSLRKEQ-MTNHYAKAGSFTTKVGLCMHLRNLQWFDAA-DPDTFFPRCYRLGAQDEKHAFIDDFRRTACTSLLLYVLEKYEGDSEGEKMGEVHNAKSHGLRKTRKQHSSQRIETSVIDSALHVCQEYLNSLEHCDIDNNLETNSTISEQQWKVFLQNYYLVVHEGINIEG-----CEYYLERCKCMLEQMRQVCPQMENDGICNIWIIKPGAKSRGRGIMCMNKLDDMLGLVDGDHCIMKDSKWVVQKYIERPLLVHDTKFDVRQWFLVTDWNPLTVWFYRECYLRFSTQPYSTHTLDSSVHLCNNSIQKHYQPSPDRSPSLPAECMWSCSQFRSWLAASGRAALWKAVVVPGMQKAVIQTLLTAQDSVEPRKASFELYGADFMLGRDLRPWLLEINASPTMAPSTGVTARLCPAVQEDTLRVVLDRRSERNTDTGGFQLIYKQAAVDVPQYVGVNLLIEGTSIRRPR-------APVHK---SLIQSHPEPLSKSTNHKSSLLSSPCTSGKENQSEEVKRACPN-LPNRKITMDQSLIFHPKRKRPHRLVLPSTCCVLPNPTELHHPQRLSHTQPQSD---------RPHTHRTRSNLPTLYRPTPSVEVINIRPRQALTSSHYIHKIHTVN------------LSYPVLRMQQNHRRSKNTFAEREG--------PKSS------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM91-1", "uniprot_id": "TTL3A_DROME", "id": "Q9VM91-1", "name": "Tubulin glycylase 3A", "aln": "MQTRPSSEPHRSRDQVTDGDRNRDQPQKCASATLAKKPVTPPAAPPPTPSNRVVAPLTVPVIQLTPAQSDSPVKLARPATPKETAISVPDHSNKENQPARTPPPSKSCPLGAPTN---------------------------------------------------------YVARRTWITTERMNELRRKAQEAAKQNKIFTIRGCFNSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERN--------------------IMSRFLEHMPVDFLWTNRKEKCDYIDQAKNPGMTINKFHRAPFTSKEGLCSQLRDFHWFFEEGTAEMYFPRCYNVWSPEELGEFIENFKLTACVAFLRAMLCKYHKQGSDAVFSCSG-----------------KIPYSAIDFAYKRLVEYIDSCQHNDIDFE--DPPKIWEHDWDAFLFQHQQLVNEDGRIQHDGGQRLEPMVKSCLSLVDKMKVHWPQYSLDGYQNMWIVKPANKCRGRGIILMDNLKKILGVVN--LSIASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQPLVVWFYRESYLRFSSQEYSLSNHHESVHLTNYAIQKKYTNG-KRDKRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGCMLASQENMDRRPNTFELFGADFMICENFYPWLIEINSSPDLGATTSVTARMCPQCLEDVVKVVIDRRTDPKAELGNFELAYRQVVPPTPAYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIHRAMPTFNATEYMEKYMVEPLSSSRSSLCSQLPQKSPSAAPALTATPSGATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQVQSTALPPKRQRSCGPRLSSTNPVESTEKKFKILIKNYSSNGNENMQDARPEVANSATATAISERKWRSLRNIAATAGGSSNLAARSKGPPLIAPPSLPTRRLTRTKSEIDSTGMHAIGRTFGRKSNGPRLPISISVQALHRGEPIVAALKQATSELQLSQAQMMSPRTALANKLNGSTLMVPASALPVG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : .:.* *::*:* ::* : :* * *****: : . . . . : .: : :* *** :**:: ** .: :***** : : :: **::* **. : :: * . . : : . :* * *::.. * *** : : . *. ** .: :*::. .:. : :: * :::::: ** . :* *:**:**. *.***** *:.*..:* :*: : ...:::*********::. ****:*****:*: :**.*****:.*:***:* :* . ..**** * :**:: . .* **.: **.. *:: * . * :.***: *:: : ::*:.:: * :***:****:: .:: ***:***:** :..:*.****:*. *.::**:** : . : * *:* *:* . .* *:*:.*.::* : : :: . : : . ... : : . : : . . . . * : : ", "identical_positions": 151, "similar_positions": 188, "identity": "13.84%" }, { "cls_id": "homologset.agr.MGI:2141439", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJN7-1", "uniprot_id": "GAR1A_RAT", "id": "Q5RJN7-1", "name": "Golgi-associated RAB2 interactor protein 1A", "aln": "MSKIRGLPPAIRDPGPGVELGVENGLLCQLIHSPEFNLFSDSVVFESTFIQ---------VTKQGNWMDAYERSATIILGVTSSVPSLPLPNILLMANVTWPQGPFSTCSTLG-APVITLSRILPLKYVELQIYDRTQRILRVRTVTEKIYYLRLHEKHPQAVFRFWIRLVKILQKGLSITTKDPRIHFTHCLVPKMPNSSTETTPESSRPASSQSSETIMLLAAERAGSSVLDLSNRHRFSEDRYTD--TKTDNSSNCKTASPVAS--LIGMPMRATLIHSLWEQEDSCETLLQAPVASSLGDNFLGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXB0-1", "uniprot_id": "GAR1A_MOUSE", "id": "B2RXB0-1", "name": "Golgi-associated RAB2 interactor protein 1A", "aln": "MSKIRGLPPAIRDPGPGVELGVVDGLLCQLIHSPEFNLFSDSVVFESTFIQ---------VTKQGNWMDAYERSATMILGVTSSVPSLPLPNILLMANVTWPHGPFSTCSTLG-APVITLSRILPLKYVELQIYDRTQRILRVRTVTEKIYYLRLHEKHPQAVFQFWIRLVKILQKGLSITTKDPRIQFTHCLVPKMSNSSTETATESSLPASSQNSEAIMLLAAERNSSSLLELSNRHQTSRDRHTDTATETDNSGNCKSTPLVAS--SASMPMRAALTHSLWEQEDSNENFLQAPVASSLGENLLGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXP2-1", "uniprot_id": "GAR1A_HUMAN", "id": "Q6NXP2-1", "name": "Golgi-associated RAB2 interactor protein 1A", "aln": "MSKIRGLPPEVREPGPGVELGVENGLLCQLIHSPEFNLFSNSVVFESNFIQTHVPEADFQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNVLLMANVTWPQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQRILRVRTVTEKIYYLKLHEKHPEIVFQFWVRLVKILQKGLSITTKDPRIKFTHCLVPKMPTNSTETTPENSLLSSPQPSEPLVLLAAEQTSGSFSQLSGKPQLTADRNNDTAIEIDNCSSYKIPSPVASPINLNIPMRAALSHSLWEQEDWNEHLLQVHIASYLGEHFLGA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********* :*:********* :****************:******.*** *** *** *. * ***:***************:*********:***:* ** * ****.***:********:**** ****************:******: **:**:*******************:*********...****:.*.* :*.* **.::*****: ..*. :**.: : : ** .* : **... * .. *** .:****:* ******** * :**. :** **:::**.", "identical_positions": 208, "similar_positions": 55, "identity": "67.31%" }, { "cls_id": "homologset.agr.MGI:2141440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14AI6-1", "uniprot_id": "RUSD3_MOUSE", "id": "Q14AI6-1", "name": "Mitochondrial mRNA pseudouridine synthase Rpusd3", "aln": "--------MGALRVLRYVSMIWRPELGSCARQRDAGFGTEARRPSQPHRSSKHKDLVEDQPFPGLLRTENLGLEELAHVLRAAVVDQKGPLVTLNKPQGLPVTGRPGELTLLSVLPQLSQALGLEHQELQVVRAPGKEASGLVLLSSCPQTASRLQKFFIHSRRAQRPTATYCAVTDGIPEPSEGTVCMPLKMEQMNDVDLAVPVMSPSRKDIQEGVKRTLSRFHVMATGRGCALVQLQPLTVFPNQLQVHMALQLCPILGDHTYAARVGTVLGQRFLWPAETTKPQRQVLDEALLRHLRLSPSQVAQMPLHLHLHRLLLPGTGSRDPPSELLAPLPPYFSRTLQCLRLSQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6T2-1", "uniprot_id": "D4A6T2_RAT", "id": "D4A6T2-1", "name": "", "aln": "--------MEALRALRSVSVVWRPGLGSSARRRDAGFGTEAR---------KRKDLVEDQPFPGLLRAENLGLEELAQVLRAAVVDQKG---------------RPGELTLLSVLPWLSQALGLEHQELQVVRAPGKEASGLVLLSSCPQTTSHLQKFFTHSRRAQRPTATYCAITDGVPEPSEGTVHIALRLERMDGIDLAVPVTSPSRKDIQEGVKRTLSHFHVTATGCGCALVQLQPLTVFPSQLQVHMALQLCPILGDHTYAARVGSVLGQRFLWPAETTKPQRQVLDEALLRYLHLSPSQVAQMPLHLHLHRLLLPGTRPRDPPSELLAPLPPYFSRTLQCLRLSQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P087-1", "uniprot_id": "RUSD3_HUMAN", "id": "Q6P087-1", "name": "Mitochondrial mRNA pseudouridine synthase RPUSD3", "aln": "MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQPFAGLLP-KNLSREELVDALRAAVVDRKGPLVTLNKPQGLPVTGKPGELTLFSVLPELSQSLGLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPAASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPLTVFSSQLQVHMVLQLCPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLHRLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . *.* . ** ** . .********* ::.. : ****.*** :**. ***...*******:** :******:**** ***:***..********.***:************:*:***:* *:************:***:* .***.: .*::*:::.::*:*** :****** ****:***:*:* *** *************..******.*****:**** *:****:******* ***..************* *:*:***.**:************** .**.* ***************** * *", "identical_positions": 224, "similar_positions": 61, "identity": "63.64%" }, { "cls_id": "homologset.agr.MGI:2141450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZQ5-1", "uniprot_id": "JAZF1_MOUSE", "id": "Q80ZQ5-1", "name": "Juxtaposed with another zinc finger protein 1", "aln": "-------------------------------------------------------------MTGIAAASFFSNTCRFGGCGLHFPTLADLIEHIEDNHIDTDPRVLEKQE---------LQQPTYVALSYINR----FMTDAARREQESLKKKIQPKLSLTLSSSVSRGNVSTPPRHSSGSLTPPVT-----------------------PPITP-----SSSFRSSTPTGSEYDEEEVDYEES-DSDESWTTESAISSEAILSSMCMNGG-------EEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVRKPFKCRCGKSYKTAQGLRHHTINFH--------------------------------------PP---------------VSAEMIRKMQQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZA80-1", "uniprot_id": "D3ZA80_RAT", "id": "D3ZA80-1", "name": "Juxtaposed with another zinc finger protein 1", "aln": "-------------------------------------------------------------MTGIAAASFFSNTCRFGGCGLHFPTLADLIEHIEDNHIDTDPRVLEKQE---------LQQPTYVALSYINR----FMTDAARREQESLKKKIQPKLSLTLSSSVSRGNVSTPPRHSSGSLTPPVT-----------------------PPITP-----SSSFRSSTPTGSEYDEEEVDYEES-DSDESWTTESAISSEAILSSMCMNGG-------EEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVRKPFKCRCGKSYKTAQGLRHHTINFH--------------------------------------PP---------------VSAEMIRKMQQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VZ6-1", "uniprot_id": "JAZF1_HUMAN", "id": "Q86VZ6-1", "name": "Juxtaposed with another zinc finger protein 1", "aln": "-------------------------------------------------------------MTGIAAASFFSNTCRFGGCGLHFPTLADLIEHIEDNHIDTDPRVLEKQE---------LQQPTYVALSYINR----FMTDAARREQESLKKKIQPKLSLTLSSSVSRGNVSTPPRHSSGSLTPPVT-----------------------PPITP-----SSSFRSSTPTGSEYDEEEVDYEES-DSDESWTTESAISSEAILSSMCMNGG-------EEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVRKPFKCRCGKSYKTAQGLRHHTINFH--------------------------------------PP---------------VSAEIIRKMQQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IVX5-1", "uniprot_id": "A0A0R4IVX5_DANRE", "id": "A0A0R4IVX5-1", "name": "Juxtaposed with another zinc finger protein 1", "aln": "--MPLCPHPPPIGCQPSKQLQLQSPPPLLLQRAAGYLITPIPHSLCLHWSANARTSANTSIMTGVAAASFFSNVCRFGGCGLHFESLGELIVHIEDNHIDTDPRVLERQE---------LQQPTYVALSYINR----FMTEAARREQETQKKKVQPKIAISVTGGVSRNSTATPPRHSNGSLTPPVT-----------------------PPITP-----SSSFRSSTPTGSECDEEEVEYEDS-DSDESWTTESAISSESILSSMCMNGG-------DEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVRKPFKCRCGKSYKTSQGLRHHTINFH--------------------------------------PP---------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9Z6-1", "uniprot_id": "Q9V9Z6_DROME", "id": "Q9V9Z6-1", "name": "C2H2-type domain-containing protein", "aln": "------------------------------------------------------------------MAVFLINVCKYNGCGITFPSLSDLISHIEDTHIDYDPKVVEQKE---------QAQPACLPLSYVLR----FITEENRKEAGS-------FLASNTTAPPTTNSGSNAAGHGNGNVELKRK-----------------------LAIKHHSYSMSSSNRSTTPTGSEMDEDEMVVTESEDSNDSWTTEEFSSEFIMRYGSRHSGGGSNGTPGNEKPFACPVPGCKKRYKNVNGIKYHSKNGHKKDGRVRKGYKCHCGKSYKTAQGLKNHALHTHNSQPDSVLNAQLANALAIGDGASAATPVGSSNTSSNPNPPPIIQRSNSPSQSLGSLSPSSISNMSSSASSCHGGSGSLSNGNNGNNGSTTSNTAILTSNGNVLQQLSAGNVVTLTNLPTQQHQQQQPQPQQQQQQQLHQNTATGNSNNNNLMRSTLGLVSIKTNNTPTAKSVSN---LMAANATASKILKLATNVANGGSSMDIVQQQQQHNKTTTTGQTVLNGSKPLPNLVNLGILTPATSPTKNTQTLTFTTTNGSTQQQQALVASLSKKTNILLLQEPTQLVQQVQQQQQQQQQQQQQLQQQVQQQHHVLPISPTSSVSGNSSKSSSPTPQQQQQQLLKKGKLELIEPMETDEGQSDGISESVAAAIASITDCKEDIGGATVAGIEVVGAGAVNEET", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32432-1", "uniprot_id": "SFP1_YEAST", "id": "P32432-1", "name": "Transcription factor SFP1", "aln": "MDFTTMTMASNMATSTTTTATSAHASINSSSNFNIDIDSNQNTPSILINNNSDSSNGKNTDFNGVNNIHQKNIMNNTNNVHLYSPNIMDQTLLTPQDIAKLRRESIAHSQGMGGVSWGSISVGSWLRDEIISRRNSIVPASANGAASAAASATTTATNTLQIQQPTKRPSVSNPPYHRGYSISPQIAYTAYLPNLEKQYCKDYSCCGLSLPGLHDLLRHYEEAHISTSPNTTNMSQIPMNSAGNTSSSVRMTNNTSSANYNLQNNMAANTKN----AGHKTNTMQAHSSNATNNTSINNMHANLQSNMDSNSTIRQSQHPHHQQNIIQQQLQSNSVNHTSG-----------------------------------------------------AVPTPSVMGSATASSTTANPNVISITGAPNSGLSMANHSQQLHLNGNLVDAVSTNDVFLRTSNSPSRHVPHNKQINSNNNSGININNNTSHNSNINMGSKNAMVNRPHTFNNYSLNKTSRNPIQHQSRKIDPHQTDLSPLVLVQDIDLSFMDDDILGPSNHNSMNSVVNPTTGSHNYNTFHSSVHAKSSQNMVEDQDIDDIDDDDDVDDDDDDDDDDDTENGSSSNGKSVHNNNYKMPQQAYIDDPARRLYVMDHEEQKPFKCPVIGCEKTYKNQNGLKYHRLHGHQNQKLHENPDGTFSVIDPDSTDSFGDGMGSAKDKPYRCEVCGKRYKNLNGLKYHRGHSTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. : .: : : . . : :.: : : . : * . :. : : . . :... * . .: : ..: *::*. :: .: : . .*. *.: :. : . . .:. . .. .. ..:*.:: : :.. .: :*: : : :. * : . : : ", "identical_positions": 9, "similar_positions": 84, "identity": "1.22%" }, { "cls_id": "homologset.agr.MGI:2141466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1RMZ1-1", "uniprot_id": "SAMTR_HUMAN", "id": "Q1RMZ1-1", "name": "S-adenosylmethionine sensor upstream of mTORC1", "aln": "MEPGAGGRNTARAQRAGSPNTPPPREQERKLEQEKLSGVVKSVHRRLRKKYREVGDFDKIWREHCE-DEETLCEYAVAMKNLADN-HWAKT---CEGEGRIEWCCSVCREYFQNGGKRKALEKDEKRAVLATKTTPALNMHESSQLEGHLTNLSFTNPEFITELLQASGKIRLLDVGSCFNPFLKFEEFLTVGIDIVPAVESVYKCDFLNLQLQQPLQLAQDAIDAFLKQLKNPIDSLPGELFHVVVFSLLLSYFPSPYQRWICCKKAHELLVLNGLLLIITPDSSHQNRHAMMMKSWKIAIESLGFKRFKYSKFSHMHLMAFRKISLKTTSDLVSRNYPGMLYIPQDFNSIEDEEYSNPSCYVRSDIEDEQLAYGFTELPDAPYDSDSGESQASSIPFYELEDPILLLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BXK4-1", "uniprot_id": "SAMTR_MOUSE", "id": "Q8BXK4-1", "name": "S-adenosylmethionine sensor upstream of mTORC1", "aln": "MEPGPGGRGAARGQRP--PNAAQPREQERKLEQEKLSGVVKSVHRRLRKKYREVGDFDKIWREHCE-DAETLCEYAVAMKNLADN-HWAKT---CEGEGRIEWCCSVCREYFQNGGKRKALEKDEKRAVLATKTTPALNVHESSKLEGPLTNLSFTSPDFITELLQASGKIRLLDVGSCFNPFLKFEEFLTVGIDIVPAVESVYKCDFLNLQLQQPLQLAQDAIDAFLKQLRNPIDALPGELFHVVVFSLLLSYFPSPYQRWICCKKAHELLVLNGLLLIITPDSSHQNRHAMMMKSWKIAIESLGFKRFKYSKFSHMHLMAFRKTSLKTTSDLVSRNYPGMLYIPQDFNSVEEEEYSNTSCYVRSDLEDEQLAYGFTELPEAPYDSDSGESQASSIPFYELEDPILLLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZV22-1", "uniprot_id": "D3ZV22_RAT", "id": "D3ZV22-1", "name": "S-adenosylmethionine sensor upstream of mTORC1", "aln": "EDTAPEALAVAPRPPPAAASAAASSFPTSSVRGETAG---PEGRRQRRQRYGAGAGWPRRSARTAA-PERRAAPGAGAEAGAGEAVRGGEE---RPPAAPQEIPRSVCREYFQNGGKRKALEKDEKRAVLATKTTPALNVHESSKLEGPLTNLSFTSPEFITELLQASGKIRLLDVGSCFNPFLKFEEFLTVGIDIVPAVESVYKCDFLNLQLQQPLQLAQDAIDAFLKQLKNPIDSLPGELFHVVVFSLLLSYFPSPYQRWICCKKAHELLVLNGLLLIITPDSSHQNRHAMMMKSWKIAIESLGFKRFKYSKFSHMHLMAFRKTSLKTTSDLVSRNYPGMLYIPQDFNSVEDEEYSNPSCYVRSDIEDEQLAYGFTELPDAPYDSDSGESQASSIPFYELEDPILLLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0P410-1", "uniprot_id": "SAMTR_DANRE", "id": "Q0P410-1", "name": "S-adenosylmethionine sensor upstream of mTORC1", "aln": "MDLRS-SAETDPDLSENHPGSVPAELQSRKQEQEKLSGVVKSVHRKLRRKYIEVGDFDKIWREHCE-DEQTLSEYAMAMKNLADN-HWANK---CEGEGRIEWCRSVCQEYFQDGGMRRVLEKDEKSARHATAGNANTDTNAPPQLSSISTSSTFQ-----------LGKIRLLDVGSCFNPFLKFDEFLTVGIDIVPAVESVYKCDFLNLQLQQPLQLASDALDAFLRQLRGPIDALPAELFHVVVFSLLLSYFPSPYQRWLCCKKAHELLTLNGLLLIITPDSSHQGRHALMMRSWRVAVESLGFKRYKYVKFSHMHLIAFRKVSPTTSSDLVSRNYPEMLYIPQDFNTFDEDGFADCYEPPRSDFEDDQMACSFAELPETPYDSDSGESQSSSAPFYELEDPILLQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W138-1", "uniprot_id": "SAMTR_DROME", "id": "Q9W138-1", "name": "Probable S-adenosyl-L-methionine-dependent methyltransferase", "aln": "---------------------------MATEEHQRLASIVKSCHESLRQLTKEYGATAAWQEHTSPRNAKQLAEYAKAMKQLAAIWETNDGKVELQARSRIKWAIDYITKYFFTEGIYLQKRQREQRLLESYRAEGKLGEVQCRLMEEPPD------------------RLHVLDVGSCFNPFSSAPHLEVTALDLCPATEDVLQADFLKVEVVPGIREPE--------LEEGSVRRLPASHYECVIFSLLLEYMPSAEQRLQCCLQAYDLLLPEGILVLITPDSQHVGKNAHLMKNWRYSLARIGLLRVRFEKLPHISCMVFRKAISRELS--------------QHWASIHREE-------------------GMCEEIRIPQDDS----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . :. *: . . . . . * * . . . . : . :** * .: *: : . :. ::::********** . .: ...:*: **.*.* :.***:::: :: .. ...: **.. :. *:*****.*:**. ** ** :*::** :*:*::*****.* .::* :*:.*: :: :*: * :: *:.*: :.*** * *.: :.. : .: * * *.. ", "identical_positions": 66, "similar_positions": 99, "identity": "16.1%" }, { "cls_id": "homologset.agr.MGI:2141485", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPP7-1", "uniprot_id": "D3ZPP7_RAT", "id": "D3ZPP7-1", "name": "", "aln": "-----------------------MLAPG-------GGPEQRSKLVLQWRQLSWITCWIALCAVEVLPACPFSCTCDSRSLEVDCSGLGLTTVP---PDVPAATQSLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDQLPRSVFQDLVNLTELQLRNNSIRTLDRDLLQHSPRLRHLDLSINGLAQLPQGLFDGLLALRSLSLRSNRLQSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRAVPMEMFNYCSQLEDEN-SAGLDAPG--PPCTKASPEPPKPKPGAEPEPEPSTACPQKQRYRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKR-----QPLMGDPEGEHE-DQKQISSVA--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGX3-1", "uniprot_id": "LRTM2_MOUSE", "id": "Q8BGX3-1", "name": "Leucine-rich repeat and transmembrane domain-containing protein 2", "aln": "-----------------------MLAPG-------GGPEQRSKLVLQWRQVSWITCWIALCAVEVIPACPFSCTCDSRSLEVDCSGLGLTTVP---PDVPAATQSLLLLNNKLSALPSWAFANLSNLQRLDLSNNFLDQLPRSIFEDLVNLTELQLRNNSIRTLDRDLLQHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRAVPMEMFNYCSQLEDENNSAGLDAPG--PPCTKASPEPPKPKPGAEPEPEPSTACPQKQRYRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKR-----QPLMGDPEGEHE-DQKQISSVA--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N967-1", "uniprot_id": "LRTM2_HUMAN", "id": "Q8N967-1", "name": "Leucine-rich repeat and transmembrane domain-containing protein 2", "aln": "-----------------------MLAPG-------SSPGQRGRLALQWRQVSWITCWIALYAVEALPTCPFSCKCDSRSLEVDCSGLGLTTVP---PDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYCSQLEDENSSAGLDIPG--PPCTKASPEPAKPKPGAEPEPEPSTACPQKQRHRPASVRRAMGTVIIAGVVCGVVCIMMVVAAAYGCIYASLMAKYHRELKKR-----QPLMGDPEGEHE-DQKQISSVA--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q6C3-1", "uniprot_id": "A0A8M9Q6C3_DANRE", "id": "A0A8M9Q6C3-1", "name": "", "aln": "----------------------MQLCTA-------PTVGRRRRGNPDSQGFLGVLS-VCATLLQLCAGCPSECVCN--SLEANCSGRSLVSVPA-LTSLPEGTHTLLLANNRLSSLPLSAFANLSTLETLDLSNNYLDNLPSRLFRELSNLSELSLRNNSLTVLDRELFRGLTHLRKLDLSLNGLAAVPLGLLDELQQLTWLSLAGNRLHALERATFEPLVNLQHLELGMNPWECDCNLRDFKHWMEWLIYRGGYVDAVECTLPKDLRGRDIRGVPVEMFNYCLQLEDENGGGTGSTKGGSPPCFRGTAAPSSDSAVVRTEAELPDCV--KQRYRPVSVRRAIGTVVIAGVVCGIVCIMMVAAAAYGCIYASLMAKYQRELKKR-----QPLMGDAEAETDPEEKQISSVA--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B753-1", "uniprot_id": "A0ACD6B753_DANRE", "id": "A0ACD6B753-1", "name": "", "aln": "MNILISSGLMTLVSLCGTSKSCPLLCSCNINQTDCSHLYQLASLDSILEQLPFDTTNLNLSKNNFTTVEPGSFSNLSALLQLDYSRNLLSAINPGCFSNLSGLLHLDLSRNLLSRVFPSSFSHLNSLEFLDLSVNLLVRLPVNLFSDLSSLNELVLRDNRLKELNPAQFKGLTELRRLDLSLNSLSHVPTHLLDGLQNLLWLSLVGNKLKTLDRSSLESANTLQQLLLEGNPWNCNCKLIPLKYWLEWIVYTGGRVDSPNCSFPTDLQGKDLASLPMELFRHCYPLQLQT------------------RKPSAPEAHQGPSGD-----CMRQRYRAVSVRRATATVVVAGVVCSVVCVLMVVTATYGCIYATLVAHQQQQMLQRKRQQQEPLMVEKEPAHDEKEDLMPTIGKGAEAMECVGWMAFPPEVCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. : . . : : . * . *: : * * :: . . * * .* ** : :*::*..*: **** * * .** :* :* .*.** **:* : *: :: . **:****:*.*: :* *:* * * *** .*:*: *:* ::*. .** * : ***:*:*:* :*:*:**: * ** :* *::*.:*:*:*: :*:*:*.:* *: :. *. .. .. : :**:*..***** .**::*****.:**::**.:*:******:*:*: :::: :* :*** : * : .:. :.::. ", "identical_positions": 112, "similar_positions": 111, "identity": "25.99%" }, { "cls_id": "homologset.agr.MGI:2141503", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JX31-1", "uniprot_id": "A0A0G2JX31_RAT", "id": "A0A0G2JX31-1", "name": "Protection of telomeres protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSLVP-----VTPYTYTPLNLLKEGAVANVYGVVKFFKPPYLSKGTDYCSVVTIVDPTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINSSGFASLTFEGTLGTPVTARTSSKVFSFTSQDQKMVEALRVWASKHIAASSSLVQLCDAQPLQYYDLTCQLLGKAEVDGTAFLLKVWDGTRTMFPSWRVSIQNLTFEGDLSHIQRLQSLVIDILVYDNHVQVAKSLKIGSFIRIYSLHTKLQSVDSETSKS-LLRLEFHLHGGTSYGRGIRVLPDESSCVDQLKKDLEC-ADSAVTQPSNGICQSKNEDSFVLSSSASGSVSLYEEERCQQVSSTILTDHQHLEKTPLCAVLKQKAPQQYRVRAKLRSYLPRRLPQSVKLICPQCHSLQEVPHEDSLDKLLQDAATKAPDIRLQGTSLYESKIWTTEGQGGRQVAVHFVKKDGVLPLSSECLILIEGGRLCEVSKLSSKFHSVIPVRSGPEDLELLDISAPFLIQGKLHHYGCKQCSSLKPIQNLNSLLNKGPWIPSSVAKVLGIVPLQYVFVMTFTLDDGTGVLDTYLKD-SENFFKIPASEVLTDDNLQRNLEAIMDMICPPGIKVDAYPWLECLIKSYNVTIGTEQRICYQIFDTTVAEDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WC1-1", "uniprot_id": "POTE1_MOUSE", "id": "Q91WC1-1", "name": "Protection of telomeres protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSLVS-----TAPYTYTPLNLLKEGTIANVYGVVKFFKPPYVSKGTDYCSVVTIVDQTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINCSGFASLTFEGTVGMPVTARTSSKVFSFTPQDQKMVEALRVWASKHISASSTLVQLCDAQPMQYYDLTCQLLGKAQVDSTAFLLKVWDGTQTVLPSWRVSTQDLTFEGDLSHIERLQSLVVDILVYDNHVQVARSIEVGCFLRLYSLHTKLQPGNSETSSSESLRLEFHLHGGTSYGRGIRVLPDTSPCVDQLKKALEG-ANLPVTETSTGICQSENGDSSALSNSGSGAVSPYEEERCQQVSATILTNHQHLEKTPLCAILTQKAPQQYRVRAKLRSYLPRRLSQSVKLLCPKCHSVQEVPHGDSLDKILQDAATEAPDIKLKATSLYYSKVWTTEDQGGRQVAVHFVKNNGILPASSECLILIEGGRLCEVSKLSSKFHSVMPVRSGPESLELLTLSAPFLIQGKVHHYGCKQCSSLKPIQNLNSRFHKGPWTPSSVAEALGVVPLQYVFVMVFTLDDGTGVLEAYLKD-SEHFFKIPASEVLTDDDLQRSLETIMDMICPPGIKVDAYPWLECLLKSYNVTIGTERRICYQIFDTTVAENVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUX5-1", "uniprot_id": "POTE1_HUMAN", "id": "Q9NUX5-1", "name": "Protection of telomeres protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSLVP-----ATNYIYTPLNQLKGGTIVNVYGVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCLLFSGNYEALPIIYKNGDIVRFHRLKIQVYKKETQGITSSGFASLTFEGTLGAPIIPRTSSKYFNFTTEDHKMVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPFPSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSMNSE--NQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLES-ANLTANQHSDVICQSEPDDSFPSS----GSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKPRRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKGRKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAPFLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDGTGVLEAYLMD-SDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYNVTNGTDNQICYQIFDTTVAEDVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0D5-1", "uniprot_id": "E7F0D5_DANRE", "id": "E7F0D5-1", "name": "Protection of telomeres protein 1", "aln": "MPVEKVNNSSDLDTKVPSCLQLTSIGQLTLTSDPSHRCVKARVLRKGPVISCAQRDGLEMLRAEIREEDPLQSTTEHTSINVIFFDTLAKDFSQSVKQGDIVLLANFTISKSPTFLRDKLHPCQLEMDNKDACVYVCPSAIPGPSSSEAKYVYVPLNKLKSKTLVNVYGVVTFFKQPFPSKGSDYCTTLKITDQSDVKVICTIFCKKLEDHPLIFRVGDIIRLHRFKAEAFRDSITLINTFGWSTVTFNGIIDSPIVPRTSSKSFFYGEADKRRVQELRQWAANQSLCSDLNTSLSSVQPHMYFDFTCQLLAKAVMHSGCILLKVWDGTRCQLPLLQVAVPPDELEGECTLAKDKMNLTANVLVYDNHLEVARDLKPGAFLRFYNLRALLQKVPGQLPDQ-PEHLGFHLHGGTVYGRGLRSLPAETPDLLSLKSVLEKHVDLDEHEEVNDGTLLEIWYTPPESIVLPNDENPGAEENAG-PAYTVQTCEHNTQRITLAQVKRSTPPLSCHVRARVKKYLPQQLYQCLKLFCSKCKTMKDVPDDSAVANIFLESARDN----QPCDEQWAATSSANSREPGRTISMHVSK-DMVGKSSHMQLIFIEGMTLDEISVLSRDHKNLVPVRSENSKMTRMDLTAPFLFSGKKRYYGCKQCS-RNTFENP-VFTGVETWDEQAVAAVLGVQMMQYRFLIQFELDDVTDTIEALLWEDAERFFHISAVDASGCQDLQDRIQTIMDTIQPPESSLEERPWMDFCLSVYTVKDNDRNKVCYQITNTEIVKQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : * *.*** ** ::.******.*** *: ***:***:.:.*.* ::**: * :*. : * *:*:: ***:*:**:* :.::.. *. *::::**:* :. *: .***** * : *:: *: ** **:.: * .*...** *:*:*****.** :.. .:********: :* :* :**: : . .*. ::******:.**:.:: *.*:*:*.*:: ** .: .. * ******* ****:* ** .. : .**. ** .: : : : * . . *.. : *: * .: :: .*. : ...* . ::**:::.* *::* *.:** *.:*: :::**. . : :: :.* . . : :. :.. : ** :::*. * : : * *::*** * *:. ** ..:.::**** ..: : ::****:.*. ::******* ..::* .* .:** .**: :** *:: * *** *..::: * : ::.**:*.* :. ::** :: *** : ** .:: **:: :. *.*. . .::**** :* :.:: ", "identical_positions": 201, "similar_positions": 224, "identity": "25.64%" }, { "cls_id": "homologset.agr.MGI:2141505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CFF0-1", "uniprot_id": "PAR11_MOUSE", "id": "Q8CFF0-1", "name": "Protein mono-ADP-ribosyltransferase PARP11", "aln": "-------MFHKTEEFFPKKTDSDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JTL9-1", "uniprot_id": "A0A0G2JTL9_RAT", "id": "A0A0G2JTL9-1", "name": "Poly [ADP-ribose] polymerase", "aln": "-------MFHKTEEFFPKKTESDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NR21-4", "uniprot_id": "PAR11_HUMAN", "id": "Q9NR21-4", "name": "Protein mono-ADP-ribosyltransferase PARP11", "aln": "MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:**:*.*.*:.:****************************** ******************************************.*****************************.******.:*****:.*:**********.**********************************************************************:****************************************************************************************************************", "identical_positions": 314, "similar_positions": 16, "identity": "92.9%" }, { "cls_id": "homologset.agr.MGI:2141520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4VAH7-1", "uniprot_id": "HECA2_MOUSE", "id": "Q4VAH7-1", "name": "HEPACAM family member 2", "aln": "MGQDAFMELLRSMVGLSLCKIHLLLIAGSCLGLKVTVPSYTVHGIRGQALYLPVHYGFHTPASDIQIIWLFERSHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFTDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVMKPMVQFHPASGAVEYVGNITLTCQVEGGTRLVYQWRKSGKPISINSSHSFSPQNNTLWIVPVTKEDIGNYTCLVSNPVSEMESDIIMPTIYYGPYGLQVNSDKGLKVGEVFTVDLGEAVLFDCSADSYPPNTYSWIQRSDNTTHVIKHGPHLEVASEKVAQKTADYVCCAYNNITGRRDETRFTVIITSVGLEKLAQRGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKAIRQKLEGRPESEYRKAQTFSGHEDALSDFGIYEFVTFPDASGVSRMSSRSSPASDGVTGQDIHGTIYEVIQHIPEQQQENTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZP99-1", "uniprot_id": "A0A8I5ZP99_RAT", "id": "A0A8I5ZP99-1", "name": "HEPACAM family member 2", "aln": "MGQDAFMELFSSMAGVSLCKIHLLLIAGSCLGLKVTVPSHTVHGIRGQALYLPVHYGFHTPASDIQIIWLFERSHTTPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFTDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVMKPMVQFHPASGAVEYVGNITLTCRVEGGTRLVYQWRKNGKPININSSHSFSPQNHTLRIVPATKEDIGNYTCLVSNPVSEMESDIIIPTIYYGPYGLQVNSDKGLKVGEVFTVDLGEAVLFDCSADSYPPNTYSWIRRSANTTRVIKHGPRLEVASDKVAQKTADYVCCAYNNITGRRDETHFTVIITSVGLEKLAQRGKSLSPLASITGISLFFIISMCLLFLWKKFQPYKVNASVCLFRPESEYRKAQSFSGHEDALGDFGIYEFVAFPDASAVPRMSSRSAPASDGVTGQDFQGTIYEVIQHIPAQQQDDTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MVW5-1", "uniprot_id": "HECA2_HUMAN", "id": "A8MVW5-1", "name": "HEPACAM family member 2", "aln": "MGQDAFMEPFGDTLGVFQCKIYLLLFG-ACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKVIKQKLEGRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVPASDCVSGQDLHSTVYEVIQHIPAQQQDHPE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** : . *: ***:***:. :* ********:****:****************************.** **************************************.******************************* **:**:**.*********:****:*******.*** *.*:*: .*::******:** *.*.********:*** ***********:* *****************************:********:********:*: *** :*****:*****:****** *************:***:***************:****************:************:****. . ***:******:********.********:***.*.*.*:.*** **** *:***::.*:******** ***:..*", "identical_positions": 376, "similar_positions": 59, "identity": "81.21%" }, { "cls_id": "homologset.agr.MGI:2141558", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYI0-1", "uniprot_id": "WDR91_RAT", "id": "B2RYI0-1", "name": "WD repeat-containing protein 91", "aln": "MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAALRDYWSYLERRLFSRLEDIYRPTINKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQNQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIISLHNFLSVLFQCMPVPVILNFDAECQRTNQVQEENEVLRQKLFALQAEVHRLKKEEQQQEE-AAALVQHKLPPYVSSMDRLGDSELALVCSQRPASLSQSPRVGFLSSLLPQSKKSPSRLSPAQ--GPPQAQSSAKKDTFSSQATKGKDPVPGAKDGKSLLSGPVPGEASWTHQRQRRLQDHGKERRELLSTSSSQTQCAEKKLEGSGPEAELCLDLHMGPVEALARVSTAGSEGD--RPEQPFIVLSQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDDMPRILSLACSPNGASFVCSAAAPSLTSQPDSSAPDIGSKGMNQVPGKLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHGCAMSWKAHCGEVYSVEFSYDENAVNSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGLIYKLGSEEKVLENCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMQ7-1", "uniprot_id": "WDR91_MOUSE", "id": "Q7TMQ7-1", "name": "WD repeat-containing protein 91", "aln": "MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAALRDYWSYLERRLFSRLEDIYRPTINKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQNQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIISLHNFLSVLFQCMPVPVILNFDAECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQQEEEAAALVQHKLPPYVSSMDRLGDSELALVCSQRPASLSQSPRVGFLSSLLPQSKKSPSRLSPAQ--GPPQAQSSAKKDSFSSQATKGKDSVPGAKDGKSLLSGPVPGEASWTHQRQRRLQDHGKERRELLSTSSSQSQCAERKPEVSGAEAEPCLELHMGPVEVLARVSTAGSEGD--RPEQPFIVLSQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDDMPRILSLACSPNGASFVCSAAAPSLTSQTDSSAPDIGSKGMNQVPGKLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWKAHCGEVYSVEFSCDENAVYSIGEDRKFIQWNIHKSGLKVSESNLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGLIYKLGSEEKVLENCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4D1P6-1", "uniprot_id": "WDR91_HUMAN", "id": "A4D1P6-1", "name": "WD repeat-containing protein 91", "aln": "MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAALRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQNQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDAECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEE-EEALVQHKLPPYVSNMDRLGDSELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQ--GPPQPQSSAKKESFGGQGTKGKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTS--QCAEKKPEASGPEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TEN6-1", "uniprot_id": "WDR91_DANRE", "id": "Q6TEN6-1", "name": "WD repeat-containing protein 91", "aln": "MASAVERTDDLVREYLIYRGFTSTLKHLDSEIKTDKEKGFRVDKIMDQLQLLIQSCDLTGLKEYWANLERRLFCRLEDVYKPTVSKLRTSLYRFYLIHTVQVKNVEKTQEFFQKQALELQAQAEWRDWFSLPFIPAPEQNPSFSAYFSRQWADTFLVSLHNFLSVLFQCMPLPALLSFDSEVQRITSLQEDNEQLRQTVFALQGES-RLKKDEQ--------MVHHKLPPYVQHMDRLGDTELDLVSSQRNVNMATPSRN-FFSTFLPQGRRAPGRTAPGPQSSPTQSALGRKDAAASMQSSKAKD-----KEVKPPSVSSMTAELSTSHPRQRRHQDHEKERKELFSKHAA--QGSEKKTD-SDPDTQTEAPPDQTDSANQTRVCDVGGAGA----EQPFIKLSQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVVKVWAFNPIMQTKATIMSKSPLLSLEWAAKPDRLLLLGSGVGTVKLYDTDAKKCLYEMTIDDVHPRILSLACSPSGTSFVCSAAAHSGAVME--SEP----RGSAPVSGQLLLWDTKTVKQQLQFALEPGPVAINCTAFNHNGNLLVTGAADGIIRLFDMQRYESALSWKAHDGEVYSVEFSYDENTVFSIGEDGKFVQWNIHRCGVKQSEYSLSQDAVGPFVLSGYSGYKQVQVPRGRLFAFDSEGQHVLTCSSTGGNIYRLNKAEAGLESVLSLAGHKAPVVTVDWCSAMDCGTCLTASMDGKIKLSTLLAQKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE12-1", "uniprot_id": "Q9VE12_DROME", "id": "Q9VE12-1", "name": "ARMC9 CTLH-like domain-containing protein", "aln": "-MAQVAFLDNLLREYLVFRGFSSTLKALDLEQRTEKDQHFRAERILEQFNNAVQASDLQALRSLWFHLDNNIFSKLEHTYAVAVKKLENSLLKYYLVTAYSSNRPEKVSEFFNKLAGDLQQQSEWKDWFYFPFCKNAEESPTFALFFTKQWQDTLLLSLRNFLTTVYQCLPQPTFVRAEQEAAHMQRLSEDNAGLRTRVLNLQQELNQMTQQQS---------------------------------------------------------------------------------------------------GTAAASGSSLGGGVDNGARRRSVYRQQQSLSDILPFDISPPGHIVDDFCIIASEANSVSQASDAQARSLKQLIRNIGSGS------------SPVMGRKDQTASSLGEKSTKRRSGSLGRSWI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:*:****::***: **: ** * :::*:: **.::*::*:: :* ** .*:. * *:..:*.:**. * :: **..** ::**: : . :. :*..*** * * :** *:**:*** :** .: .*:*: :*::** **:::**:***:.::**:* *.:: : * : :.*:* ** :: ** * ::.:::. .. . . . *:* : :. :::. : . .::: : * . *.:..: ..: ** .**. . : ", "identical_positions": 84, "similar_positions": 114, "identity": "11.17%" }, { "cls_id": "homologset.agr.MGI:2141599", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7W5-1", "uniprot_id": "SEN2_MOUSE", "id": "Q6P7W5-1", "name": "tRNA-splicing endonuclease subunit Sen2", "aln": "-----MAEAVFRAPKRKRRVYESYESPLPIPF-------GQDQGPRKEFRIFQAEMISNN---VVVRGTEDMEQLYGKGYFGKGILSRSRPNFTIANPTLAARWKGVQTDMPIITSEKYQHRVEWARDFLRRQGHDESTVQKILTDYTEPLELPCREEKEETPQHEPLSSKADSSLEGRVEKDELPVTPGGAGQSDDLPGLGTHSDCLQEGPGHATLAAASPSSHNGHVAEDPEVLP------QETLVPQGGLWPEASSQAA-----GEKRAAHEYVLIEEELCGAQEEEAAAASDEKLLKRKKLVCRRNPYRIFEYLQLSLEEAFFLAYALGCLSIYYEK-EPLTIVKLWQAFTAVQPTFRTTYMAYHYFRSKGWVPKVGLKYGTDLLLYRKGPPFYHASYSVIIELLDDNYEGSLRRPFSWKSLAALSRVSGNVSKELMLCYLI-----KPSTMTAEDMETPECMKRIQVQEVILSRWVSSRERSDQDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M954-1", "uniprot_id": "SEN2_RAT", "id": "Q5M954-1", "name": "tRNA-splicing endonuclease subunit Sen2", "aln": "-----MAEAVFRAPKRKRRVYESYESPLPIPF-------SQDQSPRKEFRIFQAEMISNN---VVVRGTEDMEQLYGKGYFGKGILSRSRPNFTISNPKLAARWKGVQTDMPIITSEKYQHRVEWARDFMRRQGHDESTVQKILTDYTEPLEPPYRERKGESPQHEPLSSKADSSLEGREGKDELSVTTGGAGQSDDLQGLNTHSDCRQEGPGHATLTVASPSSLNGHAIEDPEALSQIPCCSQEALGQQDDLWPEASSQIA-----GESRAAHEYVLIEEELCDVQEG---AAPHDELLKRKRLVCRRNPYRIFEYLQLSLEEAFFLAYALGCLSIYYEK-EPLTIVKLWQAFTAVQPTFRTTYMAYHYFRSKGWVPKVGLKYGTDLLLYRKGPPFYHASYSVIIELVDDNFEGSLRRPFSWKSLAALSRVSGNVSKELMLCYLI-----KPSTMTNEDMETPECMRRIQVQEVILSRWVSSRERSDQDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCE0-1", "uniprot_id": "SEN2_HUMAN", "id": "Q8NCE0-1", "name": "tRNA-splicing endonuclease subunit Sen2", "aln": "-----MAEAVFHAPKRKRRVYETYESPLPIPF-------GQDHGPLKEFKIFRAEMINNN---VIVRNAEDIEQLYGKGYFGKGILSRSRPSFTISDPKLVAKWKDMKTNMPIITSKRYQHSVEWAAELMRRQGQDESTVRRILKDYTKPLEHPPVKRNEEAQVHDKLNSGMVSNMEGTAGGERPSVVNGDSGKSGGVGDPREPLGCLQEGSG----CHPTTESFEKSVREDASPLPHVCCCKQDALILQRGLHHEDGSQHIGLLHPGDRGPDHEYVLVEEAECAMSERE--AAPNEELVQRNRLICRRNPYRIFEYLQLSLEEAFFLVYALGCLSIYYEK-EPLTIVKLWKAFTVVQPTFRTTYMAYHYFRSKGWVPKVGLKYGTDLLLYRKGPPFYHASYSVIIELVDDHFEGSLRRPLSWKSLAALSRVSVNVSKELMLCYLI-----KPSTMTDKEMESPECMKRIKVQEVILSRWVSSRERSDQDDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IP11-1", "uniprot_id": "Q8IP11_DROME", "id": "Q8IP11-1", "name": "tRNA-intron lyase", "aln": "--------MQFTFECKRKRCFNKNANFTPLPS-------GQDGER------YKGRFTGLS---VEIVDPEQAKSLHDNGCFGKGSKSRGGP---------------------------------------------------------------------------------------------------ASGDEN-----------------------------------------------------------------------------------------------------------------------ETLFLGMEESCFLAHYLNVLDITNSAGYLMDFCMFVEVAKEHNEKFVENLASYVYLKSKNWVIKSGIKFGGDFLIYKQSPRLYHASFLVIVQKPGD------TDHYQSKNLKGVQRVAETSDKDVLLLTVQ-----PPKKISSSRDLQEATVTETIVRRFNYLTFVQSKQQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16658-1", "uniprot_id": "SEN2_YEAST", "id": "P16658-1", "name": "tRNA-splicing endonuclease subunit SEN2", "aln": "MSKGRVNQKRYKYPLPIHPVDDLPELILHNPLSWLYWAYRYYKSTNALNDKVHVDFIGDTTLHITVQDDKQMLYLWNNGFFGTGQFSRSEPTWKAR---TEARLGLNDTPLHNRGGTKSNTETEMTLEKVTQQRRLQRLEFKKERAKLERELLELRKKGGHIDEENILLEKQRESLRKFKLKQTEDVGIVAQQQDISESNLRDEDNNLLDENG-------------------------------------------------------------------------------------------------DLLPLESLELMPVEAMFLTFALPVLDISPAC--LAGKLFQFDAKYKDIHSFVRSYVIYHHYRSHGWCVRSGIKFGCDYLLYKRGPPFQHAEFCVMG------LDHDVSKDYTWY--SSIARVVGGAKKTFVLCYVERLISEQEAIALWKSNNFTKLFNSFQVGEVLYKRWVPGRNRD-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : : . . : : . :: * .:* **.* **. * .. * * * *: **.. * *.* .. .* . * : :*:.* : *:*:* * *:*::.* : **.: *: .: ** .* .:* : . . * .. :* .::: ", "identical_positions": 38, "similar_positions": 56, "identity": "7.72%" }, { "cls_id": "homologset.agr.MGI:2141635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VN0-1", "uniprot_id": "CP100_MOUSE", "id": "Q80VN0-1", "name": "Cilia- and flagella-associated protein 100", "aln": "MAFKARSSRFSVKMVEDTGGSQDLINNSFSSFIEEKSKESKKNKGNVTISDRSSNPFHISRDMDYFLLREQEQNQAIAEREQKKILRVHQKMTYASKVSAKHTSLRRELQLEDEMEQQLLNAEAKEMNCFRENNDWKLAMTRERKREPETLNDYMEKRRSMFLLQYALAMKRNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRNSVQAMRMAEKETKIKTEKIVEIRELTAQITSIKSEISKFEDTLKHYKIYKEFLYKLSPKEWLDEQQEKHLAFKRAKESSELTRNNSTAILFGDKGSGSKSKTAFLWK-EVPGLKKVTKTGRLVKA-LSSSIQSLPQVGQLTQLSPHSELDSRLSSTMFP-SQDDTDSDGEELALYFTEPQQLLDVFTKLEEENLSLIQNTQEMEETLDELNVTLKNTQIRMDKEVNLLKQWIASMMISISKEEESAAELELKARVFHFGEYQGDQQDTMLESLNHKVLEVYRKCVGMQQEANLGTVQMLTVVERQLDELLENLERVPQVKIEQAEKAKERERRMRLREEKAMMQKQLQEERLQRARARAQAKIKKKRGRKLISRSHPPVIKVKEVREQTLINKDKEEMLFFFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZEI2-1", "uniprot_id": "D3ZEI2_RAT", "id": "D3ZEI2-1", "name": "", "aln": "MTFKAQS-KFSVKIFGDRG-SPDFMDNSSSSFIDNRKKDSKKNKGSVTFADSSTNPFHISGDVDFFLLREQERNQAIAEREQKKILRVHQKMTYASKVLAKHTSLRRELQLEDEMEQQQLNAEAEEMNEFRDNNAWKMTVTREKKKEHETLNDYMEKKRSMFLLQYALAMKHNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRNSVQAMRLAEKETKIKTEKIVEIRELTAQITSIKSEISKFEDTLKHYKIYKDFLYKVSPKEWLDEQKEKHLALKRAKESTELK-----SILVGDKGSGIKSKPSSLWK-EVHSLKKITKFSRPGKT-LSSSTQSLPQVGHP---SQHSELDSTLSSSTLP-SQDETDSDGEELALYFTEPHQLLDVFTKLEEQNLSLIQNTQEMEETLDELNVTLKNTQIRMDREVNLLKQWISTMMISISKEEESAAELELKARVFHFGEYQGDQQDKMLESLNHKVLDVYRNCVGMQQEANLGTVQMLTVVEHQLDELLENLERVPQIKIEQAEKVKERERRMRLREEKARMQKQLQEERLQRARARAQAKIKKKRGRKLLCRSHPPVIKVKEVHEQTLMDKDKEEMLFFFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q494V2-1", "uniprot_id": "CP100_HUMAN", "id": "Q494V2-1", "name": "Cilia- and flagella-associated protein 100", "aln": "-MSEIPSTIVSKNMTNDKNSLESMNISSSSSTEENPKKQARKNEEHG--PDPSANPFHLSGDVDFFLLRDQERNKALSERQQQKTMRVHQKMTYSSKVSAKHTSLRRQLQLEDKQEDLEARAEAEHQRAFRDYTTWKLTLTKEKNVEPENMSGYIKQKRQMFLLQYALDVKRREIQRLETLATKEEARLERAEKSLEKDAALFDEFVRENDCSSVQAMRAAEKETKAKIEKILEIRDLTTQIVNIKSEISRFEDTLKHYKVYKDFLYKLSPKEWLEEQEKKHSFLKKAKEVSEASKESSVNSTPGDKGPGIKGKASSMWAKEGQGTKKPWRFLQTMRLGRSPSYLSSPQQGSQP--SESSGGDSRGSNSPIPPTQEDTDSDGEEPQLYFTEPQQLLDVFRELEEQNLSLIQNSQETEKTLEELSHTLKHTQIRMDREVNQLKQWVTTMMMSITKEEDTAAELELKARVFHFGEYKGDQQDKLLESLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHVPQVKIEQAERAKEKERRIRLREEKLQMQKILQEEHLQRARARAQAEIKKKRGRTLVCRSRPPAHRIKQQSEHTLMDKEEEELLFFFT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .* :: * . .: .* ** :: .*:::**: .* *:****:* *:*:****:**:*:*::**:*:* :********:*** ********:*****: *: .***:. . **: . **:::*:*:: * *.:..*::::*.******** :*:.****** ***:** ******* *****:*****:**** .****** ****** * ***:***:**:**..******:*********:**:****:******:**::** :*:*** :* . ****.* *.*.: :* * . ** : : : *.* * ** * * * ** *.: :* :*::******* ******:****** :***:*******:** *:**:**. ***:******:*** ****:::**:**:***::****************:*****.:***** ***:***:*.* *************::*:**********:***:******:.**:***:****** *** ****:**********:*******.*:.**:**. ::*: *:**::*::**:*****", "identical_positions": 370, "similar_positions": 139, "identity": "60.06%" }, { "cls_id": "homologset.agr.MGI:2141640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGP6-1", "uniprot_id": "D3ZGP6_RAT", "id": "D3ZGP6-1", "name": "", "aln": "-------------------------------------------------------------------------MAPPQALVCLGACSGDESLNMQLCEVHPSRQAWSGTPDDCPDFPSGFCRVLRRNLRREVLASKVTWKR-LRAQTYREAGRASMAG---ARAALLLL----LLLLHLWNLALAA--RGGEVS-------------------------------------KGQPRLADVLES---QQQAPSHSLVPCE-----------------------TQQQQLCPLEERLERLEADVTYLRKQNRDLQARLLQLESCKCCSTSPQCWGPGHPCPEGARWEPDACTACVCRDGTTHCGPQPNLPHCRGCSHNGQSYGHGETFSPDACTTCRCLAGAVQCQGPSCSELNCLESFTPPGECCPICRP--GCEYEGQLHQEGTSFLSTSNPCLQCSCLRSLVRCVPVKCQPSPCPNPVLRPGHCCPVCQAS------------------------------------------------------------------------------------------------------------------GCTEGHSHRDHGQEWTTPGDPCRICQCLEGHIQCRQQECASLCPYPARPLPGTCCPVCDGCFLNGREHSSGEPVGSQDPCS-SCHCANGSVQCEPLPCPPAPCRYPGRIPGQCCPVCDGCKYQGHEYRSQETFTLQENGRCLRCTCQAGEVSCEE--QDCPVTPCVHTASGP----QLCSACVLNGEEFAEGIQWEP-DDQPCTTCSCQDGVPVCRAALCSPVPCQHPT-QPPGACCPSCESCTYHG----------------------------------------------------LVYSNGQNFTDVDSPCQTCYCEDGTVRCSVINCPSLTCAKPQNGPGQCCPKCP---DCILEAQMFVDGERFPHPRDPCQECLCQEGQTHCQLRACHSAPCGHPLPSTCCRNDCKGCAFGGKEYLNGADFPHPTDPCRMCRCLSGNVQCLARRCPPLACPQPVLTPGDCCPQCPDAPA--GCPQSGNTVLVRHQEHFFQPGDPCSRCLCLDGSVSCQRLPCPPAPCAHPRQGACCPSCDGCLYHGKEFANGERFPSPSVTCHVCLCWEGSVNCEPRACAPAQCPFPTREDCCPACDSCEYLGVSYLNSQEFPDPREACNLCTCLGGFVTCTRRPCEPPACSHPLILPKHCCPTCQGCLYHGITAALGETLPDPLDPTCSLCTCEEGSMRCHKKPCPPALCTHPSPGPCFCPVCRSCLFQGQEHQDGEEFEGP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGSCERCRCLAGQVSCMRLQCPPLPCLLQATEPGTCCPRCTGCRVRGEEHPEGSSWVPADSPCSSCMCHKGIVTCAQVQCVSACIWPQQGPSDCCPSCSGCEHEGRKYEPGESFQPGDDPCEVCICELKGKGPPSLHCRRRQCPSLVGCPPSQLLPPGPQHCCPACAQALSNCTEDLLG-SELVPPDPCYTCQCQDLTWLCTHRACPALSCPLWEHHTTPGSCCPVCKD------------------------------------------------------------------------PTGSCSHQGRWVASGEHWIVDACTSCACVAGTVHCQSQRCRNLSCGRDEVPALSPGSCCPRCLPGLASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSEDFSVHVTNDDRGRRGVAWTQEVAVLLGTVAVRLLQGRTVMVDQHTVTLPFLREPLLYIELRGHTVILHAQPGLQVLWDGQSQVEVRVPSSYRGQTCGLCGNFNGFAQDDLQGPDGRLLPTEAAFGNSWKVPKGLGPGRPCSAGREVDPCRAAGYRARREANARCGILKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADTCLCDALEAYASHCRQAGVTPVWRGPTLCVVGCPVERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEGHCISPEACPSVLLTGG-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U492-1", "uniprot_id": "KCP_MOUSE", "id": "Q3U492-1", "name": "Kielin/chordin-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MAG---ARAALLP------LLLHLGSLALAA--RGGEVS-------------------------------------REQPRLADAIS----QQQAPSHSLVPGE-----------------------THQQQWCPLEERLERLEAEVTDLRKQNRELQARVVQLESC-------ECWGPGHTCPEGARWEPDACTACVCRDGTAHCGPQPNLPHCRGCSHNGQSYGHGETFSPDACTTCRCLAGTVQCQGPSCSELNCLESFIPPGECCPICRP--GCEYEGQLHQEGSSFLSSSNPCLQCSCLRSLVRCVPVKCQPSPCLNPVPRLGHCCPVCQAS------------------------------------------------------------------------------------------------------------------GCTEGNSHRDHGQEWTTPGDPCRICQCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHSSGEPVGSQDPCS-SCRCTNGSVQCEPLPCPPAPCRYPGRIPGQCCPVCDGCKYQGHEYRSQETFTLQENGRCLRCVCQAGEVSCEE--QDCPVTPCVRSASGP----QLCSACVLNGEEFAEGIQWEP-DDQPCTSCSCQDGVPVCRAVLCSPVPCQHPT-QPPGACCPSCDSCTYHS----------------------------------------------------LVYANGQNFTDVDSPCQTCYCEDGTVRCSLINCPFTTCAKPQNGPGQCCPKCP---DCILEAQVFVDGERFPHPRDPCQECWCQEGQAHCQLRACPSAPCVHPLPGTCCKNDCTGCAFGGKEYPNGADFPHPTDPCRLCRCLSGNVQCLARRCPPLSCPQPVLTPGDCCPQCPDAPA--DCPQSGNMVPVRHQEHFFQPGDPCSRCLCLDGSVSCQRLTCPPAPCAHPRRDACCPSCDGCLYQGKEFASGERFPSPNVACHVCLCWEGSVKCEPRTCAPAQCPFPTREDCCPACDSCDYLGVSYLSSQEFPDPREACNLCTCLGGFVTCTRRPCEPPACSHPLIVPEHCCPTCQGCLYHGITAALGETLPDPLDPTCSLCTCEEGSMRCQKKPCPPAPCAHPSPGPCFCPVCRSCLSQGREHQDGEEFEGP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGSCERCRCLAGQVSCTRLQCPSLPCLHQVTEPGTCCPRCTGCLARGEEHPEGSSWVPADSPCSSCMCHKGIITCAQVQCVSACIWPQEGPSDCCPQCSGCEHGGRKYEPGESFQPGADPCEVCICKQKREGPPSLHCSRRQCPSLVGCPPSQLLPPGPQHCCPTCAQALSNCTEDLVG-SELVPPDPCYTCQCQDLTWLCTHRACPELSCPLWERHTTPGSCCPVCKD------------------------------------------------------------------------PTQSCMHQGRWVASGEQWAVDACTSCSCVAGTVHCQTQRCRKLACSRDEVPALSPGSCCLRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHGEDFSVHVTNDDRGRRGVAWTQEVAVLLGTVAVRLLQGRTVMVDQHTVTLPFLREPLLYIELRGHTVILHAQPGLQVLWDGQSQVEVRVPSSYRGQTCGLCGNFNGFAQDDLQGPDGRLLPTEASFGNSWKVPKGLGPGRPCSAGREVDPCRAAGYRARREANARCGILKTSPFSHCHAVVPPEPFFAACVYDLCACGPGSSSDTCLCDALEAYASHCRQAGVTPVWRGPTLCVVGCPVDRGFVFDECGPPCPRTCFNRHIPLGELAAHCVRPCVPGCQCPAGLVEHEGHCISPEVCPPVLLTGD-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWJ8-3", "uniprot_id": "KCP_HUMAN", "id": "Q6ZWJ8-3", "name": "Kielin/chordin-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MAG---VGAAALS------LLLHLGALALAAGAEGGAVP-------------------------------------REPP-----------GQQTTAHSSVLAG-----------------------NSQEQWHPLREWLGRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICRP--GCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQG--------------------------------------------------------------------------------------------------------------------CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCS-HCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEE--QECPVTPCALPASGR----QLCPACELDGEEFAEGVQWEP-DGRPCTACVCQDGVPKCGAVLCPPAPCQHPT-QPPGACCPSCDSCTYHS----------------------------------------------------QVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP---DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPG-AAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLG-SELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRA------------------------------------------------------------------------PTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQVLLTGDQPLGARPSPSREPQETP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q752-1", "uniprot_id": "F1Q752_DANRE", "id": "F1Q752-1", "name": "", "aln": "MELKCSVGDLLFLSFLWNVLCVQTHLDANFPRGDDTVINLLEALNITRSPHGVSKVKGSDPETPAWRLRSSTHLILPQDLSKNLFSTSQGVLGLHLLGRQTKNSEITLISVSNQQQERRPLLELISNTQSDWLQMRFRSGDGLQTEVLKLPGGSPFTGGGWVRMALSVEPRQMLLFVDCQEAVVLKLKGGGRILSLDFTHDVQVTFSRAAGNTTSKFSGSWQIAELSTRTYERRPWFCDNITDSLPDTIHPTLSTVPAVPDLSMMRDEAGRGDGVLSTTGPSESDVRFGDLERNLHGIMTMLEMLKRQNTELQARVEFLETCECIKR--KCVWEGRQVDEGSHWSPDIRTVCSCSSGRVQCN------RSSECSFQSRIYSDGEVFSPDECSRCKCEYGRVECDVNPCPSQTCEEPSVQR-PCCSVCQTSLRCEHEGQVYENGHEFVSRSNPCLSCICSNSRVSCNTIQCPSTPCPNPYRRPGECCPTCSACDVDGRPYNGSFSTVDGCQTCTCQGGNQECVDVQRCPQTCQDGVKPPFGSCCRDCSRCYFDGQIVLDGVSFQDSSDPCKHCVCSAGNIVCNPELCPELPCTLLETVGGQCCPRCRSCVQENVWHLHGSQWRHPSDHCSTCTCTEGKIQCEHERCNVPCRNPASPPPGSCCPVCEGCNLNGLDVPNGMPLPSGPVCEGSCRCENGNVICDRLPCPPTPCYNPVTPPGECCPRCTECVYEGEVYEDGQTFISRQD-PCLRCQCLGGQVSCDPPGSSCPPPTCTHPTKPPTQCCATCNTCEYEGRIYGDGEEFRPPGGGPCVLCTCKGGNVRCHQERCPPTNCPVPTPAPPNQCCPACRGCVWNNNQYEEGSTWADGEQMCSCVAGQVTCRLNCPTPESCLEPIVTGGDCGQCQYGEYVYENGQSFQDPQDPCVTCTCQDGQTRCVLPACPAVTCVNPYTSPGECCPRCPPVQDCEYDNRIITNGDTFPNPGNQCLDCVCTDGHVDCGNHECPKPNCNYPRPGTCCQNNCNGCNYAGNEYPNGMEFPHPVDNCRMCRCTNGNVQCLMKRCPAVHCDNSFVQAGECCRQCPAPPA--DCIVEE--QSYRHMQRFSHPTDSCQSCTCTNGTPSCRRRPCPSATCSHPIIQECCRTCDGCLYHGREHANGATFADPSDSCRTCVCRDGTVTCHSNQCQRIACPFPVQDQCCPHCNGCMYAGVEYLNGQEFADPSDHCAHCICSNGHVTCNTKPCHNPGCTYPTTRPDQCCPVCDGCQFEGRVYVDGELFPS-STTSCEECRCSRGEVECSPKSCPIVSCPHPERDPCLCPVCEGCQFNGRDCGNGERFPDPSDPCRSCACLDGSVSCSPVSCPEVFCKRPVRPPGECCPVCSGTCEHLGQVYEDASTFIPADDRCSTCTCLSGVVLCEKKMCSKKCTHPVRTRLCCPVCDACLYEDKKYRNTESFIDPWDPCRTCVCRDGSVSCSAITCPAVSCQNPITPAGKCCPECRVCVQYDQQYVDGESLTLPADPCLKCTCVAGEVKCVSPRCKTLSCVHQLTDPGSCCPRCRGCIYDGVERQEGSTWFASAGLCMSCMCVDGVTTCSEVHCLSTCINQITVPGECCPVCADCVFEGRVYGPGESFQPSEDPCQICTCEVMPDGEQHLRCYRKQCPSLVDCPKHNILHSSSDSCCPVCTQPLSNCTATLIGNEVLATDDPCFTCQCKDLTWTCVHRGCPPLSCSPSDQHTPPDSCCPICDVCVLEGSNTRVPDGHRWTDKENECTTCICNKGHIECDLQECAPLQCPDGSVKVKNPGKCCQECTEVVDVVYIYPSAECVYEGQIYRDSDQWEVDECTTCTCVNGDVHCQTQRCPTLTCASDETPALVPGMCCPHCIPHPATCVVFGDPHYRTFDGKMVHFQGTCTYVLAQDCEGGDFSVHVSNEDRGRKGVSWTKEVTVFIGDVVIQLYQDWIVKVDYEPVSLPYLKEPYIYLERKTNTILLNTNVGLKVLWNGRSHLEVSVPGTYKNHMCGLCGNFNNYPQDDMKLRNGQIATSEAAFGNSWKVGNGN-SSVQCPDVRNINPCKEAGYSARKTANSRCAVLKSPVFERCHKLVLPEMFFASCVYDLCACG--SNMDDCLCDVLEVYASECREAGIIVQWRTPTLCAVGCPLDRGYVFDECGPPCPKTCFNKDVPLGVIEAHCFKPCVPGCQCPAGLVEHNAHCIAPEKCPKIIHDNL-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* . * *::. .: ** : . * .: * * : : *.. * : : : *:.** :**:*: **:* :* *: **::*.** *.* * .* .:*. :. ** :.: *..**.**** *: *:* * *:*: .*.. .* *. **.:*:. *::***::::* *:* *****.* * .* * * .::* .:** :* * *.***.*.. *.: **.:* *.* * * * **:***.:..* * ** * **:*****:** *** : .* *: * *. *:* **.* *: *****.** * **:*** * * *:*. *.. :** :: *:** * .*:***: ..** ..*. .:. * :* :*. :.:* ::.* .. **. * *:.* * *.*. * ** **. ***:* .*.::. ** ***.* * :.** :* *:** . * : ** **..* ..**:***:** ** : .::.:*: *.:* : * :* * :*:..* : * . * :* *.*** *:*.** :.*:** .* :**** * **:*** .****** :** .: * :..: .*:** *** .** .* ** : * * *.* * * :*: **:* .**.*.*:** ** :******:*:*.*.* *..*. :*: *:* :*:*.*... * ****.: :*** *:.* * * .**..***.** : * * * .*.*** :**. *.*::* . :***.*:** :.* . . ** :*. .:*. * *..*.:.* *.** . *.**. .**:****..* :*:: :**.* .* ..* * * **:*.* :* .*.* * *: *:***** ** * *: *** *... . * **:* .*: **:.::*:*:* * :*** *:.* . ** * *******. ***::* *: .* *:* *:******.** ::* ...: ***.*::.****: *:* . *.. ***:****:**** * *:.** ***. ::**.*.****:* *: .* ::*: ..::* ** **:*:*: * *:**:*** *:*. *:.*** ** ** :*:* *:*:.***********:::****:*:****:**.. ******:*:**** **:**:**:*::* :.::* *. * ** ..*:**:*:** :*:* : :*::*::: **:***:*:*::** **.:*:.: ********.:.***:: :* : .:**:*****:* :* .. *. *:::**: *** **: **:**.:**:. *.:** :* ** ***:********* *. * ****.**.***.**:**: ** ****.****::**:**********:****:.:*** : ***.:***************:.***.** ** :: . ", "identical_positions": 684, "similar_positions": 444, "identity": "30.6%" }, { "cls_id": "homologset.agr.MGI:2141656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AVA2-1", "uniprot_id": "A0A8I6AVA2_RAT", "id": "A0A8I6AVA2-1", "name": "", "aln": "--MALRPQRTFRRRQVDSSDSDSD--------GTKEQSAEEPAESGRPSAGGR-------------------TEGAERPRGARSARGRGR---------------------------------VWASSRRSPGAASRGDGGAECRTADLSTDEE-----------------------------------------------EGELPLPENKDDESPSSDSSCSLEEKEVSPIVKIPDAAFIQAARRKRELARTP--GDYISLDVNHP--STTSESKRSNGEDSESDPDDHEKRILFTPKPQTLRQRMAEESSIRNEDSSEESQEDESQDTWEQQQMRKAVR-------------------------------------------------ITEGQSIDLLHSSKSQTLKKFDSSISFAPVNLEIIKKQLNSRLTLLQDSHRSHQREYEKYEQDIKSSKT-AIEKLESGPDQALNYKFYKGMKIYVENIIDCLNEKISSIVELESSMYTLLLKHSEALLKRRQDELKCESSYLQQLSRKDETLASGSLALDEKDQRILEEIEARRVQRRQARVLSGNCDHQEGTSSDEELSPAEMTNFHKRQGDILQDCKKVFEDVHDDFCNVQNILLKFQQWREKFPDSYYEAFVGFCLPKLLSPLIRVQLLDWNPLKMDSMGLDRMPWFTAITEFMESGMEDVGKEDGS-DKKILSAVINKTVVPRLTDFVEMIWDPLSTSQTRILTVHCRVAFEQFAS-ETEVSKSKQDLLKSVAARMKKSIEDDVFIPLYPKSSEEGKMSPHSKFQERQFWGALKLFGNILLWNGLLPDDILQNLGLGKLLNRYLIIALTNAIPGPDVVKKCSQIAACLPDKWFENSAMRTSLPQLENFVQFLLQSARKLSTT--EFRNELNGIILILVKVKALSQAESLTEEHRLEPLTAQTAGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKT3-1", "uniprot_id": "GCFC2_MOUSE", "id": "Q8BKT3-1", "name": "Intron Large complex component GCFC2", "aln": "--MALRPQRTFRRRQVESSDSDSDSD------GAKEQSAEEPA-----SAGGR-------------------TEGAERPRGARSARGRGR---------------------------------VWASSRRSPGAAPRGDGGAECRTAELSTDEE-----------------------------------------------EGTHTLTGSKGDRSPSSDSSCSLEERDVSPIVEIPDAAFIQAARRKRELARTP--GDYISLDVNHS--CSTSDCKRSNEEDPESDPDDHEKRILFTPKPQTLRQRMAEETSIRSEESSEESQEDENQDIWEQQQMRKAVR-------------------------------------------------IPAGQNTDLSHSSKSQTLKKFDTSISFPPVNLEIIKKQLNNRLTLLQESHRSHQREYEKYEQDIKSSKT-AIQNLESASDHAQNYRFYRGMKSYVENIIDCLNEKIVSIVELESSMYTLLLKRSEALLKRRQDELKCESSYLQQLSRKDETSANGSLAVDEKDQRILEEIEARRMQRRQARELSGSCDHQEGMSSDDELSPAEMTNFHKCQGDILQDCKKVFEDVHDDFCNVQNILLKFQQWREKFPDSYYEAFVGFCLPKLLSPLIRVQLLDWNPLKMDSIGLDKMPWFTAITEFMESSMDDIGKEDGS-DKKILAAVINKTVVPRLTDFVETIWDPLSTSQTRSLTVHCRVAFEQFAS-ENEVSKNKQDLLKSIVARMKKSIEDDIFIPLYPKSSEEGKMSPHSKFQERQFWGALKLFRNILLWNGLLPDDTLQDLGLGKLLNRYLIISLTNAVPGPDVVKKCSQIAACLPERWFENSAMRTSIPQLENFIKFLLQSAQKLSSS--EFRNEVSEIILILVKVKALTQAESLREERPLEPLPAQSTGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16383-1", "uniprot_id": "GCFC2_HUMAN", "id": "P16383-1", "name": "Intron Large complex component GCFC2", "aln": "--MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGR-------------------AQVAGLPHRVRGPRGRGR---------------------------------VWASSRRATKAAPRADEGSESRTLDVSTDEE-----------------------------------------------DKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKRELARAQ--DDYISLDVQHT--SSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVK-------------------------------------------------IIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKS-TIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKKESSS-DKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLWNGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSIPQLENFIQFLLQSAHKLSRS--EFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5P2-1", "uniprot_id": "A0A8M2B5P2_DANRE", "id": "A0A8M2B5P2-1", "name": "", "aln": "-MFNKKPRRNFRQRKNESSDEDDNGKLAAGEGGKDADLKADLPSKAGISSSSREARE-------------CDSSEAEEEASVSALQTKDRKLHTDSKTLSFSDDKDSTEGGFQVKRSVNREVLFQARKKEDSPAPATSSQGKKSKDVSLSDSDS-----------------------------------------------DASAEDIPPDSDEETCSTMSSSS-ASSLPQRVIIPDARKIHAAKEKRRQARAQ--QDYISLDSPRTPGSLKEDELSDKEQDSDNDLDDHERRIEFAPKPKTLRERMAEKMGSDSEESFSDSQEEEEQQMWEEQQIGKGVKRHQCFK-------------------------------------------DLSLYSQKEWHAPKAARQKRVEIPETLPVVSIGVIKKRITGKLDSLREVHRAREAQLRRMQLDVEMAKT-SLEGLEN-NNADEQLRFYRTMNVFSQNLLECLSEKMALINSVELDMHGLYIDQAEALLSQRREALQEESSRIQKLTYNTDSHSNGDTAGDCS-----------------PTQQSLSEDDIGCVPCDWEPTVEQKEEIESKRAALLKKAQEVFADVQNEFWDVKKILSRFDEWRVSFKDSYNNAYIGLCLPKLLAPLIRHQLIGWNPLQAESEDFEALPWYCAVERFCHG--QGYEESENM-DKTTLPTIIEKTILSKVQGFVELVWDPLSAQQTRTLTTLCRRIQHDYSVFNGEQSKPVKAFVEAVIQRLRTAVDDDVFVPLYPKKFLEDKRSPQFQFQNKQFWSAVKLLGNMALWGGLIPEHILKELMLEKLLGRYLMITILNESDPKHTVQKCKKIAGCFPESWFIDLNTGSSLPQLQNFSKHLLQTAHLIFKDNKDSRGLLSDVLFVLKIIKAHDSIRTITEKYNCKDLLKAL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI54-1", "uniprot_id": "Q9VI54_DROME", "id": "Q9VI54-1", "name": "GCF C-terminal domain-containing protein", "aln": "MSLFRKPKKIQRRVFSSNADEEEDGASLDPDAEMEAPPPPIISGKREKEKSRKAIKPQEDNSKPKALLSFADDEDDGEVFQVRKSSHSKKVMRMLDKERRKKKREERAENSGHPGGENGSTQHLESSGGPSSGPPNSNSNPANAGRYKSASDQSKSKKSDNHMIQTEIRTDDFVLVVKKSETPEAILNGRAALCAGREDMSDEEDQQSEDGGHDKTRHRFSKPEHLKQMLESGSIPDAAMIHAARKRRQRAREQGAGDYIPIEEPKE---PAKLSNRLPCEDVEGDQSDDEERMDMNDITGRKEREERREQFYAVENDSTDGDSDREMNEWENQQIRKGVTAAQLVHSQHETVLSRFMIKPAPSGIGTGMDDGDSTAAQSTSTLLEQAYAKNALERTNLAAAVRSSVKTKKEKAKATALRTPQEILAAIQSRLSELKERSADHSASMARISTELKALKLQQLECQQNAPTAAAKYKFYQEIKCYVNDLVDCLSEKAPVIYDLEKRALQQYGKNQRYLVNRRRQDVRDQAKEIAESAKPITAASRRTPDYEEQVRRAAEREGRRTRRRCERERNDLLSSHLDGMSSDDEIADQQQELSVTTMAQIESQSVDALEDVTDDFSKIELILMKFFAWRKTDMSSYQDAFVSLCLPKVLAPLVRHELVLWSPLLDVYADIENMRWYQACMLYASQADETVEQLKIDPDINLVPALIEKIVLPKVTALVTECWDPLSTTQTLRLVGFINRLGREFPL--SGTNKQLNKLFESIMERMRLALENDVFIPIFPKQVQEAKTS----FFQRQFCSGLKLFRNFLSWQGILADKLLRELAIGALLNRYLLLAMRVCTPN-DAINKAYIIVNTLPTVWLLPNSE--TLKNMELFIGYIKQTLENCDASNPIFMQSSDKAKQILQRLHSL----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*:: *: ..:*.: . . . : . . : . : . .. . :. . : .:. : .. * . .: **** *:**:.:*. ** ***.:: : . :* :.: .*.*.*: : . ... .: *: :.:.:.. : **:**: *.* . . : .: : . : . . * : :* *:: : . : ::: * :: :. : :**: :: : :::::**.** * .:* .. ::.:*:: :: ::. : : : : : : . . .. ..* * . : . . : .. ..: :* ::* .:: ** :* ** . .** :*::.:*:**:* **:* :*: *.** .:. : *: : : : : . * . :.::*:* ::.:: :* *****: ** * . .:.. .* : :.::: *:: ::::*:*:*::**. * * * * ::** ..:**: *: * *::.:. *::* : **.***:::: ..::*. :. :* *: :: ::: * .: *: . . :* ::: ", "identical_positions": 108, "similar_positions": 255, "identity": "11.5%" }, { "cls_id": "homologset.agr.MGI:2141658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R1C3-1", "uniprot_id": "VOPP1_MOUSE", "id": "Q8R1C3-1", "name": "WW domain binding protein VOPP1", "aln": "MGRRLGRVAALLLGLLVECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPTFNVSYTRQPPNPAPGAQQMGPPYYTDPGGPGMNPVGNTMAMAFQVQPNSPHGGTTYPPPPSYCNTPPPPYEQVVKDK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEK8-1", "uniprot_id": "VOPP1_RAT", "id": "B5DEK8-1", "name": "WW domain binding protein VOPP1", "aln": "MARPLGRVAALLLGLLMECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPTFNVSYTRQPPNPAPGAQQMGPPYYTDPGGPGMNPVGNTMAMAFQVQPNSPHGGTTYPPPPSYCNTPPPPYEQVVKDK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96AW1-1", "uniprot_id": "VOPP1_HUMAN", "id": "Q96AW1-1", "name": "WW domain binding protein VOPP1", "aln": "MRRQPAKVAALLLGLLLECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPAFNVSYTRQPPNPGPGAQQPGPPYYTDPGGPGMNPVGNSMAMAFQVPPNSPQGSVACPPPPAYCNTPPPPYEQVVKAK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F4X8-1", "uniprot_id": "E7F4X8_DANRE", "id": "E7F4X8-1", "name": "WW domain binding protein VOPP1", "aln": "MRS--GGAAAVLLLTLLECVEAKKYCWYSEGGYPLFFICRSYEDCCGTRCCIRALSIQRLWYFWLLLMMGVFFCCSAGFFIRRRMYPSVLSDEPAFNVSFTRQPVS-TPVSQQ---PVMQGFGEPCVG-MGASLTPVYSGQSPAAAMMSSYPPPPSYCNHPPPAYDQLFSSAEKKSRSESPQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NG32-1", "uniprot_id": "A0A8M1NG32_DANRE", "id": "A0A8M1NG32-1", "name": "WW domain binding protein VOPP1", "aln": "MRQICGLLITLLF---AETVAEKKYCWYFEGDYPVYFICKAYEDCCGTECCVRALAVQRIWYFWLLLIIAILCCCSTGYFIRRRAHPYPPSDRPEFTVAFSRNPII-TPGLRQ-----------TGFHSYGDSETAVISTVFPAVSALSYYSQGP-HPHHPPPSYEQVMQDSQKK-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ::*: * . **:*** ** ** ::**::******:.**:***::**:****:**::.:: **.:*:***** :* :.* *.*:::*:* * :* . . * : : . . : . * : : ***.*:*:.. ", "identical_positions": 56, "similar_positions": 49, "identity": "30.77%" }, { "cls_id": "homologset.agr.MGI:2141669", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NDL0-1", "uniprot_id": "EOGT_RAT", "id": "Q5NDL0-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLMLLVFGVLLHEVPLSGQDEAHPEADRVPGEALYDYSSLRLPEEHIPFFLHSNRHVASVCREDSHCPYKKHLESLNSCWGYEKSCTPESRFGSPICSYVDLGWTDTLESAQDMFWKQADFGYARERLEEIRMFCRPESASDSSLLCSRYLQYCRATGLYLDLRNIKRNHD--RFKEDFLQGGDIGGYCKLDRHALVSEGQRK-SPLQSWFAELQGYTQLNFRPIEDAKCDIVVEKPTYFMKLDAGINMYHHFCDFLNLYLTQHINN----SFSTDVYIVMWDTSSYGYGDLFSDTWKAFTDYDVIHLKTYDSKKVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFSQHVLHRLNISQEGPKDGKLRVTILARSTEYRKILNQNELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGIYYITWQKPSKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAAEHVLQHPQWP-------LKKNHDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYW9-1", "uniprot_id": "EOGT_MOUSE", "id": "Q8BYW9-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLMLLVFGVLLHEVPLSGQDKAHSEADDAPGKALYDYSSLRLPAEHIPFFLHNNRHVASVCREDSHCPYKKHLENLNYCWGYEKSCAPEFRFGSPVCSYVDLGWTDTLESAQDMFWRQADFGYARERLGEIRTICQPERASDSSLVCSRYLQYCRATGLYLDLRNIKRNHD--RFKEDFLQGGEIGGYCKLDSHALVSEGQRK-SPLQSWFAELQGYTQLNFRPIEDAKCDIVVEKPTYFMKLDAGINMYHHFCDFLNLYLTQHVNN----SFSTDVYIVMWDTSTYGYGDLFSDTWKAFTDYDVIHLKTYDSKKVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFSQHVLHRLNITQEGPKDGKVRVTILARSTEYRKILNQDELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGIHYITWRKPSKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAAEHVLQHPQWP-------FKKKHDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5NDL2-1", "uniprot_id": "EOGT_HUMAN", "id": "Q5NDL2-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLKYCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIKRNHD--RFKEDFFQSGEIGGHCKLDIRTLTSEGQRK-SPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLYITQHVNN----SFSTDVYIVMWDTSSYGYGDLFSDTWNAFTDYDVIHLKTYDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFAQHVLHRLNITQEGPKDGKIRVTILARSTEYRKILNQNELVNALKTVSTFEVQIVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGVHYITWRRQNKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAADHVLQHPKWP-------FKKKHDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2Q0-1", "uniprot_id": "A0A8M2B2Q0_DANRE", "id": "A0A8M2B2Q0-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLLLVALCLLCNNKTVSATDSSR--------TPQLDYNSLALPQRHIPFFLHNNKPLAKLCKEDPLCPFKDALLLRKACWGYEKSCSAEHRFSYPVCTSLDSGWANSIQAAQELFWKQADFGYVRERLNEMKTLCKPSKPADSSLKCSSHMRFCRATNLYLDLRSPRRGHE--RYKEDFLEQGEIGGHCSLNSKALEAEGTHK-SPLQSWFSELQTYSELDFHPLDDGHCDVIIDRPTVFMKLDAGVNMYHHFCDFVNLYISQHLNN----SFSRDINIVMWDTSVYGYGDLFSETWRAFTDYDIIHLKNLDSKRVCFRDAFFSLLPRMRYGLFYNTPLISDCHSEGLFRAFSQHVLHRLSVPQDGPKQGQVRVTLLARSTEYRRIINQQELINALKTVPLFEVKLVDYKYKEMPFLEQIHVTHNSDIFIGMHGAGLTHLLFLPDWAVIFELYNCQDESCYRDLARLRGVQYMTWQKRDKVFPQDKGHHPTLGEHPKFTNYTFDVEEFMRLVLLAAEHVTRHPDWR-------AKQSREEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQB7-1", "uniprot_id": "EOGT_DROME", "id": "Q9VQB7-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "---MPILPILIGILHLSLAEDAK---------HLDGFSLPSLPSEHLIRYLNTFPKLKQQLPTN----LTGKGTISSACWGHERDCTPAGRFQTPQCPGEHTGWARSKEAQVRTFYNQADFGYIQEQLSQLTPQCVPTYLGDSSLECTHYLRFCRGRNLLFDFRGLEQREERIRYHMDVLGPGQLLGHCKLNRTRLSGEMEHIGSALQSWGPELRNFDVLPHPVLESGLCDVVVNTPTFIMKIDATYNMYHHFCDFFNLYASLFVNQSHPAAFNTDVQILIWET--YPYDSPFRDTFKAFSQRPVWTLSDVEGKRVCFKNVVLPLLPRMIFGLFYNTPIIQGCSNSGLFRAFSEFILHRLQIPYKPPQQ-KIRITYLSRRTKYRQVLNEDELLAPLEANDKYDVQRVSYER--LPFTNQLAITRNTDILIGMHGAGLTHLLFLPNWACIFELYNCEDPNCYKDLARLRGVRYRTWEQRDLVYPQDEGHHPEGGAHAKFTNYSFDVKEFVHLVDGAAEEILSHKEFPRRASENPSKTQRNEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :* :* :.: .: ** .*: :*:. : : . . ***:*:.* . ** * *. . **: : :: *:.****** :*:* :: * * .**** *: ::::**. .* :*:*. .: .: *:: *.: *:: *:*.*: * .* : *.**** .**: : * . ::.. **:::: ** :**:** *********.*** : .:*: :*. *: *::*:* * *.. * :*:.**:: : *. :.*:***::..:.***** :*******:*..* . ******::.:****.:. . *:: ::*:* *:* *:**:::*::**: .*:: ::*: *.*: : * :*: :*:*:**:***************:** :******:* ** *******: * **.: . *:***:**** * *.*****:***:**: ** **:.: * .: * .::**", "identical_positions": 200, "similar_positions": 166, "identity": "36.97%" }, { "cls_id": "homologset.agr.MGI:2141676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N1E6-1", "uniprot_id": "FXL14_HUMAN", "id": "Q8N1E6-1", "name": "F-box/LRR-repeat protein 14", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------METHISCLFPELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLK---VLNLGLWQMTDSEKEARGDFSPLFTVRTRGSSRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BID8-1", "uniprot_id": "FXL14_MOUSE", "id": "Q8BID8-1", "name": "F-box/LRR-repeat protein 14", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------METHISCLFPELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLK---VLNLGLWQMTDSEK-----------VR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L9R6-1", "uniprot_id": "A0ABK0L9R6_RAT", "id": "A0ABK0L9R6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------METHISCLFPELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLKSPPQQHERPWRNPETFIN-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4KF28-1", "uniprot_id": "A0A0B4KF28_DROME", "id": "A0A0B4KF28-1", "name": "", "aln": "MATNTELLPFHHQTIAVLNNLNSHCGGSGSNGAATSGGAAIGGAGAGGAPSWAMDELYQQTELPGLTRTGATTTHHHLLRFTPYALHHRPPHHQLQTLPPALYLQHAAAAAAAAAAAAAHAQHHHHHHHHLPHRPASPESPPPVEGTHISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIKKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLARMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPKLQ---KLNLGLWLVRXCVHHDCNACAAKEAARGSYNSQP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** ****** ** :* *** *************** ****:********:*:.**** .* ***::**********. :: *:. : *******:*::* .***** :: .*::*:*********:*******:*:.**.******.**************::** ****** *:** *******::*.:*** * ** * *****:*:* :* **::***.*: :***** .::*:** **::* .*..*********** *: :*: *. :..********:.**:*::***** *:**** .*:*:*.*: ::.: :* *..****** *******: :**.*::*. *******:::.:*:: * :** *: : * ", "identical_positions": 241, "similar_positions": 95, "identity": "42.65%" }, { "cls_id": "homologset.agr.MGI:2141677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9R4-1", "uniprot_id": "PRRT4_RAT", "id": "D4A9R4-1", "name": "Proline-rich transmembrane protein 4", "aln": "----------------------------------------------------------------------------MAGRGCLELGLFCWVLLAVPVGPQPASSVPGAPLTTLTPPPQSEASMLSLNLGLNFKFHLRG---PAAVWGSPVTETHPLSPGLGQESEEDLEGDLRTDPLWELLVGSPGNYVPEWGSAEGSFTPWASSLPPESTSPLSGPTKRPTAPSQPRMSTVTWATALTATAPPTSAPRPRQSELELKFDVALRAGAAPTLGHRSLPLLPSLRASLAEIAGRLGPFGFFGTTLSPLRNFSSQSYQGTTAQPSFASEVSDFPGLFGTTGSLPPPLLERKFSSPSPLDSVASPSSASIKTTPVQHDPTVSTSDPDELSP-ASFGSPSAQPGCEPGSCSEPELSDDSGQPPASPLPLFFLTLEADWAEARARWGLAWEAHVYGAGALFGLVALLALLSLALLPWRCPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLP-ALAWLLLQDLPLPCLAAGLGLACLLLARP---------RTPRCPIGLAALLLLGLGLAAAAALGSAVHR-PLRPLRLASRGLHAFLAAFLSGLLLALSCWGGRRRRAGAPLGGSGFKGATPVPQVRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGG-QTGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPRR--CWAKLFRLSPG-----HAAPLLPG--GWVPGIRDKEPLGSAIARGDAELLQLCALAGP------GPDLLLQGGSCPGFEGARANT--------TQSPASSPSSDCTVDFRPPSPINLRRSIEEALCSEALLAPGLFQGPAFGDALSG-LGLYRTISLGNKTGAGPSEKSEKVPGSPAPPELPSPGAWPPGSSASSGSLCGLSRDSSSMLLCSSPDRPPRCP-----------------LVCVLSPPRPSESSPSLPASGSYQALSPPSRD----------SPEHASELQAEEALLQEQFLDACRQIDELSMGSDTIDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RU40-1", "uniprot_id": "PRRT4_MOUSE", "id": "B2RU40-1", "name": "Proline-rich transmembrane protein 4", "aln": "----------------------------------------------------------------------------MAGRSCLELGLFCWVLLAVPVGPQPASSVPGAPLTTLTPPPQSEASMLSLNLGLNFKFHLRG---PAAVWGNPVTETHPLSPGLGQESEEEEEGDLRTDPLWELLVGSPGNYLPEWGSAEGSFTPWASSLPPESTSRLSGPTKRPTAHSQPRMGTVTWATALTATAPPTSAPRPHQSELELKFDVALRAGAAPTLGHRSLPLLPSLRASLAEIAGRLGPFGFFGTTVSPLRNFSRQSYPGTTAHPSFAFEVSDSPGLFGTTGSRPPPLLERKFSSPSLLDSVASPSSASVKTTPVQQDPTVSTSGPDELSP-ASFGNPSTQPGCEPGSCSEPELLDDLGQPPASPLPLFFLTLEADWAEARARWGLAWEAHVYGAGALFGLVALLALLALALLPWRCPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLP-TLVWLLLQDLPLPCLAAGLGLACLLLARP---------RTPRCPAGLAALLLLGLGLAAAAALGSAVHR-PLRPLRLASRGLHAFLAAFLSGLLLALSCWGGRRRRAGAPLGGAGFKGATPVPQVRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGS-QAGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPRR--CWAKLFRLSPG-----HAAPLLPG--GWVPGIPDKEPLGSAIARGDAELLQLCALAGP------GPDLLLQGGGCRGFEGAGANP--------TQSTASSPSSDCTVDFRPPSPINLRRSIEEALCSEALLAPGLFQGPAFGEALPG-LGLYRTISLGNKIGAGPSEKSENVPGSPAPPELPSPGAWPPGSSASSGSLCGLSRDSSSMLLCSSPDRPPRCP-----------------LVCVLSPPRPSESSPSLPASGSYQALSPPSRD----------SPEHASELQAEEALLQEQFLDACRQIDELSMGSDTIDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C9JH25-1", "uniprot_id": "PRRT4_HUMAN", "id": "C9JH25-1", "name": "Proline-rich transmembrane protein 4", "aln": "----------------------------------------------------------------------------MARHGCLGLGLFCCVLFAATVGPQPTPSIPGAPATTLTPVPQSEASMLSLNLGLNFKFHLRG---PAAVWGSPVTETQPLSLGPGQEPGEEVASGLRTDPLWELLVGSSGNSLTEWGSTEGGSKPRASSLLPESTSRRSGPSDGPTAPYQPRRSTVTWDTALMVTALPSSAPRPHQSELELKFDMALRAGAAPTLGHRTLPLLPSLRASLAEIAGRLGPFGFFGTTLSPLRNFSGLSPPGETTSTSSASGVSGSLGFLGTTLSLPPYSLERKLSSPSPLDPAASLSFASIATT--SLDPTVPISGPDDLSPPASLGNPSGQPECGPGSCSVGELPEREGQPPEAPRPLFFLTLEADWAEARARWGLAWEAHVYGVGALFGLVALLALLALALLPWRCPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLP-ALAWLLLQDLPLPCLAAGLGLACLLLARP---------RPPRCPTGLAALLLLGLGLAAAAALGSAAHR-PLRPLRLASRGLHAFLAAFLSGLLLALSCWGGRRRRAGAPLGGSGFKGATPLPQGRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGG-QSGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPPR--CWAKLFRLSPG-----HAAPLLPG--GWVTGPPDKEPLGSAIARGDAELLQLCALAGP------GPDLLLQGGGCRGFEGAAANP--------APSPASSPCSDYTVDFRPPSPINLRRSIEEALCSEALLAPGLFQGPAFEDALPG-LGLYRTASLG--TGGRASERSGEASGPAAPPELPSPGAWPAGSSVSSGSFCGLSRDSSSMLLCSSPDRPPRCP-----------------LVCVLSPPRPSGSSPSLPASGSYQALSPPSRD----------SPEPASELQAEEALLQEQFLDACRQIDELSVGSDTIDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IBE2-1", "uniprot_id": "A0A0R4IBE2_DANRE", "id": "A0A0R4IBE2-1", "name": "", "aln": "MLLLYRTLVVFSLFSSVNGFFGGNGPKPTAQTKADSKGWGLPYLPNWKPPSLGLGSFNFFNRNRDSAGTKVSLTLPEATTQDYILSSEDLTTLKYQPTATTNEELQSSTVQIGTLLPLKSAKLPTDHLLRNKPQLQSSDPPPSILDHSYDLDLWPPNIGQSTSKTPQTTSPQITRPQTYTLSTAQSTSITQNGTLSMVTETMNS------YTDQIEPTDTPSTTSELTETSFQTTHFVTPADPKPEVSTDHLTTVSTGQNTLETTNTASKPEWTTFEPTEKTLDGFTWVEQTTSPTEMGKFRESFGTDSTAALPAGGFAWEEGDKDTAKNADLTTQKRHDELTTSASFTTLRNTEMPSTVSEDWLTDFTQESALPDCNAERSGICSS-SDTWPTTVLSNSSKNDSTTTVSTNLSQSPILFPAPPMFVALYSDWNSALATWGSAWEAHIYGLGTVFCLVALASTLNLLCLPLQYPSGCGYFALVSFCLVAAGSTRAFALVYDAYGYQDRMSSTEASLLLYEAPFPCMTAAFGLVFLLLSMRSRMQLS--YSVFQRPCILAGLVLLHFAAAFGPVALLHVDQRVYLFLSLISRGAFVALATFLSAAYFVFYCYVRADSKHIYHLNNTSP--TPAERYNRCPFAESRDWDRAAAAVLLSAIFSLACAGLQLYAMLHALGMAGSVES-FRPWPWWTFQFSCRVCEAVVCLTLVLVVAQPVYCSDHLPQAGSCWTELLA---------AKSPIIPGSYQWTLSHQEKLAICDPIGHGETECLPLYTLVDDRLGSLNGLDLLYHSNRALAYRDLDLDLPNTHPNTGAPSMGSSCTSDSTADLRPPSPINLRRSIDEALFSESLFPMSIFSPLRPFTSSDRSLNGRETISSGAQTARGTLIPDPGLYRTSSCVEVLPQAPIPPQAQMNGPSLGFPPSPSPSLSSSTCCSSPERWRGSSSSSSLYRQSLGGSSLVLCSTPEGHHPPSSTLSGGSSHTASSGHQRDNVQRPYRTLKSEDSLDQQSEFDQSVQEEFISVCRQIDALSICSETIDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PYT1-1", "uniprot_id": "A0A8M9PYT1_DANRE", "id": "A0A8M9PYT1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------MTPHRQALLLLFTLSQCASLSLNRNEQAHFLPSTDPEPGKSSS------WTAKMDPSLSPDVHPNRDLLTEPNLYITTASKTQWIKTVVSSKTELPSDIQ------NDEEGTQTEQSDWTNFKQDRSFKTSLATLQPFPSQTSESKYRNTFKS-KTAAETSTHRTLKKSFSATQTPYVRGTLDGTTSPKDPSEKTKNLTDAPTETTFIMTS-----PERDREEHEGVEHVKKEKKGQSTSIVIKVTETSPKTASPG-----DDWSRSATLPDCNLVGFGICQS-SDASINNTLSTPPP--VYLTTPPGVINPPLEDLTPPLLVPLLTDWNAAMATWGLAWELQVYVLGCVFMLVAALSALSLMCLPLRWPSGCAHFSLLHLLQLLTSSSRALWLLYDPYGQKERLP-IGWARLLHEAAYPCLTASFGLLLLLLTARSCTQLLSQNTLQRSTCLLAALVLLHVAIVMASMAILQLFP-TLQVVPLLPAAAFVLMSSILSFTYLLLYCCARADVKHIYRLNESSPE-RPSCHASRCPFTEARMWERAAKAGVFSALFLLACGSLRLYAMLLAGGLTGGVMVGLMPWPWWGFQLSCRVCETGVCLTLALIITHPLLCCGVPPSKPGGCSWLFKNQTTEGTTSGKPTILSSRCGWSLRPAEKLGLCEGIVRRESESVPLYTLVELPHSESDGLDLHYPSS-PQHKPSTQLAQPTKTNKASQASSFASLDADSTADLRPPSPIDLRRSIDEALNSEALFQHSLFGSSRLSLSTRGPPDGQPCRGNSTEVS---------LYRTSSCGDVDPAT-----------------VPSRSRQWSTISGRPAQVS------------------VHCGGINSTEHSQSSLHRG-SHSGQQLHRRYTTLGSTSSRGSVDVDATSHVDELAVQAEFINVCRQIDALSISSDTIDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ... : : : *. . . . . . . * * : : : . . . :. . :. . . .. : . : : .* . : : . : . . . : * . .. :. . . * * :::.* :** * * ** *** ::* * :* *** : * * ** : *.*. ::*: : : :.::**: *.**.** ::*:. ** : . **::*.:** ***: : . **.*:** .. . .. : * . . .. ::::** : : * : *. :. .. *.**: . * *** : .:. * * ...*: * :* * * . ***** **:. *: *. *.*.*.*: * *. * : *: ..::.. * :* : . * : ::* : * :*. * ** .. . * :* :* *.*:******:*****:*** **:*: .:* : . . . . ..: :: . * * .: . * : * ...:* . *: . . * * : : :* :*:..***** **: *:****", "identical_positions": 143, "similar_positions": 196, "identity": "13.68%" }, { "cls_id": "homologset.agr.MGI:2141787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NWW7-1", "uniprot_id": "CB042_HUMAN", "id": "Q9NWW7-1", "name": "Uncharacterized protein C2orf42", "aln": "---------------------------MEPNSL-RTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFR-----YGARKQPSVEAVKIIT-----GSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVEN------------QCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTG----PLVQRITKNILVVKCKASQKHSLGYLHTSF-VQKVSGK---------------------------------------------------SLPERRFFCSCQTLKSHKSNASKD--------------------------------------------ETAQRCIHFFACICAFASDETLAQEFSDFLN----------------------FDSSGLKEIIVPQLGCHSESTVSACESTASKSKKRRKDEVSGAQMNS--SLLPQDAVSS----NLRKSGLKKPVVASSLKRQACGQLLDEAQVTLSFQDWLASVTERIHQTMH------YQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFVRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAET--YGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R3C1-1", "uniprot_id": "CB042_MOUSE", "id": "Q8R3C1-1", "name": "Uncharacterized protein C2orf42 homolog", "aln": "---------------------------MEPNSQ-RTKVPAFLSDLGKATLRGIRKCPRCGTFNGTRGLSCKNKTCGTIFR-----YGARKQPSIEAVKIIT-----GSDLQVYSVRQRDRGPDYRCFVELGVSETAIQTVDGTIITQLSSGRCYVPSCLKAATQGIVEN------------QCQHIKLAVTCQAEATPLTLKSSVLNALQAAPETKQSLWQLATEPTG----PLVQRVTKNIMVVKCKASQKHNLGYLHASF-MQKISSR---------------------------------------------------SLPERRFFCSCQTLRPHKSSVPKA--------------------------------------------EAAPKCIHFFACLCAFASDETLAQEFSDFLN----------------------FDASGLKEIIVPHLGCHAESSVSACESAASKPRKRKKDEVSGAQVNS--SLMPQDAVNS----NLRKSGLKRPVVTSSLKRHVCGQLLDEAQVTLSFQDWLASVTERIHQTMH------YQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFVRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVENIAES--YGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVADYQDPRPPMDQPLELAPLTTITFP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q8U1-1", "uniprot_id": "A0A8M9Q8U1_DANRE", "id": "A0A8M9Q8U1-1", "name": "", "aln": "MDGPLVNSGIPLETQTVVSPVPQTSTNLTANPRDKRRTPAFLSNLGKATLRGIRKCPQCGYYNGTRGLSCKNKACGTVFRDVDHRTGHSKKGASEVVQVVTDSGGRGGGLQVFSVRQRGRGSEQRGFVALALTDTAITTADGTVLTRVNVGRCYMPSCQQNESDSTVDLGVNQQESQPSKSPCTHVKQAMECQIQATPLPLKSSVLEALVASSQAKAELWRLATETPG----PLVQRVSKGTLIVKCQPGEAHPLGLLHLTVGVFGFKEK---------------------------------------------------TEGAAPFRCACYAANVKGDLVTRSG------------------------------NQSNVQGENSHGHSLPECCLHFFACVCAFRSDEKLTSEFSAFLN----------------------YNMNGIQQSADSIVLAISESQQHSESFISHRPKRHKFVESSTASSVSSASLLAVKDTSAPT-VNQRKPTHRKHSSSSGLKNPGSSQPVDEMHVSLSFQKWLSSVTERIHQTMH------FQFDGKPEPLVFHIPQAFFNALQQRLSLGSKKRRLPNYTTTFVRNDALPLGSFSKYTWHITNLMHVKRIFDTPELPLELTRSFVKNSDGSYSLYRCRETPLDPGSDTSHHSRINKPLAIRPLELRTFLRVGTCSAEQTEPVPFVIEWIPDILPHSQVGELRIRFEYGHQLGSKPEHCKSSAGKERTEQTIADAITQQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAL2-1", "uniprot_id": "Q9VAL2_DROME", "id": "Q9VAL2-1", "name": "Treble-clef zinc-finger domain-containing protein", "aln": "-------------------------------------------------MRGVRKCVHCGAINGNRALLCKNSECP------------QRRNVLDAVQLVS----LRPGSTVYSLRTKEKEQQPRNFVVIQDVTLSLQPDAAVVS---SKAECFVESCKRTGGEPTDCV------------HVKACRELGAEFAKAQVYRVSREVLWNLNISLEQKQNLWQLYKYAEEEEHLPGVQRLNHSTFAVKCERSESFPAARLHVTVSANGLSKKKSSYACACRKLKIIVEPDNSLVMQDEICDHLLLVLAGILSSPQGKRVYGHFTSGLQTFWMPLQLETPLGDVATEDLRLSLDMVDELDPQVDILVFGDQLDLSLPNLSDGVFNLDTMQAATSSQSASSTNDALIHYANDSQLLSNLDVYAEPIELTDCNIELMDQFQPTDQLDICSEDIELPLISEPYNILAAPPIFTEATPSVVADQLPIELATISMVKKAPVKFSEIVTEVKSLKQPSLPAKRELIVNGAASAASACLDASVQPALSYSAWLDHVIELLNDSCEPLETESNTLTKRLVQQNFHVHKETFSHFCKSFSTGVKRRPLDKLTVIESGKHKG----LSKYTWHFASPHTAKRIFSTSNVQLQLDRAFERHAEGHFVPYVRPPMEPQVPGQP------KKRIVYPRLSLYMVKILFEAAPKDYVGNGVLVTWTPDVLPRSQFGLMHVEFTVETRPPR---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:*** :** **.*.* ***. * :: :.*:::: . *:*:* : : : * ** : :: . ..: . ..*:: ** : : : :* :. .** : : : * :*:* . . * ***:.:. : ***: .: . . ** :. .. : : * . . ... . . .: : .*. * .::. : : ..:: . : . . : * : . . .: . .. : . :: .. .. . : :**:. ** * * :::: . : : **: : *. : : :* * :: * : *. :. :******::. .*:*:.*.:: *:: *:* :: :* : : : .:. :* . *.* . : :..: .:: * **:**:*:.* :::.* : ", "identical_positions": 81, "similar_positions": 173, "identity": "10.66%" }, { "cls_id": "homologset.agr.MGI:2141794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUV5-1", "uniprot_id": "A0A8I5ZUV5_RAT", "id": "A0A8I5ZUV5-1", "name": "", "aln": "------------MASVFMCGVEDLLFSG---SRFVWNLTVSTLRRWYTE------------RLRACH-------------QMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPAVLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRVSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDDPNDSFTLAGQRPSSVPHSPRILPPKSLG----------IERIHFRKSSINEQFVDTRQS------REMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAAGPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDTLRNGVYSKGQDPPPSGYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYQSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAVKSEHITKNIHKAIVAEHLRGWYQRASGQKDQG-HSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTN-ASGNWRTQLTTGLSEYENPVHSPYTSYYGNIYNPLPSPNRQYAEST-------------PLDGTDGNQLEDSLESSEQRLFWHEDSKPGTLV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920B0-1", "uniprot_id": "FRM4B_MOUSE", "id": "Q920B0-1", "name": "FERM domain-containing protein 4B", "aln": "------------MASVFMCGVEDLLFSG---SRFVWNLTVSTLRRWYTE------------RLRACHQVLRTWCGLRDVYQMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPTLLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRGSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLQKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDDPNDSFTLAGQRPSSVPHSPRILPPKSLG----------IERIHFRKSSINEQFMDTRHS------REMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAASPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDPLRNGVYSKGQDPPPSGYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYRSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAVKSEHITKNIHKALVAEHLRGWYQRASGQKDQG-HSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTN-ASGNWRTQLTIGLSEYENPVHSPYTSYYGSIYNPLSSPSRQYAETT-------------PLDGTDGSQLEDNLEGSEQRLFWHEDSKPGTLV---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2L6-1", "uniprot_id": "FRM4B_HUMAN", "id": "Q9Y2L6-1", "name": "FERM domain-containing protein 4B", "aln": "------------MASVFMCGVEDLLFSG---SRFVWNLTVSTLRRWYTE------------RLRACHQVLRTWCGLQDVYQMTEGRHCQVHLLDDRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIFKLAAFILQEAKGDYTSDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLP-EDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLG----------IERIHFRKSSINEQFVDTRQS------REMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQG-HSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTN-ASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLPSPSRQYTEIS-------------QLDGTDGNQLEDNLESSEQRLFWHEDSKPGTLV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN59-1", "uniprot_id": "A0A8M9PN59_DANRE", "id": "A0A8M9PN59-1", "name": "", "aln": "------------MALGLFCCMEDLLAAG---SQLVWTVAEQVLRRCYSDGLVP------------CRRFLQTWCLLGDVYQMTEGRLCQVLLLDDRQLELLVQPKLLSRDLLDLVSSHFNLKEKDYFGISFTDERGQKKWLQLDRRVLDHDFNKKSGPLELKFQVRFYIESVAYLKDATTVELFFRNAKISVYNENIEVESEIVFKLAAYTLQEANGDYTSDESTRSALKKLPAFPTAVLKEHPSLTFCEDKVIERYKKLKGLSRGQAIVRYLTLVESLPAYGVHYYKVKDKQGLPWWLGISYKGIGQYDLQDKLKPRKLFLWKQLENLYFREKKFAVEVNDPQRRTASRRTFGQSGQAIHTWYASHSLIKTIWVMAISQHQFYLDRKQSKAKITTARSLGDIAMDLTETGAPRNSKLVSMESKDKLIMASNGSLVSSNSADNDVNEEQKKEKIAELKDKQEKIKQILALKEEELKKMCLREAELTGVLPKEFPLASGEKPPTIRRRVGTAFKLDD-LFPYDADPCLRNLESCFALQKKIVEAARKLAHENELGKTVKKKRRRNLLDATKKLQAIENEINDYRVKIGKEPTQRASVIIADDVN---LDSLSDCLNLDDDEPSQ---RQRSRSVQYSPLPNSSGSFTASYHSDQLDHANDDYSNCSRLN--YAEVQEP-VAYIHEDALSTHSSPYRQPLRQPSDSRSMPPTPQLPRNAYSSIQLST-----LYRQRSGSLESQSQFLTESEPSEPVFISAP-RRSNSTELLDDGSSYTSQSSVEYSAP-------------HSRAKNRHRRRQGNIYA-NTGSMPNLAQNDTRGYISQSQHPQT-TTAYYVTGYPRYIEPEVYPNGPYMYESEMEGHYNVNPSYHRHEPHG---------NYAQDEMDGLSHNLYATLRPPRNRPPSRNDNLVKNMQRAEVVEHLRGWYNR--QHKPQG-------YDAYRAPQQSLNYRTMSTSYVRSDSTASYSTVGS-----GNWHGQPVMAMSEYEMPLAHHQSYGYNTVHHSHPLHSSSHPKRAWHCPASPQYYHPRFSQACSSSLPPRPLPPSSSCYQMKQTGLSAPQTGGARVNKASFAKCSP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AV01-1", "uniprot_id": "A0A8M3AV01_DANRE", "id": "A0A8M3AV01-1", "name": "", "aln": "MKEQRSGSAERVICVCVCVCSVTRLCNPGVRAAMVWGLVCVCVCVFRAAGFIWRLVFWAVGRMRCCQESVQTCFYLRHVYQMTEGRLCQVQLLDDRKLEMLVQPKLLSRELLDLVSSHFNLKEKEYFGFTYVDDTGQCKWLQLERRVLEHDFSKKSGPIALQFLVRFYIESISLLKEHTTVELFFLNAKSAIYNGDIEVESELVFKLAAHALQESKGDYTSDENTRADLKKFPVLPTKVLKEHPSLAYCEERVMEQYRLLKGISRGQAIVQYMTLVQSLPTYGVHYYEVKDKQGMPWWLGISYKGIGQYDHQDKVKPRKLFQWKQLENLYFREKKFAVEVNDPHRRAVTKRTFGQTGLVIHTWYATHSLIKTIWVMAISQHQFYLNRKQSKAKITTARSLGDIAVDLTENGASKMSKLSAG-VKNQLIMASNGSLVSTGSADSEMNDEQKKEKLAELRKKERDIQDILSQKLTELKEICLREAELTGKLPKEYPLIKGETPPHVRRRVGTAFKLDD-LFPYNEDPYLRNLESRFALQQKIVEAAKKLAAEPDISKLVRKKRRRNCLDAMQKLQEIEDEMNQYRLKKGQKPTQRASVIIADELAQSECSSLCDSLPLDDDDGGQ---RPRSRSVQCSPCLSPPLSSSGLDFDPERRSSSSDTHHDRPLNRLDHEVQEPGHYYTPREVFSAQSSPCKTLSRMPKDPRSLPQTPVLPRNAYSSSQLRSDGHIRAFRHRSGSLESQSQLFHSHCANKSVFPLSPSRRSNSTEVLDDCSSYTSMSSMDFCLPCSATPPY---RTLDSHSHDYRLHRKVEIYG-NTGSMPNLVPQNSS---SYQQNHYG-PTAYYVAGYAG-FDYEPCSNGAYVYESEIEGHYNINPTYPAHGYQGRGR----NRHYGIEGLDNLSQNPYATVRPPRGRQGPLNEVLTKNMYRALVAEHLKGWYNRSAGHRDPGTYQLVYTYKYDRGSQHSLGYQTLPAPFSHSSRTNSFSSVSSTASGGGNWQNQLAVGLADGELPDGPLSAGAYSPAYSRSPTHSSRFPS---------------EGAASHTSEPLEVFGAVASCSDTEN-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * : :** :. : : *: ****** *** *****:**:*******:*:*****:********:***::: *: ** :****::***:**: **.** *:* *******:: **: .****** *** .::: :***:** :***** ***::*******.:* **.:*.:** .*:*****::**::*:*:* :**::****:*:*:.:*::**:****** ******:*************** ***:****** ******************:**:* :.::*****:* ::****. ****:*************:********.:****.:**:****.*: : *** : *.::********:*:.* *.: :***:**: **:.*:. ::: * * ***::********* :***:** **.** :******:***** *:* : ** *::*** * :*:*:****:*** * :: * *:***::: ** ::** **: :*:**:: *::*:*:*:*: ::: .**.* ** . . *. ** ** .. * . . :* :.:.. .: :*::*** : * *.. **:* ** *.****** :* . *:*********::: . ..:..* : :**.***:*** ***** ** :: .::::. : :: .: *:******. ::. .: .:.**::**. : : .* *:**.: **:*.:**:* * : : :* :.:* ***:* ** : .: :.**: :* *.***:***:* :: * :. *..*:.*.: : .. *. : *:*:*.* ***: * . .::: * * : *. : . . ... . . : . .: ", "identical_positions": 440, "similar_positions": 275, "identity": "39.68%" }, { "cls_id": "homologset.agr.MGI:2141810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADA7-1", "uniprot_id": "D4ADA7_RAT", "id": "D4ADA7-1", "name": "", "aln": "VG-AETMESSSLLLCKGLLLTASLLTFWDSPAAALLTTKEMRFSAAEGAKVLLHVPDQEEDLVSFSWYKGKDVNENLTIAHYEKSSDSLQIGKKVSGREEIYKDSSMMLWAITQKDTGFYTLQTFKAHDQQEITYVHLQVYKIVTKPYLKLNHTRVKRKSASIFTCVSPDTGVDISWFFNYKPLNVTERVTLSAENRRLTISPVWKADAGIYQCEVSNSFSSKKTNPLLMVLAYG----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4J1L0-1", "uniprot_id": "CEA15_MOUSE", "id": "A0A0B4J1L0-1", "name": "Cell adhesion molecule CEACAM15", "aln": "MG-AETMESPSLFLCKGLLLTASLLICWNWSTAALLTSKEMRFSAAEGAKVLLSVPDQEENLLSFSWYKGKDVNENFTIAHYKKSSDSLQLGKKVSGREEIYKDGSMMLRAITLEDTGFYTLQTFKAHGQQEVTHVHLQVYKIVTKPYLQLNHTRLKRKSASILTCVSPDTGVDINWFFNYKPLNATERITLSPEKRELTISPVWRADVGIYLCEVSNSFSSKKSYPLLMALAYG----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KPI0-1", "uniprot_id": "CEA21_HUMAN", "id": "Q3KPI0-1", "name": "Cell adhesion molecule CEACAM21", "aln": "MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKSDDNTLGILIGVLVGSLLVAALVCFLLLRKTGRASDQSDFREQQPPASTPGHGPSDSSIS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": ":* ..: . : :********* *: .::* * . *..*** :* * * *:* *:.***** *: * ** * .:. * **** * ...: : :* :***:*.**. :.* * : **:**: *::* :: . * :..*.: ::** : :**..:.*:** : *:.*:*:.** :: ***.*: : *.* * *****..**::: ** :.: . ", "identical_positions": 84, "similar_positions": 77, "identity": "28.67%" }, { "cls_id": "homologset.agr.MGI:2141813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGJ0-1", "uniprot_id": "D3ZGJ0_RAT", "id": "D3ZGJ0-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "-----------MSSLREEMDEEELEHPNASPEKRYFPESLDSSDGDEEGVLAC-------------EDLELNPFDGLPYSSRYYKLLKEREELPIWKEKYSFMESLLQNQVVLVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQVHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIINCSPFLISRLSSYYGNVPLLEVRN-KHPVEVVYLSGAQKDPFESVVRLIFEIHRSGEQGDVVVFLACEQDIEKTYEIVCQEGSNLN--PDVGELVVIPLYPKEKCSLFRPVDE-TEKRCQASQRRVVLTTSCGESLIWS-HTVRFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKDMRPLKPAEMQEANLTSMVLFMKRVDIAGLGRCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHGAEEAAVTCWKTFLHPEGDHFTLINIYNAYQDTVLNSANEHCVETWCHNCFLSCSALRMADVIRAELLEIIKRIELPYAEPAFGSQENGLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSYAITKK---MPEWVLFHQFSISENNYIRVTSAVSPELFMQLVPQYY-FSNLPPSESKDILQQAS--GHL-PTTAMDKDQDVCDKCPDATEQRCTVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZS9-1", "uniprot_id": "DHX32_MOUSE", "id": "Q8BZS9-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "------------------MDEEELDHPNASPEKRYFPESLDSSDGDEEGVLAC-------------EDLELNPFDGLPYSSRYYKLLKEREELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLLTSKLSSYYGDVPVIEVRN-KHPVEVVYLSGAQKDSFESVIRLIFEIHRSGEKGDVVVFLACEQDIEKTYELVCQEGSNLN--PDVGDLVVIPLYPKEKCSLFRPVDE-TEKRCQVYQRRVVLTTSCGESLIWS-HTVKFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKDMRPLKPAEMQEANLTSMVLFMKRVDIAGLGRCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHGAEEAAVTCWKTFLHPEGDHFTLINVYNAYQDTVLNSANEHCVEMWCHDCFLSCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENGLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSYSITKK---MPEWVLFHQFSISENNYIRVASAVSPELFMQLVPQYY-FSNLPPSESKDILQQAA--GHL-PTETVNKDQDVCDKCPDATEQRCTIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L7V1-1", "uniprot_id": "DHX32_HUMAN", "id": "Q7L7V1-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "------------------MEEEGLECPNSSSEKRYFPESLDSSDGDEEEVLAC-------------EDLELNPFDGLPYSSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPVIEVKN-KHPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQ-GSNLN--PDLGELVVVPLYPKEKCSLFKPLDE-TEKRCQVYQRRVVLTTSSGEFLIWS-NSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSGYSITKK---MPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYY-FSNLPPSESKDILQQVV--DHLSPVSTMNKEQQMCETCP-ETEQRCTLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYY8-1", "uniprot_id": "A0A8M1NYY8_DANRE", "id": "A0A8M1NYY8-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "-----------------------------MAGNGELSGELGKEEEDSENLFEFG------------DDLELNQFDGLPYSSRYYRLLQERKTLPVWKYRHEFMTLLENNQILIVSGTTKTGKSTQIPQWCAEFCLSAQYQHGVVVCSQIQRRQAVDLALRVADEMDVNIGHEIGYSIPLETCCSNDTILRYCTDDILLREMMSDPLLEQYGVVLVDQAHERTVSTDVLLGLLREVLLQRPELRLVVLSAPPTPETLLTHYGSVPRLHLEA-PSAGEVIHSSSSSSESFYSALRLALEVHRSREPGDVAVFLATEQEVVCACNIITKEASRMS--VSLGELLAVPMCSG-HAGICPPVTE-SPQ----MSRRIFVSCSQLEDLFWSVDSIAFVIDTGVEKRLVYNPRLRASSEVIRPISKCQAEMRKQLTGS--TGKCFCLYPEDVQ---LPAEIHPRILESNITSTALFLKRMEAAGVTHCHFINRPDPEGLMQALEELDYLAALDNDGNLSEMGIIMSELPLEPQMAKALLASCEFDCASEMLTIAAMLTAPSCFIEPPVGMLTEVMRCHMKFQHPEGDHFTLINIYNTFKRSQREP--YFSQEQWCEQYYLCCAALQTADAIRSQLSDVLKRIELPISEPAFGTKTNALNIKRALLAGYFMQMARDVDGSGNYFMLLNKHVAQAHRLSAYGAKAQKLGLPEWLLFHEYSLTDN-SIRTLTHISPHAFVQMAPQYF-FCNLPPSESKEILQNILDRDRTGIPKAKTRPEPKTETQESEAQERCVLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53131-1", "uniprot_id": "PRP43_YEAST", "id": "P53131-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43", "aln": "MGSKRRFSSEHPDPVETSIPEQAAEIAEELSKQHPLPSEEPLVHHDAGEFKGLQRHHTSAEEAQKLEDGKINPFTGREFTPKYVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMP-HLENTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRYSCIILDEAHERTLATDILMGLLKQVVKRRPDLKIIIMSATLDAEKFQRYFNDAPLLAVPGRTYPVELYYTPEFQRDYLDSAIRTVLQIHATEEAGDILLFLTGEDEIEDAVRKISLEGDQLVREEGCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELIEQSYPEILRSNLSSTVLELKKLGIDDLVHFDFMDPPAPETMMRALEELNYLACLDDEGNLTPLGRLASQFPLDPMLAVMLIGSFEFQCSQEILTIVAMLSVPNVFIRPTK-DKKRADDAKNIFAHPDGDHITLLNVYHAFKS---DEAYEYGIHKWCRDHYLNYRSLSAADNIRSQLERLMNRYNLELNTTDYESPKYFDNIRKALASGFFMQVAKKRSGAKGYITVKDNQDVLIHPSTVLGHDAE------WVIYNEFVLTSKNYIRTVTSVRPEWLIEIAPAYYDLSNFQKGDVKLSLERIK--EKVDRLNELKQGKNKKKSKHSKK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. . . * . :* ::* * * ::.:* :*: *. **: : .*: :**:::. * : **::*:**: :. : :: * *:* :: .:.:* ***:****::*.*:** * :*. :..***:* **.:* ** *.: * *. :::*: ***:::**:*:***::*: **:*:::: .:. . : ::...* : : . *: : . . : : * :* :::* : * **: :**: *::: . . : ...: . * * . *: : * : : * .: : : . : :*:* *..:: *****:*..* :: ***:..*: * * .** * **.*: : ..: .:*::* .* :*:: .: : .*:: * ** :*:***:*:***.**::***: :* : *::**:* :: ::.* **:* .*:***.**::.*. * . . . . * **:***:**:.:*:::: : . . **.: :* :* ** **::* :::* :* . : : **::** :*:***:*:. .*: .*: : .:: . * : . : *:::::: ::.: ** : : *. ::::.* *: :.*: .: * *:. : : : .. ", "identical_positions": 179, "similar_positions": 266, "identity": "22.74%" }, { "cls_id": "homologset.agr.MGI:2141847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63625-1", "uniprot_id": "PHRF1_RAT", "id": "Q63625-1", "name": "PHD and RING finger domain-containing protein 1", "aln": "------------------------------MDDDNLDELVAHSPGPDGPPQVGSSELASDAEESSNGHSEDSE-----------DDTGSEQDDDTDGEETEGLSEEEDPEDRSGSEDSED-----GIEVPTAAVETQRKLEASSTPNSDDDAESCPICLNAFRDQAVGTPETCAHYFCLDCIIEWSRNANSCPVDRTIFKCICIRAQFNG-KILKKIPVEN---------TRACEDEEAEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAVPGVDPTHDAAPVSDEEVSLLLADV---VPTTSRLRPRVGRTRAIARTRQSERVRATVNRNRISSARRVQHVPR---YLMSSLLDETIEAVATGLSTAVYQRPLTPRVPAKRKRKAGRRKKVLGRKKTRSRSSVKSKSGGTRAKKRQHRVRRTKGRKLKNEVTARSRIARTLGLRRPVRGTSMPSVYKPVDPSLGLMRADIGAASLSLFGDPYALDPFDSNGE--QSADPPSPLSAKRR------VLSRSALQSHQPVARPVAMGLA------------------------RRQLPAVAPEPSVEEAPVPDLLG----SILCGQSLLMMSSADVVIHRDGSLSAKRAAPVSLQRNSVTQSREESRLRDNLQPGALPSES--------------VSGGLIGDRRPNSGLSCGDRTALRCLPAQIVQTPVRSDSSVTPRSGLSGNLSDESRPKWKHSNSPRLNGSN---VRVGSASTKTMTHSNFP-SKNIAPGHPQKTDPRR--------PDFSKLPRIPKIRRDGSNSTQDQAPASGQTVELPSACISRLTGREGPGQPGRG-RADSEPS----------------------------------------SRGPQETGSHTSGSRPPAPSSHGNLAPLGPSRGKGIGSSFESFRINIPGNTAHCSQLSSPG-FCNTFRPVDSKVQR------KENPSPLFSIKKPKQLKSEIYDPFDPTGSDSSPPSSSPE--SLGSGLLPSEITRTISINSPKAPAFQTVRCVTSYRVESVFGTEMDPDPQPPGEPVSGMLELLGKGPAEGASDLEQEGLGEIEPTEIQGSSARAQRPSPPDPWDDEDGVSCTPFFGSEERTVTCVTVEEP-SVPSPDAPQITTHRIVEFRASSRSRSTSSSRSRKKTKKKKK-VAREHQRTRSSTRSGSRDRTSRSVSP-FTEEHTKRHRAKTKSRR----------------------------------------------------------------------------------------SSSDRASSQDRAKRRKDRD---REHRRGPWGHGR-----CWRKSRSRSGSPGSSSCERHES-----------------------------------------------RRRKRRHSGSRSRGR------------------------DGSPHSSLERDRRHKH-RERSRERMDKKESMTRSRERRRWRSR--------------------------------------------------------------------SPSVEHRT---RRPHSREKH----PHSPEKKGAVREVSPAPAPQGEPRQDGDHSTKPPVSEVSVLPEVVSVLPEVVVADLNPPEVPPVLAESVSCVP--EDLDYGDSVEAGH-----------------------------VFEDFSNEAIFIQLDDMSSPPSPESTDSSPERDFLPNPILPPASLPQNSTLPVTQRE---------------VLPIHSEDISKPAPQPLAPSDQCLLRQDTVETTATTLSTPGVLPMGK-----------------DSPLLSGRGCEVVRPKDAVAPAPLLRSRTLVKRVTWNLQEAEASTP-ALDRDPR---------TPLQRPQRPQEGDWDAEDRALIGFQQAPFSELPPPIHVLQESGLPDADPSQPPGVPRAEGPPAVGTLH------------SAGGILAQVYSPNMPPPLAQPSSIPPYALVNQPSVQLILQGTLPLASCGAAQNLAPVPTMPATASELA----------------------------------------------------------------------------------------------------VPTTN--NSEERTATPKTAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRKHKKTE-AGEEPPTQGAET-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H619-1", "uniprot_id": "PHRF1_MOUSE", "id": "A6H619-1", "name": "PHD and RING finger domain-containing protein 1", "aln": "------------------------------MDDDNLDELVAHSPGPDGPPRVGSSELASDAEESSNGQSGDSE-----------DDTGSEQDDDTDGEETEGLSEEEDPEDRSGSEDSED-----GVEMATAAIETQGKLEASSVPNSDDDAESCPICLNAFRDQAVGTPETCAHYFCLDCIIEWSRNANSCPVDRTVFKCICIRAQFNG-KILKKIPVEN---------TKAC---EAEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECTVPGVDPTHDAAPVSDEEVSLLLADV---VPTTSRLRPRVGRTRAIARTRQSERVRATVNRNRISSARRVQHVPR---YLMSSLLDETIEAVATGLSTAVYQRPLTPRVPAKRKRKAGRRKKVLGRKKTRSRSSVKSKSGSTRAKKRQHRVRKTKGRKLKNEVTARSRIARTLGLRRPVRGTSMPSVYKPVDPSLGLMRADIGAASLSLFGDPYELDPFDSNEE--QSADPPSPLSAKRR------VLSRSALQSHQPVARPVAMGLS------------------------RRQLPAVAPEPSVEEAPVPDLLG----SILSGQSLLMMSSADVVIHRDGSLSAKRAAPVSLQRNSVTQSREESRLRDNPQPGALPSES--------------ASGGFVGDRQPNSGLSCGNRTALCCLPARIAQTPVRSDPSLTPRSGLSRTLSDENRPSRTHSSSPQLNGSN---VRVSSASTKIVTHSSFP-SKNTASGLPQRTGPRR--------PDFSKLPRIPKIHRDGNKSTQDQAPASGHIVELPSTCISRLTGREGPGQPGRG-RVDSEPS----------------------------------------SRGPQETGSHTSGSRPPAPSSHGSLAHLGPSRGKGIGSSFESFRINIPGNTAHCSQLSSPG-FCNTFRPVDSKVQR------KETPFPLFSIKKPKQLKSEIYDPFDPTGSDSSPPSSSPE--SLGPGLLPSEITRTISINSPKAPAFQTVRCVTSYRVESIFGTEMEPEPQPPSEPVSGMLELLSKGSAEGTSDLEQEGLGEIEPTEIRGSTARTQRPPPPDPWDDEDEVSCTPFFGSEERTVTCVTVEEPGVLPSPDAPQITTHRIVEFRASSRSRSTSSSRSRKKTKKKKKKVAREHQRTRSSTRSGSRDRTSRSVSP-VAEEHTRRHRAKTKSRR----------------------------------------------------------------------------------------SSSDRASSQDRAKRRKDRDDRDREHRRGSWGHGR-----CRRKSRSRSGSPGSSSCERHES-----------------------------------------------KRRKRRHSGSRSRG------------------------------SSLERDRRHKH-RERSRERMDKQESVTRSRERRRWRSR--------------------------------------------------------------------SPSLEHRP---RRPPSREKR----AHSPEKKGPVREVSPAPATQGESRQDGDHSAEPPVSEVSVLPEVVSVLPEVVVADLNPPEVPPVLAEPVAHVP--EDLDYGESVEAGH-----------------------------VFEDFSNEAIFIQLDDMSSPPSPESTDSSPERDFPPNPILPPASLPQDSTLPTIQRE---------------VLPIHSEDISKPVPQALAPSDQSLLKQDTVEITTTTPSTPAVVPMTK-----------------DSPVLSARGWEAVRPRDAVAQAPLLRSRTLVKRVTWNLQEAEHSTPAALDRDPR---------TPLQRPQRPQEGDWDAEDRALIGFQQAPFSELPPPIHVLQESGLPDADPSQPPGAPRAEGLPAAGTLH------------SAGGILAQVYSPNMPPPLAQPSSILPYALVSQPSVQLILQGTLPLAGCGTAQSLAPVPTMPATVSELA----------------------------------------------------------------------------------------------------VPTTN--NSEERTATPKTAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKTE-GGEEPPTQGAET-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P1Y6-1", "uniprot_id": "PHRF1_HUMAN", "id": "Q9P1Y6-1", "name": "PHD and RING finger domain-containing protein 1", "aln": "------------------------------MDDDSLDELVARSPGPDGHPQVGPADPAGDFEESSVGSSGDSG-----------DDSDSEHGDGTDGED-EGASEEEDLEDRSGSEDSED-----DGETLLEVAGTQGKLEAAGSFNSDDDAESCPICLNAFRDQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGG-KILRKIPVEN---------TKAS----EEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAAPGVVLAADAGPVSEEEVSLLLADV---VPTTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPG---RLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRADIGAASLSLFGDPYELDPFDSSEE--LSANPLSPLSAKRR------ALSRSALQSHQPVARPVSVGLS------------------------RRRLPAAVPEPDLEEEPVPDLLG----SILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSFQRNSGSLSRGEEGFKGCLQPRALPSGS--------------PAQGPSGNRPQSTGLSCQGRSRT---PARTAGAPVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSVVPGPPLKPAPRR--------TDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEAS----------------------------------------SRVPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPG-FCNTFRPVDDKEQR------KENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPE--RSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTE----PEPPLGPSSAMSKLRGAVAAEGASDTERE-----EPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAK--RKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRR----------------------------------------------------------------------------------------SSSDRSSSRERAKRKKAKD-KSREHRRGPWGHS-------RRTSRSRSGSPGSSSYEHYES-----------------------------------------------RKKKKRRSASRPRGR------------------------ECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSR--------------------------------------------------------------------SPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVS-------PEVATADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGH-----------------------------VFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLA----VAAIQRE---------------VSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEK-AEAPSSPDVAPAGKE----------------DSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESESSAP-AEDRAPR---------APLHRPQKPREGAWDMEDVAPTGVRQV-FSELPFPSHVLPEPGFPDTDPSQ-------------------------------------VYSPGLPPAPAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPA----------------------------------------------------------------------------------------------------SQATAASNSEEKTPAPRLAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKPE-AGEEPPTQGAEG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BA76-1", "uniprot_id": "A0A8M2BA76_DANRE", "id": "A0A8M2BA76-1", "name": "", "aln": "------------------------------MEEDDSQDELINRNVSHGKGKRPAMSIISDDEDNSEGEDESEE-----------EETGSE-GDDDDEEQQEILDEEEDEDEESEDEDAGK-----VLEGAVGNISVD-----AMDLSSDEDSEKCPICLNSFHEQPVATPETCEHYFCLDCILEWSKNANSCPVDRIVFNNIILRKCHGG-KIQKTIAVKKP--------VKPAEEQVEVDLDQTSCEICGGRDREDRLLLCDGCDAGYHMECLTPPLDAVPVEEWFCPECIAN-------NRTSGSEQISEEESSS---LPTTSHSRSRP--TRAIARTQQSERVRASVNRHRITQARTAEQLAPR-YMMQSTWLDETINAVVAGLNTAVYVRDLTPRSRPRRRRKTVKRRKS--KSKSSSTSGGKPSRGVKRRKRKVRRSKVRRKLVVKKETNSRGRIARSLGIKKPKSGSIIPSVYRPSEYSLGSMRAEIGAASLSVYGDPFDLDPFNDREDEIQVLTPSSVMDAKRR------GLSRSALRSHQPVARPISASLS------------------------RQSVTIPQVGVVAEEAPVSDLLG----SILSGQSLLLMDSSDVVINRDGSLKAAKSVSLSLPRNSTTGS-GEMGNTPSSERLMFSYGE--------------AGLSSSPLREPSLVQSSPGSSSTPQNPTSPHIQAPHLSRSQNYPQMQPRAPHRPPNLNLSRPENGHLSISGVRSEPFSRVSNGSFDSAPHD-KDGIARQPPIRKDPPKPV-----WVDVSVLPRIPKIKRD--SGSKSSGSSRSASSVPSGMSLAGNSGRKQAVDNRETGTSQQNRT----------------------------------------LDVQKQTVDRTGASSSFSSSFTSTASSYSASSNSRPSSSSISFRINSSGNPWQTRRLLASGGALFGDDEESTKINN------KSKRILLSSRKKKKDEKCEVYDPFNPTGSDSSDNEPEVEGLEDSAKNARSQMSVGVCEDICNRIKIEPVDMDPVREAGSEICVEVKTSTCKPCQQSPHHSDPMNITVPSGASVSFTKCETMLEPTSCETLGSSFLKTQECTRSSCTDRNVKSELNFKIEAEPTPIRPQSKSLEESLSNLQQTSQHNLVCKELPSVSGVLNATNISVDREEKSHQSQSKDNKQSPSNCQSFHYKDCHKTKHSRSKEKRRSRSRSRDRR----------------------------------------------------------------------------------------RSRSKSKERQRSRSKERKHLHSRDKRCS------------SSSSRERSSSGKKVICERSDN-----------------------------------------------RGRERQR----------------------------------------KRPKERRYSRSRSYSRSRSRERKSMSKCQGDSRSK--------------------------------------------------------------------RQKSELRSTSRERKKREDQLDKSLHREKSFQESIEPMSIELHEASVGANKTTESVKMERDARLCDREIMCIKPSIKELEPRSVNKSHGLGSSKHGDWSRILKDGADGISLDL-----------------------------LKSTEIKQEELWPISAVSEFKDIKKEDE-PNFSLCRESGGVKEIKTEIETVGLISKE---------------SPDFNKSKLYSPDLEKGYAGFQDEIKMEEMIIGKEKIKTEQIWPDED-----------------ESPISDNPLVISLDIHDIDALDIKKEPTESYHLPPLEEDKKMSPLQLPILPIKQ---------EPVISSDEDISVDYLIDNLDFIKKEMSETFMPDSAETTNPKFSIPESTAENTQNSETVPAVLKSKSQ-------------------GKRVTWNLEEPVEPQS--EKLSKLAMFKLKLKQEGSRRSAATPQLSNQDKASKVTATLSSLQ----------------------------------------------------------------------------------------------------SPQGESSKPKSRKDVLQDPNEKEKVVGYMKKLHMQERAIEEVKLAIKPFYQKRDITKEEYKEILRKAVQKVCHSKSGEINPVKVANLVTAYVEKYKHARRHRKEE-SGQSRHEDVPNDFQTSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNE0-1", "uniprot_id": "Q9VNE0_DROME", "id": "Q9VNE0-1", "name": "PHD and RING finger domain-containing protein 1", "aln": "MSDRDSDAVSDAGPRLSQQRGQRNRRIIMRIEFKDSEDSASDQDRDDRPSCSAATRLRRSTRRQEVASHSDSDSVPRKSTRKLRNRYGPRSDCSSSGSDIDQLPTRTRKRKKVESSDEEEPERTPNAVGRIQPMPADPDDGFSSDISSNDLLEKCPICLLTFRQQEIGTPATCEHIFCAACIDAWSRNVQTCPIDRIEFDRIIVRDSYASRRVVREVRLDLSKSNTELVVDDEADTAALSEEEVTNCEICESPDREDVMLLCDSCNQGYHMDCLDPPLYEIPAGSWYCDNCIDSDDEDDNEQLELADDLDQLYEDIRGMGLPETRLRVREVQEPPRILRTRQNERIRAAVLRRTRSGATSAEDSTLTRTRTRTTTTTTTTTTTTRRTTTSTKKRPVQRRRRRRTRYRTYVVEYDLNNFDEKFALKTSKKVIRRRRRRRRRGVATASSEGPGRRLSASKRLAEQMGVKSEGFQSSHLSGGTASSFSLFGNANDLEYFSDSEPDAVSQISSAGLGSTAVQTSVRIGSIGAPRIRKALLQGKARIAAPPTAPTSAPAADILSSILDLQDRWHDASRNLGEVHIRADGTLNIPQRPAPTATEAPLPKAGTSKTEKHLTQAPLYQQGGGGPNYNRGGGAGSSDSYNNRYSGNTSYRGGGGGGAGGSSGGSGVPSSSGEASSRHLTGEGDGQGGGGFGNQNFSSSGSNNNTNMSSFIPFHLRFNTPTRQQQPRQQNVLPANQPTPPFPGSAPPPAPVASSSNNFSGQTPMFAAPLNHHPAPVMGMPVVLSIPPPPMPPASLPWNSPLFKITPLQQAPAKSNDGNQNDDVDNCPNFSIYSQESQAVANASAMPSGVPHGPADASDKDDDDMNEDLVQLDDDDEDTDIPLPLGPEPEPVPEKVPKSSDDDLYEPENPTEEPEEPEMFEESCDAVPTEKSESSDHEPSNSNVQAAAPEENDAEEARTRSTPSPLVKEDRAADRDRAKGVLELYDDSDWEELDIDKPKEFEKALLTETEAQVSPKRAPSKRPP--SKKDTSLERDVNESGSEHEQDRSYTPCLDEKNLAEEEEAGTTHQNNVSTSPKTRSSKVSGDEDEPEKAVGTDIQSEDELNNENESPRRSRSRGTANNKKDKSKSRSKRNKGETFKKVGKRQKDRNYRGDKSEPDRSPRPDSRSLTPKMRSKSPRVSKSISRSRSGSRSRCKSKSFSRSRSRSPSRSRNRRRRNSRSKSYSRSHSRSRSRSNSHSRQRFSFRGRDHQRGFFRGRGGLRLNYRNQQFHNRPFQHYGQNYHQNQNYHHQHNQHQNYFPPNQHGQHQQYFQRPKRRELPRYDVRNVVGTSRHQTQAKDRYGRDAMRSHRSRSGRRNSRSFSRSVSRDSRVSLRSRSGSPKRRSFSMSPTPPPGTSPPPHKHGRGRQTSTNRRYARSPSPAPSPRNERATSPVQSVHSRRSRSHTPNRINGDGNRSSLYMGSPHYTPRISRSRSRSRSKSPKDMHKKKKKKSDKKKRRKRTGSSSPTTAARMRRISRQRDPFEDADDFLAPQRKRKKAGITTGQWSPSPSPGRCDFLHDSALQDKNSSWTPPLGTPKGGHYNNDGGLTPKKTKRKRDKSKKKRKQHQLEKPRKEKKRKRRTQTPEPLPSKEVFASGNNILVSVSFNKESNTNNASATLSSQQQSVVTIPPGREDLLSNRMTSMTSMASMASNSNICSAVGAVKKTKRKRKKLEAKPVAIIDLERSPFQVHQEPADVIVLTDSEDATEPLSSRRERERDRDHELMRENGQREKTPQVGSLDAIMETSYENMTQSTGPKTPPEPPLVKFNLPTKKIQHKVRNNPLHEDVDDINSADELEASCSMAPAEQTPQHGHASHDGGQKIGPNTPPESGPCSPDAYDPFEPTKSPSLSPRSPTLTPSQNLDQQTVSMPASGAIGPGSGDKGESDGAHVTGSNASTNTQAQGNALNPVDLVMALMNKPNQSGSIQQESEVSSAQYISSSSLSLSLGVGSSTGGGGGGAGGGDNHDKTADGKTITVLSNVLLTSSSVVSSSQHIPSISSPTPPSKKLTPLPKAGGSVASSSSGVGNIPTTSSGIGGTRNGSGLGNAGGSSNALDDSFSMEIESPYSPGSADYEDLFEPPIPLEASRRAKGGATGGKVEIFDNLFGSSSPISNIRMTSRYNTAVGKKSNRTKADRKSKVKGARNPDFYDDVPNSATDLQNKDRLLRKLNRQERVVEEVKLVLKPYFNKKAITKDDYKDIMRRAVPKICHSRSGEINPHKIKNLIDAYVRKFRAKHKKLSLLNTGQVSSAVKCAAYLKKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. :: . . . . .. . .. : ... . . . .: : . .. ..