{
  "uniprot": {
    "url": "http://www.uniprot.org/uniprot/P29460-1/",
    "uniprot_canonical_ac": "P29460-1",
    "uniprot_id": "IL12B_HUMAN",
    "uniprot_canonical_ac_length": "402"
  },
  "sequence": {
    "length": 640,
    "sequence": "MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLNLGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ"
  },
  "mass": {
    "chemical_mass": 638
  },
  "recommendedName": {
    "full": "Sex hormone-binding globulin",
    "short": "SHBG"
  },
  "alternativeNames": [
    {
      "full": "Sex hormone-binding globulin",
      "short": "SHBG"
    }
  ],
  "glycation": [
    {
      "residue": "T",
      "position": 36,
      "glytoucan_ac": "G123456",
      "type": "N-Glycan",
      "evidence": [
        {
          "database": "UniProt",
          "id": "P04278",
          "url": "http://glycomics.ccrc.uga.edu/ontologies"
        }
      ]
    },
    {
      "residue": "S",
      "position": 6,
      "glytoucan_ac": "G123456",
      "type": "N-Glycan",
      "evidence": [
        {
          "database": "UniProt",
          "id": "P04278",
          "url": "http://glycomics.ccrc.uga.edu/ontologies"
        }
      ]
    },
    {
      "residue": "N",
      "position": 136,
      "glytoucan_ac": "G123456",
      "type": "N-Glycan",
      "evidence": [
        {
          "database": "UniProt",
          "id": "P04278",
          "url": "http://glycomics.ccrc.uga.edu/ontologies"
        }
      ]
    }
  ],
  "glycosylation": [
    {
      "residue": "T",
      "position": 36,
      "glytoucan_ac": "G123456",
      "type": "N-Glycan",
      "evidence": [
        {
          "database": "UniProt",
          "id": "P04278",
          "url": "http://glycomics.ccrc.uga.edu/ontologies"
        }
      ]
    },
    {
      "residue": "T",
      "position": 294,
      "glytoucan_ac": "G123456",
      "type": "N-Glycan",
      "evidence": [
        {
          "database": "UniProt",
          "id": "P04278",
          "url": "http://glycomics.ccrc.uga.edu/ontologies"
        }
      ]
    },
    {
      "residue": "T",
      "position": 136,
      "glytoucan_ac": "G123456",
      "type": "N-Glycan",
      "evidence": [
        {
          "database": "UniProt",
          "id": "P04278",
          "url": "http://glycomics.ccrc.uga.edu/ontologies"
        }
      ]
    }
  ],

  "mutation": [
    {
      "annotation": "High frequency non-synonymous mutation in BRCA (DOID:001) cancer",
      "disease": {
        "name": "Osteoarthritis of first carpometacarpal joint",
        "icd10": "M18",
        "doid": "DOID:162",
        "url": "https://www.icd10data.com/ICD10CM/Codes/M00-M99/M15-M19/M18-/M18"
      },
      "type": "point mutation",
      "start_pos": 36,
      "end_pos": 36,
      "sequence_org": "A",
      "sequence_mut": "G",
      "evidence": [
        {
          "database": "BioMuta",
          "id": "P04278",
          "url": "http://hive.biochemistry.gwu.edu/biomuta/P04278"
        }
      ]
    },
    {
      "annotation": "High frequency non-synonymous mutation in BRCA (DOID:001) cancer",
      "disease": {
        "name": "Osteoarthritis of first carpometacarpal joint",
        "icd10": "M18",
        "doid": "DOID:162",
        "url": "https://www.icd10data.com/ICD10CM/Codes/M00-M99/M15-M19/M18-/M18"
      },
      "type": "point mutation",
      "start_pos": 136,
      "end_pos": 136,
      "sequence_org": "A",
      "sequence_mut": "G",
      "evidence": [
        {
          "database": "BioMuta",
          "id": "P04278",
          "url": "http://hive.biochemistry.gwu.edu/biomuta/P04278"
        }
      ]
    }
  ],
  "site_annotation": [
    {
      "end_pos": 40,
      "annotation": "n_glycosylation_sequon",
      "start_pos": 38
    },
    {
      "end_pos": 40,
      "annotation": "n_glycosylation_sequon",
      "start_pos": 38
    },
    {
      "end_pos": 40,
      "annotation": "n_glycosylation_sequon",
      "start_pos": 38
    }
  ]
}