* . .: : .*:: *.***** :*::* :.** .* * ** ** **:*.::**:** *. * :* . . :: : : :. . : : * **:* **** :****.*: ****:** *** :*. .*:* :* ..: . :* * . . * **:*.**:**:* *. : * .:. . :: : :.. .*:. * : * : : :: . . . . . * ::: : . .: *:*. :*:: : * . . ** :: * * . :.. . . :.* * :* * . *.: * : *: * *:.. . * .* .... :*.*. : : *: . .. . . . : . * . . * . . . . . :. : . * * ..: * : * .* . . . .:: :. :.: .:. .. . * . : . * . ..: . .: . :.. . . . ... . .* *: . : :. * . ::. . . . : . .. . * . . : : * . . : . . . . . . : : . . : . . : . : .: ..:* :.. . . . .. * *:.::.*: * ::. ::* : *. * . . *.**.* . . :.: : .: .:: :.: .* . : .: : *.: . * : .:: :. . : . . . .. . * ..: : . . : . :. . . . . . . : . : . . : : : * . ::* . : . . : :: . . : .: . : . : ...: . : : . * . : . . .. .. . :. * :.. . . . : : ::**: ***.:*****.:**:::*: :**::**:*:*:** *:***:****** *: **: *** *:: ::: . *: ", "identical_positions": 166, "similar_positions": 422, "identity": "7.22%" }, { "cls_id": "homologset.agr.MGI:2141857", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P788-1", "uniprot_id": "ATF5_RAT", "id": "Q6P788-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTER------------VDFTALLPLEAPLPPGTLPPPS-------------------------------------------------------PAPPDLEAMASLLKKE------------LEQMEDFFLDAPLLPPP-----------------------------SPPPPPPP--APSLPLPLP---------LPTFDLPQPPTLDTL--DLLAVYCRS----EAGPGDSG---------LTTLPVPQQPPPLAPLPSLSRPAPYPSPASTR--GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70191-1", "uniprot_id": "ATF5_MOUSE", "id": "O70191-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTER------------VDFTALLPLEAPLPPGTLPPPS-------------------------------------------------------PAPPDLEAMASLLKKE------------LEQMEDFFLDAPLLPPP-----------------------------SPPPPPPPAAAPSLPLPLP---------LPTFDLPQPPTLDTL--DLLAVYCRS----EAGPGDSG---------LSTLPVPQQPPPLAPLPSPARPAPYPSPASTR--GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2D1-1", "uniprot_id": "ATF5_HUMAN", "id": "Q9Y2D1-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTER------------VDFTALLPLEPPLPPGTLPQPS-------------------------------------------------------PTPPDLEAMASLLKKE------------LEQMEDFFLDAPPLPPP-----------------------------SPPPLPPPPLPPAPSLPLS---------LPSFDLPQPPVLDTL--DLLAIYCRN----EAGQEEVG---------MPPLPPPQQPPPPSP-PQPSRLAPYPHPATTR--GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P756-1", "uniprot_id": "A0A8M9P756_DANRE", "id": "A0A8M9P756-1", "name": "", "aln": "MAYNWMTKTFDTYPNSTSTESSPGSSIPPSPLEHDVQMPSDLEVMTNLLKEELAQLEDYYLYESAPMKLEKWQKCDKSLQAMATQSYYQLPCASYNVNQSETNPRLVSLA-AGELDLRGFCGGSVNRPKMSRPAPYSYIRTHCNSQRISSNGCKDVEVFEKETWTFKGTHSGYAELAFDQCSVDKSFGKNHGSAKKVRECAILLKEEEKSCFSEDVFYRAEMMRSYDLAGSLEPHHRRESQCHGMKMLGHDGIAMPILQCAENESCPPPYKQSDVAECYFHQITANLEPYHGFMNEIDQPIRTDIQNN--DYLHHECLGDQSFECLSGDSV---------GSSLELPVQKPLQRSRESQCVFKPDVKVGVERNHGERKQKKRDQNKSAAHRYRQRKRAEQDCLEEELHGLEGRNRELRDKAESVEREIQYVKDLLIEVYKARSQRLKEDSSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VID3-1", "uniprot_id": "Q9VID3_DROME", "id": "Q9VID3-1", "name": "", "aln": "-----MDATFHQTMESLQLPKELYWDLKMEPQSPTSVLGSDLFPLTD--SNDTEWLYDDNFANGITLIGDDEALTLEEVASLQLLSDEEMVVEIFDLKDEECLLDQKATLNCIDYDSNSFQPNINVITQAIVPANKVQFG-----------------------------------------ASSDAASLPSAADYQLNDGPSLILQQLTPPQS------PPQFDAYKQAGDAQPKP---------VLVKAEQKVQCYTPDVTHAASATPFNFTNWVGGSEIARENQLVDDIVNMRAKELELSTNWQQLNEDCESQASSSLDSRSTGSGVCSSIADADEDWVPELISSSSSPAPTTIEQSASQPKKRTRTYGRGVEDRKIRKKEQNKNAATRYRQKKKLEMENVLGEEHVLSKENEQLRRTLQERHNEMRYLRQLIREFYHERKR--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :. . * * . : . . : :. * * .: . * : .:. . *: :: : : . * ...* . : : . : * . . . . * . . * . . . * :** :*::***.** ****:*: * : : * : *. .*.:*: :. ..*::*:::*: *.*: *.: ", "identical_positions": 37, "similar_positions": 72, "identity": "8.19%" }, { "cls_id": "homologset.agr.MGI:2141861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53680-1", "uniprot_id": "AP2S1_HUMAN", "id": "P53680-1", "name": "AP-2 complex subunit sigma", "aln": "-MIRFILIQNRAGKTRLAKWYMQFDDDEK--QKLIEEVHAVVTVRDAKHT-NFVEFRN-FKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62743-1", "uniprot_id": "AP2S1_MOUSE", "id": "P62743-1", "name": "AP-2 complex subunit sigma", "aln": "-MIRFILIQNRAGKTRLAKWYMQFDDDEK--QKLIEEVHAVVTVRDAKHT-NFVEFRN-FKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62744-1", "uniprot_id": "AP2S1_RAT", "id": "P62744-1", "name": "AP-2 complex subunit sigma", "aln": "-MIRFILIQNRAGKTRLAKWYMQFDDDEK--QKLIEEVHAVVTVRDAKHT-NFVEFRN-FKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VDC3-1", "uniprot_id": "Q9VDC3_DROME", "id": "Q9VDC3-1", "name": "AP complex subunit sigma", "aln": "-MIRFILIQNRAGKTRLAKWYMNFDDDEK--QKLIEEVHAVVTVRDAKHT-NFVEFRN-FKIVYRRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQLLTLNSLE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00381-1", "uniprot_id": "AP2S_YEAST", "id": "Q00381-1", "name": "AP-2 complex subunit sigma", "aln": "MAVQFILCFNKQGVVRLVRWFDVHSSDPQRSQDAIAQIYRLISSRDHKHQSNFVEFSDSTKLIYRRYAGLYFVMGVDLLDDEPIYLCHIHLFVEVLDAFFGNVCELDIVFNFYKVYMIMDEMFIGGEIQEISKDMLLERLSILDRLD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*** *: * .**.:*: ...* : *. * ::: ::: ** ** ***** : *::********* : **: *:: ** ** *****: :* ******:******** ::****:.***:* *: :*::* *: *:", "identical_positions": 70, "similar_positions": 39, "identity": "47.62%" }, { "cls_id": "homologset.agr.MGI:2141866", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZG1-1", "uniprot_id": "RIC8A_RAT", "id": "Q80ZG1-1", "name": "Chaperone Ric-8A", "aln": "MEPRAVADALETGEEDAVTEALRSFNREHSQSFTFDDAQQE-DRKRLAKLLVSVLEQGLSPKHRVTWLQTIRILSRDRSCLDSFASRQSLHALACYADIAISEEPIPQPP------------------DMDVLLESLKCLCNLVLSSPTAQMLAAEARLVVRLAERVGLYRKRSYPHEVQFFDLRLLFLLTALRTDVRQQLFQELHGVRLLTDALELTLGVAP-----------KENPL-VILPAQETERAMEILKVLFNITYDSVKREVDEEDAALYRYLGTLLRHCVMADAAG-DRTEEFHGHTVNLLGNLP--------LKCLDVLLALELHEG---------------------SLEFMGVNMDVINALLAFLEKRLHQTH---RLKECVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGDLLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEG--QYSEDEDTDTEEYREAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRLIQPMGMSPRGHLTSLQDAMCETMEGQLS-----SDPDSDPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TIR3-1", "uniprot_id": "RIC8A_MOUSE", "id": "Q3TIR3-1", "name": "Chaperone Ric-8A", "aln": "MEPRAVADALETGEEDAVTEALRSFNREHSQSFTFDDAQQE-DRKRLAKLLVSVLEQGLSPKHRVTWLQTIRILSRDRSCLDSFASRQSLHALACYADITVSEEPIPQSP------------------DMDVLLESLKCLCNLVLSSPTAQMLAAEARLVVRLAERVGLYRKRSYPHEVQFFDLRLLFLLTALRTDVRQQLFQELHGVRLLTDALELTLGVAP-----------KENPP-VMLPAQETERAMEILKVLFNITFDSVKREVDEEDAALYRYLGTLLRHCVMVEAAG-DRTEEFHGHTVNLLGNLP--------LKCLDVLLALELHEG---------------------SLEFMGVNMDVISALLAFLEKRLHQTH---RLKECVAPVLNVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGDLLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEG--QYSEDEDTDTEEYREAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGHLTSLQDAMCETMEGQLS-----SDPDSDPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPQ8-1", "uniprot_id": "RIC8A_HUMAN", "id": "Q9NPQ8-1", "name": "Chaperone Ric-8A", "aln": "MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQE-DRKRLAELLVSVLEQGLPPSHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSEGSVPESA------------------DMDVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELKGVRLLTDTLELTLGVTP-----------EGNPPPTLLPSQETERAMEILKVLFNITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAG-DRTEEFHGHAVNLLGNLP--------LKCLDVLLTLEPHGD---------------------STEFMGVNMDVIRALLIFLEKRLHKTH---RLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEG--QYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQDAMCETMEQQLS-----SDPDSDPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q642H7-1", "uniprot_id": "RIC8A_DANRE", "id": "Q642H7-1", "name": "Chaperone Ric-8A", "aln": "MDLNAIIEKMETGDQDAALTALQTYNKEKSQCFSFTSGEEE-DRERLGELVLSFLERDLQPSCQLACLETIRILSRDKKSLSPFATRHAMQILIRHAGLGQGEGVTPEIP------------------DLEVIVEALKCLCNIVFNSEAAQEAAADLQLMVGLAERLKQCREPQWNHDVRFFDLRLTFLITALRVDVRAQLAHELRGVSLLSEALDATFGLCWPDMYEVARAGFDGCSELPPLGRQETERVMEILKILFNVTFDSNRRHVDEEEAATYRHLGAILRHCIMSSAEGEERTEEMHSHTVNLLGNLP--------LPCLDVLLMPKVQQG---------------------SIEYMGVNMDAVKVLVEFMEKRLDRGN---KLKETLLPSLNLLTESARIHRETRKFLRNKVLPPLRDVKNRPEVGNALRNKLVRLMTHIDTDVKHCAAEFLFVLCKESVSRFIKYTGYGNAAGLLAARGLMRGGRDPG--HYSEDEDSDTEEYREAKPHINPVTGRVEEEQPNPMEGMTDEQKEYEAMKLVNMFDKLSREQVIQPMKIGADGKMTSMEPHELHHLASQQFGESNNSDSDSDTN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W358-1", "uniprot_id": "RIC8_DROME", "id": "Q9W358-1", "name": "Chaperone Ric-8", "aln": "-METEHLKRLEAKEADHIPAILDEFNTKNADLLVFDSFRTDNLWHELWLAIFGILDDQRLSHLHTQCLNTVRILTRDEFSLQTNYIEQEVNTLLKLARIEAGSLKLPATPDELKQEEREEPQLEPSQAQSEVIAEALKCLCNLVYQSSDCRRQCLRQHCLDAILKRVASSMR--HPCALEYYDMKLLFLLTALEPAARSRLQIDLNGLTYMTKWLDDKLGEDS-------------------VGEEQLNIICELLKVMFNVTSAPDK-SPNEYEIQSLHLTGVLRELLLRFGDLATEKDRAVVTHAINLLTNISGSCLTELTLRCSNAELESHKEREQDNEKEKDTEAGAGAKPRECCSQCFEKRNVRSLDVLLRYLRQSLAQQEAEASSHELLSPVLTVLVKCARSDRVMRHYLRQEILPPLRDVSQRPEVGQELRNHLCRFLTLPAMILRDLSAELLFVLCKENVGRMIKYTGYGNAAGLFAKRGILDCRRVEGTDYSSDSEDSDTEEYKQQQQGINPVLGCVEPRSKSHLDDISEEQKEYEAMQLVNLIEQLRQGGIVKPAMIDKDGRPQPLEHILQLQEELPQQ----QLDQKRKT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: : * * :* :::: : * . . : ..* :...*: . : *:::***:**. .*.. .: :: * * : .. * . : :*: *:******:* .* .: . : : : :*: . :.::*::* **:***. .* :* :*.*: ::. *: .:* : :: : *:**::**:* . : :* : : *.: . : . :: . . *::*** *:. * * :. * . . * : *: : .*: ::.: * : . :* : * *.:*.:.** .* *::*: ::******* *****: ***:* *::* :: :**:*****.*.* *:************:* **:: * * *:.**:**:**:: : **** * ** . . ::.:::****:***:**.::::* : :::* :. *: .:: * . .. ", "identical_positions": 142, "similar_positions": 175, "identity": "23.63%" }, { "cls_id": "homologset.agr.MGI:2141867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZLP4-1", "uniprot_id": "A0A8I5ZLP4_RAT", "id": "A0A8I5ZLP4-1", "name": "", "aln": "MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSGISELFISSTDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQELELELCKKHHFGINKPEKIVPSPDDSK--------------------------------FLLKTFTNIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSESFYYSLTYDLTNSVQRQSTGEKDGRPLWQKVDDRFFWNKYMIQDLSEIGTPDVDFWIIPIIQGFVQIEELVVNY-EPSDDDKSSPETPPQEATCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFIQTRGSVPVFWSQVGYRYNPRPRLDKSEKETVDCFCAHFEEQLKIYKKQVIVNLVDQAGREKIIGDAYLKQVLLFNNPRLTYVSFDFHEHCRGMKFENVQTLTDAIHDIILDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRTYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLSRFKDAYRQAVIDLMQG----------IPVTEDLYSIFTKEKE-----------------------------------------------------------HEALQKETQRSHQELISQLLQSYMQLLLPGDEKFHGGWALIDCDPSLTDAAHRDVDVLLLLSNSAYYVAYYDDEVDKVSQYQRRSLEDLEKIEIGP--EPTLFG--KPKFSCMRLHYTCKEAGGYFHTLRAVPRSPEEDGKDTLQCIAEMLQITKQAMGLHVPIIERKLERKSSKPHEDIIGIR----SQNQGS-LAQGKSFLMSKFSSLNQKVKQTKSNVNIGNLR---KLGNFTKPEVKVNFLKPNLKVNLWKSDSSLETME-NPGVMGNKVQGESDGDVSSDNDSYHSDELLTNSRSEEGKQLANSLESAGPTDYLLPSCGIIASAPRLGSRSQSASSTDVSIHAPSEATVGHGHELGKGLESPLKKSP---SADNIHTLTGFAKPMDVYCQRFVQDAQNKMNALSEVRAVAQNS-EEGNHKTNPVSNEETQSESVEQMPSRPSQLNVSCSVTGPQLLSVEPAHPAVSQKTPGSGSSLLDLEAGLCVTPS-SESSS-RAVSPFAKIRSSMVQVANITQAGLTHGINLAVAKVQKSPAEPEVVNEIQQNELKNMFTQCQTRIIQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDA1-1", "uniprot_id": "SAC2_MOUSE", "id": "Q8CDA1-1", "name": "Phosphatidylinositide 4-phosphatase SAC2", "aln": "MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHS----------DLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQELELELCKKHHFGINKPEKIIPSPDDSK--------------------------------FLLKTFTNIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSESFYYSLTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYMIQALTEIGTPDVDFWIIPIIQGFVQIEELVVNYNESSDDDKSSPETPPQDSTCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHHHTLSFIQTRGSVPVFWSQVGYRYNPRPRLDKSEKETVDCFCAHFEEQLKIYKKQVIVNLVDQAGREKIIGDAYLKQVLLFNNPKLTYVSFDFHEHCRGMKFENVQTLTDAIHDIIIDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRTYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLSRFKDAYRQAVIDLMQG----------VPVTEDLYSIFTKEKE-----------------------------------------------------------HEALHKESQRSHQELISQLLQSYMQLLLPGDEKFHGGWALVDCDPSLTDAAHRDVEVLLLLSNAAYYVAYYDDEVDKVNQYQRLGLEDLERIEIGP--EPTLFG--KPKFSCMRLHYRCKEAGGYFHTLRAVPRSPEEDGKDTLQCIAEMLQITKQAMGLDVPIIEKKLERKSSKPHEDIIGIR----SQNQGS-LAQGKSFLMSKFSSLNQKVKQTKSNVNIGNLR---KLGNFTKPEMKVNFLKPNLKVNLWKSDSSLETME-NPGVMGNKVQGESDGDISSDNDSYHSDEFLTNSKSEEDKQLANSLESVGPIDYILPSCGIIVSAPRLGSRSQSASSIDVSTHAPSEAAAGPGSELGKGLESPLKKSP---SADSIHTRTGFTKPMDVYCQRFVQDAQNKMNDLSEIRSVAQKS-EEGSHKTNRVSNEETQSEPMGQTPPRPSQLNVSCSVAGPPFLSVEPVHSVLSQKTPSSGSSLLELEAGLCVTPS-SESSSSRAVSPFAKIRSSMVQVANITQAGLTHGINLAVAKVQKSPAEPEAVNEIQQNELKNMFTQCQTRIIQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2H2-1", "uniprot_id": "SAC2_HUMAN", "id": "Q9Y2H2-1", "name": "Phosphatidylinositide 4-phosphatase SAC2", "aln": "MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHS----------DLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQDLELELCKKHHFGINKPEKIIPSPDDSK--------------------------------FLLKTFTHIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSESFYYSLTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQG----------IPVTEDLYSIFTKEKE-----------------------------------------------------------HEALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLSNSAYYVAYYDDEVDKVNQYQRLSLENLEKIEIGP--EPTLFG--KPKFSCMRLHYRYKEASGYFHTLRAVMRNPEEDGKDTLQCIAEMLQITKQAMGSDLPIIEKKLERKSSKPHEDIIGIR----SQNQGS-LAQGKNFLMSKFSSLNQKVKQTKSNVNIGNLR---KLGNFTKPEMKVNFLKPNLKVNLWKSDSSLETME-NTGVMD-KVQAESDGDMSSDNDSYHSDEFLTNSKSDEDRQLANSLESVGPIDYVLPSCGIIASAPRLGSRSQSLSSTDSSVHAPSEITVAHGSGLGKGQESPLKKSP---SAGDVHILTGFAKPMDIYCHRFVQDAQNKVTHLSETRSVSQQASQERNQMTNQVSN-ETQSESTEQTPSRPSQLDVSLSATGPQFLSVEPAHSVASQKTPTSASSMLELETGLHVTPSPSESSSSRAVSPFAKIRSSMVQVASITQAGLTHGINFAVSKVQKSPPEPEIINQVQQNELKKMFIQCQTRIIQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E7C5-1", "uniprot_id": "SAC2_DANRE", "id": "A8E7C5-1", "name": "Phosphatidylinositide 4-phosphatase SAC2", "aln": "MELFQAKDHYILQSGDNALWCSRKDGSMAVRPATDLLLAWNPVCLGLVEGIIGKMQLHV----------DLPLGLILIRQKALVGQLPGDHKVYKITKIVVIPLSEDEPQDLELELCKKHHFGINKPERITQSPDETK--------------------------------FLMKTLSQIKSNVGAPIKKKVKENKEKERLERRLLDELYKIFMDSDSFYYSLTYDLTNTVQRQGELGKSDQPLWKRVDDRFFWNKHMIKDLVDLQAPQVDFWVIPIIQGFVQVEELVVNYNESSDEERSSPETPLQEPTCVDDIHPRFTVALISRRSRHRAGMRYKRRGVDTDGHVANYVETEQLIHVHSHTLSFVQTRGSVPVFWSQAGYRYNPRPRIEKGERETMPYFASHFEKEVETYKKLVIINLVDQNGREKIIGDAYLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAIYDIITDMRWAWVDQAGVICQQEGIFRVNCMDCLDRTNVVQAAIARVIMEQQLKKLGVMPPEQPLPLKCYRIYQVMWANNGDTISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMG----------HPVTEDLYSIFSKEKE-----------------------------------------------------------HEEKEKESQRGAQEQVSLLLQTYMQLLLPDDEKFHGGWALIDCDPSLIDATHKDVDVLLLLSNSAYYVAYYDEEADKVNQYQRLSLEGLEKIEIGP--EPTLFG--KPKYCCMRLHYKNGETSGYFHTLRSVTRNPEDDGKDTLQCIAEMLRITKQAMGLDVQVVEKKLERRHSKPHEDIMGIQGKAVDQVLGSGLAQGKSFFLNKFSTLNQKVKQTKTNVNIGNFKPLGKLGTFSKPEVKVNFLKPNLHMNLWKSDSSLETHDSNTGSGALKDHGPHSEEISSDSDSYNSDEQPCSGSREN-------------VDYVLPSCGIVASAPRLGSRSQSIGSVEIAVPSVIRVTGCDEKTMDS-LSVAADQSPGAASEAEEAILIDFGTPIDVYCHQFVQDAKTKPIEVFEEVAPAPKP--QGPQVPLAPDAKLGSSHSQNQLP-RPSQLEVESNVHGANLLTVQPVGSATSCGSQKS------LEG--ITGPSSADSNGSRVVSPFAKIRSSMVQVASLTQAGLTQGINFAVAKVQKSP-EPDAVNETQENELRAMFTQCQTRIIQI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KI33-1", "uniprot_id": "Q0KI33_DROME", "id": "Q0KI33-1", "name": "", "aln": "MEVFQTDSHYIFVKRDKSLWWHRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPN----------VYEPHLVVVKEASAVGVLYPPHLVYKIKSICILSADD---PDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKNTTQQAANLATKQVKSSVGIREPRHIERRITEELHKIFDETDSFYFSFDCDITNNLQRHEAKSEESQ---SQPDERFFWNKHMIRDLINLND---KTWILPIIQGFMQVENCVIGN-------------------------ECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRHHQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQSGKEKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRFFIQNFADSFRQCIIDLMQGQLLRAEDLQEDEVLSTILQILTPETRPPLHGYYNPGVLGPELQLLESIVTTSYYLARFKDSYRQATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLVEDCRRLLLGTAQYPVGAWGLIDADPSSGDINETEVDTILLLTDDCYIVAEYDSHLDKIVRFEKVQLTQVRLIELGMHQQTKIFQGSAPAHLCLRLNYSVDEQEGYFHMFRSAN-------LRFFNNMAYVIKTQEEVAESMTSIVEMFRIALDNAGNTEVRYITGGVLQRRKSKLPTLDVPRGMPRNLSESQLVQLSSKALSN-------MAGQFSK--LGQTFKKPQAHPSSLAATMNPQVMR------------QRDSEIESGQE----------------------------------AEKAVFTLGRKHRNSNSASSTDTDEHDNSLYEPEVDSDVEIAMDKSNYNEN--AFLPSVGIVMGNQKEDSPSSSDEIRHLEQKDSMCKTTEDVLTISITSVTDHVGLPTGLLENAPAIRPITPNPLICVEAHEAFDDREEGVKPVSSTSARDLSLPG-----------LPTHPEANKLKQLTSPLSKLAKNIGLNLDPRKIATKTGVLSPTILSAENSPPERDPSSRDHLLELWEAEKCKTKLIAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**:..***: . :.:** *: . : ::.. ** . : *:*:..*::* :.* *::::: : ** * * * *:..* ::. .: : :* *.** . :.. *..:.: :*. :: :*:.: *. :* .::***: :** *:* :::***:*: *:**.:**: ...: .: *:******:**: * :: . *::*:****:*:*: *:. * :**:********* ******** .*: ********:: .: * *** *.*****::*** **:*.* **:::. ** * ** :::: * : *:***:* *:** ***** .:*: ** .* **:****::****:****.:* **: * : * *: *:**:*:.:****************:**.:.::*.** ***: ** *:* : : ::****** ******** *****:*******::*:****:*****:::..* *::**.:**** * * . : .*:: *.. : .:: * . *:: :*** : *.*.*:*.*** * . :*:.:***:: .* ** **.. **: :::: * :. **:* :..:* * . *:**:* * **** :*:. :: :* ::: ::. ::* . : :: * .: .. : . : : : .* *: :.. :. * *:* : .* **: : . : . :. . ::.*..: : : : * .*:* .* : : . . :. . . . . . ::. : * . . . .: . . .* .. . *:*. .. : . . .. : .**::*: ..: . : . . *: .. :.. .. :. :*:*::* :", "identical_positions": 307, "similar_positions": 331, "identity": "24.35%" }, { "cls_id": "homologset.agr.MGI:2141874", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9A0-1", "uniprot_id": "G3V9A0_RAT", "id": "G3V9A0-1", "name": "", "aln": "-------------------------------------MPEGARGLSLSKPSLRLGCGHQGE------VCDCAAVSDTPTAAPAAPNMASPRGSGSSTSLSTVGSE-GDPSP----ACSASKPEP------------LPEPPIRLHLSPVGIQGSVKLSMLERVAR----------EIVETERAYVRDLRSIVEDYLGPLMDGRALGLNVEQVGTLFANIEDIYEFSSELLEDLEGCSSAGG--IAECFVQRSEDFDIYTLYCMNYPSSLALLRELS-LSPPATVWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGPDTGGREMVEEAIVSMTAVAWYIN-----------DMKRKQEHAARLQQEVQRRLGGWTGPELSAFGELVLEGTFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGPEYTYKGHIFCCNLSVSETPRDPLGFKVSDLTIPKHRHLFQAKNQEEKRLWIHCLQRLFFENHPASIPAKAKQVL---------LENSLHCAPKSKHIPEPPTSPLDSPRPRDARSFTPSRRNPAPSPRLSGS---RRGRRQSE-SKDPYVILPQNDKPQVKHAGSEGELHPPSELQPPVTAPGPPEDLEDAGPP----TLDPSGTSITEEILELLNQRGLRDSGPATHDIPKFPRDSRVPVESETLPFQALPS--RESSEEEEDEE--LEKDEREPSPLHVLEGLEGSSAAEVPCIPSLPKIPSDMPDLPEIP------EAPCLPSLSDIPGVFEVPCLSPMSSVPDIPSLANTPSFPCGSWLPGPLQEAAQSQATRRELLTGSNLGRLSEPPSESRAGQEEDTEGVSFPAVQTQDGTPVQGFPEELEYRSCSEIRSAWQALEQGQLARPGFPEPLLILEDSDLSGGSTSGKTRMPHSERSASRVRELARLYSERIQQMQRAETRASTN------------APRRRPRVLAQPQPCPCPPQEEAEPGALPAFG-HVLVCELAFPLNCAQESVPLGPAALVQAATPLCTQGDDLSGQSLTVSDLPKQGHLSNNCIPPPVPLPGQS-------NFQSLQVPSASLLPKQD-PPDVQLPTASTLPDTGQLQ--VPAAAPSTEHRNYVEIQVQST---------------TTSLPGQECPADFQMPTTAALPRQEGHEDSRSPNSAPGAEQRDVGVDQGPTAVDGQAVSPLPACTSSPDHHQIPATPLPLSPDLPDMEGAGALPLPAQQGHPDCCVPCDPLPSLPQDV---QTPTVIPMSQPQGLTDVRAKVPPSFPTQ------------------EEAPEFLG-------PEPSLTDTPAPRLLPSSGQQNTTDGHVSTAAVPCPEQGCPQDIQGLITSPVQTTMELPKPRG-LVSRVATSESLDLTPPHSPSLSTRQ---LLGPSAAALSRYLAASYISQSLARRQGPGGEGMAASQGHWSSSAPTSRAPSPPPQPQPPAPPARRLSYATTVSIQVGGGGRLRPARAQVRLNHPALLAAPHP--GAFGPSQGPEGS----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6KAU7-1", "uniprot_id": "PKHG2_MOUSE", "id": "Q6KAU7-1", "name": "Pleckstrin homology domain-containing family G member 2", "aln": "-------------------------------------MPEGARGLSLPKPSLRLGCGHQGE------VCDCAAVSDTPTAQ-AATTMASPRGSGSSTSLSTVGSE-GDPSP----ACSASRPEP------------LPEPPIRLHLLPVGIQGSVKPSRLERVAR----------EIVETERAYVRDLRSIVEDYLGPLMDGRALGLNMEQVGTLFANIEDIYEFSSELLEDLEGCSSAGG--IAECFVQRSEDFDIYTLYCMNYPSSLALLRELS-VSPPATLWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGPDSGGREMVEEAIVSMTAVAWYIN-----------DMKRKQEHAARLQ-EVQRRLGGWTGPELSAFGELVLEGTFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGPEYTYKGHIFCCNLSVSETPRDPLGFKVSDLTIPKHRHLFQAKNQEEKRLWIHCLQRLFFENHPASIPAKAKQVL---------LENSLHCAPKSKHIPEPPTSPLDSPRPRDAPGFTPGRRNPAPSPRLSGS---RRGRRQSEPAKEAYVIFPQNDKPQVKHAGSEGELHPSSELQP-VSASGLPEDLEDAGPP----TLDPSGTSITEEILELLNQRGLRDSGPATHDIPKFPRDSRVPVESEPLPFQSLPS--RESSEEEEEED--LETDEREPSPLHVLEGLEGSSAAEIPCIPSLTDIPSEVPSLPEIP------EAPCLPCLSDISGVFEVPCLSPTSTVPDIPSLATTPSFPCGSWLPGPLQEAAQPQATRRELLSGSNPGRLSESPSESREGQEDDTEGVSFSAVQREAGTSVQGFPEELEYRSCSEIRSAWQALEQGQLARPGFPEPLLILEDSDLRGGSTSGKTGMPHSERSASRVRELARLYSERIQQMQRAETRASTN------------APRRRPRVLAQPQPSPCPPQEEAEPGALPAFG-HVLVCELAFPLNCTQESVPLGPAVLVQAATPLCIQGDDLSGQNLNVSDLSKQGHLSSNSIPPPVPLPGQS-------NFQNIQVPSTSLLPKQE-PPDVQVPTASTLPDTSQLQSQVPAATPSAGHRNCVEIQVQS----------------TTSLPGQECQAD-----TVALSKQEGHEDSQNPNKAPGAEQRDVSIDQGLAVVGGRPVSPLPVCTSSPDQQIPATTPLPLSTDFPDMEGPGALPLPTQEGRPDCSIPCNPLPSLSQDV---QVPAVIPVSQLQGLTDTRATVPLSSHKQ------------------EDAPECLG-------PEPSLTDTPAPRLLSSLGQQNTTDGPVSAAAVPLTEQGCSQDLQGLITSPVQTTMELPKPRG-LVSRVATSESLDLTPPHSPSLSTRQ---LLGPSAAALSRYLAASYISQSLARRQGPGGEGTVASQGHWSSSAPTSRAPSPPPQPQPPAPPARRLSYATTVSIQVGGGGRLRPAKAQVRLNHPALLAAPHP--GAVGPSQGPGGS----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7P9-1", "uniprot_id": "PKHG2_HUMAN", "id": "Q9H7P9-1", "name": "Pleckstrin homology domain-containing family G member 2", "aln": "-------------------------------------MPEGAQGLSLSKPSPSLGCGRRGE------VCDCGTVCETRTAP-AAPTMASPRGSGSSTSLSTVGSE-GDPAPGPTPACSASRPEP------------LPGPPIRLHLSPVGIPGSARPSRLERVAR----------EIVETERAYVRDLRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYEFSSELLEDLENSSSAGG--IAECFVQRSEDFDIYTLYCMNYPSSLALLRELS-LSPPAALWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGPGTGGREMVEEAIVSMTAVAWYIN-----------DMKRKQEHAARLQ-EVQRRLGGWTGPELSAFGELVLEGAFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGLEYTYKGHIFCCNLSVSESPRDPLGFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFENHPASIPAKAKQVL---------LENSLHCAPKSKPVLEPLTPPLGSPRPRDARSFTPGRRNTAPSPGPSVI---RRGRRQSEPVKDPYVMFPQNAKPGFKHAGSEGELYPP-ESQPPVSGSAPPEDLEDAGPP----TLDPSGTSITEEILELLNQRGLRDPGPSTHDIPKFPGDSQVPGDSETLTFQALPS--RDSSEEEEEEEEGLEMDERGPSPLHVLEGLESSIAAEMPSIPCLTKIP-DVPNLPEIPSRCEIPEGSRLPSLSDISDVFEMPCLPAIPSVPNTPSLSSTPTLSCDSWLQGPLQEPAEAPATRRELFSGSNPGKLGEPPSGGKAGPEEDEEGVSFTDFQPQDVTQHQGFPDELAFRSCSEIRSAWQALEQGQLARPGFPEPLLILEDSDLGGDSGSGKAGAPSSERTASRVRELARLYSERIQQMQRAETRASAN------------APRRRPRVLAQPQPSPCLPQEQAEPGLLPAFG-HVLVCELAFPLTCAQESVPLGPAVWVQAAIPLSKQGGSPDGQGLHVSNLPKQ-DLPGIHVSAATLLPEQG-------GSRHVQAPAATPLPKQEGPLHLQVPALTTFSDQGHPEIQVPATTPLPEHRSHMVIPAPSTAFCPEQGHCADIHVPTTPALPKEICSDFTVSVTTPVPKQEGHLDSESPTNIPLTKQGGSRDVQGPDPVCSQPIQPLSWHGSSLDPQGPGDTLPPLPCHLPDLQIPGTSPLPAHGSHLDHRIPANAPLSLSQELPDTQVPATTPLPLPQVLTDIWVQALPTSPKQ------------------GSLPDIQGPAAAPPLPEPSLTDTQVQKLTPSLEQKSLIDAHVP-AATPLPERGGSLDIQGLSPTPVQTTMVLSKPGGSLASHVARLESSDLTPPHSPPPSSRQ---LLGPNAAALSRYLAASYISQSLARRQGPGGGAPAASRGSWSS-APTSRASSPPPQPQPPPPPARRLSYATTVNIHVGGGGRLRPAKAQVRLNHPALLASTQESMGLHRAQGAPDAPFHM-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZBA1-1", "uniprot_id": "A1ZBA1_DROME", "id": "A1ZBA1-1", "name": "", "aln": "MDIESDSDTSERWEDFFGSSTELAPSLLGIYDTLTNSFAAGGVAAAPTATSHESKASSSGDSTPKRSNSNCSSSSSTGSSTGSCSSVPTSDDQSASYTLASSSTHLGHQEPPAPLVVAGLRDEPDGAQLSRLVQRRSQESQIHGSSSSIASSGSSRRGSNIRILSPNVHRIITHSDIQPVEAVSAEALKQHQQQSQRSPTQGRYIKTGHSGTPPAAGSAPKLKLSHIPLSKITGKLSTQSGSELVSTFDSSNEYLNSVAFAAFEKSKPQDEDRTPTNKSVPGTPFHFDGHPFQGRKLTLPRYDSQQSIKLIEMEQLAATSAQLLHAKPATPGTPATPTPSATKAKEFVCSEPLSPVDIVDTINFDLVAQHMERLTLADPGDLDPRAELIEAVNKTLVNKPLVRSSSAACASTICSSPLLTYARTKSLGAKASTLGGGVPIKLPTAEQLAELEEANKLSAESLDR-LTDIKPKFAARLSELARLNNRPLSSSSICSTSSSSSSGSDQLLNGKLMATSYLASVESLAESENELGDQHHPPAMSVLEKTCLEIVDSERSFVEDLGQVIKGYLQDWKERACLRVDELQILFANIEEIYEFNSMLLQRLINTGRDPGRIARCFIDLRDGFDVYTTYCTSYPEAISLLTKLLQATHTYSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSLRKHCDVKEVVEAHVIMRQVAHNIDQVKRKQEQQSRVKELSGILDGWLGPELTVLGELRQ-----EGLLMEQHNKQRLVLLFATMLIITKQKEDGRLQFKTYISQNNLMLSEHLPGEPTSFYVIPFDEPRHQIKLTARNRDQKRIWTQHIKGVMLEKLDIPMRAKELVYQLGNEEDRTPDRSTWKWSLHSGSNSTPTYLERRNACRRSEIRQRNSKFKRKTVANSSSFDSFNESLEQEEESISQAKPSKPLARNNSLDDTALQKLAAAMRYRKRDAAVKEETKTPVKEPCKCDQDAKQDERIEPCSCILRDQRSRSAKSQSPVFSYKALKERSKSVPRIGGFSLDEEAEREREQDEDSAASLRGSKPDLSERKTKGKGFFEVKQYNHKTMPKKIANLKKQRSSTTKSCSRFYMDLSEFDSSSSTVLKITESTEELRP-------DGEIELAQEAATLDESTQDQYYSPDHETELLSPAEKSKRDAQIVLDLLKNSKEFERIYNKQQKRRESPVSPVSPDISRGPILPPPRPPSRSPPPLELEEQEKKPVEEVDSVSEEPIYETLLRNVHVPYKFSPVLGRAKSSQILKKRSKTAPAASRPESDYVTLVYSPEGVLQRVGEEVVQRDSCSSSTTSTSSNGSGSTLKRDSQSTVINLLMEAAQEHESRPLPKNSVSGSESSLLPRALKSIDNLSMAFG-RSNRPPERRVSDVSEMCRQSVLHRQGSEAVGERMAHVDYADPKALFGLGVLNHSERDSVFSLTSSSSDSMCEQQRKRSGVGATFEYEQQVEDSLENDFRDSAIYSDDNEKRSGDYDVHLRRPSSPPPPPPPLGPRPHQPPQIAPKPSKDQLIQQRSGVIVCQSASRSWVLQQIENFNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *. . : . .* .. *: .:*.: ..* :: :...:.:. ...:* :*:: .:. *. * . :. : ** . *: .:. ** : . *: :* .* . .. *:. :: . :* : . . . . .. .: * : *: .* :.. * . .* :: :: .:: ... * : * *.: : : :. :.*.* : : :::: . * .: * : * . . .: : : ::. :* ** *. : :. ** : .*..... . .. ** * ** :: .: .. : *. : * :.. : : *: .* ** : *. : . .:* .: :.*:* * . * ..: : : .* * : . :. ..*. . . : :.:: : :: * : :. . : :* . : :. . * *.. *: ::*: : .* . : . : .. * :: * . *. .: :* : : : . :* . * . .: . : ::. * *: *. : .. *: .. : .. : * .. :. .. : . . : : :* : :. :** : .: : : .: : :*..*. : * : * . *:: . . * .. : . ..* . .* *.* : ::. * * * * * * * : :* .: . . . :: *. : ::.: . .*. :* . . .* .* . :: . . . * . . :: . :**: . * .: :. . : ::. . : :. :. : . . .. ..... : . : : .*:. .. . . * . * :: *.. * .: *. * *.. . : : . : . .... :.: : * : :. : * .:.. . . ..* . .::: *. . * .: . . *:: . ** :* * :. . : :. .: .:. .. :* . * : .. . : *. . ..... *.. :*:*.:*: ... * . .. ", "identical_positions": 133, "similar_positions": 452, "identity": "8.51%" }, { "cls_id": "homologset.agr.MGI:2141879", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35048-1", "uniprot_id": "3BHS7_RAT", "id": "O35048-1", "name": "3 beta-hydroxysteroid dehydrogenase type 7", "aln": "MADSAQVPALVYLVTGGCGFLGEHIVRMLLEWEPRLRELRVFDLHLSSWLEEL--KTGPVQVTAIQGDVTQAHEVAAAMAGSHVVIHTAGLVDVFGKASPETIHKVNVQGTQNVIDACVQTGTRLLVYTSSMEVVGPNVKGHPFYRGNEDTPYEAIHR-----------------HPYPCSKALAEQLVLEANGR--------------------------------KGLRFGGRLFRAIP-ASVEHGRVYVGNVAWMHILVARELEQRAALMGGQVYFCYDKSPYKSYEDFNMEFLSPCG-LRLIGTHPLLPYWLLVLLTALNALLQWLLRPLVLYTPLLNPYTLAVANTTFTVS-TNKAQRHFGYKPLFSWEESRARTIHWVQAMEGSAW---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQC1-1", "uniprot_id": "3BHS7_MOUSE", "id": "Q9EQC1-1", "name": "3 beta-hydroxysteroid dehydrogenase type 7", "aln": "MADSAQVPTLVYLVTGGCGFLGEHIVRMLLEREPRLRELRVFDLHLSSWLEEL--KAGPVQVTAIQGDVTQAHEVAAAMSGSHVVIHTAGLVDVFGKASPKTIHKVNVQGTQNVIDACVQTGTQYLVYTSSMEVVGPNIKGHPFYRGNEDTPYEAVHS-----------------HPYPCSKALAEQLVLEANGRKVNGGL-PLVTCALRPTGIYGEGHQVMRDFYYQGLRFGGRLFRAVP-ASVEHGRVYVGNVAWMHILVARELEQRAALMGGQVYFCYDKSPYKSYEDFNMEFLSPCG-LRLIGAHPLLPYWLLVLLATLNALLQWLLRPLVLYTPLLNPYTLAMANTTFTVS-TNKAQRHFGYKPLFSWEESRTRTIQWVQAMEGSAR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2F3-1", "uniprot_id": "3BHS7_HUMAN", "id": "Q9H2F3-1", "name": "3 beta-hydroxysteroid dehydrogenase type 7", "aln": "MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEEL--KTGPVRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHR-----------------HPYPCSKALAEWLVLEANGRKVRGGL-PLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIP-ASVEHGRVYVGNVAWMHVLAARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCG-LRLVGARPLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVS-TDKAQRHFGYEPLFSWEDSRTRTILWVQAATGSAQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVE3-1", "uniprot_id": "Q9VVE3_DROME", "id": "Q9VVE3-1", "name": "3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein", "aln": "---MGNKSGEVLLVTGGSGFLGQHLIKQLLERKEELGIKEIRSLDIVPYKNNIGHEETSLLRTYVADIGGDLKALSPIFNGVDGVFHCAASVKIEYPPNYEELERVNVNGTLAVVDLCIQNNVKRLVYTSCTSVCFVPFKGRSTFSAVINSTESKTDTPTLDSSTLWEQDNQFLIPGYASSKLRAENIVLNSNGAPLHNQKEYLATSAMRAPLTYGECDSHFITEIFDFLSTRGWVFPRIAGVGGKQQLVYAGNVAWGHICAYKALKVSDKAVNGLPVFVTDDTGINDVSRFVQKMAVLGERFKVKTSWWYVPHFLFFFLAFLLEVVVRVAYPYTKYRLRYSLRAIASYTSSMLMYNRLRASIHMDYMPLFDPDASAERSAKWYATWWDQRQQAQKLKKSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * *****.****:*::: **: : .* .: . .: .: ::: : .: * : . : : ::. . * . *:* *. *.: .. : :..***:** *:: *:*...: *****. .* **:. : . ::. . . *..** ** :**::** . * * :* :. .. :: **.***** *: . : *: :.* * * : .. . * :: ::: : :*::*:.:*: * :: : * . * . ::* .::: : :*. *:.* ***. : * *: * : .. ", "identical_positions": 77, "similar_positions": 120, "identity": "19.2%" }, { "cls_id": "homologset.agr.MGI:2141881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYH2-1", "uniprot_id": "IN80E_RAT", "id": "Q6AYH2-1", "name": "INO80 complex subunit E", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGPADGEVDYKKKYRNLKRKLKFLIYEH-----------------ECFQEELRKAQRKLLKVSRDKSFLLDRLLQYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPMGG-------------APSPSSLSLPPSSGFPLQTSGAPSPYLSSLASPPY--PPFPSDYLALQLPEPSPLRPKLEKRPR-LPRKLKMAVGPPDCPVGGPLAFPARGSGASVGAALTPLPPPKMPPHTILSTVPQQMFSDAGSGDDALDGDDDLVIDIPE---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z3H0-1", "uniprot_id": "D3Z3H0_MOUSE", "id": "D3Z3H0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGPADGEVDYKKKYRNLKRKLKFLIYEH-----------------ECFQEELRKAQRKLLKVSRDKSFLLDRLLQYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPMGG-------------VPSPSSLSLPPSTGFPLQTSGAPSPYLSSLASPPY--PPFPSDYLALQLPEPSPLRPKLEKRPR-LPRKLKMSVGPPDCPVGGPLAFPARGSGASVGAALTPLPPPKMPPHTILSTVPQQMFSDAGSGDDALDGDDDLVIDIPE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBZ0-1", "uniprot_id": "IN80E_HUMAN", "id": "Q8NBZ0-1", "name": "INO80 complex subunit E", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGPADGEVDYKKKYRNLKRKLKFLIYEH-----------------ECFQEELRKAQRKLLKVSRDKSFLLDRLLQYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGG-------------APSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRY--PPFPSDYLALQLPEPSPLRPKREKRPR-LPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDLVIDIPE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z8D5-1", "uniprot_id": "A1Z8D5_DROME", "id": "A1Z8D5-1", "name": "INO80 complex subunit E N-terminal domain-containing protein", "aln": "--------------------------------------------------------------------------------------MLDGWYCRSLANQEDGAIKDEPPSDDEPAQPARDRVPPISR-----------------------------------------GAAPASSSSVSAGLGAGETDFKERYKNLKKKLKFLIYEN-----------------EYFQDLLHTNQRRLLKVSRDRTFLLDRLLVYEKPAKDSSDSDATDSSDSEPASTSGVAGGSQTSKDAIRRKHKD-------------KGAPGIPGVPPHMPTVGAPRGRRRKILTGMLPANHGIPAIAAKKQLTATVSPSQQPPQLQTAPKDVSPGLSQAEIARQLQERRPTPLELLSPECTSATVPTTMLSDESPSKCYPNESLQHLMEDD-SHSHEVAAEECVPMEYTS---------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0R4IGV0-1", "uniprot_id": "A0A0R4IGV0_DANRE", "id": "A0A0R4IGV0-1", "name": "", "aln": "MHLPRLTVLLISAVLVNGGVVRASSHADLDPGFLQCHDCFFRGSPPQALSDVGLEQRCHRHLTGRPFASLFNTNCQSTVFTALHLSLNNGWGRGEESTEAQEEINDDSHEAIPALYRETSDETPSSSPFLQWDSLTAELIRSSIIAKCSENGGEIYVQNGVGGFNECGGKPMWSALCCAASGGDGSFSFGLVKEGDVKVLSIKALEERIGVTGLFSGGCGEIGHEMEEELASILKKEMNSIETPNSDAQSEEHISKRNTQEAESSESIDEEVNSESSESSLGSDMNIQEDTEEIERSESVLLYILSTIVSLLYAPFSPIVNIATNLPFQLGYVLQEDLAVLASVPVDSFTLVNNLGSGVCSGVSCILNTLYQTGETSVCTMYACLSPLAGSLGLAFQEGFIGTGTLASDAVGIMTGTVGNGFSIIRTVLGSVWDGTVDYLWAVSSEMGHQVSTVGSGIGKLTWRSGKGVGHVLNFGVSIVGGVVENTVDNVLEAFGGSSGESSQLQTPELLTSEVVGE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *. .: .. : *.: *. * :: ::.: .:. .: .. :. :::..*:: .. .. :. : .. : :* : *: : . .: . * . : . . . .. . . : : .. . : .: :. ", "identical_positions": 8, "similar_positions": 70, "identity": "1.54%" }, { "cls_id": "homologset.agr.MGI:2141917", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIS9-1", "uniprot_id": "KPCD2_RAT", "id": "Q5XIS9-1", "name": "Serine/threonine-protein kinase D2", "aln": "MAAAPSHPAGLPCSP---GPGSPPPPGGSDLQS---------------------------LPPLLPQIPAPGSGVSFHIQIGLTREFVLLPAAS-ELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSAS----ATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVRLGSSESLPCTAEELSRSTTDLLPRRPPSSSSSSSSSSFYTGRPIELDKMLMSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEAL------INGDVPME--EAADYSEAD----------KSSLSD-----------------------------ELEDSGVIPGSHAENALHASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANVTYFVGETP---------GGAPGGPS------GQGTEAARGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISSGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMG-ERYITHESDDARWDQFVSER------HGTPA-------------------EGDLGGACLPQDHEMQGLAERISIL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ03-1", "uniprot_id": "KPCD2_MOUSE", "id": "Q8BZ03-1", "name": "Serine/threonine-protein kinase D2", "aln": "MAAAPSHPAGLPGSP---GPGSPPPPGGLDLQS---------------------------PPPLLPQIPAPGSGVSFHIQIGLTREFVLLPAAS-ELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSAS----ATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVRLGSSESLPCTAEELSRSTTDLLPRRPPSSSSSSSSSSFYTGRPIELDKMLMSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEAL------INGDVPME--EAADYSEAD----------KSSISD-----------------------------ELEDSGVIPGSHSESALHASEEEEGEGHKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANVTYFVGETP---------GGAPGGPS------GQGTEAVRGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISSGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMG-ERYITHESDDARWDQFVAER------HGTPA-------------------EGDLGGACLPQDHEMQGLAERISIL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZL6-1", "uniprot_id": "KPCD2_HUMAN", "id": "Q9BZL6-1", "name": "Serine/threonine-protein kinase D2", "aln": "MATAPSYPAGLPGSP---GPGSPPPPGGLELQS---------------------------PPPLLPQIPAPGSGVSFHIQIGLTREFVLLPAAS-ELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDLVEVVLSAS----ATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSSSSASS-YTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEAL------INGDVPME--EATDFSEAD----------KSALMD-----------------------------ESEDSGVIPGSHSENALHASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEMP---------GGTPGGPS------GQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMG-ERYITHESDDARWEQFAAEHPL--PGSGLPT-------------------DRDLGGACPPQDHDMQGLAERISVL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLD4-1", "uniprot_id": "A0A8M9PLD4_DANRE", "id": "A0A8M9PLD4-1", "name": "Serine/threonine-protein kinase", "aln": "MANVSPFMSPGPMSQVFFPPGGPSPPGSVVLQQGTPVSVHASQTPGFPTMDMGVVSGPGGASGMLPGPPAP-AGVSFIIQIGLTRESVLLPQTA-DLAYVKQIACSIVDQKFPECGFYGIYDKILLFKHDTSSNNILQLVKAVSDIQEGDLVEVVLSAA----ATFEDFQIRPHALNVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSTTSLTSSQSLRLSTTESLSSLNSSMTSEEASLIRSHTQMPRTPSEARRFYTGRPVHLDKILMTKVKVPHTFAVHSYTRPTVCQYCKRLLRGLFRQGLQCKDCKFNCHKRCAYKVPNDCLGETLDILSPSTDAEVPMD--YSSEFSDSD----------KSSLID-----------------------------DSDEACSIPGSFSP----DSSQDRSSGDQSSN----IPLMRVVQSVRQTTRRSSTAIKEGWMVHYSNKDTLRKRHYWRLDCKCIILFQNDTTNKYYKEIPLSEILEVRSAGDFSLVPAGTSPHCFEIMTGTMIYFVGEDPNTSSPSSSISGLPVSPSSVVPNSGVGREVAKGWETAIRQALMPVIFQDNPPAEGHTPHRQASVSISVSNSQIQENVDIGMFYQIFADEVLGSGQFGVVYGGKHRKSGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHLGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILAALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIHNAAFMYPPNPWKQISPDATDLINNLLQVKMRKRYSVDKSLSHAYLQDYQTWLDLRELESKLG-ERYITHESDDSRWQQYARDHTLPYPPHLVPP-------------------PPASDDEDGNEDADMQGLTERVSIL--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHC3-1", "uniprot_id": "A0A0B4KHC3_DROME", "id": "A0A0B4KHC3-1", "name": "Serine/threonine-protein kinase", "aln": "---------------------------------------------------------------------MEGPEVTFLFQFGSVRDAVCVPANSLTLKTLKDLACDFINTKIPDSGLTYLSERILLFVHDYSTPNVLHIINSAAEVVDETLVEIVLTASPILYPTSEMPTLKPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNCN-------RSNDATSRRSFTLQAPRSPSGSSQQSLVSTEDSTGRNDSSSSLNIPGRHQRTHSSGSRNGLMV--LRIPHTFMVHTYGIPTVCQLCKKLLKGLFKQGLQCRDCQYNTHKKCMDKVPHDCTGEAQLSQLQIQAGAKERDNFFREEFDDSDGDDGSEYGKYKSAMSSGVNLVAGRPREAPKALTNAHNSPPELVNGGLVDDSSVSGGETSKSSSDGQSEQSQSSTSSSPSANIPLMRIVQSVKHTKKRGGQALKEGWLVHYTSLDKAVKRYYWRLDSKTITLFVSEQGSKYHKELPLAELLSIESHLGD---PRPECNYCFELRLPNLSYFVGQDPQVGAKEEQAVRLPPPDS------GIGSDIAKSWETSIRQAFMHVTN----------------TQCCESEEQVQD---MGQLYQIFPDEVLGSGQFGVVYGGVHKKTQREVAIKVIDKLRFPTKQEAQLKNEVAILQNISHCGVVNLERMFETPERIFVVMEKLKGDMLEMILSHARGRLSERVTKFLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEEEDINDQIQNAAFMYPPNPWKEISSNAIDLINNLLQVKQRKRYTVDKSLLHYWLQDKQTYRDLRNLEAQVGAGRYLTHEADDLRWDCAGDMXPGCEPEAILESTTELISCSANTTTESYRRSPADCAGCHRLSDCGNSPKSEAMSDRALKWMRFHLCRHIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:* :*:* .*: * :* : * :*::**.::: *:*:.*: : ::**** ** :: *:*:::.: .:: : ***:**:*: .* * ::**:*.****:.*:***.******************* ******...*****. :.. :* :*. * :..* . .. . . . . . * . : ::: :::**** :*:* ***** **:**:***:*****:**::* **:* :**:** **: . : ::.::* **:: . : :.*. : ...:.... :.. *****:****::*.::.. :::***:***:. *. **:*****.* * ** .: .:*:**:**:*:* :.. . * :***: . ****: * * * * * : .:.***:****:* * . . *:.*:*: :. .****.*************** *:*: *:**:*************:**:*******.: * *:**** ******::*******:********* :***.**:********* **::** :**************:* **********:************************* *:**************:************:*******:*******..**..**..* ********** ****:***** * :**: **: ***:**.::* **:***:** **: . . .* . :* :* ", "identical_positions": 405, "similar_positions": 209, "identity": "40.02%" }, { "cls_id": "homologset.agr.MGI:2141920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMC1-1", "uniprot_id": "F1LMC1_RAT", "id": "F1LMC1-1", "name": "", "aln": "-------MWHKAVSIRLCSFSREPGRNEEDVGLELGLGG----------------------------------NLECALRPRGGPEPGPPLARPRPCAVCTPLGPAVAAPPTFHRPLR--SLLPHIPDGAKESLRSPPPPAPGLRAEGARPGVARAFLRRASP-------SLPAT---APRERAAH-------AERPLPRPALRGPGAGCGQADDAAALPERRRRREAEVTRRGGPTAMQRSRTAADDAALLLAGLGLRESEPTAGSPGRVRRGPR--------AADETAPVSGRRGKGG-GGPEAAPDVPSRPERGPR----------------ASLAGS-----DGG----SARSSGISLGYDQRHG----------PGPGPPSGGSARSSVSSLGSRGSAGACADLLPPGVGP-------------TPARSPEPA-QFPFPLPSLP----------------------------LPPGREGGPSAAERRLEALTRELERALEARTAR-DYFGICIKCGLGIYGARQACQAMGSLYHTDCFICDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVECYHCEDCGMQLSGEEGRRCYPLEGHLLCRRCHLRRLG----QGPLPSPAVHVTEL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQJ8-1", "uniprot_id": "WTIP_MOUSE", "id": "Q7TQJ8-1", "name": "Wilms tumor protein 1-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRSRTAADDAALLLAGLGLRESEPTAGSPGRVRRGPR--------AVDEAAPASGRRGKGGCGGPEAAPDVPSRPERGPR----------------ASLAGS-----DGG----SARSSGISLGYDQRHG----------PGPGPPSGGSARSSVSSLGSRGSAGACADLLPPGVGP-------------APARSPEPA-QFPFPLPSLP----------------------------LPPGREGGPSAAERRLEALTRELERALEARTAR-DYFGICIKCGLGIYGARQACQAMGSLYHTDCFICDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVDNNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVECYHCEDCGLQLSGEEGRRCYPLEGHLLCRRCHLRRLG----QGPLPSPAVHVTEL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NIX2-1", "uniprot_id": "WTIP_HUMAN", "id": "A6NIX2-1", "name": "Wilms tumor protein 1-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRSRAGADEAALLLAGLALRELEPGCGSPGRGRRGPRP------GPGDEAAPALGRRGKGS-GGPEAGADGLSRGERGPRRAAVPELSAQPAGSPRASLAGS-----DGGGGGGSARSSGISLGYDQRHGSPRSGRSDPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACP-------------APARSPEPAGPAPFPLPALP----------------------------LPPGREGGPSAAERRLEALTRELERALEARTAR-DYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRLQ----PGPLPSPTVHVTEL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZE6-1", "uniprot_id": "WTIP_DANRE", "id": "A8DZE6-1", "name": "Wilms tumor protein 1-interacting protein homolog", "aln": "-----MDEYDEDPGRRASKLMETLSIYDVYQDGMYGEPN----------------------------------PDMEKTKRMNGSSSTPGNKVYSAAPVRSVNGNRASVPLDFCSPQR--EAVYPDPDVYCTKSEVALPCYSGASDRLRRYTHAEVQGHRYST-------GCAYDGLVLGKQVAVS-------GARSNSLCMSSPDGRYTATSPRSSLASSHSSQDQSKHTSPRSSISSPRSSLVSPGQGEGTSVISPRSSYASTASDTSKHSSPRTS----LNSYDCGSKPSSNRTSGISMGYDQRHISPRSSTTSPR----------------SSYSDSR-FTPAGGHDPESAAVHGIPMAS-PRSSICSQPAVAANCVVSPRSSISSHSSRSSRSSRGSMSAYPELQLPMLGPGLPEDALLQDFTEPNGLHNNRVHLQTFPVLEEPQQQNSEVNIGFNYCKAGAGGQRFKLPYQVTPSRDSGPSQAERRLEALTLELEKELEIHMKK-EYFGICVKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTAEKCFVCGHLIMEMILQALGRSYHPGCFRCVICKEGLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVDCYHCEDCGLQLNDEEGHRCYPLEGHLLCHRCHLHRLKTPLAPHPPPSYPLHVTEL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY77-1", "uniprot_id": "AJUBA_DROME", "id": "Q9VY77-1", "name": "LIM domain-containing protein jub", "aln": "MTTQRTQTQARNPGNSDSDYETLMQRLHIGGGGGAGVGGGGGSGGPGDGGVAMRSYQRSPGAIENYLQESQQQQQQHQMQQMQQLHHNQDYKLYERGNIIAASKYATPRPVEQIQHTHNGSAQIYAPTAQILGQRIAPQKHSPVYENLEFYGQFDSNHKRAQPQSPGSRQSAILNGYLLMQPIRAGRFAHTPVPENQGSASLGTTRAAGGPPPPSGRSAALGPTGDLEEHAAPIYENIIPHSGQRAQPQASPATATMYQEMQPTSNSSGSSSTAGLDLNALLASPMHQRSISSNTASSSSLGSPTQRYRNLSLPSHLSPVPTAQSVAKLQQHTPVKSPGGAINVSVNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTVQEPPIITSSLAMGMATAAPPTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGSTAVN-AALKPRRGLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRLALQSSPHARHQEPVCASYQYMG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . : :. . * . . . : . .. . . * ..: . : : : . .. : : :.. .* . * . . * . . .:.: * :.* * .**: *:*::* ** :**. :* : :***** .** : ** *******.****:** * **** ********* :***:**::********:** :************:*:********* :*:* **********:::****.*** :******** : * *.:* : *:******:*:** ** **:**:**..* .:***** *:***: ***:** . . .: .: ", "identical_positions": 155, "similar_positions": 94, "identity": "21.26%" }, { "cls_id": "homologset.agr.MGI:2141921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB91-1", "uniprot_id": "D4AB91_RAT", "id": "D4AB91-1", "name": "Zinc finger protein 575", "aln": "MLGGSVKSEARVSEPNPTSQDPETKEAHQFSCPPVSHQDLP-RPSQ----------PAVSGSVPSGPRRRPPPQRPHRCPDCPKAFSYPSKLATHRLAHGGTRP-----------------------HPCPDCPKAFSYPSKLAAHR-LTHSG---------------------ARPHSCPHC-----------------------------------------PKAFGHRSKLAAHLWTHAPARP--------------------------------------------------------------------------------------------------------------------------YPCPDCPKSFCYPSKLAAHRHTHH-----ATDARPYPCPHCPKAFSFPSKLAAHRLCHDPP--------------------TAPSSQTTGRHRCSSCNQAFGQRRLLLVHQRSHHQPE-----------SQGERE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TXZ1-1", "uniprot_id": "ZN575_MOUSE", "id": "Q3TXZ1-1", "name": "Zinc finger protein 575", "aln": "MLGGSVKSEVRASEPSPTCQDPETKAP---------HQDLP-RPNQ----------PAASGSVPSRPRRRPPPQRPHRCPDCPKAFSYPSKLATHRLAHGGTRP-----------------------HPCPDCPKAFSYPSKLAAHR-LTHSG---------------------ARPHSCPHC-----------------------------------------PKAFGHRSKLAAHLWTHAPARP--------------------------------------------------------------------------------------------------------------------------YPCPDCPKSFCYPSKLAAHRHTHH-----ATDARPYPCPHCPKAFSFPSKLAAHRLCHDPP--------------------TAPSSQATGSHRCSSCNQAFGQRRLLLVHQRSHHQSE-----------GQGERE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XF7-1", "uniprot_id": "ZN575_HUMAN", "id": "Q86XF7-1", "name": "Zinc finger protein 575", "aln": "MLERGAESAAGATDPSPTGKEPVTKEAP--------HQGPPQKPSQSAP------GPTASAGSPPRPRRRPPPQRPHRCPDCDKAFSYPSKLATHRLAHGGARP-----------------------HPCPDCPKAFSYPSKLAAHR-LTHSG---------------------ARPHPCPHC-----------------------------------------PKSFGHRSKLAAHLWTHAPTRP--------------------------------------------------------------------------------------------------------------------------YPCPDCPKSFCYPSKLAAHRHTHH-----ATDARPYPCPHCPKAFSFPSKLAAHRLCHDPP--------------------TAPGSQATAWHRCSSCGQAFGQRRLLLLHQRSHHQVE-----------HKGERD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20385-1", "uniprot_id": "CF2_DROME", "id": "P20385-1", "name": "Chorion transcription factor Cf2", "aln": "-MIKSTTNPQEQRLPRPEDQSPAPPPPPPSS--ATTSTAAPATPTHQVATVIANMDTLKTAFLPNLSMDPNVHVSPHYCPMCHQQFERPQHVADHMQLCHGITLNAQGAIATLDGGHPQAQQHPKLSHPCFNCDEKFGNAVDLDEHHRLAHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQCGSICTTAMLAAGQQGFMEQQEAAVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKNANGGAIVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFRCGYCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYT--CPYCDKRFTQRSALTVHTTKLHPL--------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INE2-1", "uniprot_id": "Q8INE2_DROME", "id": "Q8INE2-1", "name": "C2H2-type domain-containing protein", "aln": "-MNKCPRCNCDATGQNRLVTDSCGHTKCRLCLVADVSDCLECRVARSVD----IQETQETQARTSADKRIIVTDKGYHCTVCNKDFRSRTQQYYHLTCGNDLLKK----------------------FNCKECGRRFATSSHLKYHL-MSHEK---------------------QSKHSCSVC-----------------------------------------HKSFKQPIVLQRHMLTHNQEKHLCPICQKVFRRKSSLASHLAIHSDLG----------------------------------------------------------------------------------------------LQFKCELCSKHFQNKANLNQHLRKHD------KNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRHLRSMHPGCAFASTVEMVTPRSSAQEATTAEERPSQTVRYNSVIQSVGNVEPVMLLQSTPLPSQLPELQMEKGKAVPEHLPLPDVMPEENVQLYRKIILDLDNEEYSSEPSPDAQEPAMQHHQPRVPGQGSSKFSEMHWRKNFKYWYQKEENTK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . : . : *. * : * : * . . * :* . *. . .* * ::*. : *. * : : * . : : . * *.* * ..* * : * . : * * *:* ..* * * .:* * ::. : : * *: :. ", "identical_positions": 31, "similar_positions": 48, "identity": "4.91%" }, { "cls_id": "homologset.agr.MGI:2141942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZT05-1", "uniprot_id": "A0A8I5ZT05_RAT", "id": "A0A8I5ZT05-1", "name": "", "aln": "MEEYEKFCEKALARAQEASLSTDSFLPAQAESVSLIRFHGVAVLSPLLTIEKREKIQQEKQKALDVQTRKQANR--KKALLTRVQEILENVQVRKAPNASDFDQWATETIASNSEVTGLSVPVTVPSDLLSPTEHCTSGKLGKTTGLLPVNNEDQQSPERMG--LPKDSEVFGSLKQCESPGSRWAENGAAPRLSSASSQETVISDDPLLAKEEQEPS------CLAEVTPDPYIISLQNLMKRSKEYVEREQSSWSLRSSLKKSVHETHSDKENDAAKASDCVKEKAPPMPVGRHCGSAIPDKPSLNKSNVLLQGAS-QASSLGTSVLASFLKTDLPVGTGPPTVPDAESDFKVIPTFVTEN-KVKSLIGPYAKLPSPEPSMSPTMHRRHSRSSSACQILINNPVNACELSPKGKEEAVDRIAPAAAET-NESEIVPKPPTDLTGVGSSKVSATKVMSDTIREMVMGKPSQVHQALGNQLGNNVTVEQFAMEGPFIPDGRGMQKVDGTCIAVPKLHELQPTSQCVSSQTLEDACGLKAASVLAKNSCNVQMELNKSYDVKRPSPLLMQTQNSRQQMDTPPVPRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPHILTAGSAEQERERPPERRYPKGSVYGNKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHVQQLSLLIAEQEREQEQLQKEIEEQEKMLKEKAVTTDVS---GLNSALELEWRKRSDPAFLETMLSQVDSLQTSNN--SGFLSSALQYSFGSASEVPLYLRGSLTSGVTKLSVTRPFGRAQPKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAP-LKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMRSPRVALSVATQKSLDRKKFMKVAEMGMANKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSH4-1", "uniprot_id": "CP110_MOUSE", "id": "Q7TSH4-1", "name": "Centriolar coiled-coil protein of 110 kDa", "aln": "MEEYEEFCEKALGRAQEASLSTGSFLPAQAESVSLIRFHGVAVLSPLLTIEKRKKIQEEKQKALDVQSRKQANR--KKALLTRVQEILENVQVRKAPNASDFDQWATETIYSNPEVTDLNVPVRVPNSLPSPTEHCTSVKLEKITGLLPVNNEDQQTPKRVG--LPGDSEVSGSLRQCESPESRQAEDGAALRLSSASPQETIISD--VLGKEEQDPS------CLAEVTPDPYIMSLQNLMKRSKEYVERELSSRSLRNSLKRSVNETHSDRENDAAKASDCVKEKAPPMPIGRHCGSAIPDKPSLNKSNVLLQGAS-QASSMGTAGLASFSKIDLPAGAAPPAAPDAGSDFTVIPTFVTEN-KVKSLKGPYAKLPSPEPSMSPTMHRRHSRSASACQILINNPVNACELSPKGKEEAVDRTAPAAAETTNESETVPKSPTDLTGVCSSNVSATKITSESTREMVVGKPSQRQQALGAHLGNNVTVERSAMEGPFIADDRGAQKVDGTCMAVPKLHELQPSSQCVSSQTLEDVCELKSASLLAKNSCNLQMELNKSYDVKHPSPLLTQTQTSRQQMDTPPVFRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPYIITAGVAEQERDRLLERRYPKGFVHINKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQEQLQKEIEEQEKMLKEKAVTTDVS---DLNSA--LEWRQRTDSALLETMLSQVDSLQTSNN--SGFITSALQYSFGSAGEAPFYLWGSLTSGVTRVSGTRPCGRAQAKWSQVFNPEIHAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAP-LKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSVATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43303-1", "uniprot_id": "CP110_HUMAN", "id": "O43303-1", "name": "Centriolar coiled-coil protein of 110 kDa", "aln": "MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEKQKALDVEARKQVNR--KKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVPATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGID--LARDSEGFNSPKQCDSSNISHVENEAFPKTSSATPQETLISDGPFSVNEQQDLP------LLAEVIPDPYVMSLQNLMKKSKEYIEREQSRRSLRGSINRIVNESHLDKEHDAVEVADCVKEKG--QLTGKHCVSVIPDKPSLNKSNVLLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGSYAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDENTNVPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTVEGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKN-CSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAP-LKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRVPVSGVYAGKIQRKRPNVATI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7A4-1", "uniprot_id": "A0ACD6B7A4_DANRE", "id": "A0ACD6B7A4-1", "name": "", "aln": "MESYEDFIQRCYNSNNDDEAEDEPHTPLTTS--SLIVFHGACILPPVLNEQQRVEMRTLRDTAVSLMTMKRRKRGEEESQSSFADVSISHAEQNTTITDSDIITSAPPALLTCHPLTSTAHDDRSANQLRASPEDQSLDSTQITVLFEGVGHKNDRSHDALDSQTAMMSSGYVTNDNTDLSWMEAAAVRSQLTATGSDIISHAPVDGAILEAEADEVSPLKMADDLTDADEGPYRMSLQNLLKKSQEYRRRQRLLRTQAKALKPSADEHSLSDKENEELPKHIWKTEL------RKVREKKKEKADLIHTDVFNQTNT--HTANHEDISAVFTALPVPAKPLYGSRMKP----------LSVSRSHLAVDDKYANIPTPQFCSSPVRCKKGGGASARVQKALS-----------------------TSDLRSVNDGGLMQTQQITQLELNLSSLKTLISDLESTLTLSHADQSDSLAYNCVKRIVTFG-GAVQQEVIAEDCGIEKQTSPVGVLTDNSNQRTHADGEGSSLIG-----------------------SSYDVDAPSSLWSQLTPEVGGHEG--------------VSRVKRRLLMNEETHCSP---------------------------------------------------------STAVLQMQEDHVTFLMEEERRQQQELLQSLAERYQFLRS--------------------------------------------------VSFPCPSAASRLEDTPTSILASSVCTHTELT--------------------DAQVLCLAAVVKGFLTRRLLRTERVSHIIRTIKDTQMFLQSFQSSVS-CRN------DVMLQERITLQLRSARLELHQLMFISSSCEQMQMIRQDRELRRE---RRTHTHPKGKLSLSDATRKALERKKLLRMQQR------------SADRKRLSPSTEEKWKLVPKICRVSKKKTPTRGAPSHLY-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PDW6-1", "uniprot_id": "Q2PDW6_DROME", "id": "Q2PDW6-1", "name": "", "aln": "-MDATWAMEQLLSAVEMGGSHSEATTPTATTTISIWSAPSEGSGSSSMDPVSFRFHLDGQPILPPLMTSAKKRE------VQLARQMAEALEKRYRLAR----HSAGSDMASRRSVSQLQQTETLIYDSTRGQARPQTLVFGKQLPTIQVDPPTPQP------FVKSIENTSPRRHNRITDRILQFEQSGLGKLLPKVPDKCILRTSPAVAEDQQDQD-----------TKDTTARELGSPLAEPANFQR----SRSFTLEEPSQVLVEHMEREALAVKPSQSLANFE------KQTIESQAKRVNRSARSISSKISHNSYNSNSSAATKSTIATKTTTAGSSCSRRDR-----------EVERIIERALDEHGALEASRKAGVRNYLRGHRERMNQLVIHQE------------------------KERRRMQAEFDHQQRQLIEELCAEIDVSSATENPDSLISQSTSTGDLQR----FSPSPTLPSFSEDIEDFPTMEDKCQIAGPSSARKRLFSPKPSKDSEPQ---------------------------LLSAPSTPRSLPLRNSSLTNSRRS--------------VQVVRRRSQSVGGSLVKT-------------------------------------------------------------ITAADREVKKSPAKPGGGAGRPKSSPGKNSSIIAK-------------------------------------------------------RGSAPPKSASPTKRLGNKYVELKQEER-------------------QWAATRINAGVRGFLVRRLFATEQVQRIVQTIRDTLIFVLNLHLETCGHGLDAEEPANLRLKARLLQQLCSASRTLHLIFFQTNIKDRMEIIARDRQRIKTKLLLKHRRLD-----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : . * : *: . .. : . : : : : .. . . : . : : : . :. .. : . . : :: .. .* . : .. :: . : . . : . :: . .: . .: : .: . : . . . :. : :.. . : . : :: . .: : . . . . * : : . . .. . . . : . . * .* : .. *:** . .:. : . .. :. .:: . : * .. .. . : * .:***.*:*: *:::.:: :*::** *: .:: .. : *: *: ** :* :* ::* . ::*.:: :**: : : ", "identical_positions": 31, "similar_positions": 162, "identity": "3.02%" }, { "cls_id": "homologset.agr.MGI:2141950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CII8-1", "uniprot_id": "SYNE4_MOUSE", "id": "Q8CII8-1", "name": "Nesprin-4", "aln": "MALVPPLGREFPPEPVNCPLAAPRELDVVGGTICPAPEEETSRPEQVQ----ASLGLPEHCMGELKSTESATSPSRLPLASSHEHQDGGKPCEHSDSGLEVLEAEQDSLHLCLLRLNFRLQDLERGLGSWTLAHNRIVQMQALQAELRGAAERVDALLAFGEGLAERSEPRAWASLEQVLRALGTHRDTIFQRLWQLQAQLISYSLVLEKANLLDQDLEVEGDSDGPAAGGVWGPWAPSTFPTPAELEWDPAGDVGGLGPSGQKISRIPGAPCELCGYRGPQSSGQGLED---------LLSLGLGHRKHLAAHHRR-RLRKPQDRKRQVSPSLPDAMLEVDRGVPAPASKRPLTLFFLL--LFLLLVGATLLLPLSGVSCCSHARLARTPYLVLSYVNGLPPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M844-1", "uniprot_id": "SYNE4_RAT", "id": "Q5M844-1", "name": "Nesprin-4", "aln": "MAQFPLLGHGFPPEPVNHPLGGPRGLDVAGPTICPAPEEEPSRPEQVQ----ASLDAPEHFMDEPKSTESATSPSKLPLASSHEHQDGGKPCE------------------------------------------------ALQAELQGAAERVDALLVFGEGLAERSEPRAWTSLEQVLRALGTHRDTIFQRLWQLQAQLISYSLVLEKANLLDQDLEVEGDSDGPAAGGVWGPWAPSIFPTPAELEWDPAGDVGGLGPSGQKISRIPGAPCELCGYRGSQSSGQGFED---------LLSLGLGHRKHLAAHHRR-RLQKPQDKKRQGPPSLPDAMLEVDRGVPAPASRRPLTFLLLL--LFLLLVGATLLLPLSGVPCCSHTRLARTPYLVLSYVNGLPPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N205-1", "uniprot_id": "SYNE4_HUMAN", "id": "Q8N205-1", "name": "Nesprin-4", "aln": "MALSLPLGPRLGSEPLNHPPGAPREADIVGCTVCPASGEESTSPEQAQTLGQDSLGPPEHFQGGPRGNEPAAHPPRWSTPSSYEDPAGGKHCEHPISGLEVLEAEQNSLHLCLLGLGRRLQDLEQGLGHWALAQSGMVQLQALQVDLRGAAERVEALLAFGEGLAQRSEPRAWAALEQILRALGAYRDSIFRRLWQLQAQLVSYSLVFEEANTLDQDLEVEGDSDWPGPGGVWGPWAPSSLPTSTELEWDPAGDIGGLGPLGQKTARTLGVPCELCGQRGPQGRGQGLEEADTSHSRQDMLESGLGHQKRLARHQRHSLLRKPQDKKRQASPHLQDVRLEGNPGAPDPASRQPLTFLLILFLLFLLLVGAMFLLPASGGPCCSHARIPRTPYLVLSYVNGLPPV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** : .**:* * ..** *:.* *:***. **.: ***.* **. *** . :..*.*: *.: . .**:*. *** ** ***.:*:******:***.******:*******::***:*****::**:**:*********:*****:*:** ************ *..********** :**.:*********:***** *** :* *.****** **.*. ***:*: :*. ****:*:** *:*: *:****:*** .* * *. ** : *.* ***::***::::* ******** :*** ** .****:*:.***************:", "identical_positions": 215, "similar_positions": 77, "identity": "53.22%" }, { "cls_id": "homologset.agr.MGI:2141959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT91-1", "uniprot_id": "E9PT91_RAT", "id": "E9PT91-1", "name": "Alpha-1,3-glucosyltransferase", "aln": "MNGWRAPQELAQAQISPLCLGDYGDRARGLNAGALSSQRPSSWRMRTAHGHRLYSPYPHAQRPGSDGTPGMAAFGLAAGSG-HWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHNLPISQWYYEATSEWTLDYPPFFAWFEYALSHIA--KYFDQEMLDIHNLNYYSSRTLLFQRFSVILTDALFVYAVHECCKCIDGKRTGKDLTEKPKFVLSVLLLWNFGLLIVDHIHFQYNGFLSGLLLLSIARLFQKRHIEGAFLFAVLLHFKHIYLYVAPAYGIYLLRSYCFTASKPDGSVRWDSFSIVRVT-ALALIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSALDKALCVTGL--------------------ELKLLDPSQIPRASMTSGLVQQSQHTVLPSVSPSATLICTLIAILPSVFCLW--FKPQGPRGFLRCLVLCALSSFMFGWHVHEKAILLAILPMSLLAVEKAGDATIFLILTTTGHYSLFPLLFTAPELPIKILLMSLFTVYSISSLRT------LFRKEKPLFNWMETLYLLGLGPLEVCCEFLFPFTS---WKLKYPFIPLLLTSVYCAVGITYAWIRL---YASVL------------TGCLVSKTKKH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P8H8-1", "uniprot_id": "ALG8_MOUSE", "id": "Q6P8H8-1", "name": "Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "----------------------------------------------------------------------MAASGSATAGG-HWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHIA--KYFDQEMLNIHNLNYYSSRTLLFQRFSVILTDALFVYAVHECCKCIDGKRTGKDLTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLSGLLLLSIARLFQKRHIEGALLFAVLLHLKHIYLYVAPAYGVYLLRSYCFTASKPDGSVRWSSFSVVRVT-SLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGL--------------------KLKLLDPSQIPRASMTSGLVQQFQHTVLPSVSPLATLICTLIAILPSVFCLW--FKPQGPRGFLRCLVLCALSSFMFGWHVHEKAILLAILPMSLLSVEKAGDATVFLILATTGHYSLFPLLFTAPELPIKILLMLLFTVYSISSLKT------LFRKEKPLFNWMETVYLLGLGPLEVCCEFLLPFTS---WKLKYPFIPLLLTSVYCAVGITYAWTRL---YASVL------------TGSLVSKTKKH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVK2-1", "uniprot_id": "ALG8_HUMAN", "id": "Q9BVK2-1", "name": "Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "----------------------------------------------------------------------MAALTIATGTG-NWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVA--KYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVI-SLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGL--------------------KLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLW--FKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKT------LFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTS---WKVKYPFIPLLLTSVYCAVGITYAWFKL---YVSVL------------IDSAIGKTKKQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3V8-1", "uniprot_id": "ALG8_DROME", "id": "Q9W3V8-1", "name": "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------------------------------------------------------------------------MK-DLFWHLVGIATGLKILLIPAYHSTDFEVHRNWLAITHSLPLNQWYVDATSEWTLDYPPFFAYFEWLLSQVA--KYVDPRMLVVDNLNYESKATVYFQRLSVIVTDLVYVLGVRSCLGSLG---LGRDTQQ--FFAASMLLLLNVGLIFVDHIHFQYNGLLFGILLLSIGSLIRQRFLWSAFAFAVLLNFKHIFLYMAPAFGVYLLRFYCLEQASVVSAVG----AVVKLL-VVGLTPFAVS---FGPFW--QQLPQVLSRLFPFKRGLTHAYWAPNFWALYNAADKLAAGV-----------------------LKVQDGG----ASTTSGLVQEVRHSVLPAITPPVTFALTALFMLPILVKLFRSAKKQSPLVFLRAVVLCGCSSFVFGWHVHEKAILMVLLPLCLLTLVNREDARYAYVLGIAGYFSLFPLLFDADLYIPRYSLYMSYVAMMYGQLYR------IFPGFR-GFHTLEWLYMLGFMAIPLYEHLLSFLLH---LDQRLPFLPLLLTSVYSALGVLYFFGAY---YLYALGISWGKVPIASSTSAAAVKRKRKTK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40351-1", "uniprot_id": "ALG8_YEAST", "id": "P40351-1", "name": "Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-----------------------------------------MKGDRSRQNMAVTKKAKLKKNDEPKKVLKTAATEKGEGSKRYSLWNFWISTLFLKLLLIPDYFSTDFDVHRNWLAITNKLPISEWYYEHTSQWTLDYPPFFAYFEWFLSQFVPKSVRDDGCLDIVEIGKFGLPTIVFQRLTVIFSEILLFVILQIYINTTK---LSERSQS---FVVASSIVLSPGFLIIDHIHFQYNGFLFAILIGSIVAAKNKRYILCAVLYTTAICFKHIFLYLAPCYFVFLLRAYVLNVNNFKFKSYKDFLFLIRWANLLKLATVVVGIFTICFLPFAHQMPQVLSRLFPFSRGLTHAYWAPNFWALYSFMDKILTTVMLKLPYVHTFATKFIKPPLIPQNIKEINERLAANNNGSKGLVQDVFFVILPQIPPKLTFILTIFYQVLAVLPLL--FDPSFKR-FVGSLTLCGLASFLFGWHVHEKAIMLVIIPFTFLVGFDRRLLVPFMLVASAGYVSLYPLLYKGQDFFIKTLYTYVWCIIYFAAFRKTTKISSSVERRIFFLDRLALTYIFSLLPIVTVLQILDEVKWRYSFLQKFEFLGLMIYSVYCSLGIISSWFALSWLYN---------------FDELLWQ------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ** **** *.****:*********:.**:.:** : **:**********:**: **:.. . * * : ::. . *: ***::**. : : . :: .. . * : :: . *::::*********:* .::: ** .:*.: *. ::. : :***:**:**.: ::*** * : . .:: : * . *. : : :*:***:******.*** ************. ** :* : . :.****: . :** :.* *: * : : :. * . . *: .:.**. :**:**********::.::*: :* . :: :*: **:***: . : : . : . :. : *::.: .: .:: . : *: *:: ***.::*: : * . : ", "identical_positions": 146, "similar_positions": 147, "identity": "22.53%" }, { "cls_id": "homologset.agr.MGI:2141969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0D5-1", "uniprot_id": "EFL1_MOUSE", "id": "Q8C0D5-1", "name": "Elongation factor-like GTPase 1", "aln": "MVLSGVDKMIRLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAE-----GHEE-----YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETESQAKPHSEQGEQVYDWSAGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGK--KPLFVQLILENIWSLYDAVLK-KDKEKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCHKLPSPLDMTSERVEKLLCTGSQTFESLPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHAEKLAAA---QGQTSQGPTQDG-----------GALETSPHEDEPRG------------DEPDVASVSRQPVSQEESS-------------------------------------------------------QEAFIAFARVFSGIARRGKKIFVLGPKYSPVDFLQRVPLGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDFVLKSATLCSL-PSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGIHVDSDGLITIPTPNKLATLSVRAIPLPEEVTRILEENSDLIRSMELLTSS-LNEGRN-TQAIHQKTQEKIWEFKGKLEKHLTGRKWRN-TVDQIWSFGPRKCGPNILVSRSEDFQNSVWSGPAGRESKEASR---FRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEQGASDKQHQGQCDLAGEGQGGGKTCHVGDENQEQQDVCSEPFEE-TSQKGDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXJ5-1", "uniprot_id": "D3ZXJ5_RAT", "id": "D3ZXJ5-1", "name": "Elongation factor-like GTPase 1", "aln": "MVLSGLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAE-----GSEE-----YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILGQINALTGTLFTSKVLEERAERETESQAKSHSEQGDQVYDWSTGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGK--KPLFVQLILENIWSLYDAVLK-KDKEKVDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDMTSERVEKLMCTGSQTFESLPLETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHAEKLAAA---QGQAPQGPTQDG-----------GALETSPQEDEPRG------------EEPDMTSVSRQPAPQEESS-------------------------------------------------------QEAFIAFARVFSGVARRGKKIFVLGPKYSPVDFLQRVPQGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDSVLKSATLCSL-PSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGILVDSDGLITIPTPNKLATLSVRAIPLPEEVTRILEENSDLIRSMELLTSS-LNEGRN-TQAIHQKTQEKIWEFKGKLEKHLTGRKWRN-TVDQIWSFGPRKCGPNILVSRSEDFQSSVWSGPAGRESKEASR---FRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEPGASDKQSQGQCDLTGEGQEKSKTCPVGDENQEQQDGYSEPFEE-TSQKGDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z2Z2-1", "uniprot_id": "EFL1_HUMAN", "id": "Q7Z2Z2-1", "name": "Elongation factor-like GTPase 1", "aln": "MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYAT-----GNEE-----YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKIMKGDQAKGK--KPLFVQLILENIWSLYDAVLK-KDKDKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTQEEIAQRRERARQRHAEKLAAA---QGQAPLEPTQDG-----------SAIETCPKGEEPRG------------DEQQVESMTPKPVLQEENN-------------------------------------------------------QESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLRRVPLGFSAPPDGLPQVPHMAYCALENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCSL-PSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLKERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQMKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPEEVTQILEENSDLIRSMEQLTSS-LNEGEN-THMIHQKTQEKIWEFKGKLEQHLTGRRWRN-IVDQIWSFGPRKCGPNILVNKSEDFQNSVWTGPADKASKEASR---YRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLSKFEEQGAS--------DLAKEGQEENETCSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV61-1", "uniprot_id": "Q9VV61_DROME", "id": "Q9VV61-1", "name": "Ribosome assembly protein 1", "aln": "MPVVEGSDLVLLQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSSSISLYYQEAEEMAGNPD-----YLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLRQIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKD--------------NYESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLENVLWGDFYYNSKKKEALPGAQEKAK--KPMFVQFVLENIWSLYDIIAIRKDKDKLPGIAEKLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLPPETLELKESFTSCDAN-SSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQQS---EQAELEKISQGV-----------EQLSTQVVGPEKEE------------SKPE----------EADQN-------------------------------------------------------EFVFIAFARVFSGTLKRGMELFNLSPKHDPRQPTHRKEG----------EAPYASRVTIGDLYMFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSSS-LDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKT----------AEDKDVSKKIAVQQ-------TLNKLGTLKVIAVPLPAEAVELLETHSEFFKELAAIPRNQLLSEKW-TALLASIKVKLIAALKDLQLFGLSTLSPEE-LVNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCEEPMQGVCFAVLEWSIQ-------------------SEGED----------------------------------LNSRGPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFSHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGLFVDEQVVEHAEKQRTLSKNK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53893-1", "uniprot_id": "RIA1_YEAST", "id": "P53893-1", "name": "Ribosome assembly protein 1", "aln": "MPRVESETYKRLQNDPSCIRNICIVAHVDHGKTSLSDSLLASNGIISQRLAGKIRFLDARPDEQLRGITMESSAISLYFRVLRKQEGSDEPLVSEHLVNLIDSPGHIDFSSEVSAASRLCDGAVVLVDVVEGVCSQTVTVLRQCWTEKLKPILVLNKIDRLITELQLTPQEAYIHLSKVIEQVNSVIGSFFANERQLDDLFWREQLEK-----------NENAEYIEKDDSGIYFNPTDNNVIFASAIDGWGFNIGQLAKFYEQKLGAKRENLQKVLWGDFYMDPKTKKIINNKGLKGRSLKPLFTSLILENIWKIYQNIITSRDSEMVEKIAKTLNIKLLARDLRSKDDKQLLRTIMGQWLPVSTAVLLTVIEKLPSPLESQTDRLNTILVSESDTAAMDP----RLLKAMKTCDKE--GPVSAYVSKMLSIPREELPVESKRIASSDELMERSRKAREEALNAAKHAGMVENMAMMDLNDNSKNTSDLYKRAKDTVMTPEVGEQTKPKPSRNNDVFCVVSEPSSALDLEFEYEGEDDSDSQDNFGLDFVPTDIDPNDPLSSMFEYEEEDPLLESIKQISEDVNDEVDDIFDEKEECLVAFARIYSGTLRVGQEISVLGPKYDPK-----------------CPEEHIETAIITHLYLFMGKELVPLDVCPSGNIVGIRGLAGKVLKSGTLIEKGVQGVNLAGVNFHFTPIVRVAVEPANPVEMSKLVRGLKLLDQADPCVHTYVENTGEHILCTAGELHLERCLKDLTERFAGIEITHSEPAIPYRETFLSASDMNPP------------------QNSQLGRGVHELL---------LSQYKITFRTFPLSGKVTDFLSQHQNSIKNILKTSTSSMDPVIESTGSSFLDKKSLLVAFEEVINQEEKSRELLSGFKVKLAGFGPSRVGCNILLSQ-DNLLGSLFEGTPAA-----------FEYSDSIKNGFQLAVSEGPLANEPVQGMCVLVESVHKMSQDE---------------IESIE------------------------------DPRYQQHIVDLSGRLITSTRDAIHEAFLDWSPRIMWAIYSCDIQTSVDVLGKVYAVILQRHGKIISEEMKEGTPFFQIEAHVPVVEAFGLSEDIRKRTSGAAQPQLVFSGFECIDLDPFWVPTTEEELEELGDTADRENIARKHMNAIRRRKGLFIEEKVVENAEKQRTLKKN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 318, "similar_positions": 359, "identity": "25.87%" }, { "cls_id": "homologset.agr.MGI:2141979", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK39-1", "uniprot_id": "CP054_RAT", "id": "Q5BK39-1", "name": "Transmembrane protein C16orf54 homolog", "aln": "MPATPQQPSGHTEGLTEPTSEAAMWVVIPCGPCIPIMLGLASLTAFFIITTAVLAERLFRRPQ-PDPSQRAPTLVWRPGGELWIEPTSSARERSEDWYGSSIPLLMDRAPDPPTPGGTLEGRATAPPAIPTPHPSPSSLVPQTPPEVPAQSTFWRPQTQEESPYATGLVSWVGPEPMAEAGLEVGSPRAWRLRQGSLEPDWSLQPRVTLEQISAFWKREGRTSVGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C708-1", "uniprot_id": "CP054_MOUSE", "id": "Q8C708-1", "name": "Transmembrane protein C16orf54 homolog", "aln": "MPVTPQQPSGHTEGLPEPTAEAAVWVVIPCGPCIPIMLGLASLTAFFIITTAVLAERLFRRPQ-PDPSQRAPTLVWRPGGELWIEPTSSARERSEDWYGSSMPLLMDRAPGPPTPGGTLEGRATAPPATSAPYSSLSSLVPQTPPEVPAQSTFWRPQTQEERPHDTSLVSWVGSEPMPEAGLQVGSPRPWRPRQGSLEPDWGLQPRVTLEQISAFWKREGRTSVGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWD8-1", "uniprot_id": "CP054_HUMAN", "id": "Q6UWD8-1", "name": "Transmembrane protein C16orf54", "aln": "MPLTPEPPSGRVEGP--PAWEAAPWPSLPCGPCIPIMLVLATLAALFILTTAVLAERLFRRALRPDPSHRAPTLVWRPGGELWIEPMGTARERSEDWYGSAVPLLTDRAPEPPTQVGTLEARATAPPAPSAPNSAPSNLGPQTVLEVPARSTFWGPQPWEGRPPATGLVSWAEPEQRPEASVQFGSPQARRQRPGSPDPEWGLQPRVTLEQISAFWKREGRTSVGF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **: ***:.** *: *** * :********** **:*:*:**:************. ****:***************** .:***********::*** **** *** ****.******* .:* .: *.* *** ****:**** **. * * *.****. .* .**.::.***:. * * ** :*:*.************************", "identical_positions": 154, "similar_positions": 36, "identity": "68.14%" }, { "cls_id": "homologset.agr.MGI:2141980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63624-1", "uniprot_id": "SFR19_RAT", "id": "Q63624-1", "name": "Splicing factor, arginine/serine-rich 19", "aln": "MEEEDESRGKTEESGEDRGDGPPDRDPALSPSAFILRAIQQAVGSSLQGDLPNDKDGSRCCGLQWRRCCRSPRSEPRSQESGGADMATVLDTAADSFLVELVSILDPPDTWVPSHLDLQPGESEDVLELVAEVRIGDRDPMPLPVPSLLPRLRAWRTGKTVSPQSHASRPACSRHLLTLGTGDGGPAP---PPAPSSASSSPSPSPSSSSP---------------------------------SPPPPPPPPPPPALPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEE--------GLSQSISRISETLAGIYDDNSLSQDFPGDDSPHREPPPPQTLGAPGTPPQADSTRAEGAPRRRVFVVGPEAEACLEGKVSVEVVTTAGGPALPLPPLPPTDPEIEEGEIVQPEEEPRVAVSLFRAARPRQPPASVATLASVAAPAAPPASAPRAPEGDDFLSLHADSDGE---------GALQVDLGEP---------------PAPPAADARWGGLDLRRKILTQRRERYRQRSASPGP-----------PPARKKARRERQRSG---------------DPAPPDSPT-WEAKKHRSRERKLGSHS--TARRRSRSRSRRRS---RSRSADRRRGS-HRSRSREKRRRRRRSASPPPAASSSSSSRRERHRGKRREGG--KKKKKRSRSRAEKRSGD-LEKLPAPVPP-SGS----DRDSRR--RGAVPPSIQDLTDHDLFAIKRTITVGRPDKTE--PRAPSPAPAVSPKREVLYDSEGLSADERGAKG-DKDRRRSGAASSS----------------------------------------------SSSREKASRRKALDG-------DRGRDRDRSSKKTRPPKDSAPGSGALPKAPPSSGS--SSSSSSCS-------------------------------------------SRKVKLQSKVAVLIREGVSSTTPAK-----------------DSSSSGLGSIGVKFSRDRESRSPFLK--------------PDERAPAEGVKVAPGST-----KPKKTKAKAKAGAKKAKGTKGKTKPSKTRKKVRSGGSSTASGGPGSLKKSKADSCSQAASAKGTEETSWSGEERTTKAPSTPPPKVAPPPP------------------------------------ALTPDSQTVDSSCKTPEVSFLPEEASEDTGVRVGAEEEEEEEE-------------------------EEEEEEE---QQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAARASQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRK---------PPSTLGVTPAPVPTSLGLPPG--PSSYLLPGSLPIGGCGSTP-----------------PTPTGLVPASDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U4C3-1", "uniprot_id": "SFR19_MOUSE", "id": "Q5U4C3-1", "name": "Splicing factor, arginine/serine-rich 19", "aln": "MEEEDESRGKTEESGEDRGDGPPDRDPALSPSAFILRAIQQAVGSSLQGDLPNDKDGARCRGLRWRRCCRSPRSEPRSQESGAADTATVLDTAADSFLVELVSILDPPDTWVPSRLDLQPGESEDMLELVAEVRIGDRDPMPLPVPSLFPRLRAWRTGKTVSPQSHASRPACSRH-LTLGTGDGGPAP---PPAPSSASSSPSPSPSSSSP---------------------------------SPPPPPPPPPPPALPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEE--------GLSQSISRISETLAGIYDDNSLSQDFPGDDSPRREPPPPQTLGAPGTPPQADSTRAEGAPRRRVFVLGPEAEACHEGKVSVEVVT-AGAPALSLPPLPPTDPEIEEGEIVQPEEEPRVAVSLFRAARPRQPPASVATLASVAAPAAPPASAPRAPEGDDFLSLHADSDGE---------GALQVDLGEP---------------PAPPAADARWGGLDLRRKILTQRRERYRQRSASPGP-----------PPARKKARRERQRSG---------------DPAPPDSPS-WEAKKHRSRERKLGSHS--TARRRSRSRSRRRS---RSRSADRRRGG-HRSRSREKRRRRRRSASPPPAASSSSSSRRERHRGKRREGG--KKKKKRSRSRAEKRSGD-LEKLPASVPP-SGS----DRDSRR--RGAVPPSIQDLTDHDLFAIKRTITVGRPDKAE--PRAPSPAPAVSPKREVLYDSEGLSADERGGKS-DKDRRRSGAASSS----------------------------------------------SSSREKGSRRKALDG-------DRGRDRDRSSKKTRPPKDSTPGSGPLPKAPPSSGS--SSSSSSCS-------------------------------------------SRKVKLQSKVAVLIREGVSSTTPAK-----------------DSSSSGLGSIGVKFSRDRESRSPFLK--------------PDERAPAEVAKVAPGSN-----KPKKTKAKAKAGAKKAKGTKGKTKPSKTRKKVRSGGSSTASGGPGSLKKSKADSCSQAASAKGTEETSWSGEERTTKAPSTPPPKVAPPPP------------------------------------ALTPDSQTVDSSCKTPEVSFLPEEASEDTGVRVGAEEEEEEEE-------------------------EEEEEEE---QQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAARISQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRK---------PSSTLGVTPAPVPTSLGLPPG--PSSYLLPGSLPIGGCGSTP-----------------PTPTGLAPASDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7N4-1", "uniprot_id": "SFR19_HUMAN", "id": "Q9H7N4-1", "name": "Splicing factor, arginine/serine-rich 19", "aln": "MEEEDESRGKTEESGEDRGDGPPDRDPTLSPSAFILRAIQQAVGSSLQGDLPNDKDGSRCHGLRWRR-CRSPRSEPRSQESGGTDTATVLDMATDSFLAGLVSVLDPPDTWVPSRLDLRPGESEDMLELVAEVRIGDRDPIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARH-LTLGTGDGGPAP---PPAPSSASSSPSPSPSSSSP---------------------------------SPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVT-AGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPP-APRAPEGDDFLSLHAESDGE---------GALQVDLGEPA--------------PAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAP--APAAAAGPPTRKKSRRERKRSGEAKEAASS---SSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRR--RGAVPPSIQDLTDHDLFAIKRTITVGRLDKSD--PRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSS----------------------------------------------SSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCS-------------------------------------------SRKVKLQSKVAVLIREGVSSTTPAK-----------------DAASAGLGSIGVKFSRDRESRSPFLK--------------PDERAPTEMAKAAPGST-----KPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPP------------------------------------ALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEE-------------------------EEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRK---------PPSSLGMTPAPVPTSLGLPPG--PSSYLLPGSLPLGGCGSTP-----------------PTPTGLAATSDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBI6-1", "uniprot_id": "A0A8M2BBI6_DANRE", "id": "A0A8M2BBI6-1", "name": "", "aln": "MKMGTDGQAEKDEADVVPGESQTEQSPNEEEEVESKTDRRTLGLRCFQGNRETSEDEPSELGAAAVASSEPVFLVPQLSSHPQFLGCDFDVELTAEVKVDDGASLALLTSVTPNLRYQKPGSFLKEHHLFPPSLRKKRVSTDHFFTSDSFPGLCTSVFETPEQTHLPCSFKNSERIIEMAKSPLPSSPSNSPSSPSSAPSSPSSSPSSSSPGGMGTNYQENEDRGHAGDNNVSKGNGDFVSSTSSSLVPSSVPVPPPSSDPSLHASSSFTHPCNDGQSESLENDIYDPFHPTEGEGERDRPSTEDEDEEVDKYDPFEP---------TGSPVSETEEEKRCFDEENEGGSSIISEGNVKAEKEMEIMEPAGTEAGPPDSTETDAPSSVFNNVPLELSTKCSFKDRMREQGK------IKIQGTDSEHSEIEEGEIVGASERVRERVIERR---REVLLPSSSSPSYLQGGVPKPERILRVLEGDGFVSVRADEEWEREPVASVGVGDLRRKLTSRRKEKFRSCPSSASISPPPTSVLPLPSSSFPGSPPLSTDKGRSRKSSKSSKDRDRRKRKEGRGDKEKRKKRKEEKESGEGKRESKAGDHENRSEKEIKDKDREQRSSRSDSRRRKKRRRSTPEHSSRSHSQNASRHNTHSRRSWSSHSEDRHKDKERERERERNHARDRDRDRWRDDRDRERDRESRRRDERRRDREEDTRRSNSRERVNTRRSRDRRDREKEMVRDRDRDRDRRRDSRPVVPPSIQDLNGSDLFAIKRTITVTTTTTTTTVPNSPPRSQRRSHSRSQSSDKHRKRKKKRRRRSEDEERKDEGSRSRSRPTSLSPPRFGYESDHLSDRPEVDMLSLDGEALDSDYPSLEDSPLLSPPPEPPIPSPKIQSGAPKTSRHHPKKKSRSGKTVGQSESTSSSSSHRPKPKIKNLSSVSPPLSASSGNTNSLQPTASSSTTKRERKTGKEKVGKKDAGRSGRSKKLSGGSRKGKLQSKVSVLVREGVSSTTGNSGKLGLDLLGPGGVVSGASGPSVVGGSIAVVFRRDNESRSPFLKPCSETLALPGRGKDPSKTGKQRNILGPPSSTNQSGLKPKKAKPSSATSTSSSASSPTSSLAAKRRRRPGKKPREKGLTVDGSDSKGANSSCSTVGGGWGGVSTEMQPLIGVGSKPSSPPSAPPGPTPSSSSSSSTSSSASILPPSSSPPHTSPLSLPPSRDTRESSPDSQTVDSSCKTPEPSFLLEDGPVQSKASSLTPSKSPASPPGLLTSQMRGDTISQSTTISKPPPPDDQKASPPCSTSAASLSVISHSSATLANDPSSSSSSSVSSSSVNKPPPPPPPPPSAPPLPWSLQTGVDCTAGGVLALTALLFKMEEANIASRAKAQEFIQATSQILSQANQNQSQPHPSSSSSSVSSQVPPPPSHAPPPGPTPAQFILHSSVPLVGCTKTPPSHLHSGLSMGGGCAQTPPPPGLTGPTGGSETGWDSESK-DPDKYLKKLHTQERAVEEVKLAIKPYYQRKDINKDDYKDILRKAVHKICHSRTGEINPVKVSNLVKLYVQRYKYFRKHGRKMDDEEREDRESASMHSSS-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :.:.:.:*:. *:. .::.* . .. : .:**: ..:* . * ... *: .. . . : .. . : * : .*. :**. . .*.. .* . ..* . . :* . .. :.: : :... .:* *.:****.****.******* *. *.. * **. . * :. ..* . : .. . :: ****.** .: . . :.. *:** :: : * ...:*. .* : ::*. ...: .: . : : * . ***.::.. * : * . * . : . ..******** ..*. * : * .. :: : . * *. ***.*:*::*:.: * * *: .* . *.*.:. . .. *: : * *: * *. ::* *:*.:.** : :.: ** ** :: **:*:. * ** . : . ::.:.**:.*.*.:: . .. .*.. :..::*: .:::. **...:* . .: *** ** * .********.. *********** .: *..*. : * .*. *.. .:* :. :::*: .*: * * *.. * ::. .: :.:.**.*.. .:.::..*. **. .. * *.. *:.* *** ******:**:******** . ...* ***.* * **.******** *.: . . .*.*. ****:* .: :.:..: .: .: .:* *:: . . . * .*. .*** ... * .*. . . . **:**. . *.* :************** *** *:.. :: . : .:. . :::: . ..*: :. * ::*: :. **:.*::. *.:. . .. . *. .**:**.* :*****:.****************:********:****.****: : ..*: : .* *.* . *** *:.::* .*:*: ** .** *.*.**. .:. * . .**.: *.**************************:***.*::***************::************: *****:******** .* * . . ... ", "identical_positions": 383, "similar_positions": 411, "identity": "23.97%" }, { "cls_id": "homologset.agr.MGI:2141981", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZM47-1", "uniprot_id": "D3ZM47_RAT", "id": "D3ZM47-1", "name": "", "aln": "-----------MAQRITP----GRASAQPEFYKPGTVSFSDVAVYFSSEEWRCLQPAERALYREVMRETYGLLGSFGIRGAKPALICWVEEETELWGPRAQDPEVAMCKTEVHSDCRQEEKRRKPREETEAIQRTFSTEAGP---KEPCPSFAASPSYLELLSKDPQQGQPTVPLHDTVLKADQRHGCHVCGKSFTRQSKLVEHLYTHTGEKPFQCSECNKCFGRASSLSMHRAIHRRERPHCCPDCGKSFTQRSTLVAHMYTHTGEKPFRCPDCNKSFSWPSSLSTHRAIHRGERPHCCPDCGRAFTHRSGLITHLRVHTGEKPYCCADCGRCFSQSSGLSEHQRVVHSGMTPFSCTHCGRAFARAAYLRCHMRTHTGEKPYSCPDCGRCFRQGSDMAAHRRTHSGERPYPCPQCGRGFPTKSAMTKHQWVHRPGAKGHRDRKASQLSVALGTGQEDPDPPVGFQLYPEIFQECGAWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZQ8-1", "uniprot_id": "E9PZQ8_MOUSE", "id": "E9PZQ8-1", "name": "", "aln": "-----------MAPRMAP----ERASAWPAFLKPGTVSFADVAVYFSPEEWRCLRPAQRTLYREVMRETYGLLASLEVGGDKPALICWVEEESEVWGPGAQEPEVAMCRTEVHSDCRHEKEGKRPREETKATKKILSPEAGP---MEPRPSFASPSCNLELLFKNSQQGHPTVAVHNPILKADQRHGCHVCGKSFAHQSKLVEHLYTHTGEKPFQCPDCDKYFGRASSLSMHRAIHRGERPHQCPDCGKSFTQRSTLVAHMYTHTGEKPFHCPDCNKSFSRPSSLSSHRAIHRGERPHCCSDCGRAFTHRSGLIAHLRVHTGEKPYCCADCGRCFSQSSGLREHQRVVHSGVTPFTCTHCGRAFARAAYLQCHMRTHTGEKPYSCPDCGRCFRQSSDMAAHRRTHSGERPYPCPQCGRRFPTKSAVTKHQWVHRPGAKGHKDKKFSQLSISLDPSQEDPDPPVGFQHYPEIFQECGGWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96H86-1", "uniprot_id": "ZN764_HUMAN", "id": "Q96H86-1", "name": "Zinc finger protein 764", "aln": "-----------MAPPLAPLPPRDPNGAGPEWREPGAVSFADVAVYFCREEWGCLRPAQRALYRDVMRETYGHLSALGIGGNKPALISWVEEEAELWGPAAQDPEVAKCQTQTDPADSRNKKKERQREGTGALEKPDPVAAGSPGLKSPQAPSAGPPYGWEQLSKAPHRGRPSLCAHPPVPRADQRHGCYVCGKSFAWRSTLVEHVYSHTGEKPFHCTDCGKGFGHASSLSKHRAIHR--------------------------------------------------------GERPHRCLECGRAFTQRSALTSHLRVHTGEKPYGCADCGRRFSQSSALYQHR-RVHSGETPFPCPDCGRAFAYPSDLRRHVRTHTGEKPYPCPDCGRCFRQSSEMAAHRRTHSGEKPYPCPQCGRRFGQKSAVAKHQWVHRPGAGGHRGRVAGRLSVTLTPGHGDLDPPVGFQLYPEIFQECG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BV97-3", "uniprot_id": "ZN747_HUMAN", "id": "Q9BV97-3", "name": "Zinc finger protein 747", "aln": "MTDPSLGLTVPMAPPLAPLPPRDPNGAGSEWRKPGAVSFADVAVYFSREEWGCLRPAQRALYRDVMRETYGHLGALGVGGSKPALISWVEEKAELWDPAAQDPEVAKCPTEADP-DSRNKEEERQREGTGALEKPDPVAAGSPGLKAPQAPFAG----LEQLSKARRRSRPRFFAHPPVPRADQRHGCYVCGKSFAWRSTLVEHIYSHRGEKPFHCADCGKGFGHASSLSKHRAIHR--------------------------------------------------------GERPHRCPECGRAFMRRTALTSHLRVHTGEK-------------------------------------------------------------------------------------PYRCPQCGRCFGLKTGMAKHQWVHRPGGEGRRGRRPGGLSVTLTPVRGDLDPPVGFQLYPEIFQECG---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ::* .* . : :**:***:******. *** **:**:*:***:******* *.:: : * *****.****::*:*.* **:**** * *:... :::: .: ** * * :: . **. * .. *. * * * ::.:* . * .: :*******:******: :*.****:*:* *****:*.:*.* **:***** ****** ***** * :***** :*:.* :********* ** ****** * *:.::*********. *::.: . **::* . : * ******* ********* ", "identical_positions": 171, "similar_positions": 78, "identity": "35.7%" }, { "cls_id": "homologset.agr.MGI:2141989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI13-1", "uniprot_id": "GRWD1_RAT", "id": "Q5XI13-1", "name": "Glutamate-rich WD repeat-containing protein 1", "aln": "---------------------------------MAARKG-------------------------------RRHTCETGEPMEAETYDLGSEGPSQVYLPGRGPPLGEGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLSLYLCAGTQAESAQSNRLMMLRMHNLHGTRPPPSEGSDD-EDDEDEEDEEERKPQLELAMVPHYGGINRVRVS---WLGEEPVAGVWSEKGQVEVFALRRLLQVVDDPQALAIFLRDEQARVKPIFSFAGHMG-EGFALDWSPRVP-GRLLTGDCQKNIHLWTPTDGGSWNVDQRPF-VGHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLLSGGDD-GTLKVWDLRQFKSG-----SPVATFKQHVAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDPE--SGETETDPGLAALPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRTISV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810D6-1", "uniprot_id": "GRWD1_MOUSE", "id": "Q810D6-1", "name": "Glutamate-rich WD repeat-containing protein 1", "aln": "---------------------------------MAARKG-------------------------------RSRTCETGEPMEAETCDPGTEGPSQVYLPGRGPPLSEGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLSLYLCAGTQAESAQSNRLMMLRMHNLHGTRPSPSEGSDDDEEDEDEEDEEEQKPQLELAMVPHYGGINRVRVS---WLGEEPVAGVWSEKGQVEVFALRRLLQVVDDPQALAIFLRDEQARIKPIFSFAGHMG-EGFALDWSPRVP-GRLLTGDCQKNVHLWTPTEGGSWNVDQRPF-VGHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTATAHDGDVNVISWSRREPFLLSGGDD-GALKVWDLRQFKSG-----SPVATFKQHMAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDPE--SGETETDPGLAALPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRTISV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ67-1", "uniprot_id": "GRWD1_HUMAN", "id": "Q9BQ67-1", "name": "Glutamate-rich WD repeat-containing protein 1", "aln": "---------------------------------MAARKG-------------------------------RRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVS---WLGEEPVAGVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMG-EGFALDWSPRVT-GRLLTGDCQKNIHLWTPTDGGSWHVDQRPF-VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDD-GALKIWDLRQFKSG-----SPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPE--AGDVEADPGLADLPQQLLFVHQGETELKELHWHPQCPGLLVSTALSGFTIFRTISV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04225-1", "uniprot_id": "RRB1_YEAST", "id": "Q04225-1", "name": "Ribosome assembly protein RRB1", "aln": "MSKRSIEVNEEQDRVVSAKTESHSVPAIPASEEQDAPKNDLEEQLSDEFDSDGEIIEIDGDDEINDEDDLRKKQEEAETLVQKDQSEGNKEKIQELYLPHMSRPLGPDEVLEADPTVYEMLHNVNMPWPCLTLDVIPDTLGSERRNYPQSILLTTATQSSRKKENELMVLALSNLAKTLLK----DDNEGEDDEEDDEDDVDPVIENENIPLRDTTNRLKVSPFAISNQEVLTATMSENGDVYIYNLAPQSKAFSTPG-----YQIPKSAKRPIHTVKNHGNVEGYGLDWSPLIKTGALLSGDCSGQIY-FTQRHTSRWVTDKQPFTVSNNKSIEDIQWSRTESTVFATAGCDGYIRIWDTRSKKHKPAISVKASNTD--VNVISWSDKIGYLLASGDDNGTWGVWDLRQFTPSNADAVQPVAQYDFHKGAITSIAFNPLDESIVAVGSEDNTVTLWDLSVEADDEEIKQQAAETKELQEIPPQLLFVHW-QKEVKDVKWHKQIPGCLVSTGTDGLNVWKTISV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. * : *: :: : : ..* ::*** . ** .* * * .* : *..: ***::*:: * **.:* : * :: * :.**:. :.*.**:* : ** * .*: ::::*:**:: .* :* :* . **::** .:* ::.. **:*:* :: * :... * : :: :**.:. .* . **:.***** : * **:***. ::: :* . . * .*::** *.:.:*:**:*** **.****:...*. ***** *: *..: ..*: * ******* : :**:.*** *: :******... .*** :. * ..:**: ::* *..:.*... *: :* ***:** * * :. * :* ****** :.::*:::** * ** *:**. .*:.:::****", "identical_positions": 155, "similar_positions": 153, "identity": "29.58%" }, { "cls_id": "homologset.agr.MGI:2141990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63035-1", "uniprot_id": "NLRP6_RAT", "id": "Q63035-1", "name": "NACHT, LRR and PYD domains-containing protein 6", "aln": "MDAAGASCSSSE---AVARELLLAALQDLSQEQLKRFRHKLRDAPLDGRSIPWGRLEHSDAVDLTDKLIEFYAPEPAVDVTRKILKKADIRDVSLRLKEQQLQRLGSSS-ALLTVSEYKKKYREHVLRQHAKVKERN---ARSVKINKRFTK--LLIAPGSGAGEDELLGTSGE-----PEPERARRSDTHTFNRLFRGNDDEGPRPLTVVLQGPAGIGKTMAAKKILYDWAGGKLYHSQVDFAFFMPCGELLERPGTRSLADLILEQCPDRTAPVRRILAQP-HRLLFILDGADELPTLAA--PEATPCRDPFEATSGLRVLSGLLSQELLPSARLLVTSRNATLGRLQGRLCSP-QCAEVRGFSDKDKKKYFFKFFRDERKAERAYRFVKENETLYALCFVPFVCWIVCTVLLQQMELGRDLSRTSKTTTSVYLLFITSMLKSAGTN-GPRVQGELRMLCRLAREGILK-HQAQFSEKDLERLKLQGSQVQTMFLSKKELPGVLETVVTYQFIDQSFQEFLAALSYLLDAEG---------APGNSAGSVQMLVNSDAGLRG-----HLALTTRFLFGLLSTERIRDIGNHFGCVVPGRVKQDTLRWVQGQSQ---PKVATVGAEKKDELKDEEAEEEEEEEEEEEEE------LNFGLELLYCL------------YETQEDDFVRQALSSLPEMVLERVRLTRMDLEVLSYCVQCCPDGQALRLVS--------CGLVAAKEKKKK--KKSFMNR-------LKG---SQSTGKQPPASLLRPLCEAMITQQCGLSILTLSHCKLPDAVCRDLSEALKVAPSLRELGLLQNR--LTEAGLRLLSQGLAWPKCKVQT-----------------------LRIQMPGLQEVIHYLVIVLQQS-PVLTTLDLSG--------CQLPGTVVEP----LCSALKHPKCGLKTLSLTSVELTENPLRELQAVKTLKPDLAIIHSKLGTHPQPLKG---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WS2-1", "uniprot_id": "NLRP6_MOUSE", "id": "Q91WS2-1", "name": "NACHT, LRR and PYD domains-containing protein 6", "aln": "MDAAGASCSSVD---AVARELLMATLEELSQEQLKRFRHKLRDAPLDGRSIPWGRLERSDAVDLVDKLIEFYEPVPAVEMTRQVLKRSDIRDVASRLKQQQLQKLGPTS-VLLSVSAFKKKYREHVLRQHAKVKERN---ARSVKINKRFTK--LLIAPGTGAVEDELLGPLGE-----PEPERARRSDTHTFNRLFRGNDEESSQPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYHSQVDFAFFMPCGELLERPGKRSLADLVLDQCPDRAWPVKRILAQP-NRLLFILDGADELPTLPS--SEATPCKDPLEATSGLRVLSGLLSQELLPGARLLVTTRHAATGRLQGRLCSP-QCAEIRGFSDKDKKKYFFKFFRDERKAERAYRFVKENETLFALCFVPFVCWIVCTVLQQQLELGRDLSRTSKTTTSVYLLFITSMLKSAGTN-GPRVQGELRTLCRLAREGILDHHKAQFSEEDLEKLKLRGSQVQTIFLNKKEIPGVLKTEVTYQFIDQSFQEFLAALSYLLEAER---------TPGTPAGGVQKLLNSDAELRG-----HLALTTRFLFGLLNTEGLRDIGNHFGCVVPDHVKKDTLRWVQGQSH---PKGPPVGAKKTAELED---IEDAEEEEEEEED------LNFGLELLYCL------------YETQEEDFVRQALSSLPEIVLERVRLTRMDLEVLNYCVQCCPDGQALRLVS--------CGLVAAKEKKKK--KKSLVKR-------LKG---SQSTKKQPPVSLLRPLCETMTTPKCHLSVLILSHCRLPDAVCRDLSEALKVAPALRELGLLQSR--LTNTGLRLLCEGLAWPKCQVKT-----------------------LRMQLPDLQEVINYLVIVLQQS-PVLTTLDLSG--------CQLPGVIVEP----LCAALKHPKCSLKTLSLTSVELSENSLRDLQAVKTSKPDLSIIYSK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59044-1", "uniprot_id": "NLRP6_HUMAN", "id": "P59044-1", "name": "NACHT, LRR and PYD domains-containing protein 6", "aln": "MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERN---ARSVKITKRFTK--LLIAPES-AAPEEAMGPAEE-----PEPGRARRSDTHTFNRLFR-RDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQP-QRLLFILDGADELPALGG--PEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSP-QCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLG-RRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGG---------VPRTAAGGVGTLLRGDAQPHS-----HLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQG-CPGVAPEVTEGAKGLED----TEEPEEEEEGEE------PNYPLELLYCL------------YETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLIS--------CRLVAAQEKKKKSLGKRLQAS-------LGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNR--LSEAGLRMLSEGLAWPQCRVQT-----------------------VRVQLPDPQRGLQYLVGMLRQS-PALTTLDLSG--------CQLPAPMVTY----LCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HUA8-1", "uniprot_id": "A0AC58HUA8_DANRE", "id": "A0AC58HUA8-1", "name": "", "aln": "MDQDSE------------RAQFVDAHWKTLVQRVIMVMAIADELQSDGMLEWEPYCKIKAAVTNQQKMRELYEVLQSGGDQ----VKSAFYSSLEKHEPYLLGDLGSIKLMGESLADCLNKYKMWIQKEYEYVTEYNSLPGENVLLSERFTQPLIIMRHRERREREEEMCSVGESFQQLLVSRNNADKDSSILDALFG-ADSKGISPNSVILQGNSGNGKSFTAQKIMLDWASGKLCKVEFDCLFHLKCKEVNHVSGEQSLTELLSYNSNLTSEQISRILQKSSEKVLILIDGFDELRFSFSDFSDHLKLKDLSEKAPREASLKVLLMGHILSKTSLLVTTRSTATNTLDSLLKHPKRFTEIMGFSEREVKEYFQKFFQDEELFIKAYEYVRSNETLITACSIPVICWIICTVLRERFSEGSDLTSGLETTTSIYVDFVCTLLEHHSQGLSQPVPTLLRSLGQLAERGMLD-TQVLFEEKSVDEMVSASPFLCKFLFKRR-----IRKETMFSFMHLSFQEFFTALYYISQEEREFLDKLTERFHSQTQSYLSLYLDKDFPLKYGCPEPHFLPVVQFLCGLSNSEVSRSLQEMYNLSVPSFVQPQLREWILDMSKSGVYSYLPFILHCLYELHEKEFVQKAMEAWLELDMSWDPLSRTDCWALLYCLDCCPHFRSLKLNFAASELKMLQDVLCRTPKLGLTVQNVSDTDVTVLLSALGEGKQLGELKLNSSCLSDQSVQQVLKALHKQKKVGGLQISVKSITADTALILTDFLQSCSKAEWEEISGSLSTSDVESLCSSLRLFSFEGKLVVNVVR-LCLSIQNQPSLSEIILNCPRSEASNIDIKSFTESFHNINCIAEESVDFDRNLHALLTLLTSMSGLSALNLSVPFLTETWASRVLFLVESSPKLTVINFHAGSWCSDGVKWLPGLLLEEGIKLLKESAKRPECIVNIRGFRCSKSSERCSRHTEHIDQLSCNQRVTIQFCGDQCTEDIKLKLVLPDEN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :: : . ::: . : ** : ** ::: ::* : :: . : : * ** . ::: :**: : : : *.* * ...* :.:***: ::: :* : . * . . .*: :: ** *.:. * :*:*** :* **:::*:**: ***.*** : :.* *.: * *: . .* :**::*: :. : ::* :. .::*:::** *** . .: * * :. * ** :*. : ****:* :: . *:. * * : :*: ***::: *:** *:*:**. :**.:*:.**** : * :*.:***:**** :::. * **: :****:*: *: ::*. . : ** * :**..*:* :. * *:.::.: .. : .:::.:: :.. . :.*:. *****::** *: : . . : : * : *: ..:** ** .:* *.: . :. *. *: : .*: . .: . . *.: . * * : . ***** : :.* ::::.*. *:: * .. *: ** .: *:* * :: * .*:** : * *. * .: .* : * * . :* * * *. ::: *:* *: * * :: .:: : :.: :* .: :.:.:* . * .* :* * **.::: . **. :: * :: * :: .: . : :*. :. : :. . : : ", "identical_positions": 188, "similar_positions": 281, "identity": "18.74%" }, { "cls_id": "homologset.agr.MGI:2142008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q9M8-1", "uniprot_id": "PWP2B_MOUSE", "id": "E9Q9M8-1", "name": "PWWP domain-containing protein 2B", "aln": "-----MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLSPSTLLPLADNSSAVSCHGQAPEEGTGEVMQLETGPLHPHHKDPEKDQPPKTAVSEPPPPLIPPVPAGNLPPFPPYFEGAPFPHPLWLRNTYQQWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTVSPQEASPSPLNTPKPRRRLGS----GPDSEHRKPEEPEDSAVIATAAPRRS----------KREKREEDRVA-GERVPRSPVIKISYSTPQGKGEVVKIPSRVHGSVEPFCPQQSLQN--GSQDSEVSRDVEPRGGGDRPPSGSSASIPKLKLTRPVPPISDLPPPKIRLKPHRLGDGEHEPLYRAELVEELNGCPRGPLVSSPALFADGSSHGLEDLSSGSSGEDDDLKRFPQGKHGRDGLAFLVDCPGRRTDCTSESVCS-TDSLDELKSSGSEVTSPDTGDLSSGDSASVPSSSADTRQTVPPLTVRLHTQSVSRCVTEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDG--EPSWQEAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANATQHVAPEIRELLTQFEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FFV6-1", "uniprot_id": "F7FFV6_RAT", "id": "F7FFV6-1", "name": "", "aln": "-----MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLSPSTLLPLADNSSAISCHGQVPEEGTGEVMQLETGPLPPHHQDPEKDQPPKTAVPEPPPPLIPPVPAGNLPPFPPYFEGAPFPHPLWLRNTYQQWVPQPPPRAIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTVSPQDASPGPLNTPKPRRRLGS----GPDSEYRKPEEPEDSAVIAMAAPRRN----------KREKREEDRVA-GERIPRSPVIKISYSTPQGKGEVVKIPSRVHGSVEPFCPQQSLQN--GSQDSEVSRDGETKGGGDRPSSGLSASIPKLKLTRPVPPVSDLPPPKIRLKPHRLGNGEHEPLYRAELVEELNGCPRGPLASSPALFADGSTHGLEDLSSGSSGEDDDLKRFPQGKHGRDGLAFLVDCPGRRADCTSESVCSSTDSLDELKSSGSEVTSPDTGDLSSGDSASVPSSSADTRQTVPPLTVRLHTQSVSQCVTEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDG--EPSWQEAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANATQHVAPEIRELLTQFEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NUJ5-1", "uniprot_id": "PWP2B_HUMAN", "id": "Q6NUJ5-1", "name": "PWWP domain-containing protein 2B", "aln": "-----MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARG----VQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGS----GPDRELRKPEEPENGEPTAAATARRS----------KRERREEDRAP-AEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDD-GSQDPEVL-DRESR---DRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRD---SSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACS-SDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSECITEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDG--EPSWREAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANAARHVAPEIRELLTQFET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IGL9-1", "uniprot_id": "A0A0R4IGL9_DANRE", "id": "A0A0R4IGL9-1", "name": "", "aln": "MQASPEELRAGSRLPVTVEQILNDTLVVTLRYREKSFTGILLDCSRKTGLFCLPDVVGKTEEPLILRPDCEVLSEESSSEPVSQPTQRP-----------KDENTEPEESPAPVPIPLQPG-QHTYPPYFEGAPFPQPIWVRHTYNQWVPQPPPRPIKRKKR---RSRDAGRLAISTIRLRPRQVLCEKCKNTLNSDEDSKDGPTLPKTSRKENSPHAEDDNTKTTSAKRKDDGEHNNRESKRREDSTVYDGKRFRKDKKEEEKFPSGDVIPHSPVIKISYSTPQGKGEVMKIPSRVHGSVKPFCPKQLLQNGHGDRDSSKETPKKLQPPMDAIRTGLTISIPKLKLPK--LPSPDAQSPKIRLRSRAEG-AEQMSVYEAELVDGARRRSPRVPNSGLPQSEDAEDKNSLELWSGSCGG-------EVERHG--DLTLLINFRKRKADSSSLSVCS-SDSLDESKSFSSDGTSPELCDLAPGDDISVSSSSQGEGKTVPPLTVRLHTRSMSKCVTEDGHAVTVGDVVWGKIHGFPWWPARILSISGTRREDGEVDAPWPEAKVSWFGSPTTSELSVAKLSPFREFFRSRFNRKKKGMYRRAIMEAAKAVGHMGAEITSLLAHCET", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***.**** ***::*.:****: *:**:******::*:*** *. . . ... *.. * * . : :* *.*.*: *: .* .:**********:*:*:*.**: ********.***.:* *.**.*** :****************.*:.. : * . *:. *: .* . : : ..:. ::. : **. :::::**:: . .: :*:*****************:*********::** *:* *: *.:*.. : : * . : *******.: . .* .*****:.: * .*: .:*.**** . *. . *. . :* ***.* :* .*::*:. ::*.:* *.** :***** :* .*: *..: **:.*.. *..* * :***********:*:*.*:****::*:***:**************:*.** ::*** :..* ************* **::***** ***: ***********:** ***:*. *:..** .**:: * ", "identical_positions": 270, "similar_positions": 159, "identity": "43.2%" }, { "cls_id": "homologset.agr.MGI:2142022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYR5-1", "uniprot_id": "CLRN3_RAT", "id": "Q6AYR5-1", "name": "Clarin-3", "aln": "MPTTQKTLMFLSGFLTSLGSVVVICSILGTQAWITSKIFFTDTISNGTIAITYGLFRGTSSQDLNEGLQELDKNFEVLGILSNSSQKSLHVVVIILLILSLAASLLSSMFTFYNSISNPYQTFLGPMGVYTWNGLSASFVFLTMVLFVGNVDSNHLSEKLSQTLYPDAINKKTTHTYGYSFWLILLVILLNIVTVVIIIFYQKARYHQKQEQRKPVEYAPRDGILF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHH8-1", "uniprot_id": "CLRN3_MOUSE", "id": "Q8BHH8-1", "name": "Clarin-3", "aln": "MPTTQKTLMFLSGFLTSLGSVVVICSILATQAWITSRIFFTDAISNGTIVITYGLFRGTSAQELNEGLQDLDKNFEVLGILDNSSQKSLHLVVILLLILSLAASVLSSVFTFYNSISNPYQTFLGPMGVYTWNGLSASFVFLAMVLFVGNAESNHLSDKLSQKLYPDTTNKRTTHTYGYSFWLTLHVIFLNIVTAVIIIFYQKARYRQKQEQRKPVEYAPRDGILF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCR9-1", "uniprot_id": "CLRN3_HUMAN", "id": "Q8NCR9-1", "name": "Clarin-3", "aln": "MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSASNGSIFITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIFYQKARYQRKQEQRKPMEYAPRDGILF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*******.*:*****.:******.******* * . *: ***:* ******** *:::*..** : .*:* ** **.*****:** *.*::*:*** :*:*** ***************** ********.*****::*:***.*.:**:**::* * *** : .* ***:******* * **:*****..**********::*******:**********", "identical_positions": 161, "similar_positions": 44, "identity": "71.24%" }, { "cls_id": "homologset.agr.MGI:2142037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9E2-1", "uniprot_id": "G3V9E2_RAT", "id": "G3V9E2-1", "name": "Probable RNA/DNA demethylase ALKBH6", "aln": "MEEQDARIPALEPFRVEQAPPLIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPR-QPDDDVPPEQPRPPQQPITSLLVEPRSLLVLRGTAYTRLLHGITATRVDELDSTSLPPNAAACQSALPGARLVR-GTRVSLTIRRVPRVLRASLLLSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2U2-1", "uniprot_id": "ALKB6_MOUSE", "id": "Q8K2U2-1", "name": "Probable RNA/DNA demethylase ALKBH6", "aln": "MEEQDARVPALEPFRVEQAPPLIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPR-QPDDDVPMEQPRPPQRPITSLLVEPRSLLVLRGTAYTRLLHGISATRVDELDATSLPPNATACKSALPGAHLVR-GTRVSLTIRRVPRVLRASLLLSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KRA9-1", "uniprot_id": "ALKB6_HUMAN", "id": "Q3KRA9-1", "name": "Probable RNA/DNA demethylase ALKBH6", "aln": "MEEQDARVPALEPFRVEQAPPVIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSNLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPR-RPEDDDPTEQPRPPPRPTTSLLLEPRSLLVLRGPAYTRLLHGIAAARVDALDAASSPPNAAACPSARPGACLVR-GTRVSLTIRRVPRVLRAGLLLGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQE9-1", "uniprot_id": "ALKB6_DANRE", "id": "Q6IQE9-1", "name": "Probable RNA/DNA demethylase ALKBH6", "aln": "MANLCKRVVDLEKYIVKEAPPTVYYIPDFISEAEEEFLLQQVYRAPKPKWTQLSGRRLQNWGGLPNPKGMLAEKLPDWLLEYTEKISALGAFAGKTANHVLVNEYKPGEGIMPHEDGPLYHPTVTTITVGSHTLLDFYRPVCQAEPDAPQTEE---SRYMLSLLVQRKSLLILQDDMYKCYLHGIRGVCEDVLSEHVVN---ISSTGAQVGDTLPR-STRVSLTIRHVPKIIRANLFLGKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKU5-1", "uniprot_id": "Q9VKU5_DROME", "id": "Q9VKU5-1", "name": "Fe2OG dioxygenase domain-containing protein", "aln": "--------MDFTGFEVRKCPPTVMYIPNFITSEEEQRILSHIERTPKPRWTQLLNRRLVNYGGVPHPNGMIAEEIPEWLQTYVDKVNNLGVFESQNANHVLVNEYLPGQGILPHTDGPLFHPIISTISTGAHTVLEFVKREDTTTETEAGDQT--TREVLFKLLLEPRSLLILKDTLYTDYLHAISETSEDVLCDRISN-YDLCENTYKIGDHLVRRSPRISLTIRNVPKTSKMKLKFC--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.:.** : *:*:**:. **: :* :: .:***:**** .*:* *:**:*:*.**:.*.:* ** *.:*:. *. * . *******:* **:**:** ****::* ::**: *:**:*:* . . . : . .**:: :***:*:. *. **.* . * * . * * * ..*:*****.**: : * : ", "identical_positions": 84, "similar_positions": 67, "identity": "34.85%" }, { "cls_id": "homologset.agr.MGI:2142048", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U319-1", "uniprot_id": "BRE1B_MOUSE", "id": "Q3U319-1", "name": "E3 ubiquitin-protein ligase BRE1B", "aln": "MSGLSNKRAAGDGGSGPPEKKMNREEKTTTTLIEPIRLGGISSTEEMDSKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQRELSS-GTEVPGCQEGLTRDVIPRPDPGTSDLREPLPVQFRAP-LSEPALAFVVALGASSCEEVELQLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARVRTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSG------------SSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLASKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCIPTLSHPDDPGLNALAPGKEDSGPGPGGTPDCKKEMALLAGATS---ATSSIKKEELVSSEDDAQALTPV-------TQGLPSRGREPEARPKRELREREGPSLGPPPAASTLSRADREKAKVEEAKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATK-----------------------QEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVY-ADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CJB9-1", "uniprot_id": "BRE1B_RAT", "id": "Q8CJB9-1", "name": "E3 ubiquitin-protein ligase BRE1B", "aln": "MSGLSNKRAAGDGGSGPPEKKLNREEKTTTTLIEPIRLGGISSTEEMDSKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQRELSSSGTEVPGCQEGLTRDVIPRTDPGTSDLREPLPMQFRAP-LSEPALAFVVALGASSCEEVELQLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARARTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSG------------SSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLASKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCGPNLSHPDDSGLNALAPGKEDSGPGPGGTPDSKKELALVAGATS---VASSVKKEELVSSEDDAQALAPG-------TQGLPSRGREPEARPKRELREREGPSLGPPPAASTLSRADREKAKAEEARRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRDLEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATK-----------------------QEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVY-ADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75150-1", "uniprot_id": "BRE1B_HUMAN", "id": "O75150-1", "name": "E3 ubiquitin-protein ligase BRE1B", "aln": "MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSS-APEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPP-LSEPALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSG------------SSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTT---TTTSVKKEELVPSEEDFQGITPG-------AQGPSSRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATK-----------------------QEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVY-ADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRP9-1", "uniprot_id": "BRE1_DROME", "id": "Q9VRP9-1", "name": "E3 ubiquitin-protein ligase Bre1", "aln": "MSKRSADDATG--SSCLVAAAAAGQPPIKKVHFEPHLIGPVSTLEEMDIKVLEFQNKKLAQRIEQRMRTEAELRHRIEQLEKRQTQDDAVLNVVNRYWNQLNEDIRVLLQRFDAET---ADELENRNENEVTTSFLAQLSTWDKEELDEKLANRVQVSKRAVAKIVQVIDRLMQRNEKITHVLKGDSLASAGSGSGAGAGGEEEQQQASGDAETTTSSAGVHALEETLKQTHIEIMSENHKLQNLNTSLHEKFHTMSLKMKEYQDAHTAKETENAELKNQIDELQYDLEKIHCRNDKLENHLAEAIEKLKAYHQIYGDPNKSTNSAKTPTTTGSGGATTSVNSQLLEELQKELEEYRELANNRLQELDKLHATHRETLKEVEKLKMDIRQLPESVIVETTEYKCLQSQFSVLYNESMQIKTMLDETRNQLQTSKNQHLRQIEVMESEELIAQKKVRSEMIQMEDVLALIRKEYETLRIEFEQNMAANEQTAPINREMRHLITSLQNHNGQLKGEVQRYKRKYKDTSTDNLKLRQELADALATLEGNKLQAATGAAGEEIKQENSTGVKEENSNNVSASGQTNQTNSGNDTNVAIKEENHISAEDEADDEASGKDVKDGIKQEKLSSGDAAAAEKKDSPGPGNSTSSATNSVPVKNEKDSKDGVKGKDVKAVESETVRDLKAQLKKALNDQKEMKLLLDMYKGVSKDQRDKVQLMATEKKLRSEIEELRQQLKKLQESKREERKKLADEEALRKIKQLEEQKYELQKQMANHKPTDNSWGSGAPGTANYTRPFVGSHEEEALLNEMEVTGQAFEDMQEQNSRLIQQLREKDDANFKLMSERIKANQLHKLLREEKTVLEDQMATATTQIEAMHIVLRKLEEKERSLQATVASIEKELMLRQQAMEMHKRKAIESAQSAADLKLHLEKYHAQMKEAQQVVAEKTSSLEAEAYKTKRLQEELAQFKRKAERMKKMEMSGTTIDEVMIEEIREYKETLTCPSCKVKRKDAVLSKCFHVFCYDCLRTRYETRQRKCPKCNCAFGANDYHRLYLQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07457-1", "uniprot_id": "BRE1_YEAST", "id": "Q07457-1", "name": "E3 ubiquitin-protein ligase BRE1", "aln": "---------------------MTAEPATKKIKLELSDP----SEPLTQSDVIAFQKEALFRCINRRRVDFEALRKQYELSRRECIDVSRKLANIMALIVTLARFIETFCTDANEKQ---------------LCREIAQGDE----------------------------TLIVQRSDSFMKLLTKYGKPNTTDSNTNSNASDHIQELTTELKN--------------LRKSKEELFYENSQLTEEISALKEYYTNIIRKY-DRDESFTIKRVFKEDKTDAVKELREDEKESNENNIKSGNKDSSAIN----------------------------GDNTSKKSEKGDELVQAEDERKEDAENEKLELDLKFSDLRAEINS--------------------------------------------------LSSTIKDLENIRRENEEELIKTRSEVSNLKKQQ--IAAADQDPDFKSYDHESLLAKIQHLTEQNAELSEINSSFLSKFQVLAKEKEIYTKKVREEFQKSLDSLVEMN-------------------------------------------------------------------------------------------------------------------SSLEKDVVRIRTARDDLLSKIAILEAEKSKTEVLSDLQHAIDILKEQWTKIDQRSND-TKSSSTQDALIKEIQDLEKGFRELSDLTHKKYSEIINHESVISKLTVEKTKADQKYFAAMRS-------------------------KDSILIEIKTLSKSLSKSNE----LILQLKDSD----RLLQQKIGN------LHKQLDLSQNNERRLIDSSKTETLKIIDLNNTSTKLKRSLEKLQEESNKSIADMTHLETKLNDTEIELKHFKQKASHLESKCEKLHDTLFRGNNKNK------------------------------GSSDEALVEELANFRTLVYCSLCSKNWKNMAIKTCGHVFCENCCKERLAARMRKCPTCNKAFSSNDLLTVHL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :* : : .*: *::: * . :::* **.: * .:. . * : * . :..: : : . :.. * . . ..:. *. . : : *: ** :* : : *:* . : : : :: * .. : :.:*: * :: . .: * :: :.*:: * : . : : * :* :* *:.. **: : : :. ::. ..*.:*. :.:** :. ::: : : :* :: : :.*. :* :: * *: .: :*: .: * : : *.:* :: . . : .: . .: : :. ::: : : *: :.:* : :. : ..* .: ::: *:::*.. ::.*.: :.: .:: :.::: *: . : . . ::::* *:.. .:::.. :* *: **::.* :*:.::* *::: :: . .: : : .*::.. *: :: :::* : : * :: .:* : .: .:: .: : : . : ** : **: ::: : *. *. . *: .:..* **** :* : * :* ****.** **.::* ::: ", "identical_positions": 89, "similar_positions": 270, "identity": "8.48%" }, { "cls_id": "homologset.agr.MGI:2142062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AF29-1", "uniprot_id": "A0A8I6AF29_RAT", "id": "A0A8I6AF29-1", "name": "Protein SPT2 homolog", "aln": "MDFREILLIASKGQGVN----HVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLRRKEEELRRKALEEKKRKEELVKKRIELKHDKKARAMAKRTKDNFHGYDGTPIEEKTKKRQVVESPLN-QGTDQEY---DMEEE-DFIEYNQADLDQDYEEEQEPP---------KVESKPK---APLKSAPSPMNFTDLLRLAEKKQFEPVEIKVVKKAEDRPLTAEELREREFLERKHRKKKPEPDAKLPPAMSKRAPSHKDIRGTQPSKGAGDRQPPSKGLPPPHAEKKFRPSTANEKQVALPSSKSLPGERTKVGSGSSSQPSLREGHSRPVFNGAGKSHPSTCAPSVPKTAASGTQKSASEHKAKKSLSSHPSHSKPGPTVLSHNKAKSPGVRQPGSNSGSAPGQPGPGTARPALSSGPVPRRQNGSSSSGPEQSVSGIRKPASNSHPSGRTLNGTSGPGRPASSSNGPGRPISGSAGSGRPVGSSGGPGQPINSPHDLRRPMNNLGLPGRSVSGPGRPISGSIPAGRTAS-SGPGRPVSSLGPGRTVSNSGVPTKPKCTVVSETISSKNIISRSSNGQMNGMKPLPSGYRSAQGP---QRLPFPTGYKRP---REYD---DDDDEYDSEMDDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEEMKRRKAKKLKRH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68FG3-1", "uniprot_id": "SPT2_MOUSE", "id": "Q68FG3-1", "name": "Protein SPT2 homolog", "aln": "MDFREILLIASKGQGVN----HVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLRRKEEELRQKALEEKKRKEELVKKRIELKHDKKARAMAKRTKDNFHGYDGIPVEEKTKKKQLVESHLN-QGTDQEY---DVEEE-DFIDYNQAELDQDYEEEQEPP---------KAESKPK---APLKSAPSPMNFTDLLRLAEKKQFEPVEIKVVKKAEDRPLTAEELREREFLERKHRKKKPEPDAKLPPPVLKKAPSHKDIMGTKPSRGAGDRQLASKGLPFPQAEKKFRPSTASEKQAALSSPKSLPGERTKVGSGSSTQPSLREGHNRPVFNGAGKPRPSTCSPSVPKTPASGTQKSASEHKAKKPLPSHPSHSKPGPTVLSHNKSKSPGVRQPGSNSGSAPGQPNPGTARPTLSSGPVPRRQNGSSSSGPEQSAGGIRKLASNSHLSGRTLNGTNGPGRPASSSSGPGRPISGSAGSGRPVGSSGGPGQPVNNPHDLRRPMNSLSSPGRAVSGPGRSISGSIPAGRTVN-SGPGRPVSSLGPGRAVSNPGLPTKPRCTVVSETISSKNIISRSSNGQINGMKPLLSGYRSAQGP---QRLPFPTGYKRP---REYEE--DDDDEYDSEMDDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEELKRRKAKKLKRH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68D10-1", "uniprot_id": "SPT2_HUMAN", "id": "Q68D10-1", "name": "Protein SPT2 homolog", "aln": "MDFREILMIASKGQGVN----NVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLKRKEEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYNGIPIEEKSKKRQATESHTS-QGTDREY---EMEEENEFLEYNHAESEQEYEEEQEPP---------KVESKPK---VPLKSAPPPMNFTDLLRLAEKKQFEPVEIKVVKKSEERPMTAEELREREFLERKHRRKKLETDGKLPPTVSKKAPSQKESVGTKLSKGSGDRHPSSKGMPLPHAEKKSRPSMANEKHLALSSSKSMPGERIKAGSGNSSQPSLREGHDKPVFNGAGKPHSSTSSPSVPKTSASRTQKSAVEHKAKKSLS-HPSHSRPGPMVTPHNKAKSPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVPRRQNGSSSSGPERSISGSKKPTNDSNPSRRTVSGTCGPGQPASSSGGPGRPISGSVSSARPLGSSRGPGRPVSSPHELRRPVSGLGPPGRSVSGPGRSISGSIPAGRTVSNSVPGRPVSSLGPGQTVSSSGPTIKPKCTVVSETISSKNIISRSSNGQMNGMKPPLSGYRAAQGP---QRLPFPTGYKRQ---REYEEEDDDDDEYDSEMEDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEEMQRRRAKKLKRR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGN6-1", "uniprot_id": "SPT2_DANRE", "id": "Q6DGN6-1", "name": "Protein SPT2 homolog", "aln": "MDFDSVLSIASQNQGLS----SLPKRYSLKTGPPKKDLKVGGVNSAAVQAFLKKKAVEQKNKEQQDKKAKEDLLAKRVELKSDRKARAMASRTKDNFRGYNGIPVIDQPKKRQSKGSSTEEQQSSTKYEGGDYDDE-DNFDYEGTDSESEPSRPVKPQAISRPEYSNRVENKPKKLSAPARPASSSMNFADLLKLAEKKQFEPVELKVVKKTEERLRTAEEIRE---LEMERRVKKLDKGKDVRSDKNSGQKDSRSQTSSNPQKKHVDRDGKNGRFPRPSEEKHQSSSTSKKPKLQASSERTPTSAKLHGDRSNSG------------------SSGALNSKSAMKNGASFQAKQAPPRPSQGQRPATPSDLTPRKGNVSLTQAKS-------SISGSCP----PGAARP--GQGPHKNSAHGRPSN--FSTSGPSQKPANPGKLSR---PGSNAPPRPGGS--GVVRPFTGDP-SKQPR-----PGGNLQSQQFPGSSRASLNGPKRMERG----VSGSQ-INRMSS-----------GPGRSQ----------CTVVSETISTKNITPRPG---MVQRPPGPQGPRTVIGPSGHRILVKPSGPALPPITSSYKRKFEDEEEYDSEMDDFIDDEGEDQDEISKHIREIFGYDKNKYKDESDYALKFMESSWKEQQKEEARSLRMAVLEDEEEERRELEEMQRKNAKKRK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMP6-1", "uniprot_id": "SPT2_DROME", "id": "Q8IMP6-1", "name": "Protein SPT2 homolog", "aln": "MDFGDLLRYAKKNSDAVTKEVGQGKYYSTKYSPPKKQSKESKQLSSNIQKFLQKKEAEEAEKKRLERQKLNDLLAKRDEKSKN-KIRKMLKVTKS----ANKSVLEDAKDYEGAIDGHEAGEGQGDDYGYVSTEANAFYDKYIEKVRDVQEDKGFTPS-------------RPQ-------SLKDLSGTKERVKAAITREREEAKGNTRQKSSTSTLPSSATKS-----KESSVARSYSTSKTLYDPNAEKLEEERKKRQEEEQRRAKIKRPAQPPPMDFQALLRLAEKKQHEPVVFEVEKKKEPERLLSAR-----------------------EKRELEERQRQQEQRAQRLKMRESEGKETPKSIPNRMEPNGRIPKLNQAKP----------ANAP----SDSFKKPTAPQPTKSSASSTSLSSSNSHSSASRSSVSSSRPATKSAQLTARPGATASAVGKPSSSSSRDVPSKNPYAATSLKGTVREFPPRDQSSISTLDRRK---------IPAAAKTRQTPS----------------------------SDVQRSQGGRQFPPADVKRRKPNEPPVTKR-------------------------RIYDD--DDEDEYDSELDDFIDD-GDCEEDISSHIRDIFGYDKRRYQG-IDDDDRGMESSFAQVQREEFISKKLGMQEDLEDMRMEAAHKKQKKLVAKISSRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .:* *.:... * ** .****: * *: :* **::* * .* ::: ::*: ** * . : * * * . **. : : : . . . : . .* . : : .* : : .. * :*: . . : :: * .:: * .: :. :*:. .:. :. : : . . . : .: . . * .. .. :. : : . .: *. * .::*. ...* .. : . * . . . . :. .. .. : : * ...: . : . * .* * . . *. :..: : . : *..: . ::: . * . *. :*::*****::***:* *: :::**.***:*****:.:*:. * : ****: : *:** * ::.: ** *: * * . :::. ", "identical_positions": 86, "similar_positions": 167, "identity": "12.04%" }, { "cls_id": "homologset.agr.MGI:2142075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A5J1-1", "uniprot_id": "A0A8I6A5J1_RAT", "id": "A0A8I6A5J1-1", "name": "Asparaginyl-tRNA synthetase", "aln": "MLGARRLLGALRLCSSVSCPRPRATAKLRVRDALGVQDASGECVTVQGWIRSVRSQKEVLFLHVNDGSSLESLQVVA-----DSSFDSRELAFGSSVQVQGQLVKS-QSKRQNVELKAEK----IEVVGTCEAKAFPIKYKERHPLEYLRQYPHLRCRTNALGSILRVRSEATAAIHSYFKDNGFMHIHTPVLTSNDCEGAGELFQVEPSSKIKVPEENFFDVPAFLTVSGQLHLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMVEAEVSFVESLQDLMQVMEGLFKATTEMVLSHCPEDVELCHQFIASGQ----------------KDRLEHMLKNNFLIISYAEAIEILKQAS---QNFTFTPKWGVDLQTEHEKYLVRHCGNIPVFVINYPSELKPFYMRENEDDPQNTVAAVDLLVPGVGELFGGSLREERYHVLEQRLARSGLTKA--YQWYLDLRKFGSVPHGGFGMGFERYLQCILGVDNIKDVIPFPRFTHSCLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGV0-1", "uniprot_id": "SYNM_MOUSE", "id": "Q8BGV0-1", "name": "Asparaginyl-tRNA synthetase", "aln": "MLGARRLLGALRLCSSVSCPRPRASAKMRVRDALRVQDARGECVTVQGWIRSVRSQKEVLFLHVNDGSSLESLQIVA-----DSSFDSRELTFGSSVQVQGQLVKS-QSKRQNVELKAEK----IEVIGDCEAKAFPIKYKERHPLEYLRQYPHLRCRTNALGSILRVRSEATAAIHSYFKDNGFVHIHTPVLTSNDCEGAGELFQVEPSSKIKGPKESFFDVPAFLTVSGQLHLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMVEAEISFVESLQDLMQVMEELFKATTEMVLSHCPEDVELCHQFIAAGQ----------------KGRLEHMLKNNFLIISYTEAIEILKQAS---QNFAFTPKWGVDLQTEHEKYLVRHCGNIPVFVINYPSELKPFYMRENEDGPQNTVAAVDLLVPGVGELFGGSLREERYHVLEQRLARSGLTKA--YQWYLDLRKFGSVPHGGFGMGFERYLQCILGVDNIKDVIPFPRFTHSCLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96I59-1", "uniprot_id": "SYNM_HUMAN", "id": "Q96I59-1", "name": "Asparaginyl-tRNA synthetase", "aln": "MLGVRCLLRSVRFCSSAPFPKHKPSAKLSVRDALGAQNASGERIKIQGWIRSVRSQKEVLFLHVNDGSSLESLQVVA-----DSGLDSRELNFGSSVEVQGQLIKS-PSKRQNVELKAEK----IKVIGNCDAKDFPIKYKERHPLEYLRQYPHFRCRTNVLGSILRIRSEATAAIHSFFKDSGFVHIHTPIITSNDSEGAGELFQLEPSGKLKVPEENFFNVPAFLTVSGQLHLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMIEAEISFVDSLQDLMQVIEELFKATTMMVLSKCPEDVELCHKFIAPGQ----------------KDRLEHMLKNNFLIISYTEAVEILKQAS---QNFTFTPEWGADLRTEHEKYLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLVPGVGELFGGGLREERYHFLEERLARSGLTEV--YQWYLDLRRFGSVPHGGFGMGFERYLQCILGVDNIKDVIPFPRFPHSCLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25345-1", "uniprot_id": "SYNM_YEAST", "id": "P25345-1", "name": "Asparagine--tRNA ligase, mitochondrial", "aln": "MFHAFTFLKGGRFYSSLTVKSLYE----------QVHHTSHDPISINGWIKSIRLLKRIAFLDLQDGTSVNPLRIVIPLTNTDEVQFLKILKTGQTLSISNATWQSTPNRKQPFELQIKNPVKSIKLVGPVSEN-YPLQ-KKYQTLRYLRSLPTLKYRTAYLSAILRLRSFVEFQFMLYFQKNHFTKVSPPILTSNDCEGAGELFQVSTNTSPTAS--SYFGKPTYLTVSTQLHLEILALSLSRCWTLSPCFRAEKSDTPRHLSEFWMLEVEMCFVNSVNELTSFVETTIKHIIKACIDNQQE--LLPKQFISSQENNASSELSINQETQQIKTRWEDLINEKWHNITYTNAIEILKKRHNEVSHFKYEPKWGQPLQTEHEKFLAGEYFKSPVFVTDYPRLCKPFYMKQN-STPDDTVGCFDLLVPGMGEIIGGSLREDDYDKLCREMKARGMNRSGELDWYVSLRKEGSAPHGGFGLGFERFISYLYGNHNIKDAIPFYRTSAESIDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . :* . *: ** . .:.: : :.::***:*:* *.: **.::**:*::.*::* *. : * *.::.:.. :* .::* .**: :: *:::* . : :*:: *: :.*.***. * :: ** *.:***:** . : :*:.. * :: .*::****.********:... . . . .:*. *::**** *****::: :::: :*:.* ****:*:: ***:**:*:*.*:.**:*:::* ..:* :* :.: * * ::**:. : * * *.:::::: *:*::*:****: .:* : *:** *:*****:*. . : **** :** *****::* . *:.**...******:**::**.***: *. * ..: *:.. :**:.**: **.******:****::. : * .****.*** * . ..: ", "identical_positions": 170, "similar_positions": 180, "identity": "33.4%" }, { "cls_id": "homologset.agr.MGI:2142077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWT9-1", "uniprot_id": "A0A1B0GWT9_RAT", "id": "A0A1B0GWT9-1", "name": "", "aln": "--------------------------------------------------------------MDPAVLVDAIVEEVN------------CPICMTLLREPVSITCGHTFCHSCLSGLWRLP-GDSQNLSYTCPLCRAPVQPRKLRPNWQLASVVDKVRL--------LGFCMEMGLKTDMCDLHKEQLTMFCKEDDVVTCKACNKSPEHGAHSVVPIKDVAWEYKWKLQQALEHLRKEQEKVWKLEVSEKEQAAIWKTQMETRKQSILWEFEKYQQLLKEKE-LPCQQAEEEAAAVQAGLEQEKGEMGNKLRLRHEKMIQQSQVLWQMIVELEERSQRPVRWMMQGIQEALNRSKSWSLQQLEPISLELKTDCRVLGLREILKTFAVDVRLDPDTAYSRLVISKDRKSVHYGVTQQNLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCVESVDRKEVVYLSPRYGFWVIRLRKGTEYRAGTDEYPLLPLSVPPHRVGIFLDYEAHDISFYNVTDAGSHIFTFPRYPFPGRLLPYFSPCYSIGTNNTTPITICTLDGEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K243-1", "uniprot_id": "TRI68_MOUSE", "id": "Q8K243-1", "name": "E3 ubiquitin-protein ligase TRIM68", "aln": "--------------------------------------------------------------MDPAVLMEAIVEEVN------------CPICMTFLREPVSISCGHTFCHSCLSGLWKLP-GESQNLSYTCPLCRAPVKPRKLRPNWQLASVVDKVRL--------LGFCMEMGLKTDVCDLHKEQLTMFCKEDDMVTCEACKQSPEHEAHSVVPIKDVAWEYKWKLQQALEHLRKEQEEAWKLEVSEKEQAAIWKTQMERRKQSIRWEFEKYRQLLKEKE-LPCQQAEEEAAAAQASLEQEKGETASKLELRREAIIRQSQVLWSMIVELEERSQRPVRWMLQGIQEALNRSESWTLQQLEPISLELKTDCRVLGLRETLKTFAVDVRLDPDTAYSRLVVSKDRKSVHYGVTQQNLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCVENVDRKEVVYLSPRYGFWVIRLRKGTEYRAGTDEYPLLPLTVPPHRVGIFLDYEAHDISFYNVTDGASHIFTFPCYPFPGRLLPYFSPCYSIDTNNTTPLTICTLGGEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AZZ1-1", "uniprot_id": "TRI68_HUMAN", "id": "Q6AZZ1-1", "name": "E3 ubiquitin-protein ligase TRIM68", "aln": "--------------------------------------------------------------MDPTALVEAIVEEVA------------CPICMTFLREPMSIDCGHSFCHSCLSGLWEIP-GESQNWGYTCPLCRAPVQPRNLRPNWQLANVVEKVRL--------LRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFEKYQRLLEKKQ-PPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYSIGTNNTAPLAICSLDGED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GIM4-1", "uniprot_id": "A0AC58GIM4_DANRE", "id": "A0AC58GIM4-1", "name": "", "aln": "MRRHVQTSLTKSDVMRETPANFQQDQNPETPPILSPSQQESQSRRARRTEQSMSSSLPAQNKMDKQKLRPEIPPRVSKSSAQRLSRDLTCSICLDLFKQPVSLPCDHTFCEACITSYWSGPRVKCQAGSGSCPQCRKVFHGKSYRPNRIVANIVESYCQGMEESGVRLGAVSEPAPTAPLCMRHREELKLYCEEDQELVCLVCGISQDHRAHTLVCVQDAQKRYRASLTTSANALQKELNTALECERETEEEVKKLKDHTADLKQRIEAQFSELHQFLYQEEKLLQVKLKTEERRELIRLDEHKALLSVEISRLRRAVN---DIEDKLSEQDPYTLLRSIKGLLQRQPPKFERPTLTPPSLCEGRFAGPLQYRVWKSLKGSIYPVPSAITFNSKTANPWLSLTSSLTCVRYQTFNSSVQDNPQRFNAALSLMGGQGFTKGRHYWEVEVYSSTVWTVGVARESVTRKGVINTMPANGFWTLSLSYGVQYMAGTSPPTLLSLEEPLARIGVYLDYKRGLVSFYN-AESMTHLYTFR-DTFTETLFPYFNLGFLDKVHENEPLKVFMPKI--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * * .* *.**: ::::*:*: *.*:**.:*::. * * ..* . :** ** .: :. *** :*.:*:. * . . :* * *:*.::*:** : * .* * :* **::* ::*. .*: .* : : *:** : . : * .:.. * : ** * :*.: :::* ::: : * *:.. . :: : : :: : : *.:: ::* ::*. . . * .*: : . . : ::..** . * ::.. . *:* :..: ***:** ::*.* ::.********* . : * :**. :.* ** *: * ***.: * * :* ***. .:*.* * *:*:::**: :**** :: :*::** .*. *:***. : .::. *: : ", "identical_positions": 120, "similar_positions": 155, "identity": "21.09%" }, { "cls_id": "homologset.agr.MGI:2142116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q812D1-1", "uniprot_id": "PSIP1_RAT", "id": "Q812D1-1", "name": "PC4 and SFRS1-interacting protein", "aln": "-----------MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYG--KPNKRKGFNEGLWEIDNNPKVKFSSQQ---------------------------------------VSTKQSNASSDVEAEEKETSVSKEDTDQEEKASNEDVTKAADITTPKAA-----------------------------------------------------------------------------------------------------------------------------------RRGRKRKAEKQVDTEEAGVVTAATAS-NVKASPKRGRPAATEVKIPKPRGRPKVVKQPCPSESDMVIDEDKSKKKGPEEKPPKKQLKKEEEGQKEEEKPRKEP-----------------------------DKKEGKKEVESKRKNLAKPGVTSTSDSEED-DDQEGEKKRKGGRHFQAAHRRNMLKGQHEKEAADRKRKQEEQMETEQQTKDEGKKPEVKKVEKKRETSMDS-------------------------------------------RLQRIHAEIKNSLKIDN--LDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLN-----------KSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGTKSLNGGSDAQESNHPQHNGDSAEESKDSREAGSKTKTPGEEREAEVSLKESTLDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JF8-1", "uniprot_id": "PSIP1_MOUSE", "id": "Q99JF8-1", "name": "PC4 and SFRS1-interacting protein", "aln": "-----------MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYG--KPNKRKGFNEGLWEIDNNPKVKFSSQQ---------------------------------------ASTKQSNASSDVEVEEKETNVSKEDTDQEEKASNEDVTKAVDITTPKAA-----------------------------------------------------------------------------------------------------------------------------------RRGRKRKAEKQVDTEEAGMVTAATAS-NVKASPKRGRPAATEVKIPKPRGRPKVVKQPCPSDGDMVIDEDKSKKKGPEEKQPKKQLKKEEEGQKEEEKPRKEP-----------------------------DKKEGKKEVESKRKNLAKPGVTSTSDSEDE-DDQEGEKKRKGGRNFQAAHRRNMLKGQHEKEAGDRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDS-------------------------------------------RLQRIHAEIKNSLKIDN--LDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLN-----------KSLAEQRQHEEANKTKDQGKKGPNKKLEKEPTGTKSLNGGSDAQESNHPQHNGDSNEDGKDSREASSKTKPPGEEREAEISLKESTLDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75475-1", "uniprot_id": "PSIP1_HUMAN", "id": "O75475-1", "name": "PC4 and SFRS1-interacting protein", "aln": "-----------MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYG--KPNKRKGFNEGLWEIDNNPKVKFSSQQ---------------------------------------AATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAA-----------------------------------------------------------------------------------------------------------------------------------RRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEP-----------------------------DKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDS-------------------------------------------RLQRIHAEIKNSLKIDN--LDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLN-----------KSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNGGSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AH76-1", "uniprot_id": "A0A8M3AH76_DANRE", "id": "A0A8M3AH76-1", "name": "", "aln": "-----------MAQDFKAGDLIFAKMKGYPHWPARIDEIPDGAVKPSNIKFPIFFFGTHETAFLGPKDIFPYLTNKDKYG--KPNKRKGFNEGLWEIENNPKVELNGHK---------------------------------------VKKVG--------------EVSIKDLSSNEEGDDEKRTKSAQIAHSEG-----------------------------------------------------------------------------------------------------------------------------------------LEDEVDIEKEDGG---------DMDVSDQR-----------------------------LVKDEDLS------QKDSTNVTAKAKRGRKRKSDAEQDS-----------------------------DTENSSPTAGGSGLDFLSTGTS-----------------------IMLLKRR----GRKSKTEKSIILQQQASKELPRSGKD-GKR-DERKGDKRKEVSAES-------------------------------------------TLQKLHGEIKTSLKIGN--LDVRKCVHALDELSSLHVTTQHLQRHSELIATLKKICRFKSSQDVMDKAIMLYNKFKSMFLMGEGESVLSQVLN-----------KSLTEQKLFEEAKRG-----VLKNTEQTKEQKDTKILN------EDFNSEEDAETEKDKLGGNILSMVKNNLTNPAEESV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PX56-1", "uniprot_id": "A0A8M9PX56_DANRE", "id": "A0A8M9PX56-1", "name": "", "aln": "MQKGVKMKSDQTTDDFTPGDVVFAKMKGYPFWPARIAEG-----KAPKNKIPIFFYGTHSTTFLFPKDIVHYWPNKQKYA--QANKRGGFEEGMWEIENDPGVGLRGQKKAALVKRLSESRLKWKNKKKKKAENQTEVKKPPKSAKDPVSNSDSKAATPHKRETKSESVTLKDDKNTETRPTRSRDSSAKTSTDKRRTDKVVPARKMTSVKTITTGWRRLPSSVILARRMDAAKTLSAHRKHVLNRKIISTAKKRIDAVNHRKPSRITRSTADPIEATDDVTAKPLALKRKRKQNDSEVKGDAPISIPATDISASSTPTGSKRRRLTEPEKKSKDDEKELKENEAQSKEKNEVEQKIEKQNEVEKSNADKNKMMEKKNQAEKIVAENETENKGAKKKESEKSDAEKEKSEKKETKKIETERKEARNSEAESKEPCKNDSEKKEAERIETRKSESEVLVAKNKESEKRETRKSESEMKEARKNESKKQEARKSESEKRETRKSESEMKEARKNESEMKEARKSESEKRETRKSESEMIEARKNESEMKEARKSESERRETKNSEAEIKEARKNESEIEAIRSNSEKRETRKSDSEMEAKNNESEKREAGKSESEMKEARKNESEKKEARKRETRKSESDMKEAKRKETRKSESEIKVAKDNDSEKRETTKNESEIEAKNKESEKREAGKSESEIKEARKNESEKEEARKRETRKSESDMKEARKNESEIKVAKDNDSEKRETRQNEFEIETKNNESEKRETRKSESEMKEARKTDSEIIEAKKNESEKESKRDESEKRETRKNESEMKEARKNESEKRAIRNESEKRETKSQSEIKESEKREARNIESEKKEAKKIDSEMKQARKNESEKKEARKSESEKKEAERVETRKTESEKKEVRKSESEKKEAERKLERKSESERKEAKKSESENKEARGNESEKKGARRSESEKKEARQSESEKKEARRSESEKRENRRSESEKKEARRNESEKRETRSESEKRETRRNESEKREPRWRESEKKETRRRESEKKETRRSESEKKEPRSESKKKEARRSESEKKEARRSEFEKKEARRSEFEKKEARMSESDKKEAKRNESEKKEARRSEFEKKEARRSEFEKKEARMSESEKARRSEFEKKEARRNESEKKDARRNESEKKEARRNESEKKEARSESEKKEARRNESEKNEGRRNESEKKEERRIESEKKEARKNKSEKEARRSDSELKEARRKESELKEARRNESVKSDAEKDAVEKNKAEKNKLPEKRKEINVEERRETMTKPKQTKSCAPVSSDETQEEKKPRDEERCKILAEKRQSVLKSLQGLVTSTRGKTPSGSEQTTETKEPRKERNHRLKQPAEDEKKDTEKRKEQEKRNTEQQISSSKEEERRAHSLSVTDSLLYRLHGDIRISMTLENPDVSKCLSALDELSNVPVSSRNIQNHSELIDTLRKMRWFRGSEAIMFKASMLYHRFKNIYLIGDADETLSQEYINSLQQEREREIEERHRDAVRTEADVRKTPDFTSCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAA9-1", "uniprot_id": "Q9VAA9_DROME", "id": "Q9VAA9-1", "name": "", "aln": "------MGKEKAAASYSIGDLVFAKVKGYPPWPAKITKS------NNNKKYNVYFYGTGETANIKLEDLFPYASNKERFATEKIMKRAKFIEAIDQIESALRGED-------------------------------------------SAPIDLLDGAEPVAPPTTGDGVKTEEPKPEPGPEPATAAPVAAAAEKPK----------------------------------------------------------------------------------------------------------------------------------------KSGTRKTKAPPRHVDGDSEAGAELAPPPAKRR----------------------------VPTEGLATAAAIPAAPAAATPTSSKKSVKKSKPTAAVTP---------------------------IQKRSRPVNNIRNEMLMVYMPTAKCLGIVINYKKPESFESAAAEEAWMENARKEALELKLKLESGQINPESMPDRIVVEPTRSEIPKQEALRFIEELIEHEDALFMER--------------------------------------DFIQLSQQLRECLGLRR--ANVGKCLEILEQFKEVEFTKLMLLRNPECVDIMRRLRRYVGNLELWKMDLSDEVEFKER------------------------------AQTIRKVSSGIYDGFKSLFNPEPESEDNFWIDFCEKVKIYKTYTKNINENLRVGMNERGYNSLVLAKEAAASAGSAPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:. **::***:**** ***:: : . * ::*:** .*: : :*:. * **:::. : ** * *.: :*:. . : * .. : : . . . .: : . : *. . . :... . : :. . . . . :. : : .. :: : ::: . :. : .: . . : . : : . . : .. : : : : . .. . : . : . . . ", "identical_positions": 28, "similar_positions": 102, "identity": "1.84%" }, { "cls_id": "homologset.agr.MGI:2142121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCA8-1", "uniprot_id": "M0RCA8_RAT", "id": "M0RCA8-1", "name": "Purple acid phosphatase", "aln": "MPSGGLRGSPDFGKQEGDERKMLRARPRWMGTPELRPPVGLRHLLHHSPQRRFSHSAFLPHGHPDRRTEGPAWHRSILHPLWDPPTEFDPTPAFLDTSHHPPTMSPFLGGWLF-CLLLLFSLG------VQGTPEYPRATPEQVHLSYPGE--PGTMTVTWTTWAP-------ARSEVQFGTQLSG--PLPLRAHGTSSAFVDGGVLRRKLYIHRVTLRKLLPGAHYVYRCGSSQGWSRRFRFTALKNG-VHWSPRLAVFGDMGADNPKALPRLRRDTQQGMFDAVLHVGDFAYNMDQDNARVGDRFMRLIEPVAASLPYMTCPGNHEQRYNFSNYKARFSMPGDNEGLWYSWDLGPAHIISFSTEVYFF-LHYGRHLVEKQFRWLERDLQKANK--NRVARPWIITMGHRPMYCSNADLDDCTRHESRVRKG---LQGKLFGLEDLFHKYGVDLEFWAHEHSYERLWPIYNYQVFNGSL-ERPYTNPRGPVHIITGSAGCEELLTPFVRKARPWSAVRVKEYGYTRMHILNGTHLHIQQVSDDQDGKIVDDVWVVRPLLGRMMYH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BX37-1", "uniprot_id": "ACP7_MOUSE", "id": "Q8BX37-1", "name": "Acid phosphatase type 7", "aln": "-------------------------------------------------------------------------------------------------------MSPFLGGWLFFCMLLPFSPG------VQGAQEYPHVTPEQIHLSYLGE--PGTMTVTWTTWAP-------ARSEVQFGSQLSG--PLPFRAHGTARAFVDGGVLRRKLYIHRVTLRKLQPGAQYVYRCGSSQGWSRRFRFTALKNG-VHWSPRLAVFGDMGADNPKALPRLRRDTQQGMFDAVLHVGDFAYNMDQDNARVGDRFMRLIEPVAASLPYMTCPGNHEQRYNFSNYKARFSMPGDNEGLWYSWDLGPAHIISFSTEVYFF-LHYGRHLIEKQFRWLENDLQKANK--NRVARPWIITMGHRPMYCSNADLDDCTRHESRVRKG---LHGKLFGLEDLFHKYGVDLEFWAHEHSYERLWPIYNYQVFNGSL-ESPYTNPRGPVHIITGSAGCEELLTPFVRKPRPWSAVRVKEYGYTRMHILNGTHMHIQQVSDDQDGKIVDDVWVVRPLLGRMMYH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNF0-1", "uniprot_id": "ACP7_HUMAN", "id": "Q6ZNF0-1", "name": "Acid phosphatase type 7", "aln": "-------------------------------------------------------------------------------------------------------MHPLPGYWSCYCLLLLFSLG------VQGSLGAPSAAPEQVHLSYPGE--PGSMTVTWTTWVP-------TRSEVQFGLQPSG--PLPLRAQGTFVPFVDGGILRRKLYIHRVTLRKLLPGVQYVYRCGSAQGWSRRFRFRALKNG-AHWSPRLAVFGDLGADNPKAVPRLRRDTQQGMYDAVLHVGDFAYNLDQDNARVGDRFMRLIEPVAASLPYMTCPGNHEERYNFSNYKARFSMPGDNEGLWYSWDLGPAHIISFSTEVYFF-LHYGRHLVQRQFRWLESDLQKANK--NRAARPWIITMGHRPMYCSNADLDDCTRHESKVRKG---LQGKLYGLEDLFYKYGVDLQLWAHEHSYERLWPIYNYQVFNGSR-EMPYTNPRGPVHIITGSAGCEERLTPFAVFPRPWSAVRVKEYGYTRLHILNGTHIHIQQVSDDQDGKIVDDVWVVRPLFGRRMYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5D6U8-1", "uniprot_id": "ACP7_DANRE", "id": "A5D6U8-1", "name": "Acid phosphatase type 7", "aln": "-------------------------------------------------------------------------------------------------------MAAAPPPPPPLLLLLLCVCA------VFADVPIG-TQPEQVHISYPGV--QNSMLVTWSSANK-------TDSVVEYGLWGGK--LFSHSATGNSSIFINEGAEYRVMYIHRVLLTDLRPAASYVYHCGSGAGWSELFFFTALNES-VFFSPGFALFGDLGNENPQSLSRLQKETQIGTYDVILHIGDFAYDLYEDNGRIGDEFMKQIQSIAAYVPYMTCPGNHEWAFNFSQYRARFSMPGDTEGLWYSWNVGPAHIISFSTEVYFYYLEYGLDLLFRQYEWLRADLQEANRPENRAERPWIITMGHRPMYCSNDDDDDCTHFQSYVRLGRNDTKPPAPGLEELFYQYGVDLELWAHEHTYERLWPVYDYKVFNGSS-EEPYVNPKAPVHIITGSAGCREKHDGFIPKPRDWSAFRSTDYGYTRLQLINNTHLYLEQVSDDQYGKVIDQMTLVKEKHGPDAWR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JB52-1", "uniprot_id": "X2JB52_DROME", "id": "X2JB52-1", "name": "Purple acid phosphatase", "aln": "-------------------------------------------------------------------------------------------------------MQRLQFALLASLLLLVLLLPGIRSTPIDQDVDIVHYQPEQVHLSFGAERTDSEIVVTWSTRSLPPDQEVGAVSVVEYGQLVDGQVRLTQQARGKATKFVDGGHKQATQFIHRVTLRDLEPNATYSYHCGSDFGWSAIFQFRTVPSASVDWSPSLAIYGDMGNENAQSLARLQQETQRGMYDAIIHVGDFAYDMNTKNARVGDEFMRQIETVAAYLPYMVVPGNHEEKFNFSNYRARFSMPGGTENMFYSFDLGPVHFVGISTEVYYF-LNYGLKPLVFQFEWLREDLAKANLPENRNKRPWIILYGHRPMYCSNENDNDCTHSETLTRVG--WPFVHMFGLEPLLYEFGVDVAIWAHEHSYERLWPIYDYKVRNGTLKDSPYNDPSAPVHIVTGSAGCKEGREPFKGKIPEWSAFHSQDYGYTRLKAHNRTHIHFEQVSDDKNGAIIDDFWLVKSKHGSYRN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :** : ***:*:*: . . : ***:: : * *::* . :. * *. *:: * :**** * .* * . * *:*** *** * * :: .. . :** :*::**:* :*.:::.**:::** * :*.::*:*****:: .*.*:**.**: *:.:** :***. ***** :***:*:*******..*.::**:::**.*::.:*****:: *.** . : *:.**. ** :** ** ***** ********* : :***: :: .* * *** *::::***: :*****:******:*:*:* **: : ** :* .****:******.* * ***.: :*****:: * **::::*****: * ::*:. :*: * ", "identical_positions": 182, "similar_positions": 122, "identity": "32.16%" }, { "cls_id": "homologset.agr.MGI:2142124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PWS4-1", "uniprot_id": "E9PWS4_MOUSE", "id": "E9PWS4-1", "name": "", "aln": "MLWVLPPPTLKNFQLLCSTDLELCPRNTSS---------TPGFHPVSAEFGSLHQALKMLWQNLHQFGQKLVRRRP-LAANEQSESSLSRCLTTLDLVSLGVGSTLGAGVYVLAGEVAREKAG--PSIIICFLIAALSSVMSGLCYAEFGARVPCSGSAYLYSYVTVGQLLAFITGWNLILNYVIGAASVARAWSAAFDGLIGNHISQAMQTTFPIQVPSFLAKYPDFFALGLVIVLTGILALGARESALVTRVFTGVNLLVLCFVSLSGLINGKLHNWQLTEDDYKLALLESNNTDSLGPMGSGGFMPFGLKGILRGTATCFFAFIGFDCIASTGEEARCPQRSIPLGIVTSLFICFLM-YFGVSGALTLMIPYYQININSPLPQAFIHVGWGPA--RYAVAVGTLCALSSSLIGSIFP--VPRVVYSMAEDG--LLFRKLAYVHPRTHTPVLATVLCGIIAAFMAFLVELSDLVDLSSIGTLLAYTLVTFSVLILRYQPDQVLSSCKREKSESAAVELEPGLEPSSCMEPISPEGMPGIARTLCIPTNTTPTLRSGRIVYGCASLLVFLLMLLCLILTQWSTQLFSGDPVLIAMAASLLLLTVGVITVIWRQPQSTTPLHFKVPALPVLPALSIFVNIYLMMQMTSGTWFRFGIWMVIGFAIYFGY------------------------GIQHSLEE---------------KNDQQPTASSSQTLQE----------------------------------------LQEHTPSVDLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBE1-1", "uniprot_id": "D3ZBE1_RAT", "id": "D3ZBE1-1", "name": "", "aln": "---MLNMQQTSAFHVLQKATRDLSSWDYRSGAQPWEPIQHSRFSSSVSEFGSLHQALKMLWQNLHQFGQKLVRRRP-LAASEQSESSLSRCLTTLDLVSLGVGSTLGAGVYVLAGEVAREKAG--PSIIICFLIAALSSVMSGLCYAEFGARVPCSGSAYLYSYVTVGQLLAFITGWNLILNYVIGAASVARAWSAAFDGLIGNHISQALQTTFPIQVPSFLAKYPDFFALGLVIVLTGILALGARESAMVTRVFTGVNLLVLCFVSLSGFINGKLHNWQLTEDDYKLALSETNSTDSLGPLGSGGFMPFGLTGILRGTATCFFAFIGFDCIASTGEEARCPQRSIPLGIVISLFICFLM-YFGVSSALTLMMPYYQININSPLPQAFIHVGWGPA--RYAVAVGTLCALSSSLIGSIFP--VPRVVYSMAEDG--LLFRKLAQVHPRTHTPVLATVLCGVIAAFMAFLVELSDLVDLSSIGTLLAYSLVAFSVLVLRYQPDQNLSSCKKEKSDSMAVELEPGLELSSCMEPMSPEGTPGIARGLCMPMDTTPTLRSGRIVYGCASLLALLLVFLCLILVQWSTQLFSGNPVLIAVAVSLFLLTVGVVTVIWRQPQSTIPLHFKVPALPVLPVLSIFVNIYLMMQMTTGTWIRFGIWMVIGFAIYFGY------------------------GIQHSLEE---------------KNDQQPTASSSQTP-------------------------------------------QEHTPSAELP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VVM0-1", "uniprot_id": "Q9VVM0_DROME", "id": "Q9VVM0-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "------------------------------------------MEEFAEYYGMPSWSVTNAFR-------VLTRKK--PLEDSN-ESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAG--PAVVVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNI-EGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEG------------YGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLA-YFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVA--EYVVSIGAMFGLCSSMMGAMFP--LPRIVFAMSNDG--LLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYE--------VDDRRESRIVANGRATGLEQDRP------CALWRRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDILTWIRFSIWIAIGLAIFLAY------------------------GIRHSR----------------LRQREQRNNSIAMMRDC--------------------------SNSALLGGQENS-KYSNEVPLILMHSTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNP7-1", "uniprot_id": "Q9VNP7_DROME", "id": "Q9VNP7-1", "name": "", "aln": "--------------------------------------------------------MTNLWK-------ALTRRK--TEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAG--PAVTISFLIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDSLINNNMSKALNESMHIDV-DFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLVAGAMNANVDNWRIPKKDVPEG------------FGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLS-YFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWYTI--KWIVTIGAVFALCTSLLGAMFP--LPRILYAMGKDG--ILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQ--------DEE-----------MTKLVSVKA------PNVFRQFFNGNSFREPNSMTSSITKVGIVVFAIFCLVWCSLQKVFDLDSTGG----IVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDLNTWIRFLIWIVIGYVIYFCY------------------------GMRNSTQI--------------SRSRSHAEVAASALQNQ--------------------------GQHVNPGFEPDY-KVENGGRPYEFSEKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q2PDY3-1", "uniprot_id": "Q2PDY3_DROME", "id": "Q2PDY3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "-----------------------------------------------------MVRQISPWK-------VLTRRKNLQADGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAG--PSVMISFAIAALASLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLYLDSLLNDTLKYTFAEVAPMNV-SFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGFVIIAGALKADYSNWTVDPSTVSANST----------IGSGGFFPFGFEGTLRGAATCFFGFVGFDCIATTGEEVRNPRKNIPKSILLSLLIIFLC-YFGVSTVLTLMLPYYIQDVNAPLPYAFEYVGWPVA--MWIVTVGGLVGLLASLFGALFP--LPRVMYSMAQDG--LLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRYMD----YCEVDENPGQREVRASETTSLTSSSERFTF--GSVCTQLFNVHRVQEPNAISSRIVGVLSTLFCLISLGIGVLIMQAHLLIASKEVWALTLLIVLVVLMLLVICLICLQPREARRRLFRVPFVPIVPAISIFINIYLMLQLDTWTWIRFGVWMIVGIPVFLACWYLYDCKNPAKRNPERWDFYKALKGLQESREQEYHCISKESVLTLETQLKKSPSSSLNRIQNLSDVGDELVEIKNANGKVFYVEDNKSENSTATLGSNPESPSREDEQSVIAMLDDVLNAQDTQQGQQDLDLQQQMIFERHFSLDSEMYPSVIETVIVATVHSSSDDDEVQSGITLKLSRYDECKLVAHQMLEEMFNSEAFYEQLEKVKAKEVPLVKGDKLEGEAESVNDDEASKPVFLFQRLGSQTSIISQASTIEDPLHSTKFKDRLSHIIMNANAHQVKVVAKRSEDVDGEVELEPVPDEEPKTRPLLKQSKSETDVRRLMLKAISELKIDRNETGNADEVPAEVSTTTGNPSKDPVPGAGPIAAPVAAAGGSNIPRPPKFDPVLYKTINSISLRKQRPSLNRQHIVDAKNPALLRPESQTETRPDPGEQPEPEPLPFKAKLEAILQRGPSHRTQQHPDLVRRQRPQSTYIEMEEVES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32837-1", "uniprot_id": "UGA4_YEAST", "id": "P32837-1", "name": "GABA-specific permease", "aln": "--------------------MSMSSKNENKISVEQRISTDIGQAYQLQGLGSNLRSIRSKTGAGEVNYIDAAKSVNDNQLLAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLGGGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWTYYYAPEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGNFEVTSGKLYG-----IFAGAVVVMCICTCVASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRMGGFNDGDFIFG-----------KYENLSDWNNGWQFCLAGFMPAVWTIGSFDSCVHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINPDIDSVLDSKYGFALAQIIYDSLGKKWAIAFMSLIAFCQFLMGASITTAVSRQVWAFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLAWSTPTVFRLT---------------------------------------SGRDLFRPGPFYLGKIWSPIVAWTGVAFQLFIIILVMFPSQQHGITKSTMNYACVIGPGIWILAGIYYKVYKKKYYHGPATNLSDDDYTEAVGADVIDTIMSKQEP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19807-1", "uniprot_id": "HNM1_YEAST", "id": "P19807-1", "name": "Choline transporter", "aln": "----------------------------------MSIRNDNASGGYMQPDQSSNASMHKRDLRVEEEIKPLDDMDSKGAVAADGEVHLRKSFSLWSILGVGFGLTN-SWFGISTSMVAGISSGGPMMIVYGIIIVALISICIGTSLGELSSAYPHAGGQFWWSLKLAPPKYKRFAAYMCGSFAYAGSVFTSASTTLSVATEVVGMYALTHPEFIPKRW-------HIFVCFELLHLFLMFFNCYGKSLPIISSSSLYISLLSFFTITITVLACS---HGKFNDAKFVFAT-----------FNNETGWKNGGIAFIVGLINPAWSFSCLDCATHMAFEVEKPERVIPIAIMGTVAIGFVTSFCYVIAMFFSIQDLDAVLSSTTGAPILDIYNQALGNKSGAIFLGCLILFTSFGCVIACHTWQARLCWSFARDNGLPLSRLWSQVNPHTGVPLNAHLMSCAWITLIGLLYLASSTAFQSLITGCIAFLLLSYIIPVICLLAK--------------------------------------KRNIAHGPFWLGKFGFFSNIVLLGWTVFSVVFFSFPPVLP----VTKDNMNYVCVVIVGYTAYSILYWKYKGKKEFHALEESENEQAEYSNNFDTIEDSREFSVAASDVELENEHVPWGKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .*.. : . :. :. .* : :.*: * .* .: * :*. : :: .: . . . . . :: . .: . : :: . * : * : : :*. . . *. ..: :* .:: :: : :: : : : : .: : : . : : .* :::..*. * : : .*. . : :. : .. . : :* :: : . . *. : . . . . : : . ", "identical_positions": 18, "similar_positions": 107, "identity": "1.57%" }, { "cls_id": "homologset.agr.MGI:2142149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZNW7-1", "uniprot_id": "A0A8I5ZNW7_RAT", "id": "A0A8I5ZNW7-1", "name": "Anoctamin", "aln": "MQWGAGTGRGEGAAAGDPVTPGAESWGDPRTKAPGAEQRGAGGWAQPSSRLCRSLCWTQGVRSEHIMQDTQDSDISLEGLTREGAPADRECQRGPETIVHEAQDAGTPNSDATGAVDGEREATMRVPEKYSTLPAEDRSVHIVNICA----IEDLGYLPSEGTLLNSLSVDP-DAECKYGLYFRDGKRKVDYILVYHHKRASGSRTLARRGLQNDMVLGTRSVRQDQPLPGKGSPVDVGSPEAPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWHVLCREAEFLKLKMPTKKVYHISETRGL-LKTINSVLQKITDPIQPKVAEHR---------------------------PQTTKRLSYPFSREKQHLFDLTDRDSFFDSKTRSTIVYEILKR---TTCTKAKYSMGITSLLANGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQ-RHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLRKESRNKEKRRNVPEEPTNKWKQRVRTAMAGVKLTDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYIKRK--QRYEVDFNLEPFAG--LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQGKQQLLDTWMEKEKPRD-VPCNNHSPTAHPEAGDSSPVPSYEYHGGAL---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHY3-1", "uniprot_id": "ANO1_MOUSE", "id": "Q8BHY3-1", "name": "Anoctamin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------MRVPEKYSTLPAEDRSVHIVNICA----IEDLGYLPSEGTLLNSLSVDP-DAECKYGLYFRDGKRKVDYILVYHHKRASGSRTLARRGLQNDMVLGTRSVRQDQPLPGKGSPVDAGSPEVPMDYHEDDKRFRREEYEGNLLEAGLELENDEDTKIHGVGFVKIHAPWHVLCREAEFLKLKMPTKKVYHISETRGL-LKTINSVLQKITDPIQPKVAEHR---------------------------PQTTKRLSYPFSREKQHLFDLTDRDSFFDSKTRSTIVYEILKR---TTCTKAKYSMGITSLLANGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQ-RYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLRKESRNKE--------------------------TDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYVKRK--QRYEVDFNLEPFAG--LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQGKQQLLDTWMEKEKPRD-VPCNNHSPTTHPEAGDGSPVPSYEYHGDAL---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XXA6-1", "uniprot_id": "ANO1_HUMAN", "id": "Q5XXA6-1", "name": "Anoctamin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------MRVNEKYSTLPAEDRSVHIINICA----IEDIGYLPSEGTLLNSLSVDP-DAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGL-LKKINSVLQKITDPIQPKVAEHR---------------------------PQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKR---TTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQ-RHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRK--QRYEVDYNLEPFAG--LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDS-LGSPAPSHAYHGGVL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TY29-1", "uniprot_id": "A0AB32TY29_DANRE", "id": "A0AB32TY29-1", "name": "Anoctamin", "aln": "----------------------------------------MDGFPAVTSLSSSSLCMSVDLRRREELTTMTRLESGEEQLQKAG-----------EKLLGFNSTEEQPSGQES----------MWRNEKYESVPLDVKGIDEDNSKG----TRDS--LYPHTTLLKSQQADEKPKDPKLWPYFKDGHRRIDYVLTYHIQKPQNTGKQSSKSCLGGCLCCKKRGQTNPPVPDP----ELASQEQRLDYHDDDQRLRREEFEENLREMGLEMEKEEGNKIPGVGFLKIHAPWEVLCREAEFMKLKMPTIKKYEVSHGNSI-VEKASRFMQKFTAPLQPKVGDRQ---------------------------IEHEKHLSYPFSREKQHLFDLSDRNSFFDSKTRSSIVYEILKR---TKCTRAKYIMGIISLLGNGIYTSAYPLHDGDIDDVHAEINDRKILYEEWASYSIFYKYQPIGLIRKYFGEKVGLYFAWLGVYTQMLIPAAIVGVIVFLYGCATVDDNIPSMEICDE-RNNITMCPMCDRACSYWKLVTACGTARASHLFDNAATVFFAIFMALWAAMFMEHWKRRQVRLNYLWDLTGFEDTES----HPRAEYEFHVMKKSLRKEKSPKAG---------------------------NVKLTCTDRMPAYMTIIITMIFLICVTLAIVFGVVLYRVSIMTALHMSSTPTFRSNIRATVKTTGAIINLIIIIIMDEVYGAVARWLTIMEVPKTDKSFEERLIFKTFVLKFANAFTPIVYLAFFRGRLIGRPGKYIYVMGSYRMEECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGVPKIKKLLR---QRKIDPKHQEELNKTL--HRHEKDHFLGPFVG--LNPEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPIAVRAKDIGIWYTLLRGLSKVAVIVNAFVISFTSDFIPRLVYQYMYSPDGTLHGFVNHTLSYFNVTHFQPGTEPLEPMHLGYQVDTCRYKDYRDPPWSDTPYEFSREFWAILAARFAFVILFQNVVMLMSDFVDWLIPDIPKDISLKIHKERNLIIELFMKREQGKK-----------------YRNTMNDPSPQPLRSRPSSQA----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4JCY1-1", "uniprot_id": "A0A0B4JCY1_DROME", "id": "A0A0B4JCY1-1", "name": "Anoctamin", "aln": "--------------------------------MLNLGSAKVGALEEATSPPPFSKDESFQLLERSPHNPAISPTTTVPLEPPFTTPLAPFDMELMKRHNLHERLTGKESFWRGRDTSQRFLDQEQLSASRESLGAADKRARFAESNAPTLQLPESAEPRANGKRPTGNRTNPSNPAAPLLPMTDPDFVKGNVGGVYDDRECSCPREFYQRGEINTSLFFEDCVRS--------IDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESSQKD---QIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISER-SNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDIR-QDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEITETG---TMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD-WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEE----HPRPQYLARLEHIPPTRVDYVTN-------------------------IKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFD-YRQEECSSGGCLTELCIQLAIIMVGKQAFN-TILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSN---ITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVLQT--PVDQDMDAASIQEPNAKFINIEKLLTENLTQIEMDAIIHGENPITGISGADCLDEVHKKLSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q76NS2-1", "uniprot_id": "Q76NS2_DROME", "id": "Q76NS2-1", "name": "Anoctamin", "aln": "-------------------------------------------MYSAVRTNDYDYPESEMDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRN-HLPTGIGVTGDGGQGGGDDEVSRRLLRTSSNISNKDKKLPITYSQWKSRTYRRFDDGKRSVDFVLAYNG---ETQLEEHRRKCEIFEANLQREGLQLEH---NKVQRVHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNT------------------------ALFPEREPRIHLEFSRNYLELYDTEHPN-FLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHD---------KDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDD--NGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVE----HPRPQYLARISRTKKLAGKAYEQDHTG------------------KRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLG-FRQEECNPGGCLMELCMQLVIIMAGKQAVN-AIVEMLIPYLMRTFKELSYRHGWYKSHQDQRLVP-YNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMG-DPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVN--ETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGELRQRNNETVIRNRDEATSFV-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . : . . : . : :: : . :* ** **::* : *:***** .** * **::*:::* . . : : . : :: :**: *:* : *: : .* *: **.* . :** *: :*:*:.**.*** * * :.** : . **:. ::.*** *:.******* ** **: ::.*:: ***. : .. ::*:. . *** ** *.:* : :* :: .:*:** **.*:. *::**. ::* *** . : : *.**** . ***.:* :: . . :: . . ::::*.::. : .:::**:: :: : .: : :. :::* :: ::: :*. :* ** * :*:..::: * :* ::::*.* ::.:.*:**::*:::* *..* :: :* *** .*** ***:** * * *** .: :.*: :* : : . . .: *. * * **:**::*:*::*:* :*****::*****::*:**** *:: :**:. *.:***:*: :: : :::* ..::*:*::::**::** . : :..::*.**: *:. . ***.::* .* . * . :: :*: *:.*:::::*.: :: :: * :**:. : :*::* : * :: * : : . ", "identical_positions": 197, "similar_positions": 274, "identity": "16.64%" }, { "cls_id": "homologset.agr.MGI:2142166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LBS4-1", "uniprot_id": "A0ABK0LBS4_RAT", "id": "A0ABK0LBS4-1", "name": "C2 domain-containing protein 3", "aln": "MKSSNSVSICACAAAGVLVQPRKGLSDISPSTSLPPLVEGQLRCFLKLTINKVVWKIAKPPASVLVRVRWWGETSDGTLFCPRDALQTEPKAVRTTTRYAIRCGPKQFTSYLTDMAVLVLEVITKFDHLPVGRVQISGLAQLSPTHQINGFFTIVSPASKKLGELQVSLALEPLSETYDSYKPLPATEVTENVLLSERELRENAESSNNQSRIPSGSYRVPAIKTDGKELAGNSSRSTTPRGKDHLYFAENSDAVKSSSCGPRHQLNQGTNVETVTLRGKAPQKQLSLLNRSEFQPQINTVAKSHSDSCILSSNNPPTKDLLSALLEQGSRLRNAMLISAMNTSPDTSMLLDKVPPPVADDVSRSPVLN--SPTNQCKGHREDHLLP-----------LVDTRAIQLLLGSAELSQSHCWNGLGSPPDSPAPGSDVYCSSDLNDPQYDQSLLENLFYTVPKSDVGASDFLSEDDGLEPSKTMNQSKASDRS-KVEGSREQKLKKRAAVKKSRN--------------AAMSLSVDRLALLGRVHAVRIIIEAMGVPPDSPHATPSRKIFAGKPPKPAAAKKCTFFVEYHFPVGFSKNGLGKTALITEVVRLASSKISDGVVKFQQRFVCPIEFGGAMIEHWWSSNLTFQVYAKKTPQKKPEAVGSASLPLRAVLESELLAFSRQLPVQQENGLSSLGPLKVTMELVLGNKDFTGISAKLRRSTQPAPPSAAASLDAVLPETGQGTACTNSTTCTTCTNSPQSPNKIHKETTKKTQNLVFPEPESASSVASNSSAFMVMPPS-NLVPQVNGSAKEDGLLLHVLLMVPDGKDFVFGEPEKQPSCNVYLNCKLFSTEEVTRSVVSWGTTQPVFNFSQVIPVSLSSKCLERLKNNVMIIETWNKARSPGQDQLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSDQIMMLQRLK--NEEGTLPPFSPRPAHFLDQPPVASVAMPEKQGAQLVEHHFEFHVVMVKGLMPLQATVWGEADCYVQYYFPFQDSQPSMLQGPALLENGITLKPFRTSTTLCVPDPVFNSQHHHSLLLPTEVPVQRLLLSAFSSQGLVPGGGVQFEIWCRYYYPNVRDQMVAKGTLPLSRISAMVTMQHREDIGTQNFNLPLTPRLEPSKELKSQSSGFLDVSLRYRRSPRTAEGVLAARAVSISVQIIRACGLQAAAKALAEQEPALQFSAAVGVNASVTTHLSFLPKGEQRQTRPVACSFCPEFSHHLEFPCNLVTQHCSGEACFLAELLEFAEIIFAIYHENTKSVSDITRIQSCKNYLLGVVKVPTKDLLVKRSGITGWYPVILPEDEGLHQGLEFMQKIVGGLELSVSFTHPGDRERVLEAAELLGWSFEDTPKDLVKMEEEVPATVTISTPRLWLPLHCVLLAGHKNIHKNTYCYLRYKLYNQEAFWTPLRKPKESTD-NQVLVTFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYGNDNLERPHQTDSWIGSAYVDLSRLGEKSTRTLTVSGVYPLFGRNASDLSGAALRVHVVLSPFFPHSEPSRELDSMDCSSHSESEQLPRKSDEPQLSPPCVL---QKSPASTQVHGNSTAADVCPSQQGPPELDGTFAVSILVERAMHLSLKGSPLTDRKVSVPSCCVSFATATEPSPVYTHVVENTDSPIWGFQQQSRLSKELLLDPHQTLVFKVWHKGDEERVVGFASVDLSPLLSGFQFICGWYNITDFSGECQGQIKVAISPMESLMHFKEERQARRGIETPGSLIPMFSPLSFPASTVCDAFPGPMARHIPGLPAHAAPEED-LSSPARNGTIRNQAARHEEHVQNIRRFHESLQHG-EAVLPSDGKPTTVPSTPHTSILTCLRKNLSELDEIQKYFNQKLSKPLLPFSSQSSPAVSQSQESQREPVSVRTSSRDPESQCILEKSSNLVLQVSSLISDLQTITRDSQAALTSHQARSRSRAVATLPVARDTEAVREGSTTPEEPLAGAIEASPES-LPPPAEAPSEGGGMVRESLEQTVPIMRVQSSDDTEVGPDYSDEDYEEDIIEPRTLNEITTVTDKTSPWSSFMSDMSEILSPQPNEVQREGP---SPEPFPREELKVRS----SPQKALSPH-SAQGSPSQS-VFCEGGAYEIKVED-LASTKPQLVPSLTFSEPQESTDCVEQYPPQVNQGKKPTPEILAESEAFSSEFSDSSESFEKFPLHLPSQSKREDHKKPPMDSPAVRQKQVTTGSEVSTRQKLLLPEPVVVPNFFLPPQQLEASLRMISHSPALPPPATADQDKSEATTGALAQRPCRPRPYSLPPNLPEEETRRIARIFSSQYSQKTDEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q52KB6-1", "uniprot_id": "C2CD3_MOUSE", "id": "Q52KB6-1", "name": "C2 domain-containing protein 3", "aln": "MKQRKGQ-----GPGGGRGRKKRGLSDISPSTSLPPLVEGQLRCFLKLTINKVVWKIAKPPTSVLVRVRWWGETSDGTLFCPRDALQTEPKAVRTTTRYGIRCGPKQFTSYLTDMAVLVLEVITKFDHLPVGRVQISGLAQLSPTHQINGFFTIVSPASKKLGELQVSLALEPLSETYDSYKPLPATEVTKNVLLSERELRENTESSNTQSMIPSRSCRGPAIKIDGKELAGHSSRSTTPRGKDHLYFAENSDAVKGSLCGLQQHLNQGTNVETITLRGKAPQKQLSLLNSSEFQPQISTVAKSHSDSCILSSNTPPAKDLLSALLEQGNKLRNAMLISAMNSNPDTSMLLDKVPPPMTEAIPRSSALN--SSENHFKGHSADHLLP-----------LADTGAIQLLLGSAELSQGHFWNGLGSPPDSPTPGSDEYCSSDLNDPQYDQSLLENLFYTVPKSDVGTSELPSEDDGVEPSRTMNQSKASGRS-KVVESKEQK-QKRAAVKKSRNPIDQQELSRTPGHTPAMSLSVDRLALLGRVHSVRIIVETMGVPPDSPHMTPSRKNFAGKPPKPTAAKKRTFFVEYHFPVGFSKSGLGKTALITEVVRLASSKITDGVVKFQQRFVCPVEFGGPMIEHWWDSNLIFQIYAKKTPQKKPEVIGSASLPLRAVIQSELLSFSSQLPVQQENGLSSLGPLKVTMELVLGHKDFTGISAKLSSSTQPAPVSAATSSDTILPETGQDTACTR---------NPQSSNKIHEETTKKTQNLVLPDQESANSVASNSSIFMAVPSC-NLVHQINGSNKESGLLLHVLLMVPDGKDFVFGEREKQPSCNVYLNCKLFSTEEVTRSVVSWGTAQPVFNFSQVIPVSLTSKCLERLKNNVMIIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSAQIMMLQRLK--NEEGTLPPFSPRPAHFLDQPPVASVAMPEKQGTRLMEHHFEFCVAMVKGLMPLQATVWGEADCYVQYYFPFQDSQPSVLQGPDFLENGITLKPFRTSTTLCVPDPVFNSEHHHSLLLPTDVPVQRLLLSAFSSQGLVPGGGVQFEVWCRYYYPNVRDQMVAKGTLPLSRVCAMVTMQYREDVGMQSFNLPLTSRLEHSKELKNQSSGFLDVGLRYRRSPRTAEGILAARAVSISVHIIRACGLQAAAKALAEQEPALQFSATVGVNASVTAHLSFLPKGEQRQTRPVACSFCPEFSHHIEFPCNLVTQHCSGEACFLAELLEFAEIIFAIYHENTKSVSDITSIQSCKDYLLGIVKVPTKDLLVKRSGITGWYPVILPEDKGLPQDLDLMQKIVGGLELSVSFAHPGDRERVLEAAELLGWSFESIPKDLVKKEEEVPATVTISTPRLWLPIHCVLLAGHMNIHKNTYCYLRYKLYNQEAFWTPLRKPKESTNKNQVLITFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYGNDNLERPHQTDSWIGSAYVDLSRLGEKSPRTLTISGVYPLFGRNASDLSGAALRIHVLLSPLSPHTEPARELDSMDCSSHSESEQHPRKSDALQLSPPHVL---QTSPTSTQVHGNSAAAQVCPAQEGPPELAGTFAVSILVERAMHLSLKGSPLTDRKVSVPSCCVSFATATELSPVYTHVVENTDSPIWGFHQQARLSKELLLDPHQTLVFKVWHKGDEERVVGFASVDLSPLLSGFQFICGWYNITDFSGECQGQIKVAISPMESLMHLKEERQARRGIDTPGALIPLFSALSFPASAGCDAFPRPIARHVEGQLAHTSPKEDGLSSPARNGAIRSQAARHEEHVQNIRRFHESLQHG-EAVLTSDEKLTTAPSSSHTSILTSLRKNLSELDEIQKYFSQKLSKPFLPFSSQSSPAVSQSQESQRDPVAAGTGRQDPENQCILEKSNHLVSQVSSLISDLQTLTRGSQAALTSQQARSRSRAVTTIPDAQGTEAAGEGSTTLEEPLAGAIEASTDS-LPPPVEEPSKGGGMLHESLEQTMPITRVQSIDDTEVGPDYSDEDYEEDIIEPRTLNEITTVTDRTSPWSSFMSDMSEVLSPQPTEVQREGPSC-PPEPFPREELKVKS----SPQKAVSPQ-PAQGSPSQS-GVCEGGAYKIEVED-LASAKPQPVPSLTFSEAQEGSDSVGWRASQINQVRKPMPEMLAESEAFSSEFSDSSESFETFPLHLPSQSKREDYK----DSPAVRQKQVPTGSEVSTRQTLLLPEPVVVPNFFLPPQQLEASLRMISHSPGLPPAATTDQDKSEATRGALAQRPCRPRPYSIPPNLPEEETRRIARIFSSQYSKKTEET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4AC94-5", "uniprot_id": "C2CD3_HUMAN", "id": "Q4AC94-5", "name": "C2 domain-containing protein 3", "aln": "MKQRKGQ-----GSGGSRGRKKRGLSDISPSTSLPPLVEGQLRCFLKLTVNRVIWKIAKPPTCVLVRVRWWGETSDGTLFCPRDALQTEPKAVRTTTRYAIRCGPKQFTSYLTDMAVLVLEVITKLDGLPIGRVQINGLAQLSPTHQINGFFTIVSSTSKKLGELQVSLALEPLSETYDSYHPLPTTDMTENVLLSKQGFRENTEPSSTQFQVPSRPRDIHTIKIDGKELAANSSRSTTPRGKDHVCFAENPDTIKDSSFGLQHSLNSGQSLESVTLKGRAPRKQMSLLNSSEFQPQIRTVAKSHSDSCILSSNNLPTKDLLSALLEQGNKLRNAMVISAMKSSPETSMLLDQVHPPINEDSLRASTQIRAFSRNRFKDHIEDHLLPSTENTFWRHDTKADTRAIQLLLGSAELSQGNFWDGLGSPPDSPSPGSDVYCISELNDPQYDQSLLENLFYTAPKSDTSISDFLSEEDDIVPSKKISQSTALARSSKVLESSDHKLKKRSAGKRNRNLVEQQMLSETPEDAQTMTLSVDRLALLGRTHSVRIIIETMGVPPDSPQMTPGKKSYAGPPPKVTTAKKRTFFVEYHFPVGFSESGLGKTALITEVVRLASSKITDGKVKFQQRFVFPVQFGGPMIEHWWNSNLTFQIYVKKTPQKKPEVIGSVSLSLRAVIQSELLSFSDQLPVQQENGQSPFGPLKVTMELITDNKDFTGINTKLSGNTHYTPLCAPTSPNKALPELNQDMTCTK---------NPQNLNQIHEETAKKAQNLVLPNRKSPSPVAPHPSTFVATPASHNLVNQTNGTTKESALLLHVLLMVPDGKDFISGESEKQSPCNVYLNCKLFSTEEVTRSVIAWGTTQPVFNFSQVIPVSLSSKYLERLKNNVMVIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDAKISRLLLDAQYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSNQIMALQRLK--NEEGTLPPFSPRPAHFLDQPTAASVAMAEDRGNGLMEHCFEIHIEMVKGLAPLQATVWGEADCYVQYYFPVQHSQSSVLKGPEFLENGITLKPFRTATTLCVPDPIFNSEHHHSLLLPAEVPVQRLLLSAFSAQGLVPGGGVQFEIWCRYYYPNVRDQKVAKGTLPLSRICAMVTTQHREDVGIQTFNLPLTPRIENRKELRNQSSGLLDVGLRYRRSPRTAEGVLAARTVSISVQIIRACGLQAAAKALAEREPALQFSATVGVNASVTTHLSFLPQGEQRRTHPVACSFCPEFSHHVEFTCNLVTQHCSGEACFLAELLEFAEVIFAVYHENTKSASDIISIESCKEYLLGVVKVPTKELLIKRSGITGWYPIILPEDGGLPHGLELMQKIVGGLELSISFTHRGDRERVLEAAEHLGWSFENSLKDFVRMDEGEPATVTISTPRLWLPIHCVLLAGHNHIHKNTYCYLRYKFYDHEAFWTPLKKPKESVNKKQIMVTFKASKRAEVTRGPSLLWYFREERLEIQVWRAYGNDSVERPHQTDSWIGSAYVDLARLGERSARTLTVSGVYPLFGRNASNLSGAALRVHVVLSSLSSHLEPTHELDSMDCSSHSESEQLPRRNDEVQLSPPEVISCHQKSPASTQVPCSSTTAEVRLTQEGPADLDGTFAVSILVERAMHLSLKGSPLTERKVSIPSCCVSFATADESSPVYTQVVENTDSPIWNFQQQSRLSKELLLDPQQTLVFKVWHKGDEERVIGFASVDLSPLLSGFQFVCGWYNITDFSGECQGQIKVAVSPLESLIHFKEERQARRGVETSKSLIPIYSPFSFPASDTYAAFSSHMARQTLDQLAHASSKELDFSSPGRSDTTRSQASRHEEHVQNIRRFHESLHLQGEAPLPCDDKLTTSPLSSQTSILTSLRKNLSELDQIQRYFRQKLTKPFLPLSPQTQTAISQHQESCRDHLGPGASSLDPGSQCILEKSSNLVLQVSSLITDLQTITRDSQAALSSHRARSRSNKATTLPDAQDTEALQERCTMPDEPLVRAPDKGTDSPSPPPLEETSNGGRMLHESLRHAVPITRMQSSEDTEAGPAYSDEDYEEDIIEPRTLNEITTVTDKTSPWSSVISDTSEVISPQPDEVQREGPSCPSPGPFCREELMVKSSFLSSPERAVNPHLPRQGSPSQSLVACECEASKARVGGESASANPQPIPCPTLSGAQQSSTFVGWSSPQTDQNKEPKSEAPAENEAATSELGDSADSFKKLPLNLASQSRRENHKGPPIDSSDIRQRQVTTGSETSTKQSLLLPGPIVVPNFFLPPQQLEASLRMLSLSATLPPAATTDQDKSEATRGALSQRPCRPRPNSLPLNLPEEETLRIARIFSSQYSQKD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPD7-1", "uniprot_id": "Q9VPD7_DROME", "id": "Q9VPD7-1", "name": "C2 domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAMKKLDADLVALFATAASAEPLKIR----KQQEVLWPGAEPE---QTAQESEDDELVMTPELFRSCNALQLHLEALTLQP--------EGTQRMELVQNEVRPIFTVECQLSGDLIR-----------------------------------------------------------KVPRQPMFHIMQFESEKFQSLTQCTRFGQTAQRQVDMEDKSLQDPEQSAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------HVDITVWWREPGTCLNEMLGMGRLELRELYRASLLEQCKCIAIRRRD--VHLGSVYLKISLLQNLN------------------GSPEQPQQQQQQPGQKNESGN------------------KAAVNCNSKAVLTPPQPPAPPPPPPQANNNSKAILECINFMAETNKVR--LLRGYLYAGELRQLTAGGS--KTACQELSLEPFWQPQPLLSKLTDGGS----FELQEQFAIINDERFLQSVERQQLVMELR---------PLGGVVRLPLHQFFIAYRDSSITNHLCKGKLPVISIDGWAPIVSAENKTPLGELKVLLAIGSESQIAQLKQLRGFDHDNNQVPAPSRTTDLLD-----------------------------------------------------------------MLQNAIAAPTPNIAGPVMPPPPAPPAPSTFSFQLRIVGAAG----------------------------------------------------------------LPLNPGYGKSKKQVKR---------------------------------------QSAAKRFPPNEPPNTYVTFQAISCNSQTYKSHEG---------------------LVYATPIVPKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKPQWLSKFRVDVSRDYRSNPQKLFILKLWKKAVVSPNGITEPSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------HEDAIIGFAALNLNQKQAGGGFPSGWHNIVDFNGRVTGGIEAHVEPISPSVDT-----------------------------------------------------------------------------VIDQFEKSMELG------------------HLQLGQAIKRKYTELEEISQRLRSRLVDVTG--------------------------------------------------ETLKFPEFDVDSALDSWQQEGD-----------------------DDDLAEDFERSLRTPTPPGSPTPS-----------TSTAAQNLRNSNGQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* . : . . *.:.:: ::* * :* : *. :*..*. :::.: : : *. ** . : . .:: ::* * . : * . : :::. :::. . * ..: :.. .: :: .. :: : :: ::. * :* * ** : .:.** . :.:::.: :*.: :.:.*: . : :. . : : .* . . : :.: .: *:. :.. . .. .. . : : : * **: * . : ::: * :..*: ::..: : .: *: *::.: :.: .: *: ::.: :::* * *:*:******:::::*..*:. * ..: **:::*.: *::.. . *.*:*:**:**. ** *::*: :.:.. * ..*.:.:** :*:*.*: . . : .: * * : .*: * .. ***.. *: .: *:*** :. .**. : : .:... :: *. : :. :*.: . .*:.. **::* . ..:.* : :: ....:: .: .*: ::***:::*. :* * .**:**.**.*. * *:. :.*:.. :. * :*.:*:. : .: .:::: :**::*.: : .:* . *: . ::** * : .. :: *. : . : ** .* : . .::. :. * ", "identical_positions": 124, "similar_positions": 330, "identity": "5.23%" }, { "cls_id": "homologset.agr.MGI:2142174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQT5-1", "uniprot_id": "IDHG2_RAT", "id": "Q4QQT5-1", "name": "Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial", "aln": "MLAAGSCSVRTILQPALLLGHSREVVCELVTSFRN--FCSKYSVPPSPKYGGKHTVTMIPGD-GIGPELMVHVKRIFRSNCVPVEFEEVWATSTS-SEEEINNALMAIRRNRITLKGNIATNHHLPAKYKSHNTKFRTALDLYASVVHFKTFPGVETRHKDIDILVVRENTEGEYTNLEHESVRGVVESLKIVTKTKSVRIADYAFRLAQKMGRKKVTVVHKANIMKLGDGLFLQCCKDVAAH-YPQITLESMIIDNTAMQLVSKPQQFDVMLMPNLYGNIINSVCTGLVGGSGIVPGANYGDSYAIFETGSKEIGQDLAHRNIANPVAMLLTSCIMLDYLDLQLYAAHIRSAVMASLQNKSICTPDIGGQGTTAGVVEYILDHMKDQNSGCQPRFFLST-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPC6-1", "uniprot_id": "IDHG2_MOUSE", "id": "Q8BPC6-1", "name": "Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial", "aln": "MLAVTSCSMKTVLQYAVFLGHSREVVCELVTSFRS--FCSHCAVPPSPKYGGRHTVAMIPGD-GIGPELMVHVKKIFRSNCVPVDFEEVWVTSTS-NEEEINNALMAIRRNRVALKGNIATNHNLPARYKSHNTKFRTILDLYASVVHFKTFPGVMTRHKDIDILVVRENTEGEYTNLEHESVKGVVESLKIVTKTKSVRIADYAFKLAQKMGRKKVTVVHKANIMKLGDGLFLQCCKDVAAH-YPQITLESMIIDNTTMQLVSKPQQFDVMVMPNLYGNIINSICTGLVGGSGIVPGANYGDSYAIFEMGSKEIGKDLAHRNIANPVAMLLTSCIMLDYLDLQPYATHIRSAVMASLQNKAVCTPDIGGQGNTASTVEYILHHMKEQTSGCHPNFFLQFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QZA4-1", "uniprot_id": "F1QZA4_DANRE", "id": "F1QZA4-1", "name": "Isocitrate dehydrogenase [NAD] subunit, mitochondrial", "aln": "MMATLTKALKPILG--RQLGNTAKVFGAGVVSQRGKPTYSGRIIPPPAKYGGRHTVTLIPGD-GIGPELLNHVRELFRFSCVPVDFEVVHVNSSSTSEDDISNAIMAIRRNGVALKGNIETNHTMPPNHKSRNNLLRTSLDLYANVMHCQSLPGVQTRHKNIDIIIIRENTEGEYSSLEHESASGVVECLKIITRNNSLRIADYAFKLAREKGRRRVTAVHKANIMKLGDGLFLQCCKEVASG-YPDIEFENMIVDNTTMQLVSKPYQFDVMVMPNLYGNVVSNVCAGLVGGPGLVPGANYGRDYAVFETATRNTGKSIANRNIANPTAMLLASCLMLDHLKLHDYANMIRSAILTTMNETRLHTVDIGGQGTTSEVVQSIMRIIQ--SGGPLTKEI----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28834-1", "uniprot_id": "IDH1_YEAST", "id": "P28834-1", "name": "Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial", "aln": "MLNRT---------------IAKRTLATAAQAERT----------LPKKYGGRFTVTLIPGD-GVGKEITDSVRTIFEAENIPIDWETINIKQTD-HKEGVYEAVESLKRNKIGLKGLWHTPADQTG-HGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZAD2-1", "uniprot_id": "A1ZAD2_DROME", "id": "A1ZAD2-1", "name": "Isopropylmalate dehydrogenase-like domain-containing protein", "aln": "MLRCPKVTQSMLARISVRHFADEIHGSVRAAYAKGDARADPVNVLPKSKYGGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVIEAGQDD-------EYFHSVLRN----RTAVHVDNQADAEAKQKALKICNDLDLYVFKTRTRSFPGFKCRFPGVDIQLIGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISDGSLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCGGANLFSAVEIGDHHAVFKP--LQTKLSLTNYANLSAYGIVSTIVDLFQHLGHDKCADALWCELKRTMDEG-IRTKEFGGQDTGEYVICNIINQLRCRALGK---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . : **** **:::.* :* : * :: . :*:: : : . . : . :: ** : . . : . **:*. ::: *. * .:*: :: :*. * :. **:... ****.*.:::: . : :** * : .*: ** ::**: :.** : : : : .. : :::: : :::* ** :. .. *...:. : :.: **..:....: * :*:*: . .: .. .:: : ::::* . * : : :: : * ::**... *: : ", "identical_positions": 53, "similar_positions": 129, "identity": "13.22%" }, { "cls_id": "homologset.agr.MGI:2142186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LXY1-1", "uniprot_id": "A0ABK0LXY1_RAT", "id": "A0ABK0LXY1-1", "name": "", "aln": "MGAIGAVRCSSSRSLGPSGNVRPPCFYPSPKPPPPPHASSRFPLPPPSPRLPVPVSSAAGASQGAGANRRRRRRPRRRRSEPGRSLPGRYMVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLQAALAALSRGSLTPSSSS----------------SSSSPSRDTAETPCPLTSHVDSDSSSSHSRQE-----TPPTAV-APIATVESATAFPPATPPQRRRSS-----AQSYPPLLPFTGIPE----PSESLAGAGSQG--------RGGRGYEDYRRSGPPPPPLALST--------------CVVRFAKTGA---LRGAALGPPVSLPAPLTEAAPPALP-ARP--PPGPGPTPAPAKASP--------------------------------------EAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGD-FSDPCACEP-----GHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P6N5-1", "uniprot_id": "SPRE3_MOUSE", "id": "Q6P6N5-1", "name": "Sprouty-related, EVH1 domain-containing protein 3", "aln": "------------------------------------------------------------------------------------------MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALSRGSLTPSSSS----------------SSSSPSQDTAETPCPLTSHVDSDSSSSHSRQE-----TPPT---APIATVESAAAFPLATRPQRRRSS-----AQSYPPLLPFTGIPE----PSESLAGAGSQG--------WGSRGYEDYRRSGPPPPPLALST--------------CVVRFAKTGA---LRGAALGPPVSLPAPLTEAAPPAPP-ARP--PPGPGPTPAPAKASP--------------------------------------EAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGD-FSDPCACEP-----GHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2MJR0-1", "uniprot_id": "SPRE3_HUMAN", "id": "Q2MJR0-1", "name": "Sprouty-related, EVH1 domain-containing protein 3", "aln": "------------------------------------------------------------------------------------------MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTPSSSS----------------SSSSPSQDTAETPCPLTSHVDSDSSSSHSRQE-----TPPSAAAAPIITMESASGFGPTTPPQRRRSS-----AQSYPPLLPFTGIPE----PSEPLAGAGGLG--------WGGRGYEDYRRSGPP-APLALST--------------CVVRFAKTGA---LRGAALGPPAALPAPLTEAAPPAPP-ARP--PPGPGPSSAPAKASP--------------------------------------EAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGD-FSDPCACEP-----GHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P152-1", "uniprot_id": "A0A8M9P152_DANRE", "id": "A0A8M9P152-1", "name": "", "aln": "-------------------------------------------------------MMMLPVENGCCILEPIRNHMKVDRERQENESSEHKDVRVRAVVMTRDDSSGGWVPLGGGGLSHVIICKGRSS--EGRGRR-EYVIRGERLRDRAPVLECAIQKGLVYNKVNPIFHHWRVEERKFGLTFQSPADAISFERGLQSVLEKLDRGSDSPSSSTPEEGDTEDDGQASHTGSESSSNSRKEMLPKPITIVTSESSSTCFVRPSEEFAYGNRTQTPAQIHTRPSQHQLTQVTAVLNPPSPPPPPPAPPTPPAAPPAASPLSPLSPTISLLEEGDLRSLDPCKDLWGTRGYEDYRRAGATRTKVGGLTGGVVVGGGQDKSELCVVRFEKELAGVGTTGCEVTVMLDTKGSQRNSSPTCMPNAVPGVPSASGSPQETGKSSPSPCCIHTSLATPRSRTRKRGAGGGEAISPDDDSSCPQGSSSCSSRCVYCRSVFSASENGRG-RCRDAPDPALHCLRQWTCVWCAESLLYHCMSDSEGE-FWEPCSCEDSMGGRPHPLCCARWMALLALSLFVPCMCCYLPLRACLRCGERCGC--CGGKHKAVR---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG11-1", "uniprot_id": "A0A0B4KG11_DROME", "id": "A0A0B4KG11-1", "name": "", "aln": "---------------------------------------------------------------------------------MTEGHESDFLVTVRAQVMTRDESTEGWLPLAGGGLANVSIR--KRARLSPLASGHDYIIYGQRISDQSVILSCVINRDLKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDGLAKSNPTIICP-----------PLTKYDSVGEDDVFMTLDLPVESESLQKIHSSPEG----SEKSHKSVSNNSDSEKLPPPPIHYISTDKTS-----ATTSPPDAPPASAAP-------SPATAGQIAASENYSYVTLTAVHHDYNYPVVDQPVGAQVLN---------------ARRESISALKKRNALEAAQAMAAAQTAAGGGLACRD-------GGSGKPLHKPNVSD------------------------------------ILKKETRLRCRYCHELYSEDFNRRG-ACEYAPDAFRSGYECISGMGCARCMIYHCMSDAEGETAQHPCDCSAS-----EAGCSKRWLGLAILSLFVPCLWCYPPLRACHLAGIHCGL--CGGQHKPHVXHLEARLQGQHDDDPRPRSEFHYHHSEQSIMNSAKRPWGAKQKQSQQSQQSQRHFYNWELSHSLGAPQHQTPPYLMQSTGRKAPQNDYGRLLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *** **:**:*: **:*:.****::* : : : . . .*:* *:*: *: *.*.:. .* * ** * **** . : *****:.*:* *::.: . * * ....: :. .. ... .. . . : . : . :. * . ** * :. . . * :.**. . . . .* . * . . .. .. ..* . : * . . ** :*: :: : ** * ***. . : : **..::***:**:**: .** *. .. . ** .* *** ***: ** ***** . :** ***:*: ", "identical_positions": 97, "similar_positions": 107, "identity": "13.96%" }, { "cls_id": "homologset.agr.MGI:2142195", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKE0-1", "uniprot_id": "A0A8I6GKE0_RAT", "id": "A0A8I6GKE0-1", "name": "", "aln": "MAANVGDQRTADWSSQYSMVAGASRENGMETPMHENPEWEKARQALASISKAGAAS-SSKASSSGPVASAQYVSQAEASALQQQQQQYYQWYQQYN-----YAYPYSYYYPMSMYQSYSSPSQYGMASSYGSATA---QQPSAPQHQGTLN------QPPVPGMDES-----MAYQASPQQLPAAQPPQP-------------------SNPQHGTHSLNNGPQSG---------TAPTTQHNQAGAPTGQTYGPHSYSEPAKP------KKGQQLWTRMKPAPGTGGLKFNIQKRPFAVTNQSFSSNSEGQHSGFGPQPNSEK-TQNHSGPSGRGN--LSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGQSWAWSLSCTTVAELPGLTREPVAESPKKKRWEAPSSLHPSRGAGSVTRGGGAQSQRGTPGAGGAGRARGSSFAKFGN-RNVFMKDNSSSSSTDSRSRSSSRSPTRHFR--------RSDSHSDS----DSSYSGNECHPVGRRNPPP-KGRG-----GRGAHMDRGRGR--AQRGKR--HDLAPTKRSRKK-------MAALECEDPERELKKQKRAARFQHGHSRRLRLEP-LVLQMSNLESSGADPD--------------------------WQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKSHWKEK-QDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAEN--LAGNVGEFTAYRILYYIFTKNSGDITTELAYLTRE----MKADPCVSHALALRAAWALGNYHRFFKLYCHAPCMSGYLVDKFADRERKAALKAMIKTYVALHSAAFCAVALPHPLHILVSLQLLCWSPLPIPCSHPWPSLLSSSATFSSRFSPTVLTSLLLVSCPVLPCTPVTSVWNLVYFPFSGSLPAARCCSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBY3-1", "uniprot_id": "LENG8_MOUSE", "id": "Q8CBY3-1", "name": "Leukocyte receptor cluster member 8 homolog", "aln": "MAANVGDQRAADWSSQYSMVTGNSRENGMETPMHENPEWEKARQALASISKAGATS-SSKASSSGPVASAQYVSQAEASALQQQQQQYYQWYQQYN-----YAYPYSYYYPMSMYQSYGSPSQYGMASSYGSATA---QQPSAPQHQGTLN------QPPVPGMDES-----MAYQASPQQLPAAQPPQP-------------------SNSQHGTHSLSNGPQPG---------TAPSTQHSQAGAPTGQAYGPHSYSEPAKP------KKGQQLWTRMKPAPGTGGLKFNIQKRPFAVTSQSFSSNSEGQHSSFGPQPNSEN-TQNRSGPSGRGN--LSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPG-----------------LTREPVAESPKKKRWEAPSSLHPSRGAGSVTRGGGAQSQRGTPGAGGAGRARGSSFTKFGN-RNVFMKDNSSSSSTDSRSRSSSRSPTRHFR--------RSDSHSDS----DSSYSGNECHPVGRRNPPP-KGRG-----GRGAHMDRGRGR--AQRGKR--HDLAPTKRSRKK-------MAALECEDPERELKKQKRAARFQHGHSRRLRLEP-LVLQMSNLESSGADPD--------------------------WQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKSHWKEK-QDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAEN--LAGNVGEFTAYRILYYIFTKNSGDITTELAYLTRE----MKADPCVAHALALRAAWALGNYHRFFRLYCHAPCMSGYLVDKFADRERKAALKAMIKTYVALHSAAFCAVALPRPLRILVSLQLLCWSPLPVPCS-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PV6-2", "uniprot_id": "LENG8_HUMAN", "id": "Q96PV6-2", "name": "Leukocyte receptor cluster member 8", "aln": "MAANVGDQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQ--YYQWYQQYN-----YAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATP---QQPSAPQHQGTLN------QPPVPGMDES-----MSYQAPPQQLPSAQPPQP-------------------SNPPHGAHTLNSGPQPG---------TAPATQHSQAGPATGQAYGPHTYTEPAKP------KKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEK-VQNHSGSSARGN--LSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPG-----------------LTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGN-RNVFMKDNSSSSSTDSRSRSSSRSPTRHFR--------RSDSHSDS----DSSYSGNECHPVGRRNPPP-KGRG-----GRGAHMDRGRGR--AQRGKR--HDLAPTKRSRKK-------MAALECEDPERELKKQKRAARFQHGHSRRLRLEP-LVLQMSSLESSGADPD--------------------------WQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKCHWKEK-QDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAEN--LPGNVGEFTAYRILYYIFTKNSGDITTELAYLTRE----LKADPCVAHALALRTAWALGNYHRFFRLYCHAPCMSGYLVDKFADRERKVALKAMIKTFRPALPVSYLQAELAFEG---EAACRAFLEPLGLAYTGP------DNSSIDCRLSLAQLSAF------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QNR8-1", "uniprot_id": "LENG8_DANRE", "id": "A4QNR8-1", "name": "Leukocyte receptor cluster member 8 homolog", "aln": "MAANAAQQAPTQNWPYGNNSSG-------EGPVHENPEWEKARQALASISKSQNST--KPSTNQTTQQAGQYQAAVTDSSAMQQQQYYQQWYQQNQQQYAGYPYPYNYYYPMPPYGGPYPPGQYGVPGGYQTPTTPTGQAPSMPTMEDQSSNYPP--QPPPPATPQPPPQSPTSSDQPPPPPPPPIPPQPNAQYPRPPSQTPYSPNGVLPYSPTDSNPMMRGYNPGQIRPGYQGYQTPVYQPHQQQAPAPGLYGGAGRVDAKKPNNSNMNKGGQQLWQRMKQAPGTGAVKFNIPKRPYVMSNQNFPPGEQGPGLAPPTATNPSSGSTSATSSASTGG--AQTRPQDWPQAMKEYVQRCFTACESEEDKDRTEKMLKDLLQSRLQDGSAYTIDWNREPLPD------------------------LKPKQSRWEVMPQLS----------------QENSIGRGGATRGRGG--ARLGNYRNVFSQRSPSSSSSGS-SRSSSRSPSPHSRHRDRSRHHRSDSGSQS----DGSMSSDLRLSLTRRQQKGGRGRGAERERGRGAAGERGRGRGKANRGRRNMEDLASGVGKKRKG-----GNAGLDFHDPNREAKKQSRAARFHT----KLRTEP-LVLNINVFDLPNGTQEG-----------------------LSWDDCPIVGTCQDITKNYLRLTCAPDPSTVRPVPVLRKSLIAVKAHWKSN-QDYVYACEQMKSIRQDLTVQGVRTDFTVEVYETHARIALEKGDHEEFNQCQTQLKALYKDC--PSDNVGEFTAYRLIYYIFTKNSGDLTTELVYLTTE----LRADPCVAHALELRTAWALGNFHRFFRLYQKAPRMAAYLIDKFVERERNIALRAILKSFRPSVSVEYVQSSLAFPD---LDTCLAFLTGLGISFTPS------DPSKIDCKVSSASLTTS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKP5-1", "uniprot_id": "Q9VKP5_DROME", "id": "Q9VKP5-1", "name": "PCI domain-containing protein", "aln": "MSDAMSAPPP------------------LIPQLQEMQQQQQQSANPAQLAQQWSNYAWYANQNAAYQQQYQQYYQYYVRYQQQQQQQVTSTVSTSN-APPGFSNALAAPPPLPSGPPPPPPPQIGQPPGQNKQQQQQQQQQQLQQQQQQQQQQQQQQQKNFGGIRFNLNLNQKRLAGAPNPLQQQQQQQHQQQ---------------QHQQQQQVMQLYNNNNSNKKKR-----KRNNKNKNFEQSTYSNPFANQTPATPQAP-------PPPIISASDVGVPINPDLSKPPPPLPLAIVAPTENPQHQKQQQQEHMAAQRAGEATSQTSNFKRPNSFQMASSDSWPNSLNQYVARCYSKCNTDLDKDQIDICLKGKIIAAANRNELWTRDWDNEPMPTVYSERD---------GIDVVLSNVPPPQQQRSNYFQKKQEQERERERDREADKSPAKGSTGIVNQFKQKGNQFNKASSSYGSHHSSSSKYSRSRSRSPSSSNSLKYSSKKRYSRSRSRSRSRSRSPRSRSCSRSSDASSPPARKIIRKSGSNESLNFIPLTANLSRKQQKMLMKKGKR-AAAMASAQMKKKDTPHFYSNQSSVGGAVDDDTARLQQRAARFSQQGSSSAKKSV-VAIASSPFGLTTAKNKKKMVQQHQQHQRSAFYEDTEAASGIDLLDLHIVGTCRDLEKSFLRLTKAPSPSEVRPVEVLTHSLVNVKGKWRAN-QDYHYACDQLKSIRQDLTVQGIRDQFTVEVYETHARIAMEKGDHEEFNQCQTQLKMLYMEIGGKNANALEFTAYRILYYIFTKNTLDITTVMRSITAD----QRENPVIAHALQFRSAWSLGNYCKLFSLYRTAPLMSGHMIEWFLERERKAALRVIIKSYRPNISVDYITKILAFDS---SEKCKEWLDTFSLPYAADG-------AQVDCKNAAAIAI--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12049-1", "uniprot_id": "THP3_YEAST", "id": "Q12049-1", "name": "Protein THP3", "aln": "-----------------------------------------------------------------------------------------------------------------------------MQNPYGHFTN---------------------------------------------------------------------------NTTEDREASSQGGPFG---------QSLNRPLDYAGSFPSLTYNNNNFIANQQP-----------------------SLPLPEPRLSWNNVNQVSNPLMVTPLPG---------------------------------------------------LQKRMNKNIKKKLPRVSKKASALSNGVSGNVMSN--------------------------------------------------------SNIVGHGAVGSASGWKVEMGGS----------------------------------------------------------------------------------------------------------------------------------DELERRKRRAERFSQGPSATTNSNDNLNEDFANLNAISSKSHQYD------------------------KKIHVVGRCQTLEKSYLRLTSEPNPDLIRPPNILQKMYCLLMDKYQSKTATYTYLCDQFKSMRQDLRVQMIENSFTIKVYQTHARIALENGDLGEFNQCQNRIMALFENPTIPKKSYSEFICYSVLYSMLTEDYPSISHLKLKLIDDGSSEILEDEHVKMIFELSDMKLVGNYHYFMKNYLKLHKFEKCLINSFLNLEKLIFLTIICKSYN-QVNLDFVKSEFNFNSIEETTNFLNEQNLTEFILNKQITDSNGKSSNIKILNTKGCRVQLIQNYMKSKKIDIKGQK--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : * : . . :.: : :* : : . : . . : :. . * * .. : : : ** ** . . : : . . . :** * : * :**** *.*. :** :* : : ::: : * : *:*:**:**** ** :. .**::**:******:*:** ******.:: *: : . ** .* ::* ::*:: .:: : : : : : : :**: :: * : ::: * : *: * : *:: : : . ", "identical_positions": 64, "similar_positions": 97, "identity": "6.5%" }, { "cls_id": "homologset.agr.MGI:2142208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHL6-1", "uniprot_id": "FAP24_MOUSE", "id": "Q8BHL6-1", "name": "Fanconi anemia core complex-associated protein 24", "aln": "MERNPPDGTGPVHVPLGHIVASEKWRGSQLAQEMQGKVRLIFEEGLASADFYLSSKSCILYVTEADLVAGHGYRKRLARFRNSSHLQGIIIVEKTQMSEQYFPAVQKFTVLDLGMVLLPVASQSEASCLIIHLVQEQTREPSKNPFLRKKRS-MLSELSLVQTVQQIPGVGKVKAPLLLQKFPSIQQLSNASVQELEEVVGPAAAQQIHTFFTQPKRQQPRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZE71-1", "uniprot_id": "D3ZE71_RAT", "id": "D3ZE71-1", "name": "Fanconi anemia core complex-associated protein 24", "aln": "MERNPPGGTGPVHVPLGHIVANEKWRGSQLAQELQGKVRLIFEEGLASTDFYLSSKSCILYITEADLVAGHGYKKRLARFRNSAHLQGIVIVEKTQMSEQYFPAAQKFTVLDLGMVLLPVASQSEASCLIFQLVQEQTREPSKNPFLRKKRS-MLSESSLVQTVQQIPGVGKVKAPLLLQKFPSIQQLSNASTQELEEVVGRTVAQQIHTFFTQPKRQQSWH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BTP7-1", "uniprot_id": "FAP24_HUMAN", "id": "Q9BTP7-1", "name": "Fanconi anemia core complex-associated protein 24", "aln": "MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLT-PDFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:***..*************.***********:***::****:**: .*****.:.****:********:**:***.*.*** :*:**::****:******** ****************** *****:::******:******:* ***: :*** **::****************************** ***:*** :.*****:*****: ", "identical_positions": 169, "similar_positions": 37, "identity": "76.13%" }, { "cls_id": "homologset.agr.MGI:2142227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B1B9-1", "uniprot_id": "A0A8I6B1B9_RAT", "id": "A0A8I6B1B9-1", "name": "Leucine-rich repeat serine/threonine-protein kinase 1", "aln": "--------------------------------------------------------MNQRR----WNIP-EGLQIP---------GAEDMGSKLSLPGGNSPVQSPNMEEIHTAYKQRNLSRARDLLREVCEE-----SESPQEKGQLLSISAAHGDLETVRFLLTEKRVELPMEPTDDNPAVVAAHFGHAEVVHELLESLSGPCASQRLLNWM-LALACQRGHLEVVKLLVLTHGADPENYAVRKNEFPVIVRLP-----------------------------------------------------------------------------------------------------------LYAAIKAGNEDIAIFLLRHGAY------------------------------------------------------------------FCSYILLDSPDPSK-----------------HLLRKYFIEASALPSSCPGKTALCVKWSHLKLPWVDLDWLLD------------------ISCQITELDLSANCLSSLPSIIPWGLINLKKLNLSNNHLGELPCVQSSDEIICSRLVEIDISSNKLSHLPPGFLHLSKLERLTASKNYLERLFEEENATNWIGLRKLEELDLADNRLTELPVQFMHSFKSLTNLNVSRNSLKSFPDP----------------------------------------------WSCPLKCCKASKNALESLPDKMAVFWKNHLRDVDFSENSLKAVPLGVFQLDALMFLRLQGNLLLSLPHHEKWTCRQLKTLDLSRNQLGKNED-------------GLKTKRISLFTTRGRQR-----------------------SGTETASVLEFP-------------AFLSESLEVLCLNDNHLDAVPPSVCLLKNLSELYLGNNPGLRELPPELGQLGNLWQLDIEDLNIGN---VPAEVRKEGPKATLSFLRAQLRKAEKCKLMKMILVGPPRQGKSTLLEILQTGKAPQPAHSEATVRTTK------------------------------------WELQRPAGSKAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKNLEGQEGLRQLIFHVTCNMKDVGSTIGCQKLAGRLIPRSYISLQEAVLAEQQRRSLEDQVQYLTDRQLEQLVEQTP----GNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIRAEDLRMLLVGTGFTQQTEEQYFQ-FLAKFEIALPVANDSYLLPHLLPS----------------------------------------KPGLDTHSMRHPMANTIQRVFKMSFVPVGFWQRFIARMLIS-----------LAEMDLQLFENKKNTKSRNRK----------------VTIYSFTGNQRNRCSTFRVRRNQTIYWQEGLLVTFDGG-------YLSVESSDVNWKKKKSGG--IKIVCQSEMRDFSAMAFITDHVNSLIDQWFPALT---ATESDGTPLMEQYVPCP--VCEASWAQHADPNER------------------------------------------------------------------------------------------SESVQYFDMEDCVLTAIEGNFISCPRHPDLPVPLQELVPELFMTDFPARLFLE-NSKLEHTEGENSILGQGGSGTVIYQAQYQGQPVAVKRFHIKKFKNSANAPADTMLRHLR-------AMDAMKNFSDFRQEASMLHALQHPCIVSLIGISIHPLCFALELAPLGSLNTVLSENAKDSSFMPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSL-------SVKELINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIR---PRIVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIRPVLGQPEEVQFYRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYMLPCGKQSSFFSSQSQEYTVVFWDGKEESRNYTVVNTEKGLLEVQRMTCPGMKLSCQLKVQSSVWLATEDQKIYIYSLKGMCPLSMPQQALDTPAVVTCFLAVPVIKKNSFLVLAGLADGLVAVFSMARGTPKESCSYLCSHTANRSKFCIPDEDSRQNPYPVRAMEVVNSGSEVWYSNGPGLLIIDCAILDISRRLEPYAAPSVVTSLVCSSDCRGEETVWCLDDKGNSLVMYHSATYQLCARYFCGDPSPLRDTFSVQPSVPESPIR-HITTSKEPEEECIADVSIMYSEELGMQILTHQDSLTDYCSVSSYSSTP-HPDPKSPTSLPSSLTSYSSVPFSANYEDPDRLQEPSVTPDRTEHDLSPMDGETFSQHLQAVKVLAVQDLIWVPRHGGDIIVIGLEKDSGAQRGRVIAVLKARELNPHGVLVDAAVVAKDTVVCGFANENTEWCLAVWRGWGAREFDIFYQSYEELGRLEACPRKRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHC2-1", "uniprot_id": "LRRK1_MOUSE", "id": "Q3UHC2-1", "name": "Leucine-rich repeat serine/threonine-protein kinase 1", "aln": "-----------------------------------------------------MAGTSQRPPSMYWCVGTEGLAVCPGPAMETHNGAEDMGSKLSLPGGSSTVQCPSMEEIHTAYKQRNLSRARDLLRGVCEE-----SESSQEKGQLLSIAAAHGDLETVQFLLTEKRVELPTEPTDDNPAVVAAHFGHAEVVRELLESLPGPCTPQRLLNWM-LALACQRGHLEVVKLLVLTHGADPENYAVRKNEFPVIVRLP-----------------------------------------------------------------------------------------------------------LYAAIKAGNEDIAIFLLRHGAY------------------------------------------------------------------FCSYILLDSPEPSK-----------------HLLRKYFIEASALPSSYPGKIALRVKWSHLKLPWVDLDWLLD------------------ISCQITELDLSANCLPSLPSIIPWGLINLKKLNLSNNQLGELPCVQSSDEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNYLERLFEEENATNWIGLRKLQELDLADNRLTELPVQFMHSFKSLTSLNVSRNNLKSFPDP----------------------------------------------WSCPLKCCKASKNALESLPDKMAVFWKSHLRDADFSENSLKEVPLGLFQLDALMFLRLQGNQLLSLPPQEKWTCTQLKTLDLSRNQLGKNED-------------GLKTKRISLFTTRGRQR-----------------------SGTETASMLEFP-------------AFLSESLEVLCLNDNHLDAVPPSVCLLKNLSELYLGNNPGLRELPPELGQLGNLWQLDIEDLNISN---VPAEVRKEGPKATLSFLRAQLRKAEKCKLMKMILVGPPRQGKSTLLEILQTGKAPQLAHSEATIRTTK------------------------------------WELQRPAGSKAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKNLEGQEGLRQLIFHVTCNMKDVGSTIGCQKLAGRLIPRSYISLQEAVLAEQQRRSLGDQVQYLTDRQLDQLVEQTP----GNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIQAEDLRMLLVGTGFTQQTEEQYFQ-FLAKFEIALPVANDSYLLPHLLPS----------------------------------------KPGLDTHSMRHPMANTIQRVFKMSFVPVGFWQRFIARMLIS-----------LAEMDLQLFENKKNTKSRNRK----------------VTIYSFTGSQRNRCSTFRVRRNQTIYWQEGLLVTFDGG-------YLSVESSDVNWKKKKSGG--IKIICQSEMRDFSAMAFITDHVNSLIDQWFPALT---ATESDGTPLMEQYVPCP--VCEASWAQHADPNER------------------------------------------------------------------------------------------SESVQYFDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLE-NSKLEHTEGENSILGQGGSGTVIYQARYQGQPVAVKRFHIKKFKNSANAPADTMLRHLR-------AMDAMKNFSDFRQEASMLHALQHPCIVSLIGISIHPLCFALELAPLGSLNTVLSENAKDSSFMPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSL-------SAKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIR---PRIVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIRPVLGQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYMLPCGKQSAFFSSQSQEYTVVFWDGKEESRNYTVVNTEKGLLEVQRMTCPGMKLSCQLKVQSSVWIATEDQKIYIYSLKGMCPLSVPQQALDTPAVVTCFLAVPVIKKNSFLVLAGLADGLVAVFPVARGTPKESCSYLCSHTANRSKFCIPDEDARQNPYPVKAMEVVNSGSEVWYSNGPGLLVIDCTILDISRRLEPYAAPSMVTSLVCSSDCRGEEMVWCLDDKANCLVMYHSATYQLCARYFCGDPNPLRDTFSVQPSVLETPGS-HKTTSKGPVEECIADVSIMYSEELGTQILTHQDSLTDYCSMSSYSSSPPHQDPRSPSSLPSSLTSYSSVPFSANYEDSDRLQEPSVTSDRTEHDLSPMDGETFSQHLQAVKVLAVKDLIWVPRHGGDIIVIGLEKDSGAQRGRVIAVLKARELNRHGVLVDAAVVAKDTVVCSFANENTEWCLAVWRGWGAREFDIFYQSYEELGRLEACTRKRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q38SD2-1", "uniprot_id": "LRRK1_HUMAN", "id": "Q38SD2-1", "name": "Leucine-rich repeat serine/threonine-protein kinase 1", "aln": "-----------------------------------------------------MAGMSQRPPSMYWCVGPEESAVCPERAMETLNGAGDTGGKPSTRGGDPAARSRRTEGIRAAYRRGDRGGARDLLEEACDQ-----CASQLEKGQLLSIPAAYGDLEMVRYLLSKRLVELPTEPTDDNPAVVAAYFGHTAVVQELLESLPGPCSPQRLLNWM-LALACQRGHLGVVKLLVLTHGADPESYAVRKNEFPVIVRLP-----------------------------------------------------------------------------------------------------------LYAAIKSGNEDIAIFLLRHGAY------------------------------------------------------------------FCSYILLDSPDPSK-----------------HLLRKYFIEASPLPSSYPGKTALRVKWSHLRLPWVDLDWLID------------------ISCQITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPDP----------------------------------------------WACPLKCCKASRNALECLPDKMAVFWKNHLKDVDFSENALKEVPLGLFQLDALMFLRLQGNQLAALPPQEKWTCRQLKTLDLSRNQLGKNED-------------GLKTKRIAFFTTRGRQR-----------------------SGTEAASVLEFP-------------AFLSESLEVLCLNDNHLDTVPPSVCLLKSLSELYLGNNPGLRELPPELGQLGNLWQLDTEDLTISN---VPAEIQKEGPKAMLSYLRAQLRKAEKCKLMKMIIVGPPRQGKSTLLEILQTGRAPQVVHGEATIRTTK------------------------------------WELQRPAGSRAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKSLEGQEGLRQLIFHVTCSMKDVGSTIGCQRLAGRLIPRSYLSLQEAVLAEQQRRSRDDDVQYLTDRQLEQLVEQTP----DNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIRAEDLRMLLVGTGFTQQTEEQYFQ-FLAKFEIALPVANDSYLLPHLLPS----------------------------------------KPGLDTHGMRHPTANTIQRVFKMSFVPVGFWQRFIARMLIS-----------LAEMDLQLFENKKNTKSRNRK----------------VTIYSFTGNQRNRCSTFRVKRNQTIYWQEGLLVTFDGG-------YLSVESSDVNWKKKKSGG--MKIVCQSEVRDFSAMAFITDHVNSLIDQWFPALT---ATESDGTPLMEQYVPCP--VCETAWAQHTDPSEK------------------------------------------------------------------------------------------SEDVQYFDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLE-NSKLEHSEDEGSVLGQGGSGTVIYRARYQGQPVAVKRFHIKKFKNFANVPADTMLRHLR-------ATDAMKNFSEFRQEASMLHALQHPCIVALIGISIHPLCFALELAPLSSLNTVLSENARDSSFIPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSL-------DVKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIR---PRIVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIAKKLSKGIRPVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYELCCGKQTAFFSSQGQEYTVVFWDGKEESRNYTVVNTEKGLMEVQRMCCPGMKVSCQLQVQRSLWTATEDQKIYIYTLKGMCPLNTPQQALDTPAVVTCFLAVPVIKKNSYLVLAGLADGLVAVFPVVRGTPKDSCSYLCSHTANRSKFSIADEDARQNPYPVKAMEVVNSGSEVWYSNGPGLLVIDCASLEICRRLEPYMAPSMVTSVVCSSEGRGEEVVWCLDDKANSLVMYHSTTYQLCARYFCGVPSPLRDMFPVRPLDTEPPAASHTANPKVPEGDSIADVSIMYSEELGTQILIHQESLTDYCSMSSYSSSPPRQAARSPSSLPSSPASSSSVPFSTDCEDSDMLHTPGAASDRSEHDLTPMDGETFSQHLQAVKILAVRDLIWVPRRGGDVIVIGLEKDSGAQRGRVIAVLKARELTPHGVLVDAAVVAKDTVVCTFENENTEWCLAVWRGWGAREFDIFYQSYEELGRLEACTRKRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KHT3-1", "uniprot_id": "A0A0B4KHT3_DROME", "id": "A0A0B4KHT3-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSDSDEARAQGDIGAMEVGAQKLFSNSHPPQKQLVQPLDHPTPTKRQIKTNATHSPNATFLNKCNSCRASWAPTCAVRHKTAWINDHKNVAIDFPQFNAREEVRQIKHGELRTAVISGDERTVRVLLAALGTERQIIVNMAPSGANTLLFLACQSGYESITQRLLDAGADGRSHAVTKYSPLYAAVHSGHLGIARLMLDHFPELIQQPTVERWLPLHAACINGHIKLLELLISYSYPDYLYQTYRDEEGQWEWRLPFDANAHDVTGQTSLYIASILGNKQLVGVLLKWQLHCRRTLGDSASSVSTPITPTRKRISFGIQAIMSKLHISGESEGPDDLASQESTECQRCPINVNLLCGAARETALLAAVRGGHLDVVQSLLQHGANPNIVAKPVEDHNDPKCCEEIYGLSNVPIAEACKQRSLAMLDLLLKHGARDDNGTAIGMAITCGDEAILSRLLARRVHPDSDYKINKKGLPTPVEVNVFLPSTSNISYSAMFPNNPTIIDWHSMGSSVQLSVVRVPWMVSGVLLLNPKLQSHPRLNEVALTAITRIDFSHNVLTSIPQEL-FHLVSLRYLNVAQNKITDLPAPIG-QTYGCPVLDELFLQDNQLTTLPAAIFHLPALSILDVSNNKLQQLP-----FDLWRAPKLRELNVAFNLLRDLPVPPMQTSSSLLSLDKLN--LQSFEEPPSNKPRNVTQQRLTHRNLWSATLDITDNDMKWQHEQDLGDGKTAGVGSSQLSSLNIANNLFTSIPAALPCLAVN-LTRLNMSYNSLRSMGHVTSYPATLKQLDLSHNEISCWPSLPRITESDPHLLCYSCVQLPEGRDDDYKTASSKGSSSSATSFRASVLKSVCRHRRHLRLEALRTLILADNLLTRIQLSTDDATTLFNESEDADWSVVGVNRSKVIFPNLSMLDMTNNCLKEIPASLHELSSLSVLNISGNVNITELPPHLGLLSRLWNLNTRGCLLQEPLRSMIESKKHKTMDIVGYLKSIYEDAQPYARMKLMVVGVAGIGKSTLLDLLRQGAGSGSSSSSHRSRASENHWAKRMGHARSTSRSHRHSSASSANISTVGVDIGTWICEKRKRAPGSHGPVVFRTWDFGGQKEYYATHQYFLSKRSLYLVLWRISDGHKGLAELLQWLGNIQARAPNSPVIIVGTHFDAVGESISPQKAEQLQQLIREKFIAIPDAEKIGLPRVIDS--IEISCRTLHNIHLLANIIYDTAMQLRSPGSKE---PMLLQKIPASYIALEDIVNVIACNLRAAGRDPVLDGEQYKRLVTEQMRLHNYKSFRDAAELQQATTWCHENGVLLHYDDAT--LRDYYFLDPQWLCDMLAHVVTVREINPFAPTGVMKLDDLQMLFRSVQVQGNGNRSYIVSLLNKFEVALTWDSRTLLIPSLLPSQEAATPNSGSTVKLSQRSRGRSLGCSVSQEVNLNNLIYEQRSAPSSSSSSASVSQGLRRILLMTYFPSGFWSRLITRILADEQIIEAIRGVYMASQDYADFDLRTSLEQDTQWNLWQTGLALYYGPILIFKIWEVPFQKTERTQPFRTDGNRFKLKQDGIWSDVNLSSSSILEVYFPLYEVNISQEVDDNERQLLAEIRPHMSQVAKLLALTVDHIDLLLEDWYPSLGTRFVHTSEGRFLITRLVLCPRCLWKLQLQQNNEPSDREVPPVGCNRPSRSSRRGAGAYFLHGVGDPGEDGALNVFSAYLNATARRERRSEDSLGAGSDADSGVGPDSAGSSRNTSVDGHPGYHLPDNSNVCYAWMIEECILSVYNQSKISCPVH--LEQSMAQLAPDVIFADIPDKHTIPSECIIKGSLLGRGAFGFVFKANCKVRGARSFKPVAMKMLQPVPPGARAKESALMAFKVAVGKWDRDPLQHSCKAYCTARQELAVLLTLKHPNIVPLVGICIKPLALVLELAPLGGLDALLRHYRRSG--AHMGPHTFQTLVLQAARAIEYLHRRRIIYRDLKSENVLVWELPQPHTEDSPRNLVHIKIADYGISRQTAPSGAKGFGGTEGFMAPEIIRYNGEEEYTEKVDCFSFGMFIYENISLRQPFEGHES--IKECILEGSRPALTQRETQFPTCCLDLMVLCWHEQPRRRPTASQIVSILSAPECIHLLDVVAMPHSEKIVCG---VFQSLVGMGDDERCGLELWLPSFGSRIDILDCSP---SGSLLQCNSISCSPQPQVAPPKTPENGANSRARSAQRLPKMNMLCCCLVGEAIWMG-------------DVSGNLHAYSTSTYAHLFSYMLDPN-----IKSAVISLVYMEKIARVAVG-----THNGRVFLVDATQMPSN---CAFAEGSFVLTEICSG---------------FVLHAACSVVVDGIYELWCGEIAGKINVFPLN----ENGVSGHQALCHSEEPNLIEDVKVARMCSNESHVFS---CLYPGCMVYQWDVISKRIENKLDCSKLLPCSESLQSIAIDEHVNLIKCQISALAAHNSELYIGTTWGCLIVAELHTLRPIS----VFRPYENEIKSIITLSKDNVP----LIATIGRRYRSLISRYVDSAESSTKSSAVSTPTHG--------AAKSVPPADVDNHIHCLLWRAKHWT----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . .. .: :::* : .* ** : : . ** :.. * . .: ** . *. .* .*.: ** :.: :*: :. : .*: * ** .**: :::**: .* : *.:* *** * **::.*: *:. **:*** : * :* .*.. .* . *. *.: .. * * ::*. * : *::. **.:*:* * *.::*. : : *:.*: **:::*:: :** . : *. * *: :..*:*: **..::**. *. * .*:* *::* : **.**::: * * :**. ::: .** .*: . *: * :* :. *.. : :.* : .:* :. : . * ::* *:*: : :* * *. * : . * : * : : * * ** :..* . .: * :.:.: *:* * ::::::: . .: .*.:* :.:* *. :*.*: *..** * :..* .: ****.** *..**:*: .. : : * :*. . :.:*:: ..*: **:::** . ******::*: * .. .. *::: * :: : .. .* *..**:** . :.:* *::.::**:*:*.:: *.:.:*:* ** **:*:***: *::****:* : .: :: *: : : ..:. *:* : . ****:.*.. . * ::*:..: .::. **. : : ** **::*:: * . . . * ..* .:** : :.::* :**.* :: *.*.***: *:: **: ***** **.: * ::..:: ...* .**:: :**:**: .. . : :..*: :* ***:**. . : *:* **** :.. .: . . :: ::*:: *::.* ***.*:*:*:* . :*. * *: :.. :. .: ..*:... .: :* ..**. *: *:*: .: . *:.: . ::. : ... : : : . :*: .**:: *:::*:*:* . *:* *: : * ** : : *: :*.:: *: : :*:*:*:. : . **** * * .: :*.*:::::*:* : : :. :: : . :* ... :. . :***:* :: *: .* :: .: * :. *** ::* :*:** **.*:**.*:**.:.******..*:::* . :.. :* *.:. * * .: ***::.**: ****:*:***.* . :: ::**::*******: .** *. ** *: **** . * **** **:**.:** :* ::* **.. * : : :* **.* * * **: **. :*.:** * .:** :. * :: : :. :... : :. *.:* . : .. * .* .. *: : . : . :* . . * * . :: * *. .* . * :. ...: ::* *: : . :.: . :. : * * ::. ::::*.: : .: *.* : :**. * *.. : . :** : *.:. * * : : : * **.: . ::: .* * : .:. . : : * . :. . : : : .. :...:* : . * : .*:::: :: :: * .. :* *.**. . :**.: * . . **:* :..: . ... . .. *: : : * * : . ", "identical_positions": 447, "similar_positions": 697, "identity": "17.13%" }, { "cls_id": "homologset.agr.MGI:2142246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99KD5-1", "uniprot_id": "UN45A_MOUSE", "id": "Q99KD5-1", "name": "Protein unc-45 homolog A", "aln": "MTVSGPETPEPRPSDPGASSAEQLRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAILHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTE-ETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVIFDALKEGVKKGFRGKEGAIIVDPARELKVLINSLLELLTEVGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGGSLQDAAGE--LTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRNWFEGHGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEREEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERS-VLFAVGSALVNCTNSYDYEEPDPK-MVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVV-SAMTCMVKTESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQ---TKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSG-------------LQNFEALMALTNLAGISERLRQKILKEKA-----VPMIEGYMFEEHEMIRRAATECMCN-----LAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLRRAAAGGLAMLTSMRPALCSRIPQVTTHWLEILQALLLSPN-QELQHRGTVVVLNMMQSSKEIAGTLMESEVLEILS---VLAKGEESPVTRAAAACLEKAVEYRLIQPNQDGE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32PZ3-1", "uniprot_id": "UN45A_RAT", "id": "Q32PZ3-1", "name": "Protein unc-45 homolog A", "aln": "MTVSGPGTPEPRPSDPGASSAEELRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAILHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTG-ETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLELLTEIGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGGSVPEAAGE--LTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVALLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERS-VLFAVGSALVNCTNSYDYEEPDPK-MVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVV-SAMTCMVKTESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQ---TKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSG-------------LQNFEALMALTNLAGISERLRQKILKEKA-----VPMIEGYMFEEHEMIRRAATECMCN-----LAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLRRAAAGGLAMLTSMRPSLCSRIPQVTTHWLEILQALLLSPN-PELQHRGTVVVLNMMESSKEIASTLMESEVLEILS---VLAKGEESPVTRAAAACLEKAVEYRLIQPNQDGE-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3U1-1", "uniprot_id": "UN45A_HUMAN", "id": "Q9H3U1-1", "name": "Protein unc-45 homolog A", "aln": "MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMG-ETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQAVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSLQDPPGE--LAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKCSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRLEERS-VLFAVASALVNCTNSYDYEEPDPK-MVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVV-SAMVCMVKTESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQ---TKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSG-------------LQNFEALMALTNLAGISERLRQKILKEKA-----VPMIEGYMFEEHEMIRRAATECMCN-----LAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSN-QELQHRGAVVVLNMVEASREIASTLMESEMMEILS---VLAKGDHSPVTRAAAACLDKAVEYGLIQPNQDGE-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHW4-1", "uniprot_id": "Q9VHW4_DROME", "id": "Q9VHW4-1", "name": "", "aln": "MTNT--------INSEEVSDAGSYKDKGNEAFKASRWEEAVEHYGKAIKAGSKHKELAVFYKNRAAAYLKLGKYENAVEDCTESLKAAPGDPKALFRRAQAYEALEKFEEAYKDATALFKADPGNKTVQPMLQRLHVVVEERSARNAKTSTKVKQMMDLTFDLATP-IDKRRAAANNLVVLAKEQTGAELLYKDHCIAKVASLTKVEKDQDIYVNMVHLVAALCENSVERTKGVLTELGVPWFMRVLDQKHENCVSTAQFCLQTILNALSGLKNKPDSKPEKELCTRNNREIDTLLTCLVYSITDRTISGAARDGVIELITRNVHYTALEWAER----LVEIRGLCRLLDVCSELEDYKYESAMDITGSSSTIASVCLARIYENMYYDEAKARFTDQIDEYIKDKLLAPDMESKVRVTVAITALLNGPLDVGNQVVAREGILQMILAMATTDDELQQRVSCECLIAASSKKDKAKALCEQGVDILKRLYH-SKNDGIRVRALVGLCKLGSYGGQDAAIRPFGDGAALKLAEACRRFLIKPGKDKDIRRWAADGLAYLTLDAECKEKLIEDKASIHALMDLARGGNQS-CLYGVVTTFVNLCNAYEKQEMLPE-MIELAKFAKQHIPEEHELDDVDFINKRITVLANEGIT-TALCALAKTES----HNSQELIARVLNAVCGLKELRGKVVQEGGVKALLRMALEGTEKGK---RHATQALARIGITINPEVSFSGQRSLDVIRPLLNLLQQDCTA-------------LENFESLMALTNLASMNESVRQRIIKEQG-----VSKIEYYLMEDHLYLTRAAAQCLCN-----LVMSEDVIKMFEGN-NDRVKFLALLCEDEDEETATACAGALAIITSVSVKCCEKILAIAS-WLDILHTLIANPS-PAVQHRGIVIILNMINAGEEIAKKLFETDIMELLSGLGQLPDDTRAKAREVATQCLAAAERYRIIERSDNAEIPDVFAENSKISEIIDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51534-1", "uniprot_id": "SHE4_YEAST", "id": "P51534-1", "name": "SWI5-dependent HO expression protein 4", "aln": "---------------------MPLCEKGNDPIDSSTIDSLCAAFDKTLKS-------------------------------TPDVQKYNDAINTIFQLRQKSESGK------------MPADLTNSEALKDRQKIEEILTRSYQDHSESRVHLSKLIQNDIPFALNLFEILSRSSIHVFVG------------------------------------------CFSNKDATIALLNELQIR--------IHYGEDTHVTYLLSIILQLLNKFKYN-------------FKEVRFLVKELILRISEDEVKS-----MMLIIFAELQS--------------------------------------SFQKDFDKAVVDFMSSLIVEAEIDVGNDPLSIIVKTLSELYPSLTTLCSEIFLTKGLSKLFKKRVFEEQDLQFTKELLRLLSSACIDET--MRTYITENYLQLLERSLNVEDVQIYSALVLVKTWSFTKLTCINLKQLSEIFINAISRRIMPKIENVNES-AVKLEEVPKVEMS------------VEALAYLSLKASVKIMIRSNESFTEILLTMIKSQKMTHCLYGLLVIMANLSTLPEESNGSSQSINDLKNYADLKGPGADKVGAEKESKEDILLFNEKYILRTELISFLKREMHNLSPNCKQQVVRVIYNITRSKNFIPQCISQGGTTIILEYLANKQDIGEPIRILGCRALTRMLIFTNPGLIFKKYSALNAIPFLFELLPRSTPVDDNPLHNDEQIKLTDNYEALLALTNLASSETSDGEEVCKHIVSTKVYWSTIENLMLDENVPLQRSTLELISNMMSHPLTIAAKFFNLENPQSLRNFNILVKLLQLSDVESQRAVAAIFANIATTIPLIAKELLTKKELIENAIQVFADQIDDIELRQRLLMLFFGLFEVIPDNG----TNEVYPLLQENQKLKDALNMSLKRGDSGPEFSAAIPVILAKIKV-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**: :... : ::: : :: . ::::: * * . : *. :.: : . :.: .::.:::: : : :: ::.* * . . * . *. * . . *. ::: *. : :*: *:. *: ::: :.. : :: : . . . :: : : * . : . . : .:: :: *:: : . ::. : : . : : * : : ... : .. :* : :: *.:: * : . :. . :. ::** : : : .:.****::.*. * : .: : . *: : : : : *:.: :.* . : .: .: : :* ::*. : * . . . . : : : : : .: * * ..:: : **: : : : :** :: : : *: . :**::: * ** : * :.: *..** . . :*:*:*:******. . :.: *. . ** ::::: : *:: : :.* *.:: .. .: : : ..::*. .* * *. :* ::: ...: : ::.: . . :::* ::.:.:.: : . .:: :*. * . . . : * :: . ", "identical_positions": 75, "similar_positions": 280, "identity": "7.52%" }, { "cls_id": "homologset.agr.MGI:2142282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q571B6-1", "uniprot_id": "WHAMM_MOUSE", "id": "Q571B6-1", "name": "WASP homolog-associated protein with actin, membranes and microtubules", "aln": "MDSEQPDSLDGWVPLREDLFPEPERHQLRFLVAWNAAKGQFAVTCHDRTAQRRRR-----------ERREAGDGGCSWAGVLSPAGFRGAHRQLAALWPALEPCFPPLPPELDAASGAGWGLGRGLWALLWPLLWPAPADPGDSALQELCRQLEHYLGLAAEGCGGATVRDVLFPAPGDSADCEGLSEFRERTLRARLGQTATRLHQVLQDHGKANTMVALMKVYQEEDELYQELVTMATTFFQYLLQPFRDMREVATSCKLGILKSLDEDELGPRRVAALQKEASEWTRQAEEAVGSIQDITVNYFKETVTALTGMQKQMEQDQKRFGQAAWATAMPRLENLKLMLARETLQLMRAKELCLKHRQAEIQRKVEDLPRQGKQLDVVDELEIQCYEIQLELYDVKLEMLRNEETILVTRLDSVKRLITEKQAEVIYYDPCESPEELQSLAPDLELHLGDNRELRALSQQCQRLEAQRGRICSRRALLRNRKDHCRENHQLRLQQAKQSLRHLHQHHSIQMKRDKVKEEEQKKKEWIDHERQKTLERLRAYKEKCPAHRSALKTTCSESMVSNLPGGRSQKRLSTAHHHKTAHPASSKTGSAVPLPEAS-VRPPEHQDPCGSVPVQAFVPVSDQTLSGSSEDLSLPPQPPAPPLPPPPPPPPPPPLPPALSSFQGTTHQNLGLRTLATEDRPLPLACDPSAGRPCD----YQGPGSMDEVLASLRQGKASLRKVETPTLPHPGTSVNEQVLAAIRQGVQLKKVHTGQGVDPGKKSTS-----DLERSIREALERIKKVSADSEEDNDEPSPTEWDR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZKN4-1", "uniprot_id": "D3ZKN4_RAT", "id": "D3ZKN4-1", "name": "", "aln": "MDSEQPDSLEGWVPLREDLFPEPERHQLRFLVAWNAAEGQFAVTCHDRTAQRRRR-----------GRQEAGDGGCSWAGALSAAGFRGAHRQLAALWPALERCFPPLPPELDAASGAGWGLGRGLWALVWALVWPAPANPGDAALQDLCRQLEHYLGLAADGCGGATVRDVLFPAPGDSADCEGLSEFRERMLRARLDQTVARLRQLLQDHRKANTMVTLMKVYQEEDEVYQELVTMATTFFQYLLQPFRDMREVATSCKLGILKSLEEDELGPKRVAALQKEASEWTRRAEEAVVSIQDITVNYFKETVTALTGMQKQMEQDQRRFGQAAWATAMPRLENLKLMLARETLQLMRAKELCLKHRQAEIQRKVEDLPDQGKNVGVVDELEIQYYETQLELYDVKLEILRNEETILVTRLDSVKRLIAEKQAEVVYYDPCESPEELKSLAPDLELHLGDNRELRALSQQCQQLEAQRGRICSRRAQLRNRKDHCRENHQLRLQQAKQNVRHFHHHHSIQMKRDKIKEEEQKKKEWIDHERQKTLERLRAYREKGPAPRSALKTSCSESMLSNLSGGCSQKRLSTAQHKTAAHPASSKTRSASPLPEAT-VKPPEHQDPCGSAPGLALAPVSDQTLSGSSEEMSLAPPPPPP--PPPPLPPPPLLPPSALPSFQGTTHQNIGFQTLATEDQPFPLACDMSARR----------PGGSDCQEGFQRPG--------------------------------------------------------------------QDLSPESRNDHPAPSPHLGQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TF30-1", "uniprot_id": "WHAMM_HUMAN", "id": "Q8TF30-1", "name": "WASP homolog-associated protein with actin, membranes and microtubules", "aln": "MEDEQPDSLEGWVPVREGLFAEPERHRLRFLVAWNGAEGKFAVTCHDRTAQQRRLREGARLGPEPEPKPEAAVSPSSWAGLLSAAGLRGAHRQLAALWPPLERCFPRLPPELDVGGGGAWGLGLGLWALLW----PTRAGPGEAALQELCGQLERYLGAAADGCGGATVRDALFPAEGGAADCESPREFRERALRARWVEADARLRQVIQGHGKANTMVALMNVYQEEDEAYQELVTVATMFFQYLLQPFRAMREVATLCKLDILKSLDEDDLGPRRVVALEKEAEEWTRRAEEAVVSIQDITVNYFKETVKALAGMQKEMEQDAKRFGQAAWATAIPRLEKLQLMLARETLQLMRAKELCLNHKRAEIQGKMEDLPEQEKNTNVVDELEIQFYEIQLELYEVKFEILKNEEILLTTQLDSLKRLIKEKQDEVVYYDPCENPEELKVIDCVVGLQDDKNLEVKELRRQCQQLESKRGRICAKRASLRSRKDQCKENHRFRLQQAEESIRYSRQHHSIQMKRDKIKEEEQKKKEWINQERQKTLQRLRSFKDK-RLAQSVRNTSGSEPVAPNLPSDLSQQMCLPASHAVSVIHPSSRKTRGVPLSEAGNVKSPKCQNCHGNIPVQVFVPVGDQTHSKSSEELSLPPPPPPPPPPPPPPPPPPPPLRALSSSSQAATHQNLGFRAPVKDDQPRPLVCESPAERPRDSLESFSCPGSMDEVLASLRHGRAPLRKVEVPAVRPPHASINEHILAAIRQGVKLKKVHPDLGPNPSSKPTSNRRTSDLERSIKAALQRIKRVSADSEEDSDEQDPGQWDG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.******:****:**.**.*****:********.*:*:***********:** : **. . .**** **.**:************.** *** ******...*..**** *****:* *: *.**::***:** ***:*** **:*********.**** *.:****. ***** **** :: :**:*::*.* ******:**:******* ******:** ********** ****** ***.*****:**:***:**.**:***.****:***** **************.**:****:**** :**********:****:*:******************:*::**** *:**** * *: .******** ** *****:**:*:*:*** :*.*:***:**** *** **:******.****: : : *: ..* *:: * :***:**::*****::** **.***:*:***::*****::.:*: ::**********:***********::******:***::::* :*. :*: **.: .**... **: .* * :. .**:. . **.** *:.*: *: *. * .:.**.*** * ***::**.* **.* **** **** . .* *.:****:*::: ..:*:* **.*: .* * **. * . * * : :*.:*.:* .* : ", "identical_positions": 448, "similar_positions": 167, "identity": "55.04%" }, { "cls_id": "homologset.agr.MGI:2142292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V810-1", "uniprot_id": "G3V810_RAT", "id": "G3V810-1", "name": "Myotubularin-related protein 10", "aln": "---------------MVAALWTPRRAYLSSSCEFLKAAWAVTDDKISSEP----------KIKKLEPVLLPGEIVVN------------------------EVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDP-------MPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNP--------------------TELIIYCKDFRIVRFRFDE------SGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSA-NKVNGVSSG----GGGVWSGAGSPSSQRTPLFETYSDWDRETKRTGASGWRVCSINEGYMIS-------TCLPEYFVVPSSLADQDLKIFSPSFVGRRMPCWCWSHSNGSALVRMALIKDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTLPNIQEIQAAFVKLKQLCVNEP---FEETEEKWLSSLESTRWLEYVRAFLKHSAELVYILESQRLSVVLQEEEGRDLSCLVASLVQVMMDPYFRTITGFQSLVQKEWVMAGYPFLDRCNHLK-----------RSEKESPLFLLFLDTTWQLLEQYPAAFEFSETYLAVLCDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPYYIGKSTPCIQNGSRKSF--KRTKKSYSSTLRGMPSCLKNGLISDQELLPRRNSLILKLKPDPPQHGDSQHSGAEQYFKEWFSRPANLHGIILPRLSGTHIKLWKLCYFRWVPEAQINLGGSIMAFHKLSVLADEVDKLSRMLRQHHSGPLEACYAELDQSRMYFRATGPH--DTLGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPM9-1", "uniprot_id": "MTMRA_MOUSE", "id": "Q7TPM9-1", "name": "Myotubularin-related protein 10", "aln": "----------------MFSLKPPRPSFRS----YLLPP-AQTDDKISSEP----------KIKKLEPVLLPGEIVVN------------------------EVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDP-------MPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNP--------------------TELIIYCKDFRIVRFRFDE------SGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSA-NKVNGVSSG----GGGVWSGAGSTGSQRTPLFETYSDWDRETKRTGASGWRVCSINEGYMIS-------TCLPEYFVVPSSLADQDLKIFSHSFVGRRMPFWCWSHSNGSALVRMALIKDALQQRKIDQRICNAITKSHPQRSDVYKSDLDKALPNIQEIQAAFVKLKQLCVNEP---FEETEEKWLSSLESTRWLEYVRAFLKHSAELVYILESQRLSVVLQEEEGRDLSCLVASLIQVMMDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLK-----------RSEKESPLFLLFLDTTWQLLEQYPAAFEFSETYLAVLCDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDWALQFTAKDRTLFHNPFYIGKSTPCVQNGSRKSF--KRTKKSYSSTLRGMPSCLKNGIITDQDLLPRRNSLVLKLKPDPPQHTDSQHSGAEQYFKEWFSRPANLHGIILPRLSGTHIKLWKLCYFRWVPEAQINLGGSIMAFHKLSLLADEVDMLSRMLRQHRSGPLEACYAELDQSRMYFRATGPH--DTLGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXD2-1", "uniprot_id": "MTMRA_HUMAN", "id": "Q9NXD2-1", "name": "Myotubularin-related protein 10", "aln": "----------------MFSLKPPKPTFRS----YLLPP-PQTDDKINSEP----------KIKKLEPVLLPGEIVVN------------------------EVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDP-------MPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNP--------------------TELIIYCKDFRIVRFRFDE------SGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSA-NKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWRVCSINEGYMIS-------TCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMALIKDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTLPNIQEVQAAFVKLKQLCVNEP---FEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLK-----------RSEKESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKSTPCIQNGSVKSF--KRTKKSYSSTLRGMPSALKNGIISDQELLPRRNSLILKPKPDPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLCYFRWVPEAQISLGGSITAFHKLSLLADEVDVLSRMLRQQRSGPLEACYGELGQSRMYFNASGPHHTDTSGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JMF6-1", "uniprot_id": "MTMRA_DANRE", "id": "A0JMF6-1", "name": "Myotubularin-related protein 10", "aln": "----------------MFSGKQTKPTFKS-----YLPP-LQTDLKKSPQL----------PIKKLEAKLLPGEIVVN------------------------EANFVRKCIGADSGQDDLWGKLVCTNFKVSFISHNS-------LPQQRFQCTHRLLGEHDIPLACVEQVVTVNDVKGKQKILGSNQKLKFNP--------------------TELILYCKDFRIIRFRFDE------AGPESAKKVCLAIAHYSHPADPQLLFGFEYVGKRYHGSAGERVNGVDPG---------------GGLQTPLFDCSSDWDREIKRTGASEWRVCTINQGYFIS-------PSLPEFFVVPVSLADQDLKQYACCFYSQRIPLWCWNHPSGSALVRMSNISDPQQQRKVEQRISSAITKSHPLRSDVFKSDLDKNLPNIQDIQAALLKLRQICVIES---FEESEEKWLSSLESSRWMEYVRTFLRHAVEVVYMLESRHVSVILLEKEDRDLSCVISSLVQLMCDPHCRSLHGFQALIQKEWVMAGHRFLDRCNHLK-----------KSDKE------------ELWNQYPAAFEFTEVYLTVLGDSMWVPVFSTFLFNCPRQRAEHSRDFASSKSIHLGQDQALRFPPVWDWSQQFSLKDQTLFNNPLYVGKIATCLQNGTVKTFTHRRSKKNYSSTVRGLPSLMRNGSLGPNDTLTRRNSLVLRLRSDLSQVREQPETPSERFVRDFFSRAVDLQGLLLPQLLPSHLSVWKLYFLRWVPEAQIPHGGPVTAFHKLSVLTDEIEMLQNQLRQYKGAAGTANTSHAEHSKMYFKATSTP-QQCPAPPGYLSSSFPFSPVGNLCRPGILGTPLSKFLNGAKIWLSTETLANETI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY15-1", "uniprot_id": "Q9VY15_DROME", "id": "Q9VY15-1", "name": "Myotubularin phosphatase domain-containing protein", "aln": "MATGGGGSGHGGAGSAGNADHHKRNTFTS-----YVAP-LPGDLRATADTNEWCLPSDLRDVHLAKPRLLHGEQIVASAPAYMYSPIDPMDSSGGSGSTLSAISSASGTPADRHHKEATFGLLSVTNFKLAFVPLHEKRNQAITAPLIDLYQENTYLGRNEITLNNIDHIYTITELGRAASALQAARGMASHAGMSRRKKLEPFKQQNISGRIAALHIVCKNFRLLKFAFQQQDSKMFGASDQGKLIASALVRFAYPMRHDLSFAYAHREPYYSTLG---ASG-----------------------TSMYATKNDWARELIRCGATEWQVVSCASVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCDSRAAFWVYSYGSSAALVRLAELQPAAQQDTKSENVMLELVRKCDAGRQLKLLQLTDRLPSIQDVLRAYQKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASATLRSG-VTCVLQESNGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQRLKAVTDSQ------------LVLRPVWDWGEQFSDKDKMFFSNPLYQRQRGDLGAQAAAVAH--RRSLAVGSKGAHGAASGVTPSRNTINPQLFATASSVPQDRYLQPAHRIFDLQVWDQCYYRWLP-ILDIRGGGQPQVDLYHRLLLSNIAKVQRCLDYQNFDDLPDAYYEFAGESRPNQHKDEKPDKEDEAEFVDGVERRRKPTAKAATPTSG-LTSVTGNLQLSTLSSFFPFGNPIAGDAPLQLYDILSSSSELLMETSSFLDKSSIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: * .. * : ..: :: :. ** ** :* . . . : :* * :***::*:. . * : : **.:::.* :::: *:.: . * . : : :. : * : **:**:::* *:: ...:..* :. *:.::: * :* *.: : * . .* *.:: .** ** * **: *:* : . ::. :* .:*:* * : : : : .* . * . * :.: ..:****:: :. ** . .:.: :.:. :: :* . **.**:: * **:::*. *. * ::*:*. **.:.*: ** *::: * *.* :: :* *.:.***.* ::** *:: **: *:: ***:*:***** : * * .*: ..:: :* :*:* ***::.**:.* ** :.:*.** *: ** : : * : .****. **: **: :* ** * : :.: :. :*: *. :* .* : . : * * : : : . :: ::. :::* *:: * : . .. *::::: : : .. : . . :. :. . **: .* *.** . . : ..::: :.*.:: :: ", "identical_positions": 149, "similar_positions": 249, "identity": "16.7%" }, { "cls_id": "homologset.agr.MGI:2142330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP99-1", "uniprot_id": "D3ZP99_RAT", "id": "D3ZP99-1", "name": "", "aln": "---------MAAFAHLLKRLGWAA-----RAQEVTEQELEEECS--VPGAPWRLLVAPRCWQRLHGGAAAASGLRFGASAVQGWRARMEDAHCAQLALPGLPSG--WAFFAVLDGHGGARAARFGARHLPGHVLGELGPAPREP-DGVRQALRSAFLHADSQLSKLWPRC--DPGGSTAVALLVSP--RFLYLAHCGDSRALLSRSGSVAFCTEDHRPHRPRERERIHDAGGTVRRRRVEGSLAVSRALGDFAYKQAPGRPPELQLVSAEPEVAALAR-QDEDEFVLLASDGVWDALSGADLAGLVTSRLRLG-LDPELLCAQLLDTCLCKGS------LDNMTCMVVCFPG------------------------------------------------APRPCEEAISK----------------EMALDAVLSHKVAGEQVKWPVGGMVGQCGLSAHLLLRAVCLCSGTSMPKHGFQDPG--LRGHPGLASWRRATQQGHCHS-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGL1-1", "uniprot_id": "PPM1N_MOUSE", "id": "Q8BGL1-1", "name": "Probable protein phosphatase 1N", "aln": "---------MAAFVRLLERLGWAA-----RAQQVVEQEVEEECS--VPGASGSLLAAPRCWQRLHRGAAATSGLRFGASAVQGWRARMEDAHCARLALPGLPSG--WAFFAVLDGHGGARAARFGARHLPGYVLGELGPAPQEP-DGVRQALRSAFLQADAQLSALWPRG--DPGGSTAVALLVSP--RFLYLAHCGDSRALLSRSGSVAFCTEDHRPHRPRERERIHDAGGTVRRRRVEGSLAVSRALGDFAYKQAPGRPPELQLVSAEPEVAALAR-QDEDEFVLLASDGVWDALSGADLAGLVTSRLRLG-LDLELLCAQLLDTCLCKGS------LDNMTCMVVCFPG------------------------------------------------APRPCEEAISK----------------EMALDEALSHKVAELYAS-------AQEPPGLNTVFRTLASEDIPGLPPGGGLHS---KAAVIAEAYSKLHQTPGECQEEEW--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N819-1", "uniprot_id": "PPM1N_HUMAN", "id": "Q8N819-1", "name": "Probable protein phosphatase 1N", "aln": "---------MAVLARQLQRLLWTACKKKEREKEGREEEEEEEAGRRAPEGPRSLLTAPRRAQRPHGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPG--WALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEP-EGVREALRRAFLSADERLRSLWPRV--ETGGCTAVVLLVSP--RFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAALAR-QAEDEFMLLASDGVWDTVSGAALAGLVASRLRLG-LAPELLCAQLLDTCLCKGS------LDNMTCILVCFPG------------------------------------------------APRPSEEAIRR----------------ELALDAALGCRIAELCAS-------AQKPPSLNTVFRTLASEDIPDLPPGGGLDC---KATVIAEVYSQICQVSEECGEKGQDGAGKSNPTHLGSALDMEA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBF9-1", "uniprot_id": "Q9VBF9_DROME", "id": "Q9VBF9-1", "name": "", "aln": "--------------------------------MGHKMGG---------------FLEKPETEKQAQEGHG-NGLRYCVSSMQGWRLEMEDSHSAACRLKDPFAT--WSYFAVFDGHAGSQISLHCAEHLMSTILESESFSKHK----YEAGIREGFLQLDEDMRKLYHDQ---QGGSTAICVFVSP--DKIYLVNCGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIKRINGTLAVSRAFGDYDFKNDGSKSPVDQMVSPEPDIIVCNR-SEHDEFIVVACDGIWDVMTSSEVCEFIRSRLLVT-YDLPMIVNSVLDICLHKGS------RDNMTLLLLLLPG------------------------------------------------APKVDMDAVKA----------------ERSLDQTIVQITKEVIEKHEI----HDFET-LIRLMKRMAIN-IPNLPPGGGLYA---KYYIIEQAFHEKFPDT-PAEIYDYFSM-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8N1Z489-1", "uniprot_id": "A0A8N1Z489_DANRE", "id": "A0A8N1Z489-1", "name": "Protein phosphatase 1B", "aln": "MRTARRASTMEVPSFLRQLVKETEKMVTFFFKGGRRDSGSDDDYYENDPDACSPYLERPILAKDSAEGESKWGITYAMASMQGWRAQMEDSHTCMPEMSDALPD--WSYFAVYDGHAGRTVAQYSSRHLLDFILDTGCVTVEEDVEQVKDGIREGFLAIDRHMHTLSRNESWDHSGSTAASVMISP--RNFYFINCGDSRTFLCRDGHVVFYTEDHKPCNPREKERIQNAGGSVTLQRINGSLAVSRALGDFDFKEVEWRAQTEQLVSPEPEVYELER-SPEDEFLVVACDGVWDAIGNEDLCAFVRNRLHVC-DDLREICSQVIDLCLYKGS------LDNMTIIIICFDG------------------------------------------------APKVTQEALQQ----------------EAELEQLIEQKVAEIIHVIRS----KDEEPDLLYVMKFLASEPIPGLPPGGGVSC---KRDCIIAAYQKYAAAFRPLEPMDTGGSDDST-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P34221-1", "uniprot_id": "PP2C3_YEAST", "id": "P34221-1", "name": "Protein phosphatase 2C homolog 3", "aln": "---------------------------------------------------MGQILSNPIIDKEH-HSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGM----LEQCLIDTFLATDVELLKD-EKLKDDHSGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIVALLKENESESQWFERMRSKNYNIQT-SFVQRRKSIFDFHDFSD-DDNEVFAITTKKLQDRLNR----------SKDNDD-MEIDDLDTELGSS-ATPSKLSGEDRTGPIDLFSLEALLEAGIQIRQRPSSDSDGN--TSYFHGASLSDMLASLSNAAAGETEPNDADDNDDNDGEENGKNENAKKGSKIEEIE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39966-1", "uniprot_id": "PP2C2_YEAST", "id": "P39966-1", "name": "Protein phosphatase 2C homolog 2", "aln": "---------------------------------------------------MGQILSNPVIDKES-HSGADSLTAFGLCAMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEGN----LPRALIDTFINTDVKLLQD-PVMKEDHSGCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLREG-KTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVVALLKEGEDVAQWSDRMKSKAHRTSVRSFADKRRRVFSYYDFSKCNDEQVFAITTKKPQDKFTRDHEAAVASVTAADNDDPMDIDDTDADTDAENLDPSSQSKSKTSGPIDLASLEALLGATGGVK----TDSNGNKVTYTLPQSALAQLLQTMGHDPASSHP-----ENDSNTDHKAGR-------SHLQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .: **** ***:* : : :.: ***.* : . . :: : : *: * : .*.** :::* : :.****:.:. * : **:* *:.** *.* : *::*.**:***:**: :*. *:*: *:: .***:::*.**:** : . :: : : ::* * : ***: :: : :.: : . :: : : ", "identical_positions": 57, "similar_positions": 79, "identity": "10.54%" }, { "cls_id": "homologset.agr.MGI:2142346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AK86-1", "uniprot_id": "A0A8I6AK86_RAT", "id": "A0A8I6AK86-1", "name": "Striatin-4", "aln": "MMEERAAAAVASAAS-CRPLGSGTAPNPTAAAPASSPAPGPGPVGKGG---GGGGSPGPTAGPEPLSLPGILHFIQHEWARFEAEKARWEAERAELQAQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKK-ADLSEQVSNGPVESVTLDNSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGR-SLELNGAGEPVEGAPRASPGPGGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLEQIPFLQNCEDEDSDEDDE-----------LDSVQHKKQRVRLPSKALVPEME--DEDEEDDSEDAINEFDFLGSGEDGEGSPDPRRCASEGNPHELESRRVKLQGILADLRDVDGLPPKVTVPPPGTPQPRPHEG-SFGFSSDVFIMDTIGGGEVSLGDLADLTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSCVLEGHGDAVWGLAFSPTSQRLASCSADGTIRIWDPSSSGSSCLCTFPMAGEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGGALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAKVFV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58404-1", "uniprot_id": "STRN4_MOUSE", "id": "P58404-1", "name": "Striatin-4", "aln": "MMEERAAAAVASAASSCRPLGSGTAPNPTAAAPASSPAPGPGPVGKGG---GGGGSPGPTAGPEPLSLPGILHFIQHEWARFEAEKARWEAERAELQAQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKK-TDLSEQVSNGPVESVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGR-SLELNGAGEPVEGAPRASPGPGGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLEQIPFLQNCEDEDSDEDDE-----------LDSVQHKKQRVRLPSKALVPEME--DEDEEDDSEDAINEFDFLGSGEDGEGSPDPRRCTSEGNPHELESRRVKLQGILADLRDVDGLPPKVTVPPPGTPQPRPHEG-SFGFSSDVFIMDTIGGGEVSLGDLADLTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAKVFV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRL3-1", "uniprot_id": "STRN4_HUMAN", "id": "Q9NRL3-1", "name": "Striatin-4", "aln": "MMEERAAAAVAAAASSCRPLGSGAGPGPTGAAPVSAPAPGPGPAGKGG---GGGGSPGPTAGPEPLSLPGILHFIQHEWARFEAEKARWEAERAELQAQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKK-ADVSEQVSNGPVESVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGR-SLELNGAVEPSEGAPRAPPGPAGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLGQIPFLQNCEDEDSDEDDE-----------LDSVQHKKQRVKLPSKALVPEME--DEDEEDDSEDAINEFDFLGSGEDGEGAPDPRRCTVDGSPHELESRRVKLQGILADLRDVDGLPPKVTGPPPGTPQPRPHE--------DVFIMDTIGGGEVSLGDLADLTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEPAHIVASFRSGDTVLYDMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAKVFV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PC77-1", "uniprot_id": "A0A8M9PC77_DANRE", "id": "A0A8M9PC77-1", "name": "", "aln": "-MEAERSGGMAGGTS-QSPAGSGTGRNPNGPKAVLGPAPSAVAAAAAGPMAGSSQSRDQQDGDAGLSLPGILHFIQYEWSRFQAEKYRWEAERDELRAQVAFLQGERKGQENMKQDLVRRIKMLEYALKQERAKHQKLKSGTDQSPGEKKPETEAEPIPNGPANSDSEPTNQMPWKEGRQLLRKYLEEVGYSDTILDMRSKRVRSLLGRNSPEANGP-PSSEPTTEPEPHVGVGGGGESLLVRQIEEQIKRRAGKESSKERMGSSVLDKIPFLRGCEDDDEDDSDEEEDFQGMTTDCIDGRKNKKSRAKMGGEPMTTDLDPEDEDDEDDSEDALGEFDFLASGEEGEGAGEAR-ISGDGRELGSENRRNKLQGIMSDF------PPKPTPPPSIPGQARSGEGGALGFSSDVFILDAVGGGDMNLGELADLTVANDNDLTIDLQDSREEFKKTWNPRFTLRSHFDAIRALSFHPSQAVLLSASEDGTLKLWNLNKAMHSKKNAALDVEPIYTFRAHSGAVLSLAMGEEGESCFSGGLDGTIRGWKIPDLNVDPYDNYDPGVESSVLSGHEDAVWGLAFSSSLQRLASCSADGTVRIWDPHNSSP-CVSVFNKEKEHGTPTSVAFVNADPSQVVVSFDGGETLLYDLNTEQSIMVLETQTKDGSELINRVVSHPSQPISITAHENRTIRFLDNNTGKVIHSMVAHLDAVTCLATDPKGTYLISGSHDCSVRLWMLDNRTCVQEITAHRKKHDEAIHDVAFHPTQPFIASAGADALAKIFV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05040-1", "uniprot_id": "FAR8_YEAST", "id": "Q05040-1", "name": "Factor arrest protein 8", "aln": "------------------------------------------------------MAINQAHVHPHYTLPGVMHYLQTEFTKNERDRITWELERSEMKARIAELEGENR---------------------DLKHQLNQIQSKAVSPEGEKE----EKHVPDSLLQS------KLAVQENVKEIIYLLKGPNTVNQLESLNSREAGSELHD------------------------------LEKLNVNTPKEEGSAKTNGMDILNNALLDTKPNPK--------------------------------------------------QGPSESPSPTKVKSLFSTANKRENNETISKIHSELSKVDIIS---------------------------------------------------------SYGDCMALYDADTKSLEIHQVDAN--LNSKLLKKISLGQDSDIMK--FFWVSTSKLLVIEKSFHLKLFSISSASLIS-DVDLLQDSEQPFSSSD--IINIDFKNKWLLIASK-NKSQIRIWELDNIEAPEDVPINIKETYEITHDNDDDDS-----NDSTNILDCILGITEKSLILLSSNPYQLTIYDFEGKLLQKIDLKIDTILSG---KPEEEGYHLFLDRKTSKLLIQLS-----------------NERLLVYSFDKKKVVLKEQLTPSSTLPIQLDLNDSIITVSYSNGDFEFRNLENLKP---SIDEFVVADINFSERKEPVVFSSNLIVDSTPVLITVNKNNEVLLHKIKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :***::*::* *::: : :: ** ** *::*::* *:**.: : : : :::: : ***: : :.:. :* : :*. : : *: . : : .:.*:.. * * * ::: :. :. .. : :..::* * : : .:* .. .::.:.:. *. : . . *: * :: :.* . *:. ::.. :::* .. * :: * * : ** .:. ***:.:..* . :. * :. .* : :: : : .: * .. *: *:: ::. : : .: * .: .* . * : .*.. : : : .: : . .. . * :: * :. :: *. .: : : :.:.: : : :: * . .: .*: . .:* : : . .: . :*: . .: :.**: : ..: :*: : : : ", "identical_positions": 63, "similar_positions": 205, "identity": "8.07%" }, { "cls_id": "homologset.agr.MGI:2142364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BLH7-1", "uniprot_id": "HIRP3_MOUSE", "id": "Q8BLH7-1", "name": "HIRA-interacting protein 3", "aln": "MAPGDEMRKFTRSFFRACPDLSSVTHAIVRQKFLIHVGRDHLEPEEKQALKRLVEEELPKMQADAG-TREGKPDFIK-VKRSPAPCSDPKKKRFRFNSESESSSSPSSPDGSGPSTKN------RTTKKTCLRRALKKAVESTDEDHQTDLDAKMGLEESSEGEAEGSVRSGKVTE----EEEDMKQEQKGQVRKQAGAKDKQVPLKADRKQVREESGSSEEEAVLQRAK-VEGSTGANCQEESE-ESGEESPAKKKELSE------------------PRSRSNRAERTARERKSYKQKSRPGRPTGGLRDSEAEKEGGTVGSGDSSEEGEAEKEGGTVGSGDSSEKGEAEKEEGTVGSGDSSEEGEEHSVKRKSKVRTQTESGRRQNTSSRDDSNSTQEQAAAQGTTKSGSLGSSNGD-SDTEREVSDSQAGQNTKEERKSRSSNKSSKNGQARSCSSSSDSSPEPTGQKGKARSSSSSSDSGPEPTGRKAASRCGEDHPAVARLKRYIRACGAHRNYKKLLGSCSSHKARLSVLRAELEALGMKGNPSLEKCRALKLQREEAAEVAALDVANIISSTGRPRRRNAWNPSGEGTSPGETYRRTLDSEEEQPRQAPPDWSHMRDIISSDGDSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PSX7-1", "uniprot_id": "E9PSX7_RAT", "id": "E9PSX7-1", "name": "", "aln": "MAPGDEMLEFTRSFFRACPDLSTVTHSIVRQKFLIHVGRDHLEPEEKQALKRLMEEELLKMQADAG-TREGKPDFIK-VKRSPAPCSHPERKRFRFNSESESSSTPSSPDCSGPPTKN------NTTKKACPRRTLKKAVESTDEEQQTDLVAKMGLEESSEEEEEGSVRSGEVWKAEDTEDDDVRKEQKGGVRKKAGAKNKPAPHKADRKQAREESGSSEEEAVQNRAK-VERRTGAKCQEESE-DSEDEILAKKSEHRE------------------SRLKSSKAGRTASGRKSSKQKSRAGRPTGGLGDSEEKKEGDAVSSGDSSGE-------------------------------------EEPLAKRKSKDKTQTESGRRQSTSSEDD-DGRQVQAATQGTTKTGSLGSSNGD-SGTEREVSDSQAGQNTKEERKSRSSKKSSKNGKARSSSSSSDASPEPTGQKAGSR-------------------RCGEDHPAVVRLKRYIWACGARRNYKKLLGSCGSHKERLNVLRAELEALGMKGNPSLEKCRALKQHREEAAEVASLDVANIISSSGRPRRRNAWNPSGEAISPGELYHRTLDSDEERPRQAPPDWSHMRGIISSDGESS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BW71-1", "uniprot_id": "HIRP3_HUMAN", "id": "Q9BW71-1", "name": "HIRA-interacting protein 3", "aln": "MAREKEMQEFTRSFFRGRPDLSTLTHSIVRRRYLAHSGRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPERKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDLPAQRG-EESSEEEEKGYKG---------------KTRKKPVVKKQAPGKAS-----VSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKE--AASSGDDSGRD------------------------------------REPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSG-------------------RRGEDHPAVMRLKRYIRACGAHRNYKKLLGSCCSHKERLSILRAELEALGMKGTPSLGKCRALKEQREEAAEVASLDVANIISGSGRPRRRTAWNPLGEAAPPGELYRRTLDSDEERPRPAPPDWSHMRGIISSDGESN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .** :*******. ****::**:***:::* * **.*************:**** ***.* . :**.* *: * **.*:***.*::***********.* .**** **.:** .:*: **: * . **:**::* ** *: * ***** * :* : .:* *:*:* .* . ..***.**** .** *.* . ** ** .*::. :*** :* :* *:*.* * .* :*. ::* .:* ****:. * *. ..* :** :..***.* . .* .:***: :** :.*:* . **.*: :. : :.:::*: * . ***:.*: *. *******:** ..: ***.***:***::*::**.*****.***..* *. : * ******* ****** ****:********** *** **.:************.*** ****** :********:********.:******.**** **. .*** *:*****:**:** *********.******:*.", "identical_positions": 304, "similar_positions": 133, "identity": "47.95%" }, { "cls_id": "homologset.agr.MGI:2142403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C6B1-1", "uniprot_id": "S35E1_RAT", "id": "P0C6B1-1", "name": "Solute carrier family 35 member E1", "aln": "---------------------------------------------MAAAAAAGPGAGAGIPGASGG-GGAREG------ARVAALCLLWYALSAGGNVVNKVILSAFPFPVTVSLCHILA----------LCAGLPPLLRAWR--------VPPAP---------PVSGPGPSPHPASGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKE--KQSTKVYLSLVPIISGVLLATVTELS----------FDVWGLVSALAATLCFSLQNIFSKKVLRDSRIHHLRLLNILGCHAVFFMIPTWVLVDLSTFLVSSDLAYVSQWPWTLLLLVVSGFCNFAQNVIAFSILNLISPLSYSVANATKRIMVIAVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARRHLLPVSTSDLSNREHLRSPMEKPHNGALFPQQGDFQY-RNILLTDHFQYSRQGHPNSYALSRHDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CD26-1", "uniprot_id": "S35E1_MOUSE", "id": "Q8CD26-1", "name": "Solute carrier family 35 member E1", "aln": "---------------------------------------------MAAAATAGPGAGAGVPGAGGG-GGAREG------ARVAVLCLLWYALSAGGNVVNKVILSAFPFPVTVSLCHILA----------LCAGLPPLLRAWR--------VPPAP---------PVSGPGPGPHPASGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKE--KQSTKVYLSLVPIISGVLLATVTELS----------FDVWGLVSALAATLCFSLQNIFSKKVLRDSRIHHLRLLNILGCHAVFFMIPTWVLVDLSTFLVSSDLAYVSQWPWTLLLLAVSGFCNFAQNVIAFSILNLISPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARRHLLPISTSDLSSREHLRSPVEKPHNGALFPQQGDFQY-RNILLTDHFQYSRQGHPNSYALSRHDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96K37-1", "uniprot_id": "S35E1_HUMAN", "id": "Q96K37-1", "name": "Solute carrier family 35 member E1", "aln": "----------------------------------------------MAAAAVGAGHGAGGPGAASSSGGAREG------ARVAALCLLWYALSAGGNVVNKVILSAFPFPVTVSLCHILA----------LCAGLPPLLRAWR--------VPPAP---------PVSGPGPSPHPSSGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKE--KQSTKVYLSLIPIISGVLLATVTELS----------FDMWGLVSALAATLCFSLQNIFSKKVLRDSRIHHLRLLNILGCHAVFFMIPTWVLVDLSAFLVSSDLTYVYQWPWTLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARKHLLPVTTADLSSKERHRSPLEKPHNGLLFPQHGDYQYGRNNILTDHFQYSRQSYPNSYSLNRYDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR50-1", "uniprot_id": "S35E1_DROME", "id": "Q9VR50-1", "name": "Solute carrier family 35 member E1 homolog", "aln": "--------------------------------------------------------------MLGKRTGSRHI------AVVLLMCLFWYVISSSNNVIGKMVLNEFPFPMTVTLVQLCS----------ITLYSGPFFNLWR--------IRKYQ---------DIPRP---------------YYYRLIVPLALGKLLASVTSHISLWKVPVSYAHTVKATMPLFTVVLTRVFFGE--KQPTLVYLSLLPIITGVGIATVTEIS----------FDMMGLISALISTMGFSMQNIFSKKVLKDTNIHHLRLLHLLGKLSLFIFLPLWLYMDSFAVFRHTAIKNLDYR--VIALLFADGVLNWLQNIIAFSVLSLVTPLTYAVASASKRIFVIAVSLLILGNPVTWVNCVGMTLAIVGVLCYNRAKQLTRGRE-QPTLPLSQTSYVKYSPLEQQADPYYRGSVN---GKLSNGLHRTPGNSLLANGSGMPSGTATRLLFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39542-1", "uniprot_id": "YJT3_YEAST", "id": "P39542-1", "name": "Uncharacterized transporter YJL193W", "aln": "-------------------------------------------------------------MFQQLSASIRHN------AHIIFLCISWYFISSLASQVTKQVLTVCPLPLFLGEFQFIYTAVLAWFTCYIAYSFPGFYRIFPNGTFPEYYIDDRE---------TSRAARKESKLSSLIIPPSKPILQTVLPLGLFQFVGKYFGHTATSLVPVSTVASIKTLSPMFILLLQKILKISTLKITLTLIFSLCTLVLGVWIIVQEDNRSPASSNELREFSKYGVICAMISMFIFVLQNIYGKTVFT-YRSQTDESQSNSGFSRQESPLPLYEKLDEKLVAKKKPKSYDKLT--LMIYISLVGFCLSFGWFITLEFPVLFR-YFFQINSSSTVIKAFPVSLFLLNG--TFHFIQAMITFHLLGEVSTLTYSIANLMKRFAIIAVSWVFIGRRITWLQVFGLVLN-----------------TLGLFLYERCTSQSKIKAKIRPE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22215-1", "uniprot_id": "SLY41_YEAST", "id": "P22215-1", "name": "Uncharacterized transporter SLY41", "aln": "MIQTQSTAIKRRNSVHKNLFDPSLYQIPEPPRGGFQHQKKEYSKETFSNQVFGYDITSLKKRFTQLFPSNIQGYLPEVDLRITIICSIWYVTSSISSNLSKAILRTFNHPIALTELQFLVS-------AVLCVGFASIVNLFRLPRLKHTKFSKALNSFPDGILPEYLDGNFRSSILHKFLVPSKLVLMTTFPMGIFQFIGHITSHKAVSMIPVSLVHSVKALSPIITVGYYKFFEHR--YYNSMTYYTLLLLIFGVMTTCWSTHGSKRASDNKSGSSLIGLLFAFISMIIFVAQNIFAKNILTIRRKVG--------------ILPSSSTDDVTSKEGQPSLDKTRFSPLQVDKITILFYCSCIG--FSLTLLPFLTGELMHGGSVINDLTLETVALVAIHG--IAHFFQAMLAFQLIGLLSSINYSVANIMKRIVVISVALFWETKLN-FFQVFGVILT-----------------IAGLYGYDKWGLSKKDGRQA---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :* ** *: . : * :* *: : :: : : . : . .*:.: : .. .* : :*** . ::*: *: : :.: :* :: ** . *:: *: : : * ***:.*.:: . :* * : : ::: . :. . . : .*:*. : . .* : . :. :.:: . . . . ", "identical_positions": 29, "similar_positions": 81, "identity": "5.79%" }, { "cls_id": "homologset.agr.MGI:2142433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKG2-1", "uniprot_id": "A0A8I6AKG2_RAT", "id": "A0A8I6AKG2-1", "name": "", "aln": "MAGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRG----------------ATPPAPPRVPRGGP--------------AAPPPTPAPPPAP----VAAPTRAPR------AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAAAPPAGPRRAPPPAVAAREP----------------PAPPQQQQPPPPQPQPPPEGGAARAGGPAR-------------------------------PVSLREVVRYLGGSGGASG-RLTRGRVQGLLEEEAAR-GRLERTRLGALALPRGDRPGRAPPAASARAARSKRGGEER-VFEKEEEDDEEDDEEEEEDNVSEGSEVPESDRPAGAQHHQINGERGPQSAKERVKEWSPCGPFQGQDEGRGPAPGSCTHQVFSMTAMNKEGGSACVTAAPDSPSPVPLPPGKP--------------------------------ALPGADGTPFGCPPGRKEKPT--------------DPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPDGFLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YXK1-1", "uniprot_id": "SAMD1_MOUSE", "id": "D3YXK1-1", "name": "Sterile alpha motif domain-containing protein 1", "aln": "MAGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRG----------------ATPPAPPRVPRGGP--------------AAPPPTPAPPPAP----VAAPTRAPR------AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAAAPPAGPRRAPPPAVAAREP----------------PAPPQQQQPPPPQPQPPPEGGAARAGGPAR-------------------------------PVSLREVVRYLGGSGGASG-RLTRGRVQGLLEEEAAR-GRLERTRLGALALPRGDRPGRAPPAASARAARSKRGGEER-VFEKEEEDEDEDEEEEEEDNVSEGSEVPESDRPAGAQHHQINGERGPQSAKERVKEWSPCGPYQGQDEGRGPAPGSCTRQVFPMTAVNKEGGSACVGAAPDSPSPVPLPPGKP--------------------------------ALPGADGTPFGCPPGRKEKPT--------------DPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPDGLLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6SPF0-1", "uniprot_id": "SAMD1_HUMAN", "id": "Q6SPF0-1", "name": "Sterile alpha motif domain-containing protein 1", "aln": "MAGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRG----------------ATPPAPPRAPRGAPAAA---------AAAAPPPTPAPPPPPAPVAAAAPARAPRA----AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP--------PAPPQQQQPPPPQPQPPPEGGAVRAGGAAR-------------------------------PVSLREVVRYLGGSGGAGG-RLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEER-VLEKEEEEDD-DEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKP--------------------------------ALPGADGTPFGCPPGRKEKPS--------------DPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPDGFLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IFY9-1", "uniprot_id": "A0A0R4IFY9_DANRE", "id": "A0A0R4IFY9-1", "name": "", "aln": "--------------------------MSEPYREWILGSIDSLRSRKARPDLDRICRMVKRRHGSDWDRTRSELEKLIEEQAVLKVNYKGSVSYRNAAKVLRGRRR----------------TEQSK----------------------------CAGKQPSP------------------------ADWSAGDSAQGPVDEDHMEDMEDEMSTTAGMDSSMDEEGDESSLDAMCAQST--------------------------------------ADSGISMS-------------------------------PITSSNTSLPLPSPTSSKN-SPTHDDLR----QEADS----------AYTLPEHMQPSGQQDTGCVVLVQQPQAICLP-VLKVEDGLQAEESTLTHDELMSERTVTLD---------EAVKSDGGSHAVSDHTEEGEIC---------------------------NKESKSVAEEETINSGE---INNGND--------------------------------VIK-------------EEISQ--------------DPLLWSVADVARYFTSVGFPEQALAFRTQEIDGKSLLLMQRSDVLTGLSIRLGPALKIYENHVKVLQRSHFQEDG-RLFSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BB29-1", "uniprot_id": "A0A8M2BB29_DANRE", "id": "A0A8M2BB29-1", "name": "", "aln": "-------------------------MSEPKYQEWILETIDSLRSRKARPDLERICRMVRRRHGSDPDQTRAELEKLIQEQTVLKVSYKGSISYRNAAKVQRKCRKRPEQTTDSSSGSGESVAEQTKHAAFTNTGDSALSLTDQEEEESGDKEPEEPRVSPSPDPPLQSSPSTLEKEDKILPLHSGNSLVSCGATGCSAGSEKASASKERRSVSAAGGGGSGPRDASSAGEEMLSAGHEGTDEEEEKEQKTCSSVSSPQKNRLSAPSKLKPGVKGSAVRGSDSPEENSTDLGDRLMDAVRSMSERHRGSAATRGHAPPGLKEILDYLCTQKGMPGEKLTRNRVKVVLEREIER-GRLRRTRLGHITLPARGMGAAKPSARLLKSALQDRHLAKKEELKDEDGMEVESEGNGTEEPTAEDLPETVPDEDPVSVKTGTEPPSPEMEAESDHATRSPMMTCEGESQTSSSLQLSNHCSILQQADVGESQEQTMCAEAEDSGTEKPADPSDQRHPSVEDQMLVMSETVKPPSSIPIRNCCKLEVGVSSCLLTPSASPGAAEERGMNEGIGFVKSESSVVSPVDWTVADVASYFTAAGFPEQAIAFRTQEIDGKSLLLMQRNDVLTGLSIRLGPALKIYERHVKVLQKTHFQDDE--AFC-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**** :*************:******:****.: ::**:******::::**:*.****:******:* * : . . *.* : * * : .. : .:* : : :.* . .. . * : * . . *:. :: .* :** . : . : :: *: : .. :: :* : ... .:. . :* .. : :* .*: *:* **. *** .****** **: *************.******************.*:****: **::* : ", "identical_positions": 122, "similar_positions": 85, "identity": "18.63%" }, { "cls_id": "homologset.agr.MGI:2142454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91W78-1", "uniprot_id": "USB1_MOUSE", "id": "Q91W78-1", "name": "U6 snRNA phosphodiesterase 1", "aln": "MSSAPLVGYSSSGSEDEAEAVAAGRSKP-------------GTGFHRCGQNPVPSEKLPVPDSVLSMF--PSTEEGPEDDSAKHGGRIRTFPHERGNWATHIY-----IPYEAKEDFRDLLDALLPRAQMFVPRLV----LMEEFHVSLSQSVVLR-----HHWILPFVQVLKDRMASFQRFFFTANRVKIYTNQEKTRTFIGLEVSSG--HAQFLDLVSEVDRAMKEFDLTTFYQ----DPSFHISLAWCVGDASLQLEG--QCLQELQEIVDEFEDSEMLLRVLANQVRCKSGNKFFSMPLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0I5-1", "uniprot_id": "USB1_RAT", "id": "Q5I0I5-1", "name": "U6 snRNA phosphodiesterase 1", "aln": "MNAAPLVGYSSSGSEDEAEAVAAGRSKP-------------GSGLHRCGQNPLPSQRFPVPDSVLNMF--PSTEEGPEDDSARHGGRIRTFPHERGNWATHIY-----IPYEANEEFQDLLDVLLPRAQMFAPRLV----QMEEFHLSLSQSVVLR-----HHWILPFVQVLKDRMASFQRFFFTANRVKIYTNQEKTRTFIGLEVSSG--HAQFLDMVSEVDRVMKEFDLTTFYQ----DPSFHVSLAWCVGDARLQLEG--QCQQELQEIVDEFEDSEMLLRVLAEQVRCKSGNKFFSMPLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQ65-1", "uniprot_id": "USB1_HUMAN", "id": "Q9BQ65-1", "name": "U6 snRNA phosphodiesterase 1", "aln": "MSAAPLVGYSSSGSEDESE--DGMRTRP-------------GDGSHRRGQSPLPRQRFPVPDSVLNMF--PGTEEGPEDDSTKHGGRVRTFPHERGNWATHVY-----VPYEAKEEFLDLLDVLLPHAQTYVPRLV----RMKVFHLSLSQSVVLR-----HHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTSG--HAQFLDLVSEVDRVMEEFNLTTFYQ----DPSFHLSLAWCVGDARLQLEG--QCLQELQAIVDGFEDAEVLLRVHTEQVRCKSGNKFFSMPLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DEF6-1", "uniprot_id": "USB1_DANRE", "id": "Q6DEF6-1", "name": "U6 snRNA phosphodiesterase 1", "aln": "----MIVNYSSSSSEEESGSSSSPSGKRQKLDTETSEALDHGSAQRKVCKSSHLTPRLPLPESVKEMF--RDSEELWTDKSEEHGGRLRSFQHERGNWATYVF-----FPYDPEEAFLEVLNKMMAAAEAHDIPLT----VSEEFHLSLSKTVVLR-----HHWIQPFVQSIRTSLTHFQKFYCVAYKLKVYSNAEKTRTFLGMEVSTG--TPHLLELSKIVDETMKEFNLSTFYE----DPSFHISLAWCVGDQTERLKK--ACLLELQGLIDAHEDGPFHARLNCNELRCKTGNKVFVFPLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHB3-1", "uniprot_id": "USB1_DROME", "id": "Q9VHB3-1", "name": "U6 snRNA phosphodiesterase 1", "aln": "---MALVDYGGSSSSASEDEDCTENIQT---------------PALITLKRPALPKAATLLGPKKPKP--EEFVEDVVDDPAEHGGRMRSFKHERGNWATYVY-----VPATACVDQLEEFQTEAIARLEPHLELQ----PNESLHLSLSRTVVLQ-----YHQIDEFSRSLQSALNSSAGFAATLQGLRIYTNEERTRTFIAAPLDAAF-VEKMTAILQPIDQVMLDYRLQQFYD----PASFHVSLLWCVGDQETLLN---EKLTELKELLDDQDK----LCLAVNEVHLKCGNKDFTYSLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12208-1", "uniprot_id": "USB1_YEAST", "id": "Q12208-1", "name": "U6 snRNA phosphodiesterase 1", "aln": "-MEFISADYSSSDGSDTESESSNKSEVQ------------IEYTEKTCIQKADSTDLPAIPDSIILKYHIPPNLQKYEHQDMNMSRFWRSFTYFEWRPTPAIHRQLQKIICKYKETFMKQEYTNPYQLVDFDPLFISHLGAPKPLHVSLTRSLLFETEEQRHVFIQEMRNGLRNNEITPFKLQICSY-PKLYISERANTLYLGLPVSECPNKAQISPFKTIIAEALQKSGISNYQDLIVSRQNLHVSIAIASNPSKATLKRYQQLNETMGALLLLNNDFAYKLEFLVNSIYCDENRHSIRIPFN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*..*... : . .: . : .. . . *:* : . . :. :. . . : : :*:**::::::. : * : . :: : ::* . . . ::. : :: : : ..: . : : : .:*:*: . . *: : :: :. . :.: . ..: : .::", "identical_positions": 12, "similar_positions": 88, "identity": "3.95%" }, { "cls_id": "homologset.agr.MGI:2142489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LV46-1", "uniprot_id": "I23O2_RAT", "id": "F1LV46-1", "name": "Indoleamine 2,3-dioxygenase 2", "aln": "MEAQRQD-------GKLASSLSLGKYHISEEYGFLLP-NPLEELP-DHYKPWMEIAHRLPHLIESHQLQAHVYE---MPLLDCRFLTSYREQRLAHLVLAAITMGFVWQEGEAQPQKVLPRTLAIPFVEVSRSLGLPPILVHSDLVLTNWTK-----RNPEGPLEIGNLETIISFPGGESLQGFILVTVLVEKAAVPGIKALVLGVEAIRQHSQ--DTLLEALQQLRLSIQDITRALAQMHDYVDPEIFYLVIRIFLSGWK--DNPVMPVGLVYEGVSTEPLKYSGGSAAQSSVLHAFDEFLGIQHCK---------ESVDFLHRMRDYMPPSHKAFLEDLHSAPSLRDYILDSGPG-GCLMAYNQCVEALGELRSYHINMVARYIISAASKARSRMLT---------------RLS--PHALEDRGTGGTAVLSFLKSVREKTMEAILCPGA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0V5-1", "uniprot_id": "I23O2_MOUSE", "id": "Q8R0V5-1", "name": "Indoleamine 2,3-dioxygenase 2", "aln": "MEPQSQS-------MTLEVPLSLGRYHISEEYGFLLP-NPLEALP-DHYKPWMEIALRLPHLIENRQLRAHVYR---MPLLDCRFLKSYREQRLAHMALAAITMGFVWQEGEGQPQKVLPRSLAIPFVEVSRNLGLPPILVHSDLVLTNWTK-----RNPEGPLEISNLETIISFPGGESLRGFILVTVLVEKAAVPGLKALVQGMEAIRQHSQ--DTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSGWK--DNPAMPVGLVYEGVATEPLKYSGGSAAQSSVLHAFDEFLGIEHCK---------ESVGFLHRMRDYMPPSHKAFLEDLHVAPSLRDYILASGPG-DCLMAYNQCVEALGELRSYHINVVARYIISAATRARSRGLT---------------NPS--PHALEDRGTGGTAMLSFLKSVREKTMEALLCPGA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZQW0-1", "uniprot_id": "I23O2_HUMAN", "id": "Q6ZQW0-1", "name": "Indoleamine 2,3-dioxygenase 2", "aln": "MEPHRPN-------VKTAVPLSLESYHISEEYGFLLP-DSLKELP-DHYRPWMEIANKLPQLIDAHQLQAHVDK---MPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVLPRNLALPFVEVSRNLGLPPILVHSDLVLTNWTK-----KDPDGFLEIGNLETIISFPGGESLHGFILVTALVEKEAVPGIKALVQATNAILQPNQ--EALLQALQRLRLSIQDITKTLGQMHDYVDPDIFYAGIRIFLSGWK--DNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSK---------ESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQD-HLLTAYNQCVQALAELRSYHITMVTKYLITAAAKAKHGKPN---------------HLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47125-1", "uniprot_id": "I23O_YEAST", "id": "P47125-1", "name": "Indoleamine 2,3-dioxygenase", "aln": "MNNTSITGPQVLHRTKMRPLPVLEKYCISPHHGFLDDRLPLTRLSSKKYMKWEEIVADLPSLLQEDNKVRSVIDGLDVLDLDETILGDVRELRRAYSILGFMAHAYIWASG--TPRDVLPECIARPLLETAHILGVPPLATYSSLVLWNFKVTDECKKTETGCLDLENITTINTFTGTVDESWFYLVSVRFEKIGSACLNHGLQILRAIRSGDKGDANVIDGLEGLAATIERLSKALMEMELKCEPNVFYFKIRPFLAGWTNMSHMGLPQGVRYG-AEGQYRIFSGGSNAQSSLIQTLDILLGVKHTANAAHSSQGDSKINYLDEMKKYMPREHREFLYHLESVCNIREYVSRNASNRALQEAYGRCISMLKIFRDNHIQIVTKYIILPSNSKQHGSNKPNVLSPIEPNTKASGCLGHKVASSKTIGTGGTRLMPFLKQCRDETVATADIKNEDKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . * * ** .:*** .* *. .:* * **. ** *:: : * : *. :* . ** * *: *. :: .::* .* * .***. :* *::*.:: **:**: .:*.*** *:. : * *:: *: ** :*.* . * **:. .** . . :: : .** . .: :::.*: * :*: ::::* :*. :*::** ** **:**. .: :* *: * . : :**** ***::::::* :**:.* .. .:* .*:.*** .*: *: .:. . .:*:*: .. . **.:*:. * :*. ** :*::*:* .: : . : : ***** ::.***. *::*: : ", "identical_positions": 114, "similar_positions": 137, "identity": "25.0%" }, { "cls_id": "homologset.agr.MGI:2142491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3R0-1", "uniprot_id": "EST2A_RAT", "id": "Q8K3R0-1", "name": "Pyrethroid hydrolase Ces2a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLARLP------------------------GWLYVVACG----LLLLLQHVHG---------------------------------------------------------QDSAS------------------------PIRNTHTGQVRGSFVHVKDTKSGIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQT-DIMNLDGIKEMKLTVHPTPMSEDCLYLNIYTPAHAREGSN-LPVMVWIHGGGLVLGSAS--MNDASTLAATEEIVIVSIQYRLGVLGFFSTGDQNARGNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGSAGGTSVSSHVVSPMSKGLFHGAIMQSGVALLPDLISDKSEVVYKTVANLSGCEAP---DSEALIRCLRAKSKQEILAINQ-----------VFKMIPG--VVDGKFLPKHPQELLASGDFHPVPSIIGINTDECGWGIPVFLGLDHIIKKITR---ETLPTVLKSTAAQ-MMLPPECIDLIMEEYMGDTENPETLQEQ-FRHMLGDFMFVIPALQVAHFQR--SQAPVYFYEFQHLP------SFIKQVRPSHVKADHGDDILFVFGSYLWGMTF----DLTEEEELLKRRVMKYWANFARTGNP-NGEDLPHWPVLDHDEQYLQLNTQPAVGRALKARRLQFWTKTLPQKIQELKGSQSKHAEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZR3-1", "uniprot_id": "EST2A_MOUSE", "id": "Q8QZR3-1", "name": "Pyrethroid hydrolase Ces2a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLARLP------------------------GWLCVVACG----LLLLLQHVHG---------------------------------------------------------QDSAS------------------------PIRNTHRGQVRGSFVHVKDTKSGVHAFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQP-DIMNLEDAKEMNLILPPISMSEDCLYLNIYTPTHAQEGSN-LPVMVWIHGGGLVVGSAS--MNDVSKLAATEEIVIVAIQYRLGVLGFFSTGDQHARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISDTSEVVYKTVANLSGCEAT---DSEALIHCLRAKSKQEILAINQ-----------VFKMIPA--VVDGEFLPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMFMGLDHIIKNITR---ETLPAVLKNTAAR-MMLPPECSHLLVEEYMGDTEDPETLQAQ-FREMLGDFMFVIPALQVAHFQR--SQAPVYFYEFQHLS------SFIKHVRPSHVKADHGDDVAFVFGSYLWDMNL----DLTEEEELLKRMMMKYWANFARNGNP-NSEGLPSWPVLDHDEQYLQLDTQPAVGRALKARRLQFWTKTLPQKIQELKGSQDKHAEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00748-1", "uniprot_id": "EST2_HUMAN", "id": "O00748-1", "name": "Cocaine esterase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLHRLR------------------------ARLSAVACG----LLLLLVRGQG---------------------------------------------------------QDSAS------------------------PIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-LPVMVWIHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQV---DSEALVGCLRGKSKEEILAINK-----------PFKMIPG--VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDR---EASQAALQKMLTL-LMLPPTFGDLLREEYIGDNGDPQTLQAQ-FQEMMADSMFVIPALQVAHFQC--SRAPVYFYEFQHQP------SWLKNIRPPHMKADHGDELPFVFRSFFGGNYI----KFTEEEEQLSRKMMKYWANFARNGNP-NGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZ17-1", "uniprot_id": "A0A8M9PZ17_DANRE", "id": "A0A8M9PZ17-1", "name": "", "aln": "MAMRESAVLSLCILIAVTLQNSVKAEDGPILQTNSGALKGLQMKARGKDTVIHSYLGIPFAKPPVGPLRLAPPQPAEKWEGVRDATKQPLMCLQDRQLVEDLVANLSAKVDMVDSSEDCLYLNVYTPSKPGRNDKLPVMVWIHGGGFTTCSASLFDGHVLAAYQDVVVVVIQYRLGLLGFFSTGDENAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSLHVLSPLSANLFHRAIAESGTAAMEAIMNVNPLPIAQAIGNASGCDISSTKKIVDCLMQKSEVEILKITMENPLFRFGVTIDGQFLPRPAAELFQSQQFNKVPLMTGVTDDEIGFVLPNYLLPPDWINGLDLESILPLLTVFNPALQDQSVLELLLNEYLGTSPDRIRIRDGFREMLGDFMFNIPARQTASYHRDAGAPVYVYEFRHPPSVLQRKRPSFSGSDHGDEIVFVFGYCFSEGPIGMAENLSDEEDELCRTTMAYWGNFAHTGNPNGPGLTSWPEFGDEAEYLSIGLDPKASTDLKGKHFTFVTQTFPRILSERKEGPVVNTKLGSLRGSYMMAKGKDSVISSYFAIPFAKSPVGPLRLTPPQPADAWQGVRDATKQPPMCLQPKEVMVDLLATMPLKTEFPEVSEDCLYLNIYTPSKPGDNKKLPVMVWIHGGGLAFGSASIFDAHALAAYQDIVVVMVQYRLGLLGFFSTGDEHAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTVFGESAGGVSASLLVLSPLSANLFHRAIAESGTAAMNAIMSPDPLSTARSLGNVSGCDISSTKKIVDCVMQMTEEDILKIAREQVLLRFGVTVDGQFLPKSVDELLQSQEFSKVPLMTGVTDDDGGFTLPEFIAPPGWRDGMTKDQIMPFLPTYNYDLQDPGLAEIVLKEYLGATTDKIKIRDGFREIVGDFFFNLPARKLANYHRDTGAPVYMYEFQHPAYIFQNKRPSFVGCDHGDELLFVFGYCFGNGHIKVEGELSKEEQELCKTTMAYWGNFARTGNPNGPGLVEWPKYGAEAEYLGIGLEQKSSKNFKGNHFHFMIEKLPQIIKEWKEGPVVETKLGSLRGAFLTVKGKDTIVNSYLGVPFAKPPVGPLRLARPQAAEKWQGVRDATKQPRMCLQE-RQMTVTELEFLSMDVEVPEVSEDCLYLNIYTPVKPGQGDKKLPVMVWIHGGGLSLGSAS--MYDGSVLAAYQDVVVVLIQYRLGLLGFLSTGDEHAPGNYGFLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSTLILSPLASGLFHRAIAESGTAFWDGLVMADPFQRAQTAAKQCNCDSS---SSAKIVDCIMHWSEEEALECAK-----------KFQMMHFSVAVDSYFLPKPIEEIVEKQEFSKVPLINGINNDEFGFLLAEYFLGPEWMNGLKR---EQIAEALTLTYPD-PKDR-WIIDLVAKEYLGDTHDPIEIREV-YREMMGDVLFNIPALQLAKHHSG-TGAPVYLYELQHPP------SFLQKKRPSFVGVDHADDLYFIQGTCFAKAHLRISAPFTEEENELCRTVMAYWGNFAHTGSP-NGPGLTHWPEYENENEYLAIGLQQKPGKNLKHKHYEFMTKTLPELIRQGK---TKHSEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZA98-1", "uniprot_id": "A1ZA98_DROME", "id": "A1ZA98-1", "name": "Carboxylic ester hydrolase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIQQRMLQ----------------------LLLLGQLLAGPGP------------------------------------------------------------------FCAALAT--------------------VDQLTVCPPSVGCLKGTNLQGYQSER-FEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQK----------NYLLPTPVVYGDEDCLYLNVYRPEIR---KSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQ----RNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVNLWSHILNEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : .. :. .: . * : *: : . ..:::*:*:* **:* **:: *: *: *.: *:* : .******.:* * .. *****:****.: * *. : . . : ::::* : **** :**:** * **:* ** **:***.** ***: ***** **** :. ::** : **** .* **.* : . *: . .: : .: . : * . *: : . ** ::: . :* : * .* . : : : : * * . .*: : *: . : : : .::.* * * : : : : ***:*.::: :: . . . * *:: :: : : : .. * : : .: *: :**: *.* *. .*. . :.. : .. . : : . : * ", "identical_positions": 108, "similar_positions": 148, "identity": "6.57%" }, { "cls_id": "homologset.agr.MGI:2142501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LVG4-1", "uniprot_id": "F1LVG4_RAT", "id": "F1LVG4-1", "name": "Small integral membrane protein 19", "aln": "VLGDPMAGSYGMMADDGSIDYTVHEAWNEATNVYLIVILVSFGLFMYAKRNKRKIMRIFSVPPAGEMLSEPSFYDTMNRIRLRQQVEAHPVSRKYEYQQPQSQADSVQLSLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZU4-1", "uniprot_id": "SMI19_MOUSE", "id": "Q80ZU4-1", "name": "Small integral membrane protein 19", "aln": "-----MAGSYGVMADDGSIDYTVHEAWNEATNVYLIVILVSFGLFMYAKRNKRKIMRIFSVPPTEGMLSEPSFYDTVSRIRLRQQVEAHPVSRKYEYQQPQSQADSVQLSLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96E16-1", "uniprot_id": "SMI19_HUMAN", "id": "Q96E16-1", "name": "Small integral membrane protein 19", "aln": "-----MAGGYGVMGDDGSIDYTVHEAWNEATNVYLIVILVSFGLFMYAKRNKRRIMRIFSVPPTEETLSEPNFYDTISKIRLRQQLEMYSISRKYDYQQPQNQADSVQLSLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V921-1", "uniprot_id": "SMI19_DANRE", "id": "Q4V921-1", "name": "Small integral membrane protein 19", "aln": "------MGGYGVMADEESLDYSVHEAWNEATNVYLLVILVSFALLMYARKNKRKIMRIFTLPPTVGSSSEPNFYDSLQKVRLRQQLEMYSLARKYDQQQ--SQSESVQLSME", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.**:*.*: *:**:*************:******.*:***::***:*****::**: ***.***::.::*****:* :.::***: ** .*::*****:*", "identical_positions": 65, "similar_positions": 31, "identity": "58.04%" }, { "cls_id": "homologset.agr.MGI:2142523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q157S1-1", "uniprot_id": "CRTC1_RAT", "id": "Q157S1-1", "name": "CREB-regulated transcription coactivator 1", "aln": "MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQK---------SQYLQLGPSRGQYYGGSLPNVNQIGSSSMDLSFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTVYLSPP-ADTSWRRTNSDSALHQSTMTPTQAESFTGGPQDAHQK---RVLLLTVPGMEETGSETDKTLSKQSWDSKKAGS-----------------------------------RPKSCEVPGINIFPSADQENTAALIPATHNTG-----GSLPDLSTIHFPSP-------------------------------------LPTPLDPEEPPFPALTSS---------------------GSTG----SLAHLGVGGTGQGMNT--PSSSPQRRPAVVSPLSLSTEARRQQ-AQQVPPTLSPLSPITQAVAMDALSLEQQLP-------------------------YAFFTQAGSQQPPPQPQPPPPPPPVSQQQPPPP--QVSVGLPQGGPLLPSASLTRGPQLPPLAVTVPSTLPQSPTESPGQPPMGID------------------VTSAPALQ-YRTGAGSPATQSPTSPVSNQGFSPGSSPQ-------HTSTLGSVFGDAYYEQQMTARQANALSRQLEQF--NMMENAISSSSLYNPGSTLNYSQAAMMGLSGSHGG-LQDPQQLGYAGHGGIPNIILTVTGESPPSLSKELSSTLAGVSDVSFDSDHQFPLDELKIDPLTLDGLHMLNDPD-MVLADPATEDTFRMDRL--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68ED7-1", "uniprot_id": "CRTC1_MOUSE", "id": "Q68ED7-1", "name": "CREB-regulated transcription coactivator 1", "aln": "MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQK---------SQYLQLGPSRGQYYGGSLPNVNQIGSSSVDLAFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTVYLSPP-ADTSWRRTNSDSALHQSTMTPSQAESFTGGSQDAHQK---RVLLLTVPGMEDTGAETDKTLSKQSWDSKKAGS-----------------------------------RPKSCEVPGINIFPSADQENTTALIPATHNTG-----GSLPDLTNIHFPSP-------------------------------------LPTPLDPEEPPFPALTSS---------------------SSTG----SLAHLGVGGAGQGMNT--PSSSPQHRPAVVSPLSLSTEARRQQ-AQQVSPTLSPLSPITQAVAMDALSLEQQLP-------------------------YAFFTQTGSQQPPPQPQPPPPPPPVSQQQPPPP--QVSVGLPQGGPLLPSASLTRGPQLPPLSVTVPSTLPQSPTENPGQSPMGID------------------ATSAPALQ-YRTSAGSPATQSPTSPVSNQGFSPGSSPQ-------HTSTLGSVFGDAYYEQQMTARQANALSRQLEQF--NMMENAISSSSLYNPGSTLNYSQAAMMGLSGSHGG-LQDPQQLGYTGHGGIPNIILTVTGESPPSLSKELSSTLAGVSDVSFDSDHQFPLDELKIDPLTLDGLHMLNDPD-MVLADPATEDTFRMDRL--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UUV9-1", "uniprot_id": "CRTC1_HUMAN", "id": "Q6UUV9-1", "name": "CREB-regulated transcription coactivator 1", "aln": "MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQK---------SQYLQLGPSRGQYYGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPP-ADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQK---RVLLLTVPGMEETTSEADKNLSKQAWDTKKTGS-----------------------------------RPKSCEVPGINIFPSADQENTTALIPATHNTG-----GSLPDLTNIHFPSP-------------------------------------LPTPLDPEEPTFPALSSS---------------------SSTGNLAANLTHLGIGGAGQGMST--PGSSPQHRPAGVSPLSLSTEARRQ----QASPTLSPLSPITQAVAMDALSLEQQLP-------------------------YAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGID------------------IASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQ-------HTSTLGSVFGDAYYEQQMAARQANALSHQLEQF--NMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGS-LPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPD-MVLADPATEDTFRMDRL--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ99-1", "uniprot_id": "A0A8M3AQ99_DANRE", "id": "A0A8M3AQ99-1", "name": "", "aln": "MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSITRAARLQLQK---------TQYLQLGQNRGQYYGGSLPNVNQIGNTGVDLPFQTPFQNSGLDTSRTTRHHGLVDRVYRDRNRITSPHRRPLSVDKHGRQIDSCPYASVYLSPP-PDTSWRRTNSDSALHQSTLNPNPQDAFAGGSQDLQPK---QVLLLTMPGTGDPDSDMDKESQKQIWDQKKNTSQ----------------------------------RPKSNKIPGINIFPSPDQEITASLIPVAHNTG-----GSLPDLTNIQIPPP-------------------------------------LPTPLDPED-SSSSLSAS---------------------NSTGN--LANPHMGLTSAGQGVTSGQPTATVQRRHENVVPLILNTDSQQLPGLQQLSPTLSPPLSLAQAVTIDAMTLEQQLAQ------------------------YAFFSQPSTQT-------------------------------QGG-----------GGLPPLPVVSSSQT---------QTSVGID------------------INTAASLQQYRCRVGSSANQSPTSPVSNQGFSPGGSPQ-------HSSILGSVFGDAFYDQQLSPRQTSALSQQLEQF--NMMENPISSSSLFSEGSTLNYSQAAMLNLTGSHGN-LQDAQQLGYSSHGNIPNIILTG--------------------DVSFDADSQFPLDELKIDPLTLDGLHMLNDPD-MVLTDPATEDAFRMDRL--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QYY6-1", "uniprot_id": "F1QYY6_DANRE", "id": "F1QYY6-1", "name": "", "aln": "MASSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSITRAARLQLQK---------TQYLQLGQNRAQCYGGSLPNVNQIGNSNTDLPFQT----TVLDTNRTSRHHGLVDRVYRDRNRIASPHRRPLSVDKHGRQIDSCPYGSVYLSPP-PDTSWRRTNSDSALHQSAVNPAPQDSFVGGSQELQSKGVKTLLLLTPPDTEDAESEMEKDDSK--------TSL----------------------------------LTDSCDVPGINIFPSPDEEMNCSLMPGAHSTG-----GSLPDLTNIQFPPP-------------------------------------LPTPLDPDDPITFPTSSS---------------------SSTSNLTTNLTHLGISAASH-----VPPSPPAQHTGSAPSPSLSQQQTTPT----LPPAASPQIPLAQPITMDSLLLEQQLSQ------------------------YSLLSLLNDLQKQPHTLPQN---------------------------------IRLIRLPPLTVSSTPSTTQT------SLASQSP------------------TTTGGTANSYRSQPGSSTNQSPTSPVSNQGFSPGGSPQ-------HIQVVGSIFGDSFYDQQLPSRQTNSLSNQLEQFNMNMMENPGSTS----PCSTLNYTQAAMMGLTGSHNS-QQDAQQLSYSSHGNIPNIILTVTGESPPSLSKDLTSSLAGVGDVSFDADSQFPLDELKIDPLTLDGLHMLNDPD-MVLADPATEDTFRMDRL--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFU2-1", "uniprot_id": "M9PFU2_DROME", "id": "M9PFU2-1", "name": "", "aln": "---MANPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQEVSQSSPGAGNGTGGGGSGSGSGASGGGASPDGLGGGGGSPTAYRESRGRSVGVGPMR-RPSERKQDRSPYGSSSTQQTLDNGQLNPHLLGPPTAESLWRRSSSDSALHQSALVAGFNSDVNSMGANYQQQQHQQQQQPGQPRSHSPHHGINRTMSPQAQRRKSPLLQPHQLQLQQLQQQQQQMQHQHQLHQQLQMQQLQQHQQQHQQQQQQQNTPYNNAKFTNPVFRPLQDQVNFANTGSLPDLTALQNYGPQQQQQQSQQQPSQQQQQLQQTLSPVMSPHNHRRERDQSPSPFSPAGGGGGAGPGSPYQQQQHSPTGNTQQQQQQHQQPSNSPHLSFTNLATTQAAVTTFNPLPTLGPHNATDYRQPPNPPSPRSSPGLLSSVSATDLHSSAPASPIRQQQQAHQQQQQQQQAQQQQQQFDNSYNSLNTSFHNQFEIFSLGDSNSSPEQQGFANNFVALDFDDLSGG----GGGGPSGGGGSNGGGLTNGYNKPEMLDFSELSGSPEASGNNNHMRRGVSNLNNNGLSNGVVGSTHNGSTNLNGAGNNNSSSGGGTAQDPLGITTSPVPSPLGCPSSPLPIPIPMSAQSSPQQQHHHHQQQQQQHHQQQHHQQQQLSLSLHHSPHHSPMHSPHHGNSPLSSSSPVSHNACSNSNVVMNHQQQQQQHHHQQHHHQGSSQSHTPTTANIPSIIFSDYSSNADYTREIFDSLDLDLGQMDVAGLQMLSDQNPIMIADPNIEDSFRRDLNXYYEEAVAAIESGVLLEEDYQALLGSEALADEQVVTVEAAGAAAAVVTVEEAATVSEKDKKDLEVVELLVSGVMDDLVDSSDLDEEVRNFFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***********::***** ** **.:**:: *: . :: : * . . .: **. .. .. .. . : * :* :.: * * . .* * . .. : *. . *.** .:: ***:.********:: . . . . : : : * .. :: . . . : * : : . .:: :. ******: :: * *:*:.* . ..* .:. .::. :. * . . ..: . :..: : :** : ::: . * : . . *. : *.* . .:. ** ..*. . .* : .:.** :: . .* :*: .: ... :. .. :.:: :. ... .. :* * : . : : * :*.:. : : **:**.* : ::::** **:** * ", "identical_positions": 91, "similar_positions": 166, "identity": "10.14%" }, { "cls_id": "homologset.agr.MGI:2142527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54924-1", "uniprot_id": "EXOC8_RAT", "id": "O54924-1", "name": "Exocyst complex component 8", "aln": "----MSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRVQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLALLP---AAAAG----ASTGEDTAG-AGPRERGAAQAGFLPGPAGVPREGPGTGEEGKQRTLTTLLEKVEGCRDLLETPGQYLVYNGDLVEYEADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFP-ESRIFQAENAKIKREWLEVLEETKRALSDKRRREQEEAAALRAPPPVTS-KGSNPFEDEAEEELATPEAEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLE--DKPSPPSVKELRAKVDERVRQLTEVLVFELSP--DRSLRGGPKATRRAVSQLIRLG------QCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFETDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKES------LSTAAECVKVAKEHCQQLGEIGLDLTFIIHALLVKDIQGALLSYKE------------IIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMRSCGVSNFEQYTGDDCWVNLSYTVVAFTKQT------MGFLEEALKLYFPELHMVLLESLVEVILVAVQHVDYSLRCEQDPEKKTFIRQNASFLYDTVLP--VVERRFEEGVGKPAKQLQDLRNASRLLRVNPESTTSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGF7-1", "uniprot_id": "EXOC8_MOUSE", "id": "Q6PGF7-1", "name": "Exocyst complex component 8", "aln": "----MSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRVQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLALLP---AAAAG----ASAGEDTAG-AGPRERGAVQAGFLPGPAGVPREGSGTGEEGKQRTLTTLLEKVEGCRDLLETPGQYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFP-ESRIFQAENAKIKREWLEVLEETKRALSDKRRREQEEAAAPRAPPPVTS-KGSNPFEDEDDEELATPEAEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLE--DKPSPPPVKELRAKVDERVRQLTEVLVFELSP--DRSLRGGPKATRRAVSQLIRLG------QCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFETDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKES------LSTAAECVKVAKEHCQQLGEIGLDLTFIIHALLVKDIQGALHSYKE------------IIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSNFEQYTGDDCWVNLSYTVVAFTKQT------MGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDYSLRCEQDPEKKAFIRQNASFLYETVLP--VVERRFEEGVGKPAKQLQDLRNASRLLRVNPESTTSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYI6-1", "uniprot_id": "EXOC8_HUMAN", "id": "Q8IYI6-1", "name": "Exocyst complex component 8", "aln": "MAMAMSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLP---AAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLETPGQYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVNVKDNPPMKDMFKLLMFP-ESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRGPPQVTS-KATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLE--DKPSPPPVKELRAKVEERVRQLTEVLVFELSP--DRSLRGGPKATRRAVSQLIRLG------QCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFEIDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKES------LSTAAECVKVAKEHCQQLGDIGLDLTFIIHALLVKDIQGALHSYKE------------IIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSNFEQYTGDDCWVNLSYTVVAFTKQT------MGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDYSLRCEQDPEKKAFIRQNASFLYETVLP--VVEKRFEEGVGKPAKQLQDLRNASRLIRVNPESTTSVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38261-1", "uniprot_id": "EXO84_YEAST", "id": "P38261-1", "name": "Exocyst complex component EXO84", "aln": "----MVEFSLKKARNNWKHVKKSASSPAKQKTPPSPAKPKQKTKKNPYSDLKDPATSYTLPTINARERSRVATSMQR-RLSIHNTNYAPPTLDYSMPLPDMPNMIVPNDNVDSSHNNSSFTTENESVSSKGPSNSLNLSTADLSLNDSSYNKVPARSAMRNTVNPSGSNDPFNNSTSLRKMLANPHFNAKDFVHDKLGNASAIT-IDKFTSN----LTDLSIQVQEEVKLNINKSYNEIMTVNNDLNVAMLELKRVRANINDLNEVLDQCTKIAEKRLQLQDQIDQERQGNFNNVESHSNSPALLPPLKAGQNGNLMRRDRSSVLILEKFWDTELDQLFKNVEGAQKFINSTKGRHILMNSANWMELNTTTGKPLQMVQIFILNDLVLIADKSRDKQNDFIVSQCYPLKDVTVTQEEFSTKRLLFKFSNSNSSLYECRDADECSRLLDVIRKAKDDLCDIFHVEEENSKRIRESFRYLQSTQQTPGRENNRSPNKNKRRSMGGSITPGRNVTGAMDQYLLQNLTLSMHSRPRSRDMSSTAQRLKFLDEGVEEIDIELARLRFESAVETLLDIESQLEDLSERISDEELMLLNLISLKIEQRREAISSKLSQSILSSNEIVHLKSGTENMIKLGLPEQALDLFLQNRSNFIQDLILQIGSVDNPTNYLTQLAVIRFQTIKKTVEDFQDIFKELGAKISSILVDWCSDEVDNHFKLIDKQLLNDEMLSPGSIKSSRKQIDGLKAVGLDFVYKLDEFIKKNSDKIR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . .: *.: : .* .** : * .. . : ::: . * : ::. .: . *. : *: : *. . : : : . .* .:* ::* . :: : :: .. * : .:. :. . .. .. . : . : : .:.. * : .: . *:*. . .: : : :. * * :: * : : * . : : .** . * .* :: :: : . . : :** .: *:: :: .: . : .. :..: : * :.: : * :. : .. : : ::* :: :: : :: .:: : .:.: :: . : : . :::* .:: : .:.:* : * * :: :*:* : :: . . : :. *. :* * . :::* . *:: : : :: ..** : . .. . .. :. .*.. * : : : ::: * .* :*::*: :*. .* :::. * * . : **:. * . .* * :: ::*:: . .:::.: : :**. .. .: : : * * * : : * .:* : : * :: .: : . :..: . : .* .: * : .:* : :*. :: :: * * *: : : ..::: *.:. ", "identical_positions": 76, "similar_positions": 290, "identity": "9.92%" }, { "cls_id": "homologset.agr.MGI:2142534", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TB8-1", "uniprot_id": "VAT1L_MOUSE", "id": "Q80TB8-1", "name": "Putative NADPH-dependent quinone oxidoreductase VAT1L", "aln": "MAKEGVEKAEETEQMIEKETSKEPAEGG--DGSHRLGDAQEMRAVVLAGFGGLNKLRLSRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYTMLFEIANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRSGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R3N4-1", "uniprot_id": "M0R3N4_RAT", "id": "M0R3N4-1", "name": "NADPH:quinone reductase", "aln": "MAKEGVEKAEETEQMIEKETSKEPAEGG--DGSHRLGDAQEMRAVVLAGFGGLNKLRLSRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYTMLFEIANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRSGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HCJ6-1", "uniprot_id": "VAT1L_HUMAN", "id": "Q9HCJ6-1", "name": "Putative NADPH-dependent quinone oxidoreductase VAT1L", "aln": "MAKEGVEKAEETEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************:.******* **************************** **************************************************************************************************************.****:********************************************************************************************************************************************************:*******************************************************************************************", "identical_positions": 411, "similar_positions": 5, "identity": "98.09%" }, { "cls_id": "homologset.agr.MGI:2142538", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5XVC1-1", "uniprot_id": "A0A8I5XVC1_RAT", "id": "A0A8I5XVC1-1", "name": "", "aln": "MAWPPAQKPGDSKEEYGGPAQTDVCATQVSEEFPKSCTDEVLSSGSISFSGDLQSCSHTSESPPETETPTTSSEEQDELSELSVLQ-DENKLSEKWINHLKSKEIHSERYQSDLRHLPEIPKASAEELNALRSFCTKKVNSIHQREDSRGKKSNRPKRLQLKWIAETSEVDPFNCTIPDELLNRIYLENTRATLAYIGAITQHNSSQCPSCTSKRAELAQSDFLRRRKTLLQSLLLQEKIDEHLHTTDFLTRIGEAHQDFPRLSDDPRIIWKRLTEKMQKGSSGSGQACSKQV-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TTJ4-1", "uniprot_id": "CH048_MOUSE", "id": "Q3TTJ4-1", "name": "Uncharacterized protein C8orf48 homolog", "aln": "MGWPPAQKPEDSKEEHGGPAQTDVCATQVSEEFPGSCADEVLSSGSISFSGELQSYSHTSESPVETKTPTTSSEEQDEQSELSLLQKDENKLSEMWINHLKSKEIHSERSQPDRRLPPEIPKESAEELDALQSFCTKKVNLIHQRQDLRAKKSNRPKRLQLRWIAETSEVDAFNCTIPDELWNRIYLENTRATLAYIGAITQHISSQCPSCNSKRAELAQSDFLRRRKTLLQSLLLQEKIDEHLHTTDFLTRVGEAHQGFPRLSDDPRIIWKRLTEKMLKGSSGFGRAYSKQV-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LL4-1", "uniprot_id": "CH048_HUMAN", "id": "Q96LL4-1", "name": "Uncharacterized protein C8orf48", "aln": "MAICPELAQTD---------KSALANLSDETETLKNSTDEVQTSSSFSSSGGRQSSPLTSGSKLEREKQTPSLEQGDTQSELLDYKNYEKKLSKKWINYLKLKDSNFERHQPDTKLPTEITRVSDEELNALQSYCTMKINLIHRRGDSKKKTSSRHKKLHLGLDVEASERDAFSCTVPDELLNRIYFKNMRTTPKQEAAAKQHISYQCPYCNRKRAELALSAFLKQKKTLLESFLLQERIDEHLHTKDFLTRIGEAHQDFPRLSDDPRIIWKRLTEKSHIRYSGFERSETEQKLQRDGNSACHLPFSLPFLKRLTLIKPELVIVNDNV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * * :: :. . . * ..:*** :*.*:* ** ** . ** * * :. *.* *: * *** : *:***: ***:** *: : ** *.* : .**.: * ***:**:*:** *:* **:* * : *.*.* *:*:* .*:** *.*.**:**** ****::* *:* .* .** * *** *. ****** * **:::****:*:****:*******.*****:*****.****************** ** :: ::* ", "identical_positions": 144, "similar_positions": 63, "identity": "43.9%" }, { "cls_id": "homologset.agr.MGI:2142544", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LL84-1", "uniprot_id": "A0ABK0LL84_RAT", "id": "A0ABK0LL84-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEERKMRCKEKKVPGAPHN---------SFRNTG-------------KEEEPAHQIQAMDPRLSRPAVGATQGI--------------------------------------------------------GLQGDFLSKKPQSLPDQSAADRSGGNQRSILGAPQAQS----------------------------------------------------------------------------------------------------------EEPAFSEMENCLCPGSSHLNLTQGENDHRGGGLIGDP-----------------------------------------EPGRALPAGFSP-------------LLEMSSKLPEADPSGSSFP-------------------------RPADCLLARDLTWELLASG------------MAALPGTRDIEGRAVLLLCAHSPAWLHPKCNSHELLSLLFYLRGIP----------------------------------------RPEVQALGLTVLVDAR--------------------------ICPPSSALTWGLSQLQEASPGSVQQLLLVG-KMPEDMPVGLQAKQLASHQSLLTHIPNMELPTSLG------------GCLSYCHQAWLDFRMRLETLQQSCQVACALLQGVIDSMKAMRQPLESGEVGELLQQAQSLMQQVLESPQLSWLQSQGSLELAWLKQGMPQVALSP-----------------------DYRSAVDKADELYGQVDELLHRLTLKSNQRIRALELLQALEAQEGVLCQIEVWLQEVGWPGLEEPGEPSLDMLLQAQG---PFQELDLVAQEQVKQGEKLLQPLVGWEAAELGPTGKRFLALRSQLMEFSRALAQRRQRLADAEKLFQFFKQASTWTEEGQRVLTELEQETPEVVLQRLQLHWSKHPDLPPAHFRKMWALATGLGS----------EGIRQECRWAWAQCQDTWLALDQKRE------------AALKPQ-SMNSTATLYVRRAPAIPTIPPLRKSYSFDQNLGKHLGDASNRGHCAATVTDCHRPEARGGIRPRSS------PSVPLSGSSDFRSPNRLQLVLAEMVATEREYVRALDYTIQNYFPELDRSDVPQGLRGQRAHLFGNLEKLRDFHFHFFLRELEACTRHPPRVAHAFLRHRVQFGMYALYSKNKPRSDALMSNYGHTFFKEKQQALGDHLDLASYLLKPIQRMSKYALLLQELARACG--------GPAQELGALQAAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFTVRAGH--HKSCRRVFLFEELLLFSKPRRGP--AGVDIFTYKRSFKMADLGLTECCGESKLRFEIWFRRRKARDLFVLQASDVATKQAWTADISRLLWRQAVHNKEVRMAEMASMGVGNKAFWDIAPSEEAINDRNINYVLKRRDVRSRAS----------------------------------IAVAPFDYDNPYLGALASLPGDRASCSVLGSLNLHLYRDPALLGVHWS----------------------------------------LLPPNFPEEASLDTEVDLGSQPSLTPEDSEVSSQCPSASGSSGSDSSCVSGQTMGRGLEDLSCV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPS6-1", "uniprot_id": "F8VPS6_MOUSE", "id": "F8VPS6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGPLECGDVSPDSQGHVADGKRFAVCSFRNTR-------------KEEEPAHEIQAMDPRPSRPAAGATQGV--------------------------------------------------------GLQGDFLAKEPQSLPEQRAEDGPRGYQRSIIGAPPTQS----------------------------------------------------------------------------------------------------------EEPAFSELENLLCSGSSHLNLTQGDNDYRGEGLIGDP-----------------------------------------GPGRTLPAGCSP-------------LSETSPKLLEADPSGSSFP-------------------------KPADCLLARDLAWELLASG------------MAALPGTRDVEGRAVLLLCAHSPAWLHPKSNSHELLSLLFYLRGIP----------------------------------------RPEVQALGLTVLVDAR--------------------------VCSPSSSLTWGLSRLQEASPGSVQQVLLIG-KMPEDVPVGLQWKQLRSHQSLLTHIPNVELPTSLG------------GSLSYCHQGWLDFRMRLEALQQSCQVACALLQGVIDSMKALRPPMESGEVAQLLQQTQSLMQQVLDSPQLSWLQSQGSQELAWLKQGTPRVTLSP-----------------------DYRSAVDKADALYGQVDELLHQLALKSNQRIRALELLQALEAQEGVLRQIEVWLQEVGWPGVEEPGEPSLDTLLQAQG---PFQELDLVAQEQVTQGEKLLQPLVGLEAAELGSPGKRFLALRSQLTEFSRALAQRRQRLADAEKLFQFFKQASTWTEEGRRLLTELEQERPEVVLQRLQLHWTRHPDLPPAHFRKMWALATGLGS----------EGIRQECRCAWAQCQDTWLALDQKRE------------AALKPMPATNNTATLYVRRAPAVPTVPPLRKAYSFDRNLGRHLQDVSSRGHCAAIVTDCHRPEARGGVRPRSS------PPVPLSGSSDFRSPNRLQLVLAEMVATEREYVRALDYTIQNYFPELDRPDVPQGLRGQRAHLFGNLEKLRDFHYNFFLRELEACTRHPPRVAHAFLRHRVQFGMYALYSKNKPRSDALMTNYGHTFFKEKQQALGDHLDLASYLLKPIQHMSKYALLLQELARACG--------GPAQELGALQAAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFTVRAGR--HKACRRVFLFEELLLFSKPRRGP--AGVDIFTYKRSFKMADLGLTECCGESQLRFEIWFRRRKARDLFVLQASDVATKQAWTADISRLLWRQAVHNKEVRMAEMASMGVGSKAFWDIAPSEEAINDRNINYVLKRRDVRSRAS----------------------------------IAVAPFDCDNPYLGALGSLPGDRASGSVLGSLNLHLYRDPALMGGHWS----------------------------------------LYPPNFSEEASLD----LGSQPSLTPEDSEVSSQCPSASGSSDSDSSCVSGQTMGRGLEDLSCV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q58EX7-1", "uniprot_id": "PKHG4_HUMAN", "id": "Q58EX7-1", "name": "Puratrophin-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERPLENGDESPDSQGHATDWR-FAVCSFRDAW-------------EEEEPASQMHVKDPGPPRPPAGATQDE--------------------------------------------------------ELQGSPLSRKFQLPP---AADESGDAQRGTVESSSVLS----------------------------------------------------------------------------------------------------------EGPGPSGVESLLCPMSSHLSLAQGESDTPGVGLVGDP-----------------------------------------GPSRAMPSGLSPGALDSDPVGLGDPLSEIS-KLLEAAPSGSGLP-------------------------KPADCLLAQDLCWELLASG------------MATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIP----------------------------------------RPEVQALGLTVLVDAR--------------------------ICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQLPS-QSLLTHIPTAGLPTSLG------------GGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKAVPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSP-----------------------DYRTAMDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEAGEPSLDMLLQAQG---SFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTEFSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPDLPPAHFRKMWALATGLGS----------EAIRQECRWAWARCQDTWLALDQKLE------------ASLKLP-PVGSTASLCVSQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQAS------PTVPPPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGHTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACG--------GPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGR--HKSVRRIFLFEELLLFSKPRHGP--TGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS----------------------------------IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCP----------------------------------------LYP-SFPEEAALEAEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KU89-1", "uniprot_id": "Q7KU89_DROME", "id": "Q7KU89-1", "name": "", "aln": "MFQLRREVWSERLGVWVQRVLVIVLHLWHRSSMSFVRRRQEAFKWIRRRLARRQCHADTNIETGRAEAAVTGSGAGAELAEILVPSDTQIDVPGGGIPGGQIPSLESTDRDMKEARAAPIARDDEDQEAGDPEEHGEEEDEEPPEVEQLSANANYVCCRYPGTTSSSTSGAADTLNRSKSRVQKYLKKCKQRLTGQAKMPTSSSTTTTTITLIRNEPAPTTIAERESEQALAEQEEELLEVEDLTEGSNGSYTDALPIECSLSASIAEEQQQGVDELEPPKEEEVPLETELTEPSSTPPPQSNPEGIPAPERFRLTADVDATLARLIDSHLSHIYPVYWARTRAILIQQARERLVCGFDGSLVRFEQRFLCKFAQIAATLRTAHQIGESWLWHPGWPLATSNGALVLQLSDAEIAHALRPSELYLCIKLESTESDADCKPRLYAVWRSSRKEESVQSHCIDHENPGELPLSVLQLEMSTAAAALMASDCGELPQLLQNLLVSVERSIERVSLNELQMPMHHDRGEDSLDEANNNGCNNNLLGSPKCALRRSDLITKNKLFNSRYMLRRLTNRQDSMNSTSSGNSNVSDRSSSSSSSSSSSAGEELLTSHSEAKMRSNSVGNEASGASTSPALPLYCLGNSFPHIDSDEEASDSIGPGKHHSLETCETELLPSSSIAELPEKLLTSGVYLPGTRTLQGDPLVTVDAACVASAG--INCYEMATLLLYYSTIPERSSCPFTTPATPGTTATINGHKSTEQQQQQQQQQQQQKQQPAQQTFTILIAIEKSQHLCVIDLICQSLRLLAKQIGNCEILAVCPDSSLLQLCNGQQQQKLQQQQQQNNNSDHPEPSSPSPVDLVKFISVDQVTTSVAPSQLPAGLLPSVPALSTLPGISQRHHDATKWREFFAQLEAFQRQCSTAGGRLVSALSEIRAADLQGLP-TRRQLYGQHRALSRALMDS-QLHSLRKMGAGQLARLQDLARAITSAPGSPRMTSQPQSSSSSSSGAFLNVDAACKLRKVTLLFNEVDRAAQRLEQLTEQRRERLRQLTRQRALEDEISEVTSWMGSDGAENLQKFSQLHWDNESQLRTQEQEFEKYYFIAMKHLAKGRDLHAAALKVSVLSESANN-----LKSALDQFAQKLELAHERYDAAGRLLHLLTQHQRENAAREELQRLAEQLGATSLLEKHWPVMRKTHTLPVASSTPAAAAGKRVSYRCSSASRSSFEGGPSSSNCSCWRESRNLEDMDQMEEEEEEQDHDCDGGDGEEQQSKIADSGLGVCDNCERNPKLARICSCQSLNEKSHDELLEDECFDRPSKRYMDIMHSPMEANAHLQCHGSSLELPKLEELSCLDPKIQKTLLLIMREMIGTERDYVRSLYYVIENYIDELLREDIPQPLRGQRNVIFGNIEKIFEFHNSHFLGELERYERNPLKVGAAFLEMESKFYLYALYNKNKPKSDTLLSEYGSSFFKPKQMQLQDKLDLASYLLKPVQRMGKYALLLQQLVKACKGVEGAALQEIAADVEELQRAEEMVKFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQNEFLVWQGRGGKKTLRQVFLFEELVLFSKARRFPDHKNLDIYIYKNSIKTSDIGLTAHTGDSATKFEIWFRKRKPDDTWMLQCMSEDIKNAWTEEISKLLWKQAKRNREVRLAEMSSMGIGSKPCLDIRPSNNQISDRSIPLAQLNKTPKLRHSEPGKGSMRRPNSLISESSLSSGTSTTSGSSISGGSSSGHNDGGGRHSLHFGKLPGAHSASSTNCSATLELINETQALKLAKSPSGGGIKGADTAADGGNTSGNGNGNGNAFRSSKRNHKRSTTIVSQLSMESGIVSDMCVTPDQEQSAAESSRSSWSTSTTGASGASTTSASTVILRRYRSYAHAAESASPESGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : . . . :*** . : . :* . *. . .:. :: *.: * . : . . . * * . . :: : .. .* :.:.: . .*:*.* ..*: .:. *. : : .**:. . *.. . ***.*. . ***** ::* .:: : * . * .. *: **:* ** :* *:: : : :: *.*:* . *: * . . * :: :: * :.: * :. **:.* . : * :* :**:: :.*..* . * ..:..::* . :* * . * : :::* * *: *. :*: *:: :: :* * : *. *:..** ::* ::** . *. : .* *. : :: *: . * ::: .: * * : *:: :* ::: :*..: . .. . .. . *:: * :*:: * :* * :*:::: : ..: ** . :*:: : ** * * .. :. *. .... : : . . :** * . : .:. . * . : .. *::.: * : : : :. .. :. * : .. * : : * *:: **:.***:***:* *.::**: ** * *:** ***** :***:**: :** .** *** *:* :*. ***. . :* :****.****:**:*::.** :*** ** * *:**********:*:*.*******:*.:** : :: *: *:.:*:*************:::.****:****:*:**:** * *: :*: *::******:****.*: * .:* : **.*:* :*:*** *:* :******:**. * ::**. . *:*** :**:***:** :*:***:*** ***:*.*. ** **:: *.**.: . : : * * : . * .. : .*** :: *. * .*.* .:. : . .:. *:.: : : . :. :*. ** ..*::*:*.:.::..* : * . .. ", "identical_positions": 311, "similar_positions": 374, "identity": "16.26%" }, { "cls_id": "homologset.agr.MGI:2142567", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M3AXD6-1", "uniprot_id": "A0A8M3AXD6_DANRE", "id": "A0A8M3AXD6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDID--YYRSK-PLAEESNFQTTNYDAISIDECHYNVLRDDLESDARDFEAPTWSLAVDPQYLKNFSKDAVKRQDVIHELIQTEINHVRTLKIVLNVYIRELRNTLQMDETRLERLFPQVENLLEVHQFFLDNLKLRRLDSMEPGSSQNYCIHNLGDILITQFSGEIGSRLRYLYGMFCSRHTDAVNFYKDLMQNNKKFQNLIRKICQLSIVRRLGIPEIILLITQRITKYPVLFERVIKYTEDESEEQMDLIKGLDFLKDTIAQVNAHVDEAEKEARLRELSSKLEPKSQVKMTSGRVFRREDMLQGKRKLLHEGMLNWRVTNNKGKGDKHTDVIVLLLSDVLLLLLEKD--SRLTFASLDGKPAVISLLKLIVREAAHNE-KAMFLISASLDTPEMYEFHTSSAEERNTWTNKIWKAVECCPDVKE----EEPE------ELSKKIWEFQRKLCVHDASIEQHLTEKLKLFSSIAASVTGVSDTSTSERHPLRG-NAAEPLQGERLLTGALKDVENLQNLLVMCEQGPTPFT----SRATDLVLKKPHAVTGLENNTHMLPENG-FESSMESMGDRIQVAN-----TDLDPQLRELHLSENQELSADEN--------LSVHFPKAEFYSTVSQLSRKLYSLQSVVQQLESHIKVQHATIEELK-----SRPRG-NSLLEQEKHRNLHKQNEELANFQRLQNQRLQEQRQWEQERERQMLQAEAREKELREREMACSRQEEMLAGEKQELARCREEYQQDLERLRESMRSVEKEKEKLELQKKYKKNENVP---VVYPLENEQ-IQIPPPYP---ILN-----------------IVSPGFTERAPLVPPRRESITGSL-VKPEVPIHLISTTNQTLK-AGSVQQKIPTKLAAQPKG-KEKHSKHR----NSHQRTNSAAGIEVSHVVPIKVAGREGG-----SLKAIRSSSPHHLHPDLFTHP--DKLSSSVSSHSGNSS--RKHNHSHNSHTS-----STHSTHSGHRKTKDSPNAEDIFFF----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TGC8-1", "uniprot_id": "A0AB32TGC8_DANRE", "id": "A0AB32TGC8-1", "name": "", "aln": "MADPPLHNSWPSFSWMKRWSFKRASDCKPCTQVRIPVSAPSSSSSLSPASIPEDVFFSSSPEEKRNFLAESDECSSEEDLLDLCPSLRDSEYFRDLQLGSTEPPNTQPTALNAPNKSPTSLIPLLSTPESESDQDFTESDTQQLLQIDHTLISSMDRLIAVKTSESQDYPPSDQDEDSDMDTFPILVRSMSTSRRHSWECPVSPIDLGRRFSLDTAGIDSDGEREVQCLAKSSLLPSSSFSESSVEEATSAVESESPKTQRQQPSTPTKTIYSRSEILATDEKSQAERVSRILETSKQAAREAGEKHESEEGLQSGEGRSHVLMVQKVLQELKQYHGA-KRRNSSTDRKEVTGNFTWYEFLAHENDEEEEDRPERPERGTKVKRTLSSLRNRMTGSFNKDKGKNREKEQHKEKGREREKDREKELSERVKVRRRSVSGHQLVPGSFSSCATCTLCSKTLQRKHGLQCLNCAVNVHKSCKNLLPECKSKAKDSAQKTSNGAAQLNSQALRDPCTALTPIDGSSRLSRCSAGMTVPHKGPSAQPASSSNPSASQNSSSSGSITGEMDEID--AFRVRRPADDTVSLASTVPESLIVEDAHYATVRSELEALAQDFEVESWSLAVDQHFSKTHSKEAIKRQDVIYELIQTEIHHVRTLKIMLRVYARELREALQLDERRLDCLFPRLDSLLELHNHFLSRLRERRVESLQPGSERNYAINKLSDILISQFSGELGDRMKESYGDFCSRHTEAVNHYKEQLQSNKKFQNLMRKLSNLSIVRRLGVPECILLVTQRITKYPVLLERILHNTEAGTEEHEGLAQALGLIKDVIVQVDAQVSLYEKEARLREIASKMEPKSLGKIKDGRVFRKEDLSQGRRKLLFEGTVNWKAASG-----RLKDILALLLTDVLVLLQEKD--QRYVFSTVDNKPSVISLQKLIVREVAHEE-RAMFLICASSNEPEMYEIHTASKEDRNTWITHIRQAVESCPHTEERLFSEEEE------ARVARVREYQERLALKDAQITQSLAEKLQLFAELSECVAGLEDSGSRSRLLLRG-DTSDLQQGETLLKAAITEVENLQNLLTSRVRGTSAQTEGNQSPSLSLLPRRADTFGGYDSNSSALPKNGSIKKKGPGAGGRTRDRSQ---RASSDPQLKEVFTCQDHDELDEASSPASTNMWSSCKLPESELYERVLLLSQRLYSLQAIISQQDSHIELQRASILTAERERPGSRTRGTDVLLEQEKQRNLEKHREELANFQRLQSQHRQEQARWEREREKQRRLAEADQQRLKEREEECRRLETRLAEERLELERQRQTYQQDLERLRESTRAVEKEKERLEQQRKLKKHNTVPNTAALYTQELTQ-LSTSSSFNGEFLLGGAGEQTHPQKSLLRASLSASPADYPERPEVHSRRESSCNTLPAKTEVPIHLISTTNQLHK-QGSVQQQIPTKLAALSKG-KEKSGKGK----SSHR-TDSLASVDMKQMLPIKLSARDSDGGH-KTRRPISPHQPQHSHSDSLSPP--DAYSDAQSSLAPALP--KTHNQTSQQTLP-----YTVS---------DEAAKEDVIFF----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZLL3-1", "uniprot_id": "A0A8I5ZLL3_RAT", "id": "A0A8I5ZLL3-1", "name": "", "aln": "----------------------VGSEPKPYAQPLDSGTAASTTRGGHGPRKPENPDFFSTMEDEQADGFLRHLSESAEDLSLDLGALQGSEYLRDLGLGAPSDLH---------------------------------------------------------QSEVVMDPETP----RRESFHTSCEGASALPQRHSWERPRSCSERGRRLSLDAS--EVDEGACLPRTLASLALNLSGDGQKTWIQGCLPVSGTPAPSS-KEGNSPEKRLRSKSVPVSCEEISCLEPAS--GSDVCAPPVQGLEPPVLECLEKDHVEPDHVLIVQQVLQELRQYHGARQRARMSISPGGPHSNLTWFEFLS--ESEDGVCKNEKTDKSTRVKRSLSSLRSRVT----------------RQKEKGKNPAHLKDKIQDVPGKRECVNGHQLVRGTFSGHSSCPLCG-------------------------------------------KPLLSSASLKEHPRTALLSDGSSPAPSRNVGMTVSQKGGLQP-----TPSPAGSGVRLGPIAGDMDEADSVFLKLKQTADDSLSLTSSNAESVFIEDPYTASLRCEIESDAHEFEAESWSLSVDVAYAKKQKKEVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSVQAVSRLFPCADDLLDMHSHFLARLKERRQEFLEEDSDRNYVIQKIGDVLVQQFSGETGERMKEKYGVFCSGHKDAVGHYKLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYKDLSQALNLIKDIISQVDAKVSECEKDQRLKEIVAKMDSKSSGKLKNGRTFRKEDMLQ--RQLHLDSTLCWKSTSG-----RLKDVLAVLLTDVLLLLQEKD--QKYVFASVDSKPPVISLQKLIVREVANEE-KAMFLISASMQGPEMYEIYTSSKEDRNIWMAHIRRAVESCPDEEEGIFLEAEE-RRMAEARTMKLRDFQERLSLKDQLIAQSLLEKQQIYLEMAQ-LSGLDESAQCRGLFRGGGDPSETLRGEQILRSAMSEIEGIQSLICR-HVGSTSSQVE-EGGVSAGLPRRAETFGGYDS-VGSPNKGGSFKRKVYNSDPRPQDWQGPASSPDSMPCDTTTPSGCCEESPQAVEMPSAESSPCLPTVLESELVHRVQTLSQLLLSLQAVIAQQDSYVEMQRMAIQEREKQFRLQSTRG-NLLLEQERQRNFEKQREERAGVEKLQNQLRQEQQRWERERARQQQELELAGARLQEREGEARQLRQRLDQERTELERQRQAYQHDLERLREAQRAVDRERERLELLRRFKKQNTVPGALPPEVLAEAQPASHPLNFNGDGLEGHLAPAKAPGTQG-SMLHGTGPEYGER-AEVARWDSAPAESRPAKSDVPIQLLSATNQIQR-QTAVQQQIPTKLAASTKGGKDKNSKSR----GSQRWESSASFDLKQQPLFNKLMGKDENAS--RNRRSLSPVLPAAHGSAPAPDPCFPAPSPVPAATAPEAF--KSGGTSLPPASP-----APS-LPTTPPTITDEVGKEDVIFF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9R4-4", "uniprot_id": "ARHGI_MOUSE", "id": "Q6P9R4-4", "name": "Rho guanine nucleotide exchange factor 18", "aln": "----------------------MGSEPKPYAQPLDSAAAASTTKGSCGPRKPENPDFFSTVEDEQEDGFLRHLSESTEDFSLDMGALQGSEYLRDLGLGAPSDLH---------------------------------------------------------QSEVIMDPETHRQEARRESSHTSCEGASALPQRRSWERSRSCSGSCRRLSLDAS--TVDKGACLPRTLASLALNLSGNGQKIWTQGCLPVSGTPAPSS-KECSSPEKRLRSKSVPVSC-EISCMELAS--DSDVCTSPVQGLEPPVLECLEKDHVEPEHVLIVQQVLQELRQYHGARQRARMSTSPGGAHSNLTWFEFLS--ESEDGACKIEKPGKSTRVKRSLSSLRSRVT----------------RQKEKGKSPAHLKDKTQDLPGKRECVNGHQLMRGTFSGHSSCPLCG-------------------------------------------EPLLNSASLKEHPRTTLLSDGSSPAPSRNVGMTISQKGGLQP-----TPSPAGSGVRLGPIAGDMDEADSVFLKLKQTADDSLSLTSSNAESVFIEDPYIASLRCEIESDAHEFEAESWSLSVDLAYAKKQKKEVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSGQAVSRLFPCADDLLDMHSHFLARLKERRQEFLEEGSDRNYVIQKIGDVLVQQFSGETGERMKEKYAVFCSGHNDAVGQYKLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYKDLSQALSLIKDIISQVDAKVSEYEKDQRLKEIAAKTDQKSSGKLKNGLTFRKEDMLQQ-RQLHLEGALCWKSTSG-----RLKDVLAVLLTDVLLLLQEKD--QKYVFASVDSKPPVISLQKLIVREVANEE-KAMFLISASMQGPEMYEMYTSSKEDRNIWMAHIRRAVESCPDEEEDVFSEAEE-KKIAEARTMKLQEFQERLSLKDQLIAQSLLEKQQIYLEMAQ-LSGLEESAQNRGLFRGGGDPSETLRGEQILRSAMSEIEGIQSLICQRHLGSTSSQVE-EGSVSAGLPRRAETFGGYDS-VGSPSKGGSFKRKVSNSDLRPQDWQGPASSPDSRPCDNSAPSGCCEESPQAVEMPSTES---LPTVLELELVHRVQTLSQLLLSLQAVIAQQDSYVEMQRTAIQEREKQFRLQSTRG-NLLLEQERQRNFEKQREERAGVEKLQSQLRQEQQRWERERARQQQELELAGARLQEREGEARQMRQRLDQERTELERQRQAYQHDLERLREAQRAVDRERERLELLRRFKKQNTVPGALPPEVLAEAQPASHPPSFNGDGLEGHSAPAKAPGTQGSAMLHGTGPDNVER-PEVARWDSAPPESRPAKSDVPIQLLSATNQIQR-QTAVQQQIPTKLAASTKGGKEKGSKSR----GSQRWESSASFDLKQQLLLSKFIGKDESAS--RNRRSLSPVLPAAHGSAPASDPCFPAPSPAPAATPPEAF--KFGGTSLPPVSP-----ASS-LPTTPLATTDEVSKEDVIFF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSZ5-4", "uniprot_id": "ARHGI_HUMAN", "id": "Q6ZSZ5-4", "name": "Rho guanine nucleotide exchange factor 18", "aln": "------------------------------------------------------------MGDDQEDDFPRRLSESMEDLSLDLGALQGSEYLQDLGLGAPSHSQ---------------------------------------------------------PGETPDSRPTG-EEPGRDSLFSSLAGSQDLSRRRSWERSRSCSESWRRLSLDAS--AVDEEPCLPRTLASLALNLPGGGLKTWTQGCLSGGGTPAESPGKECDSPKKRGRSRSVPVSFYEIRSPEISP--GLEVPTPPVQGLEPPVLECMEKDHVEPDHVLIVQQVLQELRQYHGARQRACMSASPGGAHSNLTWFEFLS--ESEDGAGKNEKSDKSTSVKRRLSCLRSRVT----------------RQKEKGKSPAHLKDKGQDARERRECVNGHQLLQGTFSGPSSCPLCG-------------------------------------------KPFLSSASLKEHPRGTLLSDGS-PALSRNVGMTVSQKGGPQP-----TPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQFSSKAIGRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKEKYGVFCSGHNEAVSHYKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGKMDLKSSSKLKNGLTFRKEDMLQ--RQLHLEGMLCWKTTSG-----RLKDILAILLTDVLLLLQEKD--QKYVFASVDSKPPVISLQKLIVREVANEE-KAMFLISASLQGPEMYEIYTSSKEDRNAWMAHIQRAVESCPDEEEGPFSLPEEERKVVEARATRLRDFQERLSMKDQLIAQSLLEKQQIYLEMAE-MGGLEDLPQPRGLFRGG-DPSETLQGELILKSAMSEIEGIQSLICR-QLGSANGQAE-DGGSSTGPPRRAETFAGYDC-TNSPTKNGSFKKKVSSTDPRPRDWRGPPNSPDLKLSDSDIP-GSSEESPQVVEAPGTESDPRLPTVLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAIQEREKQFRLQSTRG-NLLLEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGARLQEREGEARQLRERLEQERAELERQRQAYQHDLERLREAQRAVERERERLELLRRLKKQNTAPGALPPDTLAEAQPPSHPPSFNGEGLEGPRVSMLPS---------GVGPEYAER-PEVARRDSAPTENRLAKSDVPIQLLSATNQFQR-QAAVQQQIPTKLAASTKGGKDKGGKSR----GSQRWESSASFDLKQQLLLNKLMGKDESTS--RNRRSLSPILPGRHSPAPPPDPGFPAPSPPPADSPSEGFSLKAGGTALLPGPP-----APSPLPATPLSAKEDASKEDVIFF----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PBE1-1", "uniprot_id": "M9PBE1_DROME", "id": "M9PBE1-1", "name": "", "aln": "-----------------------------------------------------MDNAGEDSDNDVVTDFLNSNCSESSEALVNGGSTNRGASIESQNYCIP-----------------------------------------------------------------VINAPVPGPARAPIAPPPASNPASNTINNNNMIPTINVTPHSPALASKYNNIFEDTLSQLQNIRETVVQMKNSSSPSQHMQDGSLANHGLLSAAILSTSLPDLTGTGTGPASGGSNYAMWSSTAPQQCQFLHTDRRKSWTAVDDGSGAGDCTNKSVSLSSLDSEEQETIRVTEQRRRSARN---STGGISTHSLNEAELARDFERIAAKRSLATEIISRIPLQKSIST----------------SSIIAKEDIKAIARHLTDSEDENQSLLRAHAKIEVYDTVEKRPKRG--------------------------------------------SIFFRKKKPKAKTKSLVGGQLSACDVCGAAITLAQIK------------EHHLECKVKKMGGGQDYYDGPDASTFSNPEDQ-PLIRSDLQFLNEAPIEAQDLGADPVLGIVLKEHDSWTPNVPRELLKTLKDLQIKRQEHIYEFIMTEKHHCQTLIVMQKVFVESLERHFPSLN--LNSMFPRLQQLTDLHTCFLRQLRLKQRE--------QHMVDSIADILLDFFSLEQAQCLRLAYGEFCANHRSALDQFKLCLTEP-SFAEWYKHCLQNPLLKKKGIPECILFVTQRLTKYPLLIEPLLKSARDNKLETDKLQHALNLVKSLLVDVDACVAEKELRERQLEIYGRVDAKSFAIYKNKPFRKTELGVESRRRLKFDGLATLMQGRA-----KTQLVLVVVLTDCLCFLSENSGHNKYSFFTPEHKAGVVPLQKLLIREKAGTESRGIYIISSNPDFPEMYELKVQTPKDKNTWIQTIRQAVLDCP--ATDIIEAEDLTAEEKLRIGVNKRETIEKMRQKDIEQALLLEEKLMLQFNLLKEQQPFGDVAGTNSSCSAANFLAAFGSYKDLVSADCDTAELWRRVLNTVQDISQLASTIYSAATGQPVPRTLSSVGEKQSEQYASPTLPKRAETFAGFDEKRGKLAS---KLVLTPRLQELEEKREPKSG-----------SSSVSEQPLENNYAVLQVTHHLQTLLCVISQQMTTINNLQLQL----------------ALYRESPRSSAYTHKDQLEELRNLQDKQQEEKTAWQRQLKQQQ-------EELAEMRAQQLQLQKQIKAEQEDVRQQREQLYKKMELLSSQGLLLSPSTP----LPPVSNNHPPPAALLDDSHETDNGLSGS---------------------------GTGSSTPSVGGTFDRRKEKWLSGSSSCKTPPVNLISANNAPKVNPTLVKQKLPMKLSSLSSSGTSSSRVDKSASFNSASPTPYISAGSVQQMFPLKLADRRTATPSNCTTTPTTGMVPQHSRTGSSPAIIQQATTTATPTQTPVARAESVAHYTRTPTSSRTGIARTAGIAVATGTAPRAKPEEEEIYFXRQFTPEVEI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : : . : : : : * :*: * *. . :***: ::*:: ** :* :** :: .*: . *.. : : :** :.* : * ** .*: :: : :: :..:.*:*: ** * .. :: *. **: * .*:. :* : . .* : :: : .:::: *: * **::***:****:*.* ::: :. . : * :.*.::*. : :*:* * * * *: .: : ** .. : * : *:* :. : ::.::*:* * :* *:. .: * : : *. *:.* **::** * * :.:::*.:. : *****: . : :::* * * :** ** . : .:: :* * ** : .: . : . : : :: . * : :: . . : :. : . . . : . * : ::: * .* .:: : : :: : : * .:. : . .:.:: ...**.: .*: *::: * .* * . : . : *: :: : *: :.:* * . :. . .::. * : . . ... . . *::*:*:.* *:*::* **:: ... ... : .* : .: . *. : . . * . . : . . : . . *: ::* ", "identical_positions": 126, "similar_positions": 267, "identity": "7.88%" }, { "cls_id": "homologset.agr.MGI:2142572", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IMY1-1", "uniprot_id": "MTUS1_RAT", "id": "Q6IMY1-1", "name": "Microtubule-associated tumor suppressor 1 homolog", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLSPKFSLSTIHVRLTAKGLLRNLRLPSGLRKNT--------------------------------------------------------------------------------------------------------------------------------------------VIFHTVEKGR-QKNPRSLCIQTQTAPDVLSTE-RTLELADYKTKCENQSGFILHLKQLLSCGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVSLRGELVAASSTCEKLEKARNDLQTAYEGFVQKLNQQHQTDQTELENRLKEFYTAECEKLQSIYIEEAEKYKTQLQEQFDNLNAAHETTKLEIEASHSEKVELLKKTYETSLSEIKKSHEMEKKLLENLLNEKQESLEKQINDLKSENDALNERLKSEEQKQLSREKANSKNPQVMYLEQELESLKAVLEIKNEKLHQQDLKLMKMEKLVDNNTTLVDKLTRFQQENEELKARMDRHMAISRQLSTEQAALQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPFQSPRNSGSFSSPSISPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HZI1-1", "uniprot_id": "MTUS1_MOUSE", "id": "Q5HZI1-1", "name": "Microtubule-associated tumor suppressor 1 homolog", "aln": "MNDDNSD-RTEDGSRYVFIRDKNSNPSEYYQTSLSAQCPSVSHGDWNSDNPDAMVVDYEMDPAVDSSESVSLSHQCVEELAYPEPSSDFMGKHEFTMYSELTCQSPALVNTGKPQDLHSNCDSLEAIQDEKFDPLKPCECRSDDDYACGDSPEVLELKQTYGMKVDTANYTFIARHDIEQGQPLHAPGGLQTTVR---DRNALSSCGRTPPHSSKMYVRGVNYNRENFENLQATPSKTLNTTFTVISDVLMQTDS--PDVGVQGQNSLGNVTKEYTDGTRRGLIGEKEIQAVTLVSDGMEVPNGSASQEFYCVSEDDPNSETHSHGPYAQQEMGQNLRGTLPNCHVDGECPVLVPAFEKSKTRVLGSECKVTVTEDPHIDSHDNDSDIQSSTEELTLRSVSGQ-RGSPYEMGWGENGGAICTDKAGCMSTPVEQPPNLSFRLEPAEV-KKYNNVENGPRDAKRAPNLKGEPTNMPKPNLGKSATKTNTTVGSKVRKTEIISYPTPNFKNIKAKVISRSVLQPKDTSIMKDTPSPQVTGGSSPSPGPSKHLTMMNKAPRSDFKASKKAEIPINKTHKQQFNKLITSQAAQVTTHSKNASLGVPRTTSATKSNQENVDKTGSPHAGSETGSVAAFFQKIKGILPVKMKSSECLEVTYVSHIDQISPEK-GEQDGEAPMEKQELGKQATNEIFESKSLLVGSAPKTSTTPGRSSSKPDSRSLRKTPGLKAKVGPTAACLRRKSESRTLGSDRALSPQRIRRVSGSG------------------------------------------------------GHAAINKYEEKPPKQAFQNGS-GPLYLKPLVPRAHSHLLKTSPKGPSRKSLFTAFNSVEKGR-QKNPRSLCIQTQTAPDVLSSE-RTLELAQYKTKCESQSGFILHLRQLLSRGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVSLRGELVAASSACEKLEKARADLQTAYQEFVQKLNQQHQTDRTELENRLKDLYTAECEKLQSIYIEEAEKYKTQLQEQFDNLNAAHETTKLEIEASHSEKVELLKKTYETSLSEIKKSHEMEKKSLEDLLNEKQESLEKQINDLKSENDALNERLKSEEQKQLSREKANSKNPQVMYLEQELESLKAVLEIKNEKLHQQDMKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAALQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPFQSPRNSGSFSSPSISPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULD2-1", "uniprot_id": "MTUS1_HUMAN", "id": "Q9ULD2-1", "name": "Microtubule-associated tumor suppressor 1", "aln": "MTDDNSDDKIEDELQTFFTSDKDGNTHAYNPKSPPTQNSSASSVNWNSANPDDMVVDYETDPAVVTGENISLSLQGVEVFGHEKSSSDFISKQVLDMHKDSICQCPALVGTEKPKYLQHSCHSLEAVEGQSVEPSLPFVWKPNDNLNCAGYCDALELNQTFDMTVDKVNCTFISHHAIGKSQSFHTAGSLPPTGRRSGSTSSLSYSTWTSSHSDKTHARETTYDRESFENPQVTPSEAQDMTYTAFSDVVMQSEVFVSDIGNQCACSSGKVTSEYTDGSQQRLVGEKETQALTPVSDGMEVPNDSALQEFFCLSHDESNSEPHSQSSYRHKEMGQNLRETVSYCLIDDECPLMVPAFDKSEAQVLNPEHKVTETEDTQMVSKGKDLGTQNHTSELILSSPPGQKVGSSFGLTWDANDMVISTDKTMCMSTPVLEPTKVTFSVSPIEATEKCKKVEKGNRGLKNIPDSKEAPVNLCKPSLGKSTIKTNTPIGCKVRKTEIISYPRPNFKNVKAKVMSRAVLQPKDAALSKVTPRPQQTSASSPSSVNSRQQTVLSRTPRSDLNADKKAEILINKTHKQQFNKLITSQAVHVTTHSKNASHRVPRTTSAVKSNQEDVDKASSSNSACETGSVSALFQKIKGILPVKMESAECLEMTYVPNIDRISPEKKGEKENGTSMEKQELKQEIMNETFEYGSLFLGSASKTTTTSGRNISKPDSCGLRQIAAPKAKVGPPVSCLRRNSDNRNPSADRAVSPQRIRRVSSSGKPTSLKTAQSSWVNLPRPLPKSKASLKSPALRRTGSTPSIASTHSELSTYSNNSGNAAVIKYEEKPPKPAFQNGSSGSFYLKPLVSRAHVHLMKTPPKGPSRKNLFTALNAVEKSR-QKNPRSLCIQPQTAPDALPPE-KTLELTQYKTKCENQSGFILQLKQLLACGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQ----QHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPLQSPRNSGSFPSPSISPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JMQ7-1", "uniprot_id": "MTS1A_DANRE", "id": "A0JMQ7-1", "name": "Microtubule-associated tumor suppressor 1 homolog A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFFISKLSLSNIHVRLTAKGLLRNLQLLSGCKLAVG---------------------------------------------------------------------------------------------------------------------------------------------FLAVDKNKSRTNSKNPQPPTNGQPDLVPPESKSRNVEYYKAQCEKKNQTIRQLENTLLSNNRRFEAVAVVIKHLYAEHDEVMKQRRDLSQELVTLREELVSSGHSCERLEQEKEDLRSAFDGVLQKVQEQHRLDLADLEERLKTFYSTEWEKVHQAYQEEADKCKAQMEQQLEEIRSKHEALKKELESSHIEEVDGLKQQFEESFKGFKQSHEKEMQNLNETLKESEETLSNQIQDLMTENDSLKEKLN-AEVKRRMELAEKTQDSHTLYLEQELESLKVVLDIKNKQIHEQDKKLMQIDKLMERNVKLDECLKKLQQENEDLKARMDRHAALSRQLSTEQAVLQESLQKESKVNKRLSMENEELLWKLHNGDLNSPRKISPSPSLNLQSPRTSGMFSSPPVSPR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . . :. * :* .*: .. : . : :*:*.: :.*.:. .: ** :..* :: :: **::**.:. * :*.: * .* :***::***:** :*::*.:**:: ******.** ***::. :**:**: : :*::.:: .:* **: : :: *:*** :*: * **::. * ***:* * *:::*::::.: **: * *:*:** *::: **: :* *:. :*:.** * : *:: *.*.:*:*.:**:** :***:*:*:*: * *: . : ::.: :**********.**:***:::*:** ***:::**::.*. * : *.::*****:******:* *:*********.*****:************************* **:: ..*.:: :****.** *.**.:***", "identical_positions": 190, "similar_positions": 159, "identity": "14.89%" }, { "cls_id": "homologset.agr.MGI:2142581", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K001-1", "uniprot_id": "A0A0G2K001_RAT", "id": "A0A0G2K001-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDAFDNNSDIVEDGGPTPFEATLQQGFQCPPATEDLP---PLTNGYPPSISLYETQTKYPPYSQYPNGSANGFGAVRN------FSPTDYYHSEIPNTRPHEILEKP----SPP-------------------------------------------------QPPPPPLLPPPPPPVPQ------------------TVIPKKTGSPEIKLKITKTIQNGRELFESSLCGD-LLNEVQASEHLKSKHESRKEKRKK-SSRHESSRSEERKSHKVPKLEPEGQNRPNE----------------------------RVDPAPEKPREEP------VLKEAVPVQPILSSVPTTETSTG--VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR----------EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALQMTREERVEQYTFIYIDKQP--------------EESPSQAKKSVTS-KAEVK-----KPRRPRSVGNSQPE-------------QTSAGEVASPQSSTDPRRQSQ-----RRHTSVEEDGPPPVKIAWRTAAARKSLPASITMHKGSLDLHKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISSPSQRNEKSTPSASPPEATSGSAGPVEKKQQRRSIRTRSESEKSTEVVSKKKIKKEQQVETSPQASLKTGLQKGASEISDSCKPLKKRSRASTDVETASCTYRDTSDSDSRGPSDGQVGFGKQVDSPSAAADADASDAQSVDSSLSRRGVGLSKKDTVCQVCENTGDSLVACEGECCRHFHPECLGLAAVPEGRFTCEECETGQHPCFSCKVSGKDVKRCSVSVCGKFYHEACVRKFPTAIFESKGFRCPQHCCSSCSMEK---DIHKASKGRMMKCLRCPIAYHFGDACVAAGSVSVSSHILICSNHS---KRSSHSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNRAELMKLPMIPSSS-ASKKRCEKGGRLLCCESCPASFHPECLSIDMP-EGCWNCNDCKAGKKLHYKQIVWVKLGNYR---WWPAETCSPRSVPLNIQGLKHGVGDFPVLFFGSHDYYWVHQGRVFPYVEGDT-NFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKTSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPGDENPCGLESECLNRMSQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGN-GRTVCHCGADNCSGFLGVRPKSACTSAADEKTKNAKLK-KRRRGKAEAKQIHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCDECGSAAISFCEFCPHSFCKAHEKGALVPSALEGRLCCSNHDPASPVSPEY-WSKMRCKWESQDG--GEEVKE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P2L6-1", "uniprot_id": "NSD3_MOUSE", "id": "Q6P2L6-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDAFDNHSDIVEDGGPTPFEATLQQGFQYPPTTEDLP---PLTNGYPPSISLYETQTKYPPYNQYPNGSANGFGAVRN------FSPTDYYHSEIPNTRPHEILEKP----SPP-------------------------------------------------QPPPP-------PSVPQ------------------TVIPKKTGSPEIKLKITKTIQNGRELFESSLCGD-LLNEVQASEHTKSKHESRKEKRKK-SNRHESSRSEERRSHKIPKLEPEGQNRPNE----------------------------RVDTAPEKPREEP------VLKEAIPVQPILSSVPTTETSTG--VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHSKINTRGAR----------EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERVEQYTFIYIDKQP--------------EEASSQAKKNVTS-KTEVK-----KPRRPRSVLNSQPE-------------QTNAGEVASSQSSTDLRRQSQ-----RRHTSLEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISSPSQRSEKPAQSASSPEATSGSAGPVEKKQQRRSIRTRSESEKSAEVVPKKKIKKEQ-VETAPQASLKTGLQKGASEISDSCKPLKKRSRASTDVETASCTYRDTSDSDSRGLSDGQVGFGKQVDSPSATADADASDAQSVDSSLSRRGVGTSKKDTVCQVCEKAGDCLVACEGECCRHFHVECLGLTAVPEGHFTCEECETGQHPCFSCKVSGKDVKRCSVSVCGKFYHEACVRKFPTAIFESKGFRCPQHCCSSCSMEK---DIHKASKGRMMRCLRCPVAYHVGDACVAAGSVSVSSHILICSNHS---KRSSQSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNRAELMKLPMIPSSS-ASKKRCEKGGRLLCCESCPASFHPECLSIDMP-EGCWNCNDCKAGKKLHYKQIVWVKLGNYRQVLWWPAEICSPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-HFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEMERTSRKPPPYKHIKANKVIGKVQVQVADLSEIPRCNCKPGDENPCGLESQCLNRMSQYECHPQVCPAGDRCQNQCFTKRLYPDAEVIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGN-GRTVCHCGADNCSGFLGVRPKSACTSAVDEKTKNAKLK-KRRKVKAEAKPIHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPHGKWECPWHRCDECGSVAVSFCEFCPHSFCKAHGKGALVPSALEGRLCCSSHDPASPVSPEY-WSKIRCKWESQDS--GEEVKE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZ95-1", "uniprot_id": "NSD3_HUMAN", "id": "Q9BZ95-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLP---PLTNGYPSSISVYETQTKYQSYNQYPNGSANGFGAVRN------FSPTDYYHSEIPNTRPHEILEKP----SPP-------------------------------------------------QPPPP-------PSVPQ------------------TVIPKKTGSPEIKLKITKTIQNGRELFESSLCGD-LLNEVQASEHTKSKHESRKEKRKK-SNKHDSSRSEERKSHKIPKLEPEEQNRPNE----------------------------RVDTVSEKPREEP------VLKEEAPVQPILSSVPTTEVSTG--VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR----------EYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQP--------------EEALSQAKKSVAS-KTEVK-----KTRRPRSVLNTQPE-------------QTNAGEVASSLSSTEIRRHSQ-----RRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQ-VETVPQATVKTGLQKGASEISDSCKPLKKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGECCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEK---DIHKASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHS---KRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAELMKLPMIPSSS-ASKKKCEKGGRLLCCESCPASFHPECLSIEMP-EGCWNCNDCKAGKKLHYKQIVWVKLGNYR---WWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGN-GRTECHCGADNCSGFLGVRPKSACASTNEEKAKNAKLKQKRRKIKTEPKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCDECSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMAPVSPEY-WSKIKCKWESQDH--GEEVKE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1N3-1", "uniprot_id": "A0A8M2B1N3_DANRE", "id": "A0A8M2B1N3-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDVYEAISDPGDDGGQQNFDSPLESGFSYP--AEDVP---VITNGYPTGVGTYEQQAKFALYSQFPNGSANGYGAIRN------YGDHSLLLGEGTVLRPPVVQEKPQTHISPPSHSHHHQQPHHPHHHHHQQQQQHHPHNPPLLPHHHHHHPPPASHLMPQVLPPPPPLLLPSSPPLLSPQESTISNPIGQPVNTIITTTPKKTSSPEIKLKIIKTYQNGRELFESSLCGD-LLQEFQAGEDSRRQHEQKKEKRKKRGSRHGAGQEESQQPSKVEEERSVVVHNPVQ----------------------------TTESQVAFREEQQPQSSLKSPKAELKEQKVEKHCPSVITSTGTSQEYEIGDLVWAKVGTYPWWPCMVSSDPQSNVHTRINTRGCK----------EYHVQFFGSVPERAWIHEKRTVVYKSENQFDELQAETLRKSTNPTEKQKLLKPQSQKERAQWEVGVGHAEAALQMTREERNENYTFIYIDKEPGADAETAAAPAPAPDSAPTAPTDTVTSPKATAKNRPERKQRRSRGSAGAKEEPIPRRQQPRRQCSMNSVGETSSPNQGEDAMEQEQPCSPPKPAPRPKEPSPPPVRTPWRTAAARKLLPLSITMKKLNVEIIKCDWQ---LPKQKVELPKKTESEERPSSRVKSPEGSSNKAEAETCSSEEERAASPSGWSDQEHTSAEQS---------TERKQQRRSVRSRSESEKSVEPVPKKKVKKEQ-AETAPQMDFKTGSQKGASEISDSCKPLKKRSRASTDVEMASSLYRDTSDSDSRGLNDPQTGFGKRSDSP-ATVDADGSDAQSVDSSLSRQGGSSSKKDTVCHVCETFGDSLVSCEGDCNRLFHPECMGSNSGKESETVCQECKTGSHPCFSCKVTEGDMKRCSVNGCGRYYHETCVRKYTGSASDTKGLRCPQHSCATCCLDR---DLQKAGKGRMMRCIRCPVAYHTGDGCVAAGSVLITPHIIICSNHSSSRKNGHFSSPVNVGWCFICARGLLVHDHTDTILSSYTFKSHYLLTESNRAELMKLPMIPSSSSATKKNIGKGGRLLCCEACPASFHPECLKIEMP-EGTWLCGECKSGKKPHYKQIVWVKLGNYR---WWPAEICNPRLVPSNIQSLKHDIGDFPVFFFGSHDYYWINQGRVFPYVESDK-NFAEGQVGINKTFKKALEEAAKRFQELKAQRETKEALEQERNSRRPPPYKLIKSNKPFGKVQLHVADLSEIPRCNCKPTDERPCSQDSQCLNRMLQYECHPQVCPAGDRCHNQCFSKRLYPDTEVIKTTGRGWGLKTKQDLKKGDFVMEYVGELIDSEECKQRIRTANENHVTNFYMLTLTKDRVIDAGPKGNLSRFMNHSCSPNCETQKWTVNGDVRIGLFTLCDISADTELTFNYNLDCLGN-GRTSCHCGSENCSGFLGVKPKSAVVMEREEKVRNAKLKPKKRKLKTESKQTHELYCYCCGEGGELVMCDKKDCPKAYHLLCLNLSKPPYGRWECPWHQCSVCQRTATSFCHFCPASFCREHERGQLAVSALDKQPCCSNHDPKRPLGPQANRSQVTVKKEPLDGNANEEEEEEEEETGDGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MT36-1", "uniprot_id": "NSD_DROME", "id": "Q8MT36-1", "name": "Nuclear receptor binding SET domain protein", "aln": "MKLSTDAHSEIEGDAAHGNVLCNSASDSLTATDEVAAGNDESVATEGDDVEIPRDTNNSTPVRLLDKPGQNPVQNGAQPAAEESELESQRQTPVQKQQQQRVSMVNRKRDLINLQSALSPKYIGYANANSPTPLSDSDDTIRTTRRRVNQAAALNNSSAGETLAHDNASPRTPGGGGGGGGDDSANQLLSKTYMSPIEKLLIKNGASSPNSTGFEAGSEDLGIRPIVRKHVKRKMKRVPKAKVTLELDEKNQQEVDEKSVKTEPIDEEVDRTDEAPTQEAQTTAISIKSETEAEHKAAVDVHIKQEDTIRLDIVNNPVESTSIVITEEPKDLEKSTEELAFALPLASSTEVDLKSPPDLSSTALATSIKSPSSVSIDSAKGLSIVTDPG-WPTYQVGDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKR-TKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTYENVVT-------------LNRQKRKRTKYMMQDTSDVG------SSLYDSTDNLHNK-------------QGTQLLAVKRERSESPFSPAFSPVKSKNEKRAKRRKLSNGTEADTGSNSMAVTPSQTETTVDSSAYENPEFRQLLSAVMEYVMMNRS-DEKVEKVLLSVVSNIWSLKQIQLRELERDLASG-----EIEEPLGSSVVGRGSGVGTIKRLSNRLMTMMVRRSMTPVVTPSTTPAPSEPDRRLSEPPKTKKPVNRPIEEVIEDILQLDSKYLFRGLSREPICKYCYQAGSDLVRCSRTCSSWLHADCLERKVTGAPMPKIGSRKALVIPPTSKSPSPDEDHVTADAKEVVAVGTSLVCHECNVGEPEGCVICHQVESPAVPSTPRKEDSSSHTPIEDKLLTCSQPMCGKRFHTSCCKYWPQASSSKHSARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHN----IAKADAHVNVLWCYICVK--------------------------------------------------GGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLPLYGEIVWAKFNNFR---WWPAIILPPTEVPSNILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVPPLRFSQN-LEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWDDLMNNSKKACFCGAKRCSGEIGGKLKDDAVKAHAKLKQMRRAKASAVRIHVKPKKTPKVKHISADDEP----MDAKDE------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:* . . * *:: : .::: : * .* : . : . . * * * : ** .. * ::: * : . . :. . . * : :. :. * .. . . * . *: *:.: :* :*: *.*: : : :*.: :. :. . . * .. . : : . :.* : .: : * . : ...* :::***.*.** :* :*****..** :: .: :: : : **:**.. .* *:: :. : . : :::: * : : * : *: : . * .: .*: ::. .:* *:: * : . : .. : . .: . . . : : . . . . . : :. . . : : * . . : : : : : . : . : .. . : . :. : : . :: .:* .* ... ... .* . *. :: .*: :. *..: . . . * :.** . .: : ...* .. * .: : .. * .: : . * . * * : . . . . .. . * . .: ** **: :* :* : :. : ..:. ***:* * :* : .::: ...:: :*:*** :** . *:.**: :.. :**..*. . .: :** :*::*.: **.*:***:** :.*..* .* : : : * :*::*: * :***.*:.*:* **** * ** ** *. .** * ***:**: *: : **: *:*.*. : : : :.:...:***:: : :**:*: :: . . .. :**** **:** . ::. *.::. *** * **.**. :: ***** **:*: * **. *.*: * :* * *:: **:** .:. : *:** *****:*: * : *:. :.: *:*:* : ** :******** :*******.*********** *:*:*:: **... ****** * * * .:. *.**:..*** :* : *. . : : : * . : :.:.* : ..: * ** ", "identical_positions": 258, "similar_positions": 403, "identity": "15.76%" }, { "cls_id": "homologset.agr.MGI:2142593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A243-1", "uniprot_id": "D4A243_RAT", "id": "D4A243-1", "name": "", "aln": "MPKSPQGSLQPGLTLLLPHSGLLAASWPLLRPWQESMHPSTVAQRRPQAQSRAGPVLSVGRGDRLRGKDPVATRDLDSLLIWNYKPQKAFRLSHLTPDLRKPFVAKQQQLLPTCYSWRATGPDAQLQGYGRIMCEGPSRISGPIPPDPTLCPDYYRRPASAQGRLEGNA------LKLDLLTSGRDLDS------SPPRGPRIRPGAREILERGQRGVGDVLLQLGGISLGSGVSPKRKDPKDHEKENLRRIKEIQRRFQDQERSREQAQPKPLKALWRSPKYDSVESRVKARMKELGPASVTEPAQFLRAHSRCGPG-LPPSRASSPQLTLPG---SKAKGPGLGVDFISHNARAAKRAPRRHSRSLQVLAQVLEQQRQAQEHYNATQKGHVPHYLLERRDLWRKEAEARKRSQPDPSMPPGHTLMPENQRLETLNNLLQSQSKLLRELVLLPAGADSLRAQGYRAELDRKLVQIEEAIKIFSRPKVFVKMDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSV9-1", "uniprot_id": "ENKD1_MOUSE", "id": "Q7TSV9-1", "name": "Enkurin domain-containing protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MCEGPSRISGPIPPDPTLCPDYYRRPASAQGRLEGNA------LKLDLLTSGRDLDS------SPPRGPRIRPEAREILERGQRGVGDVLLQLGCISLGSGVSPKRKNPKDHEKENLRRIKEIQRRFQDQERSREQGQPKPLKALWRSPKYDNVESRVKARMKELGPTSVTEPAHFLRAHSRCGPG-LPPSRASSPQLALPG---PQAKGPGLGVDFISRNALAAKRAPRRHSRSLQVLAQVQEQQRQAQERYNATQKGHVPHYLLERRDLWRKEAEARQRSQPDPSMPPGHTLMPENQRLETLNNLLQSQSQLLRELVLLPAGADSLRAQGHRAELDRKLVQIEEAIKIFSRPKVFVKMDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0I2-1", "uniprot_id": "ENKD1_HUMAN", "id": "Q9H0I2-1", "name": "Enkurin domain-containing protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MCEGPSRISGPIPPDPTLCPDNYRRPTSAQGRLEGNA------LKLDLLTSDRALDT------TAPRGPCIGPGAGEILERGQRGVGDVLLQLEGISLGPGASLKRKDPKDHEKENLRRIREIQKRFREQERSREQGQPRPLKALWRSPKYDKVESRVKAQLQEPGPASGTESAHFLRAHSRCGPG-LPPPHVSSPQPTPPG---PEAKEPGLGVDFIRHNARAAKRAPRRHSCSLQVLAQVLEQQRQAQEHYNATQKGHVPHYLLERRDLWRREAEARKQSQPDPAMPPGHTRMPENQRLETLTKLLQSQSQLLRELVLLPAGADSLRAQSHRAELDRKLVQVEEAIKIFSRPKVFVKMDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDT0-1", "uniprot_id": "A0A8M9QDT0_DANRE", "id": "A0A8M9QDT0-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------MCEGPSAISGPIPPDPTLFPEYYRRPSSARGRLEGNAPNGSSPLLKGPLAPDPALHPGCYSARSSPR-PRIGANAAHILERGQRGVVGNLLRLDGVALSPSPAKPKPAIRDFGKENVRKLREVQRRFRELEAQREHAKPVPVKALWISPKYQDVPSRVMAQLQETSPLKKPEYQNFLKAHSVCGAGGRPVLRRSDSGPTAAGDSDSEMHVRGHTVDFVSHNARAAAKTSMRRSQSLQNLQDKTP---------ACAVKGKVPPYLEQRKAQWRKEEEEKKRNTPDPSVPAGHTQMSERERQETLHSLKETHRSLVSELLSLPVKADTLSIRSRRADLDQRLSEVEEAIKIFSRDKVYVKVDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****** *********** *: ****:**:******* * . *:.. *.. :.** * * . * .********* . **:* ::*... : : :*. ***:*:::*:*:**:: * .**:.:* *:**** ****:.* *** *:::* .* . .* :**:*** **.* * : *.. : .* .: : * ***: :** ** ::. *:* *** * : .: **:** ** :*: **:* * :::. ***::*.*** *.*.:* *** .* ::: .*: **: **. **:* :. **:**::* ::********* **:**:* ", "identical_positions": 159, "similar_positions": 97, "identity": "32.19%" }, { "cls_id": "homologset.agr.MGI:2142598", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGK6-1", "uniprot_id": "YLAT2_MOUSE", "id": "Q8BGK6-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEAQELGSPTPT---YHLLPKANQHTVKEDAGSPSQGSPE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLS-LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQG-----HTEHFQDAFKGSSWNVGD--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSMIHIERFTPVPALLFN-----CTMTLIYLVVKDVFLLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----DWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDT------------INSLIGIGIALSGVPVYFLGVYLPESR--RPLFIRNVLATVTRVTQKLCFCVLTELDVTEEKNVERKTD--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMM8-1", "uniprot_id": "YLAT2_RAT", "id": "D3ZMM8-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEARELGSPTPT---YHLLPKANQHTVKEDASSPSQGSPE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLS-LVVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQG-----HTEHFQDAFKGSSWNVGD--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSMIHIERFTPVPALLFN-----CTMTLIYLVVKDVFLLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----DWPRPLKLSLFFPIVFCICSLFLVAVPLFSDT------------INSLIGIGIALSGVPVYFMGVYLPEAR--RPLFIRKVLATVTRVTQKLCFCVLTELDVAEEKNVERKTD--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92536-1", "uniprot_id": "YLAT2_HUMAN", "id": "Q92536-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEAREPGRPTPT---YHLVPNTSQSQVEEDVSSPPQRSSE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMS-LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQG-----HSEHFQDAFEGSSWDMGN--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFN-----CTMALIYLIVEDVFQLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDT------------INSLIGIGIALSGVPFYFMGVYLPESR--RPLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59I64-1", "uniprot_id": "YLAT2_DANRE", "id": "Q59I64-1", "name": "Y+L amino acid transporter 2", "aln": "--------------------------------------------------------MQLK---KEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSASYGLS-LVIWAIGGIFSVVGALCYAELGTTITKSGASYAYILESFGGFIAFIRLWTSLLIIEPTSQAVIAITFANYLVQPLFPTCEPPYSASRLIAAACICLLTFINSAYVKWGTRVQDVFTYAKVLALIVIIITGIVKLCQG-----FTINFEDSFQGSSRDPGG--IALALYSALFSYSGWDTLNFVTEEIKNPERNLPLSIAISMPIVTIIYILTNVAYYAVLDMSAILAS-DAVAVTFADHTLG--VMSWTIPIAVALSCYGGLNSSIIAASRLFFVGAREGHLPDALSMIHIERFTPVPALLFN-----CAMALIYLTVEDVFQLIN-YYSFSYWFFVGLSIAGQIYLRWKEP----DRPRPLKLSLVYPIIFCLCVVFLVAVPLYSDT------------LNTLIGIAIALSGVPVYFLGIHLPESK--RPPIITKLLSAITRFTQFTCFYVLTEMDTVD-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHK8-1", "uniprot_id": "A0A0B4KHK8_DROME", "id": "A0A0B4KHK8-1", "name": "Y+L amino acid transporter 2", "aln": "-------------METESLNRKNSSRK-SSIVNGNGDASAKLTNGDGDGGGDGGGEVTLK---AKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLA-LIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLG-----NTQYFT--FENTDTKVTS--IALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGS-SAVAVTYAERAFG--MLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAM-----ALLSMLYLTVSDIFALIN-YVGFATWLSIGVAVLCLPWLRWAQP----NLPRPIRVPMVFPIVYLIATIFVTVVPMYASP------------VETGYGILMILSSIPVYLV--FIAWKN--KPIWFQKTMVSLTRFLQKMLMVLGKQTKPAQV----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "-----MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCGSVGLA-LIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADTEVTKWNQ--RGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNFRNAFEGTETATAYG-IVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQH-FIVCTVTILAPPPGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQG-RHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFG---VTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLN--------RVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.::. :. . ::*:*:*. .. : .. : : :*.... ::. * : *:*: *.*.*. :: * :* . :: . .: . : :. . : . ::: *: . :*: : *: :. : * * : : .. : :: * ::.: *:. :: *:*:* :.* : * : : * : *::: :: . : : :. :* . :.:* . : : : .*: .:* :* : * . : :: : : : .: : : . . :: . ::: .* . . : : . : . : ", "identical_positions": 33, "similar_positions": 140, "identity": "5.64%" }, { "cls_id": "homologset.agr.MGI:2142610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJR7-1", "uniprot_id": "A0ABK0LJR7_RAT", "id": "A0ABK0LJR7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MDRALKDVFDYSYRDYILSWYGNLSRD-DGQLYHLLLDDFWDIAKQIRYRLSHVDVVKVVCNDIVKALLTHFCDLKAATARHEEQ-------------------PRPFVLHACLKDS-----HDEVRFLQTCSQVLVFCLLPSKDIQSLSLRTMLAEILTTKVLKPVVELLSNPDYINQMLLAQ-LEYREQMSGHHKRAYTYAPSYEEFIKLINSNSD-------------------------VEFLKQLRYQIVVEIIQATTISSFPQLKRHK--GKESAAMKTDLLRARNMKRYINQLTVAKKQCEKRIRILGGPAYDQQEDGVSDEGEGPQSQKILQFEDIMTNPFYRERFGTYMERIDKR---ALVGFWESVEHLKNANKNEIPQLVSEMYQNFFVESK-EIPVEKSLYKEIQQCLVGNK------------------------GIEVFSKIQGDVYDVLRDRYYPSFLVS---------------DLYEKLIHEEEEETPDSQLASGKDELGS---------GGEAGEEVVEG-TSGVS-------------------------------DPASFAVIKLRELSEKLEYKR--------------------------QALSSIQNAPKPDKKIISKLKDEILVIEKECTDLQLHMARTDWWCEHLGLWKASITSAEVTEENGEQMPCYFVRVNLQEVGGVETKN----------------------WTVPRRLSEFQNLHRKLSECVPSLK-----KVQLPSLSKLPFKSIDHKFLEKSKNQLNKFLQNLLSDERLFQSEALYAFLS-PSPDYLKVIDVQGKKTSFSLSSFLEKLPRDFFSHQEEE------IEEDSDLSDYGDDVDG-----------KKDALAEPCFMLIGEIFELRGMFKWVR-RTLIALVQVTFGRTINKQIRDTVNWIFSEQMVVYYISAFRDAFWPNGKLAP------PTRIRSEAQSQETKQRAQQKLLENIPDTLQSLVGQQNARHGIIKIFKALQETRANKHLLYVLMELLLTELCPELR---------AHLDQLKAGQV---------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3ZT31-1", "uniprot_id": "SNX25_MOUSE", "id": "Q3ZT31-1", "name": "Sorting nexin-25", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MDRVLRDVFDYSYRDYILSWYGNLSRD-DGQLYHLLLDDFWEIVKQIRQRLSHVDVVKVVCNDIVKALLTHFCDLKAATARHEEQ-------------------PRPFVLHACLKDS-----HDEVRFLQTCSQVLVLCLLPSKDIQSLSLRTMLAEILTTKVLKPVVELLSNPDYINQMLLRQ-LEYREQMSEHHKRAYTYAPSYEDFIKLINSNSD-------------------------VDFLKQLRYQIVVEIIQATTISSFPQLKRHK--GKESAAMKTDLLRARNMKRYINQLTVAKKQCEKRIRILGGPAYDQQEDGASDEGEGPQSQKILQFEDIMTNPFYRERFGTYMERIDKR---ALVGFWESAEHLKNANKSEIPQLVSEMYQNFFVESK-EISVEKSLYKEIQQCLVGNR------------------------GIEVFSKIQADVSEVLRERYYPSFLVS---------------DLYEKLMREEEEEEPDAQLASEKDELGS---------GGEAGEEAVEG-TSGVS-------------------------------DPASFAVIKLRELNEKLEYKR--------------------------QALSSIQNAPKPDKKIISKLKDEILLIEKECTALQLHMARTDWWCENLGLWRASITSAEVTEENGEQMPCYFVRVNLQEVGGVETKN----------------------WTVPRRLSEFQNLHRKLSECVPSLK-----KVQLPSLSKLPFKSIDHKFLGKSRNQLNAFLQNLLSDERLFQSEALYAFLS-PSPDYLKVIDVQGKKTSFSLSSFLEKLPRDFFSHQEEE------IEEDSDLSDYGDDVDG-----------KKDSLAEPCFMLIGEIFELRGMFKWVR-RTLIALVQVTFGRTINKQIRDTVSWISSEQMLVYYISAFRDAFWPNGKLAP------PTRIRSVAQSQETKQRAQQKLLENIPDTLQSLVGQQNARHGIIKIFKALQETKANKHLLYVLMELLLTELCPELR---------AHLDQFKAGQV---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3E2-1", "uniprot_id": "SNX25_HUMAN", "id": "Q9H3E2-1", "name": "Sorting nexin-25", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MDKALKEVFDYSYRDYILSWYGNLSRD-EGQLYHLLLEDFWEIARQLHHRLSHVDVVKVVCNDVVRTLLTHFCDLKAANARHEEQ-------------------PRPFVLHACLRNS-----DDEVRFLQTCSRVLVFCLLPSKDVQSLSLRIMLAEILTTKVLKPVVELLSNPDYINQMLLAQ-LAYREQMNEHHKRAYTYAPSYEDFIKLINSNSD-------------------------VEFLKQLRYQIVVEIIQATTISSFPQLKRHK--GKETAAMKADLLRARNMKRYINQLTVAKKQCEKRIRILGGPAYDQQEDGALDEGEGPQSQKILQFEDILANTFYREHFGMYMERMDKR---ALISFWESVEHLKNANKNEIPQLVGEIYQNFFVESK-EISVEKSLYKEIQQCLVGNK------------------------GIEVFYKIQEDVYETLKDRYYPSFIVS---------------DLYEKLLIKEEEK-HASQMISNKDEMGP---------RDEAGEEAVDDGTNQIN-------------------------------EQASFAVNKLRELNEKLEYKR--------------------------QALNSIQNAPKPDKKIVSKLKDEIILIEKERTDLQLHMARTDWWCENLGMWKASITSGEVTEENGEQLPCYFVMVSLQEVGGVETKN----------------------WTVPRRLSEFQNLHRKLSECVPSLK-----KVQLPSLSKLPFKSIDQKFMEKSKNQLNKFLQNLLSDERLCQSEALYAFLS-PSPDYLKVIDVQGKKNSFSLSSFLERLPRDFFSHQEEE------TEEDSDLSDYGDDVDG-----------RKDALAEPCFMLIGEIFELRGMFKWVR-RTLIALVQVTFGRTINKQIRDTVSWIFSEQMLVYYINIFRDAFWPNGKLAP------PTTIRSKEQSQETKQRAQQKLLENIPDMLQSLVGQQNARHGIIKIFNALQETRANKHLLYALMELLLIELCPELR---------VHLDQLKAGQV---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3N0-1", "uniprot_id": "Q9W3N0_DROME", "id": "Q9W3N0-1", "name": "", "aln": "MESEEHAVDAMENRRLPLFPIEPEPSVTATQRLTLLATRLLRALQLNWRIIVSGITLTLLAVIWYYPTFFLFFAFVVYSLVLVFAAVAGTVYIHYIFTTNEPTPPSRVPSRLLYNATKSNIFDLPKPIKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTK-PKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETN-----------------TPPVFSTNSYLADE-----EKEMEFLRKLCEIMVILLLP-RGYSLPPLKVLLSEILSYKIFFPMIKMLTAPDYINQKVVQN-IETRLAAAAMSKRSYEYAASFEDFLKIINNSGN-------------------------LEELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFG-------------WNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKAS---ALIGFYLAVEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQIDKHERKLIETFLLGDA------------------------EPDIFYDIQRNVLRTLEEKYYPPFVLS---------------DQYRQLKEALDSNEIADPTLLMCHTIGD---------VQEPLADEQPGAADGLNGGAGGAIDVA---------------------AHTSYARRKLEQIQERIDKKN--------------------------QALDALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPVQPTSSKNGDSGHAN-LRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLK-----AIDLPTNFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLS-PSSDHLKQSLPSPKKSKFSLSTLFRSDAGKAHEASKATDPFWGLQRDDEDISTYLDGESGGEAKMLAADLDSKDSIAEPMYALMGEIFDMGGVFKWLR-KSLISFVQITYGRTINRQIRESVAYLFEESMLHNYFSAILKSFWPGGVLAS------AYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIRQLRVSNSNGTKLNTATAGAAAASAAAALVAATASASLPSLNHSGGGHSASTGGHQNHQGSSSASGSSAGASGATGGGAASHHQSHYHHGSHHHQQQQHHHSQAGSSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01846-1", "uniprot_id": "MDM1_YEAST", "id": "Q01846-1", "name": "Structural protein MDM1", "aln": "---------------------------------------------------MPKFPQFRLILVLFYLISMIQWSVITFSLGFFLN---VCIFAYFVFFKSLPDLPKPQPRFVDIVPESSNTVDVDKELKSVEGLIQDGNAQIGKELESIVNLIIKDFVQPWFTKIDKNSDAEFLKVIKWRLLQTLLVVKDKLMKNDSASLIVLKLLPIFNKHFSTFCDAREAVLSDLTLERHKSANIDLQIAVEFNKNYKIHKSLSLKPNALQKEIEKSIRKTVIGLLPHLFDNDELDSLLVFTLMTEVLTTCIISPLIFKFTDPDSWNLRIVSLSQNYFEEKHKVHKIRRMLSKELQDHRKVMNDVANKDVGEPSSEKLELNAEYTGKQFEHYLNQLDSLLDLSDIKYVAYSLALKIYQLKENEHLTKENLKYKKRLLLSLNLIESKLSFPGSEIDTASKKLAREANYPDLNMDNGIVLKEMASFLTSITLKDIVDDSEFLPFFESFLGSVPETQGSTFLEYSQTIESFKNPLEDATSEDIISGYSGISTMQLQEISSKFFHNNNLQNMKLLDEGLVKNIILFRNSFQINNDEDTFILARKSVLLLQTEAIKYLDDRFLPLFKKTPSFLKMLSTSHIISTDIYAHFLSRIGGVNNPEQNKIIKDNVKTDFMNPVRIFANPGITDALDNIVNGSGSKPHKSRISSNPRYSQLFGSENDNIFKDKLFDDENDNTSEISVVEDQLDHPRNMEKVSVSSGNSGLNPSQFYGSNNFRDNIASLTISIDQIEKELELLRHLILKADLTNNQMQLKILKKSQRTLLKELEMKELLKQQYMVQENGNSLFRKTKIYIRSYFSENSSNGLKEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMRQLQDLFPSKVKMSLKYHVTKTLLYEERKQKLEKYLRELLSISEICEDNIFRRFLTDPTPFKLNKEYMHDDILEEPLHEPIGSSNSTSNSSSVVDLQ---SSEDGGELNFYEDERHFFTDSGYPFYSQNKSFVKQICDLFISLFALNKANAGWLRGRAIITVLQQLLGSTIEKYIKVSIQKLRSEDQVFEAIVTFKNMLWGDNGLFERKRNETAEATRSEGERLRTEQLALTSLQRLFADTCGRVVGLRDSHEAAGRVHAMLQNPYLNASLLLEALDAILLDIICND------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *..:.: :*:: .* : . : .:: : : :: : : * ..:: .:: . *: : * . : : * . .. . ::. :: *: . : :::*:*: :: *:: :: ** * :: * : . ::. *::*. .: :: *. : . : : .: : * . :: * * : .: . .:. :: : .. . : : :*: . * :: : ::: : : * :*:. :. : . : ** . : :: : : . . :* :. * ::: * * : * * :: . : : . .. . . :: :.:::: . : : :: : . .* : *.. : . : :: :.. : . : :: . : :... * : * .:. :*: * . .* . .: : . : :.::: :*. :*. ..: .: : **: *:. *: . . .* : . . .:. ::. * * *. : : ::. : . *:* :::*:.:* * **:: *: :: : .*. : : : . :* .. * . ** * * * :.: :** : ::.. ::. **:. * *: :: :: :: : ", "identical_positions": 72, "similar_positions": 279, "identity": "5.57%" }, { "cls_id": "homologset.agr.MGI:2142624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A5PLL7-1", "uniprot_id": "PEDS1_HUMAN", "id": "A5PLL7-1", "name": "Plasmanylethanolamine desaturase 1", "aln": "----------------------MAG---AENWPGQQLELDEDE---------------ASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHNLVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREHHIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGTFTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGWLNYPLEKIGFWRRLEDLIQGLTGEKPRADDMKWAQKIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99LQ7-1", "uniprot_id": "PEDS1_MOUSE", "id": "Q99LQ7-1", "name": "Plasmanylethanolamine desaturase 1", "aln": "----------------------MAG---AEDAPGRQPELDEDET--------------AEGRRWGAQHAGARELAALYSPGKRFQEWCSVILCFSLIAHNLVHLLLLARWEHTPLVILGVVAGALVADFLSGLVHWGADTWGSVDLPIVGKAFIRPFREHHIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTQSPETLEQLYPWECFVFCLTIFGTFTNQIHKWSHTYLGLPYWVTVLQDWHVILPRKHHRIHHVAPHETYFCITTGWLNYPLEVIGFWRRLEDLIQGLTGEKPRADDMKWAQKIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B5J8-1", "uniprot_id": "A0A8M2B5J8_DANRE", "id": "A0A8M2B5J8-1", "name": "", "aln": "-----------------MKQGTMAAALLSETEIRHRSMAEEDPNGNEHG-----AAARSTAPRWGPQHAGARQLAKLYSPGKRLQEWICVILCLSLFIVNLSFLFLNFSTVHIYRIIFGIVTGIVTADFASGMVHWGADTWGSVDIPVIGKAFIRPFREHHIDPTAITRHDFIETNGDNCMITILPLAHMAYKFLSYPPDALAESYPWECFVFALAVFVTMTNQIHKWAHSYFDLPRWVTLLQDCHLVLPRKHHRIHHVSPHETYYCITTGWLNYPLDRVGFWRTMEWLIERLTGQRPRSDDLAWAKKTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3B5-1", "uniprot_id": "Q9V3B5_DROME", "id": "Q9V3B5-1", "name": "", "aln": "MAAKSDMDILANSMYEDDPNGNLAPATTKDKESVKPEELKVTPAGTKATSPPNSATLVSTSPRWGPQNKGAQELALLYSPGKRAQEIICVYTCIGLMIINLALIVRHLRLERISVAFLSALCGIITADFASGLVHWAADTWGSVDIPMIGKNFLRPFREHHLDPTSITRHDFIETNGDNFMVGIPILGYLAHYFYIRTPSEIQQHFGWIAYVFLCSIFVAMTNQIHKWSHTYWGLPRWVLLLQSCHIILPRKHHRIHHVAPHETYFCITTGWLNWPLERIRFWSTFELIIEHFTGLKPRDDDLKWAKKLT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : . : ***.*: **::** ******* ** .* *:.*: ** :. ::. : * : *** **:***.*******::*::** *:*******:***:************* :: : * :*: * .*. : : : * .:** :* ::*******:*:* .** ** :**. *::***********:*****:********:**: : ** :* :*: :** :** **: **:* ", "identical_positions": 129, "similar_positions": 63, "identity": "41.61%" }, { "cls_id": "homologset.agr.MGI:2142632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCQ2-1", "uniprot_id": "D3ZCQ2_RAT", "id": "D3ZCQ2-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAADTGSWCVYAVLRFFYSLFFPGLIICGVLCVYLVIGLWVIRRHLQRKK---KSASTSKNGKDQMVVAFFHPYCNAGGGGERVLWCALRALQKKYPDAVYVVYTGDIH----VSGQQILEGAFRRFNIKLVHP-VQFVFLRKRYLVEDSRYPHFTLLGQSLGSILLGWEALMQRVPDVYIDSMGYAFTLPLFK-YVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTNIVYPPCDVQTFLDIPLH----EKKVTPGHLLVSIGQFRPEKNHALQIKAFAKLLNEKAAESR--HSLKLVLIGGCRNKDDEFRVNQLRRLSENLG--VQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVIPHEGQ-------------------------ITGFLAESEEG--------------YAETMAHILSLSPEKRLRIRETAR-ASLSRFSDQEFEVAFLCSVGKLLT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TZM9-1", "uniprot_id": "ALG11_MOUSE", "id": "Q3TZM9-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAADTGSWCVYAVLRFFYSLFFPGLMICGVLCVYLVIGLWVIRWHLQRKK---KSVSTSKNGKEQTVVAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDIN----VSGQQILDGAFRRFNIKLAHP-VQFVFLRKRYLVEDSRYPHFTLLGQSLGSILLGWEALMQRVPDVYIDSMGYAFTLPLFK-YVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTNIVYPPCDVQTFLDIPLH----EKKVTPGHLLVSIGQFRPEKNHALQIKAFAKLLNEKAAELG--HSLKLVLIGGCRNKDDEFRVNQLRSLSENLG--VQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTVILAHNSGGPKLDIVIPHEGQ-------------------------ITGFLAESEEG--------------YADSMAHILSLSAEERLQIRKNAR-ASISRFSDQEFEVAFLCSMEKLLT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TAA5-1", "uniprot_id": "ALG11_HUMAN", "id": "Q2TAA5-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAAGERSWCLCKLLRFFYSLFFPGLIVCGTLCVCLVIVLWGIRLLLQRKK---KLVSTSKNGKNQMVIAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDVN----VNGQQILEGAFRRFNIRLIHP-VQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFK-YIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTNIVYPPCDVQTFLDIPLH----EKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESP--PSLKLVLIGGCRNKDDELRVNQLRRLSEDLG--VQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGD-------------------------ITGFLAESEED--------------YAETIAHILSMSAEKRLQIRKSAR-ASVSRFSDQEFEVTFLSSVEKLFK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW24-1", "uniprot_id": "ALG11_DANRE", "id": "Q7ZW24-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "-----MSAHDHFSLCLCDLIRLLWSLMLPCFYLSFLLTTILFLFIMGVRSWLQMKR---KTRRVQ-DGRP--AVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQG----VTAEEILDGARRRFNIRLPRP-VKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFR-YLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEAEPAGREAVKLVLIGGCRNQEDEDRVLMLRGLCQELG--IADRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGG-------------------------PTGFLADDEDN--------------YADAMERILSMSPATRLEMRRRAR-LSVSRFSDQEFEGSFLSAMEPLMSTLRA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP06-1", "uniprot_id": "Q9VP06_DROME", "id": "Q9VP06-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "---------------------MFLFLFLLWLLLSLVLVAVLS-FLFLRQWLLGRKN---KLHTSSENGIN---VGIFHPYCNAGGGGERVLWCAVRALQEKYQNARMVIYTGDID----ASPNSILQKAKNVFNIAVDSDNVKFVFLKQRHWIEAKNYPHFTLLGQSIGSMVVGLEALCRFPPDIYIDTMGYAFTYPLFR-YLAQSKVGCYVHYPVISTDMLKRVQQRQMSHNNKKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWDVPFKTHRVYPPCEVSHLKSLQHT----EKGDE--FIILSVGQFRPEKDHPLQLQAIYELRTLLAQDEALWNQIKLVIVGSCRNEDDYERLKNMQDLTKHLS--LENNVQFSVNVPYEDLLKLYQTAHIGIHTMWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIVETSAGS-------------------------QNGFLATDAVE--------------YAENILNIIVNNSE-MNGIRNAAR-ASVERFSEQEFEKNFLRAVSTLFTNN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53954-1", "uniprot_id": "ALG11_YEAST", "id": "P53954-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "MGSAWTNYNFEEVKSHFGFKKYVVSSLVLVYGLIKVLTWIFRQWVYSSLNPFSKKSSLLNRAVASCGEKNVKVFGFFHPYCNAGGGGEKVLWKAVDITLRKDAKNVIVIYSGDFVNGENVTPENILNNVKAKFDYDLDSDRIFFISLKLRYLVDSSTWKHFTLIGQAIGSMILAFESIIQCPPDIWIDTMGYPFSYPIIARFLRRIPIVTYTHYPIMSKDMLNKLFK----------MPKKGIKVYGKILYWKVFMLIYQSIGSKIDIVITNSTWTNNHIKQIWQS-NTCKIIYPPCSTEKLVDWKQKFG--TAKGERLNQAIVLAQFRPEKRHKLIIESFATFLKNLPDSVS---PIKLIMAGSTRSKQDENYVKSLQDWSENVLKIPKHLISFEKNLPFDKIEILLNKSTFGVNAMWNEHFGIAVVEYMASGLIPIVHASAGPLLDIVTPWDANGNIGKAPPQWELQKKYFAKLEDDGETTGFFFKEPSDPDYNTTKDPLRYPNLSDLFLQITKLDYDCLRVMGARNQQYSLYKFSDLKFDKDWENFVLNPICKLLEEEERG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : * : : : * : . . ..:************:*** *: .: . *:*:** .. :.**: . *: : : *: *: * :: . : ****:**::**:.:. *:: . **::**:**:.*: *:: :: : *.*** :*.***. : : :. : . *: *: :* :* *. : ::.**:** .** :* :****... : . : :.****** * * :.:: : . :**:: *. *.::* : :: :.: . :.*. *:.::.: : :*:::********.:** **:* : :.* *.** **** . . .**: . :: : .* . : : *: :**: :*: : : : ", "identical_positions": 113, "similar_positions": 148, "identity": "20.04%" }, { "cls_id": "homologset.agr.MGI:2142651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDR5-1", "uniprot_id": "D3ZDR5_RAT", "id": "D3ZDR5-1", "name": "Protein arginine N-methyltransferase 9", "aln": "MPNS--RP-RSRRSAGGGAGTAGRDRLVAQSLQSAEHCLGDQDFGTAYAHYLLVLSLAPELKEDVKETFQYTLFKWAEELHALNRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFNDAKENFYRVANWLVERWHFIMLNDTKRNEIYNAAIQKAVRLGSKTVLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEDGIRLLHMKSLDLEIPKHIPERVSLVVTETVDAGVFGEGIVESLIHAWEHLLLQPQTKGESGSWG-KYGKVIPASAVISGMAVECAEIRRHHRVSAKDIAGIHLPTNVRFQSPAYASVDPEETVEPYTTEKMSGIPGGYRPLTECFQIMKVDFNNLQELKSLATRKPHSLSVPAVKEGTLDAIMVWFVLQLDDEHSLSTSPSEETCWEQAVYPVQALEDYWIQPGDQVTMEASCHDCYLRIQGISILHLEHEMEVIKSFTKSKDLLSLGNEAELCSALANLQTSRPEALEQTCVLEPTEIALLNNIPYHEGFRTAMRKVLSSLAPETPSQPMEAHCQDMETN-----LESAPSTSDPFYVLDVSEGFSLLPILAGTLGQ----------VQPYSSVEKDQHCIALDLISEANHFPKETLEFWLRHIEDEAAVLQRPKSDKLWSIIILDVIEPSGLIQQEIMEKAAISRCLLQSGGKIFPQYVLMFGMLVESQTLVEESAVQGTEHTLGLNIAPFINQFQVPIRVCLDLSSLPCIPLSQPVELLRLDLMTPYLNTSNREVKVRVCRSGRLTAVPFWFHLCLDDEVRLDTSGEASHWKQAAVVLDNPIQVQAGEELVLSVEHHKSNISITVKQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U3W5-1", "uniprot_id": "ANM9_MOUSE", "id": "Q3U3W5-1", "name": "Protein arginine N-methyltransferase 9", "aln": "MPNS--RP-RPRRGAGGGAGAAGRDRLVARSLQSAEHCLGDQDFGTAYAHYLLVLSLAPELKDDVKETFQYTLFKWAEELHALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFNDAKENFYRVANWLVERWHFIMLNDTRRNMVYNAAIQKAVCLGSRTVLDIGTGTGILSMFAKKAGAQSVYACELSKTMYELACDVVAANKMENGIKLLHMKSLDIEIPKHIPERLSLVVTETVDAGVFGEGIVESLIHAWEHLLLQPKTKEENGNCG-KYGKVIPAGAVIFGMAVECAEIRRHHRVGAKDIAGIHLPTNVKFQSPAYTSVDTEETVEPYTTEKMSGIPGGYLPLTECFQIMKVDFNNLQELKSLATKKPHSLNVPAIKEGVLDAIMVWFVLQLDDEYSLSTSPSEETCWEQAVYPVQALEDYCIQPGDRVTMEASCHDCYLRIQGISILHLEHEMEVMKGFTKSKDLLSLGNEAELCSALANLQTSRPEALEQTCMLEPTEIALLNNIPYHEGFKTAMRKVLSSLAPELLWQPMDTHCQYMEMNSGSGQSDAAPSTADPFYVLDVSEGFSLLPILAGTLGH----------VKPYSSVEKDQHCIALDLIAEANHFPKETLEFWLRHIEDEAAVLQRPKSDKLWSIIILDVIEPSGLIQQELMEKAAISRCLLQSGGKIFPQYVLMFGMLVESQTLVEESAVQGTEHTLGLNIAPFINQFQVPIRVCLDLSSLPCVPLSQPVELLRLDLMTPYLNTSNKEVKVRVCRSGRVTAVPFWFHLCLDDEVRLDTSGEASHWKQAAVVLDNPIQVQAGEELVLSVEHHKSNVSIAVKP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P2P2-1", "uniprot_id": "ANM9_HUMAN", "id": "Q6P2P2-1", "name": "Protein arginine N-methyltransferase 9", "aln": "MSNS--RP-RSRRDAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKHDVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRVANWLVERWHFIMLNDTKRNTIYNAAIQKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLIHAWEHLLLQPKTKGESANCE-KYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLPTNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLATKKPDKIGIPVIKEGILDAIMVWFVLQLDDEHSLSTSPSEETCWEQAVYPVQDLADYWIKPGDHVMMEVSCQDCYLRIQSISVLGLECEMDVAKSFTQNKDLLSLGNEAELCSALANLQTSKPDAVEQTCILESTEIALLNNIPYHEGFKMAMSKVLSSLTPEKLYQTMDTHCQN-EMSSGTGQSNTVQNILEPFYVLDVSEGFSVLPVIAGTLGQ----------VKPYSSVEKDQHRIALDLISEANHFPKETLEFWLRHVEDESAMLQRPKSDKLWSIIILDVIEPSGLIQQEIMEKAAISRCLLQSGGKIFPQYVLMFGLLVESQTLLEENAVQGTERTLGLNIAPFINQFQVPIRVFLDLSSLPCIPLSKPVELLRLDLMTPYLNTSNREVKVYVCKSGRLTAIPFWYHMYLDEEIRLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKSNVSITVKQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B684-1", "uniprot_id": "A0ACD6B684_DANRE", "id": "A0ACD6B684-1", "name": "Protein arginine N-methyltransferase 9", "aln": "MPNATTRPKRTRRHRRAQREDAARNELVSRSLESAQQCLFSEDYGTAFVHYLLVLNLAPALKDFANESFRFTLFKWAEELDSLGRIQDLFDCYEQAMELFPVDEIIVNSMGEHLFRMGFRDEAAGHFYKALKLRPDFPEAKENFYRVANWLVERWHFLMLNDHGRNHKYQLAIKKAVEGGCSSVLDIGTGTGILGMCAKMAGAAEVYACELSKTMYELACEVLSANGMADCIKILHRKSLDMEIPKDIPNRVSLVVTETVDAGLFGEGIIETLIHAWKHLLLPPPNPGELLSSPSQTGRVIPAGATVFGVAVQCPEIRRHHRLCVSSVGGLDLSAVGQIYSPVSCLADTEDSTEPYTTERLSRLRGGYIQLTQPFTALDIDFNNVQELEGLCSREVVQLCLCVTQDGILDALAVWFQLHLDQDNHLSTGPQEETCWEQAIYPVQSTFN-SVKRGDEILVEVSCKDSYLRLCCVAIIRDGNTIHMDSATKGAPKSLPANPEVDLCSALAGLQTNQ-EKASLAFMLESSEIALLNNTAYHSSFQKAMSKLLDSLQSTRRQQ--ESNAQP-----------------DPVYVLDVSEGFSVLSLISAQLGFNKQIGSNSGLVKAYSSVEKEHHQNLLKLLAKGNGVLESALEFWLTHVEDDSAVLQRPATEKLWSAIILDCIETCGLIRQKLLEKASLARCLLEDGGQIFPERIVIHGMLVESDTLLLENAVQGTEPTLGFNIAPFINQFTVPVHMFLDLSTLECRQLSEPVELFTLDLMNSSANYTDKQVKVQVSTSGKVSAIPFWYQIHLDCWQSVSTYSKDSHWKQAAVVLQQPLTVSRGDWLQLSVRLHKSSISITAVKEEEPGANDVNTEVESATNDT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*: ** *.** . *.*:.**::**:**::** :*:***:.******.*** **. .:*:*::***:*****.:*.*****:.*****:**** **:* ******************:*:**:**.*** :******************:**** ** *: **:*** *. :*****:*****.* ** *** .***************:*::** * *::** ****:****.**:*:***********:*****:*:*****:**** * . * . : *:****.*.: *:**:*.*******: ..:.*:.*.: :: **. .*.*:: ******::* : *** **: * : :****:***:.*.::: .: : . ::* ***: *** *:**:: ***.*.********:**** : :: **.: :*.**:*.***: :::: :.: .. . . *. . *.:******.***.: : . : :**.:******* .**..*: ** *:*.** . * :::.* :*.**********:*.:::. ** *:.******::* *.*:::.* . :.:***** *:**::*:**** ::**** **** **..***:*:::***:::****:.**:***: :::.*:****:**: *.****** ***:********* **::: ****:* * **:****: ****.. * ::::*** *. **:::*:***::: ** :.* .: **********::*: *. *: * **:. ***.:**:. ", "identical_positions": 447, "similar_positions": 238, "identity": "50.8%" }, { "cls_id": "homologset.agr.MGI:2142662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923G5-1", "uniprot_id": "ZDHC7_RAT", "id": "Q923G5-1", "name": "Palmitoyltransferase ZDHHC7", "aln": "MQPSGHRLRDIEHHPLLTDNDNYDSASSSSSEADMADRVWFIRDGCGMVCAVMTWLLVVYADFVVTFVMLLPSKDFWYSVVNGVLFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSIHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLQMRTRKGGPEFSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WU6-1", "uniprot_id": "ZDHC7_MOUSE", "id": "Q91WU6-1", "name": "Palmitoyltransferase ZDHHC7", "aln": "MQPSGHRLRDIEHHPLLTDNDNYDSASSSSSETDMADRVWFIRDGCGMVCAVMTWLLVVYADFVVTFVMLLPSKDFWYSVVNGVLFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRLRRLQMRTRKGGPEFSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXF8-1", "uniprot_id": "ZDHC7_HUMAN", "id": "Q9NXF8-1", "name": "Palmitoyltransferase ZDHHC7", "aln": "MQPSGHRLRDVEHHPLLAENDNYDSSSSSSSEADVADRVWFIRDGCGMICAVMTWLLVAYADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGFQFISCVRGQWTECSDFSPPITVILLIFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLPTRPRKGGPEFSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHI1-1", "uniprot_id": "ZDHC7_DANRE", "id": "Q6DHI1-1", "name": "Palmitoyltransferase ZDHHC7", "aln": "MQSSGQRLRDVEQHQPLL---------SGGEEEVTAGRVWFIQDSCGMVCAFMTWSLVMYAEFVVNFVMLLPSKNFWYTLINGVAFNFLAVLALTSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCSIKPERAHHCSICKRCIRKMDHHCPWVNNCVGENNQRFFVLFTMYIASISLHALCLSGFHFFTCVKVQWNECSDFSPPVAVMLLIFLCLEALLFLTFTAVMFGTQIHSICNDETEIERLKNEKPTWERRVRWDGMKAVFGGPPSLLWFNPFAGLRLRMLMVRARRSGAEFSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.**:****:*:* * *...* *.*****:*.***:**.*** ** **:***.********:***:::*** ** ******:*****************************************.********************************:************* *:*** *.*::*::**: **.********::*:**:*****.***:*************************.********:**:***:**********:***.*:*:* * *.*:.*.****", "identical_positions": 235, "similar_positions": 47, "identity": "76.3%" }, { "cls_id": "homologset.agr.MGI:2142687", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2N6-1", "uniprot_id": "A0ABK0M2N6_RAT", "id": "A0ABK0M2N6-1", "name": "Carboxylic ester hydrolase", "aln": "MSCEGIQHLPSSAPGEGLSQDSWTGSQNVGRTLHSPSLWIRVRNSTDWSTCPCKMCLSFLFLVSLATCVVYG-----------------NPSSPPVVDTTKGKVLGKYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWS-FVKNTTTYPPMCSQDAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYTPADFTK---NSRLPVMVWIHGGG--MTLGGASTYDGRVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTK-DVRPAAKQIADMAGCETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQRDNKESYHFLSTVVDNVVLPKDPKEILAEKNFNTVPYIVGINKQECG-WLLPT-MMGFVPADVELDKKMAITLLEKFASLYGIPEDIIPVAIEKYRKGSD---DSIKIRDGILAFIGDVSFSIPSVMVSRDHRDAGAPTYMYEYQYYPSFSSPQRP---KHVVGDHADDLYSVFGAPILRDGASEE--EIKLSKMVMKFWANFARNGNPNGRG-----LPHWPQYDQKE-EYLQIG-ATTQQSQRLKAEEVAFWTQLLAK----RQPQPHHNEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R7R1-1", "uniprot_id": "M0R7R1_RAT", "id": "M0R7R1-1", "name": "Carboxylic ester hydrolase", "aln": "------------------------------------------------------MCLRSLFLVSLATCVVCG-----------------NPSSPPVVDTMKGKVLGKYASLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWS-FVKNTTTYPPMCSQDATKGQRMNDLLTNRKEKVHLQFSEDCLYLNIYTPADFTK---DSRMPVMVWIHGGG--LTQGGASTYDGQVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLSKNLYHRAISESGVVLITELFTK-DVRPAAKQIADMAGCKTTTSAIIVHCLRQKTEEELLEIMEKMNLIKLSSQRDTKESYHFLSTVIDDVVLPKDPKEILAEKNFNTVPYIVGINKQECG-WLLPT-MMRFVPPDVKLDKKMAIMLLEKFASIYGIPEDIIPVAIEKYRKGSD---DPIKIRDGILAFIGDALFCIPSVMVSRDHRDAGAPTYVYEYQYYPSFSSPQRP---KDVVGDHADDVYSVFGAPILRDGASEE--EIKLSKMVMKFWANFARNGNPNGRG-----LPHWPQYDQKE-EYLQIG-ATTQQSQGLKAEEVAFWTQLLAK----RQPQPHHNEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WU0-1", "uniprot_id": "EST1F_MOUSE", "id": "Q91WU0-1", "name": "Carboxylesterase 1F", "aln": "------------------------------------------------------MFLSTLFLVSLATCVICG-----------------NPSSPPVVDTAHGKVLGKHVNVEGFSQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWS-SVKNATTYPPMCSQDAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYTPADFSK---NSRLPVMVWIHGGG--LKLGGASSFDGRALSAYENVVVVAIQYRLSIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGYSVSILILSPLSKNLFHRAISESGVAFIPGMFTK-DVRPITEQIAVTAGCKTTTSAVIVHCMRQKTEEELLEIMHKLNLYKLSLQGDTKNSDQFVTSVLDGVVLPKDPKEILAEKNFNTVPYIVGINKQECG-WLLPT-MTGFLPADVKLDKKKAIALLEQFASMTGIPEDIIPVAVEKYTKGSD---DPDQIREGVLDAMGDVAFGVPSVIVSRGHRDTGAPTYMYEYQYYPSFSSPQRP---KNVVGDHADDVYSVFGAPILREGASEE--EINLSKMVMKFWANFARNGNPNGKG-----LPHWPKYDQKE-GYLHIG-GTTQQAQRLKEEEVTFWTQSLAK----KQPQPYHNEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23141-1", "uniprot_id": "EST1_HUMAN", "id": "P23141-1", "name": "Liver carboxylesterase 1", "aln": "------------------------------------------------------MWLRAFILATLSASAAWG-----------------HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWS-FVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTK---KNRLPVMVWIHGGG--LMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFG-WLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTD---DTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP---KTVIGDHGDELFSVFGAPFLKEGASEE--EIRLSKMVMKFWANFARNGNPNGEG-----LPHWPEYNQKE-GYLQIG-ANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y141-1", "uniprot_id": "Q9Y141_DROME", "id": "Q9Y141-1", "name": "Carboxylic ester hydrolase", "aln": "---------------------------------------------------MLMLF-VVELLVLLASSS----------------------VLSIEVDTELGRVRGANLTSR-LGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNMT---------------DVSEDCLRLNVYTKDLKG------RRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKD-NDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWN-PVLNWR-IVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVS-FHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFPLS-----SFH-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLA3-1", "uniprot_id": "Q9VLA3_DROME", "id": "Q9VLA3-1", "name": "Carboxylesterase type B domain-containing protein", "aln": "---------------------------------------------------MWRLCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQ-SGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWF-DTLDATFDGPKCPQLGLVSG---------------DVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPD-HQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWK-PVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKL--IDANRSLEALSNLYSDALTGFG-IHRFVHLAARSTKVYYYRFSYQGARSHIYYPEDAP-YGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEEN-LNAENYEIWKRLFPLN-----WRRQTKEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* *:: : * *:: * . . * *: :*:**:. *** *:*.: * ::: * *.* ..***** :*:** * **:*::* ** * :. * . *:*:::***. **::** ..: ** * *** *:*:: :* ***:*.*:*::* .**. :*:: ::**:::.*:*:.* *.. . . : : * * . ::.*:: * : . : . . . . : * : * . . :* .*. :.*:.: * : : : : : . ::* . : : . . .*. . . : * * : * : * * *:: :* : ..: * : .:: ::: ** :*:*: .* :. :. **.** * : :. :* :. ", "identical_positions": 101, "similar_positions": 144, "identity": "15.3%" }, { "cls_id": "homologset.agr.MGI:2142716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86UL3-1", "uniprot_id": "GPAT4_HUMAN", "id": "Q86UL3-1", "name": "Glycerol-3-phosphate acyltransferase 4", "aln": "MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAWATLRMERGAKEKNHQLYKPYTN---GIIAKDPTSLEEEIK-------------EIRRSGSSKALDNTP----EFELSDIFYFCRKGMETIMDDEVTKRFSAEELES--WNLLSRTNYN-FQYISLRLTVLWGLGVLIRYCFLLPLRIALAFTGISLLVVG-------------------------------------------------------------------------------TTVVGYLPNGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREADEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDTFKEEQQKLYSKMIVGNHKDRSRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2C8-1", "uniprot_id": "GPAT4_MOUSE", "id": "Q8K2C8-1", "name": "Glycerol-3-phosphate acyltransferase 4", "aln": "MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKTLLKIFAWATLRMERGAKERNHQLYKPYTN---GIIAKDPTSLEEEIK-------------EIRRSGSSKALDKTP----EFELSDIFYFCRKGMETIMDDEVTKRFSAEELES--WNLLSRTNYN-FQYISLRLTILWGLGVLIRYCFLLPLRIALAFTGIGLLVVG-------------------------------------------------------------------------------TTMVGYLPNGRFKEFLSKHVHLMCYRICVRALTAIITYHNRKNRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREKDEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDTFKEEQQKLYSKMIVGNHEDRSRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJ01-1", "uniprot_id": "A0A8I6AJ01_RAT", "id": "A0A8I6AJ01-1", "name": "", "aln": "MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAVFGVSFGIRKLYMKTLLKIFAVFVV----------VHLFCLFS----GIIAKDPTSLEEEIK-------------EIRRSGSNKALDKTP----EFELSDIFYFCRKGMETIMDDEVTKRFSAEELES--WNLLSRTNYN-FQYISLRLTILWGLGVLIRYCFLLPLRIALAFTGISLLVAG-------------------------------------------------------------------------------TTVVGYLPSGRFKEFLSKHVHLMCYRICVRALTAIITYHNRKNRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREKEEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDTFKEEQQKLYSKMIVGNHEDRSRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4LGJ9-1", "uniprot_id": "A0A0B4LGJ9_DROME", "id": "A0A0B4LGJ9-1", "name": "", "aln": "---------MIAVLLDIFWIPIGGFLSFLIFISAIN-KSIGVRKAYVNLLLRIFEYGRVSIETASKE-NQHIQNPKTDDKQGVQLVDDADSKEGTNGATLITRDAVLLPQPQEPAPEKPVSSTKD-EINFDFEKCLDYVKSGVEAIIEDDVTSRFEAEELKS--WNMLTRTNRH-YEFISWKITSIWVFGFFIRYVILMPLRVLVCFVGVLFAVLSSSIVACLPFRFVRLSLASLSFKITFRLISSSMSSFIKFHNKQYKPTVSGFCVANHTSPLDVAILSTDCTYSLVVWLTVCTAAVGYLKDGPFKRDLVHKVLGMCFGVLSSAISAVITYHNEDNRP-SSGICVANHTSPIDVLVLMCDSTYSLIGQRHGGFLGVLQRALARASPHIWFERGEAKDRHLVAERLKQHVSDPNNPPILIFPEGTCINNTSVMQFKKGSFEVGGVIYPVAIKYDPRFGDAFWNSAKYSMMQYLYMMMTSWAIVCDVWYLPPMYRQEGESAIDFANRVKSVIAKQGGLIDLVWDGQLKRMKPKKEWREIQQVEFANRLKSDST-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRC1-1", "uniprot_id": "Q9VRC1_DROME", "id": "Q9VRC1-1", "name": "Phospholipid/glycerol acyltransferase domain-containing protein", "aln": "--------------------MLIQLVFLGILLWASF---FWLQCRYLDVLELLFAWIGN-----------QLAETRRR--RAREERCRLGKKWAVG--------------NKGDGMEKLLSPPIKNRLNIRVEQCCDFITAGLGLVLEDDVTQRFVAPPSPAGEWNLLTRNLRQRNRYLSWRLRTVWLLGWVVRYGLLLPFRTIGCWL-CLFMISG------------------------------------------------------------------------------VSMLLGHIPDWCFKKKLVELVLRQCFRITAACLPMIRRFHNTEYRP-TKGICVCNHTSPLDVLVLMCDANYSLTGQVHTGILGVLQRALSRVSHHMWFDRKELADREALGLVLRLHCSMKDRPPVLLFPEGTCINNTAVMQFKKGSFAVSDVVHPVAIRYDRRFGEAYWDSTRYSMLRYMLMVVSSWCICCDVWYMPALSRCNDESPVEFSNRVKAAIAAQANIDDLPWDGNLKRWSPVRDWQ---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . *:: * : :: *:. * :* :: . . : : . .* :. . :: ... : *: :::*:**.** * : **:*:*. : .::* :: :* :* .:** :*:*:* .: : : . : :*:: . **. : . * *: : .:. : :*: . ** . ****.*****:**::* .*. *:: ** * *::**:***: :.. *:**:* * **. :. * * . .. *:*:**********:** ****** :. .::****:** :**:*:*:*::*.*: *: :::**.* *.***:*.: * *..::*:****:.** *..: ** *** *** . :: ", "identical_positions": 125, "similar_positions": 137, "identity": "22.4%" }, { "cls_id": "homologset.agr.MGI:2142747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "H1UBN0-1", "uniprot_id": "CPNE7_RAT", "id": "H1UBN0-1", "name": "Copine-7", "aln": "MSGDSER--TVAPGVVPAPCASKVELRLSCRHLLDRDPLTKSDPSVVLLQQAQGQWLQVDRTEVVKSSLHPVFSKVFTMDYYFEEVQKLRFEVYDTHGPSGLSCQDDDFLGGMECTLG---------------------------------------------------------------------------QIVAQKKMTRPLLLRFGRNAGKSTITVIAEDISGNNGYVELSFQARKLDDKDLFSKSDPFLELYRVNDDGSEQLVYRTEVVKNNLNPVWEPFKVSLNSLCSCEETRPLKCLVWDYDSRGKHDFIGDFTTTFAEMQKAFEEEQ-AQWDCVNAKYKQKKRNYKNSGVVILADLKLHRVHSFLDYIMGGCQIHCTVAIDFTASNGDPRNSCSLHHINPYQPNEYLRALVAVGEVCQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARMAAAEERTGEASQYYILLILTDGVVTDMSDTREAIVRASHLPMSVIIVGVGNADFTDMQILDGDDGILRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHKDLPPRSLGGQTGEAGPSSAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VE82-1", "uniprot_id": "CPNE7_MOUSE", "id": "Q0VE82-1", "name": "Copine-7", "aln": "MSGDSER--AVAPGVVPAPCASKVELRLSCRHLLDRDPLTKSDPSVVLLQQAQGQWLQVDRTEVVKSSLHPVFSKVFTVDYYFEGVQKLRFEVYDTHGPSGLTCQDDDFLGGMECTLG---------------------------------------------------------------------------QIVAQKKMTRPLLLRFGRNAGKSTITVIAEDISGNNGYVELSFQARKLDDKDLFSKSDPFLELYRVNDDGSEQLVYRTEVVKNNLNPVWEPFKVSLNSLCSCEETRPLKCLVWDYDSRGKHDFIGDFTTTFAEMQKAFEEEQQAQWDCVNAKYKQKKRNYKNSGVVILADLKLHRVHSFLDYIMGGCQIHCTVAIDFTASNGDPRNSCSLHHINPYQPNEYLRALVAVGEVCQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPKVQLYGPTNVAPIISKVARMAAAEESTGEASQYYILLILTDGVVTDMSDTREAIVRASHLPMSVIIVGVGNADFTDMQILDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHKELPPRSLGAQTGEAAASSAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBL6-1", "uniprot_id": "CPNE7_HUMAN", "id": "Q9UBL6-1", "name": "Copine-7", "aln": "MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQPAQKWLLQVVMRVSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAVRWWTCRGGHTQGWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQ-AQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F725-1", "uniprot_id": "E7F725_DANRE", "id": "E7F725-1", "name": "", "aln": "MSDSQEATSPVAGIGGPAACVCKVELRVSCKSLLDRDTLNKSDPCVILMVQNQGQWTELDRTEVIKSNLNPVFAKVLMLDYYFEEVQKLRFEVYDIHGAHSIGTRDDDFLGGVECTLG---------------------------------------------------------------------------QIVAQKKMMKPLLLKYGKYAGKSTITIHAEEISGNNGYVELSFCAKKLDDKDLFSKSDPFLEIYRINDDGTEQLVHRTEVIKNNLNPVWEPFKVSLISLCSCDDERKLKCLVWDYDSRGKHDFIGEFYTNFKEMQKISSGNK-VTWECINPKYKLKKKNYKNSGLVILSDLKLHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALIAVGEICQDYDSDKRFSALGFGARIPPNYEVSHDFAINFNPEDDECEEIQGVVEAYQNCLPKIQLYGPTNVAPIINRIAKQAAGKEPIKDASLYHILLILTDGVVTDMADTREAIVRASYQPMSIIIVGVGNADFTDMQILDGDDGVLRSPKGEPVLRDIVQFVPFRDFKTASPAALAKCVLAEVPKQVVEYFSHKAIPPMNPVLNSSPNSIANTPE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 406, "similar_positions": 96, "identity": "63.94%" }, { "cls_id": "homologset.agr.MGI:2142763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VLZ7-1", "uniprot_id": "C4D21_DROME", "id": "Q9VLZ7-1", "name": "Probable cytochrome P450 4d21", "aln": "-------------------------MWILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDYFNKYG-KT--FRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLK--NYADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERRAILERAR----------------------------------------ADGTYKPLI----------------MGDDDIGGKAKMTLLDILLQATID-NKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLG-PDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIG-----EITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKA------------------------------TYTFILSSSTGNNVGLKPRTRVK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W011-1", "uniprot_id": "C4D20_DROME", "id": "Q9W011-1", "name": "Probable cytochrome P450 4d20", "aln": "-------------------------MWLTLITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYG-KT--FRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLR--KVADGKTAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAK----------------------------------------ADGTYRPLS----------------LGDAEIGSKSQMALLDILLQSSIN-NQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLG-PDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIG-----DKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHN-TFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKP------------------------------MLNFILRSASGINVGLRPRKALR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O46051-1", "uniprot_id": "C4D14_DROME", "id": "O46051-1", "name": "Probable cytochrome P450 4d14", "aln": "-------------------------MYLELFAILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKTIFDMQFRLIAEFG-KN--IKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLY--DRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKNMHDFTNSVITERRELLQKAI----------------------------------------ADGGDADAA----------------LLN-DVGQKRRMALLDVLLKSTID-GAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIG-DDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLD-----GKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFS-MERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQP------------------------------VLNVILRSTTGINCGLKPRVY-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q27589-1", "uniprot_id": "CP4D2_DROME", "id": "Q27589-1", "name": "Cytochrome P450 4d2", "aln": "----------------------MLGVVGVLLLVAFATLLLWDFLWRRRGNGILP-----GPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYG-RL--YRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQ--SRADGMTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNS----------------------------------------KE--TTPEE----------------EVN-FLGQKRRMALLDVLLQSTID-GAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLG-EDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIR-----GKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFD-ADVP-QIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRH------------------------------SMNIVLRSANGVHLGLKPRA------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS79-1", "uniprot_id": "CP4D8_DROME", "id": "Q9VS79-1", "name": "Cytochrome P450 4d8", "aln": "------------------------MLLFLLVVLLFGAGWIIHLGQADRRRKVAN---LPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKFG-HL--QRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLA--QKANGNT-FDVYRSICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKVIEKRRQALE--------------------------------------------DQQSKLMD----------------TADEDVGSKRRMALLDVLLMSTVD-GRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLG-TDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERHE---NGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVEC------------------------------IVNIVLRSETGFQLGMRKRKHN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q27606-1", "uniprot_id": "CP4E2_DROME", "id": "Q27606-1", "name": "Cytochrome P450 4e2", "aln": "----------------------MWFVLYIFLALPLLL-VAYLELSTFRRRRVLN--KFNGPRGLPLMGN-AHQMGKNPSEILDTVFSWWHQYG-KD-NFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLK--TVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAP--DYPAYSRTLKTLQDFTNEIIAKR----IEAH----------------------------------------KSGAVSTN-------------------AGDEFTRKKMAFLDTLLSSTID-GRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVID-----GDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFE----LEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKERH------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4T5-1", "uniprot_id": "CP4E1_DROME", "id": "Q9V4T5-1", "name": "Probable cytochrome P450 4e1", "aln": "----------------------MWIVLCAFLALPLFL-VTYFELGLLRRKRMLN--KFQGPSMLPLVGN-AHQMGNTPTEILNRFFGWWHEYG-KD-NFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLK--KVADGGNIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAP--EYPEYSKTLKTLQDFTNEIIAKR----IEVR----------------------------------------KSGLEVGI-------------------KADEFSRKKMAFLDTLLSSKVD-GRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVID-----GDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFD----REKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMKQRLVCDST-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL92-1", "uniprot_id": "CP4E3_DROME", "id": "Q9VL92-1", "name": "Cytochrome P450 4e3", "aln": "----------------------MWLAVLALLVLPLIT-LVYFERKASQRRQLLK--EFNGPTPVPILGN-ANRIGKNPAEILSTFFDWWYDYG-KD-NFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLK--KASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTP--EFSAYQKTLKTLQDFTYDIIEKR----VYAL----------------------------------------QNGGSKED-------------------HDPSLPRKKMAFLDTLLSSTID-GRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMG-HDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDIN-----GSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFE----EEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRERRS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33269-1", "uniprot_id": "CP4D1_DROME", "id": "P33269-1", "name": "Cytochrome P450 4d1", "aln": "----------------------MFLVIGAILASALFVGLLLYHLKFKRLIDLIS--YMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYS-KDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTP--LARAEKKALNVLHQFTEKIIVQRREELIREG----------------------------------------SSQESSND-------------------DADVGAKRKMAFLDILLQSTVD-ERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVG-NDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEIN-----GKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEP---------------------------PVLIAELILRTKEPLMFKVRERVY-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYY4-1", "uniprot_id": "C4G15_DROME", "id": "Q9VYY4-1", "name": "Cytochrome P450 4g15", "aln": "------MEVLKKDAALGSPSSVFYFLLLPTLV------LWYIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPASSVFRTV-IRKSAPFE---HIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKLR---AED-GRTFDCHDYMSEATVEILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTR--YYKEQGRLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKDKEKASPVAGLSYGQSAGLKDDLD-VEDNDIGEKKRLAFLDLMLESAQN-GALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFG-D-SQRPATFQDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNSG---NYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLP-ERQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFK----------------------------LQADIILKREEGFRVRLQPRTS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3S0-1", "uniprot_id": "CP4G1_DROME", "id": "Q9V3S0-1", "name": "Cytochrome P450 4g1", "aln": "MAVEVVQETLQQAASSSSTTVLGFSPMLTTLVGTLVAMALYEYWRRN-SREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLNKYG---ETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMG---LEA-GKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTK--LREKGDRMMNIILGMTSKVVKDRKENFQE-------------------------------------ESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFG-DNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASG---PYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLP-ERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFK----------------------------LQADIILKLENGFNVSLEKRQYATVA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXY0-1", "uniprot_id": "CP4S3_DROME", "id": "Q9VXY0-1", "name": "Probable cytochrome P450 4s3", "aln": "------MSTLALVAFVLWAAFLRYLPKILNFL-----------------RLQRFAKTLPG----PTIGELIANVKKG--EILNWLKELREKHG---PVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLR---TKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTK--PGKEREAALKVLHDETNRVIRLRREQLIQ------------------------------------------ERNEWKPEA-----------------EQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEG-R---------EKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVG-----KLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLV-NEKQ-MHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDK-DHQPK----------------------------PLAELVTKSGNGIRLRILPRDENGTTA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A2RRT9-1", "uniprot_id": "CP4V2_RAT", "id": "A2RRT9-1", "name": "Cytochrome P450 4V2", "aln": "-MLWLWLGLSGQKLLLWGAASAVS---VAGATVLLNILQMLVSY-ARKWQQMRPIPSVAR--AYPLVGHALF-MKPNNTEFFQQIIQYTEEFR-HLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFMYKFLQPWLGLGLLTSTGSKWRARRKMLTPSFHFTILEDFLDVMNEQANILVNKLE---KHVNQEAFNCFFPITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMFK--EGRDHKKGLKSLHTFTNNVIAERVNARKAEQ------------------------------------DCIGAGRGPLP------------------------SKTKRKAFLDLLLSVTDEEGNKLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFG-RS-HRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAG-----YKISKGTEAVIIPYALHRDPRYFPDPEEFQPERFFP-ENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFWIESNQKREELG----------------------------LAGDLILRPNNGIWIKLKRRHEDDP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBW0-1", "uniprot_id": "CP4V2_MOUSE", "id": "Q9DBW0-1", "name": "Cytochrome P450 4V2", "aln": "-MLWLWLGLSGQKLLLWGAASAVS---LAGATILISIFPMLVSY-ARKWQQMRSIPSVAR--AYPLVGHALY-MKPNNAEFFQQLIYYTEEFR-HLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLE---KHVNQEAFNCFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFK--EGRDHKRGLKCLHTFTNNVIAERVKERKAEE------------------------------------DWTGAGRGPIP------------------------SKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFG-RS-HRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGG-----YKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFP-ENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELG----------------------------LAGDLILRPNNGIWIKLKRRHEDDP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWL3-1", "uniprot_id": "CP4V2_HUMAN", "id": "Q6ZWL3-1", "name": "Cytochrome P450 4V2", "aln": "-MAGLWLGLVWQKLLLWGAASALS---LAGASLVLSLLQRVASY-ARKWQQMRPIPTVAR--AYPLVGHALL-MKPDGREFFQQIIEYTEEYR-HMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLE---KHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFK--EGWEHKKSLQILHTFTNSVIAERANEMNANE------------------------------------DCRGDGRGSAP------------------------SKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFG-KS-DRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG-----YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFP-ENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELG----------------------------LEGQLILRPSNGIWIKLKRRNADER--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA27-1", "uniprot_id": "CP4C3_DROME", "id": "Q9VA27-1", "name": "Cytochrome P450 4c3", "aln": "MSSKVITSLMAESILLSKVGQVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIE-MNVDHDELFNRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLA---VEVGSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTA--EYKLHQSYINTLHGFSNMVIRERKAELAILQ------------------------------------ENNNNNNNNAPDA------------------YDDVGKKKRLAFLDLLIDAS-KEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFG-DDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGG-----KIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLP-ENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLT----------------------------LLGELILRPKDGLRVKITPRD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V558-1", "uniprot_id": "CP4P1_DROME", "id": "Q9V558-1", "name": "Cytochrome P450 4p1", "aln": "------------MIILWLILALSALLYWLHRANKDYHILSFFTKRIRLKDGTPVEIIAPIAKGKTIFGNTLDLYGRDHAGVFNYSRER-AKEMGTS--YIEYVFGKAIYNIIDADSAENVLNHPNLITKGLVYNFLHPFLRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFE----GQDEVTITLHDVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFEMFA--AK-DFASALDVVHRFSSEIIAKRRDLLKDELDK--------------------------------------SSSTADDDG--------------------FVS-KKRFAMLDTLIYAEKD--GLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDL--SNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELAN----GLILPKGAQITIHVFDIHRNAKYWDSPEEFRPERFLP-ENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDPQKIV----------------------------FHTGITLRTQDKIRVKLVRRT------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V559-1", "uniprot_id": "CP4P3_DROME", "id": "Q9V559-1", "name": "Probable cytochrome P450 4p3", "aln": "------------MLILWLVGAFIVLIQWIYRLNRDYCILGFFAKRIRTKNGQNPESIAPLVKGSTIFANSFDLYGKDHSGVFEHSRDC-AKKLGKS--YAEYAMGTAIYNVIDADSAERVLNDPNLINKGTIYDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESLKFLEQFK----GNDEAIISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKMFA--EK-DYASALDVVHGFSSEIIAKRRDQLNDEIDSR------------------------------------GNTQTAEDEL--------------------FTS-KKRFAMLDTLILAEKD--GLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDEL--NILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSN----GLILPKGSQIFVHVFDIHRNPEYWDSPEEFRPERFLP-ENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIV----------------------------FQTGLTLRTKNQIHVKLVRRK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V557-1", "uniprot_id": "CP4P2_DROME", "id": "Q9V557-1", "name": "Probable cytochrome P450 4p2", "aln": "----------MMICLLWISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDLLGKDTDQVFTHLRQL-AKNSGDS--YLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFVSQFQ----GQNEVVVSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVYNMFT--GH-KYNAALKVVHEFSREIIAKRRVLLEEELENR------------------------------------RATQTADDDI--------------------CVIRKKRFAMLDTLICAEKD--GLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDL--SNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELEN----GLILPKRSQINIHVFDIHRNPKYWESPEEFRPERFLP-QNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIV----------------------------FQVGITLRFKNKIKVKLVRRNCV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMS9-1", "uniprot_id": "C4AC1_DROME", "id": "Q9VMS9-1", "name": "Probable cytochrome P450 4ac1", "aln": "----------MWIALLGIPILLAVLTLLLKHINKTYFILS-LTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILNFTPASVFNFVRESTAKAKGQN--YLWYFLYAPMYNVVRPEEAEEVFQSTKLITKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLE----KNLDAELELNQVIPPFTLNNICETALGVKLDDMSE-GNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYG--DYRKHLQNLRIVHDFSSRIIERKRQQFQ-------------------------------------------QKQLGEVDE--------------------FGR-KQRYAMLDTLLAAEAD--GQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVEN-LPEDS--DDISMFQFNKLVYLECVIKESLRMFPSVPFIGRQCVEETVVN-----GMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLP-ENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLT----------------------------FENGIVLRTQENIKVKLSKRVK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMS7-1", "uniprot_id": "C4AC3_DROME", "id": "Q9VMS7-1", "name": "Probable cytochrome P450 4ac3", "aln": "----------MWIALLGSSLLIGALWLLLRQLNKTYFILS-LCKRVRTADGSPLESKVFVVPGKTRFGNNLDLLNLTPANIFSYIRESTAKANGQN--YIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPFLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKILD----KNVGFELELNQIIPQFTLNNICETALGVKLDDMSE-GNEYRKAIHDFEIVFNQRMCNPLMFFNWYFFLFG--DYKKYSRILRTIHGFSSGIIQRKRQQFK-------------------------------------------QKQLGQVDE--------------------FGK-KQRYAMLDTLLAAEAE--GKIDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQD-LPEDI--DEVSMFQFNELIHLECVIKESLRLFPSAPIIGRTCIEESVMN-----GLVLPKNAQISIHIYDIMRDARHFPKPNQFLPERFLP-ENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLEDLT----------------------------FENGIVLRTQQNIKVKFEARVK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMS8-1", "uniprot_id": "C4AC2_DROME", "id": "Q9VMS8-1", "name": "Probable cytochrome P450 4ac2", "aln": "---------MFLEVLFAAPLVIFIFRKLWAHLNRTYFILS-LCKRIRTEDGSLLESKIYVAPSKTRFGNNFDLVNFTSESIFNFMRDASAKAKGRN--YLWYFFHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLH----QSVNMELELNQVIPQFTLNNVCETALGVKLDDLSE-GIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFG--DYRKQVNNLKIAHEFSSNIIEKRRSLFK-------------------------------------------SNQLGQEDE--------------------FGK-KQRYAMLDTLLAAEAD--GQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKY-LPDDS--DDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVN-----GLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFP-ENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPVTLLDDLT----------------------------FENGIVLRTKQNIKVKLVHRENK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . :: * * :: *:* * :*. :: ** *. : : . : . ::: .:*:* . . : : : :: : : ::** :: . : ::*..:: * ***: :. * * : : : :: *:.*. * ..* : : : : .* * *:. .**:* :.*:*:*:. : * : ::: : . . . * ", "identical_positions": 35, "similar_positions": 83, "identity": "5.49%" }, { "cls_id": "homologset.agr.MGI:2142765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWL6-1", "uniprot_id": "A0A8I5ZWL6_RAT", "id": "A0A8I5ZWL6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRGAWMCRQYDDGLKIWLAAPRENEKPFID--------SERAQKWRLSLASLLFFTVLLSDHLWFCAEAKLTRTRDKEHHQQQQQQQQQQQQQQQQQQQQQQRQQQRQRQQQRQRQQEPSWPALLASMGESSPAAQA----------------------------HRLLSASSSPTLPPSPG--GGGGS----------------------------------------------------------------------------------KGNRGKNNRSRALFLGNSAKPVWRLETCYPQGASSGQCFTVESADAVCARNWSRGAAAGEEQSSRGSRPTPLWN-----------------------------------LSDFYLSFCNSYTLWELFSGLSSPSTLNCSLDVVLTEGGEMTT---------CRQCIEAYQDYDHHAQEKYEEFESVLHKYLQSDEYSVKSCPEDCKIVYKAWLCS---QYFEVTQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNCRKTIPCKQYCLEVQTRCPFILPDNDE----VIYGGLSSFICTGLYETFLTNDEPECCDIRSEEQSTPRPKGTVDRRD-SCPRTSLTVSSATRLCPGRLKLCVLVLILLHTVLTASAAQNSTGLGLGGLPTLEDNSTRED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CCS2-1", "uniprot_id": "NALF1_MOUSE", "id": "Q8CCS2-1", "name": "NALCN channel auxiliary factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRGAWMCRQYDDGLKIWLAAPRENEKPFID--------SERAQKWRLSLASLLFFTVLLSDHLWFCAEAKLTRTRDKEHHQQQQQQQQQQQQQQQQQQQQQQRQQQRQRQQQRQRQQEPSWPALLASMGESSPAAQA----------------------------HRLLSASSSPTLPPSPG--GGGGS----------------------------------------------------------------------------------KGNRGKNNRSRALFLGNSAKPVWRLETCYPQGASSGQCFTVESADAVCARNWSRGAAAGEEQSSRGSRPTPLWN-----------------------------------LSDFYLSFCNSYTLWELFSGLSSPSTLNCSLDVVLTEGGEMTT---------CRQCIEAYQDYDHHAQEKYEEFESVLHKYLQSDEYSVKSCPEDCKIVYKAWLCS---QYFEVTQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNCRKTIPCKQYCLEVQTRCPFILPDNDE----VIYGGLSSFICTGLYETFLTNDEPECCDIRSEEQTAPRPKGTVDRRD-SCPRTSLTVSSATRLCPGRLKLCVLVLILLHTVLTASAAQNSTGLGLGGLPTLEDNSTRED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1AL88-1", "uniprot_id": "NALF1_HUMAN", "id": "B1AL88-1", "name": "NALCN channel auxiliary factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRGAWMCRQYDDGLKIWLAAPRENEKPFID--------SERAQKWRLSLASLLFFTVLLSDHLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQR-----------RQQEPSWPALLASMGESSPAAQA----------------------------HRLLSASSSPTLPPSPGDGGGGGG----------------------------------------------------------------------------------KGNRGKDDRGKALFLGNSAKPVWRLETCYPQGASSGQCFTVENADAVCARNWSRGAAGGDGQEVRSKHPTPLWN-----------------------------------LSDFYLSFCNSYTLWELFSGLSSPNTLNCSLDVVLKEGGEMTT---------CRQCVEAYQDYDHHAQEKYEEFESVLHKYLQSEEYSVKSCPEDCKIVYKAWLCS---QYFEVTQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNCRKTIPCKQYCLEVQTRCPFILPDNDE----VIYGGLSSFICTGLYETFLTNDEPECCDVRREEKSNNPSKGTVEKSG-SCHRTSLTVSSATRLCNSRLKLCVLVLILLHTVLTASAAQNTAGLSFGGINTLEENSTNEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5P3-1", "uniprot_id": "A0ACD6B5P3_DANRE", "id": "A0ACD6B5P3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSGARKCRQRDNGLKNWCAP-RENEKPFTD--------SERAQRWRLSLASLLFLTVLLSDHLWFCAEAKMTRTRDK-----------------------------------------------LASED---------------------------------------MSANHRPDLPPTHS------------------------------------------------------------------------------------------SLRRNED---AIFVVNSTKPLWQLETCHTDSLSEN-CFTFVDADHLCR-----GLSETEG--------TRWVN-----------------------------------MSDLYLSFCNSYSLMDLLYGSLSPDNLNCSLDAVMD--GDQNR---------CSLCVQAYQRYDLHAQEKYEEFEMMTDKY-ETDVYSVRTCMEECKTVYKPWLCA---QYFQSPR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SACSHKIPCEQYCLEVQQRCPFILPDNDD----LIHGGTPSFICTGLSKRPDTNQEPECCDVRWDQMSNNLSRGTLKRTQPSCQHTSVTSSGAPRLGHSRLKLCLLVLVLLHTVATMTANQNSTCLTT--IFPLDDNAPREE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7V0-1", "uniprot_id": "Q9I7V0_DROME", "id": "Q9I7V0-1", "name": "", "aln": "MRPGPGLVVMALAFISGARRGSSSSISSATATPTAAATSAAAAAAAAATSAASTSAAAAAAANTAGGRKRGRSGGGVGGGGVATTLPSTGESSSSSFVRSSGSYLLPIFLPHYLDFALQFHPQLPPREYSQGRAHSESWASSRIADRLQQRRRRRESSSSRDIAGRAGGTGGSGADSGGLAATTGHSTESSEANNQEDGEDRGLTVQFPSSQAYDEDQDIFALVAEDDLLSEESFDRLIKLNEDADEEDYNLQQQHLPQHKQQQQQPGAETEIDTEPESETETETETETDTEAEVEVERETEQQQQDESRLIDEGVLQHSDHSNSHSKEFAISYDNNNNKREASGHILDAQTAQLIGHKDNTVPAVASTESAGGGSITTSLPAPVDLKKSILGTATSLTRLNPWISACDLAQPGTGTDLQGQCSAGTLPMAWVDEGPGPPTCPRSCAEQQQQKPVASKAKRSATSNNKVKYFVNYKTTQMRLRRAGDHAMDATDSHSPLASERPPSTTDDQDVDVSSTTEEAEPEPTLSYSHLHAQEPVLAHQQDPREREQEQQEQQQCLEYLGDSAESSPQHLCGLQSPGHLLERLKVLRLRNCCERSVFSSLHTLALNASLTDRQECVRVLSDLLDVDGLANRITCELAEILFRFDCRQVYSLINQCDDCKEAYRRWVCSTLVPYFAEPKDVSPQPKDEGQGKGKRSARSAASAEATAMADGIKHKSLKLISNNNKSNNGNNMNERQINQKHDKSSNANANANSNASKDIDRSAEEAIDRDLVQTFYDVVGLSKPRHGEEEVLPENEAGLGRSADSEVDKGAEPDRKRSRNREAELELDTEAEAEQQSNNFISTANNSDPRATDPVISKLQKRSTRKTEFRKRRRIRPCLSVCQTVEQKCPYLLPADRAPALPTQYAGEPTFLCLDQN-IPETGAQLEKSSYGPNDCCYSYCNGPASGICTVCQDFGQPGTEEREMAGNSTRRVHNITLSLSSHPGEHARAKSVALALRNVSQTGSDPDAVETLLDRLPYYASHDGIFYYDEEGEMPHASLSGDCAVVPAATTRCTIPYYASGTGAVAKPPTQLLVWLSALLGLLSSCGAARQRWSCQWSSGCGGHRARSRQAVACEANCHEQELVKSRSCSQRSPKVRREKPGQDQDAELVAFRTWLWSSSWHAYKLTCSKIRYFSSRSRFKGETRAARSANSKDPSGLQWSRAAGCTRTRNYRFFYYYNYNINDWWRRWWRCLSSGAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..: ::* . : ..:.: : :* . *: *: :. .:. : : ::.: ::: * . . : . :*. . . * . . :. * .. :*. . .. . ..: :: . . * . .. :*. : .*: **. *: * :. * *:. *: : :: : **: . ::** .*: *:*: ** .: : ** . * *: :**::** : :.* .:*:* . *. : * .. :: .*. . * . . : .: . : : : * : * ::. * : .:. : ", "identical_positions": 46, "similar_positions": 129, "identity": "3.7%" }, { "cls_id": "homologset.agr.MGI:2142786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYH9-1", "uniprot_id": "A0A0G2JYH9_RAT", "id": "A0A0G2JYH9-1", "name": "", "aln": "MAASVQAAAAPSGVLGTCGLEQILEALKLLLSPGGSGSTSLQNTKHDVLLETLKSNLSALEAKFLKDAQWKKLKTLRDEIADKAEWPQSSEDITWSFTSQTLLLLLCLKEIMTRLVAEFNPGKPNPRTPEAAPALSPDTLSVSQQKTFQSVLQFVVTLGVCPYLMPGVGVPLRDRTEFGAVVQGIVRLEAAPHATRRLYICCRVLLDLAQHASLGSLIFCRHFGDIAAGLCQLGFCPTKRKPPVPVEEVLTEEERTLSRQALRDILDQVYQPLAVRELLILQGGSPQSCTDVKTKLRC--PAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEATAADWKKCDLIAKILASCPQQSLSPESYYKDICPQILDLFHLQDKLTARQFQRVATTTFTTMLRERPELAPKYLLQPMLAPLHRCSTTAEIPESDMVPGTVLVTEEELSRCVEDVFKVYVVANEPLPVLLDSLLPLLGVFFSLYCFTQQSASHIRSLCQEILLWALVKLERKRAIASLRGFSGLDKAVPALHPQCQFRAATHGGIVITVKEALSD-DEDEALYQKVSSEQSQMEHLGDLLLHCQPCGLAGDFFIFCLKELSHLLEENEAEFTPKPPCSTSLLELEQHQTLLIEDQERKLLVLQLLAVLCEKMSEQIFTHITQVVDFVAATLQRACAGLAHEAESTVGSQTLSMAMGLVAAMLGGAVQKPFVGAALKSSDFVVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFSTEAVSTAAQSTLNKKDPEQKIKEQRQTSYDASTEGTQNRPEQEQ------------NPLRTGQGSSEPCTATSQPPGNITTEQFREVLLSACDPQVPTRAAALRTLSRWVEQREGRALEEQKKLLQIFLENLEHEDSFVYLSAIQGVALLSDVYPEEILVDLLARYDSSKDKHTPETRMKVGEVLMRIVRALGDMVS-KYREPLIHTFLRGVKDPDG-----AHRASSLSNLGELCQRLDFLLGPVVHEVTICLTAVAKTDTDVQVRRAAVHVVVLLLRGLS--QKATEMPVQLTTALRVVGTSLFALVVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRRMRRAGRPLKLHCSQRRRSVALCIAAYQEDPEYLRKCLRSAQRIAFPNLKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMERVRAVVWASTFSCIMQKWGGKREVMYTAFKALGNSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYCQDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCGKKPEQYSLAFAEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3S2-1", "uniprot_id": "TNG6_MOUSE", "id": "Q8C3S2-1", "name": "Transport and Golgi organization protein 6 homolog", "aln": "MAASGPAAAAPSGVLVTCGLEQVLEALKLLLSPGGSGSSSLQNTKHDVLLQTLKSNLSALEAKFLKDAQWKKLKALRDELADKAEWPQSSEDITWSFTSQTLLLLLCLKEVLARLVADFNPGKPNPRTPEAAPALSPDTLSVSQQKTFQSVLQFVVTLGVCPYLIPGVGVPLRDRTEFGAVVQDVVRLEAAPHATRRLYICCRVLLDLAQHASLGSLIFCRHFGDIAAGLCQLGFCPTKRKPPGPVEEVLTEEERTLSRRALRDILDQVYQPLAVRELLTLQGGPRQPCTDVKTQLRCRAQAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEATAADWRKCDLIAKILASCPQQSLSPESYYKDICPQILDLFHLQDKLTARQFQRVATTTFITLSRERPELAAKYLLQPMLAPLQRCLSTAEIPESDMVPGAILVTEEELSRCVEDVFKVYVVANEPVPVLLDSLLPLLRVFFSLYCFTQQSVSHIRSLCQEILLWILVKLERKKAIASLKGFSGLDKTVPTLHPQCQFRAATHGGIVITAKEAISD-DEDEALYQKVSSEQSQVEHLGDLLLHCQQCGLAGDFFIFCLKELSHLLEDREAEFTPKPSCYASLLELEHHQTLLIEDQERKLQVLQLLAVLCEKMSEQIFTHVTQVVDFVAATLQRACAGLAHEAESAVGSQTLSMSMGLVAVMLGGAVQ-------LKSSDFAVLKQLLPLLERVSNTYPDPVIQELAADLRITISTHGAFSTDAVSTAAQSTLNQKDPGQKIEEQRQTSPDISTEGAQKPP-------------------RTGQGSSGPCTATSQPPGSITTQQFREVLLSACDPEVPTRAAALRTLARWVEQREARALEEQKKLLQIFLENLEHEDSFVYLSAIQGIALLSDVYPEEILVDLLAKYDSGKDKHTPETRMKVGEVLMRVVRALGDMVS-KYREPLIHTFLRGVRDPDA-----AHRASSLANLGELCQCLHFLLGPVVHEVTACLIAVAKTDNDVQVRRAAVHVVVLLLRGLS--QKATEV----------------------------------------------------LSDVLRDLYHLLKHVVRLEPDDVAKLHAQ----------LALEELDEIMRNFLFPPQKLEK---KIVVLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0B7-1", "uniprot_id": "TNG6_HUMAN", "id": "Q9C0B7-1", "name": "Transport and Golgi organization protein 6 homolog", "aln": "MAAR---QAVGSGAQETCGLDRILEALKLLLSPGGSGSSSLQVTKHDVLLATLKSNLSALEDKFLKDPQWKNLKLLRDEIADKAEWPQNSVDVTWSFTSQTLLLLLCLKETMIRLAANFNPGKPNPRTPEVAPALSPDALSISQQKTVQFVLQFVVTLGICPYLMPGVGVPLRYRTEFGAVVQDVVCFDAAPDATRRLYTSCKALLNVAQHTSLGSLIFCHHFGDIAAGLCQLGFCPTKRKLLTPAEEVLTEEERTLSRGALRDMLDQVYQPLAVRELLILQGGPPQSCTDVKTQMRCR--APAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEVTAADWKKCDLIAKILASCPQQSLSPENYYRDICPQVLDLFHFQDKLTARQFQRVATTTFITLSRERPHLAAKYLLQPVLAPLHRCLNTAELSESDMVPGTILVTEEELSRCIEDVFKVYVVGNEPLTVLMDSLLPVLGVLFLLYCFTKQSVSHIRSLCQEILLWILGKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVATQGGIMITIKEAISDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQ-------LKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVS-KYREPLIHTFLRGVRDPDG-----AHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLS--QKATEV----------------------------------------------------LSAVLKDLYHLLKHVVCLEPDDVAKLHAQ----------LALEELDDIMKNFLFPPQKLEK---KIMVLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12751-1", "uniprot_id": "RTP1_YEAST", "id": "Q12751-1", "name": "RNA polymerase II assembly factor RTP1", "aln": "----------------------------------MNEDKEQKINIHDILNTRPKLTKKTALDVFFEDLDDNVITPINEYVLDSGSSSSSSIYQALKCSNNNEFVAVLLQKFQNLHIHVLEQQR---RLIESKSDLLP--ISLHDMKYVDELINLLIIHGIDANLSPTMKIPFDSK----RINTFKKGQKSAEYETPRWHTINNDTLSQVITVFYN-VLTSERSSDYLREIISKGSAYANILLGLIVLHLQLPNRYSSQMITNLEDTQETYTLFGVYTLLVETIQDEKVREPILSKLTT-----LTLRRPENGLISLIDFVLGVRDAEDIDIEKFNRIYQILMSKPKTMTNLQYLTELFKQIYDG---LTFVNRPILVTCLNGLILKFYLRNKRIVNDFLFKKVRSIIFNSP-----LTDHTAKELNDVINVLISLSKNSSSDLLN-DLVTSCPDEDGTTPGQFFLYVWIYALFLKKNQKLDPLEINKLSISDNKSTDSIHFPEQSSSKYYEVVLSLLKSLIVITEN-FQYLNVLSLNLLNFEHEKWKYLIDLDTQLPYISVKNTDMAELFFEKGSKNSQISEFLQDMDLSIELFMEFLVLLNDEEQSKTLFLDILKRWVHHTKKSEKRSSDNHSGMPSVTDNALILMDLKLLECMNNRFKTKIVNKPKDVLIVIDQLID-----VVQEKDETIQEVEADSDDEVEEGEETEELD---------PNENSSYKIILQLLSTVLSESSSSILLQNSYILKSISRKLQSFNTNASEIDALLASIDNILINGHTTERNDNIEIEMD----------------------------------------------EERLDKAITSLHDPLVPIKSYGLTELRHLAEKKS--PVISLEKVLQIHLDYLKNMDPFIYLNVIKGLTTLCELEPETILPLLAEFYANKKKKNRLDDVLKVGEVFINYIQRQNELFQGKLAYLIIDTCLSIVRPNDSKPLDNRWRMSSMSILGMCLQINARGVSDRIRDMLDCVFGILQLE-QPQNHLKDKDDSFLMRRSAV--HLIHDL-------------------------------------------------------LYSTGFDLLPFEYNYDKLKTLLSYVR-----------DQDEDYMVCEQIDKLLTVLDSL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJ29-1", "uniprot_id": "TNG6_DROME", "id": "Q9VJ29-1", "name": "Transport and Golgi organization protein 6", "aln": "---------------------------------------MINTAKYFALLESLR---------------------FSKALANTANNSGTAEALEINLRILEKYAKLEIGQQLHELCLEYQLTDDHESSIDPDSDRTICYIIRLQHVLHSIMRNINFHSDAKEDLISVAHLKLCIQASQELSYYSLRCQLHEDFYKSPIFCEAQGKIKANFSLMLLSIQFFINLLHIRQYHIANSMELVQRDLLAAIVSLRVQQDSPLLDKAIAYLWQYESKADFFRNILLFKATTLCP----------------TLAQLLHRQLLGKLHLPQGFASLVEALHQNPNVNSS------------RNAEIVASIVARKGFSQLAQEKMVLQVLEYCKFYLQNADKMCAGVLSLRRLYDLS-----------DTNQKLIKEILFKHWETLCNPE-DIINGLILMDHQELCNRILLWQHLFCSSTVACLP-SNLLVPYLPLLLQLYDGLPMELPASSQISAIILRCLDNREMKNELPAILQKLFKWEIEK-------EPPWKCLNPRIIILPSMNTTQIQVKVAHKDHLADHDMGRILPGLLTSSSHHSLTCKVFLSLLGFIAKQINDKSSASVDFISSEAELKDFLHSKYQLKLD----LLIALNQMVAHQPLRAQLSQHTKELLHILKDLLVHR----SREQD----------------------------------TTDQILLLVLNLLQEILEGSENIQLSEACKELKEQLHLLGTRSSNPLIQQSVKSLLTIIHGAWRPSE-----------------------------------------------------AVKIQPFQRARSLIEEKQSHMQVYGIQMMIDLLKKRDPATLAQGQLIIALALTTLKDKESYTFLNCVRLFVSLVHVMESDVLDKLSDEYLS--ETAHLDYRLVVGEAILKVAQELGPLCF-RYKAVLLNCFMYGSRSPVH-----EFRMSAFANLAQLCRLLAFQVQNFFHELLQLVNSELTTGGYVPSKRAAVLVLAELLNGMENLLDYQ--------------------------------------------------------EMLLPIYRLLKAIEADESCDPQMRQHAAN---------GLKILNKKCTKLIQSALEEKSLQKQIKVLGIKDDDSPQRRNRHILELN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : : . : :... . .: . : : : : : . : : . : :: . . * . : : : . . . :. : . . . .: : : . : : . :* * : : : : : ::. .* : . : :* . : : . : : : .. *:: :: : :: : * * : : . . . :. . : : . : . . :.:. : : . : .:: : . . : . * : : :: : .::: .: : :: : . :* **. : . . : : . *: : ::. : : : : : .. : : .: : :::. .: : :: : * *:. :.: :*. :: .. * .: . :* * * . .. : : ***.::. : . : : ::. : : * *::: *. : : .::: : . : : .. : : :* . : ", "identical_positions": 28, "similar_positions": 215, "identity": "1.74%" }, { "cls_id": "homologset.agr.MGI:2142792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZJ7-1", "uniprot_id": "DCNL2_MOUSE", "id": "Q8BZJ7-1", "name": "DCN1-like protein 2", "aln": "----------------------------------------MHKLKSA-QKDKVRQFMACTQASERTAIYCLTQNEWKLDEATDSFFQNPE-AFHRESMKSSVDQKKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISVLVIAWKF-RAATQCEFSKKEFVDGMTELGCDSTERLKALLPRLEQELKDPAK-FKDLYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRF------KFLDLWNTFLLEHHKRSIPRDTWNLLLDFGN---MIADDLSNYDEEGAWPVLIDDFVEYAR------------------PVVTGGRRSPF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0U1RRP2-1", "uniprot_id": "A0A0U1RRP2_RAT", "id": "A0A0U1RRP2-1", "name": "DCN1-like protein", "aln": "----------------------------------------MHKLKSA-QKDKVRQFMACTQASEKTAIYCLTQNEWKLDEATDSFFQNPE-AFHRESMKSSVDQKKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISVLVIAWRF-RAATQCEFSKKEFVDGMTELGCDSTERLKALLPKLEQELKDSAK-FKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRF------KFLDLWNTFLLEHHKRSIPRDTWNLLLDFGN---MIADDLSNYDEEGAWPVLIDDFVEYAR------------------PVVTGGRRGPL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PH85-1", "uniprot_id": "DCNL2_HUMAN", "id": "Q6PH85-1", "name": "DCN1-like protein 2", "aln": "----------------------------------------MHKLKSS-QKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPD-SLHRESMRNAVDKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKF-RAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKDTAK-FKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRF------KFLDLWNTFLMEHHKRSIPRDTWNLLLDFGN---MIADDMSNYDEEGAWPVLIDDFVEYAR------------------PVVTGGKRSLF---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GD41-1", "uniprot_id": "A0AC58GD41_DANRE", "id": "A0AC58GD41-1", "name": "DCN1-like protein", "aln": "MCVIFSLCMFVCVSFCLYTVLNVFLRLSEFMSEGISFVSTQHKLKSS-QKDKVRQFMSFTQAGEKTAVYCLTQNDWKLEVATDNYFQNPD-LYHKESMKSSVDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLNLDPASISVLVVAWKF-RAATQCEFSKKEFIDGMTELGCDSPEKLRALLPRLEQDLKDSGK-FKDFYQFTFNFAKNPGQKGLDLEMAVAYWNLVLAGRF------KFLDLWNRFLLEHHKRSIPKDTWNLLLDFGN---MIADDMSNYDEEGAWPVLIDDFVEYAR------------------PIVTGSKRKTV---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N010-1", "uniprot_id": "A0A8M1N010_DANRE", "id": "A0A8M1N010-1", "name": "DCN1-like protein", "aln": "-------------------------------------------------------------------------------------------------MKTAVDRRKLDLLYSRYKDPQDENKIGVDGIQQFCDDLMLDPASVSVLIVAWKF-RAATQCEFSRQEFLDGMTDLGCDSPEKLKSLLPRLEQELKDSGK-FRDFYRFTFSFAKSPGQKCLDLEMAVAYWNLILSGRF------KFLGLWNTFLLEHHKKSIPKDTWNLLLDFGN---MIADDMSNYDEEGAWPVLIDDFVEFAR------------------PIVTAENLQTL---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUQ8-1", "uniprot_id": "DCNL1_DROME", "id": "Q9VUQ8-1", "name": "DCN1-like protein 1", "aln": "----------------------------------------MNKLKSSTHRDKVKKFISLTHTGEQTAIFCLQQNDWKFELASDNYFQNPE-YYYRE-----LDRKRIEQLFMRYRDPSDPLKIGSQGVIHFLEDLDLKPDSKLVLIIAWKF-HAEVQCEFSRDEFINGMCDLGIDSIDKLKTKLPILEQELNDAGK-FKDFYHFTFNYAKDPGQKGIDLEMAIAYWCIVLSGRF------KFLDIWCQFLEEKHKRAISRDTWNLLLDFAT---NIDDRMSNYDSEGAWPVLIDDFVEWCQENDHLKEDSSPASGYQQQSSASSSSQKNISSAYQTSHSTNMNYG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12395-1", "uniprot_id": "DCN1_YEAST", "id": "Q12395-1", "name": "Defective in cullin neddylation protein 1", "aln": "-----------------------------------MSNNKIKRKDASPEQEAIESFTSLTKCDPKVSRKYLQRNHWNINYALNDYYDKEIGTFTDEVSTVAHPPVYPKELTQVFEHYINNNLFDIDSLVKFIEELGYNLEDLATLCLAHLLGYKKLEEPLKREDFLSTWFMQGCSTISDMQECIKTLDVKLHEDLQYFTQIYNYAFNLILDPNRKDIDTDEGIQYWKLFFQPEYPVRMEPDLLEAWFRFLRDEGKTTISKDTWRMLLLFFKRYPTIQKIISDYDETAAWPFIIDEFYECLQ------------------------DQQ-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :.. : :. :.: :* ::* . . .* :* : : :.:.:*:. * .: . :: : *: .*:: : * ::*.::*. .*.:* :* : .: ** :.: .: .:* * ** :. * :*.:***.:** * . * . :*:**. .***.:**:* * : ", "identical_positions": 40, "similar_positions": 74, "identity": "11.59%" }, { "cls_id": "homologset.agr.MGI:2142808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZM3-1", "uniprot_id": "D3ZZM3_RAT", "id": "D3ZZM3-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "MDSPKGCRASAEGTSRARKRRVGTKMADVESPPKLSGAPPPPEGVGGGHCSEISTELIRSLTELQELEAVYERLCGEEKVVEKELDALLEQ-QNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHIHRYLCLDKS---VIELSRQGKEGSMIDAN--LKLLQEAEQRLKAIVAEKFAAATKEGDLPQVERFFKIFPLLGLHEDGLSKFSEYLCKQVASKAEENLLLVLGSDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGR--LFTLIKYLQVECDTQVEKVVNKFIKQRDYHQQFRLVQSNLMR----------------------NSATEKIEPRELDPVLTEVTLMNARSELYLRFLRKRISADFEVGDSMASEEVKQEHQKCLDKLLNN-------CLLSCTMQELVGFYITMEEYFMRETVNKAVALDTYE-KGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINLATRELEADFRDVLCN------KLRMGFPATTLQDIQRGVTSAVNIMHSSLQQGKFD-------------------------TKGIESTDEAKLSFLVTLNNVEVCSENISTLK--KTLE-----------------------------------------------------------------------EEFNDYEAN---------------------DPWVQQFILSLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLER-VTEILDYWGA--NSGPLTWRLTPAEVRQVLALRIDFRNEDIKRLRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1U1-1", "uniprot_id": "COG4_MOUSE", "id": "Q8R1U1-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------MAEVESPLKLSGAPPPPEGVGGGHCSEISTELIRSLTELQELEAVYERLCGEEKAVEKELDALLEQ-QNTIESKMVTLHRMGPSLQLIEGDAKQLAGMITFTCSLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRNEDYEQAAAHIHRYLCLDKS---VIELSRQGKEGSMIDAN--LKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEDGLSKFSEYLCKQVASKAEENLLLVLGSDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGR--LFTLIKYLQVECDTQVEKVVNKFIKQRDYHQQFRLVQSNLMR----------------------NSATEKIEPRELDPVLTEVTLMNARSELYLRFLRKRISADFEVGDSMASEEVKQEHQKCLDKLLNN-------CLLSCTMQELIGFYITMEEYFMRETVNKAVALDTYE-KGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINLATRELEADFRDVLCN------KLRMGFPATTLQDIQRGVTSAVNIMHSSLQQGKFD-------------------------TKGIESTDEAKLSFLVTLNNVEVCSENISTLK--KTLESDCTKLFSQGIGGEQAQAKFDSCLSDL-AAVSNKFRDLLQEGLAELNSSAVKPQVQPWINTFLSVSHSIEEEEFNDYEAN---------------------DPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLER-VTEILDYWGA--NSGPLTWRLTPAEVRQVLALRIDFRNEDIKRLRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9E3-1", "uniprot_id": "COG4_HUMAN", "id": "Q9H9E3-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------MADLDSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALLEQ-QNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHTHRYLCLDKS---VIELSRQGKEGSMIDAN--LKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGR--LYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMR----------------------NSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNN-------CLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYE-KGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCN------KLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFD-------------------------TKGIESTDEAKMSFLVTLNNVEVCSENISTLK--KTLESDCTKLFSQGIGGEQAQAKFDSCLSDL-AAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEAN---------------------DPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLER-VTEILDYWGP--NSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q29RB1-1", "uniprot_id": "COG4_DANRE", "id": "Q29RB1-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------MEEAASPARRRGGPAG--------VSAVQTDTIEALTELEDLERVYAQLCAEEAEVQVELDALVGQ-QNNIETKMLSLQRMGPNLQLIEGDAVQLSGMINFTCSLAENVSSKVRQLDLTKKRLYQAIQRADDILDLKFCTDGVQTALRNQDYEQAAAHIHRYLSLDQS---VIELSKQGGEGSAVEAS--LALLQEAERNLKTLVTTRLEEAVATGDLPQVERFFKILPLLGLHEQGLARFAQYLCSQLASKAEENLILAVGSDLGERRAPVIFADTLTLLLEGIARIVETHQPIVETYYGPGR--LHTLLAHLQKECDKQAQKIVDKFIQQRDYNNKFQVVQSNMMR----------------------GMTTDKIEPRDLDPVLCEVTLMNSRAELYFRFLRRRIVADFEVADAMADEAVIQEHQQSLEQLLKN-------CQLSRTMQELIGYYIPMEEYYMRESVNKAVAMDTAE-VGQLSSSVVDDVFYIVKKCISRALTSSSSDCVCAMINHATSVLETDFREVLVC------KLRAGYPVSALQDLQRGVSSAVSLMQSSLQQGKITNLT---------------------QTLGIESQEQAKSAYLVTLNNVEVCSENISTLK--KNLESDCAKLFSQGASSDHAKEKIDSCLSDL-VNTSSKFKDLLQEGLQELNNTAIRPQVKPWISSFLSVSHNIEEEEFSEYEAN---------------------DPFVQQLIVQLEQLMAEFKVGLSPVIYDTLTSLMTSLIAMEMEKTVFKCTFSRLGGLQFDKELRALVAYLSSVTSWTIRDKFARLTQMATILNLER-VSEILDYWGP--NSGPLTWRLTPAEVRQVLALRVDFRSEDIKRLRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95TN4-1", "uniprot_id": "COG4_DROME", "id": "Q95TN4-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------------------------------MSVLEQLGALDIGTNEQVDETLQRIADEEAKVNEKLESLLAK-QCQIEAKMSGIGRSLSLLHTVDSDSNKLNDQIVNTAQLAESVSAKVRRLDLARCRASECQQRVHDLIDLHLCSQGVVKAIGEEDYEKSATHIARFLAMDQQ---LLRRTADDVQGSITSVSDAVKTLEDATEKTRVLIAKRFDEAVKADDLASVERFFKIFPLVGCHRTGIEKFSLYICQKLANKAQKELRNAQDIAKAESRLQLAYADRLTAILENFARVVEVNQPIIEAFYGQASSSLIDMVSILQHECDTEVKNLLMEFNKNRQIQYRSKQVNESTQRSAGGGNLGSNSIQALGHYRKPSGGSVDKLNPKEIDAIIAEITVMHARVELYFRFMRRRLQVHVET---CVPEKEQFDIMERYEKIMKN-------SDLRRQMQEILSTYLLLERYFMEESVLKAIGLDTYE-SGQQCSSMVDDVFFILRKSIRRALTTQSINGTCAVINNVAACLDGDFVNALKA------PLKSGYPSGYID-----LAQAYNAIQTSLQQGKLH----------------------------SSDADRGRANFLVQLNNADISTEYIETLC--QTMEQEIAGTFPQTTQVER--QMLDSCLTEL-KAVRDALKATVDFGMQQLRSSVIKPRLNPWINQFLNYSHNLNEEELAAYEAG---------------------ETFVQFFIVQLDGLLNSFKNSLSPRNYDALVSILATEVTIQLERAIKKISFNRLGGLVLDQEVRALGSYLTGATSWSVRDKMTRISQIATLLNLDK-ITELSEYWNPENNKEMSSWHLTPNEVRTFLTLRNDFRIEDIKRLQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06096-1", "uniprot_id": "COG4_YEAST", "id": "Q06096-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "----------------------------MEGQKSNASWESSIIEGQLSKNLARYTLLLDKLSTLSQIDKLSEVIANDYAKQSKQLNAFVQQSQSSLNKESRKLELQRTNLTTTLTQFHETVATISSSNARAKAIHDDIETVDQERALVNKTLQFVKDVRTLKNNISLAHSALETKDYLVAATAINEIRSLPDKKLIVSEFAKKVVPSSEIPEE-PAILIKNWCKELTSLFQEQFMEATRTQDIKELTLMFKMFPMIGQDVLGLDLYSKYVCDIIADESRK---IMSNSMENSTKFQGFFSQVLLHLFKIVSTIINDHSKVIATCYGKKH--MVHVMEKVEKEADLQASLILDIFMETRKIERTIHDINEWEHSQKNEDVNIDSNQSDIETDG--ETEKSSIISIHDLALLIMEFSQILQNWSMYSRFYSVKWNEFSDLHPHVLQPPPPIADGKFALKLKQDKVFDEFQVFVLNHLQRSFRNSISLEELPSLNDLITAVPLNDHDNISYPVTSVLDDLILLVRKNLISVVNTGQFKLLASFLNELVKFFQNRFLVKFMQNKFKLLQSKLASNVSLKRYIPKGEEQSATSRSVSPPANKFSPLSRFTFRGAAASALTNIQSNLQAVVAEDEDSILALHHYLIYLNTLYLSKVYVHRLLSIEILEDDSQRILRDNFPFDNDAAQLQNLIINSEKLVLEQTDKLSKWAVKYLFQNILQNRVRNLLGTVFVNSASSNSSTSNQKNVSRDYSAGSNQKNYITSIEDFEDLSQINSFNSKWNQLIIPYKNILHNEAYAELLSVIVDYIVTTLEQRIWTLEFNELGVTKLDRELSLFIGNMCGLN-YNLREKFLKLTQIVLLLGLDDDNFDLTTGDIKDDFNGTFDWVINSQERIKARNMKIDRTQ--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .::: :. : . :*:::: : * :: : : . * : : * : *: : .:. :* : : * ..*: *: . . .*: :** :*: . .: .. : . : . .* . ::: .. :. :: *. *: .: :**::*::* . *: :: *:*. :*.::.: . . : ::: * ::: .: ::: :. :: : ** : :: :: *.* :.. :: * : *. . : ::. . :. ::: :: *.: : . .:* ** : : : :: :: : :*. . : :*. : : .*: :: : . :*::**:: :::* : .:.: . . .:.:* . :: * : : . .: . * .*: .. . :*: **. :.. : * : :* . :.. . :: : . : : :* * * * .::. :. :*: : . *..** :*:*: : . : . :.:*:*: :::*:. :*.*: :: . * :.. * :: * ", "identical_positions": 69, "similar_positions": 250, "identity": "7.62%" }, { "cls_id": "homologset.agr.MGI:2142810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQB6-1", "uniprot_id": "VIP2_MOUSE", "id": "Q6ZQB6-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2", "aln": "---------------------------------------------------------------------------------------------------------------MSNSRKMSEPPRFFVGPEDAE----INPG---NYRRFFHHAEEEEEEED--------------------ESPPERQIVVGICSMAKKSKSKPMKEILERISLFKYITVVVFEEEIILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPFVINDLNMQYLIQDRRDVYSILQAEGILLPRYAILNRDPNNPKECNLIE--------------------GEDHVEVNGEVFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESNVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSIPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSGKLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKSKLEQLKTVLEMYGHFSGINRKVQLTYLPHGCPKTSSEEED----NRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISVIKSMHLIKNPVKTCDKVYSLIQSLTSQIRYRMEDPKSADIQLYHSETLELMLRRWSKLEKDFKTKNGRYDISKIPDIYDCIKYDVQHNG-SLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCTPLVRKIRSDLQR---TQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGALCDDSKDEQWKR---AMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGCEEDKNLPSGYGYRPASRENEG----------------RRSLKTD-DDEPHTSKRDEV------------------DRAVMLFKPLVSEPIHIHRKSPLPRSRKITAN---------------------------------------------------------------EVVSENANYLRTPRNLVEQKQ-----------NPTVG----------------------------------------------------------------------------------------------------------------------------FELYSMVPSICP-----------------------------------------------LETLHN----------------------------------------------------------ALFLKQVDDFLASIASPSTE-----------------------------------------VLRKVPEMS-------------------------SMAT-------------------------------RSSPGMRRKISLNTYTPTKILPTPP---------AALKSSK--------------------------ASSKAAAGGPSQAMAPHTSSRKKS--------INSKTEGHEP----------------------KKSTGKKR----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LQY2-1", "uniprot_id": "A0ABK0LQY2_RAT", "id": "A0ABK0LQY2-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "---------------------------------------------------------------------------------------------------------------------MSEAPRFFVGPEDAE----INAG---NYRRFFHHADEEEEEEE--------------------ESPPERQIVVGICSMAKKSKSKPMKEILERISLFKYITVVVFEEDVILNEPVGDWPLCDCLISFHSKGFPLDKAVAYAKLRNPFVINDLNMQYHIQDRRDVYSILQAEGILLPRYAILNRDPNNPKECSLIE--------------------GEDHVEVNGEVFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSIPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSGKLKLKKPKQLQAILDIARQLLMELGQNNDSDIEENKSKLEQLKTVLEMYGHFSGINRKVQLTYLPHGCPKTSSEEED----NRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISVIKSMHLIKNPVKTCDKVYSLIQSLTSQIRHRMEDPKSADIQLYHSETLELMLRRWSKLEKDFKTKNGRYDISKIPDIYDCIKYDVQHNG-SLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCTPLVRKIRSDLQR---TQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGALCDESKDEQWKR---AMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGCEEDKNLPSGYGYRPASRENEG----------------RRSLRAD-DDEPHTSRRDEV------------------DRAVMLFKPLVSEPIHIHRKSPLPRSRKMTSNEEETPLSVSSPEGTGTWLHYTS-----GVGTGRRRRRSGEQITSSPVSPKSLAFTSSIFGSWQQVVSENTNYLRAPRALVEQKQ-----------NPTVGSHCAGLFSTSVLGGSSSAPNLQDYARTHRKKL----------------------------------------------------TSSGCIDDATRGSAVKRFSISFARHPT-----------NGFELYSMVPSICP-----------------------------------------------LETLHN----------------------------------------------------------ALFLKQVDDFLASIASPSTE-----------------------------------------VLRKVPEMS-------------------------SVAS-------------------------------RSSPGIRRKISLNTYTPTKILPTPP---------AAVKSTK--------------------------ASSKAAAGGPSLAMASHTSSRKKS--------LSSKTEGHEP----------------------KKSTGKKR----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43314-1", "uniprot_id": "VIP2_HUMAN", "id": "O43314-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2", "aln": "---------------------------------------------------------------------------------------------------------------------MSEAPRFFVGPEDTE----INPG---NYRHFFHHADEDDEEED--------------------DSPPERQIVVGICSMAKKSKSKPMKEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPFVINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIE--------------------GEDHVEVNGEVFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESNVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSIPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSGKLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQLTYLPHGCPKTSSEEED----SRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPVKTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDISKIPDIYDCIKYDVQHNG-SLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCTPLVRKIRSDLQR---TQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGALCNESKDEQWKR---AMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGCEEDKNLPSGYGYRPASRENEG----------------RRPFKIDNDDEPHTSKRDEV------------------DRAVILFKPMVSEPIHIHRKSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTS-----GVGTGRRRRRSGEQITSSPVSPKSLAFTSSIFGSWQQVVSENANYLRTPRTLVEQKQ-----------NPTVGSHCAGLFSTSVLGGSSSAPNLQDYARTHRKKL----------------------------------------------------TSSGCIDDATRGSAVKRFSISFARHPT-----------NGFELYSMVPSICP-----------------------------------------------LETLHN----------------------------------------------------------ALSLKQVDEFLASIASPSSD-----------------------------------------VPRKTAEIS-------------------------STAL-------------------------------RSSPIMRKKVSLNTYTPAKILPTPP---------ATLKSTK--------------------------ASSKPATSGPSSAVVPNTSSRKKN--------ITSKTETHEH----------------------KKNTGKKK----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCT9-1", "uniprot_id": "A0A8M3BCT9_DANRE", "id": "A0A8M3BCT9-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "----------------------------------------------------------------------------------------------------------------MSVHEDLDHPRFFVGADDGEGDELLDPGRVLGYDCLYENVEEEDEERDDAE----------------YDSPPERQIVVGICAMSKKSKSKPMKEILERLSLFKYITVVTFEEEVILNETVENWPLCDCLISFHSKGFPLDKAVAYEKLRNPFVINDLDLQYYIQDRREVYRILKDEGIQLPRFAVLNRDPARPEECNLVE--------------------GEDHVEVNGEIFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESNVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIIMRELAPQFQIPWSIPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQRFFDLFEKCEGYKSGKLKLKKPKQLQEVLDIARQLLVELGQNNDSEIEESKAKLEQLKTVLEMYGHFSGINRKVQLTYLPHGCPKTSSEEED----VRRDDPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQQKVKARLHEILQKDRDFAAEDYEKLAPTSSTSLVKSMQMIKNPVKTCDKVYSLIQNLTLQIRQRMEEPKSADIQLYHSETLELMLRRWSKLEKDFKMKNGRYNISKIPDIYDCIKYDVQHNS-SLKLDNTMEIYRLSKALADIVIPQEYGISQAEKLDIAKGYCTPLIRKIRSDLQR---TQDDDTVNKLHPVYSRGVMSPERHVRTRLYFTSESHVHSLLSILRYGALCDEAKDDQWKR---AMDYLKIVSELNYMTQIVIMLYEDPNKDPSSEDRFHVELHFSPGAKGCEEDKNLPSGFGYRPASRENEGP---------------KKKSNNDSDEEASGAKRDEP------------------DRALMMFRPMVSDPIYIHRKSPLPRSKKIGSVEEESPLSVSSPDSIGTWIHYTC-----GVGTGRRRRRSGDQITSSPVSPKSLAFTSSIFGSWQQVLSENNSHARPSRLHADHKL-----------TTGLGSHCAGLFSTMVLGGSSSAPNLQDYAHAHRKKL----------------------------------------------------TSSGFLDEATRGSAVKRFSISFARHPTN----VLSGLFSGFELYSMVPSICP-----------------------------------------------LETLHN----------------------------------------------------------SLSLKQVDDFLSAIAISHDS-----------------------------------------ILDISTSSP-------------------------AVPT-------------------------------KKAP-------LNTYTPAKVLPCPFTQSLGKRTCSPEKSAKDKDESPANKPKTLSKDVPDDGRTSEIAESKQLRPAPQISIIPPESTDKTQQQSTLSSVSSSGTPSHEAS-------------------VLKNPTNTMSGFNS------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR59-1", "uniprot_id": "VIP1_DROME", "id": "Q9VR59-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "----------------------------------------------------------------------------------------------------------------MSYTELESGYQDISQQHQQQNPHQSQPQQRVGFYLGLQDGNGDTDFGDSNDGMDSDTS---------TSSSNSKQVVVGICAMAKKTQSKPMKEILTRLGEFEFIKLVTFEENVILREPVQNWPTCDCLVSFHSKGFPLEKAIEYAQLRNPFVLNNLHMQYDIQDRRRVYAILEKEGIEIPRYAVLDRDSPDPKHHELIE--------------------SEDHVEVNGITFNKPFVEKPVSAEDHNIYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESRVRKTGSFIYEDFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVILNHSEKLISRKVCLAFKQTVCGFDLLRANGKSYVCDVNGFSFVKNSNKYYDDCAKILGNMILRELTPTLHIPWSVPFQLDDPPIVPTTFGKMMELRCVVAVIRHGDRTPKQKMKVEVRHPKFFEIFEKYDGYKLGHVKLKRPKQLQEILDIARFLLSEIHTKAHAEIEEKESKLEQLKNVLEMYGHFSGINRKVQMKYQPKGRPRGSSSDDTNLAADQPVEPSLVLILKWGGELTPAGRIQAEELGRIFRCMYPGGQGRSDYSGTQGLGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANTNGLLDNDCDS-SKYQNLAKGRLHELMQNDREFSKEDRELINPCNSKSITQALDFVKNPVDCCHHVHLLIRELLHIISIKKDDPKTKDAILYHGETWDLMRCRWEKIEKDFSTKSKLFDISKIPDIYDCIKYDLQHNQHTLQYDQAEELYIYAKNLADIVIPQEYGLTPQEKLAIGQGICSPLLRKIKGDLQRNIDEVEDEFMNRLNPHYSHGVASPQRHVRTRLYFTSESHVHSLLTVLRYGGLLNVVTDEQWRR---AMDYISMVSELNYMSQIVIMLYEDPTKDPTSEERFHVELHFSPGVN-CCVQKNLPPGPGFRPHSHGDNACNVSLQSSDESNPARIEEENDSNSGEEREGKKRGTSGQRSTDRSAERISPAFGFNRLELRSKQFKSKPIPIGAHHTVSGHEAMDLAKRLNEELASHQQQQNQQLRPISPDIRAVTPDCEPRSRSFEQRPTSGVCAKEPDSQVSVSVSASVSSANASTSSRRQRHSIAGQMSYMKMLGFGGFSKKMATSANSLFSTAVISGSSSAPNLRDMITVSSSGFGDVPPIRPLETLHNALSLRKLDSFLQDMILAQIFKTPTGSPPRGFSKNTLPAVSSMTLTASNQTEVVEHEPISTTVTPTFDRRGSESGSTADAHLRLLSESQCPNLDDSNTELRESLAGKMELWPQDIVKAAEDEELNLSELETKPSLDLTMEIMERGVAGIASIQPMNRDSDETMGGGVFLSVCEEQGSGSTCLTPVSFGMDLDLSMVANKGSITLSMEGFDDDEDATLSAATTPSLLADCEPRLESCYCCPSHAEAPPEVPSDDPRFGFALPVRVTQASPEHARPVRRAHDPVSPRIQKQISLFEGNAAMATGQEKTESSGSVGGGAILHASINLPAAGPHHLRQDARLRKFENLTQSTSNSNFPFESN----TLKRVPMQTTKDYDNVSHTQSCINLKSGSSGVLGGSPQRQRGSDGGGVGASGVPAESREPTRVHYGRMNSTCCSASASPSPSPGALIVKERFIEPPKRGVVRGYHGKTQSMDADFLFNEFLLLPAMAPAKISFDSSDIDQASDDDSPSSSKQRHA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06685-1", "uniprot_id": "VIP1_YEAST", "id": "Q06685-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "MSGIKKEPIESDEVPQQETKNNLPSAPSEMSPLFLNKNTQKAMQSIAPILEGFSPKTSASENMSLKLPPPGIQDDHSEENLTVHDTLQRTISTALGNGNNTNTVTTSGLKKADSESKSEADPEGLSNSNIVNDADNINSISKTGSPHLPQGTMDAEQTNMGTNSVPTSSASSRKSSTSHPKPRLPKVGKIGVCAMDAKVLSKPMRHILNRLIEHGEFETVIFGDKVILDERIENWPTCDFLISFFSSGFPLDKAIKYVKLRKPFIINDLIMQKILWDRRLCLQVLEAYNVPTPPRLEISRDGGPRANEELRAKLREHGVEVKPVEEPEWKMVDDDTLEVDGKTMTKPFVEKPVDGEDHNIYIYYHSKNGGGGRRLFRKVGNKSSEFDPTLVHPRTEGSYIYEQFMDTDNFEDVKAYTIGENFCHAETRKSPVVDGIVRRNTHGKEVRYITELSDEEKTIAGKVSKAFSQMICGFDLLRVSGKSYVIDVNGFSFVKDNKAYYDSCANILR-------STFIEAKKKMDMEKKNLPIIREEKEQKWVFKGLAIIIRHADRTPKQKFKHSFTSPIFISLLKGHK----EEVVIRNVNDLKIVLQALRIALDEKAGN--------PAKIKVLANALEKKLNFPGTKIQLKPVLN-----------------KENEVEKVQFILKWGGEPTHSAKYQATELGEQMRQDFD-----------------LLNKSILQNIKIFSSSERRVLHTAQYWTRALFGADELGS-------DEISIRKDLLDDSNAAKDLMDKVKKKLKPLLREGKEAPPQFAWPSKMPEPYLVIKRVVELMN-----------YHKKIMDNNFAKKDVNSMQTRWCTSEDPSLFKERWDKLFKEFNN-AEKVDPSKISELYDTMKYDALHNR-------QFLENIFDPGLPNEAIADELGSHSLVDRYPINVLAKNNFKIIDSHSMNNSGKNSSNSVGSLGWVLESGKTSTARNPKSSSQFDEPRFMQLRELYKLAKVLFDFICPKEYGISDAEKLDIGLLTSLPLAKQILNDIGDMKNRETPACVAYFTKESHIYTLLNIIYESGIPMRIARNALPELDYLS---------------QITFELYESTDASGQKSHSI-------------------RLKMSPGCHTQDPLDVQLDDRHYIS----------------------------------------------------------------------CIPKISLTKHLDMDYVQQKLR-----------------------------------------------------------------------------------------------------------------------------------------NKFTRVIMPPKFTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------VNITSPNLS---------------------------------------------------------------------------------FQKRKTRRKSVSVEK-------------------------------------------LKRPASSGSSSSTSVNKTLD-------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : :. . . : .. : :*:*:* * ****:.** *: . : * * :.:** * : :** ** *:**.*.****:**: * :**:**::*:* :* : *** :*: .: * :.** . .* .:* :**:* : ********..****:**** :. ***.:*****:*.:** :.* *. **:***:** **. ***.**:* ::.***:****.:** *.*::.***:** . *. ** *: **. **.* :*******..*:*** *********:. ***.**:** :. :. .: :: .: **: :: : :***.*******:* .. *:.::: . .: ::. ::*: :*: * * * : .*:: * ..** :*.* : ::: . .: ::****** * :.: ** ***. :* : *:.: :::**::*.* ** ** :::.*:. : : .. . . * .*.:: .. : .* :*: ::::.:: . : . : : : : * :. .: :: : .* .*: **.*: *:*. : ***.::** :*** ** *.: .*.:* * . : .. .: * .. . ..: :. * . * *. *: :: * . .:: * : .:: : ::..* .**: : : .:: .: :..: . :..:* . .. .. : . . : : * : ..*: : . .: : : : . * . * . .. .: . : ", "identical_positions": 235, "similar_positions": 299, "identity": "12.72%" }, { "cls_id": "homologset.agr.MGI:2142824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSC3-1", "uniprot_id": "NEK5_MOUSE", "id": "Q7TSC3-1", "name": "Serine/threonine-protein kinase Nek5", "aln": "MDNFHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTK----EKEASKNEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFLETLIARSLYPEVCSR--------------------------------------RIQSHAHMENMAIGPTACWRV-------------------------------------------------------------------SPWSAAYLQRKFEAQQYKLKVERQL---------------GLRPSSVEPHPNEGEKLQSHWEETKFQELQYRKNKMKDQEYWKQLEEIRQQYHNDMKEIKKKMGRELKR-----------------------------------------------------------------------------------VVKFEISLDKCISEEDTVQENEAVDKLNATLSFEDGTKFQEHRCK-EEHEDYTDRAFEELCGPEAEGFFQDVIAAENRRQWDAGAPHTLLRIMAMADVTSTCPTMPDDGQVIVMEGSVENGKQWWLDVPGTPCALAAECACSGSLSASKGETVMIK-PQLPKEDQEKVEIATGIMVDDEQLEPGSDEDDIKFEESEDELRSEIIESLEKLAASTEEAEQAPSSSKNAEEPGEKEKTNLPVKKLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJB7-1", "uniprot_id": "A0A8I6AJB7_RAT", "id": "A0A8I6AJB7-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDKFDLIKIIGEGTFGKVYLAKDKSESCHCVIKEISLTK----EKEASKNEVTLLAKMKHSNIVTFFSSFQENSRLFIVMEYCDGGDLMERIQRQRGVLFSEDQILCWFVQISLGLKHIHDKKVLHRDIKSQNIFLSKNGMVAKLGDFGTARTLNNSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELCTLKHPFESDNLHHLVLKICQGRVAPISPHFSLDLQSLIPQLFRVSPQDRPSINSLLKRPFLETLVARYLSPEIHSR--------------------------------------RIQSHARMENAAVGFTACWRG-------------------------------------------------------------------SPWSAAYLQRKSEARQYKLKVERQLDLVYSYDGPVQSMAQGLRPSSVEAHPNERENLQSHREETKFQELRYRKNKMNDQEYWKQLEEIRQQYHNDMKEIKKKMGRELKENAGLSHRTYLVKRSNLPSCPDA----------------------------------------------------PEDKVSKQRGVKFEISLDECISEEDTIQEDEVVERLSDTLSFEDGMKFQESKCRGEREEDYTDRAFEELCGSEAEGFFQDVTATENRRQWDAGAPQTLLQMMAAADITSTCPTMPDDGQVIVMDGSQENRKQWWQDVPGTPPALAIERACSGSLSAGKGETVMMINPQLPKEDEEEGEIAAGITVGDERLQRGSDGDVTKFEESEDELRSEIIESLEKLSASTEGREWDPSSSKNAEKPA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P3R8-1", "uniprot_id": "NEK5_HUMAN", "id": "Q6P3R8-1", "name": "Serine/threonine-protein kinase Nek5", "aln": "MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIPKYLTPEVIQEEFSHMLICRAGAPASRHAGKVVQKCKIQKVRFQGKCPPRSRISVPIKRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDYYYAQLDMLRRRAHKPSYHPIPQENTGVEDYGQETRHGPSPSQWPAEYLQRKFEAQQYKLKVEKQL---------------GLRPSSAEPNYNQRQELRSNGEEPRFQELPFRKNEMKEQEYWKQLEEIRQQYHNDMKEIRKKMGREPEENSKISHKTYLVKKSNLPVHQDASEGEAPVQMEFRSCCPGWSAMARSWLTATSASQDIEKDLKQMRLQNTKESKNPEQKYKAKKGVKFEINLDKCISDENILQEEEAMDIPNETLTFEDGMKFKEYECV-KEHGDYTDKAFEKLHCPEAGFSTQTVAAVGNRRQWDGGAPQTLLQMMAVADITSTCPTGPDSESVLSVSRQEGKTK-----DPYSPVLILM-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::.:** **:*:***.****.**:* *******.: * ******:** ** :*:*.***:**.*****.***************:**:*****:******* **************:*:******:****************** **.**:*****:** *************:**************************.:*:::*******.:.***** ** :*:***.***:***:****:.*:*******.*:.: * **: .. * : . ::. *: ** * *.* ***** **:*******:** ******.*.: *: ::*:*: **.:**** :***:*::*********************:****** :. *****.**:***:*: :**:*.:: . **:**** **:* .* :.. ****:***:* .** * * *. ******.***:***::** **:****** **. .*: :. . : * * :* : ", "identical_positions": 341, "similar_positions": 111, "identity": "40.79%" }, { "cls_id": "homologset.agr.MGI:2142841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1Q3-1", "uniprot_id": "A0A0G2K1Q3_RAT", "id": "A0A0G2K1Q3-1", "name": "Hexosyltransferase", "aln": "--MRRRPRLCRDAWLTLLLSAALGLLLYAQRDGVS----------PTTRA----------------------PPARGRQLPRPTPGRRALELPNTAHAAPPA--YEGETPVPPTPTDP-FDFRRYLRAKDQRRFPLLINQ-----------PRKCHSDGASGGSLDLLIAVKSVAADFERREAVRQTWGAEGRVQGAL-------VRRVFLLGVPKGAGSG-----GAGTRTHWRA---------------------LLEAESRAYADILLWAFEDTFFNLTLKEIHFLSWASAFCP-DVHFVFKGDADVFVHVRNLLQFLE--------------------------PRDPAQDLLAGDVIVQARPIRARASKYFIPQAVYGLPVYPAYAGGGGFVLSGATLHRLAHACTQVELFPIDDVFLG-MCLQRLRLTPEPHPAFRTFGISQPSAAPHLRTFDPCFYRELVVVHGLSAADIWLMWRLLHGPQGPVCAHPQPVATGPFQWNS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI16-1", "uniprot_id": "B3GN9_MOUSE", "id": "Q8VI16-1", "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9", "aln": "MRRRRRPRLCPDAWLTLLLSAALGLLLYAQRDVAS----------PTTR-----------------------PPARGPQLPRPTPSLRARELPNTARAAPLA--YEGDTPVPPTPTDP-FDFGGYLRAKDQRRFPLLINQ-----------RRKCRSDGASGGSPDLLIAVKSVAADFERREAVRQTWGAEGRVQGAL-------VRRVFLLGVPKGAGSG-----GAGTRSHWRT---------------------LLEAESRAYADILLWAFEDTFFNLTLKEIHFLSWASAFCP-DVHFVFKGDADVFVHVRNLLQFLE--------------------------LRDPAQDLLAGDVIVQARPIRARASKYFIPRAVYGLPVYPAYAGGGGFVLSGATLRRLADACSQVELFPIDDVFLG-MCLQRLRLTPEPHPAFRTFGISQPSAAPHLRTFDPCFYRELVVVHGLSAADIWLMWRLLHGPQGPVCAHPQPVATGPFQWNS---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX72-1", "uniprot_id": "B3GN9_HUMAN", "id": "Q6UX72-1", "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9", "aln": "--MRRRLRLRRDALLTLLLGASLGLLLYAQRDGAA----------PTASA----------------------PRGRGRAAPRPTPGPRAFQLP-DAGAAPPA--YEGDTPAPPTPTGP-FDFARYLRAKDQRRFPLLINQ-----------PHKCRGDGAPGGRPDLLIAVKSVAEDFERRQAVRQTWGAEGRVQGAL-------VRRVFLLGVPRGAGSGGADEVGEGARTHWRA---------------------LLRAESLAYADILLWAFDDTFFNLTLKEIHFLAWASAFCP-DVRFVFKGDADVFVNVGNLLEFLA--------------------------PRDPAQDLLAGDVIVHARPIRTRASKYYIPEAVYGLPAYPAYAGGGGFVLSGATLHRLAGACAQVELFPIDDVFLG-MCLQRLRLTPEPHPAFRTFGIPQPSAAPHLSTFDPCFYRELVVVHGLSAADIWLMWRLLHGPHGPACAHPQPVAAGPFQWDS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PD09-1", "uniprot_id": "A0A8M9PD09_DANRE", "id": "A0A8M9PD09-1", "name": "Hexosyltransferase", "aln": "---MRRVYLKGDVLCSLTLMLLLFLLLYAYQRVTPTWGTLHIEHGPTSSRTLLSGASMGQQTKLVPTKSLDIPPCQPEVQTKSKPQGQSKVKPQKARSKTKSKFQQASTTASLLPTQHSFDFADYLRKKDQRDFKMLIDQ-----------PTKCS---EPESAPYMLIAIKSVTTDFDKRQVVRRTWGREGVFQKNIN------IKRVFLLGVPQ----------NQSALPLWDK---------------------LLEYESHTFGDILLWDFEDTFFNLTLKEIHFLQWINVSCP-KTKFIFKGDADVYVNIDNILEMLE--------------------------SQEIDKDLFVGDIIVHAKPIRRRSSKYFVPEFIYGQGIYPSYAGGGGFVMSGHTALKLHLACKEVELFPIDDVFLG-MCLLRIGLQPTRHEGFRTFGIVKPSAAPHLQVFDPCFYRELMVVHSLTVPQIWLMWNLLHDPN-LRCHRSQDPTVFPFQWSEKIGKTARNKAEENLRNKDYGMKVFVEH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8R6-1", "uniprot_id": "A1Z8R6_DROME", "id": "A1Z8R6-1", "name": "Hexosyltransferase", "aln": "--MDRRWNPEKIEEQSSLLAAEYSSSSGAAASGSE-------DETVTTSG-----------------------ALRSKAKLRKRQLRNRMPLPRMLRRLGCYTLSAFLICGLLLVYLPLVYLDVHKRSAGLPDWTSETSRSIADYLDIGLSSGVIVPKDFCRNKTFLVIAVCTGVDNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLTASVRIVFIVGRQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFNTAVYFLKCDDDTFVNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLYGHQFCNVVPVSEVSSKWYMPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGLCAQKAKINRHHHPLFS-----------FAHSKQMCAFKGTITQHQLKDDSMVSAWNYVSNYSIKCPPPGRYFSQVRLRKRPIC-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : * * *: : : . * . : : * . : .: . ::**: : . :* :*..:*.*** .: :: :* :* . . :. ** : **: * *:: *****.: * . * . :.:* * *.:*:: *:*::* . .*:: *. : :. *: :**:::* :* ** * .*.*:::* . :* *. :. *. ::**:: :* : : * * . : * :: :. * *. .: *. : . : : :: ", "identical_positions": 62, "similar_positions": 100, "identity": "11.61%" }, { "cls_id": "homologset.agr.MGI:2142877", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0V4-1", "uniprot_id": "A0A8I6A0V4_RAT", "id": "A0A8I6A0V4-1", "name": "", "aln": "--KESQVKTQSNPATPAPTAQRKPGASWKQTLPPVKEEDPRVKCRDCGAFGHIARNRRCPIKRGHFLLVAQPLGGKKEKENTDPCR--------PKGLQKLSQAARQRCDEQQRKAPFQKFPTEL--------QWRNQQGTLAQPQMSIIPGYRKMSEPPVEMALGKPTGPEKP----ALQSLDGP--FILHSRQKEGHNMTVPGVAKPVFRQDGRKTVSENLLDQKVQDISHQH-PVAVPKRKSITELFHKESKTQGPSKK---MQPSKHPVIHQDRQNPKLSFWAPDEEMSQCPTQPRQNPLKKQRIDSTNAPEESHARTASKSTLDIQSYPIANRLELKDAGEMSKKITVQVPSTDQQQLHGRAALVSTRPCIE---------SGQALRMIFTKHSHNFWSSRFLTVPAPLPIEKQ-TPAFQSPSFPEEGEAAGSQVKLSVLYEDLQVSSSS-EDSDGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A4E2-1", "uniprot_id": "A2A4E2_MOUSE", "id": "A2A4E2-1", "name": "", "aln": "--MESQIKG--LPAVPAQTAQGEPRSSWEQTLPSLKKENHMVKCRNCGGFGHNVRSRMCPMKQGHVLLVSQPLGARKEKENGDPCR--------PHGLQKLSQDTRQRFDEQQRKAPFQKFPMKP--------QKGDQQVNLAQPRMPSIPGIRKRSASPVKTSLGKQMCPGKP----VLQCFDSS--YILHSRQKEGRRMAVAGVAKLVLRQDGRNSASEELLDQK--GTSCQH-PVAVPKSNASSELFHKEPKAQGPSRK---TQPSQHPVIHQNRQNPKLSFGAPGKEASWCPTQPSQNPLKKQRLNSTDAPEKSHARTGSKGTLDSQSPPIANRLGLKGANEMSKKITAQDPSTDQQQLYSRAALFATRPCIEFHRASAGRVADQALRMIFTRHGSNCWSSRFLSVPPPLPLEKQ-TPPSESPTFPEEGEVAGSQVKVSILYEDLQVSSSSSENSDGE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q658T7-1", "uniprot_id": "F90A2_HUMAN", "id": "Q658T7-1", "name": "Putative protein FAM90A2P", "aln": "MTARRDPKPGAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCRALGHTVRSTRCPMKCWKAALVPPTLGKKEGKENLKPWKPQVEANPGPLNKDKGEKEERPRQQDPQRKALLHIFSGKPPEKLLPNRKGSTESSVFLRVASRPMPVHTTSKRPCVDPELADRSATEMSGRGSVLASLSPLRKASLRSSSSLGPKERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSREGGCREVPQAASKTHGLLQAVRPQAQDKRPAVTQPGPPAATHSLGLGSNLSFRPGAKRPAQAPIQGCLNFPKKPRLGPFQIPESAIQGGELGALENLQPPPAATELGPSTSPQMGRRTPAQVPGVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENRRWSSSLLAAPSFHSPEKLGVFLAQSPHVSEKSEGPCVRVPPNVLYEDLQVSSSS-EDSDSDLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . * * * : :. *. .:*: :**::* .:** .*. **:* : **. .** :: *** .* : * . :* .: * * :: **** :: *. : : :. : : :* . . . *. *.. . . .* .:. *:* .. * . .*.* : : *: .* ** * * : **: : :. : : :.*. .:: **. .. *. ..:*** . :. : .* * * ** *:.. : **.: . : *. * *..* . : :*.:: ..* *..*:* :.*..* :::.* . *.**::* : . *** :*:.*. . ** . :** ..*:.* . :* .:*********** *:**.: ", "identical_positions": 106, "similar_positions": 142, "identity": "22.84%" }, { "cls_id": "homologset.agr.MGI:2142885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJA2-1", "uniprot_id": "COG8_MOUSE", "id": "Q9JJA2-1", "name": "Conserved oligomeric Golgi complex subunit 8", "aln": "----MAAALPLQPSTTASATTTATAVALGEVEDEGLLASLFRDRFPEAQWREKPDVGRYLRELSGSGLDRLRREPERLAEERAQRLQQTRDLAFAN-------YKTFIRGAECTERIHRLFGDVEASLGRLLDRLPRFQQSCRNFVKEAEEISSSRRMN----------------------------TLTLNRHTEILEILEIPQLMDTCVRNSYHEEALELAAYVRRLERKYSSIPVIQGIVNEVR-QSMQLMLSQLIQQLRTNIQLPACLRVIGYLRRMDVFT---EAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEACRVHLFDIITQYRAIFSDEDPLLP-----PAMGEYTVNEGAIFHGWVLQKISQFLQVLETDLYRGIGGRLDSLLGQCMYFGLSFSRVGADFRGQLAPVFQRVAISTFQKAVEEAVEKFQDEMTSYTLISTAAILGSSNTPATVPATQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALAQDVTGTLENALTKVTKTILAFHRAEEAVFSSGEHEIFVQFCTAFLEDLVPYLNRCLQVLFPPAQIAQTLGISPTQLSKHGNLGHVNISAIQEPLAFILPKRETVFCLDEQELGPDLVAPAPELPAEQRSMEPVTEKREPGEPLPQEPMEGEPLPAEPPSEGGAIGSVPCPQPGEQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MW5-1", "uniprot_id": "COG8_HUMAN", "id": "Q96MW5-1", "name": "Conserved oligomeric Golgi complex subunit 8", "aln": "----------MATAATIPSVATATAAALGEVEDEGLLASLFRDRFPEAQWRERPDVGRYLRELSGSGLERLRREPERLAEERAQLLQQTRDLAFAN-------YKTFIRGAECTERIHRLFGDVEASLGRLLDRLPSFQQSCRNFVKEAEEISSNRRMN----------------------------SLTLNRHTEILEILEIPQLMDTCVRNSYYEEALELAAYVRRLERKYSSIPVIQGIVNEVR-QSMQLMLSQLIQQLRTNIQLPACLRVIGYLRRMDVFT---EAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEASRVHLFDIITQYRAIFSDEDPLLP-----PAMGEHTVNESAIFHGWVLQKVSQFLQVLETDLYRGIGGHLDSLLGQCMYFGLSFSRVGADFRGQLAPVFQRVAISTFQKAIQETVEKFQEEMNSYMLISAPAILGTSNMPAAVPATQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALAQDVTGALEDALAKVTKIILAFHRAEEAAFSSGEQELFVQFCTVFLEDLVPYLNRCLQVLFPPAQIAQTLGIPPTQLSKYGNLGHVNIGAIQEPLAFILPKRETLFTLDDQALGPELTAPAPEPPAEEPRLEPAG---------PACPEGGR---AETQAEPPSVGP----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKH0-1", "uniprot_id": "COG8_DROME", "id": "Q9VKH0-1", "name": "Conserved oligomeric Golgi complex subunit 8", "aln": "----------------------MDFPDKMDLENERVLKLIFPDGVPDN-LRGNPELDNYLAKLGTCKVEQLKKEQTRLAEEARTILEQTQDLAISN-------YRTFITTAENSRSIFSEFLRSEQQLDTLVSKLPDLSVQCERFLQDSAELNEQRRLN----------------------------SITLQKNAQLLEVLELPQLMERCIREGRYEEALELAAYATRLGQHQGHIPVVTSIVRSVE-ALWHNMLVQLVAQLRTDLQLPKCLQIVGYLRRMQAFG---DNELRLKFLQARDAWLTSCLEAIPTADAQQHLSKTIEITRINLFNIITQYRAIFPEDEGTLKTQSSLRPLQGVSCNGDRLFQAWLHNKISDFLQTLERDLQLGVG-SVETVLGQCMYFGLSFSRVGADFRALMAPIFVGVIRRRFESSVEQVDEQFERELERFTLINKVALH--SHARKQVDPEQE-SYAPPEALLDFYPLAALCNGYLSALNELRLCAPLALATDVTRCLQHSLQQAAQRVLAFYRQEQQAFAGSEREAFVRLCSCLAYDLVPYIQRCIHGVFPPQSLTVHLGISLLQLEQQ-QLTYLQQTRILEPLKHLLPTK-ALVQPQDKVMEAKPSAGVP-VTAEG-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04632-1", "uniprot_id": "COG8_YEAST", "id": "Q04632-1", "name": "Conserved oligomeric Golgi complex subunit 8", "aln": "MELILNSLISDDLTEEQKRLSLDFLQDILQSNTKDYESYFSSRAVPGSITEDIAEIDAELSALDRKIRKTLLDNTSQIIGNILENDDRAQLDDIAKSLEQLWELDTNINKAADRNVTNDDINNESVSIDDFLEDDKEDNDTGRIMTTESNNLARKKKEDEFHKALSRLRNRISTKEDDKDDIRSDTLVTVLENLDSITDLMELPFLARTCIRTGHYQEAVMLYTHTTSLRSRFPGSTIVDEVCEKVLNEISTTMLSGLVKLLSTNVSVNSLKKILQYLNSIPPFDGKTNKSLLSVFLAMRYKFITDEIASYP---------LDVESSNESLIEMMVKRKIEVLREHVYMSLN---VFLKSFLYDTNDLEIPFPEELESTVLRINGTNEEKEIEEKEKETKKEEYQKQDSVANNEEDVTENKS---IEDVQEEVQGKVEGEDDGAERKTENEIENETVNKTEDKAEKEKEEEVNTKDNKAEKEEEEINKVEVTPEEPSKSIDNK-----AEKEEEEINKVEVTPEEPSKKIRTSKRENKIPTN----AVMLQFVDKCITYVLKDLTRGLNSIKLSDSVCLQLVYCSFRLCDLNRNYHHLFLKKINDTSLFTTEQLARAIDKRAELASKYIYS---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : .* . .::. * *. . * : :: : :::: ::: * * * . : . .:. ::. . . : :: :: .:: : .*:. .: :::*:* * *:* . ::**: * ::. * : .:: : ..* ** *: * *::.: ::: **. : * : .* ** * :: . : : * :* . *::::.: : . :. : : : . : : : * .*: : : . : *.:. *. : .: :: : : : . . : . :: : : :::: : :: : : :: : : * :: :::: :: : * :: : . .: * :* . . : : : . : : . : .. ", "identical_positions": 41, "similar_positions": 170, "identity": "5.96%" }, { "cls_id": "homologset.agr.MGI:2142888", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L8K2-1", "uniprot_id": "A0ABK0L8K2_RAT", "id": "A0ABK0L8K2-1", "name": "", "aln": "MRGGEELDGFEGEASSTSMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVAQVILALIAFICIET-IMECSPCEGLYFFEFVSCSAFVVTGVLLILFSLNLHMR-IPQINWSLTDLVNTGLSTFFFFIASIVLAALNHKTGAEIAAVIFGFLATAAYAVSTFLAVQKWRVSIRQQSANDYIRARTESRDVDGRPEIQRLDT--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJ61-1", "uniprot_id": "CKLF4_MOUSE", "id": "Q8CJ61-1", "name": "CKLF-like MARVEL transmembrane domain-containing protein 4", "aln": "MRGGEELDGFEGEASSTSMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVAQVILALIAFICIET-IMECSPCEGLYFFEFVSCSAFVVTGVLLILFSLNLHMR-IPQINWNLTDLVNTGLSTFFFFIASIVLAALNHKTGAEIAAVIFGFLATAAYAVSTFLAMQKWRVSVRQQSTNDYIRARTESRDVDSRPEIQRLDT--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZR5-1", "uniprot_id": "CKLF4_HUMAN", "id": "Q8IZR5-1", "name": "CKLF-like MARVEL transmembrane domain-containing protein 4", "aln": "MRSGEELDGFEGEASSTSMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVAQVILALIAFICIET-IMACSPCEGLYFFEFVSCSAFVVTGVLLIMFSLNLHMR-IPQINWNLTDLVNTGLSAFLFFIASIVLAALNHRAGAEIAAVIFGFLATAAYAVNTFLAVQKWRVSVRQQSTNDYIRARTESRDVDSRPEIQRLDTFSYSTNVTVRKKSPTNLLSLNHWQLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4B6-1", "uniprot_id": "Q9W4B6_DROME", "id": "Q9W4B6-1", "name": "MARVEL domain-containing protein", "aln": "-----------------MSLTGTQD-------------------YDRKYLLSMPGLCKLACLLCSFVGILCIICGPVRVSNFRGSFYLAVVTIG-FVATGCLLLARYLRLWQRQFCRCDPTLWSLAVHSSLALAYFTASGLVLSLD--IGAYTAAAFFG---LTAFCINGLEAYGNYRRSRQREVATQTI----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:.. * .** . * *:* :: :::.::** : * .* ::: .*: . **.** **: *.* * : : : .* .*. . :: :* ** :: :*: ** **.:** :*:.:. : * ::* * ::: :.: * ", "identical_positions": 38, "similar_positions": 57, "identity": "16.1%" }, { "cls_id": "homologset.agr.MGI:2142908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UIJ9-1", "uniprot_id": "MYZAP_MOUSE", "id": "Q3UIJ9-1", "name": "Myocardial zonula adherens protein", "aln": "MLRSTSTVTLFSGGGAKSPGTPSRRANVCRLRLTVPPENPVPQQTEKKIERKD--------------------------QPPE---LSNGESTKRLPQG--VVYGVVRRSDPNQQKEMVVYGWSTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQDLSVSHAQQDYLDSHIQAQASALDSFNAMNAALASDSVGLQKTLVDVTLENSHIKDQIRHLQQTYEASMDKLREKQRQLEAAQMENQLLKMRVESSQEANAEVMREMTRKLYSQYEEKLQEAQRKHSAEKEVLLEETNSFLKAIEEANKKMEAAELSLEEKDQKIGELDRLIERMEKERHQLQLQLLEHETEMSG--EMADSDK---NRYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPKTEVET--REIGVGCDLLP------------------------------------------------------------------------------------SPTGRTREITMPSRSYTPYTRVLELSSKKTLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXR5-1", "uniprot_id": "A0ABK0LXR5_RAT", "id": "A0ABK0LXR5-1", "name": "", "aln": "MLRSTSTVTLLSGGSAKSPGTPSRRANVCRLRLTVPPENPVPQQKEKKIERKDQHLEECFRRLGGQARPETPGSGIQVAQPPE---LSNGESTKKLPQG--VVYGVVRRSDPNQQKEMVVYGWSTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQDLSVSHAQQDYLDSHIQAQASALDSFNAMNSALALDSVGLQKTLVDVTLENSNIKDQIRHLQQTYEASMDKLREKQRQLEAAQMENQLLKMRVESSQEANAEVMREMTRKLYSQYEEKLQEAQRKHSAEKEVLLEETNSFLKAIEEANKKMEAAELSLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSG--EMADFDK---NRYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPKTEVET--REIGVGCDLLP------------------------------------------------------------------------------------STTGRTREIAVPSRSYTPYTRVLELTSKKTLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CAP1-1", "uniprot_id": "MYZAP_HUMAN", "id": "P0CAP1-1", "name": "Myocardial zonula adherens protein", "aln": "MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKE--------------------------QLLD---LSNGEPTRKLPQG--VVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSG--ELTDSDK---ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVET--REIGVGCDLLP------------------------------------------------------------------------------------SQTGRTREIVMPSRNYTPYTRVLELTMKKTLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TAE9-1", "uniprot_id": "A0A8N7TAE9_DANRE", "id": "A0A8N7TAE9-1", "name": "", "aln": "MLQNGMVGANSTTATTEIQDLNERR--IRRLRLTLRPDD-SPKTPNESVNSGEKVVNGTWKKKNGLMQRERP-PGRESPQPEDKHLVTNGIGREQSAQNGPRVYGVVQSSGTNQQQEVMAREWSVNQLRDEMRYIREVRDSLEKVRERMYGQFGGMQQSMQKLTQDLKAANSHKRYLESEVKTRRAAMESFDQMNNSLISANIDLQKSLLESCNNRVGNRDEMKTLRSAMEKTEEKLKETERQLAAAQAENRTLKHQVETSQEANTQALKELSAKLQREYEEQLQEQQRKYREEIEALQAQLDDYMKRLEEAEKNAQIAEAKIAERDQRIAEVERLLNCMAQEKGDLIKKLCDCEQRLRGLDETDHADKAAAKQSEQLKGEAAELRERIKHLNDMVFSQQRKVKAMIEEVESLRAKVAQKDMFITELLDRIAIVECENNELEDKLKYFMSIQKASEIKVSTRDIGVGCDLPVRSEEPPYVAPFQPNHVSSAPRSSSRLSNSLLKYTPGQYSTMLRSTVVHTQETMTSTTQTAPPSSLHGQSRHEVSESESPAASEVSSSISPRARTSPSQVYTPFMRLMEMSAKMNIE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CAP2-1", "uniprot_id": "GRL1A_HUMAN", "id": "P0CAP2-1", "name": "DNA-directed RNA polymerase II subunit GRINL1A", "aln": "---------------------------MCSLPRGFEPQAPEDLAQRSLVELREMLK-----------------------------------RQERLLRN-----EKFICKLPDKGKKIFD---SFAKLKAAIAECEEVRRKSELFNP-VSLDCKLRQKAIAEVDVGTDKAQNSDPILDTSSLVPG--CSSVDNIKSSQTSQNQGLGRPTLEGDEETSEVEYTVNKGPASSNR--------DRVPPSSEASEHHPRHRVSSQAEDTSSSFDNLFIDRLQRITIADQGEQQ---SEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQND------------------SSSHCQK-----SGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQK--LAERLNIKMRSYNPEGESS----------------------------------------------------------------------------------------------------GRYREVRDEDDDWSSDEF-----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . *: .. :: : .: :. . . :: :::. * :*: : .:** . * .. : : :: : :: . :: . *:. . . .: :: : . .* :. :: : . :. : : :* :: .:: : :*.:. * .:. : :: . . * *: * :. : . . *: : : * : :: :.. : : :: . . :* . *. :**:*:. .: :: * :: *:. .: :. : : : : :: * .:*. . * . ::. ", "identical_positions": 27, "similar_positions": 133, "identity": "4.59%" }, { "cls_id": "homologset.agr.MGI:2142951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M7Z1-1", "uniprot_id": "F1M7Z1_RAT", "id": "F1M7Z1-1", "name": "Enhancer of mRNA-decapping protein 3", "aln": "---EAMDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQQFG---------------------DLHQTELGPSGVGYQMSINQ---------------------NGTGKVVKKPASSSSAP--------------------------------------------------------QSIPKRTDMKSQDVAISPQQQQCSKSYVDRHMESLSQSKS---------------------------FRRRHNSWSSSSRHPNQATPKKSGLKNG-QMKNKDDE-----------CFG-DDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERR-SGSRSRGVPNER--PARYRHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKG---AQGISCGRHLAN--HDVQVILFLPNFVKMLESITN-ELSLFSKTQGQQVSSLRDLP------TSPVDLVINCLDCPENAFLRDQ-------PWYKAAVAWANQNR--APVLSIDP----------PVHEVEQGIDAKWSLALGLPLPLG---------------EHAGRVYLCDIGIPQQVFQEVGIDYHSPFGCKFVIPLHSA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2D3-1", "uniprot_id": "EDC3_MOUSE", "id": "Q8K2D3-1", "name": "Enhancer of mRNA-decapping protein 3", "aln": "---MAMDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQQVG---------------------DLHQTELGPSGVGYQMSISQ---------------------NGTGKVVKKPASSSSAP--------------------------------------------------------QSIPKRTDVKSQDVAISPQQQQCSKSYVDRHMESLSQSKS---------------------------FRRRHNSWSSSSRHPNQATPKKSGLKNG-QMKNKDDE-----------CFG-DDIEELPDTDFDFEGNLALFDKAAVFEEIDTYERR-SGSRSRGVPNER--PARYRHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKG---AQGISCGRHLAN--HDVQVILFLPNFVKMLESITN-ELSLFSKTQGQQVSSLRDLP------ASPVDLVINCLDCPENAFLRDQ-------PWYKAAVAWANQNR--APVLSIDP----------PVHEVEQGIDAKWSLALGLPLPLG---------------EHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F86-1", "uniprot_id": "EDC3_HUMAN", "id": "Q96F86-1", "name": "Enhancer of mRNA-decapping protein 3", "aln": "---MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQHFG---------------------DLHQTELGPSGAGCQVGINQ---------------------NGTGKFVKKPASSSSAP--------------------------------------------------------QNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKS---------------------------FRRRHNSWSSSSRHPNQATPKKSGLKNG-QMKNKDDE-----------CFG-DDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERR-SGTRSRGIPNER--PTRYRHDENILESEPIVYRRIIVPHNVSKEFCTDSGLVVPSISYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKG---AQGISCGRHLAN--HDVQVILFLPNFVKMLESITN-ELSLFSKTQGQQVSSLKDLP------TSPVDLVINCLDCPENVFLRDQ-------PWYKAAVAWANQNR--APVLSIDP----------PVHEVEQGIDAKWSLALGLPLPLG---------------EHAGRIYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502M5-1", "uniprot_id": "EDC3_DANRE", "id": "Q502M5-1", "name": "Enhancer of mRNA-decapping protein 3", "aln": "---MALDWVGNLVSIHCGPTLGVYQGEISSVDQTSQTISLRNPFHNGVKCTVPEVTFSAMDIKDLKILEISK--NSIEVS---------------------KQNGPESSSTTLMPHVGRKD---------------------KGGGGGGGG-APANSAP--------------------------------------------------------VMVPNKAEPRLQEGGVSPVP-HYSKSYGERHIDMAVQGKG---------------------------FRRRHNSWSSSCRGPNQATPKKNGLKNGGHMKNKDDE-----------CFG-DGMDDVLDEDFDFEGNLALFDKAAVLSQIESSERRGNGARSRGTPGEQT-PSRYRHDENILEAKPVVYRQITVPQNGSKEYSTDSGLVVPSISFELHKRLLAAAESHGLSLERRLEMTGVCASQMALTLLGGPNRLTPKNVHQRPTVALLCGPHVQG---AQGISCGRHLAN--HEVEVVLFLPNFVKMLEAITS-ELALFGKTGGRLVSNVKDLP------ETPVDLVINCLDSHENGFLRDQ-------PWYKAAADWANQNR--APVLSIDP----------PVSGQAHAVEAKWSLSLGLPLPLS---------------EGAGRVYPCDIGIPRQVFQEVGIKYHSPFGCKFVIPLHSE----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVI2-1", "uniprot_id": "EDC3_DROME", "id": "Q9VVI2-1", "name": "Enhancer of mRNA-decapping protein 3", "aln": "MGPTDQDWIGCAVSIACDEVLGVFQGLIKQISAEEITIVRAFRNGVPLRKQNAEVVLKCTDIRSIDLIEPAKQDLDGHTAPPPVVNKPTPVKLPHFSNILGKQQQLQLQQQQQQLQLQQQQKQQFQEQEREQDLPSTPRSRANDNGRVAAGGASSSSGPRGNFNSALSDKMHQLKLIETNGSNGTLRTPQTSRASSAQQQPQISTTPNSVAAFFGNMIPPKVEVKLGSYVSNTRESYCSSSGDSGEATGLSLGSSKPIDIVSNGDGFYKQTAASSYGNTNGNVRRNGNANNNGNGTGNGSYTNGNGNGNGKNKRNRVRRESSMRQQQVQLTFGSEADDPLIHEDFDFEGNLALFDKQAIWDDIESTTQKPDVVRHIVNNHHHKPEQKYRHDENILASKPLQLRQIESMFGGSQDFVTDDGLIIPTIPAYVRNKIEISADKAGLSLQRQIDILARGASDLAITLLGGARRLTPANNHQWPKIAIICDGGKNMRTINIGAATGRQLAS--HGLTVLLYVEQAKLLEQNSSSPEISLFKATDNVIVHSVDALP------TPDLVILSTNTANLSDAIRKWL-------SVNRASVLAIDPPP--CGINEVAIKYSILP--ILPLNGISTATTSSSSSAAATPTPIASTSAAASATKSAASTNNCGKLYLCNLGIPDKFYRDCGIKYKSPYGHKYVIPIHSKD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39998-1", "uniprot_id": "EDC3_YEAST", "id": "P39998-1", "name": "Enhancer of mRNA-decapping protein 3", "aln": "----MSQFVGFGVQVELKDGK-LIQGKIAKATSKGLTLN-DVQFGDGGKSQ--AFKVRASRLKDLKVLTVASQSGKRKQQR--------------------QQQQQNDYNQNRGEHIDWQD---------------------DDVSKIKQQEDFDFQRN--------------------------------------------------------LGMFNKKDVFAQLKQNDDILPENRLQGHNRKQTQLQQNNYQ--------------------NDELVIPDAKKDSWNKISSRNEQSTHQSQPQQDAQDDLVLEDDE---------HEYDVDDIDDPKYLPITQSLNITHLIHSATNSPSINDKTKGTVINDKDQVLAKLGQMIISQSRSNSTSLPAANKQTTIRSKNTKQN------IPMATPVQLLEMESITSEFFSINSAGLLENFAVNASFFLKQKLGGRARLRLQNSNPEPLVVILASDSNRSG--AKALALGRHLCQTGHIRVITLFTCSQNELQDSMVKKQTDIYKKCGGKIVNSVSSLESAMETLNSPVEIVIDAMQGYDCTLSDLAGTSEVIESRIKSMISWCNKQRGSTKVWSLDIPNGFDAGSGMPDIFFSDRIEATGIICSGWPLIAIN--------NLIANLPSLEDAVLIDIGIPQGAYSQR-TSLRKFQNCDLFVTDGSLLLDL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* *.: : ** : *: : . . . : .:.:: . . . . : : :: .: .. . . : : : . . . . .. . :: .. : : : . :. . :. : : : . *:: : : * . . : . : :... : * :: ::: : : . : : :: .:. :: . ** : *** ** * : * :.::.. . . : **:*.. * : *: . : : . : :: . * .: * . : :: . : . :: : : .: * :. . . * ::*** : : . :. . . .:. * ", "identical_positions": 30, "similar_positions": 146, "identity": "4.27%" }, { "cls_id": "homologset.agr.MGI:2142973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZU78-1", "uniprot_id": "A0A8I5ZU78_RAT", "id": "A0A8I5ZU78-1", "name": "leucine--tRNA ligase", "aln": "MASACQRLSFCVSPLKRQLVSGLPVILWER-IIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKVQASKISEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALAD--LPEWYG-IKEMQAHWIGDCVGCHLDFTLKVDGQDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSLKTALQKALVPGR---------DCLTPVMAVNMLTLQEVPVVIMAKPDLEG--SLDSKIGIPSTSSEDTRLAQA--LGLPYSEVIETSPDGTERLS----------------------GSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLVSRQRYWGTPIPIVHCPACGPVPVPLQDLPVTLPSITSLTGRGGSPLASALEWVNCSCPRCKG-SAKRETDTMDTFVDSAWYYFRYTDPHNTHSPFSSALADFWMPVDLYIGGKEHAVMHLFYARFFSHFCHRQKMVKHR----EPFHKLLAQGLIKGQTFHLL-SGQCLKREDIDFTGP-----TPVCAKTKERLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTAPQPQLLNNKEKAKARSLWEYKNAVITQVTTHFTEDFALNSVVSQLMGLSGALSQASQRLVLHSPEFEDALCALLVMAAPLAPHITSELWAGLALVPSKL---CDRYAWDAGVMLQAWPTVDSQF-----LQKPDMVQMAVLINNKACGKIPVP--QHVAQDQDKVHEFVLQSEL---------GIKLLQGRSIRKAFLSPRTALINFLVKE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDC0-1", "uniprot_id": "SYLM_MOUSE", "id": "Q8VDC0-1", "name": "Probable leucine--tRNA ligase, mitochondrial", "aln": "MASTCQRLSFYVSPLKRQLVSRPPVILWER-LIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKEQASRVSEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALAD--LPEWYG-IKGMQAHWIGDCVGCHLDFTLKVDGEDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSVKKALQKALVPGR---------DCLTPVMAVSMLTLQEVPIVIMANPDLEG--SLDSKIGIPSTSSEDTRLAQA--LGLPYSEVIEASPDGTERLS----------------------GSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLISRQRYWGTPIPIVHCPACGPVPVPLQDLPVILPSIASLTGRGGSPLATALEWVNCSCPRCKG-SAKRETDTMDTFVDSAWYYFRYTDPHNTQSPFGSALADFWMPVDLYIGGKEHAVMHLFYARFLSHFCHDQKMVKHR----EPFHKLLAQGLIKGQTFRLP-SGQCLKKEDIDFTGP-----APVCAKTKEKLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTVPQPQLLNSKEKTKAQNLWEYKNAVIAQVTTHFTEDFALNSVVSQLMGLSSALSQASQRVVLHSPEFEDALCALLVMAAPLAPHVTSELWAGLTLVPSKL---CDHYAWDSGVMLQAWPTVDSQF-----LQKPDMVQMAVLINNKACGKIPVP--QHVAQDQDKVHELVLQSEL---------GMKLLQGRSIKKAFLSPRTALINFLVQE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15031-1", "uniprot_id": "SYLM_HUMAN", "id": "Q15031-1", "name": "Leucine--tRNA ligase, mitochondrial", "aln": "MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPEWYG-IKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGK---------DCLTPVMAVNMLTQQEVPVVILAKADLEG--SLDSKIGIPSTSSEDTILAQT--LGLAYSEVIETLPDGTERLS----------------------SSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKG-AAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHR----EPFHKLLAQGLIKGQTFRLP-SGQYLQREEVDLTGS-----VPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKL---CAHYTWDASVLLQAWPAVDPEF-----LQQPEVVQMAVLINNKACGKIPVP--QQVARDQDKVHEFVLQSEL---------GVRLLQGRSIKKSFLSPRTALINFLVQD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZ82-1", "uniprot_id": "Q9VZ82_DROME", "id": "Q9VZ82-1", "name": "leucine--tRNA ligase", "aln": "MQALRRTRPWGAVYWN----------SWRRLLTQSCTR-------NDNPELTSDVKHRIEAHWREQLSGGQFNPKDS---QDKYYVLSMFPYPSGNLHMGHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAENAANQRGVEPASWTEQNIAQMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRD-IINLQRHWIGECDGYAFNLLTSASG-----LLRVWTTHPEHLKDP------------HAFLVLRSNHHLSKLKGA---------DSLS---AANPFAGTTMPVVFSDEVTFPP--KSDVYLAAPSFRGEDKDLWDS--YGLAFTS------NGKDEES----------------------LSPANWEMLRKEVLQAATR----LNVGGYRVSSKLKDWLISRQRYWGTPIPIVHCQKCGAVPVPEEQLPVSLP-----------PKDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTS----EPFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKK--NQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPTSHRNWSSAT--FPGILNWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLAEDAKLFDARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAYNLDLSIKVNGFENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVLYPGIEAILNIYVDKAKMKQKPPTTDDAEAQPQA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11325-1", "uniprot_id": "SYLM_YEAST", "id": "P11325-1", "name": "Leucine--tRNA ligase, mitochondrial", "aln": "MLSRPSSRFLST---------------------------------KRGPGPAVKKLIAIGEKWKQKTTRG--LPKQDTLNSGSKYILCQFPYPSGALHIGHLRVYVISDSLNRFYKQKGYNVIHPMGWDAFGLPAENAAIERSINPAIWTRDNIAKMKQQMQSMLANFDWDREITTCDPEYYKFTQWIFLKLFENGLAYRKEAEINWDPVDMTVLANEQVDAQGRSWRSGAIVEKKQLKQWFLGITKFAPKLKKHLNQ--LKDWPSNVKQMQKNWIGESVGAELVFKVADPKFEN---LIVFTTRPETLFAVQYVALALDHPIVQKYCEEMPDLKEFIQKSDQLPNDTKEGFQLPNIKAVNPLTKEEVPIFAAPYVVSSYGSAPSAVMGCPGHDNRDFEFWQTNCPGEHIKTCIAPFFDDASKVTEQERQRIIDTVPFTSTDGVLTKECGEHSGVLTVVARKSIMGMLNSEGLSKSVVRYKIRDWLISRQRYWGTPIPIIHCDNCGPVPVPESDLPVKLPELEGLDTKG-NPLSTIDEFVNVACPSCGS-PAKRETDTMDTFIDSSWYYFRFLDPKNTSKPFDREIASKNMPVDIYIGGVEHAILHLLYSRFIAKFLGSINAWSDPAGIFEPFKKLVTQGMVQGKTYVDPDSGKFLKPDELTFVNDSPDGNTVIIKSNGKVPVVSYEKMSKSKYNGADPNECILRHGPDATRAHILFQSPIADALNWDESK--IVGIERWLQKVLHLTKNILSLEKDLAISKDYKTPTDLNDAEVKFHNDFQRFLKSITESFEVNLSLNTVISDYMKLTNILESALKKGEVRNEMIVQNLQKLVTVIYPAVPSISEEAAEMINSQMEWN--------------QYRWPEVERTT-------ESKFKKFQIVVN-GRVKFMYTADKNFLKLGRDAVIETLMNLPE---------GRMYLMNKKIKKFVMKFN--VISFLFHK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : : . : *::: . .: . . *:*. ****** **:**:***.::*:: ** : * :*::*****:********* :*.:.* **..** :*::*:. : *.*::*::** *.***:** :*: *.. ****::** :****** ****:***: * ****** **:* *:***: : :* : . * : * :* . : :* :***:. * : : * .:*: ** : : : . *. *.. :: :*:. . :. *. ..* : :: * . :. .. : . : . : :. . *::***:************:** **..*** .:*** ** * * . ** * *:*********:**:***:*: *.:*. *. ::. ****:**** ***::** *:**: :* *** :*:.**:: *::: **: : :: :.. : .. : :::******* **.:*.: . .:* *: * ** . . *. . : *: .* ::: : . . . .. . .: : : : * : *. .:*. *:. * : : :. : * : : * .* .:.* : ** :: . : : :: : . : . : * . ::: * : . : * :. . . . ", "identical_positions": 219, "similar_positions": 232, "identity": "22.48%" }, { "cls_id": "homologset.agr.MGI:2142979", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A518-1", "uniprot_id": "D4A518_RAT", "id": "D4A518-1", "name": "", "aln": "MIEDKGPRVADYFVVAGLTDISKPLEEEIHFNDACHK-VARPKEPITDVSVIIKSLGEEVPQDYVCIDVTPTGLSADLNNGSLVGPQIYLCYKRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENTTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPQEDYESFSLPES--VPLFCLPMGATIECWPPDS-----KYPLPVFSTFVLTGAS-AEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSLVDGKSDGSRTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGP-HALPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKNVAWKILPKKPCKNLMNTLHNLHQQLAKLQQRPRDDGLMDLAMNDYDFNSG-KRLHMIDLEIQEAFLFFMASILKGYRSYLRPITEAPSETATDATSLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVD---------KVDTDKSGEVRLIELDASFKSEHTVFVTPPE----IPQLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQARKNKLPSKPSSPGSPSPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVR---ALKTAYDVLKKMQLKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWP-SRSRSGYFLWTKIRNVVLGVAQFKRALKKHPHLPQTALSGGRSDLGYSSLCKDDVRREATSTEDIQGEKDKKGSDSSSLSENESAKG-SADCLPSLSYQSSSTIVRLSGTNQDGADKMSGECEESTPELLLVPSCNDTNEAQTMPSRCFRKRHKSDDESHLQQQMPWGNRNRNLSGGVLMRFMLNRINQETNPGDMVEKLGADAKILSNVISKSTRPNSLDIG-KPPVRSKRDSLEKESSDDDTPFDASN--CLDKVESPVIFDLEDLDTETDGSKVGCVAAQNPKRLQRMNSSFSVKP--SEKTDVVTGFDPLSLLVAETEQQQKVEEEDDEDDNKSISTPSARRNLAEEIEMYMNNMSSPLTSRTPSIDLQRASDEKLTNKKSPTLVKACRRSSLPPNSPRPVRLTKSKSYTKSEERPRDRLWSSPAFSPTCPFREGSQETLAHSSPSFNLDTLLVPKLDVLRHSVFTAGKGVAEKASKWYSRFAMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGATSSQESSAASGT---KGIDASRASLGSSASLEGSLSKFALPGKTETAS--------SLNTSNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLNVEIRDLRRPGRYFLKSSSSTETMHFASSFSSRTRQSCISASASGLDTSSLSVQGNLDLNNKSKLQENPCARSIQIPAHRSKTVVSKCPLFPMARSISTCGPLDKDEPGGQKLIPTGSLPATLQGPTDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSS-EHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDP-GQPLYILWNAHSQNRTLLFETQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLS--KCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHN-CDRPPSTGVMECRKTFGEPYL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8V6-1", "uniprot_id": "E9Q8V6_MOUSE", "id": "E9Q8V6-1", "name": "", "aln": "MIEDKGPRVADYFVVAGLTDISKPLEEEIHFNDACHK-VAKPKEPITDVSVIIKSLGEEVPRDYVCIDVTPTGLSADLNNGSLVGPQIYLCYKRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENTTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLSNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPQEDYESFSLPES--VPLFCLPMGATIECWPPDS-----KYPLPVFSTFVLTGAS-AEKVYGAAIQFYEPYPEENLTEKQRLLLGLTSLVDGKSDSTRTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGP-HALPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAMNDYDFNSG-KRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDATSLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVD---------KVDTDKSGEVRLIELDASFKSEHTVFVTPPE----IPHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQARKNKLPSKPSSPGSPSPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVR---ALKTAYDVLKKMQLKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWP-SRSRSGYFLWTKVRNVVLGVAQFKRALKKHPHLPQTALSGGRSDLGYNSLSKDNVRREGPSTEDIQGEKEKRGSDSSSLSENESTKG-SAECLPTLSYQRASTIVRLNGAHNDSAGKTSGECEESTPELLLMPSLEDTNEAQTTPSRCFRKRHKSDDGSHLQQQMPWGSRNRNLSGGVLMGFMLNRTNQETSPGEMVEKLGADAKILSNVISKSTRPNSLDIG-KPPARSKRDSLEKESSDDDTPFHGSN--CLDKVESPVIFDLEDLDTETDGSKVGGVAAQNPKRLQRRNSSFSVKP--SEKTDVVTGFDPLSLLVAETEQQQKVEEEEDEDDNKSVSTPSARRNLAEEIEMYMNNMSSPLTSRTPSIDLQRACDDKLTNKKSPTLVKACRRSSLPPNSPRPVRLTKSKSYTKSEERPRDRLWSSPAFSPTCPFREGSQETLAHSSPSFNLDTLLVPKLDVLRHSVFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGATSSQESSAASGT---KGIDVSRASLGSSASLEGSLSKFALPGKSETAS--------SLNTSNANIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLNVEIRDLRRPGRYFLKSSSSTETMHFAS----RTRQSCISASASGLDTSSLSVQGNFDLNNKSKLQENPCARSIQIPAHRSKTVVSKCPLFPMARSISTCGPLDKDDPGGQKLIPTGSLPATLQGHTDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSS-EHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDP-GQPLYILWNAHSQNRTLLFETQKYPMVHLLQKGDDSFNQELLKSMVKSIKMNDVYGPMSQILETLN--KCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHN-CDRPPSTGVMECRKTFGEPYL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z401-1", "uniprot_id": "MYCPP_HUMAN", "id": "Q7Z401-1", "name": "C-myc promoter-binding protein", "aln": "MIEDKGPRVADYFVVAGLTDVSKPLEEEIHFNDACHK-VAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPES--VPLFCLPMGATIECWPSNS-----KYPLPVFSTFVLTGAS-AEKVYGAAIQFYEPYSEENLTEKQRLLLGLTS-ADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGP-HVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSG-KRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVD---------KVDMDKSGEVRLIELDESFKSEHTVFVTPPE----IPHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVR---ALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWP-SRSRSGYFLWTKVRNVVLGVTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKG-SADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIG-KPPLRSKRDSLEKESSDDDTPFDGSNY-LADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKP--FEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLN-KKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGT---KRIDLSRISLESSASLEGSLSKFALPGKSEVTS--------SFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSS-EHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDP-GQPLYILWNAH---------TQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLN--KCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHN-CDRPPSTGVMECRKTFGEPYL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286Y972-1", "uniprot_id": "A0A286Y972_DANRE", "id": "A0A286Y972-1", "name": "", "aln": "-MEEKSLRVADYFVVAGLTVSSKPLEEDVHPEDGAHRSSAQLKAPITDVAVVIRSLGEEVPRGYTCVECTPSGLPAELNGGSLMGPQIFLCYRRGRDKPPLTDLGILYEWKEKLKPDCQIIQTTPSGRPANISGS-SSQRIYITYRRAAENHSHATLAVTDICVIIPGKGETPPHAFCKVDKNLNSSMWGSSVYLCYKKSLAKTNTLAFKAGLLSRYPEEDYDSFPLPES--VPLFCLPMGASIECWSSHT-----KYSLPVFSTFVLTGAS-GEKVYGAAIQFYEPYPEEHLTEKQRSQLGLQA-NGIRPDGSMTVHTNKSICLLSHWPFFDAFRNFLTFLYRYSISGP-HTLPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPVSSPLPLSGGRLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYEPPTDISCVDLDTNTITHKEERRSLTWKILPRKACKHLINTLSNLHQQLDEGYQMSREEGQMEAFMSEREPGSGGKSLETLELEIQEAFLRFMAAILKGYRSYLLPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKLFGTEKGGKVDSDKPEDTRLIELDKSHRSEHTVFISPPE----LPALPEGEEPPMVYSYSGFPALNAQLCEHQDG-LRVPKATSALRHISPISPAAIFRRSQQEIKSAQRMAKTYSSIPQMWSKCLLRHCHGLWFICLPAYVSACHSKVR---ALHTAYDVLRNMQDKKLQPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMKKAGVQPNAITYGYYNRAVLESTWP-SSTRGGYFLWGKLRNVVRGVVLFKQVWRRQTTHPKDTHLSDASDL--DSVSHGSLDSSNDSAERVSIDTDFTKMDSS--DDRSSTGGQSDQGYDSLSKEE----VRFGG----------GEEQNSSPDIKEK---KDRDSCPSSQSELSKKEDSS------------------LAAGIHP----PEINKESS------------QAFSNTIPKTKRPNSLDIFGEKPVRPNTLDLTPDKPVDSVPVAQTQTEALEGVVSPPKVSVERKASCTVTMEKTVAMESGHTGVERSMSCNSALSRVVKRTGIEAGFDPLSLMAAETHG------HEDEDN---AGTPSARRDLAEEIHHYMNNLSSPLSQRSLSVDLK--GHQTPSPHSSPCMSKIALGS---PSASQLQPQPRTRLFS-SPSLPQGRVRRVREQRPTS---LASPSSPTPSSSSFSMDSLLTPTLDVFKSSFLSAGKGVAEKASRLYSRLSSQTSIAQDLNSDRVSVSSLGSGDPDCSSLIESDLCVDPEGLSSPQRDAAQPVIRPRKSPHRSNNCLESPSAAPRLFRQASLTGPSLTVMKALQTPDTCSDSSFSQFTQSYAVEVRMSSCSRCNTCESLVYDEEIMAGWTADDSNLNSTCPFCGSPFLPLLNVDITNMGE-----------------------QERSPCQDTSSGQTEREDEPPK-----------------------------------VYDASSTLSNK---DKKD-------------------------------PETVTVPYLSPLVLWKELESLLENEGDQAISSAAIVDHHPIVFWNLVWFFRRLDLPSSLPGLYLTSKNYCRDTPQSQQSCASEDSKNVLVQILWDNCRLHQDH-IQPCYLLWKSY---------CLSTAVSSSLNEDEQAVSLELLQTLVKNIQKNDVYQPMSLILQLLG--SRLGFSRQRSLYRDILFLSLVALGKSSINIDAFDREYKTAYDRLTPSQVKMTHN-CDRPPSAGVMECRRTFGLPSL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3D3-1", "uniprot_id": "CRAG_DROME", "id": "Q9W3D3-1", "name": "DENN domain-containing protein Crag", "aln": "-MEEK--RIADYFVVAGMPENPQLLQENSFNDSGRLR-AATTIEPITDIGVYFPLLGEEVPEGYEILSHTPTGLQANLNHGSVRTTDCYIYFRRGKDRPPLVDIGVLYDGHERIMSDAEIVAETPGGRVANVNNS--SAKTFLTYRRARADMPCNELVVTELCVIVQSKGERAPHAFCLIYKTLNKGYVGSDVYLCYKKSMYRPKHISYKPEILLRYPTFDHTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPVFSTFVLTVSDGTYKVYGSALTFYEDYDESKLSAEQKELLGWDEEFGAQHS----LHMIKAICLLSHHPFGDTFDKWLKYLHRMVLYDVNIPIPVERYITQLLDEVPFPAPS-IHLQLSSESNDRILLTQPEDSPLPRSGAGFHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTDVTCIDLDTNNISLCESQRHLSPKLLPKRAARLLRQTLTELENAKPISYDSTN--------SLDRDIRKR-KRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLKAFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLSFFDECAEKVG-------NYDETPAQLHLVDWDTGQNSERTKYIFPPDSVTPAGSQPGGGGGGLAYNYENFTLQPELLQSTKKTALSKFLQLQLNASLSPGSP--IARRTKHEIKLSQKMASRCQQHPEAWSKYLLATCYSLYFLILPSMVLDPRHAGKEPEILRAAYDVLVRASRLKIT-CDEFCYRIMMQLCGIHNLPVLAVRLHYLMKRSGVQANALTYGFYNRCVLESQWPQDSTTISQIRWNRIKNVVLGAAQFRKAGKQRAASKVNKSLSASQDQNLSTLETVDGQSRTSLASSSGDGGGHGLLDFAAFDRLRNKLG----------------------------------------SIVRQTVTGGNNETMGDAVNN---------------------------TGLLIPGELSAPNTPTYGG--------DTEILAKALQQQQPRKQIMSIGGGDDDDEDEDEDEYTAGSPSTPQKQLEAGADDLEYAGGGDYEADEEDEDEVDEHVAAQRARQRVQSPTKISPRTP--------VTQNDPLGALNEEESAASATPTQETQQEQQHSQSQIDSSIYSDKPILFRGQRSATFDESTQIGKSMHRSETMPVASSGVTNSLANIGSSLKFTFGRYSPARLS--LKKDLKLPANIIENISSISPSLTGKKSNELIQGSLSSIKSAANSLTKKFDEIKGVISANSTPTKTNNGHHPHGLHHGHHHPHHHHHHHSQHGNAEQEEHDAAVHEEGKLRRVSSDLDPWGRLSESRKS------SYNNLVPLGENSSTGALHMHAFPAVPDNLY---------SLTSENAADRDCDVLIQLTTCSQCHNCSVLVYDEEIMSGWTAEDSNLNTTCHACNKLTVPFLSVQIERQVEE----------------------SEQSDPLQDGKEQIANGN--------------------------------------------------------------------------------------SHKTSLTVPYLNPLVLRKELENILTQEGDIALIKPEFVDEHPIIYWNLLWLMERIESKTHLPELCLPVPSDKEHIDPLS------KVKTVHIQCLWDNLSLHTEASGPPMYLLYRET---------QPTSPLIKALLTDQAQLNKNVIQQIISAIRCNDFATPLKRLANERHKLKSNGVERSHSFYRDILFLALTAIGRSNVDLATFHREYAAVFDKLTERECNMYYRNQDLPPSASTIFCRAYFRPLLLP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* *:********:. .: *:*: . :.. : * ****:.* : ******..* :. **:** *:** **: .: :: ::**:*:***.*:*:**: :*:: ..:*: ** ** **:..* * : ::***** : . *.**::*:*: .*** .**:** : *.*... ** ********: :.: :::*. :: *** *: .*.* . **********::*.*. . * ********* :. ****:*: *** * *.:*: :*: ** . : . :* *.****** ** *:* ::*.:*:* : . :*:*::*::::.:****:.. :: :. ..:* ::*:** .**** **. : ** ***..*. :*::*:**:***:*****:.**:*:**:**::***:* ***:*****.**:** ** *:::*:***:****:**.*::*:*:***.*: .:: :: *:**::..: * :** :*.: : .. : : . * :: .****** ***:**:***.:* **::*** ***.::** *:.**:***:*****:.:* *********** ***** * .*:***:*.: :.. : :*:: * . .**:* :: **: * * : *.*..*. * . . * ** ** : **:::*** ::::*. .. *: **: ** *:.*:*: **: * : : *::***** . . *: **.***::***** :. ******: : *:::*::.**:***:**:.**** ** . : . : * :::*** *.. *::. :::. . .* .:: . :. * : . . * .: . :. . *: * : : :::.: : : : : . .. . . : : . . * . . :: . . . : ***. : * .: ::: : ::: : .: *:.: . : . . .. * . : : . . . * . : *: . *. . . *. .:* :: . : .. . : .: : .:. .: . .. : :.: : .: .. . . : .. . : : ::.. . :* :. : : :::**:*..*. **:*****:****:*****:** *.. :*:*.::* . :. . . .:*****.***: ****.:* :*** *: . :**.***::***:* :.*:: : ** * *. . .. . * * :* **** ** : * *:*:. . .: * .: .. :::: ::. *: **. *:. : : . ..*.:*:**:****:*.*:*:..::: :*.:** .:*:** : : :. * ***:..: ** * * ", "identical_positions": 483, "similar_positions": 520, "identity": "25.1%" }, { "cls_id": "homologset.agr.MGI:2142980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYW8-1", "uniprot_id": "D3ZYW8_RAT", "id": "D3ZYW8-1", "name": "Transmembrane protein 266", "aln": "--------MASPQPAIEGGISEVEIISQQVDEETKNIAPVQLVNFAYRDLPLAAVDLSTGGSQLLSNLDEEYQREGSNWLKPCCGKRAAVWQVLLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAAVIHWISLVILSVFFSETILRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMFRIWRVKRVIDAYVLPVKLEMEMVTQQYEKAKAIQDEHLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRYKVVEAGTWAEETAAESIMEELRPSQEAMVKDDMNSYISQYYNGPSSDSGAPEPAVCVVTTAAIDIHQPN----ITSDLFSVDLP-LKLSGNSTCASATSETTSHPTCGSVTRAQSASSQTLGSSTDCSTPREELS----------SKPISSPLPLLLPPQQLVAEATVQDLMSSLSKDPCPSHK-ALDPAPLAQPTPVGSVQTSPELEHRVSLFNQKNQEALPVLQIKPVIHLQPTAG-LEEKFRSLESKEPKLHTVPET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZB3-1", "uniprot_id": "TM266_MOUSE", "id": "Q8BZB3-1", "name": "Transmembrane protein 266", "aln": "MALVTSFNMANPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTGGSQLLSNLDEEYQREGSDWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDTKLLQFSNAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMFRIWRVKRVIDAYVLPVKLEMEMVTQQYEKAKAIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRYKVVEAGTWAEETAAESIVEELRPSQEATVKDDMNSYISQYYNGPSSDSGAPEPAVCVVTTAAIDIHQPN----VPSDLFSVDLP-LKLSGNSTCASATSETTSHSTCGSVTRAQSASSQTLGSSTDCSTPREELLP---------SKPRSSPLPLLLPPQQLVAEATVQDLMSSLSKDPCPSHK-ALDPAPLAQPTPLGSVQTSPELEHRVSLFNQKNQEALPVLQINPVIHLQPTAG-LEEKFRSLESKEPKLHTVPEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M3C6-1", "uniprot_id": "TM266_HUMAN", "id": "Q2M3C6-1", "name": "Transmembrane protein 266", "aln": "--------MTNPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVIQQYEKAKVIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVLEAGTWDEETAAESVVEELQPSQEATMKDDMNSYISQYYNGPSSDSGVPEPAVCMVTTAAIDIHQPN----ISSDLFSLDMP-LKLGGNGT--SATSESASRS---SVTRAQSDSSQTLGSSMDCSTAREEPS----------SEPGPSPPP--LPSQQQVEEATVQDLLSSLSEDPCPSQK-ALDPAPLARPSPAGSAQTSPELEHRVSLFNQKNQEGFTVFQIRPVIHFQPTVPMLEDKFRSLESKEQKLHRVPEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PGX9-1", "uniprot_id": "A0A8M9PGX9_DANRE", "id": "A0A8M9PGX9-1", "name": "", "aln": "-----MSQQTQAPQQTPAAAPDLEVISQQVEDEGQCMAPVQLVSFAYRDLPLAALDLSLAGSQLLSNLDEEDNQEGSNWLKPCCGRRAALWQVCLLSAGFNCFLVACVILVVLLLTLELLIDTKLLQFNNAFQFACIIHWISLVILSVFFTETVFRIVVLGIWDYIENKVEVFDGAVIVLSLAPMVASTVANGPSSPWDAISLIITLRIWRVKRIIDAYVLQVKVEMELEIQQYEKSKAVREEQLERLTQICQEQAFEIRQLRAHLAQQDLDLAAEREAAMQIHHVWGKQSSSFQEIDG----LRPAGAENSREPRAPAESVVQDDMNNYISQYYSEPSSDIGVPDPGARVITTAAIDVHLPTNPNQLPPSLVSADGPGSGQRTGSSVSEASSTTMSRSSCSFTARQHSVSSHTLGSTTDCSSTVREASTSDYSGQRCCPPPYCSPLTLGTQPGIHDPSAVVKELLSSLSEDSCLAQKGRVDPVNLKLPSPAGSVKASPELEHRVNIYNKRNQESLGVFQTKPLIHLQGTEPSLDEKYRLMEPADTPLSHIPDT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. .. .::*:*****::* : :******.**********:*** .**********: ::***:*******:***:*** ****.:*.**********:********* *****..***** :*************:**::**************:********:*************** ********** :*******:****** **:***: *****:*.:::*:***********.************************:* ** .: * :: ::. ..*. . .* :.. *: ::****.******. **** *.*:*.. ::******:* *. :...*.* * * ..: .*:* : *:. .:* :* **:****: ***:. .* . * ** . . .*.*::*:****:*.* ::* :**. * *:* **.::********.::*::***.: *:* .*:**:* * *::*:* :*. : * :*::", "identical_positions": 304, "similar_positions": 133, "identity": "54.87%" }, { "cls_id": "homologset.agr.MGI:2142985", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TNA1-1", "uniprot_id": "XYLB_MOUSE", "id": "Q3TNA1-1", "name": "Xylulose kinase", "aln": "MDARTHRRAAGTPRALAERAGRRCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILGKMKSSGFDFSQVLALSGAGQQHGSVYWKTGASLALSSLS--PALPLHQQLQS-CFSISDCPIWMDSSTTAQCHQLEAAVGGAQALSCLTGSRAYERFTGNQIAKLFQKNPEAYSHSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLDVCAP-----HLEEKLGSPVPSCSVVGTISSYYVQRYGFPPGCKVVAFSGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQKPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDES---------ASCSWNKFSKALKSTAMGNNGNLGFYFDVMEITPEIIGRHRFNAENMEVSA--------FPG-DVEIRALIEGQFMAKRIHAEGLG----------------------------YRVMPKTKILATGGASHNKDILQVLADVFGAP-VYVIDTTSS-ACVGSAYRAFHGLAGG-----------------TGVAFSEVVKS-APQP--SLAATPNPGASQVYAALLPRYSALEQRILSTAQ----RPLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3MIF4-1", "uniprot_id": "XYLB_RAT", "id": "Q3MIF4-1", "name": "Xylulose kinase", "aln": "---------------MAERAGRRCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILEKMKASGFDFSQVLALSGAGQQHGSVYWKTGASLALSSLS--PALLLHQQLQA-CFSVSDCPIWMDSSTTAQCHQLEAAVGGAQALSCLTGSRAYERFTGNQISKIFQKNPEAYSNSERISLVSSFAASLFLGRYSPIDYSDGSGMNLLQIQEKVWSQACLDACAP-----HLKEKLGSPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDVAVSLGTSDTLFLWLQKPMPALEGHIFCNPVDARQYMALLCFKNGSLMREKIRDES---------ASCSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGCHRFNADNMEVSA--------FPG-DVEIRALVEGQFMAKRIHAEGLG----------------------------YRIMPKTKILATGGASHNKDILQVLADVFGAP-VYVIDTTSS-ACVGSAYRAFHGLAGG-----------------TGVAFSEVVKS-APQP--SLAATPNPGASQVYAALLPRYAELEQRILSKAR----GPLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75191-1", "uniprot_id": "XYLB_HUMAN", "id": "O75191-1", "name": "Xylulose kinase", "aln": "---------------MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLS--PDLRLHQQLQD-CFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIYQQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAP-----HLEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNES---------VSRSWSDFSKALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAA--------FPG-DVEVRALIEGQFMAKRIHAEGLG----------------------------YRVMSKTKILATGGASHNREILQVLADVFDAP-VYVIDTANS-ACVGSAYRAFHGLAGG-----------------TDVPFSEVVKL-APNP--RLAATPSPGASQVYEALLPQYAKLEQRILSQTR----GPPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPT2-1", "uniprot_id": "Q9VPT2_DROME", "id": "Q9VPT2-1", "name": "Xylulose kinase", "aln": "-----------MCHRIKQDYSGNSYLGLHLGTQLFRALILDSKLNVTYVAQIRYDVDLPEFKTTNGILSDGGPGEFLANPVMWVKALDMLMDCLVKQGADMHTVVSIAGAAQQHGCVFWSELGLRRLCNLN--VNLRLHEQITESAFELTRTPTWRDSSTDVQVREMEHTVGGPAELSKITGSRAYTRFTGPQIRKVYTQCPEQYERTSRISLISSFLASLLIGGIASIDYSDGSGMNLLDIRKKKWSAACLDACAP-----DLARRLMKPIPSSRLQGRIGDYYVKRWNFRPDCMVVASTGSKASELAGLLVENDFLMLSLDTSDVVVMPLKKAPRLEDGHVMCHPTRRDEYMGLLCFQNGGLTRKAICEDV---------AGGSWRHFYEMLDATPSGNNGNVAVHFRDREIIPTAKGTLRWDAHISPMSAECIRGLHRFSTPEIEVRALIEGQIMHHWSIAHEMG----------------------------FHHTPNTKIIVVGEDSRCQSVLQIVADIFNAP-VYQR-TGVEVSLLGCAFRARYAFYEHRESACNCHSCMMPTGRRTRLSFDEFFRD-VPSG-LKLAAEPTPGCDKIYKPLIERCSQICQLLASKSSVYFFHPNV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VEQ0-1", "uniprot_id": "Q9VEQ0_DROME", "id": "Q9VEQ0-1", "name": "Xylulose kinase", "aln": "-----------MGPPKQLKR---TFLGFDLSTQKLKAVLLGSSLEVVAAAEVKFDTDLPEFRTTGGANAGSIKNEYFVQPVMWVKAMDIVLDRLVMQQADLSTVAAISGSGQQHGSLYWSKHGINTLQNLD--SEKFLHAQIDDSAFVVNRTPIWMDATTTKQCLEMEMAVGGKLNMVELTGSKCYERFTGPQIRKIYQQRCHAYEEANRISLVSSFISSLFLGSVAPIDFSDGSGMNLLDIRKKNWSKECLNVCAP-----DLDKRLDIPVSPNSILGNVSPYFVERFSFSPDCKVAASTGDNPSALSGMLVGSSWLTISMGTSDTLMMSLKEPLNWEEGHILCHPTETEEFMGLLCFRNASLVREEMNKKT---------TGGDWDKFNEYLDSTPRGNFGNMAVHFNDMEIIPKAQGILRWNREMDPSSPDAARGVIKFSSPQIEIRALVEGQMLHHRAVAEDLG----------------------------YKFGPETQILVTGGASVNKSILQTIADVFNAP-VHIQDEGFEAALLGAAYRSAYALYLQEAGDG-----------VTPLCYRDYILS-LTSNKLSLVCEPHKDSEEIYAPMLQRYREMARVLS--------NPNT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42826-1", "uniprot_id": "XKS1_YEAST", "id": "P42826-1", "name": "Xylulose kinase", "aln": "--MLCSVIQRQTREVSNTMSLDSYYLGFDLSTQQLKCLAINQDLKIVHSETVEFEKDLPHYHTKKGVYIHG--DTIECPVAMWLEALDLVLSKYREAKFPLNKVMAVSGSCQQHGSVYWSSQAESLLEQLNKKPEKDLLHYVSSVAFARQTAPNWQDHSTAKQCQEFEECIGGPEKMAQLTGSRAHFRFTGPQILKIAQLEPEAYEKTKTISLVSNFLTSILVGHLVELEEADACGMNLYDIRERKFSDELLHLIDSSSKDKTIRQKLMRAPMKNLIAGTICKYFIEKYGFNTNCKVSPMTGDNLATICSLPLRKNDVLVSLGTSTTVLLVTDKYHPSPNYHLFIHPTLPNHYMGMICYCNGSLARERIRDELNKERENNYEKTNDWTLFNQAVLDDSESSENELGVYFPLGEIVPSVKAINKR-VIFNPKTGMIEREVAKFKDKRHDAKNIVESQALSCRVRISPLLSDSNASSQQRLNEDTIVKFDYDESPLRDYLNKRPERTFFVGGASKNDAIVKKFAQVIGATKGNFRLETPNSCALGGCYKAMWSLLYDSN--------------KIAVPFDKFLNDNFPWHVMESISDVDNENWDRYNSKIVPLSELEKTLI------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .:.** .: : :. .*:: :.:: ***.: * * **::*:*::: : * :::*: ****.::*. . * .*. * : .* * * * :* * ::* :** : :***:.: **** ** *: . *..:. ***:*.* :*:::* :: :*..**** :*:.: :* * . : .:* . : * : *:::::.* ..* * . :*.: : :..: : .. : :*:.** .:.: .: : *:: :*. .:*.::*: *..* *: : .. .* * : : .. .::..:* ** * . : : * : : ::*.* : : : : : .* * ::: .*:::.*. . . :* .::: .: : : . . . . . * . : : : : ", "identical_positions": 91, "similar_positions": 177, "identity": "14.42%" }, { "cls_id": "homologset.agr.MGI:2142989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A140UHX3-1", "uniprot_id": "A0A140UHX3_RAT", "id": "A0A140UHX3-1", "name": "Condensin-2 complex subunit D3", "aln": "MVGMALKDLGRDLQPWCPLDLSLEWVNTVWDLDFTETEPLDPSVVAEILETGRDAFTKLYGSLFPFATDESGSLESVWSFFTENSISSNTLVALFCHFVQEAHKKSASVQYREYGLRAAGLYFLLLEIPGSVVNQVFHPVMFDKCIQILKKSWPQESNLTQKRKKEHSKSSKANYRRSRKRGKPPRKEDYQVDELSREEEEEE-----EEEIYFSVRDLSQIRDAIFNLLKNFLRLLPKFSLKEKPQSIQTCIEVFVALTSFEPIPHKFLISQARNLSEVKHISELAYYGLYLLCSPVHGEGNKVIGSIFHQMLNVILMLEVGEGSRCAPLAITSHVINCRNQAVQFVSSLVDELQESVFPILGTLLQHICAKVVD--KAEYRTYAAQSLVQLLSKLPSKEYATFIAWLYKYSRSSKIPHRVFTLDVALALLELPERLLDDTVLLEHQKFLKHKFFVQEIIFDRCLDKAPTVRSKALSSFAQCLELSTSNTSENTLEIFINS-TVTGIHSHFGTSLRPSTVLTSQSCRSVQS------STHDSDEQTPPGERRFMTMLRKRTKDEKINVRKSALQVLMSILKHCDILSMEEDLLILQDHCRDPAIS-VRKQALQSLTELVMAKPTCVPVQKAWLMGVIPVVMDYESTVQEKALECLDQLLLQNIKHHRKFHSEDRSQVLAWALLALLTVESQDLSRYLNKAFHIWSKKD-KFSSTFINSVISHTDTERSAPAWMLLSKITCSSPKLDYTKIMESWEKLSREQSPNSNTLGYMLCVIGHIAKHLPKSTQDKITGVIKAKLNGFQWSLELISLSVDTLQGLCRASAKTLREEQELLKRVCGDVLSTCEQHLSNILLKEDGTGNMDEDLVVKCIF-TLGDIAQLCPALVEKRVFLLIQSILASSAHADHLPSSQGTTD-LASQLPFQARSSALPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTVMVDNYIPNISICLKDSDPFIRKQTLILLTNLLQEEYVKWKGSLFFRFVSTLVDSHPDIASLGEFCLAHLLLKRNPTMFFQHFIECIFHFNSYEKHGQYNKFSQSERGKPLFLLKGKTNKEKRMRIYKFLLEHFTDEQRFNVTSKICLNILACFTDGVLPVDMEASELLSDTFDILSSKEIKLLAMRAQASKELLEE-DDVALANVVMQEAQMKIISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMNYLREVMQDYRDEIKDFFAVDRQLASELEYDMKKYTEQLAQEQALTEHANATNVPADGDRVPSQQVAPDLQAVPGAAAA-------------AGAGQADANMPLPLAQSQPSAPGS--SFTPTLPPICEKGPLK-IMSSTRPMSLSTIAILNSVKKAVASKS--RTRSLGALSFNMENGSPENPSSRASSLSLEQESERAVKRVTKRAISTPEKSISNVTFGAGVSYIGTPATSFFTKEKPEEAQEEGNDILCLSLLDKRPPQSPQWNVKSPARSQDNPRSGRRSLRKAPLKTAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQK0-1", "uniprot_id": "CNDD3_MOUSE", "id": "Q6ZQK0-1", "name": "Condensin-2 complex subunit D3", "aln": "---MALQDLGENLQPWCPLGLSLEWVKTVWDLDFTEIEPLDPSIVGEILETGRDAFTKLYGSLFPFATDESGSLESIWTFFTENDISSNTLVALFCHFVQEAHKKSASAQYREYGLHAAGLYFLLLEIPGIVVNQVFHPVMFDKCIQILKRSWPQESNLTQKRKKDHSKSSKDNYRKSRKRGKPPRKEDYQVDELSREEEEEE-----EE-IYFSGRDLCQIRDAIFNLLKNFLRLLPKFSLKEKPQSIQTCIEVFVALTSFEPIPHKFLISQARNLNEVKHISELAYYGLYLLCSPVHGEENKVIGSIFHQMLNVILMLEVGEGSRCAPLAITSQVINCRNQAVQFVSSLVDELQASVYPVLGTLLQHICAKVVD--KAEYRTYAAQSLVQLLTKLPSEEYATFIAWLYKYSRSSKIPHRVFTLDVALALLTLPERELDDTVSLEHQKFLKHKFFVQEIIFDRCLDKAPTVRSKALSSFAHCLELSSSNTSESILEIFINSNLVPGIQNLSNTVLNPSPVLTSRNGYSAQS------RTHNNDEQTLPGERCFMTMLRKRIKDEKINVRKSALQVLMSILKHCDILSMEQDLLILQDHCRDPAIS-VRKQALQSLTELVMAQPTCVPVQKAWLMGVIPVVMDCESTVQEKALECLDQLLLQNIKHHKKFHSADRSQVLAWSLLALLTIENQDLRRYLNKAFHIWSKKD-KFSSTFINSVISHTDTERSAPAWMLLSKITCSSPKLDYTKIIESWERLSREQSPNSNTLGYMLCVIGHIAKHLPKGTRDKITGVIKAKLNGFQWSPELISSSVDALQKLCRASAKTVLEEQGLLKQVCGDVLATCEQHLSNILLKEDGTGNMDEGLVVKCIF-TLGDIAQLCPAIVEKRVFLLIQSILASSAHSDHLPSSQGTTDALDSQPPFQPRSSAMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVSEDVAVRNNVIIVICDLCIRYTVMVDNYIPNISVCLKDSDPFIRKQTLVLLTNLLQEEYVKWKGSLFFRFVSTLVDSHPDIASLGEFCLAHLLLKRNPTMFFQHFIECIFHFNSYEKHGQYNKFSQSERGKQLFLLKGKTNKEKRMRIYKFLLEHFTDEQRFNVTSKICLNILACFTDGILPMDMEASELLSDTFDILNSKEIKLLAMRAQTSKDLLEE-DDVALANVVMQEAQMKIISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMNYLREVMQDYRDEINDFFAVDKQLASELEYDMKKYNEQLAQEQALTEHANATKGPEDSDRVPSAQVAPDLEAVPALAAAPMAAAAAAAPMAAAAAAAGQDNADVPPTQSRPSAPRS--NFTPTLPPISENGPLK-IMSSTRPMSLSTIAILNSVKKAVASKN--RTRSLGALPFNVETGSPENPSSHESSLSLEKESDRTVNHVTKRAISTPENSISDVTFAAGVSYIGTPAT-FFTKEK-HEAQEQGSDILCLSLLDKRPPQSPQWNVKSPARSHGSTRSSRRSLRKAPLKTAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42695-1", "uniprot_id": "CNDD3_HUMAN", "id": "P42695-1", "name": "Condensin-2 complex subunit D3", "aln": "--MVALRGLGSGLQPWCPLDLRLEWVDTVWELDFTETEPLDPSIEAEIIETGLAAFTKLYESLLPFATGEHGSMESIWTFFIENNVSHSTLVALFYHFVQIVHKKNVSVQYREYGLHAAGLYFLLLEVPGSVANQVFHPVMFDKCIQTLKKSWPQESNLNRKRKKEQPKSSQANPGRHRKRGKPPRREDIEMDEIIEEQE--------DENICFSARDLSQIRNAIFHLLKNFLRLLPKFSLKEKPQCVQNCIEVFVSLTNFEPVLHECHVTQARALNQAKYIPELAYYGLYLLCSPIHGEGDKVISCVFHQMLSVILMLEVGEGSHRAPLAVTSQVINCRNQAVQFISALVDELKESIFPVVRILLQHICAKVVD--KSEYRTFAAQSLVQLLSKLPCGEYAMFIAWLYKYSRSSKIPHRVFTLDVVLALLELPEREVDNTLSLEHQKFLKHKFLVQEIMFDRCLDKAPTVRSKALSSFAHCLELTVTSASESILELLINSPTFSVIESHPGTLLRNSSAFSYQRQTSNRSEPSGEINIDSSGETVGSGERCVMAMLRRRIRDEKTNVRKSALQVLVSILKHCDVSGMKEDLWILQDQCRDPAVS-VRKQALQSLTELLMAQPRCVQIQKAWLRGVVPVVMDCESTVQEKALEFLDQLLLQNIRHHSHFHSGDDSQVLAWALLTLLTTESQELSRYLNKAFHIWSKKE-KFSPTFINNVISHTGTEHSAPAWMLLSKIAGSSPRLDYSRIIQSWEKISSQQNPNSNTLGHILCVIGHIAKHLPKSTRDKVTDAVKCKLNGFQWSLEVISSAVDALQRLCRASAETPAEEQELLTQVCGDVLSTCEHRLSNIVLKENGTGNMDEDLLVKYIF-TLGDIAQLCPARVEKRIFLLIQSVLASSADADHSPSSQGSSEAPASQPPPQVRGSVMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTIMVDKYIPNISMCLKDSDPFIRKQTLILLTNLLQEEFVKWKGSLFFRFVSTLIDSHPDIASFGEFCLAHLLLKRNPVMFFQHFIECIFHFNNYEKHEKYNKFPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFADGILPLDLDASELLSDTFEVLSSKEIKLLAMRSKPDKDLLMEEDDMALANVVMQEAQKKLISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMHYLREVMQDYRDELKDFFAVDKQLASELEYDMKKYQEQLVQEQELAKHADVAGTAGGAEVAPVAQVALCLETVP--------------------VPAGQENPAMSPAVSQPCTPRASAGHVAVSSPTPETGPLQRLLPKARPMSLSTIAILNSVKKAVESKSRHRSRSLGVLPFTLNSGSPEKTCSQVSSYSLEQESNGEIEHVTKRAISTPEKSISDVTFGAGVSYIGTPRTPSSAKEK-IEGRSQGNDILCLSLPDKPPPQPQQWNVRSPARNKDTPACSRRSLRKTPLKTAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMQ4-1", "uniprot_id": "Q9VMQ4_DROME", "id": "Q9VMQ4-1", "name": "Condensin-2 complex subunit", "aln": "--MSDFHRIFGDLRVYYEP--NVQWVDVEEWLYGEEAEGSVLQQRAEKFWT------------MAMCLQDGGHQETQLQLLRD--------LSAIIRAMRDENQASYSNTHDNWSNLIG--FSPALGYLTYIYSLVSLVVLPEHVQQAAPQQLNENINMQLALNAATTYLLTLTIPGAKIFGVFDEDVIEQVLKVFRLLEMNNNKSLRAS----------MIWMFFLTICDDLKIVFRYVHFKEHLKTRDRIIRCLLEVLYMN-----------FKMGYQNTCAPGLHGKCFELFSEIANEHNGDVYETLHLIMRQTFPMHVYTDSPQMIAYGRRGAMQSGEHISDWFIQLIDKYPDIVNRILHFYIECVVSNPIKAWKSNDEKVAIGYAAKYDRVLFTKCNKSCADYVLEAVKADDAVGIQIRALDLIEKILLQESEVEWSIFRHEVSDVPREVPLLREVLRCLNDRTLTVRRKAC----QVLILALRQGSPMTKKILQESIRFVQFDDTDVEALAEPSAQQNELRFEKPGIVQYAFSFQGHEQLETEVKNLPQTVYQRFLAADNGLARSAGIALLERLVLVNPLIIYNTNFVKETSLLAVDRLSSVRKSALETIETLLEAYSNCFALICVYCRIWACLMSDEDVALQKLAISSFDRMVLKNIQPLEYSN--EAKHFMPWRIISTLLMTQP--RAYLQERFAVLLERETIVTPRLVNVIISHLSTSMATDAWGLLLFLS-SRITNNMDALIGIFNGLSSYNMKSNQFLALQLITG--CLRNFSKPALNQLFQKLLNALRTGSIWLGIISSAVNLLNQIHHLSTS---QSPTIASEMPYWQLSLLEDLVEGILS--SAQNFQEEYARLQCLLGAYTELIVMVPQDVDNRIVSIVFKYLQECTKLCESEFDSDNER------------------MTNWMIVIAGRLSLRDNHLANSASKLYITILTKNDRPQIINTTLIALNDLGKKHPSILESNFQAILSKLQSKFAMTRVRTFRCVKDVILSGNIKLKGPILISMLAALVDESAEVAREADAFFTRYKKLYNKMLFDHCLKECPFDLN-----DQAILRGVRTNGNYKSPLKGSQMAKKRRLLYNHIMSSMDEN-----------VLLLYFGQLKLLAEKTRDQAFINNPDALIVVQDMLFIMRRICYCTKGMGKEKNSRGEGDNIDEGEDASSEPATPPTRPEAGEATSRGRGRKADMSEEPLKQLERCLRFVEETHRNIVP---VMSPELSHNFESFCRAMAMRFPNYIEFAQPAQFWRQFRSSAKAP--------------------------------------------------------------------------------------------------------RASRSKRRRMEEGEVESHEEHES------ESDSDSELPLDRHKTTP-----------------------------TASRLSQRKTSCDMLVTELIFQPPDW----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : .*: : ::**.. * * * . .* : * :.:. : * *: :: : :: : : :: :: . * : ::. . : * : . * *: :: * :. :: *: : . . : * . :: :: . * . * :: : .:: :: . :**: : : *. :: : :: :. : . : : * * : .* : : :* :: : :.* .* .::. :: ::. *:*: : :: :: : :: :. *:: .. * .: * :: : ::.. : : : * * :: :: .. . : ::. : . :: *:: *** ** : * *: . * ::: :* . :.. * ... . . . .. : :. :: :: :: .*.:.: :* :: : : :: . :* ***.**::: *: * . *. : .: :: * : ::*: *:. :*:::*:**: : : .:.:.* ::: * . **:: * : ::: .:. ::* :*** .*. :: ** ** :: * : :: :: :* : ..: *. * . :::.* : ::: : *. . :** :*: *: : : *:. :. : ..: *: *. :..*: .. . :* :: :: : :: : * *::*:. :: . * ..:. . .... : *: *:*.*:.:.**:.: : * : : *..:*.: ** ::. :::. : * *:.. .: * :*: :.::: . :* **.::: ::::*:*. .::* .: ::: * :* : : ** *.:* : . : ***. ::* :*:.::. : :: :* * : * : .: : :. : * : *: ** :. : .: : . *: . : : . . .*::* . ** * : :*: : .:. :*: ::* : :: : ::: *: .. .* *: :: *. *. .: * **: : .* :** .: . . * * : *. :* ", "identical_positions": 160, "similar_positions": 461, "identity": "10.43%" }, { "cls_id": "homologset.agr.MGI:2143057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1HG60-1", "uniprot_id": "PIF1_RAT", "id": "Q1HG60-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "-------------MPSSTEVATDECDDTELRCRVAVEELSPGGQPR--KRQALRAAELSLGRNERRELMLRLQAPGPEGRPRCFPLRAVRLFTRFAAVGRSTLRLPADGVPRAGSVQLLLSDCPPERLRRFLRTLRLKLAVAPG-PGPASA------RAQLLGPRPRDFVTISPVQPE------ELRRAAATKAPDSALEKRPMESQP----SMEAPR---WPLPVKKLR-------MPSSKPKLSEEQAAVLRMVLKGQS-IFFTGSAGTGKSYLLKHILGSLP----PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCVALAHRPG-VRQGWLNCQRLVIDEISMVEADFFDKLEAVARAVRQQKKPFGGIQLIICGDFLQLPPVTKG--------SQHPRFCFQAKSWRKCVPVTLELTEVWRQ-ADQTFISLLKAVRLGRCSDEVTRQLRATAAHKVGRDGIIATRLCTHQDDVALTNEKRLKELPGDVHSFEAIDS----DPELSRTLDAQCPVGRVLQLKLGAQVMLVKNLAVSRGLVNGARGVVVGFESEG-----------------------------------------------------------------------------------------------------------RGLPRVRFLCGIT----EVIRTDRWTVQVTGG-QYLSRQQLPLQLAWAMSIHKSQGMSLDCVEISLGRVFASGQAYVALSRARSLQGLRVLDFDPTVVRCDSRVLQFYATLRQGRG------LSLESQD----DEEASSDLENMDPNL----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80SX8-1", "uniprot_id": "PIF1_MOUSE", "id": "Q80SX8-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "MRSGLCTPAEALEMPSSTEAATDECDDAELRCRVAVEELSPGGQPR--KRQALRAAELSLGRNERRELMLRLQAPGPTGRPRCFPLRAVRLFTRFAATGRSTLRLPTDGVPGAGSVQLLLSDCPPERLRRFLRTLRLKLAVAPG-PGPASA------RAQLLGPRPRDFVTISPVQPE------ELQRAAATKAPDSALEKRPMESQT----STEAPR---WPLPVKKLR-------MPSTKPKLSEEQAAVLRMVLKGQS-IFFTGSAGTGKSYLLKHILGSLP----PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCMALANRPG-VRQGWLNCQRLVIDEISMVEADFFDKLEAVARAVRQQKKPFGGIQLIICGDFLQLPPVTKG--------SQQPQFCFQAKSWRRCVPVILELTEVWRQ-ADQTFISLLQAVRLGRCSDEVTRQLRATAAHKVGRDGIVATRLCTHQDDVALTNEKWLKALPGDVHSFEAIDS----DPELSRTLDAQCPVSRVLQLKLGAQVMLVKNLAVSRGLVNGARGVVVGFESEG-----------------------------------------------------------------------------------------------------------RGLPRVRFLCGIT----EVIRTDRWTVQVTGG-QYLSRQQLPLQLAWAISIHKSQGMSLDCVEISLGRVFASGQAYVALSRARSLQGLRVLDFDPTVVRCDSRVLHFYATLRQGRG------LSLESQD----DEEANSDLENMDPNL----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H611-1", "uniprot_id": "PIF1_HUMAN", "id": "Q9H611-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "-------------MLSGIEAAAGEYEDSELRCRVAVEELSPGGQPR--RRQALRTAELSLGRNERRELMLRLQAPGPAGRPRCFPLRAARLFTRFAEAGRSTLRLPAHDTPGAGAVQLLLSDCPPDRLRRFLRTLRLKLAAAPG-PGPASA------RAQLLGPRPRDFVTISPVQPE------ERRLRAATRVPDTTLVKRPVEPQAGAEPSTEAPR---WPLPVKRLS-------LPSTKPQLSEEQAAVLRAVLKGQS-IFFTGSAGTGKSYLLKRILGSLP----PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCVALAQRPG-VRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVRQQNKPFGGIQLIICGDFLQLPPVTKG--------SQPPRFCFQSKSWKRCVPVTLELTKVWRQ-ADQTFISLLQAVRLGRCSDEVTRQLQATASHKVGRDGIVATRLCTHQDDVALTNERRLQELPGKVHRFEAMDS----NPELASTLDAQCPVSQLLQLKLGAQVMLVKNLSVSRGLVNGARGVVVGFEAEG-----------------------------------------------------------------------------------------------------------RGLPQVRFLCGVT----EVIHADRWTVQATGG-QLLSRQQLPLQLAWAMSIHKSQGMTLDCVEISLGRVFASGQAYVALSRARSLQGLRVLDFDPMAVRCDPRVLHFYATLRRGRS------LSLESPD----DDEAASDQENMDPIL----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV90-1", "uniprot_id": "PIF1_DANRE", "id": "Q7ZV90-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "--------------------MLGQMEPAELQCTVAVERLNPAGQAI--KRQLIRKGTVTLGRNEFQEMILRVHDG---KAPQNFMLRDFQLFTRFAKDGKCTVKFVPENT------QVLVSDCPPDRLKMFLKTLSIKHQASQS-SKPLSD------REKLRAGLPRAFETVSPLQLKDVEKANELRSRVNAPMQPRCLAERPVNKVLGDRKQVKRPRPDCDASPVKALHPNKKPVLVLPVAQKLSKEQTAVLNAVLSGKN-VFFTGSAGTGKSFLLKRIVGSLP----PKSTYATASTGVAACHIGGTTLHSFAGIGSGSAPLEQCIELAQRPG-VLRHWTSCKHLIIDEISMVEAEFFDKLEAIARSIRRSTEPFGGIQLIVCGDFLQLPPVTKG--------KEKANFCFQSRSWRKCIHMNMELMEVRRQ-TDKTFISLLQAVRVGRVTEEVTAQLLKSANHCIERDGILATRLCTHKDDVELTNENKLKQLPGVVRMYEAVDS----DPMLVQTIDAQSPVSRLLQLKVGAQVMLTKNLDVQRGLVNGARGVVVDFQPGN-----------------------------------------------------------------------------------------------------------QGLPRVRFLCGAV----EVMKRERWMFKAPGG-LYLSRQQLPLKLAWAISIHKSQGMTLDCVEISLARVFESGQAYVALSRARSLEGLRVMDFDPRVVQANQDVLIFYKRLRKERL------LMQSSMN----DFVGQSNKENSRW------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQR3-1", "uniprot_id": "Q9VQR3_DROME", "id": "Q9VQR3-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "----------------------MDLNDAVLTCAVNMEWTNAVGITG--RKLAYKTATLRLVRNDLRELFVEVTPEK--LKPLKFKLKDLMVHKKFMSEGKATFNFKAEKC------TLYLSNAPPGTLMFFLRTIFVKMNGNEGGSQPDDATLQKKLREHLMSGKPSSFNDVSPVTTA---EMILARKKAGLLSKGSVTTPSPQGAKKRRFEELKEEKERGTMPAAKKLYAS-----TTDESLRLSEEQMEVLRACTSGKS-VFFTGSAGTGKSFLLRRIISALP----PDGTVATASTGVAACLIGGTTLHAFAGIGGGDATMQRCLELASRPA-NAQTWRKCKRLIIDEISMVDGQFFEKIEAVARHIRRNDRPFGGIQLILCGDFLQLPPVIKGDFGAAPTATPQQRFCFQSSAWETCIQCVYELKQVHRQ-SDPEFVKILNHLRIGHVNDSITSRLAATSKQKIEGNGILATQLCSHTNDANSINESKLENLDGDKILFKADDS----DASMTRTLDQQIQAPSQLYLKVNAQVMLLKNINISNGLVNGARGVVVRMEKD--------------------------------------------------------------------------------------------------------------LPVVRFKNNQE----YVCKHERWIIKTASG-NHITRRQVPLKLAWAFSIHKSQGLTLDCVEMSLSKVFEAGQAYVALSRAKSLQSIRILDFDAKQVWANPHVLQFYKGFRRKLMDTTMIPLGPKNKDKKPGDKAANSALAKLKKSLINKPLVSIS-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07271-1", "uniprot_id": "PIF1_YEAST", "id": "P07271-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "---MPKWIRSTLNHIIPRRPFICSFNSFLLLKNVSHAKLSFSMSSRGFRSNNFIQAQLKHPSILSKEDLDLLSDSDDWEEPDCIQLETEKQEKKIITDIHKEDPVDKKPMRDKNVMNFINKDSPLSWNDMFKPSIIQPPQLISENSFDQSSQ-----KKSRSTGFKNPLRPALKKESSFDELQNNSISQERSLEMINENEKKKMQFGEKIAVLTQRPSFTELQNDQDDSNLNPHNGVKVKIPICLSKEQESIIKLAENGHN-IFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKD-------PNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRP-LPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDAT--LVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSDGEESAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVKTDDEVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADEQVKKRKLDYAPGPKYKAKSKSKSNSPAPISATTQSNNGIAAMLQRHSRKRFQLKKESNSNQVHSLVSDEPRGQDTEDHILE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38766-1", "uniprot_id": "RRM3_YEAST", "id": "P38766-1", "name": "ATP-dependent DNA helicase RRM3", "aln": "----------MFRSHASGNKKQWSKRSSNGSTPAASASGSHAYRQQTLSSFFMGCGKKSAAASKNSTTIIDLESGDEGNRNITAPPRP-RLIRNNSSSLFSQSQGSFGDDDPDAEFKKLVDVPRLNSYKKSSRSLSMTSSLHKTASASTTQKTYHFDEDETLREVTSVKSNSRQLSFTSTINIEDSSMKLSTDSERPAKRSKPSMEFQGLKLTVPKKIKPLLRKTVSNMDSMN--HRSASSPVVLTMEQERVVNLIVKKRTNVFYTGSAGTGKSVILQTIIRQLSSLYGKESIAITASTGLAAVTIGGSTLHKWSGIGIGNKTIDQLVKKIQSQKDLLAAWRYTKVLIIDEISMVDGNLLDKLEQIARRIRKNDDPFGGIQLVLTGDFFQLPPVAKKD------EHNVVKFCFESEMWKRCIQKTILLTKVFRQ-QDNKLIDILNAIRYGELTVDIAKTIRNLNRDIDYADGIAPTELYATRREVELSNVKKLQSLPGDLYEFKAVDN---APERYQAILDSSLMVEKVVALKEDAQVMMLK-NKPDVELVNGSLGKVLFFVTESLVVKMKEIYKIVDDEVVMDMRLVSRVIG----------------------------------------NPLLKESKEFRQDLNARPLARLERLKILINYAVKISPHKEKFPYVRWTVGKNKYIHELMVPERFPIDIPRENVGLERTQIPLMLCWALSIHKAQGQTIQRLKVDLRRIFEAGQVYVALSRAVTMDTLQVLNFDPGKIRTNERVKDFYKRLETLK-------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : . . . :: . . . *: ** ::. . :. :*:********* :*: :: * . *****:** *** *:* ::*** *. : * *::*****::.::::*:: :** :*:. *******:. ***:***** * .*.*:: *. : * :* ** * ::.:*: :* *. . : : * .:.* : :. * *. * * ::* *. : . . : ** .****: * ****: * *: : :* **: . : : : .. : * *:** *.*::****:** :: :::.* ::* **.******* : : :::::** : . * ** : ", "identical_positions": 121, "similar_positions": 121, "identity": "13.78%" }, { "cls_id": "homologset.agr.MGI:2143099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q569A3-1", "uniprot_id": "CK087_RAT", "id": "Q569A3-1", "name": "Uncharacterized protein C11orf87 homolog", "aln": "MSARAPKELRLALPPCLLNRTFASHNASGGSNAGIRSSGAGG-GTCITQVGQQLFQSFSSTLVLIVLVTLIFCLIVLSLSTFHIHKRRMKKRKMQRAQEEYERDHCSGSHGGGGLPRAGVQAPTHGKETRLERQPRDSAFCTPSNATSSSSSS---PGLLCQGPCAPPPPPPVPSPHGAHAASSCLDTPGEGLLQTVVLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32M26-1", "uniprot_id": "CK087_MOUSE", "id": "Q32M26-1", "name": "Uncharacterized protein C11orf87 homolog", "aln": "MSARAPKELRLALPPCLLNRTFASHNASGGSSAGLRSSGAGG-GTCITQVGQQLFQSFSSTLVLIVLVTLIFCLLVLSLSTFHIHKRRMKKRKMQRAQEEYERDHCSGSHGGGGLPRAGVQAPTHGKETRLERQPRDSAFCTPSNATSSSSSSSSSPGLLCQGPCAPPPPLPAPTPQGAPAASSCLDTPGEGLLQTVVLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUJ2-1", "uniprot_id": "CK087_HUMAN", "id": "Q6NUJ2-1", "name": "Uncharacterized protein C11orf87", "aln": "MSARAPKELRLALPPCLLNRTFASPNASGSGNTGARGPGAVGSGTCITQVGQQLFQSFSSTLVLIVLVTLIFCLIVLSLSTFHIHKRRMKKRKMQRAQEEYERDHCSGSRGGGGLPRPGRQAPTHAKETRLERQPRDSPFCAPSNASSLSSSS---PGLPCQGPCAPPPPPPASSPQGAHAASSCLDTAGEGLLQTVVLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************ ****...:* *..** * *******************************:**********************************:*******.* *****.************.**:****:* **** *** ********** *..:*:** ********.***********", "identical_positions": 170, "similar_positions": 18, "identity": "85.0%" }, { "cls_id": "homologset.agr.MGI:2143103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH79-1", "uniprot_id": "ANO10_MOUSE", "id": "Q8BH79-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MRVTLSTLDTCESSFTPLVVIELAQDVKDETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEKETLENQ----NLYLVGASNVRLLLGAEAVGLVKECTDAAMRAFTYGTRHNFKGFHDNNNDFLTMAECQFIIKHELENLRARDEKMIPGY----PQAKLYPGKSLMRRLLTSGIVTQVFPLHDTEALKKLEDTWYTRFALKYQPIDSIRSYFGETIALYFGFLEYFTFALIPMAIIGLPYYLFVWED-----------------------YDKYVIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPRPGFHGVLGINSVTGREEPLYSSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEDWALSLHEDSGSEWTSLLLYVPSIVYAVVIEIMNRLYRYAAEFLTSWEN--HRLESAYQN----HLVLKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQVVESLLPYWLQRKYCARVKRK----VQALKSEVDTTLYEQVLLEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFAEPSAS----------IGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPES----------------KTDLVLIVVAVEHALLALKFILAFAIPDKPRHIQQKLARLEFESLEALKQQQMKLVAENLKEEYQEDGKEAT------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LE79-1", "uniprot_id": "A0ABK0LE79_RAT", "id": "A0ABK0LE79-1", "name": "Anoctamin", "aln": "MFSWFLKEKETAERKHWSGSPGSRACRRMPPSRTESSLSALELCGSQGLCHGYPVATSQSCPWETETSSQPYGMELSRLLPLRAPVIIRVGKPHPEAPGRAILSPDSQIEEEEEEAEEEEKKEEERRRRKRKKKKRKKRRKKKRRLLRSKRLSLSKMKGILSTVDTCESSFTPLVVIELAQDVKEETKEWLKSRIISPKKDGGAQLLFRPLLNKYEKETLENQ----NLYLVGASNIRLLLGAEAVGLVKECTDGAMRAFTYRTRHNFKGFHGNNDDFLTMAECQFIIKHELENLRARDEKMIPGY----PQAKLYPGKSLMRRLLTSGIVTQVFPLHDTEALKKLEDTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWED-----------------------YDKYVIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPRPGFHGVLGINSVTGREEPVYSSYKRQLRTYLVSLPFVCLCLYFSLYVMMIYFDMEDWALSLHEDSGSEWTSLLLYVPSIVYAIVIEIMNRLYRYAAEFLTSWEN--HRLESAYQN----HLVLKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQVVESLLPYWLQRKYCARVKRK----VRALKSDVDTTLYEQVLLEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSAS----------IGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPES----------------KTDLVLIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVAESLKEESQEEEKEAAACRMPATLPQPELRNNCITPGQGGDASLS-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NW15-1", "uniprot_id": "ANO10_HUMAN", "id": "Q9NW15-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MKVTLSALDTSESSFTPLVVIELAQDVKEETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEQETLENQ----NLYLVGASKIRMLLGAEAVGLVKECNDNTMRAFTYRTRQNFKGFDDNNDDFLTMAECQFIIKHELENLRAKDEKMIPGY----PQAKLYPGKSLLRRLLTSGIVIQVFPLHDSEALKKLEDTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWED-----------------------YDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGVLGINSITGKEEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYVPSIIYAIVIEIMNRLYRYAAEFLTSWEN--HRLESAYQN----HLILKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQIMESFLPYWLQRKHGVRVKRK----VQALKADIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSAN----------IGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPES----------------KADLILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEPMESGKEKAT-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8U5-1", "uniprot_id": "ANO10_DANRE", "id": "Q4V8U5-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MQLGLSVSDSDASPFTPLAVLELAHDTKAEAIAWLLNRIRDKQRNGGAELLVDQLLFPAQDGQKPNP----NVFVVGSTLQRLLSGAEDVGLFKEFQDGTMRGFTYANRESFKDFEGDGEGFLGDAECQYIVKHELDTLRAKNEEYIPGY----PKYKLYPGKSIVRRLQSKGVLVQYFPLHNKEDLKRLSFSWYKKIKLSFQPLDDIRSYFGEGLGLYFGFLEYFTFALIPMALIGIPYYLFDWED-----------------------YDKYVLFAVFNLVWSTVFLEVWKRCSATLAYSWGTLGRKKAFEEPRAGFHGPLGLNPVTGREEPIYPSSKRHLRIYLVSVPFVLLCLYLSFYVMMVYFDMEFWAISIYHENPNFATSVLLFVPSIIYAVVIEIMNLLYRYAAEFLTDWEN--HRLESSFQN----HLVPKVLVFNFVNCFASLFYIAFVMQDMVLLRQSLATLLITSQILNQVMEAFLPYWLQRRRNKRVYKR----MRRLMGDKELPLLEQIQLETEMNTYLGTFDDYLEQFLLFGYVSLFSCVHP-LAAVLVVLNNITEVYSDAFKMCHVFKRPFSEPAAN----------IGVWQLAFETMSIIAVVTNCALIALSPQVKAYFPES----------------DAQLILTVVAIEHVLLAFKFILAFVIPDVPKHIQVKLSKLDFESLEALKKRKILEVAET-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P6G3-1", "uniprot_id": "A0A8M9P6G3_DANRE", "id": "A0A8M9P6G3-1", "name": "Anoctamin", "aln": "MAGSRTQIYQTAEQDCSLCWKKNENAPPHPKAREERRSSAFFFSPSKAAHGLDLNRFQTGQWGECGHQQHSPESDRRSRLFDRSQTGFLEG-------------------HSSAQFCSNPNQTQLMQLIKLQRDNMTSQKEPQEGHSTSTKVTGPSSWSKVSCPCCTSTQIEPLVLIQLAESVQPITKQWIMSVIAAPVKAGGAQLLVHP-------GEDMKG----DMIVVAAPRCTLHRVTEELGLCKTYQDGDMKAFSFEDRDNFCNID-DTQQFLTLAERQFIVKHEMDLMKALEDQRIPGIP--APAGKLKARESILQKLEKAGLIRSITPLHDQERLADLGKQWYSQKSLWGQPLDYIHNYFGGTIAYYFSFLDFYTLSLFPPAILGIFITFFLPSANFSTAIETDSNASSKISDDDHLSVSSYMVQAVFSMLWSTIFMELWKRRSASLSYHWGTFNLAEQFQEPRPGFHGEIGTNPVTGRLEPLFPDWKRKMRMGLVSVPVVGFFLGLVILGMAGFYICERLVSSWHKESGSYFTAPLLYLPSIAHIVYTNVLGNVYRNVALKLTEAEN--HREESSFDY----HHTTKVLVFTFFNNFAVLFHIAFFKEDMPLLRKRLSSLLIVTQVVGQFTEVVVPFLVDR----FLTSA----NRNLKED--DPEVDHLQAQGSLPAFPGLFAEYIELLVQFGYLSLFSCVYP-LTAPLLLLNNLTEIRTDAYKLCKLFNKPFSAPVAN----------LGVWQLAFEVLSFISVISNCWLLLLSPRVKEWTQEAGLS-------------SSQVIVIAVIVEHVLLIVKMILAFIIPDEPDWLQVKREQIEYNSMQALKKQRIKSTRVDGKLQKAKMGE---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97132-1", "uniprot_id": "O97132_DROME", "id": "O97132-1", "name": "Anoctamin", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSEDAKSPGPRTRNIIENQLFRRQRSLKLEALQRQRTLDSNDGVEGLGADTEPFDKTHIVIIFTEKAKLRHCQDVEKIIQEFGIQTTLEIVGKTEKYLYLSASVDTLLRLADAAELEKMTTTHSMQKFNHGCISDFLLPGMGKEQILRYCEIPVLIKDVIQDG--------------------------IKSYVQKGYIEDMFPLHDILYLERFNWNLKR----TKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVFDLNIS---------------------------LVCSFYVVWTTIFLELWKRKCAGYSYRWGTIEMS-SLDKPRSAYTGQLKPDPITGKMTLHYPMRYTYLQMYCISYPVVLGCVVAAGWFALYQFQIEAEVLADFGPD-----SWLLYVPVIVQSVLIAIFSWAYEKLATFLTNLEN--HRTRSQYDR----HRVNKLMLFEIVNNFFSQFYIAFVLHDLRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEFRHREVAEEKLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAP-FAAIGALLNNVFAVHIDMWKLCNIFKRPFARRAKN----------IGAWQLAFELLSVMSLLSNCGLLFLQPNVKDFFSHWLP---------------SVPDLSFVIFEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFKAEANKMA----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38250-1", "uniprot_id": "IST2_YEAST", "id": "P38250-1", "name": "Increased sodium tolerance protein 2", "aln": "----MSQTITSLDPNCVIVFNKTSSANEKSLNVEFKRLNIHSIIEPGHDLQTSYAFIRIHQDNAKPLFSFLQNLDFIESIIPYHDTELSD-------------DLHKLISISKSKILEAPKQYELYNLSNLTNNPKQSLYFAFLQNYIKWLIPFSFFGLSIRFLSNFTYEFNSTYSLFAILWTLSFTAFWLYKYEPFWSDRLSKYSSFSTIEFLQDKQKAQKKASS-VIMLKKCCFIPVALLFGAILLSFQLYCFALEIFIKQIYNGPMISILSFLPTILICTFTPVLTVIYNKYFVEPMTKWENHSSVVNAKKSKEAKNFVIIFLSSYVPLLITLFLYLPMGHLLTAEIRTKVFNAFSILARLPTHDSDFIIDTKRYEDQFFYFIVINQLIQFSMENFVPSLVSIAQQKING-------------PNPNFVKAESEIGKAQLSSSDMKIWSKVKSYQTDPWGATFDLDANFKKLLLQFGYLVMFSTIWPLAPFICLIVNLIVYQVDLRKAVLYSKPEYFPFPIYDKPSSVSNTQKLTVGLWNSVLVMFSILGCVITATLTYMYQSCNIPGVGAHTSIHTNKAWYLANPINHSWINIVLYAVFIEHVSVAIFFLFSSILKSSHDDVANGIVPKHVVNVQNPPKQEVFEKIPSPEFNSNNEK--ELVQRKGSANEKLHQELGEKQPASSANGYEAHAATHANNDPSSLSSASSPSLSSSSSSSKTGVVKAVDNDTAGSAGKKPLATESTEKRNSLVKVPTVGSYGVAGATLPETIPTSKNYYLRFDEDGKSIRDAKSSAESSNATNNNTLGTESKLLPDGDAVDALSRKIDQIPKIAVTGGENNENTQAKDDAATKTPLIKDANIKPVVNAAVNDNQSKVSVATEQTKKTEVSTKNGPSRSISTKETKDSARPSNNNTTTTTTTDATQPHHHHHHHRHRDAGVKNVTNNSKTTESSSSSSAAKEKPKHKKGLLHKLKKKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : * :. * . . : . ::. : : : : : : : . : : : : :. :: : * . : . : : : . * . :* .. :: : : . . :. . . : : . :* : * : : *. . .. * .: : * ::::: .. . : :. : : : :: ::: .: : . : : . * :. * ::: :. * . ::*:: . :* : :* :. :: : :. : : .: .. : : . . :*. . . ", "identical_positions": 17, "similar_positions": 129, "identity": "1.74%" }, { "cls_id": "homologset.agr.MGI:2143107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV36-1", "uniprot_id": "S22AD_RAT", "id": "B2GV36-1", "name": "Solute carrier family 22 member 13", "aln": "--------------------------------------------------------------------MAQFAQVMAEVGDFGRFQVRLTILMGIPNFLSAFFVFSQVFMVLDEAHYCSVSWVKNHTFNLSAAEQLAVSIPNDTAGRPESCLMFRPPPDNASLE-DILSHRFNETQACDSGWDYPENR--PPSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRPSLLMQLLLSGIASMATAFVSSFELYMTLRFALATANAGFLLSSNVLLSEWVGTSRRTRAMVLAQSNFALG-LMALAGLAYGVRNWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGR----TEEAKQLVQKAALVNGR--PLASELLNQLVP--------EKTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLT-QVIFGVVEVPARLSSIPMMEKLGRKWSQLCTLT------LAGVMCVIIIFIPGDLPTVATALAVVG---KFASSAAFTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPETRGQTLKDTLQDLE-----------------------QGQPPRSYKTAPQR----------KDVEASGR----TSSARVAVVRSSYF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z8A7-1", "uniprot_id": "D3Z8A7_RAT", "id": "D3Z8A7-1", "name": "", "aln": "--------------------------------------------------------------------MAQFAQVMAEVGDFGPFQVRVTILMGIPNFLSAFFVFSQVFMVLDEAHHCSVSWVKNHTFNLSAAEQLAVSIPNDTAGRPESCLMFRPPPDSASLE-DILSHRFNETQACDSGWDYPENR--PPSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRASILLQVLLSGITGVATAFVPSFELYMVLCFFSAIAVAGYMMSTMILVSEWVGPSWRTRAMVLAQSNFALG-LMALAGLAYGVRNWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGR----TEEAKQLVQKAALVNGR--PLASELLNQLVP--------EKTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLT-QVIFGVVEVPARLSSIPMMEKLGRKWSQLCTLT------LAGVMCVIIIFIPGDLPTVATALAVVG---KFASSAAFTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPETRGQTLKDTLQDLE-----------------------QGGPHGEHRLLGRTSVAGVCLAVFRSFTEEGRPSLNVGSILLAMALNSINK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A4L0-1", "uniprot_id": "S22AD_MOUSE", "id": "Q6A4L0-1", "name": "Solute carrier family 22 member 13", "aln": "--------------------------------------------------------------------MAQFAQVMAEVGDFGRFQVRLTILMGIPNFLAAFFIFGQVFMVLDEAHHCSVSWVKNHTFNLSAAEQLAISIPNDTAGRPESCLMFRPPPDSASLE-DILSHRFNETQACDSGWDYPENR--PQSLKKEFDLVCDRKNLKKTSQSVFMAGLLVGALVFGPVCDWIGRRPSLLMQVLLSGITSMATAFVSSFELYLALRFVLATANAGFLLSTNVLISEWVGPSWRTQAVVLAQSNVALG-QMVLAGLAYGVRNWRLLQITGTAPVLLLFFYFWVLPESPRWLLSQGR----TEEAKQLVQKAALVNGR--PLSPELLNQLVP--------EKTGPSGNALDLFRHPHLRKVTLILIAVWFVDSLVYYSLSFQVGDFGLDIYVT-QLIFGAVEMPGRFLSVLMMEKLGRKWSQLCTLT------LAGIMYIIIIFIPGDLPTVVTVLAVVG---KFASAAAFTISYVYTAELFPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHQAIPMVIFGSLPIGAGLLCALLPETRGQTLKDTLQDLE-----------------------QGLPAGSHKTAPQR----------QDMEALGR----TSSVRVAVVKSSYF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y226-1", "uniprot_id": "S22AD_HUMAN", "id": "Q9Y226-1", "name": "Solute carrier family 22 member 13", "aln": "--------------------------------------------------------------------MAQFVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQ-DILSHRFNETQPCDMGWEYPENR--LPSLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLG-QMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGR----MDEAIQLIQKAASVNRR--KLSPELMNQLVP--------EKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLT-QLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLV------LGGLMCIIIIFIPADLPVVVTMLAVVG---KMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLKDTLQDLE-----------------------LGPHPRSPKSVPSE----------KETEAKGR----TSSPGVAFVSSTYF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YVM2-1", "uniprot_id": "A0A8M6YVM2_DANRE", "id": "A0A8M6YVM2-1", "name": "", "aln": "--------------------------------------------------------------------MIDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEKQLNLTVPLDSKGQYESCKMFTP--VEMDIE-DIEHYGINTTTSCIDGWVYKAPKD-SSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALRFVVGTTISGISINTFVLGTEWCGSAKRALFTILSHCFFAIG-LMLLSGVAYGIRNWRVLQLVLSAPVGLFFIYYWILPESARWLLTQGK----LDSAKREILKAARINGR--KVSENLLDKMEA--------ENTAKSSTMIDLFRVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLT-QLIFGMAEFPARLSCFPLIQRFGRRICQSVVLL------LGGTACLIIPAIPAKYPIVVTVIAVIG---KFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDLQD-HTDIP-----------------------ADESMTVTEVKLER---------WGRRRGWDR----ERSTSQDFKSGRL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X1WCW3-1", "uniprot_id": "X1WCW3_DANRE", "id": "X1WCW3-1", "name": "", "aln": "--------------------------------------------------------------------MANFGEILEAIGDFGLFQKLLLFALCFPNLILPFQLSSLVFNHADTNHHCNTDWILKADPNLTKEEQLNLTLPRLSDGSFNPCQMYKP--VDWNLS-AIQEYGLNQTTTCTDGWVHNDTIY-EATIVTDFDLVCENVNIFRGAQTVFFAGVLVGAILFGPFSESFGRKRATQIPMVLMLIFTVVTGLSPNFYVYLVSQFINGVGLGGFRINSIILASEWIGVAQRSYAACLSQVLAALG-QVMFLAVVYFVRDWRLDQFIMAGPIGIVVIYIWFLPESARWLLDRGR----TKDAKKLIQKAAAVNKR--AVPESLVEEVLK--------EKPVEKGGIKILFGSRVLRKYFLAITFAWCALNLAYYSLSLNVGKFGLDIFLT-QLIFGLSEIPVHFLCMWSLEVVGRKPSLIVSLV------LGGCLCLLTVAVPQNSSIAIAVLATCG---RFLMNAAGSVCNVYFQELFPTSIRQTATGLGSTAARAGSMLSPVVNMLEIFHFSIPMVVISSLALASGVTAFLLPETRRTELPASTEEAE-----------------------GKRKPKLTSPATRD--------------------------CEDTKVTKL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRT4-1", "uniprot_id": "Q9VRT4_DROME", "id": "Q9VRT4-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MEGQAKQAYFVNEAFTYEEPPQGGGGGGADALHRRKSGGGNKELQLDMGGFKKGQEMAGGNGSDSLPPSMDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDG---LDVEARLALSIPMTN-GEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGK----VDKAVGILKKLEKGNGR--QVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFT-FTLACFTELPADTLLTVILDRFGRRWLACSSMV------LSGVFSLLATVVPVG--IYSAALAIMG---RFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEKRNADVEEVRSQAFVRGTQTGASLNASTGGELRSSILRRSTKSRNSTKL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDS0-1", "uniprot_id": "Q9VDS0_DROME", "id": "Q9VDS0-1", "name": "Solute carrier family 22 member 13", "aln": "----------------------------------------------------------MVNPSPARGGESTAPHILPNEMENDVDKRIATPPPAPAGSDVIADVVGDFGIWQLRTILIIFLCKIPAAWFMACIIFTGPELYPGSEFTCDTSYLTSSSNSSFSIS-DNQCYVLDESTGTSSECEQFNYVSSFDSLIMQFNLVCLRDIFVAWTQYWHLFGVLVGGVMGTKMMLGISPRSTYCVGAVAQILCGVVTGYARDFSLHCAFRCLSAVCCAIMFTAGQAIFADITAGMHRIGAIILYDTFWSIG-VILLPGLSSFFNSWSLIYVGITFPTIMLILLLYWTPDSPRWLLRHAADRFSIDNVEQILREGAAINDRSFKIPPDFRQQLEQLSER---LKAQPPPAPWTELWKGKRAKTHMVAAHLALAFFVINFMGMLLNIRSFGRDYLVPNTIAMGFSEIIGCFLALHFTLKHNKWKWQCAGVFNILAGILGCMGWIFTNADSMDADLKVSLWMIIATIPKAAVSCAQSMILACMNELMPANKKQLFVFSVVTWARVWLLSAPFFNVLRKIDTAMSLTSYCVFSILGGICTSLLLTPR-LSVSPVVPHLE------------------------QRNTKEQSPLNAP----------------------VWTVESDVNNTRL--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : . : . . . : : . : . : . . :: : : ** :* .: * :** :: . . : . : : .. .: . . : : . * : * : : . .* : . : * : .: : *:*.***: :. ... : : * * :. . : . : *: : : : : . :: .:* * .. *. .: : *. :: . : . : : .: *: *: : . : :*.. * ::.: : : .* ** . : . ", "identical_positions": 29, "similar_positions": 114, "identity": "4.23%" }, { "cls_id": "homologset.agr.MGI:2143132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K124-1", "uniprot_id": "PKHO2_MOUSE", "id": "Q8K124-1", "name": "Pleckstrin homology domain-containing family O member 2", "aln": "MEEESIKEGSEKPRGARTADKAGWIKKSSGGLLGLWKDRYLLLCQAQLLVYENEDEQKCVETVELGSYEKCQDLRTLLKRKHHRFILLRSP--GNKVSDIKFQAPSGEEKESWIKALNEGINRGKNKAFDEVKVDKTCALEHVTRNRVRGGQRRRPPTRIHLKEVASAASDGLSRLDLD---------------------------------------VPDSGPPVFAPLSDISEDQPQEPPR-----------------ALMPPVKPS-----PGPETSAVEDSKETPAGERALTPDS-------------ASSGANPESQEDAETPAKEDSDVKSLPNSTLSEKLK---------------------VSWENPSPEKPSAPESAQLS---SSETPEATP------------------RESKKPPAPPPK-------------------ILSEKMKACMSGVD----------------------------------ASGSSQSSEAPETTSPEPTQVSVNGMDDGPESA----------------------------LQAMGIPGPAPEDAAASPALPFSDLPSQFHPRSSSLGDLLRESPQ----HPRLPKEKLYRAQLEVKVASKQTEKLLNQVLGSEPP---PVCAESLLSQAVEQLRQATQVLQEMRDLGELNQETPGLVQKRKELVTLYRRSAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9K4-1", "uniprot_id": "D3Z9K4_RAT", "id": "D3Z9K4-1", "name": "", "aln": "MEEESIKEGTEKPRGARTADKAGWIKKSSGGLLSLWKDRYLLLCQAQLLVYENEDEQKCVETVELGSYEKCQDIRTVLKRK-HRFILLRSP--GNKVSDIKFQASSGEEKESWIKALNEGINRGKNKAFDEVKVDKTCALEHVTRNRVRGGQRRRPPTRIHLKEVASAASDGLSRLDLD---------------------------------------VPDSGQPVFAPLSDISEDQPQEPPQ-----------------ALMPPVKPS-----PVPETSGAEDSQETPAGERALTPLS-------------ESSEANSESQEDAETLAKEDSDFKRLPDSALSEKLK---------------------VSWENPSPEEPSVSERAQLS---SSETPEAAP------------------RESKKPPAPPPK-------------------ILSEKMKACMSGMG----------------------------------DSGPSQSSEGPETTSPGPTQVSVNGVDDGPETA----------------------------SQAVGTAGPAPEDEAASPEVPSWGLPSQFHPRSSSLGDLLRESPQ----HPRLPKEKLYRAQLEVKVASKQTEKLLNQVLGSEPP---PVCAESLLSQAVEQLRQATQVLQEMRDLEELNQESPGLVQKRKELVTLYRRSAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TD55-1", "uniprot_id": "PKHO2_HUMAN", "id": "Q8TD55-1", "name": "Pleckstrin homology domain-containing family O member 2", "aln": "MEEEGVKEAGEKPRGAQMVDKAGWIKKSSGGLLGFWKDRYLLLCQAQLLVYENEDDQKCVETVELGSYEKCQDLRALLKRK-HRFILLRSP--GNKVSDIKFQAPTGEEKESWIKALNEGINRGKNKAFDEVKVDKSCALEHVTRDRVRGGQRRRPPTRVHLKEVASAASDGLLRLDLD---------------------------------------VPDSGPPVFAPSNHVSEAQPRETPR-----------------PLMPPTKPF-----LAPETTSPGDRVETPVGERAPTPVS-------------ASSEVSPESQEDSETPAEEDSGSEQPPNSVLPDKLK---------------------VSWENPSPQEAPAAESAEPSQAPCSETSEAAP------------------REGGKPPTPPPK-------------------ILSEKLKASMGEMQ----------------------------------ASGPP---------APGTVQVSVNGMDDSPEPAK--------------------------PSQAEGTPGTPPKDATTSTALPPWDLPPQFHPRCSSLGDLLGEGPR----HPLQPRERLYRAQLEVKVASEQTEKLLNKVLGSEPA---PVSAETLLSQAVEQLRQATQVLQEMRDLGELSQEAPGLREKRKELVTLYRRSAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5N8-1", "uniprot_id": "A0ACD6B5N8_DANRE", "id": "A0ACD6B5N8-1", "name": "", "aln": "-MEDGVKEEPAKPKEVKSAEKAGWLKKSSGKFLSSYKDRYIQLDRTAIAVYENEELTTCLEKLELDNYETCHELKSAFKKK-HRLVLIRSPKSGNKVQDVKLQAPTPEEKEAWIKALCEGINKAKNKVFDEVKVDESSTLEHVTRDRPKGNRGRRPPTRIHMKEVANVSNDGMLRLDLDGEVTMLNGTHTLNKEGDKQTETSKPAVTLNNIQEEDAEEEPTPQKKVKPPMPPSKDNKPSESIKEDEPKNEEPAPQKNIVTPPMPPSKKSKPSISLESEADSTDYSESTPSNKGVQPPAPPSKHMKPNQQVTPATATVTTDQKETQEKNEEVDDDAGTKVNGALKEKEDQDKPEEVEILILSKQVMKPQVVMWDSPVVVSKDAEKEAKSAKKVSDITKEVTTTTEPQQLNPAPSSTPESVKKSPGPPAPPKKKPIKAPDKKEDTPHQGDQPVLSDSSNVSLNKVSEQSFKKDDPKLTIPDHKTEPVGDVSSEEMEEKSLDSGQHSGEESETGDQVTPSSTKLKGSSQGLDLETSEDDLEPSDSKAESLEDPSLETPSVTPETSVLSAHPTPNQCSNKSMSRTLPLSPSSKGRSASLGDLLSESTERMESKGKPQGSELKVLQSKVSIEIEKTGELLNAIATGQSEDKEEASPEMLLAAAMEKLRKADQFLKEARSFKDPKG------SKRLSL---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.:** **: .: .:****:***** :*. :****: * :: : *****: .*:*.:**..**.*::::: :*:* **::*:*** ****.*:*:**.: ****:***** ****:.***.*******::.:******:* :*.: ******:*:****..:.**: ***** * . * .* .: :* *. : . *** * .*: . .** .: . .* . :: ...:.:* *. : *.. :..* :* . * *:.* . . : *: : .. * *.:. ::. **:** * :**:. :..:. : ** . ...::* .:. : : . ..*:: : .. *... : *.:****** *... : ..* * :*.: ::* :*** : .:. ...* **: *:*:**:* *.*:* *.: : . .** .* ", "identical_positions": 163, "similar_positions": 173, "identity": "23.25%" }, { "cls_id": "homologset.agr.MGI:2143151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1PAI7-1", "uniprot_id": "A0A8M1PAI7_DANRE", "id": "A0A8M1PAI7-1", "name": "", "aln": "MFMPNTELHDNTQPVQLNPTNPIGPSKTPDLGGFRKIRSTGEPIPNPIPGLASDVLEMRVKEGSKIRNLLGFAMSRIE-GDGQTQVLFSGTGRAVTKTITCAEIMKRKVAGLHQVSKLQYRTVTEVWESQE-------------SQMTVHRTLPSICILLSKEPLDPHEPGYQPPVETNTLSEEHRQ----------------VDGVQGSG------------------KTEKRPLSPCDHPGLKRAALG------KD--------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P4G4-1", "uniprot_id": "A0A8M1P4G4_DANRE", "id": "A0A8M1P4G4-1", "name": "", "aln": "-----MELSGSAN-LQLNNS-----------AGFKRVCRLEDELCCPFPNLTAGVLEMRVKEGSKIRNLMGFSMARMQDGAALRQVVFSGSGRAVTKTITCAEIMKRKMPGLHQISKLQYRGLREVWESQDRG----------DAQVTVHRTLPSISILLSKDPLDPLEPGYQPPEDHQDLLEPGNQSLKQDLLEPGYQPLKDTKDLLEPGYQPLKSPKHLLDPRFQVIKDPKNLLEPGSQPPKNQDGLDPGYQLIKDPKNLLEPRYQPLKDTKDSLEPRFQLIKDPKNLLEPRYQPIKDTKDLMDSRYQLLKDPKDPLEARYQLIKDPKQRLEPGYQHPLKRSGEPSADCLLEPQVKRVCV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5PPN2-1", "uniprot_id": "RPP25_RAT", "id": "Q5PPN2-1", "name": "Ribonuclease P protein subunit p25", "aln": "--------MENFRKVRSEEAP----------AGDGDEG--GSPSSGPFADLAPGAVHMRVKEGSKIRNLLAFATASMA-QPATRAIVFSGCGRATTKTVTCAEILKRRLAGLHQVTRLRYRSVREVWQSLPPGPTPGQTPSDPAASLSVLKNVPSLAILLSKDALDPRQLGYQPPNLSPGPSSPPTVSTSKRSLG---------ESAAGEG-------------------TAKRSQPEPEAENEDRTA------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WE3-1", "uniprot_id": "RPP25_MOUSE", "id": "Q91WE3-1", "name": "Ribonuclease P protein subunit p25", "aln": "--------MENFRKVRSEEAP----------AGDGDEG--GSPNSGPFADLAPGAVHMRVKEGSKIRNLLAFATASMA-QPATRAIVFSGCGRATTKTVTCAEILKRRLAGLHQVTRLRYRSVREVWQSLPPGPTPGQTPSDPAASLSVLKNVPSLAILLSKDALDPRQLGYQPPNLSPGPSSPPTVSTSKRSLG---------ESAAEEG-------------------TAKRSQPEPEAENEDRTA------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUL9-1", "uniprot_id": "RPP25_HUMAN", "id": "Q9BUL9-1", "name": "Ribonuclease P protein subunit p25", "aln": "--------MENFRKVRSEEAP----------AGCGAEG--GGPGSGPFADLAPGAVHMRVKEGSKIRNLMAFATASMA-QPATRAIVFSGCGRATTKTVTCAEILKRRLAGLHQVTRLRYRSVREVWQSLPPGPTQGQTPGEPAASLSVLKNVPGLAILLSKDALDPRQPGYQPPNPHPGPSSPPAAPASKRSLG---------EPAAGEG-------------------SAKRSQPEPGVADEDQTA------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E9N4-1", "uniprot_id": "Q0E9N4_DROME", "id": "Q0E9N4-1", "name": "", "aln": "-----MMHYRKAENVEKELSK------------------SDLPFEDCMPKSQKDFLWMHVKGGTKVSNVIEFAQEALN-KGEHRCVVWSGSGGGVVKTISCAEVLKRSHP-LYQVTRMAYTSVEEHWKPQMEG----------LEEIIVTRQIPTLHILMSLDELPDTIDGLQKPNTSTDFWDGGGAQQQPHPRSQPRHQQQPHKPGAGRGG-----------------RPNKRTRPGRNKPGQQPEKPAAEENLPAS--------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. : : :. . : *:** *:*: *:: *: : :::** * ...**::***::** . *:*:::: * : * *:. .: * : :* : **:* : * * * * . . * *. . ", "identical_positions": 33, "similar_positions": 47, "identity": "9.12%" }, { "cls_id": "homologset.agr.MGI:2143163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H84-1", "uniprot_id": "MAPK3_RAT", "id": "Q66H84-1", "name": "MAP kinase-activated protein kinase 3", "aln": "MDGETAGEKGSLVPQPGALGAPALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSQNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKET-TQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPKPEWADVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMEVPQTPLHTARVLEEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQGGSSSASPGCNNQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMW7-1", "uniprot_id": "MAPK3_MOUSE", "id": "Q3UMW7-1", "name": "MAP kinase-activated protein kinase 3", "aln": "MDGETAGEKGSLVPPPGALGGSALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKET-TQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMVVPQTPLYTARVLQEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16644-1", "uniprot_id": "MAPK3_HUMAN", "id": "Q16644-1", "name": "MAP kinase-activated protein kinase 3", "aln": "MDGETAEEQGGPVPPPVAPGGPGLGG--APGGRREPKKYAVTDDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCILDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKET-TQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49071-1", "uniprot_id": "MAPK2_DROME", "id": "P49071-1", "name": "MAP kinase-activated protein kinase 2", "aln": "--------------------MLSLQN------QRQPKTTPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVLLDSERARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAEETWPEVQEEMTRSLATMRVDYDQMQIKALDKSNNPLLTKRRKKIEEMELYMANATRN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . :*:**. .:**** *: *** *:****::* ***: *: ***:* ** :**:*** **:.** :** *:***** .:.::***::**********.***::.* ********:**::* :*:::***::*****:********:.: :*.************ *. :**************************:*****:***::********* * *******.*** ***.**.*** :**: **:**: :*:.**::** * :.:.: ** * ****** *.*:*:* :: * :*:**** :**********::** *..*** **.***** . ....:", "identical_positions": 220, "similar_positions": 88, "identity": "57.14%" }, { "cls_id": "homologset.agr.MGI:2143169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XL6-1", "uniprot_id": "ACD11_MOUSE", "id": "Q80XL6-1", "name": "Acyl-CoA dehydrogenase family member 11", "aln": "METDVT--SDTVEVLPQHKFDLRSLEAYLNQHLPGFGSDSRAVLTVTQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKIQKALFSIGFPVAKPLLYCRDASVIGTEFYVMEHVQGRIFRDFSIPGVSSAERAAIYVSVAETLAWLHSLDIRSLKLDKYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMKNLPDSDSEECLVHGDFKLDNIVFHPKECRVIAVLDWELSTFGHPLTDLAHLSLFYYWPRTLPMINRGSHIPENTGIPLMEELISIYCHRRGIDPNLPNWNFFMALSFFKLAGISQGVYRRYLMGNNSSEDSFLTANTVQPLAETGLQLSKRTLRTTPPQADAKSQLFAQSRRGQEVLTRVKQFMKQHVFPAEKEVAEYYAQSGNSAEKWGHPLVIEKLKEMAKAEGLWNLFLPAVSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKKQWLEPLLRGDITSVFCMTEPNVSSSDATNIECTIQRDGGGYIVNGKKWWSSGAGNPKCKIAIVLGRTESPSASRHRQHSMILVPMDTPGVELIRPLSVFGYMDNMHGGHWEVHFNHVRVPASNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERILQIMCDRAVQREAFKKKLYEHEVVAHWIAKSRIAIEEIRLLTLKAAHSIDTLGSASARKEIAMIKVAAPKAVCKIADWAIQVHGGAGVSQDYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARRLTARM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B3DMA2-1", "uniprot_id": "ACD11_RAT", "id": "B3DMA2-1", "name": "Acyl-CoA dehydrogenase family member 11", "aln": "MEMDVT--RDTVEVLPQHKFDIRSLEAYLNQHLPGFGSDHRAVLTVTQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKVQKALFSVGFPVPKPLLYCSNASIIGTEFYVMEHVQGRIFRDFSIPGVSPAERAAIYVSLVETLAWLHSLDIHSLGLDRYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMRNLPDSDNEECLVHGDFKLDNIVFHPKECRVIAVLDWELSTFGHPLSDLAHLSLFYFWPRTLPMINRGSHIQENTGIPLMEELISIYCRRRGIDPNLPNWNFFMALSFFKLAGIAQGVYSRYLMGNNSSEDSFLTANTVQPLAETGLQLSRRTLSTVPPQADAKSRLFAQSRRGQEVLTRVKQFMKQHVFPAEKEVAEYYAQNGNSAEKWEHPLVIEKLKEMAKAEGLWNLFLPAVSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKQQWLEPLLRGDITSVFCMTEPNVSSSDATNMECSIQRDGGSYIVHGKKWWSSGAGNPKCKIAVVLGRTESPSVSRHKVHSMILVPMDTPGVELIRPLSVFGYMDNVHGGHWEVHFNHVRVPASNLILGEGRGFEISQGRLGPGRIHHCMRSVGLAERILQIMCDRAVQREAFGKKLYEHEVVAHWIAKSRIAIEEIRLLTLKAAHSIDTLGSAAARKEIAMIKVAAPKAVCKIADRAIQVHGGAGVSQDYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARQLKARM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q709F0-1", "uniprot_id": "ACD11_HUMAN", "id": "Q709F0-1", "name": "Acyl-CoA dehydrogenase family member 11", "aln": "MKPGATGESDLAEVLPQHKFDSKSLEAYLNQHLSGFGAEREATLTIAQYRAGKSNPTFYLQKGFQTYVLRKKPPGSLLPKAHQIDREFKVQKALFSIGFPVPKPILYCSDTSVIGTEFYVMEHVQGRIFRDLTIPGLSPAERSAIYVATVETLAQLHSLNIQSLQLEGYGIGAGYCKRQVSTWTKQYQAAAHQDIPAMQQLSEWLMKNLPDNDNEENLIHGDFRLDNIVFHPKECRVIAVLDWELSTIGHPLSDLAHFSLFYFWPRTVPMINQGSYS-ENSGIPSMEELISIYCRCRGINSILPNWNFFLALSYFKMAGIAQGVYSRYLLGNNSSEDSFLFANIVQPLAETGLQLSKRTFSTVLPQIDTTGQLFVQTRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEGLWNLFLPAVSGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTAKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ..* * .********* :**********.***:: .*.**::***:*:*****:**** *:****************:******:******:****.**:*** ::*:******************::***:*.***:****: .**** ****:*:** *: ** *.****************:***.****:*** ***:****.*.** *:****:***********************:****:****:****:****:****:**: **:*** *********: ***:. *******:***:**:***:**** ***:********** ** ************:**: *. ** *:..:**.*:*:***** :**:*****::******:*:*.*. **.:** :****:*******.***************:***************************************:**:*******:*:*** ******:*:******:**:**** ..*:::*****************:*****:..* ***: ********:****::********* **.****:*:***:*****:***************************:****** *****:**.** ** **** *********:******:***********:******.*:***********:**.**.* **** ***************** *.****************.***:***::*.*::", "identical_positions": 611, "similar_positions": 128, "identity": "78.23%" }, { "cls_id": "homologset.agr.MGI:2143205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PUQ3-1", "uniprot_id": "E9PUQ3_MOUSE", "id": "E9PUQ3-1", "name": "", "aln": "MSRVPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYQGTRRNTVPSSSSRMRSDGFDEESQRDYWRSKNEISGALEDDFLKTKSWNKKLYDYESNIPDRWGHSGYKELYPEEFETDSSDQQDITNGKKPSPQVKSSARESRKHKKSKKSHKKKQKKRSHKKQKKNKKEVTDITADSSSEFSEETRASSTRKRKQPHKSKKKSRKKSPKI-TFPLGGESGTSQSEDSASSSSEDIEERDTKKTKRKKKEKSVHVPMPDPEVQERTSKRRNWKVATDARSAESSEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1WC13-1", "uniprot_id": "B1WC13_RAT", "id": "B1WC13-1", "name": "", "aln": "MSRVPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYQGTRRNTVPSSSSRMRSDGFDEESQRDYWRSKNEISGALEDDFLKAKSWNKKLYDYESNIPDRWGHSGYKELYPEEFETDS-DQQDITNGRKTSPQVKSSAHESRKHKKSKKSHKKKQKKRSHKKQKKNKKEAPDITADSSSEPSEETRASSARKRKQPHKSKKKSRKKSPKK-SSPLGGESDTSQTDDSASSSSEEMEERDTKKTKRKKKEKNVHVPMPDPEVPERTSKRRNWKVATDAKSAESSEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZUT1-1", "uniprot_id": "NKAP1_HUMAN", "id": "Q6ZUT1-1", "name": "Uncharacterized protein NKAPD1", "aln": "MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDS-DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:****************************************:**:*: :****************** ***.******:*******:******:****:*:********************* ********:*.*******::**************************.***..********* **** **.:** ***** ******** * : * .**.**:::********: ************:**..*..:.: *: ***.** ******* :********", "identical_positions": 237, "similar_positions": 38, "identity": "80.89%" }, { "cls_id": "homologset.agr.MGI:2143217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64093-1", "uniprot_id": "S6A20_RAT", "id": "Q64093-1", "name": "Sodium- and chloride-dependent transporter XTRP3", "aln": "-MRLAIKRRASRGQRPGPDEKRAR-------------------------DMEKARPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYLIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNRTGYD-EECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTALMPYCVLIIYLVRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNDCQKHAVIVSVINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTASNLEEVKDYLASTYPNKYSEVFP-HIRNCSLESELNTAVQGTGLAFIVYAEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLRAMTGRPLNWYWKAMWAFVSPLLIIGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALG----------TFIRNRLKRGGSSPVA-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDB9-1", "uniprot_id": "S620A_MOUSE", "id": "Q8VDB9-1", "name": "Sodium- and chloride-dependent transporter XTRP3A", "aln": "--------------------------------------------------MEKARPQWGHPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNHTGYD-EECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTVSNLEEVKNYLASTYPNKYSEVFP-HIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLRAMTGRTLSWYWKVMWAFVSPLLIVGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALG----------TFIRNRLKRGGSAPVA-------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP91-1", "uniprot_id": "S6A20_HUMAN", "id": "Q9NP91-1", "name": "Sodium- and chloride-dependent transporter XTRP3", "aln": "--------------------------------------------------MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLNGNHTGYD-EECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFP-QIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALG----------TFVQRRLKRGDADPVA-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K7V4-1", "uniprot_id": "A0A0B4K7V4_DROME", "id": "A0A0B4K7V4-1", "name": "Transporter", "aln": "MAATKIIDAPRNGHEMAPLNTRARGDGTHGVTIVLTAPQRNSVQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLNG--TGFELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLG--------LNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKR-VKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIR-NPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFLMRSFQCLKVDLDIHQGSIRRNETTASTKEMIDNDDDDDEDDENDFSGPALGGHVKTQSDFSDDDEEDKPMTMRMMMMRPTTTTKTSNVLNVPTSRKNNYKKEAYDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. *. :**.:: *.*:*****:******** ***:**:*:::***:**:**: :**.:***** *::*.*.** *:*.*:*::* :*::*:::***** :* *:***:**: ***** ****. **:: *** *:*.* *****.**: :**::* **::* .*** *:* :*:: :::* :*:*******: :** ** *:::**:**:** ***:*:***:*:* :*..*::****:*:*:**.*******.*** *.*:* :..::**: *: *:*:**:* *:* *****.* :.*: . :*.:. * *::.:.* : : :*:: :: :*** **:.*.:********:::** :: : :*:**:* *** **:** :* .:* .* * .:*. : *: ::*:***. :*::* **:**:.:*:.:*.*:.*:::.*:* *** ::** .** .*: *** . **: * :.*:::: ::: : :: . * **:* * : *.** .:.: :: :..: :*:. * : : ::*. : . : ", "identical_positions": 249, "similar_positions": 206, "identity": "33.97%" }, { "cls_id": "homologset.agr.MGI:2143230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86UU1-1", "uniprot_id": "PHLB1_HUMAN", "id": "Q86UU1-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIG-SAARDISLQGPGLAPEHCYIENLRG-TLTLYPCGN-ACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP----QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPG-------AAGKKPAATSPLSPMANGG-RYLLSPPTSPGAMSVGSSYENTSPAFSPLSSP--ASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRP-----------SGARS-ESPRLSRKGGHERPPSPG--LRGLLTDSPAATVLAEARRATESPRLG-GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFS---------------DGLAT-RTLQPPESPRLGRRGLD--SMRELPPLSPSLSRRALSPLPTR--------TTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPT--LGESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSG--DLRVPVT--RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAG---ASGRSSEEPGVATQRLWESMERSDEENLKEECSSTES---------------TQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKE-------------------------------------------AEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK--------------------------------------------TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRS-KMDGEATSPLPRTRS-----GPLPSSSGSSSSSSQLSVATLGRS------------------------PSPKSALLTQN------------------------------------------GTGS--------------LPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP--SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PDH0-1", "uniprot_id": "PHLB1_MOUSE", "id": "Q6PDH0-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------MDPLNRSQLGPGCKTQAVVQKGPLDLIETGQGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIG-SAARDISLQGPGLAPEHCYIENLRG-TLTLYPCGN-ACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGVRAPGPTYNPGSAESESLVNGNHTA----QPATRAPSACASHSSLVSSIEKDLQEIMDSLVLEEPG-------AAGKKPAATSPLSPMANGG-RYLLSPPTSPGAMSVGSSYENTSPAFSPLSSP--ASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRP-----------SGSRSSDSPRLGRKGGHERPPSPG--LRGLLTDSPAATVLAEARRTTESPRLG-GQLPVVAISLSEYPSSGARSQPASIPGSPKFQSPVPAPRNKIGTLQDRPPSPFREPPGTERVLTSSPSRQLVGRTFS---------------DGLAATRTLQPPESPRLGRRGLD--SMRELPPLSPSLSRRALSPLPAR--------TAPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPT--LGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPRAQRKLSSG--DLRVPIP--RERKNSITEISDNEDELLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPETGELPSIGEATAALALAGRRPSRGLAGAIVVSGRCGEESGGASQRLWESMERSDEENLKEECSSTES---------------TQQEHEDAPGAKHQGEVLAVEEERAQVLGRVEQLKIRVKELEQQLQEAAREAEMERALLQGEREAERASLQKEQRAVDQLQEKLVALETGIQKDRDKE-------------------------------------------ADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVSKRKERLAVLDSQAGQIRAQAVQESERLAREKNAALQLLQKEKEKLNVLERRYHSLTGGRPFPK--------------------------------------------TTSTLKEMEKLLLPAVDLEQWYQELMSGLGTGLAAASPRSSPPPLPAKASRQLQVYRS-KMDSDAASPLPRTRS-----GPLPSSSGSSSSSSQLSVATLGRS------------------------PSPKSALLAQN------------------------------------------GTSS--------------LPRNLAATLQDIETKRQLALQQK---------------GHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAGPFSAGP--SGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63312-1", "uniprot_id": "PHLB1_RAT", "id": "Q63312-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTLGARGRRTRSPSPT--LGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSG--DLRVPIP--RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPETGELPSIGEATAALALAGRRPSRGLAGAIVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTES---------------TQQEHEDAPSTKLQGEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAMDQLQEKLVALETGIQKERDKE-------------------------------------------ADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVSKRKERLAVLDSQAGQIRAQAVQESERLAREKNAVLQLLQKEKEKLTVLERRYHSLTGGRPFPK--------------------------------------------TTSTLK-----------------------------------------------EVYRS-KMNGDMASPLPRTRS-----GPLPSSSGSSSSSSQLSVATLGRS------------------------PSPKSALLAQN------------------------------------------GTSS--------------LPRNLAATLQDIETKRQLALQQKVELPPAEPLSPEDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAAFPAGP--SGFPTLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7TEA5-1", "uniprot_id": "A0A8N7TEA5_DANRE", "id": "A0A8N7TEA5-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "-----------------MDLNECEEMIDNSVDMDRMNRNVPEQGRQTHQVLQSTPLDLIETGKTLKVQAERPHLVSLGSGRLSTAITLLPLPEGKTTLG-HGNTDINIQGPGVMSQHCYIENVGA-VITLYPCGN-QCSMDGLAVTKPVRLAQGCMLCFGQSSFFRFNHPEEALRMKSLMPGGSPGFTNTYKN-HSETHGQLNGN--------HLPLHERSRPGAGTLVRSIEKDFQDIMNSLSMDDGQ---AEHCKKARHPIPQS---AMLNGSSRSLVSTPTSPGALSVSSSYENTSPPYSPLSTPSMVSS-------PGACLDS------ANTRSNSYTHTVQAPVPQPRNFTSKNCSSNGGLKDQESARIQ-KALTETPSSPGANRRGDNTHGSTSGS-------------------------SLVPGDLGRQVNTRFTSSSSASS--SPRSSIGSSVQE----------------SSSSIQSLS--------------------------RALLPPDSPQSSRRSVETSSIRELPPLSPSTSRRGILGVPVLPVALP---SVSLSSRGRTVPDSPRLQRRT-------TAEEEVGNTRLHTRSPSPVSTLLKDQSGSKQKGG--LSSAVG--SQTGVSPLTSPRNQRKAS---REARQVPPRTRERKNSISEVSDKEEDLLEYHRWQREERMREQEMERLERQRLETILNLCAEYNKSD-PPVGVDAGRVCLFPGMEEVSVRRPGP-------------DPVSVPGQ-SSHRQRESEEDNLKEECSSTES----------------QHQEHEDTSVLGQQERVYLEEERLRILARVDELKTRVTDLEQQIQESRQEAEMERALLQGERRAELDQVEAELEIINQLQLKLNEVENATQREKEKERAKVSAERDVLARLKDSYSELKGQLHKCPESLREHLQEQLTRKVEALESATKRFEDLEFRQLERESGIEEEKETVGRQLLQEKAEYHRNVAKRKEKMAALEIQANQLGLQAAQDCERMAKDRTLALQMLHKEKERLSSLEKRYQSLTGGKNFSKPTSTKEEVLYISEPDFLDELPTQNSLLPSSSTQRSTPQICSNRPQEEYLKLSDVYKMYGNGCVPAQTASPNS--LCLPLAVTSDTPREEYVTVSQLNQLFGMPKVDPYPTSSVQSFQAIDPAHSSHTSQCGSSQSLLVETQPAWSRPSIPRLDSERWYQEIMAAGQPSHSCPPPLPAKCLSS-----RKPMQMCKQ--DGETNGTLS-----------------GRNTPTKS----------LP-DLSPAYLDIDSKRQLDLQSR---------------GLYTCDDSRIRPMDHKLS-------HWGAPP------------SGAPMVHHSILHHQAP-----PAGESTYDTLSLESSDSVETSVSTGNNSACSPE---SSNGLAGLRLEEMEKMLKEAQQEKARLVESREREVQARKQMLEAERRRREEVERRLLDETAHRQRLVEEEVKMREKQCSQARPMTRYLPIRKEEFDLRSHVESSGHSVDTCAYVIVTEKMCKGHLVKMGGKIKSWKKRWFVFDRLKRTFSYYVDKHETKLKGVIYFQAIEEVYYDHLRSATK-----------SPNPSLTFCVKTHDRLYFMVAPSPEAMRIWMDVIVTGAEGYTQFMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HCC6-1", "uniprot_id": "A0AC58HCC6_DANRE", "id": "A0AC58HCC6-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "MRSHVEGLVSLAARKLLQDSHVPEQVSDSTLAMDTLNQNLS-HGHQSHQVLQSTPLDLIETGKALKVQAERPHLVSLGSGRLSTAITLLPLPEGKTTVG-HGAMDISIQGPGVAAQHCFIENRAG-IITLHPCGN-QCSMDGLPVNKPVRLSQGCMLCFGQSAFFRFNHPEEAFRMKSMMPEGGQTASVKNWT-HKDSENLVNGNHSSGEAKSHLVSNERVRPEHSAIVSSIEKDLQDIMDSLVMDDPQPSSSESKKPSSQSISQSPLSPMLNGGGRFLLSPPTSPGAMSVGSSYENNSPPFSPLSSPSAASSGSYTTLSPIGCQDQPHMLPPVPVRSSSYNYTSQPPIPQPRTILPSYSSGSSGPKVPESPRLQRKALLEAPPSPKPSRRGLNQDSSVAKTPDSPIQTHILPSVSISTAPTDVPSVSRVPVPGSPRLATKFSTASSPASPSSPRTKTTIVLQDRPSSPFREQPQPDRSLTSSPSHQLSPPSRSFQPPLDPIVHIIQGGPSHPHPRTLQPPESPRLARRNLEGSSMRELPPLSPSIARR---GVPVLPGALPGTLRTPESPSPRMVPESPRLRRKTGS-----PTEEPFSPRAMRTRSPSPTSGLTGESSGRKGSFGNSLSSAFSLSSLPGSSPRSSPRSHRKMSAGHRDLRMPHPGMRERKNSITEISDNEDDLLEYHRRQREERLREQEMERLERQRLETILNLCAEYNKGDGPPGDLGRMGVSGLGSRDGLNVRRPSM-------------DSVNSASLRATQRQRESQEDNLKEDSSSTESAQLDGRTPALLNGQNGQAEESLGSGSIGRLELGYLEEERVRVLAKVDELKARITELEQQLQESKQEAEMERALLQGERQAEMEQIETETEIINQLQRKLTELESSIQREKDKERANVDAEREALERLQDGYNELTSQLHNCPESLREQLQEQLKREAETLEAATKQFEDLEFQQLERESSLEEERETISQQLMQDRAQYHSSVAKRKEKVVALESQASQLGIQAAQECERLAKDRTITLQMLHKEKERLASLERRYQSLTGGKTFPK---------------------------------------SSNTIKEEYLKLSDVYKMYGSECHDIQLASASSHGLSLALDPAETAPREEYVTVGQLNQMYGMPKVESSPTSPVQSVQPSLADFPRLPSPHGSSLSLSFERQSDWGRPQMPVLDLEHWYQEVMAAGDVNQLCPPPLPAKAFSSSSSSPRRPVQVYRSRLDSDCSQSLLRPKVSAGLSPTYTTATLGRNTPSRSPLMVANSTGSLPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAELKQKAAVEAQCQWEALHGSQTQLHQPFSSSPAPALHHSILHHTAP-----PCGEQPYDTLSLESSDSMDTSISTGNNSACSPDNMSSASGMDALKIEEMEKMLKEAQLEKARLIESRERETQSRKLMLEEERRRREEAEKRLQEETLHRQQLIEKEVKMRARNFSQARPMTRYLPIRKEEFDLRSHIESSGHSVDTCYHVILTEKMCKGFLVKMGGKIKSWKKRWFVFDRLKRTFSYYADKHESKLKGVIYFQAIEEVYYDHLRSATKKGFFNLNL-TNSPTPTLTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX80-1", "uniprot_id": "Q9VX80_DROME", "id": "Q9VX80-1", "name": "PH domain-containing protein", "aln": "-------------------------------------------------------MSLTKKDPSLRVAASDPHLVSLGGGRLSTAVTIHYIHIGDTTIGSAASCSISLNGSGVRPLHCTIYRSDANEVTLVPEKDSRLLIDGAPILEETKLSQGAMITIGNSNYLRFNNPDEAQMMRSAMGSNERISMP------------------------QIDFTQSARQAHELSQSLELESFYESIINPINNPST-------YELECPKVFSSDLVTVNMPAKDVLGQKYASFARNLAENHRNEKQLNNQYAKGVGSNGGYWNVPSNAAIYKEQHQQQHQQAPQDLLTKVNND-------------------RYDRYPKAGGLQIYSMNGVNSDINNGPATGNNSGTG-------------------------GGAELEDMLKICTEYADRNNSMPSTHNVSSTSS-------------------ITSSPIVQNRIKTNG----------------------SLPRDKNKSPFPQQAGVASSANISLLSSSSGYENVRLLGPNRVEINGQIHVPASAGDGGSSSGVSSNALAP------TAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPPLASSAVVSTSKPIPIP------------SMVKPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRSNKNINNLTLNLQSVESQTQSPKPS-RKPAP-------------APRSIHLEQRQRRELIQRRKQLKRELAELPP-----------------------SAGIEGLELKLGEQP----LAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAKLKQSIEIKQDQLKKLRAMLKQKPNNACLKEELQ-----------------------------------------LVCESLESDRKTFEDLEFQYFEEESEHHASHEEFKR--QEQRLMLEAELAALRIQIGPDEEEPGSPTSPGSTGSNLVN---GVMSQSLFGSAELLCPKRRNQEDLMSKSVNEN----------------------------------------MFYNHKIEANTSTPKRLPLQLFEDLAGGSCEQISFNLSLQGDRFEVNPLERRVPSQDDIDRSCKVANDAPISASQGASTKIFDSIMEIERNRKLLLAQQGHQVIEHE------------------------RQKMYDLKKKS------------------------------------------HDEAR--------------TQYLLSTQQSMEQQRQLESDAN--------------GGKDAKLFEKTELQKLNQKPGEPVDDQVQKIAGDKENNVQNRKSTGSSPTTTTTTTTGGG----TTPQQQRHSQPELEHHAIALGIGGGGSGGAGGANQMVARSPRPLSEANNCDATIEAPKFANG--MDSSASPAVADNKRASSNSQDTASAGSGSGNSGSGGSTASDRKRVLP----KHQRPLTRYLPIFSPDLNLRHHIETAGHQIDPCPHVFVDAHSCRGYLHKLGATFHAWSRRWFVLDRQRSALIYYSDKSERKPRGGAYFATIDEVYLDHLNASKS------------GRPHCTFIVKTKKRSYNLQAASDSAARIWIDAIITGAQGNLDY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .:.. : . :*. . . : ** . : . . * : * .::* ** :: :**:: : : *: .. : : *:*. . . . ..:**.: :. . .. * *: *. . : :: *:::: . : : *.: :.:: :: : :.:*: * . ..: : ::**: * ******: :*.** . .:* : ..: .:: : :: : :... . .: : * * . * * .:. ..* . : : :: *: . . . . . : .. : . * .: .:: :*** : . * . .: . . : . : .. : : :. .** . *...* ..: : . . :: : :: .: : ::* . . : : .. .. . :.: : .: **:***** . :::*: *:*::** :*.* :*.: : *:*.* *:*..:::*.:****:** : :: ** ** * * :* ** :*:*** ***.:: . * ** ***:.* * : *.* .* ***:*.*:***:* :: ", "identical_positions": 114, "similar_positions": 235, "identity": "6.78%" }, { "cls_id": "homologset.agr.MGI:2143261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG90-1", "uniprot_id": "D3ZG90_RAT", "id": "D3ZG90-1", "name": "", "aln": "-------MLKELHLSLSLVLVFACGLLYQLTLR---------------------------------SQCFFACLPPFTSP--------------QGLEGLLRNGRSIVFIETSERLEPP---------PLVSCAVESAAKIYQEQPILFFMKGLSNATQMTSNTSSYPAFSLLSAINNVFFVPLDMKTLFEDTPLFSWYTKVNSSREKHWLHVSSDASRLAIIWKYGGVYMDTDVISIRPIPEE--NFLAAQGSQHSSNGVFGFLP---HHPFLWACMENFVEHYNSGIWGNQGPKLMTRMLKIWCRLKDFQGLGD--LKCLNISFLHPQRFYPIPYPEWRRYYQVWDRDLSFN---DSYALHLWNFMNREGKTVVRGSNSLVENLYQKHCPKTYRVLIQGAEGTVSRKSGKGNR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14BT6-1", "uniprot_id": "A4GCT_MOUSE", "id": "Q14BT6-1", "name": "Alpha-1,4-N-acetylglucosaminyltransferase", "aln": "-------MLKEIYLSLSLVLVFACGLLYQLTMR---------------------------------SQCFFACLPPFSFP--------------QGLDGLLRSGRSIMFIETSERVEPP---------PMVSCAVESAAKIYPEQPIIFFMKGLRDSVQLTSNTS-YPAFSLLSAINNVFFVPLDMERLFKDTPLFSWYTKVNSSTEKHWLHVSSDAARLAIIWKYGGIYMDTDVISLQPIPEE--NFLAAQGSRHSSNGVFGFLP---HHPFLWACMENFVEHYDSTIWGNQGPQLMTRMLRVWCRLKDFHGLGD--LKCLNISFLHPQRFYPIPYPQWKRYYQVWDKEPSFN---ESYALHLWNYMNKEGKTVVRGSKTLVENLYQKHCPKTYRVLIQGAEGTVSKKPGTGSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNA3-1", "uniprot_id": "A4GCT_HUMAN", "id": "Q9UNA3-1", "name": "Alpha-1,4-N-acetylglucosaminyltransferase", "aln": "-------MRKELQLSLSVTLLLVCGFLYQFTLK---------------------------------SSCLF-CLPSFKSH--------------QGLEALLSHRRGIVFLETSERMEPP---------HLVSCSVESAAKIYPEWPVVFFMKGLTDSTPMPSNST-YPAFSFLSAIDNVFLFPLDMKRLLEDTPLFSWYNQINASAERNWLHISSDASRLAIIWKYGGIYMDTDVISIRPIPEE--NFLAAQASRYSSNGIFGFLP---HHPFLWECMENFVEHYNSAIWGNQGPELMTRMLRVWCKLEDFQEVSD--LRCLNISFLHPQRFYPISYREWRRYYEVWDTEPSFN---VSYALHLWNHMNQEGRAVIRGSNTLVENLYRKHCPRTYRDLIKGPEGSVTGELGPGNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQK4-1", "uniprot_id": "A4GT1_DROME", "id": "Q9VQK4-1", "name": "Alpha1,4-N-acetylgalactosaminyltransferase 1", "aln": "-MLLWLPIAVARRMFIILVLMVIGGLFYIYTS---------------------ENKYHS----CFMEGQVLATQQALTADGETN-----LLGDVLQADPKPSPGNSIFFHETSCRLSENRQLETLKVTARQACAIESAAMHNPNFQVFVLFAGPTYRISNNKSHP-QPLLEAILSYSNVHLRRLNLESYASGTPMEEWLKDGRLSRSKYLFSHISDFLRYLTLYRYGGLYLDMDVVVLRNMEKVPPNYTGAESNTHLAAGVMNLAATGFGHEIAASCLRDFQHNFNGGDWGNNGPGVITRVAQKICGTKDIALMREDPKRCMGFKVFGRGAFYAVPWKQWRDFFEPENLEETIARCKDSYVVHVWNKHS-SKLPIKIGSKNAYALYAEQNCPRSYKAAGEYF-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBL5-1", "uniprot_id": "A4GT2_DROME", "id": "Q9VBL5-1", "name": "Alpha1,4-N-acetylgalactosaminyltransferase 2", "aln": "MKVSRTLIVVGSLLLILSIVLTYKWIAYNHAYPKAQTELTNSTKKANLIDSKAKNKKHVQNSLAKKAAKSVANQSKFKLDKVSKKIPVIPLLDVLKAKKQPSRGQNIFFHETTN-FKRIEKSSVVQLTAREACAIESAALHNPGLTVFVLFAGATHRPSSG-----DPLIRALHNYKNIRLRHLNLWRYAAGTPIAKWLKSGKLFKSKFLFPHVSDLLRYVSLYKYGGLYLDLDVVVQQNLEKLPPNFTGAESNISVACGVMKMSPGGLGHKIATMCLRDLEANYNANKWGTNGPGVITRVVKKQCNTDNIKSVINNPKRCNGFKVFDANAFYAISWLQWKDFFQPNRHNVTMKRVSKSPVIHVWNKFS-KGWKVKTKSNCAYTTLAKIHCPRSFAAAGELF-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: : * : . :. . ..*.* **: .. :*::**** :..:: * * : : .*: : *:: .**: .* .. . .: : ** * :::***:*:* **: : : : *: .*:.. : *:: : . * : *:.:: :::. **.:** ::**: : * .:: : : :* .:..: **.:.: :*: ::: : :: * .:*:** . . : *: . :**::: : ", "identical_positions": 50, "similar_positions": 111, "identity": "12.05%" }, { "cls_id": "homologset.agr.MGI:2143266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EW48-1", "uniprot_id": "F7EW48_RAT", "id": "F7EW48-1", "name": "", "aln": "MEMSQDPRLSFLWNSDRPLPLMQYLGLGKKEGAVKSAHFEHLGQLSFSERVKLHCNSDLSTSICFLKQDGQHGQKASFWKKTVFQGKLSLPEFLTKQASTMVFQGVWTSPIMWFFYSMTSGFLTDGATILPAPQNFSVRSTNMKHLLMWNPVTQPGETVFYFVQYQGEYESLYMSHIWIPSSQCSPTKGLECDVTDDVTATVPYNFRVMAMLGSQSSAWSNLEHPFNRNATVLTPPRMEVTEHGLHLVVELEDLGPQFEFLVVYWRMEPGAVVRLPTHPARPLSQALEKAHGFPGERVKVVRSGDIPVHLETMDPGVMYCVKAQALVKTIGRHSAFSQPTCVEMQGESLPLALALFAFVGFVLILVVALLSVWKMGQLLRYSCCPAVVLPDTLKVTSSSQKLIRCRKEEVDACAVTVLSSEHLFGVWISQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9A6-1", "uniprot_id": "E9Q9A6_MOUSE", "id": "E9Q9A6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------MISQGVWTSPFMWFFYSMTSGFLTDAVSVLPAPQNLSVQSTNMKHLLMWNPVTQPGETVLYCVEYQGEYESLYMSHIWIPSSQCSPTKSLECDVTDDITATVPYNFRVKAMLGSQTSAWSNLEHPFNRNATVLTPPRMEVTEHGLHLVIELEDLGPQFEFLVVYWRREPGAA-----------------------EHVKMVRSGDIPVHLETMEPGAMYCVKAQALVKAIGRHSAFSQPTCVEMQGESLPLALALFAFVGFMLILVVVLLSVWKMGQLLRYSCCPAVVLPDTLKITSSSQKLISCRKEEVDACAVAVLSSEHLFGVWISQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXL0-1", "uniprot_id": "I20RB_HUMAN", "id": "Q6UXL0-1", "name": "Interleukin-20 receptor subunit beta", "aln": "-----------------------------------------------------------------------------------------------MQTFTMVLEEIWTSLFMWFFYALIPCLLTDEVAILPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAWSILKHPFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLVAYWRREPGAE-----------------------EHVKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGEAIPLVLALFAFVGFMLILVVVPLFVWKMGRLLQYSCCPVVVLPDTLKITNSPQKLISCRREEVDACATAVMSPEELLRAWIS--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : :*** :*****:: . :*** .::******:** **********.** ***** * *:********* ******** ** *:. *******:*******:** * ****:**** *:******:*:** * **:*:.*:***:*************.*** **** *:**:****.********:**. ******::**:***:*****. ***:***::**.*********:*****. * *****:**:*****.********:*.*.**** **:*******.:*:*.*.*: .*** ", "identical_positions": 220, "similar_positions": 58, "identity": "51.04%" }, { "cls_id": "homologset.agr.MGI:2143267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58196-1", "uniprot_id": "PLS4_MOUSE", "id": "P58196-1", "name": "Phospholipid scramblase 4", "aln": "MSGLVPTAPEQPTEEMENQIKSPTAVPDAPPDYNSHFAPGPAGPVASP----SAGLPMGYYIPQQPGAIPLYHPTGGTHPIQYQPGKYPVTNQPAPIMWMAGPAPVPNCPPGLEYLAQ---------------------------------LDNIHVLQHVEPLELMTRFETNNRYDIKNNIDQMVYIVTE----DTDDFTRNAYRNLRPFVLRVTDCLGREIMTMQRPFRCTCCCFCCPCARQELEVQCP---------PGVTIGFVAEHWNLCRASYSIQNE--KKESMMRVRGPCATYGCGSDSVFEINSLDGVSNIGSIIRKWN-GFLSTM-------------VNADHFEIRFPLALDVKMKAMIFGSCFLIDFMYFERPPPRRMSR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2G4-1", "uniprot_id": "A0ABK0M2G4_RAT", "id": "A0ABK0M2G4-1", "name": "Phospholipid scramblase", "aln": "MSGVVPTAPEQPTEEAENQVKATTAVPDAPPDYNSHFVPGPAGPAAPP----SAGLPMGYYVPQQPGAIPLYHPTGGTHPIQYQPGKYPLTSQPAPIMWMPGPAPMPNCPPGLEYLAQAFRSDYNESHLESPISVPNEISKDFETQNLLEKLDNIHVLQHLEPLELMTRFETNNRYDIKNNVDQMVYIVTE----DTDDFTRNAYRNLRPFVLRVTDCLGREIMTMQRPFRCTCCCFCCPCARQELEVQCP---------PGVTIGFVAEHWNLCRASYSIQNE--KKESAMRVRGPCATYGCGSDSVFEVNSLDGASNIGSIIRKWN-GFLSTM-------------GNADHFEIRFPLALDVKMKAMIFGCCFLIDFMYFERPPPRRSSR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRQ2-1", "uniprot_id": "PLS4_HUMAN", "id": "Q9NRQ2-1", "name": "Phospholipid scramblase 4", "aln": "MSGVVPTAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPPPTGYPGGLPMGYYSPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGPTPMANCPPGLEYLVQ---------------------------------LDNIHVLQHFEPLEMMTCFETNNRYDIKNNSDQMVYIVTE----DTDDFTRNAYRTLRPFVLRVTDCMGREIMTMQRPFRCTCCCFCCPSARQELEVQCP---------PGVTIGFVAEHWNLCRAVYSIQNE--KKENVMRVRGPCSTYGCGSDSVFEVKSLDGISNIGSIIRKWN-GLLSAM-------------ADADHFDIHFPLDLDVKMKAMIFGACFLIDFMYFERSPPQR-SR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z868-1", "uniprot_id": "A0A8M6Z868_DANRE", "id": "A0A8M6Z868-1", "name": "Phospholipid scramblase", "aln": "----------------------------------------------------------------------------------MLPETCLSPLEVTAMLSSPNPYHYPSQLEGLTRIER-----------------------------------LFVFRDHPECIEVCCEVQPNRSYSVKDDSGNKVFSVTE----ADDCCG--SQYAERFFVMNVTDNLNREVIRLVHPS------VCTRCSSHELEVQSP---------PGTPIGYVRQNWHILLPKFTVENE--RGEPEFKIMGPSVFWTCCTDVNFELVPLNAAAVERSFGRIINPSYWAGP-------------NPGANFVLEFPSSLQVKMKATVLGACILIHNMYYENKQ---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEL2-1", "uniprot_id": "A0A0B4KEL2_DROME", "id": "A0A0B4KEL2-1", "name": "Phospholipid scramblase", "aln": "---MLQNNAVRTLQYDSEIRVAQQPSLSEPRVYDSHIS--------------------------------ITSQPRPEAPRIPLPVPIATVTGSRTLIPLSGYDCLADLPS--VHIEQ-----------------------------------TFELNDVRLPFAALTGVSSENRYVVRSPLGDAIFAANE----SSTEKNRLLWGAGRPFQMHLLDKTHQEALVFRKKLAMG----SMCCQAKSLEIWIP---------PGNLLGKVVQSPTFMQPEFFIEDES-TGQLTFCVEGPVGLGFCCFS--LPKDCYFKIHSGGNMRASIDHKWLASK-------------SQYTTNIYFSDAKLTAKERALILGSAFLLEYLFFQTRF---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47140-1", "uniprot_id": "AIM25_YEAST", "id": "P47140-1", "name": "Altered inheritance rate of mitochondria protein 25", "aln": "---MHRTAIFLTYRSCMRNFSTLSKTLTVSSGK--------------------------------------VIRNGPFRRVIREKNQITKAPSVKAFKENSNSGIIKVHDPIATTILN---------------------------------EPTVIIERQIEFMNVFLGFEQANRYAIMDVNGNKIASMMERDFSITKAIMRQFYRLHRPFLVDVFDNWGNVIMTIKRPFSFINSHIKTIIPPSAYVDNGSDSTHYHDGKEGTTVGETIQNWHLWRRRYELFQKDGVEGSTFDQFGKIDAPFLSFDFPVTDADGKIMASVDRNWVGLGREMFTDTGVYVVRFDSQRCFDNIYPTEMLSSQVLTLDQRAVLLANAVSIDFDYFSRHSRQTGGFLSFGGGYDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .. : . . . : .. . * : . .: : * * * : : * . : : : . * :* . : : : : :: : * . . . : * . :* ::. .. :. ::. ", "identical_positions": 10, "similar_positions": 49, "identity": "2.49%" }, { "cls_id": "homologset.agr.MGI:2143272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2P0-1", "uniprot_id": "DI3L1_RAT", "id": "Q5U2P0-1", "name": "DIS3-like exonuclease 1", "aln": "MLQKREKVLLLRTFQGRTLRIVREHYLRPSVPCNSPLCPQPATCRNDGKLLSAEVTHYVIPDWKVVQDYLEVLEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCVLFANEFQQHCYLPREKGEAMEKWQTRSIYNSAVWYYHHCEDRMPIVMVTEDEEAIQQYGSETEGVFVISFKNYLDNFWPDLKAAHELCDSIIQSRRERESESQETHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSGLVSDILIHGSKARNRSIHGDVVVVELLPKSEWKGRTAALCENDSEDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAEALQDFRVVVRIDSWETTSVYPNGHFVRVLGRIGDLEGEIATILVENSINVVPFSEAQMCEMPVNTAENPWKVSPKEEQERRDLRSTHLVFSIDPKGCEDVDDALSVRTLNNGN-LELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPEFKTLEEQNRQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPSDPLVNKLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKVEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDPETEERCVVDGIIYSIRTNGVLVFIPRFGIKGAAYLKNKDGLVISCGPEGSSEWKPGSLQRSQNKIISTTAGGQSVTFHLFDHVTVRISVQPSRCHSDMIRLEIVSNKPYMMPNTELCHQSSLLLKSELVKEVTRSVEEAQLAQEVKG---KVIEEEHQEYRQTKGRSLYTLLEEIRDLALLDVSDSYAM-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0S1-1", "uniprot_id": "DI3L1_MOUSE", "id": "Q8C0S1-1", "name": "DIS3-like exonuclease 1", "aln": "MLQKREKVLLLRTFQGRTLRIVREHYLRPSVPCNSPLCPQPAACRNDGKLLAAEVTHYVIPDWKVVQDYLEVLEFPELKGVIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCVLFANEFQQHCYLPREKGEAMEKWQTRSIYNSAVWYYHHCEDRMPIVMVTEDEEAIQKYGSETEGVFVISFKNYLDNFWPDLKAAHDLCDSILQSRRERETESQETHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLHGASSKDSGLVSDILIHGSKARNRSIHGDVVVVEMLPKSEWKGRTAALGENDSDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAEALQDFRVVVRIDSWEATSVYPNGHFVRVLGRIGDLEGEIATILVENSISVVPFSEAQMCEMPVNTPENPWKVSPKEEQERKDLRTTHLVFSIDPKGCEDVDDTLSVRTLNNGN-LELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDKQSQQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPKDPLVNKLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETEERCIADGVIYSIRTNGVLVFIPRFGIKGAAYLKNKDSLVISCGPEGSSEWKPGSLQRSQNKIISTTAGGQSVTFHLFDHVTVRISVQASRCHSDTIRLEIVSNKPYMIPNTELCHQSS-LLKSELVKEVTRSVEEAQLAQEVKG---KVIQEEHQEYCQTKGRSLYTLLEEIRDLALLDVSDSCAM-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF46-1", "uniprot_id": "DI3L1_HUMAN", "id": "Q8TF46-1", "name": "DIS3-like exonuclease 1", "aln": "MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGN-LELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKV---NIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2RV18-1", "uniprot_id": "DI3L1_DANRE", "id": "A2RV18-1", "name": "DIS3-like exonuclease 1", "aln": "-MIKTEKILHLNSSKGRKVRVVREHYMREQVPCGSSLC--QADCQNVGKVLSRDVTHYVVPDVGVVRDFLEILELRELQGIVLTQTAYQTVQHTRGRRHYNRLRSLLKDPRHDCVLFANEFQQYSYCPREKGESQDKWHTRNVYNAAVWYYNHLAGLQPVVMITEDRDAISEFSASNSGVFVISTQEYLLGFWPDLQAAHDLYHSIAQTLQERENDGAE---KVYTEHLPAEVLEAGIKSGRYIQGILSVNKHRAQHEAFVRYEGSASKNTELNSDVLINGAKHRNRAVHGDVVVIELLPRNEWKGRTMALTEGQGEERPLEDTQSQPMPTGRVVEILQRNWRDYVVTLPPFEEMQSQSRNSQKILVVPWDYRIPKIRISTQQAEALQDQRVIVRLDSWESTSVYPNGHFVRVLGKSGELETEIQTILVENCIHVPPFSEAQLREMPVNTEENPWQMDSNEVSSRRDLRDSHLVFSIDPKGCEDVDDTLSVRTLPGGKRLELGVHIADVTHFVREGSLTDLEARSRATTYYLADRRYDMLPAVLSADLCSLLGGVDRYAMSVLWELDAETLEVCSVWFGRTLIRSSYQLHYELAQSLLNG---EEVEVPELNPLKGSQRDQKMSELLQALETLTRVARHLRAQRDKGGALELEGVEVRAQLDEEKNITALVPKQPLEVHETVAECMIYANHWVARKIQESFPHHALLRHHPPPKQEFFNHLIDSAKAHGFSIDTRSNRALADSLERAVDPRDPLVNRLLRMMATQAMSNALYFSTGSCPEEQYYHYGLALARYTHFTSPIRRYADVIVHRLLMAAVQLEKDESPSKALACNKELEELAQHINNKNRAAQHSQKQSIELFQCMYFRDKDSHTDERCVADAVIYAVRANGFLAFVPQYGLKGAVYLKDREGQVISVDGDGKCEWKPGTLQKYSDKIITSTSTG-THTFYLFNHVTVRISVEPSRCHADSLNLELISNKPHCAVQPE--SQPAGGGRSGLVEEVVRWAEEASLQAEEQRGRKPKLSKEEKQFRQSKTPNLYVLLQEISELALMDLSICQITNSEEQTCTVSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * **:* *.: :**.:*:*****:* *** *.** * * : **:*: :*****:** **:*:**:**: **:*::: *** *:*** ****:**:**.****.****:******** .* ***:**: :**:**.:**:*****:* . *:**:***.:**.::.:...*****: ::** .*****:***:* .** *: :***.:. * * *.**** *****************.******* ***** .*::**:: * **:**:* * ***::******:*:**:.****** ** *.: :::. :: *:******** ***:********:*. **:***.:*:*****.*****************:*** **:**:****:**************: *:** ** ******.* * ******: ****** *.**::..:* ..*:*** :****************:****** .*: ************** .* *:***:****************::****************:*::**** : *: .**:***:***:*:*.** **.**:* ::**:: *. ..:: *:.**: *: .** :***:**:** ********** .***::*** *:**************** ******:** *****:****:****:****..* :.***:** ******::*****: * ** **:**:*** *****************.**:::****** :***********:*::********:. :*. . . * .**:****.:****:*:***:***** ********:*:*. *:***: *.:**::*:**.* *:*::*:***.***:::. *** . :. .*****:**: .:** ::*: * : **:**:*******::.****:* :.**::****: :.* *.: :* **:**.: .***.* * : :.:* ::: *:* .**.**:** :***:*:* ", "identical_positions": 651, "similar_positions": 257, "identity": "60.9%" }, { "cls_id": "homologset.agr.MGI:2143311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHB5-1", "uniprot_id": "A0A8I6AHB5_RAT", "id": "A0A8I6AHB5-1", "name": "BBSome complex member BBS4", "aln": "MSLERYSFRRCTLACSDSVDLFHLLGSTEMPMKTQVPASIESQKPRPKKAPEFPIVEKLNWLIHLYYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLN-QKDWEICHNLGVCYTYLKQFS-----------KAQDQLHSALQLNKHDLTYIMLGKIHLLQGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGVYQKAFEHLGNALTYD-PANYKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYVEAVRLDKC------NPLVNLNYAVLLYNQGEKKGALAQYQEMEKKVHFLKDNNP-LEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHRTNSGSKSATLQQPLGSFQALGQAMSSAAAHRK--IPSGAVG-AQLTKPPSLPLEPEPEPTVEASPTEASEQN-KEK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1Z7-1", "uniprot_id": "BBS4_MOUSE", "id": "Q8C1Z7-1", "name": "BBSome complex member BBS4", "aln": "------------------------MAEVKLGMKTQVPASVESQKPRSKKAPDFPIVEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLN-QKDWEICHNLGVCYTYLKQFN-----------KAQDQLHSALQLNKHDLTYIMLGKIHLLQGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGVYQKAFEHLGNALTYD-PANYKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENARRAYVEAVRLDKC------NPLVNLNYAVLLYNQGEKKSALAQYQEMEKKVNFLKDNSP-LEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKTKHRTNSGSKSATLQQPLGSIQALGQAMSSAAAYRK--ILSGAVG-AQLPKPPSLPLEPEPEPTVEASPTEASEQK-KEK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RK4-1", "uniprot_id": "BBS4_HUMAN", "id": "Q96RK4-1", "name": "BBSome complex member BBS4", "aln": "------------------------MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLN-QKDWEISHNLGVCYIYLKQFN-----------KAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYD-PTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKC------NPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSS-LEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRT--LPSGAGGTSQFTKPPSLPLEPE--PAVESSPTETSEQI-REK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXH4-1", "uniprot_id": "E7EXH4_DANRE", "id": "E7EXH4-1", "name": "BBSome complex member BBS4", "aln": "------------------------MADDAMRTDVQLPVATELKKPRLKKAPELPILEKRNWLIHLHYIRKDYETCKAIVKEQLHETQGMCEYAVYVQALIMRLEGKIQESLELFQSCAIINPTSSDNLKQVARSLFLLGKHKAAIEVYNEAARLN-QKDWEISHNLGVCYIYTKDFR-----------SAEEQLNLALQLNKHDLTYMMLGKIHLLQGDTEKAIDVYKSAVEFSPENTELLTTLGLLYMQLGKYQKAFEHLGNALTYD-PNNFKAILAAGSMMQTHGDYDVAMNKYRVAAYAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLSPFDWKILYNLGLVHLTMQQFASAFHFLSAAINLRPRMSELYMLLAVALTNLDDAENARRSYEQAVQIDES------SPLVNLNFAVFLYNQGDKKAALLQYQEMERKVNTQLENSSNTEFDPELVEMAQKLGGALQAGENLYWSKPGKDGKTSQRSSS-SKPSGSQQPLGTNQALGQAMSSAAGFSKSMQISAEADVSRAPSPPAGDPEDEDEVEDAAGPAKPKDKKGRAKPVAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8E9-1", "uniprot_id": "BBS4_DROME", "id": "A1Z8E9-1", "name": "BBSome complex member BBS4 homolog", "aln": "-----------------------MYEPGTEQINCNGRLIELPTLEVVRPAPKMPSDANIDWLLHIYFTRREFTRCRRLIERELNRHLNP-EYLYFVQGLIDREEGNHIEALRHLQKSAELNPRNIETYKEIGRTLYIMGRFSQALGVFREAEQRSSRQDHEIYHYLGELLYRAATTQSQKDVASQQQDEARTYFELAVQSGRKLESYVRLAELYRKDKQYQKAIEILENCLHLTPENSEVLIEISVLYLKINETQKAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPEIAELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASEQYASAFHTLAAAINLRKDNAECYMLLGLCLRKLDDMENAFVALERASSMATGQQGAGRNPLVVLNFALFCYETG---RLALSTEQYNRFMSQAQDLLLPTEYKFQATKLKSLLRISNQGNGILLDSADMGESDLGHNRATELLPD--ELPLEVNAVVSQN---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : **.:* : :**:*::: *::: *: :::.:*:. . ** :**.** * **: *:*. :*..* :.* :. *::.*:*:::*:.. * *:.** : . ::* ** * ** .*. :. *:: .:: :*: *.::: : : :***:: :..:.::***:*:* :.:**:::. ***.::*.:.:: : . *.:** *:::*::.* * *:.** * * ** . ******:*** *:*::.***.*::: :*:*:::: ****.*:::: :*:***** *:****:: .* ****.:.* :*:* *** : .* : .*** **:*:: *: * . :: :: : : *:. : .:: . * : * . * : : . :. : . : ** .:.* ", "identical_positions": 129, "similar_positions": 173, "identity": "22.55%" }, { "cls_id": "homologset.agr.MGI:2143315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZLS4-1", "uniprot_id": "A0A8I5ZLS4_RAT", "id": "A0A8I5ZLS4-1", "name": "", "aln": "-MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQG--MDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSLSEEFLALPLEDVLELLSRDELNVKSEEQVFEAALAWIRYDREQRGPCLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAANFYAGDSLNVVEVFDPIANRWEKCHPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVETYSPETDKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFSSVEQYNHHTATWHPAASMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDRWTFMAPMACHEGGVGVGCIPLLTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4F2-1", "uniprot_id": "KLH18_MOUSE", "id": "E9Q4F2-1", "name": "Kelch-like protein 18", "aln": "-MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQG--MDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSLSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPCLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAG-----DSLNVVEVFDPIANRWEKCHPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVETYSPETDKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFSSVEHYNHHTATWHPAASMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDRWTFMAPMACHEGGVGVGCIPLLTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94889-1", "uniprot_id": "KLH18_HUMAN", "id": "O94889-1", "name": "Kelch-like protein 18", "aln": "-MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQG--MDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPYLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAG-----DSLNVVEVFDPIANCWERCRPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLSSVETYSPETDKWTVVTSMSSNRSAAGVTVFEGRIYVSGGHDGLQIFSSVEHYNHHTATWHPAAGMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDCWTFMAPMACHEGGVGVGCIPLLTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGE5-1", "uniprot_id": "Q9VGE5_DROME", "id": "Q9VGE5-1", "name": "Kelch-like protein diablo", "aln": "MDLSDNSQVEDQYFVYKHDKLFGESFPLFKEIRRMGKLCDVTLKVEDQTFSAHRVVLAATIPYFYAMFTNNMAESRIKEITMKESAIEPSALESLINYVYSGQVRIDNQNVQNLMVGASFLQLSNVRDACASFLISRFHPHNVLGIRTFADSMICRQLIDAADKYIDQNFAKVSQSEEFLALDCEQLLELMRRDELNVRTEEVIFEACMKWVKYAEDKRSELFPQVLAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQSFRTRQRSGEFFTGQIYAVGGLASTG-----ESVSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERLSTVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVYYPKSNTWKTVAQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQAEDVWVKMSPMLNRRCRLGVATLNGKIYVCGGYCGNSFLRSVECYDPQTDTWKLVTPMNCKRSRVALAANMGKLWAIGGYDGESNLSTVEVYDPETDKWTFMPPMCAHSGGVGAGVIRIE--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*.:: :: . :. .:* ...: :::**** *********: *:.*****:****:****:*****:* *.: .**.*: ::*****:***:.*.*:: **:****.*::*******..::***.:** .*:**:* **:* **::*:* * ***:.:*.*:*.:** ******* *::***: ******::** :***.: *::* .::*. :*::*: :**** ****:*** :::*:*..*:****:*****:******* * :**** *. ::* ******* *:. :*:..**::**::: *: . *: ********:** ***:**::* ******.*:*..:.*:: :* .****:*...**. ********* :**.:**.* *:::.*..*: * . ***.*** ::* :*. ******.**.***:*:: .* : ***:*** *.*:*..*::***** *..** .* *.. :* * *:.**: :****:*.*. *:*:*:*****:****:**:****** ****.**..*.****.* * : ", "identical_positions": 303, "similar_positions": 185, "identity": "52.06%" }, { "cls_id": "homologset.agr.MGI:2143333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VVU9-1", "uniprot_id": "Q9VVU9_DROME", "id": "Q9VVU9-1", "name": "DNA/RNA non-specific endonuclease domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKCIRFSLLVVGLLAAPAAWARVPCPEVELPPVVEDDGIFERIAVAPPQP--------------------------------VGRAGACSVT----------------------------------IRGG-LPSPEPVYLKT---DSEDFYPFSDVGVMEFESGGSLQLWCPSGFNT------HSENLLT-ASCVSGTTFSVGGSNFEFKDLYCKSWPGFKAVKSGATCNGG-------IVIRVGFEITSSR---FAEQMQICFNEEEEVTRYTRHKLEPGSNYYETGVARITFQTAGFFDGKNVDKLYTQATQLETINNELGGDAEKYFDSSSNVYLARGHLGAKADFDYAPEQRATFLFINAAPQWQTFNAGNWARVEDGLRAWVS--------------KNKLNVNCYTGVYGVTTLPNKDGVETPLYLAKDDNNNGLIPVPKLYFRVVIDP-SSHRGIVFVGVNNPHLTEEQIKRD-YVICDDVSDQVTYINWKTTD-----IKAGWSYACEVADFLKTVKHLP--ALTAKGGLLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVV1-1", "uniprot_id": "Q9VVV1_DROME", "id": "Q9VVV1-1", "name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKCL--VLIAFSGLFLASAQARI-LPAEDLP------WELPEVPVAVNEI--------------------------------EPRAAGCSIK----------------------------------IRSSELKDPQPLLIKS---DTSEIVGFSDTGYVDVDKDKTIEFHCTSSLASP-----LSGKSVT-AKCVGGTTFKIDDKEHDLSAIKCTSWPVFVGKKSGSSCNGGT------TLIKVGFELSGSR---FATQYEVCFNEDEEVTRYVYHRLEPGNNYYATGVDRITFGAGGYFAGKNVDKLYTQAVQKETIDKELDMDSSRFFDSAKNIFLARGHMGAKADFVFAPEQRATFLFINAAPQWQTFNAGNWARVEDGVRAWVA--------------KENKHVECWTGVWGVTTLPNKNGEQRQLYLSHDNNGNGLIPVPKLYFRVVIEP-STKKGIVLIGVNNPHLSLEEIKRD-YILCTDVSDRINWISWKKTD-----ITAGYSYACEVPEFRKKVTHLP--EFSVSG-LLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU22-1", "uniprot_id": "Q9VU22_DROME", "id": "Q9VU22-1", "name": "DNA/RNA non-specific endonuclease domain-containing protein", "aln": "MWSNRCSIFILALLVASGAVKVSGRLPRILPESLAEGDEGVTVRGDCEFKVNGDLNDPAPLFSRHNSYEIIVPDPTDTVRLVNGELLDMFCPGVGFAAPFVNRWQVTATCLQNKYFLVDDLIYPFANFSCTAWPIFTALRSGKDCNGGTDLVQVGFEVEDGGFLQSYELCHDAEAEATRYVHHVLYPSSYDYQHGVARPNFLELDFYGGRDVNTKYTQVQQNITISNILGLDASPYFNFSDDRILSRGHMIAKTDQIFGAAQHTTFLFINVAPQWQTFNGGNWEKVETSVRKFVADRNLTTDCYTGTWGVSTLPDVDGIERELYLDFDENNNGLIPVPKIYFRVVIDRVTREGIVLIGINNPYLTLEQIQKDYILCQDIGHQLSWLTWYKEDLHEGYSYACSVEDFIEVVKDLPLEDLHTNGILGLDDVTTVEPSTTESSTTTEEPSSTTSTEIPSTTDTTPSSTSVSSTTEEPSSSTASPTTELPTSTVISTTEPPTSTVTSTTKPPTSTVASTTEQPTSTVTSTTEPPTSTVTPTTEPPTSTVTSTTEPSSSTTLEPTSTTSSSTTSQPTLSTEESTSTSPTSTSTSSPPVTTANPIANPCRFSTNGDLKDPAPLLTPQGALSWLLPDESGLYTVEEGSSIDLHCTGALVSPFNRYTALSARCVGDQLYEAEGQLVNIRGFVCQSWPTYAAVRSGQSCAGGTDVVHIGFDVAAGFLSHVELCYDQQEQISRYARYELTPANVAYQKGVAQPGYLRGDFYSGEDVNVLYDQSHQLDAFSTALGLDASQYFDSTKDLYLTRGQLAARLDFVHSSAQRATHFYVNAVPQWRSINIGNWLAVESSLKQFVADEALNVSVHAGSYDISTLPNSQGVQTPLYLNAETKQLPVAKILYRIVIDQESRKGVVLIVVNNPHITLTETLEDYVICEDVGAQIDWLDWDKANLQKGYSYACSVEDFIEVVKDLPTDQLQTTGILGLTDQILDNEVCSFKVNGDLKDPAPLFVVRSELGHARYLEPNQEGVVQLKHGEALEFHCINSFSGP-----FSGYTFVNSTCWQQQSILAMGSLYQLQDFVCTSWPTYTARRSGRPCNGGT------DLLEVGFQLSSSSSDDFLQTYDVCHDELSEVTRYVHHVLYPGSDQYQRSVSRPSFIPGDFYGGKDVNTLYTQVQQNITVSEILGMDASPYFNTTGNVYLARGHLSAKTDFVFGAAQKASFFFVNAAPQWQTFNGGNWERIEDSVRKFVA--------------DENITVDCYTGTWGVSTLPDVNGIGRELYLDFDENNNGLIPVPKLYFRVIIDR-ESRNGIVLLGVNNPHATIEQIEEE-YIICQDIGAQLSWVSWTKED-----LKKGYSYACTVEDFTAVVKDLPLQDLFVDGVLGV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU24-1", "uniprot_id": "Q9VU24_DROME", "id": "Q9VU24-1", "name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMLQFIGLILAVVILREIRAREAIATIPDVGQIIKDLDGLHIDGEMFHQ---------------------------------GSPCRVDVQN----------------------------------DLPRLDKVQPLYLRP---GTDLYWLPNAYGHLEVQRGASIELHCSHSFAPANGESLDAKLRSIRVKCVQDTTFEWMGAKIHFSDFVCNHSMPYTVERLDRSCGSDTPSPSTSYLYRVGYDTGDGR---FVATMELCHDPNQLRTHYAHHQLTPANVHFQKKLKRPRFSTAGHFTGFDMARIYSPKSQEK-------LMVPGLIDVKSGLFLARGHLTAKADLIYASQQKSSFNYMNVAPQWQSFNGGQWSKLEESTRQYVA--------------RSGITATVYTGIYGEMKVAG----SKVLHMTTNANNIGVVAVPQLFYRVLIDEGHPTRGIALVGVNNPHATLAQIHES-YIICDPVEESVQWLSWLHKSNAKGNLKNGYLYACSVANLARAVGHLPRPLLEVDELLT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAU2-1", "uniprot_id": "Q9VAU2_DROME", "id": "Q9VAU2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDLKYMLTILSLYFFVGSVQANCLIDLAHL------------------------------------------------------------------------------------------------------------------NANYVYLSQNNGVYDIQRSDIVEIHQTLYLLCN------GGLHRTTFLCRYDSVFSP-----ALSSAACAPPDPVVVKVPDTSCSIPS------ATFAVGFSFNGR----FMELYRNCFDGYSLAFQHSIYKAYRYVNTVPR--PNPTWQSDQLSGG--FDNAYEGRATQACLLTNLG-------AVQPQCKFDRGHMTPASAFISTELKKSTFRYLNAIPQYRGVNRGKWKAVETWVNNMVRGLYDNPIINNVQIPRTYDVLKVCIGALGVHRLRHN---TNNNMIPIYLLDNNKIPVPEWMYKIVSHLS-GDKWVMLTYND---VSLPNQQAL-NQICH-VIPCHPGLNLNTKD-------VGHTVCCDPYRFITINAPHLTGVC--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KRX0-1", "uniprot_id": "Q7KRX0_DROME", "id": "Q7KRX0-1", "name": "Endonuclease", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMHELRYLIITLSLFLTVGNVKSFCQITQAET------------------------------------------------------------------------------------------------------------------WTDRLFVHIVNNRYELLLTDQLQPNQQISLLCD------GNAQVFTSTCRNNGQFSP-----PLPRTNCSKAIPPSV-VPTSSNICPH------TMYLVGFKYGNT----FMELYRSCYDARTMKAYFSINTVYPTNLKSDR--PPTVFDKDGIITP--ADEATFQMNSIYNRFEYLFGSGQTYVPSSRSLSFDRGHLTPVADYSFPKILRQTNKYLNVVPQYYNINRSNWKIVENWVRGQK------------------DVLNVCTGALGVLDLLNR---SQK-SVSIYLAPN-KNPVPRWTYKIIRSLTTGIKYVILTSNN---GWETQQPNP-ASVCK-VTACPR--TLNPTG-------TGYTFCCDPIDFIRRNVPNLAGVCWDNTENV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZTW9-1", "uniprot_id": "D3ZTW9_RAT", "id": "D3ZTW9-1", "name": "Nuclease EXOG, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAKGFASRLRDSRRFLNGFLAGAVVGAAGAG----------------------------------------------------------------------------------------------------------------LTALQFLQRRDAGSARPARQPHESVEKVVLEQFG------FPLTGTETRRYTN---------HALSYDQAKRVPRWVLEHISKDKIIGD-----ADRKHCKFKPDPT----VPSAFSALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQN-FENNSGYWNRIEMYCRELTERFEDVWIVSGPLTLPHTRNDGTKTVSYQVIGEDNVAVPSHLYKVILARRSPESTEPLALGAFVVP----------------------NKAIGFQSQLS----EFQVSLHDLEKMSGLVFFPHLDRTRDIRNICSVDTCKLLGFQEFTLYLSTRKIDGARSVARLEKVLEALKSSGVE------PDDYFLSRYGKKLEELKAKEQKDAQLEKQS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C163-1", "uniprot_id": "EXOG_MOUSE", "id": "Q8C163-1", "name": "Nuclease EXOG, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAKSFASRLRDSRRFLNGFLAGAVVGAAGAG----------------------------------------------------------------------------------------------------------------LTALQFFRRPDAESAKLARQPHESAEEAVLEQFG------FPLAGTETRRYTN---------HALSYDQAKRVPRWVLEHISKDKIIGD-----ADRKHCKFKPDPS----VPSAFSALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQN-FDNNSGYWNRIEMYCRELTERFEDVWIVSGPLTLPHTRNDGTKTVSYQVIGEDNVAVPSHLYKVILARRSPESTEPLALGAFVVP----------------------NKAIGFQSQLS----EFQVSLHDLEKMSGLVFFPRLDRSRDIRNICSVDTCKLLGFQEFTLYLSTRKIDGARSVARLEKVLEALKSSGVE------PDDYFLSRYEKKLEELKAKEQKDAQLEKQS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2C4-1", "uniprot_id": "EXOG_HUMAN", "id": "Q9Y2C4-1", "name": "Nuclease EXOG, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAG----------------------------------------------------------------------------------------------------------------LAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFG------FPLTGTEARCYTN---------HALSYDQAKRVPRWVLEHISKSKIMGD-----ADRKHCKFKPDPN----IPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQD-FDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVP----------------------NEAIGFQPQLT----EFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIE------PDDYFMSRYEKKLEELKAKEQSGTQIRKPS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAU3-1", "uniprot_id": "Q9VAU3_DROME", "id": "Q9VAU3-1", "name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRILLLLLAFCALAHGQCRFTRAQVQGTN-------------------------------------------------------------------------------------------------------------------RIFMVRGQNRQLSLKRTASSAVGETLQMWCN-------PRDIVATTCQAGRVP-----AFQPPLPMTCRAAPAAITTPVQDRRCPA------TMYRVGYNVGNNQ---FLELYRACFDTRAVRAIFVEHRVYGKPFYITR--PCVQFSSDGVISG--ADEASYTVRNIHGTFRRLFGNNQNYIPNNRDVIINRGHLAASADFFFGDQLCATFKYVNAVPQFKSINDGNWETIERFVRNSVTG---------------NNFVNVRTGARGVLSLPSG------NRPKNVFLSGNRNPVPQWMYKIVRNANNQPIVAFLTLNN----IYARQRPAAPNFCQPVNCPVALVNTAQAG---------FSFCCNPATFRP------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : : : : . . : . . * .*. : : : . . : ", "identical_positions": 2, "similar_positions": 21, "identity": "0.14%" }, { "cls_id": "homologset.agr.MGI:2143340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAK3-1", "uniprot_id": "D3ZAK3_RAT", "id": "D3ZAK3-1", "name": "Zinc finger protein 445", "aln": "MPPGRCYAAR--SVQMSREHGRLHMVKKEEEEDGCISVETARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLQELCRWWMRPDVLSKAQMLELLVLEQFLSILPGELRTWVQLHCPESGAEVVALLEELQRDLDGTSLKDSCLTQNPDVHWIGTGPLQAAQIWSPASHVGKSSALEDYLETPHGIG----EVVLTHSPAVSMPDYFQIEES------------IEHQETLTFQDVEVTFSQEEWGCLNSAQRNLYRDVILENYGNVVSVVGSSPKPALISWLEARKPWGMNICTVQLKREPDAAPEGGKLQIEPSKFILKQEPSKYTETCVKPSGCPAS---KGTGLKESFEQKSRLQKSCGDSVQMKEMKKGTDISQKAGRKSEILRNSDILELKHVKCVSVSRKKLSFKHGYDRNFRKSSHHYN-NKYGEGLRDTVEGFGVYQ--NTGLKENEKDRCGETLRKSSH--------------------------SHLEYQR-YYSQGSLFKCRVCEKAFKWRSNCIRHEKIHTGVKPYKCSSCEKAFQRLSTYRLHQKTHTKQK-HESRKYNNALPCSLDVSHCLINQDEEKNFYCSQCGKHFSCRSYALEHQRIHTQEKPYNCIRCRKTFRWKSNFTRHMKLHG-KEVRNQERCQEDFKQN--YSQSQVISTIEKTFLCQSCGKTFTQKKSLIEHQRIHTGEKLYQCSGCGKTFASRSSYIIHMKQKRHAIKIKPESGSLPFSQDTAFAIPQSGHNTEEPNQCKYCGRAFHNRSFLLIHERIHTREKPYKCRECEKAFRWRSNLYRHERKHFLHKRRKYHESKETSNLQSKIFIDEKPFWCQECGKTFTRKRSLLDHKGIHSGERRFKCNLCEKSFDRNYRLVNHQRIHTTEQPFQSQWHDKDFAGTHAHSVDQRKHR-TLQSEYSLQSDKPGLSYCQDVRVNIQELELSGKKPLDNPSHESSMSTAFQNVPT---KKACHKCSTCGKTFRKHSHLISHKRCHTKERPFKCIVCGKTFGWSSNLTRHVKSHFRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2V3-1", "uniprot_id": "ZN445_MOUSE", "id": "Q8R2V3-1", "name": "Zinc finger protein 445", "aln": "MPPGRWHAAR--SAQVSREQGCLRMVK-EEEEDGYISMQTARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLQELCRWWMRPDVLSKAQMLELLVLEQFLSILPGELRTWVQLHCPESGAEVVALLEELQRDLDGTPLKDPCLTQNPDVHWIGTSALQPAQIWSPASHLKNSSALEDHLETSHGIGICDVLAEQTDSPAVSVPDYFQLEEG------------IEYQEALTFQDVEVTFSQEEWGCLNSAQRNLYRDVILENYGNVVSVVGSSPKPALISWLEARKPWGVNICTVQLKRDADAAPEGGKLQIKPNKFILKQKPSEYIEACVKTSVSPETSVSEETGLKESFKQKSRLQTSCGDSIQMKEMKEGADISQRTGRESEVLRNNDILELKHVKCVSVSRKRLSFKHGYDRNFRKSSHHYN-NKYGEGLRGTGEGFGVYQ--NTGLKENGKDRYGETSRKSWH--------------------------AHPEHRQPSYSEEGLFQCRVCGKAFKWRSNRIRHEKIHTGVKPYQCSLCEKAFQRLSSYRLHQKTHSKQK-RGSSKYKNALTCSLDVSHHLTDRDERKHLHCNQCGKNFSCKSYAIEHQRIHTQEKPYKCTRCRKTFRWKSNFSRHMKLHH-KEVYKQEKRQEDFKQS--YRQSQVISTVEKTFPCQNCGKTFTQKKSLIEHQRIHTGEKPYQCSGCGETFTYRSSYIIHMKRTQHAIKIKPEHGCLTFSQGAVFPIPRGSHNTEGSNKCKYCGKAFHNRSFLLIHERVHTREKPYQCRECEKAFRWSSNLYRHQRKHFLHKRYKYRESKETSNLQSKILIDQKPFWCQECGKTFTRKRSLLDHKGIHSGERRFKCNLCEKSFDRNYRLVNHQRIHTTEQP---QWRDKDFVGIHARSVDQRKHSNTLQSEYGLHSDKPGLSYCQDVRLNIQELSGKLRKECDNPSDESSKSIAFQNVPTK--KKACHKCSTCGKTFKKHSHLISHKRCHTKERPFKCIVCGKTFRWSSNLTRHMKNHVRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59923-1", "uniprot_id": "ZN445_HUMAN", "id": "P59923-1", "name": "Zinc finger protein 445", "aln": "MPPGRWHAAYPAQAQSSRERGRLQTVKKEEEDESYTPVQAARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLRELCRWWLRPDVLSKAQILELLVLEQFLSILPGELRVWVQLHNPESGEEAVALLEELQRDLDGTSWRDPGPAQSPDVHWMGTGALRSAQIWSLASPLRSSSALGDHLEPPYEIEARDFLAGQSDTPAAQMPALFPREGCPGDQVTPTRSLTAQLQETMTFKDVEVTFSQDEWGWLDSAQRNLYRDVMLENYRNMASLVGPFTKPALISWLEAREPWGLNMQAAQPKGNPVAAPTGDDLQSKTNKFILNQEPLEEAETLAVSSGCPATSVSEGIGLRESFQQKSRQKDQCENPIQVRVKKEETNFSHRTGKDSEVS-GSNSLDLKHVTYLRVSGRKESLKHGCGKHFRMSSHHYDYKKYGKGLRHMIGGFSLHQRIHSGLKGNKKDVCGKDFSLSSHHQRGQSLHTVGVSFKCSDCGRTFSHSSHLAYHQRLHTQEKAFKCRVCGKAFRWSSNCARHEKIHTGVKPYKCDLCEKAFRRLSAYRLHRETHAKKKFLELNQYRAALTYSSGFDHHLGDQSGEKLFDCSQCRKSFHCKSYVLEHQRIHTQEKPYKCTKCRKTFRWRSNFTRHMRLHEEEKFYKQDECREGFRQSPDCSQPQGAPAVEKTFLCQQCGKTFTRKKTLVDHQRIHTGEKPYQCSDCGKDFAYRSAFIVHKKK--HAMKRKPEGG-PSFSQDTVFQVPQSSHSKEEPYKCSQCGKAFRNHSFLLIHQRVHTGEKPYKCRECGKAFRWSSNLYRHQRIHSLQKQYDCHESEKTPNVEPKILTGEKRFWCQECGKTFTRKRTLLDHKGIHSGEKRYKCNLCGKSYDRNYRLVNHQRIHSTERPFKCQWCGKEFIGRHTLSSHQRKHTRAAQAERSP----PARSSSQDTKLRLQKLKPSEEMPLEDCKEACSQSSRLTGLQDISIGKKCHKCSICGKTFNKSSQLISHKRFHTRERPFKCSKCGKTFRWSSNLARHMKNHIRD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** :** ..* ***:* *: ** ***::. .:::************************************:******:*********:******************.***** **** *.**************. :*. :*.*****:**..*:.***** ** : .**** *:**..: * . :.:**..:* * * : **::**:********:*** *:**********:**** *:.*:**. .***********:***:*: :.* * :. *** *..** :..****:*:* : *: . .* .* : : **:***:**** : .* :.:*:: *: :::*:::*:.**: ..: *:****. : ** :: *:*** .::** *****: :***:*** **.::* ::*** * ** *: * * :* ::: ::: *:**** ***:* ** ************:*. *****:***:****::**:*:* :*. **. * ...* * ::. .* : *.** * * *:**.:************:* :*******:***:***:** ::. :*:. :*.*:*. *.* .::**** **.******:**:*::********* ****.**: *: **::*:* *: **:* *** * .***.:.* :*:..*..* . :*. **:**:*:******:*:** ****:**** ***** ******:* * *:*: . :**::*.*::.**: .:* **************:***********:*:***** **:*************:**:* ** .*:* * *: * .**** : *:* . *. * .**.::.:*:*. . . :: .. .* * : .: * ***** *****.* *:****** **:****** ***** *****:**:*.*.*:", "identical_positions": 556, "similar_positions": 250, "identity": "53.51%" }, { "cls_id": "homologset.agr.MGI:2143362", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VG72-1", "uniprot_id": "Q9VG72_DROME", "id": "Q9VG72-1", "name": "Zinc finger protein 865", "aln": "MDLANVDQRPVKDEPPQEDTFEEELIFISNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCKSKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLR-THQEARPFKCSHCSKSFKLRSILQKHLLTHAERS--FKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLRRTLCGTKSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "G3X9G7-1", "uniprot_id": "ZN809_MOUSE", "id": "G3X9G7-1", "name": "Zinc finger protein 809", "aln": "---------------------------MGLVSFEDVAVDFTLEEWQDLDAAQRTLY-RDVMLETYSSLVFLDPCIAKPKLIFNLERGFGPWSLAEASSRSLPG--------VHNVSTLSDTSKKIPKTRLRQLRKTNQKTPSEDTIEAELKARQEVSKGTTSR--HRRAPVKSLCRKSQRTKNQTSYNDGNLYECKDCEKVFCNNSTLIKHYRRTHNVYKPYECDECSKMYYWKSDLTSHQKTHRQRKRIYECSECGKAFFRKSHLNAHERTHSGEKPYECTECRKAFYYKSDLTRHKKTHLG----------------------------EKPFKCEECKKAFSRKSKLAIHQKKHTGEKPYECTECKKAFSHQSQLTAHRIAHSSENPYECKECNKSFHWKCQLTAHQKRHTG-----------------------VTYFQEVVFQQITVSDWTGNLSENGPHRPTWT--WAYGIMDFVKAWS-RCIIGGGL----------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .**:: ::.:*:: . . ..: *:* .* : . : * . *: : .:: * . * : *. . .: : *:: ::.:: : ...*: : . :*.: : * .* : .*:.***: : ::.: . :**..***.* *** * :* * **: :*::*..*** : :* * .* ** :*. ::*::* *:*:::. *: * *.*:**.*::*..* ::* :* * * * * *: :** **.*:* :**:*. **: ****:*::**.* * *. :::* .* : * .*: :*. *.*.*: ..** .* :.*** *: *: *: *. .. :*: * * * .* . . :: :. :* * ", "identical_positions": 111, "similar_positions": 146, "identity": "22.02%" }, { "cls_id": "homologset.agr.MGI:2143424", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NDF0-1", "uniprot_id": "PMGT2_RAT", "id": "Q5NDF0-1", "name": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "aln": "MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALGQQSLDPVPGLRIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNSSVMLPNLGSRRFQPALLDLSTVEDHNAQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAQEARLFFMEGWGEGAHFDLYKLLSPKQPLLRSQLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLNVSHAGAPLGEEYILVFSRTQNRLILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVAWRNMIRENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTRVDIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQIPWNLKYLKVREVRYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNRSLLGPFADVLVCST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BW41-1", "uniprot_id": "PMGT2_MOUSE", "id": "Q8BW41-1", "name": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "aln": "MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALGQQSLDPVLGLKIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNSSVMLPNLGSRRFQPALLDLSTVEDHNAQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAQEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLNVSHAGAPLGEEYILVFSRTQNRLILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVAWRNMIRENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTRVDIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNRSLLGPFADVLVCST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NAT1-1", "uniprot_id": "PMGT2_HUMAN", "id": "Q8NAT1-1", "name": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "aln": "MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLSTVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKITTWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLILNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGATVVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGLYPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILALQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5NDE5-1", "uniprot_id": "PMGT2_DANRE", "id": "Q5NDE5-1", "name": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "aln": "MNLPAVLNGLLVSVVAALLWKYVRLVEHTSQLEEELQLTRQSQE-FSQVRIDYHGALLALQEHGTRMVCTGKMHTDRICRFDYLCYCTEAEEFVFFHSNASVMLPNLGSRRFQPALLDLSSVEDHNTQYFNFLELPAAALKFMPKPVFVPDVTLILNRFNPDNLMHIFHDDLLPVYYTMQQYSDLDDEARLVFMEGWGEGAHFDLYRLLSSKQPLLKDQLKTFGKLMCFTKSYVGLSKMTTWYQYGFVQPQGPKANILISGNEIRQFASFLMERLNITREEEEEDDDYIVVFKRTTNRLILNEAELLLALAQEFQMRTVTVSLEEQSFDNIIQIISRAAMLVSMHGAQMITSMFLPRGAAVVELFPYGVNPEQYTPYKTLASLPGMDLQYVAWRNTMEENTVTFPDRPWDQGGIVHLEKEEQERILASKEVPRHLCCRNPEWLFRIYQDTTVDLASFLDVLRDGLK-KLNLKKAKVASTVHPGRVREPKCQTSVQATNEAKLSVSWQIPWNLKYLKVKEVKYEVWIQEQGENTYMPYILPHQNYTFSENIKPFTTYLVWVRCIFNKNLLGPFADVLICKT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.**:*.*****:**:***:*** **:: ***** * :*: : ::*** ** * * **:*****: ********.:***..*****:***.*:********************:*****:*****:*******:***********:** **********:*******::**::*:..* .****.**************:***.*****: ****:*:*:**::::*****:*******************:********: *: *:**::: .::**:**.** ************ *******:*******:::* ::::::*.*:*********::*::******:*******.***::******** ************* : *****.*:********.**:: ** *** *:********************* **:.*::: :* :* : . :: : : ::**:***.:**:**:.:.**:*:**************:**:****:********:**:*. **:**:******************: *********:*.*", "identical_positions": 408, "similar_positions": 124, "identity": "70.34%" }, { "cls_id": "homologset.agr.MGI:2143484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08469-1", "uniprot_id": "S6A15_RAT", "id": "Q08469-1", "name": "Sodium-dependent neutral amino acid transporter B(0)AT2", "aln": "MPKNSKVVKRDLDDD-VIESVKDLLSNED-------------------------------------------------------SVEDVSKKSELIV-DVQEEKDTDAEDGSEVDDE-----RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWTLFYFSQSFQQPLPWDQCPLVKNASHTYIEP-ECEKSSATTYYWYREALAISSSISESGGLNWKMTGCLLAAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLEMMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIVNEKCISQNSEMILKLLKTGNVSWDVIPRHINLSAVTAEDYHVVYDIIQKVKEEEFAVLHLKACQIEDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPVVDT---FKVRKEILTVICCLLAFCIGLMFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYGIDKFLEDLTDMLGFAPSKYYYYMWKYISPLMLVTLLIASIVNMGLSPPGYNAWIKEKASEEFLSYPMWGMVVCFSLMVLAILPVPVVFVIR--RCNLIDDSSGNLASVTYKRGRVLKEPVN----LDGDDASLIHG-------KIPSEMSSPN-FGKNIYRKQSG-SPTLDTAPNGRYGIGYLMAD---MPDMPESDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG16-1", "uniprot_id": "S6A15_MOUSE", "id": "Q8BG16-1", "name": "Sodium-dependent neutral amino acid transporter B(0)AT2", "aln": "MPKNSKVVKRDLDDD-VIESVKDLLSNED-------------------------------------------------------SVEEVSKKSELIV-DVQEEKDTDAEDGSEADDE-----RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWTLFYFSQSFQQPLPWDQCPLVKNASHTYVEP-ECEQSSATTYYWYREALDITSSISDSGGLNWKMTVCLLVAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLEMMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIVNEKCISQNSEMILKLLKMGNISWDVIPHHINLSAVTVEDYRLVYDIIQKVKEEEFAVLHLNACQIEDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPIVDT---FKVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYGIDKFIEDLTDMLGFAPSKYYYYMWKYISPLMLLTLLIASIVNMGLSPPGYNAWIKEKASEEFLSYPMWGMVVCFSLMVLAILPVPVVFIIR--RCNLIDDSSGNLASVTYKRGRVLKEPVN----LEGDDASLIHG-------KIPSEMSSPN-FGKNIYRKQSG-SPTLDTAPNGRYGIGYLMAD---MPDMPESDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2J7-1", "uniprot_id": "S6A15_HUMAN", "id": "Q9H2J7-1", "name": "Sodium-dependent neutral amino acid transporter B(0)AT2", "aln": "MPKNSKVVKRELDDD-VTESVKDLLSNED-------------------------------------------------------AADDAFKTSELIV-DGQEEKDTDVEEGSEVEDE-----RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTFVEP-ECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANVINEKCITQNSETIMKFLKMGNISQDIIPHHINLSTVTAEDYHLVYDIIQKVKEEEFPALHLNSCKIEEELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDT---FKVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASEEFLSYPTWGLVVCVSLVVFAILPVPVVFIVR--RFNLIDDSSGNLASVTYKRGRVLKEPVN----LEGDDTSLIHG-------KIPSEMPSPN-FGKNIYRKQSG-SPTLDTAPNGRYGIGYLMADI--MPDMPESDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVQ4-1", "uniprot_id": "Q1LVQ4_DANRE", "id": "Q1LVQ4-1", "name": "Transporter", "aln": "MPKNSKTIKREIDDDDVTESVKDLLSNED-------------------------------------------------------SCDDSFKKSSLMVGDVPQNKQKDVEEGSEEEEEEEEEERPAWGSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPLFFLELAVGQRIRRGSIGVWNYISPHLGGIGFASCLVCFFVALYYNVIIGWSLFYFSQSFQQPLPWHECPLVKNKTNTYIEP-ECEKSSATTYYWYRVALDISDSISEGGGLNWRMTLCLLAAWTMVCLAMIKGIQSSGKVMYFSSLFPYVVLICFLARAFLLKGSVDGIIHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIMNAKCVEMNTKKIIGFLGK-EINPGLIPHHINFSQVSPEDYQQMTNIIQGVMENDYPRLGLDNCDIKEELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIQGILTPIVDT---FKVRKEYLTVGCCVLAFFIGLTFVQRSGNYFVAMFDDYSATLPLLIVVLLENIAVAWVYGTDKFFEDLKDMLGFTPYRYYYYMWKFVTPVLLLGLLAASVIQLGLAPPSYSAWNQQLAKEQSLSYPPWGLAVCISLVVTAILPVPVVFILR--CLNIIDEKTGGLSTVSYKKGRIIKDTACRTREDDEDDASLLNA-------KTPSEAPSPM-PAN--YRKQSGPASAADAKLNGSCSTGYLMPNITDIPDMPESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7V4-1", "uniprot_id": "A0A0B4K7V4_DROME", "id": "A0A0B4K7V4-1", "name": "Transporter", "aln": "-----MAATKIIDAP---RNGHEMAPLNT-------------------------------------------------------RARGDGTHGVTIVLTAPQRNSVQSVDIPGNEPE-----RAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLNGTG---FELE-ECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVK--------------NKLLGLNDTQGYEQAMSLLNGT---ELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFLMRSFQCLKVDLDIHQGSIRRNETTASTKEMIDNDDDDDEDDENDFSGPALGGHVKTQSDFSDDDEEDKPMTMRMMMMRPTTTTKTSNVLNVPTSRKNN---YKKEAYDV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z122-1", "uniprot_id": "B7Z122_DROME", "id": "B7Z122-1", "name": "Transporter", "aln": "MANTAQLLRRQSSRDIILKSQKSIDQLELRELRGRLVSKEHGVSHHHHTSLHHQPLYGATNQGFMSDAFDESSELEQDPPPFGSEASTSKAKAELVAIATASADQQDIVEGEKEGEE-----RESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWADCPTRLYKNFTYDHEPECVASSPTQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERN-----------------------GLVAQN-----------------KTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNLPKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCWKYLSPCAMVTILLASFYQLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIVAVLRLCGIKVVEDSDPAWFP--------------------EAELREVHG-------IVPHEPTELE--RSIFCFNMDG--------TEGMCCPKYGLPEK----SLEEEE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. :.: : . :. . .. : : * * :*..*: ::*: :*::*****:******.*:*****:*:*::::* : ***:* :**.:***:* *::***. : * *****::*.:* :******.** * ::*: :**. **** .** : ** ** * ::*** :* : *:. .::: :. .*: :* :* : :::** ****::*::::***:** *: *.: *.*: *: *::**: * :*:* ** :*.**:*:::**.**.:***.*** .*** *.:***. * *:: * :*:*:::****. :* .. . : * *.: ** ::..******* **:*: .:*.: :*:*:** **..**:.* :* ::*:: .:.* .: *: :. *. . :.: * :*.* . ::*.::..: *:::.::* ::: ::** :* :*: * * * *: : *::: * :: :* :*. : . * ** . . : .:* * : :.. ::: .:* :*:* ::* :: . : . . : .. . . .. : . : ", "identical_positions": 191, "similar_positions": 231, "identity": "23.49%" }, { "cls_id": "homologset.agr.MGI:2143526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKZ0-1", "uniprot_id": "A0A8I6GKZ0_RAT", "id": "A0A8I6GKZ0-1", "name": "glutathione transferase", "aln": "MGGKTGIELRSRLRSTEGLRPSRSCSPLQLLLPLSTEAVHPRPISEVCQRLLPTASAMGLELYLDLMSQPCRAVYIFAKKNGIPFQLRTIELLKGQHYTDAFAQ-VNPLRKVPALKDGDFVLAESVAILLYLSRKYKAPDHWYPQDLQTRARVDEYLAWQHTALRSCCSRAMWQKMMFPVFLGQPVP-PERLASTLAELDGCLQMLEDKFLQNKAFLTGPHISVADLVAITELMHPVSAGCKIF-ESRPKLAAWRQRVEAAVGESLFQEAHEVVLKAKDMPPLMDP-TLKEKLKLSVQCLLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99L20-1", "uniprot_id": "GSTT3_MOUSE", "id": "Q99L20-1", "name": "Glutathione S-transferase theta-3", "aln": "---------------------------------------------------------MGLELYLDLMSQPCRAVYIFAKKNGIPFQLRTIELLKGQQYTDSFAQ-VNPLRKVPALKDGDFVLAESVAILLYLSRKYKAPDHWYPQDLQTRARVDEYLAWQHTALRSCCTRAMWQKMMFPVFLGQPVP-PEMLASTLAELDGCLQVLEDKFLRNQAFLTGSHISVADLVAITELMHPVSAGCKIF-ESRPKLAAWRQRVEAEVGESLFQEAHEVVLKAKDMPPLMDP-ALKEKLKLSVQCLLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZ94-1", "uniprot_id": "E7EZ94_DANRE", "id": "E7EZ94-1", "name": "glutathione transferase", "aln": "---------------------------------------------------------MPLELYLDLHSQPCRSVFIFAKINKIPFEYKAVDLSAGEQYGDEFGK-VSIIRKVPALKDGDFLLTESIAILLYLAGKHSTPDHWYPADLQKRAQVDEFLSWQHTNIRSHGSKVFWFKGVLPAVTGAPVP-KEKMDSALEDLNMSLKIFEDKFLQSRPFIIGDKISLADIVAIVEMMQPVATGVDVF-EGRPALSAWRDRVKKEVGVELFDEAHKVIMNVESLPQTFENKGLPEFFKLKIQKMFN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JJS1-1", "uniprot_id": "E1JJS1_DROME", "id": "E1JJS1-1", "name": "glutathione transferase", "aln": "-------------MSVSFLASLLGLSNDEDQLQVAFDEVLKRRVPSRQPTNLR--MSAPIRYYYDLMSQPSRALFIIFRLSNMPFEDCVVALRNGEHLTEDFKKEINRFQRVPCIHDNGYKLAESVAILRYLSAKGKIPEHLYPKYFVDQSRVDEFLEWQHMSLRLTCAMYFRTVWLEPLL-TGRTPSEAKIETFRMQMERNLDVVEEVWLEGKDFLTGSSLTVADIFAACEIEQTRMADYDVR-IKYPKIRAWLKRVRQSCNP-YYDVAHEFVYKISGTGPQAKL----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7X7-1", "uniprot_id": "A1Z7X7_DROME", "id": "A1Z7X7-1", "name": "", "aln": "-------------------------------------------------------MSKPIRFYYDLLSPIARGLWIGLKFSNSPVEYCPIALRKFEQLTDEYKK-INRFQKVPAIVGGDFHLSETIAIIRYLADKGQFDEKLYPKTLENRARVDEFLEWQHLNIRLACSMYFRDAWLFPMNGIAPKPKPEQIQALIEGVENNLGLLERLWLEN-DFLVGKNLTMADILGSSEINQLRLCQYRVDEKKFPKVVKWLERVRVSANP-YHDEGLTFIDRKSKQSTAAKL----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * ** * .*.::* : . *.: : * :: : : : :. :::**.: ...: *:*::**: **: * . :: ** : :::***:* *** :* : : : * * : : :: * :.* :*.. *: * :::**:.. *: : : * : * .**. . .: . .: . . . ", "identical_positions": 41, "similar_positions": 75, "identity": "13.58%" }, { "cls_id": "homologset.agr.MGI:2143535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VC97-1", "uniprot_id": "BUP1_MOUSE", "id": "Q8VC97-1", "name": "Beta-ureidopropionase", "aln": "MAGPEWQSLEQCLEKHLPPDDLAQVKRILYG-KQTRNLDLPREALKAASERNFELKGYAFGAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKSIEEIAEVAAMCGVNIICFQEAWNMPFAFCTREKLPWTEFAESAEDGLTTRFCQKLAKKHNMVVVSPILERDREHGGVLWNTAVVISNSGLVMGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCALNRVGQEHFPNEFTSGDGKKAHHDLGYFYGSSYVAAPDGSRTPGLSRNQDGLLVTELNLNLCQQINDFWTFKMTGRLEMYARELAEAVKPNYSPNIVKEDLVLAPSSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03248-1", "uniprot_id": "BUP1_RAT", "id": "Q03248-1", "name": "Beta-ureidopropionase", "aln": "MAGPEWQSLEQCLEKHLPPDDLSQVKRILYG-KQTRNLDLPRKALEAASERNFELKGYAFGAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKRIEEIAEVAAMCGVNIICFQEAWNMPFAFCTREKLPWTEFAESAEDGLTTRFCQKLAKKHNMVVISPILERDRDHGGVLWNTAVVISNSGLVMGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSVNGAEIIFNPSATIGELSESMWPIEARNAAIANHCFTCALNRVGQEHYPNEFTSGDGKKAHHDLGYFYGSSYVAAPDGSRTPGLSRNQDGLLVTELNLNLCQQINDFWTFKMTGRLEMYARELAEAVKPNYSPNIVKEDLVLAPSSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBR1-1", "uniprot_id": "BUP1_HUMAN", "id": "Q9UBR1-1", "name": "Beta-ureidopropionase", "aln": "MAGAEWKSLEECLEKHLPLPDLQEVKRVLYG-KELRKLDLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI04-1", "uniprot_id": "Q9VI04_DROME", "id": "Q9VI04-1", "name": "Beta-ureidopropionase", "aln": "MSAFELKNLNDCLEKHLPPDELKEVKRILYGVEEDQTLELPTSAKDIAEQNGFDIKGYRFTAREEQTRKRRIVRVGAIQNSIVIPTTAPIEKQREAIWNKVKTMIKAAAEAGCNIVCTQEAWTMPFAFCTREKFPWCEFAEEAENGPTTKMLAELAKAYNMVIIHSILERDMEHGETIWNTAVVISNSGRYLGKHRKNHIPRVGDFNESTYYMEGNTGHPVFETEFGKLAVNICYGRHHPQNWMMFGLNGAEIVFNPSATIGRLSEPLWSIEARNAAIANSYFTVPINRVGTEQFPNEYTSGDGNKAHKEFGPFYGSSYVAAPDGSRTPSLSRDKDGLLVVELDLNLCRQVKDFWGFRMTQRVPLYAESFKKASEHGFKPQIIKET--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. * :.*::******* :* :***:*** :: :.*:** .* . *....*:::** * * :** * :**:** :** * :*:.**: :* .*: . :: : :.** .* **:* ****.**********:** ****.**:* **:: :*** ::**:: .***** :** .:*********** :** ********************* *****:*:**::*********** **:*:.:*****:******** ***.:*.********** ** .:**** *::***:*****:***:::* ***********.****.***.:*****.:*:****:*::*.* *:** * :**..: :* : .:.* *:** ", "identical_positions": 229, "similar_positions": 101, "identity": "58.12%" }, { "cls_id": "homologset.agr.MGI:2143537", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADJ8-1", "uniprot_id": "D4ADJ8_RAT", "id": "D4ADJ8-1", "name": "", "aln": "-MEGLVLLKALVTRLLFLLHSLVAVWRVTWVKEEHRYWLLALLNLLLVLETVLTLKFKRGRGYKWLSPAIFLYLINIMPSLWLLEMHHGNQYCSTQSETAAQNFSGRGD----INQTLSSHRATDGVGNILELARGFVDNLSMVCEPVWTLGLHQTLLLILIIGRWLLPIGGTITRDQLSELLLMFVGTAADILEFTTETLKENNVRNNPALVSGILVVWTWSMLQFPLDLAVQLKLVCPAS-VKARG--FLRVFLCQYSADLWAIGLSFFIQDGPFLVVRLVLMIYFKVINHMLVFFAVKNSLVMALHFYRLVALIMATRDFMQD------------------------------------------------------------------------------------------------HPESPKTEHSGPDQPSESGPS--EWEDTSPE--ALPLRISPVTSEESYPTTP---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UP23-1", "uniprot_id": "TMM26_MOUSE", "id": "Q3UP23-1", "name": "Transmembrane protein 26", "aln": "-MEGLVLLKALVTRLLFLLHSLVAVWRVTWVKEEHRYWLLALLNLLLVLETVLTLKFKRGRGYKWLSPAIFVYLVNIMPSLWLLEMHHGNQYCSTQSERMAQNFSRRGD----VNQTLSSHRATNGMGNILELARGFVDNLSMVCEPVWTLGLHQTLLLILIIGRWLLPIGGTITRDQLSELLLMFVGTAADILEFTTETLKENNVRTNPTLVSGILVVWTWSMLQFPLDLAVQLKLVCPAS-VKARG--FLRVFLCQYSADLWAIGLSFFIQDGPFLVVRLVLMIYFKVINHMLVFFAVKNSLVMALHFYRLVALIMATRDFMRD------------------------------------------------------------------------------------------------HPESPKPEHSGPDQPSESGPS--EWEDASPE--ALPLRTSPVTSEESYPTTP---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUK4-1", "uniprot_id": "TMM26_HUMAN", "id": "Q6ZUK4-1", "name": "Transmembrane protein 26", "aln": "-MEGLVFLNALATRLLFLLHSLVGVWRVTEVKKEPRYWLLALLNLLLFLETALTLKFKRGRGYKWFSPAIFLYLISIVPSLWLLELHHETQYCSIQAEGTSQNTSRKED----FNQTLTSNEQTSRADDLIETAKVFVNNLSTVCEKVWTLGLHQTFLLMLIIGRWLLPIGGGITRDQLSQLLLMFVGTAADILEFTSETLEEQNVRNSPALVYAILVIWTWSMLQFPLDLAVQN-VVCPVS-VTERG--FPSLFFCQYSADLWNIGISVFIQDGPFLVVRLILMTYFKVINQMLVFFAAKNFLVVVLQLYRLVVLALAVRASLRS------------------------------------------------------------------------------------------------QSEGLKGEHGCRAQTSESGPSQRDWQNESKEGLAIPLRGSPVTSDDSHHTP----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q715-1", "uniprot_id": "A0A8M1Q715_DANRE", "id": "A0A8M1Q715-1", "name": "", "aln": "-MILVKFVCAIITRSLFILVSLIGVWRVKTVKNDNMYWLLTILYLPLVVEMIITLKRRKGQDYKWFSPAILLFLISIIPSIWILELHHQENKAS---DPQCRKLDSWDN----VKSILPSNGTMG-----NATLKYLESMLTSVCANDWILALHQVLLILLILGKWLLPLGGGVTRDELSQLLLIFVGTAADILEFTSETLSDVKE-NNHQLVYIILAVWTWSMLQFPLHLAVVTSRPENTD-EPKGGDGCCNLILSRHSTDIWNIVESLFIQDGPFLVVRLIVMIYFDVFHQMLVFFAIKNFLVVVLNLYRLIVICQDFR----------------------------------------------------------------------------------------------------------------PKPPSSSSS--------------VPI------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBE7-1", "uniprot_id": "Q9VBE7_DROME", "id": "Q9VBE7-1", "name": "Transmembrane protein 26", "aln": "MAKIISTIKAILTRIIFSAHSLLAIWQVVALKSDIIYWALCGPLLLLLLEGIFTIMIKKTQEWRWFCPSVFLYLSSIVPAIWLLELDKVARRVGNMTSTNSTVYSPSNYSIPVGNTTIFITSTNSSGVPPVATLLGQAGVTLSVTPDTWTTLIEQFLMLILIVGRWLLPKG-DLTRDQLSQLLLVYIGTAADIIEFFDS-YKDDSIAKIGFLVFLTLGIWSWSLMQFTIVLSATRGRRPRGSGSHHKEEHTDCCQNCCCGIDVWGIVLNVILQDAPFLTFRLLIIFQYKIINYMNVFFTCKNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: ** :* **:.:*:* :*.: ** * * *.:* :*: :: : ::*:.*:::::* .*:*::*:**:.: . . . . . : : . . * * :.* ::::**:*:**** * :***:**:***:::******:** . .: . . ** * :*:**::**.: *:. . . . *:* * ..::**.***..**::: :.::: * ***: ** **: *::*** .: .*... ", "identical_positions": 83, "similar_positions": 101, "identity": "15.81%" }, { "cls_id": "homologset.agr.MGI:2143539", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28492-1", "uniprot_id": "GLSL_RAT", "id": "P28492-1", "name": "Glutaminase liver isoform, mitochondrial", "aln": "MRSMRALQNALSRAGSHGQRGGWGHPSRGPLLGGGVRYYFGEAAAQGRGTPHSHQPQHSDHD-ASNSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKELTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAAYSGDVSALRRFALSAVDMEQKDYDSRTALHVAAAEGHIDVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSY-----------MLSETQAEVAAETLSKENLESMV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571F8-1", "uniprot_id": "GLSL_MOUSE", "id": "Q571F8-1", "name": "Glutaminase liver isoform, mitochondrial", "aln": "MRSMRALQNALSRAGSHGRRGGWGHPSRGPLLGRGVRYYLGEAAAQGRGTPHSHQPQHSDHD-ASHSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKEPTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSQRGINFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSY-----------LLSETQAEAAAETLSKENLESMV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI32-1", "uniprot_id": "GLSL_HUMAN", "id": "Q9UI32-1", "name": "Glutaminase liver isoform, mitochondrial", "aln": "MRSMKALQKALSRAGSHCGRGGWGHPSRSPLLGGGVRHHLSEAAAQGRETPHSHQPQHQDHD-SSESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSEMHRVVQESSSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDVKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGTSFCQKLVSLFNFHNYDNLRHCARKLDPRREGAEIRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSY-----------TLSETQAEAAAEALSKENLESMV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZE4-1", "uniprot_id": "A0A8M9PZE4_DANRE", "id": "A0A8M9PZE4-1", "name": "glutaminase", "aln": "MHCVKTLRATRAGVLLIRNAGKWERVAGSLGRKHSPVRPLHTSASPGQHPRQQHAVNETDAATYSREKVVSGLEDLLFYTITQGEEKISVARFLTALKSTGLQTSDPRLRDCMRQIHHAVQDSVGTAMMDQELFRKCVGSNIVLLTQAFQRKFIIPDFEAFTSLINHLYCDAQTQQGGKVANYIPQLAKFSPDLWGVSLCTVDGQRHAVGDTNVPFCLQSCVKPLEYALAVHETGSEHVHRYVGKEPSGLKFNKLSLDEEEKPHNPMVNAGAIVISSLLKPGYNKAEKFDYMVDYLKRMAGREYVGFSNATFQSEKETGYRNYAIGYYLKEKKCFPNGADMTAALDFYFQLCSIEVTCESGSVMAATLANGGICPITGERVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVSGAVLLVVPNIMGVMCWSPALDRVGNSIRGIHFCQELVSLFNFHNYDNLRHFAKKLDPRRQTGHERNKSVVDLMFAAYSGDVSALRRIALSAVNMELTDYDSRTALHVASAEGHLEAVKFLTDTCKVNPYVKDRWGNTPLDDAMQFGHNTVAKVLQEYQSIYTHTLLPEVLSADTCPDSSIDADELKSMETLESLI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB40E7Z6-1", "uniprot_id": "A0AB40E7Z6_DANRE", "id": "A0AB40E7Z6-1", "name": "glutaminase", "aln": "MFSLRTLRLPNIGLIGLLSKDAVKSSVRSPNVVRGPLSLFSRVNVISKFTEAASADQPKSKANMTNKDLFSGLEDMLFYTITEGAEKVPVSHFTAALKSTGLLTSDPRLRDCMEKIRRAVRDSTGEVMMDRELFKKCASGNIVLLSLAFRRKFIIPEFEAFVDIINHIYYTSKLQQDGQVAKYIPHLTKFSPDLWGVSLCTVDGQRHSVGDTKVPFCLQSCVKPLEYAIAVHEHGTEHVHQYVGKEPSGFKFNKLSLDEEDKPHNPMVNAGAIVISSLIK-GVNKAEKFDYVMDFVKKMTGSEYVGFSNATFQSEKETGDRNYAIGYYLKEKKCFPDGVEMIDALDFYFQLCAIEVTCESGSVMAATLANGGICPITGERVLSTEAVRNTLSLMHSCGMYDYSGQFAFHVGLPAKSGVSGAVLLVVPNVMGVMCWSPPVDKVGNSVRGIRFCQELVSLFNFHNYDNLRHFLKKQDPRRQSGDDRNKSVVNLMFAAHSGDVSALRRFALSSMNMELRDYDSRTPLHVAAAEGHVDVVLFLIQACKVNPFVKDRWGNIPRDDAMQFGQKDVVKILEEYEQTY---------SPQTSQTDTEDLSQPSKCSSLGCNLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:::*: . . . . : .: . : . :.. :.. * *:*****::* *::.: :* :***:*** ******:*** :::: *::* . ::*::**:**...*****: **::**:**:** *.. ::::: : .*:** ***:*:* .****************:**.*::*********** **::: *:::**::*******:::*****:** ************:***:* . *******::::::::*:* *::************** ****************.*.:* ***:*****::************************* ***:*****************:**************.****:******:**:** **.:*::*** ** ***:*************** :* ****: .. ***:**:*:***:*********:***:::** ******.****:****::.* ** ::*****:.****** * ***:**.: *.*:*::*.. * . .: : . ..* . : ", "identical_positions": 338, "similar_positions": 151, "identity": "54.96%" }, { "cls_id": "homologset.agr.MGI:2143575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCV9-1", "uniprot_id": "MF4B1_MOUSE", "id": "Q8VCV9-1", "name": "Sodium-dependent glucose transporter 1A", "aln": "----------------------------------------------------------------------------------------------------MYAAFLGLGMSVAILGPTFQDLAENVNRNISSLSLIFVGRATGFLSGTMIGGVLFDHINQFFLLGASMVATAAGLYLIPFCKTAVLLIITMSV-FGASVGVVDTGANVLILDLWGDKGAPQMQALHFSFALGAFLAPLLAKLAWG-TAPAQNHTESDLDTLMLNRSSNGTSDSVFAVPDDMNLLWAYASIGTFILVVSVFLFGLFCKKHSRQKKPRASAEGARRAKYHRALLCLLFLFFFFYVGAEITYGSYIFSFATTHVGMEESEAAGLNSIFWGTFAACRG-----LAIFFATFLQPGTMIVLSNIGSLVSCFFLVLFDKS----PLCLWIATSVYGASMAATFPSG--ISWIEQYTTLTGKSAAFFVIGSALGDMAIPAVIGILQG--HYPDLPVVLYTCLGSAIFTAILFPVMYKLATLP-----LKR--------EDQKALPTSSRL------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L004-1", "uniprot_id": "A0ABK0L004_RAT", "id": "A0ABK0L004-1", "name": "", "aln": "MESELSQWPAAARVEVQPLIRTFPGGRQEGPGSLGEPERGAPEGASVLVALLSRQAGAGPEDPERRARGRGTEAPPCADPGRERASRGGLPAEWPGQERAALVLHRGPGMSVAILGPTFQDLAENVNRNISNLSLIFVGRATGFLCGTTIGGILFDHMNQFFLLGASMVATTVTLYLIPFCKTAVLLIITMSA-FGASVGVVDTGANVLILALWGDKGAPHMQALHFSFALGAFLAPLLAKLAWGTTASAQNHTESDFDPLMLNRTSEAATDSVFAVPDDMNLLWAYASIGTYVLVVSVFLFALFCEKRSKQKKSSASAQEVRRAKYHRALLCLLFLFFFFYVGAEITYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRG-----LAIFFATCLRPGTMIVVSNIGSLASSFFLVLFDKS----PLCLWIATSVYGASMATTFPSG--ISWIEQYTTLTGKSAAFFVIGAALGEMAIPAVIGILQG--HYPDLPVVLYTCLCSAIFTAVLFPVMYKLATLP-----LERQRKGRRKSEDQKALPTSSRL------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LLD5-1", "uniprot_id": "A0ABK0LLD5_RAT", "id": "A0ABK0LLD5-1", "name": "", "aln": "-MDTVLILEGYFQLRRITLMR--------FPTSLNFHCRLGAVGG---------------------DTGGGTGAFTCSHPNHSCKLQMIKLSNFTLPLPGGLTKFCQLGLSTALLGPTFQDLARNVNRNISDLSIIFVGRASGFLCGTMVGGVLLDYMNQFLLLGVSMSATAVGFYLIPLCKKVFLLIIMMSV-FGASIGVVDTGANVLILDLWGDKGAPHMQALHFSFALGAFLAPLLAKLAWGTTASAQNHTESDFDPLMLNRTSEAATDSVFAVPDDMNLLWAYASIGTYVLVVSVFLFALFCKKRSRQKKSSASAQGARRAKYHRALLCLLFLFFFFYVGAEITYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRG-----LAIFFATCLQPGTMIVVSNIGSLASSFFLVLFDKN----PLCLWIATSVYGASMATTFPSG--ISWIEQYTTLTGKSTAFFVIGAALGEMAIPAVIGILQG--HYPDLPVVLYTCLCSALFTAVLFPVMYKLATLP-----LERQRKGRRKSEDQKALSSINGNMQRNGMECILK-------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TF39-1", "uniprot_id": "S60A2_HUMAN", "id": "Q5TF39-1", "name": "Solute carrier family 60 member 2", "aln": "---------------------------------------------------------------------------------------------------MLCASFLGLGLSVAIVGPTFQDLATNVNRNISSLSFIFVGRALGYLSGSVIGGFLVDVMNYFLLLGISMSATTVGLYLVPFCKTAILLTVMMSI-FGVSIGILDTGGNVLILAIWGDKGAPHMQALHFSFALGAFLAPLLAKLALGPTASAENHTESDFHP-ALNQSSDADSEALFGVPNDKNLLWAYAVIGTYMFLVSVIFFCLFLKNSSKQEKARASAETFRRAKYHNALLCLLFLFFFFYVGAEVTYGSYVFSFATTHAGMKESEAAGLNSIFWGTFAACRG-----LAIFFATCLQPGTMIVLSNIGSLTSSLFLVLFDKN----PICLWIATSVYGASMATTFPSG--VSWIEQYTTIHGKSAAFFVIGASLGEMAIPAVIGILQG--KYPDLPVVLYTSLGASIATGILFPVLYKLATSP-----LDRQRKEDRKSEDQKALLSSSGLNEYEEENEEEDAEKWNEMDFEMIETNDTMRHSIIETSRSSLTEPTAEVYNQYPSNALVFESSPFNTGSAHVKHLPETRTKGTNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QN56-1", "uniprot_id": "S60A2_DANRE", "id": "A4QN56-1", "name": "Solute carrier family 60 member 1", "aln": "-MSPAEAAPRKKHVRFARMEGDVDHDDQEENTLFDKQKDVKEGLKSVLKG-------------GKGILSQGSGQVDVVRPGRSKTGTCWR----WLVSLALCASFLGLGMAISVLGPTFEDLAINVNKNISNLSYIFVGRASGYIGGSLLGGILFDFVNPHLLLGFALLTTAFGMSGTPFCKKAWVLTVLMSS-VGVSMGVLDTGGNVLILNTWGEQAGPHMQALHFSFAAGAFASPIIAKLLFGHHNSSTNTSLMSGHASKTIDAVLPFSHPKGTSTIDLPWMWAYIVIGAFVLLVSLLFFSLYFCISTNSNRTKTASGKQQFSKHHNTLIILLSMFFFFYVGSEVAYGSFIFTYGKDYVHMEETEAAGLNSLFWGAFAAGRG-----LAIFFAACLHPGTLILLSLVGTTVSSLLLCLFSQN----YPMLWACTALYGISMSTTFPSG--ISWVEQYTTVTGRSAAIFVVGAALGEMVLPALLGFLLG--HVQNYPLLMYLTLCTATFTSILFPVLYKLASPEGNVTLRKSSGKCTIKDADDSEYRQALLENMEEQEENESEADLCNDADFEVIEMDDASLLSSPKSSPPADVAASVPDVHLVASPLSEPNMLSFSTDSPRSKL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08280-1", "uniprot_id": "BSC6_YEAST", "id": "Q08280-1", "name": "Bypass of stop codon protein 6", "aln": "-MDASSVPPKVDDYGMYTTEISHHNPIELKNLLSSSDSRRNSQDEDSLPN----------------NTNLIKEIDWQGEKVKTYPLNYQTVPLVKLQVIACLIMFVVFGMNDQTVGALLPTLIEYYHISRVDVSNVFIVQLCGYVMASLSKERLNKHFGMRGGMLLAAGLCIVFLIILATAPSSFYVCMFCGLPLGLGIGILDSTGNVLMGSLLVHKN-ELMGIMHGLYGAAAMVTPPLVSYFVEWGHWSLFFLIPLFFS--IIGMIVIFPAFKFETASKYDYLCSVENKESNNDVEEAGDNSLMESTKASPG---------FFELLRNPAIFLYSLYLFLYLGAEITTGSWFFSYLLETKSSNKVAMSYIAASFWTGLTVGRLCLGFVTERFFENEYKASKAYAFLTLSSYTLFVLVGLINSSSVFYFVVLFFVVFCCGTFIGPLFPNASIVALQVLPKRLHVSGVGVAVAVGGCGGAAIPYLAGVIAHTVGIQYIPLLCWIMVALFTLEWTLYPKFIKGHEEYF---------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: :*. : * : . .:* :*: : *:: .: * . .. : : : . . . : : . .* .:*::*: .***: .: * :* :. .*: :* :.. : . . . . : : : : . * : :.. : * :::*:*:*:*:: **:.*:: :: : : : ** ::. * ** :... . :.: . .:: *:... *: . * :.. **.. :: . : .... * .. * .:* : *.: *:: : : *:* : * ", "identical_positions": 44, "similar_positions": 126, "identity": "6.91%" }, { "cls_id": "homologset.agr.MGI:2143585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WF7-1", "uniprot_id": "FIG4_MOUSE", "id": "Q91WF7-1", "name": "Polyphosphoinositide phosphatase", "aln": "------MPTAAAPIISS------------VQKLVLYETRARYFLVGSNHAETKYRVLKIDRTEPK-DLVVIDDRHVYTQQEVRELLGRLDLGNRTKMSQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKIEDTSMIYIPND-SVRISHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSETSKACQESFDIFEDEGLITQGGSGVFGISSEPYMKYVWNGELLDIIKNTVHR--DWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFT--------AGSYSSYVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHVAALHFDQMLQRFG-SPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGHVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGK--PHLWELPTDFYLHHKNTMSLLPPRRSYTYWWTPEVVKHLPLPYDEVICAANLKKLMVKKFHRWEEEIDIHN----EFFRPYELSSFDDTFCLAMTSSARDFMPK-TVGIDPSPFTVRKPDETGKSVLGNKNTREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREDEGSISQRSTPVKMTDTGDSAKATENVVQP-MKEVYGVSLSSSLSEEDHSIYARFVQLGQSQHKQDRGNQQLCSRCSDGVIKLT------PISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDTAMYREYIRNRYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92562-1", "uniprot_id": "FIG4_HUMAN", "id": "Q92562-1", "name": "Polyphosphoinositide phosphatase", "aln": "------MPTAAAPIISS------------VQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPK-DLVIIDDRHVYTQQEVRELLGRLDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIYIPND-SVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKSTVHR--DWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFT--------AGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAALHFDQMFQRFG-SPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGK--PHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYDEVICAVNLKKLIVKKFHKYEEEIDIHN----EFFRPYELSSFDDTFCLAMTSSARDFMPK-TVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQP-MKELYGINLSDGLSEEDFSIYSRFVQLGQSQHKQDKNSQQPCSRCSDGVIKLT------PISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDSSMYREYIRNRYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR06-1", "uniprot_id": "Q9VR06_DROME", "id": "Q9VR06-1", "name": "", "aln": "-MNNDNPNIVFNPLISS------------IQKVVLYETRARLYLVGSNNRETRFRLLTIDRLAHN-RLSIEENANEFNSLEIRRFVASL-------------SGSPKVTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVNEVTSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGAKVDLDRDEPLPDWNTLTSNVDKAHERVD--YAFRSDSRKRFVWNAYLLQPMEGIMLK--DWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSDG---------------QRICAFTQMRGSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYG-APLIMLNLVKKRERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESIVQMTGMFFKAAGS------------EPG--------LQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHRIKTYRKTAPWGSQGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKPSLTKQGPPIWELQTDYDMH--NAFVPRADSKAITDWVRHKVRACLPYSCAD---SNKLVKELFRVHSSGLEMIDAYS----NYHQSFKWTDFSEHIAFEISQLALRYMP--TFRTNFSPFQR--------QIQTSRKARQNPSMTGQSSTGSMNSNSS---SSSEGDDSSSD--EELSASFAEKEANQTESTEPAAATLATGLPSMEEIYGCTINP-PSKQSMAVYKKYVQMGKLSSGGARPAQTAVAQRDQELAKIMRGITLRPLSDYGTDSYLSVRPPVVPRKSLTIYAEYCRTRSTFNAVPKLEEFDVLYQYVQKL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42837-1", "uniprot_id": "FIG4_YEAST", "id": "P42837-1", "name": "Polyphosphoinositide phosphatase", "aln": "MNNDAMEHTLGGGILTTSGSKQRKTSKFVMGKYTLYETKDRMYIVGSNKRETMFRILEIDLTVPRGELTVLEDNVFFTRNEIMNVLASLEEAT--------EDGLHKKITGYGLLGFIKFTCWYYLIMVTKYSQVAVIGGHGIYHIDGIDIIPITNNYKKPEKSSDEARLLNIFKDLDLTKTFYFSYTYDITNTLQTNILREKLKAVDR-CDITIPCG----------------------ITDYNEMFVWNNNLLSPIFACIDTVFDWFQCIIHGFIDQVNVSVLGKSIYITLIARRSHHFAGARFLKRGVNNKGHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTSFVQHRGSIPLYWTQDASNLTTKPPIRINVVDPFFSPAALHFDNLFQRYGGGTIQILNLIKTKEKTPRETKLLWEFEQCIDYLNEFLPTLKKLDYTSWDMSRASKQDGQGVIEFLEKYAVNTVTTTGIFHNGPDFAS-------------------TKIQEGICRSNCIDCLDRTNAAQFVIGKRALGCQLKSLGIIDNSYLEYDSDIVNILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMIESIKRFYSNSFVDAQRQDAINLFLGHYSWREGF--PSLWEMNTDFYLH--NAYSLNMPKRSYIHWWNDYNIKSVKELINEELIATGNDVTREKIIKNVRGYPGAFDNYWNEYYLPRSVTWIRDLFAYNMNSTRRYHNALSKQDKAMSPFTSRK-----QSWLNNKLKMITSSKSLEKAEGRVVETTDLDRDTSPKQE--LELYEHYLHIISDRSQKLEEKMNSFSYSKYPIFISHESSEIPPMRKVIGEPLVDIAEDFTDVYDDDDDGDDENDEMTTEALLIAPDHVS---------VDEKFYEKVLNVDDYKPALDDYSAVIHIKPDNLQLYRDLCFSKDIQLDFQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: : * .****: * ::****: ** :*:* ** . * : :: :. *: ..:. * .* : :.:*::**::* **::::** * ** * :* :.. :: : : . ..* * .:*:::** ..*****:**::.:** * : : :: :*** **. : : **: : *** .* : : *: : : *:**** :***:******.* :*.**********: * ::.* ***:* .*:** *.: .** * :: **: .:***:.:: ::* ..: :***:* :*: :* : *: .: ***:***. : : : :**:: :: . .*:: * * . * **:* : .. :* ** *:**:*******:*** :** **. ** **::... *::*:* * :: :*:.: ***::******:**: ::**** * .:. *:::::.*:***:* *:::*.:****** : * :**: **: :* *: :: * : : : : . .. ::. . . : : : :. :.. . . . *** . .: . :.: . :. .:* :: : :. . : : :. : :. : .: : :.:: . . : :. . . . .* : : : : : : ", "identical_positions": 199, "similar_positions": 254, "identity": "20.9%" }, { "cls_id": "homologset.agr.MGI:2143599", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZS21-1", "uniprot_id": "A0A8I5ZS21_RAT", "id": "A0A8I5ZS21-1", "name": "E3 ubiquitin ligase TRAF3IP2", "aln": "---------MNRSIPVEVDESEPFPSQLLNPIPESSPEEELEPPAPNTRNTAPSSLSV------------LQRPPLKLANHQ-PVSQQVTCLRAKVLEESEASFLRRHPDLGKDVSSCSSEASEPGSE--LGALSLEHRFTHMEKRDRWLGPQLSAASPDTGHDSDKSDPSLPMALADSSSSDQEMRPRPGSRPRPWPRHHRNRAAPDVPTIDTGYDSQPQDVLGIRQLEKPLPLTSSCYLQDLPGPLRSKEFP-QFELQRYPANAPMLPLDPSPQVPWSYQYCRPGGPYHHQAPYGHGYPPAAAYQQVIQPALPEQALLGARVRGLHPMQKVVLNDSSPQDQEERPAQRDFSFSRLPR--DRLCRPP--SNGAGAPEESLDRPAELRPHGPQALSPAAVPRPPSNPLARGTLKTSNLPEELRKVFITYSMDT---AMEVVKCVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGTGSQLDEDEHGLHTKYIHRMMQIEFINQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQSSRPPESEVSSPGLQCFWEWMLQVMAARTYGHKNSHHFSYSYELAGCFVSLDQSESCSINKVIILCKNVFVSVEVGLLIYTGTGSSRTSTKLLRYSIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N7N6-1", "uniprot_id": "CIKS_MOUSE", "id": "Q8N7N6-1", "name": "E3 ubiquitin ligase TRAF3IP2", "aln": "---------MNRSIPVEVDESEPFPSQLLKPIPEYSPEEELEPPAPNTRNMAPSSLSV------------LQCPPLKLANHQ-PVSQQVTCLRAKVLEEGEASFFRRHPELGKDISSCSSGASEPESE--LGALPPEHRFTLTEKRNRWLGSQLSAASPDTGHESDKSDPSLPNALADSFSGGQEMMPRP--RPRPGP--HRHRAAPDVPTIDTGYDSQPQDVLGIRQLERPLPLTSSCYLQDLPGPLRSRELPPQFELERYPMNAQLLPPHPSPQAPWNCQYYCPGGPYHHQVPHGHGYPPAAAYQQVLQPALPGQVLPGARARGPRPVQKVILNDSSPQDQEERPAQRDFSFPRLPR--DQLYRPP--SNGVEAPEESLDLPAELRPHGPQAPSLAAVPRPPSNPLARGTLRTSNLPEELRKVFITYSMDT---AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFISQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43734-1", "uniprot_id": "CIKS_HUMAN", "id": "O43734-1", "name": "E3 ubiquitin ligase TRAF3IP2", "aln": "MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPTMLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCSAVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSLGGSQEMVQRP------QP--HRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPLRSREFP-QFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSP-DHQVPYGHDYP-RAAYQQVIQPALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQP--PNRAGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT---AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GU74-1", "uniprot_id": "A0AC58GU74_DANRE", "id": "A0AC58GU74-1", "name": "E3 ubiquitin ligase TRAF3IP2", "aln": "---------------------------------------------------------------------------MKIQSRQLQASAHNLVAASRADSGSHAAAPARSAAASGSIDSGWNRAVSPGIR-----------------------SRSSRGSQSEGQLSHMAHSSDQYTSLNSPEENDETSSQE----------------------------FESDILLNHSTTVPQPTHN---VHQRTNAIFSHQHP---------------PPSLTHQTPFPSWVELRASPQSLPSALYHTLSDSGSFFPSRPHSLPGSCSP----------SLVSLEHPRSLHSFLHSGDFYHHQPPLPSYPDTYMRPPCCTQCRPAPQQQIYRPSGLTQYRQVDTHFSENAHAPLNSRPAANQSITHLPQEQRKVFVTYEADSEEHLKEIIKFVSLLRNNGFDTHIDVFEQQLNSISKIDCMERYLNEKDYLIIIIISLRYYETICSGNISVESDERTSNTVYIHKQLQSEFIQNGCRNYRFIPILFPGAKKCYVPAWLQNTHVYSWPADRDDILRRLMRVEKYRPPPVGSLPAIFSIPL----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: .:* .* : ::. . .. : * . . . * . . .* . .: * .* . *: *. :. * : :* .:* : .*:* :. * * . :: . .: *:: * * : :.*: ..* . * . .:: :** . . * *: . . . :..: . ** * : * .: ** :.: *: * : .:.* *. . .. ::**:* ****:**. *: *::* *.:* ***:* **:**:::..*. *. *****.:* :**: ** :* : : . .::.**: :* ***: :* ***.:*. *:****:***.*** :**:*********** ::.:** **:* *:* .** *.**:: ", "identical_positions": 119, "similar_positions": 136, "identity": "17.4%" }, { "cls_id": "homologset.agr.MGI:2143628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJT9-1", "uniprot_id": "D3ZJT9_RAT", "id": "D3ZJT9-1", "name": "", "aln": "-----------------MTESSSTTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMESVKKATATTTWMVPTAQDAPPSPLSSRPAFPPAYWTSPPGCPTVFSEKTGVPFRLKEQSKVDGLQFCENCCQYGNGEECLSGGNYCSQNCSRRARDKDQKEDRDGGEDNDEEDPKCSRKKKPKLSLKADSKED-EERDDEMENKQDGRILRGSQRARRKRRGDSAVLKQGLPPKGKK-TWCWASYLEEEKAVAVPTKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLRPPKGYKEEEFNWQSYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAADKKSPSIICVATVTDMVDNRFLVHFDNWDESYDYWCESNSPHIHPVGWCKEHRRTLITPPGYSHVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEAVDKRNPLFIRVATVADTDDHRIKVHFDGWSSCYDYWIDADSPDIHPVGWCSKTGHPLQAPLSPAELMEPSETGGCPTLGCRGVGHFKKSRYLGTQSGANCPYSEINLSKDRIFPDRLSGEITP-SSFSFPRSKRTDTNESSSSPETRDQHANNVKEDSEKKKENEVKTSAEAKVVREEPTPSVQQTQPPQQALKAPQAPQIQPAQQAPQAPQAQPTQQ--------QAQQAQQAPQAPQAQPAPQAPQTHPTQ--QQAQQAQPTQQ--QAQQAQPTQQQ-QAQQQAQRRSAVFLSFKPPIPCLPLRWEQQSKLLPTVAGIPASRVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLB7-1", "uniprot_id": "LMBL3_MOUSE", "id": "Q8BLB7-1", "name": "Lethal(3)malignant brain tumor-like protein 3", "aln": "-----------------MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMESVKKATATTTWMVPTAQDAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGVPFRLKEQSKADGLQFCENCCQYGNGDECLSGGKYCSQNCARHAKDKDQKDERDGGEDNDEEDPKCSRKKKPKLSLKADSKDDGEERDDEMENKQDGRILRGSQRARRKRRGDSAVLKQGLPPKGKK-TWCWASYLEEEKAVAVPTKLFKEHQSFPYNKNGFKVGMKLEGVDPDHQAMYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLRPPKGYKEEEFNWQSYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAADKKSPSVICVATVTDMVDNRFLVHFDNWDESYDYWCESNSPHIHPVGWCKEHRRTLITPPGYSHVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEAVDKRNPLFIRVATVADTDDHRIKVHFDGWSSCYDYWIDADSPDIHPVGWCSKTGHPLQAPLSPAELMEPSETGGCPTLGCRGVGHFKKSRYLGTQSGANCPYSEINLSKERIFPDRLSGDTSPPTTPSFPRSKRMDTRESSSSPETREKHANNFKEDSEKKKENEVKTSAEAKVVREEPTPSVQQSQPPQQVQQVQHAQPPQQAQKAPQAQQAQQAQQAQQAPQAPQTPQPQQAPQVQQAQQAPQAQQAQQPQQAQQPQQAPPVQQPQQVQQAQPTQQQAQTQQQAQRRSAVFLSFKPPIPCLPLRWEQQSKLLPTVAGIPASRVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JM7-1", "uniprot_id": "LMBL3_HUMAN", "id": "Q96JM7-1", "name": "Lethal(3)malignant brain tumor-like protein 3", "aln": "-----------------MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATATTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKK-AWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPP-ASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREEPT------------------------------------------------------------------------------------------------------VQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I2A9-1", "uniprot_id": "A0AC58I2A9_DANRE", "id": "A0AC58I2A9-1", "name": "", "aln": "MNGRRLLDQSQADGVRVMASSGASAAAPEFDVYGAMDWKDGVGTLPGSELKFRVNEFGVLEVITEEMEEERGKKAHATTTWSVPTAQEALSEG-------------------SVLKQDS--PWGQRG-------LVCVRCNRKGSAVDFLPDGLHCSERCLQQEQEELKTE--GSRMNGELLSRKRTRLERSAEDMDS-SMDIPEEEDEDYEEKESRRPARGATRGRKKRRGDAALLRYTVPYGGKKKAWCWASYLEQERAIAAPSKLFKEYQCFPQCKNGFRVGMRLEGIDPEHPSMYCVLTIAEVSGHRIRLHFDHFSDCYDFWVNSNSPDIHPVGWCEKTGHKLHPPKGMKDEEFSWSSYIKLNKIQTAPKALFHNQNMTVTPSGFRVGMKLEAVCRKDPTFICVATVTDMVDSRFLVHFDNWEESYDYWCDATSPYIHPVGWCQENGRTLSTPPGYPDANNFSWEKYLAETSSLPAPARAFKVKPPHGFQVNMKLEVVDKRNPVLIRVATVADTDDHRLWIHFDGWTDEYDYWIDADSPDVHPAGWCAKTGHPLQPPITPQDMFEASEQAGCPTAGCRGVGHIKGARYSGHHSAVGCPYSDINLNKDSVLPDRLSAETPG-AGVGRPRRAEANQEISADANDKPVTCVPLLPDKANTGVETPVKKPAGTETKRRVGRPCKVR------------------------------------------------------------------------KVEVLPQEEEVESEVSSVTETKELTLQQALHQS-VFMPCSSPSPSMPHCWDQHSKLLPTVAGITASKVASWSIDEVIQFIQGLPGCKEQVRTFRDEQIDGEAFLLLTQVDLVKILSIKLGPALKIYNSILMFKTTENSACNEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.*.::::. ****:..*************:*********.*****:* * * *** ***** *****:* .. :*:.:.: *: : .* .* : *. : *..* :**:.* :: ::: :.: . :.: . * :* ::. .:.: : : **.*:: *:*:. * **: *.*:*****:*:*: :* *** :********:*:*:*.*:*****:*.** ****:***:***:**:* ::*****:***.*:**:**** :*********::: ***************:**** *:***.*.:*:* * *:***:**.***:** ************. :*.*:.***********.*********:*******::.**:*******:*: *** *****...::***:*** **.****************** :****.******::*************: :*****.. ***********:**.***:*******.*::* :::*.** .**.* **:*:**:* :*: * :*...****:***.*: ::*****.: . : . ** . : . *:.: : . . :. : *. ::.. :. *. *** ::* **:. ..* *.:* *:*:**********.**:*:.** *** :***.****:*: :.*:***********:**.*:***:**********:*******::*:.: ***", "identical_positions": 425, "similar_positions": 213, "identity": "47.17%" }, { "cls_id": "homologset.agr.MGI:2143652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQR3-1", "uniprot_id": "A0A8I6AQR3_RAT", "id": "A0A8I6AQR3-1", "name": "", "aln": "MGAGAEGAGRPRVGRARRRARGCWDGCARRATGGRGRGPGGASARARRNPRRGRRRELRRLRRGRVASGATSAARGRRRRRRRLHLLERRVFRLLSLRRASGSRSRPWPRQGLCCPGRFCCPRCHRSLRRAAAPGPDPAVIMNQADKNQ-EIPSYLSDEPPEGSMKDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVT---TVPSMGIGLVKGGVSAVAGGVTAVGSAVVNKVPLSG-KKKDKSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAM7-1", "uniprot_id": "TM263_MOUSE", "id": "Q9DAM7-1", "name": "Transmembrane protein 263", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MNQADKNQ-EIPSYLSDEPPEGSMKDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVT---TVPSMGIGLVKGGVSAVAGGVTAVGSAVVNKVPLSG-KKKDKSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUH6-1", "uniprot_id": "TM263_HUMAN", "id": "Q8WUH6-1", "name": "Transmembrane protein 263", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MNQTDKNQQEIPSYLNDEPPEGSMKDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVT---TVPSMGIGLVKGGVSAVAGGVTAVGSAVVNKVPLTG-KKKDKSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T352-1", "uniprot_id": "TM263_DANRE", "id": "Q7T352-1", "name": "Transmembrane protein 263", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MSETNQQRDDLPAYLNDEPPADANKDHPQPQPGMFSRVAGGLFSVTKGAVGATVGGVAWVGGKSFDLTKTAVTSVASVPAMGVGLVKGGVSAVAGGVTAVGSAVVSKVPIGGGKKKDKSD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:::::: ::*:**.**** .: ***** ****:***:**:***********:*****:****:::****** :**:**:**********************.***: * *******", "identical_positions": 85, "similar_positions": 26, "identity": "32.57%" }, { "cls_id": "homologset.agr.MGI:2143657", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TPD7-1", "uniprot_id": "LR75B_MOUSE", "id": "Q7TPD7-1", "name": "Leucine-rich repeat-containing protein 75B", "aln": "MGARLG------------RRAR----ADAPAAPS---------------------AGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILHRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRKH-----HRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDTRGVELVVLDLSFTELSDELLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDTAKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEP-GGGMAETTAAVSTWGSAATEAGPEPQG----------------CCAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M1Z9-1", "uniprot_id": "A0ABK0M1Z9_RAT", "id": "A0ABK0M1Z9-1", "name": "", "aln": "MGARLG------------RRAR----ADAPAAPS---------------------AGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILYRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRKP-----HRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDSRGVELVVLDLSFTELSDDLLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDATKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEP-GGGMAETTAAVSTWGSAATEAGPEPQG----------------CCAR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2VPJ9-1", "uniprot_id": "LR75B_HUMAN", "id": "Q2VPJ9-1", "name": "Leucine-rich repeat-containing protein 75B", "aln": "MGARLG------------RRAGPEAGSEAGAAAG---------------------CGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLERTLLPDILYRDVAFLNPVDPISHDLLVNLARDLQCPKKDYELWKSSDKICRQLIYHLTPHSKQQQGSSLRQRKTQSCLKSSLQKTLLAGETVDLSGIPLSTQDVQHITRYLSSHGAVLAVLDLSFTGLSDELLHLLLPSLWALPRLTQLLLNGNRLTRATARKLTDAIKDTTKFPALAWVDLGNNVDVASLPQPLLVGLRRRLSQRTSLPTIYEGLDLEP-EGSAAGATTPASTWDSTAAGLGPEPQA----------------CCAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXP5-1", "uniprot_id": "E7EXP5_DANRE", "id": "E7EXP5-1", "name": "", "aln": "MGSKLTRQSSLDSQASFFRRGRQDHEERRTGGRG-DFLFSSLMLRSDKLPGVLRRSSPCPYVRRVAWVREIQTLLKEQKLEQAIDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLNLARDLQCPKREADALKSSEKICRQLIYHLTPHSKWSR-QNVPRRKTQACLKTTLKKKLAN-DTVDLSGIPLSGRDLHRVAYYLQNNGSSVTAVDISFTELHDESLRLLLPYLGVLPKLSTLAINGNRLTVAILKDLIEVVKDPQKFPCLAWVDLGNNVDIFTVPQPLLVALRRRFGMRSSLPTIYEYSEGQGSSYCLETSVEEISVFEEEEEDEEDELEDHLVLEAWSVEEKNTLHFCER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QJF5-1", "uniprot_id": "F1QJF5_DANRE", "id": "F1QJF5-1", "name": "", "aln": "MGSRLSRQNSLDNEN-FSRRRRKHLDSTGESDRGGDFLFTSLMLRSDKLPGMLRRSNHSPYVRRVAWIREMQKLLRERKIEEATDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLSLARDMQCPKKDLETLKSSDKICRQLIYHLTPHSKWLR-KSMTRRKAQACLKTTLQKKLCS-DSVDLSGIPLSTRDIRHVAYYLQTSGGAVISVDLSFTELRDEGLRLLLPFLGALPKLTTLALNGNRLTLGILKDLSEAFKESKRFSCLAWIDLGNNVDIFTMPQPLLVALRRRCSLKSSLPTIYEYTEGQPYCYRMESSIEEPSHYEEEEDEDYDEDLEPWSIGEQKSSGSFTLHHCER", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::* ** . . .. .** *** *:**:*. *:*:: *.* ::*:***:***** . * ***:::.:*** ******:**:.****:****:: : ***:*************** :**:*:.**::*:*.* ::********* :*::::: **.. * : :*:*** * *: *:**** * .**:*: * :****** . :.* :..*:. :*. ***:*******: ::******.**** . ::******* : : : * : . * * *", "identical_positions": 145, "similar_positions": 82, "identity": "39.73%" }, { "cls_id": "homologset.agr.MGI:2143670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R205-1", "uniprot_id": "ZC3HA_MOUSE", "id": "Q8R205-1", "name": "Zinc finger CCCH domain-containing protein 10", "aln": "MPDRDSYANGTGSSGGGPGGGGSEEASGAGTGSGGATSDAICRDFLRNVCKRGKRCRYRHPDMSEVSNLGVSKNEFIFCHDFQNKECSRPNCRFIHGSKEDEDGYKKTGELPPRLRQKVAAGLGLSPADLPNGKEEVPICRDFLKGDCQRGAKCKFRHLQRDFEFDARGGGGTGGGGSTGSAPPGRRHDLYDIYDLPERGFEDHEPGPKRRRGGCCPPDGPHFESYECNLAPLRGVECRLLEEENALLRKRVEELKKQVSNLLATNEVLLEQNAQFRNQAKVMTLSSTAPATEQTLAPTVGTVATFNHGIAQTHTTLSSQALQPRPVSQQELVAPTGAPAAPPTNAAPPAAPPPPPPHLNPEITPLSAALAQTIAQGMAPPPVSMAPVAVSVAPVAPVAVSMAQPLAGITMSHTTTPMVTYPIASQSMRITAMPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLM7-1", "uniprot_id": "D3ZLM7_RAT", "id": "D3ZLM7-1", "name": "Zinc finger CCCH domain-containing protein 10", "aln": "MPDRDSYANGTGSSGAGPGGGSSEEASGAGTGSGGATSDAICRDFLRNVCKRGKRCRYRHPDMSEVSNLGVSKNEFIFCHDFQNKECSRPNCRFIHGSKEDEDGYKKTGELPPRLRQKVAAGLGLSPADLPNGKEEVPICRDFLKGDCQRGTKCKFRHLQRDFEFEARGGGGTGGGGSTGSAPPGRRHDLYDIYDLPERGFEDHEPGPKRRRGGCCPPDGPHFESYECNLAPLRGVECRLLEEENALLRKRVEELKKQVSNLLATNEVLLEQNAQFRNQAKVMTLSSTAPATEQTLAPTVGTVATFNHGIAQTHTTLSSQALQPRPVSQQELVAPAGAPAAPPTNAAPPAAPPPPPPHLNPEITPLSAALAQTIAQGMAPPPVSMAPVAVSVAPVAPVAVSMAQPLAGITMSHTTTPMVTYPIASQSMRITAMPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96K80-1", "uniprot_id": "ZC3HA_HUMAN", "id": "Q96K80-1", "name": "Zinc finger CCCH domain-containing protein 10", "aln": "MPDRDSYANGTGSSGGGPGGGGSEEASGAGVGSGGASSDAICRDFLRNVCKRGKRCRYRHPDMSEVSNLGVSKNEFIFCHDFQNKECSRPNCRFIHGSKEDEDGYKKTGELPPRLRQKVAAGLGLSPADLPNGKEEVPICRDFLKGDCQRGAKCKFRHLQRDFEFDARGGGGTGGG-STGSVLPGRRHDLYDIYDLPDRGFEDHEPGPKRRRGGCCPPDGPHFESYEYSLAPPRGVECRLLEEENAMLRKRVEELKKQVSNLLATNEVLLEQNAQFRNQAKVITLSSTAPATEQTLAPTVGTVATFNHGIAQTHTTLSSQALQPRPVSQQELVAPAGAPAAPPTNAAPPAAPPPPPPHLTPEITPLSAALAQTIAQGMAPPPVSMAPVAVSVAPVAPVAVSMAQPLAGITMSHTTTPMVTYPIASQSMRITAMPH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************.*****.********.*****:******************************************************************************************************************:*************:********** ****. **************:***************************** .*** *************:***********************************:****************************************************:***********************.***************************************************************************", "identical_positions": 418, "similar_positions": 13, "identity": "96.09%" }, { "cls_id": "homologset.agr.MGI:2143676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BG89-1", "uniprot_id": "ZN365_MOUSE", "id": "Q8BG89-1", "name": "Protein ZNF365", "aln": "MQQTTFEESRYHWQDSLENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLLPSLKDTELLRSSELPKQGKVLRGHAKVTKQKSSYVNLYSISHGHSKDTKPFEMVAERPVSYVQTYTAVDIRADSLDAPCASPGLPTQDTKAAFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFAQLTQKKQEVQRRERALNKQVDVAVEMIAVLKQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFSCDTSEHMLTDIPSNRKPRCLSRGHQHSVCNHPEMRAHFHLKGRSYLKKAKDERAGMQPAKAIHEPAESPREFFRPAKKGEHLGLSRKGNFRPKMAKKKPTAIVNII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQS2-1", "uniprot_id": "ZN365_RAT", "id": "Q5PQS2-1", "name": "Protein ZNF365", "aln": "MQQTTFEESRYRWQDSLENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLLPSLKDTDLLRSSELPKQGKLLRGHAKVTKQKPSYVNLYSISHGHSKDPKPFEMVAERPVSYVQTYTAVDIRADSLDAPRSSSGLPTQDTKAAFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALHKQVDVAVEMIAVLKQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFSHDTSEHMLTDISSSRKSRCLSRGHQHSVCNHPELKAHFHLKGRSYLKKAKDERAGMQPAKAIHEQAESPREFFRPAKKGEHLGLSRKGNFRPKMAKKKPTAIVNII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70YC5-1", "uniprot_id": "ZN365_HUMAN", "id": "Q70YC5-1", "name": "Protein ZNF365", "aln": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQS-SGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.:****** **:*:********:**************************************:******:*: **** * **: .:*.***.********** **** ****:**************:*::*****.. :..****.****:*********************************************.****************::************:******************************************************************* * * *:****.*.**.:****** *******:::**** ***.:******:**.********* ***.*:: **.**** **:.****:****************", "identical_positions": 341, "similar_positions": 47, "identity": "83.58%" }, { "cls_id": "homologset.agr.MGI:2143691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGP0-1", "uniprot_id": "A0A8I6AGP0_RAT", "id": "A0A8I6AGP0-1", "name": "", "aln": "MFRGHFLLQKKDLISDDRLSSAEEKRDPEKGRMNKRYLQKATQGKLLIIIFIVTLWGKAVSSANHHKAH--HVRTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRVTH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPG7-1", "uniprot_id": "TAFA2_MOUSE", "id": "Q7TPG7-1", "name": "Chemokine-like protein TAFA-2", "aln": "--------------------------------MNKRYLQKATQGKLLIIIFIVTLWGKAVSSANHHKAH--HVRTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRVTH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3H0-1", "uniprot_id": "TAFA2_HUMAN", "id": "Q8N3H0-1", "name": "Chemokine-like protein TAFA-2", "aln": "--------------------------------MSKRYLQKATKGKLLIIIFIVTLWGKVVSSANHHKAH--HVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRVTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NL22-1", "uniprot_id": "A0A8M1NL22_DANRE", "id": "A0A8M1NL22-1", "name": "", "aln": "--------------------------------MQERALQRAFAWIVLVFLALVLFWG-HLSEASSHRSHIVHVKAGTCEVIAAHRCCNRNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVAQKWWCQMQPCVDGEECKVLPDLTGWSCSTGNKVKTTKVTR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:* **:* :*::: :* :** :*.*. *::* **::*****:* *****:*********************************** *****:****::********* .*****:*******:**:", "identical_positions": 93, "similar_positions": 25, "identity": "56.36%" }, { "cls_id": "homologset.agr.MGI:2143698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3ZK22-1", "uniprot_id": "VEZA_MOUSE", "id": "Q3ZK22-1", "name": "Vezatin", "aln": "MTPEFDEEVVFENSPLYQYLQDLGHTDFEICSSSSPKPEKCLTTEGPQPPPTRVLQRQGILLKLTETIKSWTFSSQHSKKDDLLHKLDTGFRLDSLHTILQQEVLLQEDVELLELLDASILSAGQPQQ-ESGHLPTLCSLATPNTWDVSLLFAFISLLIMFPTCWIVSSWLVWGIILFLYLIIRVLKLWRTAKLQMTLKKYRVRLEDMAANSRAFTNLVRKSLRLIQETEVISRGFTL----VSAACSFNKAAQHPGQHLIGLRKAVYRTVRANFQAARLATLYMLKNYPLNSESDNVTNYICVVPFKELGLGLSEDQISEEEARNLTDGFSLPALKVLFQLWVAQSSEFFRRLALLLSTANSPSGPLLTAALLPHHILCDVTQGLPHAHSACLDELKRSYEFFRYFETQHQSVPQRLSKTPQKSRELSNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELLSEAYPILEQKLKLIEPHVQASNSCWEEAISQVDKLLRRNTDKKGKPGVACENPHCTAEPLVRPALHIEDRDPIPEEQELEAYVDDIDIESEFRKDDFYHLSQEDRERQKREQEESRRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLTSLSPVDPVESVSNSEPPMNSDTEKVNSNATEEETSKPCAGDKEDSRTEYVCDSPTEGPSKDTSADTGLLLPGAEETMCHQHESEAKSPQAAAAGATAPPTPRDTLQLSIKQRLARLQLPPEFTFSAGLAAEVAARSLSFTTMQEQTFGDEEEE---QLVEGGENEVEEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI52-1", "uniprot_id": "VEZA_RAT", "id": "Q5XI52-1", "name": "Vezatin", "aln": "MTPEFDEEVVFENSPLYQYLQDLGHTDFEICSSLSPKTETCLTTEEPQTPPTRVLQKQGILLKLTETIKSWTLSSQYSKKDDLLHKLDTGFRLDALDAILQQEVLLQEDVELIELLDPSILSAGHPQQ-ENGHLPTLCSLATPNIWDVSMLFAFISLLIMLPTWWIVSSWLVWGIILFLYLIIRVLKFWRTAKLQMTLKKYRVRLEDMAANSRAFTNLVRKSLRLIQETEVISRGFTLLLDRVSAACSFNKAAQHPSQHLIGLRKAVYRTVRANFQAARLATLYMLKNYPLNSESDNVTNYICVVPFKELGLGLSEDQISEEEARNLTDGFSLPALKVLFQLWVAQSSEFFRRLALLLSTANSPSGPLLTAALLPHRILSDVTQGLPHAHTACLDELKRSYEFFRYFETQHQSVPQRLPKTQPKWRELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELLSEAYPVLEQRLKLIEPHVQASNSCWEEAISQVDRLLRRNTDQKGKPGVACENPHCTAAPLLRPTLHIEDRDPIPEEQELEAYVDGIDIESEFRKDSLYHVSQEDRERQKREQEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVEPVESVSNSETPMNSDTEQAHSEATEEETSKPCASDKEDTRTEYMCDGPPKGQSKDTSGDQGHLLQG-----AHQCESEAKPPQAAAAGATAPPTPRDSPRLSIKQRLARLQLSPEYTFTAGLAAEVAARSLSFTTMQEQTFGDEEDEDKEQLVEGGERELEEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBM0-1", "uniprot_id": "VEZA_HUMAN", "id": "Q9HBM0-1", "name": "Vezatin", "aln": "MTPEFDEEVVFENSPLYQYLQDLGHTDFEICSSLSPKTEKC-TTEGQQKPPTRVLPKQGILLKVAETIKSWIFFSQCNKKDDLLHKLDIGFRLDSLHTILQQEVLLQEDVELIELLDPSILSAGQSQQQENGHLPTLCSLATPNIWDLSMLFAFISLLVMLPTWWIVSSWLVWGVILFVYLVIRALRLWRTAKLQVTLKKYSVHLEDMATNSRAFTNLVRKALRLIQETEVISRGFTL----VSAACPFNKAGQHPSQHLIGLRKAVYRTLRANFQAARLATLYMLKNYPLNSESDNVTNYICVVPFKELGLGLSEEQISEEEAHNFTDGFSLPALKVLFQLWVAQSSEFFRRLALLLSTANSPPGPLLTPALLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKSRELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLKLIQPHVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNE-VFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQRLARLQLSPDFTFTAGLAAEVAARSLSFTTMQEQTFGGEEEE---QIIEENKNEIEEK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************* ***.*.* *** * ****** :******::****** : ** .********** *****:*.:**************:****.******:.** *.************* **:*:********:*:** **********:***:**:**.*::*******:***** *:*****:***********:**************** *****.****.***.*************:*********************************************:*******:*:*************************************.*****.*****:**.**********:***:********:************ *.** * ***.***************************************:*****:***:****:*******.**********:*******:**** :********. ** :*:*** *:**************.***:*:****.:*::****:******:***:*********************************.*****:***.:****..**** :. .: ****:.*..: *:* :****:*:.. :* .**.*.: : * .:* *** :. .:. :********: : ***********.*::**:***********************.**:* *::* .:.*:***", "identical_positions": 616, "similar_positions": 116, "identity": "78.17%" }, { "cls_id": "homologset.agr.MGI:2143702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DYE8-1", "uniprot_id": "ENPP3_MOUSE", "id": "Q6DYE8-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "aln": "---------MDSRLALATEEPIKKDSLKKYKILCVVLLALLVIVSLGLGLG-LGLRKPEEQ-GSCRKKCFDSSHRGLEGCRCDSGCTGRGDCCWDFEDTCVKSTQIWTCNLFRCGENRLETALCSCADDCLQRKDCCADYKTVCQGESPWVTEACASSQEPQCPPGFDLPPVILFSMDGFRAEYLQTWST-LLPNINKLKTCG----IHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVHLNKNFSLSSVEKSNPAWWSGQPIWLTAMY--QG---LKAACYYWPGSDVAVN-----------------GSFPTIYRNYSNSVPYERRITTLLQWLDLPKAD-RPSFYTIYVEEPDSAGHSSGPVSAG------VIKALQSVDNAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPKIN---------FYMYQGPAPRIRTRNIPQDFFTFNSEEIVRNLSCRKP-DQHFKPYLTPDLPKRLHYAKNVR--------IDKAHLMVDRQWLAFRSKGSSNCGGG--------------THGYN-NEFKSMEAIFLAHGPSFIEKTVIEPFENIEVYNLLCDLLHIEPAPNNGTHGSLNHLLKTPFYKPSHAGELSTPADCGFTTPLPTDPLDCSCPALQNTPGLEEQANQRLNLSEGEVAATVKANLPFGRPRVMQKNGDHCLLYHRDYISGYGKAMKMPMWSSYTVLKPGDTSSLPPTVPDCLRADVRVAPSESQKCSFYLADKNITHGFLYP-AIKGTNESRYDALITSNLVPMYKEFKKMWDYFHEVLLIKYAIERNGLNVVSGPIFDYNYDGHFDAPDEITQYVAGTDVPIPTHYFVVLTSCKDQTHTPDSCPGWLDVLPFIVPHRPTNIESCSENKTEDLWVEERFQAHAARVRDVELLTGLDFYQEKAQPVSQILQLKTYLPTFETII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97675-1", "uniprot_id": "ENPP3_RAT", "id": "P97675-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "aln": "---------MDSRLALATEEPIKKDSLKRYKILCAVLLALLVIVSLGLGLG-LGLRKPEEHIGSCRKKCFDSSHRGLEGCRCDSGCTDRGDCCWDFEDTCVKSTQIWTCNSFRCGETRLEAALCSCADDCLQRKDCCTDYKAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWST-LLPNINKLKTCG----LHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMY--QG---LKAASYYWPGSDVAVN-----------------GSFPNIYRNYSNSVPYESRIATLLQWLDLPKAE-RPSFYTIYVEEPDSAGHKSGPVSAG------VIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEIN---------FYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKS-DQHFKPYLTPDLPKRLHYAKNVR--------IDKVHLMVDRQWLAYRNKGSSNCEGG--------------THGYN-NEFKSMEAIFLAHGPSFKEKTVIEPFENIEVYNLLCDLLHIQPAPNNGSHGSLNHLLKAPFYQPSHAEELSKSAGCGFTTPLPKDSLNCSCLALQ-TSGQEEQVNQRLNLSGGEVSATEKTNLPFGRPRVIQKNKDHCLLYHREYVSGFGKAMKMPMWSSYTVPKPGDTSSLPPTVPDCLRADVRVDPSESQKCSFYLADQNIDHGFLYPPAIKGNNESQYDALITSNLVPMYKEFKKMWDYFHKVLLIKYAIERNGVNVVSGPIFDYNYDGHFDAPDEITNYVAGTDVPVPTHYFVVLTSCKNKTHTPDSCPGWLDVLPFVVPHRPTNVESCPENKAEDLWVEERFKAHIARVRDVELLTGLDFYQEKTQPVSEILQLKTYLPTFETII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14638-1", "uniprot_id": "ENPP3_HUMAN", "id": "O14638-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "aln": "---------MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLG-LGLRKLEKQ-GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDT-LMPNINKLKTCG----IHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMY--QG---LKAATYFWPGSEVAIN-----------------GSFPSIYMPYNGSVPFEERISTLLKWLDLPKAE-RPRFYTMYFEEPDSSGHAGGPVSAR------VIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINF--------FYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKP-DQHFKPYLTPDLPKRLHYAKNVR--------IDKVHLFVDQQWLAVRSKSNTNCGGG--------------NHGYN-NEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQ-NSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLT--IVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED-------KYTVYVNGNFPKEWNFNDGKN------HHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQG-YIEPFQNTEIYNLLCDICGVAEKDRNSNDGTG--MLMNQLREPQSSEEV--------------------------------EIEDDFDYLVSKFGEFSTYNIIWGG---YPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK-------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDNGPRTIANRSNTYFNGTHDFKTLT--ILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSN-TADPIWQLLQTESQG--EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIPNVDSYGHSFGYDLRD----KRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNNE-VVPPFENIEVYNMLIKASALLGEEKTKKEKS----LLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: * * * . . .. . *::*:***:. : * :: :: :*: : :* . :**:*****:::*** ** ***:.* ::* ..:* . : :*:* :* *.* : ****:* * : :. . ::: ::.::*:. . ** : *. : *: ** * . : : ** : *:*.*::*** . *:::::****.: : : : . :** : :: . . : : :: :. :: :: . . : . :. : : : . * .***: *: .* ::*:. ** * : : **:* *:**:: . : .. .. : * ", "identical_positions": 82, "similar_positions": 127, "identity": "8.6%" }, { "cls_id": "homologset.agr.MGI:2143755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0J9YVH3-1", "uniprot_id": "A0A0J9YVH3_MOUSE", "id": "A0A0J9YVH3-1", "name": "", "aln": "MAAVTYEDVHVNFTHEEWVLLDPSQKSLYKDVMLETYWNLTAIGYKLEDLNSEEHSQRSRRYGRHKICHSEYKPCELKGYGKKQCTFADKRFLQIYGRIHTEGKPYECKQCSQIFTNFCHLRKHEKKHTKEKLYECNHCGKSFPSRNSLQIHNRTHTGEKPYDCNECGKAFTCSSNLLLHKRTHTGEKPYDCSDCGKAFASSSNLQIHKRKHTGEKPYGCNQCGKAFAYSNALQKHERSHTREKIYECNQCGKAFARHRSLQNHEEHHTLEKPYECSQCGKAFAYSSNLYIHERSHTGEKPFKCTQCGKAFPSHSSLQIHERTHTGEKPYDCNECGKAFACRSNLLLHKRTHTGEKPYHCIECGKAFACSSSLQKHEKTHTGEKPYECNQCGKAFARRSDLYIHERIHTGEKPYECNQCGKAFVHCISLQRHERTHTGEKPYECNQCGKAFTRRFSLQVHERSHSGEKPYECNQCGKAFASRSSLRYHRKHHTAKKPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2QC13-1", "uniprot_id": "A0A0G2QC13_RAT", "id": "A0A0G2QC13-1", "name": "", "aln": "-AAVTYEDVHVNFTHEEWALLDPFQKSLYKDVMLETYWNLTAIGYKLEDLNSEEHSPRSRRYERHNICHSGYKPCERKGYGKKQCTFASKRFLQIYESIHTEGNPYECKQCSQIFANLYHLQKHEKKHTREKLYECNHCGKAFPSRNSLQIHNRTHTGEKPYDCNQCGKAFTCSSNLLLHKRTHTGEKPYDCNDCGKAFASSSNLQIHKRKHTGEKPYGCNQCGKAFAYSNALQKHERSHTREKIYECNHCGKAFARRRSLQNHEEHHTLEKPYECSQCGKAFAYSSNLYIHERSHTGEKPFKCPQCGKAFPSHSSLQIHERTHTGEKPYDCNECGKAFACRSNLLLHKRTHTGEKPYHCIKCDKAFACSSSLQKHEKTHTGEKPYKCNQCGKAFARRSDLYIHVRIHTGEKPYKCSQCGKAFVHCISLQRHERTHTGEKPYECNQCGKAFTRRFSLQVHERSHSGEKPYECNQCGKAFASRSSLRYHRKHHTVKKPN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****************.**** ******************************** ***** **:**** ***** ***********.******* *****:***********:*: **:*******:***********:***********************:**************************.********************************************************:*******:**********************************************.********************************************************:*.**********************:***************** *********:*.****************************************************************************.****", "identical_positions": 468, "similar_positions": 20, "identity": "93.98%" }, { "cls_id": "homologset.agr.MGI:2143792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y1D0-1", "uniprot_id": "A0A8I5Y1D0_RAT", "id": "A0A8I5Y1D0-1", "name": "", "aln": "-MAASSSSGLAQGA----SPSS-TQPSSTLSLPATGASYTVPSTPRMKSTVSLALA--------PTSQP------PAPRGGVTVGYSCSQPHP----------------SQGPTSNSRSRGPVPTTASTHQEDG------------------------HSCREKATKSRTDSRERP---ARSLSR----PGPSSRSPDSDSVSP----------------------------DSWGGPVLGPWDP---------------------TFTSDALP------------------------------FLDRLPKPKAGPRPPSMHYCEVCRVSCAGPQTYRDHLEGQKHRKKQAAQRTRTQPSGGPRGSQS-LHCGLCAVSCTGADAYAAHMRGARHQKVFKLHTRLGKPIPSEPTPRSVTYTRGSDSTPETSVKHEAHARHSSHTQGR-PAPAKGPAASRKGSP------ELQTVHSWP--------GDRRPSHCKAEA----TRGGSGEASGISGD-TEPVGTEYVEQVCSEEGKVIRFRCKLCECSFNDRNARDMHLTGRRHRLQYRKKVDPTLPVATRPSGPMQRVLAKRLQRQRQQ--TQARLEDAQRWNSELRQQEEHSRQPEEPPQPQVEEQLPGSPTWALPAPTTRP-GMASPRRQSGRRPESSDDRHVMYKHASIYPTEEELQAIQTAVSHTERALRLVSDTLAEES-------SQQGTLVSPPP---------------------RMLKGVVRVGILAKGLVLRGDHSVQLTLLCSKKPTHSLLQRIKQELPRELSIVAED---KYEVSSD-HDANIVISACVEPGVKVTVSATSPLMREDPSVKQELQDSLSDPEDILDRERCLETLAALRHAKWFQARASGLQPCVIVIRVLRDLCRCLPPWGALPAWAMELLVEKVLSSAPRPLSPGDAMRRVLEYVATGALLTDGPGLQDPCEKGPQDALEPMTPQQREDLTASAQHALRLVAFRQIHKVLHMEHLPPRTRFGA-----RKRMREASQT--------------QEGARERKRGRQGTAGLP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5M4-1", "uniprot_id": "E9Q5M4_MOUSE", "id": "E9Q5M4-1", "name": "", "aln": "-MAASSSSGLAQGT----NPSSSTQSSSAFPLPATGASYTVQFTPKMESTASLALA--------PASQL------PAPGGGVAVGYSCSQPQA----------------SQGPTSSSQPRGPVPTSASAHQEDG------------------------HSYREKVTKSRTDSRERP---ARSLCR----PGPSSRSPDSDSVSPGPQRPPPSSQRAPQKLQAPSPPPAPVGSDPWGGPVLGPWDP---------------------TFTSDALP------------------------------FLDRLPKPKAGPRPPSMHYCEVCRVSCAGPQTYRDHLEGQKHRKKQAAQRTSTQPSGGPRGSQS-LHCGLCAVSCTGADAYAAHMRGARHQKVFKLHTRLGKPIPSEPTPRSVTYTRGSDSTPETSVKHEAHARHSSHTQGR-PAPAKGSAASRKGPP------ELQTMHGRP--------GDRRPSHFKVEA----TRGGPGEASGSSGD-MAPVGTEYVEEVCSDEGKVIRFRCKLCECSFNDRNARDMHLTGRRHRLQYRKKVDPTLPVAARPSGPIQRVLAKRLQRHWQQ--VQTQLEDTRRWDSELRQQEEHSRQPEETPQPQVEEQLPGLPAWALPAPTTRP-GMATARRQSGRRPESSDDRHVMCKHASIYPTEEELQAIQTAVSHTERALRLVSDTLAEES-------SQHGTLASPPP---------------------RMLKGVVRVGILAKGLVLRGDHSVQLTLLCSKKPTHSLLQRIKQELPRELSIVAED---KYEVSSD-HDANIVISACVEPGVKVTVSATSPLMREDPSVKQGQQDALSDPEDVLDRERCLETLAALRHAKWFQARASGLQPCVIVIRVLRELCRCLPPWGALPAWAMELLVEKVLSSAPRPLSPGDAMRRVLEYVATGALLTDGPGLQDPCEKGPQDALEPMTPQQREDLTASAQRALRLVAFRQIHKVLHMEQLPPRTRFGAGA-RARKRMREASQA--------------QEGTRERKRGRQGTAGLP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPR6-1", "uniprot_id": "ZFR2_HUMAN", "id": "Q9UPR6-1", "name": "Zinc finger RNA-binding protein 2", "aln": "-MATSQYFDFAQGG----GPQYSAQPP-TLPLPTVGASYTAQPTPGMDPAVNPAFP--------PAAPAGYGGYQPHSGQDFAYGSRPQEPVPTAT----TMATYQDSYSYGQSAAARSYEDRPYFQSAALQSGRMTAADSGQPGTQEACGQPSPHGSHSHAQPPQQAPIVESGQP---ASTLSSGYTYPTATGVQPES-SASIVTSYPPPSYNPTCTAYTAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQLPPPPAPAGSGSSPRADSKPP-----------------------------LPSKLPRPKAGPRQLQLHYCDICKISCAGPQTYREHLGGQKHRKKEAAQKTGVQPNGSPRGVQAQLHCDLCAVSCTGADAYAAHIRGSKHQKVFKLHAKLGKPIPTLEPALATESPPGAEAKPTSPTGPSVCASSRPALAKR-PVASK---ALCEGPP------EPQAAGCRP--------QWGKPAQPKLEGPGAPTQGGSKEAPAGCSD-AQPVGPEYVEEVFSDEGRVLRFHCKLCECSFNDLNAKDLHVRGRRHRLQYRKKVNPDLPIATEPSSRARKVLEERMRKQRHL--AEERLEQLRRWHAERRRLE------EEPPQ-DVPPHAP--PDWAQPLLMGRPESPASAPLQPGRRPASSDDRHVMCKHATIYPTEQELLAVQRAVSHAERALKLVSDTLAEEDRGRREEEGDKRSSVAPQT---------------------RVLKGVMRVGILAKGLLLRGDRNVRLALLCSEKPTHSLLRRIAQQLPRQLQMVTED---EYEVSSD-PEANIVISSCEEPRMQVTISVTSPLMREDPSTDPGVEEPQADAGDVLSPKKCLESLAALRHARWFQARASGLQPCVIVIRVLRDLCRRVPTWGALPAWAMELLVEKAVSSAAGPLGPGDAVRRVLECVATGTLLTDGPGLQDPCERDQTDALEPMTLQEREDVTASAQHALRMLAFRQTHKVLGMDLLPPRHRLGAR---FRKRQRGPGEG--------------EEGAGEKKRGRRGGEGLV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8G8-1", "uniprot_id": "A0A8M2B8G8_DANRE", "id": "A0A8M2B8G8-1", "name": "Zinc finger RNA-binding protein", "aln": "MMAASNYYGFTHAAAAAAGPQYSTQPPPAYSHPTTG-SYNVQPAPGVAHAVTASYPAPTAQPARPAVTAPYPTYQPHPAPNYGYRQPETTPQPTTTPQTYQVLTEPENYTYGRPPPVSSYENKQYFQTSIAPAQRPATEAYFQTGLKSG----YSPASTAYNQPPVQRQVAALKPPPAVSSVSSSYTIYPTSTSVQQSPAPISTYTPSSSFNSTAATSYSAGLNYSSYDSSGYTSTPSYYQPAQCAPPQAQPQPPLQPPQQQPQPPPPQQTQQPPKQLANSSWSNSGGSSVSSPAVSSYRKPAFHQNKIQKPKGPPKQPQLHYCDICKISCAGPQTYREHLEGQKHKKKEVAQKSGSQVTNGPRGVQTQLRCELCDVSCTGADAYAAHIRGSKHQKVVKLHTKLGKPIPSTEPVLVSSTPAAMTTTISKPAASTSSTPTSAAQKIQTAAPPKPAAAPVKKPPPAVSAAKAPAVVSKPSTSAVVKMEEVKPPVVKTDPS---SDDEDADATGPQGD-IQPVGHDYVEEVRNDDGKVIRFHCKLCECSFNDPNAKDMHLKGRRHRLQYKKKVNPDLPVEIKPSNRARKLLEVKLRKQKQKSVLKRQQEDEQRWHMEMSRRYEEDMYWRRMEEEQVYWAEPR-RRMAPPPLMGRP-SIPVPPLLPVRRPDSPDDRHIMAKHSAIYPVEEELQAVQRIVSYSERALKLVSDTLLEKVACADDDESETDKQSETQS---------------------RTLKGVMRVGILAKGLLLRGDRNVQLILLAANKPTVSLLKTVAEQLPKQLATFSED---QYEVQVHPEEANIVIFSSKEPKMQVTISLTSPVMREDP-VPNMEKVSEKDPPDLLNRIKCLEYLAALRHAKWFQARANGLQSCVIIIRVLRDLCQRIPTWGKMPNWAMELIVEKAISSASGPLSPGEALRRVLECIATGILLPDGPGLLDPCEKGQTDALGTMSKQAREDVTANAQHALRLLAFRQIHKVLGMGSLPVSKAAARN----RKRRRDGSDV--------------GEGEADGKKDKKDDSNDP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BI3-1", "uniprot_id": "Q86BI3_DROME", "id": "Q86BI3-1", "name": "", "aln": "-MANNNYAGFNYGG-----TQYNTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGG-------AAGAGAGATSGPGAGGYGGYGDYRS------------------AMQYDATKTFYQQSPASYNASGSTASVS----------------------KTHYSAPPVKNQVKGKMDK---SNGGPK-----PPSSAPPAGNNYSG---YDTALYNAASMYVAQQHQGNPNQKPNGGANNWYQRKMG--------------------ATIPG---------------------------------ATAIRGMRPKAPPRPQQLHYCEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNRGNNYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKLGKPIPSEEPKKMGKINFVPAAAGGAGVAKTEGGANESDAAGD-------------------------------------------------------LDDNLDDSLGENTDNIKPVGGEYIEEVKDEEGKILSFNCKLCDCKFNDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRGGDDHDGGYWEEQRNRQYN-----EEYDYNNWMSRSFGGAQRFGRMGNGPPPHFGMMPGGNVRRPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIVL---DESVSVKITLTSPLLRDANPGEAATTDEGEGDSEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSLPQWSLELLVEKVISSAGFPISPGDCMRRIMEALSSGFLIN-GPGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAGGAPGTETESNDIDETGSDEKVAKKEGVGGTPAST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .. .: . .. : . . . : . : . .: * . . . : : : .:. * . : :**. *: .:***::*::*********:** ****:*::.: : . ....:. :* ** *:***:******:**::****.*** :******: . : . . . :: . * *** :*:*:* .::*::: *.****:*.*** **:::*: ********::**:* * : .*: ::: : .: .: *. : : .. : * *** *.**** : :*: *** *:** ::* **::****:****:* *: . . * ****:*** *****:*:**. *.* :*.::*** .**: : : ** :* .: * :*.*. . :* ::: : :.*.:: ***::*: . :.* **. ** ****:******.***.**::**:**:**: :..* :* *::**:***.:*** *:.**:.:**::* :::* *: **** ****:. *** :: * ***:*..** ** :**** :*** * ** *** * .. * : :.. . ", "identical_positions": 234, "similar_positions": 199, "identity": "21.97%" }, { "cls_id": "homologset.agr.MGI:2143854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52590-1", "uniprot_id": "NU107_RAT", "id": "P52590-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGGMSSPVIRDPEVTRTARKHSAHKRVLIQANQDENFGT-TTPRSQIIPRTPSS-FRQPFTPPS-RSLLRHPDISYIFGTEG-RSPRHIQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGFYTNTEHHSMTEDINLSTVMLREDDPGEAASMSMFSDFLQSFLKHSS-TTVFDLVEEYENICASQVNILSKIVSRATRWDWQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLE---EENMFAIAGINASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGDFSDNIEFYAKSVYWENTLHSLKQRQLLSYIGSTRPLVTELDPDAPIRQKM-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLHHDPNVNGG----TELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIRTS--VMTLDETEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHVVQKFLILGDIDGLMDEFSKWLSKSRSSLPGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLINEKHTNLIAFYTCHLPQDLAVAQYALFLEGVTECEQRHQCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPSLDTATTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNERFKHMNSAPQKP----TLLSQATFTEKVAHEHKEKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEED-------PERAHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH74-1", "uniprot_id": "NU107_MOUSE", "id": "Q8BH74-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGGMSSPVIRDAEVTRTARKHSAHKRVLIQANQEDNFGT-ATPRSQIIPRTPSS-FRQPFVTPSSRSLLRHPDISYILGTEG-RSPRHTQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGLYTNTEHHSMTEDVNLSTVMLREDDPGEAASMSMFSDFLHSFLKHSS-TTVFDLVEEYENICGSQVNILSKIVSRATPG-LQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLE---EENMFAIAGINASEKMVVETLFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHSLKQRQLLSHMGSTRPLVTELDPDAPIRQKL-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGG----TELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIRTS--VMTQDDSEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDVDGLMDEFSKWLSKSGSSLPGHLLRFMTHLILFLRTLGLQTKEEV-SIEVLKTYIQLLISEKHTSLIAFYTCHLPQDLAVAQYALFLEGVTEFEQRHQCLELAKEADLDVATITKTVVENICKKDNGEFSHHDLAPSLDTGTTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNEWFKHMNSAPQKP----TLLSQATFTEKVAYEHREKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEDD-------PERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57740-1", "uniprot_id": "NU107_HUMAN", "id": "P57740-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGN-TTPRNQVIPRTPSS-FRQPFTPTS-RSLLRQPDISCILGTGG-KSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSS-STVFDLVEEYENICGSQVNILSKIVSRATPG-LQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALE---EESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKM-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGG----TELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIQTS--VATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKP----ALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKED-------HERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGI2-1", "uniprot_id": "Q5RGI2_DANRE", "id": "Q5RGI2-1", "name": "Nuclear pore complex protein", "aln": "MEWS--QTWLSPVVRDAEVTRAARRKSSHKKVAFPLAQDDSPGTSTTPARPLLRQTPGPRLKQTFTPRS---ALRNPDVSAILGTSGSRTPRFVNTPRTKGGLSMN--LDDSDWTNSLYPSP---LSGIVDTSFTDDVSMSALMLKEDDPGEAASLGLFPEFLESYLRHAS-TAVFDLLEEYEALCQDKVSVLQKLVLRSAPG-QQKSSKTVSITWLLQQEMVTWRLITSLYRDRVQTVLE---EDIMMDITMPSESEKAVMEQFFQKDSMVRQSQLVVDWLESIAKDDIGDFSDNIEYYAKSVYWENTLHTLKLRRNQSSGGLSRPLVTELDPDAPIRQKR-PLADLDREDDSRLLKNLFNLIRAGMTDEAQRLCKRCGQAWRAATLEGWKLYHDPNINGGG---GELQPVEGNPHRSVWKVCCWRMAEEEQFNKYERAIYAALSGNLKQLLPVCES-WEDTVWAYFRVMVDTLVEQEICSS--GLGSEELEELPRDFLETNWTLEKVFEEIQATESKRVLDATKEHYHVIQKFVILGDLDGLLEEFSDWLGRN-TPLPAHLLRFMSHLVLFYRSLGMQLKEEV-CVDVLKAYISLLVKEKQVELIAFYVSHLPADLAVSQYAQFLEEVTETEQRKHCLELATQAGLEVAAITKTVVETIRERDTDEFSHHDLTPALDTATTVEDQQKIDVIDWLVFDPAQRAEALKQSNAIMRKFLASKKHDAAKMVFAKVPEDSMREIYRQWEEQGMDTPLPAEE--ENAIREHLCIRAYLEAHEAFNEWFKHMNCPPVKP----TAPAQAKFTEKVAHEMKEAEYKIELENWQGRLGALTEDVKERIYNVLLFVDGGWMVDVREDAEED-------SERSHQMTLLRRLCLPMMSFLLLTVLQRTERHQESLRLADIIASDQHKLYEVFSKDELQKFLQKMRESSLLLLDKGLDPLGYEIQP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V466-1", "uniprot_id": "NU107_DROME", "id": "Q9V466-1", "name": "Nuclear pore complex protein Nup107", "aln": "-------------MADSPFPRSSRSGLLRTTLNSSMPPQNLSHS--------------------------------------------------------------------------------LLILEKSNAEQNELSLMEDTGDDLDRGKSRMDVLFPQFFDVLQAQGNGQEAFEVIQSLTQVCRGVVEQLELEIDHGMGG-EQGARQRESMLTWLRQEINTWRLLHALFYDRILLQTDRQADDEMQDGPTLGGSEKEVIQQLYALNATLREYQLVVDWLEACYD--RGEQQNPLHAHDRMMAWENTLFQLENLQG-AAFGKGHKIVTRLDPDAPVREKR-PLHALDEEDNLRLSRAIFELIRAGRVDDGLKLCKHFGQTWRAAILEGWRLHEDPNFEQNVSVLHEKLPIEGNPRRDIWKRCAWMLADSKNYDEYSRATAGVFSGHLGSLKTLLHSNWHDLLWAHLKVQIDIRVESEIRGC--CLKN--YQPMPDDYWNGRMTMEQIFEELNVAKDASVRDFAQSQLGIIQRHLILDTCGELIQHMVRWVEKDTSQQSPHQLRFMAHIVLFLRQIGRVEQERQ-AEKIVAAYVEALIARGEPQLIAYYTASLSNPLQVQLYSRFLEQVEQKRPRELAVDAALQAGLDVEQITRVTVQNIRLAHQP---LGEFGEPQSGEISAIDQRKISALEWLIHLPEQRGELLWQANAMIRTYLASSKVECMRQTFRMVPADIVQQLVSLY---GSVDNIPPRE--ECCLKEYLCYKAYLSGVDSFVEWNRLQQNRPKKPQTSHAASSQDNFTERMASERKEQAHRSEVVRWEHKVKEQAKQTIELLYNVLMFPDKGWLVDPFIAKLPENAVQLSWDHRLLQMEKLRSICIPEIALFLNEVMFKSGDFAGCVRLADEISSENRQLYKVYTKHKLAELLAKIADASLELLNSKLDPWGYPITT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52891-1", "uniprot_id": "NUP84_YEAST", "id": "P52891-1", "name": "Nucleoporin NUP84", "aln": "------------------------------------------------------------------------------------------------------------------------------MELSPTYQTERFTKFSDTLKEFKIEQN--------------NEQNPIDPFNIIREFRSAAG------QLALDLANSG--DESNVISSKDWELEARFWHLVELLLVFRN-ADLDLD---EMELHPYNSRGLFEK----KLMQDNKQLYQIWIVMVWLK------ENTYVMERPKNVPTSKWLNSITSGG--------------LKSCDLDFPLRENTNVLDVKDKEEDHIFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEYLNPVIDTQIAN--EFNTQQGIKKHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEVLQYSDWESDLHIHLNQILQTEIENYLLENNQVGTDELILPLPSHALTVQEVLNRVASRHPSESEHPIRVLMASVILDSLPSVIHSSVEMLLDVVKGTEASNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYISLLKLQGLYENIPIYATFLNESDCLEACSFILSSLEDPQVRKKQIETINFLRLPASNILRRTTQRVFDETEQEYSPSNE-ISISFDVNNIDMHLIYGVEWLIEG-KLYVDAVHSIIALSRRFLLNGRVKALEQFMERN---NIGEICKNYELEKIADNISKDENEDQFLEEITQYEHLIKGIREYEEWQKSVSLLSSES---------------------------NIPTLIEKLQGFSKDTFELIKTFLVDLTSSNFADSADYEILY--------EIRALYTPFLLMELHKKLVEAAKLLKIPKFISEALAFTSLVANENDKIYLLFQSSGKLKEYLDLVARTATLSN------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . : . . *:::.. . . : . : * *. .: : :: : : : : . ** : : : : :*: **: . * *:: :. * * *:*:: * *.*:: : : :: ** ** ::. . .* .: . * * : : :* .: * . :* : :*: : :::. : *.** . :** : . : : *.. : ::. :: :*. : :* . . .:::: .. .. : . :* . *:: . . : **:::*: : :. *. .:: :*:. * . . *. *. * : : :*. : : . *. :: * . * : ..: : : . . . * * ::**: : : . *: * :* : .. . : : :: :. : : :.* . :.. : * : . . :. : :: : :. * : ..*: . :.* . : : : . :: . .: ::. ::.:. ::* :: . : .: : * : ", "identical_positions": 65, "similar_positions": 225, "identity": "6.8%" }, { "cls_id": "homologset.agr.MGI:2143886", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZRT2-1", "uniprot_id": "A0A8I5ZRT2_RAT", "id": "A0A8I5ZRT2-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "aln": "--MGEKLELRLKSPVG-AEPAVYPWPLPVYD--KHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMK-LNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQR---ENKSNATTPTKVPESKAA-ATEAPADSGAEEEKSGVATVKKQSPSKARKKKLNK--------------------------------------------------------------------------------------------------KGRKMAGRKRGRPKKMSAASA-DRKSKKSQSTLDLLHSPPPAPPSAS-PQDAYRAPHSPFYQLPPSTPLHSP--------------------------------------DPLLVAP----------------------------TPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEEL--------------RLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGR-ELESDAGRLRLELDCAKLSLPHLSSMSPELSMNGHAAS-YELCGAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHAKENSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSERGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSSTLEKQIGASTHGAGGAAAGSRSLTVAPTGF-YAGSVA---ISGALASSPAPLASGMESAVFEESSGPSSLFGTMGSRSTPPQHPPLLPQSRNSGPASPAHQLAASPRLSVT---TQGSLPDTGKGELPADPAFSDPESEAKRRIVFSISAGA-SSRQSPSTRHSPLTSGTRGDCVQSHGQDSRKRS---------------RRKRASAGTPSLTTGVSPKRRALPTVAGLFTQSSGSPLNLTSMVSNINQPLEITAISSPESSLKS-SPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPG---SEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKPVPS-------------GEPVNSSKWKSTFSPISDLG----LAKAMDSPLQASSALS-HSPLFSFRPSLE-----EPAAEAKPSTHPRKSFAGSLAAAEG----------------------------------------PSPGTNPPNSLAFSGGLAADLGLHSFNDGASLSHKGPEVAGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNASKESGES-LPLCGPSDKVS---LPHGSRASKGRDRELDFKGGHNLFISAAAVPPGG----LLGGPGLVTVASSAGSATPSAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAG-LVHVSSTATRLTNSHTMGSFSSGVAGGTVG--------GN----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6XZL8-1", "uniprot_id": "DOT1L_MOUSE", "id": "Q6XZL8-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "aln": "--MGEKLELRLKSPVG-AEPAVYPWPLPVYD--KHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMK-LNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQR---ENKSNATTPTKVPESKAA-ATEAPADSGAEEEKSGVATVKKPSPSKARKKKLNK--------------------------------------------------------------------------------------------------KGRKMAGRKRGRPKKMSAASA-ERKSKKSQSTLDLLHSPPPAPPSAS-PQDAYRAPHSPFYQLPPSTQLHSP--------------------------------------NPLLVAP----------------------------TPPALQKLLESFRIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEEL--------------RLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGR-ELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAAS-YELCNAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHPKESSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSEKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSATLEKQTGASAHGAGGAGAGSRSLAVAPTGF-YAGSVA---ISGALASSPAPLASGMESAVFDESSGPSSLFATMGSRSTPPQHPPLLSQSRNSGPASPAHQLTASPRLSVT---TQGSLPDTSKGELPSDPAFSDPESEAKRRIVFSISVGA-SSKQSPSTRHSPLTSGTRGDCVQSHGQDSRKRS---------------RRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPESSLKS-SPTPYQDHDQPPVLRKERPLGLTNGAHYSPLTSDEEPG---SEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKSAPS-------------SEPINSSKWKSTFSPISDLG----LAKAVDSPLQAGSALS-HSPLFSFRPSLE-----EPAAEAKLPTHPRKSFAGSLGAAEG----------------------------------------PSPGTNPPNGLAFSGGLAADLGLHSFNDGASLSHKGPDVTGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNANKESGES-LPLCGPSDKAS---LPHGSRASKGRDRELDFKGGHNLFISAAAVPPGG----LLGGPGLVTVASSAGSATPTAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAG-LVHVSSTATRLTNSHTMGSFSSGVAGGTVG--------GN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEK3-2", "uniprot_id": "DOT1L_HUMAN", "id": "Q8TEK3-2", "name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "aln": "--MGEKLELRLKSPVG-AEPAVYPWPLPVYD--KHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMK-LNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQR---ESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNK--------------------------------------------------------------------------------------------------KGRKMAGRKRGRPKKMNTANP-ERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSP--------------------------------------NPLLVAP----------------------------TPPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEEL--------------QLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGR-ELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAG-YELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAG-----SRSLALAPAGFSYAGSVA---ISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGA---AQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRG---------------RRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKS-SPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPG---SEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPA-------------GEPVNSSKWKSTFSPISDIG----LAKSADSPLQASSALS-QNSLFTFRPALE-----EPSADAKLAAHPRKGFPGSLSGADG----------------------------------------LSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKE-GSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGPTDKTP---LLSG-KAAKARDREVDLKNGHNLFISAAAVPPGS----LLSGPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSSVPAAAG-LVHVSSAATRLTNSHAMGSFS-GVAGGTVG--------GN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58II20-1", "uniprot_id": "A0AC58II20_DANRE", "id": "A0AC58II20-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "aln": "--MGEKLELKLKSPVG-AEAAGYPWPLPVYD--KHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMK-LNKRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQIIDEMEMMEEDTFVDLGSGVGQVVLQVAAATNCKHYYGVEKADIPATYAESMDKEFKRWMKWYGKKHGEYTLERGDFLSEEWKERIASTSVIFVNNFAFGPEVDHQLKERFANMKEGGKIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLRGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEVARRRPQKDSKENKSNTTTPTKPKEHKQA-----QHDSGGEEEP--VVPVK-PSP-KPRRAKILT--------------------------------------------------------------------------------------------------RGRKLGNRKRGRPKKAPAATAAERKNKKSQSALDLLHAKTLS---AAPAQEPYRSPQSPFYQLPPKVQHYTS--------------------------------------SQLLMAP----------------------------TPPGLQTLLDNIKVQYLHFMAYMKTPQYRTNLQQSLEQEKLRHTELSSQAQQLVNACHAHKERIHDLFQSKLEELGVKAVTVEDLVQAQKEITAHNMQLREQTKQLEHDMAELRDQSQLLLKARCEEL--------------KLD--TLCWDTLKKEIEALRRQISEKQRHCLELQISIVELEKSQRQQELLQLKSSYSPCEVSPYRKALPGPDPRPTLDPDTPKLTPQSSMG------LNGLSPELSINGTASPGYERCTGSAMGKNELLT-HYLPISPDHEIVPPTPDSRTR-----QLGQPLPDYTRFSPAKIALRRHLNQDSAANQFRALGNIHRG------------DTGAISSPTLGFKQASPCSSEVQAVTTAKNTDRADKEKSPTAPGDTITSLPISIPLSTVHPSKLPVSIPLASVVLPNRVERLRSTPSPVLNPAGQSN--GKPPLTPTSGTG-----------------YSSSSG---LVNGSHSTMLTEDQDCDVASPPPHSTPVMGLQPRGSGLSPPLGTGGVLQYADGPPRLPPEDGHERQGPESD---TEPLDSEARRRIFFSSSSSSSSSSSSTGGSRLHHGSVK-QGHHHHSKHHHHHHHHHHHHSPSSHSQEGRKRG---------------RRKRSSSGAVPMSG--SPKRRVFPGLG-CSSHSSGSPLNINSMVNNINQPLEISAISSPEQSGRS-PCG--QDLDQPPVLKRERPLELNNTGRYSSAPSSDEEGNGYAPDTSSSSRIERKIATISLDRDGPVRDLERG--LQGRKSGASSVSSEV-------SSSSGTSKWKSTFSPISDPKPTPPDIRQGGSPFSVGASRGGTDSDSDHKPQRRGEREREPYGNSNLFLSQDGSGRSAVNTSERS--------------------------------------LQKQKVREWDLKSVSGLASQNLFISAAASGGILSGKVGGAATVSSASAVGQYFPLGGASVLQPLFG-TQAAGPATSGAPRLVNGHSALGSFSSAGLAGGAAGGIFHHMVSSSSSQQSGPNLPSSHNSQQRHLDTNPKAGASFLASGPNRTQTVLHAPSPPTLALPPPPPLLNTVPSQPSSPRSSRPQSSIPVATSSQSLAAASSSCTSSASSRPFTVHYPPHLQPPGSAGSGGTGASWRTLASYTASQIPGNRPR-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INR6-1", "uniprot_id": "DOT1L_DROME", "id": "Q8INR6-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "aln": "MATPQVKDLVLRSPAGSSDVISFAWPLQIGHGQDKHDNGIDIIDTIKFVCDELPSMSSAFEETNLHQIDTACYKTMTGLVDRFNKAVDSIVALEKGTSLPAERLNKFAHPSLLRHILQLVYNAAVLDPDKLNQYEPFSPEVYGETSYELVQQMLKHVTVSKEDTFIDLGSGVGQVVLQMAGSFPLKTCIGIEKADTPARYAERMDVIFRQYMGWFGKRFCEYKLIKGDFLVDEHRENITSSTLVFVNNFAFGPTVDHQLKERFADLRDGARVVSSKSFCPLNFRITDRNLSDIGTIMHVSEIPPLKGSVSWTCKPVSYYLHVIDRTILERYFQRLKTKGGNDHESVGTVRTTRDRAKREANVGQHHHNNHHSNNHANSNNHQRDREQSNGATATAAHQQRHQSQSPANVSGAGIVLAASGQQAASKTRQQLQHQHNQQQRSLDMESSTESDGDATNGNGGNTTTATNTTSASNGPMTRKVWSDWCSSKGKSSQSDDEENNNSNSNGGSNGGSIGGGSVGRQARATTQKKRKKLTRKAAIASKSAAAAQREAEAAAAAAVSVPSKESSSKEDPPRAASAGPGRKGRMKKGARGRKSLKIVGLEALHKQTVLSTSLDTMTKKLPAAPGTVDQQLTALLTENMSHAELDIPTAPQDTPYALQILLDVFRSQYTSMIEHMKSSAYVPQVQKQIAQEQERMARLKNRASQLDKQIKVLIDDSVALLKVRMNELGIHVNSPNDLIAQAKEIVGRHKDLQHTASRMRNEVTFYEGEQKLLLNKQLKNLPEYQKLCGTVNGKVKLEVPPELSETTAQELVLKEIANTLSQRKKLYAQVSTIEQETSVLQKTAEERSTAATLLAQGTNMIVSTGSSSSSSTTVCASAVTAQ--SNKLNSVKNSRRNREHRARSQEWPEVPEVGKIQESNPEVLAQKIVETCRQIEAGKFQGAGAPSSQVNGKNKAIIEVPPPPATAPVSIKSSPGHHYKDTTLMPAPKQQQQQQMTLSQLPKCELPGLSTSRKQESPKVANFEDRLKSIITTALNE--DQEQRSKAVESSPSPSPLHSPAPKRSKQHPAGAINPAQSLPNNLHNIITVSTQGLMHLNANTTISPITPPLPGPGAGATASTAPPPPANLPYGAYGGAVAKTTISGKYQAAKEPKYSPVRQAPLPPPPSHMASLYPAGQQTTPADLGYQRRRSSVSATSYEHYMVQQQQQLQQQQLMLAAAAHAAQRQQMRVEEQQQQQQHQHHHHHHHHHPQHRLPQHVQHQHPHQHHPNEFKAPPADSHLQRSSSREQLIVEPPQTQPLELLPRASSANSDYSGYRIRPPSRPSSNSSQPDYTQVSPAKMALRRHLSQEKLSQHVTPQATPPLPGHGGAPTSGKTIGDLVNGEIERTLEISHQSIINAAVNMSTSG-ASFMERAFLNERSNDRLLINLNAQRPERVHVRPLSEESQDPQPTSYAQERGPGLGAGGAAAGGNSNLATLAHVAYAQKAQGGARANAGTAPPATHSSSARSGRDYQPVALPRAELKGSIEAYFHEEQQQKQSKGAGSAGSSSLRGPRLNGANPPLEGLAASLQDHVRARKYKEETEERQRRAAAAASSSAGPPAGMELPTHYAHQAPPAHSYHHHGASINGTPHKVELGIKRSSPLAPHQQPPRPSKLAHYEPPTTQQQHAHAHLYANGQVLPPPPAHDATTPSPTPSSSSSSCGRRSNSNNGKLLVDPPLLMSPEIN--SLLGDERPLQLSHHQQQQQQMLHHHQSQQQQHLQLTQQQLRVAHLGHGLSHGHSTMPTLGGQRNGNGNAADDVNDLATQRTITNYDPRRRLRTTLSGPTKLSAAHSNQNLNGYVMADSSSSCPTIPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04089-1", "uniprot_id": "DOT1_YEAST", "id": "Q04089-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "aln": "--------MGGQESISNNNSDSFIMSSPNLD---SQESSISPIDEKKGTDMQTKSLSSYSKGTLLSKQVQNLLEEANKYDPIY------------GSSLPRGFLRDRNTKGKDNGLVPLVEKVIPPIHKKTNNRN----------------------------------------TRKKSSTTTKKDVKKPKAAKVKGKNGRTNHKHTPISKQEIDTAREKKPLKKGRANKKNDRDSPSSTFVDWN-----GPCLRLQYPLFDIEYLRSHEIYSGTPIQSISLRTNS----------------PQPTSLTSDNDTSSVTTAKLQSILFSNYMEEYKVDFKR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STAIYNP-----------------------------------------------------------------------------MSEIGKLIEYSCLVFLPSPYAEQLKETILPDLNASFDN-----SDTKGFVNAINLYNKMIREIPRQRIIDHLETIDKIPRSFIHDFLHIVYTRSIHPQANKLKHYKAFSNYVYGELLPN---------------------------------------------------FLSDVYQQCQLKKGDTFMDLGSGVGNCVVQAALECG-------------------------------------------------------------------------------------------------------CALSFGCEIMDDASDLTILQYEELKKR---------------------------------------------------CKLYGMRLNNVEFSLKKSFVDNNRVAELIPQCDVILVN-------------------------------------------------------------------------------------------------------------------------------------------------NFLFDEDLNKKVEKILQTAKVGCKIISLKSLRSLTYQINFYNVENIFNRLKVQRYDLKEDS---------------VSWTHSGGEYYISTVMEDVDESLFSPAARGRRNRGTPVKYTR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. . : : . . :: . . *: : . : .:. : * . : : *:: * *. . . :: * : .* *: : . : :.: * : *. . .. . .. : * :* .: :: :.: : : ** : * : . .: *...: .:.:* .. * *:: .. * :: ::..*:. * . . . :. : . :. . :: : : : . . . :. : : . : : :: : . . .:: :.::.: . ** . : . : : . . : : .. : : . . . .: . * .. : . : . .. . : : . : : : ", "identical_positions": 25, "similar_positions": 160, "identity": "1.35%" }, { "cls_id": "homologset.agr.MGI:2143897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FWS4-1", "uniprot_id": "CAHM5_RAT", "id": "Q5FWS4-1", "name": "Calcium homeostasis modulator protein 5", "aln": "MDAFQSILKFFLNQKTAIGYSFMALLTVGSERLFSLVAFKCPCS-IENTAYGLVFLFAPAWVLLILGFFLNNKAWRLFTGCCMNPQKIFPRRRCCRFFYVLGHITLSSLVAPVMWLSVALLNGTFYECAMSGTRSTRLLEMICKGKPKECWEELHKVSCGKSSMAAMDSEEVRLSLQAQSQILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQREKEQLENKLLEYANKLSERNLKCFFENKKPDPFPMPSFAAWEAASELHSFHQDREHYSTLHKVVDDGLEQTPQEEETTMILVGTAQSL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R100-1", "uniprot_id": "CAHM5_MOUSE", "id": "Q8R100-1", "name": "Calcium homeostasis modulator protein 5", "aln": "MDAFQSILKFFLNQKTAIGYSFMALLTVGSERLFSLVAFKCPCS-VENTAYGLVFLFAPAWVLLILGFFLNNKAWRLFTGCCMNPKKIFPRRRCCRFFYVLGHIILSSLVAPVMWLSVALLNGTFYECAMSGTRSTRLLEMICKGKPKECWEELHKVSCGKSSMAAMESEEVRLSLQAQSQILGWCLICSASFLSLLTTCYARCRSKVSYLQLSFWKTYAQREKEQLENKLLECANKLSERNLKCFFENKKPDPFPMPSFGAWEAASELHSFHQDREHYSTLHKVVDDGMEQTPQEEETTMILVGTAQSL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5C1-1", "uniprot_id": "CAHM5_HUMAN", "id": "Q8N5C1-1", "name": "Calcium homeostasis modulator protein 5", "aln": "MDAFQGILKFFLNQKTVIGYSFMALLTVGSERLFSVVAFKCPCS-TENMTYGLVFLFAPAWVLLILGFFLNNRSWRLFTGCCVNPRKIFPRGHSCRFFYVLGQITLSSLVAPVMWLSVALLNGTFYECAMSGTRSSGLLELICKGKPKECWEELHKVSCGKTSMLPTVNEELKLSLQAQSQILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQKEKEQLENTFLDYANKLSERNLKCFFENKRPDPFPMPTFAAWEAASELHSFHQSQQHYSTLHRVVDNGLQLSPEDDETTMVLVGTAHNM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4FUN9-1", "uniprot_id": "CAHM5_DANRE", "id": "A4FUN9-1", "name": "Calcium homeostasis modulator protein 5", "aln": "MDSFKTVLKFFTDQKTTIGYSVMAILTIGSERIFSMVSFQCPCTKGQNFPYGICFLLGPAVVLLVVGFFVSTRFWRLYTGCCLNPLKLCPRGNFVGCLKGLIKVLYGACVAPVMWLTVALLNGTFYECAVSGLDEVAVIQIFCADKGSVCQDELHRVPCGKSTLPPEQNTELLYMLRAQSQILGWSVIITAVVIALIGTCYKNCVSQVSYLQLTFWKIYMEKEREKFDAFANDYATKLADRNLKSFFDNKLPEEFPFPNHKAWEEISAIYNFRKSEQHYSTLQRYVER-SDRDYSPDEHPMVEMDHGIEMV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*: :**** :***.****.**:**:****:**:*:*:***: :* .**: **:.** ***::***:..: ***:****:** *: ** . : * :: .: *******:************:** . :::::* .* . * :***:*.***::: . . *: *:********.:* :* .::*: *** .* *:******:*** * ::*:*::: : *.**::****.**:** *: **:*.. *** * ::.*::..:*****:: *: : . :* .*: :. . .: ", "identical_positions": 144, "similar_positions": 100, "identity": "46.3%" }, { "cls_id": "homologset.agr.MGI:2143920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXL0-1", "uniprot_id": "D3ZXL0_RAT", "id": "D3ZXL0-1", "name": "", "aln": "MLQGAKDKMSGPLASGTCSDLEEASDLKAPLSSRFREPLTHARFQELFGGAEQEPELPAEPCLPWLCRLRRRRASACSGPGAWRVLLARLPPLRWLPQYRWRAWLLGDAVAGITVGVVHVPQGMAFALLTSVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAVLSLMTGSVVER-----------------------VVPEPLAGNLSGIEREKLEAQRIG------------------AAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLVSQLPSLLGLSLPRQIGCFSLFKTLAAVLSALNQSSPAELTISALSLALLVPVKELN-VRFRDRLPTPIPGEVVMVLLATVLCFTSSLDSRYNVQVVGLLPGGFPQPLLPTLDDLPRILADSLPISLVTFAVSTSLASIYADKYSYTIDPNQELLAHGVSNLISSLFSCFPNSATLATTSLLVDAGGNTQLSGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQMFFQMQELPQLWHVSRVDFAVWMVTWVAVVTLNVDLGLAVGVVVSMVTVVCRTQRVKCLALGLAEGTE-LYRPIRESHKLLQVPGLCILSYPAPLYFATRGQFHRVLEWHLGLG-----------------ERTKPGSVPDKGAEP-----------------IRVVILDFSGVTFADAAGAREVVQLTR----RCQDDGICLLLAQCNDLVLKTLTRAGLLDSMTPEQLFVSVQDAAAHALERLKPTGPKICTVWV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5EBI0-1", "uniprot_id": "S2610_MOUSE", "id": "Q5EBI0-1", "name": "Solute carrier family 26 member 10", "aln": "--------MSGPLASGTCSDPEEVSDLKSPLSSRFREPLTHARFQELFGGAEPEPELPAEPCLPCLCRLRRRRASACSGPGAWRVLLARLPPLRWLPQYRWRAWLLGDAVAGVTVGVVHVPQGMAFALLTSVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAVLSLMTGSVVER-----------------------VVPEPLAGNLSGIEREQLEARRVG------------------AAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVIKALTSGAALHVLVSQLPSLLGLSLPRQIGCFSLFKTLAAVLSALSQSSPAEVTISALSLVLLVPVKELN-VRFRDRLLTPIPGEVVMVLLATVLCFTSSLDTRYNVQVVGPLPGGFPQPLLPTLDELPRILADSLPISLVTFAVSTSLASIYADKYSYTIEPNQELLAHGVSNLISSLFSCFPNSATLATTSLLVDAGGNTQLAGLFSCAVVLAALLWLRPFFYYLPKAVLACINISSMRQMFFQMQELPQLWHISHVDFAVWIVTWVAVVTLNVDLGLAVGVVVSMMTVVCRTQRVQCLELGLAEGTE-LYRPIRESRKLLQVPGLCILSYPAPLYFATRGQFHRILEWHLGLG-----------------ERIKPG------AEP-----------------VRVAILDFSGITFVDAAGAREVVQLTR----RCQDDGIYLLLAQCNALVLETLTRARLLDSVSPEQLFVSVQDAAAHALERLKPTGPKICTVWV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG04-1", "uniprot_id": "S2610_HUMAN", "id": "Q8NG04-1", "name": "Putative solute carrier family 26 member 10P", "aln": "--------------------------------------------------------------------MRLDLASLMSAP---KSLGS-----------AFKSWRLDKAPSPQHTFPSTSIPGMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVER-----------------------LVPEPLVGNLSGIEKEQLDAQRVG------------------VAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELN-VRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDF------------------------------------------------------------LLQVPGLCILSYPTPLYFGTRGQFRCNLEWHLGLGEG-------------EKETSKPDGPMVAVAEP-----------------VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLDRVTPDQLFVSVQDAAAYALGSLLRGSSTRSGSQEALGCGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQZ8-1", "uniprot_id": "A0A8M1QQZ8_DANRE", "id": "A0A8M1QQZ8-1", "name": "", "aln": "---------------------------MSASVAIYRNIYTEDRFRQTYGTEDQSGGR-------ERLRDRLAQRCSCSQVECVHLLHKRLPVCSWLPKYKLRKWLLGDIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTGHHVSTGTFAVLSLMTGSVVEQ-----------------------LVPIPLALNSSSPEAAEFEAQRIG------------------VASAVAFLSGIMMLCMCGLQLGFLSTYLSEPIVKAFTSAAAFHVTVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNLAELVISLLCLAVLVPVKEVN-SRFRERLRTPIPVEIITVIIATGITYAFSLDSKYDIQIVGHIPAGFPEPRLPALETVPEIAGDTVAITLVAYAVSVSLAMIYADKHGYSIDPNQELLAHGISNTVSSLFTCFPNSATLATTNILESAGGHTQLAGLFTSLVVLIVLLLIGPLFYFLPKAVLACINVTSLRQMFLQFQDLPELWRISKIDFMVWLVTWLSVVVLNVDLGLAIGMVFSMMTVVCRTQRASCSVLGRAANTE-IYRSINNHNKCYEVPGVKILTYNGPIYYGNRSFFKADMAQLLGLTPERIRSREKALKAIEKREREAISTVEQGVADSSFSSKNDLFTSEMAEGEVQAVLIDCSSVIFVDIAGARLFIQMCM----ECQKIGVRIYLANCNESVLKILTSSGLMNYMNPQHIFVTIHDAVVYIQQQREKPPETNTMVWV------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVM6-1", "uniprot_id": "Q9VVM6_DROME", "id": "Q9VVM6-1", "name": "", "aln": "---------MPSDKESPETKPLNNNNTNGNGGSVPSKPKIQPKYSIHRDVLTHEVVIKQTGYAARDKSIPSSLRNCWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKIPLTKVSSS-----NSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSK----ELKVRGARLLLASPVDRVYDTLVHS-MALSEGPFEIFPTLHDCVEYANACRTA----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. : . ***:.:*:.*.. *** :.***: * ::**.:*:* ****: *:**...*: .. ** *. ...: :. .*:::*: * : * * *:** **: ****:::.:*:.** ** :** .:**: :** *.*.:: *: :: : ::. .:. :. :..:: :*: *: .: *:* *:: *: .: : .: *::: ** :*.*:*:* ** * :*.: *::.*::*:::: *:. .*.*:.* : .***::* * .* :.. *:*:* :.:*: : : .:** :*::.*.:. :*: .*: : *:* **:.*** : : ::: :* * ::* :: : .:::: :** : *: * .: :.. *: : :** : . . . .:. ::* * : . * **.* . :: . : : **. * *. : * .:* :::*.. : ", "identical_positions": 125, "similar_positions": 205, "identity": "16.09%" }, { "cls_id": "homologset.agr.MGI:2143974", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV39-1", "uniprot_id": "B2GV39_RAT", "id": "B2GV39-1", "name": "", "aln": "---MRLRN-GTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDIYQREF-LALRDRLHAAEQESLKRSKELN--LVLEEIKRAVSERQ-------ALRDGEGNRTWGRLTEDPRLKPWNVS-----HRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDTQYTSAVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQ-----PSE-DWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFG-KHALRKEHVN-PPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERPGMAFSLLGLDRGSWAVLRLTGPLGVCRFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSATLRYPRSPDGYLQIGSFY-KGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q812F8-1", "uniprot_id": "MGT4B_MOUSE", "id": "Q812F8-1", "name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "aln": "---MRLRN-GTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDIYQREF-LALRDRLHAAEQESLKRSKELN--LVLEEIKRAVSERQ-------ALRDGEGNRTWGRLTEDPRLKPWNVS-----HRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDPQYTSAVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQ-----PSE-DWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFG-KHALRKEHVN-PPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLER----------------------------FFFRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSATLRYPRSPDGYLQIGSFY-KGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ53-1", "uniprot_id": "MGT4B_HUMAN", "id": "Q9UQ53-1", "name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "aln": "---MRLRN-GTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDVYQREF-LALRDRLHAAEQESLKRSKELN--LVLDEIKRAVSERQ-------ALRDGDGNRTWGRLTEDPRLKPWNGS-----HRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDSQYTSAVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQ-----PSE-DWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFG-KQALRKEHVN-PPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLER----------------------------FFFRSGNIEHPEDKLFNTSVEVLPFDNPQSDKEALQEGRTATLRYPRSPDGYLQIGSFY-KGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GMK0-1", "uniprot_id": "MGT4B_DANRE", "id": "Q6GMK0-1", "name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "aln": "---MRLRN-GTFLTVLLFGLCGLISLSWYTAFSNSKGNVVDIYQREF-LALRDRLHSAEQENLKRSKELN--LVLDEIKRAIAEKQ-------ALRD--INRTWSSLSDETKLKLWNVTS----SKNVLQLPSIFHHLPHLLAKESSLQPAVHIGQGRTGVSIVLGVPSVKREVHSYLTDTLSSLMTELSPAEKEDCVIVVFIAETDQQYANSVADNLKRLFPGEIQSGLLEIISPSVHFYPDFSHLKESFGDPKERVRWRTKQNLDYCFLMMYAQTKGNYYVQLEDDIVARPNYFTTMKNFALQQ-----PSE-EWMILEFSQLGFIGKMFKSLDLPLIVEFMLMFYKDKPIDWLLDHIMWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFG-KQTLHKGHAN-PLAEVTTSLKTYQHFTLEKAYLGEDFFWAFTPVAGDFIRIRFFTPVRVER----------------------------YFFRSGNIEHPGDKLFNTTVEVLPFDNIQSEKEALKEGREKTPKYQRTEDGFIRIGKFE-NGIAEGEVDASFGPLEALRLSVLTDSPVWVILSEIFIKKAE------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUH4-1", "uniprot_id": "Q9VUH4_DROME", "id": "Q9VUH4-1", "name": "", "aln": "MFKIRQRNCMLIVTALVLAPCIVILMVMGPELSTEQSLTQRLAECHMRLQYLESMYRARQEDVALLSQYLGQLQIVNVTGASAPPPPPPLPVVNLLDGLSPEARQLLRNASHISKGGSANGSMARSQNIRLPNAYHFLPHLLDDAGSLRPAYLQSKGRSDVSIVLGVPTVRREKQSYLLGTLHNLIENMNDEEQNETLIIVYIGETDMESVQLIARQIESSFDQHVESGLIDIIAPAPSYYPNFERLRITLNDPLERVKWRSKQNLDFAYLMAYAHSKGTFYVQLEDDILTKRQFITTMKKFALIKSALTKPDQPEWFVLDFCQLGFIGKMFKSAELPYLITYFQMFYNDKPVDWLLTYFIESKVCRTDKDQKHCNAEKAKYWQHFRKSLFQHIGTSSSLKGKVQKLKDKQFGSKVPQYYAHTHNPPALVKSNIAPYKNYLLQRAYRGESYFWGLLPQPGDLVQIIFERPTQLRH----------------------------YLFRSGNSEHPSDRFYNTTVELLPADT-------LSENSSVWSSYNTTTDGYLVVGSFDSMGVAEGLLDAKIGAIKELRLHVHSDSENWALLSEIELQEWGSDSKSEDNAAKPRYVGGS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ** ::* *:: * .: : . :* .:. . : : .: * : :: *.**.: .: * : ::. * : * * .: * : .::. . : : ::**. :*.***** . .**:** .:**:.**:*:*:*:*:** :*** .** .*: ::. *::: :*:* *.*** : .. :: ::: * .:.***:::*:*: :**:*.:*: ::.** ***:**:*****:.:** **::** :********::: ::::***:*** : *.: :*::*:*.*********** :*. :: :: ***.***:**** ::: ***..:** ***: :**: :*: *****:** *** **:******:** * . *.: * * *.:.: .*::: *::** *.:**.: * .**:::: * * ::.: ::***** *** *:::**:**:** *. *.*. * : **:: :*.* *:*** :*. :*.:: *** : :** *.:**** ::: ", "identical_positions": 206, "similar_positions": 196, "identity": "33.12%" }, { "cls_id": "homologset.agr.MGI:2143977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAP7-1", "uniprot_id": "A0A8I6AAP7_RAT", "id": "A0A8I6AAP7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MITAIKKQNILHNPKEKADWFGMFDGYDS------CSEDTSSSSSSEESEEEAAPLPANLPIIKN------NGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSR------------------SYSSNSKKASILARLQGKPPTKKAKVLQ-----------------KQPLVAKLAAYAQYQAT----LQNQAKTKAGNSAISVEG----------------------------------------------------------------------------FSWGNYINSNSFIAAPVACFKHAPMGTCWGDISENVRIEVPNTDCS--------LPTKVFWIAGIIKLAGYNALLRYEGFENDSSLDFWCNICGSDIHPVGWCAASGKPLVPPRTVQHKYTNWKAFLVKRLTGAKTLPPDFPQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSD--ITKKQDG--------HFDTPPHLFAKVKEVDQ-----SGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSE-AADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRESQSASSKQKKKAKSQQYKGHKKKRK------MPVGKKPVSLSSLPMTGGVRRSFSGDEELTPPPYRTLPAQTALEAFPPPSTSREFR---PSLNTVTASQLKEELLDGEE--------YSFLHGASDQESNGSATVYIK-------QEP-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5G3-1", "uniprot_id": "MBTD1_MOUSE", "id": "Q6P5G3-1", "name": "MBT domain-containing protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDGYDS------CSEDTSSSSSSEESEEEVAPLPSNLPIIKN------NGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSR------------------SYSSNSKKASILARLQGKPPTKKAKVLQ-----------------KQPLVAKLAAYAQYQAT----LQNQAKTKAGNSAISVEG----------------------------------------------------------------------------FSWGNYINSNSFIAAPVACFKHAPMGTCWGDISENVRIEVPNTDCS--------LPTKVFWIAGIIKLAGYNALLRYEGFENDSSLDFWCNICGSDIHPVGWCAASGKPLVPPRTVQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSD--ITKKQDG--------HFDTPPHLFAKVKEVDQ-----SGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSE-AADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRESQSASSKQKKKAKSQQYKGHKK-------------------------------------------------------------------------MTTSQLKEELLDGED--------YSFLHGASDQESNGSATVYIK-------QEP-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05BQ5-1", "uniprot_id": "MBTD1_HUMAN", "id": "Q05BQ5-1", "name": "MBT domain-containing protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDGYDS------CSEDTSSSSSSEESEEEVAPLPSNLPIIKN------NGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSR------------------SYSSNSKKASILARLQGKPPTKKAKVLQ-----------------KQPLVAKLAAYAQYQAT----LQNQAKTKA---AVSMEG----------------------------------------------------------------------------FSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCS--------LPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSD--ITKKQDG--------HFDTPPHLFAKVKEVDQ-----SGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSE-AADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKK-------------------------------------------------------------------------MTTLQLKEELLDGED--------YNFLQGASDQESNGSANFYIK-------QEP-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGV5-1", "uniprot_id": "A0A8M2BGV5_DANRE", "id": "A0A8M2BGV5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENPRDMAEHTPRSERKRRDSFGMFDGYDS------CSEDSSSSSSSEDSEDEVPSIPASLPIIKN------NGQVYTYPDGKAGMATCEMCGMVGVRDAFYSKTKRFCSVSCSR------------------SYSSNSKKASILARLQGKPPTKKAKVLQ-----------------KQPLMAKLAAYAQYQAS----QQNQAKSKS---VVPVEG----------------------------------------------------------------------------FDWGQYICSNNLVGAPVSCFKHVPMGMCWGDIAEGLRVEVFNSDTN--------LSTKVYWVAEIVKLAGFKALLRYEGFDNDSSRDFWCNLCIPEIHPVGWCASSGKPLVPPKSIQHKYSNWKAFLVKRLTGAKTLPPEFATKVQENMQYPFKKLMRVEVVDKTHLCRTRVALVEQVIGGRLRLVYEESQDGTDDFWCHMLSPLIHSIGWSRSIGHRFKRSE--VSKKIEG--------QMDAPSQLFLKIKDVDQ-----NGDWFKDGMKLEAIDPLNLSAICVATVRKVLADGYLMIGIDGSE-AADGSDWFCYHSTSPSIFPVGFCEINSIELTPPRGCTKLPFKWFDYLREIGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLVCVATVTRIVHRLLRIHFDGWEDEYDQWVDCESPDLYPIGWCQLTGYQLQPPAAQTTREAPPNVSKQKK--KAAQYKGQKKKRK------IPVGRRPIGLGG----PLRRRSFSGDEEQTPPHYLSHFSGSR----RPPASGVERD---RSLNSEASLQVKEETPEIDE--------FTFSQGISDQESNGSGSYYIR-------QEP-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK33-1", "uniprot_id": "SMBT_DROME", "id": "Q9VK33-1", "name": "Polycomb protein Sfmbt", "aln": "MNPSELRMMWMSSQYNSERITLEDAATLLGHPTVGLSVMEDLSAHQPTLDMNPMMSLMGGDFTGQAAATAAALGVQPGTLIATNSNNLYGFAHMGGLQQQLLQQSAAAAVFQNYAEAMDNDVENGMVGMAMEAVVDDDDQVYGQRDNNFDDNGSELEPKQEIINIDDFVMMNEDNNSYDGTDFMTSSDKDISQSSSSCMAQMPGSLGVPGVEHDLLVPLPDGLLHHKLLGTTLVPAMGTLNGNAFGNIMVSTENTSSKQMQRTYSTAKGANSTATTATCSASTSSALRSQRKTRKIEPVNRPGLVLKTPIAYRGNIDPSVIPIQKDGMAVCKRCGAIGVKHTFYTKSRRFCSMACARGELYSLVLNTKMEGDQATTSSPDPGAGSESADLPGDQQQSQSDIELDLHAAHIKNANYRFRITDQSKITQLNSFGEPMSMGGDAAANNVQMAADETIAALNGGAVGDATAPGSTEEGASTPNSYLSAAPTPKALRLFKDIYPQDDLPQIPKYERLPVPCPQMEKIISIRRRMYDPTHSYDWLPRLSKENFNAAPVTCFPHAPGCEVWDNLGVGMKVEVENTDCDSIEVIQPGQTPTSFWVATILEIKGYKALMSYEGFDTDS-HDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVGRLSGARTLPSNFYNKINDSLQSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLRYFDSDD---GFWCHEDSPIIHPVGWATTVGHNLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYYSDGKTNSFVEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSDWFCYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLFHRIIPDHGFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVNHKLEGPPRVAHQQAPKPAPKPKIQRKRKPKKGAAGGKTPTDNNTQSVKSRTIALKTTPHLPKLSIKLELKPEHHNAAFYENNQPEEEGDEEDPDADGDGDGSTSHISEQSTTQSSSDLIAGSGSGSGSASLVTLATGSNKTNSSATNNKYIPRLADIDSSEPHLELVPDTWNVYDVSQFLRVNDCTAHCDTFSRNKIDGKRLLQLTKDDIMPLLGMKVGPALKISDLIAQLKCKVNPGRARSHKTNKSPFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :* ** .:**: *: . : .: ::*. * : . * * ***.*: ** :**:.:**:*::****::*:* : *.:. .* * * *. .::.: .*. :::* ::.: : *:.: : .::* :.* : .:.: .***:** *.* *.::. .:::** *:* . ... :*:* *::: *::**: ****:.** *** *:* .::*.*****: ****:**::::***.:** *** **:**:***.:* *:.:.:* *: :.:* *** ::.:.*:* * .::* ** * * :*:* .**** **:** :**: ::**.: .: : : * . *:. .** .*: . : * :******:******:** **: ** *::** **. : *.******** .**.***.***.:* *.:***.* . .*.* .***: *::** :**:: :*:***.***.**..***:***:*****:*:: ***::***** :*****:****.*:**:*** *..::*: *. : :: .* * * ** :: * ..: . .: * .. :*..: . ** .** ", "identical_positions": 245, "similar_positions": 216, "identity": "20.02%" }, { "cls_id": "homologset.agr.MGI:2143990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZ20-1", "uniprot_id": "PAR12_MOUSE", "id": "Q8BZ20-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "---MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTS--LGTDALERLLRDCGRFVVASRAVVAVGAGREAAAAASERLVLAVSSLRLCRAHQGPKPGCTGLCAQLHLCKFLIYGNCKFLKTGKNCRNGHNLKTDHNLSVLRTHGVDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGPFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSESLEQLERLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSPSPAGPQGSSERKDSSGPVSPGTPSQEESEQICLYHIRKSCSFQEKCHRVHFHLPYRWQFL--DGGKWKDLDNMELIEEAYSNPSKDRIVYTESAAGFHFDNLDFNSMKFGNTLARRLSTASSVTKPPHFILTTDWIWYWMDEFGSWQEYGRQGSGHPVTTISSSDVERAYLAFCAPGADAQAATLKFQAGKHNYELHFKAFLQKNLVYGTIRKVCRRPKYVSPQDVQMKQ----SCNTKLHGPKSIPDYWDPAALPDLGFKKITLSSSSEEYQKVWNIFNRTLPFYFVQKIERIQNMGLWEVYQWQKCQMQKQNGGKEVDERQLFHGTSANFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKS-DTHSHMMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSSKPPASPSIFVALGNLFTSRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3V3-1", "uniprot_id": "D4A3V3_RAT", "id": "D4A3V3-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "---MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTS--LGADALERLLRDRGRFVVASREGTGPAT---AAAAASERVVVAVSSLRLCRAHQGPKQGCTGLCAQLHLCKFLIYGNCKFLRTGKNCRNGHNLKTDHNLSVLRTHGIDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGHFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSENLEKLEKLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSSSPAGPQGTSERKDSS--VSPGTLSQEESEQICLYHIRKSCSFQDKCHRVHFHLPYRWQFL--DGGEWKDLDNMELIENAYCNPSKDRIVYTESAAGFHFDNLDFNSMKLGHTLARRLSTASSVTKPPHFILTTEWAWYWMDEFGSWQEYGRQGTGHPVTTISSSDVEKAYLSFCVPGADAQAAILKFQAGKHNYELDFKAFLQKNLVYGTVRKVCRRPKYVSPQDVQMKQ----SCNTKLHGTKSIPDYWDPAALPDLGFKRITLSSSSEEYQKVWNLFNRTLPFYFVQKIERIQNLGLWEVYQWQKGQMQKQNGGKEVDERQLFHGTSTNFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKS-DTHSHTMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSSKPPAGPSIFVALGNLFTSRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0J9-1", "uniprot_id": "PAR12_HUMAN", "id": "Q9H0J9-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "---MAQAG-VVGEVTQVLCAAGGALELPELRRRLRMG--LSADALERLLRQRGRFVVAVRAG--------GAAAAPERVVLAASPLRLCRAHQGSKPGCVGLCAQLHLCRFMVYGACKFLRAGKNCRNSHSLTTEHNLSVLRTHGVDHLSYNELCQLLFQNDPWLLPEICQHYNKGDGPHGSCAFQKQCIKLHICQYFLQGECKFGTSCKRSHDFSNSENLEKLEKLGMSSDLVSRLPTIYRNAHDIKNKSSAPSRVPP-LFVPQGTSERKDSSGSVSPNTLSQEEGDQICLYHIRKSCSFQDKCHRVHFHLPYRWQFL--DRGKWEDLDNMELIEEAYCNPKIERILCSESASTFHSHCLNFNAMTYGATQARRLSTASSVTKPPHFILTTDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDVEKAYLAYCTPGSDGQAATLKFQAGKHNYELDFKAFVQKNLVYGTTKKVCRRPKYVSPQDVTTMQ----TCNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKS-DTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYTTSSKPSVTPSILLALGSLFSSRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUY0-1", "uniprot_id": "Q1LUY0_DANRE", "id": "Q1LUY0-1", "name": "", "aln": "------MNIVSRHIYNFVCKQEGSSDYGKVEINLRKSFTVADQVLSMVLDDSQKFVIVHNDENPNPR---SSIPAADSLILAKTSLRVCKHDK-----CSG-CEDLHLCRYFVCGSCRFEG---KCKNSHDLKSAHNSDLLKKNDLLELTSEELFQLLLQNDPSLLPEVCFHYNKGNGDFGSCKYKTSCTNLHLCQHFLQEDCKFGATCKRAHKFDAS-ALKILSARGLSAENMRRLLKLYKNRLLIASAAFKKKETVSVPAAKGRTRHK-------SGNSVSEADHNEICLFFIRTGCSFKDKCARIHHNLPYKWQILQKDGTTWSDLPNEEEIEKAYCSPAN--VLCITDSSTGHMV-VDFMSMTCGVSDVRRLSTASSVTKPPHFILTTEWIWFWRNDKGGWTEYGKGEDAKLVASVTSEDLEKLYLADSE-------KEISFTSQNHQYVLKFKEMCQQNLKYKTERDVRRRPRFVSAQDVKSKIKGGDSTESSASSSADVPSYWDKGAPDTGTYKIVSLQKTCKEYERVSSMFNRTLPGSIIHRIDRVQNPSLWKVFEWQKEQMNLKSGGKVVDQRYLFHGTDESHMDAICDQNFDWRICGSNGTLYGKGSYFARDASYSDRYARSRNGKTKKMFMALVLVGDFIRGNNSLVRPPQKP-HSQRFYDSCVDNEANPAIFVVFEKFQIYPEYIIEYS-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LVS6-1", "uniprot_id": "Q1LVS6_DANRE", "id": "Q1LVS6-1", "name": "", "aln": "MSDMSDCTRVIHYATSILCSNKGSMEMSQLHRRVFQRFEISEADFWYIVKKCARFVMVQSRPG-------EEDAESDCTVVAKTSLRLCKKYSKNE---CYECQDLHLCKYFVYGNCRYGKGRKECKFSHNIQSQHNYPLLRECTLHELNEDDLFLLLLQNDPALLPEVCAHYNKGTGVFGACTFMERCTKVHICQHFVHDTCLFGPKCKRQHSIDGY-SRRMLEERGLSGDIIRELPYIYQNVYRLNSQPQSSELISDQGIKP-----------------VAQMEKNEICLHFIRRKCKFQDQCVLVHFNLPYKWELY--DGKGWRELRNMEDIERAYCDPKNE---YSPGSRP-----VNFVSMTKNGDPVRRLSTVSSVSKPAHYFLTTQWIWYYKGDHENWIEYGHPDDKQRATSVTSRELEKSFQEDNN-------AEVTVIKGNRHYYVSFQDMYQRNPKHNTKRRVRRRPRFVSISEVESKA-----------------------AQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:* *: : ::. .: :. : :: . :**:. . .: ::* :.**:*: . * :****:::: * *:: :*: .*.: : ** :*: : .*. :* **:**** ***::* ***** * .*:* : * ::*:**:*:: * **..*** *.: . *. *:*.: : .* *:* : . . :: : ::***..** *.*:::* :*.:***:*:: * * :* * * **.**..* .: ::* :*. . .*****.***:**.*::***:* *:: .: .* ***: : .::::* ::*: : :.. :::* : *: : *:* : * : * ***::** .:* * ", "identical_positions": 118, "similar_positions": 143, "identity": "16.32%" }, { "cls_id": "homologset.agr.MGI:2143991", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNS8-1", "uniprot_id": "EPOP_MOUSE", "id": "Q7TNS8-1", "name": "Elongin BC and Polycomb repressive complex 2-associated protein", "aln": "METLCPPPRLAVPASPRGSPCSPTPLKPRRGTPEFSPLCLRALAFCALAKPRPSSLGLGPGELAPRTPVLLGPPASPCTGGWAADGLKHLGGQAGRPSDVSSPAREDADVAVCPGGGEEEEGGGGFPHFGAGSCAPPGRCPAPLRPQDSPTNPAWSPPRPARG----LDAASSPPLEPGSPPPSPPAGLSPEPA-PSEQP---VPASEAPGGGDPAPTAPEAPALSPSTADAAPDPPRDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPAAK--ARGAAKKRRRPAPPPPSVQPRRPVPTLPTSSTFSLLDCFPCPPALVVEENGDLGPASSLRLQGDAKPPPAHPLWKWQMGGPAVPEPPGLKSWWVNLEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RD31-1", "uniprot_id": "M0RD31_RAT", "id": "M0RD31-1", "name": "", "aln": "METLCPPPRLAVPASPRGSPCSPTPRKPRRGTPEFSPLCLRALAFCALAKPRPSSLGLGPGELAPRTPVLLGSRASPCTGGWAADGLKHLGAQAGRPSDVSSATREDADVAVCPDRGEEEEGGGGFPHFGSGSCTPPGRCPA--GPRESPTSPARSPPRPARGLESQLDAASSPPLGSSSRPPSPPAGLSPEPA-PTEQP---MRDSEAPEGGDPARVAPEAPALSPSTADATPDAPGDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPAAK--ARGAAKKRRRPAPPPRSVQPRRPAPTLPTSSTFHLLDCFPCPPALVVEENGDLGPASSLRLQGDAKPPPAHPLWKWQMGGPAVPEPPGLKSWWVNLEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NHQ4-1", "uniprot_id": "EPOP_HUMAN", "id": "A6NHQ4-1", "name": "Elongin BC and Polycomb repressive complex 2-associated protein", "aln": "METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPGLKFWGINMDES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.****************** ** *** *******************.**** ******.*:*** *. *. .****.****** . :***. .:.: ******.** ************** **:******* *::*.*. * :***** * ..*:*** ..* *********.*** * * : . * .*:*. .****** *****..:* .* *******:*****************************.** ********* ***** :.*****.*****:*** **:********** *:*** **********:*********:*************** * :*::* ", "identical_positions": 271, "similar_positions": 51, "identity": "71.5%" }, { "cls_id": "homologset.agr.MGI:2143994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9R9-1", "uniprot_id": "A0A0G2K9R9_RAT", "id": "A0A0G2K9R9-1", "name": "Proteasome activator complex subunit 4", "aln": "----------------------MEAPERAGGGEPPEPGGRPVLGPRAFVPQK------------------------------------------------------------------EIVYNKLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDMVERILYSKTEHLRLNSFPN-------------------SIENVLKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAVSYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYP--ALETLTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNE----EELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSE--YFPIKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLQSFLQPELIKLQRCGDG-ELEMSRDDILQSLTIVHNCLIGSGNLLPP--------------------LKGEPVTNLVPSMVSLEETKLYTGLEHD------------------------------LSKENHREVIASVIRKLLS--HILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADAVRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPAT---------VLAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHE----STQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIP------------EFTARVLEKLKPLTDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIIRLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQSHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SSW2-1", "uniprot_id": "PSME4_MOUSE", "id": "Q5SSW2-1", "name": "Proteasome activator complex subunit 4", "aln": "----------------------MEAPERAGGGEPPEPGGRPVLGPRAFVPQK------------------------------------------------------------------EIVYNKLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDLVERILYSKTEHLRLNSFPN-------------------SIENVLKTLVKSCRPYFPADSTAEMLEEWRPLMCPFDVTMQKAISYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYP--ALETLTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNE----EELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSE--YFPVKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELIKLQCCGDG-ELEMSRDDILQSLTIVHSCLIGSGNLLPP--------------------LKGEAVTNLVPSMVSLEETKLYTGLEHD------------------------------LSRENYREVIASVIRKLLS--HILDNSEDDTKSLFLIIKIIGDLLHFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADALRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPTK---------ILAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMIEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHE----STQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIP------------EFTARVLEKLKPLTDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIICLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14997-1", "uniprot_id": "PSME4_HUMAN", "id": "Q14997-1", "name": "Proteasome activator complex subunit 4", "aln": "----------------------MEPAERAGVGEPPEPGGRPEPGPRGFVPQK------------------------------------------------------------------EIVYNKLLPYAERLDAESDLQLAQIKCNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTEHLGLNWFPN-------------------SVENILKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYP--ALETLTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKEIFMVALQKVFNFSTSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMNDDVLND----EELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFDKPPSE--YFPIKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELVKLQHCGDG-KLEMSRDDILQSLTIVHNCLIGSGNLLPP--------------------LKGEPVTNLVPSMVSLEETKLYTGLEYD------------------------------LSRENHREVIATVIRKLLN--HILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADALRNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQ---------IIAGDRPDNHWLHYDSKTIPRTKKEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKFVEQLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHE----STQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNITVETYNDWGACIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTTPTISPHVP------------EFTARILEKLKPLMDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IAF6-1", "uniprot_id": "A0A0R4IAF6_DANRE", "id": "A0A0R4IAF6-1", "name": "", "aln": "--------------MTVSNIIEVEEPELENCNVKMKKEASELLG---FSPQK------------------------------------------------------------------DIVYNELLPYKDKLDDESNEILAQIKGNLGRAVQLREVWPGVLFWTR----------------------------------------------KLSTYIRLYGRKFNKE-------------------------------------DHVLFVKLLYELVTIPKLEISMMQSFARLLITLLKKKELLSREDLELPWRPLYELQDRILYSKTEHLGLNWFPSSLRPRSSSKHIIVKLAQRCSVEAVLKVLIKSCRPYFPESATQEMLDEWKPLMCPFDVTMQKAMGYFELFLPTTLPPELHDKGFKLWFDDLISLWVSVQNLPSWEVNLVSLFARLANDNIGYIDWDPYIPKIFTRILRSLNLPVGSSQMLVSRYLTNAYDIS--------YVVIWISALLGGPSKQAQTQLSGLFNGITSFFHPSNHGRWLMKLMKLLQRLPASVVKRLHRERYRTPTWLTPIPESHLLSEQDITDFVESIKQPVLLAMFSKTG--SLDAAQALQNLALLRPELVIPPVLEKTYP--AMETLIEPHQLTATLSCMIGVARSLVAGGQRFPEGPKHMLPLLMRALPGVDPNDFSKCMITFQFLATFVTLVPLVDCSSAIHSRNGLTQVEKELCSASAEFEHFVLQFVDRCFALIDTSTLEQTREEMEMEKMTHLESLVELGLSSTFSTILTQCSMEIFQVALDKVFNFATTSIFETHVAG----------RMVADMCRATTKCHPAEALKLFLPHCCSAILQIAANEEVLNE----EELDKELMWNLQLLSEVVRVDGDQLLLYRSQLVQILQLTLHLKCKQGYSLACKLLYHILRSMSLIYPREYCSIPGGIQQHTDT--YLPIQDWGRPGELWNLEIQWHVPSTEETEFVFYLLDLLLKPELQRLQKHTEG-QQDISRDDVLQSLSIVHNCFLGASSLLPP--------------------LHGEPVPQLINGMVQLYETKVYTGVDYD------------------------------MSRENYREDICKVIRPLLN--HTLEHSEDDIKSLFSIIKIINDLLHFKGSHKNEFDTR----------------WKSFNLIKKSMEN-------RLHGSKQHIRALLIDRVMLQHELRNLTMEGCSYRS----VHQDLINDLLRLSTSRYSQVRCRAQNVLFTALGTYNFCCRDIIPVVLKYLDPERTDVTQQQFKGALYCLLGNHSGIC---------LANLQYWDCIALTWPALVRSGMSPSMSLEKTSIVRLFDDLADKIHR-----------QYETISVNFSIPESCVEIAVKMLKSSSPEPNPGAASEQEELEGRKREEQKNKDAMQKYEKLVADLLDCLHDRNIPWKFEQLTIGFLSLMLRDDLPLP-SSAVLFFVESLNHDSLLVRNVAISAVAGILKQLKRPHKKVAVSPYDISELKTSLQSRDGKAVVSLLTGDRPDNQWLQYDSSRLPRSQRDWDECCFIEKTHWGYSTWPRKLMLYAPLEEQPKQGQTREEMNEREQIIYDHFSDQLFIDQFIQYLSLEDRKGKDKFSPRRFCLFKGLFRNFDDAFLPLLKPHMERLVADSHE----SPQRCVAEIISGLIRGSKHWSYSKVEK----LWALLCPLLRKALSNITIETYIDWGTCIATACESRDPRKLHWLFEMLMESPVTGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLQYLEPKLTQVYKNVRERIGSVLTYIFMIDVDLPYTQPTTSPRIR------------EFTERVLARLKPLTEGEEEIQNHIVEENMEGDQDERTQAIKLLKTVLKWLMTSAGRSFSSSVPEQLRLLPLLFKIAPVENDDSYDEMKTDAKTCLSLMSQGLLYSDQIPQVLSALEEISRSSSWHARYTILTYLQIMVFYNLFTFLSDAKAVCDVRALVLRLLEDEQLEVREMAATTLSGFLQCNFLSIDEPMQAHFESLSKTRLPKRKRRELGSVVDTIPSADLVRRHAGVLGLSACILSSP--YDVPTWMPQILMDLSAHLNDTQPIEMTVKKTLSDFRRTHHDNWQEHKQKFTDDQLLVLTDLLVSPCYYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AA52Z1E4-1", "uniprot_id": "A0AA52Z1E4_DANRE", "id": "A0AA52Z1E4-1", "name": "", "aln": "----------------------------------MKKEQAEILG---FVPQK------------------------------------------------------------------EIVYNKLLPYADQLDRESNDILAQIKGNLGRAVQLRELWPGVLFWTR----------------------------------------------KLSTYLRLYGRKFSKE-------------------------------------DHVLFIKLLYELVTIPKLEISMMQSFARLLVNLLKKKELLSRDDLELPWRPLYDLYESILYSKTEHLGLNWFPN-YRAEASTKQKMLNIVRKRSVENVLKTLVKSCRVYFPESATQEMLDEWRPLLCPFDVTMQKAIGYFELFLPTIMPPEQHDKGFKLWFDEMMNLWVSVQNLPAWEGNLVNLFARLANDNIGYVNWDPYIPKIFTRILRSFNLPVGTSQMVVPRYLTNSYDIG--------HVVLWISSMLGGPQNQSQKQLNGLFSSIASFYHPSNNGRWLMKLMKLLQRLPASIVRRLHRERYKKPCWITPVPSTHKLTDQDVTDFVESMKQPVLMAMFSKTG--SMDAAQALQNLALMRPELVIPPVLEKTYP--AMETLTEPHQLTATLSCMIGMARSLLSGGRHYPEGPAHVLPLLMRALPGVDPNDFSKCMITFQFIATFTTLVPLVDCSSALHDKNDLTEMERELCSASAEFEDFVLQFMDRCFALIDSSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSMEIFKVALEKVFNFATTNIFETRVAG----------RMVADMCRAASKCHPAESLRLFVPHCCNAITHLTANEDVSNE----EELDKELLWNLQLLSEVTRVDGEKLLPYRTQLVQILQLTLRLRCKQGYSLACNLLHHVLRSTALIYPTDYCSVPGGFSRPLQE--YLPIKDWGRPGDLWNLEIQWHVPSTEETAFVFYVLDLLLQPELQRLQRYAQG-EQEMSRDDVLQSLCIVQHCLLGAGSMLPP--------------------LDGSTVTGLVPSMVNLEETKLYIGVDYD------------------------------QSRENYREAVCKVMRQLLH--YILEHSEDDTKSLFAIIKIISDLMHFKGSHKHEFDSR----------------WKSFTLVKKSMEN-------RLHGKKQHIRALLIDRVLLQHEMRKLLVEGCEYKT----VHQDLLRDLLRLSTSTYSQVRSKAQNVLFTALGTYNFCCRDITPRVLEFLEPTRTDVTQQQFKGALYCLLGNHCGVC---------LANLHDWDCIAQTWPAIVRSGLSSAMSLEKPSIVRLFDDLADKVHR-----------QYETIGIDFTVPENAVFLGRSITNSSQPTPHMSTPEDQELQQGLAVQQAKNREAEQKYEKLVKDLLECLDDRDLPWKFEHIAIGFLSLLLRDDYPLP-APAVFFFVQSLNHDALVVRKMAIAAVAGILKQLKRPRKKIPVNPCDISGVTEPEE---------LEAGDRPGNDWLQYHSESLPNSQQDWDAFCFVEKTHWGYYSWPKKLMVYAPAAEQPKD-LAPDTMSEREAIINDHFTDPMFINQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNYSDAFLPVLKPHMERLANDSHE----STQRCVAEIIAGLIRGSKHWSFGKVEA----LWAFLIPLMRTALSNITVETYADWGTCVATACESRDPRKLHWLLEMLMECPLSGEGGSFVDACHLYVLQGGLAQQEWRVPELLHRLLSYLEPKLTQVYKNVRERIGSVLTYIFMIDVALPYTLPTKSPHIA------------EFTERILTQLKPLIEGDEEIQNHVVEENGVGEQDERTQAIKLLKTVLKWLMASAGRSFSTPVPQQLQLLPLLFKIAPVENDDSYDELKRDAKTCLSLMSQGLLYPEQIPMVLAVLHEIAGSSSWHARYSVLTYLQTMVFYNLFTILSSEQCVQGVRALVIRLLEDEQLEVREMAATTLSGFLQCNFLAMDSSMQTHFEALCKTRLPKKRKRDVGSVMDTIPSVDLVRRHAGVLGLSACILSSP--YDVPTWMPQLLMDLSAHLNDTQPIEMTVKKTLSNFRRTHHDNWLEHKQQFTDDQLVVLTDLLVSPCYYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43583-1", "uniprot_id": "BLM10_YEAST", "id": "P43583-1", "name": "Proteasome activator BLM10", "aln": "MTANNDDDIKSPIPITNKTLSQLKRFERSPGRPSSSQGEIKRKKSRLYAADGRPHSPLRARSATPTLQDQKLFNGMDSTSLLNERLQHYTLDYVSDRAQHMKNIYDPSSRWFSRSVRPEFPIEEFLPYKTESHEDQAKYLCHVLVNLYIAISSLDIQGLISISSKDLADLKKEVDDLALKTDLFRLSNNTAENDLLGNDIADYDDAEGLEDELDEYFDLAGPDFNATGKITAKSATIVNVNHWTNELKNCLHFDFPVALRKSLATVYYYLSLVQGQKVYRQMHVDMFERLVSLDDDRTNFTELLQKQGLLLDHQIMLNFLCEFLPYPDPDYARYELSS---------------KEDLQLFRLLLKHAHNAKPFFDKSKESLLVDTMNFLLS--SLAPSTMMAVMPIVTSVVPYHYHIHSKIIDYFPFCYSIWSSVSANVAIDTHMYDFVGSISKDVHNKILSSEHEKDVVGVEFGEFGIFTDDQMTFMFNRLQGHLRTDGQIHSYSRTVKPFVYAINGSKKDRFFEKLVSLAKAIETFIHPSNNGFWTKPNAKFVHAFIKSYHGRVKYEEDICARGVTNGICLTSFCHEEIVEIFLNIISLGSQNKNPDIANYYISCFAYLLELDPSNAYLIYDKILIDLYDTLADQFINSRHRIISSLKQFTRVIR-FIVMDKLYRVHITNVLSMLVSKLDMNDTNLTSNLINGIVSIAAFIPIQDLTGEDDYISFESDTLPLVQQHFYHIKCGESSKTFRVDDELLNNAFKASTTVFQSMLKVYVEKIFQLVDVDLEDSLVTKINQTTMILQESMDDKIFNYFASLLQRNFWSNDSFKEKDPNYELVTIPLAALVRRNNGLSKELVRTLLFHIKEQIKRGAGSVRSTSEIQQRDVKLVLYLTALNDVLRQCHESLLEYSDELITFMKYLYDNVTNPPLDVITSIVIHSALATLCTTEITDCRLFPEDSKIPEKDRWGGLQFDPRRFDKQHLSFQWHVPSSDEITLSISILESLSEYCINNVEELMKAPRHDSEYGDMIQKYVLVMTHTLSGSSLLFDPDFNKYRTQSNLSYREKLILLKNIRENNCDPQELDIDIEQIRSGKDDEDYIESKDIEAGLNAGVSDVVQLRDEFPDELIVDEEVVSEMPSGVNTPIAGTHGTDNSAMSSDLAFRDLDIYTCNYYFGNTTEEKLQNPQYLQVHRVRARIGHFFHKLYVFLSTNFENNTNMFQILLHGLKVWFTDLGQETVFNEDPNAFIDVDFLENVQSLSHVNEPFTRTNFAIRANSLHQSRVLLHSTNRKASKLENLLLVDIIQLATSLY-PDIYKPAQGTLVHCMKQLVGSYGVVINKIIPSLEKAIKDHDYMKIQVILNVLLIKKIHRKLMTDYKDIGRLIFLLIECCRVNELEIGMYADKILTDIVIGIKIPSSVCVISDQAFLPLAPPDGTINLQVEAVKLAKKKKREYYLSLLVDLQDKLLDKLD--NEKDMGWKIRMFILRFVTQIQSNLESKPDKRAVFSIISQISTKHPEIIHLVVKSLLSTCNKIIS----LSDYEYDITRAYKNEFN-----PSFVEILDTSTTSFPKTFTEEMNNFDN--PKYFIDLRAYVGWLCWGRLMYVMS-----PKALKLNLRENELEVLKTAGHLLTREFLRDVTMNLVQDNETRGVFSSGNVSFFSLVILLISSGFCELNMSDLFELCESYYNKDDKASMIMSVEIVAGLVCGSKFMSVSDLDKRDTFIENFLAKCLDYELNHDAFEIWSTLAWWLPAVVDLRRSKTFFCHFINADGMFDRESDAATHQTSKIYMLRSILMSMEFRAPDVGK---LFDELVFDHPYDQVRQAVAKLLTTLVQNQSNPSISDPTTLLEAERNDPDGLGLPLKSVPEKVDAYIKKQFEIIKNLEDSVVGLN--PQQFIKTDYFYRTSTIFYWIKEMARGPNKVLLVPYLVDYVLPFLIGLVKHKDVCALASLDPVRLYAGLGYMPIRKNHVAAIVDYVCSSNVALSSNQTKLQLAFIQHFLSAELLQLTE-EEKNKILEFVVSNLYNEQFVEVRVRAASILSDIVHN--WKEEQPLLSLIERFAKGLDVNKYTSKE----RQKLSKTDIKIHGNVLGLGAIISAFPYVFPLPPWIPKQLSNLSSWARTSGMTGQAAKNTISEFKKVRADTWKFDRASFNTEELEDLEGVLWRSYYA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: :::*** . . :. *.:: ** *:. :: : :: :*. *: * * .*. ::.*: ::.:.*:: :. * : .***.: .* * : : :: :* . :.. .: :* :..: :* . ::: . *:. .:: .. : : :. .. .. : :* .:* **. : :: .:.. ::.* . : . : .:. : .:.: .. . .: . * . . . :: :: *. .. :* .* ..* :* ****:* * *::: : * *:: *. . :* : .:::.::. : . .. . :.. * :* .. *: :* * * : : . *:: ::*. . : * :: .: : ::*.:*: * *.* *: : : :.:* .: *.. .. : ... : :: * :* : .: . :. : :: .**::.*..:: * :.* : : :*:**: .: : .. :. .:*: * : : .*. . :: . .. :: * :*: * *.:: * .** * :*: ::: : : .:: * : * : .: . : :: : : :* :******::* : : :*: : : : .:: .. . : . .*::*. :* :....:* *.. :.: :: * : : *: . : . :. : : ::* . . * :.* * .: :.:::. * : ::...:** *** * : * : *: :. : :: . ::: : . : : :. * * :.. * *: ** . . * :* : .: *:*.: : : : : * .:: . : : : .* **: * : : * :.:.:*.. :. . * . : . :. . . : : *: .:::: **:. : : ::: : : * *: ::..:. . : ::.: :: . ::: :. :*: : * . . : : :. : . .. : ::: *: * : : : : ** * * : . . : : ::*.: :. *.. ...:*. :: ...* : ..: .* . :: :. .**::**: ***. : .:: : :* : *.: :.* : . :.: : * .:.:. : ...: ::.::*:*:. * . *:*.*:: : : * : : *.:**: :..:** :. : . : ** ... :: :* : ::::: :: * :: :*: : .*:: *: * . . : * * * *. *::.: . *. : :. : .::. :: : . : * : *:::* :: :*: : . . :. :: * ::: :*** **: **.::: :..: :* :.* :: . * :: *..****.* : : * : :*.*:*: * :**: . . :.*:*:*:*::.: *.* .: .*. ::* * .:* . * ", "identical_positions": 228, "similar_positions": 676, "identity": "10.4%" }, { "cls_id": "homologset.agr.MGI:2144013", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80U96-1", "uniprot_id": "XPO1_RAT", "id": "Q80U96-1", "name": "Exportin-1", "aln": "-----------MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQ----YEEQFETLFTLTMMQLKQ-MLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHGQLLEKRLNLREALMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSASPLLSGSQ----------------HFDIPPRRQLYLTVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTEIIMTKKLQNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTPLNPG----SPVSNQMFIQDYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEERETALRQAQEEKHKLQMSVPGILNPHEIPEEMCD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5F9-1", "uniprot_id": "XPO1_MOUSE", "id": "Q6P5F9-1", "name": "Exportin-1", "aln": "-----------MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQ----YEEQFETLFTLTMMQLKQ-MLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHGQLLEKRLNLREALMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSASPLLSGSQ----------------HFDIPPRRQLYLTVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTEIIMTKKLQNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTPLNPG----NPVNNQMFIQDYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEERETALRQAQEEKHKLQMSVPGILNPHEIPEEMCD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14980-1", "uniprot_id": "XPO1_HUMAN", "id": "O14980-1", "name": "Exportin-1", "aln": "-----------MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQ----YEEQFVTLFTLTMMQLKQ-MLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSASPLLSGSQ----------------HFDVPPRRQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTSLNPG----NPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HRQ1-1", "uniprot_id": "A0AC58HRQ1_DANRE", "id": "A0AC58HRQ1-1", "name": "Exportin-1", "aln": "MAGVMIMSPSSMPAIMTMLADHAARQLLDFNQKLDINLLDNVVNCLYHGVGPQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYALQILETVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDAANVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMIILKLLSEEVFDFSSGQMTQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLVYKFLNVPMFRNVTLKCLTEIAGVSVSQ----YEEQFVNLFTLTMMQLKQ-MLPLNTNIRLAYANGKDDEQNFIQNLSLFLCTFLKEHGQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSTSPLLSGSQ----------------HFDVPPRRQLYLPVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYADTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQAVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQTNGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVGENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMATIVNKLGGHITGEIPQIFDAVFECTLNMINKDFEEYPEHRTHFFYLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILYTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTTLNPS----NPVNNQVFIQEYVANLLKSAFPHLQDAQVKVFVTGLFSLNQDIAAFKEHLRDFLVQIKEFAGEDTSDLFLEEREASLRQAQEEKHKLQMSVPGILNPHEIPEEMCD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F0E8-1", "uniprot_id": "E7F0E8_DANRE", "id": "E7F0E8-1", "name": "Exportin-1", "aln": "-----------MPADMTMLADHTARQLLDFSQKLDINLLDNVVNSMYYDVGSQQRLAQEVLTNLKDHPDAWTRVDTILEFSQNMKTKYYALQILETVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDANSVEKEQVYISKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMIILKLLSEEVFDFSSGQMTQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLVYKFLNVPMFRNVTLKCLTEIAGVSVSQ----YEEQFVNLFTLTMMQLKQ-MLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHGQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSTSPLLSTSQ----------------HFDVPPRRHLYLPVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYADTERIMTEKLHNQVNGTEWSWRNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQAVQERLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVRQLGSILKTNVRACKAVGHPFVLQLGRIYLDMLNVYKCLSENISSAIQSNGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVGENFVPPLLEAVLIDYQR-NVPAAREPEVLSTMATIVNKLGSHITGEIPKIFDAVFECTLEMINKNFEEFPEHRTHFFYLLQAVNSQCFPAFLSIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILFTMLQNIAQEEAA--AQSFYQTYFFDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISVALNAG----TAGNNQGYVQDYVANLLKTAFPHLQDAQVKVFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDSTDLFLEEREASLRQAQEEKHKIQLSVPGILNPHELPEEMCE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9TVM2-1", "uniprot_id": "XPO1_DROME", "id": "Q9TVM2-1", "name": "Exportin-1", "aln": "--------------MATMLTSDEAGKLLDFSQKLDINLLDKIVEVVYTAQGEQLRLAQSILTTLKEHPEAWTRVDSILEYSQNQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKLNMILVHILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQTKAKHLKDTMCSEFSQIFTLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIFETQQIETLIFKFLSVPMFRNVTLKCLSEIAGLTAAN----YDENFATLFKDTMVQLEQ-IVGQNMNMNHVFKHGSDTEQELVLNLAMFLCTFLKEHGKLVED-AKYVDYLNQALMYLVMISEVEDVEVFKICLEYWNSLVEDLYN------SEFFHPTLESTK----------------RQQVYPRRRFYAPILSKVRFIMISRMAKPEEVLVVENENGEVVREFMKDTNSINLYKNMRETLVFLTHLDSVDTDRIMTLKLLNQVNGSEFSWKNLNTLCWAIGSISGAFCEEDEKRFLVTVIKDLLGLCEQKKGKDNKAIIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAIKCRRYFVTIQPNEACTFIDEILTTMSSIICDLQPQQVHTFYEAVGYMISAQVDQVQQDVLIERYMQLPNQVWDDIISRASKNVDFLKNMTAVKQLGSILKTNVAACKALGHAYVIQLGRIYLDMLNVYKITSENIIQAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMDNFIPPLLDAILLDYQRCKVPSAREPKVLSAMAIIVHKLRQHITNEVPKIFDAVFECTLDMINKNFEDFPQHRLSFYELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMGLNILFKMLQNLDQHPGA--AQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYMFSLVENRKITVNLGP------IPDNMIFIQEYVASLLKSAFTHLSDNQVKVFVTGLFNLDENVQAFKEHLRDFLIQIREATGEDDSDLYLEEREAALAEEQSNKHQMQRNIPGMLNPHELPEDMQDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30822-1", "uniprot_id": "XPO1_YEAST", "id": "P30822-1", "name": "Exportin-1", "aln": "-----------------------MEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEVQRLPATEMSPLIQLSVGSQAISTGSGALNPEYMKRFPLKKHIYEEICSQLRLVIIENMVRPEEVLVVENDEGEIVREFVKESDTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLDLTVKKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMN-NVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQYKDLVVFKGTLRDFLVQIKEVGGDPTDYLFAEDKENALMEQNRLEREKAAKIGGLLKPSELDD-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***.:.*** ***::*. .* * * : **.:** ::::*:** :.* **::* * .:*: .*.**: :*. :**:**.:: **:::**.:**. ..* .: :: :.* :: **:***:***::* **.:::*:* :. .:* ***::** ********* *:**.*: ***::*..**.*** ** *:*:. .:.*: .***:***:*:*** **:**: :. * **:. * * ::****:*::.:. .: ..: :* *: *: :: . ::. .: :... :*.:: :*::** *:* .: *:*. . : * :* *:: :*::*: *:** *:**: *. :*: : * :. : . ::::* : ::*::::..*.:*********::**:****:*::::*:***. **.**:****: **: ** ** .*::*:*:**:*:***.********:: *: ****:********.* :*:******::**:***:********:***:**:**: **********:*************. **: :** * * .**: *: :.. .***********:* * :*. : . . :: *:. * *** .** *:.::: * :* : :*: :..*:**** .*.::* : ***:** :**::*: *. * : :* ..: * :: ::.:*:* *:*:. ::*::.: : * . :: ***:*:* ** . :** **:.:**. *: :*.*: *. : *:::******:****:* ::*:** *: **:.:* :.* *** :**: ***..*:: *****. *:* **:* :::*: : . *:.*::.** :: . * *:**:.*.:*:. :* :* ::.** : **:. * .* ::.:*:*.:*..**.** . *: *::.* . ::: .** *****:**:* *: *: *::* :* : : ::: .: *:::* *: : ", "identical_positions": 417, "similar_positions": 378, "identity": "37.47%" }, { "cls_id": "homologset.agr.MGI:2144023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GIW9-1", "uniprot_id": "A0A8I6GIW9_RAT", "id": "A0A8I6GIW9-1", "name": "", "aln": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVR-CLQNTSVMEDQNEDESPKKSALWQVGMISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGP-PNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SRY7-1", "uniprot_id": "FBW1B_MOUSE", "id": "Q5SRY7-1", "name": "F-box/WD repeat-containing protein 11", "aln": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVR-CLQ------------------------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGP-PNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKB1-1", "uniprot_id": "FBW1B_HUMAN", "id": "Q9UKB1-1", "name": "F-box/WD repeat-containing protein 11", "aln": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVR-CLQ------------------------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGP-PNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QFQ6-1", "uniprot_id": "FB11A_DANRE", "id": "A0A2R8QFQ6-1", "name": "F-box and WD repeat domain-containing 11-A", "aln": "MDPD--KEDKTLELMCSLPRSVWLGCSSVAESLCALRCLQSLPSSRAHNQNMTGMESQINTDEVSPKK---TTVFKLGNGSLAGSRKRPSQGSFDKEKDLCIQLFDQWSESDQVEFVEHLIARMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSFLDARSLCSAELVCREWQRVISDGMLWKKLIERMVRTDPLWKGLSERHQWEKYLFKNRTNEVP-PNSYYHSLYPKIIQDIETIEANWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKQSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVSSGEVLNTLIHHNEAVLHLRFCNGLMVTCSKDRSIAVWDMASATDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSSNGQSDGRSPS----RTYTYVSR---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8RWN9-1", "uniprot_id": "FB11B_DANRE", "id": "A0A2R8RWN9-1", "name": "F-box and WD repeat domain-containing 11-B", "aln": "--------------MFDLKQTLLL--------ISELMHLFLLR-----LQNTSVMDPQT--ADRSPK----ITLIKVSNGPLTGSRKRPSEGNYEKEKDVCIQLFDQWSEADQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPAQGLDHIAENILSFLDARSLCSAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERHQWEKYLFKNRTTEVP-PNSYYRSLYPKIIQDIETIEANWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHHNEAVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHK1-1", "uniprot_id": "A0A0B4KHK1_DROME", "id": "A0A0B4KHK1-1", "name": "", "aln": "--------------MMKMETDKIMDETNSNAQAFTTTMLYDP------------------------------------------VRKKDSSPTYQTERELCFQYFTQWSESGQVDFVEHLLSRMCHYQHGQINAYLKPMLQRDFITLLPIKGLDHIAENILSYLDAESLKSSELVCKEWLRVISEGMLWKKLIERKVRTDSLWRGLAERRNWMQYLFKPRPGQTQRPHSFHRELFPKIMNDIDSIENNWRTGRHMLRRINCRSENSKGVYCLQYDDGKIVSGLRDNTIKIWDRTDLQCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWDLVAALDPRAASNTLCLNTLVEHTGRVFRLQFDEFQIVSSSHDDTILIWDFLNFTPNENKTGRTPSPALMEHXHFVQRQLRELHLQSSSEGEEDDDADEDDEDDFEEEDSRNDAGAFMGGYVRHRDAGGSGSVTGSGSDPESDDLDFDIDVENINDYDE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : * **: *. .::.*:::*:: * ****:.**:*****::********:**:************ ** :***********:***.** ::****:** ****:********** ****.**:**:**: * :**** *. : *:*:::.*:***::**::** *** *** *:**:**************** **:******:*****: *:*:* * ************::**::************.:**::****** ******** **:***************:*.::*:******************:******************:*******************************:****************************.***************** *******.:.****.*****:*************:***************.... :. *:** . ::.* ", "identical_positions": 368, "similar_positions": 87, "identity": "56.36%" }, { "cls_id": "homologset.agr.MGI:2144041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54929-1", "uniprot_id": "WSB2_MOUSE", "id": "O54929-1", "name": "WD repeat and SOCS box-containing protein 2", "aln": "-------MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCVVKLVPWPLEEQFIPKGFEAKSRSSKNDPKGRGSLKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQAPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKS-VFLWSMRSYTLIRKLEG-HQSSVVSCDFSPDSALLVTASYDTS----VIMWDPYTGERLRSLHHTQLEPTMDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRIWALELKAPVAFAPMT--NGLCCTFFPHGGIIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYS7-1", "uniprot_id": "WSB2_HUMAN", "id": "Q9NYS7-1", "name": "WD repeat and SOCS box-containing protein 2", "aln": "-------MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCIVKLIPWPLEEQFIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKS-VFLWSMRSYTLIRKLEG-HQSSVVSCDFSPDSALLVTASYDTN----VIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMT--NGLCCTFFPHGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AQQ7-1", "uniprot_id": "A0A8I6AQQ7_RAT", "id": "A0A8I6AQQ7-1", "name": "WD repeat and SOCS box-containing protein 2", "aln": "-------RRPLEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCVVKLVPWPLEEQFIPKGFEAKSRSSKNDSKGRGSLKEKTLDCGQIVWGLAFSPWPSPPSRKLWLRHHPQVPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPNGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKS-VFLWSMRSYTLIRKLEG-HQSSVVSCDFSPDSALLVTASYDTS----VIMWDPYTGERLRSLHHTQLEAPVDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRIWALELKAPVAFAPMT--NGLCCTFFPHGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRRFLTTYQVLALPIPKKMKDFLTYRTL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8JKT2-1", "uniprot_id": "B8JKT2_DANRE", "id": "B8JKT2-1", "name": "", "aln": "MCAPPQAYNVKEPPELLAELKAAHRPRLYGTPDCETWSARFSPDGSYFAWSMGFGVIKLLPWPLTTRDS-----AESCCSK----------EKILNCRFLVWALAFGPCTS--TRVDSAHQHRREHEL---LLAAGLHNGSIQVWLVSTGNLQFTLTGHQAPVRDLVFAPNGSLTLISASRDKTLRIWDLGKKGASPHVLRGPNYWVFRCAVSPDSSVIASVCNLDSKVYLWSLRSYTFMKHLTYDHERTMASCDFSQDGALLAIASYHSNTGWWLDLWDPYTADLLTRVQDCEVCAYRSDN-----LLTSLSFSPVALLLA-FKDYRALQIWDVERDKLVADTDHNRAGGVCCAFHPQGGVIATGCRDGHVKFWKVPHLVPSLRHLCRVALRFSISTYQVEALPLPTKILEYLTYRDIPKQKILYCKEHGR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * ******..: :: ...*****. ******:**** *. ::**:**** : *:* .** ** *:* :**.***.* .* :* ::* : :: :**:**::*.*::* *.** * :.*:*** **** *:*.*** *:*************.*:* . :** * **: *::***.*::.*... .* *:***:****::::* *: ::.***** *.***. ***.:. : :*****.: * ::. :: . .*. * *:.*** .* ** . * * *:** :* . :* : . .*:**:*.*:**:**** *****:**..*:::.**:**** *** ::**** ***:*.*: ::**** : ", "identical_positions": 184, "similar_positions": 117, "identity": "42.59%" }, { "cls_id": "homologset.agr.MGI:2144047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVH0-1", "uniprot_id": "D3ZVH0_RAT", "id": "D3ZVH0-1", "name": "STE20-related kinase adapter protein beta", "aln": "MSLLDCFCASRTRVESLRPEKQSETSIHQYSVDEPAISWSPPCATTNEVLCSTDATHYELHVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLETCTDERLRALQRAVILSHFFQHPNITTYWTVFTVGSWLWVIYPFMAYGSASQLLRTYFPDGMSETLIRNILFGAVRGLNYLHQNGCIHRSFKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVFDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHSTQMLLQKLKGPPYSPLDVSIFPQSDSRMRNSQSGVDSGIGESVLVSTGTHTVNSDRLHTPSTRTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNRPAASLPPVSPWSELEFQFPDDKDPDWEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4T3-1", "uniprot_id": "STRAB_MOUSE", "id": "Q8K4T3-1", "name": "STE20-related kinase adapter protein beta", "aln": "MSLLDCFCASRTRVESLRPEKQSETSIHQYLVDESAISRPPPSARASEVICSTDVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTVKITNLESCTEERLKALQRAVILSHFFQHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPDGMSETLIRNILFGAVQGLNYLHQNGCIHRSFKASHILISGDGLVTLSGLSHLHSLLKHGQRHRAVFDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDVSIFPQSDSRMRNSQSGVDSGIGESVLVSTGTHTVNSDRLHTPSTKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILPLLPPAYNRPSASLQPVSPWSELEFQFPDDKDPVWEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0K7-1", "uniprot_id": "STRAB_HUMAN", "id": "Q9C0K7-1", "name": "STE20-related kinase adapter protein beta", "aln": "MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83098-1", "uniprot_id": "STRA_DROME", "id": "P83098-1", "name": "STE20-related kinase adapter protein stlk", "aln": "------------------------------------------------MMCSNNISDYKLLEILKN--GMIGTVYKAEDINNKCLAVKKVS--MDQPMEKLTLLFNEVLTVRRLQHRNINTIVSCFLYKQYVYLTYKFMCFGNCEVLLKNVYTSGFPEVAIALILKDVLSALTYIHSEHYVHGSVRAKHILLS-PRKAVLSNFSYCQSFISQGEKKTFIFGSTVGIEKELYWTAPEVLYQNLSGYTEKIDIYSIGITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSLSLEHT--NKRIARDVIVN----------------KSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQCRNTSLLDQLKDLGQKMSKFKRNEHEIFSDARGSHN-PQPNDTIWKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::**.: :.*:* : . . : :*: *.. . *.. *:: *:* * . *: : ::* **.* : * .:::: **.:*... **:. :..*:.*. * ** ..: .*.*:*.: :* *.:*.***:* ..**.:*: :*::.:*::: ::. . . * :**:* *:* **. * ****:***.**:*.* **:* . * * ::*::*. ** . : :.:. : .:: :. *...*:*. ::** *..:*:***:::* .* :**.*::* *:** :: * . * * .: . : . :. . : *: :*. *:*", "identical_positions": 97, "similar_positions": 140, "identity": "23.21%" }, { "cls_id": "homologset.agr.MGI:2144095", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R0F9-1", "uniprot_id": "S14L4_MOUSE", "id": "Q8R0F9-1", "name": "SEC14-like protein 4", "aln": "---------------------MRGQVGDLSPQQQEALARFRETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQQNLDQILTWQAPE---------VIQLYDSGGLSGYDYEGCPVWFDIIGTMDPKGLFMSASKQDMIRKRIKVCEMLLH-ECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQFFAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKRYYLSNQERPQYEHSVVVGRGSSHQVENEILFPGCVLRWQFASDGGDIGFGVFLKTRMGERQKAGEMVEVLPSQRYNAHMVPEDGSLNCLKAGVYVLRFDNTYSLLHTKKVGYTAEVLLPDKACEEKLQGLGSVSPP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDX3-1", "uniprot_id": "S14L4_HUMAN", "id": "Q9UDX3-1", "name": "SEC14-like protein 4", "aln": "---------------------MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQQDLDNIVTWQPPE---------VIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMIRKRIKVCELLLH-ECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGVYVLRFDNTYSRMHAKKLSYTVEVLLPDKASEETLQSLKAMRPSPTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33324-1", "uniprot_id": "YKJ1_YEAST", "id": "P33324-1", "name": "CRAL-TRIO domain-containing protein YKL091C", "aln": "MTTS----ILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKN-YKERLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGISLSNAYH-VLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFILGSSYKKELLKQIPIENLPVKYGGTSVLHNPN--------------DKFYYSDIG--PWRDPRYIG-------------------------------------------PEGEIPNIFGKFTVTS--------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24280-1", "uniprot_id": "SEC14_YEAST", "id": "P24280-1", "name": "SEC14 cytosolic factor", "aln": "MVTQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAG-FIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYD------EKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYS-VMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGKSEVDESK--------------GGLYLSDIG--PWRDPKYIG-------------------------------------------PEGEAPEAFSMK------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *:* *::** .:*. * : . ** ***:****:**:: : :*: . .:*:: . : *: : : . * :* *::*: :* :: : : :::: *::: : * . . :: * :* ::*::*:*: : .:. :: * : *** : :: :*.:* *.. *.:.*.*:. * **.***..:::** * :. ::***::**. : : * .: :... :* * : : ", "identical_positions": 60, "similar_positions": 101, "identity": "13.73%" }, { "cls_id": "homologset.agr.MGI:2144113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK13-1", "uniprot_id": "VMA12_RAT", "id": "Q5BK13-1", "name": "Vacuolar ATPase assembly protein VMA12", "aln": "MASSLLAGERLVRALDPGGELEREQLPRKLRAQLEAALGKKHAGSDNATGPRRLVSFRLIRDLHQHLRERNSMLYLHELLEGSEIYFPEIVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDAQCGGTLSDLGKQVRSVKALVITIFNFIVTVAAAFVCTYLGSQYIFTEMASRVLAALIVASVVGLAELYVMVRAMEGELGEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SYH2-1", "uniprot_id": "VMA12_MOUSE", "id": "Q5SYH2-1", "name": "Vacuolar ATPase assembly protein VMA12", "aln": "MASSLLAGERLVRALGPGGELEREQLPRKLRAQLEAALGKKHAGSDNATGPRRLVSFRLIRDLHQHLRERNSRLYLHELLEGSDIYFPEIVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDAQCGGTLSDLGKQVRSVKALVVTIFNFIITVAAAFVCTYLGSQYVFTEMASRVLAALIVASVVGLAELYVMVRAMEGELGEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N511-1", "uniprot_id": "VMA12_HUMAN", "id": "Q8N511-1", "name": "Vacuolar ATPase assembly protein VMA12", "aln": "MASSLLAGERLVRALGPGGELEPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQVRSLKALVITIFNFIVTVVAAFVCTYLGSQYIFTEMASRVLAALIVASVVGLAELYVMVRAMEGELGEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************.****** *:*******:********* *.*.::**:******************:* **********:**:**:************************************:: *************:****:******:**.************:*************************************", "identical_positions": 185, "similar_positions": 19, "identity": "88.94%" }, { "cls_id": "homologset.agr.MGI:2144114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A6I8PU40-1", "uniprot_id": "TUG1_HUMAN", "id": "A0A6I8PU40-1", "name": "Taurine up-regulated 1 protein", "aln": "MARPPPLPGLVGRRNGRAVDRAIGWRLFLLLWHPALGAQARPPRRAPGGRWRSRRVFLLVRRTRAAAYAFAIRRGVVRVVGGGGQLLRPAPGEAAAAAAAGFGAAGEAGVAGAGLEAWRHPSGPARTQLGGQEGAGGWLVVGFLLCLFLLMPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6I8MX38-1", "uniprot_id": "TUG1_MOUSE", "id": "A0A6I8MX38-1", "name": "Taurine up-regulated 1 protein", "aln": "MARPPPLPGLVGRRSGRAVDRAIGWRLFLLLWHPALGAQARPPRRAPGGRWRSRRVFLLVRRTRAAAYAFAIRRGVVRVVGGGGQ-LRPAPGEAA----------GEAGVAGAGLEAWRHPSGPARTQLEGQEGAGGWLVVGFLLCLFLLMPP", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************.********************************************************************** ********* ************************ ***********************", "identical_positions": 140, "similar_positions": 1, "identity": "91.5%" } ]